wanglab/gogpt-training-data huggingface dataset:
Protein: Sad1 and UNC84 domain containing 1 (A0A8I6APF3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004540}.
Interaction partners:
Sequence:
MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRGASFYLDRTLWLAKYTSSSFASFIVQLFQVVLMKLNFESETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTTTHSQLSQPHRAAGAMGRLCTYTGDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ
Protein: CBL-interacting serine/threonine-protein kinase 21 (EC 2.7.11.1) (SNF1-related kinase 3.4) (SOS2-like protein kinase PKS23) (Q94CG0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
Interaction partners:
- Calcineurin B-like protein 2
- Calcineurin B-like protein 3
- Calcineurin B-like protein 4
Sequence:
MGLFGTKKIGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYSGAAVDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNILDPNPLSRITLAEIIIKDSWFKIGYTPVYHQLSDSIKDNVAEINAATASSNFINAFQIIAMSSDLDLSGLFEENDDKRYKTRIGSKNTAQETIKKIEAAATYVSLSVERIKHFKVKIQPKEIRSRSSYDLLSAEVIEVTPTNCVIEISKSAGELRLYMEFCQSLSSLLTAEVS
Protein: Sphinx1 (Q8IQ79)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Spaetzle-processing enzyme
- Serine protease grass
- Sphinx2, isoform B
- trypsin
- Modular serine protease
Sequence:
MKLVVTLLVLSLTVSVGEKNKLSPRIAGGYRAKTFTIIYLVGIVYFKSQTSSLNYGAGTIISNQWILTVKTVLKYSYIEVHLASRRSYRGFDIIRIYKENFRFHYDNDHVIALVKCPYQKFDRRMDRVRVPAYDTRFERYVGNMTMVCGYGTEKRHAKLPEWMRCIEVEVMNNTECAKYYTPLKWYEMCTSGEGFKGVCEGDIGGAVVTMGPNPTFIGIIWLMPENCSIGYPSVHIRVSDHIKWIKRVSGVGF
Protein: Protocadherin alpha-9 (PCDH-alpha-9) (Q91Y11)
Organism: Mus musculus (Mouse)
Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular location: Cell membrane {ECO:0000303|PubMed:11230163}; Single-pass type I membrane protein {ECO:0000303|PubMed:11230163}.
Interaction partners:
Sequence:
MRLGNRPEDIRTCVHLRWHIHGLLRQENASVVISKCLRHGAWRLLLWLLLLATWDVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVVSKDRGDLLEVNLQNGILFVNSRIDREELCGQNAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPIFSVAEQKILVAESRLLDSRFPLEGASDADVGENSMLTYKLSSNEFFILDIVNKRGKGKFPVLVLRKLIDREENPQLKLLLTATDGGKPEFTGSVSLLIQVLDVNDNAPVFDRSVYEVKMYENQENKTLVIWLNATDSDEGINKEVEYSFSSLASSIIRQKFLINEKTGEIKINGAIDFEESNNYEIHVDATDKGYPPMVAHCTVLVEILDENDNAPEIVLTSLSLPVKEDAPLGSVIALISVSDKDSGVNGQVTCSLTNHVPFKLVSTFKNYYSLVLDSALDRETTADYKVVVTARDGGSPSLWATASVSVEVADVNDNAPAFAHPEYTVFVKENNPPGVHIFTVLAVDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVQDENDNPPTLLGHQSGGPAGEFSQLVSRSVGAGHVVSKVRAVDADSGYNAWLSYELHPTVGARSPFRVGLYTGEISMTRALDESDLPRQRLLVLVKDHGEPMLIATATVLVSLVENGQVPKASSQGLPNSSRREASLMDVNVYLIIAICAVSSLLVLTLLLYTALRCSAVPMQAGCGLGKPTLVCSSAVGTWSYSQQRQQRVCSGEGPPKTDLMAFSPSLTPCPVAEVGMESHSVGGDVPGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Protein: Histone H2B type 1-L (Histone H2B.c) (H2B/c) (Q99880)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H3.2
- Histone H3.1t
- Histone H3.1
- Histone H4
- E3 ubiquitin-protein ligase BRE1A
- Histone H3.3
- Histone H2B type 1-A
- Histone H2A type 2-C
- HLA class II histocompatibility antigen, DRB1 beta chain
- HLA class II histocompatibility antigen, DR alpha chain
Sequence:
MPELAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
Protein: PSP1 C-terminal domain-containing protein (Q389Y5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQHQLREEQMRATLKQLQTDVNELLDDQEQYIRFVYGKIRGQLERMHHMIASGGDAATALGNCSSYLGSMDHLTQAYTGCMTDGQRSGAAGGCSLPAASTPLSERIQGMLPPLRNLMMEGLTQTDCTQWAALTTAPGHEDSPTKSPQKQWGDEGQVCSAVNAAVDYTCFDPIGSVGGDDDLQQSAEGSLLSPYACGDDLRHEQLHQGDLIGQGTKADVIHIGTINSLSNQHVTTSVRVEYVNGRPKAVSIPDGAPEDPERLGIDVHSPCKVMVEFKRKRVLQFESKEYVPPGSCVVVGGDRGEDIGLVTYTWCETTRPLSGGVDTSCASDTTNGSVGSKGVVVGVGLAGSAFTRNIGLGSGTVLRLADESDVTQLHTVQVELERRAIDVCSQRVLERGLPMTIVDAEYQFDKNKLTFFYEAQQRMDFRELVRDLYKTFRARIWMEAVEN
Protein: Protein downstream neighbor of Son (B17) (Q9NYP3)
Organism: Homo sapiens (Human)
Function: Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra-S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability.
Subcellular location: Nucleus {ECO:0000269|PubMed:28191891}. Note=Localizes at DNA replication sites. {ECO:0000269|PubMed:28191891}.
Interaction partners:
- DNA primase large subunit
- DNA polymerase delta subunit 2
- Trifunctional purine biosynthetic protein adenosine-3
- DNA polymerase alpha subunit B
- DNA polymerase delta catalytic subunit
- DNA polymerase alpha catalytic subunit
- DNA primase small subunit
- Replication protein A 70 kDa DNA-binding subunit
- Replication protein A 32 kDa subunit
- Replication protein A 14 kDa subunit
Sequence:
MALSVPGYSPGFRKPPEVVRLRRKRARSRGAAASPPRELTEPAARRAALVAGLPLRPFPAAGGRGGGSGGGPAAARRNPFARLDNRPRVAAEPPDGPAREQPEAPVPFLDSNQENDLLWEEKFPERTTVTELPQTSHVSFSEPDIPSSKSTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGLVQHCRATEVTLPKSIQDPKLSSELRCTFQQSLIYWLHPALSWLPLFPRIGADRKMAGKTSPWSNDATLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTVLFRAAGLAGSDLITALISPTTRGLREAMRNEGIEFSLPLIKESGHKKETASGTSLGYGEEQAISDEDEEESFSWLEEMGVQDKIKKPDILSIKLRKEKHEVQMDHRPESVVLVKGINTFTLLNFLINSKSLVATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRDQFSLEITGPIMPHSLHSLTMLLKSSQSGSFSAVLYPHEPTAVFNICLQMDKVLDMEVVHKELTNCGLHPNTLEQLSQIPLLGKSSLRNVVLRDYIYNWRS
Protein: Monopolar attachment protein 1 (Meiotically up-regulated gene 159 protein) (Q9UTI4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays an important role in chromosome segregation during meiosis I by allowing meiotic rec8 to establish cohesion at the centromeric central core and thereby promote the side-by-side structure of kinetochores at meiosis I. Enables monopolar attachment during meiosis I. Required to facilitate kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Acts in collaboration with plo1.
Subcellular location: Nucleus. Chromosome, centromere {ECO:0000269|PubMed:16325576}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:16325576, ECO:0000305|PubMed:25533956}. Note=Localizes to the centromere. Does not require rec8 for centromeric localization but instead cnp3. {ECO:0000269|PubMed:16325576}.
Interaction partners:
- Inner kinetochore subunit cnp3
- Meiotic recombination protein rec8
- Sporulation-specific protein 13
- Monopolin complex subunit pcs1
- Serine/threonine-protein kinase plo1
- Meiotic recombination protein rec12
Sequence:
MAINNENELEYKLIKKNKNPKISNSKKKNSTRPALQDKTNQTLPIHQNQAFSNILPSDFSIIKTPETKTADDFPVNGYEGLNILKFDLELFYKLKPVATSTPKSCMRTGSNLFLNETVKHVPDERLVSNIKNTQTKDSITRDSAYYHRKTMTESIIKTLAAFDAEVDEIILF
Protein: Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5) (Q62862)
Organism: Rattus norvegicus (Rat)
Function: Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis (By similarity).
Subcellular location: [Isoform Beta]: Cytoplasm, cytosol.; SUBCELLULAR LOCATION: [Isoform Alpha-1]: Membrane. Note=The alternatively spliced exon in alpha isoform resemble conserved sequences that mediate interactions with the cytoskeleton, thereby explaining the differential localization.; SUBCELLULAR LOCATION: [Isoform Alpha-2]: Membrane. Note=The alternatively spliced exon in alpha isoform resemble conserved sequences that mediate interactions with the cytoskeleton, thereby explaining the differential localization.
Interaction partners:
- Mitogen activated protein kinase kinase kinase 3
- Mitogen-activated protein kinase 7
- mitogen-activated protein kinase kinase kinase
- SKI family transcriptional corepressor 1
- BTB/POZ domain-containing protein 9
- Mitogen-activated protein kinase kinase kinase 4
- A-kinase anchor protein 6
Sequence:
MLWLALGPFRAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHTSPVVSDSLPSNSLKKSSAELRKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKIPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTSGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPLGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNATVVSMWVCRALEERRSQQGPP
Protein: Uncharacterized protein At5g13720 (Uncharacterized protein family (UPF0114)) (Q9FNA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Keratin-associated protein, putative
- At5g62720
- AT5g24690/MXC17_8)
- Plastidal glycolate/glycerate translocator 1, chloroplastic
- 1-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic
- ADP,ATP carrier protein 2, chloroplastic
- Protein root UVB sensitive 1, chloroplastic
- ABC1 family protein
- Dicarboxylate transporter 2.2, chloroplastic
Sequence:
MALSSLISATPLSLSVPRYLVLPTRRRFHLPLATLDSSPPESSASSSIPTSIPVNGNTLPSSYGTRKDDSPFAQFFRSTESNVERIIFDFRFLALLAVGGSLAGSLLCFLNGCVYIVEAYKVYWTNCSKGIHTGQMVLRLVEAIDVYLAGTVMLIFSMGLYGLFISHSPHDVPPESDRALRSSSLFGMFAMKERPKWMKISSLDELKTKVGHVIVMILLVKMFERSKMVTIATGLDLLSYSVCIFLSSASLYILHNLHKGET
Protein: LIM/homeobox protein Lhx3 (LIM homeobox protein 3) (Homeobox protein LIM-3) (Q90421)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Insulin gene enhancer protein isl-1
- PROP paired-like homeobox 1.
- LIM domain-binding protein 1-A.
- POU domain protein
- Visual system homeobox 2
- Oligodendrocyte lineage transcription factor 2.
- LIM domain-binding protein 1-A
- NK6 homeobox 1.
- Insulin gene enhancer protein isl-2a
- LIM domain-binding 2a.
Sequence:
MLLEHPGSSCQNAGNYTRYSSSQDIPVCAGCNQHIVDRFILKVLDRHWHSKCLKCSDCQSQLADKCFSRGDSVYCKDDFFKRFGTKCAACQQGIPPTQVVRRAQDFVYHLHCFACIVCKRQLATGDEYYLMEDSRLVCKADYETAKQREADSTAKRPRTTITAKQLETLKNAYNNSPKPARHVREQLSTETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGTSKSDKDSTQEDGMDSDAEVSFTDEPPMSDLGHSNGIYSSLSESSPALSRQGGNHPAFPLEHGAIIPSQEPYHDIQASSPYSLPQSPGPLQPLPRHQPLISSLVYPESGLPMAGQSGGQDMTPGVRMMAAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
Protein: Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) (hNR1) (Q05586)
Organism: Homo sapiens (Human)
Function: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
Subcellular location: Cell membrane {ECO:0000269|PubMed:26875626, ECO:0000269|PubMed:26919761, ECO:0000269|PubMed:28095420, ECO:0000269|PubMed:28105280, ECO:0000269|PubMed:28126851, ECO:0000269|PubMed:28228639, ECO:0000269|PubMed:38538865, ECO:0000269|PubMed:7685113}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P35439}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:P35438}. Postsynaptic density membrane {ECO:0000250|UniProtKB:P35439}. Synaptic cell membrane {ECO:0000250|UniProtKB:P35438}. Note=Synaptic cell membrane targeting is dependent of GRIN2B/GluN2B subunit (By similarity). Association with GRIN3A occurs in the endoplasmic reticulum (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:P35438, ECO:0000250|UniProtKB:P35439}.
Interaction partners:
- Glutamate receptor ionotropic, NMDA 2A
- Glutamate receptor ionotropic, NMDA 2B
- Glutamate receptor ionotropic, NMDA 2D
- Glutamate receptor ionotropic, NMDA 2C
- Glutamate receptor ionotropic, NMDA 3B
- Glutamate receptor ionotropic, NMDA 3A
- Disks large homolog 4
- Calmodulin-1
- Calmodulin-like protein 4
- Calmodulin-like protein 3
Sequence:
MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES
Protein: MFS-type transporter kojT (Kojic acid biosynthesis cluster protein T) (Kojic acid transporter) (Q2U5H8)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: MFS-type transporter; part of the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent. Involved in the seretion of kojic acid.
Subcellular location: Cell membrane {ECO:0000305|PubMed:20849972}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Transcription factor kojR
- Probable FAD-dependent monooxygenase kojA
Sequence:
MQSFRQYRRMRRDLQESIKLHGPYAAAGDRHVQPTDDILEDADDARLEKGIHSMNGHGQSPYSTPGIVLHDGQRVTVPGVNLRRASEICERVNTKTLFIVGFDGPDDQLNPKNWSIGRKWATLGIVGTTGMLVGWASSIDSTVIKQGQEAFGVSEVAESLATALFLFAFGFGSLVAAPFSETVGRNPVYIATLSILMIFTMASGLAPNFGAQLAFRFLAGLFGCTPMTTFGGSMADIFDPMDRTYAFPVCCTLSFLGPFLAPMVGAFIGQSTHISWRWTEWCTLIMAALVTGAIFLFVPETYGPVLLQWKAKQLREITGDPRFMAEIELRQTSLVTRLMHSCSRPFHLFFREIMVALFTMYLVVVYIVLFGFLTGYEFIFGRTYGFTQGSVGLTFIGMNIGFLIAFAMVPHIYFSYKKRLQNAIENGHNGLPPEERLWFAMYGAPWLPISLFWMGWTSYPSISYWSPLVASVAFGFSVQGIFISTYQYLIDTYELFAASALVSATFFRYIAAGAMVIVSIPMYGNLGVHWSLTLLGCISVLMTPVPYIFYKYGHVIRQRNKKTP
Protein: Mitochondrial MRF1 N(5)-glutamine methyltransferase MTQ1 (EC 2.1.1.297) (P53944)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Methylates MRF1 on 'Gln-287' using S-adenosyl L-methionine as methyl donor.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16321977}.
Interaction partners:
- Multifunctional methyltransferase subunit TRM112
- Peptide chain release factor 1, mitochondrial
- eRF1 methyltransferase catalytic subunit MTQ2
- Uncharacterized peptide chain release factor-like protein YLR281C
- Leucine--tRNA ligase, mitochondrial
- Formate dehydrogenase 1
- Protein arginine N-methyltransferase 2
- Ribosomal lysine N-methyltransferase 5
Sequence:
MPRISTSLIRKASRIRPGLHLLLPECRTLEQAKLEYKWLTEELPPDKSIRWACLQRYKHVPLQYILRSQPFGALDIVCKPGVLIPRWETEEWVMAIIRALNNSMLSRHTIPLHICDTFTGTGCIALALSHGIANCTFTAIDVSTRAIKLVKENMLKNKVSGGKLVQHNILSSKASDEYPSHIDILTGNPPYIRKRDFNRDVKTSVKLFEPRLALVGELECYINLVNYWLPKTDSFFYEIGDVEQFNYVERRIKEDSYLSRIWSIGLKYDSNGKARVVYGFKATPKGRILHQIFASFGTIRHLATALSGHKANCN
Protein: Antithrombin-III (Serpin C1) (F7EY53)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Interaction partners:
Sequence:
RYQAGHGSVPCRKLCLLSLLLIGALGCAVCHGNPVDDICIAKPRDIPVNPMCIYRSPAKKATEEDVLEQKVPEATNRRVWELSKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNNTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSNLVSANRLFGDKSLTFNESYQDVSEIVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAIDELTALVLVNTIYFKGLWKSKFSPENTRKEPFHKVDGQSCLVPMMYQEGKFKYRRVGEGTQVLEMPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDELSEVMLVVHVPRFRIEDSFSLKEQLQDMGLVDLFSPEKSQLPGIIAEGRDDLFVSDAFHKAFLEVNEEGSEAAASTSVVITGRSLNPSRVTFKANRPFLVLIREVALNTIIFMGRVSNPCVN
Protein: Vacuolar protein sorting-associated protein vps5 (Q9C0U7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for efficient sporulation target of PtdIns(3)P in vesicle transport required for onset of the forespore membrane formation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi apparatus {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- Vacuolar protein sorting-associated protein 17
- Vacuolar protein sorting-associated protein 26
- Vacuolar protein sorting-associated protein 35
- Vacuolar protein sorting-associated protein 29
- Sorting nexin-3
- Vacuolar protein sorting/targeting protein 10
- Protein transport protein yif1
- Vacuolar protein sorting-associated protein 27
Sequence:
MLGHNIYEEDDAFNPFADSVSPLNPPKTDQEPSAEGVEEESPNVQASPPKTHIYTSPRKRSVNLKSLPFETLTLDSAPLGPLQFSDAPSMAPENNRLEVGLNTKINPLKGSSPALNADFSANKPWISEVNSFSPSPIGATENPTIPNSEQTVDTLDAASSSAPNFTHTVSSASSQKQGSTSLTDTENQKAHPAAAPQSLTPFYIQVHDPHTVKEITKSHTVYSVSTRLEEHNQPSVSNVTVQRRYNDFAFLYQLLSNNHPGCIIPPIPEKQVVGRFDDEFIEQRRAALEVMLRKISAHPVLRDDYSFKLFLEAETFDPRMTHRTTLIESSSSPLRSGPSTSGLLDSFTSAFHTSGSSKFSEQDPILIEAKDTLDSLETQLKSVYHALLLSIDQRIQFASAIHDFGEAVGNLSLVDLEPTLSSKFDGLSQLQVELRFVQERKVAQDNLTLGTTLEEYIRYVESAKNAFTTRQKLWQTWQSSVQAVSRAKTQLEKCKKQAKSQQKSLPYLEEQYEKYRAKAADLEKEFSESTTLLKRDLSSLTTSRVDDLKASVETWLESAIESQKEIIERWESFLDQ
Protein: Tubulin-specific chaperone D (Q7KN66)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAAVVLPQLLAKTDTIDINCRHGCVLAMGEITLTLRKLEEKSDPQVVYLSNQRVAELNELIITFLDKNFYRGMSGDLMKSCTSSYIKNCSLAKLQATPECLVSWQKVIDSCLITKSNAIRDGAVEAFGELCTTYYCSDSRHGENEAIINTYLTGADNDLEEHIRMGYIAALGVLPSFMIRCHLQAILDSLVKHSLTPLQAVLVGEMGDRENIQAYRWSEARTQSVLALTKLVKTVGYGGGIDSFAEPKNFNKVIECLLRALQEYTLDNRGDIGAWVREAAMSSLYEIVTTCPPDLLAPEQVHEIVVGFMQQAVEKIDRTRGLGGRLCCQLIHHQPRIPYIREHSKLLEIFPADADSVLWLFADHTFPLFCELLSLPDYSKRVLLGLSASIGQLTESLIKYASSALFHFLRSNPETVPRLCSEVVQIFEEHLLNERVTYPLLSFLDILIGSGTVESVLHDEANPFAEDIFRLLNLEVKGYKKLYKTATSISAFCQLLQVPRLSKRILSKLSVFLGLQHVHVRKTAATKLYEALALHGDVTEVPEENMDEILTLLSETDWTQPLVEVRPLRNQLCQLMDIKPPVSGAAAAAALQQASADK
Protein: TAK1-binding protein (Q4TZQ4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAATPPMPPGSNTHQLNGKTVGKGNPLAEAINQHFQRKKQNQHQSPNPSPNPNPNSPASRSGSYEQLELLDHATHPQQQQEASSGKAKPSCHCTNISIMHLFHEMKQEFPTIPDAIVTQCVNENCHQRENCIQMLRKELALHPIPVQSYPAKVLQQQQQQHHQNRQAKPPTPLKPSRIAPPQPEAVLSNGVATPPGVGSPHPDTQPRPRPTTLNLQRQFSTQLQQKIMQRQQRQQRDHQPAQLTPTSLSKPLRRAPPLPPPPKPKPGSFSNDSSCLTSPMSSSESELSLNAVPLSSPTSAAATAAAASAAIASTQQQPSPVRHRSVITLQPEPPYARDFRSIDFPPTTACTPRLPSPSSAASPSAPGGRKSFTSLNLTLRQPTGSAQSAIDITAGPAPSGQGSGITYSSVSFDARRGTQKNFQLTVTDEGSVFSAGSVRPRTLYATPCEPVTSVPANQQPPPPAAVVADGLGDADMTSDVFPYPTQEQNHIVASNYSNNHAVSDNNNIGISNSTDSSPTMPLYEGVMEECDREARAATIERQKQRRDKLANALRDNKKRLLVLEQEINILTEPVPVGESERLDRDIKQLTEDCNRLLDCLNEPQANGPGPAANPTNRQHLLPASNASQQQPQQQPQPFPRQRQSARVQAPPSSLRLHSVPAAPNSQPVQDFGQHHSSAPTSACLTPQMQSQQQLLQLQQEPPPTYAQYYQFQQYLQQQRQQQLQQQMQQQQQLQQQMQQQQQPQPQQEEEFLSDSDVDEEEETLDSWACNMCTFRNHPQLNICEACENVRIQPGMIRIVPSGGGAAAAAATPPGSIEQQQQPSQQPYALHT
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (Q8SYF0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
Interaction partners:
Sequence:
MNSKSDYEAEKEKKLTITNRFGDSLENYELSNESEHKTHVYPKKIPNRKNGILKNTDANHSAVDNQHLEDVDLADILGTNWPKRAGPAAMILNNKSKTDPSNSVDLILKPASPILKIEPEEPLRFTIADYQPLIEIPGTELAIGSLVEVSNPGVCEDLYGVVRWIGIPPGPQKNVLVGIEVEDESNLKNVVASDGRHNGVRLFTCHDGRAIFVPANRCTADRRFADVDNSISANRVSSNHAKKFGVADCPAIYGSIPPLQIHNSDELASICGKFKGIQGHHNSCYLDATLFSMFTFTSVFDSILYRRPGPQDIRNYSEVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSGLTCEEKDPEEFLNSLLSQIMRVEPFLKLSSGQDSYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDCFGSLQAGSGLECTAFCPKCLKTFHSHIKRTNHVSKKIYSPKEFKIMAEHMVVPRLYMELFAVVCIETSHYVAFVKSGSGPDAPWCFFDSMADRKGEQNGYNIPEITCVPELTQWFSEEGARSINETSTNDKVLPEHAKRIFCDAYMCLYQSTDIMMYH
Protein: Transcriptional regulator GZF3 (Q5A201)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Probable transcription factor involved in response to fluconazole, LiCl, and copper.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histone deacetylase HDA1
Sequence:
MSMSDIQQRPQIPTTTTAAVAAAASTNVNTGAATTSTATTGNTPTTTPTSPIENISKVPVKPSVDVPVKPKLEQQQQQQSEQSSKPPPPPPEQQQQHQLPTPPIKPPKTGTTSSSSSTTTSSATSSKISMSGPVCGNCQTQTTPLWRRDETGQVLCNACGLFLKLHGRPRPISLKTDTIKSRNRVKQNGSNSQSSKSSGANTPELKSKEGKSGKKSPKSKKKSLGNGNGNGNSSHDHNTLTPLLPATSNNTPTFKSTTSQSQHQQNQNHHHQHHNHHHHLPNHVLQTHQVPLHYPSSTPTQFAPGLQRITSPLLLSTTSSSSSIRTEPNNNNTSKLTPIQAAAGALENMSNELGPSATFKKGNNINGISLMNKTKKDVSSINGSSTSLSSSSASSSIFSSVAPSTSSSSSLSNGTTINNPAPKLPTLGSKISSPSSQPFTRSTTPLQTLPPLHKIASHESSLPPLHNISTYNNNNSGGGADGGQQSMANYSQTNRSPINGNQDNNNNNNNNNNNNNNGNNNGNNNSNNNGNNFTASAHEVTLLKTRISELELVNDLYRTRIMELEAMEQAARLRENSMKKRLDEVMNLQINYQNLLNNNGGMSSQTQPQPSQQPQQAGQYYSNNNNNNNNDQGSQSISPNVSITGSTTITSPNSRSKIISETTPTHHQQQQGGVGAGDNESIILPPLKRNRTDELTDANGNGNGNDNKKVKI
Protein: Polypeptide N-acetylgalactosaminyltransferase (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase) (F1R7M5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU361242}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU361242}.
Interaction partners:
- Nucleoporin NUP188
- C1GALT1-specific chaperone 1
- Lysine
Sequence:
MGSVTLRYFCYGCLFTSVTWSILLFLYFNLSQESRLSFRNVPVQGQHRFQPRFTRGPAVQHRDGSQVRKGQALEAVKPDLSPELGMIFNKQDQEVRDMGYHKHAFNVLISNRLGYHRDVPDTRTDKCRDRAYSVSLPTASIVICFFNEAFSALLRTVHSVLDRTPNYLLHEIILVDDHSELDDLKEDLDSYVQQHLQKKVKVVRNEKREGLIRGRMIGASHATGEVLVFLDSHCEVNEAWLQPLLTPIKENRKTVVCPVIDIISADTLVYTPSPIVRGGFNWGLHFKWDPVPMSELNSPDGAIRSPTMAGGLFAMDRNYFYELGQYDRGMDIWGGENLEISFRIWMCGGQLLIVPCSRVGHIFRKRRPYGSPGGQDTMAHNSLRLAHVWMDDYKEQYFALRPELRNRDYGDISERVSIRKRLQCHSFKWYLDNIYPEMQVSSPHKPQQPVFINKGLKRPKVLQRGRLRNLLADKCLVAQGRPSQKGGAVVVKDCDPQDPEQEWAYDEEHELVLAGLLCLDMSEIRSSDPPRLMKCHGSGGSQQWTLGKKNWLYQVSVGQCLAVGDPLSIKGYVSMAICDDSRSQQWQLEG
Protein: BZIP domain-containing protein (A7S4U5)
Organism: Nematostella vectensis (Starlet sea anemone)
Interaction partners:
- BZIP domain-containing protein
- BZIP domain-containing protein
- BZIP domain-containing protein
- BZIP domain-containing protein
Sequence:
MNAAFQSMNPSHEHNNYELYTRTAMPVPVAEDSDRDSNISSEDTASFSEFSNPQTPPLKGPADGVKQELRNAIKCRRVAKGLEEMPHLDAKRPKVEELSPAELEKRRIRRERNKLAAFKCRQRRKEHIQELEIESEGIEDSNKELEREISELHEQRQQLEEMLKTHSCKLSNNNGGSRTKSNSCASAAAKSNSGSPTTPTGPIKA