wanglab/gogpt-training-data huggingface dataset:
Protein: Butyrophilin subfamily 2 member A2 (Q8WVV5)
Organism: Homo sapiens (Human)
Function: Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Xanthine dehydrogenase/oxidase
- Perilipin-2
- Lactadherin
Sequence:
MEPAAALHFSLPASLLLLLLLLLLSLCALVSAQFTVVGPANPILAMVGENTTLRCHLSPEKNAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEYRGRITFVSKDINRGSVALVIHNVTAQENGIYRCYFQEGRSYDEAILRLVVAGLGSKPLIEIKAQEDGSIWLECISGGWYPEPLTVWRDPYGEVVPALKEVSIADADGLFMVTTAVIIRDKYVRNVSCSVNNTLLGQEKETVIFIPESFMPSASPWMVALAVILTASPWMVSMTVILAVFIIFMAVSICCIKKLQREKKILSGEKKVEQEEKEIAQQLQEELRWRRTFLHAADVVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVMVWTVGVCRHSVERKGEVLLIPQNGFWTLEMFGNQYRALSSPERILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRSAFTVPVRPFFRLGSDDSPIFICPALTGASGVMVPEEGLKLHRVGTHQSL
Protein: All-trans retinoic acid-induced differentiation factor (Apoptosis-related protein 3) (APR-3) (p18) (Q6UW56)
Organism: Homo sapiens (Human)
Function: Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway.
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:21723284}. Cell membrane {ECO:0000269|PubMed:17524364}; Single-pass membrane protein {ECO:0000269|PubMed:17524364}. Lysosome membrane {ECO:0000269|PubMed:29745899}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with NELL1 on the nuclear envelope and the perinuclear region (PubMed:21723284).
Interaction partners:
- Melanoma-associated antigen H1
- Sugar phosphate exchanger 3
Sequence:
MAPHDPGSLTTLVPWAAALLLALGVERALALPEICTQCPGSVQNLSKVAFYCKTTRELMLHARCCLNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIIDLQANPLKGDLANTFRGFTQLQTLILPQHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQGSFSLLMFFGILGATTLSVSILLWATQRRKAKTS
Protein: Nebulin (A0A1B0GSI0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MADEEEYEEVIEYYTEETVYEEVPGETITEVYETTTTRTSDYGQSETATPALAQPQPAKPVERKKVIRKKVDSSKFMTPYIQHSQKMQDLFSSNKYKENYEKAKGQPYAITSDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKALFYPYNDSPELRRVAQAQKALSDIAYKKGLTEQQTQFTSLPDPPEVEFAKKVTNQVSK
Protein: Exosome complex component RRP45A (Protein ECERIFERUM 7) (RRP45 homolog A) (Ribosomal RNA-processing protein 45A) (AtRRPA5a) (Q9LDM2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable 3'->5' exoribonuclease involved in the regulation of cuticular wax biosynthesis. Can perform exosomal functions and partially complement the yeast rrp45 null mutant.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17351114}. Nucleus {ECO:0000269|PubMed:17351114}. Note=Excluded from the nucleolus.
Interaction partners:
- Exosome complex component RRP41 homolog
- Exosome complex component RRP4 homolog
- Exosome complex exonuclease RRP46 homolog
- Ribosomal RNA-processing protein 43
- Ribosomal RNA-processing protein 42
- Exosome complex component RRP41-like
- DExH-box ATP-dependent RNA helicase DExH10
- Nuclear nucleic acid-binding protein C1D
- Exosome complex exonuclease RRP44 homolog A
- Protein RRP6-like 2
Sequence:
MEGRLNNMWRLTVNESKFVESALQSELRVDGRGLYDYRKLTIKFGKEYGSSQVQLGQTHVMAFVTAQLVQPYKDRPSEGSFSIFTEFSPMADPSFEPGHPGESAVELGRIIDRALRESRAVDTESLCVLAGKLVWSVRIDLHILDNGGNLVDAANVAALAALMTFRRPDCTVGGDNSQDVIIHPPEEREPLPLIIHHLPIAFTFGFFNKGSILVMDPTYVEEAVMCGRMTVTVNANGDICAIQKPGEEGVNQSVILHCLRLASSRASATTKIIRDAVEAYNRERSSQKVKRHHTLAKSEVLGPIVVV
Protein: Adenine deaminase (Adenase) (Adenine aminase) (EC 3.5.4.2) (P31441)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Adenine phosphoribosyltransferase
- Putative xanthine dehydrogenase FAD-binding subunit XdhB
- Putative xanthine dehydrogenase molybdenum-binding subunit XdhA
- Purine nucleoside phosphorylase DeoD-type
- Putative xanthine dehydrogenase iron-sulfur-binding subunit XdhC
- Hypoxanthine phosphoribosyltransferase
- Aldehyde oxidoreductase iron-sulfur-binding subunit PaoA
- AMP nucleosidase
- Pyrimidine-specific ribonucleoside hydrolase RihB
- Aldehyde oxidoreductase FAD-binding subunit PaoB
Sequence:
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
Protein: Uncharacterized protein C736.07c (O74953)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MNDERLVAINFEQQIFSKISEISESVGRAIRYCKEDGKVEGCETASHVDFLNHIHLLLGNYNNDLASSIEKKKSELIVRNSEGLPVMDIHEEVDKDGNIISASVAPQRISSVIDYADVFRSLPGFKNIENGGNRDTSSRIEELSEEEINDSTKNINYKAPEMGSLPSNTEFTSTPTLGVSEFPSKHGDHSDSKTYESPISNSQAASLSDSDMVQQIKNGSKTSLFKKGFLFKKNNAMQNRTTSNIKSNASAIEKNKETILNALNNSTLNENGHQDTQNEVLRDIVLEHPTAKAQDTGESNKDNNTSTSKHKKRPKRLSKFKQAKLETKKSGNKDHATSSEKLSLGNESIHSINETRSSSIEEPDNADNKIVEEEPMLLPVPTTAQGQNVLEAVQYDGLDSLEDMEALIQEMEEEGELDDNSESEEDEHGMTIGFSKELKAPPDPQYFTEKTGATTYVNGNDESLNVSDFPQIVEQEELSSKNPRKVHFSDTLEIKHVSRSGKANIEVIPAPTEEYDNLFGPDDFQSRISAFRKARSKLRAKENEEGNHSNATCTIKNDDLSNTLNNRAANTKLNPKEEDKSTVESELKAPPKEKSSETSKEYLNEPSVVKDFVVERTPSDKISESKEAFDAKVEEISDQRAISQRYYELRKKMIDNTGEYIKDEEEQAVIPLDENGNEKPKMSRFMTARLRGRVPIYEH
Protein: SOSS complex subunit B2 (Nucleic acid-binding protein 1) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2A) (Sensor of single-strand DNA complex subunit B2) (Sensor of ssDNA subunit B2) (SOSS-B2) (Single-stranded DNA-binding protein 2) (Q8BGW5)
Organism: Mus musculus (Mouse)
Function: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:16533169}. Note=Localizes to nuclear foci following DNA damage. {ECO:0000250}.
Interaction partners:
- Integrator complex subunit 3
- Integrator complex subunit 5
- SOSS complex subunit C
- Integrator complex subunit 1
- SOSS complex subunit B1
Sequence:
MHGVNDPPLFIKDIKAGLKNLNVVFIVLEIGRVTKTKDGHEVRSCKVADRTGSITISVWDEIGGLIQTGDIIRLTRGYASMWKGCLTLYTGRGGELQKIGEFCMVYSEVPNFSEPNPDYRGQQNRGVQNEQKDKLSTNTFGPVGNGDQTGPESRGYHLPYGRSNGPGPISPQLPGTPSSQTVRTTISNARDPRRAFKR
Protein: Zinc finger SWIM domain-containing protein 1 (Q9CWV7)
Organism: Mus musculus (Mouse)
Interaction partners:
- Uncharacterized protein ZSWIM9
Sequence:
MALTMLNGLLIKDSSPPMLHQISKTPQLDAFNYQSCFMQDLFAHFPEVLFIHRTYNPRGKVLYTFLVDGPRVQVEGPLARAVYFAIPTNEDARGLAQMFQVFKKFNPAWERVNTILVDPHFLLLPTLTMEFPTAEVLLSAFHICKFLQGKFYQLPLEQPVQRLLLSSLQSTMCSATAGNLRKLYTLLNNCIPSSRLPELHSHWLLNDRIWLAHRWRSRAQSSRYFQSLEIMAHILSQFFGTTPFEKQGMASVFRYMQQNSSDKASLSLAETPQDSHTPSEASAENPNTEQLVEARIQHSLNAICTGPAAQLCLGELAVVQKSMHLIGSGSEKMSIQILEDTHTVQPQPPASCSCYFNQAFHLPCRHILAMLSARQQVLQPDMLPAQWTSGCASSLDSILGSKWSASLDKHLAVTLLTEEVGRLLQHCSEEEFERRYSTLRELADNWIGPYEQVQL
Protein: H0423H10.9 protein (Q9FSQ4)
Organism: Oryza sativa (Rice)
Interaction partners:
Sequence:
MAMTLRFPAGGATSVPAAMPHRVPMATAPSRLPATVAMALISTPSAAIRLTPINSATHFDVLRLRARRTDGEDDVSALPEIDGAASALPCTASTASPRSCVPGFPNTQSAFPNTRLSLLGWILKLVQERFSGDPSLLSSLLVLLIGGWQTAYFKEAVERRIKGSMRIPPCILTIFTFCAAVATLLYKAVKASEELDGIISHLIKKFEKLLESHDVKTQSEKLPEPREAEAKSQAKEVKTQDKS
Protein: TNF receptor associated factor 7 (F7FIY6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSSAKSARYNRFSGGPANLPASDSSGTRMETTFGPTFSTVTTITKADGTSTYKQHRRTPSSSSTLAYSPRDEEDGMPPINTPRRSDSAISVRSLHSESSMSLRSTFSLPEEEEEPEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKSEKCPVDNAKLTVVVNNIAVAEQIGELFIHCRHGCRAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRPVRCPNNPSCPPLLKMNLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLNDELSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLWAQGEGLGSCHPLQVWDIQNLQKVNTIRAHDNPVCTLVSSHNMLFSGSLKAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSGSYQTIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGAVDSTVKVWTC
Protein: Actin-related protein 3 (Actin-like protein 3) (Actin-related protein C) (P42528)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general role in the rapid activation and adaptation of the actin system to its multiple functions.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11807934}. Cytoplasm, cytosol {ECO:0000269|PubMed:11425877}. Cytoplasm, cell cortex {ECO:0000269|PubMed:11425877}. Cell projection, pseudopodium {ECO:0000269|PubMed:11425877}.
Interaction partners:
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2
- Actin-related protein 2/3 complex subunit 2
- Actin-related protein 2/3 complex subunit 1
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 5
- Wiscott-Aldrich syndrome protein
- WASP-related protein
- ADF-H domain-containing protein
- SPIN90/Ldb17 leucine-rich domain-containing protein
Sequence:
MNPASGLPAVVIDNGTGYTKMGYAGNNDPSFIIPTTIATQSSKGKQTAASQKKGVEDLDFFIGDEAIANSKTYDMTNPVKHGQIENWTHMEQYWEHCVFKYLRCEPEDHYFLLTEPPLNAPENREFTAEIMFETFNVPGLYIAVQAVLALAASWTSKNAEKTLTGTVIDSGDGVTHVIPISEGYVIGSSIKHIPIAGRDISSYVQQIMREREPNIPPAESLEIAKRVKEQYSYVCPDIVKEFGKYDSEPDKWIKTINAQDSVTKKPFSYDVGYERFLGPELFFNPEIASSDYLTPLPKVVDDTIQSCPIDCRRGLYKNIVLSGGSTMFKDFGKRLQRDVKRSVDYRIKRSEELSGGKIKAVPLAVNVISHNMQRYAVWFGGSMLASTPEFYNVCHTKAQYDEIGPSICRFNTVIGGIN
Protein: Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) (Non-classical export protein 103) (Q5AJ71)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Catalyzes the reversible hydration of CO(2) to H(2)CO(3). The main role may be to provide inorganic carbon for the bicarbonate-dependent carboxylation reactions catalyzed by pyruvate carboxylase, acetyl-CoA carboxylase and carbamoyl-phosphate synthetase. Involved in protection against oxidative damage. Acts as a CO(2) chemosensor and induces CO(2)-mediated filamentation. Essential for pathological growth in niches where sufficient CO(2) is not supplied by the host. Necessary for white-to-opaque switching at low CO(2) concentrations.
