wanglab/gogpt-training-data huggingface dataset:
Protein: CCR4-associated factor 16 (P43569)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- CCR4-associated factor 4
- Protein CAF130
- General negative regulator of transcription subunit 3
- Protein CAF40
- CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4
- Nascent polypeptide-associated complex subunit beta-2
- General negative regulator of transcription subunit 1
- General negative regulator of transcription subunit 5
- General negative regulator of transcription subunit 2
- Poly
Sequence:
MVSQFAIEVRNLTYKFKESSDPSVVDINLQIPWNTRSLVVGANGAGKSTLLKLLSGKHLCLDGKILVNGLDPFSPLSMNQVDDDESVEDSTNYQTTTYLGTEWCHMSIINRDIGVLELLKSIGFDHFRERGERLVRILDIDVRWRMHRLSDGQKRRVQLAMGLLKPWRVLLLDEVTVDLDVIARARLLEFLKWETETRRCSVVYATHIFDGLAKWPNQVYHMKSGKIVDNLDYQKDVEFSEVVNAKVNGQVAFENDNNKVVISKVNSLHPLALEWLKRDNQIPDKEIGI
Protein: COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (MFH protein) (P97834)
Organism: Rattus norvegicus (Rat)
Function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 8
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 2
- COP9 signalosome subunit 7A
- COP9 signalosome subunit 7B
- Ubiquitin-like protein NEDD8
- DNA damage-binding protein 1
Sequence:
MQIDVDPQEDPQNAPDVNYVVENPTLDLEQYAASYSGLMRIERLQFIADRCPPLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRELQNAPDAIPESGVEPPPLDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGLAELAARKYKQAAKCFLLASFDHCDFPELLSPSNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHKMAAAFNTTVAALEDELTQVILEGLINARIDSHSKILYARDVDQRSTTFEKSLLMGKEFQRRAKAMILRAAVLRNQIHVKSPPREGSQGELTPANSQSRMSTNM
Protein: H-2 class II histocompatibility antigen, A-D beta chain (P01921)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MALQIPSLLLSAAVVVLMVLSSPRTEGGNSERHFVVQFKGECYYTNGTQRIRLVTRYIYNREEYVRYDSDVGEYRAVTELGRPDAEYWNSQPEILERTRAEVDTACRHNYEGPETSTSLRRLEQPNVAISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMTPHQGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ
Protein: Alternative prion protein (AltPrP) (F7VJQ1)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:21478263}; Single-pass membrane protein {ECO:0000269|PubMed:21478263}.
Interaction partners:
Sequence:
MEHWGQPIPGAGQPWRQPLPTSGRWWLGAASWWWLGAASWWWLGAAPWWWLGTASWWWLGSRRWHPQSVEQAE
Protein: Serine protease inhibitor Kazal-type 1 (Pancreatic secretory trypsin inhibitor) (Tumor-associated trypsin inhibitor) (TATI) (P00995)
Organism: Homo sapiens (Human)
Function: Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:7142173}.
Interaction partners:
- Serine protease 1
- Trypsin-2
- Serine protease 58
- Chymotrypsin-C
- Trypsin-3
- Serine peptidase inhibitor Kazal type 2
- Cystic fibrosis transmembrane conductance regulator
- Chymotrypsinogen B2
- Chymotrypsinogen B
- Enteropeptidase
Sequence:
MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC
Protein: Bifunctional IPC transferase and DIPP synthase [Includes: 1L-myo-inositol-1-phosphate cytidylyltransferase (IPCT) (EC 2.7.7.74); CDP-L-myo-inositol myo-inositolphosphotransferase (DIPP synthase) (EC 2.7.8.34) (Di-myo-inositol-1,3'-phosphate-1'-phosphate synthase)] (O29976)
Organism: Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Function: Involved in biosynthesis of di-myo-inositol phosphate (DIP), a widespread organic solute in microorganisms adapted to hot environments. Catalyzes the condensation of CTP and L-myo-inositol-1-phosphate into CDP-L-myo-inositol, as well as the biosynthesis of di-myo-inositol-1,3'-phosphate-1'-phosphate (DIPP) from CDP-L-myo-inositol and L-myo-inositol-1-phosphate. The cytidylyltransferase is absolutely specific for CTP and L-myo-inositol-1-P. The DIPP synthase uses only L-myoinositol-1-phosphate as an alcohol acceptor, but CDP-glycerol, as well as CDP-L-myo-inositol and CDP-D-myoinositol, are recognized as alcohol donors.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Myo-inositol-1-phosphate synthase
- Fructose-1,6-bisphosphatase/inositol-1-monophosphatase
Sequence:
MILPCESFNGVPSGCLIIEMNWYSVLKASTAIFFPEKYSSSTSSLSKRSPISAPMINVDGEYLKIFAGRIKLMKAVILAAGLGTRLGGVPKPLVRVGGCEIILRTMKLLSPHVSEFIIVASRYADDIDAFLKDKGFNYKIVRHDRPEKGNGYSLLVAKNHVEDRFILTMGDHVYSQQFIEKAVRGEGVIADREPRFVDIGEATKIRVEDGRVAKIGKDLREFDCVDTGFFVLDDSIFEHAEKLRDREEIPLSEIVKLARLPVTYVDGELWMDVDTKEDVRRANRALVSAAVKGSGDGFISRKINRKISTRISAAIVNKVNPNQMTLISFLVGAFSALASFFSIPLAGLLYQFSSILDGCDGEIARASLKMSKKGGYVDSILDRFVDFLFLAIIALLYPKTATVAMFAIFGSVMVSYTSEKYKAEFGESIFGKFRVLNYIPGKRDERIFLIMIFCLLSAISLQWIFWMFLFVAAISLTRVVVTLLAVLVSK
Protein: Chaperone Ric-8B (Synembryn-B) (Synembryn-like) (Q6DRJ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
Subcellular location: Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q80XE1}. Note=Localizes to the cell cortex. {ECO:0000250|UniProtKB:Q80XE1}.
Interaction partners:
- diphosphoinositol-polyphosphate diphosphatase
- Delta-1-pyrroline-5-carboxylate synthase
Sequence:
MSLSDILSEIDGGDDKKVEKLLLKYNTENSRTFAFDLEEEGARIKLCQGLLTVLRRSDLPLCQSTCLETLRILSRDKHVLGPVATKEGMLTLAGLARICVAGHEGEPLEEAQSAEEERVVVEALKCLCNVVFNSVPAQQMGGDLQLAEGLCPRLHLVSASHHEVGLFSLRLLFLLSALRTDVRSTLQKEAGAVKLLTNVLERTLDVRWVGPYEAAPPDPEAPPIPPENNELTMEALKALFNLTMSDSCDKDSLHKLRLIAGIMRHLLMLKTHSEEKTEETHSHAINLLSNLPVQCLDVLIDVPVQGGLEKYRGKNMDTVQILLDFMIKRIDKGFNFKEGLTPVLSLLTESARYHREIRRYIKAQILPPLKDVKERPEIGDTIRNKLVRLMTHVDMAVKQGAAEFLFVLCKESVDNLLKYTGYGNAAGLLMARGLLAGGRGETQYSSDEDSDTEEYKSVKPFINPITGHVEDPLPNPLDEMTEEQKEYEAQRLVSMIDELSRKELIRPMGVRKDGTLAPLGQAIHDCSLASSGSDSD
Protein: E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18) (Q9NS91)
Organism: Homo sapiens (Human)
Function: E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:15632077, ECO:0000269|PubMed:22036607, ECO:0000269|PubMed:25931565}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15632077}. Note=Associates with chromatin (PubMed:25931565). Colocalizes with SLF1 in the nucleus and to centrosomes (PubMed:15632077). Relocalizes with SLF1 to nuclear foci in response to DNA damage (PubMed:22036607). Accumulates with the SLF1-SLF2 and SMC5-SMC6 complexes at replication-coupled DNA interstrand repair and DNA double-strand breaks (DSBs) sites on chromatin in a ubiquitin-dependent manner (PubMed:25931565). {ECO:0000269|PubMed:15632077, ECO:0000269|PubMed:22036607, ECO:0000269|PubMed:25931565}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 A
- Ubiquitin-conjugating enzyme E2 B
- Proliferating cell nuclear antigen
- Helicase-like transcription factor
- Polyubiquitin-C
- E3 ubiquitin-protein ligase SHPRH
- DNA repair protein RAD51 homolog 1
- Ubiquitin-conjugating enzyme E2 variant 2
- Ubiquitin-conjugating enzyme E2 N
- DNA repair protein RAD52 homolog
Sequence:
MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPVASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPDPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVREIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREEDSSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRAAESAEIEPRNKRNRN
Protein: NRAMP-like transporter smf-3 (DMT-1) (Divalent metal transporter smf-3) (Q95XG8)
Organism: Caenorhabditis elegans
Function: Probable divalent metal ion transporter which regulates the uptake of several heavy metals such as Mn(2+), Al(3+) and iron. Plays a role in modulating Al(3+)-induced dopamine (DA) neuron degeneration through the intracellular sequestration of Al(3+).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:19924247}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:19924247, ECO:0000269|PubMed:23106139}. Note=Translocates to apical cytoplasmic vesicles in intestine in response to high Mn(2+) levels (PubMed:19924247). In dopaminergic neurons, localizes to cytoplasmic vesicles (PubMed:23106139). {ECO:0000269|PubMed:19924247, ECO:0000269|PubMed:23106139}.
Interaction partners:
- NRAMP-like transporter smf-1
- NRAMP-like transporter smf-2
- Solute carrier family 40 member
- Solute carrier family 40 member
- Ferritin
- Ferritin
- Probable small nuclear ribonucleoprotein F
Sequence:
MEGEMKCPIEEIREKPEMRKAQQTYEVQVEVEDTPDTTFSWRKLWAFTGPGFLMSIAYLDPGNIESDLQAGAISYFKLIWVLLVAHIMGLLLQRLAARLGVVSGKHMAEIAFSYYPKIPRLVLWMLVESAIVGSDMQEVIGTAISFYLLSNGVIPLWAGVLITICDTFTFLFLEKYGVRKFEAFFCFLITCMAITFGYEFGVSAPDAGKMFSGMFVPWCNGCDNNMVMQGVAIIGAVIMPHNFYLHSALVKSRRVDRRRAEKVTEANKYFFIESAFALFVSFIINTLVISVFAQGMYGKTNQDIRDTCYNNTHNGMPDFYKVEFPANNDAAQSDIYHAGIFLGCTFGIFALYVWAVGILAAGQSSTMTGTYAGQFAMEGFIQIKLPQWKRILITRSLAILPTLAVVIFSGGIDNISSLNDFLNCLQLIQLPFALIPVLTFVSDRNIMHEYKLASVSKVVSIVISLIILFINFYFLYSWIGSTFGYNAVSIPITIFCAIFYIIFIAYLTYYCLVAMEFISPIQTKWLAEPIYHDFDAPWLEDSENPSTKNTISDDELSMRY
Protein: Large ribosomal subunit protein uL4c (50S ribosomal protein L4, chloroplastic) (CL4) (R-protein L4) (O50061)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This protein binds directly and specifically to 23S rRNA (By similarity). May play a role in plastid transcriptional regulation.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein bL9c
- Large ribosomal subunit protein uL15c
- Large ribosomal subunit protein bL27c
- Large ribosomal subunit protein uL24c
- Small ribosomal subunit protein uS9c
- Large ribosomal subunit protein uL6c
- Large ribosomal subunit protein bL21c
- Large ribosomal subunit protein uL13c
- Large ribosomal subunit protein uL3c
- Large ribosomal subunit protein bL28c
Sequence:
MASSATAPNSLSFFSSSLFLSSSHQIPKTYISVSKLGSGRVSKPLSVSSQLATLPILSFEGEKVGETYLDLKAAPEDTARAVVHRAIVTDLNNKRRGTASTLTRGEVRGGGIKPYSQKKTGHARRGSQRTPLRPGGGVVFGPRPKDWSIKINRKEKKLAISTALSSAASAEGGAIVVEEFGEKFEKPKTKDFLAAMQRWGLDPKEKAMFLMIDVDENVAKSSRNIGTLRMLTPRTLNLFDILNADKLVLTPAAVEFLNARYGVDAVEEEDDDEDETEGSEEA
Protein: 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase (EC 2.1.1.99) (16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase) (2,3-dihydrotabersonine N-methyltransferase) (CrDhtNMT) (CrNMT) (W5U2K2)
Organism: Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
Function: S-adenosyl-L-methionine-dependent N-methyltransferase that catalyzes a nitrogen methylation involved in vindoline biosynthesis. Displays a strict requirement for a 2,3-dihydro bond in the aspidosperma skeleton. Can use 2,3-dihydrotabersonine, 2,3-dihydro-3-hydroxytabersonine and 2,3,6,7-tetraydro-3-hydroxytabersonine as substrates, but not tabersonine, vincadifformine, picrinine, 21-hydroxycyclolochnericine, tryptamine, norharmane, harmaline, catharanthine, norajmaline, ajmaline, serpentine, ajmalicine, yohimbine or gamma-tocopherol.
Subcellular location: Thylakoid {ECO:0000269|PubMed:16665811}. Peroxisome {ECO:0000269|PubMed:35166361}.
Interaction partners:
Sequence:
MEEKQEKVAEFYDKVTGAWDLFYGVHLHDGYYEPGTTATMAISQDAVIRMIDELLRFAGVSEDPAKKPRSMLDVGSGLGGTCVYVAKKYDIQCTGITISPNQVKYAQDYAATEGVENKVSFDCGDALDMPYSDGKFDVVFTINCIEHVHDKEKFIREMVRVAAPGAAIIIASQAHPNLSPGESLKPRDKKILQKICDGAGAVSLCSSDDYVRWLTPLPVKEIKAADWTQNITPLYPLLMKEAFTWKGFTSIVLKGGWRAINLINAVRLVAKAANDGILKFAVVTGRKSI
Protein: Anoctamin (A0A8I6AA94)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU280814}.
Interaction partners:
Sequence:
MQMMTRNVLLNMELEEDDDEDGDIGDVPDSRRPFLAPHTPLPSGLVLENFDQTIVCSTFGSLESQEDFRTPEFEEFNGKPDSLFFTDGQRRIDFVLVYEDESKKENNKKGTNEKQKRKRQAYESNLISHGLQLEATRSVSDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKTRSTFDTFNWFTKVLRVNESVIKPEQEFFTAPFEKSRMNDFYILDRDSFFNPATRSRIVYFILSRVKYQVMNNVNKFGINRLVSSGIYKAAFPLHDCKFNYKSEDPNCPSERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCDPDIGGQILMCPQCDRLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQPRPEYEAQCNHVVINEITQEEERIPFTTCGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQMATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRYKRVSGSEKITPRWEQDYHLQPMGRLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKNTDKENPYIGLGNYTLCRYRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKITKSKIKREKYLTQKLLHESHLKDLTKNMGLIAERIGGVADSSVRPKLE
Protein: RNA-binding protein, putative (Q57WD2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA-binding protein, putative
- Pumilio/PUF RNA binding protein 5, putative
- CYC2-like cyclin
Sequence:
MMPCKSFPPSSKLLRHRSSELYSRDNLFMCNLSAAVDEAVLKQIFSPYGEILSAAVMRNIHTGDSLGTAFVRFATTEQARAALVGCHGRVVCGRVLSVQWAKRQHDGTPVGEARKKIVKLFIRNIPLDVGPEDVQRLFERFGTVESVSLHKDTAAATPTTDNSRPQRRIAFVTFTESGVADRAAEAVHNTRPFPSHGSVPLMVKLAEDHSERRLAAAAAVAGGGSGHNSSSFCVPQPRFVGRQQPKVLRPPSGERLPVQPLCVLGSKGSGPSPILRSPNIVAATRVDDFMDIAVGRWKMPEPLSTTINTCCTVMPQAPVGTNGKFFTVSGSGLCAASRSAISCSICESKKGMRYTHEPYRSVVCNPTGIPVPPSPVD
Protein: Uncharacterized protein (Q382E6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- NADH dehydrogenase 1 beta subcomplex subunit 8
- Uncharacterized protein
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH-ubiquinone oxidoreductase, mitochondrial, putative
- Uncharacterized protein
- NADH-ubiquinone oxidoreductase complex I subunit
- 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Complex 1 LYR protein domain-containing protein
Sequence:
MSVVGVSSYFLWTQKGNTVLPLVRGSGFLVPFQKLNGFYKYHVLSAAHVTCPVRYRQVYGNTVGLRAIGERHVSTRLLKLGAGPALEASIDMEFTQNYLPNVDVSSLRCKDEKQMNELGLEAVKLDMDPIEDGTELIFRGVEASEERSNPNDDGLRLSEVSIPGECKAAFVSTDYGTVVLASLKSALSLSMCGGPVIRKSSGGCVGVIVAKAMCSAPPRDPHVRSLYEDPWLDLSEHKDLRGLGELSAAFVPVCEFYGPLRRCEM
Protein: Kelch repeat-containing protein 3 (Q08979)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Biogenesis of lysosome-related organelles complex 1 subunit KXD1
- Pre-rRNA-processing protein PNO1
Sequence:
MAKKNKKDKEAKKARAELKNQKNQKKQEKKFQKNKNKSLNGEEDDESDQDLDEILSSFSKKQIELEHVDITSVEKPSCRTHPLMFANPQHNKHELFIFGGEFTDPETKLTHFYNDLYSYSIKNNSWKKYVSQNAPLPRSSAAVAVHPSGIALLHGGEFSSPKQSKFYHYSDTWLFDCVERKFTKLEFGGRDSSPSARSGHRIIAWKNYFILFGGFRDLGNGQTSYLNDLWCFDISTYKWTKLETNSKPDARSGHCFIPTDNSAILMGGYCKIIAKNNKNLMKGKILNDAWKLNLTPDPKKWQWEKLKNFKNQPSPRVGYSFNLWKQNKSVAFGGVYDLQETEESLESVFYNDLYMFHLELNKWSKLRIKPQRQTNSKNSPATSKRKSNKDQEKELQDLLNSILAKSNLNDDDDDNDDNSTTGPNSIDDDEDNEDDSDLDNQEDITISNQLPHPRFNAATCVVGDSLFIYSGVWELGEKDYPINSFYSIDLNKLDGVKVYWEDLSAIEEAKRLGDRDSDEDEFEYEDDEEDEDDGEEEQDAGPLEGDEDEESESDDDKQAQMEIPDERSWLPHPKPFETLRAFYLREGANFLTWSISNNRNLKGKQLKTKSFELCEDRWWERRDQVTLEEERLEDTGGIIERDTTTKPSKRR
Protein: PROP1-like PPR domain-containing protein (Q54JI6)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MLNLNKSFKIINYSFLIKNVIRNYGSNKSIPTIITKPKENIKNINEIKETKIKIKNNNNNNDHSTENSLVVKKFNNSHIMERDPQDRSLSLKQYFEKLADRGDVDRMLQVARRMPERRTAYAYDKLIFACSKAHKFNQSWKIYNDMKKDNIKPSIHVFGNLVDICNHSTSIDSNKIQERVNKIIEEIDKYQVPVSINFFNILMKTMITIGNNDQAITMIDKMKDSGIRPDITSYTTWIKAISEKYLADNYLNKKELIKELNKPNKNTSEMDELRAEGNKQIDFYMTLVKKVKMAQISPDRYFINTILNACKQTKNPSGVFQVWDTLKEMRFTQHLNPDTKTYDILISTCNNIDDFDKSLEIFEEIFSKNIRPDIHLVNNMFRTCLRIASCRKISKKENLDEEIIINRIIDYMSAYSLQPNEESFSVLISTYSKLKNYVKVYELLLEMKELNISPNIKHYSGIISSFSKDTEKCLEILRICVSQKIVLTPDFISNVQKSISRHKGDVEQFSKLLREHDSYAIEKKIKNK
Protein: T-box transcription factor TBX4 (T-box protein 4) (P57082)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Pituitary homeobox 1
- Homeobox protein Hox-C10
- Homeobox protein Hox-C11
- Fibroblast growth factor 10
- PDZ and LIM domain protein 7
Sequence:
MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYHCLKRRDGTRHLDLPCKRSYLEAPSSVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQSQVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRESSLQYHSGMGTVENWTDG
Protein: Six3 (Homeobox protein Six6) (SIX homeobox 3b) (Sine oculis homeobox homolog 3b) (O73709)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Paired box protein Pax-6
- Visual system homeobox 2
- Homeobox protein OTX2
- LIM/homeobox protein Lhx9
- Sonic hedgehog protein
- Homeobox protein TGIF1
- Transcription factor atoh7
- ZIC family member 2, A
- ZIC family member 2 B
- Transcription factor Sox-2
Sequence:
MVFRSPLELYPSHLFLPNFADRPLLLAGSIPRARSPEDLPMFQLPTLNFSAEQVASVCETLEETGDIERLGRFLWSLPVAPGACDAINKHESIQRARAVVAYHTGSFRELYHILETHKFTKDSHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRGLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHHGLGQSSLRSMSESGCTPHSSAESPCAAASPTTSVSSMNERGDGGTILSVTDSDSDFDV
Protein: Rac family small GTPase 3 (A0A0G2JUG6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Ankyrin repeat and SAM domain-containing protein 3
- Glutamate-rich 5
- Centrosomal protein 250
- Centlein
- Actin, cytoplasmic 2
- Myosin IF
- small monomeric GTPase
- WD repeat-containing protein 37
- Unconventional myosin-VI
- Cytospin-A
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF
Protein: Iron uptake system component EfeO (P0AB24)
Organism: Escherichia coli (strain K12)
Function: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.
Subcellular location: Periplasm {ECO:0000269|PubMed:16551627}.
Interaction partners:
- Deferrochelatase
- Uncharacterized protein YncE
- Dye-decolorizing peroxidase YfeX
- Catecholate siderophore receptor Fiu
Sequence:
MTINFRRNALQLSVAALFSSAFMANAADVPQVKVTVTDKQCEPMTITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMTCGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDAIKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHRLEKALFGDNTTKGMDQYAEQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKISGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKYRTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD
Protein: LP07209p (Q9V9V8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- LD26135p
Sequence:
MPNRNCRTCGLFIFCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRERVIRTQKTLQESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLPEEHLLEETEEPYEICEQNEQPQVKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLTEDEVVALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQAALDNPVELDVKASNGMQTGAKDEALLGKSGS
Protein: Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (P12281)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
Interaction partners:
- Molybdopterin adenylyltransferase
- Molybdenum cofactor guanylyltransferase
- Cyclic pyranopterin monophosphate synthase
- Molybdopterin-guanine dinucleotide biosynthesis adapter protein
- Molybdenum cofactor biosynthesis protein B
- Molybdopterin-synthase adenylyltransferase
- Molybdopterin synthase catalytic subunit
- GTP 3',8-cyclase
- Molybdopterin synthase sulfur carrier subunit
- Formate dehydrogenase H
Sequence:
MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPFNALFGGL