wanglab/gogpt-training-data huggingface dataset:
Protein: NADH-ubiquinone oxidoreductase chain 3 (EC 7.1.1.2) (NADH dehydrogenase subunit 3) (P03897)
Organism: Homo sapiens (Human)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03898}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- Cytochrome c oxidase subunit 3
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase 1 alpha subcomplex subunit 5
- NADH-ubiquinone oxidoreductase chain 5
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
Sequence:
MNFALILMINTLLALLLMIITFWLPQLNGYMEKSTPYECGFDPMSPARVPFSMKFFLVAITFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILALSLAYEWLQKGLDWTE
Protein: Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (EC 2.4.99.19) (Protein glycosylation B) (B9KDD4)
Organism: Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060)
Function: Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (GalNAc(2)GlcGalNAc(3)Bac(NAc)(2) in eubacteria, where Bac(NAc)(2) is di-N-acetyl bacillosamine) from the lipid carrier undecaprenol-pyrophosphate to an asparagine residue within an Asp/Glu-Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000269|PubMed:21677752}.
Interaction partners:
- Protein translocase subunit SecY
- 50S ribosomal protein L3
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL22
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL14
Sequence:
MKLQQNFTDNNSIKYTCILILIAFAFSVLCRLYWVAWASEFYEFFFNDQLMITTNDGYAFAEGARDMIAGFHQPNDLSYFGSSLSTLTYWLYSILPFSFESIILYMSAFFASLIVVPIILIAREYKLTTYGFIAALLGSIANSYYNRTMSGYYDTDMLVLVLPMLILLTFIRLTINKDIFTLLLSPVFIMIYLWWYPSSYSLNFAMIGLFGLYTLVFHRKEKIFYLTIALMIIALSMLAWQYKLALIVLLFAIFAFKEEKINFYMIWALIFISILILHLSGGLDPVLYQLKFYVFKASDVQNLKDAAFMYFNVNETIMEVNTIDPEVFMQRISSSVLVFILSFIGFILLCKDHKSMLLALPMLALGFMALRAGLRFTIYAVPVMALGFGYFLYAFFNFLEKKQIKLSLRNKNILLILIAFFSISPALMHIYYYKSSTVFTSYEASILNDLKNKAQREDYVVAWWDYGYPIRYYSDVKTLIDGGKHLGKDNFFSSFVLSKEQIPAANMARLSVEYTEKSFKENYPDVLKAMVKDYNKTSAKDFLESLNDKDFKFDTNKTRDVYIYMPYRMLRIMPVVAQFANTNPDNGEQEKSLFFSQANAIAQDKTTGSVMLDNGVEIINDFRALKVEGASIPLKAFVDIESITNGKFYYNEIDSKAQIYLLFLREYKSFVILDESLYNSSYIQMFLLNQYDQDLFEQITNDTRAKIYRLKR
Protein: NAC domain-containing protein 91 (ANAC091) (TCV-interacting protein) (Q9LKG8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator essential for the anti-viral defense called virus basal resistance response pathway. Not involved in HRT-mediated hypersensitive response (HR) and resistance to TCV. Binds DNA non specifically. Activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353, ECO:0000269|PubMed:15629774}. Endomembrane system {ECO:0000269|PubMed:15629774}; Single-pass membrane protein {ECO:0000255}. Note=(Microbial infection) Nuclear localization is blocked by its interaction with the coat protein (CP) of turnip crinkle virus (TCV), thus leading to its accumulation in inclusion-like structures peripheral to the nuclei. {ECO:0000269|PubMed:15629774}.
Interaction partners:
- Protein S-acyltransferase 24
- Aquaporin TIP1-2
- Aquaporin TIP2-1
- Aquaporin TIP1-1
- PAMP-induced secreted peptide 1
- Probable aquaporin TIP5-1
- Aquaporin TIP3-1
- Probable aquaporin TIP2-2
- Putative aquaporin NIP4-1
- At5g42290
Sequence:
MKEDMEVLSLASLPVGFRFSPTDEELVRYYLRLKINGHDNDVRVIREIDICKWEPWDLPDFSVVKTTDSEWLFFCPLDRKYPSGSRMNRATVAGYWKATGKDRKIKSGKTKIIGVKRTLVFYTGRAPKGTRTCWIMHEYRATEKDLDGTKSGQNPFVVCKLFKKQDIVNGAAEPEESKSCEVEPAVSSPTVVDEVEMSEVSPVFPKTEETNPCDVAESSLVIPSECRSGYSVPEVTTTGLDDIDWLSFMEFDSPKLFSPLHSQVQSELGSSFNGLQSESSELFKNHNEDYIQTQYGTNDADEYMSKFLDSFLDIPYEPEQIPYEPQNLSSCNKINDESKRGIKIRARRAQAPGCAEQFVMQGDASRRLRLQVNLNSHKSETDSTQLQFIKKEVKDTTTETMTKGCGNFTRSKSRTSFIFKKIAAMGCSYRGLFRVGVVAVVCVMSVCSLVA
Protein: Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa) (Q9QY81)
Organism: Mus musculus (Mouse)
Function: Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000250}. Nucleus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Nucleoporin SEH1
- Nucleoporin 205
- Nuclear pore complex protein Nup214
- Nuclear pore complex protein Nup155
- Nucleoporin NUP35
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein Nup93
- Nucleoporin NUP188
- Nucleoporin NDC1
- E3 SUMO-protein ligase RanBP2
Sequence:
MARASLVQPALWALLLLQVVGPAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWSSTRPEVASIEPLGSSEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEANGFSDSHNALRILTFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLLVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPDPQGDPARPVAILTQDTSRVTAMQMGQSNLVLGHRSIRMQGASRLPNSTIYVVEAGYLGFTVYPGDRWVLETGHLYAITIEVFDRSSNKVYPSDNIRIEAVLPAEFFEVLSSSQNGSYHHIRAIQSGQTAISATLTSVVDQDGGVHVLQVPVWNQQEVDIHIPITLYPSILTFPWQPKTGAYQYTIKAHGGSGNFSWSSSSSMVATVTVKGVMTTSGDTGLSVIRAHDVQNPLHFGEMKVYVIEPSSMEFAPCQVEARVGHTLELPLTISGFMPGGGSEVVTLSDCSHFDLVVEVENQGVFQPLPGRLPPGPEHCSGVKVKADAQGSTTLLVSYTHGHVHLDAKITLAAYLPLKAVDPSSVAVVTLGSSKEMLFEGGPRPWVLEPSKFFRNVTSEDTGSISLSLLGPPASRNYQQHRVLMTCQALGEQVIALSVGNRPSLSNPFPAVEPTVVKSICAPPSRLTLMPVYALPQLDLSCPLLQQNKQVVPVSSHRNPLLDLGAYDQQGRRFDNFSSLSIQWESSRPLLASIELDQPMQLVSQDDGNGQKKLHGLQTVSVHEASGTTAISATATGYQQSHLSEARVKQPHDPLVPVSASIELILVEDVRVSPEEMTIYNHPGVQVELYITEGSGYFFLNTSTQDIIKVAYQDTRGVALVHPLLPGSSTVMVHDLCLAFPAPAKAIIHVSDIQELYVRVVDKVEIGKAVKAYVRVLDFYKKPFLAKYFTFMDLKLQAASQIITLVTLDEALDNYTATFLVHGVAIGQTSLSASVTDKSGQRVSSTPQQIEVFPPFRLIPRKVTLIIGAMMQITSEGGPQPQSNILFSINNESVAAVSSSGLVRGLMVGNGSVLGVVQAVDAETGKVIIVSQDLVEVEVLQLQAVRIRAPITRMRTGTQMPVFVTGITSNQSPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEVSIRLPPQYNFAMNVYGRVKGRTGLRVVVKALDPTAGQLHGLGKELSDEIQIQVFEKLRLLNPEIEAEQILMSPNSFIKLQTNRDGAAILSYRVLDGPEKAPIVHTDEKGFLVSGSGIGVSTLEVIAQEPFGTNQTILVAVKVSPVSYLRISMSPVLHTQHKEALTALPLGMTVTFIVHFHDSSGDIFHAHNSVLNFATNRDDFVQIGKGATNNTCIIRTVSVGLTLLHVWDVEHLGLSDFVPLPVLQAITPELSGAVVVGDILCLASVLTSLGGVSGTWSSSASHVLYVDPKTGVAIARDAGSVTVYYEIAGQLKTFKEIVVGTPQKIVARRLHSAQTSIQEATASKVTVSVGDRSSNLLGECSPAQREAIEALHPESLISCQLQFKQDVFDFPACDVFTVEPGFDAALGQYLCSVTMRRLTDKQLKHLNMKKTSLAVTASIPSSYTSVEKVGAEVPFSPGLYANQAEILLSNHYTSSEVKVFGAVESLENLEVKSGSPAVLAFVKEKSFGLPSFITYTVGVLDPTAGSQGPLSTALTFSSPATNQAITIPVTVAFVLDRRGPGPYGASLLSHFLDSYQVMFFTFFALLAGTAVTIIAYHTVCAPRELASPLALTPRASPQHSPHYLASSPAAFNTLPSGRKASPPSGLWSPAYASH
Protein: Apoptosis-linked gene 2-interacting protein X 1 (Prion-like-(Q/N-rich) domain-bearing protein 58) (Protein YNK1) (P34552)
Organism: Caenorhabditis elegans
Function: Required for lin-12 degradation after it has been internalised in the vulval precursor cells.
Interaction partners:
- Charged multivesicular body protein 4b
- Charged multivesicular body protein 4b
- Multivesicular body subunit 12A
- Tumor susceptibility gene 101 protein
- EF-hand domain-containing protein
- Dynamin-type G domain-containing protein
- Signal transducing adapter molecule 1
- Hepatocyte growth factor-regulated tyrosine kinase substrate
- vesicle-fusing ATPase
Sequence:
MATFGFLSAPLKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIYIKGHKDKMKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWDKDWSAIVSGKNLAYQALAQYHQSEVCGEARQIGEQLSRLAESLKLFDTAQKYLPRDITGIWDIYPSVSKAHAAAKKDNDFIYHEKVSDFRTLPTLPKAVLAKPTPMQTPMTPSFRDMFAVLVPVQVHNAMQSYDARKAELVNMETVRMREATQLMNGVLASLNLPAALDDVTSTETLPESLKLKSAKLKQNGGSSEIMRLFSELPTLYQRNEDILTETSRILNEEKESDDTMRKQLGTKWTRMSSEQLTGPLVTEIGKYRGILHTASNADKMVKEKFESHRQGIELLSKNESELRSSIPGQTAHATGETDTVRQLRQFMSQWNEVTTDRELLEKELKNTNCDIANDFLKAMAENQLINEEHISKEKIAQIFGDLKRRVQSSLDTQETLMNQIQAANNTFTGEKTGSSTGAERERILKMLAQASDAYVELKANLEEGTKFYNDLTPILVRLQQKVSDFAFARQTEKEDLMRQLQLSIVSGQAAKAVVDGVNSLVSSYLTGGTNAAQSPANAPPRPPPPRPAAPSVESPIPPPRTQQSMQATPGAPPQYNPYQQQQQPQMQQFQQHPGYYQQPMPYGQPQPMFQPQYQPTFAAPYPTFPGAFPSYQQQWPQQQQQGGFPPNPQFGQQNQQQGGGGGANPFQ
Protein: Cysteinyl leukotriene receptor 2 (CysLTR2) (RSBPT32) (Q924T9)
Organism: Rattus norvegicus (Rat)
Function: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Cysteinyl leukotriene receptor 1
- Guanine nucleotide-binding protein subunit alpha-11
- Leukotriene C4 synthase
- Guanine nucleotide-binding protein G
- Neurotensin/neuromedin N
Sequence:
MGVTGTPSYYSDKNCTIENFKRDFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYNFRGSDWIFGDWACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVFIMASSGLLLKHGQEKKNNTTLCFELNLQKFKNLVILNYIALGVGFLLPFFILTICYLLIIRVLLKVEIPESGPRDAQRKALTTIVIAMIIFLLCFLPYHALRTIHLVTWDADSCMDELHKATVITLTLAAANSCFNPFLYYFAGENFKARLRAIFSKDHL
Protein: Amino acid transporter (A0A3Q1MV72)
Organism: Bos taurus (Bovine)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
Interaction partners:
Sequence:
MPALRGQRIPGDESMVSANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMCAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK
Protein: Vimentin (P02543)
Organism: Sus scrofa (Pig)
Function: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P08670}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P08670}. Nucleus matrix {ECO:0000250|UniProtKB:P31000}. Cell membrane {ECO:0000250|UniProtKB:P20152}.
Interaction partners:
- Desmin
- Uncharacterized protein.
- Caspase-3
- Caspase-6
- Caspase-3
- Caspase-8
Sequence:
MSTRTVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYTSSPGGVYATRSSAVRLRSSVPGVRLLQDAVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEETLQREEAESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHDEEIQELQAQIQEQHVQIDMDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESNEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLESLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
Protein: Adhesion G protein-coupled receptor F4 (G-protein coupled receptor 115) (Q9D2L6)
Organism: Mus musculus (Mouse)
Function: Orphan receptor.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MKPWIAMVCCLVFFLTTECSHSKPKTHRKDEDKFQISLQKHEFRPRQGKCDGLCSSSSSCNQSCPWNFRGEIVFTCNQNKWQKTIETCTSLSVDTLFQRIHPAASLSLASSSVFPMSLIGNAAPVHIGNVFQGIQKYCPEDYVCIVDAVKSSAVTSGNIAFIVELLKNISSNLQTSGIHDNVNWKKMKNYGKVANHILGPTAISNWAFIANKNASSDLLESVNSFAKKLQIQGKSESIVDELFIQTKGSRISHSSSEHSLSLSVPRYNATEDVLVVIEIPRQALQELSFNASQAIVVAFPTLGAILKEVHRPNTSLQKPIDDLILSLVLPEGLNEIILTFDKINKSQSTSSQCVSWDPATGQWDESPCTVMSDINSTVKCRCRHTKAVTSFSILMSSKPVKNTILNHITFIGLSISIFSLVLCLVIEAIVWSRVVVTEISYMRHVCIVNIAVSLLTANVWFIIGSNFSANVQEDHKWCVAVTFLCHFFFLSLFFWMLFKALLIVYGILVVFRRMMKSRMMAIGFAIGYGCPLVIAVITVTVTEPGEGYTRKDACWLNWNQTKALFAFAIPALAIVAVNLLVVLAVAINTQRPLIGSSKSQDMAIVFRISKNVAILTPLLGLTWGFGLTTLLEGVHLVFHIIFALLNAFQGFFILLFGTIMDHKIRDALRMRVSSLKGKSRAAEKVSLSPANGSRILNR
Protein: Kinesin, putative (Q38CF1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLHKPCVQVVMRFRPNPGVASPFYSTDDTGAPWLTYDERTVRVVERDPPMDRKRVEPNGGPCGDSNDPPVSKALVPAPVTSYTFDAVLSDTSTQRDVHKCVGEPVIGNVLKGYNATIFSYGQTGSGKTYTMLGPYGGLADAFFEDSPFYGERGLVPRVVEELFNRLNTMKSEEYTWRVKTQMFEIYRENIVDLLIEGDQQPQTEYRIREGKNSQGSFCMYVDSLKEVECRTAADFMDILQRGVASRHTRETGTNDRSSRSHCLLCLFVELKHNEDYSMWTESRLNFVDLAGSERVATSQAEGETLKETQYINLSLSLLGNVIHRLAGGNTGHIPYRDTKLTRVLKDSLGGNSLTTLLCHGTTEAATKSQTINTLRFAQKALRIKTRAVVNKPSKTTIKQQQQEFYKEHTKQLEKQIRVLQEIIRSRENTEGENSMCAKCESMSATIASLTKEIERLQKELIAREEQLQQTQETGDYYKKNCETLENELAKLTEEQEANDARHIEAYTILEEESENLRAEIEALQKQLAEKPHKDASNSEALSNKNNTRKNNYNDYKNRATMTDRRTHSNCCTMTDPVTIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTISTNRATMTDCRTHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTISTNRATMTDRRTHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTVSTNCATMTDLRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTISTNRATMTDLRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTVSTNCATMTDLRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDLRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTVSTNCATMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTVSTNCATMTEVCRQSNSLDRRVSCVSGTAENVSLSGETFCRNTSVNTRECSYIARNTIFASSVVSSFVPVIGEGQFEWWCLDDVYAHALLFSYCNPRDVGINIGLFDDCDDKVLLQSLGVVHRTLGSIRADYDGSVVSVIRRFLVQQRGALAGDGALEGCVPCEALFEVLISAKNALLVEPMVSDSSTVKGEDRVCHGDGEGALDSCVYAHLQVAMTAVFSIARERGGYLSDIFASVKVQKALEAMRQFFTSSNLFSSGSSSVSSTSEANGDSSSFLEDMLRETEVPRFVLGGALQRAAALLKDDVVTKLQRRRLCGGLSLEEALLACYLAEERITALTEIENLREEMVQPVTREALDLIDGAVRAFLKSEESEDFSAEATNHMKSSSFTTALAFLFTYVAAQTATETVGLPQDSTEHVRDALNVVAQTLLRRSVSQTSRFDVAQSNTAIDPESMQQSLRIIMDYAESQGYYPVTCDTSEAGSRSNHHCQYSQQTRRKDTPDIDVTKREALMEKMDSPRTTPRSSPHPRLSSPQEQRPQTSVVVVSQPNVTSHHINNLVHRGRMTNPVAIVMPDVMEDMQRRLTKELINCGTMTDGTISTNRATMTDLRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDGTISTNRATMTDLRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDMQRRLTKELINCGTMTDIRSHSNCCTMTDPVAIVMPDVMEDVQRRPSNRLDASTSLKVSKNNGDVAVYEAVRFGDEKVVVDSCSVASVSDSFPRDLSSEVGKLQLRVLDLGKEVYMLQKELMAREEQLQKTQERADYYKKNCETLENELAKLTEEQERNDARRTEAYTILEEESENLRAEIEALQKQLAEKPHKDASNSEALSNKNNTRKTDSDHAVDGKENLGLHHVSSVRSLVHLRENKAREHLRSRSLSNGREPPGGVLPTELRTWPQTAQQSAPAACTHEKGVERKLSEELDESDVVNHLTAQATPEMLNLKPELFVKNPASFDRLVSYLTRLVERAEREPGALSCEERHLSEVLKVFSTFYCGYRSIESGTGTCPIVDGNLRSRGGSSHSLRPRAKGMWSPESLRVSPDVGRNVDAVKEDQNGKHLGPVPSASTTFRTGRSERCTSSVRGVALVGGLLASRRRSSTAPSPTEGPRVPLQREEIEDLEGMSELVSSIEDMQSQLAYFNFSNEPELRESIKQLQQHLEELRAVLESQMSTTKMSRSPSYISSFRGSCFSQGNQQGQGVQEGKPPLKAESNGCQPATDSACDTNYSNGGQTGYLAVCNAVNTCCGGRGAFHRGSNRCSHWVPLRMHRANHDENVGLAMNEPGGSIPQGRSNAFDDGSQRKCMAPNRRNQSAVMRRLLDSMRFDLDSYVYTAAEQNAASAALLEESSSLKEREADMWLRLNQTEFCEMARIEMRLKRDDLRELQHEIHRMHLLHDKELVERKRRLLIYSYRKLLDFAKRMSDILKAREFCTGTLESQRLLLLDETSDFTKDVEKYIEVL
Protein: Filamin C, gamma a (actin-binding protein 280) (Filamin-C isoform X1) (A0A0R4IUS4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSNYTHLDDLPPQYYQGTDLGEEEEEEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKGVTDLQKDLGDGLKLISLLEVLSQKKMYRKHHVRPNFRQMKLENVSVALEFLDRERIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEEVKKLTPKQRLLGWIQNKVPELPINNFNKDWRDGKALGALVDNCAPGLCPDWQTWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPVKPKQLYPKKAKAYGPGIEPQGNMVLKPAVFTVETLEAGLGEVIVYVEDPEGHTEEAKVVANNDKKRTFSVTYVPKVEGRHKVKVLFAGQDIDKSPFMVNVAKALGDPNKVQARGPGLEPEGNVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQPIPSSPFKVNISEASNANACRATGRGLQPKGVRVKEVADFTVFTKGAGTGELKVSVKGPGGVEVPVKVCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEVSKEAGTQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKAFGPGLEPTGVTVNKSTQFTVDAREAGKGGLKIYAQDAEGCVIDIQITDKGDGTFVCVYVPTKPVKHTIIITWGEVNIPKSPFRVLVGEGCHPDKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGPGRYTIMVVFADQEIPSSPFKVKVDPSHDAGKVRAEGPGINKTGVQVEIPTHFTIFTKGAGKAKPEVHFKTAAKGNAVKDFEIIDNHDYSYTVKYTALHQGEMAIVVTHGGDPIPKSPFKITVAPSLDLGKVKVQGLNEKVEVGKDQEFIVNTKGAGGQGKVNVSITSPSGRPIPCKLESDKTKEATCVKYIPPEEGHYKVDITYDGNPVPESPFSVEGLMPADPSKVRAYGPGLKGGIVGQPAKFSIDTKGAGAGGLGLTLEGPCEAKIECQDNGDGTCSVVYLPTEAGDYNINILYGEAHIPGSPFKAVVKPALDAGKVTASGPGLERAKAGEVASFTVDCSRAGEAELTIEIVSDSGAQAEVCIQNNKDGTFSVTYTPLFHGVHTITIKYGGQQVPKSPIHVKVEPSVDTSGIKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGCDPTRVRAYGPGLEGGIVNKPNCFTVETRGAGTAGLGLTIEGASEAKMLCKDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQVKDVVDVSKVKCSGPGLANKVTAHVPQTFTVDCSKAGVAPLEVQLYGPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASKVRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHDNRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQAFPTGDASKCLLTVSIGGHGVAESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMATDQPVAPRDDTKPMFQPLNLVIPFTVQQGELSGEVRMPSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPLQFYVDVTNSGMVTAYGPGLCHGTVNKPASFTVVTKNAGQGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGDDSLRRSQLNVGTAADVSLKITETDLSYLTASIKAPSGKEEPCLLKRLPNRHIGLSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVGPSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDINCDDVEDGTCKVTYCPTEPGNYIINIKFADKHIPGSPFTVKVTGEGRMKQSITRKRQAASIASVGSTCDLNLKIPGNWFQMLSAQERLTRTFTRSSHTYTRTERTEISKTHGGETKREVHVEESTQVGGGGGDPFRDVFESFLGRDRLGSFGTIRQEGETGIQGMTAQVTSPGGNLADAEIVDSGNSTYRVRFVPTEMGSHTVNVKYRGEHVPGSPFQFTVGPLGEGGFHKVRAGGTGLERAVAKVPAEFSIWTREAGAGGLSIAVEGPSKAEINFEDRKDGSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIVPVATLSDDARRLTVTSLQEKDLKVNQEASFAVQRNGARGVIDAKVHAPSGVVEECYVTELDSDKNAIRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGLEGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEGYKISYTPMAPGNYLICIKYGGPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKNSFSVDCSKAGTNMLMVGVHGPRTPCEDVTVKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPFHVSAP
Protein: Shikimate kinase 1, chloroplastic (OsSK1) (EC 2.7.1.71) (Q5NTH4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Subcellular location: Plastid, chloroplast {ECO:0000305|PubMed:15891897}.
Interaction partners:
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Os12g0534000 protein
- Shikimate kinase 3, chloroplastic
- Os01g0375200 protein.
- Os01g0375500 protein
- Chorismate synthase
- Chorismate mutase
- Os01g0375350 protein
- chorismate mutase
- Chorismate mutase
Sequence:
MEAGVGLALQSRAAGFGGSDRRRSALYGGEGRARIGSLRVAEPAVAKAAVWARGSKPVAPLRAKKSSGGHETLHNSVDEALLLKRKSEEVLFYLNGRCIYLVGMMGSGKSTVGKIMSEVLGYSFFDSDKLVEQAVGMPSVAQIFKVHSEAFFRDNESSVLRDLSSMKRLVVATGGGAVIRPVNWKYMKKGLSVWLDVPLDALARRIAKVGTASRPLLDQPSGDPYTMAFSKLSMLAEQRGDAYANADVRVSLEEIASKQGHDDVSKLTPTDIAIESFHKIENFVIEHTVDNPVGDSQADSRAQRIQTL
Protein: Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8) (P98187)
Organism: Homo sapiens (Human)
Function: A cytochrome P450 monooxygenase involved in the metabolism of endogenous polyunsaturated fatty acids (PUFAs) and their oxygenated derivatives (oxylipins). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds, with preference for omega-1 and omega-2 positions. Hydroxylates (5Z,8Z,11Z,14Z)-eicosatetraenoic acid (arachidonate) predominantly at omega-2 position to form (18R)-hydroxyeicosatetraenoic acid (18R-HETE). Exhibits omega-1 hydroxylase activity toward prostaglandin (PG) H1, PGH2 and PGI2. Catalyzes the epoxidation of double bonds of PUFAs, including docosahexaenoic and docosapentaenoic acids. Shows little activity against PGD2, PGE1, PGE2, PGF2alpha, and leukotriene B4.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9HBI6}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9HBI6}. Microsome membrane {ECO:0000250|UniProtKB:Q9HBI6}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9HBI6}.
Interaction partners:
- Cytochrome P450 2J2))
- Cytochrome P450 2U1
- Prostaglandin G/H synthase 2
- Cytochrome P450 2C9
- Cytochrome P450 2C8
- Cytochrome P450 2B6
- Polyunsaturated fatty acid lipoxygenase ALOX15B
- Cytochrome P450 4A22
- Cytochrome P450 4A11
- Polyunsaturated fatty acid lipoxygenase ALOX12
Sequence:
MSLLSLSWLGLRPVAASPWLLLLVVGASWLLARILAWTYAFYHNGRRLRCFPQPRKQNWFLGHLGLVTPTEEGLRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVEPLG
Protein: At1g13730 (Expressed protein) (F21F23.16 protein) (Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein) (Q9LMX6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 24
- Carbohydrate-binding-like fold
- Nucleolar GTP-binding protein 1
- Guanylate-binding family protein
- NTF2-like protein
- Nuclear transport factor 2 family protein
- protein-synthesizing GTPase
- Nuclear transport factor 2
- Universal stress protein PHOS32
Sequence:
MALESNAPVVDPNTIGNSFVEKYYNLLYKSPSQVHQFYLDDSVLGRPGSDGEMVSVKSLKAINEQIMSFDYEISKIQILTADSQASYMNGVVTLVTGLLTVKEGQRMRFSQSFFLVPLNGSYFVLNDVFRYVADEIVEPEANKKEVEEVIPQVVQPTEQVDEVAEPVTIPTQQPEAKQTTENTVKKPERAVANGHPKTQEDNVVNDKSNGVDAPKKSFAHIVQDLAQNGATFNAKASPAKPKSKPVTKPSAARESKAPAPVSEHSSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIQVRSYRLKGNCFGFVTFASAEAVKLVLQAHKESAIRIGNRRVSIEEKRGNNDNGRPAMRNGGYRNDNGYRNDGYRPRGNGSNGGRGYGRNGSERRGESRNGEAHNGDGKVHQNGTVEASR
Protein: Chaperone protein DnaJ 1 (P9WNV9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01152}.
Interaction partners:
- Chaperone protein DnaK
- Protein GrpE
- Probable heat shock protein transcriptional repressor HspR
- Chaperonin GroEL 2
- Chaperone protein ClpB
- Chaperonin GroEL 1
- Chaperone protein HtpG
- Conserved hypothetical proline rich protein
- Conserved hypothetical proline and threonine rich protein
- Hypothetical alanine and valine rich protein
Sequence:
MAQREWVEKDFYQELGVSSDASPEEIKRAYRKLARDLHPDANPGNPAAGERFKAVSEAHNVLSDPAKRKEYDETRRLFAGGGFGGRRFDSGFGGGFGGFGVGGDGAEFNLNDLFDAASRTGGTTIGDLFGGLFGRGGSARPSRPRRGNDLETETELDFVEAAKGVAMPLRLTSPAPCTNCHGSGARPGTSPKVCPTCNGSGVINRNQGAFGFSEPCTDCRGSGSIIEHPCEECKGTGVTTRTRTINVRIPPGVEDGQRIRLAGQGEAGLRGAPSGDLYVTVHVRPDKIFGRDGDDLTVTVPVSFTELALGSTLSVPTLDGTVGVRVPKGTADGRILRVRGRGVPKRSGGSGDLLVTVKVAVPPNLAGAAQEALEAYAAAERSSGFNPRAGWAGNR