wanglab/gogpt-training-data huggingface dataset:
Protein: Phototropin-1A (EC 2.7.11.1) (Non-phototropic hypocotyl protein 1A) (OsNPH1a) (Q2QYY8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Protein kinase that acts as a blue light photoreceptor in a signal-transduction pathway for phototropic responses. Regulates a wide range of physiological activities in plants that maximize the efficiency of photosynthesis, such as chloroplast relocations, stomata opening, and leaf expansion (By similarity).
Interaction partners:
- Serine/threonine-protein phosphatase BSL1 homolog
Sequence:
MASKGTEGGHGGVERKEQQQQRGYQLPRDSRGSLEVFNPSSASSFRTAAAAPKSASPFLAIPDREEDNVVAQQRAAEWGLVLQTDHHTGLPQGVSARPSSGSARTSSEDNPQQQQSAAAIPRVSEELRAALSAFQQTFVVSDATHPNHPIMYASAGFFNMTGYTSKEVVGRNCRFLQGSGTDPHEIDKIRQSLANGSNYCGRILNYKKDGTPFWNLLTIAPIKDEDGRLLKFIGMQVEVSKYTEGKKDTVVRPNGLSESLIKYDARQKDHARSSVSELLLALKNPRSLSESSNNTLKRKSQESLSMSMTEVPSKRSSESGSRRNSRSGTRSSLQKINEVPDQGNRTRKSGLRAFMGFLGMGHGSVEKNMLKPRDEDPLIDSDDERPESFEDEFRRKEMRRGIDLATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYNREEILGRNCRFLQGPETDRATVRKIRDAIDNQAEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVQDDAAKEGVVLVKKTADNIDEAAKELPDANLRPEDLWANHSKVVLPNPHMKDTASWRAIQKVLESGESIGLKHFRPVKPLGSGDTGSVHLVELLNTGEYFAMKAMDKSIMLNRNKVHRATAERQILDLLDHPFLPTLYASFQTKTHICLITDYCPGGELFVLLDNQPLKVLHEDAVRFYAAEVVVALEYLHCQGIIYRDLKPENILLHRDGHISLTDFDLSCLTSCRPQVFLPEDADEKKGRKNGSYPIFFAEPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLAARQLMYRLLHRDPANRLGSYEGANEIKGHPFFRGINWPLIRATAPPKLEIPLFSKDDMEKKGLVTNNRTDMF
Protein: Mannosyltransferase (Q59QH4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MISFISLRRRKLISILAIFTIFILSGSIIGYYNGHHHIIKMVENYTPDDFQNSITALTNKFDFSYLPGFKGIITKNNSTSFESLDDLDINGFSLIPGNVQFKFLNKGNKKGTPEQILEQNMKDYKELLGSKTIGQPKDAKLVPPPPPEELPNYKRANATILSLVRNGELGAIGSSIKRLQKKFNSKYNYPYTFLNDEPFTDRFKQRILKYTGNAPVEFVQIKPEYWQKPSFIDTVKEAKEMEIMFKHDVAYAKKQSYHNMCRFYSSQFYKIPELQKYKYYWRVEPKVNFFTDINYDVFKYMEDTQKIYGFTINLYDNEETVKTLWPETIKYLNQGDNYKYINPKGSFQWLLEDLQNPKKTKFAGGYSTCHFWSNFEIGDFDFFRNEAYDNWVKYLDSTGKFYYERWGDAPVHSIGVSLFADKDKIHFFKDIGYDHDPYTNCPNTETTQMCEIGKFSRWEHLYDQNCLMNWLHHDQPKDVY
Protein: Ribulose-phosphate 3-epimerase, chloroplastic (EC 5.1.3.1) (Pentose-5-phosphate 3-epimerase) (PPE) (R5P3E) (RPE) (Q43157)
Organism: Spinacia oleracea (Spinach)
Function: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:9523694}.
Interaction partners:
Sequence:
MSAASLCQSTLQSQINGFCGGLNIRKLQPSTSSPNSLTFTRRKVQTLVKATSRVDKFSKSDIIVSPSILSANFAKLGEQVKAVELAGCDWIHVDVMDGRFVPNITIGPLVVDALRPVTDLPLDVHLMIVEPEQRVPDFIKAGADIVSVHCELASTIHLHRTVNQIKSLGAKAGVVLNPGTPLSTIEYVLDVVDLVLIMSVNPGFGGQSFIESQVKKISDLRKMCVEKGVNPWIEVDGGVTPANAYKVIEAGANALVAGSAVFGAKDYAEAIKGIKASKRPEPVAV
Protein: Transporter (Q86P29)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKDLKTEILVSGGLPKLETSRCAGSGEALLKPSLLPMALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFDFAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCREEWGDGCVSASGGQPLQGQLSRNFSSSTQLYLQRIVLNETDSLEKGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNVKLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTMRPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANFKQPKGSLKSRINNSIKPHSDWGPSDPKKLMDYQMFLRNKDEENSKNVNRRCVCYTAGDRIFG
Protein: CCR4-NOT transcription complex subunit 9 (Cell differentiation protein RQCD1 homolog) (Rcd-1) (Q5PQL2)
Organism: Rattus norvegicus (Rat)
Function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors. May play a role in cell differentiation (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9JKY0}. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q9JKY0}. Note=NANOS2 promotes its localization to P-body. {ECO:0000250|UniProtKB:Q9JKY0}.
Interaction partners:
- CCR4-NOT transcription complex subunit 1
- CCR4-NOT transcription complex subunit 2
- CCR4-NOT transcription complex subunit 3
- CCR4-NOT transcription complex, subunit 7.
- CCR4-NOT transcription complex subunit 4
- CCR4-NOT transcription complex subunit 6
- CCR4-NOT transcription complex subunit 10
- CCR4-NOT transcription complex, subunit 8, isoform CRA_a.
- CCR4-NOT transcription complex subunit 11
- poly
Sequence:
MHSLATAAPVPTALAQVDREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ
Protein: (E,E)-alpha-farnesene synthase (EC 4.2.3.46) ((E)-beta-ocimene synthase) (EC 4.2.3.106) (Terpene synthase TPS-Far/Oci) (PgxeTPS-Far/Oci) (F2XF99)
Organism: Picea engelmannii x Picea glauca (Hybrid white spruce)
Function: Terpene synthase (TPS) involved in the biosynthesis of sesquiterpene and monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens. Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to (3E,6E)-alpha-farnesene and of (2E)-geranyl diphosphate (GPP) to (E)-beta-ocimene.
Interaction partners:
Sequence:
MASVDQSQLCSKSVSMSLSVDDGVQRRTGDYHSNLWDDDFIQSLSTPYGAPCYRERAERLIGEVKEMFNSVRLSPLNDLLQGLSMVDSVERLGIDRHFKNEIKSALDYVYSYWSEKGIGCGRESVVTDLNSSALGFRALRLHGYPVSSDVFKDQNGQFACSANTQTEGEMRGVLNLFRASLVAFPGEKVMEDAERFSAIYLKEALKTVPICSGSLSGEIEYVLEYGWLTNFPRLEARNYIDIFGKDTSPCLQTEKLLELAKLEFNIFHSLQQRELKQVSRWWKDSGFSQLTFTRHRHVEFYTLASCIAIEPKHSAFRLGFAKLCYLGIVLDDIYDTFGTMDELELFTAAIKRWDPSATECLPEYMKGVYMVFYECVNQMAREAEKTQGRDTLSYARNTWEAVFDAFLEEAKWISSGYIPTFEEYLENGKVSFGYRAATLQPILTLDVPLPLHILQEIDFPSRFNDLAASILRLRGDVCGYKAERSRGEEASSISCYMKDNPGATEEDALNQIDTMIKEKIKELNWEFLKPDSNVPISSKKHAFDILRAFYHLYKYRDGFSIANNETKSLVMRTLLETVPF
Protein: Phytochrome 1 (P36505)
Organism: Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens)
Function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenetic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion. Mediates chloroplast avoidance movement in cytoplasm.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17662030}.
Interaction partners:
Sequence:
MSTPKKTYSSTSSAKSKAHSVRVAQTTADAALQAVFEKSGDSGDSFDYSKSVSKSTAESLPSGAVTAYLQRMQRGGLTQSFGCMIAVEGTGFRVIAYSENAPEILDLVPQAVPSVGEMDTLRIGTDVRTLFTASSVASLEKAAEAQEMSLLNPITVNCRRSGKQLYAIAHRIDIGIVIDFEAVKTDDHLVSAAGALQSHKLAAKAITRLQALPGGDIGLLCDTVVEEVRELTGYDRVMAYRFHEDEHGEVVAEIRRADLEPYLGLHYPGTDIPQASRFLFMKNKVRIIADCSAPPVKVIQDPTLRQPVSLAGSTLRSPHGCHAQYMGNMGSIASLVMAVIINDNEEDSHGSVQRGRKLWGLVVCHHTSPRTVPFPLRSACGFLMQVFGLQLNMEVELAAQLREKHILRTQTLLCDMLLRDAPIGIVSQIPNIMDLVKCDGAALYYGKRFWLLGTTPTESQIKDIAEWLLEYHKDSTGLSTDSLADANYPAAHLLGDAVCGMAAAKITAKDFLFWFRSHTAKEIKWGGAKHDPGEKDDGRKMHPRSSFKAFLEVVKRRSLPWEDVEMDAIHSLQLILRGSFQDIDDSDTKTMIHARLNDLKLHDMDELSVVANEMVRLIETATAPILAVDSNGMINGWNAKIAQVTGLPVSEAMGRSLVKDLVTDESVAVVERLLYLALRGEEEQNVEIKLKTFGTQTEKGVVILIVNACSSRDVSENVVGVCFVGQDVTGQKMFMDKFTRIQGDYKTIVQNPHPLIPPIFGADEFGYCFEWNPAMEGLTGWKKDEVVGKLLVGEIFGMQMMCCRMKSQDAMTKFMIALNTAMDGQSTDKFTFSFFDREGKYVDVLLSTNKRTNADGVITGVFCFLQIASSELQQALKVQRATEKVAVAKLKELAYIRQEIKNPLCGITFTRQLLEDTDLSDDQQQFLDTSAVCEQQLQKVLNDMDLESIEDGYLELDTAEFEMGTVMNAVISQGMTTSREKGLQIFRETPREINTMRLLGDQIRLQQVLSDFLLNTVRFTPSPEGWVKIKVVPTRKRLGGSVHVVHLEFRVSHPGAGLPEELVLEMYDRGKGMTQEGLGLNMCRKLVRLMNGDVHYVREAMQCYFVVNVELPMAQRDDASSQM
Protein: Protein DETOXIFICATION 45, chloroplastic (AtDTX45) (Multidrug and toxic compound extrusion protein 45) (MATE protein 45) (Q9SVE7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- AT4g17070/dl4565c
- RING-type E3 ubiquitin transferase
Sequence:
MESSRVVVGGGLPLANRRNSSFAKPKIQQGTFLPLSRINNVSAPQKCSLHTNPNPMFPFVTRRKSQTNPDCGVVKLGEEDDSCSSLDKLPEVNGVHTGVARPVDIKRELVMLSLPAIAGQAIDPLTLLMETAYIGRLGSVELGSAGVSMAIFNTISKLFNIPLLSVATSFVAEDIAKIAAQDLASEDSQSDIPSQGLPERKQLSSVSTALVLAIGIGIFEALALSLASGPFLRLMGIQSMSEMFIPARQFLVLRALGAPAYVVSLALQGIFRGFKDTKTPVYCLGIGNFLAVFLFPLFIYKFRMGVAGAAISSVISQYTVAILMLILLNKRVILLPPKIGSLKFGDYLKSGGFVLGRTLSVLVTMTVATSMAARQGVFAMAAHQICMQVWLAVSLLTDALASSGQALIASSASKRDFEGVKEVTTFVLKIGVVTGIALAIVLGMSFSSIAGLFSKDPEVLRIVRKGVLFVAATQPITALAFIFDGLHYGMSDFPYAACSMMVVGGISSAFMLYAPAGLGLSGVWVGLSMFMGLRMVAGFSRLMWRKGPWWFMHTSDKRLA
Protein: Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1)] (P01135)
Organism: Homo sapiens (Human)
Function: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Subcellular location: [Transforming growth factor alpha]: Secreted, extracellular space.; SUBCELLULAR LOCATION: [Protransforming growth factor alpha]: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Epidermal growth factor receptor
- Receptor tyrosine-protein kinase erbB-3
- Receptor tyrosine-protein kinase erbB-2
- Pro-epidermal growth factor
- Receptor tyrosine-protein kinase erbB-4
- Insulin-like growth factor 1
- Amphiregulin
- Insulin
- Platelet-derived growth factor subunit B
- Platelet-derived growth factor subunit A
Sequence:
MVPSAGQLALFALGIVLAACQALENSTSPLSADPPVAAAVVSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVLIHCCQVRKHCEWCRALICRHEKPSALLKGRTACCHSETVV
Protein: Chromobox 3 (Chromobox homolog 3 (HP1 gamma homolog, Drosophila)) (Q5RJK5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Histone-lysine N-methyltransferase
- [histone H3]-lysine
- Polycomb group RING finger protein 6
- E2F transcription factor 6
- Lethal
- Histone H3.3
- Transcription intermediary factor 1-beta
- Histone H3.1
- Histone H3
- Lethal
Sequence:
MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ
Protein: Dihydro-heme d1 dehydrogenase (EC 1.3.-.-) (Q9I609)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in heme d1 biosynthesis. Catalyzes the introduction of a double bond into the propionate side chain of pyrrole ring D of dihydro-heme d1, therefore converting dihydro-heme d1 to heme d1.
Subcellular location: Periplasm {ECO:0000305|PubMed:25204657}.
Interaction partners:
- Siroheme decarboxylase NirL subunit
- Pre-heme d1 synthase
- Cytochrome c55X
- Siroheme decarboxylase NirG subunit
- Siroheme decarboxylase NirH subunit
- Siroheme decarboxylase NirD subunit
- Cytochrome c-551
- Protein NirF
- Nitrite reductase
- Nitric oxide reductase subunit B
Sequence:
MRLIGLALGLLLGALAQAGEAPGEALYRQHCQACHGAGRLGGSGPTLLPESLSRLKPAQAREVILHGRPATQMAGFAGQLDDAAADALVAYLYQAPPREPQWSAEDIRASQVQPHPLATLPSRPRFEADPLNLFVVVESGDHHVTILDGDRFEPIARFPSRYALHGGPKFSPDGRLVYFASRDGWVTLYDLYNLKVVAEVRAGLNTRNLAVSDDGRWVLVGNYLPGNLVLLDARDLSLVQVIPAADAQGQASRVSAVYTAPPRHSFVVALKDVHELWELPYANGKPVAPKRLAVADYLDDFSFSPDYRYLLGSSRQARGGEVIELDSGARVASIPLSGMPHLGSGIYWKRDGRWVFATPNISRGVISVIDLQNWKPLKEIVTDGPGFFMRSHADSPYAWTDTFLGKKHDEILLIDKQTLEIAHRLRPSPGKVAGHVEFTRDGRYALLSVWDRDGALVVYDAHSLEEVKRLPMNKPSGKYNVGNKIGYAEGTSH
Protein: RNA-binding KH domain-containing protein PEPPER (Q9SZH4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates vegetative and gynoecium development. In concert with HUA2, antagonizes FLK by positively regulating FLC probably at transcriptional and post-transcriptional levels, and thus acts as a negative regulator of flowering.
Subcellular location: Nucleus {ECO:0000269|PubMed:19576878}.
Interaction partners:
- At5g19300
- AGAMOUS-like 77
- AGAMOUS-like 87
- AGAMOUS-like 91
- Glutaminyl-peptide cyclotransferase
- Protein SIEVE ELEMENT OCCLUSION A
- Elicitor peptide 4
- Protein kinase superfamily protein
Sequence:
MAAVADSVENNGSINLPENENLIPAGFSAAALLDENSGAFPELNQPDSLAAAETTFPDTNDSAEERWPGWPGDCVFRMIVPVTKVGAIIGRKGDFIKKMCEETRARIKVLDGPVNTPDRIVLISGKEEPEAYMSPAMDAVLRVFRRVSGLPDNDDDDVQNAGSVFSSVRLLVASTQAINLIGKQGSLIKSIVENSGASVRILSEEETPFYAAQDERIVDLQGEALKILKALEAIVGHLRRFLVDHTVVPLFEKQYLARVSQTRQEEPLAESKSSLHTISSNLMEPDFSLLARREPLFLERDSRVDSRVQPSGVSIYSQDPVLSARHSPGLARVSSAFVTQVSQTMQIPFSYAEDIIGVEGANIAYIRRRSGATITIKESPHPDQITVEIKGTTSQVQTAEQLIQEFIINHKEPVSVSGGYARIDSGYVPAYPPQLSNRQEPLPSTYMGTEPVQYRPTAYSQLGGPSTYTPTLTGQTYGSEYRPASDVGGYSSYNL
Protein: SigmaB regulation protein RsbU, putative (Q2FWJ1)
Organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)
Interaction partners:
- Anti-sigma-B factor antagonist
- Serine-protein kinase RsbW
- SigmaB regulation protein RsbU, putative
- RNA polymerase sigma factor
Sequence:
MSYKKFGYSYRDYQRLVDKLQVHDKEIDLASSLQQTMLKTDIPQFDSIQIGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPAALAMSMIKFGMDSYGHSQLPSDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCSSAGHEPGYIYRAEKEEFEEISVRGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEARNSEGTFIDKQKLLEYIKKHKHMHPQDIVQIIYEAILKLQNPNKKDDMTILIIKRVN
Protein: GTP 3',8-cyclase 1 (EC 4.1.99.22) (Molybdenum cofactor biosynthesis protein A 1) (P9WJS3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
Interaction partners:
- Cyclic pyranopterin monophosphate synthase 2
- Cyclic pyranopterin monophosphate synthase 3
- Cyclic pyranopterin monophosphate synthase 1
- Molybdopterin synthase sulfur carrier subunit
- Molybdopterin synthase catalytic subunit 2
- Putative pterin-4-alpha-carbinolamine dehydratase
- Molybdopterin synthase catalytic subunit 1
- Molybdopterin synthase catalytic subunit 1
- GTP 3',8-cyclase 2
- MoaB/Mog domain-containing protein
Sequence:
MSTPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKVRITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRIEPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLREPLRAGATHDDLVETVTTGWRRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
Protein: Protein SPT2 (Negative regulator of Ty transcription) (P06843)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription. Global regulatory protein that plays positive as well as negative regulatory roles in transcription.
Subcellular location: Nucleus {ECO:0000269|PubMed:2072912, ECO:0000269|PubMed:26109053}.
Interaction partners:
- RNA polymerase-associated protein LEO1
- Histone H3
- Transcription elongation factor SPT6
- Cell division control protein 73
- Histone chaperone ASF1
Sequence:
MSFLSKLSQIRKSTTASKAQVQDPLPKKNDEEYSLLPKNYIRDEDPAVKRLKELRRQELLKNGALAKKSGVKRKRGTSSGSEKKKIERNDDDEGGLGIRFKRSIGASHAPLKPVVRKKPEPIKKMSFEELMKQAENNEKQPPKVKSSEPVTKERPHFNKPGFKSSKRPQKKASPGATLRGVSSGGNSIKSSDSPKPVKLNLPTNGFAQPNRRLKEKLESRKQKSRYQDDYDEEDNDMDDFIEDDEDEGYHSKSKHSNGPGYDRDEIWAMFNRGKKRSEYDYDELEDDDMEANEMEILEEEEMARKMARLEDKREEAWLKKHEEEKRRRKKGIR
Protein: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Q5F488)
Organism: Gallus gallus (Chicken)
Function: Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
Interaction partners:
Sequence:
MSKTLRKKRHWLSKVQECVVSWGGPAGPDPELLHGGAERGEFPYLAGRLPTGAEGAPGPALLSGKAPAPGDVLLEVNGTPVSGLTHRDTLAVIRHFREPVRLKTVRPGKVINKDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFIPVEQFKALEESGALLESGTYDGNFYGTPKPPAEPSPFQPDPVDQVLFDNDFDTESQRKRTTSVSKMQRMDSSLPEDEEEEEKEAVNGSGGIENKEKHSDSSDWMKPVPSYNQTSSSMDFRNYMSRDETLEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIEDPQYGTYYVDHINQKTQFENPVLEAKRKKQLGQTDGGPSKSVPEKSLFTRDPSQLIGALIRTSLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGRIAPGDVIVDINGNCVLGHTHADVVQMFQLVPVNQYVNMTLCRGYPLPDDNEDPVVDIVTATPIINGPPVTKGDICLTSQELIAGTVVLDQNGKTGPMLVNGRLNGPSMDTNEQRISVASSGGSQPELVTIPLVKGPKGFGFAIADSPTGQKVKMILDSQWCQGLQKGDVIKEICHQNVQSLTHLQVVEVLKQFPIGAEVPLLILRGGPPSPTKTGKMKDKQESSGSLEALSDAIPQPMPFPPTAVRSGSPKLDPSEVYLKSKTMYEDKPPNTRDLDVFLRKQESGFGFRVLGGDGADQPIYIGAIIPLGAAEKDGRLRAADELMCIDGVPVKGKSHKQVLDLMTSAARNGQVLLTVRRKIFFGGEKQAEEDESQAVVTQNSSPRLNRAEFATQQSPEVYDVCLQRKENEGFGFVILTSKNKPPPGVIPHKIGRVIDGSPADQCGKLKVGDRISAVNGQSIVELSHDSIVQLIKDAGHVVTLTVVAEEEHRGPPSGTNSAKQSPAPQHRPLGPAQSSASSTDRGATEGEAGKEVSNSYRLSWPEHKHLAQPDAGSASGVGSRHSQAQNSGCFPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAVKDGRVHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHSLAPSSLCPYVKPEQH
Protein: GEO08966p1 (GH24739p) (Glutaredoxin 1, isoform A) (Glutaredoxin 1, isoform C) (Q9VVT6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ribonucleoside-diphosphate reductase large subunit
- LD40224p
- Thioredoxin reductase 1, mitochondrial
- P-type Cu
- Glutaredoxin-related protein 5, mitochondrial
Sequence:
MGAVGSALRSPIVDMSTKQAKFVENTIASNKVVIFSKTYCPYCTMAKEPFKKLNVDATIIELDGNPDGNEIQAVLGEITGARTVPRVFIDGKFIGGGTDIKRMFETGALQKYFQ
Protein: Bifunctional L-3-cyanoalanine synthase/cysteine synthase D2 (EC 2.5.1.47) (EC 4.4.1.9) (Beta-substituted Ala synthase 4;2) (ARAth-Bsas4;2) (Cysteine synthase D2) (AtcysD2) (O-acetylserine (thiol)-lyase 6) (Q9SXS7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a cysteine synthase. The cysteine synthesis reaction is more efficient than the cyanoalanine synthase activity.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:10845460}.
Interaction partners:
- Assimilatory sulfite reductase
- Cystathionine gamma-synthase 1, chloroplastic
- Probable cystathionine gamma-synthase 2
- Cystathionine beta-lyase, chloroplastic
- Methionine gamma-lyase
- L-cysteine desulfhydrase
- Probable L-cysteine desulfhydrase, chloroplastic
- Phosphoserine aminotransferase 1, chloroplastic
- Adenosylhomocysteinase 2
- Adenosylhomocysteinase 1
Sequence:
MEDRCLIKNDITELIGNTPMVYLNNVVDGCVARIAAKLEMMEPCSSVKDRIAYSMIKDAEDKGLITPGKSTLIEPTAGNTGIGLACMGAARGYKVILVMPSTMSLERRIILRALGAELHLSDQRIGLKGMLEKTEAILSKTPGGYIPQQFENPANPEIHYRTTGPEIWRDSAGKVDILVAGVGTGGTATGVGKFLKEQNKDIKVCVVEPVESPVLSGGQPGPHLIQGIGSGIVPFNLDLTIVDEIIQVAGEEAIETAKLLALKEGLLVGISSGAAAAAALKVAKRPENAGKLIVVVFPSGGERYLSTKLFDSIRYEAENLPIE
Protein: Retinoic acid receptor responder protein 1 (Phorbol ester-induced gene 1 protein) (PERG-1) (RAR-responsive protein TIG1) (Tazarotene-induced gene 1 protein) (P49788)
Organism: Homo sapiens (Human)
Function: Inhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle.
Subcellular location: Membrane {ECO:0000269|PubMed:21303978}; Single-pass type III membrane protein {ECO:0000269|PubMed:21303978}. Secreted {ECO:0000269|PubMed:36213313, ECO:0000269|PubMed:37453717}.
Interaction partners:
Sequence:
MQPRRQRLPAPWSGPRGPRPTAPLLALLLLLAPVAAPAGSGDPDDPGQPQDAGVPRRLLQQAARAALHFFNFRSGSPSALRVLAEVQEGRAWINPKEGCKVHVVFSTERYNPESLLQEGEGRLGKCSARVFFKNQKPRPTINVTCTRLIEKKKRQQEDYLLYKQMKQLKNPLEIVSIPDNHGHIDPSLRLIWDLAFLGSSYVMWEMTTQVSHYYLAQLTSVRQWKTNDDTIDFDYTVLLHELSTQEIIPCRIHLVWYPGKPLKVKYHCQELQTPEEASGTEEGSAVVPTELSNF
Protein: tRNA(cytosine(8)) deaminase (EC 3.5.4.35) (Cytidine deaminase acting on tRNA base C8) (CDAT8) (Q8TWU6)
Organism: Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Function: Catalyzes the deamimation of cytosine to uracil at position 8 of tRNA in 30 different tRNAs. This editing guarantees the proper folding and functionality of the tRNAs.
Interaction partners:
- Glutamine--fructose-6-phosphate aminotransferase
- tRNA sulfurtransferase
- Probable ribosomal RNA small subunit methyltransferase A
- Predicted hydrolase of the metallo-beta-lactamase superfamily, contains a Zn-ribbon
- Topoisomerase V
- tRNA
- Reverse gyrase subunit B
- Reverse gyrase subunit A
Sequence:
MKVSLAGQTVDVKKILNEIPKRTVTAALLEGGEIVAVEEADDEHAERKLVRRHDVEGKVVFVTARPCLYCARELAEAGVAGVVYLGRGRGLGPYYLARSGVEVVEVHPDEPLGYDPVDRLDVLLTFGGNPYLTEEDVAARVYCLLTGRGFDADIAPAPENLSGRVEIMVTRGDPDEAVELLKEELPVFRIRRFLISGEFDRDELRERILEDIEPRILDPFAVRARIARAGAFSSSREAEVFIGDVLTSVGREVNLNDPRTVVTVDVLGPRVSVGVEKR
Protein: Small ribosomal subunit protein uS15m (28S ribosomal protein S15, mitochondrial) (MRP-S15) (S15mt) (P82914)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:27184847}.
Interaction partners:
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein bS6m
- Large ribosomal subunit protein bL21m
- Small ribosomal subunit protein mS25
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL33m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein mS27
- Small ribosomal subunit protein uS12m
Sequence:
MLRVAWRTLSLIRTRAVTQVLVPGLPGGGSAKFPFNQWGLQPRSLLLQAARGYVVRKPAQSRLDDDPPPSTLLKDYQNVPGIEKVDDVVKRLLSLEMANKKEMLKIKQEQFMKKIVANPEDTRSLEARIIALSVKIRSYEEHLEKHRKDKAHKRYLLMSIDQRKKMLKNLRNTNYDVFEKICWGLGIEYTFPPLYYRRAHRRFVTKKALCIRVFQETQKLKKRRRALKAAAAAQKQAKRRNPDSPAKAIPKTLKDSQ
Protein: Major envelope glycoprotein (gp64) (P17501)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: Class III viral fusion protein. Envelope phosphoglycoprotein which mediates the fusion of viral and host endosomal membranes leading to virus entry into the host cell. After receptor-mediated internalization of the virus, gp64 undergoes conformational change into a fusion-competent state at low pH, and the nucleocapsid is released into the cytoplasm after cell fusion. May also play role in budding.
Subcellular location: Virion membrane {ECO:0000269|PubMed:25142609}; Single-pass membrane protein {ECO:0000305}. Host cell membrane {ECO:0000269|PubMed:12743283}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MVSAIVLYVLLAAAAHSAFAAEHCNAQMKTGPYKIKNLDITPPKETLQKDVEITIVETDYNENVIIGYKGYYQAYAYNGGSLDPNTRVEETMKTLNVGKEDLLMWSIRQQCEVGEELIDRWGSDSDDCFRDNEGRGQWVKGKELVKRQNNNHFAHHTCNKSWRCGISTSKMYSRLECQDDTDECQVYILDAEGNPINVTVDTVLHRDGVSMILKQKSTFTTRQIKAACLLIKDDKNNPESVTREHCLIDNDIYDLSKNTWNCKFNRCIKRKVEHRVKKRPPTWRHNVRAKYTEGDTATKGDLMHIQEELMYENDLLKMNIELMHAHINKLNNMLHDLIVSVAKVDERLIGNLMNNSVSSTFLSDDTFLLMPCTNPPAHTSNCYNNSIYKEGRWVANTDSSQCIDFSNYKELAIDDDVEFWIPTIGNTTYHDSWKDASGWSFIAQQKSNLITTMENTKFGGVGTSLSDITSMAEGELAAKLTSFMFGHVVNFVIILIVILFLYCMIRNRNRQY