wanglab/gogpt-training-data huggingface dataset:
Protein: Kakapo (Q7KAJ2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MMDRESLSEWAKDKPLSILQLDPADRAVLRIADERDAIQKKTFTKWVNKHLKKANRRVVDLFEDLRDGHNLLSLLEVLSGEHLPREKGKMRFHMLQNAQMALDFLRYKKIKLVNIRAEDIVDGNPKLTLGLIWTIILHFQISDIVVGKEDNVSAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPPSIHPLFDMESQRRVHEYRDLAQQFIYWCHEKTAYLQERSFPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQIYKELERYFETVGEVDVEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKVQREIKHVDQKLTDLEARIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQDMNQDCHVLNEGRYPHVSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKYPVHETTVTRQTRMVVESRQIDTNPHFRDLQEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELALYQQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWADKQLDLPSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQSDFGLDQGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRRQPVNRQGPVQAICAYKQQGQLQIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKLLSEGDPNDPQLRRLRREMDEVNRLFDEFEKRARAEEESKQASRIFTEECLSIKSKLEDMARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTPVLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELARHQDLPSTAEGLQQVFKQLNHMQDIITQQQPQMDKMNDAADQLGRMGVPTKVLGDLKRLHSNVERLNTRWSAVCNQLGERMRSCETAIGLMKNLQSSVQVEESWVDGTTERLSAMPTATSAYELDKLLGAAIERKPKIENVNVAGGRLIREAKIYDSKCLRFVDWLVEARPSFSPPRRDLRPADSDPGATQYYSQRLDNLNTKYDRLLEQLSQRLKTAIEVNGSDGLQYAESLQKPLKTFRVDFSAGSLPTGDGYAARQEDLYTTTYSTTQISSTKTTKSSTKSVYSSDGLDAASQDVSTASLPQSQIQFNEIRTLKRSQQLGGHSVLDIAGIRDPRTGRVLTIGEAIQLRILDVRTGEMLVGDRRITLEQAADQGLIDLQLAKQLLEPGAGRDASGRELSLLEVIQREISEAESGYETAEKRIKQAVFEKFNMCEENVNDLLKWVTTVEQKISSVGGPREKIDELRNQINALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRVDRVNDRTVRLLRRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVSLVSAQYKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPMEINQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGVQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASASNARIAKKVESNLNDVTGKFEKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALIRPESPARKRSTYSPIKRTSPLRRMSGDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLSELSPVQQQLSEINNRYGLIGVRLNDRQHELDNLNEELRKQYENLKGL
Protein: Protein NBA1 (NAP1 and bud neck-associated protein 1) (Q08229)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Bud neck {ECO:0000269|PubMed:18086883}. Cytoplasm {ECO:0000269|PubMed:14562095}. Note=Assembles at the inner surface of the cell membrane. Localizes to the septin cortex prior to bud emergence and to actin cap in unbudded cells. {ECO:0000269|PubMed:18086883}.
Interaction partners:
- Altered inheritance of mitochondria protein 44
- Protein NIS1
- Nucleosome assembly protein
- Bud site selection protein RAX2
- Bud site selection protein RAX1
- BEM1-interacting protein 1
- Protein BNI1
Sequence:
MSEEREENGISRATLNTQRLSAMIDSLNNEKDDRLFPSPTTTRTMITEEKADQSDVFKPPSRLLRSPAGDVSLPPGDNRSSMISNYSGIIQEGVEVSYVVKNRQQTQERRTSKDSNSLYSLKEPVSKNELPSLPMLPSEATLTKHLSDNQSTKSNTNADEIVIKPVTNAKPVGRFNSNTSKKVEGRGSLKLLSSPLRQEKVMRSSIGSGNLASESGSSTYNTKFHQSIQEQLEEEEEGNVSDKLSIVSSVIPELYTTTNEAPKAINPIRSETNDYNPTIPPRSKDRPRSRLFIEEGDGEGDLLTEEILPTPVQPGGHYKNSSQISTVSEQKSESYYSAATSMPPEEETYLTRPLPSTPNEDSRVTSNLKRDDTLKAIHDRANHTSTSTNKQDDDMYEDIIEETPKKTKLKKDTKKKLNKKKSVKELRSFDIDTLNQLLSVTKGTLIGSEFAQLGMKIEEKRALERLVDSLSRLTADMVLDPDRYEEGLKRLDKATKALEGF
Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma (EC 3.1.4.11) (Q9VXH3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Growth factor receptor-bound protein 2
- phosphatidylinositol 3-kinase
- DShc protein
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Kinase
- EG:86E4.5 protein
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- Kinase
- Diacylglycerol kinase
- inositol-polyphosphate 5-phosphatase
Sequence:
MSCFSAMSAPLLGEMEQTIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRLFADDCQRFESSKCFVILHGNHFKLKSFSVVALSEIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKDFKLFLAGVSCKMTTGKFMEHFTEDVRRKHDLKFDDFSRLYQKLLLPNGFASVLSGSGVANFPYSEDQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSKYDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCSLEQQRNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEENVTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVIDSTTEDYNSLNEEGTDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSWIFQEMSSFPETKAEKQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNPNNPLCDGLSEVKVSIRLIAARHLFRGGKSNNPQIVVELIGASFDTGVKYRTKVNENGFNPVWNESCEFNVRNPQFAILRFEVQDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIANVTAP
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A0A8I6AHN7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEDEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHAQQPPPPQQQDRSKPSYHAPEPKPHYDPADRAREVEDRFRKTNHSSPEAQAKQTGRGLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAAKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQSTVDQKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTANETQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGLRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCTIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
Protein: KappaPI-actitoxin-Ael3a (KappaPI-AITX-Ael3a) (Kunitz-type serine protease inhibitor APEKTx1) (P86862)
Organism: Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima)
Function: Dual-function toxin that inhibits both serine proteases (trypsin Kd=124 nM) and voltage-gated potassium channels rKv1.1/KCNA1 (IC(50)=0.9 nM). The activity on the Kv1.1/KCNA1 is selective and reversible. The toxin presumably acts by blocking the channel pore in the open state.
Subcellular location: Secreted {ECO:0000305|PubMed:21477583}. Nematocyst {ECO:0000305}.
Interaction partners:
Sequence:
INSICLLPKKQGFCRARFPRFYYNSSTRRCEMFYYGGCGGNANNFNTLEECEKVCLGYGEAWKAP
Protein: WD repeat-containing protein YPL247C (Q12523)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Dual specificity protein kinase YAK1
- Inhibitor of glycogen debranching 1
Sequence:
MDPFHNGNKRSSISFGSSQRQPYNKNNYLSGTNGPSSAAQDQGRGPSPFGMSGNTTNGGNSKRNSGCDLSATYYASRSPMYSPLDFSPPVFSPNHSQLQQARGYAANIPVVSNLMNPSMASVCEYQSHYPLFGLDWSADDYVCLGSYKEDSRNKLQVLHSNDLLSWESVVDADVVYPVSKIQWVPSQLYPRKLATCSDSLRIWSVSPEERQFQEQINLSLCKYNRQHPANPAAADDMKVIGTFPPITSFDWNTVDTNLIISSSIDTTCIVWDLQSSHYVKTQLIAHDSEVFDVRFLTKSTQLFASCGGDGSVRVFDLRSLAHSTIIYEPPSSSVSGATAGTITPSSKGSDALLRLEPSPYDPNVLATFAADSNKIIILDMRNPESPILNLQGHGSSVNGIKWHPTKRNVLLSCGDDCQVLYWDLNSSFMEINAAGSKSPSIHGTSLEDPDGDTEMTDGGAGSGLNEDPLSLNNNSKQVCKTLETPNMMYANKTQEINNIAWRPQRGDWFGCVSGKKFQNVRVL
Protein: Bazooka, isoform B (Q0KHR3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Atypical protein kinase C
- LD29223p
- Inscuteable
- Cdc42 homolog
- LD33695p
- DE-cadherin
- Protein crumbs
- Protein PALS1
- Protein numb
- G protein alpha i subunit subunit alpha 65A)
Sequence:
MFDVPPKCPALANKLGGLFGWRHTYKVAAKQEGIPHGQLHKSYSLTLPKRPPSPSTYSCVKPDSWVTVTHLQTQSGILDPDDCVRDVADDREQILAHFDDPGPDPGVPQGGGDGASGSSSVGTGSPDIFRDPTNTEAPTCPRDLSTPHIEVTSTTSGPMAGLGVGLMVRRSSDPNLLASLKAEGSNKRWSAAAPHYAGGDSPERLFLDKAGGQLSPQWEEDDDPSHQLKEQLLHQQQPHAANGGSSSGNHQPFARSGRLSMQFLGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQNGAYSSKSLPRESKRKEPLGQAYESIREKDGEMLLIINEYGSPLGLTALPDKEHGGGLLVQHVEPGSRAERGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSELRVRVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDSLPPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGRKILRSASSSDILDHSNSHSHSHSNSSGGSNSNGSGNNNNSSSNASDNSGATVIYLSPEKREQRCNGGGGGGSAGNEMNRWSNPVLDRLTGGICSSNSAQPSSQQSHQQQPHPSQQQQQQRRLPAAPVCSSAALRNESYYMATNDNWSPAQMHLMTAHGNTALLIEDDAEPMSPTLPARPHDGQHCNTSSANPSQNLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETNSGVEHFSRDALGRRSISEKHHAALDARETGTYQRNKKLREERERERRIQLTKSAVYGGSIESLTARIASANAQFSGYKHAKTASSIEQRETQQQLAAAEAEARDQLGDLGPSLGMKKSSSLESLQTMVQELQMSDEPRGHQALRAPRGRGREDSLRAAVVSEPDASKPRKTWLLEDGDHEGGFASQRNGPFQSSLNDGKHGCKSSRAKKPSILRGIGHMFRFGKNRKDGVVPVDNYAVNISPPTSVVSTATSPQLQQQQQQQLQQHQQQQQIPTAALAALERNGKPPAYQPPPPLPAPNGVGSNGIHQNDIFNHRYQHYANYEDLHQQHQQHQISGGDSTTSISETLSESTLECMRQQVIRQRIKVEAESRRHQHYHSQRSARSQDVSMHSTSSGSQPGSLAQPQAQSNGVRPMSSYYEYETVQQQRVGSIKHSHSSSATSSSSSPINVPHWKAAAMNGYSPASLNSSARSRGPFVTQVTIREQSSGGIPAHLLQQHQQQQLQQQQPTYQTVQKMSGPSQYGSAAGSQPHASKV
Protein: RING-H2 finger protein ATL65 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ATL65) (Q67YI6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MRFVAPPPRSGDNSPSPSPSSGISEEILSRSSDPPLEFSPPLIAMVVVLAAAFLFVTYSRLISRRFLSPLFRRFRRWRCRRRRLLHLSSASSASTSSSDLRSFSPFPFDSFHYSSYSPYGLDDSVIKTLPLFLYSAAACTGKPAVGKTSAANCRDCAVCLLEFEEGDYVRTLPLCFHAFHLECIDEWLRSHPNCPLCRTAILGSAGVLTPMSPFVPLMAPRIRPSLDDEENNAIIIRGEITPSRSNWNTIAADTTNDQEIRASVEEQSSPAISRFRELKRSYSFECERESESERVTMEPATVSPWRYRRSTWNKRQSPFGNLISKSRVFSFRYYRSTKSPFFRRRSSAGVFYPISERIPATGSSSRRTKSMTSPMFFRTAPHSSSRLRCGDPEALLSPERWRRRDTCRAEM
Protein: Protein MICRORCHIDIA 2 (AtMORC2) (EC 3.6.-.-) (Protein CRT1-homolog 1) (CRT1-h1) (Q5FV35)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediator of defense signaling triggered by distinct classes of R proteins. Required during hypersensitive response (HR) that confers disease resistance to turnip crinkle virus (TCV). Contributes to resistance against Pseudomonas syringae and Hyaloperonospora arabidopsidis, at early stages prior to cytosolic calcium ions Ca(2+) accumulation. Required for pathogen-associated molecular pattern (PAMP)-triggered immunity, basal resistance, non-host resistance and systemic acquired resistance (SAR). Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. May also be involved in the regulation of chromatin architecture to maintain gene silencing. Exhibits ATPase activity (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q84WV6, ECO:0000255|PROSITE-ProRule:PRU00768}. Endosome {ECO:0000250|UniProtKB:Q84WV6}. Note=Present in nuclear bodies near chromocenters. Localized in endosome-like vesicles displaying rapid cytosolic streaming. Accumulates in the nucleus following pathogen-associated molecular pattern (PAMP) treatment or infection with an avirulent pathogen. {ECO:0000250|UniProtKB:Q84WV6}.
Interaction partners:
- Histone-lysine N-methyltransferase family member SUVH9
- Histone-lysine N-methyltransferase family member SUVH2
- AT-hook motif nuclear-localized protein 10
- Protein DEFECTIVE IN MERISTEM SILENCING 3
- SWI/SNF complex subunit SWI3D
- Protein INVOLVED IN DE NOVO 2
- AT-hook motif nuclear-localized protein 16
- SWI/SNF complex subunit SWI3C
Sequence:
MPPMAKNAAVTDVVHLDSDSDSDNGVVGGRESASTIAGAATMAPRETLECRSFWKAGDYFVIPNVVTPTAPGMLEHARVHPRFLHSNATSHKWAFGAIAELLDNAVDEIQNGATFVKIDKINIVKDNSPALVFQDDGGGMDPAGLRKCMSLGYSSKKSNTTIGQYGNGFKTSTMRLGADAIVFSRSTRGGTSTQSVGILSYTFLRKTGQDDVTVPMIDIDISKERPQPIIYGSPEDWAANLEILLKWSPFSTEDELLQQFEDVGTHGTKVIIYNLWLNDEGIYELSFDDDEEDIRLRDESVNDGKRLHHKILELRSHISYHLRYSLRAYASMLYLKKFKNFKIIIRGIPVEQFNIADGFRFPEIIKYKPHTATTEQASTEIKIGFVKEAPKLAICGFNVYHKNRLIRPFWKVTMGGDSTGHGVVGVLEANFIEPAHDKQDFERSSLFQRLEARLKKIVYSYWYSHCHLLGYHKYQMPADKSKKIAIPDQPPTISTVNPSPLPSDKISQGGPIIREINLSNATSSRTVAFASPHLRNSTGLRSNFQPVQLNPQPTAADTGNNLDGKSAGEIRQENLQLFMRCEEYIKKENETEQTVKSLEKELEEFKSKCAHLALLVDAKKKEMQQA
Protein: Kallikrein-11 (EC 3.4.21.-) (Hippostasin) (Serine protease 20) (Q9QYN3)
Organism: Mus musculus (Mouse)
Function: Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin (By similarity).
Subcellular location: Secreted.
Interaction partners:
- Cytokine receptor-like factor 2
- Thymic stromal lymphopoietin
- Interleukin-7 receptor subunit alpha
Sequence:
MRRLKSDWKLSTETREPGARPALLQARMILRLIALALVTGHVGGETRIIKGYECRPHSQPWQVALFQKTRLLCGATLIAPKWLLTAAHCRKPHYVILLGEHNLEKTDGCEQRRMATESFPHPDFNNSLPNKDHRNDIMLVKMSSPVFFTRAVQPLTLSPHCVAAGTSCLISGWGTTSSPQLRLPHSLRCANVSIIEHKECEKAYPGNITDTMLCASVRKEGKDSCQGDSGGPLVCNGSLQGIISWGQDPCAVTRKPGVYTKVCKYFNWIHEVMRNN
Protein: RIC3 acetylcholine receptor chaperone, isoform C (RIC3 acetylcholine receptor chaperone, isoform G) (RIC3 acetylcholine receptor chaperone, isoform S) (Q9W2N4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}.
Interaction partners:
- Protein unc-50 homolog
- Nicotinic acetylcholine receptor alpha6, isoform E
- Nicotinic acetylcholine receptor alpha7, isoform E
- Nicotinic acetylcholine receptor alpha5, isoform I
- Wing blister, isoform B
- Acetylcholine receptor subunit alpha-like 2
Sequence:
MPATATSKPRAPLVEEGMTPKKTALIIVTVIGCIAILWPKVFHPMMFGGVPPSQPNFKDPRAAPGGCCDVVLDREQFLNATKKDTVEPFGPHLYRKQINVYTGEISLRQERPAHLHPESIYQAMRERGRAIPATPTVPILERKTSPSNPPPRIVDGRPGPIPGMRPPMGAGALHQPQQRGSSMGFLMPLYTIGIVVFFGYTLMKIMFKKQVPNDPYGAAPPNPAFRQEVFGSQNHSQVEDLGGSKLGAATATAAAKKPAAKDTEKELYNASVSATEVASSLSASLKSHQQLKEAEQLMEIEKLRQKLESTERAMAQLVAEMNTDQYEAKKNDNEKTREQPLDKQNLSNGHASSTDQNPEQETVAKGARKRRDLSAEQELTVLGMELTASCEGGHKWTGRPPTPVFRAPSEHSKLEDNLPEPQSIYLEGALAHESQILVADSQIKREEVYDSELNGSAEEPAIILSSRMTLSLINLDANQQNGNAGKSAVESPLADDIEIIGHDEQ
Protein: 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (EC 2.3.1.51) (Lysophosphatidic acid acyltransferase A) (LPA acyltransferase) (LPAAT) (Q9I7C1)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Phosphatidate cytidylyltransferase
- Glycerol-3-phosphate acyltransferase
- Glycerol-3-phosphate acyltransferase
- Probable phosphatidate cytidylyltransferase
- Diacylglycerol kinase
- Glycerol-3-phosphate dehydrogenase [NAD
- D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase
- Probable FAD-dependent glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate dehydrogenase
Sequence:
MSTVQAIRTVLFYLLLSASAFVWGTLSFFIAPILPFRARYRFVVQNWCRFAIWLTRVVAGIRYEVRGLENIPEKPCVILSKHQSTWETFFLSGFFEPLSQVLKRELLYVPFFGWALALLKPIAIDRSQPKLALKQLAKQGDECLKKGAWVLIFPEGTRIPVGQMGKFSRGGTALAVNAGLPVLPIAHNAGQYWPKAGWAKYPGTIQVVIGPAMHAEGEGPRAIAELNQRAEAWVSETMAEISPIQQRVSHPEPSVVS
Protein: CUB and LDLa domain, isoform C (Q8IQA8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLAEALGYGYLLAYVICLLCWPGEAYPASSSYRDLDICNHWDGRRHFLELGSPAGEVHARNVTTTAYRSSPLVFKNDAVAGDVWYQCSLELVTCAECVIRVAFTYANFSKSCGNTGGKSSMCPCEHIQFSEPPYDSTISGQEFCGDGKVFRSKTRTLQLKFFYRASNAHVFSLQYFSERNVRIVSGSPKQSIVGNGSTKSQPQVISTPYFPMAYPRDYGIEHILTCEADNCQVRLDFTDFQLGLTSTLEIFDSNGQMLDSYTGEHFRPPITVSSGKSLLLQFRGNSATGVGFRAEVSFVSSKQLKDERLVPYTDCGGMVTGPGGAITMMNMIENATDVRLFDCIWIIKPGNNYMMMKTHISLRVDDFYGMAARSELTIRQGTTSDAVEIENVMWPNNGLSKESHVAPILNGYYIRLRGVFGMSSKLAIVYSVFNYLNCYIGSEFLCGNNHCISIRLHCDGFDHCGDGSDEPDSCEEDWAHLHHDRRWYSHKPNYYFPKIDQYPDLKTATGIFIISTLGIFGVLSGWMVILYRMGVRARHQRELQSHLQTISELLDRQDEDRTPDEPPSYEAPPDYEEVIKVGMQQELREPRRQRRARRAPPRDRSCSRAASNCTVQSVLPLHRSCTLERDQEQPSTSAAAMTHAVAATDTTEDAEHVQTMAQRMLLATAICGRSRVPPIPPCSR
Protein: Paternally expressed 10 (A0A087WX23)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRNKRVLKTKKRRSGRGGQDPGLHPHRSEATAGRSPPTPTVTLGPDCPPPPPPPPPNNNNNNNSKHTGHKSACVPNMTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERRLARAAAARKPRSPPRALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSSPGKLPGPAVEGPSATGPEIIRSPQDDASSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHVYPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQVLQVKRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTYAAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSYSTL
Protein: WD repeat-containing protein LWD2 (Protein ANTHOCYANIN 11-B) (AtAN11-B) (Protein LIGHT-REGULATED WD2) (WD repeat-containing protein AN11-B) (Q38960)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Clock protein essential for the proper expression phase and period length of both the oscillator and output genes known to participate in photoperiod sensing. Required for the expression of APRR9, APRR7, and APRR5. Regulated by APRR9 and APRR7 at the transcriptional level, indicating the existence of a positive feedback loop within the circadian clock.
Interaction partners:
- Pentatricopeptide repeat-containing protein At3g26630
- Transcription factor TCP22
- Protein REVEILLE 6
- Protein REVEILLE 8
- Protein LNK2
- Protein REVEILLE 4
- Protein CCA1
- Protein LHY
- Dual specificity protein kinase YAK1 homolog
- Protein LNK1
Sequence:
MVTSSDQIQNGSEEQSKRSEIYTYEAPWQIYAMNWSIRRDKKYRLAITSLIEQYPNRVEIVQLDESNGEIRSDPNLCFEHPYPPTKTSFIPDKECQRPDLLATSSDFLRLWRISDDESRVELKSCLSSDKNSEFSGPITSFDWNEAEPRRIGTSSIDTTCTIWDIEREVVDTQLIAHDKEVYDIAWGGVGVFASVSEDGSVRVFDLRDKEHSTIIYESGEPSTPLVRLSWNKQDPRYMATVIMGSAKIVVLDIRFPALPVVELQRHQASVNAIAWAPHSSSHICSAGDDSQALIWDISSMGQHVEGGLDPILAYTAGAEVEQLQWSSSQPDWVAIAFSNKLQILRV
Protein: Bacterial bifunctional deaminase-reductase C-terminal domain-containing protein (P71968)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Riboflavin biosynthesis protein RibBA
- Dihydrofolate synthase/folylpolyglutamate synthase
- 3,4-dihydroxy-2-butanone-4-phosphate synthase
- 6,7-dimethyl-8-ribityllumazine synthase
- Alpha-
- Riboflavin biosynthesis protein
- Riboflavin synthase
- Cell division protein ZapE
- Dihydrofolate reductase
- Possible secreted protease
Sequence:
MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT
Protein: Kallikrein 1-related peptidase b26 (EC 3.4.21.35) (Glandular kallikrein K26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2) (Tissue kallikrein 26) (P36369)
Organism: Mus musculus (Mouse)
Function: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Interaction partners:
Sequence:
MWFLILFPALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTTPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSTCLASGWGSITPTRWQKSDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCAGDSGGPLICDGILQGTTSNGPEPCGKPGVPAIYTNLIKFNSWIKDTMMKNA
Protein: Actin-depolymerizing factor 10 (ADF-10) (AtADF10) (Q9LQ81)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O49606}.
Interaction partners:
- Profilin-1
- Profilin-2
- Profilin-3
- Profilin-5
- Profilin-4
- Cyclase-associated protein 1
- Villin-5
- Villin-1
- Protein phosphatase EYA
- Fimbrin-5
Sequence:
MANSASGMHVSDECKLKFLELKAKRNYRFIVFKIDEKAQQVMIDKLGNPEETYEDFTRSIPEDECRYAVYDYDFTTPENCQKSKIFFIAWSPDTSRVRSKMLYASSKDRFKRELDGIQVELQATDPSEMSLDIIKGRVNL
Protein: C-X-C chemokine receptor type 4-A (CXC-R4-A) (CXCR-4-A) (xCXCR4) (Stromal cell-derived factor 1 receptor A) (SDF-1 receptor A) (Q9YGC3)
Organism: Xenopus laevis (African clawed frog)
Function: Receptor for the C-X-C chemokine cxcl12/sdf-1. Transduces a signal by increasing the intracellular level of calcium ions. Signaling with cxcl12/sdf-1 mediates the directional movement of mesodermal cells during gastrulation. May play a role in the migration of embryonic presumptive primordial germ cells (pPGCs). May also be involved in regulating the migration of hematopoietic stem cells into the larval liver.
Subcellular location: Cell membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:15740585}. Nucleus {ECO:0000269|PubMed:15740585}. Early endosome {ECO:0000250}. Late endosome {ECO:0000250}. Lysosome {ECO:0000250}. Note=Expressed in the cytoplasm of a small number of embryonic pPGCs from stage 24. Expressed in the nucleus of 3 lateral pPGCs. {ECO:0000255, ECO:0000269|PubMed:15740585}.
Interaction partners:
Sequence:
MDGFSGGIDINIFDGNSTENGSGDFEDFIEPCFMHENSDFNRIFLPTIYSFIFLLGIIGNGLVVVVMGYQKKSRTMTDKYRLHLSVADLLFVFTLPFWSVDAAIGWYFKEFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQGSRKMLADKVVYAGVWLPALLLTVPDLVFARVSDENGQFVCDRIYPIENRETWTVGFRFLHITVGLILPGLIILICYCVIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYVCLTTDTFMLLGLVKGDCIWENTLHMAISITEALAFFHCCLNPILYAFLGAKFKTSAQNAFTSVSRGSSLKILSKKRAGLSSVSTESESSSFHSS
Protein: Cullin 2 (A0A8I6A9D2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYAETKIFLENHVRHLYKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQYIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQNILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQGIFVSPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHSECHSIIRHERKNDMANMYVLLRAVSSGLPHMIEELQRHIHDEGLRATSNLTQEHMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDKLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLNNKFNNFIRNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKELEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA
Protein: Argonaut-like protein (Q7KWS3)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MGPKKPNIQDEPNQPNPAGGVKPPPGFQQQPQHQQQQQQPRGPPPGFQQQQQPQQQQQQQPQQQQQQQQPRGPPPGFHQQGHPQGHPQGQQQGHPQQGQQQRGPQQQGQQQGNPQQQQRGPQQGHPQQQQRGPQQGHPQQGHPQQGQQQQRGPQQGQQQGQQQQRGPQQGPQQGQPKQPSGSWGKQPPQNLQPQQQPQQQQQQQQQQQTTTTTTTTTSSSSPAAAQVPTISRKDLVKDDDIENIAIVPAKPRSIQSQPISVITNFFPVQVRQNRSLFLYRIDYDPPQVARDRRFKVMKEFLAANSLIFTKYDGDSLLFSAKKIQINSQNVDGVQILIKLAKEFDHTDKSITQFFNVLTKSFMRSMGYSLMGRNYYTSVGKRDVPKHFLEVWKGFSTSVIPTEAGTMLLCDSTTKVVRSQTVLERIRYLNNNTNRCTAEIVNSIVLTRYNNKTYRISGISWQGKNSKVTDIMEGSTTFLQYYQKNYPKYKITDLNQPLLKSEVKMRGMKQTIYLVPELTYLTGLNDEMRKDFHIMKDLAEESNVEPYKRIDNLNNFVNGFNTNPTISKELESWGISYQPALKVEGCVLQAPKNVPINNANALRNVKWVFIVEQLDFQRGECQKNLDLFLRESQLQPPTIHHPVLPKSSRDIKSTIYTDIMEQYVKKGVSFFLIIIPQNNAEVYKGIKMKSLIQFRVLTQCIFSRTFDKGRPVSVKLKQQVVAKLGLAPWGLGQDIYKGVPKKTMVIGVDVGHNSDMKGHSVVGFVATIDDKFQKFFSRAYAQERPGKEIIHSLEDATKEAMKSYFNHNNCLPELVIVYRDGVGDGMLDLVNKTEIAAMKKGFAETPSSWGTKPKLVYTIVKKNTNARFFTNDNQKANPPPGTLIDSKITHQNWYDFFLVSQVAFKGSINPTHYHVLLDEHQMAADLFQFFTFQMCHLYFNFEKSVRVPASCQFAHKMAFLIGRTVGRNVDKDLSDKLYFL