wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized exonuclease C637.09 (EC 3.1.-.-) (O94443)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable oligoribonuclease
- RNA exonuclease 3
- mRNA degradation protein pet127
- Exosome complex component rrp4
- Fluoride export protein 1
- Ribonuclease Z 1
Sequence:
MSKMGSSSMGELQDGITQEDSIEKKSKNVASHGEKRKVKRKKEDLSMDGSNDGVKDSPDSNDDSQSKKKKKKKLKKSQQPLNEENYPRLQTTENNLQKPLKISDLQELVFWCLADGQAPSWVLVRNKQMIHRAVILLVPGLEPSQFGFQPVRGNKHSFLLPNLLNENGPIQLPDFCEVFDRAWPTRSPGDRFRVFSPVNAFLQSPLSNEQKKKRDKETRAMASFSKPSDYLMSYESFIEDEYPLHPTVMKGEEVTQPSGWVASAGDFHSPPINPKILAIDCEMVRTENGLEIARVTIVDMKSEVIYDEFVKPESPVTDYVTQYSGITEEKLRNVTTVLSDVQSYLKKTVDNNTVLLGHSLNSDLNCLKFTHPHIIDTANIYNHTRGPPSKPSLKWLATKWLRREIQKAGALGHDSAEDALACVDLLKLKVKNGPAFGLFNQDFESIFHRLSRQQPTPLIGAIADYGNPESCIGKAAHKSVSCANDDEVVSAVVSLSDMHNFVWGRFRELEHAAMWNANRNTKQENNSDTDTENDSVEEDQVTSYSSALERFNRRIRLLYDSLPKGSLLLLYTGTGNPIEMSKLNAIRQQFRKEYQTKKWDELSVKWTDEENMKYISAVENTRNGLSFMTIK
Protein: Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member) (F1QXZ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU361195}. Nucleus {ECO:0000256|RuleBase:RU361195}.
Interaction partners:
- Mothers against decapentaplegic homolog.
- receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- receptor protein serine/threonine kinase
- SMAD family member 4.
- Mothers against decapentaplegic homolog
- Mothers against decapentaplegic homolog.
- Receptor protein serine/threonine kinase
- Mothers against decapentaplegic homolog 5
- Mothers against decapentaplegic homolog.
Sequence:
MHSSTSITSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMEELEKALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALDCCEFPFGSKQKEICINPYHYRRVETPVLPPVLVPRHSEFNPQHSLLAKFRNASLHNEPLMPQNATFPDSFPAMPCSSFSSSPSSSLNPSPAAHSFPNSPSSATEPGSPYQITAETPPPPYSMMESSPSEDVKPAESSENKLILTAPQRDLRPVCYEEPEYWCSVAYYELNNRVGETFHASARSILVDGFTDPSNNKNRFCLGLLSNVNRNSTIEHTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYQHGFHPTTVCKIPSGCSLKIFNNQLFAQLLSQSVNHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Protein: Enhancer of mRNA-decapping protein 4 homolog (Q9VKK1)
Organism: Drosophila melanogaster (Fruit fly)
Function: In the process of mRNA degradation, seems to play a role in mRNA decapping. Required for silencing a subset of endogenous miRNA targets.
Subcellular location: Cytoplasm, P-body {ECO:0000269|PubMed:17901217, ECO:0000269|PubMed:18755833}.
Interaction partners:
- Decapping protein 1, isoform A
- Enhancer of mRNA-decapping protein 3
- m7GpppN-mRNA hydrolase
- ATP-dependent RNA helicase me31b
- Protein associated with topo II related - 1, isoform A
- 5'-3' exoribonuclease 1
- U6 snRNA-associated Sm-like protein LSm1
- LD36341p
- CHK domain ov1
- Trailer hitch, isoform H
Sequence:
MLIALFALAHLPIFRKTPLSASSSPPPSVHRSPRCGKASTAYHPPPADACISITASAIDAASGMSNSAEQDKPIAANGNAAEPQEIEVIHFQAQEKQCCRVIRSNKTKVLTSGGVHTRGSSKVKLKNIVDYKWERKYYYPGHLVAVHRDGKHLAYAINVNNKATGMEGMVRVCNIATSMRALIKGMSGEVLDLQFAHTDCERILAVIDVSSLFVYKVDQIEGNLLCNLVLKVEDPIANYVPEYDMVSWCPYVCSSSATVPINDDDDENQLLIWSRSSQFQCFQVKMIVSEHGRGKIQPAALESGYLKIEEDSLITCAALSPDGTTVAAACADGLVRFYQIYLFDVRNHRCLHEWKPHDGKKVCSLFFLDNINKPVEESYWQHVITTSDANTEIKLWNCSLWKCLQTINVVASPSSLQPRNFIAGIDRSANYLVLSCLDSLAVYVMQIGSTGGADSENRSSDSEGEGCDTSKRIQNVAEFKLSSGILSFSIVNASMRRVKNSIESYYPIEEPDDFDDDSNSTSALVLHMFVVQAKSLQECQIIYQPCVAEKTERSSLNSKRSQTPEDNLLIKEEPESPNSGTVGAVQLDALFAKSAKRASTGSSSAMVAVAAAAAAAPSAILQDATKEAAKSESPQLSSAYTQQVNLMTPDAFSASGTAAAAAVFVSTSTTTSIGTDSSTTTSGQDRSIDSAVLQTIRMLATVTSKTSENPNAEVLLNLMNNTLIEDREQQKLKEKLDARKKFIAIDRNPERNVAENLASGSSSPSREVQEIMATQDDADAYEAELENLDDDDDDEEEELANSSPLPEAVDGTWPIVKLSSHSAELQNAAQIMSQAVQNTNNGNVPPTLGGGHNNNTSVGSNSNNNTATTLSTSNTSSSNNAGGTCVDSSGTGELNAKMELLIDLVKAQSKQINKLENEVNKLQKQQEAAAALHSKQDTSLEPKNLSQLAYKIEMQLSKLMEQYLKRYENEHKKKLTEFLAARESQNRELRDSVLQVLNQYVMNHFTDIIGNVLNMELQRQLLPRVNANMDQLQAQMQVEIVQKLSVFDKTVKENIAQVCKSKQFLDTFGKSVLIGVQTSLQTAFIESMSSTLIPAYEKSSQNMFKQLHDAFSVGIKDFMVQFNTYLQHMPQPQAGSGNTEEINNKLSMLKQLVESSLHKHRTELTDAMLETQREVKSLEILLARQVQETIRAELRKHMEAQNVAMRSQAATPAPPYDLRDSIKQLLMAGQINKAFHQALLANDLGLVEFTLRHTDSNQAFAPEGCRLEQKVLLSLIQQISADMTNHNELKQRYLNEALLAINMADPITREHAPKVLTELYRNCQQFIKNSPKNSQFSNVRLLMKAIITYRDQLK
Protein: RRM domain-containing protein (D5MCQ4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MNASSAPQQQQQQQQPQQGQAPQQQQQGPPQHQYQQQRPFHGTNLYIRGLMPNTNDDLLREMCSKYGNIASTKAIMDKATNNCKGYGFVDFESPQAAAAAVDGLNTEGVQAQMAKLQQQEQDPTNLYIANLPLDFTEQMLETELNKFGMVISTRILRTPDNQSRGVGFARMDSKEKCEVIISALNGGRFDTMSKEGPALLIKQADTGRKSKHSMNNPEMLQRMQYPQVYQSYYGYHPAAVYQQHYDVNSLASQMGGMHVGGGNPQANGGGDMYGAHMYGQNAGGQGGQGVGQGGQGGNQQFYNPNNGRNKKPMNPQ
Protein: Uncharacterized protein (Q8HCM2)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, putative, expressed
- Cytochrome c oxidase subunit 3
- NAD
- NAD
- Os01g0775100 protein
- NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial, putative, expressed
- Os05g0509200 protein
- NADH dehydrogenase iron-sulfur protein 2
- Cytochrome c oxidase subunit 1
Sequence:
MSLPGTSSFIGEFLILVGAFQRNGKVRNFPYHYFRECEDFVTFLHFFLYTSGVALSAGELLFLDQNLPPVDEAPPSREILDLDLNAPLPDPEPEVEIVPGDDQHVPPIQEDNPITFHLQNDEQRESLEQMLHSVKERCIMKLRNELIVNKRSRKWGSTKF
Protein: Lipolysis-stimulated lipoprotein receptor (Angulin-1) (Q86X29)
Organism: Homo sapiens (Human)
Function: Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity). Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:21245199}; Single-pass type I membrane protein {ECO:0000255}. Cell junction, tight junction {ECO:0000269|PubMed:21245199, ECO:0000269|PubMed:23239027}. Note=Located at tricellular contacts. {ECO:0000269|PubMed:21245199}.
Interaction partners:
- MARVEL domain-containing protein 2
- Apolipoprotein B-100
- Apolipoprotein E
Sequence:
MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
Protein: Melanoma antigen recognized by T-cells 1 (MART-1) (Antigen LB39-AA) (Antigen SK29-AA) (Protein Melan-A) (Q16655)
Organism: Homo sapiens (Human)
Function: Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Subcellular location: Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Interaction partners:
- Melanocyte protein PMEL
- Tyrosinase
- G-protein coupled receptor 143
- L-dopachrome tautomerase
- HLA class II histocompatibility antigen, DR alpha chain
- HLA class II histocompatibility antigen, DRB1 beta chain
- 5,6-dihydroxyindole-2-carboxylic acid oxidase
- Membrane-associated transporter protein
- Transient receptor potential cation channel subfamily M member 1
- Protein-cysteine N-palmitoyltransferase HHAT
Sequence:
MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP
Protein: Guanylin (Guanylate cyclase activator 2A) (P28902)
Organism: Rattus norvegicus (Rat)
Function: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Subcellular location: Secreted.
Interaction partners:
- Guanylyl cyclase C
- Guanylate cyclase activator 2B
- Guanylate cyclase 2D
- Transmembrane and immunoglobulin domain-containing protein 1
- cGMP-dependent protein kinase 2
Sequence:
MNAWLLSVLCLLGALAVLVEGVTVQDGDLSFPLESVKQLKHLREVQEPTLMSHKKFALRLPKPVAPELCSQSAFPEALRPLCEKPNAEEILQRLEAIAQDPNTCEICAYAACTGC
Protein: Presenilin (EC 3.4.23.-) (F7AGU8)
Organism: Macaca mulatta (Rhesus macaque)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasmic granule {ECO:0000256|ARBA:ARBA00004463}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004520}. Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU361148}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361148}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU361148}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361148}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
- Gamma-secretase subunit PEN-2
- Nicastrin
- Presenilin
- Gamma-secretase subunit APH-1
- Gamma-secretase subunit APH-1
- Amyloid-beta precursor protein
- Neurogenic locus notch homolog protein 1
- Catenin beta-1
- Glycogen synthase kinase-3 beta
- Neurogenic locus notch homolog protein 3
Sequence:
MTELPAPLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
Protein: Galactarate dehydratase (L-threo-forming) (GalcD) (EC 4.2.1.42) (P39829)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).
Interaction partners:
- Glucarate dehydratase
- 5-keto-4-deoxy-D-glucarate aldolase
- 2-hydroxy-3-oxopropionate reductase
- Glucarate dehydratase-related protein
- Probable galactarate/D-glucarate transporter GarP
- Probable galactarate/D-glucarate transporter GudP
- Altronate oxidoreductase
Sequence:
MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
Protein: Lipoxygenase 6, chloroplastic (AtLOX6) (EC 1.13.11.12) (Q9CAG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity). 13S-lipoxygenase that can use linolenic acid as substrates.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Allene oxide synthase, chloroplastic
- Probable inactive linolenate hydroperoxide lyase
- Alpha-dioxygenase 1
- Alpha-dioxygenase 2
- Phospholipase A
- Allene oxide cyclase 4, chloroplastic
- Triacylglycerol lipase SDP1L
- Allene oxide cyclase 2, chloroplastic
- Allene oxide cyclase 1, chloroplastic
- Allene oxide cyclase 3, chloroplastic
Sequence:
MFVASPVKTNFNGVSLVKSPAFSALSCRKQHRVPISRQVRAVISREEKAVDQEDGKKSTNKPLINSSQFPWQRSKYTGSKTVTAVVKIRKKIKEKLTERFEHQLELFMKAIGQGMLIQLVSEEIDPETGKGRKSLESPVMGLPKAVKDPRYLVFTADFTVPINFGKPGAILVTNLLSTEICLSEIIIEDSTDTILFPANTWIHSKNDNPQARIIFRSQPCLPSETPDGIKELREKDLVSVRGDGKGERKPHERIYDYDVYNDLGDPRKTERVRPVLGVPETPYPRRCRTGRPLVSKDPPCESRGKEKEEFYVPRDEVFEEIKRDTFRAGRFKALFHNLVPSIAAALSNLDIPFTCFSDIDNLYKSNIVLGHTEPKDTGLGGFIGGFMNGILNVTETLLKYDTPAVIKWDRFAWLRDNEFGRQALAGVNPVNIELLKELPIRSNLDPALYGPQESVLTEEIIAREVEHYGTTIEKALEEKRLFLVDYHDILLPFVEKINSIKEDPRKTYASRTIFFYSKNGALRPLAIELSLPPTAESENKFVYTHGHDATTHWIWKLAKAHVCSNDAGVHQLVNHWLRTHASMEPYIIATNRQLSTMHPVYKLLHPHMRYTLEINARARKSLINGGGIIESCFTPGKYAMELSSAAYKSMWRFDMEGLPADLVRRGMAEEDSSAECGVRLVIDDYPYAADGLLIWKAIKDLVESYVKHFYSDSKSITSDLELQAWWDEIKNKGHYDKKDEPWWPKLNTTQDLSQILTNMIWIASGQHAAINFGQYPFGGYVPNRPTLLRKLIPQETDPDYEMFMRNPQYSFLGSLPTQLQATKVMAVQETLSTHSPDEEYLIELREVQRHWFQDEQVVKYFNKFSEELVKIEKTINERNKDKKLKNRTGAGMPPYELLLPTSPHGVTGRGIPNSISI
Protein: Heterochromatin protein 1c (LD23881p) (Q9VCU6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Without children, isoform B
- Histone-lysine N-methyltransferase Su
- Histone H3
- Cleavage stimulation factor 64 kD subunit
- Chromo domain-containing protein rhino
- FI06908p
- Relative of woc, isoform C
- Histone H3.3A
Sequence:
MVKNEPNFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENCDCPNLIQKFEESRAKSKKRGEKKPKCEEIQKLRGYERGLELAEIVGATDVTGDIKYLVRWQFCDEFDLVPSAQIVEKDPQMLIDYFQKMAPYSRHIAMRMKGVPEELRLAASRTSYPHISSAPVEVPPEVDQSAELAGHLGGIAPQVDQAPQHHAPMDLANDTDDLASVSYSIPVPGVGDIAIDVPMAENQ
Protein: ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (Distal membrane arm assembly complex 2-like protein) (Mitochondrial ATP synthase regulatory component factor B) (Q9CRA7)
Organism: Mus musculus (Mouse)
Function: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:P22027}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:P22027}.
Interaction partners:
- ATP synthase peripheral stalk subunit b, mitochondrial
- ATP synthase peripheral stalk subunit d, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
Sequence:
MMMFGKISRQLCSLKKIPWSCDSRYFWEWLNTVFNKVDYERLRDVGPDRAASEWLLRCGAKVRYCGHQKWLHDYNTLPGSSIDRYKIQAIDATDSCIMDIGLDHMVGLEHVEKITLCKCHYIEDNCLQRLSQLENLRKSLLELEIIACGNVTDNGVIALRHFRNLKYLFLSDLPGVKDKEYLAQVFKTALPSLELKLNLK
Protein: Transcription factor TRY (Protein TRIPTYCHON) (Q8GV05)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Involved in epidermal cell fate specification. Negative regulator of trichome development, including endoreplication, by lateral inhibition involving intercellular interactions. Promotes the formation of hair developing cells (trichoblasts) in H position in root epidermis, probably by inhibiting non-hair cell (atrichoblasts) formation.
Subcellular location: Nucleus {ECO:0000269|PubMed:14561633}. Note=Detected in trichome nucleus.
Interaction partners:
- Transcription factor GLABRA 3
- Transcription factor EGL1
- Zinc finger protein GIS
- CRIB domain-containing protein RIC9
- Homeobox-leucine zipper protein GLABRA 2
- Zinc finger protein GIS2
- Probable F-box protein At2g36090
- CRIB domain-containing protein RIC6
- Zinc finger protein 8
- Protein TRANSPARENT TESTA GLABRA 1
Sequence:
MDNTDRRRRRKQHKIALHDSEEVSSIEWEFINMTEQEEDLIFRMYRLVGDRWDLIAGRVPGRQPEEIERYWIMRNSEGFADKRRQLHSSSHKHTKPHRPRFSIYPS
Protein: Uncharacterized protein (Q76NL5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFQLVSAAEVNKAYVSYPGGVSMCLRFPFCHCVWAHAMTLIEISGHYHIWVARGESEDWDYSNSFVVVCVVLLENIATNEREGKCHLTFHAATSMHKNYMLVALRGKAVKAKVSFRFKEV
Protein: Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C) (Q01098)
Organism: Mus musculus (Mouse)
Function: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex. Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning.
Subcellular location: Cell membrane {ECO:0000269|PubMed:1377365}; Multi-pass membrane protein {ECO:0000305}. Postsynaptic cell membrane; Multi-pass membrane protein.
Interaction partners:
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2A
- Glutamate receptor ionotropic, NMDA 2D
- Glutamate receptor ionotropic, NMDA 3B
- Glutamate receptor ionotropic, NMDA 2B
- Glutamate receptor ionotropic, NMDA 3A
- Disks large homolog 4
- Proenkephalin-B
- Neuronal acetylcholine receptor subunit alpha-7
- P2X purinoceptor 2
Sequence:
MGGALGPALLLTSLLGAWAGLGAGQGEQAVTVAVVFGSSGPLQAQARTRLTPQNFLDLPLEIQPLTIGVNNTNPSSILTQICGLLGAARVHGIVFEDNVDTEAVAQLLDFVSSQTHVPILSISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASYLSWRLLDVLTLELGPGGPRARTQRLLRQVDAPVLVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPPAAFPVGLISVVTESWRLSLRQKVRDGVAILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPGGYLVQPTMVVIALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDITPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWLSGICHNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPSSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTAGSAQANVLKMLQAARDMVSTADVSGSLDRATRTIENWGNNRRAPAPTTSGPRSCTPGPPGQPSPSGWRPPGGGRTPLARRAPQPPARPATCAGSPQPDVSRASCRHAWDARWPVRVGHQGSHLSASERRALPERSLLHAHCHYSSFPRAERSGRPFLPLFPEPPEPDDLPLLGPEQLARREALLRAAWARGPRPRHASLPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCRHVAQTQSLRLPSYREACVEGVPAGVAATWQPRQHVCLHTHTHLPFCWGTVCRHPPPCSSHSPWLIGTWEPPSHRGRTLGLGTGYRDSGVLEEVSREACGTQGFPRSCTWRRISSLESEV
Protein: Putative insulin-like growth factor 2-associated protein (Cell growth-inhibiting gene 44 protein) (Insulin-like growth factor II-associated protein) (P09565)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTPGVVHASPPQSQRVPRQAPCEWAIRNIGQKPKEPNCHNCGTHIGLRSKTLRGTPNYLPIRQDTHPPSVIFCLAGVGVPGGTCRPAPCVPRFAALPWATNHPGPGCLSDLRA
Protein: Mx1 protein (Myxovirus resistance 1) (Myxovirus resistance 2 isoform X1) (Q98990)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Ubl carboxyl-terminal hydrolase 18-like isoform X1
- Ubl carboxyl-terminal hydrolase 18-like isoform X1
- Cyclin-G-associated kinase
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- non-specific serine/threonine protein kinase
- RNA helicase
- Eukaryotic translation initiation factor 2-alpha kinase 3-like
- Intersectin-2-like
- UMP-CMP kinase 2, mitochondrial
Sequence:
MNNTLNQHYEEKVRPCIDLIDSLRSLGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRKKEGEEWHGKISYQDHEEEIEDPSDVEKKIREAQDEMAGVGVGISDDLISLEIGSPDVPDLTLIDLPGIARVAVKGQPENIGEQIKRLIRKFITKQETINLVVVPCNVDIATTEALKMAQEVDPEGERTLGILTKPDLVDKGTEETVVDIVHNEVIHLTKGYMIVKCRGQKEIMERVSLSEATEREKAFFKEHAHLSTLYDEGHATIPKLAEKLTLELVHHIEKSLPRLEEQIEAKLAETHAELERYGTGPPEDSAERMYFLIDKVTAFTHDAINLSTGEELKSGVRLNVFSTLRKEFGKWKLHLDHSGENFNQRIEGEVADYEKTYRGRELPGFINYKTFEVMVKDQIKQLEEPAVKKLKEISDAVRKVFLLLAQSSFIGFPNLLKSAKTKIEAIKQVNESTAESMLRTQFKMEMIVYTQDSTYSHSLSERKREEEDDRPLPTIKIRSTIFSTDNHATLQEMMLHLKSYYRISSQRLADQIPMVIRYLVLQEFASQLQREMLQTLQEKDNIEQLLKEDFDIGSKRAALQNKLKRLMKARSYLVEF
Protein: HEN-1 (HEsitatioN behavior) (G5ECA8)
Organism: Caenorhabditis elegans
Interaction partners:
- ALK tyrosine kinase receptor homolog scd-2
- Small RNA 2'-O-methyltransferase
Sequence:
MNSKVIFFVCALCSSVLSSQDGAFGHGNHRPLNDADALTAIKPVCETDRHGNKYIPCPIHDINDPRNWPCIKLADLCNGKADCPNGDDENYFQCFYHRARSEEYRRLMKMLEEIKGK
Protein: Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1) (P26323)
Organism: Mus musculus (Mouse)
Function: Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q01543}.
Interaction partners:
- F-box/WD repeat-containing protein 7
- Runt-related transcription factor 1
- Endothelial transcription factor GATA-2
- T-cell acute lymphocytic leukemia protein 1 homolog
- Transcription factor PU.1
- Transcriptional activator Myb
- RNA-binding protein EWS
- Tripeptidyl-peptidase 1
Sequence:
MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVRVNVKREYDHMNGSRESPVDCSVSKCNKLVGGGEANPMNYNSYMDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATSAYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLNVKEDPSYDSVRRGAWNNNMNSGLNKSPLLGGSQTMGKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTETSMYKYPSDISYMPSYHAHQQKVNFVPSHPSSMPVTSSSFFGAASQYWTSPTAGIYPNPSVPRHPNTHVPSHLGSYY
Protein: Collectrin (Transmembrane protein 27) (Q9ESG4)
Organism: Mus musculus (Mouse)
Function: Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity. May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane. Regulator of SNARE complex function. Stimulator of beta cell replication.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16330324, ECO:0000269|PubMed:17167413}; Single-pass type I membrane protein {ECO:0000255}. Note=Localizes to the brush border membranes of cells in the proximal tubules of kidney (PubMed:17167413). Colocalizes with SLC6A19 in the early proximal S1 tubule (PubMed:17167413). {ECO:0000269|PubMed:17167413}.
Interaction partners:
- Sodium-dependent neutral amino acid transporter B
- Sodium-dependent neutral amino acid transporter B
- Angiotensinogen
- Sodium- and chloride-dependent transporter XTRP3B
- Amino acid transporter heavy chain SLC3A1
Sequence:
MLWALFFLVTTIHAELCHPDAENAFKVRLSIRAALGDKAYVWDTDQEYLFRAMVAFSMRKVPNREATEISHVLLCNITQRVSFWFVVTDPSNNYTLPAAEVQSAIRKNRNRINSAFFLDDHTLEFLKIPSTLAPPMEPSVPVWIIVFGVIFCIVTVAIALLVLSGIRQRRRNNKGPPGVEDAEDKCENIITIENGIPCDPLDMKGGHINDGFLTEDERLTPL
Protein: dolichol kinase (EC 2.7.1.108) (Q38DD5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MMIYPRMRVEVSYSATLMVLWALLLTFMSWRVNQSSEGMAVLLLTIMSVATPDGESHLFLPLLFLAERLLGEVMSCRMLPHEFHASTILSFMTTSYSHTLWKRDSRPRIFMCGIRDVIVWLLLIFIAFKDCGVTVGGGVFVVFGFVFYVTLKRILGESEAILVGGLVGFYAFDAVSGWGFSSVGAFNADAPNKEGLHTVSVMTKAHIVSRTAIMCAVVMASVLYFASRFCLVAKFDNSKSSEQVMNVPRITFAFWMSLTIIVASAYAVGSMEIGEDIALWLVRYITASRFRILTIVYWSIAVPSMVVVVDVFTKDLSKVVRRKLFHFLAVAAFTPAAIADPQFLSLSLSVATSLSILLELGRYYGVSGASYVNAFVVHHIDSRDSIKGVVRTHIYLIYGLGLSMMLYYRRERNGKTEHHNSLLELSISVIPGLVSLGVVDACAGIVGSSFLLSYRRALGRYLSNNVYTERANATITHKTTTGTLGGFVCGVVFWVFVLFVSNVEQHGQAAMSLVLVVVCSVAECFTDGIDNLQLPLALYGAVTTLFAFSGWGEDSCA