wanglab/gogpt-training-data huggingface dataset:
Protein: BNI1-related protein 1 (P40450)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May organize microtubules by mediating spindle positioning and movement in the budding process. Potential target of the RHO family members (By similarity).
Interaction partners:
- Profilin
- Protein BNI1
- Cytokinesis protein 2
- GTP-binding protein RHO1
- Actin
- Bud site selection protein 14
- Bud site selection protein 6
- Kinesin-related protein SMY1
- GTP-binding protein RHO4
- Tropomyosin-1
Sequence:
MDSSPNKKTYRYPRRSLSLHARDRVSEARKLEELNLNDGLVAAGLQLVGVALEKQGTGSHIYMKQKNFSANDVSSSPMVSEEVNGSEMDFNPKCMPQDASLVERMFDELLKDGTFFWGAAYKNLQNISLRRKWLLICKIRSSNHWGKKKVTSSTTYSTHLATNELAENAHFLDGLVRNLSTGGMKLSKALYKLEKFLRKQSFLQLFLKDEIYLTTLIEKTLPLISKELQFVYLRCFKILMNNPLARIRALHSEPLIRWFTELLTDQNSNLKCQLLSMELLLLLTYVEGSTGCELIWDQLSILFTDWLEWFDKILADDIAIHSSLYLNWNQLKIDYSTTFLLLINSILQGFNNKTALEILNFLKKNNIHNTITFLELAYKDDPNSVVIMEQIKQFKSKESAIFDSMIKTTNDTNSLHPTKDIARIESEPLCLENCLLLKAKDSPVEAPINEIIQSLWKILDSQKPYSESIKLLKLINSLLFYLIDSFQVSTNPSFDETLESAENVDYVFQDSVNKLLDSLQSDEIARRAVTEIDDLNAKISHLNEKLNLVENHDKDHLIAKLDESESLISLKTKEIENLKLQLKATKKRLDQITTHQRLYDQPPSLASSNLSIAGSIIKNNSHGNIIFQNLAKKQQQQQKISLPKRSTSLLKSKRVTSLSSYLTDANNENESQNESEDKSKDSLFQRSTSTINFNIPSMKNITNMQNVSLNSILSELEFSNSLGTQPNYQSSPVLSSVSSSPKLFPRLSSDSLDNGIQLVPEVVKLPQLPPPPPPPPPPPLPQSLLTEAEAKPDGVSCIAAPAPPPLPDLFKTKTCGAVPPPPPPPPLPESLSMNKGPSNHDLVTPPAPPLPNGLLSSSSVSINPTTTDLKPPPTEKRLKQIHWDKVEDIKDTLWEDTFQRQETIKELQTDGIFSQIEDIFKMKSPTKIANKRNAESSIALSSNNGKSSNELKKISFLSRDLAQQFGINLHMFSQLSDMEFVMKVLNCDNDIVQNVNILKFFCKEELVNIPKSMLNKYEPYSQGKDGKAVSDLQRADRIFLELCINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFIITEIGNHMNKRIVKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQIIKKVKFKINRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIEKEEMERVYEQRKSLLDMRTSSNKKSNGSDENDGEKVNRDAVDLLISKLREVKKDPEPLRRRKSTKLNEIAINVHEGDVKTRKDEDHVLLERTHAMLNDIQNI
Protein: RNA helicase (EC 3.6.4.13) (O62372)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MADWGIAFDEQCRSEGLEVPEKTEKVQSGSEMDQNEENKGSNGWGISRGGMFGGPKASNAPPPQTSFGSTSGTRVGVPIMPGQSQPMRGGFQGAYRGGRGSGGGQMDFGAPGQGQSMGRGRGQQNPAFVPRPRDTPPQYGGHQAAQQFVKPDSKYKFTKPATEEAHEQVPVPADIALLNKFIQKEVKMMKDVVVDVQRQDPKSPLYSISSFRELRLKPEVLKALDTMNFQFPTRIQETALPLLLMEPPSNLIAQAQSGTGKTAAFVLTMLCRIDVNLMCPQCICLAPTLELAKQIGEVVEKMGKFIDNLKIHYAIKGGNMAAMRGRKLTEQIVIGTPGITRDYLQKYKCIDPSKIRCLVLDEADVMIYHQGFTDISTTIYNMVEDASDSVQSMLFSATYDEPVINFATKIIKNAIVVMLKREEQALPNIKQFYVQCACRDSKYAAIVNLYSGLAVASSVIFCHTKASVMWLYENMRARGHQVDVLHGDMTVVERADTIIHFKRGDFKVLITTNVFARGIDVAQVSVVINYDLPIKYTDEGTPMVVDGFTQPDCETYLHRIGRTGRFGKTGIAINLIDSEDSMNMINVLENHFQMKIARMDPSNLVELEAIEMA
Protein: Transcription cofactor vestigial-like protein 3 (Vgl-3) (A8MV65)
Organism: Homo sapiens (Human)
Function: May act as a specific coactivator for the mammalian TEFs.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8N8G2}.
Interaction partners:
- Transcriptional enhancer factor TEF-1
- WW domain-containing transcription regulator protein 1
- Transcriptional coactivator YAP1
Sequence:
MSCAEVMYHPQPYGASQYLPNPMAATTCPTAYYQPAPQPGQQKKLAVFSKMQDSLEVTLPSKQEEEDEEEEEEEKDQPAEMEYLNSRCVLFTYFQGDIGSVVDEHFSRALGQAITLHPESAISKSKMGLTPLWRDSSALSSQRNSFPTSFWTSSYQPPPAPCLGGVHPDFQVTGPPGTFSAADPSPWPGHNLHQTGPAPPPAVSESWPYPLTSQVSPSYSHMHDVYMRHHHPHAHMHHRHRHHHHHHHPPAGSALDPSYGPLLMPSVHAARIPAPQCDITKTEPTTVTSATSAWAGAFHGTVDIVPSVGFDTGLQHQDKSKESPWY
Protein: Mechanosensitive ion channel protein 4 (Mechanosensitive channel of small conductance-like 4) (MscS-Like protein 4) (Q9LPG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mechanosensitive ion channel protein 2, chloroplastic
- Mechanosensitive ion channel protein 3, chloroplastic
- Mechanosensitive ion channel protein 1, mitochondrial
- Protein MID1-COMPLEMENTING ACTIVITY 2
- Protein MID1-COMPLEMENTING ACTIVITY 1
- Casparian strip membrane protein 4
- Casparian strip membrane protein 5
- Tubby-like F-box protein 11
Sequence:
MAVDSTDQRRDFVVRIDGEDNGDSEKFWRESSINFWHNDKSSKPPGGEEDDGSFDFMRRSSEKSEEPDPPSKLINQFLNKQKASGDEISLDMEANMPELQKNTVPPLSSTAVSGSASPVTAPVTASYRNGTGDAIRRRQNRVTLSPSVKDGDSSEDEENRVDGSEVVKCTSNRSTMRTKTLMKMKTRSRLMDPPTPTYPDMVSGRTPRSGNLNPGFSGRNTKPGTPNQGGSKDLEEEEDPFSEEDLPEGLRKEKICVWVIIEWIFLILIIASLICSLVIPYLRGKTLWDLALWKWEVMVLVLICGRLVSSWIVKLFVYFVESNFLWRKKVLYFVYGIRKPVQNCLWLGLVLIAWHFLFDKKVEREMRSTVLKYVTKVLICLLVAVIIWLIKTLLVKVLASSFHMSTYFDRIQESLFTQYVIETLSGPPRIEIHIEEEKVANDVKTFEIVGRKLSPLGPKAVSSPPQVTVGSGRLQKSPSRVGKSPVLSRSGSKKEGGEEGIRIDHLQRMNTKNVSAWKMKKLMNVIKKGTLSTLDEQIQDTTTQEDDKATQIRSEFEAKLAARKIFQNVAEPGSRYIYMEDFMRFLSEDESERAMDLFEGASECHKISKSCLKNWVVNAFRERRALALTLNDTKTAVNRLHRIVDVLVSIVILIIWLLILGIATTKFLLVISSQLLLVVFVFGNSCKTIFEAVIFVFVMHPFDVGDRCEIDGVQMIVEEMNILTTVFLRFDNQKIVYPNSLLGTKPIANYYRSPDMQDAIEFFVHIATPPEKTTALRQRILSYVDNKKDHWHPSPMIVFRDMCGLNSVKIAMWPTHKMNHQNMGERYVRRGQLLEEIGRLCRELDIEYRLYPLNINVKSLPAATPITSDRIPPSWNQQRSV
Protein: Techylectin-5A (Q9U8W8)
Organism: Tachypleus tridentatus (Japanese horseshoe crab)
Function: Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MHNLRNILFVITLIGQKYGLTSSQNKELCDVTSSTGLLDSIKVMASHVKEQLKDKGTSEVAQPIVSPDPTDCADILLNGYRSSGGYRIWPKSWMTVGTLNVYCDMETDGGGWTVIQRRGNYGNPSDYFYKPWKNYKLGFGNIEKDFWLGNDRIFALTNQRNYMIRFDLKDKENDTRYAIYQDFWIENEDYLYCLHIGNYSGDAGNSFGRHNGHNFSTIDKDHDTHETHCAQTYKGGWWYDRCHESNLNGLYLNGEHNSYADGIEWRAWKGYHYSLPQVEMKIRPVEFNIIGN
Protein: GPI-anchor transamidase subunit 8 (GPI8) (Q388L3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- GPI ethanolamine phosphate transferase 3
- GPI inositol-deacylase
- GPI transamidase component GAA1
Sequence:
MLPMLLWLVANLFLAPAAEGFHGMNKTNTWAVILSSSRYFFNLRHTTNALAMYHLCRKHGMDDDHILVFLSDSYACDPRKPNPATIYGAPAQAEQPNLYGCNIRVDYASYDVGVRRFLGVLQGRYDENTPPSRRLDTDENSNIIIYAAGHSAEKFFKFQDSEFMSSTDIADTLMMMWEQRRYRKLVFLVDTCRALSLCLEIKAPNVVCLASSEAHLDSYSHHLDPPSGFTVITRWTFEFLEVLKDSKCRPENGEVTLLQKSFYDFNYGPERLSLPQPLSEPAHFDAVNRPNAVREWKMDEFFCEQDRDKIPVELRYDLF
Protein: N-terminal EF-hand calcium-binding protein 3 (Amyloid-beta A4 protein-binding family A member 2-binding protein) (X11L-binding protein 51) (mXB51) (Q9D6J4)
Organism: Mus musculus (Mouse)
Function: Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta (By similarity). May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3 (By similarity).
Subcellular location: Golgi apparatus {ECO:0000250|UniProtKB:Q96P71}.
Interaction partners:
Sequence:
MACAGLLTVCLLGPPAPQQPRHSAPAAGHALFQDVFRRADKNDDGKLSFEEFQNYFADGVLSSAELRELFSGIDDHLTDNLETEKLCDYFSTHLGVYRPVLAALESLNRAVLTAMDTTKLEYEQASKVDQFVTRFLLRETVNQLQALQTSLEGASDTLEAQAHGQRLDEETIKAQSRPCGSRRAGRRALRSISWSPSWSPGSSDTGRSSEAEQQWRLQVNRLQELIDQLECKAPRLEPTHEEDLTKGFDSHILVAQRQVQVAEDALQDFHRALCCYMNFTGAQSHCLHVSAQKMLDNAAFTLYEFWQDEASWRRHQQSPCSKAFQRTLIDHLQAPDTLTTVFFPASWWIMNNN
Protein: Wiskott-Aldrich syndrome protein family member (WASP family protein member) (M9NCT2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367034}.
Interaction partners:
Sequence:
MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIGDRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQCDKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAAGRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGNTVKPYNMLSHLENNSNVTKQTAVAIADMGVYDTRPPRPNSIELNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQSHALYGQTGQGVMSPEPIYGPGTPSRNKPRPSQPPPAPPSNGSGGGTPTASNANTPTRGRSMSTSRDALPPPPPVPDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSVQNANDMVMTQLSNTFHSIGMTGNQLNSLSDLPPPPPVPDQHSPKMSPPNAAPPPPPPPPPVEEGMGSGNQHTLRPHQILPKSLANGEMQQPGQQNGVPHIVAPKKMLPPFHDPRNDLMKAIRDGITLRKVEKSEQKEIERNAAPLDVASILARRVAIELSESEDSDSEDDSEGWMEPNETSA
Protein: Bone morphogenetic protein 4 (BMP-4) (Q90752)
Organism: Gallus gallus (Chicken)
Function: Negatively regulates the structure and function of the limb apical ectodermal ridge.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Bone morphogenetic protein receptor type-1B
- receptor protein serine/threonine kinase
- Bone morphogenetic protein receptor type-2
- Activin receptor type-1
- Activin receptor type-2B
- Activin receptor type-2A
- Uncharacterized protein.
- Sonic hedgehog protein
- Fibroblast growth factor 10
- Noggin
Sequence:
MIPGNRMLMVILLCQVLLGGTNHASLIPETGRKKVAELQGQAGSGRRSAQSHELLRGFETTLLQMFGLRRRPQPSKSAVIPSYMLDLYRLQSGEEEERSLQEISLQYPERSASRANTVRSFHHEEHLESVPGPSEAPRIRFVFNLSSVPDNEVISSEELRLYREQVEEPSAAWERGFHRINIYEVMKPLSERSQAITRLLDTRLVHHNVTRWETFDVSPAVIRWTKDKQPNHGLVIEVTHLHQAQTHQGKHVRISRSLPQGHGGDWAQLRPLLVTFGHDGRGHALTRRARRSPKHHGSRKNKKNCRRHALYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
Protein: Klarsicht, isoform I (X2JAH4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus membrane {ECO:0000256|ARBA:ARBA00004126}.
Interaction partners:
Sequence:
MSVLKSSLQRLGDKPTPELLDTEPAIQIAVEALKLEQTQLTSYRTNMLRLNASVHSWLTKQERRLQSALEEQEQQQESEQLKQQKLVEEEKGADVQKELASTGAVAITVTDSNGNQVEALATGEASTSTPAWDVHTLMSSEQEFHKHLKNEVSDMYSSWDEADARINTQLEMLTNSLIAWRQLESGLSEFQLALGQDRGTLKGLEGALDKGQATPVELAQNVKLVAKLLSEKVHVSQEQLLAVQQHLDPNHIYHITKFTASNGSLSDSGISDGGATSDGGLSERERRLGVLRRLAKQLELALAPGSEAMRSIAARMESAEADLKHLQNTCRDLIVRTAASHQQKQQIQQNQTQQVSPKANGHIKKQAAKGKAEPQSPGRRGKGARKARQAKKAGEDQQVEEPSLSPEQQKMVLKQLKTLTSGDGGDDPSDDPSLLFNLESSEEDGEGADPAQTSKRGWAWRIARAAVPMQVALFTIFCAACLMQPNCCDNLNNLSMSFTPQLRYIRGPPPI
Protein: Neuronal membrane glycoprotein M6-a (M6a) (Q812E9)
Organism: Rattus norvegicus (Rat)
Function: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells (By similarity). Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16286650, ECO:0000269|PubMed:21426347}; Multi-pass membrane protein. Cell projection, axon {ECO:0000269|PubMed:20074218}. Cell projection, growth cone {ECO:0000250|UniProtKB:P35802}. Cell projection, dendritic spine {ECO:0000269|PubMed:16286650}. Cell projection, filopodium {ECO:0000269|PubMed:16286650}. Cell projection, neuron projection {ECO:0000269|PubMed:16286650, ECO:0000269|PubMed:21426347}. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons (PubMed:21426347). Localized to plasma membrane of cell bodies and neurites of hippocampal neurons (PubMed:16286650). Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons (PubMed:16286650). Localized to the growth cone edge membrane of elongating axons (By similarity). {ECO:0000250|UniProtKB:P35802, ECO:0000269|PubMed:16286650, ECO:0000269|PubMed:21426347}.
Interaction partners:
Sequence:
MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGRCVSAWFIMLTYLFMLAWLGVTAFTSLPVYMYFNVWTICRNTTLVEGANLCLDLRQFGIVTIGEEKKICTVSENFLRMCESTELNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLNAYT
Protein: Pantothenate kinase (EC 2.7.1.33) (Pantothenic acid kinase) (P9WPA7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Coenzyme A biosynthesis bifunctional protein CoaBC
- Pantothenate synthetase
- Phosphopantetheine adenylyltransferase
- Type III pantothenate kinase
Sequence:
MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
Protein: Tubulin polyglutamylase TTLL11 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 11) (Q8NHH1)
Organism: Homo sapiens (Human)
Function: Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Preferentially mediates ATP-dependent polyglutamate long side-chain elongation over the initiation step of the polyglutamylation reaction. Preferentially modifies the alpha-tubulin tail over a beta-tail (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A4Q9F4}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A4Q9F4}.
Interaction partners:
Sequence:
MRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQLKWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS
Protein: 3',5'-cyclic-AMP phosphodiesterase 4C (EC 3.1.4.53) (cAMP-specific phosphodiesterase 4C) (Q3UEI1)
Organism: Mus musculus (Mouse)
Function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:21670265}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit alpha
- Adenylate cyclase type 5
- Adenosine kinase
- Adenine phosphoribosyltransferase
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
- GTP:AMP phosphotransferase AK3, mitochondrial
- Deoxycytidine kinase
- Adenylosuccinate lyase
Sequence:
MRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAESAAHVVFTIGTQGTQRNLGSAQSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRESFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQVLLGTPPHSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQVSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPPHTMGSDRFKFELTLEEAEEEEEEEDEGQCTALNRESSELPST
Protein: Protein Wnt-8b (XWnt-8b) (P31291)
Organism: Xenopus laevis (African clawed frog)
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in the initiation of dorsal axis development. May activate a Nieuwkoop center-like signaling pathway.
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
Sequence:
MFYTGSFWFIFFILPAIPFCHSWSVNNFLMTGPKAYLIYSSSVAAGAQSGIEECKYQFAWDKWNCPERTLQLSSHSGLRSDLNIHSTGASPAGSGLYDTGPTSPVWSINFNRILFSRLESHFNKTFLSRLQIPFPQGHTVQSATSLSTGFLSPANRETAFVHAISYAGVMYTLTRNCSLGDFDNCGCDDSRNGQLGGQGWLWGGCSDNVGFGETISKQFVDPLETGQDARAAMNLHNNEAGRKAVKSTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGNYLKEKYHKALKVDLFHGAGNSAASRGAIAETFRSISKKEIVHLEDSPDYCLENKTLGLLGTEGRECLKRGKALSKWEKRSCRRLCGDCGLAVKERRADMVSSCNCKFHWCCAVKCEQCRKSVTKYFCVKKEKRGGGIPRKKESKLKKKL
Protein: tRNA-specific adenosine deaminase subunit tad3 (tRNA-specific adenosine-34 deaminase subunit tad3) (Q9P7N4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Deaminates adenosine-34 to inosine in many tRNAs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- tRNA-specific adenosine deaminase subunit tad2
- tRNA
- tRNA
- tRNA
- Multifunctional methyltransferase subunit trm112
- 18S rRNA
- tRNA
- tRNA
- Putative tRNA pseudouridine synthase C16C4.06c
- tRNA N
Sequence:
MVKTNISKNSPKEATVPELDWPFKLIKSHLETRKLETENVWIACFEPKYASKVTQYVKQIRSKQKESLLHCNRLRRIQDENGSLELQIIICPEKSMTANEIGKDFEDLGIVSKMIFLYAVPAFPPLTDEQFHEWNSVWPVSYRKHVQRQDVFTVHELKRIESILEDLINAAGASHKHGEIGCAAAIYDPTTDTVLAVSVDERSKLKNPINHCVMNAINLVAKRELSRRQNRTDGSKDRYLCKDLTVVMTHEPCVMCSMGLLHSRIRRLIYCKKQPLTGGIESLYGIHWRAELNHRYLAYSGWNKPVPSIKENIHV
Protein: LETM1 domain-containing protein YLH47, mitochondrial (LETM1 homolog) (Q06493)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15138253, ECO:0000269|PubMed:16476776, ECO:0000269|PubMed:16823961}; Single-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15138253, ECO:0000269|PubMed:16476776, ECO:0000269|PubMed:16823961}.
Interaction partners:
- Large ribosomal subunit protein uL22m
Sequence:
MLKYRSLPIKRAIHHPAPGITPISPRIMVSRLRVIPSFNLKFNRWNSSVPESSKKELKTTDGNQESASKVSPVKEKEKVPFKVKMQKALRHYWDGSKLLGLEIKISSKLLMKSAAGYPLTRRENLQLKRTTQDIVRLVPFAAFLIIPFAELLLPFALKLFPNLLPSTYESSKKRENKLENLRNTRKLMSEIIKNNKSHFKPNNISEEQKALFNRFYTHVRATGVPESRQQLIEVARLFTDDTVLDNVTRPYLIALAKYMNLQPFGTDVMLRYRIRYKMLELKKDDLSIYYEDAEQLSLSELKTACASRGIRSVDVEPSVLYSNLRLWLNMRLKDKIPSTLLIMATAYNYGNVQSKESLYDALCDVLIGIPDELYHEVKVNVVKEDEASAKQKLKQLREQEEIMKEEEQQEENAIVSVKDELSLDDQDKNIDAAAPDVKPHDTKPIGEAAAIKEK
Protein: Ras-related protein RABA1a (AtRABA1a) (Ras-related protein Ara-2) (Ras-related protein Rab11E) (AtRab11E) (P28185)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in auxin-mediated response. May be involved in vesicle trafficking of components involved in polar auxin transport. Binds GTP and GDP and possesses intrinsic GTPase activity.
Subcellular location: Cell membrane {ECO:0000305|PubMed:19199049}; Lipid-anchor {ECO:0000305|PubMed:19199049}. Note=Located in the plasma membrane and endocytic vesicles derived from the plasma membrane.
Interaction partners:
- Rab escort protein 1
- Kinesin-like protein KIN-14E
- Protein YIP
- Protein YIP4a
- V-type proton ATPase subunit a1
- Mevalonate/galactokinase family protein
- Trafficking protein particle complex II-specific subunit 120 homolog
- ADP-ribosylation factor
- Geranylgeranyl transferase type-2 subunit beta 1
Sequence:
MAGYRADEEYDYLFKLVLIGDSGVGKSNLLSRFTKNEFNLESKSTIGVEFATKTTKVEGKVVKAQIWDTAGQERYRAITSAYYRGAVGALLIYDVTRHATFENAARWLRELRGHTDPNIVVMLIGNKCDLRHLVAVKTEEAKAFAERESLYFMETSALDATNVENAFTEVLTQIHKIVSKRSVDGGGESADLPGKGETINVKEDGSVLKRMGCCSN
Protein: Potassium/proton antiporter CemA (Chloroplast envelope membrane protein A) (CemA) (P0C303)
Organism: Oryza sativa subsp. indica (Rice)
Function: May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01308}.
Interaction partners:
- Photosystem I assembly protein Ycf4
- Photosystem II reaction center protein Z
- Photosystem I assembly protein Ycf3
Sequence:
MKKKKALPSFLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSQTLLTAIQEKRVLERFMELEDLFILDEMIKEKPNTHVQNPPIGIRKEIIQLAKIDNEGHLHIILHFSTNIICLAILSGSFFLGKEELVILNSWVQEFFYNLNDSVKAFFILLVTDFFVGFHSTRGWELLIRWVYNDLGWVPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
Protein: Uncharacterized protein, isoform B (X2JDB2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Accessory gland protein Acp32CD
- ACP53C14A
- Uncharacterized protein
- Accessory gland protein Acp36DE
- Accessory gland protein Acp62F
- Accessory gland protein Acp53Ea
- Accessory gland-specific peptide 57Da
- ACP53C14B
- Accessory gland-specific peptide 26Ab
- Serpin 38F, isoform A
Sequence:
MKFLTVFAFACGIVILLVATFVVLHGAYGSPLPEPIPDPSPVADPSPAANPSPVADPKPVAEPSANPGTGTNAEPGPRSKPNPSPSAPATLLEANKQDNFAVPLLETAPQKLDDVQADPQPA
Protein: Transcription activator TEC1 (Q5ANJ4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Transcription factor which regulates genes involved in hyphal development, cell adhesion, biofilm development, and virulence. Plays a role in the formation of 'finger' morphology, a unique multicellular morphology of C.albicans induced by carbon dioxide. Regulates gene expression during intestinal colonization. Required for the expression of the secreted aspartyl proteinases SAP4, SAP5, and SAP6; but also of BCR1, PGA4, and CDC24. Moreover, a positive feedback loop between CDC24 and TEC1 contributes to an increase in active CDC42 at the tip of the germ tube which is important for hyphae formation. Regulates also the pheromone response of the white cell phenotype.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor CPH1
- Enhanced filamentous growth protein 1
- Biofilm and cell wall regulator 1
- Transcriptional regulator NRG1
- Biofilm regulator 1
- Transcription factor ROB1
- Transcription factor NDT80
- Hyphal wall protein 1
- Agglutinin-like protein 3
- Transcription factor CPH2
Sequence:
MMSQATPSATPVRNADGQKKGKKLPLIVDVAIGNNGKQLYQVHESSKMVRKEMPRSTNFALNDDISDEGFFISQINEQRTPIRKTLGTLSPSSLNQKRIRHDVYDQGDDNSNDDNCQNDVYEQQQQQPQQQQQQQQQLHQPNMYENGNVGVISNDPVSSVGHYDNNPVSHVPTGAYSRVQDTDIWSDDVEEAFEEVLRLIPKSGLNKIKIAGRSCGRNELISDYIFAKTGKFRTRKQVSSHIQVIKNLGQKLDIIQLINDGPIFNSHEEQLESTKKFEDVFSKINLNKSLGFSDSMKRKSDSMPMHLPATKRIRRKHSGNPLNKIKFSNFFMSVNDQYGMNPIVLTIQQNGNDVKSLKLKDNANISSRFPGLSDFKSCPHIPIIHNMVKILLPQLPESYSIDDGFSSSYALKYEEPENASPTHTSIISSSRTYSLFTCVYSYGKEIVKFDEDGIQLNQDREFIPGFWKFFFSTFGDQSEGGLSAAFKGVTIKQILYESSPDSVKKEQDASKVNKSKVKLVLLWEFAKVSECKDALTTTTKLVLPPRASASSSKTTEEVFEYSEPALNSIGGTPTDTTSPNMDLNNQNLSAAATSIPGIRDTIHSASMPDINELPSSAKPQVRLQKTFQSMQHLQPHQMWQQQQQQQPSQGAYTSSVASQSLNTSLSSPYAQYGMPLPQQTIGTFVPPTSQTFGVSYTHNSQHPSANMDLMMLSSMNTGYGNITNNQDYQFGNIGYTEGFTSEF