wanglab/gogpt-training-data huggingface dataset:
Protein: DNA repair protein Mre11 (Q8T8P1)
Organism: Trypanosoma brucei brucei
Interaction partners:
Sequence:
MGSRVTVLHIIMAERASTQSHALPTSTQADPSLAASTFKFLVTSDNHLGYQERDSRRGDDSFTTFEECLRAARVEHEVDAILLAGDFFHDNKPSLGCLARTSSLLRSYVLGDKPISFTLLSDPKRNFPTHPVPLANFQDPNINVALPIFMIHGNHDDPVGGTSSIDILSTAGLVNYFGHTSSLDDIVVEPVLLKKGDTYIALYGLGNVRDDRLHRCFRMKKLHFVQPKTEPGKDWFKILLFHQNRGVRSGGNMKCGIYETMLAGHGMDLVIWGNEHEQQMEPSPSEGFDIIQPGSTILTSLSEHECNPKKYGVLEVRGGSYRVTGFPLRSIRPVVRRTVELWRDNPGCRTLDAVEDFLRSVVEQMIEEAEEQVSRIPDDVLKFHPNIKFPIMRLAVDFTDPDSTTFPQPNINRFGQQYMDIVVNPSELLRPIKPKQVPRVASSASATGGEAPVVPVPRLNTSDIRTKVAEVFNANARDACSLLSESEVSAAVYAFAEKGERDAIDERICELLSKCQKSVWVSMRRGESESILKPESIYEEVVRHKKEANKRYEELSRAAEEALQRSTQGNELTERLRADTELAASMDSGNFSRVGGELADGAALGLLSATAPRRAGGSGATNNGEGANDALSQVGFTFPDFSNSLSPPDASGGAATRGKRSRDELNVFDVATERDTNEVNSHPNVSTVKGGGKAVKSETSAPKPARGRKPKRPVDGGVNGLPLFPSLELTREPVPDENFLLPPVVGGGVQGASTSSSGMPDNY
Protein: Endoplasmic reticulum membrane protein complex subunit 7 (ER membrane protein complex subunit 7) (Q9NPA0)
Organism: Homo sapiens (Human)
Function: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:22119785}; Single-pass type I membrane protein {ECO:0000269|PubMed:32439656}.
Interaction partners:
- ER membrane protein complex subunit 5
- ER membrane protein complex subunit 1
- ER membrane protein complex subunit 10
- ER membrane protein complex subunit 9
- ER membrane protein complex subunit 4
- ER membrane protein complex subunit 8
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 3
- ER membrane protein complex subunit 2
- Protein C1orf43
Sequence:
MAAALWGFFPVLLLLLLSGDVQSSEVPGAAAEGSGGSGVGIGDRFKIEGRAVVPGVKPQDWISAARVLVDGEEHVGFLKTDGSFVVHDIPSGSYVVEVVSPAYRFDPVRVDITSKGKMRARYVNYIKTSEVVRLPYPLQMKSSGPPSYFIKRESWGWTDFLMNPMVMMMVLPLLIFVLLPKVVNTSDPDMRREMEQSMNMLNSNHELPDVSEFMTRLFSSKSSGKSSSGSSKTGKSGAGKRR
Protein: Arrestin domain-containing protein A (Q54CH1)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Arrestin domain-containing protein F
- Arrestin domain-containing protein C
Sequence:
MNYQVTVSGDPELAQESVDFVSSGFGNMSMNVNTTSSHHHHHSNSGNAEVSFNGGFGMPNMTMEVKETHSGHHHHHSNGGNAEISINSGFGMPSMTMSVTDSNSGHHHHHHKESASVNLSLGGIVGAVVGAVTGGVMIDGRNRIWVQLNQSSYVGGDIISGTIEMDCIVPFFAKGVIVKVKGFERLWLQELRTETEGEGSNKRTVYKTIDHKENKEFFKSTIVVYPQAGTVNCGHYSFPFSYQLPSDLPGTFCHDGKDAMGAYSAKILYKCKATVDVAHKHDLKSTTKLIINEKCGELVQPSFAENKKSFMLTKGKLHVKTWLNKNAYFPGETLVAKMKANNTSIKPTRKISLVVHHTMQLKTRLYHRCITNAIYKQQYDGFQPCFYGKRYLPFSIPVDLKPSSSLGKHITSSYLLELECDIPMAIDLSVTLPLTLFAPQFLYSTVPSQPPGTPLPPDVSYRHPWEGDEHATACRKCNKGFSLFARKHHCRHCMKIFCDKCTSTKTTITKLAYPKPVRVCEECYPIATQGGNKYQSAKLMAAQYQASLNAYYAQYASLYPQIYPDQQQQQQQPSAPPQQY
Protein: Ion transport domain-containing protein (Q688B2)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSERKKSLITTINNQRKYSQVAKAAVLSSAMLARKNSSSRGAPGSAAGFGARESIAAISDMLSSQHKKPVRSSYVESDRVEWALKIACTISMITVCIHTPRTIELFQPLNYIILAADFISVSIFMLDSVLRIHYEGIFRCDSSYLSNRWSQFSVFISIIHLLSFLLHCYQLIDNFFPFLHLNYRAWYGAIRSIRPFIIIRLIPLVVKFKLPKNRIEQLLKRSSQQVKNVTLFFVFFMTLYAIFGIQLFGRMDYHCVQPKTDPNNVTIMDLAIPDTMCAPEGIGGYECPAPMVCMQLNLNAKGEGFYGMFNDFGASVFTVYLAASEEGWVYVLYDCMDSLPSYLAFLYFCTLIFFLAWLVKNVFIAVITETFAEIRVQFSEMWQKKEVTLDEGFRKKLEKTDDGWRLIRLDGEVEPEGPKQKLQWMLRSMYFQCFVIIFVVINAIGNAMFVYRHDETDKPRKYNFYLFEVGFTILFNVECIIKILCYGFRNFIRRGIFKFELILCLGSSLNCVKFFYERNYFTYFQTFRLLRLIKASPILEDFVWKIFSPGKKLGGLVIFTIAFICCYSAISLQLFYSVPNLHHFRTFPQAFMSMFQIITQEGWTDFVVEVLRATDDNLVPLVALYFVAYHLFVTLIVLSLFVAVILDNLEMDEELKKVKQLRAREATTSMRSTLPWRLRVFEKFPTRPQMAAMRKADSDFPMPKVRGSFTHQFAVDHSLETTDVIESDFEFPKRIMKSAGKRKISKSGLTFRQIGSTSLRCSLNNLLEMSDRTRQSLSNSLSFLPHFTRSSGSLYPRKDALPKSRSMTGKFLQTAVRNKQFNMYSENGDLSRPSDSAPKKNAKQGEIDIRALQQKRQLAEITRNRIEEDMRENHPFFDRPLFLVGRASQLREFCKKMVHSKYDSQDDGTNGGAKTKKRFKEIRALIGIMPYIDWAMATVTIVSCISMLFESPWPTTGENLVMNNGYLQISDYFFVLSMTFELCVKIIANGLFFTPKAVVRDVGGVMNLFIYFTSVIFLAWMPKHVEINSLAQFLMICRAMRPLRIYTLVPHIRRVVLEFFRGFKEILLVTILMIVVMFIFASFGVQIVGGKLAACNDPTVSSRENCTGVFWQKLFVTRLEVYGKDTEAMHPKIMVPRVWTNPRNFNFDHVGNAMLALFETLSFKGWNVIRDILWSRHGPWAVVFIHIYVFIGCMIGLTLFVGVVIANYTQNRGTALLTVDQRRWHDLKARLKMAQPLHVPPKPSESARLRTKLYDLTMSRWFNQAFALLVVLNSFTLVIPWNVEEEEQRATYVFTVTALAAFMNMLFVIEIILKVIAYTFSGFWQSRRNRVDLLITVFGVIWIFLHFFVALPSSKIDVDVQVELKKFTYTFGYLVVILRFFTIASRNSTLKMLMLTVIMSMFRSFFIITALFLLVLFYAYTGVILFPMVKYGMAVSKHVNFRTASEALVVLFRCLTGEDWNDIMHDCMRSAPFCYWNEGMNYWETDCGNFYGAIIYFCSFYLIITYIVRNLLVAVIMENFSLFYSSEEDALLSYADIRNFQYVWNMVDQEQKRTIPVERVKFLLRLLKGRLEVDPEKDRILFKHMCYEMERLHNGEEVSFHDVLYMLSYRSVDIRKSLQLEELLQREELEFIIEEEVAKQTIRTWLEGCLRKMRNPSQKDAEGVLPFGGGHPVIHSSGHSSISHEETVAQRLRFENIRGDSVDTEETESSEEETPPPIRKKAAVKNRRGSIPDVLSRTGLFQEAARKFMVGSSSEKKQVKSRSPETVQLLPKRANSEIRKGSGQPKNFHLQLNVYDLPDVEERGEDSPFSPKNLSDDFNGEHSPLVITPSLPVPPTHGSPRPLMPCETTKDIEKWWNSLVD
Protein: Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Q5EB59)
Organism: Rattus norvegicus (Rat)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Also required for transcriptional activation subsequent to the assembly of the pre-initiation complex. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 15
- Mediator of RNA polymerase II transcription subunit 24
- Mediator of RNA polymerase II transcription subunit 14
- Mediator complex subunit 12
- Mediator of RNA polymerase II transcription subunit 1
- Mediator of RNA polymerase II transcription subunit 25
- Mediator of RNA polymerase II transcription subunit 28
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 17
Sequence:
METQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLAAFRQFWNGLSQESHEQCVQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRVPLPGTSCLASASVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSHRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMTFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTDENEIITQFSMQGFPPLFLCLLWKMLLETDHISQIGYKVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQSDWHTKHMSYHKKYPEKLYFEGLAEQVDPPVPIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMCLRNRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKHAMNAREDNPWVPEDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSSSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPVVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAVPPQALSSGSPAPQANQVPTALPVTQ
Protein: Phospholipase A2-delta (EC 3.1.1.4) (Secretory phospholipase A2-delta) (AtsPLA2-delta) (Q8GV50)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli. Plays a role in pollen development and germination and tube growth.
Subcellular location: Secreted {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:21278126}.
Interaction partners:
- S-protein homolog 12
- Lecithin-cholesterol acyltransferase-like 4
- Myosin-7
- Glycoprotein membrane GPI-anchored
- F-box protein At1g19070
- At1g27330
- T29M8.11
- LAZY1
- F-box/kelch-repeat protein At3g06240
- Protein HOMOLOG OF MAMMALIAN LYST-INTERACTING PROTEIN 5
Sequence:
MIRGGALTHVALGLTVFLLLAVVHSQEKCSKTCIAQKCNVLGIRYGKYCGIGYFGCPGEPPCDDLDDCCMTHDNCVDLKGMTYVDCHKQFQRCVNELKQSIQESNNQKVGFSKECPYSTVIPTVYRGMNYGIFFSGIGNIIIPKKPASAGPVVEVDLARSKADTKDGLGTNQGPQTKDGSKVSVPMNPSPS
Protein: NAC domain-containing protein 23 (ONAC023) (OsNAC6) (Protein THERMOSENSITIVE MALE STERILITY 5) (B8AE67)
Organism: Oryza sativa subsp. indica (Rice)
Function: Transcription factor involved in the regulation of seed size. Possesses transactivation activity in yeast.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353}. Cytoplasm {ECO:0000269|PubMed:27872632}.
Interaction partners:
Sequence:
MAMTPQLAFSRMPPGFRFQPTDEQLVVDYLQRRTAAQPCVTPDITDIDVYNVDPWQLPAMAMYGSDHDRYFFTMAAREAQARRTTPSGFWKPTGTKKTIFVVAGGHEVPTAVKRRFVFYLGHHQPSGSSNNNKTSWIMHEYRLMNSPRAAVPSSSSVNRLPTDDLTEEMVLCRISNKDLPKPPFIHNGLLQFSSVGLNGDGYNYLILDHLEPPAMEYPNVDIGNVDDAAAADDDPGDLDEEIDDSMQRNHGG
Protein: Protostome-specific GEF, isoform C (E1JJB8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPTMTRMHRHSSSSAVVEESRGRRRGVGVPGVGDANKENFGVHFMSSPFGNASLIALQDLSNVHGKSPQRRSFSEGSGPRQATPQLAALRCLPRTTGGAVALEDSQLSSSRMGDTTLDRMLDAIIESARKEVRCTKTLPGAGATTSTTILADNAEWSETSVHEMEVRTPTHLKRQRVVRRKNPHKTTTINQTQSHQAKKLEPLQLVPSTKRCLSFSSSSASSDLDEDEQQVAKRSSLASPTTTPPSHCTTTTSSISSSSSSNGGADMEASQRGSIDVSIAFDAKEQQLNVHVIRCRDLQRSHGSGNGSINAYVKVALSGGAQPPGYGGHSSGGSMSSGYQRTAVHRHSGRPYFDQRFNFQISSGEETAGQYLQLAVWHRDRHLKRSEFLGCSTFPLNELVHPDSGVSAGSYKLHAQACPPPTSRHSQPKANAGQDQKQETEAAKDQDKQQDDSPAEMAAAVTVTPQKPVATGSGSGSNSAAMALNDEVISISIDSMGKEDPLLPQQPQQPMKLSKKALHQRDADENLFLRFLELDPPADGNANSTTTQAQATGSQSSASKANESNANHLNNGTSGGRRQSTMPNSGGSSVGGAVRQQQGRTPFTMTKRLTRTEERGFGFSIVWTHPPRVEKIEAGLSADRCGILPGDYVIFVDKHNVVTMPEADVLNLIRSQGSSLTLEIFRRSGAGATTITSTDLGQNNVHISTRLGAAVGLGSEEHTLATTATGTTTVMSLQRTTSTRIQPLANSMSRPATACSGTTSSIEAAKRRLHLPQVTFSKESIVPVTDNRRRFLLQLISREQNFTAALHFGVDRFVQPLGERKDLISPNDHRTLFQNIDELLRIAEDILEQLCSSDQQDQEPQMNFASRVYLSKTTAICAAYKKYCNGIKRADCVLVNKSRQTGSEFIAFITEPAVPRKRPDLTMFIHRPLQHFREILKLMQLLAGNCHVDTEEHKNFSTVINELQAAYREITVSSGLMEPLGEGRPLLTLQDLESRMVFTKCKPFTLAVQGRQWIFGGDLSRVEGRSVKPYWTLLFSDIIVFAKVSRDRVLFITEEPIPIANVVDSCFHMRKKTTEFRLTVDPNGRLAESPTGYCAPDLTRTPKRGARRKSLILRAPSLELKAVWQNLLQRQIFLVNAALGSTPLSSPLDSPDVLNTLVPLSDIGLTTASMGSMKLPSLDSIHLKQQQKQQVRLFRSKRLDSGDSYENLQRLASAVRHHCASTTTSSATQTQSHPQPPLCTTSLPSRTNSPARNQRHPNGQGHVGGSVPNGVGGVSFGGCNTNSSCLSSSASLTQTQTQVHTQTLNHSQTHSQTQTSVLSLSSCKCLTVIPEVTSEPPVNQHASQKLLEFSLSSVGRSFIDESGGVVGGQVSLTTPETPTPNISPTTSQPCNSDAFSNDFVATSTTGKGPNIPLAEFGGSWDLLELDLQLHEVNLDPSYDTDVEECIFLGDEEDREGTEGHGHDEDSDEDDSVVVDDPFGMLPTRPTPPDSLDL
Protein: CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2) (CD antigen CD209) (Q91ZW9)
Organism: Mus musculus (Mouse)
Function: Probable pathogen-recognition receptor. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens.
Interaction partners:
- Lymphocyte-specific protein 1
- Intercellular adhesion molecule 2
- Scavenger receptor cysteine-rich type 1 protein M130
Sequence:
MRMHTRLQFLKRVSNVAYSHGQEQAKKEKVYKEMTQLKSQINRLCRPCPWDWTVFQGNCYFFSKFQQNWNDSVNACRKLDAQLVVIKSDDEQSFLQQTSKEKGYAWMGLSDLKHEGRWHWVDGSHLLFSFMKYWNKGEPNNEWEEDCAEFRGDGWNDAPCTIKKYWICKKSAMSCTEK
Protein: Eukaryotic translation initiation factor 4E (H0Y8J7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETEGIQGKVRTSSKDSDWLSVPRRHSY
Protein: Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1) (P02763)
Organism: Homo sapiens (Human)
Function: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Subcellular location: Secreted.
Interaction partners:
- Alpha-1-acid glycoprotein 2
- Albumin
- Alpha-1-antitrypsin
- Haptoglobin
- Serine palmitoyltransferase 1
- Alpha-2-HS-glycoprotein
- Ceruloplasmin
- Protein AMBP
- Alpha-1-antichymotrypsin
- Serine palmitoyltransferase 3
Sequence:
MALSWVLTVLSLLPLLEAQIPLCANLVPVPITNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQDQCIYNTTYLNVQRENGTISRYVGGQEHFAHLLILRDTKTYMLAFDVNDEKNWGLSVYADKPETTKEQLGEFYEALDCLRIPKSDVVYTDWKKDKCEPLEKQHEKERKQEEGES
Protein: Trehalose-2-sulfate acyltransferase PapA2 (EC 2.3.1.288) (2-O-sulfo trehalose long-chain-acyltransferase) (Polyketide synthase-associated protein A2) (P9WIK7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Required for the biosynthesis of sulfolipid-1 (SL-1), a major mycobacterial cell wall lipid. Catalyzes the acylation of trehalose-2-sulfate by adding the palmitoyl group at the 2'-position to yield the intermediate trehalose-2-sulfate-2'-palmitate (SL659).
Interaction partners:
- Phthioceranic/hydroxyphthioceranic acid synthase
- Probable multifunctional mycocerosic acid synthase membrane-associated Mas
- Trehalose 2-sulfotransferase
- Mycocerosic acid synthase-like polyketide synthase
- Phenolphthiocerol/phthiocerol polyketide synthase subunit C
- Polyketide synthase Pks13
- Mycoketide-CoA synthase
- Mycolipanoate synthase
- Possible electron transfer protein FdxB
- Sulfolipid-1 exporter MmpL8
Sequence:
MFSITTLRDWTPDPGSIICWHASPTAKAKARQAPISEVPPSYQQAQHLRRYRDHVARGLDMSRLMIFTWDLPGRCNIRAMNYAINAHLRRHDTYHSWFEFDNAEHIVRHTIADPADIEVVQAEHQNMTSAELRHHIATPQPLQWDCFLFGIIQSDDHFTFYASIAHLCVDPMIVGVLFIEIHMMYSALVGGDPPIELPPAGRYDDHCVRQYADTAALTLDSARVRRWVEFAANNDGTLPHFPLPLGDLSVPHTGKLLTETLMDEQQGERFEAACVAAGARFSGGVFACAALAERELTNCETFDVVTTTDTRRTPTELRTTGWFTGLVPITVPVASGLFDSAARVAQISFDSGKDLATVPFDRVLELARPETGLRPPRPGNFVMSFLDASIAPLSTVANSDLNFRIYDEGRVSHQVSMWVNRYQHQTTVTVLFPDNPIASESVANYIAAMKSIYIRTADGTLATLKPGT
Protein: Matrix protein 2 (Proton channel protein M2) (C5E519)
Organism: Influenza A virus (A/New York/1682/2009(H1N1))
Subcellular location: Virion membrane {ECO:0000256|HAMAP-Rule:MF_04069}. Host apical cell membrane {ECO:0000256|HAMAP-Rule:MF_04069}; Single-pass type III membrane protein {ECO:0000256|HAMAP-Rule:MF_04069}. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion). {ECO:0000256|HAMAP-Rule:MF_04069}.
Interaction partners:
Sequence:
MSLLTEVETPTRSEWECRCSDSSDPLVIAANIIGILHLILWITDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYQQEQQSAVDVDDGHFVNIELE
Protein: Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (O42962)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as essential component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi apparatus membrane {ECO:0000269|PubMed:16823372}; Peripheral membrane protein {ECO:0000269|PubMed:16823372}; Cytoplasmic side {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 2
- Conserved oligomeric Golgi complex subunit 1
Sequence:
MEFRYDFSDYKKSDFDPKAQAERVLISVHADSDVNEDKEVARKRLGYALKEVERQITDLIVHEETTLTKNVSSSLNAQSYLQDIEGKLEQLMLVYERIRSLVVIPSENLGPLHEAIVNLHSTYMTLYWLGEFFGIQAKLFPLFQGSINENEKLSRYYQASLLLQESDQLLSRFPLMKRQSSVSLLLKLNITNRSRIIKETSSYLLSQEDQLSFSVNSNGFTNACSVLYMLDKYLLEQDLTRLLSSRIQKAIIQFDSIFQLSPTTRRLLHNSTDPSAANSTIWSKFEDGWYQISKIGAQCVFWERSLQKANICNPDYPNLLEYFQMQPNFILDGATICIYFFKELAISISSKMQMLDRRDPILLRVFRSDFQRVTHIVEQAIARSSSEIVNKDTRECSIVMNSLRVLAPKNP
Protein: Octapeptide-repeat protein T2 (Q06666)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MQRGREREAESQRVRESERQRGREAERQRERQRGREAERQRGRERGREAEREAERQRGRERQRGRGEAERQRGRERGREVERHRRGREAERQRGREREAERQRGREAEREAERQRERQRERQRGREAERQRGREAERQRGREAEKQRGERQRGREVEAEAEGRGRGMRQEAEATEQGQGQRQRQR
Protein: Transketolase (TK) (EC 2.2.1.1) (Q556J0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Interaction partners:
- Glucose-6-phosphate isomerase
- Ribulose-phosphate 3-epimerase
- Probable transaldolase
- Fructose-1,6-bisphosphatase
- Ribose-5-phosphate isomerase
- ATP-dependent 6-phosphofructokinase
- Fructose-bisphosphate aldolase
- Glyceraldehyde-3-phosphate dehydrogenase
- Phosphoglucomutase-1
- Triosephosphate isomerase
Sequence:
MSNIDFKALERAANETRGLSMDAVAKAASGHLGLPLGSAEIGAALFGNSLIYNPKDTRWLNRDYFVLSAGHGSMFLYSWLHLSGYDVSIEDIKNFRQLNSKTPGHPKFHDTPGVEATTGPLGQGIANAVGIASACKMAAGKFNTEQHQIFNQKVVVLVGDGCLQEGISQEAISFAGHHRLDNLIVFYDSNDVTLDAMAIETQSEDAVKRFESVGFEVQLVLEGNNIGSLINAYQNAKHSKSGKPQIIICKTTIAKGIPEVAGTNKGHGEAGVKFIDSARKNLGLPEEKFFVSGETRQYFEQHEKQLEKLYQEWQATFAEWKSANPKLAQLLESAHEKHEAIDIMKQIPEFPTTPIIATRKAGSDVLQPISQYLPLSVSGSADLHGSTLNYIKEGRDFTPACPTGRNIKFGIREHAMGAMMNGIAYHGLFKVSGATFLVFSDYLRPAIRLAALSHLPVVYIFTHDSVGVGEDGPTHQPVETVSGLRMIPNLDVIRPADPEETAAAFSLAYARADGPTLLSLTRQNLPFLPGTAQKKREGTLRGGYIVVSETAPLRMILIATGSEVQHCVEAAKLLGDDIRVVSMPCTELFDRQSNEYKQSVLPSGCRNRIAMEAGVTSFWYKYVGLDGKVIGIDRFGMSAPGNAVMKQLGMTSENLVNISKQ
Protein: Vacuolar iron transporter 2 (OsVIT2) (Q6ERE5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Vacuolar iron transporter involved in the transfer of iron ions from the cytosol to the vacuole for intracellular iron storage. Vacuolar iron storage is required for seed embryo and seedling development (Probable). May be involved in the regulation of iron translocation between flag leaves and seeds (Probable). Can transport zinc ions from the cytosol to the vacuole.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:22731699}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the tonoplast. {ECO:0000269|PubMed:22731699}.
Interaction partners:
- Glutamate synthase 2, chloroplastic
- Ferredoxin-dependent glutamate synthase, chloroplastic
- Glutamate synthase 1, chloroplastic
- glutamate synthase
- Guanylate kinase 1
- Guanylate kinase 2, chloroplastic/mitochondrial
Sequence:
MVKEFVQDEEKQRLLLDEHTEKHFTAGEVVRDIIIGVSDGLTVPFALAAGLSGANAPSALVLTAGLAEVAAGAISMGLGGYLAAKSDADHYHRELQREQEEIDTVPDTEAAEIADILSQYGLGPEEYGPVVNSLRSNPKAWLEFMMKFELGLEKPEPRRALMSAGTIALAYVVGGLVPLLPYMFVPTADRAMATSVVVTLAALLFFGYVKGRFTGNRPFISAFQTAVIGALASAAAFGMAKAVQSI
Protein: ESAT-6-like protein EsxO (P9WNI7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Plays an important role in mycobacterial pathogenesis in the context of innate immunity. Aids host cell invasion and intracellular bacillary persistence. Increases host oxidative stress response, leading to genomic instability and decrease in macrophage viability. Also induces autophagy and modulates the immune function of macrophages.
Subcellular location: Secreted {ECO:0000269|PubMed:12919853, ECO:0000269|PubMed:17443846}. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS). {ECO:0000305|PubMed:19876390}.
Interaction partners:
- ESAT-6-like protein EsxP
- ESAT-6-like protein EsxK
- ESAT-6-like protein EsxJ
- ESAT-6-like protein EsxW
- 6 kDa early secretory antigenic target
- ESAT-6-like protein EsxN
- ESAT-6-like protein EsxL
- ESAT-6-like protein EsxB
- Probable cold shock protein A
- ESAT-6-like protein EsxI
Sequence:
MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
Protein: Uncharacterized protein (Q38A98)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTGCGCIYFVCFSFPLHLFVAYLHGGSWCTVNGSVGSVSIITVLAISSLKITMFTVRSGVVRCARLWVLFFSIHTPAIAHSASWNGKRANKQIGQLGGFWRRGAMHIHETIPVAIVDPAEPNAAPIRRHIEDRTLFAYRNMGFALTHYHSSFTGANRHPIVIENMNQLRVYHRREYTYNLLLRRTYNVKTFQTVLGIIADSREPFNNVNQLQNTKLYAYRNTSADQEVVHRFSKEAVGGSYTPPQYMRFDALITGPHASAFITSCDSITEEFVINFVRAGHYTYYLHQHLSNPRYLPAWEKIYGPRGSRPAKPVLFYIGVGPQEFPESSMSAGMQRSLHAMVERCVDCVETPPPGIAADLIPFSVRETARKYGVRLLQRWRMRYFALRC
Protein: Uncharacterized protein, isoform A (EC 3.4.21.-) (Q9VP92)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQGLLLYCLLTAPLASIEVLAQDLNQTIDVNKLAKIVQRPGFQTRVVGGDVTTNAQLGGYLIALRYEMNFVCGGTLLHDLIVLTAAHCFLGRVKISDWLAVGGASKLNDRGIQRQVKEVIKSAEFREDDMNMDVAILRLKKPMKGKSLGQLILCKKQLMPGTELRVSGWGLTENSEFGPQKLLRTVTVPVVDKKKCRASYLPTVHLTDSMFCAGVLGKKDACTFDSGGPLVYKNQVCGIVSFGIGCASKRYYGVYTDIMYVKPFIEQSIKVLLAKR
Protein: CAAX prenyl protease (EC 3.4.24.84) (A1ZAM7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU366005}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU366005}.
Interaction partners:
- CAAX prenyl protease 2
- AT13932p
Sequence:
MSAHFWDDPLAILYIIIAFLVLDNLWGVYLMLRDIQVAYKTQQVPNVISPYLPQELYDKMRVYKIHKGWFTIVNTLLSAVILGIMELYFGFYAWLYGVAGKCALSKWMEHEACVSVIFVLLLSVYFWLKSVPAMIYESCCIKSLQPRPKPPWWSRICHFVVDLVVGAMITTLVVVALVYMFIGLGPYAPLGLYLQSLILTMIVLLLIPFMIHPFVGQSVPLENSNLRTQLEYLTRQVGFPMSQVRIIRVHDPNTGSNAFFYGCCCLKRIVIFDTLLLNRGKSDLSHLTAEELGRGLADPQVVAVVAHELGHWRNGHFYKAIMAFQVHLILTILLFAFLFSHGPIYQAVGFPPGLQPTVIGCLIIFGFVLTPYMTLANFSMLSMTRCFEYQADRFAYQLGYGGELRQALLKLYADNLAFPVSDPCYSSWNHTHPTMLDRLSRLEEFRR
Protein: Type IV inositol polyphosphate 5-phosphatase 3 (At5PTase3) (EC 3.1.3.36) (EC 3.1.3.86) (Q8H0Z6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has phosphatase activity toward PtdIns(4,5)P2 and PtdIns(3,4,5)P3.
Interaction partners:
- EPIDERMAL PATTERNING FACTOR-like protein 7
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH4
- F21F23.12 protein
- F14J22.5 protein
- RING-box protein 1b
Sequence:
MSPVEPAGIMKKSHRQKSQRLWAKLVMRKWLNISGRDPEYGADTDNESENEDAREDNDDSSSDEEGGSGSRGRESKVYENAEDAIAAASAVVDAAAAAAEFISNDAPMKLRRRNSETLRAQYINNKEIRVCVGTWNVGGISPPSDLDIDDWIEINQPADIYVLGLQEIVPLNAGNILGAEDDRPVAKWEEVIREALNRVRPKLSGVKSYSDPPSPGRFKPFEETHDIIEEEVAFESDSDAGVEIHPIDEEEEEETDRLWALKHDGGVIGEVKTLVDPNTGLPVVEIKRQFSIPKKLDRQLCLRADSFKGISDDDSTQTGMKTINRMLSGKERIGLSWPEPPLNMLGPCVLDRQPSIKTVKSLKTAKSFKAYSSFKSVAGNNNGIPPEVLALAEMDLKLLMERKRRPAYVRLVSKQMVGILLTIWVKRSLRKHIQNVRVSTVGVGVMGYIGNKGAVSVSMSINQTFFCFINTHLTAGEREVDQIKRNADVHEIHKRTVFHSVSALGLPKLIYDHERIIWLGDLNYRLSSSYEKTRDLISKREWSKLLEYDQLVKEYRKGRAFDGWSEGTLHFPPTYKYQANSDEYTANDGKAPKRTPAWCDRVLSYGKGMRLVHYRRTEQKFSDHRPVTAIYMAEVEVFSARKLQRALTFTDAEIEDEGLVAVLV