wanglab/gogpt-training-data huggingface dataset:
Protein: Lipocalin-1 (Tear lipocalin) (Tlc) (Tear prealbumin) (TP) (von Ebner gland protein) (VEG protein) (P31025)
Organism: Homo sapiens (Human)
Function: Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
Subcellular location: Secreted.
Interaction partners:
- Protein LMBR1L
- Lactotransferrin
- Apolipoprotein D
- Cystatin-S
- Extracellular glycoprotein lacritin
- Neutrophil gelatinase-associated lipocalin
- Glycodelin
- Protein Wnt-8b
- Complement component C8 gamma chain
- Lysozyme-like protein 1
Sequence:
MKPLLLAVSLGLIAALQAHHLLASDEEIQDVSGTWYLKAMTVDREFPEMNLESVTPMTLTTLEGGNLEAKVTMLISGRCQEVKAVLEKTDEPGKYTADGGKHVAYIIRSHVKDHYIFYCEGELHGKPVRGVKLVGRDPKNNLEALEDFEKAAGARGLSTESILIPRQSETCSPGSD
Protein: Calcium channel, voltage-dependent, T type, alpha 1G subunit (Q5SUG2)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MDEEEDGAGAEESGQPRSFTQLNDLSGAGGRQGPGSTEKDPGSADSEAEGLPYPALAPVVFFYLSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLPENFSLPLSVDLEPYYQTENEDESPFICSQPRENGMRSCRSVPTLRGEGGGGPPCGLDYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNASTLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAVGVRAGLLSSPVARGGQEPQPSGSCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRVPRASPEIQDRDANGSRWLMLPPPSTPTPSGGPPRGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPEMLKDKALVEVAPSPGPPTLTSFNIPPGPFSSMHKLLETQSTGACHSSCKISSPCSKADSGACGPDSCPYCARTGAGEPESADHEMPDSDSEAVYEFTQDAQHSDLRDPHRRRRPSLGPDAEPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEGDATKSESEPDFFSPSVDGDGDRKKRLALVALGEHSELRKSLLPPLIIHTAATPMSLPKSSSTGVGEALGSGSRRTSSSGSAEPGTAHHEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQDEEESSEEDRASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRSSASEHQDCNGKSASGRLARTLRADDPPLDGDDGDDEGNLSKGERLRAWVRARLPACCRERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVCQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLKRLEKKRRSKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGVNSPDSPKPGAPHTTAHIGAASSGFSLEHPTMVPHTEEGPVPLGPDLLTVRKSGVSRTHSLPNDSYMCRNGSTAERSLGHRGWGLPKAQSGSILSVHSQPADTSCILQLPKDAHYLLQPHGAPTWGAIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLSEEEPLSPRDLKKCYSVEAQSCRRRPGSWLDEQRRHSIAVSCLDSGSQPRLCPSPSSLGGQPLGGPGSRPKKKLSPPSISIDPPESQGPRPPCSPGVCLRRRAPASDSKDPSASSPLDSTAASPSPKKDALSLSGLSSDPTDLDP
Protein: WASH complex subunit 5 (WASH complex subunit strumpellin) (E7EQI7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLLVIDQKIEGEVRERMLVSYYRYSAARSSADSNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSAYPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNLVDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIPKLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQFEFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREISKQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINIKEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRINQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDKLRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAFALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINYNVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHIDQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIILRDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQIANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAAGIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGLLTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPRRVAEAHVPNFIFDEFRTVL
Protein: Ig gamma-2A chain C region, A allele (Immunoglobulin heavy chain gamma polypeptide) (P01863)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
AKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK
Protein: CKLF-like MARVEL transmembrane domain-containing protein 2A (Chemokine-like factor superfamily member 2A) (Q9DAR1)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MAAPIKFPFRPRGGQPREDTTPKRGLRRYLLELKESNKEFWLSGHAVFKLLSLGCMISALDYFETMLPHPVLILLICMEAAICIFFIFLNTLAINRYIPFVFWPMADIFNSLFSCVFLGGGIYFAFKARRLLPKPYLTAMILMGAAAICSFIDMLLQFQHFRGLRLRKW
Protein: Exosome complex component RRP43 (Ribosomal RNA-processing protein 43) (P25359)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. RRP43 is part of the hexameric ring of RNase PH domain-containing subunits proposed to form a central channel which threads RNA substrates for degradation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Exosome complex component CSL4
- Exosome complex exonuclease RRP6
- Exosome complex component RRP4
- Exosome complex component RRP42
- Exosome complex exonuclease DIS3
- Superkiller protein 7
- ATP-dependent RNA helicase DOB1
- Exosome complex component RRP40
- Exosome complex component RRP46
- Exosome complex component MTR3
Sequence:
MAESTTLETIEIHPITFPPEVLARISPELSLQRHLSLGIRPCLRKYEEFRDVAIENNTLSRYADAGNIDTKNNILGSNVLKSGKTIVITSITGGIIEETSAAIKDLDDFGEEELFEVTKEEDIIANYASVYPVVEVERGRVGACTDEEMTISQKLHDSILHSRILPKKALKVKAGVRSANEDGTFSVLYPDELEDDTLNETNLKMKRKWSYVLYAKIVVLSRTGPVFDLCWNSLMYALQSVKLPRAFIDERASDLRMTIRTRGRSATIRETYEIICDQTKSVPLMINAKNIAFASNYGIVELDPECQLQNSDNSEEEEVDIDMDKLNTVLIADLDTEAEETSIHSTISILAAPSGNYKQLTLVGGGAKITPEMIKRSLLLSRVRADDLSTRFNI
Protein: T. brucei spp.-specific protein (Q583Y2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTTQTGGKNHPPVFFFRLPVRLRLLPWSNDDMNHSHWVTTGRNLHLHTQRCLLTAVMHENYNTNQKKMTGIARTCSSACRHGSNNEKKKHVHPLTFFLFTTNSSPCFRHLRTARRHACSPERTIYWLEYERISDLPIEEQEKRGATTFVAYTLF
Protein: Cell surface glycoprotein CD200 receptor 3 (CD200 cell surface glycoprotein receptor-like 3) (CD200 receptor-like 3) (CD200 cell surface glycoprotein receptor-like b) (CD200RLb) (Cell surface glycoprotein OX2 receptor 3) (Q5UKY4)
Organism: Mus musculus (Mouse)
Function: According to PubMed:15187158 isoform 4 is a receptor for the CD200 cell surface glycoprotein. According to PubMed:16081818 isoform 4 is not a receptor for the CD200/OX2 cell surface glycoprotein. Isoform 1, isoform 2 and isoform 3 are involved in the recruitment or surface expression of the TYROBP receptor. Isoform 6, isoform 7 and isoform 8 are not involved in the recruitment or surface expression of the TYROBP receptor.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Mast cell protease 8
- TYRO protein tyrosine kinase-binding protein
Sequence:
MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSVFCFISHLTDNWILSMEQNRGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFSSRDLVFMKERRSKRSVWQREALG
Protein: Ankyrin repeat and LEM domain-containing protein 2 homolog (LEM domain-containing protein 4-like) (H2KZB2)
Organism: Caenorhabditis elegans
Function: Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of baf-1 during mitotic exit. Coordinates the control of baf-1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of baf-1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex.
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:22770216}; Single-pass membrane protein {ECO:0000269|PubMed:22770216}.
Interaction partners:
- Serine/threonine-protein kinase VRK1
- Barrier-to-autointegration factor 1
- Ankyrin repeat and LEM domain-containing protein 1 homolog
- Probable serine/threonine-protein phosphatase PP2A regulatory subunit
- Protein mel-28
Sequence:
MGRKSAILAVILAIIYFRSNFSKMSNTPVQETEGPVYVAYSMEDMLKSPRDLYKSVKEVAKFVNSAEGKSMSARFKKFGTPREAMDFLAYGDAPTTPKTVPPVAPTEPNSPFSGVNRIQMNEFKKYVEKGDMENFLRLVDSNPRFLVNTGGDVASIVMEGFRYNALHIAAKAGQTEIIAKILELIQNIDFLIRLYGTGADDVTLRKINILDSYLNTPDKGNSDTPLHFASKFGKIGVVRVLTENSATDRTLLNKSGKSALDCAGERYTGEDKDMVQRDIHLAIEGFYVFLHRNPTTGSTQLTVSQKPPATYSTSPTTATVTVSAQAGPFFTEREARDFAKSWQTAGKELKRTDFDKGWERVGRVLAEQSEAMWRETWHFLGSMELLDLGSEQGLGVLEAFLREKRRGNLRNSEISEISTKKSIFRRGIHARKLDFGILDGEKSAEISENLTPDGSDSADDEDDDDIFYDTFSEIPAAAEKSINDPDDTLGSLTDRFAAISIFSPLPPPPPPQWSNSPNFDYSEGEDSFATPPTTPPPTFVADDEPCKIDNDLFEVLAQISSELISKFPLTQDYVQKLGKLTAHDRSTWRPIDSPARCDSRRKI
Protein: Beta-defensin 1 (BD-1) (Defensin, beta 1) (cBD-1) (P83943)
Organism: Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera)
Function: Has antibacterial activity against Gram-positive bacterium S.pneumoniae Serotype 14. Is also active against Gram-negative bacteria M.catarrhalis 1857, and non-typeable H.influenzae strains 86-028NP and 1128. Has antifungal activity against C.albicans. May have a role in maintaining sterility in the middle ear. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P60022}. Membrane {ECO:0000250|UniProtKB:P60022}. Note=Associates with tumor cell membrane-derived microvesicles. {ECO:0000250|UniProtKB:P60022}.
Interaction partners:
Sequence:
MRIHYLLFAVLFLFLMPVPGEGGIINTIQRYFCRVRGGRCAALTCLPRETQIGRCSVKGRKCCRTRK
Protein: 40S ribosomal protein S27 (Q4VBV2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- FAU ubiquitin-like and ribosomal protein S30 fusion b
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein eS25
- Ribosomal protein S10
- Ribosomal protein S3
- Small ribosomal subunit protein eS7
- 40S ribosomal protein S15
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS4
Sequence:
MPLAKDLLHPTPEEERRRHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH
Protein: DNA repair protein RAD51 homolog (Q384K0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364139}.
Interaction partners:
- BRCA2 OB1 domain-containing protein
- DNA repair protein, putative
- DNA 3'-5' helicase
- Protein kinase, putative
- DNA 3'-5' helicase
- Replication protein A subunit
- Exonuclease, putative
- Endo/exonuclease Mre11
- Crossover junction endonuclease MUS81
- DNA repair protein RAD51 homolog 3
Sequence:
MNTRTKNKKRTKEVIEDEVHDIDDTAFDDAAVDAVNDNTQEMQQQVGDAAGGPSFRVLQIMENYGVASADIKKLMECGFLTVESVAYAPKKSILAVKGISEAKAEKIMAECCRLTPMGFTRATVFQEQRKETIMVTTGSREVDKLLGGGIEVGSITELFGEFRTGKTQLCHTLCVTCQLPLSQGGGEGMALYIDTEGTFRPERLVAVAERYSLDPEAVLENVACARAYNTDHQQQLLLQASATMAEHRVAIIVVDSATALYRTDYNGRGELAARQMHLGKFLRSLRNLANEYNVAVVVTNQVVANVDGAAPTFQADSKKPIGGHIMAHASTTRLSLRKGRGEQRIIKVYDSPCLAESEAIFGIYENGVGDVRD
Protein: Phosphoglycerate kinase (EC 2.7.2.3) (P0A799)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm.
Interaction partners:
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase A
- Enolase
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
- 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
- D-erythrose-4-phosphate dehydrogenase
- Fructose-bisphosphate aldolase class 2
- Glucose-6-phosphate isomerase
- Pyruvate kinase II
- Pyruvate kinase I
Sequence:
MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
Protein: H(+)-transporting two-sector ATPase (EC 7.1.2.2) (Mitochondrial protein YMF19) (Q8HCQ9)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004304}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004304}.
Interaction partners:
- ATP synthase subunit a
- ATP synthase subunit alpha
- ATP synthase subunit alpha, chloroplastic
- F-ATPase protein 6
- ATP synthase subunit a, chloroplastic
- Os02g0750100 protein
- F-ATPase gamma subunit
- ATP synthase subunit 9, mitochondrial
- ATP synthase subunit c, chloroplastic
- ATP synthase epsilon chain, chloroplastic
Sequence:
MPQLDKLTYFSQFFWLCLFFFSFYILLLNNNNGILGISRILKLRNQLLSHRGNKIRFKDPKNLEDILRKGFSTGLSYMYSSLSEVSQWCKTVDYLGKRRKITLISDFGEISGSRGMERQILYLISKSSYNTSSSRITCWKKIMLTHVLHGQGSII
Protein: Calmodulin (J9VTH9)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Interaction partners:
Sequence:
MAEQLTKEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTQAELEDMINEVDADGNNSIDFAEFMTLMARKMHDTDSEEEIREAFKVFDKNNDGHISAAELKHVMTNLGEKLTDAEISEMIREADKDGDGMIDYNEFVTMMVAK
Protein: A-kinase anchoring protein 9 (A0A2R8Y590)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
Sequence:
MDSYSTYLATVKVSGSWLEEQDEDIYEVESRVPLPHPFPLCEHLDENNSVIVNTSIFHFIHKRNGHILKLISKISLPTPPYSLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREICSSDSGSDWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSGSTTQFHAGMRR
Protein: Deoxyribonuclease TATDN1 (G5EG18)
Organism: Caenorhabditis elegans
Interaction partners:
- Exosome complex component RRP46 homolog
- Putative steroid dehydrogenase 4
- 3'-5' exonuclease crn-4
- Small, acid-soluble spore protein gamma-type
- Endonuclease G, mitochondrial
- Flap endonuclease 1
Sequence:
MALYELVDIGANLGHPSYQKDLNDVLDRAKQAGLSKIMVTGTSEKISHECADLVEKYPGFLYFTAGVHPHDAKDWNDGTLEALKKLQENPSCVAVGECGLDFNRNFSPQDVQKEVFAKQVDMAVKLQKPLFIHEREAHEDMVKILTAAGPSLPPAVIHCFTGTVVEAKKYLEMGFYIGLTGFLWKDRSDNGVQAGLRSGEIPIEKLVLETDAPYMYPKINDKKIPKEIKSLITPETEALHNFSSFNRNEPCSLAAVCELVAAFAGRDPKEVAKITTENAKKVYKLE
Protein: Ascaphin-1 (P0CJ25)
Organism: Ascaphus truei (Coastal tailed frog)
Function: Antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. Has a very week hemolytic activity.
Subcellular location: Secreted.
Interaction partners:
Sequence:
GFRDVLKGAAKAFVKTVAGHIAN
Protein: Dedicator of cytokinesis 4 (C9J637)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKMHSTERIPLFGPYPSLLKKIERETWRESGVSLIATVTRLMERLLDYRDCMKMGEVDGKKIGCTVSLLNFYKTELNKEEMYIRYIHKLYDLHLKAQNFTEAAYTLLLYDELLEWSDRPLREFLTYPMQTEWQRKEHLHLTIIQNFDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMDQQRLEPEFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDETIFQAEAQYLQIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMKSSLGIQEFSACMQASPVHFPNGSPRVCRNSAPASVSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQPSPSTSSLSSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLSPRERPCSAIYPTPVEPSQRMLFNHIGDGALPRSDPNLSAPEKAVNPTPSSWSLDSGKEAKNMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAGRSPLKGSVQSFTPSPVEYHSPGLISNSPVLSGSYSSGISSLSRCSTSETSGFENQVNEQSAPLPVPVPVPVPSYGGEEPVRKESKTPPPYSVYERTLRRPVPLPHSLSIPVTSEPPALPPKPLAARSSHLENGARRTDPGPRPRPLPRKVSQL
Protein: Small ubiquitin protein, putative (Q57Z72)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- SUMO-conjugating enzyme UBC9
- SUMO1/Ulp2, putative
- Ubiquitin-activating enzyme E1, putative
- Ubiquitin activating enzyme, putative
- Proliferating cell nuclear antigen
- Leucine-rich repeat protein
- DNA topoisomerase I
- DNA-repair protein, putative
- Ubiquitin, putative
- Polyubiquitin, putative
Sequence:
MDEPTHNSNNGGEPSNNGGEGAEGTCKEETALVAVKVVNADGAEMFFRIKSRTALKKLIDTYCKKQGISRNSVRFLFDGTPIDETKTPEELGMEDDDVIDAMVEQTGGCLWCMA
Protein: Cleavage factor two protein 2 (O74740)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. May be involved in poly(A)-site recognition. May be involved in the association of the CPF, CPFIA and RNA polymerase II complexes (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Protein cft1
- Polyadenylation factor subunit 2
- Uncharacterized RING finger protein P8B7.15c
- RNA polymerase II subunit A C-terminal domain phosphatase ssu72
- Endoribonuclease ysh1
- Poly
- mRNA cleavage and polyadenylation specificity factor complex subunit pta1
- Pre-mRNA polyadenylation factor fip1
- mRNA 3'-end-processing protein yth1
- Uncharacterized WD repeat-containing protein C824.04
Sequence:
MLNYQCLETDSYCGTSHIELDGIHIYIDPGSDDSLKHPEVPEQPDLILLSHSDLAHIGGLVYAYYKYDWKNAYIYATLPTINMGRMTMLDAIKSNYISDMSKADVDAVFDSIIPLRYQQPTLLLGKCSGLTITAYNAGHTLGGTLWSLIKESESVLYAVDWNHSKDKHLNGAALYSNGHILEALNRPNTLITDANNSLVSIPSRKKRDEAFIESVMSSLLKGGTVLLPVDAASRVLELCCILDNHWSASQPPLPFPILFLSPTSTKTIDYAKSMIEWMGDNIVRDFGINENLLEFRNINTITDFSQISHIGPGPKVILATALTLECGFSQRILLDLMSENSNDLILFTQRSRCPQNSLANQFIRYWERASKKKRDIPHPVGLYAEQAVKIKTKEPLEGEELRSYQELEFSKRNKDAEDTALEFRNRTILDEDLSSSSSSEDDDLDLNTEVPHVALGSSAFLMGKSFDLNLRDPAVQALHTKYKMFPYIEKRRRIDEYGEIIKHQDFSMINEPANTLELENDSDDNALSNSNGKRKWSEINDGLQQKKEEEDEDEVPSKIITDEKTIRVSCQVQFIDIEGLHDGRSLKTIIPQVNPRRLVLIHASTEEKEDMKKTCASLSAFTKDVYIPNYGEIINVSIDVNAFSLKLADDLIKNLIWTKVGNCEVSHMLAKVEISKPSEEEDKKEEVEKKDGDKERNEEKKEEKETLPVLNALTLRSDLARAPRAAPLLVGNIRLAYLRKALLDQGISAELKGEGVLLCGGAVAVRKLSGGKISVEGSLSNRFFEIRKLVYDALAVV
Protein: ATPase, putative (Q387F4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- MPN domain-containing protein
- Ubiquitin fusion degradation protein, putative
- Ubiquitin thioesterase OTU
- UBX domain-containing protein
- UBX domain-containing protein
- Ubiquitin fusion degradation protein 2, putative
- Guanine nucleotide-binding protein subunit beta-like protein
- Polyubiquitin, putative
Sequence:
MIRVPSRWPCSSSPVALVQVNDDFVAICGVVSSDEELASWELDCSITLNRQVAERVTAQDFSPAGTHEVCFIGPSKQTKRRFVEVPVHPGGGGDTLRVLTPLSTYEAKTVLLEGPRVSTPGFMERLFASLVGRYVVVDCDVMTQEGLQFRVKDAELKRGYRGLALVGSTARVKLNQRSAKYFWPSDVLVGLEEQAQELRTVMQAMLQSPGRWLGVSLHDSSGCEALTVVRKCVADANGTLVWWSPSSVYGQGGDYCASRLIVLCIPDMDEVFPSSDSSLAGLTVRLLRGSIDSLLNSGSSEKPALVLVGITKNEIIGVANSLFAAKISFEFPDVDKRAVLLAHVRGGDRMDHMSEAHTLVGLSRSEVLDAARRQPRSRGPLNKVLRWSDIGGLDDVKDRLHRALILPQLEPGLFARFGLTPPRGILLYGPPGCAKTSLVKALCSEGCFSFIYLDFAGLISAYVGESERILRDAFHRAARQAPCIVFFDEVDAIGGKRAMNSRDGDQARLLSTLLTEMDGFSSSNGVCFVGATNTPHQIDAALLRPGRFDYLVYVPLPPLGDRRRVLSLVLGNTTADLDKLARVTEGFSGADLPALATSVLLELLDGTDEGSASECLNDSEALTQLLVSRAGEFHKTSYDVAALERFNRDCSSDSGAV
Protein: Probable 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (ACCD) (EC 3.5.99.7) (Q9URX3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.
Interaction partners:
- Putative formamidase C869.04
- Probable L-lactate dehydrogenase
- AB hydrolase superfamily protein B1A11.02
- Protein sum2
- Putative serine acetyltransferase
Sequence:
MGLEQFKKYPLTFGPTPITSMKRLSKTLGGKVEIFAKREDCNSGLAFGGNKIRKLEYLIPEAIDGGYDTLVSIGGIQSNQTRQVAAVAAHLGLDCVLIQEDWVDYKDTMYDRVGNIELSRIVNADVRLDSSKFDIGIRPSFKNALEELTKKGKKPFPIPAGCSEHPYGGLGFVGCVEEIYEQEKQLGFKFDKIVVCTVTGSSFAGIIVGMALTGRQKDVIGIDASATPEKTKAQVLRIAQNTAKLIGLEKELTESDVNIDTRFAHPAYGIPNEGTIEAIKLCGATEGVLTDPVYEGKSMQGLIHLVRNNEIAEGSKVLYIHLGGAPALSAYSAYFKNT