Protein: Pre-mRNA splicing factor (Prp8), putative (Q4WI55)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- 116 kDa U5 small nuclear ribonucleoprotein component
- Pre-mRNA-splicing ATP-dependent RNA helicase prp28
- RNA helicase
- U5 snRNP complex subunit, putative
- mRNA splicing factor
- Small nuclear ribonucleoprotein Sm D2
- Spliceosomal protein DIB1
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein Sm D1
Sequence:
MASLPPPPPPGWGAAPPSMPLAPPPPGYQPPADPNVAKFAQKKNEWLRTQRNRFGEKRKGGFVETQKADMPPEHLRKIVRDIGDVSQKKFSNEKRSYLGALKFMPHAVLKLLENMPMPWESAREVKVLYHVNGCLTLVNETPRVIEPVFHAQWATMWVCMRREKCDRRHFKRMRFPPFDDEEPPLSWSENIEDVEPLEPVQMELDESEDAPVYEWFYDHRPLLDTPHVNGPSYKSWNLTLPQMATLYRLSHQLLSDVVDQNYFHMFDLNSFLTAKALNVAIPGGPRFEPLYKDIDPNDEDFSEFNAIDRIIFRAPIRTEYRVAFPFLYNTLPRSVKVSWYSHPQVVYVRADPNLPAFYFDPVINPISSRSVAPKNITVSHEDEIFGPGNNEDDFELPPEVKPFFADEELYTPDTASAIALWWAPHPFNKRSGKMVRAQDVPLVKQWYLEHCPQGQPVKVRVSYQKLLKTYVLNELHKKKPKAQNKQNLLRTLKSTKFFQQTTIDWVEAGLQVCRQGFNMLNLLIHRKNLTYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLMREILRLTKLIVDAQVQYRLGNIDAFQLADGILYAFNHVGQLTGMYRYKYKLMHQIRSCKDLKHLIYYRFNSGPVGKGPGCGFWAPAWRVWLFFMRGIIPLLERWLGNLLSRQFEGRHSKGVAKTVTKQRVESHFDLELRASVMADLMDMMPEGIKQNKVNTVLQHLSEAWRCWKSNIPWKVPGLPAPIENIILRYVKSKADWWISVAHYNRERIRRGATVDKTVAKKNLGRLTRLWLKAEQERQHNYLKDGPYVSSEEAVAIYTTMVHWLESRKFSPIPFPSVSYKHDTKILILALERLREAYSVKGRLNQSQREELALIEQAYDSPGTTLARIKRFLLTQRAFKEVGIDMNDNYSHINPVYDVEPIEKITDAYLDQYLWYQAEQRHLFPAWIKPSDSEVPPLLTYKWAQGINNLSNVWETADGETNVMIETELSKVYEKIDLTLLNRLLRLIMDHNLADYITSKNNVQLSYKDMNHTNSYGLIRGLQFSGFVFQYYGLMIDLLLLGLQRASEMAGPPQSPNDFLQFRDRATETRHPIRLYTRYVDKIWVFFRFTADESRDLIQRFLTENPDPNFENVIGYKNKKCWPRDCRMRLMRHDVNLGRAAFWDLKNRLPRSITTIEWDDTFASVYSKDNPNLLFSMCGFEVRILPKIRNQNEEFSVKDSVWSLVDNATKERTAHAFLQVTEEDIQKFNNRIRQILMSSGSTTFTKIANKWNTALIALFTYYREAAVSTVNLLDTIVKCETKIQTRVKIGLNSKMPSRFPPAVFYTPKELGGLGMISGSHILIPASDKRWSKQTDTGITHFRAGMSHDEETLIPNIFRYIIPWEAEFIDSQRVWMEYSQKRMEAQQQNRRLTLEDLEDSWDRGLPRINTLFQKDRSTLSFDKGFRLRAEFKQYQLMKSNPFWWTSQRHDGKLWNLNAYRTDVIQALGGVETILEHTLFKATAFPSWEGLFWERACLAKGTRLLRYDGSEIEVQDVKEGDLLLGPDGGPRRAFNIVNGKDRLYRIKIGGSKEDLVVTPNHILVLHREKRARNVYTGPSVQGHIQRSENGHGNLPMLSSSPAAAHHPNNLVKNRGDFWSALKSAIAWVLHAERSSTGANMVRNVLNGTVGLTAHKESYTVTNPQQKGVYYTYVWGNPQRTSIKGHRDHPPVFLPTKEDAFSAAIAKSRELYSQSEVTLATLRQRFLAKSADGKGGEILVDANLPNIFLLWDKNRSNLKFRVLCSRNFKTYGRVYTFESMPSTNAEEPGYGDDDELPQVSAEERYDTVEMTAAEFASLSTEERSRYRVFRCPGFELPEQPVPVNPYFLGLWLGDDNHEKTTNHNIHEENVREFLVNHAAELDMYLAWQGLIDYATVANPAPMMVRLPPTNPDTIEHRPVVCQARQSIRKLRLAAKNIAQPEVVLSTSPRPESQMQPKRELPSNTETALRSEAEASSISAILDSKAGHSSLDTGDPNSDVVPESIPNDVADFGLDGVPELTSSGFSELTSDSELMRLIEQVERSSQGSTEEPSQASVVEQEADLNLLETDSEDEEADSADDDEFGDPEASEFRPEPESQLSQSHFSNRRRNHRLRTGRRVYGDLNGEEEGILLDQIVEQSEGSRVNSLLRALDALGIIAQKGTGPETNRKHIPSIYMKNSRSVRLAVLAGLIDSDGWYVYPENVLGFAQSERWHSKLFWDVVALARSLGLSVLTKRRMMWNPARTERYPQLFAQISGNVAEVPCLIARKKGVERLIPQTHSFMIKDISLEPEATEWAGFRVDKDQLYLRHDYLVLHNSGFEESMKFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFLHGKIPTLKISLIQIFRAHLWQKIHESVVMDLCQVFDQELEQLGIEAVQKETIHPRKSYKMNSSCADILLFATNKWNVTRPSILFDTKDVYEPTTTNKFWLDVQLRYGDYDSHDIERYVRAKYLDYTTDSMSIYPSATGLMIGIDLAYNLYSAYGQYFPGLKTLIQQAMAKIMKANPALYVLRERIRKGLQLYASESNQEFLNSQNYSELFSPQIQLFIDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQLIVTRKGLLDPLEVHLLDFPNISIRASELQLPFQAAMKVEKLADMILRATEPQMVLFNLYDEWLKSISPYTAFSRLILILRALHVNIDKAKIILRPDKTVITQEHHIWPTLSDEDWIKVEVQLRDLILNDYGKKNNVNVQSLTSSEVRDIILGMEISAPSLQRQQAAEIEKQQEEAKQLTAVTTKTQNVRGEEIIVTTTSQYEQQSFASKTEWRTRAIATSNLRTRANNIYISSDDVSEEGYTYIMPKNILRRFITIADLRVQVAGYLYGSSPPDNDQVKEIRTIVMIPQVGNTRDVQLPQQLPQHEYLNGLEPLGIIHTISGNEPHYMTAMDVTQHARLMNAHPSWDKKTVTMTVSFTPGSVSLAAWGLTPQGYKWGAENKDTTSDQPQGFSTSMGQKCQLLLSDKIRGYFLVPEDNVWNYSFMGSSFSSVEKRPVYVKIDTPLRFYDDQHRPLHFQNFAELEDIWVDRSDNFA