wanglab/gogpt-training-data huggingface dataset:
Protein: Syntaxin-1A (Neuron-specific antigen HPC-1) (Synaptotagmin-associated 35 kDa protein) (P35A) (P32851)
Organism: Rattus norvegicus (Rat)
Function: Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm (By similarity). Also plays an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1) (By similarity).
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:O35526}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:O35526}. Cell membrane {ECO:0000269|PubMed:17301173, ECO:0000269|PubMed:18167541, ECO:0000269|PubMed:20484665, ECO:0000269|PubMed:22411134, ECO:0000269|PubMed:23341457}. Synapse, synaptosome {ECO:0000250|UniProtKB:O35526}. Note=Colocalizes with KCNB1 at the cell membrane (PubMed:17301173). Colocalizes with PLCL1 at the cell membrane (PubMed:22673903). {ECO:0000269|PubMed:17301173}.
Interaction partners:
- Multifunctional fusion protein
- Syntaxin-binding protein 1
- Vesicle-associated membrane protein 2
- Alpha-soluble NSF attachment protein
- Vesicle-associated membrane protein 1
- Complexin-1
- Synaptosomal-associated protein 23
- Vesicle-associated membrane protein 3
- Vesicle-associated membrane protein 8
- Vesicle-associated membrane protein 4
Sequence:
MKDRTQELRTAKDSDDDDDVTVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIIIASTIGGIFG
Protein: Galectin (Q95ZI4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MAEPKSFNIPYRSKLTERIEPGQTLIIRGKTIDESKRFNINLHKDSPDFSGNDVPLHLSIRFDEGKIVYNAYTKGTWGKEERAKNPIKKGDDFDIRIRAHDSKFQVSINHKEVKNFEHRIPLNSVSHLSIDGDVVLNHVQWGGKYYPVPYESGIAADGLVPGKTLVVYGTPEKKAKKFNINLLKKNGDIALHFNPRFDEKSVVRNSLVNGEWGNEEREGKNPFERLTAFDLEIRNEEFAFQIFVNGERFASYAHRVDPHDIAGLQIQGDIELTGIQVVNNQPAQE
Protein: Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A) (P17081)
Organism: Homo sapiens (Human)
Function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15546864}. Cell membrane {ECO:0000269|PubMed:15546864}; Lipid-anchor {ECO:0000269|PubMed:15546864}.
Interaction partners:
- Exocyst complex component 7
- Golgi-associated PDZ and coiled-coil motif-containing protein
- Rap guanine nucleotide exchange factor 1
- Cdc42 effector protein 3
- Adapter molecule crk
- Cdc42 effector protein 4
- Cdc42-interacting protein 4
- Cdc42 effector protein 2
- Exocyst complex component 4
- Exocyst complex component 3
Sequence:
MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
Protein: Shaggy-related protein kinase gamma (EC 2.7.11.1) (ASK-gamma) (Shaggy-related protein kinase 12) (AtSK12) (P43289)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May mediate extracellular signals to regulate transcription in differentiating cells. Probably involved first at the cortical polarity site, to restrict MAPK signaling and promote asymmetric cell division (ACD), and second in the nucleus of stomatal lineage ground cells (SLGCs) or meristemoids, to limit cell division and to promote differentiation into pavement or stomatal guard cells, respectively. Phosphorylate YDA and SPCH in vitro.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:30429609}. Cytoplasm, cell cortex {ECO:0000269|PubMed:30429609}. Note=Localized throughout the plasma membrane in asymmetric cell division (ACD) precursors (PubMed:30429609). Accumulates transiently in a polarized pattern at the plasma membrane immediately before ACD, relocalizing to well-defined foci, in a POLAR-dependent and in the presence of BASL (PubMed:30429609). {ECO:0000269|PubMed:30429609}.
Interaction partners:
- AT-rich interactive domain-containing protein 3
- Extensin-like protein
- Transcription factor LRL2
- Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein
- Probable nucleolar protein 5-2
- Proline-rich extensin-like family protein
- Small ribosomal subunit protein uS10m
- Neutral ceramidase 3
- Extensin-like protein
- Neutral ceramidase 2
Sequence:
MASVGIEPSAAVRESTGNVTDADRLPEEMKDMKIQDDKEMEATIVNGNVTETGHIIVTTIGGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELRDPNARLPNGRFLPPLFNFKPHELKGVPVEMVAKLVPEHARKQCPWLSL
Protein: C1q-related factor (C1q and tumor necrosis factor-related protein 14) (C1q/TNF-related protein 14) (CTRP14) (Complement component 1 Q subcomponent-like 1) (O88992)
Organism: Mus musculus (Mouse)
Function: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.
Subcellular location: Secreted.
Interaction partners:
- Adhesion G protein-coupled receptor B3
Sequence:
MLLVLVVLIPVLVSSGGPDGHYEMLGTCRMVCDPYPARGPGAGARSDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDRGPPGPVGPPGEKGEPGKPGPPGLPGSGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD
Protein: Mitochondrial fission 1 protein A (FIS1 homolog A) (AtFIS1a) (Protein BIGYIN 1) (Q9M1J1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the peroxisomal and mitochondrial division machineries. Plays a role in promoting the fission of mitochondria and peroxisomes.
Subcellular location: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Dynamin-related protein 3A
- Dynamin-related protein 3B
- Peroxisomal membrane protein 11C
- Dynamin-like protein ARC5
- Peroxisomal membrane protein 11E
- Peroxisomal membrane protein 11B
- Peroxisomal membrane protein 11D
- Dynamin
- Peroxisome biogenesis protein 12
- Peroxisomal and mitochondrial division factor 1
Sequence:
MDAKIGQFFDSVGTFFSGSDKIPWCDGDVIAGCEREVREATDSGTEDLKKECLMRLSWALVHSRQTEDVQRGIAMLEASLESSAPPLEDREKLYLLAVGYYRSGNYSRSRQLVDRCIEMQADWRQALVLKKTIEDKITKDGVIGIGITATAFGAVGLIAGGIVAAMSRKK
Protein: Caspase 9 (Q90WU0)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
WAAGRGRGSRSYRPGDRALCPLSSMTGPEHRHPKEQARQLVIDLETRGKQAFPIFLSILRDTGHGDLADMLDEGCGSPMSPPVDLRPVQLELPGDRRDKSVSTAERLSIPVQPESERFRMPPAPAQGSAVDKSRPTDWCTSCEQTPCGHCLIFNNVSFSRDSDLSTRAGSDIDCEKLEKRFRSLCFHVRTLRNLKAQEIDVELRKLARLDHSALDCCLVVILSHGCQTSHIQFPGGIYGTDGKIIPIERIVNYFNGSQCPSLRGKPKLFFIQACGGEQKDQGFEVDCESPQDETCRRSIESDAIPFQAPSGNEDEPDAVASLPTPGDILVSYSTFPGFVSWRDKVSGSWYVETLDSVLEHYARSEDLLTKLLRVSDIVSSKGRYKQIPGCFNFLRKKIFFLCK
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 (Q9BU61)
Organism: Homo sapiens (Human)
Function: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Subcellular location: Nucleus {ECO:0000250}. Mitochondrion inner membrane {ECO:0000269|PubMed:19463981}.
Interaction partners:
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Complex I assembly factor TIMMDC1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex assembly factor 4
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- Complex I intermediate-associated protein 30, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- Arginine-hydroxylase NDUFAF5, mitochondrial
Sequence:
MATALALRSLYRARPSLRCPPVELPWAPRRGHRLSPADDELYQRTRISLLQREAAQAMYIDSYNSRGFMINGNRVLGPCALLPHSVVQWNVGSHQDITEDSFSLFWLLEPRIEIVVVGTGDRTERLQSQVLQAMRQRGIAVEVQDTPNACATFNFLCHEGRVTGAALIPPPGGTSLTSLGQAAQ
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 (Q8RUX8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Complex I assembly factor TIMMDC1, mitochondrial
- Putative methyltransferase At1g22800, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 8-A
- NADH dehydrogenase 1 alpha subcomplex subunit 13-A
- NADH dehydrogenase 1 alpha subcomplex subunit 13-B
- NADH dehydrogenase 1 alpha subcomplex subunit 8-B
- NADH:ubiquinone oxidoreductase intermediate-associated protein 30
- Probable complex I intermediate-associated protein 30
- NADH dehydrogenase 1 beta subcomplex subunit 10-B
- NADH dehydrogenase 1 beta subcomplex subunit 10-A
Sequence:
MAMRLKSMATLPKLIQSMRKEVPKHSNPVLPSLRRAFSLYDQINLIDNVPEDQLRFQEFNDTSFTVNGVKYEGSLLCVGNLLMSWSPRKFSEITTDSLSIFQTVRPIPELLIVGCGRDIHPVTPEVRQFVKSLGMKLETVDSRNAASTYNILNEEGRVVAAALLPYGVTS
Protein: Trehalose 6-phosphate phosphatase (EC 3.1.3.12) (C9QPE7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Trehalase
- Trehalase
- BcDNA.GH08860
- Trehalose 6-phosphate phosphatase
- GEO08194p1
- Protein YIPF
- Glucose-6-phosphate isomerase
Sequence:
MKSIVFLLALLLNATRSYREIVKMPEKQVAPVISNLEDFANNLPGYLISESPVAVLLDYDGTLAPIADNPAKTKMPVELEAILHKIAKHPKVFLAVISGRGLKDVQKQVNIDGITYAGNHGLEIEYPDGSRHDYELPTEIQKNYTQMVRELKEKVEKNGAWVEDKKVSLTYHYRDTPAALKDQQKQLASEICTKFGFRANQAHEAIEAKPPVNWNKGEAAVYILKQKFGDNWSQKVSVVFAGDDTTDEDAMRVLRGLGRSFRISADAQIQTYADFRLPKQAVMTDLLKWIANVYVS
Protein: DNA polymerase (EC 2.7.7.7) (P03261)
Organism: Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
Function: Eukaryotic-type DNA polymerase involved in viral genomic replication. DNA synthesis is protein primed, and acts in a strand displacement replication. Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication. The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
Subcellular location: Host nucleus {ECO:0000255|HAMAP-Rule:MF_04055}.
Interaction partners:
Sequence:
MALVQAHRARRLHAEAPDSGDQPPRRRVRQQPPRAAPAPARARRRRAPAPSPGGSRAPPTSGGPPASPLLDASSKDTPAAHRPPRGTVVAPRGCGLLQVIDAATNQPLEIRYHLDLARALTRLCEVNLQELPPDLSPRELQTMDSSHLRDVVIKLRPPRADIWTLGSRGVVVRSTITPLEQPDGQGQAAEVEDHQPNPPGEGLKFPLCFLVRGRQVNLVQDVQPVHRCQYCARFYKSQHECSARRRDFYFHHINSHSSNWWREIQFFPIGSHPRTERLFVTYDVETYTWMGAFGKQLVPFMLVMKFGGDEPLVTAARDLAVDLGWDRWEQDPLTFYCITPEKMAIGRQFRTFRDHLQMLMARDLWSSFVASNPHLADWALSEHGLSSPEELTYEELKKLPSIKGTPRFLELYIVGHNINGFDEIVLAAQVINNRSEVPGPFRITRNFMPRAGKILFNDVTFALPNPRSKKRTDFLLWEQGGCDDTDFKYQYLKVMVRDTFALTHTSLRKAAQAYALPVEKGCCAYQAVNQFYMLGSYRSEADGFPIQEYWKDREEFVLNRELWKKKGQDKYDIIKETLDYCALDVQVTAELVNKLRDSYASFVRDAVGLTDASFNVFQRPTISSNSHAIFRQIVFRAEQPARSNLGPDLLAPSHELYDYVRASIRGGRCYPTYLGILREPLYVYDICGMYASALTHPMPWGPPLNPYERALAARAWQQALDLQGCKIDYFDARLLPGVFTVDADPPDETQLDPLPPFCSRKGGRLCWTNERLRGEVATSVDLVTLHNRGWRVHLVPDERTTVFPEWRCVAREYVQLNIAAKERADRDKNQTLRSIAKLLSNALYGSFATKLDNKKIVFSDQMDAATLKGITAGQVNIKSSSFLETDNLSAEVMPAFEREYSPQQLALADSDAEESEDERAPTPFYSPPSGTPGHVAYTYKPITFLDAEEGDMCLHTLERVDPLVDNDRYPSHLASFVLAWTRAFVSEWSEFLYEEDRGTPLEDRPLKSVYGDTDSLFVTERGHRLMETRGKKRIKKHGGNLVFDPERPELTWLVECETVCGACGADAYSPESVFLAPKLYALKSLHCPSCGASSKGKLRAKGHAAEGLDYDTMVKCYLADAQGEDRQRFSTSRTSLKRTLASAQPGAHPFTVTQTTLTRTLRPWKDMTLARLDEHRLLPYSESRPNPRNEEICWIEMP
Protein: Ionotropic GABA receptor subunit UNC-49Cshort (Neurotransmitter-gated ion-channel transmembrane domain-containing protein) (G5EDM9)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MCSDAYSTAEIEYKWCTSKEPNCSTAVKADANIELSSYKFTKICQKRTLASTSSGTYSRLRVSFIFDRDSGFYFLQIFFPASLVVVLSWISFWINRDSAPSRTLIGTMTVLTETHLMTGTNRRLPPVAYVKAVDVFLGFCYLLVILALIEYACVAYSKKKNEDRRRREKKTEHKPAPPTPDILHDVRLAECTCNAAPTSIIAVIKQSNRFCVSHSHIDIVSRAAFPLVFILFNTLFWLILLYKSKRLPYISEHEGDRCDAPDLH
Protein: PBX3 protein (Q96AL5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
EKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQSLVKDPKERGSKGSDIQPTSVVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN
Protein: CDKN1A interacting zinc finger protein 1 (A2AN61)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFNPQLQQQQQLQQQQQQLQQQLQQQQLQQQQQQILQLQQLLQQSPPQASLSIPVSRGLPQQSSPQQLLSLQGLHSTSLLNGPMLQRALLLQQLQGNLRAFNVTAPSLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGVPINPSQLNHSGRNTQKQARTPSSTTPNRKDSSSQTVPLEDREDPTEGSEEATELQMDTCEDQDSLVGPDSMLSEPQVPEPEPFETLEPPAKRCRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPEHLAPQQDQVEPQVPSQPPWQLQPRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATEPQLSSHAAEAGSDPDKALPEPVSAQSSEDRSREASAGGLDLGECEKRAGEMLGMWGAGSSLKVTILQSSNSRAFNTTPLTSGPRPGDSTSATPAIASTPSKQSLQFFCYICKASSSSQQEFQDHMSEAQHQQRLGEIQHSSQTCLLSLLPMPRDILEKEAEDPPPKRWCNTCQVYYVGDLIQHRRTQEHKVAKQSLRPFCTICNRYFKTPRKFVEHVKSQGHKDKAQELKTLEKETGSPDEDHFITVDAVGCFESGQEEDEDDDEEEEEEGEIEAEEEFCKQVKPRETSSEQGKGSETYNPNTAYGEDFLVPVMGYVCQICHKFYDSNSELRLSHCKSLAHFENLQKYKAKNPSPPPTRPVSRKCAINARNALTALFTSSHQPSPQDTVKMPSKVKPGSPGLPPPLRRSTRLKT
Protein: Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1) (O15269)
Organism: Homo sapiens (Human)
Function: Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. Required for adipocyte cell viability and metabolic homeostasis (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21618344}; Single-pass membrane protein {ECO:0000250|UniProtKB:O35704}.
Interaction partners:
- Serine palmitoyltransferase 2
- Serine palmitoyltransferase small subunit A
- ORM1-like protein 3
- Serine palmitoyltransferase small subunit B
- Serine palmitoyltransferase 3
- 3-ketodihydrosphingosine reductase
- ORM1-like protein 1
- ORM1-like protein 2
- Alpha-1-acid glycoprotein 1
- Palmitoyltransferase ZDHHC9
Sequence:
MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERSDLTVKEKEELIEEWQPEPLVPPVPKDHPALNYNIVSGPPSHKTVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLKVVGESLSPAFHLQLEESTGSREQDVRLLQEIVDQCMNRSIALTQARYLEKEEKCLPPPSIRVVVTVEQTEEELERAASTIKEVAQAVLL
Protein: Branched-chain amino acid ABC transporter, permease protein (Q5LV78)
Organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, periplasmic substrate-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
Sequence:
MGFYLAQLLTGLANASSLFLIASGLSIIFGVTRIVNFAHGSFYMLGAYLAYTLVTTLQGGIPGYWFSVLAAAVLVGGIGLVVELTILRRIYRAPELFQLVATFGVVLIVQDLTLAIWGAEDLLGPRAPGLDRAVRLMGEPIPEYDLALIAIGPAVLAAIWLVFHRTRWGVLVRAATQDREMVGALGVNQAWLFSAAFVLGSALAGLGGALQIPREAVSLQMDLSIIGEAFVVVVIGGMGSVTGAFVAAVLISVLNAFAILIFPQISIVLPFVVMAAVLIVRPYGLFGRPGSEHGGAEEPEQPLRLLDQRSTMVLLALVAMLAFSPAVVSDFTTILLVDVMVATLFAVSLHFMMGVGGMVSFGHAAYFGVGAYAAAMATKMLGWGMLPSMALGPVAAALAALFFGWFCVRLSGVYLAMLTMAAAQILWGVTFQWQDVTGGDDGILGVWPAAWAKSDQVYFYLALVLCLGGIWLLRRVAHSPFGYTLRGVRDSRIRAEAIGIDTRFHQWMGFTLAGTLAGLAGAVFVFSKGSVFPDALSIGHSIDGLIMVLLGGIHALAGPVYGAMAMVLIEDWVSRLDYWRFIFGGIILTVVLLAPDGIAGGVRRLIQLVRRDAA
Protein: Solute carrier family 12 member 3 (Q1LX46)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Sodium-dependent phosphate transporter 1-A
- Anion exchange protein.
- Cadherin 17, LI cadherin
- Transient receptor potential cation channel, subfamily M, member 7.
- Slow myosin heavy chain 1
- Chloride channel protein.
- WT1 transcription factor b.
- Metal transporter
- Sodium/hydrogen exchanger
- NPHS1 adhesion molecule, nephrin.
Sequence:
MNLQSARSPFSVSSLSNGDDRKFSLGGCSSYDTDSVASRSSGVFSGYDTLDAPPSYDFYTNTEVFGRAKKSRPSLFELHSNPQDDPSPPPLYEESSVDKQSPEDEDEPTEPPPEPARFGWAQGVMIRCMLNIWGVILYLRLPWITAQAGIGLTWIIILVSSSITGITGLSTSAIATNGKVKGGGTYFLISRSLGPELGGSIGLIFAFANAVAVAMHTVGFAETVQVLMQETEVSMVDKLNDIRIIGVITVTCLLAISMAGMEWESKAQVLFFFVIMISFASYIIGTIIPATPQKQARGFFSYRADIFATNFVPGWRGPEGSFFGMFSIFFPSATGILAGANISGDLKDPNVAIPRGTMLAIFWTTVSYLIISATIGSCVVRDASGDVNDTISSLTGECLGVGCNYGWNFTDCMTNNTCTYGLSNYYQSMSMVSAVAPLITAGIFGATLSSALACLVSAPKVFQCLCKDKLYPGIGFFGKGYGKNNEPLRSYLLAYIIAICFILIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPTFRFYSKWLSLLGAVVSVIIMFLLTWWAALIAIGIVIFLLGYVLYKKPEVNWGSSMQASSYNMALSQCVGLNQVEDHIKNYRPQCLVLSGPPCARPSLVDFIGAFTKNQSLMICANVLASGPSPGTADSMSSTHLKWLNNRKIKSFYHTVVADDLRTGVQMLLQSTGLGRMKPNVLVMGYKKNWRKVQPGIIENYVGILHDAFDLQYGVCVLRMKEGLDITRTIQAQVNLGFETSTEQGLDTNSTAPTSPTIEASLDPETLMALTQPSTLFQTRQGKKTIDVYWLSDDGGLTLLIPYLLTRKKRWGRCKVRVFVGGEAQQIEEQKKELKGLISRFRLGFKDIQVLPDINGAPQSEHIRKFEDFIAPYRVSSVQKDGQEADEATKEFSWMVSDEEMETFKAKSLRQIRLNEVIQDYSRDAALIVVTMPVGRRGSCPSPLYMAWLEIVSRDLRPPVLLVRGNQENVLTQYCQ
Protein: ToMV resistance protein Tm-2(2) (Disease resistance protein Tm-2(2)) (ToMV resistance protein Tm-2a) (Q71BG9)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Inhibitor of viral mouvements which confers resistance to some tobamoviruses including tomato mosaic virus (ToMV) (e.g. strains L, B7 and ToMV1-2) and tobacco mosaic virus (TMV), but not to resistance-breaking isolates (e.g. LIIA and ToMV2(2)) ToMV and tomato brown rugose fruit virus (ToBRFV). Elicits a hypersensitive reaction in response to avirulent (Avr) movement proteins from resistance inducing tobamoviruses (e.g. ToMV and TMV) strains, thus leading to programmed cell death; this local extreme resistance requires rbcS.
Subcellular location: Cell membrane {ECO:0000269|PubMed:28258211}; Peripheral membrane protein {ECO:0000269|PubMed:28258211}; Cytoplasmic side {ECO:0000305|PubMed:28258211}.
Interaction partners:
- ToMV resistance protein Tm-1
- ToMV susceptible protein tm-1
- Verticillium wilt disease resistance protein
- RNA helicase
Sequence:
MAEILLTSVINKSVEIAGNLLIQEGKRLYWLKEDIDWLQREMRHIRSYVDNAKAKEAGGDSRVKNLLKDIQELAGDVEDLLDDFLPKIQQSNKFNYCLKRSSFADEFAMEIEKIKRRVVDIDRIRKTYNIIDTDNNNDDCVLLDRRRLFLHADETEIIGLDDDFNMLQAKLLNQDLHYGVVSIVGMPGLGKTTLAKKLYRLIRDQFECSGLVYVSQQPRASEILLDIAKQIGLTEQKMKENLEDNLRSLLKIKRYVILLDDIWDVEIWDDLKLVLPECDSKVGSRMIITSRNSNVGRYIGGESSLHALQPLESEKSFELFTKKIFNFDDNNSWANASPDLVNIGRNIVGRCGGIPLAIVVTAGMLRARERTEHAWNRVLESMGHKVQDGCAKVLALSYNDLPIASRPCFLYFGLYPEDHEIRAFDLINMWIAEKFIVVNSGNRREAEDLAEDVLNDLVSRNLIQLAKRTYNGRISSCRIHDLLHSLCVDLAKESNFFHTAHDAFGDPGNVARLRRITFYSDNVMIEFFRSNPKLEKLRVLFCFAKDPSIFSHMAYFDFKLLHTLVVVMSQSFQAYVTIPSKFGNMTCLRYLRLEGNICGKLPNSIVKLTRLETIDIDRRSLIQPPSGVWESKHLRHLCYRDYGQACNSCFSISSFYPNIYSLHPNNLQTLMWIPDKFFEPRLLHRLINLRKLGILGVSNSTVKMLSIFSPVLKALEVLKLSFSSDPSEQIKLSSYPHIAKLHLNVNRTMALNSQSFPPNLIKLTLAYFSVDRYILAVLKTFPKLRKLKMFICKYNEEKMDLSGEANGYSFPQLEVLHIHSPNGLSEVTCTDDVSMPKLKKLLLTGFHCRISLSERLKKLSK
Protein: T. brucei spp.-specific protein (Q386W5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGSECSRHSNQTELRDERFCSKRRQVLDATLAQAPRPPSFVNLSNDYRCCCGAVGPGGLRFAEPPNRGSTTGPPRDHRPGITGNRRSERPGNLGQVSSLYPAVEPHRGLPSRDQPKSTLFPQSCPKASTSKVNTHVRARSEPHTRGGRRAGSKISVANASGSRSKRSKLTSYVDDNENVQGVHEFRKKLIFLSLEEEKERLQISNERLTGFCNMEDIFVRSMKGTPHCSAELKLFSLQGRRREFIREQEHNEWRQLLFSVNQTLLNSSLDGKAKGFAYSHLDENSLYWPSPTSERGCIRRPFTAAELNQLARSNSETDFYVSSDGLKKPTSHATKMCALCEVALKNVLSEDIIDIDRINRKIARQIYLLNEISSYCSPTDSGSSACSKERVAGMCPLTTNDNLQSVACRPLRLPPRASTTTCTSYPVGHSCCGSVSSTSKGLPDYLRKECNFATRKRLVSLLQE
Protein: Actin-1 (EC 3.6.4.-) (P0DM41)
Organism: Caenorhabditis elegans
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Actin-related protein 2
- Actin-related protein 3
- Actin-2
- Actin-related protein 2/3 complex subunit
- Actin-depolymerizing factor 2, isoform c
- Probable actin-related protein 2/3 complex subunit 4
- Probable actin-related protein 2/3 complex subunit 3
- Probable actin-related protein 2/3 complex subunit 2
- Tropomyosin isoforms a/b/d/f
- Actin-related protein 2/3 complex subunit 5
Sequence:
MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGVVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITVGNERFRCPEAMFQPSFLGMESAGIHETSYNSIMKCDIDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
Protein: UTP4 small subunit processome component (I3L4T9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASVDLSYCSFLHLLLLCSPILACPPLNGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVF
Protein: Annexin D4 (AnnAt4) (Q9ZVJ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in osmotic stress and abscisic acid signaling in a calcium-dependent manner.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase
Sequence:
MALPLELESLTEAISAGMGMGVDENALISTLGKSQKEHRKLFRKASKSFFVEDEERAFEKCHDHFVRHLKLEFSRFNTAVVMWAMHPWERDARLVKKALKKGEEAYNLIVEVSCTRSAEDLLGARKAYHSLFDQSMEEDIASHVHGPQRKLLVGLVSAYRYEGNKVKDDSAKSDAKILAEAVASSGEEAVEKDEVVRILTTRSKLHLQHLYKHFNEIKGSDLLGGVSKSSLLNEALICLLKPALYFSKILDASLNKDADKTTKKWLTRVFVTRADHSDEMNEIKEEYNNLYGETLAQRIQEKIKGNYRDFLLTLLSKSD