Protein: Dynein heavy chain, putative (Q386R7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Tubulin beta chain
- Tubulin alpha chain
- Cytoplasmic dynein 2 heavy chain 1
- Dynein heavy chain, cytosolic, putative
- Uncharacterized protein
- Cytoplasmic dynein 2 light intermediate chain 1
- Intraflagellar transport protein IFT88, putative
- Uncharacterized protein
- Intraflagellar transport protein component, putative
- Intraflagellar transport protein 122 homolog
Sequence:
MERSGPIVVESQLLNVVQRHLRVIFGGGNLTRGDGCILFTAQPIPIGGEEEARLTDDLQRLCLTIVRDMTGGRTSLRLPSESEETNFTLVKKQVLPFDKFLKEVGAVDDFPDNIDEVSDQPNIHLVLETLYNDVVSDLPSGAVMVEKFPKVMCPTGKRLDLVMRKASCVQVYSNLSTPLPMERAKSSRPAGDEEENEDADTNGVSGGAAATKKSSGEPQLKVWVNMRVLASAVASYSATPVEHELPIQWRQKSFALAEAREVLGLVYETLRSYWKRNPHSERNKMDAAVLLSIVSGDLQEYVKGQLLLDGRDWRGIWRMNIDQLEKSVELIAEWGSMKEVLLRGEWKDVDVGSEKGGVQSAFEQRLRDVLRIRQLLASAENLSPGKAPESIAPEVVFDGESVTDRRVTSDDRWKTCIGKFEKEFSFLEDHLRGRVKQLFGSNQRGQEDLIRTLKQHRTLLNREGIKNGVEGDMASVAEHLIKQLQKIQVRYENNKRRSTTDLHTVKMAKSAQTECAQIPEIAGILFGKSTSLDQVVKVAEGIMGEMQKEESEALAAWRQNMENHCKKLTSLPDAVVFNGSNKQCITCTVHPSIKQCLQEIYSMRSWCGRRHEELLRISEEGEGVIKACEKLIKATTRSMQVVSNYNTVQRQIIHCTRSMLESASNHALSQLLYKGSDKRLVTIANYNEIDGLNMRFQNAVDALCVENRRIRRFHVDFMNQVAELHNLELAGQTDQWRTAVDGLRRLFEEFLNAHNIDNYDNWRRHLDAQIYKALEHQYQRGLETMHEKMQEFKVELVFKQGQVQFKPSFEAVREAYYQQVRELVGIPLRFRGLQQKKESGGPYELYKLIPLSNKDRIVTVHLKAVELFGKLNRVRKAFRTHVLVGTCGINGGPDIDALVEATCANLKNYSDGFNVVKEQLNKLRDIDDNMKIDGFTISTIPIKASVEEQLHRLEEALLNAMRKTMQQTLSAIDTFVYNASNVITRQPVTMEEVGQANKAYREFVAAMPSYEEKFSEAEELNRVLRQHTGTVIDIGSTKSRWEHLREAIASHHKVIDASMSKMRVSLDSMIQKHMKDGQRFSSKWDKMKAQLLEAFKESKPALIDTTLTQMKDSYNELDELKTQSKELEAKCLHFKLPPPNFHELETTLNDVSQTATMWTLYDNFRESLDTLRKEDWLTFRSHTYVFEDFMKEWKAKLTATANASHMGSDTDVIAQYLHNMLEGWAICVPMFRFVRGEGMMTEHWNEMFRLLEIEKGMTSTDLTFGHILDHHKQLVAAETELKQLHARVQGEVQIREALQDLRAWALEANFTLIAPADSATPAKVKLISEWKETLAQVSDNQSLIGSLKDSPFFSHFADEANGWEVKLANLYEALMLMNTIQRKWTYLEPIFARGALPQEQARFKRVDKEFVSIMQDVEADPRVMTIASQADIVDRLKTILDQIERCQKSLMEFLESKRESFSRFYFISDEDMLEILGHSKSPSVIQAHLKKLFMGINSVIFSEDHKFITHMVSSDREQVELAKPVSIEEDDVEKWLVALDQCMKETLQRLLASCVKVKNIIDPEPINRYPSQVLQVTLQVQFSAAVEEAISKNSLSALGGELKNVLNKLTMFPADTDPVSKLKVKALILDVIHHIEVVEALVAKGVTSTESWWWQKQLRYYMNENELCYVAMMDTKFDYTYEYQGNAAKLVHTPLTDKCYLVLTKGMQLGYGGNPYGPAGTGKTESVKALGSAMGRQVLVFNCDEGIDFKSMGRIFMGIVKCGAWGCFDEFNRLKIDQLSAISQMIQVIQEAIKNREPSCTLLNRLIQVNKNAGIFVTLNPAGKGYGGRSKLPDNLRQLFREVAMTQPNNELITSTMLLSEGFTHAKNLAKKIVEMYRLSGQLMSKQQHYDWGLRSLKAVLHLAGSLVQKWKADNGGNAASEKQEEELVLQSLSINMLSKLSVDDARLFRELAVDVFPQVSIREIAYGELESAIEVAVRELGLQLVKSQVHKVLQLYEALGQRMGVVLVGPSGSGKSTLLRILRKAMQILKIEVPLHVMNPKAIHRQQLLGYMDPDTREWYDGVLSAAARDVVRQPKESRPWILCDGDIDPEWVESLNSVLDDNKLLTLPNGVRIQFGKNVNFIFETHSLAYASPATVSRMGVILFSEDDVSLEPAVRSFLHKQPEERRELLGPLIEKYLIPAVHQTLRLDALVVPTTGMGILNCCLAHILHVANEEDFVFSLLRGLCGMLHPEGAKTITTAVYEMGKVSPVSKKRPLDTYYDHEKKCLKEFASNLTVDSSSGSLLKGELIVPTVDVQRLMATLEPLVSDTNCRPVFLVGPEGSGKSITLQQCFARHSGVRITVLHCSAQTTSLHLIQKLEQMCTISSTSSGHVYRPKEGERLVIILKNVNLPKPDRYGTVELHAFMMQLIMYQGFYNNDLEWIGIEKVQLVASMNPTVSAGRYAVTPRLLAVVGIVFMSYPSKAGLNQIYTEYFKSLISSVPDLGCDLANCPTLSGFVINVFEKICRKREGEEYAHCLFCPRSITNWVTNVLMYEIDSQTTTLPAVLGHEATCIFADCLPRAEDIKKARKTISESLATIGYSSTSSSSADDANSILFVSWLSEADERGQKRLKGVSYEAAAAEVEQGIVKYSREHKTLNIHVIPEVVGWLARVDRVLTRPFGHLILVGRPGVGRRNAVCLAAFLLKMNVVTLNMMQKYALKNFRQDLRQFIQRATTQNERLVLMLEDHNIVDETFLEMINSLVSSGEVPGLFTQEEVETMCASLREDAANDGYMGSIASFYLQRLRRNLRIALVMDNCHPLFLVRLQSNPGLISNCDLLWMGAWSNDATRNICKKRLAAVIDNIGADSANKGFHLHRELFSVHESFGEEATPERFRVLMENYESILQKKGESGEASLKRLDAGLAKLHEAEESVAKIQSDVKRKKKKVEEKQKEADKALTEIQQKMEESKEQRDTAEELQARLSTEQEEIAVKREKVTKELSGITPMLESAREAVSSIRSEQLNEIRSLKAPPEPVKDVLEAVLALLGVNDVSWQSMRKFLGERGVKERILDFDAKNISTPIRENVARLMNQKAGSFKQETIRRASVAAAPMAAWVKAMIDYSTILESIGPLNKQLEDLETNSAKGQEQLKQLKSKLKKIDEAVAKLRKEFSEKCKDAERIKDTLEKAQKELTKAKDLLEKLSGEKTRWSQDAQKIQSSNQLLPKRALVAAAFITYIARETEDVRQRYLKQWSSRLNLPDVVKLTGYMRTDGELLQWKSEGLPSDDLSQENAIAMLDSVQTPLVIDPSNQAIEWVKMNLKTNNIVSEVTSMHDERFSHTLELAVRFGKTLLVMDVDGVEPILYPILRRDIFTAGAKQVVQVGNKQVDWQDKFRIMLFTRRTDIDLPPGAAALVLVVNFSVTKFGLENQLLGVTIQHERPELEQERAALLQKEESLKLELNKLEERLLSDLANSSGDLLENTALIQALNDVKVQASSITEALEKSHKLEAELNEKREVYRPFASNGSTIFFLVKDLENLNRMYHFGLNDFVRLFVECLSGYKGETDIEAKMAGLATNFIQKCFVHVSRGLLERDRLVFGMHLIHGFFPQKFPSSLWNLLVGASAGSANTEGNAASDGSVQLPIWAPPMSRAKFTALLADATASEHVKKWDLNDEKRWGSWILENTPEESLTKNSGLSFMEQLLIVDTFRPDRLADLAHHVIMHSLQLDSLTPLTSLEEMLTGASATTPIILITSGGADPSQEVQEVAYRRMERQRFTQIALGGGQTDDAMLHLRRCAAQGDWLFLKNLHLVLDWAYVLEKELSAMPPPNQDFRLIITTEPHDLFPTVLLRMSLKMTIEAPPGVKQNLMRSYIMWDEGYLRLKTKTLSQMLFGLAWFHALLQERRNYVPQGWIKFYEFSLADMKAASDVFCMLSHNNMDWVTLRGMLQNCIYGGRLENVRDEQVLLKLISKIFNEELLVSCTKALHEKLHVPTTSEHSEVVQFIRDNVSDVDTPALLCLPDNADRAVKEQHTDRLREELRSFVHSAGVSASAKDVWRSLLVPVLEVWKNSGLKGGSTQALSAGQGNYDPMKVFFISEAGLLREIVESVAAKFADLQCVADGLLMPSAALREEAAELISGRAPSNWLDQMDGPKEIGLWLQLLNRRLTVMTTNAQRAFSPSGGVFDLVDFLRPQTFLIALRQYTARTTKAPLVDMSLVAVPKGGKGSASPASGTPCITIKGESIQVQGSLIDAQATVSPVSSSSPSSMPMPTEVQVWWMYGSDKSGGAHIPLYTNATRSTKILDISVPGGEEKDEQLLLGGVAAFLMSV