wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein (Q54M12)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MKYILFFFIIGLLYVKSQDFPVINPNYVSYVSYNNYLEGFTFSSKEYNFDSQKITVREFEDVIIYSDWTSETSSINFNSTWYNYPTNSEMGSSFDFLKPENYLFVRNETIDRGFSCSVFENSIDDTITTPIQAISKFDLTGEIDITLIKSLGGQSCFNQVVGNVDSAKFTCEHKDGKTKCSILYTESSTDSSSSSTDSSSSSSTDSSSSSSTDSSSSSSSTDSSSSSSSTDSSSSSSSSSTDSSSPSSTDSSSPSSTDSSSPSSTDSQTPTPNEENTINKLNMKLLSGLKENNPITTECTFDGILEKEIVETFGSYENIVNSDVNITVEINAKITTYISLPNNIPVRIIFKGDVGFDGKSKPVDVNIGFVGWTLLEALPSSFAKPDCENDKCPDLPIDNGSFEFPKDLKLEDATTLSLNNTEFSAVFEEVVDSSLNSVNNWYHDQSLQMDAFIIEQTKGETYSRISNNGLNSFNVDSFTLSCNNNKIKTSDLIDETVIEILTNASNLQWTFVTRTTRRSVAVDQWNTAIDNNKSVNLYTFARGWQFLFRHGLNSLTMSIPVAVEIITTSSNEESTTTTTTKKEIDIFLFDIISIPTKIKDFNEESCIPTLPTTYDSMITINNLKYGYTQQYQEIYSSIDTTSTTIGRYHSSDLYSVYNKNQSVTQWGSTNNDHKCKTFENVKNQYHYSSTLANQLSDISTLPKTFSKLTDTIHQWSSTNSTHAIVHTWSTNGESASPINITISLINQSESLTTLIQTIDFYSYSTSTLTNVNIPTNCTIVKIENDDDDDDDDDEKDKDEEDEIKTDNLEQQVNDHDDDDDDVPYGPKSFDKEFTLQTIDTKKHPKVLKTFTINIQVTNTDKDGIITKSNNVIWKYSKDKLAESYKYTNKVDGVELCFTDSSMNIANISLNGSKSDGPFSNAYYNKYFFGDNSIARLFTDQSYLNQFTISTTYTNIDGLNLTTLSKESDNSNVYYFPAGWSFETFDTTNTDLSTPLLITKVNNGSTETWRIIKYDNTVDSDLYSKCQPPKKGGIHVNISKNGIIAVVVIVVVVIIGVGAIVFIVIKKRGGLGKKMPAHILLDEQEQNRTYEN
Protein: PHD finger protein 11A (PHD finger protein 11) (PHD finger protein 11-like) (Q8BVM9)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- PHD finger protein 11-like
- Histone-lysine N-methyltransferase SETDB2
Sequence:
MAQEKPGCSNPVPNGDCPIIEKMEKRTCALCPEGHEWSQIYFSPSANIVAHENCLLYSSGLVECEAPDLPNTVRNFDVKSVKKEIGRGRRLKCSFCKNKGATMGYDLQSCTKNYHLSCAMEDHAILQVDEDHGTYKLFCQKHAPEGQEPTQRDAAVKAPFLKKCQEAGLLNVLLEYILEKMDLIHGRLLNETASESDYEGIETLLFGCGLFGDTLRKFQEVINSKACEWEERQRLMKQQLEALADLQQNLCSFQENGDLDCSSSTSGSLLPPEDHQVRCQESPEVQAGSGDSL
Protein: ER membrane protein complex subunit 3 (Q9P787)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- ER membrane protein complex subunit 1
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 4
- TPR repeat protein oca3
- UPF0620 protein C83.10
- ER membrane protein complex subunit 5
- Ubiquitin-conjugating enzyme E2-18 kDa
- Nuclear cap-binding protein subunit 2
Sequence:
