wanglab/gogpt-training-data huggingface dataset:
Protein: Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) (D3J0E7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323}.
Interaction partners:
Sequence:
MFGSLCARKLARRSRSALIAALTVLLVQTLIVWNFSSLDTGEDRKDNGREKRDRIGINKAYSEYPKSGFQKRQHQPPLGKASNRHKQQPDGYYSHRPKEKVRVDSNNENSVPKDFENIDNSNFGARSQTQRHAPGKHKQGLLEKAHAQQSQSKNSNEVIQYAQNKAGLNQTHTDLHQRANPTLRPQQSQQHRHHFQRPKRSITPTADIKYDQPPKCEISGKEAISALSRAKTKECRQQIVEVYCRHKEHQLMPEKVTRYCPVEGKVNMNVQWEEDSMETVPAVPVRIAFMLVVHGRATRQVQRLFKAIYHTSHFYYIHVDQRSNYLHRQMVALAHQYPNVRVTSWRMSTIWGGASLLTMYLQSMKDLLAMRDWSWDFFINLSAADYPIRTNDQLVAFLSKYRNMNFIKSHGRDNARFIRKQGLDRLFFECDTHMWRLGDRKIPEGISVDGGSDWFLLNRMFVEYVINTQDDLVTNMKRFYAYTLLPAESFFHTVLENSPHCESMVDNNLRITNWNRKLGCKCQYKHIVDWCGCSPNDFKPSDLPRFQQTTRPTFFARKFEASVNQEIVNQLDVFLFGSLPQGTPGLKAYWENVFDEADGIHSLSDAHLTHYHAFARLGLARTANSLQGDPNDNSCRYFAMGHPVSVHIYFLSDEFQGYLVRHHATNLATSKLETLETWVMPKQFYKFTNPPKTFTRLQFAEIGTDWDAKERIFRNFGNMMGPMDEPVGMQKWGKGSNVTVTVVWIDPTNVIAATYDILIDASAEFTHYRPPLNLPLRPGMWTVRVLHHWSPVAETRFLITPLTHHKHLPIRHEDALKMHNGPAKNSYMEQSFHGLNPILNIPVHLGQVEAAEHNAGLTGSELERWVDSLVGDVWSAVDVCSTGPSGCPVMQTCRETVWSSLSPDPKSQLGPPKNNGRIR
Protein: Expressed protein (Sugar phosphate exchanger, putative (DUF506)) (Q9SIU5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Antigenic heat-stable protein
- Serine-type endopeptidase inhibitor
- At1g25400
- O-fucosyltransferase 20
- BTB/POZ and TAZ domain-containing protein 5
- At4g16447
- At1g48330
- At5g06790
- Poly polymerase
- At4g19430
Sequence:
MDRQNSDDIMRFLDGMASSDDVLFGFLDEGNQSPEDFSVNLNAGEDDGDEDDNNNNSEDNKAFWQEHEQLLQGTLYRTSSIETKIRQATKEALKQVKSKGLYCVCRRPVDGGCRSCLRGEISRHLRDVAGYDCVISKSKWRSCQDIPAGEHEFIEIVDRSGSKKSEMRVVIELSFRAEFEIAKGSEEYKRLISRLPEVYVGKTERLRSLIKILCIAGKKCLRDKKMHMAPWRKHKYMQAKWLGTCDRSSSLEASVSEAMEPENWVPVAKPRVSMLNYDGLLGGFSAGPATVAVV
Protein: trp operon leader peptide (P0AD92)
Organism: Escherichia coli (strain K12)
Function: This protein is involved in control of the biosynthesis of tryptophan.
Interaction partners:
- Anthranilate synthase component 1
- Bifunctional protein TrpGD
- Tryptophan biosynthesis protein TrpCF
- leu operon leader peptide
- thr operon leader peptide
- ilv operon leader peptide
- 5'-3' exoribonuclease Rnm
- Tryptophan synthase beta chain
- Trp operon repressor
- Tryptophan synthase alpha chain
Sequence:
MKAIFVLKGWWRTS
Protein: Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Q08881)
Organism: Homo sapiens (Human)
Function: Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of ITK to the cell membrane, in the vicinity of the stimulated TCR receptor, where it is phosphorylated by LCK. Phosphorylation leads to ITK autophosphorylation and full activation. Once activated, phosphorylates PLCG1, leading to the activation of this lipase and subsequent cleavage of its substrates. In turn, the endoplasmic reticulum releases calcium in the cytoplasm and the nuclear activator of activated T-cells (NFAT) translocates into the nucleus to perform its transcriptional duty. Phosphorylates 2 essential adapter proteins: the linker for activation of T-cells/LAT protein and LCP2. Then, a large number of signaling molecules such as VAV1 are recruited and ultimately lead to lymphokine production, T-cell proliferation and differentiation. Required for TCR-mediated calcium response in gamma-delta T-cells, may also be involved in the modulation of the transcriptomic signature in the Vgamma2-positive subset of immature gamma-delta T-cells (By similarity). Phosphorylates TBX21 at 'Tyr-530' and mediates its interaction with GATA3 (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17060314}. Nucleus {ECO:0000250|UniProtKB:Q03526}. Note=Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation.
Interaction partners:
- Lymphocyte cytosolic protein 2
- Proto-oncogene vav
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- GRB2-related adapter protein 2
- Growth factor receptor-bound protein 2
- T-cell-specific surface glycoprotein CD28
- T-cell surface glycoprotein CD3 zeta chain
- Phosphatidylinositol 3-kinase regulatory subunit alpha
- Linker for activation of T-cells family member 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Sequence:
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKYHPNFWMDGKWRCCSQLEKLATGCAQYDPTKNASKKPLPPTPEDNRRPLWEPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL
Protein: UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase (EC 6.3.2.45) (Murein peptide ligase) (UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase) (P37773)
Organism: Escherichia coli (strain K12)
Function: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. The enzyme can also use the tetrapeptide L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanine or the pentapeptide L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioyl-D-alanyl-D-alanine in vivo and in vitro.
Subcellular location: Secreted.
Interaction partners:
- Beta-hexosaminidase
- Murein tetrapeptide carboxypeptidase
- UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
- 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
- Anhydromuropeptide permease
- UDP-N-acetylglucosamine--N-acetylmuramyl-
- D-alanine--D-alanine ligase B
- UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
- UDP-N-acetylenolpyruvoylglucosamine reductase
- UDP-N-acetylmuramoylalanine--D-glutamate ligase
Sequence:
MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEKQGIELIQGYDASQLEPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRDRWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSAHLGESDFFVIEADEYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRIIWPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLVGEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHPTAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHIPWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLAKKAEAAQ
Protein: Transposable element P transposase (P-element transposase) (EC 2.7.7.-) (THAP domain-containing protein) (DmTHAP) (Q7M3K2)
Organism: Drosophila melanogaster (Fruit fly)
Function: P-element transposase that specifically mediates transposition of P-elements. Mediates both; precise and imprecise excision.
Interaction partners:
Sequence:
MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAPAKGQTFKRRRLNADAVPSKVIEPEPEKIKEGYTSGSTQTESCSLFNENKSLREKIRTLEYEMRRLEQQLRESQQLEESLRKIFTDTQIRILKNGGQRATFNSDDISTAICLHTAGPRAYNHLYKKGFPLPSRTTLYRWLSDVDIKRGCLDVVIDLMDSDGVDDADKLCVLAFDEMKVAAAFEYDSSADIVYEPSDYVQLAIVRGLKKSWKQPVFFDFNTRMDPDTLNNILRKLHRKGYLVVAIVSDLGTGNQKLWTELGISESKTWFSHPADDHLKIFVFSDTPHLIKLVRNHYVDSGLTINGKKLTKKTIQEALHLCNKSDLSILFKINENHINVRSLAKQKVKLATQLFSNTTASSIRRCYSLGYDIENATETADFFKLMNDWFDIFNSKLSTSNCIECSQPYGKQLDIQNDILNRMSEIMRTGILDKPKRLPFQKGIIVNNASLDGLYKYLQENFSMQYILTSRLNQDIVEHFFGSMRSRGGQFDHPTPLQFKYRLRKYIIGMTNLKECVNKNVIPDNSESWLNLDFSSKENENKSKDDEPVDDEPVDEMLSNIDFTEMDELTEDAMEYIAGYVIKKLRISDKVKENLTFTYVDEVSHGGLIKPSEKFQEKLKELECIFLHYTNNNNFEITNNVKEKLILAARNVDVDKQVKSFYFKIRIYFRIKYFNKKIEIKNQKQKLIGNSKLLKIKL
Protein: Pro-phenol oxidase A1 (EC 1.14.18.1) (Q27598)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTNTDLKALELMFQRPLEPAFTTRDSGKTVLELPDSFYTDRYRNDTEEVGNRFSKDVDLKIPIQELSNVPSLEFTKKIGLKNQFSLFNNRHREIASELITLFMSAPNLRQFVSLSVYTKDRVNPVLFQYAYAVAVAHRPDTREVPITNISQIFPSNFVEPSAFRDARQEASVIGESGARVHVDIPQNYTASDREDEQRLAYFREDIGVNSHHWHWHLVYPTTGPTEVVNKDRRGELFYYMHHQILARYNVERFCNNLKKVQPLNNLRVEVPEGYFPKILSSTNNRTYPARVTNQKLRDVDRHDGRVEISDVERWRDRVLAAIDQGYVEDSSGNRIPLDEVRGIDILGNMIEASPVLSINYNFYGNLHNEGHNIISFAHDPDYRHLEDFGVMGDVTTAMRDPIFYRWHGFIDTVFNKFKTRLNPYNAGELNFDGITVDYIEAKIGKSNTKANTLLTYWQKSSADLAAGLDFGPTTDRNIFASFTHLQNAPFTYTFNVTNNGARRTGTCRIFICPKVDERNQALNLEEQRLLAIEMDKFTVDLVPGENTIRRQSTESSVAIPFERSFRPVGADYQPKAADELARFKFCGCGWPQHLLLPKGNAQGMLFDLFVMISDYSQDSVEQPKTPNDACSTAYSFCGLKDKLYPDRRTMGYPFDRRLPNANLTELVGAFGNMAKTDLRIVFNDRVIDKA
Protein: Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50) (F1LSG8)
Organism: Rattus norvegicus (Rat)
Function: Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Subcellular location: Recycling endosome {ECO:0000269|PubMed:25799061}. Membrane {ECO:0000269|PubMed:31721635}. Note=Associates with membranes in an EIPR1-dependent manner. {ECO:0000269|PubMed:31721635}.
Interaction partners:
- Vacuolar protein sorting-associated protein 53 homolog
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar protein sorting-associated protein 52 homolog
- EARP and GARP complex-interacting protein 1
- Vacuolar protein sorting-associated protein 54
Sequence:
MQKIKSLMTRQGLKSPPESLNDLGAFESLRVPGKEEFRELREQPSDPQAEQELINSIEQVYFSADPFDIVKYELEKLPPVLNLQELEEYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNSRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDVNHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDSEETAAASEGSNVMSTEETNFDRGYVKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIVSRLMQVGEEFCGSKSEVLQESIRKQSINYFKNHHRIRLDELRMFLENETWELCPVKSNFSILQLHEFKFLEQSRSPSVSPSKQPSATSSKPVTLFEQYCSGGNPFEIQADHKDEETEDVLASNGYESDEQEKSAYQDYDSDSDVPEELKRDYVDEQTGDVPVKSVSRETLKSRKKSDYSLNKVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSLESTGLGLSSSRLRTTLNRIQESLIDLEGSADPTATLTAAEERKEKVPSPHLNQLVILTSGDTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPIYWIVAGKAIDYEQMLLLMTNVKWDVKEIMSQHNVYVDALLKEFEQFNKRLNEVSKRVRIPLPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVEIYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDIDRPKR
Protein: Urease subunit alpha (EC 3.5.1.5) (Urea amidohydrolase subunit alpha) (P14916)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01955, ECO:0000269|PubMed:8641799}. Note=Also associates with the outer membrane upon autolysis of neighboring bacteria.
Interaction partners:
- Urease subunit beta
- Urease accessory protein UreG
- Urease accessory protein UreF
- Urease accessory protein UreH
- Urease accessory protein UreE
- Acid-activated urea channel
- Hydrogenase/urease maturation factor HypB
- Arginase
- Phosphoglucosamine mutase
- Glutamyl-tRNA
Sequence:
MKLTPKELDKLMLHYAGELAKKRKEKGIKLNYVEAVALISAHIMEEARAGKKTAAELMQEGRTLLKPDDVMDGVASMIHEVGIEAMFPDGTKLVTVHTPIEANGKLVPGELFLKNEDITINEGKKAVSVKVKNVGDRPVQIGSHFHFFEVNRCLDFDREKTFGKRLDIASGTAVRFEPGEEKSVELIDIGGNRRIFGFNALVDRQADNESKKIALHRAKERGFHGAKSDDNYVKTIKE
Protein: LD24662p (Transport and golgi organization 4) (Q9VYQ9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Pre-mRNA-splicing factor SPF27
- Cell division cycle 5, isoform A
- Puff-specific protein Bx42
- Pre-mRNA-splicing factor syf1 homolog
- Pre-mRNA-processing factor 19
- Splicing factor YJU2
- RE31520p
- Protein CWC15 homolog
- Protein crooked neck
- Pre-mRNA-splicing factor Syf2
Sequence:
MAMEDVQKHSVHTLIFRSLKRTHDLFVSNQGNLPEIDERLEKLRRSIKAKDGYGLVLDKVAKIGEARKASGAQTPGDKTLAITDGSATDAASGAGSLVKYNAGARPAEKTAPLVTGTHTSLVRASLANSNADMSANGAIASHLQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDDEASEESHPINWRPDLLKRRKF
Protein: Cilia and flagella associated protein 68 (E9PS93)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000256|ARBA:ARBA00004611}.
Interaction partners:
Sequence:
MAASQCLCCSKFLFQRQNLACFLTNPHCGSLVNADGHGEVWTDWNNMSKFFQYGWRCTTNENTYSNRTLMGNWNQERYDLRNIVQPKPLPSQDLSESLTGSQDINLNWILPDTNAQKSQLT
Protein: BPTI/Kunitz inhibitor domain-containing protein (A5A8R1)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MHLFLLFIPHVIAVKDLAWYSANPVLSSSHPVGPAAIQAATAIDFCQLPVDTGKCSQQLVRYYYDAAVDECKRFTFSGCGGNSNRFMRRAHCRNRCVKQPNKPEVQELKHRRTVTSTTSTPFQTVNEESTVEPSATKRLPVTLPVKKLELVQVRIFNKTESGHGNGLCQDCDPLYGTCLDGKCGCMKGFRSLGKVCIDLNECDNGAVCGPNARCVNEIGSFQCVCDAGFSTDGDCKIGQEACMDEFDVNLTEEDCNNGKQEIKYYYDADSVQCKQFFYGGCKTTSRNFFADLQTCDVICVSNQRDYLKSKGQSLSHHPVLEISSDLNNGNDLKSNHYKIDLFSSPSSPVTPNRPLSADDWPLKPITLKPALNLDFSQGKTKSTAEKHKEADDAEILVHQLTPEHNSCDLKFEPVLREECISADWAEKFFWNSEFKDCEPFWYDSSCDPRDRAGKNFFETFEDCKNKCDGVQSQYVVPITTVPDEQSKIEEVETSETPGIVDETTTTAAPEEESEENGFFFKVKPQNYLEDVLSSETEETQHYGFNPNEFLKQNSQNQKPTEITEILRILPAQTEHDEASELKKEDKIEHDILEHLKNKEPTEKVLSTPSTCDLEYDDALRNECTSADWTELYYWNAQFKECEAFWYDSSCGDQDFSKKNLFKNFDDCNNQCVKKIGEALKKMDPETTTTTSTTTTTTTAPTTTKMEEPKRSNYKQSDPLNLILNKALNPDESSELPEKFPPAHEQGFVNFAIKSEVTATTKFDRLKYMAEFRKKLLALPDNFSTTPKQSSPTSSPTTTRMRSPSTHKSTVSQATKTASSTPQSPSTTTSFDDFVEKEKKTVLETIKILDRPEDLCDEPLHPKLEEDCKNDQWEIQWFFNSDRGACKSFWYGGCEIESRNFFPDHAVRFFGKILRNVSIIAELSTFLCSQVCYTCKFLIESLHSARRVEHSCSSP
Protein: Methylesterase 8 (AtMES8) (EC 3.1.1.-) (O80475)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Methylesterase shown to have carboxylesterase activity in vitro.
Interaction partners:
- Glutathione S-transferase U26
- Large ribosomal subunit protein eL18y
- Xyloglucan endotransglucosylase/hydrolase protein 19
Sequence:
MYENGISFIISLLICGCVKSEEMMKQHFVLVHGSCLGAWCWYKVKPLLEASGHRVTALDLAACGIDTRSITDISTCEQYSEPLIQLMTSLPNDEKVVLVGHSYGGLTLAIAMDKFPDKISVSVFVTSFMPDTKNSPSFVLEKFASTMTPEDWMGSELEPYVVFSAEFTKHRILQLSPIEDLELRLLLKRPGSLFLNDLSRMKNFSEKGYGSVPRAYIVSKDDHTISEEYQRWMIDNYPPNLVIEMEGTDHLPLFCKPQLLSDHLLAIADKFS
Protein: 11 kDa protein (Q6TV08)
Organism: Human parvovirus B19 (HPV B19)
Interaction partners:
Sequence:
MQNNTTDMDMKSLKNCGQPKAVCTHCKHSPPCPQPGCVTKRPPVPPRLYLPPPIPIRQPNTKDIDNVEFKYLTRYEQHVIRMLRLCNMYQNLEK
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Q7ZVQ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- U4/U6 small nuclear ribonucleoprotein Prp4
- PRP3 pre-mRNA-processing factor 3 homolog
- U4/U6 small nuclear ribonucleoprotein Prp31
- NHP2-like protein 1
- NHP2-like protein 1
- Small nuclear ribonucleoprotein polypeptide F.
- Elongation factor Tu GTP-binding domain-containing 2.
- WW domain-binding protein 4.
- Ran-specific GTPase-activating protein
- Pre-mRNA-processing factor 8.
Sequence:
MNVQPSNPNNPIVFFDVSIGGQEVGRMKIELFADIVPKTAENFRQFCTGEFKKDGVPVGYKGCTFHRVIKDFMIQGGDFVNGDGTGICSIYRGPFADENFRMKHSGPGLLSMANSGPGTNGCQFFITCTKCDWLDGKHVVFGKVVDGLLVMRKIEAVVFINFIGTAQNKISSTITLPNADL
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Q8IIK3)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Uncharacterized protein
- Nucleoporin NUP221, putative
- WD repeat-containing protein
- Ran-specific GTPase-activating protein 1, putative
- PRE-binding protein
- Probable DNA repair protein RAD50
Sequence:
MSLSIHTNYGDIKIELFCYEVPKTCKNFLALCASGYYDNTKFHKNIKGFAIQGGDPTNTGKGGQSIYGKYFEDEFDSTLKHDKRGIVSMANKGKPNTNGSQFFITYSRQPHLNGIYPVFGKVIDGMDVLSVLENEPVGEKSRPIKDIIIETITIHANPIAEEESVDN
Protein: Estrogen related receptor beta (E7EWD9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR002527}.
Interaction partners:
Sequence:
MLLNRMSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
Protein: Phosphatidylinositol 4-phosphate 5-kinase 4 (AtPIP5K4) (EC 2.7.1.68) (1-phosphatidylinositol 4-phosphate kinase 4) (Diphosphoinositide kinase 4) (PtdIns(4)P-5-kinase 4) (Q9M1K2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Phosphatidylinositol 4-kinase beta 1
- Phosphatidylinositol 4-kinase beta 2
- Phosphoinositide phospholipase C 3
- Phosphatidylinositol 4-kinase alpha 2
- Syntaxin-124
- Phosphatidylinositol 4-kinase alpha 1
- CRIB domain-containing protein RIC5
- Phosphoinositide phospholipase C 1
- Phosphoinositide phosphatase SAC7
- Rac-like GTP-binding protein ARAC11
Sequence:
MSKEQSCVLKAWEVTVRKTQQAKKRANSIFGTVSVAPQTDDDATTTTEENDDETSTNRSSIGELYHAERILPNGDYYTGQWYDSFPHGHGKYLWTDGCMYIGDWYNGKTMGRGKFGWPSGATYEGEFKSGYMDGVGLYTGPSGDTYKGQWVMNLKHGHGIKRFANGDVYDGEWRRGLQEAQGKYQWRDGSYYMGEWKNATICGKGTFIWTDGNRYDGFWDDGFPRGNGTFKWADGSFYVGHWSNDPEEMNGTYYPSGDDGSPEWDPKDVFTNLSEYKICSGERVPVLPSQKKLSVWNSSKRVEKPRRMSVDGRVSVGVDRAFEKMNMWGTESGEGAADIDSTTRRDLDAEMMRLEAEGFIQSLRPSPAPMRLPRAGRKQGETISKGHRNYELMLNLQLGIRHAVGKQAPVVSLDLKHSAFDPKEKVWTRFPPEGTKYTPPHQSSEFKWKDYCPLVFRSLRKLFKVDPADYMLSICGNDALRELSSPGKSGSFFYLTNDDRYMIKTMKKSETKVLLRMLAAYYNHVRAFENTLVIRFYGLHCVKLTGPIQKKVRFVIMGNLFCSEYSIHRRFDLKGSSLGRTTDKPESEINSNTILKDLDLNFIFRLQKAWYQEFIRQVDKDCEFLEQERIMDYSLLVGIHFREASVAGELIPSGARTPIGEFEDESAPRLSRADVDQLLSDPTRWASIRLGGNMPARAERTMRRSDCEFQLVGEPTGEYYEVVMIFGIIDILQDYDISKKLEHAYKSIQYDPTSISAVDPRLYSRRFRDFIFKVFTEDN
Protein: Ferritin-1, chloroplastic (AtFer1) (EC 1.16.3.1) (Q39101)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Ferric reduction oxidase 2
- Fe
- Metal transporter Nramp4
- Metal transporter Nramp3
- Ferric reduction oxidase 3, mitochondrial
- Nicotianamine synthase 3
- Probable nicotianamine synthase 4
- Transcription factor ORG2
- Transcription factor ORG3
- Protein PHR1-LIKE 1
Sequence:
MASNALSSFTAANPALSPKPLLPHGSASPSVSLGFSRKVGGGRAVVVAAATVDTNNMPMTGVVFQPFEEVKKADLAIPITSHASLARQRFADASEAVINEQINVEYNVSYVYHSMYAYFDRDNVAMKGLAKFFKESSEEERGHAEKFMEYQNQRGGRVKLHPIVSPISEFEHAEKGDALYAMELALSLEKLTNEKLLNVHKVASENNDPQLADFVESEFLGEQIEAIKKISDYITQLRMIGKGHGVWHFDQMLLN
Protein: Vesicle-fusing ATPase (EC 3.6.4.6) (I3L0N3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU367045}.
Interaction partners:
Sequence:
MQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGASPLDFD
Protein: Myocardial zonula adherens protein (Q5EB94)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in cellular signaling via Rho-related GTP-binding proteins and activation of transcription factor SRF. Targets TJP1 to cell junctions (By similarity). In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20093627}. Cell membrane {ECO:0000269|PubMed:18849881, ECO:0000269|PubMed:20093627}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q3UIJ9}; Cytoplasmic side {ECO:0000250|UniProtKB:Q3UIJ9}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000250|UniProtKB:Q3UIJ9}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:Q3UIJ9}. Cell junction {ECO:0000269|PubMed:29445566, ECO:0000269|PubMed:31384490}. Note=Detected predominantly at the intercalated disk in cardiomyocytes, and at low levels on sarcomeric Z disKs. Colocalizes with F-actin. Colocalizes with cortical actin (PubMed:20093627). In neurons, colocalizes with GRIN1 in postsynaptic neurites (PubMed:18849881). In heart, localizes at area composita, the mixed-type junctional structure composed of both desmosomal and adherens junctional proteins (PubMed:31384490). {ECO:0000269|PubMed:18849881, ECO:0000269|PubMed:20093627, ECO:0000269|PubMed:31384490}.
Interaction partners:
- DNA-directed RNA polymerase subunit
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase subunit beta
- RNA polymerase II subunit J
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase subunit
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
Sequence:
MLRSTSTVTLLSGGSAKSPGTPSRRANVCRLRLTVPPENPVPQQKEKKIERKDQPPELSNGESTKKLPQGVVYGVVRRSDPNQQKEMVVYGWSTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQDLSVSHAQQDYLDSHIQAQASALDSFNAMNSALALDSVGLQKTLVDVTLENSNIKDQIRHLQQTYEASMDKLREKQRQLEAAQMENQLLKMRVESSQEANAEVMREMTRKLYSQYEEKLQEAQRKHSAEKEVLLEETNSFLKAIEEANKKMEAAELSLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGEMADFDKNRYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPKTEVETREIGVGCDLLPSTTGRTREIAVPSRSYTPYTRVLELTSKKTLT
Protein: E3 ubiquitin-protein ligase IE2 (EC 2.3.2.27) (Immediate-early protein IE2) (RING-type E3 ubiquitin transferase IE2) (P24647)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection. Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral transcription and replication by targeting and ubiquitinating host proteins. Acts as a transcriptional activator and activates a number of viral promoters including itself, IE1 and the promoter of 39K gene.
Subcellular location: Host nucleus {ECO:0000269|PubMed:11262179, ECO:0000269|PubMed:11967334, ECO:0000269|PubMed:8009830}.
Interaction partners:
Sequence:
MSRQINAATPSSSRRHRLSLSRRRINFTTSPEAQPSSSSRSQPSSSSRSHRRQERRQEQRVSEENVQIIGNVNEPLTRTYHRQGVTYYVHGQVNISNDDPLLSQEDDVILINSENVDRERFPDITAQQYQDNIASETAAQRALQRGLDLEAQLMNEIAPRSPTYSPSYSPNYVIPQSPDLFASPQSPQPQQQQQQQSEPEEEVEVSCNICFTTFKDTKNVNSSFVTSIHCNHAVCFKCYVKIIMDNSVYKCFCSATSSDCRVYNKHGYVEFMPINVTRNQDSIKQHWRELLENNTVNNHTTDLNYVEQLQKELSELRAKTSQVEHKMTMLNSDYIMLKHKHAVAELDLQKANYDLQESTKKSEELQSTVNNLQEQLRKQVAESQAKFSEFERSNSDLVSKLQTVMSRR