Protein: Protein CELLULOSE SYNTHASE INTERACTIVE 3 (F4I718)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulator of the microtubular cytoskeleton (By similarity). Microtubule-associated protein involved in the association of cellulase synthase (CESA) complexes (CSCs) and cortical microtubules. Promotes dynamics of CSCs in the plasma membrane in both microtubules-dependent and microtubules-independent manners. Regulates primary cell wall biosynthesis and cellulose microfibrils organization.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24368796}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:F4IIM1}. Endomembrane system {ECO:0000269|PubMed:24368796}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24368796}. Note=Colocalizes with cellulase synthase (CESA) complexes (CSCs) in a CSI1-dependent dynamic way. Present with cortical microtubules. {ECO:0000269|PubMed:24368796}.
Interaction partners:
- Cellulose synthase A catalytic subunit 6
- Protein CELLULOSE SYNTHASE INTERACTIVE 1
- Protein TRACHEARY ELEMENT DIFFERENTIATION-RELATED 6
- Cyclin-U3-1
- Cellulose synthase A catalytic subunit 5
- Cellulose synthase A catalytic subunit 7
- Cyclin-U1-1
Sequence:
MLKAFLPGTQEEETLSSLQSGKVDAKMEMDDPEKAMATVAQLIEQLHAKTSSPQDKELTTARLLGIAKGKREARRLIGSYGQAMPLFISMLRNGTTLAKVNVASILCVLCKDKDLRLKVLLGGCIPPLLSVLKSGTMETRKAAAEAIYEVSSAGISNDHIGMKIFITEGVVPTLWDQLSLKGNQDKVVEGYVTGALRNLCGVDDGYWRLTLEGSGVDIVVSLLSSDNPNSQANAASLLARLVLSFCDSIQKILNSGVVKSLIQLLEQKNDINVRASAADALEALSANSDEAKKCVKDAGGVHALIEAIVAPSKECMQGKHGQSLQEHATGALANVFGGMRHLIIYLGQVSQSPRLTEPIGDVIGALAYALMIFKQPESSENIFDPSVIESILVKLLKPRDTKLIQERILEAMASLYGNSSLSCYLDDAEAKRVLIALITMASADVRERLIICLSGLCHDKVGIWEAIGKREGIQLFISFLGLSSEQHQEYAVEMLKILTAQVDDSKWAVTAAGGIPPLVQLLETGSQKAKEDAACILWNLCCHSEEIRDCVERAGGIPAFLWLLKTGGPNSQETSAKTLVKLVHTADPATINQLLALLLGDDPTSKIQVIEVLGHVLSKASQEDLVHRGCAANKGLRSLVESLTSSREETKEHTASVLADLFSSRQDICGHLATDDIINPWIKLLTNNTQNVAKQVARALDALSRPVKNNNNKKKSYIAEGDIKSLIKLAKNSSIESAENAVSALANLLSDPDIAAEALAEDVVSAFTRILADGSPEGKRNASRALHQLLKNFPVCDVLKGSAQCRFAILSLVDSLKSIDVDSADAFNILEVVALLAKTKSGVNFSYPPWIALAEVPSSLETLVQCLAEGHTLVQDKAIEVLSRLCSDQQFLLSELIVSRPKSMLVLADRIVNASSLEVRVGSTALLLCAAKEKKQLITETLDQSGFLKLLLHALVDMIKHNSTSFSLETEVQTPKGFLEKNVFQDTGSFYFPDPAKILGGTVALWLLCILTSVDAKSKVIVMEAGGLEVLVGKLARYTSSAQAEFEDTEGIWISALLLAIMFQDDNVSFSSTTMRIIPTLAVLLGSDELIDRYFAAHAMASLVCTRNRGINLTIANSGAVSGIINLLGYVESEILNLVALANEFSLVKEPDQVILQHLFEIEDVRLGSTARKSIPLLVDLLRPIPDRPGAPQFAVQILIRIADGSDTNKLLMAEAGAVEALTKYLSLSPQDSTEYAISELLRVLFSNHELRQNEMALSSLNQLIAVLRLGSRSARYSAAGALNELFDAENIRNSEIACQAVQPLMDILGSVSESEQEVALSALIKLSSGNTSNTALLIDVEGSLLENVIKILSSATASEELKINAARLCSVVFSNKNIRTSASASGCMKPLITLMQSERSAAVEAAVFAIKILLDDEQHLELAAAHNIQELLVGLVSGKNYVIIEASLSALIKLGKDRVPRKLDMVEAGIIERCLELLPGASSSLCSAVVELFRILTNSGVIARRPDVAKTVEPLFAVLLRSDLTLWGQHSALQALVNILEKQQTLEAFSFTPSEAIVPLISFLESSSQAIQQLGAELLSHFLTMEDFQQDITTQSAVVPLVRLAGIGILSLQETAIKALEKISASWPKAVLDAEGIFELSKVILQEDPQPPLDLWESAAFVLSNILQYDAECFFRVELPVLVKLLFSTIESTVLLALKALMLHEKNDASSTVQMAELGAIDALLDLLRSHQCEEESGSLLEVIFNNPRVRELKLCKYAIAPLSQYLLDPHTRSEPGRLLAALALGDLSQHEGLSRSSGSVSACRALISVLEEQPTEEMKVVAICALQNFVMNSRTNRRAVAEAGGVLLIQELLLSCNPEVSGQAALMVKFLFSNHTLQEYVSNELIRSLTAALERGLWSTATINIEVLRTLNVIFSNFPKLRASEAATFCIPHLVGALKSGVEDVQGLVLDILYLLRHSWTNMSIDVAKSQAMIAAEAIPVLQMLMKTCPPRFHDKADSLLHCLPGCLTVNVMRANNLKQSMATTNAFCQLTIGNCPPRQTKVVSNSTTPEWKEGFTWAFDVPPKGQKLHIICKSKSTFGKTTLGRVTIQIDKVVTEGEYSGSLSLNHENSKDASSRSLDIEIAWSNRTTDETH