wanglab/gogpt-training-data huggingface dataset:
Protein: Erbb2 interacting protein (A0A8I5ZWX2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTTKRSLFVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTVVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNIRTFAADHNYLQQLPPEIGNWKNVTVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYMFPQQPRTEDVMFISDNESFNPALWEEQRKQRAQVAFECDEDKDEREAPPREGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETNEESGRDLKQHEDQQVVNKDKGVKPSESITTKSKLDEREKYMNSVPKTSEPEAETNAGNSPVTTNRKSSGNMKHLVNHDDVFEESEELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDAKDTDSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDTALCSPAKQIPIDSNSKIRQEDENFNSLLQNGVNLNNSPEEKFKINDKKDFKLPEYDLNIEEQLVLIEKDVDSKATSEDSHQLDHINMNLNKLVTNNIFQPEIMERSKMQDIVLGTGFLSIHSKSEAEHIENGNKFLNSESINKVNGLSEDTAQSPGRIEPQNTSPADVGISKSTEDLSPQRSGPAGSVVKSHSITNMETGGLKIYDILSDDGPQPPGATVKVASTMDGKNIVRSKSATLLYDQPLQVFTASSSSSELLSGTKAVFKFDSNHNPEDPDIIRASIVPGPQSIPQLYGPPQYNVQYSGSAAMKDTLWHPKQNPQIDPVSFPPQRLPRSESAENHSYTKHSANMNFSNHNNVRANTAYHLHQRLAPTRHGEMWAVSPNDRLVPAVSRTTVQRQSSVSSTASVNLGDPGPTRRTEGDYLSYRELHSMGRTPVTSGSQRPLSARAFSIDGPSTSRPQSARPSISEIPERTMSVSDFNYSRTSPSKRPNARVGSEHSLLDPPGKSKVPHDWREQVLRHIEAKKLEKHPQTSSPGDCCQDDRFMSGEQNHPLGALSHRDLRDSLMKMPLSNGQMGQPLRPQANYSQTHHPPQASVARHPSREQLIDYLMLKVAHQPPYTHPHCSPRQGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEHGQAVSLLKTFHNAVELIIVREVSS
Protein: DNA replication complex GINS protein SLD5 C-terminal domain-containing protein (D9PTP3)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MKFAEEYALAESNLFQKTVLEFMPAALKKMPVPRGDHDDVMVYAKVTSDDVGNVAIPDWQDLNGEVILEMEPESCHLIPFESVHQLVEDGNIQLM
Protein: Probable aquaporin TIP2-2 (Tonoplast intrinsic protein 2-2) (AtTIP2;2) (Q41975)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:10737809}; Multi-pass membrane protein {ECO:0000269|PubMed:10737809}. Note=Tonoplast.
Interaction partners:
- Probable aquaporin SIP1-2
- Aquaporin SIP1-1
- Protein S-acyltransferase 24
- Probable aquaporin SIP2-1
- NAC domain-containing protein 91
Sequence:
MVKIEIGSVGDSFSVASLKAYLSEFIATLLFVFAGVGSALAFAKLTSDAALDPAGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLGLAVGGNITVITGFFYWIAQCLGSIVACLLLVFVTNGESVPTHGVAAGLGAIEGVVMEIVVTFALVYTVYATAADPKKGSLGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGDFSQIWIYWVGPLVGGALAGLIYGDVFIGSYAPAPTTESYP
Protein: Palustrin-2a (P84278)
Organism: Lithobates palustris (Pickerel frog) (Rana palustris)
Function: Antimicrobial activity against Gram-negative bacterium E.coli.
Subcellular location: Secreted {ECO:0000269|PubMed:11087945}.
Interaction partners:
Sequence:
GFLSTVKNLATNVAGTVLDTIRCKVTGGCRP
Protein: UL-16 binding protein 5 (Retinoic acid early transcript 1G protein) (Q6H3X3)
Organism: Homo sapiens (Human)
Function: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:15240696, ECO:0000269|PubMed:19223974, ECO:0000269|PubMed:20304922}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:20304922}. Endoplasmic reticulum {ECO:0000269|PubMed:19223974, ECO:0000269|PubMed:20304922}. Note=Mainly found intracellularly. {ECO:0000269|PubMed:15240696, ECO:0000269|PubMed:19223974, ECO:0000269|PubMed:20304922}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000269|PubMed:19223974}.
Interaction partners:
- NKG2-D type II integral membrane protein
- Retinoic acid early transcript 1E
- UL16-binding protein 6
- MHC class I polypeptide-related sequence B
Sequence:
MAAAASPAFLLRLPLLLLLSSWCRTGLADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGSKTVTPVSPLGKKLNVTTAWKAQNPVLREVVDILTEQLLDIQLENYIPKEPLTLQARMSCEQKAEGHGSGSWQLSFDGQIFLLFDSENRMWTTVHPGARKMKEKWENDKDMTMSFHYISMGDCTGWLEDFLMGMDSTLEPSAGAPPTMSSGTAQPRATATTLILCCLLIMCLLICSRHSLTQSHGHHPQSLQPPPHPPLLHPTWLLRRVLWSDSYQIAKRPLSGGHVTRVTLPIIGDDSHSLPCPLALYTINNGAARYSEPLQVSIS
Protein: (R)-linalool synthase, chloroplastic (EC 4.2.3.26) (Terpene synthase TPS-Lin) (PgTPS-Lin) (F2XF93)
Organism: Picea glauca (White spruce) (Pinus glauca)
Function: Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens. Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (R)-linalool.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MAFVSIAPLASRCCVHKSFVSSREVKPLCRTIPTLGRCRRGKTVTPSISMCWTATVLDDGVQRRIANHHSNLWDDSFIQSLSTPYGETSYLERADKLIGEVKEIINSISVEDGELITPLNDLIQRLSIVDIIERLGIDRHFKNEIKSALDYVYSYWNEKGIGCGRECVITHLNSTALGLRTLRLHGYPVSSDVLEQFKDQNGQFACSAIQTEGEIKSVLNLFRASLIAFPGEKVMEEAEIFSTIYLKEALLTIPVCSLSREIAYVLEHGWHTNLPRLEARNYIDVFGQDPIYGTPNIKMTQKLLEIAKLEFNIFHSLQQKELKHLSRWWKDSVFSQLAFPRHRHVEYYTLASCIDIDPQHSSFRLGFAKISHLGTVLDDIYDTFGTMDELELFTAAVKRWHPSATKWLPEYMKGVYMMLYETVNEMAREADKSQGRDTLNYARQAWEAYIDSYMKEAKWISSGFLPTFEEYLDNGKVSFGYRIGTLQPILTLGTPFPHHILQEIDFPSSLNDLACSILRLKGDILTYQAERSRGEKSSCISCYMKDNPGSTEEDAVAYINGMVNKSLKELNWEFLRPDSNAPITSKKHAFDILRAFYHLYKHRDGFSVARNEIRNLVKTTVIEPVPL
Protein: Glutamate/aspartate import solute-binding protein (P37902)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate.
Subcellular location: Periplasm {ECO:0000269|PubMed:1091635}.
Interaction partners:
- Glutamate/aspartate import ATP-binding protein GltL
- Glutamate/aspartate import permease protein GltJ
- Glutamate/aspartate import permease protein GltK
- Periplasmic oligopeptide-binding protein OppA
- Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZ
- Glutamine transport ATP-binding protein GlnQ
- Leu/Ile/Val-binding protein
- Glutamine transport system permease protein GlnP
- Dipeptide-binding protein
- ABC transporter arginine-binding protein 1
Sequence:
MQLRKPATAILALALSAGLAQADDAAPAAGSTLDKIAKNGVIVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLLQNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTSGTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKKPDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPPKNLNMNFELSDEMKALFKEPNDKALN
Protein: Uncharacterized protein At1g19010 (Q9C5J5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Phosphoacetylglucosamine mutase
- ADP-glucose phosphorylase
- Thylakoid lumenal P17.1 protein
Sequence:
MTDPEKLTALKKAYAETILNTAKEAAARVMITERKARGYQQELASVRDEALRACLRLKQIYDSKVKEAEMISLQKQQKIEELEAQLGEAEDIVGELRTELRESRYLLEKLANGCQTNLSKEEKAPNEAVSLEVREDSSNHERSVVASVIKPHMSDRDLSINRCSYKENKDPCLYTLPSILSRCREAEVVERNTINGDCADVESLTEARKEEAKENDIELSTTPLSPSEKQCIKFSYKRKHNKDGSNSPEGGGSSSQDDDDDDESRSRRHKTGEKDNAYLDSFTSTEPSRDSRRVAQVARQLLPFSEKKGLQQSQCDDVP
Protein: Probable oxidoreductase (O53622)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable transcriptional regulatory protein
- Probable membrane protein
- Probable transport protein MmpL6
Sequence:
MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT
Protein: F-box/WD repeat-containing protein 15 (L7N1X6)
Organism: Mus musculus (Mouse)
Function: Substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes KAT7 ubiquitination and subsequent degradation in collaboration with MAP2K1 kinase, leading to reduced histone H3K14 acetylation and increased cell proliferation.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:18094359, ECO:0000269|PubMed:23319590}. Endoplasmic reticulum {ECO:0000269|PubMed:18094359}. Nucleus {ECO:0000269|PubMed:23319590}.
Interaction partners:
- Histone acetyltransferase KAT7
Sequence:
MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS
Protein: Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Q8VCF1)
Organism: Mus musculus (Mouse)
Function: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > IDP >> UTP > CDP = GTP = ITP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8K4Y7}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8K4Y7}. Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q8K4Y7}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8K4Y7}. Note=Processed form: Secreted. {ECO:0000250}.
Interaction partners:
- Galectin-3-binding protein
Sequence:
MPIQPFDQREWNEPMHSLRISVGGLPVLASMTKATDPRFRPRWRVILTSFVGAALLWLLYSHHQGPVPGRPPTHNAHNWRLSQQRISHYNDTYPLSPPQRTPGGIRYRIAVIADLDTGSRAQEENTWFSYLKKGYLTLSDSGDRVSVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVIYQIEGTKAVPWVILSDGDGTVEKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVMNENPEWVKVVGHRGSVDHENWVSSYNALRAAAGIRPPGYLIHESACWSDTLQRWFFLPRRASHERYSEKDDERKGSNLLLSAAQDFRDISVRQVGTLIPTHGFSSFKFIPNTDDQIIVALKSEEDNGRIATYVMAFTLDGRFLLPETKIGTVKYEGIEFI
Protein: Glutamine synthetase cytosolic isozyme 1-1 (EC 6.3.1.2) (Glutamate--ammonia ligase GLN1;1) (GLN1;1) (Q56WN1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: High-affinity glutamine synthetase which catalyzes the synthesis of glutamine from ammonium and glutamate. May contribute to the homeostatic control of glutamine synthesis in roots.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16472779}.
Interaction partners:
- Ferredoxin--nitrite reductase, chloroplastic
- Ferredoxin-dependent glutamate synthase 2, chloroplastic
- Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial
- Glutamate synthase 1, chloroplastic
- Glutamate dehydrogenase 2
- Glutamate dehydrogenase 1
- Carbamoyl phosphate synthase arginine-specific large chain, chloroplastic
- Carbamoyl phosphate synthase small chain, chloroplastic
- Glutamate--glyoxylate aminotransferase 1
- Glutamine--fructose-6-phosphate aminotransferase 1
Sequence:
MSLVSDLINLNLSDSTDKIIAEYIWVGGSGMDMRSKARTLPGPVTDPSQLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHAAAKVFSNPDVAAEVPWYGIEQEYTLLQKDVKWPVGWPIGGYPGPQGPYYCGIGADKSFGRDVVDSHYKACLYAGINISGINGEVMPGQWEFQVGPAVGISAADEIWVARYILERITEIAGVVVSFDPKPIPGDWNGAGAHCNYSTKSMREEGGYEIIKKAIDKLGLRHKEHIAAYGEGNERRLTGHHETADINTFLWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYIVTSMIAETTILWNP
Protein: Euchromatic histone lysine methyltransferase 1 (A0A0D9SFX4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLYFSRSHFPRPCGGQVSAGSGLTLLLLLLPALWRGWLEGDGQQAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHK
Protein: Sodium/mannose cotransporter SLC5A10 (Sodium/glucose cotransporter 5) (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10) (Q5SWY8)
Organism: Mus musculus (Mouse)
Function: Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2 (By similarity). Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney (By similarity).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:23451068}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Major facilitator superfamily domain containing 4B5
Sequence:
MAGNSTGDAHVPGSQLSVTDIIVISVYFALNVAVGIWSACRANKNTVSGYFLAGRDMAWWPIGASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRFGGQRIRTYLSVLSLMLSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTIIMVVGAVILAVKAFNQIGGYEQLEAAYAQAIPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMPGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPIGLRGLMIAVMMAALLSSLTSIFNSSSTLFTMDIWRQLRPSAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAIFILGIFWRRANEQGAFWGLMAGLVVGALRLVLEFLYPEPPCGQIDTRPAPLRSLHYLHFAIALFLLTCAVMAAGSLLSPPPQQRQIENLTWWTLAPNWSLGTKTGDGQTPQKRAFWARVCNVNAIFLMCVNIFFYAYFA
Protein: Defective proboscis extension response 6, isoform C (M9PC40)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPIAHPLPLCVAWLLLLVVIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTAPTAAYTHPKWMEPYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSNADVASVRVHVLNGEHPEAMQTGSSGCQYNWLTIVLLLGLVLCYSSQQCSSAVPASLTSSLPLPSQLPLPAAAAATTTATGESASSESVTAARASAATTTTTTATRKRCPAVKSCRQTAGRVLTKRSCHR
Protein: CysO-cysteine peptidase (EC 3.13.1.6) (Metallocarboxypeptidase Mec) (P9WHS1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Protease that hydrolyzes the covalent CysO-cysteine adduct synthesized by CysM to release L-cysteine and regenerate CysO.
Interaction partners:
- Proteasome-associated ATPase
- O-phosphoserine sulfhydrylase
- Sulfur carrier protein CysO
- Glycerol kinase
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS15
- ATP-dependent helicase DinG
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS5
Sequence:
MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPTFYRLDSGEQLKVWRAMEDADEVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDPHRHELRSYRIVDGAVTEEPVNVVEQY
Protein: Transcription factor BIM3 (BES1-interacting Myc-like protein 3) (Basic helix-loop-helix protein 141) (AtbHLH141) (bHLH 141) (Transcription factor EN 127) (bHLH transcription factor bHLH141) (Q9FMB6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Positive brassinosteroid-signaling protein.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein BRASSINAZOLE-RESISTANT 2
- Homeobox-leucine zipper protein ATHB-20
- RING/FYVE/PHD zinc finger superfamily protein
- Transcription factor BEE 2
- Transcription factor BEE 3
- Transcription factor BEE 1
Sequence:
MNSHDIDDQLEADVYSNLPSRNDSSTGRRNRNSCRSKHSETEQRRRSKINERFQSLMDIIPQNQNDQKRDKASFLLEVIEYIHFLQEKVHMYEDSHQMWYQSPTKLIPWRNSHGSVAEENDHPQIVKSFSSNDKVAASSGFLLDTYNSVNPDIDSAVSTKIPEHSPVSAVSSYLRTEPSLQFVQHDFWQPKTSCGTINCFTNELLTSDEKTSASLSTVCSQRVLNTLTEALKSSGVNMSETMISVQLSLRKREDREYSVAAFASEDNGNSIADEEGDSPTETRSFCNDIDHSQKRIRR
Protein: Vacuolar protein sorting-associated protein 24 (O14296)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. The lumenal sequestrated membrane proteins will be targeted into the vacuole after fusion of the endosome with the vacuole.
Subcellular location: Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Vacuolar-sorting protein snf7
- ESCRT-III complex subunit did4
- Vacuolar protein-sorting-associated protein 46
- Vacuolar protein sorting-associated protein 20
- Vacuolar protein-sorting-associated protein 25
- Vacuolar protein sorting-associated protein 28 homolog
- Vacuolar protein-sorting-associated protein 36
- Vacuolar protein sorting-associated protein 27
- Vacuolar protein sorting-associated protein ist1
- Uncharacterized protein C162.06c
Sequence:
MQTVRSYFFGPTPQEQNRKWQSIIRKEQRQLDRQVYHLKAGRKKAEVQLKQLAKQSDITNMRILAKEIARANRHGKRLAESKALLGSLSLQLNDQMAMLKIQGTMQSSTKIMQDVSSLIRLPQLSETMRNLSMELTKAGVLEEMRDEMFLPVEDDEELMDLADEDEEVQEILTKYNVIPAPSEKAADAATHREQSLKQALPSLSNGIAKDSTEIDEEQLLDIRDKLDALKS
Protein: Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A homolog) (Delta-interacting protein A homolog) (Q6PDY0)
Organism: Mus musculus (Mouse)
Function: Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion. Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:15644333, ECO:0000269|PubMed:22666460}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q15834}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q15834}.
Interaction partners:
Sequence:
MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPGGAVGSGAGPTPELALPPCGPRDLGDGSSSTGSVGSPDQLPLACSPDD
Protein: Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (CAP-G2) (hCAP-G2) (Leucine zipper protein 5) (Non-SMC condensin II complex subunit G2) (Q86XI2)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.
Subcellular location: Nucleus {ECO:0000269|PubMed:14532007}.
Interaction partners:
- Condensin-2 complex subunit D3
- Condensin-2 complex subunit H2
- Structural maintenance of chromosomes protein 4
- Structural maintenance of chromosomes protein 2
- Condensin complex subunit 1
- Condensin complex subunit 2
- Condensin complex subunit 3
- Serine/threonine-protein kinase PLK1
- Histone lysine demethylase PHF8
- SHC SH2 domain-binding protein 1
Sequence:
MEKRETFVQAVSKELVGEFLQFVQLDKEASDPFSLNELLDELSRKQKEELWQRLKNLLTDVLLESPVDGWQVVEAQGEDNMETEHGSKMRKSIEIIYAITSVILASVSVINESENYEALLECVIILNGILYALPESERKLQSSIQDLCVTWWEKGLPAKEDTGKTAFVMLLRRSLETKTGADVCRLWRIHQALYCFDYDLEESGEIKDMLLECFININYIKKEEGRRFLSCLFNWNINFIKMIHGTIKNQLQGLQKSLMVYIAEIYFRAWKKASGKILEAIENDCIQDFMFHGIHLPRRSPVHSKVREVLSYFHHQKKVRQGVEEMLYRLYKPILWRGLKARNSEVRSNAALLFVEAFPIRDPNLHAIEMDSEIQKQFEELYSLLEDPYPMVRSTGILGVCKITSKYWEMMPPTILIDLLKKVTGELAFDTSSADVRCSVFKCLPMILDNKLSHPLLEQLLPALRYSLHDNSEKVRVAFVDMLLKIKAVRAAKFWKICPMEHILVRLETDSRPVSRRLVSLIFNSFLPVNQPEEVWCERCVTLVQMNHAAARRFYQYAHEHTACTNIAKLIHVIRHCLNACIQRAVREPPEDEEEEDGREKENVTVLDKTLSVNDVACMAGLLEIIVILWKSIDRSMENNKEAKLYTINKFASVLPEYLKVFKDDRCKIPLFMLMSFMPASAVPPFSCGVISTLRSREEGAVDKSYCTLLDCLCSWGQVGHILELVDNWLPTEHAQAKSNTASKGRVQIHDTRPVKPELALVYIEYLLTHPKNRECLLSAPRKKLNHLLKALETSKADLESLLQTPGGKPRGFSEAAAPRAFGLHCRLSIHLQHKFCSEGKVYLSMLEDTGFWLESKILSFIQDQEEDYLKLHRVIYQQIIQTYLTVCKDVVMVGLGDHQFQMQLLQRSLGIMQTVKGFFYVSLLLDILKEITGSSLIQKTDSDEEVAMLLDTVQKVFQKMLECIARSFRKQPEEGLRLLYSVQRPLHEFITAVQSRHTDTPVHRGVLSTLIAGPVVEISHQLRKVSDVEELTPPEHLSDLPPFSRCLIGIIIKSSNVVRSFLDELKACVASNDIEGIVCLTAAVHIILVINAGKHKSSKVREVAATVHRKLKTFMEITLEEDSIERFLYESSSRTLGELLNS
Protein: Rad, Gem/Kir family member 3, isoform E (Rgk3L) (A0A076NAB7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RE33762p
- alkaline phosphatase
- non-specific serine/threonine protein kinase
Sequence:
MVDDISPMHHRMQKKTRSASICATGASIETVIHGMPGASGSATPEGGTPGYRRRRPATRSQSARITSGARSVRQKTKAQQQQQQQQHTLQETRSYCTSEPRLSETETPPQRRKLSQRRPQTHAHRKSNAFLDVPTMNMHHLRVNDDDEDVDRLRTFSASKGGIINRGDSFRRRRSRSNSLAPSSPMHTRNGVGGLGGVAGGGSSLGLGCGYNGGSSSNGFGNANAQENHQPVEFYRVEMLGSAGVGKQALLSQFRTSDCINAYDGPECDDAEQNVSIILNGTESELKFLTGNPESKDELEQADAFLVVYSCIDKESFTRAKQILSRLQDMDLLRHRPTILVANKIDLARSRAVSAQDGKCVACTFGAKFIEVSVGINHNCDELLAGTLTQIRLKKDQVQLQLNPKKSKDKDKNKFKENTNIETVETDNCLTDLKADDGGPRDANSPAHWYKSRSVMLASMKARQMLTWILGKEDSKFKHCENLQVL
Protein: Uncoordinated 76, isoform D (M9PGS9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MWWTITGNFGNILPIDWSKSYTRQMHMPTLNLGQNHTKQQQQNRNQQQQLHNQSHQAYPHTNGLGSGSGSGLDAQTPGDEFNDLTSEDEAVANDLDMHALILNGLNGDMDDQPIKTVEEVIKEIDDIMDEAESPLDEPETCDSEVIEKAREVLGAPLYAEKLQYLTTTQLNELYMEMEVLIQELSETLINELALRDELEFEKELKNSFISLLLAVQNKRRQYHVEKKRGKFQGPEPKYLTTVIPYHLENGTPNNQSLQVLIKILKAINEDSPTVPALLTDYILKVLCPT
Protein: Jitterbug, isoform M (A0A0B4KEX6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDVKDIKGAKVTHAGLLKHNSDGTTETQKITHAGLVARSPEGTAAKGMNIRGNEDLWVEIQANTFRNWVNEHLRETGMQVHDWATDFCDGTCLCALVENLQTRPLKPSWNRRPANQHHYLENATTALKSIEADHIKLVNIGNVDIVNGNIKLILGLIWSLIVRYQIGRSKFPPRKLMLAWLQAALPDCRITNLTTDWNSGVNLAALLDYCQPGLFPHWRSLDPSQSVRNCTQAMDLAQREFGVPKVLEPEYLASPWLDELSGMTYLSYFMKPGGPGYNATMRWVNTQVKDPVKNFTTDWNDGRVMCEIIKGLGGSAPAPEKLSTDPFHYENNIRKAVDAGARLGVQPILTAKDMANPEVEHLGIMAYAAHLQWVPPRPPLSDLVSVYLESTSGRVGEPTHFRIDVMSRDISLSSVRCHVVPPSGQPGQPVRLNAHGEGVFVPERYGMHEIVVEIGEDSLGGHFFRALPRLLQVAPPGMAPCALGSLVEVLVNATGAPKTEDILVTAVSPTGISHNCPLKKIDEGHSAIFKPDEAGIWEIAITYQGRHIQGGPFTCAVFDASGVSVHGLDGAMPLRAHTFEVDARGVGVSGELHVDIVHDKHSLVCSVEKIVENKYRVTFMPRQNGKYRVYIYFNGYDVKGSPFIMRVGTKGRSGKTRSSPLHDSKHRSESPSMHFVSTTNTRHNDYRNSSLSRHNTAERTNSYSPQYSPKLDTTDYHSSSSRYYKRESETRSSEVHTHSPLTIKTSNQYESSTRNITSSPRHASVSPVQRYSPNSAYITTATHRMGSPLTSPVSKNGYESSRTVEKSSTYKSTSNYVTDSNIRASPSLYGTAERLRRTGSPEPRIDHSSNVRVSSMKPASARRDSWDVINKTKHMLSHNSLESLANMTEKQLNTELQYNRPDLDHETHRNTQYNKFALHKQQQQQSDYRRDSPDDGERYKPSAITVKSHSNNTYTDKSGGYTKTVKESSEHVVTESNGHGPSPGYGYSSLSRFRPIDGNATGARAIRVQDIPNGSIGRPVEFEIDGSRAGSGNLEILVNGGRVTSSVRSLGGQRFIASFTPHEHGTHTVQITFNGETVPGSPWHAEIMSSPGLTALGESTRLVPANTPAVFEILPPPGQSLSKGECVATVLTPSKSKLNARVTHEAANGAARIEFVPTEVGTHVIDASINGTKIAGGPLIAKVYDSSLIQVTEVNGGVVGQACQFRVDASAAGEGQLEISINEGEVPNHVQVVGGGRCLVSFTPEQAKSHLIDIKFNGETVRGCPFVCAVADTSRVLLNLSNLELIPVNRPSSFHITVSGGGAAELAVSVRGPQGELPVRVTGDIHAGFTAEFTPTTVGGHSINVEYNGFAVQGTPFLAKSYDASKVVVGSVSRGTMGRPVQFTVDAGDAGEGNLEITISAKGQNIPTQVHPQGSARFSVSFVPTESCEHTINVSFNKMPVPGCPITVSISGGVAGPQVSLGGPGPVHQTNSFVINHNGGRLEDIEVNVEGPAGQSVPAQVHQSADGVFKAEFVPRVVGEHRVNVTVNGLPTAGSPYAAKVYDVSAIKVKNVSSGTVGKAVTFLVETSQAGPGNLEVTVNGGRVPTSAQAQGQHTYAISFTPREAESHTVELRFNSQDVPGSPFTCRVAAAARIQSPETMDKVSVGRLFEFVVESDTKPTVEVLGPARRSVPVKIDALGSSTLGYNVKFEPMEVGDHSVEVRLPGGGHVEGSPFLLKAYSAEKVIVTDIRAGVVNKSVSFGINASQAGAGNLEIIVAVNGKNVPNFVQSEGNARFKVNFKPTEAATHSLSVRFNGHPVPGSPFSCHIAAAAASPSMGLPRAMAMGECLKQAAVKMDNTFELEGFDGVEPQIFVTSPSGDNEHCQLSQHDGGSYSASFRPTTVGRHLISVTANDQHINGSPFSCNVFDVSRVSISGLEQQYGPANLGVPVTFSVDAAGAGEGTLELVVSTDSSTVKAEVVACARGLYDVTFVPQSTEPHYVNITFNEVAVDGSPFRVDIQQHTQHIQIGSLAAIDFPADDQIVEIFSPDQKSVPYSINRQTAEFRTHMTGNYTLRFIDRETRQHIGSRTLCVFDPTLVKITEVSEAFCHRPASIGVSLNEAGQGDLSALVRCGATEVPHTIRGPSKTGVYEIVYQPTRVAPHKISILFNEVPISLKPLEINVLPASAGKEISVSGLGLYQSRVGKTTSFAIDTVKRPAREFDVVVSGPGGQALPVRCYQTKNGHLQAEFTINKPGQCVIEVLHQSKPLPGSPFTCESFDSSKVSTQGVTKEPLALHSPNSFTVRTDNAGTAELEAFAISPSNQSIPVLISEQSDGVYNVEFVPSQPGNYKLTLMYGGETIPSSPLNFTASSSGVRNDARAAGHGLEVCHRNKEASFVVYCPIAPNVQIERLDEYGERIEPKIKALGNNEWRISYTILSVGKYEIRASCPNRGSLPGSPWHISCVESNKVTPVGGWGTLVDHDGRLILPARIIFDVENAGPGKLVCSIDGIEIPVDKLVDGKMCLNITGENLAAGEHDLDLTWSGLTITQCPRSAFVTGQQAADKVQLMGRGLAAAQAGEAAHFTIDASNAPAGRPEVILTSQDNTSLPVSLAQPRPSENIWLASYTPLKSTTGTLNLSVKWNGRLVKGCPLTVAVGSSMDASKVIVSGEGLRHGIVGKDIKSWIDTRRAGPGELTAHCAGVRKVAYCELYDHGDATFTLNIKPQESGRHILTIKYGGQNVPGSPFALKVAGAPDASKVRVYGPGIEHGVLATFQSRFICDTRGAGAGQLTVRVRGPKGAFRVEMQRESQKDRTILCKYDPTEPGDYRVEVKWAGEFVPGSPFPVMIFDTEEELRRYLQGI