wanglab/gogpt-training-data huggingface dataset:
Protein: Sad1 and UNC84 domain containing 1 (A0A8I6AQ96)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004540}.
Interaction partners:
Sequence:
MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ
Protein: Nyctalopin (Nyctalopin precursor) (Q00P20)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Transient receptor potential cation channel subfamily M member 1a isoform 1
- Voltage-dependent L-type calcium channel subunit alpha
- Si:cabz01076231.1
- Glutamate receptor, metabotropic 6a
- Calcium-binding protein 4
Sequence:
MCFIINIAVYFLLLPPHALSLWACTRSCPPTCTCTQEKSCSVLCDHVNMMDLPKEFPCEASSINLDKNSLKFLSERAFGTLPSLKTLSLKYNNISFITPGAFKGLPNLVELKMAHNEYIRYLHTRTFTALKRLVRLDLSDCNLFNMPDRIFLEQITLKELLCFQNNFRRVPGALRGMENLTHVYLERNKIEAVAYNSLLGLTSLKYLNLQENRINVIHDEAFKDLIRLENFYLNDNLLVDLPQQAFKGLSNLKMLNLGGNLLTNVSKTWFSDLVELEVLYLDRNRLSYIEDGSFENLTSLITLHLNSNNLTSLPFSVFQPIYFIGRLYLFRNPWECTCDLEWLREWMESYKLVRDIPCASPSSVAGLDLSEVVFAHLNSTCLDPPELNMTTSLPDYPTVENKFNSLISKLLQQELRDEMVNITDSLRNGTQQDPAESQVSSAHGLFGASQTVFLLVVLFQAQFDSINAS
Protein: Protein Wnt (D3ZCR1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
Interaction partners:
- LDL receptor related protein 5
- Protein-serine O-palmitoleoyltransferase porcupine
- Frizzled-8
- NOTUM, palmitoleoyl-protein carboxylesterase
- Cerberus 1, DAN family BMP antagonist.
- Low-density lipoprotein receptor-related protein
- Frizzled-5
- Glypican-3
- Frizzled-1
- Protein wntless homolog
Sequence:
MEPHLLGLLLGLLLSGTRVLAGYPIWWSLALGQQYTSLASQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFHWCCYVSCQECIRIYDVHTCK
Protein: Rearranged L-myc fusion sequence (E9Q532)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MWHLIYYSNFITYLHSYLHCRSCFELLLSVSESELPCEVWVPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPILLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYITCLCSMLPSEEAIQEIAKVDCKDVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDDGKEDKQYRRSLTDQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKELFVPHVMEHVKMPPSRSHRSRKKLLLKSAQRGIYPKSPTGSLEQNPEQARGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVLGCKKFYYSKIEYQNHLSMHNVESPDGELKKSVKLEEPGAGGKQDCVDQSHLLDETEKSHSLEDHHLCPGSASAHIDTTETLKDNSDSNSSDQLSHSSSTSITEELIDTLDHSETMQDLLLSHEKVFVPSSLKDKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKPRKIKTKDLFNCLDDKHNEADKFDAEPKPSSDTNSDSPDEGPDHSIHTKCKREHQGYSPEPSICASKRPCTEDTMLELLLRLKHLSLKNSIAHGSFSGSLQGCPSSGAKSLQSVPSSISDVNLQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFRCHICQRSFTRKTHLRIHYKNKHQIGSDRATHRLLDSEKCDHEGPCSVDRLKGDCSTELGPNSNSETTQCHSKKDECSSETDLESSCEETESKISGISSPIGSHREEGEEKEGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKLFACKYKDCNKRFLCSKALAKHCSDSHNLDHIEESKVLSETESAARFSCNQPQCPAVFYSFSKLKHHLLEQHNIEGEIHSDYEIHCTLNGCGQIFSHRSNYFQHVYYRHKDYYDNLFSSQKVANERLLRSEKVCQTTQAQGLTQTQGQTQGQTQGQEQQAAKRPFNTKAKKCGLLKDKKAPITFKTRAEAIHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMNSAYLEQQLENLVVCVKYGTKIKDEPPSEVEPCVKKEESTSCESVHTENGAPGDSSVPLPNTDSTCPAEQDVGQKGCSERNPVFDTHSLLYRGTLKCNHSSETTSLEQCNIAQSSPCKIESPIPNPSGTESGTYFTDFQLPLPRIKEEPGQHSSGQENTVKNATQVPKENIRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKDDDFDDWEPSEHLTLNNSSHPSNDLTGNVVADTIVNESAPQVDIPHSSSDPPVSENLTAVPPLVVAEATAVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS
Protein: X-linked interleukin-1 receptor accessory protein-like 2 (IL-1 receptor accessory protein-like 2) (IL-1-RAPL-2) (IL-1RAPL-2) (IL1RAPL-2) (EC 3.2.2.6) (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R-9) (IL-1R9) (Three immunoglobulin domain-containing IL-1 receptor-related 1) (TIGIRR-1) (Q9NP60)
Organism: Homo sapiens (Human)
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase delta
Sequence:
MKPPFLLALVVCSVVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLIKWKGSKSSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSAEQGLFGELQPIPSIAMTSTSATLVSSQADLPEFHPSDSMQIRHCCRGYKHEIPATTLPVPSLGNHHTYCNLPLTLLNGQLPLNNTLKDTQEFHRNSSLLPLSSKELSFTSDIW
Protein: BCL2-interacting protein 1a (Vesicle transport protein SEC20) (E9QBD8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}.
Interaction partners:
- Vesicle transport protein USE1
- Vesicle-trafficking protein SEC22b-B
- Vesicle-trafficking protein SEC22b-A
- Syntaxin-18
- RING finger protein 44
- RAD50 interactor 1.
- BCL2-interacting protein 1b
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
- Stanniocalcin 2a.
- Fas-associated factor family member 2.
Sequence:
MAASADVHVRICEQEIIKFDLELKALVQDVNECTGPQSKLTDLNLIVKEKFNKLRQRIQDLEQMGKEQDKESDKLMLLLKVEGHRKQMLSNQTAWRKANLACKLSIDKLEKEDLLNSEDMSVRHRKMTKESLAQTSSDITESLMSISRMMSQQVQQSEETMGTLATSSRTVLETHEEFKAMTGTIQLGRKLIIKYNRRELTDKLLIFLALALFLATVLYILKKRLFPFF
Protein: Alpha-terpineol synthase, chloroplastic (Mg17) (EC 4.2.3.111) (EC 4.2.3.112) (B3TPQ7)
Organism: Magnolia grandiflora (Southern magnolia)
Function: Monoterpene synthase converting geranyl diphosphate into alpha-terpineol. In vitro, can also have an sesquiterpene synthase activity, converting farnesyl diphosphate into (E)-alpha-bisabolene (33.1%), alpha-bisabolene (18.7%), beta-sesquiphellandrene (15.8%), beta-bergamotene (12.6%), (Z)-alpha-farnesene (10.4%), and (Z)-alpha-bisabolene (9.4%).
Subcellular location: Plastid, chloroplast {ECO:0000305|PubMed:18467455}. Note=The transit peptide can target GFP to both chloroplasts and mitochondria when transiently expressed in a heterologous system. {ECO:0000305|PubMed:18467455}.
Interaction partners:
Sequence:
MALKLLFQCSPCSPSSLAPLQPVLVLVRPPSGAKARRNLRCCASTQVTELMTARRSANYHPNIWDYDSVQSLTSDYKAYTYLERVEKLKEDVRRTLQEAVGLLDQLELVDCIHRLGVGYHFDKEIKEILKTISTEPNNMGLIDGDLYAMALYFRLLRQHGYEVPQGVFNRFMDDSSSFKASLCNDVKGMLSLYEASYLALEGETTLDEAKAFTYRHLRGLKGNIDSNLKGLVEHALELPLHWRVLRLEARWYIDTYERMEDMNPLLLELAKLDFNIVQNVYQGQVRKMSGWWKDLGLGQKLGFARDRLMEGFLWTIGVKFEPQFAQCREVLTKINQLITTIDDVYDVYGSLEELELFTKAVDRWDTNAMEELPEYMKICFLALYNTVNEIAYDTLKEQGVDVIPYLQKSWADLCKAYLVEARWYYSGYTPTLDEYLNNAWISIAGPVILVHAYVSMIQMITKEALLDCVGSYESIMQWSSMILRLADDLATSTDELERGDVPKSIQCYMHENTASEVVAREQMRARISDIWKKMNKDVALSPLPQPFKAAAVNLARMAQCMYQHGDGHGNPHRESKDHILSLVVEPIQLMES
Protein: NEDD8 ultimate buster 1 (H3BM74)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKTNGGRCRIRALCWSRREWRGAGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQVLHAASGNLDEALKILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN
Protein: Dexamethasone-induced Ras-related protein 1 (O35626)
Organism: Mus musculus (Mouse)
Function: Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
- Nitric oxide synthase 1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
Sequence:
MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVEQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGDHGDAFGILAPFARRPSVHSDLMYIREKTSVGSQAKDKERCVIS
Protein: Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A) (Q7SYD5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9Z2Q1}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:Q9Z2Q1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9Z2Q1}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z2Q1}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Z2Q1}; Peripheral membrane protein {ECO:0000250}. Note=Associates with membranes in a GTP-dependent manner. Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). {ECO:0000250|UniProtKB:Q3UPL0, ECO:0000250|UniProtKB:Q9Z2Q1}.
Interaction partners:
- Protein SEC13 homolog
- small monomeric GTPase
- Protein transport protein SEC23
- Protein transport protein Sec23A
- Protein transport protein Sec24C
- Protein transport protein Sec24A isoform X2
- small monomeric GTPase
- Protein transport protein Sec24D
- Peflin
- SEC23-interacting protein.
Sequence:
MKLKEINRTAIQAWSPAQQHPIYLAAGTSAQQLDATFSTNASLEIFELDLADSALAMKSCGSFSSPHRYHKLVWGPHGIENQGLPSGVLIAGGENGNIILYDASKIIAGDSEVIISQSEKHTGAVRALDVNSFQSNLVASGGNESEIYIWDLNNFSSPMTPGPKTQPQEDISCVAWNKQVQHILASASPSGKASVWDLRKNDLIIKVSDHSNRMHCSGLAWNPEVATQLVLASEDDRMPVIQMWDLRFATSPLKVLENHTRGILAIAWSVADPELLLSCGKDNRILCWNPNTAEVLYELPTSTQWCFDIQWCPRNPAVLSAAAFDGHISIYSIMGGSNDNANNLQADQLSSSFGNVDPFGTGKTLPPLQLPQQTSPQSTITPLKKPPKWIRRPVGASFAFGGKLVTLDNIKPTAQQPQQTAAHVVHISQVVTETDFIHRSNQLQTTLNAGNFLEYCQNKIETVQNEFERTVWSFLKVNFEEDARLKYLELLGYEKEELALKIASALEGNCKPKEADMDKEEVLAEEEAESDLDDIPVNEEEPVVEETSNTEVPPAPASDAINLKVSQDIDGLITQALLTGDYEAAVNLCLHDNRMADGIILAIAGGPELLAKTQRKYFSKTESKISKLISAVVMKDWLDILETCDLQNWKEALAAVMTYAKPEEFSALCGLLGSRLESSEDVELQAQACLCYICAGTVEQLVSFWTKTQDSCSPLSLQELVEKVVVLQRAVEKAQGAVPADMGALLAEKMNQYASLLASQGSLQTAISYLPTNTEQVSVQQLRERLSRALGQHQHLQQPAAAVTGIQKMHQRRPAAVPMQTYTQPQPPQVPAQPAAPAVPPQYYQQGRSATTVTSWSNQTPTALPSVPRQLVPSSDPQGDSTPPAFGLQSPAMASVPASTPFMYSQQYQNYPPVQQFTPSAGTPGIYQPLPYASSAGAPLPPPPSSSSSAAVYPPQFMLSASSQASAPPQSFCPPPAVSSGGCFQHGGPGSPTSYLPPPGARAPGTQHEPALIPASQRTDGFYQETAWGLEGPQNGWNDPPALSRAAKKKKVPQHFTPPAPITAPIMAPLGDPQAPAGMQTLQPQQQVPDQSAGPATFTPIQQQPLGPRNPSMPQGNMEGAPGAPIGDVIKPLQAIPTEKITKKPIPEEHMVLKTTFEGLIQKCLTAASDPQTKRKLDDAHKRLELLYDKLREQTLSPAIIGGLHNMAQSIECRSYADGLNIHTHIVSNSNFSETSAFMPVLKVVLTQANKLGV
Protein: MIF4G domain-containing protein (C2BR97)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Regulator of nonsense transcripts 1
- UPF3 domain-containing protein
- Serine/threonine-protein kinase smg-1
- RRM domain-containing protein
- RNA-binding protein rnp-4
- PIN domain-containing protein
- Nonsense-mediated mRNA decay protein
- PWI domain-containing protein
- Nonsense-mediated mRNA decay factor SMG9
- Uncharacterized ATP-dependent helicase C05C10.2
Sequence:
MRRKVETSWLEELKKRVKYQETSRLQMVEIRETLLDNEKELRSLDSTLKKTTSFMKKVKLLSAATVPQLIEELSKLNLSKFVEEMASGIIETKLKLSDIPKVTELCLAISAKYSNFSEQMAGEFKKVLPVKKSDKIANVAKLRVDIIFLAELCLCGVFNEKEGLQVLGAVLSYLIQTDKTDFVNVGLLATVSRTVGWQIANIVPIPMDDAETVEIQDEELPESSALSVEQKKSIRELFKSYYDSLYSKTEKTCSARNKAMKRVKRQERSRGDAGDEEKTTLNDLQSELDSLRKMAIEISSAIGVEMKPLKEEASDDEEDEAANLEMGRKLAEGAIKLWSDEETKAFYEDLIDLRQMVPKDLYKESEQRTLSKAKMAERIEDVDMENINESGAMDAKRSSLQRGESEKETTPEDSQLQALLKEAVDASEERGVSKWQSFVLDLDHLVSKYSTDQAAIYFVSNLNNKGCRKRLVKLMIDPPPSRIDVVPFYARLVATLENVMPDLTTEIVTQLLEKFRGFLQQKPSSATAIIKVESKMVCVMMIAELMKFGVISRAEGLSCLRQLVYDLRGHSVEMTATFMESSGLYLYRHTESHAKMKRLLEVVKAKRERMKDQRQAMLIDNAYFTCLPPEDSKEERLRLKLDEEDTPMKRFIRHIILDINESTVDVFLKCLRRLEWYDPEVADYAIRYLSSTWLLPIENLQHVASAIAGLCNLVHLQWIGMAVIDSTIETIRISLENPGVYNQWAHSAAVYLAELYSFELCDEDLVLKILYQLISYPEPENSWRDLHRIRMICAMLEILREFFMKGSGKIKMRYFLSYFHRYYYIKKDAWDQEVAEQQPNSGGETGENQNPLDVQTSFPYEVELAYTELCRQFRQKKSNSLRWPKNLKEAQDIVTKIEKKFKGELKEFAGEHKDIEGDGLNELNVIEEDDEEDEDENRDSELDEDDSEEDRQKIENFSNAVTKEEDDEFQRELDRMMGEGFRQSAFQMPVAAAQYDVTLPAAVKDRFNRSIKFAETVKDEPAASSSKQDNDDDEDVYEKSPTIAASGRQKQTRVTLMVRGKTNKPSLKTVNIDDDQLQERWKEEKAREEQERADMKRLTLGQHRRIEMEEEKALLASLNSSRKGNAKRGQFRPQFPKPHLEGEW
Protein: Protein urg3 (Q9US42)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Uracil-regulated protein 1
- Putative uracil phosphoribosyltransferase urg2
- Uracil phosphoribosyltransferase 2
- Uridine kinase
- Uncharacterized transcriptional regulatory protein C1399.05c
- Probable GTP cyclohydrolase-2
- Inactive zinc metalloprotease C354.09c
Sequence:
MSTETVAKLLSLQDIRYKAQKVLQKAESQSLKSFLYDPSKLPEVADFVVSVIQADFKGKYSTIPPHGRWQHFEVGNVPRLSQLVSKWEKEGVDSLEICKRVLDVTFVSVLLDAGAGDVWKYTDGKEAYGRSEGLAVASLRCFESGLFSSNPDFVYQVDGKALQALTSEKLGAGFQVTEQNPLAGVEGRATILRSLGKQLGSGRPSDFVGRIFPTGDFSKGLNVLELWSELQTLLIPIWPVRTSFEGQNLGDAWYLSTIDAIQPFHKLTQWLTYSLLIPFKSLLKVPVVNEELLTGLPEYRNGGLFVDLGVLTLRPEFSYATEYEPSSVTIVEWRAMTVVLLDKLLAFVNERLKPELSEPLSLAQMLEAGSWKSGRIIAKKLRPSTAGSPILIKSDGTLF
Protein: AAA+ ATPase domain-containing protein (Q38FV5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMENTPLLGREQEYNDVLRFIEERLLIQHCKSLFVFGACGSGKTSTIIRAMRRVTHRVMTYDKAAGRSSTGSNSSNGGGGLSDSPPPAAGRKQQKQMERQRPTKRQRGSETEGNAAGAAAVSADNVKDGHFRSIGNAATPGDPTVLFPHLFGKGRRVQCHYVNCADMTAQQLCDSISETFCSSQVRLDAQTRTLVNAVGGIPKRVSAMRRRSRELLKHYDQQPIEEGLPTAGLTKTTVKTPLHVLVLDEVEYVRAAARGALASLAELSAEYASQLALVFISNQREFVHVPHMLLKELPFEAYSAEMLESIGNHIVAAAHFTRKEKEQVQLSPGLIRYIARKALVEFSGDVRQVAVMCRRLIHTAVEEQKKSVPPKGRVSTEGGETPRGSRELAGATAPGGNSPGVPAALITLAQSQKILRGPDSVGDRVFEYVSAMPEQMLYVLSCLVVLMLRQQRDSQIAKVSIGSTSAVGRRQNKTAIGSSFGSYSAAEPGPVVPGTFTTRVVHRLYTALMGQQRFPSMNAAGISSAIDGFADIGIISRPQRRGNEEVFSFNGTWTLESMQAALTARGEALRQERVDCGLDSAENRFEEVLRELKGILSL
Protein: Transcription factor SOX (Q6P0Z4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR038098}.
Interaction partners:
- Catenin beta-1
Sequence:
MGTDLAMVEQTHTSSSSSSDVLPGDSIDSGEMDLDMDASPTPGSPNSAGDKMDIAWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSSSGKTGEKAERVSASPGAKSASKKSSKTLSRTHRKSTTLELTSHSVPADHHALYKSRSVSAAKQIPEKPAKRGHVYGGCSTDSSPPSVAVPASPTLSSSAESSDPLSLYEDGLASGKEDAEPAARFKYTRAPSPTPSASHSYSSQSSSSDEEFEDELADPSPGFDSFSTFGTAPLDRDLEFNFESGSGSHFEFPDYCTPEVSELMISGDWLESTISNLVFTY
Protein: AFG3 like matrix AAA peptidase subunit 2 (A0A8I5ZLF3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}.
Interaction partners:
Sequence:
MLLFNVMLQLYQYATVQTANSRSSLLRDVIAAYQRFCSRPPKGFEKYFPNGKNGKKASESKEAVGEKKESQLSGPQSSGGASGGGGKRRGKKEDSHWWSRFQKGDFPWDDKDFRMYFLWTALFWSGVMIYFLFKSSGREITWKDFVNNYLSKGVVDRLEVVNKRFVRVTFTPGKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESDGSFLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSALEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDAINEKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISEAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFTEKSTYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEKKEKKEKEEPVNEKVVS
Protein: NURS complex subunit red1 (Q9UTR8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Promotes the exosome-mediated degradation of mRNAs containing a DSR (determinant of selective removal) signal sequence from mitotic cells.
Subcellular location: Nucleus {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:21317872}. Note=Localizes to distinct foci in the nucleus in mitotic cells, which disassemble during meiosis, although the protein is still present.
Interaction partners:
- Uncharacterized protein C7D4.14c
- RNA binding exosome specificity factor Mmi1
- Uncharacterized helicase C17H9.02
- Poly
- Uncharacterized RNA-binding protein C902.04
- Polyadenylate-binding protein 2
- Zinc finger CCCH domain-containing protein C337.12
- NURS complex subunit pir2
- Exosome complex exonuclease rrp6
- Uncharacterized protein C4G9.04c
Sequence:
MSRSINLDELRKKALESKKKNEEDESNDSDKEDGEISEDDPVIDQSNSVPPMKVPTFPEQIPQLPPFDRFPGTNANFFPFGAPFMLPPALMFGPNTVPFFPQTASSNKTFSKRKRSSENSFNNRNKAKSSETSDSSNTSQSFKENRALKDTATSRPLALSSDTSYQKSEKAKSEKSPFLSTSKNSDANYSKTTNQKEAEKAVSQLFEVGVRFNDFIAEGIEPSVVHTLFLKLGLDSSSASSQGSLTLSADKAARSAKLRKIDSNLSDTHILPGDNGTPTVLPERKNLISLPLLKQDDWLSSSKPFGSSTPNVVIEFDSDDDGDDFSNSKIEQSNLEKPPSNSENGLTMSRSDYLALLRNKEEEIRRMTKLILRLESNKKPYRSPTSAADMKLPSVPVAAVDNKSKTHLDTFEKVVDLSSKADFVEAGPSISSSGASSSAATTNSDTTEQILEAPWLRKTEQIAVVHEEHPAQIKKSEIDILNNLIEKEEGELTKYQTLVKSKTEILTQLYTRKKQLLEQQGKGNVACLPKESDLSMDSITEVSAQADENSSQILSSKTSNAPNGTTETDFEDKVPLVDYISPFYRFKSYRFNQQFVERVPLKYRSLTYSNKIEPMKVFCKYETTGGVCNDDHCEASHFRDIKMTDDEIIQDLSRYIEGNDEIEKESYKSGLDIVMKNTDENTDFVDVATRIVEYHNLWKSERMTIPVAKVSI
Protein: Lysyl oxidase homolog 1 (EC 1.4.3.13) (Lysyl oxidase-like protein 1) (LOL) (Q08397)
Organism: Homo sapiens (Human)
Function: Active on elastin and collagen substrates.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:35328709}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P97873}.
Interaction partners:
- Fibulin-5
- Elastin
- Fibrillin-1
- Microfibrillar-associated protein 2
- Latent-transforming growth factor beta-binding protein 2
- Latent-transforming growth factor beta-binding protein 3
- Leukocyte elastase inhibitor
- Microfibrillar-associated protein 5
- Biglycan
- Bone morphogenetic protein 1
Sequence:
MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
Protein: Sucrose nonfermenting 4-like protein (SNF4) (CBS domain-containing protein CBSCBS3) (SNF1-related protein kinase regulatory subunit betagamma) (AKIN subunit betagamma) (AKINbetagamma) (Q944A6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulatory subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, which may play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants.
Subcellular location: Nucleus {ECO:0000269|PubMed:17028154, ECO:0000269|PubMed:21235649}. Cytoplasm {ECO:0000269|PubMed:17028154, ECO:0000269|PubMed:21235649}.
Interaction partners:
- SNF1-related protein kinase catalytic subunit alpha KIN11
- SNF1-related protein kinase regulatory subunit beta-1
- SNF1-related protein kinase regulatory subunit beta-3
- SNF1-related protein kinase catalytic subunit alpha KIN10
- SNF1-related protein kinase regulatory subunit gamma-like PV42b
- SNF1-related protein kinase regulatory subunit gamma-like PV42a
- SNF1-related protein kinase regulatory subunit beta-2
- Phosphoglucan phosphatase DSP4, chloroplastic
- Tubulin-folding cofactor A
- CBS domain-containing protein CBSCBSPB3
Sequence:
MFGSTLDSSRGNSAASGQLLTPTRFVWPYGGRRVFLSGSFTRWTEHVPMSPLEGCPTVFQVICNLTPGYHQYKFFVDGEWRHDEHQPFVSGNGGVVNTIFITGPDMVPAGFSPETLGRSNMDVDDVFLRTADPSQEAVPRMSGVDLELSRHRISVLLSTRTAYELLPESGKVIALDVNLPVKQAFHILYEQGIPLAPLWDFGKGQFVGVLGPLDFILILRELGTHGSNLTEEELETHTIAAWKEGKAHISRQYDGSGRPYPRPLVQVGPYDNLKDVALKILQNKVAAVPVIYSSLQDGSYPQLLHLASLSGILKCICRYFRHSSSSLPILQQPICSIPLGTWVPRIGESSSKPLATLRPHASLGSALALLVQAEVSSIPVVDDNDSLIDIYSRSDITALAKDKAYAQIHLDDMTVHQALQLGQDASPPYGIFNGQRCHMCLRSDSLVKVMERLANPGVRRLVIVEAGSKRVEGIISLSDVFQFLLGL
Protein: Nephrin (Renal glomerulus-specific cell adhesion receptor) (Q9QZS7)
Organism: Mus musculus (Mouse)
Function: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Located at podocyte slit diaphragm between podocyte foot processes. {ECO:0000269|PubMed:10504499}.
Interaction partners:
- CD2-associated protein
- Podocin
- SH2/SH3 adapter protein Nck1
- Kin of IRRE-like protein 3
- Cadherin-3
- Short transient receptor potential channel 6
- Tight junction protein 1
- Kin of IRRE-like protein 1
- Kin of IRRE-like protein 2
- Alpha-actinin-4
Sequence:
MGAKEATVRGPGASPVHRTCHLIPLLLAGMLTTGLAQSPVPTSAPRGFWALSENLTVVEGSTVKLWCGVRAPGSVVQWAKDGLLLGPNPKIPGFPRYSLEGDSAKGEFHLLIEACDLSDDAEYECQVGRSELGPELVSPSVILSILVSPKVLQLTPEAGSTVTWVAGQEYVVTCVSGDAKPAPDIIFIQGGRTVEDVSSSVNEGSEEKLFFTEAEARVTPQSSDNGQLLVCEGSNPALATPIKASFTMNILFPPGPPVIDWPGLNEGHVRAGENLELPCIARGGNPPATLQWLKNGKPVSIAWGTEHAQAVAHSVLVMTVRPEDHGARLSCQSYNSVSAETQERSITLQVTFPPSAVTILGSTSQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLLPTDETVMDGLHGGHISMSNLTLLVKREDNGLSLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPPEGQSIRTGTRVRLVCLAIGGNPEPSLTWLKDSRPVNDPRQSQEPRRVQLGSVEKSGSTFSRELVLIIGPPDNLAKFSCKAGQLSASTQLVVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSLDKEGERLDDVAAKPQSAPFKGSAASRSVFLRVSSRDHGHRVTCRAHSEALRETVSSFYRLNVLYPPEFLGEQVRAVTVVEQGQALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGGALQLWNVTRADDGFYQLHCQNSEGTAEALLKLDVHYAPTIRALKDPTEVNVGGSVDIVCTVDANPILPEMFSWERLGEDEEELNLDDMEKMSKGSTGRLRIRQAKLSQAGAYQCIVDNGVAPAARGLVRLVVRFAPQVDHPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHKYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSVSPHSVGLEWKPGFDGGLPQRFQIRYEALESPGFLYMDVLPAQATTFTLTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSITTPGLDQAPEDTDQPLPTEQPPGPPRLPLLPVLFAVGGLLLLSNASCVGGLLWRRRLRRLAEEISEKTEAGSEEDRIRNEYEESQWTGDRDTRSSTVSTAEVDPHYYSMRDFSPQLPPTLEEVSYRQAFTGIEDEDMAFPGHLYDEVERVYGPPGVWGPLYDEVQMDPYDLRWPEVKYEDPRGIYDQVAADMDAGEPGSLPFELRGHLV