wanglab/gogpt-training-data huggingface dataset:
Protein: Thioredoxin domain-containing protein C959.05c (EC 5.3.4.1) (Putative protein disulfide isomerase C959.05c) (Q9P4X1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as a membrane-bound chaperone in endoplasmic reticulum quality control. Probably facilitates presentation of substrate to membrane-bound components of the degradation machinery (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative protein disulfide-isomerase C1F5.02
- ERO1-like protein 2
- Thioredoxin domain-containing protein C13F5.05
- Uncharacterized protein C3D6.13c
- ERO1-like protein 1
- Protein disulfide-isomerase C17H9.14c
- Tryptophan synthase
- Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2
Sequence:
MKLFLYHFTFIVYYFIISFSYAFSIKQEIIVSSHNASSILNTTAFWFVEFTESKYDKEEFSVIWNEVSMEFPDIRRAKVFCDLDLEFCAQQEIYDHPKVVVLKNGMWMRHVLEKNQITTKSARQFVKSHLGNCDLEQAENETDCFSDDGEYNSDSSSTDPAFELKEDQSWKHSSILRPLETLNFKRFLFGNEIMSKTRAFVMFVSLKHCEDCFHWEAVWSSITRNTDERLKMAQVNCDEEKEMCNHFHIKKFPTFRVFQGFDSIQYNGPLKYQQLLSYSNQVASYQAIKIEEGDIESIENSHPVFFLVLYDFATTSEDFSIIERLKLQLAGVAPLYICNSKALANKYGAQSQPSIIAVRNGMPIVYQAITPREFRDYKRITEWINIVSSPFITELTPTKCHSLLNRKLTVLTLLQPDSEQFFSSQEELLRLGKRWFRFQMQRQRNDIVWSRIKKYSAIAEAKKKGFARKVKRIKYSKISHPTYTESVSFLWLDSSLWLDWIVENLDHTVYVDSITPPVFVIDHSKGVIYVSDRNGNSLTLEEDSLFSTLRIILEHPNSSRLQKLRAPGLCPNGSPNYRNRYKLIVFNLLIALLILSILTIISASRLSRRRRQLLNKQPVFGFYHSLVIAKSD
Protein: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4) (DNA N6-methyl adenine demethylase ALKBH4) (EC 1.14.11.51) (Lysine-specific demethylase ALKBH4) (EC 1.14.11.-) (Q9NXW9)
Organism: Homo sapiens (Human)
Function: Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA, thereby regulating Polycomb silencing (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17979886}. Nucleus {ECO:0000269|PubMed:17979886, ECO:0000269|PubMed:23145062}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9D8F1}. Midbody {ECO:0000269|PubMed:23673617}. Note=Associates with the contractile ring and midbody. {ECO:0000269|PubMed:23673617}.
Interaction partners:
- Nucleic acid dioxygenase ALKBH1
- 2-oxoglutarate and iron-dependent oxygenase JMJD4
- Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial
- Probable RNA/DNA demethylase ALKBH6
- DNA oxidative demethylase ALKBH2
- tRNA
Sequence:
MAAAAAETPEVLRECGCKGIRTCLICERQRGSDPPWELPPAKTYRFIYCSDTGWAVGTEESDFEGWAFPFPGVMLIEDFVTREEEAELVRLMDRDPWKLSQSGRRKQDYGPKVNFRKQKLKTEGFCGLPSFSREVVRRMGLYPGLEGFRPVEQCNLDYCPERGSAIDPHLDDAWLWGERLVSLNLLSPTVLSMCREAPGSLLLCSAPSAAPEALVDSVIAPSRSVLCQEVEVAIPLPARSLLVLTGAARHQWKHAIHRRHIEARRVCVTFRELSAEFGPGGRQQELGQELLRIALSFQGRPV
Protein: Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] (Q9NQX3)
Organism: Homo sapiens (Human)
Function: Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors.
Subcellular location: Postsynaptic cell membrane {ECO:0000269|PubMed:25025157, ECO:0000269|PubMed:26613940}; Lipid-anchor {ECO:0000269|PubMed:25025157}; Cytoplasmic side {ECO:0000305|PubMed:25025157}. Cell membrane {ECO:0000250|UniProtKB:Q03555}; Lipid-anchor {ECO:0000250|UniProtKB:Q03555}; Cytoplasmic side {ECO:0000250|UniProtKB:Q03555}. Cytoplasm, cytosol {ECO:0000269|PubMed:25025157}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q03555}. Cell projection, dendrite {ECO:0000269|PubMed:26613940}. Postsynaptic density {ECO:0000250|UniProtKB:Q8BUV3}. Note=Cytoplasmic face of glycinergic postsynaptic membranes (By similarity). Forms clusters at synapses (PubMed:25025157). {ECO:0000250|UniProtKB:Q03555, ECO:0000269|PubMed:25025157}.
Interaction partners:
- Rho guanine nucleotide exchange factor 9
- Molybdopterin synthase catalytic subunit
- Glycine receptor subunit beta
- Molybdenum cofactor biosynthesis protein 1
- Neuroligin-2
- Glycine--tRNA ligase
- Vesicular inhibitory amino acid transporter
- Gamma-aminobutyric acid receptor-associated protein
- Profilin-1
- Sulfite oxidase, mitochondrial
Sequence:
MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
Protein: BHLH family protein, putative, expressed (Os10g0403800 protein) (Q8LNC7)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MSGRRASGRITDDEINELISKLQSLLPESSRRRGATSRSPATKLLKEMCSYIKSLHREVDDLSERLSELMATMDSNSPQADIIRSLLR
Protein: Myelin proteolipid protein (Lipophilin) (Q78EF6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Myelin membrane {ECO:0000256|ARBA:ARBA00037844}.
Interaction partners:
Sequence:
IHAFQCVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSAT
Protein: Coiled-coil domain-containing protein 42 (Q5SV66)
Organism: Mus musculus (Mouse)
Function: Required for sperm development.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000269|PubMed:31475146}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:31475146}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:31475146}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:31475146}. Note=Weakly expressed in the cytoplasm of round spermatids. In elongating spermatids, localizes to the manchette microtubules and the perinuclear ring. In the sperm flagellum, strongly expressed in the principle piece and also located to the connecting piece and weakly to the midpiece. Localizes to the centrosome in somatic cells. {ECO:0000269|PubMed:31475146}.
Interaction partners:
- Coiled-coil domain-containing protein 38
- Outer dense fiber protein 1
Sequence:
MSLGMMEEEDLAEYFRLQYGERLLQLLQKFPNVEEQSDSPSIQLLEKKKEAKIMQEAMEHKKEAFQRRMETLNLRWEELGIKEEQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRLRLRELAKAKQEMMALRLEHQKLSVKLQDYAIFNKYLEKVVENSEFEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQHNNELARLQMRFDRARSDVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKQLKESTQVSLEDTHKQLDMIQQFIQDLSDIWTEVKKKEQQQVRM
Protein: Protein ripply3 (XRipply3) (Down syndrome critical region protein 6 homolog) (B7XDF1)
Organism: Xenopus laevis (African clawed frog)
Function: Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of tbx1 that plays a key role in pharyngeal development. Plays a role in the formation of the anteroposterior (AP) axis during embryonic development; required to establish the posterolateral border of the pre-placodal ectoderm (PPE) acting downstream of the retinoic acid receptor (RAR) signaling.
Subcellular location: Nucleus {ECO:0000269|PubMed:19247927}.
Interaction partners:
Sequence:
MDSSQYMLKATLTQMCLCSRGVRNVHSEHPQQQDSSLTLWRPWLLGAGDRELDGQQRRSGEADGVPTNTGPKGALGFQHPVRLYMPKSKTSEYLQHMGRKVLASFPVQATIHFYNDDSDSEEEDEEEEMEFYNYYQNCAANGVDSSRGSSDNYSVQGGPKRNIGSHAGSA
Protein: (thale cress) hypothetical protein (A0A178UTG1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGGGKDKHHDEQEKGFHGFPGGGHYPPAQGGYPPQGYPPQQGYPPAGGYPPAGYPPGAYPAAPGGYPPAPGGYPPAGYPAPGAHHSGHSGGGLGGMIAGAAGAAAAAYGAHHVGHASHNPYGHAVGHGGYGHAPAHGFGHGGHGKFKHGKHGGKFKHGKHGKHGKHGMFGGGGKFKKWK
Protein: Proteinase-activated receptor 1 (PAR-1) (Thrombin receptor) (P30558)
Organism: Mus musculus (Mouse)
Function: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P26824}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P26824}.
Interaction partners:
- Prothrombin
- Guanine nucleotide-binding protein subunit alpha-12
- Guanine nucleotide-binding protein subunit alpha-13
- Vitamin K-dependent protein C
- Guanine nucleotide-binding protein G
- Lysophosphatidic acid receptor 1
- Beta-arrestin-2
- Beta-arrestin-1
- Angiotensinogen
- Lysophosphatidic acid receptor 2
Sequence:
MGPRRLLIVALGLSLCGPLLSSRVPMSQPESERTDATVNPRSFFLRNPSENTFELVPLGDEEEEEKNESVLLEGRAVYLNISLPPHTPPPPFISEDASGYLTSPWLTLFMPSVYTIVFIVSLPLNVLAIAVFVLRMKVKKPAVVYMLHLAMADVLFVSVLPFKISYYFSGTDWQFGSGMCRFATAAFYGNMYASIMLMTVISIDRFLAVVYPIQSLSWRTLGRANFTCVVIWVMAIMGVVPLLLKEQTTRVPGLNITTCHDVLSENLMQGFYSYYFSAFSAIFFLVPLIVSTVCYTSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIVCFGPTNVLLIVHYLFLSDSPGTEAAYFAYLLCVCVSSVSCCIDPLIYYYASSECQRHLYSILCCKESSDPNSCNSTGQLMPSKMDTCSSHLNNSIYKKLLA
Protein: histone acetyltransferase (EC 2.3.1.48) (A0A8C0NLP0)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVRKTLDLSLQPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
Protein: Probable GTP diphosphokinase CRSH, chloroplastic (EC 2.7.6.5) (Calcium-activated RelA/Spot homolog) (AtCRSH) (ppGpp synthetase CRSH) (Q84R11)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses calcium-dependent ppGpp (guanosine 3'-diphosphate 5'-diphosphate) synthetase activity in vitro and is able to functionally complement E.coli relA mutants. Plays an important role in the timing adjustment of pistil and pollen maturation required for successful pollination. May be involved in a rapid plant ppGpp-mediated response to pathogens and other stresses.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:18178586}.
Interaction partners:
- Nucleoside diphosphate kinase 1
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase II, chloroplastic
- Inosine triphosphate pyrophosphatase
- Alkaline-phosphatase-like family protein
- Large ribosomal subunit protein bL31c
- Large ribosomal subunit protein bL28c
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Mitochondrial substrate carrier family protein
Sequence:
MSVIRPSPIPIPRCRSQVLHRRLYSIQLIQRRRRRWNPRSEVEDTAIESTARSPEAAGGKMVVELVGAFNEVTERMNSVWLSTSSSRLLFKALKLSIPILQSLPLASDGRSPLSKALSLSIILADLQMDAEVISASILSEVVDANAISIYEVRDHIGTGTAHLLHEIFRVKNIPFKVDVLDDETAASLRKFYLTYYDIRAVIMDLVSKLDEMRHLDHLPRYRQQILSLEVLKIYSPLAHAVGANHLSLELEDISFRYLFPCSYIYLDSWLRGHENGSKPLIDVYKEQLHRSLKDDLVLAEMVNDVYIKGRYKSRYSMMKKLLRDGRKPEEVNDVLGLRVILMPNSVVNDVEVGEKACYRTSEIIRSLWKEIPHRTKDYIARPKENGYRSLHMAVDVSDSDQIRPLMEIQIRTMDMDGSANAGTASHSLYKGGLTDPKEAKRLKAIMLAAADLAAIRLKDISSNKHQSFKTTTNQRDRVFCLLDKNGDGMISIEELMEVMEELGAPGEDAEEMMQLLDSNSDGSLSSDEFDTFQKQVEFMRKWEDRDNEYKSLLDEKLHDLPHQDTTGLIQLYNKELEDRLSTH
Protein: ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (P38817)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May play a role in the regulation of membrane traffic through the trans-Golgi network.
Subcellular location: Golgi apparatus, trans-Golgi network.
Interaction partners:
- Epsin-3
- Epsin-5
- Clathrin heavy chain
- AP-1 complex subunit gamma-1
- Mannose 6-phosphate receptor-like protein 1
- Polyubiquitin
- ADP-ribosylation factor-binding protein GGA1
- ADP-ribosylation factor 1
- Polyphosphatidylinositol phosphatase INP53
- Vacuolar protein sorting/targeting protein VPS10
Sequence:
MSHPHSHSIYLSELPVRKPQALGNPLLRKIQRACRMSLAEPDLALNLDIADYINEKQGAAPRDAAIALAKLINNRESHVAIFALSLLDVLVKNCGYPFHLQISRKEFLNELVKRFPGHPPLRYSKIQRLILTAIEEWYQTICKHSSYKNDMGYIRDMHRLLKYKGYAFPKISESDLAVLKPSNQLKTASEIQKEQEIAQAAKLEELIRRGKPEDLREANKLMKIMAGFKEDNAVQAKQAISSELNKLKRKADLLNEMLESPDSQNWDNETTQELHSALKVAQPKFQKIIEEEQEDDALVQDLLKFNDTVNQLLEKFNLLKNGDSNAASQIHPSHVSAPLQQSSGALTNEINLIDFNDLDEAPSQGNNNTNGTGTPAAAETSVNDLLGDLTDLSISNPSTANQASFGLGGDIVLGSSQPAPPVTTTNNSNNTLDLLGLSTPQSPTNSQAVNSSGFDLLMGFNPTTGTTTAPARTLVNQSPNLKIEFEISRESNSVIRIKSFFTNLSSSPISNLVFLLAVPKSMSLKLQPQSSNFMIGNAKDGISQEGTIENAPANPSKALKVKWKVNYSVNSTQAEETAVFTLPNV
Protein: Receptor protein-tyrosine kinase (EC 2.7.10.1) (E7CXR9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MRPSGTARTKLLLLLAALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAVLSNYGTNKTGLRELPMRNLQEILIGAVRFSNNPILCNMETIQWRDIVQDVFLSNMSMDVQRHLTGCPKCDPSCPNGSCWGRGEENCQKLTKIICAQQCSRRCRGRSPSDCCHNQCAAGCTGPRESDCLVCHRFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGVSKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPENWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKATNHVCNPLCSSEGCWGPEPTDCVSCQNVSRGRECVDKCNILEGEPREFVENSECIQCHPECLPQTMNITCTGRGPDNCIKCAHYVDGPHCVKTCPSGIMGENNTLVWKFADANNVCHLCHANCTYGCAGPGLKGCQQPEGPKIPSIATGIVGGLLFIIVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETKFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMEEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSANSNSSTVACINRNGSCRVKEDAFLQRYSSDPTSVLTEDNIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVSNPEYLNTAQPTCLSSGFDSSALWIQKGSHQMSLDNPDYQQDFFPKEAKPNGIFKGPTAENAEYLRVAPPSSEFIGA
Protein: Uncharacterized protein (Q389K0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- MI domain-containing protein
- Peptidyl-prolyl cis-trans isomerase
- Pre-mRNA splicing factor, putative
- peptidylprolyl isomerase
- Splicing factor YJU2
- G10 protein
- ATP-dependent DEAD/H RNA helicase, putative
- Peptidyl-prolyl cis-trans isomerase
- RNA helicase
- Uncharacterized protein
Sequence:
MGSILCAGGECGSLCFWDFASPLKSRSVNPTRILTPFPNRISGFQAVISVHSACDGSYFVACQDGDSPVLVAANGKQLGYCSMGERGMVDVVKCKGHRGPVTSSAPSPTLASRFFTGSQDSTARVWDAASFETNSVYAVKHGSGQLLENVVVESVLPLLSVGSDKTCVFASGGEDGLVQLWDSRLKYRPGGVFSVLDMYGSGGLSSSSCGSSHGRRTAHDTFSEERHVGGMAEPDPTYPTLCVRCGPLVRIVDLRNPAKSGTVVDVCPPLTGLPSSTDTGPLVTCTSESFSKGKPSFIACTSRSGYQHIAGGHIVQFTCTSGNYEPSMVWRPASADADVVAVAVDATQQQLFAGTQNGTVVARIKCTGTDVAVAGPNVQTWFGSRPMSEPGMVRQKRGRAEGNCDDGDELRL
Protein: Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO) (P31146)
Organism: Homo sapiens (Human)
Function: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Note=In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity). {ECO:0000250}.
Interaction partners:
- Cofilin-1
- Cofilin-2
- Coronin-1B
- FYVE, RhoGEF and PH domain-containing protein 3
- Actin nucleation-promoting factor WAS
- Integrin beta-2
- Intraflagellar transport protein 80 homolog
- Lysosomal-associated transmembrane protein 5
- Neutrophil cytosol factor 4
- Actin-related protein 2
Sequence:
MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPEASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
Protein: Sigma-54 dependent transcriptional regulator/response regulator (Q72DI3)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- histidine kinase
- histidine kinase
Sequence:
MANRQRVLLVDDEQDFANGLARLIARLFPDVHVDVAFSGQDALEHIRKQRVHVMVTDLRMPGMGGMELLRRVMETEPDVSVVVLTAHGTIETAVEALQAGAYDFVTKPVEPEQVARVLRKGLERARLLDENRRLRDLVALVGESGELVGESPAMQSVRRTVATVAPSDYTVLIRGESGTGKEMVARMVHRLSPRVDEPFLALNCPAIPEHLLESELFGHVRGAFTGAERDRKGLFSIADGGTVLLDEIGDISSNIQTKLLRFLQEGEVRPVGSPRNEHVDVRIIASTNQDLEARMASRDFREDLFYRLNVVTIWVPPLRERLSDIPLLAATFLARASRELGVPQRDFDEGVLDHLMRREWPGNVRELQNYVRRLALFSRGDGITLDAVQQAEQSESGAPAALCVPSPVAEGEVMPYKDAKASLVESFSERYLRDLLESTGGNVTEAARLSGLSRVSIQKMVARYGIDAAAMRANGS
Protein: Cleavage stimulation factor subunit 3 (F1M4W7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Cleavage stimulation factor subunit 1
- Cstf2 protein
- Pre-mRNA cleavage complex 2 protein Pcf11
- Symplekin
- Cleavage and polyadenylation specificity factor subunit 1
- Cleavage stimulation factor subunit 2, tau variant.
- WD repeat domain 33
- Pre-mRNA 3'-end-processing factor FIP1
- Cleavage and polyadenylation specificity factor subunit 3
- Cleavage and polyadenylation specificity factor subunit 2
Sequence:
MSGDAAAEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDARTRHHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFREEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVRIITGGAPELAVEGNGPVESSAVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR
Protein: BarH-like 2 homeobox protein (Q9NY43)
Organism: Homo sapiens (Human)
Function: Potential regulator of neural basic helix-loop-helix genes.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQPPPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSSPIPGTPHPR
Protein: Gamma carbonic anhydrase 1, mitochondrial (AtCA1) (GAMMA CA1) (EC 4.2.1.-) (Q9FWR5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration (By similarity).
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:15604675}; Peripheral membrane protein {ECO:0000269|PubMed:15604675}; Matrix side {ECO:0000269|PubMed:15604675}. Note=Probably integral to the membrane. {ECO:0000250}.
Interaction partners:
- Gamma carbonic anhydrase-like 2, mitochondrial
- Gamma carbonic anhydrase 2, mitochondrial
- 2Fe-2S ferredoxin-like superfamily protein
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Excitatory amino acid transporter
- Uncharacterized protein At2g27730
- At4g16450
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase iron-sulfur protein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8-A, mitochondrial
Sequence:
MGTLGRAFYSVGFWIRETGQALDRLGCRLQGKNYFREQLSRHRTLMNVFDKAPIVDKEAFVAPSASVIGDVHIGRGSSIWYGCVLRGDVNTVSVGSGTNIQDNSLVHVAKSNLSGKVHPTIIGDNVTIGHSAVLHGCTVEDETFIGMGATLLDGVVVEKHGMVAAGALVRQNTRIPSGEVWGGNPARFLRKLTDEEIAFISQSATNYSNLAQAHAAENAKPLNVIEFEKVLRKKHALKDEEYDSMLGIVRETPPELNLPNNILPDKETKRPSNVN
Protein: NAD(P)H-quinone oxidoreductase chain 4, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase, chain 4) (NADH-plastoquinone oxidoreductase chain 4) (P0C325)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, putative, expressed
- Cytochrome c oxidase subunit 3
Sequence:
MSSFPWLTILVVLPIFAGSLIFFLPHRGNKIVRWYTMSICLLEFLLMTYAFCYHFQLEDPLIQLKEDSKWIDVFNFHWRLGIDGLSLGSILLTGFMTTLATLAAWPVTRNSRLFYFLMLAMYSGQIGLFSSRDLLLFFIMWELELIPVYLLLSMWGGKRRLYSATKFILYTAGGSIFFLIGVLGMGLYGSNEPRLDLERLINQSYPATLEILFYFGFLIAYAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLIRINMELLPHAHYLFSPWLVIIGAMQIIYAASTSLGQRNFKKRIAYSSVSHMGFIIIGIGSITNIGLNGAILQILSHGFIGATLFFLAGTACDRMRLVYLEELGGVSIPMPKIFTMFSSFSMASLALPGMSGFVAELVVFFGLITSPKFLLMPKMLITFVMAIGMILTPIYLLSMLRQMFYGYKLFHVPNENFEDSGPRELFLLICIFLPVIGIGIYPDFVLSLSVDRVEALLSNYYPK