wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial FAD carrier protein FLX1 (P40464)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transport of FAD from the cytosol to the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein.
Interaction partners:
- Flavin adenine dinucleotide synthase
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Riboflavin kinase
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Succinate dehydrogenase cytochrome b subunit
- Uncharacterized protein YMR178W
- Dihydrolipoyl dehydrogenase, mitochondrial
- Succinate dehydrogenase assembly factor 2, mitochondrial
- mRNA-binding protein PUF3
- Mitochondrial chaperone TCM62
Sequence:
MVDHQWTPLQKEVISGLSAGSVTTLVVHPLDLLKVRLQLSATSAQKAHYGPFMVIKEIIRSSANSGRSVTNELYRGLSINLFGNAIAWGVYFGLYGVTKELIYKSVAKPGETQLKGVGNDHKMNSLIYLSAGASSGLMTAILTNPIWVIKTRIMSTSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGLVPALFGVSQGALYFAVYDTLKQRKLRRKRENGLDIHLTNLETIEITSLGKMVSVTLVYPFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGLYKGLSANLVRAIPSTCITFCVYENLKHRL
Protein: Fatty acyl-CoA reductase (EC 1.2.1.84) (Q57TU9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable enoyl-CoA hydratase, mitochondrial
- glucose-6-phosphate 1-epimerase
- Aldehyde dehydrogenase
- Alkylglycerone-phosphate synthase
Sequence:
MPLDVHEAFSRKNFFLTGGTGFMGKVLIYKIMKEFPDVGYIYVLARGKNSRRLKRYLNPQERVKLEVLSSPCFDPLRKSMGEAAFNALGSRVVAIEGNIVDNRIGLSDKDRQTLINHTHFIVHMAATVNFDERLNIAVETNTLGSLRVLTLAKECKNLEAMVHVSTCYVNYSVQGRPVEECLYSPPFDPQGMCKHILALNDKEIDTVGRDLLKKYGFPNTYTFTKFIGEQLLNENKGNCPLVIVRPSIVGCSLKEPFPGWVDALTAAGGLILTCGLGLVRELVCRQGAIADIVPVDFVVNVILKALFQAKTHFKGNTPKVVNVDEHARERSTAASTAQGLLNPLTAAKQLNGTGKGALKGVYEGNPASIFQQQQQQQNHASNNGGGHINNDNDQGQQQQQQRDTGGPVVAMAGSDVYGTSVPFIYQASTSHSHNHITWRRMSDASIEYWSAKKRHPKALGPVSVQFMESRLLYAMKFFLCREVPSHALAFLADLPEPIGSKSKRENVKKLKRALFRAKDLNRQFVAFTCTEWVFAATNTMSLDEGLSERSRSAFYYDPYLINWWSYCHWYSYGLLKHIVRDTGSFEEPEQPETAAELFRRASSL
Protein: Interleukin-18 (IL-18) (Interferon gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma) (O19073)
Organism: Sus scrofa (Pig)
Function: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q14116}. Secreted {ECO:0000250|UniProtKB:Q14116}. Note=The precursor is cytosolic. In response to inflammasome-activating signals, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1, CASP4 or CASP5 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10. {ECO:0000250|UniProtKB:Q14116}.
Interaction partners:
- Caspase-1
- Interleukin-1 receptor-like 1
- Apoptosis-associated speck-like protein containing a CARD
- Interleukin-1 beta
- Interleukin-18 receptor accessory protein
- Multifunctional fusion protein
- Interleukin-6
- Interleukin-10
- RELA proto-oncogene, NF-kB subunit
- Nuclear factor NF-kappa-B p105 subunit
Sequence:
MAAEPEDNCISFVEMKFINNTLYFVAENDEDLESDYFGKLEPKLSIIRNLNDQVLFINQGHQAVFEDMPDSDCSDNAPQTVFIIYMYKDSLTRGLAVTISVQCKKMSTLSCKNKTLSFKEMSPPDNIDDEGNDIIFFQRSVPGHDDKIQFESSLYKGYFLACKKENDLFKLILKEKDECGDKSIMFTVQNKN
Protein: Site-specific recombinase IntIA (Q87NK3)
Organism: Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Interaction partners:
Sequence:
MKSQFLLSVKEHMLTRYYANKTIESYLFWIKRFIVFHQFAHPSKLSEDDVIRFLSHLAIDEKVAVKTQALALNAISFLYRDFFKTPLSLDMRFQKSLTEKKLPVVLTRDEVRRFVQHIDPRYKLHIQLLYGSGLRIMECLRLRIQDIDYDYGAVRVWQGKGGKNRTVTLAKELHEPLKSQMNFARNYYFKDRHVPGYAGVYISEGLRRKYPNAELDFNWHFLFPSNKLSVDKETGQLRRHHINESAIQRAVKRSALDANIEKTVTCHTLRHSFATHLLESGADIRTVQEQLGHTDVKTTQIYTHVIERGAGGVLSPLSSL
Protein: Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase) (P97820)
Organism: Mus musculus (Mouse)
Function: Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase 1
- Striatin
- Striatin-4
Sequence:
MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTVTAAIKVMDVTEDEEEEITLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGGPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLHDHRRPHAQQQPPPPQQQDRSKPSFHAPEPKPHYDPADRAREVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEGLSQSSDSKSEVPEPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGGGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSPRQESAAKKPDDKKEVFRSLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSPNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGLRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELLHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCGRNDKVFFSSVRSGGSSQVYFMTLGRTSLLSW
Protein: Elongation factor 1-alpha (Q6FMI3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome L complete sequence
- Candida glabrata strain CBS138 chromosome L complete sequence
- Candida glabrata strain CBS138 chromosome F complete sequence
- Transcription factor
- Candida glabrata strain CBS138 chromosome F complete sequence
- Protein-lysine N-methyltransferase EFM4
- Heat shock transcription factor
- Small ribosomal subunit protein uS5
- GTP-binding nuclear protein GSP1/Ran
- Small ribosomal subunit protein eS1
Sequence:
MGKDKQHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYHVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFAEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNASWYKGWEKETKAGVVKGKTLLEAIDAIEPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLTEGLPGDNVGFNVKNVSVKEIRRGNVCGDSKNDPPKAAASFNATVIVLNHPGQISAGYSPVLDCHTAHIACKFEELLEKNDRRSGKKLEDSPKFLKSGDAALVKFVPSKPMCVEAFSDYPPLGRFAVRDMRQTVAVGVIKSVDKTDKAGKVTKAAQKAAKK
Protein: Liver X receptor (Nuclear receptor subfamily 1 group H member 3) (Q8JHU1)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MGPTQLSTQDHGKRVASVFEMEEEGLSLFSGSENPPKHAENPPLKRKKGPAPKMLGNEVCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAQYVCKNGGKCEMDMYMRRKCQECRLRKCQEAGMREQYVLSEEQIRLKKLKKQEDDQARTVVVRPNPPQPPSPSHQLTPEQLNMIEKLVAAQQQCNQRSFTDRLKVTPWPQVPDPNNREARQQRFAHFTELAIISVQEIVDFAKQLPGFRELTREDQIALLKTSTIEVMLLETSRRYNPEIESITFLKDLSYNRDDFAKAGLQFEFINPIFEFSKGMNELQLNDAEYALLIAINIFSADRPNVQDQSLVERLQHTYVEALHSYICINRPNDHLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Protein: A kinase (PRKA) anchor protein 10 (A-kinase anchor protein 10, mitochondrial isoform X1) (F1QDF6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSFFRRKAKGKEPERPADAKASKAPVSPHSPSLSGRNHHAILEAAGPSHVAISAISANMDSFARGRTAILKKQPSHMEAAHFGDLGRSSVNYQIQETRSRLSKTVDQILRDNVALPYFIQFMETRSAEHLVRFWLEAESFRSTSWSRVRAHSLNSVKHSTLAEPAAALGSPDSPDSPNHSSRPLNLDEGDEEDAFSSRTSSRPHTPSPQDTNSHSGALMSHRDSVSFDGTAQPGTLQLQPALRSETPTRQTSSRTGTPVKGLRELSDKLMKSIERDAVNIFTKYISPDAARPIPITEQIRNDIVAKICGEDGQVDPNCFVIAQSVVFSIIDQQHFTEFLRSHYFCKYQIEVLTSGSVFLADILFCESALFYFSEYMEKEDAMNVLQFWLAAENFQDQLAAKKGQYDGQEAQNDAMILYDKYFSLQATNPLGFGDSVRMEIESNICREGGPLPDCFNTPLRQAWTTMEKVYMPGFLSSNLYYKYLSDLINSVRVDEFIGGNANTPNQGWTQEGERNSSVTEGSHVQLQQGTKKAAIKILKNFDEAITVDIASLDPESLYQRPYAGRMTFGKVNELGQFIREAEPEPDVKKSKGSMFSLAMKKWVQGNSDEAQEEMAWKIAKMIVNDVMQQGHHGSPEVKATKL
Protein: GATA-type domain-containing protein (G5EB07)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- NSDC
- C2H2 type master regulator of conidiophore development brlA
- Conidiophore development regulator abaA
- Developmental and secondary metabolism regulator veA
Sequence:
MGSLEAGHRHRDHLPAIGFIGSRGPTTSPAPLVSPTTMYPNNPLPYSYSTTPANVGPGYASPPEPRRAEDEKEKAPRQSLPSIHEALGNDNPLPYPPAPTSAAPQQPNSAPPPHHLPNFGRSSAEGPSGPPNPFSNGSSFLRESSSSHQPQLQAEPSRSSLASLNTTDSRNASLQSISSGKSPTQSASTVMTSVSGSQTGTGYDYNAPPSAGSVASPNGYSGFSQPFPFQSQPPPGAPVYPAASYDSRPYEMKGGVTGSFGHQGDSAKRHLDVYDIESSLTEMVDLNTRALDFSRHYANRAHQSRSGAVVGSALPSLHEVEEMLNIQRRNHDALMRIRAVVFSQEHAMAEQVAQRKAFKFGGAHDDDHRMAMYQEEFKSSGGFGPDSKKRRGKAAPPGRCHSCNRAETPEWRRGPDGARTLCNACGLHYAKLTRKMGAKQAAGLGSNLKPKTLDSVSPRSH
Protein: Transmembrane protein 161A (Adaptive response to oxidative stress protein 29) (AROS-29) (Q9NX61)
Organism: Homo sapiens (Human)
Function: May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPRPRGRKERWANGLSEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFTEAYYYMLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEGGERSVCLTFAFLFLLLAMLVQVVREETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGAFLTFPGLRLAQTHRDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGETRFSLLSDSAFDSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPIGSGEDEVQQTAARIAGALGGLLTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQHLAGS
Protein: Zinc finger protein 26 (Zinc finger protein KOX20) (P17031)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MATSFRTASCWGLLSFKDISMEFTWDEWQLLDSTQKYLYRDVILENYHNLISVGYHGTKPDLIFKLEQGEDPWIINAKISRQSCPDGWEEWYQNNQDELESIERSYACSVLGRLNLSKTHDSSRQRLYNTRGKSLTQNSAPSRSYLRKNPDKFHGYEEPYFLKHQRAHSIEKNCVCSECGKAFRCKSQLIVHLRIHTGERPYECSKCERAFSAKSNLNAHQRVHTGEKPYSCSECEKVFSFRSQLIVHQEIHTGGKPYGCSECGKAYSWKSQLLLHQRSHTGVKPYECSECGKAFSLKSPFVVHQRTHTGVKPHKCSECGKAFRSKSYLLVHIRMHTGEKPYQCSDCGKAFNMKTQLIVHQGVHTGNNPYQCGECGKAFGRKEQLTAHLRAHAGEKPYGCSECGKAFSSKSYLVIHRRTHTGERPYECSLCERAFCGKSQLIIHQRTHSTEKPYECNECEKAYPRKASLQIHQKTHSGEKPFKCSECGKAFTQKSSLSEHQRVHTGEKPWKCSECGKSFCWNSGLRIHRKTHK
Protein: ATPase family AAA domain-containing protein 2B (Q9ULI0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:24561620, ECO:0000269|PubMed:25593309}. Note=Partially localizes to replication sites.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase, mitochondrial
Sequence:
MVNTRKSSLRLLGSKSPGPGPGPGAGAEPGATGGSSHFISSRTRSSKTRAASCPAAKAGGSGGAGVTLDEARKVEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKSRSTGQREEWNLSTGQARLTSQPGATLPNGHSGLSLRSHPLRGEKKGDGDLSCINGDMEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRRNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVSTEGEEEESQEEDGDIEVEEAEGEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSSDEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQIYASSHKLQLDVSSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPLLERSFNNILAVLQKVFPHAEISQSDKKEDIETLILEDSEDENALSIFETNCHSGSPKKQSSSAAIHKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWEAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYIQRPIEEDRRKFFQELILNQASMAPPRRKHAALCAMEVLPLALPSPPRQLSESEKSRMEDQEENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLKDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSVTSEQINPHSTGARKTETRVEEAFRHKQRNPMDVWHNSANKCAFRVRRKSRRRSQWGKGIIKKRKVNNLKKDEEDTKFADYENHTEDRKLLENGEFEVSTDCHEENGEETGDLSMTNDESSCDIMDLDQGQRLNNGAGTKENFASTEEESSNESLLVNSSSSLNPEQTSRKETFLKGNCLNGEASTDSFEGIPVLECQNGKLEVVSFCDSGDKCSSEQKILLEDQSKEKPETSTENHGDDLEKLEALECSNNEKLEPGSDVEVKDAELDKEGASKVKKYRKLILEQAKTTSLELVPEEPSEPVPPLIVDRERLKKLLDLLVDKSNNLAVDQLERLYSLLSQCIYRHRKDYDKSQLVEEMERTVHMFETFL
Protein: Galanin receptor 1b (Galanin receptor type 1b) (F1QF39)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Galanin peptides
- Galanin peptides-like precursor
- Pro-melanin concentrating hormone-like protein
- Spexin prohormone 1
Sequence:
MLVIMGLSRNETVIWTEEHMDTNQTTDTFGPEVVIVPVIFGCIFFLGIIGNTLVMVVIGKIKSRRSRSTTNIFILNLSIADLSFLLFCVPFQATIYSLPEWIFGAFLCKFVHYFVMVSMLVSIFTLVAMSVDRYIAVVLSKKSPCIRNRRNALIGVCVIWMLSFIFAVPVAQHQILTDHPKAPNSTFCWEIWTERVAKHTYKVTILVIGYLLPLLLITCCYAKVLYHLHKKIKNMSKKSERSKRKTAQTVLLVVAAFLICWMPHHIIAMWVEFGQFPLNDASFAFRIISHCLAYGNSCVNPILYAFLSENFRKACKQVFTCRFFYSPPPVEKVVRIRMENFSMTHSTTNI
Protein: Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles-like protein 2) (Q04743)
Organism: Homo sapiens (Human)
Function: Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q04744}. Cell projection, axon {ECO:0000250|UniProtKB:Q04744}. Note=Detected in axons within the olfactory mucosa and glomeruli in the olfactory bulb. {ECO:0000250|UniProtKB:Q04744}.
Interaction partners:
- Paired box protein Pax-2
- Transcription factor Sp8
- Forkhead box protein G1
- Eukaryotic translation initiation factor 4E
- Neurogenin-2
Sequence:
MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD
Protein: Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific) (P09041)
Organism: Mus musculus (Mouse)
Function: Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
- Bisphosphoglycerate mutase
- Phosphoglycerate mutase 2
- Phosphoglycerate mutase 1
- Glyceraldehyde-3-phosphate dehydrogenase
- Glucose-6-phosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Phosphoglycerate kinase 1
Sequence:
MALSAKLTLDKVDLKGKRVIMRVDFNVPMKNNQITNNQRIKAAIPSIKHCLDNGAKSVVLMSHLGRPDGIPMPDKYSLEPVADELKSLLNKDVIFLKDCVGPEVEQACANPDNGSIILLENLRFHVEEEGKGKDSSGKKISADPAKVEAFQASLSKLGDVYVNDAFGTAHRAHSSTVGVNLPQKASGFLMKKELDYFSKALEKPERPFLAILGGAKVKDKIQLIKNMLDKVNFMIIGGGMAYTFLKELKNMQIGASLFDEEGATIVKEIMEKAEKNGVKIVFPVDFVTGDKFDENAKVGQATIESGIPSGWMGLDCGPESIKINAQIVAQAKLIVWNGPIGVFEWDAFAKGTKALMDEVVKATSNGCVTIIGGGDTATCCAKWGTEDKVSHVSTGGGASLELLEGKILPGVEALSNM
Protein: apyrase (EC 3.6.1.5) (Q9VZ32)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Apyrase
- Uncharacterized protein, isoform C
- Adenylosuccinate lyase
- Adenine phosphoribosyltransferase
- 5'-nucleotidase
- Adenylosuccinate synthetase
- 5'-Nucleotidase C-terminal domain-containing protein
- Bifunctional purine biosynthesis protein ATIC
- Inosine-5'-monophosphate dehydrogenase
- purine-nucleoside phosphorylase
Sequence:
MATACNRLTWSLVVVVAVMAVMCSSAEAADKEGFPVAIIHINDLHARFEATDTSGGTCDEGEECIGGYPRTVYTVKRLLQEQAELNPIYINAGDSFQGTLWYNIGRWNVTQQLLNLLPADVMTLGNHEFDHGVEGVVPFLETVDTNMLVANMDCAHEPTMEGKYNKSMIIERSGRKIGVIGVILETTYDLANTGKVIFRNESDTIREEAQLLKAQGANIIIVVSHCGYDVDQQIAANAGDWIDVIVGSHSHTFLYTGDPPGPHTPSGDYPTEVIHSSGHRVLIVQASAYARYVGNLIVYFDDNGDVLDYEGDPLYMDQSVPEDDIVLQAMVPWQLEMKPIAERTVGQSRVNLQQSQCSSGECNLGNFFTDAMLHAFVKDASSSSEESWSNVTIALTSTGTFRVPIPAGNITYKQLFAMCPWQNRLVTLSLRGKHIVELLEHVVAPMNASSATPRSSRFLQVSGLRIRYDLNADQRVFSVRVRCSKCLVPRYIPLDLEHKYRVVVMEYLANGKNGFSVISENAEDPEFGPFDLDALMDYMNSTGPITTAIEQRIQFVTT
Protein: Suppressor of variegation 2-10, isoform H (A1Z7P7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTNLELLAPKVQEVYAQSVQEQNATLQYIDPTRMYSHIQLPPTVQPNPVGLVGSGQGVQVPGGQMNVVGGAPFLHTHSINSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQKVEVISDDIELISDDAKPVKRDLSPAQDEQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVASSTSNGSGGGQRAYTPAQQPQQSGTLDPFLQ
Protein: N-carbamoyl-D-amino acid hydrolase (EC 3.5.1.77) (D-carbamoylase) (Q5S260)
Organism: Ensifer adhaerens (Sinorhizobium morelense)
Function: Catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding D-amino acids. Hydrolyzes aromatic and aliphatic N-carbamoyl-D-amino acids in vitro. Effectively hydrolyzes N-carbamoyl-D-p-hydroxyphenylglycine and N-carbamoyl-DL-p-hydroxyphenylglycine, and to a lesser extent N-carbamoyl-D-methionine. No activity for N-carbamoyl-L-amino acids, N-carbamoyl-beta-alanine or (RS)-alpha-ethyl-N-carbamoylphenylglycine in vitro.
Interaction partners:
Sequence:
MTRQMILAVGQQGPIARAETREQVVVRLLYMLTKAASRGANFIVFPELAFTTFFPRWHFTDEAELDSFYETEMPGPVVRPLFEKAAELGIGFNLGYAELVVEGGVKRRFNTSILVDKPGKIVGKYRKIHLPGHKEYEAYRPFQHLEKRYFEPGDLGFPVYDVDAAKMGMFICNDRRWPEAWRVMGLRGAEIICGGYNTPTHNPPVPQHDHLTSFHHLLSMQAGSYQNGAWSAAAGKVGMEENCMLLGHSCIVAPTGEIVALTTTLEDEVITAAVCLDRCRELREHIFNFKQHRQPQHYGLIAEL
Protein: Sirtuin 1 (E9PC49)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS
Protein: receptor protein-tyrosine kinase (EC 2.7.10.1) (B5BM28)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MYRGCRRVYGNLEITWIEANEIKKWRESTNSTVDPKNEDSPLKSINFFDNLEEIRGSLIIYRANIQKISFPRLRVIYGDEVFHDNALYIHKNDKVHEVVMRELRVIRNGSVTIQDNPKMCYIGDKIDWKELLYDPDVQKVETTNSHQHCYQNGKSMAKCHESCNDKCWGSGDNDCQRVYRSVCPKSCSQCFYSNSTSSYECCDSACLGGCTGHGPKNCIACSKYELDGICIETCPSRKIFNHKTGRLVFNPDGRYQNGNHCVKECPPELLIENDVCVRHCSDGHHYDATKDVRECEKCRSSSCPKICTVDGHLTNETLKNLEGCEQIDGHLIIEHAFTYEQLKVLETVKIVSEYITIVQQNFYDLKFLKNLQIIEGRKLHNVRWALAIYQCDDLEELSLNSLKLIKTGAVLIMKNHRLCYVSKIDWSSIITSKGKDNKPSLAIAENRDSKLCETEQRVCDKNCNKRGCWGKEPEDCLECKTWKSVGTCVEKCDTKGFLRNQTSMKCERCSPECETCNGLGELDCLTCRHKTLYNSDFGNRMECVHDCPVSHFPTQKNVCEKCHPTCYDNGCTGPDSNLGYGGCKQCKYAVKYENDTIFCLQSSGMNNVCVENDLPNYYISTYDTEGVIETHCEKCSISCKTCSSAGRNVVQNKCVCKHVEYQPNPSERICMDQCPVNSFMVPDTNNTVCKKCHHECDQNYHCANGQSTGCQKCKNFTVFKGDIAQCVSECPKNLPFSNPANGECLDYDIASRQRKTRMVIIGSVLFGFAVMFLFILLVYWRCQRIGKKLKIAEMVDMPELTPIDASVRPNMSRICLIPSSELQTKLDKKLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTDQSQTDEMLEEATNMFRLRHDNLLKIIGFCMHDDGLKIVTIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQRVVHRDLATRNVLVKKFNHVEITDFGLSKILKHDADSITIKSGKVAIKWLAIEIFSKHCYTHASDVWAFGVTCWEIITFGQSPYQGMSTDSIHNFLKDGNRLSQPPNCSQDLYQELLRCWMADPKSRPGFEILYERFKEFCKVPQLFLENSNKISESDLSAEERFQTERIREMFDGNIDPQMYFDQGSLPSMPSSPTSMATFTIPHGDLMNRMQSVNSSRYKTEPFDYGSTAQEDNSYLIPKTKEVQQSAVLYTAVTNEDGQTELSPSNGDYYNQPNTPSSSSGYYNEPHLKTKKPETSEEAEAVQYENEEVSQKETCL
Protein: Oxytocin receptor (OT-R) (P97926)
Organism: Mus musculus (Mouse)
Function: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Oxytocin-neurophysin 1
- Guanine nucleotide-binding protein G
- Voltage-dependent L-type calcium channel subunit alpha-1S
- Voltage-dependent L-type calcium channel subunit alpha-1C
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Voltage-dependent calcium channel gamma-2 subunit
- Guanine nucleotide-binding protein G
- Voltage-dependent calcium channel subunit alpha-2/delta-1
Sequence:
MEGTPAANWSIELDLGSGVPPGAEGNLTAGPPRRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASVPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGSDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSARYLKGSRPGETSISKKSNSSTFVLSRRSSSQRSCSQPSSA
Protein: L-arabinitol 4-dehydrogenase (LAD) (EC 1.1.1.12) (Q96V44)
Organism: Hypocrea jecorina (Trichoderma reesei)
Function: Catalyzes the NAD-dependent oxidation of L-arabinitol to L-xylulose in the fungal L-arabinose catabolic pathway. L-arabinose catabolism is important for using plant material as a carbon source. Can partially compensate for xylitol dehydrogenase in xdh1 mutants. Also oxidizes galactitol to L-xylo-3-hexulose as an alternative to the standard Leloir pathway for D-galactose metabolism. NADP cannot act as a cosubstrate.
Interaction partners:
Sequence:
MSPSAVDDAPKATGAAISVKPNIGVFTNPKHDLWISEAEPSADAVKSGADLKPGEVTIAVRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGEVIAVHPTVSSLQIGDRVAIEPNIICNACEPCLTGRYNGCEKVEFLSTPPVPGLLRRYVNHPAVWCHKIGNMSWENGALLEPLSVALAGMQRAKVQLGDPVLVCGAGPIGLVSMLCAAAAGACPLVITDISESRLAFAKEICPRVTTHRIEIGKSAEETAKSIVSSFGGVEPAVTLECTGVESSIAAAIWASKFGGKVFVIGVGKNEISIPFMRASVREVDIQLQYRYSNTWPRAIRLIESGVIDLSKFVTHRFPLEDAVKAFETSADPKSGAIKVMIQSLD
Protein: Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.-) (Q9ALW2)
Organism: Streptococcus agalactiae
Interaction partners:
Sequence:
MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIAK