wanglab/gogpt-training-data huggingface dataset:
Protein: D-2-hydroxyglutarate dehydrogenase, mitochondrial (AtD-2HGDH) (EC 1.1.99.39) (O23240)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the oxidation of (R)-2-hydroxyglutarate to 2-oxoglutarate. May be involved in the catabolism of propionyl-CoA derived from beta-oxidation. Involved in degradation of lysine for the supply of carbon and electrons to the ETF/ETFQO complex during dark-induced sugar starvation.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:19586914, ECO:0000269|PubMed:21296880, ECO:0000305|PubMed:25732537}.
Interaction partners:
- Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
- Electron transfer flavoprotein subunit beta, mitochondrial
- Isovaleryl-CoA dehydrogenase, mitochondrial
- Electron transfer flavoprotein subunit alpha, mitochondrial
Sequence:
MMMQKLRRSGEFIRFGCKSLISSRPNKDSVSRSVSGFVNHYKSKGKLFELSDGNYKTELHHPCISRNVGMLLQQYKCFGSSAASLIQRNPLFSSLDSKDVSYFKEILGEKNVVEDKERLETANTDWMHKYKGSSKLMLLPKNTQEVSQILEYCDSRRLAVVPQGGNTGLVGGSVPVFDEVIVNVGLMNKILSFDEVSGVLVCEAGCILENLATFLDTKGFIMPLDLGAKGSCHIGGNVSTNAGGLRLIRYGSLHGTVLGLEAVTANGNVLDMLGTLRKDNTGYDLKHLFIGSEGSLGIVTKVSILTQPKLSSVNLAFIACKDYLSCQKLLVEAKRNLGEILSAFEFLDNNSMDLVLNHLDGVRNPVSSSENFYILIETTGSDETNDREKLEAFLLKSLEKGLVSDGVIAQDINQASSFWRIREGITEALQKAGAVYKYDLSLPVEEIYNIVNDLRGRLGDLANVMGYGHLGDGNLHLNISAAEYNDKLLGLIEPYVYEWTSKHRGSISAEHGLGVMKANEIFYSKSPETVALMASIKKLLDPKGILNPYKVLPHSLFSN
Protein: Mll1/2 (L0H974)
Organism: Schmidtea mediterranea (Freshwater planarian flatworm)
Interaction partners:
Sequence:
QQDPPVMLRLNKIQPQRLPPSIVKQLNINQNQSKPLTFIHLGQPINRISVKNPPMNNKIFKVMKVATSSSLSPATVGVGNSSTSIPISPLTTATKHPSLRIVTSRPPLSSSVLRTVLTDNSHSRRVVVHQQTQPALTIGTSKSSAYHISSCGSIITPSLAQFDGEGDDSSAVTFDEFRSILAAHPAHNVGSDQENASVITMATTTAVAGVKTRKQRANHDYKFCLRFTIHGFKGSKSPKSGWGLIVKRITQMRKSQGLMEYPVRNGDGWAKFGLDHRHVIYLVEQMVSAFQCNNYEFKFHKTRVTKLRNQYLADVVSPRGCVRFNQWTKTKPDHIARDPLAFLHSKSNYPPKNHAPLNADQLDDNPDPDEDYLRTLADQFRNLRNGM
Protein: AP-3 complex subunit mu (AP-3 adaptor complex mu3 subunit) (Adaptor-related protein complex 3 subunit mu) (Clathrin-adaptor medium chain Apm3) (Mu3-adaptin) (Q9GPF1)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.
Subcellular location: Endosome membrane {ECO:0000250}.
Interaction partners:
- AP-3 complex subunit beta
- AP-3 complex subunit delta
- AP-3 complex subunit sigma
- AP-1 complex subunit gamma
- AP-2 complex subunit alpha-2
- Arpin
- AP-4 complex subunit epsilon
- BEACH domain-containing protein lvsB
- AP-2 complex subunit sigma
- Vesicle-associated membrane protein 7A
Sequence:
MLSSFFIIADQGDILIEKHWRGLMNRSICEYFWDQVLQSKQNGSSVPPIISTPKYYLINIQKQNVYLLGVCQSEVSPLLVVDFLQRIYDTFVEYFGSNITSATIKENFVHVYQLLDEMADNGFPFTTELNFLKEMIKPPGVLSNVISSVTGTSNITDILPNGSLGAIQWRKTGIKYTQNKIFFDIIEEIDCIIDSNGYIVSSEINGEILCHCNLSGMPDLTMTFNNPRMLDDVSFHPCVRYSRWENDRVLSFIPPDGNFKLLSYRVKGINQFPVYVKPQISYSEGSSSVGRVNVTVGAKGYNVQNKLSIEDVVATIPFSKTTSSTNLTANIGSFGMDEQSKILRWNIGKIPKEKTPFLNGTVSLIAGSMTPESTPSIMLQFKIPQYAISGLTIDSLACSERYKPFKGVKCTTKAGKFQVRS
Protein: Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Q8BIP0)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:Q6PI48}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q6PI48}.
Interaction partners:
- Glutamyl-tRNA
- Bifunctional glutamate/proline--tRNA ligase
- Aspartate--tRNA ligase, cytoplasmic
- Valine--tRNA ligase
- Alanine--tRNA ligase, mitochondrial
- Tyrosine--tRNA ligase, cytoplasmic
- Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial
- Valine--tRNA ligase, mitochondrial
- Probable arginine--tRNA ligase, mitochondrial
- Alanine--tRNA ligase, cytoplasmic
Sequence:
MYLGFWLSRLCRGLSRPIGKTMRPIWGSLSRNLALSSQRIPEFSSFVARTNTCGELRSSHLGQEVTLCGWIQYRRQNTFLVLRDCHGLVQILIPQDESAASVRRILCEAPVESVVRVSGTVISRPPGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKDFVKKTEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVEQTGIQRLVEGLLQYSWPGDKDPLVTPFPSMTFAEALATYGTDKPDTRFGMKIVDVSDVFRNTELRFLQDALAKPQGTVKAICVHDGAKYLRKEDIEFIRKFAVHHFSQEVLPIFLNAKKNWSSPFAKFIMEEERLELARSMEIQEEDIVLLTAGEHEKACSLLGKLRLECADLLEMRGAVLRDPAVFSFLWVVDFPLFLAKEESPTELESAHHPFTAPNSSDIHLLYTEPEKVRGQHYDLVLNGNEIGGGSVRIHDAQLQRYILETLLKEDVKLLSHLLQALDYGAPPHGGIALGLDRLVCLVTGAPSIRDVIAFPKSYRGQDLMSNAPDSVSPEELKPYHIHVLWPADSEEESASATPSKHLSS
Protein: Gst2p (Q5AFB4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- glutathione transferase
- Glutathione reductase
- Gst1p
- Gst3p
- Thioredoxin peroxidase
- Protein URE2
- Ecm38p
- Glutathione hydrolase
- Glutathione synthetase
- Gtt1p
Sequence:
MTKPIQFYTYGTPNGFKVSIFLEVLGLAYETISVDITKNESKSDWFVKLNPNGRIPTIVDPNFKDGEITISQTGAILQYLADNYDKEHKYSYAFGTEEYYKTLEYLIFQVSENGPIQGQLNHFKLFAKEKIEYGITRYENDTKRIYGVYEDILKRNSANDSKYLVGDRYTVADYALFGWAYSLHKVGIDIHDWPLLGKWFDALNKDPAVIKGVNVPEKK
Protein: Choline kinase (EC 2.7.1.32) (Q8IM71)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- choline-phosphate cytidylyltransferase
- Phosphoethanolamine N-methyltransferase
- ethanolamine kinase
- ethanolamine-phosphate cytidylyltransferase
Sequence:
MESKICDPIGLDKNKFRKVEEENEENSKIVENGQMTYNDDLEMFTTIQLNQEIDIRKNPFPLHMINQKNDIPLCAQEFSKLTDPLYIKKICLEKVHDWSRCNEDDVCVNQILSGLTNQLFEVSIKEDTAIEYRITRRHVLFRIYGKDVDALYNPLSEFEVYKTMSKYRIAPLLLNTFDGGRIEEWLYGDPLSIDDLKNKSILVGIANVLGKFHTLSRKRHLPEHWDKTPCVFKMMDRWRLAVSNYKNLDKVTLDINKYIQESHKFLKFIKIYTQIENIANDIVFCHNDLQENNIMNTNKCLRLIDFEYSGYNFLSADIANFFIETTIDYSYNAYPFFIINKKNYISYESRILFVTTYLSKYLDDSTAASDQDIIDQFLEAIEVQALGLHLIWAFWSIIRGYQTKSYNEFDFFLYAKERLKMYDEQKQYLMSKNIIKDYDD
Protein: Zinc finger protein MSN4 (Multicopy suppressor of SNF1 protein 4) (P33749)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Positive transcriptional factor that acts as a component of the stress responsive system. Recognizes and binds to the stress response element (STRE) which is involved in the response to various forms of stress (heat, oxidative, osmotic, etc.). Involved in the regulation of the CTT1, DDR2, HSP12 genes.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Zinc finger protein MSN2
- Serine/threonine-protein kinase RIM15
- Serine/threonine-protein kinase SCH9
- Ras-like protein 2
- Transcriptional activator/repressor GIS1
- Mitogen-activated protein kinase HOG1
- cAMP-dependent protein kinase type 2
- cAMP-dependent protein kinase type 3
- cAMP-dependent protein kinase type 1
- Pheromone receptor transcription factor
Sequence:
MLVFGPNSSFVRHANKKQEDSSIMNEPNGLMDPVLSTTNVSATSSNDNSANNSISSPEYTFGQFSMDSPHRTDATNTPILTATTNTTANNSLMNLKDTASLATNWKWKNSNNAQFVNDGEKQSSNANGKKNGGDKIYSSVATPQALNDELKNLEQLEKVFSPMNPINDSHFNENIELSPHQHATSPKTNLLEAEPSIYSNLFLDARLPNNANSTTGLNDNDYNLDDTNNDNTNSMQSILEDFVSSEEALKFMPDAGRDARRYSEVVTSSFPSMTDSRNSISHSIEFWNLNHKNSSNSKPTQQIIPEGTATTERRGSTISPTTTINNSNPNFKLLDHDVSQALSGYSMDFSKDSGITKPKSISSSLNRISHSSSTTRQQRASLPLIHDIESFANDSVMANPLSDSASFLSEENEDDAFGALNYNSLDATTMSAFDNNVDPFNILKSSPAQDQQFIKPSMMLSDNASAAAKLATSGVDNITPTPAFQRRSYDISMNSSFKILPTSQAHHAAQHHQQQPTKQATVSPNTRRRKSSSVTLSPTISHNNNNGKVPVQPRKRKSITTIDPNNYDKNKPFKCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTHKKHGDF
Protein: Microtubule-associated protein RP/EB family member 2 (Microtubule-associated protein, RP/EB family, member 2) (Zgc:171788 protein) (A7MC00)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MPGPTQALSPNGENNNDIIPDNNGTNIIPYRKNTVRGERAYSWGMAVNVYSTSITQETMSRHDITAWVNDLLCLNYTKVEQLSSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKIIPVEKLVKGRFQDNLDFIQWFKKFFDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHAASSPTAGATRSTSSTPKSSTSTSTSTSRPSSAKKLPVMSATPAKGEKELEAQVTQLNEQMNTLKLALEGVEKERDFYFGKLREVELLCQEQGQDNGPFVERLMEVLYSADDQEAGGEEHEAPAQEEDVPDDTPALSRIDFLPIA
Protein: Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) (O35435)
Organism: Mus musculus (Mouse)
Function: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q02127}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q02127}.
Interaction partners:
- Uridine 5'-monophosphate synthase
- Multifunctional protein CAD
- Cytochrome b5 reductase 4
- NADH-cytochrome b5 reductase 1
- NADH-cytochrome b5 reductase-like
- NADH-cytochrome b5 reductase 2
- NADH-cytochrome b5 reductase 3
- Oxidoreductase NAD-binding domain-containing protein 1
- Trifunctional purine biosynthetic protein adenosine-3
- GMP synthase
Sequence:
MAWRQLRKRALDAAIILGGGGLLFTSYLTATGDDHFYAEYLMPALQRLLDPESAHRLAVRVISLGLLPRATFQDSNMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSAVEHRLRARQQKQTQLTTDGLPLGINLGKNKTSVDAAADYVEGVRILGPLADYLVVNVSSPNTAGLRSLQGKTELRRLLSKVLQERDALKGPQKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIITNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGTIPIIGVGGVSSGQDALEKIQAGASLVQLYTALTFLGPPVVARVKRELEALLKERGFNTVTDAIGVDHRR
Protein: Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) (Q42891)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
Interaction partners:
- hydroxyacylglutathione hydrolase
- hydroxyacylglutathione hydrolase
- Lactoylglutathione lyase
- Lactoylglutathione lyase
- Threonine dehydratase
- Threonine dehydratase 1 biosynthetic, chloroplastic
- Threonine dehydratase 2 biosynthetic, chloroplastic
- tryptophan synthase
- Tryptophan synthase
- Tryptophan synthase
Sequence:
MASESKDSPSNNPGLHATPDEATKGYFLQQTMFRIKDPKVSLEFYSKVLGMSLLKRLDFPEMKFSLYFMGYEDTASAPSDPVERTAWTFSQKSTLELTHNWGTESDPNFTGYHNGNSEPRGFGHIGVTVDDVYKACERFESLGVEFVKKPLDGKMKGIAFIKDPDGYWIEIFDTKIIKDAAGSAS
Protein: Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I) (P02803)
Organism: Rattus norvegicus (Rat)
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Interaction partners:
- Metallothionein 2, pseudogene 1
- Metallothionein-2
- Proton-coupled zinc antiporter SLC30A1
- Metal regulatory transcription factor 1
Sequence:
MDPNCSCSTGGSCTCSSSCGCKNCKCTSCKKSCCSCCPVGCSKCAQGCVCKGASDKCTCCA
Protein: cDNA FLJ37051 fis, clone BRACE2013624 (Q8N9J2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAHRNQRQSHGHLSRPFLLEPARGACSRDTFLSASPRLPRPRQAASLAHRPEKSAPGADCPSGRRAAALDVRGPLWAGRGASALPSSSRVRSYPLGSRGTARGPVRSRADMNARQSGLAAANGARARTRLGSTFQ
Protein: RE43539p (Uncharacterized protein, isoform D) (Q8I0J1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGGSLELAGGRRTRSSTRGTPTRAAEAVTPPPSKKARTSPASATKASAGKGRGARKLDVGADEPEPELEKEKEKVQTSVKGKGAVKKDKKEVKKQEKATEKYAPEEAKEDVAEAKEEDASPAGVQDQPDGVENLPSVAEAKQNHVDEVKPISEEPGNSSEEVPKAEEPLKSSGETSENGAATETAAAPKEPASVMDVDEDETLVENTPSANKEKALDDEKEPEQKSEEHAAAVLESKEQNEPAKEPTPEPMEVDGSSKGSSDTAQVDTPAIENVSAAPETEAAAKTTESSNDVVEVATEGKETVLEVPAAEPKEAESTVESAEELTETSTVVVTEPKEAASSEEEPSKVVDSAEPKEAESNTDESATPVPIDVSTAPASNDVSKPLEIDTTLVKTADSPAKEPQEICEVKKAEINVNGEPKIVNSSAEVGENAAPKVCN
Protein: Sorting nexin 5 (Q5QPE5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAK
Protein: 60S acidic ribosomal protein P0 (Q6FTP0)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- L1c
- Large ribosomal subunit protein uL3
- L2
- Candida glabrata strain CBS138 chromosome H complete sequence
- 60S ribosomal protein L27
- 60S ribosomal protein L29
- Candida glabrata strain CBS138 chromosome F complete sequence
- 40S ribosomal protein S26
- S16a
- Large ribosomal subunit protein eL31
Sequence:
MGGIREKKAEYFAKLREYLEEYKSIFVVGVDNVSSQQMHQVRKALRGRGVVLMGKNTMVRRAIRGFISDLPDYEKLLPFIKGNVGFIFTNESLKDIKEVIVANKVAAPARSGAVAPEDIWVKAMNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVEAGNRVGPSEASLLNLLNISPFTYGLTVVQVYDQGQVFPSTILDITDEELVSHFVSAVTTVAAISLAAGYPTLPSVGHTLINNYKNLLAVAIASSYHYPEIEELIDRIENPENYASAAPAAAAASGDAAPAEEAAAEEEDESDDDMGFGLFD
Protein: Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin; Kisspeptin-10 (Metastin45-54)] (Q7TSB7)
Organism: Rattus norvegicus (Rat)
Function: Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.
Subcellular location: Secreted.
Interaction partners:
- KiSS-1 receptor
- Uridine monophosphate synthetase, isoform CRA_a.
- Dihydropyrimidine dehydrogenase [NADP
- Dihydroorotate dehydrogenase
- Neuromedin-K receptor
- Gonadotropin-releasing hormone receptor
- Tachykinin-3
- Progonadoliberin-1
- Trifunctional purine biosynthetic protein adenosine-3
- Pro-FMRFamide-related neuropeptide VF
Sequence:
MISLASWQLLLLLCVASFGEPLAKMAPVVNPEPTGQQSGPQELVNAWQKGPRYAESKPGAAGLRARRTSPCPPVENPTGHQRPPCATRSRLIPAPRGSVLVQREKDMSAYNWNSFGLRYGRRQVARAARG
Protein: Uncharacterized protein (P96391)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Transmembrane protein
- tRNA
- NYN domain-containing protein
- Phosphoenolpyruvate carboxykinase
Sequence:
MRGQGHQIFVDELARFATSSADQRVVAIAQRAAEPLRVAVRGRPGVGCRTVARALQGAGSSSGMTVTPQARAADSDVDLVVYVTVEVVKPEDREAIAATRRPVVAVLNKADLAGPLSGAGPIVMAQARCAQFSTLLGVPMESMIGLLAVAALDDLDDTLRAVLRALAAHPDGFDALDRAVAGFLAAALPVPTEVRLRLLDTLDLFGIALGMAAFRPGRPSRTPAQLRTLLRRVSGVDAVIDKVTAAGSEVRYRRLLDAVAELEALAAQAKEIGGPIGEFLRDDDTVLARMAAAVDVALAVGLDVGPLDDPAAHLPRAVRWHRYSLDNGDMHRTCGADIARGSLRLWSLAGGMPLHRYRKSS
Protein: Dolichol phosphate-mannose biosynthesis regulatory protein (Dolichol-phosphate mannose synthase subunit 2) (DPM synthase subunit 2) (O94777)
Organism: Homo sapiens (Human)
Function: Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the GPI-GNT complex.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- Dolichol-phosphate mannosyltransferase subunit 1
- Dolichol-phosphate mannosyltransferase subunit 3
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit H
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit P
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit A
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
- Dolichol kinase
- N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
Sequence:
MATGTDQVVGLGLVAVSLIIFTYYTAWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGLLLLLFVGLFISYVMLKTKRVTKKAQ
Protein: Probable ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (O60139)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Acts late in the proteolytic pathway in conjunction with the 26S proteasome. Plays a role in avoiding DNA overreplication (By similarity).
Subcellular location: Cytoplasm. Endosome.
Interaction partners:
- AMSH-like protease sst2
- Ubiquitin thioesterase otu2
- Polyubiquitin
- Putative ubiquitin thioesterase otu1
- Probable ubiquitin carboxyl-terminal hydrolase 2
- Probable ubiquitin carboxyl-terminal hydrolase 1
- Vacuolar-sorting protein snf7
- Class E vacuolar protein-sorting machinery protein hse1
- Probable ubiquitin carboxyl-terminal hydrolase 7
- AN1-type zinc finger protein C1271.05c
Sequence:
MSDDYFDRLFELAFVYINEDETIQSCSFRGQRWLEEAQTLEQKNSLLKAYYYYLKALKLAYEIPCRFEISVKSTHYGEFKQFQKLAIQAVSKAFTIKSKLAVKHYLPVIQISDALSLSKKSSLKVLFLNFYSQESSKGYVFSKHTIAIPISCLQSMDSSKIYDFLKSAPFHPSMVICYSLERYFEDVSLAYKLYSMLRSLKLDPHFMELANPKKVDSSLSYENYQPIGLTNLGNTCYMNCVLQCLFACKDLTIPMLQGRGLLQNINTKNPLGTGGKITSAFFSLLQSVLLNHGQRSISPRNFLEIVQSLNRDFSIDGQCDAQEFLNFFLDKLHEDLNSNASRSPIAPLTEDQLSAREELPLSHFSHIEWNLHLRSNKSIVVNNFVGQLCSRTQCMTCGRTSTTFAPFTSLAIPIDDVSHVVSLQECLLKFSAPELLQGHDGWHCPVCKVQRSAKKVIMISKLPEYLIIQIQRFKISVMGRKKIDTPLGLSLQIPSKMLVPPSFQSGIGYIPSNYNLFAFICHYGQLENGHYISDVLFNNEWCHIDDSIVRTVGGITDLREDFSSSYILFYKRSSLLEEFEDKCPKMTLKRNVK
Protein: Ribonuclease P protein component 4 (RNase P component 4) (EC 3.1.26.5) (Rpp21) (O59248)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Binds RNase P RNA.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00757}.
Interaction partners:
- Ribonuclease P protein component 2
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS4
- Endoribonuclease Nob1
- Ribonuclease P protein component 1
- Ribonuclease P protein component 3
- Small ribosomal subunit protein uS11
- Large ribosomal subunit protein eL8
- tRNA-splicing ligase RtcB
Sequence:
MVDIVKRRDWEKKEKKKIAIERIDTLFTLAERVARYSPDLAKRYVELALEIQKKAKVKIPRKWKRRYCKRCHTFLIPGVNARVRLRTKRMPHVVITCLECGYIMRYPYLREVKQKRKKAT
Protein: Semenogelin-1 (Cancer/testis antigen 103) (Semenogelin I) (SGI) [Cleaved into: Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein] (P04279)
Organism: Homo sapiens (Human)
Function: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.
Subcellular location: Secreted.
Interaction partners:
- Lactotransferrin
- Eppin
- Clusterin
- WAP four-disulfide core domain protein 12
- Semenogelin-2
- Prostate-specific antigen
- Elafin
Sequence:
MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT
Protein: Beta-glucan synthesis-associated protein KRE6 (Killer toxin-resistance protein 6) (P32486)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the synthesis of (1->6)- and (1->3)-beta-D-glucan polymers of the yeast cell wall in vivo. It is required for full activity of beta-glucan synthase in vitro. May be involved in the maturation and transport of cell wall proteins (CWP) to the cell wall. May act as a transglucosidase and contribute to the construction of a protein-bound glucan-structure that acts as an acceptor site for the addition of (1->6)-beta-D-glucan at the cell surface.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:12237851}; Single-pass type II membrane protein {ECO:0000269|PubMed:12237851}.
Interaction partners:
- Cell wall synthesis protein KRE9
- Beta-1,6-glucan synthesis-associated protein KEG1
- Killer toxin-resistance protein 5
- Protein ROT1
- Protein KRE1
- 1,3-beta-glucanosyltransferase GAS1
- Cell wall synthesis protein KNH1
- 1,3-beta-glucan synthase component FKS1
- Glucosidase 2 subunit alpha
- Chitin synthase 3
Sequence:
MPLRNLTETHNFSSTNLDTDGTGDDHDGAPLSSSPSFGQQNDNSTNDNAGLTNPFMGSDEESNARDGESLSSSVHYQPQGSDSSLLHDNSRLDLSQNKGVSDYKGYYSRNNSRAVSTANDNSFLQPPHRAIASSPSLNSNLSKNDILSPPEFDRYPLVGSRVTSMTQLNHHGRSPTSSPGNESSASFSSNPFLGEQDFSPFGGYPASSFPLMIDEKEEDDYLHNPDPEEEARLDRRRFIDDFKYMDKRSASGLAGVLLLFLAAIFIFIVLPALTFTGAIDHESNTEEVTYLTQYQYPQLSAIRTSLVDPDTPDTAKTREAMDGSKWELVFSDEFNAEGRTFYDGDDPYWTAPDVHYDATKDLEWYSPDASTTVNGTLQLRMDAFKNHGLYYRSGMLQSWNKVCFTQGALEISANLPNYGRVSGLWPGLWTMGNLGRPGYLASTQGVWPYSYESCDAGITPNQSSPDGISYLPGQKLSICTCDGEDHPNQGVGRGAPEIDVLEGETDTKIGVGIASQSLQIAPFDIWYMPDYDFIEVYNFTTTTMNTYAGGPFQQAVSAVSTLNVTWYEFGEYGGYFQKYAIEYLNDDDNGYIRWFVGDTPTYTIHAKALHPDGNIGWRRISKEPMSIILNLGISNNWAYIDWQYIFFPVVMSIDYVRIYQPSNAISVTCDPSDYPTYDYIQSHLNAFQNANLTTWEDAGYTFPKNILTGKCTSSKFKLSS
Protein: Transporter (Q1WGB5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Tryptophan hydroxylase 1b.
- 5-hydroxytryptamine
- Tryptophan hydroxylase 1
- Amine oxidase [flavin-containing]
- 5-hydroxytryptamine
- 5-hydroxytryptamine
- Tryptophan hydroxylase 2
- Novel protein similar to vertebrate urocortin 3
- SERTA domain-containing 4
- Protein FEV
Sequence:
MDMKESMMMNQEYGGEQQKVPESQENGRLVVDSVPEKDQKSGSGPGQVSNGYRSTSPQSPKEGAGTGTDRVNTPGTFRTLVVQQTSLDPPRETWSKKMDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYLLMAVFGGVPLFYMELALGQFHRSGCISIWKHVCPIFKGIGFAICIIALYIAFYYNTIMAWALYYLLSSFRATLPWTTCNNRWNTPNCTHYLSTDLNVSWTNNSISPAEEFYVRQVLQVHLSPGLHQLGWVSWQLALCLLFIFTVVYFSIWKGVKTSGKVVWVTATFPYLVLLILLIRGATLPGAWRGVVFYLKPDWKKLLTTTVWLDAAAQIFFSLGPGFGVLLAFASYNPFHNNCYKDALITSSVNCLTSFLSGFVIFTVLGYMAEMRQQGVETVAKDAGPSLLFIIYAEAIANMPAATFFAIIFFLMIIMLGLDSTFAGLEGVITAMLDEFPHLLARRREWFVLGLVCVCYLGALSTLTYGGAFVVKLFEEYATGPAVITVVFLEVIAVSWFYGTTRFCNDVQLMLGFAPGLFWRVCWIAICPCFLLFIIVSFLAFPPEVKLFDYLYPFWTTVLGYCIGVSSFICVPSYMVYHLVTTKGTFQQRLLKGITPEAPGSSGPQRDTIVITNAV
Protein: Baculoviral IAP repeat-containing 5b (Baculoviral IAP repeat-containing protein 5b) (Survivin 2) (Q90WU8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}.
Interaction partners:
Sequence:
MYSYEKRLQTFSEWPFREDCQCTPELMAKAGFVHCPSENEPDVACCFYCLRELEGWEPDDNPWSEHAKRSPNCAFLHMSKTFDELTAIEYFHLEQERLRIYIKKMGHRKIAYFRDEVEATSKNLRALI
Protein: Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (OsNHX1) (Q9SXJ8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Vacuolar antiporter that acts in low affinity electroneutral exchange of protons H(+) for cations such as Na(+) or K(+) across membranes. Plays important roles in the transport of Na(+) and K(+) accumulated in the cytoplasm into vacuoles, and is involved in salt stress tolerance.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:14988485}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGMEVAAARLGALYTTSDYASVVSINLFVALLCACIVLGHLLEENRWVNESITALIIGLCTGVVILLMTKGKSSHLFVFSEDLFFIYLLPPIIFNAGFQVKKKQFFRNFMTITLFGAVGTMISFFTISIAAIAIFSRMNIGTLDVGDFLAIGAIFSATDSVCTLQVLNQDETPFLYSLVFGEGVVNDATSIVLFNALQNFDLVHIDAAVVLKFLGNFFYLFLSSTFLGVFAGLLSAYIIKKLYIGRHSTDREVALMMLMAYLSYMLAELLDLSGILTVFFCGIVMSHYTWHNVTESSRVTTKHAFATLSFIAETFLFLYVGMDALDIEKWEFASDRPGKSIGISSILLGLVLIGRAAFVFPLSFLSNLTKKAPNEKITWRQQVVIWWAGLMRGAVSIALAYNKFTRSGHTQLHGNAIMITSTITVVLFSTMVFGMMTKPLIRLLLPASGHPVTSEPSSPKSLHSPLLTSMQGSDLESTTNIVRPSSLRMLLTKPTHTVHYYWRKFDDALMRPMFGGRGFVPFSPGSPTEQSHGGR