wanglab/gogpt-training-data huggingface dataset:
Protein: 3-phosphoinositide-dependent protein kinase B (EC 2.7.11.1) (Pdk-class protein kinase b) (Q54PK9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Probable serine/threonine-protein kinase DDB_G0288795
Sequence:
MINGRYQKEDVVNNNNNLNLNLIEKTLNDLTIKNNTNINNNNTNNKNTNYYNNNNFNNNNNNNNNNNNNNNNINNNNNNNKYLNNSHNNNNNNNNNNNNNNNNNNNNNNNEINNNNNNVLSHSSLSGKGGSTTYETTSYTTSITSSRDTGTISTSYESSSSSSSSSSSSLYDDDEYSDYSDSSDSIDSYVNHRQALSKSQQQQHLQQQQDQPQPLHSSMGAISNEKPPSPTNQQQQQQHHHPKHNIELPKTSSFGLQPNSSIPHKKSRSDFDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYVNTEKTILDSLDNPNIVKLFYTFQDENNLYFILEYCPNGDLLGALKKAGCFSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQHLKLSDFGSAKQLSIGSHHKGSRSGSFCGTAEYVCPELLTEKSAGVEADIWSYGCLLYQLVSGKLPFKGFNEYQTFLLITKREFSYPDNFDKCCMNLIDQLLDLDPYKRPTISEIKNHEFFSSIQDWSSIPSQTPPPIEQMVPQSPFPSPNSSLRLKKRSLSVGSPINSSLTYLSQPPIKPLNLDNSNIDYNDFENNQIISNNNNNNNNTTTTTTTTTTSANTSGSTNNTLYFTSPNVTSPPTSMSSNNTPRYINPLPTQSTTTTTTKPAYSSTPSSTILKSTPPPPILSSCSSNNLLGKSSNQQYQPFQFHQQQQQQQQQQQRERSSTTTPSPTFLSNHHNQHQKNLQQSFSSIDKSSFSTSSPMSSPRILLKPTELVLMDKDRKRNIREQQQIDQYQWSRFLLPNDEIILACGITEKRSGLITKKRQLIITDTPRIFYVDPVKMTQKGEITVDGSLSAQQKSSKHFIINSKGRSRHFYDLDGQSKLWVDLINELNMLSFK
Protein: Glucagon a (F1RD10)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Somatostatin
- Insulin
- Glucagon receptor a
- Glucagon receptor b
- Appetite-regulating hormone isoform X1
- Insulin
Sequence:
MKGVQYFASLLLLLFVHKCICVPLQGDSTSTETADSFLARAPGLTTMKRHSEGTFSNDYSKYLETRRAQDFVQWLMNAKRNGGSVKRHAEGTYTSDVSSYLQDQAAQSFVAWLKSGQPKPE
Protein: YEATS domain containing 4 (F8W0J4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00376}.
Interaction partners:
Sequence:
MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEVTLYHLLKLFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI
Protein: Activating transcription factor 7 interacting protein (F5H2W9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPEGSKAEWKETPCILSVNVKNKQDDDLNCEPLSPHNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASG
Protein: Ionotropic receptor 21a (Q9VPI2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Integral part of a neural sensory system in the antenna that provides the neural basis for the response to environmental changes in temperature (thermosensation). Together with Ir25a and Ir93a, mediates the response of the dorsal organ cool cells, a trio of cool-responsive neurons, to cooling and is required for cool avoidance behavior.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Ionotropic receptor 40a
- Ionotropic receptor 41a
- Ionotropic receptor 75d
- Ionotropic receptor 8a
- Ionotropic receptor 64a
- Ionotropic receptor 60a
- Ionotropic receptor 31a, isoform C
- Ionotropic receptor 87a
- Ionotropic receptor 92a
- Ionotropic receptor 84a
Sequence:
MSYYWVALVLFTAQAFSIEGDRSASYQEKCISRRLINHYQLNKEIFGVGMCDGNNENEFRQKRRIVPTFQGNPRPRGELLASKFHVNSYNFEQTNSLVGLVNKIAQEYLNKCPPVIYYDSFVEKSDGLILENLFKTIPITFYHGEINADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKILGPQTESRVVLVSRSTQWRLRDFLSSELSSNIVNLLVIGESLMADPMRERPYVLYTHKLYADGLGSNTPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGVEFRLLTMISKRLNFSIDITETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYITQERLMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVALICVYLGGIFPIVFTDRLTLSHLMGNWGEVENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLLGLFFRVGTLNNGGWETWFQNSTHIPTSRLYKKMEFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQIIKRSRKSAASSWSSASSGSMLRTNAEQLSHDKRKANRREAAEVAQKMSFGMRELNLTRATLREIYGSYGAPETDHGQLDIVHTEFPNSSAKLNNIEDEESREALESLQRLDEFMDQMDNDGNPSSHTFRIDN
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q7K2V5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGNDDHRRRKTPCGFCMAVFKWIPVLFITAVIAWSYYAYVVELCIRNSENRIGMIFMLLFYHLFLTLFMWSYWRTIMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSVRFCEKCKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVEFWKVGAGQLNASGMGRFHILFLFFIAIMFAISLVSLFGYHIYLVLVNRTTLESFRAPIFRVGGPDKNGYNLGRYANFCEVFGDDWQYWFLPVFSSFGDGKTFPIRHMEEDTESLLGYHSDTRIELEEDFLPEPRFQDSIP
Protein: Mas-related G-protein coupled receptor member D (Beta-alanine receptor) (G-protein coupled receptor TGR7) (Q7TN41)
Organism: Rattus norvegicus (Rat)
Function: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Transient receptor potential cation channel subfamily V member 1
- Transient receptor potential cation channel subfamily A member 1
Sequence:
MNYTPYSSPAPGLTISPTMDPVTWVYFSVTFLAMATCVCGIVGNSMVIWLLSFHRVQRSPFCTYVLNLAVADLLFLLCMASLLSLETGPLLTASTSARVYEGMKRIKYFAYTAGLSLLTAISTQRCLSVLFPIWYKCHRPQHLSGVVCGVLWALALLMNFLASFFCVQFWHPDKYQCFKVDMVFNSLILGIFMPVMVLTSAIIFIRMRKNSLLQRRQPRRLYVVILTSVLVFLTCSLPLGINWFLLYWVELPQAVRLLYVCSSRFSSSLSSSANPVIYFLVGSQKSHRLQESLGAVLGRALQDEPEGRETPSTCTNDGV
Protein: Cleavage stimulation factor, 3' pre-RNA, subunit 3 (A0JPN7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSGDAAAEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDARTRHHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFREEYEGKETALLVDRYKFMDLYPCSASELKALGYKVCTQQQDGRSVPLPLRFQESMHCTVFILRSILYSVATKTKIFH
Protein: Calcium uniporter protein 4, mitochondrial (AtMCU4) (Q1PE15)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:28031475}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Calcium uptake protein, mitochondrial
- Mechanosensitive ion channel-like protein
- Probable glutathione S-transferase DHAR4
Sequence:
MVMMKKLLSNRLFNMSKTASQSLMNCRTSSSSSLAMRTRVPKDIGEATIDPEPGDLTISQRFLNKFSMNGIDTTSKMSIGESLMEKLKEMDMNKDRIRLDGLSHPKEETLGLTVQDVKKLLRAAEIEVIKTKLMETGKIWIRYSDFLGVCSDSSLDPSQGALIAKMLDDSGNVIVMGNSVCLRPHQLTKSIEGLLPLSQIHNPNDPRRKELNELEAIKTVIDQKAHSLVRRELWAGLGYLIIQTAGFMRLTFWDLTWDVMEPICFYVSSVYFMAGYTFFLKTSREPSFQGFYQSRFEAKQRKLMQSEDFDVGRYDELKKLFNPKPSGAVPKILGSLQN
Protein: Transmembrane protein 61 (Q8N0U2)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MALPQMCDGSHLASTLRYCMTVSGTVVLVAGTLCFAWWSEGDATAQPGQLAPPTEYPVPEGPSPLLRSVSFVCCGAGGLLLLIGLLWSVKASIPGPPRWDPYHLSRDLYYLTVESSEKESCRTPKVVDIPTYEEAVSFPVAEGPPTPPAYPTEEALEPSGSRDALLSTQPAWPPPSYESISLALDAVSAETTPSATRSCSGLVQTARGGS
Protein: Bifunctional fucokinase/GDP-fucose pyrophosphorylase (AtFKGP) [Includes: Fucose-1-phosphate guanylyltransferase (EC 2.7.7.30) (GDP-fucose pyrophosphorylase); L-fucokinase (EC 2.7.1.52)] (Q9LNJ9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L-fucose 1-phosphate and GTP.
Interaction partners:
- GDP-mannose 4,6 dehydratase 2
- Alpha-L-fucosidase 1
- Putative GDP-L-fucose synthase 2
- GDP-mannose 4,6 dehydratase 1
- GDP-L-fucose synthase 1
- Polynucleotide 3'-phosphatase ZDP
- Transcription factor bHLH140
- Probable hexokinase-like 2 protein
- Hexokinase-4
- Hexokinase-like 1 protein
Sequence:
MSKQRKKADLATVLRKSWYHLRLSVRHPTRVPTWDAIVLTAASPEQAELYDWQLRRAKRMGRIASSTVTLAVPDPDGKRIGSGAATLNAIYALARHYEKLGFDLGPEMEVANGACKWVRFISAKHVLMLHAGGDSKRVPWANPMGKVFLPLPYLAADDPDGPVPLLFDHILAIASCARQAFQDQGGLFIMTGDVLPCFDAFKMTLPEDAASIVTVPITLDIASNHGVIVTSKSESLAESYTVSLVNDLLQKPTVEDLVKKDAILHDGRTLLDTGIISARGRAWSDLVALGCSCQPMILELIGSKKEMSLYEDLVAAWVPSRHDWLRTRPLGELLVNSLGRQKMYSYCTYDLQFLHFGTSSEVLDHLSGDASGIVGRRHLCSIPATTVSDIAASSVILSSEIAPGVSIGEDSLIYDSTVSGAVQIGSQSIVVGIHIPSEDLGTPESFRFMLPDRHCLWEVPLVGHKGRVIVYCGLHDNPKNSIHKDGTFCGKPLEKVLFDLGIEESDLWSSYVAQDRCLWNAKLFPILTYSEMLKLASWLMGLDDSRNKEKIKLWRSSQRVSLEELHGSINFPEMCNGSSNHQADLAGGIAKACMNYGMLGRNLSQLCHEILQKESLGLEICKNFLDQCPKFQEQNSKILPKSRAYQVEVDLLRACGDEAKAIELEHKVWGAVAEETASAVRYGFREHLLESSGKSHSENHISHPDRVFQPRRTKVELPVRVDFVGGWSDTPPWSLERAGYVLNMAITLEGSLPIGTIIETTNQMGISIQDDAGNELHIEDPISIKTPFEVNDPFRLVKSALLVTGIVQENFVDSTGLAIKTWANVPRGSGLGTSSILAAAVVKGLLQISNGDESNENIARLVLVLEQLMGTGGGWQDQIGGLYPGIKFTSSFPGIPMRLQVVPLLASPQLISELEQRLLVVFTGQVRLAHQVLHKVVTRYLQRDNLLISSIKRLTELAKSGREALMNCEVDEVGDIMSEAWRLHQELDPYCSNEFVDKLFEFSQPYSSGFKLVGAGGGGFSLILAKDAEKAKELRQRLEEHAEFDVKVYNWSICI
Protein: BZIP domain-containing protein (A7S1X3)
Organism: Nematostella vectensis (Starlet sea anemone)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- BZIP domain-containing protein
Sequence:
MKYTSTSQVAWKDFMKKVDSCIKDFYDCFKLQKNFILLRKSSRDSFLGDLSHWASIFVPRETITLQLLLCSLDNRLPKKGLNISDNSTDDYYPKKSCQLLSQILAVKPLWSSAYSVHRAVKLESDINACELTVPYSLIDPQRNLEKFGTEKYEIHKENRLKYPSKSAITEPPENLNSVFRASGAYKLKEGFTPSDCPELLGVESENLNTANGQFNRDIDLEQLTDKTFYEDFPVLRETASTKSEEPPSSSLSLTNTLDEMETDKIMGDGFFEEYMDLSLFPGLDLDLLGSSQALPDICPSSMNDVCQSAIDNVQELEDIIADELPAFLFQEGDGPDLDVKVEVIDEAPSPIDQEITELLSSCLSSPVSDISDSAAFSIPAVDVENTEVEVEDLLKILAADPVTEAIQVIAAVQEHSTIEVEQLGFASAASLGPSISAECPAITKTEKENQKCRKRKCPTSDDELPAKRINTFSRDTKASTSIDKATERRIKNNIASRHTRAARRQREQELFEKEEYLKKNNEELKQQIVELTKETEILRKLVIQRLSSVNSA
Protein: Guanylin (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Guanylate cyclase-activating protein I) (GCAP-I) [Cleaved into: HMW-guanylin; Guanylin] (Q02747)
Organism: Homo sapiens (Human)
Function: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Subcellular location: Secreted.
Interaction partners:
- Guanylyl cyclase C
- Atrial natriuretic peptide receptor 3
- Emerin
- Transmembrane and immunoglobulin domain-containing protein 1
- Guanylate cyclase activator 2B
- cGMP-dependent protein kinase 2
- Cystic fibrosis transmembrane conductance regulator
- Guanylyl cyclase-activating protein 2
- Retinal guanylyl cyclase 1
- Membrane-spanning 4-domains subfamily A member 12
Sequence:
MNAFLLSALCLLGAWAALAGGVTVQDGNFSFSLESVKKLKDLQEPQEPRVGKLRNFAPIPGEPVVPILCSNPNFPEELKPLCKEPNAQEILQRLEEIAEDPGTCEICAYAACTGC
Protein: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56) (P09914)
Organism: Homo sapiens (Human)
Function: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19008854, ECO:0000269|PubMed:21642987}.
Interaction partners:
- Interferon-induced protein with tetratricopeptide repeats 3
- Antiviral innate immune response receptor RIG-I
- Interferon-induced, double-stranded RNA-activated protein kinase
- Ubiquitin-like protein ISG15
- Interferon-induced GTP-binding protein Mx1
- Eukaryotic translation initiation factor 3 subunit E
- Interferon-induced helicase C domain-containing protein 1
- Interferon-induced protein with tetratricopeptide repeats 2
- Interferon-induced protein 44
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
Sequence:
MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP
Protein: Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1) (P31597)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine (By similarity). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (By similarity). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity). Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport (By similarity). Negatively regulated by ARL6IP5 (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:1280334}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P43003}. Apical cell membrane {ECO:0000250|UniProtKB:P43005}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P43003}. Synapse, synaptosome {ECO:0000250|UniProtKB:P51906}. Early endosome membrane {ECO:0000250|UniProtKB:P51906}. Late endosome membrane {ECO:0000250|UniProtKB:P51906}. Recycling endosome membrane {ECO:0000250|UniProtKB:P51906}.
Interaction partners:
- Amino acid transporter
- Amino acid transporter
- Solute carrier family 15 member 1
Sequence:
MGKPARKGCDSKRFLKNNWLLLSTVVAVVLGIVIGVLVREYSNLSTLDKFYFAFPGEILMRMLKLVILPLIVSSMITGVAALDSNVSGKIGLRAVLYYFCTTIIAVILGIVLVVSIKPGVTQKVDEIDRTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTTREEVTASDDTGKNGTEESVTAVMTTAVSENRTKEYRVVGLYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMVTVLSGLAIHSIVILPLIYFIVVRKNPFRFAMGMTQALLTALMISSSSATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISVTATAASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTVVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFALESATLDNEDSDTKKSYINGGFAVDKSDTISFTQTSQF
Protein: MyBP-C slow (G0YZM8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MPEPTKKEENEVSAPAPPPEEPNKEKEAGTAPAKEEDEASPPSALPPGLGSRALERKDSEWSLGESPAGGEEQDKQNANSQLSTLFVEKPQTGSVKVGANITFVAKVRAEDLLRKPTVKWFKGKWMDLASKAGKHLQLKETFERQTRVYTFEMQIIKAKENYAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPEIDVWELLKNANPNEYEKIAFQYGITDLRGMLKRLKRMRRVEKKSAAFAKILD
Protein: Peroxisomal membrane protein 11A (Peroxin-11A) (AtPEX11a) (Q9FZF1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in peroxisomal proliferation. Promotes peroxisomal duplication, aggregation or elongation without fission.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:17220199, ECO:0000269|PubMed:20179140}; Multi-pass membrane protein {ECO:0000269|PubMed:17220199, ECO:0000269|PubMed:20179140}.
Interaction partners:
- Peroxisome biogenesis protein 3-1
- Peroxisomal membrane protein 11C
- Peroxisome biogenesis protein 3-2
- Peroxisome biogenesis protein 16
- Peroxisome biogenesis protein 19-2
- Peroxisome biogenesis protein 19-1
- Peroxisomal membrane protein PEX14
- Peroxisome biogenesis protein 12
- Stress-response A/B barrel domain-containing protein UP3
- Butanoate--CoA ligase AAE1
Sequence:
MATKAPEKITKPKDRDFLNHLETYLSKRDGVDKLLKISRYATKIILASSLIPETRSIIPRLKSFESSVGVSRKAFRLGKFVQDINALRSSRWDSNHELVLLIIAYGGEGLYYFVEQFIWLTKSGLIDAKHSKWLQKISAWAELVGYVGSVSIKIRDLRKLNDEESCVASTIEISVSRGLACDGEDEKMKMIKEKKTLKVLSILQDLADGLMTIADIRDGKGVLSAPNVISSAGLFSAIVSTHKNWISC
Protein: Putrescine-binding periplasmic protein SpuD (Q9I6J1)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Putrescine-binding protein probably required for putrescine uptake into cells. Binds putrescine with high affinity (KD=3 nM), spermidine with relatively low affinity (KD=6.8 uM). Does not bind cadaverine or spermine. Putrescine binding induces large inter-domain conformational changes.
Subcellular location: Periplasm {ECO:0000255|PIRNR:PIRNR019574}.
Interaction partners:
- Polyamine transport protein PotH
- Putrescine transport system permease protein PotI
- Spermidine/putrescine import ATP-binding protein PotA
- Polyamine transport protein PotC
- Spermidine/putrescine transport system permease protein PotC
- Spermidine/putrescine transport system permease protein PotC
- Putrescine--pyruvate aminotransferase
- Polyamine transport protein PotB
- Probable permease of ABC transporter
- Probable permease of ABC transporter
Sequence:
MMKRFGKTLLALTLAGSVAGMAQAADNKVLHVYNWSDYIAPDTLEKFTKETGIKVVYDVYDSNEVLEAKLLAGKSGYDVVVPSNSFLAKQIKAGVYQKLDKSKLPNWKNLNKDLMHTLEVSDPGNEHAIPYMWGTIGIGYNPDKVKAAFGDNAPVDSWDLVFKPENIQKLKQCGVSFLDSPTEILPAALHYLGYKPDTDNPKELKAAEELFLKIRPYVTYFHSSKYISDLANGNICVAIGYSGDIYQAKSRAEEAKNKVTVKYNIPKEGAGSFFDMVAIPKDAENTEGALAFVNFLMKPEIMAEITDVVQFPNGNAAATPLVSEAIRNDPGIYPSEEVMKKLYTFPDLPAKTQRAMTRSWTKIKSGK
Protein: AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) (HBV X-associated protein 2) (XAP-2) (Immunophilin homolog ARA9) (O00170)
Organism: Homo sapiens (Human)
Function: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.
Subcellular location: Cytoplasm.
Interaction partners:
- Heat shock protein HSP 90-beta
- Aryl hydrocarbon receptor
- Heat shock protein HSP 90-alpha
- Prostaglandin E synthase 3
- Proto-oncogene tyrosine-protein kinase Src
- Aryl-hydrocarbon-interacting protein-like 1
- Mitochondrial import receptor subunit TOM20 homolog
- Aryl hydrocarbon receptor nuclear translocator
- Aryl hydrocarbon receptor repressor
- PRAME family member 10
Sequence:
MADIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIFHMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVVEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH
Protein: AT3g24160/MUJ8_16 (Type 1 membrane protein) (Type 1 membrane protein, putative) (Q9ZSJ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- B3 domain-containing protein At4g02870
- F2401.10
- 2-oxoglutarate
Sequence:
MKAFYVFVVALLLTLNYRGEASGSVFFIDGSNNQYLRPRSSSEALPMSPVEISAAVSALLGFAPSATLTADGSSKLNKILKPNPFERPRAAFVLEIAGADDMLLETSPSHSFLGNAIRSSIKSDSYKADTELPDNEVVVVSVNEPSSDVTDKDINDFASWLGGSYVAGAEPSSGLLSIPLAGGANVEFNLEKEAERKFALNLLGLYQNIRQAVSVYDDLSHGIDRTAELTVGRFGGIDALAQEYGQGMAKQGMDVLLSTLSKLFNLLETSHKGQIVGVIVLDERVNQESENLLNFGSSRSSARSMVEVEGIPSAAIIAEVILVRLTLAWLTGIILLIATILGVYFLMNMPLTKDTLLYSNVKLD
Protein: Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) (Q9NY33)
Organism: Homo sapiens (Human)
Function: Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin. Also cleaves Arg-Arg-beta-naphthylamide (in vitro).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:1515063, ECO:0000269|PubMed:3233187}.
Interaction partners:
- Kelch-like ECH-associated protein 1
Sequence:
MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA
Protein: Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Q8R527)
Organism: Mus musculus (Mouse)
Function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Interaction partners:
- Exocyst complex component 7
- Golgi-associated PDZ and coiled-coil motif-containing protein
- Adapter molecule crk
- Intersectin-1
- Cdc42 effector protein 4
- Cdc42 effector protein 3
- Crk-like protein
- Intersectin-2
- Exocyst complex component 4
- Cdc42 effector protein 2
Sequence:
MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPVCVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
Protein: Mediator of RNA polymerase II transcription subunit 7 (Q6IAZ5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364060}.
Interaction partners:
Sequence:
MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKTEPMDADDSNNCTGQNEHQRENSGHRRDQIIEKDAALCVLIDEMNERP
Protein: RAC-beta serine/threonine protein kinase (EC 2.7.11.1) (Q8I4W3)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Gametocyte-specific protein
- AP2 domain transcription factor AP2-FG, putative
- non-specific serine/threonine protein kinase
- cAMP-dependent protein kinase regulatory subunit
Sequence:
MNHINFFKCFSERNREKNNIPSYTSDSTQQQKKKKDYKKYFNFLITKKNKRETHKSTNGEEDYEHILYKNKTNVNIKEDNLKKDFDEYKEKKVNINGNVNNKKYSDKTTHINSVMTLEKNMILNNDNNTLNNNKKKKKKKKKKKKKSYSVEGTKLLKIKEYKKRKFFKIHFFLNRKNKNNDKREDPSKNIHDKRDISLEKNIINYNKYDMQFSFESVASNNINNNTHFKKDKKIINLKKYNNAHRDLYKNNYTNVFLCKKSFSDDEYKNKNIINNDSPCKFQKQNYDSKSKQGIYKANYRRFRDSCRQKLDLYKIHNRRNDVLFYGKGALKEIKKSMFDENKENAFYKDNMANCALNNMDNKNRMENECLYKYDEKEEIGKKRLRNSMSLSYERKKRIRPESFNYLKVIGEGSYGKVMLVKHVQNKKLYAMKILRKENILSRNQLEHTKVERNILKCVSHPFIVKMYYAFQTKQKLYFILEYCPGGELFFHLSKLREFSEETAKFYSSEIILALEYLHDLNIIYRDLKPENVLLDELGHIRLTDFGLSKEGITETNLTKSLCGTPEYLAPEIIEQKGHGKAVDWWSLGIMLYEMLTGELPFNNTNRNVLFESIKYQKLNYPKNLSPKAVDLLTKLFEKNPKKRLGSGGTDAQEIKKHPFFKNINWNDVLYKKVKPPFKPKLFNQLDLQNFDKQFLNMPLKYSDQHENTNITFADPKNFVVQDFNYNYYEFSGQQK