wanglab/gogpt-training-data huggingface dataset:
Protein: Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5) (O43294)
Organism: Homo sapiens (Human)
Function: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.
Subcellular location: Cell junction, focal adhesion. Nucleus matrix. Cytoplasm, cytoskeleton. Note=Associated with the actin cytoskeleton; colocalizes with stress fibers.
Interaction partners:
- Protein-tyrosine kinase 2-beta
- Vinculin
- Androgen receptor
- Focal adhesion kinase 1
- TNF receptor-associated factor 4
- Neutrophil cytosol factor 1
- ARF GTPase-activating protein GIT1
- Mothers against decapentaplegic homolog 3
- Talin-2
- Talin-1
Sequence:
MEDLDALLSDLETTTSHMPRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG
Protein: Polypyrimidine tract-binding protein homolog 3 (Q6ICX4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in pre-mRNA splicing. Binds to the polypyrimidine tract of introns. May promote the binding of U2 snRNP to pre-mRNA (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Translationally controlled tumor protein 2
- Large ribosomal subunit protein eL18x
- At3g52060
- Nuclear cap-binding protein subunit 2
- Serine/arginine-rich splicing factor SC35
- RNA-binding
Sequence:
MAESSKVVHVRNVGHEISENDLLQLFQPFGVITKLVMLRAKNQALLQMQDVSSAVSALQFFTNVQPTIRGRNVYVQFSSHQELTTIEQNIHGREDEPNRILLVTIHHMLYPITVDVLHQVFSPYGFVEKLVTFQKSAGFQALIQYQVQQCAASARTALQGRNIYDGCCQLDIQFSNLEELQVNYNNDRSRDYTNPNLPAEQKGRSSHPCYGDTGVAYPQMANTSAIAAAFGGGLPPGITGTNDRCTVLVSNLNADSIDEDKLFNLFSLYGNIVRIKLLRNKPDHALVQMGDGFQAELAVHFLKGAMLFGKRLEVNFSKHPNITPGTDSHDYVNSNLNRFNRNAAKNYRYCCSPTKMIHLSTLPQDVTEEEVMNHVQEHGAVVNTKVFEMNGKKQALVQFENEEEAAEALVCKHATSLGGSIIRISFSQLQTI
Protein: EPM2A glucan phosphatase, laforin (A0A1W2PPT8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEDEKRTADMCCSGMWEETAGQILRGGRKWTKTNIQKGPMLWIL
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Q5ZIP0)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MALALPEPPWPASLTPLKAVDDLLRCGICFDYFSIAVIIPQCSHNYCSLCIRKFLSYKTQCPTCCVAVSESDLKNNRTLDELVKSFSSARQQLVQLVLDTPLISSPLACSRRSIGKNHSKTPASLPVVKEEVPVIDSFLKKENVCTLTKTDGLAGTDWKVCKTEEHHSSSSSSPEAGSKDNKAGSRECSEGTNSGEKPSTSVVKVVNKVDCPVCGVAIPEEYINKHLDSCLSREEKKDCLRSSAHKRKPMPKVVYNLLSDRDLKKKLKEHGLSSHGSRQQLIKRHQEFVHVYNAQCDSLNPKSVAEIVKELAKNEKIRVQLELNKSGENSLTFTKDQTEEEIDEIHTSYRNKHRSEFQFLVDQVKNRWEKSGKRETESTQKKKEGTAIGLPAGTGEGPEEHRSAAVLGEAQVLKPGTPDGKRSDPRSSEEGQGSVSLAFSDSSGSSSSSSSDILRDLEAEICSVSSDSNCLLDLKASKRKVCQSELSGGDRLLPRSKRKKS
Protein: Lutropin-choriogonadotropic hormone receptor (LH/CG-R) (Luteinizing hormone receptor) (LSH-R) (P16235)
Organism: Rattus norvegicus (Rat)
Function: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P22888}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P22888}. Secreted. Note=Some isoforms may be secreted.
Interaction partners:
- Glycoprotein hormones alpha chain
- Lutropin subunit beta
- Follitropin subunit beta
- Pro-opiomelanocortin
- Pro-glucagon
- Natriuretic peptides A
- Gastric inhibitory polypeptide
- VIP peptides
- Cholesterol side-chain cleavage enzyme, mitochondrial
- Pituitary adenylate cyclase-activating polypeptide
Sequence:
MGRRVPALRQLLVLAVLLLKPSQLQSRELSGSRCPEPCDCAPDGALRCPGPRAGLARLSLTYLPVKVIPSQAFRGLNEVVKIEISQSDSLERIEANAFDNLLNLSELLIQNTKNLLYIEPGAFTNLPRLKYLSICNTGIRTLPDVTKISSSEFNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLISLELKENIYLEKMHSGAFQGATGPSILDISSTKLQALPSHGLESIQTLIALSSYSLKTLPSKEKFTSLLVATLTYPSHCCAFRNLPKKEQNFSFSIFENFSKQCESTVRKADNETLYSAIFEENELSGWDYDYGFCSPKTLQCAPEPDAFNPCEDIMGYAFLRVLIWLINILAIFGNLTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCGAAGFFTVFASELSVYTLTVITLERWHTITYAVQLDQKLRLRHAIPIMLGGWLFSTLIATMPLVGISNYMKVSICLPMDVESTLSQVYILSILILNVVAFVVICACYIRIYFAVQNPELTAPNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFLLLLSRFGCCKRRAELYRRKEFSAYTSNCKNGFPGASKPSQATLKLSTVHCQQPIPPRALTH
Protein: Aflatoxin B1 aldehyde reductase member 3 (AFB1-AR) (EC 1.-.-.-) (Aflatoxin B1 aldehyde reductase member 1) (rAFAR1) (P38918)
Organism: Rattus norvegicus (Rat)
Function: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. Probably involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Subcellular location: Cytoplasm.
Interaction partners:
- Aflatoxin B1 aldehyde reductase member 2
- Aldo-keto reductase family 1 member A1
- aldose reductase
- Aldo-keto reductase family 1 member B7
- Aldo-keto reductase family 1 member B1
- Glutathione S-transferase alpha-5
- Aldo-keto reductase family 1, member C1
Sequence:
MSQARPATVLGAMEMGRRMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATKAAPMFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFPDHGTPIEETLQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFSQLYMDRYWKEEHFNGIALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNLALVEEGPLEPAVVDAFDQAWNLVAHECPNYFR
Protein: Small ribosomal subunit protein uS8A (40S ribosomal protein S22-A) (RP50) (S24) (YP58) (YS22) (P0C0W1)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22096102}.
Interaction partners:
- Large ribosomal subunit protein uL3
- Small ribosomal subunit protein uS4A
- Small ribosomal subunit protein eS7A
- Small ribosomal subunit protein uS17A
- Periodic tryptophan protein 2
- Large ribosomal subunit protein eL30
- Small ribosomal subunit protein eS26B
- Small ribosomal subunit protein eS17A
- Ubiquitin-ribosomal protein eS31 fusion protein
- Small ribosomal subunit protein uS19
Sequence:
MTRSSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY
Protein: Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.-) (Q54E42)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2
- Major vault protein beta
- Major vault protein alpha
- Poly [ADP-ribose] polymerase
Sequence:
MATSIKRGDPQSEKIKYIKGTFFVIRPDETSKEPFWIAYALEDVPAKNKEVYVRWLTVSDEDETEYKVGPESSSSNIPIESIIVTTTLKANSKQESSYRISKIELRRVNTIVENESSSEEEEEEESNGEEEKEGNAQESGSESEESESESEVPVKKTKKQLVEEQKKSAAAAKKLQKEKEKEKEKEKAKKLKEKEKEKEKAKKQKEKEKEKAKKLKEKEKEKKKKNSESEKPKKSNKSKKQEDTENESESESESESESSSSESEKEESSKKSSSKKKTTTKEKSKPTKKSKKQETEDEEESGSDESSGDDDEKSSSDEDEREKKSSKKSSTAANGKPQEIKPIVKKSTGKRKKNEDSDASSGDEEEEEEDKTTTKKSKGKGGESKKVVKEKVTKVAKPTKASIKAQTKKGNPNPAIPVLEVDPGFEWAKTATTLSDFCCSICRSREASKAIIENNIPLLKEIIKENRYNSLLSNWSSGLEKSPLHYAIINNNIEAIELVYKDAKDEAKLRPSLPNFDKASTGTYSKYTYGHNVRALTQSRGGKEGDEAFLHDSNNYQEHELTLEVQQTNIIQLIFSNSCVKMTTIQELFRLDPTLNDNVSYNIYYAVRAGNLEVSEHFVKDLFKRGGFGFNNLHSQALSVDGNEEFLPFKSVSVTKKPNFGNVTPIHFAAINPKGKYLKQLLDVLSEPSRPDHNSFRPLHYAAACTAPVNIQLLTSKGVELNDLNSLGMTPLMIASQLGRVQNIKALVKASKERQIVNFVKFKNKKLQDALHFAAEAGQLGSIRTLLEEGADIDVFEKGTKYTALMKASIMGHFDAVKILVEEGKADVEKKDKFKRTALVLAAINGHIKIVSFLLHYNASFKVIDSSKNSILHFTAAYGWIDIIRYLVEQFQAPINEFNDWKTTPLSVAIRKGHFQCTKYLLDKDADANVTDENNRSILLQSLVNSSLSMALMENIKYLIVQGKANVNHQDKDLNGVLHVLSLAEIELPGEVKEKQPNYYWGRQAKPAEDPVKAEKRLQDQLKIVEEIANYLISKGASVNSKNKDGCTPLMLAFQEKNIPIIIYLLGRSDVSLVGTYSSTKSNILHDIMKLDDSLHFSKITDLLLKSKDLKTIINQYNKEHLTPLMSIIKNFKSDTTEKNEKFFKFLRSLISNAKPDLSLVEEKLVIDADSMDESDDHHNTSNISHNSSDDDNSDNGSDDDDNLDDDDDNSDGNSDNDDDNNSDNEEHGKNKDDKELILKRSVLHFAVQTGSLNIVQILLEFKPKDIDQLNVYSETALHNAIDGNHFQIAFLLVDSGANVKISNSFERSPLHLACAKMNFPLIKKLASKGSPINKQDFKGLTPLMIACQNKGNISDEALEGEDNPISILLQNGADPKIVDSKKRNALHYSINASGADTNSSFEIEDLLIKHKAPLNEVDYLGRTPLHYAFIKIGSRFIDNGTSYDPVQVVSSLCSFESIQIDKPDKFGRSPLFYACQHGSTVSALLLIQRKADINRVDEDGNTPLAITLLFKHPDCAINVIQKGANVKGTLTKFNYKITKTETPWKTETTTTTTTPNGATTTTTTTTTTTTTASTSTTASANILPQVAAPLNRGRISRAQHSNAAIQEPKIPHYKQPMKVEYKVEKINVCKVGLFYHVVSNNWQGVAYIMLDSGLDNFSALHDAFKADKYQLALTLLSKCRSAAELSPLSPESKQNLFHFIGMYPSSVANWSARVQQKLLSSGVSPNLTDSTGRTPLHYAAVSENVPFTQFLLTQKLNINQQDKEGNTPLSLALIKIKTPTPITSDTQQQQSTEDIIKNFVLPAEFKLLLTNLPNLELKFKYEENEITPLIYAINIKNIGLIGTLLNSKANINTVDALGQPPLFHAVKTNKMDIVNLILSKKPNMNIQDTDKKSVIHYVVNPTEYGSFENVTLLNLLAKQGSKIDLADIAGKTPLYYASLQDSGKMKDALIKLGAKKIPQETLPTREVSTISNWSELNTVNYEQDYNKYIETKKELMAASNKQLKPLVDPISRMQENSEVYVDSNGLIFDILMTKVDAKRGNWGENNFYKMQIIYNPGLDRYFLWNRWGRIGDVGQYQKTPFSKDEAVTEFCKVFKTKSGNAFNLDSMSNFQKIEGRYHLVHIDRTDKTKKEILHPFVLSQYPKSQLPKELYDVMAQFCNVESISHQLKNLKIDTDIMPLGRISKDLIQKAITVLGKLSEAVEQIRLIEEHEANKRASSFTNATTVGSGVSGSGGDSTSTTDKPEEPNFPPLNDVKESLIKLSNEFYELIPHSNFSTERMVILKSAKEITAKTTLLQNLDELETVSKILIAAHQNTTMHPYDYCFKALGASLEKLDANSPEFGILKKYSENTGCTKKIVNIFKLQRKGEVERFQAHKNLKNHFLLWHGSLTTNYLSILSQGLKIAPPEAPVTGYMFGKGIYFSDMFRKSINYCGSWDSSSANSFLLLSEVALGTMKEFKSAHYMESPETGTNSTKGVGKTGPNFDDSIILNNGVAIPLSPPEQVKGDTSDYHLEMNEYIVYDVSQIRMRYLVEVSN
Protein: Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Q8VHI4)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:11832226}.
Interaction partners:
Sequence:
MEQRHSLAGNCDDGEKSEREAQGFEHRTCMDSGDPSFGQNDPPTILPITAPKTYDSLTSQDMPETLTDTQALHEEQFHLLDQNGQPIQYDLQSLGNSTAQMTGMEQVAIPQEPFADEHSPQDISEEKPTGVRADVLEDSTSNYGLRSPASLVLPKKAGARLVEEPLLAPLQPLSCNTPMWACRLRSCEKIGDSYRGYCVSETELESVLTFHKQQTQTVWGTRQSPSPAKPATRLMWKSQYVPYDGIPFVNAGSRAVVMECQYGPRRKGFQLKKISEQESRSCHLYKATCPARIYIKKVQKFPEYRVPTDPQIDRKIIRLEQEKAFTMLKKNLMDAGGVLRWYVQLPTQQAHQYHESETPGVPLSPSPFPMSPLEEEEAIVRDENCALPSRLHPQVAHKIQELVSQGVGQVYAVRKQLRKFVERELFKPDEIPERHNLSYFPTVNDIKNHIHEVQKSLRTGDVVYNSEIIPATLQWTTDSGNILRETVTVTFAEGNLLGEPIPSKMGTSQTQTAVSPEPLSSFPPKIFTHFQALKLQPRLSSPDGSQALVSVDSHASSSPPGLVDTVGNAEVDNHSVLLGQSQNPGTDTCLTQDNSTSSSTGHLPESVPNPVAEDQLLEGEDVEDAGNPEGSVNRTLLGDVQTVPIQIIDSRPVLVEESLSKNQVKQETNEPTLSTEAKTFLDCKKISAT
Protein: Protein SODIUM POTASSIUM ROOT DEFECTIVE 1 (NaKR1) (Heavy metal-associated plant protein 2) (AtHPP02) (Nuclear-enriched phloem companion cell gene 6) (NPCC6) (Q8LDS4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for root meristem maintenance after germination. Involved in phloem translocation, starch accumulation and flowering. Promotes flowering in the photoperiod pathway. Regulates long-distance movement of FT from leaves to the shoot apex through the phloem stream.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21193571}. Nucleus {ECO:0000269|PubMed:21193571, ECO:0000269|PubMed:27255839}. Endoplasmic reticulum {ECO:0000269|PubMed:27255839}. Note=Mobile through plasmodesmata. {ECO:0000269|PubMed:21193571}.
Interaction partners:
- FT-interacting protein 1
- Protein QUIRKY
Sequence:
MLCASQASTTTLCSTMDQTSQPSSSSSATIRLGGRAIDRHNPIIRDGRRLTPPPSPNLNPSSSSSSTYHTPLMTRLGLESSEQKRLAKRKSKKGDSDVGKSPVSCFSSDTPQGSSRYLLSNPVFFDGFVDSDPIPIPIDEPEITKADDLNNFHEDRLIINASKYLSTSASFLEKKQPDFFEGFLDYEPVLSPDNPFSEPTKASPTASLSSLEDKDVSSPDFKFSPPPPPPPSPPQSSPPSPPEKNSSSDQVVVLRVSLHCKGCAGKVKKHLSKLKGVTSYNIDFAAKKVTVTGDVTPLTVLASISKVKNAQFWPEIIQK
Protein: A-type ATP synthase subunit B (A8AAA9)
Organism: Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)
Function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
Subcellular location: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00310}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00310}.
Interaction partners:
- Uncharacterized protein
- A-type ATP synthase subunit I
- Vacuolar H+-transporting two-sector ATPase, F subunit
- H+-transporting two-sector ATPase, C subunit
- A-type ATP synthase subunit E
- A-type ATP synthase subunit A
- A-type ATP synthase subunit D
- Inorganic pyrophosphatase
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MAVPSVKGKEYESVSEIRGQLLVVEGVSDAGYGELVDIEMPSGEKRRGIVLETGKGLAVVQVFEGTTGISPAGTKVRFTGRILEMGVSEDMLGRIMNALGEPIDGGAPIKAVEKRNVWGEPINPYAREYPDEFIETGISAIDGMNSLVRGQKLPIFSGSGLPHNKLAAQIARQATVRGEEESFAVVFAAVGIQYDELLFFKKAFEETGAISRTAMFVSLANEPAMMKIVTPRAALTLAEYLAFQKDMHVLVIITDMTNYCEALREISASREEVPSRQGYPGYMYTDLATIYERAGRVKGSKGSITQMPILTMPNDDITHPIPDLTGYITEGQIVLSRDLHNKGIYPPINVLMSLSRLMRDGIGKGKTREDHPDVANQLFAAYSRAVELRGLAAIVGEESLSEVDRKYLRFGEAFEQKFLKQDYYERRTIEQTLDLAWEVLSILPEEELTKIRPEYIKKYHPKYRVKAASQK
Protein: Polyadenylate-binding protein 2 (AtPabN2) (AtPabN3) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 2) (Poly(A)-binding protein II) (PABII) (Q9FJN9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length. Increases the affinity of poly(A) polymerase for RNA. Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation.
Subcellular location: Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:23334891}. Cytoplasm {ECO:0000250|UniProtKB:Q7KNF2}. Note=Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus. {ECO:0000250|UniProtKB:Q7KNF2}.
Interaction partners:
- Polyadenylate-binding protein 3
- Polyadenylate-binding protein 1
- FIP1[V]-like protein
- Nuclear poly
- SAP domain-containing protein
- Regulator of nonsense transcripts UPF2
- Histone deacetylase complex subunit SAP18
- FIP1[III]-like protein
- RNA-binding protein Y14
- Cleavage stimulation factor subunit 77
Sequence:
MEEEEHEVYGGEIPDVGEMDGDMEALNPDLDMAAADDDAVKELDEMKKRLKEMEDEAAALREMQAKVEKEMGAQDPASIAANQAGKEEVDARSVFVGNVDYACTPEEVQQHFQTCGTVHRVTILTDKFGQPKGFAYVEFVEVEAVQEALQLNESELHGRQLKVLQKRTNVPGLKQFRGRRFNPYMGYRFRRPFMSPYMYSPYGYGKAPRFRRPMRYMPYQ
Protein: Down syndrome cell adhesion molecule 1, isoform AJ (Q0E9K3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVNQFYEAEIMTEYVIRGNAAVLKCSIPSFVADFVRVESWIDDEGNVLSFSDNYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIGSVSPKISNSDDLKHVKVKRLLSLSLLCPAQAYPQPISRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVLPSIHPFSFDAEANEGDSVQLTCHVAKGDLPLRIRWTHNGLPLFTHLGVMASKIGERISLLTVESVKAANSGNYSCVASNNAGNVSSSAELLVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: 60S ribosomal protein L39, putative (Q57UJ8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 60S ribosomal protein L5, putative
- Large ribosomal subunit protein eL18
- 40S ribosomal protein S18, putative
- 60S ribosomal protein L19, putative
- 60S ribosomal protein L29
- 40S ribosomal protein S8
- 40S ribosomal protein S16, putative
- Small ribosomal subunit protein uS5
- 40S ribosomal protein S26
- 40S ribosomal protein S15a, putative
Sequence:
MGRFKPLAIKKKYAKKLKQNRPVPYWIRLRTGNRIKWNEKRRHWRRTKLHY
Protein: Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase) (Q9VSY6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By similarity).
Interaction partners:
- Phosphoserine aminotransferase
- Serine hydroxymethyltransferase
- L-serine deaminase
- Cystathionine beta-synthase
- Alanine--glyoxylate aminotransferase
- Trifunctional purine biosynthetic protein adenosine-3
- GH03305p
- serine C-palmitoyltransferase
- Serine palmitoyltransferase 1
- Transcription termination factor 2
Sequence:
MSGSVLSLARPAAATNGHNLLTKQLNCNGNGTTGGAAKTTVASAITPPKQPQLAAKVIQQSQIVCFDVDSTVICEEGIDELAEYCGKGSEVARVTKEAMGGAMTFQDALKIRLNIIRPTQQQVRDFIQERPSTLSKNVKRFVSHLKAEGKQVYLISGGFDCLIAPVANELGIPLKNVYANKMLFDYLGEYDSFDINQPTSRSGGKAEAIALIRKENSDDSLITMIGDGATDLEAVPPANYFIGFGGNVVRPEVYRRAQYYVTDFEQLMGQ
Protein: Fatty acid amide hydrolase (EC 3.5.1.-) (N-acylethanolamine amidohydrolase) (Q0JFH7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the hydrolysis of bioactive endogenous fatty acid amides to their corresponding acids. The hydrolysis of endogenous amidated lipids terminates their participation as lipid mediators in various signaling systems (Probable). Converts a wide range of N-acylethanolamines (NAEs) to their corresponding free fatty acids and ethanolamine.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q7XJJ7}. Cell membrane {ECO:0000250|UniProtKB:Q7XJJ7}.
Interaction partners:
- Glutamyl-tRNA
- Os01g0153400 protein
- Glutamate--tRNA ligase, chloroplastic/mitochondrial
- glutamate--tRNA ligase
- glutamine--tRNA ligase
- Large ribosomal subunit protein eL39x
- Large ribosomal subunit protein eL39z
- Large ribosomal subunit protein eL39y
- Os01g0271200 protein
- Os02g0796900 protein.
Sequence:
MGKPPRAMTPVEEVDLSAVRYQSPSLQAPHLTGFSLRAFVWLMESPLFGRLLTSVLKSQNNITRMLQDTVIPERPMYLPEYPPQEPEQGVLLLGDDRDPVDRVEEALHCLPPYDPSLRWPAGDKPPFLYWKIRDFAHAYRSGITTPSVVAEHIIAGVEEWSNKKPPMPMLVYFNADDLRKQAEASTKRFQQGNPISILDGIFIAIKDDIDCFPYPSKGATTFFDKIRSVEKDAVCVARLRKCGVLFIGKANMHELGLGVTGNNPNYGTARNPHSIDRYTGGSSSGPAALVSSGLCSAAIGTDGGGSVRIPSSLCGIIGLKTTYGRTDMTGALCDCGTVEVASPLAASVEDALLVYSAIAGSRPMDKLTLRPSPLCVPNLVSPDNNNILGSVKIGKYTEWFHDVSDRDISNTCEDALNLLCSSFGCQIEEIILPELEEMRTAHVVSIGTESFCDLNPHYRAGKRTEFTLDTRTSLALFGSFTSTDYVASQRIRRRIMYYHNEAFKKVDVIATPTTGITAPEIPQSSLKLGESNYVVSAYLMRFVIAGNLLGLPAITVPVGHDKQGLPIGLQLIGRPWGEASLLRVASAIEELCLQKRKRPSAFHDILNA
Protein: Abhydrolase domain-containing protein 2 (EC 3.1.1.-) (Q24093)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSTAFLTLIAVIVCILFRILNVHSQPLKPSVWCLDAHFLDCLYKIAPVLREPYIPPRLWGFSGHVQTVLHSIVGRVRCPWPLGERVYMSLKDGSTLTYDLYQPLNEQEDDITVAICPGIANSSESVYIRTFVHLAQCNGYRCAVLNHIGALRSVQVTSTRIFTYGHTEDFAAMVEHLHQKYRQSRIVAVGFSLGGNLVTKYMGEDQKTKPDKVIGGISICQGYNAVEGTKWLLNWQNFRRFYLYIMTENVKSIILRHRHILLSDEVKARHNLNEREIIAAATLPELDEAYTRRVYNFPSTQELYKWSSSLFYFDTIKKPMIFINAKDDPLIPEDLLHPIKEYATTRQNTAYVEVAHGGHLGFYEGGFLYPNPVTWLDRTLVAMVGSLVMMHEVGKVAP
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit) (Q63362)
Organism: Rattus norvegicus (Rat)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q16718}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q16718}; Matrix side {ECO:0000250|UniProtKB:Q16718}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 1.
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 10
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial
- NADH dehydrogenase 1 subunit C2
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
Sequence:
MAGLVKKTTGLVGLAVCDTPHERLTILYTKILDLLKHFPKHAAYRKYTEQITSEKLELVKLEPDVKKLENLLQGGEVEEVILQAEKELSLARKMLQWKPWEPLVEEPPANQWKWPI
Protein: ABSCISIC ACID-INSENSITIVE 5-like protein 8 (bZIP transcription factor 15) (AtbZIP15) (Q9FMM7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Could participate in abscisic acid-regulated gene expression.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Choline transporter-like protein
- VEFS-Box of polycomb protein
- G-box-binding factor 2
- AGAMOUS-like 79
- Basic leucine-zipper 75
- G-box-binding factor 3
Sequence:
MDSYWRLKNLVNDLPVSTSLSRQGSIYSWTVDQFQTSLGLDCGSMNMDELVKHISSAEETQEGSQRQGSTTLPPTLSKQNVGEVWKSITEEKHTNNNGGVTNITHLQGQQTLGEITLEEFFIRAGARGGNTNGGSIHDSSSSISGNPHTSLGVQIQPKAMVSDFMNNMVPRSHDSYLHQNVNGSMSTYQPQQSIMSMPNGYSYGKQIRFSNGSLGSGNQSLQDTKRSLVPSVATIPSEAITCSPVTPFPTLNGKQKINGESSLLSPSPYISNGSTSTRGGKINSEITAEKQFVDKKLRRKIKNRESAARSRARKQAQTMEVEVELENLKKDYEELLKQHVELRKRQMEPGMISLHERPERKLRRTKSDIK