wanglab/gogpt-training-data huggingface dataset:
Protein: Branched-chain amino acid permease BrnQ (BCAA permease) (Branched-chain amino acid transport system 2 carrier protein) (LIV-II) (P0AD99)
Organism: Escherichia coli (strain K12)
Function: Liv-II branched chain amino acid transport system, which transports leucine, valine and isoleucine.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Proline-specific permease ProY
Sequence:
MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTAAFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRTATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALVILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGVTEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFGGGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLSQLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAFSDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH
Protein: Dynactin subunit 5 (Dynactin subunit p25) (Q9BTE1)
Organism: Homo sapiens (Human)
Function: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0A286ZK88}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:23455152}.
Interaction partners:
- Alpha-centractin
- Dynactin subunit 4
- Dynactin subunit 6
- Dynactin subunit 2
- Dynactin subunit 1
- Actin-related protein 10
- Dynactin subunit 3
- Beta-centractin
- Cytoplasmic dynein 1 heavy chain 1
- F-actin-capping protein subunit alpha-1
Sequence:
MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQV
Protein: RNA-binding protein 24 (RNA-binding motif protein 24) (RNA-binding protein SEB-4) (Q76LC6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound. Involved in myogenic differentiation by regulating myog levels. Binds to a huge amount of mRNAs (By similarity). Required for embryonic heart development, sarcomer and M-band formation in striated muscles.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q6GQD3}. Cytoplasm {ECO:0000250|UniProtKB:D3Z4I3}.
Interaction partners:
- RNA binding protein fox-1 homolog 1
- RNA binding protein fox-1 homolog 1-like
- Coronin
- Small muscular protein
- Tumor protein p63-regulated 1.
- RNA-binding fox-1 homolog 2.
- Serine/threonine kinase 38b
Sequence:
MHTTQKDTTYTKIFVGGLPYHTTDSSLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMADRSAADRACKDPNPIIDGRKANVNLAYLGAKPRVMQPGFTFGVPQIHPAFIQRPYGIPTHYVYPQAFMQPSVVIPHIQPTATSATASSPYIDYTGAAYAQYASAATAAAAAAYEQYPYAASPAATGYVAAAGYGYAMQQPLATAAPGSAAAAAAAFGQYQPQQLQAERMQ
Protein: Expansin-A8 (AtEXPA8) (Alpha-expansin-8) (At-EXP8) (AtEx8) (Ath-ExpAlpha-1.11) (O22874)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity).
Subcellular location: Secreted, cell wall. Membrane; Peripheral membrane protein.
Interaction partners:
- Transcription factor PRE1
- Auxin-responsive protein SAUR15
- Xyloglucan endotransglucosylase/hydrolase protein 15
- Transcription factor PRE5
- Transcription factor IBH1
- Probable pectate lyase 22
Sequence:
MYTPSYLKYSIISIISVLFLQGTHGDDGGWQGGHATFYGGEDASGTMGGACGYGNLYGQGYGTNTAALSTALFNNGLTCGACYEMKCNDDPRWCLGSTITVTATNFCPPNPGLSNDNGGWCNPPLQHFDLAEPAFLQIAQYRAGIVPVSFRRVPCMKKGGIRFTINGHSYFNLVLISNVGGAGDVHAVSIKGSKTQSWQAMSRNWGQNWQSNSYMNDQSLSFQVTTSDGRTLVSNDVAPSNWQFGQTYQGGQF
Protein: Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related protein 4 homolog B) (OsAtg4) (Protein autophagy 4) (Q2XPP4)
Organism: Oryza sativa subsp. indica (Rice)
Function: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (By similarity). In addition to the protease activity, also mediates delipidation of PE-conjugated ATG8 proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8BGE6}.
Interaction partners:
- Autophagy-related protein 8A
- Autophagy-related protein
- Autophagy-related protein 8C
- Autophagy-related protein 8B
- Autophagy-related protein
- Uncharacterized protein
- Protein kinase domain-containing protein
- Protein kinase domain-containing protein
- Protein kinase domain-containing protein
- Ubiquitin-like protein ATG12
Sequence:
MTSLPDRGVSSSSSDPLCEGNIAPCSSSSEQKEDCSLKQSKTSILSCVFNSPFNIFEAHQDSSANKSPKSSSGSYDWLRVLRRIVCSGSMWRFLGTSKVLTSSDVWFLGKCYKLSSEESSSDSDSESGHATFLEDFSSRIWITYRRGFDAISDSKYTSDVNWGCMVRSSQMLVAQALIFHHLGRSWRRPSEKPYNPEYIGILHMFGDSEACAFSIHNLLQAGNSYGLAAGSWVGPYAMCRAWQTLVRTNREQHEVVDGNESFPMALYVVSGDEDGERGGAPVVCIDVAAQLCCDFNKGQSTWSPILLLVPLVLGLDKINPRYIPLLKETFTFPQSLGILGGKPGTSTYIAGVQDDRALYLDPHEVQMAVDIAADNIEADTSSYHCSTVRDLALDLIDPSLAIGFYCRDKDDFDDFCSRATELVDKANGAPLFTVVQSVQPSKQMYNQDDVLGISGDGNINVEDLDASGETGEEEWQIL
Protein: Pre-rRNA-processing protein SRD1 (Suppressor of rRNA-processing defect protein 1) (P09007)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Plays a direct or indirect role in pre-rRNA processing.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Putative uncharacterized protein YCL068C
Sequence:
MRYNNYDNSGSSFLTRVVKKSDMEKTLLLNREIDDWKSNDKKKAYKERGRVYASCSFIEVSFSQIRAVDVEKKIENAEQLRDLTRNIVKNKTSSLNEITPSKNRVTSACNSERRTTSQEANNLEGYHSCAQGTSRSASITKKYSKKTTSRPKREKRQTILPNGEIKECSKCKDTWTIQWRSGPDQNRELCSPCGLAYGKRLKKENEKKRQAADKRIDRNNP
Protein: Alpha-adducin (Erythrocyte adducin subunit alpha) (P35611)
Organism: Homo sapiens (Human)
Function: Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
Subcellular location: Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Interaction partners:
- Protein 4.1
- Dematin
- Beta-adducin
- Ankyrin-2
- Ankyrin-1
- Ankyrin-3
- Gamma-adducin
- Tropomodulin-1
- Tropomodulin-4
- Tropomodulin-2
Sequence:
MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
Protein: Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase) (P62942)
Organism: Homo sapiens (Human)
Function: Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:1701173}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:P62943}; Peripheral membrane protein {ECO:0000250|UniProtKB:P62943}; Cytoplasmic side {ECO:0000250|UniProtKB:P62943}.
Interaction partners:
- TGF-beta receptor type-1
- Regulatory-associated protein of mTOR
- Serine/threonine-protein kinase mTOR
- Ryanodine receptor 1
- Activin receptor type-1
- Calcineurin subunit B type 1
- Target of rapamycin complex subunit LST8
- Calmodulin-1
- Calmodulin-like protein 3
- Calmodulin-like protein 5
Sequence:
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
Protein: Developmental regulatory protein wetA (Q4WQL4)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Plays an essential role in the completion of conidial maturation and is essential for trehalose biogenesis in conidia. Negatively regulates expression of the melanin biosynthetic gene cluster. Also plays an a role in the early phase of fungal growth including proper hyphal branching.
Interaction partners:
- C2H2 type master regulator of conidiophore development brlA
- Conidiophore development regulator abaA
- Developmental and secondary metabolism regulator veA
- Cell pattern formation-associated protein stuA
- Secondary metabolism regulator laeA
Sequence:
MFAQPFDHAFNDLFSQYVDMDSSMVDGNKDVSIPSDFDQIFSLDSLSSDCGDHSPPVPTKPTHQSPQPWATDLWSLPQDAASSASQCSFTFQDTVHPSAVSDLSFHLEAPPTSHPVPAVTCKASSRSPSTPPATPHHKSTKSALVTPKSIRRHRDSHERKLLRKQSFSPSLMRPSQLQAGRMMYPEAWAQRFQNFSLHSSGEHLPLSPPPSDILVQHENTPADNVVTHMNHSTEGLSRNPAEMPSHYETGIFNQSPAISMPSPSAKLLAQQQQHNYLSQSNNSTMATSSPPSGDDIFSSPHSSDPQSLSSWHSDSLGGSALPFTPELQAHDGQAWWPSMPSRVPRQPSYQHVVSSPAPQRSIQSNNQHDLMQGGLMIQFDSSFDGSTSADPSFSSVVTSAPMPQENQNMYSHIPVTPQKYMNLSAYATPPVQHTSRSPSLSPRGRGSPTQGSPLRNEASTKTSPHRRGYHGRKLSSQSMNTPKPVKGPNSSSPGSGSNKSLTVSFVNFTPNDSKKILTGVAPSGSSKTKARREQEARDRRRKLSEAAINAVRKAGGDVEALEAVLC
Protein: TELO2 interacting protein 2 (E5RHM7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MELDSALEAPSQEDSNLSEELSHSAFGQAFSKILHCLARPEARRGNVKDAVLKDLGDLIEATEFDRLFEGTGARLRGMPETLGQVAKALEKYAAPSKEEEG
Protein: Vasculin (GC-rich promoter-binding protein 1) (Vascular wall-linked protein) (Q86WP2)
Organism: Homo sapiens (Human)
Function: Functions as a GC-rich promoter-specific transactivating transcription factor.
Subcellular location: Nucleus {ECO:0000269|PubMed:14612417}. Cytoplasm {ECO:0000269|PubMed:12842993}. Note=According to PubMed:12842993, it localizes to the cytoplasm. {ECO:0000269|PubMed:12842993}.
Interaction partners:
Sequence:
MAQHDFAPAWLNFPTPPSSTKSSLNFEKHSENFAWTENRYDVNRRRHNSSDGFDSAIGRPNGGNFGRKEKNGWRTHGRNGTENINHRGGYHGGSSRSRSSIFHAGKSQGLHENNIPDNETGRKEDKRERKQFEAEDFPSLNPEYEREPNHNKSLAAGVWEYPPNPKSRAPRMLVIKKGNTKDLQLSGFPVVGNLPSQPVKNGTGPSVYKGLVPKPAAPPTKPTQWKSQTKENKVGTSFPHESTFGVGNFNAFKSTAKNFSPSTNSVKECNRSNSSSPVDKLNQQPRLTKLTRMRTDKKSEFLKALKRDRVEEEHEDESRAGSEKDDDSFNLHNSNSTHQERDINRNFDENEIPQENGNASVISQQIIRSSTFPQTDVLSSSLEAEHRLLKEMGWQEDSENDETCAPLTEDEMREFQVISEQLQKNGLRKNGILKNGLICDFKFGPWKNSTFKPTTENDDTETSSSDTSDDDDV
Protein: Zinc finger (C2H2 type) family protein (Q9STI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MFSRFVLKSWRPKTQTTSLNSIKGFSFSSSSINPKPKIRVGVWWDLDNKPPASFPPYDAAVKLRTAASSFGTVKLMMAYANRHAFSYVPLEVREQRKDRKLLNKLENKGLVKPPEPYFCGVCDRRFYTNEKLINHFKQIHETENQKRMRQIESSKGHRRVRLVAKYSMKIEKYKRAARNVLTPKEGYGLADELKRAGFWVKMVSDKPDAADKALKEHLVEVMDKREVECVVLVSDDSDFAGILWEAKERCLRTVVIGDSNEGALKRVADVAYSWKEVTMGKAKKEVEKVVGKWKDRDVLKKLEWTYDPALEKERGGSCGVWDYEFDYDDEIENGTEVEPVEIGDGVDWWKIDTEDGVGSSRTCR
Protein: Neurogenin-2 (NGN-2) (Class A basic helix-loop-helix protein 8) (bHLHa8) (Protein atonal homolog 4) (Q9H2A3)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Achaete-scute homolog 1
- Paired box protein Pax-6
- Insulin gene enhancer protein ISL-1
- LIM/homeobox protein Lhx3
- Transcription factor SOX-1
- LIM homeobox transcription factor 1-alpha
- Transcription factor SOX-2
- POU domain, class 4, transcription factor 1
- Oligodendrocyte transcription factor 2
- LIM/homeobox protein Lhx1
Sequence:
MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSPASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI
Protein: Down syndrome cell adhesion molecule 1, isoform BM (A0A0B4K827)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVKQFFESQVYDEYVIKGNAAIFKCQTPSFVADHIDITDWIDTEGEVFTKNITDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVSSTAPKVPPLQSRPMIVPGHTDLSILCPAQGYPAPSFRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPKLAPLPVNSPLYVGDYYQLTCAVVHGDAPFNITWYYNNEPAGDLAGVTILMHGRRSSSLNIESVGGDHAGNYTCKGANRAGETTAETHLSVKVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase) (P35505)
Organism: Mus musculus (Mouse)
Interaction partners:
- Maleylacetoacetate isomerase
- Oxaloacetate tautomerase FAHD1, mitochondrial
- Homogentisate 1,2-dioxygenase
- 4-hydroxyphenylpyruvate dioxygenase
- Fumarate hydratase, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- V
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Tyrosine aminotransferase
Sequence:
MSFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHVFDETTLNNFMGLGQAAWKEARASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVGPGNRFGEPIPISKAHEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVSLKGEGMSQAATICRSNFKHMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVEQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA
Protein: Crossover junction endonuclease mus81 (EC 3.1.22.-) (P87231)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular location: Nucleus {ECO:0000269|PubMed:11719193}.
Interaction partners:
- Crossover junction endonuclease eme1
- Structure-specific endonuclease subunit slx1
- DNA repair protein rhp51
- RecQ-mediated genome instability protein 1
- DNA topoisomerase 3
- ATP-dependent DNA helicase srs2
- DNA repair and recombination protein rad22
- Exodeoxyribonuclease 1
- ATP-dependent DNA helicase hus2/rqh1
- DNA repair protein rhp54
Sequence:
MDCGNPLFLQWIQEWMEESTRRFPKSYQTWRKAYDSMKSCPITFHRPSQALALKGIGPTICAKLEKKWNAYCLENNIPISTHNEQNDSHVNANKSSSETSSEKPRSVKKPTTRKRKVYVPSYRSGAYSILCALYMLNKHEFATKPQIVTMAQPYCDSSFGSATDRNMRYTAWSAMKTLITKNLVYQTGHPSKYCLTDDGEEVCIRLAKVDDSFQRKHTVSNFSVSKSDDHDSSLCQPPNFVTSINKAGSSSDHGGELHVTYCPVDHNEVSDGVETDIDVDQVDSLTGIHDHHIINNEQLIDLTEQEKKQPNESNLSNLKIETVLFSNCTVFLLIDTREIRSPLDRNLIIDKLTNDFGVNCQVRSLELGDALWVARDMESGQEVVLDFVVERKRYDDLVASIKDGRFHEQKARLKKSGIRSVTYILEESSYDESFTESIRTAVSNTQVDQLFHVRHTRSLEHSVSLLAEMTKQINLFYEKRKTLAVIPDLSIEAKTYESLREQLLKIDPSTPYHISYHAFSSVLSKSSTLTVGDIFIRMLMTIKGISASKAIEIQKKYPTFMHLFEAYEKSSSSQERNLLLNKTCQGYGFQTIGPALSAKVASVFFPES
Protein: Mov34/MPN/PAD-1 family protein (F4JC55)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 6 homolog
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- Proteasome subunit alpha type-3
- 26S proteasome non-ATPase regulatory subunit 11 homolog
- BRISC and BRCA1-A complex member 1
- Proteasome subunit beta type-1
- 26S proteasome regulatory subunit RPN13
- Proteasome subunit beta type-4
- Proteasome subunit beta type-6
- 26S proteasome regulatory subunit 6B homolog
Sequence:
MSLTCVNMSEDVWLTCLTHALSTETEEIMGLLLGDIEYSKNGESATAMIWGASPQPRSDRQKDRVETNPEQLAAASAQADRMTISTGRTTRVIGWYHSHPHITVLPSHVDVRTQAMYQLLDSGFIGLIFSCFSEDANKVGRIQVIAFQSSDGKPNSIPKSMSLVLANKDSVIDIESSSSSSDSIYQRSSSSKPELDTIDTATTSGSKGGGRVSDFGPFFTNNIEANITGRDETHKSGNLSSTTIGIDSMDMSESMQEAMLRSNLDTSGAGYVRKEVPLHVLPTSSLLPVNSPLASFKSLQRVLYEEERAAYYQSVQQNMRDGRVHPLAFIHNTSTYQASMCKLIEYCLSPAINALQDRQKENKIRLAMLMDEAEVLEAQKLKGAETSRRPSHLVHGSGSRSRRGS
Protein: Putative glycoside/cation symporter YagG (P75683)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000305|PubMed:15919996}.
Interaction partners:
- D-xylonate dehydratase YagF
- Putative beta-xylosidase
- Uncharacterized protein YkfA
- Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE
- Uncharacterized protein YagN
Sequence:
MTQLTMKDKIGYGLGDTACGFVWQATMFLLAYFYTDVFGLSAGIMGTLFLVSRVLDAVTDPLMGLLVDRTRTRHGQFRPFLLWGAIPFGIVCVLTFYTPDFSAQGKIIYACVTYILLTLVYTFVNVPYCAMPGVITADPKERHALQSWRFFLAAAGSLAISGIALPLVSIIGKGDEQVGYFGAMCVLGLSGVVLLYVCFFTTKERYTFEVQPGSSVAKDLKLLLGNSQWRIMCAFKMMATCSNVVRGGATLYFVKYVMDHPELATQFLLYGSLATMFGSLCSSRLLGRFDRVTAFKWIIVAYSLISLLIFVTPAEHIALIFALNILFLFVFNTTTPLQWLMASDVVDYEESRSGRRLDGLVFSTYLFSLKIGLAIGGAVVGWILAYVNYSASSSVQPVEVLTTIKILFCVVPVVLYAGMFIMLSLYKLTDARVEAISRQLIKHRAAQGEAVPDAATAASH
Protein: VIT family (Q582S1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MDSFRLTEKDEARCSFGDPKRSRDAHDNRMEHFNVDIRKNSALRNRSLVCGCLTGFTCAAGAIGALAGMYRSSLGSTSQDKRFAPLLIAHAFSGGVGIAFTVCRSLLFERAVYEVELQRELWEIDNHIAGEIQEMVAIYRAQGLLEEEAHMITRIFAKHREAFANLMMVEELGYSRLEPPAGWEAVVDAAIPSSIGYTLGWVLPLLPFMGSELSSARSELVALCTLAAGIFVVSVGQSEVFFGSYANVWKAVGATVWNLSAAGLTYGATRFMACRSGV
Protein: Zinc finger protein 212 (Zinc finger protein C2H2-150) (Q9UDV6)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger protein 282
- Zinc finger protein 746
- Zinc finger protein 398
- Zinc finger protein 783
- Zinc finger protein 777
- Zinc finger protein 408
Sequence:
MAESAPARHRRKRRSTPLTSSTLPSQATEKSSYFQTTEISLWTVVAAIQAVEKKMESQAARLQSLEGRTGTAEKKLADCEKMAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGEAPKVSRSLENDGVCFTEQEWENLEDWQKELYRNVMESNYETLVSLKVLGQTEGEAELGTEMLGDLEEEGPGGAHPAGGVMIKQELQYTQEGPADLPGEFSCIAEEQAFLSPEQTELWGGQGSSVLLETGPGDSTLEEPVGSRVPSSSRTVGCPKQKSHRQVQLDQECGQGLKLKKDTSRPYECSECEITFRYKQQLATHLRSHSGWGSCTPEEPEESLRPRPRLKPQTKKAKLHQCDVCLRSFSCKVSLVTHQRCHLQEGPSAGQHVQERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCTECEKSFVQKQHLLQHQKIHQRERGGLALEPGRPNGLL
Protein: Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5) (P51870)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Interaction partners:
Sequence:
MPWLTVSGLDLGSVVTSTWHLLLLGAASWILARILAWTYSFCENCSRLRCFPQSPKRNWFLGHLGTIQSNEEGMRLVTEMGQTFRDIHLCWLGPVIPVLRLVDPAFVAPLLQAPALVAPKDTTFLRFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKHLCLEGSARLEMFENISLMTLDSLQKCLFGFDSNCQESPSEYISAILELSSLIIKRSQQLFLYLDFLYYRTADGRRFRKACDLVHNFTDAVIRERRRLLSSQGTDEFLESKTKSKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVFDPFRFDSENRQKRSPLSFIPFSAGPRNCIGQTFAMNEMKVVVALTLLRFRVLPDDKEPRRKPEIILRAEGGLWLRMEPLSTDTQ