wanglab/gogpt-training-data huggingface dataset:
Protein: Rap guanine nucleotide exchange factor 1 (A0A8I5ZRV1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSQKEKRPGPHVPSFDSFKKEVLAKRPHHSHKNHSLSCPSSNSQTSVLSDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSKTPEKPVSKEARDRFLPEGYPIPLDLEQQAVEFMSTSAVDSRSQRQKNLCWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQTDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGQPELPLTEREMEILNKTSVSPSTELLPDSTSEEVAPPKPPLPGIRVVDNSPPALPPKKRQSAPSPTRVAVVAPMSRAVSGSSLPVGINRQDFDVECYTQRRLSGGSRSCGGESPRLSPCSSTGKLSRSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQTPPQAACNLSPLPESMGESGPPFVGYSFQLPLGSCLQQDGQQTDTPPALPEKKRRSAVSQTTDSSGCRVSYERHPSQYDNISEDDLQNPAQPVSYPPFAAILPFQQGASSTPVEFVGDFSVPESAGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQSEHIYQQKNKMLMEVYGFSDSFCGSDSTQELAPPPALPPKQRQLEPPSGKDGHPRDLSVSSASGKDSRENGERSPKSLDALESAQSEEEVDELSLIDHNEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQCRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILKLLMELVFRLVCSGELSLARVLRKNILDKVDQKKLLRCAHSDQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSVIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQRQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQVHYEIRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
Protein: Always early (Q2PNP7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRHQLKKPRKMVAAWQNDELFIKRPNFAPRIRISEKPEIQGRVKPGVASKRTENFTKKPSKISVDVSEDEKAKEKEKEQDPYSNDFILGKRLYNFLKYLSSHRWIWCEFVDSFLDKPTLTMGYDMKRFIAEYCPLLHSCFMPRRGWQLVRRNMGKARRFSAAFIELEREELECQRRIVRQLQQHKFNPKENVGYLDQIPKRVPLPLAKDATVSSFLHGNSFEGIVNGTVMGYDPQDYTYLVRFNRNDNAVVLSLPDSQLYSDEETAAVPLSIIMRGNKSSSVISESAKTEKFGNKRYTKELLESVLRVGKLQDVKHKILMDLARMNEDFETFKEIGSSSSRRDAKVTPQRENLQRRYSASMITLHRVNADILEPLRILHDYLVEYQKQDEEEESKRGRPASEVYQKCRMQAEQDLKTAADEKFLKIESDRTQEFVRNLHTILYLNGKLGRENSSNLETIIADLVTHMVDNIQPSLGRKLKDGVDSLEPLRQQVVQIFKDVKKPERFQITQQAPMQTEDGIYNFVVEAQPDTPS
Protein: Secreted frizzled-related protein 5 (Q8AWG4)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt
Sequence:
MRFQWNILAWVNSVLLGLVLWSSAEEYDYYSWQSDNFQNGRFYTKQSQCIDIPSDLHLCHNVGYKKMRLPNLLDHETMPEVKQQASSWVPLLAKRCHRDTQLFLCSLFAPICLERPIYPCRSLCEVVRDSCAPVMESYGFPWPEMLNCNKFPLDNDLCITVQFGSKQVTQPPVTKICTQCEIEQKSETMRVQLCASDFVLRMRIKEVKIENGDRKLIAAQKKKKVLKAGKLKRKEFRKLVLYIKNAASCPCPQLDNLSGSFLIMGRKVDNKLILTAIYKWDKKSKDMKYAVNFMYSYPCSDTISHGTGSHLGSFR
Protein: Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET) (Q9BW19)
Organism: Homo sapiens (Human)
Function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9QWT9}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9QWT9}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9QWT9}. Early endosome {ECO:0000250|UniProtKB:Q9QWT9}. Note=Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis. {ECO:0000250|UniProtKB:Q9QWT9}.
Interaction partners:
- Kinesin-like protein KIF11
- Kinesin-like protein KIF20A
- Kinesin-like protein KIF2C
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Cell division cycle protein 20 homolog
- Disks large-associated protein 5
- Kinesin-like protein KIF23
- Aurora kinase B
- Kinesin-like protein KIF18A
- Kinesin-like protein KIF18B
Sequence:
MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK
Protein: Ras-related protein Rab-32 (EC 3.6.5.2) (Q13637)
Organism: Homo sapiens (Human)
Function: Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:12186851}. Mitochondrion outer membrane {ECO:0000269|PubMed:23084991, ECO:0000305|PubMed:12186851}; Lipid-anchor {ECO:0000305|PubMed:12186851}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:21255211}. Cytoplasmic vesicle, phagosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Melanosome {ECO:0000250|UniProtKB:Q9CZE3}. Melanosome membrane {ECO:0000269|PubMed:23084991}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). {ECO:0000269|PubMed:21255211, ECO:0000269|PubMed:23084991}.
Interaction partners:
- Ankyrin repeat domain-containing protein 27
- Geranylgeranyl transferase type-2 subunit alpha
- Rab proteins geranylgeranyltransferase component A 2
- Ras-related protein Rab-38
- Rab proteins geranylgeranyltransferase component A 1
- cAMP-dependent protein kinase catalytic subunit beta
- BLOC-3 complex member HPS4
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase type II-alpha regulatory subunit
- Ras GTPase-activating protein 1
Sequence:
MAGGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFPNEENDVDKIKLDQETLRAENKSQCC
Protein: Extracellular protease inhibitor 10 (Secreted effector EPI10) (D0NJ41)
Organism: Phytophthora infestans (strain T30-4) (Potato late blight agent)
Function: Secreted effector that interacts with and inhibits the pathogenesis-related P69B subtilisin-like serine protease of host tomato. Inhibition of host proteases by a pathogen extracellular protease inhibitor forms a specific type of defense-counterdefense mechanism between plants and microbial pathogens.
Subcellular location: Secreted {ECO:0000269|PubMed:15980196}. Note=Localizes to host apoplast where it targets defense proteases for inhibition. {ECO:0000269|PubMed:15980196}.
Interaction partners:
- Cystatin-like cysteine protease inhibitor EPIC2B
- Cystatin-like cysteine protease inhibitor EPIC1
Sequence:
MKSAFTLSLALVAVTATISAAADDNCSFGCLDVYKPVCGSNGETYSNSCYLRLASCKSNNGITEAGDGECASTPASSATPSPVTSSTGSTSGTVGCPDMCLDVYDPVSDENGKEYSNQCYMEMAKCKGTGYDDNKRSGNPGISTLDAERKLAFAPGYQGPPCGDMLCPDNYAPVCGSDGETYPNECDLGITSCNHPEQNITMVGEGTLPVTGAATATATATAEVVTRW
Protein: FI05272p (Raw, isoform B) (Q9VLI5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MHKMVKLFLREVLNAWRAKARCNVVPDERTQELFHELSFHPSQKQISEMLQTAKKVARKGGSGQANGLTFGQFCVLAADLKRFRASTISNQPSYCDYQSLSAGLLLPELDDPASSSNQNLQSPAATNSSPAHSSKKPDNHGTELRSTKSFSSVDDTKKKKNATNEPVEVFLGGSCNPTTWRADVAIPALKELGISFYNPQVSDWTPDLIELEHRAKEKARVLFFVMDSETRASAGAIEAAHIAGQNCKQLVLVLHPYKPNQKILNEPISQQEYLDLNRNQLILKELVSRRGLPVLDNIPLGLQRTKDILGGIRDPPSKISSILDTVRGAFDRVNPLNDLLTVEQCKRALLFLGYAQSLVNLDNLNKIIINQRESLKLLQTHSPRAVADDADADGGNCSQPILPSQELIDFDLFCVISAYLSVLQQEIHESGCISPIKGTNVPPPQVYFTNAPDVDIYYSASKNISRTSSNASVPSNSSSGIGHDLERQSLFEQLSRSRDSGTSSPQPTGSSSLGKSPRPQILLNVESIETTEIITTKTIETKPNPVTASTVVHAEEEESDSNDSVLSSNSSIASAGDILCCGGGLDLRDVYLGGSCVLRTKWRQELAVPYLQSKGVSFHTPALHESIQQMILNQEQNQDQSQQPTVPPQEQQQQQRSFVRTRRKCRGNQLQLEEQEELTVAEESLSWSLPPVAVRQSLFNPSLLDSSRVLLFVITNETRSLAPMTLAAHCIGLMYNVVLAVQMLPEDCVLGDEKLTVAAIKDYNRGRSYLIDLAKRQGVPVFSDIRAALECTVAKVKAYNNRDRC
Protein: BHLH transcription factor (Os03g0338400 protein) (cDNA clone:J033029P04, full insert sequence) (Q10LR1)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MMSSRERKKAAALQEKLQILRSITHSHALSNTSILMDASKYIKELKQKVVRLNQEIACAQDALRQNRVTVETLRHGFLVNVFSGKSCPGLLVSILEAFDELGLSVLEATASCTDTFRLEAIGSENLMEKVDEHVVKQAVLRAIRSCSGSGGDHHDDDDDDDDE
Protein: Uncharacterized protein (Q57XK1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Telomerase-associated protein, putative
Sequence:
MLPSAQEVVEVRSPETVKLDLVPDDATAGPEIAGAEHHHSEDSGAAMSHSEGDHREDTNGAMVSDTKSSALDLMEKPEGDGSEEYRKPPAGTDSDTCDAAAEHLFSEEDGEEEGSQQEERDEGSYEDRSEDEEEVEGEPDGEGSDEEQYVMEQEEDYGFVLPPETSKDAVAKVESFVINGKKYTASSFVHNAGFRVLRELKGKKARDLVICASRKPHNILSCKNLHLTNRAVCVKDCYLRLNTLVNNPGKEALLVDPTSAATALFCERTDADHDQSACTALHLMPGIVYVGFPPLRVGYFEGELHKNIALTRLQEGSDTCGTWCAGRRSHIVVTCSFVHYNRGTVYKEAPSPPALPTALFPGMQPREHVGRGRGRNPLGRGRGARGRGGLGRGRGCGAATEGHDRSNNARGRGRGASKELSAGRGRVRPVNVVAAQPPLSSAVVCEEVGGVAPPPEVAITEGGMRAHGVQFLNFVLVLLSVIIAVLVYMLM
Protein: Nuclear receptor co-repressor 2 (A0A8I6A620)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSGSTQPVAQTWRAAEPRYPPHGISYPVQIARPHTDVGLLEYQHHPRDYTSHLSPGSIIQPQRRRPSLLSEFQPGSERSQELHLRPESRTFLPELGKPDIEFTESKRPRLELLPDTLLRPAPLLATGQPSGSEDLTKDRSLAGKLEPVSPPSPPHADPELELTPSRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRVWPAGTNHLEPRVPATVEPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQRFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMDDPMKVYKDRQVTNMWSEQERDTFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQMARSSQEEKEEKEKEKEADKEEEKQDAENEKEELSKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANHEETATPQQSSELASMEMNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKTPAAASEETAFPPAAEDEEMEASGASANEEELAEEAEAYSRLSSCLHVAAVNNSSDTESVPSPRTEATKDAGPKPASTEALPAATQPPVPPPEEPATVPDEPCPAPDASGPPSPVASPPPAAPPAAVDKDEQDQAATVPQTEDAKEQKSEAEELVIDVGKTEEPEAPEEPPESVKSDHKEETEEEPEDKAKGPEAIETVSEAPLKVEEAGSKAAVTKGSSSGATQDSDSSATCSADEVDEPEGGDKGRLLSPRPSLLTPAGDPRASTSPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDTVPPKPAPPVPPPTQHLQPEGDVSQQSGGSPRGKCRSPVPPAEKEAEKASFFPAFPAEGPKLPTEPPRWTSGLPFPIPPREVIKTSPHAADPSAFSYTPPGHPLPLGLHDSARPVLPRPPISNPPPLISSAKHPGVLERQLGTISQQGMSVQLRVPHSEHAKAPMGPLTMGLPLAVDPKKLGTALGSTASGSITKGLPSTRTADGPSYRGSITHGTPADVLYKGTISRIVGEDSPSRLDRAREDTLPKGHVIYEGKKGHVLSYEGGMSVSQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRTITSASIEGLMGRAIPEQHSPHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPPRDLTETYKTRPLDPLGPLKLKPTHEGVVATVKEAGRSIHEIPREELRRTPELPLAPRPLKEGSITQGTPLKYDSGVPSSGSKKHDVRSIIGSPGRPFPALHPLDIMADARALERACYEESLKSRSGTSSGAGGSITRGAPVVVPELGKPRQSPLAYEDHGAPFTSHLPRGSPVTTREPTPRLQEGSLLSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVTGVDLYRGHIPLAFDPTSIPRGIPLEAAAAAYYLPRHLAPSPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAASAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAIDRLAYLPTAPPPFSSRHSSSPLSPGGPTHLAKPTATSSSERERERERERDKSILTSTTTVEHAPIWRPGTEQSSGAGGSSRPASHTHQHSPISPRTQDALQQRPSVLHNTSMKGVVTSVEPGTPTVLRWARSTSTSSPVRPAATFPPATHCPLGGTLEGVYPTLMEPVLLPKETSRVTRPERPRVDAGHAFLTKPPAREPASSPSKSSEPRSLAPPSSSHTAIARTPAKSLAPHHASPDLPAPTSASDLHREKTQSKPFSIQELELRSLGYHSGAGYSPDGVEPISPVSSPSLTHDKGLSKPLEELEKSHLEGELRHKQPGPMKLSGEAAHLPHLRPLPESQPSSSPLLQTAPGIKGHQRVVTLAQHISEVITQDYTRHHPQQLSGPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGTPARGSPHSEGGKRSPEPSKTVLSSSEDAIEPVSPPEGMTEPGHARSTAYPLLYRDGEQGEPRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNIGQPGTEIFNMPAITGAGLMTCRSQAVQEHASTNMGLEAIIRKALMGKYDQWEEPPPLGANAFNPLNASASLPAAAMPITTADGRSDHPLTSPGGGGKAKVSGRPSSRKAKSPAPGLAPGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLAAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
Protein: Photosystem II reaction center PSB28 protein, chloroplastic (Photosystem II protein W-like) (Q8W0Y8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Stromal side {ECO:0000250}.
Interaction partners:
- Oxygen-evolving enhancer protein 1-1, chloroplastic
- Photosystem II repair protein PSB27-H1, chloroplastic
- Oxygen-evolving enhancer protein 3-1, chloroplastic
- Photosystem I reaction center subunit XI, chloroplastic
- Photosystem II CP43 reaction center protein
- Oxygen-evolving enhancer protein 1-2, chloroplastic
- Photosystem I reaction center subunit III, chloroplastic
- Photosystem II 10 kDa polypeptide
- Photosystem II reaction center protein H
- Photosystem II 22 kDa protein, chloroplastic
Sequence:
MACVRSIGSLTSVNHSQRNVPRSGIVLSSCSVLPIKSSSFTGSPVSLPRAQPSSRTALRPMKPVSITMMVKPALQFIQGTDEMTIPDVKLTRSRDGSNGMALFSFDQPSVFDSSGEVGEITGLYMIDEEGVIQSTDVNARFVNGKPEGIVAKHIMRSPKEWDRFMRFMERYSDQNGLQFVKKQ
Protein: Signal transducer and activator of transcription B (Dd-STATb) (STAT5 homolog B) (Q70GP4)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Transcription factor that regulates gene expression during development. Required for optimal cell growth.
Subcellular location: Nucleus {ECO:0000269|PubMed:14701681}. Note=Predominantly nuclear in growing cells and throughout development.
Interaction partners:
Sequence:
MEVTNNGSNNSSTIASTNPPTSPSTTSTSKSLPPLSFLNSQWENKQSNNNNNSNNNNINNNNNNNNNNNNNNNNNNNNNNNSVKMEKLIELPSSSNNSPEFLNGVNNNNNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSGSGGNNSNNNSNISSPPSSSSTSTSVLSSSQSAYMNDKMVAATLDSIGKMESIQRKYEMQIESLMDQIQGYIEKEQKLRSQCQAVEDINAKLENENLQLKKELFEMSRKFKEIDIINLNNTNNNINNNNNNNNNNNNNNNNNSINNNNNNGFSPPPLVKYPSNGSLQQDAKRFKIMEQQSQQQQQMQQQQQIQQQKQYQQQQQQTTSKRKNNISIDGDKEALVAEALGSFVDYAKPSLKRSNSEEVFNSSVYKNKNNINNINNNSNSNNNNGNNSLLNDIQNWQQQQQQQQQLLHQRKKRKDYDYDYNSTQNGKGIPSNSSNNNSSNNNSNNNNNNNSNNNNNIIGSISPPHSSQLQQVSSPQQQQQQQKPNGLKLSISSGSIKDLINSPNKEQSSKSQYPSSLSQSSSIPDMDTDVDSTDEFDFGSNSNNNNNNNNNNNNNNNSNNSNNKKRNNSNNNNLGGDDDDSPDSNDRNGSSSPIDMEPSYDGANLFKTVTPGTITTPQEELLNEIHSLQMQQRETIEKMYIAQKQFLSDRSNGFNNNNEEILRSLQSDQTKLGSTLESELQALNQLYSQTILEPNQLCKLDILLQDVSIQLKQLHLYQMELNYGYGSNEPFPATLVIIKQPFPMVISKFKQLQEDHLCVQLLTGANVEIVSYSPIRAELVFHSKNLTKGSSNLGTQNSLKKNIEKDTQVLDPIKGVAKFPIKFLTGTRKSCVKLHFVLQIKTSDGHIINVPSSTSQPFIVITNDCQWEGSEGTLLKKETFNEKFEISWPHFVNILQKHFLKATKQSPIQPTRPLSMYDFTYLSNTFFGGKPFVSHKDFDSFWSWFGKSIQTLRYKRHISTLWQNGFIFMFLKRDVVTQILKNQDVGTFVILFSEAFPGQLEISYVGTDQKDSLSKSSNDLQSPTTTTTTTTSTRVKHYLVQANDTSGSKRTLPDFLSECNQFTHILQLNIAMIPQTETIPVFKREPKNVVLEPYYSKRQNSQNILGSGYDPLF
Protein: Protein RecA (Recombinase A) (P0DJP0)
Organism: Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
Interaction partners:
- LexA repressor
- DNA polymerase I
- Lmo0418 protein
- Regulatory protein RecX
- Beta sliding clamp
- ATP-dependent DNA helicase
- DNA helicase RecQ
- RecS protein
- Nuclease SbcCD subunit C
- 5'-3' exonuclease
Sequence:
MNDRQAALDQALKQIEKQFGKGSIMKLGEHSDQNISTISSGSLALDIALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQAQGGTAAFIDAEHALDPAYAKNLGVNIDELLLSQPDTGEQALEIAEALVRSGAVDMLVIDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGVINKSKTIAIFINQIREKVGVMFGNPEITPGGRALKFYSTVRLEVRRAEQLKQGTDVMGNKTKIKVVKNKVAPPFRIAEVDIMYGEGISREGELVDMAAEVDVINKSGSWYSYKEERIGQGRENAKQYLKEHTDIRDEISKRVREEYEIDGSSKEPLDEKEETLSLLDDE
Protein: Protein 4.1 (Band 4.1) (Erythrocyte membrane protein band 4.1) (D3ZIP3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTTEKSLAAEAENSQHQKEEGEGATNSGQQESQLEEASQAAAAEGSNQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQVSEEEGREVESEREKGEGEQKETELGTSLDEDVILKAPIAAPEPELKTDPSLDLHSLSSIETQPAQEEHREDPDSETKEGEGIEECSGTEVKEDPESRAEREPETSQKPIRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAVWDSTTSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTVQSELGDYDPELHGVDYVSDFKLAPNQTRELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTLPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAAESTDRSPRPTSAPAIAQSQVMEGPGAPAKKAPKEAVKVEEKRGEEPAEPEPEPTEAWKVEKPHTEVTVPTSNGDQAQKLAEKGEDLIRMRKKKRERLDGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQVPTGDGPPLVKTQTVTISDTANAVKSEIPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLTAQTITSETTSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE
Protein: Uncharacterized protein C144.01 (Q9UTM1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MSKLKAQSALQKLIESQKNPNANEDGYFRRKRLAKKERPFEPKKLVQQQQRLKEKKKNENIIYLKKTMRVTPSEEKIHEMINQKRETKKRKRKQKKKNDDDYGVFEEDMLEL
Protein: RuvB-like 1 (EC 3.6.4.12) (Pontin) (O17607)
Organism: Caenorhabditis elegans
Function: Possesses single-stranded DNA-stimulated ATPase and ATP dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). May participate in several chromatin remodeling complexes that mediate the ATP-dependent exchange of histones and remodel chromatin by shifting nucleosomes (By similarity). Involvement in these complexes is likely required for transcriptional activation of selected genes and DNA repair in response to DNA damage (By similarity). Involved in the Ce-Tor signaling pathway whereby it is required for the accumulation and localization of box C/D snoRNP to nucleoli to regulate ribosomal maturation and thus protein synthesis. Antagonizes the transcriptional activity of transcription factor pha-4, to control postembryonic development and adult longevity. Has a role in pharyngeal development. Has a role in gonadal development.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25437307}. Nucleus {ECO:0000269|PubMed:25437307}.
Interaction partners:
- RuvB-like 2
- Helicase ssl-1
- Actin-like protein C08B11.6
- Transcription-associated protein 1
- Non-specific serine/threonine protein kinase
- HIT-type domain-containing protein
- Actin-related protein 4
- DNA methyltransferase 1-associated protein 1
- Nop domain-containing protein
- Histone H2A.V
Sequence:
MDMEVDEAISGTSSSRLAPIEEVKPTPKQIKRIAAHSHVKGLGIDTETQEAHYEAAGFVGQAPARTAASIVVDMIRLKCMAGRAVLIAGPPATGKTAIALAMSQELGDGVPFVPLVASEVFSNEVKKTEVLMRSFRRAIGLRVKETKDVYEGEVTELSPVEASDNSGMGKTISHLVLSLKTAKGSKQLKLDPSIYDSILKQRVEVGDVIYIEANSGIVKRVGRCDVYASEFDLEADEFVPMPKGDVRKSKDIVQNVSLHDLDIANARPQGRQGDVSNIVSQLMTPKKTEVTDRLRSEINKVVNEYIESGVAELMPGVLFIDEVHMLDVECFTYLYRALESPMAPVVVFATNRGTTTVRGLGDKAPHGIPPEMLDRLMIIPTMKYNEEDIRKILVHRTEAENVQFEEKAFDLLSKVGAEKSLRYALQLIAPARLCAQTCGREVIEVEDVDRCTKLFMDRGESLKKAEEEMRQPKNKK
Protein: tRNA-cytidine(32) 2-sulfurtransferase (EC 2.8.1.-) (Two-thiocytidine biosynthesis protein A) (tRNA 2-thiocytidine biosynthesis protein TtcA) (P76055)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01850, ECO:0000305}.
Interaction partners:
- tRNA sulfurtransferase
- tRNA-2-methylthio-N
- tRNA-specific 2-thiouridylase MnmA
- Sulfur carrier protein TusA
- Uncharacterized protein YdaQ
- Cysteine desulfurase IscS
- Sulfurtransferase TusE
- tRNA-dihydrouridine
- tRNA
Sequence:
MQENQQITKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPACWQPEEDENQLDELRLNVVEVK
Protein: ADAM metallopeptidase domain 22 (A0A8I6AMW2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MQAVAAAFFWLLCVLGTYPLARCGRAGDASLRELERGDGNRFLERQSTVPLRLIYRLGGEDETQHEQLNTRVRGDPGGRQPTHVDKASFRVDAFGTSFILDVLLNHELLSSGYVERHIEHGGKVVENKGGEHCYYQGQIRGNPASFVALSTCHGLHGMFYDGNHTYLIEPEENEMSQESQFHSVYKSRLLEFPLDDLPSEFQRINITAPQFTLKPRLKRRKRQLLRFPRNVEEETKYIELMIVNDHLMFKKHRLSVVYTNTYAKSVVNMADVIYKDQLKTRIVLVAMETWAADNKFAISENPLVTLREFMKYRRDFIKEKADAVHLFSGSQFESSRSGAAYIGGICSLLRGGGVNEFGKTDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDTGYYLPKKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECALEGAECCKKCTLTQDSQCSDGLCCKKCKFQPLGTVCREAVNDCDIREICSGNSSQCAPNVHKMDGYSCDGTQGICFGGRCKTRDRQCKYIWGQKVTASDRYCYEKLNIEGTEKGNCGKDKDTWTQCNKRDVLCGFLLCTNIGNIPRLGELDGEITSTLVVQQGRTLNCSGGHVKLEEDVDLGYVEDGTPCGPQMMCLEHRCLPMASFNFSTCLSNKAGTVCSGNGVCSNELKCVCNRHWTGADCGTHFPHNDDAKTGITLSGNGVAGTNIIIGIIAGTILVLALILGITAWGYKNYREQRQLPQGDYVKKPGDGDSFYSDFPPGGSADSASSSKKRSAFLSHFQISTCSITHYSISQNISLFCSRSNGLSHSWSERIPDTKHISDICENGRPRSNSWQGNVGGNKKKIRGKRFRPRSNSTETLSPAKSPSSSTGSIASSRKYPYPMPPLPDEEKTVNRQSARLWETSI
Protein: Major facilitator superfamily (MFS) profile domain-containing protein (Q23514)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Receptor-type guanylate cyclase gcy-9
Sequence:
MYRILSQNENECSKNDEDVNIRRAIDDEALESKRWKRRHVVAILALLGFANIYAMRANLSIAIVEMTSGTERKVNGTTLHVLGDFENWTPMTQGVVLSSFFYGYIVSQLPGGYLAYTHGAKTIFFAGTFGTAVFTLLTPPFARMGYGMLVFARFMEGLLEGVTYPAMHVIWSRWAPPMEQTKLATFAFSGSYFGTVVAMPLSAYLGEHFGWPMIFWFFGALGVIWCMVWYKTVHDRPEDDPKISTSELALLQRDAVSQNHYIVPWAQILRSKPVWAVIVAHSAQNLGFYIMLTNLPKMLKDIAGYNVEKAGIASSLPYFLMGFQIITGGQLCDYLRRDKHYDTLFVRKMACALGFIGQSVFLFLVMTTSNSLLLVLFFSISIGLGGICWCGFSVNHLDLAPQYAGHLMATSNTFATIPGIFGPLLVGAIVQNGTIGEWNVIMYIIISAYLLGAAIFWKFADATLQPWAAEHTSFVGQLE
Protein: Tropomyosin (Major allergen Pen m 1) (Tropomyosin, fast isoform) (Tm-Penm-fast) (allergen Pen m 1.0101) (A1KYZ2)
Organism: Penaeus monodon (Giant tiger prawn)
Function: Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
Interaction partners:
Sequence:
MDAIKKKMQAMKLEKDNAMDRADTLEQQNKEANNRAEKSEEEVHNLQKRMQQLENDLDQVQESLLKANIQLVEKDKALSNAEGEVAALNRRIQLLEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKANQREEAYKEQIKTLTNKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEKEKYKSITDELDQTFSELSGY