wanglab/gogpt-training-data huggingface dataset:
Protein: GH3 domain-containing protein (Q8N2G8)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q99J23}. Nucleus envelope {ECO:0000250|UniProtKB:Q99J23}.
Interaction partners:
- Caveolae-associated protein 1
- Hypocretin neuropeptide precursor
- Signal transducer and activator of transcription 5B
- ATP-dependent RNA helicase DHX58
- Signal transducer and activator of transcription 5A
Sequence:
MLLWPLLLLLLLLPTLALLRQQRSQDARLSWLAGLQHRVAWGALVWAATWQRRRLEQSTLHVHQSQQQALRWCLQGAQRPHCSLRRSTDISTFRNHLPLTKASQTQQEDSGEQPLPPTSNQDLGEASLQATLLGLAALNKAYPEVLAQGRTARVTLTSPWPRPLPWPGNTLGQVGTPGTKDPRALLLDALRSPGLRALEAGTAVELLDVFLGLETDGEELAGAIAAGNPGAPLRERAAELREALEQGPRGLALRLWPKLQVVVTLDAGGQAEAVAALGALWCQGLAFFSPAYAASGGVLGLNLQPEQPHGLYLLPPGAPFIELLPVKEGTQEEAASTLLLAEAQQGKEYELVLTDRASLTRCRLGDVVRVVGAYNQCPVVRFICRLDQTLSVRGEDIGEDLFSEALGRAVGQWAGAKLLDHGCVESSILDSSAGSAPHYEVFVALRGLRNLSEENRDKLDHCLQEASPRYKSLRFWGSVGPARVHLVGQGAFRALRAALAACPSSPFPPAMPRVLRHRHLAQCLQERVVS
Protein: Protein RhsD (P16919)
Organism: Escherichia coli (strain K12)
Function: Rhs elements have a nonessential function. They may play an important role in the natural ecology of the cell.
Interaction partners:
- O-antigen ligase
- Putative frv operon regulatory protein
- Putative lipopolysaccharide heptosyltransferase 4
- Uncharacterized protein YehI
Sequence:
MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMTSGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTKTPAPVGVFGPGWKAPSDIRLQLRDDGLILNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWGALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGMADRFGRTLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARTSSLSSSDSSRPLSASAFPDTLPGTEYGPDRGIRLSAVWLMHDPAYPESLPAAPLVRYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLSYRYLYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTRSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRREYDEPGRLVSETSRSGETVRYRYDDAHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQYDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVILWYYDESDRITHRTVNGEPAEQWQYDGHGWLTDISHLSEGHRVAVHYGYDDKGRLTGECQTVENPETGELLWQHETKHAYNEQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFGSMAGSNAAYELTSTYTPAGQLQSQHLNSLVYDRDYGWSDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLPDPELHPDSTLTVWPDNRIAEDAHYVYRHDEYGRLTEKTDRIPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDLTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYEPGSFTPLIRVETENGEREKAQRRSLAETLQQEGSENGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEYTPARKAHLYHCDHRGLPLALISEDGNTAWSAEYDEWGNQLNEENPHHVYQPYRLPGQQHDEESGLYYNRHRYYDPLQGRYITQDPMGLKGGWNLYQYPLNPLQQIDPMGLLQTWDDARSGACTGGVCGVLSRIIGPSKFDSTADAALDALKETQNRSLCNDMEYSGIVCKDTNGKYFASKAETDNLRKESYPLKRKCPTGTDRVAAYHTHGADSHGDYVDEFFSSSDKNLVRSKDNNLEAFYLATPDGRFEALNNKGEYIFIRNSVPGLSSVCIPYHD
Protein: Src kinase associated phosphoprotein 2 (C9JQ17)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MTTRSVLDVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYLQEFQDKGDAEDGEEYDDPFAGPPDTISLASERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDHSFLGFEWQKRW
Protein: Nucleoporin NUP188 (Nuclear pore protein NUP188) (G0SFH5)
Organism: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP188 probably plays an important role in NPC assembly and organization.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P52593}. Nucleus membrane {ECO:0000250|UniProtKB:P52593}; Peripheral membrane protein {ECO:0000250|UniProtKB:P52593}; Cytoplasmic side {ECO:0000250|UniProtKB:P52593}. Nucleus membrane {ECO:0000250|UniProtKB:P52593}; Peripheral membrane protein {ECO:0000250|UniProtKB:P52593}; Nucleoplasmic side {ECO:0000250|UniProtKB:P52593}. Note=Symmetric distribution. {ECO:0000250|UniProtKB:P52593}.
Interaction partners:
- Nucleoporin NIC96
- Nucleoporin NUP192
- Nucleoporin NUP145
- Nucleoporin NUP57
- Nucleoporin NUP170
- Nucleoporin NUP133
- Nucleoporin NUP49
- Nucleoporin NUP120
- Nucleoporin NUP84
- Nucleoporin NSP1
Sequence:
MATLTDRTYLPPLEDCLTGRTVILSWRLVASALEDADLARLTSPALSTFLRDGFVHELLKHPARVFEPKDLKQEFETKTSSIQTVAPGVDTIKKDALWLADAVAINQVAALRIVLIEYQTRAHSHLVLPLSTQDVANIQEAAGVGDAHASSILSLLNPASAVDAETMWCDFETEARRRERILATYLSERRSFTAAVDALVTFLLHSAPGQHKDLDSLRRALLKDAFAFDEDLDVPDRSKLLTMAPTYMNLVEDCIARAQALPAKLGESFKTEAFELDWLRTAITEAVHSLSIAFQALDLDTPYFAPHELLSEWFELMNSSLFLESILGFEVVADLAMPARSLVSAICLKMLNIDRTIQFLHDFDYPDGEEPYLLSSQTLNKIHTAVTNAVNSGVAASLPVAFAWSLIVHQMHLGYQERAERRDLLVNQRAQAGFELEFQPSASTPNRRRRNSAGSIVSLEASPYDDFLREQRLDNDIAPVEQIAMLATSRGQVYQVMSEMALCLGTTHEAAFRPAVGARARLVFQDLLKRSAYLIPYQDEPVFSLLAILATGRQYWDVTDALSASSLNQVYTDMLDDETLFTQFTMQAINRFPYEFNPFSVLCRVLAAALITNKDKADVVTGWLWRTPTLTVDWNPAWDRSYELCFEDENTNSFRLTRDVDLFGSASPARPRHLAAEERFIIPEGTLGRFVTDVGRTARLEFEHSALALLGKRLEVKAAEEICDSGMAPLDVDEQAEAVAMLATVLRAESLKSTAKGGDPEAPLKFLKEASRLLPHNKDILTVISDTIDGLVEKELLELDGPQIAVLASCLQFLHAALAVCPGRVWAYMSRCALIAGDARPGRLSRITGSLDMYAERFDLLSSAVKLFAALIDSAACSAVQRRAGSTALVSVRSAVENPWLGTSEKILSRVALAIAQAALDVYESTTTWRFRSELDRSILVRDVVGLMHKLVVHAHTLSSHLTSTLSPAAAHIISSFLTPPPSASSLRFQPLLGTLLVALITPRATLYPGQSRILAERVTSVLAFCTSLLRAADFLGQTHIPLQTHLFQSACLLARLPAANAVYRAPVLELLRALVEVAGRAANGSGEPPSLLGYLGSHAARSFISLVEGIDKPFGRVEHAVVTWRFFAAVIRNRQQWMAGCLLTGRTPREALKGGGEQKIERKVGEGSVLAAAMERLREVKSLDVQEAVAVMDFVVSAQNYWPWTIFAVRKEKEVVDALRGYVRGLKAPGMVMKTDGAAAAAFQARIAAYVAETFAMQLYHMRQMRQAEKFAGELVADLDYFLREGVMVWGYNASLHGNFARNFAKRFPGVEVDDFKRTMWLPRELGKGYYYALEVAEQMLGFDAGWGGVKQSGFRKEMETANLNLSLVEAQVSLFHAWEYLLLELTLSLLPKKENAAFARQVLQVVEQCLEANQRSQPPENIFVVLGHARAGLALTLLQRLADANQLPRDVTHLLALVSSAIHAVENPFGANDLPYFRTLLKILFVVLRAAKQGTAKPGESNVAITQQVLTILDRVVARCFRALAALVHEQQQNATDGTTTAPEDLALITAILQACLSVPGIEQCQVQVLNIMAAHDVFQVAVALFSWADRLLPANPSPASSSTSTSATNPASGDPVYGELALLFLLELSALPALAEHLACDGLLGHLAAARLAGYMRRTNVGPFAENAGAARCYAIWAKCLLPLLLNILAALGSTVAPEVAWVLNQFPNLLQSSVERIEPPGFSRPTLSLASTPPRQKFISLLEISEIHSLALLTRVLAACRAQNARDVPEVTWDGAKVLECVEYWLRGRKVLRERLVPLGPREVEWRGMVATGGVVGVAGDGGEGCENRLEEKAVGLLVGVREVLEGGLEGEGE
Protein: Neurofascin (P97685)
Organism: Rattus norvegicus (Rat)
Function: Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. Isoform 2/isoform 3 may be responsible for mediating and signaling axon-glial interaction during the early stages of myelination.
Subcellular location: Cell membrane; Single-pass type I membrane protein. Note=Isoform 1 colocalizes with ankyrin G at the nodes of Ranvier. Isoform 2/ isoform 3 is a glial component of the paranodal axo-glial junction.
Interaction partners:
- Contactin-associated protein 1
- Contactin-1
- Ankyrin-3
- Ankyrin 1
- Gliomedin
- Syntenin-1
- Ankyrin 2
- Sodium channel regulatory subunit beta-1
- Sodium channel regulatory subunit beta-3
- Receptor-type tyrosine-protein phosphatase zeta
Sequence:
MARQQAPPWVHVALILFLLSLGGAIEIPMDPSIQNELTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTSSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWLVNGDPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDDNNSPITDYVVQFEEDQFQPGVWHDHSKFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPETVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEESPTPPNEATPTAAPPTLPPTTVGTTGLVSSTDATALAATSEATTVPIIPTVVPTTVATTIATTTTTTAAATTTTTTESPPTTTTGTKIHETAPDEQSIWNVTVLPNSKWANITWKHNFRPGTDFVVEYIDSNHTKKTVPVKAQAQPIQLTDLFPGMTYTLRVYSRDNEGISSTVITFMTSTAYTNNQTDIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVRKDKEETEGNESSEATSPVNAIYSLA
Protein: Musculoskeletal embryonic nuclear protein 1 (Q99JI1)
Organism: Mus musculus (Mouse)
Function: May be involved in the development and regeneration of the musculoskeletal system.
Subcellular location: Nucleus {ECO:0000269|PubMed:20130207, ECO:0000269|PubMed:38458566}. Cytoplasm {ECO:0000269|PubMed:38458566}. Secreted, extracellular space {ECO:0000269|PubMed:38458566}. Note=Secreted from smooth muscle cells into the muscle extracellular space. {ECO:0000269|PubMed:38458566}.
Interaction partners:
Sequence:
MSEAGTPEGPIKKKRPPVKEEDLKGARGTLAKNQDIKSKTYQVMRDYEQAGSAAPSVFSRNRTGTETVFEKPKEGPAKSVFG
Protein: Homocysteine S-methyltransferase, putative (EC 2.1.1.10) (Q4GZ92)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
- Cystathionine beta-synthase, putative
- Adenosylhomocysteinase
- S-adenosylmethionine synthase
- S-adenosylmethionine synthase
- S-adenosylmethionine synthase
- Kynurenine aminotransferase, putative
- Homoserine kinase, putative
- cystathionine gamma-synthase
- NADPH--hemoprotein reductase
Sequence:
MKDISCPTGETGSIFEKSKKFQHFFTMDGAVGTLVERCGLDPSKMGSMWSTSALITDEEIVRYVHKSYLDVGADVILTNTYQMHAAGCAQAGVTMNEVVNTAVRVLCDGITPERAAATKEAKVWAQHVMNNKRSEFVNVFAPLFYGPRDDASKCPVLVGGSLGSYGASLGNAQEYRGEYEVNEDIIRDYYVGRFMAFVNHVDEKEAHLKVDFIMIETIPLLNEAIEIFTWLKYQKEDETLRSAPVCLSFISCLREPRPDVTVDDATLNEWWLAAESNIRLIDGNTFEKAFNSLMELQLPQLVGFGTNCCSPLEASVVASAFLKKKKHKVTDPSLALFLYSNSGENFKEGEWHWGGQLPRGSHSPTSSPKETLPFTTLQRLMLCCEADVRTAAFFAYQLLLQRPEADDWLFDIIICGGCCRSTPEDIAMIRSLV
Protein: Missing-in-metastasis, isoform I (A0A0B4K7H4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDLSLERDSSALGSLFQQIINDMKNTSPLWEDFVAKAGKLHTCLRAAIQAIAAYLDAFQKIADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARKGQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAMQSIALVTKEPSVLPQASEELIHDAKASINLYPESPGGGSGSQGGGCSNSLGSRKSSVCSISSMNSSGSSNSPGHHHYPRSLSQFVTPAIRLKPGESSDSGFCSSPALTTQTSNATNQTANVSTWPPHSQDGVDTLPPTADRPHTISTAYEKGHQRPPLTVYTFQNPETIHESGSCLNNGTAAPNGQPLSGQATPATQKSPAASLSRPPLPVRCSSLERPLSAQSNHRQGSGNNLLQRQCPSPIPAHITKELSAAHHAQQQQQQQNQQPQTPPTYVNMSELATMAALKQTNQQQKPSTPPLQQQSSIDSTSSQHSNDSTGSHQLLQQQQQHHQSQQNHHSATATRSHSISSTASSLHSHPSIDSTVACGSLVGQHNHSTSTNTNTTSPSSGSSTPQNHYSPLLTNSPTSTAAGTPSGSSLGPGSGLGFVYQVSSPTPPSSEVLKITEQAAAGQDQGPANSVADETDERSRASVLQKASMFEKAAAAAAVSPPAPMQIASGSPASGGGTRRSEAEQQEMDKSFEDSIQALNNLIGELDSFQREIDEGKVKPPSNIISGSTTSSNNNNTTTSSISSSDNNNLPATSNIEPCAISNQTNSSGCGTDISDTTSDELAGDDMDVRRRDRDRDRDLLGASDSELSRCYVSETSSLTGGLTAGGYENPTFAHFAANANREDAVSLASDSVCLGQPRHAYVDTCSDSGSAVVVIYDHQIPNTPDIEFVKQNSEIVVLRTKDPQPHALQLHEMRELQQLPANLAGSPDSSPDSAGGQAPPTATVAPAKQRLSSFRATSEQQLQLLGRGSPQRGKTPSEQAVQSRPQDQHFPQTQQQDIDGSSPPVELARRQLPPKPTSLSIFNGPVPTAGDRPVVPRKSDFKADLDAKIRRQKQKVKQQLQQQQQQQQQEQQETQQQQQAPQEQQHSPQSPQTRNCNVTNQQAANITASASAFATATASTDPYPNPNHRMPNQNQTATSNHTQCKTPTMALSPSSPRGHLPLSSSSLSSLPLPATTSSPSNARPSMLPASDRPPAHPYVCSNAPANPHHANSISNANAHLKPCITPRPASLSGGAAGGGSTRIGRRSSINQSKPPPPVRRSSSVTPSPNASVGLQQQPQHATLSQQNHQLSSSSEHLPPPPPFMLDAMPQIPSSALKVSETVRALAAMRHQPASPVSLRRMQQQQQQQLQQQQQQQVQQQQPLLQSAHNSPLKEDLTVYYDSYLDLHAYAQALASGQQPGGQQMANQQRFTLQQQHQHLHQPQQPPVYQVDATFRTSSPAAGGGGGGGIYAQPKLVNSMSSFRTSSPSPNGHAHPLPPTQPKANPNLIAQLNARLSGKQQQHQQQQHIEGIYGNQQAPGGESIYMRSGLSMSQPQQQQHFDAAQSPNMRQAHSHQHHQPPQQQHYTCPPPLEDPPPPPIYAAGASATMPKKMARPPTGQNATHSSAYAAASSTATLPKNMMQQQQRLQHQQQYQQPAGMGIGNGNGHLGQRPQLPLPQQKLRAAQQQHLAEQQHQQQQEQQQHHQQHQQHQQRQPPIPSRHSSVQQKIFVSTNPFIQTTAVKFHSPSASPTCGSPVTGSLASIYATTSRGGHHHQQQQAQQQQHYYRDAAGGNSNGGAAYYNHNAHAHSQAHHPNYATSTNIEKTGSIRAKTKAEFLENLNAKLAKQGMSGRAFAVRNLINSKALPDPRICHESLMDQIKRGATLKRNQKINDRSAPKIH
Protein: Hyccin (Q3E983)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
- Phosphatidylinositol 4-kinase alpha 1
- Phosphatidylinositol 4-kinase alpha 2
- Protein NPGR1
- Protein NPGR2
- Protein NPG1
- Uncharacterized protein
- ARM repeat superfamily protein
- Uncharacterized protein
- ARM repeat superfamily protein
Sequence:
MSDSSSSHDSPPSPAITGDSETTVTNNESESNTKCQTAIQSLSTIVTNTNIPSTITILLDDEAVSTAISSLLLRPDSGAGDNNLCRWLYDTFQSAEPSLQLLVLRFVPLIAGLYLSRVPLRQPQAGFEAVLLALYAHETTSRAGQAITVNIPDLSYPSIYHESKGLTRNNNSTCLNIAVISSTLDPHGTVRSTRRARIVGVALELYYSKISKMPRESKLNFCESCEKWAGQNGETEQSSRAVIPTLSDDSWREEENVAIGGRSERDSGRIPLPWELLQPILRILGHCLLGLKMEDRELSEAANKACQSLYLRSLHDINPKAILATGSLLRLREMALDPKNQIDHTELSNDTVLSV
Protein: D-amino-acid transaminase, chloroplastic (EC 2.6.1.21) (EC 4.1.3.38) (Aminodeoxychorismate lyase) (AtADCL) (Branched-chain-amino-acid aminotransferase-like protein 3) (Q8L493)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Amino acid aminotransferase showing activity for D-Asp and D-Ala as amino donors with 2-oxoglutarate as an amino acceptor. Can also use D-Met, D-Tyr, D-Phe, D-Gln, D-Trp and D-Asn as substrates, but no activity with L-Asp, L-Ala, L-Leu, L-Ile or L-Val. Catalyzes also the reverse reaction where an amino group is transferred from D-Glu to pyruvate or oxaloacetate to produce D-Ala or D-Asp, respectively. Also involved in folate biosynthesis, acting as an aminodeoxychorismate lyase converting 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate (PABA).
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:15500462}.
Interaction partners:
- Folate synthesis bifunctional protein
- Folate synthesis bifunctional protein
- Aminodeoxychorismate synthase, chloroplastic
- Dihydrofolate synthetase
- GTP cyclohydrolase 1
- Dihydroneopterin aldolase 2
- Folylpolyglutamate synthase
- Dihydroneopterin aldolase 1
- Folylpolyglutamate synthase
- Folylpolyglutamate synthase
Sequence:
MAGLSLEFTVNTWNLRSLSQVPCPLRHGFRFPRRLTRRRTILMCSDSSSQSWNVPVLSSYEVGERLKLARGGQQFLAMYSSVVDGITTDPAAMVLPLDDHMVHRGHGVFDTALIINGYLYELDQHLDRILRSASMAKIPLPFDRETIKRILIQTVSVSGCRDGSLRYWLSAGPGDFLLSPSQCLKPTLYAIVIKTNFAINPIGVKVVTSSIPIKPPEFATVKSVNYLPNVLSQMEAEAKGAYAGIWVCKDGFIAEGPNMNVAFVVNGGKELVMPRFDNVLSGCTAKRTLTLAEQLVSKGILKTVKVMDVTVEDGKKADEMMLIGSGIPIRPVIQWDEEFIGEGKEGPIAKALLDLLLEDMRSGPPSVRVLVPY
Protein: TFIIH basal transcription factor complex helicase/translocase XPB subunit (EC 5.6.2.4) (DNA 3'-5' helicase/translocase XPB) (Q580W5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: ATP-dependent 3'-5' DNA helicase, component of the general transcription factor IIH (TFIIH) core complex, involved in spliced leader RNA (SL RNA) gene transcription by RNA polymerase II. TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. The ATP-dependent helicase activity of XPB is required for promoter opening and promoter escape (By similarity).
Interaction partners:
- General transcription factor IIH subunit 4
- DNA 5'-3' helicase
- DNA repair and transcription factor protein, putative
- [RNA-polymerase]-subunit kinase
- Telomerase-associated protein, putative
- DNA-repair protein, putative
- DNA repair helicase/translocase XPB-R
- TATA box-binding protein-like 1
- DNA repair protein, putative
- DNA-directed RNA polymerase subunit beta
Sequence:
MILGPGGRIFINHGHPAYPHLMDFLTACCEPVCRTLYVSEYTISPSSLSAATAEGTYSMEMVRNVIRYFRLDEQQQIPVDVERYAALERRVRDSVQDTSLDLPMEVGEAKVSANGDVKAEEGCEEATDELSPLAGQVKKEETKEVAAEPRRRFLSLSKRISAKSEPLVTRAVVNTGALQPLPADLEQMLREEENSSRVRIVLQPCLRPVKRRAVGGDKQHSDEQQCQRAEETKLAYFLTSPDRNHMEHLVSRLQDFLVPVLLHGTRRWVVSDVDRGVEERSTAESGRAKTLRRLFEAPSSASGRSVASKSLTNEGANGDGLGGGVGRRCTRIVYKSQVMDGKMRNVRERLYKELSVRADLFYDYVQDHSLHVCDLELSENVRLRPYQVASLERFRSGNKAHQGVIVLPCGAGKTLTGIGAAATVKKRTIVMCINVMSVLQWQREFIRWTNLSEDQVTVCIADKKQMPGDVFITTYSMLIARRSNVPEMEQSADAKLTAKILASVGEQPWGLLLLDEVHTALAHNFQEVLNKVKYKCVIGLSATLLREDDKIGDLRHLVGPKLYEANWLDLTRAGFLARVECAEIQCPLPKAFLTEYLESQSDGDPFARRGTTRMAHSVVCLNPYKLWCTQALLEFHRNRSPPDKVIIFCDQIDGIQYYAQHLHVPFMDGKTSDMERENLLQYFQHSDNINAIILSRVGDVALDIPCASVVIQISGLGASRRQEAQRLGRILRPKPASLDNVCSYFYTLVSQDTHEISQSYERQSWLRDQGFSYRVLQSDMVLQHFLRTGGKLCCVGPPRWWYECAGPSCDSAVAAKGTYWIPFSQEAALRMQSRFVAGVRGCDLTATVLRDTPRPPELKNMGVEEKWTVCFSDSCAPETFGTVQLVEGNPLLVRRICCGPLAVEHDCLHGGEECLQYAVQQMKVMVAKNSKNRIPLTT
Protein: Mitogen-activated protein kinase 16 (F8J349)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MQPDQRRKSAADVDFFTEYGEGSRYRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLLRHPDIVEIKHILFPPSRREFKDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKYIHTANVFHRDLKPKNILANADCKLKICDFGLARVAFNDTPTAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDLLGTPSAEAIARVRNEKARRYLSSMRKKKPIPLSHKFPNADPLAVLLLERMLAFEPKDRPSAEEALADPYFKGLAKVEREPSAQPVTKMEFEFERRRITKEDVRELIYREILEYHPKMLKEYLEGSEPTGFMYPSAVDHFKKQFAFLEEHYGNGTTAAPLERQHASLPRPCVLYSDNSVQNSTDVTDNLSKCSIKETEKPQPERSFPIPMSRLPPQVPQSIQGAARPGKVVGSVLRYNNCGAVAAGEALEQRRMARNPSVPTQYTATNCSYPRRNPVCKDDEENELQPKPQYMARKVAAAQGGSRSQWY
Protein: Muscarinic acetylcholine receptor M1 (P04761)
Organism: Sus scrofa (Pig)
Function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subcellular location: Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKGRERAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFIVTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
Protein: Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16) (Q9NW64)
Organism: Homo sapiens (Human)
Function: Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
Subcellular location: Nucleus {ECO:0000269|PubMed:17045351, ECO:0000269|PubMed:21122810, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:29301961, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:29361316, ECO:0000269|PubMed:30705154}. Cytoplasm {ECO:0000269|PubMed:21122810}. Note=Nearly exclusively nuclear. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol. {ECO:0000269|PubMed:21122810}.
Interaction partners:
- SNW domain-containing protein 1
- Small nuclear ribonucleoprotein F
- Pre-mRNA-splicing factor SYF2
- Protein BUD31 homolog
- RNA helicase aquarius
- Pre-mRNA-splicing factor SYF1
- Cell division cycle 5-like protein
- Spliceosome-associated protein CWC15 homolog
- Pre-mRNA-processing-splicing factor 8
- U2 small nuclear ribonucleoprotein A'
Sequence:
MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYYTQNMEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP
Protein: Retinoic acid receptor gamma-A (RAR-gamma-A) (zRAR gamma) (Nuclear receptor subfamily 1 group B member 3-A) (RAR-gamma-2) (Q91392)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity). Required for hindbrain development and for the development of pharyngeal arches.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- Retinoic acid receptor RXR-gamma-B
- Arginyl-tRNA synthetase
- Cellular retinoic acid binding protein type II
- Nuclear receptor corepressor 2
- Cytochrome P450 26A1
Sequence:
MFDCMEALGMGPRQLYDVTNRGACMLRKASPFYAGLDPFAWTGTASVRSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCQDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCQINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKDVKDEVIPPESYELSGELEELVNKVSKAHQETFPSLCQLGKYTTNSSSDHRIQLDLGLWDKFSELSTKCIIKIVEFAKRLPGFTTLTIADQITLLKSACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPERVDRLQEPLLEALKIYARRRRPNKPHMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEAFEDQSESTEKKPEPEPPAPPPPALLTMKKEQEDEDDSWATENGSEPSPEEEDDDDEDGEEERGTDSDGEAWGGQEPNADVSRKSHGGRAQ
Protein: Zinc finger protein, putative (Q381I0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAMLRGADRGVTVEMIREAATALMRKVEGGHVDLLPAACMPDAQGDVLSTNVSSGTGLESLSGVYERYLCGGSGHADERCIPREGVDSADGNEWLDLLADISDAEIDAAVANLASERRAQYEEQYRSGNDAGFVLINKGSGCSPSGNVDPTQSGEEVESIRRAGGDCSVHQKADENILYFGGIVELTHSCEWRPDMGGATDGGVYTFDHQKDSAPLEPDFGSNPSTDSTHIAAPVPEITREGLSSSPHIGGDFDSYVRDKVRLQLLVDRVAERAREIATREVLGSVREAVEGRDDRVRRYVKRNEEIRGDLVHLLVLMRQLHRQAIADHAGDPFRVQPWERDESVTSCNACSRSFTHLVRRHHCRRCGLIYCHDCSSFLGKLPDRAGCLESSRNWVRVCEGCYTVCCEHRRYVNSIPPPPPPSCHEREGNSPKDPCLSLPLYCKNGKGTLTDGMPPFYVVLPEESYSPSTTVLSLWANALYKGPHRLFGLAEDGAAALYRISAPKFQELLTSTIGTVKSISGYGAKERWK