Protein: Serine/threonine-protein kinase ATR (EC 2.7.11.1) (D3Z822)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Serine-protein kinase ATM
- ATR interacting protein
- CHK2 checkpoint homolog
- Breast cancer type 1 susceptibility protein homolog
- Cell division cycle 7-related protein kinase
- Telomere length regulation protein TEL2 homolog
- Cellular tumor antigen p53
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- DNA topoisomerase 2-binding protein 1
- Cell cycle checkpoint protein RAD1
Sequence:
MGDHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVALELVKKTDTQPTSVMLLDFIQHIMKSSPLMFVNVNGSQGQNEAKDSCIEFSHWIITRLLRIAATPSCHMLHKKICEVICSLLFLFKSKNPAIFGVLTRELLYLFEDLIYLHKRNAVGDVMEWPVVVSRFLSRLDEHMGCLQPAPLQFMNMQNVEFIEVTLLMVLIHIVPTVFFRRQELLLWQIGCALLEHGSPKIRSLAISLLTELFELGGLPAQPASTFFSLFLELLQHLIGMDADQLKLYEEPLSKLVKTLFPFEAEAYRNIEPVYLNVLLEKLRVMFEDRVLMRLKSDLLKAALCHLLQYFLTFVPAGYESALQVRKVYVTDICRALVDVLGVQTHVGYLLGPFYAALKMESTEIIERIQCQAQQENLRGSNDGVSPKRRRLSSSLSSYKRPSRQSEEINHVDMDKKSILWNVLKQKAESLQISLECGTLKNSVAEALEGITIVLQLTALCTVHCSHQDMDGHNAKDCQHKYKKKPPVVITWMSLDFYTKVLKSCKSLLESVQKHELELVIDSVVRIYDALMYIQVKSSFQDHVLEELCGMLSLPWIYSYSDDNSLKMTTFATNLLRLSQRVWESYSPQAQSQCVFLLTLFPKRIFLDWRTTVYNWALKSSHEVIRTSCVKGFFILLQQENSCNQIPKMLIDRVKDDSHVVKKEFASVLGQLVCTLHGMFYLTSSSVEPFFGPVDLFCKNLKATSQHECSSSQVKASVCKPFLFLLTKNTPSPVKLAFIDNLHHLCKHLDFQEDETEVKAVLGTLLNLMEDPDKDVRIAFSGNIKYILESLNSEDGFIKELFVLRMKEAYTHAQISRSNELKDTLILTTGDIGRAAKGDLIPFALLHLLHCLLSKSASVSGAAYTEIRALVAAKSVKLQNFFSQYKKPICQFLVESLHSSQMTALPSTPCQTAEMRKQHVAHHREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDITSPELMADYLQPKLLGILAFFNMQLLSSSVGIEDKKMALTSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHAYLGPLLSHVIVALLPLIQMQPKETAAIFHYLIIENRVAVQDFLHEIYFLPDHPELEKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIKYATDSETVEPVISQLVTVILKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKDFTFVTGVEDLSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMQSNGPGHQLWKRFPEHVREILEPHLNTRYKSSQKSTDWSGVTKPIYLSKLGNNFAEWSSSWAGYLITKVRDNLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCSQEDQQEVYAEIMAVLKHDDQHAISTQDSASDLCQLSTQTVFSMLDHLTQWARHKFQALNAEKLAQNKPKGVSSVNFEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQKHLGFLQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESIGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSVRLGQLLLSAKKRDTTAFYDTLKLVRAEQIVPLSAASFERGSYQRGYEFIVRLHMLCELEHSLKPLFHKFPGDSCNEDSLNWAARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVELCFPENKSPTESKHMLIHGRATLLVGRFMEETANFESNAIMKKYKDVTLFLPEWEDGHFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLSLWLDFGAKAYEWEKGGRSDRLQMRNDLAKINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILTKAIHMKKSLEKFVGDATRLTDKLLELCNKSVDGSNSTLSMSTHFKMLKKLVEDPTFSEILIPLQSVMIPTLPSILGAHANHDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFQEILLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPPNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM