wanglab/gogpt-training-data huggingface dataset:
Protein: Translocating chain-associated membrane protein (Q9XXK7)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- J domain-containing protein
- Transmembrane protein 107
- Alpha-mannosidase
- Protein transport protein SEC23
- Saccharopine dehydrogenase
Sequence:
MVKPQGGSKASKKPQPPILSHEFIIQNHGDIMSCVVMVFIVGLMFPLTHSLSSLFIAPQYNGTYTVAVEQGQEREVHGYLSGILDLPAIFFYSVCWIVVHAVVQEYGLDKISKKTHLSKVSTFKFGESFHQMFFTVYSIAHAFYIVSERLEDFSEVKSFSVWLGYPTEHRVMSAAYKLYFIFQISYWIHQFPEFYLQKLKRDEIRQKSVQAILHIAFISIAYFFNFTRVGLALITLEYITQLIFHIARFAHFVGRKGLSDPAFKLFNGSFVLVRLGSIIIAVMTFWYGLRQAESPFVDISAGNFNTAVIRLNVLLAVVLLQLFLLYSFVVFHMGRFRESNAKKEKKKSAAAAAAVPKKEKKRQDSESDSKKKN
Protein: Translation initiation factor 2 subunit gamma (EC 3.6.5.3) (aIF2-gamma) (eIF-2-gamma) (Q980A5)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
Interaction partners:
- Translation initiation factor 2 subunit alpha
- Translation initiation factor 2 subunit beta
- Small ribosomal subunit protein eS6
- Translation initiation factor 1A
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein eL8
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS15
Sequence:
MAWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI
Protein: Kinesin-like protein (A0A494BYR6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSHPGVTTVMAVEDSTLQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPGIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLEPKGPLAIREDPDKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLSLKSNVTSLDCHISQYATICQQLQAEVAALRKKLQVYEGGGQPPPQDLPGSPKSGPPPEHLPSSPLPPHPPSQPCTPELPAGPRALQEESLGMEAQVERAMEGNSSDQEQSPEDEDEGPAEEVPTQMPEQNPTHALPESPRLTLQPKPVVGHFSARELDGDRSKQLALKVLCVAQRQYSLLQAANLLTPDMITEFETLQQLVQEEKIEPGAEALRTSGLARGAPLAQELCSESIPVPSPLCPEPPGYTGPVTRTMARRLSGPLHTLGIPPGPNCTPAQGSRWPMEKKRRRPSALEADSPMAPKRGTKRQRQSFLPCLRRGSLPDTQPSQGPSTPKGERASSPCHSPRVCPATVIKSRVPLGPSAMQNCSTPLALPTRDLNATFDLSEEPPSKPSFHECIGWDKIPQELSRLDQPFIPRAPVPLFTMKGPKPTSSLPGTSACKKKRVASSSVSHGRSRIARLPSSTLKRPAGPLVLPGDWH
Protein: Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (PEPCK-C) (EC 4.1.1.32) (Serine-protein kinase PCK1) (EC 2.7.11.-) (P07379)
Organism: Rattus norvegicus (Rat)
Function: Cytosolic phosphoenolpyruvate carboxykinase that catalyzes the reversible decarboxylation and phosphorylation of oxaloacetate (OAA) and acts as the rate-limiting enzyme in gluconeogenesis. Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate. Acts as a regulator of formation and maintenance of memory CD8(+) T-cells: up-regulated in these cells, where it generates phosphoenolpyruvate, via gluconeogenesis (By similarity). The resultant phosphoenolpyruvate flows to glycogen and pentose phosphate pathway, which is essential for memory CD8(+) T-cells homeostasis (By similarity). In addition to the phosphoenolpyruvate carboxykinase activity, also acts as a protein kinase when phosphorylated at Ser-90: phosphorylation at Ser-90 by AKT1 reduces the binding affinity to oxaloacetate and promotes an atypical serine protein kinase activity using GTP as donor (By similarity). The protein kinase activity regulates lipogenesis: upon phosphorylation at Ser-90, translocates to the endoplasmic reticulum and catalyzes phosphorylation of INSIG proteins (INSIG1 and INSIG2), thereby disrupting the interaction between INSIG proteins and SCAP and promoting nuclear translocation of SREBP proteins (SREBF1/SREBP1 or SREBF2/SREBP2) and subsequent transcription of downstream lipogenesis-related genes (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:4186849}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P35558}. Note=Phosphorylation at Ser-90 promotes translocation to the endoplasmic reticulum. {ECO:0000250|UniProtKB:P35558}.
Interaction partners:
- Pyruvate carboxylase, mitochondrial
- Pyruvate kinase PKLR
- ATP-citrate synthase
- Citrate synthase, mitochondrial
- Malate dehydrogenase, cytoplasmic
- Malate dehydrogenase, mitochondrial
- Alpha-enolase
- Gamma-enolase
- Pyruvate kinase PKM
- Beta-enolase
Sequence:
MPPQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM
Protein: Zinc finger protein 774 (Q6NX45)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MWLGTSGKSGLPGHCLENPLQECHPAQLEEWALKGISRPSVISQPEQKEEPWVLPLQNFEARKIPRESHTDCEHQVAKLNQDNSETAEQCGTSSERTNKDLSHTLSWGGNWEQGLELEGQHGTLPGEGQLESFSQERDLNKLLDGYVGEKPMCAECGKSFNQSSYLIRHLRTHTGERPYTCIECGKGFKQSSDLVTHRRTHTGEKPYQCKGCEKKFSDSSTLIKHQRTHTGERPYECPECGKTFGRKPHLIMHQRTHTGEKPYACLECHKSFSRSSNFITHQRTHTGVKPYRCNDCGESFSQSSDLIKHQRTHTGERPFKCPECGKGFRDSSHFVAHMSTHSGERPFSCPDCHKSFSQSSHLVTHQRTHTGERPFKCENCGKGFADSSALIKHQRIHTGERPYKCGECGKSFNQSSHFITHQRIHLGDRPYRCPECGKTFNQRSHFLTHQRTHTGEKPFHCSKCNKSFRQKAHLLCHQNTHLI
Protein: Mitochondrial import inner membrane translocase subunit TIM50 (Q580B0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU365079}; Single-pass membrane protein {ECO:0000256|RuleBase:RU365079}.
Interaction partners:
Sequence:
MSRKCRKRPSTTGSPSRYRGERRNRIAVRRQTRQSRSFRGDEPTSPVRSPQSSYVTIAGSAFSCSDDDESSELSDFDVINDVIQDALLESSDSSDYDDDDGNMSILQELRPFLFCSLYTVEDRRRRSRKEVTAPPVRRVSTRRSQGKRKGVLLPQGGGPPGAPLCFVVDLDETLVAARGGCAHLRPHLKELFDVCHEEGCEVVVWSAGTASHVNELVQAITTVVQRRAWYHHIISRHHRWFKEDCGGVKDLSLLGRPLDRVLCLENNPLSVHRQPRHSILVEDYVQPANSDDTLRFVAGVLRRIASRLRSAGERGGDVAQLLSVDSGLVELVIPINPQLSVTDPLVNNLYSIHSRGLRYSPQSVFTQRCYGGQRPFPASGS
Protein: Myelin gene expression factor 2 (Q9Y655)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MENDESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRRVNIKEDPDGENARRALQRTGTSFQGSHASDVGSGLVNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKAGSYKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSPDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGHRDIGLSRGFGDSFGRLGSAMIGGITGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA
Protein: Small ribosomal subunit protein mS29 (Q8IA36)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MIRNRFGSLSRVSAQLQRHVQQMSTNAAASPAEGATISEFRTAVSNPGEHSAMQVAKFYTIPAEQKKQIFTGGGLPKQYEQQIKTFTEACLMVRNPALELLQYIKDGDLTKPVVRYVLYGENGTGKTLTMAHVLHYGALNDFLLVHVPWAPNWMKRPKEASNAAGQEGMIDLPFDAAAWLVHFKTQNGPLLQRLQLKTSKEYVWSKRESTPAGSSLIELVEHGIARIKYASETTAALIAELKQLSTAGKCKVMVAIDGFNAFFHPVTRIFSDNKQLVTPDRVTLTQPFLDITNYDWTNGVCILSVDKIAMTEGHMDSYMPRYLLGKEGFEHLDPFVPIHVENYTDKEFHSYISYYLDRHWINKTPQGFEEQLKFMSNKNPYSLMQLVKAL
Protein: Ribosome-interacting GTPase 2 (GTP-binding protein RBG2) (P53295)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in ribosomal function.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Protein GIR2
- eIF-2-alpha kinase activator GCN1
- Translation machinery-associated protein 46
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS10A
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS13A
- Large ribosomal subunit protein uL15
- Small ribosomal subunit protein uS2A
- Small ribosomal subunit protein eS1A
Sequence:
MGIIDKIKAIEEEMARTQKNKATEHHLGLLKGKLARYRQQLLADEAGSGGGGGSGFEVAKSGDARVVLIGYPSVGKSSLLGKITTTKSEIAHYAFTTLTSVPGVLKYQGAEIQIVDLPGIIYGASQGKGRGRQVVATARTADLVLMVLDATKSEHQRASLEKELENVGIRLNKEKPNIYYKKKETGGVKVTFTSPPKTNLTEQAIKMILRDYRIHNAEVLVRDDQCTIDDFIDVINEQHRNYVKCLYVYNKIDAVSLEEVDKLAREPNTVVMSCEMDLGLQDVVEEIWYQLNLSRVYTKKRGVRPVFDDPLVVRNNSTIGDLCHGIHRDFKDKFKYALVWGSSAKHSPQKCGLNHRIDDEDVVSLFAK
Protein: Uga33p (A0A1D8PTY5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- NADH-ubiquinone oxidoreductase
- Uncharacterized protein
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH-ubiquinone oxidoreductase chain 4L
- NADH-ubiquinone oxidoreductase chain 2
- Probable sucrose utilization protein SUC1
- Znc1p
- Nuc2p
Sequence:
MSSQSPRFKRQRSKTGCKNCRLRKRKCDELHPTCTFCHTRDLICEYNEIKILNPTSFKPSKRIKKVQKNPSVSCSDLIPLTTDLHFPEPIFSPILNTNALSPLILYLDDQGIDYVRQFEQIASTLSLSQSTNYIKSTFLTLAFSNEAISNLLAAWGASHYGDSDDVNKYLMLAKGSIKNPHDRFDYFTTFACYLIQMAIYINTGDTQNWFQIFRKCETMIREYGGLIKFITDFQYSNDCKFLISNFQFYDVMSSESLERGTTCTMDKYLSLFKGRRILDETYGVDPYQGCCQPIYLLLGEIMNTYVELKKDRHNIVNCESVNVRVQYYKKVNEKVDHLIQSIDKCQPTPIPDGDGLQLKLFELCCIIGRMYVLLYIKQTQPKSSEIQLLLLDAISIIDELISTHLASNLSMALLMCGITCGNKYDRQNINGKFKIVYDKFRQGNLKRIWEIVKESWERNPLGNVCIDWLDICHDFNWKISMI
Protein: Natural resistance-associated macrophage protein 2 homolog (Q553K4)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Divalent transition metal (iron and manganese) transporter.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- P-type ATPase
- Frataxin, mitochondrial
Sequence:
MNNNNNNKKLNKENLNEIENWNEIELTDYKKQGLDEGTSSNIYLFESNGNVVNGSIEDSPKQQQQQQQQQQQQQQQQQQQQQQQQNIISSDEEIEDKPFQDRDSNIGDGSDIDSSGDSIDIENTDYSILVPFEDEENNNGSKSKFSIKKLKSFLGPALFISVGYMDPGNWATDLEGGSRFGYQLMWVLLFSNIMALFLQTLVIKLALVTKNDLAQQCRKEYSKTVNIFLWLILELAIISTDLAEVIGTAIGLNILFGLPLIAGVAITSLDTLLFLAIQRWGIRKLELLILLLLSMITMCFVIELFLSKPIASEVFSGFVPRLNSDSVMVATGIVGATTMPHNLFLHGSVVKSRKIPNDRRKSVIKQAYRYNVIDTVLALNCAFFVNIAILMLAASVFWKSNIQVTELSEAYRLLTKLMDGKLAAVLFGLGLFLAGQSSTITGTMAGQIVMEGFIKLRIKPWLRRFITRLLAIIPAAIVIIVLGDKGTYTLLIISQVLLSIGLPFAVVPLIIFTSSYEIMGEFKNRLSIIIINSIIALFIIGLNLATIFQLINDFLHNDSIISKCLTIIFLIPLSIALCCLLLWLIISKINFFTNLLSKIFNNNNNNNNKNIINNNNNYSGNTINNQTIQ
Protein: Transcription factor BHLH42 (Basic helix-loop-helix protein 42) (AcBHLH42) (A0A2R6QE26)
Organism: Actinidia chinensis var. chinensis (Chinese soft-hair kiwi)
Function: Transcription activator involved in the spatiotemporal regulation of anthocyanin biosynthesis specifically in the inner pericarp of red-fleshed kiwifruits. Functions in association with MYB123 to activate the promoters of LDOX (ANS) and F3GT1 that encode the dedicated enzymes for anthocyanin biosynthesis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:30912865}.
Interaction partners:
- Transcription factor MYB123
Sequence:
MAAPPSTRLQGMLQTAVQSVQWTYSLFWQLCPQQGILVWGDGYYNGAIKTRKTVLPIEVSAEEASLQRSQQLRELYDSLSAGESNQQTRRPCAALSPEDLTESEWFYLMCVSFSFPPGVGLPGKAYAKRQHVWLTGANEVDSKVFSRAILAKSARVQTVVCIPLLDGVVELGNTERVQEDIGFIHQVKSFFIDHHPPPPPKPALSEHSTSNLATSSVHPRFHSPPLPLTYAPLDPPLIANQIHMEEEQEQEQEEDEDDDDDDDDEEEAESDSEAHTGLNSEAQNPRVDHVARAAAEPSELMQLEMSEDIRLGSPDDGSNNMDPDFQLMVASQGGNPADQQQRVDSFRAESTRRWPLLQDPLGRSLQAPTSGGTGLEELTQDDTHYSQTVSTILQHQSNRWLESSSSSAAGCLMYSSQSSFSKWPLRPSDHHHQADATSQCLLKYILFTVPFLHSKYRDDNNSPKSATAADSASRFRKPTPQDELSANHVLAERRRREKLNERFIILRSLVPFVTKMDKASILGDTIEYVKQLRKNIQDLEARARQIEIDQRSRSSGDPQRSGAKAATDKRKLRIVEASGGAKGKAVDSVAVATPPPPAPPQPVAGVGVQVQVSIIESDALVELQCTHREGLLLDVMVVLRDHRVEVTAVQSSLTNGVFVAELRAKVKENVNGKKPSIVEVKRAIHQIIP
Protein: Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1) (Q9H422)
Organism: Homo sapiens (Human)
Function: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11034606}. Nucleus {ECO:0000269|PubMed:11034606}.
Interaction partners:
- Cellular tumor antigen p53
- Ras association domain-containing protein 5
- Serine/arginine-rich splicing factor 5
- FAS-associated death domain protein
- Heterogeneous nuclear ribonucleoprotein H
- Transformer-2 protein homolog beta
- DDB1- and CUL4-associated factor 7
Sequence:
MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGSAFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISCSNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEPGREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETSIRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGHDSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQPLIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM
Protein: Pms2 protein (B1H246)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- DNA mismatch repair protein Mlh1
- DNA mismatch repair protein
- DNA mismatch repair protein Msh2
- DNA mismatch repair protein
- Exonuclease 1
- DNA 5'-3' helicase
- Fanconi-associated nuclease
- DNA polymerase delta catalytic subunit
- MutS protein homolog 4
- Breast cancer type 2 susceptibility protein homolog
Sequence:
MEPTEGASTECAKAIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATSIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIREFADLTQVETFGFRGEALSSLCALSDVTISTCHVSASIGTRLVLDHNGKIIQKTPCPRPKGTTVSVQNLFYTLPVRHKEFQRNIKKEYAKMVQVLQAYCIISAGIRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLVPFVQLPPSDSVCEEYCLSACGTPQSPFRISGFISQCTHGAGRSSTDRQFFFINQRPCDPAKVSRLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLMGMFDSDANKLSVNQQPLLNVEGNLVKLHTAEVGEQENSPSLRITAEEKRVASVSRLREAYSLHRTTETKSWGPETPELKQSFPSQKRGVSSSCPSDIISYRGLCGSQDKLVSPTDSPGDCMDREKGEKDSGLSSTSAGSEEGFSTPEVASSFSSDCNVSSPEDRPSQENTNCGEQFLEVDDHLSGTGHHLKPEDNGYKCRASLPPTRLSPSNAKRFRTEDRPSNVGVPQNTSAAEVDVAVKINKKIVLLDFSLSSLAKQMKQLQHLKQQSKSEHNYRKFRAKICPGENQAAEDELRREIRKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALSASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN
Protein: Serine/threonine-rich protein adg2 (Meiotically up-regulated gene 46 protein) (O13854)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Secreted {ECO:0000305}. Endoplasmic reticulum {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Protein adg1
- Probable secreted beta-glucosidase adg3
- Glucan 1,3-beta-glucosidase 1
- Primary septum glucan endo-1,3-beta-D-glucosidase
- Glucan endo-1,3-alpha-glucosidase agn1
- Uncharacterized protein C306.11
- Chitin synthase regulatory factor 1
- Metallothionein expression activator
- SWIRM domain-containing protein laf2
- Septin ring organizing protein mid2
Sequence:
MRRLTISGLLISLAKLCAGMEINVPSSSDVWTSGHIEPLEWSVVSTDPLQANVWLINEVEYPPTSRYIMTINTFDENATFPALDLSPGYGYQISFTSIRDDSVIYAQSGTFYIVGGEGISSTTGSTFQSMTTFTSSQTNSGHASASTSIPSTAITVTANSTIYSSATSSFPYSTDVSVSTGTSTDIVTLPPPASSTSSFSTITNTSMIPSSSSFTTTTGSPYYNTSSFLPSSVISSASLSSSSVLPTSIITSTSTPVTVSSSSLSSFTPSYSTNLTTTGSTTTTGSATVSSSPFYSNSSVIPTSVPSSVSSFTSSSSSYTTTLTASNTSVTYTGTGTGSATFTSSPPFYSNSSVIPTSVPSSVSSFTSSNSSYTTTLTASNTSITYTGTGTGSATFTSSPPFYSNSSVIPTSVPSSVSSFTSSNSSYTTTLTASNTTVTFTGTGTGSATFTSSPPFYSNSSVIPTSAPSSVSSFTSSNSSYTTTLTASNTTVTFTGTGTGSATATSSSPYYSNSSIIVPTTVSTSGSVSSFSSSPSPTSSFSGTSALSSSSNEETTTTTQVTYTTSPEETTTTMTTTTCSSRPEETISTVSTTSTVSESGSSSASITSTYPSSTLSMTTSHLSSSSVHSSSAHSSSSRSSSMSLPPSAGSSTSLQRISLLCVFIPLLFLF
Protein: Probable histone-arginine methyltransferase 1.4 (AtPRMT14) (EC 2.1.1.319) (Coactivator-associated methyltransferase 1B) (Protein arginine N-methyltransferase 4A) (AtPRMT4A) (A3KPF2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation, methylates histone H3 and activates transcription via chromatin remodeling.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- SAP domain-containing protein
- Histone H3.1
- Histone H4
- Histone H3-like 4
- Histone H3-like 1
- Histone H3-like 3
- Histone H3-like 2
- Histone H3-like 5
- Histone H3.3
- Histone H3-like centromeric protein CENH3
Sequence:
MEIPSLNKQQEFTLASVTDLTSPSSSLSSSPVVATFSCVNEVKELRFQESKSSDGFSFDLSSTQLFKLGPLQFTCVSDGSISSAKEKSSFSRGVVIKFRDEKDSKEFCDSFEECKKDDAVKQGSALPNGTVVSANKSKFDDKIEAASAKMYFHYYGQLLHQQNMLQDYVRTGTYHAAVMENRSDFSGRVVVDVGAGSGILSMFAALAGAKHVYAVEASEMAEYARKLIAGNPLLAERITVIKGKIEDIELPEKADVLISEPMGTLLVNERMLETYVIARDRFLSPNGKMFPTVGRIHMAPFADEFLFVEMANKALFWQQQNYYGVDLTPLYVSAHQGYFSQPVVDAFDPRLLVAPSMFHVIDFTMMTEEQFYEIDIPLKFTASVCTRIHGLACWFDVLFDGSTVQRWFTTAPGAPTTHWYQIRCVLSQPIHVMAGQEITGRLHLIAHSAQSYTINLTLSAKMWGPGANQGGILQTSSCKLDLKEPYYRMSQPQVYPTQEPPAQSQDIHIHSDDLEELELLQQNANAQL
Protein: NADP-dependent mannitol dehydrogenase (MtDH) (EC 1.1.1.138) (Mannitol 2-dehydrogenase [NADP(+)]) (Q8NK50)
Organism: Hypocrea jecorina (strain ATCC 56765 / BCRC 32924 / NRRL 11460 / Rut C-30) (Trichoderma reesei)
Function: D-mannitol 2-dehydrogenase which is not necessary for D-mannitol catabolism. D-mannitol metabolism occurs via at least two different routes involving mannitol dehydrogenase (MDH) or mannitol 1-phosphate dehydrogenase, and the exact physiological role of mannitol dehydrogenases remains unclear.
Interaction partners:
Sequence:
MPQPVPTANRLLDLFSLKGKVVVVTGASGPRGMGIEAARGCAEMGADLAITYSSRKEGAEKNAEELTKEYGVKVKVYKVNQSDYNDVERFVNQVVSDFGKIDAFIANAGATANSGVVDGSASDWDHVIQVDLSGTAYCAKAVGAHFKKQGHGSLVITASMSGHVANYPQEQTSYNVAKAGCIHLARSLANEWRDFARVNSISPGYIDTGLSDFIDEKTQELWRSMIPMGRNGDAKELKGAYVYLVSDASSYTTGADIVIDGGYTTR
Protein: Glycine-rich RNA-binding protein 5, mitochondrial (AtGR-RBP5) (AtRBG5) (Mitochondrial RNA-binding protein 2b) (At-mRBP2b) (Organelle RRM domain-containing protein 4) (Q9C909)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possibly has a role in RNA transcription or processing during stress (By similarity). Binds RNAs and DNAs sequence with a preference to single-stranded nucleic acids. Displays strong affinity to poly(U) sequence. Involved in C-to-U editing of mitochondrial RNA. Functions as major mitochondrial editing factor. Controls 44 percent of the mitochondrial editing sites.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11972043, ECO:0000269|PubMed:26578708}.
Interaction partners:
- Zinc finger protein VAR3, chloroplastic
- Multiple organellar RNA editing factor 1, mitochondrial
- Protoporphyrinogen oxidase 1, chloroplastic
- Pentatricopeptide repeat-containing protein At5g13270
Sequence:
MAFLSKVGRLFSQTSSHVTASSSMLQSIRCMSSSKIFVGGISYSTDEFGLREAFSKYGEVVDAKIIVDRETGRSRGFAFVTFTSTEEASNAMQLDGQDLHGRRIRVNYATERGSGFGGRGFGGPGGGYGASDGGYGAPAGGYGGGAGGYGGNSSYSGNAGGGGGYGGNSSYGGNAGGYGGNPPYSGNAVGGGGGYGSNFGGGGGYGVAGGVGGSENFAQGSSTNAGFDDKFESNQPLGNDTDHQTESGLGGDEQFGGSDNQFGDAENGNTENGPVGFDQTDDGDVAKRA
Protein: Prunin 1 Pru du 6 (Pru 1 Pru du 6) (11S globulin) (11S seed storage protein) (Amandin Pru du 6) (Pru du amandin) (allergen Pru du 6) [Cleaved into: Prunin 1 Pru du 6 acidic chain; Prunin 1 Pru du 6 basic chain] (Q43607)
Organism: Prunus dulcis (Almond) (Amygdalus dulcis)
Function: Seed storage protein.
Interaction partners:
Sequence:
MAKAFVFSLCLLLVFNGCLAARQSQLSPQNQCQLNQLQAREPDNRIQAEAGQIETWNFNQGDFQCAGVAASRITIQRNGLHLPSYSNAPQLIYIVQGRGVLGAVFSGCPETFEESQQSSQQGRQQEQEQERQQQQQGEQGRQQGQQEQQQERQGRQQGRQQQEEGRQQEQQQGQQGRPQQQQQFRQLDRHQKTRRIREGDVVAIPAGVAYWSYNDGDQELVAVNLFHVSSDHNQLDQNPRKFYLAGNPENEFNQQGQSQPRQQGEQGRPGQHQQPFGRPRQQEQQGNGNNVFSGFNTQLLAQALNVNEETARNLQGQNDNRNQIIQVRGNLDFVQPPRGRQEREHEERQQEQLQQERQQQGEQLMANGLEETFCSLRLKENIGNPERADIFSPRAGRISTLNSHNLPILRFLRLSAERGFFYRNGIYSPHWNVNAHSVVYVIRGNARVQVVNENGDAILDQEVQQGQLFIVPQNHGVIQQAGNQGFEYFAFKTEENAFINTLAGRTSFLRALPDEVLANAYQISREQARQLKYNRQETIALSSSQQRRAVV
Protein: Uncharacterized protein C126.13c (O94405)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized RNA-binding protein C106.12c
- mRNA export protein mlo3
- RNA-binding protein with serine-rich domain 1 homolog
- Polyadenylate-binding protein 2
- Histone acetyltransferase type B subunit 2
- SWI/SNF chromatin-remodeling complex subunit sol1
- Pinin homolog 1
- FKBP12-associated protein 1 homolog
- Transcriptional regulatory protein sds3
- Histone deacetylase clr6
Sequence:
MDIRESRSQSPELSQSEDAVGPCPFLISVYHQFQTKNHVLDIFEDVIPSIQVYGWLTMTLYELGVLIADQLLLNNEETRHSEWSLQIRTIFYDKYKDRPIARDLGTVCLHNPKLFQGNKLLKRTGIKCGDKIDVTIKEDKIRIKK
Protein: Ribosomal protein L3, mitochondrial, putative (Q581Q1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- 60S ribosomal protein L39, putative
- 60S ribosomal protein L5, putative
- Ribosomal protein S19, putative
- 60S ribosomal protein L27a
- 60S ribosomal protein L13a, putative
- 60S ribosomal protein L17, putative
- 60S ribosomal protein L10, putative
- 60S ribosomal protein L7a
- 60S ribosomal protein L35A, putative
Sequence:
MSHCKFEHPRHGHLGFLPRKRSRQIRGRARSFPKDDPSQKPHLTSFMVYKAGMTHIVRDVDRPGSKVNKKEVVEPVTILEAPPMVVVGIVGYRQTPVGHKTIGTVWAHHTSVEFRRRFYKNWKQSAQLAFTKRKQFARTTEGRLAEARTLKAFEKKADIIRVVAHTQLRKLRNNRVGVKKAHVSEIQINGGTIAQKIELAKSLLEKEVRIDSVFQQSEACDVCAVTKGHGFTGVVKRWGVACLPRKTHRGLRKVACIGAWHPSRVMYTVARAGQHGYHHRTHLNKKIYQLGRAVSMEPNQATTAYDLTAKTITPMGGFVGYGTVRNDYVMLKGSVAGPRRRVITLRRPMAPQTSRKLTEKITLKFIDTSSKIGHGRFQTKKEKSQWYGPLKKDRIRREERLRKERAARAAERKAKGGATTTAAPRKSKK