wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein csyA (Q53U85)
Organism: Aspergillus oryzae (Yellow koji mold)
Interaction partners:
Sequence:
MAPLIHGTSPPEIRNHSDDSLSKRAVSVVGTGAHYPPHELRSDELEKLISAFHDPNDPAVRKTLYVNEKSRIQTRRAAVPFDDPFWSDPKLPDIAECDVLFRKYGVPVAEEAARKALADWNGSFNDLTHVVVVTCTNTANPGLDYMICERLGLRKNVQRTLLHGVGCAGGAAALRTANELLLGAAFQGKPGRALVVACEICMIFFRSMLEDIVKAQEANVAMTLFGDGAGAMVLSNGICPKTSERAPLWNILNCRTTLLEDSASSIQFNIRPHGYDPVITKEVPGQTSAALPSGFQDLISSTPSLYSDKSNFDPSSYDWALHPGGYSIAVLAQNALGITEHHLRKTYEVYRSRGNTSSSTVISVINELAREQGTSESGRDKVIVAAFGPGITMELAVMARPA
Protein: E6-like protein (Expressed protein) (P93019)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ubiquitin domain-containing protein 7SL RNA1
- Early nodulin-like protein 1
- Cytochrome P450 71B22
- Large ribosomal subunit protein eL6y
- Probable protein phosphatase 2C 2
- Large ribosomal subunit protein eL6x
- Putative fasciclin-like arabinogalactan protein 20
- Large ribosomal subunit protein eL42z/eL42y
- Fasciclin-like arabinogalactan protein 19
- Probable glucan endo-1,3-beta-glucosidase A6
Sequence:
MAFSTSSCLFFFLLTLVLFSTQISARNSYSFGKFQREDPKEQNPNNLVPIETNEKKEPDDQNPAFIPQSENGYGLYGHETTDNNNEELNNNKYEDNVNYDDSFSTPSLSETAQTQESYKNYKESYPKTTEIYDNNKDTSYYENSNAYGTDKRDNDINDPYKGYSNKDTSYYENPNTYGTEKREKEPAYRGYNNNVERQGMSDTRYMANGKYYYDLDDDRNHGRFYQNHYYNYKPTGYNEKKSNFKNPYDSNQQSEMLGEEQGDQITP
Protein: TCDD inducible poly(ADP-ribose) polymerase (F1N973)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Aryl hydrocarbon receptor repressor
Sequence:
MDTEAKPACVAPQARCPGMKCPPSEDFPPQIRLSEKIPPVKPCFKKKQQVQKRLDTQTLRALRPIFTSLLGSGTLDRVFVPRGQGGGHSDLCEPAVKKTLELSTSCTQPESNVTVLVPTAPDVQSQLLGAHPAPGHPEQEVQTGEQSFSSETAPGAAADTSNESFQDRPLHPPSSDGAACPLFPSKLLKSYATGLFQENSCPMQYTLNSSNKFSAGIFQDKSEEASLDLVFELLNQLQYHTHQEDGIEICVDFLQGACVYGSDCPKHHTVLPYHWQVRRTATQSWQSVSNDSQEHLERLYCNPDNDRIKVKYRGHEFWVDLNAMKLYETVEFDQMRRLSTPSCPSSSSNYYTVWKYFCRDHFVWREYSEPVVRLIEEASCRGLKEVRFVTWHNQYILNIKDGFQQNACFRREIKRRPLLRSCVVLMPFLQTLGGNSPVPSPSAEPLSSHVLSPTAVTSPNFYPETWISMDPSQDFIQVPVLKEDKSYRTIYNLFHKTVPETKYKILKILRVQNQFLWEKYKRKKEYMSKKMTGLDRIMNERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFARKASYSHNFSKRSPKGVHYMFLAKVLTGRYTVGNHTMRRPPPVNPGSITSDLYDSCVDNYFEPQIFVIFNDDQSYPYFIIQYEEVSNTVSI
Protein: Mitogen-activated protein kinase 18 (AtMPK18) (MAP kinase 18) (EC 2.7.11.24) (Q9C5C0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitogen-activated protein kinase (MAPK) that is specifically regulated by PHS1 and MAPKKK20 and mediates signaling that regulates cortical microtubule functions, maybe through regulation of microtubule dynamic instability.
Subcellular location: Nucleus {ECO:0000269|PubMed:28848569}. Cytoplasm {ECO:0000269|PubMed:19392697, ECO:0000269|PubMed:28848569}.
Interaction partners:
- Protein-tyrosine-phosphatase PTP1
- Dual specificity protein phosphatase 1B
- Mitogen-activated protein kinase kinase kinase 20
- Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein
Sequence:
MQQNQVKKGTKEMEFFTEYGDANRYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRALKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVFWTDYVATRWYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETISGVRNDKARKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADPYFKGLSKIEREPSSQQISKMEFEFERRRLTKDDIRELIYREILEYHPQLLKDYMSGSEGSNFVYPSAIGHLRQQFTYLEENSSRNGPVIPLERKHASLPRSTVHSTVVHSTSQPNLGATDSRRVSFEPSKNGASSAGHPSTSAYPTKSIGPPPRVPPSGRPGRVVESSVSYENGRNLKEAYFRSAVSSPHCYFRPNTMTNPENRNIEASSFPPKPQNPVHQFSPTEPPAATTNQADVETMNHPNPYFQPQLPKTDQLNNNTHMAIDAKLLQAQSQFGPAGAAAVAVAAHRNIGTISYSAAS
Protein: Curved DNA-binding protein (P36659)
Organism: Escherichia coli (strain K12)
Function: DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
Subcellular location: Cytoplasm, nucleoid {ECO:0000269|PubMed:10947847, ECO:0000269|PubMed:8302830}.
Interaction partners:
- Chaperone modulatory protein CbpM
- Chaperone protein DnaK
- Protein GrpE
- Chaperone protein HscC
- Chaperone protein HscA
- Co-chaperone protein DjlA
- Chaperone protein HtpG
- Right origin-binding protein
- Probable pyruvate-flavodoxin oxidoreductase
- Uncharacterized chaperone protein YegD
Sequence:
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
Protein: Homeobox protein MIXL1 (Homeodomain protein MIX) (hMix) (MIX1 homeobox-like protein 1) (Mix.1 homeobox-like protein) (Q9H2W2)
Organism: Homo sapiens (Human)
Function: Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:17303500}.
Interaction partners:
- Forkhead box protein H1
- Eomesodermin homolog
- Transcription factor SOX-17
- Hepatocyte nuclear factor 3-beta
- T-box transcription factor T
- Homeobox protein NANOG
- Mothers against decapentaplegic homolog 2
Sequence:
MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF
Protein: Teashirt zinc finger homeobox 3 L homeolog (Tsh3) (A0SNQ7)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MDSDSHVSETSDRMGDFESCSIKNEEESKESLAPLEDSNVSDSLEQMKAVYNNFLSNSYWSSLSLNLHQSTSEKNNASSSSSSSSSSSCGSGSFDWHQTAIAKTLQQVSQSRVLPEPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAVYDTLVELTVHMNETGHYRDDNHETDNKNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIVPASRKKLSLELELSNSPDSTGGTQKATNPDVNDALQKNSNPYITPNNRYGHQNGASYAWHFEARKSQILKCMECGSSHDTLQELTTHMMVTGHFIKVTNSALKKGKSVLEAPATPTSLIDEKVQSVPLAATTFTPPLNNSSCLSPKLNVEIKKEVDKGISDDKIKDKDKTNEEEDKFDVSSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKATPLKPMYGSSELISPTKNQPIMSPPSSQTSPVPKTNFHAMEELVKKVTEKVAKVEEKMKEPEGKFSPIKRTTPSPSGSEISETLKGDVSNEVTFKSQQNSPIPQKDSRKDSPSVEPVENGKDHAKSIIGSLSSSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPIQAKKIDHLDRYFYHVNNDQPIDLTKGKSDKNCSLASALLSSTSTSTASSSSTVTTAKTSAVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPTSISEKSDIEGTTIEEPEENTPAQKRKGRQSNWNPQHLLILQAQFAASLRQTSEGKYVMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFRIRDLSKLSSEQISNQIAQTKSPSEKMVASSPEEENGTSYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLYVTELEKQ
Protein: Uncharacterized protein C14C4.10c (O13717)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Nuclear movement protein nudc
Sequence:
MELELDLLTGLQLLSEYCPRVTPNAPPRRASVAVIIAFKESQDFSNPKWPQCIPITSVPYVLLIQRSFRDTDRWSGHMALPGGTRSLTDKSDIQTAHRETLEEVGIDLRKEHAHFVGALDERVITSNWGQFPLLLLSSFVFILPYMPSLRLQESEVFSAQWYPLADLLLPECQTRIQIDSSRALKKTYPRFIKTLFHLAVGNLMYSAIRLEFDPSSATYSLPPYQRPFLRGITHSIFVDLFIFLSPSSARHCLCWSLPYFQHYDLRFIASFFTQFYRLRLHQVYPRGNWVFTCLNGYYPYLKLTLLVGFLFRLFLVYLLFLIISAYYKS
Protein: Tuberous sclerosis 2 isoform D (X5D7Q2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
Protein: LIM and senescent cell antigen-like-containing domain protein (A0A8I6GA69)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|PIRNR:PIRNR038003}. Cell membrane {ECO:0000256|PIRNR:PIRNR038003}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR038003}.
Interaction partners:
Sequence:
MLSALSVNKLTISVLPFVCFSNMANALASATCERCKGGFDPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVSCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSETLGRK
Protein: Transcriptional factor SWI5 (P08153)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Determines the mother-cell-specific transcription of the HO endonuclease gene that is responsible for the initiation of mating-type switching in yeast. Recognizes a specific sequence in the promoter of the HO gene. Activates EGT2 transcription in a concentration-dependent manner. Synthesized during G2 and early mitosis.
Subcellular location: Nucleus {ECO:0000269|PubMed:1652372}. Cytoplasm {ECO:0000269|PubMed:1652372}. Note=Nuclear in G1, cytoplasmic in S, G2 and M cell cycle phases.
Interaction partners:
- APC/C activator protein CDH1
- Cyclin-dependent kinase 1
- G2/mitotic-specific cyclin-2
- Tyrosine-protein phosphatase CDC14
- G2/mitotic-specific cyclin-1
- Endochitinase
- Transcriptional regulatory protein ASH1
- Protein SIC1
- Fork head protein homolog 2
- Nuclear division defective protein 1
Sequence:
MDTSNSWFDASKVQSLNFDLQTNSYYSNARGSDPSSYAIEGEYKTLATDDLGNILNLNYGETNEVIMNEINDLNLPLGPLSDEKSVKVSTFSELIGNDWQSMNFDLENNSREVTLNATSLLNENRLNQDSGMTVYQKTMSDKPHDEKKISMADNLLSTINKSEINKGFDRNLGELLLQQQQELREQLRAQQEANKKLELELKQTQYKQQQLQATLENSDGPQFLSPKRKISPASENVEDVYANSLSPMISPPMSNTSFTGSPSRRNNRQKYCLQRKNSSGTVGPLCFQELNEGFNDSLISPKKIRSNPNENLSSKTKFITPFTPKSRVSSATSNSANITPNNLRLDFKINVEDQESEYSEKPLGLGIELLGKPGPSPTKSVSLKSASVDIMPTIPGSVNNTPSVNKVSLSSSYIDQYTPRGKQLHFSSISENALGINAATPHLKPPSQQARHREGVFNDLDPNVLTKNTDNEGDDNEENEPESRFVISETPSPVLKSQSKYEGRSPQFGTHIKEINTYTTNSPSKITRKLTTLPRGSIDKYVKEMPDKTFECLFPGCTKTFKRRYNIRSHIQTHLEDRPYSCDHPGCDKAFVRNHDLIRHKKSHQEKAYACPCGKKFNREDALVVHRSRMICSGGKKYENVVIKRSPRKRGRPRKDGTSSVSSSPIKENINKDHNGQLMFKLEDQLRRERSYDGNGTGIMVSPMKTNQR
Protein: ABC transporter G family member 2 (ABC transporter ABCG.2) (Q9NGP5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Required for endocytosis and endosomal pH regulation.
Subcellular location: Endosome membrane {ECO:0000269|PubMed:11719559}; Multi-pass membrane protein {ECO:0000269|PubMed:11719559}. Note=Associated with the endosome/lysosome system.
Interaction partners:
- Protein rtoA
Sequence:
MAPPEIGNDEIPLQEFGQKSFAADNTIGGMQSISYDNSGAPMGLYKEKKGMYVTARNLSMSIGTEKKGDKRNILSDLNFFLKPGSMVLILGSPGCGKTSVMKALANQLHSETVSGSLLFNGKAANKSTHHRDVAYVVQGDHHMAPFTVRETFKFSADLQMSEGTSEEEKNARVDYILKTLDLTRQQDTVVGNEFLRGVSGGQKKRVTIGVEMVKDAGLFLMDEPSTGLDSTTTLELMKHFRELSNVNQVSSLVALLQPGVEVTKLFDFLMIMNAGHMVYFGPMSDAISYFEGLGFKLPKHHNPAEFFQEIVDEPELYFEGEGEPPLRGAEEFANAYKNSAMFQSIVNDLDNTQPDLTFCKDSSHLPKYPTPLSYQIRLASIRAFKMLISSQVAVRMRIIKSIVMGLILGSLFYGLDLNQTDGNNRSGLIFFSLLFIVFSGMGAIAILFEQREVFYIQKDGKYYKTFAFFLSLIFSEIPIALLETVVFCVLVYWMCGLQANAEKFIYFLLMNFVGDLAFQSFFKMVSAFAPNATLASVIAPAALAPFILFSGFMAPKRSIGGWWIWIYWISPIKYAFEGLMSNEHHGLIYSCDDSETIPPRNTPNFELPYPRGSGNSSICQITRGDQFLDQLGMPQNNWFKWIDLLIVFAFGALFSFGMYFFLKNVHVDHRASDPKNDKRSKKASKRSKKIKDSKVDIKENRMVKAQKEIPIGCYMQWKDLVYEVDVKKDGKNQRLRLLNEINGYVKPGMLLALMGPSGAGKSTLLDVLANRKTGGHTKGQILINGQERTKYFTRLSAYVEQFDVLPPTQTVKEAILFSAKTRLPSDMPNEEKIKFVENIIETLNLLKIQNKQIGHGEEGLSLSQRKRVNIGVELASDPQLLFLDEPTSGLDSSAALKVMNLIKKIASSGRSIICTIHQPSTSIFKQFDHLLLLKRGGETVYFGPTGDKSADLLGYFENHGLICDPLKNPADFILDVTDDVIETTLDGKPHQFHPVQQYKESQLNSDLLAKIDAGVMPVGTPVPEFHGVYSSSYQTQFVELGKRSWLAQVRRVQNIRTRLMRSLFLGVVLGTLFVRMEETQENIYNRVSILFFSLMFGGMSGMSSIPIVNMERGVFYREQASGMYSIPIYLFTFIVTDLPWVFLSAIIYTVPMYFISGLRLDPNGAPFFYHSFISFTTYFNFSMLAMVFATVLPTDEIAHALGGVALSISSLFAGFMIPPASIAKGWHWFYQLDPTTYPLAIVMINEFQDLEFHCTSSESVTIPNVLTVNGTYIDVGPICPITNGNQILQRYEMKPEDKYKFLAVIFGYSVFFFICIFIALKFIRHQTK
Protein: N-acetylmuramoyl-L-alanine amidase AmiB (EC 3.5.1.28) (P26365)
Organism: Escherichia coli (strain K12)
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors.
Subcellular location: Periplasm {ECO:0000250}.
Interaction partners:
- Murein hydrolase activator EnvC
- Murein hydrolase activator NlpD
- N-acetylmuramoyl-L-alanine amidase AmiC
- tRNA dimethylallyltransferase
- DNA mismatch repair protein MutL
- N-acetylmuramoyl-L-alanine amidase AmiA
- tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
- Cell division protein FtsX
- Uncharacterized lipoprotein YgeR
- Bifunctional NAD
Sequence:
MMYRIRNWLVATLLLLCTPVGAATLSDIQVSNGNQQARITLSFIGDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDLTENGKTEAVKRQNGSNYTVVFTINADVPPPPPPPPVVAKRVETPAVVAPRVSEPARNPFKTESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNVTIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRSATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQSDPYLSQAVLDLQFGHSQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEERLLASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN
Protein: Ribose-5-phosphate isomerase A (EC 5.3.1.6) (Phosphoriboisomerase A) (PRI) (P0A7Z0)
Organism: Escherichia coli (strain K12)
Function: Involved in the first step of the non-oxidative branch of the pentose phosphate pathway. It catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. Can also act on D-ribose-5-diphosphate and D-ribose-5-triphosphate as substrate.
Interaction partners:
- Ribose-5-phosphate isomerase B
- Ribulose-phosphate 3-epimerase
- Transketolase 1
- 6-phosphogluconate dehydrogenase, decarboxylating
- Transketolase 2
- Phosphopentomutase
- Ribose-phosphate pyrophosphokinase
- Ribokinase
- Uncharacterized protein YhfW
- Phosphoglucomutase
Sequence:
MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK
Protein: Transcription factor TGA5 (Ocs element-binding factor 5) (OBF5) (bZIP transcription factor 26) (AtbZIP26) (Q39163)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. May be involved in the induction of the systemic acquired resistance (SAR) via its interaction with NPR1. Could also bind to the Hex-motif (5'-TGACGTGG-3') another cis-acting element found in plant histone promoters.
Subcellular location: Nucleus.
Interaction partners:
- Regulatory protein NPR1
- Regulatory protein NPR3
- Regulatory protein NPR4
- Dof zinc finger protein DOF3.4
- Protein NIM1-INTERACTING 1
- DEAD-box ATP-dependent RNA helicase 36
- Protein NUCLEOLAR FACTOR 1
- Pre-mRNA-splicing factor SYF2
- Nucleolar-like protein
- Regulatory protein NPR5
Sequence:
MGDTSPRTSVSTDGDTDHNNLMFDEGHLGIGASDSSDRSKSKMDQKTLRRLAQNREAARKSRLRKKAYVQQLENSRLKLTQLEQELQRARQQGVFISSSGDQAHSTAGDGAMAFDVEYRRWQEDKNRQMKELSSAIDSHATDSELRIIVDGVIAHYEELYRIKGNAAKSDVFHLLSGMWKTPAERCFLWLGGFRSSELLKLIASQLEPLTEQQSLDINNLQQSSQQAEDALSQGMDNLQQSLADTLSSGTLGSSSSGNVASYMGQMAMAMGKLGTLEGFIRQADNLRLQTYQQMVRLLTTRQSARALLAVHNYTLRLRALSSLWLARPRE
Protein: Protein TILLER ANGLE CONTROL 1 (Q0J059)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in the regulation of tiller growth angle. Promotes horizontal shoot growth. TAC1 and LAZY1 play opposite functions in the regulation of tiller growth angle.
Interaction partners:
Sequence:
MALKVFNWLNRKKHSNVEYCTINENKAMEEKEDSLRASVTEQDTEALLLRDVLINGILAIGTLGHNVNSLCPESCIEQDEPIIMCDEKVEQEKCEEEKAEAKQDTPVTAPSEPASALEPAKMHSSSMKEDNFMCFVKEEILMHGMEVEDVPNIQERPLLMLEKVEKVRTTLADLFAAEAFSSSDAEDKCYPKIVIVAGASTSKPTSCMEKMHHKKPTKPTSKPLKATRKLSRVMRKMLGKKIHPEQLNGRSNAEGPVTA
Protein: Cornifin-B (14.9 kDa pancornulin) (Small proline-rich protein IB) (SPR-IB) (P22528)
Organism: Homo sapiens (Human)
Function: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Subcellular location: Cytoplasm.
Interaction partners:
- Cornifin-A
- Involucrin
- Small proline-rich protein 2A
- Protein-glutamine gamma-glutamyltransferase K
- Small proline-rich protein 2D
- Small proline-rich protein 2E
- Loricrin
- Small proline-rich protein 2G
- Small proline-rich protein 2F
- Small proline-rich protein 3
Sequence:
MSSQQQKQPCTPPPQLQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCHPKVPEPCQPKVPEPCHPKVPEPCPSIVTPAPAQQKTKQK
Protein: Insulin-like peptide 2 (dILP2) (Insulin-related peptide 2) [Cleaved into: Insulin-like peptide 2 A chain; Insulin-like peptide 2 B chain] (Q9VT51)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in regulating body size by increasing cell size and cell number of individual organs. Probably mediates its growth effects by acting as a ligand for the insulin receptor and transducing a signal via the Chico/PI3K/Akt(PKB) pathway.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Insulin-like peptide 5
- Insulin-like peptide 3
- Insulin-like peptide 1
- Neural/ectodermal development factor IMP-L2
- Insulin-like peptide 6
- Insulin-like receptor
- Insulin-like peptide 7
- Insulin-like peptide 4
- Insulin receptor substrate 1
- Death-associated inhibitor of apoptosis 2
Sequence:
MSKPLSFISMVAVILLASSTVKLAQGTLCSEKLNEVLSMVCEEYNPVIPHKRAMPGADSDLDALNPLQFVQEFEEEDNSISEPLRSALFPGSYLGGVLNSLAEVRRRTRQRQGIVERCCKKSCDMKALREYCSVVRN
Protein: Large ribosomal subunit protein eL21A (60S ribosomal protein L21-A) (Q9UUC1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein eL18A
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein eL22
- Large ribosomal subunit protein eL43A
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein uL15A
- Large ribosomal subunit protein eL33B
- Large ribosomal subunit protein eL29
Sequence:
MPHSYGIRARTRYTFQRGFREHGQIRLSTYLKTYKVGDIVDIKVNGAVQKGMPHKYYHGKTGVVYNVTQSSVGVLIYKVVGNRYMEKRVNVRIEHVKHSKCRQDFLDRVKANEAKRKEAKAQGKTVQLRRQPAPPAKAHFVSTENNEPVTLHPVAYDTTI
Protein: T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (A8MUH3)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MEQGKGLAVLILAIILLQGTLAQSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGKMIGFLTEDKKKWNLGSNAKDPRGMYQCKGSQNKSKPLQVYYRTSDKQTLLPNDQLYQPLKDREDDQYSHLQGNQLRRN
Protein: Transcriptional regulator AhyR/AsaR family (Q5H3E9)
Organism: Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Interaction partners:
- Transcriptional regulator luxR/uhpA family
- Sensory/regulatory protein RpfC
- histidine kinase
Sequence:
MAKVLGFPCWLSLVGNHRYRGITMFEILASLGRDLQASQTVNSCLDRVFRDVCALGFQSLVYDYAPVPLSMEGALITPTVFMQRNAPGDMQHVWCEHGYYQHDPVQQRATRRNTPFVWSYRTDGDCAGVEYVGGQHRQVTRYLCDSGMGTGVTVPLHLPGGAFATFSAAIDAVAAEALRLAESQLLPFLLLAHAFQARAQELLDPQERRCHHIPLTRRERECLQYSAKGLTSKRIAAALNRSTATVNLHLNSAARKLGARNRVEAVVRGMHYRLLEP
Protein: Small ribosomal subunit protein eS4 (40S ribosomal protein S4, X isoform) (P62703)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62701}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62701}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000250|UniProtKB:P62701}.
Interaction partners:
- Ubiquitin-like protein FUBI
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS2
- FAU ubiquitin like and ribosomal protein S30 fusion like 2
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein uS19
- Ubiquitin-ribosomal protein eL40 fusion protein
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein eL18
Sequence:
MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG
Protein: Protein unc-50 homolog (Periodontal ligament-specific protein 22) (PDLs22) (Protein GMH1 homolog) (hGMH1) (Uncoordinated-like protein) (Q53HI1)
Organism: Homo sapiens (Human)
Function: Involved in the cell surface expression of neuronal nicotinic receptors (By similarity). Binds RNA (By similarity).
Subcellular location: Nucleus inner membrane {ECO:0000250|UniProtKB:O55227}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O55227}. Golgi apparatus membrane {ECO:0000269|PubMed:12808035}; Multi-pass membrane protein {ECO:0000269|PubMed:12808035}.
Interaction partners:
- Protein RIC-3
Sequence:
MLPSTSVNSLVQGNGVLNSRDAARHTAGAKRYKYLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKLLLWVVLIDCVGVGLLIATLMWFISNKYLVKRQSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINHVILTDTFIGYLVGNTLWLVAVGYYIYVTFLGYSALPFLKNTVILLYPFAPLILLYGLSLALGWNFTHTLCSFYKYRVK