wanglab/gogpt-training-data huggingface dataset:
Protein: Putative stoned B-like protein (Adaptin-related protein 10) (Uncoordinated protein 41) (P90761)
Organism: Caenorhabditis elegans
Function: Potential adapter protein, which may be involved in endocytic vesicle recycling of synaptic vesicles.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Synaptotagmin-1
- EHS-1
- Intersectin-1
- C2 domain-containing protein
- Phosphatidylinositol-binding clathrin assembly protein unc-11
- Endophilin-A homolog
- AP-2 complex subunit alpha
- AP-2 complex subunit mu
- C2 domain-containing protein
- Transthyretin-like family protein
Sequence:
MSWRDRDFDPHGGRNAFRLTDESKQSSSERAASMRAMRSFTQSIEDEGPPELPASLDIDMIEGVSMKTSDTNDTIIEVKPGKVDPQLGETQKYKMAVPGPGHSEQEQELHKSLIRDEEEDAEVEQVFAASAEPVVTPPKSLNFAETAEELRHAYDQKIRKRPTTPTSACVLDGIAFFAGSVDGSNDTIPTDAEKKIKVSIPSGRRRKTENMSYSEFYESMANQIPGGGGRRMSQSGRTTPLHDYEGDILDENPQYKDKAPPAPVVHRRSSIEWENFADMEDKMEQAEEKARKEEKKEKEETAEVAQNDDVTTEKHQNEVEKSKKMLNFLAKPPTVEITSPDAPHQGAFHDNTPKEPKVVEEEEDDDLPTFSEDMDEARQQVMKEMTESVVKTENVENEKQEDTHISEGHVEYGTEESPAVTDGSYQQDGTENAYDPNAYPGYIWNYETQEWEYDPSYVAPEEPIDQSAYEAQAAAYAEVDQRAAEVVYQREHAGYDQGDFYTHQDTSYSSEAYAHDQAKGYQDPNAYGAEAAADNSQEYDYSAYGGYEGYLAACRAYDEESQQPQYGETVATEAYSQDYGYEQQGDYHHEGVGATDENSTSAISGYEQNGASTSLGYGDAQGYDGYDHNASYYQGQEYQQEYYQNHKYENSQYQVDQHPAESAAPPRPVAPMEPLFKQAPPQPDPFGWDSSGHTGDAPTASEPVQELSPTPEASSSTGTSAPARPPPARPEAPKKDETAVDAAAPPRPPPAARPPPPRPAPANKEKPKEPEPEEDAWAQFKRMTEKVSTAVKSTESTLKNLEETSAANDIKDESYLANVGGSQGFVNESTQKEIQRLTEEKKMEKLQKKKLKQQGKKAATPTLEPDEEDAMDRAAQELAMKMASMRSDMADWKAPEMIPVKEIKKAPEIRRVDSASAIPPRKRSSIKDVQQDSGGSLELPPHLAAPQDSIAPNPKGDHAPDDPILSAPAWADFETSEPMLPPSESGFFSNKDASNEGGVSRDATDDPFVTTVASSEKRSSFVADPFAPQQAALIDESYDPFAVVAVEEVVAMAKAKAEQAAANAENEDDFYNGRQSPTLSTPTPEGGSPISQQRPNAFEDDFKCAELTGLDTPTPLYDEDDSQPLTDFIPKFDGDGWDLMVRHPIKKKSFMAERCWKPCYVRLHGLTLYLYNDKKDAQPIQELLLQATYSLSDTTLQAYDVYGKIHTVKLQFVVYKEKVGIRPGQISRLVDGHITKYGLPLEHSAQCTVLLKFGSLNASHLQTFVTTVEDLLFKCKITRTAKPVYKQDEVQIHCYDEYSAFVDKEGILSDQKARVRLFCLAFLTGSPVLEVGLNDRRRQGKEIVRRKDILPMYTERWIRFEALEFHSIVNKPEFDKEQVIAFSPPDGCFFEIMRFRVRPPRNREKAMTVKSIMKIAGSKVEIRIEAMAAAQIQRTRGSDERRNIPCEDIAIRFPIPEAWIYLFREERHWGVGSIHSKKLRPGKVKNLKDRLLGAVQASEPNLIECAIGEAKYEHVYRSLVWRIPRLPEKHHAAYKSHLLKCRFELSSFDLMPEEFLPRCDVDFTMPLATVSNTVVRSVSVEQHEDSDRVEKFVRYVAKYQYKVEIDYVQCADLDLDMADPSVNPEAAAAPVPELHQPTFNPSTQESDTQQGYRIDFNEAEMGGSNRRDDSSSDEEPDSHKMPIIQIDMKNYGY
Protein: Spermatogenesis associated 24 (H0Y992)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XLGWSKAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNGITCLTSGSRSSRRATWPRCWTRSI
Protein: At4g12670 (Homeodomain-like superfamily protein) (MYB transcription factor) (Q700D7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MLTDKSRKGCRESLGGVDVGLMMEKEAGGVENVVEVNVSGASGMVSGKRREGDGLNNKWIVIEKSQKMQKVAAETHSRENSKADDIDSDKGRKQRGRFNEKNYEISYACISNAGEGRKGRVRRGNEKNHQAPEAHSIDVGGERKRQRRCDDINHEKAQPHSFAVGIKTKEKRRYSEKNQQNKTVATTHEHDVLTNDGRTEARDSDFGEGRSGQGCFHENNQQTKVSSTERCEQEIPRTNKRVSLGSGLGEGRYREGRHIEKNQHTETVKTETHGKEVSKDRKRKRERGVERDGDEFYLAENQDRQCQADMRNDDVAFNKQATGFSTVEQVERKSVSSISSPESTNNVNDPNVAFQELALIIHPKAGVQEQPIEARPLRSVSSKKPSFQPEKYGHKSYLEKNGPASNDPAQSATKRKRRFWTLAEVEMLRVGVQKFPGERNIPWRKILQFGRDVFHDERAPSDLKDKWKTLNKIPSDTGKWVSLSTERQPNYYVSEVSSE
Protein: histone deacetylase (EC 3.5.1.98) (G5EB64)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Kinetochore protein
- Nucleoporin NSP1
- Chromatin modification-related protein eaf3
- sterol 14alpha-demethylase
- WD repeat protein
- Transcriptional co-activator
- Chromatin remodeling complex subunit
- Lysine-specific histone demethylase Aof2, putative
- FAS1 domain-containing protein AN1527
- Asp hemolysin-like protein
Sequence:
MASGTSGPAGPPLDPIDLNVSGDRSKRVAYFYDSDVGNYAYVSGHPMKPHRIRMTHSLVMNYSLYKKMEIYRAKPASKFEMTQFHTDEYIDFLSKVTPDNMDAFAKEQSKYNVGDDCPVFDGLFEFCGISAGGSMEGAARLNRNKCDIAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLRFKQRVLYVDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGELRDIGVGQGKYYAVNFPLRDGIDDVSYKSIFEPVIKSVMEWYRPEAVVLQCGGDSLSGDRLGCFNLSMRGHANCVKYVKSFNLPTLIVGGGGYTMRNVARTWAFETGILVGDNLGSELPYNDYYEYFAPDYELDVRPSNMDNANTREYLDKIRTQVVENLKRTAFAPSVQMTDVPREPLVDGMDDEAEAALDDLDEDENKDKRFTKRRFDQYVEKPGELSDSEDEDENAANGVTRKPAHLKRRNQANYRLDLADSGVESGMATPQDASSVADEEMDTGTDVKITEAPGPEPDSEAQGTSSAAEPPSRAGNGSVDEPSEMIVDSKEPPRSVPVSRPVSPKPTDEDTAMEDADMPVPEVNQENTPEASQATQNKPAEGTPASESAVAKLTSQTKASFESNEGRKQLEPETVKEAGLAAVTTETKDKTPEAPRAGALPAVTAEQETTKQGEPSAEAQPEAAKE
Protein: E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (Q9D9R0)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as RIGI, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53. Acts as a negative regulator of type I interferon production by mediating ubiquitination of RIGI at 'Lys-181', leading to RIGI degradation. Mediates ubiquitination and subsequent degradation of p53/TP53. Mediates ubiquitination and subsequent degradation of JAK1. Acts as a positive regulator of T-cell activation.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q96EQ8}; Lipid-anchor {ECO:0000250|UniProtKB:Q96EQ8}. Note=Shows a reticular staining pattern within the cell and is probably expressed at other intracellular membranes in addition to the Golgi membrane. Not detected at the plasma membrane. {ECO:0000250|UniProtKB:Q96EQ8}.
Interaction partners:
- Antiviral innate immune response receptor RIG-I
- Interferon-induced helicase C domain-containing protein 1
- Nuclear protein localization protein 4 homolog
- Ubiquitin recognition factor in ER-associated degradation protein 1
- FAS-associated factor 1
- E3 ubiquitin/ISG15 ligase TRIM25
- UBX domain-containing protein 7
- UBX domain-containing protein 1
- FAS-associated factor 2
- Transitional endoplasmic reticulum ATPase
Sequence:
MGSLLSSDSSKSAPASATPRTLERSGDSELPITSFDCSVCLEVLHQPVRTRCGHVFCRSCIATSIKNNNKWTCPYCRAYLPSEGVPATDIAKRMKSEYQNCAECGTLVCLSDMRAHIRTCEKYIDKYGPLLELGDTTARCVCPFCQRELDEDCLLDHCIIHHRSERRPVFCPLCHSRPDESPSTFNGSLIRHLQVSHTLFYDDFIDFDIIEEAIIRRVLDRSLLEYVNQSNTT
Protein: Proline transporter 1 (AtPROT1) (P92961)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Proline transporter that mediates proline and glycine betaine transport. May be involved in long-distance transport of proline and required for phloem loading, retrieval of proline leaking from the phloem, or in xylem-to-phloem transfer. When expressed in a heterologous system (yeast), imports D- and L-proline, glycine betaine and GABA across the plasma membrane. Has the same affinity for D- and L-proline.
Subcellular location: Cell membrane {ECO:0000305|PubMed:15618414}; Multi-pass membrane protein {ECO:0000305|PubMed:15618414}. Note=Plasma membrane.
Interaction partners:
- Delta-1-pyrroline-5-carboxylate synthase B
- Proline dehydrogenase 2, mitochondrial
- Proline dehydrogenase 1, mitochondrial
Sequence:
MTATEAKNRKINVGDGDDVVDIEIPDTAHQISSDSWFQVAFVLTTGINSAYVLGYSGTIMVPLGWIGGVVGLLIATAISLYANTLIAKLHEFGGRRHIRYRDLAGFIYGRKAYHLTWGLQYVNLFMINCGFIILAGSALKAVYVLFRDDHTMKLPHFIAIAGLICAIFAIGIPHLSALGVWLGVSTFLSLIYIVVAIVLSVRDGVKTPSRDYEIQGSSLSKLFTITGAAANLVFAFNTGMLPEIQATVRQPVVKNMMKALYFQFTAGVLPMYAVTFIGYWAYGSSTSTYLLNSVNGPLWVKALANVSAILQSVISLHIFASPTYEYMDTKYGIKGNPFAIKNLLFRIMARGGYIAVSTLISALLPFLGDFMSLTGAVSTFPLTFILANHMYYKAKNNKLNAMQKLWHWLNVVFFSLMSVAAAIAAVRLIAVDSKNFHVFADL
Protein: Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (Dwarfin-A) (Dwf-A) (Mothers-against-DPP-related 1) (Mad-related protein 1) (mMad1) (SMAD family member 1) (SMAD 1) (Smad1) (P70340)
Organism: Mus musculus (Mouse)
Function: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25755279}. Nucleus {ECO:0000269|PubMed:25755279, ECO:0000269|PubMed:34995814}. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane (By similarity). Exported from the nucleus to the cytoplasm when dephosphorylated PubMed:25755279. {ECO:0000250|UniProtKB:Q15797, ECO:0000269|PubMed:25755279}.
Interaction partners:
- Mothers against decapentaplegic homolog 4
- E3 ubiquitin-protein ligase SMURF1
- Bone morphogenetic protein receptor type-1A
- Mothers against decapentaplegic homolog 9
- Mothers against decapentaplegic homolog 6
- Mothers against decapentaplegic homolog 5
- Activin receptor type-1
- Bone morphogenetic protein receptor type-1B
- Bone morphogenetic protein receptor type-2
- Signal transducer and activator of transcription 3
Sequence:
MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGGSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMAQDGSQPMDTNMMAPPLPAEISRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Protein: ARM repeat superfamily protein (F4IHU8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Periodic tryptophan protein 2
- Bystin
- Nucleolar-like protein
- Protein NUCLEOLAR COMPLEX ASSOCIATED 4
- Expressed protein family protein)
- At1g42440/F7F22_7
- Probable cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG6
- KRR1 small subunit processome component
- Serine/threonine-protein kinase RIO2
- AT5g04600/T32M21_200
Sequence:
MELLCDDIGTSMCLTPSEPDLPVSEDFGEYMRSRLSQSKRPDHEHLCAVIEELSKTLAEDNHRRTPVAYFACTCRSLDSLFSAHAEPPVDVVQPHIVILSLVFPKVSAGVLKRDGLALRLVLNVLRLKSATPECLISGLKCLVHLLTTVESIMVNEGSDSYNILLNFVTHSDGKVRKLASSCLRDVLQKSHGTKAWQSVSGAITEMFQNYLDLAHKSEVGSTEGARGAKQVLYILSTLKECLALMSKKHIATLIEGFKVLMILRDPYITRPVIDSLNAVCLNPTSEVPVEALLEVLSLAAGLFSGHETSADAMTFTARLLKVGMTRSFTLNRDLCVVKLPSVFNGLNDIIASEHEEAIFAATDALKSLIFSCIDESLIREGVNEIRNSNLNVRKPSPTVIEKLCATVESLLDYKYHAVWDMAFQVVSAMFDKLGEHSAYFMRNTLQGLSDMQDLPDEGFPYRKQLHECVGSALGAMGPETFLSIVRLNLEANDLSEVKVWLFPILKQYTVGGRLSFFTEAIFSMVETMSHKAQKLKLQGLPVASRSVDSLVYSLWALLPSFCNYPVDTVESFADLGRILCGVLQTQAETHGIICASLNILIQQNKEVVEGKEVPTNDASPAMQRATARYDSQHAAANLKVLRLCAPKLLDVLSRIFHECSKDDGGSLQSAIGNLASIAEKKTVSKLLFKTLQELLEATKTAIAQDESPVSGMDVDNTADKNSSSNLRARLFDLLVSLLPGLDGQEVDTIFSSLKPAMQDSKGLIQKKAYKVLSVILKSSDGFVSKNLEELLVLMHNICHVSAKRHKLDCLYFLLAHASRTDDLKERKDIVSSFLPEVILALKEVNKKTRNRAYDVLVQIGHAYADEENGGDNEKLHGYFDMVVGCLAGEKPQMISAAVKGVARLTYEFSDLISSAYNLLPSTFLLLQRKNKEITKANLGLLKVLVAKSPVEGLHANLKSMVEGLLKWPEGTKNLFKAKVRLLLEMLIKKCGTEAVKSVMPEEHMKLLTNIRKIKERKEKKYAAGSDISKSQHSKDTSSKVSRWNDTKIFSDVYADSEDSDGDDMDAESHGRSKASSLLKSKASALRSKKSRNQSHLEVDESDDEPLDLMDQHKTRLALRSSELRKRKADSDEEAEFDVEGRLVIREGERSKRKELSDADSDAKSSKGSRFSGNSSKKNQKRMKTSESGYAYTGKEYASKKASGDLKKKDKLEPYAYWPLDRKMMSRRPEQRAVAVRGMSSVVKMAKKMEGKSAAEALATTKFKKFKRSGQKKSAGKKKNK
Protein: Schlafen family member 9 (EC 3.1.-.-) (Schlafen-9) (B1ARD6)
Organism: Mus musculus (Mouse)
Function: Endoribonuclease that cleaves tRNAs and rRNAs.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q68D06}.
Interaction partners:
- Interferon-induced, double-stranded RNA-activated protein kinase
Sequence:
METYLSLVVKRSYPDLIIYAGEVTLGEKVRNKKDSKKRKLEKTRITQAACALLNSGGGVIVIQMANQSEQPERMGQDLETSLRNLIPSLDLQAFFETKQQEDKFYIFVKSWSSSPEDDSTKPRICSLGTSLYCRSLTSKVAMDSRDAFYFLKKKKAYIKCSPTDDRAPPAKIPRTMSQKSLESNPAFEIFQSKKLEYGQRLLFSESTSIEFKQFDTENAQKYMKDIIPEYISAFANTQGGYLFIGVDDKSIILGCPKDNVDPDSLKIVANEAISKLPVFHFCSSKDKNKVSYETRVIDVFQEGNLYGYLCVIKVEPFCCAVFSEAPISWMVDKEKGVYTLNTEEWVRMMVDVGPEAASNDLSRDFECQLSLSDSPPHCRPVYSKKGLEHKVDLQQRLFQVSPDCLKYTPESLWSELCSQHERLEDLVKQQIRSFSCGLLILSRSWAVDLNLEEKQEVICDALLIAQNSPPILYTILGEQDEQGQDYCTRTAFTLKQKLVNTGGYTGRVCVMTKVLCLSSQNNNKTSGGSVSPIDYPSSYNLANIQEMQGLLQALVIVLLNFRSFLSDQLGCEVLNLLTAQQYEILSKSLRKTRELFVHGLPGSGKTIIAMKIMEKIRNTFHCETDRILYICENQPLRDFIQAKNICQAVTRKTFMNYKFKTERFQHIIIDEAQNFRTEDGNWYEKAKGITRGMKNCPGILWIFLDYFQTSHLQESGLPDFSLQYPKEELTQVVRNADKIAEFLQQELQKIRDNPPCSIPQESLNILHEFKWSQGVSGTYEITYLTLEKMVSYITDKCDVFLSKGYSPQDIAVLFSTDREKKAYEHMFLREMRKRRRASHMNDESVCHSNMFDSIRRFSGLERSIVFGINPIATEQPISHNLLLCLASRAMKHLYILYLSTPEGQSSMVAC
Protein: GH02216p (Virus-induced RNA 1, isoform C) (Virus-induced RNA 1, isoform H) (Q8SXD5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKLLFGLLMTVLALSGVFTLPARNDPQDDAEVIKVPSRPQPESDFHNFRGVIDTGSGYPFLQPNPSSFNVGIFDSFDDLFRRLRTRLWPVIGRDSGEEGASPTGDSDDSSDGSGAGFPFGVRPLIPLDSKNANTTSTIKVVNGHKVEINETVYGDSNSVFKVRLVNVRPLESGEEVAQGVHTSGGDFQPALEPSTSAPPKKFEEFDEEDDDDRREPLEKQPQDNEVRDIDEPKV
Protein: Calcium homeostasis modulator protein 3 (J3QMI4)
Organism: Mus musculus (Mouse)
Function: Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Subcellular location: Basolateral cell membrane {ECO:0000269|PubMed:30804437, ECO:0000305|PubMed:29681531}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the basolateral membrane of epithelial cells including taste cells. {ECO:0000269|PubMed:30804437}.
Interaction partners:
- Calcium homeostasis modulator protein 1
Sequence:
MDRFRMLFQHLQSSSESVMNGICLLLAAVTVKIYSSLDFNCPCLERYNALYGLGLLLTPPLALFLCGLLVNRQSVLMVEEWRRPAGHRRKDLGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSNSVDPEKFLDFANMTPRQVQLFLAKVPCKEDELVKNSPARKAVSRYLRCLSQAIGWSITLLVIVVAFLARCLRPCFDQTVFLQRRYWSNYMDLEQKLFDETCCEHARDFAHRCVLHFFANMQSELRALGLRRDPAGGIPESQESSEPPELREDRDSGNGKAHLRAISSREQVDQLLSTWYSSKPPLDLAASPRRWGPGLNHRAPIAAPGTKLCHQLNV
Protein: Diuretic hormone 44, isoform A (Diuretic hormone 44, isoform C) (FI22022p1) (Q9VH98)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Diuretic hormone receptor
- Diuretic hormone receptor
- Leucokinin
- Protein hugin
- Diuretic hormone class 2
- Short neuropeptide F
- Neuropeptide SIFamide
- Neuropeptide F
- Diuretic hormone 31 receptor, isoform C
- Protein PDF
Sequence:
MMKATAWFCPVLLTLLCATRLVCTAQRGAVGAGGAAGGSGAAAGGAEVGGSGRTNGYPLDYPDGTRNSQDDFLLAKRNKPSLSIVNPLDVLRQRLLLEIARRQMKENSRQVELNRAILKNVGKRVVLRGGGGGGGSGAGGLAPKVSRRYRQQWPVERELERERQRERERERDAVREEQLDRQQLLPWKHFPSQLWSYGWALSPYKESSQLQFADSQQSASTGPQSQALPKQLQLLSYAKKPLDVAGMSLARHRVSGNEANETNHENDDGNGASKNPARYVDDGDNEGEDSYNDVGTEGVGLGLGMGVGLGLERFEVLEDKPNWANEEPNELVVVNANDRVPWSFPYRFHKSQHNVN
Protein: mRNA stability protein mug134 (Initiation of G zero protein 1) (P79058)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}. Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Serine/threonine-protein kinase ppk18
- Protein phosphatase PP2A regulatory subunit B
- Serine/threonine-protein kinase tor2
- Serine/threonine-protein kinase gad8
- Serine/threonine-protein kinase cek1
Sequence:
MVRTRKWMLSTTIIAMSSSNSEQKVDVAKLSPEEQKLFRLYGRLPQRKDLLVQKLQQGRKYFDSGDYALNKAGKASDSGITCIGKEIPSPDTIPHRVVSAGSPNKEPSLHTKRPSESSPSGASSRRESVTRHDLESNEN
Protein: Myelin basic protein (E7F0U0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Myelin membrane {ECO:0000256|ARBA:ARBA00004392}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004392}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004392}.
Interaction partners:
Sequence:
MATASTSGQNPFGLGRKKKAPGVLDQISRFFGGDKKRKGKGSFRGHLSSSPQRPHHSSTRRRGDVNPVVHFFRSFVSSPRPKSRGESRSRSPPKRWSTIF
Protein: Uncharacterized protein (Q388H7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVVSQIGVRTADDSKYEAHEKKLMEDIARQNKNPFECSADFLFGAISVMYRDYLYASGTMLLMWTWWGAYPTYSRLRHKNIMRFRRRRQWEFRRWFFYTRHIPKWDEKYLQAVELPSPYVGPGPVFTPVSPSMIVPSHGSHRSEALMTPLTGTRAEDDNFLVKVNHTAAASFAGGGLSKMETGIAAGVAAINGSLQQSLQTRRILSRNDVDVGKLHEEVAQLIKASRGVVVLKETHNTRHSVPLGREIWWVSLEEARRRWEWWFWASILVAARVLQDLLDMPEMPDFVQ
Protein: Neurotensin/neuromedin N [Cleaved into: Large neuromedin N (NmN-125); Neuromedin N (NN) (NmN); Neurotensin (NT); Tail peptide] (Q9D3P9)
Organism: Mus musculus (Mouse)
Function: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle (By similarity).
Subcellular location: Secreted {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Note=Packaged within secretory vesicles. {ECO:0000250}.
Interaction partners:
- Neurotensin receptor type 2
- Neurotensin receptor type 1
- Sortilin
- Neurolysin, mitochondrial
- Protachykinin-1
- Somatostatin
- Cholecystokinin
- Pro-thyrotropin-releasing hormone
- Gastrin-releasing peptide
- Appetite-regulating hormone
Sequence:
MRGMNLQLVCLTLLAFSSWSLCSDSEEDVRALEADLLTNMHTSKISKASPPSWKMTLLNVCSLINNVNSPAEEAGDMHDDDLVGKRKLPLVLDGFSLEAMLTIFQLQKICRSRAFQHWEIIQEDILDNVNDKNEKEEVIKRKIPYILKRQLYENKPRRPYILKRGSYYY
Protein: Glutathione reductase (GRase) (PfGR) (EC 1.8.1.7) (O15770)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Maintains high levels of reduced glutathione in the cytosol.
Subcellular location: [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:21203490}.; SUBCELLULAR LOCATION: [Isoform 2]: Plastid, apicoplast {ECO:0000269|PubMed:21203490}.
Interaction partners:
- Glutathione peroxidase
- 1-cys peroxiredoxin
- Glutathione S-transferase
- Glutathione synthetase
- 2-oxoglutarate dehydrogenase E1 component
- Bifunctional dihydrofolate reductase-thymidylate synthase
- Pyruvate dehydrogenase E1 component subunit beta
- 3-methyl-2-oxobutanoate dehydrogenase
- Glutaredoxin-1
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
Sequence:
MYKHRYFHFFFFFFFFLVSTKIIRSFTFLNNNTNLSNPVYFKKKANMVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDILENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRILIKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIENTISSDEFFNIKESKKIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADVVEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLNLEKLNVETNNNYIVVDENQRTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEETYLNKKENVTEDIFYNVQLTPVAINAGRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYESKFTNLFFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNATKKDFDETIPIHPTAAEEFLTLQPWMK
Protein: Phosphoinositide phospholipase C (EC 3.1.4.11) (A0A8I6AGE0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAGPGCPLQGLTEDEDVQAMLRGSKLLKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAASQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMSQRERLDHWIHSYLHRADSDQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHSNNERLEGAEIEAFLRRLLKRPELEEIFRRYSGEDRVLSASELLEFLEDQGEDGATLACAQKLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALNVAHTCVFQDMGQPLAHYFISSSHNTYLTDSQIGGTSSTEAYIRAFTQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVIQAVRDHAFTLSPYPVILSLENHCGLEQQIVMARHLRNILGDMLVTQALDSQNPEELPSPEQLKCRVLVKGKKLPAARNEDGRILSDREDEDEDEEEAEEALETAEQRKRAKQISPELSALVVYCCATRLRTLEPSPGPPQPCKIGSLSERKARKFTREAGTSFVRHNTQQLTRVYPLGLRMTSANYNPQEMWNSGCQLVALNFQTPGYEMDLNTGRFLINGQCGYVLKPAYLRQLNTTFDPECPGPPRTTLTVQVLTAQQLPKLNVEKPNSIVDPLVRVEIYGVPEDCAHKETDYVLNNGFNPCWEQTLQFQLRAPELVLVRFVVEDYDTTSPNDFVGQFTLPLNSLKQGYRHIHLLSKDGASLSPATLFVHIRIENS
Protein: Relaxin-3 (Insulin-like peptide INSL7) (Insulin-like peptide 7) (Prorelaxin H3) [Cleaved into: Relaxin-3 B chain; Relaxin-3 A chain] (Q8WXF3)
Organism: Homo sapiens (Human)
Function: May play a role in neuropeptide signaling processes. Ligand for LGR7, RXFP3 and RXFP4.
Subcellular location: Secreted.
Interaction partners:
- Relaxin-3 receptor 1
- Relaxin-3 receptor 2
- Relaxin receptor 1
- Insulin-like peptide INSL5
- Prorelaxin H1
- Prorelaxin H2
- Insulin-like 3
- Relaxin receptor 2
- Neuropeptide S
- Insulin-like peptide INSL6
Sequence:
MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAHEAMGDTFPDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDVLAGLSSSCCKWGCSKSEISSLC
Protein: Uncharacterized WD repeat-containing protein C126.01c (O94394)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MQTNNPSYFFRSESALQDEKRKEEKSHNPNGNPRNLKAKILNIELDRTTPKKKQFPRLFVCEASHICKLYDLEINKTCKTYKGHSGPVTCCQIESLRKDGKVRHIYTGSWDHTIKKWNVSTGECVETLIGHTDYVKCLLLLEEEGLLLSGSTDASLIVWDVSSQPSRLLYKLTGHSRGIECITRQPNTDIFWTCGSESSIRCWHITKVGGSQLEEEGFWGHQSNVYCLLFDPQDSEALWTASADKTVREWSLYQGIHEETRMEHPDVCTDVLTLADGNIATACRDEEIRVWDTTTGNVKDIYSGHYESVTKILQWKSYLISSSLDQTIRVWDLEYSADNNEADDHPSLGPPSTKLTAEELAELEELMND
Protein: External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial (EC 1.6.5.9) (External alternative NADH dehydrogenase NDB1) (NADH:ubiquinone reductase (non-electrogenic) NDB1) (Q1JPL4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). Calcium-dependent NAD(P)H dehydrogenase. Binds calcium ions.
Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Peroxisome.
Interaction partners:
- Ubiquinol oxidase 1c, mitochondrial
- Ubiquinol oxidase 1b, mitochondrial
- Ubiquinol oxidase 1a, mitochondrial
- Ca-dependent solute carrier-like protein
- Ubiquinol oxidase 3, mitochondrial
Sequence:
MTLLSSLGRASRSAPLASKLLLLGTLSGGSIVAYADANEEANKKEEHKKKKVVVLGTGWAGISFLKDLDITSYDVQVVSPQNYFAFTPLLPSVTCGTVEARSIVESVRNITKKKNGEIELWEADCFKIDHVNQKVHCRPVFKDDPEASQEFSLGYDYLIVAVGAQVNTFGTPGVLENCHFLKEVEDAQRIRRGVIDCFEKAILPGLTEEQRRRKLHFVIVGGGPTGVEFAAELHDFIIEDITKIYPSVKELVKITLIQSGDHILNTFDERISSFAEQKFTRDGIDVQTGMRVMSVTDKDITVKVKSSGELVSIPHGLILWSTGVGTRPVISDFMEQVGQGGRRAVATNEWLQVTGCENVYAVGDCASIAQRKILGDIANIFKAADADNSGTLTMEELEGVVDDIIVRYPQVELYLKSKHMRHINDLLADSEGNARKEVDIEAFKLALSEADSQMKTLPATAQVAAQQGAYLAKCFNRMEQCKELPEGPKRFRTGGHHQFRPFQYKHFGQFAPLGGDQAAAELPGDWVSAGKSAQWLWYSVYASKQVSWRTRALVVSDWTRRYIFGRDSSRI
Protein: Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45) (Osteoregulin) (Q8K4L6)
Organism: Mus musculus (Mouse)
Function: Regulates renal phosphate and uric acid excretion. Regulates bone mineralization by osteoblasts and cartilage mineralization by chondrocytes. Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage. Increases dental pulp stem cell proliferation (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12421822, ECO:0000269|PubMed:18597632, ECO:0000269|PubMed:26051469}. Secreted {ECO:0000250|UniProtKB:Q9NQ76}.
Interaction partners:
- Dentin matrix acidic phosphoprotein 1
- Phosphate-regulating neutral endopeptidase PHEX
- Integrin-binding sialoprotein
- Fibroblast growth factor 23
- Osteopontin
- Sclerostin
- Secreted frizzled-related sequence protein 4
- Enamelin
- Parathyroid hormone
- Amelotin
Sequence:
MTPEGLMKMQAVSVGLLLFSMTWAAPMPNEDRSSCGNQDSIHKDLAASVYPDPTVDEGTEDGQGALLHPPGQDRYGAALLRNITQPVKSLVTGAELRREGNQEKRPQSVLSVIPADVNDAKVSLKDIKNQESYLLTQSSPVKSKHTKHTRQTRRSTHYLTHLPQIKKTPSDLEGSGSPDLLVRGDNDVPPFSGDGQHFMHIPGKGGAGSGPESSTSRPLSGSSKAEVIDPHMSGLGSNEIPGREGHGGSAYATRDKAAQGAGSAGGSLVGGSNEITGSTNFRELPGKEGNRINAGSQNAHQGKVEFHYPQVASREKVKGGVEHAGRAGYNEIPKSSKGSSSKDAEESKGNQLTLTASQRFPGKGKSQGPALPSHSLSNEVKSEENHYVFHGQNNLTPNKGMSQRRGSWPSRRPNSHRRASTRQRDSSESSSSGSSSESHGD