wanglab/gogpt-training-data huggingface dataset:
Protein: REH2-associated factor 2 (Q584U2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: May play a role in mitochondrial mRNA editing by facilitating the association of the gRNA-binding (GRBC) complex with the RNA editing core (RECC) complex. However, appears to be dispensable for mRNA editing per se.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:26769962}.
Interaction partners:
- RNA editing associated helicase 2
- REH2-associated factor 1
- Mitochondrial RNA binding complex 1 subunit
- RNA-editing ligase 2, mitochondrial
- RNA-editing-associated protein 1
- RNA editing complex protein MP61
- RNA editing 3' exouridylylase MP99
- RNA editing complex protein MP67
- RNA editing complex protein MP46
- MP18 RNA editing complex protein
Sequence:
MFRWSWCRLIISKVSAESYVDYLQNSDRELPALSEIFPRHGTGTGELVKFHSLLCEAMKDHNFNYVGIKVVPPTSPPLQCLRATEPVCVPIFSNSFQGSVFSAKQHRIQFVEPLFVIRLGRDPPTQLTANTVPAVCDAFFPGVEFVGSRYPFYPPHTTGFAADLGGCVAVHLGEAVSLGSASLESLGDTNFVVTRREEPIQVGAGKNCLGGPGAAVALAVSYAASMGWPLREKHYIFCSGVGSRSPALAGEYKVNYGAYGSVSASLT
Protein: Solute carrier family 24 member 4 (D3ZCC3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MEDRFSVNSTHHVSIALMLCSDGSAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAVSHPSHPSVGWWEGLILIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSFDDPSVPLLGQVKEKPPYGKSPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPPPQPPPPEPESVETVFLSPFSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMCREDD
Protein: Probable TonB-dependent receptor (Q9I6Y1)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell outer membrane {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}.
Interaction partners:
- Probable sigma-70 factor, ECF subfamily
- Probable transporter
- Secretin/TonB short N-terminal domain-containing protein
- Probable transmembrane sensor
- Probable tonB-dependent receptor
Sequence:
MTPFPRFALRTLPALFLSLGCLAATVQAAEAVRYRFSQAAAPLAQALNAFSRASGQTLLYTAELPPQATAPALHGSLVAEEALQRLLQGSGLRARRIDERTLTLEPIPASGALDLDATTVSAAAPAQGYRPAANASISRGDAPVLEIPQAISVVPAQALQDQRPRNLDDALGNISGITQANTLGGTQDAVMKRGFGDNRDGSIMRDGMPSVQGRNFTATADHVEVLKGPASLLYGIQDPGGVVNVVSKKPQLQQANALTLRGSAYAHGRNGSGGQLDSTGPLGDSGLAYRMILDHEDEDYWRDFGKSRETLVAPSLAWYGEDTTVNLSYEHREFTTPFDRGTAIDPRTNRPLDIPRSRRLDEPFNITEGRSELTRLDLERQLDDTWKAHFGYGYSRETYDDNQARVMAVNADGTLTRRMDGTHGAVSSDSFTTLGLSGTLQLAGMQHDLQFGMDHEKRKIFRADLLRDSKTSRFDYLDPVYGQVVPSTRVVAGDSDQTDKLRSDSLYFQDSIHLDERWILVGGARYQIYDQLAGRGRPFNANTDINGQKWVPRGGLVYRLSDEVSLYGSYMRSFKPNSTIAPLSTGETIDSAILPEEATSWELGAKLDVPGRLSGTLALFDIRKKNVLVNELDGAGNSSVRAAGRVRSRGLELDLTGQLSERWSLIGSYAWLAAEVTEDPTLEGKRLQNVARNTASLSAVYELGQLFGGDRLRLGGGARYVGKRPGDPANSFDLPSYTVADAFASYDTRFGGHGVKFQLNVKNLFDRTYYPSSANRLYVAMGEPRQFQVSTTVEF
Protein: PRKR-interacting protein 1 (Protein C114) (Q9CWV6)
Organism: Mus musculus (Mouse)
Function: Required for pre-mRNA splicing as component of the spliceosome (By similarity). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9H875}. Nucleus, nucleolus {ECO:0000269|PubMed:12679338}.
Interaction partners:
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor SLU7
- Splicing factor Cactin
- Protein FAM32A
- Splicing regulator SDE2
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein G
- THO complex subunit 4
- U2 small nuclear ribonucleoprotein A'
- Spliceosome RNA helicase Ddx39b
Sequence:
MASPAAASVRPPRPKKEPQTLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMNEWAPRAPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQKEEPSQCQEQHASSSDEASETEEEEEEPSVVIMGR
Protein: DNA polymerase nu (EC 2.7.7.7) (A5X572)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MESYLCSSLNAVPLSAAAQRIISALRVQYVQKADRSRATWSDQGFGMAQQQDGEDRNVELHSGNSRDLNLNELAEHSNSSELEDMAIDKFALNLPIIERFVFDHADNIITPIGQHFTPSVQGEDSLQTFCLTSMGSPQARADVITQSEIHGRTFRKRKWIQPASPPEQDLVGCSQPETPPMKKFNFMLPIDNCQPAFGEEGKMIDIVDKRNNNGQPWLPEKENSDSVSEDRAAFIEVQLGSLRCISNVDMITSKCVLETSHYWEESRNCQLSVPMENSPDAKRCESISVFECQQDTANRSDKMMDSSREKVDNGTERRDITKLRTSSPQSDDNTVVMPVLEGEMECAASSSRNAMQHSIQPHSQAVEVTSFSKHAGKWEPPGPSQKALCKKTFRNPRFPIQLFHQVNGSMRLLKQRKAPQPMVKRQRRLLRPQKIFKSKRGKKQNKLTKTSDSSLSGSKESSHILSETDRKEDGTTTTLKGAFSLISDPRVCDTGRVSQEERECILEETGKAKAFVVTMVYQDGTTQLDSEQKLCPPVCGLLILLKSELNSEEPLERPPERVLYLRLEQTPAWAQQDFTQKQDAYAREMLLKIMCGTKTFVCFKAKDLLRTVLRHFRDLSWTQVLGCQVMDPQIAAWLLDPADSSSCFQTLLSKHYTHQFTPTTLQPVLEQAKVTQVISNLSLLHKLMEELHYKLRTQGLWQLYSGIEQKMIPVLAAMESYKMHVDKEALKKTSEMLGSKLKQLEQEAHQAAGQKFLVSSSAQLRLILFEKLRLHELCENKKLPKTVKQQQSTSETALLQLQKLHPLPKIILEYRQIHKIKTTFVDGILSCTRKTFISSTWNQTSTVSGRLSAKHPNFQALPKLPLQISKKQYIHGKASDIVTVHPRAMFIPREGWTFLSADFCQVELRLLAHLSADPQLLRIFQSPEADAFTMLAAQWKGVSEDRVSLEDREQAKRIVYSVVYGAGRERLSGILGVSAEEASRFQDSFLKTYREVPAFIQHTIQHCQSHGFVRSIMGRRRFLPHIHSADWSLRNQAERQAVNFVLQGSAADLAKLAMIRICSQVSSDSQTARLVAQIHDELLFEVEISQLDQFAALVKKTMESLQHIEYLNVNLSVPLKVLLSTGRSWGSMYEMNLSCTATATSA
Protein: Zona pellucida-like domain-containing protein 1 (ZP domain-containing protein 1) (Cupulin) [Cleaved into: Zona pellucida-like domain-containing protein 1, secreted form] (Q8BGZ8)
Organism: Mus musculus (Mouse)
Function: Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ.
Subcellular location: [Zona pellucida-like domain-containing protein 1]: Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:C0H9B6}; Single-pass type I membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Zona pellucida-like domain-containing protein 1, secreted form]: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:C0H9B6}.
Interaction partners:
- BRICHOS domain containing 5
Sequence:
MERVWLLFLLAIRVSPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATTVQIGNISGYIDTPDPPAVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDTRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVLCFSLLLCSLALLHRKGSTSLVLNGVRNPVFE
Protein: Oct binding factor 1 (POU class 2 homeobox associating factor 1) (Q90ZH6)
Organism: Gallus gallus (Chicken)
Interaction partners:
- Uncharacterized protein
- Paired box 5
- POU domain, class 2, transcription factor 1
- B-cell antigen receptor complex-associated protein beta chain
- Joining chain of multimeric IgA and IgM
Sequence:
MHWQKSSASEQQPQPRPYQGVRVKEPVKELLKRKRGNVHNATAAAATTVVLPHQPLPSYSPMGQPCIDVDAAAPALPGAEEGALCSSWLSQPSPSSLQPLTQWTTYPDYVSHEAASCPYTADMYIQPMCPSYTLVGPSSVLTYASQPLITNFTPRSSTPAVVPQLEVTEQQPPLTYFPWAQPLSALPAPTLQYQPASSTLPTPQFVPLPISIPEPAPQELEDARRVIGTLPIEKLLLEDEDNDTYVLNHALSVEGL
Protein: Callose synthase 9 (EC 2.4.1.34) (1,3-beta-glucan synthase) (Protein GLUCAN SYNTHASE-LIKE 10) (Q9SFU6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in sporophytic and gametophytic development. Required for normal plant development. During pollen formation, required for the entry of microspores into mitosis and microspore symmetric division. May be required for correct temporal and spatial control of callose deposition during pollen mitosis. During plant growth and development, callose is found as a transitory component of the cell plate in dividing cells, is a major component of pollen mother cell walls and pollen tubes, and is found as a structural component of plasmodesmatal canals.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Maternal effect embryo arrest 18
- Translocon-associated protein subunit alpha
Sequence:
MSRAESSWERLVNAALRRDRTGGVAGGNQSSIVGYVPSSLSNNRDIDAILRAADEIQDEDPNIARILCEHGYSLAQNLDPNSEGRGVLQFKTGLMSVIKQKLAKREVGTIDRSQDILRLQEFYRLYREKNNVDTLKEEEKQLRESGAFTDELERKTVKRKRVFATLKVLGSVLEQLAKEIPEELKHVIDSDAAMSEDTIAYNIIPLDAPVTTNATTTFPEVQAAVAALKYFPGLPKLPPDFPIPATRTADMLDFLHYIFGFQKDSVSNQREHIVLLLANEQSRLNIPEETEPKLDDAAVRKVFLKSLENYIKWCDYLCIQPAWSNLEAINGDKKLLFLSLYFLIWGEAANIRFLPECLCYIFHHMVREMDEILRQQVARPAESCMPVDSRGSDDGVSFLDHVIAPLYGVVSAEAFNNDNGRAPHSAWRNYDDFNEYFWSLHSFELGWPWRTSSSFFQKPIPRKKLKTGRAKHRGKTSFVEHRTFLHLYHSFHRLWIFLAMMFQALAIIAFNKDDLTSRKTLLQILSLGPTFVVMKFSESVLEVIMMYGAYSTTRRLAVSRIFLRFIWFGLASVFISFLYVKSLKAPNSDSPIVQLYLIVIAIYGGVQFFFSILMRIPTCHNIANKCDRWPVIRFFKWMRQERHYVGRGMYERTSDFIKYLLFWLVVLSAKFSFAYFLQIKPLVGPTRMIVKQNNIPYSWHDFVSRKNYNALTVASLWAPVVAIYLLDIHIFYTIFSAFLGFLLGARDRLGEIRSLEAIHKLFEEFPGAFMRALHVPLTNRTSDTSHQTVDKKNKVDAAHFAPFWNQIIKSLREEDYITDFEMELLLMPKNSGRLELVQWPLFLLSSKILLAKEIAAESNSQEEILERIERDDYMKYAVEEVYHTLKLVLTETLEAEGRLWVERIYEDIQTSLKERNIHHDFQLNKLSLVITRVTALLGILKENETPEHAKGAIKALQDLYDVMRLDILTFNMRGHYETWNLLTQAWNEGRLFTKLKWPKDPELKALVKRLYSLFTIKDSAAHVPRNLEARRRLQFFTNSLFMDVPPPKSVRKMLSFSVFTPYYSEVVLYSMAELTKRNEDGISILFYLQKIYPDEWKNFLARIGRDENALEGDLDNERDILELRFWASYRGQTLARTVRGMMYYRKALMLQSYLERKAGNDATDAEGFELSPEARAQADLKFTYVVTCQIYGRQKEDQKPEAVDIALLMQRNEALRIAYIDVVDSPKEGKSHTEYYSKLVKADISGKDKEIYSIKLPGDPKLGEGKPENQNHAIVFTRGNAIQTIDMNQDNYFEEALKMRNLLEEFDRDHGIRPPTILGVREHVFTGSVSSLASFMSNQETSFVTLGQRVLAKPLKIRMHYGHPDVFDRVFHITRGGISKASRVINISEDIFAGFNTTLRQGNVTHHEYIQVGKGRDVGLNQIALFEGKVAGGNGEQVLSRDVYRLGQLLDFFRMMSFFFTTVGFYLCTMLTVLTVYIFLYGRAYLALSGVGATIRERAILLDDTALSAALNAQFLFQIGVFTAVPMVLGFILEQGFLQAIVSFITMQFQLCTVFFTFSLGTRTHYFGRTILHGGARYQATGRGFVVKHIKFSENYRLYSRSHFVKAMEVILLLVVYLAYGNDEAGAVSYILLTVSSWFLAVSWLFAPYLFNPAGFEWQKVVEDFKEWTNWLFYRGGIGVKGAESWEAWWEEELSHIRTLSGRIMETILSLRFFIFQYGIVYKLKLQGSDTSFAVYGWSWVAFAMIIVLFKVFTFSQKISVNFQLLLRFIQGLSLLMALAGIIVAVVLTPLSVTDIFACVLAFIPTGWGILSIACAWKPVLKRMGMWKSIRSLARLYDALMGMLIFLPVALCSWFPFVSTFQTRMMFNQAFSRGLEISLILAGDNPNSGL
Protein: DNA replication protein 1 (Gene product 1) (gp1) (P03679)
Organism: Bacillus phage phi29 (Bacteriophage phi-29)
Function: Protein that assembles into highly ordered structures and provides a specific site for viral DNA replication. Probably anchors the viral DNA replisome to the host membrane.
Subcellular location: Host membrane {ECO:0000269|PubMed:11032825, ECO:0000269|PubMed:12904294}; Peripheral membrane protein {ECO:0000269|PubMed:12904294}.
Interaction partners:
Sequence:
MGKIFDQEKRLEGTWKNSKWGNQGIIAPVDGDLKMIDLELEKKMTKLEHENKLMKNALYELSRMENNDYATWVIKVLFGGAPHGAK
Protein: Immunity-related GTPase family M protein 1 (EC 3.6.5.-) (Interferon-inducible GTPase 3) (Interferon-inducible protein 1) (LPS-stimulated RAW 264.7 macrophage protein 47) (LRG-47) (Q60766)
Organism: Mus musculus (Mouse)
Function: Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate pro-inflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:15294976, ECO:0000269|PubMed:15908352, ECO:0000269|PubMed:20072621, ECO:0000269|PubMed:24751652}. Cell membrane {ECO:0000269|PubMed:15294976}. Cytoplasmic vesicle, phagosome membrane {ECO:0000269|PubMed:15294976, ECO:0000269|PubMed:19620982}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:15294976}. Lysosome membrane {ECO:0000269|PubMed:17982087, ECO:0000269|PubMed:20072621, ECO:0000269|PubMed:27098192}. Late endosome membrane {ECO:0000269|PubMed:20072621}. Mitochondrion membrane {ECO:0000269|PubMed:24751652}. Lipid droplet {ECO:0000269|PubMed:23785284}. Cell projection, phagocytic cup {ECO:0000269|PubMed:15294976}. Note=Behaves like an integral membrane protein (PubMed:15294976). Recruited to the plasma membrane around forming phagocytic cups, it remains associated with maturing phagosomes (PubMed:15294976). Association with phagosomes is dependent on nucleotide-binding but is IFNG-independent (PubMed:15294976). Also detected in late endosomes and lysosomes: lysosomal localization is IFN-gamma-induced during bacterial infections such as S.typhimurium infection (PubMed:17982087, PubMed:20072621). Associates with lipid droplets and 'self' cytoplasmic vacuoles, while it does not coat 'non-self' pathogen-containing vacuoles (PubMed:23785284). {ECO:0000269|PubMed:15294976, ECO:0000269|PubMed:17982087, ECO:0000269|PubMed:20072621, ECO:0000269|PubMed:23785284}.
Interaction partners:
- Autophagy protein 5
- Ubiquitin-like-conjugating enzyme ATG10
- Immunity-related GTPase family M protein 2
- Autophagy-related protein 16-1
- Guanylate-binding protein 3
- Signal transducer and activator of transcription 1
- Guanylate-binding protein 2
- Nucleotide-binding oligomerization domain-containing protein 2
- Beclin-1
- Guanylate-binding protein 7
Sequence:
MKPSHSSCEAAPLLPNMAETHYAPLSSAFPFVTSYQTGSSRLPEVSRSTERALREGKLLELVYGIKETVATLSQIPVSIFVTGDSGNGMSSFINALRVIGHDEDASAPTGVVRTTKTRTEYSSSHFPNVVLWDLPGLGATAQTVEDYVEEMKFSTCDLFIIIASEQFSSNHVKLSKIIQSMGKRFYIVWTKLDRDLSTSVLSEVRLLQNIQENIRENLQKEKVKYPPVFLVSSLDPLLYDFPKLRDTLHKDLSNIRCCEPLKTLYGTYEKIVGDKVAVWKQRIANESLKNSLGVRDDDNMGECLKVYRLIFGVDDESVQQVAQSMGTVVMEYKDNMKSQNFYTLRREDWKLRLMTCAIVNAFFRLLRFLPCVCCCLRRLRHKRMLFLVAQDTKNILEKILRDSIFPPQI
Protein: Probable two-component response regulator (G3XD16)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Sensor protein
- Sensor protein
- Sensor protein
- Sensor protein
- histidine kinase
- Sensor protein kinase PmrB
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
Sequence:
MRILIIEDEVKTADYLHQGLTESGYIVDRANDGIDGLHMALQHPYELVILDVNLPGIDGWDLLRRLRERSSARVMMLTGHGRLTDKVRGLDLGADDFMVKPFQFPELLARVRSLLRRHDQAPMQDVLRVADLELDASRHRAFRGRVRINLTTKEFALLHLLMRRNGDVITRTQIISLIWDMNFDNDSNVVEVAICRLRAKIDDGFDLKLIHTIRGVGYVLEARR
Protein: alanine transaminase (EC 2.6.1.2) (A0A8I6ACI1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MRVNLGRFAMQRAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPERSPRDRILTLESMNPQVKAVEYAVRGPIVLKAGEIEMELQRGIKKPFTEVIRANIGDAHAMGQQPITFLRQVMALCTYPNLLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFITRRDGVPADPDNIYLTTGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEDNCWALNVDELRRALRQAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYQMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVPGEESFEQFTREKESVLGNLAKKAKLTEDLFNQVPGIQCNPLQGAMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLHKVKDFHLKFLEKYS
Protein: PDGF- and VEGF-receptor related, isoform A (EC 2.7.10.1) (Q9VLQ8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MAMLPRLILLPLLLILRISWSDAVPLQQFSPDPDDSIENCGGENGAPLMTPCKSAIILDAQTSTTLKCEDDEPMSWWTSQSQYVHVKSFDNTEDPARPFGTSLHLIEVTADYVAAYYCVKTSKFSQIAKEEQSDEAMIELVNQGYASSIYVYVNDPDTKLVDSHNVVTARQYTDVVIPCKPAMPDTEVLLETSNGESTWKISSKGQIQGNPKFFDSVRYHPRWGFTFRVIDCVSGYLYCKTLDYELIIDVTYPEKDGKPLPKPVIRSSVEHHVFTDTNFTLDCEQSAYVESVYGMEWFTPSRDENRIFASQSRTDPKTRNSTHQTGRSTLTVLNAQPSDTGLYKCVTTDNSNQNVQRATYRIKVLKQNESYLNVGEPSGHYNVQEYANRTIQMTANFEGFPTPSFSWFKPDGTEVRQSENNFKILSTELSTMLQVLNAQLQDSGTYVLRGSNSFGVVQREYNVSVMDAPALKMSDAYVQVGSVARLECTVRSYPPAIVTFFFRPCSLEPQWPTCSVLNQNFSLPSEQEKYQFQTRPRPGKLSVERIYEVSFLPTEPGILTCIAQNIIDGKERRTLTKAHVLLGNISENMTIYGFDKDHKIAKEDNVNFTCEALAYHFDGNLKWFINGEDLKESDSVHIETSHTKYSYKSTVHITTISDRDRGTYECRAYHNDKDAVYSSREIDLYVHDPSAPQWTNGGQEGHSKIKRKLSQTLELECASTAVPVAIVRWFKDDKEVTESKLRHIIEKESKLLITHLYPGDEGVYKCVVENRLDRIERSFTVVISDLPGISMAWVWFGVILFLILIGLCVFLAVRYQKEHKRHLALKAAGLANFEEGAVGHINPDLTLDEQAELLPYNREFEFPRENLKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVVRALVSELKIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPDTDHIDPSIMTQRMSDNYELHRDTNGGGLKYANVGFPIHSYINEPHNNNTQPPTHRRNSDNDPRSGTRAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTVDLISWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELYEIMLECWRKNPESRPLFAELEKRFANMLGEDVASHYLDLNNPYMQSNIEYMKKQSTDYLALMGSPDELAPAAPRYVNGHIVPDIRIEELPDDYMEMSRDSDPDACTAIFSPTRLEGESSDFPDFSSETTFNFPGARQSPTLSNNLNSGSSKPLRKKNGMPTVDVADQAPEEIPMLHRSSTGSDGSPEQGRRFNQALKQQYVTPTPSPRHHVETKLNGEPSENYVNMKPPRKNIPGKTTTGGGGAAAGASTEAFSNPSYQPLSTVNEKEQRRY
Protein: Prostate stem cell antigen (O43653)
Organism: Homo sapiens (Human)
Function: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.
Subcellular location: Cell membrane {ECO:0000269|PubMed:9465086}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:9465086}.
Interaction partners:
- Glutamate carboxypeptidase 2
- Lymphocyte antigen 6E
- Prostate-specific antigen
- STEAP1 protein
- Mucin-6
- Mesothelin
- Cell adhesion molecule CEACAM5
Sequence:
MAGLALQPGTALLCYSCKAQVSNEDCLQVENCTQLGEQCWTARIRAVGLLTVISKGCSLNCVDDSQDYYVGKKNITCCDTDLCNASGAHALQPAAAILALLPALGLLLWGPGQL
Protein: Dual specificity protein phosphatase 2 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PAC-1) (Q05922)
Organism: Mus musculus (Mouse)
Function: Dephosphorylates both phosphorylated Thr and Tyr residues in MAPK1, and dephosphorylation of phosphotyrosine is slightly faster than that of phosphothreonine. Can dephosphorylate MAPK1.
Subcellular location: Nucleus.
Interaction partners:
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase 1
- Stress-activated protein kinase JNK
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 11
- Mitogen-activated protein kinase 13
- Mitogen-activated protein kinase 12
Sequence:
MPIAMGLETACELECAALGALLREPREAERTLLLDCRPFLAFCRSHVRAARPVPWNALLRRRARGTPAAALACLLPDRALRARLGRGELARAVVLDESSASVAELPPDGPAHLLLAALQHEMRGGPTTVCFLRGGFKSFQTYCPDLCSEAPAQALPPAGAENSNSDPRVPIYDQGGPVEILPYLYLGSCNHSSDLQGLQACGITAVLNVSASCPNHFEGLFHYKSIPVEDNQMVEISAWFQEAISFIDSVKNSGGRVLVHCQAGISRSATICLAYLIQSHRVRLDEAFDFVKQRRGVISPNFSFMGQLLQLETQVLCH
Protein: GAS2-like protein 3 (Growth arrest-specific protein 2-like 3) (Q86XJ1)
Organism: Homo sapiens (Human)
Function: Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21561867}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21561867, ECO:0000269|PubMed:24706950}. Note=Localizes to microtubule and actin cytoskeletons. {ECO:0000269|PubMed:21561867, ECO:0000269|PubMed:24706950}.
Interaction partners:
Sequence:
MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK
Protein: Transcription factor PIF6 (Basic helix-loop-helix protein 132) (AtbHLH132) (bHLH 132) (Phytochrome interacting factor 3-like 2) (Phytochrome-interacting factor 6) (Transcription factor EN 111) (bHLH transcription factor bHLH132) (Q8L5W7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Phytochrome B
- Phytochrome A
- Phytochrome E
- Cryptochrome-2
- Transcription factor bHLH63
- E3 ubiquitin-protein ligase COP1
- At1g17830
Sequence:
MMFLPTDYCCRLSDQEYMELVFENGQILAKGQRSNVSLHNQRTKSIMDLYEAEYNEDFMKSIIHGGGGAITNLGDTQVVPQSHVAAAHETNMLESNKHVDDSETLKASSSKRMMVDYHNRKKIKFIPPDEQSVVADRSFKLGFDTSSVGFTEDSEGSMYLSSSLDDESDDARPQVPARTRKALVKRKRNAEAYNSPERNQRNDINKKMRTLQNLLPNSHKDDNESMLDEAINYMTNLQLQVQMMTMGNRFVTPSMMMPLGPNYSQMGLAMGVGMQMGEQQFLPAHVLGAGLPGINDSADMLRFLNHPGLMPMQNSAPFIPTENCSPQSVPPSCAAFPNQIPNPNSLSNLDGATLHKKSRKTNR
Protein: Helix-loop-helix protein ngn-1 (Q95XG7)
Organism: Caenorhabditis elegans
Function: Acts as a transcriptional regulator (By similarity). Regulates expression of various genes, including homeobox protein unc-42 and helix-loop-helix protein hlh-34. Required for embryonic viability, neuromuscular development, organization of the nerve ring and neuronal cell body location. Regulates AIY neuron axon morphology and cell fate. Plays a role in cell autonomously establishing a neuronal left-right asymmetry. Involved in regulating glial specification.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Helix-loop-helix protein hlh-2
- Transcription factor sox-2
- Helix-loop-helix protein 14
Sequence:
MYHHSPFYPHHLQTGEQDLDMERENDMDQNSKNSTQKPVKREKRRYRCRKRSPATIERAKTVRRDKANARERRRMNSLNDALEHLRGILPALPDEPKMTKIETLRKAQEYIASLSFQLSGGSPDSSQCCETGSCGLCSASQSLQSTPFQSPCFPQPLQYPSSYSNPPSQMYYHHHHQSPSFPHH
Protein: LD02690p (Q5BI03)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Autophagy-related 8a, isoform A
- Rab3 GTPase-activating protein non-catalytic subunit
- TBC1 domain family member 23
Sequence:
MAGICPREAVRVKVKKCEPTARPEWRKFSVDPQITTLEVLYSLLAKAFDVKSDFSIKYKAFDPAGNEIYLAVRSDWDLDAAFLRIHNISIQTASEPCLTLQIDVKPFTVVRECETEASPGRSITGAPAPATPAPFVPARELMSPLQSLGVSQKYVQHMQTKLGSSILNQMEKTFSIVQKAFNLSEEHMANLPPRPPMCDSEFRLFLDALGQIQRKDELHRVIFLGGIDPSLRRVVWKHLLNVYPGGANGLALDGHQRMEFMRRKSEQYCRLRDTWKAAVKRGSVAGELAYVTSMVKKDVLRTDRLHPFYAGSDDNQNIAALFNILTTYALNHPSVSYCQGMSDIASPLLVTMNDEAQAYICFCAIMSRMRGNFMLDGIAMTQKFAHLTEALSFYDPEFWEYLKSQQADDLLFCYRWLLLELKREFPFEDALRMLEVQWSSLRYRCDGEKELALFEKEFVPITDASVPNSASTFSSSYSATPTSPSYLLTKPRESPYTKVCALRRQSSSASLSSLSSSVGTSHGLDNTKRLNHSLDDNMSRHATAAARRQRRTSAKVHQSLDESKMLALIEGALDNRNVKLEQNLSAGEETEDDDVFDRKESPSFLETNPFKDDAQRAPERETTPPVSPGRAFLCSSSSSNLDEDPSDRKAKLQHKNIMTVSNIIAKQLATNASQVSESMKRVSTSSGGHFKDLKEKLAASSRIGISFDGEGEDDGDRKMPPKLVKNFNEFLNFATINKNRISDRFATQPQQTSGPISVTKPVVQLTKSGMGSSLDESDSSSLPETSWSASTAATTIQQAQELSSYNLQLDLESNHPCDPDDSNTPDQDPDQEYYPMTTAITRELRLEAENLDRQVFGLPFTESEKREDIEYEKLDKDALDLVEDLKENEIITCPDVSELHMRRRQRLAAKSNSVQQNESHAFNPFIDESQLMDGHSPLGMRNSNSLPEVILPISTEPSLVEVSPLVEIATNADDESAYTRSPQRSTHLNGVSAVNTTAAALPPPTEFGGGNAFLMFLCLTLLLQHRNTIMKAGMDYNEIAMHFDKMVRKHDVTRVLNQARRMFVDYLKAQSSPQRQRSPSGTVSTGSTGASLTSSMPA
Protein: Transgelin-3 (Neuronal protein 22) (NP22) (Neuronal protein NP25) (Q9UI15)
Organism: Homo sapiens (Human)
Interaction partners:
- WD repeat-containing protein 90
- Lens fiber membrane intrinsic protein
Sequence:
MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM