wanglab/gogpt-training-data huggingface dataset:
Protein: Large ribosomal subunit protein uL15c (50S ribosomal protein L15, chloroplastic) (CL15) (P25873)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL4c
- Large ribosomal subunit protein bL9c
- Large ribosomal subunit protein uL24c
- Small ribosomal subunit protein uS9c
- Large ribosomal subunit protein uL6c
- Large ribosomal subunit protein eL21z/eL21y
- Large ribosomal subunit protein uL5c
- Large ribosomal subunit protein bL27c
- Large ribosomal subunit protein bL21c
- Large ribosomal subunit protein uL11c
Sequence:
MATPLSISSNPLTSRHCYRLHLSSTSFKGNVSVLGANPSQILSLKLNQTLKTRNQQQFARPLVVVSQTAATSSAVVAPERFRLDNLGPQPGSRKKQKRKGRGISAGQGASCGFGMRGQKSRSGPGIMRGFEGGQTALYRRLPKLRGIAGGMRSGLPKYLPVNIKDIETAGFQEGDEVSLETLKQKGLINPSGRERKLPLKILGTGELSMKLTFKARAFSTQAKEKLEASGCTLTVLPGRKKWVKPSVAKNQARADEYFAKKRAAAAEAATSEPAASA
Protein: RidA family protein (O07205)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MSASRTMVSSGSEFESAVGYSRAVRIGPLVVVAGTTGSGDDIAAQTRDALRRIEIALGQAGATLADVVRTRIYVTDISRWREVGEVHAQAFGKIRPVTSMVEVTALIAPGLLVEIEADAYVGSAVADRNSGAGPKDPSPAGG
Protein: Protein Vpx (Viral protein X) (X ORF protein) (P19508)
Organism: Simian immunodeficiency virus (isolate PBj14/BCL-3) (SIV-sm) (Simian immunodeficiency virus sooty mangabey monkey)
Function: Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
Subcellular location: Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG. {ECO:0000250}.
Interaction partners:
Sequence:
MSDPRERIPPGNSGEETIGEAFDWLDRTVEEINRAAVNHLPRELIFQVWRRSWEYWHDEMGMSVSYTKYRYLCLIQKAMFMHCKKGCRCLGGEHGAGGWRPGPPPPPPPGLA
Protein: Protein IRON-RELATED TRANSCRIPTION FACTOR 2 (OsIRO2) (Basic helix-loop-helix protein 56) (OsbHLH056) (Q0JFZ0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription activator that binds to the DNA motif 5'-CACGTGG-3' in the promoter of iron (Fe) deficiency-inducible genes as well as of genes involved in iron homeostasis, thus contributing to basal tolerance to iron deficiency, iron uptake from soil and iron transport, particularly during seed maturation and germination. Promotes the accumulation of mugineic acid family phytosiderophores (MAs). Required for ethylene-mediated signaling during iron deficiency responses. Improves growth and yield, especially in calcareous soil with low iron availability. Promotes iron concentration in shoots and grain.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:31574173}. Cytoplasm {ECO:0000269|PubMed:31574173}. Note=Localized partially to the nucleus under iron deficiency conditions. {ECO:0000269|PubMed:31574173}.
Interaction partners:
- Transcription factor BHLH156
Sequence:
MEQLFVDDPAFASSMSSLEADIFSGAGQLPSSPWLDLDLDDDVQDLSMAPTTANAVSSGYGSGGSGSHRKLSHNAYERDRRKQLNELYSSLRALLPDADHTKLSIPTTVSRVLKYIPELQKQVENLERKKKELTTTSTTNCKPGVLGSQLMSEGMAPIVSATCINDMEIMVQVSLLSNVAGSVLPLSKCIKVLENEGLHFISSSTSSGFGNRTFYSIHLQRSEGTINEECPAFCERLEKVVRNKAKL
Protein: Cellular retinoic acid-binding protein 1 (Cellular retinoic acid-binding protein I) (CRABP-I) (P29762)
Organism: Homo sapiens (Human)
Function: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11909957}.
Interaction partners:
- Cytochrome P450 26C1
- Cytochrome P450 26A1
- Retinoic acid receptor alpha
- Retinoic acid receptor beta
- Voltage-dependent T-type calcium channel subunit alpha-1G
- Cytochrome P450 26B1
- Neurogenin-1
- Arginine--tRNA ligase, cytoplasmic
Sequence:
MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLATWENENKIHCTQTLLEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE
Protein: Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Death-associated protein 5) (DAP-5) (p97) (P78344)
Organism: Homo sapiens (Human)
Function: Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
Interaction partners:
- Eukaryotic translation initiation factor 4E
- Eukaryotic initiation factor 4A-II
- Eukaryotic initiation factor 4A-I
- YTH domain-containing family protein 3
- Eukaryotic translation initiation factor 4 gamma 1
- Eukaryotic translation initiation factor 4B
- Eukaryotic translation initiation factor 4E type 1B
- Eukaryotic translation initiation factor 4 gamma 3
- Eukaryotic translation initiation factor 4E type 2
- Eukaryotic translation initiation factor 4H
Sequence:
MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD
Protein: von Hippel-Lindau tumor suppressor isoform 1 (von Hippel-Lindau tumor suppressor, isoform CRA_d) (A0A0S2Z4K1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD
Protein: TGFB induced factor homeobox 2 (H0YKN5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLAVSVPAPTNVLSLSVCSMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLLTRAEAGS
Protein: Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA) (Q80TL0)
Organism: Mus musculus (Mouse)
Function: Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42 (By similarity). Dephosphorylates PRKAA2.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8WY54}. Cytoplasm {ECO:0000250|UniProtKB:Q8WY54}. Note=A truncated form, major form, with the C-terminal part missing, is mostly found in the cytoplasm and a little in the nucleus. The full-length, minor form, is found in the nucleus. {ECO:0000250|UniProtKB:Q8WY54}.
Interaction partners:
Sequence:
MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPESEPEPEPEAELVAAEAAEASGEEPGEDAATVEATEEGEQDQDPEPEDEAVEEETATEGEEEEEEEAAAPGHSAVPPPPQPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHCIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQIYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESEWTENSFQGGQEDGGDDKETHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSPGPQINVLEDPDYLDLTQIEASKPHSTQFLPPVEMIGPGAPKKDLNELIMEERSVKSSLPERSGAGEPRVSFNLGSTGQQICRMENLSPVSSGLENEQFKSRGKTASRLYHLRHHYSKRQRGFRFNPKFYSFLSAREPSHKIGISLSSLTRSGKRNKMLRSSLPWRENSWEGYSGNVKIRKRNDIPCPDFPWSYKI
Protein: Zinc finger protein 804A (Q7Z570)
Organism: Homo sapiens (Human)
Interaction partners:
- Disrupted in schizophrenia 1 protein
- D-amino acid oxidase regulator
- Dysbindin
- Catechol O-methyltransferase
- Neurogranin
Sequence:
MECYYIVISSTHLSNGHFRNIKGVFRGPLSKNGNKTLDYAEKENTIAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKDERKQEKALQRLHKLAELRKETVCAPGSGPMFKSTTVTVRENCNEISQRVVVDSVNNQQDFKYTLIHSEENTKDATTVAEDPESANNYTAKNNQVGDQAQGIHRHKIGFSFAFPKKASVKLESSAAAFSEYSDDASVGKGFSRKSRFVPSACHLQQSSPTDVLLSSEEKTNSFHPPEAMCRDKETVQTQEIKEVSSEKDALLLPSFCKFQLQLSSDADNCQNSVPLADQIPLESVVINEDIPVSGNSFELLGNKSTVLDMSNDCISVQATTEENVKHNEASTTEVENKNGPETLAPSNTEEVNITIHKKTNFCKRQCEPFVPVLNKHRSTVLQWPSEMLVYTTTKPSISYSCNPLCFDFKSTKVNNNLDKNKPDLKDLCSQQKQEDICMGPLSDYKDVSTEGLTDYEIGSSKNKCSQVTPLLADDILSSSCDSGKNENTGQRYKNISCKIRETEKYNFTKSQIKQDTLDEKYNKIRLKETHEYWFHKSRRKKKRKKLCQHHHMEKTKESETRCKMEAENSYTENAGKYLLEPISEKQYLAAEQLLDSHQLLDKRPKSESISLSDNEEMCKTWNTEYNTYDTISSKNHCKKNTILLNGQSNATMIHSGKHNLTYSRTYCCWKTKMSSCSQDHRSLVLQNDMKHMSQNQAVKRGYNSVMNESERFYRKRRQHSHSYSSDESLNRQNHLPEEFLRPPSTSVAPCKPKKKRRRKRGRFHPGFETLELKENTDYPVKDNSSLNPLDRLISEDKKEKMKPQEVAKIERNSEQTNQLRNKLSFHPNNLLPSETNGETEHLEMETTSGELSDVSNDPTTSVCVASAPTKEAIDNTLLEHKERSENINLNEKQIPFQVPNIERNFRQSQPKSYLCHYELAEALPQGKMNETPTEWLRYNSGILNTQPPLPFKEAHVSGHTFVTAEQILAPLALPEQALLIPLENHDKFKNVPCEVYQHILQPNMLANKVKFTFPPAALPPPSTPLQPLPLQQSLCSTSVTTIHHTVLQQHAAAAAAAAAAAAAGTFKVLQPHQQFLSQIPALTRTSLPQLSVGPVGPRLCPGNQPTFVAPPQMPIIPASVLHPSHLAFPSLPHALFPSLLSPHPTVIPLQPLF
Protein: Uncoordinated 115a, isoform F (A0A0B4LI11)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MYILIYISIPKHPQTDKTRPIYPSTLGTELRTELGKTGQGKQKIYCAKCTKKCSGEVLRVADNHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKCANCQQYVEGEVVSTMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAESPTRATAHQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRCKACQAVLNGEYMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYLQGSAIWHPRCGPGPSESGIILNGGGGTSSVVGGASNGNFTDTECDRMSSSALSEMHYRTVSPGLILREYGRPNAEDISRIYTYSYLTDAPHYLRKPIDPYDKTPLSPHFHRPSSYATTASNAGSVAGSRPPSRPHSRTRSAMKVLVDAIRSETPRPKSPGMNNEEPIELSHYPAAKKPPPGEQPKIERDDFPAPPYPYTDPERRRRYSDTYKGVPASDDEDENVENGKPNGKVKNGEEQQRLQREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNASRTPSASKEPLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSYRSPPKPGYGFKTTTLPYIRNGFSSDFSYGGLGDKTHSTDLSCGKSEASVDSITEGDRRALMGGDLPASSTYSGALSYHYPQAGLIRRSLPNMSHSMLVHEPAKIYPYHLLLITNYRLPSDVDRCNLERHLSDIEFEHILQCARSEFYRLPQWRRNELKRRVKLF
Protein: LD09351p (Q95RV7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASVESYYRVSNLVSTPGGHIEQRAESPGDNETSTEAEVIGQLNFIRDKILAKQDQHLHHYLQKMEIPLHIFGIRWLRLLFGREFMLLDLLLLWDAIFADSDRFDLPNYILVAMLVHIRDKLLLSDYTTSLTYLMRYPNNVDVHLVLRHALFMLNPKQFEYPPNAFTCVSFANSSADKDVPPPAGQRPRTNSENSSMATSGSQIDRQITFMQERNAADSSALAKLQDTHRVAMDGYLENSPELLRLELKNAQTVIKIARSKLQSYLSTVRHHVGKQANGSEELGRTLDGIEELCSFLDVKFMFPLHQRSAPIDQALEANEQKQLNTVSKPPKPTASSTPANAPAALSATGGYQMPENAFMHSSMRRLLGELREIELSTITSDEKPGNAVVQNGLPAAEPQQRHRNESS
Protein: Interferon gamma receptor 1 (Q6P6T3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Interferon gamma
- Interferon gamma receptor 2
- Tyrosine-protein kinase
- Tyrosine-protein kinase JAK2
- Signal transducer and activator of transcription 1
- Interferon alpha/beta receptor 1
- Interferon alpha/beta receptor 2
- Tyrosine-protein kinase
- Suppressor of cytokine signaling 1
- Interferon beta
Sequence:
MILLVVLMLSAEIGSGALMSTEDPKPPSVPAPTNVLITSYDLNPVVHWKHQNVSQAAVFTVQVKMYPDNWTDACTNIAHHYCNIYKHISYPDSSAWARVKAKVGQRESAYAQSEEFIMCRKGKVGPPGLDIGRKEDQLIVHIFHPKVNVSQETMFGDGNTCYTFDYTVFVKHYRSGEILHTEHSVLKEDCSETLCELNISVSTLNSNYCVSVVGKSSFWQVNTETSKDACIPFLHDDREESIWMLLVAPLLFLTIVVPALVCCYIKKNPFKRKSIMLPKSLLSVVKNATSETKPESKYSLVTSCQPAVLENETVICEEHLSTVTTPDSLEAPEQEELSKGTVATVAEGNTSPETTDSPPTPVQSGHFSLSSSNQSGSCSLTTYHSRDGSDSGLVGTGSSISDSDFLPNNDSETKMADPAPTPVRKALTFSGYDKPHVLVDVPVDGEGKESLIGYRLTGDTQELS
Protein: Latent-transforming growth factor beta-binding protein 4 (LTBP-4) (Q8K4G1)
Organism: Mus musculus (Mouse)
Function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q8N2S1}.
Interaction partners:
- Transforming growth factor beta-1 proprotein
Sequence:
MRRPGLGGPCPLLLLLLLPAATSASGSSPSPSPSPIEKAVVPSHQAGVAACHCCLDQTPKSSRCTRASCRVRNCPPAKCTGLEGCLTPTPSVPSPSRSPVEKSQVSLNWQPLTLQEARALLRQRRPRGPWARALLKRRPPHRAPAGQARVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAMPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEANPEALARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGSECASPLPGLRTQEVCCRGEGLAWGVHDCHPCAEHLRNSNQVSGPNGPCPPGFERVNGSCVDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCYRVLHDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPYGSEGFREICPAGPGYHYSASDLRYNTRPLNQDPPRVTFNQPRVPPATPRPPTGFLPTRRPEPRPDPGPQPEPRPRPEPRPRPESRPRPEPRPRPEPRPQPESQPRPESRPRPESQPWPEFPLPSIPAWTGPEIPESGPSSSMCQRNPQVCGPGRCVPRPSGYTCACDPGFRLGPQGTRCIDIDECRRVPTPCAPGRCENTPGSFRCVCGTGFQAGPRATECLDVDECRRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGVCENLPGSFRCVCPAGFRGSACEEDVDECAQQPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECSRSPSPCAYGRCENTEGSFKCVCPTGFQPNAAGSECEDVDECENRLACPGQECVNSPGSFQCRACPVGHHLHRGRCTDVDECSSGTPCGLHGQCTNTKGSFHCSCSTGYRAPSGQPGPCADINECLEGDFCFPHGECLNTDGSFTCTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHPGPEGTCDDIDECREYGSAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAMCQNLPGSFQCVCDQGYEGARDGRHCVDVNECETLQGVCGSALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRAPAGTFPGSQPQAPASPSLPARPPAPPPPRRPSPPRQGPVSSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLVPSGDLSARRDVDECQLFQDQVCKSGVCVNTAPGYSCYCSNGFYYHAHRLECVDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGPDLVCSRPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGIPYEYGPDIGPPYQSLPYGPDLYPPPVLPYDPYPPPPGPFARREAPYGAPPFDMPDFEDDGGPYGESETPDPPSRGTGWPYRSRDTRGSFPEPEESSERGSYTGALSEPYEGLEAEECGILDGCPHGRCVRVPEGFTCDCFDGYRLDITRMSCVDVNECDEAEATSPLCVNARCVNTDGSFRCICRPGFAPTHQPHHCAPARPRA
Protein: Disintegrin lebein-1-alpha (ML-3) (MS-II) (Platelet aggregation activation inhibitor) (P83253)
Organism: Macrovipera lebetinus (Levantine viper) (Vipera lebetina)
Function: Strongly inhibits ADP-induced platelet aggregation on human platelet-rich plasma. Also avidly binds to the laminin-binding beta-1 integrins (alpha-3/beta-1, alpha-6/beta-1, and alpha-7/beta-1) in an RGD-independent manner.
Subcellular location: Secreted {ECO:0000269|PubMed:11343790}.
Interaction partners:
Sequence:
MIQVLLVTICLAVFPYQGSSIILESGNVNDYEIVYPKKVTVLPTGAMNSGNPCCDPVTCKPRRGEHCVSGPCCRNCKFLNAGTICNRARGDDMNDYCTGISSDCPRNPYKD
Protein: ATP-dependent DNA helicase DinG (EC 5.6.2.3) (DNA 5'-3' helicase DinG) (P27296)
Organism: Escherichia coli (strain K12)
Function: DNA-dependent ATPase and 5'-3' DNA helicase. Can also unwind DNA-RNA hybrid duplexes. Is active on D-loops and R-loops, and on forked structures. May be involved in recombinational DNA repair and the resumption of replication after DNA damage. The redox cluster is involved in DNA-mediated charge-transport signaling between DNA repair proteins from distinct pathways. DinG cooperates at long-range with endonuclease III, a base excision repair enzyme, using DNA charge transport to redistribute to regions of DNA damage.
Interaction partners:
- DNA helicase II
- Putative DNA repair helicase RadD
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit omega
- Protein RecA
- Uncharacterized protein YbiB
- Transcription-repair-coupling factor
- DNA polymerase I
- ATP-dependent DNA helicase RecG
Sequence:
MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQLDLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR
Protein: Small ribosomal subunit protein uS7y (40S ribosomal protein S5-2) (AtRPS5A) (Protein ARABIDOPSIS MINUTE-LIKE 1) (P51427)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein eS1z
- Small ribosomal subunit protein eS28z/eS28y
- Small ribosomal subunit protein uS12z
- Small ribosomal subunit protein uS15y
- Small ribosomal subunit protein uS13z/uS13y/uS13x
- Small ribosomal subunit protein eS6y
- Small ribosomal subunit protein eS28x
- Small ribosomal subunit protein uS9y
- Small ribosomal subunit protein eS6z
- Small ribosomal subunit protein uS14z/uS14y/uS14x
Sequence:
MATAADVDAEIQQALTNEVKLFNRWTYDDVTVTDISLVDYIGVQAAKHATFVPHTAGRYSVKRFRKAQCPIVERLTNSLMMHGRNNGKKLMAVRIVKHAMEIIHLLSDLNPIQVIIDAIVNSGPREDATRIGSAGVVRRQAVDISPLRRVNQAIFLITTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDEIERVAKANR
Protein: Class III chitinase ChiA2 (EC 3.2.1.14) (Q4WB15)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Secreted, cell wall {ECO:0000256|ARBA:ARBA00004191}.
Interaction partners:
Sequence:
MYFTTLLSALSLMAAAASALPHQLSSRASGAQNVVYWGQNGGGTVENNDLASYCTSTSGIDIIVLSFLYQYGNGNTIASGTIGQSCYISPSGQPQNCDALASAIKTCQSRGVKVILSLGGAVGAYSLSSQAEAETIGQNLWEAYGNTQGNGNVPRPFGSTFVNGWDFDIESYSGNEYYQYLINKLRSNFASDPSNQYYITGAPQCPIPEPNMQVIVTKAQFDYLWVQFYNNPGCSVNGPINYDQWVSNLANTPSANAKIFIGVPASPLGATGTSSGAQYYLQPSALASLVAEYKDNPAFGGVMMWSAGFSDANVNNGCTYAQEAKRILTTGSPC
Protein: CRISPR system Cascade subunit CasC (Q46899)
Organism: Escherichia coli (strain K12)
Function: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
Interaction partners:
- CRISPR system Cascade subunit CasE
- CRISPR system Cascade subunit CasD
- CRISPR system Cascade subunit CasB
- CRISPR-associated endoribonuclease Cas2
- CRISPR system Cascade subunit CasA
- CRISPR-associated endonuclease/helicase Cas3
- CRISPR-associated endonuclease Cas1
- Crossover junction endodeoxyribonuclease RuvC
- DNA-binding transcriptional dual regulator CRP
Sequence:
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGEA
Protein: Collagen, type XVII, alpha 1a (B8A4S4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDKLTTTKIVKVEGGSGGSGKEIQKHTETVTTTRLTSLPPKAHSGQQILTSIGNGSGSAGGAVLLEKKFITHSSAEGGASRSYVISSSSSGSSASSSSGAGSVISGFDGISGEISVTGPITSSTVKSSTSAVKSSSVVSTSITSSSAAGGELSSGYGSISSSSSEFVSGSSGGSISTSEGSMSKSRSGGGSSAVMSGEGTSSSKTVSKFSSSSPSGTRKGLSYSTVPTERKTIMNITTGGYEGSSSGNSSPEYIKKDSAATRGRTQTRESEIRARLQSASPSARWTELDDVKRLLKGSRSGSISPPRSPTSTLPIPKKASIDVRHESQSGFDGTVLDAGFSGYYTNPNNLSYTTLQQPSSPTGGMQNNLTLSSSALDTTVYGMQNNLSTSGGAMMANGRCTGYVYGVPKNVGSAGLATTISAIPSSPITADDVFMKDGKLIAIGKENVAAKTETERLIMSKNTGKQFVPSSFNAGADTFSEDSLKREKKMISSATDPQTTTITGSKSSTKNKATYADIRKDDSDGAGCGFWTCCSWWKWLLALLFALLLLLGLLCGLIALGEQLRRLKARVDAIDGGGTSPRTSGLKTDDIPGVQSGNTINLGYEPAGQDSLILQRAILRELQSDTIRASLATSLRGERGEPGPKGDQGPPGVKGDSGFPGIPGPPGLIGHPGQEGPRGPKGSAGESGSDGLPGPRGREGPAGPRGEPGPPGIGEKGEKGSFGDVGAPGIAGPPGPVGPKGDAGAQGVPGLTGAPGPQGFRGDSGDPGPKGDKGPAGPPGVKGDQGERGPRGATGEPGQPGPAGPPGEKGLKGSTGAPGPDGVKGLRGDQGPVGLPGARGPSGPPGDSGIPGTPGLQGPPGLPGTPGQPGAKGEAGEPGRVISAGANANTVAVSGPPGPPGAPGPAGPPGLSGPIGPAGLPGSPGAKGDKGDKGEDGKPGVTESAGKKSEAGEPGPPGPPGPPGPPGDDGKPGVGEPGPAGPPGEKGEPGSFVPTSETFFAGPPGPPGPIGPKGSQGDVGPQGFPGQPGLPGEPGIGIPGQPGSPGPRGEQGLDGPLGPQGPQGPMGPMGPEGPKGDAGVPGAPGIPGYSYGGGSRSAPGPPGPPGPPGPPGEPGSQGDGSPNAVQQISDYLRSEPIRQYLAGPPGPPGPPGPSGSASDDALASRVIEYLQRDEVRQYLIGPPGPPGPPGVPGGYGFNTQEVAGRVMSLINDAGFRGLPGPPGPPGPQGPPGNSGGLVSYAANENQQHIRAEPQEYIKSHPRADENLDYTAIAKQVSDYIKAHGLLNGNAGFPGAPGRQGYPGPPGFPGEPGTPGQPGPPGQAGPPGLPGPPGLDTVHNYSNMTAVLDYIKENHMKGQKGDLGFPGIPGSPGIDGKQGIVGLPGIKGQKGERGEATYVNRRRRRSTVI
Protein: NADP-dependent alcohol dehydrogenase C (EC 1.1.1.2) (P9WQC5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Aldehyde dehydrogenase
- Probable aldehyde dehydrogenase
- Probable aldehyde dehydrogenase
- aldehyde dehydrogenase
- Probable aldehyde dehydrogenase NAD dependent AldA
- Glycerol kinase
- D-glycerol 3-phosphate phosphatase
Sequence:
MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAIDIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTKYRQGDRVGVGCFVDSCRECNSCTRGIEQYCKPGANFTYNSIGKDGQPTQGGYSEAIVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRVAIIGLGGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADPDTFRKLRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFALALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLASDVRYRFVIDISAL
Protein: Serine protease inhibitor Kazal-type 13 (D3ZVP0)
Organism: Rattus norvegicus (Rat)
Function: May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction.
Subcellular location: Secreted {ECO:0000269|PubMed:23430248}. Note=Secreted into the lumen of the initial segment of the epididymis and binds to sperm. In the initial segment of epididymis, localizes on the dorsal surface of the acrosomal region of sperm, gradually becomes more restricted to the acrosomal region in spermatozoa during epididymal transit.
Interaction partners:
- Serine protease inhibitor Kazal-type 14
- Serine peptidase inhibitor, Kazal type 10
- Serine peptidase inhibitor, Kazal type 9
Sequence:
MTRRGCWPHRIIFSLILLTWTHVTLAALIRSHTFSNWPKPPCKMYYPIDPDYEANCPDVIALVCATNGLNYKNECFFCIDRWEFGPHIEFVKYGKCE
Protein: Glutamate receptor (Q38PU0)
Organism: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104, ECO:0000256|RuleBase:RU367118}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104, ECO:0000256|RuleBase:RU367118}.
Interaction partners:
Sequence:
MPAELLLLLIVAFASPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLILRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWWEGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLY