wanglab/gogpt-training-data huggingface dataset:
Protein: Long-chain-fatty-acid--CoA ligase (Q19878)
Organism: Caenorhabditis elegans
Interaction partners:
- Very long-chain fatty acid transport protein
- Long-chain-fatty-acid--CoA ligase
- BBSome complex member bbs-7
- Long-chain-fatty-acid--CoA ligase
- Phospholipid/glycerol acyltransferase domain-containing protein
- Protein pthb1 homolog
- Protein cuti-1
- BBSome complex member BBS1
- Tetratricopeptide repeat protein 8
Sequence:
MTDRANCSTSTSNWRKPKPLATDVLEKPARLLPKMKLEELVTVMLLTVAVIAQNLPIGVILAGVLILYITVVHGDFIYRSYLTLNRDLTGLALIIEVKIDLWWRLHQNKGIHELFLDIVKKNPNKPAMIDIETNTTETYAEFNAHCNRYANYFQGLGYRSGDVVALYMENSVEFVAAWMGLAKIGVVTAWINSNLKREQLVHCITASKTKAIITSVTLQNIMLDAIDQKLFDVEGIEVYSVGEPKKNSGFKNLKKKLDAQITTEPKTLDIVDFKSILCFIYTSGTTGMPKAAVMKHFRYYSIAVGAAKSFGIRPSDRMYVSMPIYHTAAGILGVGQALLGGSSCVIRKKFSASNFWRDCVKYDCTVSQYIGEICRYLLAQPVVEEESRHRMRLLVGNGLRAEIWQPFVDRFRVRIGELYGSTEGTSSLVNIDGHVGACGFLPISPLTKKMHPVRLIKVDDVTGEAIRTSDGLCIACNPGESGAMVSTIRKNNPLLQFEGYLNKKETNKKIIRDVFAKGDSCFLTGDLLHWDRLGYVYFKDRTGDTFRWKGENVSTTEVEAILHPITGLSDATVYGVEVPQREGRVGMASVVRVVSHEEDETQFVHRVGARLASSLTSYAIPQFIRICQDVEKTGTFKLVKTNLQRLGIMDAPSDSIYIYNSENRNFVPFDNDLRCKVSLGSYPF
Protein: Chromatin accessibility complex protein 1 (Zgc:110753) (Q5EAR4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEETVDQAANSRTISLPISRVRLIMKSSPDVSCINQDALFLTTKATELFVQHLALSSYENGPSKDTNTLSYSDLADTVEETETFQFLTDILPKKILARDYLKTLEEMEKEDDNM
Protein: Draxin (Dorsal inhibitory axon guidance protein) (Dorsal repulsive axon guidance protein) (B6ZI38)
Organism: Gallus gallus (Chicken)
Function: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord and cortical explants in vitro. Binds directly to the neurites and growth cones.
Subcellular location: Secreted {ECO:0000255|HAMAP-Rule:MF_03060, ECO:0000269|PubMed:19150847}.
Interaction partners:
- Neogenin
- Netrin-3
- Netrin-1
- Cell adhesion molecule DSCAM
Sequence:
MAASSTFFSPSLFLCVLVLIDITLAVSLDTDMKLKSENNNHLQNQETWPQQPRSGHHHKHGLAKKGRVLALPVRGQPAGEEALRVGSGAPAMEELVPLGQPAALKQDKDKDVFLGFELPHAERENQSPGSERGKKQNREQRRHSRRDRLKHHRGKTAVGPSSLYKKPESFEQQFQNLQAEEATSPTPTVLPFTALDLVVSTEEPPVLPATSPRSQARLRQDGDVMPTLDMALFDWTDYEDLKPEMWPSAKKKEKRRSKSSNGGNETSSAEGEPCDHHLDCLPGSCCDLREHLCKPHNRGLNNKCYDDCMCTEGLRCYAKFHRNRRVTRRKGRCVEPESANGEQGSFINV
Protein: adenylate cyclase (EC 4.6.1.1) (M9NDN7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MNKKNTYKTPYRERFRRCNLEYTNERLWEQSYLKARCKELHLEEEYMKYKIRLMISSLTVFVPMLILLIVALQVIIWSFTEYTKYIYINAIFDLGSLILVTGLLSINFFEDFVIRHRWVMTFTSTLSAYVVVLGDIAFNTYYYYKSNWPLNTLYDVFVLCMIYMFLPIPSSKAAALLAISVSLTYVIYFIHFMAFNEHNVAKYVHGLDIVSIDFFHYLGFNMMGIFFRIMNDTMVRSSFLDRYQFITEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDNDFYHLGTSRTAENFMSIQIHNDVSILYADLVNYTQLTTTLTVEKLVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAVSLGISMIANIKEVSVNRSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRLEATGSPGYVHVSGRTLSSLNAEEYNIYPGTESAQKDPVLQKHPMSTYLLTAIPSLDSDKTISIVEGVPNLDLQTVGSNRKSQILKPNLLSHEMREEFRKMPVGGFKFQFPWSRRERNLKNEKVERDLGIFCVAFKDKSVEWNYLHQPDYIFKYSVALGWGIGCCLIYIQSVNNSDIFYTGVVINIIAFFVLTFLLFICWYKKVCWWHSGQNEHRSYGKLSCAIFHLFEKIQHSFVLRLTVYMMIILCYYMVISLILMSCEKDQYELDIIESKLYNYDMDPFTCFHPWAYTNMMALILGMSYTFARIPFALKTFIGCAEAVVFVLVVCFQYAFIFEHSVTTSPYLKAEIAHSCRVCMMLITMYAKERQSEFNTKMNYKLNLDLQNKQKSADVTNQSIIILLNNILPSHVVEVYLSSIAKHELYYENYRMVSVMFAMLTNFQMDLPSLRVLNDIITAFDRLQYYVVEKIKVVGCTYMAACGLDFSLIENLDSNSNFGSTSLSSELEQVRSRLESSIKEKNHDEVAFIMATFALDLMRVLSVCNKAYAGEPFDRALSTGEIRIGISTGQIMAGVVGASQPHYDIWGNPVNMASRMESTGLSGHIQVTKETAQTLEEFDVMCYYRGLTFVKGRGEIPTYFVGIDKDLKFMSKKIDRLSENPSNPDLNHDLDGS
Protein: Neurotoxin type F (Q57236)
Organism: Clostridium botulinum
Interaction partners:
Sequence:
MPVVINSFNYNDPVNDDTILYMQIPYEEKSKKYYKAFEIMRNVWIIPERNTIGTDPSDFDPPASLENGSSAYYDPNYLTTDAEKDRYLKTTIKLFKRINSNPAGEVLLQEISYAKPYLGNEHTPINEFHPVTRTTSVNIKSSTNVKSSIILNLLVLGAGPDIFENSSYPVRKLMDSGGVYDPSNDGFGSINIVTFSPEYEYTFNDISGGYNSSTESFIADPAISLAHELIHALHGLYGARGVTYKETIKVKQAPLMIAEKPIRLEEFLTFGGQDLNIITSAMKEKIYNNLLANYEKIATRLSRVNSAPPEYDINEYKDYFQWKYGLDKNADGSYTVNENKFNEIYKKLYSFTEIDLANKFKVKCRNTYFIKYGFLKVPNLLDDDIYTVSEGFNIGNLAVNNRGQNIKLNPKIIDSIPDKGLVEKIVKFCKSVIPRKGTKAPPRLCIRVNNRELFFVASESSYNENDINTPKEIDDTTNLNNNYRNNLDEVILDYNSETIPQISNQTLNTLVQDDSYVPRYDSNGTSEIEEHNVVDLNVFFYLHAQKVPEGETNISLTSSIDTALSEESQVYTFFSSEFINTINKPVHAALFISWINQVIRDFTTEATQKSTFDKIADISLVVPYVGLALNIGNEVQKENFKEAFELLGAGILLEFVPELLIPTILVFTIKSFIGSSENKNKIIKAINNSLMERETKWKEIYSWIVSNWLTRINTQFNKRKEQMYQALQNQVDAIKTVIEYKYNNYTSDERNRLESEYNINNIREELNKKVSLAMENIERFITESSIFYLMKLINEAKVSKLREYDEGVKEYLLDYISEHRSILGNSVQELNDLVTSTLNNSIPFELSSYTNDKILILYFNKLYKKIKDNSILDMRYENNKFIDISGYGSNISINGDVYIYSTNRNQFGIYSSKPSEVNIAQNNDIIYNGRYQNFSISFWVRIPKYFNKVNLNNEYTIIDCIRNNNSGWKISLNYNKIIWTLQDTAGNNQKLVFNYTQMISISDYINKWIFVTITNNRLGNSRIYINGNLIDEKSISNLGDIHVSDNILFKIVGCNDTRYVGIRYFKVFDTELGKTEIETLYSDEPDPSILKDFWGNYLLYNKRYYLLNLLRTDKSITQNSNFLNINQQRGVYQKPNIFSNTRLYTGVEVIIRKNGSTDISNTDNFVRKNDLAYINVVDRDVEYRLYADISIAKPEKIIKLIRTSNSNNSLGQIIVMDSIGNNCTMNFQNNNGGNIGLLGFHSNNLVASSWYYNNIRKNTSSNGCFWSFISKEHGWQEN
Protein: rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1) (Q9HC36)
Organism: Homo sapiens (Human)
Function: S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282}.
Interaction partners:
- Mitochondrial assembly of ribosomal large subunit protein 1
- Large ribosomal subunit protein uL29m
- Probable ATP-dependent RNA helicase DDX28
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL11m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein uL24m
- Large ribosomal subunit protein mL43
Sequence:
MAALVRPARFVVRPLLQVVQAWDLDARRWVRALRRSPVKVVFPSGEVVEQKRAPGKQPRKAPSEASAQEQREKQPLEESASRAPSTWEESGLRYDKAYPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDKLKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDHVKMTYPKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADNCGLYAQAEMSNKASDHGWVCDQRVMKFHKYEEEEDVETGASQDWLPHVEVQSYDSDWTEAPAAVVIGGETYGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGRAEDLSRDRSYH
Protein: Opalin (Oligodendrocytic myelin paranodal and inner loop protein) (Transmembrane protein 10) (Q96PE5)
Organism: Homo sapiens (Human)
Function: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q7M750}; Single-pass type I membrane protein {ECO:0000255}. Note=In the CNS, enriched in the myelin paranodal and inner loop membranes, but not that of the PNS. Enriched in the leading edge of extending processes. {ECO:0000250|UniProtKB:Q7M750}.
Interaction partners:
- Transmembrane protein 70
- Myelin-associated glycoprotein
- Transmembrane protein 235
- Ermin
- 5-hydroxytryptamine receptor 5A
- Myelin-associated oligodendrocyte basic protein
- G protein-activated inward rectifier potassium channel 3
Sequence:
MSFSLNFTLPANTTSSPVTGGKETDCGPSLGLAAGIPLLVATALLVALLFTLIHRRRSSIEAMEESDRPCEISEIDDNPKISENPRRSPTHEKNTMGAQEAHIYVKTVAGSEEPVHDRYRPTIEMERRRGLWWLVPRLSLE
Protein: SRY-box 7 (SRY-box containing gene 7) (SRY-box transcription factor 7) (Transcription factor SOX-7) (Q6TEN5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAALISAYSSWPESFECSAGNADVPDGHTSHRAPADKVSEPRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTPPQKRPYVEEAERLRVQHMQDYPNYKYRPRRKKQLKRICKRVDPGFLLTTLGPDQNSLPDPRGCCHPLDKDDESGVSGGFGSPGAALPGVRVFRDPASSNSSFDTYPYGLPTPPEMSPLDAVDHEHQSYYSSSSSVSTSSCSSSNSCPEDRRPTPAHMSSPPPYHPDYSQQAALHSHLGHIPMSHQASGATLIAGPPLSYYSPSFPQVHIHHQGHLGQLSPPPEQGHLEGLDQLSQAELLGEVDRDEFDQYLNSTSYHPEQGGMTVTGHIQVTPASVCSSSATETSLISVLADATAAYYNNYSIS
Protein: Poly(ADP-ribose) glycohydrolase 1 (EC 3.2.1.143) (Poly ADP-ribose metabolism enzyme 3) (Q867X0)
Organism: Caenorhabditis elegans
Function: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:17188026}.
Interaction partners:
- Poly [ADP-ribose] polymerase 1
- Poly [ADP-ribose] polymerase 2
- RNA
- Poly [ADP-ribose] polymerase tankyrase
- F-BAR domain-containing protein
Sequence:
MSKKFIELGDPVTQDEKDYEDYVGVGFAHQVPTMKRRKLTEHGNTTESKEDPEEPKSRDVFVSSQSSDESQEDSAENPEIAKEVSENCENLTETLKISNIESLDNVTERSEHTLDNHKSTEPMEEDVNNKSNIDVAINSDEDDELVLEENNKEMRDGEQVQQDLFADDQELIEYPGIMKDTTTQLDITDSEVETAQKMEMIEETEADSTFVGEDSKNQRQSGTTSDEVDADSQINLATKTVRTSSSSFLSTVSTCEAPAKGRARMYQKELEKHVIAFTEGNLTLQPDLNKVDPDRNYRYCTIPNFPASQGKLREDNRYGPKIVLPQRWREFDSRGRRRDSYFYFKRKLDGYLKCYKTTGYFMFVGLLHNMWEFDPDITYKLPALEMYYKEMSELVGREEVLEKFARVARIAKTAEDILPERIYRLVGDVESATLSHKQCAALVARMFFARPDSPFSFCRILSSDKSICVEKLKFLFTYFDKMSMDPPDGAVSFRLTKMDKDTFNEEWKDKKLRSLPEVEFFDEMLIEDTALCTQVDFANEHLGGGVLNHGSVQEEIRFLMCPEMMVGMLLCEKMKQLEAISIVGAYVFSSYTGYGHTLKWAELQPNHSRQNTNEFRDRFGRLRVETIAIDAILFKGSKLDCQTEQLNKANIIREMKKASIGFMSQGPKFTNIPIVTGWWGCGAFNGDKPLKFIIQVIAAGVADRPLHFCSFGEPELAAKCKKIIERMKQKDVTLGMLFSMINNTGLPHKHFEFYVFDRISTYLSSSEDVESSKSSPSVSRA
Protein: Beta-defensin 130A (Beta-defensin 130) (Beta-defensin 30) (DEFB-30) (Defensin, beta 130) (P0DP74)
Organism: Homo sapiens (Human)
Function: Antimicrobial host-defense peptide. Has an antiplasmodial activity.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Beta-defensin 125
- Beta-defensin 135
- Defensin beta 118
- Beta-defensin 131A
Sequence:
MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCCRRWWILEPYPTPVPKGKSP
Protein: WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin) (Q8CGF6)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22523538}. Note=Localization along microtubules is mediated by MAP1S.
Interaction partners:
- Calmodulin-regulated spectrin-associated protein 3
Sequence:
MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPERSDTPVEAQQPVSSEAMCQGSGLEKEPANGAQNPVPAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQMYQQMLLEGGVNQEDGPDQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCSGSKNNGSNNSSVTSFSTPPQDSSQRLIHDTANIHTSTPRNPGSTNHIPFHEDSPCGSQNSSEHSVIKPSPGDSSGNLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG
Protein: Angiopoietin-1 (Q90Z19)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MWWGCLFLAALLVVADCGGVEQKTDGLWSSTPKSNSSSGRRYHRIQHGQCSYTFILPESDGNTCREFKSGTAYNANALQRDAPQPEADLSNQKIQQLEHVMENYTQWLQKIENYIKDNMKTEMVQLQQSAVHNHTAAMLEMGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTNKLEKQLMIQINEINKIHDKNGFLEEKMQELEDRHRQELESLRTEKSDLQALVSRQSSVIRELENQLSRATGNSTALQRQQQDLMESMRSLLSLCAKDAATAVEPNSTKQADEERKFRDCADLYQAGFQKNGVYTINISPQETKKVYCVMESAGGGWTVIQKREDGTVDFQKTWKEYKMGFGSVSGEHWLGNEFVHVLTNQRQHGLRVELSDWDGHQAFSQYDSFHIDSEKQKYRLFLKTHSGTAGRQSSLAVHGADFSTKDVDNDNCTCKCALMLSGGWWYDACGPSNLNGVYYRQGQHVGKFNGIKWHYFKGPSYSLRSTVMMIRGADFS
Protein: Cullin 4B (D3ZK73)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- E3 ubiquitin-protein ligase RBX1
- DNA damage-binding protein 1
- DDB1- and CUL4-associated factor 1
- Cullin-4A
- Protein cereblon
- Denticleless protein homolog
- DDB1- and CUL4-associated factor 11
- DNA damage-binding protein 2
- Cullin-associated NEDD8-dissociated protein 1
- DET1 partner of COP1 E3 ubiquitin ligase
Sequence:
MSRSTKSRERRENDANSEDNSSETSNQERRRCLQGPPRPPYPPLLPPVFPPPTPPPQVRRTRGLQDLGAMKSVCPGTSGFSSPNPSAASAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSSNSSNEREDFDSTSSSSTPPQPRDSASPSTSSFCLGVPVATSSHVPIQKKLRFEDTLEFVGFDTKMAEESSSSSSSSSPTAATSQQQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQTKTIDGILLLIERERNGEAIDRSLLRSLLNMLSDLQIYQDSFEQRFLQETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIASVEKQLLGEHLTAILQKGLNSLLDENRIQDLSLLYQLFSRVRGGVQVLLQHWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDTCFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA
Protein: Leucine-rich repeat and fibronectin type-III domain-containing protein 2 (Q460M5)
Organism: Rattus norvegicus (Rat)
Function: Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of GRIN1 and GRIN2A NMDA receptor subunits. May play a role in redistributing DLG4 to the cell periphery (By similarity).
Subcellular location: Membrane {ECO:0000269|PubMed:16495444}; Single-pass type I membrane protein {ECO:0000269|PubMed:16495444}. Synapse {ECO:0000269|PubMed:16495444}. Postsynaptic cell membrane {ECO:0000269|PubMed:16495444}.
Interaction partners:
- Disks large homolog 4
- Disks large homolog 3
- Disks large homolog 1
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2A
- Glutamate receptor ionotropic, NMDA 2B
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L1
- Adhesion G protein-coupled receptor L2
- Glutamate receptor ionotropic, NMDA 2C
Sequence:
METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLKTCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDAPGKMAAATVSNVYSQTNGAQPPPLGGMPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEENDLVGARGTFGSSEWVMESTV
Protein: Mite group 2 allergen Der p 2 (Allergen Der p II) (DPX) (allergen Der p 2) (P49278)
Organism: Dermatophagoides pteronyssinus (European house dust mite)
Subcellular location: Secreted.
Interaction partners:
Sequence:
MMYKILCLSLLVAAVARDQVDVKDCANHEIKKVLVPGCHGSEPCIIHRGKPFQLEAVFEANQNTKTAKIEIKASIDGLEVDVPGIDPNACHYMKCPLVKGQQYDIKYTWNVPKIAPKSENVVVTVKVMGDDGVLACAIATHAKIRD
Protein: Beclin-1-like protein (AtBECLIN 1) (Autophagy protein 6) (AtATG6) (Protein VPS30 homolog) (AtVPS30) (Q9M367)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for normal plant development. Required for pollen germination. Required for autophagic activity. Required to limit the pathogen-associated cell death response. May be involved in vacuolar protein sorting. Binds to microtubules. May facilitate efficient recruitment of other ATG proteins to assemble scaffolds for autophagosome biogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17259285}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:26566764}. Note=Colocalizes with ATG8I in punctuate structures (PubMed:17259285). Localizes in punctuate structures and colocalizes with microtubules (PubMed:26566764). {ECO:0000269|PubMed:17259285, ECO:0000269|PubMed:26566764}.
Interaction partners:
- Phosphatidylinositol 3-kinase VPS34
- Serine/threonine-protein kinase VPS15
- Autophagy-related protein 11
- Autophagy-related protein 3
- Autophagy-related protein 16
- Autophagy-related protein 9
- Serine/threonine-protein kinase ATG1b
- Serine/threonine-protein kinase ATG1c
- Autophagy-related protein 101
- Autophagy protein 5
Sequence:
MRKEEIPDKSRTIPIDPNLPKWVCQNCHHSLTIVGVDSYAGKFFNDPPPSATQGSSIHGANSVLGSTRMDNSFVVLPRHKPPQSQGIPPRPRGASSPQPDATQSGKAMEESFVVVYKSEPVSDSGGSHNLSLEVGQNGPLHSNTSGFNATINVLTRAFDIARTQTQVEQPLCLECMRVLSDKLEKEVEDVTRDVEAYEACVQRLEGETQDVLSEADFLKEKKKIEEEERKLVAAIEETEKQNAEVNHQLKELEFKGNRFNELEDRYWQEFNNFQFQLIAHQEERDAILAKIEVSQAHLELLNKTNVLIDAFPIRNDGEFGTINNFRLGRLPAIKVEWDEINAAWGQACLLLHTMCNYFRPKFQCQVKIQPMGSYPRIVDSNNETYELFGPVNLFWSTRYDKAMTLYLMCLKDFADFANSKDQENNIPPDNCLNLPYKIEKDKVLGYSITQSFNKQESWTKALKYTLCNLKWALYWFVGNTNFQPLSATVSLPSNISAAGSLYAKRGPDSSKPSCKKT
Protein: Uncharacterized protein (Q57VZ8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MADSNNSGCDAAVAGAHNNNNNNNEEEFLPDAVAGSSAIKAPVPRKRVVKIGTSSQLLQEELGFPKESSKRKDDAADPAGDGSPEGFLDSGTVDPFMTVIYPNTGTEKDEDGLDDDEEADIANRVVSRRDGDNFDRTQVRVGGFLQGADDNMAFLIPNDLPRSTFLYLLTASDGRDRLFKCMQCSLHLLICLLMRPSILPQGSEETADYWAERFRKNINTIRHGRSLFKLGRWIVNAFYLQEVYERLALKYGRTMREVKGEFKAFLCRYLSLPPGSVMRRLIGWDNNGVGGGSAGQFVNREVLVPGDTYEHVARVEFPRQFVSELHSIDAKLVTTGPSLTGIQQKEVGVSGAIKASDMALQSEEAKEDGDRKVAGFSTLSEGKGLMVRDPLRTEALTSGSLAPSATPPSLYPAATEMYAVGIGNTTRASLSKPATLLRPLRCTGADDESSNSNNTSIAHNNNTAPSSICGGSLNYSLMQEGKPKGDTYNEGFSTSRNPDDSHQSYFKMYQTVPYEPKLGDALRLPHQGEGDSMNKMSKNQPSRAKFARCGSAVDNGDDIGAEENMFSLGAAFDEGDNHLESNGTVSPSDDREEERERGLAAEMGKPASRRKGILQFSTPLILLQAVRSIATIARRLLRDLLLLSSEHFLNLSPVEKNRALLQRHCHWLWLIVASIDVLLNTIRLLNPGWYKYTNVRDNPRFRCGCKDPDTRGSVMLFRELVIRRQANLYFPDVDLDFGVPICSSPGYFEAADPENIAPACRVCGKLFVEMTSPDEQGEKLEEGGDDTTAEEKGVTDTEEVETNGNAAVRQKASKSITGRAEVVFLFIPWLMRRLFNYIWLVRSHSNWSATIWLQVSYLAEFYLAVMYCFGGYDTGKRDAPLKAMIHPTGAIVGFVGAIIGVYRVIQSAPK
Protein: Acyl-CoA desaturase 3 (EC 1.14.19.-) (Delta(9)-desaturase 3) (Delta-9 desaturase 3) (Fatty acid desaturase 3) (Palmitoyl-CoA desaturase) (Stearoyl-CoA desaturase 3) (Q99PL7)
Organism: Mus musculus (Mouse)
Function: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA. Has a strong preference for saturated fatty acids with chain lengths of 14 or 16 carbon atoms (C14:0 and C16:0), and has only very low activity with stearatate (C18:0). Required for the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O00767}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O00767}. Microsome membrane {ECO:0000269|PubMed:16443825}.
Interaction partners:
Sequence:
MPGHLLQEEMTPSYTTTTTITAPPSGSLQNGREKVKTVPLYLEEDIRPEMKEDIYDPTYQDEEGPPPKLEYVWRNIILMALLHVGALYGITLVPSCKLYTCLFAFVYYVISIEGIGAGVHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGILLMCFILPTLVPWYCWGETFLNSFYVATLLRYAVVLNATWLVNSAAHLYGYRPYDKNIDPRQNALVSLGSMGEGFHNYHHAFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKRVSKATVLARIKRTGDGSHKSG
Protein: Na+/H+ antiporter subunit C (Q9I4R9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Probable NADH dehydrogenase
- Na+/H+ antiporter subunit E
- Probable NADH dehydrogenase
- Na+/H+ antiporter subunit G
- K+/H+ antiporter subunit F
- NADH-quinone oxidoreductase subunit L
- NADH-quinone oxidoreductase subunit C/D
Sequence:
MEALFAITLGLLTASGVYLLLRARTFPVVLGLTLISYAVNLFLFAMGRLGGSVAVIGTPGEYGDPLPQALVLTAIVIGFAMTAFVVVLALRGLGDLGSDHVDGRPDEEEPRP
Protein: Short transient receptor potential channel 1 (Q9PRI8)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Transient receptor potential cation channel subfamily V member 4
- Transient receptor potential cation channel subfamily V member 4
- Polycystin-2
- Uncharacterized protein.
- SAM domain-containing protein.
- Uncharacterized protein.
- Transient receptor potential cation channel subfamily M member 4 isoform X2
- Transient receptor potential cation channel subfamily A member 1
- Uncharacterized protein.
- SOAR domain-containing protein.
Sequence:
MAALYQSTDSSSPNTFLALKDVREVKEETTLDERLFLLACEKGDYYMVKKLLEENSSEELNINSLDILGRNAITISIENENLDILQLLLNYGFQSTDALLVAIDSEVVGAVDILLNHQPKWTTRPSIVKLMEQIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCTAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAQKCKTFAKDLLAQARNSRELEVILNHQSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMAAYRRKHTCKKILIVLTVGIFWPVLSMCYLLAPKSQVGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDEKNTMGPALERIDFLLIIWLIGMVWSDVKQLWYDGLEDFLKESQNQLSFVMNSLYLATFALKVVAHNKFHSIAERKDWDAFHPTLVVEGLFAFGNVLSYLRLFFMYTTSSILGPLQIFMGQMLQDFGKFLGMFLLVLFSFTIGLTHLYEKGYTTNEQKDCVGIFCEQQSNNTFHSFTGTCYALFWYIFSLAHVTLFVTRFNFSEELQSIVGALIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIVPSPKTICYLFNSISKWICSHTTSGRVKRQNSFKEWKSLRQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELCQDLSKFRNEMRDLLGFRTSKYAMFYPRN
Protein: Sclerostin domain-containing protein 1 (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1) (Q6X4U4)
Organism: Homo sapiens (Human)
Function: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
Subcellular location: Secreted {ECO:0000269|PubMed:15020244}.
Interaction partners:
- Low-density lipoprotein receptor-related protein 5
- Bone morphogenetic protein 4
- Bone morphogenetic protein 7
Sequence:
MLPPAIHFYLLPLACILMKSCLAFKNDATEILYSHVVKPVPAHPSSNSTLNQARNGGRHFSNTGLDRNTRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESMSPAKPVQHHRERKRASKSSKHSMS
Protein: Syntabulin (A0A0C4DG86)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MGPLRESKMSNFEKEHRVQHHDKEISRSRIPRLILRPHMPQQQHKVSPASESPFSEEESREFNPSSSGRSARTVSSNSFCSDDTGCPSSQSVSPVKTPSDAGNSPIGFCPGSDEGFTRKKCTIGMVGEGSIQSSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGASSHKPGSSPSSPREKDLLSMLCRNQLSPVNIHPSYAPSSPSSSNSGSYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLHERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADGLSLEEQVTGEGADRELLVGDSIANSTDLFDEIVTATTTESGDLELVHSTPGANVLELLPIVMGQEEGSVVVERAVQTDVVPYSPAISELIQSVLQKLQDPCPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLSPVETPYANVDAEVHANRLMRELDFAACVEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWAFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT