wanglab/gogpt-training-data huggingface dataset:
Protein: UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (Cyanobacterial UDP-glucose pyrophosphorylase) (UDP-glucose pyrophosphorylase) (UDP-Glc PPase) (P74285)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. Is highly specific since it cannot use other NTPs such as dTTP, CTP, ATP, and GTP, and other sugar-1P such as GlcNAc-1P, Gal-1P, and Man-1P, as substrates. Has probably a central and essential role as the substrate supplier for galactolipid synthesis; galactolipids are major constituents of the photosynthetic thylakoid membrane and important for photosynthetic activity.
Interaction partners:
- Mannose-1-phosphate guanyltransferase
- mannose-1-phosphate guanylyltransferase
- D,D-heptose 1,7-bisphosphate phosphatase
- GDP-mannose 4,6-dehydratase
- GDP-mannose 4,6-dehydratase
- gluconokinase
- Slr1508 protein
- Monoglucosyldiacylglycerol epimerase
Sequence:
MKAMILAAGKGTRVRPITHTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEIESYFRDGQRFGVQIAYSFEGNIVDGDLVGKALGSAGGLKKIQEFNPFFDDTFVVLCGDALIDLDLTTAVKLHREKGAIATIITKTVPQELVSSYGVVVTDDNGKILTFQEKPAVEEALSTEINTGIYIFEPEVIDYIPSGQEYDLGGDLFPKLVDSGLPFYAVNMDFEWVDIGKVPDYWQAIRGVLSREIKNVQIPGIEVRPGVYTGINVAANWDNIEIEGPVYIGGMTRIEDGVKIIGPSMIGPSCLICQGAVVDNSVIFEYSRLGPGARLVDKLVFGRYCVDKTGAAIDVQAAALDWLITDARHAAVQYRQEYPSQREISKLLQPE
Protein: Retinoic acid receptor RXR-beta-A (Nuclear receptor subfamily 2 group B member 2-A) (Retinoid X receptor beta-A) (Q7SYN5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-cis retinoic acid (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Nuclear receptor subfamily 1, group H, member 3
- Retinoic acid receptor RXR-gamma-B
- Retinoic acid receptor RXR-alpha-A
- Peroxisome proliferator-activated receptor gamma
- Retinoic acid receptor alpha-A
- Retinoic acid receptor alpha-B
- Novel protein similar to tapasin
- Ral guanine nucleotide dissociation stimulator-like 2.
- Proteasome subunit beta
- Flotillin
Sequence:
MGDSRDSRSPDSSSVSSPPSGQRSPPLAPSAAAMTSLPPITSAVNSPISSMGSPFSVISSSLGSPCLPGTPSVGYGPISSPQINSTVSMSGLHAVSSSDDVKPPFGLKPLSSHSPGPMVSQKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLSYTCRDNKDCLVDKRQRNRCQYCRYQKCLAMGMKREVVQDERQRSVQEERQRNKERDGEVESSSAANEEMPVEKILEAEMAVEQKTELHADGSSGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELSLDDQVILLRAGWNELLIASFSHRSITVKDGILLATGLHVHRNSAHSAGVGAIFDRESAHNAEVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIILFNPDAKGLSSPSEVELLREKVYASLEAYCKQRYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLT
Protein: Striatin Pro11 (Q70M86)
Organism: Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
Function: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity). Required for the formation of mature fruiting bodies during early sexual development.
Subcellular location: Membrane {ECO:0000269|PubMed:14871953}; Peripheral membrane protein {ECO:0000269|PubMed:14871953}.
Interaction partners:
- PRO22 protein
- WGS project CABT00000000 data, contig 2.5
- Serine/threonine-protein phosphatase
- WGS project CABT00000000 data, contig 2.2
- WGS project CABT00000000 data, contig 2.4
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit eta
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit epsilon
Sequence:
MGTNGVHVSFGAGHEMGGVMGNGSGQPPATEYTLQGVMRFLQTEWHRHERDRNAWEIEKQEMRARIANLEGQARRADATQKALKRYVSILEKKVKEQSAALKSGGKEKGVEDEAEAEDNKTKLDRSALIQEKLRPNTKLSGAPNEAENVEIGPPDDESARNELKTFLDQCQAEFTYLMVTPANPQPPRESPPLPILDDFREGEALNQQLEQSYQRSQQSQIRDLLAQQAAAANATNVAAVQSQQQQPQQQQHAVGPRPQTNQPPKGYGELAQGAPMERSSRGQQLHDILKSGETPDWSASMQSQPVEEPTSALSKAPPMVRGDGREPAVPKSASTTDAWDFNESNFQDPNAMPQPTPQQSFSSRPDTDAFPSAENLTKSPNRGALSHRRKSSSGMARRRSAEHELSLGSLQQKAEGTMFKFRFGLRGHLDVVRTVIFSGGGSPGEPEICTAGDDGLVKRFHIPDRHIGQRNADGDLDVAADFTHRGHSGAVLSLASWSPSPNFSTGGRAQGDGWIFSGGQDATIRVWERGRVDPKATLDGHTDAVWALCVLPTNLGAIFGQTNSHGPPDRILLVSGAADGTVKVWAVSAPPQLTSPQPGPGRRGPGGRVRGNSMSSGSAFPSSPQPTTASNSPFHHTLVHTIKRANSEASPTCITALSPNGETFAVSYADAAIIVYDTRSGEEIGTMASLDTYDGTNNTAVNAVVATTVGLDQTQGPGGEDESGGGPTGGGRSMAGSGVEGTIISGHEDRYIRFFDANSGQCTYNMLAHPGSVSSLSLSPDGRELVSAGHDMSLRFWSLETRSCTQEMTCHRSMRGEGVCAVVWSQDGRWVVSSGGDGMVKVYAR
Protein: Enhancer of polycomb-like protein (F4JV27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU361124}.
Interaction partners:
Sequence:
MENRLGNSNGVGISKKSRSLDLKTLYKSSISKDSVNKSFKRKHRSGIDGDQLKQDKKSRKVVSLSSFKKVGSQNESILDKACNGTTILHNLEDSKEVGLDEKLCDSNGLQVISVGLASSTIYVPRRRRDFVGRSRFENGLAQKSAGESDSQEELVVNIPKVTAEESSVQDQPSKVEEKDSDKDIKESNSAAPLQLENGHSNQSPVKDDQLVVVKQRNSNSRKRKSSASNRRVGKEAKSSGDASGRISKVSREDDEENLEANAAIMLSSRFDPNCTQFPSNSVTPGSPSASRLHPLPSGKNSVDPRSELLSSKCVSDDTDDRMLRPRRHNDDGKGKVRKRRHFYEILFSDVDSHWLLNKKIKVFWPLDERWYHGFVDGFDGDKNLHHVKYDDRDEEWINLQGERFKILLFPSEVPGKNQRKRRCSESKSTQKVKGNDTSSKDEEKQKEKLEDDSCMESEPIITWLARSRHRDKSSTLKAVQKRKKTDVMTSNESVKMNGDVTDRSASSLASCGLPGPSKNELESSGFRNGSIFPIVYCRRRLHTAKKDIYKESGYNSVEFLKQFLVSKSPDPGVEFLPIEDSGDLELCCPWNESEQFELSLSLQGVSLMSYFLMADVDWLSRAALLLRHGTLVTLWPRVRLEMIFLNNQDGLRYLIFEGCLMEVVQLIFRILMVVDHSNKQGAQGADADLQLPVFSIGLQVSCIPGFQRQLGFQIYSFHEVKHSKWSYLEQNVRRHSLLVKQVSIAECTHNNMKVLQKVMQKRSRHGISSGLVSRGSSSAEAWPTSVCYKKQNTSPFALLFTARPPTLLLSLHLNMIRELGHDSADFLGIERDLVTHRGCDMADFTNEHSELSLKSKSQTDEPIITSSRAQESKDLHTPSQSQQLGSDSENWMSYSSSVVRHKHETRSNVSVNGISIQVPISDDCEDGTPQSSNLALNIQGSSNSSPKATAPRSMWNRSKSSLNGHLSHGWSDSKGDFLNTNLANGPKKRRTQVSYSLPSGGSDSRNKGSLLKGMPNKRIRRSTADVTKGIQKDLESSLCDANVLVTLGDRGWREYGAQIFLEPFDNNEWRLAVKISGTTKYSHRAHQFLQPGSVNRFTHAMMWKGGKDWTLEFPDRGQWFLFKEMHEECYNRNTRAALVRNIPIPGIRMIERDNFDGTETEFIRSSSKYFRQTETDVEMALDPSRVMYDMDSDDEQCLLRIRECSSAENSGSCEITEDMFEKAMDMFEKASFVKQRDNFTLIEIQELTAGVGSLEAMETIYELWRTKRQRKGMPLIRHLQPPLWEKYQRELKDWELVMSKANTPNSCGSQKKQSPTEKPAMFAFCFKPRGLEVKHRGTKHRSQKKLSVYAQHSSALGDYDGCNSSAGRRPVGFVSGDERFLYSNQSYEHSNEFSVHPGTYSPRDLGMGYFSSGGNGYHRNHQNKSQRINGKRNTSERWDAGYSECPSSNLVCYSNGSQRPDVEGIRNSTDIDEYKLRDAAGAARRACALAKLKRERAESLRYKADLAIQKAAAALMCAEAVKASSEDLGNNNGVESSSEG
Protein: Olfactory receptor (Q7TRM9)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
Interaction partners:
- Guanine nucleotide-binding protein G
Sequence:
MTWGNWTTVREFILMSFSSLSYEVQALLFLLFLIIYLVTLMGNVLIILVTTADSALQSPMYFFLRNLSFLEIGFNLVIVPKMLSTLILQDKTISFLGCATQMYFFFFFGAAECCLLATMAYDRYMAICDPLHYPIIMSRRSCAQLAAASWFSGFPVATVQTTWIFSFPFCGPNMVNHFFCDSPPVIALVCADTSLFELEALTATVLFILFPFLLILGSYVRILSTIFRMPSAEGKRKAFSTCSSHLLVVSLFYSTAILTYFRPRSNTSPENKKMLSLSYTVVTPMLNPIIYSLRNNEVKAALRRIIHRTLGPQKL
Protein: Ro60, Y RNA binding protein (TROVE domain family, member 2, isoform CRA_a) (G5E9R9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MPLTALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI
Protein: Granule associated Rac and RHOG effector protein 1 (GARRE1) (O15063)
Organism: Homo sapiens (Human)
Function: Acts as an effector of RAC1. Associates with CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. May also play a role in miRNA silencing machinery.
Subcellular location: Cytoplasm, P-body {ECO:0000305|PubMed:29395067}.
Interaction partners:
- Nck-associated protein 1
Sequence:
MYCCSAQDSKMDYKRRFLLGGSKQKVQQHQQYPMPELGRALSAPLASTATTAPLGSLTAAGSCHHAMPHTTPIADIQQGISKYLDALNVFCRASTFLTDLFSTVFRNSHYSKAATQLKDVQEHVMEAASRLTSAIKPEIAKMLMELSAGAANFTDQKEFSLQDIEVLGRCFLTVVQVHFQFLTHALQKVQPVAHSCFAEVIVPEKKNSGSGGGLSGMGHTPEVEEAVRSWRGAAEATSRLRERGCDGCLAGIEVQQLFCSQSAAIPEHQLKELNIKIDSALQAYKIALESLGHCEYAMKAGFHLNPKAIEASLQGCCSEAEAQQTGRRQTPPQPMQCELPTVPVQIGSHFLKGVSFNESAADNLKLKTHTMLQLMKEAGCYNGITSRDDFPVTEVLNQVCPSTWRGACKTAVQLLFGQAGLVVVDTAQIENKEAYAPQISLEGSRIVVQVPSTWCLKEDPATMSLLQRSLDPEKTLGLVDVLYTAVLDLNRWRAGREQALPCIQIQLQREICDFGNQADLPSGNGNKSSGGLQKTFSKLTSRFTKKASCTSSSSSTNYSIQNTPSKNIFIAGCSEEKAKMPGNIDTRLQSILNIGNFPRTTDPSQSAQNSSNTVANGFLMERRENFLHGDDGKDEKGMNLPTDQEMQEVIDFLSGFNMGQSHQGSPLVTRHNSAATAMVTEQKAGAMQPQQPSLPVPPPPRAPQAGAHTPLTPQPGLAPQQQSPKQQQPQVQYYQHLLQPIGPQQPPPQPRAPGKWVHGSSQQPAQAVGAGLSPLGQWPGISDLSSDLYSLGLVSSYMDNVMSEVLGQKPQGPRNNTWPNRDQSDGVFGMLGEILPFDPAVGSDPEFARYVAGVSQAMQQKRQAQHGRRPGNPRGNWPPMDDAHRTWPFPEFFTEGDGLHGGWSGAQGDSASSSDETSSANGDSLFSMFSGPDLVAAVKQRRKHSSGEQDTSTLPSPPLLTTVEDVNQDNKTKTWPPKAPWQHPSPLPSTLPSPSAPLYAVTSPGSQWNDTMQMLQSPVWAATNDCSAAAFSYVQTPPQPPPPPAHKAAPKGFKAFPGKGERRPAYLPQY
Protein: FA core complex associated protein 100 (E7EVV8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MHHPAPAWPRCGWCASHTWQISLGPRSTSFILCPLSSCGPRGEVRSDGWRQLPERLGVGGAGRNMPLGRGLTLWRGSTPTVCLSWSQARCLPGLSQDVAPGAVGVPPLPGVMSVLRRVSFLKKAVDQRNKALTSLNEAMNVSCALLSSGTGPRPISCTTSTTWSRLQTQDVLMATCVLENSSSFSLDQGWTLCIQVLTSSCALDLDSACSAITYTIPVDQLGPGARREVTLPLGPGENGGLDLPVTVSCTLFYSLREVVGGALAPSDSEDPFLDECPSDVLPEQEGVCLPLSRHTVDMLQCLRFPGLAPPHTRAPSPLGPTRDPVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQATQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL
Protein: Organic anion transporting polypeptide 30B, isoform A (Organic anion transporting polypeptide 30B, isoform B) (Organic anion transporting polypeptide 30B, isoform C) (Q9VLB3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MSAKHIEQYTNPSFEQESDQPPDPLGGVADVGAGNASSSSNGHIANDAGTANRKGHRRQESMYQMTGLYSETNSGDDSSIDAALDHDSQPHATSYLAGDQLPSTVGSGPGGGGPSAVADSVTVKCHSRQASAGKCPADPEEDFDEEQFRSGDCGILNCRPYGIQRFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVITVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHFTGEPNPGIAIVNKTSDNICKSALVRDQDMDLGRLSSGLSNQPLAPHTLREDNCLEGKASTTGPVLLFVLAQLLLGCGGSPLFTLGTTYVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFHMDSLSSTTISITPGDRRWVGMWWGGFLLCGVILLVVAVPFFSFPKVLAREKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLEIVAVTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKYLETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFFLGCDNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHAGCTAFSSTSNTNYTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVATAGPCATPCRTIYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGNLIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRKQLEKMKPLNASDPIIGSIISLDKLFEEKLSGAEPSTAFVGGGGELIIPTDILRHSRNDSRTMHMDYCYDKCGRVVTPANTCNQPQTKSKKHFRSASCDVKMIKSFARDHSSSSGPADAAGQDAVGASTKYKNLKKFQAHTRNHSTDLHDPSQPIRYIQNQLRPQDCPEEDDDEELTTGCGHFVKKHSRNHSYDQIYMPNNIRFDADFLRHPHSHHNPKKNVNVLKNVVSDVGKLKNSNEIEAGGAGSRGHSRNNSKDLNTKISSATPASGQVVTDASTTGLSVLRHRRTNSKDLNYQVLPESAASSSVSGHAHPQHTRNTSHHKIQIDDDRNELINDNDDEEEERSACA
Protein: RGD1564327 protein (B5DEG1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Interaction partners:
- Aa1018
- Integrin beta-1
- Nephronectin
- Integrin beta-6
- FRAS1-related extracellular matrix protein 2
- Integrin beta-3
- Extracellular matrix organizing protein FRAS1
- Fras1-related extracellular matrix 1.
- Fibronectin
- Tenascin
Sequence:
MSARTHRGPPENWAPPFACLCCVSAVLGMLWSPVSLAFNLDVDKLTVYSGPEGSYFGYSLDFYIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAERSAQCKQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVRAHKGKVVACAPLYHWRTLKPNPAKDPVGTCYVAIQNFSAYAEHSPCRNSNVDPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITVSVADIIANYSFKDILRKLAAEKQTDVAPASYDDSYLGYSVAAGEFTGDSLQELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVYLYLQVSALLFQDPQVLTGTETFGRFGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNARGLHSKPSQVLQGIWGSQTIPSGFGFSLRGDADIDKNDYPDLLVGAFGEGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQIPEFPTPVACFSLRVCASIAGQSISNTVALMAEVQLDFLKQKGAIKRTLFLHNHQSHLIFPFVMRQQKSLHCQDFMVYLRDETEFRDKLSPINVSLNYSLDDSTFEDGLEVKPILNHYRENVVTEQAHILVDCGEDNLCVPDLRLSARPDKQEIIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGLRLLSCEYKMENVTRMVVCDLGNPMVTGTNFSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSVQINVTAVAQVEIRGVSHPPQIVLPIHNWEPAEEPHKEEEVGPLVEHIYELHNIGPSTISDSILEVGWPFSAREEFLLYVFHLQTLGPLQCQTNPEINPQDIKPAASPEDTPELSAFLRNATIPHLVRKRDVPVVQPHRQSPAKILNCTNIDCLQISCAVGRLGGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKIPYKEQPAKLPAGSTAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQDEMTDREQLTSDKTPEA
Protein: Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing) (P48462)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for cell adhesion in non-muscle tissues and in maintenance of muscle attachment. Vital for larval development.
Interaction partners:
- Protein phosphatase 1 regulatory subunit 12B
- LD46604p
- Myosin regulatory light chain sqh
- GH07711p
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- LD24014p
- Serine/threonine-protein phosphatase alpha-2 isoform
- FI19335p1
- WD repeat-containing protein 82
- Nuclear inhibitor of protein phosphatase 1
Sequence:
MGDFDLNVDSLIQRLLEMRSCRTGKQVQMTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPSEKKAKYLYSGMNSSRPTTPQRSAPMLATNKKK
Protein: Uncoordinated protein 79 (G5ECI9)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MATTRAATFSAKIRTLSEFQIRLSTNQQPPSNAEIITTLRYFQQTLIGFLKDFPSTQTNYCERFSSDAARWNLYPNLNYSALYYAIVNLLDVFPLITSQPQAIGEAILDTIKALMIFLERESLEQLPLLLASQLGIFPRELDKQIVHLLADCVFPFAINDETYVKYSVPGVLMLVLQQTHDPSLHTWIVESAMNCSQGVYQDLLQVIAKGTCESRVAAANLLFHYWPFPNPQILHRKTIQYRVHAWRTVQCQSTGCSDKTASVKRCYDPVICADVADTSPPIFLCRKCAEQVTGERKVITQHIAQPMPASNATCQRQECQSQSRLAVTICCSHECTRGHNHVPMRLCMDCSTLVHEEGTIKHLQHQGSGVVWSTDDQWPTVESIVKLLRETTMFEGNEGEGKKPKWLRQLDGGTSMGKEIDKMADERRMLSRFGVWLMAGLCPPNESADPRAIGYIMQNVFEWFSTTALLPNDSMGASLEQLKTDFVSDWINIGMRVHNAVFISSLCGECEEQDGRPVIDRIKEGLGRLLALMPYDVISLETWSRVMPRWLEAIVNDCTEDNQPELKILLCKIFEPDLCPLPFETKEVYGFMTGRIGGDDYDEMFNALQWIHQLSRLDITIPLNMILEHFNRCLQKLRTIEIPPLSENDLEEEEMSVHVVLVDTLVLQMKLNDSDRSMTPALTDKLFECMQLLVSIPIRAVPHSCHDPELDGFADCQQCQQTAFVHQMVMNITQKVCPKREVAIITTVDEDPNYDEQTTDTPTGPGSTLLSPLTESGSKGTSPGTSAPSRPFPEHLQAQTMCVAQACEAEEEVEECEFVGILPCEEMEVAMAEAVTHDNVLETGQVVTSTTVHPSIKGQIIQTPQTPVQKQPPSDFWVTSVGRFRFSFEQLPSQLKMIHSLLSCLDEAVEPDVEFFVMSSMKYLCLHCEALSNARREHRGFLIWTQENQMVPKLWERLRSDYIQVGELATHLLLHAMTLPCGEEMFWKMVHRDFTSPQWNVRFDAVGKAYVMAQMIKTAPVKANKVVQTCLAAVFYHFIASLHDPNPSVAQRAIIALRAMPRHTLKLMCMCFESQFDHCIVDRPLIIHAITMMSILLPDQTTLTFDFFIQRFETLVLESQLSSQTEENIFVQDLMHTDPMSELYQRKVSKARSAIENASTARSIVRHLKQYDGMKHQLAHLPSDPANVAVNDDVSSPNSSVTANYGHGGYGRLREFTDEESNMCLLFNRVVDMENPERHTVYLVVSLFVTFLSNKNSTPTDEKANAKKQSLVFRHFNTLLGYSSTEKCFTIPPARLRKAAVCNAFISGLPEILDMNLHTGNQLLPTVAQLLIHLPSPQKLASDQNVTNYSLALLTQHTRHLWLQSLILILYKYRFDQLPVSEYIVRLIGIVVKTLQNQVHECSDAADQSAEIDTWDEIEDDDVARAELIRPESLTVTTIQEATPAAEGMVHIGAVCVMQPTIVEPEGLAPEPLIARKRSTAVQEVRRKKSAIEVVKKSCTLRCGHCNEAIEMFDEETISLCLIALETFLHREPSMAAPILFKILYTVTRLIDTPMYPWHSTEMFVPANSRSVAKQMLRVSLHHLSTSAICLQLFDTKIPRPDAFWSVVALSLADFPELSPVYFIQILMEDLEESWPGSVKLIMKNLAFYIVEIPTDMYNNPWKDLVGHLETFFKRYHSAISADNGITPTRAEIENVIIVMTHVFKVQTFSSSKSPVTLVEAFARWLSESLHSADVSLESLLGVCTACNRALIRERDKQCITRALVTELMQAIKFKVKLHESNYVTIANMILQDAGEDIEVPLLDDQFNTAASEAIRPFLFEVLDFIADLHVIAKLKKESNSDALGGDLKVKLAEAIAVEMSRSNARDCRTVIRFIPWLMSPPSVTQAAPSAFADSVTNVRVLSWLLLGALHANHSCLPVPIECSQHMADYIHFVLAGFADQSKQSVVHMSALFHAFHLCQLWTVYCERAATYSSTTAFAHLVDFWARVTPAILQLLSHSKVLADMVNLHFLNTIQALQQVNSALLCQLYSMWAPILTAYHSQIPNQLRMKLDSCQNQPSLEAPLVTEWLKKVRYKISQVELQTSAASPYYTV
Protein: Ubiquitin-conjugating enzyme E2 D2B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D2B) (Ubiquitin carrier protein D2B) (Ubiquitin-conjugating enzyme E2(17)KB 2B) (Ubiquitin-conjugating enzyme E2-17 kDa 2B) (Ubiquitin-protein ligase D2B) (P70711)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection Plays a role in early maturation of the testis.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 D1
- Ubiquitin-conjugating enzyme E2 D3
- E3 ubiquitin-protein ligase TRIP12
- Ubiquitin conjugating enzyme E2 V1 like 1
- Polyubiquitin-C
- Uncharacterized protein
- Breast cancer type 1 susceptibility protein homolog
- E3 ubiquitin-protein ligase RBX1
- STIP1 homology and U-Box containing protein 1, isoform CRA_b.
