wanglab/gogpt-training-data huggingface dataset:
Protein: Kin of IRRE-like protein 1b precursor (Kirre-like nephrin family adhesion molecule 1b) (Si:ch211-195h23.2 protein) (B3DHL7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- NPHS1 adhesion molecule, nephrin.
- Spermine synthase.
- Tectorin alpha.
Sequence:
MGFSMTCLWIVTLAIISVHRVFSGPRFSQEPADQSVVIGERVVLSCVVFNYTGIVQWTKDGLALGIGEDLRAWPRYRVLRIMDVGQYNLEITSADLTDDSLYECQATEAALRSRRAKLTVLIPPDGPVIEGSPEILLTAGTSFNLTCVSRGAKPMSTIEWYKDGIIVEGAHTSTEVLSDRKRVTTKSFLEIQPMDTDTGRNFTCVASNLAAPLGKRSTVTLNIHHPPTVILSIEPRSVLEGERVKFTCQATANPPIMGYRWAKGGVILDGARESVFETTADHSFFTEPVSCLVFNAVGSTNVSILVDVHFGPILVVEPRPVTVDVDSDVTLNCKWSGNPPLTLTWTKKGSSMVLSNSNQLFLKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPIQYAVRGEKGEIKCYIASTPPPDKIVWAWKENVWEKERGTLLERYTVEQSRPATQGGAVLSTLTINNVMEADFQSTYNCTAWNAFGPGTMIITLEETDIVPVGVIAGGSVGSSILLLLLLFALIFYLYRQRKSSRRGVTLKPDIKVETVNKETNLEEEAASASTATRMFLPSVSLSPSTQPFKDDMDLKQDLQTETLEPKVEEYEAKDPTNGYYNVRATTHDEVRSSTRSLLYQEFRAPNPASVSASTGGPANIHPAPTGRYEARPTSRMAHNTYAHFNTIARASQIQPPANPVSKTTDYPAERGLLESTNPLAFDSYAYSTTPQYRLGFAPPLEAGPAYEMYPTGQGVGTSQDANVGKYPSSAQFPYSTPPTEYSQRHTQRMQTHV
Protein: Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (P34113)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
Subcellular location: Cytoplasm.
Interaction partners:
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein eL38
- Small ribosomal subunit protein eS4
- Small ribosomal subunit protein eS24
- Small ribosomal subunit protein eS26
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein uL22
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS11
- Large ribosomal subunit protein uL23
Sequence:
MSHRKFEAPRHGNLGFRPRKRAARHQGKVKSFPKDDRTQKVHLTAFMGYKAGMTHVVRDLEKPGSKMHKKEIVEAVTIIECPPMYIVGLVGYVETAQGLKTYKTVWAQHLSDNFRRRLYKNWYKSKSKKAFTKYVKQYETEEGKKSIEASLQAIKKRCSVVRVIAHTQVHKLKLTQKKAHVLEIQVNGGSIVEKVNFAVANFEKTVNVTGVFAENELIDVIGVTKGKGFNGVIKRWGVRKLPRKTHKGLRKVACIGAWHPSRVSTTVPRAGQLGYHHRVERNKKIYRIGQAQPEDGKQISTGKTEFDLTEKTINPMGGFAHYGMVKHEFLMLKGCVAGPRKRALTLRKSITTQTGRAALEKITLKFIDTSSKFGHGLHQTAEDKTKYFGVKKSRSTKA
Protein: AT5g40660/MNF13_180 (ATP12 protein-like protein) (Q94BY8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- ATP synthase F1 complex assembly factor
Sequence:
MAAMLIGRAFKSARNSNLAIRARSLCTTSAARQPDSDTQPSESSSSFTFEKENEKPILVKAPNSRRKNESDSVTMPTSFMTGSIVGKRFYKKVTTREADDGNGWTVMLDYRTLKTPSKRPLKLRSLALAKAIAAEWEYQLTEGIRPFTMPLMRLACTALERVPLTRSKIIEHLSRKIHQDLVFFRAPEDNDLTSDVHDIQVESIDPLLEWIESEFRVKPKVYSSIFGGKQDDKLVKAVEELLKKTNDGELASIDALQASAHSIVIALGIFCGKLQIDDAIKLIRLEEDLQVDKWGLVEGGHDIDVADLKVQISSATVFLALSREN
Protein: Zinc finger protein ztf-2 (Q19418)
Organism: Caenorhabditis elegans
Function: Transcription factor. Represses gene expression, probably via binding to DNA consensus sequence 5'-[AT][CT]TTCC[AC][AG]-3' in promoter regions. May play a role in pharynx morphogenesis.
Interaction partners:
- EB domain-containing protein
- T-box transcription factor tbx-8
- C2H2-type domain-containing protein
- Helix-loop-helix protein 6
Sequence:
MNCESLLTALDVSTLLSTLSSPEKEHRRKRRRGEVANPSNTLDALVARKADDQPFEKRYLSEQEAIEGPDDEIEMKKMELDPDVSTRTCSTCGYQGKWVSEMIRHKRVHTSERPFKCRYCSRTSKWKADLIRHVAKTHGIRVVSKYSRSKVFDATNSSMDSSCSSDSDRCIISEKRTVFYRCQLCSFEDERVSVLNSHVSHLHNTSPCVCRCGAKFEDVQGALAHSNGPCSHVDMIYNVMPTYEKASPLSPCRSESSSDSGIQTDPEEEASIITSSLPTPQLGSSPLLLSPTLPVTPSFLPDIQSALLSLQPNPLMSLYLASLLQSSLLNSPTIPTSFPQIIPTTILTPSQQDEMVDVEM
Protein: Clathrin light chain B (Lcb) (Q6IRU5)
Organism: Mus musculus (Mouse)
Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular location: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Interaction partners:
- Clathrin heavy chain 1
- AP-2 complex subunit beta
- AP-2 complex subunit alpha-1
- AP-2 complex subunit mu
- AP-2 complex subunit sigma
- Cyclin-G-associated kinase
- AP-2 complex subunit alpha-2
- EH domain-containing protein 2
- Adaptin ear-binding coat-associated protein 1
- Huntingtin-interacting protein 1
Sequence:
MAEDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDPGFGAPAASQVASAQPGLASGAGSEDMSTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
Protein: Inactive serine protease 35 (Q8N3Z0)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MENMLLWLIFFTPGWTLIDGSEMEWDFMWHLRKVPRIVSERTFHLTSPAFEADAKMMVNTVCGIECQKELPTPSLSELEDYLSYETVFENGTRTLTRVKVQDLVLEPTQNITTKGVSVRRKRQVYGTDSRFSILDKRFLTNFPFSTAVKLSTGCSGILISPQHVLTAAHCVHDGKDYVKGSKKLRVGLLKMRNKSGGKKRRGSKRSRREASGGDQREGTREHLRERAKGGRRRKKSGRGQRIAEGRPSFQWTRVKNTHIPKGWARGGMGDATLDYDYALLELKRAHKKKYMELGISPTIKKMPGGMIHFSGFDNDRADQLVYRFCSVSDESNDLLYQYCDAESGSTGSGVYLRLKDPDKKNWKRKIIAVYSGHQWVDVHGVQKDYNVAVRITPLKYAQICLWIHGNDANCAYG
Protein: Alpha-internexin (Alpha-Inx) (P23565)
Organism: Rattus norvegicus (Rat)
Function: Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges (By similarity). May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Interaction partners:
- Neurofilament light polypeptide
- Neurofilament medium polypeptide
Sequence:
MSFGSEHYLCSASSYRKVFGDGSRLSARLSGPGASGSFRSQSLSRSNVASTAACSSASSLGLGLAYRRLPASDGLDLSQAAARTNEYKIIRTNEKEQLQGLNDRFAVFIEKVHQLETQNRALEAELAALRQRHAEPSRVGELFQRELRELRAQLEEASSARAQALLERDGLAEEVQRLRARCEEESRGREGAERALKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVAELLATLQASSQAAAEVDVAVAKPDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEYRRQLQARTIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLESDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTSGLSISGLNPLPNPSYLLPPRILSSTTSKVSSAGLSLKKEEEEEEEEEEGASKEVTKKTSKVGESFEETLEETVVSTKKTEKSTIEEITTSSSQKM
Protein: N-formylmaleamate deformylase (EC 3.5.1.106) (Nicotinate degradation protein D) (Q88FY3)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Function: Deformylase that catalyzes the conversion of N-formylmaleamic acid to maleamate in the aerobic nicotinate degradation pathway.
Interaction partners:
- Maleamate amidohydrolase
- 2,5-dihydroxypyridine 5,6-dioxygenase
- Maleate isomerase
- 6-hydroxynicotinate 3-monooxygenase
- Putative metabolite transport protein NicT
- Nicotinate dehydrogenase subunit B
- Electron transfer flavoprotein, alpha subunit
- Nicotinate dehydrogenase subunit A
- NADH dehydrogenase
- Oxidase
Sequence:
MSTFVAGGNVSANGIRQHYLRYGGKGHALILVPGITSPAITWGFVAERLGHYFDTYVLDVRGRGLSSSGPDLDYGTDACAADIPAFAAALGLDSYHLLGHSMGARFAIRAAAQGAPGLQRLVLVDPPVSGPGRRAYPSKLPWYVDSIRQATVGMSGDDMRAFCATWSDEQLALRAEWLHTCYEPAIVRAFDDFHEVDIHQYLPAVRQPALLMVAGRGGVIEPRDIAEMRELKPDIQVAYVDNAGHMIPWDDLDGFFAAFGDFLDHPLV
Protein: SKN-1 Dependent Zygotic transcript (O02297)
Organism: Caenorhabditis elegans
Interaction partners:
- CABIT domain-containing protein
- Ectopic P granules protein 2
Sequence:
MYPQYPAQPAPGVRPIMCPRPLPKFAMGNCPVTRTRTIGVQRFGQYYMFNKHPASPKLVPHKCLQCQARVTEADLYPKYSVVCNKTSTLVIFVHNGITNKIEQYAYSHSTGGFVEVSFPELVYNPSLVTHGNLVVVIKGLKNENIVIERDLRGGIRKQSSHLGPFQAIPPVVVRTLMMQEIEKGIDVTGNPENPDSAVESDYDSEEDDEDEDDEDDLDVDDLNYLDSLPTFKVRICQASQKEVVCVINSCNGNYIKYIYNDHTGNFDFYQGTSKFEVTEDSLVAKYSEFHQGLKKYVFHVHNLESNLMEKYYYQAEFNSLVQTHCNDLIYDPAKITQSHVLAVINRNDLPQPVVEVIVRNLYGKIRKEIPEMYGFIQTPVTVKTFIVQMEEERRKKTKIIYDKVQLAKKKNKEIKLKKKVLEEEEKTEKMMENMTLENSEDQSKKDEATVDAEIRTEESDNPFKRIPVIDAQKRLIDAIFQRQIDCNIEDSEKQRINIDIQRGLKWFQECKEARKRKEAEAAQKTLEQKHRAALLTFRERHDDQ
Protein: SAM and SH3 domain-containing protein 3 (SH3 protein expressed in lymphocytes) (Q8K352)
Organism: Mus musculus (Mouse)
Function: May function as a signaling adapter protein in lymphocytes.
Interaction partners:
- RAS protein activator like-3
- BET1 homolog
- Rho GTPase-activating protein 30
- Lysosomal-associated transmembrane protein 5
Sequence:
MLRRKPSNASDKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVLTPEDSGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMGDTLEEGSASPTSPDCSLDSPGPEKMALAFTEQEEREPPSLSRQTSTGSELCSPGPGSGSFLEESPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIVEKPPVGTWLGLLNGKLGSFKFIYVDVLPEEAVGPVRPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRDEAELAGTEEQLQGLSLSGAP
Protein: Rhino (Q49BL4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRNHQRPNLGLVDAPPNDHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAAAKSVGKSKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMNQKKGKNIKKTAGKIKDIENYPKTQMPSTSQVSTDSTEVFDGNPSATTTNMIKSPRIQSLFSDLNLIEPTKDKDVGDTSLKTPPKSRRLIEFPQREDAPLSSKHVSPMLIRKESQPLQSSCTDDSDLGESSSSMSLPTVSSTSSEKSIKVTKSEPKTLGQIMFSSRSSDGGHAASSLGAPKEGDIGLDLSGSDSMDSEVESMRRCPRRKRKKTYPNWKFPEITKPFGVNRGLDLDEILHCYQMNDDLFMFVTWKGCSSIDAVHINDIKEAYPLQIIKYFESLRIIVPK
Protein: V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD) (O46563)
Organism: Bos taurus (Bovine)
Function: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes (By similarity).
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000269|PubMed:32764564}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- V-type proton ATPase subunit E 1
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase catalytic subunit A
- Renin receptor
- V-type proton ATPase subunit C 1
- V-type proton ATPase subunit F
- V-type proton ATPase subunit d 1
- V-type proton ATPase subunit S1
- V-type proton ATPase 116 kDa subunit a 1
- Ribonuclease kappa
Sequence:
MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISSEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTLVDDTLQENHQRVSIFFDYAKRSKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVTAETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSVWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSVERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAARLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS
Protein: Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (Q08012)
Organism: Drosophila melanogaster (Fruit fly)
Function: Adapter protein which modulates signaling mediated by several receptor tyrosine kinases such as sev and Ack. Required for proper signaling by sevenless. May act to stimulate the ability of Sos to catalyze Ras1 activation by linking sevenless and Sos in a signaling complex. Required for functional and morphological integrities of the scolopidia, sensory neurons and the antennal mechanosensory and motor center (AMMC) brain neuropil. Required for Ack-dependent suppression of apoptosis in the eye.
Subcellular location: Membrane {ECO:0000269|PubMed:8462098}; Peripheral membrane protein {ECO:0000269|PubMed:8462098}. Synapse {ECO:0000269|PubMed:30610177}. Note=Localizes at the presynaptic terminal. {ECO:0000269|PubMed:30610177}.
Interaction partners:
- Epidermal growth factor receptor
- Protein son of sevenless
- Tyrosine-protein phosphatase corkscrew
- E3 ubiquitin-protein ligase CBL
- DShc protein
- Protein daughter of sevenless
- Ras-like protein 1
- Protein sevenless
- RH14395p
- Protein vav
Sequence:
MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVTPYHS
Protein: FLVCR heme transporter 1 (Feline leukemia virus subgroup C receptor-related protein 1) (Q5RGT2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Proton-coupled folate transporter
Sequence:
MVAGEFLQEQHVLPDSAPEGNTDEDSGYKELSNGSVHITLDPKVLEQELPPPDEKEAMLPAEQRSDALETRLYWRRFAVLAVFSLYSLVNAFQWIQYSIITNIFMDYYGVTSIAIDWLSVVYMVAYVPLIFPATWLLDKKGLRVTALLGAGLNALGAWVKCASVGPGLFWVTMTAQIICSVAQVFILGLPSRIASVWFGPREVSTACAFAVLGNQLGVAIGFLLPPVLVPNTADDKDLMGHNISIMFYGTAAVSTLLFLLTIFVIKDRPPLPPSKAQAVLSTGPAEDYSYKKSIINLFRNKPFILLLISYGIMTGSFYSVSTLLNQMIITHYKGEELNTGRIGLTLVVAGMFGSILCGIWLDRTKTYKLTTLIVYVLSFIGMVVFTFTLNVHLLVIFFTAGVLGFFMTGYLPIGFEFGVEITYPESEGTSSGLLNAFAQVFGIIFTLIQGKLTTDYNPLSGNIFLCAWILLGIVLTALIKSDLKRHDVNVGNINKAQAVSVPTELPSDKASSDVKMESSGLPHETTI
Protein: DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (ABC10-beta) (ABC8) (DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide) (P22139)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RBP10 is part of the core element with the central large cleft.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- DNA-directed RNA polymerase III subunit RPC9
- DNA-directed RNA polymerase I subunit RPA190
- DNA-directed RNA polymerase III subunit RPC1
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase III subunit RPC5
- DNA-directed RNA polymerase III subunit RPC10
- DNA-directed RNA polymerase III subunit RPC2
- DNA-directed RNA polymerase III subunit RPC4
- DNA-directed RNA polymerase III subunit RPC3
- DNA-directed RNA polymerase II subunit RPB11
Sequence:
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKFLRYNPLEKRD
Protein: Aspartate beta-hydroxylase domain-containing 1 (Aspartate beta-hydroxylase domain-containing protein 2) (E7F0P5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Seizure-related 6 homolog
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
- Double C2-like domain-containing protein alpha isoform X2
- BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1
- Protein yippee-like 3
- Proline-rich transmembrane protein 2
- Kinesin-like protein KIF22
- PAXIP1-associated glutamate-rich protein 1
- HIRA-interacting protein 3.
- TLC domain-containing 3Ba.
Sequence:
MSWSLDLVPLPPCSVLGGPPFSGLLWTVLLLFLWYCYRVGSDPPSHSGMLKSSSGRSSFSRSSSRSPVDPGLSSPKSSAAISLEAVEEEEGTESYLTPVLSHSPFPTDAAAGSRKLYRALQEYAKRYSWAGMGRIHKGLRNQARINDRLSIQKPHLFYLPDVPSIPFFPRDAHRHDIEVLEASYPIILAEFQAVYQKGIDTKLGWSYQGPKGQTVFPLYNAGVCVASNCRACPCSYRTLLSLRTFISSNSLGSAGFWLLGPGATLAGTYGPTNTRLRCHLGLQTPAQCELVVGGEPQCWSEGHCLLVDDSFLHTISHNGAAEDGPRVIFSVDLWHPNVAAAERQALDYIFAPEQ
Protein: Homeobox protein HMX1 (Homeobox transcription factor SOHo) (A9Y2A9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MHEKSQQQHTSTTSRGSSFFIENLLGSCRTEKPVCPIKDNDGTERANALKRYPNAYRKEMCVQASSAGFKTEISPLEWKGRETSRSPREESRNSSEYSRSDRDTPLASEPLDGVVDRKMSGCAVDEGDDARQLFDERSGPDTSEPGSARKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAADLEAVNFNHNSQRIVRVPILYHDKATPMSTLSFNVSQVSPPLMGFSNSVNYPLSSFAHSVNLMTSQMTGLV
Protein: Signal-transducing adaptor protein 2 (STAP-2) (Q8R0L1)
Organism: Mus musculus (Mouse)
Function: Substrate of protein kinase PTK6 (By similarity). May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12540842}. Membrane {ECO:0000269|PubMed:12540842}; Peripheral membrane protein {ECO:0000269|PubMed:12540842}. Note=The translocation to the membranes occurs in response to EGF when the protein is overexpressed in fibroblastic cells.
Interaction partners:
- Protein-tyrosine kinase 6
- Signal transducer and activator of transcription 3
Sequence:
MATALSPPRGPKLKGAPPSHYYESFLEKKGPCDQDYRKFWAGLQGLAICFYNSNRDLQPLEKLDLRLFSKLRDEALLGSSRDTAYHFSLVLRDQEVKFKVESLESCEMWKGFILTVVELRVPSNLTLLPGHLYMMAEVLTKEEVRRAAEVPWCFLQVSRLEAQLLLERYPECGNLLLRPGGDGKDSVSVTTRQILNGSPVVKHYKVKRAGSKYVIDVEDPFSCPSLEAVVNYFVTHTKRALVPFLLDEDYEKVLGFVDSDRENGESAWAVPSFRASGPALPANVLKPLPPVPVSVSSQEDKLPQLPPLPQLPDTDENYVTPIEDSPAAEYMNQDVSLSSQAVPLKPKKPARLPAKPPKPSVVPKPDLKAITSVWTRKLGGSSSQASSLVTRLGDITAELEEKLQKRRALEH
Protein: ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT) (Q09188)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:8675018}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Spindle pole body-associated protein sad1
- Karyogamy meiotic segregation protein 1
- Probable mitochondrial-processing peptidase subunit beta
- Uncharacterized mitochondrial carrier C1682.09c
- ATP synthase subunit beta, mitochondrial
- Cytochrome c
- Karyogamy meiotic segregation protein 2
- Uncharacterized protein C2G2.14
- Integral inner nuclear membrane protein ima1
- Lap-Emerin-Man domain protein 2
Sequence:
MATSSAAAAASTPVNANTITETKNSTFFFDFMMGGVSAAVSKTAAAPIERVKLLIQNQDEMIRAGRLSHRYKGIGECFKRTAAEEGVISLWRGNTANVLRYFPTQALNFAFKDKFKKMFGYKKERDGYAKWFAGNLASGGAAGAASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYRSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLVGPLEGNFLASFLLGWAVTTGSGVASYPLDTIRRRMMMTSGEAVKYSSSFECGRQILAKEGARSFFKGAGANILRGVAGAGVLSIYDQVQLLMFGKKF
Protein: Large ribosomal subunit protein uL14 (60S ribosomal protein L23) (P62830)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:36517592}.
Interaction partners:
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL30
- Large ribosomal subunit protein eL37
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein eL28
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS9
Sequence:
MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA
Protein: Probable 3',5'-cyclic phosphodiesterase pde-1 (EC 3.1.4.17) (O18696)
Organism: Caenorhabditis elegans
Function: Redundantly with pde-5, plays a role in the AFD thermosensory neurons to regulate microvilli receptive ending morphology, possibly by regulating cGMP levels.
Interaction partners:
- Calmodulin
- EF-hand domain-containing protein
- Calmodulin-like protein
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- Calmodulin-like protein
- EF-hand domain-containing protein
- Uncharacterized calcium-binding protein B0563.7
- AMP deaminase
- Adenylate kinase
Sequence:
MNRARKTSSCGCFRSAFCLLKPSTSSASEEHGDSDKKLLSVQLITPRDEEEQTSSRSIKIPPLDLNGLDCKKNAVAARRAGRRRTSEGGGVRGKGHFAEVVLDGLQRPVSLLRNQKEKSNSDDNCQEKEPTSPSSSRKKSYDNAPALESLEKLRYILHQLNSGQLPLEDLKRNIEYAALVLETAYMDETRRICDEDDDLAEVTPETVPDEVREWLAATFTRQNAGKKRDKPKFKSVANAIRTGIFFEKLFRKQQVVQCPIPPEIAELMKEVCTWSFSPFQLNEVSEGHALKYVGFELFNRYGFMDRFKVPLTALENYLSALEVGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKEDDKNILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPEGIDKNKALCLIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASMGLPYSPLCDRHTVHVADSQIGFIDFIVEPTMVVCGELLVKMVEPLVSLPPTDSLFPPSVDGGDDKSPSNALSPLPDLRNSSTSPSSIRRIPLNYAGKLDIPTPWMKFLHENKAHWKERAAKEEEERKIKEAAEAEAAAKQVEENKENGVTTN
Protein: Possible transferase (Possibly glycosyltransferase) (O06376)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible conserved membrane protein
- Uncharacterized protein Rv3630
- Probable conserved integral membrane protein
- Uncharacterized protein Rv3633
- UDP-glucose 4-epimerase
- Uncharacterized glycosyltransferase Rv0539
- Probable UDP-glucose 4-epimerase GalE3
- Glycosyltransferase involved in cell wall biogenesis
- S-methyl-5'-thioadenosine phosphorylase
- Probable conserved transmembrane protein alanine and leucine rich
Sequence:
MASKMDTETHYSDVWVVIPAFNEAAVIGKVVTDVRSVFDHVVCVDDGSTDGTGDIARRSGAHLVRHPINLGQGAAIQTGIEYARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGAGDVDVVIGTRFGRPVGKASASRPPLMKRIVLQTGARLSRRGRRLGLTDTNNGLRVFNKTVADGLNITMSGMSHATEFIMLIAENHWRVAEEPVEVLYTEYSKSKGQPLLNGVNIIFDGFLRGRMPR
Protein: SIN3 transcription regulator family member A (D3ZBP2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00810}.
Interaction partners:
Sequence:
MKRRLDDQESPVYAAQQRRIPGSTEAFSHQHRVLAPAPPVYEAVSETMQSATGIQYSVAPNYQVSAVPQSSGSHGPAIAAVHSSHHHPAAVQPHGGQVVQSHAHPAPSVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPTPAQPAPQPTPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRHSGTGATPPVKKKPKLISLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLESFPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLSSQTSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAEVWTRWSDYVERYMSSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTMENVESLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIKKYRVKYGTVFKAP