wanglab/gogpt-training-data huggingface dataset:
Protein: Large ribosomal subunit protein uL15m (54S ribosomal protein L10, mitochondrial) (YmL10/YmL18) (P36520)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein uL16m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL23m
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein uL5m
- Large ribosomal subunit protein mL49
- Large ribosomal subunit protein uL13m
Sequence:
MKAERQTGLRNSFTTVIGRKLINTFVPSMMLTSVAGNDIFFRGLFKSPVLAFQSYRYVSILGQLKPSDGSTKSFKRLGRGPSSGLGKTSGRGQKGQKARGKVKSWFEGGQTPIYKLFPKIGFTNVGAKPLKELNLKRIQWFHDKNRLHLQPGEVLDMNKMRKLGLVTGPIKYGVKILASGKFHYNLPIALEASRASAKAIAAIEKAGGKFTARYYTPLGLRAHLNPQWFLEKRGRVPLQARPTKRRDIDFYSKEEKRGYLVMEKDKLLQDIKEAQNKGSRHFLKQNVKKSSLEIELEELSPEKDWVPVVSNSKVMNIKALDH
Protein: Putative protein CLUHP3 (Clustered mitochondria (cluA/CLU1) homolog pseudogene 3) (KIAA0664-like protein 3) (Q96NS8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFLNGNCLETLKKKEPEGGRRRLSHPGNMGWMRPSQETTPPDRSHHSGFGLFCGDPGPEIEPFSLWVFPQEMVLEIHQLFMDHEYPCHHITSHCTWVAAHWTTSQSCAAWQGCRRACCSTWWKSPAQCTRPTVMSATFETAQEPGPS
Protein: Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl coenzyme A thioester hydrolase) (MTE-I) (Very-long-chain acyl-CoA thioesterase) (Q9QYR9)
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:25114170}.
Interaction partners:
- Cytosolic acyl coenzyme A thioester hydrolase
- Acyl-coenzyme A thioesterase 1
- Acyl-coenzyme A thioesterase THEM5
- Peroxisomal succinyl-coenzyme A thioesterase
- Acyl-coenzyme A thioesterase THEM4
- Acyl-coenzyme A thioesterase 3
- Acyl-coenzyme A thioesterase 5
- Very-long-chain enoyl-CoA reductase
- Fructose-1,6-bisphosphatase 1
- Fructose-1,6-bisphosphatase isozyme 2
Sequence:
MVASSFAVLRASRLCQQDWKSWARLFVPPPLSTGGRTTWARTNATLSVEPEGRSCWDEPLSIAVRGLAPEQPVTLRSALRDEKGALFRAHARYRADAGGELNLARAPALGGSFSGLEPMGLLWAMEPERPLWRLIKRDVQTPFLVELEVLDGHEPDGGQRLAQAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKSIETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPVSLLRNQVKMTKDGLLDVVEALQSPLVDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPRAHAVAQVDAWQQLQTFFHKQLGSKS
Protein: 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase (6-OCH-CoA hydrolase) (EC 3.7.1.21) (6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase) (Q39TV7)
Organism: Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15)
Function: Involved in the central benzoyl-CoA catabolism. Catalyzes the addition of one molecule of water to the double bond and the hydrolytic cleavage of C-C bond in the alicyclic ring, 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA) to yield 3-hydroxypimelyl-CoA.
Interaction partners:
- 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
- Enoyl-CoA hydratase/isomerase
- 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase
- Cyclohexa-1,5-dienecarbonyl-CoA hydratase
- Benzoyl-CoA reductase, putative
- Iron-sulfur cluster-binding oxidoreductase, putative benzoyl-CoA reductase electron transfer protein
- Thiolase
- Benzoylsuccinyl-CoA thiolase subunit BbsB
- acetyl-CoA C-acyltransferase
- Thiolase
Sequence:
MARTDEIIARTAPGHLNDHNLIDREVESLCDGMVKYEKRPAKRHDGSVAEGIYNAWIILDNPKQYNSYTTDMVKAIILAFRRASVDRSVNAVVFTGVGDKAFCTGGNTKEYAEYYAGNPQEYRQYMRLFNDMVSAILGCDKAVISRVNGMRIGGGQEIGMACDFSIAQDLANFGQAGPKHGSAAIGGATDFLPLMVGCEQAMVSGTLCEPFSAHKAARLGIICDVVPALKVGGKFVANPTVVTDRYLDEYGRVVHGEFKAGAAFKEGQGQIKEGEIDLSLLDEKVESLCTKLLETFPECMTKSLEELRKPKLHAWNLNKENSRAWLALNMMNEARTGFRAFNEGTKETGREIDFVKLRQGLAKGTPWTEELIESLMPTAQK
Protein: Bacterial microcompartment shell protein PduB (Bacterial microcompartment protein homotrimer) (BMC-T) (Propanediol utilization protein PduB) (P37449)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: The two proteins produced are among the major shell proteins of the bacterial microcompartment (BMC) dedicated to 1,2-propanediol (1,2-PD) degradation. Required for structural integrity of BMCs and to mitigate propionaldehyde toxicity. The N-terminal 13 residues are important for correct assembly of the BMC shell. The isolated BMC shell component protein ratio for J:A:B':B:K:T:U is approximately 15:10:7:6:1:1:2. The N-terminus of the long form (PduB) is required for correct formation of BMCs, deletions in the first 37 residues have substantially reduced levels of the major lumen enzymes. May play a major role in binding the enzyme contents to the shell.
Subcellular location: Bacterial microcompartment {ECO:0000269|PubMed:12923081, ECO:0000269|PubMed:27063436}.
Interaction partners:
- Propanediol dehydratase medium subunit
- Propanediol dehydratase large subunit
- Bacterial microcompartment shell protein PduK
- Propanediol dehydratase-reactivating factor large subunit
- Propanediol dehydratase small subunit
- Bacterial microcompartment shell vertex protein PduN
- Bacterial microcompartment shell protein PduU
- Bacterial microcompartment shell protein PduJ
- Bacterial microcompartment shell protein PduA
- Propanediol dehydratase-reactivating factor small subunit
Sequence:
MSSNELVEQIMAQVIARVATPEQQAIPGQPQPIRETAMAEKSCSLTEFVGTAIGDTLGLVIANVDTALLDAMKLEKRYRSIGILGARTGAGPHIMAADEAVKATNTEVVSIELPRDTKGGAGHGSLIILGGNDVSDVKRGIEVALKELDRTFGDVYGNEAGHIELQYTARASYALEKAFGAPIGRACGIIVGAPASVGVLMADTALKSANVEVVAYSSPAHGTSFSNEAILVISGDSGAVRQAVTSAREIGKTVLATLGSEPKNDRPSYI
Protein: Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L) (P37172)
Organism: Mus musculus (Mouse)
Function: Bone morphogenetic protein (BMP) type I receptor that is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. As a type I receptor, forms heterotetrameric receptor complexes with the type II receptors AMHR2, ACVR2A ors ACVR2B. Upon binding of ligands such as BMP7 or BMP9 to the heteromeric complexes, type II receptors transphosphorylate ACVR1 intracellular domain. In turn, ACVR1 kinase domain is activated and subsequently phosphorylates SMAD1/5/8 proteins that transduce the signal. In addition to its role in mediating BMP pathway-specific signaling, suppresses TGFbeta/activin pathway signaling by interfering with the binding of activin to its type II receptor. Besides canonical SMAD signaling, can activate non-canonical pathways such as p38 mitogen-activated protein kinases/MAPKs (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Bone morphogenetic protein 7
- Bone morphogenetic protein 6
- Bone morphogenetic protein receptor type-2
- Bone morphogenetic protein receptor type-1A
- Bone morphogenetic protein receptor type-1B
- Bone morphogenetic protein 4
- Activin receptor type-2A
- Activin receptor type-2B
- Peptidyl-prolyl cis-trans isomerase FKBP1A
- Mothers against decapentaplegic homolog 1
Sequence:
MVDGVMILPVLMMMAFPSPSVEDEKPKVNQKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACILGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTLAELLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC
Protein: Melanopsin opn4x2 (Opsin 4xb) (G8Z413)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}.
Interaction partners:
Sequence:
MEPQRQIYKRLDVPDHVHYIIAFLILIIGTLGVSGNALVMFAFYSNKKLRSLPNYFIMNLAVSDFLMAITQSPIFFINCLYKEWMFGELGCKIYAFCGALFGITSMINLLAISIDRYLVITKPLQTIQWNSKRRTGLAILCIWLYSLAWSLAPLIGWSSYIPEGLMTSCTWDYVSPSPANKSYTMMLCCFVFFIPLSIILYCYLFMFLSVRQASRDLEMLSSQKSSFVKQQSMRSEWKLAKIAAVVIVVYVLSWAPYACVTLVAWAGHQDVLTPYSKTLPAVLAKSSAIYNPFIYAIIHNKYRATLAERVPGLSCLSRSQKDGLSSSTNSDASAQDSSVSRQSSVSKNRLHSTMVKGEVELDLMENRPKLSFKGFSRRRLLKCSSLLIEKPPVQMKESLSLCERDLVSGSFSIAAAPMVMSSKQKSRSADLIHSSGDSQNPMQKLLSISQLQQIHEGEAS
Protein: Protein RALF-like 19 (Q6NME6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Protein RALF-like 11
- At5g42680
- Protein RALF-like 10
- Protein RALF-like 15
- Pollen-specific leucine-rich repeat extensin-like protein 4
- Probable receptor-like protein kinase At2g21480
- GPI-anchored protein LLG3
- GPI-anchored protein LLG2
- ABC transporter B family member 13
- Protein RALF-like 8
Sequence:
MGIKILLILGLLTLAVVAESANATWTLTKSCVNGQGCIGEDGELDYLMDSETNRRQLAARRSYISYGALRKNNVPCSRRGRSYYDCKKRKRANPYRRGCSVITHCYRQTS
Protein: F-box protein PP2-B10 (Protein PHLOEM PROTEIN 2-LIKE B10) (AtPP2-B10) (Q9ZVQ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Interaction partners:
- Protein PHLOEM PROTEIN 2-LIKE A9
- F-box protein At4g05010
- COBRA-like protein 7
Sequence:
MGRKRRVKSESSPFDSFPEDCISYIISFTNPRDACVAATVSKTFESTVKSDIIWEKFLPADYESLIPPSRVFSSKKELYFSLCNDPVLFDDDKKSVWLEKASGKRCLMLSAMNLSIIWGDNPQYWQWIPIPESRFEKVAKLRDVCWFEIRGRTNTRVLSPRTRYSAYIVFKGVDKCYGFQNVAIEAAVGVVGQEPSRRLICFSEAIRRGRRNVVKPKQREDGWMEIELGEFFNDGGIMDNDEIEMSALETKQLNRKCGLIIQGIEIRPAKIL
Protein: cDNA: FLJ22395 fis, clone HRC07889 (Q9H6C4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000256|ARBA:ARBA00004132}. Late endosome membrane {ECO:0000256|ARBA:ARBA00004492}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004492}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004492}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004630}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004630}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004630}.
Interaction partners:
Sequence:
MQAARGSLANHTSIAELIKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPGENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF
Protein: Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8) (O44502)
Organism: Caenorhabditis elegans
Function: Required for normal Golgi function.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 2
- Immediate early response 3-interacting protein 1
- Gelsolin-like protein 1
- t-SNARE coiled-coil homology domain-containing protein
- Putative syntaxin-5
Sequence:
MDSDYIFHNGDDIRNMGLEEMRRQKVLLASELKAIDAQISDLAFNNYGTYADAGRATHDCSKTFGEMRDKTVNLSDQAEELTSAFVEFRAKAKQLSEEQDLVRKALDKSNPIWELLTLPSRMDICIRAGYYDLAYTLTNYGLQLQQQTQLYRNPLIKKVADHLVEARAYLLEELFNKFAGPLDLAESIKVVNNVRKMPSLTANQLRIAVLQHRDIYLEKQILDISGNVDMIVQAIEIYRTSMYDTLVLYLAVFPENEVVRKNPNADPRWESWPVLPPNSILSQWVISNVKKMLDLITKADVKSAVDLSAVWTKLMAMASSFGRMGIDFRPLIAGKLTKLIEQRFRQNVQEATSRLTGSSRDIVMIGIDPASLPQFETAPDSPPVAAAELSLWDDMTIYTNSVVDALNGLRFILTPVVLSTVVVSLRDSIRSILTWLASSHSNSANFSRAVRIVCTSVAPFFEKCVAFFFPPATVSKIFGSSISKRQYLQFIELDMKQLAASCDGAEKIEEIVKPLLQKRTLEEIGLENVLKPTKPEEEKTKFFLEETVEDGPGLAEPQEEASESVKEQETTSELEKKHGTDFETAETQEMVSEPVKEHETTSELTKEQEPAFEPEKLHETPPEPMEPQNFGESEAKAAHNPEAHLELGETSENQEIREQEHKEVVITSTEPEFHEIDLNSAVLIPKIAVEPQLDPISEYLTELTQDDPIEEEEGWGWGDDDGEEQEISSKEVESPKEKCKKDD
Protein: Sterol carrier protein 2 (EC 2.3.1.155) (EC 2.3.1.16) (EC 2.3.1.176) (Acetyl-CoA C-myristoyltransferase) (Non-specific lipid-transfer protein) (Propanoyl-CoA C-acyltransferase) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (SCP-chi) (Sterol carrier protein X) (A0A384NY87)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
Interaction partners:
Sequence:
MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQACVGYVFGDSTCGQRAIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQLQPGNAKL
Protein: Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt)) (P46199)
Organism: Homo sapiens (Human)
Function: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Subcellular location: Mitochondrion.
Interaction partners:
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS10m
- Large ribosomal subunit protein bL9m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS12m
- Translation initiation factor IF-3, mitochondrial
- Large ribosomal subunit protein uL2m
Sequence:
MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTGAALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNTDIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIYRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAKTSWDPGF
Protein: Uncharacterized protein C2orf72 homolog (Q9CYS6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MESELEALAPRPASPAEPPFQALVEAAGGRGQVLLVGELWEREQSRALLRDFAGAVFPPESAPGKPGCAEAESAGTAAATESHGAPGAKAERAIRSPLVFVLCRVGSLTSRESRRRLREMLRDVRDRRCEGAALVGVLVADTGADDARAPELQLLETLLRTVFGRQVGGPVQAAAFRPGCPASSLAVQEAACRALQAAGPGRPEGAWERPARTGLLTCFSWGPRRQRKNRGVTSSQGPAQEHLQFSEEELALTPVFPNGDCEDRGNGSRAQDGGVHIPPDPPEDTR
Protein: Cytochrome b6-f complex subunit 6 (Cytochrome b6-f complex subunit PetL) (Cytochrome b6-f complex subunit VI) (Q6ENF5)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00433}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00433}.
Interaction partners:
Sequence:
MLTITSYFGFLLAALTLTLALFIGLNKIRLI
Protein: Serpin family F member 1 (A0A8I6GIT3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQTLVLLLWTGALLGHGSSQNVPDSSQDSPAPDSTGEPVVEEDDPFFKAPVNKLAAAVSNFGYDLYRLRSGAVSTGNILLSPLSVATALSALSLGAEQRTESVIHRALYYDLINNPDIHSTYKELLASVTAPEKNFKSASRIVFERSY
Protein: Probable enoyl-CoA hydratase 1, peroxisomal (EC 4.2.1.17) (Enoyl-CoA hydratase isoform A) (Q6NL24)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.
Subcellular location: Peroxisome {ECO:0000305|PubMed:17951448}.
Interaction partners:
- Peroxisomal acyl-coenzyme A oxidase 1
- Putative peroxisomal acyl-coenzyme A oxidase 1.2
- Acyl-coenzyme A oxidase 4, peroxisomal
- Peroxisomal fatty acid beta-oxidation multifunctional protein AIM1
- Acyl-coenzyme A oxidase 2, peroxisomal
- Probable acyl-CoA dehydrogenase IBR3
- Acyl-coenzyme A oxidase 3, peroxisomal
- Putative acyl-coenzyme A oxidase 3.2, peroxisomal
- Putative acyl-coenzyme A oxidase At3g06690
- 3-hydroxyacyl-CoA dehydrogenase family protein
Sequence:
MDQTVSENLIQVKKESGGIAVITINRPKSLNSLTRAMMVDLAKAFKDMDSDESVQVVIFTGSGRSFCSGVDLTAAESVFKGDVKDPETDPVVQMERLRKPIIGAINGFAITAGFELALACDILVASRGAKFMDTHARFGIFPSWGLSQKLSRIIGANKAREVSLTSMPLTADVAGKLGFVNHVVEEGEALKKAREIAEAIIKNEQGMVLRIKSVINDGLKLDLGHALTLEKERAHAYYSGMTKEQFRKMQEFIAGRGSKKPSSKL
Protein: UDP-glucuronosyltransferase (EC 2.4.1.17) (D3XD60)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}. Membrane {ECO:0000256|RuleBase:RU362059}; Single-pass membrane protein {ECO:0000256|RuleBase:RU362059}.
Interaction partners:
Sequence:
MLKKGWLWGLGSGLLLLWLSAGLRPVQGGRVLVMPVEGSHWLSMKVLATELARRGHDVLVLVPEKNILIQSSELFRTETFPVKISKEQLSKSLKGFQQGVFTRSPALMDVFVQLERLLNFTGSQVEGCESLLYNEPLMRKLKEQNFELMLTDPFLPCGPIIATALGVPAVYFLRGMPCGIDLLASQCPSPPSYVPRFHSGTSDKMNFVERIRNFFMSGFELVLCKVMYASFDELAARYLKKDVTYKEIIGRGALWLHRYDFTFEYPRPIMPNMVFIGGINCQKSAEISAEVEEFVNGSGEHGIVVFSLGSLVSSMPKEKADIFFKAFSMIPQRVLWRYTGEIPDNVPENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICRGVPMVMLPLFGDQADNVHRVATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHELNWLQYHSLDVIGFMLLIVLIVTLAMLKCCSLCWRRCCRKTQKRKED
Protein: Glucan endo-1,3-beta-glucosidase 13 (EC 3.2.1.39) ((1->3)-beta-glucan endohydrolase 13) ((1->3)-beta-glucanase 13) (Beta-1,3-endoglucanase 13) (Beta-1,3-glucanase 13) (Q9FJU9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted, cell wall {ECO:0000305}. Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Interaction partners:
- Probable LRR receptor-like serine/threonine-protein kinase At3g47570
- 2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomal
- Protein NRT1/ PTR FAMILY 5.10
Sequence:
MARDFKLIFSISILLLLLDCCYGGKVGVCYGRSADDLPTPSKVVQLIQQHNIKYVRIYDYNSQVLKAFGNTSIELMIGVPNSDLNAFSQSQSNVDTWLKNSVLPYYPTTKITYITVGAESTDDPHINASSFVVPAMQNVLTALRKVGLSRRIKVSTTLSLGILSRSFPPSAGAFNSSYAYFLRPMLEFLAENKSPFMIDLYPYYAYRDSPNNVSLDYVLFESSSEVIDPNTGLLYKNMFDAQVDALYYALTALNFRTIKIMVTETGWPTKGSPKEKAAASSDNAETYNSNIIRHVVTNQGTPAKPGEAMNVYIFSLFNENRKAGLDSERNWGLFYPDQTSVYQLDFTGKSNGFHSNSSGTNSSGSSNSWCIASSKASERDLKGALDWACGPGNVDCTAIQPSQPCFQPDTLVSHASFVFNSYFQQNRATDVACSFGGAGVKVNKDPSYDKCIYITAGGNKTKATNATALTSSASTPRGNELLQWILKLCLMISLFFSLQTMNSQAL
Protein: Cytochrome c oxidase subunit 7A1, mitochondrial (Cytochrome c oxidase subunit VIIIc) (VIIIC) (Cytochrome c oxidase subunit VIIa-heart) (Cytochrome c oxidase subunit VIIa-H) (Cytochrome c oxidase subunit VIIa-muscle) (Cytochrome c oxidase subunit VIIa-M) (P07470)
Organism: Bos taurus (Bovine)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:27605664, ECO:0000269|PubMed:31533957}; Single-pass membrane protein {ECO:0000269|PubMed:27605664, ECO:0000269|PubMed:31533957}.
Interaction partners:
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
- Cytochrome b-c1 complex subunit 10
- Cytochrome b-c1 complex subunit 9
- Cytochrome c oxidase subunit 6B1
- Cytochrome c oxidase subunit 6A2, mitochondrial
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 5B, mitochondrial
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome b
- Cytochrome c oxidase subunit 7C, mitochondrial
Sequence:
MRALRVSQALVRSFSSTARNRFENRVAEKQKLFQEDNGLPVHLKGGATDNILYRVTMTLCLGGTLYSLYCLGWASFPHKK