wanglab/gogpt-training-data huggingface dataset:
Protein: ATP-sensitive inward rectifier potassium channel 11 (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11) (G3I1T3)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- ATP-sensitive inward rectifier potassium channel 8
- Rap guanine nucleotide exchange factor 4
- Rap guanine nucleotide exchange factor 3
Sequence:
VDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPNRLPLFDAIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSFPNLLCFPTDIGLIPVKSSPEEPLKWQYVDQFVSESGGVRGGLGSPGNRTTKEKKVFISLVGSRGLGCSVSSGPIQKPGIFISHVKPGSLSAEVGLETGDQIVEVNGIDFSNLDHKEAVNVLKSSRSLTISIVAGAGRELFMTDRERLEEARQRELQRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEEIMEEEEKFKKQWEEDWGSKEQLILPKTITAEVHPTPLRKPKYDQGVEAKLEPADHLDGNTEKRGPQKGAEKKKAKHDSLQDLRKNKKELEFEQKLYKEKEEMLEKEKQLKINRLAQEVSETEREDLEESEKTQYWVERLCQTRLQQISSAENEIAETFCPSPKPPRGPGVSTISKPVMVHQEPNFIYRPAVKSEVLLVFVMCLSGFYILKPFLCFQDFRKYEEGFDPYSMFSPEQIAGKDVRLLRIKKEGSLDLALEGGVDSPVGKVVVSAVYEGGAAERHGGVVKGDEIMAINGKIVTDYTLAEAEAALQKAWNQGGDLLLKSGERAQPDSILESRWGRQRSQVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFLAAVTSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQARKDMQSPQGARAIWRALCHAFGRRLILSSTFRILADLLGFAGPLCIFGIVDHLGKEHHVFQPKTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQASKYQAVPLKVVNRKRPAREEVQDLLGPLQRLAPSMDGDADNFCVQLLPSIATGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSIPERETAAGSDIRSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKKVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAPILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKASEPSQGLPRAMSSRDGLLLDEEEEEEEAAESEEDDNLSSVLHQRAKIPWKACTKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSVLVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRLEAGGVSVCRSALIQEAGRIDIYSTDPHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHGELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHALLKTEAENYEGLLGHSAVTSHTCAHPRSQCCDLPHLCTPQGHSVPLLLCFQIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSYSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATHRVHTILSADLVMVLKRGAILEFDKPETLLSQKDSVFASFVRADKRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLLPFSHGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITLRHGRLCFMLRVGDLRKSMIISATIHMQVVPLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEKPWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLLDALTLASTRGPLRKRSVAVAKAKPKFSISPDSLS
Protein: Beta-3-glucosyltransferase a (EC 2.4.1.122) (A0A068F9P7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00037847}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00037847}. Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
- Beta 3-glucosyltransferase b.
- Furry homolog a
- Furry homolog b
- ADAM metallopeptidase with thrombospondin type 1 motif, 9.
Sequence:
MLSIKCQNGYSVTQYFFLWSLVAFITAKGDEVENPAKVHGTDKPSSGSQLDLREVVFVIQSQRNSFHVRQAEKLRKDLLLQTQTLQESPPVILLLHTLSDNEGDWSILPLLPRLSSQFGKNSSWIMFLEEDTRVKLQKLHEVLKKFDRRKEWFLGKPLHDEESTIIHHYAFSENPTAFEYPDFSAGWALSIPLINRLASKIEEEPLKSDFTIDLKHEVALYIWEDGKGPRLTGVPELCTLAEHNKRAQSCATTVSSHSPLCGEPVKIENIFVAVKTCKKFHSDRVPVVKKTWGKQASLLEYYSDYADPSIPTINLGVPNTERGHCGKTFAILRRFLSSHVPRTDWLLIVDDDTLISLPRLQALLSCYESSEPLCLGERYGYGLGQGGYSYITGGGGMLFSREAVVQLLSSGCNCYSNDAPDDMVLGMCLNSLRVPVTHSPLFHQARPEDYARDFLSHQTPISFHKHWNIDPIAVFNKWLKNEKHTEGLQKSTKEEL
Protein: Protein SENESCENCE-ASSOCIATED GENE 21, mitochondrial (Late embryogenesis abundant like 5) (AtLEA5) (Late embryogenis abundant protein 38) (Q93WF6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates tolerance to oxidative stresses (e.g. hydrogen peroxide H(2)O(2), diamide, menadione and tert-butyl hydroperoxide) by minimizing the negative effects of oxidation and monitoring photosynthesis during stress. Promotes root development. Prevents premature aging (e.g. senescence and flowering). Involved in resistance against compatible pathogens such as Botrytis cinerea and Pseudomonas syringae pv. tomato.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:21736589, ECO:0000269|PubMed:25005920}.
Interaction partners:
- Late embryogenesis abundant protein 6
- Senescence associated gene 20
- Senescence-associated protein 13
- Late embryogenesis abundant protein 31
- Late embryogenesis abundant protein 3
- Senescence-specific cysteine protease SAG12
- Probable desiccation-related protein LEA14
- At1g71190
- Late embryogenesis abundant
- Late embryogenesis abundant protein 18
Sequence:
MARSISNVKIVSAFVSRELSNAIFRRGYAATAAQGSVSSGGRSGAVASAVMKKKGVEESTQKISWVPDPKTGYYRPETGSNEIDAAELRAALLNNKQ
Protein: Proteasome subunit beta (Q57X95)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU004203}. Nucleus {ECO:0000256|RuleBase:RU004203}.
Interaction partners:
- Proteasome subunit beta
- Proteasome regulatory non-ATP-ase subunit 10
- Protease regulatory ATPase subunit 4
- Proteasome subunit alpha type
- Proteasome alpha 7 subunit
- Proteasome subunit beta
- Proteasome regulatory ATPase subunit 1
- Proteasome subunit alpha type
- Proteasome regulatory non-ATP-ase subunit 9
- Proteasome subunit alpha type
Sequence:
MIEDFSEHHVGEANTLQHHGYSRKLGNSVLTLPLRQGAKGHPQHWSPYTDNGGTIAAIAGSNYVVLGADTRLNGDFCIHTRSDTSKLFKLTDRIFLASSGMQADRLQLQQMLKYRIQWYQYNNGGKVPSTKAIAKLTSTMLYQRRFFPYYTFNMIVGIDEKGAGVCYSYDPVGSTEPFRYGTCGSASSFVEPLLDCLLTRQHMVTQAPADLTMEEALGMLKNAFTGAAERDIFTGDTVCFHIVTADGVGTEMFELRKD
Protein: ZZ-type domain-containing protein (Q4GZB7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDGSECFLVTPTRWGLMLEYEREDAVALLRQKLAFFSSDSLTLTEREDVLLSSGAESSKTDSLLIYGSVALVRKEAFLWFLRVIRLTLVEDMASQVVICPQVGDAVPNLLLPPLWETGQTKSFRRWSVVYWAMRCGILRGIKKRYELTQLYLDQIVSIGAGGDDFDVREEEEAAFLQEKLFHNAHQELRESVLEAKNAPFDIYHSACNEERINLSFVVSNVPTLIVVWASWDGASLDWLRKNIFNREVTCSCDPVPRPTFVADLKIRDPWLRVVREFTSIPNGEANQPVEEVSGIAKCAQIVLISVDEEQGAAVGCLKGLIDGIDGWKSPIVPLMPLWSGPKGMLSELSSALGFSRLPYFMAVQNTRVETAKGDAKQFPRICYVTPNGQGEVPPTQSCTEGNTAELGECGMNSPDWHLVDKGERQRVTGEIERFLLSTDAPLRFHARVDKTYHSLGTPTLASSESHQPDVSSFVSLSGTISSLDLAKLKNALRVFAGVRNSAVNLNVIKPSCPLLVELNPATPTKYIRGVQRCVTCSECHKDILIDKEYHFRCIQCSQVNGTLCKICFEGAKHPAHHILLRMNVETPTTVELLWGPSNVAPLELFRGVLVTNKRNTHIGVYCNLCAQLVRGRRWKCAMCYDFDICNGCIEENCMKFSDAGEVSFVVSDGVGHGQKNTLSSSYHTKDHMFLCVRHACGSAGDACLRPVMEPNAVKLLLEG
Protein: M-phase inducer phosphatase 1-B (EC 3.1.3.48) (P30309)
Organism: Xenopus laevis (African clawed frog)
Function: This protein functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It may directly dephosphorylate p34(cdc2) and activate the p34(cdc2) kinase activity.
Interaction partners:
Sequence:
MAESHIMSSEAPPKTNTGLNFRTNCRMVLNLLREKDCSVTFSPEQPLTPVTDLAVGFSNLSTFSGETPKRCLDLSNLGDETAPLPTESPDRISSGKVESPKAQFVQFDGLFTPDLGWKAKKCPRGNMNSVLPRLLCSTPSFKKTSGGQRSVSNKENEGELFKSPNCKPVALLLPQEVVDSQFSPTPENKVDISLDEDCEMNILGSPISADPPCLDGAHDDIKMQNLDGFADFFSVDEEEMENPPGAVGNLSSSMAILLSGPLLNQDIEVSNVNNISLNRSRLYRSPSMPEKLDRPMLKRPVRPLDSETPVRVKRRRSTSSSLQPQEENFQPQRRGTSLKKTLSLCDVDISTVLDEDCGHRQLIGDFTKVYALPTVTGRHQDLRYITGETLAALIHGDFSSLVEKIFIIDCRYPYEYDGGHIKGALNLHRQEEVTDYFLKQPLTPTMAQKRLIIIFHCEFSSERGPKMCRFLREEDRARNEYPSLYYPELYLLKGGYKDFFPEYKELCEPQSYCPMHHQDFREELLKFRTKCKTSVGDRKRREQIARIMKL
Protein: Nuclease (Q84J48)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein BYPASS1-LIKE
- At4g27652
- At3g04640
- Protein ROH1D
- At1g49000
- ARP protein
- L-type lectin-domain containing receptor kinase IV.2
- At2g42750/F7D19.25
- Molecular chaperone Hsp40/DnaJ family protein
- Fantom protein
Sequence:
MEISSFPFPYLQDDECSHFLGLFQDMDSSPSTFGLEGFNSNDNNTNQKKRPRKDDEGGGGGGGGTEVLGAVNGNNKAAFGDILATLLLLDEEAKQQQEQWDFEFIKEKSLLEANHKKKVKTMDGYYNQMQDHYSAAGETDGSRSKRARKTAVAAVVSAVASGADTTGLAAPVPTADIASGSGSGPSHRRLWVKERTTDWWDRVSRPDFPEDEFRREFRMSKSTFNLICEELDTTVTKKNTMLRDAIPAPKRVGVCVWRLATGAPLRHVSERFGLGISTCHKLVIEVCRAIYDVLMPKYLLWPSDSEINSTKAKFESVHKIPNVVGSIYTTHIPIIAPKVHVAAYFNKRHTERNQKTSYSITVQGVVNADGIFTDVCIGNPGSLTDDQILEKSSLSRQRAARGMLRDSWIVGNSGFPLTDYLLVPYTRQNLTWTQHAFNESIGEIQGIATAAFERLKGRWACLQKRTEVKLQDLPYVLGACCVLHNICEMRKEEMLPELKFEVFDDVAVPENNIRSASAVNTRDHISHNLLHRGLAGTRTL
Protein: Protease Do-like 7 (EC 3.4.21.-) (Q8RY22)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable serine protease.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Protease Do-like 8, chloroplastic
- Protease Do-like 5, chloroplastic
- Protease Do-like 1, chloroplastic
- Protease Do-like 2, chloroplastic
- Putative protease Do-like 6, chloroplastic
- Protease Do-like 10, mitochondrial
- Putative Do-like 15 protein
- Putative protease Do-like 14
- Putative protease Do-like 12, mitochondrial
- Glyoxysomal processing protease, glyoxysomal
Sequence:
MGDPLERLGSQASMATESVMKEDLCLEIDPPLTESVATAEDWRRALGKVVPAVVVLRTTACRAFDTESAGASYATGFIVDKRRGIILTNRHVVKPGPVVAEAMFVNREEIPIYPVYRDPVHDFGFFCYDPSAVQFLTYQEIPLAPEAASVGLEIRVVGNDSGEKVSILAGTLARLDRDAPHYKKDGYNDFNTFYMQAASGTKGGSSGSPVIDWQGRAVALNAGSKSSSASAFFLPLQRVVRALSFLQKSIDSRTDKPKAVHIPRGTLQMTFLHKGFDEIRRLGLRSETEQVVRHASPTGETGMLVVDSVVPSGPADKHLEPGDVLVRVNGTVLTQFLNLENLLDDGVGQILELEIERGGQPLSVSVSVQDLHSITPDHFLEVSGAVIHPLSYQQARNFRFPCGLAYVADPGYMLFRAGVPRHAIIKKVANEDISSLGDLVSVLSKLSRGARVPLEYMSHTDRHRKKSVLVTIDHHEWYAPPQLYTRNDSSGLWDAKPAIEPASVSPSIGNNGFPISQDISLCHHDTEPMHEVNVRGVTDIAAIMETSSGDGSQNDFGSEAKKQRVDEDSSDGIAANGSLYGSEFKSDDAMETDTTVLRDFEGATALSANASLAERAIEPALVMFEVHVPPSCSLDGVHSQHFFGTGIIIYHSSNMGLAVVDKNTVAISASDVMLSFAAFPVEIPGEVVFLHPVHNYALIAYNPSAMDPASASVIRAAELLPEPALQRGDSVYLVGLSRNLQATSRKSIVTNPCAALNIGSADSPRYRATNMEVIELDTDFGSSFSGALTDEQGRIRAIWGSFSTQVKYSSTSSEDHQFVRGIPVYAISQVLEKIITGGNGPALLINGVKRPMPLVRILEVELYPTLLSKARSFGLSDEWIQVLVKKDPVRRQVLRVKGCLAGSKAENLLEQGDMVLAVNKMPVTCFNDIEAACQTLDKGSYSDENLNLTILRQGQELELVVGTDKRDGNGTTRVINWCGCVVQDPHPAVRALGFLPEEGHGVYVTRWCHGSPAHRYGLYALQWIVEVNGKKTPDLNAFADATKELEHGQFVRIRTVHLNGKPRVLTLKQDLHYWPTWELRFDPETALWRRNILKALQ
Protein: Pentacotripeptide-repeat region of PRORP domain-containing protein (I1HB13)
Organism: Brachypodium distachyon (Purple false brome) (Trachynia distachya)
Interaction partners:
Sequence:
MASLLFLPHTTPAPTLRAKLLPGPRTIITCGPRDNRGPLQRGRSLSTEAIHAVQALKRLTAADRSPPAATAAASAALGRLLRADLLAAMAELQRQGHWSLALAALHVARAEPWYRPDPELYATFVSSSPSNDPAAAAAVDALVEAFIEEKERGAAGGSSEGVWVGEDVYKLTRLVRALVAKGRARAAWRVYEAAVRKGGCEVDEYMYRVMAKGMKRLGLDEEAAEVEADLADWEARHLPDEMRPREKSKTAVTGSVV
Protein: A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) (Q02952)
Organism: Homo sapiens (Human)
Function: Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
Subcellular location: Cytoplasm, cell cortex {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000305}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=May be part of the cortical cytoskeleton.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit gamma
- Beta-2 adrenergic receptor
- Calmodulin-like protein 3
- Calmodulin-like protein 4
- Calmodulin-1
- Calmodulin-like protein 6
- Calmodulin-like protein 5
- A-kinase anchor protein 1, mitochondrial
Sequence:
MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNGQLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES
Protein: Guanylate-binding protein 8 (Q2V6D6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MTQPQMAPICLVENHNEHLSVNHEAIEILEKISQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFPLGSTVQSQTKGIWMWCMPHPTKPEHTLVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFIYNSMNTISHDSLEKLHYVTELTELIRAKSSPNPDGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDEYLENALKLIPGLGILVTTYVDAINSGAVPCVDDAVTTLAQRENSVAVQRAADHYSEQMVQRLSLPTDTLQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELIGEAKVLFLLKNEEASDKYCQEELDRLSKDLMDNISTFSVPGGHRLYMDMREKIEHDYWQVPRKGVKAREVFQSFLQSQAIIESSILQADTALTAGQKAIAEERTKKEAAEKEQDLLRQKQKEQQEYMEAQEKRNKENIEQLRRKLEQEREQLIKDHNMMVEKKLKEQKALLEEGFKKKAEEMDGEIQQLKHNIEDMKKKQWFHFRYYYKRSCFIYFFSHFND
Protein: Cytosolic iron-sulfur protein assembly protein 1 (Q05583)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
Subcellular location: Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Interaction partners:
- MIP18 family protein YHR122W
- DNA repair/transcription protein MET18/MMS19
- Cytosolic Fe-S cluster assembly factor NAR1
- Cytosolic Fe-S cluster assembly factor NBP35
- Cytosolic Fe-S cluster assembly factor CFD1
- General transcription and DNA repair factor IIH helicase subunit XPD/RAD3
- Mitochondrial division protein 1
- Pre-mRNA-processing factor 17
- DNA polymerase delta catalytic subunit
- Fe-S cluster assembly protein DRE2
Sequence:
MASINLIKSLKLYKEKIWSFDFSQGILATGSTDRKIKLVSVKYDDFTLIDVLDETAHKKAIRSVAWRPHTSLLAAGSFDSTVSIWAKEESADRTFEMDLLAIIEGHENEVKGVAWSNDGYYLATCSRDKSVWIWETDESGEEYECISVLQEHSQDVKHVIWHPSEALLASSSYDDTVRIWKDYDDDWECVAVLNGHEGTVWSSDFDKTEGVFRLCSGSDDSTVRVWKYMGDDEDDQQEWVCEAILPDVHKRQVYNVAWGFNGLIASVGADGVLAVYEEVDGEWKVFAKRALCHGVYEINVVKWLELNGKTILATGGDDGIVNFWSLEKAA
Protein: Receptor for retinol uptake STRA6 (Retinoic acid-responsive protein) (Retinol-binding protein receptor STRA6) (Stimulated by retinoic acid gene 6 protein) (O70491)
Organism: Mus musculus (Mouse)
Function: Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (By similarity). Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid and 11-cis-retinal. STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency. Does not transport retinoic acid (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:9203140}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q0V8E7}. Note=In the retinal pigment epithelium localizes to the basolateral membrane (PubMed:22467576, PubMed:24852372). Plasma membrane of the basal pole of Sertoli cells, absent in plasma membrane of neighboring spermatogonia (PubMed:9203140). {ECO:0000250|UniProtKB:Q0V8E7, ECO:0000269|PubMed:22467576, ECO:0000269|PubMed:9203140}.
Interaction partners:
- Retinol-binding protein 4
- Retinol-binding protein 1
- Transthyretin
- Lecithin retinol acyltransferase
- Cytochrome P450 26A1
- Retinol dehydrogenase 10
- Retinal dehydrogenase 2
Sequence:
MESQASENGSQTSSGVTDDYSSWYIEEPLGAEEVQPEGVIPLCQLTAPPALLHACLASLSFLVLLLLALLVRRRRLWPRCGHRGLGLPSPVDFLAGDLSWTVPAAVFVVLFSNLCLLLPDENPLPFLNLTAASSPDGEMETSRGPWKLLALLYYPALYYPLAACASAGHQAAFLLGTVLSWAHFGVQVWQKAECPQDPKIYKHYSLLASLPLLLGLGFLSLWYPVQLVQSLRHRTGAGSQGLQTSYSEKYLRTLLCPKKLDSCSHPASKRSLLSRAWAFSHHSIYTPQPGFRLPLKLVISATLTGTATYQVALLLLVSVVPTVQKVRAGINTDVSYLLAGFGIVLSEDRQEVVELVKHHLWTVEACYISALVLSCASTFLLLIRSLRTHRANLQALHRGAALDLDPPLQSIHPSRQAIVSWMSFCAYQTAFSCLGLLVQQVIFFLGTTSLAFLVFVPLLHGRNLLLLRSLESTWPFWLTVALAVILQNIAANWIFLRTHHGYPELTNRRMLCVATFLLFPINMLVGAIMAVWRVLISSLYNTVHLGQMDLSLLPQRAASLDPGYHTYQNFLRIEASQSHPGVIAFCALLLHAPSPQPRPPLAPQDSLRPAEEEEGMQLLQTKDLMAKGAGHKGSQSRARWGLAYTLLHNPSLQAFRKAALTSAKANGTQP
Protein: FMR1-interacting protein NUFIP1 (Nuclear FMRP-interacting protein 1) (Q641W3)
Organism: Rattus norvegicus (Rat)
Function: Binds RNA.
Subcellular location: Nucleus {ECO:0000250}. Note=Distributed in the nucleus in a dot-like pattern. {ECO:0000250}.
Interaction partners:
- Phosphatidylinositol-glycan biosynthesis class W protein
- Box C/D snoRNA protein 1
- PIH1 domain-containing protein 1
- Nucleolar protein 56
- Nucleolar protein 58
- Elongator complex protein 2
- Interactor of little elongation complex ELL subunit 1
- DNA excision repair protein ERCC-6
- FACT complex subunit
- ALF transcription elongation factor 1
Sequence:
MAEPTPAGWPSAPELTPAPGTPSEAAPPQDNWVYWAMLPPPPPPLSSPVAGTEPCQKEQPHVEPQPTSGAFPPFDAQILPAAQPPFDAQAPPDGQSQFNDQQAWNFQASTPWYWGLSPNGFPTYNTSFHSPATHSYFPQSYANYNDFNLPQNRKQKKKKRKEPVFHFFCDTCDRGFKNQEKYDIHMSEHKKCPEVDCSFSAHEKIVQFHWRNMHAPGMKKIKLDTPEDIARWREERRKNYPTLANIERKKLLQLEKEKRGEVLTTTQYGKMKGMSRHSQMAKIRSPGKHYKWKSGGARQRAVLGLGNRARDLKPEIPTKVNVDPLGVLIHSDSESDKDEKSQRAIVPKEVTPALCSLMSSYGNVSGSESEPEEAPIKTEAEVLAENRVLPSSPPKSPRHNVRTTARTVLRAKWKAQRSGLRKITLKQKKSPCHPLFEPRTRHPHLLEMLLAPDIRHERNVILQCVRYIIKKDFFGLTAGSVKTEDV
Protein: CCR4-NOT transcription complex subunit 2 (F8W145)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETD
Protein: ATP-dependent Clp protease ATP-binding subunit ClpX (P50866)
Organism: Bacillus subtilis (strain 168)
Function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Probably the major protease that degrades proteins tagged by trans-translation.
Interaction partners:
- ATP-dependent Clp protease proteolytic subunit
- ATP-dependent protease subunit ClpQ
- ATP-dependent zinc metalloprotease FtsH
- Lon protease 1
- Translocation-enhancing protein TepA
- Cell division protein FtsZ
- Chaperone protein DnaK
- Adapter protein MecA 1
- Trigger factor
- Chaperonin GroEL
Sequence:
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQDKTSA
Protein: Shootin-1 isoform X2 (Shootin3) (A0A2Z6I959)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDTTPLSAGCVSEMEAGGDAEEGEAREGSTECQRLTAERDEAERQLKHIKRVSQMVIEEVNVLQTQLEIEKSCRENAEALATKLNCENRKLKYLSLSSRPCLDELLPSISDCISLEEEVEQQDHSSDSFSQYKQQVKDLQETVSSLLEEKKQLACQLQEQQRQIKELTALREKEQAEMKELYKTIDQQSKTIKRFNRVSMVATTEYENMKEQLDLEQSLRQKAETYAHEMMVKQKEANRQSMILLQQADPSIQLLKALEDVANVTKTLEEERMQHQEKVKALETELEQCALRKQLVQLQRQLEILDEEKKETEGRLQEEEKKNTILEEKVKDLQEARTSSDSASGPSPGTAPPPAPPPQPPPPPPPPPPPPPPPPPSRCNPLSSLIAIMRKSSKGGKGTPKLEQAPVNEAVDDVKVKAVNEMMERIKHGVVLRPVKSQDTKRFGTKLPSPVTAAAAAAVEEKHQESAMEELKGILETVKKSPSRGFQEVAHVKKDSELEVILRRRRKQACDTGAEDNGQLSKVSSSNSLNGRHSSDSGKDTEGPSSSSLSGSERGSRTSSDSGREPAVVQQSSDSGMESKGAAQTDSDCRSLTEKEPIEPITNGCCSGEGQDGDPEKWTGPNGIGHSVAHGDLQTTISSSAQSPNAANSSTDAEC
Protein: Cathepsin E-A (EC 3.4.23.34) (Q805F3)
Organism: Xenopus laevis (African clawed frog)
Function: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation (By similarity).
Subcellular location: Endosome {ECO:0000250}. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. {ECO:0000250}.
Interaction partners:
Sequence:
MRQILVLLLFATLVYGLIRVPLKRQKSIRKTLKEKGKLSHIWTQQGIDMVQYTDSCSNDQAPSEPLINYMDVEYFGEISVGTPPQNFTVIFDTGSSNLWVPSVYCISQACAQHDRFQPQLSSTYESNGNNFSLQYGTGSLSGVIGIDAVTVEGILVQNQQFGESVSEPGSTFVDAEFDGILGLGYPSIAVGDCTPVFDNMIAQNLVELPMFSVYMSRNPNSAVGGELVFGGFDASRFSGQLNWVPVTNQGYWQIQLDNVQINGEVLFCSGGCQAIVDTGTSLITGPSSDIVQLQNIIGASAANGDYEVDCSVLNEMPTVTFTINGIGYQMTPQQYTLQDGGGVCSSGFQGLDIPPPAGPLWILGDVFIGQYYSVFDRGNNRVGLAPVVPYPPLKNGV
Protein: Probable calcium-binding protein CML43 (Calmodulin-like protein 43) (Q9FI19)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Calcium-binding protein that may mediate calcium-dependent signal during plant defense response.
Interaction partners:
- Probable calcium-binding protein CML14
- Calcium-binding protein CML39
- Probable calcium-binding protein CML34
- Calcium-binding protein CML38
- Probable calcium-binding protein CML13
- RING-type E3 ubiquitin transferase
- Probable calcium-binding protein CML40
Sequence:
MEINNEKKKLSRQSSSFRLRSPSLNALRLHRVFDLFDKNNDGFITVEELSQALSRLGLDADFSDLKSTVDSFIKPDKTGLRFDDFAALHKTLDESFFGGEGSCCDGSPESDLEEAFNVFDEDGDGFISAVELQKVLKKLGLPEAGEIEQVEKMIVSVDSNHDGRVDFFEFKNMMQTVVVPS
Protein: 5-methylthioadenosine/S-adenosylhomocysteine deaminase (MTA/SAH deaminase) (EC 3.5.4.28) (EC 3.5.4.31) (Q7NZ90)
Organism: Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / CCUG 213 / NBRC 12614 / NCIMB 9131 / NCTC 9757 / MK)
Interaction partners:
- Probable 6-oxopurine nucleoside phosphorylase
- S-methyl-5'-thioadenosine phosphorylase
- Polyamine aminopropyltransferase
- Acyl-homoserine-lactone synthase
- Ubiquinone biosynthesis O-methyltransferase
Sequence:
MPQSRYEKIISARWIITVETDGEVLENHAIAIRDGKIAAIIPAADAAGLEADERLELPDHVLMPGLINLHGHSAMSLLRGLADDKALMDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMIRGGTTTINDMYFYNAAVARAGLASGMRTFVGCSILEFPTNYASNADDYIAKGMAERSQFLGEDLLTFTLAPHAPYTVSDDTFRKVVTLAEQEDMLIHCHIHETADEVNNSVKEHGQRPLARLQRLGLLSPRLVAAHMVHLNDAEVELAARHGLSTAHNPASNMKLASGISPVSKLMDAGVAVGIGTDGAASNNKLDMLAETRLAALLAKVGTLDPTSVPAAAAIRMATLNGARALGIADKVGSVKVGKQADLIALDLAQLETAPAFDPISHVVYAAGREQVSHVWVKGRALMRERKLTTLDESDLKARAGDWRNRILAK