wanglab/gogpt-training-data huggingface dataset:
Protein: Vacuolar protein sorting-associated protein 39 homolog (Q9VEA2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q96JC1}. Lysosome membrane {ECO:0000250|UniProtKB:Q96JC1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96JC1}. Late endosome membrane {ECO:0000250|UniProtKB:Q96JC1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96JC1}. Late endosome {ECO:0000250|UniProtKB:Q96JC1}. Lysosome {ECO:0000250|UniProtKB:Q96JC1}.
Interaction partners:
- Vacuolar protein sorting-associated protein 41 homolog
- Vacuolar protein sorting-associated protein 8 homolog
- Vacuolar protein sorting-associated protein 16 homolog
- Vacuolar protein sorting-associated protein 11 homolog
- Vacuolar protein sorting-associated protein 18 homolog
- Vacuolar protein sorting 33B
- Ras-related protein Rab7
- Vacuolar fusion protein CCZ1 homolog
- Syntaxin 17, isoform B
- Vacuolar protein sorting-associated protein 33A
Sequence:
MHQAYSVHSILKQGVQIESIAAYGNHVILGTRSGQLIMYSVDEETGVDMRMFNKNFSRKPITQMEVIASENLLFVLTDLQVQVCDIRRIESNFAFMHSAPDTKGCTLFTMDVDTPKSTTGRVATVIRVCCAIRRRLVFFFWKEDKLNSLELIIELSDVPRTLCWVGHAVCVGFKDEYVVYDISGKAPKKHNLFLTSSSISRDPCICLIRNNMLGISKDSYLVVVDPSQYKESDGINNSTDVRPAAMDSNSSLTPLLWSSPLLDLVWDEPFAVGRVNNAIEVRSLVGKDTLVQTIPELQKTKFLVHADKGTIFAAATSELWCIRMVEIPIQRQQLLQQKKFQLAIELTQISDEPAADRAQTIRQIHMLYAKELFTNKEFSAAMKEFEKAAIDPYDVIRLFPNLVPEPKPGTEDVTVPTSSTPALEDSDLENAYLALIEYLAWARQREVVKLRDTKSSSKSLLEIIDTTLLKCYLQTNDSLVAPLLRLNQCHLEESEKTLKKHNKISELIILYQMKGKHKEALKLLREQASIEGSVLQGRKRTIRYLQELGGDHLPLIFEFADWVLNDNPEEGLTIFTDELIEVESLPRAKVLDFFISKHKALVIPYLEHVITEWKDGNTLLHNVLLKQYREKVQRLLAQQEKGEEVPELIPMRAKLYKMLEESNDYSPDRLLEEFPTNILLEERALILGRLKKHDNVLSIYIHVLGDVAKATAYAEAHYKEDKHIFHTLIKCILIPPTQPLYDGVPLHPDFSQVNREVALEILNTHATRIDPFEIFEHLPDDMPMPQLEKYLEKSIRKMMADKHEMQMMCGFLEAESTRLENALEEQRNISFELNESSVCSECKKRFQTQSAFVRYPNGHIVHLSCHDRLARAAAQQ
Protein: Seminal ribonuclease (S-RNase) (Seminal RNase) (EC 4.6.1.18) (Ribonuclease BS-1) (P00669)
Organism: Bos taurus (Bovine)
Function: This enzyme hydrolyzes both single- and double-stranded RNA.
Subcellular location: Secreted.
Interaction partners:
- Seminal plasma protein PDC-109
Sequence:
MALKSLVVLPLLVLVLLLVRVQPSLGKESAAAKFERQHMDSGNSPSSSSNYCNLMMCCRKMTQGKCKPVNTFVHESLADVKAVCSQKKVTCKNGQTNCYQSKSTMRITDCRETGSSKYPNCAYKTTQVEKHIIVACGGKPSVPVHFDASV
Protein: ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47 homolog) (Protein porthos) (Q9VIF6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Part of a translational control module, also containing ath/DHX33 and ais/DDX52, which coordinates germline stem cell differentiation with ribosome biogenesis during oogenesis. This module allows for coregulation of ribosomal proteins and non1/GTPBP4, a p53 repressor, preventing p53 stabilization, cell cycle arrest and loss of stem cell differentiation. With atos, adjusts transcription and translation of a subset of OXPHOS genes in marophages to increase mitochondrial bioenergetics and allow tissue invasion.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:35319107, ECO:0000269|PubMed:35413237}.
Interaction partners:
- EG:8D8.4 protein
- FI04466p
- LD41718p
- Something about silencing protein 10
- Ribosome biogenesis protein BOP1 homolog
- Probable ATP-dependent RNA helicase DDX52
- Guanine nucleotide-binding protein-like 3 homolog
- Putative rRNA methyltransferase
- rRNA biogenesis protein RRP5
- KRR1 small subunit processome component homolog
Sequence:
MSETSEDEQTQLQTSDEEEDLGSEEEQEDEDNNHKEGDSEAALSGEDDKGSEDDAAEEQKLTWKDLGLNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILHALLENPQRYFALVLTPTRELAFQIGEQFEALGSGIGIKCCVVVGGMDMVAQGLQLAKKPHIIIATPGRLVDHLENMKGFNLKAIKYLVMDEADRILNMDFEVELDKILKVLPRERRTFLFSATMTKKVKKLQRASLKDPVKVEVSNKYQTVEQLQQSYLFIPVKYKDVYLVHILNELAGNSFMIFCSTCNNTVKTALMLRALGLAAIPLHGQMSQNKRLAALNKFKAKNRSILISTDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITLVSQYDIELYQRIEHLLGKQLTLYKCEEDEVMALQERVAEAQRTAKLELKDLEDTRGGHKRGGDTHDDSENFTGARKRMKPMGGTGGGGRKSFGKKNWSKGKQKR
Protein: Thioredoxin-like fold domain-containing protein (Q57TV3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNEGSSRALQGMYREHPLCCAAFAAAACGYAMYRCTKLLQALRKRVMTQVMLNSLEHGIVHLFIHPRWPHGPNCFLHCFKVETFLRLAKISYIVHFIDDPTVSPNGKLPFILYDGVAVGDSEVIIHYLMNEFDVDLDNQLSAESHAVGRVVTRMVETSLNYGLQRVVLIDHPELLEGVLEEEFTRDEESTHKKVEGMRRTLVEVLETTGDYRLPPLEYTRQFLQEVKCLDVLLQKSAFLLGDTPTSYDAVVYAWLHVAKTLMEGHEELIPALAVSEPFASYVARMTSAAFPDMKSISGCNQSHRFTPHTCRQGCS
Protein: F9K20.24 protein (SecY protein transport family protein) (Q9ZV90)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}. Plastid, chloroplast thylakoid membrane {ECO:0000256|ARBA:ARBA00004454}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004454}.
Interaction partners:
- Protein transport protein Sec61 subunit gamma-3
- Protein transport protein Sec61 subunit gamma-1
- Preprotein translocase subunit SCY1, chloroplastic
- Preprotein translocase Sec, Sec61-beta subunit protein
- Protein transport protein Sec61 subunit beta
- Protein transport protein Sec61 subunit beta
- Protein transport protein Sec61 subunit gamma-2
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein uL23y
Sequence:
MVGGFRVIHLVRPFLAFLPEVQSPERKIPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFYWMRVILASSRGTVMELGITPIVTSGMVMQLLAGSKIIEIDNNVREDRALLNGAQKLLGILIAVGQAVAYVLSGMYGSVGELGVGNAILIIVQLCFAAIIVLCLDELLQKGYGLGSGISLFIATNICESIIWKAFSPTTINSGRGAQFEGAVIALFHLLITRTDKVRALREAFFRQNLPNVTNLHATVLIFLIVIYFQGFRVVLPVRSKNARGQRGSYPIKLFYTSNMPIILQSALVSNIYFISQILYRKFGGNFLVNLIGTWKESEYSGQSIPVGGIAYYITAPSSLAEMATHPFHALFYLVFMLAACALFSKTWIEVSGSSAKDVARQLREQQMVMPGHRDSNLQKELNRYIPTAAAFGGLCIGALTVLADLMGAIGSGTGILLAVTIIYQYFETFEKEKASELGFFGL
Protein: Integrin alpha-E (Integrin alpha M290) (CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain] (Q60677)
Organism: Mus musculus (Mouse)
Function: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Integrin beta-7
- Cadherin-1
- T-cell surface glycoprotein CD4
- Forkhead box protein P3
- Early activation antigen CD69
- Integrin beta-1
- Basic leucine zipper transcriptional factor ATF-like 3
- Receptor-type tyrosine-protein phosphatase C
- L-selectin
- C-C chemokine receptor type 7
Sequence:
MKWLFHTLLCMASLKPQGAFNLDVDWAWVTALQPGAPAVLSSLLHQDPSNNQTCLLVARRSSNRNTAALYRCAISISPDEIACQPVEHICMPKGRYQGVTLVGNHNGVLVCIQVQARKFRSLNSELTGACSLLTPNLDLQAQAYFSDLEGFLDPGAHVDSGDYCRSKGGSTGEEKKSARRRRTVEEEDEEEDGTEIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGAVIQTEFDLQESRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFGDPLNLTTVINSPKMQGVVRFAIGVGDAFKNNNTYRELKLIASDPKEAHTFKVTNYSALDGLLSKLQQHIVHMEGTVGDALQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALLYSTQNGRGCFLNQTAKEDSRTVQYSYLGYSLAVLHKAHGVSYVAGAPRHKLRGAVFELRKEDREEDAFVRRIEGEQMGSYFGSVLCPVDIDMDGTTDFLLVAAPFYHIRGEEGRVYVYQVPEQDASFSLAHTLSGHPGLTNSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLYDSPSQQIRASSVASGLHYFGMSVSGGLDFNGDGLADITVGSRDSAVVLRSRPVVDLTVSMTFTPDALPMVFIGKMDVKLCFEVDSSGVASEPGLREMFLNFTVDVDVTKQRQRLQCEDSSGCQSCLRKWNGGSFLCEHFWLISTEELCEEDCFSNITIKVTYEFQTSGGRRDYPNPTLDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTNISQQELVVGVTKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPVSPDVQCDDPKPVASVLVMNCKIGHPILKRSSVNVSVTWQLEESVFPNRTADITVTISNSNEKSLARETRSLQFRHAFIAVLSRPSVMYMNTSQSPSDHKEFFFNVHGENLFGAVFQLQICVPIKLQDFQIVRVKNLTKTQDHTECTQSQEPACGSDPVQHVKEWHSVVCAITSNKENVTVAAEISVGHTKQLLRDVSELPILGEISFNKSLYEGLNAENHRTKITVIFLKEEETRSLPLIIGSSIGGLLVLVVIIAILFKCGFFKRKYQQLNLESTRRAQLKADSLLQD
Protein: N-formylglutamate deformylase (EC 3.5.1.68) (N-formyl-L-glutamate deformylase) (Q9HU92)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Catalyzes the hydrolysis of N-formyl-L-glutamate to formate and L-glutamate. Shows weak activity with N-formyl-L-glutamine.
Interaction partners:
- Formimidoylglutamate deiminase
- Imidazolonepropionase
- Formimidoylglutamase
- Probable histidine/phenylalanine ammonia-lyase
- Probable permease of ABC transporter
- Quaternary amine transport ATP-binding protein
- Histidine ammonia-lyase
- Probable binding protein component of ABC transporter
- Urocanate hydratase
- Formate dehydrogenase iron-sulfur subunit
Sequence:
MDEVLSFKRGRVPLLISMPHPGTRLTPAVDAGLVEEARALTDTDWHIPRLYDFAEELGASTLAAHYSRYVVDLNRPSDDKPLYSTATTGLYPDTLFDGRPLYREGMAPSAEERMRYLAEVWTPYHRTIAEELARLKAEFGYALLWDAHSIRSHVPHLFDGRLPDFNLGTNAGASCDPALAARLEAVCAAAEGYSHVLNGRFKGGHITRHYGQPEQHVHAVQLELAQCTYMDEQAPFAYRADLAEATRAVIRELLESLLAWGRERYA
Protein: E2F/DP family winged-helix DNA-binding domain-containing protein (EFL-1) (G5EF11)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU003796}.
Interaction partners:
- Retinoblastoma-like protein homolog lin-35
- Transcription factor dpl-1
- Protein lin-9
- Protein lin-54
- Protein lin-52
- Uncharacterized protein
- E2F_TDP domain-containing protein.
- Dwarfin sma.
- Dwarfin sma-4
- Probable histone-binding protein lin-53
Sequence:
MEDSYNDMEDPGFRQLSDMELQKALEMTKQSSIKNNLMLGLDNELDFDFDFDEDEDLDQPQMGTRADKSLGLLAKRFIRMIQYSPYGRCDLNTAAEALNVRQKRRIYDITNVLEGIGLIEKRSKNMIQWKGGDFMLNVKEGKRQSATTEEEDRMEQLKAEIEQLNKEEELIEQRQRWLQQSLRNMTESVENNKLSYVLRSQLAEIQGSDLTIGIQTRVGTQVRLSDPEQVEIHGGPSWCYLKDPSGPLRAAIVSNHELHDFVQRERAKRPGEEHVDADAPDEMMDDSRYRNRRTINDDEMFGFEQKVPAMKHLEPPPASDDYVYSSTGDEYRGDSIVDLYGD
Protein: Complement C2 (EC 3.4.21.43) (C3/C5 convertase) (A0A8J8XKZ6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MTFSLPWLSRSTVLETMAPLLALLALLQLGPGLAALSCPQNVNIVGGNFTLSRGWAPGSVLIYSCPLGRYPSPAWRECQSNGQWQTPRASSLPTLRSSRLAKAVCKPVRCPAPTSFENGIYIPRLGSYPVGGNLSFECEHGFTLRGSPVRYCRPNGVWDGETAVCDNGASHCPNPGISVGTMRTGSSFDLGDKVSYRCSSTNLVLTGSVERECLSNGVWSGSEPICRQPYSYDFPEDVASALGTSFTHLLGATNPIQKRTENLGRKIQIQRSGHLNLYLLLDASQSVSEKDFNIFKESAFLMVDRIFSFEIKVSVAIITFASRPKIIMSVLNERSQNVMEVMDSLDSVCYKDHENATGTNTYEALNSVYLMMNNQMDRLGMETSAWQEIRHAIILLTDGKSNMGGSPKPAVDNIREILGISRNRNDYLDIYAIGVGKLDVDWKELNELGSKKDGERHAFILQDAKAVQQVFEHILDVSKLTDTICGVGNMSVNASDQERTPWQVTFKPKSKETCQGSLISDQWVLTAAHCFHDAQMEDRHLWRVIVGDPTSHHGKEFHVEEVLVAPGFNVHAKQSQGISEFYADDIALLKLSQRVKMSSHARPICLPCTVGANMALRRSPGSTCKDHETELLSQQKVPAHFVALNGNRMNINLRTGPERTSCIEAVSQNKGSFPGLTNVSEVVTDQFLCSGMEGDDSPCKGESGGAVFLERRYRFFQVGLVSWGLFDPCHGSSNKNLRRKPPHGVVPRDFHISLFRLQPWLRQHLDGVLDFLPL
Protein: Protein turtle (Q967D7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Essential protein that plays a role in the establishment of coordinated motor control. In the developing eye, involved in axonal targeting of the R7 photoreceptor.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MGVCADLGSHRWCRALSTQHNTEKSKEQQQQSQPLEIPEQRASKCRGDIDRTTTTTIPASKTLTASPAKTAAFTVKTTRRRRSRRRAEGSSICVPIRRGQGSTPTPTIQVLQFVLVSLLALLAKNAQAHNIPEDAVHITAILGEGVIFNCHVEFPNDHPVPYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATLMAVTQLVIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAPAAPRNVKAATQPPDSFFQLMPDEAGPKPGPPRNVSVTEVSNGFLITWQSPLERAHIVKFYTIKYRTDAQWKTLNRGQIRPEETQYLVKNLVGGRTYYFRVLANSEKSYESSDEVKFPVPARVKHKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQEKEFNMVACRITDARNIAANNHHLHNRSTGSISSGQVPLKNNTEHYRDYESVFIVPGHPVIIKIVQTNPNIKSNRHSHCHLHWIWPPDRCTNCHSIYSSPNLEDGDEDDGGGGRRRSVSRIQRSLDGRFVLDVEGVSKLGYSQQTLESGNVDVVDGGLFERRNSNVSQKSSSDDGGFLSRRNFITARASWRRPLVASSSQLSLQSAADSARGFLQGLLKIGAKQSAVPPNSQSYFDEAVSGARYQNVLRPYTSSNNLYGNADRSRPLHINTISGSLSQQQQLYTPSRISRIFSSSPQQLQPHHQQLLLSSGGSGAYPTHFSDLSTVYPPNSAERSSHNLSSRYRYYSQELPSLRTIQEETRRQQQQKQHPLEDHFVPLQLPSPPSWRSYYQSQASYRPRTRWYPRHHSRLFSNRQQQHEMLSPLPQLNLNLRNSMNPGGLEASPESRSSSSGFGSKNTSNHPGSTSEWRLLPPYRAPPSPPKHSGYFGGQQAQGQTPHGSYSYPRATTPPYTMAHWLEMISRLNAATDSNLPKAPCPVDVGSVDGHYEFDPATPTPSASSMLREDLNLHIDTHPYHHHTLGPLSGSLLHSHAPYGGGARKQRSLPAHLPRYDNVEVRLQAMREEFYAYRKRQAMQQMESVC
Protein: Cysteine and glycine-rich protein 3 (cardiac LIM protein) (Cysteine and glycine-rich protein 3 isoform 2) (F1QJC0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Telethonin
- Myozenin 2
- Titin, tandem duplicate 1.
- Actinin alpha 3b
- Myosin-binding protein C, cardiac-type
- Myosin regulatory light chain 2b
- Uncharacterized protein.
- Troponin T type 2a
- Tropomyosin 1
- Tropomyosin alpha-1 chain
Sequence:
MPNWGGGAKCAACEKTVYHAEEIQCNSRSFHKTCFICMVCRKGLDSTTVAAHESEIYCKTCYGKKYGPKGYGYGQGAGALSSDPVNNEELQPQEPKAPRPAPANSNSSKFAQKFGSTDRCPRCSKAVYAAEKIMGAGKPWHKTCFRCLLCGKSLESTTVTDKDGELYCKVCYAKNFGPKGRGLGNPGMVEESV
Protein: Beta-lactamase (EC 3.5.2.6) (Cephalosporinase) (P24735)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Periplasm {ECO:0000250|UniProtKB:P85302}.
Interaction partners:
- HTH-type transcriptional activator AmpR
- Ribosomal protein S3AE
- Beta-hexosaminidase
- Peptidoglycan D,D-transpeptidase FtsI
- DNA gyrase subunit A
- 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
- AmpG
- N-acetylmuramoyl-L-alanine amidase
- N-acetylmuramoyl-L-alanine amidase
- Multidrug resistance protein MexB
Sequence:
MRDTRFPCLCGIAASTLLFATTPAIAGEAPADRLKALVDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERVKIAYAILSGLEQQGKVPLKR
Protein: Actin-binding LIM protein 1 (A0A0G2JW01)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPPNIPRSSSDFFYPKSLIRRTGRSPALQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQDRQSLGESPRTLSPTPSAEGFQDGRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPDQGINIYRKPPIYKQHAALAAQNKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAIGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKENRERASLLASRYDSPLHSASHAPSSKTSSLPGYGKSGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF
Protein: Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG7 (EC 3.2.2.n1) (Protein LONELY GUY 7) (Q8GW29)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19837870}. Nucleus {ECO:0000269|PubMed:19837870}.
Interaction partners:
- Putative dynamin-related protein 4A
- Adenylate isopentenyltransferase 7, mitochondrial
- ABC transporter G family member 14
- Adenylate isopentenyltransferase 3, chloroplastic
- Cytokinin dehydrogenase 3
- Cytokinin hydroxylase
- Cytokinin dehydrogenase 5
- Cytokinin dehydrogenase 7
- Histidine kinase 3
- Cytokinin dehydrogenase 1
Sequence:
MEETKSRFKRICVFCGSSSGKKPSYQEAAIQLGNELVERRIDLVYGGGSVGLMGLVSQAVHHGGRHVLGVIPKTLMPREITGETIGEVKAVADMHQRKAEMARQADAFIALPGGYGTLEELLEVITWAQLGIHRKPVGLLNVDGYYNSLLTFIDKAVDEGFISPMARRIIVSAPNAKELVRQLEEYEPEFDEITSKLVWDEVDRISYVPGSEVATAT
Protein: ABC-type transport system, ATPase component, involved in antimicrobial peptide resistance (Q4QL77)
Organism: Haemophilus influenzae (strain 86-028NP)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004417}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004417}.
Interaction partners:
Sequence:
MPLLQVEDLTKTFKGHASLFGRNQFNAVDKVSFTLERKQTLAIIGNNGSGKSTLVKMIAGIIPPTSGRILFNDRELQYQDAQSRAKHIRMVFQDANSAFNPRLNIGQILDEPLSLATDWTETQRNEKIFETLSLVGLYPDYTNLNIKHLSISQKQRVALARALILAPEIIIIDDAIGNLDASVRIQLLNLTLDLQQRLGISYIYVGQDLGVIKHIADTIIVMDDGKMIEYGSPQNLFTDPQTDVTRRLVESYFGKILDETAWVKDKNTH
Protein: Os01g0288200 protein (cDNA clone:001-111-G01, full insert sequence) (Q5NB08)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MAGSWVRTITSPFRKVFGAQPHKDGGKRPQQPNSGMMVQHVVVDAERSKLHGEVMACAYEDVQVMWDMLDKARIREFNSS
Protein: Uncharacterized protein (Q38D89)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAAKRSGSAGASPIQLLQPLEPNKKYIKRMKTLAKKREAAAEEERRHNKRLRMNDKKRKQASERAHGKGGKKAILTEKGRKPVKGSTKKSERKPVKEKAGQKKDKKVAVALPNKKKVERLRDISVPFELPPPSQEEIDKQLLQRVIGGEDGKRDSTSADAPGGGGFNSPHLPFLDDYAQQKRSEIVEADGLLQKAHSYFKDLSKRECQLRRAAAKRLRELKEINKRGGDKDGFRYVVPRNVSEVVRQMTQGADVDPTQLVSTFGAEDDKLRSQEEHLHEASDRPMHRRKRKNPCYSDFYQFQVSKRWTRNAERFLEKGRAHKSMFEASKQRRSLKKF
Protein: Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein) (Q9Y3A2)
Organism: Homo sapiens (Human)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:34516797}.
Interaction partners:
- Something about silencing protein 10
- rRNA-processing protein FCF1 homolog
- U3 small nucleolar RNA-associated protein 18 homolog
- WD repeat-containing protein 46
- KRR1 small subunit processome component homolog
- Neuroguidin
- Small subunit processome component 20 homolog
- WD repeat-containing protein 36
- Deoxynucleotidyltransferase terminal-interacting protein 2
- U3 small nucleolar ribonucleoprotein protein MPP10
Sequence:
MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRKR
Protein: Suppressor of hairless protein homolog (CSL transcription factor lag-1) (Lin-12 and glp-1 phenotype protein) (V6CLJ5)
Organism: Caenorhabditis elegans
Function: Transcriptional regulator that plays a central role in lin-12/Notch and glp-1/Notch signaling pathways, involved in cell-cell communication that regulate a broad spectrum of cell-fate determinations. Binds directly to the 5'-[A/G]TGGGAA-3' DNA consensus sequence, which is present in the regulatory region of several genes. Acts as a transcriptional repressor when it is not associated with Notch proteins (By similarity). When in a complex with a Notch intracellular domain (NICD) product of lin-12/Notch or glp-1/Notch, and transcription regulator lag-3, it may act as a transcriptional activator that activates transcription of target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively (By similarity). Autonomously required in the germline for the stem cell fate, acting in the glp-1-dependent transcriptional activation of genes, including lst-1 and sygl-1. Involved in cell-fate specification during reproductive system development, by positively autoregulating its own expression, in response to lin-12/Notch signaling. Plays a role in Notch-dependent induction of left-right asymmetry in interneurons and motoneurons. May repress expression of hlh-6, in a lin-12/Notch-independent manner.
Subcellular location: Nucleus {ECO:0000269|PubMed:32196486}.
Interaction partners:
- Protein lag-3
- Protein lin-12
- CBF1-interacting co-repressor CIR N-terminal domain-containing protein
- C-terminal-binding protein 1
- Protein glp-1
- Histone deacetylase 1
- histone acetyltransferase
- Putative histone deacetylase 2
- Histone deacetylase
- Uncharacterized protein T27F2.1
Sequence:
MFSWRRGDCESQKEENRSEERKGEETIRFPTRSPFHCVLFLLTDGFVLHKPTASPTVGFSPTIFSFYYSRWESSHRISHDESGFCTAKTPLQDSTFTRHPSTSVPSSPSTPRHSGMDYHQSSSVASSESTASTVAAAAAAAAAASLNQHHHPHLYCDDGLLSRSLTDMVSSGGYDSSSSSLSAAASMCYPTPDAYYYHAPPPPPPPQAQQGFSSTDAWLQMQMQPTYHNFGSTVVSTNSPLPSHLLSYGGQPAFADPFYTIGQSTPNTSSFLDTSNSSFGAPSTVVANPMTNYQLAFQAKLGSLHSLIGDSVQSLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKRFFCPPPCIYLIGQGWKLKKDRVAQLYKTLKASAQKDAAIENDPIHEQQATELVAYIGIGSDTSERQQLDFSTGKVRHPGDQRQDPNIYDYCAAKTLYISDSDKRKYFDLNAQFFYGCGMEIGGFVSQRIKVISKPSKKKQSMKNTDCKYLCIASGTKVALFNRLRSQTVSTRYLHVEGNAFHASSTKWGAFTIHLFDDERGLQETDNFAVRDGFVYYGSVVKLVDSVTGIALPRLRIRKVDKQQVILDASCSEEPVSQLHKCAFQMIDNELVYLCLSHDKIIQHQATAINEHRHQINDGAAWTIISTDKAEYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGRDFKPNLKVWFGATPVETTFRSEESLHCSIPPVSQVRNEQTHWMFTNRTTGDVEVPISLVRDDGVVYSSGLTFSYKSLERHGPCRIVSNY
Protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Phosphatase and tensin homolog) (Q6PC66)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, dendritic spine {ECO:0000256|ARBA:ARBA00004552}. Cytoplasm {ECO:0000256|PIRNR:PIRNR038025}. Nucleus {ECO:0000256|PIRNR:PIRNR038025}. Nucleus, PML body {ECO:0000256|PIRNR:PIRNR038025}. Postsynaptic density {ECO:0000256|ARBA:ARBA00034105}.
Interaction partners:
Sequence:
MTAKLKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDASKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNKLDYKPVALLFHKMVFQTLPMFSGGTCRDSTVKNRSEVNPQGFKKGSWHWDPQFVVYQLKVKIHTSNPAHTRREEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKDKMFHFWINTFFIPGPEEAGDKVENGSVVNDVDSLSCQSQSSPAERDREKERAVAAAALDRERGGERADGEKDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNSEASTSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEEQHAQITKV
Protein: Lon protease (EC 3.4.21.53) (ATP-dependent protease La) (Q9I2T9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_01973, ECO:0000256|PIRNR:PIRNR001174}.
Interaction partners:
- ATP-dependent Clp protease ATP-binding subunit ClpX
- ATP-dependent Clp protease proteolytic subunit 1
- Chaperone protein DnaK
- Chaperonin GroEL
- ATP-dependent zinc metalloprotease FtsH
- ATP-dependent protease ATPase subunit HslU
- ATP-dependent protease subunit HslV
- ATP-binding protease component ClpA
- Chaperone protein DnaJ
- Polyphosphate kinase
Sequence:
MKTLVELPLLPLRDVVVYPHMVIPLFVGREKSIEALEAAMTGDKQILLLAQKNPADDDPGEDGLYRMGTVATVLQLLKLPDGTVKVLVEGEQRGQVERFIEEEGHIRAAVQAIDDANVGEREAEVFTRSLLSQFEQYVQLGKKVPAEVLSSLNSIDEPSRLVDTMAAHMALKIEQKQDILEITDLSSRVEHVLALLDAEIDLLQVEKRIRGRVKKQMERSQREYYLNEQMKAIQKELGDIDEGHNEVEELKKRIDAAGLTKEAHTKATAELNKLKQMSPMSAEATVVRSYIDWLLNVPWKAESKVRHDLAKAEDILDADHYGLEEVKERILEYLAVQKRVKKLKGPVLCLVGPPGVGKTSLAESIARATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGRLIQKMTKVGVRNPLFLLDEIDKMGSDMRGDPASALLEVLDPEQNHNFNDHYLEVDYDLSDVMFLCTANSMNIPAPLLDRMEVIRLPGYTEDEKVNIAAKYLIPKQVQANGLKKGELTFEEGALRDIIRYYTREAGVRSLERQIAKVCRKAVKEHAKLKRIQAVVSSETLENYLGVRKFRYGLAEQQDQIGQVTGLAWTQVGGELLTIEAAVVPGKGQLTKTGSLGDVMAESITAALTVVRSRAQSLGIAADFHEKRDIHIHVPEGATPKDGPSAGIGMCTALVSAITQIPVRADVAMTGEITLRGQVLAIGGLKEKLLAAHRGGIKTVIIPEENVRDLKEIPDNIKSDLVIKPVKWIDEVLQIALQYAPEPLPDAAPEMVAKDEKREPDSKERISTH