wanglab/gogpt-training-data huggingface dataset:
Protein: Upstream binding transcription factor (E9PKP7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSPRRMMKRMRMTRTRMKKRKMMRMGTPLKMAATPLSPAARTRARMGMRMKRMTRTKTTTRMTMRMKIMSPRAAAPAPPPQGTPQTLTPTEAQPHPRAARESPGAPLPN
Protein: Protein ENHANCER OF LHP1 1 (F4JF14)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Participates in maintaining the H3K27me3 mark at target genes by interacting with LHP1-PRC2 complexes during replication, thus contributing to H3K27me3 inheritance.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:28428341}.
Interaction partners:
- DNA replication licensing factor MCM5
- DNA polymerase alpha catalytic subunit
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM3
- Cell division cycle 45
- DNA replication licensing factor MCM7
- DNA polymerase epsilon subunit B
- Zinc knuckle
- DNA replication ATP-dependent helicase/nuclease JHS1
- DNA replication complex GINS protein SLD5
Sequence:
MKSRSLKLREAHKVGGSAAFCSILWDHKAEHFVTSSSSDPSISVHDGLSTSTLPPTILRHHQDGVTSLALSNDSTLLASGSIDHCVKLYKFPSGEFQTNITRFTLPIRVLAFNGSGSLLAAAGDDEGIKLINTFDGSIVRVLKGHKGPVTGLDFHPNGELLASIDTTGTVLCWELQNGVVSFTLKGVAPDTGFNTSIVNIPRWSPDGRTLAVPGLRNDVVMYDRFTGEKLFALRGDHLEAICYLTWAPNGKYIATSGLDKQVLLWDVDKKQDIDRHKFEERICCMSWKPNGNALSVIDAKGRYGVWESLVPSSMLSPTVGVPDIVPKKRNEILDFDDEVEEEIYRASESLDDAMGDSDDGESHHTSRKRLRKKTLIDEDVDDAYEELNDGSSLPSASEYRKKSHRGHREKQGARSGAFKGISASTKYKMQSSFQPGATPPEPGKRTFLCYNMLGCITTIEHEGNSRIETDFHDTGRGPRVSSMIDIYGFTMASINETGCVFANPCKGEKNMSVLMYRPFRSWASNSEWTMRFEGEEVKVVANGSGWVAAVTSLNLLRVFSEGGLQKHILSLDGPVVTAVGCKDHLAVVTHVSDCLPSNEQVMEFRVFNISKMTQELKGRVALTPGSRLTWIGFSEEGSLSSYDSEGVLRVFTSQYGGSWIPVFSTSKEKKQEENYWVVGLNTSSLYCIACKYAEMFPQVTPKPILTILDLSLPLASSDLGAASLENELILKQLRLYETQRKVDDMALVGVDTTALEDEAFDLEVSQDKCILRLISSCCSSDSFARASELMELLTLEKSMRAAITLVTKLKLPFLAEKFSSILEERLLEEASEAAVTNPALNPNGEVVTRVESKVQNPPASIQTSENTEAVMKSSATKLSAPTLLKKSKVSEGLKLGKEQTKKDKSDDAKIKEIKKLNLKNPVNNVNKEDKGQEKEVNQGEARRSSNPFLKSTV
Protein: Phosphoenolpyruvate carboxylase (PEPC) (PEPCase) (EC 4.1.1.31) (Q43299)
Organism: Amaranthus hypochondriacus (Prince-of-Wales feather) (Amaranthus hybridus var. hypochondriacus)
Function: Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Subcellular location: Cytoplasm.
Interaction partners:
Sequence:
MASGKVEKMASIDAQLRLLAPKKVSEDDKLVEYDALLLDRFLDILESLHGSGIRETVQELYEHAAEYERTHDTKKLEELGNLITSLDAGDSIVIAKSFSQMLNLANLAEEVQLAYRRRIKKTKKGDFADESSAITESDFEETLRRLVDLKKSPEEIFATLKNQTVDLVLTAHPTQSVRRSLLQKHGRIRDCLSQLYAKDISPDDKQELDEALQRAIQAAFRTDEIRRVQPTPQDEMRMGMSYFHETIWKGVPKFLRRVDTALKNIGINERVPYNVPLIQFSSWMGGDRDGNPRVTPEVTRDVVLLARMMAANMYFTQITDLMFELSMWRCNDEVRARAQELHSQSKSDAKHYIEFWKQIPLSEPYRVILGDVRDKLYNTREHAHKLLANGSSDVPEESTFTHIDQFLEPLELCYKSLCASGDQPIADGSLLDFMRQVSTFGLSLVKLDIRQESDRHTEVMDAITTHLGIGSYRSWSEEKRQEWLLSELRGKRPLFGSDLPMSYEVADAIGTFRVLAELPNDSFGAYIISMATAPSDVLAVELLQRECGIKKPLRVVPLFEKLADLQSAAASMTRLFSIDWYKNRINGTQEVMIGYSDSGKDAGRLSAAWQLYKVQEQLIQVAKEYGVKLTMFHGRGGTVGRGGGPTHLALLSQPPDTIHGSLRVTIQGEVIEQSFGEEHLCFRTLERYTAATLEHGIDPPTSPKPEWRALMDEMAVITTKEYRSVVLQEPRFVEYFRSATPELEYGRMNIGSRPAKRKPGGGIETLRAIPWIFSWTQTRFHLPVWLGCGAAFKHVIEKDIKNLAMLKDMYNQWSFFRVTIDLLEMVFAKGDPGIAALYDKLLVKDELKPFGENLRKSYLEAQKFLLEIAGHKDPLDADPYLKQILRLRDPYTTTLNVFQVYTLKRIRDPSFHVTVRPHLSKEMDANSLAADLVKLNPTSEYPPGLEDTLILTMKGIAAGMQNTG
Protein: Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] (P80067)
Organism: Rattus norvegicus (Rat)
Function: Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase (By similarity).
Subcellular location: Lysosome {ECO:0000269|PubMed:1740150}.
Interaction partners:
- Apoptosis regulator Bcl-2
- BH3-interacting domain death agonist
- Bcl-2-like protein 1
- Legumain
- Cathepsin D
- Cathepsin G
Sequence:
MGPWTHSLRAALLLVLLGVCTVSSDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPIPKL
Protein: RRM domain-containing protein (A0A0B4LGA2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small nuclear ribonucleoprotein Sm D3
- Probable small nuclear ribonucleoprotein G
- U1-C C2H2-type zinc finger domain-containing protein
- Probable small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein F
- LD45152p
- Splicing factor 3B subunit 6
- PHD finger-like domain-containing protein 5A
- Splicing factor 3B subunit 1
- Uncharacterized protein, isoform A
Sequence:
MSALSSKLLMKRMPCSLDELAQLIRECKLILPRSLNTYGRKRVLLEYADPEEAAKALEQLQELSESLDKPLCISVFGPRPSSGAASASSKSTQTSGAGNGGAVSGFPDIDKYVRRLYACNNQCDFTQPPPPYLSYSYPPINGEILARIGQSLQTNSHFYNQVLHLMNRMNLEPPFEKRPDGLMAQMHRQHVGTQTELIPSESESELESDDGEQKLAKRQRLLLAPASEEARAKTLKRARQMLQQAAQLASHTKPKLTVQKPSFDAPKIEMKLPETLVPPPIHPERRESISKPETGASTSKAVRRLSTSALEALPVYKNYKTGDPSNKLYIKNLAKSVDEQQLRELYAKYTAASKLDIKVMHQGRMKGQAFVTFLDANNPEIIAQALNETNGLLWHDKPMIVCYGKQQ
Protein: Cancer/testis antigen family 45 member A3 (Cancer/testis antigen 45-3) (Cancer/testis antigen 45-4) (Cancer/testis antigen 45A3) (Cancer/testis antigen 45A4) (Cancer/testis antigen family 45 member A4) (Q8NHU0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:31429579}.
Interaction partners:
Sequence:
MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI
Protein: Transcription factor GTE9 (BROMODOMAIN AND EXTRATERMINAL DOMAIN PROTEIN 9) (AtBET9) (Bromodomain-containing protein GTE9) (Protein GLOBAL TRANSCRIPTION FACTOR GROUP E9) (Q93YS6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- BTB/POZ and TAZ domain-containing protein 2
- SCP1-like small phosphatase 4
- At5g11860
- U-box domain-containing protein 3
- CLK4-associating serine/arginine-rich protein
- Protein SHOOT GRAVITROPISM 6
- SWR1 complex subunit 2
- Transcription factor Pur-alpha 1
- At5g17540
Sequence:
MTERNGGFPGDYCFEAPGGDYDEGSDSPRVSEGSNCSKRKVGETFGVSKMVLPLSGLSSSDRKELIRRLRQELEQIRVFQKNFELSRTVALTSSSASGLTRVKSFGMSRCSTGPGKTVNPISAASKPTPVTTAVMLLMKQCEALLKRLMSHQYGWVFNTPVDVVKLNILDYFNVIEHPMDLGTVKNKLTSGTYSCPSEFAADVRLTFSNAMTYNPPGNDVYVMADTLRKFFEVRWKTLEKKLSGTKVHTEPSNLDAHKEKHIVIPVPMAKKRKTTAVDCENVVDPAKRVMTDEDRLKLGKDLESLTEFPAQLINFLRDHNSNEGGIGDDEIEIDINDLSDHALFQLRDLLDEHLREIQNKKSSVEPCEIELLHGSVPGNSSMQHCDGSELDDEVVDIGENEHPTSSISPVTIEKDLVLGNSNGNSLGSVSGDPKMSSLPRASKGLGTIDLEPMLDGATSASPTRGSSVGGLDQLESASPEKISSVEADCQQDGNSAQNEKQLPPEKSYRAAILKNRFADIILKAREKPLNQNDTRDPEKLQREREELELQKKKEKARLQAEAKAAEEARRKAEAQAAAEAAAEAKRKLELEREAARQALMEMEQSVELNENAKFLEDLELLKTVDTDHLTNTIEEEDGPDVGLRSFSFGGSNPLEQLGLFMKQDEDEEEADPLTSPAPEIDIEEGEID
Protein: Holliday junction branch migration complex subunit RuvB (EC 3.6.4.-) (Q51426)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00016}.
Interaction partners:
- Holliday junction branch migration complex subunit RuvA
- Crossover junction endodeoxyribonuclease RuvC
- ATP-dependent DNA helicase RecG
- DNA repair protein RecN
- RecBCD enzyme subunit RecB
- S-adenosylmethionine:tRNA ribosyltransferase-isomerase
- DNA helicase II
- DNA polymerase I
- UvrABC system protein A
- DNA repair protein RecO
Sequence:
MIEPDRLISAVSGRERDEQLDRAIRPLKLADYIGQPSVREQMELFIHAARGRQEALDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSGPVLERPGDLAALLTNLEAGDVLFVDEIHRLSPIVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYNVEDLATIVSRSAGILGLEIEPQGAAEIAKRARGTPRIANRLLRRVRDFAEVRGQGDITRVIADKALNLLDVDERGFDHLDRRLLLTMIDKFDGGPVGIDNLAAALSEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPKRLGPGVTTDLFTSEDGN
Protein: Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH (EC 4.1.2.28) (P39359)
Organism: Escherichia coli (strain K12)
Function: Functions as a 2-dehydro-3-deoxy-D-pentonate aldolase.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- D-xylonate dehydratase YjhG
- D-xylonate dehydratase YagF
- Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE
- Uncharacterized HTH-type transcriptional regulator YjhI
- 4-hydroxy-tetrahydrodipicolinate reductase
- Lactaldehyde reductase
- Lactaldehyde dehydrogenase
Sequence:
MKKFSGIIPPVSSTFHRDGTLDKKAMREVADFLINKGVDGLFYLGTGGEFSQMNTAQRMALAEEAVTIVDGRVPVLIGVGSPSTDEAVKLAQHAQAYGADGIVAINPYYWKVAPRNLDDYYQQIARSVTLPVILYNFPDLTGQDLTPETVTRLALQNENIVGIKDTIDSVGHLRTMINTVKSVRPSFSVFCGYDDHLLNTMLLGGDGAITASANFAPELSVGIYRAWREGDLATAATLNKKLLQLPAIYALETPFVSLIKYSMQCVGLPVETYCLPPILEASEEAKDKVHVLLTAQGILPV
Protein: Myosin binding subunit, isoform O (M9NEB2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Serine/threonine-protein phosphatase beta isoform
- Serine/threonine-protein phosphatase alpha-2 isoform
- Myosin regulatory light chain sqh
- Rho-associated protein kinase
- Ras-like GTP-binding protein Rho1
- non-specific serine/threonine protein kinase
- Myosin heavy chain, non-muscle
- Serine/threonine-protein kinase polo
- Myosin-2 essential light chain
- Serine/threonine-protein phosphatase alpha-1 isoform
Sequence:
MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKFYQKYNELRARIKANSCPILPANANANAAAANKSNNNNNLSSNNYHNNNNNNNKSDLLLGYAAGTTTTTSTPTTTTTTTSSTFNNTHSNTNNTSTTQQQPAAAAAASAANQLYSVQRSASLKDNSMYYRKPTVTIATSTAATAINSPSTTVQTPPIRSQVTAKIAEKSNNGSSSTASVSDAESSKPPPKQSASNMIKNFFKSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGNETSSASSTSAPTPSILGSNEQQDELQPPPPPTTPPPAVIPTTTTATDETEIEEVVSSPPAGQSQNDTTASFTLSAPVRRSLSTEGEADANSDPEGDQDQTVVSASYTIMPRRERLPESSENVESIRSPQKTEPVAKSSSEDKSEEPPHARPTDLPLIPAPAAPSTEAIKSSSAATTPAALESPVRLRDKRGLSGSQESETKSDTASPVSSHPDFNARDSLLSLYARRTTDSSAGGGGVGGGAGVGAGGASGAATSSSTSAAERRPSWRLKFDAGSKFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSNDKTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFANATTKNSLSELEKRERRAMERKLSELEEELKQLDAYKSDNHRLKEENAALIRVISKLSK
Protein: Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin) (O35166)
Organism: Mus musculus (Mouse)
Function: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:O35165}; Single-pass type IV membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:O35165}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O35165}. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. {ECO:0000250|UniProtKB:O35165}.
Interaction partners:
- Syntaxin-5
- Vesicle-trafficking protein SEC22b
- BET1 homolog
- Golgi SNAP receptor complex member 1
- Synaptobrevin homolog YKT6
- Sec1 family domain-containing protein 1
- BET1-like protein
- General vesicular transport factor p115
- Syntaxin-6
- Vesicle-trafficking protein SEC22a
Sequence:
MEPLYQQTNKQVQEIQSHMGRLERADKQSVHLVENEIQASIEQIFSHLERLEILSSKEPLNRRQNAKLRVDQLKYDVQHLQTALRNFQHRRQVREQQERQRDELLSRTFTTNDSDTTIPMDESLQFNSSLHNIHHGMDDLIGGGHSILEGLRAQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCAVMFLVVQYLT
Protein: HTH-type transcriptional activator RhaS (L-rhamnose operon regulatory protein RhaS) (E0SJ56)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01534}.
Interaction partners:
- HTH-type transcriptional activator RhaR
Sequence:
MTQLHGDEFFASQAATVAVEPRMPQCAFPEHYHDFWEIVLVEQGAGVHVFNDQPFALCSGAVFFVRDNDRHLFEQVEELHLTNVLYRSPRGFRFLSDIAPFLPYGANGEWLGQWQVNVAAQQQVKQLILQLAALARRDQPEDIAASESLFLQILVLLRQKRFQTQGDGSERQGIQALLGWLQHNFCEEVDWDTLADRFSLSLRTLHRQLKQHTGMTPQRYLNRLRLLEARRRLQHSDDSITTIAHDCGFSDSNHFSTQFRKAFALAPKTLRHQAQYED
Protein: ADNP homeobox 2b (Activity-dependent neuroprotector homeobox protein 2b isoform X1) (A3KQW9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MYQFPVKGLEKIRRTRRKVKNILGEFGLEACLNLGQELQEYYPGDNIFDATDWCNLSDGFDGRWRKKWEYRTQGLCCTLCNFSTRSWHTYKTHVQRYHDEEEHMCKLAACASCPFIAHPRLVCKHLKLFHNEDTKSETSAAPQLPPRAVNGTTFQCRRCHIQDTLLYSVKKHVLLYHYTSTLNKYAGQRTEQELVALGDRSQKFYCKKCYISAESSEHLLYHLLTSDKHKELDVHIRSLIFETDNKKQFPALAPKAQGPSPVMMMKDQPAATATLAAGGITGVENGGSAVIATPGTSQAFLPTQASALVQLASAEAKGLLRPGVPMGFQNTQMPRPALPPPPNSIPPNQMPVRVGLPNQAQLQPVSRQIVLPPGVRLNVPGVRPPTPQSFSANPRLPLNQPPSGGTMLTSQSLLSHLIPTGNKVDGLPTYTLAPLQVLSVQANNSQGVSKPQLPPSQNNPAAQQNKQSSGLSTPKQTKKWITCPICNELFPSDIYESHPEVHKEAAKLPKVGLAARAPFLKKMPDKTVKCLTCKILISEKGVFEHLLHGMNCLFCSGLFYSIKQLVDHIQIEHNVSRKSNCDFMRREYRLYTDDSGNLLFPYFDIRTTAPKLIMGEKELNLALVTSSLDLIFVKMLPNNPQGVNQQYTPCKMPTPKPDSTECPFCSEKLLNKECYHMHLKEKHFIVPTLHAILKTPSYRCLYCGGVYTGKTTTKAIIVHLAKCRSAPKSVRESDKLTLGLAVTPKANRAHGSYPAHPRQITGPTPTSAQASVPSTQPPESEAEMQSKMRLEIAFREAMEANRKEREERLARKRKLERDRLAGLTLPSPDIVVDPSVKLALDPAGMELRTFEDRREFVNKYFNTQPYPLKKEIIALSARLLLNKTDVACQISSKRTRCMKNIQKMKAVVLLGFNMTEVMKLKHDLLIPEIEPEKVATMADTDMEVDQE
Protein: Autophagy-related protein 101 (Q9BSB4)
Organism: Homo sapiens (Human)
Function: Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19597335}. Preautophagosomal structure {ECO:0000269|PubMed:19597335}. Note=Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. {ECO:0000269|PubMed:19597335}.
Interaction partners:
- Autophagy-related protein 13
- RB1-inducible coiled-coil protein 1
- Serine/threonine-protein kinase ULK1
- Serine/threonine-protein kinase ULK2
- Beclin 1-associated autophagy-related key regulator
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Beclin-1
- Phosphoinositide 3-kinase regulatory subunit 4
- Guanine nucleotide exchange factor C9orf72
- Serine/threonine-protein kinase mTOR
Sequence:
MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITDALGTSVTTTMRRLIKDTLAL
Protein: Host cell factor (dHcf) [Cleaved into: HCF N-terminal chain; HCF C-terminal chain] (Q9V4C8)
Organism: Drosophila melanogaster (Fruit fly)
Function: May be involved in control of the cell cycle.
Subcellular location: Nucleus {ECO:0000269|PubMed:12609738, ECO:0000269|PubMed:18327268, ECO:0000269|PubMed:21694722}.
Interaction partners:
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- Protein will die slowly
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Transcriptional adapter 2A
- Histone-lysine N-methyltransferase SETD1
- Ada2a-containing complex component 1
- Ubiquitin carboxyl-terminal hydrolase calypso
- Retinoblastoma-binding protein 5 homolog
- Transcriptional adaptor 3, isoform C
- Ada2a-containing complex component 2
Sequence:
MEGSDFVDPAFSSGERISASDLNSEHIIQAENHSFANRISMDMDVPDGHQLDSNLTGFRWKRVLNPTGPQPRPRHGHRAINIKELMVVFGGGNEGIVDELHVYNTVTNQWYVPVLKGDVPNGCAAYGFVVEGTRMFVFGGMIEYGKYSNELYELQATKWEWRKMYPESPDSGLSPCPRLGHSFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILDTRGVHSHNGKWIVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGMSGCRLGDLWLLETDSMTWSKPKTSGEAPLPRSLHSSTMIGNKMYVFGGWVPLVINDSKSTTEREWKCTNTLAVLDLETMTWENVTLDTVEENVPRARAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHALELSWTATTFAAAYVLQIQKIEQPLNTSSKLLSNNIVQQGTPTSAETSGINISANRSGSALGLGVEATSTVLKLEKESLQLSGCQPETNVQPSVNDLLQSMSQPSSPASRADKDPLSSGGGTTFNLSTSVASVHPQISVISSTAAVTGNDTASPSGAINSILQKFRPVVTAVRTSTTTAVSIATSTSDPLSVRVPSTMSANVVLSSSSSTLRIVPSVTASHSLRIASSQASGNNCRSSSAINILKTALPNVAVQSQPTSSTTTSIGGKQYFIQKPLTLAPNVQLQFVKTSGGMTVQTLPKVNFTASKGTPPHGISIANPHLASGITQIQGSTVPGSQIQKPIVSGNVLKLVSPHTMAGGKLIMKNSNILQMGKVTPNVMGGKPAFVITNKQGTPLGNQQIIIVTTGGNVRSVPTSTVMTSAGGSASGTNIVSIVNSTSTTPSPLQALSGQKTLISNQSGVKMLRNISSVQASSSMAFGQKQSGTPIHQKTALYIGGKAVTVMSTNTSMAASGNKVMVLPGTSSNNSPATTTALSARKSFVFNAGGSPRTVTLATKSINAKSIPQSQPVTETNNHSVATIKDTDPMDDIIEQLDGAGDLLKLSESEGQHGSEENENNGENATSSSASALFTGGDTAGPSRAQNPIVMEHPVDIIEDVSGVSSTTDVNETAIVSGDTIESLKMSEKENDDVKSMGEKSILSDDCHQPTTSETEAATILTTIKSAEALVLETAEIRKDHTGCTIGSLKENQDENKKFKQRQESSPSQNIHQFQNVDGSQLEALASAALLQAATSDTTALALKELIERPESETNTRSSNIAEIQQNNVQSTLAVVVPNTSQNENQKWHTVGVFKDLSHTVTSYIDSNCISDSFFDGIDVDNLPDFSKFPRTNLEPGTAYRFRLSAINSCGRGEWGEISSFKTCLPGFPGAPSAIKISKDVKEGAHLTWEPPPAQKTKEIIEYSVYLAVKPTAKDKALSTPQLAFVRVYVGAANQCTVPNASLSNAHVDCSNKPAIIFRIAARNQKGYGPATQVRWLQDPAAAKQHTPTVTPNLKRGPEKSTIGSSNIANTFCSPHKRGRNGLHD
Protein: Phosphatidylinositol 3-kinase 3 (PI3-kinase) (PI3K) (PtdIns-3-kinase) (EC 2.7.1.137) (P54675)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Phosphatidylinositol 3-kinase
- Phosphatidylinositol 3-kinase 2
- Phosphatidylinositol 3-kinase 1
- Phosphatidylinositol 3-kinase
- Inositol 5-phosphatase 4
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- phosphoinositide 5-phosphatase
- Probable phosphatidylinositol phosphate kinase DDB_G0267588
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- PIPK domain-containing protein
Sequence:
MRQIVTGVIHQTTQSQQIPNVINSNQIQFSNEPMVVGSIEDFDIDSEVPPLAINLQRSINNNNNNNNNNNNNNNNNNNNNNNNNNNNTQPCTTVFLDRDSCVNVKATIDLLKEQLEFTIKDLIDFKENYDKLESTEQFKQWSNLIKNIKENSLNNSNIYLTIPTTQNLINNNNNNNNNNNNNNNNNNNNNNNNNNNVIIPSASTENKEENDNNNSNNNNNINLSPDSSITKDINITENKITEIKTTETKETSTGTSPLEKSPSKGFIISPKKPEEENEIEGETINNIAITNYTQGPSMLTLMKKKLENIKKNNNNNNNNGNGNNNSNNNNSNSNNNNNGISPSSSPPSHLNGNNNNNNSNNTNSNNTTNATTNSVGFSITMTNSNSLSVSKRMNKFKSWTSSKPTSSSIGFASSPQNNGKPLNISGSSRFFTSRQDSKIDLLKSPSSSPPTQSDIFNENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEELINNNNNNNNDENYKIEETEESLKELLEKEKLENEEREKILKERNEIDNLKKKNHLSKGYFMRACNASNDDGLEEEDIPLQDEHWETNVIVLLPCRHHVKVPGSSSSSIDSIRQLAWASGKMQGHLNLEKDEKFFTLRWCNKDVVFDQDTPLGHLIQYNLNYNNPTQKPTNIKLELVLEDELCKERLVDLQSLEINNGRPSIWKSHIDDVLSFNRKLRELAMLAKPQSNVPAARLTPYPPPKTIPEFFVIRVHLFKNQTKSLRCANNHTAFSLMTILSEKLKNTTPFDPTQYRFLITGINQYVDPNVPLLSVEYIVEKIKRKGEIDLTMVELLSLGLIIQQQQQQQQQQQQQQQQQQIENIDDENILKLNNGILNVLSKIEKPIREKDNCISSLTVTENLQVRLLHAHEIFASKASEIIGTDSPSIQLFIEAAVYFGGELLATQSSKLVSFQDTVVWNEWVNIPLAVSNIPNGARMCLGLNARYRGDIFNIGWVGHRLFDSKGILNTFAPFSLLLWPGKINPIGTCVDNLESKDQAIIIAFEFKDYVVPKTIHYEDDLIELISKDENGNELPVVTMEEMDRVEQIILQDPLYSLNKEERLLIWKSRYFCHTKPQALSKLLQSVEWTNYKQVGEAFQLLKIWPTLSAVDALELLDPKFADCVEIREYAVKCLDQMSDYELEIYMLQLVQAIKHDVFHNSVLSLFLIGRVWQNMQVLGHPFFWHLRADIDNQEVCERFRVLSSGFLRYAPTQLMESFKREITTLRILENLAKRVKEVPYEKRKQYVENNLREEQSFPTELFVPFDPSIRILNIIPEKCKSMDSAKVPLWVTFKNADPFAPPLQMIAKTGDDLRQDILTLQLLRLMDHMWKSQDLDLHMTIYRCIATGMGTGLIEVVPNSETAARIQAGAGGVSGAFKQTPIANWLKNHNQTENSYQKAVSKFTLSCAGYCVATYVLGIGDRHNDNIMVDIHGHLFHIDFGHFLGNFKTFAGFQREKAPFVLTPDFVYVIGGKDSPNFAFFVDICCKAFNIIRSNAHVFINMFELMLSTGIPELRSENDIVYLRDKFRLDLTDAEASEYFKKLIHESIGTLTTTINFAIHIMAHRKNLVSGNSAPKIGSASSLNLNKNKPSSQSKLDLSRSDLSRSDSSRSDSSRLDLSRSDKKNNKDNKEKEKEKEKEKEKENNDNNDKDNNNNSNNDTEKENSIDK
Protein: Secreted frizzled-related protein 1 (Q7T2K9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Protein Wnt-1
- Protein Wnt-5b
- Protein Wnt
- Protein Wnt
- Protein Wnt
- Protein Wnt-11
- Protein Wnt-8a
- Protein Wnt-4a
- Protein Wnt
- Protein Wnt-2
Sequence:
MKSLASLSLWRIIILILPLVSLGQTFEYGWPDNYDKPPQCVDIPVDLRLCQGVGYHQMLLPNLLEHESMAEVKQQAGSWVPLLHKNCDPGTQLLLCSLFAPVCMERPIYPCRRLCENVRDGCSPIMAAFGFPWPHILTCDKFPQDDMCINTPNDTSTSEPNGHPPVCPPCDNEMKMDVILDHMCASEFAIKTKIQEVKRENMDRKVTLQKKKRTIKMGTLKKKDLKKLTLYLKNGADCPCTQLDNTRNTYLIMGRKVDKQYLLTGIHKWDKSNREFKKTMKKLKSHKCPAYENVFK
Protein: Protamine-like protein 99C (Q9VAF7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Regulates chromatin compaction in spermatid nuclei and is essential for male fertility. Functions in parallel with other chromatin-condensing proteins such as ProtA, ProtB and Mst77F.
Subcellular location: Nucleus {ECO:0000269|PubMed:26673329}. Chromosome {ECO:0000269|PubMed:26673329}. Note=Expressed in mature sperm chromatin. {ECO:0000269|PubMed:26673329}.
Interaction partners:
- Protamine A, isoform A
- Histone-like protein 18C
- GH11850p
- IP10875p
- FACT complex subunit spt16
- Testis-enriched HMG-box-containing protein 2, isoform B
- Transcription elongation factor SPT6
- GEO12017p1
Sequence:
MGRKRGRKEYCPPIYKRQKVARVTNNGYLNFMTEYKKRFYGLSPQDMVHYAAKQWTQLSMAEKEAFKSKKPSTITLKSPAQYVACEMKSDVAGGQQSSCQRQSPSARLRESERRSSRSKTLCRSAKNRQRGKPKPQQSKRRLSHMGSAVAYIHFLRKFQRKNTELRTIDLLKTATRLWCRLPERHRHAFERPLWIVTIGKS