wanglab/gogpt-training-data huggingface dataset:
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q96II5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQPSRFYHSVQDLSGGSRQHEAPSNRPLNELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
Protein: Lymphocyte antigen 86 (Ly-86) (Protein MD-1) (O88188)
Organism: Mus musculus (Mouse)
Function: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.
Subcellular location: Secreted, extracellular space. Note=Associated with CD180 at the cell surface.
Interaction partners:
- CD180 antigen
- Lymphocyte antigen 96
- Cathepsin S
- TYRO protein tyrosine kinase-binding protein
- 5'-3' exonuclease PLD4
- Complement C1q subcomponent subunit A
- Complement C1q subcomponent subunit B
- Macrophage colony-stimulating factor 1 receptor
- Toll-like receptor 4
- Allograft inflammatory factor 1
Sequence:
MNGVAAALLVWILTSPSSSDHGSENGWPKHTACNSGGLEVVYQSCDPLQDFGLSIDQCSKQIQSNLNIRFGIILRQDIRKLFLDITLMAKGSSILNYSYPLCEEDQPKFSFCGRRKGEQIYYAGPVNNPGLDVPQGEYQLLLELYNENRATVACANATVTSS
Protein: Lectin-like protein At1g53080 (Q9LNN3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted, extracellular space, apoplast {ECO:0000250}.
Interaction partners:
Sequence:
MQIHKLCIFVLFISLLSSKTISAVKFNFNRFDGTNLIFIGYAELGPATDGMSRSGALSMTRDNIPFSHGQGLYTDPIPFKSSNNTSSSVYSFKTSFTFSITPRRSNPNPGHGIAFIVVPTVAYEYDQDSTRGFLGLVNLTTNGNPNNHLFAVEFDVFQDKRFGDINDNHVGVNINSVNSKVSEKAGYWIQTRTRGKNQWLFKEVKLSSGDNYKAWIEYKNSKVIVWLAPAHLKKPKRPLIETQVDLSEVVLETMYTGFSGSMGRGVERHDIWSWSFENTAKNN
Protein: Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8) (O15397)
Organism: Homo sapiens (Human)
Function: Involved in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, may serve as receptor for nuclear localization signals (NLS) and promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of the signal recognition particle protein SRP19. May also be involved in cytoplasm-to-nucleus shuttling of a broad spectrum of other cargos, including Argonaute-microRNAs complexes, the JUN protein, RELA/NF-kappa-B p65 subunit, the translation initiation factor EIF4E and a set of receptor-activated mothers against decapentaplegic homolog (SMAD) transcription factors that play a critical role downstream of the large family of transforming growth factor beta and bone morphogenetic protein (BMP) cytokines (Probable).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Protein argonaute-2
- Ubiquitin-like protein FUBI
- Importin subunit beta-1
- Protein argonaute-1
- Importin-9
- Transportin-1
- Ran-specific GTPase-activating protein
- GTP-binding nuclear protein Ran
- RB-associated KRAB zinc finger protein
- Exportin-1
Sequence:
MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN
Protein: Probable phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM) (dPGM) (Q54NE6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Interaction partners:
- Phosphoglycerate kinase
- Enolase A
- Enolase B
- Triosephosphate isomerase
- Glucose-6-phosphate isomerase
- Pyruvate kinase
- D-3-phosphoglycerate dehydrogenase
- Fructose-bisphosphate aldolase
- Multiple inositol polyphosphate phosphatase 1
- Transketolase
Sequence:
MVYKLVLIRHGESTWNKENKFTGWTDVDLSEKGVQEAHEAGKRLLKAGFTFDIAYTSVLKRAIRTLWILLEELNLYWIPVSRQWRLNERMYGSLQGLNKSETAAKYGEDQVLIWRRSYDIPPPALEESDERYPGNDPRYAKLDKSDLPKTECLKDTVERFLPLWNDTIAPTIKSGQKVLIAAHGNSIRALVKYLDNIADDKIVSMDIPTGIPLVYELDENLKPIKHYYLADESELNAAIQAVANQGKAK
Protein: CD59A glycoprotein (MAC-inhibitory protein) (MAC-IP) (Membrane attack complex inhibition factor) (MACIF) (Protectin) (CD antigen CD59) (O55186)
Organism: Mus musculus (Mouse)
Function: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
- Complement decay-accelerating factor, GPI-anchored
- Complement decay-accelerating factor transmembrane isoform
- Membrane cofactor protein
- CD59B glycoprotein
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit A
- Vitronectin
- Complement factor H
- C4b-binding protein
- Plasma protease C1 inhibitor
- Complement receptor type 2
Sequence:
MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL
Protein: HTH-type transcriptional regulator GadW (P63201)
Organism: Escherichia coli (strain K12)
Function: Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC. Repression occurs directly or via the repression of the expression of gadX. Activation occurs directly by the binding of GadW to the gadA and gadBC promoters.
Interaction partners:
- HTH-type transcriptional regulator GadX
- Transcriptional regulator GadE
- Glutamate decarboxylase alpha
- Outer membrane protein Slp
- Glutamate decarboxylase beta
- Acid stress chaperone HdeA
- Glutamate/gamma-aminobutyrate antiporter
- Protein HdeD
- HTH-type transcriptional regulator DctR
- DNA-binding transcriptional activator EvgA
Sequence:
MTHVCSVILIRRSFDIYHEQQKISLHNESILLLEKNLADDFAFCSPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESGVNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAERMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYFINTFRQYYGVTPHQFAQHSPGTFS
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q8T3S1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDDFGSTASDLEEATCPMQANATFSIDWRVTLLDHWLDLYLGYMNRLHMLLSLAGRLHLLSRHILGTLGQDPIFMGVLQGSLLMLFLFLMHLLRLWSCGYAVERPLNPTPDVAKELSCDFNFVSEQEKRAAQEAATEALLEVEEKKRRKRFTKKRNCVSAGPILIALRHQSKRPKHHRHAALPFEPVTPGEIILDTYLPPRELPLTIRLPQLAEPVKEEEVEYIELKSEPRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQYCRGGYHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAIRDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSYISSIEKQTKSRAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLDKEDTTTTTSSTLNSNTTSSLASKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKNQSQSSQNNTYTIQSLIDNSNVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDYLFDPHAGESYSRDEDHLAHIVELLGSIPQSVIFRGKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDPVEAKKFSDFLLPMLEYNPVIRASAAECLQHPWLEQEEFV
Protein: Protein MANNAN SYNTHESIS-RELATED 1 (AtMSR1) (EC 2.4.1.-) (O-fucosyltransferase 25) (O-FucT-25) (O-fucosyltransferase family protein) (Q9LU40)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Glycosyltransferase involved in mannan biosynthesis.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:22966747}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- O-fucosyltransferase 23
- Peptidyl-prolyl cis-trans isomerase CYP21-1
- AT4g38690/F20M13_250
- Probable magnesium transporter NIPA7
- Probable magnesium transporter NIPA6
- At3g26950
- At4g12700
- AT3g56750/T8M16_80
- At1g61240
- Probable methyltransferase PMT4
Sequence:
MGVDLRQVVAGILTITMFVMLGQMLHRDYFDSLQEKAQGDAQDIEFEGSKVSVKDGLVGTVEGSKGLWMEDNTDLTPCWPTLLSDDAVSSKGYVTFSLTNGPEYHISQITDAVMVAKHLGATLVLPDIRGSKPGDERNFEDIYDADKLIKSLENVVKVVKKLPEEVSLRNMAIVKVPTRVTEDYIKEHIDPIFKSKGNIRVASYFPSVNLRKSSQDGETDPVACLAMFGSLELQPEVNAVAESMVERLRTHSRKSGGRFIAVDLRIDILEKKNCHTTGVVGSKTCYNAQEIALFLRKLGFASDTTIYLTQPRWDSSLNILKDIFPKTFTKEAIMPASKRSKYLESVSSEYENVIDFYISSRSDVFVPAISGLFYANTVGKRIALGKPQVLVPAEISETSGLATDFISPYISKKNHLAYSCFC
Protein: Annexin A2 (Annexin-2) (Q6TEQ7)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane. Note=In the lamina beneath the plasma membrane. {ECO:0000250}.
Interaction partners:
- Protein S100-A10
- PDZ domain-containing protein.
- Uncharacterized protein.
- Protein S100
- Protein S100-A4
- Annexin.
- Plasminogen
- S_100 domain-containing protein
- S_100 domain-containing protein
- Uncharacterized protein.
Sequence:
MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
Protein: Scribble planar cell polarity protein (D3ZWS0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Lethal
- LLGL scribble cell polarity complex component 2
- Ubiquitin-protein ligase E3A
- Cell division control protein 42 homolog
- Disks large homolog 4
- Catenin beta-1
- Rho guanine nucleotide exchange factor 7
- Disks large homolog 1
- RAC-alpha serine/threonine-protein kinase
- Vang-like protein 2
Sequence:
MLKCIPLWRCNRHVESVDKRHCSLQVVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPVELGGLALLTDLLLSQNLLQRLPEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPRSLGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHLNLKALWLAENQAQPMLRFQTEDDAQTGEKVLTCYLLPQQPLPSLEDPGQQSSPSESCSDAPLSRVSVIQFEDPLEGEEDAEEAAAEKRGLQRRATPHPSELKVMKRGIEERRNEAFVCKPDPSPPSPSEEERRLSAESALSGNSVPSASTASDGEPETLPAEVQGLGQQEAMPGQEEYPEEDYNEPTVHFAEDTLIPREDGEGEEGQPEAPWPLPSGRQRLIRKDTPHYKKHFKISKLPQPEAVVALLQGVQTDREGPTAGWHNGPHTPWAPRAHEEEEEEENRDEEEGEASMEEDDKEEAVASAPSVKGVSFDQANNLLIEPARIEEEELTLTIVRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAAHAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRERMVEPENAVTITPLRPEDDYSPREWRGGGLRLPLLQPETPVPLRQRHAACLVRSEKGLGFSIAGGKGSTPYRAGDAGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSLLTAASTTISLLLERETGGAYPPSPPPHSSSTPTATVAATMTTAIPGEPLLPRLSPSLLATALEGPYPVEEICLPRAGGPLGLSIVGGSDHSSHPFGVQDPGVFISKVLPRGLAARCGLRVGDRILAVNGQDVREATHQEAVSALLRPCLELCLLVRRDPPPPGMRELCIQKAPGEKLGISIRGGAKGHAGNPCDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHAEAVQLLRSVGDTLTVLVCDGFDTSTTTALEVSPGVIANPFAAGLGHRNSLESISSIDRELSPEGPGKEKELASQTLPWEPESAETTGRNQEPLKLDYRVLAAVPSAGSLQRGPCATTGGKMTEAPSSPGSQQTKPGVIQPLAQAWPRDSPAPRGRDGPCSPPSPDELPANVKQAYRAFAAVPTVHPPENSATQPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQQKRAQMLREEAVTSGPDTGLASDRESLDDEQEAEQPWAGPSHAGGLSPSSPTPLGGSAPVRTAKAERRHQERLRMQSPELPAPERALSPAERRALEAEKRALWRAARMKSLEQDALRAQMVLSKSQEGRGKRGPLERLAEAPSPAPTPSPTPLEDFGLQTSTSPGRLSPDFVEELRTLDPSPSPGPQEEDGEVALVLLGRPSPGTVGPEDMTLCSSRRAMRPGRRGLGPVPS
Protein: Treble clef zinc finger domain-containing protein (Q582I9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Peptidyl-prolyl cis-trans isomerase
- Uncharacterized protein
- Uncharacterized protein
- 50S ribosomal protein L13, putative
- Large ribosomal subunit protein uL4m
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Tetratricopeptide repeat
Sequence:
MYVKLQTRCIPSLFLPCHINFDCVVCGGEGEQAQGKKDTDAHILVVCVLQQYSVVTNSRRGNRSSCSRIMLRSFRSNAFGLLIPGACTIRGRHLPVSSLEGTVGFTRLTSARALFSATHLLWRRQHGPTNVLFQLDALPPNLQREFHKDENAVNLTYLVDLPSSKIASSHEDSSDGTTKSDTKSPVIKVLPTWAHIVTWCCATCGCQWSARPVDRTDPQVAAFYSCPRCAARTAKKHCSDTPLAVSPSTPSFPPGRRFAEAFPLLAAQWDACRNSVIHNKVLFESVADVPLPCATIVWWSCPHCGEPWRESVNSRVQRLVQQQQKHSSNGNVKSNNTCIPLCPSCEDRGLSLTVPKDGNEGSKEKSSSERRSKKKGNQNSELKRFLKDSPLLLAEAQLQPHEDPGTIALRSNKLVCWKCRRCTYEFVASVADRFLRYKRCPQCTGEKRTPLNLLSIQRPDVLREIARTVVRGKLLKMTVHDDTVVPFVCRSCLSIYRMPIRLRCLLPEGATACSKCMWSRSKFTREVVSVGKGQKGAPFRSPPKKKRGRDSYAVVDNELHLRDTDLMN
Protein: Neurotoxin BmK-M10 (Alpha-neurotoxin TX9) (BmK AngM1) (BmK-X) (BmKX) (BmK10) (BmKalphaTx9) (Bmk M10) (BmkM10) (Neurotoxin M10) (O61705)
Organism: Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)
Function: Binds to voltage-dependent sodium channels (Nav) and voltage-dependent delayed rectifier potassium channels and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. Administration to mice at a dosage of 0.8 mg/kg produces an analgesic effect.
Subcellular location: Secreted {ECO:0000269|PubMed:15200476}.
Interaction partners:
Sequence:
MNYLVMISFALLLMKGVESVRDAYIAKPENCVYECGITQDCNKLCTENGAESGYCQWGGKYGNACWCIKLPDSVPIRVPGKCQR
Protein: Leucine-rich repeat transmembrane neuronal protein 1 (D4A6D8)
Organism: Rattus norvegicus (Rat)
Function: Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19285470}; Single-pass type I membrane protein {ECO:0000269|PubMed:19285470}. Postsynaptic cell membrane {ECO:0000269|PubMed:19285470}; Single-pass type I membrane protein {ECO:0000269|PubMed:19285470}.
Interaction partners:
- Neurexin-3
- Neurexin-2
- Neurexin-1
- Calsyntenin-3
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L1
- Neuroligin-1
- Adhesion G protein-coupled receptor L2
Sequence:
MDFLLLGLCLHWLLRRPSGVVLCLLGACFQMLPAAPSGCPGQCRCEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITELANTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLIKVNFAHFPRLISLNSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPYLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLSNFQGRYDANLQCASPEYAQGEDVLDAVYAFHLCEDGAEPTSGHLLSAAVTNRSDLAPPESSATTLVDGGEGLHDSTLEPITVAIPGGEHAENAVQIHKVVTGTMALIFSFLIVVLVLYVSWKCFPASLRQLRQCFVTQRRKQKQKQTMHQMAAMSAQEYYVDYKPNHIEGALVIINEYGSCTCHQQPARECEV
Protein: Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase) (F0QRW4)
Organism: Mycoplasma suis (strain Illinois)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00318}. Secreted {ECO:0000256|HAMAP-Rule:MF_00318}. Cell surface {ECO:0000256|HAMAP-Rule:MF_00318}. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. {ECO:0000256|HAMAP-Rule:MF_00318}.
Interaction partners:
- Pyruvate kinase
- phosphoglycerate mutase
- Glucose-6-phosphate isomerase
- Fructose-1,6-bisphosphate aldolase, class II
- Phosphoglycerate kinase
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Large ribosomal subunit protein uL4
- 6-phosphofructokinase
- Multifunctional fusion protein
Sequence:
MAFSIENLFAYELIDSRGNPTVACIAKVAKGKFLSKKSFTAKVLVPSGASTGAKEALELRDGDSSRFGGKGVKKAVHYINYVLGPSLIENDVNPADQAELDRFLMDLDGTENKSRYGANTILAVSLSVAKAVAKAKGLPFYQYVAELSGNPKVRKYVLPLPMVNVINGGAHSDNSLDFQEFMFVPVGASSMHEAVRISAECFHALAKYLKSKGLSTAKGDEGGFAPNFNSNEEALNAMLIAIANAGYKAGVIHGHVAIALDCAASELYDSNTKLYKFKKMIKAGCLSEEAGTKGTVQMIDYYVDLVEKYPIISIEDPLAEDDYEGFALLQKRIGKKVQIVGDDLYCTNPELTQMGIEKGLSNSVLIKVNQIGTLSETLNTMSLAKKAGWSCIISHRSGETEDTTIADIAVGTAAGQIKTGSFSRSERIAKYNRLLEIEIDLTSVNSTFYGLYSLFSLDFNNTELFKAKSYMVNERTGEVKCEVLKAELDQSFNKPSQIFDGVSAGVNPSEESEIKSMEAQKIEDDQEGEDKKKKTRFSKS
Protein: Adenylate isopentenyltransferase (HlAIPT) (EC 2.5.1.112) (EC 2.5.1.27) (Adenylate dimethylallyltransferase) (Cytokinin synthase) (Q5GHF7)
Organism: Humulus lupulus (European hop)
Function: Involved in cytokinin biosynthesis. Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP, ADP and AMP. GMP, IMP, CMP or UMP are not used as substrates.
Interaction partners:
Sequence:
MDYASVAMAAAPTTTTTTNVSLRRQRHRKEKLLVLMGATGTGKSRLSIDLAAHFPLEVINSDKMQVYKGLDITTNKISVPDRGGVPHHLLGEVDPARGELTPADFRSLAGKAVSEITGRRKLPVLVGGSNSFIHALLVDRFDSSGPGVFEEGSHSVVSSELRYDCCFLWVDVSVKVLTDYLAKRVDDMLELGMFDELAEFYSPEDEDHDEDSATRTGLRKAIGVPEFDRYFEKFRPGDVEGEDPGRDRVRRGAFEEAVRAIKENTCHLAKRQIGKILRLKGAGWDLRRLDATESFRAAMTSDSGEKCTEIWEKQVLEPSVKIVSRFLDE
Protein: Irditoxin subunit A (IrTxA) (A0S864)
Organism: Boiga irregularis (Brown tree snake)
Function: This bird and reptile-specific postsynaptic neurotoxin inhibits the chick muscle alpha-1-beta-1-gamma-delta (CHRNA1-CHRNB1-CHRNG-CHNRD) nicotinic acetylcholine receptor (nAChR) 100-fold more compared with the mouse receptor. In vivo, produces rapid flaccid paralysis, dyspnea and increased respiratory rate in geckos. At sublethal doses geckos were immobilized for up to three days and then recovered. Chicks injected with lethal doses showed rapid onset of inactivity, dyspnea and neck droop, and no extended paralysis with survival was seen.
Subcellular location: Secreted {ECO:0000269|PubMed:18952712}.
Interaction partners:
Sequence:
MKTLLLAVAVVAFVCLGSADQLGLGRQQIDWGQGQAVGPPYTLCFECNRMTSSDCSTALRCYRGSCYTLYRPDENCELKWAVKGCAETCPTAGPNERVKCCRSPRCNDD
Protein: Meiotic plaque component protein 54 (Q08550)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation.
Subcellular location: Prospore membrane. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the ends of spindle microtubules in cells in meiosis. Localizes to all four spindle pole bodies during meiosis, ADY1 is required for this localization.
Interaction partners:
- Sporulation-specific protein 21
- Sporulation-specific protein 74
- Accumulates dyads protein 4
- Accumulates dyads protein 3
- Chaotic nuclear migration protein 67
- Prospore formation at selected spindle poles protein 1
Sequence:
MPEDTSYSNSFEDYYNNSHAISPYKDSFYKEMTPSKPNVRFGDDDVNIFDQRKKVNEINKNNTVKRSIPSSISTTITPNKSSLKSPRGKRASKNSFDNETKLESKNETLKEVNDAVNRCYALCNIPTKHVSINSISDLAQTFETLAVGITHETNRKAECERSKNAIDSLYYHEQLEKKELNEKSLQMAIDHLLKVTKQNLRQADDGNKLKETEALKSFIEEIEEVDDNKISINSLQQQLLEEKTANNILRRDYYKLQERGRRLCHEFQELQDDYSKQMKQKEYEVQKLKNEIKVLLNMNDNLKAEKAHYSQKEKQYFQKYTYIEKYMNHVKEEYNRKEDECKKLNFIIDKSMKKIEHLERSLQTQFTAQNSFSTAMIQEEGPKDAHLKDRYHKVKEFMEQKLQTSKINDPSCSEAEALDNVLCLIESSMKTLDKNSKCYPIATKKCIKYVTDSPRLKENEHVTN
Protein: CCZ1/INTU/HSP4 first Longin domain-containing protein (A0A1D8PQ69)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Vacuolar fusion protein MON1
- Probable vacuolar protein sorting-associated protein 16 homolog
- Tethering complex ATP-binding subunit
- E3 ubiquitin-protein ligase PEP5
- Vacuolar protein sorting-associated protein 41
- CNH domain-containing protein
- Ypt7p
- CORVET complex membrane-binding subunit
- Ras-related protein SEC4
- Rab family GTPase
Sequence:
MNNYFTKYIPNIRLSNTGDSDDHTIGNSTNSLPHINYIIIFNPTFVSPKAESDEELIKQIIVFLQGKDLPESQFSQIEQLKLIGLLRGIESLGESFSNSTTSTTTGKKPTILKSLDSSTVMIELESNYFLACNITISSQINDQTVNGINQQLLKSIMQSQRYFELFNKSIDYTYNQYGINYLQDSLKSFWQNFLTMYNSQSIKIPISPTSLINWFNGLNYQGFLGLLPYTQYKKSSIIINQQIREDIELFMNDNKSVSGVLINYFNLKLPKRHGVVYMNTIGNKYIDNDGLIDIYNWLEYNQYHDNLSNLNNGGVLSSNLSVASSPPQEGENQDGNTSDGTADTQFGFDVSSGLRVLNPVNLTNNLVISPINYTVSTVMEGTQVSNWLAMPQFIKKLTVGDDNETAELPPDQTADINENRSEEDEDDLSGEFIIGLQSDGSISRQVIYLKTTDSIYQEHQLVTYHKDDIYVTLVCESSDPKLDSSGFYKSLETSLLNPIIEQIETVAMGGSMLQTSVNSIRSLYVPNDIDQDFFYITCNPKQRNFQSSLPYLPHLSNMNSDTLTKYQLTALYYLHDQLSNIFQPTFFENQLHEFFHKFTSNKLNDWMFYYIKYQDKYIIIMKNKSKNTTSVLTNNQLSASVPPTIERSIVNRISEGVLDYTKLGFLENLGDDVKYWLGTQQEDLESIEQVSLS
Protein: Telomere-binding protein subunit beta (TEBP beta) (Telomere-binding protein 41 kDa subunit) (P16458)
Organism: Sterkiella nova (Ciliate) (Oxytricha nova)
Function: May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
Subcellular location: Nucleus. Chromosome, telomere.
Interaction partners:
Sequence:
MSKGASAPQQQSAFKQLYTELFNNEGDFSKVSSNLKKPLKCYVKESYPHFLVTDGYFFVAPYFTKEAVNEFHAKFPNVNIVDLTDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTRYPVNLFRDDEFKTTIQHFRHTALQAAINKTVKGDNLVDISKVADAAGKKGKVDAGIVKASASKGDEFSDFSFKEGNTATLKIADIFVQEKGKDALNKAADHTDGAKVKGGAKGKGKAAAKAAKGKKLSAKKGDSSAADVRKSVDKIVKYTPSKGSRKDTPQKSQAPAAGKSSAKKGGKKAVPSAPSPSGKKSALTTDKMTMAQFVKYLDWHEKKKGGKVSSGGKVLGKRSAGKASATSGKASKASKKTAAKK
Protein: Ammonium transporter 2 member 3 (Ammonium transporter 2;3) (MtAMT2;3) (G7LAA8)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Involved in ammonium transport (By similarity). Required for arbuscular mycorrhizal (AM) symbiosis with AM fungi (e.g. Glomus versiforme and G.intraradices) in low nitrogen conditions.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25841038}; Multi-pass membrane protein {ECO:0000255}. Note=Present on the periarbuscular membrane in cells containing arbuscules during arbuscular mycorrhizal (AM) symbiosis with AM fungi (e.g. Glomus versiforme). {ECO:0000269|PubMed:25841038}.
Interaction partners:
- Nitrogen regulatory protein P-II
Sequence:
MNFNSSKYISHLPESLLPNDASPEWNNKADNAWQLTAATLVGLQTVPGLVILYGSMVKKKWAVNSAFMALYAFAAVLVCWVLWAHHMAFGTKLLPFVGKPNFALSQKFLLSKASTNYYLPMADFVFYQFAFAAITLVLLGGSLLGRMNFYAWMLFVPLWLTLSYTVGAFTIWGNGFLEGKIIDYAGGFVIHLSSGVAGFTAAYWVGPRTSNDRQNFPPNNIIHMLGGAGFLWMGWTGFNGGAPFQVGEITSLAIFNTHLCTATSILVWISLDMAVYKKGSLIGSVQGMMTGLVCITPGAGLVDPWAAILMGALSGSIPWYTMMVLHKKSPFFQSVDDTLGVFHTHAVAGILGGILSGVFAKPKLLRILYGPYGSGLLYSYFDDNIGQGIKQMWYQLLGAVFITIWNVVITSLICILLNRFVNLRMQEEDLEVGDDAAHGEEAYVLWGDGERMRLPLRRDISPIIPYISHQRHSFPINKIDE