wanglab/gogpt-training-data huggingface dataset:
Protein: DNA damage-binding protein 1 (DNA repair protein E) (UV-damaged DNA-binding protein 1) (B0M0P5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Cullin-4
- WD40 repeat-containing protein
- RING-box protein 1
- WD40 repeat-containing protein
- DDB1- and CUL4-associated factor 7 homolog
- Uncharacterized protein
- COP9 signalosome complex subunit 5
- Uncharacterized protein
- SNF2-related domain-containing protein
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
Sequence:
MYNFVSTVQKPTSVTHSVTGNFTGPNDKNLIISKCTKIEIFLMDQDGLKPMFDVNIYGRISVLKLFSVAGSKQDYLFISTESFKFCILAYDYEKKEIITKASGNAEDTIGRPTEAGQLGIIDPDGRIVALHLYEGLLKLITLDNNNTPNKINNNNNNNNNNNNNNNNNNNNNINNNNFNINNNNNNSPIQKNVNNVRLEELQVLDMTFLYGCKVPTIAVLFKDTKDEKHISTYEISSKDTELVVGPWSQSNVGVYSSLLVPVPLGGVLVVADNGITYLNGKVTRSVAVSYTKFLAFTRVDKDGSRFLFGDHFGRLSVLVLIHQQQKVMELKFEQLGRISIPSSISYLDSGVVYIGSSSGDSQLIRLNTEKDQTTDSYVTYLEAFTNIGPVVDFCVVDAEKQGQAQIVTCSGTYRDGSLRIIRNGIGIAEQASIELEGIKGIFPINNNNNNNNNNNNNNNNNNNNNSNGITDSKDRYLITSFIECTKVLSFQGEEIEETEFEGLESNCSTLYCGTIDKLNLLIQITNVSINLIDSNTFKRVSQWNVEPSRRINLVSTNQDQIVLSIDKSLLYFQINSSNKSIQLVKEIELPHEISCIDISPFDSFMDTKSQLVSVGLWNDITLRIFKLPTLEEIWKEPLGGEILPRSILMISFDSIDYIFCSLGDGHLFKFQFDFSSFKLFDKRKLTLGTQPIILKKFKLKNTINIFAISDRPTVIYSHNKKLFYSVVNLKDVTNVTSFNSDGFPNSMAIATTNSLTIGTIDEIQKLHIKTIPLNEEMGRRIVHLEDHSCYAVITVKNNEGLLGGAQDLCEEDEEVSYIRIYNDQTFELISSYKLDPYEMGWSITPCKFAGDDVNTYLAVGTSINTPIKSSGRVLLFSLSSSSSSNDKDSLDNNNNNNNNSGANGKLTLLEEIKFRSSVYFLLSFNGRLIAAVHKRLFSIRYTHSKEKNCKVISSESVHKGHTMILKLASRGHFILVGDMMKSMSLLVEQSDGSLEQIARNPQPIWIRSVAMINDDYFIGAEASNNFIVVKKNNDSTNELERELLDSVGHYHIGESINSMRHGSLVRLPDSDQPIIPTILYASVNGSIGVVASISEEDFIFFSKLQKGLNQVVRGVGGFSHETWRAFSNDHHTIDSKNFIDGDLIETFLDLKYESQLKAVADLGITPDDAFRRIESLMQYIR
Protein: Basic leucine zipper 43 (AtbZIP43) (bZIP protein 43) (Q9FMC2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor involved in somatic embryogenesis. Acts as positive regulator of BHLH109.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Basic leucine zipper 61
- Transcription factor bHLH109
- Basic leucine-zipper 75
- Probable transcription factor At5g61620
- G-box-binding factor 4
- Transcription factor bHLH111
- Basic leucine zipper 34
Sequence:
MQPSTNIFSLHGCPPSYLSHIPTSSPFCGQNPNPFFSFETGVNTSQFMSLISSNNSTSDEAEENHKEIINERKQKRKISNRESARRSRMRKQRQVDELWSQVMWLRDENHQLLRKLNCVLESQEKVIEENVQLKEETTELKQMISDMQLQNQSPFSCIRDDDDVV
Protein: Transcription factor Sox-1b (Q2Z1R2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional activator.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
- Urotensin-related peptide 1.
Sequence:
MYSMMMETDLHSPGAQTNTNTGHTGPNSGSKVNQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLMSEAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAGSGGGGGVGLGMGAAGVGQRLESPVGHGGSTAASYAHMNGWTNGAYSGQVAAAAAAAAMMQEAQLAYGQHPGSGAHHHHGHHHHPHNPQPMHRYEMTALQYSPLSNSQSYMSASPSGYGGISYTQHQNSSVASSGAIGALGSLVKSEPSVSPPVNAHSRAPCSGDLREMISMYLPTAEAGDPSVQSRLHAVPQHYQSSTTSVNGTVPLTHI
Protein: Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C) (Q8T1G5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Has antibacterial activity.
Subcellular location: Cytoplasmic vesicle lumen {ECO:0000250}.
Interaction partners:
Sequence:
MRIAFFLLILSIIVGLAYGYSCPKPCYGNMCCSTSPDHKYYLTDFCGSTSACGPKPSCSGKLYFTADSQRFGCGKHLNLCRGKKCVKAKVYDAGPAEWVEKDAGKMIIDASPTICHELTGGSSCGWSDKFEITATVTSLTDSRPLGPFNVTEEEMDQLFIDHEIAMAQCEAEKTCNGFDLE
Protein: Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (dMED24) (Q9V439)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 20
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 11
- Mediator of RNA polymerase II transcription subunit 8
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 30
- Mediator of RNA polymerase II transcription subunit 4
- Mediator of RNA polymerase II transcription subunit 10
Sequence:
MASGSRTTILPQSKEALLKSYNARLKDDVRSMLENFEEILKLARRESHSQISKTTQCEQDALEMQVRAANMVRAGESLMKLVADLKQYLILNDFHSVNEAITNNSQLFRNTQSECDKKLMKLRDEMAMDLYDLEEEYYTSIFK
Protein: Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase 3 intronic transcript 1) (Thioredoxin reductase 3 neighbor gene) (Thioredoxin reductase TR2) (Q86VQ6)
Organism: Homo sapiens (Human)
Function: Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q99MD6}. Nucleus {ECO:0000250|UniProtKB:Q99MD6}. Microsome {ECO:0000250|UniProtKB:Q99MD6}. Endoplasmic reticulum {ECO:0000250}. Note=Detected in cytoplasm and nucleus in late spermatids. {ECO:0000250|UniProtKB:Q99MD6}.
Interaction partners:
- Selenide, water dikinase 2
- Selenocysteine lyase
- Thioredoxin
- Selenide, water dikinase 1
- Cystathionine gamma-lyase
- Kynurenine--oxoglutarate transaminase 3
- Kynurenine--oxoglutarate transaminase 1
- Thioredoxin reductase 2, mitochondrial
- Thioredoxin reductase 1, cytoplasmic
- Glutathione peroxidase 2
Sequence:
MERSPPQSPGPGKAGDAPNRRSGHVRGARVLSPPGRRARLSSPGPSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHSTRVKELFSSLGVECNVLELDQVDDGARVQEVLSEITNQKTVPNIFVNKVHVGGCDQTFQAYQSGLLQKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG
Protein: Transcription factor bHLH99 (Basic helix-loop-helix protein 99) (AtbHLH99) (bHLH 99) (Transcription factor EN 18) (bHLH transcription factor bHLH099) (Q9FKQ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Protein RALF-like 33
- Zinc finger protein 2
- Zinc finger CCCH domain-containing protein 14
- Transmembrane protein
- Protein RALF-like 24
- Secreted transmembrane peptide 5
- Transmembrane protein
- AT1G25275 protein
- At3g13845
- Succinate dehydrogenase assembly factor 4
Sequence:
MMFQQDYPHGFSLVETSLSYEMLDYFQNIVVSNSEDVASQQNSISSSSYSSATLSCSITEQKSHLTEKLSPLRERYGCGDFLSRKRRRRSEKTIVDKENQRMNHIAVERNRRKQMNHFLSILKSMMPLSYSQPNDQASIIEGTISYLKKLEQRLQSLEAQLKATKLNQSPNIFSDFFMFPQYSTATATATATASSSSSSHHHHKRLEVVADVEVTMVERHANIKVLTKTQPRLLFKIINEFNSLGLSTLHLNLTTSKDMSLFTFSVKVEADCQLTPSGNEVANTVHEVVRRVHKER
Protein: B3 domain-containing protein REM2 (Protein REPRODUCTIVE MERISTEM 2) (Q3E9T2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326}.
Interaction partners:
- Thioredoxin family protein
- AUGMIN subunit 8
- At3g10000
- Floral homeotic protein PISTILLATA
- Trihelix transcription factor PTL
- B3 domain-containing transcription factor VAL3
- Probable WRKY transcription factor 35
- Protein CRABS CLAW
- B3 domain-containing protein At5g42700
- Transcription factor HEC2
Sequence:
MDDPAISSPTNKHFFVIVLHGHKSSPMIPAEFFSTYVEGKNHQSTKLKLTSDAFDRTWEVKLNGRRFAGGWENFSTVHSLQDDDVVIFREIGDMTFHVTASGRSFCKLQYISSDEDRADEDDAWNVYSDSKNIVSKKKPRTEAESSSKNYYLVAHVTPSNLSRDRLYLIKAFARSNGLNERCCEIDLMNKHGKSWTLGLRYSTVNDQASISGGWRDFCLVNGLEAGSFYRFKLVQNGERPLLRLCYDTIPEEDCYKGNRKVNLSESASMKQGKFLTMTFKPYMLKSGQLRLSRPFAIENEIKEAEDITLVDKNGGNWPSYVASGDGQGGKYYLAKGWRSFCAANRLKTGETFTLEFVRGEGTTPMLKFCSKSKDKIEQVPFDEGGETQEETETRVKKRARVSAERGSSRRNQASNKPNADPQNLQPGQPHCSISDQVQKVKQIIVDTLTGIKRIRSELERKGQKLEASILEIDALGEKVSEINKILK
Protein: L-ornithine/L-arginine 3-hydroxylase (EC 1.14.11.-) (EC 1.14.11.41) (Alpha-ketoglutarate-dependent dioxygenase) (L-ornithine/L-arginine hydroxylase) (ODO) (C7Q942)
Organism: Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)
Function: Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-ornithine and L-arginine, leading to (3S)-3-hydroxy-L-ornithine and (3S)-3-hydroxy-L-arginine, respectively. Cannot use L-lysine, D-ornithine, or D-arginine as substrate.
Interaction partners:
Sequence:
MHRLALTAQDNLAVAPMLADLAGRYPDIEDPELIRSAPVLAAKGLPPHLLAFLDDFRLREPSALCVISGLDVDQDRLGPTPEHWRDSQIGSRSLNLEIFFLLCGAALGDVFGWATQQDGRIMHDVLPIKGHEHYELGSNSLQHLSWHTEDSFHPCRGDYVALMCLKNPYEAETMVCDAGDLDWPNLDVDALFEPVFTQMPDNSHLPQNTAESTGDPTKDRLRARSFELIKSWNENPVRRAVLYGDRQNPYMALDPYHMKMDDWSERSLEAFQALCEEIEAKMQDVVLHPGDIAFIDNFRAVHGRRSFRARYDGSDRWLKRLNITRNLRGSRAWRPAPDDRVIY
Protein: guanylate kinase (EC 2.7.4.8) (Q71RR7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAGPRPVVLSGPSGAGKSTLLKKLFQEHGSVFGFSVSHTTRNPRPGEEDGKDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLHPIYISVQPPSMDVLEQRLRQRNTETEESLAKRLAAAQADMESSKEPGLFDLVIVNDNLDEAYVTLKQALSEEIKKAEGTEHA
Protein: Perforin-like protein 1 (Q9U0J9)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKLRILKKHYYVVFILLYLYDISCFKCIRLNNRSIYKNKYKNNVHIGTNENIRSIEKYSNVLCNSILCKNDKISSFINQRKNVDDDDESENDDMYESTTAGSSSETDNESDEEENDSSDNNNSDEEQIENSNNNNSDEEQNDSSSNDNNDEENEEQDDVMDNDQNDKKIKHSFNLANESKHTKEERVKEEKKLKIYDFINDKEKRLNFNGDQKDEDNEENDDKDENTLENRNIISKHTSVFPGLYFIGIGYNLLFGNPLGEADSLIDPGYRAQIYLMEWALSKEGIANDLSTLQPVNGWIRKENACSRVESITECSSISDYTKSLSAEAKVSGSYWGIASFSASTGYSSFLHEVTKRSKKTFLVKSNCVKYTIGLPPYIPWDKTTAYKNAVNELPAVFTGLDKESECPSDVYEENKTKSNCENVSLWMKFFDIYGTHIIYESQLGGKITKIINVSTSSIEQMKKNGVSVKAKIQAQFGFGSAGGSTDVNSSNSSANDEQSYDMNEQLIVIGGNPIKDVTKEENLFEWSKTVTNHPMPINIKLTPISDSFDSDDLKESYDKAIIYYSRLYGLSPHDTMQKDDKDIIKILTNADTVTKNSAPPINAQCPHGKVVMFGFSLKQNFWDNTNALKGYNIEVCEAGSNSCTSKQGSSNKYDTSYLYMECGDQPLPFSEQVISESTSTYNTVKCPNDYSILLGFGISSSSGRINSAEYVYSTPCIPGMKSCSLNMNNDNQKSYIYVLCVDTTIWSGVNNLSLVALDGAHGKVNRSKKYSDGELVGTCPLDGTVLTGFKVEFHTSSPYVQTPFEKCAKSLKACSVHGSGHAIGIQNFKSLFIYMLCKNNK
Protein: Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) (P42893)
Organism: Rattus norvegicus (Rat)
Function: Converts big endothelin-1 to endothelin-1.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10491078, ECO:0000269|PubMed:8645169}; Single-pass type II membrane protein {ECO:0000269|PubMed:10491078, ECO:0000269|PubMed:8645169}.
Interaction partners:
- Endothelin-1
- Endothelin receptor type B
- Endothelin-1 receptor
- Endothelin-3
- Insulin-degrading enzyme
- Angiotensin-converting enzyme
- Angiotensin-converting enzyme
- Endothelin-2
Sequence:
MGSLRPPQGLGLQWSSFFLGKKGPGLTVSLPLLASSLQVNFRSPRSGQRCWAARTSVEKRLVVLVTLLAAGLVACLAALGIQYRTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASASEAEKKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEDSIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNAIFYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILEIKKAFEESLSTLKWMDEDTRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSLRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYNNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQILPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNPRHKCEVW
Protein: Adrenodoxin reductase, putative (EC 1.18.1.2) (Q38C21)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cytochrome oxidase assembly protein, putative
- Electron transfer protein, putative
- Adrenodoxin, putative
- NADH-ubiquinone oxidoreductase, mitochondrial, putative
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Electron transfer flavoprotein subunit beta
- Dihydroorotate dehydrogenase
- Flavoprotein monooxygenase, putative
- 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein
- Uncharacterized protein
Sequence:
MLLRRSHMRRCLKPGVPRHPPLSCASASPLQHTDVTSAPMKTQIAVVGSGPSGCYVAQQLIKKRDDIHVDVFERLPVPFGLCRYGVAPDHPEVKNVEQQFLSMFKSGRVTWIGNVDVGRQLPIDTLLNNYAAVVLATGVDSGKKLNIPGEDLGGVVRAADFVRYYNTYPFPHGSPRFCPFQLGMAHEAVVIGNGNVALDCTRVLAASYKYFCPTDMNCAAIKEFMKNHIHRIHVVGRRGPEHSAFTIAEFRELTKYQQDTVRVTVDAFNPEEARRASTENPRARQRLFELMGRHIVKSDDPESQEVRGPTIPKGTRGPCHIRFRYNMRPLRFLPHRERKGQVGAVVFECTAAETSSSTDCAAATETQAYDANCGEGGNKGGGTGVKAPKVITVPCDLVITSLGYYGDSIPGVEFDHARGVISHVGGRVKGQPRLYCAGWAKNGPKGIIAHALMDAQVTAATVLEDLDNSALPTGGSDGAFCGKYGLVDYFVEKRMEPVSVAGLERIMHVELERGVDMGKRLEKIDDVRAMLDVALGGAVGKKANNAIRGIMNERPDALLYLNELLDDTTDLAPLARQLARDLPPVMAEQHPPGRLHPSQL
Protein: Ribonuclease P/MRP protein subunit POP5 (EC 3.1.26.5) (RNA-processing protein POP5) (RNase P/MRP 19.6 kDa subunit) (P28005)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Ribonuclease P protein subunit RPR2
- Ribonucleases P/MRP protein subunit POP6
- Ribonucleases P/MRP protein subunit POP3
- Ribonucleases P/MRP protein subunit POP7
- Ribonuclease MRP protein subunit RMP1
- Ribonuclease P/MRP protein subunit RPP1
- Ribonucleases P/MRP protein subunit POP8
- Ribonucleases P/MRP protein subunit POP1
- RNases MRP/P 32.9 kDa subunit
- 13 kDa ribonucleoprotein-associated protein
Sequence:
MVRLKSRYILFEIIFPPTDTNVEESVSKADILLSHHRASPADVSIKSILQEIRRSLSLNLGDYGSAKCNSLLQLKYFSNKTSTGIIRCHREDCDLVIMALMLMSKIGDVDGLIVNPVKVSGTIKKIEQFAMRRNSKILNIIKCSQSSHLSDNDFIINDFKKIGRENENENEDD
Protein: Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) (P43636)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15044395}; Multi-pass membrane protein {ECO:0000269|PubMed:15044395}.
Interaction partners:
- Chitobiosyldiphosphodolichol beta-mannosyltransferase
- GDP-Man:Man
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- Man
- Phosphomannomutase
- UDP-N-acetylglucosamine transferase subunit ALG13
- Mannitol dehydrogenase DSF1
- Dolichol-phosphate mannosyltransferase
- Mannose-1-phosphate guanyltransferase
- Dol-P-Man:Man
Sequence:
MIEKDKRTIAFIHPDLGIGGAERLVVDAALGLQQQGHSVIIYTSHCDKSHCFEEVKNGQLKVEVYGDFLPTNFLGRFFIVFATIRQLYLVIQLILQKKVNAYQLIIIDQLSTCIPLLHIFSSATLMFYCHFPDQLLAQRAGLLKKIYRLPFDLIEQFSVSAADTVVVNSNFTKNTFHQTFKYLSNDPDVIYPCVDLSTIEIEDIDKKFFKTVFNEGDRFYLSINRFEKKKDVALAIKAFALSEDQINDNVKLVICGGYDERVAENVEYLKELQSLADEYELSHTTIYYQEIKRVSDLESFKTNNSKIIFLTSISSSLKELLLERTEMLLYTPAYEHFGIVPLEAMKLGKPVLAVNNGGPLETIKSYVAGENESSATGWLKPAVPIQWATAIDESRKILQNGSVNFERNGPLRVKKYFSREAMTQSFEENVEKVIWKEKKYYPWEIFGISFSNFILHMAFIKILPNNPWPFLFMATFMVLYFKNYLWGIYWAFVFALSYPYEEI
Protein: Transcription initiation factor TFIID subunit 2 (TBP-associated factor 2) (AtTAF2) (Q8LPF0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription initiation factor TFIID subunit 13
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 11
- Transcription initiation factor TFIID subunit 7
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 4b
- Transcription initiation factor TFIID subunit 4
Sequence:
MAKARKPKNEEAPGAKTSENTGAKVLHQKLFLSIDFKKRQIYGYTELEVSVPDIGIVGLHAENLGIESVLVDGEPTVFEYYPHHQNSETESNWNSVSDPASAADAAAMEYVGVLKREDTANLLINCCKPSKDLSEQLDSVTLENGSQSSGEAKQNVKLIRINYWVEKIESGIHFDGNIVHTDNQMRRARCWFPCIDDEYHRCSFDLEFTVPHNFVAVSVGKLLYQVMCKEDTTQKTYVYELAIPIAPRWVSLVAGPLEILPDQTNFLISNLCLPHDLSRLRNTMEFFHEAYSYYEDYLSANFPFGFYKQVFLPPEMVVTSSTSGASLSIFSSHILYDERVIDQTIDTRIKLASALAKQWFGVYITPESPNDDWLLDGLAGFLTDMFIKQFLGNNEARYRRYKANCAVCKADDSGAMCLSSSPSCRDLFGTHSIGMHGKIRSWKSGAVLQMLEKQMGSDSFRKILQKIISRAKDPSNSIRSLSTKEFRQFANKIGNLERPFLKEFFQRWVASYGCPVLRIGLSYNKRKNNVEMAALRECTAALDARLSVIGATSDSESRDVDAGWPGIMSIRVYELDGMSDHPKLPMAGDRWQLLELPCHSKLAAKRYQKPKKGGKPDGAEDNVDAIAPLENKTSIESPLAWIKADPEMEYIAEIHLHQPLQMWVNQLEKDGDVVAQAQAIASLEALKQHSFSIVNALKNVLTDSKVFWRIRIAAAFALAKTASEESDWAGLQHLIKFYKSRRFDAEIGLPKPNDFRDFPEYFVLEAIPHAIAIVRGAEGKSPREAVEFILQLLKYNDNSGNSYSDVFWLAVLVQSVGDLEFCQQSLTFLAPLLKRIDRLLQFDRLMPSYNGILTISCIRTLAQTALKLSDSISFDHICKLIEPFRNSDTILQIRIEGSRALLDIEYQSKGISSALLLFMKYLVEESSLRGQVKLCVHTMRLCQIAVGCDSDDCVDTVTLLDLLHLFKSHVVFNNELLRYYLFCIFQILAGRPPTLFGVPKEKPLQLVDVEACIEPKNVFLVPGAEAGEPSLSALGDAKGQSLDVAPYGVPIIPQEMFMPIVPELMLPEPVAAYDETQHLEPRMESQNQPSHENPIVHEIPSDVEGPTEELAHREANPPTKEPQKEPDVVSVSVSHEVKKSVIRIKVRPSGATSRAEGSARTIERSQGIVVRHDIDRGQTSSASVDAPQRISTDAVSISNQNHVEEVNSCHDVGSRMTASIGSVKFASEGDIFGKELQCTAESGKPSTSQKADNNNRTVPPSFLPLDHSMENEAQQKYASLQTLSIGKEKEKKKDKEKKEKKRKREDPVYLEKKRLKKEKKRKEKEMAKLVSSTTDPAKKKIESVAEVKEEEPSDGAMLIKVEPKTEPSTAEARPLPKFRIKLKSKAFNNS
Protein: GATA-binding factor C (Protein grain) (Transcription factor GATA-C) (dGATA-C) (P91623)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor that is vital to the development of multiple organ systems. Binds to the core consensus sequence 5'-WGATAR-3'.
Subcellular location: Nucleus {ECO:0000269|PubMed:7559649}.
Interaction partners:
Sequence:
MDMTSTAEAAARSWYDSPRLGGGGSSGGGNGGGVSPQTNGLGSAGSSLAHSHHSLSSGASSAGSSVGVGSALGGGGGSGLDTSDMSAFYALESNGHHRRYYPSYHQHTSRMPSTHASPQVCRPHFHTPLSPWLTSEHKSFAPASAWSMGQFACPQEPQVEHKLGQMGQSHQTTAAGQHSFPFPPTPPKDSTPDSVQTGPSEYQAVMNAFMHQQATGSTSLTDASCALDIKPSIQNGSASGSSGSGTTHTSTPKQREEGRECVNCGATSTPLWRRDGTGHYLCNACGLYYKMNGQNRPLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKLSSKSKKKKGLGGGCLPIGGHLGMGDFKPLDPSKGFGGGFSASMAQHGHLSSGLHPAHAHMHGSWYTGGMGALGASSGLQGGFSTAGSLSGAVVPHSQPYHLGLSSMGTWRTDYT
Protein: N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120) (Q14CX7)
Organism: Homo sapiens (Human)
Function: Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. May play a role in normal cell-cycle progression.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18570629}.
Interaction partners:
- N-alpha-acetyltransferase 20
- N-alpha-acetyltransferase 15, NatA auxiliary subunit
- N-alpha-acetyltransferase 30
- N-alpha-acetyltransferase 35, NatC auxiliary subunit
- N-alpha-acetyltransferase 10
- N-alpha-acetyltransferase 50
- N-alpha-acetyltransferase 16, NatA auxiliary subunit
- N-alpha-acetyltransferase 11
- Serine/threonine-protein kinase PAK 4
- SH2B adapter protein 3
Sequence:
MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWSPPAEGEHSLEGEVHYSAEKAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKTCLKTELQFSDYYCLLAVHALIDVWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEDLRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETLWLRIRSLTLRLISGLPSLNHPVEPKNSEKTAENGVSSRIDILRLLLQQLEATLETGKRFIEKDIQYPFLGPVPTRMGGFFNSGCSQCQISSFYLVNDIYELDTSGLEDTMEIQERIENSFKSLLDQLKDVFSKCKGDLLEVKDGNLKTHPTLLENLVFFVETISVILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSPEERKFSKTVQGKVQSSYLHSLLEMGELLKKRLETTKKLKI
Protein: Dynactin subunit 6 (Dynactin subunit p27) (Protein WS-3) (O00399)
Organism: Homo sapiens (Human)
Function: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:D0G6S1}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:23455152}.
Interaction partners:
- Dynactin subunit 1
- Actin-related protein 10
- Dynactin subunit 2
- Dynactin subunit 5
- Dynactin subunit 4
- Dynactin subunit 3
- Alpha-centractin
- Beta-centractin
- Cytoplasmic dynein 1 heavy chain 1
- F-actin-capping protein subunit beta
Sequence:
MAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKTMKGSSTPVKN
Protein: Catenin delta 1 (D3ZZZ9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
Interaction partners:
- Cadherin-1
- Catenin beta-1
- Cadherin-2
- Cadherin-5
- Receptor protein-tyrosine kinase
- Transforming protein RhoA
- Tyrosine-protein kinase Fyn
- Catenin alpha-1
- Receptor-type tyrosine-protein phosphatase eta
- Junction plakoglobin
Sequence:
MANGTLTRRHQNGRFVGDADLERQKFSDLKLNGPQDHNHLLYSTIPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTMTTRTVQPVPMGPDGLPVDASAVSNNYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYGRHYEDGYPGGSDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDLDYGMMSDYGTARRTGTPSDPRRRLRSYEDMIGEEVPPDQYYWAPLAQHERGSLASLDSLRKGMPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPILVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEALPSVANSTGPHAASCFGAKKGKDEWFSRGKKPTEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTSEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDNNYSTLNERGDHNRTLDRSGDLGDMEPLKGAPLMQDEGQESLEEELDVLVLDDEGNQVSYPPMQKI