Protein: Dynein heavy chain, cytosolic, putative (Q57YC6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Tubulin beta chain
- Tubulin alpha chain
- Cytoplasmic dynein 2 heavy chain 1
- Cytoplasmic dynein 2 heavy chain 1
- Ras-related protein Rab-7b
- Cytoplasmic dynein 2 light intermediate chain 1
- Uncharacterized protein
- Dynein light chain
- Dynein light chain
- Dynein light chain
Sequence:
MMRQEKDKQLCLTADELLASDVVDCISSMMRSATKPQVREALQGVEHEKNGTALHLVVCEYTPTQNLNNEEAATTTCVVAAEDLTTVFFRLMATVSRGVTSPKYMGTGPMTEGSKNVDGGSSMETEGAAALPRVTRCVFITSASGGNSAEDIRNAPSSPRPAPLTLSQLNVHAMEMDQPLGDLQSLLQRVYEPVLRQRREDALRYNLQEFVNSMQCRYHFLTRVNLMQFVHPKLLTVCSVNPTADLHELVGLLHEEGDDVDLDDVFAIWSPCRNLLNVAFEADTADDGNAARPQVINLSEVVGGAPHHGSCIGDNTSRNHGNNNNGGVLEEVSYWQEVRQWINHIRRQLRSREWRLAHYLLRHRVPTSYEREYELHSKLAHSYEQHAKGVLQLLPHINDVNDITTFLVNALRIIEAAARPGAYPRKRCTHFVNCVVHNIMEQFVALADGLDVLHIQPAEKQLQKIGEMMKAIVELQRCLVDGVLSARIDQRDVEGTTVTETRNSSVAGQWCTEVKNLSGFGRCSLLLERMKQLKDFLNEHFHYYRTLAQTFAEGGGSGSTTTSFCRHLAEAYSRFTADVVERGCLWDVSPTGAGKYQRIRDSYSSRVSRIDDRLALHVGISLSNEQERDTYNVTTSTVKANTSTEAKTSDPRRPARGRVDAPTAGGSPLYRAYSCFCVFRREKVLAVLASFRTALREQIDREINDICEEYFGKESCPHIVRATVARLGVTEDVGRMLWERSLQRQLETHMERREEISEHGWRQLLLLRTLEHRWCLNESLARFFGARLQDLVVEGFAAGSEVHGTAYALAFLSLVHSKNELRWSRDPHIQSARQYLDENSPQSLEKARLRLVLLRKGSSWGSKQSEPWDVLNFRDSIAQKLNEHVERWCNIVQSKFLHVDMVEETMAMKGPFLRLSYVERGVGTAGGNSDKNNNFHRNNEGNIDGVSRGEQVLVPNIPQEMYAFLRDFYTLESVQLQEKHKQLFGNIRCFFLKNEARFRIANSFRDLTRVFEEAVGDEEELMAHLITDEYAQVYGCLVDGAKLTWLEEDKLLEFIQRLSCRVYNFCSAASSVRTAVDDVERILQQLHSQTFAAQSIVEKVEKLCGIVKQLGSEGSSREWYVQRIQPRLDAALLLQLQAHLHRWTVEFLSMGRDPRFLDPASCTEEYKLRPLRIRMRVLFKGITLATPEAACRYHWLNILNNSFAWLHAIPALHSSFRRSNHQHPTATPLFGGGSVVEVTAETVYGRLVDCLSSEVLAEPMTAIDKSIQEAFDVEKQWRRGQQLLNLEVGVLQQKLGDDLVKWEEALRHIREFADTLMNHTQPSTLLGGILIVASDAQKELGRKLDNMTQYINSRYREVVSKHLELCHRRITEERTDVEKCDVINSIDDACMFICELPTIYTKLEETGRRIAPLVAAEEYLKNQGLSLPDSGVCVKKVKEEHQAYKDLIARKVKAVELRRPFLRENAKQKGKGLQDDVAELEKSLAELDKQIQLRERQDKQHLEELADSMQERFYDIQKQILVLEKQHDRLTLLCKVLGIQPVDEVRLQSVASRTENLRWVFGHLLEVCRKLNRLSQTPFSEVDPQRLHEDIISLQAEVQEFPPGVRGHPAHNELVQLIEERLAARWIIHELSSRAMMPVVRAERHWSLLRSKLGTQWKLEELTVGDIWRSDPMTRAKIYYEVLDVARGEHRLETKLEQITAFWNNFEFNTTIYKKKHVLIRGWDAVFAQLSDDIDTLQGFHLSPFYSASHIAASVTEWESRLNLLLKVLEVLMGVQRRWVHLDGLFSSNEDIYQQLSSEGMQFDRVTWELWNLMPYRSSPFGSTETAADLENVVVRTQDFLEEKRLLSSLERVDGQLTRVQRALNRYLDRQRRLFPRFFYVGDDDLLETLGNSNNATLIAKHLPKMFTALARLIVKDMGANGQGSAGSAAADLHIVGFACEEGEEVATNRSIRLEGRALHLTLNEVEIVMTQTLRQLTVSAAASLADAGCVTTEWIEAFPLQVVCLAFQVWWAQLQEQALATWKAQQKREPSLAVSRMVSLLDQLALEVTAVGVTPSVRRASEELITLAVYQRDVSRLIELKNVTAAEDFEWMRILRLYVVAPDTYSKKGDAATDVGRPRKSGVVLANEVDYPEVHCRMADASLIHGFEYIGWYRRLVQTPLTDRCYLAMTQALHTRLGGSPVGPAGTGKTETVKSLGAQLGRHVVVFNCTDTFDFSAIGRILMGLCQVGAWGCFDEFNRLEECVLSAVAQQIRSIQEALRGDLHSVNLSRQQVPLKTNVALFITMNPDFADRSQLPGNLKQLFRTVTMVAPDREAIAEVMLFAQGFRTAESLSRKVVPLFDLCREQLSRQSHYDFGLRALKSVLVIAGEAKHADCKRNAVHVPETASSATAVEDDSNVNSRECELMLGSLINNIVPRLISEDVILFYPLLRDFFPGRPVPDVFESLLRSTIEEVCQDTHYTPTPAWVEKIYQLYRTRKTRHGLMLVGPSGTGKTSCWKTLLRVMARLSTQEGHNDFDEGDLASPSRRSRGRPLEAHAYVIDPKAMTKAELFGVFEATTREWKDGIFTDILRRIVNNSLDTNSTQQQHWIIFDGDVDPLWVENLNSLLDDSKIYTLPNGERLSLPPSVRIVFEVQDLRYATPATVSRCGMVWFSHGTVPVSCLLNRHLTTFLRAPMIDKRGGKRIVEVCDDHEEMQSRLCGGHFTLHRAAASSGTTTLASTQRELTTSDGDVRTSRENNKAHDSLTEDALNRSARNSENVPESPPPRTPHSFVSAERDILELQVFMVGVWTTAFAKGGLLERAFEIIHTERYRGQGIMEHNDLQILRSVQSLLLDGIWSMWQVREKWGALPTERVVRSYAEKLLNYAVFWGFGAALNNELRRQLLDDIGFQLLGQPRDLTLMDVEPDPVHGTWRTTRERVQPVDVDPEDVGFSDVIIPTVDACRNRTLLEAWITGGDAVILCGPPGSGKTILVTSLLRDSFTHESVFLNFSSGTRPENIIRALEQYCSVHNHAVHGPIMTPTSGKRLLLFCDEVNLPALDQYGTQPVVQFLRQLVERKGYYRSRDNVWVTVEGVQVIGACNPPTDKGRVSLSHRFLRWAPVLFVDFPTEESLHVIYSSYCRAMLSFSSRLQRYHPKCLAAAMVDVYTASQSRFNTWQQPHYVYSPRELTRWIRALRGAILSWSDQQRCELTVEELVQLAIHEGLRIFQDRLVQNEEREWAHRKVVECFARHFTDVTSSPAQPPLLFSSIVNGVYMKQTKSELVQYVEEKVRTFCEGEGDTELVVLDTMVDHVVRIDRVLRQPSGHMVLVGASGVGKTIITRLVAWMNGMSVFRIDVNRGYQLADYERDLREVLRRAGCGLERICFIFDDSNAMETGFLEYINALLPSGEIPGLFDGDKWAKLMDDIRASVEEQQSLKATSGTTQHLPRVLQHHQHEREGNELHNSARTSLFDRSSTMNRRDFGAPMTGGGYDFDRHPLLLNETAGPMLTSDYIDITSEQVLYRWFVNNVRRNLHVVFVTDPSTKEFADRVVTSPALFNRCTINWLGEWDRTTRAQLAQKLTQNMDVMFSCRESFSGSEDTSRKALTEALSAIHEATEEVNSTARQRNANSGTFITPRHFSDLLQQLKLLYEEKKGRSMEQLTHLRSGLAKLATTSEEVGQQQTQLREHEVLLDERSAKAQAMLERIVSETERTKQEKQEAEQLRQQLKEEEDLILADRARVEQQLSEAAPALREAEEGLNSIKQEYLREMRAYTTPPTMVKRVLETVLVVMGERRAGEWDVIKHYVRRDDFIASVKAFQARDVTEEAVQTVRGMLQEDGFTYEAAMRASKAAGPLLQWVTAQINYAIVYAAVQPLRSRIDQITITQGAKQAQLERTETEISTLEMSLQQLKEDYQSMAEEIATCKSTMGVIASRCDRATKLLQQLLEERDRWGAESLGFDSEVSVLLGNCILAAASLTYFGYFDEYTRQSLLLPVWVQQLKNFKIRCTEEHSSGFVDYLVTPSQRLEWEQQGLPKDNLCAENAMILHRSRRYPLLIDPSGVATAFLQKKHKDGTMRTTSFTKSDYLKQLDMAIRFGYALIIEDAEFMDPIIGPLLKNEMRRVGGRTMTRLGGREVETTSSFSLILITRDSHYQPPPGIAGRVCLVNFAVTLSSLESQCRHRLLLHERADVDEQRARVLKVREEYSVRVRVLEQELLKLIAGSEGSILENNTLTVALERLKGETKALKEGIVESDELMRSITAVEEHYKPLATAVSKVYFVLRCFSQLHGLYQYSVKFIFRVLNDALDQLPPPSNSNGAQQEEAPAEKKEEDAARLQVLTRHVFYLLYHRARRGMFAQDHLVLATALGKARSGIADPIGQQLTIEEWNLFESALGGPVASTGVSIPAESIKGADRLDQLPKILSGCRVCSPSSAAVLAELLKLPLFEQVRVSLNNPEHGEAWRAYFAAVEPYAETIPPFSRKVKNFSADDANCSSVGGSHAVGPTRRAFITALLLLHTRRDAFVPAASEFLRLFFDGADVAVGDGRGNCGESGYRAIAGHDGAKGGMGDFDSFFSAEVLDLVAIQKELTNTTPLILVANAGSDPTVSLEAVASAMNVQLHTAVMGSADSTEAAERFLTTATVDGAWVLLKNIHIDRAFADVVVRHLHRVFAGDQVHEGFRLILSMEAKAQHVVGNLGERGCGGDVINARSPLDLPVSLVESSIVVVYEPPPGMKASLLQTIGSLRAPTQQAPYSADMVRIYLTAAWFHAVVMERLLYVPLGWSTRYEINDTEFWHTLQAVNRWVMTTESTSGGNTVGDIEGNQVCSANREHFPWLALQTIIGTALYGGKLSNDFDQFLLNSFCTQLFSPIIFEDDKFFALLEGLCVNQKLRLPSMDTLNDVLAWVKSLPDPQPLRWARLPASASRLMLEKQAVAMLERLAILRFVGEKEHSGRSIVDGCAAYSEESTIPRCLTEMQWAQKVRLFCSSWRSSLERLVPAGQVVSAQSAETPSGGRSSGAERCKEEPVSVMVDREYAFAMERLHEVLDDLQVVENICCGTGKPTADQRALIDWLLKDQIPPMWARSYSSHTAVAEQWMIDFARRVSHALYLRGAIQRESGGAVCLNLGLLFWPEAFVTTTKQQTARRQSQPLEQLQIQLDLMPEEDVRARAAKVVKEDDVWHIVGLTLFSASLKKCDTASGGAGYTCVLLPDSSTAPSTPVGAVMRWRPVVLSRTTTAPDAGCCMAPAAKSSVLTRLASRDKNSNCLIVPLYASDLRRALLQVVELRVDIKNTPMHAWYERGTCLVAWSMEAY