wanglab/gogpt-training-data huggingface dataset:
Protein: MKIAA4151 protein (Q571K1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
KKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGPLNTDVAPGAPQEKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRLEHSEWESARTPIMGACGSQEQALLIDLPGHSCRRTRSGAGWKRVLRSLCHSRTRVPLLAAIYFLMIHVLLVLCFTGHL
Protein: Stomatal closure-related actin-binding protein 1 (O48791)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant-specific actin binding protein that bundles and stabilizes microfilaments (MFs). Has no nucleation or capping activity. Regulates MF reorganization during stomatal closure. The binding to F-actin is insensitive to Ca(2+) and pH. Binds weakly to inositol phosphates.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21719691}.
Interaction partners:
- Actin-related protein 3
- Casein kinase 1-like protein 2
- Protein WVD2-like 7
- AP-3 complex subunit mu
- Wee1-like protein kinase
- F10B6.17
- Actin-related protein 2
- At5g19590
- Actin-depolymerizing factor 4
- Uncharacterized protein
Sequence:
MTRVTRDFRDSLQRDGVPAVSADVKFASSRFPNYRIGANDQIFDVKDDPKVMSMKEVVARETAQLMDQQKRLSVRDLAHKFEKGLAAAAKLSEEAKLKEATSLEKHVLLKKLRDALESLRGRVAGRNKDDVEEAIAMVEALAVQLTQREGELFIEKAEVKKLASFLKQASEDAKKLVDEERAFARAEIESARAAVQRVEEALREHEQMSRASGKQDMEDLMKEVQEARRIKMLHQPSRVMDMEYELRALRNQLAEKSKHFLQLQKKLAMCRKSEENISLVYEIDGTEALGSCLRVRPCSNDAPDLSKCTIQWYRSSSDGSKKELISGATKSVYAPEPFDVGRVLHADIIYDGHSLSLSTVGKIDPAAGLGSYVEALVRKHDVDFNVVVTQMSGEDHTSESIHLFHVGKMRIKLCKGKTVIAKEYYSSAMQLCGVRGGGNAAAQALYWQAKKGVSFVIAFESERERNAAIMLARRFACDCNVTLAGPEDRTETGQSP
Protein: E3 ubiquitin ligase Rnf157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase Rnf157) (M0R5D6)
Organism: Rattus norvegicus (Rat)
Function: E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons (By similarity). Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical (By similarity). May act as a scaffold molecule to regulate this process (By similarity). Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25342469}.
Interaction partners:
- Modulator of smoothened.
- Multiple epidermal growth factor-like domains protein 8
- Attractin-like protein 1
Sequence:
MGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDCTHPEGYLFGENSDLNFLGNRPVSFPYAAPPPHEPVKTLRSLINIRKDTLRLVKCAEEVKSHGEEAGKAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVHYKRGVCQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVLLGTFEKHSDGTFCVKPLKQKQVWDGVTYLLQEDYGIENKSNTQDFKVAEDDVRDNSAECVVCLSDVRDTLILPCRHCASCNVHCADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPSSFNPIISSQTSDSEEHSSSENIPAGYEVVSLLEALNGPLTSSPAVPPLHVLGDGHLSGMLPSYGSDGHLPPVRTLSPLDHLSDCNSQGLKLNKSLSKSISQNSSVLHEEEDERSCSESDTQLSQRLSAQHPEEGPDVTPESENLTLSSSGAVDQSSCTGTPLSSTISSPEDPASSSLAQSVMSMASSQISTDTVSSMSGSYIAPGTEEEGEAPPSPRAASRAPSEEEETPAESPDSNFAGLPAGEQDAEGNDIMEEEDRSPVQEDGQRTCAFLGMECDNNNDFDVASVKALDNKLCSEVCLPGTWQHDAAIINRHNTQRRRLSPSSLEDPEEDRPCVWDPLAV
Protein: Formate hydrogenlyase subunit 7 (FHL subunit 7) (Hydrogenase-3 component G) (P16433)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Formate hydrogenlyase subunit 4
- Formate dehydrogenase H
- Formate hydrogenlyase subunit 2
- Formate hydrogenlyase subunit 6
- Formate hydrogenlyase subunit 3
- Formate hydrogenlyase subunit 5
- Formate hydrogenlyase maturation protein HycH
- Hydrogenase 3 maturation protease
- Hydrogenase-4 component G
- Hydrogenase-4 component B
Sequence:
MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVDCGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQSAPDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMALGLLEQKIHARGPGELDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDYLTQLGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR
Protein: Zinc finger protein 175 (Zinc finger protein OTK18) (Q9Y473)
Organism: Homo sapiens (Human)
Function: Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
Sequence:
MPADVNLSQKPQVLGPEKQDGSCEASVSFEDVTVDFSREEWQQLDPAQRCLYRDVMLELYSHLFAVGYHIPNPEVIFRMLKEKEPRVEEAEVSHQRCQEREFGLEIPQKEISKKASFQKDMVGEFTRDGSWCSILEELRLDADRTKKDEQNQIQPMSHSAFFNKKTLNTESNCEYKDPGKMIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDTEQLDDVVGSGQLFSHSSSDACSKNIHTGETFCKGNQCRKVCGHKQSLKQHQIHTQKKPDGCSECGGSFTQKSHLFAQQRIHSVGNLHECGKCGKAFMPQLKLSVYLTDHTGDIPCICKECGKVFIQRSELLTHQKTHTRKKPYKCHDCGKAFFQMLSLFRHQRTHSREKLYECSECGKGFSQNSTLIIHQKIHTGERQYACSECGKAFTQKSTLSLHQRIHSGQKSYVCIECGQAFIQKAHLIVHQRSHTGEKPYQCHNCGKSFISKSQLDIHHRIHTGEKPYECSDCGKTFTQKSHLNIHQKIHTGERHHVCSECGKAFNQKSILSMHQRIHTGEKPYKCSECGKAFTSKSQFKEHQRIHTGEKPYVCTECGKAFNGRSNFHKHQITHTRERPFVCYKCGKAFVQKSELITHQRTHMGEKPYECLDCGKSFSKKPQLKVHQRIHTGERPYVCSECGKAFNNRSNFNKHQTTHTRDKSYKCSYSVKGFTKQ
Protein: N-acetylmuramoyl-L-alanine amidase AmiA (EC 3.5.1.28) (P36548)
Organism: Escherichia coli (strain K12)
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors.
Subcellular location: Periplasm {ECO:0000269|PubMed:12787347}. Note=Distributed throughout the periplasm in all cells.
Interaction partners:
- N-acetylmuramoyl-L-alanine amidase AmiB
- Oxygen-dependent coproporphyrinogen-III oxidase
- N-acetylmuramoyl-L-alanine amidase AmiC
- Murein hydrolase activator EnvC
Sequence:
MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDELLKTSNGHSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDARLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMAKYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKLHSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYFHWFDNQKAHSKKR
Protein: UBX domain protein 1 (E9PJ81)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPTSSEQGGLEGSGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRRRQGQELSAARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKREYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVELHRGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLI
Protein: RNA-binding protein RBP10, putative (Q57W93)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA-binding protein RBP6, putative
Sequence:
MGDSISPSELLPGHAGEEHFLSLEEGTTPQVHRQEVTTDAMTNLQRRNVYVSGLPETYRASEFRDLCQSFGRVEASKLCVDSKCRPAKGYGFALFFEEEDALKCIEGLNGRVLMGGRPLQARIADAAAAPAPLDPSIAHPPISRTRQGMKSHHRQLGASISSGSGPLDSSIVLGRSMSFSSRDDLTGSQLGLATALIPGTGTPSAPTALHAPMQAPIHGAGVTQPPGAVGYSLAPFPVPGGYMPVGHSFIPQQTVGMPLFVTMPQTAPVSTTVAQQVVVPTTAIVAPNGYTPQLCSSLVYPPVRME
Protein: Bi-functional coumaroyl CoA and feruloyl CoA ortho-hydroxylase Diox4 (EC 1.14.11.61) (EC 1.14.11.62) (2-oxoglutarate-dependent dioxygenase 4) (2OGD Diox4) (W5QJZ5)
Organism: Ruta graveolens (Common rue)
Function: 2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD) involved in scopoletin and umbelliferone biosynthesis. Converts feruloyl CoA into 6'-hydroxyferuloyl CoA, and p-coumaroyl CoA into 2,4-dihydroxycinnamoyl-CoA. Has no activity with cinnamic acid, caffeic acid, p-coumaric acid, ferulic acid, cinnamoyl-CoA and caffeoyl-CoA.
Interaction partners:
Sequence:
MAPTKDSVIHMGAESWDEISEFVTKKGHGVKGLSELGIKTLPKQFHQPLEERFSEKKILERASIPLIDMSKWDSPEVVKSICDAAEHWGFFQIVNHGVPLETLQRVKEATHRFFALPAEEKNKYSKENSPINNVRFGSSFVPHVEKALEWKDFLSMFYVSEEETNTYWPPICRDEMLEYMRSSEVLIKRLMEVLVVKGLKVKQIDEIREPMLVGSRRINLNYYPKCPNPELTLGVGRHSDISTFTILLQDEIGGLHVRKLDDTGNTWVHVTPISGSLIINIGDALQIMSNGRYKSIEHMVVANGTQDRISVPLFVNPKPQAILCPFPEVLANGEKPVYKPVLCSDYSRHFYTKPHDGKKTVDFALMN
Protein: Uncharacterized protein (Q580X9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSVGVSDALEGSRQSKGRTGSIFSGEKMSTTTFGTRSATSLSMDAKASTARMSSTAERVVASNISPCPNVERLRNTAVEDRVLWHVRRRESLQQTKEREQRKIMMERRISMTDYYKTLFRLPPPNSRFNEQQGKAVALPVLQGPMTKAKEKMILESLPKFAHRRVVQDINDYFIAAYYKQNPEALVRKLEEEERQSRVAAATAAAAARNSPTRTGARSQSLGTPSRKNRGGKKKKKKQEVVEEGKPAPNLRLLQSALLTVADSSGIVTLDAFLDMLRQAPFEVRDDEAAENFFSVAHPSSSMSESGVNAVGRLETSHNTAAASSGVRSLSPLKAAQLHHASLHRTIEGSGAGQTSSSNMSVAKMSPVLAGNRGNQTFPIPGVNIPAPVVNETSQREKSPEAHVRELLAGFDALVNGAELKDVIRKLCFSVLETDDYIHKSALTQLRRDGRESCEEPESVLSPSIVKALRDSLDVLHQEEEQAYIRSQLKGRKNRKSVKAASLLPHQKTVIPLNMMRRSHISYEEFCRFFDTMPFLVAAFAHMWLPAFFAPTWPRRKRAASYGLYSDDQDMDDDYTAPTCQEGNEDGTTEEHRGVRDEVDWEKVATPPLRDVLLSALKRRHMASNIVANRLAFMNTTVESPSRASEASPVPS
Protein: Adrenodoxin-like protein 1, mitochondrial (Ferredoxin-1) (P37193)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition.
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- Iron-sulfur cluster assembly enzyme IscU
- LYR motif-containing protein 4 homolog
- Cysteine desulfurase, mitochondrial
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- NADH dehydrogenase 23 kDa subunit
- NADH-ubiquinone oxidoreductase chain 3
- NADH-ubiquinone oxidoreductase chain 4
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- Frataxin homolog, mitochondrial
Sequence:
MFCLLLRRSAVHNSCKLISKQIAKPAFYTPHNALHTTIPRRHGEFEWQDPKSTDEIVNITYVDKDGKRTKVQGKVGDNVLYLAHRHGIEMEGACEASLACTTCHVYVQHDYLQKLKEAEEQEDDLLDMAPFLRENSRLGCQILLDKSMEGMELELPKATRNFYVDGHKPKPH
Protein: Zinc finger and BTB domain-containing protein 42 (Protein simiRP58) (Q811H0)
Organism: Mus musculus (Mouse)
Function: Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18262495}. Nucleus, nucleoplasm {ECO:0000269|PubMed:21193930}. Note=In skeletal myofibers, highly enriched in subsynaptic nuclei at the neuromuscular junctions. {ECO:0000269|PubMed:21193930}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 25 homolog
Sequence:
MEFPEHGVRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDQPASSRDTVRLNGDIVTVPAFSRLLDFMYEGRLDLHNLPVEDVLAAASYLHMYDIVKVCKGRLRKKDPDLETRTLGTELPGQPPHPLPSWSPAFCQAAPKAKHPSLGVKATHPLPTFGPPSWQVAEQSSGALDLSLKPSPRPEQVHPPCRLQTSLCSSVQQVAQPLVKAEQDSFSEQDSSSPQSADRSPPPVCASAAQGLAVDLEPLHIEGTGSQQLGLPAEPVLDSEELGPSRHLCICPLCCKLFPSTHALQLHLSAHFRERDSVRARLSPEGSVPTCPLCSKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHAVVHTREKPHACRWCERRFTQSGDLYRHVRKFHYGLVKPLLV
Protein: E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650) (Q5U430)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May play a role in Shh signaling by mediating the ubiquitination of Kif7. May be important for MYH9 function in certain tissues, possibly by regulating the ubiquitination of MYH9 and consequently affecting its interaction with MYO7A.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative E3 ubiquitin-protein ligase UBR7
Sequence:
MAAAAAAAAVGDPQPPQPEAPAQGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLNAERPLAGAAGGEEAAGGGGGGPGEAEEDALEWCKCLLAGGGGYEEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCRRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADAPSEKDLNKVLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTAGLGENACAKKSHEKYLIALKSSGLTYPEDKLVYGVQEPAAGTSTLAAQGFAGATGTLGQIDSSDEEDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAQRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDEPAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSLLPDQEMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHHNMVLDVEHERSMLEGALTFLVILLSLRLHLGMSDDDILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFRAPIFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFPGNPWPPYKKRTSLHPSYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLENSADDDSEEEVSMGGPERCHDSWFPGSNLVSNMRHFINYVRVRVPETAPELKRDPLASTSSDALDSLQNSGTAQVFSLVAERRKKFQEIINRSNSEANQVVRPKIPSKWSAPGSSPQLTTAILEIKESILSLLIKLHHKLSGKQNSYYPPWLDDIEVLIQPEIPKYNHGDGITAVERILLKAAVQSRMNKRIIEEICRKVTPPVPPKKITAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTAEPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNAEPKKLPIAEEEQIYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNLWQRPCNKSTQDLIKEVEELQGRPGAFPSETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNEFLFMYSVARTNLELELIHRGGSLCSGGPSTAGKRSCLNQLFHVLALHMRLYTIDSEYNPWKKLTQLVEDMNSQVGNEDQQPEVPILYHDVTSLLLIQILMMPQPLRKEHFTCIVKVLFTLLYTQALAALSVKGTEEDRSAWKHAGALRKDTCDAEKCYEVLLSFVISELSKGKLYYEEGAQECAMVSPIAWSPESMERYIQDFCLPFLRVSSLLQHHLFGEDLPSCQEEEEFSVLASCLGLLPTFYQTDHPFISASCLDWPVAAFDIITQWCFEITSFTERHAEQGKALLIQESRWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICEERYRVLEQQWVSHTFDHINKRWGPHYNGL
Protein: Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1) (P02639)
Organism: Bos taurus (Bovine)
Function: Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes. These changes allow interactions with specific target proteins and modulate their activity. Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca(2+) cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca(2+)-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca(2+) dissociation and myofilament mechanics in order to improve relaxation during diastole.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P23297}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:P23297}. Mitochondrion {ECO:0000250|UniProtKB:P56565}.
Interaction partners:
- Protein S100-B
Sequence:
MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDADAVDKVMKELDENGDGEVDFQEYVVLVAALTVACNNFFWENS
Protein: PPFIA binding protein 1 (H0YGH8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
NEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFF
Protein: Zormin, isoform F (Q9W053)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MERRQALDSSMSSLYSVASSSNPNPRQPHTGHQLQTQQSQQSQQSQLDAFNYSATMSSSSPTPSQAMSTAMSTGTGTGTGTTHTTPPSSSSLRATTIGTVVVRCGPIQLVIALLQSPEKIYIKVVELEPKITALGENLDESLRMQREHDETLRNLQSLPGPMDEFVQKADKLLASKRISSELVNAMADTLNIIWQDILNLLQDRQHLLILCTQFHDKMTQCFRKMDQLELACEETLHPPDVPRVQEFLNRFKQLRIDMLTGVMAALKDGNELLAQLEELEKLETLDTRPEHIKRDATRAVHQVQQWLEALHDRRNSLELAWQTRKIQMEQCLALALLGRELVDLEAALQQARMELNTMYSLGECEHTANEMLTKYREWKQQALLLRDRALKITRAKEKVQSAGHFTEEDACARAYAVLSGCTEHLDLVDQREHWLHQSREFFAKAEHTVSVLEKLELELTSVKLPPHSPESYAMFSKVDRDVRNFTEEPLRLGYGILDEVGRTQPETQGVKRVLDELENRKVYIQGICANSSEDQQKVQRALSEFLNHHNELLAWLRASGQHQLQQSVDMGGNLQQAKQFLLQHHELMQDLEIKGELINLLLESIKVHLESLSPQERYDVDSKAESLHKHWIELKDLVLKRVDYVSLLIDFFELANELSSQLDNLQRQLQQTPDEHKLQFLQATWTGIASTFGELKSRGQRFINLKIVDPYLETKSSAQAVQETLNDFSKRQVDVTSSLENWTTSIAEKREVEYLLEKVMSDNEETVAKSTQVDTQLYPVFTSQSVDSKQLLISTREKLTNVIQDIERAQDEIQQRIQTTLGIQTKDQPSLAKIEQVINNLRMLKAKLDGIKYDYRTLVESVIQFLENIVQLRREIDDYFARQQKEPASGADRSIAEHEKFRDQCMDKFRSLITQSELLIDRVRVLEPPGAREIDTDRILKLLENLRLHFESNSSARMSTLERLEKIEQFRSDLEDIDRSLDSVSQQLHEINNQSVDSLAAAKTTSLAFEYFERTIELLEKRIEKFTESTSQQLFITNPESERYVKDELRKLNEKWQSFKDQVKQKRKSLNQATDFFEVVEKIDAEYREISYFYTSVSNKVPYLRDSVEAGNLVNDIENYVTSREAALRSKLDSASQCAHDMNKVSSLYNDVMNIFQSFIKLKMDINVVQERLKQEQRQKEQRERDARDQAEREKAIKEAEAKERLHREEQSRLENQRQQAAIEQAQRELAARELALREQAVREEEARLQAIREQATREQLAREQAAREEELRIQSLRDIARREEEVRLQNIRDEETRIRREEEERIRRENESRSKREEEARIQREEITRLQTLRDQVDQQRIVTENIRKDIQVNSIFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQAERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITTQSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFLVSTSGERQVLTIQKLTHDAVGKISCVAENEAGKATCVAFLNIRGSGLPASSDVQTVSQEHNTESSRVTIKKQTFTTTSTSQVNSYEGNAPQTEVHHSSAHIDQSLKQLGQQRPEIVESHHYQELHKSKEMSSPTVQQKSFSFIQSSGANGQSAVAIPDSPTRLRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKSIADCAILEPSPERLQEVVKTIVYETGPVAPASEFKTEGYKYTSSSMTSNYSHNMQSSSSSSHHETKFSSTSAPPPVVTYPSPIPAQRKTPAAEFSDYSSEIDERFRSVSRANESDAEIKGYRVVFPPTPTPRTNIATNGHKSPVVVITPSPMEFEPTPQDYARPKFEPISKEIRHEIKTETSSKQSKFMQNQQQNQPVFKPKPVAAKFIAATQQQQQKQPQATSRPTMYYNAVAGAPMHVAKVATETKNVMQMHESTESSQRVVNMQQTKRIIHFDSPQEQRDQQILEPFPYSPATSRTPSRQSHLPPPATPTKFVPGEFRESDYESEIDGARIQPLWSPYGDGMTKGFRRVAPPQGAGRSCSLPRTYERVLSPMEFDRGPEMPSKIHVDINTLRKEQRGGSTVTTQNRTQSLNRNTTMRQQQQQQQQQSMDQIDRAGTLPRYGYSSLQQQAENQGRRMGSTFLQKSHQFVDDVSREIRSSASNGIRPGFKRAPSEGSSQQPQAFRDESRVSQYVPELPNTEPVNAHLSRDELAQRQPLFITPLKDIAVGVGGTARFECIVQAHPQPQVNWTHNGGLLESGSRHCIEYRNGVCRLTLPQAYPDDNGSYACTAINPLGAATTSGNLTVSSTNRGFRY
Protein: H-2 class II histocompatibility antigen, I-E beta chain (P18469)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MVWLPRVPCVAAVILLLTVLSPPVALVRNSRPRFLEYSTSECHFYNGTQRVRFLERYIYNREEYVRFDSDVGEYRAVTELGRPDAEYWNSQPEILEDARATVDTYCRHNYEIFDNFLVPRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLGAGLFIYFRNQKGQSGLQPTGLLS
Protein: Bruno 1, isoform H (Bruno 1, isoform I) (Bruno 1, isoform J) (Bruno 1, isoform K) (M9PDB0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSDKSSSATNSLPNSPIHSNNNNPSLLNNNNNNSNGTSSNNSLNVGNNNSNPSLGGSNSNALVSVGSNGIMSAAGLVNNNNNPCSANRNVVAMVDDDACFRLDTDATVTYGEKEPDPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCFVTFYTRHAALKAQDALHNVKTLNGMYHPIQMKPADSENRNERKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNGQSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQIQANLWNLASNINIPLGQTATSVTTPILPNPPQQPSPVLGADAITPASIQLLQQLQAVGLQHQLLQALTGLGAQQSSSATDTSAVAAAGLLTPMTVQNLAAIAAMTQPSLSNAAAAAAAATSPGSAQLTNTAALLWSDPNPMASAYMSTAAGLPQFGSASALSTSPLASVALSAAAAAAAGKQIEGPEGCNLFIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKKPKDSKPY
Protein: Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (P82198)
Organism: Mus musculus (Mouse)
Function: Plays a role in cell adhesion. May play a role in cell-collagen interactions (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q15582}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q15582}. Note=May be associated both with microfibrils and with the cell surface. {ECO:0000250|UniProtKB:Q15582}.
Interaction partners:
- Fibronectin
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Integrin beta-3
Sequence:
MALLMRLLTLALALSVGPAGTLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNKKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETMGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWSSLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTVLEGDGQFTLLAPTNEAFEKIPAETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGMSMETLGGTTLEVGCSGDKLTINGKAVISNKDILATNGVIHFIDELLIPDSAKTLLELAGESDVSTAIDILKQAGLDTHLSGKEQLTFLAPLNSVFKDGVPRIDAQMKTLLLNHMVKEQLASKYLYSGQTLDTLGGKKLRVFVYRNSLCIENSCIAAHDKRGRFGTLFTMDRMLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLMEILNREGVYTVFAPTNEAFQAMPPEELNKLLANAKELTNILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSSKNNVVSVNKEPVAETDIMATNGVVYAINTVLQPPANRPQERGDELADSALEIFKQASAYSRAAQRSVRLAPVYQRLLERMKH
Protein: Protein SUPPRESSOR OF QUENCHING 1, chloroplastic (EC 3.1.3.-) (Q8VZ10)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required to maintain light harvesting efficiency, especially during nonphotochemical quenching (NPQ) recovery, via the regulation of chlorophyll excited-state lifetime probably by preventing the formation of a slowly reversible form of antenna quenching.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:23818601}; Single-pass membrane protein {ECO:0000255}. Note=Mostly localized in thylakoid grana margins, and, to a lower extent, in grana and stroma lamellae. {ECO:0000269|PubMed:23818601}.
Interaction partners:
- Photosystem II 22 kDa protein, chloroplastic
- Thiol-disulfide oxidoreductase LTO1
- Cytochrome c-type biogenesis ccda-like chloroplastic protein
- Thioredoxin-like protein HCF164, chloroplastic
- Serine/threonine-protein kinase STN7, chloroplastic
- NAD
- Thioredoxin family protein
- Chloroplastic lipocalin
- Protein PROTON GRADIENT REGULATION 5
- Ycf20-like protein
Sequence:
MALKLTSPPSVFSQSRRLSSSSLIPIRSKSTFTGFRSRTGVYLSKTTALQSSTKLSVAAESPAATIATDDWGKVSAVLFDMDGVLCNSEDLSRRAAVDVFTEMGVEVTVDDFVPFMGTGEAKFLGGVASVKEVKGFDPDAAKERFFEIYLDKYAKPESGIGFPGALELVTECKNKGLKVAVASSADRIKVDANLKAAGLSLTMFDAIVSADAFENLKPAPDIFLAAAKILGVPTSECVVIEDALAGVQAAQAANMRCIAVKTTLSEAILKDAGPSMIRDDIGNISINDILTGGSDSTRNSTAMLEENTVSDKTSANGFQGSRRDILRYGSLGIALSCVYFAATNWKAMQYASPKALWNALVGAKSPSFTQNQGEGRVQQFVDYIADLESKQTATTVPEFPSKLDWLNTAPLQFRRDLKGKVVILDFWTYCCINCMHVLPDLEFLEKKYKDMPFTVVGVHSAKFDNEKDLDAIRNAVLRYDISHPVVNDGDMYMWRELGINSWPTFAVVSPNGKVIAQIAGEGHRKDLDDVVAAALTYYGGKNVLDSTPLPTRLEKDNDPRLATSPLKFPGKLAIDTLNNRLFISDSNHNRIIVTDLEGNFIVQIGSSGEEGFQDGSFEDAAFNRPQGLAYNAKKNLLYVADTENHALREIDFVNERVQTLAGNGTKGSDYQGGRKGTKQLLNSPWDVCFEPVNEKVYIAMAGQHQIWEYSVLDGITRVFSGNGYERNLNGSTPQTTSFAQPSGISLGPDLKEAYIADSESSSIRALDLQTGGSRLLAGGDPYFSENLFKFGDNDGVGAEVLLQHPLGVLCANDGQIYLTDSYNHKIKKLDPVTKRVVTLAGTGKAGFKDGKVKGAQLSEPAGLAITENGRLFVADTNNSLIRYIDLNKGEDSEILTLELKGVQPPTPKAKSLKRLRKRASADTKIVKVDSVTSREGDLNLKISLPDGYHFSKEARSKFVVDVEPENAVAIDPTEGTLSPEGSTMLHFIQSSTSASVGKISCKVYYCKEDEVCLYQSVQFEVPFKVESELSASPTITFTVTPRAPDAGGLQLQGTR