wanglab/gogpt-training-data huggingface dataset:
Protein: Multidrug transporter TPO1_1 (Clotrimazole exporter TPO1_1) (Drug:H(+) antiporter TPO1_1) (DHA TPO1_1) (Q6FTB1)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Multidrug resistance transporter involved in resistance to azole antifungal drugs such as the imidazoles miconazole, ketoconazole, and tioconazole; as well as the triazoles itraconazole and fluconazole. Also plays a role in the resistance to other antifungal drug families such as the polyene amphotericin B, the pyrimide analog flucytosine, the fungicide mancozeb, and the polyamine spermine. Decreases the intracellular accumulation of clotrimazole by mediating its extrusion from cells. Involved in virulence by confering resistance to the human antimicrobial peptide histatin-5.
Subcellular location: Cell membrane {ECO:0000269|PubMed:26512119}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MVEEISPKYTNEQAEASSSSSSSVSGEPKDFSGSLENQEDLGELIERTNTMTSGAESKVETNRRMSRILTGTQDDPEKIAIDYSNCPPMGGDRPFPPALPEQSQFEVTFDGPNDPIHPFNWSMKTKTIICIVLCLNCICISMGSSIFASGVPQICKIYHVIPVVAILGVTLYVFGFAASPVIYAPLSEVYGRRGVLVISAFGFAVFQFAVATSKDLQSIMICRFFGGLIGAAPMAVVPAAFADMFDVRVRGKAICLFSLGVFVGPILSPVMGSYIAQRTTWRWLEYVTGCFASALFVAVALTFKETHHPTILVQKAKEMRKSTNNWGIHAAHEHVELSVSEIAKKTITRPIKMLFTEPLLLIITIYNSFVYGILYLMLEAYPIVFVEGYGFEANGELPYIALIIGMLVCTAFLWYFENDYLKRIQKAGKLVPEARLIPMVYAGVIFPIGILWFCWTGYYPHKIHWMCPTVAGSFIGFGLMGIFLPCLNYIIESYLPLAASAVAANTFMRSAFGAVFPLFAGYMFHGMGTGWAGLLLGLFAAALIPVPLFFLKYGERIRKNSKDAYYA
Protein: Uracil phosphoribosyltransferase 1 (UPRTase 1) (EC 2.4.2.9) (UMP pyrophosphorylase 1) (O13867)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
Interaction partners:
- Uridine kinase
- Orotidine 5'-phosphate decarboxylase
- Uridylate kinase
- Putative purine nucleoside phosphorylase
- Putative uracil phosphoribosyltransferase urg2
- Golgi apyrase
- Uracil phosphoribosyltransferase 2
- Pseudouridine-metabolizing bifunctional protein C1861.05
- Zinc finger chaperone zpr1
Sequence:
MSLVPEHGNVYVLNQTNQLKGLFTIIRDKTKPRSEFIFYANRIIRLIVEEGLNHLPVSSAKVTTAQNAEYEGVMFDGRICGVSIMRAGESMEQGLRECCRSVRIGKILIQRDEETHKPVLHYIKLPEDISKRYVLLLDPMLATGGSAICAMEILINMGCKQEQIIFLNVIASPEGLKNVHDRFPNIRIVTAVIDEGLDNNGYIVPGLGDFGDIYFGTKA
Protein: Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain] (P10619)
Organism: Homo sapiens (Human)
Function: Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
Subcellular location: Lysosome.
Interaction partners:
- Beta-galactosidase
- Sialidase-1
- Elastin
- Cathepsin D
- Sialidase-4
- Cathepsin S
- Cathepsin B
- Ubiquitin-like protein NEDD8
- N-acetylgalactosamine-6-sulfatase
- Adenosine 5'-monophosphoramidase HINT1
Sequence:
MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY
Protein: Dynein axonemal intermediate chain 1 (A0A0D9RCF4)
Organism: Chlorocebus sabaeus (Green monkey) (Simia sabaea)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}.
Interaction partners:
- Dynein axonemal heavy chain 5
- Dynein axonemal heavy chain 7
- Dynein axonemal heavy chain 1
- Dynein axonemal heavy chain 11
- Radial spoke head component 4A
- Thioredoxin domain-containing protein 3
- Dynein regulatory complex subunit 2
- Dynein axonemal heavy chain 9
- Dynein axonemal heavy chain 10
- Dynein axonemal heavy chain 17
Sequence:
MKSIYLSPKSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDAELKEEFTRILTANNPHAPQNIVRYSFKEGTYKLIGFVNQLAVHYTQVGNLIPKDSDEGRRQHYRDELVAGSQESAKVISETENLEEDEEPKELETESGSQTDVPAAGAAEKVTEEELMTPKQPKERKLTNQFNFSERASQTFNNPLRDRECQMEPPPRTNFSATANQWEIYDAYIEELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDIIKVSQAAKIVERMVNQNTYDEVAQDFKYYEDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGHGSYDFMKQSRGMLLLYSMKNPSFPEYMFSSDSGIMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQPSFRSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKSELVHVDVIKLKVEGSTTEVPEGLQLHTVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHNMAVDAVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAAVTTDGKAHVFDLAINKYEAICNQPVAAKKKNKITHVQFNPIHPIIIVGDDRGHIICLKLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
Protein: Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK (EC 4.2.-.-) (P0AAR3)
Organism: Escherichia coli (strain K12)
Function: Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Proline--tRNA ligase
- Uncharacterized protein YbaP
- Threonine--tRNA ligase
- Multifunctional Ser/Thr-tRNA deacylase ProXp-y
- Leucine--tRNA ligase
- Isoleucine--tRNA ligase
Sequence:
MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQVYKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGGISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD
Protein: Neurotrophic factor BDNF precursor form (proBDNF) (Brain-derived neurotrophic factor) [Cleaved into: Neurotrophic factor BDNF] (P25429)
Organism: Gallus gallus (Chicken)
Function: Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P23560}.
Interaction partners:
- BDNF/NT-3 growth factors receptor
- NT-3 growth factor receptor
- Glial cell derived neurotrophic factor.
- High affinity nerve growth factor receptor
- Ciliary neurotrophic factor
- Sortilin.
- Neurotrophin-3
- cAMP response element-binding protein
- Fibroblast growth factor 2
- Methyl-CpG binding protein 2.
Sequence:
MTILFLTMVISYFSCMKAAPMKEASVRGHGSLAYPGLRTHGTLESLTGPNAGSRGLTSLADTFEHVIEELLDEDQDIQPSEENKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSTSEWVTAAEKKTAVDMSGATVTVLEKVPVPKGQLKQYFYETKCNPKGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDNKKRVGWRFIRIDTSCVCTLTIKRGR
Protein: Uncharacterized AAA domain-containing protein C24B10.10c (Q9P7J5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 6
- ERMES regulator 1
- Putative endoplasmic reticulum metallopeptidase 1
- Translation initiation factor IF-2, mitochondrial
- Cytochrome c oxidase subunit 4, mitochondrial
Sequence:
MNPTTKRAIKEIVVYALAFGCSWYAAHKLLSTLDPYRQKRQDTVSKSRKRLDEWAGEQVKELETLELNEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEAIRRRMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSALSVPRRELFDKHGNDLEAIKYDIQSGGLRSLKTEDFYHYESLQNVSGIDVE
Protein: Small ribosomal subunit protein eS32A (60S ribosomal protein L41-A) (L47) (Large ribosomal subunit protein eL41A) (YL41) (P0CX86)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Ribosome biogenesis protein NOP53
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS14B
- Large ribosomal subunit protein eL39
- Small ribosomal subunit protein uS7
- Eukaryotic translation initiation factor 5A-1
- Small ribosomal subunit protein uS14A
- Elongation factor 2
- Large ribosomal subunit protein eL29
- Eukaryotic translation initiation factor 2 subunit beta
Sequence:
MRAKWRKKRTRRLKRKRRKVRARSK
Protein: Heterogeneous nuclear ribonucleoprotein 27C (Hrb27-C) (HRP48.1) (hnRNP 48) (P48809)
Organism: Drosophila melanogaster (Fruit fly)
Function: This protein is a component of ribonucleosomes. Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle.
Subcellular location: Nucleus. Cytoplasm. Note=Nuclear and/or cytoplasmic.
Interaction partners:
- RNA-binding protein squid
- Protein gurken
- Polyadenylate-binding protein
- Zinc finger CCCH domain-containing protein 14
- Deubiquitinase otu
- Maternal effect protein oskar
- Cleavage stimulation factor 64 kD subunit
- AT27789p
- RNA-binding protein Unr
- Poly
Sequence:
MEEDERGKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQNGPHTLDGRTIDPKPCNPRTLQKPKKGGGYKVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMYDQEKKKSRGFGFLSFEEESSVEHVTNERYINLNGKQVEIKKAEPRDGSGGQNSNNSTVGGAYGKLGNECSHWGPHHAPINMMQGQNGQMGGPPLNMPIGAPNMMPGYQGWGTSPQQQQYGYGNSGPGSYQGWGAPPGPQGPPPQWSNYAGPQQTQGYGGYDMYNSTSTGAPSGPSGGGSWNSWNMPPNSAGPTGAPGAGAGTATDMYSRAQAWATGGPSTTGPVGGMPRTGPGNSASKSGSEYDYGGYGSGYDYDYSNYVKQEGASNYGAGPRSAYGNDSSTQPPYATSQAV
Protein: Small ribosomal subunit protein uS11c (30S ribosomal protein S11, chloroplastic) (P0C463)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS8c
- Small ribosomal subunit protein uS7cz/uS7cy
- Small ribosomal subunit protein uS12cz/uS12cy
- Uncharacterized protein
- Small ribosomal subunit protein uS14c
- Large ribosomal subunit protein uL16c
- Small ribosomal subunit protein uS2c
- S5 DRBM domain-containing protein
- Large ribosomal subunit protein mL46
- Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein
Sequence:
MTKAIPKIGSRRKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
Protein: G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5) (P48548)
Organism: Rattus norvegicus (Rat)
Function: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Subcellular location: Membrane {ECO:0000269|PubMed:7877685}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- G protein-activated inward rectifier potassium channel 1
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid type B receptor subunit 1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- G protein-activated inward rectifier potassium channel 3
Sequence:
MAGDSRNAMNQDMEIGVTSQDHKKIPKQARDYIPIATDRTRLLPEGKKPRQRYMEKTGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTITWLFFGFIWWLIAYVRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRAQLEQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKRNGQLLQSLPSPPLLGGCAEAEKEAEAEHDEEEEPNGLSVSRATRGSM
Protein: Alkylsulfatase (EC 1.14.11.-) (Q6FBW1)
Organism: Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Function: Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the oxygenolytic release of sulfite from hexylsulfate.
Interaction partners:
- Sulfate ester binding protein
Sequence:
MTTFIQNPTQQLQLRKLTGRIGAEISGIHLSSELDSSTVQFIHDALLEHKVLFFRGQQHLGDTEQEKFAELFGSPVKHPTVPAADGTDFIFELDSQKGARANSWHTDVTFVDAYPKISILRGLIIPETGGDTTWANTETAYEDLPELLKQFAEQLVAVHSNEYDYGGPKQNVEPEQLERLKKVFVSTKYETEHPVVIVHPETGKKSLLLGHFFKRLVGFSQSDSQLLFNILQEKVTRPENTVRWQWQEGDVVIWDNRSTQHYAVNDYGDQHRVVRRITLAGEVTTGAHGLKGKTTLPKDLSAEQLEKAKLHAVLNAN
Protein: Protein PLASTID MOVEMENT IMPAIRED 1-RELATED 1 (F4K5K6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Together with PMI1, necessary for chloroplast and nuclear photorelocation movements via the regulation of chloroplast-actin (cp-actin) filaments in pavement cells.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:26324877}.
Interaction partners:
- Protein WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT 1
- Protein CHUP1, chloroplastic
- J domain-containing protein required for chloroplast accumulation response 1
- Kinesin-like protein KIN-14A
- Uncharacterized protein At1g66480
- Protein PLASTID MOVEMENT IMPAIRED 15
Sequence:
MSKVNSEESSSSQKLLKEVEKISEALYVNKNPRGSVAGSNKTPTKPLSRSNLAEPKEKKSFWNWPLRAINHVRNRRFNCCFSAQVHSIEGLPPIFQDLSLTVHWKRRDESLSTRPAKVSNGRAEFKDKLTHTCSVYGSRSGPHHSAKYEAKHFLLYVSLVGSPEIDLGKHRMDLTKLLPLTLEELQDEKSSGKWSTTFQLSGKANGATLSMSFGYTVVGDTRNPASSGSTQNFRSSSNVKQTSNNTGLTRAISAKSSLGNGKSASRRYDHSIVNRESHPLSQNMEEIKDLHEILPAVQSDLGSSVNTLYQKFDEEKVDPANESQFEFDVVTKHIEPVESISHEKEDANALQSELVTGNETVVPFEEIKKAGEVPTAGSDEVGAENFPLEEPLVNGNETDVPFELLKKAGEVPTAGRDEVGTEILPPEEPLVNGNETDVPFEELMITGEASIARSEEAVEIVTEELAPEEGNKISPKNEESVVPKDAEEVMNGEKDLKEMIMKDLESALKSVEMLEATASEDEEDRKKHGDKDKYFITPMKETVPSCSRDVAESVACEFLDMLGIEHSPFGLSSESEPESPRERLLREFEMETLAAGSLFDFSIEGDDPQLECDENFPNEYESDFEEGFDLASLVHDIEEEYQLEAQARVSHPRAKMLEGLETESLMREWGMNENTFQNSPPHNGRDAFHPADFPVKEPFDLPPLGDGLGPVVQTKNGGFLRSMNPLLFRNSKAGGSLIMQVSTPVVVPAEMGSGIMEILQKLATAGIEKLSMQANKVMPLDDITGKTMEEVLWETSPTIDIGDRDHVSERESGDASGFVRGGERRTSFAAKPKKFGSSSGNNNFDSEYVSLEDLAPLAMDQIEALSLEGLRIQSGMSDEDAPSDITAQSIGDISAFQGKSGCVGLEGAAGLQLLDIKDDGDDDDDGLMGLSLTLDEWMKLDSGDIGDEDEINERTSKILAAHHANPLNFIRKGSKGEKRKGKKGRKCGLLGNTFTVALMVQLRDPLRNYEPVGAPMLSLIQVERLFVPPKPKIYSTVSELKKTDEEEEADASDAKKEEKPMEEQGIPQYKITEVHLTGMKSETDKKPWGITTQQQQVQSGSRWLMANGMGKGNNKLPLMKPKLGSAKPGDKLWSVSGSGSKWKELGKMGKSNTHIRNPNVIMPK
Protein: Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (B0BN39)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364150}.
Interaction partners:
Sequence:
MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKIVVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMRNFAEQLKPLVHLEKIDPKRLM
Protein: MADS box protein GHMADS-2 (MADS-box protein MADS6) (Q8H6F8)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRGKIEIKRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYSNNNIRSTIDRYKKACSDTSNTNTVTEINAQYYQQESAKLRQQIQMLQNSNRHLMGDSLSSLTVKELKQVENRLERGITRIRSKKHEMLLAEIEFLQKREIELENESVCLRTKIAEIERLQQANMVTGPELNAIQALASRNFFSPNVIEHPSAYSHPSDKKILHLG
Protein: Small ribosomal subunit protein uS7cz/uS7cy (30S ribosomal protein S7, chloroplastic) (P0C490)
Organism: Oryza sativa subsp. indica (Rice)
Function: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS12cz/uS12cy
- Uncharacterized protein
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS2c
- Small ribosomal subunit protein uS9c
- 40S ribosomal protein S30
- 40S ribosomal protein S15
- Uncharacterized protein
- S5 DRBM domain-containing protein
Sequence:
MSRRGTAEKRTAKSDPIFRNRLVNMVVNRIMKDGKKSLAYQILYRAVKKIQQKTETNPLLVLRQAIRRVTPNIGVKTRRNKKGSTRKVPIEIGSKQGRALAIRWLLEASQKRPGRNMAFKLSSELVDAAKGGGGAIRKKEATHRMAEANRALAHFR
Protein: alanine transaminase (EC 2.6.1.2) (Q8T9D5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSRMLIKPAAATVSAALQQHQRQQQQYVIRRWKSFLHNNSNNANRRAAKSTATATVTAAATSQRHGTSGDFIQPLDVRRSFSTSHKMPSSSKALTLDNINPNFIAMEYAVRGPLVIRAGEIEKELEKGVKKPFDQVIRANIGDCHAMGQQPLTFLRQLLALTFEKRLLDSPDYPEDVKKRACAILNGCQGQSVGSYTDSAGLEVVRRQVAQYIEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPGVMVPIPQYPLYSATISEYGMTKVDYYLEEETGWSLDRKELQRSYDEAKKVCNPRALVVINPGNPTGQVLTRENIEEIIKFAHDNKVLVLADEVYQDNVYDKNSKFWSFKKVAYEMGDPYRNLEMVSFLSTSKGYLGECGIRGGYMEVLNLDPKVKAMLTKSITAALCSTTAGQVAVSALVNPPQPGEPSYDLYKKERDGILAALKERAELVHKALNSFEGYKVNPVQGAMYVFPQIEIPPKAIEAAKAKGMAPDVFYAFELLETSGICIVPGSGFGQKPGTWHFRSTILPQTDKLKLMMEKFRVFHAEFMKKYK
Protein: Pho114p (Q5AMR2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MVGLSRVLNAGFILSGQSVFQDVAAPHQASIEQYNIVKYLGGSGPYIQNSGYGISTDIPEKCTIEQVQMISRHGERFPSKGDGKYFNSVMEVFKRYGEFHGDLSFLNDYEYFVTNPDYYEKETTPKNSKGPYFGTTNLLRHGAYFRKRYQSLFDQKEKLVVFTSNSGRCYQSGVYFARGFLGDDYSEDTVEFVVVDEDKKMGGNSLTPRYACKTLNQDLHKDLVNQYDKTYLDDILSRWLVDNPGLDLSADQVSSLFLWCAFEINVRGYSPFCNLFTKDEFIRSGYRNDVGNYYQTGPGNNMTKVIGSPMVEASLKMLQEDSKIWLTFTHDTDIEMYLTSLGLIVPPGDLPVDRVPFPNPYNAAEFFPQGARTYTEKLKCGEKQYVRFIVNDAVYPYPDCSGGPGFTCELNDFIKLVKSRLHDVDYKLQCEVDGPAELTFYWDYKDRKYNAPLIDQ
Protein: Putative lipase ATG15 (EC 3.1.1.3) (Autophagy-related protein 15) (Cytoplasm to vacuole targeting protein 17) (P25641)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.
Subcellular location: Endosome, multivesicular body membrane {ECO:0000269|PubMed:12499386}; Single-pass type II membrane protein {ECO:0000269|PubMed:12499386}. Prevacuolar compartment membrane {ECO:0000269|PubMed:12499386}; Single-pass type II membrane protein {ECO:0000269|PubMed:12499386}. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC). {ECO:0000269|PubMed:12499386}.
Interaction partners:
- Serine/threonine-protein kinase ATG1
- Triacylglycerol lipase 3
- Autophagy protein 5
- Autophagy-related protein 18
- Ubiquitin-like modifier-activating enzyme ATG7
- Triacylglycerol lipase 4
- Autophagy-related protein 8
- Cysteine protease ATG4
- Ubiquitin-like protein ATG12
- Vacuolar protein sorting-associated protein 30
Sequence:
MLHKSPSRKRFASPLHLGCILTLTVLCLIAYYFALPDYLSVGKSSSRGAMDQKSDGTFRLKSIYRHGVGANHRLHQRLEVTPEVISAAGMLYQETTTQGQDFEDQEPLWTTNAEYATTNPFDFEFELRRMPLLMKRMKERDPEFIESYIYGETYMTEEEEHAMWIDDDIVAPNITDRGTVVSLALMSSNAYVRIPQTGDWRNVTEPWNETEPEDFGWDGDGIRGHVFYNEVENIVVLSIKGTSAQGLPGSGEDETTGNDKINDNLLFSCCCARVSYLWTTVCDCYVKSYICDESCLEKELRRKDRFYSAVVDIYKGVLKEYPDAAIWVTGHSLGGALASLLGRTFGLPAVAFESPGELLPSKRLHLPFPPGLPSYMEGIWHFGHNADPIFMGTCNGASSSCSLVGYAMETACHTGRVCVYDVVNDKGWSVNMFNHRIHKVIDEVLLGYEQAAKCVEPEPCVDCYNWKFIPSRDWESSSRLITKTKSHAAPTTTTRTTATTTSSSTCVGRNWLGFCTKYEL
Protein: Hepcidin (Q3YMZ8)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MRPMSIACAVAVIIACVCALQSAALPSEVRLDPEVRLEEPEDSEAARSIDQGVAAALAKETSPEVLFRTKRQSHLSLCRYCCNCCKNKGCGFCCRF
Protein: Serine/threonine protein phosphatase 2A regulatory subunit (Q5XH34)
Organism: Xenopus laevis (African clawed frog)
Interaction partners:
Sequence:
MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPTLEQPELFLKKLQQCGVIFDFMDTLSDLKMKEYKRSTLNELVDYVAISRGCLTEQTYPEAVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLIYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPTLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQISKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVVLPIMFASLYRISKEHWNPAIVALVYNVLKAFMEMNSTLFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRSDGIIPT
Protein: Protostome-specific GEF, isoform A (Q9W4Y9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPTMTRMHRHSSSSAVVEESRGRRRGVGVPGVGDANKENFGVHFMSSPFGNASLIALQDLSNVHGKSPQRRSFSEGSGPRQATPQLAALRCLPRTTGGAVALEDSQLSSSRMGDTTLDRMLDAIIESARKEVRCTKTLPGAGATTSTTILADNAEWSETSVHEMEVRTPTHLKRQRVVRRKNPHKTTTINQTQSHQAKKLEPLQLVPSTKRCLSFSSSSASSDLDEDEQQVAKRSSLASPTTTPPSHCTTTTSSISSSSSSNGGADMEASQRGSIDVSIAFDAKEQQLNVHVIRCRDLQRSHGSGNGSINAYVKVALSGGAQPPGYGGHSSGGSMSSGYQRTAVHRHSGRPYFDQRFNFQISSGEETAGQYLQLAVWHRDRHLNSVPVTQSEWQARVKSGTERRTAERLAKLENAGNEAKRSEFLGCSTFPLNELVHPDSGVSAGSYKLHAQACPPPTSRHSQPKANAGQDQKQETEAAKDQDKQQDDSPAEMAAAVTVTPQKPVATGSGSGSNSAAMALNDEVISISIDSMGKEDPLLPQQPQQPMKLSKKALHQRDADENLFLRFLELDPPADGNANSTTTQAQATGSQSSASKANESNANHLNNGTSGGRRQSTMPNSGGSSVGGAVRQQQGRTPFTMTKRLTRTEERGFGFSIVWTHPPRVEKIEAGLSADRCGILPGDYVIFVDKHNVVTMPEADVLNLIRSQGSSLTLEIFRRSGAGATTITSTDLGQNNVHISTRLGAAVGLGSEEHTLATTATGTTTVMSLQRTTSTRIQPLANSMSRPATACSGTTSSIEAAKRRLHLPQVTFSKESIVPVTDNRRRFLLQLISREQNFTAALHFGVDRFVQPLGERKDLISPNDHRTLFQNIDELLRIAEDILEQLCSSDQQDQEPQMNFASRVYLSKTTAICAAYKKYCNGIKRADCVLVNKSRQTGSEFIAFITEPAVPRKRPDLTMFIHRPLQHFREILKLMQLLAGNCHVDTEEHKNFSTVINELQAAYREITVSSGLMEPLGEGRPLLTLQDLESRMVFTKCKPFTLAVQGRQWIFGGDLSRVEGRSVKPYWTLLFSDIIVFAKVSRDRVLFITEEPIPIANVVDSCFHMRKKTTEFRLTVDPNGRLAESPTGYCAPDLTRTPKRGARRKSLILRAPSLELKAVWQNLLQRQIFLVNAALGSTPLSSPLDSPDVLNTLVPLSDIGLTTASMGSMKLPSLDSIHLKQQQKQQVRLFRSKRLDSGDSYENLQRLASAVRHHCASTTTSSATQTQSHPQPPLCTTSLPSRTNSPARNQRHPNGQGHVGGSVPNGVGGVSFGGCNTNSSCLSSSASLTQTQTQVHTQTLNHSQTHSQTQTSVLSLSSCKCLTVIPEVTSEPPVNQHASQKLLEFSLSSVGRSFIDESGGVVGGQVSLTTPETPTPNISPTTSQPCNSDAFSNDFVATSTTGKGPNIPLAEFGGSWDLLELDLQLHEVNLDPSYDTDVEECIFLGDEEDREGTEGHGHDEDSDEDDSVVVDDPFGMLPTRPTPPDSLDL