Subcellular location: Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Interaction partners:
- Carbonic anhydrase
- Uncharacterized protein
- Probable lysine/arginine permease CAN2
- Alpha-aminoadipate reductase
- Phosphatidyl synthase
Sequence:
MGRENILKYQLEHDHESDLVTEKDQSLLLDNNNNLNGMNNTIKTHPVRVSSGNHNNFPFTLSSESTLQDFLNNNKFFVDSIKHNHGNQIFDLNGQGQSPHTLWIGCSDSRAGDQCLATLPGEIFVHRNIANIVNANDISSQGVIQFAIDVLKVKKIIVCGHTDCGGIWASLSKKKIGGVLDLWLNPVRHIRAANLKLLEEYNQDPKLKAKKLAELNVISSVTALKRHPSASVALKKNEIEVWGMLYDVATGYLSQVEIPQDEFEDLFHVHDEHDEEEYNPH
Protein: Nuclear receptor-interacting protein 2 (Neuronal-interacting factor X 1) (Q9JHR9)
Organism: Mus musculus (Mouse)
Function: Down-regulates transcriptional activation by nuclear receptors, such as NR1F2.
Subcellular location: Nucleus {ECO:0000269|PubMed:10860982}.
Interaction partners:
Sequence:
MSTGQEARRDEGDSRKEQEASLRDRAHLSQQRQLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPHSVIQRRLVEGNQRRLQGESPLLQALIRGHDSSRTSATQVPALLVNCKCQDQMLRVAVDTGTQHNQISAGCLRRLGLGKRVPKAPGGDVAPEPPTQVEQLELELGQETVACSAQVVDVDSPEFCLGLQTLLSLKLATSLSASSLLPSALGIPTESICDSEALVPHSLLSLPKCTTKSLTEKDLQQMGSRLHPGCRGQSYLLPPLA
Protein: LD24793p (RNA and export factor binding protein 1) (Q9V3E7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- THO complex subunit 2
- ATP-dependent RNA helicase WM6
- Hpr1
- Nuclear RNA export factor 1
- THO complex subunit 5
- Eukaryotic initiation factor 4A-III
- FI07663p
- FI21285p1
- THO complex subunit 6
- LD14924p
Sequence:
MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTGGQQRFAGGARRGGANAGGSPRKPGSVLKGPRGGVAAGAVQKAKFPRGDVNSAWKHDMYDGPKRGAVGGGSGPTRLIVGNLDYGVSNTDIKELFNDFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQLAVSDVAVLTRPVAATDVKRRVGGTAPTSFKRGGGQAGGTARRGFKRPVGGKPAAGGQRRERKAPPTAEELDAELDSYINDMKI
Protein: EEA1 (FYVE-type domain-containing protein) (G5ED80)
Organism: Caenorhabditis elegans
Interaction partners:
- small monomeric GTPase
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Dynamin
- ADP-ribosylation factor 6
- Vacuolar protein sorting-associated protein 35
- Probable clathrin heavy chain 1
- PX domain-containing protein
- Sorting nexin-27
- Actin
- FYVE-type domain-containing protein
Sequence:
MLRRLKEQVSQVANDIDGRLNNSRPSISSQGSQSQSQKSENDQEIEGFLCPMCMVELGGPDELTVHFEKEHSDFQTSANRNHPDYTPPQQAPLAFATKDQEIEELRIRVNEEKRFAERIKEELDNIKSVMAIASEVTEDEIPYMAQQIQVLTADKGMVTRQFLELEKESGQQSRELQQVKQERGDLMAKLKQMSVTMREITDESESGKVEMEDLKRELKVVKSDVVRYEIEVSRLEKMLDQRPSEDDVNVLRTELVNAQKLMDAISQEKDIEIKEHLNSIRNLSMEREKQHIVNENLEKKIGEGEETVKQLQISYDAQSEELKQRNERVVQLEARIEENVFELSENKQNVKRLEDKVQESQDALQMLSNINGSNEEQMISLNSKFERNTAERKRIEAVFEEKVTVQGERLKTLEMANLDLTNELASMGSLLDKERSLLEEKNKEISERDSSINDLKEKLAESEKKATKYKNELKEHADLVENLTLQLNKLQENSKDLMEKISAGEGGAKMAIEQLEQEKVKLTNELQTSSEKTKKASGELEAKISELEKKLRDAEASRTDKEQKWKQEKESFERKLAEAEDEIKRKGERFVEMEKEMEEERQKATDRTLKLKDALVNSEKNLETIKKESEDREKIVREKDAHLEENKKRIEDAVQKLEEAEKRARELEASVSSRDTTVSTKESELSELKGKLTESNSFIEELKVQVEKVSNEISEKQQEVENLMAEMRDKEAHWKTKRDEFEAQMLRNQEDNEEASSTLKSVQEQLMKEKETSGEEKNQLISVKSQLEELKTEVERLIRSEEEKTQEIEKLKSAVTATTQERDELTATSESLRTECENLNSKIQSIEESRRHAEEKGSENLERMITEKSRLEKDIEERESTIQSIQEALETKDNEIESLKTTQRVVEDELVSKISHIESFNSRIEEFEKEMASGKRTIERLEAEKAEETEKLVVFTGTQSQKQEELEKLQKEIQEKETTIARMTSSKTQFEAMFADVQQTLSKEINDKTEEIERLMERIDSLEKVNHSRIEELESRLTQRERVVESLEADLAAVRNIEQEKLDELQKLKEEFDELKKAETMWQAEKDMLIERCLGSESDIEYEKERSQENKRRFDDALSAMHELGRANQSLQIDADRYSSRKWLDDAEAINCTECGKVFSLTVRKHHCRVCGKIYCNPCSSKSVRIASAKNPVRACNTCFTDSQK
Protein: Chromatin binding protein, putative (Q38AL3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAPYAVVGACSAATYGREETIEILGKRLEAGDTLLKVAYCAKHYGVALFRSGCLILLAPGSPEYHGSTVQNGEDNVKDVAAGDTHIVFCKEDGTVHSFGYSNIYGQLGDGSVWTSHKAEGGEDSDDRVPALSAPKMISGFGNGSYDVDGGDVIEGRRLCVPITAVSCGSHHTLLMTRKCNAVYGCGLGLSGQLGGKRKPPLQASFKSIRLLFGLPIRQIAAAGNHSFVLLQTGKLLAFGDNTSGQLGLGSTKAVGTPTPVTIRSVSPQPRGNENLDSYAIKTLRAAWGSAESMYFPLRVERISPELGPGEARIVSIWCSANRSVLLTSDMDWLSCGLPISRSRCIGDGQQQRMDRYGALGRWIKDKRESTWFGKMRWSERLGVAIKTTFPSLAGDALLEAARSEVRLVCFNHFVVLLIPGKDASNKSLLFLQGEGQSVEAVQGGERLSVAAVARADKLLQDREVDDDSCEYALSGGHAIVATDHFLAVI
Protein: Receptor-like protein kinase ANXUR2 (EC 2.7.11.1) (Q3E8W4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Receptor-like protein kinase that controls pollen tube behavior by directing rupture at proper timing to release the sperm cell.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19646876}; Single-pass type I membrane protein {ECO:0000269|PubMed:19646876}.
Interaction partners:
- Receptor-like protein 7
- Rapid alkalinization factor 23
- Protein RALF-like 1
- GPI-anchored protein LLG3
- GPI-anchored protein LORELEI
- GPI-anchored protein LLG1
- GPI-anchored protein LLG2
- Cyclase-associated protein 1
- Protein RALF-like 15
- Calcium-transporting ATPase 9, plasma membrane-type
Sequence:
MNEKLRILFSFLCFFYVLLVSPSQSNGQDISLSCGASEPAVDQDKKKWEPDTKFLKTPNTVHAPATYQDPSLLSTVPYMTSRIFTAPATYEIPVKGDKRHMLRLHFYPSTYTGLNILDSYFSVAANDLTLLSNFSAAITCQALTQAYLVREYSLAPSEKDVLSIIFTPSDKHPKAFAFINGIEVIPMPELFDTASLVGFSDQTSDTKTANLQTMFRLNVGGQDIPGSQDSGGLTRTWYNDAPYIFSAGLGVTLQASNNFRIDYQKMPVSTAPADVYKTARSQGPNGDINMKSNLTWMFQVDTNFTYIMRLHFCEFQLAKINQKVFNIFINNRTAQGDTNPADILGWTGGKGIPTYKDYAIYVDANTGGGGEEISLQMTPSTFGQPEYYDSQLNGLEIFKIDTMKNLAGPNPKPSPMQANEDVKKDFQGDKRITAFVIGSAGGVAAVLFCALCFTMYQRKRKFSGSDSHTSSWLPIYGNSHTSATKSTISGKSNNGSHLSNLAAGLCRRFSLSEIKHGTHNFDESNVIGVGGFGKVYKGVIDGGTKVAIKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLIYDYMSLGTLREHLYNTKRPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDENWVAKVSDFGLSKTGPNMNGGHVTTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEVLCARPALNPSLSKEQVSLGDWAMNCKRKGTLEDIIDPNLKGKINPECLKKFADTAEKCLSDSGLDRPTMGDVLWNLEFALQLQETADGSRHRTPSNGGGSVDLGGGGGGVTVNISAGESDLGDDLSSEENSGIFSQIVNPKGR
Protein: Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (Parafibromin isoform 1) (X1WHN7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RNA polymerase-associated protein LEO1
- RNA polymerase-associated protein CTR9 homolog
- RTF1 homolog, Paf1/RNA polymerase II complex component.
- RNA polymerase II-associated factor 1 homolog
- FACT complex subunit
- Superkiller complex protein 8
- Transcription elongation factor SPT5
- DNA-directed RNA polymerase subunit
- Transcription elongation factor SPT4
- Transcription elongation factor SPT6
Sequence:
MADVLSVLRQYNIQKKEIVAKGDEVIFGEFSWPKNVKTNYVIWGTGKEGQPKEYYTLDSILFLLNNVHLPHPSYVRRAATENIPVVRRPDRKDLLSYLNGESSSSTSIDRSAPIEIGLQRPTQVKRAADEVSSEAKKPRVEDEERVRLDKERLAARLEGHKESIVQTDQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITQKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSSGKNFSKNIFAILQSVKAREEGRAPEQRQTQNQTQVDPAIRNKQPVPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKAQTPAMQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTSLITMLNAKDLLQDLKFVTSEEKKKQGIQRDNEVLLQRRKDQVQPGGATLSVTVPYRVIDQPLKLAPQDWDRVVAVFVQGPAWQFKGWPWLLPDGSPVDIFAKIRAFHLKYDEARMDPNVQKWDVTVLELSHHKRHLDRPVFLRFWETLDRYMVKHKSHLRF
Protein: alanine transaminase (EC 2.6.1.2) (Q7TP13)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Aspartate aminotransferase, mitochondrial
- Aspartate aminotransferase, cytoplasmic
Sequence:
MTKATLIRTTFNWSRLTGSKRFSPLSTRREHGSIQAGLVQEELRVLHLHLKAASGRLTSRKLGDTQASFWTSCGIKKPFTEVIRANIGDAHAMGQQPITFLRQHSFLRGALGDGGFMVYVRISMAECCMDRQYWIGRQETGNEVMALCTYPNLLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFITRRDGVPADPDNIYLTTGASDGISVCAKTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEDNCWALNVDELRRALRQAKDHCDPKVLCIINPGNPTGVSHHTQLNFRTVTDYFKLGGGRSDGDGDDDGGGGGGGDDDDDDDDDVTGIYSGSLDSNCDFQVYQDNVYSPDCRFHSFKKVLYQMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVPGEESFEQFTRGHGKGTATTPCGQLPVVCLGVSIHGRLSRGTVNSKIQTTKLTLILPWEAEGGEPEKESVLGNLAKKAKLTEDLFNQVPGIQCNPLQGAMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRQEAERANSKGEESFERPPVIYFLHKATTPNLPQLTANLAAKQSNAQDLWEGMSMASEKIEEAQHWKRGATPGVVNNLQLSWEAQDLCATGVHTGELMVWRYKMSVLPDGLQHHPEATTEARVFLRQMKSGLLLGHELHSPTKFLFVECVRRDPPPSHIPRYIDSYFMKGL
Protein: Neuroplastin (Glycoprotein 55/65) (gp55/65) (Stromal cell-derived receptor 1) (SDR-1) (P97546)
Organism: Rattus norvegicus (Rat)
Function: Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Postsynaptic density {ECO:0000269|PubMed:10759566}.
Interaction partners:
Sequence:
MSGSSLPGALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSLLPVTLQCNLTSSSHTLMYSYWTKNGVELTATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDAMMYCKSVGYPHPEWMWRKKENGVFEEISNSSGRFFIINKENYTELNIVNLQITEDPGEYECNATNSIGSASVSTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKDKNLRQRNTN
Protein: Arginine attenuator peptide (AAP) (CPA1 leader peptide) (P08521)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Arginine attenuator peptide (AAP) that has a regulatory role in the production of arginine-specific carbamoyl phosphate synthetase. Encoded by an upstream open reading frame (uORF) within the 5'-leader region of arginine-specific carbamoyl phosphate synthetase small chain (CPA1) mRNA, it attenuates the translation of the downstream CPA1 ORF. In the presence of high concentrations of arginine, ribosomes translating the uORF encoding AAP stall at the termination codon, resulting in reduced translation from the downstream CPA1 initiation codon.
Interaction partners:
- Carbamoyl phosphate synthase arginine-specific small chain
Sequence:
MFSLSNSQYTCQDYISDHIWKTSSH
Protein: D-xylose reductase [NAD(P)H] (EC 1.1.1.307) (Q2UJW6)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Interaction partners:
Sequence:
MSNGKTFTLSNGVKIPGVGFGTFASEGSKGETYQAVTKALETGYRHLDCAWFYLNEDEVGDGIHDFLKKNPSVKREDIFVCTKVWNHLHRPEDVQWSVDNSLKRLRLDYVDLFLVHWPIASEKEDQEKPKIGPDGKYVILKELTENPEPTWRAMEKIYRDGKAKAIGVSNWTIPGLEKLFKFAEIKPHVNQIEIHPFLPNNELVQFCFKNDILPEAYSPLGSQNQVPTTGERVSENKTLNEIAQKGGNTLAQVLIAWGLRRGYVVLPKSSNPARIESNFKSIELTDEDFEAVNKVAEGRHFRFVNMKDTFGYDVWPEETAKNLSA
Protein: SLIT-ROBO Rho GTPase activating protein 2 (Q5VZB4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
VKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGESQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAEHHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQYIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINK
Protein: Protein ECM27 (Extracellular matrix protein 27) (P47144)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MDWAINVAHPRLLYKDPKLSVTFIVPSLFHIIIAFVLLGICASDFLCPNVAHISDPNSLRSNGSLVSKTASHASHTGALMAVLLSWCNSSPDLFSNLMSWATSTRETRSTSVSLSIGEVLGACGIILCIVEGSIFIIMSRTHIEISQIQKLSIMRDLLFSLAAMCVMSYVSLMNQVTVLNCLLMAFLYAFYLVVKLTFKLNHSAETPDETAADTSLRENSVSPFLDDSLMASGLLPPIQPGFDISNSITHGIKPSLLSAMDFNSFLSMLENSSLEEDDSRNEMAELNTLRSMTPGQHWSASATVAGEATSAGRPFSEPTNAFTEYRDSERAINSSPAVFAPYRDNPDDEESQEQVLLETTTHGHFGAQEMRRFSKRSLGWIIKIFIPHLSNFSQKSISDAIFSIITVPFFIIFKLSCPQPPSDILSYDPTLNRYSLTTLPIILLFIQSITAPFLLCSILSVLLTYHLGYLVYLFPLILAMALILLLTAFITKVNLHNKFTLSLDSSNILQEKLQKRKLLERLNTSIQIIFLAIGIINIIIWISLLANSLIEMMEIYQKILGLSKAILGLTIFAWGNSVGDLISNISMCRLYKTQTHYQDRVRLATKFFMISCASCLGGVMLNSMGGIGFSGLVSMLFIGAFNDNEWWFLRKVKLQETSQLDNTLNYKFIVSCVFIILQIILLLLFFGGPNNIKRRLTKEMKLVGISMCGLWALATLINILLELFS