wanglab/gogpt-training-data huggingface dataset:
Protein: ATP-dependent RNA helicase ddx19 (EC 3.6.4.13) (ATP-dependent RNA helicase helC) (DEAD box protein 19) (Q54TF8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: ATP-binding RNA helicase required for normal differentiation and development.
Interaction partners:
- mRNA export factor GLE1
- Spore coat protein SP65
- Nuclear pore protein
- Pre-mRNA-processing-splicing factor 8 homolog
Sequence:
MSEKETNTTSTENKEKEKQEQTNTNSTTESTNNQVDEEYERPGRSEGLDEFGIQLDIQQSDPNSPLYSVKTFEELGLKPELLKGVYAMGYNKPSKIQEAALPIIIQSPNNLIAQSQSGTGKTAAFTLGMLNCVDPSINAPQAICISPTKELALQTFEVISKIGQFSNIKPLLYISEIEVPKNVTNQVIIGTPGKILENVIKKQLSVKFLKMVVLDEADFIVKMKNVPNQIAMINRLLPSNVKVCLFSATFSMGVEELIKKIVQDPYTSIRLKRQELSVEKIHQYFIDCGSEDNKALILSDIYGFISVGQSIVFVHTIATAKSVHQKMVDEGHSVSLLYGKDLTTEERFKQIKDFKDGKSKVLITTNVLARGIDIPQVSLVINYDVPLDEMGKPDPVHYLHRIGRVGRFGRSGVALSFVYDQQSTNKLMNISTHLGVPLKELKSSEIESLDGILKGIRNQLTPLNN
Protein: Tie-like receptor tyrosine kinase (EC 2.7.10.1) (Q9VZA8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Fibroblast growth factor
- DShc protein
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
- RAC serine/threonine-protein kinase
- E3 ubiquitin-protein ligase CBL
- Protein son of sevenless
- Adapter molecule Crk
- phosphatidylinositol 3-kinase
- Ras-like protein 1
- Growth factor receptor-bound protein 2
Sequence:
MCVSVCAKTNNRKPDRKSAEKTISQSSTARAATIILVLLFIFFSRYLVYASVTMSLMKIHRGNESFCSCWLLLLLLVALLLAEAIVAAAAATLSETQTNATNGAIREPPVQLQLQQQQLQLQLQLNATAGDGESRNSAEIFSPGDVDVVGDKPTTYRPSGANRPSIAPLNSAQDRERKLMNVLAARRTALHRGGFRTRIGTTGRTAISPSAAVESTSKAPSDPRSVCIRNCTKNFTRRTTASCMRQCANFTRMAMPSNGNSSVVLKGSASLKAAAPAGDRDTNEILFSDESSHGLFVVAKEQNGTLNHIADGTKPAVMGKGIPSKTNSMEDDVEEEEDELKPYVYFGAKLPPIRPGGLTIKAAEGDDDHPRVLEVSVAQSTTPTITTTSTTPAPVSSTRPTASTRRPLTPVERSRSKYKYHMRERGLVPTAAPPPAAPPAPPVSRTRYVGSGRPTAGLSDSIQDLKQTESEVAKPVVRRVVQKVSPSSSTPLIITVLSAEEETTVGQTEALPTDESTTTTSTTTTTEKPSTTTSTSTTTTTPVPSTSKRTTTNAPLSTTNTPTTTTSSTTPSTTTTSSTSTTVIPTTTKANSIIEKDKELIRALGPALTREINIDDANNLIVFCNNTSDCGVTPRTQTQPSHTTDSSPKILRTTVLTSIRSTVHPRPTSTSTTTSTTTTAPPAVTAPSNEVYIGIVESSSSASPADISSTVIANERDLNMEMRRMNLVTLVLVAVGVIPLAAIILYLVRNFVIRRRAKQSEVFDVCITDQQPISPVKKVDSKYQVDDDEDEVDHQHHQHMQHHQNHQNHQNHQHHQAMPMSQASQRDANHNRYGNNDDKTSLASEFHDFERSNIRLKSLLGEGNFGQVWKAEADDLSGHFGATRIVAVKTIRACSAQVSLKDEANIMRKLGSHQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSATNILPASVPGGRSLAPLSPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQLTGREVIRRVPQGLRPDLPKESRHEFYNLMSRCWHKEPHMRPSFAQSRLEITRSLHKWVDDDSAASDYMDVSGFSEDLEHGVVYFNHRISEFECEI
Protein: Interferon regulatory factor 7 (IRF-7) (Q92985)
Organism: Homo sapiens (Human)
Function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Induces transcription of ubiquitin hydrolase USP25 mRNA in response to lipopolysaccharide (LPS) or viral infection in a type I IFN-dependent manner (By similarity). Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. Exists in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization where along with other coactivators it can activate transcription of the type I IFN and ISG genes. Can also play a role in regulating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or through induction of IRF1. Binds to the Q promoter (Qp) of EBV nuclear antigen 1 a (EBNA1) and may play a role in the regulation of EBV latency. Can activate distinct gene expression programs in macrophages and regulate the anti-tumor properties of primary macrophages (By similarity).
Subcellular location: Nucleus. Cytoplasm. Note=The phosphorylated and active form accumulates selectively in the nucleus.
Interaction partners:
- Myeloid differentiation primary response protein MyD88
- Interferon regulatory factor 3
- TNF receptor-associated factor 6
- Interleukin-1 receptor-associated kinase 1
- Interleukin-1 receptor-associated kinase 4
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon
- TNF receptor-associated factor 3
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Serine/threonine-protein kinase TBK1
- Antiviral innate immune response receptor RIG-I
Sequence:
MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA
Protein: Protein FAM43B (Zgc:92105) (Q66I09)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MLPWKRSKFVLVENESKSKPKSLGAGLTYHSLLSTLLHSCPDLLPDCPFHWLGSVFHSKRQKVELNKEEPTYNVRYLGSAVTIVAKGEDCTQEAVAKIWTRSNYGEQSAKMKITVGPHGIRMGVDKSGKKKPSHLFSLNRITYCTADPFRPKILAWIYRHQVKNKAVVLRCHAVLLAKAEKARALALSLYQNTTSAFTEFKRLKRQSDFRHCQQQLLGEDIVPLMPLRRLLNGQCHYQPPAEKPGSATRLSSITEEEEDEDELGGAQSTNTSPEKDVGKIVNRLDEVSVTSWDEAQMTISTLV
Protein: 4-hydroxyproline 2-epimerase 2 (4Hyp 2-epimerase 2) (4HypE 2) (EC 5.1.1.8) (A6WXX7)
Organism: Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37) (Ochrobactrum anthropi)
Function: Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Can also catalyze the epimerization of trans-3-hydroxy-L-proline (t3LHyp) to cis-3-hydroxy-D-proline (c3DHyp), albeit with 170-fold lower efficiency. Displays no proline racemase activity.
Interaction partners:
- D-amino-acid dehydrogenase
- Pyrroline-5-carboxylate reductase
- Ferredoxin
Sequence:
MARHSFFCVDGHTCGNPVRLVAGGGPNLEGSTMMEKRAHFLREYDWIRTGLMFEPRGHDMMSGSILYPPTRPDCDVAVLFIETSGCLPMCGHGTIGTVTMAIEQGLVTPKTPGKLNLDTPAGLVAIEYEQNGQYVERVRLTNVPAFLYAEGLEVECPDLGNLKVDVAYGGNFYAIVEPQENYTDMEDYSALQLIAWSPILRERLNEKYKFQHPLLPDINRLSHILWTGKPKHPEAHARNAVFYGDKAIDRSPCGTGTSARMAQLAAKGKLKPGDEFVHESIIGSLFHGRVERATEVVGQDRTLPAIIPSIAGWARMTGYNTIFIDDRDPFAHGFTVA
Protein: Eukaryotic translation initiation factor 4E, putative (Q386T3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Eukaryotic translation initiation factor 4E, putative
- Probable eukaryotic initiation factor 4A
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- 14-3-3-like protein, putative
Sequence:
MMAESSAKEMEANQVSAAGDQTAKADDRYVIIDRGVKRHLLNRPWTLWYDSVSTYDCKQWELSLIEVMTVRTVEDFFAMLHYCKPPHVLRVSAQYHFFREGVKPMWEDPNNKAGGKLWVSLDDKTMTDKSGAAGGGKTRKDNGADADKKPELDTVWENVLIALVGEYLDYGVEGEHIMGVVLTKRKYCNRIALWLKDASDSDAVAAIEKQLVKEAGLLPATKPIFTAHGASKA
Protein: Receptor protein-tyrosine kinase (EC 2.7.10.1) (Q7SZF7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}. Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAGPTEIGLFFTLLLSGSFCATPEKKVCQGANNKLTLLGTVEDHYQVLLRMYRNCTVVLENLEITHITEKYDLSFLKSIQEVGGYVLIAVNTVSKIPLENLRIIRGHSLYEDKFALAVLVNFNNSIEQGVKELPLTSLTEILKGGVKFCRNDYLCNVGTIEWADILNMKSLPTIVSHNISYGKNCGKCDPSCFNGSCWGTGPDKCQRMTKVICAEQCSGRCKGPRPIDCCNEHCAAGCTGPRPTDCLACKDFQDEGTCKDACPRLMLYDPNTHQLAPNPYGKYSFGATCIKTCPHNYVVTDHGACVRTCSPGTYEVDEGGVRKCKRCEGLCPKVCNGLGMGPLANVLSINATNIDSFENCTKISGNVAILSTTFRGDPHTNTSGLDPAKLSVLSTVKEITGYLMIQLWPESMQSLSAFENLEVIRGRTKTQGTYSFAVTKTAITHLGMRSLREISDGDVSIVKNKNLCYSSPEHWKRLFKSKQQSVKMIENMDAATCANQNSTCNEMCTADGCWGPGPTMCFGCEHYSRGKHCVASCNLLNGEPREYEVNKTCMECDPECLLMNETQTCNGPGPDKCTVCANYKDGPHCVHRCPQGVPGEKDTLIWKYADVTHVCQPCHENCTQGCTGPDLKDCKDFKSSGLPMIAAGVVGGLLAFVILALGVAVLLRRRHIRRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVHKGLWVPEGENVKIPVAIKVLREATSPKANKEIMDEAYVMASVEHPHVCRLLGICLTSTVQLITQLMPYGCLLDYVRENKDRIGSQHLLNWCVQIAKGMNYLEERHLVHRDLAARNVLVKTPQHVKITDFGLAKLLNADEKEYHADGGKVPIKWMALESIQHRTYTHQSDVWSYGVTVWELMTFGTKPYDGIPASEIAGVLEKGERLPQPPICTIDVYMIMVKCWMIDAESRPRFRELIAEFTKMARDPSRYLVIQGDDRMHLPSPSDSKFYRSLMSGELDEAVDADEYLVPNHSFFSSPSTSRTQLLHSVSLNSSFGNCNSRNGNGYPVRENSMVLRYIPDPTERFQEGDFQPAPGYNEYMNQNESSMINPVYQQPHGPPRTLLHSSPALDETEEEYLNCFKSPAPASVVEYLNTSHTQLLSTKPFFSMDNPDYQQDFCPLELKTHTNGHLPAAQNQEYMGLEVH
Protein: Protein modigliani (B7Z0L8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000269|PubMed:19181850, ECO:0000269|PubMed:19240120, ECO:0000269|PubMed:20679394, ECO:0000269|PubMed:26110638}. Chromosome {ECO:0000269|PubMed:19181850, ECO:0000269|PubMed:19240120, ECO:0000269|PubMed:20679394, ECO:0000269|PubMed:26110638}. Chromosome, telomere {ECO:0000269|PubMed:19181850, ECO:0000269|PubMed:19240120, ECO:0000269|PubMed:20679394, ECO:0000269|PubMed:26110638}. Note=Localizes to euchromatic telomeres of polytene chromosomes (PubMed:26110638). Telomere localization is not dependent on peo/pendolino (PubMed:26110638). localizes to specific interband regions on chromosomes (PubMed:19240120). Localization to telomeres is dependent on ver/verrocchio and telomere associated cav/HOAP (PubMed:19181850). {ECO:0000269|PubMed:19181850, ECO:0000269|PubMed:19240120, ECO:0000269|PubMed:26110638}.
Interaction partners:
- Telomere-binding protein cav
- Trimethylguanosine synthase
- Protein verrocchio
- Protein telomere ends associated
- Probable small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein F
- Probable small nuclear ribonucleoprotein G
- Probable small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein-associated protein B
- LP09875p
Sequence:
MSLVPEASTSRAPKYCYFFKTLLVEELELETSYHNLHYGQCALIGRLAFKANQYRLENVRVKCLPKKYSLGEGTVSLLILGLTHDKVVENRVSTGRYCIVRGEVVLHNVQHPKGAKLTAGGVYDKINSLSNDPLAQKQYLSALLATYRPAIDLWYIQVIDRAEDLLTRRLEMRSLIEK
Protein: F-box/kelch-repeat protein At1g80440 (Q9M8L2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F-box/kelch-repeat protein At4g39580
- At1g30860
- Lysine-specific demethylase JMJ21
- Defensin-like protein 194
- F28K20.8 protein
- At1g31240
- Putative receptor-like protein kinase At2g30940
- SKP1-like protein 20
- F-box/kelch-repeat protein At1g23390
- Receptor-like protein 34
Sequence:
MELIPNLPDDVARECLLRSSYQQFPVIASVCRAWNREVSLSQFLHQRKASRHSQELLILSQARVDPAGSGKIIATPEYRISVLESGSGLWTELPPIPGQTKGLPLFCRLVSVGSDLIVLGGLDPITWQAHDSVFVFSFLTSKWRVGATMPGVRRSFFGCASDSDRTVLVAGGHNEEKCALTSAMVYDVSEDKWTFLPDMARERDECKAVFHAGRFHVIGGYATEEQGQFSKTAESFDVSTWEWGPLTEDFLDDTGDTVSPPTCVAGGDLYACWGGDVMMFLNDKWQKVGQIPADVYNVTYVAVRPGMLIVIGNGKALAGYGEATVGYICDLSSSRWVKLETHGGHVQAGCFLEV
Protein: Kunitz-type serine protease inhibitor BmKTT-1 (Delta-KTx 2.4) (P0DJ49)
Organism: Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)
Function: Dual-function toxin that completely inhibits trypsin activity at a molar ratio of 1:1 (dissociation constant of 136 nM) and that inhibits mKv1.3/KCNA3 potassium channel currents with an IC(50) of 129.7 nM.
Subcellular location: Secreted {ECO:0000305|PubMed:22354971}.
Interaction partners:
Sequence:
QKDCSLPVDTGRGKGWFLRYYYNKNSKTCESFIYGGVGGNKNNFLNIENCCKICKAKNC
Protein: Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2) (E9Q612)
Organism: Mus musculus (Mouse)
Function: Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function.
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MGHLPRGTLGGRRLLPLLGLFVLLKIVTTFHVAVQDDNNIVVSLEASDIVSPASVYVVRVAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFNHWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPPQDSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPDPNSTDYESTSQPFWWDSASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS
Protein: Fucose-1-phosphate guanylyltransferase (EC 2.7.7.30) (GDP-L-fucose diphosphorylase) (GDP-L-fucose pyrophosphorylase) (O14772)
Organism: Homo sapiens (Human)
Function: Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.
Subcellular location: Cytoplasm.
Interaction partners:
- GDP-L-fucose synthase
- L-fucose kinase
- Serine/threonine-protein kinase TNNI3K
- Leucine-rich repeat and IQ domain-containing protein 3
- GDP-mannose 4,6 dehydratase
Sequence:
MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADEKQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSFTILLIHSGGYSQRLPNASALGKIFTALPLGNPIYQMLELKLAMYIDFPLNMNPGILVTCADDIELYSIGEFEFIRFDKPGFTALAHPSSLTIGTTHGVFVLDPFDDLKHRDLEYRSCHRFLHKPSIEKMYQFNAVCRPGNFCQQDFAGGDIADLKLDSDYVYTDSLFYMDHKSAKMLLAFYEKIGTLSCEIDAYGDFLQALGPGATVEYTRNTSNVIKEESELVEMRQRIFHLLKGTSLNVVVLNNSKFYHIGTTEEYLFYFTSDNSLKSELGLQSITFSIFPDIPECSGKTSCIIQSILDSRCSVAPGSVVEYSRLGPDVSVGENCIISGSYILTKAALPAHSFVCSLSLKMNRCLKYATMAFGVQDNLKKSVKTLSDIKLLQFFGVCFLSCLDVWNLKVTEELFSGNKTCLSLWTARIFPVCSSLSDSVITSLKMLNAVKNKSAFSLNSYKLLSIEEMLIYKDVEDMITYREQIFLEISLKSSLM
Protein: Ciliary microtubule associated protein 1B (Outer dense fiber protein 3-like protein 3) (Outer dense fiber protein 3B) (A8MYP8)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q920N1}.
Interaction partners:
Sequence:
MGSDAWVGLWRPHRPRGPIAAHYGGPGPKYKLPPNTGYALHDPSRPRAPAFTFGARFPTQQTTCGPGPGHLVPARMTVRGTDGAPAYSIYGRPRRSAPFLTPGPGRYFPERAGNATYPSAPRHTIAPRNWGVQAEQQSPGPAAYTVPSLLGPRVIGKVSAPTCSIYGRRAAGSFFEDLSKTPGPCAYQVVSPGVYKSRAPQFTILARTSLPQDNTRKPGPAAYNVDQHRKPRGWSFGIRHSDYLAPLVTDADN
Protein: Lysyl oxidase-like (EC 1.4.3.-, EC 1.4.3.13) (Q9V9X5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Mirror, isoform C
- Lysyl oxidase-like 2
Sequence:
MASFRFQLLQLLVVLSQGWANLNVQNNYRNMMVRLATNKAALAGIQVLREGRVEVSFDFGASWGTICSTSWSMREANVVCRQLGLGYASKASQGTEHGDSRKYPWGMVGTLCRGTERRLADCIRESHYPNLCNARNHNVSIAACVSHSADLEIGLVDIERTARLEAVPMSRLTCAMEEHCVSADAYEIRRTNPHAARILLRFSVKASNVGTADVSPYANYKEWVWHQCHRHYHSMNVFATFDVYDLNYRKVAQGHKASFCLMDSECRPGVRQKYTCGNTTQGISVGCADTYTDVLDCQWVDVTRVPINRRYILRVALNPEYKLGEISFENNGAECLLDYTGVRQTTRIFNCRRKPLWFKI
Protein: A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-) (P59511)
Organism: Mus musculus (Mouse)
Function: May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease-independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
Sequence:
MRVAKWLTGLLCPISLLLTGSWEVRFHPRQEALVKTLASYEVVTPTRVNEFGDVFPQNRHFSRKKRSSGVPEPPPFRTHYRISAYGQLFQLNLSADAAFLAAGYTEVHLGTPVPGPGGRSTESPDLRHCFYRGQVNAREDHTAVFSLCGGLMGTFKANDGEYFLEPVLRADGSAHDDDHNKPHLIYRQELKRNSFARSHKPCEVSENQMEKTALPSQSSRNTTGDVDIEEEAVFRLEGERSQLHSRNKRFLSYPRYVEVMVTADAKMVHHHGQNLQHYVLTLMSIVAAIYKDSSIGNLINIVIVKLVVIHSEQEGPVISFNAATTLRNFCLWQQSQNVPDDAHPSHHDTAVLITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVPHDDSFKCKEAGIKHQYHVMAPTLNYHTSPWTWSACSQKHITEFLDTGHGECLLDKPNGRTYDLSPQLPGSVYDGNRQCELMFGPGSQVCPYLKHCRRLWCTSAEGVHKGCRTQHMPLADGTSCGPGMHCHRGLCVTRDMETRPVDGEWGPWGPYSSCSRTCGGGIKSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFDGKHFDINGLPPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETNDICVQGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFNSAHYGYNVVVKIPAGATNIEILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERINSTDRLEAELVLQVLCVGNLYNPDVRYSFNIPIEERSNLFSWDPYGPWQDCTKMCQGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRWHIIGKSDCSSQCGQGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRELPRVVLENCNEFPCPSWATSEWSECPVTCGKGMKQRQVWCQLSEDPMRDGFCNASTKPESLRPCELRACASWHVGPWGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIPEVGATSLPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDEVADESNCAHLPRPAAVSLCFSPCGEWQAGDWSPCSASCGHGKTTRRVLCVNYHQLVDESYCDPEGRPVTEQECSLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVCQDEDGRSATSCDGSSKPPESRHCGSGPCPHWNYGDWGECTQTCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSCSASCGKGVKYREVLCIDQFQRKLEEKYCSHLHKPRTHKACRSGRCPSWKANKWKECSVTCGSGVQQREVYCRLRGTGRVSEDMCDPSTRPQGQRQCWRQDCMRYQWTTGDWLDCSTSCKKKETYRLVKCVNEQNVQANESLCDPLTKPLSIKKCRNPHCKYSVVTGDSSQCAGNCGFTSPQKITYCTKIQSSKKHTFHQLRPVVYGECPVIPSPQAYKCDLRSCLHVATWKVGKWSKCSVTCGIGIMERRVACRTENGWPSDLCLKRLKPDAQKKCYANDCKLLTTCKELQVTNNVTKDGDYDLNVRGRILKIHCSGMQLENPREYLPLVKSEDNFSEIYGLRLQNPYECPFNGSRRPDCACENDYLPAGYTVFSKVRVDLESMQIKTADLLFSQTLSGKAVPFATAGDCYSAARCPQGQFSINLAGTGMKISNTAKWLAQGRYASVIIHRSQDGTKVYGRCGGFCGKCIPHMATGLSIQVL
Protein: Transcription factor E2-alpha (Transcription factor 3) (Q90491)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MATVGTDMELNDLLDFSIMFPHPMSNGKSRGPNIPSSQFGLDDRNDSGSWGSEANSPSFGARLYGDGHHYPEHDNMYNLEIDGKSERGYPVTQLLPGEINIAASDALSPPGMKGSSQFYSPHRRRPAESSIDPLPKKRKVPHGLPTSISAYPGSTGDDYNQDSAGYPGSKPGNLYPGFFNVQEGLPDHWGQSGYPPVMSNFINPQKPQPLPVSPQNYPLHGSEVNLPSSFHSVPAGYGVPNHTPPISSSEGIMGNRGANAGSSGAEIGKALASIYPSDNNGSNFSSTPSTPVGSPSNVAASASQWPKGSSQPAPSPGFEAGLAQSKLDDRLGEALHVLRNHHAVGTDMQSLLSAAISGHSAGAAALGSLRQAFGLANRLPGLMSNHSEDAAGLPQSSALLQGHHTSHQPPPSSQSDTFTSLSLARSSHASSSDIKREDKDDDENLSIADKSEDEKKDGKSRTRTSQDEDEDEDDEDLPVEVKAERERERRMANNARERLRVRDINEAFKELGRMCQLHLSNEKPQTKLLILHQAVNVILNLEQQVRERNLNPKAACLKRREEEKVTGEAQMLSGLGGDGHAHM
Protein: Vacuolar basic amino acid transporter 3 (P25594)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transporter required for vacuolar uptake of histidine and lysine.
Subcellular location: Vacuole membrane; Multi-pass membrane protein.
Interaction partners:
- Vacuolar basic amino acid transporter 1
- Uncharacterized transporter YMR279C
- Glutathione exchanger 1
Sequence:
MNMLIVGRVVASVGGSGLQTLCFVIGCTMVGERSRPLVISILSCAFAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAENKGILQQIKDAIGTISSFTFSKFRHQVNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTFGGNKYSWNSGQVIAYLVLGVLLFIFSLVYDFFLFDKFNPEPDNISYRPLLLRRLVAKPAIIIINMVTFLLCTGYNGQMIYSVQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGVITKKLGLVKPLLIFGGVLGVIGAGLMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLMSAQLQITKDRPEAAMDFIEVTAFNTFMKSLGTTLGGVLSTTVFSASFHNKVSRAHLEPYEGKTVDDMILYRLQNYDGSHSTIGNILSDSIKNVFWMDLGFYALGFLFCSFSSNKKLIIPKKDETPEDNLEDK
Protein: Magnesium transporter MRS2-7 (Magnesium Transporter 7) (AtMGT7) (Q304A0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Low-affinity magnesium transporter that mediates the influx of magnesium.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19966073}; Multi-pass membrane protein {ECO:0000269|PubMed:19966073}.
Interaction partners:
- Putative non-specific lipid-transfer protein 14
- Magnesium/proton exchanger
- Suppressor of mec-8 and unc-52 protein homolog 2
- Suppressor of mec-8 and unc-52 protein homolog 1
Sequence:
MSPDGELVPVDSSAVVTAKRKTSQLSRSWISIDATGQKTVLDVDKHVIMHRVQIHARDLRILDPNLFYPSAILGRERAIVLNLEHIKAIITAEEVLIRDSSDENVIPVLEEFQRRLPVGNEAHGVHGDGDLGEEDESPFEFRALEVALEAICSFLAARTTELEKFAYPALDELTLKISSRNLERVRKLKSAMTRLTARVQKVRDELEQLLDDDGDMADLYLTRKLVGASSSVSVSDEPIWYPTSPTIGSMISRASRVSLVTVRGDDETDVEELEMLLEAYFMQIDSTLNKLTELREYIDDTEDYINIQLDNHRNQLIQLELMLSAGTVCVSVYSMIAGIFGMNIPNTWNHDHGYIFKWVVSLTGTFCIVLFVIILSYARFRGLIGS
Protein: YopD protein (A0A0N9NCT8)
Organism: Yersinia pseudotuberculosis
Interaction partners:
Sequence:
MTINIKTDSPIITTGSQLDAITTETVKQSGEIKKTEDTRHEAQAIKSSEASLSRSQVPELIKPSQGINVALLSKSQGDLNGTLSILLLLLELARKAREMGLQQRDIENKATITAQKEQVAEMVSGAKLMIAMAVVSGIMAATSTVASAFSIAKEVKIVKQEQILNSNIAGREQLIDTKMQQMGNIGDKAVSREDIGRIWKPEQVADQNKLALLDKEFRMTDSKANAFNAATQPLGQMANSAIQVHQGYSQAEVKEKEVNASIAANEKQKAEEAMNYNDNFMKDVLRLIEQYVSSHTHAMKAAFGVV
Protein: Phenoloxidase 3 (EC 1.14.18.1) (Diphenol oxidase A3) (Diphenoloxidase subunit A3) (Prophenoloxidase 59) (Tyrosinase A3) (Q9W1V6)
Organism: Drosophila melanogaster (Fruit fly)
Function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone (By similarity).
Subcellular location: Secreted {ECO:0000250}. Note=Expression not detected in larval hemolymph. {ECO:0000269|PubMed:19141111}.
Interaction partners:
- Aspartate aminotransferase
- Aspartate aminotransferase, cytoplasmic
- Aromatic-L-amino-acid decarboxylase
- Tyrosine aminotransferase
- tyrosinase
- MIP05841p)
- 3,4-dihydroxyphenylacetaldehyde synthase
- Tyrosine 3-monooxygenase
- Protein henna
Sequence:
MADKKNLLLLFDHPTEPVFMDKGGNGTVFDVPDSYVTDRYNQMCKKVQRRVSSASEKNVQVKEIAIPDLSCSMRLGRSEQFSIFLKSHRKMASHLIEIFTKMQTVDELQSVAVYARDRVNPVLFNYALSVALLHRPDTKDLELPAFAQTFPDRFIDSKMLRSMREESFVVERSAARLPVVSSVKYTASDLDVEHRLWYFREDLGVNLHHWHWHLVYPIEAPDRSIVDKDRRGELFYYMHQQIIARYNAERLSNHMARVQPFNNLDEPIAEGYFPKMDSLVASRAYPPRFDNTRLSDVDRPNNQLRVGIDDMKRWRERIYEAIHQGYVLDTNNEKIVLDDAKGIDILGNIIEASDLTPNSTLYGDFHNMGHILIAYSHDPTNKHLEYAGVMGDASTAMRDPIFYKWHAFIDNMFQEHKRLLSPYEKQELSFPDVRVESIQVESQGQVNRLTTFWQESDVDMSRGLDFVPRGHVLARFTHLQHHEFSYTIKVENSSEATRYGYVRIFLAPKLDDRNAPMLLEQQRLMMVELDKFVVTMPPGSHTITRNSTESSVTIPFERTFRNLDKLEELQNFLCGCGWPQHMLIPKGRPEGLRFELFVMVSNYEEDKVDQTVADCGCSIAASYCGLRDRLYPDRKSMGFPFDRKPRRGSEILENFLTPNMCAVEVIITHEDRTEKLREVPARS
Protein: Heat shock protein 70 (Q8IB24)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- non-specific serine/threonine protein kinase
- Endoplasmic reticulum chaperone GRP170
- DNA-binding chaperone, putative
- HSP40, subfamily A
- Heat shock protein 90
- Heat shock 70 kDa protein
- DnaJ protein, putative
- GrpE protein homolog
- Hsp70 nucleotide exchange factor FES1
- Heat shock protein 90, putative
Sequence:
MASAKGSKPNLPESNIAIGIDLGTTYSCVGVWRNENVDIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVARNPENTVFDAKRLIGRKFTESSVQSDMKHWPFTVKSGVDEKPMIEVTYQGEKKLFHPEEISSMVLQKMKENAEAFLGKSIKNAVITVPAYFNDSQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLHKKGKGEKNILIFDLGGGTFDVSLLTIEDGIFEVKATAGDTHLGGEDFDNRLVNFCVEDFKRKNRGKDLSKNSRALRRLRTQCERAKRTLSSSTQATIEIDSLFEGIDYSVTVSRARFEELCIDYFRDTLIPVEKVLKDAMMDKKSVHEVVLVGGSTRIPKIQTLIKEFFNGKEACRSINPDEAVAYGAAVQAAILSGDQSNAVQDLLLLDVCSLSLGLETAGGVMTKLIERNTTIPAKKSQIFTTYADNQPGVLIQVYEGERALTKDNNLLGKFHLDGIPPAPRKVPQIEVTFDIDANGILNVTAVEKSTGKQNHITITNDKGRLSQDEIDRMVNDAEKYKAEDEENRKRIEARNSLENYCYGVKSSLEDQKIKEKLQPAEIETCMKTITTILEWLEKNQLAGKDEYEAKQKEAESVCAPIMSKIYQDAAGAAGGMPGGMPGGMPGGMPGGMNFPGGMPGAGMPGNAPAGSGPTVEEVD