wanglab/gogpt-training-data huggingface dataset:
Protein: Neurexin-2 (Neurexin II-alpha) (Neurexin-2-alpha) (Q9P2S2)
Organism: Homo sapiens (Human)
Function: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.
Subcellular location: Presynaptic cell membrane {ECO:0000250|UniProtKB:Q9CS84}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Neuroligin-2
- Neuroligin-1
- Neuroligin-3
- Neuroligin-4, Y-linked
- Neuroligin-4, X-linked
- Dystroglycan 1
- Leucine-rich repeat transmembrane neuronal protein 2
- Cerebellin-1
- Disks large homolog 4
- Neurexin-1
Sequence:
MASGSRWRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGVCREGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV
Protein: Uncharacterized protein (Q57ZL7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVVGAVKESSQSLTETFDFGRNSRLLRSETETEPVVFAAPPQTYLYNHKTKGRRTFLQDQTTSSTRLPRILPKGLPYAANFISFEELLGCGTLQTCSQDEVDFSVEDLQLLYQAKCLDQALPPSWERKMRFMELISANCKGKFFCLRESGLGPMSAEAIAHILSSNNKYTILDLSGNRLLDEGACFIAKLISVNRTLVHVGLRSNDIGHIGGEALADALLENNTIISLDVGAHSGINGNHIATEGAKAIGNVLKSNKVLAKLNLGCNGLGHAGISHIASGLDGNESLTHLDISVNNLGYEGAKIIADVLESSCITHLSLQRNNLTDSGGMVIFRAIAAAVENGEDRIEFLNIESNDLSTNSAKAIQKVLTVSSALKQLRISLNCFGSASKFILEGLAENKGLKSLHMASCEIRETDGQPFVTGLSTNATLQHLDLSRNKLRDAATICIAEALKTNKGLVSLDLSCNNIMDEGGSAIAMFLKSNSTLRELRLRRNCMSNVTGDLLDEQLRSNTSLENMDITYNDFRYKCLLGIRATLARNAETNKGLVVPKLKAEVEGLSFKEKELAQAEDEIEMERRIIKDRSEQLLRRKEEARVTVEKARRDIVDIEKTLATVQGRMYAAEEVLHRTEERVSNGMATINARMSNMEARLQQERDRVERANREMDRVRRQLKQLEEAEAARLRPLLTELSIAEEDRNREMKACQYEGDKLATLELARKELEVKLGISARNAVLRTPTSRSSGKSPSRSPLGSPQRSSRR
Protein: Phosphatase (Q5A7R0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Protein transport protein Sec61 subunit beta
- Transcription initiation factor IIF subunit alpha
- Phosphatidate phosphatase
- Cyclic nucleotide-binding domain-containing protein
Sequence:
MGLLSSLLCCSIESKDDNDDKVHRPSTSNGIATTTSNKSNAAVTSASSKGNSSRNNQQDKAKKINTTTTKTTKANTTIIPTTNTSKSQSKNTPTRHGKDANTNENNSDLTKDNDIDVMGDEDEDEEDEVDALKPSKKDLLDDDQSINEIETIANTNDESNNNTPKSSNDTTKTDTNNTKINTSDIITQVPENGGAYTTTNSSNNYQKESRNSVQKNETRNGEDDDEEEDEDEDDDEDDESLEDLTKLQDGQAFNPETGYLLGKKDKNFGNKKCLILDLDETLVHSSFKYLRNADFVIPVEIDNQIHHVYVVKRPGVDEFLQKMGKLYEVVVFTASVSKYGDPLLDKLDIYNSVHHRLFRDSCYNYQGNFIKNLSQIGRPLEDTIIIDNSPASYIFHPDHSIPISSWFSDSHDNELLDLIPFLEDLAKPIVDDVGLVLDISL
Protein: Ubiquitin conjugating enzyme E2 N (F8VSD4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKARAWTRLYAMNNI
Protein: Podocin (Q91X05)
Organism: Mus musculus (Mouse)
Function: Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Nephrin
- CD2-associated protein
- Short transient receptor potential channel 6
- Tight junction protein 1
- Cadherin-3
- Alpha-actinin-4
- Synaptopodin
- FAT atypical cadherin 1
- Kin of IRRE-like protein 1
- Wilms tumor protein homolog
Sequence:
MDSRARSSSREAHGRSSRSSSRDDKKAKAGRGSRGRARPDAGAERQSTGRTATRGEPRAPAATATVVDVDEVRGPGEEGTEVVALLESERPEEGIKPSGLGACEWLLVLASLIFIIMTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASLLLSSLAHVSKAIQFLVQTTMKRLLAHRSLTEILLERKSIAQDVKVALDAVTCIWGIKVERTEIKDVRLPAGLQHSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPATVVLPLPFDMLSLLSSPGNRAQGSINYPSSSKPVEPLNPKKKDSPML
Protein: Aluminum induced protein with YGL and LRDR motifs (Putative aluminium-induced protein) (Q94BR2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein EXORDIUM-like 4
Sequence:
MLGIFSGAIVSPPEELVAAGSRTPSPKTTGSTLVNRFVEKNPSAVSVQVGDYVQLAYSHHNESPLRPRSFGAKDEIFCLFQGSLDNLGSLKQQYGLAKNANEVLLVIEAYKTLRDRAPYPANHVVAHLSGDFAFVVFDKSTSTLFVASDQVGKVPLYWGITADGYVAFADDVDLLKGACGKSLASFPQGCYYSTALGGLRSFENPKNKITAVPANEGEIWGATFKVEGATVLAD
Protein: Uncharacterized protein C23A1.02c (O42841)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein CASP
- Fumarate reductase
- GDP-mannose transporter
Sequence:
MFARHPNLLWLNKQLSILHYLCLVFLAVYYAYPLLFGIMPRKLQLEDENSFVIMGVADPQIEGNHKIEANGFFKGTLDLWGNDLFLRHLVHMNQFWGQPDAMILLGDLVSFQHLDNEEFNKRAKRLKKITGAKNFWQVGNSSLPARTFENGNIPVWTIAGNHDIGYGCESSDAQISKWEQAMGPVNWVSHFNVSKFPVRVIGINSLSLDDVQFYDANPSDIINSKSFSSLGILALSKEARDAWQFLFDIALEPSIPTILFTHVPLYKPANVCVDEPRIVRQLDFRVKSQNHLSYNTTMKIFELIPSIKLVLSGHDHMGCDYEHPNGAIEHTLPSAMGYFGGNIGFVKLIATNDVLTESSKNTPSVVTFLIQKLIGQRWKKASLKQSKFSSDIYATYTLSHGGPSYIWWALHISVCVLTILRLLVISLQHI
Protein: H-2 class II histocompatibility antigen, A-F alpha chain (P14435)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
EDDIEADHVGFYGISVYQSPGDIGQYTFEFDGDEWFYVDLDKKETVWRLPEFGQLTSFDPQGGLQEIATGKHNLGILTKRSNFTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFIIQGLRSGGTSRHPGPL
Protein: Secreted effector protein SopD (Salmonella outer protein D) (P40722)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to replication in macrophages. Plays a role, cooperatively with SopB, in membrane fission and macropinosome formation during invasion.
Subcellular location: Secreted. Host cytoplasm. Host cell membrane. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 T3SS), and delivered into the host cell (Probable). Membrane-associated in transfected cells. Recruited to the bacterial invasion site, and this recruitment requires the phosphatase activity of SopB. {ECO:0000305}.
Interaction partners:
- Guanine nucleotide exchange factor sopE2
- Cell invasion protein SipA
- Inositol phosphate phosphatase SopB
- E3 ubiquitin-protein ligase SopA
- Cell invasion protein SipD
- SPI-1 type 3 secretion system translocon protein SctE
- SPI-1 type 3 secretion system translocon protein SctB
- E3 ubiquitin-protein ligase SlrP
- Secreted effector protein SptP
- Inner membrane protein
Sequence:
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
Protein: General alpha-glucoside permease (O14091)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Responsible for the transport of maltose and sucrose into the cell, with the concomitant uptake of protons (symport system).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized Na
- Uncharacterized kinase C24B10.02c
- Glutathione S-transferase omega-like 2
- Inositol phosphoceramide mannosyltransferase 1
- O-glycoside alpha-1,2-mannosyltransferase omh1
- Glutathione S-transferase 3
- NADH kinase pos5, mitochondrial
- Inositol phosphoceramide mannosyltransferase 2
- Inositol phosphoceramide mannosyltransferase 3
Sequence:
MSVDENQLENGQLLSSENEASSPFKESIPSRSSLYLIALTVSLLGVQLTWSVELGYGTPYLFSLGLRKEWTSIIWIAGPLTGILIQPIAGILSDRVNSRIGRRRPFMLCASLLGTFSLFLMGWAPDICLFIFSNEVLMKRVTIVLATISIYLLDVAVNVVMASTRSLIVDSVRSDQQHEANSWAGRMIGVGNVLGYLLGYLPLYRIFSFLNFTQLQVFCVLASISLVLTVTITTIFVSERRFPPVEHEKSVAGEIFEFFTTMRQSITALPFTLKRICFVQFFAYFGWFPFLFYITTYVGILYLRHAPKGHEEDWDMATRQGSFALLLFAIISLAANTALPLLLEDTEDDEEDESSDASNNEYNIQERNDLGNIRTGTNTPRLGNLSETTSFRSENEPSRRRLLPSSRSIMTTISSKVQIKGLTLPILWLSSHVLFGVCMLSTIFLQTSWQAQAMVAICGLSWACTLWIPYSLFSSEIGKLGLRESSGKMIGVHNVFISAPQVLSTIIATIVFIQSEGSHRDIADNSIAWVLRIGGISAFLAAYQCRHLLPINF
Protein: Pre-mRNA-splicing factor cwf4 (Complexed with cdc5 protein 4) (P87312)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Pre-mRNA-splicing factor spp42
- Small nuclear ribonucleoprotein F
- Pre-mRNA-splicing factor cwf14
- Pre-mRNA-splicing factor cwf15
- Pre-mRNA-splicing factor syf2
- Pre-mRNA-splicing factor cwf12
- Pre-mRNA-splicing factor cwf5
- Pre-mRNA-processing protein 45
- U2 small nuclear ribonucleoprotein A'
- Pre-mRNA-processing factor 17
Sequence:
MTSEAPRVKNKNPAPIQISAEQLLREAVERQDVAFVPPKINITDLEELQEFQGRKRKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALDVDSTYIPLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERWLKWEPDENCWMSYIRMERRYHENERARGIYERFVVVHPEVTNWLRWARFEEECGNAANVRQVYLAAIDALGQEFLNERFFIAFAKFEIRQKEYERARTIFKYAIDFMPRSKSMELYKEYTHFEKQFGDHLGVESTVLDKRRLQYEKLLKDSPYDYDTWLDLLKLEESAGDINTIRETYEKAIAKVPEVVEKNAWRRYVYIWLNYCLFEEIDVKDVDRARKVYQEALKLIPHKKFTFAKLWLMYAMFELRQRKIDVARKTLGRALGMCPKPKLFRGYIEFEDAIKQFDRCRILYEKWILYDPEACAPWLGYAALETKLGDSDRARALYNLAVNQPILETPELVWKAYIDFEFEEMEYGKARSIYQQLLRTAPHVKVWISFANFEIAHLEDDDEEPPNEEVASPTAVVRARNVFENALAHLRQQGLKEERVVLLEAWKQFEAMHGTEDTRKHVSSLMPQVVKKRRRLEDGSFEEYLDYLFPDTATDQGDKMRKMLELSRKWKEEMAKKKLEA
Protein: Uncharacterized protein (Q57UW1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPARPNEEQYTPEMLQLRVKQGLQKRKKCALCLHVFHVNELPGAITHKSILELRKKWGLDVRRGDRMPPPSQLYKREELCVFCMQFFGTSGSTQSQQQLLASTRGGMPARLTLR
Protein: Cytoplasmic dynein intermediate chain (Q5BDC6)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Dynein light chain, cytoplasmic
- Dynein heavy chain, cytoplasmic
- Dynein light chain
- Dynein light intermediate chain
- P150 dynactin NUDM
- Dynamitin homolog
- Actin-related protein
- Nuclear distribution protein nudF
- Rhodopsin family protein
- Urease
Sequence:
MSSAANQQRKAEILAKKAKLAELKRQRELRQKEFSQSRASTGDASEVVSPVPSRSDSRAELDDLISRLVDRPGSAAVSGADGLSRKGSRPNSVLSASQLSGDNTEALSPPTRPLSQSIAVQTVGTEPFVAIPELQPAPEAKPEVVTYNKGVQTDDLRQGEQDAASVDSDAGETPDFKSSSKKQRERDEEIRKKLREEIEEELRATQESAKNESGADASIRYPLRQLDDDELKAVTSSEDFLDFVERSAKVIERALDEEYDVLADYELGGMDAELEDDDEHGKKKRGIKEVCQFWDERWSKKRMISDICFSPKFPELVLASYTKNPSAPHEPDGLVQIWNQHLHSRPEYVFHSTSDILTAKFSPFHPNIIVGGSYSGQVLLWDTRSSRAGGGAPVQKTPLTGAGHTHPVYSISIVGTQNAHNIITASTDGVVCGWTVDMLSQPQEYLELSTPPPSKTEDLAPTTISFPQSDPTFFIVGTEEGGIYPCHRYDRAGAKAGTDHRLAYRGHAAPIMSTAFHPARGPVDLGDLMLSSSLDWSVKLWRIRPPAATAPAATSGITDTQVVTPILDINREDVVYDARWSPHRPGVFSLVDGAGNLEVWDLYTDTEVPAVRTTPSKGRAGVLSRSLNKVAWEEREGRRLATGGLDGVVTVFEVGRGLSGTPDDVPSEEWTGMKRLVGKLEQKDKDRMS
Protein: Voltage-dependent calcium channel gamma-4 subunit (Neuronal voltage-gated calcium channel gamma-4 subunit) (Transmembrane AMPAR regulatory protein gamma-4) (TARP gamma-4) (Q9JJV4)
Organism: Mus musculus (Mouse)
Function: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11389205}; Multi-pass membrane protein {ECO:0000269|PubMed:11389205}.
Interaction partners:
- Glutamate receptor 2
- Voltage-dependent calcium channel gamma-1 subunit
- Glutamate receptor 4
- Glutamate receptor 1
- Voltage-dependent R-type calcium channel subunit alpha-1E
- Glutamate receptor 3
- Voltage-dependent L-type calcium channel subunit alpha-1D
- Protein shisa-9
- Disks large homolog 4
- Protein shisa-6
Sequence:
MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIYRGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQDAGFLQMHDFFQQDLKEGFHVSMLNRRTTPV
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q384U2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MPVLPPWRQRTSIFHRSEGRVQSVDATRISLVAAAGLVASQSATFTVLYLFLPEGLAGLTHLMVAAVLFNAFMLWNWGSDPGFVTSSEEPSTARERAIRRWCSVCRLLQPLRTKHCDKCGRCVRKYDHHCYCIGGCVGEFNHVRFVLTLASAVPYFVLLPPALLKCFSLGDIIDLDRVISRNIVPFIFVAYTTIQLVLVLSLLGLHCTLLLNNKTTWELSSRGRITYLDSRAANPFNKGIVQNVYFLFRRKPINWYSVLEEDECALV
Protein: Plasma membrane ATPase (EC 7.1.2.1) (Q6FXU5)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU362083}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362083}. Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
- Inorganic pyrophosphatase
- inorganic diphosphatase
- Phosphoglycerate kinase
Sequence:
MSDVESNNEKPPQDVYEDEEMSEDDDIDALIEELQSHHGMGDDDDSEDEGHHTGSARVVPEEYLQTDPSYGLTSDEVAHRRKKYGLNQMADERESMIVKFVMFFVGPIQFVMEAAAILAAGLSDWVDFGVICGLLMLNACVGFIQEFQAGSIVDELKKTLANVAVVIRDGQLVEVPANEVVPGDILQLEDGTIIPADGRLVTENCFLQVDQSAITGESLAVDKGYGDQTFSSSTVKRGEAFMVVTATGDNTFVGRAAALVNKASGGQGHFTEVLNGIGILLLVLVIVTLLGVWAACFYRTDNIVKILRFTLGITIIGVPVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLHEPYTVEGVSADDLMLTACLAASRKKKGLDAIDKAFLKSLINYPKAKDALTKYKVIEFHPFDPVSKKVTAVVESPEGERIVCVKGAPLFVLKTVEEDHPIPEDVHENYENKVAELASRGFRALGVARKRGEGHWEILGVMPCMDPPRDDTAETVNEARRLGLRVKMLTGDAVGIAKETCRQLGLGTNIYNAERLGLGGGGDMPGSELADFVENADGFAEVFPQHKYKVVEILQNRGYLVAMTGDGVNDAPSLKKADTGIAVEGASDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSLHLELFLGLWIIILNHSLDIELIVFIAIFADVATLAIAYDNAPFSQTPVKWNLPRLWGMSIILGIVLAIGTWICLTTMFLPRGGIIQNFGSIDGVLFLQISLTENWLIFVTRAVGPFWSSIPSWQLAGAVFAVDIIATMFTLFGWFSQNWTDIVTVVKIYIWSIGVFCVLGGFYYIMSESVVFDRLMNGKPLKEEKSTRSVEDFLAAMQRVSTQHEKEN
Protein: Small ribosomal subunit protein eS17 (40S ribosomal protein S17) (P08708)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23636399}. Nucleus, nucleolus {ECO:0000269|PubMed:34516797}.
Interaction partners:
- Small ribosomal subunit protein eS24
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein eL13
- Small ribosomal subunit protein eS10
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein eL8
- Large ribosomal subunit protein eL6
Sequence:
MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV
Protein: Regulator of MON1-CCZ1 complex (Colon cancer-associated protein Mic1) (Mic-1) (WD repeat-containing protein 98) (Q96DM3)
Organism: Homo sapiens (Human)
Function: Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization.
Subcellular location: Lysosome membrane {ECO:0000269|PubMed:17897319}. Late endosome membrane {ECO:0000269|PubMed:29038162}.
Interaction partners:
- Vacuolar fusion protein CCZ1 homolog B
- Vacuolar fusion protein MON1 homolog B
- Vacuolar fusion protein MON1 homolog A
- Sodium-dependent phosphate transporter 2
- Laminin subunit gamma-1
- Solute carrier family 53 member 1
Sequence:
MGEEDYYLELCERPVQFEKANPVNCVFFDEANKQVFAVRSGGATGVVVKGPDDRNPISFRMDDKGEVKCIKFSLENKILAVQRTSKTVDFCNFIPDNSQLEYTQECKTKNANILGFCWTSSTEIVFITDQGIEFYQVLPEKRSLKLLKSHNLNVNWYMYCPESAVILLSTTVLENVLQPFHFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAEVVLYHLPREGACKKMHILKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSVTFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDIIISASQGYLWNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEYKKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFKQIFGDQALMRPTTF
Protein: Protein arginine N-methyltransferase PRMT10 (EC 2.1.1.319) (Q9MAT5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. Essential for regulating flowering time.
Interaction partners:
- Histone H4
- Protein arginine N-methyltransferase 1.5
- rRNA 2'-O-methyltransferase fibrillarin 2
- Lysine-specific demethylase REF6
- Protein arginine N-methyltransferase 1.6
- Transmembrane protein
Sequence:
MRSSQNGGAMGGRAAGTGGGGPSAPVDKEVDYAQYFCTYSFLYHQKDMLSDRVRMDAYFNAVFQNKHHFEGKTVLDVGTGSGILAIWSAQAGARKVYAVEATKMADHARALVKANNLDHIVEVIEGSVEDISLPEKVDVIISEWMGYFLLRESMFDSVISARDRWLKPTGVMYPSHARMWLAPIKSNIADRKRNDFDGAMADWHNFSDEIKSYYGVDMGVLTKPFAEEQEKYYIQTAMWNDLNPQQIIGTPTIVKEMDCLTASVSEIEEVRSNVTSVINMEHTRLCGFGGWFDVQFSGRKEDPAQQEIELTTAPSEQHCTHWGQQVFIMSNPINVEEGDNLNLGLLMSRSKENHRLMEIELNCEIKEASGNPKESFKKTYFIE
Protein: B1 bradykinin receptor (B1R) (BK-1 receptor) (Kinin B1 receptor) (KB1) (P97583)
Organism: Rattus norvegicus (Rat)
Function: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P46663}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Kininogen-1
- Angiotensinogen
- B2 bradykinin receptor
- Guanine nucleotide-binding protein G
- Endothelin-1
- Guanine nucleotide-binding protein subunit alpha-11
- Prothrombin
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
- Carboxypeptidase M
Sequence:
MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSFFLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLCRVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSIPTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLRGQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEITDLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL
Protein: DENN domain-containing protein 1C (Connecdenn 3) (Protein FAM31C) (Q8IV53)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:20154091}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:20154091}.
Interaction partners:
- Ras-related protein Rab-35
- Ras-related protein Rab-13
- Clathrin heavy chain 1
Sequence:
MESRAEGGSPAVFDWFFEAACPASLQEDPPILRQFPPDFRDQEAMQMVPKFCFPFDVEREPPSPAVQHFTFALTDLAGNRRFGFCRLRAGTQSCLCILSHLPWFEVFYKLLNTVGDLLAQDQVTEAEELLQNLFQQSLSGPQASVGLELGSGVTVSSGQGIPPPTRGNSKPLSCFVAPDSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVVLNVDANTLETTFNDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFSEEVFLAQKPGAPLQAFHRRAVHLQLFKQFIEARLEKLNKGEGFSDQFEQEITGCGASSGALRSYQLWADNLKKGGGALLHSVKAKTQPAVKNMYRSAKSGLKGVQSLLMYKDGDSVLQRGGSLRAPALPSRSDRLQQRLPITQHFGKNRPLRPSRRRQLEEGTSEPPGAGTPPLSPEDEGCPWAEEALDSSFLGSGEELDLLSEILDSLSMGAKSAGSLRPSQSLDCCHRGDLDSCFSLPNIPRWQPDDKKLPEPEPQPLSLPSLQNASSLDATSSSKDSRSQLIPSESDQEVTSPSQSSTASADPSIWGDPKPSPLTEPLILHLTPSHKAAEDSTAQENPTPWLSTAPTEPSPPESPQILAPTKPNFDIAWTSQPLDPSSDPSSLEDPRARPPKALLAERAHLQPREEPGALNSPATPTSNCQKSQPSSRPRVADLKKCFEG
Protein: Synaptopodin 2-like a (Synaptopodin 2-like protein isoform X2) (A0A140LH61)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MVAEEVIITLSGGAPWGFRLQGGIEHQKPLQVAKVRKRSKACRAGLREGDELMSINENSCGSLSHAQAMNLIDSMPGTLHIRVRRAMSPSSSRPHQSSVRQIHRGTLMSPTGRSGLTSPPGSEAYYGETDSDADVAAHERHRKPKRRSPSNSPGKAGRASPEGAETSEMSGYDSASDAQMYKLLGPNKREDTLPGVARREVIYQPPLHGAWSSQTSTETSSMSADDQNPREGLMEEDSGFQEPTNIPPLVSPERAKEALMLSSRSQLVPMVGPVDNPVDEELTLTYMDKAKQAKLNRGETITDKQVKEARSKCRTIASLLTDAPNPHSKGVLMFKKRRQRSKKYTLTSFGSVDEDMRQDSQEEDGIFPGSESEFDEEGFSAAPDPTWDSDYLEMLEKRCASRGQEGDGGALSPGLSDTSGKGAQLFEQQRKRAEEHARKIEAAQEQLQSQMLGISLKEAQALPPLQTAHPDPLTKLNVQPPPVAPKPARPSTTLYHDVQAAEAQNNKTQMNTPQTIPTVPVMVNGDASNTTVTAPSVMPKTNLSVLSTETVMPPPPTPLPELPASSVLNRTARPFAPGCITNRAATAPVVFRPAVSKKTPRPVSVAVVAPPFPAASEEHVMCVTPAIFGTQVTMSQMNANVSNEIIPTQPLAQGTSIPPPAAVSVESYSQPAFQCSAMESIQVASLPRVQAQKPTVPMIAETIVPPDDMVTSLATDMHPKGITISSQTSSILTPTASETTSSPVIPLSPVVYREKPASVGGRTGILQDARRRSAYKPMFKMPDSKKNSPNPELLTMVQNLDDRPSHGYPEPDNIVYNIDENRTRVPPPVAPKPRVIPEMSQIPQAEGKGAELFARRQSRMDQFVVDTPYLQPATLQHQQSQSVIDFIQPREPSPTPSQWKYSPNVRAPPPIGYNPLLSPSCPVGVQRAGAKVSEGSAKGSKGSYGVPKEGIKALDFMRRQPYQLNPAMFSFGGGIGTQSSIPSYQRQQREGHTLTPPKQIPVKAARVYEIKRFSTPTPMSAPTLNPTVIIPRSQTTLGERISRSDMTSPAPEPVPESSLAPSRAPGLPELPKISSVPIPHPMPYSPPVPISSMSNLSYSGLQAAKQFKSAPELSALPPNPLKSPIQVPKPHFIATRAGVQPRVWRPGTLPH
Protein: Protein FAM167A (Q96KS9)
Organism: Homo sapiens (Human)
Interaction partners:
- Tyrosine-protein kinase Blk
- Myotubularin-related protein 9
- XK-related protein 6
- Phosphatidylinositol-3-phosphate phosphatase MTMR7
Sequence:
MSVPQIHVEEVGAEEGAGAAAPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEHTWPFPRPAAEPQASLEEGERGGQEPLLPLREAGQHPPSARSASQGARPLSTGKLEGFQSIDEAIAWLRKELTEMRLQDQQLARQLMRLRGDINKLKIEHTCRLHRRMLNDATYELEERDELADLFCDSPLASSFSLSTPLKLIGVTKMNINSRRFSLC
Protein: F-box protein At5g03970 (Q94A64)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transcription regulator
- Transcription regulator NOT2/NOT3/NOT5 family protein
Sequence:
MSCSARLKTNLGMTSALSTHEVLNSNDTMCEILILLPPETIYKLILVSKRWLEIIASPCFRHTYLAKWKPNFELIGFFVCSSMYLGRRIDGTRRPRAEPSLPLLSTSSIGDEIESSGILKKLGYYIDSADGLLLCGRHPKAYYLWDPSTQKQQQLPRPRVHFEELCMSLISEDSPDQGFSYKVVRAECVAFPVNSTKVKVETFSSKTSTWSYSELICLEPLSLSPWTPGRVIKGVVYWHARGGKIAIYDSNSEEKRIDVIKLPKTYDYDEQVLGETDDGSLQYGWSNKSVMEVWKLEKVGNVLEWNLLFKVNFKAMWKMNQAVATRFSTWTKETQLLALFNQKSDLVYIRCDTQIFIYHTETKRVEVVQYQGRKSTLVWDFNKVVPYFRRTWPCSPLFENNAMMIDTPQCNASSAGSN