MQKLLLDPALRNWVLLPIMFVMILIGILRHNATILLQSSPKKLSKEEIREQRLLQRAYALRACSNSLLPESIEARKCFLIESLKSGKYLKPVDPNAPKAANPLMDDKTLEGLMESMKGNMLMVVPQTIIMTWINEFFSGFILLKLPFPLTLRFKSIFQSGVATQDLDVQWVSSISWYFLNLFGLKSVYALLLGENNAASNATNEMGMAGFSSAAATAQLIQPGQDISKMMLSEAENVQILKNESLLVDVEKRLLAQFA
Protein: Transcription activator MSS11 (Multicopy suppressor of STA genes protein 11) (Q03825)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcription factor that regulates pseudohyphal differentiation, invasive growth, floculation, adhesion and starch metabolism in response to nutrient availability.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Protein STE12
- Flocculation protein FLO1
- Morphogenetic regulator of filamentous growth protein 1
- Protein MSN1
- Flocculation protein FLO11
- AP-2 complex subunit mu
- Ty transcription activator TEC1
- Flocculation suppression protein
Sequence:
MDNTTNINTNERSSNTDFSSAPNIKGLNSHTQLQFDADSRVFVSDVMAKNSKQLLYAHIYNYLIKNNYWNSAAKFLSEADLPLSRINGSASGGKTSLNASLKQGLMDIASKGDIVSEDGLLPSKMLMDANDTFLLEWWEIFQSLFNGDLESGYQQDHNPLRERIIPILPANSKSNMPSHFSNLPPNVIPPTQNSFPVSEESFRPNGDGSNFNLNDPTNRNVSERFLSRTSGVYDKQNSANFAPDTAINSDIAGQQYATINLHKHFNDLQSPAQPQQSSQQQIQQPQHQPQHQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQTPYPIVNPQMVPHIPSENSHSTGLMPSVPPTNQQFNAQTQSSMFSDQQRFFQYQLHHQNQGQAPSFQQSQSGRFDDMNAMKMFFQQQALQQNSLQQNLGNQNYQSNTRNNTAEETTPTNDNNANGNSLLQEHIRARFNKMKTIPQQMKNQSTVANPVVSDITSQQQYMHMMMQRMAANQQLQNSAFPPDTNRIAPANNTMPLQPGNMGSPVIENPGMRQTNPSGQNPMINMQPLYQNVSSAMHAFAPQQQFHLPQHYKTNTSVPQNDSTSVFPLPNNNNNNNNNNNNNNNNNSNNSNNNNNNNNNNNNSNNTPTVSQPSSKCTSSSSTTPNITTTIQPKRKQRVGKTKTKESRKVAAAQKVMKSKKLEQNGDSAATNFINVTPKDSGGKGTVKVQNSNSQQQLNGSFSMDTETFDIFNIGDFSPDLMDS
Protein: Large ribosomal subunit protein mL50 (39S ribosomal protein L50, mitochondrial) (Q9V3E3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Large ribosomal subunit protein bL32m
Sequence:
MAAILRKTLILAGSLHRSFASAAKAAKAKPVKTSTISAVGESIAAKGFLRPHKPYSPPADAAERIRTVAASLQLKSDQLGNLSEKFEFLNACFQELQHGVPNSQVHELRTVSDVIAFYQTAVDTTVPFDALKRIELPENLHIQYEYVRFHPETDTKFDGKTAFPKSSTLVTGLKYRGKYEGHEAKRSWP
Protein: Early boundary activity protein 2 (Q9VQD6)
Organism: Drosophila melanogaster (Fruit fly)
Function: The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba2 can act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression.
Subcellular location: Nucleus {ECO:0000269|PubMed:23240086, ECO:0000269|PubMed:25561495}.
Interaction partners:
- Early boundary activity protein 3
- Early boundary activity protein 1
- Zinc finger protein ZIPIC
- Boundary element associated factor
Sequence:
MAGGFRPYDQDSCPNLTNSEAPEFSMSVVCKTEPHYFHPQTAILPSVQYSHPYHHYLSQFAPNFVPYYYRLLSRPIMKQEEMDIENYINYEVAAQQTMMRQRTLKPLGQLQIQMPPPIIVNQPVKPVPVKAVPVRRSSPPKRRVINAQLVAVATASGGIKNIEPRVEPLPRLEESFKQQVAKIQKSQHHYEQLFGRLTSMLKTLNQRYDNDAEDVPAPPSKRPRHMSTSSSESHIPDTASEKDEKDTLVQYPHRVQKEDGSAVYVLGPNGTQITAHQYGEVFWTNAPVATRCLLCVVFSSDELATHTLTGKPSPAFYGRERPPKLQLDQRKVDDIVVCVRNRTGGKERVIRATITTKCADTAKKYKRRAKKAQKVAIKEEY
Protein: Uncharacterized protein (A0A0W0EI05)
Organism: Candida glabrata (Yeast) (Torulopsis glabrata)
Interaction partners:
Sequence:
MVAMHFRKKSNLSNGGEDEHRLSDVKVSKEDAARLKIRTASVNDPILDAVNEAQPFEQAADTFHDNMNRQSYFSTDGGNVLRDVFGQPITTPDISNPTRARDERPLDTIRSFEYAVSGDPSWAQQLETATYGFRPRPDFPLLNPYANNASASQAYNEQAVYQPPVHEVGEKKKKKRGLFGRKKKSKD
Protein: Focal adhesion kinase (Q2TGI0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
TDDYAEIGLLEGEGDYSTPTVRNYELDRALITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETL
Protein: CD33 antigen (Gp67) (Q546G0)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ
Protein: Bacterioferritin (EC 1.16.3.1) (Q72C87)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Ferritin
- Rubredoxin
Sequence:
MTTATDREQRKAKVIEVLNKARAMELYAITQYMNQHYGLDSMDYGELAANVKLIAIDEMRHAEMFAERIKELGGEPTTDPEGAIIKGQEVRIVFPFDADLEDDTIDAYNQFLLVCRECGDSVSMKLFETIIDEEQAHFNYFDNVGGHIRTLGDTYLSKIAGTSASTGPSTKGFLLNKGG
Protein: Uncharacterized protein C3H7.08c (O74383)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSIMRSIMSNRLVRWSREYPELFITWCVMTYTFGVAGYMLGQRGLLVQHEDQVRIPSKNAHPWEDTKSSSGKSDESLDYSYKYYPRGDRSKEPRKAPSAIQYSTFPVKGVSEEVLERFSK
Protein: Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Q9P6P0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Transcription initiation factor TFIID subunit 4
- TATA-box-binding protein
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 7
- SAGA complex/transcription factor TFIID complex subunit Taf10
- SAGA complex/transcription factor TFIID complex subunit Taf6
- Transcription initiation factor TFIID subunit 2
- SAGA complex/transcription factor TFIID complex subunit Taf12
- Putative transcription initiation factor TFIID 111 kDa subunit
- Transcription initiation factor TFIID subunit 14
Sequence:
MEETQIDELYFSLMRIFCSQTLRAAGIDRTKVSLLNSFTDITIRYIRLLSETAMAKAEVGRRSCCDLGDLRLAMEEIGLLNGSEEDVKTLVEWFNGPQVAELRRVSGFVQDSETQVKPKDWLTSLIQKQIRVSGPERFYETVFSASNEEEDVKDS
Protein: Non-classical export protein 2 (Q12207)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in membrane organization. Required for the formation of membrane compartments of CAN1 (MCCs), localization of CAN1 at the MCCs and subsequent invagination of the plasma membrane at the MCCs sites. Involved in eisosome organization and might act as a sensor of sphingolipids that regulates plasma membrane function. Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. It may be an accessory subunit to an essential core component of the non-classical export machinery. Non-classical export pathway functions also as an alternative clearance/detoxification pathway to eliminate damaged material, when the basic repair pathway is not sufficient.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10716729, ECO:0000269|PubMed:12469340, ECO:0000269|PubMed:19064668, ECO:0000269|PubMed:19564405, ECO:0000269|PubMed:20581291}; Multi-pass membrane protein {ECO:0000269|PubMed:10716729, ECO:0000269|PubMed:12469340, ECO:0000269|PubMed:19064668, ECO:0000269|PubMed:19564405, ECO:0000269|PubMed:20581291}. Note=Associates with the ergosterol-rich membrane compartment of CAN1 (MCC). Accumulates in membrane domains at eisosomes.
Interaction partners:
- Sphingolipid long chain base-responsive protein LSP1
- Sphingolipid long chain base-responsive protein PIL1
- Protein SUR7
- Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1
- Uncharacterized protein YMR181C
- Eisosome protein SEG1
- Nitrosoguanidine resistance protein SNG1
- Uncharacterized plasma membrane protein YNL194C
- Serine/threonine-protein kinase PKH1
- SUR7 family protein FMP45
Sequence:
MLALADNILRIINFLFLVISIGLISSLLNTQHRHSSRVNYCMFACAYGIFTDSLYGVFANFIEPLAWPLVLFTLDFLNFVFTFTAGTVLAVGIRAHSCNNSSYVDSNKITQGSGTRCRQAQAAVAFLYFSCAIFLAKTLMSVFNMISNGAFGSGSFSKRRRTGQVGVPTISQV
Protein: Pogo transposable element-derived with ZNF domain a (Uncharacterized protein LOC100535215) (A8E7N7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- PC4 and SFRS1-interacting protein 1a.
Sequence:
MRNMADSDLYMQCDEDELEPCQSVTESRGQRLNKVTVVPSVINAQISPQPNGASTDQTSAAFGLPNQAVPLASAPAVTLLPNAVQTGGAAGQTIYFSAQPNSGQPLAGSMNLGTYFLNGQPVSFVTAGQTPQLIAPRMVTPGSAQQTAPGKVSTMQMPVALTLNSPSNLQSITPAAPGVNARNVTPSNILPATAPGSIIKVIKFMKYPGAPGSAGQVMSSVAQPSQPMSIQNSITHQTPVSILPAGIAQTLMPQMQILAPAPGTASNALKRTSSSSTFCPRCKAVYQKSLPLRGYFCQCSQELIKSIWSLKSHTKNRLRARSKRPPRDTPASSASSKTSQKDVTSCELPEGAPNPRSGDFDEQGRMIMLVEDFFYGQHPGRPADVRYPWEHISMKCHLCSKKLIGNIEMMNHMKHHMERDCRTGEVDCHTVCQHCYRNFSTPFGLQCHVEAVHIQAESSKVCKICECLFESEPLFLNHMKHVHKPGEMPYVCKVCDFRSSFYKDVMNHFTEHHKDTCILLCVYCLKIFRSCGGFQLHYTRHQKKGARNCDKCRLQFCSEKDEWHHKQRFHRTYVKPKQLEGLVPGTRIIIRAYADNTDNRAQFGEPPVEPCPNTTSTPDQSQNVHSKIVPVKKKPVESMVELMVKFESNFNPKEKKYYCMECNHDIPYFSNHFPTYVSCSLCRYCTCCSRAYANHMISVHVPRKSTKKYITLYKPCPKKGRLSCTKCKFNTTIGDSMAKHLANFPKHQASRSTIQEGFSQGYKRFVFIPTNLLRGGQRLNNTGFLHLQVKQVDRSSSIPLLQPSYTITLPASPARMPPLPIQAQPTEKSKVRPIAPKPALHSLTAAQNKVVLYALCCGVPQAAIHFNKPPEEVHSLLLKRQTVVEPSKGKYFLTPQAADKLIQWVYCQREQQLPISEANLLEFMYNHGSRDFSYDSVVDFFLRHDLGLQAFATSSKLPPLHCQQLERSFSSFLKEQVNSQAFSLSSIGSMDELSVFVDLEKLVDSTSMMSAFKLIGTTEPTIDVVFTALADGNLLSVMLFVKSEPPTLDAHSLSDSVILEARPEGFTNEERLQVWIDKVWSPYVNPSSGGKGLLMMDLYKGHTSNEFLAALNRVNTLPGLVPHGCSRRLQPLEVCMGPVLREFMQASWTELVTKAPQELVGAKPADLAIIIARWLTEVLDVLKAEPKHLFRSFDWILSTNESSEEPAELMRSLTEALLASKLQGDKVEEQKAETSSVVSAESWPSPQSSILALKKIFEKDSDVETFHGFEDSEITDL
Protein: Probable ADP-ribosylation factor GTPase-activating protein AGD9 (ARF GAP AGD9) (Protein ARF-GAP DOMAIN 9) (AtAGD9) (Q9FIQ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: GTPase-activating protein (GAP) for ADP ribosylation factor (ARF).
Interaction partners:
- Coatomer subunit beta-2
- Coatomer subunit beta-1
- Structural molecule
- Coatomer subunit gamma
- Coatomer subunit delta
- Coatomer subunit alpha-2
- Coatomer subunit alpha-1
- ADP-ribosylation factor GTPase-activating protein AGD7
- Probable ADP-ribosylation factor GTPase-activating protein AGD6
- Coatomer subunit beta'-3
Sequence:
MATENLTDKNVVFRKLKSKSENKVCFDCSAKNPTWASVPYGIFLCIDCSAVHRSLGVHISFVRSTNLDSWSPEQLRTMMFGGNNRAQVFFKQHGWNDGGKIEAKYTSRAADMYRQTLAKEVAKAMAEETVLPSLSSVATSQPVESSENGFTSESPKESSLKQEAAVVSSPKASQKVVASTFKKPLVSRKSGKTGGLGARKLTTKSKDNLYEQKPEEPVPVIPAASPTNDTSAAGSSFASRFEYFDDEQSGGQSGTRVLSHVAPPKSSNFFNEFGMDSAFPKKSSSSSSKAQVEETDEARKKFSNAKSISSAQFFGNQNRDADLDSKATLQKFSGSAAISSSDLFGHGPDDSNIDITASDLINRISFQAQQDMSSIANLAEETKNKLGTFASSIFSDLQDRML
Protein: Glucose/ribitol dehydrogenase family protein (Q54D21)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MEPINNIDKVFLVSGTSTGLDYKVAAFTRSKLIVENEIKKYYENNNEKNIDYLNSLLAVQVDITNEESVENGVKETVNKFGHFDVVINNAGYGQWGNVEETSDKEARAIFDVNYFAILNIVRSTTPYLRKQKSGLILNVSSILGHAPKGGISSYVASKYAVTGLTLSLEQELAPFNIKVVLLSPGGFRTDITNKEKFKLVENPIPEYYPNSTPQNSLEAFSDFINTSNGDPNKFANAILKLDLIHQQGNKLPSNIFFGSDALEGSSHFFKSLIDESNQWKELALSTDRS
Protein: Fibronectin type-III domain-containing protein (D3DEL7)
Organism: Caenorhabditis elegans
Subcellular location: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
Interaction partners:
Sequence:
MATSYLTESLAGPTSARGSSYSYSYESHYDNPPEEEYEHFTNDDGVHQMQKVTRVTKVTTTRSVRQVPVQSPYSNIDFDSSGLPTPSPVIDRDPSLEMMARMGGASDHDSEDRSAPPPAPASRFLHEDSGIPSAPGVPDVVDAGIGEVTVVWSAPLQSNGGEVRGYQIEMREFPDGEWESMGVDHLLKDTTCRVTNLTSHEVQFRVSAYGRTGFGPASNPSLPVKIPISETDLATSAGAPLAPGRPTVIAVDGQGVLLEWTPPVADVHSSPPQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGVYEFRVRGKNQDGLGHPSMSSGGVAIRPAAPQRHVPARKVSESVQPPGQPQMVEVGDDVVKLEWAPSVQNARYIVEYREVGDPEWHTANYDPIVQNGIQVEGLHRNSTYEFCVISIVDNIASQPSETSDIIHLRPTCNTSALRPAPNILEAPEFLEVDGDKITICWLPAQSQLPVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNASGCSQPSPPSDFVHIEPSTNRFSSDTMESPHLGHHDVVKYVEAERFGAVPLLQEEMVRESPPLPERDDSPPPLRRANNNVQWRDPSLKEVIEYLSSADKDKQLNASGYLQHLTYTDNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLSFGKENDANKLAVMEADGVRLIAEVLRTTHDASVKEEAAAALWNLSSADMLKPVILESATEILSQQVIAPVLAVGTSDPTRHFGSTLFKNSTGVLRNVSAASQQARRRLRDIPNLIEALVHFLTHAIQKSQVDSPTVENAVCLLRNLSYRIQEVVDPNYDPAAAHSSSSKNMKHVASPKPEKKKKDKEKKKDKNPKNIVTGPSVLWQPHVVKLYLKLLQDSSNIETLEASAGAIQNLAACQFPPSAEVRAAVRVEKGLPVLVELIRLPEDFVVCAVATALRNLAIDPRNRELIGKYALRDFLDKLPEPGSPRRSAISDQTIGAVLGILFEIVRSSAAYTKDVHELKGTDKLRALSRSYPTYSHRVCKYASQVLYVMWQHKELHDGFKRSGLKEADFYSGTARRGDSSTLARPISSQGRERPSMHQLDETLSSGGGYGTMESNNRAGTLRPASATSQTIQRRYDQVPRDGPVYSSVQKPSPRGGGGGGNIDDSWV
Protein: AB hydrolase superfamily protein C4A8.06c (EC 3.-.-.-) (O14158)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MLKKEQLTVESINDGISKTFSQAFRFLAHHELRKNRTFMLDLGVSILKKFLIDSRDYKVEVVQDFCSRSLTDEFKFKFTSQPIDSKSESDSASYIRNYLGPEGIKQFGGSNWWLYRKSPLKSWWIERRHHIRHNLKCDKVIFYVHGGAHYLSTVRTNAYHIQRHTAALGARTFAPDLRLAPQFPFPCSLHDVLSSYLYLLKSTKPENIIFMGDSSGAGLIVASLVLIRDSKLPLPAGVVYDSPWVDLTHSLPSVVADDAADYIPSEGFHHRASRYWPITNLDSFSTISEKELLNYSKKQELTNFIENSIRKKIQTIKNLIPVLQEMDKEHARIDFDNVDSRLDPNILTTFPFQVQFYTSNANLKHPLISPIFTENLGGLPPSLVLGGSGERLRDEIVYIAHKMNTDVYNGKRTKVRLEMYDDCCHVVTALPFVKEAGIMVRRAANFAYWCLKQHDSSFVSPNKHLDGNPSHANEDMVRLRISRNGEERLMEPKDEIQCLNLPKSALGTIQVKALIRWIDVELILLSKDTKKPARYFAEFKHADLNGYLVKPKEYTMEGENPPLSALVANCKISPEKKQ
Protein: Interleukin 10 receptor subunit alpha (G3V830)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Interleukin-10
- Interleukin 10 receptor subunit beta
- Tyrosine-protein kinase
- Tyrosine-protein kinase
- Signal transducer and activator of transcription 3
- Interleukin-6
- Interleukin-13
- Interferon gamma
- Tyrosine-protein kinase JAK2
- Interleukin-5
Sequence:
MLPRLLPFLVSISSLSLGFRAHGTELPSPSSVWFEARFFQHILRWMSIPNQSESTYYEVALKKYGTSVWKDIHICSKAQTLSCDLTTSTLDLYHSSGYRARVRAVDNSQYSNWTITETRFTVDEVILTVDSVTLKVSNGFIYGTIHPPRPNLVPVGDEYEQIFTHHRIYRVCIRKFSEQKNITKTVEQENFTLEVPKGMRKFCVKVMPHVESRINKAEWSEEQCLHVTTEHYFTVTNLSIFFLSILILCGALVCLVLLWYIRHPGKLPAVLVFEKPPDFLLANPRCPETLDDIHILDLEAFPKVSPELKDSDLHGSTDSGFGSGKPSLQTEESQFFLLDSHAQIQETLGKEGSSELQDTCGDNTDSGICLQESSLHSSMGPPWKQQFGYTHQDQDDSDLVQNSPGHPKHTQDGSALGHGCLLEPEVPEEKDQVMVTFQGYQKQTRWKEEAAEPLDGEIPLAEAFDPELGVRLQGDSAWPPVALATGYLKQESQGMASAPPGTPSRQWNQLAEECSLLGVVSCEDLSIESLGFAHELVPLDCGAASSGLLDSLGTNLVTLPLISSLQIEE
Protein: Receptor expression-enhancing protein 2 (Q8VCD6)
Organism: Mus musculus (Mouse)
Function: Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity).
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Atlastin-1
- Reticulon-2
- Rab3 GTPase-activating protein non-catalytic subunit
- Spastin
Sequence:
MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIILSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDALPLQGPDGRLQPGPVGLLDTIEDLGDEPALSLRSSTSQPDPRTETSEDDLGDKAPKRTKPIKKVPRAEPPASKTLKTRPKKKSSGGGDSA
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) (GCN5-like protein 1) (Protein RT14) (Protein acetyltransferase BLOC1S1) (EC 2.3.1.-) (P78537)
Organism: Homo sapiens (Human)
Function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
Subcellular location: Mitochondrion intermembrane space {ECO:0000269|PubMed:22309213}. Mitochondrion matrix {ECO:0000269|PubMed:22309213}. Cytoplasm, cytosol {ECO:0000269|PubMed:22309213}. Lysosome membrane {ECO:0000305|PubMed:25898167}.
Interaction partners:
- BLOC-1-related complex subunit 5
- Dysbindin
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- KxDL motif-containing protein 1
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- Biogenesis of lysosome-related organelles complex 1 subunit 3
- BLOC-1-related complex subunit 6
- SNARE-associated protein Snapin
- BLOC-1-related complex subunit 7
- Biogenesis of lysosome-related organelles complex 1 subunit 4
Sequence:
MAPGSRGERSSFRSRRGPGVPSPQPDVTMLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKGQLQSAPS
Protein: BEN domain-containing protein 5 (Q8C6D4)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional repressor.
Interaction partners:
- Cytosolic carboxypeptidase 6
Sequence:
MYAFVRFLEDNVCYALPVSCVRDFSPRSRLDFDNQKVYAVYRGPEELGAEPESPPRAPRDWGALLLHKAQILALAEDKSDLENSVMQKKIKIPKLSLSHVEDDGEVKDYGEEDLQLRHIKRPEGRKPSEAAHKSIEAVVARLERQNGLSLGHSTCPEEVFVEASPGTEDMDSLEDAVVPRALYEELLRNYQQQQEEMRHLQQELERTRRQLVQQAKKLKEYGALVSEMKELRDLNRRLQDVLLLRLGSGPAIDLEKVKSECLEPEPELRSTFSEEANTSSYYPAPAPVMDKYILDNGKVHLGSGIWVDEEKWHQLQVTQGDSKYTKNLAVMIWGTDVLKNRSVTGVATKKKKDAIPKPPLSPHKLSIVRECLYDRIAQETVDETEIAQRLSKVNKYICEKIMDINKSCKNEERREAKYNLQ
Protein: Popeye domain-containing protein 2 (Popeye protein 2) (Q9ES82)
Organism: Mus musculus (Mouse)
Function: Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q9HBU9}.
Interaction partners:
- Potassium channel subfamily K member 2
Sequence:
MSANGSSVAQLLWQPPVCRSWKPDVEGAVYHLANCFLLMGFMAGSGVYGCFYLFGILGPGYLCCVLWGWFDACGLDIVLWNVLLTVACLLQLAQLVYRVRVNTLPEEFNLLYRTLCLPLQVPLQVYKEIVHCCHEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLHPSEEGTFQVTLTAETECSYISWPRKNLYLLLNRERYISRLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLSPSASDGEPESEKDDEEALEAAVSPAQARPICIVPTPPCSAPPATTNFPVPLPRARMPRMPRPDSGNLASRRPLQNSSQVMSRSQAPLAPIHTPEL
Protein: Beta carbonic anhydrase 6, mitochondrial (AtbCA6) (AtbetaCA6) (EC 4.2.1.1) (Beta carbonate dehydratase 6) (Q9C6F5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Reversible hydration of carbon dioxide.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:17407539}.
Interaction partners:
- Cyanate hydratase
- Gibberellin-regulated protein 9
- Mediator of RNA polymerase II transcription subunit 15a
- Tubulin-folding cofactor D
Sequence:
MAFTLGGRARRLVSATSVHQNGCLHKLQQIGSDRFQLGEAKAIRLLPRRTNMVQELGIREEFMDLNRETETSYDFLDEMRHRFLKFKRQKYLPEIEKFKALAIAQSPKVMVIGCADSRVCPSYVLGFQPGEAFTIRNVANLVTPVQNGPTETNSALEFAVTTLQVENIIVMGHSNCGGIAALMSHQNHQGQHSSLVERWVMNGKAAKLRTQLASSHLSFDEQCRNCEKESIKDSVMNLITYSWIRDRVKRGEVKIHGCYYNLSDCSLEKWRLSSDKTNYGFYISDREIWS
Protein: rRNA-processing protein EBP2 (EBNA1-binding protein homolog) (P36049)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the processing of the 27S pre-rRNA. Probably involved in the step of the processing of the 27 SA precursor into the 27 SB intermediate.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:10849420, ECO:0000269|PubMed:10947841}.
Interaction partners:
- Ribosome assembly factor MRT4
- Ribosome biogenesis protein ERB1
- Nucleolar complex-associated protein 3
- Ribosome biogenesis protein NSA2
- 60S ribosomal subunit assembly/export protein LOC1
- Ribosome biogenesis protein NSA1
- Ribosome biogenesis protein YTM1
- Ribosome biogenesis protein RLP24
- Nucleolar GTP-binding protein 1
- Pumilio homology domain family member 6
Sequence:
MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVTASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKHMSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKEESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQEHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFAEMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETLEKIKSLKNKRKHNEIDHSEFNVGVEEEVEGKRFDRGRPNGKRAAKNAKYGQGGMKRFKRKNDATSSADVSGFSSRKMKGKTNRPGKSRRARRF
Protein: Protein PsbN (P0C419)
Organism: Oryza sativa subsp. indica (Rice)
Function: May play a role in photosystem I and II biogenesis.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00293}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00293}.
Interaction partners:
- Photosystem II reaction center protein L
- Cytochrome b559 subunit beta
- Cytochrome b6-f complex subunit 4
- Photosystem II CP47 reaction center protein
- Cytochrome b6
- Photosystem II reaction center protein J
- 33 kDa subunit of oxygen evolving system of photosystem II
- Photosystem II reaction center protein T
- Photosystem II reaction center protein I
- Cytochrome b6-f complex subunit 5
Sequence:
METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD