wanglab/gogpt-training-data huggingface dataset:
Protein: RE52596p2 (Q9VMV7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Actin-related protein 6
- RuvB-like helicase 2
- RuvB-like helicase 1
- DNA methyltransferase 1-associated protein 1
- Uncharacterized protein, isoform B
- Vacuolar protein sorting-associated protein 72 homolog
- General transcription and DNA repair factor IIH subunit TFB5
- Histone H2A.v
- YEATS domain-containing protein 4
- Brahma associated protein 55kD
Sequence:
MTGRESNRIKDAEKKRVLDSTARQRRARKALEALEQDNYHDDPHADLVMSKKLPKFQDSLKTGKEKKGKRKGAEYFLVKYRKNFQQLLEEDKDKQPNYESAAAPAPQKPLRHFCAVCGNFSLYSCTACGTRYCCVRCLQTHQDTRCLKWTA
Protein: Tumor protein p53 binding protein 1 (C9JXV0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSGISNYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSS
Protein: Baculoviral IAP repeat-containing 5a (Baculoviral IAP repeat-containing protein 5a) (Survivin 1) (Q90WU9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDLASDDQTKMYFYENRLQTFVGWPFEEGCVCTPENMAKAGFIHTPSENSPDIAQCFFCLKELEGWEPEDDPEKEHKAHSPSCDFILLKKTVDSLTVEEFLKLQKERQKFIIKKSCGHAIDKFEDAVKLKRNQIIQTAMGEE
Protein: Alphabet, isoform B (EC 3.1.3.16) (Q8IMK7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}.
Interaction partners:
Sequence:
MGGFLDKPKTAKHNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDHVKGIRTGFLRIDEVMRELPEFTRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMIKRVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVTSNLVSIANQVVDTCLHKGSRDNMSIIIIAFPGAPKPTEEAIEAEHRLEKQIEKITRDEIESSKITDYVDLLKCLQNRDDIEGLPPGGGLQSKYHVIERTFKQEFPDRPCELYAYDDI
Protein: Yeast-form wall Protein 1 (GPI-anchored protein 24) (Thiol-extractable peptide 1) (flocculation protein 1) (Q59Y31)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization.
Subcellular location: Secreted. Secreted, cell wall. Membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. Note=In yeast cultures, is linked covalently to glucans of the wall matrix, but, as cultures approach stationary phase, accumulates in the medium and is extractable from cells with disulfide-reducing agents. Removed from the cell wall by proteolytic cleavage by SAP9 and SAP10.
Interaction partners:
- Agglutinin-like protein 3
- Cell wall protein RHD3
Sequence:
MKVSTIFAAASALFAATTTLAQDVACLVDNQQVAVVDLDTGVCPFTIPASLAAFFTFVSLEEYNVQFYYTIVNNVRYNTDIRNAGKVINVPARNLYGAGAVPFFQVHLEKQLEANSTAAIRRRLMGETPIVKRDQIDDFIASIENTEGTALEGSTLEVVDYVPGSSSASPSGSASPSGSESGSGSDSATIRSTTVVSSSSCESSGDSAATATGANGESTVTEQNTVVVTITSCHNDACHATTVPATASIGVTTVHGTETIFTTYCPLSSYETVESTKVITITSCSENKCQETTVEATPSTATTVSEGVVTEYVTYCPVSSVETVASTKVITVVACDEHKCHETTAVATPTEVTTVVEGSTTHYVTYKPTGSGPTQGETYATNAITSEGTVYVPKTTAVTTHGSTFETVAYITVTKATPTKGGEQHQPGSPAGAATSAPGAPAPGASGAHASTANKVTVEAQATPGTLTPENTVAGGVNGEQVAVSAKTTISQTTVAKASGSGKAAISTFEGAAAASAGASVLALALIPLAYFI
Protein: Large ribosomal subunit protein uL2cz/uL2cy (50S ribosomal protein L2, chloroplastic) (P0C497)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL5c
- 60S ribosomal protein L29
- Small ribosomal subunit protein uS14c
- Os06g0683200 protein
- Os08g0116500 protein
- Large ribosomal subunit protein bL27c
- Os01g0220300 protein
- Large ribosomal subunit protein uL16c
- Large ribosomal subunit protein bL33c
- Os04g0501000 protein
Sequence:
MAKHLYKTPIPSTRKGTIDRQVKSNPRNNLIHGRHRCGKGRNSRGIITARHRGGGHKRLYRKIDFRRNQKDISGRIVTIEYDPNRNAYICLIHYGDGEKGYILHPRGAIIGDTIVSGTKVPISMGNALPLTDMPLGTAIHNIEITRGRGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLVSQNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGKAPIGRKKPTTPWGYPALGRRTRKRKKYSDSFILRRRK
Protein: ORF 29b (P88919)
Organism: Human herpesvirus 8 type M
Interaction partners:
Sequence:
MLQKDAKLIFISSVNSSDRSTSFLLNLRNAQEKMLNVVSYVCADHREDFHLQDALVSCPCYRLHIPTYITIDESIKTTTNLFMEGAFDTELMGEGAASSNATLYRVVGDAALTQFDMCRVDTTAQQVQKCLGKQLFVYIDPAYTNNTEASGTGVGAVVTSTQTPTRSLILGMEHFFLRDLTGAAAYEIASCACTMIKAIAVLHPTIERVNAAVEGNSSQDSGVAIATVLNEICPLPIHFLHYTDKSSALQWPIYMLGGEKSSAFETFIYALNSGTLSASQTVVSNTIKISFDPVTYLVEQVRAIKCVPLRDGGQSYSAKQKHMSDDLLVAVVMAHFMATDDRHMYKPISPQ
Protein: DUF7159 domain-containing protein (O07745)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable membrane protein
- Indole-3-glycerol phosphate synthase
- Secreted protein
Sequence:
MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRNAQAIHTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWNAEASAQAALLVESLTGAGFDNVVPVRRLRAIETLAQAIAPVIGYEQIAVCVLEHESATVVMVDTHDGKTQIAVKHVCRGLSGLTSWLTGMFGRDAWRPAGVVVVGSDSEVSEFSWQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVADSVSQPTVAPRRSRHYAGAAAALAAAAVTFVASLSLAVGIQLAPHNDTGTAKHGAHKPTPRIAKAVAPAVPPPPTVTPPVPARAPRPAAQHEPPARVTSGEALTEPNPPEEQPNASAPQQDRNDSQPITRVLEHIPGAYGDSAPPAE
Protein: Threonine synthase (TS) (EC 4.2.3.1) (Q42598)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
Interaction partners:
- Homoserine kinase
- Homoserine dehydrogenase
- Threonine dehydratase, mitochondrial
- Putative phosphoserine aminotransferase
- Probable low-specificity L-threonine aldolase
- Aspartokinase
- Probable phosphoserine phosphatase
- Serine racemase
- Probable acetolactate synthase small subunit
- Aspartate-semialdehyde dehydrogenase
Sequence:
MSSQVSYLSTRGGSSNFSFEEAVLKGLANDGGLFIPSEIPQLPSGWIEAWKDKSFPEIAFEVMSLYIPRSEISADELKKLVDRSYSTFRHPETTPLKSLKNGLNVLELFHGPTFAFKDVALQFLGNLFEFFLTRKNGNKPEDERDHLTVVGATSGDTGSAAIYGLRGKKDVSVFILFPNGRVSPIQEAQMTTVTDPNVHCITVNGVFDDCQDLVKQIFGDVEFNKKHHIGAVNSINWARILSQITYYLYSYLSVYKQGKADDVRFIVPTGNFGDILAGYYAKRMGLPTKQLVIATNENDILNRFFKTGRYEKADSTQVSPSGPISAKETYSPAMDILVSSNFERYLWYLALATEAPNHTPAEASEILSRWMNEFKRDGTVTVRPEVLEAARRDFVSERVSNDETIDAIKKIYESDHYIIDPHTAVGVETGLRCLEKTKDQDITYICLSTAHPAKFDKAVNLALSSYSDYNFNTQVLPIEFDGLLDEERTCIFSGKPNIDILKQIIEVTLSREKA
Protein: Serine/arginine-rich splicing factor 1 (ASF/SF2) (Pre-mRNA-splicing factor SRp30a) (Splicing factor, arginine/serine-rich 1) (Q6PDM2)
Organism: Mus musculus (Mouse)
Function: Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing (By similarity). Specifically regulates alternative splicing of cardiac isoforms of CAMK2D, LDB3/CYPHER and TNNT2/CTNT during heart remodeling at the juvenile to adult transition. The inappropriate accumulation of a neonatal and neuronal isoform of CAMKD2 in the adult heart results in aberrant calcium handling and defective excitation-contraction coupling in cardiomyocytes. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q07955}. Nucleus speckle {ECO:0000269|PubMed:28785060}. Note=In nuclear speckles. Shuttles between the nucleus and the cytoplasm. Nuclear import is mediated via interaction with TNPO3. {ECO:0000250|UniProtKB:Q07955}.
Interaction partners:
- Serine/arginine-rich splicing factor 2
- Serine/arginine-rich splicing factor 10
- SRSF protein kinase 1
- Serine/arginine-rich splicing factor 7
- Splicing factor U2AF 65 kDa subunit
- U1 small nuclear ribonucleoprotein 70 kDa
- Serine/arginine-rich splicing factor 3
- Transformer-2 protein homolog beta
- Heterogeneous nuclear ribonucleoprotein A1
- Protein mago nashi homolog
Sequence:
MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT
Protein: Homoserine O-acetyltransferase (EC 2.3.1.31) (Homoserine O-trans-acetylase) (Q9Y875)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Homoserine dehydrogenase
- cystathionine gamma-synthase
- Cystathionine beta-synthase
- alanine--glyoxylate transaminase
- Threonine dehydratase
- Tryptophan synthase
- Serine hydroxymethyltransferase
- Pyridoxal-phosphate dependent enzyme, putative
- L-serine ammonia-lyase
- L-serine ammonia-lyase
Sequence:
MTTEQPTARLQRVDSQPENPFSALIEDQSIVIIPTFTLESGVTLYNVPVAYTTRGTLSPSGDNALVICHALSGSADVADWWGPLLGGPGQAFDISRFFVVCLNSLGSPYGSASAVTYKDGNPEKGLYGPEFPLTTVRDDVRIHKMVLDDLGIKQIAAVVGGSMGGMLTLEYAYFGKDYVRAIVPIATSARHSAWCISWGEAQRQSIYSDPKYENGYYSFDEPPAAGLGAARMSALLTYRSRNSFESRFGRNVPDPSKRQNINGTERLPTPPNEHWAIHNDGHKGNWSGRNSPAPEKPAEKTEVQYMDPQFSGTKTFSKSVSTTDGNAQKRPATYFSAQSYLRYQGDKFVKRFDANCYIAITRKLDTHDVSRHRARPDSENPVREALSQIQQPALVLGIESDGLFTFEEQKEIAEGIPDSRLKRIDSPEGHDAFLLQFEQVNQYILEFFREVLPDIMSKTPTDGAAIDGVGKLTKSSTFGEAEVEDITAW
Protein: Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3) (P19105)
Organism: Homo sapiens (Human)
Function: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity).
Interaction partners:
- Myosin light polypeptide 6
- Myosin light chain kinase 2, skeletal/cardiac muscle
- Myosin-9
- Myosin light chain 6B
- Myosin-10
- Myosin light chain kinase, smooth muscle
- Myosin regulatory light polypeptide 9
- Myosin-14
- Myosin-11
- Actin, cytoplasmic 1
Sequence:
MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
Protein: Peroxisomal membrane protein PEX14 (Peroxin-14) (Q38CL4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Peroxisome membrane {ECO:0000256|ARBA:ARBA00046271, ECO:0000256|RuleBase:RU367032}.
Interaction partners:
- Peroxisome targeting signal 1 receptor
- Peroxin-13
- Peroxin 19
- Peroxisome assembly protein, putative
- propanoyl-CoA C-acyltransferase
- Nonspecific lipid-transfer protein, putative
- Peroxin-7
- Peroxisomal ATPase PEX6
- RING-type E3 ubiquitin transferase
- Peroxisomal ATPase PEX1
Sequence:
MSLLLSGVVDDGKSKPEVEHTHSEREKRVSNAVEFLLDSRVRRTPTSSKVHFLKSKGLSAEEICEAFTKVGQPKTLNEIKRILSERPYVPTGPNSQHMTQPLRDESADSVPTPHPNQSRRHTSLLYAPQAPPLPEAAAATRGVDWRDLVIGAGAAVIGGFAAFKAFQLYSPYEIRLKDEGSKPRSRRSRRGGRHASSDSEAERSLVHREVPALPVPAIPVASESHVDAKQAEIERLKTELKETQEALEAEKKGKAELSITLGKLRGQVTAYSRTNEKQESQIKSLQEEVNRLKSEIERKEDSAKVNANSNVEETLDSKEEGLPSSDTESSNPNGASSEVARDTQQQDGPAPLSTETDGTVVGGEAA
Protein: [histone H3]-trimethyl-L-lysine(9) demethylase (EC 1.14.11.66) (A2RRT0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAGVGASAPANPACKIMTFRPTMEEFKDFNQYLVYMESQGAHRAGLAKVIPPKGWKPRRNYDDIDDFVIQAPIQQMVAGQSGLFTQYNIQKKPLTVQEFRRLANSDMYCTPRYLNYEDLERKYWKNLTFVSPIYGADVSGTLYDEDIEEWNIGHLNSVLDVIEEDCGVSIQGVNTPYLYFGMWKTSFSWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPNSFKSCEAFLRHKMTLISPSVLKKYSIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFASIRWIDYGKLATQCTCSKDMVKISMDPFVRRFQPDRYELWTQGKDSCSLDHTLPTPSTTPELQSWLQRRRRKTPSTSLHAPRSCSKRLKTVDSAPVKGSGRRSRSAALTAKNKEEEEEDPVKHQKESQYSSELKGLAGRQMCVVKVTRVESDLLAQSTRQVKEASPERLLTPTLTTTSSQNDPDVGHTSSQTSLILDEGQVSKNTNSTAQSEPESTSESDIIVDVTLGSERTAKNPNQTLNCESVLETIAPSIPVTHSLTLHSTGATVLFSESDSQQAKIETEETVIDTLTEDSIDCGTSALYKEQSSISLDPALQGSEPSMNRTNSEIQTTPFCEMPLLMPELIEERVNPQCLAPEMPSLTLAIRPDSANHQPYNSAPILHLEKSHSPPVITDEVRGCSERACPDWPFILPKEGVSQSHKSISDSFKAKPTSASFAPQWGTPEESKQEGNIHKCTSTDQNTQHESISNCTTPTRSILQSSATTHMDFIDSKMVEGVGKETSQRIEEQSSSLTSSQSNFAESKPFTIWKNLSSDNPAVLIESLQPELVVGLTADYAHDSLPYTMWSESGCQQEKFSDSPNSSPHTQTWTNLEPIPMQCSDTEVSENAPLDLKQENEEVEPAEACELNEQAGSQEPQEREFKIQEYYRSVKSEHDGSVSDSDSCESGDKGADSSSESSEENPMSDPEYVETGLEPGEVCTYHMQTVKKTAKSWRHPLRKPTARAVPSAVKQQAASDDEVIEECASEEDEPETEEWAKPLVHLWQHRKAHFQYEQEYNMTAAKNAPHCAVCTLFMPYHQPENLEERRPEVSMGSCSLDAGSRSRPLIPEICFAYQEGPCPLNTLLEEDGSSPLVVCSSCCVQVHASCYGVSAQDVGPVWTCDRCVSEDLAAGCCLCNLRGGALKRTSDDRWVHVMCAVGLPEVKFIDVVKRAPIDISAVPVQRYKLKCIYCRNRIKRLSGACIQCSCGRCPTSFHVTCAHAAGVPMEPDDWPYVVFITCHRHQSRSSSAKVKVSKSELEVGQTVISKHKNLRYYSSRITQVTAQTFYEVMFDDGSFSNDTFPEDIVSRDCALLGPPEVGETVQVKWPDGLLYGAKYLGSNTSYMYQVEFEDGSQVLAKREDIYTLNEDLPKKVKGRLSTASSMRFQDAFFTTQGERKRRRTPNSRFQTDYIAHISPRTFARLSETRSKAN
Protein: Serpin family H member 1 (E9PNX1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNA
Protein: Rhea, isoform G (M9PBW9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSTLSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQGVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKRKIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVESLAHPGIMRPYDASGHPMFYKTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASHPDEVDTEAISASVSQIAQTIPEVTKEVRLIAALMENDTSGDQLLEAARNLCSAFSDLLKAAEPESKEPPQHLINAASRVGEATTHVLSTIAEEEVPENRDLHDMLLALAKAVANTTAALVLRAKNIAASCDDEQARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNEASNDPKLKADLLAAARDVSKSLTDMLEHVKLSSREHANRTSTELSPVENVIIGTDILVSTHDPQEMVRHARTLGQTTAQLIQSIKGEADQQQDADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDSDNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVADTIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTDIPSATQLSKGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLSSVLHNQRSYAGAAGRDTALALGDFTRSVHGVAATTQNPAIIDCADDVVTSSARLIEQAQRTLQGASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMSEFPPSSRPYATLQSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEEEVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAKNLLHAAARGVTESINQLVDASIQSAPGQKECDNAMRNIEALRLMLDYPHEPINELGYFDCVEQATGKSRNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHPSSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQMISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSRERLVDPLLEAVKAVRQYASSSEFSSVPAKISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAVNAQGLSQRRDNNLHGFSGQTMNSASELIDKLEPIRMAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQSLLNASYSDTFVDYQTRMVARAKEIASLANEMNAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQKEIARSAREVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMFATAGTLHSDGDGSFADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQPDSQVMVINAVKDVASALGDLINCTKLASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATVEAISQEIRAMHSPPPVGNTQVGPEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAISEMLIVCRSVAWNCAETEELRSRTLEAGTAVGESYRDLLSGILHNCSADDRMHLSRRVAKCVTDLVAMARLLKGSDWIDPEDPTVIAENELLGAAASIDAAAKKLASLRPRRQADVKIELDENMKFDEMILEAAKGIMGASAALVRAANAAQRELIDTGKVARRPLTSSDDGQWSEGLISAARLVAAATHSLVEAAQNLVRGVGTEEMLISTAKQVAASTAQLLIACKVKSNPNSEAGRRLQAAGNAVIKSTDNLVHSAQQGLEAEEEHSLKINTSMVDGMAQEINARSAVLRKEKELEEARQLLKNVRHAQRYAKNAQGFTTDESDTEYAYRSQNNTLGRSGYYGSSEMPSSPSYLSGGQQQKHHYNHASPQPQHFHHPGAVSPPPSNYPPMDDPNGDFPPPPPPLSTTISNMQTATSGHSFRPNPKLTANAVPRPYPGSPGGSNGLISAPTTTGTPTNTNYQQSYESSSIKTLNSSPPAVPKKPTVNRNLAACVQDLHDKTFGQGGVVQLTGGNGYPGQNYEGYTSRYETRNFDKSANNTTSSSSELGAVKPLESSFSQMTLNTDGGKISIVDQGSERLTSMTQRVMERKSFTTTTESRSETKTEKHSFRLD
Protein: Kinesin heavy chain (O70402)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
SRSHSIFLINMKQENVETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEA
Protein: Kinetochore protein Nuf2 (Cell division cycle-associated protein 1) (Q7ZW63)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular location: Nucleus {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes to kinetochores from late prophase to anaphase. {ECO:0000250}.
Interaction partners:
- Kinetochore protein NDC80 homolog
- Kinetochore protein Spc24
- Kinetochore protein SPC25
- BUB1 mitotic checkpoint serine/threonine kinase
- Dual specificity protein kinase Ttk
- Kinesin family member 11
- Centromere-associated protein E
- Kinetochore scaffold 1.
- DSN1 component of MIS12 kinetochore complex
- Kinesin-like protein
Sequence:
MSENTFPVYKVDVIVQFYRTEVLTGQESKHFTKNDLTPTPKPESVQRLYMRILQLLFRFRPECHYTVPLSENIQYPMLYESFAPIMSVYMRMCQFLPVCRVYDFSLSDLLNPKTKRTITILSAIQNFLHFRKQRLEITAAHQQSFRADMDRLQAYTREIKEAEKKIEKLTTIPPEQQAEAKELASALAELSTNTQHEYQDVSAINEKVAQFKTEIAELSQKLTQRKVEVATLKDEISKLKSQIVESPEELKNEMERMRETAKNIKMSKELADERLVELQMLVQCASQVEAEIQILLKQLQDLQSSMSKTKQRKEEVQSLEVMNESLQKELKSLSSEEAQLKRALTMKLDKESKQQIRRQKKKEVKDQQVKNIYGQYDKMHQKRQEIVKKIEECNRETKQFKEKMQALRENCNQRTQKAQEIYERLLTTLEQYHKRIEKILVETNADALKMKSHF
Protein: ADP/ATP translocase (ADP,ATP carrier protein) (Q5B5W6)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000256|RuleBase:RU368008}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU368008}. Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
- ATP synthase subunit beta
- Mitochondrial outer membrane protein porin
- mitochondrial processing peptidase
- Mitochondrial import inner membrane translocase subunit TIM22
- Mitochondrial import inner membrane translocase subunit tim9
Sequence:
MASQSDKSVLGMPGFVVDFLMGGVSAAVSKTAAAPIERVKLLIQTQDEMLRSGRLDRKYNGLMDCFRRTTQAEGVVSLWRGNTANVIRYFPTQALNFAFRDTYKSMFAYKKDRDGYAKWMAGNLASGGMAGATSLLFVYSLDYARTRLANDAKSTKGGGERQFNGLIDVYKKTLASDGIVGLYRGFGPSVLGIVVYRGLYFGMYDSLKPVVLTGALEGSFLVSFLLGWGVTTGAGIASYPLDTVRRRMMMTSGEAVKYSSSFDAFRQIIAREGVKSLFKGAGANILRGVAGAGVLSIYDQVQLILFGKKFK
Protein: GDT1-like protein C186.05c (Q9P7Q0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Calcium-transporting ATPase 1
- Vacuolar calcium ion transporter
Sequence:
MINVESPLNLETTLGSLQFSHGSVQNIGMSISMIIGCELGDKSFIVTALLAYQYGRASVFFGSYLALFFMTSFAVLVGRAAPFLFPKSITHILGGTLFLIFGVKMLKESKEVRESQQSLENEFDKVEKIIVNEEDMKKTLELGLPASNRSSSTLKDKFFKVFSMSCFKNLFSKKFSRAFIKAFALIFVSELGDRSQIATIVMSAKEKVLDVFIGVNIGHMLCTMVAVIVGRYISNKIEMYKVLFFGGIVFMIFGILYIFQGF
Protein: Phytoene desaturase (neurosporene-forming) (EC 1.3.99.28) (3-step phytoene desaturase) (Phytoene dehydrogenase) (P17054)
Organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Function: Converts phytoene into all-trans-neurosporene as the major product, via the intermediary of phytofluene and zeta-carotene, by the introduction of three double bonds. Both intermediates, phytofluene and zeta-carotene, can be used as substrates and converted to neurosporene. 1,2-epoxy phytoene is also a suitable substrate whereas the C30 diapophytoene is not.
Interaction partners:
- Phytoene synthase
- Acyclic carotenoid 1,2-hydratase
- Phytoene synthase family protein
- Spheroidene monooxygenase
- Protein CrtK
- Magnesium-chelatase 38 kDa subunit
- Geranylgeranyl diphosphate synthase
- 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase
- Magnesium-chelatase 60 kDa subunit
- Geranylgeranyl diphosphate reductase
Sequence:
MSKNTEGMGRAVVIGAGLGGLAAAMRLGAKGYKVTVVDRLDRPGGRGSSITKGGHRFDLGPTIVTVPDRLRELWADCGRDFDKDVSLVPMEPFYTIDFPDGEKYTAYGDDAKVKAEVARISPGDVEGFRHFMWDAKARYEFGYENLGRKPMSKLWDLIKVLPTFGWLRADRSVYGHAKKMVKDDHLRFALSFHPLFIGGDPFHVTSMYILVSQLEKKFGVHYAIGGVQAIADAMAKVITDQGGEMRLNTEVDEILVSRDGKATGIRLMDGTELPAQVVVSNADAGHTYKRLLRNRDRWRWTDEKLDKKRWSMGLFVWYFGTKGTAKMWKDVGHHTVVVGPRYKEHVQDIFIKGELAEDMSLYVHRPSVTDPTAAPKGDDTFYVLSPVPNLGFDNGVDWSVEAEKYKAKVLKVIEERLLPGVAEKITEEVVFTPETFRDRYLSPLGAGFSLEPRILQSAWFRPHNASEEVDGLYLVGAGTHPGAGVPSVIGSGELVAQMIPDAPKPETPAAAAPKARTPRAKAAQ
Protein: Cadherin-2 (Neural cadherin) (N-cadherin) (P10288)
Organism: Gallus gallus (Chicken)
Function: Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion. Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development (By similarity). Required for proper neurite branching, and pre- and postsynaptic organization.
Subcellular location: Cell membrane {ECO:0000269|PubMed:1638632, ECO:0000269|PubMed:2831236}; Single-pass type I membrane protein {ECO:0000255}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P15116}. Cell junction {ECO:0000250|UniProtKB:P15116}. Cell surface {ECO:0000250|UniProtKB:P15116}. Cell junction, desmosome {ECO:0000250|UniProtKB:P15116}. Cell junction, adherens junction {ECO:0000250|UniProtKB:P15116}.
Interaction partners:
- Catenin alpha-2
- Plakoglobin
- Actin, cytoplasmic 1
- Cadherin-1
- Neural cell adhesion molecule 1
- Protocadherin-19
- Tyrosine-protein phosphatase non-receptor type 1
- Vinculin
- Gap junction alpha-1 protein
- Cell division control protein 42 homolog
Sequence:
MCRIAGTPPRILPPLALMLLAALQQAPIKATCEDMLCKMGFPEDVHSAVVSRSVHGGQPLLNVRFQSCDENRKIYFGSSEPEDFRVGEDGVVYAERSFQLSAEPTEFVVSARDKETQEEWQMKVKLTPEPAFTGASEKDQKKIEDIIFPWQQYKDSSHLKRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKSLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIASFHLRAHAVDVNGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAQNGMLRYRILSQAPSSPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDVIVANLTVTDKDQPHTPAWNARYQMTGGDPTGQFTILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSITVIDVNESPYFVPNPKLVRQEEGLLAGSMLTTFTARDPDRYMQQTSLRYSKLSDPANWLKIDPVNGQITTTAVLDRESIYVQNNMYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVNPKEATTCETLQPNAINITAVDPDIDPNAGPFAFELPDSPPSIKRNWTIVRISGDHAQLSLRIRFLEAGIYDVPIVITDSGNPHASSTSVLKVKVCQCDINGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRLDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD