wanglab/gogpt-training-data huggingface dataset:
Protein: Fibronectin (FN) (Q28275)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (By similarity). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P11276}. Secreted {ECO:0000250|UniProtKB:P11276}.
Interaction partners:
- Integrin subunit alpha 5
- Integrin beta
- Integrin beta
- Integrin subunit alpha V
- Syndecan
- Syndecan 4.
- Integrin beta
- Integrin subunit alpha 2b
- Integrin subunit alpha 8
- Integrin subunit alpha 3
Sequence:
LGAALRSAGAARGRRQAQQIVQPPGPPGCYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCESKPEPEETCFDKYTGNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHASLQTTSTGSGPFTDVRTAIYQPQPHPQPAPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTPNYDADQKFGFCPHAHEEICTTNEGHDMGHMMRCTCVGNGRGEWTCVAYSQLRDQCIVDDITYNVNDTFHKRHEEGHMLNCTCFGQGRGRWKCDPIDQCQDSETRTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPGTTGPVQVIITETPSQPNSHPIQWNAPEPSHISKYILRWKPKNSPGRWKEATIPGHLNSYTIKGLTPGVVYEGQLISVQHYGHREVTRFDFTTTSTSPPVTSNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEEGEQSLILSTSQTTAPDAPPDPAVDRVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGVPRSDKVPPPRDLQFVEVTDVKITIMWTPPESTVTGYRVDVIPVNLPGEHGQRLPINRNTFAEVTGLSPGVTYHFKVFAVNQGRESRPLTAEQTTKLDAPTNLRFANETDSTVLVIWTPPRARIAGYRLTVGPTRGGHPKQYNVGPSASQYPLRNLQPATEYTVSLVAVKGNQQSPKATGVFTTLQPLSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTISVLRDGQERDTPIVKKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIELTNFLVRYSPVKNEEDVAELSISPSDNVVVLTNLLPGTEYLVSVSSVYEQHESTPLRGRQKTGLDSPSGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHTSGRPREDRVPPSRNSITLTNLNPGTEYVVSIIALNGREESPPLIGQQSSLQPPTSLLISWDAPAVTVRYYRITYGENSPVQEFTVPGSKSTATISGLKPGADYTITVYAVTGRGDSPASSKPVSIDYRTGTDSSMQVTDVQDNSISVRWLPSSSPVTGYRVTTTPKNGPGPSKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQPLVQTAVTTIPAPADLKFTQVTPTSLTAQWTAPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAIPANGQNPIQRTIRPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDRLTFVFFQPLMHHPTCVFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIQVIALKNNQKSEPLIGRKKTGQEALSQTTISWTPFQESSEYIISCHPVGIDEEPLQFRVPGTSASATLTGLTRGATYNIIVEALKDQKRHKVREEVVTVGNSVDQGLNQPTDDSCFDPYTRLSESGFKLSCQCLGFGSGHFRCDSSKWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGAEPGHEGSTGHYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Protein: Down syndrome cell adhesion molecule 1, isoform AK (Q0E9K5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVNQFYEAEIMTEYVIRGNAAVLKCSIPSFVADFVRVESWIDDEGNVLSFSDNYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGSVAPKVDVKDRITWLDKPMGQALSLLCPAQSYPMPVYRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPSIAPFSFGDDPVNTGENAGVQCMVQKGDVPITIKWTLNSRPIINGEEGITILKLSPKTSVLNIAAVEQDHRGVFKCIAENKAGSSFTTSELKVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Tubulin gamma chain (Gamma-tubulin) (P34475)
Organism: Caenorhabditis elegans
Function: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000305}. Cell junction, hemidesmosome {ECO:0000269|PubMed:26586219}. Cell junction, adherens junction {ECO:0000269|PubMed:26586219}.
Interaction partners:
- Gamma-tubulin complex component
- Gamma-tubulin interacting protein 2
- Mitotic spindle organiZing protein
- Spindle assembly abnormal protein 4
- Spindle-defective protein 5
- Zygote defective protein 9
- Pharynx and intestine in excess protein 1
- Probable histone H2B 4
- Meiotic spindle formation protein mei-1
- Spindle-defective protein 2
Sequence:
MSGTGALMTVHVGQCGNQLAQAFWKSMVDEHGINERGQTTHEDDMNDKKDLLFYQADDDHYVPRAVLVDLEPRVINGMMQSPNFSNLFNTDNIFMSDHGGGAGNNWASGYCQGQEVQEKIMDIIIREAENTNNLDGILFTHSVSGGTGSGTGSLLLERLREAFPKKVIQTYSVFANSDTSTDVVVHPYNWVLSMQRLIENPDHVVVLDNAALHRLAAGKFKTDTPTFDHINSLVARIMSTSTAPYRFNSAMCPSIRYLDLAPFPPMHFIQSAISPVVDPNENFTRKTSVADVTRFLLKPTSMMVSTASRVRPNDCMLSAYMFLQGQIEAHTIMTAEQNVDFAIRRPPFYMLKPLRMMHAPLSPYVRPQYKVSGLLLNNSTSVAPLFESLLSKYDKLRSKRAFIDKFEKIDNFSLDMMDDAMHIVQDLLDEYKAVVQKDYLTRGL
Protein: Kinesin-like protein (F1LQZ3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Kinesin-associated protein 3
- Kinesin-like protein
- Beta-arrestin-2
- Beta-arrestin-1
- Protein smoothened
- GLI family zinc finger 3
- Kinesin-like protein KIF3C
- GLI family zinc finger 1
- GLI family zinc finger 2
- Intraflagellar transport 88
Sequence:
MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEVSGSDISGSEEDDNEEGELGEDGEKRKKRRGSSSSSSSDSTCSVIEKPLDEFLPHQAGKKKVSPDKMMEMQAKIDEERKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPQDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKERDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ
Protein: Candida glabrata strain CBS138 chromosome G complete sequence (Q6FST9)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- V-type proton ATPase subunit a
- Vacuolar ATPase assembly integral membrane protein VMA21
- V-type proton ATPase subunit H
- V-type proton ATPase subunit
- Candida glabrata strain CBS138 chromosome J complete sequence
- V-type proton ATPase proteolipid subunit
Sequence:
MMIKQLFVSLFLLFSYAVASNKFFLTFSDSELNTDSLSVAASESNTPLLIIKVLNIDVLRNLFTSLKNEEVGKYTFWRLIEEDIGQVDSYVIDSNYDQVKSEANKYTLEFQENLDNYEKVSEIIQQNILNLETKSQTLPLLALELTSDNKKVRRDRIIDEIEEILEEYDILDFFDDNESDDKNNEGKTPSEESRIWTEGLLMCLIVSGILLIILIISLSWLSDLSISYGALERPNNMAKKTN
Protein: Thyroid hormone receptor interactor 10 (W4VSQ9)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHFEDLGPPPPPSQGPARALSLWPRVKTSVLWKKTKGTAGPGSGGKREARATCPPPTSESRSIEPCQRREEGGCRLLLLGHGEPQDLCTLFLTPWLRLRPV
Protein: Solute carrier family 22 member 14 (Q497L9)
Organism: Mus musculus (Mouse)
Function: Riboflavin transporter localized at the inner mitochondrial membrane of the spermatozoa midpiece, which is required for male fertility. SLC22A14-mediated riboflavin transport is essential for spermatozoa energy generation and motility: riboflavin is the precursor of FMN and FAD, which are coenzymes of many enzymes in the TCA cycle (the citric acid cycle) in mitochondria. Required for sperm motility and normal sperm flagellar structure.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:33882315}; Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:27811987}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the principle piece of the sperm tail. {ECO:0000269|PubMed:27811987}.
Interaction partners:
Sequence:
MKEDQNYKTAFGSQNSRDTHRHEISFPSQNWSLEMLLRRLKAIDARRDDKFASVMDAIGEFGTFQWRLVVLTFIPSILSTFFIFSHHFLLTAQRPYCNTSWILEVGPNLTEDEQLNLTLPRAPNGSFLTCLMYIPVPWDLDSIIHFGLNYTETCKFGWIYPFAHTRSLINEFDLVCGNEPNKENGLTVFLSGVLTGSLLFGFLSDKLGRYPIILLSLLGFLIFGFGTAFVSSFYQYLFFRFFVAQASVGYAICSVSLVMEWLVGEHRAQAVILQHSFLTIGVILLTGLAYKVVHWRLLCLLGGMPMFPLICNIWVLRESPRWLMVRGKVEEAKKVLCYAAEVNKKTIPLNLLNELQISGKKVAKASILDFCTNQHLFKVVLAIGCVWFTVSYISFTLNLKMNDFGLDVYFVQMVRSIVAVPARLCCIILLEYFGRKWALNLTLFLVTSMCLFLLFLPQEPKSTIILTLMLAEFSMAGTLSIFFIYTAELLPTVLRSTGLGMVSLAWVAGAISSVAIFKQTKTQLPIFFCCLCCVLALCFSSLVPETGSQSLRDSIEYNIRDSIEPKDRNKDVPMVIAEESMSDIVADSEVTNTTLNAVTFKPEENSLLNMTLEVPKMDLPVQSLKAQPP
Protein: Utx histone demethylase, isoform E (EC 1.14.11.68) (M9PCJ7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLKHCGEFHIALKHLQLALLYTYPSTFSELQVKFQIAHLYEVQNKHKAAKDGYEFLLNEKNISLELKADVYRQLGWMYHCVECLGEKKEREANALNFLQKSIEADPKSGQSLYLLGRCYAGINKVHDAFLAYRNSVEKSEGNADTWCSIGVLYQQQNQPTDALQAYICAVQLDKDHKAAWTNLGILYESCGQLRDAYACYLNATKQISFQKSSLIRKKQAIRMKKDTIGLSKGLSQRITFLEGQLSQAPLPSITSKRRQLCSIEEAWNLPISLEMNSRQQQTAQMLPRQVTKQSPVQGPPPPYPHSQLSQSPIPSKRIKEDGTSQQEVTQNNSQTSAQNLINISESLNQRNFNAMPESNKSSEQSVLDTFDDISNDIYKQNESIKLERLSQDALSNNEDSRHDFIGGDNADISTTFKIQMDSKQLMVAVKLLPIDEPPVHCTILQVNAPPPSPPDCPPQKLTRDQLLPPTPSVHLENKKHAFSPQLQEFCLKHPIAVVRGLAGVLKLDLGLFSTKTLVEANPDHSVEVRTQVHQSPDENWDTSQGKRVWACISHRSHTTIAKYAQYQASSFQDSLKDESDKGFPGSQAMSDSDSKDSVSNSNIVLKRKKHKINSKMLRFGTNVDLSDEKKWKPQLTELQKLPAFARVISAANMLSHVGHVILGMNTVQLYMKVPGSRTPGHQENNNFCSININIGPGDCEWFAVPDAYWGGVHNLCEKNNISYLHGSWWPVLEDLYKENIPVYRFIQKPGDLVWVNAGCVHWVQSIGWCNNIAWNVGPLTARQYSLAIERYEWNKVQAFKSIVPMVHLSWNLARNIKVSDTKLFELIKMCLLQTLKNVLHIQEYVKSKGVEIRFNGRGKNEASHYCGQCEVEVFNVLFIKEQEKRHVVHCLSCALKLSPSLQGIVCLEEYRLSELQRVYDSFTLHRTQGLAYTQ
Protein: PAK4-inhibitor INKA2 (Induced in neural crest by AP2-alpha protein-related homolog) (Inca-r) (Inka-box actin regulator 2) (Q9NTI7)
Organism: Homo sapiens (Human)
Function: Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:26607847}.
Interaction partners:
Sequence:
MTMESREMDCYLRRLKQELMSMKEVGDGLQDQMNCMMGALQELKLLQVQTALEQLEISGGGPVPGSPEGPRTQCEHPCWEGGRGPARPTVCSPSSQPSLGSSTKFPSHRSVCGRDLAPLPRTQPHQSCAQQGPERVEPDDWTSTLMSRGRNRQPLVLGDNVFADLVGNWLDLPELEKGGEKGETGGAREPKGEKGQPQELGRRFALTANIFKKFLRSVRPDRDRLLKEKPGWVTPMVPESRTGRSQKVKKRSLSKGSGHFPFPGTGEHRRGENPPTSCPKALEHSPSGFDINTAVWV
Protein: Nuclear cap binding complex subunit CBP110 (Q38BU6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- C3H1-type domain-containing protein
- Nuclear cap binding complex subunit CBP30
- Nuclear cap-binding protein subunit 2
Sequence:
MYAMPGNSGDLQCDDGKKRHIPPLSLLLSGYGSSEGRELDTSYTPKQWLWFLYVTSWARPFFTYASSGGASEATEGSSDNRSGSAYWGRLSFDELLKLSGSPIPPAMVSLWMGLCMPTDDVVQELRIMTEGKAEGRQRIYPFLPRVAESTFGRALRSLAVRQHISSWMPSHAGDVCAALDVLVRDTLEVIQNSADVRKTARVRCEERDASGEEALEGAFRSMLSASTTAPKVVEATTYRPLFDVKASIPEGGTAQVLIRVANAARLFAALSVEAFGRVKSECAVLLLAHINQRDAPEHVDARAYGVVTGVVEYAMAYRYCRDDGTGRCPLTCAALLLHRLVELQGIVEKDTAAGDRCMGMAVSASRFANMTVACIQELLFCVVAGDTVRWHREHQPDGVSVCPTAARTLTLHETDCLLQVFIPALLQQVGFEWPWSESLRHAKMLDRARTQHIVMEDGVRLDSRSVFEELLVSVARRTYGLRLRAILPQSFDVIAENIFVSIHDVPNEGKSSGGNPEKVADNSSSRFALPLYYRTAGEVLLEYFDRCGPSGITAEETERVLRRATDVQPMVVQLQALGGDTNGGITDCVSYCGELSRTVYFSAREKERLLQRYRCEVLLASLVVYTQLRTVSVVQQLTRQLAPLFEQLLLPLAHERTLSRCPVIASRKGDGVDDNGTPLVDLTPEFKMLVDEIHYEFYPLEWVPEAVDAHIRQECGVREKEGAPYHEGGNGPPCFAQYSLFAAIAHQFGLVLEGNPRGFRGGDGSSSEVRTKAYRFFTLMLLNNLGDAVSSSCELDGAAALAATRRVKDCQDGSENCKQRQAAVRQRGGASFHSVVSACDVVVTMTQCLLPAHLSSHPRMATTGSMSNEWMRRVGEWTRSAYSKYTAYQQQVHGLDLPVPLISLYNSLTFDSVPLARETIRAVRSRLLEKMSVVTASPPGDVETAGKQLLEQHLSSLTVTLTAVGLLPLCVRGGSHVPCATQLLWASPFFSHELLHCGRYEVSV
Protein: tryptophan 5-monooxygenase (EC 1.14.16.4) (Q6PBX4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MYSSKSDGPRRGRSFDSMNLGMTLEEKQLNNEMNKSAFTKIEENKDNKTESSETGRAAVVFSLKNEVGGLVKALKLFQENHVNLVHIESRKSKRRNSEFEIFVDCDSNREQLHEIIQLLRKHVNVVEMDAPDNRLPEESEMENVPWFPKKISDLDKCANRVLMYGSDLDADHPGFKDNVYRKRRKYFADLAMSYKHGDPIPRIEFTEEEVKTWGVVFRELNKLYPSHACREYLKNLPLLIKHCDSREDNIPQLEDVSRFLKERTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDDSIQKLATCYFFTVEFGLCKQEGKLRAYGAGLLSSISELKHALSGNARILPFDPNVTCKQECIITTFQDVYFMSDSFEEAKVKMREFAKTIKRPFSVRYNPYTQSVDVLKDTTSINNVVEELRHELDIIGDALSRLNKQLGV
Protein: SH3 and PX domain-containing protein 2A (Q1LYG0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation.
Subcellular location: Cytoplasm {ECO:0000250}. Cell projection, podosome {ECO:0000250}.
Interaction partners:
- Hematopoietic cell-specific Lyn substrate 1
- Cortactin.
- WASP-like actin nucleation-promoting factor a.
- Actin nucleation-promoting factor WAS
- WASP actin nucleation-promoting factor b.
- Growth factor receptor-bound protein 2
- Cytochrome b-245 light chain
- ADAM metallopeptidase domain 12
- WASP-like actin nucleation-promoting factor b.
- Cofilin 2
Sequence:
MQFRTVLDVKVVDVEKRRNPSKHYVYLINVTYSDSTSHIIYRRYSKFFDLQMQILDKFPIEGGQKDPKKRIIPFLPGKILFRRSHVRDVAMKRLRFIDDYCRALVRLPPQISQSEEVLRFFETKPDDINPPVEDYGSKRKSGLDSSEPMVLEQYVVVANYERQENSEISLKAGETVDVIEKSESGWWFVSTAEEQGWVPATYLDSQSGTRDDLDLGTSRSGEVTKRRKAHLKRLDRRWTLGGIVNRQQSREEKYVSVQAYASQGKDEIGFEKGVTVEVIQKNLEGWWYIRYQGKEGWAPASYLKKLKDDLSPRKKTLTGPVEIIGNIMEISNLLNKKAVSEKDIQTDGEATTPERHISKSEISLPMPYAPEAGVAPTVVTALGMNSGSSATLQENKSRAEPGSPAIARVAPHRVEIGSPNLRQKPPPRRDANLAFQLPKPPEAPTVEAEYYTIAEFQSSISDGISFRGGQKADVIEKNSGGWWYVQIGDTEGWAPSSYIDKRKKPNLSRRTSTLTRPKVPPPAPPVKKQDSEEGPSLGGSASKAPESPQRVYEEPEYDVPALGFDSELDCNPPKPKTHNSPKPEPRKFEIKSNPAAAERIAQAGKASPLLKVMTSPLRKRNSLENINKEEVIYENEGFRFSSDDFASGCDSHTPRSLTLGRKPFGSSSGGGKPLRKVSPDLNRSHSLGRAERHSSKLFSDESARNPKREPVMRKDVEIRIGQSPLARPKPVVRPKPLLTKSEPQSPERMDISSIRRHLRPTGSLRQGAIRAMRGEDSETASVVSSEDSTSSRSTSDLSSVYSKGSRGGESDHESVLFRTTDAYERAQESELSFPAGVEVEVLEKQESGWWFVRWGSDEGWVPTFYLEPIKHTHNVGIQESRDSPLVDLGSTNKSNSLEKNEQRVQALNNLNQQNLRSMSNPSPPIPSKPPGGFSKPTAMLNGSSVRMRNGVRQAAVRPQSVFVSPPQPLKETNIHTGSLRRNESLGAGDHLRSTGGVRRNSSFTAVRPQPVTDVRVRAGTTITAPAGSSSPLIAQRNGIPISTVRPKPIEKMQLIHNNLREVYVSIADYRGDEETMGFSEGTSLEVLEKNPNGWWYCQVLDGLQGRKGWVPSNYLERKK
Protein: Phosphoribosylpyrophosphate synthetase, putative (EC 2.7.6.1) (Q38A32)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Transketolase
- Ribose-phosphate pyrophosphokinase, putative
- Ribokinase
- Ribose 5-phosphate isomerase, putative
- Orotidine 5'-phosphate decarboxylase
- NUDIX hydrolase, conserved
- ribose-phosphate diphosphokinase
- ribose-phosphate diphosphokinase
- inorganic diphosphatase
- inorganic diphosphatase
Sequence:
MSSSTCAFSANLSANRNGNLRVVHGRSNPKLAEGICKALGIPITGCRVGAFANGEINLQVVESIRGDDMFIIQPTCGNGNINVNQAVMELLLMIHTLKLSSARRVIAVIPHYGYARQDRKQSARVPISASAVARMITELGVNGVVTMDLHCGPIQGFFHGCPVADLSATSEFAAYGKSKMFDTKELAIVAPDAGAVNRARRMGDRLGARRIVTILKRRVEANEVDSMQLVGEVKGCTCIIVDDMIDTAGTLCKAAQVLKEHGAKEVHAWATHGILTDPACERINDCPALVEVVVTDSLPQDESLQKCSKLKIISIAKLLAEAIQRIHCEESLERVGDMSAPTPHDQDLISVDALVEDSDWSAALQPHIIKRATGATP
Protein: RNA-binding protein, putative (Q381I4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RNA-binding protein, putative
- Ribosomal RNA-processing protein 12-like conserved domain-containing protein
- CCAAT-binding factor domain-containing protein
- ATP-dependent RNA helicase
- Pumilio/PUF RNA binding protein 8, putative
- Bms1-type G domain-containing protein
- ATP-dependent DEAD/H RNA helicase, putative
- Nucleolar complex protein 2
- Nucleolar GTP-binding protein 1
- Nucleolar protein, putative
Sequence:
MAAALLKRKATPSMMRRKKAKQRIRKKLQRKIERKKSNWKVAIAKTYDSGNAKGKKDERFRGKKKRSGDDDETHSTPEDVEEEVQSDIDEEKQERLNKQDPLETQLFLKRLPLDTSEEELLNFFQTRFGGVRRVLLVRNSRTKTLAGTGFIHCGTVEMADKIFDHAQQNARELSANDRADWREQTKDLSHCRAKRLLFKNRADAFNSREPFMTLRETRFTVHRVLSRKDSHDATAAQQKKKKRTKVAADDPRHLYLLQEGLILPDTPAARGLHPRYIEMIRADYESRKNQLRDSNMFVSTTRLSVRNLPRTMGEKELRLLFSTHVRSFLKKNKNFADKSNWGKYGPIKNVKIVKDSAGTSKGYAFVELVNHPVALHALRALNNNPTIFGDHRRLLVSFAIEDINALQKLKRIRELRRQRDAALLNKSSNNEAN
Protein: UPAR/Ly6 domain-containing protein twit (Protein target of wit) (Q9VII3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000269|PubMed:22467519}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:22467519}. Presynaptic cell membrane; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:22467519}. Secreted {ECO:0000269|PubMed:22467519}.
Interaction partners:
- RE19849p
- Uncharacterized protein, isoform B
- GEO08076p1
- IP04187p
- UPAR/Ly6 domain-containing protein CG9338
Sequence:
MSAVPMKAFLAGLFLLANAWHITAINEQHQKHHLQCWHCSSDTIGAEDFCDVTFQEDNIPTDLIKERNINLLRSCNGTINSDHERAVCRKTVEENNGKLITKRFCYYTNKSDPVELCNITSPEKNVRRIFCEDCLTDRCNGALAGASILEMLLLLPIAGLIQQFAI
Protein: Short stature homeobox protein (Pseudoautosomal homeobox-containing osteogenic protein) (Short stature homeobox-containing protein) (O15266)
Organism: Homo sapiens (Human)
Function: Controls fundamental aspects of growth and development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}.
Interaction partners:
- Arylsulfatase L
- CD99 antigen
- Steryl-sulfatase
- Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
- Sex-determining region Y protein
- Transcription factor SOX-5
Sequence:
MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL
Protein: Ctr9, isoform A (Ctr9, isoform B) (LD24034p) (Q7K0X3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RNA polymerase-associated protein Rtf1
- Uncharacterized protein
- Hyrax
- RNA polymerase II-associated factor 1 homolog
- Transcription elongation factor SPT5
- Transcription elongation factor SPT6
- FACT complex subunit spt16
- FACT complex subunit Ssrp1
- Transcription elongation factor SPT4
- Another transcription unit protein
Sequence:
MSNCIEIPLQDTDEVIEVDPDQLPDCPEVLSILKQERAPLHVWVNVALAYYKQKKTEDFVTLLEESRSDDATKEYRDSDKDLMRALDMLAAHYVQEAYREKSKDKKRELFMKATNLYTSADKIIMYDQSHLLGRAYFCLLEGDKMDQADAQFNFVLNQSPSNIPSLLGKACIAFNRKDYRGAMAFYKKALRTNPNCPANVRIGMAHCFLKMGNPEKAKLAFERALQLDQQCVGALIGLAVLKLNQLEPESNKLGVQMLSKAYTIDNANPMVLNHLANHFFFKKDYQKVHHLALHAFHNTENEAMRAESCYQLARSFHAQSDYDQAFQYYYQSTQIAPANFVLPHYGLGQMYIYRGDTENAAQCFEKVLKIQPGNYETMKILGSLYAHSNSQTKRDMAKTHLKKVTEQFPEDIEAWIELAQILEQNDLQASLSAYGTASSILRDKAKYEIPAEIQNNVASLHYRLGNLKMAKLTLESALKHATSEMDKDVKYYESIQVTMKYNLARLNEAMSSYDVADKLYKEILKEHPNYIDCYLRLGCMARDKGLIFVASDFFKDALNINNDNPDARSLLGNLHLAKMQFALGQKNFETILKNPSTSTDAYSLIALGNFSLQTLHQPSRDKEKERKHQEKALAIFKQVLRNDPRNIWATNGIGAVLAHKGCVIEARDIFAQVREATADFCDVWLNIAHVYVEQKQYISAIQMYENCMKKFYKHNNVEVMQYLARAYLRANKLVDAKAVLLKARRVAPQDTVLLFNIAVVLSRLAMAILKDEKSTLEIVLQAVHELELAQKYFQYLSVHGDKNRFNIEVAGIEASTCQDLLSQAQYHVGRARRIDEEERSLRRKQEEEREAFKIKVAEQRKRREEEAKTSRDQLLAKRQEYVEKTKNMLIIADAPPEKERKKGGGRGRKDDYISGTESDNDGARREGERPSKKKGKGERKKGGGRKRKTEKYESDSEEEPGASGKSGKKKGKKPKPVKESKEKLSAKQRLKVLSKETISTSESESDGKRSKSRSRSRSRNRSGSRSGSASRSGSDREASRKRSRSRSGSGSGSDSDEATKRKRARNRIESGGESDRSGSRARSKSSSRSRSRSKSGSRSRSRSKSGSRSRSRSKSGSRSRSRSPSGSRSRSRSGSRSKSESRSRSGSPEK
Protein: Acyl-CoA-binding domain-containing protein 6 (Q9BR61)
Organism: Homo sapiens (Human)
Function: Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18268358, ECO:0000269|PubMed:37951597}. Nucleus {ECO:0000269|PubMed:37951597}.
Interaction partners:
- Glycylpeptide N-tetradecanoyltransferase 2
- Glycylpeptide N-tetradecanoyltransferase 1
Sequence:
MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA
Protein: Acyl-CoA synthetase family member 3 (F5H755)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSIT