wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein (Q38EC2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSTHTSSQSHLTRWEGATIRRCRRLHSAAQNGAVVGYVGECCQSSPVFVPIPPRQFLTRPRLFHHYRLYADSIPAALSCNPADRDYDYSWFTMPRVRKSSTVSKTKRRLREKLIAGRVPLSSIPEGTSGLFDSGRMDSPIRRCAKGLNSIQADAERCWDSDSSCEQLSPTEPGVLKDDSVLLVRPVAEEIPSELEIMTDEYSRVAPKGREWDRQYALRHCVGRTAQEAIVDCLIDTRYRRPGDYVRRNDRGQLVDACGRPARGNSRRRRG
Protein: E74 like ETS transcription factor 1 (G3V9V2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004019}.
Interaction partners:
Sequence:
MAAVVQQNDLVFDFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNGYAGLACVEEPNDMITESSLDVAEEEIIEDDDDDITLTVEASCHNGDETIETIGAAEALLNMDSPGPVLDEKRINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQESNADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKSKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEGPSSSTESSDQSLSSTTTSSRNQANRTRMSSSPGIKGGATTILKPGNPKVAKPKDTVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAIPEEATITSTMQEEAAGSSVQGIRTIQASTQVPVVVSPGNQQLHTVTLQTVPLTTVIASTDPSSGAGPQKFILQAIPSSQPMTVLKENVLLQSQKPGSPPSIVFSPTPVQQVLTGSVQSLGNGAVSMASPPNFSATAPVVTFSRSSQLAAHPPGTVITSVIKAQETKTPKAEVEKKAEGHLNGDPEEIEQQPQPYVMVVSSSNGFSSQVAITQNELLEPSSF
Protein: Vacuolar protein sorting-associated protein 37A (Q6TH08)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Late endosome membrane {ECO:0000256|ARBA:ARBA00004633}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004633}.
Interaction partners:
Sequence:
MNWIFPLSKGSGSIPPLNSLQKQRQRQIESLKAAHSNIAEIQKDVEYRLPFTVNNSTITVNILLPPQFPQEKPVVSVFPPVGHHLVDGNNGTMVTSPLIANFGMHSDLGKVIQSLLDEFWKSPPALMSDPTFPYMYKPSAMPPYPTQSFHFVPAFQPQDGQRPIGPAPVPHAGMEPQQAPPRPAAPAYGLITDLPLPVPTADSQSGLNGHIYKMPDIPDTFSELSEMSVSQLKDMSDQDDVLLDFFMCLPQLKQVTSDKEELVNSIVEMAKKNLQLEPQLEGKRQEMLCKYEQLTQMKSVFETKMQRQHELSESCSLSALQARLKVAAHQAEEESEETAENFLEGKTEIDDFLASFMEKRTLCHSRRAKEEKLQQCMNTHGQFPATL
Protein: Small ribosomal subunit protein uS19 (40S ribosomal protein S15) (Q6Q421)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein uS13
- Mitochondrial ribosomal protein S6.
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein uS5
- 60S ribosomal protein L7a
- Small ribosomal subunit protein uS11
- Large ribosomal subunit protein bL32m
Sequence:
MADTEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQQSLLKRLRKAKKEAPPMEKPEVVKTHLRDMVILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK
Protein: Coenzyme A biosynthesis bifunctional protein CoaBC (DNA/pantothenate metabolism flavoprotein) (Phosphopantothenoylcysteine synthetase/decarboxylase) (PPCS-PPCDC) [Includes: Phosphopantothenoylcysteine decarboxylase (PPC decarboxylase) (PPC-DC) (EC 4.1.1.36) (CoaC); Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (CoaB) (Phosphopantothenoylcysteine synthetase) (PPC synthetase) (PPC-S)] (P0ABQ0)
Organism: Escherichia coli (strain K12)
Function: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
Interaction partners:
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- Phosphopantetheine adenylyltransferase
- Pantothenate kinase
- Pantothenate synthetase
- Dephospho-CoA kinase
- Nucleoside triphosphate pyrophosphohydrolase
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- Nucleoid occlusion factor SlmA
- Acyl carrier protein phosphodiesterase
- Cystathionine beta-lyase MetC
Sequence:
MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGMANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEIVTRYDEKNRR
Protein: Cofilin-2 (Q966T6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Cofilin-2 may play a distinct role from that of cofilin-1 in destabilization of the actin cytoskeleton during Dictyostelium development.
Subcellular location: Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localizes at substrate adhesion sites. {ECO:0000269|PubMed:11683919}.
Interaction partners:
Sequence:
MSAPLSPSPTVVKLSPECQQYYQDVRIKNKYQGVVYKINKESNQMIIDKTFPNDCNFNELTQCFKENECCIIVFKYVISNSQSKLFFIYWGSETAPQTDKVLYSNAKLTLAITLKGIDIKIAGTKKSELTEEIFKERAIPKQA
Protein: Homeobox protein engrailed-like ceh-16 (P34326)
Organism: Caenorhabditis elegans
Function: Transcriptional regulator which binds to DNA to regulate gene expression and promote seam cell development and differentiation during embryogenesis. Plays a role in maintaining the boundaries between the lateral rows of seam cells and the ventral and dorsal row of epidermal cells during embryonic development. Negatively regulates the expression of the fusion effector protein eff-1 to prevent seam cell fusion with the dorsal and ventral epidermal cells during embryonic elongation. Positively regulates seam cell self-renewal and expansion during the L2 larval stage to promote seam cell development. This role does not seem to be via regulation of eff-1 expression. Specifically, it is required for the asymmetric division of the V5.p seam cell during the L2 larval stage, and in turn the asymmetric nuclear distribution of pop-1 in V5.p daughter cells.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:15659483, ECO:0000269|PubMed:19607822}. Cytoplasm {ECO:0000269|PubMed:19607822}.
Interaction partners:
- Transcription factor unc-37
Sequence:
MILKFGIERILSSPYPCPSPTISTPATSPSSISPTFASPNGTPNIASSMYPAWVFSTRYSDRPSAGPRHRKSRKRESTGSSGSSEEEKRPRTAFTGDQLDRLKTEFRESRYLTEKRRQELAHELGLNESQIKIWFQNKRAKLKKSTSSVPRDRCSSVTPNPHNHPSIHGGYQLMAQLAKVQARAYMP
Protein: Elongator complex protein 4 (A0A1W2PQZ6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIEVREFLCFSLQS
Protein: Serotransferrin (Q9PT13)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|PIRNR:PIRNR002549}.
Interaction partners:
Sequence:
MKLLLVSALLGCLATVYAAPAEGMVRWCVKSDKELQKCHDLAANVAQFSCVRRDNSLECIQAIKREEADAITLDGGDIYIAGLHNYNLQPIIAEDYGEDSDTCYYAVAVAKKGTDFGFLNLRGKKSCHTGLGKSAGWNIPIGTLVTVGQIQWAGIEDRPVESAVSDFFNASCAPGANKDSKLCQLCKVDCSRSHNEPYYDYAGAFQCLKDGAGEVAFIKHLTVPAAEKASYELLCKDNTRAPIDSYKTCHLSRVPAHAVVSRKNPELANRIYSKLMAVENFNLFSSDGYAAKNLMFKDSTQNLVQLPMTTDSFLYLGAEYMSTIRSLTKAQATGATSRAIKWCAVGHNEKVKCDAWTINSFTDGDSRIECQDAPTVDECIKKIMRKEADAIAVDGGEVFTAGKCGLVPVMVEQYDAVQCSAPGEASSYFAVAVAKKGSGVTWNTLQGKRSCHTGLGRTAGWNIPMGLIHKETNNCDFTTYFSKGCAPGFEVDSPFCAQCKGGGQSVGGDRARCIASSEEQYYGYTGAFRCLVEGAGDVAFIKHTIVPENTDGSGPVWAQDLKSSDFELLCQDGTTQPVTKFRDCHLAKVPAHAVITRPESRGEVVSILLEQQARFGSSGSDSSFNMFQSDLGKNSLFKDSTKCLQEIPSGTKFQDFLGEEYMIAMQSLRECSNSTSDLEKACTFHSCQQKK
Protein: Protein MGR2 (Mitochondrial genome-required protein 2) (Q02889)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for cell viability in cells lacking mitochondrial DNA.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM21
- Mitochondrial import inner membrane translocase subunit TIM17
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit TIM14
- Mitochondrial import inner membrane translocase subunit TIM16
- Mitochondrial import inner membrane translocase subunit TIM44
- Mitochondrial import inner membrane translocase subunit TIM23
- Presequence translocated-associated motor subunit PAM17
- Import motor subunit, mitochondrial
- GrpE protein homolog
Sequence:
MPPLPQNYAQQQPSNWDKFKMGLMMGTTVGVCTGILFGGFAIATQGPGPDGVVRTLGKYIAGSAGTFGLFMSIGSIIRSDSESSPMSHPNLNLQQQARLEMWKLRAKYGIRKD
Protein: Signal transducer and activator of transcription (Q9QXK0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
Sequence:
MSQWFELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAAYDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPVQMSMIIHNCLKEERKILENAQRFNQAQEGNIQNTVMLDKQKELDSKVRNVKDQVMCIEHEIKTLEDLQDEYDFKCKTSQNRESEANGVAKSDQKQEQLLLHKMFLMLDNKRKEIIHKIRELLNSIELTQNTLINDELVEWKRRQQSACIGGPPNACLDQLQSWFTIVAESLQQVRQQLKKLEELEQKFTYEQDPITKNKQVLSDRTFVLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVSFDKDVNEKNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVTEPRNLSFFLNPPCAWWSQLSEVLSWQFSSVTKRGLNADQLSMLGEKLLGPNAGPDGLIPWTRFCKENINDKNFSFWPWIDTILELIKKHLLCLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDDPKRTGYIKTELISVSEVHPSRLQSTENLLPMSPEEFDEMSKIVGSEFDSMMSAV
Protein: 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) (P28334)
Organism: Mus musculus (Mouse)
Function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Subcellular location: Cell membrane {ECO:0000269|PubMed:1557407, ECO:0000269|PubMed:17325130}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- Guanine nucleotide-binding protein G
- Protein S100-A10
- Basigin
- 5-hydroxytryptamine receptor 1D
- Sodium-dependent serotonin transporter
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
Sequence:
MEEQGIQCAPPPPAASQTGVPLTNLSHNCSADGYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEMLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCAG
Protein: Anosmin 1b (Anosmin-1b precursor) (Q1MT36)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Fibroblast growth factor receptor 1-A
- Prokineticin
Sequence:
MLLLRNLCCFLLCCVFEVSVARRTEEAESLEKMESARCVSRCLTLHITQITAAFRHLQNDRVLGWCENHRRCSQCLQPCKELWETRRALSPKTCEHHECVTSAEFLRSLRVQKQGDCPPAQRASGFAAACVESCARDRECSGVKKCCSNGCGHTCQSPANLFKGVPLKPRRDISFSEDHQGHVKVTWMSKFNVSVEPVLYVLQRRWNHGIHPSEDEASAWQTVLMTMEDRSVLKDIRPHRWYQFRVSAVNSQGTRGFTTPSKHFFSVRDPLPPETPQNARTANQTLHPDGTVSVLVLWETPRESDLVVHHHKVTWSPRGTPSSSQSRAGRVTDGDVTQMELQGLQPNTPYTAQIQAISYWGQNRLKSSRAHISFTTTSQNSATSSNGEFSNELPVSHSSPSVLRLEAAAPHYHDNQLQVKVFWKSRVQESQKDSSSYILRWYPEVCSHNVTKDEKTATVQGTHYVITGLLFACKYRVAVKPVAEQRSEVTTSVTTPLCLSLMGRRKKPAACAREERHPQLKKALRRPEKLAVLFQPVNGSLQALFSWQLSPESSGQTPSSGFQFSWVKVSSGSSNGSLISQTHILPPDQLSLTVDALQPSSVYRVQVQVLSEAGNGPSVAKTLHTPALNSTIH
Protein: Caytaxin (Ataxia cayman type protein) (BNIP-2-homology) (BNIP-H) (Q86WG3)
Organism: Homo sapiens (Human)
Function: Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites.
Subcellular location: Cell projection, axon {ECO:0000250|UniProtKB:Q1M168}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q1M168}. Presynapse {ECO:0000269|PubMed:16899818}. Mitochondrion {ECO:0000250|UniProtKB:Q1M168}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q1M168}. Cytoplasm {ECO:0000269|PubMed:16899818}.
Interaction partners:
- Alpha-tocopherol transfer protein
- Kinesin light chain 1
- Peptidyl-prolyl cis-trans isomerase FKBP1C
Sequence:
MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTLNFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTHGGYYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEEKPEVAPVENRSALVSEDQETSMS
Protein: Kunitz-type serine protease inhibitor RsTIS5 (P84556)
Organism: Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)
Function: Serine protease inhibitor. Inhibits trypsin, elastase and plasmin. Does not inhibit kallikrein.
Interaction partners:
Sequence:
EAEPKPFNPVCYEPKEVGPCKAYVP
Protein: WH2 domain-containing protein (H2KZ22)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MPPPPPPPPPPPPPPPPAASAPPPSSNARNALLGDIHKGLKLKKTVTNDRSAPSVGKVVGSSGSSSNGNSGNGNGPAAKPPQMSGGLGGLFANGMPMKPSENKIRRATTSIGPPPTASSAPPVPPPAPVPAVEGKKPSIVSSSSFSHHGATSSAPPPPPPPPPVSVPSSKPTPPPPPPAQQKPSSDREQFRTMRPLRPANDVKPTMYRRSGSSEDIPQATSATRLARPLAPPPARPAAPPPPVPTPSIAQMSSRFQSPAISRTLDDAPPPPPRIASKTSVAPTSSRAPLPPSSSFAPSISASPAPAPPPPPPQAASPYPGMKSTATVSANVPFHPLNRFHFLPLSQLPPPPKVSSGSIRA
Protein: Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1) (Q5T0N5)
Organism: Homo sapiens (Human)
Function: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16757518}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- Actin nucleation-promoting factor WASL
- Cell division control protein 42 homolog
- Actin nucleation-promoting factor WAS
- WAS/WASL-interacting protein family member 1
- Formin-binding protein 1
- Ubiquitin-like-conjugating enzyme ATG3
- Sequestosome-1
- Actin-binding protein WASF1
- tRNA-splicing endonuclease subunit Sen2
- F-BAR domain only protein 2
Sequence:
MSWGTELWDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSCVAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDNDTNATKADVEKAKQQLNLRTHMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTISASKQESGKMDAKTTVGKAKGKLWLFGKKPKPQSPPLTPTSLFTSSTPNGSQFLTFSIEPVHYCMNEIKTGKPRIPSFRSLKRGWSVKMGPALEDFSHLPPEQRRKKLQQRIDELNRELQKESDQKDALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEGKTGGRGDRRHSSDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGHHNEFDDEFEDDDPLPAIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYIDVTLEKNSKGS
Protein: Glutathione peroxidase (Q6JAH6)
Organism: Zea mays (Maize)
Interaction partners:
- Glutathione reductase
- Glutathione reductase
- Glutathione hydrolase
- Dehydroascorbate reductase
- Glutathione synthetase, chloroplastic
- Chromatin modification-related protein EAF3
- glutathione transferase
- glutathione transferase
- glutathione transferase
- glutathione transferase
Sequence:
MAASSTATSVHDFIVKDASGKDVDLSTYKGKVLLIVNVASQCGLTNSNYTELAQLYEKYKDQGFEILAFPCNQFGGQEPGTNEEIVQFACTRFKAEYPIFDKVDVNGSNAAPIYKFLKSSKGGLFGDSIKWNFSKFLVDKEGRVVDRYAPTTSPLSIEKDIKKLLGSS
Protein: Histone H1t (Testicular H1 histone) (Q07133)
Organism: Mus musculus (Mouse)
Function: Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration.
Subcellular location: Nucleus {ECO:0000305}. Chromosome {ECO:0000305}.
Interaction partners:
- Histone H1.8
- Testis-specific H1 histone
- Synaptonemal complex protein 3
Sequence:
MSETAPAASSTLVPAPVEKPSSKRRGKKPGLAPARKPRGFSVSKLIPEALSTSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKMGLPRASRSPKSSKTKAVKKPKATPTKASGSGRKTKGAKGVQQRKSPAKARAANPNSGKAKMVMQKTDLRKAAGRK
Protein: Beta-1,4-galactosyltransferase (Beta-1,4-GalTase) (EC 2.4.1.-) (Q99PC2)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU368121}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU368121}.
Interaction partners:
Sequence:
MRFLRPVLGGSAAMPGATLQRACRLLVAVCALHLGVTLVYYLSGRDLSRLPQLVGVSSTLRSGTIGATANKQPPGARPPPPVGVSSKPRPGPDSSPGTAFDPGLKSNWTSVLVPPTTALLTLPACPEESPLLVGPMVIDFNIAVDLELLAKKNPEIKMGGRYSPKDCISPHKVAIIIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTMFNRAKLLNIGFQEALKDHDYNCFVFSDVDLIPMDDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLAINGFPNNYWGWGGEDDDIFNRIVHKGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMRFDGLNSLTYQVLNVERYPLYTKITVDIGTPR
Protein: Fibroblast growth factor 13 (FGF-13) (Q9ERW3)
Organism: Rattus norvegicus (Rat)
Function: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channels transport and function (By similarity). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity).
Subcellular location: Cell projection, filopodium {ECO:0000250|UniProtKB:P70377}. Cell projection, growth cone {ECO:0000250|UniProtKB:P70377}. Cell projection, dendrite {ECO:0000250|UniProtKB:P70377}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P70377}. Cytoplasm {ECO:0000250|UniProtKB:P70377}. Nucleus {ECO:0000250|UniProtKB:P61329}. Note=Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes. {ECO:0000250|UniProtKB:P70377}.
Interaction partners:
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 1 subunit alpha
- Sodium channel protein type 3 subunit alpha
- Calmodulin-1
Sequence:
MAAAIASSLIRQKRQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSEHFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
Protein: Chitinase 2 (EC 3.2.1.14) (Class I chitinase b) (OsChia1b) (Pathogenesis related (PR)-3 chitinase 2) (Q7DNA1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Hydrolyzes chitin and plays a role in defense against fungal pathogens containing chitin. Its overexpression confers enhanced resistance to sheath blight pathogen (R.solani).
Interaction partners:
Sequence:
MSTPRAAASLAKKAALVALAVLAAALATAARAEQCGAQAGGARCPNCLCCSRWGWCGTTSDFCGDGCQSQCSGCGPTPTPTPPSPSDGVGSIVPRDLFERLLLHRNDGACPARGFYTYEAFLAAAAAFPAFGGTGNTETRKREVAAFLGQTSHETTGGWPTAPDGPFSWGYCFKQEQNPPSDYCQPSPEWPCAPGRKYYGRGPIQLSFNFNYGPAGRAIGVDLLSNPDLVATDATVSFKTALWFWMTPQGNKPSSHDVITGRWAPSPADAAAGRAPGYGVITNIVNGGLECGHGPDDRVANRIGFYQRYCGAFGIGTGGNLDCYNQRPFNSGSSVGLAEQ
Protein: Protein argonaute 5 (Q9SJK3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates with siRNAs of various sizes, from 21-24 nucleotide in length and preferentially recruits small RNAs with a 5' terminal cytosine. Probably involved in antiviral RNA silencing. Associates with siRNAs derived from cucumber mosaic virus (CMV). Targeted by the turnip yellows virus (TuYV) protein P0 (via F-box-like domain) for probable proteasome degradation and thereby inactivating AGO5 function in RNA silencing.
Interaction partners:
- Dicer-like protein 4
- Endoribonuclease Dicer homolog 3
- Endoribonuclease Dicer homolog 2
- Endoribonuclease Dicer homolog 1
- RNA-dependent RNA polymerase 6
- Protein DCL homolog, chloroplastic
- RNA-dependent RNA polymerase 2
- DNA-directed RNA polymerase IV subunit 1
- Small RNA 2'-O-methyltransferase
- Probable RNA-dependent RNA polymerase 3
Sequence:
MSNRGGGGHGGASRGRGGGRRSDQRQDQSSGQVAWPGLQQSYGGRGGSVSAGRGRGNVGRGENTGDLTATQVPVASAVSGGRGRGNIGDPTFSVASSSKTVSVASSSKEESKNTEVSETMSNLQITSTETKPEMTSLPPASSKAVTFPVRPGRGTLGKKVMVRANHFLVQVADRDLYHYDVSINPEVISKTVNRNVMKLLVKNYKDSHLGGKSPAYDGRKSLYTAGPLPFDSKEFVVNLAEKRADGSSGKDRPFKVAVKNVTSTDLYQLQQFLDRKQREAPYDTIQVLDVVLRDKPSNDYVSVGRSFFHTSLGKDARDGRGELGDGIEYWRGYFQSLRLTQMGLSLNIDVSARSFYEPIVVTDFISKFLNIRDLNRPLRDSDRLKVKKVLRTLKVKLLHWNGTKSAKISGISSLPIRELRFTLEDKSEKTVVQYFAEKYNYRVKYQALPAIQTGSDTRPVYLPMELCQIDEGQRYTKRLNEKQVTALLKATCQRPPDRENSIKNLVVKNNYNDDLSKEFGMSVTTQLASIEARVLPPPMLKYHDSGKEKMVNPRLGQWNMIDKKMVNGAKVTSWTCVSFSTRIDRGLPQEFCKQLIGMCVSKGMEFKPQPAIPFISCPPEHIEEALLDIHKRAPGLQLLIVILPDVTGSYGKIKRICETELGIVSQCCQPRQVNKLNKQYMENVALKINVKTGGRNTVLNDAIRRNIPLITDRPTIIMGADVTHPQPGEDSSPSIAAVVASMDWPEINKYRGLVSAQAHREEIIQDLYKLVQDPQRGLVHSGLIREHFIAFRRATGQIPQRIIFYRDGVSEGQFSQVLLHEMTAIRKACNSLQENYVPRVTFVIVQKRHHTRLFPEQHGNRDMTDKSGNIQPGTVVDTKICHPNEFDFYLNSHAGIQGTSRPAHYHVLLDENGFTADQLQMLTNNLCYTYARCTKSVSIVPPAYYAHLAAFRARYYMESEMSDGGSSRSRSSTTGVGQVISQLPAIKDNVKEVMFYC