wanglab/gogpt-training-data huggingface dataset:
Protein: Membrane progestin receptor gamma (mPR gamma) (Membrane progesterone P4 receptor gamma) (Membrane progesterone receptor gamma) (Progesterone and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member V) (Q9NXK6)
Organism: Homo sapiens (Human)
Function: Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation.
Subcellular location: Cell membrane {ECO:0000303|PubMed:23763432}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Membrane-associated progesterone receptor component 2
- Membrane-associated progesterone receptor component 1
- Kinesin-like protein KIF23
Sequence:
MLSLKLPRLFSIDQIPQVFHEQGILFGYRHPQSSATACILSLFQMTNETLNIWTHLLPFWFFAWRFVTALYMTDIKNDSYSWPMLVYMCTSCVYPLVSSCAHTFSSMSKNARHICYFLDYGAVNLFSLGSAIAYSAYTFPDALMCTTFHDYYVALAVLNTILSTGLSCYSRFLEIQKPRLCKVIRVLAFAYPYTWDSLPIFYRLFLFPGESAQNEATSYHQKHMIMTLLASFLYSAHLPERLAPGRFDYIGHSHQLFHVCVILATHMQMEAILLDKTLRKEWLLATSKPFSFSQIAGAILLCIIFSLSNIIYFSAALYRIPKPELHKKET
Protein: Beta-lactamase (EC 3.5.2.6) (O24823)
Organism: Serratia marcescens
Interaction partners:
Sequence:
MTKMNRLAAALIAALILPTAQAAQQQDIDAVIQPLMKKYGVPGMAIAVSVDGKQQIYPYGVASKQTGKPITEQTLFEVGSLSKTFTATLAVYAQQQGKLSFNDPASRYLPELRGSAFDGVSLLNLATHTSGLPLFVPDDVTNDAQLMAYYRAWQPKHPAGSYRVYSNLGIVMLGMIAAKSLDQPFIQAMEQGMLPALGMSHTYVQVPAAQMANYAQGYSKDDKPVRVNPGPLDAKSYGIKSNARDLIRYLDANLQQVKVAHAWRDALAATHVGYYKAGAFTQDLMWENYPYPVKLSRLIEGNNAGMIMNGTPATAITPPQPELRAGWYNKTGSTGGFSTYAVFIPAKNIAVVMLANKWFPNDDRVEAAYHIVQALEKR
Protein: Guanylate-binding protein 10 (Q000W5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGWSRTGKSYLMNCLAGQNHGFPLGSTVQSQTKGIWMWCMPHPTKPEHTLVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFIYNSMITINHQALEQLHYVTELTELIRAKSSPNPAGIKNSTEFVSFFPDFVWIVRDFMLELKLNGEDITSDDYLENALKLIPGDKPRMQASNSCRECIRLFFPNRKCFVFDRPTHDKELLQKLDSITEDQLDPKFQEVTKAFVSYIFTYAKIKTLKEGIKVTGNKLGILVTTYVDAINSGAVPCLDDAVTTLAQRENSVAVQKAADHYSEQMAQRLRLPTETLQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELIGENKELFLSKNEEASNKYCQEELDRLSKDFMENISTFFVPCGHKLYMDKREKIEHDYWQVPRKGVKASEVFQSFLQSQAFIESSILQADTALTAGKKAIAEERAQKVAAEKEQDLLRQKQKEQQEYMEAQEKSHKENIEQLRRKLMQEREQLIKDHNMMLKKQLKDQKAFLEEGFKKKAEEMNKEIQQLRDVIKDKKRNTDRIKDALLNGFSTVLFHYLVRYLKHL
Protein: Zinc finger protein 558 (Q96NG5)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MAAVILPSTAAPSSLFPASQQKGHTQGGELVNELLTSWLRGLVTFEDVAVEFTQEEWALLDPAQRTLYRDVMLENCRNLASLGCRVNKPSLISQLEQDKKVVTEERGILPSTCPDLETLLKAKWLTPKKNVFRKEQSKGVKTERSHRGVKLNECNQCFKVFSTKSNLTQHKRIHTGEKPYDCSQCGKSFSSRSYLTIHKRIHNGEKPYECNHCGKAFSDPSSLRLHLRIHTGEKPYECNQCFHVFRTSCNLKSHKRIHTGENHHECNQCGKAFSTRSSLTGHNSIHTGEKPYECHDCGKTFRKSSYLTQHVRTHTGEKPYECNECGKSFSSSFSLTVHKRIHTGEKPYECSDCGKAFNNLSAVKKHLRTHTGEKPYECNHCGKSFTSNSYLSVHKRIHNRWI
Protein: 65-kDa microtubule-associated protein 1 (AtMAP65-1) (Q9FLP0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Microtubule-associated protein that bundle and stabilize adjacent microtubules (MT) of the cell cortex. Enhances MT nucleation. Can also bind to tubulin dimers and promotes their polymerization. Confers MT resistance to the drug propyzamide and cold conditions. Plays a role in the central spindle at anaphase to early cytokinesis but is not essential at the midline of the phragmoplast at later stages. Represses metaphase spindle organization and the transition to anaphase in dephosphorylated active form. Promotes the formation of a planar network of antiparallel microtubules. May be involved in stomatal movement modulation by regulating the dynamic and arrangement of cortical MT.
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cell cortex. Note=During interphase, binds cortical microtubules. In M-phase, locates to the preprophase band. Binds the preprophase band but does not accumulate at the prophase spindle microtubules that coexists within the same cell. In the metaphase and anaphase, localized to spindle. In the phragmoplast, concentrated at the midzone where vesicles guide by MT coalesce to form the cell plate. Present in MT cortical arrays. Concentrated in dots surrounding the nuclei.
Interaction partners:
- At4g28310
- Kinesin-like protein KIN-7A
- Microtubule-associated protein RP/EB family member 1A
- Microtubule-associated protein 70-1
- Phospholipase D alpha 1
- Amidophosphoribosyltransferase 1, chloroplastic
- CLIP-associated protein
- Microtubule-associated protein RP/EB family member 1B
- Mitogen-activated protein kinase 4
- Katanin p60 ATPase-containing subunit A1
Sequence:
MAVTDTESPHLGEITCGTLLEKLQEIWDEVGESDDERDKLLLQIEQECLDVYKRKVEQAAKSRAELLQTLSDANAELSSLTMSLGDKSLVGIPDKSSGTIKEQLAAIAPALEQLWQQKEERVREFSDVQSQIQKICGDIAGGLSNEVPIVDESDLSLKKLDDFQSQLQELQKEKSDRLRKVLEFVSTVHDLCAVLGLDFLSTVTEVHPSLDEDTSVQSKSISNETLSRLAKTVLTLKDDKKQRLQKLQELATQLIDLWNLMDTPDEERELFDHVTCNISSSVDEVTVPGALARDLIEQAEVEVDRLDQLKASRMKEIAFKKQSELEEIYARAHVEVNPESARERIMSLIDSGNVEPTELLADMDSQISKAKEEAFSRKDILDRVEKWMSACEEESWLEDYNRDQNRYSASRGAHLNLKRAEKARILVSKIPAMVDTLVAKTRAWEEEHSMSFAYDGVPLLAMLDEYGMLRQEREEEKRRLREQKKVQEQPHVEQESAFSTRPSPARPVSAKKTVGPRANNGGANGTHNRRLSLNANQNGSRSTAKEAGRRETLNRPAAPTNYVAISKEEAASSPVSGAADHQVPASP
Protein: ATP synthase protein I (P0ABC0)
Organism: Escherichia coli (strain K12)
Function: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- ATP synthase subunit a
- ATP synthase subunit c
- ATP synthase subunit delta
- ATP synthase subunit b
- ATP synthase subunit alpha
- ATP synthase gamma chain
- ATP synthase epsilon chain
- ATP synthase subunit beta
- Prophage lysis protein S homolog EssQ
Sequence:
MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGGLAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFLPLIVTWVLVLVVQILAPAVINNKG
Protein: Serotonin N-acetyltransferase (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (F1T0I5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC
Protein: Microsomal glutathione S-transferase 2 (Microsomal GST-2) (Microsomal GST-II) (EC 1.11.1.-) (EC 2.5.1.18) (EC 4.4.1.20) (Glutathione peroxidase MGST2) (Leukotriene C4 synthase MGST2) (Microsomal glutathione S-transferase II) (A0A0G2JU12)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU369123}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU369123}. Microsome membrane {ECO:0000256|RuleBase:RU369123}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU369123}.
Interaction partners:
- Microsomal glutathione S-transferase 1
- Glutathione S-transferase 3, mitochondrial
- Glutathione S-transferase omega-1
- glutathione transferase
- Hematopoietic prostaglandin D synthase
- Glutathione S-transferase alpha-3
- Glutathione S-transferase
- Glutathione S-transferase Mu 5
- Glutathione S-transferase Mu 7
- Glutathione S-transferase kappa 1
Sequence:
MAGDSSLLAAVSLLSACQQSYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFYSVFIISLWMAGWYFNQEFPMMDLNEADCLEEKVLGFCNLSGSPVHIRPSQVFLGLCRSR
Protein: Eukaryotic translation initiation factor 5B (Translation initiation factor IF-2) (Q8N5A0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNTVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQIRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLKDELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMKASVMLEHDPQYAVNLAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQKQEEFKHIAVFPCKIKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTSIEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRDEMQKSDWQLIVELKKVFEII
Protein: Carbamoyl-phosphate synthase/carboxyl transferase (Q9A3J0)
Organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus)
Interaction partners:
- Urea amidolyase-related protein
- propionyl-CoA carboxylase
- Acetyl/propionyl-CoA carboxylase, alpha subunit
- biotin--[biotin carboxyl-carrier protein] ligase
- Malate dehydrogenase
- 4-hydroxyphenylpyruvate dioxygenase
- Biotin carboxyl carrier protein of acetyl-CoA carboxylase
- Fatty oxidation complex, alpha subunit
- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- 3-hydroxy-3-methylglutarate-CoA lyase
Sequence:
MSLSRVLIANRGEIAVRIARTAAEAGLESVAIYAADDAQSPHVSAADHAVALPGAGARAYLDIAAVVAAAKAQGCDALHPGYGFLSENPHLARACAEAGIVFIGPSPEHLTTFGDKAAARALAAERGLPLIPGTGAITLEAARAFQAEHGAIMLKARAGGGGRGMRMVLDPGELDAAFAACEREALAAFGDGGLYAEKLIERARHIEVQIVGDGDQVLALGDRDCSLQRRNQKLVEIAPAALPDNLRAALAGWSERLCAGYRGLATVEFLVDADPHSPSGGEAFFIEVNPRLQVEHTVTEEVTGLDLVRLQFDLAAGKRLGELELTNTPPPFGVAIQARINAETLTPEGQVRPSTGTLSAWTPPGGPGVRVDAGVAAGLTIGAAYDSLLAKVIVRGRTPSEAASRLDRALTELKVAGVATTAPLVRAILAHPTAVTGEATTTFIAQHAETLAAEAQRLTPETTASVTRFEVLAGAEPVVAPLAATVGAITIREGDLVRPGQALAVLEAMKMEHLVSASAGGRVVKIVVQGGATVAEGQPLVFLEPAEVESALDGETVEQDLDALRPDLAEVVARHRHTLDEARPEAVAKRRKTGHRTARENIDDLVDPGSFLEYGALAIAAQKRRRSTEDLIANTPADGLITGIGTVNGALFPPDKARTAALAYDFTVLAGTQGAMNHRKSDRLMALIADQKLPVVWFAEGGGGRPGDTDTTAVAGLDVPTFRSFAQLSGLVPKIAIVAGRCFAGNAAIAGLSEIIIATRDSNLGMGGPAMIEGGGLGVFRPEEIGPSAHQWKNGVIDILADDEAHATRLAKQALSYFQGTLSTWTAPDQRRLRHAIPENRLRVYDVRGLINHLVDEGSFLELRGGFAAGMVTGLIRIEGRPMGLIANDPRHLGGAIDCEGAEKAARFLQLCDAFALPVLSLCDTPGFMVGPDSEDAAAVRRVSRQFIAGAKLRSPLFTIVTRKGYGLGAQAMAGGSFHSPAFIAAWPTGEFGGMGLEGAVKLGYRKELEAETDPVKQKALYDQLVARLYAAGKATSMAAALEIDAVIDPADTRRWVIGGLDAAAGVSRPWEVRVDSF
Protein: Cyclin-dependent kinase inhibitor 1 (A5WWG2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- cyclin-dependent kinase
- G1/S-specific cyclin-D1
- G1/S-specific cyclin-E1
- Cyclin-dependent kinase 4
- Cyclin E2
- Cyclin-A1
- S-phase kinase-associated protein 2
- Cellular tumor antigen p53
- Cyclin D3
- Cyclin D2, a
Sequence:
MAAHKRILRSLGNGPTRRSLFGPVDREQLQREYRAALRRDLEDASRRWSFDFASEKPLEGGDFHWEGVSGVRVPLLYRACQEKQQKRPCEAHQPGQSAAGKENIPKTPERCAALPHEVEKTPEKSSELKRKQTNITDFYQAKKRLVATPRKSGQ
Protein: Tubulin-folding cofactor A (AtTFCA) (CFA) (Protein KIESEL) (TCP1-chaperonin cofactor A) (Tubulin-specific chaperone A) (O04350)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Tubulin-folding protein involved in the control of the alpha-/beta-tubulin monomer balance. Functions as a reservoir of bound and non-toxic beta-tubulin. Required in the developing embryo.
Interaction partners:
- Tubulin-folding cofactor C
- Prefoldin subunit 1
- COX assembly mitochondrial protein
- Ribosomal protein L18e/L15 superfamily protein
- Ribosomal protein L31
- Tubulin beta-9 chain
- Prefoldin subunit 2
- Sucrose nonfermenting 4-like protein
- Defensin-like protein 196
- Tubulin-folding cofactor B
Sequence:
MATIRNLKIKTSTCKRIVKELHSYEKEVEREAAKTADMKDKGADPYDLKQQENVLGESRMMIPDCHKRLESALADLKSTLAELEETDEKEGPEIEDAKKTVADVEKQFPTEDA
Protein: Homeobox protein OTX1 B (zOtx1) (Orthodenticle homolog 1 B) (Q91994)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Iroquois homeobox protein 1, b.
- Paired box protein Pax-2a
- Odorant receptor
- Odorant receptor, family H, subfamily 132, member 2
Sequence:
MMSYLKQPPYAMNGLGLSGAAMDLLHPSVGYPATPRKQRRERTTFTRSQLDILEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSSTKTRPAKKKSSPTRESTGSESSGQFTPPAVSSAGSSSSSSSSTNNTGISSTSTSISTVSSIWSPAISPGSAPPSVSLPEPVAPSNTSCMQRSVSGTASSTYPMPYNQTTGYSQGYPTPSGSYFSGVDCGSYLAPMHSHHHPHQLSPMTASSMPTHPHHHISQSSGHHHHHHHQAYSGTGLAFNSSDCLDYKEQTASSWKLNFNTTDCLDYKDQASWRFQVL
Protein: Antifungal lectin PVAP (P84869)
Organism: Phaseolus vulgaris (Kidney bean) (French bean)
Function: Has strong antifungal activity against M.arachidicola with an IC(50) value of 9.8 uM but lacks antifungal activity against F.oxysporum and B.cinera. Has hemagglutinating activity towards rabbit erythrocytes. Has antiproliferative activity towards L1210 tumor cell line with an IC(50) of 3.6 uM. Lacks mitogenic towards murine splenocytes and does not inhibit HIV-1 reverse transcriptase.
Interaction partners:
Sequence:
SNDIYFNFQR
Protein: RNA-directed RNA polymerase (EC 2.7.7.48) (Protein P2) (P11124)
Organism: Pseudomonas phage phi6 (Bacteriophage phi-6)
Function: Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them.
Subcellular location: Virion. Note=Found in the capsid (12 copies). Prior to RNA packaging, localizes on the inner procapsid surface near the three-fold axis of symmetry.
Interaction partners:
Sequence:
MPRRAPAFPLSDIKAQMLFANNIKAQQASKRSFKEGAIETYEGLLSVDPRFLSFKNELSRYLTDHFPANVDEYGRVYGNGVRTNFFGMRHMNGFPMIPATWPLASNLKKRADADLADGPVSERDNLLFRAAVRLMFSDLEPVPLKIRKGSSTCIPYFSNDMGTKIEIAERALEKAEEAGNLMLQGKFDDAYQLHQMGGAYYVVYRAQSTDAITLDPKTGKFVSKDRMVADFEYAVTGGEQGSLFAASKDASRLKEQYGIDVPDGFFCERRRTAMGGPFALNAPIMAVAQPVRNKIYSKYAYTFHHTTRLNKEEKVKEWSLCVATDVSDHDTFWPGWLRDLICDELLNMGYAPWWVKLFETSLKLPVYVGAPAPEQGHTLLGDPSNPDLEVGLSSGQGATDLMGTLLMSITYLVMQLDHTAPHLNSRIKDMPSACRFLDSYWQGHEEIRQISKSDDAILGWTKGRALVGGHRLFEMLKEGKVNPSPYMKISYEHGGAFLGDILLYDSRREPGSAIFVGNINSMLNNQFSPEYGVQSGVRDRSKRKRPFPGLAWASMKDTYGACPIYSDVLEAIERCWWNAFGESYRAYREDMLKRDTLELSRYVASMARQAGLAELTPIDLEVLADPNKLQYKWTEADVSANIHEVLMHGVSVEKTERFLRSVMPR
Protein: Aldo-keto reductase family 1, member B10 (S4R2G9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAAFVTLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQMIKAVFSAVNIRSWMLGRPWRNWWTRGW
Protein: Toll-like receptor 2 (E9PTD9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle, phagosome membrane {ECO:0000256|ARBA:ARBA00004596}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004596}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
Interaction partners:
- Toll-like receptor 1
- Toll-like receptor
- Toll-like receptor 4
- Myeloid differentiation primary response protein MyD88
- High mobility group protein B1
- High mobility group protein B1
- Platelet glycoprotein 4
- Toll/interleukin-1 receptor domain-containing adapter protein
- Lysosome membrane protein 2
- Toll-interacting protein
Sequence:
MLQALWLFWILMAVIGLSREGHSAQASLSCDAAGVCDGSSRSFTSIPSGLTANTKKLDLSFNKITYIGHGDLRACVNLRVLTLESSGINTIEGDAFYSLGSLEHLDLSNNHLSSLSSSWFRPLSSLKYLNLMGNPYRTLGETSLFSNLTNLQNLRVGNVDTFSEIRRIDFAGLTSLNELEIQVLSLGNYESRSLQSIRDIYHLTLHLSESAFLLGIFADILSSVRYLELRDTNLARFQFSELSVDEINSPMKKLAFRNADLTDKSFNELLKLLRYILELMEVEFDHCTLNGVGNFNPSESDVVRELGKVETVTIRSLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACEGGWPSLQSLVLSQNHLRSIRKTAEILLTLKNLTALDISKNSFQPMPDSCQWPGKMRFLNLSSTGIQAVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQELYISRNKLKTLPEASLFPVLQVMKIRENAISTFSKDQLGSFPKLETLEAGDNHFICSCELLSFILERPALVHVLVDWPDSYLCDSPPRLHGQRLQDARPSVLECHQAALVSGVCCALLLLILLLGALCYHFHGLWYLRMMWAWLRAKRKPKKAPCRDLCYDAFVSYSEQDSYWVENLMVQQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILVLLEPIEKKAIPQRFCKLRKIMNTKTYLEWPLDEGQREVFWANLRTAIKS
Protein: Alkaline phosphatase 4 (EC 3.1.3.1) (Q24238)
Organism: Drosophila melanogaster (Fruit fly)
Function: Important role in neural and renal epithelial function.
Subcellular location: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Interaction partners:
- IP06402p
- GTP cyclohydrolase 1
- 6-pyruvoyl tetrahydrobiopterin synthase
- Thiamine pyrophosphokinase 1
Sequence:
MHCLVILGFLLGSLVAFSWAGVTTQPPPLIRTLSAGGDIGPQFDVGKTKEPEDAEFWHNVGLRQLEKTIKQAQRVKEDSYQKKARNIIIFIGDGMGISTISAGRIYKGQYLKHGYGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATAIFSGSKTHYGAIGMDATRSKKNGQQGRVQSVMEWAQKEGKRTGVVTTTRITHATPAATYAHIYDRDWECDTEVPAESVGFHVDIARQLVENAPGNRFNVILGGGMSPMGILNASEVKTTIFEGPTETICTRGDNRNLPAEWLAHHANDTVPPALVHNRKDLLNVNVKKVDHLMGLFRNNHITYSIAREAGEPSLQEMTETALGILERGDESNGFVLLVEGGRIDQGHHMNYARAALHELYEFDLAIQAAVNNTDPDETLILVTADHSHAVTFNGYALRGADILGTANSHEKNDPMFYETISYANGPGYWDHLANDSRPQNSSNMWMPLKHFTAEERAAPTYRHLATVPRKDETHGGEDVAVFAYGPGSSLIRGVFEQNYLAYVMSYAGCLGPAKDFDDSCEDHKDGQKDRPLDKPNPKRNGATVVGASLIPILTAATAAILRGRGL
Protein: Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein) (Q99459)
Organism: Homo sapiens (Human)
Function: DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Subcellular location: Nucleus {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:11544257, ECO:0000269|PubMed:18583928, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:29301961, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:29361316, ECO:0000269|PubMed:30705154, ECO:0000269|PubMed:30728453, ECO:0000269|PubMed:9038199, ECO:0000269|PubMed:9598309}. Nucleus speckle {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:10827081, ECO:0000269|PubMed:11544257}. Cytoplasm {ECO:0000269|PubMed:9038199}. Note=May shuttle between cytoplasm and nucleus. {ECO:0000269|PubMed:9038199}.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase-like 1
- Pre-mRNA-splicing factor RBM22
- Spliceosome-associated protein CWC15 homolog
- Splicing factor YJU2
- Small nuclear ribonucleoprotein E
- Pre-mRNA-splicing factor SYF1
- Small nuclear ribonucleoprotein Sm D3
- ATP-dependent RNA helicase DHX8
- RNA helicase aquarius
- Pre-mRNA-splicing factor SYF2
Sequence:
MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKSKF
Protein: Pectate lyase (EC 4.2.2.2) (F4JW80)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable serine/threonine-protein kinase PBL10
- Probable serine/threonine-protein kinase PBL11
- Pectin lyase-like superfamily protein
- Probable polygalacturonase At2g43860
- F3F20.11 protein
- Pectin lyase-like superfamily protein
- F3F20.10 protein
- Pectin lyase-like superfamily protein
- Pectin lyase-like superfamily protein
- F5I14.10
Sequence:
MVAHERRIHNLQKPTCICIIWFCLLVSLSHHGRASSTSASIFNLSLPHQHPFPEHVVLNVQRKLNDSLSRRQLLTYQQDDGTTASSPIPSCITGNPIDDCWRCDPNWSANRQRLADCSIGFGQGTLGGKGGQFYLVTDSSDNDAANPIPGTLRHAVIQPEPLWIIFSSDMGIKLKHELIIGSYKTIDGRGTNIQITGHGCLTIQQVSHVIIHNVHIHHCKPSGNTLVASSPTHVGFRGVSDGDGISVSASHHIWVDHCSLGYCADGLIDVILASTAVTISNNYFSHHDEVMLLGHDDRYTADKGMQVTIAFNHFGEGLVQRMPRCRHGYIHVVNNDFTAWEMYAIGGSASPTINSQGNRYTAPIDPNAKEVTKRVDSNEKHWSGWNWRTEGDVMVNGAFFVPSGDGVSPAYARATSVQPKAAAIIDQLTVNAGVFGDPSGRNGQGGSFPGITNGGGTITRGYSKSGPAGGGSGSDSDDGLFTLIFGNNSGAVALRPGQVWSILLIIILYWYIPHHTRS
Protein: Carboxypeptidase (EC 3.4.16.-) (Q5JZH0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRTLLWSRIWATSSLACHSSGCGIRHCCAQGIKCAWTPPAPTQQLLPPTSTTRTCGRPSTSRSSCHNGTCASEVPWPPVTWGGGLLGLVGIGRFLRDLLCRVSQ
Protein: GM13370p (Q95S27)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSRKHRGSENMENLCPVTRKRSTNKNHVSVVGALVSTTKSSHYEHPSSPSALTFEALEEMGIGMLDSEESSSSALSAIALAVSATSDDNSNETTPCASVSRMAHQLQHTQRLSLGSTGDITLDSPAVEDSLSMSRQSAEKLQILAQAKRSSLGSEGSGNSNSPSKRLRNPLAAVTCNNQIDGTASLNFQPSTSRLAQVRQAKKPSTTNITTRIVAADSFFVFRTPAMSAHINSGINYFERLSDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDLGLRTIRPGALEQIVRRGVLVIRLAQTSVSYI
Protein: 3-oxoacyl-(Acyl-carrier protein) reductase, putative (Q585V0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- beta-ketoacyl-[acyl-carrier-protein] synthase I
- Short-chain dehydrogenase, putative
Sequence:
MPWNLQGRVAVVVGASSTVGRQVASRLADEHRMRLACVSRRGCGSSLPSGCVAFKADLTVAPESDTVMKQVKETLGPVSLLVNCAGVTLNKIHVRCTDTDYDVLMNVNLRGALHITRSALRHGGMLQVGDGSVVHIGSLVGCMGNEGQVIYSASKAALSGAVKSWAREYGPKNIRFNVIAPALIEGEGMATTLTENQIEEWRQRCPLRRLATVTDVVDAVVGVACCPFISGQTIHVDGGMW
Protein: Oligodendrocyte transcription factor 1 (A8WIQ7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- DNA-binding protein inhibitor ID-4
- Transcription factor SOX-10
- Homeobox protein Nkx-2.2a
- DNA-binding protein inhibitor ID-4
- Myelin regulatory factor.
- Platelet-derived growth factor receptor alpha
- DMalpha1
- 2',3'-cyclic nucleotide 3' phosphodiesterase.
- Myelin-associated glycoprotein
Sequence:
MQAVSGVRYREQGESSLQQLMPRMVRVTGSGGPGSNVGSLQGPLRSSKPPRELSSEEQQELRRKINSRERKRMQDLNVAMDALREVMVPYSSSPTGVGGALQHPYLPPGAPTTGRRLSKISTLVLARNYILLLGSSLQEMRRLLGEVSIGMGVSGTVPRLLLTGGWPFLTGPGQLLLSPPEQQLGVAKCPLLPQGAQEEPLAWGPGSMSESPVCQCGVCRTPRVVHVNPAMRFPK
Protein: GH22922p (Leucine-rich repeat activity-regulated protein at synapses) (Q9W2J7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Radish, isoform I
- RE59088p
Sequence:
MELHWQLLTFIVCLQLLHSAGFIIQSEVRKCTYGHIDKLLRIRCYDLDLKEVPQNLKSSVEVLDLSHNRIRKLKTSSFQRYTDIKFLMLYDNMILSVEVGTFEPLTSLQEIDLSNNGLTTIPLELFQLPRLRNLYIDSNELTSLNLQALEKPIRAPLEYLNVAGCELQELPDLGILPKLWQLNASMNPLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQQVTNHLMMLGASPKFVPVCLEALDIRECPLPYNRTIHSPTFASCQTTLQFAETRSFWLFGAGCFGGVCFVLLIVIFCVIHCRRKRAQRRKRNAQKRKPFVISPRNAINNRQPEDEPLHCDIARK