wanglab/gogpt-training-data huggingface dataset:
Protein: Pyruvyl transferase 1 (EC 2.-.-.-) (Pyruvylated Gal-beta-1,3-epitope synthesis protein 1) (PvGal synthesis protein 1) (Q9UT27)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moieties to galactomannans and their subsequent pyruvylation.
Interaction partners:
- Putative transporter C83.11
- Beta-1,3-galactosyltransferase pvg3
- Pyruvylated Gal-beta-1,3-epitope synthesis protein 5
- O-glycoside alpha-1,2-mannosyltransferase omh1
- Uncharacterized protein C19C7.05
- Probable glycosidase C21B10.07
- Uncharacterized transporter C22F8.04
Sequence:
MFANINIRKSVWLFLLAAVSCTLFIYGVTRTDLQTLKNPSSLTSPSSSTSVDKKKPLFTKSPRNSASCESTITLQSNLLFTYYKHYFAGIKKVALIGFPDHPNKGDSAIYVAEKKLLDALNIEVVYITAQEADYSASELKSIISDIPRDEFALAFHGGGNFGDLYPDHQHLRELVVRDFPSFTTISFPQSVWYNEQQLLEQASILYAENPNITLVTRDRQSYGFAVDAFGKHNEVLLTPDIVFFMGPIPEIREATPITHDVLILARLDHEGGQQHGAEDYYRDTLNAANLTYSVEDWLLWDPPVAQNPDSSFDDRGQARYEAGAEFLASARVVITDRLHAHILSTLMGIPHIVVENSQMGKITNYHNTWLHGCTLDGVSVVVDSVDKALSLLLEWNEAGYF
Protein: Protein SREK1IP1 (SFRS12-interacting protein 1) (SREK1-interacting protein 1) (Splicing regulatory protein of 18 kDa) (p18SRP) (Q8N9Q2)
Organism: Homo sapiens (Human)
Function: Possible splicing regulator involved in the control of cellular survival.
Interaction partners:
- Splicing regulatory glutamine/lysine-rich protein 1
Sequence:
MAVPGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK
Protein: Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog) (P15170)
Organism: Homo sapiens (Human)
Function: Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activity of ETF1 (By similarity). Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
Interaction partners:
- Eukaryotic peptide chain release factor subunit 1
- Polyadenylate-binding protein 1
- Regulator of nonsense transcripts 1
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3B
- Protein cereblon
- Small ribosomal subunit protein uS12
- Serine/threonine-protein kinase SMG1
- Large ribosomal subunit protein eL21
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS19
Sequence:
MELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
Protein: Combgap, isoform L (A8DYD1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MCAAQNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGLTAGGKNNVVRRMFVVNDPSFPPGTQRVITAGGASTVVKKQDNNQQVLSLDKNYLLVDPATAAAAAAAAGGDSGLAHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGSHHHASGGTPSFCSVGGATTLLGDILPGISVQVQKVIQGLEDNEDSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEAATQQQLATAGEQQQVQVQIMPDGQIHGKVIKYEICRNVMPEDQQQEQADMNAE
Protein: Transient receptor potential cation channel, subfamily C, member 7 (F1LQF7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Short transient receptor potential channel 3
- Transient receptor potential Ca2+ channel 6A
Sequence:
MLGSNTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNLQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSVFVASFTARFMAFLKASEAQLYVDQYVQDVTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKRCENDLEMGMLNSKFRKTRYQAGMRNSENLTANSTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI
Protein: Niemann-Pick type C-2g, isoform A (Niemann-Pick type C-2g, isoform B) (Q9VA42)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Niemann-Pick type C-2c
- GEO07678p1
- Niemann-Pick type C-2e
- NPC intracellular cholesterol transporter 2 homolog a
- GEO08227p1
- Niemann-Pick type C-1a, isoform A
- NPC intracellular cholesterol transporter 1 homolog 1b
- LP08842p
- GEO07291p1
- GH14572p
Sequence:
MLRPSSLQAVAIAIVLISSSASAEVVNFEPCPDSVDTCTIQQVRVSPCPEALNNAACNIRRKHNSEMSFDFTPNFDADTLVASLGWAKSENVELPLLTLDSAACKYTPCPVRSGVKQTYTTLVPIEAKFPLSPYTIRWALKDPVSQKRCCFTIDIKVVR
Protein: Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (Q8JIU7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May promote appropriate targeting of ribosome-nascent polypeptide complexes.
Interaction partners:
- Transcription factor BTF3
- Small ribosomal subunit protein eS1
- Ribosomal protein L18
- Large ribosomal subunit protein eL19
- 60S ribosomal protein L7a
- Large ribosomal subunit protein uL23
- Transcription factor BTF3 homolog 4
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL20
- Large ribosomal subunit protein uL22
Sequence:
MPGEATETVPVTEQEMQQPQAETGSGTESDSDESVPDLEEGDSAQTQTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVAGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNNNDIVNAIMELTM
Protein: Testis-specific protein TEX28 (O15482)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Transketolase-like protein 1
- Long-wave-sensitive opsin 1
Sequence:
MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP
Protein: PDZ domain-containing protein (Q20398)
Organism: Caenorhabditis elegans
Interaction partners:
- Protein lin-2
- Tetratricopeptide repeat protein 28
- Trifunctional purine biosynthetic protein adenosine-3
- PDZ domain-containing protein
- Protein dct-6
- Adenine phosphoribosyltransferase
- PDZ domain-containing protein
Sequence:
MVEVEAKPSSLSVEEDENENEEEKLEDVEKEKLVKQLKFEKAERRRIAEEMEKEIREVEAKWMEKVRKASEERDDIGKKIDEFEEKIDSLQIQVHRSETYKMEIEEANKRLRLQYEALQRDYEETMQERSIVLEENSRQNEERDRLQKEIEKMKEDSEEVAALKQKLENTRRLLKVNMEETAQANARKEAAIARLTEAEQNGARITEERDEALRKCQQTTGDAIVDIWNTHSVQINLPFNKPNLGIMLGGGRTDDGSIVHGPIYVRQIAHGSPFDNVLKKLDHIMMVNDISVTDMDERSVMGMLSNCHHIHLVIRRRSNCNKISDVCLPLNYGVGLELSNGVFINSCEPNGAASRSGLAPGQRVVHVMHTPVYDAKHAEMLIKNSREPLVIGILQSTKRGDHNGKDKHRQTIFSRWFSRNGGSDKERTVVAKANIDRSNDQVLLRQGSLRMPQASPASMSPLVRYGSLRAPTYSSSIDHTKLMLDALDKRFNAKSTAHSEISSSSTAAPTALWSPSSVNEKDLVFAGTNIEGVPVYVPKSTIFSTPTSPVTRLIRQNSEQKRTMSQISSHRGGWDGRSFSSNTTTSDARPYSMHFTPTSSTIMEGKPHRRSAVYSPSHPPVYPTIRDDSMSSVMSSSNSIRLPSTSFSNQYPNNSTCSLTGGSGVPPRHCISKDGSDFSISTTGSAMHSYAEGRSNKKYHLPRGNHHSESLLVNRSSQPRLVEVPRSDVKLCGGNAIGILAEKSIGSDLLEGDLILSIDGNCVRNTTLECAMNTLSADNSELTGLLVQDGGDRLNRLRLGADGDSFFLRVNIDRSMENKDELDLKCGDVVFVDKTMLMGKTGRWRAWKVDKEGRQREHGAIPSSTTVYQAIRANRYANPFPKKAYEWVEKLDTKVKRPVLLFGAVVEPFLQMLVDESDKFSIVARESLTASLDEVSALLKDKVLIDSKQNDDVYDLYHVVSTAHIMDITAQGLHCVLQVDQSAIDRLKRCRMFPILVKIRFKSVKQLKDVNEHICGEKISSKEAKQLIEKDLKIEKDLDGSVTLVVPSHNNVSFMMTHAVLQLKKIIEDEQKKIVWVQRKVDEE
Protein: Large ribosomal subunit protein P2 (60S acidic ribosomal protein P2) (P02401)
Organism: Rattus norvegicus (Rat)
Function: Plays an important role in the elongation step of protein synthesis.
Interaction partners:
- Large ribosomal subunit protein P1
- Large ribosomal subunit protein uL10
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein eL20
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL30
Sequence:
MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD
Protein: Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein ZSIG9) (Transmembrane protein 4) (Q9QXT0)
Organism: Mus musculus (Mouse)
Function: Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity).
Subcellular location: Endoplasmic reticulum {ECO:0000255|PROSITE-ProRule:PRU10138}.
Interaction partners:
- Protein canopy homolog 4
- Protein canopy homolog 3
Sequence:
MKGWGWLALLLGVLLGTAWARRSQDLHCGACRALVDELEWEIARVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEVCDRMKEYGEQIDPSTHRKNYVRVVSRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHRSHDEL
Protein: Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein) (p49/STRAP) (Q8NEF9)
Organism: Homo sapiens (Human)
Function: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity).
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9CZ91}.
Interaction partners:
- Bystin
- Serum response factor
- DNA-directed RNA polymerase, mitochondrial
- WD repeat-containing protein 36
- Periodic tryptophan protein 2 homolog
- U3 small nucleolar ribonucleoprotein protein IMP4
- WD repeat-containing protein 3
- Probable ATP-dependent RNA helicase DDX10
- Nucleolar protein 6
- Uncharacterized protein.
Sequence:
MAQPGTLNLNNEVVKMRKEVKRIRVLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDIVTKSALGDDINFEKIFKKPDSTATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWEASRRRKEQQSNIAVFQGKKITFDD
Protein: RAN GTPase activating protein 1 (A0A8I6AMS6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSKLKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLTLKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVLDSFNMAKVLASLSDDEGEDEDEDEEGEDDEDEEDEEEEEEEEEEEEEEEEEPQQRGSGEEPATPSRKILDPNSGEPAPVLSSPPPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDEASVKTAVLDAIDALMKKAFSSSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVQQDYFPKTLAPLLLAFVTKPNGALESCSFARHSLLQTLYSI
Protein: Calcium-transporting ATPase 1 (EC 7.2.2.10) (Bypass SOD defects protein 1) (Golgi Ca(2+)-ATPase) (P13586)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Has a role in the secretory pathway.
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein.
Interaction partners:
- Calcium-transporting ATPase 2
- Vacuolar calcium ion transporter
- Calcium-channel protein CCH1
- Putative uncharacterized protein HUR1
- Transcriptional regulator CRZ1
- Divalent cation/proton antiporter GDT1
- Stretch-activated cation channel MID1
- Calcipressin-like protein
- Superoxide dismutase
- Manganese transporter SMF1
Sequence:
MSDNPFNASLLDEDSNREREILDATAEALSKPSPSLEYCTLSVDEALEKLDTDKNGGLRSSNEANNRRSLYGPNEITVEDDESLFKKFLSNFIEDRMILLLIGSAVVSLFMGNIDDAVSITLAIFIVVTVGFVQEYRSEKSLEALNKLVPAECHLMRCGQESHVLASTLVPGDLVHFRIGDRIPADIRIIEAIDLSIDESNLTGENEPVHKTSQTIEKSSFNDQPNSIVPISERSCIAYMGTLVKEGHGKGIVVGTGTNTSFGAVFEMMNNIEKPKTPLQLTMDKLGKDLSLVSFIVIGMICLVGIIQGRSWLEMFQISVSLAVAAIPEGLPIIVTVTLALGVLRMAKRKAIVRRLPSVETLGSVNVICSDKTGTLTSNHMTVSKLWCLDSMSNKLNVLSLDKNKKTKNSNGNLKNYLTEDVRETLTIGNLCNNASFSQEHAIFLGNPTDVALLEQLANFEMPDIRNTVQKVQELPFNSKRKLMATKILNPVDNKCTVYVKGAFERILEYSTSYLKSKGKKTEKLTEAQKATINECANSMASEGLRVFGFAKLTLSDSSTPLTEDLIKDLTFTGLIGMNDPPRPNVKFAIEQLLQGGVHIIMITGDSENTAVNIAKQIGIPVIDPKLSVLSGDKLDEMSDDQLANVIDHVNIFARATPEHKLNIVRALRKRGDVVAMTGDGVNDAPALKLSDIGVSMGRIGTDVAKEASDMVLTDDDFSTILTAIEEGKGIFNNIQNFLTFQLSTSVAALSLVALSTAFKLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMKKPPRKRTDKILTHDVMKRLLTTAACIIVGTVYIFVKEMAEDGKVTARDTTMTFTCFVFFDMFNALACRHNTKSIFEIGFFTNKMFNYAVGLSLLGQMCAIYIPFFQSIFKTEKLGISDILLLLLISSSVFIVDELRKLWTRKKNEEDSTYFSNV
Protein: Palmitoyltransferase spe-10 (EC 2.3.1.225) (Defective spermatogenesis protein 10) (Q5FC64)
Organism: Caenorhabditis elegans
Function: Involved in spermatogenesis, specifically in the morphogenesis of fibrous body-membranous organelles (FB-MO), which are Golgi-derived organelles used for transporting sperm-specific components, in spermatocytes and in their localization into budding spermatids. Required for the proper formation of spermatids and spermatozoa.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Mainly found in fibrous body-membranous organelles. {ECO:0000269|PubMed:16143610}.
Interaction partners:
- Spermatogenesis-defective protein spe-17
- Myosin motor domain-containing protein
- Sperm vesicle fusion protein fer-1
- Dendritic cell-specific transmembrane protein-like domain-containing protein
- Spermiogenesis protein SPE-29
- Folate transporter 1
- Presenilin spe-4
- Uncharacterized protein
- Palmitoyltransferase
- SKA complex subunit 1
Sequence:
MSWYSKIYVAVREYRAKHKITGWILTRCLNVLLFIQLILLWWSLYMYVTVTIGYYVQSTIQATIYLIVGSFLFVMSMWSLAKTLFTRVGRVPERYRPSKELEDRLKAVTPMEKNRYVVEKSTPEQLAQQNTILEEMCTYCKVVVAECDQVGRLKYCYECGHIKPDRARHCSSCGKCCIKYDHHCPWINMCVTHVNYKYFLLYIIYTSFLVYWYLLTSLEGAVRYFINQQWTDELGKFLFYLFSFIVGGVFGYYPLGELIIFHYQLISLNETTVEQTKPALLRFDNAADYNMGKYNNFQSVFGWGLWLCPIDSSTQDGLHFDIRYVNTQQRNRFVRIEEEPSSTQSSQSSIQ
Protein: BCL-6 corepressor (BCoR) (Q8CGN4)
Organism: Mus musculus (Mouse)
Function: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2) (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:12776190}.
Interaction partners:
- Polycomb group RING finger protein 1
- B-cell lymphoma 6 protein homolog
- E3 ubiquitin-protein ligase RING2
- E3 ubiquitin-protein ligase RING1
- Protein AF-9
- Lysine-specific demethylase 2B
- Polycomb group RING finger protein 6
- Chromobox protein homolog 8
- RING1 and YY1-binding protein
- Polycomb group RING finger protein 3
Sequence:
MLSATPLYGNVHSWMNSERVRMCGTSEDRKIPVNDGDASKARLELREETPLSHSVVDTSGAHRIDGLAALSMDRTGLIREGLRVPGNIVYSGLCGLGSEKGREATPSSLSGLGFSSERNPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAESLGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYGLAQPLYSPVCTSGERFLYLPPPHYVNPHIPSSLASPMRLSTPSASAAIPPLVHCSDKSLPWKMGVNPGNPVDSHSYPHIQNSKQPRVTSAKAVNSGLPGDTALLLPPSPRPSARVHLPTQPAAETYSEFHKHYPRISTSPSVTLTKPYMTANSEFSTSRLSNGKYPKALDGGDCAQSMPGHTRKTTVQDRKDGGSPPLLEKQTVTKDVTDKPLDLSSKVVDADASKGDHMKKMAPTVLVHSRAASGLVLSGSEIPKETLSPPGNGCSIYRSEIISTAPSSWVVPGPSPNEENNGKSLSLKNKALDWAIPQQRSSSCPRMGGTDAVVTNVSGSVSSSGRPASASPAPNANANADGTKTSRSSVDTTPSVIQHVGQPSSTPAKHGGSTSSKGAKANPEPSFKASENGLPPTSIFLSPNEAFRSPAIPYPRSYLPYAAPEGIALSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLHTSRPEFVTYQDALGLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRSRFSEMLEASSTKLHPEVPTDKNLKPNSSWNQGKTGVKSDKLVYVDLLREEADTKTDAGAPKAGLVAENVGQDTEATKPSADPVIQQRREFISLREELGRITDFHESFTFKQASSQPVFSLGKDSGAAGTNKENLGVQVATPFLETALGSEGPAVTFGKTQEDPKPFCVGGAPPNMDVTPAYTKEGTDEAESNDGKVLKPKPSKLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAMMRFSELEMKEREGSHPATKDSEVCKFSPADWERLKGNQEKKPKSVTLEEAIADQNDSERCEYSTGNKHDLFEAPEDKDLPVEKYFLERPPVSEPPSDQGVVDTPHSPTLRLDRKRKLSGDSTHTETAVEELAEDPLKAKRRRISKDDWPEREMTNSSSNHLEDPHCNELTNLKVCIELTGLHPKKQRHLLHLRERWEQQVSAAESKPGRQSRKEVAQAVQPEVTSQGTNITEEKPGRKKAEAKGNRGWSEESLKSCDNEQGLPVLSGSPPMKSLSSTNASGKKQTQPSCTPASRLPAKQQKIKESQKTDVLCTGEDEDCQAASPLQKYTDNIEKPSGKRLCKTKHLIPQESRRSLQITGDYYVENTDTKMTVRRFRKRPEPSSDYDLSPPAKQEPKPFDRLQQLLPATQATQLPRSNSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKVCDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRSEDDTSGAWEFYGSSVCEPDDESGYDVLANPPGPEDPDEEEDTYSDLFEFEFAESSLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRSNFPNLEIVTIAEAEFYRQVSTSLLFSCPKDLEAFNPESKELLDLVEFTNELQTLLGSSVEWLHPSDTGHENYW
Protein: GDT1-like protein 3 (Q93Y38)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative DNA
- Calcium-transporting ATPase 3, endoplasmic reticulum-type
- Calcium-transporting ATPase 1, endoplasmic reticulum-type
Sequence:
MGLISNPTRLILVATIFFLVSSISGQDSVVENNERQESEGSGKELGRRGMVGTERIGVDTVVDNIGALGLNLDLDATAPSVFDALFSSFSMILVTEIGDETFIIAALMAMRHPKATVLSGALSALFVMTILSTGLGRIVPNLISRKHTNSAATVLYAFFGLRLLYIAWRSTDSKSNQKKEMEEVEEKLESGQGKTPFRRLFSRFCTPIFLESFILTFLAEWGDRSQIATIALATHKNAIGVAIGASIGHTVCTSLAVVGGSMLASRISQRTVATVGGLLFLGFSVSSYFYPPL
Protein: Myotubularin-related protein 9 (Inactive phosphatidylinositol 3-phosphatase 9) (Q965W9)
Organism: Caenorhabditis elegans
Function: May act as a regulatory subunit for mtm-6. In association with phosphatase mtm-6, plays a role in endosome trafficking probably by regulating phosphatidylinositol-3-phosphate levels. Regulates fluid phase endocytosis in coelomocytes. Regulates posterior migration of QL neuroblast descendants and the anterior migration of QR neuroblast descendants and HSN neurons during larval development probably by controlling Wnt ligand secretion through the regulation of sorting receptor mig-14 trafficking. Involved in the formation of correct synapse number in DA9 motor neurons.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14565969}. Membrane {ECO:0000269|PubMed:14565969}; Peripheral membrane protein {ECO:0000269|PubMed:14565969}.
Interaction partners:
- Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6
- SAC domain-containing protein
Sequence:
MELSELIEVTRVRDAFMRKGPRPAQVGDICIFGHHLIFAPTTVGKEVPDNAEEFWLLHKAVDRVLCEPISKENPQRGGLLALKCKNFLLIIFEIGDLEICRATARTIESLSNINGFLHDYAFFYNSPFTILDDGWSAFDLEQEFARLMLSTDAFRISSVNENFAICPTYPEKLIVPKGIGDDYLKISATFREGGRFPVLSYFHKETKSPLVRCSQPLIGPTNRRCREDETILNSMITVNRGYIIDTRSKSSATAAKAKGGGAEPQGNYRQWRYIQCPIPRQREIHDALTRMVDVCSERKVTSDRWVSRVGQAGWLSSVAASLEAAANVAQCIYNERLEEVPVVIHGGDGLDSTLIASSLAQILLDADARTIRGFESVIEREWICGGHPFSLRNNHCAYAEGTVTGPFESPVFLVFLDAVHQMIAQYPMSFEFDENFLIFLFEHAYASEFGSFLGNCEKEKKDNGIRKKTVSLWSHVHHPENMKQFVNVCYDPTPGVIWPSIAPQCIKIWDRLFFRWQRPDNSWSTPETETIQSLADHWKLREKELIAKASSLRRSVVELSRELRVLSPM
Protein: Solute carrier family 35 member G1 (Partner of STIM1) (Transmembrane protein 20) (Q2M3R5)
Organism: Homo sapiens (Human)
Function: May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22084111}; Multi-pass membrane protein {ECO:0000269|PubMed:22084111}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22084111}; Multi-pass membrane protein {ECO:0000269|PubMed:22084111}. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane.
Interaction partners:
- Stromal interaction molecule 1
- Store-operated calcium entry-associated regulatory factor
- Calcium release-activated calcium channel protein 1
Sequence:
MRPQDSTGVAELQEPGLPLTDDAPPGATEEPAAAEAAGAPDRGRCWLCLSSPCCSRTEPEAKKKAPCPGLGLFYTLLSAFLFSVGSLFVKKVQDVHAVEISAFRCVFQMLVVIPCLIYRKTGFIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKEKYSPWDALFTVFTITGVILIVRPPFLFGSDTSGMEESYSGHLKGTFAAIGSAVFAASTLVILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLGEWSLPYCGLDRLFLIFIGLFGLGGQIFITKALQIEKAGPVAIMKTMDVVFAFIFQIIFFNNVPTWWTVGGALCVVASNVGAAIRKWYQSSK
Protein: Nuclear control of ATPase protein 2 (O74963)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase.
Subcellular location: Mitochondrion membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- ATPase synthesis protein 25
- Large ribosomal subunit protein bL27m
- Probable secretory pathway GDP dissociation inhibitor 1
- Rab guanine nucleotide exchange factor sec2
- Guanine nucleotide exchange factor MSS4 homolog
- GTP-binding protein ypt1
- Vacuolar fusion protein mon1
- Altered inheritance of mitochondria protein 19 homolog
- Vacuolar calcium ion transporter
- Probable vacuolar protein sorting-associated protein 16 homolog
Sequence:
MELYQKHLKDVYANFNKLAAVHGETTSNSVTFHVFQQLDSTNLTNYQLENVITQVKELDKGPKDYLYWVILGRCSAHLHVKMLDQLLEEAMIMSDNLHYWESIDKNWYSRVLFLIQSFPTRLYHICRNSIKSILQFQNFSNIFAKKNLFPKVSKSDVLLFPRDAFISQASLLSLIRHEYRGNAKRLRQLRDEHACKIGCLTRAIMSEGVSDAASSSGDKNGISAKADLKQVVSQWIQRLSQLQGQKIDNSESLPDILSITLDNLSHPTDEYFEAKAYFRPSAIERNWPKIFVTLLSAWLSTQIITKNRTSIRLWIDYLYSTAVDFYTNWIQKPILGIFDTIRSNRADSQITLLQTKSLESDMESLQRMVIDFVSDTSPAGINLDLVKQEVQQGDLTYVLQAYEHDLKTPIRTAVSGNLVRTLLIQLQKTKVDVEVALSGIDRLLKSQELVFATVGITPSLIFCYVIIRYVKANIFNNDTLSRAERRQRFRQSLRAAERILVRSQKMNSLDDMSYGLLVFQVNLMAIMSMDMGLSKDVAEDLLQDLEDIQSSSYGVQAQLRAVDRIYRLFKNSI
Protein: G-protein alpha subunit (Q8RYB4)
Organism: Phytophthora infestans (Potato late blight agent) (Botrytis infestans)
Interaction partners:
Sequence:
MGLCASQMNDNDRQAMAKSREIEAKNEEAHRVEQEKVKLLLLGAGESGKSTVFKQMKILFGAALTEDEKRHCTPIIYNNVVTSMKMLIEQCAEMKLKGDVVCVQDFEDIRTLSDEAEVNLVIGQKIKNLWSDPGIVATWNRRAEFQIIESVKYYFNDLDRIMRDDYAATQQDMLYARVRTSGIVEERYQIDGATFVMYDVGGQRNERKKWIHCFEDVTAVIFVAALSEYDQSLYEDASTNRMIEAITLFDEIINNKFFLNSAMILFLNKKDLFQDKIKKVDPKTVEVFKDFPGGIGDYELGVQYFLGKFMEMNRQPEKEIYHHVTCATDSQNVQVVFNACKDIILKQNIKGSGFM