wanglab/gogpt-training-data huggingface dataset:
Protein: RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein) (O08856)
Organism: Mus musculus (Mouse)
Function: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (By similarity). Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P55199}. Nucleus speckle {ECO:0000250|UniProtKB:P55199}. Nucleus, Cajal body {ECO:0000250|UniProtKB:P55199}. Note=Colocalizes with EAF2 to nuclear speckles. Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes (By similarity). {ECO:0000250|UniProtKB:P55199}.
Interaction partners:
- AF4/FMR2 family member 1
- Protein AF-9
- AF4/FMR2 family member 4
- Btk-PH-domain binding protein translocated to, 1)
- ELL-associated factor 1
- Cyclin-T1
- Cyclin-dependent kinase 9
- ELL-associated factor 2
- Cyclin-T2
- Mediator of RNA polymerase II transcription subunit 26
Sequence:
MAALKEARSYGLSCGRVSDGSRVSVFHVKLTDSALKAFESYRAHQDSVSLRPSIRFEGSQGHISIPQPDCPEEVRAFSFYLSNIGRDSPQGSFDCIQQYVSSYGDVHLDCLGSIQDKVTVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYMGKKVQFRKPAPGAADAVPSRKRATPINLASAIRKSSGSGASSVVQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDTLDSLLQQVASVNPKDGTCTLQDCMYKSLQKDWPGYSEGDRQLLKRMLMRKLCQPQNATTDSSPPREHGRSASPSQKRPTDFIDPLASKKPRISHFTQRAQPTLNGKLGAPNGHETLLPAPGPTPSDTLSSSHLPPRLEPPRTHDPLADVSNDLGHSTQDYKHQEATPAPAPHLGLPLLTDFPQAEQPTSSSHTHSRPKKKSKKHKDKERPPEERPPAPQPDAPTAPALPPDAPGLNGACDNEPTSSSETPDYLLKYPAISSSEQRQSYKNDFNAEYSEYRSLHARIEQITRRFTQLDAQLRQLSQGSDEYETTRGQILQEYRKIKKTNTNYSCEKRRCEYLHRKLAHIKRLIAEYDQRQLQAWP
Protein: Zinc finger protein 140 (P52738)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation as a repressor.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MSQGSVTFRDVAIDFSQEEWKWLQPAQRDLYRCVMLENYGHLVSLGLSISKPDVVSLLEQGKEPWLGKREVKRDLFSVSESSGEIKDFSPKNVIYDDSSQYLIMERILSQGPVYSSFKGGWKCKDHTEMLQENQGCIRKVTVSHQEALAQHMNISTVERPYGCHECGKTFGRRFSLVLHQRTHTGEKPYACKECGKTFSQISNLVKHQMIHTGKKPHECKDCNKTFSYLSFLIEHQRTHTGEKPYECTECGKAFSRASNLTRHQRIHIGKKQYICRKCGKAFSSGSELIRHQITHTGEKPYECIECGKAFRRFSHLTRHQSIHTTKTPYECNECRKAFRCHSFLIKHQRIHAGEKLYECDECGKVFTWHASLIQHTKSHTGEKPYACAECDKAFSRSFSLILHQRTHTGEKPYVCKVCNKSFSWSSNLAKHQRTHTLDNPYEYENSFNYHSFLTEHQ
Protein: Transcription factor EB (G5CIM3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSSRIGLRLQLMRDQMQQEEQRERQQQQAVSMHYMQHRMPGPPEPTPAISAPTHFQGPMQVPVEVLKVQTHLENPTDYHIRQSQRQQVKEYLSTTYATKQAVHAVTSLVQPSPPPMVQAQTGSAPPNMHSPCMRTEQLMNSAGNSAPNSPMAMLNISSSHENEMDDLIDNIISLQSSYDDIQAYNDPVVQMPNTLPLSSSHLDVYTGPGMSGSAIAMTSNSCPANLAIKRELSDVEARAMAKERQKKDNHNLIERRRRFNINDRIKELGTMIPKTNDLDVRWNKGTILRASVDYIKRMQKDVQRTREVENNFRRMEMANKQLWLRIQELERQAQIHGLPSNSPSGLTNTDHQNPFIKQESSPEENHLQHQSHLPPRYPQQHPQPHPQLHQHQHLHPQPPLQYPAVGSSQHFDLAQSLDLCDGGIPGYQDGLGDLGFLGGGIAQMGKKSELSFLLMEEALSPLGGDPLLSAMSPEASVDSSRRSSFSIEDSDIQ
Protein: THO complex subunit 2 (Tho2) (B1AZI6)
Organism: Mus musculus (Mouse)
Function: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. Plays a role for proper neuronal development.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8NI27}. Nucleus speckle {ECO:0000250|UniProtKB:Q8NI27}. Cytoplasm {ECO:0000250|UniProtKB:Q8NI27}.
Interaction partners:
- THO complex subunit 6 homolog
- THO complex subunit 7 homolog
- THO complex subunit 3
- THO complex subunit 1
- THO complex subunit 5 homolog
- Spliceosome RNA helicase Ddx39b
- THO complex subunit 4
- Aly/REF export factor 2
- AKT-interacting protein
- TGFB-induced factor homeobox 2-like, X-linked 1
Sequence:
MAAAAVVVPAEWIKNWEKSGRGEFLHLCRILSENKSHDSSTYRDFQQALYELSYHVIKGNLKHEQASSVLNDISEFREDMPSILADVFCILDIETNCLEEKSKRDYFTQLVLACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAELGQDLSGNITSDLILENIKSLIGCFNLDPNRVLDVILEVFECRPEHDDFFISLLESYMSMCEPQTLCHILGFKFKFYQEPSGETPSSLYRVAAVLLQFNLIDLDDLYVHLLPADNCIMDEYKREIVEAKQIVRKLTMVVLSSEKLDERDKEKDKDDEKVEKPPDNQKLGLLEALLKVGDWQHAQNIMDQMPPYYAASHKLIALAICKLIHITVEPLYRRVGVPKGAKGSPVSALQNKRAPKQVESFEDLRRDVFNMFCYLGPHLSHDPILFAKVVRIGKSFMKEFQSDGSKQEDKEKTEVILSCLLSITDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNGHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTTISSWLQSLASFCGAVFRKYPIDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQEGGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQHKVHKYITSCEMVMAPVHEAVVSLHVSKVWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKSTKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRATGFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVNKICQEEKEKRPDLYALAMGYSGQLKSRKSHMIPENEFHHKDPPPRNAVASVQNGPGGGTSSSSIGNASKSDESGAEETDKSRERSQCGTKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKVKEKEKEKKEKTPATTPEARALGKDSKEKPKEERPNKEDKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPIVESKSTQEREREKEPSRERDVAKEMKSKENVKGGEKTPVSGSLKSPVPRSDISEPDREQKRRKIDSHPSPSHSSTVKDSLIDLKDSSAKLYINHNPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDITKRRKEENGTMGVSKHKSESPCESQYPNEKDKEKNKSKSSGKEKSSSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKSSDKHR
Protein: Jade family PHD finger 2 (A0A0C4DFT8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSSTMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSFCQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRAGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
Protein: NAC domain-containing protein 16 (ANAC016) (Protein NTM1-like 3) (A4FVP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). Transcriptional activator that promotes leaf senescence by up-regulating senescence-associated genes in response to developmental and stress-induced senescence signals. Functions in salt and oxidative stress-responsive signaling pathways. Binds to the promoter of NAC029/NAP and NAC059/ORS1 genes.
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q949N0}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000250|UniProtKB:Q949N0, ECO:0000255|PROSITE-ProRule:PRU00353}. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon specific stress or signal, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP). {ECO:0000250|UniProtKB:Q949N0}.
Interaction partners:
- Magnesium dechelatase SGR1, chloroplastic
- ABSCISIC ACID-INSENSITIVE 5-like protein 5
Sequence:
MVDSSRDSCFKAGKFSAPGFRFHPTDEELVVYYLKRKICCKKLRVNAIGVVDVYKVDPSELPGLSMLKTGDRQWFFFTPRNRKYPNAARSSRGTATGYWKATGKDRVIEYNSRSVGLKKTLVFYRGRAPNGERTDWVMHEYTMDEEELGRCKNAKEYYALYKLYKKSGAGPKNGEQYGAPFQEEEWVDSDSEDADSVAVPDYPVVRYENGPCVDDTKFCNPVKLQLEDIEKLLNEIPDAPGVNQRQFDEFVGVPQGNSAEVIQSTLLNNSSGEYIDPRTNGMFLPNGQLYNRDSSFQSHLNSFEATSGMAPLLDNEKEEYIEMNDLLIPELGASSTEKSTEFLNHGEFGDVNEYDQLFNDISVFQGTSTDLSCLSNFTNNTSGQRQQLLYEQFQYQTPENQLNNYMHPSTTLNQFTDNMWFKDDQAALYVQPPQSSSGAFTSQSTGVMPESMNPTMSVNPQYKEGQNGGGTRSQFSSALWELLESIPSTPASACEGPLNQTFVRMSSFSRIRFNGTSVTSRKVTVAKKRISNRGFLLLSIMGALCAIFWVFKATVGVMGRPLLS
Protein: DnaJ homolog subfamily C member 24 (CSL-type zinc finger-containing protein 3) (Diphthamide biosynthesis protein 4) (Q6P3W2)
Organism: Homo sapiens (Human)
Function: Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Elongation factor 2
- Elongator complex protein 4
- Mitochondrial inner membrane protease subunit 1
- Doublecortin domain-containing protein 1
- 2-
- Diphthamide biosynthesis protein 3
- Metallophosphoesterase MPPED2
- 2-
- Diphthine methyl ester synthase
- Diphthine methyltransferase
Sequence:
MMAVEQMPKKDWYSILGADPSANISDLKQKYQKLILMYHPDKQSTDVPAGTVEECVQKFIEIDQAWKILGNEETKREYDLQRCEDDLRNVGPVDAQVYLEEMSWNEGDHSFYLSCRCGGKYSVSKDEAEEVSLISCDTCSLIIELLHYN
Protein: Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPATase) (P0AG16)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. Can also use NH(3) in place of glutamine.
Interaction partners:
- Phosphoribosylformylglycinamidine synthase
- Phosphoribosylamine--glycine ligase
- Bifunctional purine biosynthesis protein PurH
- Phosphoribosylformylglycinamidine cyclo-ligase
- Phosphoribosylglycinamide formyltransferase
- Colicin V production protein
- N5-carboxyaminoimidazole ribonucleotide synthase
- N5-carboxyaminoimidazole ribonucleotide mutase
- Adenylosuccinate lyase
- Carbamoyl phosphate synthase large chain
Sequence:
MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHNGNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAENPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG
Protein: Membrane-spanning 4-domains subfamily A member 6A (CD20 antigen-like 3) (Four-span transmembrane protein 3) (Q9H2W1)
Organism: Homo sapiens (Human)
Function: May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Putative membrane-spanning 4-domains subfamily A member 4E
- Scavenger receptor cysteine-rich type 1 protein M130
- Membrane-spanning 4-domains subfamily A member 10
- Phospholipid-transporting ATPase ABCA7
- Membrane-spanning 4-domains subfamily A member 7
- TYRO protein tyrosine kinase-binding protein
- Phosphatidylinositol-binding clathrin assembly protein
- CD2-associated protein
- Myeloid cell surface antigen CD33
- Myc box-dependent-interacting protein 1
Sequence:
MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDCGYEELLTS
Protein: 26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55) (Q9D8W5)
Organism: Mus musculus (Mouse)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 1
- Proteasome subunit alpha type-2
- 26S proteasome regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome regulatory subunit 6A
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 4
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 11
Sequence:
MADGGSERADGRIVKMEVDYSATVDQRLPECEKLAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTENLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESDKWQQALKSVVLYVILAPFDNEQSDLVHRISSDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGVELRKGSSETPATDVFSSTEEGEKRWKDLKSRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGVINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
Protein: Zinc-finger homeodomain protein 8 (AtZHD8) (Homeobox protein 30) (AtHB-30) (Zinc finger homeodomain transcriptional factor ZFHD3) (Q9LXG0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription factor.
Subcellular location: Nucleus {ECO:0000250}. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm. {ECO:0000250}.
Interaction partners:
- At3g49930
- Zinc finger protein 7
- Transmembrane E3 ubiquitin-protein ligase FLY1
Sequence:
MDVIATTTTIVSDLDSRQPEIEAPIRIQPAKPISFSNGKRCHHHHLASEAVAVATYKECLKNHAAGIGGHALDGCGEFMPSPSFNSNDPASLTCAACGCHRNFHRREEDPSSLSAIVPAIEFRPHNRHQLPPPPPPHLAGIRSPDDDDSASPPPISSSYMLLALSGGRGGANTAVPMSRKRFRTKFSQYQKEKMFEFSERVGWRMPKADDVVVKEFCREIGVDKSVFKVWMHNNKISGRSGARRANGGVVVGGVGDSRQSVVPTNGSFSST
Protein: Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22) (A0A0G2K5L2)
Organism: Rattus norvegicus (Rat)
Function: Mitochondrial glutamate/H(+) symporter (By similarity). Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (Probable). Plays a role in the control of glucose-stimulated insulin secretion.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:19584051}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKMLAAQAQLATQGGGQPSVEAPAAPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQEPQA
Protein: Ah1644 protein (Formin 3, isoform A) (Q86C16)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDSRIGLDYIVENRDYIAKLGAALDTQNATVKKQVFELLSALCAYSPDGYARAIETLEFYKNLKKQRYRFKIVINELELSSAAAHPPLDYQAALLAFINCVIISAATLQERIRIRNEFIGLKVLPLLNNLRKVAQSVGDIIVQLDVFVEQQECDEAQSLQAPDGINLNSHLDVFYAILRQVADTPQEVPFLNILQHLLRIDPKEPLSDIIWDTTERLVHRATLLESHEDSVRLLRTPSSQKFACQSCRGSDASSPTRKPSQPVGVSAKTTPPPPPPPMAPAAPPPPPPPINGAAPPPPPPPMINGGALPPPPPPPSMQMASRPRTPDPLAAEAVATAILLPQQDTPAPKAKMKTINWGKIPHNKVLGKQNIWSIVASNHQDSPMQDIDWNEMEGLFCLQTASAQGSPKLGRDGSQAAAGSNGCDTLDRKSKKESTEITLLDGKRSLNVNIFLKQFRTSNDDIIQLIRQGAHEEIGAERLRGLLKIMPEVDELDMLKGFNGDKARLGNAEKFLLQLLEVPNYKLRIESMLLKEEFAANVAYLEPCINSMLYAGDDLLNNKTLQEVLYMVVVAGNFLNSGGYAGNAAGVKLSSLQKLTDIRANKPGMNLIHFVALQAEKRNPELLQFTGQLSNLESASKTTSEQINNEINTLDGRIRRIARQIEQPATDVDIKEQMADFLQAAESELSVLQAGMKQVESMRLKMSEFFCDDAATFRLEECFKIFHNFCDKFKQAVKENERRQQQEQQATLRRKQREEQLARRARQIGQAGTPVSDSEHSFLGDAIFDPRASPALSRRHLGSGEISNGFIRLEQDGASPDITPNGSLRRRRSRVLAEEDDLMEFLRSSTGPHHDGHNSRERKAAYGSLDRSWARRARSGSSSRKRPDLLNIDFGMDRERASSPAPLLQQQQQNVQERLQSPLASTAGTPTTAANTPTGSGSAIAQTPSNNEDAKPRISREWRQKIETWLQSNESDEKQNEEYRRKRRLVNANRRSLENETENERKLDPLPEEKILPSTTTATPTNTPTTTNPTNSTNRMDQESGKYQRVYADWKPSRTLEQTDVVANLQAIADAQPHDALRQHRRQRSQEQPSPIALQSIAEEDRRKSLIQKQGERDKSNERLQIYIRRSSSRELQPAKTEEHPLPPKSPKPQVSDDTFASLLSHHKTQNEMQGSSKDVDADNIETPPVSRRVIATPTTTVVTVSMTDKPKAATEEKINPAEQDAPGHFDRHALARRTRRYKRPTDYSSGNEEALTTSTAEAKTSPSKPEPPAPEKSKQKERTINKLEKVGRHISSINQEDVREAIRNLKSPTGTPERPWSPPRDITPSKLKLSASGHHELNDEGFEETQSLVSDTPSHGKGESTNSSCNEGVNETPARQRPMQKQKPTTTSISQMGSRLADRLQQARMKSSGSSGSAASKSQNQIPATQTATVKRSLSASRPLRMPNGQPLASAAPLRSASTVRRSPQEQQVLAGVERSSSRNSLRSSRSSINSGASTQTVVRRLPAVQRAGATVSVDSSPSKRPLAAQNLRPTQGRGVPASRSSSSGSSVGPSVILVRSKMSNTAPKSSIHGSTSFKENQSQSQPQSQSRMSAARSVVLVKNALNQQQQARMSANPSPQQRSTSSSRSVSSFMRPTASSATKRQK
Protein: Enriched in surface-labeled proteome protein 18 (Q38B92)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGRRHGVIRGFIFVLFLLLCATAAANVSREEQSHAREGGGAQATAEPSFSLLSVCKQEAHKLCPRQEHAPLKCLLHHFASSRSGPGINEARNLASANPLRRSYRNTAFFNRECAAWLRAREECVSFVRRAGYCRDDETARECLRRIPQHVLRPSCRNSAYYNSVLLYGKMKQQQQQESVSQDSSA
Protein: Canavalin (P50477)
Organism: Canavalia ensiformis (Jack bean) (Dolichos ensiformis)
Function: Seed storage protein.
Interaction partners:
Sequence:
MAFSARFPLWLLLGVVLLASVSASFAHSGHSGGEAEDESEESRAQNNPYLFRSNKFLTLFKNQHGSLRLLQRFNEDTEKLENLRDYRVLEYCSKPNTLLLPHHSDSDLLVLVLEGQAILVLVNPDGRDTYKLDQGDAIKIQAGTPFYLINPDNNQNLRILKFAITFRRPGTVEDFFLSSTKRLPSYLSAFSKNFLEASYDSPYDEIEQTLLQEEQEGVIVKMPKDQIQEISKHAQSSSRKTLSSQDKPFNLRSRDPIYSNNYGKLYEITPEKNSQLRDLDILLNCLQMNEGALFVPHYNSRATVILVANEGRAEVELVGLEQQQQQGLESMQLRRYAATLSEGDIIVIPSSFPVALKAASDLNMVGIGVNAENNERNFLAGHKENVIRQIPRQVSDLTFPGSGEEVEELLENQKESYFVDGQPRHIDAGGKARRAHLPNLFRTFY
Protein: Aureochrome 1 (V5RGX6)
Organism: Nannochloropsis gaditana
Interaction partners:
Sequence:
MAAIQQPTSWGILSRNNSSTDLAGEAGGLEAPDQIKQEAAAPLWTAPLYASANNSNPMADTVDLDEIFADDFLLPGMGMVPFGTEGDMGPEDMFPGGLSCDTSVATNDNDDSAVASGMHGKGKGAQFANAAPQGETEDKTNVRAAAVVRSAASRTRSGITTRLGLNKGQGRAVTGASSMLPSAVPSRARVPTRKGSLPVEEEEDVEEEEEEYETGSEEEGEGGDGRGARRRKKAKLTLKPLTEAQRVERRERNREHAKRSRMRKKFMLESLQAQMLALRKENLRLRQLVATKLPDKADTILRGCSSIKTQNLLSSVELGHHRALADHDGRLVSALQFAQQNFTVSDPSLPDNPIIYASQGFLDLTGYTSDQIVGRNCRFLQGPGTDPAAVDIIRRGVALGEDTSVCLLNYRADGTPFWNQFFVAALRDMEGNIVNYVGVQCKVEEAPMEEELKERVKTINFDEEE
Protein: Low Calcium Response Protein H (Putative type III secretion low calcium response chaperone LcrH/SycD) (Type III secretion chaperone) (Q9Z6N8)
Organism: Chlamydia pneumoniae (Chlamydophila pneumoniae)
Interaction partners:
- Type III secretion translocator
- Low calcium response E
- Secretion protein
- Adenylate cyclase-like protein
- Uncharacterized protein
- Low Calcium Response Protein H
- Uncharacterized protein
- Omp
- Protein CPn_1016/CP_0837/CPj1016/CpB1054
- VIT family protein
Sequence:
MSHLNYLLEKIAASSKEDFPFPDDLESYLEGYVPDKNIALDTYQKIFKISSEDLEKVYKEGYHAYLDKDYAKSITVFRWLVFFNPFVSKFWFSLGASLHMSEQYSQALHAYGVTAVLRDKDPYPHYYAYICYTLTNEHEEAEKALEMAWVRAQHKPLYNELKEEILDIRKHK
Protein: Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1) (P37230)
Organism: Rattus norvegicus (Rat)
Function: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2 (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Retinoic acid receptor RXR-alpha
- Period circadian protein homolog 2
- Nuclear receptor coactivator
- Nuclear receptor corepressor 2
- Retinoic acid receptor RXR-beta
- phosphatidate phosphatase
- Nuclear receptor corepressor 1
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
Sequence:
MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSLGEESSGSFSFADYQYLGSCPGSEGSVITDTLSPASSPSSVSCPAVPTSTDESPGNALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLAYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDLKDSETADLKSLAKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFVIHDMETLCMAEKTLVAKMVANGVENKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKLQEGIVHVLKLHLQSNHPDDTFLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY
Protein: Meiotically up-regulated gene 136 protein (O43061)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. Golgi apparatus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Alpha-1,2-galactosyltransferase gmh3
- Probable alpha-1,2-galactosyltransferase gmh1
- Uncharacterized alpha-1,2-galactosyltransferase C1289.13c
- Probable alpha-1,2-galactosyltransferase gmh2
- Alpha-1,2-galactosyltransferase
Sequence:
MRLYFSAFRHPKRLGLCLLITLSIILLGWQCVLLYNHSPEIQRSVYTLTGLAPSSKMAFVTMLTVRAANGENEVENTQQDWYYNSTRLLVHRLVKFKPTKSKYPVVVLAMKGIDQWKLDQLQEDGAIVKVVDPLYAHEVVDDVNDIALLDSRWSMMFTKLRVFEMYEYDRICFLDSDILPIKKMDKVFDVHQLSYSKDSVLFPPTLFYKPRRSIFWRRFTEEFAAYGLTRDDLYPYVFAAVSDPGMWHETPPPFKDYFNAGLFVFKPLKAHYKRLMALARFPKLYDNANMMEQSLLNFAYNSAGAFPWESLDWTFNGLWARKNDLPYLKAVHGKHWQPEGSLGYDEDTSKLWWDAFQEMQTYHDQQRNADLY
Protein: Putative serine protease F56F10.1 (EC 3.4.-.-) (P90893)
Organism: Caenorhabditis elegans
Interaction partners:
- EGF-like domain-containing protein
- DUF19 domain-containing protein
- Putative phospholipase B-like 2
- Carboxypeptidase
- Pept_C1 domain-containing protein
- Galectin
- EGF-like domain-containing protein
- Carboxypeptidase
- C-type lectin domain-containing protein
- Serine carboxypeptidase ctsa-4.1
Sequence:
MLRNLLLLLLPLLIEAKLPPFFLGRLNGKTLLNHHLDRLTASDGASIQETYPNLQVHNFTQKLDHFDPYNTKTWNQKYFYNPVFSRNNSIIFLMIGGEGPENGKWAANPNVQYLQWAKEFGADVFDLEHRFFGDSWPIPDMQTSSLRYLTTQQALADLAFFIEFMNQQYGFKNPRWVTFGGSYPGSLAAWFRQKYPQLTVGSVASSAPVNLKLDFYEYAMVVEDDLRITDPKCAQATKDAFVQMQKLALTAEGRNSLNNHFNLQPPFDANTTKLDINNFFGNIFNTYQGMTQYTYDGQSNSTHSDKTVRKMCDIMTNATETDVVMRVENLFLWFNQMEPASANLTVMPNSYWDVISQVGSGDLNVLGPDGAAARGWMWLCCNEIGFLQTTNQGNNVFGTGVPLNLFIDMCTDMFGDSMKMSQIMGGNKKSQNYYGGADFYNATNVVLPNGSLDPWHALGTYGTIKSQSLLPYLINGTAHCGDMYPSYDGEPGSLLAARAFVKENVRQFIRYDPNVDGPGGSSSSASLFVVAYIVCGFLFV
Protein: Signiferin-2.2 (P86132)
Organism: Crinia signifera (Common eastern froglet)
Function: Has antibacterial activity against a wide spectrum of Gram-positive bacteria including B.cereus, E.faecalis, L.lactis, L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis. Lacks antibacterial activity against the Gram-negative bacteria E.cloacae and E.coli.
Subcellular location: Secreted {ECO:0000269|PubMed:15317042}.
Interaction partners:
Sequence:
IIGHLIKTALGFLGL