Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q586K5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Endo/exonuclease Mre11
- BRCT domain-containing protein
- DNA repair protein RAD50
- FHA domain-containing protein
- non-specific serine/threonine protein kinase
- Peroxisome targeting signal 1 receptor
- Phosphatidylinositol 3-kinase catalytic subunit, putative
- BRCT domain-containing protein
- Recombination initiation protein NBS1, putative
- Protein kinase, putative
Sequence:
MSASQDASMLGLFRGRHPAVSQRSISLDKEALKRSLTTICNDLQGATIREAPKFLQDLRTFLDNTVEQSCMCVQDLFGQHVANNILFVVMNSVLRPALQQYNEAVTKRRQMAALGRVNIAEDESGTSAYSENRGRKLRTDFARPWRALIETVHHNLPASVVQQQQQTAAHSSSSSFSSMLIGTGSSSVGGGGGDTHSMSSGFDTAKHHHGGDGRDNFTSSSFKSAPQHVAPVGGGEGWGEASHHIWAVPPNHAVLPLLWKNAVPLNGFVSCALEVLQSEVLAPVCGQEFAQLLLHLFLFDGYLSNLLPKLIAKLTVRLLDLIDKTVYEANGSDTGGGTGTWVRGRGAPPAGGCGNSKKSNRGPTSHEMNDDGDQAPSVEEGTTYAAVLVQLFRAPHLLSAFMPSQDTAVAVDKPENNRKVTLPFVMQQLVNITMRRHQRPTCALRLEEHLLVAVNLLIKIARDDYPLTSGVPLDLLKPLCHFFYATTRRDGWRLEALTLLTTQVCASFSAVLGQNVRADIERNRPRAAHHHGNVLGSNSCSTTGNASNHKEEKSNAPLLRSQAKSSSASPPPTTSLICSPTAVQAPASPFSASTPPRTLVLLHETVLPFMRQLFTVPRSEFNFVSRRELSHFPCRPLASLFDFGAIVLYLACSTHDAYLALLFTSPGSRSGDGTSRHSGGDSGGKSGDRSESTGSNKSHDNGVSTGRKRPREGDEGIADVSDQVGFSHDPQPVSTVHPSNVILQLFRSLFFLESGRDAAETPVRTCRTLQGSVTGALSDSNLHRCGSASFGLGAGGHTPSSSTSSGGPIGAPAVQNNIKDSSLFMLHLLAQPCATLGFTEHQCTYLVEQGILPIFPYYGVQLESLLLAVLHAVGPRSSVVCQQELFRWLIRRYFPTETAQREEESHPKEQVYSLLSLLLERGVVGQCPFLVTTEERMRLHSAVHFSAITARIYAVVGGGALPSTPSTGFGGPVAMAGGISGSGVEGVLPLNQPLGETFSAARRTGVSAAGSSLLGPSASAAFAPTNNAIKTGIPVSLFKSMMQFLSAYHHYGATAAQITASHRVSMKKRVRDGCSQSLHGDQLMDLPTASLRLSTVLSFVVAGISHGVCFFPHDDGLVWRQETDSPAAVARAAEAFESVLSSAEDHVLSLCLIITESTMGCQHSLVATATSGVKVTTASEAGTDSANFLYNMGGGRSVASLRRIREKLGHSRRLVGSAFTTPEKQLPASVCEAARGHWLLLYEFLSLSREEVLRDMQGPSTTGVCSGYDICGQYPEGTSEGSVLDVGGSRLRPGDTPAAVMEALSAEVVRAVTEMACSAKIATTSAGIVGTEPSAYQQQQGMCEETVALIHRKLCIHSIQVLHFILRLYRLGIWHLPEGKCSRQPGECTGAGVVASAKSDDNANLTGGCSDRLNSGDNGDSESEDLRVLLDFTPQQLFEQPASVFQRLPTAPGRIYYAVMWLCHYLTTRLLRDSLTQARAVLRALLLLLHDVGTELLSRSLALWEPRQTILRFVGATCRRLLNEGISRLASWKQTEITTTDSTIIVQATMRLSCRVLGEFLTLVRHKRLMLAAAEPLVDPSDVTAVIVDILVKNELILPLDRISGRNDAAEEGADTRAILKPHPFVPFVLASVDCLAYLLQLLRGLWGDMNARNALLALLETLFARYAHSMCESIFATFGYYALHTKGTATVAARYAIAPAHSAERCEGQQNEYRLSTTGVGVDEPEKELLCEEGQMLKRFVERVSDSAQSDIPPLTPQRQCAVISAIYGLLFLCDARVAEKLGRYIFSFFSPDAPYAVRQHTALQVRFLFSRFSDRAGAVMRDMIASAREGMNSTSGMSCATSLRAVAEAARAVPLMEPRVVCKLLECWATHGFMHKDLILECLQLIGEYARLRVGGGGVADDVGTLLGSDAAELELAIGEGSKMSAQQLCHHHRERLLFDWLWSFGHPLEALPITCFGFSSISQLWAAFMPLLLPIVLLCCSSRGSNSVQAREAVEDEAAGAVFMRPSSLLWRLAIFHHRQQQREKTPIEGGEKGDEAVGQEPDPECTPQLLIECIVAHFPDVVARLLLFASLSEKSGMGVEWSQLTGARVRCGHQSFMGLKDTRKCVEEPDEDAKLEEAGCAARVALEWLRSALSHRFASLMRYNADGILCRFVDLVGTLSPYIELKQIHWAVKLLCESIGDVASSNTQQAMTEMRELSRGSHPPSAFDHQAVHAFFSNDGGDHAYVLLQRLYVCLTQDLNRGARRLLLVRMFRDIVGEWWSRDLLQQVPHMLHTVLRMCGNMLMTCPDVRPVVCEVLLHVWSVVVTTPATAPSAVCIGAAADEAFISTIMSSLTEESRVVSSTWDAMKRSRRASQGSCADTPVEFINVDNEEEEVAVSKSIGVEQQQDEVRQQDQADMANSSGVSAKGPARRVARVLSQLENVILVSGAPASSFYDDVASAVDRDREAFVALIRLYRLNEQQRLRLSGAGSQRVPNSTENVTIKTASVAYNTCCRAVQHLLTVVCSDTAGQSAQTTVAVGVSPVAVAAPVTVFQTTNRDAQLSAFHLLRAICWCFIESGCESCVESLFSPTADIHSLLQQRSLDEALHHVYRQHLEQLYRLSFDADACNAHIASTTLRGWLTSIKKEDGKSINEGDPFSEGATVKVEALSDANDADEAPVRSRRKVGGSATLIRRTLQLFEKDGEEQRQTRHNRGNQHLEWTNSFVSLGDLAVFCRELSSIPRNISAVRTDGAVEQLNSLRSSLVWDALQLHEDEPRFLRLFLIAIIRQYKLQERLGTISTVLNCMLLPVQITPKGITGGNSSLTWFIEGFLPITLLHVILLKETSVQREERATWSGRLEECLFKRAQQFPHTTRLFLRALNICRSVIMTAVRSRGVRSDASDYNQRGQFALPEGRGAAEVAGGITFPPYVRSEYGDPPEINDMKDSYWLSDIDPLTLAAAAAACHEPHLAVLFTELSGESLLGRRKGIPSTVPDISAASTRGLSADAHKQKETSVLFPSVNPDVCRRGASDGRPRQLRADVAQAELALRLFNFRSAVHAILVDVKEALRLREGNYDDLPASASASSKPTLTSASAVGGTGAASRLAMPAQTGAAAEEHTTPWEEAFLLQHPMRRIEQEKSRGNWQAVLCLLDRLEHPVSNNSSRDYQTSILDARIVIEKANALLHLGDPGTALHLLASALKRKFHTSFFGVVTGSNDHIQQPVQDATEEEERHENECMQLRAALAGALWRSGRWDLRFLQEDGYQQQRKLHDLLLPTTVTVDEGIYHALQCVRRGDRHDAHRWCAQAQQHLLRQLNPSNWRYIMLRAEALQQIEDCGKHEIRVGSARPPRWVGTSLAHVRLPYDELQLLDSVQQQLCVVCKQPQWWLTHLEVCSERALCSNKPLLVRQWVSSYAELSTVVDGGVGGGSVEAHGSNGPDCNLKPVLQAATSSCGLPASVLIALVHARAEFACGYPHRAIAILQNIAAPSPASPQVRASGDPQFSFLSPFAVGVPGLSFPKNPSLMPPVVLQLVAWVTEARLVPLSQIVRDPFFTRCAIDDRTGYCSLQLARLCHTLTRDIAERLRSYNYRTMQKSMESLIHTRTELQQKQEQLSKSGVSREEKNLLRRRISGLIAEHACDEREFVEEAESYALYRRSALNGYSRFLQLSGHDGDDNDILAVFGFVSLWLHQDESYVRKDTSPATDNVISKAISNTPLHKFLPLYSQLVAQLGTSLDNKNLETLVHRVATEQPLRAVWPLLALANGHVFGPGVGDTGGKGASSGGVVHVVDEEKVAIARRILTSLKEPSAQPWGKSKSTGSSKKTSNDAEDASAFECRRKFITDAESLSEAYIQLAFHRADAADNVECNIPKTFMLISDALQDLSIPPPTLTVPATNSALSASLLRHEQDEQRAQVPRVMKYKSTFRTPGGINVPKVLRCVLSDGRTVQQLLKSQDDLRQDSLIQQVFGLSNALFEKHPLTRQLHIYTYNVVPLAPTVGLIEWVDGTIPLDRYLNSSSSKNPTGAHERYFPTEITSKVCRARLNEASKTQKHAVLLSLYAEFSPALHYFFLEHFFTPQEWLQRREAYTRSVAASSMLGYILGLGDRHANNLLLHVGRAELVHIDLGFAFDQGKLLHVPELVPFRLTRNIVDGFGVQGTEGPFRHHCQAALQLLRGQKEFFTTILAACAHDPLSRWAVSIIPPQQQQQQQQNAQQDEQDSNGSGANSARQQGVGVHRKKPTYADAERVLSRVMEKIQGYESGELLSVRTHVQKLLQTAQNTELLAQMFHGWSPWL