wanglab/gogpt-training-data huggingface dataset:
Protein: Homeobox protein Hox-A10 (Homeobox protein Hox-1.8) (Homeobox protein Hox-1H) (PL) (P31260)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-A9
- Homeobox protein Hox-A5
- Pre-B-cell leukemia transcription factor 1
- Homeobox protein Hox-A11
- Homeobox protein Meis1
- Homeobox protein Hox-A7
- Pre-B-cell leukemia transcription factor 2
- Homeobox protein Hox-A13
- Homeobox protein Hox-A3
Sequence:
MSARKGYLLPSPNYPTTMSCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPPPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS
Protein: GldJ (A5FJM9)
Organism: Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / BCRC 14874 / CCUG 350202 / NBRC 14942 / NCIMB 11054 / UW101) (Cytophaga johnsonae)
Interaction partners:
- GldD
- GldN
- GldB
- GldL
- SprA
- GldG
- SprE
- SprT
- GldM
- Gliding motility lipoprotein GldH
Sequence:
MKVNKIVVLQLMMSMVLMLGTASCSKKSSSSHASRATGWDVDSQNGTAARNAGKKQQAGPGLVFVEGGTFTMGKVQDDVMHDWNNTPTQQHVQSFYMDETEVTNGMYLEYLEWLKKVFPPTEENYKNIYEGASPDTLVWRNRLGYNETMTNNYLRHPSYANYPVVGVNWIQAVEFSKWRTDRVNEAVLEKNGYLKKGAKTNDVTAESLFNTEAYVASPSTTYGGNEELVLKKNPNGRRPKAGKDGVVPEEKNVYAQRSSGIILPEYRLPTEAEWEYAAAADVGQREYNIYKGQKKYPWSGDYTRSNKRKNRGDQLANFKQGNGDYGGIAGWSDDGADITNAVKSYAANDFGLYDMAGNVAEWVADVYRPIIDNEANDFNYYRGNQYAKNKIGKDGKIEIVSTATIKYDTLSNGKVVARNLPGEIAQVPVDEQETYLRTNFSTSDNINYRDGDKQSSRYFDFGDSESGSKADQAMYNSPKHNITTDSLGKMIRKYDNSSKRTTLIDDKVRVYKGGSWRDRAYWLDPAQRRYFPQDMATDYIGFRCAMSRVGAKTERRKSPRN
Protein: Agamous-like MADS-box protein AGL82 (Q9FIM0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that may function in the maintenance of the proper function of the central cell in pollen tube attraction.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
Interaction partners:
- AGAMOUS-like 102
- AGAMOUS-like 33
- Agamous-like MADS-box protein AGL66
- Agamous-like MADS-box protein AGL29
- AGAMOUS-like 85
- Agamous-like MADS-box protein AGL65
- AGAMOUS-like 59
- Agamous-like MADS-box protein AGL104
- AGAMOUS-like 95
- Agamous-like MADS-box protein AGL61
Sequence:
MVPKVVDLQRIANDKTRITTYKKRKASLYKKAQEFSTLCGVETCLIVYGPTKATDVVISEPEIWPKDETKVRAIIRKYKDTVSTSCRKETNVETFVNDVGKGNEVVTKKRVKRENKYSSWEEKLDKCSREQLHGIFCAVDSKLNEAVTRQERSMFRVNHQAMDTPFPQNLMDQQFMPQYFHEQPQFQGFPNNFNNMGFSLISPHDGQIQMDPNLMEKWTDLALTQSLMMSKGNDGTQFMQRQEQPYYNREQVVSRSAGFNVNPFMGYQVPFNIPNWRLSGNQVENWELSGKKTI
Protein: Growth factor independent 1B transcriptional repressor (A0A1B0GTD0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAPAPEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQAAPMECPVPQGIPAGSSPEPAPDPPGPHFLRQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK
Protein: Uncharacterized protein C7D4.12c (O14267)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MDGNRRVRFNTDRRPYLSPLQTSFPSSTSFQTPTFLIEEDDEDTEDDDGPQVLPVHRAPSPAAFRKRGSITSMDQYLVNMPAVPSPTASKVGLLDARNTDVESYAASYKTQSSSNSVNSLPMRRPTLDRSYSAPMIAAKNLQSDPEKMSNVESTNELPSTTTEAYKLVAAHTAARLEHMRLNALKAANDEGEDVKDNEQDDNIDESDPFANPKASYRGGVLSNLLKLYTNSNTVTSSRISLKHTDPTKWQKHAKRTASSNSLTDLLHASNQTFMAPASGLQSTEEIPQFSKTGHSRGRKFNFHHHSRKNSGLNEEYKITIHLADILQRQKYILKLCRALMVYGAPSHRLEEHMASAAKVLEIEGQFLYIPGCMIVSFGDVNTHTSDMHIVRVNQTIDLGRLKLVHDIYKAVLHDRMGVEEAIRGLDEIFKSPPYFRTWILVVFYGFASATILPMSFQGGWIDLPIAFILGCLVGILQHYIAPRSTMYNSLFEVTGSIITSFLSRAFGSIRYSGGRRFCFSALAEGAIVLILPGYIVLCGSLELQSKNIVAGGVRMFYAIIYSLFLSFGISIGAALYGWMDHNATDSTSCPVSTQMDDKWKILFVPLFTLCLLIVNQARPSQWPVSIFISCAGYVVNYFTAKHFGSNPIANAIGSFAIGCLGNIYSRLGRGVAFAAVLPAIFVQVPSGLAAQGGISSGIEVATSLTNNTYNTSSSSTLDVNSLKFGLVMVQIAIGISVGLFASALVVYPFGKRRSGLFSF
Protein: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II) (Q961U0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323}.
Interaction partners:
- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Exostosin-3
Sequence:
MSKMRGRILIPLPNTGAMGRKRNNFYMRSLFLLALGIFGLLQYNNFNYLDSRDNVLGDAVTNDSDDAILAMVPATLHKYLTPHSRNHSASGAGALNGAALLLNASSPGAATASTISFDVYHPPNITEIKRQIVRYNDMQMVLNEDVFGPLQNDSVIIVVQVHTRITYLRHLIVSLAQARDISKVLLVFSHDYYDDDINDLVQQIDFCKVMQIFYPYSIQTHPNEYPGVDPNDCPRNIKKEQALITNCNNAMYPDLYGHYREAKFTQTKHHWIWKANRVFNELEVTRYHTGLVLFLEEDHYVAEDFLYLLAMMQQRTKDLCPQCNVLSLGTYLKTFNYYTYHSKTNKKSYASSLISTNSLLGYNRNNNRNSVQLAVSSSYSSSSSAQSPPPSKVYVGDTSDNQRASDSSSRRGNLINTVTDTATATAATSDTSNNEQSSHSSSKNGAQTWNYHVLPSLYSVYQKVEVMPWVSSKHNMGFAFNRTTWSNIRKCARHFCTYDDYNWDWSLQHVSQQCLRRKLHAMIVKGPRVFHIGECGVHHKNKNCESNQVISKVQHVLRIARNSHQLFPRSLTLTVPSLMKKSKLRKGNGGWGDMRDHELCLNMTLATR
Protein: Ciliary microtubule inner protein 5 (Q96LR7)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:38538594}.
Interaction partners:
Sequence:
MGSHPTPGLQRTTSAGYRLPPTRPPASVSPAARGGPMASRGLAGGCQAPQALKAQRVAQGAACDGVQQDQLWRELLEAERRGQQRWIQNWSFLKDYDPMGNKKEPEKLPDHVPLFSDTVPSSTNQVVGSRLDTPLGQTLIRMDFFFTEGARKKKLEDQMQPI
Protein: FYVE, RhoGEF and PH domain containing 5 (H7C0G2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XQIPPRRPARAGAFTKLFEDQSRALSTANENDGYVDMSSFNAFESKQQSADQDAESAYTEPYKVCPISSAAPKEDLTSDEEQRSSEEEDSASRDPSVTHKDFHGAVMRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCLHSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQ
Protein: UDP-glucuronosyltransferase (EC 2.4.1.17) (Q8VCN3)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167, ECO:0000256|RuleBase:RU362059}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167, ECO:0000256|RuleBase:RU362059}.
Interaction partners:
- Cytochrome P450 2E1
- Cytochrome P450 1A1
- Cytochrome P450 1B1
- Beta-glucuronidase
- UDP-glucose 6-dehydrogenase
- Sulfotransferase 1E1
- Aromatase
- Aldo-keto reductase family 1 member D1
- 11-beta-hydroxysteroid dehydrogenase 1
- Carbonyl reductase 1])
Sequence:
MPGKWISALLLLQISCCFRSVKCGKVLVWPMEFSHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFPTSVTKDDLENFFIQLLNVWTYELSRDTCLSYSPLMQNMFDELSGYYLSLCKDVVSNRQLMTKLQESKFDVLLSDPVAFGGELIAELLHIPFLYSLRFTAGYRIEKSSGRFLLPPSYVPVILSGLGGQMTFIERVKNMICMLYFDFWFQMPNDKKWDSFYTEYLGRPTTLAETMGQAEMWLIRSNWDLEFPHPTLPNVDYVGGLHCKPAKPLPKDMEEYVQSSGDHGVVVFSLGSMVSNITEEKVNAIAWALAQIPQKVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFITHGGANSVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWVEFVMRHKNAKHLRPLGHNLTWYQYHSLDVIGFLLACVAATVVLTVKCLLFIYRFFVTKKKKMKNE
Protein: Os03g0639300 protein (Q6AUE8)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MNQFVPDWSNMGDASRTLGEDDNLIELLWCNGHVVMQSQNHHRKLPPRPPEKAAAAAVQEDEAGLWFPFALADSLEKDIFSDLFYEAPVAATAEAAPAGPGAGADGEGKTCKGDAAMAEEERGGPGAASEAPRELMPPPKSTNASCSRQQTMSLADGGDNAGDLSELVRARRSSGGAARRKAEAGGGGGGASSSMLSAIGSSICGSNQVQVQQRTASEPGRRGAPPSAVGSANAIPCGGRDHGHGHEATTVASSSGRSNCCFGTTTTTEPTSTSNRSSKRKRLDTTEDSESPSEVGVLPSNTNRDAH
Protein: START domain-containing protein (Q20440)
Organism: Caenorhabditis elegans
Interaction partners:
- START domain-containing protein 10
- Phosphatidylcholine transfer protein
- START domain-containing protein
- Ceramide transfer protein
- Steroidogenic acute regulatory-like protein 1
- START domain-containing protein
- Tensin homolog
- SH3 domain-containing protein
- Serpentine receptor class delta-45
- Serpentine Receptor, class H
Sequence:
MQNGHRSMKPRVQSMNILSIPLEPEFKSLPQNVPENIPVLRRRKYTKQQRKSLVIEPDISLILAAGQNQSSSSDDDDTKVQIDSNTLPQNRRKYAGRRNMKKRFYSTSNLKGNEDENDENSSKQIGTKSLSVRDLNGDNIDFNNRDSVKKWTSQIFAELESIPSSRRGSMEVTRAMTNPPPELMINLAPTLAPPSPMKRKRFPVFDEQEAGFQPIAPVPSPRRQQEDVVGPTFLRDLLTASCSRSPCSESNYSDRLATSDTATTQKASRASSFEWLENSGHGKYEQCSSDEADREVASIEMVKQTEVLQRKKTIEDLEESVNELQSLGNGSWFPHPPPPPAEARDQIYESLPASFRNRKSENRKNAVGSVYDNAAISSKPSSSETTSFSQQKPIIDRKPFSLENLPMVQRLTELSAAKKNADSKNEVAKRSNTFSLQLAERDAVDACSWLRKAGFSKYADQFEEGKLPIVASKDPTLLEADLRALNRRIDVLNRCHTMKVDSVPMRRRINNEFPRLDPMKIDDNSGYSSDSWRYGSVGGSHHSNTWSRPSGSDHHVYGGSLARMPNSTSSAWHHQMADPTRDSRKVLRTDWYDAQNTPPRGRNNDVLETASSAACVNELNSKLQRSQSERIKDRARAIMKKMDLRSTNKRPKETRGRPAPMNIGDPVLVSYDTPKNSIRSHHIDRPSILPERGRQLYPTSPYQAPSRSKSIAQNNRRGGLVFITPTSPNSLDTSFGYSDTNSSVVSSHRSNGESRRRELSMPPPSRHRVQMNGPSYPVMDGTLRRREIMPFDSYLYAGNPKMLERYDKTYESPRNLIPDRMYDDLDDLPLPKSTKTTNSNSTSNSNSLDNKKTDNISMFNDGYYTHEIKTALPRHHNILTTVKPENLKVNTEKIDIISSSDEPIGRTALTKRSDSGLGSSLSRSPSGPHTQRIRQSLLPYSNATSSSASAYSCCSWGSSTKLLDEQQPFFTDMVELARSIDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENLLDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSLFQLGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFMVPDGLDDSMDAEDDNPNLTELGLKGPRSFLVDRVIDLIRDHSDQWKNWTIEGSFRGIEISSKRPSDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHLEYVSAPDTDIHQYVVNETIGHPTKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVSATIFDQRFLIEPVSGGQSRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLRESFHLGDKGGPETNV
Protein: Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1) (P20807)
Organism: Homo sapiens (Human)
Function: Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53.
Subcellular location: Cytoplasm. Nucleus, nucleolus {ECO:0000269|PubMed:23357851, ECO:0000269|PubMed:27657329}.
Interaction partners:
- Titin
- Dysferlin
- Calpastatin
- Ribitol 5-phosphate transferase FKRP
- Filamin-C
- E3 ubiquitin-protein ligase TRIM32
- Telethonin
- Gamma-sarcoglycan
- E3 ubiquitin-protein ligase TRIM71
- Myopalladin
Sequence:
MPTVISASVAPRTAAEPRSPGPVPHPAQSKATEAGGGNPSGIYSAIISRNFPIIGVKEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADALQSDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Protein: At1g10770 (Plant invertase/pectin methylesterase inhibitor superfamily protein) (T16B5.9) (Q9SAC5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Pectinesterase inhibitor 2
- Invertase/pectin methylesterase inhibitor family protein
- Pectinesterase PPME1
- Plant invertase/pectin methylesterase inhibitor superfamily protein
- At5g50030
- Probable pectinesterase 67
- Probable pectinesterase/pectinesterase inhibitor 23
- Pectinesterase inhibitor 1
- Pectinesterase inhibitor 5
- Probable pectinesterase 49
Sequence:
MAGRDTFQLRFAAVAASAAVLIFLMAGQVAESRMINICSHTAYPSLCRPLVKRVTSPRKATHRTIQALEAKTKLALAETARFKNGNQAVSTCYETLGDAVYNLASARKSIRKRDVPAMNTYLTAAVSDYGACVDGFIETQQVNAIQNAVVDLRKISSNCLALSTLIR
Protein: RNA-binding (RRM/RBD/RNP motifs) family protein (F4I2E4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable receptor-like protein kinase At1g49730
- RING/FYVE/PHD zinc finger superfamily protein
- Putative BPI/LBP family protein At3g20270
- SWR1 complex subunit 6
- Peptidyl-prolyl cis-trans isomerase CYP57
- Protein DEHYDRATION-INDUCED 19 homolog 5
Sequence:
MAYQPVPGSGFHYLNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYGEILEAVVIADKNTGRSKGYGFVTFRDPEAARRACADPTPIIDGRRANCNLASLGRPRPPLPYAVIPNMPGRLRPASPYIGNVQGPRGSLIGNYPYQQPLPYNYQQGVVYPYGVTAYGPEYMYSQSQGLYSPYMGQQYLQVYGVPGAVNSPVYQYGQLSQTIPNGHGYTAVQGYSVPGSHILQLGGPTVSTMTTSSMPALQAPYPSGIPGPAPVQSHIIVHSPQFMQSTASDQTTSYS
Protein: Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit) (Q6FLU4)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity).
Interaction partners:
- Serine/threonine-protein phosphatase
- FK506-binding protein 1
- Candida glabrata strain CBS138 chromosome M complete sequence
- Candida glabrata strain CBS138 chromosome E complete sequence
- Candida glabrata strain CBS138 chromosome G complete sequence
- Calcium-channel protein CCH1
Sequence:
MGAAPSKIVETLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKNEFMSIPGVSANPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLKFAFKIYDIDKDGLISNGELFIVLKIMVGSNLDDKQLQQIVDRTIMENDLDGDGQLSFEEFKSAIETTEVAKSLTLQYSV
Protein: Sperm microtubule inner protein 6 (Ciliated bronchial epithelial protein 1) (Spermatid-specific manchette-related protein 1) (Testis development protein NYD-SP22) (Q2MH31)
Organism: Mus musculus (Mouse)
Function: May be involved in differentiation or function of ciliated cells (By similarity). May play a role in spermatogenesis.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18163442}. Nucleus {ECO:0000250|UniProtKB:Q8NCR6}. Cytoplasm {ECO:0000269|PubMed:18163442, ECO:0000269|PubMed:31504408}. Mitochondrion {ECO:0000269|PubMed:31504408}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37295417, ECO:0000305|PubMed:31504408}. Note=During spermatid elongation (step 10), localizes along the length of the manchette and later during the elongation process only at the distal ends of spermatid manchette (step 12). In late elongated spermatids (step 16), in the final steps of spermiogenesis, localization is restricted to the midpiece of the flagellum (PubMed:18163442, PubMed:31504408). Localizes at the contractile ring in dividing cells (PubMed:31504408). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines (By similarity). {ECO:0000250|UniProtKB:Q8NCR6, ECO:0000269|PubMed:18163442, ECO:0000269|PubMed:31504408}.
Interaction partners:
- Dynein light chain roadblock-type 2
Sequence:
MFLFSRKTKTPISTYSDSYRAPTSIKEVYKDPPLWAWEANKFVTPGLTQTMHRHVDPEALQKMTKCAAQDYTYKSSISGHPYLPEKYWLSPDEEDKCCPSYLDNDRYNTWKTSPCSNYWNKYTGCLPRLSKDTGMESVRGMPLEYPPKQERLNAYEREVVVNMLNSLSRNRTLPQIVPRCGCVDPLPGRLPYQGYESPCSGRHYCLRGMDYCTTREPSTERRLRPLCSQQPTECVALRSPARNAMCCYNSPAIILPVSQP
Protein: C15 (FI01111p) (Q7KS72)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Homeobox protein aristaless
Sequence:
MSSHEEDDHEHENEHGEEVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETPLSESLQSEQTRSSSSENLPFSISRLLSKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQGGVNGAPLAALHGLQPWAEASHAAGC
Protein: Uncharacterized protein C19C7.04c (O60153)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MTEVTKINPSTAITELEPYEMAQTNKEVPTTSLLSKDYYGHSIEEPDENNPTRWRYERPLDTVRAWQYLIDCDENFKTKPHREQNQYRPTADSFRPLSFASMESKLTQRLSRHLSKTSSRHSRL
Protein: Deadbeat, isoform D (R9PY71)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MARSQSKMIRAAMVVDDPNMVAWLPYLNFLRFLKRNFYPRTDLRRLLQVGLIRWIALSDAQKSESWRVWLAGKGINDAADYFAVLGMARKDVVQCDAPSTTAVLNRDAANRSRE
Protein: Alpha-2A adrenergic receptor (Alpha-2A adrenoreceptor) (Alpha-2A adrenoceptor) (Alpha-2AAR) (Q01338)
Organism: Mus musculus (Mouse)
Function: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Voltage-dependent P/Q-type calcium channel subunit alpha-1A
- Guanine nucleotide-binding protein G
- Alpha-2B adrenergic receptor
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-12
- Guanine nucleotide-binding protein subunit alpha-13
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Sodium-dependent serotonin transporter
- Guanine nucleotide-binding protein subunit alpha-11
Sequence:
MFRQEQPLAEGSFAPMGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGPTGAEAEPLPTQLNGAPGEPAPAGPRDGDALDLEESSSSEHAERPPGPRRPDRGPRAKGKTRASQVKPGDSLPRRGPGAAGPGASGSGHGEERGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPSQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
Protein: MYB-like DNA-binding domain protein (Myb domain protein 305) (Q9LK14)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Bidirectional sugar transporter SWEET9
Sequence:
MSLWGGMGGGWGMVEEGWRKGPWTAEEDRLLIDYVQLHGEGRWNSVARLAGLKRNGKSCRLRWVNYLRPDLKRGQITPHEETIILELHAKWGNRWSTIARSLPGRTDNEIKNYWRTHFKKKTKSPTNSAEKTKNRILKRQQFQQQRQMELQQEQQLLQFNQIDMKKIMSLLDDDNNNGDNTFSSSSSGESGALYVPHQITHSTTTSGCEPNSNGYYPVVPVTIPEANVNEDNAIWDGLWNLDFEGQGSFGGAACAPRKHYFQNMVIPFC
Protein: Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein 1) (Protein deglutamylase CCP1) (Q4U2V3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9UPW5}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q641K1}. Nucleus {ECO:0000250|UniProtKB:Q641K1}. Mitochondrion {ECO:0000250|UniProtKB:Q641K1}.
Interaction partners:
- N-alpha-acetyltransferase 35, NatC auxiliary subunit
Sequence:
MNKPKMAAEKSASRVLMLLSQLERLNEESRVSDNDAIRQVTGKILHLIQTQEKTRKEVGSKGSGGMEIILSSLENTRDLQTTLNILGILNELLTVGGGRRTGLFVSKGGTAILLQLLVSSSKDPPANEELMLHIHSLLVKVGPKDRKFGVKARLNGALNVTLNLAKHNLQNYKLLLPCLQVLRVYSSNSVNAVSLGKSGALEILFEIVGPFSKKSTTLLKVALDTLAALLKSGMNARRAVDRGYLPTLLAIYQDWHRNDTRHRHVIIRKSILGCIKNITNIKLGRKAFIEASGMRILYNTSTECLPVRTLDPLVNTSSLIMRKCFPKNRLPLPTIKSVFLYPLPHIPAGGPVAQLYNQPPGVDDVVDESDENEATEVDTENDTENEEDDTGHKTQNDDIETDINKLRPKQMNTRPFEELRVYEHFCREFTETFQDIDFEDSISAIPPSRVNSELHRPIIIPTTQSSPGLQNRRPLRESALPLKPEQSPLELDSISIAKRPDGRADADLVCSLGHLILDAAVNGGSVDGCQDDGGEQSVLEVPDTAALLPLHDPELYLEMVKSTRSVPGYTEVAYPDYFGHVALNLREPILERVYGVQRTKIFQDIERLIHSSDILDKVVYDLDNQSSPLTDNGESLKFNSKFESGNLRKAIQVRKFEYDLILNSDINSNHYHQWFYFEVGNMRPGVRYRFNIINCEKSNSQFNYGMQVIMYSVQEAINGSPHWVRTGSDICYYKNHFARSSIAAGGQKGKSYFTMTFTVTFQHKDDVCYFAYHYPYTYSMLKMHLQKLSALCTPEIYYRQEDLCETLGGNGCPLLTITAMPESSSDEHISQFRSRPVIFLSARVHPGETNSSWVMKGSLEFLMSCSPQAQSLRQSYIFKIMPMLNPDGVINGNHRCSLSGEDLNRQWQNPNAELHPTIYHAKSLLQYLRATGRTPLVFCDYHGHSRKKNVFMYGCSIKETMWQSSVNTSTCDLNEDLGYRTLPKLLSQMAPAFSLSSCSFVVERSKEATARVVVWREIGVQRSYTMESTLCGCDQGKYKGLQIGTSELEEMGSQFCLALLRLRRFTSPLELHNHNSHLLDMENELIDTRHIPNITSPTTYVLDEDEPAFLEEVDYSAESNDENDPELEPDLRDNHALPDPSSDSELSHQDSLT
Protein: Keratin Kb40 (Q6IFT3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSLSPCRAQRGFSAHSACSAFSGARGRTGFSSRSLSSSRRCRGSSCGRAWGAETRQGIRFGQGKGGPGFSQCPPGGIQAVTVDQSLLTPLKIEVDPQFQVVKTQETREIRSLNNQFASFIDKVRFLEQQNKVLETKWELLQQLQGNRSPQGLECIFETCLARLRQQLEELQRERRALDSELKTYQDQEDEYKSKYDQEAYKHASVQNDFVVLKKDVDEVFQSKMDLEGNLESLKEHVCFLTRLYEEELGQLKTQADDMSVVLSMDNNRCLDFSDIIAEVRARYEEITRTSKAEAEAVFQTKYQELQESAQLQGNSMKEAQVQISQLRQAIHRLQSQIGSLRKQNDSLQSAIADAEQQGEMAVRDAQAKLDELEAALRTAKQDMAQMLRDYQELMGTKLSLDVEIAMYRRLLESEECRISTEHTSQVTVSITEGSIVPGRTCGGQVVVPGRIGTGQVVMPGRECGGHVVMPGRGSGGQVTIPGRGSGGQVTVPRGECGGQVTMPGRGSGGQVTMPGRGSGGQVTIPGRGSGGQVTVPGRGSGGQVTIPGRGSGGQVTIPGRGSGGQVTVPGRGSGGQVTIPGRGSGGQVTIPGRESGGQVTIPGRESGGQVTMPGREYGGQVTIPGRESGGQVTMPGRGSGGQVTMPGRGSGGQVTVPGREYGGQVTVPGRGSGGQVTVPGREYGGQVTVPRGECGGQVTVPGREYGGQVTMPRGECGGQVTMPGREYGGQVTMPGRESGGQVTVPGREYGGQVTMPRGECGGQVTVPGREYGGQVTMPRGECGGSSDHAWKRIWRPGDRA
Protein: Collagen type I alpha 2 isoform 1 (A0A0S2Z3H5)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MLSFVDTRTLLLLAVTLCLATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRAQPENIPAKNWYRSSKDKKHVWLGETINAGSQFEYNVEGVTSKEMATQLAFMRLLANYASQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGADQEFFVDIGPVCFK
Protein: Homeobox protein ceh-13 (P17488)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeobox protein ceh-20
- Homeobox protein ceh-40
Sequence:
MSSTECYGAPPHNYYQDWPTTHSYYPSVPSSYSPLNHHPADIWAAHPSNYIMGNGHVSPPATASGLSPPASRSSNSSAELPTGVTASQHNTYKWMHTKRSQRPAAPKKKVIDENGTNRTNFTTHQLTELEKEFHTAKYVNRTRRTEIASNLKLQEAQVKIWFQNRRMKEKKREKEKAFLARNTWESNSPTSSCSGEDVKNFK