wanglab/gogpt-training-data huggingface dataset:
Protein: Transcription factor MYB10 (Myb-related protein 10) (AtMYB10) (Q9LTV4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in metal ions homeostasis, including iron ions (Fe) acquisition, via the regulation of NAS4 and NAS2 genes expression. Necessary for plant survival in alkaline soil where iron availability is greatly restricted. Triggers tolerance to nickel (Ni) and zinc (Zn) ions.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:24278034}.
Interaction partners:
- Transcription factor bHLH3
- Anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase
- Transcription factor SCREAM2
- Probable nicotianamine synthase 4
- Dihydroflavonol 4-reductase
- Fe
- Scopoletin 8-hydroxylase
- Ferric reduction oxidase 2
- Naringenin,2-oxoglutarate 3-dioxygenase
- Transcription factor bHLH47
Sequence:
MGNRRAPCCDKSQVKRGPWSDEESERLRSFILKNGHQNWRSLPKLAGLMRCGKSCRLRWINYLRPGLKRGNFTKEEEDTIIHLHQAYGNKWSKIASNFPGRTDNEIKNVWNTHLKKRLVKRSISSSSSDVTNHSVSSTSSSSSSISSVLQDVIIKSERPNQEEEFGEILVEQMACGFEVDAPQSLECLFDDSQVPPPISKPDSLQTHGKSSDHEFWSRLIEPGFDDYNEWLIFLDNQTC
Protein: Frizzled class receptor 3 (M0RCN5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Protein Wnt-5a
- Protein Wnt
- Protein Wnt-4
- Protein Wnt
- Protein Wnt
- LDL receptor related protein 5
- Protein Wnt
- Receptor-like tyrosine kinase.
- Low-density lipoprotein receptor-related protein
- Receptor tyrosine kinase-like orphan receptor 2
Sequence:
MAVSWIVFYLWLLTVFLGQIGGHSLFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCDEPYPRLVDLNLVGDPTEGAPVAVQRDYGFWCPRELKIDPDLGYSFLHVRDCSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDRVACNASSPAQYKASTVTQGSHNKACTMLFMVLYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQMSRPDLILFLMKYLMALIVGIPSIFWVGSKKTCFEWASFFHGRKKKETVNESRQVLQEPDFAQSLLRDPNTPIIRKSRGTSTQGTSTHASSTQLAMVDDQRSKAGSVHSKVSSYHGSLHRSRDGRYTPCSYRRDGGETTSRQHVTADRSLQAQ
Protein: EVE1 (Even-skipped-like1) (Q90265)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MPEDRELPVSTVAHADSDQGEEECPRISLLNGIDQSRRHRTAFTREQLTRLEQEYCKESYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRHSLHWPNPLDPNLCAFMVGQTAAALPYPLLPRLPIHLYSHLGMGSLSGFSTPYSATTRPVDTLHLPPSTYPWLGGLPQPALYSPVQTMHHPVGCHCPQCLQWRPDHLLKPRGGARTGLQPQTFGSASG
Protein: Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3) (O95076)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator with a possible role in patterning of mesoderm during development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Sodium-dependent neutral amino acid transporter SLC6A17
- Ubiquitin-like protein 4B
- mRNA turnover protein 4 homolog
- RNA-binding protein 15
Sequence:
MDPEHCAPFRVGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT
Protein: Ig-like domain-containing protein (Q95Q96)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MWHYRLTTILLIISIIHSIRAKRKLKEQEIIQRILKDYDWRVRPRGMNATWPDTGGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAYERYEESGDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLRQSLPSFELQDVVTDYCTSLTNTGEYSCLRTRMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINAKLPPVSYTKAIDVWIGVCLAFIFGALLEFALVNYAARKDMTQVSQRIRQMKQLPTEGYRPLSASQGRSSFCCRIFVRRYKERSKRIDVVSRLVFPIGYACFNVLYWAVYLM
Protein: TATA-box binding protein associated factor 15 (A0A075B7D9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSARPRASHLAASYLSFPILEVELGLPDSPIHQQVFGNIFVGADSQSSPIQRNGVYLGVILEVTVSLGVSSKVILPMEIQAAKAMDKHHKAILAMGKRLIPLMDRTTAVTPVMDKVSQVIHSPMVVMRIKSRAHIASNHIITRDSSKTWNHQEAKVEEHLPMTSQTMVNKIHMTSSQAMINIKAHMMSSQIMISSMIPIVKTSSPIIHKGKTTATTHKMTVVM
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (CPH) (Cyclosporin A-binding protein) (Rotamase) (P22011)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular location: Cytoplasm.
Interaction partners:
- Nucleoporin NSP1
- Ran GTPase-binding protein
- Enolase 1
- SIR4-interacting protein SIF2
- Uncharacterized protein
- Snt1p
- GTP-binding nuclear protein
- Nucleoporin
- Fructose-bisphosphate aldolase
- Pre-mRNA-processing factor 17
Sequence:
MSTVYFDVSADGQKLGKITFKLYDDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPQFMLQGGDFTNFNGTGGKSIYGTKFADENFVKRHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVTDGLDIVKKIESFGSGSGATSKKIVIEESGQL
Protein: Cysteine/Histidine-rich C1 domain family protein (F3H7.4 protein) (Q9ZSB4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDSELELISLISQLISLPKILDSKWNSVTHSEIISLIAQIISLVSSMDLHSQPKPESEFMSLVTQAISLFDSMDLNPELSPLSELISLLSQIISTDSDSDSNRKVEWDLDRPLCETLFGQPEPELVSLIYQIFSLVSSINSKSEKFISLCPQLLVELEKGNFHVSEYFQPWGKWYCLPGNWVKFKFTGEDATYFGCKGCNGKNHEEYEQAPDEIKHHLHRKHSLQLVFFSEGKERKCYCCDDDLEKVIYCCVSCDYAMNMACAKKPPVLSIDHPKWHEHTLVLFPRRAFLTCNLCGLADARSPLYMCPPCDFVVHLRCIDLPRVIRISRHHHRISFTPSFDQERLSCGVCQKNIDNDYGGYSCIKEGCFYAAHSKCATQRNVWDGKELEGEQEEEIKEVEPFVKISDGIIQHFSHQHHHLRLDDNINRDYDENKECQACIRPIYFGNFYSCMQCEFILHEECANLFRQIYHPIHPHMLSLGYDNIVDHEVMCAAYPSLWTAGFFYECGKEGCDFKLPVQFATTSEPLVHESHMHPLFLTSKPEEDPRRCSVCKESRYARTNETFNCIECDFALCFVCATLPQKVRYKHDKHVLTLFYGNETSTITYWCEICEGTIDPTKRFYVCDEYCCLTLHIKCLLGWDLYMKHGSSSFYLEKTVDVLSNNHHMTRPICCYCEKRCPYKICLEWSGSIYCSSDCIFTFLIF
Protein: Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein) (P20111)
Organism: Gallus gallus (Chicken)
Function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity).
Subcellular location: Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}.
Interaction partners:
- Myozenin 1.
- Troponin T, cardiac muscle isoforms
- PH_9 domain-containing protein.
- Uncharacterized protein.
- Myosin-binding protein C, cardiac-type
- Troponin C, skeletal muscle
- Troponin T, fast skeletal muscle isoforms
- Troponin I, fast skeletal muscle
- Tropomyosin alpha-1 chain
- Myosin light chain 1, skeletal muscle isoform
Sequence:
MNSMNQIETNMQYTYNYEEDEYMTQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHLSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHEQWAYGKEQILLQKDYESASLTEVRAMLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNDRCQKICDQWDSLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLISAHDQFKATLPEADGERQAILSIQNEVEKVIQSYSMRISASNPYSTVTVEEIRTKWEKVKQLVPQRDQSLQEELARQHANERLRRQFAAQANVIGPWIQTKMEEIARSSIEMTGPLEDQMNQLKQYEQNIINYKHNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNDFRASFNHFDRRKNGLMDHDDFRACLISMGYDLGEAEFARIMSLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILADELRRELPPEQAQYCIKRMPQYTGPGSVPGALDYTSFSSALYGESDL
Protein: Down syndrome cell adhesion molecule 1, isoform BX (A0A0B4K823)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Netrin-B
- Netrin receptor unc-5
- non-specific serine/threonine protein kinase
- Dreadlocks, isoform B
- Sorting nexin
- Protein slit
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVSQHYEEDIHKAFVIRGNSAILKCDIPSFVADFVNVISWHSDEKENFYPGTEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGSVSPQLSGNGNQEHITLTRVPKMGSVTLMCPAQAYPVPFFRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVLPQIVPFAYEDLINMGDSIDLFCQIQKGDRPIKVHWSFERSAGDYGFDQVQPQMRTNRISEKTSMISIPSASPAHTGRDTCIASNKAGTTTYSVDLTVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Protocadherin 7 (A0A0G2JG16)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTSNKYSKQPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVGEAEHMENGRGKHNIHTHNHASEPE
Protein: CENP-A recruiting complex protein mis20 (Eighteen-interacting centromere protein 2) (Kinetochore protein mis20) (O94682)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A. Seems dispensable for proper chromosome segregation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:16823372}. Chromosome, centromere {ECO:0000269|PubMed:24774534, ECO:0000269|PubMed:24789708}. Note=Localizes at the centromeres during interphase, but not in mitosis (PubMed:24774534). {ECO:0000269|PubMed:24774534}.
Interaction partners:
- CENP-A recruiting complex protein mis19
- Histone acetyltransferase type B subunit 2
- Kinetochore protein mis18
- CENP-A histone chaperone scm3
- Uncharacterized serine-rich protein C2F12.03c
- Inner kinetochore subunit mal2
Sequence:
MLEQSESHAFINNAPKEDRIQVKFEQLFESLPLPLRAEEALSKLRHDSARLMILKTSDPTLNMSTYSIEDSPMGFECLKYNLSDNNKLLSQNNYRLPDYLEEDEIVSYTFSKTGPTTSKNKHPSHSNTIRSPPYKVKKESCHTEINNVSNVSTESINVIDASRGYSPYTSVDSLSVSKNRSFISLEESASNQYDAAEAFYFNADSSSPLRKLSPIELPVTPIRRKTPTINPNSELKRLQTFGKLILHKGSRRR
Protein: Rhophilin-1 (GTP-Rho-binding protein 1) (Q61085)
Organism: Mus musculus (Mouse)
Function: Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.
Interaction partners:
- Ropporin-1
- Transforming protein RhoA
- Citron Rho-interacting kinase
- Serine/threonine-protein kinase N1
Sequence:
MILEERPDGQGTGEESSRPQDDGSIRKGYGSFVQNQPGQLQSHRARLHQQISKELRMRTGAENLYRATSNTWVRETVALELSYVNSNLQLLKEELAELSTSVDVDQPEGEGITIPMIPLGLKETKELDWATPLKELISEHFGEDGTSFETEIQELEDLRQATRTPSRDEAGLDLLAAYYSQLCFLDARFFSPSRSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTNHAAEAFQRAAGAFRLLRENFSHAPSPDMSAASLSMLEQLMIAQAQECIFKGLLLPASATPDICPDQLQLAQEAAQVATEYGLVHRAMAQPPVRDYLPASWTNLAHVKAEHFCALAHYHAAMALCESHPAKGELARQEHVFQPSTPHEPLGPTLPQHPEDRRKLAKAHLKRAILGQEEALRLHTLCRVLRKVDLLQVVVTQALRRSLAKYSQLEREDDFFEATEAPDIQPKTHQTPEGPLSVFSTKNRWQLVGPVHMTRGEGSFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQLRSMGEEGVSLQVVSLLPSPEPRGTGPRRAALLWNQRECGFETPMPTRTRPWPILGWSRKNKQGKTGSHPDPCTNRNCVTCP
Protein: Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H) [Cleaved into: Entry protein H*] (P03736)
Organism: Escherichia phage lambda (Bacteriophage lambda)
Function: Serves as a ruler that controls the length of tail by stopping the tail tube polymerization and is probably released from the tail shaft during infection to facilitate DNA translocation into the host cell. Assembles into a multimeric linear form possibly stabilized by the covering tail assembly proteins G and GT. Its C-terminus fixes the tail tip complex (J, I, L, K), thereby forming the tail assembly initiator complex. Tail tube proteins polymerize around tape measure protein, displacing the tail assembly protein G and GT. When the tail reaches the length specified by the tape measure protein, it stops and becomes capped by the tail terminator protein (Probable). Upon tail assembly, tape measure protein is cleaved into a form called H*, that plays a role later during virion entry in a new cell (Probable). Once assembled, the virion is released and can infect new cell by binding to the entry receptor LambB (Probable). After opening of a pore on the external membrane, the entry protein H* protein is probably released in the periplasmic space for successfull DNA injection.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04138, ECO:0000269|PubMed:4476800}. Note=There are 6 copies of entry protein H* per mature phage. {ECO:0000255|HAMAP-Rule:MF_04138, ECO:0000269|PubMed:4476800}.
Interaction partners:
Sequence:
MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTESDAKKTAAVVEQSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKDSFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQAGLTADRMLVLSRAGQAAGLTFNQTSESLSALVKAGVSGEAQIASISQSVARFSSASGVEVDKVAEAFGKLTTDPTSGLTAMARQFHNVSAEQIAYVAQLQRSGDEAGALQAANEAATKGFDDQTRRLKENMGTLETWADRTARAFKSMWDAVLDIGRPDTAQEMLIKAEAAYKKADDIWNLRKDDYFVNDEARARYWDDREKARLALEAARKKAEQQTQQDKNAQQQSDTEASRLKYTEEAQKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSSVKVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDLWKAESQFAVLEEAAQRRQLSAQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFAQQQRAKRAAIDAKSRGLTDRQAEREATEQRLKEQYGDNPLALNNVMSEQKKTWAAEDQLRGNWMAGLKSGWSEWEESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQNWRSFTRSVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMADSRSQASGTFEQNNHVVINNDGTNGQIGPAALKAVYDMARKGARDEIQTQMRDGGLFSGGGR
Protein: RluA pseudouridine synthase 2, isoform E (M9PFI9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MESSKLLRNAQTQHGDASSVDVENIFLHRHMLYTNPTSDGNLHDREDSPECVWCPDDKDGSPAESKDPPISISEEKSETQSKEVLSEKRKASSTDDEGHVKKVKLEANSLKTKRPGFSDERYDETSYYFENGLRKVYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAGKLTVNSEKVPKDYKIKHNDLLANVVHSPSRLCTWTRILWL
Protein: Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7) (Q8BL97)
Organism: Mus musculus (Mouse)
Function: Required for pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q16629}. Cytoplasm {ECO:0000250|UniProtKB:Q16629}.
Interaction partners:
- Serine/arginine-rich splicing factor 3
- Serine/arginine-rich splicing factor 1
- Transformer-2 protein homolog beta
- Serine and arginine-rich splicing factor 11
- Serine/arginine-rich splicing factor 2
- Splicing factor U2AF 65 kDa subunit
- SRSF protein kinase 1
- Serine/arginine-rich splicing factor 9
- Transformer-2 protein homolog alpha
- Nuclear RNA export factor 1
Sequence:
MRSSARGRPLQAATAFFLSLFFFLRRFERGFWLWGGDSETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSVSLRRSRSASLRRSRSGSIIGSRYFQSRSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPHRSASPERMD
Protein: Semaphorin-3E (Semaphorin-H) (Sema H) (P70275)
Organism: Mus musculus (Mouse)
Function: Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation.
Subcellular location: Secreted.
Interaction partners:
- Plexin-D1
- Neuropilin-1
- Plexin-A3
- Neuropilin-2
- Plexin-A1
- Plexin-A4
- Vascular endothelial growth factor receptor 2
- Plexin-C1
Sequence:
MAPAGHILTLLLWGHLLELWTPGHSANPSYPRLRLSHKELLELNRTSIFQSPLGFLDLHTMLLDEYQERLFVGGRDLVYSLNLERVSDGYREIYWPSTAVKVEECIMKGKDANECANYIRVLHHYNRTHLLTCATGAFDPHCAFIRVGHHSEEPLFHLESHRSERGRGRCPFDPNSSFVSTLVGNELFAGLYSDYWGRDSAIFRSMGKLGHIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKMYFFFTEKALEAENNAHTIYTRVGRLCVNDMGGQRILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDVFLLPTRDPKNPVIFGLFNTTSNIFRGHAVCVYHMSSIREAFNGPYAHKEGPEYHWSLYEGKVPYPRPGSCASKVNGGKYGTTKDYPDDAIRFARMHPLMYQPIKPVHKKPILVKTDGKYNLRQLAVDRVEAEDGQYDVLFIGTDTGIVLKVITIYNQETEWMEEVILEELQIFKDPAPIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAWDGISCSRYYPTGAHAKRRFRRQDVRHGNAAQQCFGQQFVGDALDRTEERLAYGIESNSTLLECTPRSLQAKVIWFVQKGRDVRKEEVKTDDRVVKMDLGLLFLRVRKSDAGTYFCQTVEHNFVHTVRKITLEVVEEHKVEGMFHKDHEEERHHKMPCPPLSGMSQGTKPWYKEFLQLIGYSNFQRVEEYCEKVWCTDKKRKKLKMSPSKWKYANPQEKRLRSKAEHFRLPRHTLLS
Protein: Chlorophyll a-b binding protein 2.2, chloroplastic (Photosystem II light harvesting complex gene 2.2) (Protein LIGHT-HARVESTING CHLOROPHYLL B-BINDING 2.2) (Q9S7J7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated (By similarity). Mediates rapid phosphorylation and migration of LHCII-PSII to photosystem I (PSI) after transition to state 2 (red) light conditions, thus leading to the formation of PSI-PSII-LHCII and PSI-LHCII supercomplex to balance the relative excitation of PSI and PSII. Involved in the production of reactive oxygen species (ROS) and stomatal closure upon abscisic acid (ABA) treatment. Required to prevent water loss.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:23995216}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Chlorophyll a-b binding protein 2.1, chloroplastic
- Chlorophyll a-b binding protein CP26, chloroplastic
- Photosystem II CP43 reaction center protein
- Chlorophyll a-b binding protein 3, chloroplastic
- Photosystem I subunit O
- Photosystem I reaction center subunit V, chloroplastic
- Chlorophyll a-b binding protein
- Photosystem II reaction center protein H
- Photosystem I iron-sulfur center
- Chlorophyll a-b binding protein 2.4, chloroplastic
Sequence:
MATSAIQQSSFAGQTALKPSSDLIQKVGVLGGGRVTMRRTVKSTPQSIWYGPDRPKYLGPFSENTPSYLTGEYPGDYGWDTAGLSADPETFAKNRELEVIHSRWAMLGALGCTFPEILSKNGVKFGEAVWFKAGSQIFSEGGLDYLGNPNLIHAQSILAIWAVQVVLMGFIEGYRIGGGPLGEGLDPLYPGGAFDPLNLAEDPEAFSELKVKELKNGRLAMFSMFGFFVQAIVTGKGPIENLFDHLADPVANNAWSYATNFVPGK
Protein: Phosphotransferase (EC 2.7.1.-) (Q5G1T8)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
DFLDYMGMKSARLPLGFTFSFPCHQKSLDAGILVNWTKGFKCTDCEGEDVVELLREGIKRKEEFDPDVVAVVNDTVGTMMTCAYEEPTCEVGLIAGTGSNACYMEEMRNIETVEGNEGRMCVNMEWGAFGDNGCPDDIRTQYDCAVDDNSLNEGKQRYEKMCSGMYLGEIVRNILIDLTKRGFLFRGKISGTLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLDSTCDDSIIVKEVCSTVSLRAAQICGAGMAGVVDKIRENRGLDHLDVTVGVDGTLYKL
Protein: Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (O60725)
Organism: Homo sapiens (Human)
Function: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19158273, ECO:0000269|PubMed:9614111}; Multi-pass membrane protein {ECO:0000269|PubMed:19158273}.
Interaction partners:
- CAAX prenyl protease 2
- CAAX prenyl protease 1 homolog
- GTPase NRas
- GTPase KRas
- GTPase HRas
Sequence:
MAGCAARAPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGTLLSFSQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLSVTGLLMVVFGECLRKAAMFTAGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTVWRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL
Protein: type I protein arginine methyltransferase (EC 2.1.1.319) (H0YDE4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
XAANCIMEVSAWSAAVGGRRLWNFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIK
Protein: Uncharacterized protein (Q38DE3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLGAGTWFIGFGIPAVLAGGFVASRKRLAYQWREELMDPDGGAYPPLTDADMEFIRHVTPPEWPLPEGQLPTAKKVTGLFVSPDVLSGDEGGALLDEVKRWIALYGQKVDLRKVAFAESQAQSEGVDIGFYSDIAIISDHAEDIQLMKAPWETGDRIKHHKMPSSLRYMVNKMQRKFEGLGRLRHVYVEYSPSGRFYHEPKPTKAFDGHDYVVIPLRRDQNATVVTFAPLLRSRCSFVKEVLMRSWTSHDVDVIIPPGSALRVYGSARYEWGWGIRPGNVWFGNYRNSIRHIDAIRTPFYLHNILSSMACRILRPAPSVKESDAALVVLHFDGPRDFDKPRSLLLQPESLIFGRPPTVETYEKWVEEKPTTESVRNEGVFLFMVKNYVEMLRVT
Protein: Carnation, isoform B (A4V4S5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFPHLKGHGQRVNLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLLALKPELHLPREVANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFAHRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAPLTARIVEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMSS