wanglab/gogpt-training-data huggingface dataset:
Protein: LD15974p (RNA-binding Fox protein 1, isoform E) (Q7YU08)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MYYPHMVQAGVAPFPGAPAGYAAAPNPGAAVVAAAAAAQQQQQQQQQQQQQQQQAQQQQQQQVAGGPPSAADSLSMAVAAAAAKQSADPVTQMKSGSEAAGSGNSNNNNTAGAGTGAPGAAGGLTTEYSSGGCGGGGASTANSVVVATSVSDVVNASLYMQQKSTVLIANEAAESQQSSAMQNAGGGGNTGGGGGGGGGGTPSSPLSNSPSSATASQAGGCGLTLNGSATEGSMSGDTSPVASGEPLLQTPPAHQQQQQQQQPLLCSSPTSMQSSGTSVTGSSIASGTLAATSSSGVGLLPTTGLDSIANGGAPTGCAVVPASTSQVIAHLNAAAAAASGIVSPSANVATSLSSALVPAQSVAAVAAASLDAKSQPKRLHVSNIPFRFRDPDLRAMFGQFGTILDVEIIFNERGSKGFGFVTFANSNDAERARERLHGTVVEGRKIEVNNATARVQTKKVTAVPNVCVQWPEAAVAAAMRGVAIQRGHVGVVGATPYHHPHHPHHHPALLAASAAAAQQQQQRQLAAAAVATAAVAQQQQQQQQAVVQQQQQQVAAAAQQQHQQQQQQQQQAVQQQQAVQQQQQHQQQQQQQQQQQHAAVAAAAAAASHPHMHAAHAHAHAHALGPQLAQLQAVAVPTAASNAAALQQSLAAAIQNPSGNPNAAAAAAAYAARLSAATGATQSPQTAAAAAAAASMAASANAANNAAALHGFAPVYYDPFLAAAASADPNLRFQAAKPVTEVPAAQPAAILNRRTVTTLNSNPHTINRIPVPQNVLATAPLLKTPLSQAQQQAYATAATTYTAVAARAAYGAAAAAAAQPALAGYATVAGYAREYADPYLGHGIGPVPGYGATMYRGGFNRFTPY
Protein: Kinase suppressor of ras 1 (A0A2R8Y5H9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDRAALRAAAMGEKKEGGGGGDAAAAEGGAGAAASRALQQCGQLQKLIDISIGSLRGLRTKCAVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNSYPRFSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPDISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSADRWRSRYYGKGRYGHPDFKSSCPILEEYINSSKVVPRFERFGLGVLESSNPKM
Protein: Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (DNA-binding protein p96PIF) (Parvovirus initiation factor p96) (PIF p96) (Q9Y692)
Organism: Homo sapiens (Human)
Function: Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
Subcellular location: Nucleus. Cytoplasm. Note=May be also cytoplasmic.
Interaction partners:
- Glucocorticoid modulatory element-binding protein 2
- Dehydrogenase/reductase SDR family member 2, mitochondrial
- Homeobox protein PKNOX1
Sequence:
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED
Protein: Acyl-CoA binding protein, putative (Q583J2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVEETLDEKFQRLSKTLGVKATRPRMSIQTKLDLYGLWHQATGGPVKTPKPSRVNVVASTKWNARKKYEKLSKDEAKRKFVELAEKVVPPSNL
Protein: Phosphodiesterase (EC 3.1.4.-) (A0A140VJR0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
Protein: Putative cation exchanger YDL206W (Q12424)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Putative cation exchanger.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MHKPLRWLITIAFYVSNVILIGYSLSSNGSISEFYLHSVVLIECFSLLGVVTSDCLTPSLSYISSNIFHISDRVSGMTLLALGNALPDITSTYQSMKSGVTSLAIGELFGGIFFLLTVVIGLMGCVATIQFQHDKSIETYTEESFDQNLSYDRSNYILDVGIFTFMLLVSGTFLADGRLYFWECIVMVLTYCCCAVYLIKSYKYPCEINDALEREVEIKKTVLANNHITVPNRFTLTTTSDITSTDDGIRYVRPLGDTQIDEDNAISLDPTRLPSKSLDNISRFNQGIPERRDLIRRRIRGYLRSHYHGWVRMTLQDLLNIWEKQNLFNNTVKSLSLPSDDTHLFTKASLDEEGRPLIRKRMNSLQPKDFYKYLSLRNGENSNALDTAISAPQNEYQTYYNEPTSLFLTVPQKKTSKKSLSCDRIPNLVRSNNIILNDEATRTQESTNALNSISDVIDNSLLQYERDDIILDRTLSLCSTKSRTAWHSFQLYNYLTDVSLEIGFFEFLSLLVTTPVSIILYLSIPSEISQTDHDLPLSYLQNIQLIASPIILNQLITNNFSFWLLILSLVIAILLYFKTRTIPNKFNSDIIFTVAFLLSLACLSKAVHIIVVTLTHWINVFNISETILGLTIFTWGNSIGDLVSNITFVKIGVLEIAIGACFGSPLLYFLFGVGFDGIMIMLGDKTGKIVSGRDSNILMHHIDFKVDKNLINTGVGILIAFLIFTVLIPLNDWKIDKKISIALLTLYIVVTCISVFLEVHQV
Protein: glycerol kinase (EC 2.7.1.30) (Q9WU64)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
Interaction partners:
Sequence:
MADAPKAVLGPLVGAVDQGTSSTRFLVFNPQTAELLCHHQVEIAQEFPKEGWVEQDPKAILQSVYECIEKACEKLGQQSIDISNIKAIGVTNQRETTIVWDKFTGEPLYNAVVWLDLRTQSTVENLSKSISVSNNFVKNKTGLPISTYFSAVKLHWLIENVRKVQKAIEDGRAIFGTVDSWLIWCMTGGINGGVHCTDVSNASRTMLFNIHSLQWDEELCDFFGIPMTILPRIRSSSEIYGLVKSGVLEGVPISGCLGDQSAALVGQLCLQDGQAKSTYGTGCFLLCNTGQKCVNSEHGLLTTVAYQLGRQEPVYYALEGSVAIAGAVVSWIKNNLPIIKSSSEIEKLAEVAGTSYGCYFVPAFSGLYAPYWDPSARGIICGLTQFTNKFHIAFAALEAVCFQTREILDAMNSDCGIPLTHLQVDGGMTANRVLMQLQADILCIPVMKPFMPETTALGVAMAAGAAEGVSVWSLDPKDLSSVQMEKFEPQINVEESEGRYATWKKAVLKSMGWVLTQSPDGRDPSIFSSLTLGFYVVSSMVILIGARYM
Protein: Maturase-related protein (Q2F964)
Organism: Oryza sativa subsp. indica (Rice)
Interaction partners:
Sequence:
RKKEGSKFRPLTVVPPIEKIMKEAIRMVPESIYDPEFPDTSHFRSGRGCHSALRRIKEEWGTSRWFLEFDIRKCFHTIDRHRFISILKEEIDDSKFFYPTQKQFSAGRLVGGEKGPDSVPNSVLLSALLGNIYLHKLDQEIGRIRQKHEIPLVVKIRSVLLRIGRRIDDQEKYGKEAGFNAPQDNRALIVGRVKSIQRKATFHSLVSSWHTPPTSTPRRRGDQKTPFVFPPSAALAAFLNKPSSLLCAAFLIEAAGLTPRAEFNGREGFNKNLAMRDLLKYCKRRGLLIELGGEAILVIRSERGLARKLAPFKSHSLLIRICYARYADDLLLGIVGAVFLLIEIQKRITHFLQSGLNLWVGSAESTTIAARSTVEFLGTVIREVPPRTTPIQFLRELEKRLRVKHRIHITACHLRSAIHSKFRDLGYSIPIKELTKGMSGRGRLLDAVQLAETLGKNGLKSPQVSVLWGTVKHIRQRSRGIPLLHSSGQSKVPSGVQQAVSRSGMSVLKTKLYTPFGRKAAGEGRGHWAGSFSSEFPIQIEAPIKKILRRLRDRGLISRRRPRPIHVASLTNVSDRDIVNWSAGIAISPLSYYRCCDNLYQVRTIVNYQIRWSAIFTLAHKHKSSARNIIPKYPKDSNIVNQEGGKTLAEFPNSIELGKLGLGQDPNNDGALNYMFNK
Protein: Mitochondrial inner membrane m-AAA protease component paraplegin (EC 3.4.24.-) (EC 3.6.-.-) (Cell matrix adhesion regulator) (Paraplegin) (Spastic paraplegia 7 protein) (Q9UQ90)
Organism: Homo sapiens (Human)
Function: ATP-dependent zinc metalloprotease. Plays a role in the formation and regulation of the mitochondrial permeability transition pore (mPTP) and its proteolytic activity is dispensable for this function.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:9635427}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase F, mitochondrial
- Non-selective voltage-gated ion channel VDAC1
- Mitochondrial inner membrane m-AAA protease component AFG3L2
- Spatacsin
- Maspardin
- Complement component C7
- Complement component C8 beta chain
- Complement C5
- Complement component C6
- Complement component C9
Sequence:
MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRALQSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKAPEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEETQQPPLGGEEPTWPK
Protein: Serine protease 23 (EC 3.4.21.-) (Putative secreted protein Zsig13) (O95084)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Pseudokinase FAM20A
Sequence:
MAGIPGLLFLLFFLLCAVGQVSPYSAPWKPTWPAYRLPVVLPQSTLNLAKPDFGAEAKLEVSSSCGPQCHKGTPLPTYEEAKQYLSYETLYANGSRTETQVGIYILSSSGDGAQHRDSGSSGKSRRKRQIYGYDSRFSIFGKDFLLNYPFSTSVKLSTGCTGTLVAEKHVLTAAHCIHDGKTYVKGTQKLRVGFLKPKFKDGGRGANDSTSAMPEQMKFQWIRVKRTHVPKGWIKGNANDIGMDYDYALLELKKPHKRKFMKIGVSPPAKQLPGGRIHFSGYDNDRPGNLVYRFCDVKDETYDLLYQQCDAQPGASGSGVYVRMWKRQQQKWERKIIGIFSGHQWVDMNGSPQDFNVAVRITPLKYAQICYWIKGNYLDCREG
Protein: Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Rotamase F) (P29117)
Organism: Rattus norvegicus (Rat)
Function: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (By similarity). Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial p53/TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:19228691, ECO:0000269|PubMed:8567677}.
Interaction partners:
- Non-selective voltage-gated ion channel VDAC1
- ADP/ATP translocase 2
- ADP/ATP translocase 1
- Cellular tumor antigen p53
- Cytochrome c, somatic
- Hexokinase-2
- Non-selective voltage-gated ion channel VDAC2
- Non-selective voltage-gated ion channel VDAC3
- Apoptosis regulator Bcl-2
- ADP/ATP translocase
Sequence:
MLALRCGPRLLGLLSGPRSAPLLLSTTRTCSDGGARGANSSSQNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTSKKIVITDCGQLS
Protein: Ring-exported protein 3 (Q8I2F7)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Small ribosomal subunit protein eS30
Sequence:
MQTRKYNKMLSKVETKQFIYILFFLCLYLNTFNYKYTTSYEGSSFRQLSEPVVEEQDLKKTNAESSHIEATTSQATTSQATTSQATTSQATTSQATTSQATSSQESDEQGLTAPSLNLEETQSNKVRNKIFNFPIPSAEGTVSKEFKNQPKTEYEKKLFEEWQHLNMFEHSNWVNITVQSCQVLVQGLTSLDDYDAKFKSWSAMVELLGEFRITLFNESNNMFEALLNELREARKENPNENLTPEEEEKWDLIKQTKLEKDIEWKIYQILTWKYWNLKEFPGVDIPDPSVPSLDFDATYDVLGDILEDDEDEEDDEDTAKPSTSSS
Protein: Possible transcriptional regulatory protein (Probably TetR-family) (P95103)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- DNA polymerase IV 2
- Transcriptional regulatory protein MoaR1
- HTH hxlR-type domain-containing protein
- Possible transcriptional regulatory protein
- Probable transcriptional regulatory protein
- Transcriptional regulatory protein EmbR
- Probable hydrogen peroxide-inducible genes activator
- Putative mycofactocin biosynthesis transcriptional regulator MftR
- Probable transcriptional regulatory protein
- Transcriptional regulatory protein
Sequence:
MSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARKLCGR
Protein: Appetite-regulating hormone precursor (Preproghrelin-2) (B3IYK2)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Growth hormone secretagogue receptor type 1
- Growth hormone secretagogue receptor type 1
- Ghrelin O-acyltransferase
- Insulin
- Insulin
- Insulin
- Leptin
- Somatolactin
- Insulin-like growth factor I isoform X1
- Growth hormone 2
Sequence:
MLLKRNTGLMILMLCTLALWAKSVSGGSSFLSPSQKPQGKGKPPRVGRRDIESFAELFEGPLHQEDKHNTIKAPFEMGITMSEEEFQEYGAVLQKILQDVLGDTATAE
Protein: Probably inactive leucine-rich repeat receptor-like protein kinase At5g58150 (Q9LVN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:14506206}; Single-pass type I membrane protein {ECO:0000269|PubMed:14506206}.
Interaction partners:
- At5g35480
- Cyclase-associated protein 1
- Protein SGT1 homolog B
- Protein SGT1 homolog A
- Mto 1 responding up 1
Sequence:
MRLSLWGSLLFFSFFVKHLTSLDPNTDAYHLSSFFSAMRLPNSPQAHTFSSLCSWPGVVVCDSSENVLHISASGLDLSGSIPDNTIGKMSKLQTLDLSGNKITSLPSDLWSLSLLESLNLSSNRISEPLPSNIGNFMSLHTLDLSFNSISGKIPAAISNLVNLTTLKLHNNDFQFGVPPELVHCRSLLSIDLSSNRLNESLPVGFGSAFPLLKSLNLSRNLFQGSLIGVLHENVETVDLSENRFDGHILQLIPGHKHNWSSLIHLDLSDNSFVGHIFNGLSSAHKLGHLNLACNRFRAQEFPEIGKLSALHYLNLSRTNLTNIIPREISRLSHLKVLDLSSNNLTGHVPMLSVKNIEVLDLSLNKLDGDIPRPLLEKLAMMQRFNFSFNNLTFCNPNFSQETIQRSFINIRNNCPFAAKPIITKGKKVNKKNTGLKIGLGLAISMAFLLIGLLLILVALRVRRKSRTWATKLAINNTEPNSPDQHDSTTDIKQATQIPVVMIDKPLMKMTLADLKAATFNFDRGTMLWEGKSGPTYGAVLPGGFRAALKVIPSGTTLTDTEVSIAFERLARINHPNLFPLCGYCIATEQRIAIYEDLDMVNLQSLLHNNGDDSAPWRLRHKIALGTARALAFLHHGCIPPMVHGEVKAATILLDSSQEPRLADFGLVKLLDEQFPGSESLDGYTPPEQERNASPTLESDVYSFGVVLLELVSGKKPEGDLVNWVRGLVRQGQGLRAIDPTMQETVPEDEIAEAVKIGYLCTADLPWKRPTMQQVVGLLKDISPNY
Protein: Uncharacterized protein (Q38CB2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGMRKKETIKKAHKPGVAKGLSYRRPWATFVPTLICFLLLNYLAFGTTVDEEGTDLVVPSGLGDNNTSSLSKLQLLFEDRLMRSLFRVGLFMFREMKVIQLVAVLAFVIHCGEAGLAAGICIRCKADRRTFGLYTVLTLLGGATQLGPLFEAEKDYLKDTTNITTKDDVSKKA
Protein: Vacuolar protein sorting-associated protein 45 (mVps45) (P97390)
Organism: Mus musculus (Mouse)
Function: May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
Subcellular location: Golgi apparatus membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Associated with Golgi/endosomal vesicles and the trans-Golgi network.
Interaction partners:
- Rabenosyn-5
- Syntaxin-16
- Vesicle transport through interaction with t-SNAREs homolog 1A
- Syntaxin-6
- 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial
- Endoplasmic reticulum-Golgi intermediate compartment protein 3
- Ras-related protein Rab-5A
- Vacuolar protein sorting-associated protein 18 homolog
- Vesicle transport through interaction with t-SNAREs homolog 1B
- Conserved oligomeric Golgi complex subunit 6
Sequence:
MNVVFAVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVEYLIQELRRPKYSIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNILGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLGECVKQVISKEYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKRPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNVKRLLQNPKVTEFDAVRLVMLYALHYERHSSNSLPGLIVDLRSKGVAEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVFIIGGATYEEALTVYNLNRTTPGVRIVLGGTTIHNTKSFLEEVLASGLHSRSRESSQATSRSANRR
Protein: S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase (Mba_SUMT) (SUMT) (EC 2.1.1.107) (Uroporphyrinogen-III C-methyltransferase) (Q46BL0)
Organism: Methanosarcina barkeri (strain Fusaro / DSM 804)
Function: Involved in the archaeal biosynthesis of heme. Catalyzes the methylation of carbons 2 and 7 of uroporphyrinogen-III (UROGEN) to yield precorrin-2. It does not catalyze the overmethylation of precorrin-2 to trimethylpyrrocorphin.
Interaction partners:
- Uroporphyrinogen-III synthase
- Precorrin-2 dehydrogenase
- Probable porphobilinogen deaminase
- Cobalt-factor II C20-methyltransferase
- Glutamate-1-semialdehyde 2,1-aminomutase
- Glutamyl-tRNA reductase
- Delta-aminolevulinic acid dehydratase
- Precorrin-3B C17-methyltransferase
- Adenosylcobinamide-GDP ribazoletransferase
- 4Fe-4S ferredoxin-type domain-containing protein
Sequence:
MSGNYGKVYLVGSGPGDPELLTLKARRLIDSAEVIVYDQLPGKAILDSMPASAEKINVGKYAGSHTMTQAEINEVLVQKAKEGKMVVRLKGGDPYVFGRGGEEAEVLVAEEIEFEVVPGITSAIAVPAYAGIPVTHRESTSMVTFITGHEDPTKEESGLDWETLAKFGGTIVILMGVKMLGRNAEELMKHGKAPDTPVAVIERGTRADQRVTVGTLANIASLAEERKVKAPAITVVGDVVHLHDILGEQRTGVDF
Protein: Surfeit locus protein 4 homolog (O74559)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P53337}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein rer1
- Protein transport protein gos1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Endosomal protein P24B
- Uncharacterized membrane protein C16E9.09c
- ER lumen protein-retaining receptor
Sequence:
MTSRSPFSTIPLSMNQDSYQTRTTVGIRKKTFSERACQFMEQAETFMAPFTPYMPLLGRFLIVATYFEDAIRIVTQWPEQVSYMRDYRRFRFGTAPLLLFVCVVLMLVGSTLVVFKKRQAYAIGSLLFVTLLQAFAYGLITSGEMFFRNMSVIGGLCLVASDTFIHRRINRFAGLPAVSEHNKRTYFQLAGRVLLIFMFLGLLAKEGSGISWTRILVHILSVTACAMVVIGFKAKFFAAVLVLILSVANFIINSFWSVPRESPYRDFYRYDFFQTLSIVGGLLYLVNTGPGKFSVDEKKKIY
Protein: ERCC excision repair 6 like 2 (H0Y3T7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPEFLLRSMKKEPLSSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTVLHGNRKDNELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEVMKALKCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSGTYFKKQFSDPVEHGQRHTATKRELATGRKAMQRLAKKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVTLILQSSEPCTCRSGQKRRNCCYKTNSHGETVKTLYLSYLTVLQKVANHVALLQAASTSKQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNRDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERLKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQIYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGIHNLFKFRSQGSCLTKDILEREGQVEAGIMTATTWLKEGPPAHKLEMPRQPDCQECRGTEQAAEPLAKEACDLCSDFSDEEPVGATGIKTAKNKAPDSSKASSSPGQLTLLQCGFSKLLETKCKAVEDSDGNTASDDESSDEQPTCLSTEAKDAGCEKNQDSLGTSKHQKLDNILNPKEKHIFYKSEKILEQNISSKSDEKKIKNTDKHCILQNVTESEDSDVICPTQYTTERFPDNSIRFKPPLEGSEDSETEHTVKTRNNDNSRNTDDKRNGIISKKLSPENTTLKSILKRKGTSDISDESDDIEISSKSRVRKRASSLRFKRIKETKKELHNSPKTMNKTNQVYAANEDHNSQFIDDYSSSDESLSVSHFSFSKQSHRPRTIRDRTSFSSKLPSHNKKNSTFIPRKPMKCSNEKVVNQEQSYESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAAHDVFELKQFSQLPANIAVCSSKTYKEKVDADTLPHTKKGQQPSEGSISLPLYISNPVNQKKKKVYHTNQTTFIIGETPKGIRRYIVSDNTILEE
Protein: 20S-pre-rRNA D-site endonuclease NOB1 (EC 3.1.-.-) (NIN1-binding protein) (Pre-rRNA-processing endonuclease NOB1) (Q08444)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. In association with NIN1, may promote the recruitment of the proteasome to the ribosomal subunits stalled in maturation.
Subcellular location: Cytoplasm. Nucleus, nucleolus. Endoplasmic reticulum.
Interaction partners:
- Protein LTV1
- Essential nuclear protein 1
- Pre-rRNA-processing protein PNO1
- Serine/threonine-protein kinase RIO1
- Ribosome biogenesis protein TSR1
- Serine/threonine-protein kinase RIO2
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS2A
- Small ribosomal subunit protein uS19
Sequence:
MTENQTAHVRALILDATPLITQSYTHYQNYAQSFYTTPTVFQEIKDAQARKNLEIWQSLGTLKLVHPSENSIAKVSTFAKLTGDYSVLSANDLHILALTYELEIKLNNGDWRLRKKPGDALDASKADVGTDGKQKLTEDNKKEEDSESVPKKKNKRRGGKKQKAKREAREAREAENANLELESKAEEHVEEAGSKEQICNDENIKESSDLNEVFEDADDDGDWITPENLTEAIIKDSGEDTTGSLGVEASEEDRHVALNRPENQVALATGDFAVQNVALQMNLNLMNFMSGLKIKRIRNYMLRCHACFKIFPLPKDGKPKHFCASCGGQGTLLRCAVSVDSRTGNVTPHLKSNFQWNNRGNRYSVASPLSKNSQKRYGKKGHVHSKPQENVILREDQKEYEKVIKQEEWTRRHNEKILNNWIGGGSADNYISPFAITGLKQHNVRIGKGRYVNSSKRRS
Protein: Kinesin-like protein KIF1C (O35071)
Organism: Mus musculus (Mouse)
Function: Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}.
Interaction partners:
- KIF-binding protein
- Kinesin light chain 2
Sequence:
MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSVEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVNVNQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRSHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADLQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAVINEDPNARLIRELQEEVARLRDLLMAQGLSASALGGLKVEEGSPGGVLPPASSPPAPASPSSPPPHNGELEPSFSPSAEPQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDVDIKLTGQFIREQHCLFRSIPQPDGEVMVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGEDSDKRSCEESWRLISSLREQLPPTTVQNIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPEGPGDAWRAVARDVWDTVGEEEGCGGGGGGSEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLTQDLEDDNDESGLVTWAPPEGPEAVEETVPNDHSPAVRPTSPPLSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGAGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPAPQPPEEVTVPPAPPNRRPPSPRRPHRSRRNSLDGGSRSRGGGSTQPEPQHLRPQKHNGYPQQPQPSPAQRPGPRYPPYTTPPRMRRQRSAPDLKESGAAV
Protein: 1,2-diacylglycerol 3-glucosyltransferase (Glycosyltransferase LafA, responsible for the formation of Glc-DAG (EC 2.4.1.-)) (Glycosyltransferase family 4 protein) (X5KCU9)
Organism: Streptococcus agalactiae
Interaction partners:
Sequence:
MRIGLFTDTYFPQVSGVSTSIRTLKEGLEKEGHEVYIFTTTDRNVKRFEDPTIIRLPSVPFISFTDRRVVYRGLISAYRIAKDYELDIIHTQTEFSLGLLGKLVAKALRIPVVHTYHTQYEDYVGYIAKGKLIKPSMVKYIMRTYLSDLDGVICPSRIVLNLLDGYGVKIPKQVIPTGIPVENYRREDISEETIKNLRTELGLADNDTMLLSLSRVSFEKNIQAILMHLSAVVDENPHVKLVIVGDGPYLSDLKELVHSLELENSVIFTGMVEHSQVAIYYKACDFFISASTSETQGLTYIESLASGRPIIAQSNPYLDDVISDKMFGTLYKKESDLADAILDAIAETPKMTQEAYEQKLYEISAENFSKSVYAFYLDFLISQKASVKEKVSLTIGNKDSHSTLRFVRKAVYLPKKVFTFTGRASKKVVKAPKRRISSIRDFLD