wanglab/gogpt-training-data huggingface dataset:
Protein: NFAT nuclear factor, isoform C (NFAT nuclear factor, isoform H) (E1JJP5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRFTYNQYKHYESGYRIPSKMHNLSHNNNNNSNNNNNGGGHTNNNNNGNNSGHHYAHHNNSNNGGNNNTNFQAYQHHYKSNFGMRMTMSTNSTMSARIHRKGFRIPSKRQPGKGLPGKLHTITRTGPGKMVPGKRIPQRPHPPPCDNSNDSGLGFDQHTELRSSAGAGGVTDPAANGGSGSNSGQRSSLLVNSALTNTVAAAAAAAAAAVASNTLQQHQQHHQQQQQQQQQQQQQQQQQQQQQQQQQHSPQQHLIRAIPVSRFISARNVTRVANKRQPTTPLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGYDKVAVLQVFIGTDIGRVAPHMFYQACKVAGKNSTQCNEKKVDGTMVIEIDFKPETDMTITCDCVGILKERNVDVEHRFPEHLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPPGVPEICKKSLNSCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKEYLHQTHLICTVPPYLHQNILKPVQVQVSIVSSGKKSEPHTFTYTAKGQYTTLAAASTLSNTIHAQDVSGFMDTTSASNASGSSGWSAAGGSGNNTSTGDNVEAKHEIDSGMMPPPITTQIPMGVRRSSLPSVTPMITDQQLVHLNAVAASAEALKTELDDSNSHSPLTGESTPDSPNAALQYHRFARKPSLDTIMYDQSNSLPGFPTVVAPATAAAVAAAVDIDPTAVAVAVELAVKNEIVKHVVQQHQQMQEQMHEQQQQQQQQQQQQQQQQQQQPQQQQQQQVHKFIDELTKSTSVVSSNGTTEPALFTTSAVIDHALTDILQAKVGIAPPNVVLERSLSLSSTNSSSSMSGSESSPNSSPLTQDIILNSEPAAALAGAAALGGPAPVDVTGGLSTDIIMNPAVSPSTILCSANGAATAVVPNILAPHQVTMANSILNDIAMQPEPTQQDAAVAALALSNIMMSPPTAASGVGVGDTLPPTPATMQPEVAATATSTAVSNMIIKAAADFITTQEQEQHHYHHHGRIHSHSPQAAVGVSGNPAETASDPLVDLLLNHSNTPETAAAAAAAVAVEAANFQSMNHSHHSHHGHHGHSHGHGHSRVTGHVSGHVTSHHRGHHLPVVPPTPQESLIVALASENALQKSVATAAVTTNGAVMTQQASAPNTAGSILPAAVGAVAAAAAVAVQPPIPQELTTMSDQDLISYINPSTFDQL
Protein: Hexosyltransferase (EC 2.4.1.-) (E7F6G2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000256|ARBA:ARBA00004447, ECO:0000256|RuleBase:RU364016}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004447, ECO:0000256|RuleBase:RU364016}.
Interaction partners:
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
- Hexosyltransferase
- Hexosyltransferase
- Hexosyltransferase
- Hexosyltransferase
- Hexosyltransferase.
- Hexosyltransferase.
- Hexosyltransferase
- Sulfotransferase
- Carbohydrate sulfotransferase
Sequence:
MVQRDASTLLNCVFLPVLLLRLPVVMLRRGLLAWLSRLGVLLVVVCCCLSLLYVITCSPHADDPMAGQPLPRAGGMALAGGPSRPGGVGGAPVGPAGREGFQALLQEREEQHRQHIASLKKQIAQLKEALQERSEQLKGMQDSLEKSTGKGMGGDVAEDRSHSDLQQFLRSQLSRAEVHTGVRLPSEYAVVPFESFTLQRVYQLEMGLTRHPEEKPVRKDRRDELGEVVESALHALNAPNHGREKTKASKVYTPSDFIEGLARTEKDKGSLYELTFRGEHKHELRRLVLFRPFGPLMKVKSELVETSHMPINIVLPLSQRADKFRQFMHNFREVCVKQDGRVHLTVVYFGKDQMNEVKGTLENTSRELNFRNFTLIQLNEEFSRGRGLDVGARAWKGGNVLLFFCDVDIIFTADFLNTCRLNAQPGKKVFYPVLFSQYNPAVIYGSHDHVPPVDQQLIIKKDTGFWRDFGFGMTCQYRSDFINIGGFDVDIKGWGGEDVHLYRKYLHSNLLVVRAPSRGLFHLWHEKRCADELPPDQYKMCMQSKAMNEASHGQLGMLLFRHEIEAHLRKQKQRSGAKKA
Protein: Calcium-binding protein, putative (Q583R2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPHSMDTTLFSDENRIDRGDSLLFHCVQLSQGGTDSHRYFFGCYFPRWRGFYMDEARELPGPLGYNVTRHFPAFPFDVYLKDDGEHFLTDDFQIGSIFTLGGPLNQRDDGQKRYKVVHCDDSQLRTRTGKTLAFIGNNVSGLLQQTHRVSGEAIDALKRIREAYIFNVGNGIPEVGIKAMGRHFRKVGSDGRRWMSYEGIVRFVKDSRNFNATLSFSDTQRTEEDVNTVATCIYNAFPKNEEECIDYDFFMDYVRGPMSQERKDAVWNIFRRMDYDRDGNLNIIDIQACYNTQDHPTCSVDHLFQSDKMLKGFLTIWDENERCGLVPYAEFLDYYNGVSAVLEDDKVFFDVLNNQWKLL
Protein: HTH-type transcriptional regulator Rv2034 (O53478)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the regulation of lipid metabolism and hypoxic response. Positively regulates transcription of various genes, such as phoP, groEL2 and dosR. Negatively regulates its own transcription. Acts by binding to a specific palindromic sequence motif in promoter regions.
Interaction partners:
- Activator of Hsp90 ATPase homologue 1/2-like C-terminal domain-containing protein
- Mycothiol-dependent maleylpyruvate isomerase metal-binding domain-containing protein
Sequence:
MSTYRSPDRAWQALADGTRRAIVERLAHGPLAVGELARDLPVSRPAVSQHLKVLKTARLVCDRPAGTRRVYQLDPTGLAALRTDLDRFWTRALTGYAQLIDSEGDDT
Protein: Tetraspanin (F8W022)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Cell surface {ECO:0000256|ARBA:ARBA00004241}. Endosome, multivesicular body {ECO:0000256|ARBA:ARBA00004559}. Late endosome membrane {ECO:0000256|ARBA:ARBA00004107}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004107}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004155}. Melanosome {ECO:0000256|ARBA:ARBA00004223}. Membrane {ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
Interaction partners:
Sequence:
MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF
Protein: C-C motif chemokine 16 (Chemokine CC-4) (HCC-4) (Chemokine LEC) (IL-10-inducible chemokine) (LCC-1) (Liver-expressed chemokine) (Lymphocyte and monocyte chemoattractant) (LMC) (Monotactin-1) (MTN-1) (NCC-4) (Small-inducible cytokine A16) (O15467)
Organism: Homo sapiens (Human)
Function: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Subcellular location: Secreted.
Interaction partners:
- C-C chemokine receptor type 1
- C-C motif chemokine 5
- C-C chemokine receptor type 2
- C-C chemokine receptor type 5
- C-C chemokine receptor type 8
- C-X-C chemokine receptor type 5
- C-X-C chemokine receptor type 2
- C-C chemokine receptor type 3
- C-C motif chemokine ligand 4 like 2.
- C-C chemokine receptor type 9
Sequence:
MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ
Protein: Threonylcarbamoyl-AMP synthase (TC-AMP synthase) (EC 2.7.7.87) (L-threonylcarbamoyladenylate synthase) (Q384E0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|PIRNR:PIRNR004930}.
Interaction partners:
Sequence:
MARIIDVSELDYAAHSLTRGGLVALPTETVYGLGGNALDERAVQQIFEVKGRPSTDPLICHVPDIQRAVGLWDSNADPAALEVAKWIGDAIWPGPLTIVFRANSVLPPSVTGNSGYVGVRIPNHPIALQLLQLVNFPVAAPSANTFGHVSPTTAEHVLRDLGERCPSLLVIDGGHSNIGIESTVLKVASATKVEILRRGKVSLADLQQVIWKKFACHITVRDTRSCPGTVDMAMDGPGQLLTHYSPSVLSGMLTPKSTNCEVHQNELDKAVVELPSTPPLTGGVPLNQTVIIDFGGLLQRFQRVCLAYRDLSAEGEVQQACFAVFEALRWSETVSGAGVVLFPLISEWPCKTGDEELLAAVEDRLFRAASGKIANIRFG
Protein: Opticin (Oculoglycan) (Q9UBM4)
Organism: Homo sapiens (Human)
Function: Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:18164633}.
Interaction partners:
- Fibronectin
- Matrilysin
- Collagenase 3
- 72 kDa type IV collagenase
Sequence:
MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT
Protein: Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7) (Q91ZA6)
Organism: Mus musculus (Mouse)
Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR (By similarity).
Interaction partners:
- Insulin receptor substrate 4
- Tyrosine-protein kinase JAK2
- Insulin receptor substrate 2
- Elongin-C
- Insulin receptor substrate 1
- Insulin receptor
- Insulin receptor substrate-3
- Cullin-5
- Suppressor of cytokine signaling 3
- Elongin-B
Sequence:
MAENNSKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESCSESEAIGTVENVEIPLRSQERQLSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSGRHSPGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTVPMSPNSDEWVSADLSERKLRDAQLKRRNTEDDIPCFSHTNGQPCVITANSASCTGGHITGSMMNLVTNNSIEDSDMDSEDEIITLCTSSRKRNKPRWEMEEEILQLEAPPKFHTQIDYVHCLVPDLLQISNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSPMKLYLKEYHYKSKVRLLRIDVPEQQ
Protein: MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (EC 2.7.11.1) (P49071)
Organism: Drosophila melanogaster (Fruit fly)
Function: Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25).
Interaction partners:
- Mitogen-activated protein kinase p38a
- Mitogen-activated protein kinase p38b
- RE23625p
- Protein TIS11
- Extracellular signal-regulated kinase 7
- Cyclic AMP response element-binding protein B
- Heat shock factor protein
- Transportin-1
- UT01525p
- Heat shock protein 23
Sequence:
MLSLQNQRQPKTTPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVLLDSERARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAEETWPEVQEEMTRSLATMRVDYDQMQIKALDKSNNPLLTKRRKKIEEMELYMANATRN
Protein: Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (GP130) (P42704)
Organism: Homo sapiens (Human)
Function: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:19262567, ECO:0000269|PubMed:23822101}. Nucleus {ECO:0000269|PubMed:19262567}. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus outer membrane. Note=Seems to be predominantly mitochondrial.
Interaction partners:
- SRA stem-loop-interacting RNA-binding protein
- Microtubule-associated protein 1S
- Exportin-1
- Translational activator of cytochrome c oxidase 1
- Heme-binding protein 2
- Heme A synthase COX15
- Chromatin remodeling regulator CECR2
- Surfeit locus protein 1
- Protoheme IX farnesyltransferase, mitochondrial
- YTH domain-containing family protein 1
Sequence:
MAALLRSARWLLRAGAAPRLPLSLRLLPGGPGRLHAASYLPAARAGPVAGGLLSPARLYAIAAKEKDIQEESTFSSRKISNQFDWALMRLDLSVRRTGRIPKKLLQKVFNDTCRSGGLGGSHALLLLRSCGSLLPELKLEERTEFAHRIWDTLQKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYCNVGDIEGASKILGFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTVMRDAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCERRYIPDAMNLILLLVTEKLEDVALQILLACPVSKEDGPSVFGSFFLQHCVTMNTPVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGFPIRPHYFWPLLVGRRKEKNVQGIIEILKGMQELGVHPDQETYTDYVIPCFDSVNSARAILQENGCLSDSDMFSQAGLRSEAANGNLDFVLSFLKSNTLPISLQSIRSSLLLGFRRSMNINLWSEITELLYKDGRYCQEPRGPTEAVGYFLYNLIDSMSDSEVQAKEEHLRQYFHQLEKMNVKIPENIYRGIRNLLESYHVPELIKDAHLLVESKNLDFQKTVQLTSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESDMVTGGYAALINLCCRHDKVEDALNLKEEFDRLDSSAVLDTGKYVGLVRVLAKHGKLQDAINILKEMKEKDVLIKDTTALSFFHMLNGAALRGEIETVKQLHEAIVTLGLAEPSTNISFPLVTVHLEKGDLSTALEVAIDCYEKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMVMLYDLFFAFLQTGNYKEAKKIIETPGIRARSARLQWFCDRCVANNQVETLEKLVELTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPREKTLRLLAEILREGNQEVPFDVPELWYEDEKHSLNSSSASTTEPDFQKDILIACRLNQKKGAYDIFLNAKEQNIVFNAETYSNLIKLLMSEDYFTQAMEVKAFAETHIKGFTLNDAANSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVIQALAMKGDVENIEVVQKMLNGLEDSIGLSKMVFINNIALAQIKNNNIDAAIENIENMLTSENKVIEPQYFGLAYLFRKVIEEQLEPAVEKISIMAERLANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRNSRKQGKASTVKSVLELIPELNEKEEAYNSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYASLLKYAGEPVPFIEPPESFEFYAQQLRKLRENSS
Protein: Multidrug resistance protein MdtA (Multidrug transporter MdtA) (P76397)
Organism: Escherichia coli (strain K12)
Function: The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function.
Subcellular location: Cell inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- Multidrug resistance protein MdtB
- Multidrug resistance protein MdtC
- Periplasmic chaperone Spy
- Probable aminoglycoside efflux pump
- Signal transduction histidine-protein kinase BaeS
- Inner membrane protein YebE
- Outer membrane protein TolC
- Probable L,D-transpeptidase YcfS
- Putative multidrug resistance protein MdtD
- Transcriptional regulatory protein BaeR
Sequence:
MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSRSAAPGATKQAQQSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLIALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPEEKATSREYAKKGARS
Protein: HIRA-interacting protein 5, putative (Q38B74)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Paraflagellar rod component, putative
Sequence:
MLRGTRLMLMMQLHSLPTPNPSCYTFHIPSSTYDNFIPDGQTCDVAHMGLAWVHPLSQGIFEQYPQEVASVFIAPRHTSITVHPHVDWNKLEWSISSFIGHYLVFTNACFPAAAEYALLEDDLVIHEDDSEVLQCIKELVREQVRPMVQRDGGDVKLLNFNEKTGVVSLAMLGACRTCPSSQNTLKDGVERLLKHFLPEVKEVVEAKGHAFYEEYGLLFDSEKALREEAARVDAVRRRKISIYTTAPLMPFEALNEPDGDE
Protein: Amino-acid permease 1 (Q92367)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Ribose-phosphate pyrophosphokinase 1
- Uncharacterized protein C56F8.15
- Uncharacterized protein C56F8.13
- Uncharacterized protein C18B11.08c
- Pyridoxal phosphate homeostasis protein
- Uncharacterized protein SPBC713.14c
- Putative uncharacterized transmembrane protein SPBC713.13.
- Uncharacterized protein C887.16
- Ribose-phosphate pyrophosphokinase 2
- Ribose-phosphate pyrophosphokinase 5
Sequence:
MTSFTESKKLDEIESPVPEIIVPSTTNGNGTIESYKEKSVGTSFLDFFRSYKLRPDNEFAEVHNSEDFLKPRHLQMIAIGSCIGTGLFVSTGKSLKNAGPGSLMINFIILSAMILALILSLGEMCCFLPNQSSITMYTGRLLNNNIGFAQSWLYFWIWLTVLPSEISAACEVVDFWTTQHLNPAIWVTIFLAYVVLVNAFGARSYGECEFVSSFLKVVIVIIFFFVAIIINCGAAPKGGYIGAHYWHHPGSFRNGFKGFCSVFISSAYSLSGTENIGTAAGNTSNPQRAIPSAVKKVFYRMGFFYIITIFLITLVVPYDNPDLGNVSPFIIAIKNGGIHVLPHITNAVILVSVLSVGNAAVFAASRNAMALVKQGWAPRFLGRVDQKGRPVISYLCSLAMACIAYVNAAPDGSVVFDWLMSVSGGGAFVIWGLSFIDHIRLRYAMKAQKIPDTVLPYKFPGSVYLSYYGVLINFLALCALVYISIFPVTHEKPSAYGFFVSFLGPSVFIAYLLISPIFVKPTFQSLKDVDLTTGRYDLVNSQMYVAESSTSELSEKDLTKPNLQSNDNKNSEDLESNTPPQKKSALQKVADFLC
Protein: TFG protein (Q05BK6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQMYQQYSNRPAMVHSSRRLHLSSLNSMVFSIQQAIVSRLDLNNLSSSRDMASNQLPRHQLLPFLVSLNNCLLSRHSSTRRAIILHKLTLPKLLSLLIILWLLPLNLEWLQANLGPINQDQVLLHFLEVP
Protein: Small ribosomal subunit protein RACK1 (D6REE5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTLSLDLEIKPSSYGIPWVCANTLSSLILSPRLECSSAISAHCKLCFPGSRHSPASASRVAGTTGACHQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYT
Protein: Early light-induced protein 2, chloroplastic (Q94K66)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably involved in the integration of pigments into the mature light-harvesting pigment-protein complexes. Light-harvesting chlorophyll (LHC) a/b-binding protein required to ensure a high rate of chlorophyll accumulation during deetiolation in continuous high light. Involved in seed germination. May fulfill a photoprotective functions. Prevents excess accumulation of free chlorophyll by inhibiting the entire chlorophyll biosynthesis pathway (e.g. 5-aminolevulinate synthesis and Mg-protoporphyrin IX chelatase activity), and hence prevent photooxidative stress.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:10725357, ECO:0000269|PubMed:16829586}; Multi-pass membrane protein {ECO:0000255}. Note=Associated with both photosystems I and II (By similarity). Coisolates equally with monomeric (mLhcb) and trimeric (tLhcb) populations of the major LHC from photosystem II (PSII) in response to 2 hours light stress. {ECO:0000250}.
Interaction partners:
- Light-harvesting complex-like protein OHP1, chloroplastic
- Chlorophyll a-b binding protein 7, chloroplastic
- WD repeat-containing protein RUP2
- Transcription factor HY5
- Photosystem II 22 kDa protein, chloroplastic
- L-ascorbate peroxidase 2, cytosolic
- Probable folate-biopterin transporter 7
- Chlorophyll a-b binding protein 2.4, chloroplastic
- Early light-induced protein 1
- Cysteine/Histidine-rich C1 domain family protein
Sequence:
MATASFNMQSVFAAPSGVLTTRNIRNTNQLFFKRIAPVGVRCMAQGDPIKEDPSVPSTSTSATPPQMPQSPPPPVSKPKVSTKFGDLLAFSGPAPERINGRLAMVGFVAAIAMELSKGENVFAQISDGGVGWFLGTTALLTLASMVPLFKGIRAEAKSKGFMTSDAELWNGRFAMLGLVALAFTEYVTGGTLV
Protein: CLOCK-interacting pacemaker (CLOCK-interacting circadian protein) (Q9C0C6)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in an animal model showed that CIPC is not critially required for basic circadian clock.
Subcellular location: Nucleus {ECO:0000269|PubMed:26657846}. Cytoplasm, cytosol {ECO:0000269|PubMed:26657846}. Note=Predominantly localizes to the nucleus, where it co-localizes with CLOCK. At the G1/S boundary, partially translocated to the cytosol. {ECO:0000250|UniProtKB:Q8R0W1, ECO:0000269|PubMed:26657846}.
Interaction partners:
- Circadian locomoter output cycles protein kaput
- Basic helix-loop-helix ARNT-like protein 2
- Neuronal PAS domain-containing protein 2
- Basic helix-loop-helix ARNT-like protein 1
Sequence:
MERKNPSRESPRRLSAKVGKGTEMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLFIEATKSRAPQAWAKLQASLTPGSSNTGSDLEAFSDHPAI
Protein: Regulator of hemoglobinization and erythroid cell expansion protein (Regulator of human erythroid cell expansion protein) (Q6ZWK4)
Organism: Homo sapiens (Human)
Function: Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25092874}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLTEVMEVWHGLVIAVVSLFLQACFLTAINYLLSRHMAHKSEQILKAASLQVPRPSPGHHHPPAVKEMKETQTERDIPMSDSLYRHDSDTPSDSLDSSCSSPPACQATEDVDYTQVVFSDPGELKNDSPLDYENIKEITDYVNVNPERHKPSFWYFVNPALSEPAEYDQVAM
Protein: GTPase activating protein, putative (Q38A99)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVGSRTIPTSTLGRNLRETEGAETDRFGFFISSEEKAMEEEFLRVHPEKLSVRERWSKALLRWDGCAHMKKKKLCRVGVPQSQRKTVWPLLLMTYGWQLEKYGDYHLLMSQQPRDAAMFEIIERDLGRTFPTHRLFNKPGSTGQMGLRSILRAYANLNPETGYVQGMGFLVGTLLIQIGDEESTFSAFVSIMENPRYSMAKLYAPGFPLLFVRLHQLQKLLGRHCKKLLKRLMEYGIELSTFAANWYLTLFAYHFNFGLLSRIWDMFLCEGWKIIHRVAIALLLLHKSALDRARDGAELLIALNTAHEGKDEVEVIRKALSVKFKTADLVRWERKFCQQL
Protein: Probable glutamine synthetase (Q9I6J3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Glutamate dehydrogenase
- Glutamate synthase large chain
- gamma-glutamyl-gamma-aminobutyrate hydrolase
- Glutaminase
- Assimilatory nitrite reductase large subunit
- Probable aldehyde dehydrogenase
- Glutamate synthase small chain
- Putrescine--pyruvate aminotransferase
- Bifunctional protein PutA
- Glutamine--fructose-6-phosphate aminotransferase
Sequence:
MTTKLDQLTSWLKERKITEVECLISDLTGIARGKISPTNKFIAEKGMRLPESVLLQTVTGDYVEDDIYYDLLDPADIDMVCRPDENAVFLVPWAIEPTAMVIHDTFDKLGNPIELSPRNILKRVLKMYADKGWRPIVAPEMEFYLTKRSDDPDYPLQAPVGRSGRQETGRQSFSIDAANEFDPLFEDMYDWCEAQGLDLDTLIHEEGTAQMEINFRHGDALDLADQILVFKRTMREAALKHNVAATFMAKPMTGEPGSAMHLHQSIVDVKTGKNIFSNADGTMSELFLHHIGGLQKFIPEVLPLFAPNVNSFRRFLPDTSAPVNVEWGEENRTVGLRVPDSSPENRRVENRLAGADANPYLALAASLLCGYIGMVEGIKPSAQVKGRGYERRNLRLPLTIEAALERMENCKPLEQYLGSKFISGYVAVKRAEHENFKRVISSWEREFLLLSV
Protein: DNA repair protein RAD5B (EC 3.6.4.-) (Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 3) (SMARCA3-like protein 3) (RAD5 homolog B) (AtRAD5B) (Q9FIY7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for DNA repair. Does not seem to be required for DNA repair and regulation of homologous recombination (HR).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mov34/MPN/PAD-1 family protein
- At1g80210/F18B13_28
- RuvB-like protein 1
- ATP-dependent DNA helicase Q-like 4B
- Actin-related protein 5
- Actin-related protein 4
- ATP-dependent RNA helicase DEAH12, chloroplastic
- Chromatin structure-remodeling complex protein SYD
- Protein EIN6 ENHANCER
- DEAD-box ATP-dependent RNA helicase 35
Sequence:
MAIVDDAEMRLTESEAVSSSDDRKIVADTPDFIDESSLVIRTTTGVRISALPAEQSLVDSDGSNSEVTLPAKDEVISDGFTCVNKEIVESDSFREQNLEIGEPDLDVENRKEAMIIDSIENSVVEIVSSASGDDCNVKVEVVEPELLVENLVVAKEEEEMIVDSIEDSVVEIVSTASGCDCNVKVEVVDPELCVDNLVVVKEEEMIADSIAESVVETVSRGLDYECVDVKVKEEPDLGTKLEEDSVFPNVLEKKDEVIKVLEDQPSEINKKLEQENDDLFSSGDSDGTSAKRRKMEMESYAPVGVESCILAPTPLRVVKPEKLDTPEVIDLESEKSYTHVKMEPVEEIKVEAVKMSSQVEDVKFSREQKSVYVKKEPVGARKVKVEDGDFPVEKDWYLVGRSLVTATSTSKGRKLEDNEIVNFTFSSVAKWKVPNIVRFSTKRCGEIGRLPMEWSNWAVSLLRSGKVKMLGRCVAAPPFLTMMQEIMLYVSFYIHSSIFTDVSKSTWRIGSSPNLESTLHPLLQLFKHLTIKPYQKAEFTPEELNSRKRSLNLEDDYDERAALLAIAKRRKGCQQSLEQNKDEEEAPESYMNRVVGAADSYNLEEMEAPSTLTCNLRPYQKQALYWMSESEKGIDVEKAAETLHPCWEAYRICDERAPSIYLNIFSGEATIQFPTATQMARGGILADAMGLGKTVMTIALILARPGRGNPENEDVLVADVNADKRNRKEIHMALTTVKAKGGTLIICPMALLSQWKDELETHSKPDTVSVLVYYGGDRTHDAKAIASHDVVLTTYGVLTSAYKQDMANSIFHRIDWYRIVLDEAHTIKSWKTQAAKATFELSSHCRWCLTGTPLQNKLEDLYSLLCFLHVEPWCNWAWWSKLIQKPYENGDPRGLKLIKAILRPLMLRRTKETRDKEGSLILELPPTDVQVIECEQSEAERDFYTALFKRSKVQFDQFVAQGKVLHNYANILELLLRLRQCCNHPFLVMSRADSQQYADLDSLARRFLDNNPDSVSQNAPSRAYIEEVIQDLRDGNSKECPICLESADDPVLTPCAHRMCRECLLTSWRSPSCGLCPICRTILKRTELISCPTDSIFRVDVVKNWKESSKVSELLKCLEKIKKSGSGEKSIVFSQWTSFLDLLEIPLRRRGFEFLRFDGKLAQKGREKVLKEFNETKQKTILLMSLKAGGVGLNLTAASSVFLMDPWWNPAVEEQAIMRIHRIGQKRTVFVRRFIVKDTVEERMQQVQARKQRMIAGALTDEEVRSARLEELKMLFR