wanglab/gogpt-training-data huggingface dataset:
Protein: LATD/NIP (Peptide/nitrate transporter plant) (Putative proton-dependent oligopeptide transporter family, major facilitator superfamily) (D2IU94)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MEYTNSDDATNEKLIENGSSSSSSQPRKGGLRTMPFIIVNECLEKVASYGIMPNMILYLRDDYNMPIAKASYVLSTWSAMSNVLSIFGAFLSDSYLGRFNVITIGSFSSLLGLTVLWLTAMIPVLKPTCASLFEICNSATSSQQAVLFLSLGLISIGAGCVRPCSIAFGAEQLTIKGNSGDGNGRILDSYFNWYYTSISVSTIIALSVIAYIQENLGWKIGFGVPAVLMLVSVISFIIGSPLYVKVKPSESLLTNFARVVVVATKNRKLSLPDHDSDRYCQGHDSKLKVPTDSLRFLNKACVIRNPETDLNRDGSISNPWNLCTIEQVESLKSLLRVIPMWSTGIFMMATQSSFSTLQAKTLNRTLFGNFNFPAGSFNLILIFTLTIVIPLYDRVGVPLLAKYAGRPRGFSFKVRIGIGMLFAIVAKAVAAIVETVRRNAAIEQGFEDQPNAEINMSALWLAPEFILFGFAEAFTPVGLVEFFYCFFPKSMSSFAMAMFTLGLACSDVVSGVLVSIVDTVTSIGGNESWLSTNINRGHLNYYYGLLTFLGILNYFYYLVICWAYGPIQGEKHEDSARKKDDKFGYRELPTS
Protein: Protein serrate (Protein beaded) (P18168)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as a ligand for Notch (N) receptor. Essential for proper ectodermal development. Serrate represents an element in a network of interacting molecules operating at the cell surface during the differentiation of certain tissues.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Neurogenic locus Notch protein
- Suppressor of hairless protein
- Protein numb
- E3 ubiquitin-protein ligase mind-bomb
- Fringe glycosyltransferase
- Hairy/enhancer-of-split related with YRPW motif protein
- ADAM10 endopeptidase
- Protein neuralized
- Homeotic protein distal-less
- ADAM10 endopeptidase
Sequence:
MFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLPSTIRDCRSLKSACNLIALILILLVHKISAAGNFELEILEISNTNSHLLNGYCCGMPAELRATKTIGCSPCTTAFRLCLKEYQTTEQGASISTGCSFGNATTKILGGSSFVLSDPGVGAIVLPFTFRWTKSFTLILQALDMYNTSYPDAERLIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPCATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECATSPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCLEGHCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSATTTTTTTTTATTTRKMAKPSGLPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMPGAPDKALQPHCRCAPGWTGLFCAEAIDQCRGQPCHNGGTCESGAGWFRCVCAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCEILLSDPKSACQNASNTISPYTALNRSQNWLDIALTGRTEDDENCNACVCENGTSRCTNLWCGLPNCYKVDPLSKSSNLSGVCKQHEVCVPALSETCLSSPCNVRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVGKGASVEGLCSLVRVLLAAQLIKKPASTFGQDPGMLMVLCDLKTGTNDTVELTVSSSKLNDPQLPVAVGLLGELLSFRQLNGIQRRKELELQHAKLAALTSIVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFISLYWKQRLAYRTSSGMNLTPSLDALRHEEEKSNNLQNEENLRRYTNPLKGSTSSLRAATGMELSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQILLHKTQNSDMRKNTVGSLDSPRKDFGKRSINCKSMPPSSGDEGSDVLATTVMV
Protein: Flagellar filament 41 kDa core protein (Flagellin) (41 kDa antigen) (P41) (P11089)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Component of the core of the flagella.
Subcellular location: Periplasmic flagellum. Periplasm.
Interaction partners:
- Flagellar protein FliS
- Flagellar assembly factor FliW
- Flagellar hook protein FlgE
- Flagellar basal body rod protein FlgB
- Basal-body rod modification protein FlgD
- Flagellar motor switch protein FliM
- Purine-binding chemotaxis protein
- Motility protein A
- Flagellar motor switch protein FliN
- Flagellum-specific ATP synthase
Sequence:
MIINHNTSAINASRNNGINAANLSKTQEKLSSGYRINRASDDAAGMGVSGKINAQIRGLSQASRNTSKAINFIQTTEGNLNEVEKVLVRMKELAVQSGNGTYSDADRGSIQIEIEQLTDEINRIADQAQYNQMHMLSNKSASQNVRTAEELGMQPAKINTPASLSGSQASWTLRVHVGANQDEAIAVNIYAANVANLFSGEGAQTAQAAPVQEGVQQEGAQQPAPATAPSQGGVNSPVNVTTTVDANTSLAKIENAIRMISDQRANLGAFQNRLESIKDSTEYAIENLKASYAQIKDATMTDEVVAATTNSILTQSAMAMIAQANQVPQYVLSLLR
Protein: Dachshund variant 3 (Q24031)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHGMPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTASNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGPLGIDAHAAVPASSTETLLRNIQSLLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNIKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN
Protein: SOUL heme-binding family protein (F4K452)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Heme oxygenase 1, chloroplastic
- Heme binding protein
- Ferrochelatase-2, chloroplastic
- NTF2-like protein
- Translocator protein homolog
Sequence:
MATVNQQLYRPILTAVGSDCRRHVTTRFLPVPRRNVTTRLRPILSLEVGKEVASAPSTVNMEELVGFLYEDLPHLFDDQGIDKTAYDERVKFRDPITKHDTISGYLFNIAFLKNIFTPQFQLHWAKQTGPYEITTRWTMVMKFIPLPWKPELVFTGLSIMEVNPETNKFCSHLDLWDSIKNNDYFSLEGLVDVFKQLRIYKTPDLETPKYQILKRTANYEVRNYEPFIVVETIGDKLSGSSGFNNVAGYIFGKNSTMEKIPMTTPVFTQTTDTQLSSDVSVQIVIPSGKDLSSLPMPNEEKVNLKKLEGGFAAAVKFSGKPTEDVVQAKENELRSSLSKDGLRAKKGCMLARYNDPGRTWNFIMSQVLSFSSDSWLSSVLCDCLAFAEERSYHMA
Protein: Nucleoside diphosphate kinase, putative (EC 2.7.4.6) (Q38DQ0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- CTP synthase
- Ribonucleoside-diphosphate reductase
- Guanylate kinase, putative
- Guanylate kinase, putative
- dTMP kinase
- 40S ribosomal protein S13, putative
- dTMP kinase
- Pyruvate kinase
- Nucleoside diphosphate kinase
- Nucleoside diphosphate kinase, putative
Sequence:
MTALERYAFKVDYCDPQANLVRQYLLLYFAEDSTIEMHDLKTKRVFLKRCAYPSLTPRELFIGATVGVFSRSLKLVDYGDEVTRRHFSGSEAEFVVFIQEGGLCHMGSIIDRMHTWELRITNIRLVDLPDSLCRDLGVSRRCVAILFKGSNAIEKVGGLSTEFPNMTVVVAEPSDVNSVRGAAFGPGGTTAVMKNCSVCVIKPHAIMSGYQGAIIQRLIDEGFHITALGMYSLTVADAEDFLEVYNGVVPEYQRLVEQMSSGPCWAVQVCAENSVSALRAICGPHDPDVCHVLFPHTIRSKYGVDRTRNGVHCTDLEEDAPLESEFFFSLLQNA
Protein: Baseplate protein gp16 (Gene product 16) (Gp16) (Tail-associated lysine-like protein) (D3KFX4)
Organism: Lactococcus phage p2 (Lactococcus lactis bacteriophage p2)
Function: Forms a dome thereby closing the central channel at the end of the baseplate. Changes its conformation upon activation by calcium allowing the channel to open at the bottom of the baseplate for DNA ejection.
Subcellular location: Virion {ECO:0000269|PubMed:20351260, ECO:0000269|PubMed:24027307}. Note=Part of the baseplate. {ECO:0000269|PubMed:20351260}.
Interaction partners:
Sequence:
MLEANVYDNFNPNYYNISDFSMPNGKKEKRGLPIPKARCQVINYELWETGYLYTSSATLTVSVEVGDIVQILFPEVVPIEEALGKKKKLNLDMVYLVTDVDESNKATLKNYFWAMIESLDVPNAITKTTNFAIIDYLIDPNKNNLMSYGYFFNSSIFAGKATINRKAETSSAHDVAKRIFSKVQFQPTTTIQHAPSETDPRNLLFINFASRNWNRKRITTRVDIKQSVTMDTETIVERSAYNFAVVFVKNKATDDYTDPPKMYIAKNNGDVIDYSTYHGDGTDLPDVRTAKTLFYDRDDHGNPPELSTIKVEISPSTIVTRLIFNQNELLPLYVNDLVDIWYEGKLYSGYIADRVKTEFNDRLIFVESGDKPNVI
Protein: Interleukin 20 receptor beta (E9Q9A6)
Organism: Mus musculus (Mouse)
Interaction partners:
- Interleukin-20 receptor subunit alpha
- Interleukin-24
- Interleukin-22 receptor subunit alpha-1
- Interleukin-19
- Interleukin-20
- Interleukin-10
- Interleukin-22
- Interleukin-6
- Interleukin-10 receptor subunit alpha
- Interferon lambda-3
Sequence:
MISQGVWTSPFMWFFYSMTSGFLTDAVSVLPAPQNLSVQSTNMKHLLMWNPVTQPGETVLYCVEYQGEYESLYMSHIWIPSSQCSPTKSLECDVTDDITATVPYNFRVKAMLGSQTSAWSNLEHPFNRNATVLTPPRMEVTEHGLHLVIELEDLGPQFEFLVVYWRREPGAAEHVKMVRSGDIPVHLETMEPGAMYCVKAQALVKAIGRHSAFSQPTCVEMQGESLPLALALFAFVGFMLILVVVLLSVWKMGQLLRYSCCPAVVLPDTLKITSSSQKLISCRKEEVDACAVAVLSSEHLFGVWISQT
Protein: GTP-binding protein rhoC (Rho3 protein homolog) (Q96WY0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Rho GTPase activator Rga
- Uncharacterized protein
- SH3 domain protein
- Rho GDP-dissociation inhibitor
- Uncharacterized protein
- protein kinase C
- Actin, gamma
- Twinfilin
- Rho guanyl nucleotide exchange factor, putative
- Rho GTPase activator
Sequence:
MSGSMYDDQYYATSRRHSLVTPPPSVAPRQNRMRSQSVRVSNGTVSTDNSMSSGRVSEATNITQPPAYSKKFVVVGDGGCGKTCLLISYSQGYFPEKYVPTVFENYITQTLHRRSGKTVELALWDTAGQEEYDRLRPLSYPETDLLFVCFAIDCPASLENVMDKWYPEVLHFCPTTPIILVGLKSDLRNKRTCIELLKTQGLTPVTPEQGQAVAGRMNASYVECSSKEMRGVDSVFQLAVDTVVSLEEQNWDTRLPSSSGKPGGKPIGGKKIKKRSCKIL
Protein: Mediator of RNA polymerase II transcription subunit 15a (F4I171)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 8
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 32
- Mediator of RNA polymerase II transcription subunit 25
- Mediator of RNA polymerase II transcription subunit 27
- Mediator of RNA polymerase II transcription subunit 19a
- Mediator of RNA polymerase II transcription subunit 23
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 20a
Sequence:
MDNNNWRPSLPNGEPAMDTGDWRTQLPPDSRQKIVNKIMETLKKHLPFSGPEGINELRRIAARFEEKIFSGALNQTDYLRKISMKMLTMETKSQNAAGSSAAIPAANNGTSIDSIPTNQGQLLPGSLSTNQSQAPQPLLSQTMQNNTASGMTGSTALPSSMPPVSSITNNNTTSVVNQNANMQNVAGMLQDSSGQHGLSSNMFSGPQRQMLGRPHAMSSQQQQQPYLYQQQLQQQLLKQNFQSGNVPNPNSLLPSHIQQQQQNVLQPNQLHSSQQPGVPTSATQPSTVNSAPLQGLHTNQQSSPQLSSQQTTQSMLRQHQSSMLRQHPQSQQASGIHQQQSSLPQQSISPLQQQPTQLMRQQAANSSGIQQKQMMGQHVVGDMQQQHQQRLLNQQNNVMNIQQQQSQQQPLQQPQQQQKQQPPAQQQLMSQQNSLQATHQNPLGTQSNVAGLQQPQQQMLNSQVGNSSLQNNQHSVHMLSQPTVGLQRTHQAGHGLYSSQGQQSQNQPSQQQMMPQLQSHHQQLGLQQQPNLLQQDVQQRLQASGQVTGSLLPPQNVVDQQRQLYQSQRTLPEMPSSSLDSTAQTESANGGDWQEEVYQKIKSMKETYLPDLNEIYQRVAAKLQQDSMPQQQRSDQLEKLRQFKTMLERMIQFLSVSKSNIMPALKDKVAYYEKQIIGFLNMHRPRKPVQQGQLPQSQMQPMQQPQSQTVQDQSHDNQTNPQMQSMSMQGAGPRAQQSSMTNMQSNVLSSRPGVSAPQQNIPSSIPASSLESGQGNTLNNGQQVAMGSMQQNTSQLVNNSSASAQSGLSTLQSNVNQPQLSSSLLQHQHLKQQQDQQMQLKQQFQQRQMQQQQLQARQQQQQQQLQARQQAAQLQQMNDMNDLTSRQGMNVSRGMFQQHSMQGQRANYPLQQLKPGAVSSPQLLQGASPQMSQHLSPQVDQKNTVNKMGTPLQPANSPFVVPSPSSTPLAPSPMQVDSEKPGSSSLSMGNIARQQATGMQGVVQSLAIGTPGISASPLLQEFTSPDGNILNSSTITSGKPSATELPIERLIRAVKSISPQALSSAVSDIGSVVSMVDRIAGSAPGNGSRASVGEDLVAMTKCRLQARNFMTQEGMMATKKMKRHTTAMPLSVASLGGSVGDNYKQFAGSETSDLESTATSDGKKARTETEHALLEEIKEINQRLIDTVVEISDDEDAADPSEVAISSIGCEGTTVRFSFIAVSLSPALKAHLSSTQMSPIQPLRLLVPCSYPNGSPSLLDKLPVETSKENEDLSSKAMARFNILLRSLSQPMSLKDIAKTWDACARAVICEYAQQFGGGTFSSKYGTWEKYVAAS
Protein: GDT1 family protein (A0A1D8PH63)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}.
Interaction partners:
- Calcium-transporting ATPase
- Solute carrier RCH1
- Vacuolar calcium ion transporter
Sequence:
MKVSKFLFTLTLLSSSCLAIIENIDGSIEDTDSLLTKTVDKSSHKLGVQPLEDEDNHPTPKHAKQPLDPYKNGGKLGHESSSSSSLSSSSSNQDQELPDTSYNAFIMSISMIIVSEIGDKTFLIAALMAMRNSRIVVFSAAFSSLVVMTVLSGIVGHALPTLISQRLTQFLASALFIIFGVKLLREGLAMSKDVGVDEEMAEVEEEIAMSKLNTQMNDIEGGGVSNTEGVTNSSISNNNTPVYAEIGNQIQNLATFVFTPVWIQVFVMTFLGEWGDRSQIATIAMAAGSEYWFVIFGAIIGHGLCTAAACIGGKYLAKKISMRNVTIGGAIAFFIFSILYFYDAYYGIES
Protein: Aspartic protease 4 (EC 3.4.23.-) (Q21966)
Organism: Caenorhabditis elegans
Function: Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12410314}. Lysosome {ECO:0000269|PubMed:12410314}. Secreted {ECO:0000305}.
Interaction partners:
- Gut-specific cysteine proteinase
- Cathepsin B-like cysteine proteinase 6
- Peptidase C1A papain C-terminal domain-containing protein
- Peptidase C1A papain C-terminal domain-containing protein
- Peptidase C1A papain C-terminal domain-containing protein
- Cathepsin B-like cysteine proteinase 4
- Peptidase C1A papain C-terminal domain-containing protein
- Peptidase C1A papain C-terminal domain-containing protein
- Cathepsin B-like cysteine proteinase 5
- Cathepsin B-like cysteine proteinase 3
Sequence:
MNRCILLLLGALLLVQGLHVHKRQQKLRTVSLKKQPTLRETLLQAGSFETFAKHRHGYKKYLKTNGNHHFDKYQALNVEGEIDELLRNYMDAQYFGTISIGTPAQNFTVIFDTGSSNLWIPSKKCPFYDIACMLHHRYDSKSSSTYKEDGRKMAIQYGTGSMKGFISKDSVCVAGVCAEDQPFAEATSEPGITFVAAKFDGILGMAYPEIAVLGVQPVFNTLFEQKKVPSNLFSFWLNRNPDSEIGGEITFGGIDSRRYVEPITYVPVTRKGYWQFKMDKVVGSGVLGCSNGCQAIADTGTSLIAGPKAQIEAIQNFIGAEPLIKGEYMISCDKVPTLPPVSFVIGGQEFSLKGEDYVLKVSQGGKTICLSGFMGIDLPERVGELWILGDVFIGRYYSVFDFDQNRVGFAQAKTADGRPVDPAPRPFRSVFDNESEESMEQDDE
Protein: Myosin-binding protein 7 (Q9FG14)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Membrane-anchored myosin receptors that define a distinct, plant-specific transport vesicle compartment.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:23995081}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Myosin-17
- Myosin heavy chain-like protein
- Eukaryotic aspartyl protease family protein
- Transport/golgi organization-like protein
- At5g40190
- Membrane-anchored ubiquitin-fold protein 3
- Ubiquitin system component Cue protein
- Myosin-like protein
- Probable protein S-acyltransferase 13
- Myosin-9
Sequence:
MDLAIVSSPTRDVVRCCDCGCDCSLNGASPGSLLRSVKRKYEEFENEKLFHIPELELDLSSNAKVQIENELELLRETVSSQQQSIQDLYEELDEERNAASTAASEAMSMILRLQRDKAELQMELRQFKRFAEEKMEHDQQELLDLEDLIYKREQTIQALTFEAQAYKHRMMSFGFTEAEVETEKNMLSRNPSMIENDYQYDLPTSDYPPIKCNVNENPGPLEADIDVDDVEKYPLADSPHPLKTLERRISQMERNPSFTQPTGDVSGGRHYTEKNVVGQSPRHQRHFRRVSTGSASSLLGTTREKRLDFSNDSPRSNNGSFRKMEDPPYAAGNSFARDKGDSSEIGDNDMNDRVYTIDSVHHSVSHSGTAEQKFKNDTADGYAMSPREISNQPDLGDPEISKLYMRLQALEADRESMRQAIMSMRTEKAQMVLLKEIAQHLSKDVVPERRLPLRKTSIIGAFNFISVFKWITSFVFWRRKARRSKYMNGVQGNNMGLQMLLEKTPRIRQWRCLSSTQV
Protein: Shaggy-related protein kinase GSK2 (EC 2.7.11.1) (Glycogen synthase kinase3-like protein 2) (OsGSK2) (Shaggy/GSK3-like kinase 22) (OsSK22) (Q60EZ2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Serine-threonine kinase that acts as a negative regulator of brassinosteroid (BR) signaling. Phosphorylates DLT and BZR1, two positive regulators that mediates several BR responses. Phosphorylation of DLT and BZR1 inhibits their activities in BR signaling. Phosphorylates OFP8, a positive regulator of BR responses. Phosphorylated OFP8 shuttles from the nucleus to the cytoplasm where it is degraded by the proteasome. Phosphorylates the E3 ubiquitin-protein ligase PUB24, a negative regulator of BR signaling, which targets BZR1 and promotes its degradation via the 26S proteasome. Phosphorylation of PUB24 increases its stability. Phosphorylates the AP2-ERF transcription factor SMOS1, a positive regulator of BR signaling, which cooperatively functions in a transactivating complex with BZR1 to enhance the transcription of BR biosynthetic genes. Phosphorylation of SMOS1 leads to its degradation by an unknown mechanism.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22685166}. Nucleus {ECO:0000269|PubMed:22685166}.
Interaction partners:
- protein-serine/threonine phosphatase
- Os01g0185400 protein
- Protein BZR1 homolog 1
- Growth-regulating factor 4
- Shaggy-related protein kinase GSK1
- non-specific serine/threonine protein kinase
- Uridine kinase
- Os02g0708200 protein
- Phosphoribulokinase
- Os03g0382350 protein
Sequence:
MDQPAPAPEPMLLDAQPPAAVACDKKQQEGEAPYAEGNDAVTGHIISTTIGGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRAMDHPNVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANHRMPLIYVKLYMYQLFRGLAYIHTVPGVCHRDVKPQNVLVDPLTHQVKLCDFGSAKTLVPGEPNISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGESAVDQLVEIIKVLGTPTREEIRCMNPNYTEFRFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALDACAHPFFDELREPNARLPNGRPFPPLFNFKHELANSSQELISRLIPEHVRRQATHNFFNTGS
Protein: Fatty acid synthase (EC 1.1.1.100) (EC 1.3.1.39) (EC 2.3.1.41) (EC 2.3.1.85) (EC 3.1.2.14) (Q9VQL6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPSRKKAQGESAAGEDADIVISGLSGKLPESSNIEEFKYNLLNGIDMVTDEPRRWEAGIYGLPERMAKMKDSDLEKFDDKFFSVHQKQAELMDPCMRMLLELTHEAIIDAGINPVQLRGSRTGVYIGLSFVETEHEIPNMEPSSINGYCLTGCARAMFANRISYTFDFKGPSFIVDTACSSSLVALNHAFADMRAGRCDYALVAGVNLILKPIFALQFLRLGIVSHDGSCKTFDAAANGYARADTCAVVLLQRRKEAKRVYASILNVRTNTDGFKEQGVTFPDGRMQQALLEETYSEIGLNPDEVVYVEAHGSGTPVGDDQEANMLSNFFCRPSRSTPLLIGSVKSNMGHAEPASGVSALAKMIIAMEEGIIPKNLHYRTPNPSVPALVEGKLKVVDRNLPWQGGIVGLNSFGFGGANAHVVLKSHTKAKEPKACPKAGEAEQSLSLVTCSGRTEDAVNQLLKVATEQRHDQELLTLINDIHSHPIPLHPFRGYAVLGTSGCVKEEVLPYEEEERPIWFVYAGMGSQWARMAKDLMQLEVFRNSIQHCAEVLAQVDFDLIDVLTRSTERTFDNMLYSFVSVSAVQVALTDLLRVLDIRPDGIIGHSAGELGAAYMDGCLTAEQTVLAAYWRGRSVLDTPDLPRGKMAAVGLSWEQIGSQIPKDCYPVCHNSDDNCTVSGPPSSMDAMIEDLTAKGIFVREVGSGGYAFHSPYIEGAAPMLRRSLERLITEPKKKSIRWLSTSVKEAEWDSEKNHLASAGYFINNLISPVLFHQAVKRIPQNALIVEIAPHGLFRAILRSLSPQISYVSLMQRGHANNFEFLLSQLGRLYAAGGQPQILKISPSIPYPVSRGTPMLGSLVGWDHTQKWNYPKFKGGRQAGQLSVELDLGKEENVYLAGHTIDGRVLFPATGYMTLAWMSLAQQQGLDYLRTPVLFEDVVFHRATILSVGTVVKLTLNFFPGSSSFEICEGTSLVTSGKIRLVSNVQQEQLQLSSLPGIAGSNKLSTKDIYKELRLRGYDYTGVFQGILESDISAVTGQLQWADNWISFMDTMLQFRILSNDIRELYVPTGIERALIDPLKHLELAKKHQQKLTVNWHRNISVVKCGGVEIHKMKTAQTQRRSGGQSPPSLERYRFWPHSQHLGQREEQEKSRSTALAVAIQLIIENSGGAVKLKGVELAGSRSTLDALSAVQLLELIEREPILVGDMAVVTSSSNESELGEQLKEHGIRVIVKDIKAGAVEQQCHFVYSVNMLAQNSVKDLQHCLDSLKSDSGFLLLEEAASRYNIIGKEKLNKLKLVSVLEQFFGTDRVLVLVRKLSKVQSSQALTLHLTNKQFKWVNELKNSIAKAQAEEKNLYLVAQGEPNSGALGLMNCLKREAGGHFLRLYLILDEGVPQFSLDDPFYAAQLAKDLVVNVYRNGSWGSYRHLKMESRPPMLPVEQAYVNTLVKGDLSSLRWIESPRSSPIQSQLEPCTVYYAPLNFRDVMLASGKLGVDALPGDLAYQDCVLGLEFAGRDSCGRRVMAMVTAKSLATNCLANRNLLWEVPSKWTMEQASTVPCVYATVYYALVVRGQMKEGERILIHAGSGGVGQAAISVALAHGLTVFTTVGSKEKREFLLKRFPKLKAKNIGNSRDTSFEQLIMSETHGNGVELVLNSLSEEKLQASIRCLALNGRFLEIGKFDLSNNTPLGMSVFLKNTSFHGILLDSVMEGEEEMQLMVAKLVAEGIKSGAVQPLPTTVFAEQEIEKAFRFMASGKHIGKVVIKVRLEEEQQAALPRLRQIQAIPRSYMHPEKSYILVGGLGGFGLELANWLVSRGARFLVLSSRSGVKSGYQALMIRRWHDRGVQVQIDTNDVTTAVGCQRLLEVSNKLALVGGIFNLAAVLRDGLIEDQSPKNFEKVSAPKLLATIHLDKISREICPALEYFVCFSSLSCGRGNMGQTNYGLANSTMERICEQRQEYGYPGTAIQWGAIGDTGLIIEHMGNNETVVGGTLPQRMISCLETLDLFLQQPHPVMASMVVAEKRKTEQANRLSLIATIANIMGLRDVKSVSDKTTLFDLGMDSLMSTEIKQTLERHFDLVLSAQEIRQLTFSALRQIDAQEPPSASVSSPSASSTLSRIKEEACVEVQPQSDETRKVFAKEVLPQEVMVRLRSKAPVASEDPAVFFLAPIEGFTIAVEALAASLTCPAYGLQCTEQVPLDSIEACAAYYLRQIQKLQPLGPYHIVGYSYGCLLAHAIAVALEQRRFGVKVIMLDGAPTMASGYVQEAKKQTDDLNRQQSMTLAYFGALLADVDYNQLLQLLDGVQTWPSKLDKLADTLAGYTQQTREVIKKAACMFKQKLLLSESYKGAKQLHSDVVLIKSAEHNAIMAQDYGLKEICSAQIDMHVVEGTHRTFLKEPHTLQIIERVLRKRP
Protein: Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1) (P56391)
Organism: Mus musculus (Mouse)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:34616041, ECO:0000269|PubMed:38575788}; Peripheral membrane protein {ECO:0000269|PubMed:34616041, ECO:0000269|PubMed:38575788}; Intermembrane side {ECO:0000269|PubMed:34616041, ECO:0000269|PubMed:38575788}.
Interaction partners:
- Cytochrome c oxidase subunit 6C
- Cytochrome b-c1 complex subunit 9
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 5B, mitochondrial
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
- Cytochrome b-c1 complex subunit 10
- Cytochrome c oxidase subunit 7B, mitochondrial
- Cytochrome c oxidase subunit 3
Sequence:
MAEDIKTKIKNYKTAPFDSRFPNQNQTKNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPVSWVSAWDDRIAEGTFPGKI
Protein: Sec1/munc18-like (SM) proteins superfamily (F4JPL6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEESINQNPEAMEALISNLFGNISSLKSAYIELQSAHTPYDPEKIQAADKVVISELKNLSEMKHFYRENNPKPVCVSPQDSRLAAEIQEQQSLLKTYEVMVKRSLMEQSLDAYDEKEKEMMMMIGSINRTELLSVLKAKGTNIDKLRFAIMYLISLESVNQTEVEAVEAALREAKIDTSTFQYVKKIKSLNVSLAANSASKSHIALWPVYKRGDRAGVKNLLSSDEKLAVARAVEC
Protein: FAD/NAD(P)-binding domain-containing protein (Q57UR1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLWKLFTSSMLAGAVSAYRSTSSSSLAISPPTLDVVMDPSKDVTPVRCVVVGGGYTGSKLAYMLDSMFNVTFIDEKNYFELTNDIIPIIANPWSELNEEACRRLLVLHRYYLKQANVLTGTVHGVDENTVTLRDGRTVPYDLLFITVGERKPYPFATKQRTVSGRVQELKNFNEFIGTCKKVAVLGGGPVGVSLAVDLARNRKDLKVHLYHSKPELLPALPTTSQRYALETVEKCDNITVNLCSRVTDVTGYDALGRRVNETSTSMLSSLLKPLTGWLTWGTSPDEPSTFTVRYEKMHFAPRPRQSIVNQAYFGTRQPQLTSNTVESTGEEEGYDYVFSTIGDVPRPIVSGKGCTNILSEHEMPDGHYRVSTLMQLYCRPNIWAVGRCNNIPRVRGYGLSDVEARTVFRALNSVVHNPTERFMHSRDGLDLRRLNIPRMLVRLGSDDAVGSTPWSGAMVGLAAVHEFMQDRNFLVKEFQKPIFYKRQDAAKVKQRISNWAAHEITDIVDFSHC
Protein: BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2) (Q8N8U9)
Organism: Homo sapiens (Human)
Function: Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.
Subcellular location: Secreted {ECO:0000269|PubMed:14766204}.
Interaction partners:
- Bone morphogenetic protein 4
- Bone morphogenetic protein 6
- Bone morphogenetic protein 2
- Bone morphogenetic protein 7
- Ubiquitin-like protein FUBI
- Chordin
- Twisted gastrulation protein homolog 1
- Inhibin beta A chain
Sequence:
MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCPQR