wanglab/gogpt-training-data huggingface dataset:
Protein: General transcription factor IIF subunit 1 (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Q3THK3)
Organism: Mus musculus (Mouse)
Function: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- General transcription factor IIF subunit 2
- Transcription initiation factor IIB
- General transcription factor IIE subunit 1
- DNA-directed RNA polymerase II subunit RPB2
- RNA polymerase II subunit A C-terminal domain phosphatase
- DNA-directed RNA polymerase II subunit RPB9
- General transcription factor IIE subunit 2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB7
- General transcription factor IIH subunit 4
Sequence:
MAALGSSSQNVTEYVVRVPKNTAKRYNIMAFNAADKVNFATWNQARLERDLSNKKIYQEEEMPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTAYYIFTQCADGAFEAFPVQNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRSRKKPSELRIHDLEDDLEMSSDASDASGEEGSRTSKAKKKAPVTKAGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSPDETEGKPKVPQQEDGPKGVDEQSESSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSDDSDSSEESDIDSETSSALFMAKKKTPPKRERKPSGGSSKGTSRPGTPSAEAASTSSTLRAAASKLEQGKRTSETPAAKRLRMDTGPQSLSGKSTPSSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMIGDKMHFSLKE
Protein: Collagen alpha-6(VI) chain (A6NMZ7)
Organism: Homo sapiens (Human)
Function: Collagen VI acts as a cell-binding protein.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Deposed in the extracellular matrix of skeletal muscle. {ECO:0000250}.
Interaction partners:
- Platelet glycoprotein VI
- CD44 antigen
- Integrin alpha-9
- Integrin alpha-8
- Prolyl 4-hydroxylase subunit alpha-3
- Integrin alpha-6
- Integrin alpha-7
- Collagen alpha-2
- Integrin beta-8
- Integrin alpha-5
Sequence:
MMLLILFLVIICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSENILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVKSFINSIRRAINKYPPINLKIKCNRLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFFQDKKYLSRVARSGRDDAIQNFMRSTSHTFKNGRMIESAPKQHD
Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) (Q91086)
Organism: Meleagris gallopavo (Wild turkey)
Interaction partners:
Sequence:
MSMLTPVLQPPEVKEYLSRGERFIKWDDETASASPVILRVDPKGFYLYWTYQNKEMEILDITSIRDTRVGRFAKIPKCQKLREVFNLDYPHSTFLLKTLTIVSGPDMVDLTFHNFVSYKENVGKSWAEDIMAIVQNPLTYNASRYTFLEKILVKLKMQLNAEGKIPVRNIFQMFPADRKRVEAALNACHLPKGKNDAINPEDFPETVYKTFLMNLCPRPEIDEIFTSHHFKAKPYMTKEHLAKFINKKQRDSRLNDILFPPAKPEQVQSLIEKYEPSVINIQRGQLSPEGMVWFLCGPENNVIALDKLVLYQDMTQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDCWKGRPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSLYPVILSFENHVDSPKQQAKMAEYCRTIFGDMLLTEPLEKYPLKPGVPLPSPKDLLGKILIKNKKKQFVSEKRQSSMKKGKNVEPEIIEQPAFTDAEDTVWAGDVAEEEPEEEDDQLGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPIKFDSFEVSAQKNRSYVISSFTELKAYDLLTKFPMQFVEYNKRQMSRIYPKGTRMDSSNYMPQMFWNVGCQMVALNFQTMDVPMQQNMALFEFNGQCGYLLKHEFMRRPDKQFDPFSVDRIDVVVASTVSVTILSGQFLSDRSVKTYVEVELFGLPRDTKRKYRTKLTSTANSINPVWKEEPFVFEKIVMPELASLKIVAFEEGGKFIGHRVIPIIAVHSGYHHVCLRSESNMPLTMPSLFVYLEVKDYVPDAWADLTIALSNPIKFFNLQEKRSVNLKDGSEVERPDMQRNFSFPENNGIPESTRIFSTPFANGPAGAAALVKDGNMKEVTQLPEPQTASLAELQQMKLFLKLLKKQEKELKELERKGSKRREELLQKYSVLFLEPVYPRGKKRSMHSRKTQKKRSLTTGDVGTCMQPVEMAEKLDSQVVELKERLEMELIHLGEEYHDGIRRRKEQHATEQTAKITELAREKQIAELKALKESSESNIKDIKKKLEAKRLDRIQVMMRSTSDKAAQERLKKEINNSHIQEVVQTIKLLTEKTARYQQKLEEKQAENLRAIQEKEGQLQQEAVAEYEEKLKTLTVEVQEMVKNYMKEVFPDGPEIQKEAVLSIPVEEQGSTKQLEEKIPGAEVPRLTAATTEPPGAETDINIEESIL
Protein: Borealin (Cell division cycle-associated protein 8) (MESrg) (Q8BHX3)
Organism: Mus musculus (Mouse)
Function: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q53HL2}. Cytoplasm {ECO:0000250|UniProtKB:Q53HL2}. Chromosome, centromere {ECO:0000250|UniProtKB:Q53HL2}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q53HL2}. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with SENP3 in the nucleolus in interphase cells. {ECO:0000250|UniProtKB:Q53HL2}.
Interaction partners:
- Inner centromere protein
- Aurora kinase B
- Baculoviral IAP repeat-containing protein 5
- Cell division cycle protein 20 homolog
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Shugoshin 1
- G2/mitotic-specific cyclin-B1
- Cyclin-dependent kinase 1
- ATP synthase F
- Aurora kinase A
Sequence:
MAPKKRSSRGTRTNTLRSRKLASFLKDFDREVQVRTKQIESDRQTLLKEVENLYNIEILRLPKALQGMKWLDYFALGGNKQALEEAAKADRDITEINNLTAEAIQTPLKSVKKRKVIEVEESIKEEEEEEEEGGGGGGRTKKSHKNLRSAKVKRCLPSKKRTQSIQGRGRSKRLSHDFVTPAMSRLEPSLVKPTPGMTPRFDSRVFKTPGLRTPAAKEQVYNISINGSPLADSKEISLSVPIGGGASLRLLASDLQRIDIAQLNPEALGNIRKLSSRLAQICSSIRTGR
Protein: Crk-associated substrate (P130CAS, isoform G) (Q7KVE5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MLDKTTSSSVSVSTSCCSSNAINADLDYDVPVSRRILIKSKLYAKAIYDNYADTSDELPFKKGDILTVLEQDTEGFQGWWLCSLRNRQGLCPGNRLRVLNSYDSGCFSPSPASSPVPSLAASTATLDSSICSAEIYENGSVISAVSSSNSNSGGASSGLGSESVSRVSRRSWHASPTKVITPQRHGDVYIYNYSPGSATGSGARAAPSTPQQQIYSNQSIYQNFAMMSSPRQNASGSEFETYDIPKPATPVPLNYDSPRSGLPKASNSTTTSSSSLGTRFETLKSVAASIAEESYDVPRPLILGSNQLQQQMSQMTPSSSASSLLTSDSLSLSFSSSNRSSLANMPDYDIPRRNPLPVRRQQSGLTYDFPLPPLQEQVPRVLCTPSTVTTTKELPLELSSALETLAKLQLQTTAAINRLLSFVVPNWRTRAQLEPAIMDLKLAALRLRTTLHDLAEFGEGALGNATRSEDRNLALKLRPLVRALRDANKLIHDSSESLDAQGAWSIDQLARSDEKHGCRPPDALDQLMVCAQTLTEDVRSTTSFIQGNASLLFKRQLTVGHNGGSGTGVLEGSRGSAEWLEDYDYVAFESKDAAARKNEALREAIPADLKTQFDTVIRTAESSAMGAGSGSIPTTPTARTTPTTPCKSPEMTDKDKKLVRYYAQQISTHMGNLMQAIDSFLETVEKNQPPKFFIAYGKFVVVSAHNLVTIGDNVYRNISKEALREKILRCTNALSDALKTCVLKSKKAAAHFPSGSAVQEMVDSVVHINNLARDLKSVMLQAVHLSTAAGVGA
Protein: FAS-associated factor 1 (Fas (TNFRSF6)-associated factor 1) (B0UXY9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- UBX domain-containing protein 1
- Ubiquitin recognition factor in ER-associated degradation protein 1
- Tumor necrosis factor receptor superfamily member 6
- UBX domain protein 7.
- UBX domain-containing protein 6
- FAS-associated death domain protein
- ASPSCR1 tether for SLC2A4, UBX domain-containing.
- NSFL1
- Transitional endoplasmic reticulum ATPase
- BTB
Sequence:
MASDSNMDREMILADFQACTGIDNIAEAITLLELNNWDLVAAINGVIPQENGILQSSFSSEASQTGPYGPHSQSEATAPTPSAPPPSASESASASASSSSSPPSSSSPAFCPVQPSRHIVERQSRMLSFRVEYRQRSIEVVLEDASTVGEIKTILETELQVPVSKMQLKGWKSGDVSDSTVLRSLHLPKNNSLYVLTPDIAPSASTSQSSAQQGLSNQNYLLVISHREAQRDYSLNFPASKTIQEVKRNISDLTNIPVRHQQWDGWPASATDDSMTLAISGISYPCHHLTVCRRSSPALTVDQTDECTDVHMVSDSEGDDFEDAPEFGVDESEIFGMGSSSCRKSPMMPENSENEGDALLHFTAEFSRRYGDCHPVFYIGSLEAASQEAFYGKARDRKLLAIYLHNDESVLSNVFCSQMMCADSIVSYLSQNFITWAWDVTKEANKARLLTMCTRHFGSVVAQTIRTYKTDQFPLLLIVMGKRTSNEVLNVIQGNTTVDELMMRLMGAMEIFTAQQQEDIKDEDEREAREMVKREQDEAYRVSLEADRKKREAQEREEAEQVRQERIRKEQEEEREAIRLSLEQALPPEPKEEGGEPISKLRIRTPSGEFLERRFLGTCKLQVLFDFVASKGYPSDEFKLLTTFPRRNITQLDPAWNLVEAKLFPQETLFLEAKE
Protein: Duffy receptor (Duffy receptor precursor) (Duffy-binding protein) (PvDBP) (Erythrocyte-binding protein) (P22290)
Organism: Plasmodium vivax (strain Salvador I)
Function: Binds to the human erythrocytes Duffy blood group determinant.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MKGKNRSLFVLLVLLLLHKVNNVLLERTIETLLECKNEYVKGENGYKLAKGHHCVEEDNLERWLQGTNERRSEENIKYKYGVTELKIKYAQMNGKRSSRILKESIYGAHNFGGNSYMEGKDGGDKTGEEKDGEHKTDSKTDNGKGANNLVMLDYETSSNGQPAGTLDNVLEFVTGHEGNSRKNSSNGGNPYDIDHKKTISSAIINHAFLQNTVMKNCNYKRKRRERDWDCNTKKDVCIPDRRYQLCMKELTNLVNNTDTNFHRDITFRKLYLKRKLIYDAAVEGDLLLKLNNYRYNKDFCKDIRWSLGDFGDIIMGTDMEGIGYSKVVENNLRSIFGTDEKAQQRRKQWWNESKAQIWTAMMYSVKKRLKGNFIWICKLNVAVNIEPQIYRWIREWGRDYVSELPTEVQKLKEKCDGKINYTDKKVCKVPPCQNACKSYDQWITRKKNQWDVLSNKFISVKNAEKVQTAGIVTPYDILKQELDEFNEVAFENEINKRDGAYIELCVCSVEEAKKNTQEVVTNVDNAAKSQATNSNPISQPVDSSKAEKVPGDSTHGNVNSGQDSSTTGKAVTGDGQNGNQTPAESDVQRSDIAESVSAKNVDPQKSVSKRSDDTASVTGIAEAGKENLGASNSRPSESTVEANSPGDDTVNSASIPVVSGENPLVTPYNGLRHSKDNSDSDGPAESMANPDSNSKGETGKGQDNDMAKATKDSSNSSDGTSSATGDTTDAVDREINKGVPEDRDKTVGSKDGGGEDNSANKDAATVVGEDRIRENSAGGSTNDRSKNDTEKNGASTPDSKQSEDATALSKTESLESTESGDRTTNDTTNSLENKNGGKEKDLQKHDFKSNDTPNEEPNSDQTTDAEGHDRDSIKNDKAERRKHMNKDTFTKNTNSHHLNSNNNLSNGKLDIKEYKYRDVKATREDIILMSSVRKCNNNISLEYCNSVEDKISSNTCSREKSKNLCCSISDFCLNYFDVYSYEYLSCMKKEFEDPSYKCFTKGGFKDKTYFAAAGALLILLLLIASRKMIKNDSEEATFNEFEEYCDNIHRIPLMPNNIEHMQPSTPLDYS
Protein: ADAM metallopeptidase with thrombospondin type 1 motif 9 (E9PYV8)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Beta-1,3-glucosyltransferase
Sequence:
MEGPAIDGSWGGWSHFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCMKQKRDFREEQCAHFDGKHFNINGLLPSVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDICVQGLCRQAGCDHILNSKARKDKCGICGGDNSSCKTVAGTFNTVHYGYNTVVRIPAGATSIDVRQHSFSGKSEDDNYLALSNSKGEFLLNGDFVVSMSKREVRVGSAVIEYSGSDNVVERLNCTDRIEEELLLQVLSVGKLYNPDVRYSFNIPIEDKPQQFYWNSHGPWQACSKPCQGERRRKLVCTRESDQLTVSDQRCDRLPQPGPVTEACGTDCDLRWHVASKSECSAQCGLGYRTLDIHCAKYSRMDGKTEKVDDSFCSSQPRPSNQEKCSGECSTGGWRYSAWTECSRSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVVVQSCNEFSCPHWKTGDWSECLVTCGKGHKHRQVWCQFGEDRLSDRMCDPEAKPEPMQTCQQPECAAWQAGPWGQCSVTCGQGYQLRAVKCIMGTYMSVVDDNDCNAATRPTDTQDCELASCHPSILALEPRRNAQSIPRTQWRFGSWTPCSATCGKGTRMRYVSCRDEDGSVADESACATLPKPVAKEECSVTPCGQWKALDWSSCSVTCGQGKATRQVVCVNYSDHVIDRSECDPDYIPETDQDCSMSPCPQWTGLAHPFQNEDFRPRSDSPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTANDCVERIKPDEQRACESGPCPQWAYGSWGECTKLCGGGMRTRLVVCQRANGDRFPDLSCEVLDKPTDREQCNTHACPQDAAWSTGPWSSCSVSCGRGHKHRNVYCLAKDGSHLESDNCKHLPKPHGHRRCRGGRCPRWKAGAWSQCSVSCGQGVQQRHVGCQIGTHKAARESECSSYSRPESERVCQASPCPLYTWRAEQWQQCTKTCGEGSRYRQVVCVAEDQSEVHSTHCDSDQRPPDRESCSLQPCEYVWITGEWSECSVTCGKGYRQRLVSCSEIYTGKENYEYSYQTTVNCPGAQPPSVHPCYLRDCPVSATWRVGNWGSCSVSCGIGVMHRSVQCLTNEDQPSHLCPTDTKPEERKACRNVYNCELPQNCKEVKKLNSASVDGEYFLAVRGKPLKVFCAGMNSDYPKEYVTLAHGDSENFSEVYGHRLHNPTECPYNGSRRDDCHCRKDYTAAGFSSFQKIRLDLTSMQIITTDLEFARTSEGHPVPFATAGDCYSAAKCPQGRFSINLYGTGLSLTESARWTSQGNYAVSDIKKSPDGTRVVGKCGGYCGKCTPSSGTGLEVRVS
Protein: M-spondin, isoform A (M-spondin, isoform B) (RE52725p) (Q7JY80)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- Nuclear protein MDM1
Sequence:
MGATPKTDFPAHWLLCILLALGSLSSKANAVSAYGASFISNPSIYAYSVENQPDERESRDNNIKFAAEHGNLNSNSNLNRNYYYTDDPSPVSNLNPTASLATPPATQPAPQTGCTLDRLAVYKVVLHTYWTRELFPKHYPDWRPTAQWTKTLGRTHNANYALYHIGQPATAAVKQFAESGRTDLLDSNAGEQQQVQMQLQSQMQAGKSPSGGISSGTTSFNATAASTATPTGGSGGSGGSGGSGGTGTTTAERSVFDEFSMPAIPMGAGRSEAKVFVDSNHSLVSLMTRIVPSPDWFIGVDSFELCVGGSWIDTVTVELDPLDAGTDNGFTFTAPNWPTEPQGVIYRITSRYPGHPAGSFYYPKSKRLPPIATFQFIKLKEYELSEVFNIAEDDRKYETVQTQTHLDAEHNHVEMNNELSASIERERQTEQQQLQQNDDERQRIRSQLLAKMNPIYGSNNSLQPAPGQVVSVVPKNDKHAILQSIASSYRRAADASDANASKPTPSAIGGGKAGGAVGGGAATRRRSSAQRRRDCRVSHWSEWTACSKSCGVGEMHRYRKVIKHGKRGGRQCPALQQSKWCGTERNCHGSQTYFNWSDSDT
Protein: Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (AtCBP20) (Q9XFD1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. CBP20 also plays a role in stabilization of ABH1/CBP80 and ABH1/CBP80 localization to the nucleus. Involved in flowering regulation via its interaction with FRIGIDA.
Subcellular location: Nucleus {ECO:0000269|PubMed:19453442}. Cytoplasm {ECO:0000269|PubMed:19453442}. Note=Predominantly nuclear.
Interaction partners:
- Serrate RNA effector molecule
- RNA-binding protein Y14
- Nuclear cap-binding protein subunit 1
- THO complex subunit 2
- Small nuclear ribonucleoprotein Sm D2
- Nuclear protein-like
- Regulator of nonsense transcripts 1 homolog
- Phosphorylated adapter RNA export protein
- Cell division cycle 5-like protein
- Splicing factor SF3a60 homolog
Sequence:
MASLFKEQAKLSAYRDRRFSGTQEEFDEALRASTTVYIGNVSFYTTEEQLYELFSRAGEIKKIIMGLDKNTKTPCGFCFVLFYSREDTEDAVKYISGTILDDRPIRVDFDWGFQEGRQWGRGRSGGQVRDEYRTDYDPARGGYGKLVQKELEAQRQLVDYGTGSLGAYPQAAPTNYGNGRRGGGNYGQGGQNRHGRGDYHRKRQRDDDRYGRDNSRRNTDHESRRDTDSDMRPEKNPRFRESGDSDDDGEDDRKRRS
Protein: Cyclic GMP-binding protein D (Guanine nucleotide exchange factor for rap1) (Ras guanine nucleotide exchange factor U) (RasGEF domain-containing protein U) (Q54S40)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Promotes the exchange of Ras-bound GDP by GTP (By similarity). Induces the formation of substrate-attached pseudopodia, that leads to increased adhesion and thereby negatively influencing cell speed and polarity.
Interaction partners:
- cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B
Sequence:
MTDYPFYKPDDETNIIYNININKKEGFSAIKSCSLAKLIEKLTSTKQLHTYFSSAFFLTYRDFTTPLEIINLLISRYTGPPPDSSKDSLRLFEIEVDIVQANVLSIFRTLIGTLIQVDFDTPKLSSSIIEFFNSLPESVKNELFLEFFKAKKMARPPGSIPKPVNSNIISSAASTMRFSYSVSPKTQSPNSTNNVLSGLLSNNGSNTMNGINGTSNNNVNSNNNNNNGTTNISSPNFDPSRSSMKMGKGIMKLLQSNIANFNNQQNGGGGGGSNNGTSPQSSPSSTLSSTNSLFNQQPSLSMLNDDGSVQNNNNNNNNNNNNNNVNEISTINVQLPPSTPPINGIPGEKTAFLPEAIAKELTIMEWELITALSVSDITSKEWNKSVNIQNLTTWFNRISSWVSTKIISKETPEERAIIIEAFINIANFAKELKNYNCVMEILGSLHGSSISRLKSSWALLSQKTNDMFQILNNLMTTDGNFKNYRKILTTVLPNEPCIPYLGLFLTDYTYLDESNPSLSTDSNLINIDRIFLISTRVQEFFQLFTNCNYTFISNMSVRDAILGEKVWDENEIFRLSKIREETSSLQSLKESNGIGNSNSTSGGSSSSLVNKDGSGGGGGSGGGGSVNSKGDGKGDGKDNRDGRGDGNSNCGNGSGISSKDKDLLLSSSSSAASHTVRRKNFVTKYRMSFTGNDPLPSVSSTLSEREWKILTTNSKTIIYPRGKTVLSVGETNTNIYRVISGRVKVETLKSFNSSDADLGAGGGGGGDNRGEDNSLMAIKARNRLSLNLPAQDDGYYVEEGEIFGQESFLYTDRPMLSNIIVDSGECELMEIEKSFVLQLFASEHQLSATFYKFIGVIQAQLLKSIYINFTSNYGNGGSGGSGSNGNGGGSSNGAGGGGLSSSVSIGNLNSPNINRIDFKRRSTIFETPSSLDILRDGNDSSFRTKFGLSQDEVIIKRYQCKHNNMNGTLYITKHNLCFEGKFLGINKNKTIPFDRTDKILTVDKNIMTVTTKEKVKKFTFKSHDDLNEGYGISVQIWANHLNINVKQQLQLQQQQLQQQQQQPSQQPSQQQSQSSQLQQSVSASSTTPPVPNSPKVGRGESFSNIKDLPSKDEWNQILKGTKPLTFKKGEILICEGVEYQKMFQIVKGECSVVKSLLPTPLDQNIFNNINNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNSIFKNNSSISNTNSNTSIDGGVGGGLSPQTLVDPKNSVIVSKLTHGSIFGEMSFLLPGGSATSLVVSSDEVEVYIIESYFLHILLKSKPYLASKFYKYLACVLETRVRNLT
Protein: T-cell ecto-ADP-ribosyltransferase 1 (EC 2.4.2.31) (ADP-ribosyltransferase 2a pseudogene) (ADP-ribosyltransferase C2 and C3 toxin-like 2) (ARTC2) (Mono(ADP-ribosyl)transferase 2A) (NAD(+) glycohydrolase) (EC 3.2.2.5) (T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 1) (T-cell differentiation marker Rt6 homolog 1) (T-cell mono(ADP-ribosyl)transferase 1) (P17981)
Organism: Mus musculus (Mouse)
Function: Has both ADP-ribosyltransferase activity and thiol-dependent NAD(+) glycohydrolase activity.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
Sequence:
MPSNNFKFFLTWWLTQQVTGLAVPFMLDMAPNAFDDQYEGCVEDMEKKAPQLLQEDFNMNEELKLEWEKAEIKWKEIKNCMSYPAGFHDFHGTALVAYTGNIHRSLNEATREFKINPGNFHYKAFHYYLTRALQLLSDQGCRSVYRGTNVRFRYTGKGSVRFGHFASSSLNRSVATSSPFFNGQGTLFIIKTCLGAHIKHCSYYTHEEEVLIPGYEVFHKVKTQSVERYIQISLDSPKRKKSNFNCFYSGSTQAANVSSLGSRESCVSLFLVVLLGLLVQQLTLAEP
Protein: Uncharacterized protein KIAA1958 (Q8N8K9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKAKLDCNRTRDSCDFSYCSEPSELDETVEEYEDENTLFDMVCESSVTDEDSDFEPQTQRPQSIARKRPGVVPSSLHSSSQTQMVDECSNDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKPQTHAGPSCVGSAKLIPHVTSAISTELDPHGMSASPSVISRPIVQKTARVSLASPNRGPPGTHGTNQQVAMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLSHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPVAPAITTEATAQCIPAYSTKLNKFPVFNINDDLNDLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSLSDEEEMWQAGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLKDPQNQPYFARTDSVKRESRSGSTRVCHGKIYHEHSRGHKQCPYCLLYKYMYIHRPPTQMEAKSPFYLTARKEATDMGSVWYEEQRMGLRSLRGIVPNLAKKVKLENCENFTFVSFTQVSRRLGSHSCCQ
Protein: Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Protein-lysine myristoyltransferase NMT2) (EC 2.3.1.-) (Type II N-myristoyltransferase) (O60551)
Organism: Homo sapiens (Human)
Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9506952}. Membrane {ECO:0000269|PubMed:9506952}; Peripheral membrane protein {ECO:0000269|PubMed:9506952}.
Interaction partners:
- Acyl-CoA-binding domain-containing protein 6
- Guanine nucleotide-binding protein G
- Caspase-3
- Ribose-phosphate pyrophosphokinase 2
Sequence:
MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGYLGAKKKKKKQKRKKEKPNSGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ
Protein: Opy2p (Q5A753)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Ste50p
- High osmolarity signaling protein SHO1
- Cell division control protein 42 homolog
- mitogen-activated protein kinase kinase kinase
- Mitogen-activated protein kinase HOG1
- Serine/threonine-protein kinase CST20
- Microtubule-binding protein
- Oxidative stress response two-component system protein SSK1
- Histidine protein kinase SLN1
- Extracellular signal-regulated kinase 1
Sequence:
MPIPRSFIFEPELEQLLKRDENGCVSCPSSAGSCPSCPSGQQCQLSSRTCNSCPKYYCASVSSKKGSPIGGIVGGVIGGVAFLALVGAVLYYFLIYRKKHPLILDEDFENYEDDEDFLEDETSGYASSKLTSNNGNGLDVSSPGYDSSSGNVVSPVSASNVNTTNGSSSNGPNTTVSSTSVGNTSVERAAGPGVGSGAAIVARKQIAGNSVSAAKRRQMKRLSSYESFTRPKASGNNKAKQQQLQARRARQQRIIRQANQQTQQQPQQQLPFNQYLQPSNRNSVATSFSNASNILPIAYIPGVTVRPTKNNTRSIYSYDTDSLFSDLNTIENASIIGDVVLANQNTATAEMYNPSPESSVRSENQQSQQRNYTNGPGTMTAIKAQPRLVNVDKIEEEDEDEEDSEEDYDEGRAIPEESEEDSDVDSDIGEITRATSLKRQQPGPQASNNIDGDKQIDIAPGDSTENGIPLDYINFDNGKDVGSTINSATGSFLLNVEFDHSPLTTPVKTHYTDNSNDRGSPFADPDK
Protein: Prosap, isoform C (A0A0B4LFA9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSGSGAFDDEPPPEPRDGWLLVRIHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYPFNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACRHGLVQHLEHLLFYGADMDGRNASGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAVIAGNLELAEIIENYKSEDIDKSLGDTSDIISDSSGVGTNSDSAACSIGHPSTTVVCMEPYAGNTVGHIRLQPGDVIEVVGSTDCGLLEGYVRGTNQSGFFPADCVQEVSLRQKHITNVMTASTGMAPQQQQQQHLQQAPAGSSAASYQGSPQLSLGGHSGSSSTLLQQPHQSPSLSVASNGSCQQPLESNEGGASGNGINNRNNNHSVGQYSSATAPRIKKSAYNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVSPQFPHQMQASAQYLPSGARAGSHHLNSGPSTPQSSHRQCATLPRKMTGPGGSGPGSSSGGSVRMAPMPPRRDPKTTLSVGRARAKSMVAGLENGGEKEDDLPHTKSNSVESIATPTPTGIQTGPGTPVQLRTASIKARPTSSRITAAELEELFQRQQGEGSAANASRYATMMTSSRFQSGTDSGAATPPASNGSPMRSGPLVYGSVAEMKRKTARSKHGSGTLRGKPVATPTVGPGGAGGGRDLKRFHSTPDLHGPQLHGSASSIWQASGKGHHSQDDVATLHASLQRLNSNQGELKLGGLGAGSATGAGGAVLPPPNHPPPPPPVGQVVKVETRSSVSEYESTISLQQKLKKRTENDAVTSAAIDGVQSSFNPSANAKIYASPQELRNVMAWKLRQAQEKPSQETSAGSQQPVSQYAAPTQMRPAQQQQQAQQPPTALASHYAAPQVQVQQVQQVQQSPQQSAPQSPPAPPLPQAAPVPAQNGNGNGSTSGAGSAPPIPEPDYSCSESDGEDENSILVARNTKLNEKIALFDVPETSGNSQASGSSSNSGSASISHSLSVEEIQRIRSNLKTSKSSPNGFAKKPEEEKPQQEQQQSHQQPQQLLQPGEDECDNSSSGVSSEQEQLALAAGVTLPGGGKPTDTIKKKPSVTIVEEPKTIPDQPSSNTSHTTKPMAKTTISIGGGGSAVPTATLTVKQLVQQQHAPVIQQQQQQLGSKQPVTAASTNKFTQQSNINSNVMSPQVLGRIPSHHHQQQSSNPNQKLIATQQQILQQQQQQLAHQQHLQQILKAKAAAAGGASNTAVLVAKHQQKLHKGTSSGHESEMETRSDLEDDDGDLSPSPPAKAFQRHNSLTRKQAAAIAMQRGATRTTAVSLMQLPPPLEADSDGEPSQLTLQRQQSHHPSQTHPHPHQLQQQLQLQQQQQQQQQQQQPMAAHIVGMLPSGQLVAVASGAVAGVPGVGATAVQQGNNNLQQLCTDNLVLAPPPQFCDCNDAKHAPQPHLPTSQYHPQQQQQQQHQQQQQQQQQLQQQLQQQQMLQMHQRLSGGAGAGAVGTLGRVRIVGAMPKANHHRLH
Protein: Mitogen-activated protein kinase kinase 7 (AtMKK7) (MAP kinase kinase 7) (EC 2.7.12.2) (Protein BUSHY AND DWARF 1) (Q9LPQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May function as a negative regulator of polar auxin transport. Positively regulates plant basal and systemic acquired resistance (SAR). Activates MPK3 and MPK6 in vitro.
Interaction partners:
- F12F1.31 protein
- Mitogen-activated protein kinase 6
- Peptidyl-prolyl cis-trans isomerase Pin1
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 2
Sequence:
MALVRKRRQINLRLPVPPLSVHLPWFSFASSTAPVINNGISASDVEKLHVLGRGSSGIVYKVHHKTTGEIYALKSVNGDMSPAFTRQLAREMEILRRTDSPYVVRCQGIFEKPIVGEVSILMEYMDGGNLESLRGAVTEKQLAGFSRQILKGLSYLHSLKIVHRDIKPANLLLNSRNEVKIADFGVSKIITRSLDYCNSYVGTCAYMSPERFDSAAGENSDVYAGDIWSFGVMILELFVGHFPLLPQGQRPDWATLMCVVCFGEPPRAPEGCSDEFRSFVDCCLRKESSERWTASQLLGHPFLRESL