wanglab/gogpt-training-data huggingface dataset:
Protein: Transcriptional regulatory protein RcsB (Capsular synthesis regulator component B) (P0DMC7)
Organism: Escherichia coli (strain K12)
Function: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. The system regulates expression of numerous genes, including genes involved in colanic acid capsule synthesis, biofilm formation, cell division and outer membrane proteins synthesis. Also involved, with GadE, in control of glutamate-dependent acid resistance, and, with BglJ, in derepression of the cryptic bgl operon. The RcsB-BglJ activity is probably independent of RcsB phosphorylation.
Interaction partners:
- Phosphotransferase RcsD
- Transcriptional regulatory protein RcsA
- Sensor histidine kinase RcsC
- Outer membrane lipoprotein RcsF
- Transcriptional activator protein BglJ
- CsgBAC operon transcriptional regulatory protein
- Transcriptional regulatory protein CpxR
- Transcriptional regulator GadE
- DNA-binding dual transcriptional regulator OmpR
- Putative membrane protein IgaA homolog
Sequence:
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD
Protein: SEFIR domain-containing protein (Q8C0E5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MNRSIPVEVDESEPFPSQLLKPIPEYSPEEELEPPAPNTRNMAPSSLSVLQCPPLKLANHQPVSQQVTCLRAKVLEEGEASFFRRHPELGKDISSCSSGASEPESELGALPPEHRFTLTEKRNRWLGSQLSAASPDTGHESDKSDPSLPNALADSFSGGQEMMPRPRPRPGPHRHRAAPDVPTIDTGYDSQPQDVLGIRQLERPLPLTSSCYLQDLPGPLRSRELPPQFELERYPMNAQLLPPHPSPQAPWNCQYYCPGGPYHHQVPHGHGYPPAAAYQQVLQPALPGQVLPGARARGPRPVQKVILNDSSPQDQEERPAQRDFSFPRLPRDQLYRPPSNGVEAPEESLDLPAELRPHGPKAPSLAAVPRPPSNPLARGTLRTSNLPEELRKVFITYSMDTAMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFISQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL
Protein: Dve-s protein (Q9TYH1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDFQSAMETFAEAWVAANAGQQSQALALTRAVNAAAVVASANAKSPNASSSASASLADLAVKKEHSISPPHSVVSVGVGVAGEDQHRRSSLQGVQEKLTQLQMQQQHHQQQQQQQQHQQQQQHHHHQQQAQQAGAGVGSGELAGRRSSEGTPPTAHPPTNSEGQALSSSTASSSQNATPKSDRERERERERDREERVERGSISCLPPAALGMAVGVQQAQHQEKLLSHPALDSRREFDVSKVNRE
Protein: Inositol monophosphatase 2 (IMP 2) (IMPase 2) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 2) (Q05533)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and involved in the inositol cycle of calcium signaling.
Interaction partners:
- Inositol-3-phosphate synthase
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Inositol monophosphatase 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
- Histidine biosynthesis trifunctional protein
- Imidazoleglycerol-phosphate dehydratase
- Histidinol-phosphate aminotransferase
- Glucose-6-phosphate isomerase
Sequence:
MVLTRQVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKGVTKITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY
Protein: Chaperone protein dnaJ 16 (AtDjB16) (AtJ16) (Protein ARG1-LIKE 1) (AtARL1) (Q8VXV4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a continuous role in plant development probably in the structural organization of compartments (By similarity). Seems to not be involved in gravitropism signaling pathway.
Subcellular location: Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- LETM1-like protein
- Mitochondrial proton/calcium exchanger protein
Sequence:
MPGHRSKSEKKDADKQLRRDPYEVLGVLRNSTDQEIKSAYRKLALKYHPDKTANDPVAADMFKEVTFSYNILSDPEKRRQFDSAGFEAVEAESQELELDLSSLGAVNTVFAALFSKLGVPIKTSVSATILEEALNGRVSVDPLVLGQAVSKKVEKQCAHFYAVTISEEEVSAGLVCRVESSSKSKFKLLYFDQEANSGLSLALQEDSKRTGKITSAGMYFLGFPVYRLDHTINSMAQAKDPETAFFKKLDGFQQCEVTELKAGTHVFAVYGDNFFKNVSYTIQVLCAAAFTQEKEDLRSVEAQILTKRAELAKFETEYREVLVQFTDMTSRYAQEMQSIDELLKQRNEIHSAYTTIPLMKRSSSKNRMRKSSFKKAAAKAPAPTEQEEEEEEEEEEEEESSRQKNKKPSTCDKSETLKKKSKWFNLHLKLDKKKPC
Protein: Uncharacterized protein (Q382G7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MASTDEVVLSENRALRVECEAQEVEIAQLKNYLHMSVTKPDLCFGQQRVTLNKCLNSFPEKAWQKLIDETPEVDSPAIITALEDQLADKNKHLTACLQEISNLRSRSGDGKTKPDSITDGNTAHLLSQITFLHNEVERLEQQVNAVRAAGKEELRVMTIEYNDKLQLREKENRLLTEQLRGRKNHLADGEDMAARTKTLESQLATALSEKSSLLIEKNNFLAKIRKLEAVIKERKNETSEALQVASQEHTVSNAQIKGLQEVIQVLSDERSSLRRELANLRSGMSSQKVHTETQTDTLPQVSSSVQTDVVPLAAKECQVDSCNQLNDPTTHSVQSLAHMLEIKCAECDDLRGRIDDISAIHGETVSILEVTKKRLEEEAEHKRLLSDDAEKLSLQVRSLQQKCSQYAASERELHVRLANVEDEKQQLIASSFSFEREKKGMEERLQQFQRDMDQLVANKNYCNQQVGQLANENEKLVTEQQRLLRHETQLAYSLKAKDGELQEVLSAYQNAVKEAESQRDAQRTIERELEVVRATLSSKEQSIIYLQEQVSQLHRRDQQSCLDLQTYEYENDQLHRKLVQSTSRVAQLETTCEELQQVSLAKDRAADELQQSLAELSKQLILKENECVLLQHRYESLQHDFSGVQSAYEADSRRCRELEDTNARLVVRGMLSSEHDEKFSSLQGEVKAAQVALQERESLLRTVQEQLQRERDTKERCMTELEAAQASLSEALSSKERLQQIVLDQAATLSHLSQ
Protein: Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (Cep110) (Cp110) (Q7TSH4)
Organism: Mus musculus (Mouse)
Function: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:O43303}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23807208, ECO:0000269|PubMed:30375385}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:23807208}. Note=Recruited early and then associates with the growing distal tips (PubMed:23141541). Recruited to the mother centriole by KIF24 (By similarity). Removed from centrioles by TTBK2, leading to initiation of ciliogenesis and localizes only to the daughter centriole in ciliated cells (PubMed:23141541). In cytotoxic T lymphocytes remains associated with the mother centriole during docking of the centrosome at the immunological synapse upon target contact (PubMed:26670998). Recruited at the distal end of the mother centriole by MPHOSPH9 (By similarity). {ECO:0000250|UniProtKB:O43303, ECO:0000269|PubMed:23141541, ECO:0000269|PubMed:26670998}.
Interaction partners:
- Centrosomal protein of 97 kDa
- Centrosomal protein of 290 kDa
- Ras-related protein Rab-8A
- Cyclin-F
- Serine/threonine-protein kinase PLK1
- Ubiquitin carboxyl-terminal hydrolase 33
- Kinesin-like protein KIF24
- Centrosomal protein of 76 kDa
- Serine/threonine-protein kinase PLK4
- Protein TALPID3
Sequence:
MEEYEEFCEKALGRAQEASLSTGSFLPAQAESVSLIRFHGVAVLSPLLTIEKRKKIQEEKQKALDVQSRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETIYSNPEVTDLNVPVRVPNSLPSPTEHCTSVKLEKITGLLPVNNEDQQTPKRVGLPGDSEVSGSLRQCESPESRQAEDGAALRLSSASPQETIISDVLGKEEQDPSCLAEVTPDPYIMSLQNLMKRSKEYVERELSSRSLRNSLKRSVNETHSDRENDAAKASDCVKEKAPPMPIGRHCGSAIPDKPSLNKSNVLLQGASQASSMGTAGLASFSKIDLPAGAAPPAAPDAGSDFTVIPTFVTENKVKSLKGPYAKLPSPEPSMSPTMHRRHSRSASACQILINNPVNACELSPKGKEEAVDRTAPAAAETTNESETVPKSPTDLTGVCSSNVSATKITSESTREMVVGKPSQRQQALGAHLGNNVTVERSAMEGPFIADDRGAQKVDGTCMAVPKLHELQPSSQCVSSQTLEDVCELKSASLLAKNSCNLQMELNKSYDVKHPSPLLTQTQTSRQQMDTPPVFRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPYIITAGVAEQERDRLLERRYPKGFVHINKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQEQLQKEIEEQEKMLKEKAVTTDVSDLNSALEWRQRTDSALLETMLSQVDSLQTSNNSGFITSALQYSFGSAGEAPFYLWGSLTSGVTRVSGTRPCGRAQAKWSQVFNPEIHAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSVATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI
Protein: Gastrokine-1 (18 kDa antrum mucosa protein) (AMP-18) (Protein CA11) (Q9NS71)
Organism: Homo sapiens (Human)
Function: Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
Subcellular location: Secreted {ECO:0000269|PubMed:15221938}. Cytoplasmic granule {ECO:0000269|PubMed:15221938}. Golgi apparatus {ECO:0000305|PubMed:15221938}. Note=Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus. {ECO:0000269|PubMed:15221938}.
Interaction partners:
- Calpain-9
- Gastric triacylglycerol lipase
- Gastrokine-2
Sequence:
MKFTIVFAGLLGVFLAPALANYNINVNDDNNNAGSGQQSVSVNNEHNVANVDNNNGWDSWNSIWDYGNGFAATRLFQKKTCIVHKMNKEVMPSIQSLDALVKEKKLQGKGPGGPPPKGLMYSVNPNKVDDLSKFGKNIANMCRGIPTYMAEEMQEASLFFYSGTCYTTSVLWIVDISFCGDTVEN
Protein: Kinesin light chain 3 (Q91W40)
Organism: Mus musculus (Mouse)
Function: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa. May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:28003339, ECO:0000305|PubMed:11319135}. Mitochondrion {ECO:0000269|PubMed:22561200}. Note=In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria (By similarity). Also localizes to the manchette in elongating spermatids (PubMed:28003339). {ECO:0000250|UniProtKB:Q68G30, ECO:0000269|PubMed:28003339}.
Interaction partners:
- Kinesin-1 heavy chain
- Kinesin heavy chain isoform 5A
- Kinesin heavy chain isoform 5C
- Kinesin light chain 2
- Kinesin light chain 1
- Kinesin light chain 4
- Glycogen synthase kinase-3 beta
- Neurofilament light polypeptide
- Alpha-synuclein
- Neurofilament heavy polypeptide
Sequence:
MSVQVAAPGSTGLGPERLNPEELVRQTRQVVQGLEALRAEHHSLAGHLAEALAGPGPVAGVELLEEKQQVVNHSLEAIELGLGEAQVLLALSAHVSVLEAEKQRLRAQARRLAQENTWLREELEETQRRLRASEEAVAQLEEEKSHLQFLGQLRQYDPPEESQRPESPPRRDSLASLFPSEEEEKKGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFQDVERHYARALSIYEALGGPQDPNVAKTKNNLASAYLKQNKYQQAEELYKEILSQEALPAPLGAPQGGTAGDTQQQVLRRSSSFSKLRESIRRGSEKLVSRLRGEGMAGAAGMKRAMSLNMLNVDGPRAARTQLSQLSTRHLSEAPRTLSISTQDLSPR
Protein: Ribonucleotide reductase inhibitor protein SML1 (Q04964)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Strong inhibitor of ribonucleotide reductase (RNR1) and is involved in regulating dNTP production.
Subcellular location: Nucleus {ECO:0000269|PubMed:20566477}. Cytoplasm {ECO:0000269|PubMed:20566477}.
Interaction partners:
- Serine/threonine-protein kinase MEC1
- Serine/threonine-protein kinase RAD53
- DNA damage response protein kinase DUN1
- Ribonucleoside-diphosphate reductase large chain 1
- Mediator of replication checkpoint protein 1
- Damage-regulated import facilitator 1
- DNA repair protein RAD9
- Serine/threonine-protein kinase TEL1
- DNA damage checkpoint protein LCD1
- Ribonucleoside-diphosphate reductase large chain 2
Sequence:
MQNSQDYFYAQNRCQQQQAPSTLRTVTMAEFRRVPLPPMAEVPMLSTQNSMGSSASASASSLEMWEKDLEERLNSIDHDMNNNKFGSGELKSMFNQGKVEEMDF
Protein: Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) (Q14166)
Organism: Homo sapiens (Human)
Function: Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3). Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20162578, ECO:0000269|PubMed:28011935}. Midbody {ECO:0000305|PubMed:20162578}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000305|PubMed:20162578}. Cytoplasm, cytoskeleton, spindle {ECO:0000305|PubMed:20162578}. Nucleus {ECO:0000269|PubMed:23251473}. Note=Predominantly localizes in the cytoplasm (PubMed:28011935). Partially colocalizes with vimentin in prostate cancer cells (PubMed:20162578). {ECO:0000269|PubMed:20162578, ECO:0000269|PubMed:28011935}.
Interaction partners:
- Protein PBDC1
- Elongation factor 1-alpha 1
- DnaJ homolog subfamily B member 1
- EEF1A lysine methyltransferase 1
- Elongation factor 1-alpha 2
- Tubulin monoglutamylase TTLL4
Sequence:
MEAERGPERRPAERSSPGQTPEEGAQALAEFAALHGPALRASGVPERYWGRLLHKLEHEVFDAGEVFGIMQVEEVEEEEDEAAREVRKQQPNPGNELCYKVIVTRESGLQAAHPNSIFLIDHAWTCRVEHARQQLQQVPGLLHRMANLMGIEFHGELPSTEAVALVLEEMWKFNQTYQLAHGTAEEKMPVWYIMDEFGSRIQHADVPSFATAPFFYMPQQVAYTLLWPLRDLDTGEEVTRDFAYGETDPLIRKCMLLPWAPTDMLDLSSCTPEPPAEHYQAILEENKEKLPLDINPVVHPHGHIFKVYTDVQQVASSLTHPRFTLTQSEADADILFNFSHFKDYRKLSQERPGVLLNQFPCENLLTVKDCLASIARRAGGPEGPPWLPRTFNLRTELPQFVSYFQQRERWGEDNHWICKPWNLARSLDTHVTKSLHSIIRHRESTPKVVSKYIESPVLFLREDVGKVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRAFALNDLDDYEKHFTVMNYDPDVVLKQVHCEEFIPEFEKQYPEFPWTDVQAEIFRAFTELFQVACAKPPPLGLCDYPSSRAMYAVDLMLKWDNGPDGRRVMQPQILEVNFNPDCERACRYHPTFFNDVFSTLFLDQPGGCHVTCLV
Protein: Septin-11 (B3GNI6)
Organism: Rattus norvegicus (Rat)
Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity.
Subcellular location: Cytoplasm, cytoskeleton. Synapse. Cell projection, dendritic spine. Cell projection, axon. Note=Partly colocalizes with stress fibers. Association with microtubules not observed in embryonic fibroblasts. In cultured hippocampal neurons, localizes to 54% of GABAergic and 25% of glutamatergic synapses. Frequently present at the base of dendritic protrusions and at the bifurcation points of the dendritic branches. Expressed at low levels in the axons of mature cultured hippocampal neurons. In embryonic fibroblasts, associated with actin stress fibers.
Interaction partners:
- Septin-5
- Septin-2
- Septin-9
- Septin-7
- Septin
- Septin
- Septin-8
- Neuronal-specific septin-3
- Septin-10
- Septin-1
Sequence:
MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNPWLCTE
Protein: Phosphoglycerate kinase (EC 2.7.2.3) (O60101)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P00560}. Mitochondrion {ECO:0000250|UniProtKB:P00560}.
Interaction partners:
- Phosphoglycerate mutase
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Glyceraldehyde-3-phosphate dehydrogenase 1
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Enolase 1-1
- Enolase 1-2
- Pyruvate kinase
- mRNA 3'-end-processing protein rna14
Sequence:
MSLSTKLAITDVDLKGKNVLIRVDFNVPLDGDRITNNARIVGALPTIKYALEQQPKAVILMSHLGRPNGARVAKYSLKPVAAELSKLLGKPVKFLDDCVGPEVEKACKEAKGGEVILLENLRFHIEEEGSAKVDGKKVKADASAVEAFRKSLTSLGDIFVNDAFGTAHRAHSSMVGVDLPRVSGFLMKKELDYFSKALENPARPFLAILGGAKVADKIQLIDNLLDKVNRLIICGGMAFTFLKVLNGMKIGDSLFDEAGSKNVESMMAKAKKNNVEVFLPVDFVTADKFDKDAKVGSATAEEGIPDGWMGLDCGPKSSAKFAEVITTSKTIVWNGPAGVFEFDNFAKGTKSMLDACVKTCEAGNVVIVGGGDTATVAKKYGKEDALSHVSTGGGASLELLEGKALPGVVALSSK
Protein: Tubulin alpha chain (Q19490)
Organism: Caenorhabditis elegans
Interaction partners:
- Tubulin beta chain
- Tubulin beta-4 chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta-2 chain
- Tubulin beta-1 chain
- Cytoplasmic dynein 2 heavy chain 1
- Dynein heavy chain, cytoplasmic
- Serine/threonine-protein kinase zyg-8
- WD_REPEATS_REGION domain-containing protein
Sequence:
MREIVSIHIGQAGVQIGNACWELYCLEHGITPDGLMPDDTSYGVEDQSYNTFFSETPSGKHVPRAIFVDLEPTVIDEVRTGTYAKLFHPEQLISGKEDAANNYARGHYTIGKELIDVVMDRVRRLTERCQSLQGFLIFHSFGGGTGSGFTSLVMERLSIDYGKKAKLEFSIYPAPQISTSMVEPYNSLLTTHTTLEHSDCSFIMDNEAIYEITKVNLGVRSPTYTHLNRLLAQVVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVSEITNVCFEPGSQMVKCDPRNGKYMACCLLYRGDVVPKEINSAISTIKTKRAIQFVDWCPTGFKVGINYQPPTVVPGGDMAKLQRAVCMLSNTTAIQEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSFDPNDEEY
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (G3V9W2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Interferon alpha/beta receptor 1
- Signal transducer and activator of transcription 1
- Signal transducer and activator of transcription 3
- Suppressor of cytokine signaling 3
- Interleukin-4 receptor subunit alpha
- Tyrosine-protein kinase
- Suppressor of cytokine signaling 1
- Interferon gamma receptor 1
- Interleukin-10 receptor subunit alpha
- Interferon gamma receptor 2
Sequence:
MQYLNIKEDCNAMAFCAKMRSFKKTEVKQVAPEPGVEVTFYLLDREPLRLGSGEYTAEELCIRAAQECSISPLCHNLFALYDESTKLWYAPNHIITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELSRCHSNDSGNVLYEVMVTGNLGIQWRQKPNVLPVEKEKNKLKRKKLDYNKHKKEDDRNKLREEWNSFSYFPEITHIVIKESVVSINKQDNKNMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVSCFEKSEVLGNQKQFKNFQIEVQKGRYSLHGSVDHFPSLRDLMNHLKKQILRTDNISFVLKRCCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGTLLDYKDDEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKQPITEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDFSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLSCPPNCPDEVYQLMRKCWEFQPSNRTTFQNLIEGFEALLK
Protein: Muscleblind-like splicing regulator 1 (A0A8I5Y4V0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM
Protein: Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1) (Q03407)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Activates YPK1 by phosphorylating of a threonine residue.
Interaction partners:
- Serine/threonine-protein kinase PKH2
- Protein kinase C-like 1
- Sphingolipid long chain base-responsive protein PIL1
- Sphingolipid long chain base-responsive protein LSP1
- [Pyruvate dehydrogenase
- Serine/threonine-protein kinase PKH3
- Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1
- Serine/threonine-protein kinase SCH9
- Serine/threonine-protein kinase YPK1
- Serine palmitoyltransferase 1
Sequence:
MGNRSLTEADHALLSKPLVPTSAEHTQTQEYPRPFVDGSNSQSGSELQASPQGQFGEKALTSTNRFIPLANDDPGMQHEMGLDPSMRRRREEWAERGAAKIVKDVVDPATGELTKHVVKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFEDGSVWDDNPPEIQPYKINAEAMKPLQKVSESDTTVKMANLQLAGNGHADTPLQAPAATSQEHSVISMTAATAAFNKDYTSQPKLGSKSSTSVRSASNNTDREVIQKKVSKNRASVSSPSISTTSRGKDNRSRSSDAFWSRYLQNMDERVLLMKEVALSTRNLEDSPVGLENVALDYKNPLDIEPPTDSAGKFYKKMFLITNLGRALVFVKRRSLSMWEEQEFELQFELELNDVEKIRFISDQVLEIDGSRTIFIGCKERAVLMKLWKLIHNGMTAKPKVVSPKSDHKMFDKFILQKRQNTKKKNQAPPVPQSNRLINGLPDRCILKTPEEGALHTKRPTSLQTRSSSNYSKLLARSTQMRKNMTRTDEK
Protein: Chromobox homolog 6b (Chromobox protein homolog 6) (X1WBY5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Polycomb complex protein BMI-1-B
- E3 ubiquitin-protein ligase RING2
- Polyhomeotic homolog 2b
- Polycomb group RING finger protein 5-A
- Nucleosome assembly protein 1-like 4a
- Polycomb group RING finger protein 5-B
- BAR/IMD domain-containing adapter protein 2-like 2
- Polycomb complex protein BMI-1-A
- Zinc finger protein 644b.
Sequence:
MELSAAGDRVFAAEAILKRRVRKGRMEYLVKWKGWAIKYSTWEPEENILDERLVAAFEQKEREQEMYGPKKRGPKPKTLLLKSRAQAESPRVPEFKHSRPQPHSKPPPPPPPAAPSYTPTAPSNAKLQSGTAQPKLKKDIHRCHRMARRPLPRQDHTVGPSGPFSSRPTVSAFSETVRILNRKVKPREVKKGRVILNLKVLDKAENTAVANNKRTHVPSTQQSHFGRQKIPSRNRVIGKNRRFGEVSYRGIQPPIRGSGFPVFGKLFDSHSLKNAESGESRNSMTNNLSSSQSSKLLDVSKGQNRNEEPPPSNSSSEVSDGEPPSPRQTQSQHSSLQPKASSTKSPSTKAPDPTLHKLGTQPVASKNKDSASSALPSSPMFSSSSSASTSSEDNEHILDLSVPHEMDRRLRRRHPFSGRHPLKVPEVPVSEEPSEEEEDLDWRPDMTSRCANVVVTDITANLLTVTIKEFCHPPSASSPPCYSKNVSTQNDTQQPKQNPNKT
Protein: CASP-like protein 1B2 (AtCASPL1B2) (Q9SUP0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:24920445}; Multi-pass membrane protein {ECO:0000269|PubMed:24920445}.
Interaction partners:
- Myb domain protein 9
- At3g02940
Sequence:
MAREKIVVAGGTTKSWKLLLGLRIFAFMATLAAAIVMSLNKETKTLVVATIGTVPIKATLTAKFQHTPAFVFFVIANVMVSFHNLLMIVVQIFSRKLEYKGLRLLSIAILDMLNATLVSAAANAAVFVAELGKNGNKHAKWNKVCDRFTTYCDHGAGAIIAAFAGVILMLLVSAVSISRLLINSKNFSTTATTTSVV
Protein: Uncharacterized RNA-binding protein C106.12c (Q9URV0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- ATP-dependent RNA helicase uap56
- Uncharacterized protein P25A2.03
- mRNA export factor mex67
- THO complex subunit Tho3
- ATP-dependent RNA helicase fal1
- Uncharacterized protein C126.13c
- Protein mago nashi homolog
- THO complex subunit 2
- Uncharacterized RNA-binding protein C23A1.09
- mRNA export protein mlo3
Sequence:
MSLEKSLDEIINERTNGFDHKHSRRRGSQNRISKKSRLTYKFKRASKEHNSSPDDGPWQHDLDQEQDAHPRTTHLQKRQHSENRFGVRVENLHYQVLEKDVLSLFENFHPIRVIMNYDRAGRSEGSCDVYFETSQDAEDAQKTLQSTNLKGSEIQISKKSPPSLFDRISDMPHSARKPSRSSRSNRGFNRSSKKDDRSFRSSSKKSSNNSISHEDLDKELDEYAMSFHAASTVSSHSSQDFTPSIANAHEKNEPVAPSKDSNLTEEMDLQMEAV
Protein: LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2) (P36198)
Organism: Rattus norvegicus (Rat)
Function: Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- LIM domain binding 1
- Cbp/p300-interacting transactivator 2
- SIX homeobox 3
- LIM domain binding 2
- T-box brain transcription factor 1
Sequence:
MLFHSLSGPEVHGVIDEMDRRQERGSGISSAIDRGDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISESEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPPHFNHADVARAAAAAEQLRVQDWAQLGLTLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKTSDATLQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEATSPTALHKRLLPTFSNDSPPPSPLSPHDFFKKEIIFS