wanglab/gogpt-training-data huggingface dataset:
Protein: Cytochrome c1, heme protein, mitochondrial (EC 7.1.1.8) (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1) (Q9D0M3)
Organism: Mus musculus (Mouse)
Function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. Cytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:34616041, ECO:0000269|PubMed:38575788}; Single-pass membrane protein {ECO:0000269|PubMed:34616041}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
- Cytochrome c oxidase subunit 5B, mitochondrial
- Cytochrome b-c1 complex subunit 7
- Cytochrome b-c1 complex subunit 8
- Cytochrome c oxidase subunit 5A, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Cytochrome b-c1 complex subunit 9
Sequence:
MAAAAASLRRTVLGPRGVGLPGASAPGLLGGARSRQLPLRTPQAVSLSSKSGPSRGRKVMLSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNDDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYTEVLEYDDGTPATMSQVAKDVATFLRWASEPEHDHRKRMGLKMLLMMGLLLPLTYAMKRHKWSVLKSRKLAYRPPK
Protein: PHD finger protein 11 (H0Y4X7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XRPGPRGCSAPAARRPGPRRRRSSFPPLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY
Protein: RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf-1) (A0A0R4IN14)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
Sequence:
MEQLQGAWRTVTNGLLTKDSVFESSYVSPVIKSPAPCQSRSSDDSKTSRTIRVFLPNQQRTVVNVRPGMTLHSCLIKALKVRGLQPECCAVFSLHPGQRSKKSRMEWSTDSTSLIGEELLVEVLDHVPLTTHNFVRKTFLKLAFCDICQKFLLNGFRCQRCGYKFHEHCSTKVPTMCVDWTNIRQLLLFPTPGESGAPSLPSLTSRRMRESLTRIPSSSVHRYSNPHVSNYTSPYPPSGAALTQRLRSTSTPNVTMLSTTVPVDSSLIELDTSPSSWCQQFSLKRRDAIRVHSSAGSSPNQSPTGWNQASAHIPASALNPQEKVKIRPRDKRDSSYYWEIEANEVVLLSRIGSGSFGTVHKGKWHGDVAVKVLKVTNPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKGNLAIVTQWCEGSSLYKHLHVLETNFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKARWSGSQQVEQPSGSILWMAPEVIRMQDNNPYSFQSDVYSYGIVLFELMTGELPYSQIGNRDQIIFMVGRGYLSPDLSKLYKRCPKAMKRLVADCIKKSKDERPLFPQILSSIELLQHSLPKINRSASEPSLHRASQSEDISSCTLTSMKLPVF
Protein: Nicotinic acetylcholine receptor Dalpha5 subunit (Q8T5F5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MKNAQLKLTEVDDDELWLAVRLAHCSSNISSSSSTRTTSSNQRHNQQLTTLQPRSLSTKHHSNIASEQHNSQQQEPASKDEDVANHGRSNDQQTHLQQLDSSNMLSPKTAAAATAAGDEATTQQPTNIRLCARKRQRLRRRRKRKPATPNETDIKKQQQLSMPPFKTRKSTDTYSTPAAITSCPTATYMQCRASDNEFSIPISRHDRVSTATFAWVLHVLQVLLVSLQQWQLHVQQRSVLLFRRIAASTIAFISYLGSFAAQLRSSSSSSSNSSNSGNSSSTQILNGLNKHSWIFLLIYLNLSAKVCLAGYHEKRLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQVCPANVTRSITTAARNPI
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Q38DM7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004637}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004637}. Mitochondrion intermembrane space {ECO:0000256|ARBA:ARBA00004569}.
Interaction partners:
- NADH dehydrogenase subunit NI8M
- NADH-ubiquinone oxidoreductase complex I subunit
- Uncharacterized protein
- NB-ARC domain-containing protein
- Adrenodoxin reductase, putative
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase complex I subunit
- Peptidyl-prolyl cis-trans isomerase
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- Uncharacterized protein
Sequence:
MTEYLKDIGRTKPGDPMPPINLGPYDNPLLWNMLDPFGADRGHQRRPMSVSRDFMELHNVPIIFRDQCVHRWVPFHRCLKNLKPVTWGTANCHEFEEAWMICRAYETYRNQLLKTKFMELTKDYTAEDKKFFPSLLHLSVPTYMNSFYWTMAASQRLSGWDERDPANPMTWREPNRALMRAEFSPTNWEQGNLTNATGHKLITDDLVFDMVPGFPLPEDKRPETLY
Protein: Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (Cytoplasmic tRNA adenylyltransferase 1) (Thiolation of uridine in tRNA protein 1) (O76365)
Organism: Caenorhabditis elegans
Function: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03053}.
Interaction partners:
- Cytoplasmic tRNA 2-thiolation protein 2
- Elongator complex protein 1
- Elongator complex protein 3
- DNA replication licensing factor mcm-5
- Adenylyltransferase and sulfurtransferase MOCS3
- Elongator complex protein 2
- Putative rRNA methyltransferase
- cysteine desulfurase
- WD repeat-containing protein 74
- RNA helicase
Sequence:
MEKRRGPPPCQSGSGCSNPAKIRKAKDGAQLCGPCFSRNFEDDVHEAIVNNKLFKRGERVAIGASGGKDSTVLAYVMKTLNDRHDYGLDLQLLSIDEGIKGYRDDSLLAVEKNRVEYGLPLTILSYRDLYGWTMDDIVAKIGKKNNCTFCGVFRRQALDRGAFKIGATKLVTGHNADDMAETLLMNVLRGDIARLERCTNIVTGEEGDLPRAKPLKYCFERDIVMYARTNQLEYFYTECIYAPNAYRGYARKYVRDLEKVHPRAILDLIRSGEKVSVKKEVEMPTLKICERCGYMTSQKLCKACLLIEGLNTGNTDLGVRKSKKSKKVTVEADELNKEGGCGSGGGGGGCGCAGAEDAAENEETRQRLKDLQF
Protein: Target of rapamycin complex subunit wat1 (TORC subunit wat1) (WD repeat-containing protein pop3) (O74184)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: component of both TORC1 and TORC2, which regulate multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression. TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2. TORC2 is required for cell survival under various stress conditions. TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Positively regulates amino acid uptake through the control of expression of amino acid permeases. May play a role in mRNA maturation as a coupling protein between splicing and synthesis and/or stabilization.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Serine/threonine-protein kinase tor1
- Target of rapamycin complex 1 subunit mip1
- Target of rapamycin complex 2 subunit sin1
- Serine/threonine-protein kinase tor2
- Target of rapamycin complex 2 subunit ste20
- Target of rapamycin complex 2 subunit bit61
- Uncharacterized protein C63.05
- Serine/threonine-protein kinase sck1
- Serine/threonine-protein kinase atg1
- eIF-2-alpha kinase GCN2
Sequence:
MSVQYPPQHSVLLVSSGYDHTIRFWEALSGICSRTIQHADSQVNRLCISPDKKFLAAAGNPHVRLYDINTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQRNYDHKSPVNDLLIHPNQGELLSCDQSGRVRAWDLGENSCTHELIPEEDVPMSSITVGSDGSMLIAGNNKGNCYVWRMLNHQGASLLQPVVKFQAHQRYITRCVLSPDVKHLATCSADATVNIWSTEDMSFMLERRLQGHQRWVWDCAFSADSTYLVTASSDHVARLWELSSGETIRQYSGHHKAAVCVALNDYQI
Protein: Geranyltranstransferase (Q8XJE0)
Organism: Clostridium perfringens (strain 13 / Type A)
Interaction partners:
- Isoprenyl transferase
- Exodeoxyribonuclease 7 small subunit
- Exodeoxyribonuclease 7 large subunit
- Probable di-trans,poly-cis-decaprenylcistransferase
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
- Heptaprenyl diphosphate synthase
- Gx transporter family protein
- Probable hemolysin
- 1-deoxy-D-xylulose-5-phosphate synthase
- Bifunctional protein FolD
Sequence:
MKKRKTLEDTAMNINSLKEEVDQSLKAYFNKDREYNKVLYDSMAYSINVGGKRIRPILMLLSYYIYKSDYKKILTPAMAIEMIHTYSLIHDDLPCMDNDDLRRGKPTNHKVFGEAIAVLAGDALLNEAMKILVDYSLEEGKSALKATKIIADAAGSDGMIGGQIVDIINEDKEEISLKELDYMHLKKTGELIKASIMSGAVLAEASEGDIKKLEGFGYKLGLAFQIKDDILDVVGNAKDLGKNVHKDQESNKNNYITIFGLEECKKKCVNITEECIEILSSIKGNTEPLKVLTMKLLERKF
Protein: Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60) (P30101)
Organism: Homo sapiens (Human)
Function: Disulfide isomerase which catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds. Associates with calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Association with calcitriol does not affect its enzymatic activity.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:23826168}. Endoplasmic reticulum lumen {ECO:0000250|UniProtKB:P11598}. Melanosome {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). {ECO:0000269|PubMed:12643545}.
Interaction partners:
- Calreticulin
- Tapasin
- Beta-2-microglobulin
- Endoplasmic reticulum chaperone BiP
- Calnexin
- HLA class I histocompatibility antigen, A alpha chain
- Endoplasmin
- Antigen peptide transporter 1
- HLA class I histocompatibility antigen, B alpha chain
- Endoplasmic reticulum resident protein 27
Sequence:
MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
Protein: CD27 molecule (F7FDI3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP
Protein: O-acyltransferase (Q6DHG2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|PIRNR:PIRNR000439}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|PIRNR:PIRNR000439}.
Interaction partners:
Sequence:
MIDKDDFGPVTRNRRRATITSTRSESVKLRNGASATAAAADSGLKSGHKARESLAKNLQLNEENKRKCDRYDRMSCHKLQESMLSSASSFKNYRGILNWCVVMLVLSNARLFLENLLRYGILVDPIQVVSLFLKDPYSWPAACLVIVCNAFILVALYTERKLAMGSISEKVGLLIYIFNLTIILCFPMVVVLKLPSITPVGGAFALGIYTILFLKLYSYKDVNKWCRERTQAKARSLSRSLSCPSPPSTSSSMQSYVSYPGNLSLRDIYYFVFAPTLCYELNFPRSESIRMGFLLRRLFEMLLLTQLLVGLTQQWMVPIIRSSMKPLQEMDYTRMTERLLRLAVPNHLLWLIFFYSFFYSSMNFMAELLRFGDREFYRDWWNSETITYFWQNWNIPVHKWCLRHFYKPLLRRGAGKLLSQSAVFFASAFFHEYLVSVPLRMFRLWAFMGMMAQIPLAWLVSRFLRGNYGNAAVWLSLIIGQPIAVLMYVHDYYVTNHQDDLTINEDL
Protein: Insulin-like growth factor-I (F1DFL1)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU000406}.
Interaction partners:
Sequence:
GAELVDALQFVCGDRGFYFSRPTGYGSSSRRLHHKGIVDECCFQSCDLRRLEMYCAPIKPPKSARS
Protein: Rho-GAP domain-containing protein (Q965S4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEHNDFRVVTSSSVYRKGSTTTAGAAAAGPKSNKLSYTLGEVCSTNVTLDVNVGTGWTRIRLKEVPKFIVHAFNIISKHGMDTDGIFRKEGNSVRLNRAEVQAIYKGQSDIPNDYSVIDVCTMVKRFLRDLKPPLLDSEECRARLLKKACQARISDSFLMTRDEMADIFYLEDRTIEQQTPLLSDVHASTLGYVMRQLYRIAAHSDQHKMSIENLAIVLVGSVFGDGIHDPRKTSQIRRGSKEDILAQKRQDMSVNTAAVKLLITNANLIGVRRDPYVTSNAMLRSSSAMPRCMSSGYETSSSDADCLSSNIAQTAAAALHQRGEAGAGGPSTSLAIHRRDSEAVHKIVTSRKKGELLESKKKRSASFLPSFRDLKHRLSNMKRAKSPSPERLMTGHTAAAIEPPLTADTLDLYTDHRKKVARNESNTMSTGSTASGRQSRSHQNRRGNTNAAPRSGGSGKNTISKMFEHEQQQVVPSSGGALRRLSANDQNTDAMRFAKQRVSNEQMSVAEFLISEHQRERECKIQKRNTVILGEKSRSSKLTNRRHTAPINNNRLRRNRPNTVGAGLPHRKDGGSSLEEKENQADCEETTDDTLDATNNVDHSEWLLEQKALEARSRRAGRKNKAATTTTTAMRNISTESMMVLNGSMMAVESTTDVLKADPLVAMDVLKEESSPHTTTTPKNTPKVVLRKDLNDVKRMKQFCDMATSPMVMDTPTKLSHENGHAWVGTKQVISVTRTPSLSRRQSRARLSYSKATESPLDMPSSDVRRDSGSLMSPLLKHVTITNNSPPSQVITSSPRTNHLTPKSHTLSPLAVKIERSTPLPPPPIPPHSPPHLTPQRTSKVSLDAVSEMKRISISGGHARRPPTPPSHPRVSNPFSPKLPIRSVTIDNGFELPATASTAAAAAGVPDETQFKLPQLPMPPKKKVSPLLARQATHSSKSTTLSVPNRANLRETKSIDETPTALRSAPPAAQGSSSNQLSPRSSTDYFEFGKYTNALRSATDEFALPTRKTSVESRPSVAILRSNNCGLVRSRVNHFQEIEHSQRVETSMSGRLSAMSQSSLRSSNDTHQSSSDRFSDVSDLRNAAFSESTSDSALSTPTATPTTSRVSTNDAAAAAAAAQHF
Protein: Sirohydrochlorin ferrochelatase, chloroplastic (AtSirB) (EC 4.99.1.4) (Q84JH7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Chelates iron to the siroheme precursor. Catalyzes the last step of the siroheme biosynthesis. Unlike its counterparts in bacteria, contains an [Fe-S] cluster which is not involved directly in the enzymatic reaction, but may play regulatory role in iron, sulfur and tetrapyrrole metabolism. The [Fe-S] cluster is required for normal plant growth.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:15545265}.
Interaction partners:
- S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase, chloroplastic
- Polynucleotide 5'-hydroxyl-kinase NOL9
- tRNA-5-taurinomethyluridine 2-sulfurtransferase
- At2g29670/T27A16.23
- At1g07280/F22G5_32
- Tetratricopeptide repeat
- Assimilatory sulfite reductase
- Ferredoxin--nitrite reductase, chloroplastic
- Protoporphyrinogen oxidase 2, chloroplastic/mitochondrial
- Endoglucanase 22
Sequence:
MTTQSQFLVNLSYGGLASQSNLRANNRVSPSSCQITRTNRSWALPVSFKVEKFQLQRGRRRRGSPCFGESEGLVKNGIGDADGIIIVDHGSRRRESNLMLEEFVKMFKEKTGYPIVEPAHMELAEPSIKDAFSLCVQQGAKRVVVSPFFLFPGRHWHTDIPSLTADAAKEFSGISYLITAPLGPHNLLLDVVNDRIQHCLSHVEGDADECLVCAGTNKCKLYNSS
Protein: Peroxidase (EC 1.11.1.7) (Q8RVP7)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU362060}.
Interaction partners:
Sequence:
MASSFGVLFVVGVWMMMGSGSYAQLSTNFYSKSCPKVLSTVELVVETAVSKEQRLGASLLRLFFHDCFVNGCDGSVLLDDTSSFTGEQTATPNNGSLRGFEVVDEIKAKVEKVCPGVVSCADILAIAARDSVVILGGPDWDVKLGRRDSKTASFSDANSGVLPLGSANLSQLISLFQAQGLSTKDMVALSGAHTIGKARCLVFRNRIYNDTIIDTSFAKTRRSSCPRTRGSGDNNLAPLDLATPNSFDSKYFENLLNKKGLLHSDQELFNGGSTDSLVKTYSSNVKKFYSDFIAAMIKMGDIKPLTGSNGEIRKNCGKPN
Protein: Flagellar FliJ protein (Chemotaxis CheF protein) (P20487)
Organism: Bacillus subtilis (strain 168)
Function: Flagellar protein that affects chemotactic events.
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Interaction partners:
- Flagellum-specific ATP synthase
- Probable flagellar assembly protein FliH
- Probable flagellar hook-length control protein
- FlaA locus uncharacterized protein YlxG
- Flagellar protein FliL
- FlaA locus 22.9 kDa protein
- Flagellar M-ring protein
- Flagellar biosynthetic protein FliZ
- Flagellar motor switch protein FliM
- Flagellar motor switch protein FliG
Sequence:
MAYQFRFQKLLELKENEKDQSLSEYQQSVSEFENVAEKLYENMSKKELLEQNKEKKLKSGMSVQEMRHYQQFVSNLDNTIYHYQKLVIMKRNQMNQKQEILTEKNIEVKKFEKMREKQFKMFALEDKAAEMKEMDDISIKQFMIQGH
Protein: Citrate synthase 4, mitochondrial (EC 2.3.3.16) (P20115)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:14671022}.
Interaction partners:
- Aconitate hydratase 2, mitochondrial
- Aconitate hydratase 1
- Aconitate hydratase 3, mitochondrial
- Malate synthase
- UPF0235 protein At5g63440
- ATP-citrate synthase beta chain protein 1
- Malate dehydrogenase 1, mitochondrial
- Isocitrate dehydrogenase, chloroplastic/mitochondrial
- ATP-citrate synthase beta chain protein 2
- Cytosolic isocitrate dehydrogenase
Sequence:
MVFFRSVSAFTRLRSRVQGQQSSLSNSVRWIQMQSSTDLDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVIGGMRGMTGLLWETSLLDPEEGIRFRGLSIPECQKVLPTAQSGAEPLPEGLLWLLLTGKVPSKEQVEALSKDLANRAAVPDYVYNAIDALPSTAHPMTQFASGVMALQVQSEFQKAYENGIHKSKFWEPTYEDCLNLIARVPVVAAYVYRRMYKNGDSIPSDKSLDYGANFSHMLGFDDEKVKELMRLYITIHSDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSVVEECGEDISKEQLKEYVWKTLNSGKVIPGYGHGVLRNTDPRYVCQREFALKHLPDDPLFQLVSKLYEVVPPVLTELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRSLGICSQLIWDRALGLALERPKSVTMDWLEAHCKKASSA
Protein: Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137) (Q9DC50)
Organism: Mus musculus (Mouse)
Function: Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate.
Subcellular location: Peroxisome {ECO:0000305}.
Interaction partners:
- Trifunctional enzyme subunit beta, mitochondrial
Sequence:
MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHDMIQLMNTAHL
Protein: CCN family member 1 (Cellular communication network factor 1) (Protein CYR61) (F1QL10)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Angiomotin-like 2a
- non-specific serine/threonine protein kinase
- TEA domain family member 1a.
- CCN family member 2
Sequence:
MFAWAVIVIFIAHFNMVSSSCPAVCSCAPDAPQCPPGVGLQRDACGCCLVCARQLNEDCSRSEPCDHSKGLECNYGASHGATRGICRAKSEGRPCEYSSRIYQNGESFQPNCKHQCTCMDGAVGCVPLCPQELSLPALGCANPRLVKVPGRCCEEWVCDDEQQGGKLIESANKMPGNKEVGGDSEKELTNKNELISVIMNTKLKSLPAFRSHQMEKCIVQTTGWSQCSRSCGTGISTRITNNNAECKLMKESRICEVRPCSQSPHTSLKKGKKCNRTKKSVTPVKFSYAGCSSLKKYRPRFCGSCVDGRCCSPQNTRTIRVKFRCQDGETFNKNVMMIESCKCTKHCPHASEAGFPFYRLYNDIHKFTD
Protein: Short-chain dehydrogenase/reductase family protein (Q54I22)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MILFEDVVKSFIDNMNDYLMIIVSFFGSLLLLLIGPFLNLINITKNKTKFGTPKTIVITGSNSGMGRGIAIAYAKPGVTLGLIGRNIERLQDVKNECIKKGANVIIESIDITDKEKMNNWLLSFDKKYTVDILIANAAVSELMLPKELNFNDRTYELTNINVMGMLNTALPLIENFEKRGNGQIVLVSSLTSYLNFVLPTYCGSKAFVTSFGLTLRNRLKDSGVGVSIVAPGFVDTPMSDSLKQDSLPFSVTPNQAATIILDGISKNKAFIAFSLPTLLFTYFVNIIPPNLKDSWNYISTFFFKHPEFNPPNTSNSNSNNTDSSSSKFKKN
Protein: RNA-binding protein (Q389I1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEYSSDAVLNGYALLVWCAPSVKEEGDTFLRAFFLRRFQGTVAASPASIVFATPNGSHKTTFWGADGEGGAEPPDRGSEALVFFREREGVKIVLSGIVQRILHEKEPHSGVELLRGYVFLGTDRLLVEGVFHPTSCAVGAGGTEVSGRANTSGSDDSLWRRRVCTDSCSQSLMGWGQPRAEVVGMGRDETVDYNRVTDSYLGGGGDFAATPSQGCDNKNHSDPQCNSYHGKSREHNRGGRIVLRVTFVCLLGRCKGLHEGGHGGCHSTGVSTHVVFKLLRGTCFPRGIIMFPPRLLGCTDGVMGGDGAWGVDAVVEVEDAEAANSVVDSFDGSLLELVKPGPNSDEVEFRFRLFVREDRPGVEQKLSIPFNTESELSITPSNLLQMGGSFRCEKYSVEPADTAANGRWNAAVVRANGIADNLVGLGSIQHFSRDLAPGHQGMNYGHDAGLSRSPERGYDSVQRSRNRSRGRSRSRSRSRSRRRARRRDRSRSQHRSRVRSRSRSRSGRRGRRRAHGRSRSRNRSRGRSRIRTRGRKRSRSSSRGSWYSYSSASNSDRSRSRSPSLSRSRTRSSGKARRSENVGDDEISKKCALTHHRYQ
Protein: Proteasome subunit beta type-3 (20S proteasome subunit beta-3) (Q9NDA1)
Organism: Trypanosoma brucei brucei
Function: Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MSILTYSGGSCLAMAGKECFVVISDNRLGEQLKTISMEVPKLHVINDGIVMGLTGLRTDQQTFAQKVNFRTEMYKLREERDINGKAFAALVSSMLYEARFGPWFVEPVIGTIDRKTGEVYLCATDLIGAPCEPEDYVCAGTCAESLHGMCEALWRPGLEPEELFEVAAQAMLSACDRDSLSGYGAVAAIVTKDKLVTRLIKGRKD
Protein: Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) (P19836)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:639816}. Membrane {ECO:0000269|PubMed:24275660, ECO:0000269|PubMed:639816}; Peripheral membrane protein {ECO:0000269|PubMed:639816}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P49585}; Peripheral membrane protein {ECO:0000269|PubMed:639816}. Nucleus {ECO:0000269|PubMed:8185307}. Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000269|PubMed:24275660}.
Interaction partners:
- Cholinephosphotransferase 1
- Choline/ethanolaminephosphotransferase 1
- Choline kinase alpha
- Choline/ethanolamine kinase
- Choline-phosphate cytidylyltransferase B
- Phosphoethanolamine/phosphocholine phosphatase
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase 8
Sequence:
MDAQSSAKVNSRKRRKEVPGPNGATEEDGIPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTHERSPSPSFRWPFSGKTSPSSSPASLSRCKAVTCDISEDEED
Protein: Uncharacterized protein (Q581D3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MCLSKIFSPVDQSLKVLVEVMTRLAGQEVVKGTRKRGRSKECGTDEEAHFVIRINGRVTQVPSAAPSLNLRQLLGQAGVLLQDITDEETPILLLPCPNTGNVTVHPNHNYRLVKFVGEHVCPAGDFFPANDHEIDAITFTAEGNKLHKKRVFQSKKLADSTLGSLMVFLQSNKISYARDFLMLKPEEVEIYKGKATAAMMRHCIKGVELESSDEEVEESEVCYEGKEDEED