wanglab/gogpt-training-data huggingface dataset:
Protein: Large ribosomal subunit protein uL16 (60S ribosomal protein L10) (L9) (Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein) (P41805)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Large ribosomal subunit protein eL14B
- Large ribosomal subunit protein eL8B
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL15
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein uL6B
- Large ribosomal subunit protein eL24B
- Small ribosomal subunit protein eS1A
- 60S ribosomal export protein NMD3
Sequence:
MARRPARCYRYQKNKPYPKSRYNRAVPDSKIRIYDLGKKKATVDEFPLCVHLVSNELEQLSSEALEAARICANKYMTTVSGRDAFHLRVRVHPFHVLRINKMLSCAGADRLQQGMRGAWGKPHGLAARVDIGQIIFSVRTKDSNKDVVVEGLRRARYKFPGQQKIILSKKWGFTNLDRPEYLKKREAGEVKDDGAFVKFLSKKGSLENNIREFPEYFAAQA
Protein: Progonadoliberin-1 (Progonadoliberin I) (Q6GVR1)
Organism: Meleagris gallopavo (Wild turkey)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MEKARKISVGVLLFTTSVAICLAQHWSYGLQPGGKRNVENLVESFQEIANEMENLGEAQKAECPGSYQHPSLSNLKETMASLIEGEARR
Protein: Colony stimulating factor 2 receptor subunit alpha (A0A8I6B5C9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MSIIPLPQLLALLCCCGLAAATQGPTDPSTPPNLGLAHFHNLTFDPGTWTLSWACGGHDGAVMSCTVIDQEAGIRRRVRSRGCRCRFQPMELHRGVDLEVAGDKGHAQVHQTLRFENEGAPGSGAENLTCEILAAHFLCCYWAVGPAAPDDIRYSLRVLNATGHEVASCSAAPGTPPTRCQADDLTHLPRLAYIVVTGQSRTGLVRFLDAVVNTKGIERLGPPDNVSASCNFSHCTITWAPPPTWAPMTEQDFRFEIEWKKAEPSSIAQKVVIAGREDNAFAFPSPAPRGRLWVRVRAGDTRSDRWSDWSPALELGSEATTPPRALVLAASSCAALLCALALGAACRR
Protein: F-box domain-containing protein (A0A1D8PDS4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Globin family profile domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MTILSTDVDLFSEAAKLPSEVITIIVDHLPKCILPELLHFPPIRREIASTILSDVYITENVQRHKGSDELLVGHSSCDCSHFKIKLIKLKQGITQWNIYPKTIHLERIEQFTNVSNNFPELLTEALSINGIFFGKEVLESNELTKFLENSNIKFDMIILNDFQDLVKIPPVATTISLFDTLLDNYNIPDVKKIDIEMKSRSMDSEFYDFPIDMDELQIKGEMLFQATLIPNLRKLCITAEY
Protein: Putative transferase YhbX (EC 2.-.-.-) (P42640)
Organism: Escherichia coli (strain K12)
Function: Probably does not transfer phosphoethanolamine to lipid A.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000305|PubMed:15919996}.
Interaction partners:
- Uncharacterized protein YjdJ
Sequence:
MTVFNKFARTFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFFVLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDPDEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQFAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVRDTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVPLSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETVYVRGFDELLLPHLSQALQQNTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDACYDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHVPMFIWYSPVLGDGVDRTTENNIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDSRVVDANHDVFDYVMLRKEFTEDKQGNPTPEGQG
Protein: Invertebrate-type lysozyme 3 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase) (O76357)
Organism: Caenorhabditis elegans
Function: Has bacteriolytic activity against Gram-positive bacteria. Plays a role in defense against bacterial pathogens. Involved in pharyngeal grinder function by enabling proper lysis of ingested bacteria.
Subcellular location: Late endosome lumen {ECO:0000269|PubMed:27525822}. Recycling endosome lumen {ECO:0000269|PubMed:27525822}. Lysosome lumen {ECO:0000269|PubMed:27525822}. Secreted {ECO:0000269|PubMed:27525822}. Note=Predominantly localizes to the recycling endosomal network in the basolateral region of intestinal cells. Secreted in the intestinal lumen only during dauer arrest stage, aging, or starvation. {ECO:0000269|PubMed:27525822}.
Interaction partners:
- VWFA domain-containing protein
- Lysozyme-like protein 7
- SCP domain-containing protein
- Zinc transporter Slc39a7
- Flavin-containing monooxygenase
- Lysozyme-like protein 3
- Peptidase C1A papain C-terminal domain-containing protein
- LYSozyme
- C-type lectin domain-containing protein
Sequence:
MFVKSLVFLTIAVAYASADCLHCICMRESGCKPIGCNMDVGSLSCGYYQIKLPYYEDCGQPTKKSGETTEAAWKRCANDLSCATTCVENYYNRYKSQCAGTGQGACEVMARNHNGGPQGCKHSGTLGYWNGIKSCCGCS
Protein: DASH complex subunit DAD1 (DUO1 and DAM1-interacting protein 1) (Outer kinetochore protein DAD1) (Q12248)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B. Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:25236177}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11782438, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:25236177}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:11782438, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:25236177}. Note=Associates with the mitotic spindle and the kinetochore. {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:25236177}.
Interaction partners:
- DASH complex subunit ASK1
- DASH complex subunit DUO1
- DASH complex subunit SPC34
- DASH complex subunit DAD2
- DASH complex subunit DAM1
- DASH complex subunit DAD3
- DASH complex subunit SPC19
- DASH complex subunit DAD4
- DASH complex subunit HSK3
- Inner kinetochore subunit CHL4
Sequence:
MMASTSNDEEKLISTTDKYFIEQRNIVLQEINETMNSILNGLNGLNISLESSIAVGREFQSVSDLWKTLYDGLESLSDEAPIDEQPTLSQSKTK
Protein: Rho guanine nucleotide exchange factor 39 (Q8N4T4)
Organism: Homo sapiens (Human)
Function: Promotes cell proliferation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22327280}.
Interaction partners:
Sequence:
MELSCPGSRCPVQEQRARWERKRACTARELLETERRYQEQLGLVATYFLGILKAKGTLRPPERQALFGSWELIYGASQELLPYLEGGCWGQGLEGFCRHLELYNQFAANSERSQTTLQEQLKKNKGFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLVVALAENTGPNSPDHQQLTRAARLISETAQRVHTIGQKQKNDQHLRRVQALLSGRQAKGLTSGRWFLRQGWLLVVPPHGEPRPRMFFLFTDVLLMAKPRPPLHLLRSGTFACKALYPMAQCHLSRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSRWYHSLTWAISSQKN
Protein: Lamin-B1 (P20700)
Organism: Homo sapiens (Human)
Function: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Subcellular location: Nucleus lamina {ECO:0000269|PubMed:28716252, ECO:0000269|PubMed:32910914}.
Interaction partners:
- Lamin-B2
- Delta
- Prelamin-A/C
- Emerin
- SUN domain-containing protein 1
- Lamina-associated polypeptide 2, isoform alpha
- Nesprin-2
- SUN domain-containing protein 2
- Nesprin-1
- Caspase-6
Sequence:
MATATPVPPRMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTPRASNRSCAIM
Protein: Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (3' terminal uridylyl transferase) (RNA editing 3' terminal uridylyltransferase 4) (RNA uridylyltransferase 4) (Q381M1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Terminal uridylyltransferase which, specifically, catalyzes the addition of Us to the 3'-hydroxyl group of single-stranded RNAs with a 3'-terminal U.
Interaction partners:
Sequence:
MPPSPAVVGRSLVNSFKQFVSKDLHTRHVDATYRLVLDCVAAVDPLMRLYTFGSTVVYGVHEKGSDVDFVVLNKTDVEDGKGGDAATQVAKGLQADILAKLARVIRQKHLSWNVEEVRRTRVPVVRVKGGGAVDFDITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNHLQFVPPSTIDVSRVEPLPPHLPLEEPADEGLELGTQVLDFLHFFLHEFDSDKQVISLNRPGITTKEELDWTKSAEDFARMNGEKVHYQWCIEDPYELNLNVGRNVTPLKRDFLRRHLEKARDTALLTIV
Protein: Kelch like family member 32 (Q5THT1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPSERCLSIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDITLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQVE
Protein: Ras-related protein Rab-5B (EC 3.6.5.2) (P61020)
Organism: Homo sapiens (Human)
Function: Protein transport. Probably involved in vesicular traffic.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17081065}; Lipid-anchor {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Early endosome membrane {ECO:0000269|PubMed:17081065}; Lipid-anchor {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Enriched in stage I melanosomes. {ECO:0000269|PubMed:17081065}.
Interaction partners:
- Ras-related protein Rab-5A
- Ras and Rab interactor 1
- Ras-related protein Rab-5C
- Early endosome antigen 1
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Ras and Rab interactor 2
- Ras and Rab interactor 3
- Leucine-rich repeat serine/threonine-protein kinase 2
- Rab GDP dissociation inhibitor alpha
- Rab5 GDP/GTP exchange factor
Sequence:
MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN
Protein: Slr1485 protein (P72606)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- Sll1033 protein
- ABC transporter
- Slr0924 protein
- Slr1493 protein
- Slr1484 protein
- Sll1204 protein
- Ferrichrome-iron receptor
- ABC transporter
- Slr1535 protein
- Sll1203 protein
Sequence:
MFKFAQIIFLAGSMVCLSSLGHQSLAGNLTLPDGSKCEGQISNGALNGQGTCQFTNGDRYEGQFVEGEKKGQGKYIFADGGYFEGVFEDDQMGSKGVRVYASQDRYEGEFVDGQPHGQGIYTTAAGLRYEGEFVDGQPTGKGTFIYTNGDRCSGTVVQGELNGSGKCEYNNGDQYEGTLKNGQPDGEGIFRFAAGGEYEGEFQSGEFSGQGTRIFANGNRFQGQFKQGLPSGQGQYNFADGASYQGEIRDGQPAGEGIYTFANGNRYQGQFVAGKFAGEGAFIFANGDRCQGQFSNNQLQGMATCDYVNGDTFEGIFEQGKKNGKGVYSFADGTRLEGVWKDDQYQERG
Protein: Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3) (Q6PHR2)
Organism: Homo sapiens (Human)
Function: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19279323, ECO:0000269|PubMed:19878745}. Note=Localizes to pre-autophagosomal structure during cellular senescence.
Interaction partners:
- Suppressor of fused homolog
- IST1 homolog
- Zinc finger protein GLI2
- Zinc finger protein GLI1
- Autophagy protein 5
- Transcriptional activator GLI3
- Ubiquitin-like-conjugating enzyme ATG3
- Ubiquitin-like protein ATG12
- Autophagy-related protein 13
- Phosphatidylinositol 3-kinase catalytic subunit type 3
Sequence:
MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMPSGESLGRATALVVQAVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEADTLDKEGLSESVRSSCTLQ
Protein: Plant intracellular Ras-group-related LRR protein 5 (Intracellular Ras-group-related LRR protein 5) (OsIRL5) (Q8S7M7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.
Interaction partners:
Sequence:
MASAAEAVEELTRLYRELPPRPAVEEVEAAEAVLASADAEEAARLDEVAREEASASASSSAAAPGRADGELLAVLREARRNAVRLRALQQRKEAAYVVELERRFKVFDDLIQRASRVVSSSSDAAEAGGGTTGDGYVGVGADSVDLEMELRKKEAAVAAAAAVAEMERGSKGLAALGLESKPISSLRRDVSAGTDMEKLSLIQVASLIESSAKKGITELSLRGKLVDQIEWLPVSLGKLQDVTELDLSENRIMALPSTIGSLRYLTKLDLHSNQLINLPDAFGELSNLIDLDLHANQLKSLPSSFGNLTSLANLDLSSNMLKALPDCLGKLANLRRLIVETNELEELPYTIGSCTSLVELRLDFNQLKALPEAIGKLEKLEILTLHYNRIKGLPTTVGSLSRLRELDVSFNEVEVIPENICFATSLVKLNLSRNFADLRALPKSIGNLEMLEELDISSNQIRVLPDSFRCLSRLRVFHADETPLEFPPREVVKLGAQAVVKYMNDLNAARGTNQKKTDRGSFWTWLFSLFGCCKKNQEVGLPV
Protein: Phenazine biosynthesis protein PhzB1 (O69753)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule. PhzB1 (operon phzA1B1C1E1F1G1) has a role in the biosynthesis of the phenazine during planktonic growth.
Interaction partners:
- Trans-2,3-dihydro-3-hydroxyanthranilate isomerase
- Probable pyridoxamine 5'-phosphate oxidase
- 5-methylphenazine-1-carboxylate 1-monooxygenase
- Phenazine-1-carboxylate N-methyltransferase
- anthranilate synthase
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- Phenazine biosynthesis protein PhzA1
- Phenazine biosynthesis protein PhzD1
- Protease LasA
- Elastase
Sequence:
MPDTTNPIGFTDANELREKNRATVEKYMNTKGQDRLRRHELFVEDGCGGLWTTDTGSPIVIRGKDKLAEHAVWSLKCFPDWEWYNINIFGTDDPNHFWVECDGHGKILFPGYPEGYYENHFLHSFELEDGKIKRNREFMNVFQQLRALSIPVPQIKREGIPT
Protein: Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104) (A1ZAJ2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for presynaptic maturation, has a role in axonal transport of dense-core vesicles carrying synaptic vesicle precursors, components required for the morphological transformation of axonal growth cones to mature boutons.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17643120}. Cell projection, axon {ECO:0000269|PubMed:30174114}. Note=Microtubule-associated. {ECO:0000269|PubMed:17643120}.
Interaction partners:
- Ras-related protein Rab-3
- Liprin-alpha, isoform E
- Kinesin light chain
- ADP-ribosylation factor-like protein 8
- Rab3 interacting molecule, isoform F
- FI18813p1
- Kinesin heavy chain 73, isoform E
- Kinesin heavy chain
Sequence:
MSSVKVAVRVRPFNSREIARESKCIIEMAGATTAITNPKVPPNTSDSVKRFNFDYSYWSHDHHDADFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEEQQEGIIPMICKDLFTRIQDTETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTDYQDIHDLIDEGNKARTVAATNMNETSSRSHAVFTIFFTQRRHDLMTNLTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVASKKKNTKKADFIPYRDSALTWLLRENLGGNSKTAMIAAISPADINYDETLSTLRYADRAKQIVCKAVVNEDANAKLIRELKEEIQKLRDLLKAEGIEVQEEDELTKSTVIKSPTKSRNRNGSTTEMAVDQLQASEKLIAELNETWEEKLKRTEEIRVQREAVFAEMGVAVKEDGITVGVFSPKKTPHLVNLNEDPNLSECLLYYIKEGLTRLGTHEANVPQDIQLSGSHILKEHCTFENKNSTVTLLPHKDAIIYVNGRKLVEPEVLKTGSRVILGKNHVFRFTNPEQARELRDKIETENEAENEVEKTDTQQVDWNFAQCELLEKQGIDLKAEMKKRLDNLEEQYKREKLQADQQFEEQRKTYEARIDALQKQVEEQSMTMSMYSSYSPEDFHQEEDVYTNPMYESCWTAREAGLAAWAFRKWRYHQFTSLRDDLWGNAIFLKEANAISVELKKKVQFQFTLLTDTLYSPLPPELASTVAPVHQEDEFGAPPVSKTLVAVEVTDTKNGATHHWSLEKLRQRLELMREMYHNEAEMSPTSPDYNVESLTGGDPFYDRFPWFRMVGRSFIYLSNLLYPVPLVHKVAIVNERGDVRGYLRIAVQPVLDEESIDFNNGVKQSARLVFNEDDAKPKYRALNEKDDVQRYIDNGGLDSKLEELEDVDSGRGIDSNSASECHENSEEPGEHLQVGKEFTFRVTVLQATGIGAEYADIFCQFNFLHRHEEAFSTEPVKNSASGAPLGFYHVQNITVPVTKSFIEYLKTQPIMFKIFGHYQTHPLHKDAKQDFVSRPPPRRMLPPSIPISQPVRSPKFGPLPCAPTSTVLAKHDVLVWFEICELAPNGEYVPSVVEHSDDLPCRGLFLLHQGIQRRIRITIVHEPTTEVKWKDINELVVGRIRNTPESSDEQDEDACVLSLGLFPGEALEVPGDDRSFYRFEAAWDSSLHNSALLNRVSQGGETIYITLSAYLELENCARPAIITKDLSMVIYGRDARTGPRSLKHLFSGQYRNPEANRLTGVYELALRRASEAGSPGVQRRQRRVLDTSSTYVRGEENLHGWRPRGDSLIFDHQWELEKLTRLEEVGRMRHLLLLRERLGMDTNPNPTTKTEKDVCNLAARAATSPVHMVIPQSPQTPVKDPQQIIPEREYNQREQDLMLKCLKLVQGRYTKSEANDTQTQSDVSPSDEGCADMTVSCISSNSMENNKFVIRRRLCSPDRADAPNGWEAPAPATQPALPLRLYVPELEEIRVSPVVARKGLLNVLEHGGSGWKKRWVIVRRPYVFIYRSEKDPVERAVLNLATAHVECSEDQAAMVKIPNTFSVVTKHRGYLLQTLGDKEVHDWLYAINPLLAGQIKSRLARRTLEPASQTASQIQATNAANANSASK
Protein: Protein SHI RELATED SEQUENCE 7 (Q9FXH7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering. Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning. Promotes style and stigma formation, and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM). Regulates anther dehiscence and floral development.
Subcellular location: Nucleus {ECO:0000269|PubMed:20706774}.
Interaction partners:
- Electron carrier/iron ion-binding protein
- Auxin canalization protein
- Probable indole-3-pyruvate monooxygenase YUCCA4
Sequence:
MAGLFYLGGRDHNKQDHHQEKDHNEDKSNNYLYLYKDEIYNNNKGFEIFPPQYFQQQQQQNHAAAPTNLYSFGMVPSGGNINNNRSTNRSLYFNVVSDHEPVRSSTGGFTVTRQGNMNCQDCGNQAKKDCPHMRCRTCCKSRGFDCQTHVKSTWVSAAKRRERQAQLAVLPAKRIRDANSRGGGDDDDDDKEDEKNDSCGGGSALACTRVVNASSSGLETSHLPPEISSPAVFRCMRVSSIDDEDEEYAYQTAVSIGGHVFKGILYDQGPSSDHHRYSSSLNGETSHQHHLNLMDSTPSAATTNAVTAVNTNNGSIDPSSLYTAVATPFNAFVAGGTPFFASSRC
Protein: Berberine bridge enzyme-like 1 (AtBBE-like 1) (EC 1.1.1.-) (Protein SIMILAR TO ELECTRON CAREER 1A) (AtSEC1A) (Q9LPC3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:18796151}.
Interaction partners:
- rhamnogalacturonan endolyase
- Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 2
- Defensin-like protein 313
- B3 domain-containing protein At5g60140
- At3g12470
- DUF674 family protein
- Transmembrane protein
- B3 domain-containing protein At5g60130
- Pectin lyase-like superfamily protein
- Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog
Sequence:
MKLSCLVFLIVSSLVSSSLATAPPNTSIYESFLQCFSNQTGAPPEKLCDVVLPQSSASFTPTLRAYIRNARFNTSTSPKPLLVIAARSECHVQATVLCTKSLNFQLKTRSGGHDYDGVSYISNRPFFVLDMSYLRNITVDMSDDGGSAWVGAGATLGEVYYNIWQSSKTHGTHGFPAGVCPTVGAGGHISGGGYGNMIRKYGLSVDYVTDAKIVDVNGRILDRKSMGEDLFWAIGGGGGASFGVILSFKIKLVPVPPRVTVFRVEKTLVENALDMVHKWQFVAPKTSPDLFMRLMLQPVTRNTTQTVRASVVALFLGKQSDLMSLLTKEFPELGLKPENCTEMTWIQSVMWWANNDNATVIKPEILLDRNPDSASFLKRKSDYVEKEISKDGLDFLCKKLMEAGKLGLVFNPYGGKMSEVATTATPFPHRKRLFKVQHSMNWKDPGTDVESSFMEKTRSFYSYMAPFVTKNPRHTYLNYRDLDIGINSHGPNSYREAEVYGRKYFGENFDRLVKVKTAVDPENFFRDEQSIPTLPTKPSSS
Protein: BPP (Baseplate protein) (Q9G096)
Organism: Lactococcus phage TP901-1
Subcellular location: Virion {ECO:0000256|ARBA:ARBA00004328}.
Interaction partners:
Sequence:
MASIKKVYRGMKNGAETINDDLEAINSELTSGGNVVHKTGDETIAGKKTFTGNVEVNGSLTLPTKSWSGELGGGIILSLRKKGTTVEYSIGGEISSSILANSNLVNRSVPNEFCPRNRCSLVGHMVGGWNAFHIDIPSSGVCQWFGPTASSGTPRGTGTYPID
Protein: Choline transporter-like protein 4 (Solute carrier family 44 member 4) (Thiamine pyrophosphate transporter 1) (hTPPT1) (Q53GD3)
Organism: Homo sapiens (Human)
Function: Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis.
Subcellular location: Membrane {ECO:0000269|PubMed:24379411, ECO:0000269|PubMed:26828122}; Multi-pass membrane protein {ECO:0000305|PubMed:24379411, ECO:0000305|PubMed:26828122}. Apical cell membrane {ECO:0000269|PubMed:24379411}.
Interaction partners:
- T-lymphocyte activation antigen CD80
- T-lymphocyte activation antigen CD86
Sequence:
MGGKQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGRCFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK
Protein: Protein TRACHEARY ELEMENT DIFFERENTIATION-RELATED 7 (Q9FI79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protein. Involved in the secondary cell wall (SCW) formation of vessel elements (e.g. protoxylem and metaxylem), thus promoting tracheary element (TE) differentiation.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:C1PGW1}; Single-pass membrane protein {ECO:0000255}. Secreted, cell wall {ECO:0000250|UniProtKB:C1PGW1}.
Interaction partners:
- Protein SIEVE ELEMENT OCCLUSION B
- Cysteine protease XCP2
- Cysteine protease XCP1
- EPIDERMAL PATTERNING FACTOR-like protein 1
Sequence:
MAASVEYFPYYSPPSHQHPLPSPVPPPPSHISPPPPPFSPPHHPPPPHFSPPHQPPPSPYPHPHPPPPSPYPHPHQPPPPPHVLPPPPPTPAPGHHVIIVVVISLGSLFFLAFLAAALFCYLKKRRKSSTKAEIIEFDEHLKVQETIVQGPHGEQTRVVMLEEDIHLVEDIHKTEKLSRPSHLSSTGRHAIDISDPNHHFTEQKS
Protein: GTP-binding nuclear protein (Q57WZ3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU363057}.
Interaction partners:
- Leucine-rich repeat protein
- Exportin-T
- Importin beta-1 subunit, putative
- Exportin 1
- Nuclear transport factor 2
- RanBD1 domain-containing protein
- Ran-binding protein 1, putative
- Importin-alpha re-exporter protein, putative
- Ran-binding protein, putative
- Elongation factor 1-alpha 1
Sequence:
MQASSTADCVATFKLVLVGDGGTGKTTFVKRHLTGEFEKRYVATVGVDVHPLTFHTNRGKICFNCWDTAGQEKFGGLRDGYYIEGQCAIIMFDVTSRNTYKNVPNWHRDITRVCDNIPIVLVGNKVDCAERQVKAKMITFHRKKGLQYYDISAKSNYNFEKPFLWLAKKLANDPNLTLVEAPMLDPNVQPLTAEQLQALQEEARAVENVVLPMGEDD