wanglab/gogpt-training-data huggingface dataset:
Protein: Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2) (A2VDL6)
Organism: Bos taurus (Bovine)
Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity).
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit beta
- Sodium/potassium-transporting ATPase subunit beta-2
- Sodium/potassium-transporting ATPase subunit gamma
- Sodium/potassium-transporting ATPase subunit beta-3
- Protein ATP1B4
- Sodium/potassium-transporting ATPase subunit alpha
- cGMP-dependent protein kinase 1
- Mitogen-activated protein kinase
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit alpha
Sequence:
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAFGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVVREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSSILVQGKEIPLDKEMQDAFQNAYLELGGLGERVLGFCQLNLPSAKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
Protein: Ethylene-responsive transcription factor 11 (AtERF11) (Ethylene-responsive element-binding factor 11) (EREBP-11) (Q9C5I3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis-related promoter element. Acts as a transcriptional inhibitor and may regulate other AtERFs (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Probable WRKY transcription factor 40
- AT3G15770 protein
Sequence:
MAPTVKTAAVKTNEGNGVRYRGVRKRPWGRYAAEIRDPFKKSRVWLGTFDTPEEAARAYDKRAIEFRGAKAKTNFPCYNINAHCLSLTQSLSQSSTVESSFPNLNLGSDSVSSRFPFPKIQVKAGMMVFDERSESDSSSVVMDVVRYEGRRVVLDLDLNFPPPPEN
Protein: Ankyrin repeat domain-containing protein 37 (Q569N2)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000269|PubMed:21723927}. Cytoplasm {ECO:0000269|PubMed:21723927}. Note=Present in the cytoplasm of elongating spermatids of the stages IX-X seminiferous tubules while it is localizes to the nucleus of spermatozoa of the stages VII-VIII tubules and mature spermatozoa isolated from epididymis. {ECO:0000269|PubMed:21723927}.
Interaction partners:
- Protein fem-1 homolog B
Sequence:
MLLLSCNLEEDDLKSLLETGASVNAPPDPQEQSPAHLAAGGGLACFLLWQLQTGADLNQQDVLGETPLHKAAKVGSLDCLSLLVASDVQIGVCNKNGQTAEDLAWSYGFPECARFLTMIKCMQTARSSGEQQERDPRAPVLRQKRSFRTVESGVMKRKC
Protein: Cell shape-determining protein MreB (Actin-like MreB protein) (Rod shape-determining protein MreB) (Q01465)
Organism: Bacillus subtilis (strain 168)
Function: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature (By similarity). Filaments rotate around the cell circumference in concert with the cell wall synthesis enzymes. The process is driven by the cell wall synthesis machinery and does not depend on MreB polymerization. The active movement of the MreB cytoskeleton stimulates diffusion of membrane proteins. Organizes peptidoglycan synthesis in the lateral cell wall. Also required for proper chromosome segregation. Membrane fluidity influences MreB movement; in rich medium MreB movement is significantly decreased in a floA-floT mutant.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:11290328}. Note=Membrane-associated (PubMed:15745453, PubMed:17064365). Localizes in the form of helical filaments that encircle the cell (PubMed:11290328, PubMed:15745453). Localization is affected by Mbl, MreBH, MreC and MreD (PubMed:15745453). Colocalizes with MreBH and Mbl (PubMed:16950129, PubMed:17064365). {ECO:0000269|PubMed:11290328, ECO:0000269|PubMed:15745453, ECO:0000269|PubMed:16950129, ECO:0000269|PubMed:17064365}.
Interaction partners:
- Rod shape-determining protein MreD
- Cell shape-determining protein MreC
- Cell division protein FtsZ
- Peptidoglycan glycosyltransferase RodA
- Septum site-determining protein MinC
- Elongation factor Tu
- Penicillin-binding protein 3
- Penicillin-binding protein H
- UDP-N-acetylglucosamine--N-acetylmuramyl-
- Penicillin-binding protein 1A/1B
Sequence:
MFGIGARDLGIDLGTANTLVFVKGKGIVVREPSVVALQTDTKSIVAVGNDAKNMIGRTPGNVVALRPMKDGVIADYETTATMMKYYINQAIKNKGMFARKPYVMVCVPSGITAVEERAVIDATRQAGARDAYPIEEPFAAAIGANLPVWEPTGSMVVDIGGGTTEVAIISLGGIVTSQSIRVAGDEMDDAIINYIRKTYNLMIGDRTAEAIKMEIGSAEAPEESDNMEIRGRDLLTGLPKTIEITGKEISNALRDTVSTIVEAVKSTLEKTPPELAADIMDRGIVLTGGGALLRNLDKVISEETKMPVLIAEDPLDCVAIGTGKALEHIHLFKGKTR
Protein: Megascoliakinin (MBK) (Thr6-bradykinin-Lys-Ala) [Cleaved into: Thr6-bradykinin (Bradykinin-like peptide) (Bradykinin-related peptide)] (P12797)
Organism: Megascolia flavifrons (Garden dagger wasp) (Solitary wasp)
Function: Inhibits ACE with a Ki of 1.6 uM, and targets B2 bradykinin receptor (BDKRB2). Provokes contraction of smooth muscle preparation (ileum). In vivo, induces an early hyperalgesic effects in living rats after intraplantar injection (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:3617088}.
Interaction partners:
Sequence:
RPPGFTPFRKA
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Complex I-B22) (CI-B22) (NADH-ubiquinone oxidoreductase B22 subunit) (Q9CQJ8)
Organism: Mus musculus (Mouse)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:38575788}; Peripheral membrane protein {ECO:0000269|PubMed:38575788}; Matrix side {ECO:0000269|PubMed:38575788}.
Interaction partners:
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase 1 beta subcomplex subunit 4
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
Sequence:
MAFCAPPAYLTHQQKVLRLYKRALRHLESWCIHRDKYRYFACLMRARFEEHKNEKDMMRATQLLREAEEEFWQNQHPQPYIFPDSPGGTSFERYECYKVPEWCLDYWHPSEKAMYPDYFSKREQWKKLRMESWDREVKQLQEETSPDGIMTEALPPARREGDLPPLWWHIVTRPRERPT
Protein: Translation initiation factor 2 subunit gamma (EC 3.6.5.3) (aIF2-gamma) (eIF-2-gamma) (Q8U082)
Organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Function: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
Interaction partners:
- Small ribosomal subunit protein eS28
- Small ribosomal subunit protein uS3
- Translation initiation factor 1A
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein eS19
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein eS4
- Small ribosomal subunit protein uS17
Sequence:
MGEKRKTRQAEVNIGMVGHVDHGKTTLTKALTGVWTDTHSEELRRGITIKIGFADAEIRRCSNCGRYSTSPICPYCGHETEFIRRVSFIDSPGHEALMTTMLAGASLMDGAILVIAANEPCPRPQTREHLMALQIIGQKNIIIAQNKIELVDKEKALENYRQIKEFIKGTVAENAPIIPISALHGANIDVLVKAIEEFIPTPKRDSNKPPKMLVLRSFDVNKPGTPPEKLVGGVLGGSIVQGKLKVGDEIEIRPGVPYEEHGRIKYEPITTEIVSLQAGGQFVEEAYPGGLVGIGTKLDPYLTKGDLMAGNVVGKPGKLPPVWTDLRLEVHLLERVVGTEQELNVEPIKRKEVLLLNVGTARTMGLVTALGKDEIELKLQIPVCAEPGERVAISRQIGSRWRLIGYGIIKE
Protein: DSC E3 ubiquitin ligase complex subunit 2 (Defective for SREBP cleavage protein 2) (Q08232)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the DSC E3 ubiquitin ligase complexes that tags proteins present in Golgi, endosome and vacuole membranes and function in protein homeostasis under non-stress conditions and support a role in protein quality control.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- UBX domain-containing protein 3
- Transmembrane E3 ubiquitin-protein ligase 1
- DSC E3 ubiquitin ligase complex subunit 3
- Ubiquitin fusion degradation protein 1
- Vacuole localized DSC protein 1
- Golgi/endosome-localized DSC protein 1
- UBX domain-containing protein 2
- Nuclear protein localization protein 4
Sequence:
MSMEPPVGLTAMPVTKLAMITTLVVPLVASIASYKHIFLLQYDPFLQTYHQYYRLLIFQFCAINESDTVILALIWYLFRHLERLLGSHKYLTLIVLSWAYTTLGIWGLNLIWNAFIGQYKWLQWNNFSTGSLPIVLSLVHFYKEYTPQIYEWNIRLLGPRGGASSHNDNKREDKSAVEWKINDQFLLNGLILLLILNQGFAGILCGFISWMCGIFIDKGLLPGLDHWRIPFVSYFISQGPPTRANVAIAANAATNTAAARATVEAATAATGNGNTGNSGPTSLPLRGSSTTPTNTSSAGDDEPGADEPARPLGVQFLDTFRR
Protein: Intraflagellar transport protein 46 homolog (Abnormal dye filling protein 6) (Q0G838)
Organism: Caenorhabditis elegans
Function: Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for normal morphology and function of ciliated amphid sensory neurons.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:16648645}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:16648645}. Cell projection, dendrite {ECO:0000269|PubMed:16648645}. Perikaryon {ECO:0000269|PubMed:16648645}. Note=Highly expressed in the transition zones between the cilium basal body and the dendrites. {ECO:0000269|PubMed:16648645}.
Interaction partners:
- Tetratricopeptide repeat protein 30 homolog
- Intraflagellar transport protein 52 C-terminal domain-containing protein
- Intraflagellar transport protein 56 homolog
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport protein 74 homolog
- Intraflagellar transport protein 88 homolog
- Intraflagellar transport protein che-13
- Clusterin-associated protein 1 homolog
- Intraflagellar transport protein osm-1
- TRAF3-interacting protein 1
Sequence:
MSSETTAPMIINEKSSLPVKSEPGQLGNPISDESSEDEQSQIRALEEDQGIYYNEEVVASPKNESDDDIPLRRIQLSHQTSTQQHPEDSEPQEVIDVNDIELPAGEAQPNMERRRSVRFSGRHDEEEDGRNKHFRTPSPESLRYIQALENPMAANGEFEEEFNDLADPQVQPPPMGSPPAYTSADEGPKTPPPRASAGSNMRQESMNELIMRKISDPLQNLIRRASRLEDDSSNDDDDDDDDEDDDYTEDEIAILTYIDAYKTQEVELRPQLRPFTIEYIPAMGDVDLFIKVPRPDEIDDNVGLTQIDEPPSNQSDATIVDMQIRNATKDAAILDDDVPVKLLERADENPDEIKKWISDIKEFHKSKPAQTVHYRTQLPDVETLMQEWPQKLEEVLKTTKIPSAELDVSLEKYVEICLNIVDIPVGKSRIEALHLMFSLLNEFNNSQHFRNLAQNNNLGGETGETMDRLEL
Protein: Probable tRNA methyltransferase 9B (Probable tRNA methyltransferase 9-like protein) (EC 2.1.1.-) (Q9P272)
Organism: Homo sapiens (Human)
Function: May modifie wobble uridines in specific arginine and glutamic acid tRNAs. Acts as a tumor suppressor by promoting the expression of LIN9.
Interaction partners:
- Multifunctional methyltransferase subunit TRM112-like protein
Sequence:
MDHEAAQLEKQHVHNVYESTAPYFSDLQSKAWPRVRQFLQEQKPGSLIADIGCGTGKYLKVNSQVHTVGCDYCGPLVEIARNRGCEAMVCDNLNLPFRDEGFDAIISIGVIHHFSTKQRRIRAIKEMARVLVPGGQLMIYVWAMEQKNRHFEKQDVLVPWNRALCSQLFSESSQSGRKRQCGYPERGHPYHPPCSECSCSVCFKEQCGSKRSHSVGYEPAMARTCFANISKEGEEEYGFYSTLGKSFRSWFFSRSLDESTLRKQIERVRPLKNTEVWASSTVTVQPSRHSSLDFDHQEPFSTKGQSLDEEVFVESSSGKHLEWLRAPGTLKHLNGDHQGEMRRNGGGNFLDSTNTGVNCVDAGNIEDDNPSASKILRRISAVDSTDFNPDDTMSVEDPQTDVLDSTAFMRYYHVFREGELCSLLKENVSELRILSSGNDHGNWCIIAEKKRGCD
Protein: Forkhead box protein fkh-4 (O17617)
Organism: Caenorhabditis elegans
Function: Transcription factor (By similarity). Regulates expression of a class of small RNAs, known as 21U-RNAs, perhaps acting redundantly with fkh-3 and fkh-5.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089, ECO:0000269|PubMed:12568714}.
Interaction partners:
- Coiled-coil domain-containing protein 69
- Uncharacterized protein
- Forkhead box protein fkh-3
- Zinc finger PHD-type domain-containing protein
- Very Early Transcript
- Nuclear hormone receptor family member nhr-2
- Fork-head domain-containing protein
- Fork-head domain-containing protein
- Putative T-box protein 39
- Putative T-box protein 40
Sequence:
MQSNDENIYFPANQYVNAGQYSPLQQSFSQNSQYDLFDGFAEFGFLEQVPATNMYSGSQSTQMEQNYLPNVNNSTRKRKAPGQNEQATVKRRQIGIEKWRLPSRSVVQPSADISDLRRPPISYVALCALACRNAPDMKITPAGVYAFVLHHWRYYRYANENWKNSVRHQLSSKEHFDEETFQPDPSNPTVRRKFYIVKNPNMIRQNLISDADFDFFRKDSRGIEFYQKMFAGQIGLPRSLFYQIIGNGIPFLAGPENSSMFYQLLGMGKVVGYLETRYFREHYRSEHAATEPKYEEDYANFTEKIPSNAENLMSYGAATERNFQKFDFTDEEIELFHLNISSYHSVQKTCKECNLPNWCTPSVGDVETYVFGRQVPMPVNTPVILQQFETVAEQEGIRNNPLEERKTTEDPRDISILEALA
Protein: Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (Q3UZ09)
Organism: Mus musculus (Mouse)
Function: Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
Subcellular location: Secreted.
Interaction partners:
- Complement C1s-1 subcomponent
- Complement C1s-1 subcomponent
Sequence:
MSGFRGLVPELENSLWSSPTTSCMSKMCWWLLWGILHTCPTQASVLLAQQSPQQLTSPGYPEPYLKGQESHTDIEAPEGFAVRLTFQDFDLEPSPDCEGDSVTISTGGTDATRLCGRQGSPLGNPPGHREFVSSGRSLRLTFQAHSSSKSKITHLHKGFLALYQAVAVNQPNGDTEAVTTPGAPKIQNHCQDPYYKADQTGTLSCPSSWKWKDRQDGGEVPECVPVCGRPVVPLAENPNTFGSSRAKLGNFPWQAFTSIYGRGGGALLGDRWILTAAHTIYPKDSIYLRRNQNVEVFLGHTDIDELLKLGNHPVRRVVVHPDYRQHESHNFNGDIALLELEQRVPLGPNLLPVCLPDNETLYHSGLWGYVSGFGVEMGWLTTKLKYSKLPVAPREACEAWLHQRQRTEVFSDNMFCVGEEMQVNSVCQGDSGSVYVVWDDLALRWVATGIVSWGIGCGKGYGFYTKVLSYMDWIKRVIEGKD
Protein: Secreted frizzled-related protein 3 (Frizzled-related protein 1) (FrzB-1) (D9ZGF6)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MVCGSPGGMLLLRAGLLALAALCLLRVPGARAAACEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVYDRGVCISPEAIVTADGADFPMDSSNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKEIKTKCHDVTAVVEVKEILKSSLVNIPRDTVNLYTSSGCLCPPLNVNEEYIIMGYEDEERSRLLLVEGSIAEKWKDRLGKKVKRWDMKLRHLGLSKSDSSNSDSTQSQKSGRNSNPRQARN
Protein: Calcium-dependent protein kinase 17 (EC 2.7.11.1) (Q9FMP5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- AT5g46770/MZA15_19
- Calcium-binding protein CP1
Sequence:
MGNCCSHGRDSADNGDALENGASASNAANSTGPTAEASVPQSKHAPPSPPPATKQGPIGPVLGRPMEDVKASYSLGKELGRGQFGVTHLCTQKATGHQFACKTIAKRKLVNKEDIEDVRREVQIMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLLRTIVQIVHTCHSMGVIHRDLKPENFLLLNKDENSPLKATDFGLSVFYKPGEVFKDIVGSAYYIAPEVLKRKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAKDLVKKMLNSDPKQRLTAAQVLNHPWIKEDGEAPDVPLDNAVMSRLKQFKAMNNFKKVALRVIAGCLSEEEIMGLKEMFKGMDTDSSGTITLEELRQGLAKQGTRLSEYEVQQLMEAADADGNGTIDYGEFIAATMHINRLDREEHLYSAFQHFDKDNSGYITMEELEQALREFGMNDGRDIKEIISEVDGDNDGRINYDEFVAMMRKGNPDPIPKKRRELSFK
Protein: Synapse differentiation-inducing gene protein 1 (SynDIG1) (Dispanin subfamily C member 2) (DSPC2) (Transmembrane protein 90B) (Q9H7V2)
Organism: Homo sapiens (Human)
Function: May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.
Subcellular location: Cell membrane; Single-pass type II membrane protein. Early endosome membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Postsynaptic density membrane {ECO:0000250}. Synapse {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Note=Shuttles between the cell surface and early endosome membrane. {ECO:0000250}.
Interaction partners:
- Glutamate receptor 1
- Glutamate receptor 2
- Protein cornichon homolog 2
- Protein shisa-9
Sequence:
MDGIIEQKSMLVHSKISDAGKRNGLINTRNLMAESRDGLVSVYPAPQYQSHRVGASTVPASLDSSRSEPMQQLLDPNTLQQSVESRYRPNIILYSEGVLRSWGDGVAADCCETTFIEDRSPTKDSLEYPDGKFIDLSADDIKIHTLSYDVEEEEEFQELESDYSSDTESEDNFLMMPPRDHLGLSVFSMLCCFWPLGIAAFYLSHETNKAVAKGDLHQASTSSRRALFLAVLSITIGTGVYVGVAVALIAYLSKNNHL
Protein: D-aspartate oxidase 1 (DASOX 1) (DASPO 1) (DDO-1) (EC 1.4.3.1) (O45307)
Organism: Caenorhabditis elegans
Function: Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate. Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA. May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells.
Subcellular location: Peroxisome matrix {ECO:0000250|UniProtKB:Q922Z0}.
Interaction partners:
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase
- Aspartate aminotransferase
- D-aspartate oxidase 3
- D-aspartate oxidase 2
- Probable citrate synthase, mitochondrial
- Isocitrate dehydrogenase subunit
- Pyruvate carboxylase 1
- Isocitrate dehydrogenase
- Isocitrate dehydrogenase
Sequence:
MTPKIAIIGEGVIGCSTALQVAQAVPDARVTVLSDRPFEQTCSFGPAGLFRIDDIANREFGKSTFDWFAHLHRTEKGDKTGVKLLSGHIQSDSKERLEQQQKAYGDIVYNFRFLEKREILDLFPNPSEHCIHYTAFASEGNKYVPYLKFQCQARGVEFLHRKVRDLEELANEGYDVIVNCAGLSGGTLAGDDDSVYPIRGVVLDVEAHWHKHFNYKDFITFTIPKENSVVIGSVKQENRWDLEITDVDRKDILERYVALHPAMREPKILGEWSGLRPARKTIRIEKVEKKSEKSGKKYTVVHHYGHGGNGFTLGWGTAVEATKLVKSALNSSKL
Protein: Nucleolar protein 16 (D6RIC3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MPKAKGKTRRQKFGYSVNRKRLNRNARRKAAPRIECSHIRHAWDHAKSVRQNLAEMGLAVDPNRAVPLRKRKVKAMEVDIEERPKELVRKPYVLNDLEAEASLPEKKGNTLSRDLIDYVRYMVENHGEDYKVSGSGPVGWLGRRPGPFAA
Protein: Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) [Includes: Alkaline phosphodiesterase 1 (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] (P39997)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mediates extracellular nucleotide derived phosphate hydrolysis along with NPP1 and PHO5.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Outer spore wall protein 7
- Ectonucleotide pyrophosphatase/phosphodiesterase 1
- Outer spore wall assembly protein SHE10
- Outer spore wall protein 6
- Uncharacterized protein YEL014C
- SCOCO-like protein 1
- Outer spore wall protein 4
- Outer spore wall protein 2
Sequence:
MLLFEQPVDLEKNNEDDTNIKPFAISRHFLLKLLLCGIILIELLLYSKCPKPIDNGPRTIANRSNTYFNGTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSNTADPIWQLLQTESQGEYKVATHMWPGSEVVYEDHGDVPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIPNVDSYGHSFGYDLRDKRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGDEISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGDIWILADEYYAIVKEMGDVPIGIMGTHGYNFNNCSDMASIFIGMGPMFNNEVVPPFENIEVYNMLIKASALLGEEKTKKEKSLLQ
Protein: NGG1-interacting factor 3 (P53081)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823961}.
Interaction partners:
Sequence:
MSRAITRAQLDKLVRSITKFYPQKYADKSWDNTGLLIDCSTAQVTTADANAKTKVLLTVDLTKSVAQEAVDANCNVIVAYHPFIFPSWNRLSPHTNPQHETAIKLIQYGISVYCPHTAVDAARGGVNDWLVRGLNNGENVAKSYALETVSGETDDLIGYGRFVEFNKDISLEQIVKNVKRVLRVPYVQVASLAAPSAWNQLKIKKVAVCAGSGSGVFKQLKEDVDLYYTGEMSHHEVLKWKEMGKTVIVCNHSNTERGFLQDVMKGLLQDEGHEVVVSKMDCDPLTVA
Protein: F21J9.27 (Rubisco methyltransferase family protein) (Q9FYK3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Hydroxyproline-rich glycoprotein family protein
- ETFB lysine methyltransferase
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Chaperonin 60 subunit beta
- Protein arginine N-methyltransferase 1.6
- Calmodulin-lysine N-methyltransferase
Sequence:
MANSKMAIASLAAQIRPFTCLAASLPSRLAPHPPDLIRWIKREGGFVHHAVKLSQETQFGIGLISTEQISPGTDLISLPPHVPLRFESDDSSSSSSSLLSALARRVPEELWAMKLGLRLLQERANADSFWWPYISNLPETYTVPIFFPGEDIKNLQYAPLLHQVNKRCRFLLEFEQEIRRTLEDVKASDHPFSGQDVNASALGWTMSAVSTRAFRLHGNKKLQGGSSDDVPMMLPLIDMCNHSFKPNARIIQEQNGADSNTLVKVVAETEVKENDPLLLNYGCLSNDFFLLDYGFVIESNPYDTIELKYDEQLMDAASMAAGVSSPKFSSPAPWQHQLLSQLNLAGEMPNLKVTIGGPEPVEGRLLAALRILLCGELVEVEKHDSDTLKSLSAVAPFGIANEIAVFRTVIALCVIALSHFPTKIMEDEAIIKQGVSATAELSIKYRIQKKSVIIDVMKDLTRRVKLLSSKETPTAA
Protein: General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein) (Q9JJA9)
Organism: Mus musculus (Mouse)
Function: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8R4T5}. Cell membrane {ECO:0000250|UniProtKB:Q8R4T5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8R4T5}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8R4T5}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q8R4T5}.
Interaction partners:
- Cytohesin-2
- NT-3 growth factor receptor
- Neurochondrin
- FERM and PDZ domain-containing protein 4
- Cytohesin-3
- Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
- Disks large homolog 4
Sequence:
MTLRRLRKLQQKEEATAAPDPAGRAPDSEAARAAPLPSGPPAAAAPPGAPGEELYAALEDYHPAELYRALAVSGGTLPRRKGSGFRWKNFTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAAPGSARGGARRAKGDTDDAVYHTCFFGGAEPQALPPPPPPARALGPSSAETPASVLFPAPRSTLSRSASVRCAGPGGGGGAPGALWTEAREQALCGAGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL
Protein: Veneno (Q9VHR5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RE73736p
Sequence:
MLAQKSVAGADELAQAKGKCVHCANAAERVCQRCGDFYCSKHCQRQDWLRHRYICIPLPALVSPNEYSVFQSDRESTLEGACSLNADKSVVEASPIPLSRSPILPDLQCNNAGRSSIIAAKDDIPVSPPKAIIPPSGAMVYITDFISSNRCYIRDASESAERAFDEVCKKVNTIATLLPRIKNPPPNRLCLVHFNGMYVRAKMCKKLREVSHLFLVDLGIKHSGPFFDFKDINDELKALPCSSQLVQLKNVLNCDYSNDVIAFNSKFVGKKYMATIKKCPGLHLVELVNTEMNFSVNEQLNAFFNSKKLLRNPNSAAENIKSCSLEGPQPSHIDQPIAIPAIECKKMLTKPEVQNECEEILKQQNSGQIDQSKSTNVLVTEGASNKMLGFIDLADKATKTDQDTAPKPKDEDVKHSLTQCLTPKANYPLQLPNHKKNLELPVIHKTNAQTNGIVMSKNEHVLKPPFEMRRFSIESKEGIDLIVVDSTKKNRGIFGAFDSTYASEFSALHSRLSEITDCEPYKPVVREYVLARFEGSWYRGKVEQIIVVPRQQTKYRVMYLDYTNVEDITEMDIRRYPLDFTAPCATNLCVIDEFPHNPNAAQVSYLAEVLKVHQSVHIDSIKYINHIAVIKSGSLIQKLLSL