- Ubiquitin-ribosomal protein eL40 fusion protein
Sequence:
MALKRIHKELNDLAQDPPAQCSAGPVGEDMFHWQATIMGPNDSPYQGGAFFLTIDFPTEYPFKPPKVEFTTRIYHPNVNSNGSICLDILRSQWSPALTISKVLLSISSLLCDPNPDDPLVPEIAQIYKTDRDKYNRTAREWTQKYAM
Protein: Ras-related protein Rab-27A (Rab-27) (EC 3.6.5.2) (GTP-binding protein Ram) (P51159)
Organism: Homo sapiens (Human)
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Melanosome {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}. Late endosome {ECO:0000269|PubMed:15548590, ECO:0000269|PubMed:30771381}. Lysosome {ECO:0000269|PubMed:15548590}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). Localizes to endosomal exocytic vesicles (PubMed:17237785). {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065, ECO:0000269|PubMed:17237785}.
Interaction partners:
- Synaptotagmin-like protein 4
- Rab effector MyRIP
- Unconventional myosin-Va
- Protein unc-13 homolog D
- Melanophilin
- Synaptotagmin-like protein 2
- Synaptotagmin-like protein 1
- Exophilin-5
- Synaptotagmin-like protein 3
- Rabphilin-3A
Sequence:
MSDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCVDKSWIPEGVVRSNGHASTDQLSEEKEKGACGC
Protein: Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1) (Q7L0Q8)
Organism: Homo sapiens (Human)
Function: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Lipid-anchor {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Cytoplasmic side {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Golgi apparatus membrane {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Lipid-anchor {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Cell junction, focal adhesion {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Cell projection, podosome {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Note=Localizes to podosomes in SRC-transformed cells. {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}.
Interaction partners:
- Serine/threonine-protein kinase PAK 4
- Serine/threonine-protein kinase PAK 1
- Cytoplasmic protein NCK2
- Growth factor receptor-bound protein 2
- Rho GTPase-activating protein 30
- SH2/SH3 adapter protein NCK1
- Proto-oncogene tyrosine-protein kinase Src
- Intersectin-2
- Serine/threonine-protein kinase PAK 2
- Protein-tyrosine kinase 2-beta
Sequence:
MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCFV
Protein: Serine carboxypeptidase-like 34 (EC 3.4.16.-) (Q0WPR4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable carboxypeptidase.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Membrane-associated progesterone-binding protein 4
- Prolyl carboxypeptidase like protein
- Alpha/beta-Hydrolases superfamily protein
- Proteasome subunit alpha type-5-B
- Aspartyl protease APCB1
- At3g52500
- At5g65760
- Alpha/beta-Hydrolases superfamily protein
- Aspartyl protease AED3
- Prolyl endopeptidase
Sequence:
MGSHSVEFSVLVLFLVSFLLGSTSAEKLCSDNDGDNGCFRSRVLAAQRADRVKELPGQPPVKFRQYAGYVTVNETHGRALFYWFFEATQNPSKKPVLLWLNGGPGCSSIGFGAAEELGPFFPQNSSQPKLKLNPYSWNKAANLLFLESPVGVGFSYTNTSRDIKQLGDTVTARDSYNFLVNWFKRFPQYKSHDFYIAGESYAGHYVPQLSELIYKENKIASKKDFINLKGLMIGNALLDDETDQKGMIEYAWDHAVISDALYEKVNKNCDFKQKLVTKECNDALDEYFDVYKILDMYSLYAPKCVPTSTNSSTSHSVAGNRPLPAFRSILRPRLISHNEGWRRMAAGYDPCASEYTEKYMNRKDVQEALHANVTNISYPWTHCSDTVSFWSDAPASMLPTLRTLVSAGLRVWVFSGDTDGRIPVTATRYSLKKLGLKIVQDWTPWYTKLQVGGWTVEYDGLMFVTVRGAGHQVPTFKPREALQLIHHFLGNKKLPTFPF
Protein: Paired box 2 (A0A0G2JZ47)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKREEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH