wanglab/gogpt-training-data huggingface dataset:
Protein: Wide awake (X4YX01)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- F box and leucine-rich-repeat gene 4
- Gamma-aminobutyric acid receptor subunit beta
Sequence:
MEQDAAAGPAKKSGTTLSVDRAAFLLLRVRKVFKKKRQQRKERQAQQSAAAAASGAGGAGGAGGGGGGSGSQSRPGSRKLPPPLLRSRTLPAIIVPGLPVVSLHTDKQTFQLDERLLGSKSRSGSASGHRWSLLTRATNSSSMCSNNNPASSSSSSSNNNNNLHMANNNNTLMVKSLNLPKDDSNLVYRRKSSGSTPHQHQNAHHHHQQHHHLQQQQQQQQQHQQQQLQQQQMLQHLGDSSLFQLSDDFECHADGSLLLRIPAPHVVAARAYRLAARKRAAASSEASTPMTREHTLHEMPLAESACSGSATGSGTTFTRLAKLLHQSSTLAGRSNLQPPPMADNAVQSLGRGLGLGLGEEAPRRLSWERRKDSSALQRSASIDSFAEIVFSESPRPSLAVTGPGACASASGGPSPFSKRPSASSLYSTSTSSSFASQMQAQLNVNYGDSALGSGSATGGPGSGHHHGASGGGNGGSSASSSRRESMLSPSSTRRSKLTRIINALFSAVEHGHLEKARTILESTDVDVNSINNDGLSALDLAVLSNNRSMTRMLLQHGAVEGSQFSVDTIGTKLNGLLKDAESRIHDLSGPEGLCPPVFASRPSISSIIIGNSSASVTGCTGSEVEKQIGIWERRVKGLRRLQLGWDQARPPDAPASVVVDVTGDNSISVQILEPFEGAIGTKFKVQWSTRADFNNVVGESELLEWISFHGTMGAQCHISGLTQGRRYFLRAACGNVKGWGTYRTSVPASVVPSTWRDLDNREDRFVGRHRILDNLFTAVRLARPADVSELTLDPASAQRRNPKKKTTIKQLFSVTTKFQKTLRRGIYFSCIIHCDDKVLVTSEDFPPVIEVDESYPSALHMDYYWLMKVACTWEDVKSLRSDMERNLTSAVHFRTKLLSAVCQMQSALGITDLGQLYYKPLRDAQGTVVLTCVQSVKSQKAVSILNSRWVPVSKLQKKLGALHEDYTINELLISSIGDQLHYQQAALQRLEPGLYLGYLKMQCSIDQIQVVVPVKTPNVLPHCKVRENSHITAEEWQVLHRYSSDPLRLPLDFSAQGGDGASGATATTEVQRLFLYDLTNAMHKLFASMNIKIADATTHRLYDVEVIEHSPDISFLVVCPSAESSCAVPGQSELLLQRDDLASLSIQAFEMIHLRTYQPAIIQKYARLSCILELDTALATHSLREAFSSSELQAAKERLATLQELSASLTIVWKSVRWLMDVVAYARNKNAQPSLAMREILDFAQQRQDEAVATSAGGSANKQLLQLPIRESKFSKTGQGRGSWPGPGTSEDQSQNKPEHSKSEQNLELSAITPVEPASNQVPTQQQQPQQQSQQQQLLQVSNISEYAGSICSEVSFRKNSGDSMSSTYTSRSFYSAVDSASDGNSTNSVFAIPPSRSDDTLADALRHSQAVAAQRKRTSSNIASHTNPLITVHSSSSAPYLAGSSVSLRSGNGAFATDLEHKPLKPATKAASSANLREGGPYLKSTLAELRAVGGEEPVASTSKASSMKSLSRQSSEEDSASCSSLNAEQTSGIIQVYTAYSTGLASGTSLKIHVTPKTTAREVINLVVKQLNMAVVLKGNNGPIYGPEMLENFCLVAVIGARERCLRDDFKPLQLQNPWKKGRLYVRKKHELLAAIEHSNRKSHLI
Protein: Ecdysone-induced protein 93F, isoform C (A0A0B4KHV1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00320}.
Interaction partners:
Sequence:
MHISSYEISLERVAEECMGRRQWKHYQDKLTCSHLNIEEQQPIAIAGSEDEPSQYNHSSKEISQSNPNHCKTENHRLEQQHNGSQLLEEEDSENNQTSHDSSRTPTPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLVAESAATATSSSTSNSHIHQHDSDSNSSASLPHHISSSSSSNNNSSGNRARHIAAASARATPAAATPANSLELYKLLTQRAAKMTSMDSMAAQLAQFSLLADFNLINSLASQQQQQQQQQIASAVTPTTSEVSAAAISPALKDTPSPSVDAPLDLSSKPSPNSSISGDVKSVRACATPTPSGRRAYSEEDLSRALQDVVANKLDARKSASQHHEQRSILDNRLFKMKHHDQEQDHDGDELEDSNDDAEAEVDSNASTPVYPAEFARAQLRKLSHLSEHNGSDLGEDVDRGSPKMGRHPACGNASANQGAPPSIPLDANVLLHTLMLAAGIGAMPKLDETQTVGDFIKGLLVANSGGIMNEGLLNLLSASQENSNGNASLLLQQQQHQQHHQQHHQQQQQQQHVAAYRHRLPKSETPETNSSLDPNDASEDPILKIPSFKVSGPASSSSLSPGGLVGGHHHPLNNNNSLSISNNSNHSSNSHRNGSNRSPHSASPMLAAAVAQGGYSAGNSLLTSSSSSIQKMMASNIQRQINEQSGQESLRNGNVSDCSSNNGGSSSLGYKKPSISVAKIIGGTDTSRFGASPNLLSQQHHSAHHLTHQQQQQQLSAQEALGKGTRPKRGKYRNYDRDSLVEAVKAVQRGEMSVHRAGSYYGVPHSTLEYKVKERHLMRPRKREPKPQPDLVGLTGPANKLQLDKLKAGPHGGSKLSNALKNQNNQAAAAAAAAAAAAAAATPNGLKLPLFEAGPQALSFQPNMFWPQTNATNAYGLDFNRITEAMRNPQASNHHGLMKSAQDMVENVYDGIIRKTLQASEGNGSAAGNGSNGSNGNGHGHGHGHGHALLDQLLVKKTPLPFTNHRNNDYAATCSSASGESVKRSGSPMGNYADIKRERLSADSGGSSDEEHSASHINNNNSDLAHNKNKSGGGGGGGGNGQTNGNGRSSRMTSRDDSETDASSLKSGESGGQQNHKMMDLNGGSSSSSHIKCESEAATGHHSPGHHTTSILHEKLAQIKAEQVDQADQLXEQPMAANPAFAWPPLAAHYYSF
Protein: Plastoglobule-localized metallopeptidase 48, chloroplastic (EC 3.4.24.-) (Q9LSC4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Metalloendopeptidase with a Zn-dependent proteolytic activity and substrate cleavage upstream of hydrophobic residues. Positive regulator of senescence, probably by degrading CCD4, thus participating in the controlled removal of carotenoids from the thylakoid membrane during the senescence process.
Subcellular location: Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:27895226}. Plastid, chloroplast membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAVSVSAPVLSLCYNQSGELSRSLGYRLPKKVGFSSGRRSVSYIGFGAEKVGRFRVRVPICRAVPPLLFKDLDADDFRHPFDKQNTLLLRAIPGLNEFGKALLGSMTEQIMLLENIGTSVLVSKNQLSDLHGLLVEAAEILNIEAPDLYVRQSPVPNAYTLAISGKKPFIVVHTSLIELLTSAELQAVLAHELGHLKCDHGVWLTFANILTLGAYTVPAFGQMIARTLEEQLLRWLRSAELTCDRAALLVAQDPKVVVSVLMKLAGGCPSIADQLNVDAFLEQARSYDKASSSPLGWYIRNAQTSQLSHPLPVLRAREIDEWSRSLEYKSLLKRANRKSTVQKV
Protein: RRM domain-containing protein (Q385E5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRPRLYHYYGAGQLPSHQQVGMAAPEGPPLPHGPPCPGHCQEYSRHMPPTPSREHRPPLRRTIFITNLPLTIDNGLRLLPYVPGEGLIELRVKRSGGRDVGFAEYETGDFALRALRWFQKVAVTAQIAYDCSKVSSSTWAPTQSRFRYPVPYEEYNCCEADPVRSTELLLNSVILIAEWSLSSPACRPKYLSPPPSVHPPNYLVAPHSTSGNTDPAAALHLVPTGTVGWQPQLGPPPPGSRGAGPPTGKSNHSTVPRAPVYTHHHLSQCYGVPSTHCGGAGGNLECLFSAAEAARGGVSQIPSHRVHEVPLPSRGDWERGTPPYDVRATLQDEKLMPGSSSGLVATPTLIKDELLPSSTLFVRVTGARGGSSSGNDSQPCGTSSGPPHCLSPTTSLGPPSPSLTGRGGRLSAYARQCDERREPHPLELLYEWWSQFHHRHRASPQPAYPPEPSSPESPNNQVGSTATSPDEEVATASTTATTVSTSASRVPDGDNAETLMSMILSQDFYSERFAGFRSYVGFSRWSAFVRFDRPVDALQCLRWLRQQPVLRKFVSVQFAREDTRQARPPQGKKEVRCC
Protein: Growth/differentiation factor 9 (GDF-9) (Q07105)
Organism: Mus musculus (Mouse)
Function: Required for ovarian folliculogenesis.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Bone morphogenetic protein receptor type-2
- Activin receptor type-1B
- Bone morphogenetic protein 15
- Bone morphogenetic protein receptor type-1B
- Homeobox protein NOBOX
- Zona pellucida sperm-binding protein 1
- Zona pellucida sperm-binding protein 2
- Factor in the germline alpha
- Muellerian-inhibiting factor
- Follicle-stimulating hormone receptor
Sequence:
MALPSNFLLGVCCFAWLCFLSSLSSQASTEESQSGASENVESEADPWSLLLPVDGTDRSGLLPPLFKVLSDRRGETPKLQPDSRALYYMKKLYKTYATKEGVPKPSRSHLYNTVRLFSPCAQQEQAPSNQVTGPLPMVDLLFNLDRVTAMEHLLKSVLLYTLNNSASSSSTVTCMCDLVVKEAMSSGRAPPRAPYSFTLKKHRWIEIDVTSLLQPLVTSSERSIHLSVNFTCTKDQVPEDGVFSMPLSVPPSLILYLNDTSTQAYHSWQSLQSTWRPLQHPGQAGVAARPVKEEAIEVERSPRRRRGQKAIRSEAKGPLLTASFNLSEYFKQFLFPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVRHRYGSPVHTMVQNIIYEKLDPSVPRPSCVPGKYSPLSVLTIEPDGSIAYKEYEDMIATRCTCR
Protein: Cartilage acidic protein 1 (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC) (Q9NQ79)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17074475}.
Interaction partners:
- Microtubule-associated protein RP/EB family member 2
Sequence:
MAPSADPGMSRMLPFLLLLWFLPITEGSQRAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDHDGDFEIVVAGYNGPNLVLKYDRAQKRLVNIAVDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDEVNVARGVASLFAGRSVACVDRKGSGRYSIYIANYAYGNVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTGGRGVSVGPILSSSASDIFCDNENGPNFLFHNRGDGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSTHGKVRFRDIASPKFSMPSPVRTVITADFDNDQELEIFFNNIAYRSSSANRLFRVIRREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFNNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGKDEASSVEVTWPDGKMVSRNVASGEMNSVLEILYPRDEDTLQDPAPLECGQGFSQQENGHCMDTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKKCSRGYEPNEDGTACVGTLGQSPGPRPTTPTAAAATAAAAAAAGAATAAPVLVDGDLNLGSVVKESCEPSC
Protein: Pre-mRNA-splicing factor cwf19 (Complexed with cdc5 protein 19) (Q09909)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Pre-mRNA-processing factor 17
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-splicing factor cwf2
- Pre-mRNA-splicing factor spp42
- U2 small nuclear ribonucleoprotein A'
- Pre-mRNA-splicing factor cwf3
- Pre-mRNA-splicing factor prp5
- Pre-mRNA-processing protein 45
Sequence:
MEKEKLTNRTSTHKFNETDRETNHSRRHRHHHSRHRESKHGRHDRSERPSSREAGDRSRHERFSKEPLEVKKLPVENEYFDSKFASASSMPSSKDNPQNNDFTNSLQGLDFGTFGSRIQREPIDRKSNKPGEIFVGATLQNESSTSTEHKDIEQLETEINESGINYKIGDNGSRWRMMKLKRVFDMAQDQRRPVEEVALERYGSLKEFDFALEERDELELRKRTRKVQKEVPTGELYEKRCADEFKTRKDSGNGATYYKVIPDPSVNKDTPTESDLNRLKADLLRAQLKKDPNYESLEREYQKACDDFENSLHPSENSNSQATIPSKKRNFDDPTIDEMVQEEKLLNKQRKYGQNYEYAKQIAKDKTYSNNLDYLDENAGKLSNRMKRGDVSLAQISSGGDLKKINHVLDTCPLCLNYETQPLAPVISLSHRAYVSLPTQPELAKYHCLIVPTGHRINTLSCDEDEWDEIRNFMKCIALMFDSMNLGVIFYENAPSPQRYMHTAIECIPVSKRILSLAPAYFREALSTSDEEWSQHRKIIDTLEGSKKYGKWAFRKMMVKELGYFHVWFSIDGGYGHVVEDEKAWGRHDQVPRQVFASMLNLPPEVIRRKGSWTGKKDPREDMFRSRFEKFDWTKGLID
Protein: Heme chaperone HemW (Oxygen-independent coproporphyrinogen-III oxidase-like protein sll1917) (P73245)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently (By similarity). Binds 1 [2Fe-2S] cluster. Although this protein has sequence motifs typically found in proteins binding the [4Fe-4S]-AdoMet radical-SAM cluster and S-adenosylmethionine, spectroscopic evidence suggests that a [2Fe-2S] cluster is present; S-adenosylmethionine was not detected. Has no detectable coproporphyrinogen-III oxidase activity.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9CGF7}.
Interaction partners:
- Oxygen-dependent coproporphyrinogen-III oxidase
- Heme oxygenase 2
- Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2
- Protoporphyrinogen IX oxidase
- Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
- Uncharacterized HTH-type transcriptional regulator sll1512
- Probable nicotinate-nucleotide adenylyltransferase
- Elongation factor 4
- Uroporphyrinogen decarboxylase
- Delta-aminolevulinic acid dehydratase
Sequence:
MNTGTYLMPTAAYIHIPFCRQRCFYCDFPIAVTGFQSLTLDGWVGEYVEAVCREIAGQQHQGQPLQTVFFGGGTPSLLPITGLEKILLAVDQYLGIAPDAEISIEIDPGTFDQVQLQGYKNLGINRFSLGVQAFQDNLLALCGRHHRRRDIDQALTAIAKENIENWSLDLITGLPEQTAADWHSSLTLALAAGPKHISCYDLVLEPQTVFDKWEQRGKLAVPPPERSADFYRHGQEVLTQAGFHHYEISNYGRPGHQCRHNQIYWRNLPYYGLGMGATSYIDGKRFGRPRTRNGYYQWLESWLNQGCPIPGERVSPLENLLESLMLGLRLTAGVTWAQLPSVNQTEKAKILATLTSFGDRRWLEFYGEDNQMLAPNQTTTETVQRFCFTDPEGILYSNQILSALFAALEEDF
Protein: Ankyrin 2 (A0A5F9ZH10)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MNGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGRASPCLERDNSSFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKKDNNE
Protein: Melibiose operon regulatory protein (P0ACH8)
Organism: Escherichia coli (strain K12)
Function: Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site.
Interaction partners:
- Arabinose operon regulatory protein
- HTH-type transcriptional activator RhaR
- HTH-type transcriptional activator RhaS
- Melibiose permease
- Alpha-galactosidase
- Uncharacterized HTH-type transcriptional regulator YpdC
- DNA-binding transcriptional dual regulator CRP
- RCS-specific HTH-type transcriptional activator RclR
- DNA-directed RNA polymerase subunit alpha
- Multiple antibiotic resistance protein MarA
Sequence:
MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWHGQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAIFNLPMHLFLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLMLKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTFGKYVGMSPQQYRKLSQQRRQTFPG
Protein: Carbonic anhydrase (EC 4.2.1.1) (A0A1D5NTS2)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Regulator of G protein signaling 14.
- Ig-like domain-containing protein.
Sequence:
MAQSVWGYDKENGPEHWHQNYPMAKGDKQSPIEINSKDVRHDTSLSPWHASYDPGAAKTILNNGRTCRVVFDDTFDRSVLRGGPLTGAYRLRQLHLHWGSADDHGSEHVIDGVKYAAELHLVHWNPKHGNFAGALKQPDGVAVVGVFLKVGKTPKPEMKRILEEIDNIKTKGKEAPFQHFDPSILFPKSRDYWTYHGSFTTPPCEECITWILLREPIEVSPDQMARLRSLSKNGENEPMCPLVDNWRPLQPVKGRIVRASFK
Protein: ATP-NADH kinase YEF1 (EC 2.7.1.86) (P32622)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: ATP-NADH kinase with a low phosphorylation activity of both NADH and NAD(+) to produce NADP and NADPH by using ATP. UTR1 is responsible for essentially all of the NAD/NADH kinase activity resident in the cytoplasm, whereas POS5 is responsible for all mitochondrial NAD/NADH kinase activity and consequent mitochondrial genome maintenance. YEF1 can substitute for UTR1 when overexpressed.
Interaction partners:
- NAD
- NADH kinase POS5, mitochondrial
Sequence:
MKTDRLLINASPETCTKGDAEMDTMDTIDRMTSVKVLAEGKVLSNFEEPGLMRCGYHDAKNWVRRLSSETIVGEDTSNLYPFYVDTAYDVRRLRKDLINAKVDLQVENLIIICNINDISTVFLMREVVEWILRNFHSITVYVQDIFKKSTQFAVGDLCKDSNCSKNRVKYWSKEFVKKHDSFFDLMITLGGDGTVLFASSIFTKDVPPIVPFALGSLGFLTNFEFQNFKETLKHILTDEVRINLRMRLQCKLYRRNKPEIDAATGRKICYIDFISEHHVLNEVTIDRGPAPCLSLLELYGNDSLMTKVQGDGLIVATPTGSTAYSLSAGGSLISPSVNAIAVTPICPHTLSFRPIILPDSMELKVRVDMNSRGTSWVNFDGKDRVELKQGDYVVITASPYSVPTIESSASEFFESISKNLNWNDREEQKPFAHILSPKNQEKYRLDSSKNGNDTISNPLESSCISSDAQDEERKSVTETETEIVVERTRQAHFAI
Protein: At5g54100 (SPFH/Band 7/PHB domain-containing membrane-associated protein family) (Similarity to stomatin like protein) (Q9LVW0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Expressed protein
- Prohibitin-4, mitochondrial
- Prohibitin-3, mitochondrial
- Prohibitin-5, mitochondrial
- AAA-ATPase At2g18193
- Prohibitin-2, mitochondrial
- Prohibitin-7, mitochondrial
- Prohibitin-1, mitochondrial
- At5g09570
- At2g41380
Sequence:
MNQLALSRSGYTAAVRFLPMLSAAVPKILSSLAAASTVRNFSSTGSPLTSYQINKPSPSKSFTSRLLHQSSSAGTPPQQLFGARSFSSPSSDFNSYHINPPSNWGIRIVPERKACVIERFGKFHTTLPAGIHFLVPFVDRIAYVHSLKEEAIPIGNQTAITKDNVSIHIDGVLYVKIVDPKLASYGVENPIYAVMQLAQTTMRSELGKITLDKTFEERDTLNEKIVEAINVAAKDWGLQCLRYEIRDIMPPNGVRVAMEMQAEAERKKRAQILESEGERQAHINRADGKKSSVILESEAAMMDQVNRAQGEAEAILARAQATAKGLAMVSQSLKEAGGEEAASLRVAEQYIQAFGKIAKEGTTMLLPSNVDNPASMIAQALGMYKGLSTKVPTVVSGKLLE
Protein: Phosphoenolpyruvate/phosphate translocator 2, chloroplastic (AtPPT2) (Q8H0T6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Phosphoenolpyruvate/phosphate translocator that transports phosphoenolpyruvate (PEP), 2-phosphoglycerate and 3-phosphoglycerate.
Subcellular location: Plastid, chloroplast membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Beta-hexosaminidase 3
- Sodium/proton antiporter 2
- Dicarboxylate transporter 2.1, chloroplastic
- Sodium/pyruvate cotransporter BASS2, chloroplastic
- Peroxidase 41
Sequence:
MFALTFLNPNPRLPSPLFLAKSTPESALSRRSRAFSSSNSYPWRPNLRFNGFKLKSATVPENVEGGDLESGSLVKGLKLGGMFGVWYLLNIYYNIFNKQVLRVYPYPATVTAFQLGCGTLMIAIMWLLKLHPRPKFSPSQFTVIVQLAVAHTLGNLLTNVSLGRVNVSFTHTIKAMEPFFTVLLSVLLLGEWPSLWIVCSLLPIVAGVSLASFTEASFNWIGFCSAMASNVTNQSRNVLSKKFMVGKDALDNINLFSIITIISFILLVPLAILIDGFKVTPSHLQVATSQGLSVKEFCIMSLLAGVCLHSYQQVSYMILEMVSPVTHSVGNCVKRVVVITSSILFFKTPVSPLNSIGTATALAGVYLYSRAKRVQVKPNPKMS
Protein: Nephrocystin-4 (Q57ZA4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGMRRSRSAEQTARALLSSAVRYDTWECNTAAEGATDGVLTLQVNWDPLPSEPPFQDVVALRMTLFDVATSHFVGATYDVPRGDEREPVLFQGRPNDVVLAVEILIPAPLPDAVLRRQALFWGYVELSAMASSTSVKLYRGSAHVLTLGRKAWPASEGEEHTITFSAVIIEDDTTRQLLTRLVPTGVMVPRSFVDDCPQASTDIFRCVLQNIYIVPTADDDEWRDSSAEWRIAVVAHNGYRQLGQGAEVSLVFRDGSKPSNVSEFSDSLSLSLSSLPVKSEQIELKEQLLHSATPLEIDGLPVHSATSLVLAIRRKREIDDDFRVLGFCVFPLCVMPMKDCDVRIENLPTLQGPFSCRDQRMLMLEPTSPYGKLPVVVTLVVGYYDTGVVDTVADVSRPGVRGEGRLGRRRGRLGDEGDGVSAAEGEGKTTLLSITEGAKLIPTPFDMRRRQMEILSTADALAPVAAADKRHSAASFPLLDYADDGGAVGAVLEGRSTDVFKMLCNIMEETRRLRQMQEQASRQHRQRAVEAKRVSESGKQLDDATDSITVLNFTPTAVSISWETRRKLEEGLQPILHPLHAVPIDEHTSASCTNAGSMYGIRFEGLTVDESIPIPKDICFMFSFGSLPFQTIGPIRAVALDKSLHVSTFKLYEGKQRGGMIWYEPFEVANNPFLHKHKQRDNAILYVHIYNALTMFYVCSANVRLSEFRRPYNAESARIPKDLVVYRDLSFTEIQVPSKVLPVVRDAGSLHVTLFCICTGQPLPKQSENRVVEPLKVSRVVVARKLPHTNLMEAKHHPQQEATRQGLMTTANDAASEQQAVHSGPETGGVTGVPYPGAQPLVGSTTGLKQHGPTAGVDFSTASSVPDNDMHWRRAQYIKQLYANGIQSSKVHLGARPQDADCEFKLRYLEKQRDELKSKKIGEALMERLTVHHYISVASFRPEQVSVTFQNPFAQGLQFTVEVDPAATDALDVLSCPTVHLGPREHADILFVVRLNQQRNTYAMDSRSASVDVEGEQVNLRAFVYTPTHEAVRIIDVHANVGPPCVDRRYEVYGPSGSRVTKKIFSRFFSSSAFSVSSERDKLLSTMRDACLHVSIASDETTVEPNVVLDPITQSSVTVWEEVTIHTTIPRDCNEQRVEYLTLFEDEKLSKALETWELSIFASQTVTTRELMFGQTTAVALPSEGVEAIYCSDPRMRVEQREGLYMMHLRPHEVGTQHLLLHSLTSNHLAKTLVTVPTVYPTPTYTQTIELSVEEANAPILRRLHFVNVCLSEDIFTVHHNYKYQLHVQPKTFVLAPQDTQVITLHMSMLRLPEGQLEGRWPMWIFINNSADKTVESYLLHVVLRARHVLD
Protein: PITPNM family member 3 (M0RDK4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
- Phosphatidylinositol transfer protein alpha isoform
- Phosphatidylinositol transfer protein beta isoform
Sequence:
MAKAGSAGGPSPGGGAPWHLRNVLSDSVESSDDEFFDAREEVAEGKNAILIGMSQWSSNDLVEQIETMGKLDEHQGEGATACTSSILQEKQRELYRVSLRRQKFPAQGSIEIHEDVEEGCSQRSCKTHVLLLVLHGGNVLDTGSGDPSCKAADIHTFSSVLEKVTRAHFPAALGHILIKFVPCPAICSEAFSLVSNLNPYSHDEGCLSTSQDHVPLAALPLLAISSPQYQDAVATVIERANHIYGEFLKSSDGIGFNGQVCLIGDCVGGLLAFDAICYSAGPSGDSPGSSSRKGSISSTQDTPVVVEEDCNLASSKRLSKSNIDVSSGVEDEDPKRPLTRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDEAEAPAAGTPQLSEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGIDGFQMRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRGSPPLLDAPASPPQAPRSQRPERRLSEGSSHSDSSESSDSLAPMGASRITAKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESASVKESTGLDPTALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMTEPSSGRWVHLDTEITNNSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKITAAYGSTKDISVYSVLGLPASQIFIVGRPTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLRKRNHLRRTMSVQQPDPPATNPKPERAQSQPESDKDHERPLPALSWARGAPKFESVP
Protein: Nuclear transcription factor Y subunit B-10 (OsNF-YB10) (Transcriptional activator HAP3F) (OsHAP3F) (Q69J40)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Component of the NF-Y/HAP transcription factor complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:26542958}.
Interaction partners:
- Nuclear transcription factor Y subunit C-4
- Nuclear transcription factor Y subunit C-6
- Nuclear transcription factor Y subunit C-2
- Nuclear transcription factor Y subunit
- HAP5 subunit of HAP complex
- HAP5 subunit of HAP complex
- Nuclear transcription factor Y subunit
- Nuclear transcription factor Y subunit
- Os08g0206500 protein
- Nuclear transcription factor Y subunit
Sequence:
MPDSDNESGGPSNAGEYASAREQDRFLPIANVSRIMKRALPANAKISKDAKETVQECVSEFISFITGEASDKCQREKRKTINGDDLLWAMTTLGFEDYIDPLKLYLHKFRELEGEKAIGAAGSGGGGAASSGGSGSGSGSHHHQDASRNNGGYGMYGGGGGMIMMMGQPMYGSPPASSAGYAQPPPPHHHHHQMVMGGKGAYGHGGGGGGGPSPSSGYGRQDRL
Protein: Zinc finger protein MAGPIE (Protein POLLEN SPECIFIC GENE 3) (Protein indeterminate-domain 3) (AtIDD3) (Q9ZWA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that regulates tissue boundaries and asymmetric cell division. Contributes to the sequestration of 'SHORT-ROOT' to the nucleus. Interacts with the SCR and MGP promoters. Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors. Binds DNA via its zinc fingers. Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA. Positively involved in gibberellic acid (GA) signaling.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:24821766}.
Interaction partners:
- Protein SHORT-ROOT
- Scarecrow-like protein 3
- Protein SCARECROW
- WUSCHEL-related homeobox 5
- Putative cyclin-D6-1
- Zinc finger protein AZF3
- Protein LOW PSII ACCUMULATION 1
Sequence:
MTTEDQTISSSGGYVQSSSTTDHVDHHHHDQHESLNPPLVKKKRNLPGNPDPEAEVIALSPKTLMATNRFLCEICGKGFQRDQNLQLHRRGHNLPWKLKQRTSKEVRKRVYVCPEKSCVHHHPTRALGDLTGIKKHFCRKHGEKKWKCEKCAKRYAVQSDWKAHSKTCGTREYRCDCGTIFSRRDSFITHRAFCDALAEETARLNAASHLKSFAATAGSNLNYHYLMGTLIPSPSLPQPPSFPFGPPQPQHHHHHQFPITTNNFDHQDVMKPASTLSLWSGGNINHHQQVTIEDRMAPQPHSPQEDYNWVFGNANNHGELITTSDSLITHDNNINIVQSKENANGATSLSVPSLFSSVDQITQDANAASVAVANMSATALLQKAAQMGATSSTSPTTTITTDQSAYLQSFASKSNQIVEDGGSDRFFASFGSNSVELMSNNNNGLHEIGNPRNGVTVVSGMGELQNYPWKRRRVDIGNAGGGGQTRDFLGVGVQTICHSSSINGWI
Protein: Dermatopontin (Tyrosine-rich acidic matrix protein) (TRAMP) (Q07507)
Organism: Homo sapiens (Human)
Function: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Decorin
- Lumican
- Prolargin
- Cytochrome c oxidase subunit 6C
- E3 ubiquitin-protein ligase CCNB1IP1
- Periostin
- Protein-lysine 6-oxidase
Sequence:
MDLSLLWVLLPLVTMAWGQYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANV
Protein: Defensin-6 (Defensin, alpha 6) (Q01524)
Organism: Homo sapiens (Human)
Function: Host-defense peptide that contributes to intestinal innate immunity and mediates homeostasis at mucosal surfaces by forming higher-order oligomers that capture bacteria and prevent microbial invasion of the epithelium. After binding to bacterial surface proteins, undergoes ordered self-assembly to form fibril-like nanonets that surround and entangle bacteria and thereby prevent bacterial invasion across the epithelial barrier. Entangles and agglutinates Gram-negative bacteria, such as E.coli, S.typhimurium and Y.enterocolitica, and Gram-positive bacteria such as L.monocytogenes, thereby protecting the intestine against invasion by enteric bacterial pathogens. Blocks adhesion of C.albicans to intestinal epithelial cells and thereby suppresses fungal invasion of epithelial cells and biofilm formation. Under reducing conditions and in an acidic environment similar to the intestinal milieu, exhibits inhibitory activity against anaerobic bacteria such as B.adolescentis, L.acidophilus and B.breve, as well as B.longum and S.thermophilus, possibly by leading to alterations in bacterial cell envelope structures. The disulfide-linked oxidized form exhibits negligible antimicrobial activity against Gram-negative and Gram-positive bacteria, as compared to the enteric defensin DEFA5.
Subcellular location: Secreted {ECO:0000269|PubMed:27076903}. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:27076903}. Note=Stored as propeptide in secretory granules of small intestinal Paneth cells and found in the ileum lumen as mature peptide. {ECO:0000269|PubMed:27076903}.
Interaction partners:
- Defensin alpha 5
- Regenerating islet-derived protein 3-alpha
- Beta-defensin 1
- Lithostathine-1-beta
- Defensin beta 4A
- Lithostathine-1-alpha
Sequence:
MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL