wanglab/gogpt-training-data huggingface dataset:
Protein: Glycerol-3-phosphate acyltransferase RAM2 (EC 2.3.1.15) (Protein REQUIRED FOR ARBUSCULAR MYCORRHIZATION 2) (K7PEY4)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Involved in the production of cutin monomers. Esterifies acyl-group from acyl-ACP to the sn-2 position of glycerol-3-phosphate, a step in cutin biosynthesis (Probable). Required for colonization of the root by mycorrhizal fungi, and appropriate hyphopodia and arbuscule formation. Cutin monomers act as plant signals that promote colonization by arbuscular mycorrhizal fungi. This signaling function has been recruited by pathogenic oomycetes to facilitate appressoria formation and their own invasion.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein NODULATION SIGNALING PATHWAY 2
- GRAS family transcription factor
- ABC transporter G family member STR2
- GRAS family transcription factor
- Protein CYCLOPS
- Protein NODULATION SIGNALING PATHWAY 1
- Calcium and calcium/calmodulin-dependent serine/threonine-protein kinase DMI-3
- Protein VAPYRIN
Sequence:
MHPCLVETESVSLLQEEITIITMASSTFPTVNKCTSIGREKHTVVADMDGTLLIGRSSFPYFALIAFEVGGVLRLLIYLLASPIAAILYYFISESAGIQVLVFASMAGMKLSSIESVARAVLPKFYSSDLHPETWRVFSSCGKRCVLTANPRIMVEPFLKEFLGADMVLGTEIASYKGRATGLICKPGILVGDKKAQVLKKTFGDEKPDIGLGDRVTDAPFMALCKEGYIVPAKPKVTTVTSDKLPKPIIFHDGRLVQKPTPLMALLIILWIPIGFPLACLRIAAGSLLPMKFVYCAFKALGVRVIVKGTPPPPVETSKTNHQSGVLFICSHRTLLDPIFLSTALGRAIPAVTYSVSRLSEIISPIKTVRLSRDRATDAAMIKKLLQEGDLAICPEGTTCREPFLLRFSALFAELTDELVPVAMVNRMSMFHGTTARGWKGMDPFYFFMNPSPVYEVTFLNKLPKELTCGSGKTSHEVANYIQRVVASTLSYECTSFTRRDKYRALAGNDGTVVEKTNKANKVMGC
Protein: Tachykinin-related peptide 2 (TKRP-2) (P86595)
Organism: Pyrrhocoris apterus (Sap sucking bug) (Cimex apterus)
Subcellular location: Secreted {ECO:0000269|PubMed:19084564, ECO:0000305}.
Interaction partners:
Sequence:
APASGFFGMR
Protein: Amino acid transporter (D7RVR7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
Interaction partners:
Sequence:
MMPKHVEVRMHESHLEPIEARPLSKWGTICQKMRKNLLLTLTVMGVIMGAVSGMLLRVASPIDDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNPKLKENLGEGLENDEVSSLDAFFDLIRNLFPENLVQACFQQIQTVVKKVEVQPDLDDTNSTMSEYLSNATKPPPIFKDKKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHLSKAELDALDAQHGKTDDIEMMTKTQSYYDDLKNHHENNSNQ
Protein: Nucleoporin 62 (M0QXN5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
Sequence:
MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD
Protein: Germacrene A synthase short form (CiGASsh) (EC 4.2.3.23) (Q8LSC2)
Organism: Cichorium intybus (Chicory)
Function: Involved in sesquiterpene lactone biosynthesis. Produces exclusively (+)-germacrene A.
Interaction partners:
Sequence:
MAAVEANGTFQANTKTTEPVRPLANFPPSVWGDRFLSFSLDTTELEGYAKAMEEPKEEVRKLIVDPTMDSNKKLSLIYSVHRLGLTYLFLQEIEAQLDKLFKEFNLQDYDEFDLYTTSINFQVFRHLGHKLPCDVFNKFKDSSSGTFKESITNDVKGMLGLYESAQLRLRGEPILDEASAFTETQLKSVVNTLEGNLAKQVMQSLRRPFHQGMPMVEARMYFSNYDEECSTHESLPKLAKLHFNYLQLQQKEELRIVSKWWKDMRFQETTPYIRDRVPEIYLWILGLYFEPRYSLARIIATKITLFLVVLDDTYDAYATIEEIRLLTDAINRWDISAMEQIPEYIRPFYKILLDEYAELEKQLAKEGRAKSVIASKEAFQDIARGYLEEAEWTNSGYVASFPEYMKNGLITSAYNVISKSALVGMGEMVGEDALAWYESHPKTLQASELISRLQDDVMTYQFERERGQSATGVDSYIKTYGVTEKEAIDELNKMIENAWKDINEGCLKPREVSMDLLAPILNLARMIDVVYRYDDGFTFPGKTMKEYITLLFVGSSPM
Protein: Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2) (P47866)
Organism: Rattus norvegicus (Rat)
Function: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16766521, ECO:0000269|PubMed:7846062}; Multi-pass membrane protein {ECO:0000269|PubMed:16766521, ECO:0000269|PubMed:7846062}.
Interaction partners:
- Urocortin-2
- Urocortin
- Urocortin 3.
- Corticoliberin
- Corticotropin-releasing factor-binding protein
- Corticotropin-releasing factor receptor 1
- Neuroendocrine secretory protein 55
- Pro-opiomelanocortin
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit gamma
Sequence:
MDAALLLSLLEANCSLALAEELLLDGWGEPPDPEGPYSYCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIINYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNITWFLLQLIDHEVHEGNEVWCRCVTTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIVAWAVGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYCFFNGEVRSALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
Protein: Riboflavin transporter RibU (Riboflavin ECF transporter S component RibU) (Q9X1G6)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Function: Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex. Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (Probable). Expression of the complex plus RibU in E.coli allows riboflavin uptake; uptake does not occur in the absence of RibU or the EcfA1A2T complex.
Subcellular location: Cell inner membrane {ECO:0000305|PubMed:23359690}; Multi-pass membrane protein {ECO:0000305|PubMed:23359690}.
Interaction partners:
- Large ribosomal subunit protein bL21
- Large ribosomal subunit protein bL27
- Hypothetical protein
- Large ribosomal subunit protein uL13
- Small ribosomal subunit protein uS9
- Energy-coupling factor transporter transmembrane protein EcfT
- Biotin transporter BioY
Sequence:
MSSIKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFFLMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKVSSILKLETVEGRSNNG
Protein: RAN GTPase activating protein 1 (Q66H32)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSKLKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLTLKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVLDSFNMAKVLASLSDDEGEDEDEDEEGEDDEDEEDEEEEEEEEEEEEEEEEEPQQRGSGEEPATPSRKILDPNSGRSCCGWVQRSRC
Protein: Arabinose import ATP-binding protein AraG (EC 7.5.2.12) (P0AAF3)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system (Probable).
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01721, ECO:0000269|PubMed:7028715}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01721, ECO:0000269|PubMed:7028715}.
Interaction partners:
- L-arabinose-binding periplasmic protein
- L-arabinose transport system permease protein AraH
- Ribose import permease protein RbsC
- Probable ABC transporter permease protein YphD
- Autoinducer 2 import system permease protein LsrC
- D-allose transport system permease protein AlsC
- Autoinducer 2 import system permease protein LsrD
- Inner membrane ABC transporter permease protein YjfF
- Galactofuranose transporter permease protein YtfT
- Galactose/methyl galactoside import permease protein MglC
Sequence:
MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGAGKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAENIYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALARNAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKDGRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPISLAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMMLCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPGAEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGVAVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA
Protein: SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1) (Q9NR83)
Organism: Homo sapiens (Human)
Function: Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.
Subcellular location: Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus.
Interaction partners:
- Ubiquitin-like protein FUBI
- Solute carrier family 2, facilitated glucose transporter member 4
- Myocyte-specific enhancer factor 2A
- Lck-interacting transmembrane adapter 1
Sequence:
MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPRGDAKKCRKVYGMERRDLWCTACRWKKACQRFLD
Protein: Small ribosomal subunit protein bS6 (30S ribosomal protein S6) [Cleaved into: Small ribosomal subunit protein bS6, fully modified isoform; Small ribosomal subunit protein bS6, non-modified isoform] (P02358)
Organism: Escherichia coli (strain K12)
Function: Binds together with S18 to 16S ribosomal RNA.
Interaction partners:
- Small ribosomal subunit protein uS13
- Elongation factor Tu 1
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein bL9
- Large ribosomal subunit protein uL14
- DNA-directed RNA polymerase subunit alpha
- Replication restart protein PriB
- Large ribosomal subunit protein uL30
Sequence:
MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEEEEEE
Protein: GH01626p (Q8SWY2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVVAPEAMHESFMSDSEEEGGEDNMLSDQPYRYLTVDEMKSLGDDSLPIDVTRDERMDSNRMTQSAEYASGVPPTIGEEVISPHKTQVYGSSPKATVDGVYIANGSGHDEPPHVGRKLSWKSFLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQVNLFKPRKGVAPEKLRKISVNHVPKKKRFSLIW
Protein: Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) (P41565)
Organism: Rattus norvegicus (Rat)
Function: Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- Isocitrate dehydrogenase subunit alpha, mitochondrial
- Isocitrate dehydrogenase subunit beta, mitochondrial
- Aconitate hydratase, mitochondrial
- Isocitrate dehydrogenase, mitochondrial
- Isocitrate dehydrogenase cytoplasmic
- 2-oxoglutarate dehydrogenase complex component E1
- 2-oxoglutarate dehydrogenase-like, mitochondrial
- Cytoplasmic aconitate hydratase
- Dihydrolipoyl dehydrogenase, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
Sequence:
MALKVAIAAGSAAKAIFKPALLCRPWEVLAAHEAPRRSISSQQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHDLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFDSMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSQAIQDIIRHIRIINGRAVEA
Protein: Fragile X messenger ribonucleoprotein 1 homolog A (xFMR1-A) (P51113)
Organism: Xenopus laevis (African clawed frog)
Function: Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs (By similarity). Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q06787}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q06787}. Chromosome, centromere {ECO:0000250|UniProtKB:P35922}. Chromosome {ECO:0000250|UniProtKB:P35922}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q06787}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000250|UniProtKB:Q06787}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q06787}. Perikaryon {ECO:0000250|UniProtKB:Q06787}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q06787}. Cell projection, axon {ECO:0000250|UniProtKB:P35922}. Cell projection, dendrite {ECO:0000250|UniProtKB:P35922}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:P35922}. Synapse, synaptosome {ECO:0000250|UniProtKB:P35922}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q06787}. Cell projection, filopodium tip {ECO:0000250|UniProtKB:P35922}. Synapse {ECO:0000250|UniProtKB:P35922}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:P35922}. Presynaptic cell membrane {ECO:0000250|UniProtKB:P35922}. Cell membrane {ECO:0000250|UniProtKB:P35922}.
Interaction partners:
Sequence:
MEELAVEVRGSNGAFYKAFMKDVHEDSITVTFENNWQQERQIPFHDVRFPPPSGYNKDINERDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKSSFHKVKLDVPEDLRQMCAKDSAHKDFKKAVGAFSVSYDSENYQLVILSVNEVSIKRASMLSDMHFRSLRTKLSLMLRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQEAVKKARTYLEFAENVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENDKNISQEEGIVPFVFVGTKDSITNATVLLDYHLNYLKEVDQLRLERLQIDEQLRHIGASSRPPPNRPDKEKGYLSEDCSGTVRGSRPYSNRGRSRRGTGYASGTNSEASNASETESDHRDELSDWSLAPAEDDRDNYHRRGDGRRRGGTRGQGMRGRGGFKGNDDQPRPDNRQRNSRETKARTSDGSLQIRLDCNNERSVHTKTLQNASVDGSRLRTGKDRVQKKEKTDGVDGPQVVVNGVP
Protein: Protein-lysine N-methyltransferase EFM6 (EC 2.1.1.-) (Elongation factor methyltransferase 6) (P53970)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-390'.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03198, ECO:0000269|PubMed:14562095}.
Interaction partners:
- Protein-lysine N-methyltransferase EFM5
- Protein N-terminal and lysine N-methyltransferase EFM7
- Protein-lysine N-methyltransferase EFM4
- Protein-lysine N-methyltransferase EFM1
- Histidine protein methyltransferase 1
Sequence:
MESIFGGFGDLVVPRPKEHLGQTDLSFGGKLLPALKICEDGGESGCGGKVWIAGELLCEYILEKSVDHLLSKTVNGTKQFKKVLELGSGTGLVGLCVGLLEKNTFHDGTKVYVTDIDKLIPLLKRNIELDEVQYEVLARELWWGEPLSADFSPQEGAMQANNVDLVLAADCVYLEEAFPLLEKTLLDLTHCINPPVILMAYKKRRKADKHFFNKIKRNFDVLEITDFSKFEHYLKERTHLFQLIRK
Protein: Transmembrane and coiled-coil domain-containing protein 4 (Q5TGY1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAMWNRPCQRLPQQPLVAEPTAEGEPHLPTGRELTEANRFAYAALCGISLSQLFPEPEHSSFCTEFMAGLVQWLELSEAVLPTMTAFASGLGGEGADVFVQILLKDPILKDDPTVITQDLLSFSLKDGHYDARARVLVCHMTSLLQVPLEELDVLEEMFLESLKEIKEEESEMAEASRKKKENRRKWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAATIIGSAGAAALGSAAGIAIMTSLFGAAGAGLTGYKMKKRVGAIEEFTFLPLTEGRQLHITIAVTGWLASGKYRTFSAPWAALAHSREQYCLAWEAKYLMELGNALETILSGLANMVAQEALKYTVLSGIVAALTWPASLLSVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGRRPVTLIGFSLGARVIYFCLQEMAQEKDCQGIIEDVILLGAPVEGEAKHWEPFRKVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRVENVDLTSVVSGHLDYAKQMDAILKAVGIRTKPGWDEKGLLLAPGCLPSEEPRQAAAAASSGETPHQVGQTQGPISGDTSKLAMSTDPSQAQVPVGLDQSEGASLPAAASPERPPICSHGMDPNPLGCPDCACKTQGPSTGLD
Protein: Protein delta homolog 1 (DLK-1) (Preadipocyte factor 1) (Pref-1) [Cleaved into: Fetal antigen 1 (FA1)] (O70534)
Organism: Rattus norvegicus (Rat)
Function: May have a role in neuroendocrine differentiation. Inhibits adipocyte differentiation.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein. Cytoplasm {ECO:0000269|PubMed:9645708}.
Interaction partners:
- CD209a molecule
- Insulin-like growth factor 2
- Neurogenic locus notch homolog protein 1
- Scm-like with four mbt domains 2
Sequence:
MIATGALLRVLLLLLAFGHSTYGAECDPACDPQHGFCEADNVCRCEPGWEGPLCEKCVTSPGCVNGLCEEPWQCVCKEGWDGKFCEIDIRACTSTPCANNGTCVDLEKGQYECSCTPGFSGKDCQHKAGPCVINGSPCQHGGACVDDEGRASHASCLCPPGFSGNFCEIVTNSCTPNPCENDGVCTDIGGDFRCRCPAGFVDKTCSRPVSNCASGPCLNGGTCLQHTQVSFECLCKPPFMGPTCAKKRGTSPVQVTHLPSGYGLTYRLTPGVHELPVQQPEHHILKVSMKELNKSAPLLTEGQAICFTILGVLTSLVVLGTVAIVFLNKCEAWVSNLRYNHMLRKKKNLLLQYNSGEELAVNIIFPEKIDMTTFNKEAGDEDI
Protein: Alhambra, isoform L (A0A0B4KFD2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKEMVGGCCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSRVRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKTIPPYKPIQHDTSSDSCSSPEKEIDSTMNSATTSATIIKITSSSGSAGGSSNVLNASSSAGISAGSSSGSGVSSSAKQRKSNASSKSSSSSSSSSSSSTGGAPNPSSSSVHSGSASNMTGGGSVLPGSSNIGNISNSLNNNLPGGSSSTSSAGNVPGGSGGIISASSGGATQSTSSQSSTAPGTTKSSASSSSSSSNSYKEKHSKSLSKSTSSKDKDGKDSSTNSANNNFTNSSASSTSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSSINTQPSSSTSTATAGSGGTGTHVSSSAASGLNSAPSTTNEHSNHAHTLSTNGTGAGSAAGKLQSVSNLSNSSSGFGSDLRSVSTSSSSTVNDSTGGFGSNSNSERENLSGAGSSASNMPGTIAPGTGGVSSSAATNLSTNKGGSSSSTANSLTSTSTSSGSSSNSSSKKRKADSAKSTSSISTSGSALEDNNRWGTRNAKKSLISRYDIKDVQVALTPLTDFEKEIEKSSKRQRTELSPPTHQTSATAEVNAPLASSTSASIAVTASATAASAPPATGTTTLGSSISGNAGSTSSGNSSGVSATGGAQSAVGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQASTASSSSAPSLYVSVPLSTANVPGINLPTSSTSSSTTSESHSASSRSSGAQSQHQQQLSNALVGPPMGGSAGAFHGGTTSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISASGFPLPSGNLTATTTESGNLKISYEKQTTRVQQLQEQEAPPARRSRTLDLSTASASSSSPSAVPATTSPLVVLSNQLPLNSVAASSSTGGLKFTYESQTQMDVPMMPVSAIKDSPPSSPGSEIGSAMHSATTAPGSLTGASTAATAQPGNVRKRGRKAKDATIAAAAAAAAAAAALSNSQQDLKDVRILQNGASNTPGNPAGSTPTPPATPASSNAVSSASSIITHTAAHMLGNQINPNSSVAQKLSEQLHMEVQDHSIYTPDSMNSQYAGVPFPGKQRNSTAVPSNATPAQNPLQSMFSGGGMNGNMPIPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLNCLHQLQSENLRLEEHVTSLIARRDHLLAVNARLQIPLSTIASNTKAEAHGK
Protein: Reduced meiotic recombination protein 1 (P53060)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for normal levels of gene conversion events during meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Ribosome assembly protein 4
- Ribosome biogenesis protein YTM1
Sequence:
MSEEEAHKTVEVDDVGVQLDEGDEEDLLEYDDELVEEQPSDARIRNVAETLMKSELPKVTVEYKDTTFLLFTSDDKNESNNPIICENAALYQRPMGEFMESIRKFMGNRFGRLAFATKELVLQLKSLDLTLFEDNVYNNHISFSDVYTIFKILKERSESNFETDIPTHLAIELSTRPRFVSRYNALVELTESSATLKNIKPFSNDETHPLIVDDNDQYTHQNTSEVIVMDIDDDVGEDSED
Protein: Tenascin-R (Q7T3T6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MWGCTMAIQGSVVSLALLFFGIQAVPSPTSKLVRTTRVRRQVPEGGDPADNQMQPMVFNHVYNINVPVESLCSVDLDAVTGPETNKTASGSDKMPTEYTEETVDSDSQVTFTHRINIPKQACACPSATTIEQLASRIEMLEREVSLLRTQCSSSCCGESSVMGRLDFVPQCGHGTFSMEVCGCVCEEGWIGKNCTEPRCPDDCSGQGICIEGDCVCDRNFGGENCSEPRCPSDCSDRGLCIDGECVCEEAFAGEDCSLGRCLNDCSDQGACVNGSCQCRSGFLGEDCSLIFCANNCSQRGVCKEGFCVCQEGYTGDDCTSVLPPMNLRVRGVSENTIDLQWEGPAILTDYLITYEPTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAVIDNIISSPMNTLVSTYLSNPDGLLFKSIMETSVEVQWQPLDYLFDGWEISFIPKDNDGGMTAQLPSTITSFHQTGLKPGEEYTVNLVALKDQGRSLPVTATVTTLIDGPIQLIVRDISDTVAFVEWSPPKAKVDQIILRYGLVGVEGPKTTFRLQPTLSQYSLQVLRPGSTYEVSVSGVRNGTESGVISTEFTTEIDAPKNLRVLSKTSISLELEWDNSEADVEGYSVVYSTLAGDQYDKVIVPRNDGPSTKTTLNELMPGTEYGIGISAVLGANQSTPATMNARTGLDVPLDLTVTASTDNTITLLWGTVQGPIDHYRVTYTSSSGVTTELTVPKDVTTTTLTSLQPGTEYTITVAAQRGRQQSTAATIDAFTGFRPITQLFFSEVSSDSLTVAWSSPAPPADAFILNYSAQDSSEDSEIALDGSKTRITLTGLMPSRRYTATLVTMHGNVTSKPVVGSVNTGMDPPRDITVLYVTEESVTITWIQPLALLDYYRMSYQSSKGRMDSVVIDSDINNYTLTSLHPATEYEIKLNAVRGSQESKVITTTVFTAIDMPAELTALNVTPQGALLRWNPPASSVDNYVLTVTRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYATKGPLTSGTVISNFVTPMDAPQNLTASEINHRSALISWQPPIADIDNYMLTYKAADGSRKELILDAEDTWIRLEGLAETTEYTVRLQVARGLETSVIVSTSFTTGNRLFPTPQNCAQHLLNGETLGGIYTIYVNRDLSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGSLEDEFWLGLDNIHKIAAQGRYELRIDMKDGQESVYANYDRFSIGDSKSLYKLRIGEYSGTAGDSLSYHQSRPFSTKDKDNDIAVTNCALSYKGAWWYKNCHRANLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRPFNYRSISGKRRRSAH
Protein: T cell receptor gamma, constant 1 (A0A075B5Z0)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
XKRLDADISPKPTIFLPSVAETNLHKTGTYLCLLEKFFPDVIRVYWKEKDGNTILDSQEGDTLKTNDTYMKFSWLTVPERAMGKEHRCIVKHENNKGGADQEIFFPSIKKVAVSTKPTTCWQDKNDVLQLQFTITSAYYTYLLLLLKSVIYLAIISFSLLRRTSVCGNEKKS
Protein: Fad1, flavin adenine dinucleotide synthetase, homolog (Yeast), isoform CRA_e (Flavin adenine dinucleotide synthetase 1) (Q5T196)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGWDLGTRLFQRQEQRSRLSRIWLEKTRVFLEGSTRTPALPHCLFWLLQVPSTQDPLFPGYGPQCPVDLAGPPCLRPLFGGLGGYWRALQRGREGRTMTSRASELSPGRSVTAGIIIVGDEILKGHTQDTNTFFLCRTLRSLGVQVCRVSVVPDEVATIAAEVTSFSNRFTHVLTAGGIGPTHDDVTFEAVAQAFGDELKPHPKLEAATKALGGEGWEKLSLVPSSARLHYGTDPCTGQPFRFPLVSVRNVYLFPGIPELLRRVLEGMKGLFQNPAVQFHSKELYVAADEASIAPILAEAQAHFGRRLGLGSYPDWGSNYYQVKLTLDSEEEGPLEECLAYLTARLPQGSLVPYMPNAVEQASEAVYKLAESGSSLGKKVAGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAVQRKLPDVPNPLQILYIRSISPFPELEQFLQDTIKRY
Protein: Tyrosine recombinase XerS (A2RKP9)
Organism: Lactococcus lactis subsp. cremoris (strain MG1363)
Function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. Binds an atypical recombination dif site (difSL). Binds preferentially to the left arm and cooperatively to the right arm of difSL.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01816, ECO:0000305}.
Interaction partners:
- Integrase-recombinase
- DNA translocase FtsK
- Protein RecA
Sequence:
MKREQLIQNIEKLKHVMPPYVLEYYQSKLTIPYSLNTLYEYLKEYERFFSWLVDSGVADVDKITDVSLSVLENLTKRDLESFILYLRERPRLNTHSTRYGVSQTTINRTLSALSSLYKYLTEEVENEDGEPYFYRNVMKKVQTKKKSETLASRAENIKGKLFLGDETQGFLDYIDSEYEKTLSNRARSSFFKNKERDLAIIALILASGIRLSEAVNVDLRDLNLNTMIVEVTRKGGKRDAVPFAPFAKTYFERYLEVRSQRYKTTAKDTAFFVTLYRDIASRIDPSSVEKLVAKYSQAFKVRVTPHKLRHTLATRLYAQTNSQVLVSNQLGHASTQVTDLYTHIINEEQKNALDSL