wanglab/gogpt-training-data huggingface dataset:
Protein: Nuclear distribution protein nudE (O74689)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Required for nuclear migration within hyphae during vegetative growth.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12631710, ECO:0000269|PubMed:16467375}. Note=Localizes to the plus ends of microtubules.
Interaction partners:
- Nuclear distribution protein nudF
- Nuclear movement protein nudC
- Kinesin-like protein
- Mitochondrial division protein 1
- Kinesin-like protein
Sequence:
MPSADEPSSTRTNGTSSRSDQLAYYKKQYEQLESELADFQASSRELEAELEKEIEASEKRERQLKEKVDNLRYEVEEWKSKYKQSKSEASTAQNALQKEITSLRDANLTLQLKLRDTEVANDDYERQARHTTSSLEDMESKYNQALEREVLLDMEYKQGEQERESLRIENQRLRDELNDLKIETEIVQERLRNNNRRRRPAPLGRSPSTPHTPEIFDRSPGESTVSSPLFSTPPTKLSLTLASATATPPSPPMSETSSSMRKSLTAASGFPLQKASASESFGTRSLYGNRPQRFQAHSRATSYAFSNGRSTPSATTTRPSLPKANNTTANRPSGIPKSGSLHQIRGLIGKMQKLEERVQSAKSKLPPPSETASRASSRAGSMLDASPGAATIAMRRDTRKRLSGSSFSSSVRDGDGAPSYVTSSRPSYGTRTQGDSRPSSRTSFSSSLSHSTHPSVTPSNRPESRQSRTKTPLGHYSTNPTTESRRPRSSLSNPAGQSTPINGMTYIDEDEDLAEQFNMRATISSTRPTRLPSFSNPAFSTPTGLKKRSTSGMSGIPAPRTLRRGNTMGPPKTKPKPVAGDLGETF
Protein: Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) (Q9QXK3)
Organism: Mus musculus (Mouse)
Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:17360540}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi. {ECO:0000250}.
Interaction partners:
- Coatomer subunit beta'
- Coatomer subunit beta
- Coatomer subunit delta
- Coatomer subunit alpha
- Coatomer subunit zeta-1
- Coatomer subunit epsilon
- Coatomer subunit zeta-2
- Transmembrane emp24 domain-containing protein 10
- N-terminal kinase-like protein
- Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
Sequence:
MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAVERYMKQAIVDKVSSVASSALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKESEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCHKYPRKHSVMMTFLSNMLRDDGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMALNATYIFNGLTVSIPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKSEITLVTPKPEKLAPSRQDIFQEQLAAIPEFMNLGPLFKSSEPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSDSYEVLCCIPAPSLPYNQPGICYTLVRLPDEDPTAVAGTFSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKILKPNFAAAWEEVGDAFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGVYRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG
Protein: Endothelial cell-specific chemotaxis regulator (Apoptosis regulator through modulating IAP expression) (ARIA) (Endothelial cell-specific molecule 2) (Q3TZW0)
Organism: Mus musculus (Mouse)
Function: Regulates endothelial chemotaxis and tube formation (By similarity). Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MRLGSAILGLLLLQGYSSQPTTTQTSQEILQKSSQVSLVSNQPVTPRSSTMDKQSLSLPDLMSFQPQKHTLGPGTGTPERSSSSSSSSSSRRGEASLDATPSPETTSLQTKKMTILLTILPTPTSESVLTVAAFGVISFIVILVVVVIILVSVVSLRFKCRKNKESEDPQKPGSSGLSESCSTANGEKDSITLISMRNINVNNSKGSMSAEKIL
Protein: Propionyl-CoA carboxylase, beta subunit (EC 6.4.1.3) (O06165)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MTTPSIAIAPSFADEHRRLVAELNNKLAAAALGGNERARKRHVSRGKLLPRERVDRLLDPGSPFLELAPLAAGGMYGDESPGAGIITGIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCIYLVDSGGAFLPRQDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSDEAVIVREQGTIFLGGPPLVKAATGEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVRAIADTFGPCEPAQWDVRRSVEPKYPQAELYDVVPPDPRVPYDVHEVVVRIVDGSEFSEFKAKYGKTLVTAFARVHGHPVGIVANNGVLFSESALKGAHFIELCDKRKIPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYEDQGNPYYSTARLWDDGIIDPADTRTVVGLALSLCAHAPLDQVGYGVFRM
Protein: Protein phosphatase 1 regulatory subunit (Q6NX94)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSCANVMSRFGPPVSVRSVDMAVGFRCRGSPHINHHLLMSSPKPLRPCISHQPVFEYRHSPSTGLLTKNGRREKRVAFADAKGLALITVRLFTEKEDNIPREPLKIPRLKKLGCAKEPAKATSRLKLGFEQPCCDYQAFRNRLQEHAVLLESCNVTKRSVLGTVRVKNVCFEKAVHVRITFDSWKTHLDVPCTYLDRCYGEPGTDVFEFNISVPEEIDPRERVEFCVSYLPATFAAAEWDNNNGKNYCIQVCD
Protein: Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.8) (Sulfide dehydrogenase-like) (Sulfide quinone oxidoreductase) (Q9Y6N5)
Organism: Homo sapiens (Human)
Function: Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro). It is believed the in vivo electron acceptor is glutathione.
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Persulfide dioxygenase ETHE1, mitochondrial
- Thiosulfate sulfurtransferase
- Methanethiol oxidase
- Sulfite oxidase, mitochondrial
- 3-mercaptopyruvate sulfurtransferase
- D-amino-acid oxidase
- Cystathionine gamma-lyase
Sequence:
MVPLVAVVSGPRAQLFACLLRLGTQQVGPLQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLETFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS
Protein: Quinoprotein ethanol dehydrogenase (QEDH) (EC 1.1.2.8) (Quinoprotein alcohol dehydrogenase (cytochrome c)) (Quinoprotein alcohol dehydrogenase (cytochrome c550)) (Q9Z4J7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Catalyzes the oxidation of ethanol and other primary alcohols to the corresponding aldehydes, except methanol, which is a very poor substrate. Uses a specific inducible cytochrome c550, encoded by the adjacent gene in the locus, as electron acceptor. Is a key enzyme of the carbon and energy metabolism during growth of P.aeruginosa on ethanol as the sole carbon and energy source. Is also able to use secondary alcohols as well as aminoalcohols like ethanolamine and 1-amino-2-propanol, and aldehydes as substrates.
Subcellular location: Periplasm {ECO:0000305|PubMed:9826187}.
Interaction partners:
- Cytochrome c550
- NAD+ dependent aldehyde dehydrogenase ExaC
- Coenzyme PQQ synthesis protein B
- Pyrroloquinoline-quinone synthase
- Glycerol metabolism activator
- Pentapeptide repeat-containing protein
- PqqA peptide cyclase
- alcohol dehydrogenase
- PqqA binding protein
- GfdT protein
Sequence:
MTTRTSPAPAGLLRPSLHCLAFAVALGSAGAALAKDVTWEDIANDDKTTGDVLQYGMGTHAQRWSPLKQVNADNVFKLTPAWSYSFGDEKQRGQESQAIVSDGVIYVTASYSRLFALDAKTGKRLWTYNHRLPDDIRPCCDVVNRGAAIYGDKVFFGTLDASVVALNKNTGKVVWKKKFADHGAGYTMTGAPTIVKDGKTGKVLLIHGSSGDEFGVVGRLFARDPDTGEEIWMRPFVEGHMGRLNGKDSTVTGDVKAPSWPDDRNSPTGKVESWSHGGGAPWQSASFDAETNTIIVGAGNPGPWNTWARTAKGGNPHDYDSLYTSGQVGVDPSSGEVKWFYQHTPNDAWDFSGNNELVLFDYKAKDGKIVKATAHADRNGFFYVVDRSNGKLQNAFPFVDNITWASHIDLKTGRPVEREGQRPPLPEPGQKHGKAVEVSPPFLGGKNWNPMAYSQDTGLFYVPANHWKEDYWTEEVSYTKGSAYLGMGFRIKRMYDDHVGSLRAMDPVSGKVVWEHKEHLPLWAGVLATAGNLVFTGTGDGYFKAFDAKSGKELWKFQTGSGIVSPPITWEQDGEQYLGVTVGYGGAVPLWGGDMADLTRPVAQGGSFWVFKLPSWDNRTASR
Protein: Pup deamidase/depupylase (EC 3.4.-.-) (EC 3.5.1.119) (Deamidase of protein Pup) (A0QZ49)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: Specifically catalyzes the deamidation of the C-terminal glutamine of the prokaryotic ubiquitin-like protein Pup to glutamate, thereby rendering Pup competent for conjugation. Probably also displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; thus may be involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins.
Interaction partners:
- Prokaryotic ubiquitin-like protein Pup
- Proteasome subunit alpha
- Proteasome subunit beta
- Proteasome-associated ATPase
- Ectoine hydroxylase
- Helicase XPB/Ssl2 N-terminal domain-containing protein
- DUF3052 domain-containing protein
- Bacterial proteasome activator
- L-ectoine synthase
Sequence:
MQRIIGTEVEYGISSPSDPTANPILTSTQAVLAYAAAAGIQRAKRTRWDYEVESPLRDARGFDLSRSSGPPPIVDADEVGAANMILTNGARLYVDHAHPEYSAPECTDPMDAVIWDKAGERVMEAAARHVASVPGAAKLQLYKNNVDGKGASYGSHENYLMSRQTPFSAVIAGLTPFMVSRQVVTGSGRVGIGPSGDEPGFQLSQRADYIEVEVGLETTLKRGIINTRDEPHADADKYRRLHVIIGDANLAETSTYLKLGTTSLVLDLIEEGVDLSDLALARPVHAVHVISRDPSLRATVALADGRELTALALQRIYLDRVAKLVDSRDPDPRASHVIETWANVLDLLERDPMECAEILDWPAKLRLLEGFRQRENLTWQAPRLHLVDLQYSDVRLDKGLYNRLVARGSMKRLVTEQQVLDAVENPPTDTRAYFRGECLRRFGADIAAASWDSVIFDLGGDSLVRIPTLEPLRGSKAHVGALLDSVDSAVELVEQLTN
Protein: DENN domain-containing protein C297.05 (Q9Y7Q7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Serine/threonine-protein kinase atg1
Sequence:
MESIADHFFLAGLSNGFVSVSNSQFRADRLDEDAISVSSSIIQNNTRKSPLKRVSITSESSFYKENTFAHHNTTGSNSVGPKKPFLDYHHSTSNTPTKKKKDSFDHASVTSLHRRSLSSNTSTPRKYHSRKPYSEPSVIDKEHLQNRVSIGTTHTQNDLYQSYVAYPDALPLFAATHPFERRYPPSLLHQFPSSKDIKNETPTIDRCDFPNYVPMFAFPNDITIKESDVRPVSTYHSFALTSDNNSHLYGICVVVWVAMPQSMQNDLEKECEVWRANNTTVEDREVAEKLLSSLETERSKLSSLLLKMQEKELEGSDSIDPILLEKIDVCEENIILYTELLRPMRYKLPRFVHGLTNNRTLWIPNAYGLLSKHSHLQSFCRDWLRIVCSSIQAEDLDFIPSSDLNSLKSLNLQSFVKNICCDVPLPPKGLLQLQVNVGPLNLYAFRSPVNEIPGWNDVDLYPLFRALSIPNILVLFEAALMEAKVIFLSENLGMLGYASQALLHLLYPLTWQGLYIPVLPRRLISCFEAPCSYIIGTLSYFFHMDDVPLDNIPLVVCDLDKNSVSTFGKIVRLSRSLRSKLQAHLKLAAPLHDKFYVPHSPPKYTMETYPNNVLSLSTVTCFPLREKFSIPALLSFRSSNFSKRPYVLSPILNGFLKLQDNPSSIYFAKQTDSRQSSASKLLYARLQAPEHARNFSSPPFTRPASPSSSKFRFSSSSFQSTIRRNSLTSPYSVPELRSSESNQNKAGSINTGSAVNLVSSKPGEQKVHIMYKEGHKLRRIYKMFPADSAGSICAVSGYALGDVHVQCDNCGLRVNLDFIKHISMPCVPACFNSQQILVTFLKFFIKILGSYRNYLRKPHMSRENFGISKGSGGLIGSFDFNKFTRQASKVHGSWISSLCSSQAFAEFIGDRCELDLNDPRVALFDQLLLCERNHGKPRLFGKATPFLRDKSLEIQRIEVAPIPASLKNDNALH
Protein: LRR receptor-like serine/threonine-protein kinase RGI2 (EC 2.7.11.1) (Protein RECEPTOR OF RGF1 3) (Protein RGF1 INSENSITIVE 2) (Protein ROOT CLAVATA-HOMOLOG1 1) (C0LGV1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Together with RGI1, RGI3, RGI4 and RGI5, acts as receptor of RGF peptides (e.g. RGF1, GLV5/CLEL1/RGF2, GLV7/CLEL3/RGF3, GLV3/RGF4, GLV10/CLEL7/RGF5 and RGF10/CLELN), peptide hormones which maintain the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT, e.g. PLT1 and PLT2). Links RGF peptides signal with their downstream components.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Calcium-binding EF-hand family protein
- Major facilitator superfamily protein
- Pathogenesis-related thaumatin superfamily protein
- Metallo-beta-lactamase family protein
- Protein GOLVEN 11
- Phototropic-responsive NPH3 family protein NPY4
Sequence:
MSLQMPIPRKKALTVSHFSITLSLFLAFFISSTSASTNEVSALISWLHSSNSPPPSVFSGWNPSDSDPCQWPYITCSSSDNKLVTEINVVSVQLALPFPPNISSFTSLQKLVISNTNLTGAISSEIGDCSELIVIDLSSNSLVGEIPSSLGKLKNLQELCLNSNGLTGKIPPELGDCVSLKNLEIFDNYLSENLPLELGKISTLESIRAGGNSELSGKIPEEIGNCRNLKVLGLAATKISGSLPVSLGQLSKLQSLSVYSTMLSGEIPKELGNCSELINLFLYDNDLSGTLPKELGKLQNLEKMLLWQNNLHGPIPEEIGFMKSLNAIDLSMNYFSGTIPKSFGNLSNLQELMLSSNNITGSIPSILSNCTKLVQFQIDANQISGLIPPEIGLLKELNIFLGWQNKLEGNIPDELAGCQNLQALDLSQNYLTGSLPAGLFQLRNLTKLLLISNAISGVIPLEIGNCTSLVRLRLVNNRITGEIPKGIGFLQNLSFLDLSENNLSGPVPLEISNCRQLQMLNLSNNTLQGYLPLSLSSLTKLQVLDVSSNDLTGKIPDSLGHLISLNRLILSKNSFNGEIPSSLGHCTNLQLLDLSSNNISGTIPEELFDIQDLDIALNLSWNSLDGFIPERISALNRLSVLDISHNMLSGDLSALSGLENLVSLNISHNRFSGYLPDSKVFRQLIGAEMEGNNGLCSKGFRSCFVSNSSQLTTQRGVHSHRLRIAIGLLISVTAVLAVLGVLAVIRAKQMIRDDNDSETGENLWTWQFTPFQKLNFTVEHVLKCLVEGNVIGKGCSGIVYKAEMPNREVIAVKKLWPVTVPNLNEKTKSSGVRDSFSAEVKTLGSIRHKNIVRFLGCCWNKNTRLLMYDYMSNGSLGSLLHERSGVCSLGWEVRYKIILGAAQGLAYLHHDCVPPIVHRDIKANNILIGPDFEPYIGDFGLAKLVDDGDFARSSNTIAGSYGYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPIDPTIPDGLHIVDWVKKIRDIQVIDQGLQARPESEVEEMMQTLGVALLCINPIPEDRPTMKDVAAMLSEICQEREESMKVDGCSGSCNNGRERGKDDSTSSVMQQTAKYLRSSSTSFSASSLLYSSSSSATSNVRPNLK
Protein: Reticulon-4 receptor-like 1 (Nogo receptor-like 2) (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Q86UN2)
Organism: Homo sapiens (Human)
Function: Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12694398}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:12694398}. Membrane raft {ECO:0000269|PubMed:12694398}. Perikaryon {ECO:0000250|UniProtKB:Q80WD0}. Cell projection {ECO:0000250|UniProtKB:Q80WD0}. Note=Localized to the surface of neurons, including axons. {ECO:0000250|UniProtKB:Q80WD0}.
Interaction partners:
- Reticulon-4
- Receptor-type tyrosine-protein phosphatase S
- Myelin-associated glycoprotein
- Oligodendrocyte-myelin glycoprotein
Sequence:
MLRKGCCVELLLLLVAAELPLGGGCPRDCVCYPAPMTVSCQAHNFAAIPEGIPVDSERVFLQNNRIGLLQPGHFSPAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGNPWDCGCRARSLWEWLQRFRGSSSAVPCVSPGLRHGQDLKLLRAEDFRNCTGPASPHQIKSHTLTTTDRAARKEHHSPHGPTRSKGHPHGPRPGHRKPGKNCTNPRNRNQISKAGAGKQAPELPDYAPDYQHKFSFDIMPTARPKRKGKCARRTPIRAPSGVQQASSASSLGASLLAWTLGLAVTLR
Protein: Glycogenin-1 (EC 2.4.1.186) (Glycogen synthesis initiator protein 1) (Glycogenin glucosyltransferase 1) (P36143)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Self-glucosylating initiator of glycogen synthesis. Catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues. These chains act as primers for the elongation reaction catalyzed by glycogen synthase. Capable of transferring glucosyl residues to unbound acceptors such as free oligoglucans or oligoglucan derivatives.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:C4R941}. Vacuole {ECO:0000250|UniProtKB:C4R941}. Note=Localizes to glycogen granules (glycosomes) in the cytoplasm. Localizes to the vacuole during nitrogen starvation-induced glycophagy (autophagy of glycosomes). {ECO:0000250|UniProtKB:C4R941}.
Interaction partners:
- Glycogen [starch] synthase isoform 2
- Glycogen [starch] synthase isoform 1
- 1,4-alpha-glucan-branching enzyme
- UTP--glucose-1-phosphate uridylyltransferase
- Probable UTP--glucose-1-phosphate uridylyltransferase
- Glycogenin-2
- Alpha,alpha-trehalose-phosphate synthase 56 kDa subunit
- Trehalose-phosphatase
- Trehalose synthase complex regulatory subunit TSL1
- Trehalose synthase complex regulatory subunit TPS3
Sequence:
MYKKLAIATLLYSADYLPGVFALGHQVNKLLEEAGKKGDIETCLIVTTSLFNGTLSELAKNILQSIYTKIVLVEPLNCQEESIQKNSENLALLERPELSFALIKARLWELTQFEQVLYLDSDTLPLNKEFLKLFDIMSKQTTSQVGAIADIGWPDMFNSGVMMLIPDADTASVLQNYIFENTSIDGSDQGILNQFFNQNCCTDELVKDSFSREWVQLSFTYNVTIPNLGYQSSPAMNYFKPSIKLIHFIGKHKPWSLWSQKNFIKNEYHDQWNEVYEEFKEEHQLNNEVSKPKISDSDKTETPETITPVDAPPSNEPTTNQEIDTISTVEENVDNQNAEPVPNSDHSPAPNPVPLDFTKWLTTFINKDHLTNQPVNESREYSKENDNNIINSSSNRDQESPPNSTQELNSSYSVVSTQADSDEHQNAEEEDSTTDNASNSGEESHLDDISTAASSNNNVSNQPDGKNFSNSKENNISVESSPSNPEQKRSTDNIQKPSVSTNDLPDDVEPHTSVDDNIQYLEKDKEGYEEFLPDVYESNAIDNEEEFFDDDARDATEGETKTSAVADKQEDMKLTAEETNQPQQEMPNFKFDWEDSDYLSKVERCFPDDIFEYAVE
Protein: Uncharacterized protein YmgD (P0AB46)
Organism: Escherichia coli (strain K12)
Interaction partners:
- UPF0757 protein YmgG
- Uncharacterized protein YjbG
- Uncharacterized protein YmgI
Sequence:
MKKFALLAGLFVFAPMTWAQDYNIKNGLPSETYITCAEANEMAKTDSAQVAEIVAVMGNASVASRDLKIEQSPELSAKVVEKLNQVCAKDPQMLLITAIDDTMRAIGKK
Protein: Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) (60S ribosomal protein L10E) (Q9PV90)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P05388}. Cytoplasm {ECO:0000250|UniProtKB:P05388}.
Interaction partners:
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein eS21
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein eS25
- Ribosomal protein L26
- Large ribosomal subunit protein eL28
- Large ribosomal subunit protein eL42
- Small ribosomal subunit protein uS11
- 60S ribosomal protein L7a
Sequence:
MPREDRATWKSNYFLKIIQLLDDFPKCFIVGADNVGSKQMQTIRLSLRGKAVVLMGKNTMMRKAIRGHLENNPALERLLPHIRGNVGFVFTKEDLTEVRDLLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKPGDKVGASEATLLNMLNMLNISPFSYGLIIQQVYDNGSVYSPEVLDITEDALHKRFLKGVRNIASVCLQIGYPTLASIPHTIINGYKRVLAVTVETDYTFPLAEKVKAYLADPTAFAVAAPVAAATEQKSAAPAAKEEAPKEDSEESDEDMGFGLFD
Protein: Transthyretin (crocTTR) (Prealbumin) (O55245)
Organism: Crocodylus porosus (Saltwater crocodile) (Estuarine crocodile)
Function: Thyroid hormone-binding protein, with a much higher binding affinity for triiodothyronine (T3) than for thyroxine (T4). Probably transports triiodothyronine from the bloodstream to the brain.
Subcellular location: Secreted {ECO:0000269|PubMed:12228058}.
Interaction partners:
Sequence:
MAFHSMLLVFLAGLVFLTEAAPLVSHGSIDSKCPLMVKVLDAVRGSPAANVAIKVFKKTSDGDWQEFAAGKTTEFGEVHELTSDEKFVEGIYRVEFDTSSYWKALGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE
Protein: Lysine-specific permease (P32487)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High-affinity permease for lysine.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- High-affinity methionine permease
- L-2-aminoadipate reductase
- Uracil permease
- Protein LDB19
Sequence:
MGRFSNIITSNKWDEKQNNIGEQSMQELPEDQIEHEMEAIDPSNKTTPYSIDEKQYNTKKKHGSLQGGAIADVNSITNSLTRLQVVSHETDINEDEEEAHYEDKHVKRALKQRHIGMIALGGTIGTGLFVGISTPLSNAGPVGSLIAYIFMGTIVYFVTQSLGEMATFIPVTSSITVFSKRFLSPAFGVSNGYMYWFNWAITYAVEVSVIGQVIEYWTDKVPLAAWIAIFWVIITLMNFFPVKVYGEFEFWVASVKVLAIMGYLIYALIIVCGGSHQGPIGFRYWRNPGAWGPGIISSDKSEGRFLGWVSSLINAAFTYQGTELVGITAGEAANPRKTVPRAINKVVFRIVLFYIMSLFFIGLLVPYNDSRLSASSAVIASSPFVISIQNAGTYALPDIFNAVVLITVVSAANSNVYVGSRVLYSLARTGNAPKQFGYVTRQGVPYLGVVCTAALGLLAFLVVNNNANTAFNWLINISTLAGLCAWLFISLAHIRFMQALKHRGISRDDLPFKAKLMPYGAYYAAFFVTVIIFIQGFQAFCPFKVSEFFTSYISLILLAVVFIGCQIYYKCRFIWKLEDIDIDSDRREIEAIIWEDDEPKNLWEKFWAAVA
Protein: Thioredoxin (Q9NG23)
Organism: Trypanosoma brucei brucei
Interaction partners:
Sequence:
MSVVDVYSVEQFRNIMSEDILTVAWFTAVWCGPCKTIERPMEKIAYEFPTVKFAKVDADNNSEIVSKCRVLQLPTFIIARSGKMLGHVIGANPGMLRQKLRDIIKDN
Protein: BcDNA.GH02678 (Vacuolar protein sorting 4, isoform A) (Vacuolar protein sorting 4, isoform B) (Q9Y162)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endosome membrane {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004481}.
Interaction partners:
- Vacuolar protein sorting-associated protein VTA1 homolog
- RH72336p
- Charged multivesicular body protein 1, isoform A
- Charged multivesicular body protein 4
- Vacuolar protein sorting 20, isoform A
- IST1 homolog
- Tumor suppressor protein 101
- GH14561p
- Charged multivesicular body protein 5
- Charged multivesicular body protein 2b
Sequence:
MAAGTTLQKAIDLVTKATEEDRNKNYAEALRLYEHGVEYFLHTIKYEAQGEKAKDSIRAKCLQYLDRAEKLKEYLKKGKKKPIKEGGESSAKDDKDKKSDSDDEDGDDPEKKKLQSKLEDAIVIEKPKVQWSDVAGLDAAKEALKEAVILPIKFPQLFTGKRIPWKGILLFGPPGTGKSYLAKAVATEANRSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEIDSMCSARSDNENDSVRRIKTEFLVQMQGVGNDTDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARLVMFKIHLGNTTHVLTEQDLKELAGKTEGYSGADISIVVRDALMEPVRKVQTATHFKRVSGPSPTNHEEIVNDLLVPCSPGDQGAVEMNWMDVPSDKLFEPPVTMRDMLKSLSRTKPTVNEDDLKKLRKFTEDFGQEG
Protein: Max-interacting protein 1 (Max interactor 1) (O09015)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.
Subcellular location: Nucleus.
Interaction partners:
- Protein max
- Cell division cycle protein 27 homolog
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Cell division cycle protein 20 homolog
- Anaphase-promoting complex subunit 4
- Paired amphipathic helix protein Sin3a
- Mitotic checkpoint serine/threonine-protein kinase BUB1
Sequence:
MERVKMINVQPMLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFTS