wanglab/gogpt-training-data huggingface dataset:
Protein: Transcriptional activator of proteases prtT (Zn(2)-C6 zinc finger-containing protein prtT) (A7BJS7)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases including a serine alkaline protease (alp1) and a metalloprotease (NpI).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
Interaction partners:
- 60S ribosomal protein L7
- Large ribosomal subunit protein uL23 N-terminal domain-containing protein
- Large ribosomal subunit protein uL18 C-terminal eukaryotes domain-containing protein
- Large ribosomal subunit protein uL2m
- KOW domain-containing protein
Sequence:
MTRTTVEPIKYEAPSWEHKSVHVSDDHRRIIPNVGDDATRPKGRIRRSMTACNTCRKLKTRCDLDPRGHACRRCLSLRIDCQLPETSERFQDSTPMWSDATTAIPSIEERLTSLERSMREMTGMLRQILNQSPSVSNISVPPLARSVHTEETASIEGNSFGPFLPKPVRLIQDLQSEFFGETNRIPVESPFLGNSFEKGILDSKLSLKLVQLFVDNFGPLVSINNQSDFHNEMRNTDSLLYSTACLLASRYVPGIPPPIVHTMNLQVRHKAVNLLWEKPPLKYESLQALALLCLWPAAGQKEFPIDGWLLSGTAINHALVSFDFLNHVPSELLIDNDIAAQLRLWNAFCLTQLHFAVGNARPFHLPQRYLDYCPRLLEHPAATVEDGKVVAEIQLYLITLRLQANEQRMRFAEVEYEEIERWKVEWAHLLGKVKQRGPSRINANYSTAGDENSTFELSLWFCQILLHRTAMRFQAESERLTSEILQGSRLIISKFLQLRFVTALRVVDQAYFIVGYAALNLCDFNFLDPLIDQIQMFLLHLSPNEDHIAYRFSCMIAEFKRRCAECNDPCSAVDGSQCSFGDARKMSMEQVQFVPPLVDSMIGGYSALEQLIPEVMPHSFPESVISGMAVTEAIPVGSAPY
Protein: Phosphatidylglycerol/phosphatidylinositol transfer protein (PG/PI-TP) (Q6FNB1)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
Interaction partners:
Sequence:
MQVKSLISSVALWGCAFTVANPIIGWGIGDVDKKAPMPPGFGETKPIPGDSPLKMCDIAEGQLLEITKLDLVPNPPKRGSKLVIKASGEIFETIEEGAYVDVEVRLGYIKLLTQTYDLCEILEDNDVDGLTCPIKKGKYDNLSKDVDIPQEVPPGKYLVTARAYTNDDDLITCITGEVYFPPPGI
Protein: Lymphocyte antigen 6 complex locus protein G5c (Q8K1T5)
Organism: Mus musculus (Mouse)
Function: May have a role in hematopoietic cell differentiation.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Lymphocyte antigen 6 complex locus protein G5b
- Lymphocyte antigen 6 complex locus protein G6c
Sequence:
MLFMAGPAASWSLRPLGLHGVPQALCAVLLTVLVMKTLVLGDTKLEDLHPQSLPLNKYLNCYRCLLETEELGCLLGSDTCLTPLGSSCVTLHIKNSSGFNVMVSDCYSKEQMVHCSYTRASPVFGFWIFYQCCFLDFCNNPDNRKNSMH
Protein: Mitochondrial import inner membrane translocase subunit TIM44 (Q5A7M2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273, ECO:0000256|PIRNR:PIRNR037871}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM23
- Mitochondrial import inner membrane translocase subunit TIM17
- Mitochondrial import inner membrane translocase subunit TIM16
- GrpE protein homolog
- Mitochondrial import inner membrane translocase subunit TIM14
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit TIM21
- Heat shock protein SSC1, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM54
- Hsp70 family ATPase
Sequence:
MLRSGIIKAQPATAIIRPLSRCFHYTNINFNDKPPSSDSPLKVFFDTFKTEVKKSNELKENIKALQDESGRMAESEAFKRAKEAYAKAQLGSTAAGKVLKKGAETVGDAAYKAWESPVGKGVRTGVKVTADVADKAFEPVRKTQVYKDMSEVIDDGSSTAYGGFLTKEQREALRMKELERKKKQGFQGPVRENDEAGGALVATEHKPTGPTMGEKWENFKLKSPIGRGVVYLQERWEESENGLIALIRTIVEKVTGFFSETEQAKVVKQLKLMDPSFRLTDFQRTLTNYIVPEVVDAYIKNDAKVLKEWLSEAPYNVWEANNKQFIQQGLFSDSRVLDIRGVEIVTCKSLQPNDVPVIVVSCRAQEIHLYRKAKTGEIAAGTEDHIQLSTYAMVLTRIPEEFDNKVTDGWKIVEFARGGSRPFH
Protein: Large ribosomal subunit protein mL43 (39S ribosomal protein L43, mitochondrial) (L43mt) (MRP-L43) (Mitochondrial ribosomal protein bMRP36a) (Q8N983)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042}.
Interaction partners:
- Large ribosomal subunit protein mL44
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein bL20m
- Large ribosomal subunit protein mL49
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS7m
- Large ribosomal subunit protein bL34m
Sequence:
MTARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSGLDVIRIRKPFHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDPAPAQDTGLRLSAVAPQILLPGWPDPPDLPTVDPISSSLTSAPAPMLSAVSCLPIVPALTTVCSA
Protein: Guanine nucleotide-binding protein alpha-16 subunit (Q9N2V6)
Organism: Caenorhabditis elegans
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle.
Interaction partners:
- Spindle apparatus protein lin-5
- G-protein regulator 1
- Guanine nucleotide-binding protein subunit beta-1
- Chaperone ric-8
- G-protein regulator 2
- Protein let-99
- G protein gamma domain-containing protein
- Regulator of G-protein signaling rgs-7
- Tetratricopeptide repeat protein 28
- Guanine nucleotide-binding protein subunit gamma
Sequence:
MGCIMSQEDEAAKRRSKKIDRLLKEDGENSMRTIKLLLLGAGESGKSTILKQMRIIHDVGYTTEERKVFRGVVYGNIILSLNAIIHAMEQLKISFTTLDHESDARKLLMFSTTGEEDELPEELVVLMKSVWSDSGIQKALERSREYQLNDSAGYYLSQLDRICAPNYIPTQDDILRTRIKTTGIVETQFVYKDRLFLVFDVGGQRSERKKWIHCFEDVTALIFCVALSEYDMVLVEDCQTNRMRESLKLFDSICNNKWFVETSIILFLNKKDLFEEKIVRSPLTHCFPEYTGANNYEEASAYIQQQFEDMNKRTTGEKNQEIYTQFTCATDTNNIRFVFDAVTDIIIRDNLRTCGLY
Protein: Mitogen-activated protein kinase kinase kinase 18 (EC 2.7.11.25) (Q9ZVP5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the abscisic acid (ABA) signaling pathway that acts as ABA signal transducer in the context of abiotic stresses. Triggers MPK1, MPK2, MPK7 and MPK14 activation in a MKK3-dependent manner and MPK6 activation in a MKK3-independent manner. Mediates the ABA-dependent activation of the MKK3-MPK7 module. Positive regulator of ABA responses leading to the induction of gene expression (e.g. RD29B and RAB18) and involved in various responses including stomatal development, stomatal movement, inhibition of germination and root growth. Promotes leaf senescence.
Subcellular location: Nucleus {ECO:0000269|PubMed:26443375, ECO:0000269|PubMed:26852793}.
Interaction partners:
- Mitogen-activated protein kinase kinase 3
- Mitogen-activated protein kinase kinase kinase 17
- Protein phosphatase 2C 56
Sequence:
MNWTRGKTLGRGSTATVSAATCHESGETLAVKSAEFHRSEFLQREAKILSSLNSPYVIGYRGCEITREPFHNNGEATTYSLLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQILLGLEYIHNSKGIAHCDIKGSNVLVGENGEAKIADFGCAKWVEPEITEPVRGTPAFMAPEAARGERQGKESDIWAVGCTVIEMVTGSQPWIGADFTDPVSVLYRVGYLGELPELPCSLTEQAKDFLGKCLKKEATERWTASQLLNHPFLVNKEPELVTGLVTNSPTSVTDQMFWRSVEEEVSEDRSSWWECHEDERIGVLSWIGHVVVESTWDLDGEDWITVRRN
Protein: (+)-pulegone reductase (EC 1.3.1.81) (Q6WAU0)
Organism: Mentha piperita (Peppermint) (Mentha aquatica x Mentha spicata)
Function: Monoterpene synthase that catalyzes the specific reduction of the 4,8-double bond of (+)-pulegone to produce both (-)-menthone and (+)-isomenthone in a 70:30 ratio. Unable to utilize either (-)-isopiperitenone or (+)-cis-isopulegone, or to catalyze the reverse reaction with (-)-menthone or (+)-isomenthone. Has an absolute requirement for NADPH.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MVMNKQIVLNNYINGSLKQSDLALRTSTICMEIPDGCNGAILVKNLYLSVNPYLILRMGKLDIPQFDSILPGSTIVSYGVSKVLDSTHPSYEKGELIWGSQAGWEEYTLIQNPYNLFKIQDKDVPLSYYVGILGMPGMTAYAGFFEICSPKKGETVFVTAAAGSVGQLVGQFAKMFGCYVVGSAGSKEKVDLLKNKFGFDDAFNYKEESDYDTALKRHFPEGIDIYFDNVGGKMLEAVINNMRVHGRIAVCGMVSQYSLKQPEGVHNLLKLIPKQIRMQGFVVVDYYHLYPKFLEMVLPRIKEGKVTYVEDISEGLESAPSALLGVYVGRNVGNQVVAVSRE
Protein: Aquaporin-7 (D3TZW4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MEDGSIQGRMAPNVGSMLKIKNEYIRVALAESLCTFIMMVFGLGTVAQVVTGEGYFGEYLSINIGFGLAVAMGVHVGGKVSGAHMNAAVSFTMCVFGRLRWKMLPLYAFAQFLGSFLAAGTIFSLYYDAINHFCGGNLTVSGPKATAGIFATYPAPYISVYTGFFDQVAGTGLLLLCLMALSDQRNQPLVSGGEAVGVGLLVMLIGISMGSNSGYAINPTRDLGPRLFTLIAGWGTEVFRAGNCWWWVPLVAPFIGGVLGALIYKALVELHHPDLKNTTTRPAVDPECIPLDKCKNGRIEIPV
Protein: Proline dehydrogenase 2 (PRODH 2) (EC 1.5.5.2) (Proline oxidase 2) (P94390)
Organism: Bacillus subtilis (strain 168)
Function: Converts proline to delta-1-pyrroline-5-carboxylate. Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.
Interaction partners:
- 1-pyrroline-5-carboxylate dehydrogenase 2
- 1-pyrroline-5-carboxylate dehydrogenase
- Pyrroline-5-carboxylate reductase 1
- Pyrroline-5-carboxylate reductase 3
- Pyrroline-5-carboxylate reductase 2
- High-affinity proline transporter PutP
- Proline dehydrogenase 1
- Proline-responsive transcriptional activator PutR
- Osmoregulated proline transporter OpuE
- Betaine aldehyde dehydrogenase
Sequence:
MITRDFFLFLSKSGFLNKMARNWGSRVAAGKIIGGNDFNSSIPTIRQLNSQGLSVTVDHLGEFVNSAEVARERTEECIQTIATIADQELNSHVSLKMTSLGLDIDMDLVYENMTKILQTAEKHKIMVTIDMEDEVRCQKTLDIFKDFRKKYEHVSTVLQAYLYRTEKDIDDLDSLNPFLRLVKGAYKESEKVAFPEKSDVDENYKKIIRKQLLNGHYTAIATHDDKMIDFTKQLAKEHGIANDKFEFQMLYGMRSQTQLSLVKEGYNMRVYLPYGEDWYGYFMRRLAERPSNIAFAFKGMTKK
Protein: Regenerating islet-derived protein 3-alpha (REG-3-alpha) (Hepatointestinal pancreatic protein) (HIP/PAP) (Human proislet peptide) (HIP) (Pancreatitis-associated protein 1) (Regenerating islet-derived protein III-alpha) (Reg III-alpha) [Cleaved into: Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein 3-alpha 15 kDa form] (Q06141)
Organism: Homo sapiens (Human)
Function: Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Binds membrane phospholipids and kills bacteria by forming a hexameric membrane-permeabilizing oligomeric pore.
Subcellular location: Secreted {ECO:0000269|PubMed:1469087}. Note=Found in the apical region of pancreatic acinar cells. {ECO:0000269|PubMed:1469087}.
Interaction partners:
- Lithostathine-1-alpha
- Defensin alpha 5
- Defensin-6
- Regenerating islet-derived protein 3-gamma
- Lithostathine-1-beta
Sequence:
MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD
Protein: WH2 domain-containing protein (F5GUF0)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MVAPIGMTMHHHPQQNVHPSQQRGGAPAAARGSPNVKRPTEAPPPVNLDHLPPPDMSILSIDDDDDDLPPPPPPLLMNTSIVHQLPAEAPSTIQFVEPSAAPPTNIPPPPPPPPPMVISSAAASFAAPAPKPSADGEAAGTNSPVAPKQPDARSDLLAQIQSGIKLKKVQRAEAEAAENAALEANNVAAILKRRMDQVMGNDDSSSEEGADDDEWDD
Protein: Pentatricopeptide repeat-containing protein At5g66520 (Q9FJY7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DEAD-box ATP-dependent RNA helicase 56
Sequence:
MNVISCSFSLEHNLYETMSCLQRCSKQEELKQIHARMLKTGLMQDSYAITKFLSFCISSTSSDFLPYAQIVFDGFDRPDTFLWNLMIRGFSCSDEPERSLLLYQRMLCSSAPHNAYTFPSLLKACSNLSAFEETTQIHAQITKLGYENDVYAVNSLINSYAVTGNFKLAHLLFDRIPEPDDVSWNSVIKGYVKAGKMDIALTLFRKMAEKNAISWTTMISGYVQADMNKEALQLFHEMQNSDVEPDNVSLANALSACAQLGALEQGKWIHSYLNKTRIRMDSVLGCVLIDMYAKCGEMEEALEVFKNIKKKSVQAWTALISGYAYHGHGREAISKFMEMQKMGIKPNVITFTAVLTACSYTGLVEEGKLIFYSMERDYNLKPTIEHYGCIVDLLGRAGLLDEAKRFIQEMPLKPNAVIWGALLKACRIHKNIELGEEIGEILIAIDPYHGGRYVHKANIHAMDKKWDKAAETRRLMKEQGVAKVPGCSTISLEGTTHEFLAGDRSHPEIEKIQSKWRIMRRKLEENGYVPELEEMLLDLVDDDEREAIVHQHSEKLAITYGLIKTKPGTIIRIMKNLRVCKDCHKVTKLISKIYKRDIVMRDRTRFHHFRDGKCSCGDYW
Protein: Pyruvate kinase (EC 2.7.1.40) (Q98TA0)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
QLFEELRRLTPLSNDPTEVTAIGAVESSFKCCAGAVIVLTTTGRSAQLLSRYRPRCPIVAVTRSPQVARQAQLLRGVFPVLFHPLPAPVWADDVDNRVNFGMNIGKARGFFKTGDLVIVVTG
Protein: Tmem88a protein (Transmembrane protein 88 a) (Transmembrane protein 88a) (Q6P0G3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSLPRNGTLEKLASLQTPAERGEPESPHPRLHHTGSISSSTPANASSTGVVVPPPYSVAGSAGNECPLELRGSLDCWACSVLVTAQNLIIAALNVGLAGFIFGLILLPSLVMVVFGFLCHSTVQRHGTSLYCSDLLDDGGCVALLVVGFLLLAPLLVLALAAYCRMARHLQLGLCFIPYSRAVYKNLPASRHRGLGGCCGQQGAGESEGKGSVWV
Protein: Proteasome subunit beta type-6 (EC 3.4.25.1) (Differentiation-associated proteasome subunit 1) (DAPS-1) (Q55GJ6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular location: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809, ECO:0000269|PubMed:8130037}. Nucleus {ECO:0000269|PubMed:8130037}.
Interaction partners:
- Proteasome subunit beta type-4
- Proteasome subunit alpha type-2
- Proteasome subunit beta type-7
- Proteasome subunit beta type-1
- Proteasome subunit alpha type-6
- Proteasome subunit alpha type-1
- Proteasome subunit alpha type-5
- Proteasome subunit alpha type-3
- Proteasome subunit beta type-3
- Proteasome subunit beta type-5
Sequence:
MEAPEWLDNAVDLGTSIMAVEYDGGVIMGADSRTTTGAYIANRVTNKITPIHERIYCCRSGSAADTQAISDYVRYYLEMHTSELCDEPDVKTAASLFQLLCYSNKNNLMAGIIVAGWDKHQGGSVYNISLGGSMVKQPFAIGGSGSTYIYGYCDSKFKPKMTKDECIEFVQNSLALAMFRDGSSGGVIRLCIIDKNGVERKMIPGNNLPRFWEG
Protein: Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) (Homeobox protein NK-3 homolog B) (P97503)
Organism: Mus musculus (Mouse)
Function: Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Runt-related transcription factor 2
Sequence:
MAVRGSGTLTPFSIQAILNKKEERGGLATPEGRPAPGGTEVAVTAAPAVCCWRIFGETEAGALGGAEDSLLASPARTRTAVGQSAESPGGWDSDSALSEENEGRRRCADVPGASGTGRARVTLGLDQPGCELHAAKDLEEEAPVRSDSEMSASVSGDHSPRGEDDSVSPGGARVPGLRGAAGSGASGGQAGGVEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYYYPYYCLPGWALSTCAAAAGTQ
Protein: Anion exchange protein 4 (AE 4) (Anion exchanger 4) (Sodium bicarbonate cotransporter 5) (Solute carrier family 4 member 9) (Q96Q91)
Organism: Homo sapiens (Human)
Function: Probable apical anion exchanger of the kidney cortex.
Subcellular location: Basolateral cell membrane {ECO:0000250|UniProtKB:A0A494BA31}; Multi-pass membrane protein {ECO:0000255}. Note=Localized in the basolateral membrane of the cortical collecting duct (CCD)and submandibular gland (SMG) duct. {ECO:0000250|UniProtKB:A0A494BA31}.
Interaction partners:
- Ankyrin repeat and KH domain-containing protein 1
Sequence:
MEMKLPGQEGFEASSAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPLLFIQLNELLGWPQALEWRETGSSSASLLLDMGEMPSITLSTHLHHRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVESLSPELRGQLQALLLQRPQHYNQTTGTRPCWGSTHPRKASDNEEAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGSSAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN
Protein: Defective in cullin neddylation protein (Q38A65)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ubiquitin-conjugating enzyme E2, putative
- Cullin, putative
- Cullin, putative
- Cullin, putative
- Ubiquitin, putative
- NEDD8-activating enzyme E1 catalytic subunit
- Cullin 1, putative
- COP9 signalosome complex subunit 5
- TATA-binding protein interacting
Sequence:
MSWRVSCKTALLDELFTYIAGKTDANTLQKECVLALPQLETLAKMLGFSLDDMSMYRLAWSWSCEAPLCIRKSEFVNGMNAICSGVKLSATATSSTCSASPVKSPKKEFEPILLALRNHVETLDGALRGDVTKFRHFYRFIYKWVQSPLTMERNMGQVGMSIETAVELWRMLFPHYREFKRLDDWITFCMSKKLFPHGIISRDLWEQLLEFTFVTDYSKYDVSDAWPSAMDDFVEYVKSKV
Protein: Redox-sensing transcriptional repressor Rex (Q9X2V5)
Organism: Thermus aquaticus
Function: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01131}.
Interaction partners:
Sequence:
MKVPEAAISRLITYLRILEELEAQGVHRTSSEQLGELAQVTAFQVRKDLSYFGSYGTRGVGYTVPVLKRELRHILGLNRKWGLCIVGMGRLGSALADYPGFGESFELRGFFDVDPEKVGRPVRGGVIEHVDLLPQRVPGRIEIALLTVPREAAQKAADLLVAAGIKGILNFAPVVLEVPKEVAVENVDFLAGLTRLSFAILNPKWREEMMG
Protein: Mammalian ependymin-related protein 1 (MERP-1) (Q99M71)
Organism: Mus musculus (Mouse)
Function: Binds anionic lipids and gangliosides at acidic pH.
Subcellular location: Lysosome lumen {ECO:0000269|PubMed:16954209}. Secreted {ECO:0000250|UniProtKB:Q9UM22}. Note=Lysosomal and also secreted. {ECO:0000250|UniProtKB:Q9UM22}.
Interaction partners:
Sequence:
MPARAPRRLVQGPRGTWLLGSLWVWVLCGLGMAGSLGTPQPCQAPQQWEGRQVLYQQSSGHNNRALVSYDGLNQRVRVLDERKALIPCKRLFEYILLYKEGVMFQIEQATKQCAKIPLVESWDPLDIPQNSTFEDQYSIGGPQEQILVQEWSDRRTARSYETWIGVYTAKDCYPVQETFIRNYTVVMSTRFFDVQLGIKDPSVFTPPSTCQAAQPEKMSDGCSL
Protein: Protease-associated domain-containing protein 1 (Protease-associated domain-containing protein of 21 kDa) (hPAP21) (Q9BSG0)
Organism: Homo sapiens (Human)
Function: Plays a role in the modulation of physical activity and adiposity.
Subcellular location: Secreted {ECO:0000269|PubMed:15498570}.
Interaction partners:
Sequence:
MVPGAAGWCCLVLWLPACVAAHGFRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFW
Protein: Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem) (Q92785)
Organism: Homo sapiens (Human)
Function: Plays an active role in transcriptional regulation by binding modified histones H3 and H4. Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells. Might also have a role in the development and maturation of lymphoid cells (By similarity). Involved in the regulation of non-canonical NF-kappa-B pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:28533407, ECO:0000269|PubMed:29429572}. Cytoplasm {ECO:0000269|PubMed:28533407}.
Interaction partners:
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- AT-rich interactive domain-containing protein 1A
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
- AT-rich interactive domain-containing protein 1B
- SWI/SNF complex subunit SMARCC2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
- SWI/SNF complex subunit SMARCC1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
Sequence:
MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKRHRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLEALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIYQNQNSS
Protein: Gag-Pol polyprotein (Q8UN00)
Organism: Moloney murine leukemia virus (strain neuropathogenic variant ts1-92b) (MoMLV)
Subcellular location: Host cell membrane {ECO:0000256|ARBA:ARBA00004425}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004425}. Host cytoplasm {ECO:0000256|ARBA:ARBA00004192}. Host endosome, host multivesicular body {ECO:0000256|ARBA:ARBA00004560}. Host late endosome membrane {ECO:0000256|ARBA:ARBA00004566}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004566}. Virion {ECO:0000256|ARBA:ARBA00004328}.
Interaction partners:
Sequence:
MGQTVTTPLSLTLDHWKDVERIAHNQSVDVKKRRWVTFCSAEWPTFNVGWPRDGTFNRDLITQVKIKVFSPGPHGHPDQVPYIVTWEALAFDPPPWAKPFVHPKPPPPLPPSAPSLPLEPPLSTPSRSSLYPALTPSLGAKPKPQVLSDSEGPLIDLLTEDPPPYRDPRPPPSDGDGNSGEATPAGEAPDPSPMASRLRGRREPPVADSTTSQAFPLRTGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGDDGRPTQLPNEVDAAFPLERPDWEYTTQAGRNHLVQYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVAMSFIWQSAPDIGRKLERLEDLKNKTLGDLVREAERIFNKRETPEEREERIRRETEEKEERRRTEDEQKEKERDRRRHREMSKLLATVVSGQRQDRQGGERRRSQLDRDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLDDQGGQGQEPPPEPRITLKVGGQPVTFLVDTGAQHSVLTQNPGSLSGKSAWVQGATGGKRYRWTTDRKVHLATGKVTHSFLHVPDCPYPLLGRDLLTKLKAQIHFEGSGAQVMGPMGQPLQVLTLNIEDEYRLHETSKEPDVSLGSTWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGDLGYRASAKKAQICQKQVKYLGYLLKEGQRWLTEARKETVMGQPTPKTPRQLREFLGTAGFCRLWIPGFAEMAAPLYPLTKTGTLFDWGPDQQKAYQEIKQALLTAPALGLPDLTKPFELFVDEKQGYAKGVLTQKLGPWRRPVAYLSKKLDPVAAGWPPCLRMVAAIAVLTKDAGKLTMGQPLVILAPHAVEALVKQPPDRWLSNARMTHYQALLLDTDRVQFGPVVALNPATLLPLPEEGLQHNCLDILAEAHGTRPDLTDQPLPDADHTWYTDGSSFLQEGQRKAGAAVTTETEVIWAKALPAGTSAQRAELIALTQALKMAEGKKLNVYTDSRYAFATAHIHGEIYRRRGLLTSEGKEIKNKGEILALLKALFLPKRLSIIHCPGHQKGHSAEARGNRMADQAARKAAITETPDTSTLLIEKSSPYTSEHFHYTVTDIKDLTKLGAIYDKTKKYWVYQGKPVMPDQFTFELLDFLHQLTHLSFSKTKALLERSHSPYYMLNRDRTLKNITETCKACAQVNASKSAVKQGTRVRGHRPGTYWEIDFTEIKPGLYGYKYLLVFIDTFSGWIEAFPTKKETAKVVTKKLLEEIFPRFGMPQVLGTDNGPAFVSKVSQTVADLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLTLATGSRDWVLLLPLALYRARNTPGPHGLTPYEILYGAPPPLVNFPDPDMTRVTNSPSLQAHLQALYLVQHEVWRPLAAAYQEQLDRPVVPHPYRVGDTVWVRRHQTKNLEPRWKGPYTVLLTTPTALKVDGIAAWIHAAHVKAADPGGGPSSRLTWRVQRSQNPLKIRLTREAP
Protein: Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein (A0A384L363)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MRGALLRNASLCARRIILSPRITHQISPNVPFLAPIAAPAAPKFRFFSSESGENSTTAPESSPTDSPEKKDLVVEDVSNKELKSRIEKYFNEGNEDALPGVIEALLQRRLVDKHAETDDELLEKIESLPFKDDVKDEDFESDFEEAHSTDEELEDLYNSPEYVAEKMRKNEFFNMDDKKWDHMIREGIQHGCLTDTKECEEILEDMLKWDQLLPDDLKKKVEAKFNELGDMCERGEIEAEAAYELFKEFEDEMVIQYGDQMEAEGPPQFGETDASDRNTDLDDPPGKGPILRWQSRIVFAPGGDAWHPKNRKVKMSVTVKELGLSKHQAKRLRELVGKRYHSGKDELTITSERFEHREENRKDCLRTLYGLIEEAGKANKIAEDIRTSYVKQRLRANPAFMQKLQAKIIRSKESDAINA