wanglab/gogpt-training-data huggingface dataset:
Protein: Rootletin (Abnormal dye filling protein 14) (Chemotaxis abnormal protein 10) (Q09EF7)
Organism: Caenorhabditis elegans
Function: Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Required for cilia integrity and function in sensory neurons. Maintains cilia integrity, partly by modulating the assembly and transport of intraflagellar proteins along the ciliary axoneme. Required for normal mating behavior and normal responses to environmental and chemical stimuli.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:24094853, ECO:0000269|PubMed:27623382}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:24094853}.
Interaction partners:
- Crescerin-like protein che-12
- Intraflagellar transport protein 88 homolog
- Intraflagellar transport protein osm-1
- WD_REPEATS_REGION domain-containing protein
- Girdin homolog
- Intraflagellar transport protein che-13
- CHE-14 protein
Sequence:
MKSAASSEDVVRVTEDLSECRNRLDAGIEENRRNRQVIQDINDQLQRFRQRANAESIESFNLTPSPDVTLSSLAHPGLTHLHNQTNISMPSLTIDIPLNSNAMISSSRTPNYAINGLRNRHKSLVGHRYRSTSPIGDYGRHRSSPRVLAHYNLDGADIGVGEENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTETQHRKLISLWKEFTAVKRQLHELRTTTANDLDRQLTEFTRCATLMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVRFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYRNCAQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYSHKRKLLESQIQLLREQLEAERRKRTKGVVATGPTVSRRGVQHTSAFRHTIERHRSLSQSSERTILQERYLEYVYTGDRTPAIQMINTPPISPLSHSGSFNSDGREARIRRESDNGHLQH
Protein: Protein CDI (Protein CADMIUM INDUCED) (Q9XIP8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable nucleotide-diphospho-sugar transferase required for pollen germination and tube growth.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:22569258}.
Interaction partners:
Sequence:
MTISNGDVKSETCNNGSSEKKPFRIFVGYDPREDLAYQVCHHSITKRSSIPVEITPIIQSDLRKKGLYWRERGQLESTEFSFSRFLTPHLSDYQGWAMFVDCDFLYLADIKELTDLIDDKYAIMCVQHDYTPKETTKMDGAVQTVYPRKNWSSMVLYNCGHPKNKTLSPEIVNTQTGAFLHRFQWLEDEEIGSIPFVWNFLEGHNRVVEKDPTTQPKAVHYTRGGPWFDAWKDCEFADLWLNEMEEYNKENKKEADNAK
Protein: Elongation factor 1-beta 2 (EF-1-beta 2) (Elongation factor 1-beta' 2) (EF-1-beta' 2) (Elongation factor 1B-alpha 2) (eEF-1B alpha 2) (Q9SCX3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
Interaction partners:
- Probable elongation factor 1-gamma 2
- Probable elongation factor 1-gamma 1
- Translationally-controlled tumor protein 1
- Elongation factor 1-alpha 1
- Translationally controlled tumor protein 2
- Small ribosomal subunit protein uS2z
- Elongation factor 1-delta 2
- Ubiquitin carboxyl-terminal hydrolase 6
- Large ribosomal subunit protein uL11x
- Small ribosomal subunit protein eS1z
Sequence:
MAVTFSDLHTEEGVKSVEEHLAGKTYISGDQLSVDDVKVYAAVPVKPSDAFPNASKWYESVASQLAKSFPGKAVGVQFGGSAAAAPAVEAEAPAAAADDDDDMDLFGDETEEEKKAAEEREAAKKDTKKPKESGKSSVLMDVKPWDDETDMKKLEEAVRGVEMPGLFWGASKLVPVGYGIKKLTIMFTIVDDLVSPDNLIEDFLTSEPNNEYIQSCDIVAFNKI
Protein: Thiamine biosynthesis protein THI22 (Q06490)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Is not required for thiamine biosynthesis.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Thiamine biosynthetic bifunctional enzyme
- Protein PET18
- DNA polymerase alpha catalytic subunit A
Sequence:
MVIILLGLCTLGFPRTAFCPSIMTNSTVSINTPPPYLTLACNEKLPTVMSIAGSDSSGGAGVEADIKTITAHRCYAMTCVTTLTAQTPVKVYGAQNIPKKMVSQILDANLQDMKCNVIKTGMLTVDAIEVLHEKLLQLGENRPKLVIDPVLCAASDSSPTGKDVVSLIIEKISPFADILTPNISDCFMLLGENREVSKLQDVLEIAKDLSRITNCSNILVKGGHIPCDDGKEKHITDVLYLGAEQKFITFKGQFVNTTRTHGAGCTLASAIASNLARGYSLSQSVYGGIEYVQNAIAIGCDVTKKAVKVGPINHVYAVEIPLEKMLTDECFTASDAVPKKPIEGSLDKIPGGSFFNYLINHPKVKPHWDAYVNHEFVKRVADGTLERKKFQFFIEQDYLYLIDYVRVCCVTGSKSPTLEDLEKDLVIADCARNELNEHERRLREEFGVKDPDYLQKIKRGPALRAYCRYLIDISRRGNWQEIVVALNPCLMGYVYAVDKVKDKITAAEGSIYSEWCDTCASSFCYQAVLEGERLMNHILETYPPDQLDSLVTIFARGCELETNFWTAAMEYE
Protein: Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2) (rSec22a) (Q642F4)
Organism: Rattus norvegicus (Rat)
Function: May be involved in vesicle transport between the ER and the Golgi complex.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:8621431}; Multi-pass membrane protein {ECO:0000269|PubMed:8621431}.
Interaction partners:
- BET1 homolog
- Sec1 family domain-containing protein 1
- Synaptobrevin homolog YKT6
- Syntaxin-5
- Golgi SNAP receptor complex member 2
- Golgi SNAP receptor complex member 1
- BET1-like protein
- Syntaxin-6
- Protein transport protein SEC23
- Vesicle transport through interaction with t-SNAREs homolog 1A
Sequence:
MSMILSASVVRVRDGLPLSASTDCEQSAGVQECRKYFKMLSRKLAQFPDRCTLKTGRHNINFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQMEIKLRPPYQIPMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVAFILSLLCGALNLIRGFHAIESLLQSDGEDFSYMIAFFLGTAACLYQCYLLVYYTSWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQGKAPDHDV
Protein: Clathrin coat assembly protein AP180A (P38856)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in endocytosis and clathrin cage assembly.
Subcellular location: Bud {ECO:0000269|PubMed:9531549}. Bud neck {ECO:0000269|PubMed:9531549}. Cell membrane {ECO:0000269|PubMed:9531549}; Peripheral membrane protein {ECO:0000269|PubMed:9531549}; Cytoplasmic side {ECO:0000269|PubMed:9531549}. Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Actin cytoskeleton-regulatory complex protein PAN1
- Clathrin heavy chain
- EH domain-containing and endocytosis protein 1
- Epsin-1
- Epsin-2
- Protein SLA2
- Actin-regulating kinase PRK1
- Actin cytoskeleton-regulatory complex protein END3
- Actin-regulating kinase 1
- Clathrin light chain
Sequence:
