wanglab/gogpt-training-data huggingface dataset:
Protein: Cell division control protein 2 homolog 2 (EC 2.7.1.-) (Q57TX3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- GP-PDE domain-containing protein
- Cyclin-dependent kinases regulatory subunit
- Serine/threonine-protein kinase, putative
- Trypanosome variant surface glycoprotein B-type N-terminal domain-containing protein
- Protein kinase, putative
Sequence:
MQVQVQEGQTACDGSLRPLPSAGPASFVPRSLRPAPLRGTSTPDRYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRIPLIVNDGGVPSTAVREVSLLRELNHPYVVRLLDVVLHEAKLLLIFEYMEQDLQGMLKQRNTAFVGGKLRRIMFQLLLGLHECHSRRFVHRDIKPSNILIDRKESVVKLADFGLGRAFRVPLQTYTTEVMTLWYRAPEVLLGDKQYLPAVDVWSMGCVFAELARRRSLFAGDTAINQLFSIFQLLGTPTEATWRGVTSLPHHNVNFPRWTAKPLRTAVPALDDDGVDLLRRMLCYNPRERITAYEALQHSYFDEVREEEVEKLMRFNGA
Protein: Beta-defensin 124 (Beta-defensin 24) (DEFB-24) (Defensin, beta 124) (Q8NES8)
Organism: Homo sapiens (Human)
Function: Has antibacterial activity.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Beta-defensin 125
- Beta-defensin 135
- Beta-defensin 128
- Beta-defensin 127
- Beta-defensin 134
- Beta-defensin 114
- Beta-defensin 123
- Beta-defensin 116
- Beta-defensin 129
- Beta-defensin 113
Sequence:
MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
Protein: 1-acyl-sn-glycerol-3-phosphate acyltransferase 3 (EC 2.3.1.51) (Lysophosphatidyl acyltransferase 3) (Q9SYC8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. Has preference for C-18-CoA substrates compared to C-16-CoA substrates.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- 1-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic
- Lysophospholipid acyltransferase 1
- Lysophospholipid acyltransferase 2
- Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4
- Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 5
- Triacylglycerol lipase SDP1
- Glycerol-3-phosphate acyltransferase 9
- Triacylglycerol lipase SDP1L
- Probable glycerol-3-phosphate acyltransferase 3
- 1-acyl-sn-glycerol-3-phosphate acyltransferase 2
Sequence:
MKIPAALVFIPVGVLFLISGLIVNIIQLVFFIIVRPFSRSLYRRINKNVAELLWLQLIWLFDWWACIKINLYVDAETLELIGKEHALVLSNHRSDIDWLIGWVMAQRVGCLGSSLAIMKKEAKYLPIIGWSMWFSDYIFLERSWAKDENTLKAGFKRLEDFPMTFWLALFVEGTRFTQEKLEAAQEYASIRSLPSPRNVLIPRTKGFVSAVSEIRSFVPAIYDCTLTVHNNQPTPTLLRMFSGQSSEINLQMRRHKMSELPETDDGIAQWCQDLFITKDAQLEKYFTKDVFSDLEVHQINRPIKPLIVVIIWLGFLVFGGFKLLQWLSIVASWKIILLFVFFLVIATITMQILIQSSESQRSTPAKRPLQEQLISA
Protein: GILT-like protein 1 (Q95RA9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the immune response to bacterial infection.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MSHKIAAVCLLMSCLIATAYSAAKVPISIYYESLCPDSAKFITEQVYPAVKGELRDVVELTFVPFGKSQFVTQGSEVTFTCHHGPNECYGNKVHACAIEHIQANSYQVEYTRESLTMDFINCLMKAGKNFPDNVYPGQRCASENHINNWENIKTCANSTEGSVLLRKAGESTMRLKEPLTSVPTILFNEQFDKKVNDRAQVNLVGTICQYVSAPQPRICNQHNGASTPSLASVSAILSSLLGLWFIRSFY
Protein: Sterile20-like kinase, isoform F (EC 2.7.11.-) (B7YZQ1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFINRNLDAKPIKDLLLEYKAEVVEEVVDDETEEPRNSALQLDLDDDSASLQSQDIDKLPGTPTSILRDAKEQSQPSSSLPIAAAATAAAAATTTTKATTPDRPNHTKDDNAEAAAQQPPHTKVPAPAPPSSQQTPPPQVQQPPTPPAQPTAAVLQKKPEDVAAVAETSEKTESDKKHFVKKGKAPPPPSPLGLANAKPAASDSQTSPKKLATPEPTSPVTTAIEVAIGQEAMEPKPQPPSPTASSIVSVQSVASSSSSGSVSNAVLSSSTSLITINSDPPTPHHHQPLPPQPQHLILPNSLESVSQITVVTSTHPPVIIDNSVMPPQNEVIIVSNDMNKSTHLHESSTDDDFPSLDDSLGDATTPPHKQSSMILAVNEPAGVVPAPPSQPQTSSTVHARKLDESEVLIVSPSYADDDSAYNTASGSHSHDHSDHLMDTSHVSVVTVGDEGVKVKDSSNELVKRQPNGVGIVPEDVNIIVNRFKQEKRSPDSSLSENGSVRGRRGIEVLVGGSGGSDVDSIGTNTSQESRHETDHNNKQQYPAAALMPPPPPSLTNNHNHETIDEEEEVVIRPKARVPAVVKSANAQGLTKEEIELRNLRKKTRKRTRKFEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRISTNLDPEIERDRLKKFQEQEKKRYMQEERRFEVKHQKQLEELRATRESAIKELEQLQNEKRRALVEHEHSKLSEIDERLKGELREWREQLVPRKQELNRQIKLAIDQHEKRFGLVTNREEFEDQEVKLPAHLRNIYNERSSRILPRNTFIDPQNMPRSRSSLLMMGGGGNRLSNFRGSAPDLSRSVPNTPIMHKQQRSQMIGDQVLEEDEEQMLSEQMKRASVATLPAQNQLRLITQLPANELVKVVTSTPPLNSAEDVNSKPSMSTFRGSTPPKTPDDLGLVTNRFSRLDTKAAAEASGVELRIHEGPVLTAHTQRLLHTTSFAIKRPSLASRSSGRSSLSSAQSMYNINELSTRFTSDADLIFDSGRKAAALLDEVQPQLRSSVKPGHSRANGSVVSADSAASSEDIYYDLYAAQYKLPRVNQRQHSCEEDSSAI
Protein: Kinesin-like calmodulin binding protein (Kinesin-like calmodulin-binding protein isoform X2) (Q7Y1U0)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAVPAELAGAIPLIDRFQVEAFLRMMQKQINSSGKRSFFSKKSVGTQVREKFTFEDMLCFQKDPIPTSLLKINSDLVSRATKMFHMILKYMGVDSSERVTSVGFDERVELVLKLYKQTLKRAELRDELFVQISKQTRNNPDRQNLIKAWELMYLCASSMPPSKDIGGYLSEYVHNVAHSANDSEVQTLALNTLNALKRSVKAGPRNTIPGREEIEAILTNRKLTTIVFFLDETFEEITYDMTTTVSDAVEELANIIKLSAYSSFSLFECRKVVNGSKSADLGNEEYIGLDDNKYIGDLLAEIKAAKERSKGEILQCKLIFKKKLFRESDEAVTDPMFVQLSYFQLQHDYILGNYPVGRDDAVQLSALQILAEIGFVCSPESCTDWNTLLERFLPRQIALTRARREWELDILSRYRSMEHLTKDDARQQFLRILRTLPYGSSIFFSVRKIDDPIGLLPGRIVLGINKRGVHFFRPVPKEYLHSAELRDIMQFGSSNTAVFFKMRVAGVLHIFQFETKQGEEICVALQTHINDVMLRRYSKARSVANGSVNGDVSNNFKPPSLEVYEKRVQDLSKAVEESQKNTNQLLGELHEKQKQELKTQEELECLKNALRKEKEDLMEVMLDRDRIRSLCEEKDTALQAALLEKKTVEVRLAKLGNLALENNAKGNMAVTVNEPLHKLQDKLKLRNEELHMAVEKTKRLTNEKVILEQRITELERKKDEEVKILKKSYEQECRSLKFQMSELGMKLERVTNELAVSESTLAVRNADFSALQNNLKELEELREMREDIDRKNEQTAAILKMQGAQLAELEVLYKEEQILRKRYFNTIEDMKGKVRVFCRLRPLNEKEMLEKERKVLMGLDEFTVEHPWKDDKAKQHMYDRVFDDSATQEDIFEDTRYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGSDNNPGLTPRAIAELFKILRRDSNKFSFSLKAYMVELYQDTLVDLLLPKNAKRLKLDIKKDSKGMVAVENATVIPISTFEELKSIIQRGSERRHISGTQMNEESSRSHLILSVVIESTNLQTQSVARGKLSFVDLAGSERVKKSGSVGDQLKEAQSINKSLSALGDVISALSSGSQHIPYRNHKLTMLMSDSLGGNAKTLMFVNVSPAESNLDETYNSLTYASRVRSIVNDASKNISSKEVVRLKKLVAYWKEQAGRRGDEEDYEDIQEEQTRKDRTDGRHSM
Protein: Thrombospondin-4 (Q9Z1T2)
Organism: Mus musculus (Mouse)
Function: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:22682248}. Sarcoplasmic reticulum {ECO:0000269|PubMed:22682248}. Secreted {ECO:0000269|PubMed:22682248}. Secreted, extracellular space {ECO:0000269|PubMed:22682248}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:22362893, ECO:0000269|PubMed:22682248}.
Interaction partners:
- Leukocyte surface antigen CD47
- Platelet glycoprotein 4
- Integrin beta-3
- Integrin beta-1
- Syndecan-4
- Cyclic AMP-dependent transcription factor ATF-6 alpha
- Syndecan-1
- Integrin alpha-3
- Integrin alpha-V
- Integrin alpha-IIb
Sequence:
MPAPRAAAAAFLLLHLVLQPWQRTSAQATPQVFDLLPSSSQRLNPSALQPVLTDPTLHEVYLISTFKLQSKSSATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLSNLQRGDGSVELYLDCAQADSVRNLPRAFSGLTQNPESIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPIAPPAPPTRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKYHPCYPGVRCVNLAPGFRCDACPVGFTGPMVQGVGINFAKTNKQVCTDVDECQNGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKTERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGDGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDKDIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQSFDRLDN
Protein: Adipokinetic hormone (Hypertrehalosaemic hormone) (HRTH) (dAKH) (P61855)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probably causes a marked increase in hemolymph carbohydrate.
Subcellular location: Secreted.
Interaction partners:
- Adipokinetic hormone receptor, isoform C
- GEO11536p1
- Short neuropeptide F
- Cardioactive peptide
- Corazonin receptor, isoform B
- Insulin-like peptide 2
- Insulin-like peptide 3
- Neuropeptide F
- Allatostatin-A
- Insulin-like peptide 5
Sequence:
MNPKSEVLIAAVLFMLLACVQCQLTFSPDWGKRSVGGAGPGTFFETQQGNCKTSNEMLLEIFRFVQSQAQLFLDCKHRE
Protein: L-type lectin-domain containing receptor kinase V.7 (Arabidopsis thaliana lectin-receptor kinase a3) (AthlecRK-a3) (LecRK-V.7) (EC 2.7.11.1) (Q9ZR79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9LSR8}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Concanavalin A-like lectin family protein
- Concanavalin A-like lectin family protein
- Concanavalin A-like lectin family protein
Sequence:
MSHKVLQIVLVLLLTLFSSTHNSNGNFLMEEAAAAGLNGYCLLTNTTKHSYGQAFNNTPVPIKNSSFSFNIIFGIVPEHKQQGSHGMAFVFSPTRGLPGASPDQYLGIFNETNNGKASNNVIAIELDIRKDEEFGDIDDNHVGININGLTSVASASAGYYDDEDGNFKKLSLISTKVMRLSIVYSHTDKQLNVTLLPAEISVPPQKSLLSLNRDLSPYFLEETYLGFTASTGSIGALYYVMQFSYEEGVIYPAWDLGVIPTLPPYPKKSYDRTRRILAVCLTLAVFTALVASGIGFVFYVRHKKVKEVLEEWEIQNGPHRFSYKELFNATKGFKEKQLLGKGGFGQVYKGMLPGSDAEIAVKRTSHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCKHKENLYLVYDFMPNGSLDRCLTRSNTNENQERLTWEQRFKIIKDVATALLHLHQEWVQVIVHRDIKPANVLLDHGMNARLGDFGLAKLYDQGFDPQTSRVAGTLGYIAPELLRTGRATTSTDVYAFGLVMLEVVCGRRLIERRAAENEAVLVDWILELWESGKLFDAAEESIRQEQNRGEIELVLKLGLLCAHHTELIRPNMSAVLQILNGVSHLPNNLLDVVRAERLRGIPETSMEVLLGLDLNSFGTMTLTNSFVSHGR
Protein: DKFZP586N0721 protein (HCG23972) (cDNA, FLJ94430) (Q6I9W9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MACTYVSNLGKKQRSVSFLASGLMRVSTGPELRLHHSFVLTGDVGRRICRLLVGLFTKGDTSSKRVHPFSPGPCFLLCDLARVGSSPKINVSPFYQNQTSTQRSCTVFVWQRCSLVGPFQVTVFTMYFHHSLRSISRFSSG
Protein: Cytoskeleton-associated protein 2-like (Radial fiber and mitotic spindle protein) (Radmis) (Q8IYA6)
Organism: Homo sapiens (Human)
Function: Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells.
Subcellular location: Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:25439729}. Note=Uniformly distributed along each microtubule bundle of spindles in addition to centrioles during mitosis, expression promptly diminishes at interphase. {ECO:0000269|PubMed:25439729}.
Interaction partners:
- Holliday junction recognition protein
- Maternal embryonic leucine zipper kinase
- Disks large-associated protein 5
- Centrosomal protein of 55 kDa
- Abnormal spindle-like microcephaly-associated protein
- Cell division cycle-associated protein 2
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Condensin complex subunit 3
- Kinesin-like protein KIF14
- Sororin
Sequence:
MVGPGPTAAAAVEERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKSTIRPKNDVTNHVVLPVKPKRSISIKLQPRPPNTAGSQKPKLEPPKLLGKRLTSECVSSNPYSKPSSKSFQQCEAGSSTTGELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENESLDNFLKETNKENLLDILTEPERKPDPKLYTRSKPKTDSYNQTKNSLVPKQALGKSSVNSAVLKDRVNKQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNIKDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKMESVKSCLSPKEREQVTATPRIAKAEQHNYPGIKLQIGPIPRINGMPEVQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVVASLDELLEVEETKCFIFRRNEALPVTLGFQTPES
Protein: Pre-mRNA-processing factor 39 (O74970)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Function prior to stable branch point recognition by the U1 snRNP particle to facilitate or stabilize the U1 snRNP/5'-splice site interaction. Has a direct role in the assembly or function of a catalytically active spliceosome (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- U1 small nuclear ribonucleoprotein 70 kDa homolog
- U1 small nuclear ribonucleoprotein C
- U1 snRNP-associated protein usp107
- U2 small nuclear ribonucleoprotein A'
- U1 snRNP-associated protein usp106
- Small nuclear ribonucleoprotein-associated protein B
- Pre-mRNA-processing protein prp40
- Small nuclear ribonucleoprotein Sm D1
- Pre-mRNA-splicing factor cdc5
- Nuclear cap-binding protein subunit 2
Sequence:
MDYGDIYIAEETEWDKYNRQINKNPDDFDAWEGLVRASEHLEGGVGRNSSKQAINTLRSVYDRFLGKYPLLFGYWKKYADFEFFVAGAEASEHIYERGIAGIPHSVDLWTNYCAFKMETNGDANEVRELFMQGANMVGLDFLSHPFWDKYLEFEERQERPDNVFQLLERLIHIPLHQYARYFERFVQVSQSQPIQQLLPPDVLASIRADVTREPAKVVSAGSKQITVERGELEIEREMRARIYNIHLQIFQKVQLETAKRWTFESEIKRPYFHVKELDEAQLVNWRKYLDFEEVEGDFQRICHLYERCLITCALYDEFWFRYARWMSAQPDHLNDVSIIYERASCIFASISRPGIRVQYALFEESQGNIASAKAIYQSILTQLPGNLEAVLGWVGLERRNAPNYDLTNAHAVLRSIINEGKCNTGITEVLITEDIKLVWKIEGDIELARNMFLQNAPALLDCRHFWISFLRFELEQPLNSKNYTEHHARVSNVMEMIRNKTRLPPRTIMDLTKLYMEYLCHQSNDPSVLQEYLLIDRDVFGPFSVRESHWKKLDEGQDLKQVSTRLLSTNGHPGISVNEAKIKSGESPYEKYYRLQGVVETVTSGVAANGSS
Protein: Suppressor protein SRP40 (P32583)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known; weak suppressor of a mutant of the subunit AC40 of DNA dependent RNA polymerase I and III.
Interaction partners:
- Nucleolar protein 56
- Nucleolar protein 58
- H/ACA ribonucleoprotein complex subunit CBF5
- rRNA 2'-O-methyltransferase fibrillarin
- C-1-tetrahydrofolate synthase, cytoplasmic
- Serine hydroxymethyltransferase, mitochondrial
- Serine hydroxymethyltransferase, cytosolic
- Proteasome-interacting protein CIC1
- 25S rRNA
- Ribosome biogenesis protein MAK21
Sequence:
MASKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAWELTDNTYKGAAGTWGEKANEKLGRVRGKDFTKNKNKMKRGSYRGGSITLESGSYKFQD
Protein: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase (EC 5.3.3.21) (Peroxisomal di-isomerase DCI1) (Q08558)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Peroxisomal di-isomerase that is involved in fatty acid metabolism enzyme by converting 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl-CoAs. Required for ECI1 to be locazed to the peroxisome.
Subcellular location: Peroxisome {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:10455114, ECO:0000269|PubMed:10639339}.
Interaction partners:
- 3,2-trans-enoyl-CoA isomerase
- 3-ketoacyl-CoA thiolase, peroxisomal
- Acetyl-CoA acetyltransferase
- Peroxisomal hydratase-dehydrogenase-epimerase
- Acyl-coenzyme A oxidase
- Peroxisomal acyl-coenzyme A thioester hydrolase 1
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein bL36m
Sequence:
MSSRVCYHINGPFFIIKLIDPKHLNSLTFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFSSGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAIGLSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELIGTIITKNYQLTNTETFNEKVLQDIKQNLEGLYPKSVLGMKELLHSEMKQKLIKAQAMETNGTLPFWASGEPFKRFKQLQEGNRRHKL
Protein: Arachidonate 5-lipoxygenase a (Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.34)) (B8A697)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Leukotriene A
- Cytochrome P450, family 4, subfamily F, polypeptide 3
- Prostaglandin-endoperoxide synthase 1.
- Prostaglandin-endoperoxide synthase 2a.
- Glutathione peroxidase
- Glutathione peroxidase
- Arachidonate 12-lipoxygenase
- Leukotriene C4 synthase
- Glutathione peroxidase
- Probable glutathione peroxidase 8
Sequence:
MPSYTVTVATGTQWFAGTDDYIYLTLVGSEGCSDRTLLDKPLYNDFERGAVDSYDISVGEDLGEIQLVKIEKKKYWMHDDWYCKYITVKTPYGDYVEFPCFRWLVDDKEVILRDGRARLPQHDKTGVAKQHRRKELEQRQKTYRWKEWHPGFPMSIDCKAHKELPRDIQFDSEKGVDFVLNYSKAIENLYVNQFMHMFQSSWGDFADFERIFVRIKNTISEYVMEHWKEDFMFGYQYLNGCNPVVIKKCTEIPDKFPVTHNIVEDSLERGLTLEEELKEGNIFIADYEIMDGVTANSTDPCTLQYLAAPMCLLYKNSQNKIMPIAIQLHQKPGEDNPIFLPSDDEYDWLLAKIWVRSSDFHVHQTVTHLLRTHLISEVFGIAMFRQLPAVHPVFKLLLPHIRFTIAINTKAREQLICECGLFDKANGTGGGGHIELVQRSMKVFTYKSLCFPENIKARGMDSQEELPYYFYRDDGCAVWETVKSFVSDVVDIYYDKDETVQEDEEIQAFVKDVCSFGMQDLDHCEFPKSLQTKEELVEYLTVVIFTASAQHAAVNFGQYDWCSWIPNSPPTMRKPPPMKKGEVDLQYIVESLPDRGRSCWHLGAVWALSQFQENELFLGMYPDEHFIEKPVKEVMVKFGKKLAEVSKTIKNRNEGKKLPYYYLSPDRIPNSVAV
Protein: T. brucei spp.-specific protein (Q38A68)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSTTLVETLQEEIGALQAEVARLRIMVHRVTRGTDAVICPATKGDIPHRIPHENGSASEKSMGHADVVSQDLVLLLKRLLQSPGICLGQSSDTAPVCTDATAEPDGSTKKKPKRKRREKGERKQEEAENKSRPREVTERSSGLSPTKKQPVECAIPSDPKKTPVREQAGEKEERAVLPATRNVSTPRRASASEEPRLAPAATTGSKQSNEDNVVQQQTVRKRSVPPPSPGSLVSIPRDGFLSYEHHDEEPTHQPPLVGVTQRVGRRALSSSSSSDDLPVGTGWVPTASVLDEETPQMEEVSRATRSISSVGRLAERSRPSPVRDTNLTDIDDTHLSIKSHRGIVECVHESNDGLDGARGRMQFVSVDFSRSQQVKRRKLLSRLRDSSFDSEETCEEDLMAEHPSPTQRSTTLNAQQTIKPPQIPNEVERAGSTSTRSEVAMSHRSYTHAQSAGYVLDMLSDCEFTEDVAA
Protein: Pre-mRNA-processing ATP-dependent RNA helicase prp11 (EC 3.6.4.13) (Q9P7C7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: ATP-dependent RNA helicase involved in pre-spliceosome/complex A assembly and mRNA splicing. Bridges U1 and U2 snRNPs during pre-spliceosome assembly and enables stable U2 snRNP association with intron RNA. Through its helicase activity probably catalyzes an ATP-dependent conformational change of U2 snRNP.
Subcellular location: Nucleus {ECO:0000305|PubMed:14713954}.
Interaction partners:
- Pre-mRNA-splicing factor dre4
- Branchpoint-bridging protein
- U2 snRNP component prp10
- Pre-mRNA-splicing factor sap114
- Pre-mRNA-splicing factor sap61
- Pre-mRNA-splicing factor sap62
- Pre-mRNA-splicing factor prp12
- Uncharacterized protein C1782.03
- Small nuclear ribonucleoprotein Sm D1
- Spliceosome-associated protein 49
Sequence:
MSRRTRSRSPPRRSYNRERRDYRKYDDSEDQKGARYNRYVDDVSSRRDRHDSFRSHESNKIRRDNSWKHDKYSYEKRYQERDREYARSKNIPDQYIGRSPRPTSHRHAEEKEVDNKTKSDETNPVLQGSATEIKPQPRRSRFDRTERVGASLSVSEIQSENPRVDVIPKDKAVENNHQRNAEKPVASDKITDAKLLARLERVRAWKESKAKQEASKKEEHKLNTKPQVTAKDQNAMPSTGISGFEINRQKDTSDMKRNNRVHMDDEDGPRRMNLEDYQELWDQEDRGMLGNEQAASMEEDEVDPLDAYMASLVGTTDTIRPGLLNTEVIDPNANDDERMVISETLEEEENLLALAAKRSKKKDVITVDHSKINYEDFKKDFYVEPEELKNLSPAEVDELRASLDGIKIRGIDCPKPVTSWSQCGLSAQTISVINSLGYEKPTSIQAQAIPAITSGRDVIGVAKTGSGKTIAFLLPMFRHIKDQRPLKTGEGPIAIIMTPTRELAVQIFRECKPFLKLLNIRACCAYGGAPIKDQIADLKRGAEIVVCTPGRMIDVLSANAGRVTNLHRCTYLVLDEADRMFDLGFEPQVMRIINNIRPDRQTVLFSATFPRAMEALARKVLKKPVEITVGGRSVVASEVEQIVEVRPEESKFSRLLELLGELYNNQLDVRTLVFVDRQESADALLSDLMKRGYTSNSIHGGKDQHDRDSTISDYKAGVFDVLIATSVVARGLDVKSLQLVVNYDCPNHMEDYVHRVGRTGRAGHTGVAVTFITPEQEKYAVDIAKALKMSKQPVPKELQTLASQFLEKVKAGKEKAAGGGFGGKGLSRLDETRNAERKMQRKAYGEDEEDVETEAEAKSPLEKITPEKSTGDPTLDRVRAAVGGIAARAFANQTAQSNKLTQPISIIKTDGDEYKAKMEINDYPQQARWAVTNNTNIVHVTELTGTSITTKGNFYLPGKNPEPGEEKLYLWIEGPSELVVNRAITELRRLLLEGINHSLEGGNKPSASGRYTVV
Protein: Cellulose synthase A catalytic subunit 4 [UDP-forming] (AtCesA4) (EC 2.4.1.12) (Protein IRREGULAR XYLEM 5) (AtIRX5) (Q84JA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the secondary cell wall formation. Required for the xylem cell wall thickening.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cellulose synthase A catalytic subunit 7
- Cellulose synthase A catalytic subunit 8
- COBRA-like protein 4
- Probable galacturonosyltransferase 12
- Beta-1,4-xylosyltransferase IRX9
- Transcription factor MYB46
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 1
- Laccase-17
- Probable glucuronoxylan glucuronosyltransferase IRX7
- Chitinase-like protein 2
Sequence:
MEPNTMASFDDEHRHSSFSAKICKVCGDEVKDDDNGQTFVACHVCVYPVCKPCYEYERSNGNKCCPQCNTLYKRHKGSPKIAGDEENNGPDDSDDELNIKYRQDGSSIHQNFAYGSENGDYNSKQQWRPNGRAFSSTGSVLGKDFEAERDGYTDAEWKERVDKWKARQEKRGLVTKGEQTNEDKEDDEEEYLDAEARQPLWRKVPISSSKISPYRIVIVLRLVILVFFFRFRILTPAKDAYPLWLISVICEIWFALSWILDQFPKWFPINRETYLDRLSMRFERDGEKNKLAPVDVFVSTVDPLKEPPIITANTILSILAVDYPVNKVSCYVSDDGASMLLFDTLSETSEFARRWVPFCKKYNVEPRAPEFYFSEKIDYLKDKVQTTFVKDRRAMKREYEEFKVRINALVAKAQKKPEEGWVMQDGTPWPGNNTRDHPGMIQVYLGKEGAFDIDGNELPRLVYVSREKRPGYAHHKKAGAMNAMVRVSAVLTNAPFMLNLDCDHYINNSKAIRESMCFLMDPQLGKKLCYVQFPQRFDGIDLNDRYANRNIVFFDINMRGLDGIQGPVYVGTGCVFNRPALYGYEPPVSEKRKKMTCDCWPSWICCCCGGGNRNHKSDSSKKKSGIKSLFSKLKKKTKKKSDDKTMSSYSRKRSSTEAIFDLEDIEEGLEGYDELEKSSLMSQKNFEKRFGMSPVFIASTLMENGGLPEATNTSSLIKEAIHVISCGYEEKTEWGKEIGWIYGSVTEDILTGFRMHCRGWKSVYCMPKRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYAWGGKLKILERLAYINTIVYPFTSIPLLAYCTIPAVCLLTGKFIIPTINNFASIWFLALFLSIIATAILELRWSGVSINDLWRNEQFWVIGGVSAHLFAVFQGLLKVLFGVDTNFTVTSKGASDEADEFGDLYLFKWTTLLIPPTTLIILNMVGVVAGVSDAINNGYGSWGPLFGKLFFAFWVIVHLYPFLKGLMGRQNRTPTIVVLWSILLASIFSLVWVRIDPFLPKQTGPLLKQCGVDC
Protein: adenylate cyclase (EC 4.6.1.1) (D1MIA3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MDETPFQKVKTRRRRSHCPPGTIACEDEFDCAELEALFRRYRLKLEQTATLKALSVLILLSCSLSLLELLLSGTGLSVAQGSHPVHSVLFISLFIVTNVQYLLVTQLQQIAHLSLLFGFTFAVPCCPLPQVSRAAGPEQGVWPLLLLTFMAYCLLPVRTGLALLFGLLLPLAHTLITASTLPDNTQRLWRSLVANTLLFTGVNVSGLFVRILTERAQRKAFLQARNCIEERLRMEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGSTSLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPGKVHITRSTLECLNGDYEVEPGNGRERHAFLLKHDIETFFIVPPHRRKIFPGLILSDIKPAKKMKFKTVCYLLVQLMHCRKMFRAEIPFSNVMNCEDGDKRRVLRSAPEKLRNRTPTAASAPQSSPGTRVNRYINRLIEARQTESDTADLNYLTLMYRDSERERRYHQLNDEYFTGAVVLSLLLVVLLGFLYLLIIPQGTVVLVLLVFCICFLVVCIMYLHITRVQCFPGCLTIQIRTALCVFIVLLIYAVAQACVVGCMPWLWPSNSTRSIVIIDAAAGLNRTMAELPCAGAQYAFLCCMLGTLSMALFLRVSWIPKTILLLLLLVLYITILELSGFRRASGWALLSVRGLEPLLSLLLFSTAVALHSRQLDLKLRLDFLWATQAEEERDGMEKVKLDNKRILFNLLPVHVAQHFLLSNPRNMDLYYQSYAQVGVLFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKECYKDIEKIKTIGSTYMSAVGLVPTIGTKAKKSTATHLSTIADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPGKIQVTEDVYRLLQNNYDLMCRGNVSVKGKGQMLTYFLEGKAQDPGIRAPHHTGGLERRVHAIARTSSTQTKAGSVSSATSGLAVRVGLSSSFHGPHGHSNTTNVPTVGEEEETKEQEV