wanglab/gogpt-training-data huggingface dataset:
Protein: Molybdenum cofactor insertion chaperone PaoD (P77183)
Organism: Escherichia coli (strain K12)
Function: Chaperone required for the production of an active PaoABC aldehyde oxidoreductase. Stabilizes the PaoC subunit and is required for the insertion of the molybdenum cofactor into this subunit. Binds molybdenum cofactor. Binds the molybdopterin cytosine dinucleotide (MCD) form of the cofactor after its formation by the molybdenum cofactor cytidylyltransferase MocA.
Interaction partners:
- Aldehyde oxidoreductase FAD-binding subunit PaoB
- Aldehyde oxidoreductase iron-sulfur-binding subunit PaoA
- Aldehyde oxidoreductase molybdenum-binding subunit PaoC
- Putative xanthine dehydrogenase iron-sulfur-binding subunit XdhC
- Probable hypoxanthine oxidase XdhD
- Putative xanthine dehydrogenase FAD-binding subunit XdhB
- Molybdenum cofactor cytidylyltransferase
- Putative xanthine dehydrogenase molybdenum-binding subunit XdhA
Sequence:
MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLVTLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGEGSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPVGLRYDPQAQSLVCLPTQTRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQIDTDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETTQIRAPVGIFPKARDAHTLALSVLAEVASVRLHQEEDSCLPPSS
Protein: Histone-like protein 18C (P16909)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known. Encoded in the intron of cAMP-dependent protein kinase regulatory chain type I.
Interaction partners:
- Protamine A, isoform A
- FI13205p
- Cytosol aminopeptidase
- GH11850p
- CG14926 protein
- Protamine-like protein 99C
- Tubulin beta-2 chain
- Testis-enriched HMG-box-containing protein 1
- IP10875p
- Testis-enriched HMG-box-containing protein 2, isoform B
Sequence:
MSNLKQKDSKPEVAVTKSVKTYKKSIEYVNSDASDIEEDINRAEDEYASSSGFVNFLRDFKKRYGEYYSNNEIRRAAETRWNEMSFRHRCQYSAEPLDTFHVEPNSVSSLQRSSEGEHRMHSEISGCADTFFGAGGSNSCTPRKENKCSKPRVRKSCPKPRAKTSKQRRSCGKPKPKGARPRKACPRPRKKMECGKAKAKPRCLKPKSSKPKCSM
Protein: Angiopoietin-related protein 5 (Angiopoietin-like protein 5) (Q86XS5)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Leukocyte immunoglobulin-like receptor subfamily B member 2
Sequence:
MMSPSQASLLFLNVCIFICGEAVQGNCVHHSTDSSVVNIVEDGSNAKDESKSNDTVCKEDCEESCDVKTKITREEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELMNRVLLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATGIQWGTWTKNNSPVKIKSVSMKIRRMYNPYFK
Protein: Ribonuclease VapC26 (RNase VapC26) (EC 3.1.-.-) (Toxin VapC26) (O53779)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB26.
Interaction partners:
- Antitoxin VapB26
- 23S rRNA-specific endonuclease VapC20
- Ribonuclease VapC4
- Twitching motility protein PilT
- Ribonuclease VapC11
- Ribonuclease VapC25
- Ribonuclease VapC28
- Ribonuclease VapC32
- Ribonuclease VapC29
- Ribonuclease VapC33
Sequence:
MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
Protein: DNA repair protein complementing XP-A cells homolog (Xeroderma pigmentosum group A-complementing protein homolog) (Q64267)
Organism: Mus musculus (Mouse)
Function: Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- DNA excision repair protein ERCC-1
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription and DNA repair factor IIH helicase subunit XPD
- DNA repair endonuclease XPF
- DNA excision repair protein ERCC-5
- UV excision repair protein RAD23 homolog B
- DNA excision repair protein ERCC-6
- DNA damage-binding protein 2
- General transcription factor IIH subunit 3
- Replication protein A 70 kDa DNA-binding subunit
Sequence:
MATAEEKQTSPEPVAADEPAQLPAAVRASVERKRQRALMLRQARLAARPYPAAAATGGVASVKAAPKMIDTKGGFILEEEEEKHEIGNIVHEPGPVMEFDYTICEECGKEFMDSYLMNHFDLPTCDSCRDADDKHKLITKTEAKQEYLLKDCDLEKREPALRFLVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAIRSSVWKRETTTHQHKYGPEENLEDDMYRKTCTLCGHELTYEKM
Protein: B box-type domain-containing protein (Q580C7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDTAAEMYAMREKSQANKNDGDMAETTLGRKCPFAPSDISPFVAMALQDHSAVWDISDVKSPLRRAPAKRKRTESIGKDMNSSVKMEMTTNTVATMAYLLQSGSPLYDPVEKLWRCWNGHELCIKRISDYSGAEEVTCDFCGVTHWCKNKEVRAKPHRLKKLPPEGLLPAEAEPVDETYLYNCSECGMDLCAHCASEVYQDERYHVPCMQCVQCKLFMHDTDGMLHRCQVKRTRVSPSVLHKSPTSTSGCVSSSIQMDSTGSCGVSVGREQSITTQLLPSDVWEVCVAAKNAEEEVRARALATTLFVKETYVPDTVKQLTFRMPTRLAAEELARRGRDAGLCAAVRKSFV
Protein: Protein BEAN1 (Brain-expressed protein associating with Nedd4) (BEAN) (Q9EQG5)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Atypical kinase COQ8A, mitochondrial
Sequence:
MSFKRPCPLARYNRTSYFYPTTFSESSEHSHLLVSPVLVASAVIGVVITLSCITIIVGSIRRDRQARIQRHHHRHRRHHHHHRHRRRRHREYASGGHTHSRSSPRMPYACSPAEDWPPPLDVSSEGDVDVTVLWELYPDSPPGYEECMGPGATQLYVPTDAPPPYSMTDSCPRLNGALDSDSGQSRSHRQQEQRTQGQSRLHTVSMDTLPPYEAVCGTGSPSDLLPLPGPEPWPSNSQGSPIPTQAPMPSPERIV
Protein: HISTIDINE TRIAD NUCLEOTIDE-BINDING 2 (Q8GYJ9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- TATA-box-binding protein 1
- TATA-box-binding protein 2
- Pentatricopeptide repeat-containing protein At4g30825
Sequence:
MAVTSSSMLLLRNFSTVGRVAQSVRVTSRIFFSTGELIRVLPYTRSKRLICSTRAAHNEEAAAKAAASVADTGAPTIFDKIIAKEIPSDIVYEDENVLAFRDINPQAPVHVLVIPKLRDGLTSLGKAEPRHVEVLGQLLHASKIVAEKEGILDGFRVVINNGVEACQSVYHLHLHVLGGRQMKWPPG
Protein: Cruzioseptin-11 (CZS-11) (A0A193H361)
Organism: Cruziohyla calcarifer (Splendid leaf frog) (Agalychnis calcarifer)
Function: Has antimicrobial activity.
Subcellular location: Secreted {ECO:0000269|PubMed:27321580}.
Interaction partners:
Sequence:
MVKLKKSLFLVLFLGLVSLSICEEEKREEENEEVQEDDDQSEEKRGFLDIVKHVGKAAGKAALNAVTEMVNQGEQ
Protein: Transcription elongation factor SPT6 (Q9W420)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription elongation factor which binds histone H3 and enhances transcription elongation by RNA polymerase II (RNAPII). Required for the transcriptional induction of heat shock response genes and for maximal recruitment of two other elongation factors, Spt5 and Paf1, to the induced Hsp70. Plays a critical role in normal fly development throughout the lifecycle.
Subcellular location: Nucleus {ECO:0000269|PubMed:11040216, ECO:0000269|PubMed:11040217, ECO:0000269|PubMed:12490954, ECO:0000269|PubMed:12934007}. Note=Recruited to sites of active transcription where it colocalizes with the elongating form of RNA polymerase II.
Interaction partners:
- Uncharacterized protein, isoform B
- Transcription elongation factor SPT5
- FACT complex subunit spt16
- Transcription elongation factor SPT4
- FACT complex subunit Ssrp1
- Homeobox protein goosecoid
- LD24318p
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB3
- Ctr9, isoform A
Sequence:
MAEFLDSEAEESEEEEELDVNERKRLKKLKAAVSDSSEEEEDDEERLREELKDLIDDNPIEEDDGSGYDSDGVGSGKKRKKHEDDDLDDRLEDDDYDLIEENLGVKVERRKRFKRLRRIHDNESDGEEQHVDEGLVREQIAEQLFDENDESIGHRSERSHREADDYDDVDTESDADDFIVDDNGRPIAEKKKKRRPIFTDASLQEGQDIFGVDFDYDDFSKYEEDDYEDDSEGDEYDEDLGVGDDTRVKKKKALKKKVVKKTIFDIYEPSELKRGHFTDMDNEIRKTDIPERMQLREVPVTPVPEGSDELDLEAEWIYKYAFCKHTVSEQEKPESREKMRKPPTTVNKIKQTLEFIRNQQLEVPFIAFYRKEYVKPELNIDDLWKVYYYDGIWCQLNERKRKLKVLFEKMRQFQLDTLCADTDQPVPDDVRLILDSDFERLADVQSMEELKDVHMYFLLNYSHELPRMQAEQRRKAIQERREAKARRQAAAAENGDDAAEAIVVPEPEDDDDPELIDYQLKQASNSSPYAVFRKAGICGFAKHFGLTPEQYAENLRDNYQRNEITQESIGPTELAKQYLSPRFMTTDEVIHAAKYVVARQLAQEPLLRKTMREVYFDRARINIRPTKNGMVLIDENSPVYSMKYVAKKPVSDLFGDQFIKLMMAEEEKLLEITFLEEFEGNACANGTPGDYVEESKALYQLDQFAKHVQEWNKLRAECVQLALQKWVIPDLIKELRSTLHEEAQQFVLRSCTGKLYKWLKVAPYKPQLPPDFGYEEWSTLRGIRVLGLAYDPDHSVAAFCAVTTVEGDISDYLRLPNILKRKNSYNLEEKAQKLADLRKLSDFIKMKKPHIVVIGAESRDAQNIQADIKEILHELETSEQFPPIEVEIIDNELAKIYANSKKGESDFKEYPPLLKQAASLARKMQDPLVEYSQLCDADDEILCLRYHPLQERVPREQLLEQLSLQFINRTSEVGLDINLMVQNSRTINLLQYICGLGPRKGQALLKLLKQSNQRLENRTQLVTVCHLGPRVFINCSGFIKIDTSSLGDSTEAYVEVLDGSRVHPETYEWARKMAIDAMEYDDEETNPAGALEEILESPERLKDLDLDAFAVELERQGFGSKSITLYDIRNELSCLYKDYRTPYTKPSAEELFDMLTKETPDSFYVGKCVTAMVTGFTYRRPQGDQLDSANPVRLDSNESWQCPFCHKDDFPELSEVWNHFDANACPGQPSGVRVRLENGLPGFIHIKNLSDRQVRNPEERVRVSQMIHVRIIKIDIDRFSVECSSRTADLKDVNNEWRPRRDNYYDYVTEEQDNRKVSDAKARALKRKIYARRVIAHPSFFNKSYAEVVAMLAEADQGEVALRPSSKSKDHLTATWKVADDIFQHIDVREEGKENDFSLGRSLWIGTEEFEDLDEIIARHIMPMALAARELIQYKYYKPNMVTGDENERDVMEKLLREEKANDPKKIHYFFTASRAMPGKFLLSYLPKTKVRHEYVTVMPEGYRFRGQIFDTVNSLLRWFKEHWLDPTATPASASASNLTPLHLMRPPPTISSSSQTSLGPQAPYSVTGSVTGGTPRSGISSAVGGGGSSAYSITQSITGYGTSGSSAPGAGVSSSHYGSSSTPSFGAINTPYTPSGQTPFMTPYTPHASQTPRYGHNVPSPSSQSSSSQRHHYGSSSGTGSTPRYHDMGGGGGGGVGGGGGSNAYSMQPHHQQRAKENLDWQLANDAWARRRPQQHQSHQSYHAQQQHHHSQQQPHMGMSMNMGITMSLGRGTGGGGGGGYGSTPVNDYSTGGGHNRGMSSKASVRSTPRTNASPHSMNLGDATPLYDEN
Protein: Thiosulfate-binding protein (Q9I3L9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Binds thiosulfate specifically and with high affinity. Has no detectable affinity for sulfate.
Subcellular location: Periplasm {ECO:0000305}.
Interaction partners:
- Sulfate/thiosulfate import ATP-binding protein CysA
- Sulfate transport system permease protein CysW
- Bifunctional enzyme CysN/CysC
- Sulfate transport system permease protein CysT
- Sulfate adenylyltransferase subunit 2
- Sulfate-binding protein
- Adenosine 5'-phosphosulfate reductase
- Sulfite reductase
- Gamma-aminobutyric acid-binding protein
- FMN reductase
Sequence:
MKRLFSASLLAAGLALGGAAHAAQPLLNVSYDVMRDFYKEYNPAFQKYWKAEKGENITIQMSHGGSSKQARSVIDGLPADVITMNQATDIDALADNGGLVPKDWATRLPNNSAPFTSATVFIVRKGNPKALKDWPDLLKDGVQVVVPNPKTSGNGRYTYLSAWGYVLKNGGDENKAKEFVGKLFKQVPVLDTGGRAATTTFMQNQIGDVLVTFENEAEMIAREFGRGGFEVVYPSVSAEAEPPVAVVDKVVEKKGSRAQAEAYLKYLWSDEGQTIAANNYLRPRNPEILAKFADRFPKVDFFSVEKTFGDWRSVQKTHFIDGGVFDQIYSPN
Protein: Protein TEX1 (Trex component 1) (P53851)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component the TREX complex, which operates in coupling transcription elongation to mRNA export.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- THO complex subunit 2
- THO complex subunit THP2
- THO complex subunit HPR1
- THO complex subunit MFT1
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22
- ATP-dependent RNA helicase SUB2
- RNA annealing protein YRA1
- Serine/arginine
Sequence:
MSTIGAVDILNQKTITSEVAASVTSKYLQSTFSKGNTSHIEDKRFIHVSSRSHSRFTSTPITPNEILSLKFHVSGSSMAYSRMDGSLTVWFIKDASFDKSVEVYIPDCCGSDKLATDLSWNPTSLNQIAVVSNSSEISLLLINEKSLTASKLRTLSLGSKTKVNTCLYDPLGNWLLAATKSEKIYLFDVKKDHSSVCSLNISDISQEDNDVVYSLAWSNGGSHIFIGFKSGYLAILKAKHGILEVCTKIKAHTGPITEIKMDPWGRNFITGSIDGNCYVWNMKSLCCELIINDLNSAVTTLDVCHLGKILGICTEDEMVYFYDLNSGNLLHSKSLANYKTDPVLKFYPDKSWYIMSGKNDTLSNHFVKNEKNLITYWKDMFDNTMIEKRRKNNGGGNNHNKRTSKNTDRIGKDRPSRFNSKK
Protein: PDXDC1 protein (Pyridoxal dependent decarboxylase domain containing 1) (Q86XE2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAGWSHCGTTTRYDCVRSRLTTRLPGSTGEQAPP
Protein: Gap junction protein (A0A024RDS4)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, gap junction {ECO:0000256|ARBA:ARBA00004610}. Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}.
Interaction partners:
Sequence:
MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESKQNEMNELISDSGQNAITGFPS
Protein: Nif-specific regulatory protein (P30667)
Organism: Azospirillum brasilense
Function: Required for activation of most nif operons, which are directly involved in nitrogen fixation.
Interaction partners:
Sequence:
MPGAMRQSTSNLELLTIYEVSKILGSSLDLQQTLREVLRALAYQLQMHRGRVYLVGEDNVLRLVAANGLSNEAAAQIEFRDGEGITGRILKTGMPAVVPNLAEEPLFLNRTGGREDLDEQVASLVGVPIKAAGVVVGVLTIDRISDEGPQGHFGSDVRFLTMVANLIGQTVRLHRTVAEERRFMMRETFRMQKELRPVAAPINDVVCTSPNMLEVMAQVHRVAPFKSTVLIRGESGTGKELIARAIHNMSPRKDAPFIRVNCAALPESLLESELFGHEKGAFTGAQKDHKGRFELASGGTLFLDEIGDISPNFQAKLLRVLQEQEFERVGGSKTIKTDVRLICATNLNLEEAVGHGKFRADLYFRINVVTIHLPPLRERRQDIGPLARHFVAKFAKDNGMALVMEDEALEVLNRCTWPGNVRELENCIERAATQSRDGIIRTESLSCSLNLCNSSVLFQYRTLGASVGGLAPSMGPGAINRVPPGRPGGPAAANAPKTPAMPAPVPEPAGAAAARGRPARRVVPRPLAGLRRRPAGGSGPPDPACPCPSRAPLPPQAPPPSPAAAPPPAAEVPLDEPESGSLRDRLLWAMERTGWVQAKAARLLGMTTRQVSYALRKYNIEIKRF
Protein: Sushi-repeat-containing protein, X-linked (A0A8I6ANX7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MPRGSRWGTGGLGQYLRPNRVAPAVFPKQAQIPFAAFGMAEPESLVPDTGAVFTFGKTKFAENIPSKFWFKNDVPICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIGFFTPSDIIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLKNKSNVCIPHEVTVGKPISWISCGYYHSAFVTTDGELYTFGEPENGKLGLPNQLLINHRSPQRVLGIPDKVIQVACGGGHTVVLTEKVVYAFGLGQFGQLGLGTFLFETSEPKIIDRIKDQKISHISCGENHTALMTDIGLMYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLKFTVQLIACGGCHMLVFATPRLGTIDETEFEEVYEPYMSTGSLSINDLSPGSSLNRSLSARLRRRERERPSCSASMVGTLPPLEGTSASTSASYFSPSSIPFRLSVNNYPEKSTSDSTEPLDSDYFEDKMNKETETENSSAVDLENFGETIDILNMTHMMTTSSNEKSLDFSPIQKQQIPQLSESVKPEAEGMDEQISVPNVEDTVEEEGKKEKETVEEGSLPEDALPETEGSETVVPADEKPAEMVKEENSASLLQRNLREYNENPKGHMYDRVKSSSSEILGGNEPTSKDIKKAKKWI
Protein: Sporulation-specific protein 2 (C6Y4C2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. Assists in the localization of spo13 to the outer surface of the SPB.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:18367542}.
Interaction partners:
- Sporulation-specific protein 13
- Sporulation-specific protein 15
- Sporulation-specific protein 3
- GTP-binding protein ypt2
- Sec14 cytosolic factor
- Membrane glycoprotein spo14
- Rab guanine nucleotide exchange factor sec2
- Serine/threonine-protein kinase ppk35
Sequence:
MSITMSDSSAYGEELMRERFEHLLKAYEKMALMVAEQEEFNAKIEDMALKLLSEKYDNEAYQAELFYRLSNCVEKVLHNKISITDLKTEYEEILEQTLKKECKAYERSCIENVKLKKRTEQATAYYASSSSEP
Protein: Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38) (O54957)
Organism: Mus musculus (Mouse)
Function: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Subcellular location: Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts.
Interaction partners:
- Tyrosine-protein kinase ZAP-70
- Growth factor receptor-bound protein 2
- Lymphocyte cytosolic protein 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- GRB2-related adaptor protein 2
- Tyrosine-protein kinase SYK
- Proto-oncogene tyrosine-protein kinase LCK
- Proto-oncogene vav
- Protein THEMIS
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Sequence:
MEADALSPVGLGLLLLPFLVTLLAALCVRCRELPVSYDSTSTESLYPRSILIKPPQITVPRTPAVSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSQQNSDDANSVASYENQEPACKNVDADEDEDDYPNGYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSVESCEDYVNVPESEESAEASLDGSREYVNVSPEQQPVTRAELASVNSQEVEDEGEEEGVDGEEAPDYENLQELN
Protein: Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase family member 4) (Protein LYS2 homolog) (Q80WC9)
Organism: Mus musculus (Mouse)
Function: Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an as yet unknown acceptor via an amide bond. May be required for a post-translational protein modification or for post-transcriptional modification of an RNA.
Interaction partners:
- Partner and localizer of BRCA2
- Acyl carrier protein, mitochondrial
- Fatty acid synthase
- Diacylglycerol O-acyltransferase 2
- Protein-cysteine N-palmitoyltransferase HHAT
- Coiled-coil domain-containing protein 13
- Protein-cysteine N-palmitoyltransferase HHAT-like protein
- Long-chain-fatty-acid--CoA ligase 4
- Long-chain fatty acid transport protein 1
- Fatty acid CoA ligase Acsl3
Sequence:
MTLQELVLRTASVYMDRTAVCFDEGNNQPPVCYSYKALLSAASELSHFLIAHCDFGGIREIGLYCQPGINLPSWILGILQVPAAYAPIDPDSPPSLSTYFMKKCDLKYVLVEKQQLSKFKSSHETVLNYDTVSVEHKDLALFRLHWEDGRVSTVLGDRADQHKVTDREDRVSAESRTPEKEHMDMRHDGCLAYVLHTSGTTGTPKIVRVPHACILPNIQHFRSLFDITQEDILFLASPLTFDPSVVEIFVSLSSGACLLIVPTSVKVLPSKLADILFSRHRVTVLQATPTLLRRFGSELIKSTVLSAHTSLRVLALGGEAFPSLTILKSWRGKGNRTQIFNIYGITEVSSWATFYRIPEEILNSAVKHESPVQLGSPLLGTVIEVRDQNGSPVLEGTGQVFLGGKNRVCFLDDEMTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIALVQQVAEELRQVESCAVTWYNQERLILFIVSKVDLVKDCIFKELQKHLPAHALPDDMVLIDTLPFTCHGKVDVSELNKIYLDYISSQPRNELHGKEELWGKLQYLWKSILCLPEDPEDTLKVPANSVFLDSGGDSLKSMRLLSEIERLTGTAIPGLLEVILSSSLLDVYNHIVQAVFTPEDRKANRSYTTKRKFSDADPEEASGKPARLESAWPSNHAGETNSVIALSRGSQVLSLGAGRLLTQLGLCLPVCSLDLIPQTNTQILKSLSPPAPDENLEKPPLFQQGSPVVGAMAMALRERWRSDTGKCVDASPLLVRAAVQDKPSTTVYIGSHSHTVKAVDLSSGETRWEQLLGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWTFTTEDAVKSSPAVDPTTGLIYVGSHDQHAYALDIYEKKCVWKLNCEGALFSSPCVSLSPHHLYCATLGGLLLALNPASGSTVWKRSCGKPLFSSPRCYQQYICIGCVDGSLLCFTHSGEQVWRFAAGGPIFSSPCVSAAEQEIFFGSHDCFIYCCSKEGHLRWKFETTARVYATPFAFSNHPRSDDALLAAASTDGKLWVLESRSGELRSVYELPGEVFSSPVVWESMLVIGCRNNYIYCLDLLCGDKNNQV
Protein: UBAP1-MVB12-associated (UMA)-domain containing protein 1 (RPA3 antisense RNA 1) (RPA3 opposite strand) (C9J7I0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFHFFRKPPESKKPSVPETEADGFVLLGDTTDEQRMTARGKTSDIEANQPLETNKENSSSVTVSDPEMENKAGQTLENSSLMAELLSDVPFTLAPHVLAVQGTITDLPDHLLSYDGSENLSRFWYDFTLENSVLCDS
Protein: Protein SSUH2 homolog (Protein ssu-2 homolog) (Q08C76)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in odontogenesis.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9Y2M2}. Nucleus {ECO:0000250|UniProtKB:Q9Y2M2}.
Interaction partners:
- Signal peptidase complex catalytic subunit SEC11.
- Reticulon 4 receptor-like 2 a.
- Dynein light chain Tctex-type 5
- Reticulon 4 receptor-like 2b.
Sequence:
MSASPAANTFGASAPPANMFDTVPGYEGTLAGGGGGYLPPPMPSVPMPVPEQAPHPPDWHIPSISEERAREAFATYVSSNCCYSSGPVTDGVITNMQSFNTYRYRLETFTESRSTEWSQEPYSGQPVDAGVQPAPGPWQIAAQPPPFFQDQKQAIKVPFTSSIKNCHVCLGMGNKPCTTCAGAGNKVCWVCNGSGSRLNDERCSHCNGQGRENCSSCSGNGSSQCDTCHGKRQLIVFINLNVKWSTEKEDFVAQDLSGLKVEKLEKVSGKELFKDSQFMVYPVMGFPDASVAQASQRIVRDHQTKFAQTSRILQQRQTIELIPVTKVNYTWKGNPYVYYVYGNEFEVNAEDYPATCCCSVM
Protein: T-box transcription factor TBX4 (T-box protein 4) (P70325)
Organism: Mus musculus (Mouse)
Function: Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Pituitary homeobox 1
- Fibroblast growth factor 10
- PDZ and LIM domain protein 7
Sequence:
MLQDKGLSESEEAFRAPGPALGEASNTSTTNAPEPALATPGLSGAALSSPPGQGADVAAAAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLVSSQLSAKPDVSPLHSAHQALQHYQYENGAHMQFAAAEPQDLPLNTFPTQRDSSLFYHCLKRRDSARHLDLPCKRSYLETPSSVGDDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSSSGPEIAGVSAVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPAHFTATTVMPRLPTIAAQSAQPPGNAHFSVYNQLSQSQVRERGPSASFPRERGLPGMCERKPPSPHLNTANEFLYSQSFSLTRESSLQYHSGMGTVENWTDG
Protein: Photosystem II reaction center protein I (PSII-I) (PSII 4.8 kDa protein) (P0C406)
Organism: Oryza sativa subsp. indica (Rice)
Function: One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01316}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01316}.
Interaction partners:
- Photosystem II reaction center protein J
- Photosystem II reaction center protein T
- Photosystem II reaction center protein L
- Photosystem II CP47 reaction center protein
- Cytochrome b559 subunit beta
- Photosystem II reaction center protein H
- Cytochrome b559 subunit alpha
- Photosystem II reaction center protein K
- Photosystem II reaction center protein Z
- Photosystem II reaction center protein M
Sequence:
MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGRDE
Protein: Uncharacterized membrane protein C6F6.13c (Q9US10)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MAEQKIISLFDDDACTRYTILIASTIGEMREKKESIIDNTDPEIVKYLSQLLDVFRENFDTWAMAVVNRTGCALDPSTPKDQVEVKKFRQFSETEKSECFIKCLLLLILSLGNYSPYSRNLLYSIAEKLGLSSIVVYKAELITSSMLLDTFQTMESNQEMYELSGTRKMRRRIAMGLAGLAGGALIGLTGGLAAPFVAAGLGTLFAGLGLGTMIGATYLGTLITSAPMITALFGGFGAKMSMQQMGDVSKGLTDFEFIPLSVQSHLPVTIGISGWLGDYNEVDAAWKSLTVGDKSYYWGDIYALKFEVEALVDLGKSLSRILFSAGLGWVKGEVISRTILAPLAAALWPLSLLKVGNILGNSWRIAFNLSIKAGEALANALCVRAQGMRPVTLIGFSLGARTILECLLHLADRGETNLVENVIVMGAPMPTDAKLWLKMRCVVAGRFVNVYSASDYVLQLVYRVNSAQSTAAGLGPVSLDSNTLENVDVGDLVEGHLQYRWLVAKILKERLGYDNISDAEIQSLAVQEEKYESKQRTYYSQKEQEEEIEQEVLFDASSDTELAIQKKEDEVNEVRENKK
Protein: Keratin 78 (E9Q0F0)
Organism: Mus musculus (Mouse)
Interaction partners:
- Cysteine-rich tail protein 1
Sequence:
MSLSPCRAQRGFSAHSACSAFSGARGRTGFSSRSLSSSRRCRGSSCGRAWGAETRQGIRFGQGKGGPGFSQCPPGGIQAVTVDQSLLTPLKIEVDPQFQVVKTQETREIRSLNNQFASFIDKVRFLEQQNKVLETKWELLQQLQGNRSPQGLECIFETCLARLRQQLEELQRERRALDSELKTYQDQEDEYKSKYDQEAYKHASVQNDFVVLKKDVDEVFQSKMDLEGNLESLKEHVCFLTRLYEEELGQLKTQADDMSVVLSMDNNRCLDFSDIIAEVRARYEEITRTSKAEAEAVFQTKYQELQESAQLQGNSMKEAQVQISQLRQAIHRLQSQIGSLRKQNDSLQSAIADAEQQGEMAVRDAQAKLDELEAALRTAKQDMAQMLRDYQELMGTKLSLDVEIAMYRRLLESEECRISTEHTSQVTVSITEGSIVPGRTCGGQVVVPGRIGTGQVVMPGRECGGHVVMPGRGSGGQVTIPGRGSGGQVTVPRGECGGQVTMPGRGSGGQVTMPGRGSGGQVTIPGRGSGGQVTVPGRGSGGQVTIPGRGSGGQVTIPGRGSGGQVTVPGRGSGGQVTIPGRGSGGQVTIPGRESGGQVTIPGRESGGQVTMPGREYGGQVTIPGRESGGQVTMPGRGSGGQVTMPGRGSGGQVTVPGREYGGQVTVPGRGSGGQVTVPGREYGGQVTVPRGECGGQVTVPGREYGGQVTMPRGECGGQVTMPGREYGGQVTMPGRESGGQVTVPGREYGGQVTMPRGECGGQVTVPGREYGGQVTMPRGECGGQVTMPGREYGGQVTVPRRECGGQVTVPGREYGGQVTMPGRESGGQVTVPGREYGGQVTVPRGECGGQVTVPGREYGGQVTVPRGECGGQVTVPGREYGGQVTMPRGECGGQVTVPRGECGGQVTMPGREYGGQVTVPGREYGGQMTMPGRECGGQEVIPRGECGGQVVMPGQECGGQAVIPRGDCGSQVVIPREECGGQVSMPRGECGGQVGTCGHRGWQGSFGSGGCSSIVTGGFEIPQGSGYSPTMGSCSVSGSGFSSGSGSSCRTILKKTVESSRKMSVIY