MTTYFKLVKGATKIKSAPPKQKYLDPILLGTSNEEDFYEIVKGLDSRINDTAWTIVYKSLLVVHLMIREGSKDVALRYYSRNLEFFDIENIRGSNGSASGDMRALDRYDNYLKVRCREFGKIKKDYVRDGYRTLKLNSGNYGSSRNKQHSINIALDHVESLEVQIQALIKNKYTQYDLSNELIIFGFKLLIQDLLALYNALNEGIITLLESFFELSHHNAERTLDLYKTFVDLTEHVVRYLKSGKTAGLKIPVIKHITTKLVRSLEEHLIEDDKTHNTFVPVDSSQGSAGAVVAKSTAQERLEQIREQKRILEAQLKNEQVAISPALTTVTAAQSYNPFGTDSSMHTNIPMAVANQTQQIANNPFVSQTQPQVMNTPTAHTEPANLNVPEYAAVQHTVNFNPVQDAGVSAQQTGYYSINNHLTPTFTGAGFGGYSVSQDTTAASNQQVSHSQTGSNNPFALHNAATIATGNPAHENVLNNPFSRPNFDEQNTNMPLQQQIISNPFQNQTYNQQQFQQQKMPLSSINSVMTTPTSMQGSMNIPQRFDKMEFQAHYTQNHLQQQQQQQQQQQQQQQQQPQQGYYVPATAGANPVTNITGTVQPQNFPFYPQQQPQPEQSQTQQPVLGNQYANNLNLIDM
Protein: Cyclin (Q4Q9U4)
Organism: Leishmania major
Interaction partners:
- cyclin-dependent kinase
- cyclin-dependent kinase
- Cyclin-dependent kinases regulatory subunit
- Protein kinase domain-containing protein
- Putative cell division cycle protein
- Uncharacterized protein
- Uncharacterized protein
- TROVE domain-containing protein
- Putative serine/threonine protein kinase
- Putative serine/threonine-protein kinase
Sequence:
MAVPLRMRIPFSNQTNLVREPYHKPAAQPPTPLTNESRFVSEYGSEILTYFLEVERVVYSERMYIDRQSEVTDRMRKILIDWLVDVVTEFKLHPETFFLAVDIIDRFLFFYSIPRTKLQLVGVTAILVAAKHEEIWPPTVNDCVAVTANTYTSREVIDMEFDVVTTLRFKFTVPTTYPITCRLLESCHMAPAVCHATFLFLESAAHCYPLLQFLPSRIAAGAVLLGAFLIRYNRSKGAISLQGLWEIEVSPFAQGIGFDELQPVTEQLLPFTQRLCSGSSRLQAVRRKYSSSEYDCVASLEFPFISTSA
Protein: Uncharacterized protein (Q387C8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSHTMTNASTLMSITVCDPNMKGTGLEMECLRPSMHIPELVLIPPIYVLIISGFLCTLVNAFFNYVSFGRSSITTAMEKHTRVKMLIHHSLIVRDMEGHTSVSRRDNIYNETDHLLTHSNVSVDHNDSAVFFQGILNSDALGFESPRVPASVADEALYGSLECIRRVGQQIVFSHNPKYMIISITKSLVMLLVLQYHFDYNGGWDRFVVCTAANLMSGLLTPVLEYGAEFLLQLDPDSNLKVAQEHDELDDVVLISRILTRIGEFKLEDLETVLVQGCTFIVFGAVLLPPVFVFCLVGAAMFLWLFGPLWFAYGYFRHLYYKPRQSKGLSSPNARGWLRITPFRELARIVLLKAVTLFLLQWTVQCSFLLGLMLLQGESYLKALHLEVKHQLWRWNNPLKMGGFRLLCLVSQLLF
Protein: Quinoprotein amine dehydrogenase, beta chain-like RIC1-like guanyl-nucleotide exchange factor (F4K735)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Immunoglobulin
- Cysteine-rich repeat secretory protein 42
- Cysteine-rich repeat secretory protein 54
- Serine protease inhibitor
- Putative serpin family protein)
- Serpin-Z4
- Serpin-Z3
- Serpin-Z2
- Serpin-Z10
- Esterase/lipase/thioesterase family protein
Sequence:
MYMAYGWPQVIPLLPGSCPSSQRVVYLKLAGRLLLVVSPSHLELWGSSQQRVRLGKYMRDDKSVREEGENLQAVWSPDAKLIAVLTSSFFLHIYKIKFTDKRVKPGERQPSELCFATISLLLSEQVPFAGKDLSVSNFVRDSKTMLLGLSDGSLYSISWKGEFGGAFSIGSHPSDSNDDRLLSYTLGNGLVSGVASPTLASDDKFSTNPAIVQLELCTRSKLLFVLNSDGQLVVCSVNKKGLKYTESIRAEKKVGGDAVCASVASEQQILAVGTRKGMVELYDLSHSISLLRTVSLHDWGYSADYTGPVNNIAWTPDNSAFAVGWKSRGLAVWSVSGCRLMSTVRQIGLTSTSSPKINPKQDCKYEPLMSGTSAIQWDEYGYRLFATEEASYDRILAFSFGKCCLNRGVSGKTYVRQVMYGDDRLLMVQAEDTDELKLLHLKLPVSYISQNWPVQHVAASEDGKYLAFAGLHGLILYDIRFKKWRVFGDVSQEQQIHCKGLLWLGKIVVICNYIEASETYELLFYPRYHLDQSSLLCRKVLLGKPMVMDVYQDYILVSYLPFFIHVYHVKIYGELTPSSKADLQLSTVRELSIMTAKSHPAAMGFVPDQHLREGELDNDNLSSDLSDREPSRCLILRGNGELSLLDLVDGRERELTDSVELFWVTCGQSEEKTNLVEEVSWLDYGHRGMQVWYPSLGDDPFMQEDFLQLDPELEFDREVYPLGLLPNVGVVVGVSQRMSFSASAEFACFEPTPQAQTILHCLLRHLLQRDKNEEALLLAQLSAEKPHFSHCLEWLLFTVFDAEISRPNPNRNQISGPGHLKKLSLLRKACDLIKKFPEYYDVVVNVARKTDARHWADLFSAAGISTTLFEDCFQRRWYRTAACYILVIAKLEGVAVSQYCALRLLQATLDESLYDLAGELVRFLLRSGRDIEQAPTESDSLSPKLLGFLIFGSSHKKSSLDKSSSFKEQSPHVASVKSILESHASYLMSGKELSKLVAFVKGTQFDIVDFLQRERYGCAQLQNFAAGLELIGQKLQMSELQNRLDAEFLLAQMCSVKFKEWIVVLATLLQRSEVLYDIFRYDLRLWKAYSVTLESHLAFAHYHDLLQILEAKLSATSREESNRGSIS
Protein: Myogenic factor 5 (Myf-5) (P24699)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
Subcellular location: Nucleus.
Interaction partners:
- Paired box protein Pax-7
- Myogenic factor 6
- Paired box protein Pax-3
- Transcription factor E2-alpha
- Myocyte-specific enhancer factor 2C
- Growth/differentiation factor 8
- Transcription factor 4
- Myocyte-specific enhancer factor 2A
- Myocyte-specific enhancer factor 2D
- Cadherin-15
Sequence:
MDMTDGCQFSPSEYFYEGSCIPSPEDEFGDQFEPRVAAFGAHKAELQGSDDEEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKNSSFDSIYCPDVSNACAADKSSVSSLDCLSSIVDRITSTEPSELALQDTASLSPATSANSQPATPGPSSSRLIYHVL
Protein: Profilin (PfPfn) (P86294)
Organism: Plasmodium falciparum (isolate HB3)
Function: Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P07274}.
Interaction partners:
Sequence:
MAEEYSWDSYLNDRLLATNQVSGAGLASEEDGVVYACVAQGEESDPNFDKWSLFYKEDYDIEVEDENGTKTTKTINEGQTILVVFNEGYAPDGVWLGGTKYQFINIERDLEFEGYNFDVATCAKLKGGLHLVKVPGGNILVVLYDEEKEQDRGNSKIAALTFAKELAESSQ
Protein: TATA-box binding protein associated factor 15 (A0A075B7F2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQVIHSPMVVMRIKSRAHIASNHIITRDSSKTWNHQEAKVEEHLPMTSQTMVNKIHMTSSQAMINIKAHMMSSQIMISSMIPIVKTSSPIIHKGKTTATTHKMTVVM
Protein: Paired box 3 (Paired-box transcription factor protein PAX3) (Q8QGS3)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Myogenic factor 5
- Myoblast determination protein 1 homolog
- Transcription factor SOX-10
- Myogenin
- Nuclear receptor coactivator
- Myogenic factor 6
- Forkhead box protein D3
- Zinc finger protein ZIC 1
- Transcription factor SOX-9
- Uncharacterized protein.
Sequence:
MTTLAGAVPRMMRPGAGQSYPRGGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENAGMFSWEIRDRLLKDGVCDRNTVPSVSSISRILRSKFGKGEEEEAELERKEAEEGDKKAKHSIDGILSERASAAQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPSAMPTLPTYQLSEPSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSSLPSNPESSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSAFHYLKPDIA
Protein: DIS3-like exonuclease 2 (EC 3.1.13.-) (Protein SUPPRESSOR OF VARICOSE) (P0DM58)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3' (Probable).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03045, ECO:0000269|PubMed:20798041}. Cytoplasm, P-body {ECO:0000305|PubMed:20798041}.
Interaction partners:
Sequence:
MKSASSEQSVERIENGHKKKRNRPQKQNRRSKQSSVPIEDAHVEESLDGRDSSRSKAKDSTSSSKQQRPNTDELEAMRASNVAFNSMPPMRAESGYPRRSASPLLSSPEVSKQLLSKSCPDPRACEQSPGMNGELFQQIEGSSQRKIFSSHWSLDAVTEALEKGEAFKALFRVNAHNRNEAYCKIDGVPTDILINGNVCQSRAVEGDTVVIKLDPLSLWPKMKGFVTESAAKPEGTNSPPEKDDKKARQKNGIDVVEGFEDGFSKNKSSVIGKGAKNGVTPSSPPSLDSCLGSFCEQKGNCSAVDKLCGILSSFPHKRPTGQVVAVVEKSLVRDSIVGLLDVKGWIHYKESDPKRCKSPLSLSDDEYVQLMPADPRFPKLIVPFHVLPGSIRARLENLDPNLEAELVAAQIVDWGEGSPFPVAQITHLFGRGSELEPQINAILYQNSVCDSDFSPGSLTSLPRVPWEVPEEEVQRRKDLRDLCVLTIDPSTATDLDDALSVQSLPGGFFRVGVHIADVSYFVLPETALDTEARFRSTSVYLMQRKISMLPPLLSENVGSLSPGADRLAFSILWDLNREGDVIDRWIGRTIIRSCCKLSYDHAQDIIDGKSDVAENGWPALHGSFKWCDVTRSVKQLSEISTTLRQKRFRNGALQLENSKPVFLFDEHGVPYDFVTCSRKGSNFLVEEFMLLANMTAAEVISQAYPASSLLRRHPEPNTRKLKEFEGFCSKHGMDLDISSSGQLQDSLEKITGNLKDDSVFVDILNNYAIKPMQLASYFCTGNLKDSVAEWGHYALAVPLYTHFTSPLRRYPDIVVHRALAAALEAEELYSKQKQTAIDEGRSCFTGIHFNKDAAESIEGKEALSVAALKHGVPSTEILSDVAAYCNERKLAARKVRDACDKLYTWFVLKQKEIFPCEARVMNLGSRFMTVYISKLGIERRIYYDQIEGLCADWLEATSTLIVDKLYSKRGGRGFFKPMKEAVYLVSPCEVCVAKCSALSVHDTESPEAVSIDEVAPAVFPLTIQLFSTIPVVLHAVGGDDGPLDIGARLYMSSYY
Protein: Proline-serine-threonine phosphatase interacting protein 1 (H0YKF1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XDAGRLQHRRRHRQFHPGQEHGHRAPRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL
Protein: Leucine-rich repeat and transmembrane domain-containing protein 1 (Q8BXQ3)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLNEGLCCGAWAMKGTLLLVSSVGLLLPGVGSCPMKCLCHPSSNSVDCSGQGLSKVPRDLPPWTVTLLLQDNRIHWLPALAFQSVSLLSTLNLSNNSLSNLAAEAFYGLPHLRVLNVTQNSLLSIESSFAHALPGLRELDLSSNSLRILPTSLGKPWENLTVFAVQQNHLLHLDRELLEAMPKVRLVLLKDNPWICDCHLLGLKLWLERFTFQGGETDGAICRLPEPWQGKALLSIPHELYQPCSLPSQDLAPSLVQQPGSAPQDAQKSHENSSGQQDPLECEAKPKPKPTNLRHAVATVVITGVVCGIVCLMMLAAAIYGCTYAAITAQYQGRPLASARKSEKMGSKELMDSSSA
Protein: MATH domain and coiled-coil domain-containing protein At3g58380 (RTM3-like protein At3g58380) (Q9M2H8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEKEVDKKFVWVIKDLNVFYPKQSHSDPFLIAGSRWRLLALPKGTNYEFFYQYMGVADSCQSLTSSWRRHVKLRLTIVNGISHKRSIVTDSDLYFDENLPACSYPTVPPPFNLLARDAGFLICREITIVIEVVSLEVIGTSNNDGANSIDLLKQTQQIIDVNGFQVLPSQVESVKRIFEIYPNIASEVPSMKPCLKTLYMNVLLGIIETLCQLPAELSDTDLDEASIAVLFVSQGGFKVDWLEKKLKEVKEKKKNVDNGKARLQQIEEDLQKLNQKRLDLKDILDKEKANDLTANVPLSFNDVLKMF
Protein: U3 small nucleolar ribonucleoprotein protein IMP3, putative (Q382E4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- PIN domain-containing protein
- U3 small nucleolar RNA-associated protein 18
- AATF leucine zipper-containing domain-containing protein
- Nrap protein domain-containing protein
- Bystin, putative
- Small-subunit processome Utp21 domain-containing protein
- KRR1 small subunit processome component
- Bms1-type G domain-containing protein
- U3 small nuclear ribonucleoprotein
- U3 small nucleolar RNA-associated protein 6 N-terminal domain-containing protein
Sequence:
MVRDTSRHVSVVKSRPTKEAVKEQETALKRSKRSKFTPKSSHSKGNPIHRTLKYHEKKLLRKHDFMQYPQDNWHEPFCITKYHLEDREDYRRYLRLVGLIRQLLTHLRYLPADSKIRIQITQQILDKLYAMGLINEKLGLAEVDKVGVEVFCKRRLPTVLRDLNMAPNCKIAADFVHHGHVRVGTSQIRDPAFLVPRDLEDYVTWMPGSKVKQHVDTFNVQRDDYE
Protein: Antigen Lp49 (Leptospiral 49 kilodalton protein) (Lp49) (Q72U69)
Organism: Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Function: May be involved in virulence. Binds human plasminogen (PLG) and stimulates its proteolytic cleavage to enzymatically active plasmin in the presence of an urokinase-type PLG activator in vitro. Activated plasmin has proteolytic activity which may help the bacteria to spread throughout the host by degrading extracellular matrix components, facilitating tissue penetration and invasion.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:17609931, ECO:0000269|PubMed:20582320}.
Interaction partners:
Sequence:
MNSNPKKKFLKLIKIKSDIILLIPIFLFLVCCKSGDFSLLSSPINREKNGTEIVKFSIHPYKGTVIRLGEEILPFKVLEMDKNIALVEMAIPVYKDEKEIELKLSSPGFQNSSYRIRKPEELNEKLIALDKEGITHRFISRFKTGFQPKSVRFIDNTRLAIPLLEDEGMDVLDINSGQTVRLSPPEKYKKKLGFVETISIPEHNELWVSQMQANAVHVFDLKTLAYKATVDLTGKWSKILLYDPIRDLVYCSNWISEDISVIDRKTKLEIRKTDKIGLPRGLLLSKDGKELYIAQFSASNQESGGGRLGIYSMDKEKLIDTIGPPGNKRHIVSGNTENKIYVSDMCCSKIEVYDLKEKKVQKSIPVFDKPNTIALSPDGKYLYVSCRGPNHPTEGYLKKGLVLGKVYVIDTTTDTVKEFWEAGNQPTGLDVSPDNRYLVISDFLDHQIRVYRRDGF
Protein: Uncharacterized protein (O53923)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Soluble secreted antigen MPT53
- Probable conserved integral membrane protein
- Protein DipZ
- Alkyl hydroperoxide reductase E
Sequence:
MACPEWEISRSKRTRKPVLRPRHSVSTLTNRFLAEFCHRYGIGVPTRLARGATVPTRRLQDINDQPVDVPAATGRTHLQFRRFAACPICHLHLRSFANRHQEVADSGITEVVFFHSAADALRGYQSLLPFAVIADPDRVQYREFGVEKSLGAITHPRALWAAVRGSAAMLHRNDPERAGVGFGDGTTHLGLPADFLLDADGTVAAVHYGRHADDQWSVDQLIDINRSLGGKGTQ
Protein: Pfmc-2TM Maurer's cleft two transmembrane protein (Q8IBW5)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MFHYFYKVYIFTIIICASNLFNNDGVEIGTYKLSYHNGGRQFRMLAQKNENEKSNGNTLKNTLLKDENKKGSKTKKLDPQITSLVNLVDNMDINEEQKDKIKTLTLEYINSDDIKKKNKSINELKKYSNNEECKEHMNNYLMHLRMQNEIKYLKRKNFWNNIWIVVITLLSIILLIAAMAMNTFPGFSAFLVTFVLSNLMIYMFARFYPEIKVQFKKFKETCTNLFKKKSK
Protein: Photosystem II reaction center protein L (PSII-L) (Q2LIK6)
Organism: Oryza officinalis
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Plastid, chloroplast thylakoid membrane {ECO:0000256|HAMAP-Rule:MF_01317}; Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01317}.
Interaction partners:
Sequence:
MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
Protein: Protein ripply1 (Q0D2K3)
Organism: Homo sapiens (Human)
Function: Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q2WG80}.
Interaction partners:
- TLE family member 5
- Transducin-like enhancer protein 1
- Transducin-like enhancer protein 2
- Transducin-like enhancer protein 4
- Transducin-like enhancer protein 3
Sequence:
MDSAACAAAATPVPALALALAPDLAQAPLALPGLLSPSCLLSSGQEVNGSERGTCLWRPWLSSTNDSPRQMRKLVDLAAGGATAAEVTKAESKFHHPVRLFWPKSRSFDYLYSAGEILLQNFPVQATINLYEDSDSEEEEEDEEQEDEEEK
Protein: Ribosomal biogenesis factor (Q8N0T1)
Organism: Homo sapiens (Human)
Function: Trans-acting factor in ribosome biogenesis required for efficient 40S and 60S subunit production.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:26711351}.
Interaction partners:
Sequence:
MAKNKLRGPKSRNVFHIASQKNFKAKNKAKPVTTNLKKINIMNEEKVNRVNKAFVNVQKELAHFAKSISLEPLQKELIPQQRHESKPVNVDEATRLMALL
Protein: Protein THEMIS (Grb2-associating protein) (Gasp) (Protein thylex) (Thymocyte-expressed molecule involved in selection) (Q8BGW0)
Organism: Mus musculus (Mouse)
Function: Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19597497, ECO:0000269|PubMed:19597498, ECO:0000269|PubMed:19620281}. Nucleus {ECO:0000269|PubMed:19597498, ECO:0000269|PubMed:19620281}.
Interaction partners:
- Growth factor receptor-bound protein 2
- Linker for activation of T-cells family member 1
- Protein TESPA1
- COP9 signalosome complex subunit 2
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 8
Sequence:
MALSLEEFVYSLDLRTLPRVLEIQSGIYFEGSVYEMFGNECCLSTGEVIKITGLKIKKMMAEICEGAIGGCESQKPFELPMNFPGLFKVMADKTPYLSIEEITRTVNIGPSRLGHPCFYHLKDIKLENLIIKQGEPIRFNSVEEINGETLVNCGVVRNHQSHSFTLPLSQEGEFYECEDEHIYTLKEIVEWKIPKNRTRTVKLTDFSNKWDSTNPFPEDFYGTLILKPVYEIQGVLKFQKDIVRILPSLDVEVKDITDSYDANWFLQLLSTDDLFEMTSKEFPVVAEVVEISQGNHLPQSILQREKTIVIHKKYQASRILASEIRSNFPKRHFLIPISYKGKFKRRPREFPTAYDLQIAKSRKETLHVVATKAFHTLHKELSPVSVGDQFLVHHSETTEVVFEGTRKVNVLTCEKVLNKTREDAQLPLYMEGGFVEVIHDKKQYQISELCTQFCWPFNVKVAVRDLSIKDDILAATPGLQLEEDITDSYLLISDFANPEECWEIPMSRLNMTVRLVNGSSLPADAGLLQVRSFVEEITEEQYYMMRRYESSLSHPPPRPPKHPSAEEMKLTLLSLAEERTINLPKSLKSHHVDRPKKLPSDESGQDSRAPVGFQNDVADVERQKSKHGPLQPQAPL