wanglab/gogpt-training-data huggingface dataset:
Protein: G-patch and R3H domain-containing protein C30B4.02c (O74363)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43
- U3 small nucleolar RNA-associated protein 22
- Protein pxr1
- Probable ATP-dependent RNA helicase prh1
- ATP-dependent RNA helicase dbp4
- Uncharacterized protein C13G1.09
- U3 small nucleolar RNA-associated protein 6
- Suppressor of glycerol defect protein 1
- U3 small nucleolar RNA-associated protein 25
- ATP-dependent RNA helicase has1
Sequence:
MSNFDDLQILDQLQTSARFRGDTRIRRFKGSNNSKSPFGLNPSSRISQWPRITFIRAKDNYNPAEELCQLIDEQNAHNEAKHQSKEIMLPKETNVKSCEDLSKTGEIKALDIVLFKAITSKGDTLKVKKIPEYAEAFDTTKNVEVSSFPEKSMNENVLIQHSLNLAPSDKEISSTEESEQLCYKEQESEKELYSKDNDDSLDILNVPNLVNDDIANNNAAPPPPLAQAQEQLSTENEDEFDIDDTTDKMTTFTMNKFADLSVLEEDDDDEDEDEELEGEKEEEEEEKEKPEISNYDETEGKVNFSLEDSESLEFDEGSDDYDYAKLTTELVGNTDSLAEDEDDILEEDEDEDEEELLAIFDASDDSEIEAYLSIGDTLQNDFTIYDYDSEDEEYNNPSTQKTEKVSQSKKGAKVKEEKGLKKDRKLPKKMRKAQKKLERKAGKAVAARMGDAFSNSLDDESMNLYAELQEQWLKDKSKKARRRAEREKLRSEGLLGKKSKKKLLRESQKPSSSDSDNASLTRIDKIFINDVYQRMQQFKHSAIEEISLPPCRKYVRRLVHALANDLNLKSRSYGSGNKRYTMLSKTHKFDASSVDLVSLTRIMERLQTRVEYQSFSKSGRKSRMTVSSVRSSKATRVYDGQIVGEDAPEISKENPGRRLLEKLGWYAGKGLGHPENEGSKDSLRAIVKVSRSGLG
Protein: Protein tyrosine phosphatase Meg2, isoform D (Protein tyrosine phosphatase Meg2, isoform E) (Protein tyrosine phosphatase Meg2, isoform H (EC 3.1.3.-, EC 3.1.3.48)) (Protein tyrosine phosphatase Meg2, isoform I) (Q8IRM6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLAGFDEREPDSE
Protein: Vacuolar protein sorting-associated protein 4 (Q5AG40)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Pre-vacuolar protein sorting protein involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex. Required for extracellular secretion of the secreted aspartyl proteases SAP2, SAP4, SAP5, and SAP6. Its regulation of the pre-vacuolar secretory pathway is critical for virulence.
Subcellular location: Endosome membrane {ECO:0000250|UniProtKB:P52917}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- Vta1p
- Vacuolar protein-sorting-associated protein 46
- Vacuolar-sorting protein SNF7
- ESCRT-III subunit protein
- ESCRT-III subunit protein
- Cta1p
- Ist1p
- Vacuolar protein-sorting protein BRO1
- ESCRT-III subunit protein
- VPS4-associated protein 1
Sequence:
MSGASDFLSKGIDLVQKAIDADTATRYEEAYKLYYNGLDYLMLAIKYEKNPKSKELVKSKFTEYLTRAEQLKDHLEKQAQNKSTAESSVNGSTKAKKSNGDGNGSGDDNDDADTKKLRGALAGAILSEKPNVKWSDIAGLDAAKEALKEAVILPVKFPQLFVGNRKPTSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESERLVKQLFTMARENKPSIIFIDEVDALCGPRGEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDAAVRRRFERRIYIALPDVEARTRMFEINIGDVPCECTPHDYRTLAEMTDGYSGHDVAVVVRDALMQPIRKIQQATHFKPVIDETDGKEKLTPCSPGDEGAREMNWMDLATDELKEPPLTIKDFIKAIKNNRPTVNEADIAQHVKFTEDFGQEGN
Protein: Golgin subfamily A member 8B (Golgin-67) (A8MQT2)
Organism: Homo sapiens (Human)
Function: May be involved in maintaining Golgi structure.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:10677249}; Peripheral membrane protein {ECO:0000269|PubMed:10677249}.
Interaction partners:
- Golgin subfamily B member 1
Sequence:
MAEETGQSKLAAAKKKFKEYWQRNRPGVPAAAKRNTKANGSSPETAASGGCHSSEASSSASSSLHARQSPCQEQAAVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEKKKLNTDLYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEWSLCAVAATQKKKPDGFSSRSKALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLLNRGQKERLREQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQVMETLTSAEKEPEAAVPASGTGGESSGLMDLLEEKADLREHVEKLELGFIQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQGGEEGEAAGAAGDGVAACGSYSEGHGKFLAAARNPAAEPSPGAPAPQELGAADKHGDLCEASLTNSVEPAQGEAREGSSQDNPTAQPVLQLLGEMQDHQEHPGLGSNCCVPCFCWAWLPRRRR
Protein: MEL-11 (cGMP-dependent protein kinase interacting domain-containing protein) (G5EEB3)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGQDDEDDAHMLQAKQQITFNVVNKRKDQLRRWQSSEMNAEAARRTKRPKVQFQDSDIFLSACMSGDEEEVEELLNKGANINTCTVDGLTALHQSVIDSKPEMVRFLCEKGADVNAQDNEGWTPLHAAACCGNVAIVRYLCQHGADLSIVNSDKELALDLAVDEQCRDYLDDDYKRQMIDLDACRDQELQTMLKDVNMWMSQGEYRDIPHHRTGGTAMHVAAGRGYTQLLELLIKAGGNVRAQDVEGWTPLHAAAHWAERDACKILLENGAELSDLTFTGADVLGVADKECIDYLVELADTVKVQNKRKSPGSGSQPPTSILQEKNHRMPSHEEHVLTSERKRDLQHKDQHSENEFLHSHPSTASVGSTTSSNTNTTTTTIVIGENDISAAQKDSRESSKESAVDDEEYVAEDEMEEAEEDEEEEDVEEEEEEKSEAELKNGKEISPLRSETTSSRSISITRSLDGYTDRSSSGRETSAEMSEAASSASTGTTSSSSRFTSSTPSSQRSAAGSVHTETPRSSMENSSSVGSGDQNVSATIPIVPLSAPPKAVHQSPSSWINRGVPLSSRSSTSSVTRSSSTPVSEIISPPSSIHSQLSFPSVSNTTTTTATVAPTSSTVPSTPVSNVMAATISSTAKNTPSPAGSVTTINATFSKPSRWQSKTVTESEAERRNNSRMQRQHRRSTQGVTKEQLEEASKFATDEVARRNSQVLSTYPNSLHARLASEEKDLSSTSDDLKDGDVSTTATVSLINSPNSNSANVRRKSQGLSISRSNRRATGPVNPEDLAPAMSLRLATAQPYSPASVRSNAGTLPTMTSRFSEKAQSLPPASNGMSSTQPLSTRSAIVAGLSSAPSMRTTAPLSSTATSSRFMPSSSLSSNGSSANQQPSSIYGLQSRPTETNLNYKALFEKERSECERLRREMEEMRRSQTADSYRGASTQLAWRARNASPSAQPHNLSVAKSTSLASFDENERRSMERKISDLELQLKTATNLRMENQRLKEENGALVRVISKMTI
Protein: Uncharacterized protein (Q38E67)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQELAVFKRPHLHACSEYVDVAVELAPLRRCESFTDFLQLLQGELEFIYGSAPKSFNNAILYSTHEAPCSFSCYFSEKQLEMLRNFDEACEKESQMRVSYENVVAEYDAKVEENKDRKMNRRRRMEMEKARKRVKVMDRDVKQAEYEVKKSAQKLANIFQIAALRVLLN
Protein: Magnetosome protein MamD (MM21.9) (Q93DY2)
Organism: Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)
Function: Helps regulate magnetite crystal morphology, probably in a single growth axis (By similarity). Plays a role in regulating magnetite crystal size. Probably binds Fe(2+) (By similarity).
Subcellular location: Magnetosome membrane {ECO:0000269|PubMed:11571158, ECO:0000269|PubMed:14766587, ECO:0000269|PubMed:29243866}; Single-pass membrane protein {ECO:0000255}. Note=Purified magnetosomes remain attached to each other. {ECO:0000269|PubMed:11571158}.
Interaction partners:
- Magnetosome protein MamC
- Magnetosome protein MamF
- Magnetosome formation protease MamE
- Magnetosome protein MamB
- Magnetite biomineralization protein Mms6
- Magnetosome protein MamQ
Sequence:
MQDLFLAKVESAMQASQVGALAGQTATVSSVSATTNLATITPTTAGQAPIIVKLDAARQVTELQALMGKTVLVGKTPTTIGGIGNWIALTPAAGAKTGAAVAGTGQLVMMKVEGTGAAIKLPALAGKSFIVAQPPVAAGTKAAGMLYLNPVGGGDMVAINIQNAMTQTGGLVGKTFTVAPSPVIGGTTGKFLVLKPMATGVGKAVGSGAVVAKFVPAAVTGTGGAAAIGAGSATTLMATGASTITPVTAAAAGSAMLTAKGVGLGLGLGLGAWGPFALGAIGLAGVVALYTWARRRHGAPDVSDDALLAAVGEE
Protein: Zinc finger MYM-type protein 3 (Zinc finger protein 261) (Q14202)
Organism: Homo sapiens (Human)
Function: Plays a role in the regulation of cell morphology and cytoskeletal organization.
Subcellular location: Nucleus {ECO:0000269|PubMed:36586412}.
Interaction partners:
- General transcription factor II-I
- Lysine-specific histone demethylase 1A FAD-dependent demethylase 1A)
- Histone deacetylase 1
- Histone deacetylase 2
- Zinc finger MYM-type protein 2
- BRCA1-A complex subunit RAP80
- REST corepressor 1
- Small ubiquitin-related modifier 2
- Chromodomain-helicase-DNA-binding protein 4
- Genetic suppressor element 1
Sequence:
MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEELPQGQPQSPNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSVSQRAGRSAVGTKMTCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPSGKKTCTFCKKEIWNTKDSVVAQTGSGGSFHEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYTKTGSPGPELLFHEGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQRTSPEGGIHLSCHYCHSLFSGKPEVLDWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKSKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSPESKPQTPSQTKVENSNTVRTPEENGNLGKIPVKTRSAPTAPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTEEWKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTDKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGPARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRTMRKGQKRLVLSESCSRDSMSSQPSCTGLNYSYGVNAWKCWVQSKYANGETSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDEAPILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD
Protein: Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin) (Q13561)
Organism: Homo sapiens (Human)
Function: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. In the dynactin soulder domain, binds the ACTR1A filament and acts as a molecular ruler to determine the length (By similarity). Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:8647893}. Membrane {ECO:0000269|PubMed:8647893}; Peripheral membrane protein {ECO:0000269|PubMed:8647893}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0A5G2QD80}.
Interaction partners:
- Dynactin subunit 4
- Dynactin subunit 3
- Alpha-centractin
- Dynactin subunit 1
- Actin-related protein 10
- Dynactin subunit 5
- Protein bicaudal D homolog 2
- Dynactin subunit 6
- Beta-centractin
- Cytoplasmic dynein 1 intermediate chain 1
Sequence:
MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
Protein: Probable intron-encoded endonuclease Cox1-I1b (EC 3.1.-.-) (P22191)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase subunit 1
- ATP synthase subunit a
- Uncharacterized 91 kDa protein in cob intron
- Uncharacterized cox1 intron-2 37.2 kDa protein
- NADH-ubiquinone oxidoreductase 51 kDa subunit homolog SPBC18E5.10, mitochondrial
- NADH-ubiquinone oxidoreductase 24 kDa subunit homolog C11E3.12, mitochondrial
Sequence:
MKPQTKLSENSSRCEKVLYSEVITQLIYFLTSKKITNLGKIRLVKSIRDSFLSQLENILCFFLVYRTTYSFGVCLMKRFLFNKFFNRHPFTRVKSCFSSSSPSKFSFTQWLVGFTDGDGCFSISKQKIKNGKNKWSLTFKLTQNLYNYRILYFIKRNLGIGSLYKESSTNTVIYRLRRREHLKKIIDIFDQFPLLTKKYWDYYLFKKAFLILEDANLNSFEKNSKLEEIRIEKKSLKQYSPVNLEKYLTKSWLIGFIEAEGSFYLLQKSPVRIIHGFEITQNYEQPLLAQISEFLFNSQISPKIKSKKNSLITNYSLSTSSKERMLFLSSYFENCFKGVKSLEFKIWSRSLRKNYNFEQLLRARDLIRKLKNKYSRGSQHPKDK
Protein: Neurogenic differentiation factor (F1QWM8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR015618}.
Interaction partners:
- Achaete-scute homolog 1a
- Scratch family zinc finger 2.
- Helix-loop-helix protein 2
Sequence:
MMTKPYGKPGDVTELVSSLGWMDEDLSSQDGDRTPEIGHYSLHRSNRGPLEIGSEDMDEEEEEEEDEEMGLDGEKAPKRRGPKKKKMTKARQERFRARRIKANARERSRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLESGQSPESHGFVEMLCKGLSQPTSNLVAGCLQLGPTTMLKLDEKCGVPGAGVPQGHPISYPSPGLPSPPYGTMEASHLLHLKGYKGPPYENSSPNECSSGTPPYDGPLTPPLSISGNFALKQEPSPREAERNFTPHPTHYISSHPYPPTSLAGLPAPQGHPLFPGSRYELPLDMAFEPFAPSHIVTSQMSSIYSE
Protein: Nuclear migration protein nudC (Nuclear distribution protein C homolog) (c15) (Q63525)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (By similarity). Necessary for cytokinesis and cell proliferation (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9Y266}. Midbody {ECO:0000250|UniProtKB:Q9Y266}. Note=A small proportion is nuclear, in a punctate pattern (By similarity). In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center (By similarity). Distributed throughout the cytoplasm of non-migrating cells (By similarity). {ECO:0000250|UniProtKB:Q9Y266}.
Interaction partners:
- Platelet-activating factor acetylhydrolase IB subunit alpha
- Serine/threonine-protein kinase PLK1
- Nuclear distribution protein nudE-like 1
- Nuclear distribution protein nudE homolog 1
- CAP-Gly domain-containing linker protein 1
- Inner centromere protein
- Shugoshin 1
- CLIP-associating protein 2
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Small ribosomal subunit protein eS27
Sequence:
MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFNHHNQLAQKARREKRARQETERREKAERAARLAKEAKAETPGPQIKELTDEEAERLQLEIDQKKDAENHEVQLKNGSLDSPGKQDAEEEEDEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFRVSFRLKGKDVVVDIQRRHLRVGLKGQAPVIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
Protein: Jasmonate-induced oxygenase 3 (EC 1.14.11.-) (2-oxoglutarate-dependent dioxygenase JOX3) (Jasmonic acid oxidase 3) (Protein JASMONATE-REGULATED GENE 21) (Q9LY48)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: 2-oxoglutarate-dependent dioxygenase involved in the oxidation of jasmonate (JA), a stress-induced phytohormone synthesized in response to attack by pathogens and herbivores, which triggers the activation of defense responses via the JA-mediated signaling pathway. Converts JA to 12-hydroxyjasmonate (12OH-JA), an inactive form of JA. Is specific to free JA, and cannot oxidize the bioactive form jasmonoyl-L-isoleucine (JA-Ile) or other JA-amino acid conjugates. Prevents over-accumulation of JA and indirectly its bioactive form JA-Ile under stress response. Acts as negative regulator of JA-mediated defense signaling, by contributing to 12OH-JA accumulation, which represses JA defense responses upon infection by the fungal pathogen Botrytis cinerea. Acts as negative regulator of JA-mediated defense responses upon infestation by the herbivorous caterpillar Mamestra brassicae.
Interaction partners:
- 2-nitropropane dioxygenase-like protein
- AT4g22610/F7K2_190
- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
- Hydroxyproline-rich glycoprotein family protein
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- L-ornithine N5-acetyltransferase NATA1
- Eukaryotic aspartyl protease family protein
- Probable E3 ubiquitin-protein ligase RHY1A
Sequence:
MNIFQDWPEPIVRVQSLSESNLGAIPNRYVKPLSQRPNITPHNKHNPQTTTIPIIDLGRLYTDDLTLQAKTLDEISKACRELGFFQVVNHGMSPQLMDQAKATWREFFNLPMELKNMHANSPKTYEGYGSRLGVEKGAILDWSDYYYLHYQPSSLKDYTKWPSLPLHCREILEDYCKEMVKLCENLMKILSKNLGLQEDRLQNAFGGKEESGGCLRVNYYPKCPQPELTLGISPHSDPGGLTILLPDEQVASLQVRGSDDAWITVEPAPHAFIVNMGDQIQMLSNSIYKSVEHRVIVNPENERLSLAFFYNPKGNVPIEPLKELVTVDSPALYSSTTYDRYRQFIRTQGPRSKCHIDELKSPR
Protein: Calmodulin-like protein 30 (Q9ZQE6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potential calcium sensor.
Interaction partners:
- Probable calcium-binding protein CML47
- Probable calcium-binding protein CML45
- Probable calcium-binding protein CML40
- Probable calcium-binding protein CML48
Sequence:
MSNVSFLELQYKLSKNKMLRKPSRMFSRDRQSSGLSSPGPGGFSQPSVNEMRRVFSRFDLDKDGKISQTEYKVVLRALGQERAIEDVPKIFKAVDLDGDGFIDFREFIDAYKRSGGIRSSDIRNSFWTFDLNGDGKISAEEVMSVLWKLGERCSLEDCNRMVRAVDADGDGLVNMEEFIKMMSSNNV
Protein: Histone-lysine N-methyltransferase ATXR5 (EC 2.1.1.369) (Protein SET DOMAIN GROUP 15) (Trithorax-related protein 5) (TRX-related protein 5) (Q8VZJ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1). Has much higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. Influences which sets of rRNA gene variants are expressed or silenced.
Subcellular location: Nucleus {ECO:0000269|PubMed:16771839}. Plastid, chloroplast {ECO:0000269|PubMed:16771839}. Note=Never found in plastids and the nucleus within the same cell.
Interaction partners:
- Histone H3.1
- Histone H3.3
- Histone H3-like 5
- Histone H3-like 3
- Histone H3-like 2
- Histone H3-like 4
- Histone H3-like 1
- Histone H3-like centromeric protein CENH3
- Histone-lysine N-methyltransferase ASHH2
- Histone-lysine N-methyltransferase ASHH1
Sequence:
MATWNASSPAASPCSSRRRTKAPARRPSSESPPPRKMKSMAEIMAKSVPVVEQEEEEDEDSYSNVTCEKCGSGEGDDELLLCDKCDRGFHMKCLRPIVVRVPIGTWLCVDCSDQRPVRRLSQKKILHFFRIEKHTHQTDKLELSQEETRKRRRSCSLTVKKRRRKLLPLVPSEDPDQRLAQMGTLASALTALGIKYSDGLNYVPGMAPRSANQSKLEKGGMQVLCKEDLETLEQCQSMYRRGECPPLVVVFDPLEGYTVEADGPIKDLTFIAEYTGDVDYLKNREKDDCDSIMTLLLSEDPSKTLVICPDKFGNISRFINGINNHNPVAKKKQNCKCVRYSINGECRVLLVATRDISKGERLYYDYNGYEHEYPTHHFL
Protein: Ribonuclease 8 (RNase 8) (EC 3.1.27.-) (Q8TDE3)
Organism: Homo sapiens (Human)
Function: Has a low ribonuclease activity.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Angiogenin
Sequence:
MAPARAGCCPLLLLLLGLWVAEVLVRAKPKDMTSSQWFKTQHVQPSPQACNSAMSIINKYTERCKDLNTFLHEPFSSVAITCQTPNIACKNSCKNCHQSHGPMSLTMGELTSGKYPNCRYKEKHLNTPYIVACDPPQQGDPGYPLVPVHLDKVV
Protein: Mitochondrial methylmalonyl-CoA epimerase (VOC domain-containing protein) (G5EEG4)
Organism: Caenorhabditis elegans
Interaction partners:
- Propionyl-CoA carboxylase alpha chain, mitochondrial
- Probable methylmalonyl-CoA mutase, mitochondrial
- Propionyl-CoA carboxylase beta chain, mitochondrial
- Ethylmalonyl-CoA decarboxylase
- Methylmalonic aciduria type A homolog, mitochondrial
- Probable NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Corrinoid adenosyltransferase MMAB
- FMN hydroxy acid dehydrogenase domain-containing protein
- 2Fe-2S ferredoxin-type domain-containing protein
- MMACHC-like protein)
Sequence:
MASFRSTLALVNSAKLSLSTRTMASHPLAGLLGKLNHVAIATPDLKKSSEFYKGLGAKVSEAVPQPEHGVYTVFVELPNSKIELLHPFGEKSPIQAFLNKNKDGGMHHICIEVRDIHEAVSAVKTKGIRTLGEKPKIGAHGKEVMFLHPKDCGGVLIELEQE
Protein: Signal peptide peptidase 1 (OsSPP1) (EC 3.4.23.-) (Intramembrane protease 1) (IMP) (IMPAS) (Q6ZGL9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19688213}; Multi-pass membrane protein {ECO:0000269|PubMed:19688213}.
Interaction partners:
Sequence:
MKTHERAANLALAGLSLAPLVVKVEPNVNVILTACLAVYVGCYRSVKPTPPSETMSKEHAMRFPLVGSAMLLSLFLLFKFLSKDLVNAVLTAYFFILGIAALCATLLPSIKRFLPKEWNDNAIVWCAPFFHSLSVEFTKSQVVASIPGFFFCIWYAAKKHWLANNVLGISFCIQGIEMLSLGSFKTGAILLAGLFFYDIFWVFFTPVMVSVAKSFDAPIKLLFPTGDAARPFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTVGLTVTIIVMNWFQAAQPALLYIVPGVIGFVAVHCLWNGEVKPLLEYNESKAEEEDAVEEDTDSKQNKKEE
Protein: Serine/threonine-protein phosphatase PP1 isozyme 3 (EC 3.1.3.16) (Type one protein phosphatase 3) (P48483)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine/threonine-protein phosphatase that possesses phosphatase activity toward para-nitrophenyl phosphate (pNPP) in vitro.
Subcellular location: Nucleus {ECO:0000269|PubMed:19329567}. Cytoplasm {ECO:0000269|PubMed:19329567}.
Interaction partners:
- Protein phosphatase 1 regulatory subunit INH3
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Flowering time control protein FY
- Transducin/WD40 repeat-like superfamily protein
- Protein ANTHESIS POMOTING FACTOR 1
- Cleavage and polyadenylation specificity factor subunit 2
- Cleavage and polyadenylation specificity factor subunit 3-I
- Putative 26S proteasome non-ATPase regulatory subunit 8 homolog B
- Proton pump-interactor 2
- 30-kDa cleavage and polyadenylation specificity factor 30
Sequence:
MEDSVVDDVIKRLLGAKNGKTTKQVQLTEAEIKHLCSTAKQIFLTQPNLLELEAPIKICGDTHGQFSDLLRLFEYGGYPPAANYLFLGDYVDRGKQSVETICLLLAYKIKYKENFFLLRGNHECASINRIYGFYDECKKRYSVRVWKIFTDCFNCLPVAALIDEKILCMHGGLSPELKHLDEIRNIPRPADIPDHGLLCDLLWSDPDKDIEGWGENDRGVSYTFGADKVEEFLQTHDLDLICRAHQVVEDGYEFFANRQLVTIFSAPNYCGEFDNAGAMMSVDDSLTCSFQILKASEKKGNFGFGKNAGRRGTPPRKGGGKG
Protein: Cilia- and flagella-associated protein 20 (Q6B857)
Organism: Bos taurus (Bovine)
Function: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9Y6A4}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9Y6A4}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9Y6A4}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37327785}. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme. {ECO:0000269|PubMed:34715025}.
Interaction partners:
- Parkin coregulated gene protein
- EF-hand domain-containing family member C2
- EF-hand domain-containing protein 1
- Cilia and flagella associated protein 45.
- Protein broad-minded
- Tubulin beta-4B chain
- Cilia- and flagella-associated protein 52
- Tektin-2
- Meiosis-specific nuclear structural protein 1
- Cilia- and flagella-associated protein 95
Sequence:
MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ
Protein: Vesicle-associated membrane protein 711 (AtVAMP711) (v-SNARE synaptobrevin 7C) (AtVAMP7C) (O49377)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:15342965}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q12255}. Prevacuolar compartment membrane {ECO:0000269|PubMed:15342965}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q12255}.
Interaction partners:
- Syntaxin-22
- Syntaxin-32
- Vesicle transport v-SNARE 12
- Syntaxin-21
- Syntaxin-23
- Putative SNAP25 homologous protein SNAP30
- Vesicle transport v-SNARE 11
- Syntaxin-51
- Syntaxin-123
- Syntaxin-125
Sequence:
MAILYALVARGTVVLSEFTATSTNASTIAKQILEKVPGDNDSNVSYSQDRYVFHVKRTDGLTVLCMAEETAGRRIPFAFLEDIHQRFVRTYGRAVHTALAYAMNEEFSRVLSQQIDYYSNDPNADRINRIKGEMNQVRGVMIENIDKVLDRGERLELLVDKTANMQGNTFRFRKQARRFRSNVWWRNCKLTVLLILLLLVIIYIAVAFLCHGPTLPSCI