wanglab/gogpt-training-data huggingface dataset:
Protein: Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Q8IVH8)
Organism: Homo sapiens (Human)
Function: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase 1
- Drebrin-like protein
- Drebrin
- Endophilin-A2
- Growth factor receptor-bound protein 2
Sequence:
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSRNVREEKTRSEITFGQVKFDPPLRKETEPHHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQRGHVAHLEDDEGDDDESKHSTLKAKIPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPPPRLPPHKPVALGNGMSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY
Protein: Ribosomal protein L11, putative (Q586R9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 50S ribosomal protein L17, putative
- Large ribosomal subunit protein uL15/eL18 domain-containing protein
- Large ribosomal subunit protein bL21m
- 30S Ribosomal protein S17, putative
- Large ribosomal subunit protein uL3m
- 50S ribosomal protein L13, putative
- 50S ribosomal protein L2, putative
- KOW domain-containing protein
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL43
Sequence:
MLRACGVLQLRARPKTVCVEPGSNRLPEALVVEKARDIFGRPEFPGKRVLHNWRFFIKAGKAATGPPVGQEFSKLGLKAMDFAKVFNDRTKPHFKEDVELIVRIQVYFDKSYLFTIEPPPTAWFILRALRKKRRETGPVPLRGHYCALMTLEMAYEIAKMKPLCWGRPEYPLLETRVRRVVGQARRMGVCFIGVDTPYSSPVKDMTEQQYTEECERYRRIHMEQYTTLRQRELEEAPLIERLHRPNMSPLTDEQIEEGLRDPCLLDTLWRASHPLSPYHRDLRERELARRYLNARGWVKDMTPEEMRIVFMNYRLPEGEKRKQMDEAAMSGEVYWTRDGAQL
Protein: Calcium-binding protein 2 (CaBP2) (Q9JLK4)
Organism: Mus musculus (Mouse)
Function: Required for sound encoding at inner hair cells (IHCs) synapses, likely via inhibition of the inactivation of voltage-gated calcium channel of type 1.3 (Cav1.3) in the IHCs. Required for the normal transfer of light signals through the retina.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus {ECO:0000250}.
Interaction partners:
Sequence:
MGNCAKTPWHRGSKERWQWPGSPLGGSRPSPGPRTEEQEGTQGYSVLGSLVGPACIFLRPSIAATQLDRELRPEEIEELQIAFQEFDRDRDGYIGYRELGACMRTLGYMPTEMELIEISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGCISVGELRAALKALLGERLSQREVDEILQDIDLNGDGLVDFEEFVRMMSR
Protein: RING-box protein 1a (At-Rbx1;1) (Protein RING of cullins 1) (RBX1-2) (RBX1a-At) (Q940X7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The SCF complex plays a crucial role in regulating response to auxin and is essential for growth and development. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL1.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Cullin-3A
- Cullin-2
- Putative cullin-like protein 2
- Putative cullin-like protein 1
- Cullin-like protein 3
- Cullin-4
- SKP1-like protein 1A
- Cullin-1
- Elongin-C
- Cullin-3B
Sequence:
MATLDSDVTMIPAGEASSSVAASSSNKKAKRFEIKKWSAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNSEWEFQKYGH
Protein: Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib) (Q8TF66)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000269|PubMed:36228039, ECO:0000269|PubMed:36735681, ECO:0000269|PubMed:36757924}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MPLKHYLLLLVGCQAWGAGLAYHGCPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVRGQSLIIINVNVAVPSVHVPEVPSYPETPWYPDTPSYPDTTSVSSTTELTSPVEDYTDLTTIQVTDDRSVWGMTQAQSGLAIAAIVIGIVALACSLAACVGCCCCKKRSQAVLMQMKAPNEC
Protein: RNA helicase (EC 3.6.4.13) (O18056)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MADWGIAFDEQCRSEGLEVPEKTEKVQSGSEMDQNEENKGSNGWGISRGGMFGGPKASNAPPPQTSFGSTSGTRVGGSFGGQAGVDGRGAPLGSAEELIGGVPIMPGQSQPMRGGFQGAYRGGRGSGGGQMDFGAPGQGQSMGRGRGQQNPAFVPRPRDTPPQYGGHQAAQQFVKPDSKYKFTKPATEEAHEQVPVPADIALLNKFIQKEVKMMKDVVVDVQRQDPKSPLYSISSFRELRLKPEVLKALDTMNFQFPTRIQETALPLLLMEPPSNLIAQAQSGTGKTAAFVLTMLCRIDVNLMCPQCICLAPTLELAKQIGEVVEKMGKFIDNLKIHYAIKGGNMAAMRGRKLTEQIVIGTPGITRDYLQKYKCIDPSKIRCLVLDEADVMIYHQGFTDISTTIYNMVEDASDSVQSMLFSATYDEPVINFATKIIKNAIVVMLKREEQALPNIKQFYVQCACRDSKYAAIVNLYSGLAVASSVIFCHTKASVMWLYENMRARGHQVDVLHGDMTVVERADTIIHFKRGDFKVLITTNVFARGIDVAQVSVVINYDLPIKYTDEGTPMVVDGFTQPDCETYLHRIGRTGRFGKTGIAINLIDSEDSMNMINVLENHFQMKIARMDPSNLVELEAIEMA
Protein: Cytochrome P450 family protein (Cytochrome P450, family 705, subfamily A, polypeptide 23) (Cytochrome P450-like protein) (Q9LJY4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MAAMLTVEFQNCLIFILLCILLLLCYPLFFKKPKVSQDGFGLPPSPLSLPIIGHLHLLFSNLTHKSLQKLSSKYGPLLYLRIFNVPIIFVSSASVAYEIFRGHDVNISFRGNPPIEESLLVGSFGFFTAPYGDYWKFMKKVMVTKLLGPQALQRSRGIRADALERFYMNLLDKAMKKESVEIGKETMKLIYDSICKMIMGRNFSEENGEAERVRGLVTESTALTKKIFMANVLHKPLKKLGISLFKKEIMDVSNSFDELLERFLVEHEEKLNEDQDMDMMGVLLAACRDKNAECKITRNHIKSLFVDLVVAGTDTSRHATQWTMAEIINKPKVLEKVREEIYSVVGRTRLVQETDLPSLPYLQATVKEGLRLHPPGPLFARTAREGFSVGGFYVPENTPLVVNAYAMMRDPGSWEDPNEFKPERFLGSGKEDEREHGLKYIPFGSGRRGCPGINLAYILVGTAIGVMVQCFDWKIKGNKVNMEEARGSLVLTMAHPLKCIPVARTQIPSC
Protein: Hypoxia-inducible factor 1 (Hypoxia-induced factor 1) (G5EGD2)
Organism: Caenorhabditis elegans
Function: A transcription factor which is a key regulator in various cellular processes; including environment stress resistance (oxygen levels, hydrogen sulfide and cyanide levels and heat), negative regulation of cell apoptosis in ASJ neurons by inhibition of cep-1 via transcriptional activation of tyr-2, resistance/susceptibility to pathogenic bacteria, lifespan and brood size. Involved in mediating susceptibility to enteropathogenic E.coli. Increased levels of hif-1 activity confer resistance to P.aeruginosa-mediated death but also confer susceptibility to S.aureus infection. Required for aha-1 nuclear localization. Following hypoxic stress, up-regulates serotonin levels through activation of tph-1 expression. Role in life span extension is dependent of temperature. Not required for survival in anoxic conditions. Involved in iron homeostasis by repressing transcription of ferritin ftn-1 and ftn-2, and divalent metal transporter smf-3. May be involved in manganese homeostasis by repressing divalent metal transporter smf-3.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:19889840}.
Interaction partners:
- Aryl hydrocarbon receptor nuclear translocator homolog
- von Hippel-Lindau tumor suppressor homolog
- Hypoxia-inducible factor prolyl hydroxylase
- Forkhead box protein O
- RNA polymerase II transcription factor SIII p18 subunit
- ubiquitinyl hydrolase 1
- Cullin-2
- Heat shock protein 90
- Protein skinhead-1
- Elongin-C
Sequence:
MEDNRKRNMERRRETSRHAARDRRSKESDIFDDLKMCVPIVEEGTVTHLDRIALLRVAATICRLRKTAGNVLENNLDNEITNEVWTEDTIAECLDGFVMIVDSDSSILYVTESVAMYLGLTQTDLTGRALRDFLHPSDYDEFDKQSKMLHKPRGEDTDTTGINMVLRMKTVISPRGRCLNLKSALYKSVSFLVHSKVSTGGHVSFMQGITIPAGQGTTNANASAMTKYTESPMGAFTTRHTCDMRITFVSDKFNYILKSELKTLMGTSFYELVHPADMMIVSKSMKELFAKGHIRTPYYRLIAANDTLAWIQTEATTITHTTKGQKGQYVICVHYVLGIQGAEESLVVCTDSMPAGMQVDIKKEVDDTRDYIGRQPEIVECVDFTPLIEPEDPFDTVIEPVVGGEEPVKQADMGARKNSYDDVLQWLFRDQPSSPPPARYRSADRFRTTEPSNFGSALASPDFMDSSSRTSRPKTSYGRRAQSQGSRTTGSSSTSASATLPHSANYSPLAEGISQCGLNSPPSIKSGQVVYGDARSMGRSCDPSDSSRRFSALSPSDTLNVSSTRGINPVIGSNDVFSTMPFADSIAIAERIDSSPTLTSGEPILCDDLQWEEPDLSCLAPFVDTYDMMQMDEGLPPELQALYDLPDFTPAVPQAPAARPVHIDRSPPAKRMHQSGPSDLDFMYTQHYQPFQQDETYWQGQQQQNEQQPSSYSPFPMLS
Protein: Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS) (Q8N0Z2)
Organism: Homo sapiens (Human)
Function: Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
Subcellular location: Cytoplasm, myofibril, sarcomere {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines. {ECO:0000250}.
Interaction partners:
- Actin-binding LIM protein 3
- Actin-binding LIM protein 2
- Actin-binding LIM protein 1
Sequence:
MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK
Protein: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-) (O35459)
Organism: Mus musculus (Mouse)
Function: Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q62651}. Peroxisome {ECO:0000250|UniProtKB:Q62651}.
Interaction partners:
- Enoyl-CoA delta isomerase 1, mitochondrial
- Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
- 3-ketoacyl-CoA thiolase, mitochondrial
- Peroxisomal targeting signal 1 receptor
- Trifunctional enzyme subunit beta, mitochondrial
- Enoyl-CoA delta isomerase 2
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Carnitine O-palmitoyltransferase 2, mitochondrial
- 2,4-dienoyl-CoA reductase [
- Hydroxysteroid dehydrogenase-like protein 2
Sequence:
MATAMTVSSKLRGLLMQQLRGTSQLYFNISLRSLSSSAQEASKRAPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASELMQPSGDDAARIAWYLRDLISKYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLVSACDIRYCTQDAFFQIKEVDMGLAADVGTLQRLPKVIGNQSLVNELTFSARKMMADEALDSGLVSRVFQDKDAMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKRDTKSITFSKL
Protein: SRA stem-loop-interacting RNA-binding protein, mitochondrial (Q9D8T7)
Organism: Mus musculus (Mouse)
Function: RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters (By similarity). {ECO:0000250}.
Interaction partners:
- Leucine-rich PPR motif-containing protein, mitochondrial
- Mitochondrial import receptor subunit TOM7 homolog
- NADH dehydrogenase 1 subunit C1, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 4
- Poly
- Pseudouridylate synthase 1 homolog
- G-rich sequence factor 1
Sequence:
MAASAIKGLSALRSSTGRPIAFVRKIPWTAAASELREHFAQFGHVRRCTVPFDKETGFHRGMGWVQFSSQEELQNALQQEHHIIDGVKIHVQAQRAKALHGAQTSDEERFLR
Protein: MADS-box transcription factor 1 (OsMADS1) (Protein LEAFY HULL STERILE 1) (Protein SEPALLATA-like) (Q10PZ9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor involved in the development of floral organs. Required for the formation of inner floral organs (lodicules, stamens and carpels, or whorls 2, 3 and 4) and the lemma and palea (whorl 1), which are grass floral organs analogous to sepals. May be involved in the control of flowering time. Seems to act as transcriptional activator. May act upstream of the auxin-responsive protein GH3.8.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- MADS-box transcription factor 14
- MADS-box transcription factor 15
- MADS-box transcription factor 6
Sequence:
MGRGKVELKRIENKISRQVTFAKRRNGLLKKAYELSLLCDAEVALIIFSGRGRLFEFSSSSCMYKTLERYRSCNYNSQDAAAPENEINYQEYLKLKTRVEFLQTTQRNILGEDLGPLSMKELEQLENQIEVSLKQIRSRKNQALLDQLFDLKSKEQQLQDLNKDLRKKLQETSAENVLHMSWQDGGGHSGSSTVLADQPHHHQGLLHPHPDQGDHSLQIGYHHPHAHHHQAYMDHLSNEAADMVAHHPNEHIPSGWI
Protein: Gliotactin (Q9NK80)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMHKLKYRDKLKWLLALLVLIGTCFIQTRGQTRDPRFYSRPGVDYHWPNPGDPDYRTYTFNDRRYGHYQPNGYGANYPGRNPPGQYPQGMPNEDRFRFDPNDPNARTQFPGVLAGWREDLQGKQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTKTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYMYTFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVIGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVACFFLIVLVVICCIMWRNAKRQSDRFYDEDVFINGEGLEPEQDTRGVDNAHMVTNHHALRSRDNIYEYRDSPSTKTLASKAHTDTTSLRSPSSLAMTQKSSSQASLKSGISLKETNGHLVKQSERAATPRSQQNGSIAKVASPPVEEKRLLQPLSSTPVTQLQAEPAKRVPTAASVSGSSRSTTPVPSARSTTTHTTTATLSSQPAAQPRRTHLVEGVPQTSV
Protein: NADH-cytochrome b5 reductase, putative (EC 1.6.2.2) (Q387C1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cytochrome b5, putative
- Cytochrome b5, putative
- Dihydroorotate dehydrogenase
Sequence:
MRFVPPFLAGAALATYYRPLDKSKSAYCYASIENALHFQPKPKPGKVFSQRYQPYTLGDVVPITHDTALFRFLIDGNEEFNLKPCSTLQACYKYGVQPMDQCQRFYTPVTANHTKGYFDIIVKRKQGGLMTEHLFGMHIGDKLLFRSVTFKLQYRPNRWKHVGMIAGGTGFTPMLQIIRHSLQEEWDNGMVDRTKLSFLFCNRTERHILLKGLFDDLAQKYSNRFKVYYTIDQAVEPDVWPHYTGLVTKEMVHETMPAPNEEKKIILLCGPDQLLNHVAGTPMGTMNTMSSGMNIQPMAPDLNNLVNLGGILGELGYSNDEVYRF
Protein: [acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39) (Q38DK4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Acyl carrier protein
- Phosphotyrosine protein phosphatase I domain-containing protein
- DNA photolyase, putative
- Rhodanese domain-containing protein
- 30S Ribosomal protein S17, putative
- Superoxide dismutase, putative
- Translation initiation factor IF-2
- Uncharacterized protein
- PROP1-like PPR domain-containing protein
- Dehydrogenase-like protein
Sequence:
MSKSLQRALVFSGQGAHRRGMATEYLRIPAVACLWERMKGSMEQKYGISLQDIITENPTRLYVYNDAYDVAAICERSCQDGGSVVESTPRQKLISHPQGVLSLTSLTQPCMLAAHMVSLEYLKETRGYSVESSEVIAGHSLGEFSALCALGLLSPEVAVDLVYRRGALMEDAVKHSSQSNEGHLMFACNPQRAKLCVEDPDLAVDQLHIFVELIARNLSTTASFIEVVNYNISYEQYVVVGDPIALSALGKCLDPQFRATSCGSSATLDNIVRTAVSSVLQDKQEGITMNPNTGPAPDFVTSCARKYGIRSTFRRFLRGPDDGYTPSLEELTHLTLQEDGRSGLKKKSWFIPLPLSIPFHSSRLRRAMDLFLPVVRDALPDEETMRSFFCIPQCGGSDEGPSSRCASEPKKPVWLTNLTGTAFRPFDVDFQRDALDAMQSMNVGEIRHNGRYHTNLVELAFKNGMDTSSVRDMCAAVLAAQLAHPVQWIDVMDSAVFQHGVREAHEISPVRTVADMFKRTVFRGRTSDASVGEAALDIVTRCLPSEERFL
Protein: Respiratory supercomplex factor 2 homolog C1565.01 (Q9P3B2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255|PROSITE-ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00836}.
Interaction partners:
- Cytochrome c oxidase subunit 13, mitochondrial
- Cytochrome c oxidase subunit 12, mitochondrial
- Cytochrome b-c1 complex subunit 8
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 4, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- HIG1 domain-containing protein C25B8.07c
- Cytochrome c oxidase subunit 6B-like protein new16
- Probable mitochondrial-processing peptidase subunit beta
- Cytochrome c oxidase subunit 3
Sequence:
MKLSTPEEVKAFNRNTYSALFKGALVGSSLGIAGWLIGNRYSAGFRRLPFSLKSWLVIGSGSGASIIFADKAGLKFEAERYGKFDQIDYSTKGLPWNQRALYYFNEHKWPIILGTWASTMGLSLYAASRNRYDTAPQKLIQARMYAQGVTVVVLLGSVYLSTLANRLEPLEREVLVTDPSNPTKLVAFKQRKERYPGELQWEVLVSQDEERLRKLNLPLREPHGSTGPMSTPTPALNSSRSA
Protein: Hyaluronan/mRNA-binding protein domain-containing protein (H2KYR1)
Organism: Caenorhabditis elegans
Interaction partners:
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Ubiquitin-like domain-containing protein
- Large ribosomal subunit protein uL18
- Staphylococcal nuclease domain-containing protein 1
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL15
- Small ribosomal subunit protein uS15
Sequence:
MSTEYGCQVTNKFGLPSDDDDEYDDPRELIQKVSQIAAKKKEEKSVKPAQPVKPAAAPVAATKTDGAAGRGRGGRGRGRGGAGRPRDGERVSNENGDRPQGENRRGGPRRGGERGAARPAGRGGRGGFTRENREGEEPKQEVSFEDGQDTRAPRRRGGFTLGGGPSGGRGGGRGGRGRQFDRQSGSDRTGVRSFDKKDGHGKGNWGDQKDELAGETENIAPEGAESTEPEVPREKTAEELAYEAELAVLAKQKTLKEFKAAAKADAPKFNTRKAGEGAADTFGKLVPIKKEVIPDREEDEVVVIHKAPRKQVLDISITFRNDRPERERNDRSERPQRGGPRGGGRGGGRGGQRQGGHGGRNNTPFNASDDAFPALGAK
Protein: Transcription factor MYB61 (Myb-related protein 61) (AtMYB61) (Q8VZQ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that coordinates a small network of downstream target genes required for several aspects of plant growth and development, such as xylem formation and xylem cell differentiation, and lateral root formation. Regulates a specific set of target genes by binding DNA to the AC cis-element 5'-ACCTAC-3'. Functions as a transcriptional regulator of stomatal closure. Plays a role the regulation of stomatal pore size independently of abscisic acid (ABA). Required for seed coat mucilage deposition during the development of the seed coat epidermis. Involved in the induction of trichome initiation and branching by positively regulating GL1 and GL2. Required for gibberellin (GA) biosynthesis and degradation by positively affecting the expression of the enzymes that convert GA9 into the bioactive GA4, as well as the enzymes involved in the degradation of GA4.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:16005292}.
Interaction partners:
- NAC domain-containing protein 12
- NAC domain-containing protein 73
- Homeobox protein knotted-1-like 7
- NAC domain-containing protein 43
- NAC domain-containing protein 66
- NAC domain-containing protein 10
Sequence:
MGRHSCCYKQKLRKGLWSPEEDEKLLTHITNHGHGCWSSVPKLAGLQRCGKSCRLRWINYLRPDLKRGAFSPEEENLIVELHAVLGNRWSQIASRLPGRTDNEIKNLWNSSIKKKLKQRGIDPNTHKPISEVESFSDKDKPTTSNNKRSGNDHKSPSSSSATNQDFFLERPSDLSDYFGFQKLNFNSNLGLSVTTDSSLCSMIPPQFSPGNMVGSVLQTPVCVKPSISLPPDNNSSSPISGGDHVKLAAPNWEFQTNNNNTSNFFDNGGFSWSIPNSSTSSSQVKPNHNFEEIKWSEYLNTPFFIGSTVQSQTSQPIYIKSETDYLANVSNMTDPWSQNENLGTTETSDVFSKDLQRMAVSFGQSL
Protein: Torsin (E9QHA7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319, ECO:0000256|PIRNR:PIRNR038079}.
Interaction partners:
- Huntingtin.
Sequence:
MNARPPRAWTTLFLCILISGLVVEAIEPVTTSLLVVGTGTAMLGRKIYRYIYENCHENWVNFNATGLKYDLDTKLYGQHVAGQVILKAVTGFMNNKKPKKPLVLSLHGWTGTGKNFVSQLLAENIYVKGMESSFVHLFTATAHFPHEIHIDTYKTQLQDWIRGNVSICPRSMFIFDEMDKMHPGLIDSIKPYLDFYDNLNGVSYREAIFIFLSNAGGENIVQVALDFWKDGKEREEIQLKHLETALSLSVFNNKNSGFWHTSLIDKNLVDFFVPFLPLEYKHIIQCGLAEMIAKGHSPDKEVVEKMAHDLNYFPKEERVFSMQGCKVIPSRLDFYI
Protein: Mothers against decapentaplegic homolog 9 (MAD homolog 9) (Mothers against DPP homolog 9) (SMAD family member 9) (SMAD 9) (Smad9) (Smad8) (Q9JIW5)
Organism: Mus musculus (Mouse)
Function: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.
Subcellular location: Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
Interaction partners:
- Mothers against decapentaplegic homolog 4
- Mothers against decapentaplegic homolog 5
- Mothers against decapentaplegic homolog 1
- Bone morphogenetic protein receptor type-1A
- Activin receptor type-1
- Bone morphogenetic protein receptor type-2
- Bone morphogenetic protein receptor type-1B
- Mothers against decapentaplegic homolog 3
- Mothers against decapentaplegic homolog 7
- Mothers against decapentaplegic homolog 6
Sequence:
MHPSTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQSLCPAPPSSPGHVFPQSPCPTSYPHSPGSPSESDSPYQHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Protein: IQ domain-containing protein C (Q4KMZ1)
Organism: Homo sapiens (Human)
Interaction partners:
- Proline and serine-rich protein 3
- Coiled-coil alpha-helical rod protein 1
Sequence:
MEPELLVRKVSALQACVRGFLVRRQFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDDGRQTFGGTCLLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHIIWDGTLGGPEHSVLDLWRTKPPKGQAPTDRSSRDGTSNEPSHEGQKKQRTIPWRSKSPEILSSTKAGCTGEEQWRGRPWKTEPPG
Protein: Transposase InsE for insertion sequence IS3A (P0CF66)
Organism: Escherichia coli (strain K12)
Function: Involved in the transposition of the insertion sequence IS3.
Interaction partners:
- Transposase InsF for insertion sequence IS3A
- Insertion element IS1 2 protein InsB
Sequence:
MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYESQLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILQKAATYFAKRLK
Protein: RNA-binding Fox protein 1, isoform K (Q9VT98)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MYYPHMVQAGVAPFPGAPAGYAAAPNPGAAVVAAAAAAQQQQQQQQQQQQQQQQAQQQQQQQVAGGPPSAADSLSMAVAAAAAKQSADPVTQMKSGSEAAGSGNSNNNNTAGAGTGAPGAAGGLTTEYSSGGCGGGGASTANSVVVATSVSDVVNASLYMQQKTNLSTQTQTQYEYEYEYNGTSLAEPRVPGPIPHPLTNGHAVDQVQQPPVQQQHLQSSLPPQNVLSISTVLIANEAAESQQSSAMQNAGGGGNTGGGGGGGGGGTPSSPLSNSPSSATASQAGGCGLTLNGSATEGSMSGDTSPVASGEPLLQTPPAHQQQQQQQQPLLCSSPTSMQSSGTSVTGSSIASGTLAATSSSGVGLLPTTGLDSIANGGAPTGCAVVPASTSQVIAHLNAAAAAASGIVSPSANVATSLSSALVPAQSVAAVAAASLDAKSQPKRLHVSNIPFRFRDPDLRAMFGQFGTILDVEIIFNERGSKGFGFVTFANSNDAERARERLHGTVVEGRKIEVNNATARVQTKKVTAVPNVVLTKDGAIPAPALVCVQWPEAAVAAAMRGVAIQRGHVGVVGATPYHHPHHPHHHPALLAASAAAAQQQQQRQLAAAAVATAAVAQQQQQQQQAVVQQQQQQVAAAAQQQHQQQQQQQQQAVQQQQAVQQQQQHQQQQQQQQQQQHAAVAAAAAAASHPHMHAAHAHAHAHALGPQLAQLQAVAVPTAASNAAALQQSLAAAIQNPSGNPNAAAAAAAYAARLSAATGATQSPQTAAAAAAAASMAASANAANNAAALHGFAPVYYDPFLAAAASADPNLRFQAAKPVTEVPAAQPAAILNATAPLLKTPLSQAQQQAYATAATTYTAVAARAAYGAAAAAAAQPALAGYATVAGYAREYADPYLGHGIGPVPGYGATMYRGGFNRFTPY