wanglab/gogpt-training-data huggingface dataset:
Protein: Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein) (Q8NDH6)
Organism: Homo sapiens (Human)
Interaction partners:
- PRKCA-binding protein
Sequence:
MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIGGFLTEQLNKLVLSDEEASFESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEGEDFEKEFSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGSEPLAHSSRFLPSQLFDLGFHVAGAFNNWVSQEESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLDPLSNPDAIGHSDDELLNA
Protein: Rho GTPase-activating protein 20 (RA and RhoGAP domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20) (Q6REY9)
Organism: Rattus norvegicus (Rat)
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Interaction partners:
Sequence:
MEAMSPQQDALGAQPGRSSSLTGMSRIAGGPGTKKKMKTLAERRRSAPSLILDKALQKRPSTRDSHSASIDTCAFLSSFMCSSRTLLIDGPVELKRGLQRQERHLFLFNDLFVSAKIKYNNNFKIKNKVKLADMWTASCVDEVGEGNTNALKSFVLGWPTVNFVATFSSPEQKDKWLSLLQRYIALEKEKDYPKSIPLKIFAKDIGNCAYFKTISVMNSDTASEVINMSLQMLGITGSERDYQLWVNSGKEAAPYPLIGHEYPYGIKMSHLRDTALLTQGSKDSASPSQLQEPFLMEQLPREMQCQFILKPTRLATAQQLSDSSHKTYKRRRSIINWAFWRGSSTHLDNLPVSPTSPMPGQLFGVSLPDICENDNLPKPILDMLSFLNQKGPLTKGIFRQSANMKSCRELKEKLNSGIEVHLDCESIFVIASVLKDFLRNIPESIFSSDLYDHWVCVMDQGNDEEKINTIQRLLDQLPRANVVFLRYLFGVLHNIEQHSLSNQMTAFNLAVCIAPSILWPPASSSPELENEFTKKVSLLIQFLIENCCRIFGEEITSLLGELSERSDREHTPDTSCFQLNDSSYDSLENELNEDADAPCSDLVKRLGQGSRSMDSVLTLSDYDLEPPEAEGLLTLSNFDLDQSKEEHIRTKQPLETKPVSVFVAYRKVSLGEHTRAPDGPGTPSCLPATASDARKVFRRHRRSSEPSIDYLDAKLSYLREFYQKKLRKSSCDAVLSRKDEDYLKQTQPQKKGDQRCFKQSSVTGTDVSKRNTANENIKKKSLSGHEGIQETPFTKSKPVAISVASYMSSQDHSWEQPFEADACRFSPPHIADAQKSSRAHRRCSEPSIDDQNYKLSYLRGVYSKKQSKTSCEAGLLHGEEDYLKRHKSLQMEGQKLINQSLVMGIEVGKSSSSTNQSTEKVLPPRLNLCPRASYSSLSSPGTSPSGSSVSSQDSAFSQISEHSVFTPTETSSPIDCTFRAQRKQEELSSDCDSPSLVSGMPGPSTGQASSHLAYLRKGTTEQLPQMHSVTLHPSTWLRSGLVTLKNWSLKKKTKAARPEDRKDCSLKEPLELPACAAGTPEADSLQESQEDIHLGVDEGAGQTACGLSSYACQDSEQHASSPFCLAGSRLTLGMKLHEGEESGGQYPCDNPWEGAPSGLETSEDAANTGVEPATVCNDGDRH
Protein: Heterogeneous nuclear ribonucleoprotein D (H0Y8G5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
SRQDFFPPVVGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSQGYGGYGGYDYTGYNNYY
Protein: Myo-inositol transporter 2 (P30606)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Minor transporter for myo-inositol.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16233524}; Multi-pass membrane protein {ECO:0000269|PubMed:16233524}.
Interaction partners:
- Myo-inositol transporter 1
Sequence:
MKNSTAASSRWTKSRLSHFFPSYTNSSGMGAASTDQSSTQGEELHHRKHCEEDNDGQKPKKSPVSTSTMQIKSRQDEDEDDGRIVIKPVNDEDDTSVIITFNQSISPFIITLTFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKELITAATSLGALITSVGAGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDGFSSWGIVIIVFIIVYAAFYALGIGTVPWQQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTIFCYFCYPELSGLELEEVQTILKDGFNIKASKALAKKRKQQVAEGAAHHKLKFEPTQEIVES
Protein: Putative tenascin-XA (TN-XA) (Q16473)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEDKNGAPHGAPHSDSPLGFSHAAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGRARTQKLQFLTVPHSCVH
Protein: Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19) (Q9DAM5)
Organism: Mus musculus (Mouse)
Function: Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.
Subcellular location: Mitochondrion membrane {ECO:0000250|UniProtKB:Q9HC21}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Thiamine transporter 2
- Ubiquitin-like protein FUBI
- Thiamine pyrophosphokinase 1
- Large ribosomal subunit protein eL14
Sequence:
MVGYDAKADVRSNSKLEVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMKAALSTGFMFFWYELFCNLFHCIRREDR
Protein: FERM domain-containing protein 8 (Band4.1 inhibitor LRP interactor) (Bili) (iRhom tail-associated protein) (iTAP) (Q9BZ67)
Organism: Homo sapiens (Human)
Function: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface. Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:19572019, ECO:0000269|PubMed:29897333}. Cell membrane {ECO:0000269|PubMed:19572019, ECO:0000269|PubMed:29897333}.
Interaction partners:
- Inactive rhomboid protein 2
Sequence:
MDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQPGDSLEQG
Protein: NADH-ubiquinone oxidoreductase chain 4 (EC 7.1.1.2) (NADH dehydrogenase subunit 4) (P03905)
Organism: Homo sapiens (Human)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03910}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- NADH dehydrogenase 1 beta subcomplex subunit 3
- Cytochrome b
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- Acyl carrier protein, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- Cytochrome c oxidase subunit 1
- NADH-ubiquinone oxidoreductase chain 6
- NADH-ubiquinone oxidoreductase chain 3
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase 1 subunit C2
Sequence:
MLKLIVPTIMLLPLTWLSKKHMIWINTTTHSLIISIIPLLFFNQINNNLFSCSPTFSSDPLTTPLLMLTTWLLPLTIMASQRHLSSEPLSRKKLYLSMLISLQISLIMTFTATELIMFYIFFETTLIPTLAIITRWGNQPERLNAGTYFLFYTLVGSLPLLIALIYTHNTLGSLNILLLTLTAQELSNSWANNLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLTLILNPLTKHMAYPFLVLSLWGMIMTSSICLRQTDLKSLIAYSSISHMALVVTAILIQTPWSFTGAVILMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMAFWWLLASLANLALPPTINLLGELSVLVTTFSWSNITLLLTGLNMLVTALYSLYMFTTTQWGSLTHHINNMKPSFTRENTLMFMHLSPILLLSLNPDIITGFSS
Protein: Probable WRKY transcription factor 24 (WRKY DNA-binding protein 24) (Q9FFS3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MDREDINPMLSRLDVENNNTFSSFVDKTLMMMPPSTFSGEVEPSSSSSWYPESFHVHAPPLPPENDQIGEKGKELKEKRSRKVPRIAFHTRSDDDVLDDGYRWRKYGQKSVKHNAHPRSYYRCTYHTCNVKKQVQRLAKDPNVVVTTYEGVHNHPCEKLMETLNPLLRQLQFLSSFSNL
Protein: Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (Q15247)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MMGRTHGVHAEPTTFGLKMARFHASATRAIERFDRVAAEVETGKLSGAVGTFANVPPYVEAVAMKELGLTPQPIGSQVLPRDLHADYVQTIALIGTQMEELATEIRSLQRSEIHEVEEGFAKGQKGSSAMPHKRNPIGNENITGLARVLRGYAVTALEDVTLWHERDISHSSAERIILPDATTTLDYMLNRQTGILKNLGVFPEKMRHNMDRTYGLIYSQRLLLSLIDAGLSREQAYDTVQPLTARSWDEQLMFRDLVDADPTITAHLTKAQIDDAFDYHYHLRHVDEIFKRVGLA
Protein: 1,3-beta-glucanosyltransferase (EC 2.4.1.-) (Q6FUR4)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Cell envelope {ECO:0000256|ARBA:ARBA00004196}. Cell membrane {ECO:0000256|RuleBase:RU361209}; Lipid-anchor, GPI-anchor {ECO:0000256|RuleBase:RU361209}. Membrane {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004589}.
Interaction partners:
Sequence:
MVSVKQLFAVALASTVFAADSKNGSTPVIEIKGNAFFDSSSNERFYIRGVDYQPGGSSNLTDPLADKEICSRDIPVFKDLGINTIRVYTVDNSQDHSECMQMLQDAGIYLILDVNTPDSSISRHNPSCSYNADYLQNIFATVDEFAKYDNVLGFFAGNEVINMVNNTATATYVKAVVRDMKKYLKARNYRQIPVGYSAADIASNRQLTAEYFNCGDDADARIDMFGVNDYSWCGDSSFVVSGYKTKVDLYKGYSVPIFLSEFGCNQVPGARPFTEIKSIYSTQMSSVFSGGLVYEYSNETNNYGLVQIDSPTNVTKLQDFANLKSEYASVSNPQGDGGYSESNQHSTCPPYQEGIWEANNTLPEMPSAASVYFESGAGQPFGTGIRTQDSCGKDDDDIENQSDDDNSNANSTDTSSSSSMANSSSSSTQSSSSATTLSTSASSTSASSSSSKAKKAKNGAAALEIPAVFRALFEVANFVL
Protein: Uncharacterized protein (Q3TR19)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
FTKEGVWKNPILLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYITCLCSMLPSEEAIQEIAKVDCKDVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDDGKEDK
Protein: Melanoma-associated antigen 10 (Cancer/testis antigen 1.10) (CT1.10) (MAGE-10 antigen) (P43363)
Organism: Homo sapiens (Human)
Function: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Subcellular location: Nucleus {ECO:0000269|PubMed:21710496}.
Interaction partners:
- Melanoma-associated antigen 4
- Cancer/testis antigen 1
- Cancer/testis antigen 2
- Circadian clock protein PASD1
Sequence:
MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE
Protein: Protein TFG (C9JUE0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQS
Protein: L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27) (O51114)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Catalyzes the conversion of lactate to pyruvate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00488}.
Interaction partners:
- Pyruvate kinase
- Glyceraldehyde-3-phosphate dehydrogenase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Acyl carrier protein
- Acetate kinase
- Glycerol-3-phosphate dehydrogenase
- V-type ATPase, subunit K
- Glucose-6-phosphate 1-dehydrogenase
- Elongation factor Tu
Sequence:
MLKSNKVVLIGAGGVGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLKKNINVLFGTYKDCANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVDIMTYVTMKYSKFPIHKVIGTGTILDTSRLRYFLSDHFNVNTQNIHSYIMGEHGDSSFATWDETKIAMKPLSEYLAEGKITELELDEIHKKVVNAAYEVIKLKGATYYAIGLGIKNIVNAIIGDQNVILPISSYINGQYGGLIKDIYIGAPAIVCKEGVKEVLNFKISPKELDKFNSSANQLKSYIDKMEF
Protein: Apoptosis-stimulating of p53 protein 2a isoform X1 (Tumor protein p53-binding protein, 2a) (F1R419)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Cellular tumor antigen p53
- Junction mediating and regulatory protein, p53 cofactor.
Sequence:
MMPMFLTVYLSNNDQHFSEVPITAETVCADVLQLCREPGENSSCYLSEVWRGSERVVGENEKMMDLLLQWGQQRPEVRFFLRHGRAASQPSDSRTQKRNGVKKPADRRLENGVNGPWMDMTLAELQEMASRQQRQIDSQQQLLSTKEQRLRYLQQQEQRQAQSSSEQKKLLQLRETLEQQEAQLKMVRALKGQVEQKRLSNGKLVEQVEQMNNLLHQKQKELVVAVAKVEELSKQLETLKSGQMDAMNSNHSSVAELDRLYRELQMRKNLNVEQNAKLQQQRENLNKRNQEVANMDKRVSELRERLWKKKAALQQKENLPLPPDGQAPPQTPGSRVAAVGPYIQSSTMPRGPDRQDLPIKHNYPEFTATAGHQDRSAQPGAGLHSGKASSKLANWSLANAKSGNNHVTSSLPRMVSQASKSQDNTDVQKRDPRVRPVSMFESTDLPAAALRKNQSSEDLVRDAQSAVKTIVKVPPPVPSKPKQANFPSGGLMGLGKNTGTYPGKSASPQPPAGPQTGTLPSKLEAPPAATVHPFSPDPPGAKDTGGQMLLKPQTVTASSIYSMYTQQPSSGKATQQSIQGALSRAQTRTGHFISVYGKPVTSAGQPSQTPHPENPYLDPPSVSETLTDHSPAEPISETPETERIPRPLSPTKLLPFISNPYRHQSDLDLEALRKKLYNAPRPLKKRSSITEPEGPGGPNIQKLLYQKTTLAAMETVSPPGEEEKETLAKPQGYDAETPEVPEETLPEFPIAPEVEAEDVPPPPPPHPAPKIDASIIIPPPQPESPPPPPPPDSFMEDFPPYPPPPYPSSAEQDNPDDTFNMKPPEVTGQVPFPPGKRTNLRKSGSERIDHSMRVRFNPLALLLDSSLEGEFDLVQRVIYEVEDPSQPNDEGITALHNAVCAGHTEIVKFLVQYGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNRGVVYGLWDYEAAQEDECSFREGDCMSVIRREDELETDWWWVRCGGAEGYVPRNLLGLYPRIKLRQRSLA
Protein: Probable eukaryotic translation initiation factor 4H (J9VI89)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Probable translation initiation factor.
Subcellular location: Cytoplasm, P-body {ECO:0000269|PubMed:27611567}. Note=Localizes to P-bodies during response to heat stress. {ECO:0000269|PubMed:27611567}.
Interaction partners:
Sequence:
MAPKKKGQKMALHEFFEEAATSGTSWADDDFDLPTAPAAREESGSGLKRGDPGYFESLPDRGSRQATFAGAPVQREELPLPTVPPFTAFIGNLSFEPDVEDEVRAFFNDLDPVSVRIVKDPQGKPKGFGYAEFKTQDGLKQALDRSMSQLQGRTIRVNVAEAPSTSRHPPSAAEEASQWRRSTPLASRESSSQPSRRTGGPSEPAADLDWSVARGAKFTPSAPAAPLSGVRRDSSGPGHTREPRDPGVSDTADQWRSNKPLAEKVDRDVPPHQAGVAPPIVSPSLADTEQTWSRGTKLRTPTTTSRQSSADSTPSSGAPQERRKLNLKPRTAGSPSATANATPAAPASGIFGAAKPIDSAAREKAAEEKLAQREGERRKAREEAEKQKAAAGDKPVEGEKLGWREEKLRSIKAAQDKVAGKPTTAPATTTNTGAGRKGSADRAKKDEQGFEQVQPSRKSSQTGATSENKPKKDYSTRPQFSFAAAAGAIRNDLVEDKDEEEVTKGVEEVKI
Protein: TLE family member 3, transcriptional corepressor (H0YKN8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPPPPPLSCLRGLQAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISITSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY
Protein: TCP pilus virulence regulatory protein (P0C6D6)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Function: Probable regulatory protein for the tcp operon.
Subcellular location: Cytoplasm.
Interaction partners:
- Prepilin leader peptidase/N-methyltransferase
- Accessory colonization factor AcfC
- Accessory colonization factor AcfB
- Pyruvate-flavoredoxin oxidoreductase
- Glutamate synthase large chain
- Glutamate synthase large chain
- RDD domain-containing protein
- DNA-directed RNA polymerase subunit alpha
- TagE protein
- 3,4-dihydroxy-2-butanone 4-phosphate synthase
Sequence:
MIGKKSFQTNVYRMSKFDTYIFNNLYINDYKMFWIDSGIAKLIDKNCLVSYEINSSSIILLKKNSIQRFSLTSLSDENINVSVITISDSFIRSLKSYILGDLMIRNLYSENKDLLLWNCEHNDIAVLSEVVNGFREINYSDEFLKVFFSGFFSKVEKKYNSIFITDDLDAMEKISCLVKSDITRNWRWADICGELRTNRMILKKELESRGVKFRELINSIRISYSISLMKTGEFKIKQIAYQSGFASVSYFSTVFKSTMNVAPSEYLFMLTGVAEK
Protein: Transporter protein, putative (Q57YC1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAKRREVADDSDVYVLEFQKNYSDTTRQSLIVSDEVPDSTLLWRNMVMFTLLKIIGSYDSGAFSAAVGAENGIADEWGLTNLEQGALSASVFLGCMVGCPLAGHLFSQYSAKIVLIRVLVLHIFFTFCFATVTVYVISMVSRFLIGVTLSFIFVYVPVWVDDFAPRDRQSVWMALHNAGVPVGVLGGYLCGAILPSYTRISWEWAFYSKCIFTVPVIVYFLRVDHRSVDRNSSRKSNVQGSLGIGHGGNGLPTNGTESAVRRGNENVFDRSSGARNLVSSACDAVLHIWKTAAVLLGNIEYTCSVLAMCSLYFVVSGLQNFMTQYLHAEPFNASMKTIMVGFGTAIVASPIGGVITGGVLLDRLGGYQQNTRRVMIFTTAWGAGAAFFSVLCIFAGSTSALLVLMSLMLFCGGAVVPSGSGRVMASLPDTQRPAGAALAQMVYNLVGNFSGPLVCGSIAQWMGDLKYGIRAVFCCSVIGLVPMVILLFAADRHPSGVCAMSSCGPVSTVVEERLEVKSSGVVVENGNDDTVDAK
Protein: Plasminogen activator inhibitor 1 (Endothelial plasminogen activator inhibitor) (Serpin E1) (F1QRB8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Vitronectin b
- Plasminogen activator
- Vitronectin a.
- Plasminogen
- Type-1 angiotensin II receptor
- trypsin
- Type-1 angiotensin II receptor
- Matrix metallopeptidase 9.
- CCN family member 2
- Mothers against decapentaplegic homolog 2
Sequence:
MQSLSVLLIFALCASSLCNLIQDKQTDFGLQVFAEAVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSLQERGMPKLQRLLQRDLASEDGVEVASGVMVDRKIILEKVFRRSLSKAFQSVPHQIDFSQPEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKTPFDPRNTREQLFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLLVTPFEKDVPLSALNKELSSSRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGLGDIFSQSRADFSRITTEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVIYSRMAVEEITLDRPFFFLIQHKPTGALLFSGQLTQPQEY
Protein: Boca/MESD chaperone for YWTD beta-propeller-EGF (Q8IG33)
Organism: Caenorhabditis elegans
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
- Major facilitator superfamily
- Coelomocyte uptake defective protein 15
- Peroxin/Ferlin domain-containing protein
- Copine family protein 2
- Chloride channel protein
Sequence:
MKWRTVFIFLLAAHIGLANVKQKKKDLSSYTDAELEKLYEEWEENDEDELEEDEKPEHKRKPPQLDLESMKAKAKDPEDLLMMSKKGQTLMLFVGVVDPSQPDRSDIRPFTEKWTQIWQSQLYNNHVDLQVFVIDDNRAIFMFKNGEQAFEAKKFLLKQEFVSEVTIEGQSFDGPAKKFKTGKKEL
Protein: Ectoine hydrolase (EC 3.5.4.44) (E1V7W1)
Organism: Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)
Function: Involved in the degradation of ectoine, which allows H.elongata to utilize ectoine as both a carbon and a nitrogen source for growth. Catalyzes the hydrolysis of ectoine to N-acetyl-L-2,4-diaminobutyric acid (N-Ac-DABA). It can produce both isoforms N-gamma-acetyl-L-2,4-diaminobutyric acid (N-gamma-Ac-DABA) and N-alpha-acetyl-L-2,4-diaminobutyric acid (-Nalpha-Ac-DABA), however N-alpha-Ac-DABA is the essential substrate for the subsequent catabolic enzyme DoeB.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20849449}.
Interaction partners:
- N-alpha-acetyl-L-2,4-diaminobutyric acid deacetylase
- Ectoine dioxygenase
- Transcriptional regulatory protein DoeX
- L-ectoine synthase
- Aspartate-semialdehyde dehydrogenase
- Diaminobutyrate--2-oxoglutarate transaminase
- OCD family protein EutC
- L-2,4-diaminobutyric acid acetyltransferase
- L-threonine dehydratase family protein EutB
Sequence:
MIQVSLPFTREEYAGRLWKVRTEMASRGIDVLVISDPSNMAWLTGYDGWSFYVHQCVLLGLEGEPVWYGRRMDANGALRTCWMDPDNITYYPDHYVQNPDMHPMDYLAQTILPDRGWHEGVVGMEMDNYYFSAKAYQCLLRELPHARFADANSLVNWCRAIKSPQEIEYMRVAGKIVAGMHSRILEVIEPGLPKSKLVSEIYRVGIEGWTSPEGKVFGGDYPAIVPMLPTGKDAAAPHLTWDDSPFREGEGTFFEIAGVYKRYHAPMSRTVYLGRPPSEFVRAESALLEGIENGLEVAKPGNRTADIAMALGAAMDKYGFDRGGARCGYPIGISYPPDWGERTMSLRPSDETILEPGMTFHFMPGLWVEDWGLEITESILITESGCETLADFPRQLFVK
Protein: GM02713p (Q8T9K5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRQLSHASAVTSPPPAPAAQVAPSAAPLVSSTFLSSSTPQRQMLFDMYAPVGANLTHSINGADLNRSYLEANKSDYSLNDISLWFDQRRSSVQPGQGPGSLPAPLPLPMPLGALLEQQPANGGDGRDTEMVNFKLLLHKVKEIVEDSYSDNAELSAATQNLENVLDSIIKSEEQQRRIST
Protein: Heterogeneous nuclear ribonucleoprotein L (hnRNP L) (P14866)
Organism: Homo sapiens (Human)
Function: Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPK and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:17289661, ECO:0000269|PubMed:2687284, ECO:0000305|PubMed:26051023, ECO:0000305|PubMed:36537238}. Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules. {ECO:0000269|PubMed:17289661}.
Interaction partners:
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Interleukin enhancer-binding factor 3
- Polypyrimidine tract-binding protein 1
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoproteins C1/C2
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoprotein H
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoprotein A3
Sequence:
MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
Protein: Palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 12) (DHHC-12) (Zinc finger DHHC domain-containing protein 12) (Zinc finger protein 400) (Q96GR4)
Organism: Homo sapiens (Human)
Function: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering. Thereby, indirectly regulates GABAergic synaptic transmission.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8VC90}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16647879}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAPWALLSPGVLVRTGHTVLTWGITLVLFLHDTELRQWEEQGELLLPLTFLLLVLGSLLLYLAVSLMDPGYVNVQPQPQEELKEEQTAMVPPAIPLRRCRYCLVLQPLRARHCRECRRCVRRYDHHCPWMENCVGERNHPLFVVYLALQLVVLLWGLYLAWSGLRFFQPWGQWLRSSGLLFATFLLLSLFSLVASLLLVSHLYLVASNTTTWEFISSHRIAYLRQRPSNPFDRGLTRNLAHFFCGWPSGSWETLWAEEEEEGSSPAV
Protein: Tubulin polymerization-promoting protein family member 2 (E7FA56)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Anoctamin
Sequence:
MAEGSGEISLGEVEMAFRKFAVHGDTKATGKEMNGKNFVKLCKDCKVIDGKNVTSTDVDIIFSKVKVKSARVITFEQFTQAMGELATKRFKGKSQEEAVQLLYGLIAGKEPTNIGVTKVAKASAVDRLTDTSKYTGSHKERFDESGKGKGREGRADIPDTSGYVSAYKGQGSYDSKVKEDE