wanglab/gogpt-training-data huggingface dataset:
Protein: Alpha/beta hydrolase domain-containing protein WAV2 (EC 3.-.-.-) (Protein WAVY GROWTH 2) (Q8RXP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the regulation of root growth. Involved in the suppression of the root bending in response to touch stimuli, gravity and light. Regulates negatively stimulus-induced root bending through inhibition of root tip rotation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15659627}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- E3 ubiquitin-protein ligase WAV3
- Protein translocase subunit SECA1, chloroplastic
- Prolyl endopeptidase
- Acylamino-acid-releasing enzyme
- Wall-associated receptor kinase 3
Sequence:
MVTYVSALFYGFGGIVVAGVALLVAFQEKLVYVPVLPGLSKSYPITPARLNLIYEDIWLQSSDGVRLHAWFIKMFPECRGPTILFFQENAGNIAHRLEMVRIMIQKLKCNVFMLSYRGYGASEGYPSQQGIIKDAQAALDHLSGRTDIDTSRIVVFGRSLGGAVGAVLTKNNPDKVSALILENTFTSILDMAGVLLPFLKWFIGGSGTKSLKLLNFVVRSPWKTIDAIAEIKQPVLFLSGLQDEMVPPFHMKMLYAKAAARNPQCTFVEFPSGMHMDTWLSGGEVYWKTNLQFLEKYAPEKRKEDTGR
Protein: Aminoacylase, putative (EC 3.5.1.14) (Q4GYS3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Peptidase T, putative
- 2,4-dienoyl-coa reductase-like protein
Sequence:
MTFISSLIQAVQPEVVQWRRHIHENPCLSHKEQQTADYVESILRSMPAKLDIRRLTPSSVVADLRGGAGDGPTYALRADMDALPLQEESGEPFSSKLPGVMHACGHDAHTAILLGAIKVLCHVKDKICGTIRFIFQHAEEVIPSGAKQLVQLGVLDGVKMIFGLAVDVSNPPGTVLCKSGVLTSACNDFDIVIQGASGHASQPELCIDPIVIGAQVVMSLQTIVSRRIGALTTPVLSIATFQGGRGGYNVIPDTVHLRGTLRCLDSGVQKRVPAMVEEIVAGITSAHGAKHTVSWLEPNIVTYNNEAAYDVVKRVAEHVVSGITFVELPTAMTGVTDFGEYGAVIPGCLFLLGAGNETNNSVSNHNYSSRFRLNENVMVDGVRMFVGLMMTLAVPDAPSPGT
Protein: Unconventional myosin-VI (Unconventional myosin-6) (F1R4R9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, microvillus {ECO:0000256|ARBA:ARBA00004105}. Cell projection, ruffle membrane {ECO:0000256|ARBA:ARBA00004632}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane, clathrin-coated pit {ECO:0000256|ARBA:ARBA00004600}.
Interaction partners:
Sequence:
MDDGKPVWAPHPTDGFQLGMIVDIGADALTIEPLHQRGKTFLAPISQVFPAEDDVNKHVEDNCSLMYLNEATLLNNIRIRYSKDMIYTFVANILIAVNPYFDIPKLYSPESIKSYQGRSLGTLPPHVYAIADKAYRDMRVLKMSQSIIVSGESGAGKTENTKFVLRYLTTSYGTGQDIDERIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKNAVVGGFVSHYLLEKSRICMQSQEERNYHIFYRLCAGASEDIRNMLHLNSPDSFRYLNRGCTRYFANKDSDKQIMQNRKSPEDHKHGKVGALKDPLLDDLGDFNRMVVAMKKIGLDDTEKLNLFRVVAGVLHLGNIDFEETGSTSGGCILKNQSSQTLEYCADLLGLDQDDLRVSLTTRVMLTTAGGAKGTVIKVPLKVEQANNARDALAKAVYSRLFDHVVKRVNQCFPFDTSSNFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQREGLGVNEVHYVDNQDCIDLVEAKLVGVLDILDEENRLPQPSDQHFAEAVHSKHKDHFRLTVPRKSKLTIHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLVCESKDKFVRDLFENNSNSKDSKQKAGKLSFISVGNKFKTQLNLLLEKLRSTGSSFIRCVKPNLKMVSHQFEGAQILSQLQCSGMVSVLDLMQGGFPSRAPFHELYNMYKQYMPNKLTRLDPRLFCKALFKALGLNENDYKFGLTRVFFRPGKFAEFDQIMKSDPDHLAELVKRVNKWLVCSRWKKVQWCTLSVIKLRNKMSYRASACIRIQKTVRMWLCRRRHKPRVDGLVKVKNLRKRMERFNEAVNGLKEGKAEMSKQIEELAASTDALMAKIKTTVMSRKEIEQEYEGLVKRSEQLLSSMQKKKQEQEETERLKHIQEEMEKERKRHEEEEQLRKQEEEDRRMKSEMEQKRKQEEEERKKREEEERVLQAELEMQLALDREEETQRQTILEQERRDRELAMRIAQNEAELIQDEAQMDPILRRGAQVQANKVAAGVKKYDLSKWKYAELRDAINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTDTEMRAPKSVTDYAQQNPAPPVPARQQEIAMNRQQRYFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELHPDKQPILLVAGKDDMEMCELSLEETGLTRKRGAEILPRQFEEIWERCGGIQYLKNAIESKQARPTYATAMLQNLLK
Protein: ATP-binding cassette sub-family G member 1 (Zgc:162197 protein) (A4QNW0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MACLMAAFSFNNTTVTNSIIMNTNGPPDLMLDPRTVCVSIDEMMSNHVSSQQTPLLHAHLKKVENNLTEAQRFSYLPRRPAVNIEFKDLSYSVPEGPWWRKKGYKTLLKGISGNFTGGALVAIMGPSGAGKSTLMNILAGYRETGMKGEILINGHPRDLRSFRKVSCYIMQDDMLLPHLTVQEAMMVSANLKLQEKDEGRREMVREILTALGLLECAKTRTSHLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSSSCFQVVSLMKALAQGGRTVICTIHQPSAKVFELFDKLYVLSQGQCIYRGKVSSLIPYLRDLGLSCPTYHNPADFIMEVASGEYGDQTARLVKAVQEHKCEKDYKTEMNGNGVHNPFLWHRPSDEESSSSEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRIMSHLGIGILIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIVFPVAYCSIVYWMTSQPSDAVRFILFLALGTLTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPKYLQWISYISYVRYGFEGVILSIYGLDREDLHCDKDETCHFQKSEAILKELDVEDAKLYMDFIVLGIFFISLRLIAYFVLRYKISAER
Protein: LD43161p (Q7K4E2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQKEIETIDYIDKEKENDRNRRAVSYGGDATSSPHSATIPRAAPRRVALMKDPPPPPPPKPQLGSKADSVSHLASKYPQSEYNLIQKIDSNSTLTAPAQYQPQNFYANTGTISSTNGYGSLLCHASSTTSPLAVRKRDKLLHRFSDAATLGRKLKKKKNTNRTCRSMTEAIEMLADPVIEDEFFGDRTTWEYHTVAVTRVPGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKGGPAEDRLQVNDRIISVNGVSLENVEYATAVQVLRDSGNTVQLVVKRRVPLNPINAAGAVQHQHSHSLSSVGLMANGSGGVAPTPITSLSQPNSLNSSLVQNASSGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKAREQLNANGYSLQEGDIITRIHNTNCGDTMSLKEAKKIIDGCKERLNLVVLRDITNQTAVSQLNLNNSASHQASGNIYATHQPQVSGCSSSNNNLEDPYLPGGASYSSQNLYVQPPTRTSNGPNINGNGLNDEKSNLTPRGRSRGPIMDGVSLQQLDRPVTPTRGRSAAIDEPPRPPPPRGSSGGAAQEDFYSSRRQLYEERQSAEPRFISFQKEGSVGIRLTGGNEAGIFVTAVQPGSPASLQGLMPGDKILKVNDMDMNGVTREEAVLFLLSLQDRIDLIVQYCKEEYDEVVTNQRGDSFHIKTHFHCDNPSKGEMAFKAGDVFRVIDTLHNGVVGSWQVLKIGRGHQEMQRGVIPNKSRAEELATAQFNATKKEMNANESRGNFFRRRRSTHRRSKSLSRENWDDVVFSDSISKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKFSTPLQDDDKSAATSGKCRIVRLSNIRDVMDRGKHALLDITPNAVDRLNYAQFYPVVIFLKTDSKHVIKQLRHGLPKAAHKSSKKLLEQCQKLERVWSHIFSTQIALSDEESWYRKLRDSIDLQQSGAVWMSESKTKTKYISSWSFPA
Protein: RRM domain-containing protein (Q583W2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQSTKGTTLPKQRPASTAPLEATKTLMPLHELPSFRRDLLSRSVFVLGLRTTAEMRELLSLMKRHCGIITGAFRVADFASGGMSTGGSMAVQGTAVDSRSALSNAGGCVVVCLTFRTEEGAHLAQRMDNTALVYGSRFVVLPATRFHQNISQVSSKKQRNMPQHERLWQLLFSPTVGGSNIDWAAAAGAVNRGELLMLHPSDLPVDVTSDGTSSGGGASGAAYMKRQVDGGTHSTGDDDKFRLSHYPAAAAPADDLNGARNFSTTPATTTAVTAPVPLYTPRAAVDTENLGRSNTLQQQYYNDVYESSRTPFLSTVSDIASSILTSTGSGNTEYIPRVGRAAQQTDLYGSPPLRQRVEPSRGQPLAERVTAHSQRLTVEGNETESRTNNVTTNSVYIPRVHSLGSLVMDALPFASSLISTLLRAVSSPSQQHLTADATAGYERINEGEAEESRIREMLGMGDWRDARGRKRMRHGEDARGTPVRYISSRGNEVAGTTEEKFYNFEGGFTTLSPDVLNTRFSPSGMAAVPMTVAGGEAGGGVTGPMGSFYAAGRRHGGGQDLRRSLLHAMMSAASLRAQGNGSGVGNDNSDLTASAARSDLPLPPVPDNASNEEVREYIMRNVRLLPAEGQRQQQMRYVRGTDVAAAAAAATTTPAGGGSSFIPFVSAVSSLFRRVNSVWRG
Protein: GRF1-interacting factor 2 (F4HQJ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MQQQQSPQMFPMVPSIPPANNITTEQIQKMLGGSGNFESGFQEWTLKLDACLMLLFCTFSWLDYLDENKKLIMAIMENQNLGKLAECAQYQALLQKNLMYLAAIADAQPPPPTPGPSPSTAVAAQMATPHSGMQPPSYFMQHPQASPAGIFAPRGPLQFGSPLQFQDPQQQQQIHQQAMQGHMGIRPMGMTNNGMQHAMQQPETGLGGNVGLRGGKQDGADGQGKDDGK
Protein: Polycomb protein Scm (Sex comb on midleg protein) (Q9VHA0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Polyhomeotic-proximal chromatin protein
- E3 ubiquitin-protein ligase RING1
- Polycomb group protein Psc
- Protein suppressor 2 of zeste
- Polycomb group protein Pc
- Polycomb protein Sfmbt
- Histone-lysine N-methyltransferase E
- Polycomb protein esc
- Polycomb protein Su
- Polycomb protein esc
Sequence:
MSGGRDSSTSSGSNSAAPGASTNATSSASASASSTSTSASPGSTTSPASTQRQRGRPAKRATCTWCGEGKLPLQYVLPTQTGKKEFCSETCIAEFRKAYSKGACTQCDNVIRDGAPNKEFCSIMCMNKHQKKNCSTRHSGGSASGKGLAESERKLLASGAPAPTGPFQYESFHVFDWDAYLEETGSEAAPAKCFKQAQNPPNNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFWRLVDSTEIHAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAPEEIFQPEPPEPEENLFKVGQKLEAVDKKNPQLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQPPGHKSRMDSSSSKQRCPRPRYTVVAESEAMVPASPATAHFHPNCKGGPFINNSKLPCMVTGPTYQTLAKLCLQEVLAASTDTQQLSKLLFALEGDVHIVTAAGKNFTVKIPSPMRMKDDESLAQFIETLCTTCRACANLISLVHETEECKKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEKIIKQELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSASSTALAAGGVTAAKAATAPAGAAATAGASPSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESNDNSLAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLVNKVNGRRNNLAL
Protein: NAC domain-containing protein 17 (ANAC017) (Protein NTM1-like 7) (Protein REGULATORS OF AOX1A 2) (Q9XIC5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Transcriptional activator that acts as positive regulator of AOX1A during mitochondrial dysfunction. Binds directly to AOX1A promoter. Mediates mitochondrial retrograde signaling.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:24045017}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353, ECO:0000269|PubMed:24045017}. Note=Localized primarily in endoplasmic reticulum membrane as dormant form and, upon abiotic stress, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP). {ECO:0000269|PubMed:24045017}.
Interaction partners:
- Ubiquinol oxidase 1a, mitochondrial
- Inactive poly [ADP-ribose] polymerase RCD1
- Cytosolic sulfotransferase 12
- Cyclin-dependent kinase E-1
- Protein YLS7
- At1g30160
- Ubiquinol oxidase 3, mitochondrial
- Probable WRKY transcription factor 40
- Transcription initiation factor TFIID subunit 4
- Transcription initiation factor TFIID subunit 4b
Sequence:
MADSSPDSCFKGGKFSAPGFRFHPTDEELVMYYLKRKICRKRLRVNVIGVVDVYKMDPEELPGQSMLKTGDRQWFYFTPRSRKYPNAARSNRGTENGYWKATGKDRVIEYNSRSVGLKKTLVFYRGRAPSGERTDWVMHEYTMDEDELGRCKNPQEYYALYKLFKKSGAGPKNGEQYGAPFQEEEWVDDDNEDVNAIAVAVPEQPVVRYEDARRVDERRLFNPVILQLEDIDELLNGIPNAPGVPQRCIPQVNSEEELQSTLVNNSAREFLPNGQQYNRPSSFDSLETAEVTSAPLVFEKEDFIEMDDLLLIPEFGASSTEKAAQFSNHGEFDDFNEFDQLFHDVSMSLDMEPIDQGTSANLSSLSDSANYTSDQKQQLLYQQFQDQTPENQLNNIMDPSTTLNQITSDIWFEDDQAILFDQQQSFSGAFASPSSGVMPDSTNPTMSVNAQGHEIQNGGGTTSQFSSALWALMDSIPSTPASACEGPLNRTFVRMSSFSRMRFNGKANGTPVSTTIAKKGIRNRGFLLLSIVGALCAIFWVLVATVRVSGRSLLLKD
Protein: TonB-dependent receptor (Q9I258)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell outer membrane {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}.
Interaction partners:
- ABC-type dipeptide transporter
- Probable permease of ABC transporter
- Probable binding protein component of ABC transporter
- Inner membrane ABC transporter permease protein YejB
Sequence:
MVTGSRIPRAQQEGPSPVTVISSEEIQNRGYRNVFEALQTQTQNTGMTQGEDYGNTWQPAANALNLRDLGPNHTLVLINGRRVADYPTAYGGSVNFTNLANIPAVMIDRIEILSGGASAIYGSDAIAGVVNIVLKKKFDGVDVNLRAGTTERGGGDNQRLQLVGGGATGDFEGLFGLQVEQRQPVWANQRGFMDSYPDGNNVGYRLNPQSGRYLGDASCAGLGGLFGGNVAPVPGARGGYRCMTDQYYNNYWTLQTKKENYDGYAGGTWHLSDSGKLFADLLFGFDHLQNNTRGPSFTSPDFINASSGDLERWYRLFSPEEIGGKSSNNSKWREVSWTGTLGYSDRVANTSWEYELAATRSEYRSDRTTRYTPAAGILDLYLGRKLGERDGYPVYDPDPARLGRPLSEEEWRSLRRNVTQHSESYSQTYSFTGNGELFDLPAGPVAFAGVLEVGKQGYRIRPDSQYNDGSLYNVSKASSSGGSRDRYAAGGEFSIPLHDTLLASAAGRWDQYRFSGRTEEQTTYNLGLEWRPLTSLLLRGSYGTSFRAPDLNYIYQADANGYYPAQKDYYGCEKGVDGACKNGRVDYVQSGTPDLKSERGRYWSYGFVWSPSSRFDFSADYYHIQIDDLLTTLDPDKLLRDEAACRSGGLDPDSAQCRDTLARVERNAGDASVDPNRLNKVYVNAINAAKERTSGIDLRSNIRWGAGDYGAFSSTLGYTLVLSHDYKQSDDYPSENQRDSLDSHDWRSKLNASLTWDYAQFTSTLFAVRYGSVTNAAGSGRLSPWTVFNASARYRLNERASVGLTVNNLLDQIKEDDSDGWPYYPTGNYDAMGRQWWLDFSYHFGG
Protein: KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68) (Q91V33)
Organism: Rattus norvegicus (Rat)
Function: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. May not be involved in the nucleocytoplasmic export of unspliced (CTE)-containing RNA species. RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). Can regulate CD44 alternative splicing in a Ras pathway-dependent manner. In cooperation with HNRNPA1 modulates alternative splicing of BCL2L1 by promoting splicing toward isoform Bcl-X(S), and of SMN1. Can regulate alternative splicing of NRXN1 and NRXN3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. In a neuronal activity-dependent manner cooperates synergistically with KHDRBS2/SLIM-1 in regulation of NRXN1 exon skipping at AS4. The cooperation with KHDRBS2/SLIM-1 is antagonistic for regulation of NXRN3 alternative splicing at AS4 (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q07666}. Cytoplasm {ECO:0000250|UniProtKB:Q07666}. Membrane {ECO:0000250|UniProtKB:Q07666}. Note=Predominantly located in the nucleus but also located partially in the cytoplasm. {ECO:0000250|UniProtKB:Q07666}.
Interaction partners:
- Tyrosine-protein kinase
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase Fyn
- Ras GTPase-activating protein 1
- ATP-dependent RNA helicase A
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoprotein K
- Growth factor receptor-bound protein 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Sequence:
MQRRDDPAARLTRSSGRSCSKDPSGAHPSVRLTPSRPSPLPHRSRGGGGGPRGGARASPATQPPPLLPPSNPGPDATVVGSAPTPLLPPSATAAAKMEPENKYLPELMAEKDSLDPSFTHAMQLLSVEIEKIQKGESKKDDEENYLDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPEPSRGRGVSVRGRGAAPPPPPVPRGRGVGPPRGALVRGTPVRGSITRGATVTRGVPPPPTVRGAPTPRARTAGIQRIPLPPTPAPETYEDYGYDDSYAEQSYEGYEGYYSQSQGESEYYDYGHGELQDSYEAYGQDDWNGTRPSLKAPPARPVKGAYREHPYGRY
Protein: OpaR (Q79YV4)
Organism: Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Interaction partners:
Sequence:
MDSIAKRPRTRLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDEVLNHVVRQFSNFLSDNIDLDIHARENIANITNAMIELVSQDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLVQNMFIKAIERGEVCDQHDSEHLANLFHGICYSLFVQANRFKGEAELKELVSAYLDMLCIYNREH
Protein: Small ubiquitin-related modifier (SUMO) (Ubiquitin-like protein SMT3) (P55853)
Organism: Caenorhabditis elegans
Function: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Probably by sumoylating bet-1, prevents muscle myosin depletion in aging adults probably by preventing myoblast growth factor receptor egl-15 overexpression. Plays a role in the attenuation of the let-60/ras pathway. Plays a role in male tail tip morphogenesis. Plays a role in the mitochondrial stress response with its covalent attachment to transcription factors dve-1 and afts-1 negatively regulating the mitochondrial unfolded protein response.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25475837}. Nucleus {ECO:0000269|PubMed:25475837}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:25475837}. Chromosome {ECO:0000269|PubMed:25475837}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:25475837}. Note=At the first embryonic mitotic division, enriched in the nucleus and released to the cytoplasm when the nuclear envelope breaks down at the start of mitosis. During mitosis, localizes to the metaphase plate and to the centrosomal region. Also localizes to segregating chromosomes at the beginning of anaphase. At late anaphase and telophase, observed in the spindle midzone and in the two daughter nuclei. {ECO:0000269|PubMed:25475837}.
Interaction partners:
- SUMO-activating enzyme subunit uba-2
- SUMO-conjugating enzyme UBC9
- Sentrin-specific protease
- E3 SUMO-protein ligase gei-17
- SUMO-activating enzyme subunit aos-1
- UBC core domain-containing protein
- Ran GTPase-activating protein 2
- Ubiquitin-like protein NEDD8
- Ubiquitin-like protease 2
- Nuclear Pore complex Protein
Sequence:
MADDAAQAGDNAEYIKIKVVGQDSNEVHFRVKYGTSMAKLKKSYADRTGVAVNSLRFLFDGRRINDDDTPKTLEMEDDDVIEVYQEQLGGF
Protein: 40S ribosomal protein S6 (A2A3R5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK
Protein: Pseudin-B (P86915)
Organism: Pseudis bolbodactyla (Frog)
Function: Antimicrobial peptide with activity against both Gram-positive and Gram-negative bacteria. Has been tested against X.axonopodis pv. glycines (MIC<2 uM), E.coli ATCC 25922 (MIC=6 uM), S.aureus ATCC 29313 (MIC=6 uM) and P.aeruginosa ATCC 27853 (MIC=50 uM).
Subcellular location: Secreted {ECO:0000269|Ref.1}.
Interaction partners:
Sequence:
GLNTLKKVIQGLHEVIKLVNNHA
Protein: Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72) (P13667)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000269|PubMed:12643545}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). {ECO:0000269|PubMed:17081065}.
Interaction partners:
- Endoplasmin
- Hypoxia up-regulated protein 1
- Peptidyl-prolyl cis-trans isomerase B
- Endoplasmic reticulum chaperone BiP
- DnaJ homolog subfamily B member 11
- ERO1-like protein beta
- ERO1-like protein alpha
- Calreticulin
- Calnexin
- Stromal cell-derived factor 2-like protein 1
Sequence:
MRPRKAFLLLLLLGLVQLLAVAGAEGPDEDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLVVMQPEKFQSKYEPRSHMMDVQGSTQDSAIKDFVLKYALPLVGHRKVSNDAKRYTRRPLVVVYYSVDFSFDYRAATQFWRSKVLEVAKDFPEYTFAIADEEDYAGEVKDLGLSESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL
Protein: Golgin subfamily A member 1 (Golgin-97) (Q9CW79)
Organism: Mus musculus (Mouse)
Function: Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:11412037}; Peripheral membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:11412037}.
Interaction partners:
- Ras-related protein Rab-6A
- ADP-ribosylation factor-like protein 1
- GRIP and coiled-coil domain-containing protein 2
- Vesicle transport through interaction with t-SNAREs homolog 1A
- Trans-Golgi network integral membrane protein 1
- Golgin subfamily A member 4
- Syntaxin-6
- Golgin B1
- Syntaxin-16
- ADP-ribosylation factor-related protein 1
Sequence:
MFAKLKKKIAEETAVAQRPGGTTRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQASRAKMAEGLALALARKDQEWSEKMEQLEKDKRFLTSQLQEVKNQSLSLFQKRDEIDELEGFQQQEISKVKHMLLKKEECLGKMEQELDARTRELNRTQEELVTSNQLSSDLNERLEELQRHCSTLEEQRDHLTASKAGAEHKIVVLEQKEQELQAIIQQHSIDLQKVTAETQEKEKVITHLQEKVIFLEKRLEQNLSGEDHVQELLKEKTVAEQNLEDTRQQLLAARNSHTKALYLLETRVKDLERSLQAAEEQLSQSRNVVADQEAQIQKLITTNQENSLSQQQVLALEQHCRERIHALEAQIEALEQTRVADQIASEQGMLQLQQENVALKESRNECEHSLQHHQLELKKLKDEWSQREIVSVAMAQALEEVRKQREEFQQQATELTAIIEEKNQSLCEKDEALLQKEQELRQLEKGHSSALLQMHKLQRELEALKTCKAQEAMPATTGEDCLPLQGQEPLVISKAMQNSEYELPAAEGTPNGEVGASDLKQLQKEKQDLEQQLIEKNKIMKQMQQRMLELKKTLQKELKIRPDSELFEVREKTGPEIPNMAPSVTNNTDLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPTPKGSIRPSISNPRIPWS
Protein: Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (Malate dehydrogenase [quinone] cytochrome b560 subunit) (QPs-1) (QPs1) (Succinate dehydrogenase complex subunit C) (P35720)
Organism: Bos taurus (Bovine)
Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q99643}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q99643}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Fumarate hydratase, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- Succinate dehydrogenase assembly factor 2, mitochondrial
- Cytochrome c oxidase subunit 2
Sequence:
MAALLLRHVGRHCLRAHLSPQLCIRNAVPLGTTAKEEMERFWSKNTTLNRPLSPHISIYGWSLPMAMSICHRGTGIALSAGVSLFGLSALLVPGSFESHLEFVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLTISQLHQSGVAVLVLTVLSSVGLAAM
Protein: Transcription factor tau 55 kDa subunit (TFIIIC 55 kDa subunit) (Transcription factor C subunit 7) (Q12415)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Transcription factor tau 131 kDa subunit
- Transcription factor tau 91 kDa subunit
- Transcription factor tau 138 kDa subunit
- Transcription factor tau 95 kDa subunit
- Transcription factor tau 60 kDa subunit
- Transcription factor IIIB 70 kDa subunit
- Transcription factor TFIIIB component B''
- TATA-box-binding protein
- Calpain-like protease 1
Sequence:
MVVNTIYIARHGYRSNWLPEGPYPDPLTGIDSDVPLAEHGVQQAKELAHYLLSLDNQPEAAFASPFYRCLETVQPIAKLLEIPVYLERGIGEWYRPDRKPVIPVPAGYEILSKFFPGVISQEWDSTLTPNEKGETEQEMYMRFKKFWPLFIERVEKEYPNVECILLVTHAASKIALGMSLLGYDNPRMSLNENGDKIRSGSCSLDKYEILKKSYDTIDETDDQTSFTYIPFSDRKWVLTMNGNTEFLSSGEEMNWNFDCVAEAGSDADIKKRQMTKKTSSPIPEADDQTEVETVYISVDIPSGNYKERTEIAKSAILQYSGLETDAPLFRIGNRLYEGSWERLVGTELAFPNAAHVHKKTAGLLSPTEENETTNAGQSKGSSTANDPNIQIQEEDVGLPDSTNTSRDHTGDKEEVQSEKIYRIKERIVLSNVRPM