wanglab/gogpt-training-data huggingface dataset:
Protein: DNA-directed RNA polymerase subunit Rpo3 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit D) (mjD) (Q57648)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00320}.
Interaction partners:
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein eL18
- DNA-directed RNA polymerase subunit Rpo10
- DNA-directed RNA polymerase subunit Rpo6
- Small ribosomal subunit protein uS13
- DNA-directed RNA polymerase subunit Rpo5
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS17
Sequence:
MITIKEKRKTRIGEEFIFSLKAPISFSNAIRRIMISEVPTFAIEDVYIYENSSSMDDEILAHRLGLIPIKGKPLLENEVITFTLEKEGPCTVYSSDLKSENGEVAFKNIPIVKLGKGQRIQIECEAIPGIGKVHAKWQPCNAVYKQIADDEVEFFVETFGQMEAEEILEEAVKILKNKAESFLQQLEMIEQ
Protein: 1,8-cineole synthase, chloroplastic (EC 4.2.3.108) (Terpene synthase TPS-Cin) (PgxeTPS-Cin) (F2XF98)
Organism: Picea engelmannii x Picea glauca (Hybrid white spruce)
Function: Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens. Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to 1,8-cineole.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MALVSGAPLASRSCLNKSLISSTHELKPLRRTILPTLRWKSATPSINMCLTTSNSVDAVQRRIANHHSNLWDDDFIQSLSTPYEAPSYRERAERLIGEVKEMFESMGPNNDLLQRLSMVESVERLGIDRHFKNEIKSALDYVYSHWNEKGIGCGRDSVVSDLNSTALALRTLRLHGYPVSSDVLEHFKDQKGRFACSSIKTEGEIRSLLNLFRASLVAFPNEKVMEEAEIFSTTYLKEAVQKIPVSSLSRQIEYNMEYGWHTNLPRLEARNYMGDMIHEMSYMNAEKLLELAKLEFNIFHSLQERELKHLSRWWKDSGFSQLNFVRHRHVEYYTLASCIDIDPKHSAFRLGFAKMCHLITVLDDIYDTFGTMDELKLFTAAIKRWDPSATEWLPEYMKGVYMVVYETVNEMAGEAKKSQGRDTINYARQAWEAYIDSYMKEAEWISSGCLPTFEEYYENGKVSFGYQISVLQPILTLDVPLPHHILQEIIFPSRFNGLASGILRLKGDTRCYQADRARGEEASCISCYMNDNPGATEEDALNHIHAMVNELMKEFNWELLKPDNNVPVSSKKHAFDITRAVHHGYKYRDGYSVANNEIKNLVITTVLEPVPL
Protein: Wilms tumor protein (A0A1W2PQQ0)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
Interaction partners:
Sequence:
LDFLLLQDPASTCVPEPASQHTLRSGPGCLQQPEQQGVRDPGGIWAKLGAAEASAERLQGRRSRGASGSEPQQMGSDVRDLNALLPAVPSLGGGGGCALPVSGAAQWAPVLDFAPPGASAYGSLGGPAPPPAPPPPPPPPPHSFIKQEPSWGGAEPHEEQCLSAFTVHFSGQFTGTAGACRYGPFGPPPPSQASSGQARMFPNAPYLPSCLESQPAIRNQGYSTVTFDGTPSYGHTPSHHAAQFPNHSFKHEDPMGQQGSLGEQQYSVPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLYQMTSQLECMTWNQMNLGATLKGHSTGYESDNHTTPILCGAQYRIHTHGVFRGIQDVRRVPGVAPTLVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKTSEKPFSCRWPSCQKKFARSDELVRHHNMHQRNMTKLQLAL
Protein: Probable pyruvate decarboxylase C186.09 (EC 4.1.1.1) (Q9P7P6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Alcohol dehydrogenase
- Alcohol dehydrogenase 4
- Putative aldehyde dehydrogenase-like protein C922.07c
- Putative aldehyde dehydrogenase-like protein C9E9.09c
- Probable transketolase
- Probable L-lactate dehydrogenase
- Putative S-
- Pyruvate kinase
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Probable S-
Sequence:
MKDNQQAVQLQQPTTIGHYLAVRLAQAGVKHHFVVPGDYNLGLLDKLQYNNYLEEVNCANELNCAFAAEGYARANGIAACVVTYSVGAFTAFDGIGGAYAEDLPVILISGSPNTNDIGSSHLLHHTLGTHDFSYQYEMAKKITCAAVSIQRPTEAPRLIDYAIKMALLKKKPVYIEVPTNVASQPCAAPGPASLITEPETSNQEYLQMAVDISAKIVNGKQKPVLLAGPKLRSFKAESAFLELANSLNCSVAVMPNAKSFFPESHPNYAGIYWGQASTLGAESIINWSDCIICAGTTFTDYSSNGWTSLPPKANVLHVDVDRVTVSDAEFGGVLLRDFLHELAKKVKANNASVVEYKRIRPESLEIPMENPKAALNRKEIIRQVQNLVNQETTLFVDTGDSWFGGMRITLPEKARFEIEMQWGHIGWSVPSAFGYAIGAPKRNVVVFVGDGSFQETVQEVSQMVRLNLPIIMFLINNRGYTIEVEIHDGPYNRIKNWDYAAIVEAFNAGEGHAKGFRVGNGHELAEAIRQAKENSQGPTLIECNIDQDDCSKELINWGHNVGAANGKPPAKE
Protein: Vacuolar segregation protein pep7 (O13786)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for vacuole segregation and vacuole protein sorting. Possibly part of a complex which tethers the vacuole membrane to microtubules, either directly or via kinesin or dynein-like motor proteins. Probably functions in several interorganelle traffic pathways (By similarity).
Interaction partners:
- Vacuolar protein sorting-associated protein 45
- GTP-binding protein ypt5
- GTP-binding protein ypt4
- Syntaxin pep12
- Vacuolar protein sorting-associated protein 27
- 1-phosphatidylinositol 3-phosphate 5-kinase fab1
- Phosphatidylinositol 3-kinase pik3
Sequence:
MQNGKRRIGVRISSNLSNHSGTNLSTSAQSDSSNIVKATECPICGLELPNLSALNDHLDVTHFNDNEKIHKRQDSINSWLTRTLNGASALQMKAAQRLWRMEPYEQNGDSSGAVGLEATKLTDSLVVKNHWQPEVPDMVCHDPMCDKLLNFINGHIHCRKCGYIFCNFHSMYQIKLSIHATYDSENGFWCRVCRECYEGRPGYNDSNGLIRSRFQTFETFRKPLADKRRIEFLRLSKRMKKLEELWTSENVSMLDALLLNKAKRLEQSIVHWQDDSVVQICPECNNSFTLTRRRRHCRLCGRVICRFCVLEISLPQHPQPLLICMSCNQNYFRNVLYQTERSKSLGYIRHIEHLQVFRQAMVNYYRLYEDSLSELLSGEIITEATLKIVKDRRKKFLELCVKYDGTMKKIANHPSSNDAEEQFKQNVVNEAKRYLQETILRLQAIPYHLQVGQAWTSESERELEKKKEQVEKKQEELMQTRIVLEEQVFLVENMIEDAKAKRKFSEVETLLSSLAPLHEEIHSITEKIHDLDLFDI
Protein: Transcription factor MYB123 (Myb-related protein 123) (AcMYB123) (A0A2R6PN00)
Organism: Actinidia chinensis var. chinensis (Chinese soft-hair kiwi)
Function: Transcription activator involved in the spatiotemporal regulation of anthocyanin biosynthesis specifically in the inner pericarp of red-fleshed kiwifruits. Functions in association with BHLH42 to activate the promoters of LDOX (ANS) and F3GT1 that encode the dedicated enzymes for anthocyanin biosynthesis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:30912865}.
Interaction partners:
- Transcription factor BHLH42
Sequence:
MGRSPCCSKEGLIRGAWTAVEDRTLTAYIKAHGEGKWRNLPKRAGLKRCGKSCRLRWLNYLRPDIKRGNISHEEEELIVRLHKLLGNRWSLIAGRLPGRTDNEIKNYWNTTLGKKIRPQTSRESSKNNLTRKSKGKQPVIPPPPSAIRTKAVRCAKLLAPAKSPPTHGPLFLNQPVEKSFAVLEENQSQISKNPLLCVENSHGTEPLEFSFHDQFHHNNGLCLEGLDDHDMVFKDWTASHEFLEVEGNCTLDLESLASLLDCEEWP
Protein: 1-aminocyclopropane-1-carboxylate oxidase 5 (ACC oxidase 5) (AtACO5) (EC 1.14.17.4) (Q0WPW4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Enzyme involved in the ethylene biosynthesis.
Interaction partners:
- 1-aminocyclopropane-1-carboxylate synthase 7
- 1-aminocyclopropane-1-carboxylate synthase 11
- 1-aminocyclopropane-1-carboxylate synthase 8
- 1-aminocyclopropane-1-carboxylate synthase 4
- 1-aminocyclopropane-1-carboxylate synthase 9
- 1-aminocyclopropane-1-carboxylate synthase 5
- 1-aminocyclopropane-1-carboxylate synthase 2
- 1-aminocyclopropane-1-carboxylate synthase-like protein 1
- 1-aminocyclopropane-1-carboxylate synthase 6
- Aconitate hydratase 1
Sequence:
MAIPVIDFSKLNGEEREKTLSEIARACEEWGFFQLVNHGIPLELLNKVKKLSSDCYKTEREEAFKTSNPVKLLNELVQKNSGEKLENVDWEDVFTLLDHNQNEWPSNIKETMGEYREEVRKLASKMMEVMDENLGLPKGYIKKAFNEGMEDGEETAFFGTKVSHYPPCPHPELVNGLRAHTDAGGVVLLFQDDEYDGLQVLKDGEWIDVQPLPNAIVINTGDQIEVLSNGRYKSAWHRVLAREEGNRRSIASFYNPSYKAAIGPAAVAEEEGSEKKYPKFVFGDYMDVYANQKFMPKEPRFLAVKSL
Protein: DNA 3'-5' helicase (EC 5.6.2.4) (A0A1D8PUB1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- DNA repair protein RAD51 homolog
- DNA 3'-5' helicase
- E3 ubiquitin ligase complex SCF subunit
- Proliferating cell nuclear antigen
- DNA-dependent ATPase
- DNA repair and recombination protein RAD52
- Large ribosomal subunit protein mL67
- DNA-dependent ATPase
Sequence:
MELTPTQLDIVNHNYDPQTVLSIQAGPGTGKTFALIKRIQKLIADGVPPQSIVVLSLTNRTVNSLRSALSEYIGGDTGDVVIKTFHSFAFDLIESNLQEYFPEKGRQMLLDDISFQNYRTLFMTGNSVKQLHLEKALSEVREGKDVANVAEKYGISQSDLHETIKFLNDNGMIRYSDFIRDAIELLDVSKGEIVKDIRVLIIDEFQDMQPQLVTFIEKLVEGGNKHITLAGDSNQCIYEFLGSSPDITQKFVSSLGWETEEICLNESFRLTPENLHISNMVIDQNKLVSKKEPSAEPTVYSLVSKYDEYNYIGSEIARLICQSGGLLKFSDFMILASQNREVDSISEFMTNHFGFNVNKYSSNSEWVNSNTHVLIDILSILNKGRGSDLALLCTLMKLGSLKQLIRELYLGYRLSQSTSLEDYLKSESASCKFNSKPRIKFKRQIDLLLNVIEEERKNLGDAVSIMSSLARIVRETDIITYLNKPSRGHKDQENEIKLVNNLTSFYESLSLSYKKTPSLDYFLNNYPEDEPVLEERSINVSTVHKAKGLEFPVVFVTNFPGYFGSANERLLYVALTRAKNLLYTGYQGNTFQAYSSSRGFEMNRTWITNAARDLNRSAPSKHLLNASMRILKTSRLI
Protein: tRNA-uridine aminocarboxypropyltransferase 1 (EC 2.5.1.25) (DTW domain-containing protein 1) (Q8N5C7)
Organism: Homo sapiens (Human)
Function: Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20 in the D-loop of several cytoplasmic tRNAs (acp3U(20)).
Subcellular location: Nucleus {ECO:0000269|PubMed:31804502}.
Interaction partners:
- tRNA-uridine aminocarboxypropyltransferase 2
- 18S rRNA aminocarboxypropyltransferase
Sequence:
MSLNPPIFLKRSEENSSKFVETKQSQTTSIASEDPLQNLCLASQEVLQKAQQSGRSKCLKCGGSRMFYCYTCYVPVENVPIEQIPLVKLPLKIDIIKHPNETDGKSTAIHAKLLAPEFVNIYTYPCIPEYEEKDHEVALIFPGPQSISIKDISFHLQKRIQNNVRGKNDDPDKPSFKRKRTEEQEFCDLNDSKCKGTTLKKIIFIDSTWNQTNKIFTDERLQGLLQVELKTRKTCFWRHQKGKPDTFLSTIEAIYYFLVDYHTDILKEKYRGQYDNLLFFYSFMYQLIKNAKCSGDKETGKLTH
Protein: Collagen, type IX, alpha 3 (A2ACT7)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- Collagen alpha-1
- Collagen alpha-2
- CD44 antigen
- Platelet glycoprotein VI
- Matrilin-3
- Integrin alpha-2
- Integrin alpha-6
- Integrin alpha-3
- Collagen alpha-2
- Collagen alpha-1
Sequence:
MTGAPALALLLLGQLLTATSAQKVGPRGPPGPQGPPGKPGKDGIDGEAGPPGLPGLPGPKGTSGKPGKPGEAGLPGLPGVDGLTGRDGPAGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGLPGGIGLRGPPGPSGLPGLPGLPGPPGPPGNPGVLPEGATDLQCPAICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGSPGPPGPPGIPGTVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGTPGAPGKVGDRGERGPEGFRGPKGDLGRPGPKGIPGMAGPGGEPGMPGKDGKDGVPGLDGEKGEAGRNGGQGEKGPNGLPGLPGRAGSKGEKGEPGRTGELGEAGPSGEPGIPGDVGVPGERGEAGHRGSVGALGPQGPPGAPGIRGFQGQKGSTGDPGLPGPQGLRGDVGDRGPGGATGPKGDQGIAGSDGLPGDKGELGPNGPVGQKGESGSRGELGPKGIQGPNGTSGVQGVPGPPGPLGLQGVQGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGSQGDRGDKGATGAGLDGPAGDQGYQGPQGVPGISKDGRDGAHGEPGLPGDPGLPGAAGAQGTPGICDTSACQGAVLGGGGEKSGPRSS
Protein: Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A) (P42771)
Organism: Homo sapiens (Human)
Function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17658461}. Nucleus {ECO:0000269|PubMed:17658461}.
Interaction partners:
- Nucleophosmin
- E3 ubiquitin-protein ligase Mdm2
- Cyclin-dependent kinase 4
- Cyclin-dependent kinase 6
- Cellular tumor antigen p53
- Myc proto-oncogene protein
- G1/S-specific cyclin-D1
- Cyclin-dependent kinase 2
- GTPase KRas
- GTPase HRas
Sequence:
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD
Protein: Apolipoprotein A-Ia (Apo-AIa) (ApoA-Ia) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I)] (O42363)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).
Subcellular location: Secreted.
Interaction partners:
- Apolipoprotein Ba.
- Apolipoprotein Bb, tandem duplicate 1
- Apolipoprotein C-II
- Apolipoprotein Eb
- Cholesteryl ester transfer protein
- Apolipoprotein A-Ib
- Lecithin-cholesterol acyltransferase.
- Apolipoprotein Bb, tandem duplicate 2.
- Apolipoprotein A-IV a.
- Apolipoprotein C-I
Sequence:
MKFVALALTLLLALGSQANLFQADAPTQLEHYKAAALVYLNQVKDQAEKALDNLDGTDYEQYKLQLSESLTKLQEYAQTTSQALTPYAETISTQLMENTKQLRERVMTDVEDLRSKLEPHRAELYTALQKHIDEYREKLEPVFQEYSALNRQNAEQLRAKLEPLMDDIRKAFESNIEETKSKVVPMVEAVRTKLTERLEDLRTMAAPYAEEYKEQLVKAVEEAREKIAPHTQDLQTRMEPYMENVRTTFAQMYETIAKAIQA
Protein: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16) (P08331)
Organism: Escherichia coli (strain K12)
Function: This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'-cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate.
Subcellular location: Periplasm {ECO:0000269|PubMed:3005231}.
Interaction partners:
- Protein UshA
- Pyrimidine 5'-nucleotidase YjjG
- Uridine kinase
- Adenosine deaminase
- 5'/3'-nucleotidase SurE
- Pyrimidine-specific ribonucleoside hydrolase RihB
- Cytidine deaminase
- Purine nucleoside phosphorylase DeoD-type
- Guanosine-inosine kinase
- Uridine phosphorylase
Sequence:
MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKDTATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDIHPVYKALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDTEVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGADVVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIAKGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARPIYDIANKKSLAAEDSKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQGDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKASGKEVKEWLECSAGQFNQIDPNSTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYDGECQMINANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDENRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKGQYPMNKVATDDIGFAIYQVDLSK
Protein: Glucan endo-1,3-beta-glucosidase 10 (EC 3.2.1.39) ((1->3)-beta-glucan endohydrolase 10) ((1->3)-beta-glucanase 10) (Beta-1,3-endoglucanase 10) (Beta-1,3-glucanase 10) (Putative plasmodesmal associated protein) (AtBG_ppap) (Q9FHX5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plasmodesmal-associated membrane beta-1,3-glucanase involved in plasmodesmal callose degradation and functions in the gating of plasmodesmata.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17270015}; Lipid-anchor, GPI-anchor {ECO:0000255}; Extracellular side {ECO:0000255}. Cell junction, plasmodesma {ECO:0000269|PubMed:17270015}.
Interaction partners:
- PLASMODESMATA CALLOSE-BINDING PROTEIN 1
- Callose synthase 3
- Plasmodesmata-located protein 1
- Plasmodesmata-located protein 5
- Callose synthase 10
- UDP-Glycosyltransferase superfamily protein
- non-specific serine/threonine protein kinase
- Callose synthase 1
- Ankyrin repeat-containing protein At5g02620
- Callose synthase 12
Sequence:
MASSSLQSLFSLFCLALFSLPLIVSSIGINYGQVANNLPPPKNVIPLLKSVGATKVKLYDADPQALRAFAGSGFELTVALGNEYLAQMSDPIKAQGWVKENVQAYLPNTKIVAIVVGNEVLTSNQSALTAALFPAMQSIHGALVDCGLNKQIFVTTAHSLAILDVSYPPSATSFRRDLLGSLTPILDFHVKTGSPILINAYPFFAYEENPKHVSLDFVLFQPNQGFTDPGSNFHYDNMLFAQVDAVYHALDAVGISYKKVPIVVSETGWPSNGDPQEVGATCDNARKYNGNLIKMMMSKKMRTPIRPECDLTIFVFALFNENMKPGPTSERNYGLFNPDGTPVYSLGIKTSSTHSSGSGSSNSTGGSSSGGGGNTGGSSSGGGIYQPVTGNPSPDYMSISSAGGKGRFVECVLFFFLLCIIKLRL
Protein: Transcription initiation factor TFIID subunit 12 (Q5ADM2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription initiation factor TFIID subunit 5
- TATA-box-binding protein
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 2
- SAGA histone acetyltransferase complex subunit
- TAFII55 protein conserved region domain-containing protein
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 13
- TAFII28-like protein domain-containing protein
- Transcription initiation factor TFIID subunit 4
Sequence:
MDSSAASSQEKRVGTSTPEAELNPHRAKALLAKFKEEMALAKAATDPQEREKHSELVEKIKRILIRYQEQQKQAKNNSPATKSNLTNQDSTTNTPSPLATNNNSATNVIEPKTETPDSTPMEQKPIQAPTPQHPNNASTSSATMSTTQFQPQPQPQQQTVTVEKYNHVKNTLKDMWKQVKTLEASSINETQTKKEEIDRKITELRNQMQKYHTAALRMKSKLIEQGTIPANSTPIGSPTPVSNTDPTPIANTTNTSNVTPPTEKAEENSKPNVKPPSTTTTTTSKSKPKPLSTTATNSTTKTSTPSKGSGSSKSNNRSSSQNTPGTSTSASATKTASVSTEKDAPLTATTSTSAVAPAAATVAATTAPTAAAAATSLSTASAITTKSTADPKVTPSNIPDNDGRVLTKRKLVEMINNISIDQGDAKIPIDNDVEDIFLDLADEFVRNVVQFSGRLAKHRKLDRIDVRDVQLNLERNWGLRIPGYSTDEIRAARKWQPEGEYAENVKKISKLNKDQ
Protein: Vesicular GABA transporter (Uncoordinated protein 47) (Protein unc-47) (P34579)
Organism: Caenorhabditis elegans
Function: Involved in the uptake of GABA into the synaptic vesicles.
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000269|PubMed:9349821}; Multi-pass membrane protein {ECO:0000269|PubMed:9349821}.
Interaction partners:
- Glutamate decarboxylase 1
- Vesicular acetylcholine transporter unc-17
- Lysosome-associated membrane glycoprotein 5
- Ras-related protein Rab-3
- Gamma-aminobutyric acid receptor subunit beta
- J domain-containing protein
- Homeobox protein unc-30
- Heat shock protein hsp-1
- Probable vesicular glutamate transporter eat-4
- Transporter
Sequence:
MASNRFQNLQNWTNKHVFSNSLDYWNQELNEVPSYQNQPQTGESGSNPPPHDRLEPIQESVVSEQPQKDDINKQEEAKDDGHGEASEPISALQAAWNVTNAIQGMFIVGLPIAVKVGGWWSIGAMVGVAYVCYWTGVLLIECLYENGVKKRKTYREIADFYKPGFGKWVLAAQLTELLSTCIIYLVLAADLLQSCFPSVDKAGWMMITSASLLTCSFLDDLQIVSRLSFFNAISHLIVNLIMVLYCLSFVSQWSFSTITFSLNINTLPTIVGMVVFGYTSHIFLPNLEGNMKNPAQFNVMLKWSHIAAAVFKVVFGMLGFLTFGELTQEEISNSLPNQSFKILVNLILVVKALLSYPLPFYAAVQLLKNNLFLGYPQTPFTSCYSPDKSLREWAVTLRIILVLFTLFVALSVPYLVELMGLVGNITGTMLSFIWPALFHLYIKEKTLNNFEKRFDQGIIIMGCSVCISGVYFSSMELLRAINSADS
Protein: Mad2 (RE72064p) (Q9VRQ2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Monopolar spindle 1, isoform B
- Bub1-related kinase
- Mitotic checkpoint protein BUB3
- Cell division cycle protein 20 homolog
- FI09619p
- Bub1 kinase, isoform A
- Cell division cycle protein 27 homolog
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 10
- Cell division cycle 16
Sequence:
MSTAQATKNCITLKGSAQIIVEYLKYGINSILFQRGIYPAEDFNNTQQYGLTILMSKDPKIKTFLQNVLSQTEEWLSKNMINKISMVITNAHTKEVLECWDFNMQAELGDGDISDPTKATTTKELSRIQNEIRDVMRQISATVSYLPLLDCICTFDIMIHTLQNTELPAKWDETGAIVIQNPQAVQLRSFSTGLHKVDTVVNYKMST
Protein: 1-aminocyclopropane-1-carboxylate synthase 8 (ACC synthase 8) (EC 4.4.1.14) (S-adenosyl-L-methionine methylthioadenosine-lyase 8) (Q9T065)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: 1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes catalyze the conversion of S-adenosyl-L-methionine (SAM) into 1-aminocyclopropane-1-carboxylate (ACC), a direct precursor of ethylene.
Interaction partners:
- 1-aminocyclopropane-1-carboxylate oxidase 4
- 1-aminocyclopropane-1-carboxylate oxidase 1
- 5'-methylthioadenosine nucleosidase
- 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
- S-adenosylmethionine synthase 1
- 1-aminocyclopropane-1-carboxylate oxidase 5
- 1-aminocyclopropane-1-carboxylate oxidase
- 1-aminocyclopropane-1-carboxylate oxidase 3
- 1-aminocyclopropane-1-carboxylate oxidase 2
- S-adenosylmethionine synthase 4
Sequence:
MGLLSKKASCNTHGQDSSYFWGWEEYEKNPYDEIKNPDGIIQMGLAENQLSFDLIESWLAKNPDAANFQREGQSIFRELALFQDYHGLPSFKNAMADFMSENRGNRVSFNPNKLVLTAGATPANETLMFCLADPGDAFLLPTPYYPGFDRDLKWRTGAEIVPIQCKSANGFRITKVALEEAYEQAQKLNLKVKGVLITNPSNPLGTTTTRTELNHLLDFISRKKIHLISDEIYSGTVFTNPGFISVMEVLKDRKLENTDVFDRVHIVYSLSKDLGLPGFRVGVIYSNDDFVVSAATKMSSFGLISSQTQYLLSALLSDKTFTKNYLEENQIRLKNRHKKLVSGLEAAGIECLKSNAGLFCWVDMRHLLKSNTFEAEIELWKKIVYEVKLNISPGSSCHCNEPGWFRVCFANLSEETLKVALDRLKRFVDGPSPTRRSQSEHQRLKNLRKMKVSNWVFRLSFHDREPEER
Protein: BTH-induced ERF transcriptional factor 4 (Q5MFV0)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MCGGAILAELIPSAPAARRVTAGHVWPGDANKAKKKGARADDFEAAFRDFDNDSDDEEMMVEEAEEEEATSEHKPFVFRAKKAAAAASSRRRKPAQYRGVRRRPWGKWAAEIRDPVKGIRVWLGTFTNAEAAALAYDDAARAIRGDRAKLNFPSATTPDTRKRGRATAAAAPAVKATPVINLVEEEDEEEVAAAMASIKYEPETSESSESNALPDFSWQGMSASDEFAVAAAALSLDSDDDLAKKRPRTEPEDTTDSGSGDDTDALFDALLFADQYNHFNGGAYESLDSLFSADAVQTTAAAAAADQGMGLWSFDDGCCLVDVEASLSF
Protein: ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125) (Q86XP3)
Organism: Homo sapiens (Human)
Function: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19377511}. Nucleus {ECO:0000269|PubMed:16397294, ECO:0000269|PubMed:19377511}.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus, Cajal body {ECO:0000269|PubMed:12234937}. Nucleus speckle {ECO:0000269|PubMed:12234937}.
Interaction partners:
- Splicing factor 3B subunit 1
- Splicing factor 3A subunit 2
- Splicing factor 3B subunit 3
- Splicing factor 3B subunit 5
- PHD finger-like domain-containing protein 5A
- Splicing factor 3B subunit 4
- Splicing factor 3B subunit 2
- ATP-dependent RNA helicase DHX15
- Splicing factor 3B subunit 6
- Splicing factor 3A subunit 1
Sequence:
MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFYKIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS
Protein: Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2) (P0CW70)
Organism: Mus musculus (Mouse)
Function: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:22764053, ECO:0000269|PubMed:34471926}; Multi-pass membrane protein {ECO:0000305}. Note=Restricted to the inner nuclear membrane facing the acrosomal vesicle. The N- and C-termini are oriented towards the nucleoplasm (PubMed:22764053). Colocalizes with FAM209 at the inner nuclear membrane (PubMed:34471926). {ECO:0000269|PubMed:22764053, ECO:0000269|PubMed:34471926}.
Interaction partners:
- Spermatogenesis-associated protein 16
- Zona pellucida-binding protein 1
- Sperm acrosome membrane-associated protein 1
- PRKCA-binding protein
- Golgi-associated PDZ and coiled-coil motif-containing protein
- SUN domain-containing protein 5
Sequence:
MVGPTRSKLREGSSDRPQSSCTGQARRRWSAATMEPQQERSAPQERTKWSLLQHFLLGGRKLPSGARNYAARRIQSLNAQNYFQLEEVAKLLLLNRFQFLFTLLDHFREKVQALQMHRFSHRTLFGLAIFVGILHWLHLITLFENDHHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLVINTVKRFHLYPEVVIAYWYRTIIGIMNLFGIETKTCWNVTRMEPLNEVQSCEGLGDPACFYIGVIFILNGLMMGLFFIYSTYLSGSQLGGLITVACYFFNHGEATRVMWTPPLRESFSYPFLVLQMYILTIILRTSTVHKKHYMALCFSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYVNMSSVALCFILMFGNSMYLSSYYSSCLLVTWAIMQKKSKIQKLGGTELQFWLIQGCFWWCGTIILKFLTSKICGVSDHIRLSDLIAARILRYTDFDTLIYTCAPEFDFMEQATPLRYIKTLLLPLILVITYLIFKKIVRDIMCVLYTNTYVRKQLLDNAELIFHTLQLLAFTGLAILIMRLKLFLTPHMCIMASLICSQRLFGWLFCRIHFENVVFGILTMMSIQGCANLHNQWSIMGEFTNLPQEELIHWIKHSTRPDAVFAGAMPTMASIKLSTLRPIVNHPHYEDADLRARTKIVYSVYSRKSAVEVRNNLLKLHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSILLKDSRPYFTTVFQNSMYRVLKIN