wanglab/gogpt-training-data huggingface dataset:
Protein: Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (Q90978)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MWATQLLPALLLHQLLLPPITIPAAEGKGKRRNPLHDYKKTGELMLIKVNKTLEVKTKLLNTTEQCAKRCSRNKGLSFTCKAFAYDRVTKRCHWLSFNSLTNGVRKKQDHAFDLFEKKDYVRNCIIGKGAEYKGTISITKSGIQCQAWNSMIPHEHSFLPSSYRGKDLRENYCRNPRGEEGGPWCFTTSPQMRHEVCDIPLCSEVECMTCNGESYRGPMDHTESGKECQRWDLQRPHKHKFRPERYPDKGFDDNYCRNPDGKLRPWCYTLDPNTPWEFCAIKTCDVGILNSTEAVAETTTCIQGQGEGYRGTVNTIWSGIQCQRWDSQFPHQHNITPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRIGYCSQIPKCDVSNEQDCYRGNGKSYMGNLSNTRIGLTCSTWDKNIEDLRRHIQIFREPDVSKLKKNYCRNPDDDFHGPWCYTDDPLIPWDYCPISRCTGDTTPTTTSLDDTVIPCASTKHLRVVNGIPTQTNEGWVVSLTYRNKHICGGTLVKEEWVLTARQCFPSRYKDLKDYKAWLGVHNIKGKGEEKHRQVRNISQLIYGPAGSDLVLLKLSRPAILTNFVEIIRLPISGCTIPEKTSCSVFGWGYTGLPNYDGLLRVANLFILGNEKCNQYLKGKITVNESEICAVAETIGAGPCERDYGGPLVCEQNRLKIVVGVIVPGRGCAIRNRPGIFVRVSYYSRWIHKIMMTYRKP
Protein: RING finger protein 112 (EC 2.3.2.27) (Brain finger protein) (Neurolastin) (Zinc finger protein 179) (Q96DY5)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density.
Subcellular location: Membrane {ECO:0000269|PubMed:26212327}; Multi-pass membrane protein {ECO:0000255}. Membrane {ECO:0000269|PubMed:26212327}; Peripheral membrane protein {ECO:0000269|PubMed:26212327}. Cytoplasm {ECO:0000269|PubMed:24359566, ECO:0000269|PubMed:27918959, ECO:0000269|PubMed:9806830}. Nucleus {ECO:0000269|PubMed:24359566, ECO:0000269|PubMed:26951452, ECO:0000269|PubMed:27918959, ECO:0000269|PubMed:9806830}. Nucleus, nuclear body {ECO:0000269|PubMed:24359566}. Nucleus, nucleoplasm {ECO:0000269|PubMed:24359566}. Endosome {ECO:0000269|PubMed:26212327}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000269|PubMed:26212327}. Postsynaptic density {ECO:0000269|PubMed:26212327}. Perikaryon {ECO:0000269|PubMed:26951452}. Cell projection, neuron projection {ECO:0000269|PubMed:26951452}. Note=Predominantly in the nucleus, but some amounts were also found in the cytoplasm (PubMed:24359566, PubMed:9806830). Oxidative stress stimulates its shuttling from the cytoplasm into the nucleus (PubMed:27918959). Recruited to nuclear bodies via its interaction with ZBTB16 (PubMed:24359566). Localizes to the cell soma and neuritis and only slightly to the nucleus in the neurons of most brain areas (PubMed:26951452). {ECO:0000269|PubMed:24359566, ECO:0000269|PubMed:26951452, ECO:0000269|PubMed:27918959, ECO:0000269|PubMed:9806830}.
Interaction partners:
- High affinity 3',5'-cyclic-AMP phosphodiesterase 7A
Sequence:
MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWVLPREEAQGWMGQAVQGGTRTSRSHASFPKLELGLGHRPSPTREPPTCSICLERLREPISLDCGHDFCIRCFSTHRIPGCELPCCPECRKICKQRKGLRSLGERMKLLPQRPLPPALQETCAVRAERLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLDHLLSGLPSLESGDSGRPRAEGSLPGIRWGANGLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSKETRVKLCALTMMLSSYQILNTSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNKSGQGHVGDILQKLSGKYPKVQELLLGKRARCYLLPAPERQWVNKDQASPRGNTEDDFSHHFRAYILDVLSTAPQHAKSRCQGYWSEGRAVARGDRRLLTGQQLAQEIKNLSGWMGKTGPSFNSPDEMAAQLHDLRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKEREQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDREPLLQEE
Protein: Tryptophan aminotransferase-related protein 2 (OsTAR2) (EC 2.6.1.27) (Protein FISH BONE) (Q5VQG8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable tryptophan aminotransferase involved in auxin (IAA) biosynthesis. Required for auxin production to initiate multiple change in growth in response to environmental and developmental cues. Functions upstream of YUCCA1 in auxin biosynthesis. Required for polar auxin transport.
Interaction partners:
- Indole-3-pyruvate monooxygenase YUCCA1
- indole-3-pyruvate monooxygenase
- Flavin-containing monooxygenase
- Indole-3-pyruvate monooxygenase YUCCA8
- Os01g0178000 protein.
- Tryptophan decarboxylase 2
- indole-3-pyruvate monooxygenase
- indole-3-pyruvate monooxygenase
- Os10g0400500 protein
- Tryptophan aminotransferase-related protein 1
Sequence:
MAALRVGTRAVEGRFQASNGGGGGGGGMAPSSRLVAAHREAKPRSSHSAAPWKLPRRRAGAMPLWRVAVFASVALNVATLALLLHHYATSPPPHHHHHDAGLATRSSDAAVHRRARTASSMAPSTGKPAVTTDSVINLDHGDPTMFEEFWRETGDAAEVVIPGWQTMSYFSDVTNVCWFLEPELDRQVRRLHRVVGNAAVDGYHVLVGTGSTQLFMAALYALAPDAAAAAAGEPISVVSTAPYYSSYPAVTDFLRSGLFRWAGDADAFKGDSYIELVCSPNNPDGAIREAVLDPKTGNGRTVHDLAYYWPQYTPITKRASHDIMLFTVSKSTGHAGTRIGWALVKDRAIARKMTKFVELNTIGVSKDSQMRAAKVLAAVSDGYERRPEQTKETMTTPLRLFDFGRRKMVERWSMLRAAAAASGIFSLPEETSGFCNFTKETAATNPAFAWLRCDREDVEDCAGFLRGHKILTRSGAQFGADARYVRVSMLDRDDAFDIFINRLSSLK
Protein: Poly(A) RNA polymerase, mitochondrial (PAP) (EC 2.7.7.19) (PAP-associated domain-containing protein 1) (Polynucleotide adenylyltransferase) (Terminal uridylyltransferase 1) (TUTase 1) (mtPAP) (Q9NVV4)
Organism: Homo sapiens (Human)
Function: Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18172165}. Mitochondrion {ECO:0000269|PubMed:15547249, ECO:0000269|PubMed:15769737}.
Interaction partners:
- Poly
- Poly
- Poly
- ATP-dependent RNA helicase SUPV3L1, mitochondrial
- Calcium-binding and coiled-coil domain-containing protein 2
- Terminal nucleotidyltransferase 4B
- G-rich sequence factor 1
- SRA stem-loop-interacting RNA-binding protein
- Polyribonucleotide nucleotidyltransferase 1, mitochondrial
- Leucine-rich PPR motif-containing protein, mitochondrial
Sequence:
MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT
Protein: Ena21p (Q5A5B0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MILVLIISMIIALAIKDWISGGVIAGVILINVVIGFVQELKAEKTMGSLRNLSSPTARVTRNGDDLTIPAEEVVPGDIVHVRVGDTVPADIRLFDCMNLETDEALLTGESLPVAKNFQIVYDDFSVPIPVGDRLNLIYSSSIVSKGRGSGIAIGTGLNTEIGSIAKSLQGDSGLIRKVDKSNGRQPQKREYFHAGLGSIYDIVGNILGVTTGTPLQKRLSWLAILLFWVAVVFAIVVMASQKFHVNKEVAIYAICVALSMIPSSLIVVLTITMAVGAQVMVTKNVIVRKLDALEALGGIDNICSDKTGTLTQGKMIAKKVWLPNVGTLDVQNSNEPYNPTIGDVRYSPFSPKFIKDTDEEIDFNKPYPDPMPESMHKWLMTATLANIATVNETKDEETGELVWKAHGDATEIAIQVFTTRLNYGRESIAQDYEHLAEFPFDSSIKRMSAIYKKDGETKVYTKGAVERVLELCDYWYGERTDDNFDSQTLVKLTEADIKLIEENMVALSSQGLRVLAFATKDLGDADISNREQVESHLIFQGLIGIYDPPREETAPSVKLCHRAGINVHMLTGDHPGTAKAIAQEVGILPRNLYHYSEDVVKAMTMTANEFDALSDEEIDKLPVLPLVIARCAPKTKVRMIDALHRRKKFAAMTGDGVNDSPSLKKADVGIAMGLNGSDVAKDASDIVLTDDNFASILNAIEEGRRMSSNIQKFVLQLLAENVAQALYLMIGLAFIDASGYSVFPLSPVEVLFVIVITSTFPAIGLGFCGADDDILEKPPSSTIFTWEVIIDMFGYGFIMAVSCLLCFVIIVYGAGDGDLGVNCNSIDANTDTCSLVFKGRSAAFSVMTWCALVLSLECLHPRTSVFRFPTQDLWANQFLLWSILGGIVSVFPVIYIPVINTKVFLHKSITWEWGVAIGCTLLFLLGAELWKWGKRIISRTAKASNPEYELERNDPFQKYASFSKSNTMVVV
Protein: LD42868p (Q9W4F8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- LD27564p
- AT25567p
- Heparan-alpha-glucosaminide N-acetyltransferase, isoform A
Sequence:
MGTRERERECRLCAVTFFAKLHPGDVCGSNGLPLTPNSIAILGRAQKLKELQDEHLCQYLDVIRGKHERTIVVSEYLGLSLEDYAMRHPPLAIAQILRIFYQVACGINVLSRHHLVAHNVEPKHILLSSDGQRVKLFNYGLHHMTKGGAYVPFPIGNIRYMAPERLLGLNGNVKSDVWSLALVMVELILQIELWPKLKLSNVVRKILAFGKSNGALEKIAREHQCHERYVQMDQRLRQLLESCLSVLPKRRPLPGELLEHPIFEEVLLDLKKQKMQPLSPETEHLPLLLRCPLSQIYHLWQLAGGDVQAELKKEGLIRSEAPILGLPQIVRLSGASVCPGRSQAQLMDDRVVPLRLKALLQRLSGLPAAVYFPLLHSPRFPAHFARELQELPLVIREKDIEYQFQRVRLFARLLQGYPHTAEQLQREAAVDVPPLLRGPIWAALLEVVPNGSYAKIDKFTSTSTDRQIEVDIPRCHQYDELLSSPDGHRKLRRLLKAWVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQWFFLKDNSAVIKEYLSKFSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLWDKLMLGDSSYPLFIGIAILRQLRSTLLTSGFNECILLFSDLPDIVMDGCVLESQKMYEATPKSITHRQHALRLQPPQALDIGVADVELKHLQQEQCPRISAKDVQFLLDNSPAELALIDLRSVVEFGRVHVPHSINIPFATVQLGEQRLEALQVPQLEAQLRGKIVVCVSNIHQHSVEFSHFLVACGVQRTCILHKGFNVLHSIEPNILISN
Protein: Metal tolerance protein 10 (AtMTP10) (Q0WU02)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Tonoplast.
Interaction partners:
- Metal tolerance protein 12
- Metal tolerance protein C2
- Metal tolerance protein B
- Metal tolerance protein A1
- Metal tolerance protein A2
- Metal tolerance protein C4
- Metal tolerance protein 1
- At4g01860
- Membrane lipoprotein
- Organic cation/carnitine transporter 6
Sequence:
MPLNSYIFFLFLTTSPRNTFFGIRTHSDRIMATEHITRTGDEYNVELLPSDDDAPPLESSWRLNLDAFQLPSSTGGRHDGRTRFSRYFRTPRKERRVSEYYKKQERLLEGFNEMETIHENGFASGVPTEEEMKKLAKSERLAVHISNATNLVLFVAKVYASMESRSMAVIASTLDSLLDLLSGFILWFTANAMRKPNQFHYPIGKRRMQPVGIIVFASVMATLGLQVLLESGRQLVAKSGIHMNSTEEKWMIGIMVSVTIVKFLLMLYCRGFQNEIVRAYAQDHLFDVVTNSIGLATAVLAVKFYWWIDPTGAILIALYTIATWARTVLENVHSLIGRSAPPDFLAKLTFLIWNHHEQIKHIDTVRAYTFGSHYFVEVDIVLPEDMRLQEAHNIGETLQEKLEQLAEVERAFVHIDFEFTHRPEHKCN
Protein: Neurofilament light protein (Q8L4Q6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Gelsolin protein
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- 26S proteasome non-ATPase regulatory subunit 1 homolog A
- Small ribosomal subunit protein eS1y
- Small ribosomal subunit protein eS1z
- Small ribosomal subunit protein eS10x
- Small ribosomal subunit protein eS10y
- Small ribosomal subunit protein eS10z
- Small ribosomal subunit protein eS12z
- Small ribosomal subunit protein eS12y
Sequence:
MDGGDDMDSLFEGMELFTPASQFSGDSKVSSPPQSEETKAAEATLITAPSQPDVTEATLITATSQPDITEALDENLFSDLTIVTPVQHQPEPMEAVITTHQSPAKNYGRQVSRRKKRAAGLRIGYGRHETNNLDEDEDDAVSQQSDSVSQVSDSVSQISDSVAQVFDSGNQSLDSPVVTVVVGNGSSRLELVKAQIEAKLNRSRDLAASVTSARKNAIRKKRQASENLRLASTTHEELEKQLEEAIETEDFDAAERISESLAAKERDRLALLALLRQAESDCDAIESKMEEVLLSQIAAEEESACLLRSFGTDAENDAGSILEKAEAFYSDEMEKWHSCSEDVEVRKVELDIESVVVDNVRLSLNGILEGSVEQDMKEKEILQKKKEHLANELEELLALVKAKEKEIDENDSQIEAVEERINNVVTGFKELQTSMDKMLNDVQAGLTEVDKETEDLSRKKKDVDEFMTSEKERGAKLRDLARVSADEACEYEEVIKLRKGLMSYVSKTREERAKLVNIEEKLSEEVQKLQEEVSSTRELLKERSSKKSIIQQNITSFMDKIMFIEKRMPELEAEKKVAASTRNFKEAGRIAAEAKSLNLEKDKTQMETGKANAELEKAEHEIEETIKRLQEIEKLILSKEKELAISRFQRLRIDSGTAKAERSAALELSDLEEANLLLEEAQEAESEAEKLKLTGGLKEEEEEEEKAKSNEVFVSMELIATVGLKKLQELVESVPS
Protein: GM10839p (Q8T9I5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRKHHKKLKKVKEGKNKKKKEKKDKSKKADQIGLPSFKSDRKIKANDKRQKKEKKKDKDKQILVHIPDDTEEFDKVPLANNDEPVLKSSSMTINPSLGAATSGISPNQIPKLTLKLSGKSTLFSSSEKEMTDAGKLKQTTILSSENKKRERDNSPELARFSPLVTGPPKNKQSETLHLGNSSTAVLPVPSPVAVRAVQLPVSQTSSNSAGWLSNPNNSNTASSTLSASSVLLPQQLMLAPHTIMNNFVPAMCNSTGTVSKSGLCSSPPNTSEENANAMQIAESSRPSSYVDAEGNRIWICPACGKVDDGSAMIGCDGCDAWYHWICVGITFAPKDNDDWFCRVCVTKKRIHGSEKKKRRNKKK
Protein: Sugar transport protein 7 (Hexose transporter 7) (O04249)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15060130}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Phenylcoumaran benzylic ether reductase 1
- Sucrose transport protein SUC2
Sequence:
MAGGSFGPTGVAKERAEQYQGKVTSYVIIACLVAAIGGSIFGYDIGISGGVTSMDEFLEEFFHTVYEKKKQAHESNYCKYDNQGLAAFTSSLYLAGLVSTLVASPITRNYGRRASIVCGGISFLIGSGLNAGAVNLAMLLAGRIMLGVGIGFGNQAVPLYLSEVAPTHLRGGLNMMFQLATTIGIFTANMVNYGTQQLKPWGWRLSLGLAAFPALLMTLGGYFLPETPNSLVERGLTERGRRVLVKLRGTENVNAELQDMVDASELANSIKHPFRNILQKRHRPQLVMAICMPMFQILTGINSILFYAPVLFQTMGFGGNASLYSSALTGAVLVLSTFISIGLVDRLGRRALLITGGIQMIICQVIVAVILGVKFGDNQELSKGYSVIVVIFICLFVVAFGWSWGPLGWTIPSEIFPLETRSAGQSITVAVNLLFTFIIAQAFLGLLCAFKFGIFLFFAGWVTVMTIFVYFLLPETKGVPIEEMTLLWSKHWFWKKVLPDATNLEDESKNVSV
Protein: Histone H4 (P62799)
Organism: Xenopus laevis (African clawed frog)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
Sequence:
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Protein: Myb family transcription factor RLI1 (Protein HIGHLY INDUCED BY NITRATE GENE 1) (Protein REGULATOR OF LEAF INCLINATION 1) (Q0J995)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor binding to specific DNA sequences of target genes promoters, such as the motif R1BS 5'-NAKATNCN-3' and the motif P1BS 5'-GNATATNC-3' to trigger their expression. Nitrate-induced component involved in modulating phosphate (Pi) response and homeostasis together with PHR2; activates directly the expression of Pi starvation-induced (PSI) genes upon nitrate disponibility, thus triggering the nitrate-induced phosphate response (NIPR) promoting Pi uptake activity.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:33316467}.
Interaction partners:
- Os01g0314700 protein
- Kinesin-like protein KIN-14I
Sequence:
MLQDIMNTKKIKLHDCHFGSPLCDPSPAPHLLSSAAAAGLSFHPGLVSSAAQHQQHGAGGWLHEEYYAPRSSPPSSLLAQTCVGSNATAFYAAENLPQFDFPALGTAAAAAAKAPFRSSESELYRPVDPLLLRADHSVRTYYVRPQKRDSGERTPLPPPSQQQHQDRIHGLFAGAPTTRLLSGEPKIHSFPPQVAAKPILPAMDAPSLQNQMENQLTRNCIGAATPVTPTGNLAGSGAPSKTRIRWTQDLHERFVDCVNQLGGADKATPKGILKLMNSDGLTIYHIKSHLQKYRIAKYMPASSEGKQLEKRATGNDMQNLDPKTGMQITEALRVQLDVQRRLHEQLEIQRNLQLRIEEQGKRLQKMFEDQLKASRSVMEPQELDDVVAFAAGDGDDDAFDDVDVQLLAVAGSGYDDAGFQSKIS
Protein: Inner membrane protein YhjD (P37642)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Probable phospholipid transport protein YdbH
Sequence:
MTQENEIKRPIQDLEHEPIKPLDNSEKGSKVSQALETVTTTAEKVQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPMLLQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAIRAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALHLNSIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVIKIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGKTQP
Protein: UPF0653 protein C607.02c (Q9US15)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized protein new13
- DNA-directed RNA polymerase I subunit rpa34
- Signal peptidase complex subunit 1
Sequence:
MPTKTKKRSVLEAERKKIGLDHAPKEDESVDDNFPKQFKRLLQQKEYHESKKKEIKKGNLKNKKKKDYGKIQRLPGERLSEFSQRVNKAIPVSFKSGPSKIDEFTDKKEKKKIAKRKEKRERDWNEIEENFEDKTWEADTTGQFIQIESRKKRKNSPDPWANLQTKPSFGETVQAPPELPELKIKETKYLENVPKVNNMGQTESMARRQALGKQRLELIEKYRELMKTKRK
Protein: Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) (Q9VCA5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Probable phenylalanine--tRNA ligase, mitochondrial
- Phenylalanine--tRNA ligase alpha subunit
- Tyrosine--tRNA ligase
- Bifunctional glutamate/proline--tRNA ligase
- leucine--tRNA ligase
- leucine--tRNA ligase
- Probable elongation factor 1-beta
- Lysine--tRNA ligase
- Probable elongation factor 1-delta
- Isoleucine--tRNA ligase, cytoplasmic
Sequence:
MPTIGVKRDLLFEALGKTYTDDEFQDLCFAFGLELDEVTTEKQMLTKEQGDVAAAANASEEIIYRIDIPANRYDLLCLEGLVTGLLVFQGKLKPPKFQFVELAKRQVLKIDPSTAQIRPYAVAAVLRNVTFTQASYNSFIDLQDKLHQNICRKRTLVAIGTHDLDTLQGPFSYEALAPDQIKFKPLNQTKEMTGSELMDFYSTHAQLKQYLPIIRESPVYPVIYDANRVVLSLPPIINGDHSKITLKTKNVFIECTATDRTKAKVVLDTIVCLFSEHCAQKFTVEPCDVVQPDGSVISYPELEVREERISVKRANAYIGIDEPAEKLADMLTRMYLEAKVDGDSLVVKIPPTRHDVIHACDIYEDVAIAYGYNNIKKSLPAFMQIAKQFPLNKLTEQLREQVAQAGFTEALTFTLCSRDDIGRKLNKNIDALPAVHIGNPKTLEFQVVRTTLLPGLLKTLVANRKMPLPLKLFEISDVVVADESTEVGARNERRVCAVNCNKTAGFEVVHGLLDRVMQLLSVPWKSASGTKGYYLQATEDPSYFPGRCANVMYDGVVIGKIGVLHPTVLQAFELTTPCSAVEFTIEPFV
Protein: Ubiquinone biosynthesis accessory factor UbiJ (P0ADP7)
Organism: Escherichia coli (strain K12)
Function: Required for ubiquinone (coenzyme Q) biosynthesis under aerobic conditions. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02215, ECO:0000269|PubMed:30686758}.
Interaction partners:
- Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
- Ubiquinone biosynthesis accessory factor UbiK
- 2-octaprenylphenol hydroxylase
- 2-octaprenyl-6-methoxyphenol hydroxylase
- 3-demethoxyubiquinol 3-hydroxylase
- Ubiquinone biosynthesis O-methyltransferase
- Probable protein kinase UbiB
- 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
- Sec-independent protein translocase protein TatB
- 4-hydroxybenzoate octaprenyltransferase
Sequence:
MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGFSTSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLTALIRSGELEVQGDIQVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEAITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK
Protein: Spindle pole body component (Q5BEM5)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000256|RuleBase:RU363050}.
Interaction partners:
- Spindle pole body component
- Spindle pole body component
- Gamma-tubulin complex protein 3
- Spindle pole body component
- Mitotic-spindle organizing protein 1
- Tubulin gamma chain
- DASH complex subunit DAD2
- DASH complex subunit DAD3
- DASH complex subunit SPC19
- DASH complex subunit DAM1
Sequence:
MDYQDYGADPFSSDGLWRISKFTLDSLQPLESLPWDEKLPDISEGFFKTPFHLLEKEDTELHKLDIFGADLFEPSVFAESTTDASSEGQQETNARAQDIGNEFDNIWKIETIDSLQHNNAPRSWERYHDRQFKEPASAYFSESGATGFDAAIELHSKPEDAGYSKRTVRNDVFFQSLFRVGLGWSSMLFRFNKQRQKFEKVVKDIRISGVSTLALSGIIDEMLQCGNNMQRVRTFIGRVPTAAAEPSALSAFSTAASVIVYTLEKQLLHSFKQISSVLQIRALFQRCAELIGVLVNMMDAVETAGSEARIISSVFKLAAHYAQIYGQMESLFREIVFKVAQPWLTYVETWIGFRPETSASIELLTNGRSFVSLEKSESNGKISSQERHEYAYLPEQMPSFVPPDQAYLIYESGRSLRLLKRYHPHHPLAGEQVRIDSPKLACAGTWAELERIQMKARDYEARLRAEVLKYNRNGPSEHVMNIEKPNTIESKELPDAFSLFDINDAQHMTGLLASDASLEKAKLGQLLNEADHDIEKQSGKLETNFAPEVTSSLYLSLAPLLSSQALLIDFSCLHLLFKEHNLKDHLLLQWRFQLLGDGYFMSRLSQSLFDPEMESGERKIGVVRSGVHTGLRLGSRDTWPPASSELRLVLMGILNECYSGEYADGSGNPEFEKEKELPGGLSFSIRELTEAEIAKCKNPNAIEALDFLCLQYKPSNVLEVIITQRSLRKYDQLFKQLLRLLRMVSVVKGLIRDSTARNSLSGDTHNLLQKFRIDSQHFILALSDYFFHLAVGSTWQRFRDTLSQIEACLDRGDIDATIEAAHSIPTLRAYHENTLDQMLFALFLTKRQAEVARLLEGIFDTILRFAPLSRKDGTHGVRHESEAMVKRLYAVFRKQMAAFVGYLRSLDGARGAVASSSKALGTGRAGMAFAARGGSANVFDHLLVRLDMKRYY
Protein: CD160 antigen (Natural killer cell receptor BY55) (CD antigen CD160) [Cleaved into: CD160 antigen, soluble form] (O88875)
Organism: Mus musculus (Mouse)
Function: Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells (By similarity). Receptor for both classical and non-classical MHC class I molecules. Receptor or ligand for TNF superfamily member TNFRSF14, participating in bidirectional cell-cell contact signaling between antigen presenting cells and lymphocytes. Upon ligation of TNFRSF14, provides stimulatory signal to NK cells enhancing IFNG production and anti-tumor immune response. On activated CD4+ T cells, interacts with TNFRSF14 and down-regulates CD28 costimulatory signaling, restricting memory and alloantigen-specific immune response (By similarity). In the context of bacterial infection, acts as a ligand for TNFRSF14 on epithelial cells, triggering the production of antimicrobial proteins and pro-inflammatory cytokines.
Subcellular location: [CD160 antigen]: Cell membrane {ECO:0000269|PubMed:22801499, ECO:0000269|PubMed:25711213}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:O95971}.; SUBCELLULAR LOCATION: [CD160 antigen, soluble form]: Secreted {ECO:0000250|UniProtKB:O95971, ECO:0000305|PubMed:16177084}. Note=Released from the cell membrane by GPI cleavage. {ECO:0000250|UniProtKB:O95971, ECO:0000305|PubMed:16177084}.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 14
- B- and T-lymphocyte attenuator
- Tumor necrosis factor ligand superfamily member 14
- Lymphocyte activation gene 3 protein
- Killer cell lectin-like receptor subfamily G member 1
- Natural killer cell receptor 2B4
- Hepatitis A virus cellular receptor 2 homolog
- Cytotoxic T-lymphocyte protein 4
- Natural killer cells antigen CD94
- T-cell immunoreceptor with Ig and ITIM domains
Sequence:
MQRILMAPGQSCCALAILLAIVNFQHGGCIHVTSSASQKGGRLDLTCTLWHKKDEAEGLILFWCKDNPWNCSPETNLEQLRVKRDPETDGITEKSSQLVFTIEQATPSDSGTYQCCARSQKPEIYIHGHFLSVLVTGNHTEIRQRQRSHPDFSHINGTLSSGFLQVKAWGMLVTSLVALQALYTL
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (B3H746)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDANFEMPPVGGMNDDDDMDFGDGASFLKVGEEKEIQQGLKKKLLKEGEGYETPENGDEVEVHYTGTLLDGTKFDSSRDRATPFKFTLGQGQVIKGWDIGIKTMKKGENAVFTIPAELAYGESGSPPTIPANATLQFDVELLKWDSVKDICKDGGVFKKILAVGEKWENPKDLDEVLVKFEAKLEDGTVVGKSDGVEFTVKDGHFCPALTKAVKTMKKGEKVLLTVKPQYGFGEKGKPASAGEGAVPPNATLEINLELVSWKTVSEVTDDNKVVKKVLKEGDGYERPNEGAVVKVKLIGKLQDGTVFLKKGHGENEEPFEFKTDEEQVVDGLDRAVMKMKKGEVALVTIDPEYAFGSNESQQELAVVPPNSTVTYEVDLLTFDKERESWDMNTEEKIEAASKKKEEGNSKFKGGKYSLASKRYEKAVKFIEYDTSFSEEEKKQAKALKVACNLNDAACKLKLKDYKQAEKLCTKVLELESTNVKALYRRAQAYMELSDLDLAEFDVKKALEIDPNNREVKLEQKRLKEKMKEFNKKEAKFYGNMFAKLRIIKRWRGNEHLRS
Protein: Ras-related protein RABE1a (AtRABE1a) (Ras-related protein Rab8B) (AtRab8B) (O24466)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in membrane trafficking from the Golgi to the plasma membrane.
Subcellular location: Golgi apparatus membrane. Cell membrane {ECO:0000269|PubMed:15060130}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Rab escort protein 1
- Geranylgeranyl transferase type-2 subunit beta 2
- DEAD-box ATP-dependent RNA helicase 41
- Geranylgeranyl transferase type-2 subunit beta 1
- Protein YIP
- Reticulon-like protein B18
- Protein YIP4a
- Reticulon-like protein B5
- Exocyst complex component SEC6
- Reticulon-like protein B4
Sequence:
MAAPPARARADYDYLIKLLLIGDSGVGKSCLLLRFSDGSFTTSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWIRNIEQHASDSVNKILVGNKADMDESKRAVPKSKGQALADEYGMKFFETSAKTNLNVEEVFFSIAKDIKQRLADTDARAEPQTIKINQSDQGAGTSQATQKSACCGT