wanglab/gogpt-training-data huggingface dataset:
Protein: Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (CPEB) (CPEB-1) (P0C279)
Organism: Rattus norvegicus (Rat)
Function: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation. Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses. Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation. Induces the assembly of stress granules in the absence of stress. Required for cell cycle progression, specifically for prophase entry.
Subcellular location: Cytoplasm {ECO:0000250}. Synapse {ECO:0000250}. Cytoplasm, P-body {ECO:0000250}. Cytoplasmic granule {ECO:0000250}. Membrane {ECO:0000250}. Postsynaptic density {ECO:0000250}. Note=Localizes in synaptosomes at dendritic synapses of neurons. Strongly enriched in postsynaptic density fractions. Transported into dendrites in a microtubule-dependent fashion and colocalizes in mRNA-containing particles with TACC3, dynein and kinesin (By similarity). Membrane-associated (By similarity). Colocalizes at excitatory synapses with members of the polyadenylation and translation complex factors (CPSF, APLP1, TACC3, AURKA, SYP, etc.) including CPE-containing RNAs (By similarity). In P-bodies and stress granules (By similarity). Recruited to stress granules (SGs) upon arsenite treatment (By similarity). {ECO:0000250}.
Interaction partners:
- Poly
- Symplekin
- Aurora kinase A
- Fragile X messenger ribonucleoprotein 1
- Cyclin-dependent kinase 1
- Serine/threonine-protein kinase PLK1
- Polyadenylate-binding protein 1
- Fxr2 protein
- RNA-binding protein FXR1
- Double-stranded RNA-binding protein Staufen homolog 1
Sequence:
MAFSLEEESGRIKDCWDNQEVPALSTCSNANIFRRINAILDDSLDFSKVCTTPINRGIHDQLPDFQDSEEAITSRMLFPTSAQESPRGLPDANGLCLGLQSLSLTGWDRPWSTQDSDSSAQSNTQSVLSMLQNPLGNVLGKTPLSFLSLDPLGSDLDKFPAPSVRGSRLDTRPILDSRSSSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSMTGNGPRDPLKMGVGSRMDQEQAALAAVAPSPTSAPKRWPGTSVWPSWDLLGAPKDPFSIEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFELEKSVRALLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVWSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVTAAFVEIKTTKFTKKVQIDPYLEDSLCLICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKN
Protein: Na(+)/H(+) antiporter (Q72IM4)
Organism: Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MHGAEHLLEIFYLLLAAQVMAFIFKRLNQPVVIGEVLAGVLVGPALLGLVHEGEILEFLAELGAVFLLFMVGLETRLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEIGFETLPALFLGTALVATSVGITARVLQELGVLSRPYSRIILGAAVIDDVLGLIVLAVVNGVAETGQVEVGAITRLIVLSVVFVGLAVFLSTLIARLPLERLPVGSPLGFALALGVGMAALAASIGLAPIVGAFLGGMLLSEVREKYRLEEPIFAIESFLAPIFFAMVGVRLELSALASPVVLVAGTVVTVIAILGKVLGGFLGALTQGVRSALTVGVGMAPRGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE
Protein: Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (Q7K0E6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Methionine--tRNA ligase, cytoplasmic
- Probable glutamine--tRNA ligase
- Isoleucine--tRNA ligase, cytoplasmic
- Probable arginine--tRNA ligase, cytoplasmic
- leucine--tRNA ligase
- Lysine--tRNA ligase
- Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2
- Tyrosine--tRNA ligase
- Glutamyl-tRNA
Sequence:
MVEDKEQVANGEQVSKKGAKKLAKAAKKAEQKAENASTAAANNAGGDSAEDHAAGRYGLSEMIQSKDKRSERNFVPVSELSGQVGKGLVWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNIPKESIIDIQAKPVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDAEGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAASEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFVGLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPLILQFADGVAMLREAGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTMPDPNNPVYSNSYDMFMRGEEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCPPHAGGGIGMERVVMLYLGLDNIRKTSMFPRDPKRLTP
Protein: Epigen (Epithelial mitogen) (EPG) (Q6UW88)
Organism: Homo sapiens (Human)
Function: Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Subcellular location: [Isoform 1]: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 4]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 5]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 6]: Secreted {ECO:0000305}.
Interaction partners:
- Epidermal growth factor receptor
- Probetacellulin
- Amphiregulin
- Pro-epidermal growth factor
- Proheparin-binding EGF-like growth factor
- Proepiregulin
- Receptor tyrosine-protein kinase erbB-4
- Protransforming growth factor alpha
Sequence:
MALGVPISVYLLFNAMTALTEEAAVTVTPPITAQQGNWTVNKTEADNIEGPIALKFSHLCLEDHNSYCINGACAFHHELEKAICRCFTGYTGERCEHLTLTSYAVDSYEKYIAIGIGVGLLLSGFLVIFYCYIRKRCLKLKSPYNVCSGERRPL
Protein: DNA-directed RNA polymerase subunit Rpo6 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit K) (Q97ZJ9)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00192}.
Interaction partners:
- DNA-directed RNA polymerase subunit Rpo3
- DNA-directed RNA polymerase subunit Rpo11
- DNA-directed RNA polymerase subunit Rpo10
- DNA-directed RNA polymerase subunit Rpo1C
- DNA-directed RNA polymerase subunit Rpo5
- DNA-directed RNA polymerase subunit Rpo12
- DNA-directed RNA polymerase subunit Rpo7
- DNA-directed RNA polymerase subunit Rpo1N
- DNA-directed RNA polymerase, subunit B''
- DNA-directed RNA polymerase subunit Rpo2
Sequence:
MGLERDEILSQDLHFNEVFISLWQNRLTRYEIARVISARALQLAMGAPALIDINNLSSTDVISIAEEEFRRGVLPITIRRRLPNGKIILLSLRKS
Protein: Uncharacterized protein YHR177W (P38867)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
Sequence:
MMDISPTCYGYIDDEQDLALVFQGVFNGNLRCIERRPYDAEKVELVNPGNIFVFNEEKSGIKRWTDGFSWSPSRISGKFLVYREYNRLGSTHDLPLHNVPEYNIFERAHRKYFYTGLLKKTFSLKFNMDPTDSTKLETFHLIAYYTEKDIHQGSLRRPSENPFFHKFRPSQKLLDALQKVAVGNGRSNPSKNNERGRTKAHNYKTRRSLSSSPSYCDLLSNYNNHPGNIPVRTAVQLPLTTFNNAPREMHQQQHRQQQQYLLPIDEQNKLPLPYMQHQPQPIGVYNPNYQPGLRRTVSQPMIFCNTYNTLPQQPTAAPYERRGVSPSVIYSSNTLSPIPYQNIDPYSSRSGPECNHSKAPIAPTMMPPVHHILVHDYRQPKPVTDSINPPNVNITTSTTNKNLDGIYILPAPRMNPPAQTQYQMIHAPDSMQHPPTFSKNNTSSNPKSHQYSK
Protein: Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) (Succinyl-coenzyme A synthetase alpha subunit 1) (Q94522)
Organism: Drosophila melanogaster (Fruit fly)
Function: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03222}.
Interaction partners:
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- ATP-citrate synthase
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- RH44771p
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Probable 2-oxoadipate dehydrogenase complex component E1 homolog
Sequence:
MAASMRALLKVRDGFVAGVRCNSQYNKTRGNLKLNGDSRVICQGFTGKQGTFHSQQALEYGTKLVGGISPKKGGTQHLGLPVFASVAEAKKATDPHATVIYVPPPGAAAAIIEALEAEIPLIVCITEGVPQHDMVKVKHALISQSKSRLVGPNCPGIIAPEQCKIGIMPGHIHKRGKIGVVSRSGTLTYEAVHQTTEVGLGQTLCVGIGGDPFNGTDFIDCLEVFLKDPETKGIILIGEIGGVAEEKAADYLTEYNSGIKAKPVVSFIAGVSAPPGRRMGHAGAIISGGKGGANDKIAALEKAGVIVTRSPAKMGHELFKEMKRLELV
Protein: Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (P28028)
Organism: Mus musculus (Mouse)
Function: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. May play a role in the postsynaptic responses of hippocampal neurons.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. {ECO:0000250}.
Interaction partners:
- RAF proto-oncogene serine/threonine-protein kinase
- Dual specificity mitogen-activated protein kinase kinase 1
- GTPase HRas
- GTPase NRas
- GTPase KRas
- 14-3-3 protein zeta/delta
- 14-3-3 protein theta
- Dual specificity mitogen-activated protein kinase kinase 2
- Serine/threonine-protein kinase A-Raf
- 14-3-3 protein epsilon
Sequence:
MAALSGGGGSSSGGGGGGGGGGGGGDGGGGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLVFQTPTDASRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPVPQEEASFPETALPSGSSSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSSSEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH
Protein: Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) (Q96QD8)
Organism: Homo sapiens (Human)
Function: Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The trasnport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier. May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta (By similarity). Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate (By similarity). Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9JHE5}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9JHE5}. Note=Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes. Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal. {ECO:0000250|UniProtKB:Q9JHE5}.
Interaction partners:
- Sodium-coupled neutral amino acid symporter 1
- Neutral amino acid transporter B
- Large neutral amino acids transporter small subunit 1
- Sodium channel protein type 11 subunit alpha
- Pre-B-cell leukemia transcription factor 2
- Serotonin N-acetyltransferase
- Amino acid transporter heavy chain SLC3A2
Sequence:
MKKAEMGRFSISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHNAPGGGH
Protein: Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form] (P68035)
Organism: Rattus norvegicus (Rat)
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Troponin T, cardiac muscle
- Troponin I, cardiac muscle
- Myosin-6
- Tropomyosin alpha-1 chain
- Myosin-7
- Myosin light chain 3
- Myosin light chain 4
- Tropomyosin beta chain
- Tropomyosin alpha-4 chain
- Tropomyosin 3
Sequence:
MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
Protein: Large ribosomal subunit protein eL34 (60S ribosomal protein L34) (Q9VBH8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL19
- Ubiquitin-ribosomal protein eL40 fusion protein
- 40S ribosomal protein S24
- GEO07453p1
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein eL6
- 60S ribosomal protein L27
Sequence:
MVQRLTLRRRLSYNTRSNKRRIVRTPGGRLVYQYVKKNPTVPRCGQCKEKLHGITPSRPSERPRMSKRLKTVSRTYGGVLCHSCLRERIVRAFLIEEQKIVKALKSQREALVKPVKKVVEKKPVKAAAKKPAGKAAGKPGAKVAGKKPAPKGAPKGVVKSKK
Protein: Afg3l2 protein (Q5BJM6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARMIDDEVRILISEAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFTEKSTYEEFVEGTGSLDEDTSLPEGLQDWNKEREKEKKEKKEKEEPVNEKVVS
Protein: Hydroxyproline O-galactosyltransferase GALT3 (EC 2.4.1.-) (Beta-1,3-galactosyltransferase 16) (Q9ASW1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses hydroxyproline O-galactosyltransferase activity. Transfers galactose from UDP-galactose to hydroxyproline residues in the arabinogalactan proteins (AGPs). Is specific for AGPs containing non-contiguous peptidyl hydroxyproline residues. Utilizes UDP-galactose solely as sugar donor. The addition of galactose onto the peptidyl hydroxyproline residues in AGP core proteins represents the first committed step in arabinogalactan polysaccharide addition. AGP glycans play essential roles in both vegetative and reproductive plant growth.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:26690932}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Beta-1,6-galactosyltransferase GALT31A
- Beta-1,6-galactosyltransferase GALT29A
- Beta-glucuronosyltransferase GlcAT14C
- Beta-glucuronosyltransferase GlcAT14A
- Beta-glucuronosyltransferase GlcAT14B
- Fucosyltransferase 6
- Probable fucosyltransferase 4
- Beta-arabinofuranosyltransferase RAY1
- Probable xyloglucan galactosyltransferase GT19
- Probable xyloglucan galactosyltransferase GT14
Sequence:
MKQFMSVVRFKFGFTSVRMRDWSVGVSIMVLTLIFIIRYEQSDHTHTVDDSSIEGESVHEPAKKPHFMTLEDLDYLFSNKSFFGEEEVSNGMLVWSRMRPFLERPDALPETAQGIEEATLAMKGLVLEINREKRAYSSGMVSKEIRRICPDFVTAFDKDLSGLSHVLLELPCGLIEDSSITLVGIPDEHSSSFQIQLVGSGLSGETRRPIILRYNVNFSKPSIVQNTWTEKLGWGNEERCQYHGSLKNHLVDELPLCNKQTGRIISEKSSNDDATMELSLSNANFPFLKGSPFTAALWFGLEGFHMTINGRHETSFAYREKLEPWLVSAVKVSGGLKILSVLATRLPIPDDHASLIIEEKLKAPSLSGTRIELLVGVFSTGNNFKRRMALRRSWMQYEAVRSGKVAVRFLIGLHTNEKVNLEMWRESKAYGDIQFMPFVDYYGLLSLKTVALCILGTKVIPAKYIMKTDDDAFVRIDELLSSLEERPSSALLYGLISFDSSPDREQGSKWFIPKEEWPLDSYPPWAHGPGYIISHDIAKFVVKGHRQRDLGLFKLEDVAMGIWIQQFNQTIKRVKYINDKRFHNSDCKSNYILVHYQTPRLILCLWEKLQKENQSICCE
Protein: DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) (A0A1B9ILM8)
Organism: Kwoniella mangroviensis CBS 10435
Interaction partners:
- YDG domain-containing protein
- Proliferating cell nuclear antigen
- SET domain-containing protein
- ubiquitinyl hydrolase 1
- Polyubiquitin
- dTDP-4-dehydrorhamnose reductase
- Histone H3
- Histone H3
- Histone H3
- Histone H3
Sequence:
MSSSDIIEIDDSDSELELIDMTSRSTSTSSSTRRSGDDDNKKRKRECVIEVISSDDDEDNEEIRTQLRELSVQEELVEAKEKQTETLRSSHRNTPSKRYRSHISINSSTCPPDHMQSHHPFRSQNATGYRPHLKSHLTWIVDTTDSPVERQSTYDVDGFEERCIKIYRKGFIHDDVEFIVDNAIVLPHRPPLYALIRSIFTLKFDDVSIKDKHFAHVHYIKSPNPHTDSSGRDGELFLRNAQCQDISIKQILKGQKLDFELIGGIKGKRRGSSKYFCQFVDQPSLSTIREPVFQDGFDRCDSCASRHQKHKFDDPRVLGDTLHFCDDGYHMHDFITVDPKIRGRPFLIGQIQGWSRVNGQLMVRMRRLKRFGEVIGAKYNGFVSNRRLVVTDKYEEHLVQSIMGKVYVLPKEEDAQYLDGHKAFWCSEGITNSHVSSTIAALQRPLRTCLSCLEVEKQKHQDVVNCIKACRFTAADYYSGAGGFILPGLDIFEWVSATDADKVACQTLHYLKREAPRMTVHYGRVREIYQYTTSRNSPTGPKAFPSPGTVFLMTGGPPCQGHSRVNHANNLSAGKNPDPRNDELWIMLAEVFRLRPYVVIIENVSAFKDDKGGDAGMQGEHNYGRAAMKELSQNGYSCRLGIVDSRGYGTPQNRLRTFIQGVRMGLSLPEFPTPSHANPKTTATVFKTDKAESLKPFYLGQRATPGTGLHPAVTIRDAVSDFPAFEYLPPPGIPRIPRRPQIPVFEGGRDGQQGNRTRVGFAHQIPYASTPSNDYQKEKRGEATSVHDHHTSYVTDGAKKIIFASAREAKPQGCDRRAIGSEGFSTLLTNSSPGQKGTAVIHFSQDRKFTIAERKRAMGWPDWHRLAGSPLDQDRQTGNGVCFESVQAIYLELVKEIILPWWIEAGRPTEDVFGKFKIDHP
Protein: KLF transcription factor 15 (Klf15 protein) (Kruppel-like factor 15) (Q5FVT6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVDHLLPVDETFSSPKCPVGYLGDRLASRQPYHMLPSPISEDDSDVSSPCSCASPDSQAFCSCYSAGPGPEAQGSILDFLLSRATLGSGGASGGVGDGSGPVTWGSWRRASVPVKEEHLCFPEFLSGDPDDVSRPFQPTLEEIEEFLEENMEAEVKEAPESSSRDLEACSQLSAGSHRSHLHPESGGRECRTPPPGGTSGGGTQGAGEGSAHDGPMPVLLQIQPVAVKQEAGAGPASPGQAPESVKVAQLLVNIQGQTFALLPQVVPSSNLNLSSKFVRIAPVPIAAKPIGSGSLGPGPAGLLVGQKFPKNPAAELLKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRAVRAIN
Protein: Fasciclin II transmembrane protein isoform (Q6RKB3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MSLLLSFYLLGLLVSSGQALLQVTISLSKVELSVGESKFFTCTAIGEPESIDWYNPQGEKIISTQRVMLQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVLSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTIPDNRFAVLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAIVMPQKSFNATAERGEEMTLTCKASGSPDPAISWFRNGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTSENGHVTLICEAEGEPVPEITWKRAIDGVTFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIEYAPKFVSNQTMYYSWEGNPINISCDVKANPPASIHWRREKLVLPAENTTHLKTHSVGRKMILEIARTSDNDFGRYNCTATNRLGTRFQEYILELADVPSSPRGVKIIELSQTTAKISFNKPESHGGVPIHHYQVDVMEETSETWKIVRSHGVQTTVVLSSLEPNTTYEVRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKISITKQDDGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFNGLGLGAIIGLGVAALLLILVVTDVSCFFIRQCGLLMCITRRMCGKKSGSSGKSKELEEGKAAYLKDGSKEPIVEMRTEDERITNHEDGSPVNEPNETTPLTEPEKLPLKEENGKEVLNAETIEIKVSNDIIQSKEDDIKA
Protein: Bcl-2-associated transcription factor 1 (Btf) (Q8K019)
Organism: Mus musculus (Mouse)
Function: Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Nucleus speckle {ECO:0000250|UniProtKB:Q9NYF8}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9NYF8}.
Interaction partners:
- Thyroid hormone receptor-associated protein 3
- Emerin
- Apoptosis regulator Bcl-2
- Histone H2AX
- Transcriptional regulator ATRX
- U2 snRNP-associated SURP motif-containing protein
- THO complex subunit 2
- Serine/arginine-rich splicing factor 10
- G2/mitotic-specific cyclin-B1
- Matrin-3
Sequence:
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRIYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTITPQNAPREESRGRSSFYPEGDQETAKTGKFLKRFTDEESRVFLLDRGNIRDKEAPKEKGSEKGRADGDWDDQEVLDYFSDKESAKQKFHDSEGDDTEETEDYRQFRKSVLADQGKSFATSSHRNTEEEGPKYKSKVSLKGNRESDGFREEKNYKLKETAYIVERPSTAKDKHKEEDKGSDRITVKKEVQSPEQVKSEKLKELFDYSPPLHKSLDAREKSIFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQANKSTSESFIQHIVSLVHHVKEQYFKSPAVTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSALRKHTRLAGEERGFKEEIQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKPYKDDSKHKGRERDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKDYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDDEETMENNEEKKDRRKEEKE