wanglab/gogpt-training-data huggingface dataset:
Protein: Utrophin (Q61636)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Postsynapse {ECO:0000256|ARBA:ARBA00034110}.
Interaction partners:
Sequence:
MQILRTLQKCGKLKMMAVVRTSLQKVVVLLHRLQRMAVSSPRYQKLCKDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHRLDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLASLEELIKWLNMKDEELKKQMPIGGDVPALQLQYDHCKVLRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPRRNPQSKTELTPEERAQKIAKAMRKQSSEVREKWENLNAVTSNWQKQVGKALEKLRDLQGAMDDLDADMKEVEAVRNGWKPVGDLLIDSLQDHIEKTLAFREEIAPINLKVKTMNDLSSQLSPLDLHPSLKMSRQLDDLNMRWKLLQVSVDDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRSISHNKVPYYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLLELNTTNEVFKQHKLNQNDQLLSVPDVINCLTTTYDGLEQLHKDLVNVPLCVDMCLNWLLNVYDTGRTGKIRVQSLKIGLMSLSKGLLEEKYRCLFKEVAGPTEMCDQRQLGLLLHDAIQIPRQLGEVAAFGGSNIEPSVRSCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTTSGEDVRDFTKVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETPITLISMWPEHYDPSQSPQLFHDDTHSRIEQYATRLAQMERTNGSFLTDSSSTTGSVEDEHALIQQYCQTLGGESPVSQPQSPAQILKSVEREERGELERIIADLEEEQRNLQVEYEQLKEQHLRRGLPVGSPPDSIVSPHHTSEDSELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPDSDSRINGVSPWASPQHSALSYSLDTDPGPQFHQAASEDLLAPPHDTSTDLTDVMEQINSTFPSCSSNVPSRPQAM
Protein: Bacteriocin carnobacteriocin BM1 (Carnobacteriocin B1) (P38579)
Organism: Carnobacterium maltaromaticum (Carnobacterium piscicola)
Function: Has antibacterial activity against Listeria and Enterococcus.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MKSVKELNKKEMQQINGGAISYGNGVYCNKEKCWVNKAENKQAITGIVIGGWASSLAGMGH
Protein: Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4) (Q9BYU1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Homeobox protein Meis3
- Homeobox protein Meis2
- Cartilage intermediate layer protein 2
- Homeobox protein PKNOX1
- Homeobox protein Meis1
- Homeobox protein PKNOX2
- Homeobox protein Hox-C9
Sequence:
MAAPPRPAPSPPAPRRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDNSIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLASLQPPPGGGCLQSQAQGSWQGATPQPATASPAGDPGSINSSTSN
Protein: Grancalcin (H7BXD5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
Sequence:
MQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI
Protein: Iodotyrosine deiodinase 1 (IYD-1) (EC 1.21.1.1) (Iodotyrosine dehalogenase 1) (Q6TA49)
Organism: Sus scrofa (Pig)
Function: Catalyzes the dehalogenation of halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine, 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine (By similarity). During thyroid hormone biosynthesis, facilitates iodide salvage by catalysing the oxidative NADPH-dependent deiodination of the halogenated by-products of thyroid hormone production, monoiodotyrosine (L-MIT) and diiodotyrosine (L-DIT). The scavanged iodide can then reenter the hormone-producing pathways (By similarity). Acts more efficiently on 3-iodo-L-tyrosine than 3,5-diiodo-L-tyrosine (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:15289438}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q6PHW0}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q6PHW0}.
Interaction partners:
- Methionine aminopeptidase
- Adrenodoxin, mitochondrial
- riboflavin kinase
- Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
- Succinyl-CoA:glutarate-CoA transferase.
- Corrinoid adenosyltransferase
- Cytochrome c oxidase subunit 3
- Pterin-4-alpha-carbinolamine dehydratase
- 4a-hydroxytetrahydrobiopterin dehydratase
- NADH-cytochrome b5 reductase 3
Sequence:
MFLLTPVLVAVVCILMVWIFKNADGATKRREEEPRARAEARPWVDEDLKDSTDVLQVEEDADEWQESEEEVEHVPFSHTRYPEKEMVRRSQEFYELLNKRRSVRFISNERVPMEVIDNVIKAAGTAPSGAHTEPWTFVVVKDPDVKHRIREIMEEEEKINYLKRMGPRWVTDLKKLRTNWIKEYWDTAPVLILIFKQVHGFAANGKKKIHYYNEISVSIACGIFLAALQNAGLVTVTTTPFNCGPRLRVFLNRPANEKLLMFLPVGYPSKEATVPDLPRKPLDQIMVTV
Protein: Transcription factor MYB2 (Myb-related protein 2) (OsMYB2) (Q10MB4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor involved in abiotic stress responses. Plays a regulatory role in tolerance to salt, cold, and drought stresses. Regulates positively the expression of genes involved in proline synthesis and transport, and genes involved in reactive oxygen species (ROS) scavenging such as peroxidase, superoxide dismutase and catalase during salt stress. Transactivates stress-related genes, including LEA3, RAB16A and DREB2A during salt stress.
Subcellular location: Nucleus {ECO:0000269|PubMed:22301384}.
Interaction partners:
Sequence:
MDMAHERDASSEEEVMGGDLRRGPWTVEEDLLLVNYIAAHGEGRWNSLARSAGLKRTGKSCRLRWLNYLRPDLRRGNITPQEQLLILELHSRWGNRWSKIAQHLPGRTDNEIKNYWRTRVQKHAKQLKCDVNSQQFKDVMRYLWMPRLVERIQAAAAGQQQQQEGGTDTPPLSWQHGGSDGLYESPELPAPDASCWPAEYCAAAGGAQSGGTPAPELSSTTAGSSSLSTDSGAGAQPSWPTQADGAEWFTTACDASSATGGVAMRDTELELAQPPCQGGQTWTTSESSLPGLTFPDLAVADFEIGGFDVDSFWTSMEDDQLWCPTQAAV
Protein: Putative E3 ubiquitin-protein ligase SINAT1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SINAT1) (Seven in absentia homolog 1) (P93748)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates. Mediates the proteasomal-dependent degradation of ATG6, a component of the autophagosome complex. Requires TRAF1A/MUSE14 and TRAF1B/MUSE13 to target ATG6 for ubiquitination and subsequent regulation of autophagosome assembly. Modulates directly the ubiquitination and proteasomal-dependent degradation of FREE1, a component of the ESCRT-I complex. Modulates directly the ubiquitination and proteasomal-dependent degradation of ELC/VPS23A, a component of the ESCRT-I complex.
Subcellular location: Endosome, multivesicular body {ECO:0000269|PubMed:32753431, ECO:0000269|PubMed:32786047}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:32753431}.
Interaction partners:
- TNF receptor-associated factor homolog 1b
- TNF receptor-associated factor homolog 1a
- Autophagy-related protein 13a
- Cytochrome c-type biogenesis protein CcmE homolog, mitochondrial
- Protein FREE1
- 26S proteasome non-ATPase regulatory subunit 13 homolog B
Sequence:
MAPGGSALKEALESNSTGVDYEVKMAKVEANSKPTKSGSGSIGKFHSSNGVYELLECPVCTNLMYPPIHQCPNGHTLCSSCKLRVQNTCPTCRYELGNIRCLALEKVAESLEVPCRYQNLGCQDIFPYYSKLKHEQHCRFRSYSCPYAGSECSVTGDIPTLVDHLKDDHKVDMHDGCTFNHRYVKSNPHEVENATWMLTVFNCFGRQFCLHFEAFQLGMAPVYMAFLRFMGDENEAKKFSYSLEVGAHSRKLTWQGIPRSIRDSHRKVRDSQDGLIIPRNLALYFSGSDKEELKLRVTGRIWKEE
Protein: Calcium binding protein 39 (A0A0G2JZH0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- STE20-related kinase adapter protein alpha
- Serine/threonine-protein kinase STK11
- STE20-related kinase adapter protein beta
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- Calcium binding protein 39-like
- Serine/threonine-protein kinase 25
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
- non-specific serine/threonine protein kinase
- Serine/threonine-protein kinase 24
- STE20/SPS1-related proline-alanine-rich protein kinase
Sequence:
MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRAAQQEA
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q38B10)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSTDAMIGRVCRTFGEAFAKDEATAKEQKKKYWIKRVLGSGATGTVLCAKRTSDGETFAVKVVDLEGMNEGDKNRAQAEVHCLMNCDFFSILKCHEDFAKKDPQNEVNVLMIALVLDYANAGDLRQEIKSRAKASRTFREHEAGLLFIQVLLALHHVHSRHMIHRDIKSANILLCSNGLIKLGDFGFTKMYSATVSDDVGKTFCGTPYYVAPEIWRRKPYSKKADLFSLGVLLYELLTLRRPFDGESMRDVMNRTLSGQYDPLPPETSPEMAEIVSLLLSSDPKQRPCSGKLLDMPICKLFMSGLLEIVQTQPGFEGPLRDVIPSDIRNIKQLLRAEKRSIVNQMDESYSAAISTAVLEGATSCSGLGDVTLYEGIIKKQSSDMSWKRRYLCIRAELENGEDLSVGKLPKFKSLHLVLAISKDTLQRQCIATPFTDLEDVFPVPSKYTGSNAPNVFAVVFVGGSRLLFQARGTPERDAWMQKIQEVLGIGDAE
Protein: L-amino-acid oxidase apoxin-1 (LAAO) (LAO) (EC 1.4.3.2) (Apoxin I) (P56742)
Organism: Crotalus atrox (Western diamondback rattlesnake)
Function: Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme. Shows activity on L-Leu. Exhibits diverse biological activities, such as hemolysis, edema, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation. Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation. These different effects are probably due to different experimental conditions (By similarity). In addition, this protein induces hemorrhage and apoptosis.
Subcellular location: Secreted {ECO:0000269|PubMed:9083096}.
Interaction partners:
Sequence:
MNVFFMFSLLFLAALGSCAHDRNPLEECFRETDYEEFLEIAKNGLTATSNPKRVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERVGGRVRTYRKKDWYANLGPMRLPTKHRIVREYIKKFDLKLNEFSQENENAWYFIKNIRKRVREVKNNPGLLEYPVKPSEEGKSAAQLYVESLRKVVKELKRTNCKYILDKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFGYEKRFDEIVGGMDQLPTSMYEAIKEKVQVHFNARVIEIQQNDREATVTYQTSANEMSSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCKKKFWEDDGIRGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDANFFQALDFKDCADIVINDLSLIHQLPKEDIQTFCRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPFKRIYFAGEYTAQFHGWIDSTIKSGLTAARDVNRASENPSGIHLSNDNEF
Protein: Pyridoxal 5'-phosphate synthase subunit Pdx1 (PLP synthase subunit Pdx1) (EC 4.3.3.6) (C6KT50)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by Pdx2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16339145}.
Interaction partners:
- Pyridoxal 5'-phosphate synthase subunit PDX2
- Pyridoxine biosynthesis protein PDX2.
- pyridoxal kinase
- Glyceraldehyde-3-phosphate dehydrogenase
- transketolase
- ribose-phosphate diphosphokinase
- ribose-phosphate diphosphokinase
- Phosphoglucomutase, putative
- Ribose-5-phosphate isomerase
- GMP synthase
Sequence:
MENHKDDAVLLKHGWCEMLKGGVIMDVKSVEQAKIAEEAGAIGVMVLENIPSELRNKEGVARSVDPSKVEEIKKCVSINVLAKVRIGHFVEAQILEELKIDMIDESEVLTIADEMHHIDKHKFKTPFVCGCTNLGEALRRISEGASMIRTKGEAGTGNIIEAIKHIRTVNNEIKYLCSLSDSEVYHFAKKINAPIDLVLLTKKLKRLPVVNFAAGGVATPADAAMCMQLGMDGVFVGSGIFESENPRKMAASIVSAVSNFNNPKILLDVSMNLGKAMCGSTRVSDKWKNKNEEHTKFLTPQ
Protein: T. brucei spp.-specific protein (Q385V5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPSDVVVVFFSFFLFFFCQHVKGKVSSRVFPFICFFFSLAFVLRFLRPIIPFVDSFRLLRFLFCFMFYVFIFICLMFQLPLCLYLCLCLCSGGSVFFFPFCCFFFFPPPSPPFDVVFSSLLILFLSSLSLSLSLCLSLHLSNFSYLTVGWTLPFFS
Protein: Defective proboscis extension response 3, isoform B (Defective proboscis extension response 3, isoform C) (Defective proboscis extension response 3, isoform D) (Q59E13)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Dpr-interacting protein eta, isoform B
- Dpr-interacting protein theta
- Uncharacterized protein
- Dpr-interacting protein alpha, isoform A
- Dpr-interacting protein epsilon
- Dpr-interacting protein beta, isoform C
Sequence:
MPAAIVIVKQHKEQQHQQHQQQHRQDQQDQKDPRAAKQICNINLCGFLRRSGADDVDVIEPRSPGHAADVDVAAAAAGATTSVAATAAAAAAATTRAAATTRAVIIIMALVVSIMQQQQQSLLWPFCNGLAAAAASTGQPDDSGDGPTLSTFLSSSQSQSPSPPAASASASSPSSFSSFAVAHGPQTEATNHTFKSLAFLDASFGSDLFAQTDAKRERSGAADEESQDADTSQSLPIFDFGMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQVNTEPKMSMAFQLNIIEISPDAKAVISGPPDLHFKAGSAIILNCLVQQPSVKDIGPIYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQLGDTLKSRLRISNAQTTDTGNYTCQPTTASSASVLVHVINDENPAAMQKSGACPCALGPLQLLLHLLLLPELLLLRAGLAAGN
Protein: Big defensin (RPD-1) (P86316)
Organism: Ruditapes philippinarum (Japanese carpet shell) (Venerupis philippinarum)
Function: Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro. Has antibacterial activity against S.aureus (MIC=9.6 mg/L), B.subtilis (MIC=76.8 mg/L), M.tetragenus (MIC=38.4 mg/L), E.coli (MIC=76.8 mg/L), V.parahaemolyticus (MIC=19.2 mg/L), and V.anguillarum (MIC=2.1 mg/L).
Subcellular location: Secreted {ECO:0000269|PubMed:14673509}.
Interaction partners:
Sequence:
AVPDVAFNAYG
Protein: UvrABC system protein B (Protein UvrB) (Excinuclease ABC subunit B) (A0A0E0TGM2)
Organism: Geobacillus sp. (strain Y412MC52)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_00204, ECO:0000256|RuleBase:RU003587}.
Interaction partners:
Sequence:
MEGRFQLVSPYEPQGDQPQAIAKLVDGLRLGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSCIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHCIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYISATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIHERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIRDVIRATYAAEETEMYEAKPAAAMTKQEREELIRKLEAEMKEAAKALDFERAAQLRDIIFELKAEG
Protein: Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (Q6PGW8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MACFFRRSAALQLAKACGQNEETLIPLISVAPVNKKQSVADLRVSVSHLLQSGAVRPDGDLQNTTHTLARQIRTDAVVEEIIPGRGVIHFRLNKLLLAQKLLDQLRSDPDGFGVKSEILRQLRVGRTLVEFSSPNIAKKFHAGHLRSTIIGNFIANLKKALGNEVIRVNYLGDWGMQFGLLGSGFERFGSQEKLRTQPLEHLFESSVGGCCVYLYGSAVCVRPQVYVQVNREAESDASVRSAAAHFFRRLEQSEEQALELWRHFREITIHEYKRIYQRLGVEFDHYSGESFHRAETQTVLDELRSRCLLKTSQKGTGVVDLSDKGDMSNYATLVRSDGTSLYITRDVAAALDRKQRFSFDEMIYVTDKSQTMHFQQLFRILQAMGHQWAGSCHHVAFGLVQGMSTRRGEVLFLEDVLEEAQSRMIHNMRQSRTSKELEDPELTAERIGISALIVQDFKGPLISDYRFEWDKVLQAQGDTGVFLQYTHARLCSLLRQQDCEISCSDFSPLTDSRSVSLLQHLLRYDEVLLQCATDLQPKHLVNFLMTLSHLVASAHRELPVKGSSEAVAQARLCLFSSVHSVLANGMRILGITPVDKM
Protein: Anaphase-promoting complex subunit 4-like WD40 domain-containing protein (Q18859)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
Interaction partners:
- Intraflagellar transport protein 122 homolog
- WD repeat-containing protein dyf-2
- WD_REPEATS_REGION domain-containing protein
- Tetratricopeptide repeat protein 21 homolog
- Tetratricopeptide repeat protein 30 homolog
- Clusterin-associated protein 1 homolog
- Intraflagellar transport protein 56 homolog
- CHE-2 protein
- Intraflagellar transport protein 52 C-terminal domain-containing protein
- TRAF3-interacting protein 1
Sequence:
MPPMLNVMANYNEKTIGKLTMSVFRKFNLGLPEHGQLHFAEWNYNSNYIACGGALGKLKVVKIGTDATDLNKSPNAATLVVNQALEGHNATVMNATWNENNQKLTTSDTSGLIIVWGMFNEQWCEEMINNRNKSVVVSICWNLEGTKIAIAYADGNVIVGTLEGNRIWNKELEIQLAACEWAPDGDMLIFGTADGKVSVFDDSGSHFLDIPMHCLEAEDLEQALAKKEHQKEEIVCLKYWSPTLKSKTILDEMERDFERKLEKDREVTGTAIFTNFPTKPPPKELPEHEKNTEPYQPVPPDRPRFVVAYARGMMQLMRSLNDPEPVVVSIPNFKITGAKWSPNGAFLAVCGNDSDKDEPTFSKIHFLSAYGHIVGYFQTNDSCITGICWESTGLRMAIAAAGTLLIGQIRPEFKWGSIEETIVYVYQKEELYQYGIMFYDYKTDEKTVKTVTHFENMAFYREHCVLINRQDDGVIPHYFCQLCNSIGTSLDYNVTTVRPKFACVNGICAVIASEDRYFIWHFVLPKFNSVQAGIHVPGKSGDYVLEEQQRTIEYGTKRLLGSKDEICALCIGDTFFMMALLSGGIYRVSLNDGVITNSYPVSPSINSIKLNCTFTRLAVIKLVEQVPFQFLLYEFDGDELKLIYTSDKRDVWDYEWDQNNSNMLALKDKQKILICDGNSILEQSSVNGSILLFQNLVVTAVNIEKILLTPENPTKTCIVEVMIKAKQDVMNLVNAMKLEEAIDYAERSPHSELWSMIANYAVFKHAFDCAEHAFVKLGDYAGVQLVKKLRNIQSNDLRNAEIYAYRDTLEEAKTAFLQADRRDLAVEMYKKVGDYASVYDLIRNDDDDEGKCDAFRNMAETHYEMMEWEEAAKAYSYCGDTANQIDCLIRGNLFGELEVLARTLSDDSEFMEVMGDAFTSRGMCDQAVECYLRRSLPQKALHACKELNQWQKAQFIADANHMENVEGLLGKFAVEMRGESDEKSLSALALYMRAGRHLDAAKIAFDIAKDRKSKYVPYEELKQCYVLGAVLVENHRQTIKELRKIDKHNFLEDALDDESGLSAEQSRILENTWRGAEAFHFMIMAQQHFFENRIKDALQTSLILSDYEEFLDPAEVHSMIALAAANVNQFGICSKAMMRLEAFEEFDDAEKEEMRNLSFRLFSENPPVNPNSAKVACSVCDAKIDPYDLQCSECQTKFPVCIASGRLILDNIFWLCPRCKHRAHQHEIPKYNCCPLCHDMESFRVP
Protein: Protein C2-DOMAIN ABA-RELATED 4 (C2 domain-containing protein) (AtC2) (GTPase activating protein 1) (AtGAP1) (Q9LVH4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity. Stimulates the GTPase/ATPase activities of YchF1, and regulates its subcellular localization. Promotes tolerance towards salinity stress by limiting the accumulation of reactive oxygen species (ROS). Promotes resistance to bacterial pathogens (e.g. Xanthomonas oryzae pv. oryzae and P. syringae pv. tomato DC3000) (By similarity). Binds liposomes in the absence of exogenous Ca(2+), but this activity is enhanced in the presence of Ca(2+) and generates membrane curvature.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25465408, ECO:0000269|PubMed:26719420}. Nucleus {ECO:0000269|PubMed:25465408}. Cytoplasm, cytosol {ECO:0000269|PubMed:23550829, ECO:0000269|PubMed:26719420}. Note=Localized mainly in the cytosol under NaCl treatment, but translocates to the plasma membrane upon wounding. {ECO:0000269|PubMed:23550829}.
Interaction partners:
- Probable polyamine transporter At3g13620
- Staphylococcal-like nuclease CAN1
- Rho GTPase-activating protein 1
- 16 kDa phloem protein 2
- Protein kinase superfamily protein
- Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1
- Obg-like ATPase 1
Sequence:
MTTACPARTSSLMDDLLGLLRIRIKRGVNLAVRDISSSDPYVVVKMGKQKLKTRVINKDVNPEWNEDLTLSVTDSNLTVLLTVYDHDMFSKDDKMGDAEFEIKPYIEALRMQLDGLPSGTIVTTVKPSRRNCLAEESRVTWVDGKLVQDLVLRLRHVECGEVEAQLQWIDLPGSKGL
Protein: N(G),N(G)-dimethylarginine dimethylaminohydrolase (DDAH) (Dimethylarginine dimethylaminohydrolase) (EC 3.5.3.18) (Dimethylargininase) (P71889)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA).
Interaction partners:
- Probable ornithine aminotransferase
- Probable cationic amino acid transport integral membrane protein RocE
- Probable ornithine aminotransferase
- Universal stress protein Rv2319c
- HTH-type transcriptional regulator Rv2324
- Polyamine aminopropyltransferase
- Probable endonuclease 4
- Conserved protein
- NAD
Sequence:
MENTQRPSFDCEIRAKYRWFMTDSYVAAARLGSPARRTPRTRRYAMTPPAFFAVAYAINPWMDVTAPVDVQVAQAQWEHLHQTYLRLGHSVDLIEPISGLPDMVYTANGGFIAHDIAVVARFRFPERAGESRAYASWMSSVGYRPVTTRHVNEGQGDLLMVGERVLAGYGFRTDQRAHAEIAAVLGLPVVSLELVDPRFYHLDTALAVLDDHTIAYYPPAFSTAAQEQLSALFPDAIVVGSADAFVFGLNAVSDGLNVVLPVAAMGFAAQLRAAGFEPVGVDLSELLKGGGSVKCCTLEIHP
Protein: Phospholipase SGR2 (EC 3.1.1.-) (Protein SHOOT GRAVITROPISM 2) (Q8W5R2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in vacuolar formation or function (e.g. formation of vacuolar membrane 'bulbs'). Required for amyloplast sedimentation in the endodermis during shoot gravitropism, which are thus acting as statoliths. Particularly important for the negative gravitropism leading to leaf movement observed in darkness.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:11826298}. Note=Detected in small organelles membranes.
Interaction partners:
- Protein transport protein SEC31 homolog B
- Protein transport protein SEC31 homolog A
- Protein transport protein SEC13 homolog A
- Protein transport protein SEC13 homolog B
- N-acylphosphatidylethanolamine synthase
- E3 ubiquitin-protein ligase SGR9, amyloplastic
- Probable lysophospholipase BODYGUARD 3
- DnaJ homolog subfamily C GRV2
- Patatin-like protein 5
- Protein transport protein SEC24 A
Sequence:
MEDRETHLGTREVNETSPDLLKNTPSNIARLEDVIEQCHGRQKYLAQTRSPSDGSDVRWYFCKVPLAENELAASVPRTDVVGKSEYFRFGMRDSLAIEASFLQREDELLSLWWKEYAECSEGPKLQVNSKKKSIETPSEASVSSSLYEVEEERVGVPVKGGLYEVDLVRRHCFPVYWNGDNRRVLRGHWFARKGGLDWLPIPETVSEQLEVAYRNKVWRRRSFQPSGLFAARIDLQGSSLGLHALFTGEDDTWEAWLNVDPSGFSGIVGYTGNGIKLRRGYAGSYSPKPTQEELRQQKEEEMDDYCSQVPVRHLVFMVHGIGQKGEKSNLVDDVGNFRQITAALAERHLTSHQLSTQRVLFIPCQWRKGLKLSGEAAVDKCTLDGVRRFREMLSATVHDVLYYMSPIYCQAIIDSVSKQLNRLYLKFLKRNPDYVGKISIYGHSLGSVLSYDILCHQHNLSSPFPMDSVYKKFFPDEESPPTPAKADKPCSSHPSSNFEPEKSDQLNNPEKITGQDNNTMAKEPTVLEHHDVIQEDPSLISDSVVANVGLERRGGQEDDHHDSSGAISSQDVPDGADCRTPDSPSCSQEQSWDKESVNSNNEERIKLLQDEVNSLRSKVAQLLSENARILSDEKAKTSVAPKELNNEKVQTEDADAPTSFTPFIKYQKLEFKVDTFFAVGSPLGVFLALRNIRLGIGKGKDYWEEENAIEEMPACRRMFNIFHPYDPVAYRVEPLVCKEYLPERPVIIPYHRGGKRLHIGLQDFREDFAARSQRIMNHFDSVRTRVLTICQSKSADNLDEMEETDDEKDDRSYGSLMIERLTGTRDGRIDHMLQEKTFEHPYLQAIGAHTNYWRDQDTALFIIKHLYRELPDGPNSPTESTEGDDSPKDSSRPHSWIDRREADYDDEELPLTFSDKQITRSFSAEAKKYLKKP
Protein: Myocyte enhancer factor 2B (B8ZZJ5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYASTDMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPEKPLQWPAEPLLHCNSRTPTGELPLPPRRPPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRLPLADGWPR
Protein: Aminopeptidase N (AP-N) (mAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Membrane protein p161) (Microsomal aminopeptidase) (CD antigen CD13) (P97449)
Organism: Mus musculus (Mouse)
Function: Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines (By similarity). May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization (By similarity). May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:8805662}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P15144}. Note=Also found as a soluble form. {ECO:0000250|UniProtKB:P15144}.
Interaction partners:
- Reticulon-4 receptor
- Cytosol aminopeptidase
- Glutathione synthetase
- Glutathione hydrolase 6
- Glutathione hydrolase 1 proenzyme
- Glutamate--cysteine ligase catalytic subunit
- Glutathione hydrolase 5 proenzyme
- Glutathione hydrolase 7
- Glutamate--cysteine ligase regulatory subunit
- Putative glutathione-specific gamma-glutamylcyclotransferase 2
Sequence:
MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSATAPTLPGSTSATTATTTPAVDESKPWNQYRLPKTLIPDSYRVILRPYLTPNNQGLYIFQGNSTVRFTCNQTTDVIIIHSKKLNYTLKGNHRVVLRTLDGTPAPNIDKTELVERTEYLVVHLQGSLVEGRQYEMDSQFQGELADDLAGFYRSEYMEGDVKKVVATTQMQAADARKSFPCFDEPAMKAMFNITLIYPNNLIALSNMLPKESKPYPEDPSCTMTEFHSTPKMSTYLLAYIVSEFKNISSVSANGVQIGIWARPSAIDEGQGDYALNVTGPILNFFAQHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRESSLVFDSQSSSISNKERVVTVIAHELAHQWFGNLVTVAWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSSPADEIKTPDQIMELFDSITYSKGASVIRMLSSFLTEDLFKKGLSSYLHTYQYSNTVYLDLWEHLQKAVNQQTAVQPPATVRTIMDRWILQMGFPVITVNTNTGEISQKHFLLDSKSNVTRPSEFNYIWIAPIPFLKSGQEDHYWLDVEKNQSAKFQTSSNEWILLNINVTGYYLVNYDENNWKKLQNQLQTDLSVIPVINRAQIIHDSFNLASAKMIPITLALDNTLFLVKEAEYMPWQAALSSLNYFTLMFDRSEVYGPMKRYLKKQVTPLFFYFQNRTNNWVNRPPTLMEQYNEINAISTACSSGLKECRDLVVELYSQWMKNPNNNTIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRNATLVNEADKLRSALACSKDVWILNRYLSYTLNPDYIRKQDTTSTIISIASNVAGHPLVWDFVRSNWKKLFENYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKADNSATGFGTGTRALEQALEKTRANIDWVKENKDAVFKWFTENSS