wanglab/gogpt-training-data huggingface dataset:
Protein: V-type proton ATPase subunit c'' (V-ATPase subunit c'') (V-ATPase 22 kDa proteolipid subunit) (Vacuolar proton pump c'' subunit) (P23968)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:9030535}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- V-type proton ATPase subunit a, Golgi isoform
- V-type proton ATPase subunit c
- V-type proton ATPase subunit a, vacuolar isoform
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase subunit d
- V-type proton ATPase subunit B
- V-type proton ATPase subunit H
- V-type proton ATPase subunit G
- V-type proton ATPase subunit c'
- V-type proton ATPase subunit D
Sequence:
MNKESKDDDMSLGKFSFSHFLYYLVLIVVIVYGLYKLFTGHGSDINFGKFLLRTSPYMWANLGIALCVGLSVVGAAWGIFITGSSMIGAGVRAPRITTKNLISIIFCEVVAIYGLIIAIVFSSKLTVATAENMYSKSNLYTGYSLFWAGITVGASNLICGIAVGITGATAAISDAADSALFVKILVIEIFGSILGLLGLIVGLLMAGKASEFQ
Protein: Myosin binding subunit, isoform P (M9NFZ0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDGSHAR
Protein: Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (P09324)
Organism: Gallus gallus (Chicken)
Function: Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis.
Subcellular location: Cell membrane {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cell junction {ECO:0000250|UniProtKB:Q28923}.
Interaction partners:
- Catenin delta 1
- Tyrosine-protein kinase
- Growth factor receptor-bound protein 2
- Epidermal growth factor receptor
- Signal transducer and activator of transcription 3
- Receptor protein-tyrosine kinase.
- Uncharacterized protein.
Sequence:
MGCIKSKEDKGPAMKYRTDNTPEPISSHVSHYGSDSSQATQSPAIKGSAVNFNSHSMTPFGGPSGMTPFGGASSSFSAVPSPYPSTLTGGVTVFVALYDYEARTTDDLSFKKGERFQIINNTEGDWWEARSIATGKTGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYREHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGDNL
Protein: Uba3-binding protein but2 (P87167)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Uba3-binding protein but1
- NEDD8-activating enzyme E1 catalytic subunit
- S-adenosylmethionine synthase
- Ubiquitin-like protein 1
Sequence:
MQLLNSFLGFAASIAVLASSADAAPTLYKRKSKSNTNTAKSVAILDGVGVNNTFGVISYREKFPMDYHIWHTAPSTGKTYLQPWNDAVEPSTYYIDEGTFLRTGLKFAYIGDNMDLAFTNHTDWKASKHDDGTHRVDLSQRKPANNFMATQRCGKLDPFGYQLKRSKKVFQACGTQVFVGSGRSIDCQWMDSVALNLSRYYGNTEALSSLPLPRNLSADIPAKSSRLFPHGIYNFNFSAPNKRMQRFTASEATTVNGQNQSVYLTYDVPYGRSLYYYTSCALEFRFTNEFFPMDVTPNDGSAQFVVYNMSGNPKKQTTSSKGPTRLYEVARFNCTTRGCEYTQNIPCPRAGHSHTYELAPASPNTSISWIQSYSPRIGVTLQVYSNANFD
Protein: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase) (P9WQF5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
Interaction partners:
- 3-isopropylmalate dehydrogenase
- 3-isopropylmalate dehydratase small subunit
- 2-isopropylmalate synthase
- Probable transcriptional regulatory protein
- Dihydroxy-acid dehydratase
- Ketol-acid reductoisomerase
- Putative acetolactate synthase small subunit
- Glutamate synthase large chain
- Pyruvate kinase
- 2-oxoglutarate oxidoreductase subunit KorA
Sequence:
MALQTGEPRTLAEKIWDDHIVVSGGGCAPDLIYIDLHLVHEVTSPQAFDGLRLAGRRVRRPELTLATEDHNVPTVDIDQPIADPVSRTQVETLRRNCAEFGIRLHSMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGRLPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMVAPDETTYAFLRGRPHAPTGAQWDTALVYWQRLRTDVGAVFDTEVYLDAASLSPFVTWGTNPGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTAMRDIAVDAVFVGSCTNGRIEDLRVVAEVLRGRKVADGVRMLIVPGSMRVRAQAEAEGLGEIFTDAGAQWRQAGCSMCLGMNPDQLASGERCAATSNRNFEGRQGAGGRTHLVSPAVAAATAVRGTLSSPADLN
Protein: Protein PAT1 homolog (AtPAT1) (Q0WPK4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Activator of mRNA decapping. Involved in mRNA decay via decapping. Involved in disease resistance in response to biotrophic and necrotrophic pathogens. Is part of a signaling pathway including MPK4 and the disease resistance protein SUMM2.
Subcellular location: Cytoplasm, P-body {ECO:0000269|PubMed:25603932}.
Interaction partners:
- Scarecrow-like protein 21
- Scarecrow-like protein 9
- Scarecrow-like protein 4
- Scarecrow-like protein 3
- Protein PAT1 homolog 2
- Protein PAT1 homolog 1
- Protein SHORT-ROOT
- Scarecrow-like protein 13
- Protein SCARECROW
- Scarecrow-like protein 5
Sequence:
MDAFGIGSSLNQAPVTQDLKKFGDNSTGNTMFDASQYAFFGNDVVEEVELGGLEEEDEILSFTGIAEDFSFDKEEVGDSRLLSDVDDLASTFSKLNREPDVYSNTGPITDRRSSQNSLAAEWTHGEELPNWYGRQILDSDAIKDDKVWSAQPFSSLDRVEQRIPDRTKLYPEPQRQLHQDHNQQQFSSEPILVPKSSFVSYPPPGSISPDQRLGHPNIPYQSGGPQMGSPNFSPFPNLQPQLPSMHHGSPQHTGNRPQFRPALPLNNLPPAQWMNRQNMHPGDSSGIMNNAMLQQPPHQNGLMPPQMQGSQNRLPHPMQPPLGHMPGMQPQLFNSHLSRSSSSGNYDGMLGFGDLREVRPGSGHGNRQNVRFPQQGFDAGVQRRYPFRSKYMSAGEIENILRMQLVATHSNDPYVDDYYHQACLAKKSAGAKLKHHFCPNHLRDLQQRARSNNEPHAFLQVEALGRVPFSSIRRPRPLLEVDPPNSAKFGNAEHKPTDKPLDQEPMLAARVYIEDGLCLLLEVDDIDRFLEFNQLQDGGHQLKQRRQALLQSLAVSLQLGDPLAKNGQSQSLDDFLFLRVISLPKGRKLLIRYLQLIFPGSDLMRIVCMAIFRHLRSLFGVLSSDPDIIKTTNKLATVINLCIQNMELGPVSTCLAAVSCSSEQAPLRPLGSPVGDGASTVLKSILDRASELIRANNFNNAGIALWRASFNEFFNMLMRYCISKYDSIMQSLQLPPHFATEISEEAAKAIVREMPIELLRSSFPHIDEQQKRILMEFLKRSMLGSQKTEPVLS
Protein: Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-glucosaminidase) (AtNAGLU) (Protein CYCLOPS 1) (Q9FNA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the remodeling of the N-acetyl-glucosamine residues of proteoglycan complexes during reproductive development. Is essential to promote the first divisions of the zygote.
Interaction partners:
- Heparan-alpha-glucosaminide N-acetyltransferase-like protein
- Aconitase family protein
- Pentatricopeptide repeat-containing protein At2g01860
- At1g76620/F14G6_22
- Large ribosomal subunit protein bL31c
- Receptor-like protein 37
- Glutamine--fructose-6-phosphate aminotransferase 1
- Methionyl-tRNA formyltransferase, mitochondrial
- Expressed protein
- Pentatricopeptide repeat-containing protein At5g67570, chloroplastic
Sequence:
MHSIKLVLLVLLIISFHSQTVSKHHPTIDGLLDRLDSLLPTSSVQESAAKGLLQRLLPTHSQSFELRIISKDACGGTSCFVIENYDGPGRIGPEILIKGTTGVEIASGLHWYLKYKCNAHVSWDKTGGIQVASVPQPGHLPRIDSKRIFIRRPVPWNYYQNVVTSSYSYVWWGWERWEREIDWMALQGINLPLAFTGQEAIWQKVFKRFNISKEDLDDYFGGPAFLAWARMGNLHAWGGPLSKNWLDDQLLLQKQILSRMLKFGMTPVLPSFSGNVPSALRKIYPEANITRLDNWNTVDGDSRWCCTYLLNPSDPLFIEIGEAFIKQQTEEYGEITNIYNCDTFNENTPPTSEPEYISSLGAAVYKAMSKGNKNAVWLMQGWLFSSDSKFWKPPQLKALLHSVPFGKMIVLDLYAEVKPIWNKSAQFYGTPYIWCMLHNFGGNIEMYGALDSISSGPVDARVSKNSTMVGVGMCMEGIEQNPVVYELTSEMAFRDEKVDVQKWLKSYARRRYMKENHQIEAAWEILYHTVYNCTDGIADHNTDFIVKLPDWDPSSSVQDDLKQKDSYMISTGPYETKRRVLFQDKTADLPKAHLWYSTKEVIQALKLFLEAGDDLSRSLTYRYDMVDLTRQVLSKLANQVYTEAVTAFVKKDIGSLGQLSEKFLELIKDMDVLLASDDNCLLGTWLESAKKLAKNGDERKQYEWNARTQVTMWYDSNDVNQSKLHDYANKFWSGLLEDYYLPRARLYFNEMLKSLRDKKIFKVEKWRREWIMMSHKWQQSSSEVYPVKAKGDALAISRHLLSKYFP
Protein: Adenylylsulfatase HINT3 (EC 3.6.2.1) (Histidine triad nucleotide-binding protein 3) (F4K1R2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses adenylylsulfatase activity in vitro.
Subcellular location: Peroxisome {ECO:0000269|PubMed:19329564}.
Interaction partners:
- Leucine carboxyl methyltransferase 1 homolog
- Protein PALE CRESS
- Sm-like protein LSM5
- TATA-box-binding protein 2
- TATA-box-binding protein 1
- Pentatricopeptide repeat-containing protein At4g30825
Sequence:
MEARRLAILCSHLNPPGPNPTRDPTLRVSDCSSGSSGDGKVESSTLQNDCVFCKIIRGESPCLKLYEDDMCLCILDTNPLSHGHSLIIPKLHYPTLEETPPSVVAAMCSKVPLISNAIVKATGSDSFNLLVNNGAAAGQVIFHTHIHIIPRKERDCLWASESLRRHSLKLDKEASQLVSCVRRHLCSLPEEQLVQPS
Protein: Cysteine proteinase mucunain (EC 3.4.22.-) (Mucunain) (B2LSD2)
Organism: Mucuna pruriens (Velvet bean) (Dolichos pruriens)
Function: Cysteine protease. May play a role in immunity, senescence, and biotic and abiotic stresses (By similarity).
Subcellular location: Vacuole {ECO:0000250|UniProtKB:P43297}.
Interaction partners:
Sequence:
TWRSDEEVMSLYEQWLVKHGKAYNALGEKDKRFDIFKDNLRFIDDHNADNRTYKLGLNRFADLTNEEYRARYLGTRIDPNRRFVKTKTQSNRYAPRVGDNLPESVDWRNESAVLPVKDQGNCGSCWAFSTIGAVEGINKIVTGDLISLSEQELVDCDTSYNQGCNGGLMDYAYEFIINNGGIDSEEDYPYRAVDGTCDQYRKNAKVVTIDSYEDVPANDELALKKAVANQPVSVAIEGGGREFQLYVSGVFTGRCGTALDHGVVAVGYGSVKGHDYWIVRNSWGASWGEEGYVRLERNLAKSRSGKCGIAIEPSYPIKNGANPPNPGPSPPSPVKPPNVCDNSYSCSDSATCCCIFEFQKYCMVWGCCPLEAATCCDDHYSCCPHEYPICNVRAGTCLKGKNNPFGVKALRRTPAKPHWAFGGKNKVNSA
Protein: Mitogen-activated protein kinase 14B (MAP kinase 14B) (MAPK 14B) (EC 2.7.11.24) (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (cp38b) (Q9I958)
Organism: Cyprinus carpio (Common carp)
Function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Mapk14b is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MSHKERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCSALDTKSGLRVAVKKLSRPFQSMIHAKRTYRELRLLKHMKHENVIGLLDAFSPATCLAGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYINSLSYMPKRNFADVFVGANPMAVDLLEKMLVLDTDKRITASQALAHPYFAQYHDPDDEPEADPYDQSFESRDLDIEEWKRLTYEEVISFEPPVFDGDEMES
Protein: CUGBP Elav-like family member 4 (K7ERH1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
AAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY
Protein: glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Q5B1J1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase
- NADP-dependent oxidoreductase domain-containing protein
- D-xylose reductase [NAD
- Glycerol-3-phosphate acyltransferase Sct1, putative
- Uncharacterized protein
- glycerol kinase
- alcohol dehydrogenase
- alcohol dehydrogenase
- Proteasome regulatory particle subunit
- Dihydroxyacetone kinase
Sequence:
MRKNPFDMSELDAEIEANEEQQHQVRIHARQSIDGERSLLQDEERRQDDLKDRFIGAIDQGTTSTRFIIFDCVGNPVAKYQAEYRQLHEHSGWHEQDPYEMVDSVYTCIEEAMKTFLALGHSKSDIEAIGLTSQRETVLCWDWETGEPLCPSIAWPDTRTKALVRELKAQKGADELKNICGLPLSTYPSSVSLVWLLRNNEAVKQAYEEGRLAFGTVDSWLIYNLNGGLEGRHHVTDVTNASRTMLMNLETLDYDKRLLDFFGLDPKKIRLPKILPSSDPEGFGYVRSGPLEGVPITSDLGDQSAALVGHCAFTPGMAKNTYGTGCFLLYNVGEKPVISKHGLLGTVGFQLGKNRKPVYALEGSVAVAGSGVSFLMNNMGFFRDSRKVSDLAAMVPDNGGCVFVTAFSGLFAPYWIDDAKGTIFGITQHTQRGHIARATMEAACFQTKAILDAMEMDSGHSLSQLAVDGGMSNSDICMQTQADIIQIPVERPAMHETTALGAAIAAGFAIDIWKEFDELKNMNRANRTSFTPAISREQSQKMYKQWTKAVEMSRGWVDTKEMGGEDD
Protein: mRNA-decapping enzyme 1 (Q9N363)
Organism: Caenorhabditis elegans
Function: Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay (By similarity). In contrast to orthologs, does not possess decapping activity and does not remove the 7-methyl guanine cap structure from mRNA molecules. In the nervous system, negatively regulates the expression of insulin-like peptide ins-7, which in turn promotes longevity. This may in part be through promoting the activity of daf-16 in distal tissues. Required for the developmental axon guidance and regrowth of PLM touch receptor neurons. In ADL sensory neurons, plays a role in ciliary shape formation. Acts in neurons to promote larval survival at high temperatures by negatively regulating lin-14 expression (Probable).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16267265}. Cytoplasmic granule {ECO:0000269|PubMed:16267265, ECO:0000269|PubMed:31983639}. Note=Diffusely localized in the cytoplasm, but accumulates in puncta during pronuclear migration in embryos (PubMed:16267265). After pronuclear migration, accumulates in P-granules which segregated to the posterior cell, and smaller puncta scattered in the cytoplasm (PubMed:16267265). Localizes to cytoplasmic puncta in neuronal cell bodies of neurons such as touch receptor neurons (PubMed:31983639). In some cytoplasmic puncta in touch receptor neurons, co-localizes with car-1 (PubMed:31983639). {ECO:0000269|PubMed:16267265, ECO:0000269|PubMed:31983639}.
Interaction partners:
- 5'-3' exoribonuclease 1
- m7GpppN-mRNA hydrolase dcap-2
- ATP-dependent RNA helicase cgh-1
- FHA domain-containing protein
- Protein PAT1 homolog 1
- U6 snRNA-associated Sm-like protein LSm1
- Protein LSM14 homolog car-1
- Secreted protein
- NAD
- Probable U6 snRNA-associated Sm-like protein LSm4
Sequence:
MSDAKKKAAAELAAKNLAQLQKIDIAASKILDKMPFAAIYHIDAARKEWNQSNCEGTFFVYQRADRPYFSFLIANRNDPSDFIEPLTLNHILRHDGNFIYFYKDLASIQALWFHQIDDAQKIYNLLQKLVNRLKGSTTEQARAAKAASEAPQASVPAPTQAPAAPAQAPQMAPQAPPKVDLLQLIKSAQNPPQKSAATIEQMPPMLQKLMLKEPGAAMSADELEKDLIKSAKPHRNHLLQEFTNSTSAISLAAVSTKPLHGSEGDVESDIAEGEILEPLDASFVVGSGEQTPVLNKEQFISAIAHLMQTDDEFVSQIHQAYVSALNRRLNID
Protein: Sporulation delaying protein C (SdpC) (Cannibalism toxin SDP) (Killing factor SdpC) (Toxic peptide SdpC) [Cleaved into: Sporulation delaying protein (SDP)] (O34344)
Organism: Bacillus subtilis (strain 168)
Function: Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel. Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation. Addition of SDP to liquid cultures halts growth, leads to increased cell permeability and eventually cell lysis in a significant subset of the population, although some cells survive and resume growth after a lag period. Effects of SDP are irreversible within 10 minutes. Addition of SDP to solid cultures induces killing, it is much more effective than SKF (AC O31422). Has antibiotic action against Gram-positive Firmicutes (L.acidophilus, M.megaterium, P.polymyxa, S.aureus, S.epidermidis) but not Actinobacteria M.luteus or Gram-negative P.aeruginosa or K.pneumoniae. SDP induces expression of the sdpR-sdpI operon. Its maturation is dependent on SdpA and SdpB. Also functions as a ligand, binds to SdpI triggering a signal transduction cascade that protects the cell against the toxic effects of its own SDP.
Subcellular location: Secreted {ECO:0000269|PubMed:12817086, ECO:0000269|PubMed:14568161, ECO:0000269|PubMed:23687264}. Note=Produces a secreted protein originating from this gene (PubMed:12817086), secreted by the general secretory pathway (PubMed:14568161).
Interaction partners:
- Sporulation-delaying protein SdpB
- Sporulation-delaying protein SdpA
- Sporulation killing factor
- Immunity protein SdpI
- Membrane protein YknW
- Transcriptional repressor SdpR
- Putative efflux system component YknX
- Stage 0 sporulation protein A
- Putative bacteriocin-SkfA transport system permease protein SkfF
Sequence:
MKSKLLRLLIVSMVTILVFSLVGLSKESSTSAKENHTFSGEDYFRGLLFGQGEVGKLISNDLDPKLVKEANSTEGKKLVNDVVKFIKKDQPQYMDELKQSIDSKDPKKLIENMTKADQLIQKYAKKNENVKYSSNKVTPSCGLYAVCVAAGYLYVVGVNAVALQTAAAVTTAVWKYVAKYSSSASNNSDLEAAAAKTLKLIHQ
Protein: NADH-ubiquinone oxidoreductase complex I subunit (Q383T6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Complex 1 LYR protein domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Complex 1 LYR protein domain-containing protein
- FAD-binding domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Sulfotransferase
- Flavoprotein monooxygenase, putative
Sequence:
MTVARDHDIDDHDTSFTSFGGERPPFERIPVPSMASKEYTENLPAFDSDRPMPPPRSVFERFSRVMQLQFGQDPDMPLLGSRAERKYRSWLDYVTSPPSPLLPRNYVDAYTRPNPCPEEYWWASWRWPRIKYVNAKVPPPVDGKYNDYYHYLAYKNWMERERDVYVAHANLVNEMAMRCLVKEGQYNAAKNCRHLYHKGFAMSRMEELNQTLLYMALTGNAAIRETPYPENFVEEKRKIYDDWLFRTRMKKPGDVA
Protein: Fasciclin-like protein FLA12 (Q06I94)
Organism: Triticum aestivum (Wheat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MASSRRALILLAVVLAAVPAALSQKTTAPAPEAPETPDAPAAGTTPKAAAAPNVTAVLEKAGQYTKFIRLMASTQQDTQLNAQANDSDTGFTVFAPTDNAFNSLKPGTLNSLSQQDQVTLVQAHIVPTFYSMESFETASNPVRTQASGTDGPCTVNVTATSNSAVNVSTGIVHTTVGTALRATRPLAVYSVDKVLLPMDLFGPKPPASAPPAPGKKPSSAKGAAKAPSGDDEDEEDAPPAGAATAVGAGWRSLVAVVAGRHRRVPLVRRRKCERGS
Protein: Cytochrome c4 (P86052)
Organism: Thiocapsa roseopersicina
Function: Diheme, high potential cytochrome c believed to be an intermediate electron donor in an anaerobic electron transport chain.
Subcellular location: Periplasm {ECO:0000269|PubMed:17931594}.
Interaction partners:
- Cytochrome c oxidase cbb3-type subunit 1
- Cytochrome c oxidase cbb3-type subunit 2
- Ubiquinol-cytochrome c reductase cytochrome c1 subunit
- Cytochrome b
- Ubiquinol-cytochrome c reductase iron-sulfur subunit
- Ubiquinol-cytochrome c reductase iron-sulfur subunit
- Uncharacterized membrane protein YckC, RDD family
Sequence:
TDGHQAAAPQVGDPQAGEAKANGVCLACHGPQGNSLVPIWPKLAGQHPEYIVKQLMDFKQRRANEQMTPMAMPLTDQEVLDLAAYYATQPKTPGAADPELASKGESLYRWGNPETGVPACSGCHGPAGGAGQSLAKFPRLSAQHADYTKQTLEHFRGALRANDPNGMMRGAAARLSDQEIAAVSQYLQGLSQ
Protein: Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP) (Q9UBU9)
Organism: Homo sapiens (Human)
Function: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.
Subcellular location: Nucleus {ECO:0000269|PubMed:10924507, ECO:0000269|PubMed:18596238, ECO:0000269|PubMed:19864460, ECO:0000269|PubMed:23591820, ECO:0000269|PubMed:25662211}. Nucleus, nucleoplasm {ECO:0000269|PubMed:19324961, ECO:0000269|PubMed:23826332}. Nucleus speckle {ECO:0000269|PubMed:19324961, ECO:0000269|PubMed:23826332}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:23591820}. Nucleus envelope {ECO:0000269|PubMed:18596238, ECO:0000269|PubMed:23591820}. Cytoplasm {ECO:0000269|PubMed:10924507, ECO:0000269|PubMed:18596238, ECO:0000269|PubMed:19324961, ECO:0000269|PubMed:19864460}. Cytoplasm, Stress granule {ECO:0000269|PubMed:18596238}. Note=Localized predominantly in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. The association with the TREX complex seems to occur in regions surrounding nuclear speckles known as perispeckles (PubMed:23826332). Nucleus; nuclear rim (PubMed:25662211). {ECO:0000269|PubMed:23826332, ECO:0000269|PubMed:25662211}.
Interaction partners:
- Regulator of nonsense transcripts 3B
- NTF2-related export protein 1
- Regulator of nonsense transcripts 3A
- THO complex subunit 4
- Regulator of nonsense transcripts 1
- RNA-binding protein with serine-rich domain 1
- RNA-binding protein 8A
- mRNA export factor RAE1
- Serine/arginine repetitive matrix protein 1
- Nuclear pore complex protein Nup98-Nup96
Sequence:
MADEGKSYSEHDDERVNFPQRKKKGRGPFRWKYGEGNRRSGRGGSGIRSSRLEEDDGDVAMSDAQDGPRVRYNPYTTRPNRRGDTWHDRDRIHVTVRRDRAPPERGGAGTSQDGTSKNWFKITIPYGRKYDKAWLLSMIQSKCSVPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSAPPHTILNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLKLEELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPIAFDVEAPTTLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSIPFIPQNPARSSLAEYFKDSRNVKKLKDPTLRFRLLKHTRLNVVAFLNELPKTQHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRDSLRAFTRTFIAVPASNSGLCIVNDELFVRNASSEEIQRAFAMPAPTPSSSPVPTLSPEQQEMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK
Protein: protein-tyrosine-phosphatase (EC 3.1.3.48) (B6HY54)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Catenin
- Protein tyrosine phosphatase receptor type Jb, tandem duplicate 2.
- 2-hydroxyacyl-CoA lyase 2
- Hepatocyte growth factor receptor
- Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
- Hepatocyte growth factor
- Leukocyte receptor cluster member 8 homolog
- PAS domain-containing serine/threonine kinase.
Sequence:
MGQHYRLQAIVSRTTVLFVVLVSIHHGHCTDCSLCQYKTSTTTSEINVFVGNSSFCIAQNASFTNSSQTNITVTGLLPGNTYFLIISCTSVCCENFSSSPAQVQNITVVNYTNSSVTVAWTVPDGHVDSYTVNCSTQSIPNINDNNTTISSLPPGCLYNLTVTSISGVLTNVSNIVQFATKPNPPEAVRVSGQTFSSISLLWSTPLSMSGVAVSYGVSYVPVQPGVNLPLTQTTSSNMTNITNLLSGTQYTITVVTNGVNNLSSSFINLIGYTVPKIVQNLAVSNVSTNSVSLTWLPPNGTSSLFSYNINISSLGQTFYTTSNSYQITQLQPGTQYNCYVTTLIVAGNISGPSQFIQCNTKPLPVSNLKAIPVGTTVILLSWTPSTALYLYNVSANGTWSTYNSSEGANVTGLTPGNNYTFTVITVANGLSSEPVTISAFTGLGKAIIISAIGNTQTMTVQWTPPAGTVSLYSARILLMDGTVLNTKNQTKTTSMMFSDLLPGTQYSVIVSSISGPVKQDSDSVTNATLPTPPGEISTTQSTNTLNISWAQPLNMSSVSYYFLLQYNNSTLINCSQNYTSLTGLNAGFPYNIIMWTVGAMNYSSSSKSLTAFTNPSVVTNVTVNEFTETSVTLSWQQNDPQQSGYSYLLNYKTINGTSNQTTVNNNTVKLEQLQSASQYNISIIALTPGGTKSDPQFITACSRPNRVNNVSSVALNVSTVRLSWARPLQYNQLVSYQVLVSNCTKNSMNMSTSTEMITVTNLQPGTLCQISIYSVACGLLGQPVNTSVLTMPSTVQPVVNSQGSNNSLLVLWSHPDGGLDMYILNISSDGWSDFSFLNSTENNYTFTQLKAATLYTVTLTTVKGSFQETSGAVVSATYPNSPGMITVLFKNTHSVLLHWDIAQNMTPGSFNYSLSFWSSKNNSLYLTPNNTLLLDGLQSGTPYNVSLATVGPLNLQSESMRYNVTTMPDPVKNLKVVSTTTNTISVTWKMVDVPKYVVSVNNAVKITSSNNMTIHNLQPSTQYNISVQSSTFDNTEGEAVCLQDCTDAAPVENVTCVGPNLTLPMLNLFWNHPLGGYMNFEVNLSSSISEKTKNLNYNFTGLKYNKTYSVTLRTLGCGKSSTVKNISCTTGFTNPVVPKITAASVSEQQYNKFALVIQSDAFNDSNGTVCSYGLLVSSGSFDCLDNNQNYNQCLLKTYDDWKAKQSDTFLAVVKTNVSKSELETIIIGDGSKWNKYTNGELNAKGTYNFAIVAFTLLEVKDGKVDVSKSYYSVSAYQSVTLPENPVVIGGAAAGVGVTVIIVVIIIGIVACTRKKRKEVSNSVPIHSLRNKVSDPIKVEDYEAYYKRQRADSFCGFAEEFEDLRPVGINQSKTVAVFPENKAKNRYNNVLPYDSSRVKLSVLSSPFDDYINANYMPGYITKKEFIAAQGPLPGTVNDFWRLIWEKNVHTIVMLTKCNEQGRVKCEEYWPAEMKTFSNLTVTTISDIPLEDWTLRDFEVKNMKTAEIRSVRHFHFTAWPDHGVPETTELLINFRHLVREHMDEYSRHSPTLVHCSAGVGRTGTFIAIDRLIFQIERDGVVDVYGIIHDLRMHRPLMVQTEDQYVFLNQCAMDIIKSRTGNNVDLIYQNTAALTIYENFEPLKKGKNGYHKA