Protein: Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form) (skNAC) (P70670)
Organism: Mus musculus (Mouse)
Function: Cardiac- and muscle-specific transcription factor. May act to regulate the expression of genes involved in the development of myotubes. Plays a critical role in ventricular cardiomyocyte expansion and regulates postnatal skeletal muscle growth and regeneration. Involved in the organized assembly of thick and thin filaments of myofibril sarcomeres.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12011100}. Nucleus {ECO:0000269|PubMed:12011100}.
Interaction partners:
- Transcription factor BTF3
- Small ribosomal subunit protein eS1
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein eL19
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL8
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL2
- Small ribosomal subunit protein eS6
Sequence:
MPGEATETVPATEQELPQPQAETAVLPMSSALKVAAVGQPGPTPPSSLGPQQSPIVTAHQPSPLPSSVSSTPFEVPFAQPITAETALPSGTAPPTPTFLPHLIGPPISPAALALASPMIGLAQKGARSSSAPLSLVALAPHSVQKSSVCPPHPLTSPPSAAGAELGALTASIPPLEPKTSTSQVPSQGTLNLKGTAPCPPDVVRAFPSHLENPLASVQPGLMSCPQTLSNTSPVKGVPISSALTQSRLSLNLKGPVSPPARNTAAPSIPLAPSTSLGCHLPLLHHSSVDSPIQPPGQSGLAVSNPTSVGHSGIAASCPPERCVVPALPSRLLAVDSGAAPSDDKGSSAVTNELCSPPGSSNVAGTSLSPKASLVPKGSNVALQPLVTQVPASQKTGLKEIPVSCIGATHHALDNPSAISVAPATHVPPPTSSGLVSSKDPASPVTSLVVPAAHKQFPAPPASATLGVPVSPLPATEGLKNLPISALVNVGAPVSPAQAGLPTRKDTTLQPLAPIALKESPSSQSASSLEVLSEDTVTKKTTGGPAPVVRPAIAGVATTTSLRADSPPAVIRADSCVSPNTVSQPLKRSVTDPAMAPRTAKNTAPSTTSPLVPLASEGCPVASSMALSPQNASVSETALALSPEIPKSVPFPDPPLAEISFSNARKVDAVSHMESSGSSRQGHPDASVTAKGTVVCLADSSLDTSVSASKGSALSGASSPLYPLEVSFLPEAGLAVQGPKGSLNKLSPTPPSSKGAPVPSTGAPPSPKGAPIVPTESSISSKQVPAEILPSPQKTPEVTASRLISAVQSPKVDPIMSDVTPTSPKKTSATAVPKDTSATLSLKSVPAVTSLSPPKAPVAPSNEATIVPTEIPTSLKNALAAATPKETLATSIPKVTSPSPQKTPKSVSLKGAPAMTSKKATEIAASKDVSPSQFPKEVPLLPHVPPTSPPKSPVSDTLSGALTSPPPKGPPATLAETPTYPKKSPKPAASKKTPATPSPEGVTAVPLEIPPCSKKAPKTAAPKESSATSSSKRAPKTAVSKEIPSKGVTAVPLEISLPLKETSKSATPGEKSASSPKRSPKTAGPKETPPGGVTAVPPEISLPPKETPQNATPNESLAASSQKRSPKTSVPKETPPGGVTAMPLEIPSAPQKAPKTAVPKQIPTPEDAVTILAGSPLSPKKASKTAAPKEAPATPSVGVIAVSGEISPSPKKTSKTAAPKENSATLPPKRSPKTAAPKETPATSSEGVTAVPSEISPSPPTPASKGVPVTLTPKGAPNALAESPASPKKVPKTAAPEETSTTPSPQKIPKVAGPKEASATPPSKKTPKTAVPKETSAPSEGVTAVPLEIPPSPRKAPKTAAPKETPAPSPEGATTAPVQIPPSPRKGSKKAGSKETPTTPSPEGVTAAPLEIPISSKKTSKMASPKETLVTPSSKKLSQTVGPKETSLEGATAVPLEIPPSHKKAPKTVDPKQVPLTPSPKDAPTTLAESPSSPKKAPKTAAPPSERVTTVPPEKPATPQKASATTASKVPVPAETQEVAVSSRETPVTPAVPPVKNPSSHKKTSKTIELKEAPATLPPSPTKSPKIPSSKKAPRTSAPKEFPASPSIKPVTTSLAQTAPPSLQKAPSTTIPKENLAAPAVLPVSSKSPAAPAAASASLSPATAAPQTAPKEATTIPSCKKAAATETPIETSTAPSLEGAPKETSETSVSKVLMSSPPKKASSSKRASTLPATTLPSLKEASVLSPTATSSGKDSHISPVSDACSTGTTTPQASEKLPSKKGPTAFTEMLAAPAPESALAITAPIQKSPGANSNSASSPKCPDPSSKKDTKGLPSAVALAPQTVPVEKDTSKAIETLLVSPAKGSDCLHSPKGPVGSQVATPLAAFTSDKVPPEAVSASVAPKPAPAASLTLAPSPVAPLPPKQPLLESAPGSVLESPSKLPVPAEEDELPPLIPPEAVSGGEPFQPILVNMPAPKPAGTPAPAPSAKQPVLKNNKGSGTESDSDESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM