wanglab/gogpt-training-data huggingface dataset:
Protein: Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III subunit 1) (Core protein I) (Ubiquinol-cytochrome-c reductase complex core protein 1) (Q68FY0)
Organism: Rattus norvegicus (Rat)
Function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity). The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP) subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties. May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (By similarity). Seems to play an important role in the maintenance of proper mitochondrial function in nigral dopaminergic neurons (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P07256}; Peripheral membrane protein {ECO:0000250|UniProtKB:P07256}; Matrix side {ECO:0000250|UniProtKB:P07256}.
Interaction partners:
- Cytochrome b-c1 complex subunit 6, mitochondrial
- Cytochrome b-c1 complex subunit 10
- Ubiquinol-cytochrome c reductase, complex III subunit X.
- Cytochrome b-c1 complex subunit 8
- Cytochrome b-c1 complex subunit 10
- Cytochrome b-c1 complex subunit 7
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Cytochrome b
Sequence:
MAASAVCRAACSGTQALLRTCRSPALLRLPALRGTATFVQALQSVPETQVSVLDNGLRVASEQSSHPTCTVGVWIDVGSRYETEKNNGAGYFLEHLAFKGTKNRPGNALEKEVESIGAHLNAYSTREHTAYLIKALSKDLPKVVELLADIVQNISLEDSQIEKERDVILREMQENDASMQNVVFDYLHATAFQGTPLAQAVEGPSENVRRLSRTDLTDYLSRHYKAPRMVLAAAGGVKHQQLLDLAQDHFSSVSQVYEEDAVPSITPCRFTGSEIRHRDDALPLAHVAIAVEGPGWANPDNVALQVANAIIGHYDCTYGGGVHLSSPLASVAVANKLCQSFQTFNISYSETGLLGAHFVCDAMSIDDMIFFLQGQWMRLCTSATESEVTRGKNILRNALISHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIEEVDAQMVREVCSKYFYDQCPAVAGYGPIEQLSDYNRIRSGMFWLRF
Protein: Candida glabrata strain CBS138 chromosome B complete sequence (Q6FXP0)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Small ribosomal subunit protein eS25
- RP28
- Candida glabrata strain CBS138 chromosome M complete sequence
- L17A
- Large ribosomal subunit protein uL30
- Small ribosomal subunit protein uS14
- L33
- 40S ribosomal protein S7
- Candida glabrata strain CBS138 chromosome G complete sequence
- Candida glabrata strain CBS138 chromosome K complete sequence
Sequence:
MSRPQVTVQSLTGEATSSSVPLPAVFAAPIRPDLVHSVFVSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTHRSGQAAFGNMCRGGRMFAPTKTWRKWNVKVNQNEKRYATASAIAASAVASLVLARGHRVEKIPEIPLVVSKDLESIKKTKEAVAALKAVGAGADLLKVIKSKKMRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETVPVTALNLLQLAPGAHLGRFVIWTEAAFAKLDQVWGSETVASSKTGYSLPSNIVATTDITRIINSSEIQAAVRPAGQPSQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAAKSSTKPSAVFTETLKHD
Protein: Synoviocyte proliferation-associated in collagen-induced arthritis 1 (G1UCX3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDRNPSPPPPGRDKEEEEEVAGGDCIGSTVYSKHWLFGVLSGLIQIVSPENTKSSSDDEEQLTELDEEMENEICRVWDMSMDEDVALFLQEFNAPDIFMGVLAKSKCPRLREICVGILGNMACFQEICVSISSDKNLGQVLLHCLYDSDPPTLLETSRLLLTCLSQAEVASVWVERIQEHPAIYDSICFIMSSSTNVDLLVKVGEVVDKLFDLDEKLMLEWVRNGAAQPLDQPQEESEEQPVFRLVPCILEAAKQVRSENPEWLDVYMHILQLLTTVDDGIQAIVHCPDTGKDIWNLLFDLVCHEFCQSDDPPIILQEQKTVLASVFSVLSAIYASQTEQEYLKIEKVDLPLIDSLIRVLQNMEQCQKKPENSAESNTEETKRTDLTQDDFHLKILKDILCEFLSNIFQALTKETVAQGVKEGQLSKQKCSSAFQNLLPFYSPVVEDFIKILREVDKALADDLEKNFPSLKVQT
Protein: Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) (Q80Y56)
Organism: Mus musculus (Mouse)
Function: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3). Plays a role in the recycling of transferrin receptor to the plasma membrane (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Early endosome membrane {ECO:0000250|UniProtKB:Q9H1K0}; Lipid-anchor {ECO:0000250}. Note=Enriched in endosomes that are in close proximity to clathrin-enriched regions at the cell surface (By similarity). {ECO:0000250|UniProtKB:Q9H1K0}.
Interaction partners:
- Vacuolar protein sorting-associated protein 45
- Ras-related protein Rab-4A
- EH domain-containing protein 1
- EH domain-containing protein 3
- Ras-related protein Rab-4B
- Ras-related protein Rab-22A
- Ras-related protein Rab-5A
- Rab11 family-interacting protein 2
- Rab5 GDP/GTP exchange factor
- Rabankyrin-5
Sequence:
MASLDDPGEVREGFLCPLCLKDLQSFYQLQSHYEEEHLEDRDVKGQIKNLVQKARKAKNKLLKREGDDRVEPGTQGYESFSYGGVDPYMWEPQELGAMRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTAFDRTNTETSKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELIGLPLAHKLTSASKDSLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDKLLKREQQMDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYNLEHANDLRVEVQKVYELIDALSKKILTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDLEQKRTVERQAALESRRKLEERQSGLASHTANGDVRSLRGIPPPLRKAEGWLPLSEGQGQSEDPDPLLQQIYNITSFIRQAKAAGRTDEVRTLQENLRQLQDEYDQQQTEKAIELSRKQAEEEELQREQLQMLRKRELEREQEQFLAASLQTRTRVLELREVIPFQLEASRGPHIDLSYSLDQDSSPVQSSTAPDILTPGSALAPMHLWSGPPALGQETLPQSTMSQQSDKASLNPFDEDDLSSPTEGAISPAAVEAFLGPPAAVTKEYNPFEEDAEEEEVAELGAGNPFTDPDSPAPNPFDEDDGPRPASPAAPGNPFEECPSTNPFEVDSDSGMEAEEHIEEELLLQQIDNIKAYIFDAKQCGRMDEVEVLTENLRELKCTLAKQKGAPN
Protein: Metalloendopeptidase (EC 3.4.24.-) (F1M798)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Periostin
- Chordin
- Protein-lysine 6-oxidase
- Apolipoprotein A-I
- Inactive rhomboid protein
- Thimet oligopeptidase
- Collagen type V alpha 2 chain
- Collagen alpha-1
- protein-lysine 6-oxidase
Sequence:
MPGVARPPLPLLSLPLLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIALDEEDLRAFRVQQAAVLRQQTAQRSSIKAAGNSSALGRQSTSGQPQRGSRGRWRSRPRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK
Protein: B-cell CLL/lymphoma 9 protein isoform X1 (BCL9 transcription coactivator) (F1R405)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Catenin beta-1
- Pygopus homolog 2
- Catenin, beta 2.
- Lymphoid enhancer-binding factor 1
- Pygopus family PHD finger 1.
- Transcription factor 7-like 1-A
- Transcription factor 7-like 2
- Transcription factor 7-like 1-B
- Transcription factor 7.
Sequence:
MLEVQEERPAAAAATATANTAATGTTGNASGRKERAKERQEEGQDCSSPVATPNTGPRSTRAKATPTATHTHSHTHTHTPSPHQHSTAPASVALGLTSMHSSNPKVRNSPSANTQSSPKSKQEAMVRSPPVMSPSSAAQMDSKLPNQGKQGGAGSQSQPSPCDPKSLSGSHTPKGPQVPIGSMGLKNGQGLSSGNGAKGKIKRERSTSVESFEQRDTGTPSNEGDQKEIGSRAKRLCVGERRLPYSGADWCSGGESDEDDPGFFNCNSADIKPDPGALSASTPTHNTVGAQSTELGSGQKPGSKVVYVFTTEMANKAADAVITGHVDNIITYHMNNISNGKGGKPQLPLNNQIGSLRSDPKQQGVPSQQQPSSHSGDQNHQAASKVAQSGQQQQPQAQPTQPQQPTQGAKPNSLPPDNAPSAGMDSKSLPSSSPQDGAGSHDSSNSAGTPGSQTSNQPPNAGPPQNFPSLDLPKGMDAKLTAQHHQQLAHEIMSSMGDNPEGLSQEQLEHRERSLQTLRDIQRMLFPDDKDMAAMGQGNMGGPPPGAVMMEGGPKKTEQGPLQAMMAQSQSLGKPGGPGGPRPDGPPFGPPGPRDMPFSPDDLGPPPPGPGPMNSHPGGEHGDHMTPEQMAWLKLQQEFYEEKKRKQEQMQHRPMGDMMLHQGGPRGMMRGPPPPYQLNPGEVWGPGGPEPFPDQMNMGPRGMHPHMQRMPGFPGMMNPDMEGGPNAMPRPGMNWPDDMPKMGDGRGFPPGQGMFGGPGGRVERFPNPQSVQEAMFHQGMGDKQGMGMPPGMMMEMNRMMGNQRPMDPGNGGGMMFPRMPGDGPMSPTSRMEFVKGLGQSRGEFGMGPGNLNVNMGPSPQMMPPKMRESQMSLSPEEIMKMRQGGGPMPDGVVPSQRMMQGPPFPDQPHPGDLNMGPNRQFPGIGPQGPGNPRGPRGEPPFGPDQRGGNGRLSHMPPLPPNQGPNSSGPPPGQRNVSRKPSDLNVQSGPANSPNVNPLKSPTLRQVQSPMLGSPSGNLKSPQTPSQLAGMLSGPSAAAVAAAAAIKSPPMMGSAGASPVHMKSPSLPAPSPGWTSSPKPPMQSPGIPQNNKPPLSMTSPNMMGGVEQGGNVPPSAPPSSSSSQPGGMNVPGSLPSSSPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNSMPGMGVNHHPGHPRMMTPNSSGPMPSLSPMGMSAMGSQPLSHGMPNQLPSPNPMGPNMPPHSGPMGPGMMPHGMMMNPVSQDPVMGNNQMMSQGRMGLSHRGQGFPPGQSPPQQVPFPHNGPGHQGGFPHGMGFQGEGGPLGRMGNMPHGPGVEPGMCKPNTPGGQEFNNMPGVFGDSDLHEVMRPGASGIPEFDLSRIIPSEKPSQTLSYFPRGGDAPGGKPPHPSGPPGFAQMQGMMGEGNPRMGLPMQGMGGPPGPGHMGPQDMPMGNPGHNPMRPPGFMGQGMMGPQHRMLSPGQQPGMMGGPGMMQGKERPMYNHPGPVGSPNMMMSLQGMSGPQQTMMMPSQMRPRGMAADMGMGFNPGPGNPGNLMF
Protein: Protein eva-1 homolog B (Protein FAM176B) (Q9NVM1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Schlafen family member 13
Sequence:
MDAPRRDMELLSNSLAAYAHIRANPESFGLYFVLGVCFGLLLTLCLLVISISWAPRPRPRGPAQRRDPRSSTLEPEDDDEDEEDTVTRLGPDDTLPGPELSAEPDGPLNVNVFTSAEELERAQRLEERERILREIWRTGQPDLLGTGTLGPSPTATGTLGRMHYY
Protein: Serine protease inhibitor 88Ea (Serpin 88Ea) (Q9VFC2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Serine protease inhibitor with activity toward trypsin. Negatively regulates the Toll signaling pathway and suppresses the expression of the antifungal peptide drosomycin. Its negative regulation of the Toll signaling pathway also results in the inhibition of the melanization immune response via the phenoloxidase (PPO1) cascade. Essential for unfolding and expansion of the wings after emergence from the pupal case. May regulate the Toll pathway by blocking the proteolysis of the Toll ligand spz.
Subcellular location: Secreted {ECO:0000269|PubMed:19581577}.
Interaction partners:
- RE27547p
Sequence:
MHILSISLMAVLPAIALAGLCGVEPDAGLLDQRLNLYKGQQNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEVVRSAYILEKMNRKERQSKMPLEFSSADRIFFANDLHVTECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSETISIGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDPKTIKQ
Protein: Fatty acid-binding protein, brain (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7) (Fatty acid-binding protein, retina) (R-FABP) (Q05423)
Organism: Gallus gallus (Chicken)
Function: FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Fatty acid binding protein 6
- Transcription factor SOX-10
Sequence:
MVEAFCATWKLADSHNFDEYMKALGVGFAMRQVGNVTKPTVIISSEGDKVVIRTQSTFKNTEISFKLGEEFDETTPDDRNCKSVVTLDGDKLVHVQKWDGKETNFVREIKDGRMVMTLTFGDVVAVRHYEKA
Protein: Coronatine-insensitive protein 1 (COI-1) (F-box/LRR-repeat protein 2) (AtCOI1) (AtFBL2) (O04197)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for jasmonate-regulated plant fertility and defense processes, and for coronatine and/or other elicitors perceptions/responses. Seems to not be required for meiosis. Required for the regulation of some genes induced by wounding, but not for all. Component of SCF(COI1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (probably including the ribulose bisphosphate carboxylase small chain 1B RBCS-1B and the histone deacetylase HDA6). These SCF complexes play crucial roles in regulating response to jasmonate, and their interactions with the COP9 signalosome (CSN) appear to be important for their activity. Interacts with TIFY10A and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor. Involved in the regulation of plant gene expression during plant-pathogen interactions with Pseudomonas syringae and Alternaria brassicicola.
Interaction partners:
- SKP1-like protein 1A
- Protein TIFY 10A
- Cullin-1
- Protein TIFY 7
- Protein TIFY 6B
- Protein TIFY 9
- Cullin-2
- Protein TIFY 10B
- Protein TIFY 11B
- Cullin-like protein 3
Sequence:
MEDPDIKRCKLSCVATVDDVIEQVMTYITDPKDRDSASLVCRRWFKIDSETREHVTMALCYTATPDRLSRRFPNLRSLKLKGKPRAAMFNLIPENWGGYVTPWVTEISNNLRQLKSVHFRRMIVSDLDLDRLAKARADDLETLKLDKCSGFTTDGLLSIVTHCRKIKTLLMEESSFSEKDGKWLHELAQHNTSLEVLNFYMTEFAKISPKDLETIARNCRSLVSVKVGDFEILELVGFFKAAANLEEFCGGSLNEDIGMPEKYMNLVFPRKLCRLGLSYMGPNEMPILFPFAAQIRKLDLLYALLETEDHCTLIQKCPNLEVLETRNVIGDRGLEVLAQYCKQLKRLRIERGADEQGMEDEEGLVSQRGLIALAQGCQELEYMAVYVSDITNESLESIGTYLKNLCDFRLVLLDREERITDLPLDNGVRSLLIGCKKLRRFAFYLRQGGLTDLGLSYIGQYSPNVRWMLLGYVGESDEGLMEFSRGCPNLQKLEMRGCCFSERAIAAAVTKLPSLRYLWVQGYRASMTGQDLMQMARPYWNIELIPSRRVPEVNQQGEIREMEHPAHILAYYSLAGQRTDCPTTVRVLKEPI
Protein: FI11941p (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform D) (Q9VH65)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRTEAAVSCFLLVLHRVCCQSGNDESWLSPDPAWSDLVNDINQPGELCQCPTCPDVSPVAMEDAVALTYFKKFVNLLFQRKRFQYDVMSAVHKRSLLFSLIPSQLDELERVQDARDLDVLLTKILESAEEAPLFNGRSGCSYVRHGFFSLLVDIFKDVIELTQTTEVKFILYATLAIALVVIVHKRFRVGLISIVLGGVFLCGYIQTYLECNRELDIDRMIEVVNHHHEPESSWFGRLLGYIYQASPKTKKIEMIKKSAKISISICMPDQVFFMYMNNIFIKQLEIMIEKVSVTMTKLSSGLSFPYNLLAPVLLVFLVGYTIKLCFKYILSPRAWASLLHKPAPQGTPTIHQSINARAPEGDSISGDNLKMLLNVINVRNVPKESLQRIPDVSGVQELEEKQEAPTTPSKKENLDESDSSSKSKSKSCVAEDEGFTLVDDHEDNNIDNV
Protein: Semaphorin-3F (Semaphorin IV) (Sema IV) (O88632)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Neuropilin-2
- Neuropilin-1
- Plexin-A3
- Plexin-A1
- Plexin-A4
- Plexin-D1
Sequence:
MLVTAFILWASLLTGAWPATPIQDQLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECILSGKDGNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQALPWTQMQVVRGRGSRATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQNPAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRTHPLMYQAVYPLQRRPLVVRTGAPYRLTTVAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQEVEELMLEEVEVFKEPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSKRRSRRQDVRHGNPIRQCRGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPSDRRREIRAEDRFLRTEQGLLLRALQLGDRGLYSCTATENNFKHIVTRVQLHVLGRDAVHAALFPPLAVSVPPPPGTGPPTPPYQELAQLLAQPEVGLIHQYCQGYWRHVPPRPREAPGALRPPELQDQKKPRNRRHHPPDT
Protein: ORF K7 (P88910)
Organism: Human herpesvirus 8 type M
Interaction partners:
Sequence:
MGTLEIKGASLSQFSTGTAQSPWLPLHLWILCSLLAFLPLLVFIGAADCGLIASLLAIYPSWLSARFSVLLFPHWPESCSTKNTARSGALHKPAEQKLRFAQKPCHGNYTVTPCGLLHWIQSPGQL
Protein: Ribonucleoside-diphosphate reductase (EC 1.17.4.1) (Q9I4I1)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Ribonucleoside-diphosphate reductase subunit beta
- Thymidylate kinase
- Vitamin B12-dependent ribonucleotide reductase
- ribonucleoside-diphosphate reductase
- Nucleoside diphosphate kinase
- Adenylate kinase
- Cytidylate kinase
- Guanylate kinase
- UPF0301 protein AlgH
- Pyruvate kinase
Sequence:
MHTDTTRENPQASAPQAADSSQDLAATAPGQLRVIKRNGTVVPYTDDKITVAITKAFLAVEGGTAAASSRIHDTVRRLTEQVTATFKRRMPSGGTIHIEEIQDQVELALMRAGEQKVARDYVIYREARAAERKNAGAASDVAQPHPSIRITRADGSLSPLDMGRLNTIISEACEGLAEVDGALIERETLKNLYDGVAEKDVNTALVMTARTLVEREPNYSYVTARLLMDTLRAEALGFLGVAESATHHEMAELYAKALPAYIEKGAEFELVDAKLKEFDLEKLGKAIDHERDQQFTYLGLQTLYDRYFIHKDGIRFELPQIFFMRVAMGLAIEEKDREARAIEFYNLLSSFDYMSSTPTLFNAGTLRPQLSSCYLTTVPDDLSGIYGAIHDNAMLSKFAGGLGNDWTPVRALGSYIKGTNGKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVFDDGSWTLFSPSDVPDLHDLYGKAFEERYEYYEALASYGKLKLHKVVQAKDLWRKMLSMLFETGHPWLTFKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIAVCNLGSINLVNHIVDGKLDTAKLEKTVKTAVRMLDNVIDINYYSVPQAQNSNFKHRPVGLGIMGFQDALYLQHIPYGSDAAIAFADQSMEAISYYAIQASCDLADERGAYQTFQGSLWSQGILPIDSEKKLIEERGAKYIEVDLSETLDWAPLRERVQKGIRNSNIMAIAPTATIANITGVSQSIEPTYQNLYVKSNLSGEFTVINPYLVRDLKARGLWDPVMVNDLKYYDGSVQQIERIPQDLKDLYATAFEVETRWIVEAASRRQKWIDQAQSLNLYIAGASGKKLDVTYRMAWFRGLKTTYYLRALAATSTEKSTINTGKLNAVSAGGNDGLQAAPAAEPKPAPVPQACSIDNPDCEACQ
Protein: Apidaecin A (C0HKX6)
Organism: Sphecius speciosus (Eastern cicada killer)
Function: Antimicrobial peptide active against many Gram-negative enterobacterial and plant-associated bacterial species. Not active against other bacterial species like H.pylori, P.mirabilis, B.pertussis or N.gonorrhoeae.
Subcellular location: Secreted {ECO:0000269|PubMed:7929322}.
Interaction partners:
Sequence:
NRPTYVPAPPRPPHPRL
Protein: Cadherin domain-containing protein (Q8BNI7)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
MREGTAERGRGQRRPMLLPFLLPLFCPTLSEQIRYKIPEEMPTGSVVGNLAKDLGFSVQELPTRKLRISSEKPYFSVSSESGELLVSSRLDREQICGKKLMCALEFEAVAENPLNFYHLSVELEDINDHTPKFAHTSFELQISESSKPGTRFILGSAHDADIGTNSLQNYQLSPNDHFSLVNKEKSDGSKYPEMILKTALDREKQKLYHLTLTALDFGHPPLNSTAQIQVLVTDANDNPPVFSQDIYRVSLPENVYPGTTVLRVVATDQDEGVNSEITFSFSEAGQVTQFNLDSNTGEITTLHTLDFEEVKEYSLVLEAKDGGGMIAQCTVEIEVLDENDNVPEVLFQSLPDLIMEDAEPGTYIALLKTRDKDSGRNGEVICKLEGGAPFKILTSSGNTYKLVTDGVLDREQNPEYNITIRATDKGDPPLSSSSSVTLHIGDVNDNAPVFTKVSYLVHVAENNPPGASIAQVSASDPDLGANGQVTYYIIASDLEPESLWSYVTINAQSGVLFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRLLVGDRNDNAPRVLYPTLEPDGSALFDMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDDPLPPDPQSELQFYLVVALALISVLFLLAVILAIALRLRHSSSRKAWGCFQSEVVVPPNYSEGTLPYSYNLCAAEFNSLTCNDQLKSGQDLQFADSAGALFPLCNSNESTSHQPNYADMLINQESCEKNDSLLTSIDFHENKDEDACAPVSSIL
Protein: At5g57860 (Ubiquitin-like protein) (Ubiquitin-like superfamily protein) (Q8L8S0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Elongin-C
- RING-box protein 1a
- RING-box protein 1b
- Probable transcription factor PosF21
- F12F1.16 protein
- NEDD8-like protein RUB3
- At2g42780/F7D19.22
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- F18C1.6 protein
- COP9 signalosome complex subunit 4
Sequence:
MAMYIRVKRMKTTYFIQCDPTETVLDVKQKLFALIEQPVNNQRLVLMSTEEVLEDSKSLADQKVENDAVVALTLKKDDNEFEDVNIAQPTDFSLS
Protein: Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (dNC2) (Q9VJQ5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Bifunctional basic transcription factor. Activates transcription of DPE (Downstream Promoter Element) containing promoters while repressing transcription of promoters which contain TATA elements. Together with Chrac-14, promotes nucleosome sliding of ATP-dependent nucelosome remodeling complexes.
Subcellular location: Nucleus {ECO:0000269|PubMed:11062130, ECO:0000269|PubMed:18327268}.
Interaction partners:
- Negative cofactor 2alpha
- Ada2a-containing complex component 2
- D12
- DNA polymerase epsilon subunit 3
- Transcriptional adapter 2A
- Molybdopterin synthase catalytic subunit
- SAGA-associated factor 29kDa
- Ada2a-containing complex component 1
- Transcriptional adaptor 3, isoform C
- histone acetyltransferase
Sequence:
MSNPQEELLPPSAEDDELTLPRASINKIIKELVPTVRVANESRELILNCCSEFIHLISSEANEVCNMRNKKTINAEHVLEALERLGFHDYKQEAEAVLHDCKEVAAKRRRQSTRLENLGIPEEELLRQQQELFAKAREEQAREEQQQWMSMQAAAMVQRPPLADGSVASKPSEDDDDDDDDDY
Protein: EF-hand calcium-binding domain-containing protein 7 (Q8VDY4)
Organism: Mus musculus (Mouse)
Function: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia.
Subcellular location: Cell projection, cilium membrane {ECO:0000269|PubMed:24582806}; Peripheral membrane protein {ECO:0000269|PubMed:24582806}; Cytoplasmic side {ECO:0000269|PubMed:24582806}. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner (PubMed:24582806). {ECO:0000269|PubMed:24582806}.
Interaction partners:
- IQ domain-containing protein E
- Limbin
Sequence:
MASNPGSDAALGTQNPLLSGSPRTKKFPLTEQEVFYMNCRAAYLTIFKSSLENIISKDQLYLALQHAGRNPSQKTINKYWTPQTAKLNFDDFCIILSKEKPTSKAELLKSFKKLDVNDDGAILHSDLQKYLTKRGEKMTQEEVNAVINLADINANGKFDYVKFCKLYMTTSEQCLKTTLERLEADSKLRRQQFGSHMEGSPERGPSPAPKPSPRVIRKNDQETFSSKGDTSHALLSTTRKFKTSVSFTMTMSANSNQDSTLTEPNLKDWQCAQSKGCFFLEEDGEVVSHQYKMHIAQRSVLYLTIKPLYLSQVEGKRCPWLSVDTALYILKKNENPAEPQLMCFTELRNREVFGWTGELEAGIYWLIPSTTGCRLKKETKPVTEEAQLVHRDETGELSLTSEFRSTLSEIFEVIDLDGNGLISLEEYNFFELRTSGEKCDEDAWAVCRENFDTKKNELTRQGFMDLHLMEANDREGDPLDLWVTLHSMGYNKALELTEACPFVINIYAERCKPRIKVVHMEACSGQLEKAICKSVLDRSDAKVMDGYENIIVHTCNYDTWITSIIENKSDNKVIIHINNELSKNCVNNRGLNIFAVEVAPRSTMVCQHVMPLNEQEEWIYCCVYSLVA