wanglab/gogpt-training-data huggingface dataset:
Protein: FCS-Like Zinc finger 14 (Q8GYX2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:29945970}. Nucleus {ECO:0000269|PubMed:29945970}.
Interaction partners:
- FCS-Like Zinc finger 16
- At1g68440/T2E12_1
- At4g35750
- Polyketide cyclase/dehydrase and lipid transport superfamily protein
Sequence:
MLTKRTHPMIGKISELLVGVNRSTAAPFFDVLMTSPKSPLDFKILPQISQRNSSKRFYDDNLGGSVGLGIVAALENSNTRRITSVCRSEPNQPGRSDPVQFMSHGGSTDGEDEEMFIMDEEDYTLVTCHHGPSGSCNTRVYDKDGFECFSSKINDDRRERLFVVDVVTESPENSPEFQGLGFLNSCYLCRKKLHGQDIFIYRGEKAFCSTECRSSHIANDERKERCRSKFSTSPYTAGQIFSTGVLVT
Protein: Protein TIFY 6B (Jasmonate ZIM domain-containing protein 3) (Protein JASMONATE INSENSITIVE 3) (Q9LVI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY6B/JAZ3 interaction. Acts as a negative regulator of MYC2 function. Feed-back regulated by MYC2.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:19151223}.
Interaction partners:
- Transcription factor MYC2
- Coronatine-insensitive protein 1
- Protein TIFY 9
- Transcription factor MYC4
- AFP homolog 2
- Protein TIFY 11B
- Transcription factor MYC3
- Protein TIFY 3A
- Protein TIFY 11A
- Protein TIFY 5B
Sequence:
MERDFLGLGSKNSPITVKEETSESSRDSAPNRGMNWSFSNKVSASSSQFLSFRPTQEDRHRKSGNYHLPHSGSFMPSSVADVYDSTRKAPYSSVQGVRMFPNSNQHEETNAVSMSMPGFQSHHYAPGGRSFMNNNNNSQPLVGVPIMAPPISILPPPGSIVGTTDIRSSSKPIGSPAQLTIFYAGSVCVYDDISPEKAKAIMLLAGNGSSMPQVFSPPQTHQQVVHHTRASVDSSAMPPSFMPTISYLSPEAGSSTNGLGATKATRGLTSTYHNNQANGSNINCPVPVSCSTNVMAPTVALPLARKASLARFLEKRKERVTSVSPYCLDKKSSTDCRRSMSECISSSLSSAT
Protein: Protein K7 (F5HDA4)
Organism: Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Function: Plays a role in the inhibition of host apoptosis to allow completion of the viral lytic replication and may thus favor the maintenance of persistent infection in infected host.
Subcellular location: Host membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Host mitochondrion {ECO:0000269|PubMed:12388711}.
Interaction partners:
Sequence:
MGTLEIKGASLSQFSTGTAQSPWLPLHLWILCSLLAFLPLLVFIGAADCGLIASLLAIYPSWLSARFSVLLFPHWPESCSTKNTARSGALHKPAEQKLRFAQKPCHGNYTVTPCGLLHWIQSPGQL
Protein: Nucleolin (F1R6L6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MVKLAKAAKKDAPPKKKAPPPPKEVEEESSEEDSDDDEEEEAPPVKAVAKKNAAPVKAVKNGKAAAKQESEDEDDDDEDDESEEEAPPPKKAAKAPAKAAAPAKKAAPAEESSEEDDDDDDDDESEEEAPPPKKAPAKATPAKATPAKKAAPVKKAAPAEESEDDDDDEDESEEEEAPPPKKAAAAAKPAAKAPAAKEESDEEEDDDEEEDDSEEEEMDTTPAPKAKKAGMVKAKEESEEEDDDDEEDDDDEEEEETPATPAKRKAETKKEKGTPPAKKAKTDGEGFSLFLGNLNNNKDFDELKSAISKFFSKEGLEIQDVRLGGTKKFGYVDFASEEELQKALELNGKKLLGQPVKLDKARSKENSQENKKERDARTLFVKNLPYSITQDDLREIFDQAVDIRVPMGNTGTSRGIAYIEFKTEAIAEKALEEAQGSDVQGRSIIVDFTGDKSRQGGRGAPSASKVLVVNNLAFSASEDSLQSVFEKAVSIRIPQNNGRPKGYAFVEFENVEDSKEALENCNNTDIEGRSIRLEYSQNDRERGGGGRGNSGPTKTLFVKGLSDDTTDQTLKDSFDGAIAARIATDRDTGSSKGFGFVDFDNEQDCKAAKEAMDDGEIDGNKVTLDYAKPKGEGGRGGFGGGRGGFGGRGGGRGGFGGRGGGGRGGGFRGGRGGRGGGGGFRGGRGGGGRGGFGDRPQGKKIKFDD
Protein: ABSCISIC ACID-INSENSITIVE 5-like protein 5 (ABA-responsive element-binding protein 1) (Abscisic acid responsive elements-binding factor 2) (ABRE-binding factor 2) (bZIP transcription factor 36) (AtbZIP36) (Q9M7Q4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in ABA and stress responses and acts as a positive component of glucose signal transduction. Functions as transcriptional activator in the ABA-inducible expression of rd29B. Binds specifically to the ABA-responsive element (ABRE) of the rd29B gene promoter.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:15516505, ECO:0000269|PubMed:16284313}.
Interaction partners:
- Serine/threonine-protein kinase SRK2E
- Serine/threonine-protein kinase SRK2D
- Dehydration-responsive element-binding protein 1A
- NAC domain-containing protein 96
- Dehydration-responsive element-binding protein 2A
- Serine/threonine-protein kinase SRK2I
- Dehydration-responsive element-binding protein 2C
- Protein phosphatase 2C 56
- Basic leucine zipper 8
- Low-temperature-induced 65 kDa protein
Sequence:
MDGSMNLGNEPPGDGGGGGGLTRQGSIYSLTFDEFQSSVGKDFGSMNMDELLKNIWSAEETQAMASGVVPVLGGGQEGLQLQRQGSLTLPRTLSQKTVDQVWKDLSKVGSSGVGGSNLSQVAQAQSQSQSQRQQTLGEVTLEEFLVRAGVVREEAQVAARAQIAENNKGGYFGNDANTGFSVEFQQPSPRVVAAGVMGNLGAETANSLQVQGSSLPLNVNGARTTYQQSQQQQPIMPKQPGFGYGTQMGQLNSPGIRGGGLVGLGDQSLTNNVGFVQGASAAIPGALGVGAVSPVTPLSSEGIGKSNGDSSSLSPSPYMFNGGVRGRKSGTVEKVVERRQRRMIKNRESAARSRARKQAYTVELEAEVAKLKEENDELQRKQARIMEMQKNQETEMRNLLQGGPKKKLRRTESGPW
Protein: Radial spoke head protein 9 homolog (Q9H1X1)
Organism: Homo sapiens (Human)
Function: Component of the axonemal radial spoke head which plays an important role in ciliary motility. Essential for both the radial spoke head assembly and the central pair microtubule stability in ependymal motile cilia (By similarity). Required for motility of olfactory and neural cilia and for the structural integrity of ciliary axonemes in both 9+0 and 9+2 motile cilia (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9D9V4}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9D9V4}. Cell projection, kinocilium {ECO:0000250|UniProtKB:Q5TYW6}.
Interaction partners:
- Radial spoke head protein 4 homolog A
- Radial spoke head protein 6 homolog A
- Radial spoke head 1 homolog
- Dynein axonemal intermediate chain 2
- Dynein axonemal intermediate chain 1
- Dynein axonemal heavy chain 5
- Dynein axonemal assembly factor 1
- Protein kintoun
- Dynein axonemal heavy chain 11
- Thioredoxin domain-containing protein 3
Sequence:
MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIAQGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVNEGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSEAKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLRSLLWPGLTFYHAPRTKNYGYVYVGTGEKNMDLPFML
Protein: Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) (NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase) (NAD(P)H-dependent dihydroxyacetone-phosphate reductase) (Q97NF1)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00394}.
Interaction partners:
Sequence:
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
Protein: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) (Q9U1Y0)
Organism: Caenorhabditis elegans
Interaction partners:
- Alkyl transferase
- AlkylGuanine DNA alkylTransferase
- Tyrosine-protein kinase
- DNA polymerase kappa
- Nucleotide-diphospho-sugar transferase domain-containing protein
- Uracil-DNA glycosylase
- Endonuclease III homolog
- DNA polymerase
- Double-strand break repair protein mre-11
- Large ribosomal subunit protein mL62
Sequence:
MIIRECVYEVVETDQGQALIAECVGSQKVVAIYLLDDDLDDQMEELHDAYPTVNFIPGKPTQSSGIVQALNTLDSTIKVNAVHKGDTAFGMQVYSAIQKIPKGETRSYSDIAREIGNPSAVRAVASACARNNLAYIVPCHRVIGSTGNLSGYRWGIAKKRRLLQAEGAELRFSVM
Protein: Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein) (O35602)
Organism: Mus musculus (Mouse)
Function: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter (By similarity).
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKEDGILDTFPAERSSRSSKERDPRLGAQPACPKAPAGGSESSPPAAPGFVPEYEATRPCYPKEQGEARPSPGLSVGPAAGDSKLSEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSSALAPLGTGPGSGSGPPGSALPLEPWLGPPLPGGGATALQSLPGFGPPGQGLPASYTPPPPFLNSAPLGPGLQQLGPPPAYPCAPAFGDKFSLEEAYPRNSSIAALRLKAKEHIQAIGKPWQAL
Protein: Anion transporter SULP-4 (STAS domain-containing protein) (G5EEA7)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- LSDAT_euk domain-containing protein
Sequence:
MAPPGRINHARHLSEAEEEAENYLEHFYNKSEPNKRRVSFVQRGAMNQAQFDEKFDYNKPHLENELKKQAKKFVRRFYEPFTSFFALKLFIFDLIPILKWFPEYKWKTDLSLDIIGGITVGVMQVPQGIAYALLAKQPAINGLYTSLFPPLIYMLFGTSRHASLGTFAVVSLMTGLSVEKLAAPTDYDPSSFNETDIDLVKLPSPTEVSCAITITMGLILFVMGVLRLQFLTTYLSDQVIAGFTVGSSVHVLVSQLKTLLGIRGLPRHSGPFYLFRHLYDLVMSITRANPVSCGISIVSIIVLHFGKEFINPFIKRKTKSNIPIPWELVIVILSTVFVAVTGVDTEAKVQVVNKIPVGVPNFSLPSFYLIPQVLPDAISITVVSISVWLSISKMLAKRYNYELDSGQELFALSFASISSSFIPSIPNSCSLSRTLVAVGAGCTTQLSIFFSSLIVFSVVIFLGTLLETLPMAALSAIICVALQGMFRKFADLIDLWKVSKIDFTIWVVSCVSTILLDVSTGLIISVCFALFTTILREQYPKWHLLASVKGTQDFRDAERYGETVYFKGICIFRFDAPLLFHNVECFKKSIEKAYTEWQKSHEFYVLREERETILNTKLDGSDESIDGKMFQTAQSTLNTHSPDILSRHFVIDCSGFTFIDLMGVSALKEIFSDMRKRGILVYFANAKAPVREMFEKCHFFNFVSKENFYPTMRDATSIARQRQLELGFKDTGYVPEHDRLTEVLSSHPM
Protein: Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4) (Q5GLZ8)
Organism: Homo sapiens (Human)
Function: Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:15676274}. Note=shows a punctate cytoplasmic distribution.
Interaction partners:
Sequence:
MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
Protein: Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (AtCPSF100) (CPSF 100 kDa subunit) (Protein EMBRYO DEFECTIVE 1265) (Protein ENHANCED SILENCING PHENOTYPE 5) (Q9LKF9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Required for antisense-RNA-mediated gene silencing.
Subcellular location: Nucleus {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:19573236}. Note=Localized in the cytoplasm when associated with CPSF30. {ECO:0000269|PubMed:19573236}.
Interaction partners:
- Flowering time control protein FY
- Cleavage stimulation factor subunit 50
- HEAT repeat-containing protein
- Cleavage and polyadenylation specificity factor subunit 3-I
- Cleavage and polyadenylation specificity factor subunit 1
- Nuclear poly
- FIP1[V]-like protein
- Symplekin
- Cleavage stimulating factor 64
- 30-kDa cleavage and polyadenylation specificity factor 30
Sequence:
MGTSVQVTPLCGVYNENPLSYLVSIDGFNFLIDCGWNDLFDTSLLEPLSRVASTIDAVLLSHPDTLHIGALPYAMKQLGLSAPVYATEPVHRLGLLTMYDQFLSRKQVSDFDLFTLDDIDSAFQNVIRLTYSQNYHLSGKGEGIVIAPHVAGHMLGGSIWRITKDGEDVIYAVDYNHRKERHLNGTVLQSFVRPAVLITDAYHALYTNQTARQQRDKEFLDTISKHLEVGGNVLLPVDTAGRVLELLLILEQHWSQRGFSFPIYFLTYVSSSTIDYVKSFLEWMSDSISKSFETSRDNAFLLRHVTLLINKTDLDNAPPGPKVVLASMASLEAGFAREIFVEWANDPRNLVLFTETGQFGTLARMLQSAPPPKFVKVTMSKRVPLAGEELIAYEEEQNRLKREEALRASLVKEEETKASHGSDDNSSEPMIIDTKTTHDVIGSHGPAYKDILIDGFVPPSSSVAPMFPYYDNTSEWDDFGEIINPDDYVIKDEDMDRGAMHNGGDVDGRLDEATASLMLDTRPSKVMSNELIVTVSCSLVKMDYEGRSDGRSIKSMIAHVSPLKLVLVHAIAEATEHLKQHCLNNICPHVYAPQIEETVDVTSDLCAYKVQLSEKLMSNVIFKKLGDSEVAWVDSEVGKTERDMRSLLPMPGAASPHKPVLVGDLKIADFKQFLSSKGVQVEFAGGGALRCGEYVTLRKVGPTGQKGGASGPQQILIEGPLCEDYYKIRDYLYSQFYLL
Protein: p81 (Q80IX5)
Organism: Providence virus (isolate Helicoverpa zea/United States/vFLM1/-) (PRVFL)
Subcellular location: Virion {ECO:0000256|ARBA:ARBA00004328}.
Interaction partners:
Sequence:
MQNLPVPNGESPPKTDEVRDSRRNSDDEEPEYPRGDPIEDLTDDGDIEKNPGPASANQAGKRLEPRKRTRSIRSRQDLDTMHRVVVSVDVDSLTTLMGNIMTLAGSGGRGSLLTAGDVEKNPGPQMTRENKAPNMSVRAQNVTVSNSRRRRRKNRKPRKQVEQATILKPQLLPGESVAPSGGRGTMDPPVHEICAQSIDPSEGAVGWFYKYMDPAGAVESGKALGEFSKVPDGLLRYSVDAEQRPIVTIECPTVSESDLPLDGKLWRVSFISFPAFRLNFIALANINNEALTLETRNTFIQTLNNITNWRDLGTGQWAQFAPGWYYSIYVLPNTYAMAEIGDRTDSVTQFRKVYKGITFEFNAPTLIDQGWWVGAHIPVKPQSETIPAAERFSAGSMTVSASNAIFQPSNTVARIVWSITPLPVATVALTTGTGGTNNTSGKFFSVEIDGNVNSVWTFTAPASILAEGEPFAEEGDTTSFSMTTITADTVVYSVSSSLTGSSVIVRGVTKGSGVSITPVTVGIDTEAVNRLSIEMPALTTEEVTTNVPKYEQFLCKESGGAYIVHYKMNNPVFEMTGEENFGGFQFHYPGYDPENNALGLRGIVDTFENNFSSAVVHFWGISQSATIVCKTYDGWEGTTNAGSTVGQFAHTGAEEEDEVVQLANRLQMELTGVYQADDNFAGTVSALASIGLGLLGKSSATPSVIKGIAQQAVGAVQANPGILEGAVKAIGSVGARLVGSIKARRARRRARRAK
Protein: Nuclear receptor coactivator 2 (NCoA-2) (NCoA2) (Glucocorticoid receptor-interacting protein 1) (Steroid receptor coactivator 2) (Transcriptional intermediary factor 2) (Q98TW1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) (By similarity). Has a role in primitive myelopoiesis in the differentiation of granulocytes and macrophages. May play a role in the positive regulation of the circadian clock (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q15596}.
Interaction partners:
- Histone acetyltransferase
- Androgen receptor
- Retinoic acid receptor RXR-alpha-A
- Nuclear receptor coactivator 1.
- Glucocorticoid receptor
- Histone-arginine methyltransferase CARM1
- Protein kinase N1a.
- Nuclear receptor subfamily 1, group H, member 3
- Estrogen receptor
- histone acetyltransferase
Sequence:
MSAVGENSSDPARSEAQKRKEGPSDLLGPSPKRSTEKRNREHESKYIEELAELIFANFNDIDNFNVKPDKCAILKETVKQIRQIKEQEKAAAANEDEVQKADVSSTGQSVIDKDALGPMMLEALDGFFFVVNMEGNIVFVSENVTQYLRYNQEELMNTSVYSILHVGDHAEFIKNLLPKSHVNGVPWSSENPRRNSHTFNCRMLVNPHSEAEETQDHEAQQKYETMQCFAVSEPKSIKEEGEDFQSCLICVARRVPMKERPMLPTQESFTTRQDLQGKITSLDTSLLRASMKPGWEDLVRRCIQRFHLQNDGDISFAKRHQQEVIRHGQAFSPIYRFSLSDGTIVSAHTKSKLVRSSSTNEPQLYMSLHILQREQPVCGMASDLGNAQTMGKPMNPMSSPNTAGSSCTPQGQDATISSNTSTFPSPGAQKEPGAMHRFGCPGTMSHSATMQAATPQGSGYPLKLSSPSQGSPGMLSPRHRASPGVAGSPRLPPPQFSPAGSLHSPASMCTSSTGGNGGAGANHGYTSSSLNALQALSECHGVSHGQSLGSPDRKLGSPAAHSVAVSHHLINKMSVPESFGEQNQSEQGTPGQDEGIDLPRDEKGNLGQFGNLDGSDPQSRLRDNKSHTKLLQLLTTKTEPIESTSPPPMAGGEPGCKDGGAGNGGMGSQGGNGSHATSLKEKHKILHRLLQNSSSPVDLAKLTAEATGKELCQDSAGGTAGVPELAIKQEPVSPKKKDNALLRYLLDKDDNVLKGKGIKMEPGEIKEEGGKMTGIKTEKTDGGYDRVEPSSELDDILDDLQNSQPGLFTDSRPVSLPSAVDKQSIINDILQMTGESGANMSPQQQRALQTAVSQQNFPAPRPGQPGRAPPVRSVSLDMNMPPKGAQGQYPMMRNNNPYSIMQQQGMMGNHAVMPNQPNMVNAGVMGNNGPRVGMQQDGWGAQGTVGSAASPATAAPAGQHSLPQGALHSRMVPNPATGMPMRPNSQPGPRPMLQPQMMANAQSNMDMGMAGHQFPQQQAPPNQTAPWPDSVMPIEPVPFGNQSSSMYGGSQEDVLCPPASEGPADEGALLSQLYSALKDFDGLEEIDRALGIPALVGQAQPVEQDQFPGQDPSMMMDQKPPMYGQQQYASSPANMQQAGYTPMQDATFHGLQGQMGQRPGYPMLRMQARPGLRPGGVVPNQPNTLRLQLQHRLQAQQNRQPMMNQMGGVSNMNLPLRPNVPNQGTINAQMLAQRQRELLSNHLRQRQLDQQRQQQQQQQQQRSLAMRAQGLTMPPNMAAAAAGMPGAMSNPRIPQANLQQFPYPPNYGTGLASPPPSTSPFSPGSPNLPAPQLLSHSAMHGSQMSLANQGMLGSLSGQFGAVMSPQMQHSAFQFPSSGMSQQSDGGFGGAATPQSPLMSPRMGHAQSPMMQQAQGNSSFQSSPDMNGWPQGNINTNSMFTQQSPPQFSQQANNNMYNGNGMNLNVSMAANSSNMGQMGNQMSMSSMNSGPGSGMANMGPEQQKYC
Protein: Cytochrome f (P0C388)
Organism: Oryza sativa subsp. indica (Rice)
Function: Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Photosystem I reaction center subunit II
- Cytochrome b6-f complex subunit 4
- Cytochrome b6
- Photosystem II CP47 reaction center protein
- Cytochrome b6-f complex subunit 5
- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic
- DUF1618 domain-containing protein
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- DUF1618 domain-containing protein
- DUF1618 domain-containing protein
Sequence:
MENRNTFSWVKEQMTRSISVSIMIYVITRTSISNAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVLRIPYDMQLKQVLANGKKGGLNVGAVLILPEGFELAPPDRISPELKEKIGNLSFQSYRPNKKNILVIGPVPGKKYSEIVFPILSPDPAMKKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATSTGVVRKILRKEKGGYEISIVDASDGRQVIDLIPPGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFFASVILAQVFLVLKKKQFEKVQLYEMNF
Protein: Uncharacterized protein C607.07c (Q9US11)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:16823372}; Single-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MGTFGIVALSIICSIAFLFVAYGVLRLINSIRRRNMMTADVSSVKSSQTWNFLKNPFSNSAKFEALDADDMWDTRVEEAELNTIPSASPFIDHTSETVPFVNTEAPPPRLSSSFSRQSGENAETQSQVSASPFNDKNSPYVQE
Protein: Ubiquitin-like modifier hub1 (O94650)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Forms a conjugate with snu66 and facilitates its localization to the nucleus. Involved in morphogenesis. Required for efficient splicing of pre-mRNA.
Subcellular location: Nucleus. Cytoplasm.
Interaction partners:
- U4/U6.U5 tri-snRNP-associated protein snu66
- Pre-mRNA-splicing factor spp42
- Uncharacterized protein C1782.03
- Pre-mRNA-splicing factor 38
- Pre-mRNA-splicing factor ini1
- Ubiquitin-like protein 1
- Small nuclear ribonucleoprotein G
- U2 snRNP component ist3
- A1 cistron-splicing factor aar2
- Pre-mRNA-splicing factor cwf5
Sequence:
MIEVLCNDRLGKKVRVKCMPDDTVGDFKKLVAAQTGTDPRRIVLKKWHSVFKDNITLADYEIHDGMSLEMYYS
Protein: Gem-associated protein 6 (Gemin-6) (Q9CX53)
Organism: Mus musculus (Mouse)
Function: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q8WXD5}. Nucleus, gem {ECO:0000250|UniProtKB:Q8WXD5}. Cytoplasm {ECO:0000250|UniProtKB:Q8WXD5}. Note=Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm (By similarity). {ECO:0000250}.
Interaction partners:
- Gem-associated protein 7
- Gem-associated protein 5
- Probable ATP-dependent RNA helicase DDX20
- Gem-associated protein 8
- Gem-associated protein 2
- Gem
- Serine-threonine kinase receptor-associated protein
- Survival motor neuron protein
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein F
Sequence:
MSEWMKKSPLEWEDYVYKEVRVIACEKEYKGWLLTTDPVSANIVLVNFLEDGRLSVTGIMGHSVQTVETISEGDHRVREKLMHVFASGDCKGYSPEDLEEKRTSLKKWLEKNHIPVTEQGDAQRTLCVAGVLTIDPPYAPENCSSSNEIILSRIQDLIQGHLSASQ
Protein: Straightjacket, isoform C (A0A0B4K866)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Voltage-dependent calcium channel type A subunit alpha-1
- Ca2+-channel-protein-beta-subunit, isoform L
- Voltage-dependent calcium channel type D subunit alpha-1
- VWFA and cache domain-containing protein CG16868
- Rad, Gem/Kir family member 2, isoform C
- Ca[2+]-channel protein alpha[[1]] subunit T, isoform F
Sequence:
MAWSRLLAWWRLCLGLLSVLVCLAPCVNLQPAENINYNLVHSWADKLGMELFHLGDFITRRKEVQESFKDAKVVSRNGASIVDSMAKEIEMMMDLKVSAVRRIMDTAENTALSHQNDMADKMFSYYSAKEMLEPGDPVPPIPTPAPDMDKDIGEPLIYVQPKVVVLEPRPEFHNTPVNFSVSSVHVPVNVFDRAPDVIKAIQWSENLDQIFRDNYKNDPTLSWQFFGSSTGFMRQFPASKWRKDVPVDLYDCRLRSWYMEAATSPKDIVILMDGSGSMLGQRLDIAKHVVNTILDTLGTNDFVNIFTFDKEVSPVVPCFEDTLIQANLGNIRELKEGIELFRPKSIANYTAALTKAFELLEETKLSSRGAQCNQAIMIIGDGAPENNREVFELHNWRDPPYKPVRVFTYLIGKEVANWDDIRWMACENQGYYVHLSDTAEVREMVLNYIPVMARPLVLGRHDHPVIWSQVYADIEDTKLSDYLWDINQCEYQKADVLEYWQVHDRMLEPSEMHRRKYRRMKETWNQPVDSNVYQFMTTVSMPIYDRRENALINLTTDINPAAKINLQVTRIANILGVAGTDVPINEIKKLLSPFTLGVNGYAFIVTNNGYVLFHPDFRPIFQGYILKPAYNSVDMIEVELLDDDRPARDFNPVLMTIRDSIINQSTGSKWMLVKNHFDEMKRVARVKRQYYWTAIKKTPFTLVISYPEQYGVSHMDIRADQEIHRISIKGTNLRSVFSGKRWKIHPDWLFCKHSNRTFKTPEIELLYFLERMSEPGWRWPGSRSAMPPEHAAAMFSNNSSTGRYPSINEKESYYCDRQLMQALVFDARVTGWFSNNTSFNSKDDKGTSASSPIAVLMGLLPRNEFKQRFGVTVAFLATHSGLTRWHEFHSNAAEESGVGETFSQNNTRAIDEIWYKRAVDQHFVREESFVYSVPFDAGESNSEILVTASHAVFHNEGGKTAPAAVVGFQFQHSALYKLFHNITGNACAVDDKDCYILDNNGYVIISTRVHETGRFFGEVNGAIMKRLLEENVYRQVTVYDYQAVCFESKNDNNASSMLLSPLFHLLRVGKWLLHTALWYIVQLLQWAPGVSSHYADMYGDSNDTEPPPPEPHPDHHARNGNGHGKKDDDHWLRYLTLHRTRLKPCDMKRDLYTLFNEKDNVVYNMTAHACERPFVVLPIPFSNLILLVIDQLCPRDGSVVLTVNPQPIDYHLSVNDSLACYKQAREFNRMRPHSCISRHANESGIKLCGKACSVYANLGLLLLCHILSRWL
Protein: Uncharacterized protein Rv0968 (P9WKL9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable copper-exporting P-type ATPase V
- Uncharacterized protein Rv0970
- Copper-sensing transcriptional repressor CsoR
Sequence:
MVWHGFLAKAVPTVVTGAVGVAAYEALRKMVVKAPLRAATVSVAAWGIRLAREAERKAGESAEQARLMFADVLAEASERAGEEVPPLAVAGSDDGHDH