wanglab/gogpt-training-data huggingface dataset:
Protein: Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (EC 3.1.1.6) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Q64285)
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P19835}.
Interaction partners:
- Pancreatic triacylglycerol lipase
- Chymotrypsinogen B
- Inactive pancreatic lipase-related protein 1
- Carboxypeptidase A1
- Chymotrypsin-like elastase family member 3B
- Chymopasin
- Pancreatic lipase-related protein 2
- trypsin
- Anionic trypsin-2
- Chymotrypsin-like elastase family member 2A
Sequence:
MGRLEVLFLGLTCCLAAACAAKLGAVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFATAKTLENPQRHPGWQGTLKATNFKKRCLQATITQDNTYGQEDCLYLNIWVPQGRKQVSHNLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGMALSPWAIQKNPLFWAKTIAKKVGCPTEDTGKMAACLKITDPRALTLAYKLPVKKQEYPVVHYLAFIPVIDGDFIPDDPINLYNNTADIDYIAGINNMDGHLFATIDVPAVDKTKQTVTEEDFYRLVSGHTVAKGLKGAQATFDIYTESWAQDPSQENMKKTVVAFETDVLFLIPTEIALAQHKAHAKSAKTYSYLFSHPSRMPIYPKWMGADHADDLQYVFGKPFATPLGYRPQDRAVSKAMIAYWTNFARSGDPNMGNSPVPTHWYPYTLENGNYLDITKTITSASMKEHLREKFLKFWAVTFEVLPTVTGDQDTLTPPEDDSEVAPDPPSDDSQVVPVPPTDDSVEAQMPATIGF
Protein: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Q580K8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DPH-type MB domain-containing protein
- Elongation factor 2
Sequence:
MEAELGLPSNYRFEIEKCARRIREKGATRVALQFPEGLLMFAAPIADILEEQTGAEMVILGDVTYGACCVDDYSALALGCDFLIHYGHSCLISIKDCLIKNMMYVFVEIDIDVQHFVDTVRSLVPPETRLACIATIQFVSSMRAGVQMLENHFHQPVVVPQNKPLSRGELLGCTSPVLDPTAVDLVLYVGDGRFHLEAFLIAHPTLNALQYDPYKKTMTTESYNTSEMRTLRREAVQLGKAASSFALIMGTLGRQGNPRLVDRIMQLAEKRGKTVTLFLMSEIFPQKLARIQDVDCYIQVACPRLSIDWGYAFDKPLLSPYEAEVALGNVNWNDVHYPMDHYSKDGGKWAVYTNKSL
Protein: Zyxin (C9IZ41)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPF
Protein: NAD(P)H-quinone oxidoreductase subunit J, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit J) (NADH-plastoquinone oxidoreductase subunit J) (P0C339)
Organism: Oryza sativa subsp. indica (Rice)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01357}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01357}; Stromal side {ECO:0000255|HAMAP-Rule:MF_01357}.
Interaction partners:
- NAD
- NAD
- NAD
- NAD
- 4Fe-4S ferredoxin-type domain-containing protein
- Uncharacterized protein
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NAD
- NAD
- NADH dehydrogenase 1 beta subcomplex subunit 7
Sequence:
MQQGWLSNWLVKHEVVHRSLGFDHRGIETLQIKAEDWDSIAVILYVYGYNYLRSQCAYDVAPGGSLASVYHLTRIQYGIDNPEEVCIKVFAQKDNPRIPSVFWIWRSSDFQERESFDMVGISYDNHPRLKRILMPESWIGWPLRKDYITPNFYEIQDAH
Protein: FA complementation group L (C9JZA9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAVTEASLLRQCPLLLPQNRSKTVYEGFISAQEVALKNRQELYALPPPPQFYSSLIEEIGTLGWDKLVYADTCFSTIKLKAEDASGREHLITLKLKAKYPAESPDYFVDFPVPFCASWTPQSSLISIYSQFLAAIESLKAFWDVMDEIDEKTWVLEPEKPPRSATARRIALGNNVSINIEVDPRHPTMLPECFFLGADHVVKPLGIKLSRNIHLWDPENSVLQNLKDVLEIDFPARAILEKSDFTMDCGICYAYQLDGTIPDQVCDNSQCGQPFHQICLYEWLRGLLTSRQSFNIIFGECPYCSKPITLKMSGRKH
Protein: Polybromo (Q9VC36)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Supporter of activation of yellow protein
- GH08712p
- Brahma associated protein 170kD
- Brahma associated protein 55kD
- Brahma-associated protein of 60 kDa
- Bromodomain containing 7/9
- Brahma associated protein 111kD
- Brahma associated protein 155 kDa
- ATP-dependent helicase brm
- Barrier-to-autointegration factor
Sequence:
MLSRKRRASSISSRQDEDPLQLDDSTPEQSPVQQTTTQSARKKRRLDPTELCQQLYDSIRNIKKEDGSMLCDTFIRVPKRRQEPSYYDVVVNPIDLLKVQQKLKTDSYDDLDDLMADLELLIGNAKAFYIPGSSEHQDAVSLWQHIHSQRQRIMEANGLAEEEPRARRMSRQVRRMTSSTEPGGDGATDDEYNQYEELFASVMTATDPVGDRLMHRMFQLLPSKKIYPDYYDVIEHPIDLRLIATKIQMNAYSSLAEMERDLLQMTKNACLFNEPGSQIYKDAKSLKRIFTQRRIELEMGKGKLAKRVKSLSSAAIAALKEEVDSSDDEETSKKGEGPMWALFDHLYNAPGTSEHPGVTGPPLGNSLWKLPVRRFHPEYFELIKRPISMSQIHTKLKKGDYANISDLTADLYLMLDNAKKAFPTSHRTHKDALKMLKLMNAKLVEESLEEGSDLDDEDAEEMDTEVFTVSTQPEKRKPGRPRINSNSNSNASHTPNNSNSPKSNRIAINAAIKKKILSIQKYLVDYSLGNRRPIEMFMEKPPRKIYPDYYDIIQNPIDMNTIEHNIRTDRYAAVEDVVSDYRLMFSNCRQYNEEGSNIYEDANILERALNEKLKEFPGLTEGKKSQQKYSKVGRKLKTAVITERLWQFYETVKEYQEPKGKRQLSLIFTKLPSKSEYPDYYDIIREPIDMDRIAQKLKQGAYDTLDDLAADFLLMLENACKYNEPDSQIYKDALVLQQLTLQLKQQLRTERDSLPDVPLAVQELFLTLFTTIYNHQDEEGRCYSDSLAELPEYDEIGEGPKVRGISLDLVKRRLDKGAYKRLDVYQEDIFACLERARKLSRTDSDIFQDSIELQTYFIRKRDELCKDTLSSSALNFSLERLMADVELCRQQKMQQEEQDQEQDKEKDEFNAAKGESMTINQQVFSPGDYVYVQMPENKIPSICCIERLWTSPTNEKLMQASIFVRPHETYHVTTRKFLEKEVFKSSLSQTISMDKVQGMCYVMNIKDYIKMRPENLPEKDVYVCESRYNIQGRWFKKLKSWPPVREGSSVKFVPREQPLELKRVMSVFKERLEKHKGELEELKLQETLVEKEKPNVSCDPPPNAEVGSTYYQQYNTICSGAIKTGDFVYVATQTGKQSVAQVQQIWEQNGKSYFKGPWLLPPSETTPGLGKQFYRQELLLSTVEEVSPVVGIVGRCAVLEYSEFISSRPTEISESDVYICESVYDELKKALRKLVTGNMRKFQHSPSVTEDEIFYFKTPIKPSKDFKNELNELGMLEDSMDGDTPSLSSDIAAMSSPAPSVNSTPLTSKVKAAKSAKKCLTGYILYSSEVRKSICQSNPDATFGDISRMVGTEWKNLPSSVKQSWEDRASRQNEETAALRRELDDVQNSASPSSQVSQDVFGQVLTFECQWDKCDFQFEELSDCTEHCMSDSTGHIQRHPQAGVETEYVCLWRNCPRVKKSVQAFPNVLRLIKHVREVHLSKCGKTISAADRSKNFVPRRQKHAQLATTVPIPPSLAQSPRAPSNLEAVQLQQQQHPQQNMHQLQQQQTIVLGPPPEPLFVTVPPRTTRVIHSEAYIKYIESLQTGSHLNVVTCNNNWRRALTHITPAQVVAKTALPEKWIGPNLRDQGNVVQALCHLRNFMVDDILQIRRSCN
Protein: Developmental pluripotency-associated protein 3 (Stella-related protein) (Q6W0C5)
Organism: Homo sapiens (Human)
Function: Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process (By similarity). Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation (By similarity). Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark (By similarity). Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis (By similarity). May be important for the totipotent/pluripotent states continuing through preimplantation development (By similarity). Also involved in chromatin condensation in oocytogenesis (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:21421998}. Cytoplasm {ECO:0000269|PubMed:21421998}. Note=Mainly localizes in the female pronucleus, localization to the male pronucleus in much weaker. {ECO:0000250|UniProtKB:Q8QZY3}.
Interaction partners:
- Developmental pluripotency-associated 5 protein
- Homeobox protein NANOG
- POU domain, class 5, transcription factor 1
- PR domain zinc finger protein 1
- Protein lin-28 homolog A
- Protein lin-28 homolog B
- Zinc finger protein 57 homolog
- Krueppel-like factor 4
- Transcription factor SOX-2
- Undifferentiated embryonic cell transcription factor 1
Sequence:
MDPSQFNPTYIPGSPQMLTEENSRDDSGASQISSETLIKNLSNLTINASSESVSPLSEALLRRESVGAAVLREIEDEWLYSRRGVRTLLSVQREKMARLRYMLLGGVRTHERRPTNKEPKGVKKESRPFKCPCSFCVSNGWDPSENARIGNQDTKPLQP
Protein: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) (P21914)
Organism: Drosophila melanogaster (Fruit fly)
Function: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- RH44771p
- AT18465p
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase 23 kDa subunit
- AT02348p
- ATP synthase subunit gamma, mitochondrial
Sequence:
MLATEARQILSRVGSLVARNQMRAISNGTAQLEQQAQPKEAQEPQIKKFEIYRWNPDNAGEKPYMQTYEVDLRECGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNIGGTNTLACISKIDINTSKSLKVYPLPHMYVVRDLVPDMNNFYEQYRNIQPWLQRKNEAGEKKGKAQYLQSVEDRSKLDGLYECILCACCSTSCPSYWWNAEKYLGPAVLMQAYRWIIDSRDENSAERLNKLKDPFSVYRCHTIMNCTRTCPKGLNPGRAIAEIKKLLSGLASKPAPKLETAALHK
Protein: Caerin-1.16 (P86503)
Organism: Litoria rothii (Roth's tree frog) (Hyla rothii)
Function: Antibacterial peptide with wide spectrum of activity. Induces contraction of intestinal smooth muscle in isolated guinea pig ileum through binding to CCK2R. Induces proliferation of mouse splenocytes. Has no activity through opioid receptors.
Subcellular location: Secreted {ECO:0000269|PubMed:16124032}.
Interaction partners:
Sequence:
GLFSVLGAVAKHVLPHVVPVIAEKL
Protein: Protein argonaute-2 (O16720)
Organism: Caenorhabditis elegans
Interaction partners:
- Endoribonuclease dcr-1
- Protein lin-41
- ALG-1
- ALG-1 INteracting protein
- Protein argonaute-1
- Piwi-like protein ergo-1
- DRBM domain-containing protein
- Hyaluronan/mRNA-binding protein domain-containing protein
- Staphylococcal nuclease domain-containing protein 1
- Ribonuclease 3
Sequence:
MFPLPVHNGPRLGKLSIFEMPGDSLTSSSFMPDGGAETSSSSQLGGSAHGAIGTKPDAGVQFQCPVRPNHGVEGRSILLRANHFAVRIPGGSVQHYQIDVFPDKCPRRVNREVIGCLISSFSKYFTNIRPVYDGKRNMYTREPLPIGTEPMNFEVTLPGDSAVERKFSVTMKWIGQVCLSALDDAMEGRVRQVPHEAVQSIDVILRHLPSLKYTPVGRSFFTPPGVMKPGMQMHQESKLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYRAMPVIEFVAEVLELPVQALAERRALSDAQRVKFTKEIRGLKIEITHCGAVRRKYRVCNVTRRPAQTQTFPLQLETGQTIECTVAKYFFDKYRIQLKYPHLPCLQVGQEQKHTYLPPEVCDIVPGQRCLKKLTDVQTSTMIKATARSAPEREREICKLVSKAELSADPFAHEFGITINPAMTEVKGRVLSAPKLLYGGRHRATTALPNQGVWDMRGKQFHTGMEVRTWAIACFAQQSHVKENDLRMFTTQLQRISTDAGMPIIGTPMFCKYASGVEQVEPMFKYLKQTYSAIQLIVVVLPGKTPIYAEVKRVGDTVLGIATQCVQAKNAIRTTPQTLSNLCLKMNVKLGGVNSILLPNVRPRIFNEPVIFLGCDITHPAAGDTRKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIITDLTYMVRELLVQFYRNTRFKPARIVVYRDGVSEGQLFNVLQYELRAIREACVMLESGYQPGITFIAVQKRHHTRLFAADKADQVGKAFNIPPGTTVDVGITHPTEFDFFLCSHAGIQGTSRPSHYHVLWDDNDLTADELQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDRDHGSGEEGSQPSGTSSEDTTLSSMAKAVQVHPDSNNVMYFA
Protein: Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor) (Y2 receptor) (P49146)
Organism: Homo sapiens (Human)
Function: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Pro-neuropeptide Y
- Peptide YY
- Pancreatic polypeptide prohormone
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Pro-opiomelanocortin
- Peripherin-2
- Melanin-concentrating hormone receptor 1
- Glucagon-like peptide 1 receptor
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
Protein: Hemoglobin-beta (Q6S9E2)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Interaction partners:
Sequence:
MVHWTDAERHIIADLWGKINHDEIGGQALARLLIVYPWTQRYFSSFGNLSNAAAIIGNPKVAAHGKVVLGGLTKAVQNLDNIKGIYTQLSTLHSEKLHVDPSNFTLLGDTFTVTLAANFGPSVFTPEVHETWQKFLNVVVAALGKQYH
Protein: Serine/threonine-protein kinase psk1 (EC 2.7.11.1) (Ribosomal S6 kinase homolog psk1) (S6K homolog psk1) (Q12706)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: AGC kinase which plays a role in TOR complex 1 (TORC1) signaling pathway which mediates temporal control of cell growth in response to nutrients. Required for phosphorylation of ribosomal protein S6 (rps601/rps602) at 'Ser-235' and 'Ser-236'.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein eS6B
- cAMP-dependent protein kinase regulatory subunit
- Serine/threonine-protein kinase tor2
- Small ribosomal subunit protein eS6A
- Serine/threonine-protein kinase tor1
- Mitogen-activated protein kinase spm1
- Mitogen-activated protein kinase spk1
- Serine/threonine-protein kinase sck2
- Serine/threonine-protein kinase sck1
- Mitogen-activated protein kinase sty1
Sequence:
MPVFMFDEHDNLNENYNSHLSSDDEIAEEGYDFEELEASASTITSSSDLKDGKNAKDEKGTVEFKVAAHGDFISSKGDNYVPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENFSVEFTKLPLSTTPILHEEFGNLTIGSHSSAFQGFTYVASPNFLNCEFLSNNAVSNH
Protein: Phosphoinositide 3-kinase regulatory subunit 5 (J3KSW1)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVANKLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELASGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDILQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP
Protein: Lamin A (Lamin isoform X1) (B3DKC5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus lamina {ECO:0000256|ARBA:ARBA00024186}. Nucleus matrix {ECO:0000256|ARBA:ARBA00004109}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
METPGQKRSSRGGVTNVLSPTRISRLQEKEDLSNLNDRLAVYIDKVRSLEVENAGLRMRITESETEISRELSGMKAAYEAELADARKTLDSVAKERARLQLELSKVREDYKELKARNGKKEADLESALARLKDLESLLNSKDASLSTALGEKRTLEVEVRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYSEELRESKRRYESRVVEIDSGRQQDYESKLADALTDLRNQHEEQLRIYKEEIEKTYNSKLENARSSAERNSHLVGAAHEELQQTRVRMEGVSSQLSQLQKQLAAREAKIRELEEALSRERDILRRRLEDKEKEMAEMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPARGVTVTRSSGSGSHTRVVQSSTSRTSSGSAKKRRLNDNDSDASSVVGGTVTRTRISQQASASGRVTVDEVDLEGKFVRLNNKSDQDQSLGHWQVKRQIGSGTPIVYKFPPKFNLKAGQTVTIWAAGAGGTHSPPSDLVWKTQNSWGSGDLFQTTLISSSGEEMAMRKVTRTLFQDEEDDEMAAHSTCGDSEYNLRSRTVLCGSCGQPSDRNSSCVSASSGVSSASRSFSSGGGGGLTEAFVSPSHFIVSNDKPRQAGPKVDNCSIM
Protein: TY1 enhancer activator (P47988)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: TY1 element enhancer binding protein. Binds to the DNA sequence 5'-TCGGTGGTATTATTCCGA-3'.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MTAPLWPNKNEKNHTVKRALSTDMTSNILSSTNASSNEENSRSSSAANVRSGTGANTLTNGGSTRKRLACTNCRNRRKKCDLGFPCGNCSRLELVCNVNDEDLRKKRYTNKYVKSLESHIAQLETNLKNLVQKIYPDDEQILNRMMVGDVLSALPDSSQVSINYTDQTPSLPIPATRGTFIIENDKVSQPLSSFNQQTEPSTLNSGIFNTQKQNFEESLDDQLLLRRSLTPQGEKKKKPLVKGSLYPEGPVSYKRKHPVKSDSLLPVSSLTAATDPSTFSDGITAGNSVLVNGELKKRISDLKTTVIVRGLNDDNPNSINNDPRILKSLSNFYKWLYPGYFIFVHRESFLYGFFNHSKNNYEDSSYCSVELIYAMCAVGSRLTPDLQEYSEVYYQRSKKTLLQLVFDEQSTARITTVQALFCLAFYELGKGNNQLGWYFSGLAIRVGYDMGFQLDPKVWYVDDNNLQLTQSELEIRSRIYWGCYIADHFICLMLGRTSTLSVSNSTMPESDELPEVNGTEEFRFIGRHVLQISLPLKNLIILSRLVQIFTSKIFIESEDIARKLKYLNTFNSQVYNWRQSLPEFLQWSKTLIENDDVSTDPTISYFWYCYYIVRLTFNKPFIEDSQESETVVIEIIDDLKTLLDNFGKKFGNYTKGNLYQLYSCLLAINCLKKLKEIRSSEQDSWNAQLDFFNHIFYTQLYPAYDLPKKLQEDTELETEQENQMLNQVGNINYTHDFSLSHEIDDLIRELFGVGTPQKL
Protein: D-glucuronyl C5-epimerase B (EC 5.1.3.17) (F1QR43)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. Plays a role in dorso-ventral axis specification during early development, together with glcea, where it may potentiate signaling via the BMP pathway.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9EPS3}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9EPS3}.
Interaction partners:
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
- [heparan sulfate]-glucosamine N-sulfotransferase
- [heparan sulfate]-glucosamine N-sulfotransferase
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
- heparosan-N-sulfate-glucuronate 5-epimerase
- Heparan-sulfate 6-O-sulfotransferase 2
- Sulfotransferase
Sequence:
MMRCLAARVHYKTLIVICALLSLLTVLLWNKCTSEKALRFLPRHPQPPPSPKIDSHPQQPQPPEPPPVVGGVRYEEIDCLINDDATIKGRREGSEVYMPFSWMEKYFEVYGKVVQYDGYDRFEFSHSYSKVYAQREQYHPNGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYAIQIAQYGLSHYSKNLTERPPHVEVYDTAEERDSRSSAWTVPKGCSLTRVYDKTRATSVRQFSAPENSEGVSLPLGNTKDFIISFDLKFTSNGSVSVILETTEKGPPFVIHYVTTTQLILLKDRDITYGIGPRTTWTTVTRDLLTDLRKGIGLSNTKAVKATKTMPRRVVKLVVHGTGTIDNITISTTSHMAAFYAASDWLVRNQDERGGWPIMVTRKLGEGFRALEPGWYSAMAQGQAMSTLVRAYLMTKDDTYLKAALRATGPFKLPSEQHGVKAVFMNKYDWYEEYPTIPSSFVLNGFIYSLIGLFDLAQTAGEKLGRDAGQLYSKGMESLKVMLPLYDTGSGTIYDLRHFILGTAPNLARWDYHTTHINQLQLLGTIDNSPIFRDSVKRWKSYLKGGRAKHN
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BRCA1) (Q90Z51)
Organism: Gallus gallus (Chicken)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDLSVIAIGDVQNVLSAMQKNLECPVCLDVIKEPVSTKCDHVFCRFCMFKLLSRKKKGVIQCPLCKTEVTKRSLKENSRFKQLIEGLLEAISAFELDTGVKFLSSRYFPKTSTEVATAELLGNNSSVIQSKGFRNRKRGAKENRQDSCTLEANVDPQLTDNRVKGSSVRSKKQKCGIEKGVLIELGTDSSEEHFILASSTGLEDKEELEEPKSAEKYGSSCNTQPLKLGAKEIILPNVIGETDFLKEALDKKSMLNITEHIKCNQVNTIEGQSSPLNVFDADLLTGQRDGIGNASPLKNDTSFLKNAEEMDVEETQCSHKNQELDLEDSSEGRLDKIKEKDICVPSVEDVEMCEPMDDSLLEKEPPVEKPLQPKIPHCPTLNEVSTKGLNQSIQKVNEWFSKSSRILSSSSSQNDHAEATDASGEGDISLSDKDSCISEKTNPIVDSVEFAVIERNKRWTKQTTYSIEDKIFGKTYERGRKSNPSTILRDILPATKKEDAAAEEGCLNNSRKDRLKRKRKSACILQPEDFIKKKDLEEADRCPQGIKSSLGDAEKEKCDENSAVKENPLLEKRKGSTLAEFKERGLQWKNAAEKVSGKCSDGQLELNNSDQKSTKNACSTAKGCRHSTRTRCAIHLVDRNPGSFDLAEPLINSYPSNEEPSKADCERRQVRRSRRLQLLSEEITKETGKMRVIKEAKNSDSGPEGSVFGVERNVLVHNSQCKDLRKQQDILSYMSLADRNGADLEANGIQISSKNSDDMAKNRSFFNPTFSCQLSNFNSPSSKAGSQEGEMLGKLFLPQSPSKTVLHAASILTEEKRSWSCTVFSQDKGCCSRNVPKDFRIGKSPMAKNASEFTMEAEDSELDMQYLRNIFRSSKRQSFSLYPTPMKACTTDDVASEKLNTSCPDQVEERNSKYLKTENLQEEKTTAENLSSVCEKFETCESACVSPVSCFVSSAACVHTVENQDVSKVANHGNLTTLLRICAARNEDGNRPQKGEQGSEKTLSTGIGVESKLRLSPVRSNRSQSDQSNTEEHAFQRTGLNAVSETYFSSESNQVEKAEVVDDKGLMQHFQPSPMLCPTACQQNPAEFNCELTEKKIITRERSLVKGNEERVIQTVSTGLSEFSVREALEESLKGHSDFTDLSETPDGLLCSDNDTEESASFYVTNRKDTSAVFVKRSGAAWVKEVNDSVVSCKPRSEGIQRFRRRAQKLQSSDEESSDDEDLPSFQELMFGKSVSTPLQIQKQVTSVVQSSANPSTLPCSECLNENNEQKTLEAALSNECASPSQESECSVNLFSSQSNMSEESVDGAQELKKTLTQVSNVKKSKEAPQSCSGGLKRLKNNLNDEYQEDPNMGANLGEASGYDSETSRVEDSHEPFSQGEILSTQQKNAMQNNLKKLQQEMAVLEAVLKQHGSQDAEVLPLCRELPYCSIGGTLGLERMRQETENVSEHDSETKLTKASVLPVLCGNVTKNPNSSSFSVKHPCPQTAEATDSSAVAQGDNKSNVQVCKSKRSVCFPTSVLHNVAGKENAASSGTTCRTEMSIVASGLNQSEHLMVQKFARKTQSTFSNHITDGTTHVIMKTDEELVCERTLKYFLGIAGRKWVVSYQWIIQSFKEGRILDEEHFEVKGDVINGRNHQGPKRARQSPAEKIFKDFEICCCGPFTDMTTGHLEWIVELCGASVVKQLHLFTHKVNSTAVVVVQPDAWMEGTSYEAIQRKNNVAVVTREWVLDSVACFECQELDAYLVSQD
Protein: Meiotically up-regulated gene 130 protein (Q9UT31)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MICKYIYLAIFVFGTARIPKPSACLPGDFWKTKQEIEVQKKIDEFNQYRISALWSMVSKMEDPTLSGLDGRYIVVDQNQLYLSPISKKSEKLIFRFNLNHRGYLEVKSGFRAFIENKYSPLVFHATSWTNGFSIDVQKTNPISSYTPFVMQYLNSPWFSACRVESGNWQVFVGRMNMNEHEHCYPMSLIMKREDTWLRYYHKNNRNPIDWKLVQDCAMWPDGYPGTGRESEKGSNLEAITR
Protein: Uncharacterized protein (Q382D6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLLKKLPVFVGTEFLTDAHLAIMTSGGVSIPLEMESRCKELHPNHRVPYVLSRLAASSALSTVLGKPITFSGSRHDAEQYDANLSLSHEDFVGAAVAWRKGTSNAIGIDVVDVQQLERVVKRFPQFAARFMPRCDLSALSSVDACNIERTFRGHADQVTVTLSQHWGLRECCVKLVGVEGRTFPFECFRGPRAYFPDRFKAQVVEEGSDALRAAGLNSSLFVSTWPELLKLPSGDVKPYIVVVAACPRKSAV
Protein: Neurofilament light polypeptide (Neurofilament triplet L protein) (Q29RE8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSSMSYNPYLPSVQRRRIVVRSGTPFGGGSSRSRSVYSTYSSPSRASVLSSGAGLHLSAASADMELSQATQLSSEFKQVRTQERAQLQDLNDRFVSFIERVHGLELQNRALESELLLLRQRHCEPSRLRGLYEQEARELRAAVDEARRERQAAQERRDRLEEALKALQSRYEEEVLAREEAEGRMMDARKGVDEAALARSELEKRADTLLDELAFLKRLHESEIAELQAQVQYTAQVSVEMEVAKPDLSVALRDIRGQYERLAQQNIQAAEEWFRGKVSTMAEDTAKHTENIRTAKDEAGEYRRLLKARDLEIEACQGLNQVLERQLQEVEEKQSAEIAALQDTIGDLENELRTMKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRFNVGGIGGISSVFSPSIAATPSFGRPVFSVQASLTSGAPYLLGTRLMSYSASPYEIIEATQAQEAEASPEKEEEEEEEEEQQEEAEEGEEEKEEEEEEGEKEEEEEEEKEEEEKEEGEEGGEEGGEEEGEQEEEGEEEEGKEEGGEEGDEGEEDEAEKDDAGKEEEKKKGGEEKDSKAEKAKPKEK
Protein: Putative F-box protein At3g24580 (Q9LV45)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Iron-sulfur cluster assembly protein 2
- Iron-sulfur cluster assembly protein 3
- Iron-sulfur cluster assembly protein 1
- Frataxin, mitochondrial
Sequence:
MTKMSNLPNDLAEEVLSRVSLTSLRNVRLTCKDWNTLSKGESFAKNHLGYQAIVAAKEKEFMMVLMMDFRVYLIRVNVHNDIESCIKPEGELISLGDEVDVSQVFHCDGLLLCITEDNEDNAKVVLWNPYWGQTRWIESTNNFHKLDMYTYALGYKKSSKSSRSYKILRFIDFSPTCSEFKIYNINSDSWKVLDVSPDWKIDSYIRGVSLKGNTYWIARERHGYGHTFLVCFDFTRERFRSRLPLPSQPCVLDTVSLSSVREEQLAVLFQCSSTLEMQIWVTTKIEPNAVLWNSKVFLAVDMHSLKFQFQVRASSFFIDEEKRVVVVFDKEKRYLASSRNKAYIVGVDGTWEQVDLGMSVDKFVYPLVCSYVPSLVHF