wanglab/gogpt-training-data huggingface dataset:
Protein: Cellular retinoic acid binding protein type II (Cellular retinoic acid-binding protein 2, a) (Cellular retinoic acid-binding protein 2a) (Crabp2a protein) (Q801Y4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Cytochrome P450 26A1
- Retinoic acid receptor alpha-A
- Retinoic acid receptor gamma-A
- Arginyl-tRNA synthetase
- Retinol dehydrogenase 1
- Tuftelin 1a
- Retinoic acid receptor alpha-B
Sequence:
MDRKIPDFAGTWKMKSSENFEELLKALGVNVMLRKIAVAAASKPSVEITQEGETLTIKTSTSVRTTNVTFTVGQEFNEATVDGRPCTSFPRWVTDSKISCEQTLQKGEGPKTSWTREITNDAELILTMTADDVVCTRVYVRE
Protein: Possible PhiRv2 prophage protein (P71947)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Virion {ECO:0000256|ARBA:ARBA00004328}.
Interaction partners:
- Possible PhiRv2 prophage protease
- Probable PhiRv1 phage protein
- Oxaloacetate decarboxylase
- Probable conserved transmembrane protein
- Putative prophage phiRv2 integrase
- Probable PhiRv1 phage protein
- Putative acetolactate synthase large subunit IlvB2
- Uncharacterized protein Rv2645
- Probable PhiRv1 phage protein
- Putative thiosulfate sulfurtransferase SseB
Sequence:
MTNEQHFADDGDIKQLSLDETRSAAKQLLDSVEGDLTGDVAQRFQALTRHAEELRAEQRRRGREAEEALRRCRAGELRVVPGAPTGGDDGDAPPGNSLRDIAFRTLDVCVRDGLMSSRAAEAAETLCRTGPPQSTSWAQRWLAATGNRDYLGAFVKRVSNPVAGHTTWTDREAAAWREAAAVAAEQRAMGLVDTAGGFLIPAALDPAILLSGDGSTNPIRQVARVVQTTSEVWRGVTSEGAEAHWYSEAQEVSDDSPTLAQPAVPSYRGSCWIPFSLEIEGDAAGFVAEVGRVLADSVEQLQAAAFVSGSGNGEPTGFVSALTGTADYTVTGAGTEAVVAADVYALQSALPPRFQSNSAFAANLSTINVLRQAETANGALKFPSLHASPPMLAGKHIWEVSNMDTVDAAVTATNYPLVLGDWKQFIITDRVGSTVELVPHVFGGNRRPTGQRGFFCWFRVGSDVLVDNAFRVLKVQTTA
Protein: Sister chromatid cohesion protein pds5 (Precocious dissociation of sisters protein 5) (Q9HFF5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the establishment and maintenance of sister chromatid cohesion during S phase. Prevents their formation until eso1 is present. May also have a role during meiosis.
Subcellular location: Nucleus. Chromosome, centromere. Note=Localized to chromatin throughout the cell cycle.
Interaction partners:
- Cohesin subunit rad21
- Structural maintenance of chromosomes protein 3
- Structural maintenance of chromosomes protein 1
- Sister chromatid cohesion protein mis4
- Cohesin subunit psc3
- Wings apart-like protein homolog 1
- Meiotic recombination protein rec8
- Meiotic recombination protein rec11
- Separin
- N-acetyltransferase eso1
Sequence:
MIKLQFQRNIVPTHDNPLTTSEILKRLRDLLGELTSLSQDTIDRDSVLPVARSLVNNNLLHHKDKGIRSYTLCCIVELLRLCAPDAPFTLSQLEDIFQVILKILSGLMNQESTYYPQIYEILESLSNVKSAVLIVDLPNAEEFLVNIFRLFFDLARKGTTKNVEFYMLDIINQLINEINTIPAAALNILFAQLISGKGVRQTIGSSDSTNHGPAFQLARNIFHDSADRLQRYVCQYFSDIIFDSRDSLSDSMTTPEFIFSHNLVLQLWKYAPTTLLNIIPQFENELQAEQTSVRLVAIETVGLMLQDNAIWSDYPRVWSAFCGRLNDKSVACRIKCIEVASNALQNSLATSEIIENVVQMLQSKLADTDEKVRVATLKTIEQLTFETFKMQFSVQALKLMGDRLRDRKLNVRLQAIRTLSQIYNRAYQDLIDGVEYSIQMFSWIPSSLLEVFYVNDETTNAAVEICMAELVLQYLSSDTQTRLNRLFLSIKYFSEKAMRVFILLLQRQVKYSELLNYYIECCKNYNGGVMDNDEESITNKLKKVIDIISSKSSNPTLTEATFRKFAELNDRQSYKMLLQTFSIKSEYQVVLKSIKYLFKRVSETLSTASLECFRIFVYRSALFAFNKSNVHEIIQLLNEPVKYHNFLKPSEALLQHLPLIHPNIYGEVVIEVENIIVSSGIESDPKVIKALSQFSKRKKNFSIQTTTAEILRKLCLHGTQEQAKQAATIIAITETKEFKLDMITNIVENLEYNGGLPVRLMTLGQLFLYTLEEVEKVADQVTEFLVKKVIQRFPEKYDDTHNDEEWCTYEKLDNLTMCKVLAIRVLVNRLRAAAGGTEALNIGAPIIKLLKVLLMADGELSPFKNTPKISRAYLRLTASKYFLKLCSIPFYAEHIDFSSYVQISLLCQDENFDVRNLFLTKLQKQLQLKKLPISYYPLLFLTAVDPEEEIKTKASIWIRSQVAFFQKTHDFTMEYVATYLIHLLSHHPDISSIESENSLDFIAYIRFYVDTVVNSENVPIVFHLMQRIKQSYDVIEDGNNYIYVLSDMAQKILQVKSQNFGWSLTTYPKQIKLPYEILRPIPSIDEKKRIFNKIFITPKMESQIEHAIRTPVSSFAKQTTNKHANLKQKKTHSSKSDKKSSRRRKNEKRRKLNEQNPNIRNVPERSSSRFQGIRINYSEAPSSSEEISEEEEEISEEDFDEIEDL
Protein: Testis-specific Y-encoded protein 2 (Testis-specific Y-encoded protein Q1) (A6NKD2)
Organism: Homo sapiens (Human)
Function: May be involved in sperm differentiation and proliferation.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q01534}. Nucleus {ECO:0000250|UniProtKB:Q01534}.
Interaction partners:
Sequence:
MRPEGSLTYRVPERLRQGSCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS
Protein: C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367) (Q9UMR7)
Organism: Homo sapiens (Human)
Function: C-type lectin receptor that binds carbohydrates mannose and fucose but also weakly interacts with N-acetylglucosamine (GlcNAc) in a Ca(2+)-dependent manner. Involved in regulating immune reactivity. Once triggered by antigen, it is internalized by clathrin-dependent endocytosis and delivers its antigenic cargo into the antigen presentation pathway resulting in cross-priming of CD8(+) T cells. This cross-presentation and cross-priming are enhanced by TLR7 and TLR8 agonists with increased expansion of the CD8(+) T cells, high production of IFNG and TNF with reduced levels of IL4, IL5 and IL13. In plasmacytoid dendritic cells, inhibits TLR9-mediated IFNA and TNF production. May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18258799}; Single-pass type II membrane protein {ECO:0000305}; Extracellular side {ECO:0000269|PubMed:18258799}.
Interaction partners:
- Lymphocyte antigen 75
- Tyrosine-protein phosphatase non-receptor type 11
- Toll-like receptor 8
- Toll-like receptor 2
Sequence:
MTSEITYAEVRFKNEFKSSGINTASSAASKERTAPHKSNTGFPKLLCASLLIFFLLLAISFFIAFVIFFQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL
Protein: Putative receptor-like protein kinase At5g39000 (EC 2.7.11.-) (Q9FID8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Receptor-like protein 45
- Receptor-like protein 14
- Thioredoxin superfamily protein
- Probable disease resistance protein At4g19530
- Disease resistance protein RPS4B
- GPI-anchored protein LLG3
- Cyclase-associated protein 1
- Receptor like protein 21
Sequence:
MIRHALLIFSILVSTPIVGEGATSTYEPTDVFLFNCGDTSNNVDVSGRNWTAENQKILSSNLVNASFTAQASYQESGVSQIPYMTARIFRSEFTYSFPVTPGSNFLRLYFYPTRYGSQFNAVKSFFSVKVNGFTLLNNFSADLTVKASKPQTEFIIKEFIIPVYQTLNLTFTPSLDSLAFVNGIEIVSIPNRFYSKGGFDDVITNVGSSVDFHIENSTAFETVYRLNVGGKTVGDSGMFRRWVSDDEIILSESSGISPIVPDIKINYTEKTPSYVAPDDVYATSRSMGNADHPEQNLNFNLTWLFTVDAGFSYLVRLHFCETLSEVNKEGQRVFSIFIENQTATLEMDVFRMSGGSWIPMYLDYTVIAGSGSGRRHDLRLDLHPLVSINPKYYDAILNGVEILKMNDPDGNLAGPNPDPLVSPDLIPNRATPRIRKNKSHILPITLAVVGSLVVLAMFVVGVLVIMKKKKKSKPSTNSSWCPLPHGTDSTNTKPAKSLPADLCRRFSIFEIKSATNDFEDKLIIGVGGFGSVYKGQIDGGATLVAVKRLEITSNQGAKEFETELEMLSKLRHVHLVSLIGYCDEDNEMVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEICIGAARGLQYLHTGAKYTIIHRDIKTTNILLDENFVTKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYRRQVLTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNYRRGTVDQIIDSDLSADITSTSLEKFCEIAVRCVQDRGMERPPMNDVVWALEFALQLHETAKKKNDNVESLDLMPSGEVGTTTDGEDDLFSRTTGHVGKSTTTDDSVLVVGDERSGSSWGVFSEINEPKAR
Protein: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (A2QZ43)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Interaction partners:
Sequence:
MSSKSRLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAVIKTHIDILSDFSNETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHGGTLRISEWAHIINCSILPGEGIVEALAQTASAPDFAYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKYKNFVMGFVSTRALGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPGSAIGRGADFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGKLIL
Protein: Erythronate-4-phosphate dehydrogenase family protein (Q8VYC6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEEPCETLDSGEAYQISRYHNYNQHSSRSSSPWLDLRVFYVRISNFVVEDSTPEVLTINHIPLDPDTLLEINGVRMGMYSEGGSSQLRRDRVDKKSEEATYVSTDNIRLTGSVKFEVYDKNELVLSGTLEMSGSNGFTGESKNRWKMNCEAEVTAGSGFLKEKSINGQELSSPLPTIEVYVTGCFSGTPIILTKTLQLGLKKKQSRRMALDAIPEYETAEPQKDTSYALDLQATTEYGNYKEEYEGDMYWRSECIDGEMSWFNAGVRVGVGIGLGVCVGLGIGVGLLVRTYQSTTRTFRRRLL
Protein: Protein N-terminal amidase (NT-amidase) (EC 3.5.1.-) (O60178)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Deamidates N-terminal Asn and Gln. Component of a targeting complex in the N-end rule pathway (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- GID complex substrate-recognition subunit 10
Sequence:
MKFGCVQFFPKLGKVNENIVHLRQLLDQHSEALQSVKLLVFPEMCLTGYNFKNSESIQPFLENVTSNHCPSIQFAQEVSEQYRCYTIIGFPEFQNSNGISTLYNSTALISPKKELLNVYHKHFLFETDKSWATEGKGFSFEPCIPELGPISMAICMDINPYDFKAPFEKFEYANFILRELEHQQMVSSNVSRPIICLSMAWLVSDDKVIDASLPDIKNLHYWTTRLSPLINSNTDAIVLVANRWGKENDLNFSGTSCIMELSQGRAILHGVLKAAENGIVVGELEK
Protein: Abnormal embryogenesis protein 30 (P34441)
Organism: Caenorhabditis elegans
Function: Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in somatic and germ cells. Required for embryonic anterior-posterior axis formation. Negatively regulates ify-1 protein levels during meiosis I. Plays a role in regulating the abundance of glr-1 receptors in postmitotic neurons, which may in turn control animal locomotion. Involved in regulating GABA neurotransmitter release at neuromuscular junctions in GABA motor neurons.
Interaction partners:
- Cell division cycle protein 27 homolog
- Anaphase-promoting complex subunit 11
- Cell division cycle protein 23 homolog
- Anaphase-promoting complex subunit 2
- Cell division cycle protein 16 homolog
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit 1
- WD repeat-containing protein fzy-1
- Suppressor of spindle checkpoint defect 1
- Protein gfi-3
Sequence:
MDFSIVKTQILNNRRTFRTPFKVSSMCFSSQNDLIALGSKTGEILLKRTSWKMIWKTNINMIQAVGTECKLDSSVSALHFSPDGRFLAAATSKGIIHLLDVETGKVRFSVKAASEKIAKLHWNCVREKPFISNLGEFTTRIKNVEAIEGAIELAETTPNISQEEIAFVYQRLDEDGSSFKHEDAHKESLERTLISTETFRESLQNTILLATDDMDSKIIVLVAGVFPYMEIDISDTLLQYNQSLLMLYDMHYSSAFGGVSFLATTYGPFLDCKQNELKPPGAEPKKDGQGCHTLLFNVKLNINSSLWDTALRYIRLLFGFNLYSISLETTKRNWEEQIDNLHSLFDTKTKAVKIGNVLLEMLLSGSTDAAGEAFLERGLGTDGLDKIELFATKHMPEVCRIARGQLSTSARNLCFQRCEFSTSLSRYAKFIQLKDDDSFLYDEDPPAYLSESNIWLNTLEEKINILDMKTRHLGIQCLTMMQELGHLVKWISMTKPFAKTMKVNALMKIKRMNIAKILLYIVRNFIPDPEAVKDIENRLFNLKELVSKQKKKDLEDKFDEVEYLYRLERIAEVERKKLIETFHEKFRFADLDDDDLTPLLFQELDHPIDIFTDSMMEQNDSSPFLEEDEGEPEQEEQKPDEEPEPEGEPQPACDLDRVGSFFEKELSQKALEVLPKCDETFDCVLNERGSRMNSIEIQKMGILRVLEDLAATLSSPQKIHCDKAGNQKKLEVSFIYEITSTPTHQGYQDAKISSVTPSYYKRHPFNQLSGMGRSIQVSVLQKNEFSSIVIVPTSDVLPEDENEVNDHVEKLKRCYEFEKIDVTVDKSSAENRPPGETDAMEVDSNELRIDVDLGPVVPEYDTLIELSQVHPLHHGELVLLGKFTSAQEGTGVMSQMMRSISSYPHEIPEDKDVFAKNSSEDGSSEIPIETLIIHPTIQLAAYLHDDGSKITIGDMKPEVPPIADYEEKTVRKTFRDYQRRRERYREDMGVMNMNDVQYDVLVQEAMDSGRDLTDNGESDEDEEDDDI
Protein: Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4) (Q8VEA4)
Organism: Mus musculus (Mouse)
Function: Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes. Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17, COX19, MICU1 and COA7. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Required for the import of COA7 in the IMS. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system. Mediates formation of disulfide bond in MICU1 in the IMS, promoting formation of the MICU1-MICU2 heterodimer that regulates mitochondrial calcium uptake.
Subcellular location: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:Q8N4Q1}.
Interaction partners:
- FAD-linked sulfhydryl oxidase ALR
- Cytochrome c oxidase copper chaperone
- Mitochondrial import inner membrane translocase subunit Tim10
- Mitochondrial import inner membrane translocase subunit Tim13
- Mitochondrial import inner membrane translocase subunit Tim9
- Mitochondrial inner membrane protease ATP23 homolog
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import receptor subunit TOM40 homolog
- Apoptosis-inducing factor 1, mitochondrial
Sequence:
MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGDINWNCPCLGGMASGPCGEQFKSAFSCFHYSTEDIKGSDCIDQFRAMQECMQKYPDLYPQDEEEEEEAKPVEPVEETADTKVSAAKEQGTSS
Protein: Galectin (J3KS82)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPMPFITTILGGLYPSKSILLSGTVLPS
Protein: Transcription factor (F7EWM8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796}.
Interaction partners:
Sequence:
MYNSNYAGLVSNISLVAFPVSSTNSPTKILPKTLGPVNVNVGPQMIISTPQRITNSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPSDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNASNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPAVNSTIQLPFIVINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKIAKSLVPKALEGYITDVSTGPSWLNQGLLLNSTQSVSNLDPTTGATVPQSSVNQGLCLDAEVALATGQFLAPNSHQSSTAASQFSESRGETPCSFNDEEEEDEEEDPSSPE
Protein: Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (VLA-4 subunit alpha) (CD antigen CD49d) (P13612)
Organism: Homo sapiens (Human)
Function: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGA4:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Integrin beta-7
- Vascular cell adhesion protein 1
- Integrin beta-1
- Mucosal addressin cell adhesion molecule 1
- Fibronectin
- Paxillin
- Integrin beta-2
- Integrin beta-3
- Intercellular adhesion molecule 1
- Tetraspanin-8
Sequence:
MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYINSKSNDD
Protein: Transmembrane receptors / ATP binding protein (F4HR53)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Late embryogenesis abundant
- Uncharacterized protein F24D7.14
Sequence:
MESGVVSKPHRLKYDVFLSFRGADTRDNFGDHLYKALKDKVRVFRDNEGMERGDEISSSLKAGMEDSAASVIVISRNYSGSRWCLDELAMLCKMKSSLDRRILPIFYHVDPSHVRKQSDHIKKDFEEHQVRFSEEKEKVQEWREALTLVGNLAGYVCDKDSKDDDMIELVVKRVLAELSNTPEKVGEFIVGLESPLKDLTGLIDTESSSGVQVLGLYGMGGIGKTTLAKAFYNKIVGNFEQRAFISDIRERSSAENGLVTLQKTLIKELFRLVPEIEDVSIGLEKIKANVHEKKIIVVLDDVDHIDQVHALVGETRWYGQGTLIVITTRDSEILSKLSVNQQYEVKCLTEPQALKLFSYHSLRKEEPTKNLLALSKKIVQISGLLPLAVEVFGSLLYDKKEEKDWQTQLDKLKKTQPGNLQDVLELSFKSLDDEEKKVFLDIACLFLKMEIKKDEVVIVLKGCGLNAEAALSVLRQKSLVKILANDTLWMHDQIRDMGRQMVLKESREDPGLRSRLWDRGEIMTVLNNMKGTSSIRGIVLDFKKKFARDPTADEIVSRNLRNNPGIYSVFNYLKNKLVRFPAEEKPKSSEITIPVESFAPMTKLRLLQINNVELEGNLKLLPSELKWIQWKGCPLENLPPDFLARQLSVLDLSESGIRQVQTLRNKMVDENLKVVILRGCHSLEAIPDLSNHEALEKLVFEQCTLLVKVPKSVGNLRKLIHLDFRRCSKLSEFLVDVSGLKLLEKLFLSGCSDLSVLPENIGAMTSLKELLLDGTAIKNLPESINRLQNLEILSLRGCKIQELPLCIGTLKSLEKLYLDDTALKNLPSSIGDLKNLQDLHLVRCTSLSKIPDSINELKSLKKLFINGSAVEELPLKPSSLPSLYDFSAGDCKFLKQVPSSIGRLNSLLQLQLSSTPIEALPEEIGALHFIRELELRNCKFLKFLPKSIGDMDTLYSLNLEGSNIEELPEEFGKLEKLVELRMSNCKMLKRLPESFGDLKSLHRLYMKETLVSELPESFGNLSNLMVLEMLKKPLFRISESNVPGTSEEPRFVEVPNSFSKLLKLEELDACSWRISGKIPDDLEKLSCLMKLNLGNNYFHSLPSSLVKLSNLQELSLRDCRELKRLPPLPCKLEQLNLANCFSLESVSDLSELTILTDLNLTNCAKVVDIPGLEHLTALKRLYMTGCNSNYSLAVKKRLSKASLKMMRNLSLPGNRVPDWFSQGPVTFSAQPNRELRGVIIAVVVALNDETEDDDYQLPDVMEVQAQIHKLDHHKCTNTLHLSGVPRTNNDQLHICRYSAFHPLVTMLKDGYTIQVIKRNPPIKQGVELKMHGIHLVYEGDDDLEGRENTLPETQQTVSQKLANFFSSFEEEEGETISESESTVI
Protein: RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein) (Q15633)
Organism: Homo sapiens (Human)
Function: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
Subcellular location: Cytoplasm. Cytoplasm, perinuclear region. Nucleus.
Interaction partners:
- Endoribonuclease Dicer
- Protein argonaute-2
- Protein argonaute-1
- Interferon-inducible double-stranded RNA-dependent protein kinase activator A
- Trinucleotide repeat-containing gene 6A protein
- Ribonuclease 3
- Exportin-5
- Protein argonaute-3
- Microprocessor complex subunit DGCR8
- ATP-dependent RNA helicase A
Sequence:
MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK
Protein: endopeptidase La (EC 3.4.21.53) (Q72AU7)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
Sequence:
MARLSPLPARRLRATLDPARIHWETSDGIPRNGHRRPPQPRALQALELALHIRDGGYNVYLSGEPNLGRTYMLREFLAPRTRKSPTPPDLVYVNNFDDPDRPRLIELPAGQGRKLRAALIQALSRIRKEIPSRFENHAVVKKRAALLDKFQTVRSRLFKKMDDVATTQGFNLDMDDQGSLTLYPVIEGKRLSEEEFDKLDNGLRQSLKLKGDKLLQAMTGLMRQLTRAEQDFIEDERSLEREVARNVLDAVLTPVAERFAKACPGKDLPAFFAALRDDIIENLEGFVHRDAGLPHQAASGGDTPPSPFDEYRYDVNLFVDNSATTGAPIIVDDHPTPSNLLGCVERESEMGALVTDFTLIKAGSIHKANGGFLVLHMEDILQHPAAWEGLLRALRSGSARIEDPGDGQDTTKTKGIEPEPLTLRLKVVLIGTEDLYEALLESDDRFPKLFKLKAHLNDATERNAEGIRIYTHRMARIIDEAGLLPFDREAMAGLVDFGSRIIEDQRKLSLKFPLVRELMLEASAHAAMRGKKLVDRAVLDEALQGRVYRANLYEEHFMEEYDRELIKVKTDGEAVGRVNGLSVTWYGNFEFGLPHQISGTVGVGHGGIIDLEREAELGGPIHTKAMMILKSYLVDQFARNKPLVLTGSLCFEQSYAGIEGDSASGAELAALLSAISGVPIKLSLAFTGAVSQSGQIMAVGGVTRKIEGFFEVCCRRGLTGSQGVIIPQDNVDHLMLKQDIVDAVEQGRFAIYPVGHITDALELLTGLQAGRLRKNGKFTPGSLYDRVDRRLDELGRQAEHAFKKRR
Protein: Pcdha11 protein (B9EJ65)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MLSFQRRGSCTLPPLRWLLLLAAWEAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDTNDNPPVFPLREQRLLISESKQPDSRFPLEGASDADIGENAVLVYRLSQNEYFSLEPPINSKQTKRPSLILKKVLDREKTPELNLLLTATDGGKPELTGTVQLWVRVLDVNDNDPVFDHLEYKVRIMENAAKETLVITLNATDLDEGANGQLVYSLMSIKPTGRHLFTLDEKNGELRVNGTLDYEENKLYEIEVLATDKGTPPMVGHCVVLVEILDTNDNSPEVTLTSLSLPVREDAQPNTVIALISVSDLDSGINGQVTCSLTPNVPFKIVSTFKNYYSLVLDSSLDRERVSTYDLVVIARDGGSPSLSATVSVSVEVADVNDNAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLPHGAVGAGGAVSELVSRSVGSGHVVTKVRAVDADSGYNAWLSYEVQLGTGGVRSPFRVGLYTGEISTTRALDEVDSPRQTLLVLVKDHGEPALTATATVLVSLVESGQAPKSFSQASGRASAPEASLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPMVNEATGGPGKPMLVCSSEVGSWSYSQQRRQRVCSGEVLPKTDLMAFSPSLPPNLGRDERERQESESSHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPEPKKQTQVSFLPRRKGEASQPRQ
Protein: Endothelial cell-specific adhesion molecule (cDNA, clone cssl:d0254) (B0CLV1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MERRTSTKFHNYLSIFTFLCCFSSGELAQLVLPYENVDVIQGKMVVLQASYSSTDFQKNTVVWNYMQSATSTEMIISFVNGDFSHGTSQFAGRVGFFHNMPNTNLSLYINNTKVSDSGRYVCQVMIPGASGLTGTLNLNVKVPPSIPVCKVKEKPVLKANITLSCNSNEGKPAPKYKWIKTSPTSEVFFSPALNETAGTLKLNNLSSNMSGKYVCTSTNSAGEETCYINLEVITSTNAGMIAGVTFGCIVALILIVIFLIFMWTRRKDTEEDLANDIKEDAQAPKRVSWAKSGTGSDIISKNGTLSSIHTSSYPRDAHNHHHYPHSDTASIITATGSTAGYRSQPPVDATLERSLPGYNTNPAPTRGPFGPPSTNGGSQHTSMPRTAPAQPQIPRPPVLPTTVTAANISRMGGVPIMVPAQNQAGSLV
Protein: PDZ domain-containing protein (Q95QI3)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MPEVSVEKPLSVIPPEFCANANCPFSPKEISVLRIKVRGGVSKEEILQVNSASRPALPRQHSASTVSPLQSSSDELNNDSGIDNRTVGSPSTSEFSPRSTDLFVSPKSIIDEEPPHHPPPPPPVEEKLDQVLIPLKLSRGQDYAPIYRSLEQDTYYDQSPSESEKDEDLGLTNTKRYTENFRSVEKNQYMPVMSARVEATFKQPPPREGVKPFVSRAAQDITHNGESKVENIDLTIELNREQKATVTATKYPRTDFIMEDYHRPQTQILAPAPKKPNSTTRIYHAVDIPFDESPASYYPKQNNGYQRQRRYSASSASKQDGMFTLNVIMGSQPVHKGMGFSTVKRDERVIVESVIVGSPADKAGLLVGDTILSINGEEMSDKYQSGVTRILHEAARVGEADVLILRAPVPAPMLSKQMSTSSSNSSNYDKARSVFTENKSFDSYAEFKRKHTRTSRDSNSSNATRSSRDFNSLPRGTTAQSSLDRKRDTSLSSYRTAKDNFNSSSNRSSGRSEYGDYRVSNYQEKNAPGRLTDFVPEVDRRLSRREQSEEIYSRSQRDEEPRTIRNYHLSNENIARTNLNYDGRRDSEEESTTTTLKRTTLPRSGTAQWKNEYSDGEEVTEKLPVTSRDSSPLRSALKKSSHNYYHQSSDPVAPPPRRYYSTESLQLPKTSSYQRYSEEEDEEIEETYSSMRRHRQEIPRHVDEFHTVGSYGVMPQRSRSQQPARLPRYDSVPDDVDEVSGVSHRFYDRSGNHVRAPRERIHDIQIQRDYGDRAPSRDLDFVRNTYKWEEQLEDTKVTTTTKIYEKESRDWRDVINQQRQAAPGNSADRRGIAATSSSLSNLPSYINRRMEKEREREIEYRRDREYSMPPADPPVITEKYERDEYSRVEERTYPVPVARNKMRREETQMQSSLQQMHSQSSQKDDSVVAVSGKHRCAHCNEELGRGAAMIVESLNLFYHLACFKCYVCKTSLGSGATGADVRVRDGRLHCQTCYSNDRVQLSKV