wanglab/gogpt-training-data huggingface dataset:
Protein: Regulator of nonsense transcripts 1 homolog (EC 3.6.4.12) (EC 3.6.4.13) (Q9VYS3)
Organism: Drosophila melanogaster (Fruit fly)
Function: RNA-dependent helicase and ATPase required for nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an Upf1-Upf2-Upf3 surveillance complex is believed to activate NMD (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17178403}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000269|PubMed:17178403}.
Interaction partners:
- Serine/threonine-protein kinase Smg1
- LD36341p
- GH14566p
- Eukaryotic translation release factor 3, isoform A
- RE04053p
- FI21285p1
- 5'-3' exoribonuclease 1
- LD23870p
- Protein CASC3
- Polyadenylate-binding protein
Sequence:
MSVDTYAPSSALSFLDMDDNELLPGADTQPTQYDYRDFTMPSTSQSQTQNDQLEIAQRCSAGDSHPRLASITNDLADLQFEEEDDEPGSSYVKELPPHACKYCGIHDPATVVMCNNCRKWFCNGRGSTSGSHIINHLVRAKHREVTLHGEGPLGETILECYSCGVRNVFVLGFIPAKADSVVVLLCRQPCAAQNSLKDMNWDQEQWKPLIADRCFLAWLVKQPSEQGQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMKLMHGDELRLHYVGELYNPWSEIGHVIKVPDNFGDDVGLELKSSTNAPVKCTSNFTVDFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAGDGRLSRVKFTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQPERPMFFLVTQGQEEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLNNLKESLIHFQKPKKLVNSMNIGAHFMSTIIADAKEVMVPGSIYDRSGGYGQGRQMVGQSMNGGQYGGSGGGPYGNSPLGYGTPSSNSMVGFGLGNGGNGAAGGNNNFGGAGPSWAAAHLHHDSIGYISNEHGAAALGNMPVPVGMFMNMSNIPPRFYNQHQQAIMAVKQNRAIQQQTGNFSPGNSGPGVTGVGVGRSATPGGNKKTNKLGKSRVTGGGTGGAPLTQGSSVCNAAPYSQHPMPLSLQMTQPSGFALSQQPELSQDFGQISQMDGLLSQDVAFNASGERSLNQFSQPY
Protein: Large ribosomal subunit protein uL11 (50S ribosomal protein L11) (P0A7J7)
Organism: Escherichia coli (strain K12)
Function: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
Interaction partners:
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein bS6
- Large ribosomal subunit protein uL15
- Alternative ribosome-rescue factor A
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein bL33
- Small ribosomal subunit protein bS21
Sequence:
MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
Protein: Zinc finger MYND-type containing 11 (J3QKD2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKCETTTLFLNLW
Protein: Coatomer subunit zeta (Q38BH3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU366053}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|RuleBase:RU366053}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|RuleBase:RU366053}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|RuleBase:RU366053}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000256|RuleBase:RU366053}; Peripheral membrane protein {ECO:0000256|RuleBase:RU366053}; Cytoplasmic side {ECO:0000256|RuleBase:RU366053}.
Interaction partners:
- Coatomer subunit beta
- Coatomer subunit gamma
- Coatomer subunit delta
- Coatomer subunit alpha
- Coatomer subunit beta'
- Coatomer subunit epsilon
- ADP-ribosylation factor GTPase activating protein, putative
- ER lumen protein-retaining receptor
- SEC7 domain-containing protein
- Vesicle tethering protein Uso1/P115-like head domain-containing protein
Sequence:
MEYMHHIQGVVVLNDSGNRVFVKYYLNEDMKARGVLTTLEKQRALERVIYDAVSAPKRNWAASKDGDIVLHDVHSILFHVWGSITFAIVGDIKENEMVMHTVLRCIVDALQRILKTQDITHKGILEKYDALVLAVDEVIDDGIVLETSAQNVADDVAPFMADAETDTARSALSKVNEYLKENL
Protein: Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B) (Q9QZC4)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9Y5K3}. Cytoplasm {ECO:0000250|UniProtKB:Q9Y5K3}.
Interaction partners:
- Choline/ethanolaminephosphotransferase 1
- Cholinephosphotransferase 1
- Choline/ethanolamine kinase
- Choline kinase alpha
- Choline-phosphate cytidylyltransferase A
- Mitogen-activated protein kinase 10
- Phosphoethanolamine/phosphocholine phosphatase
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase 1
Sequence:
MPVVTTDAESETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADESSCQCQAPHEKLTIAQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPNKTSPPSSPKAASASISSMSEGDEDEK
Protein: HMG-Y-related protein A (ZmHMGA) (High mobility group A protein) (Q9FYS5)
Organism: Zea mays (Maize)
Function: Binds A/T-rich DNA (e.g. present in the storage gamma-zein gene promoter) with a highly dynamic distribution into the nucleus. Probably involved in endosperm development, during cells shift from a mitotic cycle to endoreduplication leading to massive synthesis of storage proteins (zeins) and starch.
Subcellular location: Nucleus, nucleolus {ECO:0000255|PROSITE-ProRule:PRU00837, ECO:0000269|PubMed:11278346, ECO:0000269|PubMed:19781672}. Note=Follows a highly dynamic speckled distribution pattern throughout the chromatin of interphase nuclei. {ECO:0000250|UniProtKB:Q43386}.
Interaction partners:
- C3H transcription factor
Sequence:
MATDEATKPSPIPPYPEMILAAIEGLDDKSGSNKSAISKYIEGKYGSLPPAHASLLTAHLARMKESGELVFLKNNYFRAGAPDAPPKRGRGRPPKARDPNAPAPAPKSPSSTGRGRGRPPKAKSPLEAAVKQATAGMPKPRGRPPKKAKTDGAASPSPSPAPAPAGDGSTPGKRGRGRPPKVRPAVPSETAAA
Protein: DDT domain-containing protein DDR4 (DDT-related protein 4) (F4IDY7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription regulator.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00063}.
Interaction partners:
- Ribosome biogenesis protein BOP1 homolog
- Homeobox-DDT domain protein RLT1
- Pescadillo homolog
- DDT domain-containing protein
- Ribosome biogenesis protein WDR12 homolog
- Homeobox-DDT domain protein RLT2
- AT5g04600/T32M21_200
- Uncharacterized protein At5g25580
- Zinc-finger domain of monoamine-oxidase A repressor R1 protein
- AT5G18310 protein
Sequence:
MGSSSDIVPDRSPADDVAPVTDTKIPKEEPLTLRRTRPSRACTVRAQQRLQELQAAERKLKPPKKEYKREQHRRREEVVEEDEDSEDDDQEDEENDGDDESNPKQCVAGGSSTKIITSLVPPPEPSQMPRWNLRSMWELASVLNFLHVFRPLLKINAEFSAEEFETALLTPNDTLSDIHIPLLKAIPPVTRMALTRDTWVTVLCRKIRDCWHWVAEGDLPIVALQGREIEVYKNLDPAIRVVILKALCDIRVEQEDIRSYIDNSLKTGVHLSVFRKDRVGGDSHGVNFWYEEDPLIGHRLYREIRKAEVLKVKTKGSKILPNITYQWETVATNFDEFQDVSEKLLQSSSRIEVSLGKKLVKDMLPEIEKEHKRKEKLLKKQHRQALLLDNFVVVDGLAGRSLRDRKPVRYTFDDYDKSINDAIKITKKKHPSPEHPLHRRESARLDALANGRSTSSTHPTEPVNDTASGRSSDFADYDDFDEHRDESLDRRRRQRPQRYSATDFVETVSDNEVEFQSDDDIYGEAVYDEEYLKKRKQKKLSSGSEGDEEKGDEEYKWDEDNAEYEEEEEEEEEEDSLSASEEDSDEPRRAKKMPRRETKLRSRSNDFRPGLRRSKRATRIDYQQYEFSDSDKEATGLAKRKRFVEPDEPSDETGNGDFTMGSQDSEENANDPETKSGEEEEPRDVNDNADTTNGKENNQLNKSNGTTDQEEVEGVVGKRRYLDLNELAPVSGFDDGPSTVLKDDDKTDNS
Protein: UDP-glucuronosyltransferase (EC 2.4.1.17) (A3KPS8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|RuleBase:RU362059}; Single-pass membrane protein {ECO:0000256|RuleBase:RU362059}.
Interaction partners:
Sequence:
MAPLFKNLCSVSLWITIIPLFGFLCDGGKILVVPLEGSHWLNMDILIKALHGKGHSIDVIRNTNSWYVKEKSDYYNSITIPQSKGMDEEFVDDMISKVINHERGKSSWLSTVKLFFDSVIDNYEMTKMVCDITTSIFESEEILKTLQEKQYDLMLTDPVWGMGIILAHKLKLPMVYNVRWTTTVDGHFNIAPSPMSYIPITGSGNTDRMSFFQRVKNIIFYFTNDIKYSRFSLPQYQAICDKYFDPPVDFYQLLQGADIWLMRVDFVFEFPRPTMPNIIYTGGFQCTPAKPLPHDLEDFMQSSGDHGVIVMSLGTFISALPEDVTAEIAAAFARLPQKVIWRYTGKKPSTLGNNTLLVDWMPQKDLLGHPKTKVFVAHGGTNGVQEALYHGVPVVGIPFFFDQYDNLIRLQARGGAKIVSLAELGENSLHAAIKEVINNPSYRLTMQKLSQLHLDKPVKPLDSAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVAVTLIAVVLIFIFSIFYVVRYVCIKCCSRKRKTE
Protein: Laminin subunit beta 1 (A0A8I5ZVQ5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
Interaction partners:
Sequence:
MERPLSSLPTFAFSPLYLSRKEDTKKRRAACLPRPPSRAASPRLQGLDMGVLQVFAFGVLALWGTRVCAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICDSRDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTVQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCESSFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSSSCHFDMAVFLATGNVSGGVCDNCQHNTMGRNCEQCKPFYFQHPERDIRDPNLCEPCTCDPAGSENGGICDGYTDFSVGLIAGQCRCKLHVEGERCDVCKEGFYDLSAEDPFGCKSCACNPLGTIPGGNPCDSETGYCYCKRLVTGQRCDQCLPQHWGLSNDLDGCRPCDCDLGGALNNSCSEDSGQCSCLPHMIGRQCNEVESGYYFTTLDHYIYEAEEANLGPGVVVVERRYIQDRIPSWTGPGFVRVPEGAYLEFFIDNIPHSMEYEILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTVPDDDNQVVSLSPGSRYVVLPRPVCFEKGMNYTVRLELPQYTASGSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGEVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALIHQAGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPNGCKPCDCHLQGSVSAFCDAVTGQCHCFQGIYARQCDRCLPGFWGFPSCQPCQCNGHAEDCDTVTGECLSCQDYTTGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDGCASGYFGNPSDFGGSCQPCQCHHNIDTTDPEACDKETGRCLKCLYHTEGDHCQFCQHGYYGDALRQDCRKCVCNYLGTVREHCNGSDCHCDKTTGQCSCLPNVIGQNCDRCAPHTWQLASGTGCEPCNCNAVHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIGELTNRTHKFLEKAKALKISGVIGPYRETVDSVEKKVNEIRDILAQSPAAEPLKNIGILFEEAEKLTKDVTEKMAQVEVKLSDTASRSNSTAGELDALQAEAGSLDKTVNELAEQLEFIKNSDIQGALDSITKYFQISLEAEKRVNASTTDPNSTVEQSALTRDRVEDLMLERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTHPGADCSESECGGPNCRTDEGEKKCGGPGCGGLVTVAHSAWQKAMDFDRDVLNALAEVEQLSKMVSEAKVRADEAKQNAQDVLLKTNATREKVDRSNEDLRNLIKQIRDFLTEDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVETLSQVEVILQQSAADIARAELLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLTNASQRISKLERNVEELKRKAAQNSGEADYIEKVVYSVKQSADEVKKVSKSL
Protein: A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (ADMP-2) (Aggrecanase-2) (Q9TT92)
Organism: Bos taurus (Bovine)
Function: Metalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that shows proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including ACAN, VCAN, BCAN and NCAN. Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs. Plays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its VCAN remodeling properties. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration. Participates in the development of brown adipose tissue and browning of white adipose tissue. Plays an important role for T-lymphocyte migration from draining lymph nodes following viral infection.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9UNA0}.
Interaction partners:
- Brevican core protein
- Aggrecan core protein
- Collagenase 3
- Stromelysin-1
- Collagen alpha-1
- Metalloproteinase inhibitor 3
- Interleukin-1 beta
- SRY-box transcription factor 9
- Interstitial collagenase
- Interleukin-6
Sequence:
HAAFTVAHEIGHLLGLSHDDSKFCEENFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQIPGPEELPGQTYDASQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPKNNGRYCTGK
Protein: Inactive hydroxysteroid dehydrogenase-like protein 1 (Q8BTX9)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
Sequence:
MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDFYSLVRLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSGAAPASFLHRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANLLNRSLRKEALSCQA
Protein: Serine/threonine/tyrosine-interacting-like protein 2 (Inactive dual specificity phosphatase 27) (F1QWM2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for myofiber maturation.
Subcellular location: Cytoplasm, myofibril, sarcomere {ECO:0000305|PubMed:24203884}.
Interaction partners:
- EF-hand domain family, member B
- Kelch-like protein 38
- Guanylate cyclase 1 soluble subunit alpha 2
- Zinc finger, FYVE domain-containing 9b.
Sequence:
MASSVEDQQLQQEEAESVKDVQSHYLRCPSPSFSMMSDRFSTVSDRFSVISGSEAESIFMEPIHLSSTIAAKKIISEELPPRPARVSSPPDSALEPAQQLMVEDLYSRVQELLDERSLYNTPCVLDIQRALLRDRLEAPLSPVDEVWPNVFIAEKSVAVNKGRLKRLGITHVLNAAHGTGVYTGPLFYSGMNIHYMGIEVDDFPDADISPHFRSCAEFLDDALLTHRGKVLVDSMMGVSRSAVLVAAYLMIFQNMSIMEALLEIRKKRAISPNEGFIKQLRQLNETLMEERDEDDDETLSQCSVIDARGRLEEQESVFGVKADSIMVEEEEDGGGSVISSVASSAAAAALRAGVQCGSQQPNMQQPADQPSLPGQTREDEDGDVDRMILEWQKRNEKYQSEDWWEAQLLCEDEDDGEDKTQRAVRPDDLESVTSEDVRMVKERIGRRPRRAASLAGSTSSCSSYVDLWKQRLQELEEQAAARHRLQDQDTSSETQQKKIDDDVQSILSDSSSMYNFCKKNKENLTPLERWKIKRIQFGWNKKENAENGEQSEAEPAAAPDLEDVNLTAYQTWKLKQQKKHGGEENKEEILQMSRGEDTATARRRQRREEVLERSRRNLQESQSVCGWETESALSSSIPLSAFCAGAFPSASVCGDDSMSVLSGRSSVLSGRSTRSLPPAVLETPAPPTPVLGPNGEQMVNIANIQNWIASVVNETLQQKQTEMLMGASVAPSRAGSVFSAGRGVDDDKSSVLSGLSASTGLSRSRAESVVSVGAKARSVLSAAGRAESVFSAGGASQLSCGSRKSKITTTSVPLYSLFQDQVNLHKLDTMEKEIKSDMRDKMASYEIKKITEDNKRSTLYKKKKPKEDDEDVDIAKSNGLEELEARTCEKPKPKRDYGRSGILNLPASANNPTSSIDEWLEHVRPPSSKPRVYDGDSGPIRMSRPAYEELQEPSGLDFTSRRSSVSVEVDEEEDYSFRFSSRNCADDDLDPELSYSSRRSPSFNGLSESTSFASRRSYSRYEDEERSSFQNHSIKQKSSVYEDSGRTAGSRRDEEEDEEISAFIAQIKQRARARVAEEMEDDEVLTAWRKQEESKSHDHK
Protein: Dementin, isoform D (Dementin, isoform E) (Dementin, isoform F) (RE27685p) (RE74788p) (Q9VI21)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MRHNSPVSRERASEAAAATQTAAATAGGATAHSAGGTAGGSAAATTTAGGATSGSGTASANTNSNSSASSSTVAAAQAAVYSGGNTVTGSLGSAGVVARGFRSHSPTHRRRSRERQRRTHGSDQGGLLAYSGLVGVNDMTDFLGPQQGGGGGGGGGGGGGGGGGSAGTGSGLEDSRLSGNEDYYSSFVSDEFDSSKKVHRRCHERSSSVQAIDRLNTKIQCTKESIRQEQTARDDNVNEYLKLAASADKQQLQRIKAVFEKKNQKSAHNISQLQKKLDNYTKRAKDLQNHQFQTKSQHRQPREVLRDVGQGLRNVGGNIRDGITGFSGSVMSKPREFAHLIKNKFGSADNINQMSEAELQGMQSANADVLGSERLQQVPGAGTSTGSGGGGQNNNTGGAGSGTGKFNSDNGSECSSVTSESIPGGSGKSQSGASQYHIVLKTLLTELAERKAENEKLKERIERLETGQKEFNNLTATLESERYRAEGLEEQINDLTELHQNEIENLKQTIADMEEKVQYQSDERLRDVNEVLENCQTRISKMEHMSQQQYVTVEGIDNSNARALVVKLINVVLTILQVVLLLVATAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQWPDVQDIGSGLVRHLKQSLVVK
Protein: PIH1 domain-containing protein 1 (Q38DW7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RuvB-like helicase
- RuvB-like helicase
- RNA polymerase II-associated protein 3
- Nucleolar RNA binding protein, putative
Sequence:
MTDTQKAGAALLQNPQFMEIFQRAMGGEENIKNIPPEGDPQREKWLADLQKKIQEESMKSAKAKLEEIHSDENGQWMYILPEPGFCVKCKVAGGGKVFVNVCKHERIAEPIPIDDDNEAEVKFRIPLSCGQARAESDKSGKPCKVYDVIVNPSTIHRCTQDHDFRCFVISLCIHWIQQKSEPTLNLQEYRNMSFRVKGTLEPQRIRLSTTPKVANALGDEIRLPANATAASPVTNVGGRSGTGKLVQEITDAPAPAAAPAPPPTVNSPSPPEEPKPSVMRVESEGIYDWSTHSKPTINPYFRETVPAAYLVELHIPTVTTIAEVDVRVSPKRIELLYVDCEDGVPFLTVPLGYPIDEELQDAKFVRKTRTLKLKLRVKLPDETSDLGTKPDVDAALLEEEEQRIERERREKELLEHKQKMERLREEEEKVMQERKSYVENLAAVQQGEIPPALKEEMDKLPPGQLTVMLHRLESKTRKGDSIDAMLEKFPDSIVGSICRYIRGKLGLEQRVTGNGCGREAQVHQKTVPQPSPATCDGTTGSSAAKAATTGELTATSASRIEYNFAKKSEKLFGVAFHNRYLFALD
Protein: At5g56840 (MYB transcription factor) (Myb-like transcription factor family protein) (Similarity to Myb-related transcription activator) (Q9FJS9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- At5g19440
- NAD
- Protein BRI1-5 ENHANCED 1
- Pentatricopeptide repeat-containing protein At1g06143
- Transcription factor bHLH106
Sequence:
MGRRCSHCGNVGHNSRTCSSYQTRVVRLFGVHLDTTSSSPPPPPPPSILAAAIKKSFSMDCLPACSSSSSSFAGYLSDGLAHKTPDRKKGVPWTAEEHRTFLIGLEKLGKGDWRGISRNFVVTKSPTQVASHAQKYFLRQTTTLHHKRRRTSLFDMVSAGNVEENSTTKRICNDHIGSSSKVVWKQGLLNPRLGYPDPKVSVSGSGNSGGLDLELKLASIQSPESNIRPISVT
Protein: Peroxidasin (EC 1.11.2.-) (Q9VZZ4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the two-electron oxidation of bromide by hydrogen peroxide and generates hypobromite as a reactive intermediate which mediates the formation of sulfilimine cross-links between methionine and hydroxylysine residues within an uncross-linked collagen IV NC1 hexamer. Plays a role in extracellular matrix consolidation, phagocytosis and defense.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Viking, isoform A
- Glutactin
- Hemolectin, isoform A
- tyrosinase
Sequence:
MRFMLLMLQLLGLLLLLAGGVQSVYCPAGCTCLERTVRCIRAKLSAVPKLPQDTQTLDLRFNHIEELPANAFSGLAQLTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRWHLDVQRQLVSISLTCAAPQMLQNQGFSSLGEHHFKCAKPQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMGALRSQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIELKELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRNNVDLAPGDRYVRIAFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYERTLVNIRKHVQEGDNLTMKSEEYEFRDLLSREHLHLVAELSGCMEHREMPNCTDMCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHAIPSVSSESWDGIDCKKSCEMAPPCYPIEVPPNDPRVRNRRCIDVVRSSAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFPRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNSPPAIFDSYIPQTYTKRSNRQKRDLGKENDEVATAESYDSPLESLYDVNEERVSGLEELIGSFQKELKKLHKKLRKLEDSCNSADSEPVAQVVQLAAAPPQLVSKPKRSHCVDDKGTTRLNNEVWSPDVCTKCNCFHGQVNCLRERCGEVSCPPGVDPLTPPEACCPHCPMVK
Protein: Pentacotripeptide-repeat region of PRORP domain-containing protein (Q38DD7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKLLRRGIVRIRNVAAFPIPPALLCARRGVTSTPVSMQNARSGHFRPFSSDDEAQLAAILTTKPRHVARYVRQSVLHSRRKITHFRNSVTFLMIALQSRLQRSEISPADASALVESLMKECVELRQGDMAHLLFRASIRFRKYGMPMHYPLVKHLFDSYRSDNARDLMKNMADELRGDETLRMLAVLSYQLSGKYEEGEKLLQEIPLEKIGTEDYCALLGTYGMTSQYRRIISLTNQLLNHREAANGSRFDFDAIFSAAIIAIRGDGDMLEEVTKQALDNRAQLSDQAIGTLMRARLQRCRTASDVYEAERLLREDLGVNMLGMAAQTAVIARCSEILSKGQKVSDEIMLQKVQLLDSAVDESVANDAIDNLEPSYLTSLIKGYGVLGRFDDMKRCFNRLKEAGALHDGRLYDEMLRWYAHAYNLKEVIALKEEMQEQHIYHTAYTYQHLFRVLDKYYPRMVEKYMNEMRSKGIQIEYYMYPTLLRVFGVLQDYSIVEQLYREIKGKVAAGDVQVFSPAVAVQLLKTYQHDTSRCEVIIQEAENYGLLANEAVQAEIVQYYSMNNRHEDLNALVSRIPYKSPDIYRVLLRDTSKHRNRQGFDALLKEMRERHVSVNERTFGEVITGLGHFNDLEGVKRYFHEALTSNAVRSPLFFAVAASAFARLGDAQAVDECWNDLLQSKVTITMPVYNKFLDLYMASNNVEMVQQILNTMMKLVPPNPVTATTVVDMLGKMGRLSEMECVLEEMSRSANAAPTQVTYHQAMNAYAKSGDVTKMEAMREKMKEEGFQENHITFNILFEGYGRAKRYERVKELVEERKSKQIAMEEFGYAVLLNIYSRAHMVEETTQIVEEMVSAGVPFTSRMLATLATSFSYIGDIPKVEHYVSLLLSHRDRRQRDVESVYLMYAKMRDTVKIQELLDSEKLPKTQFIYNVCVGAFARAGEHTKVASLLTQMEERGFTLSRNTSVTLSTLLLKAGKLELAQTVLKWKGCTPSGGREREGEEGEEIEIEDTTALGADDRAH
Protein: ATPase inhibitor, mitochondrial (ATP synthase F1 subunit epsilon) (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1) (Q03344)
Organism: Rattus norvegicus (Rat)
Function: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (By similarity). Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- ATP synthase F
- ATP synthase F
- ATP synthase F
- Borealin
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- Uncharacterized protein
Sequence:
MAGSALAVRARLGVWGMRVLQTRGFGSDSSESMDSGAGSIREAGGAFGKREKAEEDRYFREKTREQLAALKKHHEDEIDHHSKEIERLQKQIERHKKKIKYLKNSEH
Protein: RNA-binding protein KhpA (KH-domain protein A) (Q72DU1)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00088}.
Interaction partners:
- Small ribosomal subunit protein bS16
- RNA-binding protein KhpB
- Large ribosomal subunit protein bL19
- Ribosome maturation factor RimM
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein bL20
- Large ribosomal subunit protein bL17
- Ribonuclease G
- Small ribosomal subunit protein bS18
Sequence:
MLKELVEYIAKSLVDKPEDVQVTEVEGEQTSVLELKVAKEDLGKVIGKQGRTARAMRTILSAASTKARKRSVLEILE
Protein: Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (A0A3L7I3A5)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU368083}. Cytoplasmic vesicle {ECO:0000256|RuleBase:RU368083}. Membrane {ECO:0000256|RuleBase:RU368083}; Single-pass membrane protein {ECO:0000256|RuleBase:RU368083}. Nucleus envelope {ECO:0000256|RuleBase:RU368083}. Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004540, ECO:0000256|RuleBase:RU368083}. Nucleus outer membrane {ECO:0000256|RuleBase:RU368083}.
Interaction partners:
Sequence:
MQWSLGRRWAWIALFLAVAAVLTQAVWLWLGTQNFVFQQEEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
Protein: Putative uncharacterized protein YER076C (P40049)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
Sequence:
MTSGYYTVSFFYAILLLCACTRAEIYLTGGESQGLPSGFWQMDDDLAIAPVSMVEFYQTIGLTANGTVPESFNKRDATEYPNIISNITTQAANFTQHSLVEQLQNDVTAISISNAINVAVDGSVETPADLQYNRNQETGESTLCRAKFYGVEVRTWSRLYNRAVSSTTLTTNLNSYIAQWVAWAVHGSGDKKFCGSQEFTNIFFDGQEGWSLFVKTWSTNSSCDITASEGNLTCAVRVSVSSMHNHGKTAFCVTYSHGDSWRAELRVVANDAWSHYYPWSIDCPEVDKNNMAINDCFDQAQG