wanglab/gogpt-training-data huggingface dataset:
Protein: Amyloid-beta A4 protein (B0V0E5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU367156}; Single-pass type I membrane protein {ECO:0000256|RuleBase:RU367156}. Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MGMDRTVFLLLMLTTLSLAIEVPSDDSVGLLAEPQVAMFCGKLNMHINVQSGKWEPDPTGTKSCISTKEGILQYCQEVYPDLQITNVVEANQPVSIQNWCKMGRRQCRSHTHIVVPYRCLVGEFVSDALLVPDKCKFLHQERMDMCESHLHWHTVAKESCGDRSMNLHDYGMLLPCGIDRFRGVEFVCCPMEEQKDLDSEEQEEANSDVWWGGAETEYTDASVLKEQVTAKPDPAVTEDDEDLNNEEDQVWDNDEDGDGEDDEDEEDDDEDIIDEQDTSEQTSNIAMTTTTTTTTESIEEVVRAVCWAPARSGPCHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYCMAVCSSSVLPTMAPSPADAVDRYLEAPGDINEHMRFQKAKESLEAKHREKMSEVMREWEEAERQAKNLPRADKKTIIQRFQEKVESLEKEAAGERQQLVETHMARVEALLNDRRRQALESYLSSLQSDQPRPRQVLNLLKKYIRAEQKDRQHTLKHFEHVREVDPKKASQIRPFVMTHLRVIEERMNQSLGYLYKVPQVANDIQDQVAVLVQRDQAEVTQQLSSLQSKMRVSYGNDALMPDLPDSTTPLDNLPPEQDGLGFIHPESFNQANTDNHVEPVDARPIPERGLPTRPEIPKVRLDIEERHNAGYDVRDKRLMFLAEDMGSNKGAIIGLMVGGVVIATVIVITLVMLRKKQYTSIHHGVIEVDAAVTPEERHLAKMQQNGYENPTYKFFEQMQN
Protein: Sk-tropomodulin (Q9PUQ7)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MTSYRQELEKYRDIDEDKILQELSAEELEQLDTELLEMDPENVLLPAGLRQRDQTQKSPTGPLDREALLQHLEKQALEAKEREDLVPFTGEKKGKPFVPKNPTREIPREEQITLEPELEEALANATEAEMCDIAAILGMYTLMSNKQYYDAICSGTITNTEGINSVVKPDKYKPVPDEPPNPTNVEETLRQIQANDSALEDVNLNNIKDIPISTLKAICEAMKTNTHVKKLSLVATRSNDPVATAVAEMLAENKTLQSLNIESNFITSAGMMSVIKAMYQNSTLSELKVDNQCQRLGNTVEMEMATMLEQCPSVVRFGYHFTQQGPRARAAIAITRNNELRRKQKKT
Protein: Proteasome subunit beta type-7-A (EC 3.4.25.1) (20S proteasome beta subunit B-1) (Proteasome component FA) (Proteasome component FB) (Proteasome subunit beta type-2) (O23710)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular location: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
Interaction partners:
- Proteasome subunit beta type-1
- Proteasome subunit alpha type-3
- Proteasome subunit beta type-6
- Proteasome subunit alpha type-6-B
- Proteasome subunit beta type-4
- Proteasome subunit alpha type-1-A
- Proteasome subunit alpha type-5-A
- Proteasome subunit alpha type-6-A
- Proteasome subunit beta type-2-B
- Proteasome subunit alpha type-7-A
Sequence:
MSQSTVDVPPKGGFSFDLCKRNDMLTQKGLKAPSFLKTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSRVITALTLLKKHLFSYQGHVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAESICSGIFNDLGSGSNVDICVITKGNKEYLRNYMEPNPRTYVSSKGYSFTKKTEVLLTKITPLLERVEITEVGEAMEE
Protein: Methionine aminopeptidase 1D, chloroplastic/mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Peptidase M 1D) (Q9FV50)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Subcellular location: Plastid, chloroplast {ECO:0000255|HAMAP-Rule:MF_03174, ECO:0000269|PubMed:11060042}. Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03174, ECO:0000269|PubMed:11060042}.
Interaction partners:
- Methionine aminopeptidase 2A
- Peptide deformylase 1B, chloroplastic/mitochondrial
- Peptide deformylase 1A, chloroplastic/mitochondrial
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein uL18z
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL30y
- 60S ribosomal export protein NMD3
- Large ribosomal subunit protein uL24c
Sequence:
MAGVKSLQPRLISSFLGNNSIRSTQPLIHLFRFDLGRRHVSMQLSRTFSGLTDLLFNRRNEDEVIDGKRKRLRPGNVSPRRPVPGHITKPPYVDSLQAPGISSGLEVHDKKGIECMRASGILAARVRDYAGTLVKPGVTTDEIDEAVHNMIIENGAYPSPLGYGGFPKSVCTSVNECICHGIPDSRPLEDGDIINIDVTVYLNGYHGDTSATFFCGNVDEKAKKLVEVTKESLDKAISICGPGVEYKKIGKVIHDLADKHKYGVVRQFVGHGVGSVFHADPVVLHFRNNEAGRMVLNQTFTIEPMLTIGSRNPIMWDDNWTVVTEDASLSAQFEHTILITKDGAEILTKC
Protein: Polysaccharide biosynthesis domain-containing protein (Q9XWK2)
Organism: Caenorhabditis elegans
Interaction partners:
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
Sequence:
MTDYGDADKYVNDESIEMAWAIKAGERSEVHMNLIMRCDTRVLRLNKHQDAILAAFRSSFPDLNVEEVTTSLLKDGGAKETWREFCEQFKDIVDDYSMGTLMRIHASKAYSPENTVVVPRIIYLAIEMARNVEGVNEKNKEAYTAHRNSLASL
Protein: Thrombin-like enzyme elegaxobin-1 (SVTLE) (EC 3.4.21.-) (Elegaxobin I) (Fibrinogen-clotting enzyme) (Snake venom serine protease) (SVSP) (P84788)
Organism: Protobothrops elegans (Elegant pitviper) (Trimeresurus elegans)
Function: Thrombin-like snake venom serine protease that clots rabbit fibrinogen. Only the beta chain of fibrinogen (FGB) is cleaved, releasing fibrinopeptide B. Incubation with human fibrinogen alpha and beta resulted in cleavage of both fibrinogen chains but generated neither fibrinopeptide A nor fibrinopeptide B. Promotes clotting of rabbit fibrinogen, but not bovine or human fibrinogen.
Subcellular location: Secreted {ECO:0000269|PubMed:10708800, ECO:0000269|PubMed:12076650}.
Interaction partners:
Sequence:
VIGGDECNINEHPFLVLVYYDDYQCGGTLINEEWVLTAAHCNGKNMEIYLGVHSKKVPNKDVQRRVPKEKFFCDSSKTYTKWNKDIMLIRLDRPVRKSAHIAPLSLPSSPPSVGSVCRVMGWGTITSPQETYPDVPHCAKINLLDYSECRAAYPGLPPKSRTLCAGVLEGGKDTCGGDSGGPLICNGQFQGIVSWGGDPCAQPHEPGSYTNVFDHLDWIKGIIAGNTDATCPL
Protein: Colicin I receptor (P17315)
Organism: Escherichia coli (strain K12)
Function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB.
Subcellular location: Cell outer membrane {ECO:0000255|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU01360}.
Interaction partners:
- Hydroxamate siderophore receptor FhuE
- Isochorismate synthase EntC
- Ferrienterobactin receptor
- Biopolymer transport protein ExbB
- Enterobactin synthase component B
- Iron
- Protein TonB
- Biopolymer transport protein ExbD
- Ferric enterobactin transport ATP-binding protein FepC
- Catecholate siderophore receptor Fiu
Sequence:
MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLILVDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNSTTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQNYSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGKYTLPLTAINQFLTVGGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGEHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFETGANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLSDLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF
Protein: Toll-like receptor 1-like protein b (A5H0S2)
Organism: Gallus gallus (Chicken)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MTKNMRYLRNCFIYNCLFVFTFWDNIGLAKKNELFASVPNNFPEDGLDKKNMSFPHSYANNQHYKADYGWVMIENTTESLSLSEIADDNVRKLITLLSKFRKGSRLRNLTLTNMSVDWKDIIKVLQVVWHSSIEYFNINNLTQLGNVVSTRFDYSKTSMKAFAVNKVLITDLYFSQDDVYNIFANMNIAALTIAESELIHMLCPSSDSPLRYINFSKNDLTDLLFQNCDKLIQLETFILHRNKFESLPKVSFMTSRMKSLRYLDMSSNLLRNSRAEGRCQWADSLAELDLSSNQLTEAVFECLPANINKVDLQNNQIASVPKGITELHSLQELNLASNRLADLPGCRAFTGLEILNIERNLILTPSADFFETCPSVKELQAGQNPFKCSCELQDFLRLERQSGGKLSGWPEAYVCKYPEDLSGTQLKDFHLTELACNTTLLLVTALLLTLVLVAVVAFLCIYLDVPWYVRMLWQWTQTKRRAWHDCPEERETALQFHAFISYSERDSLWVKNELIPNLEKGEGCIQLCQHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHKLFSENSNSLILILLEPIPPYVIPARYHKLKALMAKRTYLEWPKERSKHALFWANLRAAISINLSVADEQNRTEV
Protein: Uncharacterized protein (A0Q7H8)
Organism: Francisella tularensis subsp. novicida (strain U112)
Interaction partners:
Sequence:
MSQIISTLNNIDLVTQDKVNLISNMQIQAKYENAEYKSFIDQLIDNLNTTKSIDIYNLFLSLNSEICLNLDTVDNISKIISSYLSILNTNFTRISPSESKQKNQLAEKGINKFLVTMDANFAQMQNQEKLLPNNIDSIIEIVQEVIIFFEKNNLNYNSDFKIQLNKTLRKIKSSLILKDQKNDTYSDKEAINQVEASITDQKNIQGSEKWKTLIEKIEVLKALVESERIFETSIVYNDIQNLLVNFDPKEYFPEIFFPLYKKIAPFIGNIHKNIDYYSSSIQWSIAQKMYNIDYKSFLDTLERMPENNFLNSSSDITKNFFYETSSEVEKTPIEEHKIIADTDAIKEEIVIKQRTNNKKNQNDSVEKISNEIDEDYFEDLFDI
Protein: Putative P4-specific DNA primase (EC 2.7.7.-) (EC 3.6.4.12) (P10277)
Organism: Enterobacteria phage P4 (Bacteriophage P4)
Function: This protein acts as a DNA primase generating di- to pentaribonucleotides; the predominant product being the dimer pppApG. It complexes specifically to the P4 origin of replication (ori) and its cis replication region (crr). It also acts as a DNA helicase.
Interaction partners:
Sequence:
MKMNVTATVSHALGHWPRILPALGIQVLKNRHQPCPVCGGSDRFRFDDREGRGTWYCNQCGAGDGLKLVEKVFGVSPSDAAAKVAAVTGSLPPADPAVTTAAVDETDAARKNAAALAQTLMAKTRTGTGNAYLTRKGFPGRECRMLTGTHRAGGVSWRAGDLVVPLYDDSGELVNLQLISADGRKRTLKGGQVRGTCHTLEGQNQAGKRLWIAEGYATALTVHHLTGETVMVALSSVNLLSLASLARQKHPACQIVLAADRDLSGDGQKKAAAAADACEGVVALPPVFGDWNDAFTQYGGEATRKAIYDAIRPPAESPFDTMSEAEFSAMSTSEKAMRIYEHYGEALAVDANGQLLSRYENGVWKVLPPQDFARDVAGLFQRLRAPFSSGKVASVVDTLKLIIPQQEAPSRRLIGFRNGVLDTQNGTFHPHSPSHWMRTLCDVDFTPPVDGETLETHAPAFWRWLDRAAGGRAEKRDVILAALFMVLANRYDWQLFLEVTGPGGSGKSIMAEIATLLAGEDNATSATIETLESPRERAALTGFSLIRLPDQEKWSGDGAGLKAITGGDAVSVDPKYRDAYSTHIPAVILAVNNNPMRFTDRSGGVSRRRVIIHFPEQIAPQERDPQLKDKITRELAVIVRHLMQKFSDPMLARSLLQSQQNSDEALNIKRDADPTFDFIGYLETLPQTSGMYMGNASIIPRNYRKYLYHAYLAYMEANGYRNVLSLKMFGLGLPVMLKEYGLNYEKRHTKQGIQTNLTLKEESYGDWLPKCDDPTTA
Protein: ISDra2 transposase TnpA (TnpA-Dra2) (Transposase for insertion sequence element IS200/IS605) (Q7DF83)
Organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
Function: A transposase that is part of insertion sequence (IS) element ISDra2, it is necessary and sufficient for both transposon excision and insertion of ISDra2. This protein alone can be provided in trans and allows transposition of an empty IS element (tnpA or tnpA-tnpB replaced by a selectable marker). ISDra2 binds subterminal imperfect palindromes at the left (LE) and right (RE) ends of the element and cleaves only the 'top strand' which is circularized and subsequently reinserted into the DNA target. This is called a 'peel and paste' mechanism and increases the copy number of the IS (Probable). Transposition is linked to DNA replication in the absence of irradiation, with maximal activity when the 'top strand' is on the replication lagging strand, and occurs preferentially on the lagging strand. The IS element inserts 3' of the target sequence 5'-TTGAT-3'; target duplication has not been observed.
Interaction partners:
- RNA-guided DNA endonuclease TnpB
- Transposase, putative
Sequence:
MTYVILPLEMKKGRGYVYQLEYHLIWCVKYRHQVLVGEVADGLKDILRDIAAQNGLEVITMEVMPDHVHLLLSATPQQAIPDFVKALKGASARRMFVAYPQLKEKLWGGNLWNPSYCILTVSENTRAQIQKYIESQHDKE
Protein: Uncharacterized protein (Q57U93)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAALVEDMESLRKRLQLSEEWNLRLQSQIQELLQLPHNEVETLRSRMYNPDIAIPLLQCYDATILEKQDENEKLQQENHRLRSRLQEMTTNVAEMQEAVQTAEDLMKEKEVESQRQQRCIDDVRLQAEHECAKARQDLSRALETEGNMKREVKQMQRQLAAAQEEVVQRQREVATLEETLRLTQSRLKLASSEKEETQQQHEVQRIQLQLLSKENEDKMQELERLRSRMVQSLRQAAENHAAHMRIVEEKHREALEGLRMQLTTQELETQKLRAQLARVDTSGGGSKYEIATRTTTELLESQARQAQEIELKRLYAELSAVQIQRDDAQLRYEQLSSNLRREEAERTSEMQRGMQQLRSKLRELEQQHEQLEKEHARVKEEVRVLREKSKSHAGDLQRARQERDQSTKRAEELRRALSSAEEACETAKREGKEGVARERQRMEEQSRRSEEVLRELQMSKERTVAAMNAVELQRDDERHKLVAANERLEALQLRLDARERETEVLNSKLSHMQEAVRLNQQQAVACDERVQQLLAQDEEKSKQLRELKLLVERLKLESARATRAHDRLLEEVNVRLH
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (F7BN18)
Organism: Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Interaction partners:
Sequence:
MLEGGEGKKKCRRQQKGAGASCMQHMKMLEICLKLVGCKSKKGLSSSSSCYLEEALQRPTVSDIEPQGLSEAARWNSKENLLSGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSPEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSDSRFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPTIYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKEDTMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRECWQWSPLDRPSFAEIHQDFETMFQESSISDEVEKELGKKGLKVTVSNLLQAPELPTKTRITRRVPESKDENAETASVRAAGELDVFEPESAVSPLLPRKERGAGDGVLPDDDRLLPKDKKTNLFFSTLIKRKKKNAPTPPKRSSSFRDMEGHSERRSTDGEGKEANGGDLLDTFKLSTNGTALSNGSIQGSTGFLSSQWKKSSTMTGRQASPSEEETICSTSKRFLRSCSASCMPHGAKDTEWKSVTLPREITSSRCLLDTPGSDSLKKAEKPALPRKRGNESKPEGTRGTVTPPPRLPKKCEDPNDEVFKDADPSPNSSPPSLTPKLLRRKPAGPAGAPLQKEEASNIRLGSVNSDTGPSTKQTSFAGKSEAELRLRRPKTSEPATKDKVKVLKVKPSPPLPLSSIGSSPSASSNLGKAAKPPSQSHDTSPSEPKHKLTSQTDELSKTPPPVPDSSKKPVLLSSSKPQVTGKLSGGMVAGGDQSQPSAPSSSSSTAFVPLISTRVSLRKTRQPPEKHSSPVTKETVMASTECLKAAIARNSEQMASHSTVLEAAKNLHAFCTSYVDSIQQMRNKFAFREAISKLENSLRDLQICPAPAAAGGGAATSQDFSKLLTSVKEISDVVQR
Protein: Homeobox protein ceh-2 (G5ECT8)
Organism: Caenorhabditis elegans
Function: Required for activity of the M3 pharyngeal motor neuron.
Subcellular location: Nucleus {ECO:0000255|RuleBase:RU000682, ECO:0000269|PubMed:12810585}.
Interaction partners:
- Serpentine Receptor, class H
- Glycine rich superfamily member
- C-factor
- Aminopeptidase N-like N-terminal domain-containing protein
- Cadherin-3
- Biopterin-dependent aromatic amino acid hydroxylase family profile domain-containing protein
Sequence:
MTLKFSVERLVDSEKESEEADVEEQNNLKKLEEDEEDDELCEKSGKNEPLSQTLSYFDVLLPHVQMACSNPFISGIGASGSGDQNLNTGAGGSVWQHPWLELLQSTTAAQFGDVTAGLFLQPLRKNKRIRTAFSASQLIQLEKAFEGNHYVVGNERKQLAAKLSLTETQVKVWFQNRRTKHKRVRLEGSDPNAPMSNDEDDEDDKKSVS
Protein: Succinate dehydrogenase cytochrome B subunit, mitochondrial (O74882)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Probable succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- Fumarate hydratase, mitochondrial
- WW domain-containing protein C2F3.14c
- Fumarate reductase
- NADH-ubiquinone oxidoreductase 24 kDa subunit homolog C11E3.12, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
Sequence:
MFATRSFCLSSSLFRPAAQLLRPAGRSTLRNVWRRSIATEHLTQTEANSRLASQRVHRPNSPHLTIYEPQLTWYLSSLHRITGCVVAGTLYAFAMGYLVAPLAGYSLDTATISGLIQQVPTWIKVPAKFVISYPLTFHIFNGIRHLIWDTTKELSLKGVYRTGYAVLALSVLTSGYFAMI
Protein: Probable disease resistance protein At5g47250 (Q9LVT4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable disease resistance protein.
Interaction partners:
- Lysine-specific demethylase JMJ29
- Disease resistance protein
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- RNA polymerase I specific transcription initiation factor RRN3 protein
- RNA polymerase I specific transcription initiation factor RRN3 protein
- Glycosyltransferase family protein 2
- AT5g12260/MXC9_22
- RNA polymerase I specific transcription initiation factor RRN3 family protein
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
Sequence:
MNCCWQVVEPCYKSALSYLCVKVGNICMLKENLVLLKSAFDELKAEKEDVVNRVNAGELKGGQRLAIVATWLSQVEIIEENTKQLMDVASARDASSQNASAVRRRLSTSGCWFSTCNLGEKVFKKLTEVKSLSGKDFQEVTEQPPPPVVEVRLCQQTVGLDTTLEKTWESLRKDENRMLGIFGMGGVGKTTLLTLINNKFVEVSDDYDVVIWVESSKDADVGKIQDAIGERLHICDNNWSTYSRGKKASEISRVLRDMKPRFVLLLDDLWEDVSLTAIGIPVLGKKYKVVFTTRSKDVCSVMRANEDIEVQCLSENDAWDLFDMKVHCDGLNEISDIAKKIVAKCCGLPLALEVIRKTMASKSTVIQWRRALDTLESYRSEMKGTEKGIFQVLKLSYDYLKTKNAKCFLYCALFPKAYYIKQDELVEYWIGEGFIDEKDGRERAKDRGYEIIDNLVGAGLLLESNKKVYMHDMIRDMALWIVSEFRDGERYVVKTDAGLSQLPDVTDWTTVTKMSLFNNEIKNIPDDPEFPDQTNLVTLFLQNNRLVDIVGKFFLVMSTLVVLDLSWNFQITELPKGISALVSLRLLNLSGTSIKHLPEGLGVLSKLIHLNLESTSNLRSVGLISELQKLQVLRFYGSAAALDCCLLKILEQLKGLQLLTVTVNNDSVLEEFLGSTRLAGMTQGIYLEGLKVSFAAIGTLSSLHKLEMVNCDITESGTEWEGKRRDQYSPSTSSSEITPSNPWFKDLSAVVINSCIHLKDLTWLMYAANLESLSVESSPKMTELINKEKAQGVGVDPFQELQVLRLHYLKELGSIYGSQVSFPKLKLNKVDIENCPNLHQRPL
Protein: Early E1A protein (Q8JSK4)
Organism: Human adenovirus B serotype 3 (HAdV-3) (Human adenovirus 3)
Interaction partners:
Sequence:
MRHLRFLPQEVISSETGIEILEFVVNTLMGDDPEPPVQPFDPPTLHDLYDLEIDGPEDPNEEAVNGFFTDSMLLAADEGLDINPPPETLVTPGVVVESGIGGKKLPDLGAAEMDLRCYEEGFPPSDDEDGETEQSIHTAVNEGVKAASDVFKLDCPELPGHGCKSCEFHRNNTGMKELLCSLCYMRMHCHFIYSPVSDDESPSPDSTTSPPEIQAPAPANVCKPIPVKPKPGKRPAVDKLEDLLEGGDGPLDLSTRKLPRQ
Protein: GST-containing FLYWCH zinc-finger protein (GST-containing FLYWCH zinc-finger protein, isoform E (EC 2.5.1.18)) (LD30165p) (Q6NP69)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Hmr
- LD09786p
- Glutathione S transferase O1
- Glutathione S-transferase S1
- Glutathione S transferase T1
- glutathione transferase
Sequence:
METPVEEHGMDLTKVSVVRSAKGVDMLCVDDYLYHFDRIGRNNTYRWLCNRRKDKSTPCKSRICTMLPDPLDKTRHVVVDVVLAHIHPRCSDHEVNKVAQRKRLSVMMMNDAYSTTQPKRARLYERANAGMNPPEFIYGSIDTSTVEASFQLDFEDKDRVYMLRRRDGRVMVCIDGHLYYLAGKSYKGDIFRWTCVRKRDIECTARICTEATLAGAHRLHAVDTDAHIHPHYSAAKLMHMFSKHQIVLVEDENTSDVLAECPNLEYFDPENTFDTAQRGDDLESIIIEECEDNYDIYMRTDGSQGGGIQGSEELESQEGDDESSLVDPKMHHSSKWPAAFDVIANYLPPPSHNPLTETDLTKFTFLPSAKGRKVLCLSQHLFHFDSQSRSNGHMFFTCINRRDKANTCHVRITLDPVENGPVVLRINGEHTHNPDIKEIARRLKQQAKLDQDNVHKLQKIEHSEEISFESDEGSASQGGDTFEAENSVDESYGHIDTRNVVMKKVISIDGAIKMEPESKANMIVQYLKDGANNISAKIEILPDALDELDPHSHTAYSSTPLPKVRQPQITNIRRRRDVAEPAKGAQPDMDLSKICTLRSAKGHELLCVDGYIYHAKNRGVISRNYWVCIKSRDPDINCKSRISTATQKDGSIRVLRVYNSHSHPFSEDDIKRRLYNEINKKNNKNLKFRPLHFIGKSLDQIQQEYGDLAIERLNVSNISSDIVVHKKPRVSGSNNSRSASLSVSHRADSHHEEDDVVIVEEEYQEQEEGVEMTMEGDQQYMDVDNTDGIIEVVEEVADEMESYGSIVPIYTMKLYAVSDGPPSLAVRMTLKALDIQYQLINVDFCAMEHRSEEYSKMNPQKEIPVLDDDGFYLSESIAIMQYLCDKYAPDSTLYPQDVNVRAVINQRLCFNMGFYYAPISAHSMAPIFFDYKRTPMSLKKVQNALDVFETYLQRLGTKYAAGENITIADFALISATICLEAINFDLHQFTLVNKWYETFKVEYPQLWEIANSGMQEISAFEQNPPDMSHMEHPFHPTRKSMGLKL
Protein: Calmodulin-binding protein 25 (AtCAMBP25) (VQ motif-containing protein 15) (AtVQ15) (O80683)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Calmodulin-binding protein that functions as a negative regulator of osmotic stress tolerance.
Subcellular location: Nucleus {ECO:0000269|PubMed:15086802}.
Interaction partners:
- VQ motif-containing protein 22
- VQ motif-containing protein 29
- VQ motif-containing protein 9
- Sigma factor binding protein 2, chloroplastic
- Sigma factor binding protein 1, chloroplastic
- Protein HAIKU1
- VQ motif-containing protein 17
- VQ motif-containing protein 8, chloroplastic
- VQ motif-containing protein 18
- Protein MKS1
Sequence:
MVTSEGLASVDSWLYRQGFNVDSWLLSDTFSHDNDLLARALHTTVTAPHTLTPSSAFFDSSAVSHPSSTNTLSSTVSGASDPEIIGGGAKRKRNCLLTDGKAAKRRARASKKSQTTFITADPSNFRQMVQQVTGAKYIDDSSSFGIFDPIVKPEPLRFVNKLPCGPSDRSTAVPMLDTSAFLSNHHQENLAVGNAFSGNSSSVGLPSGKPSATADPGGSAVEFDNYPTFPTLESWKVM
Protein: Aminopeptidase O (AP-O) (EC 3.4.11.-) (Q8N6M6)
Organism: Homo sapiens (Human)
Function: Aminopeptidase which catalyzes the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q8BXQ6}.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm {ECO:0000250|UniProtKB:Q8BXQ6}.
Interaction partners:
- Angiotensinogen
- DENN domain-containing protein 1A
Sequence:
MDIQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIVLFLEDGNRFKKQNSSIEEACQSESNKACKFGMPEPCHIPVTNARTFSSEMEYNDFAICSKGEKDTSDKDGNHDNQEHASGISSSKYCCDTGNHGSEDFLLVLDCCDLSVLKVEEVDVAAVPGLEKFTRSPELTVVSEEFRNQIVRELVTLPANRWREQLDYYARCSQAPGCGELLFDTDTWSLQIRKTGAQTATDFPHAIRIWYKTKPEGRSVTWTSDQSGRPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLATERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFAPVCLTGACQETLLRLIPPCLSAAHSVLGAHPFSRLDVLIVPANFPSLGMASPHIMFLSQSILTGGNHLCGTRLCHEIAHAWFGLAIGARDWTEEWLSEGFATHLEDVFWATAQQLAPYEAREQQELRACLRWRRLQDEMQCSPEEMQVLRPSKDKTGHTSDSGASVIKHGLNPEKIFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEMLF
Protein: Ras-related protein Rab7 (DRab7) (EC 3.6.5.2) (Small monomeric GTPase Rab7) (Small ras-like GTPase) (O76742)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:24327558}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Late endosome membrane {ECO:0000269|PubMed:11136982, ECO:0000269|PubMed:23418349, ECO:0000269|PubMed:24327558}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Lysosome membrane {ECO:0000269|PubMed:24327558}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:27559127, ECO:0000269|PubMed:28483915}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Autolysosome membrane {ECO:0000269|PubMed:28483915}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Presynapse {ECO:0000269|PubMed:24327558, ECO:0000269|PubMed:32658990}. Perikaryon {ECO:0000269|PubMed:24327558}. Note=Partially colocalizes with the early endosomal marker Rab5 and the lysosomal marker spin/spinster (PubMed:24327558). Recruited to endosomal and autophagosomal membranes in a Mon1-Ccz1 guanyl-nucleotide exchange factor complex-dependent mechanism (PubMed:23418349, PubMed:27559127). Recruitment to endosomes is not reliant on phosphatidylinositol 3-phosphate (PtdIns[3]P) enrichment (PubMed:23418349). Colocalizes to autolysosomes with active GTP-bound Rab2 (PubMed:28483915). {ECO:0000269|PubMed:23418349, ECO:0000269|PubMed:24327558, ECO:0000269|PubMed:27559127, ECO:0000269|PubMed:28483915}.
Interaction partners:
- Vacuolar protein sorting-associated protein 39 homolog
- Vacuolar protein sorting-associated protein 41 homolog
- Vacuolar protein sorting-associated protein 16 homolog
- Vacuolar protein sorting-associated protein 18 homolog
- Vacuolar protein sorting-associated protein 11 homolog
- Rab GDP dissociation inhibitor
- Vacuolar fusion protein MON1 homolog
- Vacuolar fusion protein CCZ1 homolog
- TBC1 domain family member 15
- Vacuolar protein sorting 33B
Sequence:
MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC
Protein: Cationic amino acid transporter 2 (CAT-2) (CAT2) (20.5) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) (T-cell early activation protein) (TEA) (P18581)
Organism: Mus musculus (Mouse)
Function: Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. May play a role in classical or alternative activation of macrophages via its role in arginine transport.
Subcellular location: Cell membrane {ECO:0000269|PubMed:8195186, ECO:0000269|PubMed:8385111}; Multi-pass membrane protein {ECO:0000269|PubMed:8195186, ECO:0000269|PubMed:8385111}.
Interaction partners:
Sequence:
MIPCRAVLTFARCLIRRKIVTLDSLEDSKLCRCLTTVDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVRWSPAKYVVSAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATMTAGVISAVMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYDQPKYTPEKETLESCTNATLKSESQVTMLQGQGFSLRTLFSPSALPTRQSASLVSFLVGFLAFLILGLSILTTYGVQAIARLEAWSLALLALFLVLCVAVILTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWIRFSIWMALGFLIYFAYGIRHSLEGNPRDEEDDEDAFSDNINAATEEKSAMQANDHHQRNLSLPFILHEKTSEC