wanglab/gogpt-training-data huggingface dataset:
Protein: E3 ubiquitin-protein ligase Trim36 (EC 2.3.2.27) (Acrosome RBCC protein) (Haprin) (RING-type E3 ubiquitin transferase TRIM36) (Tripartite motif-containing protein 36) (Q80WG7)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9NQ86}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:12917430}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19232519}. Note=Found in the acrosomal region of elongated spermatids and mature sperm (PubMed:12917430). Colocalizes with alpha-tubulin (PubMed:19232519). {ECO:0000269|PubMed:12917430, ECO:0000269|PubMed:19232519}.
Interaction partners:
- Centromere protein H
Sequence:
MSESEEISEFGYIMELLAKGKVTIKNIEKELICPACKELFTHPLILPCQHSVCHKCVKELLLSLDDSFNDVASDSSNQSSPRLRLTSPSMDKIDKINRPGWKRNSLTPRPTTFPCPGCEHDVDLGERGVSGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIYHPWGTVKAQHEYVGPTTNFRPKVLMCPEHETERINMYCELCRRPVCHLCKLGGNHSNHRVTTMSSAYKTLKEKLSKDIDFLIGKESQVKSQISELNLLMKETECNGERAKEEALAHFEKLFEILEDRKSSVLKAIDASKKLRLDKFHTQMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQASFEDYVVNISKQTEVLGELSFFSSGIDIPEINEEQSKVYNNALIDWHHPEKDKADSYVLEYRKINRDEEMISWNEIEVHGTSKVVSNLESNSPYAFRVRAYRGSICSPCSRELILHTPPAPVFSFLFDEKCGYNTEHLLLNLKRDRVESRAGFNVLLAAERIQVGHYTSLDYIIGDVGVTKGKHFWACRVEPYSYLVKVGVASSDKLQEWLRSPRDAASPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMKKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVSFYDMDHMKCLYERQVDCSHTMYPAFALMGSGGIQLEEAITAKYLEYEEDV
Protein: Small ribosomal subunit protein eS25 (40S ribosomal protein S25) (P48588)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- 40S ribosomal protein S27
- 60S ribosomal protein L27
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein eL21
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL11
- Small ribosomal subunit protein eS10A
- FI01658p
Sequence:
MPPKKDAKSSAKQPQKTQKKKEGSGGGKAKKKKWSKGKVRDKLNNQVLFDKATYEKLYKEVPAYKLITPSVVSERLKIRGSLAKRALIELREKGLIKQVVQHHSQVIYTRATKGDEA
Protein: Subtilisin-like protease SBT6.1 (EC 3.4.21.-) (Site-1 protease) (AtS1P) (Subtilase subfamily 6 member 1) (AtSBT6.1) (Q0WUG6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL motif. Targets the membrane-associated BZIP17 factor, which functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes. Cleaves the pectinesterases PME1 after the Arg-Arg-Leu-Met (RRLM) and Arg-Arg-Leu-Leu (RRLL) motifs, and PME5 after the Arg-Arg-Leu-Leu (RRLL) and Arg-Lys-Leu-Met (RKLM) motifs. This processing and C-terminus release occurs in the Golgi apparatus and is required for cell wall targeting of pectinesterases. Thus, SBT6.1 mediates the regulated release of mature pectinesterases from the Golgi. Cleaves the peptide growth factor RALF23 after the Arg-Arg-Ile-Leu (RRIL) motif. This processing is required for RALF23 function in the negative regulation of brassinolide (BL)-mediated signaling pathway (e.g. BL-induced hypocotyl elongation and branching limitation).
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:17662035, ECO:0000305|PubMed:20876872}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Membrane-bound transcription factor site-2 protease homolog
- bZIP transcription factor 17
- bZIP transcription factor 28
- bZIP transcription factor 60
- Rapid alkalinization factor 23
- Serine/threonine-protein kinase/endoribonuclease IRE1b
- Heat shock 70 kDa protein BIP3
- Sphingosine kinase 2
- Serine/threonine-protein kinase/endoribonuclease IRE1a
- Basic leucine zipper 8
Sequence:
MKVLGEASSYPYRSCIIVVFLSVSLFWLRPSTYHPQQQNLNPENVTRLESENETKTNYIIRFKQYKPAKDHRIYLESKVRSGGWGWIERINPATKYPTDFGVLWIEESGKEAVVGEIERLEMVKDVNVEFKYQRVLLGGSFPDGKKRPGKIFTSMSFEEGTESSPMADTSNTTLNWSRHLLAQKTQVTSMFGADHLWKKGYTGAKVKMAIFDTGIRADHPHFRKIKERTNWTNEDTLNDNLGHGTFVAGVIAGRNPECLGFASDTEIYAFRVFTDAQVSYTSWFLDAFNYAIATDMDVLNLSIGGPDYLDLPFVEKVWEITASNIIMVSAIGNDGPLYGTLNNPADQSDVIGVGGIDNDDHIASFSSRGMSTWELPHGYGRVKPDVVAYGRDIMGSKISTGCKSLSGTSVASPVVAGIVCLLVSVIPEARRKDLLNPASMKQALVEGAAKLSGPNMYEQGAGRVDLLESYEILKSYHPRASIFPSILDYNDCPYSWPFCRQPLYAGAMPIIFNTTILNGMGVIGYIESPPTWHPANEEGNLLSIHFKYPDVIWPWTGYLALHMQIKEEGAQFTGEIEGNVTVKVYSPPASGESGPRRSTCSLQLKLKVIPTPPRAKRILWDQFHSIKYPPGYIPRDSLDVRNDILDWHGDHLHTNFHIMYNMLRDAGYYIETLGSPLTCFDAQQYGTLLMVDLEDDYFPEEIEKLRDDVINTGLGLVVFAEWYNVDTMVKMRFFDDNTRSWWTPVTGGANIPALNNLLASFGIAFGDKILNGDFSIDGEQSRYASGTNIVRFPAGGFLHTFPLLDSSESGATQNLLLTEASKEDPAVLGLLEIGEGRVGVYGDSNCLDSSHMVTNCYWLLKKMLDFSSSNIKDPVLFSKFAKRYSPVIIDEKQLPSRRTDVNFSTYSSVIGKELICESDSRFEVWGTKGYNLHVRGRNRRLPGYHGIDLGRGLNFTVESKRPTRWRSAKEGGELSSSRSKSLGGLFNRDEIDMPFLVPTRWIVLAGVVASGVLVLLSIWRIRQKRGRRRRASGSNRLA
Protein: Short-chain dehydrogenase/reductase family 9C member 7 (SDR9C7) (EC 1.1.1.-) (O-acylceramide dehydrogenase) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S) (Q8NEX9)
Organism: Homo sapiens (Human)
Function: Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19703561}. Note=Granular distribution in the whole cell.
Interaction partners:
- Omega-hydroxyceramide transacylase
- Arachidonate 12-lipoxygenase, 12R-type
- Ultra-long-chain fatty acid omega-hydroxylase
- Retinaldehyde-binding protein 1
- Lecithin retinol acyltransferase
Sequence:
MAALTDLSFMYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEPRVRDVINSMEHAIVSRSPRIRYNPGLDAKLLYIPLAKLPTPVTDFILSRYLPRPADSV
Protein: Calcitonin (P01257)
Organism: Rattus norvegicus (Rat)
Function: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Subcellular location: Secreted.
Interaction partners:
- Calcitonin gene-related peptide type 1 receptor
- Calcitonin receptor
- Receptor activity-modifying protein 1
- Receptor activity-modifying protein 2
- VIP peptides
- Guanine nucleotide-binding protein G
- Calcitonin gene-related peptide 2
- Guanine nucleotide-binding protein subunit gamma
Sequence:
MGFLKFSPFLVVSILLLYQACGLQAVPLRSTLESSPGMATLSEEEARLLAALVQNYMQMKVRELEQEEEQEAEGSSLDSPRSKRCGNLSTCMLGTYTQDLNKFHTFPQTSIGVGAPGKKRDMAKDLETNHHPYFGN
Protein: Calumenin (CBP-50) (Crocalbin) (O35783)
Organism: Rattus norvegicus (Rat)
Function: Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O43852}. Golgi apparatus {ECO:0000250|UniProtKB:O43852}. Secreted {ECO:0000250|UniProtKB:O43852}. Melanosome {ECO:0000250|UniProtKB:O43852}. Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:O43852}.
Interaction partners:
- Calreticulin
- Calreticulin
- Calreticulin
- Endoplasmic reticulum chaperone BiP
Sequence:
MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFGQLTPEESKEKLGMIVDKIDTDKDGFVTEGELKSRIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKPIMVRDERRFKMADQDGDLIATKEEFTAFLHPEEYDYMKDIVLQETMEDIDQNADGFIDLEEYIGDMYSHDGNADEPQWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQDKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
Protein: diphosphoinositol-polyphosphate diphosphatase (EC 3.6.1.52) (F4I780)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKLVEKTTTTEQDNGEDFCRTIIEVSEVNRNVFQAPGGEADPFRVVSGEELHLIPPLNFSMVDNGIFRSGFPDSANFSFLQTLGLRSIIYLCPEPYPESNLQFLKSNGIRLFQFGIEGNKCVPDLDNEISLHLWNSKHQKQGPLTNGLSKTLEPFVNIPDHKIRMALKVLLDEKNHPVLIHCKRGKHRTGCLVGCLRKLQKWCLTSIFDEYQRFAAAKARVSDQRFMEIFDVSSFSHIPMSFSCSIR
Protein: Protein MGA1 (P53050)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MQPKTFVHQLHAILLEPEVNKWIYWSPTDNTVFFLKPYDPNFSTHVLKRYFKHGNVNSFVRQLHMYGFHKLSHPSPDQSSANNGNVKELVEWKFTHPSGFFFKEANAGILNKIQRKSTGVGKDGKRKNILSPISVSYVDASRLNVLSQQSGPVSAREPSNMFMGSPVHYSTSQSPPHISIPQQQQSSGPYLISSLPPQQPTVNMMRRQSISARMMNSYDYPNQFSTQDSIVQPQQPQQVLSPQALSGPPMKKSGTLSSTDDLKTTSLPIVNYPMPYHPGAFAQQQQQQQQPLPTVPPYSSYSTPFPSMMNSLSNSASNSPALGVCNNNVTLPKKSNISERQALDNHIQTLKNSLSTITDLIEKHINSASQDENKTLTNDAMNKDLRTSLSLLQNSKEEIIQLESKWMSMQSVKTTALPLQETTNTSSTLTSLTSSIIPKSIPIITKGEVATKPASY
Protein: UDP-glycosyltransferase 73B3 (EC 2.4.1.-) (Flavonol 3-O-glucosyltransferase UGT73B3) (EC 2.4.1.91) (Q8W491)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses quercetin 3-O-glucosyltransferase activity in vitro. Also active in vitro on benzoates and benzoate derivatives. Involved in stress or defense responses.
Interaction partners:
- Probable L-type lectin-domain containing receptor kinase VII.2
Sequence:
MSSDPHRKLHVVFFPFMAYGHMIPTLDMAKLFSSRGAKSTILTTPLNSKIFQKPIERFKNLNPSFEIDIQIFDFPCVDLGLPEGCENVDFFTSNNNDDRQYLTLKFFKSTRFFKDQLEKLLETTRPDCLIADMFFPWATEAAEKFNVPRLVFHGTGYFSLCSEYCIRVHNPQNIVASRYEPFVIPDLPGNIVITQEQIADRDEESEMGKFMIEVKESDVKSSGVIVNSFYELEPDYADFYKSVVLKRAWHIGPLSVYNRGFEEKAERGKKASINEVECLKWLDSKKPDSVIYISFGSVACFKNEQLFEIAAGLETSGANFIWVVRKNIGIEKEEWLPEGFEERVKGKGMIIRGWAPQVLILDHQATCGFVTHCGWNSLLEGVAAGLPMVTWPVAAEQFYNEKLVTQVLRTGVSVGAKKNVRTTGDFISREKVVKAVREVLVGEEADERRERAKKLAEMAKAAVEGGSSFNDLNSFIEEFTS
Protein: N-acetylaspartate synthetase (NAA synthetase) (N-acetyltransferase 8-like protein) (EC 2.3.1.17) (D3ZVU9)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA. Promotes dopamine uptake by regulating TNF-alpha expression (By similarity). Attenuates methamphetamine-induced inhibition of dopamine uptake (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8N9F0}. Microsome membrane {ECO:0000269|PubMed:18621030}; Single-pass type I membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:18621030}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q3UGX3}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Aspartoacylase
- Ribosomal modification protein rimK-like family member B.
- Glutamate carboxypeptidase 2
- Asparagine synthetase
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase, mitochondrial
- Amine oxidase
- Argininosuccinate synthase
- Multifunctional protein CAD
- Amine oxidase
Sequence:
MHCGPPDMVCETKIVATEDHEALPGAKKDALLAAAGAMWPPLPAAPGPAAAPPPAAGPQPHGGTGGAGPPEGRGVCIREFRAAEQEAARRIFYDGILERIPNTAFRGLRQHPRTQLLYALLAALCFAVTRSLLLTCLVPAGLLALRYYYSRKVILAYLECALHTDMADIEQYYMKPPGSCFWVAVLDGNVVGIVAARAHEEDNTVELLRMSVDSRFRGKGIAKALGRRVLEFAMLHNYSAVVLGTTAVKVAAHKLYESLGFRHMGASDHYVLPGMTLSLAERLFFQVRYHRYRLQLREE
Protein: Heat shock transcription factor 4 (A0A096MK39)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Phakinin
- Filensin
- Gamma-crystallin D
- Gamma-crystallin S
Sequence:
MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGCEQLLERVRRKVPALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGAKRKLSLMLDEGSACSASAKFNACPVSGALLQDPYFIQSPLPETTVGLSPHRARGPIISDIPEDCPSPEGHRLSPSSAGRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRSIQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPVLLRPPPETVEPMDALGPSLHGREWTLMDLDMELSLMQPLAPERAEAELTVKDLTSSGVGKDHTLGTPLMLDVQADLEGAALSVPGALTLYNATESNASYLDPGASPSSP
Protein: Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase) (P13929)
Organism: Homo sapiens (Human)
Function: Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. Appears to have a function in striated muscle development and regeneration.
Subcellular location: Cytoplasm. Note=Localized to the Z line. Some colocalization with CKM at M-band (By similarity). {ECO:0000250}.
Interaction partners:
- Pyruvate kinase PKM
- Phosphoglycerate mutase 2
- Phosphoglycerate mutase 1
- Probable phosphoglycerate mutase 4
- Pyruvate kinase PKLR
- Glucose-6-phosphate isomerase
- Bisphosphoglycerate mutase
- Fructose-bisphosphate aldolase A
- Triosephosphate isomerase
- Phosphoenolpyruvate carboxykinase, mitochondrial
Sequence:
MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAIFAGRKFRNPKAK
Protein: Protein EGT2 (Early G1 transcript 2) (P42835)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Seems to be involved in the correct timing of cell separation after cytokinesis, as separation of mutant daughter cells is delayed. Could either be an enzyme necessary for glucans-degradation of the cell wall at the neck region between mother and daughter cells or a regulatory protein controlling this metabolic step.
Subcellular location: Secreted, cell wall {ECO:0000305|PubMed:15452134, ECO:0000305|PubMed:9613572}. Membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. Note=Localizes to the septum of dividing cells.
Interaction partners:
- Glucan endo-1,3-beta-D-glucosidase 1
- Protein DSE2
- Probable secreted beta-glucosidase SUN4
- Endochitinase
- Probable family 17 glucosidase SCW11
- Protein DSE1
- Protein DSE3
- Antagonist of mitotic exit network protein 1
- Transcriptional factor SWI5
- Transcriptional regulatory protein ASH1
Sequence:
MNKLLLHLVRVISILGLANALTQTQPILKDIQITDSYTKTKECTDPDHWFIIEGQLSIPKGSQQNITFQVPDAFSSFPQEPFSIKHNSNSVATISRPDKSTNNFTISIPEKSSEDITTTFNFLAQLTSDAKSKVTEPKSIVYSFYSENTMFNDVIDYVAKNTSAITTDGGIYKTNNTAWFTVDLPMRTFRNPVYLTSQTSSSSDYVFDTSLTKFEVVTAVDSFNEPINAIPYTTVHDYSTEDEIRCLFNSTISGGLYFRVTYFTKKLSTSSISNTVELTYPDEGTSVRLLGKRDTSTTLASELYSESAANIDSTTSDDTTSSDAAITPTYSNSTLSSYTSQSSAIPEVAVTASLSSGILSSTVDGASTSADASMSAVSTVSSSSEQASSSSISLSAPSSSNSTFTTPSSSLSATETYSIISSASISVTQASYIDNSTTTAVTQSTSTIAVSSAEKLSSTLSYTSNVTISVSSATQHTTTPSYVSNSTTLSSSSVLESVISSPYLANTTVSGASSASQSTNPPYVSNSTTSSATQLATIAPFAINITGTSISSSITNTSSVSSTTSSLSSGPFVSNTTVASGSYILTTTTESAQLTEIGSLIPISTITTSTTTSGTDKTGSNKVASSTEIAQSIVNNSSLSVSTINTNAATAAANARNATFTHATHSGSLQPSYHSSSLLSSTIDTKVTTATTSTSRDGSSSLAFTTGLNQSVVTGTDKSDTYSVISSTESAQVTEYDSLLPISTLKPTVVTGTSRNSTFSMVSSTKLTEATATDKGDAYSVISSTQSAQVTEYGSMLPISTLETPTVIMSTDESGYFTLTTCTESGQATEYGSLIPISTLDGSVIYTFTGESVVVGYSTTVGAAQYAQHTSLVPVSTIKGSKTSLSTEESVVAGYSTTVGAAQYAQHTSLVPVSTIKGSKTSLSTEESVVAGYSTTVDSAQYAEHTNLVAIDTLKTSTFQKATATEVCVTCTALSSPHSATLDAGTTISLPTSSSTSLSTIITWYSSSTIKPPSISTYSGAAGQLTIRIGSLLLGLISFLL
Protein: BBSome complex member BBS5 PH domain-containing protein (A8HWI3)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Subcellular location: Cell projection, cilium membrane {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000256|ARBA:ARBA00004607}.
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Bardet-Biedl syndrome 9
- Uncharacterized protein
- Bardet-biedl syndrome 7 protein
- Bardet-Biedl syndrome 2 protein homolog
- Uncharacterized protein
- Uncharacterized protein
- Intraflagellar transport protein 57
- ADP-ribosylation factor-like protein 6
Sequence:
MADLFGARPEPNLCWQDREIRFDCNANDINLRQGEELITLMDSVEDTKGNNGDLGELRVSNLRLCWVNKKNRRTNICIGHNCITTVNVRAATSRIKGSTQSLYVLTKYHNQRFEFIFTATASESATDSLFASMQGVFRAYDSSRLYRDLKLRGALIMDRELRLLPLEQTYSRVNGVWNLSAEQGNLGTFFISNVRVVWYANLAENFNVSIPYLQIRSVKVRESKFGQALVIETSPASGGYVLGFKVDPKETLDYVFKEISSLWQVYAANPVFGVEYRPDASGLAGAASGILPSEQDVEIVEPADRGDALAQYYADGAGGKGADRDPTYCAELGLAVEGLKEGLTVEQLWSVL
Protein: ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] (EC 2.5.1.87) (Q9VPX8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}.
Interaction partners:
- Alkyl transferase
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Protein farnesyltransferase subunit beta
- Decaprenyl diphosphate synthase subunit 2, isoform A
- All trans-polyprenyl-diphosphate synthase PDSS1
- Farnesyl pyrophosphate synthase
- Quemao, isoform A
- Ribosome-recycling factor, mitochondrial
- LP09696p
- Bifunctional glutamate/proline--tRNA ligase
Sequence:
MIEVLCLLLGRILLLLVGGYELMWRLRERLNALAVRSYDLWRSKAAREAHERRVLADCRSQLTKTPQHLVLVISPVDAGVDAVLLSRIFDFALDVGIKHVSLYDRRTKGRGYVDMADLCRSTNADTGSCLKWPPVASPSKLENQPKNGQKTNGYVNGSHSPQLQLHQISASDGHALIADVCRELYEDSKTELVQSLLKQKREALTEQISDMLSKRLGFEAPEPELGIVFARQTCTYGLLPWHARFTEFHTHPSGRHFDVETFASILCKYSRCEQRWGT
Protein: Transporter (Q4FIV7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MAEKQFSNILNGAVPGEPVKRDENSRRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLVFCGIPLFFLELSFGQFTSLGCLGVWKVSPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFMSMTNLLPWTYCNNPWNTPDCSGVVSTHRANATFANMSAVVSGVTEIVNRTKRTSPSEEYWRNYVLNISDGIGNFGEVRLPILGCLAVSWFVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFIRGITLDGAISGIKYYLTPQWQKILDAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCFRDSIIISVTNCGTSVYAGFVIFSILGFMAHHLGVDVSEVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAVVDEIGTDWIIKNKTYVTLGVAIIGFLLGVPLTTQAGIYWLLLMDNYAASFSLVIISCIMCICIMYVYGHKNYFKDVEMMLGFPPPIFFRICWRYVSPFIITFILIFTVIQYKPITYNDYVYPGWSLVIGFAMALSSVICIPIYALFKIAMSEGSTFLERLKNSVKPDPDWGPALQEHRKGRYATAGPESVEVSPLKEDLKDEGKDKLTEKEKETEKKDEIGLTIPGSNGSTLNPTPSA
Protein: Nitrogen regulatory protein P-II (P13556)
Organism: Rhodobacter capsulatus (Rhodopseudomonas capsulata)
Function: P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme.
Interaction partners:
Sequence:
MKKVEAIIKPFKLDEVKEALQEAGIQGLSVIEVKGFGRQKGHTELYRGAEYVVDFLPKVKIEMVLPDEMVDIAIEAIVGAARTEKIGDGKIFVSSIEQAIRIRTGETGEDAV
Protein: Regulatory protein NPR6 (BTB/POZ domain-containing protein NPR6) (Protein BLADE-ON-PETIOLE 1) (Q9M1I7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB, YAB1/FIL and YAB3, and through positive regulation of LOB domain-containing genes LOB, LBD6/AS2 and LBD36. Promotes and maintains a developmentally determinate state in leaf cells through the negative regulation of JAG, JGL and class I KNOX genes. Is also involved in nectary development, formation of normal abscission zones and suppression of bract formation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20118228}. Nucleus {ECO:0000269|PubMed:20118228}.
Interaction partners:
- Transcription factor TGA6
- Transcription factor TGA2
- Transcription factor TGA5
- Transcription factor TGA7
- Ankyrin repeat-containing protein BDA1
- AT3G13950 protein
- Ankyrin
- RNA polymerase II transcriptional coactivator KIWI
- SNARE associated Golgi protein family
Sequence:
MSNTFEESLKSMSLDYLNLLINGQAFSDVTFSVEGRLVHAHRCILAARSLFFRKFFCESDPSQPGAEPANQTGSGARAAAVGGVIPVNSVGYEVFLLLLQFLYSGQVSIVPHKHEPRSNCGDRGCWHTHCTAAVDLSLDILAAARYFGVEQLALLTQKHLTSMVEKASIEDVMKVLIASRKQDMHQLWTTCSYLIAKSGLPQEILAKHLPIELVAKIEELRLKSSMPLRSLMPHHHDLTSTLDLEDQKIRRMRRALDSSDVELVKLMVMGEGLNLDESLALIYAVENCSREVVKALLELGAADVNYPAGPTGKTALHIAAEMVSPDMVAVLLDHHADPNVQTVDGITPLDILRTLTSDFLFKGAIPGLTHIEPNKLRLCLELVQSAALVISREEGNNNSNDNNTMIYPRMKDEHTSGSSLDSRLVYLNLGATNRDIGDDNSNQREGMNLHHHHHDPSTMYHHHHHHF
Protein: Protein PERCC1 (Proline and glutamage-rich protein with a coiled coil domain) (A0A286YDK6)
Organism: Mus musculus (Mouse)
Function: Plays a critical role in intestinal function by promoting the development of enteroendocrine cells (EECs) of the gastrointestinal tract and pancreas. It is thereby required for normal enteroendocrine peptide hormone secretion.
Interaction partners:
Sequence:
MAAGVIRSVCDFRLPLPSHESFLPIDLEAPEISEEEEEEEEEEEEEEEEEEVDQDQQGEGSQGCGPDSQSSGVVPQDPSSPETPMQLLRFSELISGDIQRYFGRKDTGQDPDAQDIYADSQPASCSARDLYYADLVCLAQDGPPEDEEAAEFRMHLPGGPEGQVHRLGHRGDRVPPLGPLAELFDYGLRQFSRPRISACRRLRLERKYSHITPMTQRKLPPSFWKEPVPNPLGLLHVGTPDFSDLLASWSAEGGSELQSGGTQGLEGTQLAEV
Protein: 29 kDa ribonucleoprotein, chloroplastic (RNA-binding protein CP29A) (RNA-binding protein cp29) (Q43349)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Stabilizes specific chloroplast mRNAs. Required for normal chloroplast development under cold stress conditions by stabilizing transcripts of numerous mRNAs under these conditions.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein CP26, chloroplastic
- Photosystem II CP43 reaction center protein
- Photosystem II 22 kDa protein, chloroplastic
- Chlorophyll a-b binding protein 3, chloroplastic
- Serine/threonine-protein kinase STN7, chloroplastic
- Chlorophyll a-b binding protein 6, chloroplastic
- Chlorophyll a-b binding protein CP29.1, chloroplastic
- Oxygen-evolving enhancer protein 1-1, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 2, chloroplastic
Sequence:
MSASASSLSAFNPKSLPLCVSRPASVSVLPPSLSFKLHSDHLVSIFASSALKCSSPAEYPSRFVRNVAVSSDFEVEEDDMFADGDDSAPVERNSFSPDLKLFVGNLSFNVDSAQLAQLFESAGNVEMVEVIYDKVTGRSRGFGFVTMSTAAEVEAAAQQFNGYEFEGRPLRVNAGPPPPKREESFSRGPRSGGYGSERGGGYGSERGGGYGSERGGGYGSERGGGYGSQRSGGGYGGSQRSSYGSGSGSGSGSGSGNRLYVGNLSWGVDDMALENLFNEQGKVVEARVIYDRDSGRSKGFGFVTLSSSQEVQKAINSLNGADLDGRQIRVSEAEARPPRGQF
Protein: RE29317p (Q5BID5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEYGNTKVLAIVAPPKELIRASARRMNMGVLNCYVNFAAFSTGDLDSVPERERHLSSMLTKAMEPVVCRTEFLNFQLDIRVLILDDDGCLLSTAINCCGVALVECGISTYDLITASTACIYRDHVFLNPSAKVEELLWKHRNSSTDSTTSPSSAQEHGLIITASMDTFEQIAQCQQCGYLSPATYVKLLDYTLAINKSLRELVKGVLTKRVKEQHELDLREKAETALEDQRLEEIIEKLKKQGPEEFIQSNIREDPYVKRQ