wanglab/gogpt-training-data huggingface dataset:
Protein: CASK interacting protein 1 (F1MB71)
Organism: Bos taurus (Bovine)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Peripheral plasma membrane protein CASK
Sequence:
MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELITLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCTALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDNGINAHVRNTYSQTALDIVHQFTTSQASKEIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGPRAGAEPSPPQGGSSAGPTVPPEEIWVLRKPFAGGDRSGSLSSAAGGRSVGGHTLHAGSEGVKLLATVLSQKPVSDSSPGDSPVKPPEGPAAATRAQPPAAHAGPGYGEQPPKKLEAASEGKGAEAVSQWLATFQLQLYAPNFISAGYDLPTISRMTPEDLTAIGVTKPGHRKKITAEISGLSLPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPPPEPAPADCQSPKMTTFQDSELSGELQAALTGPAEGAAAATAPAEKPANHLPPTPRASGRQEPSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPKEARPSRHGHSVKRASVPPVPGKPRQVLPPGASHFTPPQTPTKPRPSSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVESEAGPAAPGPAPAAVPTPVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPSGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSAMASANLADEPAPDAETEGAGAEDGRLGVRAQSRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPMPHPASPEPGRVATVLASVKHKEAIGPDGEVVNRRRTLSGPVTGLLATARRGSGEPAGPADHGQLVEEGAARQRPRGPAKGEAGAEGPPLARVEASATLKRRIRAKQSQQENVKFILTESDTVKRRPKVKEREAGPEPPPPPLSVYQNGTGTVRRRPASEQAGPPELPPPPPPAEPPPSDLMHLPPLPPPDSDARKLAKPPVSPKPILAQPVPKIQGSPTPASKKVPLPGPSSPEVKRAHGTPPPVSPKPPPPPTAPKPAKAAAGLQSGSSSPSPAPSPARQQPAALAKPASTPPALSASPASPARPPSPGAPALHVPAKPPRAAAAATGPPAAPDGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGSRPSAAEKSTGSILDDIGSMFDDLADQLDAMLE
Protein: Immunoglobulin-like B protein (Q7X2A1)
Organism: Leptospira interrogans serovar Pomona
Interaction partners:
Sequence:
MKKIFCISIFLSMFFQSCMSWPLLTSLAGLAAGKRGGDSSFFHLLLGNSNPTITRIELSYQDSSIANGTSTALEVTAIFDNGTNQNITDSTYIVPDSQSVVTIQGNRVRGITSGSSIIKAEYNGLYSEQKITVTPAILNSIQVTSLESGILPKGTNRQLSAIGIFSDGSHQDISNDPLIVWSSSNPDLVQVDDSGLASGINLGTAHIRASFQSKQGAEEMTVGDAVLSQIQVTSNNLNIPLGKKQKLTATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASTENIIGSVKLIVTPAALVSISVSPTNSTVAKGLQENFKATGIFTDNSNSDITDQVTWDSSNTDILSISNASDSHGLASTLNQGNVKVTASIGGIQGSTDFKVTQEVLTSIEVSPTRTSIAKGLTQKFTAIGIFTDNSKKDITDQVTWNSSSAIVSVSNLDDNKGLGKAHAVGDTTITATLGKVAGKTWLTVVPAVLTSIQINPVNPSLAKGLTQKFTATGIYSDNSNKDITSAVTWFSSDSSIATISNAQKNQGNAYGAATGTTDIKATFGKVSSPVSTLSVTAAKLVEIQITPAAASKAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTDIAEIKNTSGSKGITNTLTPGSSEISAALGSIKSSKVILKVTPAQLISIAVTPINPSVAKGLIRQFKATGTYTDHSVQDVTALATWSSSNPGKAMVNNVTGSVTTVATGNTNIKATIDSISGSSVLNVTPALLTSIEITPTINSITHGLTKQFKATGIFSDKSTQNLTQLVTWISSDPSKIEIENTSGKKGIATASKLGSSNIKAVYKFVQSSPIPITVTDLKLKSITISPSSSSIAKGLTQQFKAIGTFIDGSEQEITNLVTWYSSKSDVAPINNAANAKGLATALSIGSSNISAIYNSISSNKINFNVSAATLDSIKINPVNNNIAKGLTQQYTALGVYSDSTIQDISDSVTWSSSNSSSISISNSTETKGKATALQIGKSKITATYNSISENIDITVSAATLSSISISPINTNINATVSKQFFAMGTYSDGTKADLTSSVTWSSSNKSQSKVSNASKTKGLVTGIASGNSIITATYGSVSGNTILTVNKTDTIAPTVQSVVSLSPTTIQVVYSESINNKEALDLSNYKIINSSNFIGHCSDNTDFNSNSQTADFSLSSIKGSKNTFTITLSHSQILNKSYTLVVNKQGIHDLSSIPNSLSCPNNSDFIGKEQLKLTSAVCNSLNQVIVSFSKPLYSGKEATKSVECSNPSQCESRYKFAGVSSLGSITSVRILDGKVCGGAPADSSKICLTHSLLQSGGQYTIIAANDLNGDGFDNKSWGAIRDSFDQENLQSSPKDRINFIGCGNSPLNFMDGPIVSDPFGDGSDFGFLVDYNNQIYLGPNVKGNQAARFNYDGTFPESIFFSFTQDINATNRASSRDGGIPVPNYVTIGHTGCTLNSADITTGCGPDNEDGRGVFATGSLDKKSHIFIAGSKPKSFNYLYYSSDTDTNLNFKYISMGKITGLATAGTSSIAVLDDRIHVGFAKKNQNLNAPDFGKITFNTSEHNRCAIVNNCEASDGYRGNRFRIDRMPYFGGGSVDVVNYRSYKSDNSSINWGYYVGIDSLFVFKEKLYAANGGFPNSLHNGSIIHSTSANPSPCEGINRCSSWKDTAPRSNPKWHNSPHNNWFSLELTKYRNLIPADKAFSQFAEFNGRLYVTRTICVTKEDHSGLRQSLQTVKGCTDGSYTNRRPQLWKCDPTLTGDTTTCEAEDWSLVGDNGTGFTNFGDNSNHSMTMMVASGSYLYIGFDNENGIQIWRTNLENPGSSSHNWEPIGIGGLRDVTNRQIYSAISGMNFGVNFVYISVGNKNKPVKIYRQQNQ
Protein: Flagellar transcriptional regulator FlhC (A0A0F6B2Q8)
Organism: Salmonella typhimurium (strain 14028s / SGSC 2262)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01891, ECO:0000256|PIRNR:PIRNR003159}.
Interaction partners:
Sequence:
MSEKSIVQEARDIQLAMELINLGARLQMLESETQLSRGRLIRLYKELRGSPPPKGMLPFSTDWFMTWEQNIHASMFCNAWQFLLKTGLCSGVDAVIKAYRLYLEQCPQPPEGPLLALTRAWTLVRFVESGLLELSSCNCCGGNFITHAHQPVGSFACSLCQPPSRAVKRRKLSRDAADIIPQLLDEQIEQAV
Protein: Datilografo, isoform D (H9XVN7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTLDCEKEHDLQLSRSSSAAAISERTLEECWSTLQRLFMHKSAMQQIQQQIPRVGLGTHGVTGSANLGGSITPSSDTKPHQCQQCMKSFSSNHQLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLRNHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATSCPVCHKLFLGTEALVDHMKHVHKEKSPPPGGSASSQFSELNQIVTGNGNGTGSSNEQIATQCTTESNSHQATVGSSLIDSFLGKRRTANHPCPVCGKHYVNEGSLRKHLACHAENSQLTNSLRMWPCSVCQAVFTHENGLLTHMESMRMDPKHQFAAQYVLSRAAAEQRERESLLAVTLAASSGASTRIGIADAGNVLPTGAHNSDGSNSKCPSPSANSECSSNGRLSSSTTSDQDQDIDHGLSENENSNQNNIGSSTNNNNNCTSNNNASSHKMAELRLPGTGQYTMDAELHVANRMSLMAAAAAAVAASRPQDGVDTSAVPSAAVQAAVVNLAAAMRMNNSSNGATPYQQHHADHTQAHQTHILQHAHPHHHQQQQAPQHQQQQLSHLLVHTHPSNSNSRSQSSPNINVPSLQNESTAASIAMNMNVHMMRGSLDPDPSLGGMHGIEVLHQHQQQHHHHHHHHTSNYPQHAVTPTNQHTHPHPQTHQTAHHHTSPETALRMHQAEAILRSHTEAAFRLATGSGPDTGVKCEADQNQLNSNNAGNAGGNSGGNSQQHRFHASSNHQENQRPSDS
Protein: Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1) (Q9HBZ2)
Organism: Homo sapiens (Human)
Function: Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:24465693}.
Interaction partners:
- Hypoxia-inducible factor 1-alpha
- Endothelial PAS domain-containing protein 1
- Neuronal PAS domain-containing protein 4
- Single-minded homolog 1
- Hypoxia-inducible factor 3-alpha
- Aryl hydrocarbon receptor nuclear translocator
- Aryl hydrocarbon receptor
- Single-minded homolog 2
- Aryl hydrocarbon receptor
- Aryl hydrocarbon receptor repressor
Sequence:
MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQGSPFPSGHSGKAFSSSVVHVPGVNDIQSSSSTGQNMSQISRQLNQSQVAWTGSRPPFPGQQIPSQSSKTQSSPFGIGTSHTYPADPSSYSPLSSPATSSPSGNAYSSLANRTPGFAESGQSSGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE
Protein: Glutamate--cysteine ligase (O69666)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MRTISPFLRCRHETCCISNVGEEVTRTTYSREHQREYRRKVRLCLDVFETMLAQTRFEADRPLTGMEIECNLVDADYQPAMSNRYVLDAIADPAYQTELGAYNIEFNVPPRPLPGRTCLELEDEVRASLNDAETKASCSGAHIVMIGILPTLMPEHLTDGWMSASARYAALNESIFKARGEDIPINIAGPEPLSCHAGSIAPESACTSVQLHLQLAPADFPANWNAAQVLAGPQLALGANSPYFFGHQLWSETRIELFTQSTDARPEELKSRGVRPRVWFGERWITSVLDLFQENIRYFPTLLPEVSDEDPLAELSAGRIPHLSELRLHNGTVYRWNRPVYDVVDGRPHLRLENRVLPAGPTVVDMLANHAFYYGALRGLSEADPPLWTQMNFAAAQANFLAAARYGMDAQLDWPGLGEVTTRELVLGTLLPMAHEGLRRWGVDAEVRDRFLGVIGGRAQTGRNGARWQVATVAALQDGGLTRPAALAEMLRRYCEHMHSNEPVHTWDT
Protein: Endonuclease or glycosyl hydrolase (Q9M1Q3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Notchless protein homolog
- F-box protein At2g40910
- Histidine kinase CKI1
- 110 kDa U5 small nuclear ribonucleoprotein component CLO
- DEAD-box ATP-dependent RNA helicase 36
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH10
- Protein NUCLEOLAR FACTOR 1
- ATP-dependent RNA helicase DEAH13
Sequence:
MNTAGKEDLGTADTAEAQYVMAKTSVWWDIENCQVPKGLDAHGIAQNISSALKKMNYCGRVSISAYGDTSGIPHVIQHALNSTGIELHHVPAGVKDASDKKILVDMLFWAFDNPAPSNIMLISGDRDFSNALHKLSLRRYNILLAHPPKASAPLSQAATTVWLWTSLLAGGNPLIRGKVKTSQLVANASTSSNVMSSPPHNQFPDPPRSGPLHARQPYLNPDPFVNNRDPNAARPGPSNMRPLCPNAIRRHRQEKLERALPLLILLVFMFMILATVNSN
Protein: Nuclear intron maturase 4, mitochondrial (AtnMat4) (EC 3.1.-.-) (Nuclear intron maturase 2 b) (AtnMat2b) (Q9CA78)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in NAD1 pre-mRNA processing and maturation of introns 1, 3 and 4. Necessary for mitochondrial biogenesis during early developmental stages. Essential for respiratory holocomplex I biogenesis in mitochondria.
Subcellular location: [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:19946041, ECO:0000269|PubMed:24506473}.; SUBCELLULAR LOCATION: [Isoform 2]: Plastid, chloroplast {ECO:0000269|PubMed:19946041, ECO:0000269|PubMed:24506473}.
Interaction partners:
- Nuclear intron maturase 2, mitochondrial
- Nuclear intron maturase 1, mitochondrial
- DEAD-box ATP-dependent RNA helicase 53, mitochondrial
- Pentatricopeptide repeat-containing protein At1g74900, mitochondrial
- RCC1 domain-containing protein RUG3, mitochondrial
- Transcription termination factor MTERF15, mitochondrial
- Protein WHAT'S THIS FACTOR 9
- Pentatricopeptide repeat-containing protein At3g48250
- Transmembrane 9 superfamily member 5
- Pentatricopeptide repeat-containing protein At1g51965
Sequence:
MFRKRNLVLDLLRRCYIETLIPRGLWSRTISTFPKSALLATDNAEMASKETGMFSLAGELASLVEESSSHVDDDSKPRSRMELKRSLELRLKKRVKEQCINGKFSDLLKKVIARPETLRDAYDCIRLNSNVSITERNGSVAFDSIAEELSSGVFDVASNTFSIVARDKTKEVLVLPSVALKVVQEAIRIVLEVVFSPHFSKISHSCRSGRGRASALKYINNNISRSDWCFTLSLNKKLDVSVFENLLSVMEEKVEDSSLSILLRSMFEARVLNLEFGGFPKGHGLPQEGVLSRVLMNIYLDRFDHEFYRISMRHEALGLDSKTDEDSPGSKLRSWFRRQAGEQGLKSTTEQDVALRVYCCRFMDEIYFSVSGPKKVASDIRSEAIGFLRNSLHLDITDETDPSPCEATSGLRVLGTLVRKNVRESPTVKAVHKLKEKVRLFALQKEEAWTLGTVRIGKKWLGHGLKKVKESEIKGLADSNSTLSQISCHRKAGMETDHWYKILLRIWMEDVLRTSADRSEEFVLSKHVVEPTVPQELRDAFYKFQNAAAAYVSSETANLEALLPCPQSHDRPVFFGDVVAPTNAIGRRLYRYGLITAKGYARSNSMLILLDTAQIIDWYSGLVRRWVIWYEGCSNFDEIKALIDNQIRMSCIRTLAAKYRIHENEIEKRLDLELSTIPSAEDIEQEIQHEKLDSPAFDRDEHLTYGLSNSGLCLLSLARLVSESRPCNCFVIGCSMAAPAVYTLHAMERQKFPGWKTGFSVCIPSSLNGRRIGLCKQHLKDLYIGQISLQAVDFGAWR
Protein: Putative ribosomal RNA methyltransferase PB17E12.10c (EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase) (Q8TFH4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- tRNA
- Nucleolar protein 58
- Uncharacterized RNA-binding protein C1827.05c
- Ribosome biogenesis protein NOP53
Sequence:
MSMRIWSRSSSAYSAIARSSSWFNNSLFSSCLLRFYSNPPKKTKKNTLISLRKSAETANEKFIEKINKEHQLFKPGQIVVDLGCAPGIWSTIAARHVGLFGRVIACDIIPCRLPENSSMIQGNILSMEIQLEIAKAAIRSRNSFFRNQQDHNSASIPYLQSVFEEERDTKEKAKIEDLSADVIMSDLGPPFPMVQGFEFWISKLPYLAMQTNEHLAVKDELDSLYLAQAALLFAIKALKPDGIFLCKVLESSHLRSFAEDLSMCFKCVKKIQFKTKIKDELYAVYFCSGKQLSCHSKLLNI
Protein: Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) (MLC1F/MLC3F) (Myosin light chain alkali 1/2) (Myosin light chain A1/A2) (P05976)
Organism: Homo sapiens (Human)
Function: Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
Interaction partners:
- Myosin-7
- Myosin regulatory light chain 11
- Myosin-2
- Myosin-1
- Myosin regulatory light chain 12B
- Troponin T, fast skeletal muscle
- Troponin I, slow skeletal muscle
- Myosin-13
- Nebulin
- Troponin I, fast skeletal muscle
Sequence:
MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI
Protein: F-box protein PP2-A13 (Protein PHLOEM PROTEIN 2-LIKE A13) (AtPP2-A13) (SKP1-interacting partner 9) (Q9LEX0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- F-box/kelch-repeat protein At1g23390
- F-box protein At1g30200
- NAD
- F-box/kelch-repeat protein At5g60570
- At1g62510
- At1g32920/F9L11_25
- GDSL esterase/lipase At1g09390
- Probable ADP-ribosylation factor At2g15310
- GDSL esterase/lipase At5g62930
- Probable methyltransferase PMT24
Sequence:
MGANISGGSPEFDRNDDVYSRKLRLVDLPENCVALIMTRLDPPEICRLARLNRMFRRASSADFIWESKLPANYRVIAHKVFDEITLTKLIKKDLYAKLSQPNLFDDGTKELWIDKNTGRLCLSISSKALRITGIDDRRYWSHIPTDESRFQSAAYVQQIWWFEVGGEFEIQFPSGTYSLFFRIQLGKTSKRLGRRICNSEHIHGWDIKPVRFQLATSDNQQAVSLCYLNNNPGSWSHYHVGDFKVTNPDVSTGIKFSMTQIDCTHTKGGLCIDSVLILPKECAKEVIGSQ
Protein: RuvB-like helicase 1 (EC 3.6.4.12) (Dpontin) (Dpon) (Pontin) (Q9VH07)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth.
Subcellular location: Nucleus {ECO:0000269|PubMed:11080158}.
Interaction partners:
- RuvB-like helicase 2
- Actin-related protein 5
- Transcription-associated protein 1
- Brahma associated protein 55kD
- DNA methyltransferase 1-associated protein 1
- YEATS domain-containing protein 4
- Chromatin-remodeling ATPase INO80
- Inhibitor of growth protein
- Helicase domino
- LD10749p
Sequence:
MKIEEVKSTVRTQRIAAHSHVKGLGLDEVGAAVHSAAGLVGQKAAREAAGIVVDLIKSKKMAGRALLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEGEVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYIEANSGAVKRQGRSDTFATEFDLETEEYVPLPKGDVHKKKEVIQDVTLHDLDVANARPQGGQDVLSMMGQLMKPKKTEITDKLRMEINKVVNKYIDQGIAELVPGVLFIDEIHMLDLETFTYLHKSLESPIAPIVIFATNRGRCVIRGTTDIVSPHGIPLDLLDRLLIIRTLLYSTADMEQIIKLRAQTEGLQLEENAFTRLSEIGTSSTLRYAVQLLTPAHQMCKVNGRNQISKDDIEDVHSLFLDAKRSSKHLSEKNNKFML
Protein: Cell wall mannoprotein PST1 (Haze protective factor 2) (Protoplast secreted protein 1) (Q12355)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a partially redundant function to ECM33 in cell wall integrity. May be involved in a repair mechanism activated in response to cell wall damage.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as GPI-anchored plasma membrane protein (GPI-PMP) as well as non-covalently-linked, soluble protein of the cell wall. Secreted by regenerating protoplasts. In budded cells, concentrates at the surface of the buds.
Interaction partners:
- Cell wall mannoprotein PIR3
- Congo red hypersensitive protein 1
- Covalently-linked cell wall protein 14
- Cell wall mannoprotein HSP150
- 1,3-beta-glucanosyltransferase GAS5
Sequence:
MQLHSLIASTALLITSALAATSSSSSIPSSCTISSHATATAQSDLDKYSRCDTLVGNLTIGGGLKTGALANVKEINGSLTIFNATNLTSFAADSLESITDSLNLQSLTILTSASFGSLQSVDSIKLITLPAISSFTSNIKSANNIYISDTSLQSVDGFSALKKVNVFNVNNNKKLTSIKSPVETVSDSLQFSFNGNQTKITFDDLVWANNISLTDVHSVSFANLQKINSSLGFINNSISSLNFTKLNTIGQTFSIVSNDYLKNLSFSNLSTIGGALVVANNTGLQKIGGLDNLTTIGGTLEVVGNFTSLNLDSLKSVKGGADVESKSSNFSCNALKALQKKGGIKGESFVCKNGASSTSVKLSSTSKSQSSQTTAKVSKSSSKAEEKKFTSGDIKAAASASSVSSSGASSSSSKSSKGNAAIMAPIGQTTPLVGLLTAIIMSIM
Protein: Chromatin-remodeling protein 11 (F4JAV9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MARNSNSDEAFSSEEEEERVKDNEEEDEEELEAVARSSGSDDDEVAAADESPVSDGEAAPVEDDYEDEEDEEKAEISKREKARLKEMQKLKKQKIQEMLESQNASIDADMNNKGKGRLKYLLQQTELFAHFAKSDGSSSQKKAKGRGRHASKITEEEEDEEYLKEEEDGLTGSGNTRLLTQPSCIQGKMRDYQLAGLNWLIRLYENGINGILADEMGLGKTLQTISLLAYLHEYRGINGPHMVVAPKSTLGNWMNEIRRFCPVLRAVKFLGNPEERRHIREDLLVAGKFDICVTSFEMAIKEKTALRRFSWRYIIIDEAHRIKNENSLLSKTMRLFSTNYRLLITGTPLQNNLHELWALLNFLLPEIFSSAETFDEWFQISGENDQQEVVQQLHKVLRPFLLRRLKSDVEKGLPPKKETILKVGMSQMQKQYYKALLQKDLEAVNAGGERKRLLNIAMQLRKCCNHPYLFQGAEPGPPYTTGDHLITNAGKMVLLDKLLPKLKERDSRVLIFSQMTRLLDILEDYLMYRGYLYCRIDGNTGGDERDASIEAYNKPGSEKFVFLLSTRAGGLGINLATADVVILYDSDWNPQVDLQAQDRAHRIGQKKEVQVFRFCTESAIEEKVIERAYKKLALDALVIQQGRLAEQKTVNKDELLQMVRYGAEMVFSSKDSTITDEDIDRIIAKGEEATAELDAKMKKFTEDAIQFKMDDSKGADFYDFDDDNKDENKLDFKKIVSDNWNDPPKRERKRNYSESEYFKQTLRQGAPAKPKEPRIPRMPQLHDFQFFNIQRLTELYEKEVRYLMQTHQKNQLKDTIDVEEPEGGDPLTTEEVEEKEGLLEEGFSTWSRRDFNTFLRACEKYGRNDIKSIASEMEGKTEEEVERYAKVFKERYKELNDYDRIIKNIERGEARISRKDEIMKAIGKKLDRYRNPWLELKIQYGQNKGKLYNEECDRFMICMIHKLGYGNWDELKAAFRTSSVFRFDWFVKSRTSQELARRCDTLIRLIEKENQEFDERERQARKEKKLAKSATPSKRPLGRQASESPSSTKKRKHLSMR
Protein: Flap endonuclease GEN homolog 1 (EC 3.1.-.-) (Q17RS7)
Organism: Homo sapiens (Human)
Function: Endonuclease which resolves Holliday junctions (HJs) by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation. Cleaves HJs by a nick and counter-nick mechanism involving dual coordinated incisions that lead to the formation of ligatable nicked duplex products. Cleavage of the first strand is rate limiting, while second strand cleavage is rapid. Largely monomeric, dimerizes on the HJ and the first nick occurs upon dimerization at the junction. Efficiently cleaves both single and double HJs contained within large recombination intermediates. Exhibits a weak sequence preference for incision between two G residues that reside in a T-rich region of DNA. Has also endonuclease activity on 5'-flap and replication fork (RF) DNA substrates.
Subcellular location: Nucleus {ECO:0000305|PubMed:26578604, ECO:0000305|PubMed:28049850}.
Interaction partners:
- Structure-specific endonuclease subunit MUS81
- Structure-specific endonuclease subunit EME1
- DNA replication ATP-dependent helicase/nuclease DNA2
- Structure-specific endonuclease subunit SLX4
- Structure-specific endonuclease subunit SLX1
- RecQ-mediated genome instability protein 1
- Double-strand break repair protein MRE11
- RecQ-mediated genome instability protein 2
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- DNA repair protein RAD51 homolog 1
Sequence:
MGVNDLWQILEPVKQHIPLRNLGGKTIAVDLSLWVCEAQTVKKMMGSVMKPHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHFKSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNFTMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILKGQSLLQRFNRWNETSCNSSPQLLVTKKLAHCSVCSHPGSPKDHERNGCRLCKSDKYCEPHDYEYCCPCEWHRTEHDRQLSEVENNIKKKACCCEGFPFHEVIQEFLLNKDKLVKVIRYQRPDLLLFQRFTLEKMEWPNHYACEKLLVLLTHYDMIERKLGSRNSNQLQPIRIVKTRIRNGVHCFEIEWEKPEHYAMEDKQHGEFALLTIEEESLFEAAYPEIVAVYQKQKLEIKGKKQKRIKPKENNLPEPDEVMSFQSHMTLKPTCEIFHKQNSKLNSGISPDPTLPQESISASLNSLLLPKNTPCLNAQEQFMSSLRPLAIQQIKAVSKSLISESSQPNTSSHNISVIADLHLSTIDWEGTSFSNSPAIQRNTFSHDLKSEVESELSAIPDGFENIPEQLSCESERYTANIKKVLDEDSDGISPEEHLLSGITDLCLQDLPLKERIFTKLSYPQDNLQPDVNLKTLSILSVKESCIANSGSDCTSHLSKDLPGIPLQNESRDSKILKGDQLLQEDYKVNTSVPYSVSNTVVKTCNVRPPNTALDHSRKVDMQTTRKILMKKSVCLDRHSSDEQSAPVFGKAKYTTQRMKHSSQKHNSSHFKESGHNKLSSPKIHIKETEQCVRSYETAENEESCFPDSTKSSLSSLQCHKKENNSGTCLDSPLPLRQRLKLRFQST
Protein: Golgi-associated RAB2 interactor protein 6 (Q8NEG0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEDCCMLPYYTAQSSPAMGMFNTSMGKLQRQLYKGEYTIFRYAPMFESDFIQISKRGEVIDVHNRARMVTMGIVRTSPCLTLPDVMLLARPAAVCDNARCGPATQKRESPPAEILELTRLLPLMFVKITIHNSVKKQLHLKLATGRSFYLQLCPPSDASEDLFVHWENLVYILRPPVEAYSDTRAILAGNTLDSSVLEEVQRSPVGYAMKFCEEKEQFRISRLHMNAEMFGSTYCDYTIEI
Protein: Metastasis associated family, member 3 (Metastasis-associated protein MTA3) (Q7ZUE1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAANMYRVGDYVFFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISQSLIQLADKHAKDLEEEKESPPESDLTEKQKHQLRHRELFLSRQYESLPATHIRGKCSVALLNETEVVLSYLEKEDTFFYSLVYDPTQKTPLADKGEIRVGPRFQADVPEMLQEGEADDRDQSKLEMKMWDPECPLTNKQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSALSVLVPQGGPVLCRDEMEEWSSSEANLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISVSNGKMATVNGAAAGTGSFHTAGGGRACESCFAVQSAQWYSWGPPNMQCRLCVSCWMYWKKYGGLKMPSRAEGAEEKTPPSPAPNESRSRGHCARQSSHMVPIRNSGSPKSSMKTKQAFLLQATRLTKLARHMCRDLIRLRRAARRPFVPINCGAIKAECKSSLNS
Protein: Ovulation-inducing factor (OIF) (J9PBR9)
Organism: Lama glama (Llama)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
APSHPIFHRGEFSVCDSVSVWVADKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVASGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSKKAS
Protein: N-alpha-acetyltransferase RimI (EC 2.3.1.255) (EC 2.3.1.258) (I6YG32)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues. Able to mediate acetylation of a wide variety of N-terminal residues, with preference for hydrophobic N-termini. Acetylates GroS/GroES and GroEL1. Able to acetylate the ribosomal protein S18, but it is unclear whether it acetylates its N-terminal alanine residue.
Interaction partners:
- Uncharacterized protein Rv3421c
- tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
- tRNA N6-adenosine threonylcarbamoyltransferase
- Alanine racemase
- Ribosomal-protein-alanine acetyltransferase RimJ
Sequence:
MTADTEPVTIGALTRADAQRCAELEAQLFVGDDPWPPAAFNRELASPHNHYVGARSGGTLVGYAGISRLGRTPPFEYEVHTIGVDPAYQGRGIGRRLLRELLDFARGGVVYLEVRTDNDAALALYRSVGFQRVGLRRRYYRVSGADAYTMRRDSGDPS
Protein: Hairy-related 8a (F1QI81)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTASNMGNGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQSKLEKADVLEITVQHMENLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLPLSPTQSPINLPSSLQPHALLLSPSPPSSPTHSLVRPREQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW
Protein: Sialyltransferase-like protein 2 (EC 2.4.-.-) (Q8RY00)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the transfer of 2-keto-3-deoxy-D-lyxo-heptulosaric acid (Dha) and/or 2-keto-3-deoxy-D-manno-octulosonic acid (Kdo) on the homogalacturonan backbone of rhamnogalacturonan-II. Required for efficient pollen grain germination and pollen tube elongation. Does not possess sialyltransferase activity in vitro.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:19470101}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Beta-1,6-galactosyltransferase GALT29A
- 2-dehydro-3-deoxyphosphooctonate aldolase 1
- 2-dehydro-3-deoxyphosphooctonate aldolase 2
- UDP-D-xylose:L-fucose alpha-1,3-D-xylosyltransferase MGP4
- At1g19710
Sequence:
MKLLHLIFLLALTTGISAVLIYIIGVSNLYESNRFTNEDLEALQSLQNGFQKCVSANGLGLQAAMGRDYCKVSINFPKDTVPKWKDPKSGELEGLSYEFDLCEAVATWEQVRNSSTILTKEYIDALPNGWEDYAWRRINKGIQLNRCQNKSLCIEKLSLVLPETPPYFPRQFGRCAVIGNSGDLLKTKFGKEIDTYDTVLRENGAPIQNYKEYVGEKSTFRLLNRGSAKALDKVVELDEKKQEVLLVKTTIHDIMNKMIREVPIKNPVYLMLGASFGSAAKGTGLKALEFALSTCDSVDMYGFTVDPGYKEWTRYFSESRQGHTPLHGRAYYQMMECLGLIKIHSPMRADPNRVVKWVPSRSTIRSARIAAEKLLRRVGAGSADPLASCSIVKKRNKNKRPMVSHLRKPVSDHQKFVRSTSMYPVEHSPGHGQLCITPAD
Protein: X-ray repair cross complementing 6 (A0A8I5ZXI9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSEWESYYKTEGEEEEEEEQSPDTNGEYKYSGRDSLIFLVDASRAMFESQGEDELTPFDMSIQCIQSVYTSKIISSDRDLLAVVFYGTEKDKNSVNFKSIYVLQDLDNPGAKRVLELDRFKGQQGKKHFRDTIGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDDPHGNDSAKASRARTKASDLRDTGIFLDLMHLKKRGGFDVSLFYRDIISIAEDEDLGVHFEESSKLEDLLRKVRAKETKKRVLSRLKFKLGKDVALMVGVYNLVQKANKPFPVRLYRETNEPVKTKTRTFNVNTGSLLLPSDTKRSLTFGTRQIVLEKEETEELKRFDEPGLILMGFKPMVMLKNHHYLRPSLFLYPEESLVNGFQLVFLPYADDKRKVPFTEKVMANPEQIDKMKAIVQKLRFTYRSDSFENPVLQQHFRNLEALALDMMESEQVVDLTLPKVEAIKKRLGSLADEFKELVYPPGYNPEGKIAKRKADNEGSASKKPKVELSEEELKDLFAKGTLGKLTVPALRDICKAYGLKSGPKKQELLEALSRHLEKN