wanglab/gogpt-training-data huggingface dataset:
Protein: Expression site-associated gene (ESAG) protein, putative (Q38CS6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQRAATLIYTVIFVAVVLAPYFVAASGQVHGIQYGEAPVSSAPGSVKFAVDESVVTSAVPMVHRVLRQLIGNITVPEQSVQGIKLEEMQVSNITIGNMSLKLKSPNKLLVSVWDMAASVPKTKFYYSPLCWWPLLCPSGTSATDIRGANASFAMDLSARNDGLLNATVRDMMIELGEINVTVAVRGMQLLNNLINGIIDIFKGSIKNELQRIVPGIINPVVQSKAEEIFRGFPIIYMKDPNITEQRAELLMGIFSDESSSRVVSQDEVLAVDQSLPYRSVSITSSYRAANNVLRLLNNWSMLNVSLLLPERYNSSLIEPMYPELFRLCRGCNFGVSAVLPSPPWLETVSGGAFIFNSRNGNFTLEMVSEDNVSFTVLNMVVNLTANVRHMSIDNNTLDLKLSSMDVVTELGTSLIDGLNSTTLNTDIRRFLDEVGLPLFNADPHGFRLPFNISGLLLSVSNATITVGLDPKPIFPLLNKFVDRLM
Protein: Distal membrane-arm assembly complex protein 2 (ATP synthase subunit s-like protein) (Q9NW81)
Organism: Homo sapiens (Human)
Function: Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9D7K5}.
Interaction partners:
- FAD-dependent oxidoreductase domain-containing protein 1
- Transmembrane protein 70
- Distal membrane-arm assembly complex protein 1
- Transmembrane protein 186
Sequence:
MAAPWASLRLVAPMWNGRIRGIHRLGAAVAPEGNQKKKRTILQFLTNYFYDVEALRDYLLQREMYKVHEKNRSYTWLEKQHGPYGAGAFFILKQGGAVKFRDKEWIRPDKYGHFSQEFWNFCEVPVEAVDAGDCDINYEGLDNLLRLKELQSLSLQRCCHVDDWCLSRLYPLADSLQELSLAGCPRISERGLACLHHLQNLRRLDISDLPAVSNPGLTQILVEEMLPNCEVVGVDWAEGLKSGPEEQPRDTASPVPA
Protein: Uricase (EC 1.7.3.3) (Urate oxidase) (P16163)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
Subcellular location: Peroxisome {ECO:0000269|PubMed:2118989}.
Interaction partners:
- 5-hydroxyisourate hydrolase
- Xanthine dehydrogenase
- Aldehyde oxidase 1
- allantoinase
- Aldehyde oxidase 3, isoform A)
- Aldehyde oxidase 2
- Aldehyde oxidase 4
- LD30822p
- Alanine--glyoxylate aminotransferase
- Beta-ureidopropionase
Sequence:
MFATPLRQPAAANHQTPKNSAGMDEHGKPYQYEITDHGYGKDAVKVLHVSRNGPVHAIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKNTVYLLAKKHGIESPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQEETRTNVNGKCENGVQGNCDFSSIDNRSLHNHAFIFTPTALHYCDVVIRRTDPKQTVITGIKGLRVLKTTQSSFVNFVNDEFRSLPDQYDRIFSTVVDCSWEYSDTENLDFLRAWQTVKNIIIRNFAGDPQVGVSSPSVQHTLYLSERQVLDVLPQVSVISMTMPNKHYFNFDTKPFQKIAPGDNNEVFIPVDKPHGTIYAQLARKNINSHL
Protein: Mitogen-activated protein kinase kinase kinase YODA (EC 2.7.11.25) (YODA MAPKK kinase) (Q9CAD5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions in a MAP kinase cascade that acts as a molecular switch to regulate the first cell fate decisions in the zygote and the early embryo. Promotes elongation of the zygote and development of its basal daughter cell into the extra-embryonic suspensor. In stomatal development, acts downstream of the LRR receptor TMM, but upstream of the MKK4/MKK5-MPK3/MPK6 module to regulate stomatal cell fate before the guard mother cell (GMC) is specified. Plays a central role in both guard cell identity and pattern formation. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the morphology of plant organs. Upon brassinosteroid signaling, is inhibited by phosphorylation of its auto-inhibitory N-terminal domain by the GSK3-like kinase ASK7.
Subcellular location: Cytoplasm, cell cortex {ECO:0000269|PubMed:25843888}. Cell membrane {ECO:0000269|PubMed:25843888}. Note=Recruited by BASL at the cell cortex in a polarized manner. {ECO:0000269|PubMed:25843888}.
Interaction partners:
- Mitogen-activated protein kinase kinase 4
- Mitogen-activated protein kinase kinase 5
- LRR receptor-like serine/threonine-protein kinase ERL2
- LRR receptor-like serine/threonine-protein kinase ERL1
- Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE
- Transcription factor SPEECHLESS
- LRR receptor-like serine/threonine-protein kinase ERECTA
- Protein EPIDERMAL PATTERNING FACTOR 1
- Transcription factor MUTE
- WUSCHEL-related homeobox 8
Sequence:
MPWWSKSKDEKKKTNKESIIDAFNRKLGFASEDRSSGRSRKSRRRRDEIVSERGAISRLPSRSPSPSTRVSRCQSFAERSPAVPLPRPIVRPHVTSTDSGMNGSQRPGLDANLKPSWLPLPKPHGATSIPDNTGAEPDFATASVSSGSSVGDIPSDSLLSPLASDCENGNRTPVNISSRDQSMHSNKNSAEMFKPVPNKNRILSASPRRRPLGTHVKNLQIPQRDLVLCSAPDSLLSSPSRSPMRSFIPDQVSNHGLLISKPYSDVSLLGSGQCSSPGSGYNSGNNSIGGDMATQLFWPQSRCSPECSPVPSPRMTSPGPSSRIQSGAVTPLHPRAGGSTTGSPTRRLDDNRQQSHRLPLPPLLISNTCPFSPTYSAATSPSVPRSPARAEATVSPGSRWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGRVKVADFGMAKHITAQSGPLSFKGSPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMATTKPPWSQYEGVPAMFKIGNSKELPDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFVRNVMPMERPIVSGEPAEAMNVASSTMRSLDIGHARSLPCLDSEDATNYQQKGLKHGSGFSISQSPRNMSCPISPVGSPIFHSHSPHISGRRSPSPISSPHALSGSSTPLTGCGGAIPFHHQRQTTVNFLHEGIGSSRSPGSGGNFYTNSFFQEPSRQQDRSRSSPRTPPHVFWDNNGSIQPGYNWNKDNQPVLSDHVSQQLLSEHLKLKSLDLRPGFSTPGSTNRGP
Protein: 5-hydroxytryptamine receptor 5A (5-HT-5) (5-HT-5A) (5-HT5A) (Serotonin receptor 5A) (P30966)
Organism: Mus musculus (Mouse)
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P47898}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Guanine nucleotide-binding protein G
- 5-hydroxytryptamine receptor 5B
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-4
- Basigin
- Guanine nucleotide-binding protein G
Sequence:
MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLLVLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFGWGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVSPVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
Protein: Cytochrome c oxidase subunit 2 (Q69GF7)
Organism: Sus scrofa (Pig)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000457}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU000457}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004225}.
Interaction partners:
Sequence:
MAYPFQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPALTVKTMGHQWYWSYEYTDYEDLTFDSYMIPTSDLKPGEMRLLEVDNRVVLPMEMTIRMLVSSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEKWSTSMLTG
Protein: Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 7.2.2.10) (Ca(2+)/Mn(2+)-ATPase 2C2) (Secretory pathway Ca(2+)-transporting ATPase type 2) (SPCA2) (A7L9Z8)
Organism: Mus musculus (Mouse)
Function: ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway. Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side. The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state (By similarity). Induces Ca(2+) influx independently of its ATP-driven pump function. At the basolateral membrane of mammary epithelial cells, interacts with Ca(2+) channel ORAI1 and mediates Ca(2+) entry independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. May facilitate transepithelial transport of large quantities of Ca(2+) for milk secretion via activation of Ca(2+) influx channels at the plasma membrane and active Ca(2+) transport at the Golgi apparatus (By similarity).
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15677451}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O75185}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:23840669}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- C-Maf-inducing protein
Sequence:
MGRRLKFLQKLAFLGQNHRYKALERDEVETLIDEQCELKAIEREKTVAALPPGEACKCSREELARAFHVDLDSGLSEFAVAQRRLVHGWNEFVTDNAEPVWKKYLDQFRNPLILLLLGSSVVSVLTKEYEDAVSIALAVLIVVTVGFIQEYRSEKSLEELTKLVPPECNCLRDGKLRHMLARDLVPGDIVSLSMGDRIPADIRLTEVTDLLVDESSFTGEVEPCGKTDSPLADGGDLSTLSNVVFMGTLVQCGKGQGVVIGTGEQSQFGEVFKMMRAEETPKTPLQKSMDKLGKQLTIFSFGIIGLLMLVGWVQGKPFLSMFTVGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTATQLVTSDGFHAEVSGVGYSGEGTVCLLPSKEVIKGFDNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALVVLAMKMNLGSIKDSYVRKKEIPFSSEQKWMAVRCGPKSEDGEDIYFMKGAFEEVIHHCSMYNNGGIPLPLTPQQKSYCQQEEKKMGSLGLRVLALASGPELGRLTFLGLVGIIDPPRAGVKEAVQVLSESGVSVKMVTGDALETALAIGRTIGLCNEKLKAMSGEEVEGTEQGALAARVRQVSVFFRTSPKHKVKIIKALQESGAIVAMTGDGVNDSVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMSAVEEGKGIFYNIKNFVRFQLSTSIAALSLITLSTVCNLPSPLNAMQILWVNIIMDGPPAQSLGVEPVDRDALRRPPRSVGDTILNRALILRVLMSAAVIIGGTLFIFWREIPANGTSTPRTTTMAFTCFVFFDLFNALSCRSQTKLIFEIGFFRNRMFLYSVLGSLLGQLAVIYAPPLQKVFQTENLSALDLLLLTGLASSVFILSELLKLWEKFLSRARPTQMLPEAV
Protein: Uncharacterized protein (Q383W9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWRRGVAAVPLPLWQGKLLQLVHHRALSTDTTGDEATAWSRAMEAKYGTGTYKLFRPLYKDLSDEMRLEAYTKPPAPMQGWSVHHDEAVNLAIFSHKGDSRSRTARVVAYSPITVENPESLNPLLYFMDWYPINVLMERNGVVVHFSIASTEGGMHMRNVRVYKAQDELSPNDPEKQDLPNRDSECERLMSTTDDAAWVRHNLYYDGPCLWHLELDMLNELYDVMQDHGVTLDWVRWVAEWVHYLEHVSYVRWALGVLQELIPVDERGPEDDFLTFEEKEALATPPEEWLEAHYI
Protein: protein-tyrosine-phosphatase (EC 3.1.3.48) (F1MAG7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Mast/stem cell growth factor receptor
Sequence:
MVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLFSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDHKGYIGLDDILLFSHPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLLSRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYHYTLGGSHNQTIRECVKMERGASRYTIKNLLPFRNVHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLQPGTTYLFSVRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVVVEEERPRRLRREPGGQDCFSVPLTFETALARGLVHYFGAELAASSLLEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIIIIRKGRDRYAYSYYPKPVNMAKATVNYRQEKTHMMTAVDRSFTDQSTLQEDERLGLSFMDAPGYSPRGDQRSSGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKLKSGRQEPVSAYDRHRVKLHPMLGDPDADYISANYIDIRINRQGYHRSNHFIATQGPKPEMIYDFWRMVWQEQCVSVVMISKLVEVGRVKCSRYWPEDSDMYGDIKITLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPVVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFVSGTANEDLVSRVFRVQNSSRLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVVHCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEALELR
Protein: Homocysteine synthase (EC 2.5.1.49) (O-acetylhomoserine sulfhydrylase) (OAH SHL) (OAH sulfhydrylase) (P50125)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway. Has also cysteine synthase (O-acetylserine sulfhydrylase) activity in vitro, but seems only be involved in the alternative pathway of methionine biosynthesis in E.nidulans.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P06106}.
Interaction partners:
- Cysteine synthase 1
- Cystathionine beta-synthase
- Cysteine synthase 2
- cystathionine gamma-synthase
- 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
- assimilatory sulfite reductase
- Sulfite reductase subunit beta
- Homocysteine S-methyltransferase
- Cystathionine beta-lyase
- cystathionine gamma-lyase
Sequence:
MSDPSPKRFETLQLHAGQEPDPATNSRAVPIYATTSYTFNDSAHGARLFGLKEFGNIYSRIMNPTVDVFEKRIAALEGGVAAVAASSGQAAQFMAISALAHAGDNIVSTSNLYGGTYNQFKVLFPRLGITTKFVQGDKAEDIAAAIDDRTKAVYVETIGNPRYNVPDFEVIAKVAHEKGIPLVVDNTFGAGGYFVRPIEHGADIVVHSATKWIGGHGTTIGGVVVDSGKFDWGKNAARFPQFTQPSEGYHGLNFWETFGPIAFAIRVRVEILRDLGSALNPFAAQQLILGLETLSLRAERHASNALALANWLKKNDHVSWVSYVGLEEHSSHEVAKKYLKRGFGGVLSFGVKGEAAVGSQVVDNFKLISNLANVGDSKTLAIHPWSTTHEQLTDQERIDSGVTEDAIRISVGTEHIDDIIADFEQSFAATFKVVRSA
Protein: Small ribosomal subunit protein bS16c (30S ribosomal protein S16, chloroplastic) (Q6ENJ5)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Uncharacterized protein
- Small ribosomal subunit protein uS12c
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS10 domain-containing protein
- Small ribosomal subunit protein uS10 domain-containing protein
- 30S ribosomal protein S9
- Small ribosomal subunit protein uS9c
- 50S ribosomal protein L31
- Large ribosomal subunit protein bL27c
- S5 DRBM domain-containing protein
Sequence:
MLKLRLKRCGRKQRAVYRIVAIDVRSRREGRDLRKVGFYDPIKNQTCLNVPAILYFLEKGAQPTRTVSDILRKAEFFKEKERTLS
Protein: Small GTPase, putative (Q385W0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- VPS9 domain-containing protein
- Rab GDP dissociation inhibitor
- Vacuolar protein sorting-associated protein 45, putative
- Geranylgeranyl transferase type-2 subunit alpha
- RING-type domain-containing protein
- Ras-related protein Rab-7b
- Pep3/Vps18/deep orange beta-propeller domain-containing protein
- Vacuolar protein sorting complex subunit, putative
- RING-type domain-containing protein
- Vacuolar protein sorting 33, putative
Sequence:
MSVKTLAAPTKKYKIVLLGDSGVGKSSLVQRLAKNEWCDNQNSTVGASFLRYVCTVGDTAVNFDIWDTAGQERYKSLASMYYRGAAAALVVYEIPSWETFERAKHWVRELATNSPETIVILVGNKSDLRGTSGCVSSEEAATYARELNLLFSEASAKDGSGVSEVFMQIAQRLVASNNNNTVHSGGVLGGQPNSTRRSSGCCG
Protein: Epidermal growth factor receptor pathway substrate clone 15, isoform A (Q9W111)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- FI19443p1
- AP-2 complex subunit alpha
- Dynamin associated protein 160, isoform D
- AT02057p
- Protein stoned-B
- Clathrin heavy chain
- Epidermal growth factor receptor
- Protein numb
- AP complex subunit beta
- Clathrin light chain
Sequence:
MNVDFARVCGKHIGVYEAYYKLIDPKGTGAIEAMTAAKFLKKSGLSDVVLSRIWDLSDPSGKGFLDKPGFFVALKLVSLSQAGQVASMANIYLDIANPPKLGELPKTMPSRIQTVPVASGGVANGDWSIGVIDRLKYEQLFESLHPSNGMLPGNKVKGVLMDSKLPMSILGTIWDLADQDKDGNLDMHEFVVAMHLVYQTLQKRTIPSVLPPELRKPGGAGPPPKPAMPPPPAGAAMPRAPSGEGFGDGGFVANFPKDIAPPAAIPPLPVAVPPMTRIPPVGAVSSQPLIQTDPLIPIGAPVMANADWVVTPADLKRFEEIFRQSDLDKDGLVSGLEVKDIFIKSGIPQRSLADIWALCDTNQSGKLTVEQFALAMWFVERKQRGVDPPHVLNANMVPPSMRATVAGVDLQPQEVKPTYSNPELEMISKEIEELARERRVLETEIAQKEADVRIKNGEVRSLQSELDTLTATLKQLENQRGEAQKRLDDLQAQVSHNTAVLANVSLDISRTNEQVTKIRDQCHMQEVTINEQEGELNAKRSELQKLKDEEASLQKEYDSNNRELSKLTNHLQATQLQISSVRSMVTQLLETQRQMTDALLICRAAMENQNAELVSEYQLKIEPDFDEARKTLTKEVQLPKDDPFEENNSGAANQATNGFGSDPFSGQPVNKPAISTGFDDSFNMSSGFDSGFDAFGQSGAGSAFGQTQRDPFGSDAFAANKSNAITPEPGKDDFGSDPFAALHAPTGQGQVLSPNAQKSGPPPRPESPSPALPPKKSKVPPPRPAPPRAAQPTGGFGSGGGGGFADFDDFDNKLHHIPSAPSPSATALSPLPPTLPAPIPVVSGSSLLDSFTLFDDPGQIHKQAASTPNPTPITVPTVHTLLQTSLSTPAAPSPALASLSTSGSGSVAGAGADLPSSVTITTAPSLNNQHLSRSNTPLQNQRTADVKLETKAVVSVFDAFGEIGTRKAPTPSLITGPTDFKDDPFKDYRYEDPFSIKDPFAEEGEEELSEGKGADHKRNFAEDFSSGDEIGSAAKTLSNIVNNNSIKPKAATPLNNDLLQQFDAFNLNSSPAPSHHSGTSYHSNSKPSHDSQTALDAFADFDDFAATLATTGGSGAATTATTTGNTKLNNSFFDAFNDNFSVIQSSSVPTGVVRPNDQRAKAFDAFNDNFEDQFKTSPNANFAKFDGFEAHNFSSDFGNASFGTTGKEKQNGQVDKKFQSKEPVKDKFAADYSKPESFDADLEEALKRSVLDN
Protein: Transthyretin (xTTR) (Prealbumin) (B7ZS96)
Organism: Xenopus laevis (African clawed frog)
Function: Thyroid hormone-binding protein, with a much higher binding affinity for triiodothyronine (T3) than for thyroxine (T4). Probably transports triiodothyronine from the bloodstream to the brain.
Subcellular location: Secreted {ECO:0000269|PubMed:11080066}.
Interaction partners:
Sequence:
MASFKSFLLLALLAIVSEAAPPGHASHGEADSKCPLMVKVLDAVRGIPAANLLVNVFRQTESGKWEQITSGKTTELGEIHNLTTDEQFTEGVYKIEFATKAFWGKLGLSPFHEYVDVVFTANDAGHRHYTIAVLLTPYSFSSTAIVSEPHDDL
Protein: Leucine rich repeat containing 4C, genome duplicate a isoform X1 (Leucine rich repeat containing 4C, genome duplicate a precursor) (Leucine-rich repeat-containing 4C, genome duplicate a) (Zgc:110565) (Q503I7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Netrin-G1
- Netrin g1a.
- Leucine-rich repeat-containing 4C, genome duplicate b
- Pleckstrin homology domain-containing, family H
- Pleckstrin homology domain-containing family F member 2
- E3 ubiquitin-protein ligase NEURL1B
- Family with sequence similarity 43 member A
Sequence:
MINKMTSSLMQQTMRGPRWNRALSDPLFVLSLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICTRRGLRDVPDGISTNTRYLNLQENLIQVIKVDSFKHLRHLEILQLSKNHIRNIEIGAFNGLANLNTLELFDNRLTTIPNGAFEYLSKLKELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLGMCNLKEIPNLIPLVRLDELEMSGNQLSIIRPGSFKGLVHLQKLWMMHAQIQTIERNAFDDLQSLVELNLAHNNLTLLPHDLFTPLHHLERVHLHHNPWNCNCDILWLSWWLKEMVPANTSCCARCSSPTSHKGRYIGELDQNYFHCYAPVIVEPPADLNVTEGMAAELKCRANSLTSVSWITPNGSIMTHGAYKIRISVLNDGTLNFTNVTMQDTGTYTCMVSNSAGNTTASATLNVSSTENSSFSYFTTVTVETTEAPPDEGHPTVQQKNGPTPSSGIWETLPPSFTTTTTTARTPLSTKATDKTYTIPVTAQSDGSLNTLDEVMKTTKIIIGCFVAITLMAAVMLIIFYKMRKQHHQQNHHAPTRAIEIINVDEDCMTGGPAMESHLALPPLDHEHLNHYNAYKTAYNHASTINSIHSSAHEPLLIRASSKDNVQETQI
Protein: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.3.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (ST6GalNAcI) (Sialyltransferase 7A) (SIAT7-A) (Q92183)
Organism: Gallus gallus (Chicken)
Function: Protein sialyltransferase specifically expressed in goblet cells that plays a key role in intestinal host-commensal homeostasis (By similarity). Conjugates sialic acid with an alpha-2-6 linkage to N-acetylgalactosamine (GalNAc) glycan chains linked to serine or threonine in glycoproteins.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9NSC7}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9NSC7}.
Interaction partners:
- Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
- Glucosaminyl
- Polypeptide N-acetylgalactosaminyltransferase
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
- C1GALT1 specific chaperone 1
- Polypeptide N-acetylgalactosaminyltransferase.
- Polypeptide N-acetylgalactosaminyltransferase
- Glyco_trans_2-like domain-containing protein.
- Polypeptide N-acetylgalactosaminyltransferase
- Polypeptide N-acetylgalactosaminyltransferase.
Sequence:
MGFLIRRLPKDSRIFRWLLILTVFSFIITSFSALFGMEKSIFRQLKIYQSIAHMLQVDTQDQQGSNYSANGRISKVGLERDIAWLELNTAVSTPSGEGKEEQKKTVKPVAKVEEAKEKVTVKPFPEVMGITNTTASTASVVERTKEKTTARPVPGVGEADGKRTTIALPSMKEDKEKATVKPSFGMKVAHANSTSKDKPKAEEPPASVKAIRPVTQAATVTEKKKLRAADFKTEPQWDFDDEYILDSSSPVSTCSESVRAKAAKSDWLRDLFLPNITLFIDKSYFNVSEWDRLEHFAPPYGFMELNYSLVEEVMSRLPPNPHQQLLLANSSSNVSTCISCAVVGNGGILNNSGMGQEIDSHDYVFRVSGAVIKGYEKDVGTKTSFYGFTAYSLVSSLQNLGHKGFKKIPQGKHIRYIHFLEAVRDYEWLKALLLDKDIRKGFLNYYGRRPRERFDEDFTMNKYLVAHPDFLRYLKNRFLKSKNLQKPYWRLYRPTTGALLLLTALHLCDRVSAYGYITEGHQKYSDHYYDKEWKRLVFYVNHDFNLEKQVWKRLHDENIMKLYQRS
Protein: Carbonyl reductase (NADPH) (EC 1.1.1.184) (V9HW40)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369024}.
Interaction partners:
Sequence:
MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW
Protein: Patatin-like protein, PlpD (Q9HYQ6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Translocation/assembly module TamB
- Outer membrane protein assembly factor BamA
- Probable hemagglutinin
Sequence:
MRRLLLVLLLLLPLSALAAEARPKIGLVLSGGAARGLAHIGVLKALDEQGIQIDAIAGTSMGAVVGGLYASGYTPAELERIALEMDWQQALSDAPPRKDVPFRRKQDDRDFLVKQKISFRDDGTLGLPLGVIQGQNLAMVLESLLVHTSDNRDFDKLAIPFRAVSTDIATGEKVVFRKGHLPQAIRASMSIPAVFAPVEIDGRLLVDGGMVDNIPVDVARDMGVDVVIVVDIGNPLRDRKDLSTVLDVMNQSITLMTRKNSEAQLATLKPGDVLIQPPLSGYGTTDFGRVPQLIDAGYRATTVLAARLAELRKPKDLNSEALDVARTPNQRKPVIDAIRVENNSKVSDEVIRHYIRQPLGTRLDLGRLQDDMSTLYGLDYFDQVQYRVVKEKKLNTLVIHATGKKGGTDFLRLGLNLSDDMRGESTFNLGGSYRMNGLNRLGAEWLTRVQLGDRQELYSEFYQPLDVGSRYFVAPFLFHEAQNVDVTEDNDPLLRYRLERYGYGLNVGRQIANNGEIRLGAVQAYGKADVRIGDPSLPDIDFTEGYYELKYSFDTVDDVNFPHEGEEIGLTMRRYDKSLGSDDSYRQWDLRLNKALSFGADTWVFGGGYGRTLDDAEVVTSSFTLGGARELSGFRRDALSGQNYSLGRIVYYRRLTERSFLPLDFPLYLGGSIERGRIWNNDNEYDSGYINAASLMIGFDTPLGPLTFSYGINDENFKAFYLNLGQNF
Protein: Uncharacterized WD repeat-containing protein YNL035C (P53962)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- FAS1 domain-containing protein YDR262W
Sequence:
MASYSLVESNSFGSENWCLKLQPSYKHGLLTGLSNGEIRLLDWSTGKSVQKIKASETAINDMKVIGSDFSAGHLVSSASIDAVKVFDIRTNDRIAQIQNEANSPFISLDSRHGLLACGTELQGIDAAVYIYDIRKWDTPLRSLIDSHHDDVTCIKFHPSDVNILLSGSTDGYTNIYDLKQDEEEDALHQVINYASIHSCGWLSPKRIFTLSHMETFAIHELNDKSDELKEPQPLDFGDVREIWNCDYVVDIYPGLIATGKTQENCGELCLLPFKDEKVDTENGIVIPHAHGDEVVRDIFIPAQHSNMLYSCGEDGCVKIWENKQGPLDIPENFWDYSKKMNVLGDDDREGSINLDEPLIIQKESVSTRPRKEKHKKAKKHSMKSRFKPY
Protein: D-tagatose-1,6-bisphosphate aldolase subunit GatY (TBPA) (TagBP aldolase) (EC 4.1.2.40) (D-tagatose-bisphosphate aldolase class II) (Tagatose-bisphosphate aldolase) (P0C8J6)
Organism: Escherichia coli (strain K12)
Function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol. Has a high aldolase activity for TBP and a very low one for fructose 1,6-bisphosphate (FBP).
Interaction partners:
- D-tagatose-1,6-bisphosphate aldolase subunit GatZ
- PTS system galactitol-specific EIIA component
- D-tagatose-1,6-bisphosphate aldolase subunit KbaZ
- ATP-dependent 6-phosphofructokinase isozyme 1
- PTS system galactitol-specific EIIB component
- ATP-dependent 6-phosphofructokinase isozyme 2
- L-threonate dehydrogenase
- 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
- D-tagatose-1,6-bisphosphate aldolase subunit KbaY
- Galactitol 1-phosphate 5-dehydrogenase
Sequence:
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
Protein: Type II secretion system protein K (E0SLF7)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004533, ECO:0000256|PIRNR:PIRNR002786}.
Interaction partners:
- Type II secretion system protein J
- Type II secretion system protein I
- Type II secretion system core protein G
- Type II secretion system protein H
- Type II secretion system protein L
- Type II secretion system protein C
- Type II secretion system protein M
- Secretin OutD
- Type II secretion system protein J
- General secretion pathway protein K
Sequence:
MSRRQRGVALLIVMLMLSLMVTIAASITERSGKAWQRTSNLLNRTQARWYALGAEALISSVLQRDAQASPESTFIGQPWSKVDHQMMADGSEIRAQVLDGQACLNLNALSPAKKPAPGNNNTSGNAGNSNTDTNNQSPPAKGGNPEQGPYAAQVFRQLLMVLGEDPKQAERVTDAVRDWIDEDSEPLMNGAEDDSYVNFHPGNQRMTDVTELRAVMGVDAALYRRLLPYVCVLPVDKLVINVNTLTPESAPLLSALFMGEMSAEAAERVLQQRPPQGWRNLNDFMGLSALPENAKTGVRQVLAIKSDWFFADIQIRVDDSEFYQRSLFHRGKQIEVVQRQYGGYRTVNP