wanglab/gogpt-training-data huggingface dataset:
Protein: Nucleoprotein (Nucleocapsid protein) (Protein N) (P27588)
Organism: Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980))
Function: Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
Subcellular location: Virion. Host cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MDLHSLLELGTKPTAPHVRNKKVILFDTNHQVSICNQIIDAINSGIDLGDLLEGGLLTLCVEHYYNSDKDKFNTSPVAKYLRDAGYEFDVIKNADATRFLDVSPNEPHYSPLILALKTLESTESQRGRIGLFLSFCSLFLPKLVVGDRASIEKALRQVTVHQEQGIVTYPNHWLTTGHMKVIFGILRSSFILKFVLIHQGVNLVTGHDAYDSIISNSVGQTRFSGLLIVKTVLEFILQKTDSGVTLHPLVRTSKVKNEVASFKQALSNLARHGEYAPFARVLNLSGINNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAAHDAEVKLQRRHEHQEIQAIAEDDEERKILEQFHLQKTEITHSQTLAVLSQKREKLARLAAEIENNIVEDQGFKQSQNRVSQSFLNDPTPVEVTVQARPMNRPTALPPPVDDKIEHESTEDSSSSSSFVDLNDPFALLNEDEDTLDDSVMIPGTTSREFQGIPEPPRQSQDLNNSQGKQEDESTNRIKKQFLRYQELPPVQEDDESEYTTDSQESIDQPGSDNEQGVDLPPPPLYAQEKRQDPIQHPAANPQDPFGSIGDVNGDILEPIRSPSSPSAPQEDTRMREAYELSPDFTNDEDNQQNWPQRVVTKKGRTFLYPNDLLQTNPPESLITALVEEYQNPVSAKELQADWPDMSFDERRHVAMNL
Protein: Abscisic acid 8'-hydroxylase 2 (ABA 8'-hydroxylase 2) (EC 1.14.14.137) (Cytochrome P450 707A2) (O81077)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the oxidative degradation of abscisic acid, but not in the isomerization of the produced 8'-hydroxyabscisic acid (8'-OH-ABA) to (-)-phaseic acid (PA). Involved in the control of seed dormancy and germination.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Abscisic-aldehyde oxidase
- Beta-D-glucopyranosyl abscisate beta-glucosidase
- 9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic
- 9-cis-epoxycarotenoid dioxygenase NCED9, chloroplastic
- Zeaxanthin epoxidase, chloroplastic
- Xanthoxin dehydrogenase
- Ethylene-responsive transcription factor ABI4
- Gibberellin 3-beta-dioxygenase 2
- Gibberellin 3-beta-dioxygenase 1
- Protein DELAY OF GERMINATION 1
Sequence:
MQISSSSSSNFFSSLYADEPALITLTIVVVVVVLLFKWWLHWKEQRLRLPPGSMGLPYIGETLRLYTENPNSFFATRQNKYGDIFKTHILGCPCVMISSPEAARMVLVSKAHLFKPTYPPSKERMIGPEALFFHQGPYHSTLKRLVQSSFMPSALRPTVSHIELLVLQTLSSWTSQKSINTLEYMKRYAFDVAIMSAFGDKEEPTTIDVIKLLYQRLERGYNSMPLDLPGTLFHKSMKARIELSEELRKVIEKRRENGREEGGLLGVLLGAKDQKRNGLSDSQIADNIIGVIFAATDTTASVLTWLLKYLHDHPNLLQEVSREQFSIRQKIKKENRRISWEDTRKMPLTTRVIQETLRAASVLSFTFREAVQDVEYDGYLIPKGWKVLPLFRRIHHSSEFFPDPEKFDPSRFEVAPKPYTYMPFGNGVHSCPGSELAKLEMLILLHHLTTSFRWEVIGDEEGIQYGPFPVPKKGLPIRVTPI
Protein: Histone H2B.1 (Q6CK60)
Organism: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000305|PubMed:32004465}. Chromosome {ECO:0000305|PubMed:32004465}.
Interaction partners:
- Histone H2A
- Histone H3
- Histone H4
- Histone H2A.Z
- Histone H3-like centromeric protein CSE4
- Histone-lysine N-methyltransferase, H3 lysine-4 specific
- KLLA0E01915p
- KLLA0F01925p
- FACT complex subunit SPT16
- KLLA0F22990p
Sequence:
MSAKASKAPASKAPAEKKPAAKKTSSSTDPSKKRTKARKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATESSKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA
Protein: Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog) (Q7L592)
Organism: Homo sapiens (Human)
Function: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:20406883, ECO:0000269|PubMed:24089531, ECO:0000269|PubMed:24838397, ECO:0000269|PubMed:28837730}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Arginine-hydroxylase NDUFAF5, mitochondrial
- NADH dehydrogenase complex I, assembly factor 6
- ATP synthase F
- Complex I assembly factor TMEM126B, mitochondrial
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- Complex I intermediate-associated protein 30, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Iron-sulfur cluster transfer protein NUBPL
- NADH dehydrogenase 1 alpha subcomplex assembly factor 2
Sequence:
MSVLLRSGLGPLCAVARAAIPFIWRGKYFSSGNEPAENPVTPMLRHLMYKIKSTGPITVAEYMKEVLTNPAKGYYVYRDMLGEKGDFITSPEISQIFGELLGIWFISEWMATGKSTAFQLVELGPGRGTLVGDILRVFTQLGSVLKNCDISVHLVEVSQKLSEIQALTLTKEKVPLERNAGSPVYMKGVTKSGIPISWYRDLHDVPKGYSFYLAHEFFDVLPVHKFQKTPQGWREVFVDIDPQVSDKLRFVLAPSATPAEAFIQHDETRDHVEVCPDAGVIIEELSQRIALTGGAALVADYGHDGTKTDTFRGFCDHKLHDVLIAPGTADLTADVDFSYLRRMAQGKVASLGPIKQHTFLKNMGIDVRLKVLLDKSNEPSVRQQLLQGYDMLMNPKKMGERFNFFALLPHQRLQGGRYQRNARQSKPFASVVAGFSELAWQ
Protein: Erythrocyte membrane protein 1, PfEMP1 (Q8I520)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Transcriptional coactivator ADA2
- PI3K/PI4K catalytic domain-containing protein
- Histone H4
- SANT domain-containing protein
Sequence:
MAPSTTYSSAKNAKELLDMIGKDVYNEKVKSEAQTYKEALKGDLNTANGYNSETRGTTDPCRLVEDYRSKAIGDANSERHPCGIGKDAKGEEVPRFSDTLGGQCTDHRIKGNNRNVTGGACAPLRRLHVCNKNMEKMDSTKIKDKNVLLAEVCYAAKYEGKSLVEKYKEYKQPNNDSDTDICTALARSFADIGDIVRGKDLYLGYDDEEKKQRDELEENLKTIFKNIYGNLDKKDRYEGDTKNYYQLREDWWYANRRQVWKAITCDAKAFNYFRNTCNGESPTKGYCRCNDDQPNADKPNTDPPTYFDYVPQYLRWFEEWAEDFCRKKNKKLNDVKKQCRGDNGTDRYCSGNGYDCTKTIRAIGKYAIGDECTKCSFWCRMYETWIDNQKKEFLKQKRKYDKEIEKYKNGTSNGTTTTKKTSNGPINNFYVKEFYEKLKGGYEKVDDFLELLNNEKECKGINEQEEKINFKTADISLNKNKNDEGTFYHSEYCKPCPHCGMKKKDGKWITKADDDKCNIKLYKPKKGATSTEIKILKSGDEPTEIGKKLKDFCTKTQNGTGGGGGGSGGNSEKKELYDEWKCYEFKHLDKVEEGEDDEVYEKDVKNGGGLCILKKEEEEKKEVKKTNSEKEPKEIQKTFHDFFYFWIRRFLNDSMYWRGKVNSCINKSKREKCKEECKKECECFQKWIDKKEKEWGQIKIHFNTQDFGSKGGLLGGVMTADFVLKTVLNIEDLFKDIKDGYGNAKELKGIENMLEKEKQKNKEEEAGASGGEDNTTIDKLLQHEGDEAGECLDTHKETCPDEGLGRTAAGYRPPSVTKGGDEEEELSTDEEEEEDEDDTEESPQAEPEEAESEDPDGESSTAETTQQEAVAPTTQDNAEKPCDIVDKLFQNPEQFKEVACKQKYAKNNSRLGWKCVTPSGDQKATSEGNGDANRRVARQTSESGEKSGDKDGAICIPPRRRRLYIQKLQEWAKTVGNTVVSGEPQTQGEASSPSDKESSQSDKLREAFIQSAAIETFFLWDRYKKEWALQKLAELQRNGDLPFFTSGAGYGMTAVVNGAQPTASPGHSNGLISLPSLVTDSDNPQNKLNDGTIPPDFLRQMFYTLGDYRDILFGDTTMIDTLKKSGDKDMLQREQNIKEAIDKILNSGNKEPSDEQRKTWWGDFAQYIWNGMICALTYTDSEKKDGKPQHNESVKKAFFGENNTDNPVTTSTQNGSPRLPTGTTGNTEGTYEKTYKYDIVKLDENSGTGDPLNNPKLKEFVEIPTFFRYLHEWGQNFCKERKKRLKQIKVDCRGDENTNRSNDGDGFNCEQIVPDKDVFWGDFIGSSCATSCSYYRKWINTKKAEYEKQEKIYVHQKAIAKNNKNDSAFSRTLDTYTTAGDFLENLKNGPCSKINSAEDNGNGNEEDKLNFRQPNVTFRPATDCKPCSLNELKCNSDVCGGNTKRKCDGKTDISAEDIETMGQPTEDIGMLVSDNSTTEIKDEGLKEACKDADIFKGIRKDEWKCGKFCDVDVCVLENFNKDIHDKKNVLIRTLFKRWLEYFLQDYIKINAKFSHCTNNGEGFACKNKCKDKCKCVEHWINQKRTQWGKIKERFFKQYNVTDSNDYNVRSFLQDLIPRIALTNDKKHFKTLDDLENIYGCNCAWKSGNREENDLVKCLLEKLKDKIGECNRFQTSANDCTTTPTAFEEDDDYIPLEEEEENQVVQPNICPAQTPAPTPAPAPAPAPAPAPAPAPAPAPAPSARPNHDQNPPGTGTRKITKRRQKSDKTKKTSNPTPSNVLDHPLMKPALMSSTIMWSVGIGFAAFTYFYLKKKTKSSVGNLFQILQIPKSDYGTPTPKSKNRYIPYVSDRYKGKTYIYMEGDSDSGHYYEDTTDVTSSESEYEELDINDIYVPRAPKYKTLIEVVLEPSGNNTTASGKNTPSDTQNDIQNDGIPSSKITDNEWNQLKDDFISNMLQSEQPNDIPNDYSSGTIPTNTNNTTPSHDNVDNNTHPTMSRLNVDQKPFITSIHDRDLYTGEEYNYNVNMSTNIMDDIPISGKNTVYSGIDLINDSLSGNQHIDIYDEMLKRKENELFGTNHVKQTSIHSVAKLTNSDPIHNQLELFHTWLDRHRDMCEKWENHHERLAKLKEEWENETHSGNTHPSDSNKTLNTDVSIQIHMDNPKTKNEFKNMDTTPNKSTMDTMLDDLEKYNEPYYYDFYKDDIYYDVNDDDKTSMDNNNNLVDKNNPVDSNNSTYNHRNPADINKNFVDKNNQNQHPIEKPTKIQIEMNSNNREVVEQQYPIADIWNI
Protein: LD38872p (Q960R6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRSSNDTITHIQAESGVKVQVMQDQDRVIMLRGQRDTVTKGREMIQNMANRAGGGQVEVLLTINMPPPGPSGYPPYQEIMIPGAKVGLVIGKGGDTIKQLQEKTGAKMIIIQDGPNQELIKPLRISGEAQKIEHAKQMVLDLIAQKDAQGQQQGGRGGGGGGGGPGMGFNNFNNGNGGESTEVFVPKIAVGVVIGKGGDMIRKIQTECGCKLQFIQGKNDEMGDRRCVIQGTRQQVDDAKRTIDGLIENVMQRNGMNRNGNGGGGGPGGDSGNSNYGYGYGVNHAQGGREEITFLVPASKCGIVIGRGGETIKLINQQSGAHTEMDRNASNPPNEKLFKSKGTTDQVEAARQMISEKINMELNVISRKPIGGGPGGGGGNSGGGQNNSHHNQQQGGYGGQNQMQGGDPNSGAGYQQQPWGGPYGQQGWDPSGQQQQMAMANQGGSAAGGASGGQDYSAQWIEYYKQMGCHREAEMIEQQMKAKQAGGSSGPVQQQQPQQQQQSQQQTGGAGAGGADYSAQWAEYYRSVGKIEEAEAIEKTLKNKQQNGSGGQSSTPNPSQGGSGQQQPNPAAAAAAAAAAAAAAGGYGQSMTPTQYAQYSQYYAAAAAAGGQPQGAPQPGGGQSGGPPGNYPGNYPGAGYGGYPGAPGQQQQKSHKNDNH
Protein: Sperm-specific dynein intermediate chain 1, isoform A (Q9W5W4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- GH16657p
- FI21737p1
- Cytoplasmic dynein 1 intermediate chain
- Sperm-specific dynein intermediate chain 2, isoform A
- Dynein light chain 2, cytoplasmic
- Dynein light chain 1, cytoplasmic
- Dynein light chain Tctex-type
- Dynein light chain roadblock
- Annexin B10
- Dynein light intermediate chain
Sequence:
MGLVLIKFLRSTYSTLSGGKKQPLNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAPAITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAGRVIERALSENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEQYIAWSPVRRQRPPGPDKTQPRHGAPALRRDSWTPSGLCIGDEAGKLYVYDVAENLAQPSRDEWSRFNTHLSEIKMNQGDEI
Protein: Prolyl 4-hydroxylase subunit alpha-3 (4-PH alpha-3) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3) (Q7Z4N8)
Organism: Homo sapiens (Human)
Function: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000305}.
Interaction partners:
- Protein disulfide-isomerase
- Collagen alpha-1
- Collagen alpha-6
- Collagen alpha-1
Sequence:
MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDTYEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED
Protein: GDNF family receptor alpha (Q98TT8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MDLNKATMIFATFWIMFPVLDLVHFSKADAIAQSRSVRLDCVRAHEQCLGKYGCSTKYRTMRQCVAGRTGNFSMKGEPEAQDECRNAIESMKQSPLYDCKCRRGMKKEKNCLRIFWSIYQSLQANDLLEDSPYEPVNSRLSDIFRLAPIISGEAAFTKDNNCLNAAKACNLNDTCKKYRSLYISPCTSRVSTTEVCNKRKCHKALRQFFDKVPPKHSYGMLFCSCPSGDHSACSERRRQTIVPACSYEDKEKPNCLSLQASCKTNYICRSRLADFLTNCQPEARSISGCLKENYADCLLAYSGLIGTVMTPNYLRAPGISVSPWCDCSNSGNGKAECDKFTEFFTNNRCLRNAIQAFGNGTDVGVWQPQPPIMSTPADPYTPPKGRDRTSNALDDPTLTNDLDSNADHLYSFCGSLQAQKLKSNVTLDVLCVDQQLNDPSSFNAITRSSTSAVCLVDWTVLLLLSLLSILHLDHLTASQTV
Protein: Protein KINESIN LIGHT CHAIN-RELATED 2 (Kinesin light chain-like protein 1) (AtKLC1) (Q9LII8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein DETOXIFICATION 34
- Subtilisin-like protease SBT3.1
- Kinesin-like protein KIN-7D, mitochondrial
- Pollen-specific leucine-rich repeat extensin-like protein 3
- AT4G01090 protein
- SBP family protein
- Anaphase-promoting complex subunit 8
- Conserved oligomeric Golgi complex subunit 2
- Protein RESPONSE TO LOW SULFUR 1
Sequence:
MDVGESNERVKDDSALQASPRSPLSSIDLAIDGAMNASIEQLYHNVCEMESSDDQSPSRASFISYGAESRIDLELRHLVGDVGEEGESKKEIILEKKEESNGEGSLSQKKPLSNGKKVAKTSPNNPKMPGSRISSRKSPDLGKVSVDEESPELGVVLLKQARELVSSGENLNKALDLALRAVKVFEKCGEGEKQLGLNLVMSLHILAAIYAGLGRYNDAVPVLERSIEIPMIEDGEDHALAKFAGCMQLGDMYGLMGQVENSIMLYTAGLEIQRQVLGESDARVGETCRYLAEAHVQAMQFEEASRLCQMALDIHKENGAAATASIEEAADRKLMGLICDAKGDYEVALEHYVLASMAMSSQNHREDVAAVDCSIGDAYMSLARFDEAIFAYQKALAVFKQGKGETHSSVALVYVRLADLYNKIGKTRDSKSYCENALKIYLKPTPGTPMEEVATGFIEISAIYQSMNELDQALKLLRRALKIYANAPGQQNTIAGIEAQMGVVTYMMGNYSESYDIFKSAISKFRNSGEKKTALFGIALNQMGLACVQRYAINEAADLFEEAKTILEKECGPYHPDTLAVYSNLAGTYDAMGRLDDAIEILEYVVGTREEKLGTANPEVEDEKQRLAALLKEAGRGRSKRNRALLTLLDNNPEIANGQRPVY
Protein: U11/U12 small nuclear ribonucleoprotein 65 kDa protein (U11/U12 snRNP 65 kDa protein) (U11/U12-65K) (Q8RWV8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of minor spliceosome required for U12-type intron splicing and alternative splicing of many introns. Binds specifically to U12 snRNA, which is necessary for branch-point site recognition. Required for normal plant development.
Subcellular location: Nucleus {ECO:0000269|PubMed:24606192}.
Interaction partners:
- Nuclear protein-like
- U1 small nuclear ribonucleoprotein C
- U2 small nuclear ribonucleoprotein A'
- U11/U12 small nuclear ribonucleoprotein 31 kDa protein
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein SmD3b
- Probable small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein SmD3a
- PHD finger-like domain-containing protein 5A
Sequence:
MAAHATSEPAVNLPATQFESQVTEPFGVTLLVRHLPDGIPHDIVSRLFSQYGASAVRPCSGGKLRNAAFVDFKNEAFASQAHRQLNGLRFLGKVLQVQRANKPNDNKKSRQIEESVTKGNAFSTVSTNNDSKSGQILSGEPIAPKLGIDYPFPPHLQYAYPPPDANILANITNALIAVPPLYTQVLHLMNKMNLPPPFRLALPTPPLPKAGPQQTDLEHQSSSESEMESDEDIGTSKSGRKRARHGFLVGLGMDKDVPHETVGVKPSSLTPKEIPRIRKNKHVMQIKITSKVTQDEYKEESENEDPADEPKEKDSNLKPFASLEELEKGRLPPQDILSLPMFKNYTAGNPSVVLYIKNLAKDVVIDDFYYIFGSQFESSEVAKSSLGVRLMQEGRMRGQAFLTFPSVEVAHRALNLVNGFVFKGKPMIIQFGRTPGAAKPNE
Protein: Polyprotein P1234 (Non-structural polyprotein) (A4L7I4)
Organism: Chikungunya virus (CHIKV)
Subcellular location: Host cell membrane {ECO:0000256|ARBA:ARBA00004112}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004112}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004112}. Host cell projection, host filopodium {ECO:0000256|ARBA:ARBA00004490}. Host cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004615}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004615}. Host cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004350}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004350}. Host nucleus {ECO:0000256|ARBA:ARBA00004147}.
Interaction partners:
Sequence:
MDSVYVDIDADSAFLKALQRAYPMFEVEPRQVTSNDHANARAFSHLAIKLIEQEIDPDSTILDIGSAPARRMMSDRKYHCVCPMRSAEDPERLANYARKLASAAGIVLDRNISGKIGDLQAVMAVPDTETPTFCLHTDVSCRQRADVAIYQDVYAVHAPTSLYHQAIKGVRVAYWVGFDTTPFMYNAMAGAYPSYSTNWADEQVLKAKNIGLCSTDLTEGRRGKLSIMRGKKLKPCDRVLFSVGSTLYPESRTLLKSWHLPSVFHLKGKLSFTCRCDTVVSCEGYVVKRITMSPGLYGKTTGYAVTHHADGFLLCKTTDTVDGERVSFSVCTYVPATICDQMTGILATEVTPEDAQKLLVGLNQRIVVNGRTQRNTNTMKNYLLPVVAQAFSKWAKECRKDMEDEKLLGVRERTLTCCCLWAFKKQKTHTVYKRPDTQSIQKVQAEFDSFVVPGLWSSGLSIPLRTRIKWLLRKVPKTDLIPYSGNAQEAQDAEKEAEEEREAELTHEALPPLQAAQEDVQVEIDVEQLEDRAGAGIIETPRGAIKVTAQLTDHVVGEYLVLSPQTVLRSQKLSLIHALAEQVKTCTHSGRAGRYAVEAYDGRVLVPSGYAISPEDFQSLSESATMVYNEREFVNRKLHHIAMHGPALNTDEESYELVRAERTEHEYVYDVDQRRCCKKEEAAGLVLVGDLTNPPYHEFAYEGLKIRPACPYKIAVIGVFGVPGSGKSAIIKNLVTRQDLVTSGKKENCQEISTDVMRQRGLEISARTVDSLLLNGCNRPVDVLYVDEAFACHSGTLLALIALVRPRQKVVLCGDPKQCGFFNMMQMKVNYNHNICTQVYHKSISRRCTLPVTAIVSSLHYEGKMRTTNEYNMPIVVDTTGSTKPDPGDLVLTCFRGWVKQLQIDYRGHEVMTAAASQGLTRKGVYAVRQKVNENPLYASTSEHVNVLLTRTEGKLVWKTLSGDPWIKTLQNPPKGNFKATIKEWEVEHASIMAGICSHQVTFDTFQNKANVCWAKSLVPILETAGIKLNDRQWSQIIQAFKEDKAYSPEVALNEICTRMYGVDLDSGLFSKPLVSVYYADNHWDNRPGGKMFGFNPEAASILERKYPFTKGKWNINKQICVTTRRIEDFNPTTNIIPVNRRLPHSLVAEHRPVKGERMEWLVNKINGHHVLLVSGYNLALPTKRVTWVAPLGVRGADYTYNLELGLPATLGRYDLVVINIHTPFRIHHYQQCVDHAMKLQMLGGDSLRLLKPGGSLLIRAYGYADRTSERVICVLGRKFRSSRALKPPCVTSNTEMFFLFSNFDNGRRNFTTHVMNNQLNAAFVGQATRAGCAPSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATPVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEKKISEAIQMRTQVELLDEHISIDCDVIRVHPDSSLAGRKGYSTTEGALYSYLEGTRFHQTAVDMAEIYTMWPKQTEANEQVCLYALGESIESIRQKCPVDDADASSPPKTVPCLCRYAMTPERVTRLRMNHVTNIIVCSSFPLPKYKIEGVQKVKCSKVMLFDHNVPSRVSPREYRSSQESVQEVSTTTSLTHSQFDLSADGETLPVPSDLDADAPALEPALDDGAVHTLPTIIGNLAAVSDWVMSTVPVAPPRRRRGRNLTVTCDEREGNITPMASVRFFRAELCPAVQETAETRDTAISLQAPPSTTMELSHPPISFGAPSETFPITFGDFDEGEIESLSSELLTFGDFLPGEVDDLTDSDWSTCPDTDDELXLDRAGGYIFSSDTGPGHLQQKSVRQSVLPVNTLEEVHEEKCYPPKLDELKEQLLLKKLQESASMANRSRYQSRKVENMKATIIQRLKRGCKLYLMAETPKVPTYRTIYPAPVYSPPINVRLSNPESAVAACNEFLARNYPTVSSYQITDEYDAYLDMVDGSESCLDRATFNPSKLRSYPKQHAYHAPSIRSAVPSPFQNTLQNVLAAATKRNCNVTQMRELPTLDSAVFNVECFKKFACNREYWEEFAASPIRITTENLTTYVTKLKGPKAAALFAKTHNLLPLQDVPMDRFTVDMKRDVKVTPGTKHTEERPKVQVIQAAEPLATAYLCGIHRELVRRLNAVLLPNVHTLFDMSAEDFDAIIAAHFKPGDAVLETDIASFDKSQDDSLALTALMLLEDLGVDHSLLDLIEAAFGEISSCHLPTGTRFKFGAMMKSGMFLTLFVNTLLNITIASRVLEDRLTKSACAAFIGDDNIIHGVVSDELMAARCATWMNMEVKIIDAVVSQKAPYFCGGFILHDTVTGTACRVADPLKRLFKLGKPLAAGDEQDEDRRRALADEVIRWQRTGLIDELEKAVYSRYEVQGISVAVMSMATFASSRSNFEKLRGPVITLYGGPK
Protein: Aspergillopepsin, putative (EC 3.4.23.-) (Q4WF96)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
Sequence:
MKFTSVLASGLLATAAIAAPLTEQRQARHARRLARTANRSSHPPYKPGTSEVIKLSNTTQVEYSSNWAGAVLIGTGYTAVTGEFVVPTPSVPSGGSSSKQYCASAWVGIDGDTCSSAILQTGVDFCIQGSSVSFDAWYEWYPDYAYDFSGISISAGDTIRVTVDATSKTAGTATVENVTKGKTVTHTFTGGVDGNLCEYNAEWIVEDFESNGSLVPFANFGTVTFTGAQATDGGSTVGPSGATLIDIQQSGKVLTSVSTSSSSVTVKYV
Protein: Ethylene-responsive transcription factor ERF036 (Q9LU18)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Stomatal closure-related actin-binding protein 2
Sequence:
MTSLNSSASPTSSSSDQSDATTTTSTHLSEEEAPPRNNNTRKRRRDSSSASSSSSMQHPVYRGVRMRSWGKWVSEIRQPRKKTRIWLGTFVTADMAARAHDVAALTIKGSSAVLNFPELASLFPRPASSSPHDIQTAAAEAAAMVVEEKLLEKDEAPEAPPSSESSYVAAESEDEERLEKIVELPNIEEGSYDESVTSRADLAYSEPFDCWVYPPVMDFYEEISEFNFVELWSFNH
Protein: Immunoglobulin heavy variable 2-5 (Ig heavy chain V-II region HE) (Ig heavy chain V-II region MCE) (P01817)
Organism: Homo sapiens (Human)
Function: V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Subcellular location: Secreted {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. Cell membrane {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}.
Interaction partners:
Sequence:
MDTLCSTLLLLTIPSWVLSQITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHR
Protein: Synembryn (Protein Ric-8) (F8VY51)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369048}.
Interaction partners:
Sequence:
MDEERALYIVRAGEAGAIERVLRDYSDKKLCEGIFKVLIKDIPTTCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQL
Protein: Lactosylceramide 4-alpha-galactosyltransferase (EC 2.4.1.228) (Alpha-1,4-N-acetylglucosaminyltransferase) (Alpha-1,4-galactosyltransferase) (Alpha4Gal-T1) (Globotriaosylceramide synthase) (Gb3 synthase) (UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase) (Q67BJ4)
Organism: Mus musculus (Mouse)
Function: Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer. Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
- Alpha-galactosidase A
- Beta-1,4-galactosyltransferase 6
- Beta-1,4-galactosyltransferase 4
- Beta-1,4-galactosyltransferase 1
- Beta-1,4-galactosyltransferase 3
- Beta-hexosaminidase subunit alpha
- Beta-1,4-galactosyltransferase 2
- Beta-hexosaminidase subunit beta
- Beta-galactosidase
Sequence:
MGISCSHLEETMSKPPDCLLRMLRGTPRQRVFTFFIISFKFMFLISILIYWHTVGAPKDQREYSLPVDFSCPQLAFPRVSAPGNIFFLETSDRTSPNFLFMCSVESAARAHPESQVVVLMKGLPRDTTAQPRNLGISLLSCFPNVWIRPLDLQELFEDTPLAAWYSEARHRWEPYQLPVLSDASRIALLWKFGGIYLDTDFIVLKNLLNLTNTLGIQSRYVLNGAFLAFERKHEFLALCLHDFVANYNGWIWGHQGPQLLTRVFKKWCSIQSLEKSHACRGVTALPPEAFYPIPWQNWKKYFEDISPEELTQLLNATYAVHVWNKKSQGTHLEATSKALLAQLHARYCPTTHRAMKMYL
Protein: Hydroxycarboxylate dehydrogenase A (EC 1.1.1.-) (2-oxobutanoate reductase) (2-oxoglutarate reductase) (P45579)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the NADPH-dependent reduction of 2-oxoglutarate and 2-oxobutanoate, leading to the respective 2-hydroxycarboxylate. Cannot use NADH instead of NADPH as a redox partner. Do not catalyze the reverse reactions.
Interaction partners:
- Methionine aminotransferase
- HTH-type transcriptional regulator MetR
- Cystathionine gamma-synthase
- Uncharacterized protein YibI
- 5,10-methylenetetrahydrofolate reductase
- Bifunctional aspartokinase/homoserine dehydrogenase 2
Sequence:
MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKRAIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTAKALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIILNAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALSDQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGTKVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRPVESIHYLPVTLTPDTLRAAFKKVESFKA
Protein: Transmembrane inner ear expressed protein isoform a (Transmembrane inner ear isoform b) (A2AVI6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MRRGRRRGKMAMEGPGNQPPSLVPLLMSVTAVLISHHFFNAAAQIPDPELLPTDPPKKPDPVTSETVVFWGLRLWQVVGIFSMFILAIIITLCCIFKCRIPRTKKEIEARHAQRLAAKKYANTLETVPPLNELTEVPGALVETSALLTVSEQVQAHASGQLPAVREEDEPANPGT