wanglab/gogpt-training-data huggingface dataset:
Protein: Anti-sigma factor antagonist (O07728)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Multidomain regulatory protein Rv1364c
- Anti-sigma-F factor RsbW
- Conserved protein
- Probable conserved membrane protein
- Anti-sigma-F factor antagonist RsfB
- Uncharacterized protein Rv1354c
- GFO/IDH/MocA-like oxidoreductase domain-containing protein
- Uncharacterized protein Rv2079
- RNA polymerase sigma factor SigF
- Methyltransferase domain-containing protein
Sequence:
MRTVAIGPGAGPSSTRPSSQPSDLHSGLRAVTECTGSAVVVHVGGDIDASNEVAWQRLVSKSAAIAIAPGPFVIDIRDLDFMGSCAYAVLAQESVRCRRRGVNMRLVSNQPIVARTIAACGLRRLIPLYATVETALAPPPSAH
Protein: Inositol polyphosphate 5-phosphatase E (EC 3.1.3.36) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV) (Q9VTW2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2, and phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) to phosphatidylinositol 4-phosphate (PI-4-P). By controlling the phosphoinositide composition of the cilia membrane of auditory receptor neurons, regulates the cilia localization of ktub and consequently the transient receptor potential channels iav and nompC.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:26723017}. Note=Localized to the transition zone, which marks the boundary between the plasma membrane and the ciliary membrane. {ECO:0000269|PubMed:26723017}.
Interaction partners:
- Phosphatidylinositol-3-phosphatase SAC1
- EG:86E4.5 protein
- Phosphatidylinositol 4-kinase alpha
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Phosphatidylinositol 4-kinase beta
- phosphoinositide 5-phosphatase
- Phosphatidylinositol 5-phosphate 4-kinase, isoform A
- phosphatidylinositol-3,4-bisphosphate 4-phosphatase
- Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform E
- Pi3K21B, isoform B
Sequence:
MQHSSAGSEERITSSTSSPRSGHKTASSLFGLLSKRPSKVEPHPVTPESPRLQQRPVSACGQYDVSFAKCNADTSANHVNNNGSTLKSQTLPLEKSHSGLISFHRRAKPSSSKGKNHSHRHSTDAGSQSDGGADVVMRRKSPKHRSPNHNRFSHQFSLCCKAEKKPMTPPVTVRYNSIPDSNSVLRRDNLSLSWSMVDNNSGSLHSSEGSSHRPRPSSECASAPESPVASKTFFAHCSPAAASASVARSESLQNRSPIRPMAVSACRSRLRLKLYPPGQELPPLQAATEPGDIKRATTPQHMSSPNIATQPDGIEHIEEQPGVRFMSHENMTLQRQGSGSNLARQTLMAAHALNLIPADNARERSYLDGRLGSTSLLGPSELSRVLPQKEITVFVGTWNMNGHSPPKQLNDFVLPANVEHVPDIVVMGTQESTPDRFEWEVTIQETLGPSHVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASMSVRTGSAFRTKGAVAISFCLFGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLPRNLPNQRHKNKDVTQNFDNVFWCGDLNFRLGEPREKLLEWIQNTKFPLPSHLPHGYMHTDQLTSVLADGAAFRGFMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQGLVIRRQTLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVWALFRTLIRAGTDAIPLAAGLFSRDIYLEGMRRRLNNQYSGASAVCVLQ
Protein: 5-hydroxytryptamine (Serotonin) receptor 2A, isoform D (RH04788p) (Q6AWQ4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MEMQSYSGRGPSTGTSETATATAAVASASASDTAATFTLRHFNCRLEEADWPGPRQPFIDCEGSHTNSTSYTPSSLPTSKNLIEGPNNTFQCARQAIDEAEHNAFYSCDGESPLSENCTLRLKARLLRWPYEAYEHIRLAINGALSDYASDKLSDSSSCDEGGMVLQCKLGQAHELLLCHLQQLEREPLREVGSAEESFSNDSLLQAFQIELGAERDGLWSFLNLSELMEPDHGFLGIMNVTNTSLDMFLPNLTALNTTSTASTADMATEFAVTKSFLDYSPHGYDFLFLFVVFFIFAGGLGNILVCLAVALDRKLQNVTNYFLFSLAIADLLVSLFVMPMGAIPAFLGYWPLGFTWCNIYVTCDVLACSSSILHMCFISLGRYMGIRNPLGSRHRSTKRLTGIKIAIVWVMAMMVSSSITVLGLVNEKNIMPEPNICVINNRAFFVFGSLVAFYIPMLMMVTTYALTIPLLRKKARFAAEHPESELFRRLGGRFTLRPQHSQQQLQMFSSFSGSNNKFLSMGDGNRNFNTEGEMEEGGAPSRRSGVEPAERPLMQQRTASSRSMGTVSFRNVVNGTSGAAGSGRRTTGTAHSSFRFSGAGIFRHSSSSPASSCHSTSTSRSSSFWRKHGGYPNLMDR
Protein: PH domain-containing protein (G5EER5)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MMNDETRRRRFIYLVGYRQRDREHEVDPRMTQSMISERIQRSQSPVDVSLALSEDSTITITELNNRNGSTFNANSINATPVMRRRRSQMSGVRQRNYRILDQNESKYILQQQSAAAIEEKKGTLLRRKSSKKLIEPLPMIITPPVLMARTQCCAVCYKEKSTGYSVSSRTQSYPLEAMSSVTTDRSTEEETARLSFVSSSTGYSSARSSLRSSDGGDESNNNSAGNRDSAISNTFSLSSQSSARRSALLTKGSLTHLDRIAIELLDTERTYVEDLNAVIKGYMDFLVEDREKLKVTLDAISSLFGCIERIFAFNKQLYNQLDAADLDCVKMSRCFVESSGKFEDYIEYCTNYHRMMSTLYHLQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTHPEELIQVKRAHEVMTSQAARINDEKKKAEHIERVGQLQSTLQKWKADEIQISNLSAYGDLLLEATFRQAGSKTTRLLFLFEEMLLIVKQRGANYVCKDYIMCSNLMLNEWICPEEPLSFQVLSFDNPRAQYVFMASSMEQKRTWMQELKRMMLDHYSVEIPEKTKQLMLSIDNTRIVPFGRPEFAEVSMKNHKKVPKYLEKRRKSVDAKEESNRRRSLSASRLLGGSKTSISEPIKEEQKCTCHMNGGIYNGANPTTSKSIISHPSLTYQQSHPTQSTDPNYCRPPVCRTQSAATIDLNQVHITEPNSAAVMSSRSRYQQARNRRLPPRHNQESRSTSSRRMGEEEIDRTFDQLYEELVSFGDSTKPTVTSNRSQRLRSEAPQSTVTTITVAATPATATLSIAECANTRLRSKSLTRLDEYEAEPISLKPSIERRYSKVDQLKKRSRKYQVNQEPEAADVLRPSVGRFSLTDHEIIIHGEEPYKRSSGRQRTPLTAQQTAELDDYFPSSNSMNSAPQTCSSSATPSLMSIIRQYENA
Protein: Tyrosine-protein phosphatase non-receptor type (EC 3.1.3.48) (Q7ZW17)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|PIRNR:PIRNR000929}.
Interaction partners:
Sequence:
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGREAEKLLTEKGKNGSFLVRESQSHPGDFVLSVRTGDDKTDTSEGKPKVTHVMIRCQHDLKYDVGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAEATDKVKQGFWEEFETLQQQECKLLYSRKEGQRPENKNKNRYKNILPFDHTRVVLTDGDVNEQGSDYINANLIMPDNEAKSNNSKLKRSYIATQGCLQNTISDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDVSALKEYGAMRVRNVKETMAHDYILRELKLSKVGQGNTERTVWQYHFRAWPDHGVPGDPGGVLDFLEEVKLKQEGITGAGPIVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKIKGREYTNIKYSLSDLSGGDQSPLPPCTPTPTCADMRDDSSRVYENVGLMQQQKSHR
Protein: Pro-FMRFamide-related neuropeptide VF [Cleaved into: Neuropeptide NPSF; Neuropeptide RFRP-1; Neuropeptide RFRP-2; Neuropeptide NPVF (Neuropeptide RFRP-3)] (Q9HCQ7)
Organism: Homo sapiens (Human)
Function: Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced analgesia.
Subcellular location: Secreted {ECO:0000305|PubMed:11025660}.
Interaction partners:
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Neuropeptide FF receptor 1
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 3
- Neuropeptide FF receptor 2
- Elongation factor Tu, mitochondrial
- Cytochrome b-c1 complex subunit 7
- KiSS-1 receptor
- Metastasis-suppressor KiSS-1
Sequence:
MEIISSKLFILLTLATSSLLTSNIFCADELVMSNLHSKENYDKYSEPRGYPKGERSLNFEELKDWGPKNVIKMSTPAVNKMPHSFANLPLRFGRNVQEERSAGATANLPLRSGRNMEVSLVRRVPNLPQRFGRTTTAKSVCRMLSDLCQGSMHSPCANDLFYSMTCQHQEIQNPDQKQSRRLLFKKIDDAELKQEK
Protein: RE08173p (Transglutaminase, isoform A (EC 2.3.2.13)) (Q9VLU2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGQKLSCCQKCGDWKWCTSKDNEESTLRIRNANANYFTGIPQGDKTDGASSAVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLGDGSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLGTVGRIPPAYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYKTQKSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWRYNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQSRHAFSRYYLNDNFNDIEFDMELKDDIKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIEPRPEDLLQPNGSHRSSNIIRRRTDVIA
Protein: Quinate/shikimate dehydrogenase (EC 1.1.1.282) (NAD-dependent shikimate 5-dehydrogenase) (P0A6D5)
Organism: Escherichia coli (strain K12)
Function: The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
Interaction partners:
- Shikimate kinase 1
- 3-dehydroquinate synthase
- Shikimate kinase 2
- 3-dehydroquinate dehydratase
- Inner membrane transport protein YdiN
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Chorismate synthase
- Shikimate dehydrogenase
- Inner membrane transport protein YdiM
- Isochorismate synthase MenF
Sequence:
MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
Protein: Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Q69ZK6)
Organism: Mus musculus (Mouse)
Function: Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRASQNISTVHGHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEDKYDCVSRGENPKGKNKHVVTKRRKPEEAEKRLSMKRLRTDNASDASESSDAESSSKRVTETSSSEPMPEYEPKNKVTSKVNGEEGQSQAAEEAGEETLIDTRPPWDQMQEDKNHNEGEKPKSTDSHLQDKMTLRSSEQATVADHNSNDSVLQECNVENQRTVELLPKDRLVSRTPTPKCVTDIKNDTHSERAAQENLNTFGLQTPENMDPNVSDSKHSNAKYLETAKQDCDQSWVSDVVKVDLTQSSVTNAPSGSDKRDTEKERNHYVSYMSSLSAVSVTEDQLHKRSPPPETIKAKLTTSVDTQKAKSSSSPEVVKPKITHSPDSVKSKAAYGNSQAVGERRLANKIEHELSRGSFHPVPTRGSALETTKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFSLHSSSHRTCLNPGTHHPALTPGPHLLAGSTSQTPLPTINTHPLTSGPHHPVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPHKITVHSSPPLTKTLADHHKEELERKAFMEPLRSNASTSVKGDLDLNRSQAGKDCHLHRHFVGPRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGHEVERENYSRVVPSSSSPKSHAIKQDKDVDRSVSEIYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYTEKQNNNLSATANPQTHSFISSLSKPPPLIKHQPESESLVGKIPDHLPHQSASHSVTTFRSDCRSPTHLTVSSTNALRSMPALHRAPVFHPPIHHSLERKESSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQSNFKNSSDQSLTEMWRSNNNLNREKAEWPVEKSSGKSQAAVASVIVRPPSSTKVDSVPSVPLASKDRVCERSSSGANKTDYLKPEAGETGRIILPNVNLESAHVKSEKNFEAVSQGNVPVSVMSAVNVVSTTKADVFTSAATTTSVSSLSSAETSYSLSNTISASTPFECTSSKSVVSQAVAQAKDCTVSTAVPGTLACSKTGSAVQPGSGFSGTTDFIHLKKHKAALAAAQFKNSSVSEAELNTVRNQTVAASLPLDSTMTCTASNKAISVGNGPAAQSSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSNDIENRADGRVAVDKYGRDEKVSRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEVEEDSKPNGVLSRSAKDKSKLKLQNSNSAGVPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEESTHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWTHENYEDDEVDVETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNVHWVCRKCGFVACLDCYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMLTQIIPGSVLTDLLDAMHILREKYGIKSHCHCTNRQNLQGGNVPTMNGVSQVLQNVLHHSNKTSVSLPESQQQNSPQKSQTNGNSSPGSASTDSRLTPPESQSPLHWLADLAEQKSREEKQENKEFTLEREIKEDGDQDASDSPNGSTSPPASQSNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGTSSGKGGRTMPNILDDIIASVVENKIPPNKTSKINIKSEPNEEPKESSLPATDESNKSYRDIPHSWICDQHILWLKDYKNSNNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIVSNANVKEFWDGFEEVSKRQKNKGGETVVLKLKDCPSGEDFKAMMPTRYEDFLRCLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVAAAKDHDIGTTNLHIEASDVVNVLVYVGIAKGNGVLSKAGILKKFEEEELDDVLRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNRKLRQRLLEEYGVRACTLIQFLGDAIVLPAGTLHQVQNFHSCVQVTEDFVSPEHLVQSFHLTQELRLLKEEINYDDKLQVKNILYHAVKEMVRALKMHEDEVEDMEDT
Protein: Early growth response protein 4 (EGR-4) (AT133) (Q05215)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required for mitogenesis and differentiation (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- NGFI-A-binding protein 1
- NGFI-A-binding protein 2
- E3 SUMO-protein ligase EGR2
- Neuronal PAS domain-containing protein 4
Sequence:
MAVARGVGSPEPAPPQLYKWGGCGLGEPGSALERRGAAARGRCGRARAPRLPDSFPRGECPKPGARAPRSVRCGEPLPPASPPPARPQAQRARPRAPHSRRRAMLHLSEFSEPDALLVKSTEGCCAEPSAELPRLPARDAPAATGYPGAGDFLSWALNSCGASGDLADSCFLEGPAPTPPPGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAPFPEAFWEASPCAGAPSQCLYEPQLSPPDVKPGLRAPPASPALDAVSAFKGPYAPWELLSVGAPGNCGSQGDYQAAPEARFPVIGTKIEDLLSISCPAELPAVPANRLYPSGAYDAFPLAPGDLGEGAEGLPGLLTPPSGEGGSSGDGGEFLASTQPQLSPLGLRSAAAADFPKPLVADIPGSSGVAAPPVPPPPPTPFPQAKARRKGRRGGKCSTRCFCPRPHAKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFASL
Protein: Protein transport protein Sec24D (D5LMH4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004397}.
Interaction partners:
Sequence:
MSQQGYVATPPYSQAQAGMGGYAAGFGNPPPQSHYGAYGSPTQGYSAPPPGVLKPPASSPSGMPPPPVSSQYGTNIQQNGAHPHSFPPPVSSSPSMSPYGQPPPTAFRSMAQAPPPTQQLTNQMSAMNIAGYGQRPVQSPSNSAPAHFQTSPPPPVMGHPPLSPPGQQPSPLGSPPPMATMGSMPAPPMGMSGPPGPVVHQPPHGPQGYPQQPGSPIAGPYGAQMAGPQGQGPQTGAFPGGFAGGPAQMAGPPQKKLDPDSIPSTTQMMRMTRLKRRQVYVTNTRGQVPPLVTSKFTVQDQGNASPRFMRCTTYSFPCTADLAKQCKVPLAAIIKPFAAVPKNETPLYVVNHGETGPIRCNRCKAYMCPYMQFIDGGRRFQCSFCSCVNEVPVHYFQHLDHMGRRMDLYERPELSLGSYEFAATLDYCKNNKPPNPPAYIFMIDVSYNNIKSGLVRLICEELKTLLDRLPKEEGAESSSIKVGFVTYNKILHFYNVKSALAQPQMMVVSDTAEMFVPLLDGFLVNFQESRAVINNLLDQIPDMFADTNESETVFAPVIQAGLEALKAAECSGKLFIFHSSIPTAEAPGKLKNRDDKKLVGTEKEKTLFQPQRGVYEQLTKDCVAQGCCVDLFLFPNQYVDIATMGDVPSHTGGSIYKYSNFQVEVNGQQFLSDLSRDVEKSIGFDAIMRVRTGTGFRATDFFGAVYMNNTTDVEMAAVDCDKAVTVEFKHDDTLSEESGAVMQCALLYTTIGGQRRLRIHNLSLNCSSQLSELYKSCETDALINFFAKSAYRAMLNQPMKTVREILVNQTAHMLACYRKNCASPSAVSQLILPDAMKVFPVYMNSLLKTPALVSSTELSTDDRAFHRFMVNAMGVEETQVLLYPRLIPLHTMDVSSESLPAAVRCSEERLNESGMFLLENGLSMFLWLGQACSPDLIQNLFNVPSFGHLPAEGTSLPVLDNAHSRKLHSIISRISQQRAASMKLLIVKQKDRAEMSIRQLLVEDKGLHGGASYMDFLCFVHREIRQLLT
Protein: BcDNA.GH03693 (Ephexin) (Ephexin, isoform B) (Ephexin, isoform C) (Q9Y150)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSALNRSNGQRLSCSGSLSSSGHPADPVTLPRKRRPRARGEVGVTCQGSSTVYLNGPVSAEPIRPAPEPIYQNEAAAISQRCSYSHQRAQLLTSMRVTVAEGAENDAKVTMEVSTFVDDSDHYYETLSPLGNKRHSTQLVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYNDSGVDMRNHRLPKPPPPQNQVYEFVRKFKDFISSKKSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKNGKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPEIHGSGELDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERELDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEASPSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQAFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAKLTFGKRLTKISIYAFLFSDLLLLCKRRGESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCPSVSDQQRWLQAMRPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSAHVRARNLKQRHRLLTFTATYLESQKSK
Protein: NMDA receptor 2, isoform F (NMDA receptor subunit 2-3) (Q6IWN7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}.
Interaction partners:
Sequence:
MMPSRVKLKRGTDGPTPTPTPMPTTMRKHTPIATLNTASCQHNSTTSRRKRILTPPSGPISLLLLTVLTLLILDTRSCQGLRLTNGGGSLSKGAAANKEQLNIGLIAPHTNFGKREYLRSINNAVTGLTKTRGAKLTFLKDYSFEQKNIHFDMMSLTPSPTAILSTLCKEFLRVNVSAILYMMNNEQFGHSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDLMELVNSEARVMLLYATQTEAITILRAAEEMKLTGENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLEKVMDKHGIKAPQLRLASSSDLLNHHHLKERPPLLGNLSLAASAQDLYRW
Protein: Protein reprimo (Q9JJ72)
Organism: Mus musculus (Mouse)
Function: May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10930422}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MNSVLGNQTDVAGLFLVNSSEALERAVRCCTQASVVTDDGFAEGGPDERSLYIMRVVQIAVMCVLSLTVVFGIFFLGCNLLIKSEGMINFLVKDRRPSKEVEAVVVGPY
Protein: Popeye domain-containing protein 3 (Popeye protein 3) (Q9ES81)
Organism: Mus musculus (Mouse)
Function: May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding. May play a role in the regulation of KCNK2-mediated current amplitude (By similarity).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MEKNSSLWKSLVTEHPLCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLSSAVWAWVDICAADIFSWNFVLFVICFMQFVHIAYQVHSITFARDFHVLYSSLFKPLGIPLPVFRTIALSSEVVSLEKEHCYAMQGKTSIDRLSVLISGRIRVTVDGEFLHYISPFQFLDSPEWDSLRPTEEGIFQVTLTADTDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKKHHYDIRLPNYYHMSTPDLSRSPLTEQFRNSRQHCNK
Protein: Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E2RUH1)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MAKKGCFYFHQVISLFAFAFGVNVCMGFTTNRFRRSEEWDEGPISVLSDSPWISTSGSCKNRCFELQEAEPPGCRCDNLCKSYNSCCFDFDELCLKTARGWECTKDRCGETRNDDNACHCSEDCLSRGDCCTNYQVVCKGETHWVDDDCEEIKTPECPAGFVRPPLIIFSVDGFRASYMKKGNKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFSLRGREKFNHRWWGGQPIWITAAKQGVKAGTFFWSVVIPHERRILTILQWLTLPDNERPYVYAFYSEQPDAAGHRYGPFNSEIYTTERALKHIEIWHCYTVPAAPLTRCLETAIVSVQTWVSYARVFLAY
Protein: Diterpene cyclase DtcycA (Cembrene C synthase) (EC 4.2.3.148) (Nephthenol synthase) (EC 4.2.3.149) (M1V9Q0)
Organism: Streptomyces sp
Function: Diterpene cyclases that can form multiple diterpene products.
Interaction partners:
Sequence:
MTDPAVTPLAFSIPQLYCPFPTAIHPEVDTLTRAGMDFMTHHGFCNTEADRLVVANIDAGAIVARWYPNPDFPVDRLQMVTDFLYLYFLIDDLRFEVINSDTGLAGPIALFAQHLDLWEYPQAHRREELDLFHQAIHDLASRMAELTTPTKAARMRRSINGWFLALLREIALFNDDHAVMAEEYLPIRVVTVASRLMIDVNGFICPAEVPGDEWYSLKVQAAAEAAMSVCLYDNELYSAGKEQWLKSRATAHDRRPRNLVALIQAQTGGSTEHALQEVAEYRNRTVCLYLNLRSQLEKTASPALLAYLSVLDGVISGNLDAHATSSRYHNPDGHHPHAIAFTPLRTTDECSARAHTPIAPPIAWWWEQLDQ
Protein: Large ribosomal subunit protein uL10c (50S ribosomal protein L10, chloroplastic) (CL10) (Q9FY50)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This protein binds directly to 23S ribosomal RNA.
Subcellular location: Plastid, chloroplast {ECO:0000250}.
Interaction partners:
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL24c
- Large ribosomal subunit protein uL6c
- Small ribosomal subunit protein uS13c
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein bL28c
- Small ribosomal subunit protein bS1c
- Large ribosomal subunit protein eL24y
Sequence:
MEVALLSFSSSLSPLCHQRISTLTPKTSNSPNYPRLPVIRSAVSRNKKEETVEAVKSHLENCHLLAAINYKGLTVKQFQDLRRTLPDTTKLIVAKNTLVFKAIEGTKWEALKPCMKGMNAWLFVQTDEIPSAIKPYRSFQKERKLENNDFAGAVFEGKFYAPDNFKVLETMPTRAEVYAKMLGALQSPAINLVTTLQAPAREVIMVLMAYIKKLEDESNA
Protein: Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Glutamine synthetase I beta) (GSI beta) (P15106)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Function: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia (By similarity). Complements L-glutamine auxotrophy of an E.coli glnA mutant.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P9WN39}.
Interaction partners:
- Glutamate synthase large subunit
- Glutamine synthetase
- assimilatory sulfite reductase
- Glutamate dehydrogenase
- Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme
- Uncharacterized protein
- Glutamate synthase small chain
- Bifunctional uridylyltransferase/uridylyl-removing enzyme
- Glutamate synthase small subunit
- Nitrite reductase small subunit
Sequence:
MFQNADDVKKFIADEDVKFVDVRFCDLPGVMQHFTLPATAFDPDAEQAFDGSSIRGFQAIHESDMSLRPDLSTARVDPFRRDKTLNINFFIHDPITGEQYSRDPRNVAKKAEAYLASTGIADTAFFGPEAEFYVFDSVRFATRENESFYHIDSEAGAWNTGALEDNRGYKVRYKGGYFPVPPVDHFADLRAEISLELERSGLQVERQHHEVGTAGQAEINYKFNTLLAAADDLQLFKYIVKNVAWKNGKTATFMPKPIFGDNGSGMHVHQSLWSGGEPLFYDEQGYAGLSDTARYYIGGILKHAPSLLAFTNPTVNSYHRLVPGFEAPVNLVYSQRNRSAAMRIPITGSNPKAKRVEFRAPDASGNPYLAFSALLLAGLDGIKNKIEPAEPIDKDLYELAPEEHANVAQVPTSLGAVLDRLEADHEFLLQGDVFTPDLIETWIDFKRANEIAPLQLRPHPHEFEMYFDV
Protein: AAA-ATPase At3g50940 (EC 3.6.1.-) (Q147F9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Glutaminyl-peptide cyclotransferase
- Multiple organellar RNA editing factor 9, chloroplastic
- Multiple organellar RNA editing factor 1, mitochondrial
Sequence:
MSSSSESHLATAKTALTAVASVAAAAILARSVVQDYMPNEVHEYISHGFRRFFSYFSYQMTAVIEEFGGFEHNQVFEAAEAYLSTKISNSTRRIKVNKLEKQSNYSVTVERDEEVVDIFDGVKLSWILVCRHVDKKDFRNPRDLNSTLKSEVRSYELSFRKKFKNMVLESYLPFVVEQAASIKQKFKTLKIFTVDSYSVEWTSVTLDHPSTFRTLALDPEVKKNLVEDLDRFVQRKGFYGRVGKAWKRGYLLYGPPGTGKSSLIAAIANHLNFDIYDLDLTSLNNNAELRRLLMSTANRSILVVEDIDCSIELKDRSTDQENNDPLHKTVTLSGLLNFVDGLWSSCGNERIIVFTTNYREKLDPALLRPGRMDMHIHMSYCTPAAFKVLASNYLEIQDHILFEQIEEFIREIEVTPAEVAEQLMRSDSVDKVLQGLVEFLKAKKQIDNSKA
Protein: Pescadillo homolog (Q38EE3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|HAMAP-Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03028}.
Interaction partners:
- rRNA processing protein, putative
- Ribosome biogenesis protein BOP1 homolog
- Nucleolar complex protein 2
- NLE domain-containing protein
- Nucleolar GTP-binding protein 1
- Ribosome biogenesis protein NOP53
- Ribosome biogenesis protein NSA2 homolog
- Ribosome assembly factor mrt4
- Ribosome biogenesis protein NSA1
- RNA processing factor 1, putative
Sequence:
MHRKQAWSKRVKKERQKKKYLTRMQATRLLQVDSIHFRRLCILKGIYPRALNRSKQKQSGNDKQYYLAREIKWLVRDHLADRMMAFRAWEKKVRRAEAMRLTEDLKVLHSNKVKPKYSLVATIKERYPYFADAVRDIDDAMSMIALYAFLSPEVASESTIETHHTLTSGLHRRARETCERWNSYVERAQALSKGFISIKGYYFEAIVRGERVRWLCPHEYAHKFPAGVQQYIMISFLEFYLELMRFVLFKLERDLAEKQKAEEEEPNLNAENFDTTNKETVQGLGGTVGQVAKRVELMDEELRKVRRVFEGLSFYISREVPHKHAALVIKACGGRVATGYVAENITHFVVDRPALPPGFEKDDRIEYVQPQYLFDCLNARLLLPPNGYRIGEELPPHVSPFTVAITNSTEDIAAVEEARRDHPKIVSYVPKRVHEIRKLINPQYTPTDPDGKAAELLLEEESDEENVAAQELDRDDDVQLSGDELQEARRRPKWEDEQVTESVERTKLSALKVRQQRELNLMNAPTNEAVARRRLAQQKAKEARKQQETDEHRLRRKLADVKRQEVATRKMQLQVARKKAARYYKMVNGVVQGNERREKMLTAKAKQLSEGRISAAKDGSGLVNNKLEARRAKAEAAGKKLKEKKPSNPYSKLPKWVR