wanglab/gogpt-training-data huggingface dataset:
Protein: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (Brefeldin A-inhibited guanine nucleotide-exchange protein 2) (E7FCG1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi apparatus, trans-Golgi network {ECO:0000256|ARBA:ARBA00004601}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Dachsous cadherin-related 1b.
- Integrator complex subunit 8
- ADP-ribosylation factor-like protein 1
- FAT atypical cadherin 4.
- NEDD4-like E3 ubiquitin protein ligase.
- SEC63 homolog, protein translocation regulator.
Sequence:
MKEQEALATHRRHTQTESLSTKSMFLSRALEKILADKEVKRSQHNQLRKACQVALDEIKHELEKQKDGTVVPPRANYIEADKYVLPFELACQSKSPRIVSTSLDCLQKLIAYGHITGNAPDSAAPGKRLIDRLVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTILLTVRTCYNIYLASRNLINQTTAKATLTQMLNVIFTRMENQAALEAQEAEKERQRLQLRNPSPVSSNPSPVNQNPSQTPGRGSGSPWMGRACSEQNGSPCLSPPGVPSTPSTPQDSSSINSRPEEEFATDKQSTKDITHPDEELQESDQTTVDPSVTGGVEGEETHPQSETEAGSEVLEETEPDSGLGDSSVEGGLDQHSDSETRMPPPVVRVDTQQMNGMVDDRGSESSTDMLDAESIHGSQTAARFSHILQKDAFLVFRSLCKLSMKPLADGPPDPKSHELRSKVVSLQLLLSVLQGAGPVFRTHEMFVNAIKQYLCVALSKNGVSSVPEVFELSLAIFLTLLSHFKVHLKMQIEVFFREIFLTILETSSSSFEHKWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGQELGMTPLQELSLRKKGLECLVSILKCMVEWSRDMYVNPNLQANLGQERPAEGDSADVKLSEHLSSRRDSVSSLDSTVSSGVQQSQPDHPEQYEVIKQQKEIIEHGIELFNKKPKRGLQYLQEQGMLGTSPEDIAQFLQQEERLDTTQVGEFLGENVKFNKEVMYCYVDRLDFCGKDFVSALRAFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYDEIAGKKIAMKESKEYSITPKSSKQNVANEKQRRLLYNMEMEQMAKTAKALMEAVSHAQAPFFSATHLEHVRPMFKLAWTPLLAAFSVGLQDCDDQDVASLCLEGIRCAIRIACIFNMQLERDAYIQALARFTLLTASSSITEMKQKNIDTIKTLIMVAHTDGNYLGNSWHEILRCISQLELAQLIGTGVKMRISGVVRDQGGGIKGFPSGGEEFMPLGLGTLVGGPDKRQMAHIQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASAHQPRMFSLQKIVEISYYNMNRIRLQWSRIWQVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIVKKNRSPTIRDMVIRCVAQMVNSQAANIRSGWKNIFSVFHQAASDHDENIVDLAFQTTGHIVMNTFQQHFAAAIDSFQDAVKCLSEFVCNAAFPDTSMEAIRLIRHCAKYVSERPQALREYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWHDLFRIIFRIFDNMKLPEQQTEKTEWMTTTCNHALYAICDVFTQFYEPLSEVLLADIFAQLQWCVKQDNEQLARSGTNCLENLVILNGEKFSPEVWDVTCSCMLDIFQTTSPHALLTWRPAGQEEEVGEGKHMDVEVDSQSQSSFERTLSERGHSQMSTASDETWKGKSHTRVSDHRLFAGLLIKCVVQLELIQTIDNIVFYPATSKREDAENMAAAQRDALEQAEEGEAEVDQGMYRHLSSQHLFKLLDCLLESHRFAKDFNSNNEQRTALWRAGFKGKSKPNLLKQETSSLACSLRILFRMYSDTQLRDSWPDIQTRLLHVCSEALAYFISLTSESHREAWTSLLLLLLTRTLRLPDDKFKPHASCYYHHLCEMMQFDLIPELRAVLRRFFLRIGSVFHIAAPELGQAQPSSSSSSS
Protein: Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2) (Vesicle transport-related protein Ra410) (Q62991)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9195952}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:9195952}; Peripheral membrane protein {ECO:0000269|PubMed:9195952}. Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:9195952}; Peripheral membrane protein {ECO:0000269|PubMed:9195952}.
Interaction partners:
- BET1 homolog
- Golgi SNAP receptor complex member 2
- Syntaxin-5
- Golgi SNAP receptor complex member 1
- Synaptobrevin homolog YKT6
- Vesicle-trafficking protein SEC22b
- General vesicular transport factor p115
- Vesicle-trafficking protein SEC22a
- Vesicle-fusing ATPase
- Alpha-soluble NSF attachment protein
Sequence:
MVGSKMAASIRERQTVALKRMLNFNVPHVKNSPGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIRDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAANAVTQVAKVFDQYLNFITLEEDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDPLGTGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPTGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAPSEVDLEQYKKALTDAGCNLSPLQYIKQWKAFAKMASTPASYGNTTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRSNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKGKQGKHILYGCSEIFNATQFIKQLSQLGQK
Protein: Rothein 2.1 (P86509)
Organism: Litoria rothii (Roth's tree frog) (Hyla rothii)
Function: Lacks antimicrobial activity. Does not inhibit the formation of NO by neuronal nitric oxide.
Subcellular location: Secreted {ECO:0000269|PubMed:16124032}.
Interaction partners:
Sequence:
AGGLDDLLEPVLNSADNLVHGL
Protein: Flippase kinase 1 (EC 2.7.11.1) (P53739)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Flippase activator that phosphorylates DNF1 and DNF2 and which is involved in the generation of phospholipid asymmetry in membranes by the inward translocation of phospholipids and in the retrieval pathway from early endosomes to the trans-Golgi network (TGN). Phosphorylates also the N-terminal half of YPK1. Involved in pheromone-response.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Cell membrane {ECO:0000269|PubMed:14562095}; Peripheral membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Phospholipid-transporting ATPase DNF1
- Phospholipid-transporting ATPase DNF2
- Probable phospholipid-transporting ATPase DNF3
- Serine/threonine-protein kinase YPK1
- Protein ORM1
- Phospholipid-transporting ATPase accessory subunit LEM3
- Phospholipid-transporting ATPase NEO1
- Protein ORM2
Sequence:
MAGHHHEHEQERDHEQEHEHDSLQRPTTGSERTRSISFSKLLTRSWKRNASSSNNMSVSSVNLYSDPENSRESDHNNSGSEGQSSRFSKLKSMFQSGNSSKNASAHNSSQSSLEGDSASSSSKLRYVKPMTSVANASPASPPLSPTIPETDVLQTPKMVHIDQHEHEREHSNCGSPIMLSSSSFSPTVARTGTGRRRSPSTPIMPSQNSNNSSSTSAIRPNNYRHHSGSQGFSSNNPFRERAGTVRSSNPYFAYQGLPTHAMSSHDLDEGFQPYANGSGIHFLSTPTSKTNSLTNTKNLSNLSLNEIKENEEVQEFNNEDFFFHDIPKDLSLKDTLNGSPSRGSSKSPTITQTFPSIIVGFDNEYEEDNNNDKHDEKEEQQTTTDNKTRNLSPTKQNGKATHPRIKIPLRRAASEPNGLQLASATSPTSSSARKTSGSSNINDKIPGQSVPPPNSFFPQEPSPKISDFPEPRRSRRLRTKSFSNKFQDIMVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQEPPLIPVLSEDGYDFAKLSSNKKRQTSQDSHKHLDEQEKNMFEERVEYDDEVSEDDPFHDFNSMSLMEQDNNSMIYGNTNSYGKIAYTPNSNRSRSNSHRTFFKR
Protein: Cell pattern formation-associated protein stuA (Stunted protein A) (P36011)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Transcription factor that regulates asexual reproduction. Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes. Required from the very earliest events of asexual reproduction until completion of conidiophore development, but is not specifically required for differentiation of conidia. Represses transcription of the abaA developmental regulatory gene and of the developmentally regulated awh11 gene. Controls the expression of the catalase-peroxidase gene cpeA. Plays an important role in cell wall biogenesis during the development by controlling the transcription level of fksA.
Subcellular location: Nucleus {ECO:0000269|PubMed:25550299, ECO:0000269|PubMed:9379904}.
Interaction partners:
- C2H2 type master regulator of conidiophore development brlA
- Conidiophore development regulator abaA
- cAMP-dependent protein kinase
- rRNA-processing protein efg1
- cAMP-dependent protein kinase
- Developmental regulatory protein wetA
- Protein-methionine methyltransferase laeA
- DNA-binding protein creA
- C2H2-type domain-containing protein
Sequence:
MASMNQPQPYMDVHSHLSSGQTYASHPATAGALTHYQYPQQPPVLQPTSTYGPASSYSQYPYPNSVASSQSVPPPTTSISSQVPAQLLPLPVTNHPVPTHGYGNNSGTPMQGYVYDPTGQMAPPGAKPRVTATLWEDEGSLCYQVEAKGVCVARREDNGMINGTKLLNVAGMTRGRRDGILKSEKVRNVVKIGPMHLKGVWIPFDRALEFANKEKITDLLYPLFVQHISNLLYHPANQNQRNMTVPDSRRLEGPQPVVRTPQAQQPPSLHHHSLQTPVPSHMSQPGGRPSLDRAHTFPTPPASASSLIGITSQNNSYDWNPGMNSSVPNTQPLSIDTSLSNARSMPTTPATTPPGNNLQGMQSYQPQSGYDSKPYYSAAPSTHPQYAPQQPLPQQSMAQYGHSMPTSSYRDMAPPSSQRGSVTEIESDVKTERYGQGTVAKTEPEQEQEYAQPDSGYNTGRGSYYTTNPSVGGLAHDHSQLTPDMTGSPQQNGSGRMTPRTSNTAPQWAPGYTTPPRPAAASSLYNIVSDTRGTSGANGSTSDNYSVASNSGYSTGMNGSMGSNKRMRDDDDDRIVPPDSRGEFDTKRRKTLTETPVGGPVGGVPLGLQPMKAGGSLISARR
Protein: Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage-inducible transcript 1 protein) (DDIT-1) (P48316)
Organism: Mus musculus (Mouse)
Function: Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase 4
- Cyclin-dependent kinase 1
- Cellular tumor antigen p53
- G2/mitotic-specific cyclin-B1
- G/T mismatch-specific thymine DNA glycosylase
- Proliferating cell nuclear antigen
- Growth arrest and DNA damage-inducible protein GADD45 beta
- Methylcytosine dioxygenase TET1
- Aurora kinase A
- G2/mitotic-specific cyclin-B2
Sequence:
MTLEEFSAAEQKTERMDTVGDALEEVLSKARSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIRAFCCENDINILRVSNPGRLAELLLLENDAGPAESGGAAQTPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
Protein: Acyltransferase (EC 2.3.1.-) (Q23067)
Organism: Caenorhabditis elegans
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367023}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367023}.
Interaction partners:
- Uncharacterized protein
- O-acyltransferase
- Phospholipid phosphatase homolog 1.2 homolog
- LNS2/PITP domain-containing protein
- Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
- Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
- Acyltransferase
- Diacylglycerol kinase
- Putative diacylglycerol kinase K06A1.6
- Probable diacylglycerol kinase 3
Sequence:
MRLRLSSISGKAKLPDKEICSSVSRILAPLLVPWKRRLETLAVMGFIFMWVILPIMDLWVPFHVLFNTRWWFLVPLYAVWFYYDFDTPKKASRRWNWARRHVAWKYFASYFPLRLIKTADLPADRNYIIGSHPHGMFSVGGFTAMSTNATGFEDKFPGIKSHIMTLNGQFYFPFRREFGIMLGGIEVSKESLEYTLTKCGKGRACAIVIGGASEALEAHPNKNTLTLINRRGFCKYALKFGADLVPMYNFGENDLYEQYENPKGSRLREVQEKIKDMFGLCPPLLRGRSLFNQYLIGLLPFRKPVTTVMGRPIRVTQTDEPTVEQIDELHAKYCDALYNLFEEYKHLHSIPPDTHLIFQ
Protein: DAR GTPase 3, chloroplastic (Protein EMBRYO DEFECTIVE 3129) (Q8H1F6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: GTPase that may function in chloroplast ribosome assembly (Probable).
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Ribosome biogenesis protein BOP1 homolog
- Pescadillo homolog
- Probable rRNA-processing protein EBP2 homolog
- AT5g04600/T32M21_200
- Ribosome biogenesis protein WDR12 homolog
- Ribosome assembly factor mrt4
- Ribosome production factor 2 homolog
- Nuclear/nucleolar GTPase 2
- Probable ribosome biogenesis protein RLP24
- Nucleolar complex-associated protein 3
Sequence:
MFAQLAPSPSPSPANVSHFVHRRTFRQCTYAVSASLPTANSSRPPPIQIVGGKDLNLDVTRKDDSIGFKLEANEDEIDWMNLESDIRLWTRALRPVQWYPGHIMKTEKELREQLKLMDVVIEVRDARIPLSTTHPKMDAWLGNRKRILVLNREDMISNDDRNDWARYFAKQGIKVIFTNGKLGMGAMKLGRLAKSLAGDVNGKRREKGLLPRSVRAGIIGYPNVGKSSLINRLLKRKICAAAPRPGVTREMKWVKLGKDLDLLDSPGMLPMRIDDQAAAIKLAICDDIGEKAYDFTDVAGILVQMLARIPEVGAKALYNRYKIQLEGNCGKKFVKTLGLNLFGGDSHQAAFRILTDFRKGKFGYVSLERPPL
Protein: DNA repair protein RAD59 (Q12223)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA.
Subcellular location: Nucleus.
Interaction partners:
- DNA repair and recombination protein RAD52
- DNA repair protein RAD51
- DNA repair protein RAD57
- DNA repair protein RAD55
- DNA repair and recombination protein RAD54
- Replication factor A protein 1
- ATP-dependent DNA helicase SRS2
- DNA repair and recombination protein RDH54
- ATP-dependent helicase SGS1
- Replication factor A protein 2
Sequence:
MTIQAKPSSSISYDSTTYGTAPGLDIKEFQIIEDWNGRPASAWSVQRIGLLQSKIERYTYNIYHNNKYGKHNLSKLIPGHALIQFANETFGYDGWRMDVIDVEARECQPFTAVNNGENTNTSEVKYTVVAEAQVKVTLKDGTNTQCGGLGRITLSSRGECYNRSKKEAVGDALKKALLSFEKIILDYETKITNNYYVDGLYGSKKIKNEANTNYNLLSATNSKPTFIKLEDAKGTHIK
Protein: Mucoidy inhibitor MuiA (Q9I3L8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- DUF541 domain-containing protein
- Probable sigma-70 factor, ECF subfamily
Sequence:
MNRLAASPLLFAGLFASAPLLAAPQAVDSRISAVTVYADRAVVTRTARLQLPKGQHEIALEQLPFQLDDASLRASLGASAAATLLDVSSAAQRVERPDDNRVQQLDQQLREIDRQLREIHDRGSVLEAQKKFLADIQSGSTQPGKDRPMPGIDELKSLLQLTEGNLERLLAEQRQLDDRAAELEQRKQQLQEQRGTLNGDGKRFKRAVLRVALEQPAQVEVKLDYTLRDASWQPTYDARLRDGAKTIELTYQGLVRQSSGEDWTDVDLTLSTARPALGGNVPRLNPWIVDIDAPNAYYGAEMAMQDVPAPMPQAAPIARTSAKMAMPAPAPKLAEARLATAEVSSGAASASFHIPVPATLNSDGSAQKVTIARLEMPAKLRYLAAPALRETAYLEAETRNDSDYPLLPGTLNTFLGNSFVASGHLRGVMPGESFELALGADEGIGIERKLVKRYTDSSGLIGNRTRVNYEFRIDVRNNHKNAERVQFEDQLPVSRNEQIQVTLLEPKAQEVKREDDGKLKWDWTLQPGEKRSATLKFSVEYPKDLAVSGLD
Protein: General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit) (Q13889)
Organism: Homo sapiens (Human)
Function: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Subcellular location: Nucleus {ECO:0000269|PubMed:27193682, ECO:0000269|PubMed:9852112}.
Interaction partners:
- General transcription factor IIH subunit 5
- General transcription factor IIH subunit 2-like protein
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- Cyclin-dependent kinase 7
- Cyclin-H
- General transcription factor IIE subunit 1
- General transcription factor IIH subunit 4
- Transcription initiation factor IIE subunit beta
- CDK-activating kinase assembly factor MAT1
- General transcription and DNA repair factor IIH helicase subunit XPD
Sequence:
MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKVSA
Protein: Putative zinc finger protein At1g68190 (Q9C9F4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger protein CONSTANS-LIKE 8
- non-specific serine/threonine protein kinase
- TORTIFOLIA1-like protein 4
- non-specific serine/threonine protein kinase
- Probable mediator of RNA polymerase II transcription subunit 26b
- IQ domain-containing protein IQM3
- Zinc finger protein CONSTANS-LIKE 7
- Auxin-responsive protein SAUR27
Sequence:
MLCIIIIENMERVCEFCKAYRAVVYCIADTANLCLTCDAKVHSANSLSGRHLRTVLCDSCKNQPCVVRCFDHKMFLCHGCNDKFHGGGSSEHRRRDLRCYTGCPPAKDFAVMWGFRVMDDDDDVSLEQSFRMVKPKVQREGGFILEQILELEKVQLREENGSSSLTERGDPSPLELPKKPEEQLIDLPQTGKELVVDFSHLSSSSTLGDSFWECKSPYNKNNQLWHQNIQDIGVCEDTICSDDDFQIPDIDLTFRNFEEQFGADPEPIADSNNVFFVSSLDKSHEMKTFSSSFNNPIFAPKPASSTISFSSSETDNPYSHSEEVISFCPSLSNNTRQKVITRLKEKKRARVEEKKA
Protein: DNA topoisomerase I (EC 5.6.2.1) (DNA topoisomerase 1) (Q581U8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA topoisomerase type IB small subunit
- Small ubiquitin protein, putative
- DNA topoisomerase 2
- Tyrosyl-DNA Phosphodiesterase
- SUMO-conjugating enzyme UBC9
- DNA topoisomerase 2
Sequence:
MTEKKIKKVVIKEEENELEMVAAGMGPAKGAVKREGDENKAALLANEEGGGNDGETEWWTQGTLTTTKKGEKRWDTLLHNGVLFPPAYVPHGIPILYNQQKFEMTPEEEEVATMFAVLREHDYYRNEVFRRNFFQSWREILDKRKHPIRCLELCDFSAIYEWHQREVEKRKSRTREEKKELKRIADEEAEPYKWCIWNGKKEQVANFRVEPPGLFRGRGEHPMRGKLKKRILPEDVVLNIGKEAPIPQAPAGHKWKGVVHDQNVTWLAMWYEPTIGQCKYVMLAPSSTLKGQSDYAKFETARELKNHIDDIRESYTKDFSSTDEMERQRAVATYFIDKLALRVGHEKGEEEADTVGCCSLRKEHIELRPDNVVRFDFLGKDSIRYVNEVTVLPEVYKLLGSFIKRTDSEIFRKVTPTTLNNYLKSFLKDLSAKVFRTYNASITLDEWFREKPVDPKASLSDKLVYFNKANTEVAKLCNHQRSIPKTFHVSVQSIKYKLEDIKRTIDTLRRAQSVSENGSVEEAATQFFKEQDEVQYQWLNTYGTPEEIQAYEEFVKKRVIPTALTGSASSTKNKSGKKTANGKSKKSGGAKRSTKKASGTKKKKTRSKKSAAKTGKKASGKKKKQKKRGGSKRGSRGKNGAGAASGDENDEDAPLVNIIAK
Protein: FG-GAP repeat protein, putative (Q381H5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRLRDVFIVGVAIIFCIFGWHQEDGLAVWKGFEIPITDLESQRYMIPKPVVLDPMGDGRPVLIATTSYGSLEMFKTHSTSGAAETYATPVSMYQRSFFSRITAIGAGRLAVGEDYAIFVVTSDFLLYRLSPHDFSEVWSVPIHNVLSESFHTSVSVLSERIYEGDEGTVVIATQVPGPNHTKLMLFAAFNGADGKLRWRYTSDAESSVREVLDPEDAVGVGGSSPSGASVVVSSQATESFRLYEKPWTFYREAVSTLLPHRYSHPWDECLRPHVFFHTKNRKKTKAQAGNTVVVKYKDRFVRMNSEDYGELAERLGLVSKPQKKGSSHGEKERKSANVLAFHGEHGIEVVHLYTGNLITRVAPLKSAGVYYHDINDDFEIDAVSTLIGRRMEKHSHFDVDVTLDCLGVISTGAPAADHSLFQTSICNTEGIFGRLELIHRFIDGDTRGEGTPEVLSALELVGSHNTLSHTTKSVTPLVVQLHTLRGRGLFQVERLAVFMTDSGLVTCVDPSRRRVVWRSQTESSFWRLRSEREADVGEAASSETEHKQRTFPFPHLASYNFYQVNEDTVGHVGGPGRYLRVDPYIVAVGERKLTILSSRTGRVMRVVELEEPAVAPVIVQDFNGDGINDIIVVTEGGIYGFVIGTRTSSDTVTALMILMVGLLVVLFVVRQLGGGVWSEDDILPTTTQDLYRMAKRKSGRATD
Protein: Eisosome protein 1 (Q05050)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for normal formation of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on plasma membrane and mark the site of endocytosis.
Subcellular location: Cytoplasmic granule. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at the eisosomes.
Interaction partners:
- Uncharacterized protein YGR130C
- Eisosome protein SEG1
- Sphingolipid long chain base-responsive protein LSP1
- Sphingolipid long chain base-responsive protein PIL1
- Meiotic sister-chromatid recombination protein 3
- Eisosome protein SEG2
Sequence:
MSLISAVEDRDIHNIGKTSGGGSRTSSITSSKKSLKHGSKSLRKPKVYQTTGEPLSREALYKAKLKYGVYQSPAQSYSIGVSDAHAASDKAANLAHDNQTTVEAYKRMFIDPNATKAASKMGPKVVRNNSITSATSKTSKESQTKRKSKESPGAAASKAYSMTMETTSLSSQTNSRSYSITSASSVLSGASGSFNSTVNPKPKTLNLEKVLVGAEKKAESRIKERWEPEKTNFQYGVKTDEHGNLNQFSFSNEMMNNIMAKVDAPKAQDLQKVKKVSAEKEAKSMKFALGAANAVKDMHPGEDIDKSIALKAQKRETYLSQLTSQQVLTLARANVDRQLDIIEKSDMHRKLFTNMEYNKAAVAVAQSNHQKKTEFHNKINMGGGLFLSPEDITKIASGLISPVLGEVSERAEAQRAMDEEIAERTEAYNKSSNEWETMERSIISNDAKVLTTTANRHQTEKKTSQEKIKASFDALVARMDTKVAERETLLEDTKSKEIEFKKQMQQELKDEKARLDQDLEEWGKKCEQDITEARKEQEELLKPYHDDLANAEAEHKTLVEERDEINAEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKLLELGQTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSELNATEIELKKEKLNLLEAMKDVASARGDDKIDEEKVKKLIGMTSEEYLTQNKSVEKNVEDLPTQLEKIEEGDELKKEEIVGAETKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKISIGNKSSGKEDANDCKSAEHSKEISVSQKAGNNKSLGVSPDSLEHTFSGFSQGSSIEDDQDAISNQEKK
Protein: Capsid vertex component 2 (P16726)
Organism: Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Function: Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04025}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04025}.
Interaction partners:
Sequence:
MSLLHTFWRLPVAVFFEPHEENVLRCPERVLRRLLEDAAVTMRGGGWREDVLMDRVRKRYLRQELRDLGHRVQTYCEDLEGRVSEAEALLNQQCELDEGPSPRTLLQPPCRPRSSSPGTGVAGASAVPHGLYSRHDAITGPAAAPSDVVAPSDAVAASAAAGASSTWLAQCAERPLPGNVPSYFGITQNDPFIRFHTDFRGEVVNTMFENASTWTFSFGIWYYRLKRGLYTQPRWKRVYHLAQMDNFSISQELLLGVVNALENVTVYPTYDCVLSDLEAAACLLAAYGHALWEGRDPPDSVATVLGELPQLLPRLADDVSREIAAWEGPVAAGNNYYAYRDSPDLRYYMPLSGGRHYHPGTFDRHVLVRLFHKRGVIQHLPGYGTITEELVQERLSGQVRDDVLSLWSRRLLVGKLGRDVPVFVHEQQYLRSGLTCLAGLLLLWKVTNADSVFAPRTGKFTLADLLGSDAVAGGGLPGGRAGGEEEGYGGRHGRVRNFEFLVRYYIGPWYARDPAVTLSQLFPGLALLAVTESVRSGWDPSRREDSAGGGDGGGAVLMQLSKSNPVADYMFAQSSKQYGDLRRLEVHDALLFHYEHGLGRLLSVTLPRHRVSTLGSSLFNVNDIYELLYFLVLGFLPSVAVL
Protein: Uncharacterized RNA pseudouridine synthase HP_0347 (EC 5.4.99.-) (RNA pseudouridylate synthase) (RNA-uridine isomerase) (O25114)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Interaction partners:
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein bL17
- RNA 2-O ribose methyltransferase substrate binding domain-containing protein
- Large ribosomal subunit protein uL15
- Ribosomal silencing factor RsfS
- Large ribosomal subunit protein bL21
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL13
Sequence:
MPFVEEEFEILKPTKALFFVRDVLKCSLKEAQRHLDKQRLKQNQQAVRKSQIIQGVVRLIHFKPNEKTQALVFETKDFGVFDKPHQVYTHPKGYFYHESLLDCIQSHFGKNAHPAHRLDYETSGLVLAGKTLQSVKDLKALFMQKKVKKTYLALAHGLVEKSMKIDKPILTPQNIQKDLHIRSKISPLGKQSITLVEPLSYNPFLDISLLKITPLTGRTHQIRLHLSSVDHRIVGEGLYGVADENAREYLQLKRENNAPLLMLHAASLEFEFKGAIYKIASPMPERFMPFLKDLSFFY
Protein: Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4) (O35353)
Organism: Rattus norvegicus (Rat)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Interaction partners:
- Adhesion G protein-coupled receptor L2
- Adhesion G protein-coupled receptor L3
- Guanine nucleotide-binding protein subunit gamma
- Adhesion G protein-coupled receptor L1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit gamma
- G protein subunit alpha transducin 1
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein G
Sequence:
MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
Protein: SAGA-associated factor 11 (N1NXA6)
Organism: Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast)
Subcellular location: Nucleus {ECO:0000256|HAMAP-Rule:MF_03047, ECO:0000256|RuleBase:RU261113}.
Interaction partners:
Sequence:
MTEETITIDSISNGILNNLLTTLIQDIVARETTQQQLLKTRYPDLRSYYFDPNGSLDINGLQKQQESSQYIHCENCGRDVSANRLAAHLQRCLSRGARR
Protein: Eggcase silk protein (C5H5C9)
Organism: Trichonephila antipodiana
Interaction partners:
Sequence:
MVWLTSIAFIVTLLGAQYDIVTAQAISVATSVPSVFSSPSLASGFLGCLTTGIGQSPDFPFQEQQDLDDLAQVILSAVTSNTDTSKSARAQALSTALASSLADLLISESSGSSYQTQISALTNILSDCFVTTTGSNNPAFVSRVQTLIAVLSQSSSNAISGATGGSAFAQSQAFQQSASQSAGLSASRAGSTSSSTTTTTSGATSQAASQSASSSYSSAFAQAASSALATSSAISRAFASVSSASAASSLAYNIGLSAARSLGIASDTALAGALAQAVGGVGAGASASAYANAIARAAGQFLATQGVLNAGNASALAGSFARALSASAESQSFAQSQAYQQAS