wanglab/gogpt-training-data huggingface dataset:
Protein: Cilia- and flagella-associated protein HOATZ (Q80Y73)
Organism: Mus musculus (Mouse)
Function: Required for motile ciliogenesis and flagellar genesis by mediating the maturation of the glycolytic enzyme ENO4.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:32248064}. Cell projection, cilium {ECO:0000269|PubMed:32248064}.
Interaction partners:
- Transcription initiation factor IIB
- Transcription initiation factor TFIID subunit 1
- B-TFIID TATA-box binding protein associated factor 1
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 13
- Dr1-associated corepressor
- Transcription factor TFIIIB component B'' homolog
- Transcription initiation factor IIA subunit 2
Sequence:
METGPRGCPSGRKESQEICSPGLLVFTGCSEQDANLAKQFWLGASMYPTTESQLVLTRGSSQRLPVARNSKVVLREKSSVQPFPFDQDKDAIIFAKAQRIQESEERAKYLQKAKTRDEILQLLRKQREERISKELISLPYKPKDKVPKSKEVLSESGLRDQEEVKALE
Protein: Emb|CAB62340.1 (Q9FKS6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDQDHELWRTLRCAGKAQDKTSVDTLMLKYRPIAPKPTTTGQPLVGDTSSTRRTKRKYVRVSKNNKATCRSKTNGFRSSSTDPENGREDIVTLQLLPERSTPLSLDHNNLDPTVETINGDETCNTDTWLKFNGGDDALQQVPVETWVTVESVNSGLVSHAVGLTDEELTYALDKDTCPGFISDGSNRVVMVNEAYRRIVTGDGGFGREVIVWLVVDQTATFCDYRTFTCKVRMEYTWRETKYTKTLPCDVWKMEFGGFAWRLDTTAALTLWL
Protein: 1,3-beta-glucan synthase (EC 2.4.1.34) (1,3-beta-D-glucan-UDP glucosyltransferase) (Q6FMZ3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- 1,3-beta-glucan synthase
- UTP--glucose-1-phosphate uridylyltransferase
- 1,3-beta-glucan synthase
- GTP-binding protein RHO1
- glucan 1,3-beta-glucosidase
- glucan 1,3-beta-glucosidase
- Candida glabrata strain CBS138 chromosome M complete sequence
- Glycogen [starch] synthase
- Glycogen [starch] synthase
- glucan 1,3-beta-glucosidase
Sequence:
MSYDQGGNGNWQNTDPNGNYYYNGAENNEFYDQDYASQQPEQQQGGEGYYDEYGQPNYNYMNDPQQGQMPQQQPGGYENDGYYDSYYNNQMNAGVGNGLGPDQTNFSDFSSYGPPPFQNNQANYTPSQLSYSNNGMGSNGMNMSGSSTPVYGNYDPNAIAMTLPNDPYPAWTADPQSPVSIEQIEDVFIDLTNKFGFQRDSMRNIFDLFMTLLDSRTSRMSPDQALLSVHADYIGGDTANYKKWYFAAQLDMDDEVGFRNMNLGKLSRKARKAKKKNKKAMEEANPEDAAEVLNKIEGDNSLEASDFRWKTKMNMLTPIERVRQVALYMLIWGEANQVRFTSECLCFIYKCASDYLESPLCQQRTEPIPEGDYLNRVITPIYQFIRNQVYEIVDGRYVKREKDHNKIIGYDDVNQLFWYPEGITKIVLEDGTKLTDIPSEERYLRLGEVAWNDVFFKTYKETRTWLHLVTNFNRIWIMHVSVYWMYVAYNSPTFYTHNYQQLVNNQPVPAYRWASAALAGTVASAIQLFATVCEWWFVPRKWAGAQHLSRRFWFLCGILGVNLGPLIFVFAYEKDTVQSKAGHAVAAVTFFIAVATVLFFSIMPLGGLFTSYMQKSSRRYVASQTFTASFAPLQGLDRWLSYLVWVTVFAAKYSESYFFLILSLRDPIRILSTTTMRCTGEYWWGSKLCRHQSKIVLGFMIATDFILFFLDTYLWYIVVNTVFSVGKSFYLGISILTPWRNIFTRLPKRIYSKILATTDMEIKYKPKVLISQIWNAIIISMYREHLLAIDHVQKLLYHQVPSEIEGKRTLRAPTFFVSQDDNNFETEFFPRNSEAERRISFFAQSLATPMPEPLPVDNMPTFTVLTPHYSERILLSLREIIREDDQFSRVTLLEYLKQLHPVEWECFVKDTKILAEETAAYENEETQDPEKSDALKTQIDDLPFYCIGFKSAAPEYTLRTRIWASLRSQTLYRTVSGFMNYARAIKLLYRVENPEIVQMFGGNAEGLERELEKMARRKFKFLVSMQRLAKFKPHELENTEFLLRAYPDLQIAYLDEEPPLNEGEEPRIYSALIDGHCEMLENGRRRPKFRVQLSGNPILGDGKSDNQNHALIFYRGEYIQLIDANQDNYLEECLKIRSVLAEFEELNAEPVYPYTPGVKYEDQKTNHPVAIVGAREYIFSENSGVLGDVAAGKEQTFGTLFARTLAQIGGKLHYGHPDFINATFMTTRSGLSKAQKGLHLNEDIYAGMNALLRGGRIKHCEYYQCGKGRDLGFGTILNFTTKIGAGMGEQMLSREYYYLGTQLPVDRFLTFYYAHPGFHLNNLFIQLSLQMFMLTLVNLHALAHESILCIYDRNKPKTDVLYPIGCYNFSPAIDWIRRYTLSIFIVFWIAFVPIVVQELIERGLWKATQRFFRHILSLSPMFEVFAGQIYSAALLSDMTVGGARYISTGRGFATSRIPFSILYSRFASSAIYMGARSMLMLLFGTVAHWQAPLLWFWASLSALLFSPFIFNPHQFSWEDFFLDYRDYIRWLSRGNNKYHKNSWIGYVRMARSRITGFKRKLIGDDSEKAAGDANRAHRTNLILAELIPTAINAGSCFIGFTFINAQTGVKATDDDRVNSVLRVVLCTLGPIAVDVGVLFFCLGMSCCSGPLFGMCCKKTGAVMAAVAHGVSVVIHIGFFIVMWVLEGFNFTRMLVGVATVIQCQRFIFQLMTILLLTREFKNDHANTAFWTGKWYGSGFGYMAWTQPMRELTAKVIEMSEFAADFVLGHVILFAQFPVLCIPAIDKFHSIMLFWLKPSRHIRPPIYSLKQSRLRKRMVKRYLTLYIIIFLVFAGAIVGPAVAASHVPQDIGHTLTGPFHNIVQPRNKSNNDTGLQISTYSNHYYTHTPSLKTWSTIK
Protein: FI02050p (Neither inactivation nor afterpotential D, isoform A) (Q8INY3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
- Carotenoid isomerooxygenase
- Retinol-binding protein pinta
- Neither inactivation nor afterpotential protein G
Sequence:
MCCSCCGVTQQKAWVFGLGTFFAVSGLLAIICWPGFIDSGIMKALPLTPTSKTFEKWEELPIPVYVYMYLWNWTNAADVQANGVKPIFAQLGPYVYREERKKMDLEWHDNGTVTFNPRRTWFWEEELSGGKQTDLITAPHLPSLAASNQMRNSNVFLKFMFNEALNANGGHLFVTHTAAEWLFESFYDEFLHYAMTLNNPLVPKIESDHFAWFLNRNGSKDFEGPFTVHTGVGDIKEMGEIKYWKGQNHTGWYDGECGRLNGSTTDLFVPDEPKEKALTIFIPDTCRIINLEFTGQSETIQGITGWKYEITPNTFDNGQINGNAKCWCPLERQPDNCPATGATDLGPCADGVPMYLSADHFMYADESYGSTISGYNPNYDQNNFYIIMERKMGVPLKVNANVMITLYIEPDSVIDILKGLPSFYAPLFTTASRAEIDEALASELRLALNLPAIGRYTGVGFLCLGCILIAVGILLTIKRKWYGQAELDKLALKDNEETPYEPEVPANVVERNF
Protein: IP01291p (Testis-specifically expressed bromodomain containing protein-3) (Q9W1S2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- IP14655p
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 7
Sequence:
MAAKQETERSSPEINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRHRLNTGCYLSAADFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQVQLYICSSGSKVRAEEESSSDESDSSSPEDEVNGSEVSPSIMGAPPSCTPTTECTPTPDWTPPATLETSEQQEPFTTEEDLDLHAKIQQLDGEVLLHVIHFIQRMEGAEYCNKELEFDICKLKVHTKRGIRDYLASKGFTGKRVARTKPKYN
Protein: RARA protein (Retinoic acid nuclear receptor alpha variant 1) (Retinoic acid receptor, alpha, isoform CRA_c) (cDNA, FLJ92939, Homo sapiens retinoic acid receptor, alpha (RARA), mRNA) (Q6I9R7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
Protein: Rabphilin-1 (P41885)
Organism: Caenorhabditis elegans
Function: Rab-3 effector.
Subcellular location: Synapse {ECO:0000250}.
Interaction partners:
- Ras-related protein Rab-3
- small monomeric GTPase
- Protein lin-52
- Methyltransferase domain-containing protein
- Mitochondrial Ribosomal Protein, Large
Sequence:
MTKSTKLRHCKQKKKKPEKTPKGNPPILITEKSIEDAATTTSTTDALLGSPEGSRSKSRKLKLCCCTAQAATLSPLDPTSYGGIASTSAHNGMVGGLSRDSRAASRTSKRGSSKSLNRPQIDADEPSTSGTNPDRRPSTHFVLDLPVVSTRLRKLSEAFFNAQHGDKIDLMNDWEIGGTQNKWVCPSDRHLHLRAQLKSGWSVRTATARSPTNSKAQTGSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRLEKMRRRATGNGVTHCLLCHTEFGLLASKSYAAMCVDCRKYVCQRNCGVETTDVNQTTGKVETVFLCKICSEAREVLWKKSGAWFYKEMPEFQRPDDRLPYYVPVTTNGTLPNASSAATPLSGTPGGAGPQPMTMPSTSSCQMTTPKWASPGVCNSPGLQMNGGPTSPLPNGTRRNTGHGGIEFPSSSRPSICSVLQAIEPLDRSKSPRPRIQPRWVNEKVMSSMSVDDEEKAASSSDGESFVQSGVPRRALNNKTPVGSTSATTSPAPPPTSTTPTSRREANMERFSRHTHAHANRLYSTDDDDDSSPESRPSTRSTSPRHSLATPSSYAHDTCHDTSLPDADTRSIDSGVVQSDHSNPQQSGLTCSSSSLTPLQQQASHDHHSGGGTPRRISNPDRTTSRVAQSASGTSLVTPPPPISSRTSPDNCNSSPLNVMEHKSSSASTASSGGNRRVGSAEPVLNNHHAMHNNQNHNDINKKLISQTSRAESPLAASSSFLSSPDDDTKQKNRRRDGVGRVNSLQLRTSLDDVAPPVAPISKMNGHIVSSEPTSSTTSNQNHTSVPIPTVPVVPEEEEEKAITASTESASEPGSLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHDLGKHDDYIGGILLSTSAKDERGRQWIKCIENPGTLVEAWHRLELDS
Protein: LHFPL tetraspan subfamily member 5 protein (Lipoma HMGIC fusion partner-like 5 protein) (Tetraspan membrane protein of hair cell stereocilia) (Q4KL25)
Organism: Mus musculus (Mouse)
Function: In the inner ear, may be a component of the hair cell's mechanotransduction machinery that functionally couples PCDH15 to the transduction channel. Regulates transducer channel conductance and is required for fast channel adaptation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:23217710}; Multi-pass membrane protein {ECO:0000255}. Note=Efficient localization to the plasma membrane requires the presence of PCDH15. {ECO:0000269|PubMed:23217710}.
Interaction partners:
- Protocadherin-15
- Transmembrane inner ear expressed protein
- Transmembrane channel-like protein 1
- Calcium and integrin-binding family member 2
- Transmembrane channel-like protein 2
- Harmonin
- Cadherin-23
- Stereocilin
Sequence:
MVKLLPAQEAAKIYHTNYVRNSRAVGVMWGTLTICFSVLVMALFIQPYWIGDSVSTPQAGYFGLFSYCVGNVLSSELICKGGPLDFSSIPSRAFKTAMFFVALAMFLIIGSIICFSLFFVCNTATVYKICAWMQLAAATGLMIGCLVYPDGWDSSEVRRMCGEQTGKYTLGHCTIRWAFMLAILSIGDALILSFLAFVLGYRQDKLLPDDYKADGNEEV
Protein: Kynurenine aminotransferase 1 (SRF6-like) (Surfeit 6) (Surfeit locus protein 6 isoform X1) (Q6DRK9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- EBNA1-binding protein 2.
- Ribosome production factor 1
- Nucleolar GTP-binding protein 1
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- Protein MAK16 homolog
- Ribosomal RNA-processing 1.
- RRP15-like protein
- Ribosome biogenesis protein BRX1 homolog
- Ribosomal L1 domain-containing protein 1
- Peter pan homolog.
Sequence:
MASLAAKYDYLEKLTRKVCVSHKQEPKKRAYVPFRGGGNDANEAAPSKKKKKNKQKQVKGDNANANKNKPVPKGTPATTPPAQRKTVQNGTSVTQNKPGGAASKDFNAVDILRQRLHQKIEESRGQGTPKDPSSDEVKMKREKRKQERERRKRKRKEFRLKKLADAAGLQPVDVKEIKTEPEEDSTATSSVPAKKEQSFIVFNKMEVGEDYVDKGTKMMEKKKRKVKGTLTPLTGKNYKQLLTRIEARKAHLEQLREKDEGKAKKEEEKMKWTNVLYKAEGMKIKDNEKLLHASLKKKEKMKAQRKKKWAMRSEQVVEKMQKRQDKRKRNIKRRADAKIEKRKQKARKKGRVLPGDVKKAGL
Protein: Beta-glucuronidase (GUS) (EC 3.2.1.31) (Beta-D-glucuronoside glucuronosohydrolase) (EcGUS) (UID) (P05804)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Glucuronide carrier protein homolog
- Uronate isomerase
- HTH-type transcriptional regulator UidR
- Membrane-associated protein UidC
- Aminodeoxychorismate synthase component 1
- Putative beta-xylosidase
- Tryptophan synthase alpha chain
- Tryptophan synthase beta chain
- Sodium/proline symporter
- Isocitrate dehydrogenase
Sequence:
MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ
Protein: Probable transcriptional regulator (Q9HXN8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable N-acetylglucosamine-6-phosphate deacetylase
- Probable aminotransferase
- phosphoenolpyruvate--protein phosphotransferase
- N-Acetyl-D-Glucosamine phosphotransferase system transporter
- Probable glycosyl hydrolase
Sequence:
MKTAHDLLLALRPDEAQPTPLYLQLARNLESAIHAGQWKAEEALPSERNLSETLNISRVTARKALEVLFEQGLIRRNQGSGTFITPRLEQPLSRLSSFSEMLRLKGFTPGSTWLERGIALPTHDELIRLGLSPTEKVTRMKRLRKADGTVMAIENSTLPARLLPDPTAVGDSLYEYLDGIGRPVVRALQHVRAINSSASDAALVGIAPGTAMLLMTRIGYLEDNTPIELTDTYCRNDYYDFVAELRR
Protein: ATP synthase F(0) complex subunit f, mitochondrial (ATP synthase membrane subunit f) (P56134)
Organism: Homo sapiens (Human)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Subcellular location: Mitochondrion. Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- ATP synthase F
- ATP synthase peripheral stalk subunit d, mitochondrial
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit F6, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit b, mitochondrial
Sequence:
MASVGECPAPVPVKDKKLLEVKLGELPSWILMRDFSPSGIFGAFQRGYYRYYNKYINVKKGSISGITMVLACYVLFSYSFSYKHLKHERLRKYH
Protein: Probable low-specificity L-threonine aldolase (EC 4.1.2.48) (O13940)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Putative glycine dehydrogenase
- Serine hydroxymethyltransferase, mitochondrial
- Threonine dehydratase, mitochondrial
- Threonine synthase
- Probable serine hydroxymethyltransferase, cytosolic
- L-pipecolate oxidase
- D-amino-acid oxidase
- 5-aminolevulinate synthase, mitochondrial
- NADP-dependent 3-hydroxy acid dehydrogenase
- Putative glycine cleavage system H protein, mitochondrial
Sequence:
MSGSVTSTTTETRLCPSNQGSAKKYRPWNDFRSDTLTVPTDEMRRIMYEASDGDCVYEEDEDTRKLEVYVAKLTGKEAALFVTSGTQGNQLCIRSHLHQPPHSIICDDRAHIYNWEAGAIGLFTQAIVRPISPKNNVYITAEEIENKLILGNDIHFSPTGLICLENTIKGAVVPLDEVARISGLAKAHKIPLHCDGARLWDAAVASNVSIKEYCSYFDSVSLCLSKGLAAPVGSIIVGPRDFIAKAKWFRKAYGGGLRQSGMLAAAGLYSIQHNFPLLKQVHKYAIEVAEYAESLGIELEVPTQSNMVTLANINVAILCDEAKKSGIILMGPRIVFHIQITPDAVEILKNVLRRTVERQAVETHIVAKPGEFCVGY
Protein: Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) (O60930)
Organism: Homo sapiens (Human)
Function: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Ribonuclease H2 subunit A
- Single-stranded DNA-binding protein, mitochondrial
- Thymidylate synthase
- Twinkle mtDNA helicase
- NAD-capped RNA hydrolase NUDT12
- NAD kinase
- Glyceraldehyde-3-phosphate dehydrogenase
- NAD
- Probable helicase senataxin
- Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
Sequence:
MSWLLFLAHRVALAALPCRRGSRGFGMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRKSASPEVSEGHENQHGQESEAKASKRLREPLDGDGHESAEPYAKHMKPSVEPAPPVSRDTFSYMGDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLPGRQTNQRAEIHAACKAIEQAKTQNINKLVLYTDSMFTINGITNWVQGWKKNGWKTSAGKEVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSED
Protein: Neurotactin (P23654)
Organism: Drosophila melanogaster (Fruit fly)
Function: May mediate or modulate cell adhesion between embryonic cells during development.
Subcellular location: Membrane {ECO:0000269|PubMed:2100266, ECO:0000269|PubMed:2120047}; Single-pass type II membrane protein {ECO:0000269|PubMed:2100266, ECO:0000269|PubMed:2120047}. Note=Expressed in membranes during embryogenesis.
Interaction partners:
- Protein amalgam
- Neuroglian
Sequence:
MGELEEKETPPTETTAAQQEALEEPKETDKMLDKKEDAKEKTPSPQTSKPASPNAGKKSSPVAEKKIDDAELAKSKSGNGEEIIDIPAENGTKPDSADDKKISKEEREVKPKKIPIGGLKLPGFFMKNKPKADGDGAEGELLEKEKEEDKDKEANGDAATGSGKDEQKSRPGLGERLRSFFARKPSAEKEKKQLVNGDADAKSEATAEATPAEDASDAPPKRGLLNAIKLPIANMIPKKKSNDDVELGLGKAGLASMETLDDSLKDQDTVDRAPVKTNGTEELKGELKDEKLAAEEKLAAEEEEQNRPVSLLTRLRGYKCSVDDALIVFGILLFVLLLGVIGYVLTHETLTSPPLREGRYIMAVTGCGPVEGVKEDGAFAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQRLGNGTTVGDEDCLYLDVVTPHVRYNNPLPVVVLIGAESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGSAILPGKPLSESGKQNEQLMATLECADIQCLREASSERLWAATPDTWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGATAHEAHTEKLRELHANWTREEVRAYLENSQIGALGLTDEVIEKYNASSYASLVSIISDIRSVCPLLTNARQQPSVPFYVVTQGEGPDQLATVDADVQAILGRYEPHTVEQRRFVSAMQQLFYYYVSHGTVQSFVQNRRVINVGQDAQPEEDYLPCNYWISKDIVPRYARVD
Protein: Inner kinetochore subunit AME1 (Associated with microtubules and essential protein 1) (CENP-U homolog) (Constitutive centromere-associated network protein AME1) (P38313)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore COMA complex, which connects centromere-associated proteins and the outer kinetochore. COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:29046335}.
Interaction partners:
- Inner kinetochore subunit MCM21
- Inner kinetochore subunit OKP1
- Inner kinetochore subunit CHL4
- Inner kinetochore subunit CTF19
- Inner kinetochore subunit NKP2
- Inner kinetochore subunit NKP1
- Inner kinetochore subunit IML3
- Inner kinetochore subunit MCM22
- Histone H3-like centromeric protein CSE4
- Inner kinetochore subunit MCM16
Sequence:
MDRDTKLAFRLRGSHSRRTDDIDDDVIVFKTPNAVYREENSPIQSPVQPILSSPKLANSFEFPITTNNVNAQDRHEHGYQPLDAEDYPMIDSENKSLISESPQNVRNDEDLTTRYNFDDIPIRQLSSSITSVTTIDVLSSLFINLFENDLIPQALKDFNKSDDDQFRKLLYKLDLRLFQTISDQMTRDLKDILDINVSNNELCYQLKQVLARKEDLNQQIISVRNEIQELKAGKDWHDLQNEQAKLNDKVKLNKRLNDLTSTLLGKYEGDRKIMSQDSEDDSIRDDSNILDIAHFVDLMDPYNGLLKKINKINENLSNELQPSL
Protein: Ferruginol synthase (EC 1.14.14.175) (11-oxomiltiradiene synthase) (EC 1.14.14.-) (Cytochrome P450 76AH24) (SpCYP76AH24) (Ferruginol monooxygenase) (11-hydroxyferruginol synthase) (EC 1.14.14.60) (A0A0S1TP26)
Organism: Salvia pomifera (Apple sage)
Function: Monooxygenase involved in the biosynthesis of labdane-related diterpenes natural products. Catalyzes the oxidation of abietatriene to produce ferruginol. Ferruginol is an intermediate in the biosynthesis of carnosate, a potent antioxidant. May also convert miltiradiene into 11-oxomiltiradiene.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLQLGSQPHETFAKLSKKYGPLMSIHLGSLYTVIVSSPEMAKEIMHKYGQVFSGRTIAQAVHACDHDKISMGFLPVGAEWRDMRKICKEQMFSHQSMEDSQNLRKQKLQQLLDYTQKCSEEGRGIDIREAAFITTLNLMSATLFSMQATEFDSKVTMEFKEIIEGVASIVGVPNFADYFPILRPFDPQGVKRRADVYFGRLLGLIEGYLNERIEFRKANPNAPKKDDFLETLVDALDAKDYKLKTEHLTHLMLDLFVGGSETSTTEIEWIMWELVASPEKMAKVKAELKSVMGGEKVVDESMMPRLPYLQAVVKESMRLHPPGPLLLPRKAESDQVVNGYLIPKGTQVLINAWAMGRDSSLWKNPDSFEPERFLDQKIDFKGTDYELIPFGSGRRVCPGMPLANRILHTVTATLVHNFDWKLERPEANDAHKGVLFGFAVRRAVPLKIVPIKA
Protein: DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) (O74833)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in ds DNA break repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:24847916}.
Interaction partners:
- ATP-dependent DNA helicase II subunit 1
- ATP-dependent DNA helicase II subunit 2
- DNA repair and recombination protein rad22
- Non-homologous end-joining factor xrc4
- Exodeoxyribonuclease 1
- Double-strand break repair protein rad32
- DNA repair protein rhp51
- Xrcc4-like factor 1
- Probable tyrosyl-DNA phosphodiesterase
- DNA replication ATP-dependent helicase/nuclease dna2
Sequence:
MDEAKETVFTKPQNHSSTLEFYDFVTTLLEPLSRIGKTRKSKTSNLDPYELKRKILLDYFNKWRQHVGPDLYPLLRLMLPDLDRERGSYGFKEFGLGKLFIRAMHLSPTSEDAKSLKNWRGSESKHTGDFSTMLQDILQRRAYRTFPGAFTVGDVNALLDQLADASSEDTRVNILEQFYRSLSPLELRWLIPILLKVRKYGTSEKFILSVFHPDAARLYRLCSSLKRICWELYDPSRSLDETETDVEVFSCFQPQLANFKKKDLHQTLEAMGNKPFWIEEKLDGERIQLHMSSGKFQFYSRNARSYTYAYGSSYFDEQSRLTQYIIGAFDKRISQIILDGEMVTWDPVLETVIPYGSLRSIFEDSSSHSSYSPYYVVFDILYLNGKSLVKYSLESRRRILEKVIVRESHRMSILPYKVGSTIEDIEAELRNVIQEGSEGLVIKKPSGSYHLGERMDDWIKVKPYYLQGFGEDLDCLILGGYFGRGKQSGKINSFLCGLRMDYTPKDHSEKFQSFVRVGGGFTYFDRDIIRKETEGKWLPWSSDALEYMELAGTKQDFEKPDMWIHPKDSLVLQIKAAEVVVSNRFKTNYTLRFPRLEKVRLDRSWKDALTINEFFTLKNAVEKQDNVSFHVNKKRKVSQKREKQKKFLYDEPTFKKEASPHSDVLKNLHFVVLPPTELHETKAGLQQIIIENGGLIHQGVGNFGKERLFLVADRVSTRVSIERSKNMCTIIRSQWVMDSVNNQRLMPQWSYLLFSKDEKYSWKTALESLSAKSLSNLLVELKQLDLSKEYSKISDDTSILNLTISKEEASFVGAFPFLKFTVFLDLKGIENSELYDVRMGQYRLTKCILLWNGATIEKDISSKKLTHVVMFVEDSTRLEQLTKACELYQIEPKFVNFEWVVNEWKKASTNILG
Protein: Heme-based aerotactic transducer HemAT (Q9HPR6)
Organism: Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Function: Heme-containing signal transducer responsible for aerotaxis, the migratory response toward or away from oxygen.
Interaction partners:
- Chemotaxis protein
- Protein-glutamate methylesterase/protein-glutamine glutaminase
- Chemotaxis protein CheA
- Chemotaxis protein
- Dipeptide ABC transporter ATP-binding
Sequence:
MSNDNDTLVTADVRNGIDGHALADRIGLDEAEIAWRLSFTGIDDDTMAALAAEQPLFEATADALVTDFYDHLESYERTQDLFANSTKTVEQLKETQAEYLLGLGRGEYDTEYAAQRARIGKIHDVLGLGPDVYLGAYTRYYTGLLDALADDVVADRGEEAAAAVDELVARFLPMLKLLTFDQQIAMDTYIDSYAQRLHDEIDSRQELANAVASDVEAPLSSLEATSQDVAERTDTMRAATDDQVDRMADVSREISSVSASVEEVASTADDVRRTSEDAEALAQQGEAAADDALATMTDIDEATDGVTAGVEQLRERAADVESVTGVIDDIAEQTNMLALNASIEAARAGEAGEGFAVVADEVKALAEESREQSTRVEELVEQMQAETEETVDQLDEVNQRIGEGVERVEEAMETLQEITDAVEDAASGMQEVSTATDEQAVSTEEVAEMVDDVDDRAGEIAAALDDIADATDQQVRTVEEVRETVGKLS
Protein: Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein) (P60880)
Organism: Homo sapiens (Human)
Function: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P60879}. Cell membrane {ECO:0000250|UniProtKB:P60881}; Lipid-anchor {ECO:0000250|UniProtKB:P60879}. Synapse, synaptosome {ECO:0000250|UniProtKB:P60879}. Photoreceptor inner segment {ECO:0000250|UniProtKB:P60879}. Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity). Colocalizes with PLCL1 at the cell membrane (By similarity). {ECO:0000250|UniProtKB:P60879, ECO:0000250|UniProtKB:P60881}.
Interaction partners:
- Syntaxin-1A
- Syntaxin-binding protein 1
- Synaptotagmin-1
- Complexin-1
- Vesicle-associated membrane protein 3
- Vesicle-associated membrane protein 2
- Syntaxin-4
- Syntaxin-binding protein 5
- Vesicle-associated membrane protein 7
- Syntaxin-1B
Sequence:
MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG
Protein: C2H2 finger domain protein, putative (Q4WCW8)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDVASLISPSESDTVPTFRSRSIQNSSASHYKRLSEQSTGSYFSAVPTHTTSYSRTPQPPLSPPAEDQSKCSLPSISILLENADGAAAHAAKRQRNSLSTHRDSDPRPPYDSITPHAMPPTPPLRPGSGFHSNGHSPSTSSVSAASSSALMKNTESYPQAPIGLPSPTDRSSISSQGSVQHAASAPYASPAPSVSSFSSPIEPSTPSTAAYYQRNPAPNTFQNPSPFPQTSTASLPSPGHQQMISPVTPAWQHHHYFPPSSSTSYQQNHDRYICRTCHKAFSRPSSLRIHSHSHTGEKPFRCTHAGCGKAFSVRSNMKRHERGCHTGRPVATAMVQ