wanglab/gogpt-training-data huggingface dataset:
Protein: Cyclic di-AMP synthase CdaS (c-di-AMP synthase) (EC 2.7.7.85) (Diadenylate cyclase) (DAC) (O31854)
Organism: Bacillus subtilis (strain 168)
Function: One of 3 paralogous diadenylate cyclases (DAC) in this bacteria, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP) (Probable). Upon expression in E.coli leads to c-di-AMP synthesis. Overexpression of the hyperactive mutant (L44F) in the absence of c-di-AMP phosphodiesterase GdpP leads to growth defects in log phase (long curly cell filaments) that disappear upon sporulation; spore formation is normal, showing sporulation is insensitive to the excess c-di-AMP. In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.
Interaction partners:
- CdaA regulatory protein CdaR
- Cyclic-di-AMP phosphodiesterase PgpH
- Cyclic-di-AMP phosphodiesterase GdpP
- Cyclic di-AMP receptor A
Sequence:
MKAMRYEQISENAFKGKIQVYLEQILGDASLILKTLHEKDQCLLCELDDLGHVFQDMQGIASSFYLQSYIEEFTPAFIELAKAIKALSEHKHGALIVIERADPVERFIQKGTSLHAEISSSLIESIFFPGNPLHDGALLVRENKLVSAANVLPLTTKEVDIHLGTRHRAALGMSGYTDALVLVVSEETGKMSFAKDGVLYPLISPRT
Protein: Rbp1-like, isoform B (M9MS48)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- LD32469p
- RNA-binding protein 8A
- LD40489p
- RNA-binding protein Rsf1
- Eukaryotic initiation factor 4A-III
- Ribonucleoprotein RB97D
- Heterogeneous nuclear ribonucleoprotein K, isoform C
- FI21236p1
- Transformer-2 sex-determining protein
- Protein mago nashi
Sequence:
MPRYREWDLACKVYVGNLGSSASKYEIENAFSKYGPLRNVWVARNPPGFAFVEFEDRRDAEDATRGLDGTRCCGTRIRVEMSSGRSREGRGGGGGGGGGGGGSGGGGRGGGSGARAGGGGRAGDGGGRYRIKSSSSTTTSTTRTTTTTTSIIIIIMIIKRTTKKKEKTTTATTTRTSTTPLPSTTTTKRTTTTATTRTTSTTADPAPPITHISPTTTTTTATTTPPPCNNNLLCGPNQKFNKFDIFR
Protein: Amino acid transporter, putative (D6XEF7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLFLFHPFVPETLWVKEVPKSANRLQDAMSNSKQQQEVQTPNNLSNEPVQTEDNVKKGRNTFFTKVSLCVATVLPPGGIAASAFNMASTTIGAGIFGMPPAANSTGLIMGMFYLIFISSVTVFTMHNLSVAADRSGAPTFERATRALLGRGAAYVLAGIRALLGFSGCVAYVISVGDILSAILKGTNAPDFLKEKSGNRLLMAVVWACFMLPLTIPRHIDSLRYVSTFAVTFMVYFVIVIVVHSCMNGLSENIKNVSVTKSEDAEIILFNSGFQAIEGMGVFMFAFISQITAYEVYIDMKDRSVRKFVIAAIIANTLCCIMYIITAFFGYMDFGKTATSSILLMYDPVKEPAVMVGMIGVVIKLCVSYALVAMACRNALYDVVGKTADSLPFWKHCVSVITLSFLVLLLSIFIPKITTVFGIAGSVCGGSLGFVFPALLIMYSGGFTWQKVGPLYYITTYVVLLCGVFLIVFGTGSTILDTVRG
Protein: Notchless protein homolog 1 (A0A0A0MRH0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MAAAVPDEAVARDVQRLLVQFQDEGGQLLGSPFDVPVDITPDRLQLVCNALLAQEDPLPLAFFVHDAEIVSSLGKTLESQAVETEKVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR
Protein: Solute carrier family 13 member 3 (C9J7L4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLFGQKEVRKDPSQESEENTAAVRRNGLHTVPTEMQFLASTEAKDHPGETEVPLDLPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGWRKNKSEIRTNAEDRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRDPKFIPGWASLFNPGFLSDAVTGVAIVTILFFFPSQRPSLKWWFDFKAPNTETEPLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQ
Protein: Major urinary protein 18 (A0A0G2JTN2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKLLLLLLCLGLTLVCGHAEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGSMRVFVQHIRVLENSLAFKFRIKENGVCTEFSLVAYKTPKDGEYFVEYDGGNTFTILKTDYDRYVMFHLVNFKNGETFQLMELYGRTKDLSSDIKEKFAKLCVAHGITRDNIIDLTKTDRCLQARG
Protein: FHA domain-containing protein (Q580T9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Splicing factor 3B subunit 1, putative
- RNA helicase
- MI domain-containing protein
- RNA-binding protein, putative
- RNA-binding protein, putative
- PHD finger-like domain-containing protein 5A
- PRP8 protein homologue
- Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats domain-containing protein
- Uncharacterized protein
- Splicing factor 3A, putative
Sequence:
MERVTYARTGALRSTYAGLPVTKERLVTAAPAKWFPLLTTVPQRVLKSISDSDGVDGSLLGFLPIAFVFEELRKHLSDFTQHAAFLRAVLQWYHQTAGDTLESEIATDKVEIFQPYLPAYRLRVLKEGETVATFNDISRRAVTLMGKDRGINDIPLDHPSCSAQHAALEVNFVHRNSEPFQQRLHTLMQEEYRNINWSSPDEVGKLCAHALQLMREFGGDEDMWLMELQVVDLGSTNGTNLNGELLRPLERATVIEGDVLTFGYSTRKYLIVRA
Protein: Probable WRKY transcription factor 62 (WRKY DNA-binding protein 62) (Q9LZV6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histone deacetylase 19
- Regulatory protein NPR1
- Glutaredoxin-C9
Sequence:
MNSCQQKAMEKLLHGHGCANQLLIMDQTESDSSMEREDLAKSVLHCFSDALSILIDTNDHQDDQSNNSSPQDSSPVLESSRKPLHKRGRKTSMAESSDYHRHESSTPIYHDGFLWRKYGQKQIKESEYQRSYYKCAYTKDQNCEAKKQVQKIQHNPPLYSTTYFGQHICQLHQAYATFPIDTSDFEEHEGSHMIRFGHPNISFSSSTSNLRQHQNHQDRIKDEYMKPVIAEDWSPSQWMSSEVALAVEAFEFNPFWTSHDLSS
Protein: RNA polymerase sigma factor (G3XDC4)
Organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Interaction partners:
- RNA polymerase sigma factor-70 sigW, putative
- Type III secretion protein HrpJ
- RNA polymerase sigma factor sigW, putative
- Type 3 secretion system ATPase
- Type III transcriptional regulator HrpS
- Type III transcriptional regulator HrpR
- RNA polymerase sigma-70 family protein
Sequence:
MFQKIVILDSTQPRQPSSSAGIRQMTADQIQMLRAFIQKRVMNPDDVDDILQCVFLEALRNEHKFQHASKPQTWLCGIALNLIRNHFRKMYRQPYQESWEDEVHSELEGHGDVSHQVEGHRQLARVIQAIDCLPSNMQKVLEVSLEMDGNYQETANSLGVPIGTVRSRLSRARVQLKQQIDPFA
Protein: Long-chain-fatty-acid--CoA ligase (Q8SXR7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Bardet-Biedl syndrome 9
- Bardet-Biedl syndrome 1
- Bardet-Biedl syndrome 8
- BBSome complex member BBS4 homolog
Sequence:
MSENEKRPDLEDQDQDQNQEQAGGRKMEILLELNLKQKLATRLGTILLATVIFGAFCWDNALASLTLGAVVALLLRNPTFVFALVMTASRDLKAFQRFVALNIYLLRKDRGGFTVARCFQDQARRRPKKTCFVMDDRHLSFAEALEFSQKIAGYFSDRGLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGESLLHSIKVANAKALIVGSELLDVLVSLREKEQLDEVPIYQYTDDEVRGVAGHDLLPGAVDLVTALKTQKKLELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYMLKMSSDDVVYDPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGELCRYLLATSYSPDQQKHNLRLMYGNGLRPQIWSQFVRRFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSLYPVQVLRCDEYTGELLKDSKGHCIRCQPGQAGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNSGDMVVRDILGYFYFKDRTGDTFRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPHVEGKAGMAAIVDPERKVDMDYLSVVLRGSLPPYARPLFIRLLDEIPRTATFKLKKRELAKEAYDIGQLSDPIYYLNRDGIYRPLSQEQHELLRSGKAGL
Protein: Rhamnogalacturonan acetylesterase (RGAE) (EC 3.1.1.86) (Q5BAA2)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Plays a key role in the degradation of rhamnogalacturonan in the cell wall. Involved in degradation of pectin.
Subcellular location: Secreted {ECO:0000305|PubMed:22589326}.
Interaction partners:
Sequence:
MKSIALTSLSLLPSALAQTIYLAGDSTMASSTPGWGDYIADSVSVEISNQAIGGRSARSYTREGRFQAIADVLQAGDYVVIEFGHNDGGSLSNDNGRTDCPGDGDETCETVYNGVAETVLTFPAYIENAALLFLEKGANVLISSQTPNNPWESGTFSYTPNRFVGYAELAAQRAGVDYVDHGAYTASIFEALGADTVNSFYPNDHTHTNAEGSSVVADAFLKAVVCSGVALNDVLTRTDFDGECL
Protein: Protein phosphatase 1 regulatory subunit 1B (DARPP-32) (Dopamine- and cAMP-regulated neuronal phosphoprotein) (Q6J4I0)
Organism: Rattus norvegicus (Rat)
Function: Inhibitor of protein-phosphatase 1.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Cyclin-dependent kinase 5
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Protein phosphatase 3 catalytic subunit alpha
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
- 3',5'-cyclic-AMP phosphodiesterase 4B
Sequence:
MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPALLFRVSEHSSPEEESSPHQRTSGEGHHPKSKRPNPCAYTPPSLKAVQRIAESHLQTISNLSENQASEEEDELGELRELGYPQEDDEEDEDEDEEEDEEEDSQAEVLKGSRGTAGQKLTSGQGLEGPWERPPPLDEPQRDGNSEDQGEGRATQSEPGEEPRHPTPPESGT
Protein: Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Q52PJ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q62952}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q62952}.
Interaction partners:
- Cell division protein kinase 5
- Phosphoribosylglycinamide formyltransferase.
- Neuropilin-1a
- Uridine 5'-monophosphate synthase
- sphingomyelin phosphodiesterase
- Semaphorin-3D
- Dihydropyrimidine dehydrogenase [NADP
- Plexin-A4
Sequence:
MSYQGKKNIPKITSERLLIKGGRIVNDDQSFYADIYMEDGVIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHLQMPFRGTTTADDFTQGTKAALAGGTTMIVDHVIPEPGCSLLEAFDRWSKWADEKACCDYSLHVDITHWNDSVKQEVETLIKEKGVNSFQVYMAFKDLYQMSNTELYEVFTFLGEHGGIAQVHAENGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAASFVTSPPLSPDPTTPDYLNTLLASGDLSVVGSAHCTFSVAQKAIGKDDFTQIPEGVNGAEERMSIIWDKAVVTGKMDENMFVAVTSTNAAKILNLYPRKGRIAVGSDSDLVIWDTDAVRTITAKTHHSAAEYNVFEGMELRGAPMLVVCQGKIVLEDGNLHATSGTGRFIPCSPFPDFAYKRVKARKQLAILKAVPRGMYDGPVSEFSPMSRGGTPSASTRTSPTKVPVRNLHQSGFTLSGPEEAPIRPAGRRIVVPPGGRSNITSLS
Protein: Vacuolar protein sorting-associated protein 11 homolog (Q658K0)
Organism: Homo sapiens (Human)
Subcellular location: Late endosome membrane {ECO:0000256|PIRNR:PIRNR007860}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR007860}; Cytoplasmic side {ECO:0000256|PIRNR:PIRNR007860}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004630, ECO:0000256|PIRNR:PIRNR007860}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004630, ECO:0000256|PIRNR:PIRNR007860}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004630, ECO:0000256|PIRNR:PIRNR007860}. Cytoplasmic vesicle {ECO:0000256|PIRNR:PIRNR007860}. Early endosome {ECO:0000256|PIRNR:PIRNR007860}. Cytoplasmic vesicle, autophagosome {ECO:0000256|PIRNR:PIRNR007860}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000256|PIRNR:PIRNR007860}.
Interaction partners:
Sequence:
MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLLLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYELTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYIARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRFREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYLGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT
Protein: Protein MEI2-like 3 (AML3) (MEI2-like protein 3) (Q9SVV9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable RNA-binding protein that plays a role in meiosis and vegetative growth.
Interaction partners:
- Protein STRUBBELIG-RECEPTOR FAMILY 7
- Wings apart-like protein 2
- Protein STRUBBELIG-RECEPTOR FAMILY 1
- Sister chromatid cohesion 1 protein 4
- Meiotic recombination protein SPO11-1
- Uncharacterized protein
Sequence:
MNIPSGTFSRSDHFHASSDASLFSSSLPLIQHQNINPRDSYHQSVDEMASGLDHFSGGIGNMLDDGDSHPIGNMLPDDEEELFSGLMDDLNLSSLPATLDDLEDYDLFGSGGGLELETDPYDSLNKGFSRMGFADSNVDNVMPQNIFQNGVGSIAGEHPYGEHPSRTLFVRNINSNVEDSELQALFEQYGHIRTLYTACKQRGFVMVSYNDIRASRAAMRALQGKLLKKRKLDIHFSIPKDNPSEKDVNQGTLVVFNLAPSVSNRDLENIFGVYGEIKEIRETPNKRHHKFVEFFDVRSADAALKALNRTEIAGKRIKLEHSRPGGARRNMMLQMNPELEQDDSYSYLNHVESPLASSPIGNWRNSPIDHPLQSFSKSPIFGNLSPTKNIRYPEFSMKTASVNNDQEGRRFSHLDHLFSSSSYNNASHKASTFQQPQSFGSVSSFGSLNSHPSHVETLSGSEFLWGSPSSSAWPVNPFSSNRENHRFPYSAQNGSLHQLHHIGSAPSGFFPRSPETSSMGSVAFRGASGNMNAQRNLRETSSPNFKMLSAPRRSQLFTGNGSYLWPAATMVSIDDPLEDGSNQQFDSNGNQADIKIQFQLDLSKIMRGEDPRTTLMIKNIPNKYTRNMLLAAIDEKNSGTYDFLYLPIDFKNKCNVGYAFINMVSPKFTIALYEAFNGKKWDKFNSEKVASLAYARIQGKAALIAHFQNSSLMNEDRRCQPIVFDGSESKYPIIRENSQLEASNSTVSHPLVGENTHQS
Protein: Natterin-like protein (B5X1I2)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MATTLHLIGGGGGNSFEFHGMDNGATLKKIGVAVEGWQIKAVRAELTDGRVATFGNSHTFNEFQFDLGERITKLSLWGNGAGTRLGAIKFTTSKNRQFFEKMTSWPLKTEYTIDVGSGICLGLQGRSGSDIDSMGFLFINTIKSSVLTNMEYPTLSLFKPQVTPEYVKSLSHHNDTSLVQEESITYSKTLTKTSSWSVSNKIESTLNVSVKAGIPDLVEVTSGFSLTVGVEQSTSLQKTETITESDTINVKIPPGKTLDVEITVGKATIDLDYRATVKVTCMNGSQLVFPSNGIYTGVTYTSARVSTKER
Protein: hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Q8I5Y8)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Glyoxalase I-like protein GILP
- Lactoylglutathione lyase
- hydroxyacylglutathione hydrolase
- GDP-L-fucose synthase
- Bifunctional dihydrofolate reductase-thymidylate synthase
Sequence:
MRFLKTLFSLNCLASVGFYKKFACKNLFFENSFIRKDLHTYFIDKRKYFHLNKKDICTNTIIIPFYKDNYSYIFYDDKEEGIVVDPADYNIINDISKKENIKIKHVLCTHKHSDHNNGNQYYYEKNINVYGIKEYDNKYINQDISNLTHFQINNFKINIFLSNFHSKNQVSYLIENDNNKSKKNIFFTGDFLFISGIGKNFEQDNEDLYNSINKLKLLDKQNIYIFCGHEYTLDNLKFALTVDSTNKNLLSFYDHVVNSNKNYPTVPTLLEHEYLYNPFLRCDQNDVRKSIDLYAKKKNIKIQQESDYIVILRLMKDNFKAS
Protein: Methylglyoxal synthase (MGS) (EC 4.2.3.3) (P0A731)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
Subcellular location: Cytoplasm.
Interaction partners:
- Glycerol dehydrogenase
- NADPH-dependent aldehyde reductase YqhD
- NADH-specific methylglyoxal reductase
- Lactoylglutathione lyase
- 4-hydroxy-tetrahydrodipicolinate reductase
- Multifunctional CCA protein
- Lactaldehyde reductase
- Hydroxyacylglutathione hydrolase GloB
- Bifunctional ligase/repressor BirA
- Poly
Sequence:
MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK
Protein: Protein argonaute-2 (G5EGR6)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSGGPQYLPGVMNSTIQQQPQSATSSFLPSGPISSTSTSSQVVPTSGATQQPPFPSAQAAASTALQNDLEEIFNSPPTQPQTFSDVPQRQAGSLAPGVPIGNTSVSIGEPANTLGGGLPGGAPGQLPGGNQSGIQFQCPRRPNHGVEGRSILLRANHFAVRIPGGTIQHYQVDVTPDKCPRRVNREIISCLISAFSKYFTNIRPVYDGKRNMYTREPLPIGRERMDFDVTLPGDSAVERQFSVSLKWVGQVSLSTLEDAMEGRVRQVPFEAVQAMDVILRHLPSLKYTPVGRSFFSPPVPNASGVMAGSCPPQASGAVAGGAHSAGQYHAESKLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYRSMPVIEFIAEVLELPVQALAERRALSDAQRVKFTKEIRGLKIEITHCGQMRRKYRVCNVTRRPAQTQTFPLQLETGQTIECTVAKYFYDKYRIQLKYPHLPCLQVGQEQKHTYLPPEVCNIVPGQRCIKKLTDVQTSTMIKATARSAPEREREISNLVRKAEFSADPFAHEFGITINPAMTEVKGRVLSAPKLLYGGRTRATALPNQGVWDMRGKQFHTGIDVRVWAIACFAQQQHVKENDLRMFTNQLQRISNDAGMPIVGNPCFCKYAVGVEQVEPMFKYLKQNYSGIQLVVVVLPGKTPVYAEVKRVGDTVLGIATQCVQAKNAIRTTPQTLSNLCLKMNVKLGGVNSILLPNVRPRIFNEPVIFFGCDITHPPAGDSRKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIISDLTYMVRELLVQFYRNTRFKPARIVVYRDGVSEGQFFNVLQYELRAIREACMMLERGYQPGITFIAVQKRHHTRLFAVDKKDQVGKAYNIPPGTTVDVGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNNLTADELQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDREHDSGEGSQPSGTSEDTTLSNMARAVQVHPDANNVMYFA
Protein: Trinucleotide repeat-containing gene 6A protein (Q3UHK8)
Organism: Mus musculus (Mouse)
Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As a scaffolding protein, associates with argonaute proteins bound to partially complementary mRNAs, and can simultaneously recruit CCR4-NOT and PAN deadenylase complexes (By similarity).
Subcellular location: Cytoplasm, P-body {ECO:0000250|UniProtKB:Q8NDV7}. Note=Mammalian P-bodies are also known as GW bodies (GWBs). {ECO:0000250|UniProtKB:Q8NDV7}.
Interaction partners:
- Protein argonaute-2
- Protein argonaute-1
- Endoribonuclease Dicer
- Probable ATP-dependent RNA helicase DDX6
- CCR4-NOT transcription complex subunit 1
- Protein argonaute-4
- Protein argonaute-3
- 5'-3' exoribonuclease 1
- RISC-loading complex subunit TARBP2
- m7GpppN-mRNA hydrolase
Sequence:
MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSDNGTSTATSTNNNAKRATASNQQPPPPQQQQPQQEQQQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSAVTNQQPQNNGEVQNSKSQSDINHNTSGSHYENCQRGPVSSTSDCSTSCKNAVNDLLEKEAWPSAPGSDPELAPECIDADSASNSESERNITVMASGNTGGEKDGLRNSTGLGSQSKFVVGSSSNNVGHGSSTGPWGFPHGALISTCQVSVDAPESKPESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQNINSKVSGSSTHGTWGSLQETCEPEVSGTQKVSFSGQPQNITTETTGPNNTTNFMTSSLPNSGSVQNNELPTSNPGAWRVSTMNHPQIQAPSVMNGTSLSHLSNGESKTGGSYGTTWGAYGSNYSGDKCAGPNGQANGDTVNATLMQPGINGPMGTNFQVNTNKGGGVWEPGTVNSQSSPWGSGNGANSGGSRRGWGSPAQNTGTGLSSVEWNKLPSNQHSNDSANGNGKKLTNGWKSTEEDDQGSATSQTNEQNSVWAKAGGTVESDGSAESTGRLEEKVTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACTDKTSPNSNDTSSVSGWGDPKPTLRWGDSKGSNCQGGWEDDSAATGMIKSNQWGGCKEDKSTWNDSQKSKQGWGDGQKSSQGWSISAGDNWGESSRSNHWGEANKKSSSGGSDSDRSISGWNELGKTSSFTWGNNINPNNSSGWDESSKPNSSQGWGDPPKCNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATSKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNIPEASGRSDQQAQMHRLLPAASAVSSKETSSGSGWGEPWAEPSTPATTVDNGTSAWGKPIDSGPSWGEPITAASNASTWGSSSVGPQSLSKSGPKSMQDGWCGDDMPLPGSRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEDAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMERNPYFDKNGNPNMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSAPSANRQQQDQQGRPLSVQQQMMQQSRQLDPSLLVKQQTPPSQQPLHQPAMKSFLDNVMPHTTPELQKGPSPVNAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSMSVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINSLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDVNHWNGAGLSGANCGDLHGTSLWGTPHYSTSLWGPPSSDPRGISSPSPINAFLSVDHLGGGGESM
Protein: Pentatricopeptide repeat-containing protein At4g21170 (O49558)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Subtilisin-like protease SBT3.1
- Lysine-specific demethylase JMJ28
- Pentatricopeptide repeat-containing protein At1g74600
- Cysteine-rich receptor-like protein kinase 27
- AT4g21620/F17L22_80
- Pentatricopeptide repeat-containing protein At1g06270
- Proteinaceous RNase P 1, chloroplastic/mitochondrial
- Sugar transport protein 12
- B3 domain-containing transcription factor VAL3
- Putative pentatricopeptide repeat-containing protein At5g47460
Sequence:
MVLIHTSVGFFKRFSTSATPSTSSASDWKTQQTLFRVATEISSILLQRRNWITHLQYVKSKLPRSTLTSPVFLQILRETRKCPKTTLDFFDFAKTHLRFEPDLKSHCRVIEVAAESGLLERAEMLLRPLVETNSVSLVVGEMHRWFEGEVSLSVSLSLVLEYYALKGSHHNGLEVFGFMRRLRLSPSQSAYNSLLGSLVKENQFRVALCLYSAMVRNGIVSDELTWDLIAQILCEQGRSKSVFKLMETGVESCKIYTNLVECYSRNGEFDAVFSLIHEMDDKKLELSFCSYGCVLDDACRLGDAEFIDKVLCLMVEKKFVTLGDSAVNDKIIERLCDMGKTFASEMLFRKACNGETVRLWDSTYGCMLKALSRKKRTKEAVDVYRMICRKGITVLDESCYIEFANALCRDDNSSEEEEELLVDVIKRGFVPCTHKLSEVLASMCRKRRWKSAEKLLDSVMEMEVYFDSFACGLLMERYCRSGKLEKALVLHEKIKKMKGSLDVNAYNAVLDRLMMRQKEMVEEAVVVFEYMKEINSVNSKSFTIMIQGLCRVKEMKKAMRSHDEMLRLGLKPDLVTYKRLILGFK
Protein: ATP-dependent RNA helicase DHX15 homolog (EC 3.6.4.13) (Q7K3M5)
Organism: Drosophila melanogaster (Fruit fly)
Function: RNA helicase involved in mRNA processing and antiviral innate immunity (By similarity). Acts as an activator of the p38 MAPK cascade.
Interaction partners:
- Splicing factor 45
- Probable U2 small nuclear ribonucleoprotein A'
- LD21442p
- Septin-interacting protein 1
- 116 kDa U5 small nuclear ribonucleoprotein component
- Pre-mRNA-processing factor 17
- Uncharacterized protein, isoform D
- Cell division cycle 5, isoform A
- Pre-mRNA-processing factor 19
- Nucleolar protein 58
Sequence:
MSKRRIEVGETYGSKAKKDPEASSSSAAAAAGTVAQILGGFVPNKQPPTMNPLTNTPYSQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCLDHKPDWVIYNEFVLTTKNYIRTVTDVKPEWLCCLAPQYYDLNNFPQCEAKRQLELLQQRLETKQYQKGF
Protein: SD03057p (Q95R77)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNFADPVDHDDASNQSLDSSSRTVPAPVAPQIKLFKQQTAFQPSATPADLEHRYMAWNDVGIVTAHVEPSGDSSIDVEFHDASIHHALHISNYNQHNLASVSSGALALASNESSKLVVIALAAAGNKEWSLSLPDCESAEAVVATRFLVAVATSSSFLRIFTVMGTQREVLTIPGPMVAIAGHEHSLMVVYHSSAPSQTQQHLAAMLVNINGLSLRQEYLPVPLTPGRQLTWFGYSDTGSPSIADNMGLLQLYRRSSNAWFPICDTMKQSTSVSHNFFVVAVSEKRQIVQAVLCRGTSYPMTNPRPMLQELRMQIPLCDVEVEKSELEDALLRSSLMQMDGAEKMQKETAIKLFALACSSECETRARELIESIACTDLLQLAVKYATKRGRIHLSDRLCELLPQLEAVQEARKQQTLLGASGIAATIVLPMTPTSASQSGPKPKAIELSSAKRGTLKRLVNSPNMFKAAAASAASRPSTPDITPSPLDTQENIFGESESEVPMGKATDHRSPLNSVNPFAMKRKLGDTGVIFGSEKLKLAKK
Protein: 45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4) (Q9BRK5)
Organism: Homo sapiens (Human)
Function: May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Subcellular location: [Isoform 1]: Golgi apparatus lumen {ECO:0000250|UniProtKB:Q61112}.; SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm {ECO:0000269|PubMed:17442889}. Cell membrane {ECO:0000269|PubMed:17442889}. Cell projection, bleb. Note=Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs. {ECO:0000269|PubMed:17442889}.
Interaction partners:
- Protein S100-B
- Calbindin
- Parvalbumin alpha
- Calmodulin-1
- Calmodulin-like protein 4
- Calmodulin-like protein 5
- Calmodulin-like protein 3
- Calmodulin-like protein 6
- Calretinin
- Protein S100-G
Sequence:
MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHEEF