wanglab/gogpt-training-data huggingface dataset:
Protein: Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit) (P26369)
Organism: Mus musculus (Mouse)
Function: Plays a role in pre-mRNA splicing and 3'-end processing. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Positively regulates pre-mRNA 3'-end processing by recruiting the CFIm complex to cleavage and polyadenylation signals.
Subcellular location: Nucleus.
Interaction partners:
- Splicing factor 3B subunit 1
- Splicing factor U2AF 35 kDa subunit
- Splicing factor 1
- Splicing factor U2AF 26 kDa subunit
- Splicing factor 3B subunit 4
- Serine/arginine-rich splicing factor 1
- Splicing factor 3B subunit 2
- U2 small nuclear ribonucleoprotein A'
- Splicing factor 3B subunit 3
- Serine/arginine-rich splicing factor 2
Sequence:
MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
Protein: Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5) (Q9R016)
Organism: Mus musculus (Mouse)
Function: Sensor component of the NLRC4 inflammasome that specifically recognizes and binds flagellin from pathogenic bacteria such as Legionella or Salmonella. Association of pathogenic bacteria proteins drives in turn drive assembly and activation of the NLRC4 inflammasome, promoting caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria. The NLRC4 inflammasome senses Gram-negative bacteria such as L.pneumophila and P.aeruginosa, enteric pathogens S.typhimurium (Salmonella) and S.flexneri. May contribute to prevent motor-neuron apoptosis induced by a variety of signals (By similarity).
Interaction partners:
- NLR family CARD domain-containing protein 4
- NACHT, LRR and PYD domains-containing protein 1a
- Caspase-1
- Baculoviral IAP repeat-containing protein 1f
- Baculoviral IAP repeat-containing protein 1b
- NACHT, LRR and PYD domains-containing protein 6
- NACHT, LRR and PYD domains-containing protein 3
- Interferon-inducible protein AIM2
- Apoptosis-associated speck-like protein containing a CARD
- Caspase-4
Sequence:
MAEHGESSEDRISEIDYEFLPELSALLGVDAFQVAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVRLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKRPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQSYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRESNHGDAAAVHSTVVDLGRSEAQWFQEARSLSEQLRDNYTKATFRHMNLPEVCSSLGTDHLLSCDVSIISKHISQPVQEALTIPEVFSNLNSVMCVEGETGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICAQLLGAGGCISEVCLSSSIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNRVRDIRLYLGTSLEIQEFPFYNTVSVLRKFFSHDIICVEKLIIYFIDNKDLQGVYKTPLFVAAVCTDWIQNASAQDKFQDVTLFQSYMQYLSLKYKATAEPLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDEKLTTLLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQIDSPLKAINSFNIFLYYVSSHSSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPQTFLWFQFVRGLWLVSPESSSSFVSEHLLRLALIFAYESNTVAECSPFILQFLRGKTLALRVLNLQYFRDHPESLLLLRSLKVSINGNKMSSYVDYSFKTYFENLQPPAIDEEYTSAFEHISEWRRNFAQDEEIIKNYENIRPRALPDISEGYWKLSPKPCKIPKLEVQVNNTDAADQALLQVLMEVFSASQSIEFRLFNSSGFLESICPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPEQLFHNLHKFLGLKELCVRLDGKPNVLSVLPREFPNLLHMEKLSIQTSTESDLSKLVKFIQNFPNLHVFHLKCDFLSNCESLMAVLASCKKLREIEFSGRCFEAMTFVNILPNFVSLKILNLKDQQFPDKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLTFHDILDDDSVIEIARAATSGGFQKLENLDISMNHKITEEGYRNFFQALDNLPNLQELNICRNIPGRIQVQATTVKALGQCVSRLPSLIRLHMLSWLLDEEDMKVINDVKERHPQSKRLIIFWKLIVPFSPVILE
Protein: GD11266 (Lethal hybrid rescue) (A0PKA7)
Organism: Drosophila simulans (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00371}.
Interaction partners:
- Hmr
- GD19500
- GD22699
Sequence:
MSTDSAEETAIHSTVPHLEINISNTNNSGQIVLNDVLLMEMLARYPFLIIPQVEPKMDVEYNAWGWDQLTKSFNQSYESVELSTPFSVTELKLRWVKLRPLLKAFAASKGQITEPLWREMNDVHKLQIPEPLRRVMNDVHIRMQSAKPADVPKTKCQEFLLSQLPFVKSLSPAERRHLEVEVLDIILEQERQEKATRQLGPMELKTVQSEYEEFLKAIRVKELPANTLLSPAIDGFRISPRNIRPNLASANKRISYNGVSNESNYVKIKTETAIEPKIEDATKFDERPIETPRYVPLKSAKYYIKSCRIRVKRVEIDDYLPLARILRSRRPTLRT
Protein: Protein phosphatase inhibitor 2 (IPP-2) (P50411)
Organism: Rattus norvegicus (Rat)
Function: Inhibitor of protein-phosphatase 1.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Sequence:
MAASTASHRPIKGILKNKTSTTSSVVASAEQPRRTVEEELSKKSQKWDEMNILATYHPADKDYGLMKIDEPDTPYHNMIGDDEDVCSDSEGNEVMTPEILAKKLAAAEGSEPKFRTREQESSGEEDNDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMSETADADSMNIEESNQGSTAGDHLQHKSQSS
Protein: Putative acyl-CoA thioester hydrolase YbhC (EC 3.1.2.-) (P46130)
Organism: Escherichia coli (strain K12)
Function: Putative thioesterase. Does not bind pectin, and has no pectinesterase activity.
Subcellular location: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- UPF0098 protein YbhB
- Ribonuclease I
- Putative colanic acid biosynthesis glycosyl transferase WcaC
- DNA gyrase inhibitor
- Transcriptional activator protein BglJ
Sequence:
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
Protein: Protein ETHYLENE-INSENSITIVE 3-like 1b (EIN3-like protein 1b) (OsEIL1b) (OsEIL1) (Q8W3M0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor acting as a positive regulator in the ethylene response pathway. Involved in wound signaling by binding specifically to the DNA sequence 5'-ATGTACCT-3' found in the promoter of some wound-inducible genes. Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein ETHYLENE-INSENSITIVE 2
- Os02g0200900 protein.
- Os06g0605900 protein
- Mitogen-activated protein kinase 5
- Mitogen-activated protein kinase 1
- AP2 domain containing protein, expressed
- Os09g0572000 protein
- Os07g0156732 protein
- Transcription factor MYC2
- Natural resistance-associated macrophage protein, expressed
Sequence:
MMGGGLVMDQGMMFPGVHNFVDLLQQNGGDKNLGFGALVPQTSSGEQCVMGEGDLVDPPPESFPDAGEDDSDDDVEDIEELERRMWRDRMKLKRLKELQLSRGKDPAGGVVGDPSKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPVSGASDNLRGWWKEKVRFDRNGPAAIAKYQADNAVPGFESELASGTGSPHSLQELQDTTLGSLLSALMQHCDPPQRRYPLEKGVPPPWWPTGDEEWWPELGIPKDQGPPPYKKPHDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELYLKLNPGARPPAPTGGITSAISFNASSSEYDVDVVDDCKGDEAGNQKAVVVADPTAFNLGAAMLNDKFLMPASMKEEATDVEFIQKRSASGAEPELMLNNRVYTCHNVQCPHSDYGYGFLDRNARNSHQYTCKYNDPLQQSTENKPSPPAIFPATYNTPNQALNNLDFGLPMDGQRSITELMNMYDNNFVANKNLSNDNATIMERPNAVNPRIQIEEGFFGQGSGIGGSNGGVFEDVNGMMQQPQQTTPAQQQFFIRDDTPFGNQMGDINGASEFRFGSGFNMSGAVEYPGAMQGQQKNDGASEFEELE
Protein: LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4) (P61969)
Organism: Mus musculus (Mouse)
Function: Transcription cofactor. Plays a role in establishing motor neuron identity, in concert with MNX1, acting, at least in part, to disrupt LDB1-LHX3 complexes thereby negatively modulating interneuron genes in motor neurons.
Interaction partners:
- LIM domain-binding protein 1
Sequence:
MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
Protein: Altered inheritance of mitochondria protein 39, mitochondrial (Q08223)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein FMP25, mitochondrial
- Large ribosomal subunit protein uL2m
Sequence:
MWGLCKKHFPSNKIQVQERNKALKPKKSGSEHKTKQLFPVFNCKKKEKGVMIRFAILRNANTSLLSARSICLFTQAPTYCHVRLNTLNKSITTKRNSLTESKRHVHDGKHFFTTPHQQQQTKLGEIEEGHSPNIKGEDLRSIGQAITHQRNKRRKQIWSAIFGGIFGVILGYSLIYRVIYLKEQSFLPLFPSSKIRKLSTRDLKKVDVNQVQKLSKLRVLEILSGHDMIKEQYGVPLLDKDGNSPTLNEFSMWCEDQDPCVTGIVMEPDDKRDSSHTWYRIPFVCKWRITHRPISIRGTIDDLLNRIGLETADLFEIISPERVYGSFKYEYPLQGDSHALHLWFHGEIELDDDSLIVYNGKYHVDVKLQEIDLFRREKNGQLIQYVLYKNEAGDK
Protein: Cyclic di-GMP phosphodiesterase PdeR (EC 3.1.4.52) (P77334)
Organism: Escherichia coli (strain K12)
Function: Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two cyclic-di-GMP (c-di-GMP) control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA and expression of the master biofilm regulator csgD. PdeR acts as a trigger enzyme that connects modules I and II. It inhibits DgcM and MlrA by direct interaction. Inhibition is relieved when PdeR binds and degrades c-di-GMP generated by module I.
Interaction partners:
- Cyclic di-GMP phosphodiesterase PdeH
- HTH-type transcriptional regulator MlrA
- Diguanylate cyclase DgcM
- Probable diguanylate cyclase DgcE
- Probable diguanylate cyclase DgcQ
- Probable diguanylate cyclase DgcJ
- Signal transduction histidine-protein kinase BarA
- Aerobic respiration control sensor protein ArcB
- CsgBAC operon transcriptional regulatory protein
- Beta-galactosidase
Sequence:
MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPDRTLQLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWAGNASAWHDTPAVARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLFMSRREAAASRRNNRVFFRSGNAYEVELWIPTCKGQRLFLFRNKFVHSGSGKNEIFLICSGTDITEERRAQERLRILANTDSITGLPNRNAMQDLIDHAINHADNNKVGVVYLDLDNFKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMASRILTRLRLPFRIGLIEVYTSCSVGIALSPEHGSDSTAIIRHADTAMYTAKEGGRGQFCVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPERGLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQTIFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKEDAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA
Protein: Uso5p (A0A1D8PJR1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Kinesin-like protein
Sequence:
MTTPSYTKNLNMNTKSSKEQTRSKRPLSEISPNLRRDPLKKRRNSLGFEMASIPSNSIKSFPSRIPPPTASKSATIASSSSSSSSSSMSSLSSIPQGILSIQERLRRKASVNDNNGQSSSSFAARPQSTVSRSNELQEEYYSLNELYKQQASSYEKLEVELGKLKEIYKNYYYKIDLINDLVHQKQSEFEILEHDIINDVEQEEKLTYSKLHENKIKLDGQFKELEFEMLNQLEDAKQFDFKELLTKIESLKTEKMTVLSEYEKVMSEVNAKLNADREQFSKDLEDKLHPLNKNKQLINDQLINKKDELTKLETNYNELKDQLAERNDSIDSIKHEIANIEQEMNNYQATRKNLELKLSEAESELHEALAKDKQEQREYDNVRSEYSVLHSKIAKHDEHRRILENSIMKIQGKFRVYAIGEDLDTYNKCFAKDTPSSFIIDEFQCLVQSTLKGHNVAIINNYLRGSQIVIDSYKNIQRQQKYIYQCISIKNGDKNTDICDLLNSNAPVDSLFQHQQMVIDDFDQFKQIVKKIDATLSQEIAIHIISTDKSKLMIIDCSRIDPDQQDKILEKFKSNSSLGFLEKLLTWIYHNCSTLFLYEPKTSQSNSLLKFINSIDSPI
Protein: D-galactonate dehydratase family member RspA (EC 4.2.1.-) (D-gluconate dehydratase) (EC 4.2.1.39) (Starvation sensing protein RspA homolog) (D4GJ14)
Organism: Pantoea ananatis (strain LMG 20103)
Function: Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).
Interaction partners:
- Mannonate dehydratase
- YdfI
- YdfI
- UxaA
- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
- 2-dehydro-3-deoxygluconokinase
- KdgK
- 6-phosphogluconate dehydrogenase, decarboxylating
- YqeC
- Ribulose-phosphate 3-epimerase
Sequence:
MSNLFITNVKTILTAPGGIDLVVVKIETNEPGLYGLGCATFTQRIYAVQSAIDEYLAPFLIGKDPARIEDIWQSAAVSGYWRNGPVMNNALSGIDMALWDIKGKQAGLPVYELLGGKCRDGIALYVHTDGADEVEVEDSARAKMEEGYQYIRCQMGMYGGAGTDDLRLIANRMVKAKNIQPKRSPRTKAPGIYFDPEAYAKSIPRLFDHLRNKLGFSVELLHDAHERITPINAIHMAKALEPYQLFFLEDPVAPENTEWLKMLRQQSSTPIAMGELFVNVNEWKPLIDNKLIDYIRCHISSIGGITPAKKIAIYSELNGVRTAWHSPGDISPIGVCANMHLDLSSPNFGIQEYTPMNDALREVFPGCPEVDQGYAYVNDKPGLGIDINEALAAKFPCEGGNPTWTMARTPDGTVWRP
Protein: Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein) (Q8N2F6)
Organism: Homo sapiens (Human)
Function: May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12839973}; Single-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion outer membrane {ECO:0000269|PubMed:27184847}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAGALEEGTSEGQLCGRSARPQTGGTWESQWSKTSQPEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI
Protein: Y-box-binding protein 2 (FRGY2 homolog) (Germ cell-specific Y-box-binding protein) (Q9Z2C8)
Organism: Mus musculus (Mouse)
Function: Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11566752}. Nucleus {ECO:0000269|PubMed:11566752}.
Interaction partners:
- Homeobox protein NOBOX
Sequence:
MSEAEASVVATAAPAATVPATAAGVVAVVVPVPAGEPQKAGGGAGGGGGAASGPAAGTPLHAPGPRTPGNQATAASGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGARAANVTGPGGVPVKGSRYAPNRRRFRRFIPRPRPAAPPPMVAEAPSGGTEPGSEGERAEDSGQRPRRRRPPPFFYRRRFVRGPRPPNQQQPIEGSDGVEPKETAPLEGDQQQGDERVPPPRFRPRYRRPFRPRPPQQPTTEGGDGETKPSQGPTDGSRPEPQRPRNRPYFQRRRQQPPGPRQPIAAETSAPINSGDPPTTILE
Protein: Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC) (Q3SZE9)
Organism: Bos taurus (Bovine)
Function: Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
Subcellular location: Cytoplasm {ECO:0000250}. Note=Detected predominantly in the photoreceptor connecting cilium. {ECO:0000250}.
Interaction partners:
- Tubulin-specific chaperone D
- Tubulin-specific chaperone cofactor E-like protein
- Tubulin-specific chaperone E
- Tubulin-folding cofactor B
- ADP-ribosylation factor-like protein 3
- Tubulin-specific chaperone A
Sequence:
METGGLSAAALANGDLGSQRERTLVPERLQKREHERQLEVERRKQKRQDQEVEEEKSDFFAAAFARERSAVEELLESGESVERLEEAAARLQGLQKLINDSVLFLAAYDLRQAQEVLARLQAALAKRRQELQPKKRFAFKTRKKDAASATQVASAPDAPAAEGSLTSPPPLKEEGDFDSSWICGFSNLQSQVLEKRAEELHQQDVLLTQLRNCTIKLYGNPNTLRLTKAQGCTLLCGPVSTSVFLEDCSDCVLAVACQQLRVHTTKDTRIFLQVTSRAIMEDCTGIQFAPYTWSYPGIDKDFEGSGLDKNKNNWNDVDDFNWLARDVASPNWNVLPEEERRIQWD
Protein: E3 ubiquitin-protein ligase DA2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase DA2) (Q93YV5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase involved in the regulation of organ and seed size. Acts synergistically with DA1 to regulate seed size. Functions synergistically with DA1 to restrict cell proliferation in the maternal integuments of ovules and developing seeds. Seems to function independently of BB. Possesses E3 ubiquitin-protein ligase activity in vitro. Polyubiquitinates DA1, DAR1 and DAR2, but not DAR3.
Interaction partners:
- E3 ubiquitin-protein ligase BIG BROTHER
- Ubiquitin carboxyl-terminal hydrolase 15
- Protein SDA1
- Protein SDA1
- At1g75700
- Transcription initiation factor IIF, beta subunit
- E3 ubiquitin ligase BIG BROTHER-related
- Protein DA1-related 1
- Cytochrome P450 78A5
- Protein DA1-related 2
Sequence:
MGNKLGRKRQVVEERYTKPQGLYVNKDVDVKKLRKLIVESKLAPCYPGDDESCHDLEECPICFLYYPSLNRSRCCMKSICTECFLQMKNPNSARPTQCPFCKTPNYAVEYRGVKSKEEKGIEQVEEQRVIEAKIRMRQKEMQDDEEKMQKRLESCSSSTSAMTGEMEYGSTSAISYNSLMDDGEIAPSQNASVVRQHSRPRGNREDEVDVDLEELMVMEAIWLSVQETGTQRNSASGEITSSRQYVTDNHSYVSSPPRVTPIVEPATPSSSSGGLSCAISALAERQMVGESSSHNHNHNVNVSSYSMLPGNCDSYYDIEQEVDGIDNHHHHRHHYEMGETGSSNSYVSSYMTGEGFHNFPPPPPLVIVPESFEEQMMMAMAVSMAEVHATTTCAPTEVTWQ
Protein: Catenin beta 1 S homeolog isoform X2 (Ctnnb1 protein) (A1A5I6)
Organism: Xenopus laevis (African clawed frog)
Interaction partners:
Sequence:
MATQDLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEDDDVDPNQVLYEWEQGFTQSFTQDQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDSAHPTNVQRLTEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCAAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYSYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDSSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMPWNEAADLGLDIGAQGEPLGYRQDDPGYRSFHAPGYGQDAMGMDSMMDHDMGGHHPGADYPVDGLPDLSHAQDLMDGLPPGDSNQLAWFDTDL
Protein: GH05223p (Q7YTY8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000256|ARBA:ARBA00004212}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004212}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MARNVQQRQQHPCTTTEEPKHQRARGTAGHQESATGECQQFWSKQRPPFDQQQQQEDQDPEQDPQQHPSTPQESVHHHRSPRQHELLHHQRKVPPTLPARGRHLISEGARRREVRGCGAGGGGLLCCSLDALSRPAKLLQFGVLLLILLLATHGDLAQAEGNVGCQFVRTLCIPHSEVCYDDNIFGKCIPTTGVDVEDIEKTPLTEDQSRVLATMLEELQGAGLGWDHPYVQCRIQGSLFSLQRQQQLPPNLCANLAPTPPEFGDPASALAYVRFTPPEPEAELDYYEQPAGPAQFYPALRKKQVRESDADDMYLNRMLQDRRRLRHDPSELEHFGKMDGHGQSTQLDAPSIMDAFLDTERQRIEREQQLAAAEQDADRRAEQNRLELYQILAASEPDPQPYQRKPAAQPNAMDQLEAIVEQQQQRELKEQQEQAKAPVYVPPEEVNESSELYFPDNFAPFKRARGRSRGGLAEEVEDEQPKRSFFRELAGEQGLVQEPPLRFRHVETEVDATPELVKRRPASFKQLDPYDVSLQQQEMAFESGLLRNSLTPLEEEAMLASNSFPRQAKSQRVYTEGGLLLMPQDEQDTDGMQADEPENVKQSLLANMLGFARHERLDVKKPGPLLGPPSLGSAELSNQLETEKAHKQKGHGNKEVLPAHIKGNDEDDAHKKKKVMKQQHSAEDHAPHTVDTEYVHVFVKNPIDSWNDGQRIMKELEQILHMQGYFSYLTVQQHEVSFRVNSNNPERKTAGDVARTINENRGVKNNIQRRVGFYVLHAGVGDVIKDLQDPSVSSSRIELAEQGPDVTHIMAYMFAGAGAAAVIVIFVTLILIKRHDRKRDKLGGLQSGIAGAETCSKDYQELCRARMAGKAGGGGNSTGGAAGGGSNEPAPSGRITSLSKENEGRPPSSRSSTSSWSEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPANTSGEKRELDKDPVVGGGSSSTTTKEPLKEDKAQEAAEEEAPTSSSKAAAAAKKEKEGITGGGWSFACR
Protein: Protein PAT1 homolog 2 (PAT1-like protein 2) (Protein P100) (Protein PAT1 homolog a) (Pat1a) (XPat1a) (Q4V7K4)
Organism: Xenopus laevis (African clawed frog)
Function: RNA-binding protein that acts as a translational repressor. When overexpressed, able to disperse P-bodies.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:1606954}. Nucleus {ECO:0000269|PubMed:20826699}.
Interaction partners:
Sequence:
MNLGSEQILPEDFYLAEEGALLEEMAEEDEEIDLYNEVTFGLDQESDEEPVKLEDDHTKPIQMPEAPKEEEPEALQPVKEAKGSEKAPLHEVKIVVEPHEDHVDLSIDSGGHTMNSTMDDSELGDPAVMKAFHGKPTLESLDSAVVDSGIGSTWSELDTDYDQSGMDSGLWEASPKVSTYATGQILEDKAILRIMERAPYLPPTNLEFLGSPLQRGFMPSQRLQGPEMGAMSPKPYRPRFMRQQSPLVPRSMRPSYPFTPPRRGPSVFAPNQSPGFVSQTPFRPMSPNVSTPTRPMTPKMVRMHFGPMSPSPSFSPFFSPMGNALQRFKVPGHVTQLHPQHRRILSQRQRPQSSSRRQWESRPDPYASLMSQKEKEWVIKLQMIQLQSENPHLDDYYYQAYYENLERKLSEEEFLGERKKREPTKLVTPYIQKAETYESVVHIEGSLGQVAVSTCYSPRRAIDAVSYAMPDEAIKALGYQRLRVLKHAEKVFLMFLEVEELARKMSHIPEEEHVHFQHKQNYKVQRIYDVLKIAPCHNEEESEFLQLLQVGKGKKLVARLLPFLRSEQAREILLLVVQHLTFLIKNDSAEESLSVLYGPLKTIINGLSFTELIGVTQELTRPLPESNDLPLTLAFQNQFGISLLYCLLSHGERLLSSDLPMEPCIGDFEKWTDTVFLVAKELSHVSKSSMVEPLFLPSNLLSLFCRYLDKQTIHKLEDKMECPVIPPYTAVPS
Protein: DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (P97304)
Organism: Mus musculus (Mouse)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P0DPB6}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P0DPB6}.
Interaction partners:
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerase I subunit RPA12
- DNA-directed RNA polymerase I subunit RPA1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase I subunit RPA34
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase I subunit RPA2
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase I subunit RPA49
Sequence:
MEDDQELERKISGLKTSMAEGERKTALEMVQAAGTDRQCVTFVLHEEDHTLGNCLRYIIMKNPEVEFCGYTTTHPSESKINLRIQTRGALPAVEPFQKGLNELLNVCQHVLVKFEASIKDYKAKKASKKEPTF
Protein: Pentatricopeptide repeat-containing protein At1g62670, mitochondrial (Q9SXD1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Ribosome production factor 2 homolog
- Probable disease resistance protein At1g15890
- Ribosome biogenesis regulatory protein homolog
- R3H domain protein
- NADH-ubiquinone oxidoreductase chain 6
- NADH-ubiquinone oxidoreductase chain 6
- Uncharacterized mitochondrial protein AtMg01280
- NADH dehydrogenase subunit 9
- NADH dehydrogenase iron-sulfur protein 3
- Pentatricopeptide repeat-containing protein At4g21190
Sequence:
MRISFAIASTAKRFVHRSLVVRGNAATVSPSFSFFWRRAFSGKTSYDYREKLSRNGLSELKLDDAVALFGEMVKSRPFPSIIEFSKLLSAIAKMNKFDVVISLGEQMQNLGIPHNHYTYSILINCFCRRSQLPLALAVLGKMMKLGYEPNIVTLSSLLNGYCHSKRISEAVALVDQMFVTGYQPNTVTFNTLIHGLFLHNKASEAMALIDRMVAKGCQPDLVTYGVVVNGLCKRGDTDLAFNLLNKMEQGKLEPGVLIYNTIIDGLCKYKHMDDALNLFKEMETKGIRPNVVTYSSLISCLCNYGRWSDASRLLSDMIERKINPDVFTFSALIDAFVKEGKLVEAEKLYDEMVKRSIDPSIVTYSSLINGFCMHDRLDEAKQMFEFMVSKHCFPDVVTYNTLIKGFCKYKRVEEGMEVFREMSQRGLVGNTVTYNILIQGLFQAGDCDMAQEIFKEMVSDGVPPNIMTYNTLLDGLCKNGKLEKAMVVFEYLQRSKMEPTIYTYNIMIEGMCKAGKVEDGWDLFCNLSLKGVKPDVVAYNTMISGFCRKGSKEEADALFKEMKEDGTLPNSGCYNTLIRARLRDGDREASAELIKEMRSCGFAGDASTIGLVTNMLHDGRLDKSFLDMLS