wanglab/gogpt-training-data huggingface dataset:
Protein: Protein disulfide-isomerase like 2-2 (AtPDIL2-2) (EC 5.3.4.1) (Protein disulfide-isomerase 10) (PDI10) (Protein disulfide-isomerase like 5-1) (AtPDIL5-1) (Q9MAU6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000305}.
Interaction partners:
- Endoplasmic reticulum oxidoreductin-2
- Endoplasmic reticulum oxidoreductin-1
- Uncharacterized mitochondrial protein AtMg00600
- AT3g07170/T1B9_17
- Uncharacterized protein At2g34160
- Eukaryotic translation initiation factor 4E-1
- DEAD-box ATP-dependent RNA helicase 46
- F13M7.16 protein
- 5'-adenylylsulfate reductase-like 5
- Calreticulin-1
Sequence:
MERKMYKSTVFPICCLLFALFDRGNALYGSSSPVLQLTPSNFKSKVLNSNGVVLVEFFAPWCGHCQSLTPTWEKVASTLKGIATVAAIDADAHKSVSQDYGVRGFPTIKVFVPGKPPIDYQGARDAKSISQFAIKQIKALLKDRLDGKTSGTKNGGGSSEKKKSEPSASVELNSSNFDELVTESKELWIVEFFAPWCGHCKKLAPEWKKAANNLKGKVKLGHVNCDAEQSIKSRFKVQGFPTILVFGSDKSSPVPYEGARSASAIESFALEQLESNAGPAEVTELTGPDVMEDKCGSAAICFVSFLPDILDSKAEGRNKYLEMLLSVADKFKKDPYGFVWVAAGKQPDLEKRVGVGGYGYPAMVALNAKKGAYAPLKSGFEVKHLKDFVKEAAKGGKGNLPIDGTMEIVKTEAWDGKDGEVVDADEFSLEDLMGNDDEASTESKDDL
Protein: Large ribosomal subunit protein uL14x/uL14z/uL14y (60S ribosomal protein L23) (Protein EMBRYO DEFECTIVE 2171) (P49690)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL6z/uL6y
- Large ribosomal subunit protein uL22y
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein uL3z
- Large ribosomal subunit protein eL28z
- Small ribosomal subunit protein uS17z
- Large ribosomal subunit protein eL32z
- Small ribosomal subunit protein eS30z/eS30y/eS30x
Sequence:
MSKRGRGGTSGNKFRMSLGLPVAATVNCADNTGAKNLYIISVKGIKGRLNRLPSACVGDMVMATVKKGKPDLRKKVLPAVIVRQRKPWRRKDGVFMYFEDNAGVIVNPKGEMKGSAITGPIGKECADLWPRIASAANAIV
Protein: Deoxycytidine kinase 1 (XldCK) (EC 2.7.1.74) (Deoxyadenosine kinase 1) (EC 2.7.1.76) (Deoxyguanosine kinase 1) (EC 2.7.1.113) (A0A1L8HV70)
Organism: Xenopus laevis (African clawed frog)
Function: Phosphorylates the deoxyribonucleosides deoxyadenosine, deoxycytidine and deoxyguanosine with highest activity against deoxycytidine followed by deadenosine and deoxyguanosine. Shows only very minor activity against deoxyuridine and deoxythymidine.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P27707}.
Interaction partners:
- Cytidine deaminase
- Cytidine deaminase
- Deoxycytidylate deaminase
- UMP-CMP kinase 2, mitochondrial
- Adenylosuccinate lyase
- UMP-CMP kinase
- AMP deaminase
- GTP:AMP phosphotransferase AK3, mitochondrial
- dCTP pyrophosphatase 1
- AMP deaminase
Sequence:
MATPPKRICIDVPASPSGNKCKVKRISIEGNIAAGKSTFVNILKKANEEWDVVPEPIARWCNIQSCKDEFEELTTSQKSGGNLLQMMYEKPERWSFTFQSYACLSRIRAQLKALGGKLKEAENPVLFFERSVYSDRYIFASNLYEAECMNETEWTVYQDWHDWMNSQFGADLELDGIIYLRAIPEKCLNRVYTRGREEEQGIPMEYLEKLHYKHETWLHHRTLRTDFEYLQEIPILTLDVNEDFRDNKQKQESLIEKVKEFLSTL
Protein: Zeamatin (P33679)
Organism: Zea mays (Maize)
Function: Has antifungal activity. Inhibits Candida albicans and Trichoderma reesei; marginal inhibition observed against Alternaria solani and Neurospora crassa.
Interaction partners:
Sequence:
MAGSVAIVGIFVALLAVAGEAAVFTVVNQCPFTVWAASVPVGGGRQLNRGESWRITAPAGTTAARIWARTGCKFDASGRGSCRTGDCGGVLQCTGYGRAPNTLAEYALKQFNNLDFFDISLIDGFNVPMSFLPDGGSGCSRGPRCAVDVNARCPAELRQDGVCNNACPVFKKDEYCCVGSAANDCHPTNYSRYFKGQCPDAYSYPKDDATSTFTCPAGTNYKVVFCP
Protein: Zinc finger CCCH domain protein (Q8RWV9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Histone deacetylase 6
- Histone deacetylase 19
- Paired amphipathic helix protein Sin3-like 2
- Paired amphipathic helix protein Sin3-like 1
- Paired amphipathic helix protein Sin3-like 3
- Histone-binding protein MSI1
- Histone deacetylase HDT3
- Histone deacetylase 9
Sequence:
MSGVPKRSHEEGVTHPSSSSSVAKYPHEDSGSYPKSPHQPVTPPPAQVHHNHQQPHQHPQSQSQSQPQPHLQALPHPHSHSHSHSPLAAAASASAPYEVESRTVVKVARSEPRDGERRSPLPLVYRSPSLPTTVSSSDPHLTHAPVPMEPRDGAKDGREIRVESRENRSDGREIYGETKREIQGPKGDRDVKFERSVDDFSGKGNTGSYTRNDGREMYGETKREIQGPKSDRDAKFERPGDDFSGKSNAGSYTRDTKFDRENQNYNEQKGEIKMEKEGHAHLAWKEQKDYHRGKRVAEGSTANVDPWVVSRGNPQGPTEVGPKDLSAPVEGSHLEGRETVGENKVDAKNEDRFKEKDKKRKELKHREWGDRDKDRNDRRVSVLVGSVMSEPKEIGREERESDRWERERMEQKDRERNKEKDKDHIKREPRTGAEKEISQNEKELGEASAKPSEQEYVAPEQKKQNEPDNCEKDERETKEKRRERDGDSEAERAEKRSRISEKESEDGCLEGEGATEREKDAFNYGVQQRKRALRPRGSPQTTNRDNVRSRSQDNEGVQGKSEVSIVVYKVGECMQELIKLWKEYDLSHPDKSGDFANNGPTLEVRIPAEHVTATNRQVRGGQLWGTDIYTDDSDLVAVLMHTGYCRPTASPPPPTMQELRTTIRVLPSQDYYTSKLRNNVRSRAWGAGIGCSYRVERCYILKKGGGTIELEPSLTHSSTVEPTLAPMAVERSMTTRAAASNALRQQRFVREVTIQYNLCNEPWIKYSISIVADKGLKKPLFTSARLKKGEVLYLETHSCRYELCFAGEKTIKAIQASQQQSSHEAMETDNNNNKSQNHLTNGDKTDSDNSLIDVFRWSRCKKPLPQKLMRSIGFPLPADHIEVLEENLDWEDVQWSQTGVWIAGKEYTLARVHFLSPN
Protein: Swi5-dependent recombination DNA repair protein 1 homolog (Meiosis protein 5 homolog) (Q8BP27)
Organism: Mus musculus (Mouse)
Function: Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1.
Subcellular location: Nucleus {ECO:0000269|PubMed:20976249}.
Interaction partners:
- DNA repair protein SWI5 homolog
- DNA repair protein XRCC2
- DNA repair protein XRCC3
- DNA repair protein RAD51 homolog 3
- DNA repair protein RAD51 homolog 4
- DNA repair protein RAD51 homolog 2
- DNA repair protein RAD51 homolog 1
Sequence:
MAEEGNQEFTSKMENSSDSASTSPDAPQPSENPPSPPTSPAAPQTSENPPSPPTSPAVPQTRENPPSPPTSPAAPQPRENPPSPPTSPAAPQPRENPPSPPTSPAAPQPRENPPSPHSNSSGKQPLSGTPKERLKKARSSSHSFCSVVKRMKVENDENNETLSEPGESSKEENCSKAQESLKNKDSEPGEKSSEEKNTCESKSSDTGSSNALPKESENAIIREKLKQEKIRLIRQVEEKEDLLRRLKLVKMYRIKNDVTELENLIKKWRKCGQRLLCELQSIMSEDEDEKLTLTELIDFYGIDDNLLHYNRSEEEFTGV
Protein: CRAL-TRIO domain-containing protein YKL091C (P33324)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
Sequence:
MTTSILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKNYKERLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGISLSNAYHVLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFILGSSYKKELLKQIPIENLPVKYGGTSVLHNPNDKFYYSDIGPWRDPRYIGPEGEIPNIFGKFTVTS
Protein: Neuropeptide Y /peptide YY receptor Yb (Neuropeptide Y receptor Y8b) (O57463)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Peptide YY-A
- Pro-neuropeptide Y
Sequence:
MERSHLNNSSWLLEDPTCPASLSSTTFLIVAYSTMLAVGLVGNTCLVVVITRQKEMRNVTNIFIVNLSCSDILVCLVCLPVTIIYTLMDRWILGEALCKVTPFVQCMSVTVSIFSMVLIALERHQLIIHPTGWKPVVRHSYLAVAVIWIIACFISLPFLSFNILTNSPFHNLSLPFNPFSDHFICIEQWPSEGNRLTYTTTLLLCQYCLPLALILVCYFRIFLRLSRRKDMVERARGGRQKKAKGSKRVNAMLASIVAAFALCWLPLNVFNTIFDWNHEAIPVCQHDAIFSACHLTAMASTCVNPVIYGFLNNNFQKELKSLLSRCRCWGPAESYESFPLSTVSTGITKGSILSNGSASTYQPHKKNSLEQKESI
Protein: Septin (Q25AR8)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSDIEHKLQHLPPHQPPPPVPHHHQNQPTHNNTTTISSATSSINTTTTSKKPTIAAPTAPSPIKSLSDHTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGKTTLIESLFNMKLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVDYLESQFETYLQEELKPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAKSDTTCKDELLRFKAKILSELKSQKIDIYTFPTDDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQMVRARQYPWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGETGPKIIEKLAQRRLQKHREHQDEFSRRELTLREEFQKKLDVTEGDMRKVEEGLAAREREVHENYNREASKLDMEIRQLTEERMKLMTKVSKKLRK
Protein: LNR domain-containing protein (Q54MP1)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MARLQERGSVVKLIQFKLFSFLSSRFGMLFCIIGVFISFNTILQLVRLYTDNSFISSDIYNQKPTFFSQSYWEDNVGGKSYQNILCSQPIDIVYTWVNGSDPKLIKEVTELKRSKRDPLIPECQGKQTPEKDKCYRDDNTASRYVDNQELKYSLRSIEKFAPWIRHVYIVTNGQVPNWINLSNPKLSIVTHQEIFANKSHLPTFSSPSIETHLHRIPGLSKKFIYLNDDVMLGREIYPDDFVTQNGGQRVFLSWPVPNCNDGCPNNWIGDGFCDNACNVFNCEFDGGDCDNSTGTVKTRWWNRGNNGGGTTTSTTTTSNTGNLNGLTSNDRLKSYCSRGCPDSWVGDKHCDRMCKNEDCGYDAGDCGVELMFTSMKGYEINKNTSIISLPDGTRSVYFNLSTLIGEGTITDGSHDNAILVRTATISQKYKIMTLTFHRDKEFQNIAVSITYEITSKKQKSITTTTTNSTTNSTITTIDSLDKGNTNSEQEELITESIEKNFNITLSTKEESSSSSSSSISSKEKKVDLESDKTNQQTLIGTGEELSPSPTVESNKGKSNFSTKAIDQLGDEIISPPIGSIEDVEGLPPASIRDREEIITGNEQVKDPNNEKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNQNNQLTSSENKDQKDYKINKKLSKNDLDTAQQQEEQKEQEEQKENKEKMFDLADTLDKEELEKKWQEFYDSVKKSQENSNLNENENTNTNTNRGILSIEIDNSLDYNDHLQLHEEKEKEKEENENENKNEEEEKEEGNEKNYNNQNDNFKLINQNDNIILKNNKFSVNNDNEDKDEKNKDDDNIEKILKIKEIELREYQEQLTEQMEQDRKYRINKETENRMNQEGEIFPWEEFTPIDDGNQINSIKSKPMNRKPLDMFGDSLKFVNRLYSKEFGSSPRKVPAHMPHMIDVDVMYEIQAKWPAQWDATSSHSLRHPQDMQYAFSFFYYLINKKQTVDVDKLWKDWDGDRDNVLNDNELRTFSVNVYNVPLKVGQFDQIKNYFYHICIQHKLLTNVEQGIDIEATLERLNRNHSADAPDPKDREYCPITLDVIKSDNKTMEDIKKYYSKKQFYKTTLDGTDEVAFLMIDNDYNVVQSKLDGIRQRRQKFICLNDNIDHASPNNSKVVQVLHNFYDSLFALPSSFELPPGQFNNFQYIEDFKADVVEIRTKNYNSYYFMVSVSLALLFILWKCKCSTSLHKSKFKKGLPTRMSVH
Protein: Myosin VI (A0A590UKB0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAE
Protein: Putative mitochondrial transporter UCP3 (Solute carrier family 25 member 9) (Uncoupling protein-3) (UCP 3) (P56499)
Organism: Rattus norvegicus (Rat)
Function: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P56501}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Carnitine O-palmitoyltransferase 1, muscle isoform
- [Pyruvate dehydrogenase
- Peroxisome proliferator-activated receptor alpha
- Solute carrier family 2, facilitated glucose transporter member 4
- Insulin-1
- Insulin-2
- Peroxisome proliferator-activated receptor gamma
Sequence:
MVGLQPSEVPPTTVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGVQSVQYRGVLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDHSSVAIRILAGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIKEKLLDSHLFTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNAPPGRYRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQLKRALMKVQVLRESPF
Protein: Ino eighty subunit 3 (Q12345)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Ino eighty subunit 1
- Ino eighty subunit 4
- Ino eighty subunit 5
- Non-histone protein 10
- RuvB-like protein 1
- Chromatin-remodeling complex subunit IES6
- RuvB-like protein 2
- Transcription initiation factor TFIID subunit 14
- Chromatin-remodeling ATPase INO80
- Actin-related protein 4
Sequence:
MKFEDLLATNKQVQFAHAATQHYKSVKTPDFLEKDPHHKKFHNADGLNQQGSSTPSTATDANAASTASTHTNTTTFKRHIVAVDDISKMNYEMIKNSPGNVITNANQDEIDISTLKTRLYKDNLYAMNDNFLQAVNDQIVTLNAAEQDQETEDPDLSDDEKIDILTKIQENLLEEYQKLSQKERKWFILKELLLDANVELDLFSNRGRKASHPIAFGAVAIPTNVNANSLAFNRTKRRKINKNGLLENIL
Protein: Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50) (Q9UKX7)
Organism: Homo sapiens (Human)
Function: Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity). This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity).
Subcellular location: Nucleus, nuclear pore complex {ECO:0000269|PubMed:12802065}. Nucleus membrane {ECO:0000250|UniProtKB:O08587}; Peripheral membrane protein {ECO:0000250|UniProtKB:O08587}; Nucleoplasmic side {ECO:0000250|UniProtKB:O08587}. Note=Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity). Dissociates from the NPC structure early during prophase of mitosis (PubMed:12802065). Associates with the newly formed nuclear membrane during telophase (PubMed:12802065). In the testis, the localization changes during germ cell differentiation from the nuclear surface in spermatocytes to the whole nucleus (interior) in spermatids and back to the nuclear surface in spermatozoa (By similarity). {ECO:0000250|UniProtKB:O08587, ECO:0000269|PubMed:12802065}.
Interaction partners:
- Nuclear pore complex protein Nup153
- Importin subunit alpha-5
- Nucleoporin Nup43
- Nucleoprotein TPR
- Nuclear pore complex protein Nup85
- Nuclear pore complex protein Nup107
- Nuclear pore complex protein Nup88
- Nuclear pore complex protein Nup93
- Nuclear pore complex protein Nup155
- Nucleoporin NUP35
Sequence:
MAKRNAEKELTDRNWDQEDEAEEVGTFSMASEEVLKNRAIKKAKRRNVGFESDTGGAFKGFKGLVVPSGGGRFSGFGSGAGGKPLEGLSNGNNITSAPPFASAKAAADPKVAFGSLAANGPTTLVDKVSNPKTNGDSQQPSSSGLASSKACVGNAYHKQLAALNCSVRDWIVKHVNTNPLCDLTPIFKDYEKYLANIEQQHGNSGRNSESESNKVAAETQSPSLFGSTKLQQESTFLFHGNKTEDTPDKKMEVASEKKTDPSSLGATSASFNFGKKVDSSVLGSLSSVPLTGFSFSPGNSSLFGKDTTQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEEDAFYSKKCKLFYKKDNEFKEKGIGTLHLKPTANQKTQLLVRADTNLGNILLNVLIPPNMPCTRTGKNNVLIVCVPNPPIDEKNATMPVTMLIRVKTSEDADELHKILLEKKDA
Protein: Serum amyloid A-2 protein (SAA2) [Cleaved into: Amyloid A2 protein (AA2)] (P0DJI9)
Organism: Homo sapiens (Human)
Function: Major acute phase reactant.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P0DJI8}.
Interaction partners:
- Serum amyloid A-1 protein
- Serum amyloid A-4 protein
- Apolipoprotein A-I
- Interleukin-6
- Serum amyloid P-component
- Apolipoprotein C-III
- Phospholipid transfer protein
- C-reactive protein
- Apolipoprotein F
- Apolipoprotein A-II
Sequence:
MKLLTGLVFCSLVLSVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISNARENIQRLTGRGAEDSLADQAANKWGRSGRDPNHFRPAGLPEKY
Protein: High Incidence of Males (Increased X chromosome loss) (Q22360)
Organism: Caenorhabditis elegans
Interaction partners:
- X chromosome NonDisjunction factor
- Double-Strand Break factor
- Meiotic recombination protein spo-11
- Double-Strand Break factor
- DNA repair protein RAD51 homolog
- C2H2-type domain-containing protein
- C2H2-type domain-containing protein
Sequence:
MAKRPSTSKNPAEDDELIIDECRRKLDDDESNDVGAYFEDDNQQGTSYRTPFMPSHLGLIQDQSPDLTMKDLFNRKRSRPQSTGFIDHSQARYYDRYKQQEYTRRNDFMKYCHVCRKKTVGKLRVLPGDLRMRKVWILRSNLDEERSAELWLREMACEGSHGGEFCEAHFPAGSQHMKGNQLIPLDVRPEEGRHSVVEDIQFDFDAIHLQCVFCGRDGPLATMLPFIRNRAKRLRWIEQLASGNETYKNRLLHALRGGVTQFLCDYHISDSSFEINGFGEWRLLKNALPDPRLVASDKRGERKYLVDKCRDEMFWERAMWKSADLLSQNGTADDEDIIVGDDIRQFLTNSVPSEAEQVLHPILQIKQNVEKKLNEADLQPGTSGTSGESNATADNLKIGISEEGVEYSDDSDEENELIEKMGDIPYSKRLCQVCSAVEPIGNEFPNNFPYKFSIRTWPFDECRHKKWLEIMDWPPEFEESMKTLWQKRKTEGALSDSYHFCPINVCQSHLDFRQLPERMEEWHQTFCLLCDTCMSDKSFLVGIPHNFETRTKWANSLFPVKEGNKFQLKKISWLRRRFLRSKPTRYRICVYHFNRKAFQVNQDDKIVLDAEALPLPIDSDDFDLTPRGPNSVCKCVLCDDWKKVEDMVPFRAPHSEAERSFLIDIVIHSDKMTIKKALASLAKTNRPALICNIHFPDGIDPFSIIAERRLMYGVQSECVLCAHANDCTAMIPFPGPDDEKLRTKWINSMCREPWIYRYLSTRLEKPGRHYLCASHFNRNSLRYHAGLGLWRRAAACPVLACTTDEERQEVWDLSKSQPLYHPLILETFDDNGSGRLDYDDVLNFLGTERMRQIETELNFHGRNDSLLRRENRKKNTGRSFYADMPNIYEHGELQEVEDQMEGEEEEVVQEECIIYEEEHHLDEAEELEVIEEEEVVEEIVEQVVDDGVVVGEEM
Protein: Probable arabinosyltransferase B (EC 2.4.2.-) (P9WNL7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable arabinosyltransferase A
- Meromycolate extension acyl carrier protein
- Galactan 5-O-arabinofuranosyltransferase
- Enoyl-[acyl-carrier-protein] reductase
- Small ribosomal subunit protein uS12
- Nicotinamidase/pyrazinamidase
- DNA-directed RNA polymerase subunit beta
- DNA gyrase subunit A
- Catalase-peroxidase
- DNA gyrase subunit B
Sequence:
MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFTATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFANFVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLDQLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVSPMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRRKRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCWATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVASMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAEAIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDWIAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGITDLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP
Protein: Transcriptional repressor Mce3R (TetR family transcriptional regulator) (P95251)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Mce3R represses the transcription of mce3 operon and down-regulates its own expression, but does not affect the transcription of mce1, mce2 and mce4 operons.
Interaction partners:
- Possible transcriptional regulatory protein
- Transcriptional regulatory protein EmbR
- Mce-family protein Mce3A
- Possible transcriptional regulatory protein
- Uncharacterized HTH-type transcriptional regulator Rv2282c
- Possible transcriptional regulatory protein NadR
- Transcriptional regulatory protein
- HTH-type transcriptional regulator Rv1931c
- HTH-type transcriptional regulator VirS
- Probable transcriptional regulatory protein
Sequence:
MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA
Protein: Mitochondrial fission process protein 1 (Mitochondrial 18 kDa protein) (MTP18) (Q9CRB8)
Organism: Mus musculus (Mouse)
Function: Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function leads to apoptosis (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Dynamin-1-like protein
Sequence:
MSEQQRQGAERDLYRDTWVRYLGYANEVGEAFRSLVPAAVVWLSYGVSSSYVLADAIDKGKKAGEVPSPEAGRNTRMALAVVDTFVWQSLASVAIPGFTINRLCAASLYVLGTMTHWPPTVRKWTTTTLGLLAIPVIIHPIDRSVDFLLDSSLRKLYPSVEKPSTP
Protein: Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma) (Q9CWZ7)
Organism: Mus musculus (Mouse)
Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular location: Membrane {ECO:0000250|UniProtKB:P81127}; Peripheral membrane protein {ECO:0000250|UniProtKB:P81127}. Golgi apparatus {ECO:0000269|PubMed:9705316}.
Interaction partners:
- Vesicle-fusing ATPase
- Beta-soluble NSF attachment protein
- Alpha-soluble NSF attachment protein
- Syntaxin-8
- Golgi SNAP receptor complex member 1
- Syntaxin-7
- Vesicle-associated membrane protein 4
- Syntaxin-12
- Neuroblastoma amplified sequence
- Syntaxin-6
Sequence:
MAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKEKNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLEGYDQQDQDQVSEVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKSPATPQAKPDGAAGMAAEEEEDEYSGGLC
Protein: tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOP2/Sun domain family member 2 ortholog) (Q9W4M9)
Organism: Drosophila melanogaster (Fruit fly)
Function: RNA methyltransferase that methylates tRNAs. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Required for short-term memory.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q08J23}.
Interaction partners:
- tRNA
- Pseudouridylate synthase 7 homolog
- 28S rRNA
- Nucleolar complex protein 2
- Protein penguin
- Ribosome biogenesis protein BRX1 homolog
- Nucleolar GTP-binding protein 1
- LD24793p
- RRM domain-containing protein
- Nucleolar protein 58
Sequence:
MGRNQKQNFFAARKRQKRENGPKRTDRQAQPYEEIKRDNAFFIKYYQLQKICATDEEWTQFLASIRDNLPTTFRVTGFKDEAKALLSIIETQLFTEYVRAVAELHQKAPEDVERPLCLPWYPNGLAYQLHLTRKDIRRSEPLYRLHNFLIVETTAGGISRQEAVSMIPPIVLDVRPTDKVLDMCAAPGSKTAQLIEALHAAPEEHKIPPGFVLANDVDNNRCYMLVHQAKRLNSPCLLVTNHDSSVFPNLVTTKPDGSKAILKFDKILCDVPCSGDGTLRKNPDIWLKWNLAQAYNLHGIQYRIVRRGAEMLEVGGRLVYSTCSLNPIENEAVLQRIIKDADGALELVDAGHLVPGLKYKPGMTDWKLATKEVDQIFTRFEEVPESLHTIIRPGMFPLPADEMAKIGLEKCLRVLPHLQDSGGFFVAVLEKRRQLSFEKNDVVELVKLNETAKQPAAEPQVDADGKPIEEKSVPWGPQRKKRRLHGYKEDPYVFFGENDPDYQAIKEFYQLDESLSQRCLLTRCVTEKKKNIYYCSEPIRDLVLNNENNIKIINTGVKTFVRCENRHTVHPFRLAQEGLQTSNAFMGASRRIQVEREDLVMMLNCTDPTQPPSTHELKKETQERCKELGVGSCILKYVDQRFTLYTVGWRGTSSLRAYVQKDETIHILRLLGADLSKFETNKYEDARVAAAAAADAEVGKSAEAEADSSGDGDATESTFSGSGAIDVTVAAETTGTPMDTEVVATS
Protein: 5'-deoxynucleotidase HDDC2 (EC 3.1.3.89) (HD domain-containing protein 2) (Q3SXD3)
Organism: Mus musculus (Mouse)
Function: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
Interaction partners:
Sequence:
MALASSGSGAGLLRFLRLVGQLKRVPRTGWVYRNVEKPESVSDHMYRMAVMAMVTRDDRLNKDRCIRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWEEYETQSSEEAKFVKQLDQCEMILQASEYEDLENKPGRLQDFYDSTAGKFSHPEIVQLVSELETERNASMATASAEPGS
Protein: Syntaxin-51 (AtSYP51) (Q9SA23)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Vesicle trafficking protein that functions in the secretory pathway.
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein.
Interaction partners:
- Vesicle transport v-SNARE 11
- Syntaxin-22
- Vesicle-associated membrane protein 727
- Vesicle transport v-SNARE 12
- Vesicle transport v-SNARE 13
- VAMP-like protein YKT62
- Tlg2p-like protein a
- Syntaxin-21
- VAMP-like protein YKT61
- Putative syntaxin-24
Sequence:
MASSSDSWMRAYNEALKLSEEINGMISERSSSAVTGPDAQRRASAIRRKITIFGNKLDSLQSLLAEIHGKPISEKEMNRRKDMVGNLRSKANQMANALNMSNFANRDSLLGPDIKPDDSMSRVTGMDNQGIVGYQRQVMREQDEGLEQLEGTVMSTKHIALAVSEELDLQTRLIDDLDYHVDVTDSRLRRVQKSLAVMNKNMRSGCSCMSMLLSVLGIVGLAVVIWMLVKYM