wanglab/gogpt-training-data huggingface dataset:
Protein: Mastermind-like protein 3 (Mam-3) (Q96JK9)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:12370315}. Note=Nuclear, in a punctate manner.
Interaction partners:
- Recombining binding protein suppressor of hairless
- Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 3
- Neurogenic locus notch homolog protein 4
- Neurogenic locus notch homolog protein 2
- Recombining binding protein suppressor of hairless-like protein
- Mastermind-like protein 1
- Mastermind-like protein 2
- Histone acetyltransferase p300
- Ankyrin-1
Sequence:
MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYERNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
Protein: Interleukin family protein (Q5EFQ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU368043}.
Interaction partners:
- Interleukin 10 receptor, beta.
- Interleukin 13
- Cytokine receptor family member b4.
- Lymphotoxin-alpha
- Interleukin-1.
- Forkhead box P3
- Interleukin-6
- Arginase
- Toll-like receptor 2.
- Myeloid differentiation primary response protein MyD88
Sequence:
MIFSGVILSALLTLLLCDCAQSRRVECKTDCCSFVEGFPLRLRELRSAYKEIQKFYESNDDLEPLLNEDIKHNINSPYGCHVMNEILHFYLETILPTALQKNPLKHSTTPIDSIGNIFQELKRDMVKCKRYFSCQNPFEVNSLKNSYEKMKEKGVYKAMGELDLLFRYIEQYLASKRVKH
Protein: HTH-type transcriptional regulator NimR (Regulator of nimT) (P76241)
Organism: Escherichia coli (strain K12)
Function: Negatively regulates expression of the nimT operon and its own expression. Acts by binding to the nimR-nimT intergenic region.
Interaction partners:
- 2-nitroimidazole transporter
Sequence:
MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLILALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANAELCFLFIEPSAVTMPTTCCTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKIRTMVEMMAKGPVEWGALGQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQGLVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIARLTTVSPQSAKPDPRQ
Protein: Kelch-like protein 10 (Q9D5V2)
Organism: Mus musculus (Mouse)
Function: May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. Required for male fertility.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15136734}.
Interaction partners:
- Cullin-3
Sequence:
MEMESTAASTRFHQPHMERKMSAMTCEIFNELRLEGKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISVLLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVGEYAARRDNFTGLALRDEVKYSASTSTLPV
Protein: Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3) (O95045)
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable). Shows broad substrate specificity and accepts uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
Interaction partners:
- Thymidine phosphorylase
- Cytidine deaminase
- Purine nucleoside phosphorylase
- Dihydropyrimidine dehydrogenase [NADP
- Uridine 5'-monophosphate synthase
- Uridine-cytidine kinase-like 1
- Uridine-cytidine kinase 1
- 5'-nucleotidase
- Uridine-cytidine kinase 2
- Uracil phosphoribosyltransferase homolog
Sequence:
MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGLCD
Protein: Chloroplast protein FOR GROWTH AND FERTILITY 2 (Q9SLD9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Together with CGF1, essential protein which supports female gametogenesis and embryogenesis, probably by securing local energy supply.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:32306898}; Multi-pass membrane protein {ECO:0000255}. Plastid membrane {ECO:0000269|PubMed:32306898}; Multi-pass membrane protein {ECO:0000255}. Note=Present in chloroplasts on green tissues as well as in plastids of roots and seeds. {ECO:0000269|PubMed:32306898}.
Interaction partners:
- Copper chaperone for superoxide dismutase, chloroplastic/cytosolic
- Protein TIC 21, chloroplastic
- Solute carrier family 40 member 3, chloroplastic
- Annexin D7
Sequence:
MDRLLQPPSSHSIAPSKFQSRPSPLLLHRLHSTNLSTFPSSRRLESRRISSISCFFRQNPSPDTSPGLNQSSNFLIASSQTDASKPNPGFIQRIVSSFEQRKTISAGMVILVSAIAALLLNPILVPPAFASFQTATNSGGAAVVGGKLLRTEVLTSAWTGFFAGCLHTLSGPDHLAALAPLSIGRTRMESAAVGALWGCGHDAGQLIFGLLFLLLKDRLHIEVIRTWGTRVVGLTLLVIGAMGIKEASEMPEPCVVTLENGETDEKSLKKKKIGFATFATGIVHGLQPDALMMVLPALALPSRIAGASFLIMFLIGTVIAMGSYTVFIGSCSEALKEKVPRITEKLTWASSLVAIGLGLAIIVSQFFGFSLY
Protein: Tetratricopeptide repeat protein 9A (TPR repeat protein 9A) (Q3V038)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MERKGLAARSSGNPSPPALGEGPRPVPPPCVPSGGGAPERGQAGTAAEPAELIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPSQEERDARPASSAGVPKSSRLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTRQPTDTNVIRYIQLTEMKLSRCSQREKEAM
Protein: Amphoterin-induced protein 3 (AMIGO-3) (Alivin-3) (Q80ZD5)
Organism: Rattus norvegicus (Rat)
Function: May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAWLVLLGLLLCMLGAGSGTSDLEGVLPPDPHNCPNKCVCAADVLSCAGRGLQDLPAALPATAAELDLSHNALKRLHPGWLAPLSRLRALYLGYNKLDVLGRGVFTNASGLRILDLSSNLLRRLRTYDLDGLEELEKLLLFNNRLMHLDLDAFQGLSMLSHLYLSCNELSSFSFNHLHGLGLTRLRTLDLSSNWLGHVSVPELAALPTFLKNRLYLHNNPLPCDCSLYHLLRRWHQRGLSALHDFEREYTCLAFKVAESRVRFFEHSRVFKNCSVAAAPGLELPEEELHTHVGQSLRLFCNTTVPAARVAWVSPKNELLVAPGSQDGSIAVLADGSLAIGRVQEQHAGLFVCLASGPRLHHNQTLEYNVSVHKPRPEPEAFNTGFTTLLGCIVGLVLVLLYLFAPPCRGCCRCCRRACRNRCWPRASSPLQELSAQSSVLSTTPPDAPSRKASVHKHVAFLEPGKKGLNGRVQLAVAEDFDLCNPMGLQLKAGSESASSTGSEGLMMS
Protein: Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Uridine monophosphokinase 2) (Q9QYG8)
Organism: Rattus norvegicus (Rat)
Function: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor.
Interaction partners:
- Uracil phosphoribosyltransferase homolog.
- Pogo transposable element derived with KRAB domain
Sequence:
MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEETVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGLSKRQTNGYLNGYTPSRKRQASESSSRPH
Protein: Earmuff, isoform D (A0A0R4YI50)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVYFSPRGMQPCSPAGEIAMMPPSKSPVMESAASEQNPAQQSQQQDEQSAKRACPLKFSIAKIMEPDHRPSQVPPPQPAPVSFATNDDDEDEDPEIDADSERSCSPIEVISLDQSPSTVNYDSAFKKYVPGPCSGATSSVASPPSTAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHPLAAAAAVAAVAQSQAVPNLQHTLEKSPVAQRTAQSSGLQANLKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGSIEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHEIGGDLDDLDMPPTYDRRREYTRREPLASGYGQASGQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPRSAVSQYPPGGFHHQLGVAPPHDYPSGSAFLQLQPQQPHPQSQQHHQQQQRLSETFIAKVFXQRYYAESLNSSTGSTSTTSSTVTTTTTAISSMATSRSDLLIDXLQFVAAAAAASSSNSGQDTGESPSPELGCTALGSAVRALNGLF
Protein: Homeobox protein Hox-A3 (Homeobox protein Hox-1E) (O43365)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-A7
- Homeobox protein Hox-A4
- Homeobox protein Hox-A5
- Pre-B-cell leukemia transcription factor 1
- Homeobox protein Hox-A9
- Homeobox protein Hox-A10
- Homeobox protein Hox-A2
- Homeobox protein Hox-A6
Sequence:
MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL
Protein: Transmembrane protein PMIS2 (Protein missing in infertile spermatozoa 2) (Q8CES1)
Organism: Mus musculus (Mouse)
Function: May play a role in spermatozoa mobility.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDTDEQGAPGRKPLDRPQTPDELKFYARNYVMLALLAMILFLPFGILAIYFSIQTNEANKCSNWEDAYRNSSRTMWFNMLAIVAFVGIIYILVLVL
Protein: HSPB1-associated protein 1 (27 kDa heat shock protein-associated protein 1) (Protein associated with small stress protein 1) (Q96EW2)
Organism: Homo sapiens (Human)
Function: May play a role in cellular stress response.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Heat shock protein beta-1
- Heat shock protein beta-2
- Heat shock protein beta-3
- Solute carrier family 49 member 4
- 2-oxoglutarate and iron-dependent oxygenase JMJD4
Sequence:
MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAKYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQLLIQGRSL
Protein: Leucine-zipper-like transcriptional regulator 1 homolog (Q9V410)
Organism: Drosophila melanogaster (Fruit fly)
Function: Inhibitor of Ras signaling. Acts as a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (By similarity). Together with Nf1, plays an important role for normal sleep behavior, mainly during the night. Might affect sleep by modulating GABA signaling in Rdl-expressing neurons. Might play a role in the regulation of brain glycogen metabolism and organismal levels of triglycerides.
Interaction partners:
- Regulatory protein zeste
- Synaptic plasticity regulator PANTS
Sequence:
MLKSISGGVGVASTERGGGGGGCGGGGAGGSASGSRSTSGSGRASCGLGSSSISSGLSAVCGFVTGASGGGGFERDRDRDRGLANISGGSTPAGILYCPACMAAANQQSPSQNSSPHHESFFLRSSFKSSKRNKARKSASTAGCLDAQHIRANLRMSMSSSMRSSRGNGGGGAASSSHPPGSSCSSGPGGSGCSMAYDAASNASSGSGSGSGKATSPGSYSCNALNVDFTSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFQSAMWVEWKFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENQWEEVDQLGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSVIQPEQNSDVPSGRVFHASAVICDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFQDKQFCDIQFIVGAEEIRILAHIAFVAARSKYLRNKILAAREARQQQMEKVYGVGQVDALALNAGAGGDRGPMLEVRLANASPEAFEIILNYIYTDRIDLKDTYSKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKLNVLEALYNADKSNIKIIKDHCMQFIIKEENFTDVVMSSEFSDLDKPLLVEIIRKRLYPSKLVIDTSYEGNIGTTLEIDLCAFLESTGKDFCDISLVLEDHVIPAHKSVLSSRCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKMPPQDALYLFQAPCFYGLANNRLHAFCKYSLEHNITFENVLQTLEASDITKIYDIKEYALKLIVKDFAKVARLPKIAGLSRELLLEIIRAVADSHGEFLTRININTDI
Protein: Kinetochore-binding protein 3 (O45406)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus. Chromosome, centromere, kinetochore. Chromosome. Note=Associated with kinetochores. Localize to kinetochores throughout mitosis. Begin to localize to chromosomes during prophase and persist on chromosomes until the end of mitosis.
Interaction partners:
- KNL
- Kinetochore protein Nuf2 homolog
- Kinetochore protein ndc-80
- CNH domain-containing protein
- SET domain-containing protein
- Protein zwilch homolog
Sequence:
MESLNEYMDKIINRLKAVNEKDELVDEGMRKLQKCQEKIMKTRIDAQKHIDERHEQQSFEQQLLNKNMFETEQLEEKLKRLDDENKIGNEREFNKKLEAISAKWTDDVNLLKTTPNEPNDGNRKKLSNLSNILV
Protein: Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1) (Q9UHD8)
Organism: Homo sapiens (Human)
Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17546647, ECO:0000269|PubMed:17922164}. Note=In an epithelial cell line, concentrates at cell-cell contact areas. After TGF-beta1 treatment and induction of epithelial to mesenchymal transition, colocalizes partly with actin stress fibers. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.
Interaction partners:
- Septin-7
- Septin-6
- Septin-2
- Septin-11
- Uncharacterized protein C17orf47
- Septin-1
- Septin-10
- Neuronal-specific septin-3
- Septin-5
- Septin-12
Sequence:
MKKSYSGGTRTSSGRLRRLGDSSGPALKRSFEVEEVETPNSTPPRRVQTPLLRATVASSTQKFQDLGVKNSEPSARHVDSLSQRSPKASLRRVELSGPKAAEPVSRRTELSIDISSKQVENAGAIGPSRFGLKRAEVLGHKTPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGMEEKEPEAPEM
Protein: BetaH spectrin (Q99140)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
LQTPTPSNRNSANMTQRDGIIKFENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEKLGKPNSGRMRVHKIENVNKSLAFLHTKVRLESIGAEDIVDGNPRLILGLIWTIILRFQIQEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHRPDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYYHTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGWAEKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKS
Protein: Protein p13 MTCP-1 (p13MTCP1) (Mature T-cell proliferation-1 type B1) (MTCP-1 type B1) (Q60945)
Organism: Mus musculus (Mouse)
Function: Enhances the phosphorylation and activation of AKT1 and AKT2.
Interaction partners:
- RAC-alpha serine/threonine-protein kinase
- RAC-gamma serine/threonine-protein kinase
- RAC-beta serine/threonine-protein kinase
- T-cell leukemia/lymphoma protein 1A
- Protein TCL1B2
- Protein TCL1B4
- Protein TCL1B1
Sequence:
MAREDVGAPPDHLWVHQEGVYRDEYQRTWVAVVEEETSFLKARVQQVQVPLGDATKPSHLLTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD
Protein: Probable ubiquitin conjugation factor E4 (EC 2.3.2.27) (Plant U-box protein 1) (RING-type E3 ubiquitin transferase E4) (U-box domain-containing protein 1) (Ubiquitin-fusion degradation protein 2-like) (UB fusion protein 2-like) (Q9LF41)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ubiquitin-protein ligase that may function as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chain assembly on substrates monoubiquitinated by another E3 ubiquitin ligase.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P54860}. Nucleus {ECO:0000250|UniProtKB:P54860}.
Interaction partners:
- OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 2
- E3 ubiquitin-protein ligase UPL3
- AT2G21270 protein
- Cell division control protein 48 homolog A
- E3 ubiquitin-protein ligase UPL4
- Ubiquitin domain-containing protein DSK2b
- Probable ubiquitin receptor RAD23a
- Ubiquitin receptor RAD23d
- Ubiquitin receptor RAD23c
- Ubiquitin receptor RAD23b
Sequence:
MATSKPQRSPAEIEDIILRKIFYVTLTESTDSDPRIVYLEMTAAEILSEGKELLLSRDLMERVLIDRLSGDFSDAEPPFPYLIGCHRRAYDESKKIQSMKDKNLRSEMEIVTKQAKKLAVSYCRIHLGNPDMFGNSDKPSGGLDNRLKKRNVSPVLPLIFAEVGSGSLDMFGASSSGVQAPPGFLDEFFKDSDFDSLDSILKELYEDLRSTVINVSVLGDFQPPLRALKYLVSLPVGAKSLVSHEWWVPRGAYMNGRAMELTSILGPFFHISALPDNTLFKSQPDVGQQCFSEASERRPADLLSSFSTIKNFMNILYSGLHDVLMILLKSTDTRERVLQFLAEVINANASRAHIQVDPVSCASSGMFVNLSAVMLRLCEPFLDPHLTKRDKIDPKYAFCGHRLKLSDLTALHASSEEVTEWIGKDAMANANDAGRENGNESRLLQSKEATSSSSNASGQNAKSATKYTFICECFFMTARVLNLGLLKALSDFKHLAQDISRGEDNLATLKAMRDQAPSPQLELDISRMEKELELSSQEKLCHEAQILRDGDFIQRALSFYRLMVVWLVGLVGGFKMPLPSTCPMEFSCMPEHFVEDAMELLIFASRIPKALDGVPLDDFMNFIIMFMASPEYVRNPYLRAKMVEVLNCWMPRSSSSSSATSTLFEGHQLSLEYLVRNLLKLYVDIEFTGSHTQFYDKFNIRHNIAELLEYLWQVPSHRNAWRRIAKDEEKGVYLNFLNFLVNDSIYLLDESLNKILEIKQIEADMSNTAEWEQRPTQERQERTRLFHSQENIVRIDMKLANEDVTMLAFTSEEITAPFLLPEMVERVANMLNYFLLQLVGPQRKSLSLKDPEKYEFRPKQLLKQIVRIYVNLARGDTVNIFPGAISSDGRSYNEQLFNAGADVLRRIGEEGRIIQEFMELGTKAKAAASEALDAEAALGEIPDEFLDPIQYTLMRDPVILPSSRITVDRPIIQRHLLSDNHDPFNRAHLTSDMLIPDIELKAKIDEFVKSHQSKKRTSGEDSSNKERIQTTNSDMLID
Protein: V-set and transmembrane domain-containing protein 2A (Q8R0A6)
Organism: Mus musculus (Mouse)
Function: Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway.
Subcellular location: Secreted {ECO:0000269|PubMed:28052263}. Note=Secreted by adipose precursor cells (PubMed:28052263). Not detected in the nucleus (By similarity). {ECO:0000250|UniProtKB:Q8TAG5, ECO:0000269|PubMed:28052263}.
Interaction partners:
Sequence:
MMGIFLASVGFMFFSVLYVQQGLSSQAKFTELPRNVTATEGQNVEMSCAFQSGSASVYLEIQWWFLRGPEDLEQGTEAAGSQVELLPDRDPDNDGTKISTVKVQGNDISHKLQISKVRKKDEGLYECRVTDANYGELQEHKAQAYLKVNANSHARRMQAFEASPMWLQDTKPRKNASSVVPSSVHNSANQRMHSTSSPQAVAKIPKQSPQSGARIATSHGLSVLLLVCGFVKGALL
Protein: Traffic jam (Q7JS61)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEDPTINDTYVQEFDLHHLEVGGNGAGQSHGAGAASQVTTLGHVKREDHSPPQPVAVKWTTIHGDPTNPDDDPDSLPLSGPEPAGAVEVSPSPHIKLRSFSGHHQWHMDERRLQPLSPPPEQYGPLPGQAILVNTSSGAGVPGGVPSTPPETPPVVGSPTGSSSCPAQTYAHHYARTPGSSVSVSASAAAAAAASAGAASVSAGLSHDMMWLTNSIRADQQPLDLRPLPYPGSQEEAEEWDRQRDYALQAAAAHHHHHGQPLMQAQHHPHGHGGHPHQVMLQQSKYPHHHHHHFHNLELTPINMHSNSYGSASGALTPTCLPQVPSNGSGSSGGGGGSGSGSGGPGSVGGGSCVITRAALQPCRPLSASSTRSSNNMSPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVRLKQKRRTLKNRGYAQNCRSKRLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDALMQRLQRAANGGVGAGGATAGGDSQSSPEFYL
Protein: Beta-galactosidase related protein (Q9M0G1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MICVPGPIIEALSSTTLSGAGEASVHRHRDPNFSSFRRYFVTLVSFFIFPLLKLFPILSPLVIPLVIPAHNLLTNLPHLASLPGRSSTQIKEGRLKQHALSFSHSSAAALWTDSCSELSHVEKDATPWIFATYLSHGHSLLPTIFHSSEMTPALQIISPFLDSRRSTSAFWHLDMKLGFSPVDLVSFAGPFLPFRPKPICCFRTCKAFILRSDFFNSMLGPLIFLCRSPLINGHGHHLIEISPWRFWFFIYHLRILVLAISRNVWPHSKVLKTFSLIFLNCTCLCVKCGFELWVFIAQWSPSSSSIAFKLITMSIIMFHCLIVYAAIDRRFVCLLCWILKLTLTDYRTIVLRILAILFPWVLQLAPVRSIASMSLSTSLRPLTVTNLLSFDYFEDDPSIYCDLTCCTVLLCLCLKALMEFKSMHFIFLFMVLGNTVCCNALIFEFLNSISCNCSMFH
Protein: Protein EGO2 (Q3E830)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Protein MEH1
- Protein SLM4
- GTP-binding protein GTR1
- GTP-binding protein GTR2
- Protein LTV1
- Protein LST7
- Target of rapamycin complex 1 subunit TCO89
- Translation initiation factor eIF2B subunit gamma
- Translation initiation factor eIF2B subunit beta
- Guanine nucleotide exchange factor subunit RGP1
Sequence:
MEAEKQSDIKGTIAFDTHGNVIESTGVGSQRIEDIGDLSKVTLDAEGFAQVQGDSLLVHLYKRNDITLAVYTSAQ