wanglab/gogpt-training-data huggingface dataset:
Protein: Cadherin domain-containing protein (Q8CE10)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
SLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQNDNAPKILYPSLPTDGSTGVELAPRSAEAGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFTVGLRSGEIRTARALLERDALKQSLVVAVQDHGQPPLSATITLTVAVADSIPDILADLGSINTPADPDSDITLYLVVAVAVVSCVFLLFVLVLLALRLRRWHASHLLQDAMGGSTGVPTSHIVGVHGVQTFLQTYSQEFSLTPDSGKSHLIFPQPNYADTLISQESCGKSEPLCSSVEPKFPIDDTPLVPVSSGLFFSLLSMIILS
Protein: Pentacotripeptide-repeat region of PRORP domain-containing protein (Q580V1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Small ribosomal subunit protein mS41
- Enoyl-CoA hydratase/isomerase domain-containing protein
- Ribosomal protein S9
- Uncharacterized protein
- Uncharacterized protein
- Opioid growth factor receptor
- LysM domain-containing protein
- Uncharacterized protein
Sequence:
MLSQNVAKTTVPSYYMIRTNLPHRKPQNQWEGVYYYSGITKRQRHLILLHRKREREAHMRSFNISRASVLQRLEQLSGDRKQESLPPHVRLDLAVRLAQHGLYQQATPIVDELHHQKALHAGHYALLINALACPRLGQRILHCDAQCDPALTYKLLGDENGEERAQEAYRWFDLALTSLAVDCGGRTQPSQFVRYLPQGTAAASHITNALMRTLLTCGYTHVAAIPDSVYDRMGSMGISPTISTYELVMLALSLQGNMVEAESILSFLRSHHSEHITVESFNALLLGHREARQFDCCDAIWQELVDRRWPRASPLTAELYLRSIMDHANTPTSEPLQSFANINVVEKKKVPLVLAQMDELGVPRTHLSRVLMDEVEDSLRKFQTYRSRFYEWGRAVKQFDFIEFRRRNGWLYDLHLMKCTTKQVGPLRDFNDPDAVQGAVATAEIPAFFNERPAWERPPLEETLYVTTNKERYDDVRGGDIYYDDTRSLHDRSPTWMNEVPETRYDRLYGVNHPDIAKIGIRRHLNVEYVNRKEVVERDAALMKKTLSSGRRLRHRVESSRTHRNAGSLSGISSTAGGGSR
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A2A123)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSSRNIEWEHFEEREKGHRSPRGSGGSHSGSRGNGIVPSPAHSAHCSFYRTRTLQSLTSEKKAKKVRFYRNGDKYFKGLVYAVSGDRFRSFDALLMELTRSLSDNVNLPQGVRSIYTADGGKKITSLDDLVEGESYVCASNEPFRKVDYTKNVNPNWSVNVKTGASRSMPSLTATKNELRERESKDYIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGAVKRLYTLEGKQIICLQDFFGDDDVFIACGPEKYRYAQDDFVLDHSGKASTAFITECQVIKSSYSARSAPPVRYSGSKSPGTGRRSKSPGSARRTAGHFSTNSQSPVKSPINGAPNSQITTPKSAKSSSSSPTSPRSMRNFKIPTHHSSAGNVNGSSETPQHHNNSLSPEVNGNRNLAASTILDKYKIGKVIGDGNFAVVKECVERSTGKEFALKIIDKNKCRGKEHLIENEVAVLRRVKHPNIIMLIEEVDTPAELYLVMELVKGGDLFDAITSSTKYTEKDASVMVFDLAAALKYLHRMCIVHRDIKPENLLVCEYPNGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAESGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILLGHLEFPSPFWDNISDSAKELIGHMLQVNVEARYTAEDVLSHPWVTEDAAMENNMKMEVAGKLKKHFNSVQKQSNTSAGVSVIMLQGNEHSSR
Protein: Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3) (Liver regeneration factor 1) (LRF-1) (P29596)
Organism: Rattus norvegicus (Rat)
Function: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites (By similarity). It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Transcription factor Jun
- Protein c-Fos
- DNA damage-inducible transcript 3 protein
- Mothers against decapentaplegic homolog 3
- Transcription factor JunD
- Cellular tumor antigen p53
- Transcription factor JunB
- Cyclic AMP-dependent transcription factor ATF-4
- Cyclic AMP-responsive element-binding protein 1
- Histone deacetylase 1
Sequence:
MMLQHPGQVSASEVSATAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTINNRPLEMSVTKSEVAPEEDERKRRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQS
Protein: Aldo-keto reductase family 7, member A2 (Aflatoxin aldehyde reductase) (Epididymis secretory sperm binding protein Li 166mP) (V9HWA2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR
Protein: AAA+ ATPase domain-containing protein (Q584X8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPLAYLQGEILDMEKYRTEEAVWSRNTVREAWNAINHTLHDTTPGVDATKKKEIIEKDLVGLALCTSYAEVKHLLSLLTPSLRSHIVSQPSYKQTEVEEFFLHLGQDIEVRGADWVIQVPPPSVTDLRYTLERVGRFGDDGRGCIGHTPHRVAVWRGRLGEPLGLTIRVGRYVPNVARALVPLARRGSVLILSKAGMGKTTILRDLAASLSRDPAKPRVMVVDTSNEIGGDSPMPLPFLGRCRRIQVPRREEQQEVMKQILQNHSPEYVIVDEVSTTAEAEVTWSISQRGVHLVATCHGESLAGLLQNQSLNLLVGGTAHAFLSNEERRLRNKIKKTILERPHSSPFKFVVELHSRKFAHLYVDVNQAVDCLLDQGDARRSARIGKTIAIDEPLPDEVMGLVMSQEKEGSYAREPSHESWSECNDDDSCALAGREGWRPNNRPERQRGTRSHGCRKRSNDDLLDELNNFN
Protein: Lipase (Q22060)
Organism: Caenorhabditis elegans
Interaction partners:
- CHK kinase-like domain-containing protein
Sequence:
MLRRFVLLGLVCLSIVNAASDVAGPLTDDFQSWLIANGYSSYDFVRADYGTQGSYGGKTANAPKAVNTPVVFIHGNSDAALHVSSAATGWSNSIEYFLEHGYTVAELYATSWQDTNALHAASRTHNCKDLVRLRKFLEAVLAYTAAPKISVVTHSMGVTLARKIIKGGSVSASDGSCDLGLPLNKKVEVMIGISGANYGLCNCEGGSATLEKTCNRVNGLWPGDSCGLNYLDCGLTPLPWPCSGVNYSSFLMQLNADKNKEGDYVFSMWSLSDDLIEYGTQVWGRSTCFIPTSDGKVVYHVYTHMETKELTYVDQYQMVKYKTIPTPTA
Protein: Syntabulin (F1LUC0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Kinesin-1 heavy chain
- Kinesin heavy chain isoform 5A
- E3 SUMO-protein ligase RanBP2
Sequence:
MGPLRESKEQRVQHQEKEFSRSRIPRLILRPHLPQQQQQQQNKVSPASESPFSEEESREFNPSSSGRSARTISSNSFCSDDTGCPSSQSVSPVKTPSDTGHSPIGFCPGSDEDFTRKKCRIGMVGEGNIQSARYKKESKGGIIKPGSEADFSSSSSTGSISAPEVHMSTTGNKRASFSRNRGPHGRSNGAPSHKSGSSPPSPREKDLVSMLCRNPLSPSNIHPSYAPSSPSSSNSGSYKGSDCSPVMRRSGRYMSCGENHGVKPPNPEQYLTPLQQKEVTVRHLRTKLKESERRLHERESEIMELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHNSSLRDELCLDFSFDSPEKSLPLSSTYDKMADGLSLEEQITEEGADSELLVGDSMAEGTDLLDEIVTATTTESGDLEFVHSTPGPQALKPLPLVSQEEGIVVVEQAVQTDVVPFSPAISELLQSVLKLQDSCPTSSASPDESGADSMESFSESISALMVDLTPRSPNSAILLSPVEIPFSKAATEARANRLMRELDFAACTEERLDSILSLSQGGVVRQYWSSSFLVDLLAVAAPVVPTVLWVFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFHMKT
Protein: Missing-in-metastasis, isoform F (A0A0B4JCZ8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDLSLERDSSALGSLFQQIINDMKNTSPLWEDFVAKAGKLHTCLRAAIQAIAAYLDAFQKIADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARKGQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAMQSIALVTKEPSVLPQASEELIHDAKASINLYPESPGGGSGSQGGGCSNSLGSRKSSVCSISSMNSSGSSNSPGHHHYPRSLSQTSNATNQTANVSTWPPHSQDGVDTLPPTADRPHTISTAYEKGHQRPPLTVYTFQNPETIHESGSCLNNGTAAPNGQPLSGQATPATQKSPAASLSRPPLPVRCSSLERPLSAQSNHRQGSGNNLLQRQCPSPIPAHITKELSAAHHAQQQQQQQNQQPQTPPTYVNMSELATMAALKQTNQQQKPSTPPLQQQSSIDSTSSQHSNDSTGSHQLLQQQQQHHQSQQNHHSATATRSHSISSTASSLHSHPSIDSTVACGSLVGQHNHSTSTNTNTTSPSSGSSTPQNHYSPLLTNSPTSTAAGTPSGSSLGPGSGLGFVYQVSSPTPPSSEVLKITEQAAAGQDQGPANSVADETDERSRASVLQKASMFEKAAAAAAVSPPAPMQIASGSPASGGGTRRSEAEQQEMDKSFEDSIQALNNLIGELDSFQREIDEGKVKPPSNIISGSTTSSNNNNTTTSSISSSDNNNLPATSNIEPCAISNQTNSSGCGTDISDTTSDELAGDDMDVRRRDRDRDRDLLGASDSELSRCYVSETSSLTGGLTAGGYENPTFAHFAANANREDAVSLASDSVCLGQPRHAYVDTCSDSGSAVVVIYDHQIPNTPDIEFVKQNSEIVVLRTKDPQPHALQLHEMRELQQLPANLAGSPDSSPDSAGGQAPPTATVAPAKQRLSSFRATSEQQLQLLGRGSPQRGKTPSEQAVQSRPQDQHFPQTQQQDIDGSSPPVELARRQLPPKPTSLSIFNGPVPTAGDRPVVPRKSDFKADLDAKIRRQKQKVKQQLQQQQQQQQQEQQETQQQQQAPQEQQHSPQSPQTRNCNVTNQQAANITASASAFATATASTDPYPNPNHRMPNQNQTATSNHTQCKTPTMALSPSSPRGHLPLSSSSLSSLPLPATTSSPSNARPSMLPASDRPPAHPYVCSNAPANPHHANSISNANAHLKPCITPRPASLSGGAAGGGSTRIGRRSSINQSKPPPPVRRSSSVTPSPNASVGLQQQPQHATLSQQNHQLSSSSEHLPPPPPFMLDAMPQIPSSALKVSETVRALAAMRHQPASPVSLRRMQQQQQQQLQQQQQQQVQQQQPLLQSAHNSPLKEDLTVYYDSYLDLHAYAQALASGQQPGGQQMANQQRFTLQQQHQHLHQPQQPPVYQVDATFRTSSPAAGGGGGGGIYAQPKLVNSMSSFRTSSPSPNGHAHPLPPTQPKANPNLIAQLNARLSGKQQQHQQQQHIEGIYGNQQAPGGESIYMRSGLSMSQPQQQQHFDGKSEQIQLQHQQQHRIYASFGTSSSAMSSAHAANSSTKPSILTPTTSFNALPHFPLSSSTSSLLSKVSSFSNSSSASPPTTAATSGSASSHYQPPQPPNAAVANSKDMAIYSSSFTKNPAAAQSPNMRQAHSHQHHQPPQQQHYTCPPPLEDPPPPPIYAAGASATMPKKMARPPTGQNATHSSAYAAASSTATLPKNMMQQQQRLQHQQQYQQPAGMGIGNGNGHLGQRPQLPLPQQKLRAAQQQHLAEQQHQQQQEQQQHHQQHQQHQQRQPPIPSRHSSVQQKIFVSTNPFIQTTAVKFHSPSASPTCGSPVTGSLASIYATTSRGGHHHQQQQAQQQQHYYRDAAGGNSNGGAAYYNHNAHAHSQAHHPNYATSTNIEKTGSIRAKTKAEFLENLNAKLAKQGMSGRAFAVRNLINSKALMYQNPQKLSRPSAQYRRPPTYPNTSTTTNATCEDQC
Protein: F13M7.16 protein (Ubiquitin-associated (UBA)/TS-N domain-containing protein) (Q9MAT3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Plant UBX domain-containing protein 11
- Plant UBX domain-containing protein 3
- Plant UBX domain-containing protein 4
- Plant UBX domain-containing protein 5
- Plant UBX domain-containing protein 6
- Uncharacterized mitochondrial protein AtMg00600
- At1g58420
- Plant UBX domain-containing protein 2
- Cell division control protein 48 homolog A
- Cell division control protein 48 homolog D
Sequence:
MAGVSLKCGDCGTLLKSVEEAQEHAELTSHSNFAESTEAVLNLVCTTCTKPCRSKIESDLHTKRTGHTEFVDKTLETIKPISLEAPKVAMEIDDNASGSGEAAEEMVVPDVDNNILEELEAMGFPKARATRALHYSGNASLEAAVNWVVEHENDPDVDEMPKVPSNSNVGPAKPALTPEEVKLKAQELRERARKKKEEEEKRMEREREKERIRIGKELLEAKRMEEVNERKRLMFLRKAEKEEEKRAREKIRQKLEEDKAERRRKLGLPPEDPATAAAKPSVPVVEEKKVTLPIRPATKTEQMRECLRSLKQAHKEDDAKVKRAFQTLLTYMGNVAKNPDEEKFRKIRLTNQTFQERVGSLRGGIEFMELCGFEKIEGGEFLFLPRDKIDSAIINSAGTELNSAINNPFFGVL
Protein: Glycine cleavage system H protein (Q53XL7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|RuleBase:RU364055}.
Interaction partners:
Sequence:
MALRVVRSVRALLCTLRAVPLPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWVTTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEVTEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE
Protein: PAXIP1-associated glutamate-rich protein 1 (E7F1D2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Aspartate beta-hydroxylase domain-containing protein 2
- Double C2-like domain-containing protein alpha isoform X2
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- Proline-rich transmembrane protein 2
- Seizure-related 6 homolog
- Protein yippee-like 3
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
- HIRA-interacting protein 3.
- Lysine
Sequence:
MQEAQDTLAERVESLGVGERDKTGEKEEQKEKDGDETSTAATHTPTEDNTAEGQKELREEQKEGTSTDGEVNGGEGQTQQQEVEEEEWMIPYSDEEMEEPQNWMPPPAEIKRLYELLAKGEELELQWVPLPRRPPTPPRTPSPEGDGDDTQDHTQEQAERKALTPTEFDFDEEQTLATPKNSFLTRRRTPGSSARSTVKREARLDKVLSDMKRHRKIEEQILRTGRDLFKSDKARAGPAIEKPLSPNSQREREKERERDSDPSTVFSPRQRRY
Protein: Autophagy-related protein 13 (Q91YI1)
Organism: Mus musculus (Mouse)
Function: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:19211835, ECO:0000269|PubMed:19258318}. Preautophagosomal structure {ECO:0000269|PubMed:19211835, ECO:0000269|PubMed:19258318}. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome. {ECO:0000269|PubMed:19211835, ECO:0000269|PubMed:19258318}.
Interaction partners:
- Autophagy-related protein 101
- Serine/threonine-protein kinase ULK2
- RB1-inducible coiled-coil protein 1
- Serine/threonine-protein kinase ULK1
- Autophagy-related protein 9A
- Beclin 1-associated autophagy-related key regulator
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Beclin-1
- Regulatory-associated protein of mTOR
- Serine/threonine-protein kinase mTOR
Sequence:
METELSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALSGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLNGLGEGFQTVRVGTVGTPVGTLTLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTAEDAGVAYPSVEDSQEVCTTSFSTSPPSQLSSSRLSYQPAVLGLGSADLAYPVVFTAGLNTTHAHQLMVPGKEGGVTLAPSHPTHGAQADPERLVMHMPSDGTHCAATPSSSEDTETVSNSSEGRASPHDILETIFVRKVGAFVNKPINQVTVTSLDIPFAMFAPKNLELEDADPMVNPPESPETTSPLHGSLHSDGSSGGSGGSTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDFGAQSMAEDLDSLPEKLAVHEKNVREFDAFVETLQ
Protein: Cysteine synthase 2 (CS 2) (EC 2.5.1.47) (Cysteine synthase-like protein) (CSl) (O-acetylserine (thiol)-lyase 2) (OAS-TL 2) (O-acetylserine sulfhydrylase 2) (P87131)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, in contrast to cysteine synthase cys11, this CS-like protein seems not to function in cysteine biosynthesis, at least under normal growth conditions, although the transcript is produced.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:P53206}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sulfite reductase subunit beta
- Homocysteine synthase
- Probable sulfite reductase flavoprotein component
- Cystathionine beta-lyase
- Probable cystathionine gamma-synthase
- Adenosylhomocysteinase
- Sulfide:quinone oxidoreductase, mitochondrial
- Putative serine acetyltransferase
- Putative phosphoserine aminotransferase
- Glutamate--cysteine ligase
Sequence:
MAKKYQDLASGIAMGAVFMYLLRRLYESLRVKSSADSLEEDIVNGVEGLIGNTKMVRIKSLSQATGCDILAKAEFLNPGNSPKDRVALQMIRTAEENGDLVPYQSNAVYEGTAGSTGISIAMLCCSLGYDSRIYMPSDQSKEKSDILELLGAHVQRVTPAPIVDPNHFVNTARRNAANHTVDESIPGKGYFANQFENPANWQAHFNSTGPEIWRQCAGKLDAFIAGSGTGGTIAGISRYLKSKDPSITVCLADPPGSGLYHKVLHGVMFDLAEREGTRRRHQVDTIVEGVGINRMTRNFSIAEPLIDMAYRVTDEQAVAMSRYLVTHDGLFVGSSSAVNCVAAVRLAKKLGPGHRIVTLLCDPGSRHFSKLYNEEFLRKKNIVPQVPSSLDFVEA
Protein: Matrix protein 2 (Proton channel protein M2) (J9V8B5)
Organism: Influenza A virus (A/England/250/2009(H1N1))
Subcellular location: Virion membrane {ECO:0000256|HAMAP-Rule:MF_04069}. Host apical cell membrane {ECO:0000256|HAMAP-Rule:MF_04069}; Single-pass type III membrane protein {ECO:0000256|HAMAP-Rule:MF_04069}. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion). {ECO:0000256|HAMAP-Rule:MF_04069}.
Interaction partners:
Sequence:
MSLLTEVETPTRSEWECRCSDSSDPLVIAANIIGILHLILWITDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYQQEQQSAVDVDDGHFVNIELE
Protein: Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase) (Q61024)
Organism: Mus musculus (Mouse)
Interaction partners:
- Argininosuccinate synthase
- Aspartate aminotransferase, mitochondrial
- Cyclic AMP-dependent transcription factor ATF-4
- Aspartate aminotransferase, cytoplasmic
- Adenylosuccinate synthetase isozyme 2
- Adenylosuccinate synthetase isozyme 1
- Multifunctional protein CAD
- Isoaspartyl peptidase/L-asparaginase
- SUMO-conjugating enzyme UBC9
- N-acetylaspartate synthetase
Sequence:
MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVRKYPYLWLCYNGEIYNHKALQQRFEFEYQTNVDGEIILHLYDKGGIEKTICMLDGVFAFILLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVSLKHSTTPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCTDEPLHAIYDSVEKLFPGFDLETVKNNLRILFDNAIKKRLMTDRRIGCLLSGGLDSSLVAASLLKQLKEAQVQYPLQTFAIGMEDSPDLLAARKVANYIGSEHHEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLKELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPDMRIPKNGIEKHLLRETFEDCNLLPKEILWRPKEAFSDGITSVKNSWFKILQDYVEHQVDDEMMSAASQKFPFNTPKTKEGYFYRQIFERHYPGRADWLTHYWMPKWINATDPSARTLTHYKSAAKA
Protein: Beta-1,4-galactosyltransferase 6 (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (EC 2.4.1.-) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6) (UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6) (O88419)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity).
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:P15291}; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack. {ECO:0000250|UniProtKB:P15291}.
Interaction partners:
- Ceramide glucosyltransferase
- Lactosylceramide 4-alpha-galactosyltransferase
- Beta-1,3-galactosyltransferase 4
Sequence:
MSALKRMMRVSNRSLIAFIFFFSLSTSCLYFIYVAPGIANTYLFMVQARGIMLRENVKTIGHMIRLYTNKNTTLNGTDYPEGNNTSDYLVQTTTYLPQNFTYSPHLPCPEKLPYMRGFLSVNVSEISFDEVHQLFSKDSEIEPGGHWRPQDCKPRWKVAVLIPFRNRHEHLPIFFLHLIPMLQKQRLEFAFYVIEQTGTQPFNRAMLFNVGFKEAMKDRAWDCVIFHDVDHLPENDRNYYGCGEMPRHFAAKLDKYMYILPYKEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVHYSGYNVTRPEGDLGKYTSIPHHHRGEVQFLGRYKLLRYSKERQFIDGLNNLLYTPKILVDRLYTNISVNLMPELAPVEDY
Protein: RNA helicase (EC 3.6.4.13) (B5BTY4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVGATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Protein: Carbamoyl phosphate synthase large chain (EC 6.3.4.16) (EC 6.3.5.5) (Carbamoyl phosphate synthetase ammonia chain) (P9WPK3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Dihydroorotase
- Carbamoyl phosphate synthase small chain
- Aspartate carbamoyltransferase catalytic subunit
- Orotidine 5'-phosphate decarboxylase
- Probable export or membrane protein
- Argininosuccinate synthase
- Ornithine carbamoyltransferase
- Glutamate synthase large chain
- Bifunctional protein PyrR
- Amidophosphoribosyltransferase
Sequence:
MPRRTDLHHVLVIGSGPIVIGQACEFDYSGTQACRVLRAEGLQVSLVNSNPATIMTDPEFADHTYVEPITPAFVERVIAQQAERGNKIDALLATLGGQTALNTAVALYESGVLEKYGVELIGADFDAIQRGEDRQRFKDIVAKAGGESARSRVCFTMAEVRETVAELGLPVVVRPSFTMGGLGSGIAYSTDEVDRMAGAGLAASPSANVLIEESIYGWKEFELELMRDGHDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQRMRDLGIAILREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITGETPACFEPTLDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALGKVMRSLETTRAGFWTAPDPDGGIEEALTRLRTPAEGRLYDIELALRLGATVERVAEASGVDPWFIAQINELVNLRNELVAAPVLNAELLRRAKHSGLSDHQIASLRPELAGEAGVRSLRVRLGIHPVYKTVDTCAAEFEAQTPYHYSSYELDPAAETEVAPQTERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAGFETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVYHAEMESGSGGPGVAGVIVQLGGQTPLGLAHRLADAGVPIVGTPPEAIDLAEDRGAFGDLLSAAGLPAPKYGTATTFAQARRIAEEIGYPVLVRPSYVLGGRGMEIVYDEETLQGYITRATQLSPEHPVLVDRFLEDAVEIDVDALCDGAEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIAKVRKATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGATIAQLRAEGLLAVTGDGAHAARNAPIAVKEAVLPFHRFRRADGAAIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAQGTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDDVRKHFEPAQPGRPTMSAVDAIRAGEVNMVINTPYGNSGPRIDGYEIRSAAVAGNIPCITTVQGASAAVQGIEAGIRGDIGVRSLQELHRVIGGVER
Protein: Ecm33p (A0A1D8PCY4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
- Probable circularly permuted 1,3-beta-glucanase TOS1
- 1,3-beta-glucanosyltransferase PGA4
- pH-responsive protein 2
- Cell surface mannoprotein MP65
Sequence:
MQFKNILAITAIAGLASAANNSTLTTATPSVKSECSFKDFTATASNQVQQVAACATAVGDITIQGESFGTVELTGVQQIYGSLHVKNATKATTINAATLQLVSGVLEFNANTILSDLNLAQLTTVGSFNLNALPALEKTGLTAGITSAESVVISDTGLSSLTGINVFKLKVFNVNNNDNIDTIDSGLQEVTDTIDISYNAEKVDVILKQLSSAKNIVLQQVNSFSAPNLTIANGSFAVSSCSVEKVELAELTSIGNSLTINKNDDLTELDFPKLKTIGGALQISDNSELRSFSGFPKLESIGGSVNINGTFDNGTFESLKRVSGGFILKTDGKLSCSAFNKLNTNGDIKGDKFQCEDRQTTSSSSSKKSGSATETSGSSETGSDSSSSASGSSSSSKKGGAASNNGKLASVVAAFAAVGVALF
Protein: MiRP K channel accessory Subunit (Q27GU3)
Organism: Caenorhabditis elegans
Interaction partners:
- BTB domain-containing protein
- MinK-related peptide, potassium channel accessory subunit protein 4
- MPS-3
Sequence:
MHKNISPTCQEGIREACITLKNACDPQVLDKAAIRMREYENEFGRILYTISILIMFSFVIILLMVRSIRRTQSTVEMDSLLDAMRIREELEIQERKRRRLMRAKTQVTAWLVNKNKEKGPEKRKDSEWKPLPNGTRPRGHYSISTVTSDIPEIVVSADDCIHSDFPNRPHTPAISMIYDFGIASPDLIEPDSRKPSISSSTAIPMSSSSSSSMNSLIEPNMNSIKSNPRTYSLDTNASTSSRTPRVDCDDKSFSLDV
Protein: Tim10-like domain-containing protein (Q389I9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQPPTPPMTPFEQRATQAFQSVGALRMQSNILHRSAAFCMERCLDTEELYTLLRTSQAPIRYRLDTDLAEKKCASNCSAKWDELYRATAMRLNEEAVRRVQMRQMQNMMNAMQGGGV
Protein: Probable deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase) (Q9P6Q5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Interaction partners:
- Probable thymidylate synthase
- Thymidylate kinase
- Deoxycytidylate deaminase
- Nucleoside diphosphate kinase
- Inosine triphosphate pyrophosphatase
- Ribonucleoside-diphosphate reductase large chain
- Coronin-like protein crn1
- Uracil-DNA glycosylase
- Adenylate kinase
- Hypoxanthine-guanine phosphoribosyltransferase
Sequence:
MSFFVQKLSEKATIPTKGSANSAGYDLYAAAECIVPRRGKVLVDTDLAIAVPEGTYGRVAPRSGLASKHSIDTGAGVIDADYRGHVRVLLFNYSDVDFPIKVGDRIAQLILERIVNPPVILVESLEATVRGANGFGSTGV