Protein: Protein NO VEIN (Protein EMBRYO DEFECTIVE 2597) (F4JTS8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protein required for cell fate determination during embryogenesis. Mediates auxin-dependent coordinated cell-fate specification and patterning in embryos (e.g. cotyledon outgrowth and separation), shoots and roots (e.g. leaf vascular development, cellular patterning and stem cell maintenance in the meristems). Required for provascular PIN1 expression and region-specific expression of PIN7 in leaf primordia, cell type-specific expression of PIN3, PIN4, and PIN7 in the root, and PIN2 polarity in the root cortex.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:19880797}. Note=Accumulates in speckles within the nucleus and the nucleolus. {ECO:0000269|PubMed:19880797}.
Interaction partners:
Sequence:
MQGNHDGSWSLHPSTNNGSGRANGNININTVPGGGYLPQANPVFPNFNQPIRYPIPQFPANFYRPNFPDFSLGNPNFQPHQNLNFLHQQIPHQYGSAANHFLQNHNQNSFSFPPQSIPNNDISISQNHGAFENSSLKRRRQEEVVQVTDVVPKSNFASGESANNSFSVSLPIPIATDDSGVSRVHGEKSSGKPKRKVDVLRIDKAVNKTRKLFVAAGESVSSTRVSRAVLEELQADSWRSLGVQMQDVPSLRQLMAIEGKINAFIHCFVGARRIVTLHDLEVAICRNEFVDSFDDLELGPLLQHPLVLLYFPSISSSTGPVKITSEEIISFLDSYLHTYMTEDVKLDEFLNFVASQKSVTSKEKLGVRIQSLRMYVSFILDAKRQEGETLKVLLTELHQKYHIPSSKKQQRDKSLTVSERADSFALHHKDYCGKHIRFDSSSSDENDNVYEVRNLNSSDHINSCPYPSVAEEMKRLGGSNKKRKGERRNHEKSDSSKLLRKSPSKLQGHAKQEIPKLADDSEAKKVFSVDEADFTLSEGDLRLFISTWKDTCKELSISTFVEKMLSFYNLGGSEGRAQIKRAKAMSSFPFVGLLNVAVTSLRRGMWDSIYDNFQMTSLSDTTNTGSGNQVGEINPIENSELSKTQHVMPPTHCNTVEEIIRRLSLYFEHDLSGAKHIGIFRKLQTCENLLAEQFQVQDFESLGWGGFFAFLEKHMLLLPTQLQRFLSRELQEEFPLEVHVNENLLTLLLSQASEFSSDKVLSRQTLARLVAEQFPSISFKVVGRDSEENFSEIIGKKKSSSKCVLFSATLLGAENSLTSKYLEESLTVGNDTEARSTTLNAVASKEVLDVLLRVPLLSDLNSWCHWDLRYAPQFGPLMGCLNEINSTDLLCLVTRDGKIIRADPSATADSFLEAALQGSAYRTAAQLLSLISLNGRTHLPFSLLKCYAKRAFEVFFYNYSEEMELNDRNSLVQMHGPEKLSTSFDKVIVVGEKAKVAKRDYAASKFLLDCLGYLPGEFRSLVVDILLPGLRSVVKDAPTRVLSACEQTEQRIMLHDAGLLLGIVEWISDYHKFCSSCSPNSSIVENASSNLDSGAGFVQNELEDPVQTKQRCMIVSEKSCEYKEEPHESCHTFGGSGILCDSVGEAFTQTAPEFYDNRASVIDSIRRDEFGLDLTSSGSEMSMLQKQHARLGRALQCLSQELYSQDSHFILELVQNADDNKYPEHVEPTLTFILQKTGIVVLNNECGFMPENIRALCDVGQSTKKGSGGYIGKKGIGFKSVFRVSDAPEIHSNGFHFKFDISEGQIGYILPTVVPPHDIESLSSMLSGRALHLKDAGWNTCITLPFRAIDSERTTVNHIEPMFSDLHPSLLLFLHRLQCIVYRNVLDDSLLVMRKEVVSKNIVKVSCGENSMTWFVASEKLKATNLRDDVQTTEISIGFTLDMLEDGTYRSCMIQEPVFAFLPLRTYGLKFIIQGDFILTSSREDVDEDSPWNQWLLSEFPGLFVDALRSFCSLPSFTQNLGKGVSSYMQLVPLVGEVHGFFSSLPRSIISRLRTTNCLLLEGDGEEWVPPCKVLRNWNEKIRVLLKDGLLQEHLALGFLDKDIVLSDSLSRALGIEDYGPKTLVQILSSLSHKNGCLQSMGFTWLSSILTELYLLFRSSGHGNVELGIDKSLIDDLHKIPFIPLSNGKFTSLDEGAVWLHHDTTGLDLGDVFEAFPVLYGNLRTIDHSLLLASSVDEKSSVDDLVNMLCAIGVQKLSAHEIVKAHILPAFEARSTGAVDGLMVDYLCFVMTHLRSGCHICLKERKYIISELRSKALVLSNYGLKQLGEGSIHFGEEYGNQVNMKKLTKNLDISWHVVDGTYLKHPASKFYACGLKEWREFFQEIGIADFVQVVQVEKSIAEFYSVSHCEKYDINLLSPDLTVKDWESPELVDLLSLLHKSNGRKGCKYLLEVLDRLWDDCYYDKTTVNYNSGTHGIIRSSESSFMRVICDSLWIVSSMDSKLHLSKDLYHDCDDVQSILGMNAPYAVPTVTSVKLLSDIGFKTKVSLDDALEVLESWVHCGDSFKSSISQITRFYKYLWNEMADSKQKITEKLHTLPSVFVPHGIASRQNDMISGIFLSLDDVYWNDSAGVLDEIKEISSQISSVVEPLRRKTLGNIYPGLHDFFVNGCGVPETPSFQEYLKILGQFAHNVSPSSAAKAVFKIFLKWSDDLNSGKSSEDVIHFKERLSELEYTVLPTENDKWVSLHSSFGLVCWCDNEKLKKRFKNKDKIEFISFGENDDEGQEVLQTKVSGLMHSLGIPSISEVVKREAKYEGLQDNTVTVSLVNWALPYAQRYIFTLHHEKYTQTKKTVHSQVKRLQVFVVDKLSYRNVIPQYGISSKKEFKCSSLLQDKALYTTPSLDSHSLFMELSRLFFNGVPDLHLANFLHLIKTMAESGLSEEQMESFILNSQKVHQVPDGEEIWSLKSAVKAKKKAGISLSWLPSSSKTRHGSSKTNTDDSKQELDTSSSKEDVTEALEEKIPIEMTNTNLVSGYDNCAGTSSRASEPNPLHSMHMISGSTSGNQAAMHLNPNLPHEWNNSFTANFSDRDQLHTGTPWAAQAQQTGRKGEEIAYRYFVAKYGNEALVKWVNDQSETGLPYDLMIENRGGKKEYVEVKATVSTRKDYFNLTVREWQFANEKGESYIIAHVLLGNSNAILTQHRNPVKLCQEGHLRLLVLMPNQRNEVNVTF