wanglab/gogpt-training-data huggingface dataset:
Protein: Olfactory receptor 1E2 (Olfactory receptor 17-93/17-135/17-136) (OR17-135) (OR17-136) (OR17-93) (Olfactory receptor 1E4) (P47887)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILKVPSSKGICKAFSTCGSHLSVVSLFYGTVIGLYLCPSANSSTLKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL
Protein: Peptidyl-prolyl cis-trans isomerase FKBP16-1, chloroplastic (PPIase FKBP16-1) (EC 5.2.1.8) (FK506-binding protein 16-1) (AtFKBP16-1) (Immunophilin FKBP16-1) (Rotamase) (Q944B0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular location: Plastid, chloroplast thylakoid lumen {ECO:0000250}.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase FKBP13, chloroplastic
- Photosynthetic NDH subunit of lumenal location 4, chloroplastic
- Peptidyl-prolyl cis-trans isomerase FKBP20-2, chloroplastic
- Protein INCREASED PETAL GROWTH ANISOTROPY 1
- Photosystem I reaction center subunit XI, chloroplastic
- Peptidyl-prolyl cis-trans isomerase FKBP16-3, chloroplastic
- Photosynthetic NDH subunit of lumenal location 5, chloroplastic
- Peptidyl-prolyl cis-trans isomerase FKBP15-1
- Peptidyl-prolyl cis-trans isomerase CYP38, chloroplastic
- Peptidyl-prolyl cis-trans isomerase CYP20-3, chloroplastic
Sequence:
MAMAMEISLPFVGSSMALSAGKSRNSVSRISRVGFSSVSAVHVPRRMFMQLSGFGSVLTLLDFPSLAAPVPQMKEPEVIRTLKLPSGVRYQEIIEGEGREAHEGDLVELNYVCRRANGYFVHSTVDQFSGESSPVKLILDENDVIEGLKEVLVGMKAGGKRRALIPPSVGYINETLKPIPEEFGPRRSLLSHANEPLVFEIQLLKVL
Protein: Insulin-like growth factor 3.L (Insulin-like growth factor 3) (xIGF-3) (Insulin-like growth factor III) (IGF-III) (Q90WX8)
Organism: Xenopus laevis (African clawed frog)
Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Promotes anterior neural development.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MPVTAMCLQDSKKLKKAKLTRKKVTPFPFSRMVLCLSLVFTLYVEATNARCLRPRSKELLCGSELVDILQFICGPTGFYVSKGASFRNRNRPGIVEECCFCGCSVAILESYCAAPVTNFTGREEQKS
Protein: PH-sensitive chloride channel 1, isoform G (E1JI08)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTETQTEVAAVVAIATDAGAETETETEAEAQKEPATGPEHLKAAAQVLLTIRQARQENNKHSSSQVAETHKDEGEDALARQGSIVDTAAGRIGIDIAATTIQVAERHEDGQHWQQHNVRRRRRQPDPAAHPASITKLSAISLHFHALAALAKTLQKHEDLSPVQDRQPLAYRAWQEHPYAETQMPATMSAAIIANVGATAAATSAAAFQYLGQHYKHYSQSISFYAASSVLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALHHHDSIWTPDTYFIMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLRVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARSMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQPVSMP
Protein: Heat shock protein 40, type II (Q8I489)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Heat shock 70 kDa protein
- Heat shock 70 kDa protein
- Endoplasmic reticulum chaperone GRP170
- Heat shock protein 110
- Heat shock protein 70
- Endoplasmic reticulum chaperone BIP
- HSP40, subfamily A
- Heat shock protein 90
- Heat shock protein 90, putative
- Endoplasmin, putative
Sequence:
MSILNKYEGKKNKIFLFIINIILFYTLEYVLIGSNYDKHNQSFGNEIFKNTKVFDFTSLRSLAEFNSGSSRESSKTDETDYYAVLGLTKDCTQDDIKKAYRKLAMKWHPDKHLNDEDKVEAERKFKLIGEAYEVLSDEEKRKNYDLFGQSGLGGTTTNDEAYYTYSNIDPNELFSRFFSHDASSFFSQGFDDFPSFQGFASMNSRRPRSSRSNIFSRSFGRAASFEVPLQVTLEELYTGCRKKLKVTRKRFVGLNSYEDNTFITVDVKPGWSEGTKINFHGEGEQSSPNEQPGDLVFIIKTKPHDRFIREGNNLIYKCYLPLDKALTGFQFSIKSLDNRDINVRVDDIINPNSKKIITNEGMPYSKSPSVKGDLFIEFDIVFPKKLSPEQKRTLKETLENTY
Protein: RNA-binding protein 12B (RNA-binding motif protein 12B) (Q8IXT5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHLFDSKDPPIYSVGAFENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLPDNFRPPGEDFRSPPDDFRSHRPFVNFGRPEGGKFDFGKHNMGSFPEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDLNDRPVGPRKVKLTLL
Protein: Fructose-bisphosphate aldolase B (EC 4.1.2.13) (Liver-type aldolase) (P05062)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:35122041}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:18000879}.
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase
- ATP-dependent 6-phosphofructokinase, liver type
- Triosephosphate isomerase
- ATP-dependent 6-phosphofructokinase, muscle type
- ATP-dependent 6-phosphofructokinase, platelet type
- Fructose-1,6-bisphosphatase 1
- Fructose-bisphosphate aldolase A
- Fructose-1,6-bisphosphatase isozyme 2
- Ketohexokinase
- Pyruvate kinase PKLR
Sequence:
MAHRFPALTQEQKKELSEIAQSIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFREILFSVDSSINQSIGGVILFHETLYQKDSQGKLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYASICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAANKEATQEAFMKRAMANCQAAKGQYVHTGSSGAASTQSLFTACYTY
Protein: Dynein axonemal assembly factor 4 (Dyslexia susceptibility 1 candidate gene 1 protein) (Q8WXU2)
Organism: Homo sapiens (Human)
Function: Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.
Subcellular location: Nucleus {ECO:0000269|PubMed:12954984, ECO:0000269|PubMed:16989952}. Cytoplasm {ECO:0000269|PubMed:12954984, ECO:0000269|PubMed:16989952, ECO:0000269|PubMed:23872636}. Dynein axonemal particle {ECO:0000305|PubMed:23872636}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q5VJS5}.
Interaction partners:
- Doublecortin domain-containing protein 2
- Dyslexia-associated protein KIAA0319
- Dynein axonemal assembly factor 6
- Dynein axonemal assembly factor 3
- Protein kintoun
- Dynein axonemal assembly factor 1
- Roundabout homolog 1
- Dynein axonemal assembly factor 11
- Cilia- and flagella-associated protein 298
- Zinc finger MYND domain-containing protein 10
Sequence:
MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
Protein: Transcription factor IBH1-like 1 (AtIBL1) (BHLH transcription factor eta) (bHLH eta) (Basic helix-loop-helix protein 159) (AtbHLH159) (bHLH 159) (bHLH transcription factor bHLH159) (Q9M0B9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions redundandly with IBH1/BHLH158 in a regulation node known as the incoherent feed-forward loop (FFL). Acts as transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor IBH1
- RING/FYVE/PHD zinc finger superfamily protein
- Protection of telomeres protein 1c
Sequence:
MQPTSSMNEEFLKKWQMGLQIFRPSIDNTSVHERKKAIKLSADVAMASLRKGTTCWSRALIEKTATEDNFLVRQMLSGIKAETLINKKLPKKTVCHRKIVRRSKKILRRKSKSASEEAAAKAKRLVKRRTQGLRNVVPGGELMSNDVLLLQETLDYIVSLQTQVNVMRSIVDAAEAEIER
Protein: Transaldolase (EC 2.2.1.2) (O42700)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Interaction partners:
- Probable transketolase
- Glucose-6-phosphate isomerase
- Triosephosphate isomerase
- Fructose-1,6-bisphosphatase
- ATP-dependent 6-phosphofructokinase
- Probable phosphoketolase
- 6-phosphogluconate dehydrogenase, decarboxylating
- Ribulose-phosphate 3-epimerase
- Fructose-bisphosphate aldolase
- Glyceraldehyde-3-phosphate dehydrogenase 1
Sequence:
MSSLEQLKATGTVVVSDTGDFESIAKYKPQDATTNPSLILAASKKPQYAALVDAAVDYAKAKGGSINSQIEIAFDRLLIEFGTKILAIVPGRVSTEVDARYSFDTQTTIEKARHLIKLYEAEGIGRERVLIKIASTYEGIQAAKQLEEEGIHCNLTLLFSFVQAVACAEANVTLISPFVGRILDFYKAKNNRDYTAQEDPGVVSVSNIFNYYKKFGYKTIVMGASFRNVGEIKELAGVDFLTISPALLEQLNNSTDAVPKKLDASKASSLNLEKVSYLTDEPKFRFDFNNDEMAVVKLSTGIAAFAKDADTLRTILKAKLEA
Protein: Calponin-homology (CH) domain-containing protein (O17666)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Spindle apparatus protein lin-5
- Kinesin motor domain-containing protein
- Kinesin-like protein
- Kinesin-like protein
- Kinetochore protein Nuf2 homolog
- Calmodulin
- Kinesin-like protein klp-19
- Protein regulator of cytokinesis 1
- Kinetochore-associated protein rod-1
- Kinetochore protein ndc-80
Sequence:
MDNNVEDKKEAMLKRLANRHEKRLLDQVKSNTKKIDLRATERAFLESSPTSMNMRTPLNPSISSSVSDSPILSYDEKANKQIIALATWCNTMMELDVSEEMDLGESKAEACRNIQKMLKKRSDTSEVENTQENARRRYQRIFEKNDPEVVKKKCKQLLDDSGMDASIKDLLSKNNVAIRKEHAVYNDIGLQTTLLHTFLSFHPAWLKTALEAIFNTRIDAQPKHLMKKLSQFFLDLVFSNPTMLKNKKFAQGSGKPIITEAGKEALHKHFLSVSMKLMFLIETAHTHRVIPNLTRIFTKSSHFNCLDDVFSELTKELLTGSSATFKKAFAKVGFIPTYRQSFIENYDYQAKGFSDFSDGLILAKLLETVGEMPHGQILLKLRDPAGDRIRKIGNVKIVLQEMSSLGVPTDNVNAESIVGGKKDEILSILWAIIGVRVAKEQRIKVTRVSEERTPKKRRSAVHDDMSSEVLKMCKIYGRQMEIEVMDLDSLSDGCLLAKLWTTFGTNSTPIQDYDGLSLWEKVVSVAELELCIQRGLDQNMALFVKMFLERLGMIQDLNEKATKIQRMWKAYVQRKNTPKLYFIVQQLLADSSIPRNRSVSPFSNNVTFTVPRTPRNNILTERPSLSQIPSSRQSMDSTFNDATFTVSRDSIESMNKMQKTPLRGTFTRKTIAMVIEEEDDSENNETVVPSTLKKRTVVRMEHNAEVFREQDEDDENQDKDTVAPSAENLDSPPSDIPLETLSSIPSASQSAIFLQDSETGKEMHVPKAEDVGVVVLEASDSPVALEGNNEASYDGQKIENLETFEIKEGKTQEDLPSKSPMDPTQTSGSPLVEFRMTEEQERLEMLFQSLSEDQKNFVKTNNLSVSIEDDANTPELRRILRQTRELKRKQQEIARKLGNIERNALAVRDGGEDSSDSRSDAGHDVAILHGDDSQLFENSMQLDQKSQLQNDETQILENKKKAAVVIQKMIRGFIARRKFQMEISNIRNRMIQYNHILAQEDEQIGIEEMEDKSVEAKLKKCALHGLTNDNLHVVHVAATVIDRVTDLVPSLLEKLVVELNGIKSITDVLIVADRGFSYTSILHPLLNVLEKLFTKIPEEVTNSHILPHLKILSPRLMLLMLKHSEVKELFIPIINTLTSIARRFPDKKQSSFSSSSYSIKQSLKKVKDQECRNKLVRLESICEDML
Protein: Uncharacterized protein (Q5ARB0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MAQLWGWISVYCLLILSFTVRSLGQEQSAFCEHSSLARECWGQYNISTDYHAITPDTGVTREYWLVAENTTLAPDGYERQVLVFNGTLPGPLIEANWGDELVIHVTNGLEHNGTAIHWHGIWQRGTNQYDGVPGVTQCPISPGQTYTYRFRATQYGTTWYHSHFSLQLAEGLFGPLVIHGPASADYDVDLGSVFISDWYHKSAFILWEESTRYGGVPVRANAVPPTGLFNGSNVFGGGGRRSEMIVEKGKKYRLRLIDSSVDGWMKFSIDGHKLTVISADLVPIEPYETDAVILTSGQRYDVVFEANQKIGNYWTRVIYQTACNGLDIKDPDIRGILRYAGAEISDPTSSQWSSIRNSCGDEPYDKLVPYVKRTVGKAAGQENLNVGWYYDLPELYFHWTLNTKALTIDWGTPTNKLIYNNESVFPTEYNIYEVPNRDQWTYWVIQDVGLVNAYHPFHLHGHDFFILAQGRGLYTPLVKLNRDNPPRRDTATMAGNGFLVIAFESDNPGSWLMHCHIAWHASQSLALQFVERESEIGPLIEPVIGEIESDCKKWEKYHAESVYHQDDSGI
Protein: STOP axonemal protein (Q57YM5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTTLHTISSLDYGDGRTCVCRICVCGKHRCTDPKLPFFGETTYRDEYVPKSTVRDIGRARPSTVFPMKADPGHFKTTKQEAWEPLEGKIVRPAESFKPRTVLGEPLPFNATTTHRNDFPGHLPDHHRARYKQEPLPKLKGTYETTNQAMQEPLNKHLEAGEMPKPPQPFRGDATLLRSLPFDAMATYTVDYPPKEALQQPRPPQKQPFESMPDVRDFGTTHSESYKVPPHRVRRVCPASQLAPRPPSVDGHYKLSVYAIPSGEIAD
Protein: Pre-mRNA-processing factor 19 (EC 2.3.2.27) (PRP19/PSO4 homolog) (RING-type E3 ubiquitin transferase PRP19) (Q7KWK5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Probable ubiquitin-protein ligase mainly involved in pre-mRNA splicing and DNA repair. Core component of the Prp19 complex/PRP19C/Nineteen complex/NTC which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9UMS4}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9UMS4}.
Interaction partners:
- WD40 repeat-containing protein
- Cell division cycle 5-like protein
- Pre-mRNA-splicing factor SYF1
- Pre-mRNA-splicing factor spf27
- Intron-binding protein aquarius
- Crooked neck-like protein 1
- Pre-mRNA-splicing factor ISY1 homolog
- Pre-mRNA-splicing factor SYF2
- Small nuclear ribonucleoprotein E
- Splicing factor YJU2
Sequence:
MICAISGSTTEEPVISTKTGNVYEKRLIEKYIDTNGKEPTTGEPLGLSDLITVKIGKTVKPRPTTATSIPSMLQLFQNEWDSLMLETFTLKQQHETVRQELAHSMYQYDAACRVIARLVKERDAARSALANARNIVQQQQQQTNNNNNNNNNKDVEMSSASTPSSSEDNLLDSTIYKRIAEKSEELIKTRKERTHQSLAEPDAIKQFKVSANVETDCQIKSLEVNSQDNNLIAMGGINGNVYVYSRETNELCTAIKGTSSAPINKVLFAPNNTIVSAGSDAVIRVVKGGESPSKKTYTQYKSTYQFAHKASVTDISLHVLGDYIISSSLDKSLNMYDIVNGTHLTSFGQSQQLCYTSVAFHPDGMFFAAGTQNGVVKIFDLKSKVNSFNFQGLSTAVNCISFSENGYYLTAADNNTVKLFDLRKAATKNSPDIQTITLDNQQIKSINFDYSSQYLGVASSNQINLYSCKSKQKPPISSIHSIDSDCLDFKWARPNSNFFVTSSSSKNIVNIFSN
Protein: T. brucei spp.-specific protein (Q583G3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MICVVHHTPPAYHSSSVTLSCLTFPCFFVTLYPSRRSHMETRLFFFCFCFFLSLFVCWFIAPSLLSFAILLYALKLVSGKKKNEGKERKERGGHLKTTCVYLGKYIYLYMYVSRHAYTFIYQTHEMKEKEKKGNRSVEFVCLLVSFSFFKKKKSDLLNVRGCLHLSDCSITPVKGVLLRLG
Protein: Basal body-orientation factor 1 (Q385Y2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQSRVSPGSGRRNRLSTPEAPQRTNAVPSGDTVISTFANVDLRVAKAAMNDYARSCEVMARENEQLRLELQRQEEESIKVVEHLKEKLEEARNTVMEQQNEINRLQHEGNEATEAVRRQYTQMLGERDEQVAQYAALTQRLQTEMRACARSIHLREESRLEVQRLRDQIEEMTARHESELSALRFQTVDRKMRLLALEETMRESHQARVEHESSLLLEKKSHELLKNYRELQEERTRLVKDIDELMQLTTMKAAEFVDERRKGDLHQHACEEALRRIANSNKRSCEMQMKTQRLEQHVKELLQEKKSLREELSRQYEGKIQALEKALAETQSSLRCHRTELQRMRYAASKIVEQRSDLEKFFYVALNDVRKMRTKSSKNRGNTPHSTSHTSPSMSLHSNSTLKQCASFSSKLPQLSPPQKAQQAEPNLSSRNSAVLSASTGETRLQPHSPCVPAPPPPVQEVCASATSAAGKQARQERPAPLRRAHSNGIKPTQDAPVRGTVENVDSRLHINLGEDGKGVYLNDLSWDDKEKIIKALLFFINQTCYQPLSKTGGENVDEPEPVTAN
Protein: Akirin-2 (A0A287BDC1)
Organism: Sus scrofa (Pig)
Function: Molecular adapter that acts as a bridge between a variety of multiprotein complexes, and which is involved in embryonic development, immunity, myogenesis and brain development (By similarity). Plays a key role in nuclear protein degradation by promoting import of proteasomes into the nucleus: directly binds to fully assembled 20S proteasomes at one end and to nuclear import receptor IPO9 at the other end, bridging them together and mediating the import of pre-assembled proteasome complexes through the nuclear pore (By similarity). Involved in innate immunity by regulating the production of interleukin-6 (IL6) downstream of Toll-like receptor (TLR): acts by bridging the NF-kappa-B inhibitor NFKBIZ and the SWI/SNF complex, leading to promote induction of IL6 (By similarity). Also involved in adaptive immunity by promoting B-cell activation (By similarity). Involved in brain development: required for the survival and proliferation of cerebral cortical progenitor cells (By similarity). Involved in myogenesis: required for skeletal muscle formation and skeletal development, possibly by regulating expression of muscle differentiation factors.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:B1AXD8}. Cytoplasm {ECO:0000250|UniProtKB:B1AXD8}. Membrane {ECO:0000250|UniProtKB:B1AXD8}. Note=Present mainly in the nuclear fraction, and at much lower level in the cytoplasmic and membrane fractions. {ECO:0000250|UniProtKB:B1AXD8}.
Interaction partners:
Sequence:
MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPTSAAASPSSAAAATAASFSAAAASPQKYLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFLLSGPASPGTPSATSSPLKKEQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHDQIMRRYGEQPASYVS
Protein: Inward rectifier potassium channel 13 (Inwardly rectifying potassium channel 7.1) (Potassium inwardly rectifying channel subfamily J member 13) (Q0KIZ7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003822}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003822}.
Interaction partners:
- Gap junction protein
- Gap junction protein
- Neurogenic locus notch homolog protein 1
- Immunoglobulin superfamily member 11.
Sequence:
MPTTMTNTTADQKASCPLMVKPQRRRLVSKDGRSQTRGNTRGGSRETCFSALRDLWGTWLALRWRWVVLAFCGSFLLHWLLFAVLWYLLARVNGDLDVLDHDSPPPGHVLCVKHVNGFTAAFSFALETQLTIGYGTMYPNADCPTAIALLALQMLLGLMLEAFITGAFVAKFSRPQKRCDGILFSPQAVVCEQKGQRCLMFRVCNLQPQPLVDVSVSAVLYEERDDHELHQTALEFSIDNLGSRSCPLFLSPLTFFHPLNPSTPFINNPSSQTHFELVVFLTATQESTGSGYHKRTSYLPDEIQYGYCFSKVTSVHQNKTPNMRYFDTVPCPLTLANTHTTDTPDKEHVVVQLNGEGSDRVE
Protein: Centrosomal protein 250 (H7C0P0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
LEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVVLLQAQLTLERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQAPEATVLEAETRRLDESLTQSLTSPGPVLLHPSPSTTQAASR
Protein: Type II NADH:quinone oxidoreductase (EC 1.6.5.9) (NDH-2) (Q2FID4)
Organism: Staphylococcus aureus (strain USA300)
Function: Alternative, nonproton pumping NADH:quinone oxidoreductase that delivers electrons to the respiratory chain by oxidation of NADH and reduction of quinones, and contributes to the regeneration of NAD(+).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q2FZV7}.
Interaction partners:
Sequence:
MAQDRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEASAGTLNYEDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQGIYDFDILVVALGFVSETFGIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEKDDNDLSILVGGAGFTGVEFLGELTDRIPELCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHAVSYLEDRGVEFKIATPIVACNEKGFVVEVDGEKQQLNAGTSVWAAGVRGSKLMEESFEGVKRGRIVTKQDLTINGYDNIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIKRILNGESTEEFEYVDRGTVCSLGSHDGVGMVFGKPIAGKKAAFMKKVIDTRAVFKIGGIGLAFKKGKF
Protein: Cd69 molecule (A0A8I6G1Q9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004401}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
Interaction partners:
Sequence:
FHIPQKISTAQSYSLNSPHFFPFTDHGTSVHFEKHREGSIQVPIPCAVLVVVLITSLIIALFALSVGKYNCPGFYENLESFDHHAASCKNEWFSYNGKCYFFSTTTKTWALAQKSCSEDDATLAVIDSEKDMAFLKRYAGGLKHWIGLRNEASQTWKWANGKEFNSWFNVTGSKKCVSLNHTDVASVDCEANLHWICSKASL
Protein: Probable serine/threonine-protein kinase roco7 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 7) (Q55GE6)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- RhoGEF domain-containing protein
- DOCK family protein
Sequence:
MDGYSSLSSSGNSIAPPRPTNNSVGGGSNSNNYNQREITTPLRGMVPNLGDGSSSQTLLFKNILLLQDVEFFCSILDNFCRSSSTQKITDLINSLIVILDDSFLELLRLFIKQTIDQAKQCSTDESNPLNYQSFYNLINRMAAIYLKSQLGGLMEKTMISQVLNFTPMIQEQIVILANKEANKNNNNVLSANSTPNVTALKTSPAIGSPRIIMGSNYNNSSNNNNIDSIDLNNNSPNMLKNNSPSTFINGSVPQINGGGGSYNLTPISSPTIGSSTPTIITSSSSTTTPTNNNNSNNNTPIISQTIIQNINVEHMKDQISQFSISIINTIFRSIEKFPPTVFQLFEMLYLDIHQVFSPDFCFELMKKIFFTKLICPILANLKSPPNMANGKFFTKTYIEISKVVLDIAFDRDQSRRGSVTTQEQIMHFIKGMIFRNTHSISMTAALNPTLNNQVIPPSIPLPSKEEACNNFINNIRSESSELEESFKRAKDLNTCISFARADRQIYLFSIFKEMLINFKISFNLLNNNQNNNQNINQNNNNNNNQNCNSNTSSPIISSRSGFYTLRNSSTNSSPTNPPLTARGNGSISIGNNNNNNNNNNNNNNNNNNNNNNNNSGGGGGGLNNSSNLLINPWVSSYQNSNISNSDQVQSTRVVQSFSKKWTSDELRPTYLGKSPKKRSWVLDKKNIKTQIINLHIFLDNYSVCRIVTVPMNITFQALANRIHTDSEFSDIQLNKEEYEMVIRYPEESITVLNDEGNQEVICEPELPLWMFDIDTESIIIFRPIKRRSPSSSFNIFLKFIFPSNSSFNSSSSSLPSTPHQKINPMILYINPQSTPQSIIDKFSKLIQPSLLDTAHLGFYLRDIDDESSSPPSIKIPNNNSFAHNKISTMDIIECGPRLSYEFSITVNGTIQNILIDFDNQIDNVANIFYNIYQHLIELSPRSLSSSSSSSSDINNNNNNNTNNNIELTSSGRILTSNGSKHNSNNSNNSSGSSNISEQNLKRSSGIIDSIINGHSNNNSNNYALALLSNSNFLPMFLPGQSKLQDYCFNVGDELILTEKTFVQLVEVLATPRRPPIALSSSLSQSNAFNSNVYNSNAYNSNVYNSNPYLSNYNGLSSQSLNSMNVDGAGGVGGFNGEQNQQQNKVIARVRVIWAGSNSSVDRLQSFINTSQNVNTTYSGSTMALNDVLSNPNQLLSTPLSRPLLSTVIAQDNTYICTSKNDYCMNNQVKLCIVGEESQEKLSFYNSLRKNYSQNGLLSSGGGRGGGFFGSNFIPSSTSNVNEVSSIDGVLHTSELVVGSAEIDQITLKTFYISGNEQYQVVHPLFISPQSLFIITYNPMNINSTMINYWLEIIQTKAQGSTVYLVGLSNTSIDEKKFVSFKSEYHRLFRFNNINSYSNISLKNSKQIKQLVQRLQNNAMMKQYHYKIPLSYSILKSQCQESVKEAYARNKMPLSSIPLIKNIARIFSIEPRDSEAAIKYLYEIGEVLYYRYEANDQLLNELVFLDSMWMSKLISAVLALKTQNGMTVVDQITQAWASLFPHCKTSSLLFLLEKFELVYISAEDSSVIIPQLFGGERPMVMRDLWSPTAHANNEYLRIYEFQFLPKGFFSRLSVRVLQHYDPLCIWQNGMVLQPAGQLWGGAAKSFDSQCLIEYDSVNFILKVSIRDDNKQQQLLKSIVDLVSSFILWYFPGRLSNVRVACTHCTNQHIENPTMYTLDYLENQASLGQTNVICKAQLGGIIHETLSPRTTKIDIYSLAFEVTFNSNKFSVIPYETLKFGPQLGSGSYANVYRGIWNGSEVAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGVSLSPFCLVTELLQYGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILLGGSSMDNLVAKVGDFGLSIKPIGKEVKGRKVWNWRWLAPECMGDGQYTEKIDIYSYAIVLWEIITRDLPFEEYVDQLKWNSIIEDKIMKGLRPTIPNECPPDMKQLITDCWSGDPKKRPSFNSILERLSTMQKTFNLNERLEFCKQLPPINEDQINQQQQQPPPQSQAAQQQQPSTSTPPLSQHQQKLSISNLQLNNLLNNHNSNGSNSSIQSSLSHNNNNLNNNINNNNNNNNNNNNNSSGGSSGVSHSGSSGNNFVIPIITAIANGGIGSGGNQHQQNGSSTPHSNSQSNSGSSSVYESGDGSLSSAGSFKILRYEMVLPVAFTSTIHSLYPVQNNKNEVFVWCGMGDGSVCVINSATRQIVSTSRIADSSRILGFSLIRKCTPSSSSVTLTSRSSLNLSSLASGSTPSPYSSGGSGGSLGSSYQPICPTIEEDSHIWAFYNEGILCFEAKSFKLLKTIKTNFITSLVDEGESVWSNCKEKTSCIKVISKSKLKTKKLMNVKTLDAQITTILIHHSSVGAVGASRVWLGTDRGMIFILEYPSMAPIAHHESHGGALIHTIKRMDRFVITCSERVICIFDESGIIKKRLDGLASRVLSLLILDTYIIGACYDSTILVWDSKQNFRMVQSLKKKHTDAISSLAFALSPQGKPQLWVGGWDKKITTYSFFEDLESSLSIALQTPPPSSYPTLATPRLGLVNVSKSKLFG
Protein: Superoxide dismutase (EC 1.15.1.1) (Q6P980)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}.
Interaction partners:
- Superoxide dismutase
- Death-associated protein 3.
- Large ribosomal subunit protein uL15m
- Mitochondrial ribosomal protein L13
- Parkinson disease protein 7 homolog
- Large ribosomal subunit protein uL3m
- Catalase
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL29m
- Mitochondrial ribosomal protein L46.
Sequence:
MLCRVGYVRRCAATFNPLLGAVTSRQKHALPDLTYDYGALEPHICAEIMQLHHSKHHATYVNNLNVTEEKYQEALAKGDVTTQVSLQPALKFNGGGHINHTIFWTNLSPNGGGEPQGELLEAIKRDFGSFQKMKEKISAATVAVQGSGWGWLGFEKESGRLRIAACANQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYVKAIWNVVNWENVSERFQAAKK