wanglab/gogpt-training-data huggingface dataset:
Protein: Outer membrane protein TolC (Multidrug efflux pump subunit TolC) (Outer membrane factor TolC) (P02930)
Organism: Escherichia coli (strain K12)
Function: Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:15228545, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:21778229, ECO:0000269|PubMed:6337123, ECO:0000269|PubMed:9044294}; Multi-pass membrane protein {ECO:0000269|PubMed:15228545, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:21778229, ECO:0000269|PubMed:6337123, ECO:0000269|PubMed:9044294}.
Interaction partners:
- Multidrug efflux pump subunit AcrA
- Macrolide export protein MacA
- Macrolide export ATP-binding/permease protein MacB
- Multidrug efflux pump subunit AcrB
- Multidrug export protein EmrA
- Probable aminoglycoside efflux pump
- Multidrug resistance protein MdtF
- Multidrug resistance protein MdtA
- Multidrug export protein EmrB
- Multidrug export protein AcrF
Sequence:
MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPENVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN
Protein: Small proline-rich protein 2G (SPR-2G) (Q9BYE4)
Organism: Homo sapiens (Human)
Function: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Late cornified envelope protein 3D
- Small proline-rich protein 2E
- Cornifin-B
- Small proline-rich protein 2F
- Late cornified envelope protein 3E
- Small proline-rich protein 2D
- Late cornified envelope protein 2B
- Late cornified envelope protein 2C
- Corneodesmosin
- Late cornified envelope protein 2D
Sequence:
MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPYLPPPCPPEHCPPPPCQDKCPPVQPYPPCQQKYPPKSK
Protein: Exocyst complex component SEC15A (AtSec15a) (Probable exocyst complex component 6) (Q9LXX6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:19895414}. Note=Localized to globular structures in the perinuclear region.
Interaction partners:
- Exocyst complex component SEC8
- Exocyst complex component SEC6
- Exocyst complex component SEC3A
- Exocyst complex component EXO84A
- Exocyst complex component EXO84C
- Exocyst complex component SEC5B
- Exocyst complex component SEC5A
- Exocyst complex component SEC10a
- Exocyst complex component EXO84B
- Exocyst complex component SEC3B
Sequence:
MMEAKPKRRIVTENGDTGEDLVLATLIGNGDDVGPLVRHAFEMGRPEPLVHQLKNVARKKEAEIEDLCKTHYEEFIVAVDELRGVLVDAEELKSDLASDNFRLQEVGSALLVKLEELLESYAVKKNVTEAIKMSKICVQALELCVKCNSYISEGQFYHALKTMDLIEKSYLKLIPLKVLKLVIERRIPVIKTHIEKKVCSQFNEWLVHIRSSSKNIGQTAIGLTASARQREEEMLERQRRAEEQNTGGLGELAYTLDVEDSEQDSVLKFDLTPLYRAYHIHTILGVPERFRDYYYENRLLQLQSDLQITYTQPFVESYQTFLAQVAGYFIVEDRVIRTAGDFLLADQVETMWETAISKIVAILENQFARMDSPTHLLLVKDYVTLLGTTLRQYGYEVGPVLDALDKSRDKYHELLLEECRKQIVTAITEDTYQQMVIKKEADYENNVLSFNLQTSDIMPAFTYIAPFSSMVPDVCRIIRSYIKGSVDYLSYGVNTNFFSVLRKYLDKILIDVLNEVILETISNNSIGVSQAMQIAANISFLEKASDYFLRHAAQLCGIPSRSVERPQASLAAKVVLKTSRDAAYLALLNVVNTKLDEFMKLTENVNWTTEEMPQGPHEYINEVVIYLETVMSTAQQILPMDALYKVGVGAIEHISNSIVSTFLSDSIKRFNANAVSAINHDLRVIENFADERYHSSGLNEIYKEGSFRSYLVEARQLINLLSSSQPENFMNPVIRERNYNTLDYKKVATICEKFKDSADGIFGSLANRNTKLTAKKKSMDMLKKRLKEFN
Protein: Vitelline membrane protein Vm26Ab (Protein SV23) (Protein TU-4) (P13238)
Organism: Drosophila melanogaster (Fruit fly)
Function: Major early eggshell protein.
Subcellular location: Secreted {ECO:0000269|PubMed:18514182}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:18514182}. Note=Secreted into the perivitelline space by follicle cells and becomes incorporated into the vitelline membrane. {ECO:0000305|PubMed:18514182}.
Interaction partners:
- Vitelline membrane protein Vm26Aa
- Vitelline membrane protein Vm34Ca
- Defective chorion protein, FC177 isoform
- IP19021p
- Protein palisade
- Chorion protein S15
- Vitelline membrane protein Vm32E
- Chorion protein S19
- Chorion protein S36
- Chorion protein c at 7F
Sequence:
MAFNFGHLLIAGLVALSAVSSETIQLQPTQGILIPAPLAENIRVSRAAYGGYGAAPAAPSYSAPAAPAAQAYSAPAAPAYSAPAAPAYSAPAAPAYSAPAAPAYSAPAAPAYSAPASIPSPPCPKNYLFSCQPSLQPVPCSAPAQSYGSAGAYSQYVPQYAVPFVREL
Protein: Ras suppressor protein 1 (RSP-1) (Rsu-1) (Q01730)
Organism: Mus musculus (Mouse)
Function: Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.
Interaction partners:
- LIM and senescent cell antigen-like-containing domain protein 1
- Scaffold protein ILK
- Alpha-parvin
- Beta-parvin
- Gamma-parvin
- LIM and senescent cell antigen-like-containing domain protein 2
Sequence:
MSKSLKKLVEESREKNQPEVDMSDRGISSMLDVNGLFSLAHITQLVLSHNKLTTVPPNVAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSSRLLEVLELTYNNLNEHSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAENNPWVTPIADQFQLGVSHVFEYIRSETYKYLYGRHMQANPEPPKKNNDKSKKISRKPLAAKNK
Protein: Allatostatin (Mas-AS) (P42559)
Organism: Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
Function: Strongly inhibits juvenile hormone biosynthesis in vitro by the corpora allata from fifth-stadium larvae and adult females.
Subcellular location: Secreted.
Interaction partners:
Sequence:
QVRFRQCYFNPISCF
Protein: Nickel import ATP-binding protein NikE (EC 7.2.2.11) (P33594)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01712}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01712}.
Interaction partners:
- Nickel transport system permease protein NikC
- Nickel transport system permease protein NikB
- Nickel-binding periplasmic protein
- Nickel import ATP-binding protein NikD
- Probable D,D-dipeptide transport system permease protein DdpC
- Oligopeptide transport system permease protein OppC
- Glutathione transport system permease protein GsiD
- Dipeptide transport system permease protein DppC
- Nickel-responsive regulator
- Putrescine export system permease protein SapC
Sequence:
MTLLNISGLSHHYAHGGFNGKHQHQAVLNNVSLTLKSGETVALLGRSGCGKSTLARLLVGLESPAQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAVNPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQVVGEKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV
Protein: NADH dehydrogenase subunit 5 (O21799)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
PLSNFWANSPFVLPKNEILAESEFAAPTITKLIPILFSTSGASLAYNVNLVADQFQRAFQTSTFCNRLYSFFNKRWFFDQVLNDFLVRSFLRFGYSVSFEALDKGAIEILGPYGISYTFRRLAERISQLQSG
Protein: Dynein light chain Tctex-type (TCTEX-1 protein homolog) (Q9UTS6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as a non-catalytic accessory component of a dynein complex.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}.
Interaction partners:
- Dynein intermediate chain 1
- Dynein heavy chain, cytoplasmic
- Dynein light chain 1
- Kinetochore protein nsk1
- Karyogamy meiotic segregation protein 1
- UPF0768 protein C1952.04c
- Urease
- Tubulin beta chain
- Inner kinetochore subunit mis6
- Tubulin alpha-1 chain
Sequence:
MSCPIDSKKLEEICLEAAQPVLKASEYDGDKTAEMNQSVIYAVLNALNKETQSYKWIVSSTLVQKLPEDHPSRGVHAAHAACWNCEKDGMTTIKESGEAIDVVLSIMWISI
Protein: Vacuolar protein sorting 15, isoform C (EC 2.7.11.1) (A0A0B4KGX5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGNQLVGIAPSQIYAVEHYFSGQFGSEIAFSSNMGSTRFFKVAKAKTDEGQIVVKVFVKHDPTLPLEDHKERLEGIKKTLSLANAVNCLPFQRVELIDKAAYIMREYVKHSLYDRVSTRPFLTVLEKKWITFQILCALNQCHKQKICHGDIKLENILITSWNWILLSDFASFKPTYLPEDNPADYTYFFDTSRRRTCYIAPERFVKTLASDDDGGNGNMSVIHTDSIIRLAPSYAGNTLLPAMDIFSAGCALLELWTEGTAPFELSQLLAYRRGERDLVEKHLAGIENERLRNLLASMIDIHSMNRKSAEDYLDQERGQLFPEYFYSFLQSYLQMFSSTPIMSPDDKIQCLHKDIGHCIKVLTQAQDLTPEEEEKEEKKDPTLCARLPPEHDGLILIITVVTSCIRGLKQSNTKIAALELLQKLSKYTTSETILDRILPYILHLAQKSPAKVQVQAIETLTACLGMVKDIPRSDANVFPEYILPSITDLASETSAVIVRVAFARNIAALAKSAVYFLEETQRNAPNDMPTPRYEAELNALHDIVRQAVLSLLTDSQPVVKQTLMESGICDLCAFFGKEKANDVILSHIMTFLNDEDKNLRGAFYDNIAGVAGYVGWQASDILVPLLQQGFTDREEFVIAKAIRAVTILIELGHIKKPAVTEIVQETACYLCHPNLWVRHEICGMIATTARNLSAIDVQCKIMPAIGAFLKAPLIQVEKPHILLDCVHPPVPRQIFDSVLRFQDIHHFIRALEARSRVRSQTRQGALPQYEEMGQTLRNLFRRLSSEGLTDLIEMQLLAMNPFLISMKHKALQDLDDTASGNGRIVVSRKQVACHEYPLADKASKMPLDNLIFSSGLWEFIR
Protein: Nuclear fallout, isoform D (RE37018p) (Q7KUK1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Midbody {ECO:0000256|ARBA:ARBA00004214}. Recycling endosome membrane {ECO:0000256|ARBA:ARBA00004654}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004654}.
Interaction partners:
Sequence:
MYVKYPMAEVQLVNDLLLDLRHMKKDCLELLQRKVDDLSDTQNIAEDRTTRTKTEYAVLQARYHMLEEQYRESELRAEERLAEEQKRHREILARVEREASLQNENCQMKIRATEIEATALREEAARLRVLCDKQANDLHRTEEQLELARDQIGVLQQEHEEQAQALRRHEQEKKSTEELMLELGRELQRAREESGARAMPTTSPESIRLEELHQELEEMRQKNRTLEEQNEELQATMLTNQATMLTNGVEQGRHLLNGTLNSLAQELEEMSQAQLQQAFQEKEDENVRLKHYIDTILLNIVENYPQLLEVKPMERK
Protein: alpha-amylase (EC 3.2.1.1) (Q8MM99)
Organism: Drosophila kikkawai (Fruit fly)
Interaction partners:
Sequence:
MFLTKSIVCLAILALASAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGFAGVQVSPVNENAVKDSRPWWERYQPISYKLVTRSGNEEQFASMTRRCNAVGVRIYVDVIFNHMAANGGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAISNYNDANQVRNCELVGLRDLNQGNSYVQEKIAEFLNHLIDLGVAGFRVDAAKHMWPADLGVIYGRLKNLNTDHGFSSGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKAFRGKNQLRYLSNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFSDTDQGPPTTDGHNIASPSFNSDNSCSGGWVCEHRWRQIYNMVAFRNAVGSDAIQNWWDNGSNQIAFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGTKNGSSCTGKTVTVGSDGRASIYLGNSEDDGVLAIHVNAKL
Protein: Pre-mRNA-splicing factor cwf26 (Complexed with cdc5 protein 26) (O94417)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in mRNA splicing.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Pre-mRNA-splicing factor cdc5
- Uncharacterized protein C1782.03
- WW domain-containing protein C2F3.14c
- Pre-mRNA-splicing factor dre4
- Pre-mRNA-splicing factor cwf24
- U2 snRNP component ist3
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cwf2
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor brr2
Sequence:
MHSAHMSNADYIAKKYLRKDQGKKKKKKEKDFVEIQDEDVAGWDDDNSFSLVNRELTSLHDAPTIVANESLKDRDIDAIYQNIEKTTNKPAQLWKAVGNDEVVESEQQDSHDAESIPQFGLLTGKQVTFKAEERRKREEKSSNLDEEELRKSRETVYRDATGRRIDLVLARKEAKRKLKEKEEEARRQKEQQQGVVQVRQQKEYLKELERQKTVPLARYEDDPEYNKELKERSRWNDPAASFLTNKPVSSKATYQGYAPPNRFNIRPGHRWDGIIRGNGFENKWFQRQNERKAQEHEAHMWAIEDM
Protein: Growth hormone (C8CP44)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLLLAFTLLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYFPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
Protein: Cadherin-17 (Intestinal peptide-associated transporter HPT-1) (Liver-intestine cadherin) (LI-cadherin) (Q12864)
Organism: Homo sapiens (Human)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Catenin delta-1
- Catenin beta-1
- Platelet endothelial cell adhesion molecule
- Nectin-1
- Catenin delta-2
- Vascular endothelial growth factor receptor 2
- Vinculin
- Catenin alpha-1
- Tight junction protein 1
- Occludin
Sequence:
MILQAHLHSLCLLMLYLATGYGQEGKFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIEREGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWNDPGAQYSLVDKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSLGSGSLQNDWEVSKINGTHARLSTRHTEFEEREYVVLIRINDGGRPPLEGIVSLPVTFCSCVEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGIILAVVFIRIKKDKGKDNVESAQASEVKPLRS
Protein: V-type proton ATPase subunit B, brain isoform (Vacuolar proton pump subunit B 2) (Q59HF3)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000256|ARBA:ARBA00004132}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000256|ARBA:ARBA00037827}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00037827}. Melanosome {ECO:0000256|ARBA:ARBA00004223}.
Interaction partners:
Sequence:
KMALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSCSCFSLS
Protein: Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha) (Q54R45)
Organism: Dictyostelium discoideum (Social amoeba)
Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Translocon-associated protein subunit gamma
- Translocon-associated protein subunit beta
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Protein transport protein Sec61 subunit beta
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit swp1
- J domain-containing protein
- Protein transport protein Sec61 subunit alpha
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3
Sequence:
MNKLITLLLAVLMIISCVYSDDVEITDDEVVQATPTSDVSFSYIFPDNQDKNFAAGSVVEVLVGFTNNADKALNITHIFASLNHPQDFSVFIQNYTRGDFGIAVEKGHHATLAYRFVPSEYLEPREFGLLISLEYQDGAQNFTQTFFNSTINITEKETSFDMDSFFLILLGLGFVGGIGYIVYGKMPKQKKVRTVSKVNKNAVRVETEDETAEWLSGTSAASSKVKSVQKVVKKNK
Protein: Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (F7EW79)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
LETDGFSPSTWCCSPPGRVYYFNHITNASQWERPSGGSTVGGGSKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRSKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
Protein: Growth hormone (H6UQ64)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MAPGSWFSPLLIAVVTLGLPHETVATFPTMPLSNMFANAVLRAQHLHLLAAETYKEFERTYIPEDQWYTNKNSQAAFCYSETIPAPTGKDDAQQKSDMELLRFSLVLIQSWLTPVQYLSKVFTNNLVFGTKKRVFEKLKDLEEGLQPLMRELEDRSPRGPQLLRPTYDKFDIHLRHGDALLNNYGLLSCFKKDLHKVETYLKVMKCRRFGESNCTI
Protein: RNA-binding protein with multiple splicing 2 (RNA binding protein, mRNA processing factor 2) (Q6ZRY4)
Organism: Homo sapiens (Human)
Function: RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system. Binds NOG mRNA, the major inhibitor of the bone morphogenetic protein (BMP) pathway. Mediates an increase of NOG mRNA levels, thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24860013, ECO:0000269|PubMed:25064856}. Nucleus {ECO:0000269|PubMed:24860013}. Cytoplasm, Stress granule {ECO:0000269|PubMed:24860013}. Note=Localized to cytoplasmic stress granules after oxidative stress. {ECO:0000269|PubMed:24860013}.
Interaction partners:
- RNA-binding protein with multiple splicing
- RNA binding protein fox-1 homolog 2
- Epithelial splicing regulatory protein 1
Sequence:
MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMATPNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTATAAAAALHAQVRWYPSSDTTQQGWKYRQFC
Protein: Mnt, isoform K (X2JDM5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSGIGGIGVLLEAAQFLEQHEKLPQAGGGGGSALGVGVALPQQQQQTVHCKSNSIINNNNSSQHNRNSSSSSNGIIATPPFTNGNGNGTVGVGNASAIFNVSVNANGNGLSNGHSSPRSQLAAAATAHDYEYSAAGVANGHSEGRPHVSDFMLLAAAATSATSATPATATSAAATAASNPAKRKLSSIAEIPSKFLVVSDAKGVYSAHTHPNGFAADSLGVDNNETMIKKLMQNLQSQRQQQSLQQLRSLRPAEISLTPPPAATRKVDISNSRTRSYSLSNVSAARDQQDHPQHQQHANHMQIQQHYGYMRSNIGGVIYGLHKDSADSAASSACGAGAGAAAVGMSIASSAPAAGSQLSAHHHTGHGGRRRTTSSNSNGAGTREVHNKLEKERRAQLKECYDLLKKVLPMGDEDRKKTSNLTILDTAHKYVNSLSHEVCEQEAKIEKLAKQKIELQKRLKQLSLRRESPPTDQQIIPQADKAVCLATTATTAPPTAASGHNGTTILFDAGNACATGQLTTVINKTNGGATAAASSKHNGNHTGGATTTLTPAMGIMTIKNGNGSNGNMLAISPTGGHNHQLHQHHNGSPAGSPSGIGATTGATITRGSPTPSTPSPSPSSSSSGVSLSTSFMGGSSSSSSSSSSSSSSSSSSSSSSPTQQQQIITPTATARSVGLKFHGGAGAAVPAGGGSVNGFHQADKDRNYTFLRLSAGTTAQ
Protein: Bifunctional IPC transferase and DIPP synthase [Includes: 1L-myo-inositol-1-phosphate cytidylyltransferase (IPCT) (EC 2.7.7.74); CDP-L-myo-inositol myo-inositolphosphotransferase (DIPP synthase) (EC 2.7.8.34) (Di-myo-inositol-1,3'-phosphate-1'-phosphate synthase)] (Q1AWQ0)
Organism: Rubrobacter xylanophilus (strain DSM 9941 / JCM 11954 / NBRC 16129 / PRD-1)
Function: Involved in biosynthesis of di-myo-inositol phosphate (DIP), a widespread organic solute in microorganisms adapted to hot environments. Catalyzes the condensation of CTP and L-myo-inositol-1-phosphate into CDP-L-myo-inositol, as well as the biosynthesis of di-myo-inositol-1,3'-phosphate-1'-phosphate (DIPP) from CDP-L-myo-inositol and L-myo-inositol-1-phosphate.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Inositol-3-phosphate synthase
- Inositol-3-phosphate synthase
- Inositol-1-monophosphatase
- Inositol-1-monophosphatase
- CinA-like protein
Sequence:
MPDERTTGREGVGAAVLAAGFGERLRECGRPKPLARVAGLTLLERTVRTLRAGGLEGEIVVVVGHRGEEVAGHCKARGLPVRVVENPDYPRGNGTSVLAAMRFLPERFVVAMVDHIHTPESVRRLLRCEGDFVAAVDTRPVYADPGEATRVRLEGGRVVEFGKNLPRYDGLDAGLFLCSRPALERLREASGGERLSWNDLKRAWLASGGEVVACDLAGAPWTDVDTPQDLRLSEEMVLGWAASGNDGPVSRHINRRISRRITRRLLDTPLSPDQVSLLSFALAALGAGLLAAGRLRLGGALVQLASIVDGCDGELARARLESSPRGAVFDATLDRWADALIISGLALGAGTRLAAAAGYPALAGALLVSYTRARWEAALGRMPSRFTGLGATRDVRLAVLALGGLLGAPGAALLATGALGNAEALRRLLALKRGRS
Protein: Hexosyltransferase (EC 2.4.1.-) (D3ZRM3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000256|ARBA:ARBA00004447, ECO:0000256|RuleBase:RU364016}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004447, ECO:0000256|RuleBase:RU364016}.
Interaction partners:
- Hexosyltransferase
- Hexosyltransferase
- Hexosyltransferase
- Hexosyltransferase
- Hexosyltransferase
Sequence:
MAARGRRAWLSMLLGLVLGFVLASRLVLPRASELKRVGPRRRPNPEGCRPGQAASQPGGAPGDARGAQLWPQGSAAEGVPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVEFFSSEGSDTSIPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLESFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVILSREVLRRMAPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHSSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTIQLHREIVLMSKYSSTEIQKEDLQLGIPPSFMRFQARQREEILEWEFLTGKYLYSATEGQPPRRGMDSAQREALDDIVLQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEGLDAQELADRINQDSGSLSFLSNSLKKLVPFQLPGSKMEHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNLNVKLVILLFNSDSNPDKAKQVELMRDYRVKYPKADMQVLPVSGGFSRALALEVGSSQFSNESLLFFCDVDLVFTAEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTFGSTQQLAEMWLEKNDPSYSRGGNGSARTV
Protein: NADH-cytochrome b5 reductase (EC 1.6.2.2) (Q0E8F4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTEFDFVPLAVGVVAVLAGALIVHYLLNKKSTKPRREPNRTARLRTLVDPNDKYLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISSDEDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQKHPDQFKIWYTVDKANEAWSYNTGHVNDDMMQQHLYPPGEDTLCLLCGPPPMVNYTCIPGLERLGHRAEQRFSY
Protein: Hepatocyte nuclear factor 3-gamma (HNF-3-gamma) (HNF-3G) (Fork head-related protein FKH H3) (Forkhead box protein A3) (Transcription factor 3G) (TCF-3G) (P55318)
Organism: Homo sapiens (Human)
Function: Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC1 promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089, ECO:0000269|PubMed:19706729}.
Interaction partners:
- Hepatocyte nuclear factor 1-alpha
- Hepatocyte nuclear factor 3-alpha
- Transcription factor GATA-4
- Transthyretin
Sequence:
MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMTLNPLSSPYPPGGLPASPLPSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSLLNAS