wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein (Q38B62)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRVTCVVACGLRSSSSDLKRRRIRQLERQYGPAWRYTAGWTSQLSPVGMFDALEVPVFPPNVVQTRELDHVGCASAPRTTVVSRGLVQNGNPRVKDSQPTSVLDENNAYFNPQHDAGTSSSDDPLFEFLRHDDEHSALLLAMWTSLYRCCVHASELSEFLAFRVRWFLHHLIHMRATAAAVRFYHRLLLLGVHLQKKDVSLLLSSLPYEHYVVNVDFKGESKKKCSRFRTMRQADTTHVDKKSATNGDKGGTVVFSGDGGTVGEEERLLFASTITSTGADTSCDTSARVCPAGDTCGVESVDFELTPAGSRYLRDQPEWVKRWVLYEASMGNIDLYDEENATTLRADKYVDSSSVGLDCGDECTPSEVKWAEGCIDVVTLLNHLMLLHDGNHLIHRETRKRRVNGKGRSGITLRGEMQRHYWAEALQIAGAFLSARSSRGRERKAEEGQYEVGCSVPPEFRSELCRALVAAGSWKVALRWLKVAEQYRVGFTHSEYARIFLCLAESEPWETSRAAERFVARNMIPLLPEETVCGYASRAMWLAHVCSQRDNRVEECLELMESTSGNLPACVKQSIVYIKLAASLLRVDADRFFAAAALQQFEAASIRLGVFHPAADLSQRHSPPIQLVTRDMASAGSGALLTVQLQDSFVLVSIALPRVVELVSVAAASQEDEVQLATLLADVLYGPNGLWKFFSDVCLVGESKQLTSHRTSEVVRISLYMSLCLLKIGVALCRVVGHERQGVQGNPHLREKHLTLILGLLEESLGAIPARNAVEIKDRRIMLSLVATSAKLTKHVFRQIGVYPCNEKVIFGSFSEETSETVALMLRIHVLLWRRVSSLRRHLQLAAGSALRAVFRPTSELGKHVRGHIPRHQQQELDSMLAYGRLRKYGERRAGAAIATKSKSEARVHSPEDVARIKAVAKTHRVVYALSLQHVNNGAALERDLITYLSRASWDGALTMLHVSLHHLRLPHGTFGLPFFAGVLARLCKAPHRTKSLWFQAIGVYWDAVEHVPRPHVSANTSHVVDSKSQLRLHERNVLTQLLLPLLRFSVSTRQKEMGWSWMRRWDLMHKSDERDVEYEALSVWARSVLEDRSALKRCQRLMEKYQYQHMRQKNLPMIPPLENILCDVAVNHADWCAALHALETVFWTPQRGGDFITTPLPPRAATAVLRILCKAPTNLCNTARRLREIQGSCWDLRSANSLLLLLVRQRRWQLALQHVAEMLPVVQNGRQKSDVVGGNSVFDMCLEGDGKTEQALFLVHGLRACANGGRAEEAATLYDLVKQLAGLEAVVRAADINVESSVTYALKRPEDMLFFMCNQTDQPQDTLACDEDERMRMLVGQARVYFLRAMTKKTLRCNRR
Protein: Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6) (nm23-M6) (O88425)
Organism: Mus musculus (Mouse)
Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Interaction partners:
- Thymidylate kinase
- Bis
- Inosine triphosphate pyrophosphatase
- Nucleoside diphosphate kinase, mitochondrial
- Deoxyuridine triphosphatase.
- CTP synthase 1
- Nucleoside diphosphate kinase 3
- Nucleoside diphosphate kinase B
- Adenylate kinase 9
- Nucleoside diphosphate kinase A
Sequence:
MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRTRELQWKLEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARYIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGHKQPNKT
Protein: Probable sugar phosphate/phosphate translocator At5g11230 (Q9LFN3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MGKGGALSESVIKNIVLSYSYVAIWIFLSFTVIVYNKYILDKKMYNWPFPISLTMIHMSFCSTLAFLIIKVFKFVEPVKMTRETYLRSVVPIGALYALSLWLSNSAYIYLSVSFIQMLKALMPVAVYSIGVLFKKEGFKSDTMMNMLSISFGVAIAAYGEARFDVWGVILQLGAVAFEATRLVLIQILLGDKGIKLNPITSLYYVAPCCLAFLFIPWIYVEFPVLRDTSSFHLDYAIFGANSFCAFALNLAVFLLVGKTSALTMNVAGVVKDWLLIAFSWSVIKDTVTPINLFGYGIAFLGVAYYNHAKLQALKAKEEEKKKIQQADEESGRLLEEREGDVEGKKNDQSGN
Protein: Establishment of sister chromatid cohesion N-acetyltransferase 2 (E5RFP7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSALKTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEKMQGKPVCS
Protein: ATP binding cassette subfamily G member 1 (A0A0G2K987)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
IKCLDNPFPPGNNASNYSAAMTEPKSVCVSVDEVVSSNVDELETDLLNGHLKKVDNNFTEAQRFSSLPRRAAVNIEFKDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDYKRELGGDGDVNPFLWHRPAEEDSASMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER
Protein: IAA-leucine resistant 2 (Protein PARTITIVIRUS CP-LIKE SEQUENCE 1) (AtPCLS1) (F4J8R4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates an ATP-dependent metal transporter (e.g. manganese transporter). Probably involved in the metabolism of auxin conjugates such as indole-3-acetic acid-leucine (IAA-Leu) and IAA-Phe. Required for root development.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:12904214}.
Interaction partners:
- F-box protein SKIP17
- F-box/LRR-repeat protein At4g14103
- Plant UBX domain-containing protein 4
- IAA-amino acid hydrolase ILR1
- IAA-alanine resistance protein 1
- F-box protein At4g02760
- Transcription factor ILR3
- Capsid-like protein
- Probable calcium-binding protein CML29
Sequence:
MASESSTHKTKLEKKTCLSFLSSFTRSQIVYPTQGISHYYPSCHMMVHAMNITLCDNFDFKRANPNYHPYILRLYCGVLFWIQCLRAGNDVNDLTDVQHRFLNRFLDNHPLETLAVPGPLLGLFKTLCSSQPEFPHNHNGKVYPRIPAQPGPARRDAFMRDLLESHFLPNVPGIFALLEDLTAFLPNTSRLSKERQAHSRYPKYPDQSLNEAFADCYSNFNFQVTSAADNLEKISSFLHMKHSMAWFNQVKGVADDVAASFEGSGTLADCSPHGLVANQVMVVLSTPEHLPESPNCIADKRATYEFGYQLKSTVRNLPPLAEALAAFSQTYIRMFPNHPFFGTFGSKTLDHGPFWKIRPIGSSLTDNSSYLTIPSIVKQAFKGPAT
Protein: Phospholipase (EC 3.1.4.4) (Q9BP35)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00037868}; Lipid-anchor {ECO:0000256|ARBA:ARBA00037868}.
Interaction partners:
Sequence:
MADAGTVGGALPPYALTNSDEEHGSGEEDASEENSNNEEGEGVFRDCTDEAVVEHHNRCLPEFQFSLVDSEYDETLAFPDSVTILSNVGDKPVLVERKETDDDEEEFDDEENNSVVLRHEIPFTSIYGPSVKFNSFQRKVFIPGREIHVRIVDTERSVTTHLLNPNLYTIELTHGPFKWTIKRRYKHFNSLHQQLSFFRTSLNIPFPSRSHKEKRTTLKATAREMADESTLKDLPSHTKVKQTSTPLRAEGRSSKIAGSNANNAMAIISPNHSSILAGLTPRRIQKKRKKKKKRKLPRFPNRPESLVTVENLSVRIKQLEDYLYNLLNISLYRSHHETLNFVEVSNVSFVPGMGIKGKEGVILKRTGSTRPGQAGCNFFGCFQKNCCVRCNYFCSDVVCGTWRNRWFFVKETCFGYIRPTDGSIRAVILFDQGFDVSTGIYQTGMRKGLQVLTNNRHIVLKCWTRRKCKEWMQYLKNTANSYARDFTLPNPHMSFAPMRANTHATWYVDGAQYMSAVADGLEAALEEIYIADWWLSPEIYMKRPALDGDYWRLDKILLRKAEQGVRVFVLLYKEVEMALGINSYYSKSTLAKHENIKVMRHPDHARGGILLWAHHEKIVVIDQTYAFMGGIDLCYGRWDDHHHRLTDLGSISTSSFSGSTRRTPSLYFTKDDTDSAFGSRKSSRNAHYDTSAKERPPSPPPDEPNTSIELKTLKPGDRLLIPSTLVSSPGETPAESGIALEGMKLNTPEMERKNVLDRLKNNAMKGARMGKDFMHRLTATETEEKSAEVYTIESEEATDHEVNLNMASGGQEVAITTSSTQILSEFCGQAKYWFGKDYSNFILKDWMNLNSPFVDIIDRTTTPRMPWHDVGLCVVGTSARDVARHFIQRWNAMKLEKLRDNTRFPYLMPKSYHQVRLNPNIQQNRQQRVTCQLLRSVSAWSCGFIEADLVEQSIHDAYIQTITKAQHYVYIENQFFITMQLGMGVPGAYNNVRNQIGETLFKRIVRAHKERKPFRVYVIMPLLPGFEGDVGGSTGIAVRAITHWNYASISRGRTSILTRLQEAGIANPENYISFHSLRNHSFLNNTPITELIYVHSKLLIADDRVVICGSANINDRSMIGKRDSEIAAILMDEEFEDGRMNGKKYPSGVFAGRLRKYLFKEHLGLLESEGSSRSDLDINDPVCEKFWHGTWRRISMQNTEIYDEVFKCIPTDFVKTFASLRKYQEEPPLAKTAPDLAANRANDIQGYLVDLPLEFLNKEVLTPPGTSKEGLIPTSVWT
Protein: Elongation factor 1 alpha-like protein (EC 3.6.5.-) (O74774)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in protein translation. Together with dom34, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Protein dom34
- Translation initiation factor rli1
- Exosome complex component rrp42
- Adenylyl-sulfate kinase
- Exosome complex component csl4
- Exosome complex component rrp43
- Exosome complex component rrp4
- Exosome complex component rrp46
- Putative ATP-dependent RNA helicase C550.03c
- Exosome complex component ski6
Sequence:
MSRHRDVKNLDLDDYELDEEPGEEELTEEQEEEFRSAVATVRETLLGVPISEKEIADTVWYYYFDVEKSVNYLLQKASSKAGAKEKQNTDSQKEKKQNKSKEALADAKDPLDESSNGIKNLSLNKNDEPAFQTNGEVKMKNSSESDNQPEKKKIKKQNPTDLVSVPEIFEQSNPKPVVHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTEEERARGVTMDVASTTFESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLENGQTREHAYLLRALGISEIVVSVNKLDLMSWSEDRFQEIKNIVSDFLIKMVGFKTSNVHFVPISAISGTNLIQKDSSDLYKWYKGPTLLSALDQLVPPEKPYRKPLRLSIDDVYRSPRSVTVTGRVEAGNVQVNQVLYDVSSQEDAYVKNVIRNSDPSSTWAVAGDTVTLQLADIEVNQLRPGDILSNYENPVRRVRSFVAEIQTFDIHGPILSGSTLVLHLGRTVTSVSLKIVTVNNKRSRHIASRKRALVRISFLDGLFPLCLAEECPALGRFILRRSGDTVAAGIVKELC
Protein: Transmembrane protein adipocyte-associated 1 (Integral membrane protein GPR175) (TPRA40) (Transmembrane domain protein of 40 kDa regulated in adipocytes) (Q791F6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Transient receptor potential cation channel subfamily A member 1
Sequence:
MASLQEANGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAGVAYLDDIASMPCHTGSINSTDSERWKAINA
Protein: Adenylyl cyclase 78C (EC 4.6.1.1) (Q9VP76)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the formation of the signaling molecule cAMP in response to G-protein coupled receptor signaling. Probably downstream of gustatory receptors, involved in taste perception of sucrose, trehalose and caffeine. Has no role in bitter perception. In the circadian brain neuron evening cells (E-cells), involved in circadian pacemaker synchronization by playing a role in signaling downstream of the G protein-coupled receptor Pdfr, probably in conjunction with other, as yet unidentified, adenylate cyclases.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- RAC serine/threonine-protein kinase
- IP06402p
- Bis
- Inosine triphosphate pyrophosphatase
- LD28489p
- Molybdenum cofactor biosynthesis protein 1
- GTP cyclohydrolase 1
- 3',5'-cyclic-AMP phosphodiesterase, isoform I
- cGMP-specific 3',5'-cyclic phosphodiesterase
Sequence:
MDVELEEEEERICLRTAEEGQLANMDDDKLVSDEVHLRQLSATPSSAFSLQHSRGSDTKEEAPPEGGTMGGKSAAPREEGEPDERVVLRRAVDKGAIALAQIDDLKLEGDDDDEAVVNGEEVDGLGLSNPAAQTTDDEQITVNGTGAAATSSVAADAASSEQDAASTAMATPDMSKIPRLPGDGAQMEDNGSGDLPPSLRASTTSILSNLRKKQQGGPLRGGVAKQTPLRVQSVRIVEAKRAYGPKRRTESCSIFGNSNFEHDLESGNSLASIPGQSQRPLNNEMYSAFKSGNVVKGILCPSLTNSFKQSSLERSYLTYTHRQRQKSLIIVNVVDFVLKIVLAFVWIMRRSELGPIESDDGTSMATAITWSVCCGIANMAICFLGYWRCFANNYLHWAAVCTWVLFNIQGFVGQGVGFADREYLVWYILFVIFVPYAMLPLPLKWCVVGGTITASCHLAVITIIKLQHGEATINPECVLFQIFANFILYTAINVAGMYTKYLTDRGQRLAFIETHKAMEHKKESEKELQRTQKLLDSILPNIVNNQIRSEMYKGTDPTVETQFNKLYVYPMDNVSILFADIKGFTELASKTSAQQLVKILNDLFARFDRIAEDNHCLRVKLLGDCYYCVSQFESDNWKTRPDHAVCSVETGLHMIKAIKDVRLHTHVDLNMRIGIHSGSVMCGVLGNKKWHFDVWSNDVIIANHMESGGIPGRVHISEATLKCLNDAYEVEPGNGGCRDNHLKMLNVKTYLIKRTEPLRPKRRFGTRSSAHLAGSVATAAPPCATPTALPKSISASGSGSIGGVTATGNDGASIDGRSLEYAATIAVPAQQPTQLLQQQQKKNISLNSLPNVVEGVAMDSRRIRNGCGVMGGAGGTGGGGTGPCGMSTVSSPTAMMSAPLEVQLRPRNGACSIQNLAEAIDGKGLIIEDESTTDWIPEIPFKNLNSPEDGLNRADSILVDTKEDHRVSVAVLDEEIDEFIEQNIQINSNKEIRREYLNPWTLKFKDKSQEQKFCQLREDMFRSNMLCVFVIWIFMVLCQVIIIPRCTRLIICLSVGTVILTFCCVLVMAEEFPGLPRCLKTNSAKLVHQRQRRTLFICGVIVSMCMLSAIGLVLCPSSTYIGTADEHSRFLRMVSPYSNISMTEKEFKLNVYLSATIHHNITISTPASGGPTPLVDITSSGPSDEFVRSTLNALTLNLTPPLPQSHRPYTLTTNGHSVSLSNLSYSDASVMQSSSDVEGQCAHPEYLVFTWVLCLVSLATALKLYYLVKALMALAMVAFYTTLIMMKFGSGDSFSLVELSRLGMPLGVQMLILLISFLVMVCYHARLVEVTSRLDFIWKEQAERELTNMKSNRALNDTLIKNILPDHVATYYLSDEHTDELYSKMHNLCGVMFASIPNFQDFYSEDIDNGKACIRILNEIICDFDELLEEPRFASVEKIKTVGATYMAAAGLNHEHLRLRGETSEDSVCDLVEFAFAMKQKLEEINGDAFNNFQLRVGICSGPLVSGVIGARKPVYDIWGNTVNVASRMDSTGENWRVQVPENTAELLCSRGYTCVKRGEIAVKGKGMMTTFYVHPKGISESQLISPVRMPAGIPLAQTPNLQRQTSHHGSFSAVVFGMLQASKRSTAIAGTPTGTPSPQIRRGHRGSTFSSVRLSQKSTTVNPVRRNTTRVRGRSYRQKKSSSNNSIVTQASSSYMPSFRRIDQIETTISKSHNDAL
Protein: Integrin alpha-9 (Integrin, alpha 9) (F1Q8T4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Interaction partners:
- Integrin beta
- Vascular cell adhesion molecule 1b
- Integrin beta
- Tenascin C
- Tenascin R
- Tenascin N
- Integrin beta
- Integrin beta
- Lymphatic vessel endothelial hyaluronic receptor 1b
- Breast cancer anti-estrogen resistance protein 1
Sequence:
MPNRMTELSTRKIRALDVFVCLCSVSLAYSFNIDLQYPVVFRGPDATFFGYSVLEHVHDNTRWIVVGAPRANSSFSSSVQSPGAVYKCRIRNNPEQRCTEMDLGRGNKQRESCGKTCQGDRNDEWMGVSLARQNKPNGKILACAHRWKNVYYESEYILPHGYCSIIPANLQGKSQPLIPCYEDHKKTYGEEHGSCQAGIAGVFTEELVVMGAPGSYYWTGTVKVFNMTSNTHYNLNQDDLSPHRYSYLGYAVTAGHFSSPNTIDVAAGAPQDSGGGKVYVFRIEGTALVKIFQASGKMMGSYFGSSLCAVDLNADGLSDLLVGAPMHSEIRDEGQVSVYLSSGNGVMEEVAILNGDNAYNAHFGECITSLGDIDDDGYQDVAIGAPEEDDYGGAVYIYHGDARGIVNKYSMRLSGRSINPTLQMFGQSISGNVDMDGNGYPDVTIGAFMADSVVLLRSRPVISVDVSIFLPVSINITVPQCHEGPQHLNCFNVTVCMSFRGKHVPGHIELLYNLTADSDKRHKGLPPRAYFGNGGEQTGVVSQRFNLEIHRQQCHQYTAFVRKEVKDVFAAIVFEAAYSLGKHIVDEHQDRDLPPLSPILRWKKGEKIAAKNETWFEKNCLSDDCAADLQLHGKLLLSGRYISSHLALGGVKNVSLNLTISNAGDDAYDTNIYFNFSKEVHYINFLQREEKGISCMLVELDFLKCSVGFPFMRAQTKYHISALFDTSRLSGENETLLFLVHARSANPEHDNTLHDNTLELSIPLVHEVDTTITGVVNPTSFVYGNSVDRSRFVQLEDMECSFQPLNFTFQVINNGPSRLPGSRVDIRIPHRLAGSGPEMFHIIDTQVSDARGNCTWHRNPKPCTIPQDKESIFHTIFAFFTKSGRKVLDCDRPGRACLTISCSLGSQAKEEATSIDVQMLLNTEILQRDSSSVIQFVTRGHVQLDDRTVEVSSGLPDDISLVMEALHSQEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRHYREIIEAEKNRKDSDESWDWVQKSQ
Protein: Adenosine transporter 2 (Q586M9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAMLGFESTAEFFVYLTFIFFGMSVMNVTNAIYSVPDFFSDYYKFVKNEEKAKPVNASFWKHMFTYYNVVVFTMQVVLEAFMLTPLGRRIPISWRLIFGLTIPMGEIIAILVIPAVGGSENCAIATVMMVAFVGGISKTLCDSSNAALAGPFPTKFYGAIVWGLSVSGMITSFMAIVIKASMKDSFESKRVQSQIYFGLVMLLQVVACVLLVLLRKNPYAIKYAAEFRYAARKDGKTDDGEDENDAKGTGPADEDGYPDEKENKNVLNADIDPDKMKDTDQVEGTTNVQQMLDASVMVVVKRIWPMLLSCFFVFFATLLVFPGVFFAVKDGLNVKNGWYFTIVIAMFNFGDFLTRLLLQFKQLHLSPRMVMIGSFARALLIIPLSLCAAGTIPGIWLPYTVSLLWGLTNGYFGGLTMIYGPRTGSLTTAGQRSLAAISTNVSLLSGLFVGAMFALAVKEGLPE
Protein: Hybrid signal transduction histidine kinase K (EC 2.7.13.3) (Protein sombrero) (Q86CZ2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in a signal transduction pathway that regulates morphogenesis and controls entry into the culmination stage. May act via the regA pathway, being activated by a morphogenesis-stimulated ligand, reducing phosphodiesterase regA levels and allowing cAMP level to rise to promote the culmination stage. This protein probably undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain.
Subcellular location: Nucleus membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MIELNNHSKINKNENNTNTRNNSSNNNNNNNNINKTNTNKYFEYNQNSIIYSSIPNSFLSHHPNSVGSQCLSLNSFLPPKPPILLSIFNSDTIGNNNNNNYSSSSSRNNSSGCSSSNNNNNNNNNNNNNNNNNNNNNNNNCNIEQYKNNQKQPKQQQQQKDQTIATQHRISLSSSSSSSSLSSSSSSSSVKQSFQIVKRLFGSLSEYMFPQKDEILYETDPYYLYQDDTQSNDSNEFYDDTDIGSDIDEANLNNTYNIQNCNKTLYNKQQQQAHFVNMNKNVNSNNGTGNSNQSNNVNKNQQNNNNNNNNNSHNNNNGNQNSSSSSSNSGASGSGGNGNNNNNNNNNNNNNNNNNNNSNSNSNNNSKSNNNNKKEGKDGATMNGSHPLIPFRKKPAQVPSPCFRMNSPNSDNDQYLDQLALENSSKKSLVVYNTDNLDQWKHSHLNENFDILQNDLIDIQQQQQQQQQQDNTLQYSSPINKRQEQEQQHIPFQFTTEQQQQLQQQQQQQQQNKTKQHPILLQRQQQQKQKQQQQQQIQQEQIGNNNSNNNNNINNNNNINNNYNNVNDLMNKFEIDQKQHDSQQNLVEEKRTPSFHEHNIIFNSFNFICSIVLDGSNIKSTEKYKAKLIIGFCFTILSFIPSWIIFFWLSGINKPAVMAIIAMPMSISSLVILKRTGSIHYPCHILCFTLCFALTINSYYTGGHQSTIRLLMSTVPIISALVLGRKASIQWSLMVLSIYLLFFVANLYGHEYVQGIPSIIIRSHMNFIIDVTIIIMTLIFTLCYQYFIDEAHRETKLKNAQLTIAKDAAIEAYQARQEFLATMSHEIRTPLNGLIGMATLLRDSHNLPPEEKTMAKAVKSCGDILLRLVNDILDLSKLEANQMGLEHIPFRMRELTQQICHVLSGQANEKNIHLSCEVSDKIPSILLGDSGRILQILMNLTGNALKFTQSGYVKIIIDLIEEESELVSLKKGEYNISFRVKDTGIGVPVESHQKIFEAFVQADPSDSRKYGGSGLGLYLCAKLVRLMKGEIGVYNNPDCDGSTFWFILPLEEGTDQSMQQMNNGARHKAFPQDCVKVLIAEDNIINQRVAVKFLEKIGIKAEVAGNGNEVLEILERQHYDLIFMDFQMPILDGLRCSKTIREFEQNHKWNRICPSIFICGLTANTMSTDKKRCFDHGMNHFISKPFQLEQLRSAIEMAIEHKQRNLMNLNIRN
Protein: Heterogeneous nuclear ribonucleoprotein U (A0A1W2PP35)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
GLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
Protein: 40S ribosomal protein S25 (Q57XX0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 40S ribosomal protein S5, putative
- Ribosomal protein L37
- 60S ribosomal subunit protein L31, putative
- Large ribosomal subunit protein uL5
- Ribosomal protein
- 40S ribosomal protein S4
- 40S ribosomal protein S15a, putative
- 60S ribosomal protein L2, putative
- 60S ribosomal protein L35A, putative
- 60S ribosomal protein L7a
Sequence:
MPPKKGGKDTKQAPKKGKMENLNKGAKKAAKKWSKGRTREALQNAVMFDKETMDKLMKEVPKYKVITPSIISDRLKISVALAGKGLQHLCRQGLIRLVSCSSKFRVYTRAATA
Protein: RE41968p (Q8SXZ3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKTESNEKWVVCRVCLNNPSEGEELLNDIFSETASTRLDQMLHICAGIPVSLDDNFPDKMCSKCVRCLRLCYKFRLTCQRSHQHIMDMLDREASNANAAGEGDLLSIAEDLSVESVLKSWEDYASQLDGGMKVEGEEDQQHQVITYVVEDGDTDDTNMFDVHDPTQPVPNEIEEAETYAEYEEYELLTNENSPEIAQEKGSTGTDVATEEPPEEEIAEDILDSDEDYDPTHAKPEKCDRSGRKPVAYHKNSPKVETFKKKVGRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNYCQLPSPIDPRKPNIIEFTLRSVPTCATFAPERLPTRTT
Protein: Peroxiredoxin-5 (EC 1.11.1.24) (Q502C8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MPIKVGQRLPAVEVQEEDPGNSLSMAELFSCKRGVLFGVPGAFTPGCSKTHLPGFIQMAGELRAKGVDEVACISVNDVFVMSAWGKQNGADGKVRMLADPTGAFTKAVDLVLNNAQLIPVLGNLRSQRYAMLIENGVVTKLSVEPDGTGLTCSLASNFLAEV
Protein: Fatty acid-binding protein, liver (14 kDa selenium-binding protein) (Fatty acid-binding protein 1) (Liver-type fatty acid-binding protein) (L-FABP) (P12710)
Organism: Mus musculus (Mouse)
Function: Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
Subcellular location: Cytoplasm.
Interaction partners:
- Peroxisome proliferator-activated receptor alpha
- Apolipoprotein C-III
- Fatty acid-binding protein, intestinal
- Platelet glycoprotein 4
- Aspartate aminotransferase, mitochondrial
- Scavenger receptor class B member 1
- Apolipoprotein B-100
- Alpha-2-HS-glycoprotein
- Albumin
- Beta-2-glycoprotein 1
Sequence:
MNFSGKYQLQSQENFEPFMKAIGLPEDLIQKGKDIKGVSEIVHEGKKIKLTITYGPKVVRNEFTLGEECELETMTGEKVKAVVKLEGDNKMVTTFKGIKSVTELNGDTITNTMTLGDIVYKRVSKRI
Protein: Multiple C2 domain and transmembrane region protein 14 (Q9SS68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Vesicle {ECO:0000269|PubMed:29259105}. Golgi apparatus membrane {ECO:0000269|PubMed:29259105}; Multi-pass membrane protein {ECO:0000255}. Note=Localized in small structures within cells. {ECO:0000269|PubMed:29259105}.
Interaction partners:
- 16 kDa phloem protein 2
Sequence:
MADNVLRKLIVEICSARNLMPKDGQGTASAYAIVDFDGQRRRTKTKFRDLNPQWDEKLEFFVHDVATMGEEILEINLCNDKKTGKRSTFLGKVKIAGSAFASAGSETLVYYPLEKRSVFSQIKGEIGLKAYYVDENPPAAPAATEPKPEAAAATEEKPPEIAKAEDGKKETEAAKTEEKKEGDKKEEEKPKEEAKPDEKKPDAPPDTKAKKPDTAVAPPPPPAEVKNPPIPQKAETVKQNELGIKPENVNRQDLIGSDLELPSLTRDQNRGGGYDLVDRMPFLYIRVAKAKRAKNDGSNPVYAKLVIGTNGVKTRSQTGKDWDQVFAFEKESLNSTSLEVSVWSEEKIEKEDKTTTTTESCLGTVSFDLQEVPKRVPPDSPLAPQWYTLESEKSPGNDVMLAVWLGTQADEAFQEAWQSDSGGLIPETRSKVYLSPKLWYLRLTVIQTQDLQLGLGSEAKSKIPTTELYVKAQLGPQVFKTARTSIGPSASSSGSGNPTWNEDLVFVASEPFEPFLIVTVEDITNGQSIGQTKIHMGSVERRNDDRTEPKSRWFNLAGDEKKPYSGRIHVKVCLEGGYHVLDEAAHVTSDVRPSAKQLAKPPIGLLEVGIRGATNLLPVKTRDGTRGTTDAYVVAKYGPKWIRTRTILDRFNPRWNEQYTWDVYDPCTVLTIGVFDNGRYKRDESGKQGRDVRVGKIRVRLSTLDMNRIYLNSYTLTVILPSGAKKMGEVEIAVRFSCPSWLSIIQAYVTPMLPRMHYVRPLGPAQQDILRHTAMRIVTARLARSEPPLGQEVVQYMLDTDNHVWSMRRSKANWFRVITFLSRAATIARWIHGIRTWVHPPTTVLVHLLLVAIVLCPHLVLPTVFMYAFLILALRFRYRGRVKVNSVDPRLSCVDSVAPDELDEEFDGFPTTRQPEVVRIRYDRLRALAGRAQTLLGDVAAQGERVEALFNWRDPRATCIFVVFCLFASFLFYIVPFKVFLLGSGFYYIRHPRFRDDMPSVPVNFFRRLPSMSDQIL
Protein: Angiopoietin-related protein 6 (Angiopoietin-like protein 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5) (Q8NI99)
Organism: Homo sapiens (Human)
Function: May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Cadherin-1
Sequence:
MGKPWLRALQLLLLLGASWARAGAPRCTYTFVLPPQKFTGAVCWSGPASTRATPEAANASELAALRMRVGRHEELLRELQRLAAADGAVAGEVRALRKESRGLSARLGQLRAQLQHEAGPGAGPGADLGAEPAAALALLGERVLNASAEAQRAAARFHQLDVKFRELAQLVTQQSSLIARLERLCPGGAGGQQQVLPPPPLVPVVPVRLVGSTSDTSRMLDPAPEPQRDQTQRQQEPMASPMPAGHPAVPTKPVGPWQDCAEARQAGHEQSGVYELRVGRHVVSVWCEQQLEGGGWTVIQRRQDGSVNFFTTWQHYKAGFGRPDGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGARAHYDGFSLEPESDHYRLRLGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYQRGGWWYHACAHSNLNGVWHHGGHYRSRYQDGVYWAEFRGGAYSLRKAAMLIRPLKL
Protein: O-fucosyltransferase 39 (O-FucT-39) (EC 2.4.1.-) (O-fucosyltransferase family protein) (Q0WUZ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MNPYDAKDRRWILSMFFFVVLFCNNVSTSSSSSEVITIKPRHLSLLKSALQRSSGEQSDLWRPLTDQGWSPCIDLGNSPSLPDKTAGYVQVFLDGGLNQQRMGICDAVAVAKILNATLVIPYLEVNPVWQDSSSFVDIFDVDHFIDSLKDDIRVVRELPDEYSWSTREYYGTAVRETRVKTAPVHASANWYIENVSPVLQSYGIAAISPFSHRLSFDHLPAEIQRLRCKVNFQALRFVPHITSLGDALVSRLRNPSWRSNKEQKNVDHLGDMTNPHRRQEPGKFAVLHLRFDKDMAAHSACDFGGGKAEKLSLAKYRQMIWQGRVLNSQFTDEELRSQGRCPLTPEEMGLLLAAFGFDNNTRLYLASHKVYGGEARISTLRQVFPRMEDKRSLASSEERARIKGKASLLAALDYYVSMHSDIFISASPGNMHNALVGHRTFENLKTIRPNMALIGQLFLNKSITWVDFQQALGEGHVNRQGQIRLRKPKQSIYTYPAPDCMCHV
Protein: pH-response regulator protein palI/RIM9 (Regulator of IME2 protein 9) (Q04734)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- pH-response regulator protein palF/RIM8
- pH-response regulator protein palH/RIM21
- Protein DFG16
- pH-response transcription factor pacC/RIM101
- pH-response regulator protein palA/RIM20
- Calpain-like protease 1
- Uncharacterized protein YGR122W
- Vacuolar-sorting protein SNF7
Sequence:
MVSMIHIVVFLLAITTMFEILPLITVPVTKYLSLSSFRNHYYGLFGWCVRGQNQELMCTKMKIGYDSTDVDSSGHVLTLPSNSKVVVSNLLVVHPISLAFTGTLLILAVIIMVTPLGDSPEMLLFTALFSLPTFMLCLLCFLVDILLFISKLDWPGWLMLAATISVALCCSMLWVMRRVVSVKKYESQQSIAHACSMEQYSISDIYQSKQNGNSSEYEVAPTHTDSLIAPEVTYRGFIE