wanglab/gogpt-training-data huggingface dataset:
Protein: Cobalt/magnesium transport protein CorA (Q9WZ31)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Function: Mediates influx of magnesium ions. Mediates Co(2+) uptake. Has high selectivity for Co(2+). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:23112165, ECO:0000305|PubMed:16598263, ECO:0000305|PubMed:16857941, ECO:0000305|PubMed:16902408, ECO:0000305|PubMed:18276588, ECO:0000305|PubMed:21454699, ECO:0000305|PubMed:22722933, ECO:0000305|PubMed:23091000, ECO:0000305|PubMed:23425532, ECO:0000305|PubMed:23781956, ECO:0000305|PubMed:26871634}; Multi-pass membrane protein {ECO:0000269|PubMed:16598263, ECO:0000269|PubMed:16857941, ECO:0000269|PubMed:16902408, ECO:0000269|PubMed:23112165, ECO:0000269|PubMed:23425532, ECO:0000269|PubMed:26871634, ECO:0000305|PubMed:23091000}.
Interaction partners:
Sequence:
MEEKRLSAKKGLPPGTLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLEDILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRDVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGMNFEYMPELRWKWGYPVVLAVMGVIAVIMVVYFKKKKWL
Protein: Rho GTPase activating protein 5 (A0A0G2K7N9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Proto-oncogene tyrosine-protein kinase Src
- Transforming protein RhoA
- RSA-14-44 protein.
- Rho GTPase-activating protein 35
- Thy-1 membrane glycoprotein
- Rho-related GTP-binding protein RhoE
- Ras GTPase-activating protein 1
Sequence:
MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLNWLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLANSLLHSDHNRSRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDIILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDSSDNYAEPLDTIFKQKGYPDEIYVVPDDSQNRIIKIRNSFVNNTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFPTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQEVDDKKIKKKPHKVKEDKKKKKTKTFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAAPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII
Protein: ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1) (Q09429)
Organism: Rattus norvegicus (Rat)
Function: Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q09428}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q09428}.
Interaction partners:
- ATP-sensitive inward rectifier potassium channel 11
- ATP-sensitive inward rectifier potassium channel 8
- Rap guanine nucleotide exchange factor 4
- Transient receptor potential cation channel subfamily M member 4
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- ATP-binding cassette sub-family C member 9
- Rap guanine nucleotide exchange factor 3
- Hexokinase-4
- Syntaxin-1A
Sequence:
MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYVFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCLAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEKTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSTDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK
Protein: Peptide chain release factor RF2 (RF-2) (P07012)
Organism: Escherichia coli (strain K12)
Function: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. Acts as a peptidyl-tRNA hydrolase. In the presence of truncated mRNA in the 70S ribosome, ArfA and RF2 interact such that the GGQ peptide hydrolysis motif of RF2 rises into the peptidyl-transferase center and releases the ribosome. Recruited by ArfA to rescue stalled ribosomes in the absence of a normal stop codon.
Subcellular location: Cytoplasm. Note=Recruited to the 70S ribosome by ArfA even in the absence of mRNA (PubMed:22922063, PubMed:25355516, PubMed:27934701). {ECO:0000269|PubMed:22922063, ECO:0000269|PubMed:25355516, ECO:0000269|PubMed:27934701}.
Interaction partners:
- Alternative ribosome-rescue factor A
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein bL27
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein bS6
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein bL21
- Small ribosomal subunit protein bS18
- Large ribosomal subunit protein uL16
- Small ribosomal subunit protein uS12
Sequence:
MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
Protein: DNA-3-methyladenine glycosylase I (Q9AB52)
Organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus)
Interaction partners:
- GMP synthase
Sequence:
MNYIARCTWKGMNGDPFYEAYHDTEWGVPEWDSRALWEKLVLDGFQAGLSWITILRKREAFRAAFANFDPEKVARFDETDRARLMADAGIIRSNGKIDATIAGARLYLDMRERGEDFGQFLWDMVGGAPIQNQWEAGQVPAQTPLAVEMSKALKAKGFKFCGPVIVYAFMQATGLVNDHLVSCFRHEDCKALGRH
Protein: NAD(P)H-quinone oxidoreductase subunit K, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit K) (NADH-plastoquinone oxidoreductase subunit K) (Q6ENH0)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01356}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01356}; Stromal side {ECO:0000255|HAMAP-Rule:MF_01356}.
Interaction partners:
- NAD
- NAD
- NAD
- NAD
- NAD
- Uncharacterized protein
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Uncharacterized protein
- NAD
- NAD
Sequence:
MSLIEFPLLDQTSSNSVISTTLKDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDALTKLRKKISREIVEDRTLSQKKNRCFTTSHKLYVRRSTNTGTYEQELLYQSPSTLDISSETFFKSKSPVSSYKLVN
Protein: EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1) (O95967)
Organism: Homo sapiens (Human)
Function: Plays a crucial role in elastic fiber formation in tissue, and in the formation of ultrastructural connections between elastic laminae and smooth muscle cells in the aorta, therefore participates in terminal differentiation and maturation of smooth muscle cell (SMC) and in the mechanical properties and wall integrity maintenance of the aorta. In addition, is involved in the control of collagen fibril assembly in tissue throught proteolytic activation of LOX leading to cross- linking of collagen and elastin (By similarity). Also promotes ELN coacervation and participates in the deposition of ELN coacervates on to microfibrils but also regulates ELN cross- linking through LOX interaction. Moreover adheres to the cells through heparin binding in a calcium-dependent manner and regulates vascularlar smooth muscle cells proliferation through angiotensin signaling.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:20389311, ECO:0000269|PubMed:27339457}. Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250|UniProtKB:Q9WVJ9}. Note=Localizes on the microfibrils surrounding ELN cores. {ECO:0000250|UniProtKB:Q9WVJ9}.
Interaction partners:
- Elastin
- Protein-lysine 6-oxidase
- V-type proton ATPase 116 kDa subunit a 2
- Fibrillin-1
- A disintegrin and metalloproteinase with thrombospondin motifs 2
- Fibulin-5
- Microfibrillar-associated protein 2
- Pyrroline-5-carboxylate reductase 1, mitochondrial
- Microfibrillar-associated protein 5
- Alpha-1,3/1,6-mannosyltransferase ALG2
Sequence:
MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
Protein: Neuropilin-1 (A5 protein) (P79795)
Organism: Gallus gallus (Chicken)
Function: Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By similarity). Mediates the chemorepulsant activity of semaphorins. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). Regulates mitochondrial iron transport via interaction (By similarity).
Subcellular location: Mitochondrion membrane {ECO:0000250|UniProtKB:O14786}; Single-pass type I membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O14786}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Semaphorin-3A
- Vascular endothelial growth factor receptor 2
- Plexin A2.
- Plexin A1.
- Plexin-A4
- Vascular endothelial growth factor receptor 1
- Semaphorin-3C
- Plexin-D1
- Sema domain-containing protein
- Placental growth factor
Sequence:
MDWGLFLHCAALTFTLSRALRSDKCGDTIKILSPGYLTSPGYPQSYHPSQKCEWLIQAPEPYQRIMINFNPHFDLEDRDCKYDYVEVIDGDNAEGRLWGKYCGKIAPPPLVSSGPYLFIKFVSDYETHGAGFSIRYEVFKRGPECSRNFTSSSGMIKSPGFPEKYPNSLECTYIIFAPKMSEIILEFESFELEPDSNTPGGAFCRYDRLEIWDGFPDVGPHIGRYCGQNNPGRVRSSTGILSMVFYTDSAIAKEGFSANYSVSQSSVSEDFQCMEPLGMESGEIHSDQITVSSQYSAIWSSERSRLNYPENGWTPGEDSVREWIQVDLGLLRFVSGIGTQGAISKETKKEYYLKTYRVDVSSNGEDWITLKEGNKPVVFQGNSNPTDVVYRPFPKPVLTRFVRIKPVSWENGVSLRFEVYGCKITDYPCSGMLGMVSGLIPDSQITASTQVDRNWIPENARLITSRSGWALPPTTHPYTNEWLQIDLGEEKIVRGIIVQGGKHRENKVFMKKFKIGYSNNGSDWKMIMDSSKKKIKTFEGNTNYDTPELRTFEPVSTRIIRVYPERATHAGLGLRMELLGCELEAPTAVPTVSEGKPVDECDDDQANCHSGTGGTTVLNTEKPTVIDNTVQPELPPYNLNCGFGWGSHKTLCQWEHDNQVDLKWAILTSKTGPIQDHTGDGNFIYSQADESQKGKVARLLSPIIYSQNSAHCMTFWYHMSGPHVGTLKIKLRYQKPDEYDQVLLSLNGHQANCWQEGRVLLHKSVKLYQVVIEGEIGKGNGGIAVDDINIDNHISQEDCQKSTDVESEIVEEDPESNQTGFTPSYRTDEDYDDISRKPGNVLKTLDPILITIIAMSALGVLLGAICGVVLYCACWHNGMSERNLSALENYNFELVDGVKLKKDKLNTQNSYSEA
Protein: BTB/POZ domain-containing protein 9 (Q6GML3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSDSHPLRPMNSASEIDHLHLLSEQLGALVPGEEYSDVTFVVEEKRFPAHRVILAARCQYFRALLYGGLRESRAQAEVRLEETRAEAFSMLLRYLYTGRATLSEAREETLLDFLGLAHRYGLQPLEVSICEFLRTLLSTRNVCLVFDVASLYCLNGLAEACMAYMDRNAVEVLKSDGFLTLSKSALLTVVRRDSFASSEREIFQALCHWCHHNGDGPEAKEVMSAVRLPLMTLSEMLNVVRPSGLLSPDDLLDAIQTRSESRDMDLNYRGMLIPEENIATMKHGAVVVKGELKSALLDGDTQNYDLDHGFSRHPIEEEGRAAGIQVRLGQPSIVNHIRLLLWDKDSRSYSYYVEVSMDELDWVRVVDHSKFLCRSWQQLYFPARVCRFIRVVGTHNTVNKVFHLVALECMYTLRPFTLEKGLLVPTENVATVQACASVVEGVSRSRNALLNGDTSHYDWDSGYTCHQLGSGAIVIQLAQPYMLGSMRLLLWDCDERSYSYYVELSTNQQNWVKIVDRTKDECRSWQTLTFDRQPASFIRIVGTHNTANEVFHCVHFECPAQMDTVVKEGSPGPDQPKPETSSQNSYSQSLMAQKPSSSSSHT
Protein: Uncharacterized protein CXorf66 (Q5JRM2)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Ubiquitin-like protein FUBI
- Small ribosomal subunit protein eS1
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL10
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein eL30
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein uS13
Sequence:
MNLVICVLLLSIWKNNCMTTNQTNGSSTTGDKPVESMQTKLNYLRRNLLILVGIIIMVFVFICFCYLHYNCLSDDASKAGMVKKKGIAAKSSKTSFSEAKTASQCSPETQPMLSTADKSSDSSSPERASAQSSTEKLIRPSSLQKPSIPNSAGKLTRPSYPKRSSKSSCSKKLSKSSHLEKAHKKGSLEKLCKLDYACKLASSDKPVRPPQLFKPLYSSHPQNEISPSKPFGPQELAKPPKHFNPKRSVSLGRAALLSNSELAETCQPYKKKHLVAKTYRPLVNDISEAKEKNTQNLHVSSKVKSSSRSFRKLDSRNNAYGDHVNDSDTMKYYSEVDSDKVIIITCDRGYNQVTSEVTLND
Protein: Probable Golgi SNAP receptor complex member 2 (Q9VRL2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:O35165}; Single-pass type IV membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:O35165}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O35165}. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. {ECO:0000250|UniProtKB:O35165}.
Interaction partners:
- BET1 homolog
- Golgi SNAP receptor complex member 1
- Syntaxin-5
- Secretory 22, isoform B
- LD34211p
- Protein sly1 homolog
- General vesicular transport factor p115
- LD27967p
- LD39211p
- Vesicle transport protein USE1
Sequence:
MESLYHQTNNVVKDIERDFQRLSQLSAQESLDVENGIQLKITQANANCDRLDVLLYKVPPSQRQSSKLRVDQLKYDLRHLQTSLQTARERRQRRMQEISEREQLLNHRFTANSAQPEETRLQLDYELQHHTQLGNAHRGVDDMIASGSGILESLISQRMTLGGAHKRIQAIGSTLGLSNHTMKLIERRLVEDRRIFIGGVVVTLLIIALIIYFLVL
Protein: Chaperone protein ClpB1 (ATP-dependent Clp protease ATP-binding subunit ClpB homolog 1) (Casein lytic proteinase B1) (Heat shock protein 101) (Protein DEFECTIVE IN LONG-TERM ACQUIRED THERMOTOLERANCE) (P42730)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Molecular chaperone that plays an important role in thermotolerance. Together with HSA32, required for long-term acquired thermotolerance (LAT) in plants and naturally high basal thermotolerance observed in germinating seedlings.
Subcellular location: Cytoplasm, cytosol. Nucleus {ECO:0000305}.
Interaction partners:
- Heat shock 70 kDa protein 4
- 17.6 kDa class II heat shock protein
- Heat stress transcription factor A-2
- Heat shock protein 21, chloroplastic
- Heat shock protein 90-1
- Heat shock 70 kDa protein 5
- 17.7 kDa class II heat shock protein
- 18.1 kDa class I heat shock protein
- Heat shock 70 kDa protein 8
- 26.5 kDa heat shock protein, mitochondrial
Sequence:
MNPEKFTHKTNETIATAHELAVNAGHAQFTPLHLAGALISDPTGIFPQAISSAGGENAAQSAERVINQALKKLPSQSPPPDDIPASSSLIKVIRRAQAAQKSRGDTHLAVDQLIMGLLEDSQIRDLLNEVGVATARVKSEVEKLRGKEGKKVESASGDTNFQALKTYGRDLVEQAGKLDPVIGRDEEIRRVVRILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPNSLTDVRLISLDMGALVAGAKYRGEFEERLKSVLKEVEDAEGKVILFIDEIHLVLGAGKTEGSMDAANLFKPMLARGQLRCIGATTLEEYRKYVEKDAAFERRFQQVYVAEPSVPDTISILRGLKEKYEGHHGVRIQDRALINAAQLSARYITGRHLPDKAIDLVDEACANVRVQLDSQPEEIDNLERKRMQLEIELHALEREKDKASKARLIEVRKELDDLRDKLQPLTMKYRKEKERIDEIRRLKQKREELMFSLQEAERRYDLARAADLRYGAIQEVESAIAQLEGTSSEENVMLTENVGPEHIAEVVSRWTGIPVTRLGQNEKERLIGLADRLHKRVVGQNQAVNAVSEAILRSRAGLGRPQQPTGSFLFLGPTGVGKTELAKALAEQLFDDENLLVRIDMSEYMEQHSVSRLIGAPPGYVGHEEGGQLTEAVRRRPYCVILFDEVEKAHVAVFNTLLQVLDDGRLTDGQGRTVDFRNSVIIMTSNLGAEHLLAGLTGKVTMEVARDCVMREVRKHFRPELLNRLDEIVVFDPLSHDQLRKVARLQMKDVAVRLAERGVALAVTDAALDYILAESYDPVYGARPIRRWMEKKVVTELSKMVVREEIDENSTVYIDAGAGDLVYRVESGGLVDASTGKKSDVLIHIANGPKRSDAAQAVKKMRIEEIEDDDNEEMIED
Protein: Large proline-rich protein BAG6 (BCL2-associated athanogene 6) (HLA-B-associated transcript 3) (A0A1U9X7A6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Nucleus {ECO:0000256|ARBA:ARBA00004123}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
Interaction partners:
Sequence:
MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
Protein: Probable zinc transporter protein DDB_G0291141 (Q54F34)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May be involved in zinc transport from the cytoplasm to either intracellular organelles or extracellular spaces.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable zinc transporter protein DDB_G0269332
Sequence:
MAGSLDDSIYNNGRSGGGGGGFKFSKGFNKDSISKRIIMMLFFSKGIRAWSCIILLYFLQSSISIISASFYMCLFSAIFSVVVEKPWNLLSSLRPSQIKKIIYHSIFNLLIIITWNSSIKFIGPIGSILASDYTFSTYPLIFNSLLQGNFLATDMSRGSIMLMIGYFLIPLFGISNRLDILGYTSSQVFMIGLFSLIVHNVLVLWKKTIVRSWNSGSSGGKNKLSSLGSCVSTIILFVFKLFEGFSSGSSGSDSINQVSYSQLFVIAIITFILYSLNQFIDDVSEKELTFNVLSKVSLTSSVIFGLLAALFIGFKDFFHPILILSFIFIINAIHILYSKSNDIQPMTFSNNMDGGNSSIKTYNSSGGGGGGSIINGNGSGNAIYYFEILKDVLRQIVDKPTSRRIFTFLVINLMFMFVEMAYGIWTNSLGLITDACHMFFDATALFIALVAEVISQWKQNDKYSYGYGRFQVLSGFVNGIFLIFIAVTILMESVERLLEPPEINTDKLLLVSVLGFIINLIGIFSFHGDHGHSHGGGGGHSHGGGEKKEKHHGHSHGGHGDHQQVTPILGEEKKKKRSVNIDGVFLHLLADTLGSVGVIVSSLIIQIWGYTLADPICSLLISILIFLSVLPLIANTAKTLLQCTPEPIQSSLYQINQFILSIDGVHNIISYHFWSHYDDMNIATLKIQLNETASSNSTLDTERIKKSISKYLNKDHNIHKCIIEFIPLLYNNNNQQQGNDVPLINHHIHNDIHHNHSSSSSSSSHHHRHN
Protein: Protein YIF1B (YIP1-interacting factor homolog B) (Q9CX30)
Organism: Mus musculus (Mouse)
Function: Functions in endoplasmic reticulum to Golgi vesicle-mediated transport and regulates the proper organization of the endoplasmic reticulum and the Golgi. Plays a key role in targeting to neuronal dendrites receptors such as HTR1A (By similarity). Also plays a role in primary cilium and sperm flagellum assembly probably through protein transport to these compartments.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:33103737}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:33103737}; Multi-pass membrane protein {ECO:0000255}. Note=Shuttles between the endoplasmic reticulum, the intermediate compartment and the Golgi apparatus. {ECO:0000250|UniProtKB:Q6PEC3}.
Interaction partners:
- Protein YIPF7
- Protein YIPF5
- Protein YIPF4
- Protein YIPF1
- Protein YIPF2
- 5-hydroxytryptamine receptor 1A
Sequence:
MHATGLAAPAGTPRLRKWPSKRRVPVSQPGMADPHQFFDDTSSAPSRGYGGQPSPGGLGYPPSSSDAAFLAAPMSNMAMVYGSSLAAQGKELVDKNIDRFIPVSKLKYYFAVDTVYVGKKLGLLVFPYLHQDWEVQYQQDTPVAPRFDINAPDLYIPAMAFITYILVAGLALGTQDRFSPDLLGLQASSALAWLTLEVVAILLSLYLVTVNTDLTTIDLVAFLGYKYVGMIGGVLTGLLFGKIGYYLVLAWCCVSIFVFMIRTLRLKILAQAAAEGVPVRGARNQLRMYLTMAVAAAQPVLMYWLTFHLVR
Protein: Amino acid transporter, putative (Q57WK8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MRATKKHPNDGKGATTDPFVDGSDPIPSEVAAFDPLQQEHVDVVKEVKPSLFAVLLEKFIPHGGLWSCALNLASATLGAGICSLPAGFNLSGIVMSCIYLVCVAVGTVYSLNLLAKVAVKTGSRNYGEAAKAVMGPLAGYYTAALMIVMCFGGSVAYIIIIGIILKAVLNRDGVPEYLKSESGNRLMTSMVWLVIILPMCIPKQVNSLRHLSFVGVMFIVYFSCVVIGHSINKIINEGVADGIVYMRTGNSALDGLSLFLFSFICQPNAFEIFREMKHRSPQRFTIYGTVGMSMCAVLYFLVGLFGYLEFGGDAIDTVLSLYDPGENVAVAIAYIGVAAKVCVAFALHIIPMRDALYHCTGWHVDTVPYWKHSLIVTSITLAALLMGLFIPKASTVFGLVGAFCGGHIGLVLPPLFYMYSGGFTREKVGNIDFFGTYLLLFVGVVAVVFGTVSTIYNTVP
Protein: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (EC 3.2.1.96) (Q8T8V2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
Sequence:
MDSLESKELTSISKVMENNEKASENDKITGIPTEEEEEEVVPVKKKRTEEGGGEIKEVACEKETVQREKCQDKNTCRCSQLEAEPIKDNRQLLEFRVRSRDIDWRQYVLPLDTSVRTTPVYLDRQADFVGSTRRQVTEDNRRELLVCHDMMGNYLEDRHFYSSQKYDDYRFVHWSAVDYFCYFSHDYVTIPPCGWLNAAHRHGVPVLGTFIVEATARLDEFLVSEESVESTVEALTRLCEHFGFEGWLVNVEVTVPLAKMPSLYRFVRQLTAATESRVPHGRVFWYDSVTDDGQLRWQNELNSRNAEFFRHSHGTLINYAWDEGHLERSAQQVRREQSPRHRVFMGLDVFGRSRKGGFHSWETMELIAKNGFSAGILAPGWTFETLNRFGYNIKNPRGDDQVNASFLARNEAWWSRIWPTLATHPYTSLPFFTDFCVGSGRAKFERGWRILGEDSPFFNLSRQSLQPSVPLGRNAMHHFDEAYSGGCSLLVTNYERAFRLFVTDFELDRGVLLLRYVFKIDGDAVGTMFDLLVRVTPLRRNDQDLHLFCGDYEGSIVAPQRCYLSPHESDLPSDLFRLHHDSSSLAAGWQMRDYLVKFDGPVRVQDIGVKYQRPSESSTDAKLGFVYVDGLTLEDLKDTWTDIPVYSKHMWNEQRA