Protein: Protein lava lamp (Q8MSS1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi-derived membrane secretion required for the formation of furrows during cellularization. Under starvation conditions recruited by ema to developing autophagsosomes where it may function in autophagosome growth.
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:11076973, ECO:0000269|PubMed:18327897}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:22493244}. Note=Lva-alpha-spectrin and Lva-CLIP-190 complexes are found at the Golgi (PubMed:11076973). Upon autophagosome induction by starvation, also detected in small vesicle structures (PubMed:22493244). {ECO:0000269|PubMed:11076973, ECO:0000269|PubMed:22493244}.
Interaction partners:
- Restin homolog
Sequence:
MAEDSGALESSYDFSIVQPDDHEYGEADIRLAGSSNDLSSLQNVSASTTRGTKGKGRLDSLKENLYKQQERLTALKERALRKSQDERHKSSMSDSMESLKTLGQKLTVLKTRSGDSSTPLVSPTKDSDPGDVSLLQTSGSEKLLMLTQRTEQNRALLEQRKRDLAKSLLSVKSNIGHQTTAELGSSMTDLRHAASVSNPPVSRHRSALDLEAQGQEAVDESRVKLLRSRMKLTELKQGRQEQELNELRTELAKRAKLIERLELSGAELQRTLTQRNEELEQLRVVQAEEDSLKVQENSRLQGEVLVLRERLAELENVNDLLETTRCELQEELTTARERQRNLELEQEQEKASRSPQSEAAHTDAQVSAELAKQLQELTNQLADLQATNEELRQQVAAQAKLQVTDEIVSQRLEELEATIAAQLLELQEQKSAMAAQNEELAEKTTELNVLNVNLRLLEEKLAQSSRSKPLFLEDHSEDSAASKQMQEDLQQLKLKLDETNKANIKLKLKCKQAEKKLQKFQSQDGQQQLASLLADNEELQQRIAVLEDEKGQWQLANMQEDDRQPEQSTESNNPLQLETIRLLEEQKLELQQALEALLSSSSSAESIEIVERHHLECLGQRRPASEGDAQEQKQVHPPGPSHVSELTQTEQTEEEDSSGETLSQLRERLELFTQERGEVLDKLEQLSAENLQLQARLEESSSSLQLLQREREKDLISSTSTSSNLSQELSSMQRSSEVVATLDAGEGGPVLFEKCEKSLSKLNSELEAYRKANDRQAKFNVSKKLAKEAKNCHTQLSELLHKVKEASTAVETVTVVETVVAVTAPNGKALAEYEQLNAQNAELKAVISRLRQELDELRESYPETEAPLAIVGSDSQREDEILQLQSQLEDARSLQAEQRQQIEEQVDQIKELRQTEAEQLQLVARQSAEITQLQLQSEQFDQLLNSKEMSHEKQLEQQTRIRRELEARAESLEGELSILQTLVAEQKQQLIESVSESEHALNLKMLELQSAQEELRELRAKEDPDQLREALRVSKSLVAQQVRELTSSQETVDALNQQIQEYQGLEHAHKEEQFKNRELREKLKKYALNLKKRTQDNADLEQKVQELTSQLQEQQELVKQKEEVEREPIVDNHRVEQLQQQVSKLNEDLKAKIHLNLENRDALRQLKQQIQEQEQLIQERDAELQDANLVSKELRRERQEADQEVFQLGQENSRLREEISKLQEEIHNLGQRVNEEPTAVEDLRRQLEAKSKKFEKSKELIKLRNATIQSLQRELQQLQQDQDSEVEHVRNARAAHEQLRLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQVAERELQQLRVQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIESLEAQNTELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQREQEEQKRQQDQQLQERFYELGQREQAQSRQLELLTSEAEESRQQLAGLRTEYESLLAKHSQLTATAQAEREQMSSHSQEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELECDLNSHVERAAAETRELCQQLERSQELVAQRTEELQRLNEEFQEVERERSTLSREVTLLRLQHDSAEQDVLELQELRMQAMQDKTEMDNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQVYIETENKRLAEQLSELQAQLARQQHQQQQQQHHHPAVQSQQHPPPASLFFGGDALAAPSPFDEIAQPLRVSSLAASAPPPISPPPTIEDLQRNVSDLEKHAQDLETKLLARNQNLAEQEERRLQLEQRLSEVERLLSERTQQLADIQTANEERDRLAALEKLIQPAAAPTLDMFFGGQAEETVPDAVSHHLDLGLPQTEPVVEPLIQPKKAYLCQPKQEIQEQTAQTIDWGVDEDPWASAANEAPQTDVEHLHTRIAQLELQLSNAEQQKTELQTKAAKLMKRLKEYKTKATTTATPTVTVDNDLDSTIIEELKHQLQLQESRLSKAEEISQQHALEKEKLAKRIDVLTAGNDRMAEMKERQDMDVQMYQARIRELQEKLSQLDQWGEPAATVSSSLDGDEAARIESLQQEIQQLRQQVSELEDERTRDQAELGALRQSSQGYDEAEDNQKLELQQLRQQESELEALRTRDQSELEALRQSCQGHDETVRIATLQQDNQQLELQQLRQAIIELETLRARDQTELEALRQSSQGHDEAARIAIEQRDNQQLELQQLRQQLIELEALRARDQAELEALRQSCQGQQLSVDMASRNDEQMAQLQEKESEIVHLKQRIEELMREDQTEKLVFEILTKNQELQLLRMQVKQLEEDKEDQQVSAAPPKDDGETVEKLKSLCQQLQQEKSDMEEELRVLNNHVLSSLELEDRMKQTLLQLDTKNIEITELRRSLEILQSQNLGQNSAAEQIPDLSAINQQWEQLVEQKCGEVASIWQEHLSQREAAFKAQLEEVTQQQQRELPQSQQSTQGEATSDIMQKMQKALETQEMEIVTLKEQLAIRSAEYARLAAQYDPFRLQNRGGASGGNPASTTVSAGGPPSLTANEPLPEYVLKADLDYALMMLHQRDMRVEEMIVELVQLLEERDHLQLKLSDTLRQLETERSRVSDEPSATASSSAASSSSPSKISSAGSNSELLGTTSAAGSDLKQKLAELQTVKHSKDKVIVDEREQRLQQMLQLQKDMAKQGSGSQSGAGAVAAVAAPTSAAPTAIGVDLSQSGLRSPSMMLMDWILGNNNKEEEAGHQTTG