wanglab/gogpt-training-data huggingface dataset:
Protein: Toll-like receptor 13 (Q6R5N8)
Organism: Mus musculus (Mouse)
Function: Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences.
Subcellular location: Endosome membrane {ECO:0000269|PubMed:22896636}; Single-pass type I membrane protein {ECO:0000269|PubMed:22896636}.
Interaction partners:
- Protein unc-93 homolog B1
- Myeloid differentiation primary response protein MyD88
Sequence:
MSGLYRILVQLEQSPYVKTVPLNMRRDFFFLVVTWMPKTVKMNGSSFVPSLQLLLMLVGFSLPPVAETYGFNKCTQYEFDIHHVLCIRKKITNLTEAISDIPRYTTHLNLTHNEIQVLPPWSFTNLSALVDLRLEWNSIWKIDEGAFRGLENLTLLNLVENKIQSVNNSFEGLSSLKTLLLSHNQITHIHKDAFTPLIKLKYLSLSRNNISDFSGILEAVQHLPCLERLDLTNNSIMYLDHSPRSLVSLTHLSFEGNKLRELNFSALSLPNLTNLSASRNGNKVIQNVYLKTLPQLKSLNLSGTVIKLENLSAKHLQNLRAMDLSNWELRHGHLDMKTVCHLLGNLPKLETLVFQKNVTNAEGIKQLAKCTRLLFLDLGQNSDLIYLNDSEFNALPSLQKLNLNKCQLSFINNRTWSSLQNLTSLDLSHNKFKSFPDFAFSPLKHLEFLSLSRNPITELNNLAFSGLFALKELNLAACWIVTIDRYSFTQFPNLEVLDLGDNNIRTLNHGTFRPLKKLQSLILSHNCLKILEPNSFSGLTNLRSLDLMYNSLSYFHEHLFSGLEKLLILKLGFNKITYETTRTLQYPPFIKLKSLKQLNLEGQRHGIQVVPSNFFQGLGSLQELLLGKNPSVFLDHHQFDPLINLTKLDISGTKDGDRSLYLNASLFQNLKRLKILRLENNNLESLVPDMFSSLQSLQVFSLRFNNLKVINQSHLKNLKSLMFFDVYGNKLQCTCDNLWFKNWSMNTEEVHIPFLRSYPCQQPGSQSLLIDFDDAMCNFDLGKVYFLCSFSMVLSTMVFSWFSTKMIASLWYGLYICRAWYLTKWHKTEKKFLYDAFVSFSATDEAWVYKELVPALEQGSQTTFKLCLHQRDFEPGIDIFENIQNAINTSRKTLCVVSNHYLHSEWCRLEVQLASMKMFYEHKDVIILIFLEEIPNYKLSSYHRLRKLINKQTFITWPDSVHQQPLFWARIRNALGKETVEKENTHLIVVE
Protein: PanD regulatory factor (P37613)
Organism: Escherichia coli (strain K12)
Function: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion. Binding of CoA or a derivative to PanZ leads to interaction with PanD, which promotes the processing and activation of pro-PanD, and subsequent substrate-mediated inhibition of the active form of PanD. Inhibition of PanD activity is probably the primary metabolic role of PanZ, allowing negative feedback regulation of pantothenate biosynthesis by CoA.
Interaction partners:
- Aspartate 1-decarboxylase
- Uncharacterized N-acetyltransferase YjhQ
- Acetyltransferase YpeA
- Uncharacterized protein YjdJ
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- Pantothenate synthetase
- Uncharacterized N-acetyltransferase YedL
Sequence:
MKLTIIRLEKFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARFNERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADAGVEDRGVMTAFMQALGFTAQQGGWEKC
Protein: Adenylyl-sulfate kinase (EC 2.7.1.25) (ATP adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenosine-5'-phosphosulfate kinase) (APS kinase) (Q92203)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Catalyzes the synthesis of activated sulfate.
Interaction partners:
- Sulfate adenylyltransferase
- Phosphoadenosine phosphosulfate reductase
- Sulfite reductase subunit beta
- 3'
- 3'
- Molybdopterin binding domain protein
- FAD synthase
- Elongation factor 1-alpha
- Elongation factor 1 alpha-like protein
- Bis
Sequence:
MATNITHHAGITRNERNQLRKQKGLTIWLTGLSASGKSTIAVELEHQLLQRGLHAYRLDGDNVRFGLNKDLGFSDADRNENIRRIAEVAKLFADSSSIAITSFISPFRADRDTARKLHEVPTPNDSTGLPFVEVFVDVPIEVAEKRDPKGLYKKAREGIIKEFTGISSPYEAPENPEVHVKNVDLPIQEAVKQIIDYLDSKKLLDA
Protein: TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 95 kDa) (TAFI95) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) (Q6PDZ2)
Organism: Mus musculus (Mouse)
Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3 (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q15572}.
Interaction partners:
- TATA box-binding protein-associated factor RNA polymerase I subunit B
- TATA box-binding protein-associated factor RNA polymerase I subunit A
- TATA-box-binding protein
- TATA box-binding protein-associated factor RNA polymerase I subunit D
- RNA polymerase I-specific transcription initiation factor RRN3
- DNA-directed RNA polymerase I subunit RPA49
Sequence:
MDFPGTLRPSLFKAGPLGMTDGPDLSFMCSWRDALTLPGSQPQNCKDPTLSFAKNLLWEPSTPGPLPLLMPPDPDPWDPGVTAQDFLFRGGHCYQYQSQAVLDVTEQLSRFLWDHGDIAFAPLGRLMLENFRLEGNRGYSKKMTIVSAKKLLQDLGGHQPWGCPWASLSRRLRRFSIVGGPVLSRSVSLLMGKLLHEELAMRWEQLLMDEAFTGGALAWLPGRTARAGQLVYPSGGALDKLYFQEVSVTSGGNPRILENPGHVQLRGPVRQVVTSTVQGETLLAVRSDYHCATWKIDKQGPPALLQVMQVEKGATGISLSPHLSGELAICSRSGAVCLWTPQAGLQTIYKDTETLAFRDPSPWRWADFTAHPRVLTVGDRTGVKMVDIQGPPGCGLLLFRAGAEAACQKGERVLLAQYLGQPGQTPPSLHLICTQFSIYLMDERLPLVPMLKWDHGLPSAPLLARLLPPASPGHPRPLLLGGQGGQLQLLHITGEGTSMPQLAGPPQSLPSITESLSAFPLLEPKKQQLLQERLEAPVIGLAAVPLCASAPGLLLFQLSAAGDVFYQHLRLLQASSPRKVPEQATAPSVDQVSTPSWTPQASARCSRWLEDLMELSPTRPLWVAPTFSHRRFLGHMERQKSQETMPQKLRAAMAKGQLLRPGDLSTLPRAEPPPAPQCSQQDELTERLTEAWEGRVTAWWRRHRGETSETQTQSKRPKRRTQLSSTFSSFTSYLDSPDASSAPRSQDLSTSEARLQSPRVPPSQELTQEVWGQGVKRERRQTLRDHTDKLPLKRDTPGPVATPPSQASSLQTMSFRQQTPVHSGSQPPQKKPRMGF
Protein: At3g24730 (mRNA splicing factor, thioredoxin-like U5 snRNP) (Q6NMD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR017199}.
Interaction partners:
- Protein STABILIZED1
- 110 kDa U5 small nuclear ribonucleoprotein component CLO
- 109 kDa U5 small nuclear ribonucleoprotein component GFL
- Small nuclear ribonucleoprotein SmD3b
- Small nuclear ribonucleoprotein Sm D2
- Pre-mRNA-processing-splicing factor 8A
- Small nuclear ribonucleoprotein SmD3a
- Pre-mRNA-processing-splicing factor 8B
- Small nuclear ribonucleoprotein G
- Probable small nuclear ribonucleoprotein G
Sequence:
MSYNSYAEMSYLLKTLTTKEEIDRVIRDTIDEVLVLRFGRSSDAVCLQHDEILAKSVRDVSKFAKVALVDVDSEDVQVYVKYFDITLFPSTIFFFNAHHMKLDSGTADHTKWVGAFHIKQDFIDVVEAIYRGAMKGKMIVQCPIPPERIPKYQLVYKDV
Protein: Biglycan (Bone/cartilage proteoglycan I) (PG-S1) (P47853)
Organism: Rattus norvegicus (Rat)
Function: May be involved in collagen fiber assembly.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Toll-like receptor 2
- Toll-like receptor 4
- Decorin
- Fibromodulin
- CCN family member 4
- Syndecan-1
- Transforming growth factor beta-1 proprotein
- Collagen alpha-1
- Basement membrane-specific heparan sulfate proteoglycan core protein
- Aggrecan core protein
Sequence:
MRPLWLLTLLLALSQALPFEQKGFWDFTLDDGLLMMNDEEASGSDTTSGVPDLDSLTPTFSAMCPFGCHCHLRVVQCSDLGLKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK
Protein: Profilin LP04 (P83647)
Organism: Oryza sativa subsp. indica (Rice)
Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Adenylyl cyclase-associated protein
- Adenylyl cyclase-associated protein
- ADF-H domain-containing protein
- ADF-H domain-containing protein
Sequence:
MSWQAYVDDHLMCEIDGNHLTAAAIVGHDGSVWAQSPNFPQYKPEEITGIMKDFDEPGSLAPTGLFLGGTKYMVIQGEPGVVIRGKKGTGGICVKKTGLSLILGIYDEPMTPGQCNMIVERLGDYLIEQGC
Protein: Uncharacterized protein (Q585F6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAMDEVDFPSGSHDVRNVSKHSRDCRQGVQPTSLHQQYRYLPPNLLPRPPACHSNGIFTDMPASNEFSPDSVTEGVAINMDDSACVSSQFCGSEIRSPNVSGDETSEYSGGRYTVAERGRNENENERGWGEAKAEHDESMAELILTALQRKDDLLREQANTLKQRDLELAHLQGEVAGLREEKRLLLQQLRDCNETDTASKQTASASREQQADITSLNAQNKKLITQLSEARREAEEREEKYTADLQYIHEEMQEFSTLVDEVRSLRAALQQMESNLAGERELRKKCELQYRESTREAEEVLIREREENQKKLKRYKKLYEEAEAAGREATNEAKLLQEELQQLTVNHATLTVTFEVNEQRIADMSEEQAHLRASLQAAREETVILRASLERLRNKEYLEAEDEENCEDETELTFHAHFHTEAERSMYGTRKQLESMVATLERRLSDSEGREQMLSAERERLRTQLQQLSVSARKELLEQQQIADERAAVQRVHIQQLQRELDEKQQQQEEAEERAQAALLRAQEQFREACSELQQVKEERATAAGEESRRHVLFEKQIAKVLQALQNKLSRRNVECRMLKQQIKLNEEQNRKRLETNVSEPVRQDRRPPVQNMKDGSRVTRPARLPLHNTVVKQEVLLAAAQPTALQEQRADAHTARFTAPQSPACEYNCIEARLNEALARTTELEEQLQAKRRKYCAMVKDRKMLMERVEKQQQKQQRQIATLEDMQRETLRKLESTHRRRMSSAFAAAAEGNKRQQWVIQRGVARVVAELVEFIHELESYATVVGDRYVTRAASQNTKEKNHRVRLTYDSPPQDALSERENILRAACDDITRNFLGVNGGWEALCQSNSFTCSDISASFSFGKAIPQAMRQRVRCRIADYLKSQLLGTNSSRTGTGVTTTPGEMHKRSVGGGGNNKRTMNLSFGLHGEVEEERWLHGEPYAGAHGRSNRNLGTVPGSSSGESLIDVLMECVRYIFQA
Protein: G-protein coupled receptor 157 (Q8C206)
Organism: Mus musculus (Mouse)
Function: Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.
Subcellular location: Cell projection, cilium membrane {ECO:0000269|PubMed:27142930}; Multi-pass membrane protein {ECO:0000255}. Note=Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid. {ECO:0000269|PubMed:27142930}.
Interaction partners:
- Protein LZIC
Sequence:
MPSPAPPTELLPWERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQDFAGTSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVRTTRGPSTDHLIWAFHLISWGVPLAITVAAVSLKKIGYDASDVSVGWCWINLEAEDRVLWMLLTGKLWEMLAYILLPLLYLLVRKHINRAHQALSEYRPICEGRQLQRGSSTSTADKKLVLIPLIFICLRVWSTVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCPRPSTQSPPGAPTPPKIGESQESRRTPEVPST
Protein: TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit) (O43133)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Subcellular location: Nucleus.
Interaction partners:
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 9
- Taf145p
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 13
- TAFII55 protein conserved region domain-containing protein
- TAFII28-like protein domain-containing protein
- Transcription initiation factor TFIID subunit 4
Sequence:
MDLKLPPTNPTNPQQAKTFMKSIEEDEKNKAEDLDIIKKEDIDEPKQEDTTDGNGGGGIGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIRDPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKLGFNAKFCDFKIQNIVGSTDVKFAIRLEGLAFAHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKKREEIYDAFESIYPVLNEFRKN
Protein: Probable mitochondrial import inner membrane translocase subunit TIM21 (Protein SEGREGATION DISTORTION 3) (Q1G3L1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May participate in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit TIM23-2
- Mitochondrial import inner membrane translocase subunit TIM23-3
- Mitochondrial import inner membrane translocase subunit TIM17-2
- Mitochondrial import inner membrane translocase subunit TIM23-1
- Mitochondrial import inner membrane translocase subunit TIM44-2
- GrpE protein homolog 1
- Mitochondrial import inner membrane translocase subunit TIM17-1
- Mitochondrial import inner membrane translocase subunit PAM16 like 2
- Mitochondrial import inner membrane translocase subunit TIM17-3
Sequence:
MMMMNLLRRSAIAIGRQSKSKLASFSSATQPCSGIPKSSKRVFSNSFLSKDSTGANGLLFRFRNPQASICTEARPKNINSSYFTRSFASRTSKEPGNQQNKAKKEVTTVEDPFDSPTYHIPEKPVTFTEGASYSLVILAGLGVAGAAGYGVFKELIFQPKEYKVFDKALKRIQDDGQVRVRIGSPIKGYGQETRNRAARQRIPNRVFTDEDGVEHVEVNFYIRGPQGAGKVYTEMFKDKAEKEWKYTYLIVEILTPSPAKLMLESYLPA
Protein: N-(5'-phosphoribosyl)anthranilate isomerase 1, chloroplastic (EC 5.3.1.24) (Q42440)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the conversion of 5-phosphoribosylanthranilate to l-(O-carboxyphenylamino)-l-deoxyribulose-5-phosphate, which is the third step of the tryptophan biosynthetic pathway.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Indole-3-glycerol phosphate synthase, chloroplastic
- Anthranilate phosphoribosyltransferase, chloroplastic
- indole-3-glycerol-phosphate synthase
- Tryptophan synthase
- Anthranilate phosphoribosyltransferase
- Tryptophan synthase alpha chain
- Tryptophan synthase beta chain 1, chloroplastic
- Tryptophan synthase alpha chain, chloroplastic
- anthranilate synthase
- Tryptophan synthase beta chain 2, chloroplastic
Sequence:
MSTGISTDLHVHFGALNFSKTYKSGLSNRTVSFSRVGYAQNRKLSCSVSNTENVAPKDDERGKDRPLVKMCGITSARDAAMAVEAGADFIGMIIWPHSKRSISLSVAKDISKVAREGGAKPVGVFVEDDENTILRAADSSDLELVQLHGNGSRAAFSRLVRKRRVIYVLNANQDGKLLNEVPEEDCHLADWILVDSATGGSGHGFNWAQFKLPSVRSRNGWLLAGGINPTNVSEALSILQPDGIDVSSGICGTDGIQKDKSKISSFITAVRSVHY
Protein: Mesothelin (Pre-pro-megakaryocyte-potentiating factor) (Protein expressed in renal carcinoma) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form] (Q9ERA7)
Organism: Rattus norvegicus (Rat)
Function: Membrane-anchored forms may play a role in cellular adhesion.
Subcellular location: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Golgi apparatus {ECO:0000250}.; SUBCELLULAR LOCATION: [Megakaryocyte-potentiating factor]: Secreted {ECO:0000250}.
Interaction partners:
- Mucin-1
- Uroplakin 3B
- Receptor protein-tyrosine kinase
Sequence:
MALPTAQPLLGSCGSPICSRSFLLLLLSLGWLPLLQTQTTRTSQEAALLHAVTGTVDFASLPTGLFLGLMCDEVSGLSMGHAKELAMAVRQKNIVLQVHQLRCLARRLPKHLTNEELDALPLDLLLFLNPAMFPGQQACAHFFSLISKANVNVLPRRSLERQRLLTGALKCQGVYGFQVSETDARALGGLACDLPGEFVAKSSEVLLPWLARCGGPLDQGQAKAVREVLRSGRAPYGPPSTWSVSTLDALQGLLVVLDESIVHSIPKDVITEWLQGISREPSRLGSKWTVTHPRFRRDTEQKACPPGKEPNVVDENLIFYQNWELEACVDGTLLAGQMDLVNEIPFTYEQLSIFKHKLDKTYPQGYPESLIKQLGHFFRYVSPEDIRQWNVTSPDTVNTLLKVSKGQKMDAQVIALVACYLRGGGKLDEDIVKALDNIPLSYLCDFSPQDLHAIPSSVMWLVGLHDLDKCSQRHLGILYQKACSAFQNVSGLEYFEKIRTFLGGASREDLRALSQHNVSMDIATFKKLQVDALVGLSVAEVQKLLGPHIGDLKTEEDKSPVRDWLFRQQQKDLDSLGLGLQGGIPNGYLILDFNVREAFSSGAPLLGPGFVFAWIPALLSALRLS
Protein: SET domain-containing protein 3 (P36124)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Required for both gene activation and repression. Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis. Required for the transcriptional activation of genes with high activity.
Interaction partners:
- Probable DNA-binding protein SNT1
- Protein HOS4
- SIR4-interacting protein SIF2
- Probable histone deacetylase HOS2
- Peptidyl-prolyl cis-trans isomerase
- NAD-dependent protein deacetylase HST1
- Transcriptional regulatory protein PHO23
- Transcriptional regulatory protein RXT2
- Histone deacetylase complex subunit CTI6
- Helicase SWR1
Sequence:
MSVPNSKEQSLLDDASTLLLFSKGKKRAEEASKIGSKTDTIEHDESHEREKKGAIEMAAAALATASTVSLPLKKATEQSAAEAATSTAAKEETENQPQKQPQWPVPDSYIVDPDAGIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERINVKTVEPSSSNNSASNKNNGRDRASSTTISDVGDSFSTDQDNTNHRDKRRKRNPSNNSIDSKNESASVNSSDGLTSMPKKKEHFLSAKDAYGAIYLPLKDNVFKSDLIEPFLNKHMDDNWVIQYPHKTFKSVSIEVKPYADIAYSRTYPGFTKLGVYLKKDCIKGDFIQEILGELDFYKNYLTDPRNHYRIWGTAKRRVIFHSHWPIYIDARLSGNSTRYLRRSCQPNVELVTIKLQDTDNRNDKSSGRKSSRIKFVLRALRDISEDEELYIKWQWDSKHPILKLIKGMTIDSLDDLERYGLINSVETILSNGECGCGNNSKDCYLLKVKRYAQSLYKSVKSRGKMNNRYKLNEILNQYNCKKRREPPILHRLEEKAQNTIERAPILLNNFYRQKFLNRNNGPKIPQKNTIDSTNNPDDIAKPFKFALFAQHSSNISVPKKNETSEKPLIITKSTDYDESHITNIEELPIPVLLPINKTSRQTANDVEESQSKNEHKLSRTPSLSNFNKELSKEAQHSQAKTKEIMTEASVNSRRESTPESIMHLSDFSSSQLHSKKKLSFADYRKKLLK
Protein: Uncharacterized protein, isoform A (Uncharacterized protein, isoform B) (Q9VBS6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSEATTNGHNEVPANNLPSWLSKISLEKAVQAQIGDFEKIISVIPQKGSSDGDNYSTQFLRLLVEVELIDHSTKDLSFVLKAQHSNEMMAAILAKLKLFQKEEQMYHSILPKFEKLYADAGKPIQFAPKAFKFDRDLGVDYILLEDLHRKNFKNANRLAGLDLDHMHKVLEKLAAFHAASACYVEHHGLFGEEFTVGVFSESNRQLLQEFNASGAFLAQLKKWKNAQKIYEKLADSDDYLVDRLLQDQQYNTREFNVLNHGDCWANNVMYQHDAFGTIKETLFVDFQVGKYGSPANDLYYLILSSAAPELKTAKFDYLVRYYFDNLIENLKLLQYHRPLPKLKNLHASLFRNGLAAYMVVSKVLPVVMLDKTADANLESYISDESKMKNAMFTNPKYVQVMTEVLPWLDNRGLLDLK
Protein: Chloride channel protein (G5EC75)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
Interaction partners:
- Coelomocyte uptake defective protein 15
- Clc-like protein 2
- Boca/MESD chaperone for YWTD beta-propeller-EGF
- Battenin
- Battenin
- Battenin
Sequence:
MTSRNRVRTSSNSLDPNEDPVSGLERVMSNSNLEHVARQRRRLEEELLFSRQLDDVGRTDSHEALSARYESLNYEISENRLYRDAEKKPSHQLTLWRISRNRWFVCFLIGVFTGLVAAFIDIMVHYSKDIKFNWILKYLLSKCGEEQRGTTAGCMWTVMIAWIGYNCVLVTIAAILVIYVAPIAGGSGIPQIKCYLNGIAIPEVVRLKTLVSKAVGVACSVGGGLCAGKEGPMIHSGAAVGAGISQGKSYSLGIDFGLFREFRNDREKRDFVSAGAAAGVAAAFGAPIGGVLFSLEEGASFWNQALTWRMFFSAMISSFTVNWILSWFNGRSGWLSWTGLANFGVFENKDYNIWEIPLFLLIGIIGGCLGALFNYLNTKLTEFRKKYVSSKLGRLFECLLVAAVSGFLAFLTIFAIDDCQPIGANPTATSTQINQMWCKKGEYSAVASLFFQNPEESVKSMFHSPINSFGVTTLVIFGIEYFLLTLWTFGISVPSGVFIPAILTGAAWGRLFGIFVERLFPSVTGIDPGKYALAGAAAQLGGVVRMTISLTAIIMEATKDITFGLPIMLVLMVTKWVGDMFNEGLYDAHIDLAEVPILGWNPPKMSRNILADRVMRKDVVALERRERVSRIVEILRSTLHHGFPVVDRIEESPYESLPDYGRLKGYILRSQLFKLLENRIFEEEGASNSALPNDFYECQDDDDQMKSVAELGLTNFDESCFLDIEPYMHPHPHRVPLNTSLPFIFRLFRGLGLRYLFVVNDDNHLRGVITRKDVARFRERRRNREYHVDELYISES
Protein: Phosphate transport (Pho88) (Q386K5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNIILIGLVMVTGWSIDKTDPEVQSVVQYMFYSVHAVLAAVMIYMFSRIWDTKDTRILQVKDTYTGEWERMTVSDYDFGKWREMFFLKMMLPVCIGLFVALRWEMPLVLLVQCVTNPIVAWNAPVTQLYLRGFKEEGPLVRPWKDEVATVEWMREMFGLAREEQDKFLSGQNGTKGRKGQ
Protein: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (NAD-dependent glyceraldehyde-3-phosphate dehydrogenase) (P46795)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Phosphoglycerate kinase
- Triosephosphate isomerase
- Fructose-bisphosphate aldolase
- Enolase
- Glucose-6-phosphate isomerase
- L-lactate dehydrogenase
- Uridine kinase
- Pyruvate kinase
- Thioredoxin
- Glucose-6-phosphate 1-dehydrogenase
Sequence:
MKLAINGFGRIGRNVFKIAFERGIDIVAINDLTDPKTLAHLLKYDSTFGVYNKKVESRDGAIVVDGREIKIIAERDPKNLPWAKLGIDVVIESTGVFSSATSDKGGYLDHVNHAGAKKVILTVPAKDEIKTIVLGVNDHDINSDLKAVSNASCTTNCLAPLAKVLHESFGIEQGLMTTVHAYTNDQRILDLPHSDLRRARAAALSIIPTSTGAAKAVGLVLPELKGKLNGTSMRVPVPTGSIVDLTVQLKKKDVTKEEINSVLRKASETPELKGILGYTEDPIVSSDIKGNSHSSIVDGLETMVLENGFAKILSWYDNEFGYSTRVVDLAQKLVK
Protein: Lectin-related NK cell receptor LY49L2 (Natural killer cell receptor Ly-49L2) (Q9JIQ1)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MSEQEVTFSAVRFHKSSGLQNRVRLEETGKPQKAGLRVCSVPWQLIVIALGILISLRLVIVSVLVTNIFQNSQQNHELQETLNCHDKCSTTTQSDINLKDELLSSTSIECRPGNDLLESLHKEQNRWYSETKTFSDSSQHTGRGFEKYWFCYGIKCYYFVMDRKTWSGCKQTCQISSLSLLKIDNEDELKFLKLLVPSDSCWIGLSYDNKKKDWAWINNGPSKLALNTMKYNIRDGGCMLLSKTRLDNDNCDKSFICICGKRLDKFPH
Protein: Cadherin-15 (Cadherin-14) (Muscle cadherin) (M-cadherin) (P55291)
Organism: Homo sapiens (Human)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Catenin beta-1
- Catenin delta-1
- Catenin alpha-1
- Cadherin-6
- Cadherin-20
- Cadherin-19
- Cadherin-7
- Cadherin-10
- Cadherin-2
- Myogenic factor 5
Sequence:
MDAAFLLVLGLLAQSLCLSLGVPGWRRPTTLYPWRRAPALSRVRRAWVIPPISVSENHKRLPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPELFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIITLDDINDNAPEFTRDEFFMEAIEAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESCEHYELKVSVQNEAPLQAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATDEDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQVPEGLHRLSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGALVIVLASALLLLVLVLLVALRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPLGPPPLRRDAPQGRLHPQPPRVLPTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYEGDGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYGHPCGLEYGARWDHQAREGLSPGALLPRHRGRTA
Protein: Ankyrin repeat domain 27 (K7ELM1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MALYDEDLLKNPFYLALQKCRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIPVEEHFQTLNGKDVFIQGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEKRESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSANALYTKCLQQLLRDSHLKMLAKQEAQMNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIEYIRQGSLSAKPPVRSHPCPGLPLWASWFP
Protein: Protein tesmin/TSO1-like CXC 6 (AtTCX6) (Q9SL70)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in development of both male and female reproductive tissues.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Retinoblastoma-related protein 1
- Transcription factor-like protein DPB
- WD-40 repeat-containing protein MSI5
- Proline-rich spliceosome-associated
- Protein ALWAYS EARLY 3
- THO complex subunit 4B
- WD-40 repeat-containing protein MSI4
- Protein ALWAYS EARLY 1
- Transcription factor E2FC
- Protein ALWAYS EARLY 2
Sequence:
MGEGEEGDKFPPKTDEVTQESMKSARQLDFTGGSSDVEHSHSNQASSMAAASIPSPIVTVTRPIITSQAPPTVATPIPPPPQSQGIILHVPIRHPRPESPNSMPRPAGETRDGTPQKKKQCNCKHSRCLKLYCECFASGTYCDGCNCVNCFNNVENEPARRQAVESTLERNPNAFRPKIAASPHGGRDNREEVGDVVMLARHNKGCHCKKSGCLKKYCECFQANILCSENCKCLDCKNFEGSEVRQSLFHGEHSHNLAYLQHANAAITGAIGSSGFASAPPPKRRKGQEIFFNQGTKDSSTHRLGQANNGRTTSSQTGSRAGGNASLGPSKVVYKSLLANIIKPMDVKALCSVLVAVAGEAAKTLTEKRLANQKETSVASSVQDQGHVNNKAEKSGLEDSNADGSKGRSLSPETLALMCDERDTMLMVAASPNCSVEPTSQLPNGQDQVYAEQEKVVLTKFRDCLNRIISCGEVKESNCSMSRMDLDTPVQTTVRIDPVVQQAPVANGVSQTAKQPSQLNTTTPNTSSQTANGVSQTAKQPSQLTTTTTTPNTSSQTHLHKTPALSEKKDL