wanglab/gogpt-training-data huggingface dataset:
Protein: SLAM family member 7 precursor (T cell surface antigen CD2) (A0A0D5CDW0)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MNTKGSVIVLFLCFLTLFTLTDCSTCQKNILEGGSLTFKLTDRPLKDNDRFTIKKDNKVVVLKKNNKQEGPGIVKKDSLELLHVKLSDSGTYGVEVFDVNGTNVKSYTEIVCVYAKVPKPRVTITCQDEKVDFRCDVEVDKDQRSAIFYSWHKNGKELKKNVFNFSINAEEDKSKYTCTAQNPVHNSTSDPVEAACFKRTLFGFDFWFMVGLLAGGGGLVLLLIIVLVTLACRSCRRKDKQQRDEEESRLNYVNASQSSGQQKSKHTARGQPAPPEPYDDVSAQDVPCQAEPKPRSQQRGRPPPPPIDDEEEHPPPLPQPRKKAQVKKREAPL
Protein: CENP-meta, isoform D (EC 5.6.1.3) (M9PD87)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSAKNASSIQVCIKVRPCEPGLTSLWQVKERRSIHLADSHAEPYVFDYVFDEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRVGYIEIYNEKIYDLLNKKNQDLKIHESGNGIVNVNCEECIITSEVDLLRLLCLGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSERADQTGARGARLKEGGHINKSLLFLSNVIKSLSENADNRFTNYRDSKLTRILQASLGGNAFTSIICTIKPSIMEESQSTLSFATRAKKIRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERKNENQQKVEHLERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLELAETGTTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLPDLPLTPKGPLTYDALEKEVTSLRADNEAANSKISELEEKLSTLKQTMRIMEVENQVAVGLEFEFEAHKKSSKLRVDDLLSALLEKESTIESLQKSLDNLTRDVLRNSKEGHMLSIAPEQEDIAGDSICNKCEELEKLIADLESKKNSCECDQLRLEIVSVRDKLESVESAFNLASSEIIQKATDCERLSKELSTSQNAFGQLQERYDALDQQWQAQQAGITTLHEKHEHVQEKYQKLQEEYEQLESRARSASSAEFQRLQNDNTKFQADIASLNERLEEAQNMLTEVQNSESTVEKLRIQNHELTAKIKELETNFEEMQREYDCLSNQLMESVQENDALREEIKQRPTSHVEESMRSSGISSDFDEQKQDINLLHQFVQLSESVQQIELQHHSGISRLFRANQMKLDQSEPGLKLCLESAEYIEEDNRQSDATEPICLKGFLKRHRFQIKRLSQEHVDMGEEKRLLDIISQLEQEIEEKSALMEATEATINEMREQMTNLESALLEKSVIINKVEDYQRQIESLEKQNAEMTMVYEELQDRVTRESSMSESLLRVPPDEDTLPGCPTSPSRREQEVATLKTSITELQSQVSDLKAELENHLRQIQLKDGNIARLQTDFEEMSERCLSMEVRLAELDEDTKQKQELLDRQAQKLSDDLCLIDQLQKKNAQLVEQYHKATESLSLADAKPDQILLSSQYDSQIEKLNQLLNAAKDELHDVRRIKDDEISALRMEFLLQIETNEKENQAKFYAELQETKDRYESNVAELKEKLLQVEETLSSVTVRCQAELEALKSAHKENISQAVEERNNLIVQHQAEMETIRETLKNKLAEASTQQSKMEDAFRAEINEVRATLMEQLNQTKEDRDKGASKLEEVKKTLEQMINGGRVMSDTIAELEKTKAEQDLAVNKLTKDNIELEKQCSKTQEQLQMESLTRDQISFEIEAHIKKLELIVASSKKRIIELEEKCDQQVLELDKCRLEKLSLESEIQKANSEHSCTMEKLQELQAEMKVLSNRNEKEKCDFETKLETFTFKITDLEEVLKEAQHKVILYDDLVSQHERLKICLAEANELSSNLQKKVMSLHTELIDSQKGISSRDVEINELREELKAAMDAKATASAEQMTLVTQLKDVEERMANQAEKFTREAANLKGSINELLLKLNSMQETKDMLESGNEELKEQLRNSQNLRNMLDEESKMCISLKEKLVKLEDAKTSLEQQLRDNKSEIYQRHTELTKEVELGRNRIGELTKKCEELCSDLENSDQIRLDLQETKEQLKKTLENNLGWQQKVDEVTRECEKLRFDMQSKEVQNESKVQELISECEELRSTLKSKEASFQSEKESMDRTISSLLEDKRNLEEKLCSANDIVAKLETEIAALRPRKSLDRNPVPRKSITFESEIRKNRRISVHDERRQSYWNDVREFGIMTDPVDNNCNCAELNSKLQDCQRELFIRESQVTALKMELDHHPLKDENAQLTKRVIEEQDKAKVEQKRLKMKLQDLNARINDLTTASAKEPESNQMAQAAKPATVAAQTQTESDLETILEKTNVKYQEAVRMLRYRYHLIQELKEKLRQNENSDTSNITSLSAGQTSALKAQCESQKKEILAIKYKYEAAKRILAIRNDDLDALREKLAKYETTTSDK
Protein: Agenet domain-containing protein (F4IL23)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEETIRKGSEVEVSSTEEGFADAWFRGILQENPTKSGRKKLRVRYLTLLNDDALSPLIENIEPRFIRPVPPENEYNGIVLEEGTVVDADHKDGWWTGVIIKKLENGKFWVYYDSPPDIIEFERNQLRPHLRWSGWKWLRPDIQELDKSMFSSGTMAEVSTIVDKAEVAWFPAMIIKEIEVDGEKKFIVKDCNKHLSFSGDEARTNSTIDSSRVRPTPPPFPVEKYELMDRVEVFRGSVWRQGLVRGVLDHNCYMVCLVVTKEEPVVKHSDLRPCKVWEDGQTPVIETPSNVMKTKPMRSCSGAKSMTPKRTTKHARRSLNLEKSAETLTKAESRAATGELRSKRANDVINDNTPLVITPQVKPIASVEPVTPSRVRTATPLKQTKADTQGKSSPKKTLEPMRDENGLENSTRQKVLEEKNSEKKGRKRKRQEEHNSDLKETDESCNGQMAEINDTSSICNDVDDQPLAAWINLPTDNFFFFFFFIVLIYPETSIDHSPIVVNNAAIATDVEERQANDTLMILPFAKKSPFWKMYETQEVCKIAPQSPHFSPLFEAKEELREWTAVGMMVSFYGLLEEVKNLQLDVSPSTLGSLSCSFAELEKHGFDVAAPQSRINKMLSLQDERAKKAEERKGLEKKIEAGEIEGHTYEEEMAELELKILELKRQQVVAKEMKEATDKVTSGMKSYAEMINQEIEDLRLEFQSTASAPW
Protein: Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3) (Pregastric esterase) (PGE) (Q29458)
Organism: Bos taurus (Bovine)
Function: Catalyzes the hydrolysis of triacylglycerols to yield free fatty acids, diacylglycerol, monoacylglycerol, and glycerol. Shows a preferential hydrolysis at the sn-3 position of triacylglycerol (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P80035}.
Interaction partners:
- Triacylglycerol lipase
- Triacylglycerol lipase
- Bile salt-activated lipase
- Pancreatic lipase-related protein 2
- Endothelial lipase
- Hepatic triacylglycerol lipase
- Patatin-like phospholipase domain-containing protein 2
- PNPLA domain-containing protein.
- PNPLA domain-containing protein.
- Lipoprotein lipase
Sequence:
MWWLLVTVCFIHMSGNAFCFLGKIAKNPEASMNVSQMISYWGYPSEMHKVITADGYILQVYRIPHGKNNANHLGQRPVVFLQHGLLGSATNWISNLPKNSLGFLLADAGYDVWLGNSRGNTWAQEHLYYSPDSPEFWAFSFDEMAEYDLPSTIDFILRRTGQKKLHYVGHSQGTTIGFIAFSTSPTLAEKIKVFYALAPVATVKYTKSLFNKLALIPHFLFKIIFGDKMFYPHTFLEQFLGVEMCSRETLDVLCKNALFAITGVDNKNFNMSRLDVYIAHNPAGTSVQNTLHWRQAVKSGKFQAFDWGAPYQNLMHYHQPTPPIYNLTAMNVPIAVWSADNDLLADPQDVDFLLSKLSNLIYHKEIPNYNHLDFIWAMDAPQEVYNEIVSLMAEDKK
Protein: AT3g09210/F3L24_8 (Plastid transcriptionally active 13) (Q94AA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Plastid transcriptionally active 3
- RNA-binding
- Translation initiation factor IF3-2, chloroplastic
- Pentatricopeptide repeat-containing protein At2g17033
- RNA-binding protein CP31B
- Pentatricopeptide repeat-containing protein At1g74850, chloroplastic
- ATP-dependent Clp protease ATP-binding subunit
- Translation initiation factor IF-2
- Monothiol glutaredoxin-S14, chloroplastic
- Pentatricopeptide repeat-containing protein At4g31850, chloroplastic
Sequence:
MMKLQGGLLQWSRSSLIPSIYTPINKTQFSIAACVIERNHQLTAKERRQLRNERRESKLGYSWREEVEEKLIKKPKKRYATWTEELNLDTLAESGPQWWAVRVSRLRGHETAQILARALARQFPEMEFTVYAPSVQVKRKLKNGSISVKPKPVFPGCIFIRCILNKEIHDSIRDVDGVGGFIGSKVGNTKRQINKPRPVDDSDLEAIFKQAKEAQEKADSEFEEADRAEEEASILASQELLALSNSDVIETVAESKPKRAPRKATLATETKAKKKKLAAGSTVRVLSGTFAEFVGNLKKLNRKTAKATVGFTLFGKETLVEIDINELVPEIQS
Protein: Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (H0ZG94)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
Interaction partners:
- Uncharacterized protein.
- Aromatic-L-amino-acid decarboxylase
- Aspartate aminotransferase
- Aspartate aminotransferase
- Quinoid dihydropteridine reductase.
- Sulfotransferase
- Tyrosinase
- Thyroid peroxidase
- Amine oxidase.
- Dihydrofolate reductase
Sequence:
MPTPNISTSAAKGFRRAVSELDSKQAEAIMSPRFIGRRQSLIEDARKEREAAAAATDAAESTETIVFEEKDGRAMLNLFFMLKGAKTSPLSRVLKVFETFEAKIQHLETRLSRKPREGIAELEYFVRCEIHSSDLNTFISSIKRVAEDVRTTKEDKFHWFPRKICELDKCHHLVTKFDPDLDLDHPGYSDQVYRQRRKSIAEIAFHYKHGDPIPHVEYTAEETATWKEVYSTLKSLYPTHACKEYLEAFSLLEKFCGYSENNIPQLEEVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADKTFAQFSQDIGLASLGATDEEIEKLATLYWFTVEFGLCRQNGIVKAYGAGLLSSYGELIHSLSDEPEVRDFDPDAAAVQPYQDQNYQPVYFVSESFSDAKNKLRSYAAHIKRPFSVKYEPYTHSIELLDSPQMICHSLESVRDELHSLINALNVIS
Protein: Arabinonate dehydratase (EC 4.2.1.5) (Q97U96)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: Catalyzes the dehydration of D-arabinonate to 2-keto-3-deoxy-D-arabinonate. Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate.
Interaction partners:
- 2-oxoacid oxidoreductase
Sequence:
MIKDIRTYKLCYEGINDERDALAIKGLAEHPMEIVATEIETSDGYVGYGESLAYGCSDAVQVTIEKILKPLLLKEDEELIEYLWDKMYKATLRFGRRGIAIAGISGVDTALWDIMGKKAKKPIYKLLGGSKRKVRAYITGGYYSEKKDLEKLRDEEAYYVKMGFKGIKVKIGAKSMEEDIERLKAIREVVGEDVKIAVDANNVYTFEEALEMGRRLEKLGIWFFEEPIQTDYLDLSARLAEELEVPIAGYETAYTRWEFYEIMRKRAVDIVQTDVMWTGGISEMMKIGNMAKVMGYPLIPHYSAGGISLIGNLHVAAALNSPWIEMHLRKNDLRDKIFKESIEIDNGHLVVPDRPGLGYTIRDGVFEEYKCKS
Protein: Uncharacterized protein (Q9I2V7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Nitrate ABC transporter substrate-binding protein
- Uroporphyrinogen-III C-methyltransferase
- Assimilatory nitrite reductase large subunit
- Assimilatory nitrite reductase small subunit
- Probable serine/threonine-protein kinase
- nitrate reductase
- DNA-binding transcriptional regulator NtrC)
- Nitrate/nitrite transporter
Sequence:
MLRILLIDDTPKKVGRLRAALLESGFEVVDESGLTIDLPARVEALRPDVILIDTESPGRDVMEQVCLVSRDQPRPIVMFTDEHDPGVMRRAIQSGVSAYIVEGIQASRLQPILDVAMARFESDQALRAQLQAREAQLAERKRIELAKGLLMKMKHCGEEEAYTLMRRQAMSRQQRLIQVAEQIIAMHDMLGG
Protein: GTPase activating protein homolog 1 (GTPase activating factor for raC protein BB) (Rho GTPase-activating protein gacBB) (Q54GD0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18334553}. Contractile vacuole {ECO:0000269|PubMed:18334553}. Note=Localized to tubules of the contractile network.
Interaction partners:
- GATA zinc finger domain-containing protein 11
- Rho-related protein racA
- Rho-related protein rac1C
- Rho-related protein racG
- Rho-related protein racF2
- Rho GTPase
- Rho-related protein racH
- Rho-related protein rac1A
- Rho-related protein racE
- Rho-related protein racF1
Sequence:
MNVENQDPNIMVIPNNNLGPIDGNNISPAMNDENSNNGSSFLKNLVNTGTNLLFSSSSSIASPPNLGGLSNDSTNNNSNSNNTIDSSKPLSFENDMSDGYEALVRRSEIAIDQCKELLDFFKKRASEEEKYSKNISNMFSKFKVKDDHDTFQKGVSLLNKINDAESTIHRSFSQNITTNLYHPLNEAIKDMEKSRKRLLEDGKKLKNDLKDSIENVKKSNQKYEKLCREMEQAKLELIEEGNDTKSGKVETLEKKLEKTKLASIKAEDEYKEQINETNEFISGVYQNRLSENLREFQQFELTRLEIMKSNIRNYIGFMKDIPQALQCEIDSTKGFVDIIDPEVDLQNYIMNNSNPKKVLLPFIFEAYNDHKPFVDQHNQNSSSSSSTNALNYASPMSASGSITNTITSQSGSTIISNGASQPIEIPSPQPISEQQQIPPQQQQQQQQAQVPPTSINQSSSPPVNPMGRQQSLKENIFGFFNKATTNLKSSTSSLLTKDGNSTTSSNTSTSNSNQLSKSGIGLPIINTNSIFGVELEVLIENDNSKKKGNGVELEVPLILTQFVQALLKLESFKMDGVFVSLPSHFNIQQEKQKLDQTGTLENITDVYLIASLFKNWIGDLPNPLISYAIYQEIIEAPDNAWKIIESGIPILHRRVLHYIIDFLVDFVNCSKMDTHSISLIFTPVLIRSPFNGDSLLNSKKEVAVIENMIIDSLETKRGNYILKRNLPIIPDDENSDDDDDDSGHIDDENNSSTSGENDINTTNINNNNNVNSNNDTNNNNNNSNTTTTNNNNNNDSNNSNSTNNNNNNNNNNTNNDDNESNNSGYGVSSNGNNINSSVGGSVTHHFLYQTTPTNNVTPVLSDFFDTNSSNGSSKANTNTHNLGVRNSSNISFDTISTNQSDSEPVLVEYDNDDFDILSYK
Protein: CMRF-35-like molecule 4 (CLM-4) (CD300C molecule 2) (Dendritic cell-derived Ig-like receptor 1) (DIgR1) (Immunoglobulin superfamily member 7) (IgSF7) (Leukocyte mono-Ig-like receptor 2) (Myeloid-associated immunoglobulin-like receptor 2) (MAIR-2) (MAIR-II) (Q7TSN2)
Organism: Mus musculus (Mouse)
Function: Acts as an activating receptor in mast cells and macrophages.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11549249, ECO:0000269|PubMed:12893283}; Single-pass type I membrane protein {ECO:0000269|PubMed:11549249, ECO:0000269|PubMed:12893283}.
Interaction partners:
- TYRO protein tyrosine kinase-binding protein
- High affinity immunoglobulin epsilon receptor subunit gamma
- C-type lectin domain family 4, member a3
- Hematopoietic cell signal transducer
- Triggering receptor expressed on myeloid cells 2
Sequence:
MIPRVIRLWLPSALFLSQVPGCVPLHGPSTITGAVGESLSVSCQYEEKFKTKDKFWCRGSLKVLCKDIVKTSSSEEVRNGRVTIRDHPDNLTFTVTYESLTLEDADTYMCAVDISLFDGSLGFDKYFKIELSVVPSEDPVTGSSLESGRDILESPTSSVGHTHPSVTTDDTIPAPCPQPRSLRSSLYFWVLVSLKLFLFLSMLGAVLWVNRPQRCSGGSSSRPCYENQ
Protein: L-arabinitol 4-dehydrogenase (LAD) (EC 1.1.1.12) (A2QAC0)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Function: Catalyzes the NAD-dependent oxidation of L-arabinitol to L-xylulose in the fungal L-arabinose catabolic pathway. L-arabinose catabolism is important for using plant material as a carbon source. Not active with NADP as cosubstrate.
Interaction partners:
Sequence:
MATATVLEKANIGVFTNTKHDLWVADAKPTLEEVKNGQGLQPGEVTIEVRSTGICGSDVHFWHAGCIGPMIVTGDHILGHESAGQVVAVAPDVTSLKPGDRVAVEPNIICNACEPCLTGRYNGCENVQFLSTPPVDGLLRRYVNHPAIWCHKIGDMSYEDGALLEPLSVSLAGIERSGLRLGDPCLVTGAGPIGLITLLSARAAGASPIVITDIDEGRLEFAKSLVPDVRTYKVQIGLSAEQNAEGIINVFNDGQGSGPGALRPRIAMECTGVESSVASAIWSVKFGGKVFVIGVGKNEMTVPFMRLSTWEIDLQYQYRYCNTWPRAIRLVRNGVIDLKKLVTHRFLLEDAIKAFETAANPKTGAIKVQIMSSEDDVKAASAGQKI
Protein: Probable protein phosphatase 2C 38 (AtPP2C38) (EC 3.1.3.16) (Q9LHJ9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May dephosphorylate and repress plasma membrane H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), thus influencing negatively plant growth and fitness (By similarity). Involved in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling. Negatively regulates immune responses by controlling the phosphorylation and activation status of BIK1, a central rate-limiting kinase in PTI signaling. Impairs the phosphorylation of the NADPH oxidase RBOHD by BIK1.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27494702}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- Serine/threonine-protein kinase BIK1
- Probable protein phosphatase 2C 5
- E3 ubiquitin-protein ligase APD4
- E3 ubiquitin-protein ligase APD3
- Probable E3 ubiquitin-protein ligase ATL44
- E3 ubiquitin-protein ligase APD1
- E3 ubiquitin-protein ligase APD2
- LRR receptor-like serine/threonine-protein kinase EFR
- Protein SMALL AUXIN UP-REGULATED RNA 9
- Calcium-dependent protein kinase 28
Sequence:
MVSSATILRMVAPCWRRPSVKGDHSTRDANGRCDGLLWYKDSGNHVAGEFSMSVIQANNLLEDHSKLESGPVSMFDSGPQATFVGVYDGHGGPEAARFVNKHLFDNIRKFTSENHGMSANVITKAFLATEEDFLSLVRRQWQIKPQIASVGACCLVGIICSGLLYIANAGDSRVVLGRLEKAFKIVKAVQLSSEHNASLESVREELRSLHPNDPQIVVLKHKVWRVKGIIQVSRSIGDAYLKKAEFNREPLLAKFRVPEVFHKPILRAEPAITVHKIHPEDQFLIFASDGLWEHLSNQEAVDIVNTCPRNGIARKLIKTALREAAKKREMRYSDLKKIDRGVRRHFHDDITVIVVFLDSHLVSRSTSRRPLLSISGGGDLAGPST
Protein: Mitochondrial fission protein ELM1 (Protein ELONGATED MITOCHONDRIA 1) (Q93YN4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant-specific factor involved in mitochondria fission. Is required for the correct localization of DRP3A from the cytosol to mitochondrial fission sites. Does not seem to be required for peroxisomal division.
Subcellular location: Mitochondrion outer membrane {ECO:0000305|PubMed:18559960}; Peripheral membrane protein {ECO:0000305|PubMed:18559960}.
Interaction partners:
- Dynamin-related protein 3A
- Dynamin-related protein 3B
- Mitochondrial fission 1 protein A
- Peroxisomal and mitochondrial division factor 2
- Peroxisomal and mitochondrial division factor 1
- ELM2 domain-containing protein
- Dynamin
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- Uncharacterized protein T6H20.90
- Phragmoplastin DRP1C
Sequence:
MRPILLPDPPSLSTGVPDIFEQGGSHNVVRRAVVIGNGFPGSENQCIGLVRALGLSDNHLLYRVTRPKGGLNEWLHWLPVGFHKKLDFILRHIYLYSRLMLGSKQSKYISSVPSENGGNVGLASILEADVKGIVNLARQTYEKDGPLIVIACGRDTISIASSIRRLASENVFVVQIQHPRSHLNRFDMVITPRHDYYPLTLEAQEQVPRFMRSWITPREPPQDHVVLTTGALHQIDYASLRKAASAWHDEFAALPKPLVVVNIGWPRSNCRYGADLAKQLTDSLLNVLATCGSVRITLSYKTPAKVSRVIFKELGDNPKVYIWNGQEPNPYMGHLAWGDAFVVTADSVSLISEACSTGKPVYVVGADHCKWKIAEFQKSLRERGVVRSFTGFEDMSESWSYPPLNDTAEAATRIRRELAARGWSLRS
Protein: Leptomycin B resistance protein pmd1 (P36619)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May be a transmembrane transporter of the mating factor, namely P-factor or M-factor. Confers resistance to leptomycin B and to several other antifungal drugs.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mating factor M secretion protein mam1
- Pheromone P-factor receptor
- Uncharacterized protein C2C4.05
- Caffeine resistance protein 5
- Iron-sulfur clusters transporter atm1, mitochondrial
- Regulator of V-ATPase in vacuolar membrane protein 1
Sequence:
MSLHSKKSTSTVKDNEHSLDLSIKSIPSNEKNFSTEKSENEASESHVVDVVKDPFEQYTPEEQEILYKQINDTPAKLSGYPRILSYADKWDIMLQLAGTITGIGAGLGMPLMSLVSGQLAQAFTDLASGKGASSFQHTVDHFCLYFIYIAIGVFGCSYIYTVTFIIAGERIARRIRQDYLHAILSQNIGYFDRLGAGEITTRITTDTNFIQDGLGEKVGLVFFAIATFVSGFVIAFIRHWKFTLILSSMFPAICGGIGLGVPFITKNTKGQIAVVAESSTFVEEVFSNIRNAFAFGTQDILAKLYNKYLITAQRFGINKAIAMGLMVGWMFFVAYGVYGLAFWEGGRLLHAGDLDVSKLIGCFFAVLIASYSLANISPKMQSFVSCASAAKKIFDTIDRVSPINAFTPTGDVVKDIKGEIELKNIRFVYPTRPEVLVLDNFSLVCPSGKITALVGASGSGKSTIIGLVERFYDPIGGQVFLDGKDLRTLNVASLRNQISLVQQEPVLFATTVFENITYGLPDTIKGTLSKEELERRVYDAAKLANAYDFIMTLPEQFSTNVGQRGFLMSGGQKQRIAIARAVISDPKILLLDEATSALDSKSEVLVQKALDNASRSRTTIVIAHRLSTIRNADNIVVVNAGKIVEQGSHNELLDLNGAYARLVEAQKLSGGEKDQEMVEEELEDAPREIPITSFGDDDEDNDMASLEAPMMSHNTDTDTLNNKLNEKDNVVFEDKTLQHVASEIVPNLPPADVGELNEEPKKSKKSKKNNHEINSLTALWFIHSFVRTMIEIICLLIGILASMICGAAYPVQAAVFARFLNIFTDLSSTDFLHKVNVFAVYWLILAIVQFFAYAISNFAMTYAMEAVLQRIRYHLFRTLLRQDVEFFDRSENTVGAITTSLSTKIQSLEGLSGPTLGTFFQILTNIISVTILSLATGWKLGLVTLSTSPVIITAGYYRVRALDQVQEKLSAAYKESAAFACESTSAIRTVASLNREENVFAEYCDSLIKPGRESAIASLKSGLFFSAAQGVTFLINALTFWYGSTLMRKGEYNIVQFYTCFIAIVFGIQQAGQFFGYSADVTKAKAAAGEIKYLSESKPKIDTWSTEGKKVESLQSAAIEFRQVEFSYPTRRHIKVLRGLNLTVKPGQFVAFVGSSGCGKSTTIGLIERFYDCDNGAVLVDGVNVRDYNINDYRKQIALVSQEPTLYQGTVRENIVLGASKDVSEEEMIEACKKANIHEFILGLPNGYNTLCGQKGSSLSGGQKQRIAIARALIRNPKILLLDEATSALDSHSEKVVQEALNAASQGRTTVAIAHRLSSIQDADCIFVFDGGVIAEAGTHAELVKQRGRYYELVVEQGLNKA
Protein: LETM1 domain-containing protein mdm28, mitochondrial (O13920)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:16823372}; Single-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MLRNRLFKTPHQTGFQWRLGAPATGITIRNQPIRSYSGLRGNFLIDKRLSPVKFNKYSPSDIVFYNIGSSRLYSTETPTPSKVKEAPKQVAAEETKPTTVVKKPSIWQRVKGGVLHFWDGTKLLGVEIKISSKLVYKMAVGYELTRRESRQLTRTLKDIGRLVPFSVFVVVPFAELLLPIAVKLFPNLLPSTFEDAKDKEAKKAQLRKTRNEVSNMLRSTLKSGKFTFSNETRESKEFRDFFQKVRTSGQSPSREELIEVCKYFKDDITLDNLSRAQLVAMCRYMNLNAFGTDPLLRYNIRHRMRQIRRDDRAIYIEGINSLSIPELFNACNSRGIRTQGLSPAKLKEELSVWLDMRIKHGIPSVILMLSNAFSYGYNEGTYDSRWDALQDTLASIPDELYHETVVDMPTKQVSNKERLEILREQEELIEEEAEHVAEHPDLAKKQTEENKATSKPAVSAKSPESNIPKNERK
Protein: Probable folate-biopterin transporter 5 (F4KIL8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Could mediate folate transport.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAREEQNIENRGSVHVVERESNLRSVVCGPVRWLKMLASKLHWSYVFAVVSNCGINQGFGYSLGHVATDYYMKDVQKVQPSQYQALSAITRISWIIFKPLFGILTDVLPIFGFHRRPYFILAGVIGVVSLLFISLQSNLHLYLALFWMTISSAAMAIADVTIDACTTYNSNKHPSLASDMQSLCSLSYSIGELLGFFMSGILVHLVGSKGVFGLLTFTFALVSVVGVLFSEPRVHGFSFKQNFTNAMKAMWRTIKCSDVWQPSLYMFITRALGLDIKEGLFYWFTDSKDGPLFAQETVGFILSIGSIGSILGVLLYNLRLKDHPFRKLFLWTQLLFALSGMFDLILVLRLNLKFGLPDYLFIVVDGIVSKMIIRLTWMVIFVLNTKLCPHGIEGTFFALLMSIDNAGLMTSSWLGGKMLHVLKVTRTEFGNLWLAVLVRNVMRLLPICFLFLVPQGDQNTFKLPAEIMGEDSEEEGTRNLELASLVDYVDRS
Protein: Exostosin-like glycosyltransferase 3 (Q9JMA8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004648}.
Interaction partners:
- Exostosin-like 1
- Exostosin-like 2
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
- D-serine modulator-1, isoform CRA_b.
- Heparan sulfate 2-O-sulfotransferase 1
- [heparan sulfate]-glucosamine N-sulfotransferase
- Xylosyltransferase 2
Sequence:
MTGYTMLRNGGVGNGGQTCMLRWSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGNELCEVKHVLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPKVTRGCRLHNCFDYSRCPLTSGFPVFVYDSDQFAFGSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGEIQEPAVLQPADLEKQLHSLPHWRTDGHNHVIINLSRKSDTQNLLYNVSTGRAMVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPSLLISSGCATRLFEALEVGAVPVVLGEQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRSWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI
Protein: FI08023p (Solute carrier family 25 member 46b) (Q9VJA5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004374}.
Interaction partners:
- AT25465p
- GH17939p
- Mitochondrial import inner membrane translocase subunit TIM50-A
- FI08029p
- GH26058p
- Transmembrane GTPase Marf
- AT01605p
- Transmembrane GTPase fzo
Sequence:
MECQELKLVTDKELIDKNLEKEEQTCNLVPAWSPRNPLENSIDCREKSIVENINADQDAIAKIQYLSSEHAKLDKYLDNQEQDESLRKYLVVGVHWVSLLTEHVLSHPFLVLRWQCQVYNASKCYHLHPFTLLPCIVHLHRRQGLTTLWKGMGSCLLVRGMSCAIDDVISKLSSWPKELDSRTTLKRFGQHVLLKSVSIALVLPFHTVSLVKTVQSGIASDKTGLFDVLREGGARIFSWRSPQNTRMLPTWALIGPSISIGITKYLFNLLIHGVSTRMMQRRMLENRCEKNPDNKLENQNAKTYAGLIAMLTTEVVFFPLETILHRLELQGTRTIIDNLDTGYSVVPVLTDYRGLFDCYRVTVISEGAAGLYKGFGAMILQFVAQVAIIKLAKWTADQIAAGILNRPTSRTVQPYNFDSLSCNKSSTTKSPSISSIDVELTSLGKYSLDE
Protein: Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 (EC 3.1.3.95) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Myotubularin-related protein 4) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (Zinc finger FYVE domain-containing protein 11) (Q9NYA4)
Organism: Homo sapiens (Human)
Function: Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:11302699, ECO:0000269|PubMed:16787938, ECO:0000269|PubMed:20736309}; Peripheral membrane protein {ECO:0000269|PubMed:11302699}. Recycling endosome membrane {ECO:0000269|PubMed:20736309}; Peripheral membrane protein {ECO:0000269|PubMed:11302699}. Late endosome membrane {ECO:0000269|PubMed:29962048}; Peripheral membrane protein {ECO:0000269|PubMed:11302699}. Cytoplasmic vesicle, phagosome membrane {ECO:0000269|PubMed:31543504}; Peripheral membrane protein {ECO:0000269|PubMed:11302699}.
Interaction partners:
- Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3
- Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
- Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
- 1-phosphatidylinositol 3-phosphate 5-kinase
- Polyphosphoinositide phosphatase
- Inositol polyphosphate-4-phosphatase type I A
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Phosphatidylinositide phosphatase SAC2
- Inositol polyphosphate 4-phosphatase type II
- Mothers against decapentaplegic homolog 2
Sequence:
MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRLHIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVGLEPWHSNPEGSETSFVDSGVGGPQQTVGEVGLPPPLPSSQKDYLSNKPFKSHKSCSPSYKLLNTAVPREMKSNTSDPEIKVLEETKGPAPDPSAQDELGRTLDGIGEPPEHCPETEAVSALSKVISNKCDGVCNFPESSQNSPTGTPQQAQPDSMLGVPSKCVLDHSLSTVCNPPSAACQTPLDPSTDFLNQDPSGSVASISHQEQLSSVPDLTHGEEDIGKRGNNRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLLSYGCCSKRPNSKQMRATGPCFGGQWAQREGVKSPVCSSHSNGHCTGPGGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS