wanglab/gogpt-training-data huggingface dataset:
Protein: IST1 homolog (Charged multivesicular body protein 8) (H3BRE2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIW
Protein: NADPH-dependent FMN reductase ArsH (EC 1.-.-.-) (Arsenical resistance operon protein ArsH) (B7J950)
Organism: Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))
Function: Has NADPH-dependent FMN reductase activity and high NADPH-dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH-dependent ferric reductase in vivo.
Interaction partners:
- Arsenical pump membrane protein
- Arsenate reductase
- Transcriptional regulator, ArsR
Sequence:
MSGNLPNTDDVLLQVPDVRCLRSAAETDHPPRILLLYGSNRECSYSRLLTLEAERLLRYFGAETRVFHPTGLPLPDDAPVTHPKVVELQELVEWSEGQVWCSPERHGAMTGVFKSQVDWIPLNSGAIRPTQGKTLALMQVCGGSQSFNAVNQMRILGRWLRMLTIPNQSSVPKAFLEFDDGGRMKPSAYYDRVVDVMEELMKFTLLTRGNSDYLVDRYSERKESAEELSRRVNLQNL
Protein: Small ribosomal subunit protein uS2 (40S ribosomal protein S0) (O42817)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
Subcellular location: Cytoplasm.
Interaction partners:
- Small ribosomal subunit protein eS24
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein uL6
- Small ribosomal subunit protein eS30
- Large ribosomal subunit protein eL18
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS8A
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein uL3
Sequence:
MSLPASFDLTPEDAKLLLAANVHLGAKNVQVHNKPYVYKTRPDGMNIINIGKTWEKIVLAARIIAAVPNASDVAVCSSRTFGQRAVLKFAAHTGATAIAGRFTPGNFTNYITRSFKEPRLVVVTDPRTDAQAIKESSYVNIPVIALTDMDSPSEYVDVAIPCNNKGKHSIGLIWWLLAREVLRLRGIIPDRTTEWSVMPDLYFYRDPEEIEQNAVEEAKTEEVEEAPVAEAETEWTGETEDVDWADSGATPAAEDAAASNW
Protein: Transmembrane protein 65 (Q6PI78)
Organism: Homo sapiens (Human)
Function: May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contribute to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (By similarity). May also play a role in the regulation of mitochondrial respiration and mitochondrial DNA copy number maintenance.
Subcellular location: Cell membrane {ECO:0000269|PubMed:26403541}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion inner membrane {ECO:0000269|PubMed:24765583, ECO:0000269|PubMed:28295037}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes at the intercalated disk in the ventricular tissue (PubMed:26403541). {ECO:0000269|PubMed:26403541}.
Interaction partners:
Sequence:
MSRLLPLLRSRTARSLRPGPAAAAAPRPPSWCCCGRGLLALAPPGGLPGGPRRLGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLKELHRFESIAIAQEKLEAPPPTPGQLRYVFIHNAIPFIGFGFLDNAIMIVAGTHIEMSIGIILGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQVDMWQTRLSTHLGKAVGVTIGCILGMFPLIFFGGGEEDEKLETKS
Protein: RNA binding motif protein 10 isoform 2 (A0A0S2Z4W4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ
Protein: Rho GTPase activating protein at 19D, isoform C (Rho GTPase activating protein at 19D, isoform E) (M9NFH4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLQNSNGAAAAHSAASAVATPAAAASAAAAAAAAAVAAAANNAALAASSIQPKLIVIRRRPNQGFGFTLRHFIAYPPEDDQASSSASGLVSGSATAATAASVSTNWPQEASSAAGSNSGSSSSVGVAGITGLEPTSPTSLPPYQVKAMETIFIKEVQANGPAHYANLQTGDRVLMVNNQPIAGIAYSTIVSMIKQTPAVLTLHVVPKECDVLQMHYTSIAHTPESNRLTMSTHSPSLLANGSHKTTFPAAAAVAAPPHQHQQQQQQLISYPAVAAVTTSTPAGSPQSQSQSQSHSHPNTHHAPSLHGGSRSGSITSTASGGITVLSQPFYPQQQQQQQQQQQHRHPALTGGSSSIDFGDMAHGLRQHQQQQQHLYQQQQQHHQFMRANQPPNLTVLSASSATNTPTPTARQPKSATSHNQALYAVGAGPSSAAGSGSGSLSGGSENSDLMIRLRESIKQKEEFLKSPVPASMSSASSINGNQAQSSSPAQQQHLQQHQQHFFPSHTPPGGVQVVVPPPRSRHQVMLKQQQQQQQQHQQHHVLGYDMYHSGGKLVQRSSTAPGSVCHQHQQQQQHHLYHQQQHQQLQQTQHRQVMINNNAKYAKDLDYFETLQETGVTNKVFERKLVSHMSKGFDPFKPLSINTSALESSASTSSTSATTTVKKQSVLYESLQQHPLAKYHQTQQQTTTTTTVDGQTSSRMELHKATLANATIDPVPVGSSKFVTLPDKPDKGSSVATLADIAESSAAAIVDSASGSGNVVRRYKPLSSSSFDEGKPMRRISYLRATNNETDFNAEAAAGGDAAATGASGPASASAASSAPGPTPSSAPAPAPAPAPLPISIPIPVAAVVEPQKTKSLVEEHPDPTYDVIGGTGGGHEFIETPNGLEDVRLSAHGSRRASMSSDMRSSIHIDAELNGKYVPNELEAFETEIEIKSSCINGKRMSEYRSWRQVKLEIKGDLLRIYSGRHAKSEHNVIELDIRNFKFFDESMDKKKYLIRMQSKPSPSGAHLASLGNELNLDEGHDKLLTSSGSSSANEPAANAASALTASTSSSTCSSGPYTEILFKTKSSNEMKRLFGLLQWKDSLNYDDNEHQPQGKQLAEPQKTVASASYLDDVQGGASAADSSPLSSHSGGIADASGSHHVSALPAAAAIVAATSDSISPVMKARKSSSHKHIPDKDLGSPKSKNWKDLLFRRGGSGSGGVSHHDLASPSACAAKQIGSIGVPLRSCPMSKVNAYVPHLVEVCTNIVETKGLGVVGIYRIPGNKAAISELSELVNTKDFQFESCASDDRWEDVNVVSSLLKLFIRSLPDALMPASYYINFIEADKKFGLERIVLLREIVESLPRHPYETMKHLIRHLCRVSGNCDVNRMEPKNLAIIFGPSIIRTPNDTLETAVKDMKHQCRIVELLVTQYDYFFEGGSLPDIAEVSGGTAAVSAAQPQQQTQEDQTSMLLHNLSKIERITERETTRTSRFMPQLRRKTHGKRSAVNSDTYSGESVLSLDYAKASASASASASSTASTSSSSTLHSGGKASASSSSSSTTKFSSSSSSACSTTAVAISSSISATSSKLLSANFKKRSTGGFLGSRSSHQTRKASLDEKDSGQSSGSLGHSLGVGINLAKEQQRSSVDISILLTDDDSSSRLSDTGSMSLTTITDTLDSKLRNLRSGSESNDENGSPEFPKNRRHTLGQPLHMHSENIPYADESPERLFHQFCNPLETAPLSLHLSRSCTATNTIGGDEKPSKQSGGVAPLPPSLLKAAHKLQHSATVPIHQGSSTAPTSGAATPVGTPTGSGGAGAIPSRSSSSSVTTLTKSIQPRFSNYLSYERGNAAAGGAERVVGSAGGAASDDDSEGSTTSDPKEKLLLGERPSPSFFIERYNKKRRDHRLFRSASFNCRNYSTRHITAQTSGGVAAGVSGGVAGAVAVGVACCQALSTTGLTKDEKTDMNLTKKRQIQNKQNRSIKRRHTVGGPHDYSASNGGCSNHSHGHDLAAINYNHHNRHHQQQLLKLGSATSGGGGSGAAAAETTTTTTTTTTVLRRLGTGQAGAEASVALPASSSGSSSNNNNSPQSDGSNGNGGGVAGVASNAPPTGVGVGGNNSSGSSSNSSSTSTTPAGNGDQVLEVGIRIKNISRGRF
Protein: Ras and Rab interactor 3 (Ras interaction/interference protein 3) (P59729)
Organism: Mus musculus (Mouse)
Function: Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8TB24}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q8TB24}. Early endosome {ECO:0000250|UniProtKB:Q8TB24}. Note=Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles. {ECO:0000250|UniProtKB:Q8TB24}.
Interaction partners:
- Myc box-dependent-interacting protein 1
- CD2-associated protein
- Ras-related protein Rab-31
- Cas scaffolding protein family member 4
- Sodium/potassium/calcium exchanger 4
- Thioredoxin domain-containing protein 3
- Ras-related protein Rab-5B
- Alsin
Sequence:
MRRAEAPSSAHPAGPIPDAGKGEGEEDEEKDGTRLGLSTTPRNCIPRRGISVLEKLVKTCPVWLQLGLGQAEAAKILQQEMAGMFLVCRDNNLKQLVLCVHFPSLKGSSAEVLEYPIKEEKAILYLEGSVLVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFLELETISNLGLGFWDSSLNSRGSAEPLRSPAPGTPASSSLRPTTHYANCSCEIELSVGNDRLWFVNPIFIEDCILPADPPPLPTGSYPPRPTPATPDATSPTSKGSPRRPPPPPPLPTVPPTGPARPLAPPVPPAGPLPNSPLTPTSHLAPHAPGPPGHSNQPPMTACESLPRPAVGLGPFGEEEMKPGTTPNPLHQAPPPPLPLKKALPAAPPRRRISERVSLESQNVGTSTDRDHSGISRTASLNLPPQSTVSSLGDRPPRTTEQSQDTEAKASHADSIPVPPGKAKQPPVPPPRKKRVSRQLASTLLSPLESPIQEASSEKQATGASWEGLSPVRQAGMQHLQVQSSSCPQSSPEFKGSQASLSDSLGVPASAADQDSYSTSSAEEELEFSSPNVKKKPSMILDKARHRLSFVSFASVFHAFLSSDRKLYKKVVELAQDKSSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVEPTLHSEEELEAIVESALYKCVLKPLKEAINSSLLEIHSRDGSLQQLKENQLVVLATTTTDLGVTTSVPEVAVMEKILQKLTSMHKAYSPGKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKNYDKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLKPEQQSRTLASRADTAAQALCAQCAEKFEVSQPQDYRLFVLVDGRCFQLADEALPHRIKGYLLRSEPKRDFHFVYRPQDSGKDASSQPCIVVREPNFL
Protein: Flagellar hook protein FlgE (P0A1J1)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Subcellular location: Bacterial flagellum basal body {ECO:0000250}.
Interaction partners:
- Flagellar P-ring protein
- Flagellar biosynthetic protein FliQ
- Flagellar basal-body rod protein FlgG
- Flagellar basal body rod protein FlgB
- Peptidoglycan hydrolase FlgJ
- Flagellar motor switch protein FliG
- Flagellar motor switch protein FliM
- Flagellar basal-body rod protein FlgC
- Flagellar hook-associated protein 1
- Basal-body rod modification protein FlgD
Sequence:
MSFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFAGSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKLDENRNLVNMQGMQLTGYPATGTPPTIQQGANPAPITIPNTLMAAKSTTTASMQINLNSTDPVPSKTPFSVSDADSYNKKGTVTVYDSQGNAHDMNVYFVKTKDNEWAVYTHDSSDPAATAPTTASTTLKFNENGILESGGTVNITTGTINGATAATFSLSFLNSMQQNTGANNIVATNQNGYKPGDLVSYQINNDGTVVGNYSNEQEQVLGQIVLANFANNEGLASQGDNVWAATQASGVALLGTAGSGNFGKLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) (A1Z9S1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis and membrane trafficking in synapses. In response to high synaptic activity at neuromuscular junctions, stabilizes Pldn protein levels and, together with Pldn, plays a role in promoting efficient synaptic vesicle recycling and re-formation through early endosomes.
Interaction partners:
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- SNAPIN protein homolog
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- Dysbindin protein homolog
- Biogenesis of lysosome-related organelles complex 1 subunit 4
- Biogenesis of lysosome-related organelles complex 1 subunit 3
- Biogenesis of lysosome-related organelles complex 1 subunit 5
- Uncharacterized protein, isoform A
- KxDL motif-containing protein CG10681
- BLOC-2 complex member HPS5 homolog
Sequence:
MLTSMVKEHHKEQAKRKQEQEVRRKEAIEASNELTQSLVDTLNVGVAQAYLNQKRLDAEAKQLHLGATNFAKQTHQWLQLIDQFSTALKDLGDVENWARSIEGDMHTINQTLELAYKASRATQTSSGAGTSLEASTSASASANPSAT
Protein: G2/mitotic-specific cyclin-B2 (P30276)
Organism: Mus musculus (Mouse)
Function: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Interaction partners:
- Cyclin-dependent kinase 1
- Cell division cycle protein 20 homolog
- Serine/threonine-protein kinase PLK1
- M-phase inducer phosphatase 3
- Cell division cycle protein 27 homolog
- Cyclin-A2
- Baculoviral IAP repeat-containing protein 5
- Kinesin-like protein KIF20A
- G2/mitotic-specific cyclin-B1
- Borealin
Sequence:
MALLRRPTVSSDLKNIDTEVIPKAKSHVTIRRAVLEEIGNKVRNRTTQVAKKPQNTKVPALPTKVTNVNKQPKPTASVKPVQMEALAPKDRPPAPEDVSMKEESLCQAFSDALLCKIEDIDNEDRENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLGQGKWNLKQQYYTGYMESEVLEVMQHMAKNVVKVNDNRTKFIAVKNKYASSRLLKISTIPQLNSKIIKDLASPLLGSP
Protein: Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (hFAN1) (Myotubularin-related protein 15) (Q9Y2M0)
Organism: Homo sapiens (Human)
Function: Nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Not involved in DNA double-strand breaks resection. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Probably keeps excising with 3'-flap annealing until it reaches and unhooks the ICL. Acts at sites that have a 5'-terminal phosphate anchor at a nick or a 1- or 2-nucleotide flap and is augmented by a 3' flap. Also has endonuclease activity toward 5'-flaps.
Subcellular location: Nucleus {ECO:0000269|PubMed:20603015, ECO:0000269|PubMed:20603016, ECO:0000269|PubMed:20603073, ECO:0000269|PubMed:20671156, ECO:0000269|PubMed:20935496}. Note=Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2 (PubMed:20603015, PubMed:20603016). Localizes to stalled replication forks via its UBZ4-type zinc finger (PubMed:20935496). {ECO:0000269|PubMed:20603015, ECO:0000269|PubMed:20603016, ECO:0000269|PubMed:20935496}.
Interaction partners:
- Fanconi anemia group D2 protein
- DNA mismatch repair protein Mlh1
- Fanconi anemia group I protein
- Mismatch repair endonuclease PMS2
- PMS1 protein homolog 1
- Myotubularin-related protein 10
- Structure-specific endonuclease subunit SLX4
- Transient receptor potential cation channel subfamily M member 1
- Structure-specific endonuclease subunit SLX1
- DNA cross-link repair 1A protein
Sequence:
MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHLDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKREVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSSPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACHCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQGSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPDLVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS
Protein: Haloacid dehalogenase-like hydrolase domain-containing protein At4g39970 (EC 3.1.3.-) (Q680K2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Haloacid dehalogenase-like hydrolase domain-containing protein At2g33255
- Catalytic/ hydrolase
- 
- Scarecrow-like protein 14
- Sugar transport protein 13
Sequence:
MAVSCNHSAILFSPSSTAGSSSVTSSSSLIGFPRFQTLRFKSRSVYSKSRVSSPVSALPLRSLEALIFDCDGVILESENLHRQAYNDAFSHFDVRCPPSSSESLDWSLEFYDKFQNLVGGGKPKMRWYFKENGWPTSTIFDSPPQNDDDRAKLIDTLQDWKTERYKEIIKSGSVEPRPGVIRLMDEAKAAGKKLAVCSAATKSSVILCLENLIDIERFQGLDCFLAGDDVKEKKPDPSIYITAAEKLGVSVKDCLVVEDSVIGLQAATKAGMSCVITYTSSTSDQNFNDAIAVYPDLSNVKLKDLETLLQTIVTAA
Protein: Protein C2-DOMAIN ABA-RELATED 1 (Q9FHP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Stimulates the GTPase/ATPase activities of Obg-like ATPases (By similarity). Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity. Binds liposomes in the absence of exogenous Ca(2+), but this activity is enhanced in the presence of Ca(2+) and generates membrane curvature (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:25465408}. Nucleus {ECO:0000269|PubMed:25465408}.
Interaction partners:
- Putative disease resistance protein At1g50180
- AT5G18310 protein
- Zinc finger protein WIP6
- G-protein coupled receptor 1
Sequence:
MENLVGLLRIHVKRGVNLAIRDISSSDPYIVVHCGKQKLKTRVVKHSVNPEWNDDLTLSVTDPNLPIKLTVYDYDLLSADDKMGEAEFHIGPFIEAIKFAHQLGPGLPNGTIIKKIEPSRKNCLSESSHIVLNQGKIVQNMFLRLQHVECGEVELQLEWIDVPGSRGI
Protein: FI07430p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Q9VWG2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Paired amphipathic helix protein Sin3a
- Histone deacetylase HDAC1
- Histone deacetylase complex subunit SAP30 homolog
- Histone deacetylase complex subunit SAP18
- Chromatin assembly factor 1 p55 subunit
- BRMS1 transcriptional repressor
- Inhibitor of growth protein
- PHD finger protein 12
- BRCA2-interacting transcriptional repressor EMSY
- Sin3A-associated protein 130, isoform C
Sequence:
MSNYYSLLLQADTYDDESIGDERSEEDTDDASETEFRSPSRYGAMNGTSNSNNMGTNSELKEQMYQHKLFNLQKQMEELGQLVHPEYLKRVKKLDSQLKERRRMNEVYKEYMRECVERDYVLEKMAAQKEYDEKMMDLKDNLISDFEDRKRQIENERFSIELTNDSMEIKTTITRKLRRRPNEPLPVIEKRRKPATGQLLVYQLDDKEIESDLKIIQRGRPNPVPQQNGSGSYGSGSQQQQSMHVLAEPTSNSGLVETRIEDNKLLYERRWFCRGQQVYVEGKEMSKFAATITAIGNEVVWVKRTNETKVKINMSHLAKGKISIKRR
Protein: Glucose-6-phosphate isomerase 1, chloroplastic (GPI 1) (EC 5.3.1.9) (Phosphoglucose isomerase 1) (PGI 1) (Phosphohexose isomerase) (PHI) (Q8H103)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes the synthesis of starch in leaves.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:18431481}.
Interaction partners:
- Probable phosphoglucomutase, cytoplasmic 1
- Probable phosphoglucomutase, cytoplasmic 2
- Phosphoglucomutase, chloroplastic
- Triosephosphate isomerase, chloroplastic
- Triosephosphate isomerase, cytosolic
- Hexokinase-3
- Hexokinase-like 1 protein
- Hexokinase-1
- Probable hexokinase-like 2 protein
- Hexokinase-4
Sequence:
MASLSGLYSSSPSLKPAKNHSFKALPAQSRDSFSFPHTSKPTNLPLTLSSARSVARDISHADSKKELLKDPDALWKRYLDWFYQQKELGLYLDISRVGFTDEFVAEMEPRFQAAFKAMEDLEKGSIANPDEGRMVGHYWLRNSKLAPKPTLKTLIENTLDSICAFSDDIISGKIKPPSSPEGRFTQILSVGIGGSALGPQFVAEALAPDNPPLKIRFIDNTDPAGIDHQIAQLGPELASTLVVVISKSGGTPETRNGLLEVQKAFREAGLNFAKQGVAITQENSLLDNTARIEGWLARFPMYDWVGGRTSIMSAVGLLPAALQGINVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQLVMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLRDRPPGHDWELEPGVTCGDYLFGMLQGTRSALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLALQKRVLSVLNEATCKDPVEPLTLEEIADRCHAPEEIEMIYKIIAHMSANDRVLIAEGNCGSPRSIKVYLGECNVDDLYA
Protein: Protein lin-2 (Abnormal cell lineage protein 2) (P54936)
Organism: Caenorhabditis elegans
Function: May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions.
Interaction partners:
- Protein lin-7 homolog
- Protein lin-10
- PDZ domain-containing protein
- Liprin-alpha
- SH3 domain-containing protein
- MAGUK p55 subfamily member 5
- Neurexin-3-beta
- Disks large homolog 1
- NMDA-type ionotropic glutamate receptor NMR-2
- Protein Scribble homolog let-413
Sequence:
MRELDPDESNLLLDEQLSIRDVIEQGPFSNVYRILHGPSNRKFLLRSINLNLFRQHTGLGFEEIDEEIRICQNLQHPYICRLEKTINSVHYRHIIFENMEGNDICFEIVQRASNGFVFSEYVVSHYTRQLLDALDYCHTRKIVHRDVRPHNLVLASKDTSAPLKLCGFGVAKDLSEIGGSMACGRVGVPQFMAPEIVRKDRVSCSSDIWSSGVVLFLLLAGRLPFSGSTSDIYERIMQTDVDVDGYMPNISESARNLVRRMLNADPSKRISAKEALNHEWIRDKEHMASRKHMNDVIDQMRRYNESRKLKSNVLSAVNSGRFDETTPRQDTPQTAFVDGSSPGGDCCHRGESSSNDAAEPPADKDLSGAYKVLGSLDAINSLLDPNSYKPGSTTFQKIHDDGSVRNLLRLYDKIKALPCEPVVTEVDTSTLRKETLNQIDGLLGPSPEALELRQLLNSPHLASCVQALDVVVCEIRDPKNEASGSGDKEGNCVSSDPAPAYLNGGVLPLGAQRAGTSFEHFNQSAVHTSYDEEEEELYDCMSRLRLVQFQKDTQEPMGITLKVNEDGRCFVARIMHGGMIHRQATLHVGDEIREINGMSVANRSVESLQEMLRDARGQVTFKIIPSYRSAPPACEIFVRAQFDYEPSQDDLIPCPQAGIPFKTGDILQVISKDDHNWWQARFVSSFPSIGNSSNAQRSNQQQVAGLIPSPELQEWRTACLAMERSKNTCNTHCMWFNKKKKYYTTKYLQKHSALFDQLDLVTYEEVMRLSQYRRKTLVLLGAHGVGRRHIKNTLIHRHPNRFAYPIPHTTRPPRKDEVDGKHYYFVTNEQMMADIQNNEYLEYGTHEESMYGTKLETIRNIHKSGKIAILDVEPQALKVLRTAEYSPFVVFIAAPNLQGMQDPDGSLEKLLNESDVLRQAFGHLFDFIITNSDIDDTIAQLERLVEKLPAYPQWLPVTWVY
Protein: Substrate-adhesion molecule (Q8I7T3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in substrate adhesion, myosin-independent cytokinesis, organization of actin cytoskeleton, and phagocytosis.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative phagocytic receptor 1a
- Integrin beta-like protein A
Sequence:
MKSQKIGSMILLIGILLAIFNFAYSDDDIERFSINPEKPISFTSDQPGFPTSADFPIGSILANSFYSFGGDVNYFQLNISLMEEFSKDGNTGSQATWNQYTSVPVSPISSAVTANRVYTMSIGSLNRVKKGDITSMESTDFLNDEKYSSLVTTLNGGVSYGDDVFFLSSKSATGEAVLIHINDTATGTFGTSSYDEILLDAAINDPSSITVDSKLGLAFIGDSDGDILVFNMTLKAKIAIYSNSSIANLRSSGVVDEERQLLYICGQAGGMNSYITQVDIFHYSATDITLLHSFTILGSLCPSAGIDVKGGQLFFSTTTSSGSQLIGTDTSGGNTGSLSENIANTQSVAISVDSITKTISVFYPDSVFYGTFKSICPSDCSGHGECNYGTCVCDHNYQGQGCEEELCLTLNNCTGTDNGKCENGFCYCSSEWEGAQCEIRRCKDSCNGYGTCNTANYTCVCDSAHMGETCNELVPPPPCTYYTDSESCLSRTTCGWCEVDGLCKEGDRYGPFEGFCRTWFFDTNVETGVIALACIFIAFVGILYIIDIGTTVPIDIKRAKDYAEENKSGQFPKATHEEASVLWWRDQRSHKAWTFMDQFQLISLVSHIGVVFPSRFISFTEYLDWSNLGIPLPPSINPPQIWSVPTDWTSNTARTILSMAQYENSLGSGDLYLLPNILFWFGLLLGVFLVPLLLAYAIISFMESLIHWKEVVTNRLIHVLVRILTFGYIGVLIAASFAMVTPLHDYRIIIPGAIIFVLYGIGLPIAIWFLLAVPEARLHNPTFKQRFGCLYVHYKPKTDHRFVVFMFIKRFIMAVIIGILSFKPMTNYPLTGTDLAVPIVQVVVIDIALIGYAVLLFIRKPYFDHYQLWLEYLLTAINIVTVSLSLTHIKSPSAAGELIACLIQALALVACIAAYVVAWLQMRSSFIKKVKKYLCCCCKSSKSSGEIDLSKK
Protein: Nucleoside hydrolase 3 (Adenosine nucleosidase) (EC 3.2.2.7) (Inosine nucleosidase) (EC 3.2.2.2) (Purine nucleosidase) (EC 3.2.2.1) (Q8RY23)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Extracellular purine-specific hydrolase present in the apoplastic fluid involved in the degradation of extracellular nucleosides, including inosine and adenosine, and which may participate in wound and pathogen responses (e.g. Botrytis cinerea).
Subcellular location: Secreted, extracellular space, apoplast {ECO:0000269|PubMed:21235647}. Note=Present in the apoplastic fluid. {ECO:0000269|PubMed:21235647}.
Interaction partners:
- Equilibrative nucleotide transporter 3
- Equilibrative nucleotide transporter 1
- Equilibrative nucleotide transporter 6
- Nucleobase-ascorbate transporter 3
- Nucleobase-ascorbate transporter 12
- L-type lectin-domain containing receptor kinase I.9
- Adenine phosphoribosyltransferase 1, chloroplastic
- Thylakoid lumenal 15.0 kDa protein 2
- Phenazine biosynthesis PhzC/PhzF protein
- Bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial
Sequence:
MLTSPTLKSLWFLFTILGLLGQNLPCVLSSSHRILVDTDVDTDDLFAILYLLKLNKSEFDLVGITLSANAWTNAGHAVNQVYDLLHMMDRDDIPVGVGGEGGISDDGTIHSDVGGYFPIIEQGMTTTGECRYRQAIPKGLGGLLDIDSNYGFRKQFLPQGNRRYTPLQQPTAQKVIVDKISEGPTTVILLGSHTNFALFLMSNPHLKHNIQHIYIMGGGVRSQNPTGCCPANSTVAECQPRQCGNRGNLFTDYTSNPYSEFNIFADPFAAYQVFHSGVPVTLVPLDATNTIPINQKFFETFENNYQRTYEAQYVFLSLKIARDTWFDDEFYKSYFMWDSFTAGVAVSIMRNSANKNNKNGENDFAEMEYMNITVVTSNKPYGRSDGSNPFFDNRRTPKFNLALGGVHSGHVQTGLRDPTCLPKSGIGRGKCKDGYTQEISGSDSVRVLVATRAKPNINIKSKLDREFYVDFLEVLNRPEETGRFNFSSQFPYYKEELFRPDLSKTRPGKPVVFDMDMSAGDFLSLFYLLKVPVDKIDLKAIIVSPTGWANAATIDVVYDLLHMMGRDDIPVGLGDMLALNQSDPIFPPVGGCKYVKAIPRGCGGFLDSDTLYGLARDLPRSPRRYTAENSVTHGAPRDTDRPELRQPLAIEVWQNLTKSGNGVSKITVLTNGPLTNLAKIISSDKKSSSLIKEVYIVGGHINREKSDKGNIFTIPSNAYAEFNMFLDPLAAKTVLESALNITLVPLATQHKLSSFQTMLDRLYSSTKTPEARFVKRLLVRLQALHQKHRRYTHIDMFLGEVLGAVLLGGDDASLKPKMRAEHIKVIAEGDESRDGKILIDKLRGKQIKILERVDLISISESFASRLDDKKQSAVIGSFEEQKKIWSTPPS
Protein: Lens fiber major intrinsic protein (A0A0K0LT60)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cell junction {ECO:0000256|ARBA:ARBA00004282}. Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Filensin
- Filensin
Sequence:
MWEFRSMAFWRAVFAEFFGTMFFVFFGIGAALRWTTGPHHILHVALCFGLAAATIIQSIGHISGGHINPAVTFAYLVGSQMSLFRAFFYWAAQFLGAMAGAAVLYGVTPKNMRGNMALNMLQPGISLGMGTTVEVFLTMQLVICIFAVTDERRNGRMGSAALSIGFAVTVGHLMGMYYTGAGMNPARSFAPAVLFRNFVNHWVYWVGPMIGGAMGALLYDFMLFPRMRGLSERLATLKGSRPPETETQQDTRGEPIELKTQAL