wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein, isoform B (Uncharacterized protein, isoform C) (Q8IQT4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform B
- ENL/AF9-related, isoform B
- GEO12084p1
- Protein benign gonial cell neoplasm
- E3 ubiquitin-protein ligase RING1
Sequence:
MEPNRHHEYQTHHQPHPSMQHHPTHPHHQQPHHQQPHHPQQPIHQHHPPPPPPQPQQQHQPPQQIHQQQQQHPHHYQQLHHHPTSSTSVGSSSSASYVNHHPQHHPTSLAEDQRGSRSAIYMSRSTQPGLPPPHPHSSAQGSGAAGTSGSDPHMQYYTSNQNLAIKKMSDPHPMWSYKSQAVTTPAPAPGLRQHGNPALYPTGSTAYWPPPDEQLHHQQPSRYSYAKPGGPVTGSRPIQGPLPNSQRYYSEDIKYSTVPAASKVLTYAPPASSSQPQPPPPTSSSSANSSSVRHYELDVVNPSNPSNEHQQPSPNYGRKCPPHYETPPEQRSAGATPNSTGTPTSTSHHQSLYIPMPTFSTEKFQTTVHNAIEKYIRETPGPSLEYPRGGVAPVGRTGYYNQQPMKSSKAPPSVPQTATSSYVKMEPEHALAGGLPQPTRSSLYHNPYNVESRERDSSPAMATVPAPHGYPTKYGKLIQQQHAASGVGTGSSAPYQSYYHQGTPSPAAGAVASPTPAPLPPLAEAPGTIFGPGTGLNPGIPPHSSQPVPPPANSQQPASSSSSSNANFSTLQVYPHGPDICYQPGSQTQAQNQTQNHPNPAKKSPAVTKPNYRALINDMLKRNTASEQELNLQIIKKTLNMEPASSRNHSAPSRVIQQSAAPAAISIPSAPPPPPPAIHSPLDLSMRTVKQTADSTEYKYQRPSTDYKLPQGGLGGGLGLPRFDITPNFSAATRGGAPTSPAPTPVIRQAVAIQPAPVPPTVPVPPAVAAPALVIKTVQQMRPSVVETNPFAKRQQQLPPETSIVQVTKPTVELMPTPSPSPHNSSNPNYLGKKRHLQEYNQAAAKQARLDAESSGSLVSGAPVIAAPTSVVVVAPVPVIAVNEQALAAKREREMQSMSAESSTSAHLVPKMEPRIRTKAELKGFTFTPPVLVTSTTNASSTISPPRTPPNQITNHIQIKLEPAPPKATDLGLDDEQHSLGNLMDWGSTCNNLVEQLMSKVVVPPTLPANNPGIKLELSEDDLPVARILKRQPLAAPSLAGGDAESATTQLTTTTNGISSSLGNGSGQKKLSKVEREKKRQQQEQRIAARLAPKQGQSSSSESDTTELHKRNTARQKKPLLRKGRTRQRSPEAASIQQSSDEEQEKVSQRLSRKPRTSSEESKTKATSAKKDVKKEAKTPSNKTNNSASLTKIKKKTTDSSSLNKAKGDENPKQESQESTSSESDQDDNDNDNDEEEEDQEEDEEEPEEEDDDEEQDKKKEKRVGRRPGNTLKKRIAHKLNTMTRSKHRKELELQLANSKVLRNDKIIRNSTTKIKRKYVRKVVDSKKEMMVTRLRNKRGMNSDLGALNGRNSKLKGSKVGNSPGKPKTSPQQQLYLEEYRYKLALKIPHSLISINKLNKVASSLPDLERRDLSQELACFKRNRPKTKAASKQDFTPKSIIDVLHLRVTNGSTAGTQRKISVSAPASTNLQIHSETSQTSASTSLYEQSQQDNPTENQSLDDMSKRHFSIFDTKVLQSKTRTETKLQKHREIIREIFVGPERPASAPPECVQEADGGDAISYQKYEEFLQQMNSIASANDSKLARRSLMEDKSVTAPQCPHKRKYRCRKGSSGFDYIRKKKRPAPTQTQNHTQNQSQSQVSSQITQHILEHNQSAADERLEDTDSTIAGSSHLPPKVKTEMDVCREIQKWVLNKGVGQSTMHKAARQGLIDVVVYCLDRMNMNPDQKDNAGYTPLHEACTQGWLEIARILLQYGANHSEAAQSGIRPLHGAIENDHEEVVRLLLSYGADPLLATYSGQTPLMLASSKLMRGILRAHLSDAQSAAADIKPMRFNGPWEIFDAKEYGYDIFSNVPNTACDMSRALRKERKEAKQQRMSSNSDRTSNLNGLLAEKKEEQKPEDLDQDRVTTTIKQNGETSATKTGSATTTTATTMVKLELGTDEDSNNNKNNEELNANVENNLVTSVVNVKNEVKKEVEAEAETEAETETNAKANTNSSTRLDEDQTDIETMDSELNGDIFEFEEADVPLPPLYLLKDEGSDKWVLLNDLCNLLKVKSKDTLLNKLCPNNSNALASSQKHLLREFKIDDFLEKATCLQLLCAGEKLNMFSSSKVVLIKYNDSVRNLLGVKTILMKF
Protein: Pre-mRNA-splicing factor PRP46 (Complexed with CEF1 protein 1) (PRP nineteen-associated complex protein 50) (PRP19-associated complex protein 50) (Pre-mRNA-processing protein 46) (Q12417)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in pre-mRNA splicing. May also be required for cell cycle progression at G2/M (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pre-mRNA-splicing factor CEF1
- Pre-mRNA-splicing factor CWC23
- Pre-mRNA-splicing factor 8
- U2 small nuclear ribonucleoprotein B''
- Pre-mRNA-splicing helicase BRR2
- Small nuclear ribonucleoprotein-associated protein B
- Small nuclear ribonucleoprotein Sm D2
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22
- Pre-mRNA-splicing factor BUD31
- Splicing factor YJU2
Sequence:
MDGNDHKVENLGDVDKFYSRIRWNNQFSYMATLPPHLQSEMEGQKSLLMRYDTYRKESSSFSGEGKKVTLQHVPTDFSEASQAVISKKDHDTHASAFVNKIFQPEVAEELIVNRYEKLLSQRPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLSAKRF
Protein: ATP synthase subunit gamma, mitochondrial (F-ATPase gamma subunit) (O74754)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular location: Mitochondrion. Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- ATP synthase subunit 5, mitochondrial
- Putative ATP synthase subunit epsilon, mitochondrial
- ATP synthase subunit alpha
- ATP synthase subunit a
- ATP synthase subunit d
- ATP synthase subunit delta, mitochondrial
- ATP synthase subunit beta, mitochondrial
- ATP synthase subunit 9, mitochondrial
- ATP synthase subunit 4
- ATP synthase subunit g, mitochondrial
Sequence:
MLRQTLTQASRMRPCISVVGFRGFHASSPCEATLKEIEQRLKSIKNIEKITKTIKTVAQTKLTRAQRAMEASNKYYRVSDEVFKEAGTKAPEEGKTLMVACSSDKGLCGGIHSSISRLIRRELHDPKTFENTSLCILGEKVRTQLLRFCPESFYLTFAHIGGASPSFEEALQISSNILEHAKDYDRIVLVYNKFASAVSFETVMKNLYTTKAINESPNLSAYEVSDEVHQPLMEFAFANAIFSAMAEAHCSEMSSRRNAMENASKSAGDMINKFSIQYNRQRQASITNELIDIVTGANSLA
Protein: Mitochondrial transcription factor 1 (EC 2.1.1.-) (Mitochondrial transcription factor mtTFB) (Mitochondrial-specificity factor) (RF1023) (P14908)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.
Subcellular location: Mitochondrion intermembrane space {ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:22984289}.
Interaction partners:
- DNA-directed RNA polymerase, mitochondrial
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein bS16m
- Ribosome assembly protein RSM22
- Essential nuclear protein 1
- Mitochondrial translation factor 2
- Non-histone chromosomal protein 6A
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein uS10m
Sequence:
MSVPIPGIKDISKLKFFYGFKYLWNPTVYNKIFDKLDLTKTYKHPEELKVLDLYPGVGIQSAIFYNKYCPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRDPYDWSTYSNLIDEERIFVPEVQSSDHINDKFLTVANVTGEGSEGLIMQWLSCIGNKNWLYRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTDTKLIAISDANELKGFDSQCIEEWDPILFSAAEIWPTKGKPIALVEMDPIDFDFDVDNWDYVTRHLMILKRTPLNTVMDSLGHGGQQYFNSRITDKDLLKKCPIDLTNDEFIYLTKLFMEWPFKPDILMDFVDMYQTEHSG
Protein: Methylcrotonyl-CoA carboxylase, alpha-subunit (Biotin-containing) (Q9I299)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Methylcrotonyl-CoA carboxylase, beta-subunit
- 3-methylglutaconyl-CoA hydratase
- 3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase
- Probable transcarboxylase subunit
- Probable pyruvate carboxylase
- Geranyl-CoA carboxylase, beta-subunit
- Isovaleryl-CoA dehydrogenase, mitochondrial
- Regulator of liu genes
- Fatty acid oxidation complex subunit alpha
- Probable 3-hydroxyacyl-CoA dehydrogenase
Sequence:
MNPDYRSIQRLLVANRGEIACRVMRSARALGIGSVAVHSDIDRHARHVAEADIAVDLGGAKPADSYLRGDRIIAAALASGAQAIHPGYGFLSENADFARACEEAGLLFLGPPAAAIDAMGSKSAAKALMEEAGVPLVPGYHGEAQDLETFRREAGRIGYPVLLKAAAGGGGKGMKVVEREAELAEALSSAQREAKAAFGDARMLVEKYLLKPRHVEIQVFADRHGHCLYLNERDCSIQRRHQKVVEEAPAPGLGAELRRAMGEAAVRAAQAIGYVGAGTVEFLLDERGQFFFMEMNTRLQVEHPVTEAITGLDLVAWQIRVARGEALPLTQEQVPLNGHAIEVRLYAEDPEGDFLPASGRLMLYREAAAGPGRRVDSGVREGDEVSPFYDPMLAKLIAWGETREEARQRLLAMLAETSVGGLRTNLAFLRRILGHPAFAAAELDTGFIARHQDDLLPAPQALPEHFWQAAAEAWLQSEPGHRRDDDPHSPWSRNDGWRSALARESDLMLRCRDERRCVRLRHASPSQYRLDGDDLVSRVDGVTRRSAALRRGRQLFLEWEGELLAIEAVDPIAEAEAAHAHQGGLSAPMNGSIVRVLVEPGQTVEAGATLVVLEAMKMEHSIRAPHAGVVKALYCSEGELVEEGTPLVELDENQA
Protein: Accessory gland-specific peptide 57Da (Male accessory gland secretory protein 57Da) (Q9VBL6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transferred from male to female during mating and may affect egglaying and behavior after mating.
Subcellular location: Secreted {ECO:0000269|PubMed:7711745}.
Interaction partners:
- Accessory gland-specific peptide 57Dc
- ACP53C14B
- ACP53C14A
- Accessory gland protein Acp53Ea
- Accessory gland-specific peptide 57Db
- Ejaculatory bulb-specific protein 2
- Accessory gland-specific peptide 26Aa
- Seminal fluid protein 24Bb
- GEO13347p1
- Serpin 38F, isoform A
Sequence:
MKFLALFVTLLVVLALVSAQKSQNTNHNVIVIGAKKPGAAPAAAAAAAPAAPPAAAPAAAPAAPEAGLADAPAES
Protein: CCAAT/enhancer-binding protein (Q7SZH5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005879}.
Interaction partners:
- Cyclic AMP-dependent transcription factor ATF-4
- Cyclic AMP-dependent transcription factor ATF-4
- Cyclic AMP-dependent transcription factor ATF-4
- C-myb C-terminal domain-containing protein
- DNA damage-inducible transcript 3 protein
- BZIP domain-containing protein.
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- Uncharacterized protein
- Runt-related transcription factor 2
Sequence:
MEVAGFYDRDCFAFQSTNCIIRPISDNSTCKQPIDGSMTELGIAENEKAIDFSVYLDPPAAHCQQLATQNETHQRGVDIFADFLAEESRIKRRSSLQQNYRNYISLNERETSVHDNREPYVLGYPELQETRVDTVFSPEFIGNHFKSGERDESQEDPRMDNGSTGYDMRYLHYQSTPSGSLGNISTASSSSSSPPGTPALSGKCTSPSRGGKMSSGVKGKKRLEKNSEEYKQRRERNNLAVRKSRDKAKMRNTETQHKVLELAAENDRLQKRVEQLSRELATLRNLLSATG
Protein: DNA ligase (EC 6.5.1.1) (Q5ZLW6)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAEQRYCVDYAKRGTAGCKKCKEKIVKGMVRIGKIVPNPFTESGGDMKEWYHVKCMFEKLEKARASTKKIEDITDLEGWEELQDGEKELITNFISEATSKAASTPKKKATVQAKLTATGQISSPQKDPLANVNPKKFSGFTAKPKNSEEVSANSSHNSSLSAKNCDPKHKDCLLREFRKLCAMVADKPSYNVKTQIIQDFLKKGSGGDGFHGDVYLTIKLLLPGIIKIVYNLNDKQIVKLFSRIFNCSQEEMVRDLEQGDVSETIRLFFEQSKSCPPAAKSLLTIQEVDEFLIQLSKLTKEDDQQSVLQDITRRCTGNDLKCIIRLIKHDLKMNAGAKHVLDALDPNAYEAFKASRNLQDVVERVLRNQQDAEKTPGVKRTLSVQASLMTPVQPMLAEACKSIEYAMKKCPNGMYAEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAHFKDFIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGSLGVHKKAAFQDANVCLFVFDCIYFNDISLMDRPLRERRKFLHDNMVEIPNPDPVLGDEARHKSFRSGRYDHRVIREGLEGLVLKDIKGNYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGKGSKGGMMSIFLMGCYDPTSEKWCTVTKCAGGHDDATLARLQTELDMVKISKDPSKIPSWLKINKIYYPDFIVPDPKKAPVWEITGAEFSKAEAHTADGISIRFPRCTRIRDDKDWKTATNLPQLKELYQLSKEKAEFSVVAGEEEESTAGSSGENEGNSRSSTPHKTTKTPPKSPAKAKKPEGTKAVTESPQKPEEKRGEKRKASEVEDNGKKMLLDIFTGVKLYLSPSVKDFNKIRRYFIAYDGDLVTEYDTASATHIIGDIDENPGAKRVSPKWIWECIRKRRLVAPC
Protein: Photoreceptor disk component PRCD (Progressive rod-cone degeneration protein homolog) (Q00LT2)
Organism: Mus musculus (Mouse)
Function: Involved in vision.
Subcellular location: Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:23672200, ECO:0000269|PubMed:27509380, ECO:0000269|PubMed:27613864}. Membrane {ECO:0000269|PubMed:27509380, ECO:0000269|PubMed:27613864}; Lipid-anchor {ECO:0000269|PubMed:27509380}; Cytoplasmic side {ECO:0000269|PubMed:27509380}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q00LT1}. Golgi apparatus {ECO:0000250|UniProtKB:Q00LT1}. Note=Localizes to photoreceptor disk membranes in the photoreceptor outer segment. {ECO:0000269|PubMed:27509380}.
Interaction partners:
Sequence:
MCTTLFLFSLAMLWRRRFTNRVEPEPSRVDGTVVGSGSDTDLQSTGREKGPVK
Protein: Putative galactoside 2-alpha-L-fucosyltransferase svh-11 (EC 2.4.1.-) (Suppressor of vhp-1 deletion lethality protein svh-11) (Q966A0)
Organism: Caenorhabditis elegans
Function: Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids (By similarity). Required for axon regeneration after injury.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- UAA transporter
- Xylosyltransferase sqv-6
- Beta-1,4-galactosyltransferase galt-1
- Xylosylprotein 4-beta-galactosyltransferase
- UDP-glucuronate decarboxylase
Sequence:
MRLFHFLKFLTINNFSRYCLKIVKVHIIWITIICIIYFNWRFKKLDFMAIPYPPAVIKFNTSAKYLSSNLASSSQLGNNIFEIASLYGLSKHLNRTPLFFIENGYHKKMLDNLRKTMPRLMEKFRILNGSVPRSISETKFQRACCLHKSPWSLEKNRDEYLHLSGKYYQSWKYFPNMRNELIEFLNPTSIQIFGNLPISDDQNHVTCVHSRRGDFVEYLFYASDPKFMKNAVTFLNENEKVGSRNRKIVLFGDDLNFLETYFSDAVLSTDVGKNAEYYISQNPPIDDFLYSKNNCDVVLITAPRSTFGWWIGYFSKGNKVYYLDIKYTGDHIFESGGLIASDFYPSHWTPLKFASANSFTVVRS
Protein: TEL2-interacting protein 1 (O94600)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- RuvB-like helicase 1
- DNA replication checkpoint protein tel2
- RuvB-like helicase 2
- ASTRA-associated protein 1
- SAGA complex/NuA4 acetyltransferase complex subunit Tra1
- Serine/threonine-protein kinase tor1
- Heat shock protein 90 homolog
- Serine/threonine-protein kinase tor2
- Tel2-interacting protein 2
- NuA4 acetyltransferase complex subunit Tra2
Sequence:
MSHIQSIFAQIRDPFRKLSFYSLPLSSETSSVDSNGLKNSLKDAYFGLEKALTNTDADLPLNLCDYIFFPIVPVLKSWYRVPSTGVEYAIQCVNLLYKHGWREAHNEMLTMQLLLMLLNIADGWKSPSETVEQDFRVREITFETLENVITDFKPNFHDKRQYLLFARALSSALDIIPNKNSSRRLQFASLCCVQKLICPKQYRLPTEFLTTFLPGIVSGLTKGLAPNGTCQYFKNVCISLNILGDTVVKAISDDNTKDLPDEKDASSNSHFFGPTKRTKSWKRATCQQLSNAVKAILHLRSSQNLHVQDALFDFCFILFRDCLDSLKDCRIHLLESMLKLINKKENPKLRDYGMNKLVSLIESFNNITMESVLTECLNDWSTTWSSVSTFASEDNKLEELNRLKSLLSISSHLPKTLQLMEPLLDGILSQLVPKSSGIDSNSQKLLTSSTSNEYIHGEFFGGNEMERTTQEIVTSFAKAPNVKYVMQSLLSKATSATNENSVRAFWAFMVLLKSDVETVDSLEMYIDSLEQYSFEVLQQLSQLNVFTKASLEDKQKKEKYNLLCVRSCIAIDSISWISSLQGVKFRSKLMAYFYPLLEHLAFASPYVSSFAEACIQAIATNCNYSTPAELLRENIDYVVNSVALKLNTLDVSPQLPIVMAYVIKNDDGGCIRYIGDVVDAIFGILDAYHGYARLTEGLLGILYAIIKQESINGEEKKLIVGVEEDAMNEDKNKPCKKIREFVQLLLENPNYPLPKDDHELEDMIHDEQQETKSGHEQFREHAMKEKEKKGKENENMGETTVDHENINSNVMDEQGEKQKDDVVDMVRKITEKAQLFLSHEQITIRVEMLKLLSYGSNVLAKEPNTFYPAINTFWPLVVIQLDTDNELLVECALETIYQVCALADDFMTSRIRQDLLPRLETLCQRWHLFNVARTYSSEHRLQRAMLKVTSACVANKLSIVVYLKLMGITAPIIRAITHMSQKYAGDESLVEETWNAFSKQNPDAVYYEREVRGSQMIDTFSTELLIPGKQRVQRTYRRTHEVLEPVGAKTSETVFNDLLGQQGSGKTETQEEPLPSLDNLLHLNQPKKGAKKPLISII
Protein: Putative colanic acid biosynthesis acetyltransferase WcaF (EC 2.3.1.-) (P0ACD2)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Putative colanic acid biosynthesis glycosyl transferase WcaI
- Putative colanic acid biosynthesis glycosyl transferase WcaE
- Putative colanic acid biosynthesis glycosyl transferase WcaC
- Putative colanic acid biosynthesis acetyltransferase WcaB
- Putative polysaccharide export protein Wza
- GDP-L-fucose synthase
- Putative colanic acid biosynthesis glycosyl transferase WcaA
- GDP-mannose 4,6-dehydratase
- GDP-mannose mannosyl hydrolase
- Putative colanic acid polymerase
Sequence:
MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRAFLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDDVNLYTLGEITIGAHSVISQKSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKSLPANVVCRGNPAVVIRERVETE
Protein: Ribonucleases P/MRP protein subunit POP1 (hPOP1) (Q99575)
Organism: Homo sapiens (Human)
Function: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:8918471}.
Interaction partners:
- Ribonuclease P/MRP protein subunit POP5
- Ribonuclease P protein subunit p14
- Ribonuclease P protein subunit p21
- Ribonuclease P protein subunit p29
- Ribonuclease P protein subunit p30
- Ribonuclease P protein subunit p25
- Ribonuclease P protein subunit p20
- Ribonuclease P protein subunit p38
- Ribonuclease P protein subunit p40
- Ribonuclease P protein subunit p25-like protein
Sequence:
MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV
Protein: Branched-chain amino acid ABC transporter, ATP-binding protein (Q5LV80)
Organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Interaction partners:
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, periplasmic substrate-binding protein
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Efflux ABC transporter, ATP-binding protein
- Peptide synthase
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, permease/ATP-binding protein
Sequence:
MAACSTRRAPMLEIDGLTARYGRAQILNGVSLTLGRNEVVALLGRNGAGKSTTMKSVMGLVRQTGGSIRLDGTNILGRASHLICRAGIGYVPEDRRIFGELTVEENLEVGRRPAREGAPHWSADHLFQLFPNLAERRQNLGKQLSGGEQQMLSIARTLMGNPALVLLDEPSEGIAPVIVEQMANVISELKREGLSVLLSEQNLHFAREVSDRAYIIEKGTMRYEGDFADLDARPEVSAQYLAV
Protein: Heat shock factor protein 1 (HSF 1) (HSF 3A) (HSTF 3A) (Heat shock transcription factor 1) (HSTF 1) (P38529)
Organism: Gallus gallus (Chicken)
Function: Functions as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones heat shock proteins (HSPs) that protect cells from cellular insults' damage. In unstressed cells, is present in a HSP90-containing multichaperone complex that maintains it in a non-DNA-binding inactivated monomeric form. Upon exposure to heat and other stress stimuli, undergoes homotrimerization and activates HSP gene transcription through binding to site-specific heat shock elements (HSEs) present in the promoter regions of HSP genes. Upon heat shock stress, forms a chromatin-associated complex with TTC5/STRAP and p300/EP300 to stimulate HSR transcription, therefore increasing cell survival (By similarity). Activation is reversible, and during the attenuation and recovery phase period of the HSR, returns to its unactivated form. Binds to inverted 5'-NGAAN-3' pentamer DNA sequences. Binds to chromatin at heat shock gene promoters. Also serves several other functions independently of its transcriptional activity. Involved in the repression of Ras-induced transcriptional activation of the c-fos gene in heat-stressed cells. Positively regulates pre-mRNA 3'-end processing and polyadenylation of HSP70 mRNA upon heat-stressed cells. Plays a role in nuclear export of stress-induced mRNA. Plays a role in the regulation of mitotic progression. Also plays a role as a negative regulator of non-homologous end joining (NHEJ) repair activity in a DNA damage-dependent manner. Involved in stress-induced cancer cell proliferation.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q00613}. Cytoplasm {ECO:0000250|UniProtKB:Q00613}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q00613}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q00613}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q00613}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q00613}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:Q00613}.
Interaction partners:
- Heat shock factor-binding protein 1
- Prostaglandin E synthase 3
- Heat shock cognate 71 kDa protein
- Mitogen-activated protein kinase.
- Elongation factor 1-alpha 1
- Glycogen synthase kinase 3 beta
- DnaJ heat shock protein family
- non-specific serine/threonine protein kinase
- F-box/LRR-repeat protein 8
- Heat shock protein HSP 90-alpha
Sequence:
MEGPGAAAAAVGAGPGGSNVSAFLTKLWTLVEDPETDPLICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPEKDDTEFQHPYFIRGQEHLLENIKRKVTSVSSIKNEDIKVRQDNVTKLLTDIQVMKGKQESMDSKLIAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSSSAHSMPKYSRQYSLEHVHGSSPYAASSPAYSGSNIYSPDSSTNSGPIISDVTELAQSSPSASPSGSLDERSSPVVRIKEEPPSPSRSPKENEPSTTTAAAGNSTEQPQPQEKCLSVACLDKNELNDHLDTIDSNLDNLQTMLSTHGFSVDTTALLDLFSPSMTVTDMNLPDLDSSLASIQDLLSSQEQQKPSEADAAAADTGKQLVHYTAQPLFLVDSSAVDVGSGDLPIFFELGEGSYFTDGDEYNEDPTISLLSGTEQPKPKDPTVS
Protein: Forkhead box P3 (D4Q8I3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPNPRPAKPMAPSLAPGPSPGGLPSWKTAPKGSELLGTRGPGGPFQGRDLRSGAHTSSSSLNPLPPSQLQLPTVPLVMVAPSGARLGPSPHLQALLQDRPHFMHQLSTVDAHGHTPVLQVRPLDNPAMIGLPPPTAATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPRSGTPRKDSNLLAAPQGSYPLLANGVCKWPGCEKAFEEPGEFLKHCQADHLLDEKGKAQCLLQREVVQSLEQQLELEKEKLGAMQAHLAGKMALTKAPPVASVDKSSCCLVATSTQGSVLPAWSSPREASDSLFAVRRHLWGSHGNSTFPGHPGSSREAEDTQ
Protein: Phospho-2-dehydro-3-deoxyheptonate aldolase AroG (EC 2.5.1.54) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) (DAHP synthase) (Phospho-2-keto-3-deoxyheptonate aldolase) (O53512)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate.
Interaction partners:
- Intracellular chorismate mutase
- 3-dehydroquinate synthase
- Chorismate synthase
- Secreted chorismate mutase
- 3'-5' exoribonuclease Rv2179c
- Probable conserved integral membrane protein
- Polyprenol-phosphate-mannose-dependent alpha-
Sequence:
MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD