wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger transcription factor ref-2 (Regulator of fusion 2) (Zic transcription factor ref-2) (Q7JNM3)
Organism: Caenorhabditis elegans
Function: Transcription factor. Modulates expression of target genes by binding to regulatory elements. Required for normal cell division timing and cell positioning in anterior lineages, acting in a cell-autonomous manner. Required for development, fusion and fate of cells of the ventral epidermis, the Pn.p cells, during larval development; acts in concert with homeobox genes lin-39 and mab-5. Required for the specification of the AIY interneuron. In complex with TCF transcription factor pop-1, positively modulates expression of LIM/homeobox protein ttx-3 in anterior daughter cells of the SMDD/AIY neuron lineage.
Subcellular location: Nucleus {ECO:0000269|PubMed:12091304, ECO:0000269|PubMed:19386265, ECO:0000269|PubMed:35660370}. Cytoplasm {ECO:0000269|PubMed:19386265}. Note=Localized to nucleus during interphase in cells giving rise to SMDD/AIY neurons, then in cytoplasm just before cell cleavage. {ECO:0000269|PubMed:19386265}.
Interaction partners:
- Protein pop-1
Sequence:
MSIPANTIQKDKMMHSDYYTQSQGPTVEQQPEWQASVQPYSDPHAYSPSFYMNMSQVPHFLPAQVDPFIYPNTLGSYGGDKQVQCLWETNGQVCMHVCQNSGELSTHISSNHITHDSKFVCLWKGCDREFKMFKAKYKLVNHMRVHTGERPFLCDVCNKVFARSENLKIHKRIHSGEKPFQCTHNGCTKLFANSSDRKKHMHVHSSHKPYSCMYPDCGKTYTHPSSLRKHTKVHENEKKSQLSPEHDESSDSGNASIGTPTTDESLTFSPENIKRDQHLHTMHTFMDRPNPFMQMYQNQFSNPTYHMFMAKPDSY
Protein: Organic hydroperoxide resistance transcriptional regulator (O34777)
Organism: Bacillus subtilis (strain 168)
Function: Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements.
Subcellular location: Cytoplasm.
Interaction partners:
- Organic hydroperoxide resistance protein OhrA
- Organic hydroperoxide resistance protein OhrB
- Peroxide operon regulator
- Bacilliredoxin BrxA
- Bacilliredoxin BrxB
- HTH-type transcriptional regulator YodB
- Thioredoxin reductase
- N-acetyl-alpha-D-glucosaminyl L-malate synthase
- Bacilliredoxin reductase Bdr
- Putative cysteine ligase BshC
Sequence:
MENKFDHMKLENQLCFLLYASSREMTKQYKPLLDKLNITYPQYLALLLLWEHETLTVKKMGEQLYLDSGTLTPMLKRMEQQGLITRKRSEEDERSVLISLTEDGALLKEKAVDIPGTILGLSKQSGEDLKQLKSALYTLLETLHQKN
Protein: Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like) (Q9HAJ7)
Organism: Homo sapiens (Human)
Function: Functions as transcription repressor, probably via its interaction with histone deacetylase complexes. Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus. Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA. Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import.
Subcellular location: [Isoform 1]: Nucleus, nucleolus {ECO:0000269|PubMed:14680513, ECO:0000269|PubMed:16820529, ECO:0000269|PubMed:18070604, ECO:0000269|PubMed:19015240}.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus, nucleolus {ECO:0000269|PubMed:18070604}.; SUBCELLULAR LOCATION: [Isoform 3]: Nucleus, nucleolus {ECO:0000269|PubMed:18070604}.
Interaction partners:
- Paired amphipathic helix protein Sin3a
- Histone deacetylase 1
- Histone deacetylase complex subunit SAP30
- Inhibitor of growth protein 2
- SIN3-HDAC complex-associated factor
- Histone-binding protein RBBP7
- Histone deacetylase 2
- Sin3 histone deacetylase corepressor complex component SDS3
- Histone deacetylase complex subunit SAP18
- Breast cancer metastasis-suppressor 1
Sequence:
MNGFSTEEDSREGPPAAPAAAAPGYGQSCCLIEDGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDTDIPEVDLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNKSRLDQKSEGGKQLE
Protein: Microsomal glutathione S-transferase 2 (Microsomal GST-2) (Microsomal GST-II) (EC 1.11.1.-) (EC 2.5.1.18) (EC 4.4.1.20) (Glutathione peroxidase MGST2) (Leukotriene C4 synthase MGST2) (Microsomal glutathione S-transferase II) (A0A8I5ZSH5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU369123}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU369123}. Microsome membrane {ECO:0000256|RuleBase:RU369123}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU369123}.
Interaction partners:
Sequence:
MAGDSSLLAAVSLLSACQQSYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFYSVFIISLWMAGWYFNQGSLVSG
Protein: ADP-ribosylation factor-like protein 8B (Novel small G protein indispensable for equal chromosome segregation) (G5EDC6)
Organism: Caenorhabditis elegans
Subcellular location: Lysosome membrane {ECO:0000256|ARBA:ARBA00004656}.
Interaction partners:
- Kinesin-like protein unc-104
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- KxDL domain-containing protein
- Vacuolar protein sorting-associated protein 39 homolog
- Kinesin light chain
- BLOC-1-related complex subunit 5
- Kinesin light chain
- Vacuolar fusion protein CCZ1 homolog
- Vacuolar protein sorting-associated protein 18 homolog
- Liprin-alpha
Sequence:
MLAMVNKVLDWIRSLFWKEEMELTLVGLQNSGKTTFVNVIASGQFTEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVNAIVFMVDAADEEKLEASRNELMQLLDKPQLDAIPVLVLGNKKDLPGALDERQLIERMNLSSIQNREICCYSISCKEKENIDITLQWLIDHSKAQR
Protein: Arylsulfatase L (F5H324)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSGSRERDNMLHLHHSWTPNIDRLAEDGVKLTQHISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATGLIGKWHLGLNCESASDHCHHPLHHGFDHFYGMPFSLMGDCARWELSEKRVNLEQKLNFLFQVLALVALTLVAGKLTHLIPVSWMPVIWSALSAVLLLASSYFVGALIVHADCFLMRNHTITEQPMCFQRTTPLILQEVASFLKRNKHGPFLLFVSFLHVHIPLITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQDRVIDGQDLLPLLLGTAQHSDHEFLMHYCERFLHAARWHQRDRGTMWKVHFVTPVFQPEGAGACYGRKVCPCFGEKVVHHDPPLLFDLSRDPSETHILTPASEPVFYQVMERVQQAVWEHQRTLSPVPLQLDRLGNIWRPWLQPCCGPFPLCWCLREDDPQ
Protein: Acetoacetate decarboxylase (O53564)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Steroid C26-monooxygenase-3-oxocholest-4-en-26-oate forming])
Sequence:
MPVSQHTIAGTVLTMPVRIRTANLHSAMFSVPADPAQRLIDYSGLRVCEYLPGKAIVMQMLVRYVDGDLGRYHEYGTAIMVNPPGTQRRGPRALTRAAAFIHHLPVDQVFTLEAGRTIWGFPKIMADFNVTDGRRFGFDVSADGRLIAGIEFSTGLPVPTLGWQMLKTYSHHDGVTREIPWEMKVSGLRARLGGARLRLGDHPYAKELASLGLPKRALLSQSAANVEMTFGDGHPI
Protein: Vacuolar protein sorting-associated protein 41 homolog (A0A8I5ZWM9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endosome membrane {ECO:0000256|PIRNR:PIRNR028921}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR028921}. Late endosome membrane {ECO:0000256|PIRNR:PIRNR028921}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR028921}. Early endosome membrane {ECO:0000256|PIRNR:PIRNR028921}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR028921}. Lysosome membrane {ECO:0000256|PIRNR:PIRNR028921}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR028921}. Golgi apparatus, trans-Golgi network {ECO:0000256|ARBA:ARBA00004601, ECO:0000256|PIRNR:PIRNR028921}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000256|PIRNR:PIRNR028921}. Late endosome {ECO:0000256|ARBA:ARBA00004603}.
Interaction partners:
Sequence:
MGYSDFPTTKCVFFSNLLSLPCLQETESLEESTDESEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKLQVFGLYSGEEFHETFDCPIKIVAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDITSKQRITNVPRDDISLRPDMYPCSLCWKDAVTLIIGWGTSIKICSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISHRNIKRHKILEIGLAYVNHLVERGEYDMAARKCQKILGKNASLWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSLNAPAQYCNICSAKNRGPGSAILEMKK
Protein: Mitogen-activated protein kinase 4 (EC 2.7.11.24) (LmxMPK4) (Q9GRU1)
Organism: Leishmania mexicana
Function: Essential for the two main proliferating life stages, the promastigotes and amastigotes, of the parasite.
Interaction partners:
Sequence:
MTQLVPLAELPSGKKIYSVRGQRFEVDRQYDLVKVVGFGACGTVCSAVVNGSGERVAIKRLSRVFGDLREGKRILREMEIMTSLKHNNLIRLHHFMRPQSKETFEDIYLVMDLYDTDLNRIIRSRQKLTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARDDQVMSSSDLTQYVVTRWYRPPEVLGMGSNQYTSAVDVWSLGLIFAELMVGRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSEAKAFILSQPHRPALSFRDLFPMATEEATDLLSKLLVFHPARRLTAKQVMEHPYFSKYRDAAEEADAPDPFVWNHSHIETKEQLREDLWRVVEAHSQLNE
Protein: Fgr2p (A0A1D8PQL0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- RING-type E3 ubiquitin transferase
Sequence:
MSDIEKKQTKISPASSVAHDEDTLANDELFQLTDSVLNKKLKLINDAIDEIGFTPYHLKLFFLNGMGYWTDTQLTYLESSVRTFVNYQFGYKYPVSNEMLAAGLLVGALFWGFSADLIGRRLAFNLTLLLSALFTILTGVMNNMASYCIFVFLSCFAAGGNLVLDTCIFLEFLPHKDQWLLTFFAFFWGIGQTIAVALAYAFLPNNSCESADNCPSHINRGWRYVYYTNGSIVLAMAILRLTLIRLQETPKFLVSNNRDQEAVEILQRIAQKHNRTCSLTIEDLESLGKVEINDDYRKHIDIKGTFRLVTHHVQILFSNRTMARSSVLVFVSWLLLGISYPLYSSFLPVYLATRGANISAPDVHGVYRDNLISNCVSMGGPLIAGALLFCFPWLGRRGVLFIGGVASMAFLFGYTQIKTRAQNVALSSISFASMYIYYSALYAYTPEVFPSVARATGNAIAIACTRVMTCIVPVIAYYSNTSSSVPIWVCGAFVGVIGFLALLFPYEPSKQRVV
Protein: Uncharacterized protein C119.18 (Q96VG1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Protein ups1 homolog
- UPS-like protein C36.10
- Vacuolar amino acid transporter 5
- Mitochondrial inner membrane protease atp23
- Mitochondrial distribution and morphology protein 10
- Autophagy-related protein 2
- Mitochondrial distribution and morphology protein 12
Sequence:
MSSSVSEECTPAKKKYDACFNDWYANKFLKGDLHNRDCDELFAEYKSCLLKALKTKKIDPLLEAARKED
Protein: Endonuclease G, mitochondrial (Endo G) (EC 3.1.30.-) (Ced-3 protease suppressor 6) (Q95NM6)
Organism: Caenorhabditis elegans
Function: Endonuclease important for programmed cell death; it mediates apoptotic DNA fragmentation.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11452313}.
Interaction partners:
- Pyr_redox_2 domain-containing protein
- Flap endonuclease 1
- Zinc phosphodiesterase ELAC protein 2 homolog
- 3'-5' exonuclease crn-4
- Exosome complex component RRP46 homolog
- Cell death-related nuclease 6
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Apoptosis regulator ced-9
- Exosome complex component 10 homolog
- Deoxyribonuclease TATDN1
Sequence:
MIGKVAGTAAIAGISFLAGKYSNDDLPIFRNVQSATNVPMNQIQVSEPMTVKPASLNADAMGPSRSAEIMKHGYPGFTNVRTYEDFVLSYDYKTRTAHWVCEHLTPERLKHAEGVDRKLCEFKPDITFPQKFLSQNTDYKCSGFDRGHLAAAGNHRKSQLAVDQTFYLSNMSPQVGRGFNRDKWNDLEMHCRRVAKKMINSYIITGPLYLPKLEGDGKKYIKYQVIGDNNVAVPTHFFKVALFEVTPGKFELESYILPNAVIEDTVEISKFHVPLDAVERSAGLEIFARLDPKSIVKENGAKKGGLLW
Protein: SANT and BTB domain regulator of class switch recombination (SANT and BTB domain regulator of CSR) (Q68FF0)
Organism: Mus musculus (Mouse)
Function: Negatively regulates class switch recombination or isotype switching in splenic B-cells.
Interaction partners:
Sequence:
MSRGYPENNNFLNNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECVKRFDELKSCGSSPVDNQYNPLMATGEGPVETLATYIKSSLLDTQGDFQETPVDQDTVSKAGRHSIATTRNCSSESENCTARNAGEETGESEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKESKDCEIPALEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINANLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDPEYSNPDSRNNAATLYRCCLCKKLLTRETERRIPCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTVNWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSTVNSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVVLHDQGENDDSPSCPPAKILDDLHKHKDVIAVPFLKDAVSDPGVGSCDEKGLEYEILLEPNTPWGSKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEIAKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDASRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQVRASVPVTARQNSSDKNQRSKSRFGQGRPA
Protein: DNA-directed DNA polymerase (EC 2.7.7.7) (Q57UM9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA polymerase
Sequence:
MRRTFSRYARFAVCQQSTGAGTIEGPLRLRSADQTVVWCCAAAGRRSWFCLLPNSVRAGLHEPRRFASTRATNSRKPARVARSGASSRAPRKGPRHSQGLKSSQESEGEFMATTSDDDFGPMAEGAAEEESAGDCDAGVGSSLTGGRETTESSNVAAAPEEEGEGVGTTEGVETEGGKPGRSEEDPLNLRVATLMQQPGKAFRVIAVSYSAKRELNFPITFEDIASGTTLNCRLEDVHTTYMNWVRQFCASWVMLFVPTLSAASAVLLENAVVYSRVERTVSNSHRGSPAPKQWEEPDHVLVSYSKMREVLCKVKRDEQVDKELVSNTVLSAFAEDWKSFIHSTASCSPASIVTASFDFRPNGGHLQLNKKFLHAQLTTAAMTLLRHVARKGSSASGTPCSSSTKEVTSGANNSVADDIRRKESWLLIFVSAPAGSATSFLGPRAVNLGVPPMQDLLTGEFVDPLLLGGRNVIYIIGSGTAAEAFSKIPSVRKGKRQISILLKDIENQLGPFRASRPTLTTTLIQALDTFSRHTWIGLMKEEDGTVRVPRAPQSFVHLHRRSVTREVLPKFLESTLGHISHHNSAYGVAEVGMGGAAGAAGANALLQLGKLNRKVDEHIKAIFNNAERLEKEKALRESLRRSNCFFVDVKSANISAARRADNPFSTRNGILEFHGQLWATLGMGETARAGKTTGCPPVKTLTAQLAPNGDVQAFVRPEECIPMELPTGSSDTSTIRHKGISLAASASSASSGIIIAWDVKRALLFLRGSNRLREFLLNGGRIWCAQYAQYLLKGFNNHNLTTMERTLLQYHTVQTKLHPLEKLKIIFEKQLDIAVNTRQLISIVHRMDGLLACTEMELRGLQIAPQEDITAFARNLKRTREELEKAVNDKIMVFTEGMDNEVRRKINVRSTQDISTIIYGGALCRHLGTRYVSPHIPRIPVTAIFPHAVCRLTTTPVPELYTNAENLLGVKGTGNSGNNNNANKIAEAATITANAVNTTLKIIDKYLKDNTLDNLLNNTAIVVVTCKVRTSSFLEVITIHCPSSDPNDELRHTVAIDDVLPVMSSPELVTITQLKEKIAAYRPLRALQPLKKYGRRSYDLRNLVILTHCSFDKTAVLVDTGIIQTIAETVLGKENEERSLLERVCFCDINRAFPPPPEGGDSFENDFLGLVNGAEQAGVSSRSNWEAFTRNFAAVGGFEDTRRALVLHCASLVGTARDPFRTAHPLPFALVGFNGQQALGLHGQERASTRGMLWMVTPERLHPLLHRSLRGRSASSGADAIERINVLLSNEKQVDLSFFKALQQLRFMEKQMQLFEEGALFRAVLPECKNRVHGEFCHVVTATGRLSSQSPNLQNIPKEDLRCLIVSRFGRRAGRMIEADYSQLEVVVLAALSRDARMLQELNDNVDFHCLRVSLMTKEPYEDVIHKVKQVKDPHYIQLRQQAKTFSFQRQYGAGTSTIATTTGLSETEVVRLIAAEEQHYKDLGRYYRLVTDCVEAGADRLLQLRTLDATSWPPTMRRMVLLTEPMHYFVVPTGSKFDFTKDKKAVPRLKNYPVQGLAGEIVQIMCGKIIRRFYAKRNYNDKAFLVNTVHDCVWIDAHESVADEVMDDVSAIMSSTSEVISSLWPGVKLDVPFKAEIHIGPSLGELSR
Protein: Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA] (Q00731)
Organism: Mus musculus (Mouse)
Function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.
Subcellular location: [N-VEGF]: Cytoplasm {ECO:0000250|UniProtKB:P15692}. Nucleus {ECO:0000250|UniProtKB:P15692}. Note=Cytoplasmic in normoxic conditions and localizes to the nucleus under hypoxic conditions. {ECO:0000250|UniProtKB:P15692}.; SUBCELLULAR LOCATION: [VEGFA]: Secreted {ECO:0000250|UniProtKB:P15692}.; SUBCELLULAR LOCATION: [Isoform L-VEGF-2]: Endoplasmic reticulum {ECO:0000250|UniProtKB:P15692}. Golgi apparatus {ECO:0000250|UniProtKB:P15692}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P15692}.; SUBCELLULAR LOCATION: [Isoform VEGF-1]: Secreted.; SUBCELLULAR LOCATION: [Isoform VEGF-2]: Secreted.; SUBCELLULAR LOCATION: [Isoform VEGF-3]: Cell membrane; Peripheral membrane protein. Note=Remains cell-surface associated unless released by heparin.
Interaction partners:
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- Neuropilin-1
- Fibronectin
- Basement membrane-specific heparan sulfate proteoglycan core protein
- Matrix metalloproteinase-9
- CCN family member 2
- Epidermal growth factor receptor
- Fibroblast growth factor 2
Sequence:
MTDRQTDTAPSPSAHLLAGGLPTVDAAASREEPKPAPGGGVEGVGARGIARKLFVQLLGSSRSVVAVVCAAGDKPIGAGRSASSGLEKPGPEKRGEEEKEEERGPQWALGSQEPSSWTGEAAVCADSAPAARAPQAPARASVPEGRGARQGAQESGLPRSPSRRGSASRAGPGRASETMNFLLSWVHWTLALLLYLHHAKWSQAAPTTEGEQKSHEVIKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNITMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKKSVRGKGKGQKRKRKKSRFKSWSVHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
Protein: Spore photoproduct lyase (EC 4.1.99.14) (Q97L63)
Organism: Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)
Function: Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5,6-dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines.
Interaction partners:
- AP superfamily
- Anaerobic ribonucleotide reductase
- Endonuclease V
- GTP 3',8-cyclase
Sequence:
MENMFRRVIFEKKALDYPMGRDILRQFENTDIEIRYSETGRITGIPGKDEAQSFFEGKNTLVVGVRRELDFQTCKPSANYQLPIVSGCAAMCEYCYLNTHGGKKPYVKINVNLDDILSKAGEYIEKRKPDITVFEGAAISDPVPVERYSGALKKAIEYFGKNEYSRFRFVTKYADISELLAVQHNNHTTIRFSINTPRVIKNYEHRTSSLEDRIESAYNILNSGYKTGFIVGPVFLYENWKKEYEELLKKASDKLGDKELEFEIISHRFTTSAKNKILKVFPNTKLPMDDEARKFKFGQFGYGKYVYDKDDMQEIKEFFINNINLYFNKATIKYII
Protein: Steroid receptor RNA activator 1 (Zgc:86613) (Q6IQU0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSDRFVKPGNQEHGWNDPPQFSYGLQKDSGGQKRNILNKRVHAPQTTGSGSEIQSTPLAGQTPPRGINPPPMDGVTPPPACPRVPSDGAVEAVQSETEPRFEDVQESLYWALNACRPNVKKQVCDDVERRLKVFEDMWKTGKLSLLVKRRMLGLSQELKRKNWDAADEIHRDLMVDHVSEVSQWMVGVKRLIAEARSLKPEQISSCTDAGS
Protein: ADP,ATP carrier protein 2, chloroplastic (ADP/ATP translocase 2) (Adenine nucleotide translocase 2) (P92935)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- AT5g24690/MXC17_8)
- Dicarboxylate transporter 2.2, chloroplastic
- Plastidal glycolate/glycerate translocator 1, chloroplastic
- Inorganic phosphate transporter 2-1, chloroplastic
- Protein CLT2, chloroplastic
- D-xylose-proton symporter-like 3
- Folate transporter 1, chloroplastic
- Uncharacterized protein At5g13720)
- Sodium/proton antiporter 1
- Plastidic glucose transporter 4
Sequence:
MEGLIQTRGILSLPAKPIGVRRLLQPSHGLKQRLFTTNLPALSLSSNGHKKFQAFQQIPLGISVSHKERSRGFICKAEAAAAGGGNVFDEGDTAAMAVSPKIFGVEVTTLKKIVPLGLMFFCILFNYTILRDTKDVLVVTAKGSSAEIIPFLKTWVNLPMAIGFMLLYTKLSNVLSKKALFYTVIVPFIVYFGAFGFVMYPLSNLIHPEALADKLLATLGPRFMGPLAIMRIWSFCLFYVMAELWGSVVVSVLFWGFANQITTVDEAKKFYPLFGLGANVALIFSGRTVKYFSNMRKNLGPGVDGWAVSLKAMMSIVVGMGLAICFLYWWVNRYVPLPTRSKKKKVKPQMGTMESLKFLVSSPYIRDLATLVVAYGISINLVEVTWKSKLKAQFPSPNEYSAFMGDFSTCTGIATFTMMLLSQYVFKKYGWGVAAKITPTVLLLTGVAFFSLILFGGPFAPLVAKLGMTPLLAAVYVGALQNIFSKSAKYSLFDPCKEMAYIPLDEDTKVKGKAAIDVVCNPLGKSGGALIQQFMILTFGSLANSTPYLGVILLGIVTAWLAAAKSLEGQFNTLMSEEELEREMERASSVKIPVVSQEDAPSGETTSQLSEKSTPTGI
Protein: Acyl-CoA dehydrogenase family member 9 (D6RCD8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSGCGLFLRTTAAARACRGLVVSTANRRLLRTSPPVRAFAKELFLGKIKKKEVFPFPEVSQDELNEINQFLGPVEKFFTEEAYICLIKIFLLAVDSRKIDQEGKIPDETLEKLKSLGLFGLQVPEEYGGLGFSNTMYSRLGEIISMDGSITVTLAAHQAIGLKGIILAGTEEQ
Protein: Bone morphogenetic protein 2 (Q8MKC2)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
AELQVFGKHMPEALENNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVTQNASRWESFDVTPAVMRWTAQGLTNHGFVVEVAHPEDSHGASKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHRREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAIS
Protein: Anaphase-promoting complex subunit 5 (Cyclosome subunit 5) (Q9VZL2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Anaphase-promoting complex subunit 2
- Cell division cycle 16
- Cyclosome subunit 8
- Shattered
- Cell division cycle protein 27 homolog
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 13
- Anaphase promoting complex subunit 7, isoform A
- GEO10730p1
Sequence:
MILCLHFAGKSKIGFRGPKLTMNLFEELDTLDPSFKLEPPRIETPTAHKITVLILLKQYVINKKNCLDTGISMRTQRRRMFYMLVFKLIQEQDKSYNELHSLLTTGKYKLDTLMLESFEKAMSEFCAGSIEALFDFSEIQNIDEILNENYGISQFSMVGVYVRRVGVVLERLSFPEMMDMYKNVCSYYERGVRAAASGSRMAVAGGILHREETPPPNPITEKPEDPKPKKKVEAVARIAQERNPLSKWAPKQAKFFINKQSELLENNERKALPPLELQKKVQEIIHDLPLTTTPYFLGYMNQLRVRDYYNALSALHRALDRSPVRLMSQEKGYQYFCVNLAVLHATFGHRDEALAALRESIMLAQEHGDKRSLNLANTWYCLLRDELPLSAVQKSVQDANEVDGSLLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDNLTNRNNFADHASEALALRSAVWSAYGRHELAALYSQVLLTGRDRFGSGSAGLGSALASFALWLQLQGEPQLSKVLLHHAKQRFPRLPSAEGWMISQCHVVIQAGIYQCRWHDALKACDQLYLIDPSDSLFQRASIYVAKREFFNARRLLDKLAVQDNIPFLLRMRVQVLLGYCGMANGRFSSETTMLLLRVSEEMSEAQMDYELALVDLLLALQLLLLGMPQKAYQAIKRCMHDIHINGGLYERAKTDFVFVRCLLAVNQNDAEKRKAQLLKSQVILQRAAQSFKKLSAHAKVLDVYVFLAQRFNEFGDRNLRNKYAGEFRRYFTDHPIPREYLGSP
Protein: Hypersensitive induced reaction3 (Hypersensitive-induced response protein) (Q9M582)
Organism: Zea mays (Maize)
Interaction partners:
Sequence:
MGNLCCCVQVDQSTVAIREQFGKFDSVLEPGCHCMPWFAGKRVAGQLTLRLQQLDVRCETKTKDNVFVNVVASIQYRALADKASDAFYKLSNTRSQIQAYVFDVIRASVPKLHLDDAFEQKDEIARAVEEELEKAMSAYGFEIVQTLIVDIEPDEHVKRAMNEINAAARLRAAANEKAEAEKIVQIKRAEGEAEAKYLSGLGIARQRQAIVDGLRDSVLGFSVNVPGTTAKDVMDMVLITQYFDTMKEIGASSKASSVFIPHGPGAVRDIATQIRDGLLQGSSVAKH
Protein: Hemoglobin alpha, adult chain 2 (A0A8I6AI13)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MALSQTDHRLVLALWKKMGSNVGIYTTEALERTFLAFPSTKTYFPHLDLKPGSSQVKAHAQKVADALTLAAHHLDDLPGSLSALSDLHAHELRVDPANFQFFSHCLLVTLARHYPGDFSPEMHASLDKFLGHVTSALVSKDR
Protein: Somatotropin (Growth hormone) (P08998)
Organism: Gallus gallus (Chicken)
Function: Growth hormone plays an important role in growth control.
Subcellular location: Secreted.
Interaction partners:
- Growth hormone receptor
- Appetite-regulating hormone
- Prolactin
- Somatoliberin
- Prolactin receptor
- Uncharacterized protein.
- Neuropeptide Y receptor type 2
- Pancreatic polypeptide
- Glycoprotein hormones alpha chain
- Insulin-like growth factor 1
Sequence:
MAPGSWFSPLLIAVVTLGLPQEAAATFPAMPLSNLFANAVLRAQHLHLLAAETYKEFERTYIPEDQRYTNKNSQAAFCYSETIPAPTGKDDAQQKSDMELLRFSLVLIQSWLTPVQYLSKVFTNNLVFGTSDRVFEKLKDLEEGIQALMRELEDRSPRGPQLLRPTYDKFDIHLRNEDALLKNYGLLSCFKKDLHKVETYLKVMKCRRFGESNCTI
Protein: At1g73120 (F-box/RNI superfamily protein) (Q9CAS9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Emb|CAB82975.1
- Emb|CAB89385.1
- Eukaryotic aspartyl protease family protein
- Transmembrane protein
- At1g01170)
- Putative defensin-like protein 227
- At3g06890
- AT4g32020/F10N7_170
- Transmembrane protein
- Uncharacterized protein At2g30760
Sequence:
MATSTFSSRGAQTMNTMFVKPMLRKSIHKKSASHDIVRDTVKTEGSSSGEEVKTMRGFYGAGETSSPASSWVPHEGTGIYYPKGQEKVMQDVPPPPAGSHADELVNWFS