wanglab/gogpt-training-data huggingface dataset:
Protein: Importin subunit alpha (Q7Z726)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPEMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGAPGTFNF
Protein: Glutathione S-transferase F9 (AtGSTF9) (EC 2.5.1.18) (AtGSTF7) (GST class-phi member 9) (O80852)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC), and glutathione peroxidase activity toward cumene hydroperoxide and linoleic acid-13-hydroperoxide. May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
Subcellular location: Cytoplasm, cytosol {ECO:0000305}.
Interaction partners:
- Probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial
- Methionine--tRNA ligase, cytoplasmic
- Putative glutathione peroxidase 7, chloroplastic
- S-alkyl-thiohydroximate lyase SUR1
- Probable glutathione peroxidase 5
- Probable glutathione peroxidase 2
- Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic
- Probable glutathione peroxidase 8
- Probable glutathione peroxidase 3, mitochondrial
- Probable glutathione peroxidase 4
Sequence:
MVLKVYGPHFASPKRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAHLPFTDYLVGPIGKAYMIKDRKHVSAWWDDISSRPAWKETVAKYSFPA
Protein: Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1) (Q9JJY4)
Organism: Mus musculus (Mouse)
Function: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs) (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9UHI6}. Nucleus, gem {ECO:0000250|UniProtKB:Q9UHI6}. Note=Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems). {ECO:0000250|UniProtKB:Q9UHI6}.
Interaction partners:
- Gem-associated protein 2
- Gem
- Gem-associated protein 5
- Gem-associated protein 7
- Survival motor neuron protein
- Serine-threonine kinase receptor-associated protein
- Protein argonaute-2
- Gem-associated protein 8
- Gem-associated protein 6
- Small nuclear ribonucleoprotein Sm D1
Sequence:
MAAAAFEVPAALTTSESTMAAERAAAPVQAVEPTPASPWTQRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEVLANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKVPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCNINLLPLPDPIPPGLMEECLNWDVEVKAAMHTYSSPTVATQSPKKQVQKLERAFQSQRTPGNQTPSPRNTSASALSARPKHSKPKLPVKSHSECGVLEKAAPPQESGCPAQLEEQVKNSVQTSVEDSSSNSQHQAKDSSPGSLPKIPCLSSFKVHQPSTLTFAELVDDYEHYIKEGLEKPVEIIRHYTGPEAQTGNPQNGFVRNRVSEDRAQMLVSSSQSGDSESDSDSCSSRTSSQSKGNKSYLEGSSDTQLKDTECTPVGGPLSLEQVQNGNDTPTQVEYQEAPETQVKARHKEGANQRSKQSRRNPARRSSYRVQSEPQEESWYDCHRETTASFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWNAQRHPSWMAAYHMNTVYLQEMMRGNQ
Protein: Sporozoite protein essential for cell traversal (Q8IDR4)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKMKIPICFLIILVLLKCVLSYNLNNDLSKNNNFSLNTYVRKDDVEDDSKNEIVDNIQKMVDDFSDDIGFVKTSMREVLLDTEASLEEVSDHVVQNISKYSLTIEEKLNLFDGLLEEFIENNKGLISNLSKRQQKLKGDKIKKVCDLILKKLKKLENVNKLIKYKIILKYGNKDNKKEMIQTLKNEEGLSDDFKNNLSNYETEQNNDDIKEIELVNFISTNYDKFVVNLEDLNKELLKDLNMALS
Protein: Calmodulin-binding transcription activator CBT (CaM-binding transcription factor) (OsCBT) (Q7XHR2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription activator that binds calmodulin in a calcium-dependent manner in vitro. Binds to the DNA consensus sequence 5'-T[AC]CG[CT]GT[GT][GT][GT][GT]T[GT]CG-3'.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00767, ECO:0000269|PubMed:16192280}.
Interaction partners:
Sequence:
MAGAGGWDPLVGSEIHGFLTYPDLNYEKLVAEAAARWFRPNEIYAILANHARFKIHAQPVDKPVSGTVVLYDRKVVRNFRKDGHNWKKKKDGRTVQEAHEKLKIGNEERVHVYYARGEDDPNFFRRCYWLLDKDLERIVLVHYRQTAEENAMAPPNPEPEVADVPTVNLIHYTSPLTSADSTSGHTELSLPEEINSHGGISASSETGNHDSSLEEFWANLLESSIKNDPKVVTSACGGSFVSSQQINNGPKNSGNIVNTSMASNAIPALNVVSETYATNHGLNQVNANHFGALKHQGDQTQSLLASDVDSQSDQFISSSVKSPMDGNTSIPNEVPARQNSLGLWKYLDDDSPGLGDNPSSVPQSFCPVTNERLLEINEISPEWAYSTETTKVVVIGNFYEQYKHLAGSAMFGVFGEQCVAGDIVQTGVYRFMVGPHTPGKVDFYLTLDGKTPISEICSFTYHVMHGSSLEARLPPSEDDYKRTNLKMQMRLARLLFATNKKKIAPKLLVEGTKVANLMSALPEKEWMDLWNILSDPEGTYVPVTESLLELVLRNRLQEWLVEMVMEGHKSTGRDDLGQGAIHLCSFLGYTWAIRLFSLSGFSLDFRDSSGWTALHWAAYHGRERMVATLLSAGANPSLVTDPTPESPAGLTAADLAARQGYDGLAAYLAEKGLTAHFEAMSLSKDTEQSPSKTRLTKLQSEKFEHLSEQELCLKESLAAYRNAADAASNIQAALRERTLKLQTKAIQLANPEIEASEIVAAMKIQHAFRNYNRKKAMRAAARIQSHFRTWKMRRNFINMRRQVIRIQAAYRGHQVRRQYRKVIWSVGIVEKAILRWRKKRKGLRGIASGMPVVMTVDAEAEPASTAEEDFFQAGRQQAEDRFNRSVVRVQALFRSYKAQQEYRRMKIAHEEAKIEFSEGQLGAACRS
Protein: Tectonic-3 (Q6NUS6)
Organism: Homo sapiens (Human)
Function: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). May be involved in apoptosis regulation. Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Tectonic-1
- Coiled-coil and C2 domain-containing protein 2A
- B9 domain-containing protein 1
- Tectonic-2
- Transmembrane protein 216
- Meckelin
- B9 domain-containing protein 2
- Tectonic-like complex member MKS1
- Jouberin
- Centrosomal protein of 290 kDa
Sequence:
MRTPQLALLQVFFLVFPDGVRPQPSSSPSGAVPTSLELQRGTDGGTLQSPSEATATRPAVPGLPTVVPTLVTPSAPGNRTVDLFPVLPICVCDLTPGACDINCCCDRDCYLLHPRTVFSFCLPGSVRSSSWVCVDNSVIFRSNSPFPSRVFMDSNGIRQFCVHVNNSNLNYFQKLQKVNATNFQALAAEFGGESFTSTFQTQSPPSFYRAGDPILTYFPKWSVISLLRQPAGVGAGGLCAESNPAGFLESKSTTCTRFFKNLASSCTLDSALNAASYYNFTVLKVPRSMTDPQNMEFQVPVILTSQANAPLLAGNTCQNVVSQVTYEIETNGTFGIQKVSVSLGQTNLTVEPGASLQQHFILRFRAFQQSTAASLTSPRSGNPGYIVGKPLLALTDDISYSMTLLQSQGNGSCSVKRHEVQFGVNAISGCKLRLKKADCSHLQQEIYQTLHGRPRPEYVAIFGNADPAQKGGWTRILNRHCSISAINCTSCCLIPVSLEIQVLWAYVGLLSNPQAHVSGVRFLYQCQSIQDSQQVTEVSLTTLVNFVDITQKPQPPRGQPKMDWKWPFDFFPFKVAFSRGVFSQKCSVSPILILCLLLLGVLNLETM
Protein: B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b) (P15530)
Organism: Mus musculus (Mouse)
Function: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10587346, ECO:0000269|PubMed:11238609, ECO:0000269|PubMed:15661879}; Single-pass type I membrane protein {ECO:0000269|PubMed:10587346, ECO:0000269|PubMed:11238609, ECO:0000269|PubMed:15661879}. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Interaction partners:
- Tyrosine-protein kinase SYK
- B-cell antigen receptor complex-associated protein alpha chain
- Immunoglobulin lambda-like polypeptide 1
- Tyrosine-protein kinase Lyn
- C-X-C motif chemokine 9
- B-lymphocyte antigen CD19
- B-cell receptor CD22
- Tyrosine-protein kinase BTK
- B-cell linker protein
- B-lymphocyte antigen CD20
Sequence:
MATLVLSSMPCHWLLFLLLLFSGEPVPAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYTNHSGALTWFRKRGSQQPQELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCKQKCDSANHNVTDSCGTELLVLGFSTLDQLKRRNTLKDGIILIQTLLIILFIIVPIFLLLDKDDGKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE
Protein: malate dehydrogenase (EC 1.1.1.37) (Q387X2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Citrate synthase
- Aspartate aminotransferase
- aspartate transaminase
- fumarate hydratase
- phosphoenolpyruvate carboxykinase
- fumarate hydratase
- Malic enzyme
- Malic enzyme
- Malate dehydrogenase
- NAD-specific glutamate dehydrogenase
Sequence:
MVSVAVIGAAGGIGQSLSLLLLRQLPYGSTLSLYDVAGAPGVAADLSHVDRAGVTVKYAAGKLPPVKRDPALAELARGVDVFVIVAGVPRKPGMSRDDLFNVNAGIIMDLVLTCGSSSPQACFCVVTNPVNSTVPIAAEALKKLGIYNKNKLLGVTLLDGLRATRFINNARHPLAVASVPVVGGHSDVTIVPLFSQLPGPLPEEGELTQIRKRVQVAGTEVVKAKAGRGSATLSMAEAGARFAMFVVNAITGQSSPMVYAYVDTDGTQNCSFLAIPVVLGKNGIEKRLPIGPMNAVEKEMLKQSISVVKANIEKGMNFARSKL
Protein: Protein Wnt (A0A2R8S090)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
Interaction partners:
Sequence:
MAAGLVHAVTRSCSAGNMTECSCDTSLLGSGSPTEGWHWGGCSDDIAFGTSFSRRFIDSAAKNTSTRGEEALLIMKQHNSEAGRQAVAKTMLTDCRCHGVSGSCAVKTCWRTMAAFERVGAYLKDRYETSVHVVDRSKRKVRRKDKEQRHVPITKDELIFFNKSPNYCLEDRRLGVTGTRGRKCNRTSAGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMNDMHTCK
Protein: Mutator family transposase (O05912)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MDAAQVIEPAHAGQDVDEAAVAARELSGAERALVGDLVRQARAEGVALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSRNKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKGLTTGEIAAHFADVYGVSVSKDTISRITDRVIEEMQAWWSRPLEKVYAAVFIDAIMVKIRDGQVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKFWLAVLTDLRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRNTFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAEKWGKPYPAITRLWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQSALKTLYLVTRSLDPKGTGQTKWAVRWKPALNALAITFADRMPAAEER
Protein: High mobility group AT-hook 2 (A0A8I6GCP7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSARGEGAGQPSTSAQGQPATPAPQKRGRGRPRKQPQEPTCEPSPKRPRGRPKGSKNKSPSKAAQKVRVSNASFSNVINDFHVRFFHSKSTNLRTGLSWVTQDIFPVFVIWVLSPLPLPGLRLSLKAS
Protein: Probable enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (P34559)
Organism: Caenorhabditis elegans
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Probable 3-hydroxyacyl-CoA dehydrogenase B0272.3
- 3-hydroxyacyl-CoA dehydrogenase
- Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1
- 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
- 3-hydroxyacyl-CoA dehydrogenase type-2
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Isobutyryl-CoA dehydrogenase, mitochondrial
- Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
- Short/branched chain specific acyl-CoA dehydrogenase
Sequence:
MMRFSSMLVRNAKLCANVNQMQVAAFSSKAPEMIKIEKVGEKQNVALIKLNRPKALNALCAQLMTELADALEVLDTDKSVGAIVITGSERAFAAGADIKEMTNNEFATTFSGSFLSNWTAVSDVKKPVIAAVNGFALGGGNELAMMCDIIYAGEKARFGQPEINIGTIPGAGGTQRWARAAGKSFAMEVCLTGNHVTAQEAKEHGIVSKIFPADQVVGEAVKLGEKIADQSPLIVQMAKEAVNKAYELTLQEGLHFERRLFHATFATKDRKEGMTAFAEKRKPQWESK
Protein: trypsin (EC 3.4.21.4) (Q9VQA0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- trypsin
- Peptidase S1 domain-containing protein
- Peptidase S1 domain-containing protein
- trypsin
- trypsin
Sequence:
MFSKCFHLLLAVHLLISPVVPVLLEPSERIIGGSSMDITDVPWQVSLQYYGEHFCGGSIYSKTIIITAAHCIKEGERSIRAGSSLHDSGGVVVGVEAYIIHPQFDKHNMENDVAVLKLSSPLSFSDSIQTIPLAETDPPTSSSALATGWGRGNFLIRPRQLQGVEILIRPLIVCKLKYGNGVFNEDICAGRMGKGGCYGDSGGPLVFNGQLVGITSRTGNIVCLGSSLYASVARYRNWILSAIDVLHFQAPATNV
Protein: Small ribosomal subunit protein bS6 (30S ribosomal protein S6) (P56013)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Binds together with S18 to 16S ribosomal RNA.
Interaction partners:
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein bS18
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein bS16
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS2
Sequence:
MRHYETMFILKPTLVEEEIKSKIEFYKEVITKHHGVIETSLDMGMRNLAYEIKKHKRGYYYVAYFKAEPSMIVELERLYRINEDVLRFIVIKYESKKEVEAWHALVDRANKKPSHAKEKHEKTEHTHSHHTEEAESVGSHSE
Protein: Uncharacterized protein (Q383Z7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MYRSVGEAVGRTPKQDAPPYDPSLWEGKDCAFITVLKEAHERQQRQERHRDAQHGGVDEAGLAAPHTSHIQLTYTPTSWWERLMLKLFPRYYALRVMANSDISRLSNEELVMRMHLALQAGDGDFSALIAQELARRRVYLYREEVTTVNTTPGGAAVRRNNYRGMGSSDEGVGIMRARYSDSAVKQGAVSHVADSSFTVPEFLLRRPSYGG
Protein: Thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) (TRH-degrading ectoenzyme) (EC 3.4.19.6) (Pyroglutamyl-peptidase II) (PAP-II) (TRH-specific aminopeptidase) (Thyroliberinase) (Q9UKU6)
Organism: Homo sapiens (Human)
Function: Specific inactivation of TRH after its release.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- Pro-thyrotropin-releasing hormone
Sequence:
MALDGELGEQEEEKKKKKKKKRKKKKEEEEEEEGAEKSSSPFAAAMGEDDAALRAGSRGLSDPWADSVGVRPRTTERHIAVHKRLVLAFAVSLVALLAVTMLAVLLSLRFDECGASATPGADGGPSGFPERGGNGSLPGSARRNHHAGGDSWQPEAGGVASPGTTSAQPPSEEEREPWEPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHASRVAVEKVQLAEDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRIIITQQHFIYDISAKTKALKLQNNSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYIKLGWPKNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKNYDGVAAASFSRAVETVEANVRWKMLYQDELFQWLGKALRH
Protein: Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (CBP-interacting protein 4) (Nucleoporin Nup93) (Q8BJ71)
Organism: Mus musculus (Mouse)
Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC (By similarity). During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (By similarity).
Subcellular location: Nucleus membrane {ECO:0000250|UniProtKB:Q66HC5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q66HC5}. Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q8N1F7}. Nucleus envelope {ECO:0000269|PubMed:26878725}. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore. {ECO:0000250}.
Interaction partners:
- Nuclear pore complex protein Nup155
- Nucleoporin 205
- Nuclear pore complex protein Nup107
- Nucleoporin NUP35
- Nucleoporin NUP188
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein Nup54
- Nuclear pore complex protein Nup214
- E3 SUMO-protein ligase RanBP2
- Nucleoporin SEH1
Sequence:
MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYIGDVNPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCASVAELDDKSISDMWAMVKQMTDVVLTPATDALKSRSSVEVRMDFVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSATRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN
Protein: AT5g47860/MCA23_20 (Gut esterase (DUF1350)) (Q9FIJ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable ribosome biogenesis protein RLP24
- Ribosome production factor 2 homolog
- Pescadillo homolog
- Ribosome biogenesis protein BOP1 homolog
- AT5g04600/T32M21_200
- Protein MAK16 homolog
- Ribosome biogenesis protein WDR12 homolog
- Nucleolar complex-associated protein 3
- 60S ribosome subunit biogenesis protein NIP7 homolog
- Probable rRNA-processing protein EBP2 homolog
Sequence:
MATCSLLPPPSFSPRRRFCSFSHNRRSLPSIFSFNKERVSRRVFCSSKENDINRDRNQSTGIQVYGEIERLLTETVKNSQSSSGGSSDWSEVEGAWVLKPRNSKPKMVVHFIGGIFVGAAPQLTYRLFLERLAEKDVLVIATPYASGFDHFNIADEVQFKYDRCCRSLQEEVQDLPSFGIGHSLGSVIHLLIGSRYAVQRNGNVFMAFNNKEASLAIPLFSPVLVPMAQSLGPLLSQVATSPTIRLGAEMTRKQLETLSPPIMKQILPLVEQLPPLYMDLVKGREDFVPKPEETRRLIRSYYGISRNLLIKFEDDSIDETSILAQVLGVESSISSKLDMSIRTLPGDHGLPLQQALPDVPPGMAEAVNRGSEFLANIAVGTPWESMAKEVGGSLGMDSKILRADMSKDLAQLVDAITSWMISNMGPKLLRP
Protein: RE34633p (Q8SYT6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSVSHNYDQMSQPTNTTTTQTKASKRPSRFNSKMPVVNSRLAELARITVLLTALLVSYASGLQTVGESADDNTICLYREYNTTYRKEIGAVWFASKDPCLVYSCAAGVAKDPQAHIVATQVDCNEFYCEVGSELRSVEGSCCGECVRTHCQHNHTLYAVGESWHNDADCTLIECGRLDNGQIVMNTYKRNCPALTEDCPASRLEERNCCPYCRPLQTARIEELQDNVAESTDDIWTAEWYRNHPCNRDCQVGAEPMTCRYKFVVEWYQTFSKACYDCPRNLTDCSRPHCVMGDGLERSITVVNRMMPGPAIEVCEGDEIVVDVKNHLLGESTSIHWHGLHQKKTPYMDGVPHITQCPITPHATFRYSFPADLSGTHFWHSHTGMQRGDGVFSALIIRKPKTAEPHGGLYDFDLSEHVMIVQDWIHDTGASIFSYHHHSRGDNKPHNLLVNGKGRYYNRIWAEAKQAHRRAEERTTQPVEPLPKSQVDFVQTLPRQARLAKTNTTKLFPVNSRQKRGNLNEIPLELVPHQIYTVRRGFRYRFRIINAEYLNCPIVVSIDGHNLTAINSDGFDIEAMDVGSIVTYSGERFDFVLNANLEVGNYWIRLKGLMDCSEVFTSAFQVAILRYEGAPDEEPTAELSYGHKAEGIELNVMNRGPGYPDTKTVAEMRALPIYDHVSGIDHDTLKPEADYKFFIYYDFYTKNNPDFHDKDLYAMDMEMTQQNRLYTPQLNHITLNFPSLALLPSRSQLKDSDFCNETSLMDQGIDCRQEFCKCHHVLQVPLGAVVEMIIVDEGFQYYANHPFHLHGNAFRVMGLERLGENVTVEMIKQLDQFNLLKRNLDNPPVKDTVTIPDGGYTIIRFEASNPGYWLFHCHIEFHAEIGMALVFKVGNDDQMVPVPENFPTCGDYNPDLRSDGGTTEDSGSSKPITATPPNTGGGGSGLEPTWITLMISSMLVKLYR
Protein: Nuclear pore complex glycoprotein p62 (O57397)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
Sequence:
MSGGFNFGQASSTGFSFGAPKTTAATAPATGFGMPSAAAPGGGFSFGTPSTPQAPVAAPQSSGLFAMPTQGSTNPTGGFSFGTPAQSSTPAGGGFSFGTPIAKLNLGTPVASQPALTGLTMGMATPSSGTGFGLGGGLAAQTTAAPAGGGFSFGTAGGLGAPVAQTQPQTQPAAAGGLSLGTPAEATQIMGGGFSFGAAKVQATTAPAPTVTVGGGFSFGNSTPASLSLGTQPTSLTLNSVASTAVPTTTQVGGFAFGVKPSATPAPTATAPATQASLGSSLFAVPASTAAPATAAITGFLGAAPTSAVPAATSTAGSTLGFMLKPLGAVTATTTAPVGTAAPTTTTGFSLAMKPAGAIGIGVTAPITGVATTIATVTASAPPVMSYMQLEGLINKWSLELEDQERHFLQQATQVNAWDRTLVENGEKITSLHREMEKVKLDQRRLDQELDFILSQQKELEDLLSPLEESVKEQSGTIYMQNADEERERTYKLAENVDAQLKRMSQDLKEIIEHLNTSSGPADNSDPLQQICKILNAHMDSLQWIDQNSVLLQRRVEDVSKLCDNRRKEQEKTFRITFH
Protein: Sensor protein KdpD (EC 2.7.13.3) (P21865)
Organism: Escherichia coli (strain K12)
Function: Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates KdpE in response to environmental signals.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:1532388}; Multi-pass membrane protein {ECO:0000269|PubMed:1532388}.
Interaction partners:
- KDP operon transcriptional regulatory protein KdpE
- Potassium-transporting ATPase KdpC subunit
- Potassium-transporting ATPase ATP-binding subunit
- Potassium-transporting ATPase potassium-binding subunit
- Potassium-transporting ATPase KdpF subunit
- Nitrogen regulatory protein
- Low affinity potassium transport system protein Kup
- Universal stress protein C
- Trk system potassium uptake protein TrkA
- Putative electron transfer flavoprotein subunit YgcQ
Sequence:
MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAEAQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPLKRQAYRGRHISEFDLDAALARRPALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGIQVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIALRELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASRLGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYAREHNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDNRSFKDKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVVATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYREQRTRHLYEMSKALAVGRSPQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQGMTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMIPEQQRLLETFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVLFGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLTLEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIVDVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM
Protein: Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.7) (Q9VE09)
Organism: Drosophila melanogaster (Fruit fly)
Function: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03150}.
Interaction partners:
- Glutamyl-tRNA
- Probable glutamine--tRNA ligase
- Glutamyl-tRNA
- Asparagine--tRNA ligase, cytoplasmic
- asparagine--tRNA ligase
- Bifunctional glutamate/proline--tRNA ligase
- Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial
- Grain, isoform C
- Serine/threonine-protein kinase RIO2
- Aspartate--tRNA ligase, cytoplasmic
Sequence:
MRRHLQWSIKQLTASYSDGQLSPRRVTEDALQDALRWKTLNAFVRLTPEQAGQQAQDAEQRYKLRQPISDLDGVTIAIKDNFCTKDVHTTCASRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSLYGPTKNIWSEDLNKDHWRIAGGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASYCGVVGLKPTYGLVSRHGLIPLVNSMDVPGIFARSVSDCVAVLNTVAGPDKLDSTTIRQPFTRLHLPEVGQIDLSTVRIGIPKEYHCHGLSAEVLETWSKVADLLECSGASVRQVSLPNTAASIFVYTILNQCEVASNMARYDGIEYGHRATDERSTEQLYALSRAEGFNDVVKTRILTGNFLLLKKNYDHYFEKALRVRRLIAEDFARVFDSSAKEERVDILLTPTTLTEAPLYKDFASLTNRDQCAVQDFCTQPANMAGIPAVSIPIRLSQAGLPLSLQLMSNSLNEQLLLTVARWIEAQVEFDSLEHSQQYKASL
Protein: Tripartite motif containing 73 (I3L0H3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEFIWFHSMASR