wanglab/gogpt-training-data huggingface dataset:
Protein: Inner membrane protein YeeA (P33011)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- DNA gyrase inhibitor
- Pole-localizer protein TmaR
- Protein AmpE
- Uncharacterized protein YghW
- Uncharacterized protein YhfK
Sequence:
MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPESTWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCAAAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTGIWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIAPASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQQILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLNNHHDLKVVETPIYGYVWLNMETAHQLELLSNLICRALRK
Protein: N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)] (O08760)
Organism: Mus musculus (Mouse)
Function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
Subcellular location: Nucleus, nucleoplasm {ECO:0000250}. Nucleus speckle {ECO:0000250}. Nucleus matrix {ECO:0000250}. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. {ECO:0000250}.
Interaction partners:
- DNA repair protein XRCC1
- Adenine DNA glycosylase
- Endonuclease 8-like 1 lyase Neil1)
- Endonuclease III-like protein 1 lyase)
- Endonuclease 8-like 2 lyase Neil2)
- DNA repair nuclease/redox regulator APEX1
- Endonuclease 8-like 3
- DNA polymerase beta
- DNA ligase 1
- DNA mismatch repair protein Msh3
Sequence:
MLFRSWLPSSMRHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTEDQLYCTVYRGDDSQVSRPTLEELETLHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNLHALAGPEAETHLRKLGLGYRARYVRASAKAILEEQGGPAWLQQLRVAPYEEAHKALCTLPGVGAKVADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLANKELGNFFRNLWGPYAGWAQAVLFSADLRQPSLSREPPAKRKKGSKRPEG
Protein: Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1) (Q9UM11)
Organism: Homo sapiens (Human)
Function: Substrate-specific adapter for the anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin-protein ligase complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis. Acts as an adapter for APC/C to target the DNA-end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation. Through the regulation of RBBP8/CtIP protein turnover, may play a role in DNA damage response, favoring DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR).
Subcellular location: [Isoform 2]: Nucleus {ECO:0000269|PubMed:34788397}.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm.
Interaction partners:
- Anaphase-promoting complex subunit 7
- Cell division cycle protein 27 homolog
- Anaphase-promoting complex subunit 5
- Anaphase-promoting complex subunit 4
- Cell division cycle protein 16 homolog
- Serine/threonine-protein kinase PLK1
- Cell division cycle protein 23 homolog
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 1
- G2/mitotic-specific cyclin-B1
Sequence:
MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
Protein: Hemese, isoform B (Hemese, isoform C) (Hemocyte-specific protein HEMESE) (MIP14282p) (Q8I0K8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Hemolectin, isoform A
Sequence:
MHNFQLTVVFLALFTFTSSFGYRSEHPHRKPIHSNRPSPTTTMTTDSTSTSFMTTDSTPSETESTSDTSTEESTQISDFTESSTESSTTAKIFLKDNEISKPENSNTLLISVYGIVITLAILVALIYCIRRHYGSYSVKEQCKPIESTAYFNNIKY
Protein: Calmodulin regulator protein PCP4 (Brain-specific antigen PCP-4) (Brain-specific polypeptide PEP-19) (Purkinje cell protein 4) (P63054)
Organism: Mus musculus (Mouse)
Function: Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls. For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways.
Interaction partners:
- Calmodulin-like protein 4
- Calmodulin 5
- Calmodulin-4
- Calmodulin-like protein 3
- Calmodulin-1
Sequence:
MSERQSAGATNGKDKTSGDNDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS
Protein: Semaphorin 2b, isoform D (A0A0B4KG38)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Plexin-B
- Plexin A, isoform A
- Semaphorin-1A
Sequence:
MPLNAQLKIAQSVNKVTYAKVSDSNCCAKKQQKYSIADFSQAKRQAGSMCATGKGKHRLCSLSALLLVLVAQTVHVEYARADYENTWNLYYEPPCCTGSSAAHHLRHHKEHVQDFSCGPLHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIRVIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVPGIGLGIGKCPYDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEIGEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNCSISSEFPFYFNEIQSVYKMPTDDTKFYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEPRPGTCHNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDVILTKLVVDKIRIDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIFEASPHSEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRCVSDPYCGWDKDVNACRPYQLGLLQDVANETSGICDTSVLRKKVTSSYGQTLHLSCFVKMPEVLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRYDSYLDGTLLCSYGVTVDAHRCSPPSQKQDYQKIYSHWCNEFEKYKSAMKQWQAKQEQCGLKDKTGPISSNGKHVNDVFSNDALVXPRKYLYSFEFLSSATEGVASAHRKLYIFVFVLTIFARF
Protein: At1g78130 (Major facilitator superfamily protein) (Putative transporter; 34935-36578) (Transporter like protein) (Q9C9R9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- TPR repeat-containing protein ZIP4
- Zinc transporter 7
- Metal transporter Nramp6
Sequence:
MKAETMTLLLVNLAGIMERADESLLPGVYKEVGLALHTDPTGLGSLTLLRSMVQAACYPLAAYMAIRHNRAHVIALGAFLWSAATFLVAFSSTFFQVAVSRALNGIGLALVAPAIQSLVADSTDDANRGTAFGWLQLTANIGSILGGLCSVLIAPLTFMGIPGWRVAFHIVGVISVIVGVLVRVFANDPHFVKDGVDVSNQPGSRKPFCTEVKDLVREADTVIKIRSFQIIVAQGVTGSFPWSALSFAPMWLELIGFSHGKTAFLMGLFVAASSLGGLFGGKMGDFLSTRLPNSGRIILAQISSASAIPLAAILLLVLPDDPSTAAIHGLILVLLGLFVSWNAPATNNPIFAEIVPEKSRTSVYALDKSFESILSSFAPPIVGILAQHVYGYKPIPEGSSRSTEIATDRENAASLAKALYTSIGLPMAACCFIYSFLYRSYPLDRDRARMEAFIDSEMRELLPESSNRDIEFSQEEDPFANHVNPNLQAR
Protein: Ribonuclease 7 (Q9R126)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGPKLLESQLCLLLMLGLVLMLASCQRPTASQWFATQHITYKANLQCNVEMQAINMHRPRCKGLNTFLHTSFINVVGVCGNPSGLCSDKISQNCHNSSSRVPITVCNLTTPGRNYTQCRYQTKGSVEYYTVACEPRVAWDCPIYPVVPVHLDGTF
Protein: Spore photoproduct lyase (EC 4.1.99.14) (P37956)
Organism: Bacillus subtilis (strain 168)
Function: Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5,6-dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines.
Interaction partners:
- Transcriptional regulator SplA
- UV DNA damage endonuclease
Sequence:
MQNPFVPQLVYIEPRALEYPLGQELQDKFENMGIEIRETTSHNQVRNIPGKNHLQQYRNAKSTLVIGVRKTLKFDSSKPSAEYAIPFATGCMGHCHYCYLQTTMGSKPYIRTYVNVEEILDQADKYMKERAPEFTRFEASCTSDIVGIDHLTHTLKRAIEHFGQSDLGKLRFVTKFHHVDHLLDAKHNGKTRFRFSINADYVIKNFEPGTSPLDKRIEAAVKVAKAGYPLGFIVAPIYIHEGWEEGYRHLFEKLDAALPQDVRHDITFELIQHRFTKPAKRVIEKNYPKTKLELDEEKRRYKWGRYGIGKYIYQKDEEHALREALESYIDTFFPNAKIEYFT
Protein: Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (F1M625)
Organism: Rattus norvegicus (Rat)
Function: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62068}. Note=USP46/WDR48/WDR20 complex is predominantly cytoplasmic. {ECO:0000250|UniProtKB:P62068}.
Interaction partners:
- WD repeat-containing protein 48
- WD repeat-containing protein 20
- Ubiquitin-ribosomal protein eL40 fusion protein
- PH domain leucine-rich repeat protein phosphatase 1
- Polyubiquitin-C
- Coiled-coil domain containing 183
- PH domain leucine-rich repeat-containing protein phosphatase 2
Sequence:
MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENSKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE
Protein: Metacaspase (Q8T8E8)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MSSEKVAGYVQCVVGIIFGVVTGGASIYVTIAMELLQVAVPYVLVTLGLQRRPPKGGVDKAMAEAESVEAEVMKKPSKQQRSFRALFIGIDYKGTPAELRGCQADAVMMAGTMEKIGIPITERCVLMDTDDPRFNAIKPTRANILQHMAWLVKDAKPGDALFLHYSGYGAQVRAEEDKEEEFDQCIVPCDYEENGCILDNELHEIISTLPRGVRLTAVFDCSHAGTLLDLPFSLICSSNDCSAVGEMKRIRTGGDVNAHVLMFSACGDDEAAADLPNAGDFVEGASGSGGAATQCFISMLLNKTPGTIYSLLSTTRDKLREKGFKQSPQMSASRCLSLTEKFTLTELFSVAEPCPNILTGEPRWKTTPLGGK
Protein: Probable protein phosphatase 2C 67 (AtPP2C67) (EC 3.1.3.16) (Q501F9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Dephosphorylates and represses plasma membrane H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), thus influencing negatively plant growth and fitness. Promotes the apical hook maintenance of etiolated seedlings.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24858935}; Peripheral membrane protein {ECO:0000269|PubMed:24858935}.
Interaction partners:
- Probable protein phosphatase 2C 5
- At3g08760
- E3 ubiquitin-protein ligase APD4
- E3 ubiquitin-protein ligase APD3
- Transmembrane protein
- At5g65580
- Transmembrane protein
- Transmembrane protein
- Transmembrane protein
- E3 ubiquitin-protein ligase APD2
Sequence:
MVKPCWRIGAGMERSKINPTKVDGLTWYKDLGLHTFGEFSMAMIQANSVMEDQCQIESGPLTFNNPTVQGTFVGVYDGHGGPEASRFIADNIFPKLKKFASEGREISEQVISKAFAETDKDFLKTVTKQWPTNPQMASVGSCCLAGVICNGLVYIANTGDSRAVLGRSERGGVRAVQLSVEHNANLESARQELWSLHPNDPTILVMKHRLWRVKGVIQVTRSIGDAYLKRAEFNREPLLPKFRLPEHFTKPILSADPSVTITRLSPQDEFIILASDGLWEHLSNQEAVDIVHNSPRQGIARRLLKAALKEAAKKREMRYSDLTEIHPGVRRHFHDDITVIVVYLNPHPVKTNSWASPLSIRGGYPMHSTS
Protein: Rad, Gem/Kir family member 3, isoform C (Rad, Gem/Kir family member 3, isoform F) (Rad, Gem/Kir family member 3, isoform G) (Rgk3) (A8DYK6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVDDISPMHHRMQKKTRSASICATGASIETVIHGMPGASGSATPEGGTPGYRRRRPATRSQSARITSGARSVRQKTKAQQQQQQQQHTLQETRSYCTSEPRLSETETPPQRRKLSQRRPQTHAHRKSNAFLDVPTMNMHHLRVNDDDEDVDRLRTFSASKGGIINRGDSFRRRRSRSNSLAPSSPMHTRNGVGGLGGVAGGGSSLGLGCGYNGGSSSNGFGNANAQENHQPVEFYRVEMLGSAGVGKQALLSQFRTSDCINAYDGPECDDAEQNVSIILNGTESELKFLTGNPESKDELEQADAFLVVYSCIDKESFTRAKQILSRLQDMDLLRHRPTILVANKIDLARSRAVSAQDGKCVACTFGAKFIEVSVGINHNCDELLAGTLTQIRLKKDQVQLQGPRDANSPAHWYKSRSVMLASMKARQMLTWILGKEDSKFKHCENLQVL
Protein: Solanidine UDP-glucose glucosyltransferase 1 (EC 2.4.1.-) (P93789)
Organism: Solanum tuberosum (Potato)
Function: Glucosyltransferase involved in the glucosylation of the steroidal alkaloid aglycons solanidine, solasodine and tomatidine to produce their corresponding glycoalkaloids.
Interaction partners:
Sequence:
MVATCNNGEILHVLFLPFLSAGHFIPLVNAARLFASRGVKATILTTPHNALLFRSTIDDDVRISGFPISIVTIKFPSAEVGLPEGIESFNSATSPEMPHKIFYALSLLQKPMEDKIRELRPDCIFSDMYFPWTVDIADELHIPRILYNLSAYMCYSIMHNLKVYRPHKQPNLDESQSFVVPGLPDEIKFKLSQLTDDLRKSDDQKTVFDELLEQVEDSEERSYGIVHDTFYELEPAYVDYYQKLKKPKCWHFGPLSHFASKIRSKELISEHNNNEIVIDWLNAQKPKSVLYVSFGSMARFPESQLNEIAQALDASNVPFIFVLRPNEETASWLPVGNLEDKTKKGLYIKGWVPQLTIMEHSATGGFMTHCGTNSVLEAITFGVPMITWPLYADQFYNEKVVEVRGLGIKIGIDVWNEGIEITGPVIESAKIREAIERLMISNGSEEIINIRDRVMAMSKMAQNATNEGGSSWNNLTALIQHIKNYNLN
Protein: Pyrimidine pathway regulatory protein 1 (P07272)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Positive regulator of URA1 and URA3 expression.
Subcellular location: Nucleus.
Interaction partners:
- Dihydroorotate dehydrogenase
- Dihydroorotase
- Orotidine 5'-phosphate decarboxylase
- Orotate phosphoribosyltransferase 1
- Orotate phosphoribosyltransferase 2
- Regulatory protein LEU3
- Histone-lysine N-methyltransferase SET5
- Regulatory protein GAL4
Sequence:
MKQKKFNSKKSNRTDLSKRGDSPNIGISKSRTACKRCRLKKIKCDQEFPSCKRCAKLEVPCVSLDPATGKDVPRSYVFFLEDRLAVMMRVLKEYGVDPTKIRGNIPATSDDEPFDLKKYSSVSSLGEEGILPHNGLLADYLVQKGNSMASSAITSKSMASPQTINVQRKEFLVNSKKQDGSALLPETGSPMTSDARAEELRRCNKEISALGTMRESSFNSFLGDSSGISFAKLVFTATNFRQDSGDDVLDEDIKQREQKYNGYAEAENNPHFDPLELPPRHAAEVMISRFFVDTNSQLPLLHRELFLKKYFEPIYGPWNPNIALASDQTGINSAFEIPITSAFSAHTEPKRENVTEKIDVCSSVDVPWYDTWETSQKVNMRPIVELPTKFHIPYFFLNIIFAIGHATQVLKSDITTVATYKRRATKYIASLFSSSDRLEALAGTLLMVIYSIMRPNVPGVWYTMGSVLRLTVDLGLHSEKINKNYDAFTREIRRRLFWCVYSLDRQICSYFGRPFGIPEESITTRYPSLLDDSFITLTNREIDDYSDLPSPNPSSKVIALAMYKIRRIQASIVRILYAPGAELPRRFMDLESWRIETYNELERWFQVDVPKNFEMMNCKFNSIWFDLNYHYSKSILYGLSPKFPTLNDTAFKIVLDSTKGTIDVFYNLCVNKKIGYTWVAVHNMFMTGMTYLYVNFYSKNNINDCQEKVSEYTEKVLIVLKNLIGFCESAKTCYTSYKILSSVVIKLKFMQINDAKGIFSDSNPLTSQANRMSSYDKKTNVLGFDDGTFDNKVFNRTNFEEKAPFDIPLDEFFTELEKHSNVSQFNTLDVSEGNQVINESASTNTSSALNCQSYTNNQDIMDILFQVTSGSVWDEFFVRSGNGNEGESSYDISKGKNSESGGIF
Protein: High mobility group protein B1 (High mobility group protein 1) (F2Z594)
Organism: Sus scrofa (Pig)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004296}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004296}; Extracellular side {ECO:0000256|ARBA:ARBA00004296}. Chromosome {ECO:0000256|ARBA:ARBA00004286}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000256|ARBA:ARBA00004399}. Endosome {ECO:0000256|ARBA:ARBA00004177}. Nucleus {ECO:0000256|ARBA:ARBA00004123}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVIKAEKSKKKKKMMMMNKLVLAQFFFLVYKAFNPPVHNSLLLKKKN
Protein: Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (A0A0S2Z4R1)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRVSYYENVIKAMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPMAKGPAKNSEPEEVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS
Protein: ABCB9 protein (Q6P2Q0)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLSPQIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA
Protein: IAA-amino acid hydrolase ILR1-like 6 (EC 3.5.1.-) (Protein gr1) (jasmonoyl-L-amino acid hydrolase) (EC 3.5.1.127) (Q8VYX0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA). Also hydrolyzes amino acid conjugates of jasmonic acid and 12-hydroxy jasmonic acid.
Interaction partners:
- Cytochrome P450 94B1
- Cytochrome P450 94B3
- Cytochrome P450 94C1
- Protein LONG AFTER FAR-RED 3
- Cytosolic sulfotransferase 15
- 12-oxophytodienoate reductase 3
Sequence:
MDNLRKLNLLSVSLTIIFVSLTIATNLPFFEVKYPNNNPFGMLLRPTPIKNQSLGLPAHVGSDECRVWTKACSDEILRLTYQPDNVAWLKRVRRTIHENPELAFEEYETSRLIRSELDRMGIMYRYPLAKTGIRAWIGSGGPPFVAVRADMDALPIQEAVEWEHISKVAGKMHACGHDAHVTMLLGAAHILKAREHLLKGTVVLLFQPAEEAGNGAKNMIEDGALDDVEAIFAVHVSHIHPTGVIGSRSGPLLAGCGIFRAVITSEDSRGAANLLLAASSAVISLQGIVSREASPLDSQVVSVTSFDGGHSLDVAPDTVVLGGTFRAFSNSSFYYLKKRIQEVLMDQVGVFGCQATVNFFEKQNAIYPPTTNNDATYNHLKKVTIDLLGDSHFTLAPQMMGAEDFAFYSEIIPAAFYFIGIRNEELGSVHIAHSPHFMIDEDSLPVGAAVHAAVAERYLNDKHS
Protein: HTH-type transcriptional regulator PerR (Peroxide resistance protein PerR) (Q57083)
Organism: Escherichia coli (strain K12)
Function: Apparent regulatory gene involved in peroxide resistance in stationary phase.
Interaction partners:
- DNA-binding transcriptional dual regulator OxyR
- Transcriptional regulator MntR
- Redox-sensitive transcriptional activator SoxR
- Uncharacterized protein YkfA
- PTS system fructose-like EIIA component
- Alkyl hydroperoxide reductase C
- Hca operon transcriptional activator HcaR
Sequence:
MKLLAKAPLNLLRAFEAAGRTGAFALAASELELSPSAISHAIRKLENLLDVRLFQRSTREITLTKEGEILLEHIQRGFNELQQGLALVTADESRPLRLHTAPSFAHQWLLPRLGKFIRENPSIDLRLSASTEYARFEQDDFDLDIVYGEPRPSPYEKIPLAVEELTPLCSPQLAERLKKPEDLYALTLIQCDVQLYQWKGWFEANKMTPPNNYGLRFDRSFMAIAAAVDGLGVVLESKLLAEREIASGKLVCPLVNSTSEIHYIGHYLVFPQHQHMHSALDVFKTWLLNELNLGKIR
Protein: Meis homeobox 2a (Meis2.1 protein) (Myeloid ecotropic viral integration site 2.1) (Q9DDE0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
- tRNA methyltransferase 1-like
- Transporter
- Teashirt zinc finger homeobox 3b.
- Teashirt homolog 2 isoform X2
Sequence:
MLMAQRYEDLAHYGGGMDGVGVPTSMYGDPHAPRPLPQVHHLNHGPPPHANQHYGAHAPHSIMPSSMGSAVNDALKRDKDQIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQSIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGCKSDFDDLSGSSTNLADHNPASWRDMDDAHSTPSVGTPGPSSGGHASQSGDNSSELGDGLDNSLASPGTGDEDDQDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTAYSPDGQPMGGFVLDGQQHMGLRPGGPMGGMGMNMGMDGQWHYM
Protein: Vacuole membrane protein 1 (Q91ZQ0)
Organism: Rattus norvegicus (Rat)
Function: Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes (By similarity). Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine (By similarity). Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by ATG2 (ATG2A or ATG2B) to mediate autophagosome assembly (By similarity). Regulates ATP2A2 activity to control ER-isolation membrane contacts for autophagosome formation. In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required (By similarity). Modulates ER contacts with lipid droplets, mitochondria and endosomes (By similarity). Plays an essential role in formation of cell junctions (By similarity). Upon stress such as bacterial and viral infection, promotes formation of cytoplasmic vacuoles followed by cell death. Involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:11785947}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q96GC9}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000269|PubMed:17940279}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q96GC9}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with MAP1LC3A and BECN1. {ECO:0000269|PubMed:17940279}.
Interaction partners:
- Beclin-1
- Autophagy related 13
- Tumor protein p53-inducible nuclear protein 2
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Ubiquitin-like protein ATG12
- Autophagy protein 5
- Transmembrane protein 41B
- Ubiquitin-like modifier-activating enzyme ATG7
- Beclin 1-associated autophagy-related key regulator
- Ubiquitin-like-conjugating enzyme ATG3
Sequence:
MAENGTNCDQRRGAMSKEQHNGSFTDPSSVNEKKRRDREERQNIVLWRQPLITLQYFSLETLVVLKEWTSKLWHRQSMVVSFFLLLAALVATYYVEGAHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGAISLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAETAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIVTFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHRSEAGTAQGENWLSWTFEKLVVAMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK
Protein: Chromosome 19 open reading frame 47 (J3QKZ5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFVDNRIQKSMLLDLNKEIMNELGVTVVGDIIAILKHAKVVHRQDMCKAATESVPCSPSPLAGEIRRGTSAASRMITNSLNHDSPPSTPPRRPDTSTSKISVTVSNKMAAKSAKATAALARREEESLAVPAKRRRVTAEMEG