wanglab/gogpt-training-data huggingface dataset:
Protein: Ribosomal protein eL39-like 2 (60S ribosomal protein L39-2) (60S ribosomal protein L39-like) (Large ribosomal subunit protein eL39-like) (Q96EH5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9CQD0}.
Interaction partners:
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein eL36
- Large ribosomal subunit protein eL15
- Small ribosomal subunit protein eS19
Sequence:
MSSHKTFTIKRFLAKKQKQNRPIPQWIQMKPGSKIRYNSKRRHWRRTKLGL
Protein: Candida glabrata strain CBS138 chromosome E complete sequence (Q6FVE4)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome L complete sequence
- Negative regulator of the PHO system
- Cyclin-dependent kinase 1
Sequence:
MTPQDAQINTDEEIPTIKLPRDFLKCPKGDLVILIARMLQFIIQINDSNIKENERKYGLTRFHSKIAPNISVFNYFTRLTKYSLLEHSVLLSAVYYIDLLSNVYPAFNLNSLTAHRFLLTATTIASKGLCDSFCTNTHYSKVGGVQCNELNVLENEFLRKVNYRIIPRDNNITFCKMEVQKNFFILPESIESDLAPSLRQGYSSISNAGYNVLTRYYYKIIEVVGKYSSSPDKTKKVNYDIDMPAKTLHEHQQNDAVKNCSNNNSNYQTASNNIPIPQTIPQNRPKRNFDTVEERHNIYIEEKSKMNTNGLAEKLTSSSYKKQITEDKKNQILDNSIYPSSI
Protein: Endophilin-B2 (SH3 domain-containing GRB2-like protein B2) (Q9NR46)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11161816}.
Interaction partners:
- Endophilin-B1
- SH3 domain-containing kinase-binding protein 1
- E3 ubiquitin-protein ligase CBL-C
- E3 ubiquitin-protein ligase CBL-B
- E3 ubiquitin-protein ligase CBL
- Myc box-dependent-interacting protein 1
Sequence:
MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS
Protein: Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) (Q05911)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Bifunctional purine biosynthesis protein ADE16
- Adenylosuccinate synthetase
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bifunctional purine biosynthetic protein ADE5,7
- Bifunctional purine biosynthesis protein ADE17
- Amidophosphoribosyltransferase
- Adenine phosphoribosyltransferase 1
- Phosphoribosylformylglycinamidine synthase
- Adenine phosphoribosyltransferase 2
- Phosphoribosylglycinamide formyltransferase
Sequence:
MPDYDNYTTPLSSRYASKEMSATFSLRNRFSTWRKLWLNLAIAEKELGLTVVTDEAIEQMRKHVEITDDEIAKASAQEAIVRHDVMAHVHTFGETCPAAAGIIHLGATSCFVTDNADLIFIRDAYDIIIPKLVNVINRLAKFAMEYKDLPVLGWTHFQPAQLTTLGKRATLWIQELLWDLRNFERARNDIGLRGVKGTTGTQASFLALFHGNHDKVEALDERVTELLGFDKVYPVTGQTYSRKIDIDVLAPLSSFAATAHKMATDIRLLANLKEVEEPFEKSQIGSSAMAYKRNPMRCERVCSLARHLGSLFSDAVQTASVQWFERTLDDSAIRRISLPSAFLTADILLSTLLNISSGLVVYPKVIERRIKGELPFMATENIIMAMVEKNASRQEVHERIRVLSHQAAAVVKEEGGENDLIERVKRDEFFKPIWEELDSLLEPSTFVGRAPQQVEKFVQKDVNNALQPFQKYLNDEQVKLNV
Protein: Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Q32PH0)
Organism: Bos taurus (Bovine)
Function: Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Subcellular location: Golgi apparatus, cis-Golgi network {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Processes and cell bodies of neurons. {ECO:0000250}.
Interaction partners:
- Trafficking protein particle complex subunit 10
- Trafficking protein particle complex subunit 2
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit 1
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit 2-like protein
- Trafficking protein particle complex subunit 4
- Trafficking protein particle complex subunit 6B
- Trafficking protein particle complex subunit 6A
- Trafficking protein particle complex subunit 8
Sequence:
MSVPDYMQCAEDHQTLLVVVQPVGIVSEENFFRIYKRISSVSQISVRDSQRALYIRYRHHYPPENSEWGDFQTHRKVVGLITITDCFSAKDWPQIFEKFHVQKEIYGSTLYDSRLFVFGLQGEIAEQPRTDVAFYPSYEDCATVEKRIEDFVESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKAGARRFPGSALPAEAANRHRPGALTTNGINADTSTEIGRAKNCLSPEDIIEKYKEAISYYSKYKNAGVIELEACVKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSISEPGWRACYKLLLETLPGYSLSLDPQDFNKGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVTQSLENYTSKCPGTMELLTLPDGLTLPPVPFTKLPIVRRVKLLDLPASLRPQKMKSSLGPSVSAKSPFIYSPIIAHSRGEERSKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVSGYHTTVFGVFSDCLLDSLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDKISTNVSVQLYNGETQQLVVRLENIGMEPLEKLEVTSKILTTKEKLYGDFLSWKLEDTLAQFPLQPGKVATFTISIKVKLDFSCQENLLQDLSDDGISVSGFPLCSPFRQVVRPRVESKPVNAAEGGRPGEPCHVKTLEAVLNFKYSGGPGHVEGYYRNLALGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNATEHELSVGARSDEELILHAGECQRMAIQVDKFNFESFPESPADKGQFANSKHLEEERQEARGLEINSKLDIHWTIPSLKRTGEASVEGLLNQLVLEHLQLAPLLWDVLVDGQPCDCQAAACRVGDPVRLEVRLTNRSPRSVGPFALSVVPFQDHQNGVHSYDLRHAVSFVGSGTFYLDKVQPSGQAACLGALLFLYTGDFFLHIRFHEDGPSKELPPSWFCLPSVHVRALEAQA
Protein: mRNA transport factor GFD1 (Good for full DBP5 activity protein 1) (Q04839)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High-copy suppressor of mutant alleles of ATP-dependent RNA helicase DBP5, which is involved in mRNA export from the nucleus. It may also play an important role in a late stage of NAB2-mRNA export.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10523319}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:10523319}. Nucleus membrane {ECO:0000269|PubMed:10523319}; Peripheral membrane protein {ECO:0000269|PubMed:10523319}; Cytoplasmic side {ECO:0000269|PubMed:10523319}.
Interaction partners:
- mRNA export factor GLE1
- Nuclear polyadenylated RNA-binding protein NAB2
- ATP-dependent RNA helicase DBP5
- Nucleoporin NUP42
- Protein MLP1
Sequence:
MPLESIWADAPDEEPIKKQKPSHKRSNNNKKNNNSRWSNESSSNNKKKDSVNKVKNNKGNHESKTKNKIKETLPREKKPPHSQGKISPVSESLAINPFSQKATEISPPPVSPSKMKTTKTQSKQDTASKMKLLKKKIEEQREILQKTHHKNQQQQVLMDFLNDEGSSNWVDDDEEELILQRLKTSLKI
Protein: Tissue-resident T-cell transcription regulator protein ZNF683 (Homolog of Blimp-1 in T-cell) (Hobit) (Zinc finger protein 683) (Q8IZ20)
Organism: Homo sapiens (Human)
Function: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Also plays a role in the differentiation of both thymic and peripheral NKT cells. Negatively regulates the accumulation of interferon-gamma (IFN-gamma) in NKT cells at steady state or after antigenic stimulation. Positively regulates granzyme B production in NKT cells after innate stimulation. Associates with the transcriptional repressor PRDM1/BLIMP1 to chromatin at gene promoter regions.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Granzyme H
- T-cell surface glycoprotein CD8 alpha chain
Sequence:
MKEESAAQLGCCHRPMALGGTGGSLSPSLDFQLFRGDQVFSACRPLPDMVDAHGPSCASWLCPLPLAPGRSALLACLQDLDLNLCTPQPAPLGTDLQGLQEDALSMKHEPPGLQASSTDDKKFTVKYPQNKDKLGKQPERAGEGAPCPAFSSHNSSSPPPLQNRKSPSPLAFCPCPPVNSISKELPFLLHAFYPGYPLLLPPPHLFTYGALPSDQCPHLLMLPQDPSYPTMAMPSLLMMVNELGHPSARWETLLPYPGAFQASGQALPSQARNPGAGAAPTDSPGLERGGMASPAKRVPLSSQTGTAALPYPLKKKNGKILYECNICGKSFGQLSNLKVHLRVHSGERPFQCALCQKSFTQLAHLQKHHLVHTGERPHKCSIPWVPGRNHWKSFQAWREREVCHKRFSSSSNLKTHLRLHSGARPFQCSVCRSRFTQHIHLKLHHRLHAPQPCGLVHTQLPLASLACLAQWHQGALDLMAVASEKHMGYDIDEVKVSSTSQGKARAVSLSSAGTPLVMGQDQNN
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (Q9N1N9)
Organism: Equus caballus (Horse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MQSWGTIICIRILLRFLLLWVLIGNSHTEEDIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSNIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPRVSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTKKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEILSRSIMKRWANFAKYGNPNGTQSNSTRWPVFKSTEQKYLTLNTESPKVYTKLRAQQCRFWTLFFPKVLELTGNIDEAEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCSDF
Protein: PB1 domain-containing protein (Q38CG8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPKKSEPVAPVTSARSSSPTCRPPVHPSSLGEWVNDSVNQENVKGEAANRFHPESMRGVDSLFYRPPVQQMKTPPRGGPLGEVNADPLGELEAILTYVEHVTVSLTRRERVSPPPESLRTLHGSLVTFRRAVNTSDRESTTRRALAAELHDQAATLLAWIARLEYVSISQSISLRELEKEVGASAANIDAVLDAIEVRYRNHDVADVQEFFMGSRETLKSCRSAVSDLVGGARKVLVLRRAVASREAVRVKELFGEYWGNKGGGGTVRIVCPFVDWVEKSWFPAIEKWEAIVSGAKKEAELGDVKGAFARAQRLALTESSMIGKIIQPGETLSELLHQYLEEPLAAVEQSLKRRKSRMEALRVAMTTKDGKRLAECLCAVEELRAGKELSAEDTELAEKARKQIVHLQQVGNITMALRLAVQAGETVTLFRTIHQANELLLQLGIVGNPEAGEETVQRCNTLLREMQNLPSGVSLTDFVVKRVNPMKMNLAHVPSHVWTSETTAAYQAAWQRLATRAMQGLCRFQHESDPESDSGTAHGLHTRSNSGLSCGSHSVRGGGNAIAAFTRTRTQQTEVGNPQNEWSHVQFGSWVEPAASERALAGRARSSDVDGFKLKIHFEAQLRVLRIQGTETCTFDEVYKRVHDLCTQQTALHHRPAGQKLRLRYEDAEGDCISLLTQEDWNVFISEQAPSGLRGAKLEIYCDFPPVPSQSTLDRTPLSTTSKDGGSSPTVKNTPQTTTSARLATGGTQMKPLLESDQAKGAKPSRCQSAGIAHRRGNGVSRLVSNRRVSHDDFHVPKQTPKTPAGMGTSADGGKDALEIGVPRDFDAAVHEREVPKRIGAAPSVSYTQPRAFPVKQTTSSGNAMRVSPKVGRPLGTAAEAKKLRTPPKLVGGDVKNAVRGAGLAGNLAVEEPVEAIEAKKWKDDETGMESDVVTSTISQARTPISQRKAPSRVVSAMKQTVPRSAVTGHHVNSRVRNAPVGGIPCDAAVVEEKREWSVYHFRPSEIHPVANDREETPPSVGSRVKGALVTERLSGSSSTSIPNSTTTLNGGAKKAEALIRYRQLREEKQRALKAAVQKRISK
Protein: Structure-specific endonuclease subunit SLX1 homolog (EC 3.1.-.-) (GIY-YIG domain-containing protein 1) (P91351)
Organism: Caenorhabditis elegans
Function: Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (Potential). Has a preference for replication forks over 5' flap structures or Holliday junctions and shows much lower activity toward 3' flap structures. Required for proper crossover distribution through inhibition of crossover formation at the central region of chromosomes.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03100}.
Interaction partners:
- SAP domain-containing protein
- Crossover junction endonuclease MUS81
- ERCC1-like central domain-containing protein
- GEN1 Holliday junction resolvase homolog
- DNA repair endonuclease XPF
- RecQ-like DNA helicase blm-1
- Exonuclease 1
- DNA topoisomerase 3
- Probable actin-related protein 2/3 complex subunit 4
- DNA mismatch repair protein S5 domain-containing protein
Sequence:
METFILSSDSDDDSGPPPSKRRTIEGIPRSFSGDKKIRFSFGASNMSQDTTQEIIPEDTDTVPLTIPSTPALSGKFDSKTPKSVRRRSVSMSCFTPIVETINQPPTNQACSSFLQKEYNFHDLSSDEEGGDGGAGCSKDEDKIIEDNLNLRALLSPEKKKRKEKIEEVQNEFYGVYCLISRSDRPCYKNRCYIGYTVDPNRRIMQHNGGRDKGGAKKTDSRGPWDMVCVVHGFPNHVAALHFEWAWQNPLVSKSLKEKQLRKERKETPFAFQLRIACELMNSSAFCRFALTFRWLITTEELPFPTSCVPPDHTKLRFGKVKKEMSLVPSKREDYLEMGECRICGKDIEKLWSLVRCISATCPSHFHSKCLSENGLKLKNEHVDHVYPLKANCPTCGQFYLWGDIIREQRRIIKISTKCAEEFQNMVVRKELPHREISPISSKK
Protein: Zinc finger protein 217 (O75362)
Organism: Homo sapiens (Human)
Function: Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- REST corepressor 1
- C-terminal-binding protein 1
- Histone deacetylase 2
- C-terminal-binding protein 2
- Histone deacetylase 1
- Lysine-specific histone demethylase 1A FAD-dependent demethylase 1A)
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
- PHD finger protein 21A
- Nuclear receptor coactivator 3
- Breast carcinoma-amplified sequence 1
Sequence:
MQSKVTGNMPTQSLLMYMDGPEVIGSSLGSPMEMEDALSMKGTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVAAEVKNDGKNQDTEDALLTADSAQTKNLKRFFDGAKDVTGSPPAKQLKEMPSVFQNVLGSAVLSPAHKDTQDFHKNAADDSADKVNKNPTPAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLEVSPKEKQTETAADCRYRPSVDCHEKPLNLSVGALHNCPAISLSKSLIPSITCPFCTFKTFYPEVLMMHQRLEHKYNPDVHKNCRNKSLLRSRRTGCPPALLGKDVPPLSSFCKPKPKSAFPAQSKSLPSAKGKQSPPGPGKAPLTSGIDSSTLAPSNLKSHRPQQNVGVQGAATRQQQSEMFPKTSVSPAPDKTKRPETKLKPLPVAPSQPTLGSSNINGSIDYPAKNDSPWAPPGRDYFCNRSASNTAAEFGEPLPKRLKSSVVALDVDQPGANYRRGYDLPKYHMVRGITSLLPQDCVYPSQALPPKPRFLSSSEVDSPNVLTVQKPYGGSGPLYTCVPAGSPASSSTLEGKRPVSYQHLSNSMAQKRNYENFIGNAHYRPNDKKT
Protein: Trans-3-hydroxy-L-proline dehydratase (T3LHyp dehydratase) (t3HypD) (EC 4.2.1.77) (Trans-L-3-hydroxyproline dehydratase) (Q0B950)
Organism: Burkholderia ambifaria (strain ATCC BAA-244 / DSM 16087 / CCUG 44356 / LMG 19182 / AMMD) (Burkholderia cepacia (strain AMMD))
Function: Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline. Displays neither trans-4-hydroxy-L-proline (t4LHyp) epimerase nor proline racemase activity.
Interaction partners:
Sequence:
MKISRSLSTVEVHTGGEAFRIVTSGLPRLPGDTIVQRRAWLKENADEIRRALMFEPRGHADMYGGYLTEPVSPTADFGVIFLHNEGYSDHCGHGVIALSTAAVELGWVQRTVPETRVGIDAPCGFIEAFVQWDGEHAGPVRFVNVPSFIWRRDVSVDTPSFGTVTGDIAYGGAFYFYVDGAPFDLPVREAAVEKLIRFGAEVKAAANAKYPVVHPEIPEINHIYGTIIANAPRHPGSTQANCCVFADREVDRSPTGSGTGGRVAQLYQRGVLAAGDTLVNESIVGTVFKGRVLRETMVGDIPAVIPEVEGSAHICGFANWIVDERDPLTYGFLVR
Protein: Phenylalanine ammonia-lyase 4 (EC 4.3.1.24) (Q9SS45)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Trans-cinnamate 4-monooxygenase
- 4-coumarate--CoA ligase 1
- 4-coumarate--CoA ligase 2
- 4-coumarate--CoA ligase 3
- 4-coumarate--CoA ligase-like 7
- 4-coumarate--CoA ligase 4
- 4-coumarate--CoA ligase-like 6
- 4-coumarate--CoA ligase-like 9
- 4-coumarate--CoA ligase-like 1
- Chalcone synthase
Sequence:
MELCNQNNHITAVSGDPLNWNATAEALKGSHLDEVKRMVKEYRKEAVKLGGETLTIGQVAAVARGGGGSTVELAEEARAGVKASSEWVMESMNRGTDSYGVTTGFGATSHRRTKQGGALQNELIRFLNAGIFGPGAGDTSHTLPKPTTRAAMLVRVNTLLQGYSGIRFEILEAITKLLNHEITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGPSGETLTASEAFKLAGVSSFFELQPKEGLALVNGTAVGSGLASTVLFDANILAVLSEVMSAMFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKEAQLLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVAMDNSRLAIASIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTAEAVDILKLMSTTYLVALCQAVDLRHLEENLKKAVKSAVSQVAKRVLTVGANGELHPSRFTERDVLQVVDREYVFSYADDPCSLTYPLMQKLRHILVDHALADPEREANSATSVFHKIGAFEAELKLLLPKEVERVRVEYEEGTSAIANRIKECRSYPLYRFVRDELNTELLTGENVRSPGEEFDKVFLAISDGKLIDPLLECLKEWNGAPVSIC
Protein: Conserved protein (O69667)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Conserved protein
Sequence:
MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG
Protein: Bifunctional protein FolD 4, chloroplastic (Protein EMBRYO DEFECTIVE 3127) (Tetrahydrofolate dehydrogenase/cyclohydrolase 4) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] (O65271)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:18431481}.
Interaction partners:
- Formate--tetrahydrofolate ligase
- Bifunctional dihydrofolate reductase-thymidylate synthase 2
- Bifunctional dihydrofolate reductase-thymidylate synthase 1
- 5-formyltetrahydrofolate cyclo-ligase-like protein COG0212
- 5-formyltetrahydrofolate cyclo-ligase, mitochondrial
- Formyltetrahydrofolate deformylase 1, mitochondrial
- Bifunctional dihydrofolate reductase-thymidylate synthase
- Formyltetrahydrofolate deformylase 2, mitochondrial
- Glycine cleavage system H protein 2
- Glycine cleavage system H protein 3
Sequence:
MASMMFTDCSSTTTSRLIHLNRSSGTFLLRQCVGQLRLQTTASGRGCCIRSSSSPISSISADTKSEGGAIVIDGKAVAKKIRDEITIEVSRMKESIGVIPGLAVILVGDRKDSATYVRNKKKACDSVGIKSFEVRLAEDSSEEEVLKSVSGFNDDPSVHGILVQLPLPSHMDEQNILNAVSIEKDVDGFHPLNIGRLAMRGREPLFVPCTPKGCIELLHRYNIEIKGKRAVVIGRSNIVGMPAALLLQREDATVSIIHSRTKNPEEITREADIIISAVGQPNMVRGSWIKPGAVLIDVGINPVEDPSAARGYRLVGDICYEEASKVASAITPVPGGVGPMTIAMLLSNTLTSAKRIHNFQ
Protein: MIP06926p (Myofilin, isoform A) (Myofilin, isoform G) (Myofilin, isoform N) (Q9VFC6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFKNHLEMIGRNESPSKKAKFWQSYIRSLKGSEDIRAHEAPRASRPYSSYLDSPSYRSIYDEPATANERVQSSGYRYLPVSRDTYGYSPRAIYDHHYSRTKKAWNDHLKRMQEIERRYPSRYGLYLRDKPLTPNSLVPLEYEPEDKLLAELNKAIRV
Protein: Transcription factor BYE1 (Bypass of ESS1 protein 1) (P36106)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Negative regulator of transcription elongation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00651}.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase II subunit RPB11
- Peptidyl-prolyl cis-trans isomerase ESS1
- DNA-directed RNA polymerase II subunit RPB3
- F-actin-capping protein subunit alpha
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
Sequence:
MSVRTSSRSNKGQNKYIEYLLQEETEAPKKKRTKKKVDSAIEKNKKSDSSQEPRKDTENVRTDEVDEADEGYVRCLCGANNENYDAAEYSHGDMVQCDGCDTWQHIKCMTDGKDTIDGLMSEDSKYYCELCDPSLYAHLETSKEAEVSEDEDYHDDVYKPVNDHDDNDADVFLDEESPRKRKRSPDSAKGIHIKSKQVKKSNGSKKRNKSIDAAKSDTAENEMPTRKDFESEKEHKLRYNAEKMFSTLFSKFIVPETIEAKLYELPDGKDVISISQEFAHNLEEELYKACLNVEFGTLDKIYTEKVRSLYSNLKDKKNLELKAHVVEGKLPLNKLVNMNASELANPDLQEFKEKRDKIILENFIVEVPDKPMYVKTHKGDELIEDIAEPQEDILYSKDSIRLHNIDSIDSDKSKIEQTHAISKEPSPSTIINEESLNCAFLYPGLGLEFTGYLNYIGASQKLRRDIFKEAIGDGKLYVEGRLPTTTAAPYLKEISCSRAILVYQLFPSNDSESKTTFADVVDSLENKGRIAGIKPKTRYEKDFYIVPSKGGEIPEILKDILGSHNDERSERFSRMKSDERTLFAFVVVKQEFIH
Protein: Guanine nucleotide-binding protein subunit beta-like protein (Q57YN4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- MPN domain-containing protein
- Ubiquitin fusion degradation protein, putative
- Ubiquitin thioesterase OTU
- UBX domain-containing protein
- Polyubiquitin, putative
- SEP domain-containing protein
- UBX domain-containing protein 11
- Cell division cycle protein, putative
- Valosin-containing protein homolog, putative
- AAA ATPase, putative
Sequence:
MSKAPELCYLLRAEGRIHTADVRHVSSSSGLLLTSSRDQTTFVIDAPGTTPWPSGDDFPTGLTLTGHTAFVNFAIMHSGIPLLGGEPCVITGGNDKHVALWNPQTAALEAVLDSHSHGVCCGLVVTSTVAEGAGHDGSVGDIVTGDWGGMCLVFDATTGDVKQCYRGHSTAVRSITQLPRTSSIVSASGDKTLHQWNVATGEEIAVYTGHTDVVQCVCAISSTRFASGSNDTTIIIWDTTVGTHPLRSLLMHHSLVYSLCFCNDRQLLFSASEDCTVKVISGASTVSAPTVGSSVDVGDVAVVQSINHPCVVWSVCTTEVGDIVTGAADGAVRVWTLNDELMASVGKLEALAEAVATQKLDIKITSIAGTNIADLPPVEQLHQKKGVQEGERCFVRTKGETVEVYAWDQGRWEKIGIVTEGTQGQPYTGAQSGSAAQKPKVYFNGVPYDYVFDVDVNGTMLKLPYNRGQNIFDAAQDFINKNSAVVSQTHKEEIQNFILNNIDPQDALLLTGSQQGLSAAGGGTVSGGGSHEPVFSQFAREAMEMRQAGASHVPSWGEALRNMENAGVTANDVAFSGYAREEIELQRQQEKQLPQAPTAGGSDVVAWSSHRYFTSINLEGVQKKINELTGGTEFGELVQRVEAGARAAPSVGLLLNIMELHKRLPEASRFPALDLLSRLLAVGRHPYRWLLLLLGDSPGEWYCSPLKFMEECVLGVDRASDAECLVTVRLFLHAAAALDALPASTSITPEQAAVLLQAFTQAPRSFIKKNMNNNMKKSVSALLQNVSLLLAHGAPMFGDEGRLNCTQECVRMASHMLLLEPMSSPVIAEVVATVLTLLQAESTANAAAAVGRGTLLHTMRLLKSGSEQRCRRAADIILRVLEADGS
Protein: LD21269p (Q9VSI1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GrpE protein homolog, mitochondrial
- LD43819p
- Diphthamide biosynthesis 4, isoform A
Sequence:
MWPRFGIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHSFQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLGRGSVLPAKIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIPEDGLYQLEVEVDVDDKDGNVVPLVRLRCM
Protein: 3'-5' exoribonuclease 1 (EC 3.1.13.1) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1) (Q7TMF2)
Organism: Mus musculus (Mouse)
Function: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Binds with high affinity to the 3' side of the stem-loop structure and to the downstream cleavage product (DCP) of histone pre-mRNAs. Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs (By similarity). Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18438418}. Nucleus {ECO:0000269|PubMed:18438418}. Nucleus, nucleolus {ECO:0000269|PubMed:18438418}.
Interaction partners:
- Histone RNA hairpin-binding protein
- Endoribonuclease Dicer
- Heterogeneous nuclear ribonucleoprotein Q
- U7 snRNA-associated Sm-like protein LSm11
- Small nuclear ribonucleoprotein-associated protein B
- Y-box-binding protein 1
- 5'-3' exoribonuclease 1
Sequence:
MEDERGRERGGDAAQQKTPRPECEESRPLSVEKKQRCRLDGKETDGSKFISSNGSDFSDPVYKEIAMTNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESSAGDSYYDYICIIDFEATCEEGNPAEFLHEIIEFPVVLLNTHTLEIEDTFQQYVRPEVNAQLSEFCIGLTGITQDQVDRADAFPQVLKKVIEWMKSKELGTKYKYCILTDGSWDMSKFLSIQCRLSRLKHPAFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHSGLDDSKNIARIAVRMLQDGCELRINEKILGGQLMSVSSSLPVEGAPAPQMPHSRK