wanglab/gogpt-training-data huggingface dataset:
Protein: Tomosyn (Q49HI2)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MRILVVRHGLPEDPRCFAYDPVQRLIAIGTGRGHIRIIGDAGVDYLLKHESGEPVLHMQFLVNEGGLITSCGTDSIHLWNYRQKTAEIVHTVQLSKESVSCIHLPVAGKWLFIGTDKGNVYFLCLNSFLLSPYVINWNKAIDLSCRVHPGPVRQLAVSPAENTKLLIVYDKGIVVQWNLGTREVDRYPLDPPIKSVNWHFDGRQILTGNVDGSISLYNHKKSTEAIQRTTPHGSGPCRPIQQVEWKHMSETESIIMFSGGMPTDDGLPMPALTILKGGKSATVLEMDWPIIQFIPLNQNIWNSIPQCPHSVAVLLKHDFMVLDLNQNGHPVIESPHAMNIHESPVTCMAYYSDCPLDLIGALTLVGTKQRNKEFSARSWPVTGGLGRECATGHQELVVTGHKDGSLKFWQETGEHLQILYKLKSSSHFERLEEMETSDKVSHAVKYIELCLESRQLLVAGISGQVTLFRFTKQVSVIRVFQIDEFENDDTLIYNTDTGNYTLRSTRNSLTPSSNGFLHPGEMPTRPKSAANSSNKSGGMMGLFRRNTAELAATIRERYQGNRSESATTDRPDVEHRGETPPPTPNEGNKVQKAGRSHSVKGSFIRRFAKSSSSKEKKEVKIEVDNQSNSGIERSRSFHSHISEEGDSQRESPSSGRQLNTSSPSTSSQSLERSMSTQPQESITSLSFIHSYSKKNDSKMSPCLWVGTSAGASLALNLILPEDRFTSTIVVAPSGTVVRLKGQVISQSFMDNTFCIISPASESYKEAAKEQSATSPDRSLLNRVNTKASLAPQYSSSIDSNDEISQILIVAAENEVKVVALPTFSQLYVQKFDEIPLVKATPTHIRGYPCLMCLSAAGQIIMLSLPSLRILQTSTIFPHSVEIDDPLCQKTAFSDHGLGVYMASQTEMEKYTMCSEIAEQTGESLGELFVPCEMPEQPKNNSFLKGVSSIFGGTPRNDPNDIDAILSENMGVKNSSGVNPMRSVARTIPGPSVQMDRAQAGGVSAGQAAAMALQNLNERTEKLNATVDATENLKNNAMSLSSRTGKLVEKYEKKKWYNF
Protein: Uncharacterized protein (Q57YN8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- BILBO1 N-terminal domain-containing protein
- Uncharacterized protein
Sequence:
MKEKKEVNSSRKGWMPPRGRLTATSRGPVPPPPSRTPTRCSSICRVPKDRFRGPPAVAATTTPRSRESGSACHCVPLRRKNASNDNAFATRRTAIVDEKTPSAQKPVQPYVADERIEKMRRSMNGTNRRSCSESMRDAEPVSFHMAPYPRVPFVRQSSNRCESTPSSYRTRVSTAQQCSFGGHAARPTVAGTELLPRMPHLQGTHRTSKERGRATLERFLQTQPTDAQNEVRDLMKEYKGREEELCDALNIAFGESAGGVAMGLSTSTSGGATPVPRRYDIPQPYRGPTPLKQEVTDTSILNTSPKLHSRSAMSATVRVNSEANPIASSASPYRHGCSPRRTQPSRNRVNPRDGVYSQPPSGMISACTPISSPSRGRGTGWAKSLYNELREEGSLSPYLRYLPSDVSGGEWDKPDVGDVLCFQAKEPQRRRVLTSPVPDELLIK
Protein: Meiotically up-regulated gene 1 protein (Q9USP4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for correct meiotic chromosome segregation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Meiotically up-regulated gene 5 protein
- Microtubule-associated protein ssm4
- Centractin
- Meiotic coiled-coil protein 5
- Actin-like protein arp10
Sequence:
MKEMINLDSSSEPSIVTKQFSVEECLSKLKEQHCYVPMRTIGRLRLRKSSDQTEKKCWKEKLMKIRSELEELWEQSMMYEEQKELTQLGEMLDRLWDKHINSEGSKSETISDTAISGNDDTMEKRLEQFSDDTLQDTLETEKNLNSKTSESLKSPTLSYPFDLDSLDKRIFKLESKIGYADEPLSELLNKCMEKLEIVEQDPQFWQSRIESWKQLLAKDFLKHHERNLCSIEKQTTLKNSSLKELCTEEDIVIMLEICSSQLPFVEQYMPILPLLLERLKSLQNMHTDAAEAISSWQGSKDVMMTMQSELNEWKNTVERLDHSKFYTQSVEEMRRLSDTVTQLEKRVLKLQ
Protein: Vacuolar protein sorting 11 (Yeast homolog) variant (Q53FX3)
Organism: Homo sapiens (Human)
Subcellular location: Late endosome membrane {ECO:0000256|ARBA:ARBA00004492}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004492}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004492}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004630}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004630}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004630}.
Interaction partners:
Sequence:
MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLQVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQTGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTLIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT
Protein: Probable sulfate permease C320.05 (O59782)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Possible sulfate transporter.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- GTP-binding protein ypt1
- Putative glutamine amidotransferase PB2B2.05
- Protein isd11
Sequence:
MSSPSENHLLGPKTSFIDNRTSTSRPLHEIPSYQSLARRSSTWKRANIPQQKPSLVRRINYYIPVLHWLPNYSLRNIIWDVLAGCSTACLSVPIALSFAQTFLGVPPIYILTGTAIGPILYCLFTACPLISIGPEAGMCLLIAENIHQRVLSKADVPQETAILVTGLIAFIAGIINLAAGLFRLGFLDALVSPVLLRGCILSISMIIMINQGSVFFGFSGVKYKGSDFPIDKLMFLIRNMSKANIYTTILSCITISLLIGCRNLKSKLSAKYPRIVSIPDAVIILLLGSFLSKKFDWHSNYGIAILGEIKTTILLPKLPLPEKNKLHFITQSLQTGVMCSFLAFIDTVIAVKAISLQTNNLIRSNRELISLGAANIGSSLFCGLPICGGYLRTKCNIMSGARTQVATIACSVLILLATFFIMPVFSTVPTCMLASMVVSLGVSLFADAAVEIFKLARIRVWWELGIIFSIATCTMMFGLETGIIFGLSITVMQIIRHSTRSRIMFRSPTSNGTAEFILEDAASTLSHRTNPSSTAVESAPRILVVRIPEPLFFANVSQLEDRLNRLEKYGHPRMHPGETPYRRIEDIEVVVFDMVGVSSIDSSALFAFQRILKEYVEHQVEVHLVSLDPQVLHIFEKHGLLDLIGGYDHVQDSIKKVDALCDIELGV
Protein: Protein CHROMATIN REMODELING 8 (AtCHR8) (AtCSB) (EC 3.6.4.-) (Q9ZV43)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential factor involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q03468, ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- DNA-directed RNA polymerase II subunit 4
- WD repeat-containing protein ATCSA-1
- DNA repair protein UVH3
- DNA repair protein RAD51 homolog 1
- Transducin/WD40 repeat-like superfamily protein
- DNA-directed RNA polymerases II, IV and V subunit 11
- DNA-directed RNA polymerases II, IV and V subunit 9A
- DNA-directed RNA polymerases II, IV and V subunit 9B
- DNA damage-binding protein 1a
- DNA-directed RNA polymerases IV and V subunit 3B
Sequence:
MEEDEDQFLLSSLGVTSANPEDLEQKILDEATKKPDNDEGGSVEEKSTQLEGTNLLSSSQNELLNKLRAVKFEIDAVASTVENVDEIAAEKGLKKDDESDLQGLHSGSALQHALATDRLRSLKKRKIQLEKELTGLHGQSASSSADHGNLLRDLVKEKPSLKRKLKEIRKPSRRDGKKVKVVSFREDTDFDAVFDGASAGFVETERDELVRKGILTPFHKLDGFERRLQQPGPSNSRNLPEGDDENEDSSIIDRAVQSMSLAAKARPTTKLLDAEDLPKLEPPTAPFRRLRKLYKTPNSPDNEAKKRKAGKKSKKTRPLPEKKWRKRISREDSSLQGSGDGRRILTTSSCEEEELDDFDDADDNERSSVQLEGGLNIPECIFRKLFDYQRVGVQWLWELHCQRAGGIIGDEMGLGKTIQVLSFLGSLHFSKMYKPSIIICPVTLLRQWRREAQKWYPDFHVEILHDSAQDSGHGKGQGKASESDYDSESSVDSDHEPKSKNTKKWDSLLNRVLNSESGLLITTYEQLRLQGEKLLNIEWGYAVLDEGHRIRNPNSDITLVCKQLQTVHRIIMTGAPIQNKLTELWSLFDFVFPGKLGVLPVFEAEFSVPITVGGYANASPLQVSTAYRCAVVLRDLIMPYLLRRMKADVNAHLTKKTEHVLFCSLTVEQRSTYRAFLASSEVEQIFDGNRNSLYGIDVMRKICNHPDLLEREHSHQNPDYGNPERSGKMKVVAEVLKVWKQQGHRVLLFSQTQQMLDILESFLVANEYSYRRMDGLTPVKQRMALIDEFNNSEDMFVFVLTTKVGGLGTNLTGANRVIIFDPDWNPSNDMQARERAWRIGQKKDVTVYRLITRGTIEEKVYHRQIYKHFLTNKILKNPQQRRFFKARDMKDLFILKDDGDSNASTETSNIFSQLAEEINIVGVQSDKKPESDTQLALHKTAEGSSEQTDVEMTDKTGEAMDEETNILKSLFDAHGIHSAVNHDAIMNANDEEEKMRLEHQASQVAQRAAEALRQSRMLRSRESISVPTWTGRSGCAGAPSSVRRRFGSTVNSRLTQTGDKPSAIKNGISAGLSSGKAPSSAELLNRIRGSREQAIGVGLEQPQSSFPSSSGSSSRVGSLQPEVLIRKICSFVQQKGGSADTTSIVNHFRDIVSFNDKQLFKNLLKEIATLEKDQNRSFWVLKSEYKD
Protein: Refilin-B (Regulator of filamin protein B) (RefilinB) (Q5SVD0)
Organism: Mus musculus (Mouse)
Function: Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in the formation of cartilaginous skeletal elements.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21709252, ECO:0000269|PubMed:24436304}. Note=Colocalizes with FLNA along actin bundle-like structures. {ECO:0000269|PubMed:24436304}.
Interaction partners:
Sequence:
MVGRLSLQDVPELVDTKKKGDGVLDSPDSGLPPSPSPSHWGLAATAGGGGERAPVAGTLEPDAAVTPIVPNPASLTHSLAAICSPRLCPLSFGEGVEFDPLPPKEIKYTSSVKYDSERHFIDDVQMPLGLVVASCSQTVTCIPNCTWRNYKAEVRFEPRPKPARFLSTTIVYPKYPKTVYTTTLDYNCHKKLRRFLSSVELEATEFLGSDGLADEC
Protein: Smooth, isoform O (A0A0B4K7B0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPYNGASNGSGASGAGGGGATIVVTEGPQNKKIRTGVQQPGENDVHMHARSTPQQNQQQALMNKSNDDLRRKRPETTRPNHILLFTIINPFYPITVDVLHKICHPHGQVLRIVIFKKNGVQAMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNVYKNEPDTSWDYTLSTGEILPSKSLFSIPENVVMLESQPPLLGPGAAFPPFGAPEYHTTTPENWKGAAIHPTGLMKEPAGVVPGRNAPVAFTPQGQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVINPFLLPDHSPSFKEYTGSKNNRFLSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVPATSVRLFPLKTERSSSGLIEFSNISQAVLAIMKCNHLPIEGTKFPFIMKLCFSSSKSMNGAWNNAASEGMIEKENEVDTKVDIYN
Protein: Uncharacterized protein (Q388Q4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGVEIPLPTNSAPPQGQDGSSKATPNSLANSSKTLVGSLRPLRSKGTLMPGKANNGEKVCESPPLPRHSIPLLPGHIKPKMCGPPSPEDGGQQPKFLGRMQKRNIVHLDHRLNAICPRAPPDSCGVDDKGSEKLICRRRPADKAQFHKAIDLLNSMIEADARKFDMREWVIRHAEGRGGAQLSKEQLQPVWILVGSDFVLAVDLNGSAQHRNYSDVAALQLEQFPPEGAIVFPLEGVLKTGELRLPQTSTGVKAMNVLLHGESRWGAPIGVLFMSPSDQSSIIQDICQSYLPSFLRSAYPMGVQLRGEWISTVFSSEVGEFRVAELPQKFRDGLHSSMAAQGTSGTSSLTGEGYRISDVEVVQSLEKLDSTELHGERKTNVEMGSSPSFNLKNQQQEMLSTTSQASKPPPTNPPWEGGERGPLFSGRLHTLQSVPPKGSPTTFCHGVLLLTARGPLELLPESTTSHVRIKDVKLSFLRSGVGRCMRLTQESVRFMYVPSGPVLSDNHVVDTRYAVLRLQTHK
Protein: Lymphocyte cytosolic protein 1 (A0A8I6G984)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSSFSGLSPKAVKMARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGKISFDEFIKVFHGLKSTEVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFNAVGDGIVLCKMVNLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCTKITNFSTDIKDSKAYYHLLEQVAPRGDEEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNKYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPGVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNRPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDIGGGQKVNDDIIVNWVNTTLKEAQKSSSITSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV
Protein: Kallikrein-15 (EC 3.4.21.-) (ACO protease) (Q9H2R5)
Organism: Homo sapiens (Human)
Function: Protease whose physiological substrate is not yet known.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Aconitate hydratase, mitochondrial
- Cytoplasmic aconitate hydratase
Sequence:
MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN
Protein: RNA-binding protein mde7 (Mei4-dependent protein 7) (O59784)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Meiotically up-regulated gene 28 protein
- Meiotically up-regulated gene 24 protein
- mRNA export factor crp79
- Large ribosomal subunit protein uL1m
- Meiotically up-regulated gene 60 protein
- Uncharacterized family 31 glucosidase C1039.11c
- Meiotic PUF family protein 1
- Uncharacterized protein PB8E5.10
- Protein phosphatase PP2A regulatory subunit B
- Start control protein cdc10
Sequence:
MSQLYALNGQPLAGKSDDLANKLAAFGLSQPNHSSLSEQQSTNSLLHGSGAFNKPPLSRNSTTNPLNLLYTQTQQPARSTTPFLLNPVGSSPGKLPVPSRNNSYLQGTAESNSGNFANNSISNNCWNSAYNSNSFEGTGSSPNFPPQNQFLSDSRSSIATLNAIPSLDQSVLLNPNLRARTPSLVPEHYFDDTDKSVHSKSSSGSNSLSEASNDDLESSIIQIVGGLPDDFDDRELSGIFTFCEGYDFSKIESENGHRKAIVYFRNAIAALKAKNMLNASSTNNFTIIQRDVVRQQENEYHKGIPPLTTPSLYSQRLSNNYDSTTPGFPRFSPANFDSVINKDVTSESRMSTSYPAVLEAFKSFNPIKAPKAEYLNQSRASMGNPSPSNWNNRLLQPSSKEQAVYSFQTQKNSKGLQFTSNELTNPTAKYSQLPNNIANIGESNSLSNQPNNFAQTSFDYQPNHPNAISPKAKFSLPSRPSYHKDNSFISKQAIDKSNPFEEALRLERTSPVKELPAIRPRTIPLNGVAPYESELRPPPKWKPMPDLKVVRSRPSLKQRPLRSAEYVRVCELKCLQEEEFDNKVLLEQVESNVQTDHNSPCNTIYVGNLSNPDQEKKLRLAFSKEKGYRRLCFKIKGNSPMCFVEFEEVCHAAKAMEKMQGAALDDKIKGGIRLSYSKNPLGVRSTENLSTTASLFQQHGPPKKSTDCYSAKASAAVERKYHFQNMTPKPNGTNSVTTLNRTQTHSSEVNDLFDIFEFPSK
Protein: Probable cobalt/nickel-exporting P-type ATPase (EC 7.2.2.-) (Cation-transporting P-type ATPase CtpD) (P9WPT3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in heavy metal homeostasis. Probably exports nickel and cobalt ions out of the cell (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable thioredoxin TrxA
- Probable enoyl-CoA hydratase EchA12
- Conserved hypothetical proline and threonine rich protein
- Sphingomyelinase
- Ubiquitin-binding protein Rv1468c
- Conserved protein
- Thioredoxin
Sequence:
MTLTACEVTAAEAPFDRVSKTIPHPLSWGAALWSVVSVRWATVALLLFLAGLVAQLNGAPEAMWWTLYLACYLAGGWGSAWAGAQALRNKALDVDLLMIAAAVGAVAIGQIFDGALLIVIFATSGALDDIATRHTAESVKGLLDLAPDQAVVVQGDGSERVVAASELVVGDRVVVRPGDRIPADGAVLSGASDVDQRSITGESMPVAKARGDEVFAGTVNGSGVLHLVVTRDPSQTVVARIVELVADASATKAKTQLFIEKIEQRYSLGMVAATLALIVIPLMFGADLRPVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHGVLVKSAVVVERLADTSIVALDKTGTLTRGIPRLASVAPLDPNVVDARRLLQLAAAAEQSSEHPLGRAIVAEARRRGIAIPPAKDFRAVPGCGVHALVGNDFVEIASPQSYRGAPLAELAPLLSAGATAAIVLLDGVAIGVLGLTDQLRPDAVESVAAMAALTAAPPVLLTGDNGRAAWRVARNAGITDVRAALLPEQKVEVVRNLQAGGHQVLLVGDGVNDAPAMAAARAAVAMGAGADLTLQTADGVTIRDELHTIPTIIGLARQARRVVTVNLAIAATFIAVLVLWDLFGQLPLPLGVVGHEGSTVLVALNGMRLLTNRSWRAAASAAR
Protein: Catenin alpha-1 (A0A384MDY0)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, adherens junction {ECO:0000256|ARBA:ARBA00004536}. Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFKAMDSI
Protein: Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (E7EUI8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIRGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
Protein: Guanine nucleotide-binding protein subunit gamma (G3V6P8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004342, ECO:0000256|RuleBase:RU004973}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004342, ECO:0000256|RuleBase:RU004973}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004342, ECO:0000256|RuleBase:RU004973}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-4
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-12
- Muscarinic acetylcholine receptor M4
- Pituitary adenylate cyclase-activating polypeptide type I receptor
- Protein kinase C epsilon type
- Muscarinic acetylcholine receptor M1
- Guanine nucleotide-binding protein G
Sequence:
MSSKTASTNSTAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLMGIPTSENPFKDKKTCIIL
Protein: Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (Cyclophilin-like protein PPIL6) (Rotamase PPIL6) (Q8IXY8)
Organism: Homo sapiens (Human)
Function: Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
Interaction partners:
Sequence:
MARPQPCGPPHARCGSPSLPERPLQVKVVGLFSCPNFQIAKSAAENLKNNHPSKFEDPILVPLQEFAWHQYLQEKKRELKNETWEYSSSVISFVNGQFLGDALDLQKWAHEVWDIVDIKPSALYDALTEDFSAKFLRDTKHDFVFLDICIDSSPIGRLIFELYCDVCPKTCKNFQVLCTGKAGFSQRGIRLHYKNSIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTFEDENFSVPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVLKQLELVPTQNERPIHMCRITDSGDPYA
Protein: Neuropeptides B/W receptor type 1 (G-protein coupled receptor 7) (P48145)
Organism: Homo sapiens (Human)
Function: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Neuropeptide W
- Neuropeptide B
- Neuropeptides B/W receptor type 2
- Pro-neuropeptide Y
- Melanocortin receptor 4
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
Protein: Conserved protein (P71738)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
Sequence:
MQRFAENLVFTEAPKLVRHLQNTQETLRTIRQAVKITANIMTTAVPSPPAEIAAGRPVTSTSCPTAARARRLVYAPDLDGRADPGEIVWTWVAYEQDPTRGKDRPVLVVGRDRSVLLGLLVSSQERHAADRDWVGIGSGAWDYEGRESWVRLDRVLDVPEESIRREGAILEREVFDVVAARLRADYAWR
Protein: Molybdenum cofactor synthesis protein cinnamon [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] (P39205)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Interaction partners:
- Molybdopterin synthase catalytic subunit
- Molybdenum cofactor sulfurase
- Molybdenum cofactor biosynthesis protein 1
- Vesicular inhibitory amino acid transporter
- Gamma-aminobutyric acid receptor alpha-like
- Neurexin 1, isoform F
- Glycine--tRNA ligase
- Sulfite oxidase, mitochondrial
- Synapsin
- Adenylyltransferase and sulfurtransferase MOCS3
Sequence:
MESITFGVLTISDTCWQEPEKDTSGPILRQLIGETFANTQVIGNIVPDEKDIIQQELRKWIDREELRVILTTGGTGFAPRDVTPEATRQLLEKECPQLSMYITLESIKQTQYAALSRGLCGIAGNTLILNLPGSEKAVKECFQTISALLPHAVHLIGDDVSLVRKTHAEVQGSAQKSHICPHKTGTGTDSDRNSPYPMLPVQEVLSIIFNTVQKTANLNKILLEMNAPVNIPPFRASIKDGYAMKSTGFSGTKRVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLILSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASRKDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDFSLDSRPEFVRASVISKSGELYASVNGNQISSRLQSIVGADVLINLPARTSDRPLAKAGEIFPASVLRFDFISKYE
Protein: Enigma LIM domain protein-like (PDZ and LIM domain protein 7) (B5DGH1)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSIYCITLNGPAPWGFRLQGGKDFSMPLTVSRLTPGGKAAQAGVGVGDWVVSIGETNAEDMTHVEAQNKIRAAEELLTLTLSKAFHAGGDQKMDEKEDQPLYDHQNYQHEKHGLRVEGIPMFIPNDRSKKRLIEDTQDWQPRTGTTQSRSFRMLAQLTGTDYMQDPDDETMKRAREKFLTEIQSPRYARLRDWHHERSARALNIKS
Protein: HTH-type transcriptional repressor PurR (Pur regulon repressor) (Purine nucleotide synthesis repressor) (P0ACP7)
Organism: Escherichia coli (strain K12)
Function: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. In addition, it participates in the regulation or coregulation of genes involved in de novo pyrimidine nucleotide biosynthesis, salvage and uptake (pyrC, pyrD, carAB and codBA), and of several genes encoding enzymes necessary for nucleotide and polyamine biosynthesis (prsA, glyA, gcvTHP, speA, glnB). Binds to a 16-bp palindromic sequence located within the promoter region of pur regulon genes. The consensus binding sequence is 5'-ACGCAAACGTTTTCNT-3'. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
Interaction partners:
- Amidophosphoribosyltransferase
- Trp operon repressor
- Arginine repressor
- Signal peptidase I
- DNA-binding transcriptional dual regulator CRP
- Ribosomal protein uS12 methylthiotransferase RimO
- Large ribosomal subunit protein bL25
Sequence:
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
Protein: Histone H3-like centromeric protein cid (CENP-A homolog) (Centromere identifier protein) (Q9V6Q2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.
Subcellular location: Nucleus {ECO:0000269|PubMed:24703848}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:21080953}. Note=Localizes exclusively in the kinetochore domain of centromeres. Co-expressed with yemalpha. {ECO:0000269|PubMed:21080953}.
Interaction partners:
- Chromosome alignment defect 1
- Histone H4
- Centromeric protein-C, isoform A
- Histone H2A
- Chromatin assembly factor 1 p55 subunit
- Spc105-related, isoform B
- Bub1-related kinase
- Aurora kinase B
- Histone H2A.v
- FACT complex subunit spt16
Sequence:
MPRHSRAKRAPRPSANNSKSPNDDDTAFRSPEPEDGTDYGLEFTTSQLTLQDNNRRSSTLRRDAGRRQPAARDSSTSGEEEDQENRYPTTRSPQTRRMTVQQESKTRAAGPVAAQNQTRRRKAANPMSRAKRMDREIRRLQHHPGTLIPKLPFSRLVREFIVKYSDDEPLRVTEGALLAMQESCEMYLTQRLADSYMLTKHRNRVTLEVRDMALMAYICDRGRQF
Protein: ABI family member 3 binding protein (A0A338P6W9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLSSLGCLLLCGSIALALGNAQKLPKGKKPSLKVHINTTSDSILLKFLRPNANVKLEGFLLGYGSNVSPNQYFPLPTEGKFTEAVVDAEPKYLIVVRPAPPPSQKKSCSGKSRPRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPSDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPNTVYEFGVKDNIEGGIWSKIFNHKTIVGSKNKVNGKIQSTYDQVHSVPVPRKLIPLTIIKQVIQNVTHRASTKSPDKTPFGGTILVHLIIPGLNESTVKLPTSIMLEISDALKAQLAKNETLALPAESKTPEVEKLAGQPVTAPRQTTSMPPKLKTPHSRMPAKEPVPKEPLHTTSKPKMPPSPEVADTTSAPLETRGIPLIPVISPRPSQEELQTAMEETDQSTQELFTTKIPRTTELAKTTQAPHRLHTAPVRPRIPGRPHGRPALNKTTTRPDKTKPRGTSHKNGVGTGTKQAPKPPSPGRNASVDSHATRKPGSVSGTRRPPIPHRHSSTRPVSPERRPLPPNNVTGKPGRAGIVSSSRVTSPPLKATLHPIGTATARPGAEQKEPTAPASEEEFGTTTDFSSSPTKETDPLGKPRFIGPHVRYIPKPENKPCSITDSVRRFPTEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQITNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPISAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLTSEQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW