wanglab/gogpt-training-data huggingface dataset:
Protein: Trailer hitch, isoform H (M9PF20)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- ATP-dependent RNA helicase me31b
- Protein cup
- Enhancer of mRNA-decapping protein 3
- LD37574p
- Decapping protein 1, isoform A
- Eukaryotic translation initiation factor 4E1
- 5'-3' exoribonuclease 1
- m7GpppN-mRNA hydrolase
- Polyadenylate-binding protein
- Fragile X messenger ribonucleoprotein 1 homolog
Sequence:
MSGGLPELGSKISLISKADIRYEGRLYTVDPQECTIALSSVRSFGTEDRDTQFQIAPQSQIYDYILFRGSDIKDIRVVNNHTLPHHNDPAIMQAQLQNGPPQMPQHFPMPSGMSGPPQQQQVPSQQPPQMPSGGGSGGAGGAGAPGGGGPGYGNGNPFGNLGGPNLANMVGNAGGSLAPGSGAPGSGPFMHIGGNQQQPKPQQQKQPISVLDMLAGASRSTTPISLIVSPTAELTQQQQLHQQQNAGQGGNGRDAGHKRQNHQQQQNQQHQQRGGPSHNNMQQQQQRGGGSGTDFYNQQRDRRDSGRQMDNNYSNNYNNNNNNQRNRGGGNGMQQQQRGGNGGSGGGGGNGGGNNPAWNMHRGNQNSNNMMNMRNRGMGSRGPMRPNQGYRPQSANNQNKPRNKIKFEGDFDFEQANNKFEELRSQLAKLKVAEDGAPKPATNATAATATATNEQVGEKVEGVHTLNGETDKKDDSGNETGAGEHEPEEDDVAVCYDKTKSFFDNISCEAAQDRSKNKKNDWRQERKLNTETFGVSSTRRGSSYRGRNQYYNNNGNGGINSGYGGAPGYNRNNYRMGGGGGNFRNRSNNRNNGGGRGGNGMPNITNGNTAAALKAANNAAGHGSNATDSSAPNATTATTKSTSLLPEQTQQVAAVSQ
Protein: Cyclin family protein (F4KD43)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAGVLAGECSYSESGVSSHSRNSHEKQEEVSRWYFGRKEIEENSPSRLDGIDLKKETYLRKSYCTFLQDLGMRLKLAWFLDIIAYVCTDVTIATAIIFCHRFFFRQSHAKNDRRTIATVCMFLAGKVEETPRPLKDVIFVSYEIINKKDPGASQKIKQKEVYEQQKELILNGEKIVLSTLGFDLNVYHPYKPLVEAIKKFKVAQNALAQVAWNFVNDGLRTSLCLQFKPHHIAAGAIFLAAKFLKVKLPSDGEKVWWQEFDVTPRQLEDVSNQMLELYEQNRVPASQGSEVESSVGGGSAQRPGSRNAVSTDEHVGSRQTSSVRSTHEQSNSDNHGGSSKGVLNQNNENGGGEAANVSVDNKEEIERETKESSLHLESHPAHKDNVREAPHNSRPLVEGPGKDNSEREGGELQDDGAVHKSRNVDVGDALISQSPKDLKLLRDKVKAKREKAKKLLGERTRKKDLMDEDDLIERELEDVQLAVEDEKTKERKVQSRPKAENSDLMGTEHGEILDVKGEVKNTEEGEMVNNNVSPMMHSRKRKMGSPPEKQSEGKRRHNSENGEESHKTSRGSSHHGDREHRRHSQENNHS
Protein: Uncharacterized protein, isoform D (A0A0B4KEH8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MIKNEQRPLNFEKCPESDDELKKRLEIEKLINKNIDKNISFDVLVKLSLAPYGLVNDDFRRILWPQLAGVDINHLGQAPTLDKFQCHPEYNQVVLDVNRSLKRFPPGIPYEQRIALQDQLTVLILRVIQKYPNLRYYQGYHDVAVTFLLVVGEEIAFAIMEQLSTTHFSECMQETMEATQRRLMFIWPIIKFENPELYQFLQNSTVGTLFSLPWYLTWFGHSLTSYRTVVRLYDYFLASPIYTSIFVTAAILLYRSDEILKEDCDMASIPEDLPFEDLLKTSSSLLNKYSLTLIEKDVEELICQERRKRKTDEALIVKRRQPATSNRIPIITKWLPNILTAKPVILTTAISIVVGVCAYYYNNQYLAAGIS
Protein: Hexokinase-1 (EC 2.7.1.1) (Protein GLUCOSE INSENSITIVE 2) (Q42525)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Together with sugar, is involved in the regulation of the expression of aquaporin genes, and reduces leaf water conductance, to coordinate sugar levels with the loss of water through transpiration. Regulates cell proliferation and expansion early during leaf development. Involved in sucrose-induced leaf growth stimulation independently of GPT2. May participate to the stimulation of hypocotyl elongation under long-day (LD) conditions. Forms a nuclear complex with CLF and EZA1/SWN to target common glucose-responsive genes and regulate glucose signaling. Is required for CLF- and EZA1/SWN-mediated histone H3 trimethylation on 'Lys-27' (H3K27me3) and glucose-mediated gene repression.
Subcellular location: Mitochondrion outer membrane; Single-pass membrane protein. Nucleus {ECO:0000269|PubMed:35394700}.
Interaction partners:
- Glucose-6-phosphate isomerase, cytosolic
- Glucose-6-phosphate isomerase 1, chloroplastic
- Probable phosphoglucomutase, cytoplasmic 1
- Probable phosphoglucomutase, cytoplasmic 2
- Phosphoglucomutase, chloroplastic
- Phosphomannomutase
- Fructose-1,6-bisphosphatase, cytosolic
- Fructose-1,6-bisphosphatase 1, chloroplastic
- Mannose-6-phosphate isomerase 2
- Mannose-6-phosphate isomerase 1
Sequence:
MGKVAVGATVVCTAAVCAVAVLVVRRRMQSSGKWGRVLAILKAFEEDCATPISKLRQVADAMTVEMHAGLASDGGSKLKMLISYVDNLPSGDEKGLFYALDLGGTNFRVMRVLLGGKQERVVKQEFEEVSIPPHLMTGGSDELFNFIAEALAKFVATECEDFHLPEGRQRELGFTFSFPVKQTSLSSGSLIKWTKGFSIEEAVGQDVVGALNKALERVGLDMRIAALVNDTVGTLAGGRYYNPDVVAAVILGTGTNAAYVERATAIPKWHGLLPKSGEMVINMEWGNFRSSHLPLTEFDHTLDFESLNPGEQILEKIISGMYLGEILRRVLLKMAEDAAFFGDTVPSKLRIPFIIRTPHMSAMHNDTSPDLKIVGSKIKDILEVPTTSLKMRKVVISLCNIIATRGARLSAAGIYGILKKLGRDTTKDEEVQKSVIAMDGGLFEHYTQFSECMESSLKELLGDEASGSVEVTHSNDGSGIGAALLAASHSLYLEDS
Protein: Aquaporin PIP2-5 (Plasma membrane intrinsic protein 2-5) (ZmPIP2-5) (ZmPIP2;5) (ZmPIP2a) (Q9XF58)
Organism: Zea mays (Maize)
Function: Water channel required to facilitate the transport of water across cell membrane. Its function is impaired by Hg(2+). May play a role in water uptake from the root surface. Active as homomers. Increased activity when heteromerization with PIP1-2.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14671024}; Multi-pass membrane protein {ECO:0000269|PubMed:14671024}.
Interaction partners:
- VAP27-2
Sequence:
MAKDIEAAAAHEGKDYSDPPPAPLVDAEELTKWSLYRAVIAEFVATLLFLYITVATVIGYKHQTDAAASGPDAACGGVGVLGIAWAFGGMIFILVYCTAGVSGGHINPAVTFGLFLARKVSLVRALLYIVAQCLGAICGVGLVKGFQSAFYVRYGGGANELSAGYSKGTGLAAEIIGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSLGAAVIYNNDKAWDDHWIFWVGPFIGAAIAAAYHQYVLRASAAKLGSSASFSR
Protein: Candida glabrata strain CBS138 chromosome J complete sequence (Q6FP75)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
Sequence:
MKFQVALTSLLAAAAVASPVEDLFKHKAKKSSTSSVHPSSTTKGKPTSSAHAKALPSSLASLLANTTGNASNMTNSTVAPQKQQLQVIYTGGQVAIPSTNATNTTAFSTNSTALFNTTSALNITELYSVAATINQTLADNSTKGAVVVANAKSLESLGFLTSIVLDSKKPIVISADEKMALAVANETAAWNRGPLVVSKEGLVYAGIFTPSSANAVGLPVAVIDDAKKVQWFFSPAPPALINSNSTIRVNYTNFTNTDIEFAATPLVPIVYDGGYSSSLISSLASTVQGLVVVSSGSSNSTTSTIESAQIPVVYANSGAPLTPVSSKDVPQNALSAGYLTPVKAQLLLSIAAINGVNSDEALMSIFPN
Protein: Protein METABOLIC NETWORK MODULATOR 1 (Q8L7T9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Lineage-specific modulator of primary metabolism. Influences flowering time.
Interaction partners:
- Polyadenylate-binding protein interacting protein
- Cytochrome b561, DM13 and DOMON domain-containing protein At5g54830
- AT5g54940/MBG8_21
- DNA-binding bromodomain-containing protein
- Tubulin beta-2 chain
Sequence:
MEKESHEENNHTISGDLTAKRKRGRPRKQLKLESNEHSLGHSPSFSRSQQQSRQRNDDEAMVGQPISGVIEATFEAGFLLSVKVGNSDSMLRGVVFKPGHCDPVSVDNDVAPDVPMIRRNSDVMHHDGSAKRGRKSRFREKRGSGVRSRALVPVPIQPAHPTIPNNLIVPVVLQPAHLENGGERVPIDHSPMQTETGSQASGASNGKPFETLLTQVMNKGQVQHTTQSVEPESDEQALSIEPLQAIHPIHPVHMLKPMPSYGRGKMTELLQAVQENVRETHFSQGH
Protein: Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) (O44437)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P62318}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62318}.
Interaction partners:
- U1 small nuclear ribonucleoprotein C
- Probable small nuclear ribonucleoprotein Sm D1
- Probable small nuclear ribonucleoprotein G
- Probable small nuclear ribonucleoprotein Sm D2
- Probable small nuclear ribonucleoprotein E
- U6 snRNA-associated Sm-like protein LSm7
- Small nuclear ribonucleoprotein-associated protein B
- Small nuclear ribonucleoprotein F
- Lsm10
- Probable U2 small nuclear ribonucleoprotein A'
Sequence:
MSIGVPIKVLHEAEGHIITCETITGEVYRGKLIEAEDNMNCQMTQITVTYRDGRTANLENVYIRGSKIRFLILPDMLKNAPMFKKQTGKGLGGTAGRGKAAILRAQARGRGRGGPPGGGRGTGGPPGAPGGSGGRGAWQGGPTGGRGRGGL
Protein: Transcription factor MYB35 (Myb-related protein 35) (AtMYB35) (Protein DEFECTIVE IN TAPETAL DEVELOPMENT AND FUNCTION 1) (Q9LSI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for anther development and early tapetal function during microspore maturation. Regulates callose dissolution required for microspores release from the tetrads.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:18397379}.
Interaction partners:
- Transcription factor DYT1
- Short-chain dehydrogenase reductase ATA1
- Protein SPOROCYTELESS
- Cytochrome P450 703A2
- Leucine-rich repeat receptor protein kinase EMS1
- Transcription factor bHLH91
- ABC transporter G family member 26
- Transcription factor bHLH89
- Cytochrome P450 704B1
- Type III polyketide synthase B
Sequence:
MGRPPCCDKSNVKKGLWTEEEDAKILAYVAIHGVGNWSLIPKKAGLNRCGKSCRLRWTNYLRPDLKHDSFSTQEEELIIECHRAIGSRWSSIARKLPGRTDNDVKNHWNTKLKKKLMKMGIDPVTHKPVSQLLAEFRNISGHGNASFKTEPSNNSILTQSNSAWEMMRNTTTNHESYYTNSPMMFTNSSEYQTTPFHFYSHPNHLLNGTTSSCSSSSSSTSITQPNQVPQTPVTNFYWSDFLLSDPVPQVVGSSATSDLTFTQNEHHFNIEAEYISQNIDSKASGTCHSASSFVDEILDKDQEMLSQFPQLLNDFDY
Protein: Rho-related protein racH (Q9GPR7)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Rac guanine nucleotide exchange factor B
- Uncharacterized protein
- Ras guanine nucleotide exchange factor S
- GTPase activating protein homolog 1
- Putative rho GDP-dissociation inhibitor 1
- Cofilin-1A
Sequence:
MVKDIKVMVVGDMSVGKTCLLISYTTNSFPGEYVPTVFDNYNANAIVNNTPINLGLWDTAGSEEYNSFRPLSYPGTDVFIICFSLISQTSFENVIKKWHPEIIQNMEQVPPIILVGTKLDLRGKGKSEEKEVTPEMGEQMRAAIGAYKYSECSALTQDGLTTVFEEAGRVVLFPPSKEELAKSKKDSKKGDKDSKDCIIQ
Protein: Heat shock protein 83 (BmHSP90) (Q9BLC5)
Organism: Bombyx mori (Silk moth)
Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Required for piRNA biogenesis by facilitating loading of piRNAs into PIWI proteins.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Uncharacterized protein.
- TPR_REGION domain-containing protein.
- PAS domain-containing protein.
- PPIase FKBP-type domain-containing protein.
- Aha1_N domain-containing protein.
- CS domain-containing protein.
- p23-like protein
- Endoplasmic reticulum chaperone BIP
- Uncharacterized protein.
- Uncharacterized protein.
Sequence:
MPEEMETQPAEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELYIKIIPNKNEGTLTIIDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADRVTVHSKHNDDEQYVWESSAGGSFTVRPDSGEPLGRGTKIVLHVKEDLAEFMEEHKIKEIVKKHSQFIGYPIKLMVEKEREKELSDDEAEEEKKEEEDEKPKIEDVGEDEDEDKKDTKKKKKTIKEKYTEDEELNKTKPIWTRNADDITQDEYGDFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKRKNNIKLYVRRVFIMDNCEDLIPEYLNFIRGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEELAEDKENYKKYYEQFSKNLKLGIHEDSQNRAKLSELLRYHTSASGDEACSLKEYVSRMKENQKHIYYITGENRDQVANSSFVERVKKRGYEVVYMTEPIDEYVVQQMREYDGKTLVSVTKEGLELPEDEEEKKKREEDKVKFEGLCKVMKNILDNKVEKVVVSNRLVESPCCIVTAQYGWSANMERIMKAQALRDTSTMGYMAAKKHLEINPDHSIVETLRQKAEADKNDKAVKDLVILLYETALLSSGFTLDEPQVHASRIYRMIKLGLGIDEDEPIQVEEPASGDVPPLEGDADDASRMEEVD
Protein: Pruning defect 1, isoform B (A0A0B4KH60)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MESPLLPKANNNLGMDKMSSSLNSSTMEDTTPSDSGVQLLDSENSDVMVESICSYEENVRPMPLPLVDPNSNVTAAPDESMTISECSTFDTTEKIVYRRKVHKASSASKTPKKRVSFHEDILKNTRTDNIHIEHGFITYKNGRKLAFANSAGVAGAPGRYSWCPDRERPEGPNELSAAGREDDGEEATGGGGARRKRHLVYRNACSDVLDYDNIFDTDEAPGLHYDTSGVFEYGPATQKQEEQPQLYKCVCSSSNSSLDSDEQDKNSNANCKQYEQAKSSSCDCIGMSNANNNLIGDNCYYSEPNIGDADSPKVKSVWNKEKKPKSSCLKKTKLHTNVILEQDLNGRVKKFNVHDIKHQLLDNSSKMIFGSLKSIFTMPLPERGVPEGSEDLQAVVECVPELEQTPEHKSRPAAESPPLRAKPFLSKSLDGSKQAQPVKKFVHNVDEQLRHKNEDDGASSTEASPMESKQSLMLHRQEEFDKETVPMGSAQGEFRSKFIINCESTVFEHTGVSYETGDLQSELSSGIQHTSVASLLEQNTPIAEPAASQIKKSFLDAPIAKTFSNFFRSFKDSTPVAKDEQAVTDNYFASKIAKPQQQAPAAGKLQRNFSSSTISEPSSNTNTSSNHQIAMNPQLGNAERQSRHLPSPLKKRGQPLQPPRYYDQQHPHQSRSLHSPSAYLAAGRGGPGDTTNARSMDSDLVIVDYTDVDYAHLLKPPAPAAKTSLINRFLRNVTQKKIMETSIRKNNFFADKLRTEQRHAGSDLYVKGARPKNYELIDDLNAEIAMEIEMCGTNSPRRELAISLDNDFQGNLSNFELGIGEISIDVFKGKSLFNLKQSNEQLMKAFKLYTGYNVDGIMTPVLVLLTDKTLYVVNMEGNSLCVKFVLAYKDLDVILMGPFGNTVLLSNSNRDMQQVLLAGGPYPAGSLVANLELCARRSGSTLPAVGQLTLEHLAPLQAFVRANSCVGVAEHWMLYAVVNVPAGGSMRVESPSELLGPSMKGFLMHRRLRQTISTSAANRIFWQPGYFLLKAGVLYMFNDSTQRLPSWAMALAECQGARRTVKSERPHCFEITLKGEVLQMAAPDEYVASEWLQALLQSASGLVVQEEKHKTLGCTLIVTDNHLITLREDFSAPLRKISQQADNNAAVQGNKETMLEEDMLSVFETSSLMGSTISTPTRGTQHSYSSLSSTPTKQTNEDAAPKETVASPEKSQRMTSVYGKNSGLAILTCADIKEMTGIKITSRSETWWCILEFSCQEAPLENQDDLVIFFASSMEMQRFLRLLEQLWQSKNNDLFPITILDDGDSLAEQYNKLYMDTNRAWEPLLSAALG
Protein: Gap junction alpha-3 protein (Connexin-44) (Cx44) (Q9TU17)
Organism: Ovis aries (Sheep)
Function: Structural component of lens fiber gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
Subcellular location: Cell membrane {ECO:0000269|PubMed:30542154}; Multi-pass membrane protein {ECO:0000269|PubMed:30542154}. Cell junction, gap junction {ECO:0000269|PubMed:30542154}.
Interaction partners:
Sequence:
MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEEVWGDEQSDFTCNTQQPGCENVCYDRAFPISHVRFWVLQIIFVSTPTLIYLGHVLHLVRMEEKRKEREEEPPKAAGPAEEHQDPAPVRDDRGKVRIAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFQLKPLYRCDRWPCPNTVDCFISRPTEKTIFILFMLAVACVSLLLNVLEIYHLGWKKLKQGMTSPFRPDTPGSRAGSAKPMGGSPLLLPPNSAPPAVTIGFPPYYAPSASSLGQASAPGYPEPPLPAALPGTPGTPGTPGTLGGGGGNQGLRAPAQNCANREAEPQTSARKASPPASTPPAAPAGGPQQFLPGGAAGSSGDSDGEGAVTAVELHAPPEPPADPGRSSKASKSSGGRARAADLAI
Protein: GH11587p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform C) (Q9VRB7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cytosol aminopeptidase
- GH18016p
- Cytosol aminopeptidase
- FI09604p
- GH14622p
- Hydra, isoform A
- IP07141p
- Uncharacterized protein, isoform A
- GH06435p
- GH07855p
Sequence:
MQRSIFKSSCSRTLILLNSLKSMHHKSLHVEQLLEAAPAPKNRCLDLLGRLIHGRLSLLGGRPVPPRFLPLLAGDRSLYFNADEDEEFRKRLAMQLKELRETLQEKQELREGQEQDFQELEQQDEEEDQPYVPRSREISMEDLTDEELSDVRGLRMSASQDDGKSGNFEQPETSELESEETADAKDPRESGQPREPQDAHDAIEHVREGEIEGVYWTGEGKRIVTQTPQRKTGHSGFIDGHGEEIPQEDSKQEVAPYHPEPRAQAQATSKVIRKGRKPKSSTKTNTPSDSDE
Protein: Protein REPRESSOR OF SILENCING 3 (Q9FGT1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: RNA-binding protein required for DNA demethylation and to eluviate siRNA-mediated transcriptional gene silencing (TGS), probably by guiding ROS1. Can bind specifically single stranded G-rich RNAs of 21-, 24- or 26-nt corresponding to promoter sequence of target genes; this interaction directs demethylation of target sequences.
Subcellular location: Nucleus {ECO:0000269|PubMed:18815596}. Nucleus, nucleolus {ECO:0000269|PubMed:18815596}. Nucleus, nucleoplasm {ECO:0000269|PubMed:18815596}. Note=Localized in discrete foci dispersed throughout the nucleus. {ECO:0000269|PubMed:18815596}.
Interaction partners:
- DNA glycosylase/AP lyase ROS1
- Increased DNA methylation 1
- Increased DNA methylation 3
- Increased DNA methylation 2
- DEMETER-like protein 2
- DEMETER-like protein 3
- Methyl-CpG-binding domain-containing protein 7
- Transcriptional activator DEMETER
- Polynucleotide 3'-phosphatase ZDP
- DNA-directed RNA polymerase IV subunit 1
Sequence:
MEEKSSGGGVRLHVGGLGESVGRDDLLKIFSPMGTVDAVEFVRTKGRSFAYIDFSPSSTNSLTKLFSTYNGCVWKGGRLRLEKAKEHYLARLKREWEAASSTSDNTIKAPSDSPPATHLNIFFPRLRKVKPMPLSGTGKHKYSFQRVPVSSSLPRSFCDCEEHSNSSLTPREIHLHDLEAVNVGRQEAEVNVMNSVMNKLFEKNNVDPEEDNEIEADQDNLIINVASSGNDMDSALDMLSRKRKSILNKKTPSEEGYSEGRKGNLTHPSKNRQTISLEETGRQESSQAIRGKKKPSEVVPDKSSDEPSRTKDLEQSIDNISWSQKSSWKSLMANGNSNDFSVSSFLPGVGSSKAVQPAPRNTDLAGLPSRENLKKKTKRKRVTSTIMAEDLPVSDDIKRDDSDTMADDIERDDSDAVEYYTACESMADDTASDSVAERDDSDAVEDDTAIDSMADDPASDSVAESDDGDAVENDTAIDSMADDTVSNSMAESDDGDNVEDDTAIDSMCDDTANDDVGSDDSGSLADTVSDTSVEAVPLEFVANTEGDSVDGKSNVEKHENVAEDLNAEKESLVVKENVVDEEEAGKGPLKASNKSTGGSSWLQKASWTQLVSDKNTSSFSITQLFPDLTSDKGEAAGVINNVGNQFSNSNQTASAMKQTDYASSSGGFVAAGVPVDSTPVRSLDENRQRLNGKNVSEGAKLGAKKKIIKRKVGSGDTCTFMRSSTSLKEWAKAKKALSEPRRKKNSEE
Protein: Endoglin (A0A8I6GL08)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTKTFGSQSKLGLAERVGCDLQRVDSTRGEVTYTTSQVSEGCVAQVANAAHEVHVLFLNLSRRKSEVELTLQASKQNGTETREVFLVFISNENVLVKLQAPEIPLHLVYNSSLEVFKGPKVNSTPLPSFTSKTQILDWAATKGTITSIAALDDPKSIVLRLGQDPKAPPFCFPEAQKDMGVTLEWQPRTQTPVQGCHLEGVTGHKEAYVLRIRSGSEAGPRTVTVTVKLSCTSGDAVLILQGPPYVSWLIDTNHNMQIWTTGEYSIKIFPENNIKGFELPDTPQGLIGEARKLNASIVTFVEIPLTSDVSLTVSSCGGGLQTSPAPVVTTPPKDTCSPELLMSLIQPKCGNDVMTLALNKKLVQTLQCTITGLAFWDSSCQAKDQDGHLVLSSTYSSCGMKVTDHVISNEVIINLPSGLPPLRKKVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQGFVQVSMSPLTSEVTVQLDSCHLDLGPEGDMVELIQSRAAKGSCVSLLSPSPEGDPRFSFLLRVYMVPTPAAGTLSCNLALHPSTLSQEVYKTVSMRLNIVSPDLSGKGLVLPSVLGITFGAFLIGALLTAALWYIYSHTRAPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
Protein: TRAF3-interacting protein 1 (Interleukin-13 receptor alpha 1-binding protein 1) (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3) (Q8TDR0)
Organism: Homo sapiens (Human)
Function: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12935900}. Cell projection, cilium {ECO:0000269|PubMed:26487268}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q149C2}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q149C2}. Note=Microtubules (PubMed:12935900). In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268). {ECO:0000269|PubMed:12935900, ECO:0000269|PubMed:26487268}.
Interaction partners:
- Intraflagellar transport protein 20 homolog
- Intraflagellar transport protein 80 homolog
- Clusterin-associated protein 1
- Intraflagellar transport protein 57 homolog
- Intraflagellar transport protein 172 homolog
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 27 homolog
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport protein 22 homolog
- Intraflagellar transport protein 70B
Sequence:
MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKSDNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICAVKANILKNEEKIQKMVYSINLTSRR
Protein: Mlx interactor gamma (Q9BKE4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPDDWTTDTLFSAINVPFPFPDSREIARGAGIADFIQPSLGPLQPNLDDIDISFSDLIPTTRLPPVPEEGTDAEMLKNDEYCLSAIVGAPHTLYCNDSIMDVVNSSNNGAVNVDASMLELNTPINNVSYGEVEQRFSVARQVQQSNNDSQLLGDSGSMSGRIHGGKHFGPASANDNNTNRCVINGRVAKSTQRPFRREPHNYDKAQPTMHQTNLYQQMLAEQQKNQQQQHVVVSSFQASQQQQLAQQQPFSAQATNAFNNQSFISSYADNYQHQQQLNVKVEPLHADVLSLLNDNAYNSIGYKPYPQFKKSASTGTFLNVPRQTQQQQSYLQQEPPQMQQSLPVGMGNQQILQLTRQQQVNNTQQQQHQSTVASLLQQQHQQQNHQQQQLQTAVSSATWVSPNTILPKEIYRSNSLPLNVSLNKLPDGRQLHHEQPFAVPKYHSKSKSRVRSNSMHQQHTSVVSAAGAGSSSLGAHSCSNLLVTQQMQQATSDPMLNSTLAQLLTSNSRLQTAVANSSSSNSPSVSAIATTNSNSNAPPVHYANVTSPLSVPVPTHQHSPKKSASLPMAVNSALHSPPLGSKIHGIGLATANVGSNSLSLSPESTFHESQDSPLSPTTSLKFQPRDTQRRAGHIHAEQKRRYNIKNGFDTLHALIPQLQLNPNAKLSKAAMLQKGADHIKQLRQERNVLKDKIEALRMERDELNNSLTHLHSILPANGAPVTRQGTEHVRQLYDIYVRYNTMNDWKFWILGLILEPLLASYTSTVSSASLDELRRTAFLWVDQHCSLIDLRPAVTNKLKYLSMHTDIVSEPPSTLQEEVAKALQNSSGQHPNLHGP
Protein: Solute carrier family 43 member 3 isoform X1 (Solute carrier family 43 member 3a) (E7F4C3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Rho/rac guanine nucleotide exchange factor
- Phospholipid scramblase
- Si:dkey-165a24.9
- Si:dkey-26i13.8
- Beta-galactosidase
Sequence:
MMAYKGSSGKVVRYKLTLATGLLECLCFAGVVFGWASLVFVLKTDGYFGDLCSNATDAGGEFSSDCGLQDEHFSLVFTVASFMNNFLTLPNGFLYDHFGTMATRLLAIFLYTTGTLIVAFSNKALSVLLFPALSFIAVGGILFLMTNMQVGNLFGSHRSTIITVYNGAFDSSSVIFLIIKVLYEKGVSLRSSFLFLSACNLIHLIRTLFLMPKSHIPYPIPQDYQYGISCAKSNSYNVEEYEAKREASSDRSRRAEEELLETDSIKLTDNPEKDSFRSCVLSWFFLWHLVWLSVMQLRHYFFIGTLNPMLNRLANQNPVTVSEYTNAFAFTQFCGVLCAPWNGLLMDRHKRKPLDPDVSEREADLRSSILSLLLTSLQCFLFSICASIPFLPLQYLTFILQVLNRSFLYGGNAAFISIAFPARHFGKLYGLVMSLSAVVSLLQYPCFALNKALGGDPLYVNILLTILTLLAFIHPVYVFLHCRELAKHRENSRTLEASIQETSMY
Protein: CENP-B homolog protein 2 (CBHP-2) (O60108)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Binds to the central core and core-associated repeat regions of centromeric heterochromatin.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00583, ECO:0000269|PubMed:11238404}. Chromosome, centromere {ECO:0000269|PubMed:11238404}.
Interaction partners:
- ARS-binding protein 1
Sequence:
MPPLRRQALTLAEKKAIRKHYFESATKPSQQELISWFEEHFHKKLAQSTVSSILSSKNEFLDNLDAENSQIRRNRQGKYPILENALIDWQTRLQKQDGAITGNAIKKSAAELWRRIPEYSELPIPEFSNGWLEKFKKRCLKHGLKLQGESTSVNQGTYEENMVQIQELISLFDPKDIFNMDETGLCWKLIPNQSPASERVKGITRDKARVTVTICCNATGSEKAPLWVIGYAKSPRAFRQANAHPDSMDFHWRYNGTARMTTSIMEEWLRWFDDLMKGRKVLLILDKFVAHECALENIRNSERKLVNTTVVFLPVNSTEIYHPCGQEIVYAFKSYYRKYWLNYMLEEIRLGKNPSKTMNVLKAVRWMIRSWNVDFEPSIIYNCFLRSGLFQNQQPLTGPSPETIRIAVNLQELIGKYLGDKDIFQIENFINPIEENSADTNDDIVNQVAAQFLDEREFETDEEEEESQYLLSTKDAINAINTLLNFQEQSEDGNVLFTRTLLQFQKVLESRSIV
Protein: M protein (Q6V4L9)
Organism: Streptococcus pyogenes
Subcellular location: Secreted, cell wall {ECO:0000256|PROSITE-ProRule:PRU01372}; Peptidoglycan-anchor {ECO:0000256|PROSITE-ProRule:PRU01372}.
Interaction partners:
Sequence:
RKLKTGTASVAVALTVLGAGFANQTEVKAADHPSYTAAKDEVLSKFSVPGHVWAHEREKNDKLSSENEGLKAGLQEKEQELKNLKADVEKLKDAAELERLKNERHDHDELERLKNERHDHDKREAERKALEDKLADKQEHLDGALRYINEKEAERKEKEAEQKKLKEEKQISDASRQGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKDLADLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAEKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETT
Protein: RNA-editing ligase 2, mitochondrial (RNA ligase 2) (EC 6.5.1.3) (TbMP48) (P86925)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: RNA editing in kinetoplastid mitochondria inserts and deletes uridylates at multiple sites in pre-mRNAs as directed by guide RNAs.
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- RNA-editing ligase 1, mitochondrial
- MP18 RNA editing complex protein
- RNA editing complex protein MP63
- RNA editing associated helicase 2
- REH2-associated factor 1
- Metallo-beta-lactamase domain-containing protein
- RNA editing complex protein
- RNA editing complex protein MP67
- REH2-associated factor 2
- RNA editing complex protein MP46
Sequence:
MLRRLGVRHFRRTPLLFVGGDGSIFERYTEIDNSNERRINALKGCGMFEDEWIATEKVHGANFGIYSIEGEKMIRYAKRSGIMPPNEHFFGYHILIPELQRYITSIREMLCEKQKKKLHVVLINGELFGGKYDHPSVPKTRKTVMVAGKPRTISAVQTDSFPQYSPDLHFYAFDIKYKETEDGDYTTLVYDEAIELFQRVPGLLYARAVIRGPMSKVAAFDVERFVTTIPPLVGMGNYPLTGNWAEGLVVKHSRLGMAGFDPKGPTVLKFKCTAFQEISTDRAQGPRVDEMRNVRRDSINRAGVQLPDLESIVQDPIQLEASKLLLNHVCENRLKNVLSKIGTEPFEKEEMTPDQLATLLAKDVLKDFLKDTEPSIVNIPVLIRKDLTRYVIFESRRLVCSQWKDILKRQSPDFSE