wanglab/gogpt-training-data huggingface dataset:
Protein: receptor protein-tyrosine kinase (EC 2.7.10.1) (E9PSY0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Growth arrest-specific protein 6
- Proto-oncogene tyrosine-protein kinase Src
- Vitamin K-dependent protein S
- SHC-transforming protein 1
- GRB2-associated-binding protein 1.
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Tyrosine-protein kinase
- SHC-transforming protein 3
- Tyrosine-protein kinase JAK2
Sequence:
MGRVPLAWCVALCCWGCAAPKDTQTEADSPFVGNPGNITGARGLTGTLRCELQVQGEPPEVMWLRDGQILELADNTQTQVPLGEDWQDEWKVVSQLRISALQLSDAGEYQCMVHLEGRTFVSQPGFVGLEGLPYFLEEPEDKAVPANTPFNLSCQAQGPPEPVTLLWLQDAVPLAPVAGYSFQHSLQAPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQRPHNLHVVSRHPTELEVAWIPSLSGIYPLTHCTLQAVLSDDGVGVWLGESDPPEEPLTVQVSVPPHQLRLEKLLPHTPYHIRVSCTSSQGPSPWTHWLPVETTEGVPLGPPENVSAMRNGSQALVRWQEPREPLQGTLLGYRLAYRGQDTPEVLMDIGLTREVTLELRGDRPVANLTVSVAAYTSAGDGPWSLPVPLEPWRPGQGQPLHHLGHTPVSLPCHSHLGPRELDPGTLAVICPPYPLTVSEPPPPAFSWPWWYVLLGALVAAACVLILTLFLVHRRKKETRYGEVFEPTVERGELVVRYRARKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPLDCLDGLYALMSRCWELNPRDRPSFAELREDLENTLKALPPAQEPDEILYVNMDEGGSHLEPRGAAGGADPPTQPDPKDSCSCLTEADVHSAGRYVLCPSTAPGPTLSADRGCPAPPGQEDGA
Protein: Heat shock 70kDa protein (Q5KT34)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MSSAKGPSIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFNDQVVQADMKHWPFKVVSDGGKPKVQVDYKGENKCFNPEEISSMVLVKMREIAEAYLGQKVSNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGMDKGMSRERNVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRALRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEEMCSDLFRRTLEPVEKALGDAKMDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAIQAAILSGDKSENVQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPSKQTQTFTTYSDNQPGVMIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQDADKYKAEDDAQREKIAAKNSLESYAFNMKSSVEDDNMKGKISQEDKKKVVDRCDQTISWLENNQLGDKEEYEHQLKELEKVCQPIITKLYQQGGMPTGCCGDQARTSSGDSSQGPTIEEID
Protein: Protein SEC13 homolog (Q7ZYJ8)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Lysosome membrane {ECO:0000256|ARBA:ARBA00004656}. Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
- Uncharacterized protein
- Nuclear pore complex protein Nup155
- Uncharacterized protein.
- Nuclear pore complex protein Nup133
- Uncharacterized protein
- Uncharacterized protein.
- Nuclear pore complex protein
- Nuclear pore complex protein Nup85
- Nucleoporin Nup37
- WD_REPEATS_REGION domain-containing protein.
Sequence:
MVSVINTVDTSHEDMIHDAQMDYYGIRLATCSSDRSVKIFDVKNGGQILIADLRGHDGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTYEYTGHDSSVNSVCWAPHDFGLVLACGSSDGAISILTFTGDGPWEVKKISNAHTIGCNAVSWAPSVIPGSLVDQPSSQKPNYIKRFVSGGCDNLVKIWREEDGQWKEDQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVYIWTSDDAATNCWTPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWACISDVNKGQGAVSTVTEGQLNDQ
Protein: Truncated Kidins220 isoform m5 (A0A076N1C3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
VRAAREQINIGGLAYPPLPLHEAPPRPPSGYSQPASVCSSSASFNGPFPGGVVSPQPHSSYYSGLSGPQHPFYNRLCDSGFNKQRQASVPATGTSLLLSSMTVDIVCEKLRQIEGLDQGMLPQYCTTIKKANINGRVLAQCNIDELKKEMAMNFGDWHLFRSMVLEMRSVENQVVPEDPRFLNENSSAPVAHGESARRTSHSELPHTELSSQTPYTLNFSFEELNTLGLDEGAPRHSNLSWQSQTRRTPSLSSLNSQDSSIEISKLTDKVQAEYRDAYREYIAQMSQLEGGTGSSTISGRSSPHSTYYIGQSSSGGSIHSNLEQERGKENELKQEEGRKSFLMKRGDVLDYSSSGVSTNEASPLDPITEEDEKSDQSGSKLLPGKKSSERPSLFQTDLKLKGSGLRYQKLPSDEDESGTEESDNTPLLKDDKDKKAEGKAERVAKSPEHSVEPIRTFIKAKEYLSDALLDKKDSSDSGVRSNESSPNHSLHNEAADDSQLEKANLIELEDEGHSGKRGMPHSLSGLQDPVIARMSICSEDKKSPSECSLIASSPEESWPSCQKAYNLNRTPSTVTLNNNTAPTNRANQNFDEIEGVRETSQVILRPGPSPNPTAVQNENLKSMAHKRSQRSSYTRLSKDASELHAASSDSTGFGEERESIL
Protein: Several ankyrin repeat protein transcript variant 2 (A1DRY3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
WRINGLHGHSGAESRERVSDDGERKCEESDRRSRVAAGSLSADAGFSRSDLRRVSENLGHCRSVSRERVRGDSGHSHSCSWERVRGDSTFCSSDVNFSEVGGHQTTDSRGTAREDRGLRLSGPWEGVSDIRDPRTSDFGDRVSDDRSRRFSGSWEGGSVEGGHSVGSSWEEVSGDRGYAASDSSGVSGSEDASYRFSGFWERESEDEGFRCSFWERAREDLGPRPSDDGEEGRCRCSGSWVRASEDRRSIRGLDSTPPQSRRCCAMPGVANSGPSTSSRETANPCSRKKVHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSGDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLLEELQKYDIDDENEIDENDVKYFIRHGVEGSTDAKDDLCLSDLDKTDARMRAYKKIVELRHLLEIAESNYKHLGGITEEDLKQKKEQLESEKTIKELQGQLEYERLRREKLECQLDEYRAEVDQLRETLEKIQVPNFVAMEDSASCESNKEKRRVKKKVSSGGVFVRRY
Protein: Hdac5 protein (Q5RJZ2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYDDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPSINAVATLEKVIEIQSKHWSCVQRFATGLGCSLREAQTGEKEEAETVSAMALLSMGAEQAQAAATQEHSPRPAEEPMEQEPAL
Protein: Transcription initiation factor TFIID subunit 10b (Transcription initiation factor TFIID 16 kDa subunit) (TAFII-16) (TAFII16) (dTAF(II)16) (Q9XZT7)
Organism: Drosophila melanogaster (Fruit fly)
Function: TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10669741}. Nucleus {ECO:0000269|PubMed:10669741, ECO:0000269|PubMed:11134347}.
Interaction partners:
- Transcriptional adapter 1-2
- SAGA factor-like TAF6
- Transcriptional adapter 2b
- Transcription initiation factor TFIID subunit 6
- Protein will decrease acetylation
- Transcription initiation factor TFIID subunit 12
- SAGA-associated factor 29kDa
- Transcription initiation factor TFIID subunit 9
- SAGA complex subunit Spt3
- Transcription initiation factor TFIID subunit 11
Sequence:
MVGSNFGIIYHNSAGGASSHGQSSGGGGGGDRDRTTPSSHLSDFMSQLEDYTPLIPDAVTSHYLNMGGFQSDDKRIVRLISLAAQKYMSDIIDDALQHSKARTHMQTTNTPGGSKAKDRKFTLTMEDLQPALADYGINVRKVDYSQ
Protein: Candida glabrata strain CBS138 chromosome J complete sequence (Q6FNU3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Carbon catabolite-derepressing protein kinase
- Glucose transport transcription regulator RGT1
Sequence:
MTIISEDEKSVARDREGVLARAIKVVNRKFRRKDVRREKLERALSCDNQMTLNSTNLYAAQQQEYQRREENDIEENQEPEGGNDDIDYDISILSDEMSTVDDASLLFAEPPQKQSHMMSIVVGAFVAVGGFLFGYDTGLINSIVDMRYVRENIAPNHVGFTAQQLAILVSFLSLGTFVGALSAPVISDKYGRKKTIMFSTAVVFSLGNSLQVGAHNIQLLIAGRVISGLGVGLVSAVVPLYQAEAAHKSLRGAIISTYQWAITWGLLVSSAVSQGTHNRNDASSYRIPIGLQYVWAYILAAGMLWLPESPRYYVLRDQLDKAAQSLSFLRGVPIHDSGLLEELVEIKATFDYESSFGKTTFWDCFKSNKSRPKQTLRMFTGIAIQAFQQFSGINFIFYYGVSFFNRSGVENSYIVSLITYAVNVGFSVPGMFLVEYFGRRSVLLYGGAIMTLSNFIIAIVGSSTQSVVANKVMIAFICLFIASFAATWGGVVWVISAELYPLGVRAKCTAICAAANWLINFVCAFITPYIVDTGERRALIGPKIYFIWGSLNALGILVVYFTVYETRGLTLEEIDELYTKSPNGIVSAKWNRRIRHREKTYGHKEQQNRDRNQQTTKENLRKNVVNEDMLSDDLTPRNDSINTHHSVDSNEKYQSENTDNTLAPAVNDRSMMDFGNDMILHICNRGPPSISTAASVEEFGGNSTQMENLSYNESNSVEKKKVGLFSKFKLGSRKSSINGTEEDSKPKSPQLGQAEFSPSPLDVKVSDDDHNDFVDLGNGFGLYSVTRRLSSGVPDTSDEESAYDLGNAPSSTNTYRNRGNLDSINTYMSQLIQSNTYTSQNTGYSQNDNDQTQHHQ
Protein: Glucoamylase (EC 3.2.1.3) (1,4-alpha-D-glucan glucohydrolase) (Glucan 1,4-alpha-glucosidase) (P36914)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Interaction partners:
- Glycosyl hydrolase family 13 catalytic domain-containing protein
- Glycosyl hydrolase family 13 catalytic domain-containing protein
- alpha-amylase
- Alpha-amylase A type-1/2
- Alpha-glucosidase
- Glycosyl hydrolase family 13 catalytic domain-containing protein
- Alpha-1,4 glucan phosphorylase
- Probable alpha/beta-glucosidase agdC
- 1,4-alpha-glucan-branching enzyme
- Glycogen debranching enzyme
Sequence:
MVSFSSCLRALALGSSVLAVQPVLRQATGLDTWLSTEANFSRQAILNNIGADGQSAQGASPGVVIASPSKSDPDYFYTWTRDSGLVMKTLVDLFRGGDADLLPIIEEFISSQARIQGISNPSGALSSGGLGEPKFNVDETAFTGAWGRPQRDGPALRATAMISFGEWLVENGHTSIATDLVWPVVRNDLSYVAQYWSQSGFDLWEEVQGTSFFTVAVSHRALVEGSSFAKTVGSSCPYCDSQAPQVRCYLQSFWTGSYIQANFGGGRSGKDINTVLGSIHTFDPQATCDDATFQPCSARALANHKVVTDSFRSIYAINSGRAENQAVAVGRYPEDSYYNGNPWFLTTLAAAEQLYDALYQWDKIGSLAITDVSLPFFKALYSSAATGTYASSTTVYKDIVSAVKAYADGYVQIVQTYAASTGSMAEQYTKTDGSQTSARDLTWSYAALLTANNRRNAVVPAPWGETAATSIPSACSTTSASGTYSSVVITSWPTISGYPGAPDSPCQVPTTVSVTFAVKATTVYGESIKIVGSISQLGSWNPSSATALNADSYTTDNPLWTGTINLPAGQSFEYKFIRVQNGAVTWESDPNRKYTVPSTCGVKSAVQSDVWR
Protein: Hydrogenase maturation factor HypA (P0A700)
Organism: Escherichia coli (strain K12)
Function: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Mediates transfer of nickel, but not zinc, from the low-affinity metal-binding site in the GTPase domain of HypB to HypA. HypA is involved in maturation of hydrogenase 3. It may partially substitute for the function of HybF and vice versa. May act as a scaffold for assembly of the nickel insertion proteins with the hydrogenase precursor protein after delivery of the iron center.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:22016389}.
Interaction partners:
- Hydrogenase maturation factor HypB
- Hydrogenase maturation factor HypC
- Hydrogenase maturation factor HypD
- Carbamoyl dehydratase HypE
- Carbamoyltransferase HypF
- Formate hydrogenlyase subunit 5
- Hydrogenase-1 large chain
- FKBP-type peptidyl-prolyl cis-trans isomerase SlyD
- Hydrogenase 3 maturation protease
- Hydrogenase-2 large chain
Sequence:
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE
Protein: Uncharacterized protein (Q38BJ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFLRPIALPLWVLFVTVATFFVLRALDPVDVGAHREKVYGLPPQVVWLFPLVPVCVWLCYEAIMLMAPAGSKVALKVYD
Protein: 26S proteasome regulatory particle triple-A ATPase subunit4 (Os02g0199900 protein) (Q9FXT8)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- Os03g0851300 protein
- 26S proteasome regulatory particle non-ATPase subunit12
- 26S protease regulatory subunit 4, putative, expressed
- 26S proteasome regulatory subunit 7A
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- 26S proteasome regulatory subunit 4 homolog
- Os06g0600100 protein
- 26S proteasome regulatory particle triple-A ATPase subunit6
- Proteasome subunit alpha type-5
- 26S proteasome regulatory particle non-ATPase subunit11
Sequence:
MADGEDAAAARRRASVTEYRKKLLNCRELESRVSTVRENLKNAKKDFTKTEDDLKSLQSVGQIIGEVLRPLDNERFIVKASSGPRYVVGCRSKVDKEKLTSGTRVVLDMTTLTIMRTLPREVDPVVYNMLHEDPGNVSYSAVGGLSDQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKIVSSAIIDKYIGESARLIREMFGYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDELGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQARMEVLKIHAAGIAKHGEIDYEAVVKLAEGFNGADLRNVCTEAGMAAIRAERDYVVHEDFMKAVRKLNDAKKLESSAHYSADFGKE
Protein: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI (RPnTP synthase subunit PhnI) (EC 2.7.8.37) (Ribose 1-methylphosphonate 5-triphosphate synthase nucleosidase subunit) (P16687)
Organism: Escherichia coli (strain K12)
Function: Together with PhnG, PhnH and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. PhnI alone has nucleosidase activity, catalyzing the hydrolysis of ATP or GTP forming alpha-D-ribose 5-triphosphate and adenine or guanine, respectively.
Interaction partners:
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH
- Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL
- Putative phosphonates utilization ATP-binding protein PhnK
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG
- Probable transcriptional regulator PhnF
- Ribose 1,5-bisphosphate phosphokinase PhnN
- Phosphonates-binding periplasmic protein
- Phosphonates import ATP-binding protein PhnC
Sequence:
MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLAVDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTGMRLERRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLARQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRNHPFAGEIRSGYIDVSIVPEELGFAVNVGELLMTECEMVNGFIDPPGEPPHFTRGYGLVFGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHYVDFQAELELLKRLQQEQNHG
Protein: Baseplate wedge protein gp8 (Gene product 8) (gp8) (P19062)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Intermediate baseplate protein. Involved in the tail assembly.
Subcellular location: Virion {ECO:0000269|PubMed:2403438, ECO:0000269|PubMed:27193680}. Note=Present in 12 copies in the baseplate. {ECO:0000303|PubMed:21129200}.
Interaction partners:
Sequence:
MNDSSVIYRAIVTSKFRTEKMLNFYNSIGSGPDKNTIFITFGRSEPWSSNENEVGFAPPYPTDSVLGVTDMWTHMMGTVKVLPSMLDAVIPRRDWGDTRYPDPYTFRINDIVVCNSAPYNATESGAGWLVYRCLDVPDTGMCSIASLTDKDECLKLGGKWTPSARSMTPPEGRGDAEGTIEPGDGYVWEYLFEIPPDVSINRCTNEYIVVPWPEELKEDPTRWGYEDNLTWQQDDFGLIYRVKANTIRFKAYLDSVYFPEAALPGNKGFRQISIITNPLEAKAHPNDPNVKAEKDYYDPEDLMRHSGEMIYMENRPPIIMAMDQTEEINILFTF
Protein: Defective proboscis extension response 6, isoform A (LD13525p) (Q9VT76)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPIAHPLPLCVAWLLLLVVIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTAPTAAYTHPKWMEPYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSNADVASVRVHVLNGKYPLPCPTL
Protein: Protocadherin 7 isoform 4 (Q2TJI6)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
YCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTSNKYSKQPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVGEAEHMENDSRPLPDVALTGKCTRECDEYGHSDSCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEAAIMGDRNRNLLNKKLTSSYETFSAASFSKNEEANPEDIPLTKTGEYKPSPVNTLTRREVYL
Protein: Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (P50101)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Deubiquitinase involved in peroxisome import by mediating deubiquitination of the peroxisomal import receptor PEX5. Catalyzes deubiquitination of both monoubiquitiated and polyubiquitinated forms of PEX5 following its retrotranslocation into the cytosol, resetting PEX5 for a subsequent import cycle.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:21665945}. Peroxisome {ECO:0000269|PubMed:21665945}.
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 2
- Protein ECM30
- GMP synthase
- Ubiquitin carboxyl-terminal hydrolase 14
- Ubiquitin fusion degradation protein 4
- Polyubiquitin
- Ubiquitin-ribosomal protein eS31 fusion protein
- Peroxisomal ATPase PEX6
- Ubiquitin carboxyl-terminal hydrolase 4
- NEDD8-like protein RUB1
Sequence:
MSSEDELGSIGTVFPGSPIDKSIGSILPQFDEEVETLLEDSFTWNIPDWNELTNPKYNSPRFRIGDFEWDILLFPQGNHNKGVAVYLEPHPEEKLDETTGEMVPVDPDWYCCAQFAIGISRPGNGDTINLINKSHHRFNALDTDWGFANLIDLNNLKHPSKGRPLSFLNEGTLNITAYVRILKDPTGVLWHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLESDVPKHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKEFIHYEGFDYFAHDGFRLFAEELNDSGLQQINLKVLRTTKLSDIFASIKETMNIPQERDVKYWKMDYRRNSTLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKALLETVSFLDLFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKSNLLFVKSYDPHTQKLLGFGHFAVNQLQQLSDISAIIEDSISSNEKLTFYEEVQPGTINEIYMKETIYDADIDTGDIVSFEVPGAVLPDTFPVYATIKDFYSYLRYRVKLKFSKFDGSSEEYGVSNEIPESFEFWISAYAPYDDLARMVSKYAHVKPEYLKIIALYSNGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSVPLKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIGFTDEEKENILLWTNTNFQFQGLLSDQNTFKDVSKHSLLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATDRPMDDEQDLGMAIEHSEDMKGRIVVVQQYFKDLENRHGISFLFNLIPDETFPKTKDRLHAKFGLGQKEFSKIKLSIGYSTEEGTVFRSLQGFSDEELDKVILYDIMSNLDYIYMDHPDRLRSHSSYDRPMIIKN
Protein: Arogenate dehydratase 3 (PhADT3) (EC 4.2.1.91) (Prephenate dehydratase ADT3) (EC 4.2.1.51) (D3U717)
Organism: Petunia hybrida (Petunia)
Function: Converts the prephenate and L-arogenate produced from the shikimate-chorismate pathway into 3-phenylpyruvate and phenylalanine (Phe), respectively. Involved in floral volatile benzenoids and phenylpropanoids (FVBP) production (By similarity).
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:20215586}.
Interaction partners:
Sequence:
MQSLTPSSSGINIKLLNRKKIQTHRVTPSRVVIKCVYRFDSVNAGAAAVNTGVVNTPASNNTAGHVGASRTDWQSSCAILASKVVSQQQDTEKSGGAGNITAVNGHKILNLDLLPVESNRAKPLTITDLSPAPMHGAQLRVAYQGVPGAYSEAAAGKAYPKCEAIPCDQFEVAFQAVELWIADRAVLPIENSLGGSIHRNYDLLLRHRLHIVGEVQLPVHHCLLALPGVRKEYLTRVISHPQALAQCELTLTKLGLNVAREAVDDTAGAAEYIAANNLRDTAAIASSRAAELYGLDILEQGIQDDLSNVTRFVMLAREPIIPRTDRPFKTSIVFAHDKGTSVLFKVLSAFAFRNISLTKIESRPHRNRPIRLVDDANVGTAKHFEYMFYVDFEASMADVRAQNALAEVQEFTSFLRVLGSYPMDMTPWSPSRDA
Protein: F10A2.10 protein (Protease-associated (PA) domain-containing protein) (Putative peptidase) (Q9XH28)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDTLSQVSLVVYANYGRVEDFVRLKKDMGVNVSGAVVIARYGQIYKVDIVNNAYEAGAVGVVIYTNKRDYGGDEWFPASKWMPPSGFQVGTVYNGLGDPTTPGWASVDGCERLSDEAVELSGDVPLIPSLPVSAADAEVILKTIVGDVGPGPGILNLSYIVTKIQNVIGVIEGEEEPDRYVILRNHRDTWTFRAVDPNSGTAVLMEASKSYLQHIAQRLDKLQKRGWKPRRTIILCNWDAEEYGLVSSLSEISYWLFFFIIVYTNTSNISLKLHWKQNES
Protein: Uncharacterized GTP-binding protein C428.15 (O94362)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MGRDILIGFVGKPSSGKSTMLNALTDATAKTGNFPFTTIEPNRAIGYAQIECACSRFGLQDKCKPIYGGCKNGVRSIPIQLLDVAGLIPGAHAGKGLGNKFLDDLRHADALVHVVDVSGTTDAEGKVCRGYDPSVDIAWLYKEITAWIGNNLREKWPNIVRRHIATKANPVNTLQSQFSGYGSTPAVTAKVLDSLHLDTPLEKWDDDTIEKVVNRFVDIKFPTVIALNKIDHPDADANISKIARKEDPNRLVLASAISEVFLRRLAKQGFVKYEEGSEFVDTLDDFPDSGLKPLSENLKTRIADLQDMVLFRHGSTGVCNVLAKAMELLNLIPVFPVKNVHNFANSPNEGVFRDCILVKQGTTAGQVSQMVLGGEAMSIVGVNGNVGESDVIVPGKTDILHFRLRKAEA
Protein: Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Q9JJJ3)
Organism: Mus musculus (Mouse)
Function: Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines.
Subcellular location: Cell membrane {ECO:0000305|PubMed:23042941}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96PS8}. Basolateral cell membrane {ECO:0000305|PubMed:23042941}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96PS8}. Note=Functions at the hepatocyte basolateral membrane. {ECO:0000269|PubMed:23042941}.
Interaction partners:
- Aquaporin-11
- Aquaporin-12
- Aquaporin-8
- Aquaporin-1
- Lens fiber major intrinsic protein
- Aquaporin-4
- Aquaporin-5
Sequence:
MPSEKDRAKKNLVQRLALKSCLAKETLSEFLGTFIMIVLGCGSIAQAVLSREKAGGIITINIGFATAVVMALYATFGVSGGHINPAVSFAMCTFGRMEWFKFPFYVGAQLLGAFVGAATVFGIYYDGLMAFADGKLLITGENGTAFIFATYPKPFVSVPGAFVDQVVSTMFLLLIVFAIFDSRNLGVPRGLEPIVIGLLIIVISCSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFTFGNNFWWIPVVGPMIGAVLGGLIYVLFIQMHHSNPDPEVKAEPAENNLEKHELSVIM
Protein: Elongation factor P (EF-P) family protein (Putative elongation factor P (EF-P)) (Q8VZW6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Deoxyhypusine synthase
- Large ribosomal subunit protein bL28c
- Large ribosomal subunit protein bL31c
- Deoxyhypusine hydroxylase
- Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain-containing protein
- 50S ribosomal protein L33
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein bL21c
- Small ribosomal subunit protein uS9c
- Small ribosomal subunit protein uS10c
Sequence:
MAGRAIFSVSCSSTPSLCIPYSTASFSSMNRLALPAVRISPRTNRFPRIHCSMSANDIKAGTNIEVDGAPWRVLEFLHVKPGKGAAFVRTKIRNYVNGSTVERTFRAGISVEEANIYKETKQFTYKDGSQFVFMDLTTYEETRLNESDMGEKTKWLKEGMDCILLYWKDKVIDFDLPITVKLKVVDVDPGLRGDTVQGGSKPATMETGAIVAVPLFINVGEEIFVDTRTGAYMNRA
Protein: Insulin-like growth factor 2 (Insulin-like growth factor II) (IGF-II) (P33717)
Organism: Gallus gallus (Chicken)
Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for integrin which is required for IGF2 signaling.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P01344}.
Interaction partners:
- Fibronectin type-II domain-containing protein.
- Tyrosine-protein kinase receptor.
- Insulin-like growth factor-binding protein 2
- Uncharacterized protein.
- Uncharacterized protein.
- Tyrosine-protein kinase receptor
- Insulin-like growth factor-binding protein 5
- Transcriptional repressor CTCF
- IGFBP N-terminal domain-containing protein.
- Insulin degrading enzyme
Sequence:
MCAARQILLLLLAFLAYALDSAAAYGTAETLCGGELVDTLQFVCGDRGFYFSRPVGRNNRRINRGIVEECCFRSCDLALLETYCAKSVKSERDLSATSLAGLPALNKESFQKPSHAKYSKYNVWQKKSSQRLQREVPGILRARRYRWQAEGLQAAEEARAMHRPLISLPSQRPPAPRASPEATGPQE
Protein: Fc receptor-like protein 4 (FcR-like protein 4) (FcRL4) (Fc receptor homolog 4) (FcRH4) (IFGP family protein 2) (hIFGP2) (Immune receptor translocation-associated protein 1) (CD antigen CD307d) (Q96PJ5)
Organism: Homo sapiens (Human)
Function: May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}.
Interaction partners:
- Polymeric immunoglobulin receptor
- Tyrosine-protein phosphatase non-receptor type 11
- B-cell CLL/lymphoma 9 protein
- Complement receptor type 2
Sequence:
MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES
Protein: Exopolysaccharide phosphotransferase CpsY (EC 2.7.-.-) (Stealth protein CpsY) (P9WGD1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Malto-oligosyltrehalose trehalohydrolase
- 1,4-alpha-glucan branching enzyme GlgB
- cAMP/cGMP dual specificity phosphodiesterase Rv0805
- UDP-galactopyranose mutase
Sequence:
MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRKVLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTIDEPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVYEETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVVFDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYALRSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYNSHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKTRIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLIEMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVLYVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLERYFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA