wanglab/gogpt-training-data huggingface dataset:
Protein: Alpha-(1,3)-fucosyltransferase 7 (bfut7) (EC 2.4.1.-) (Fucosyltransferase 7) (Fucosyltransferase VII) (Fuc-TVII) (FucT-VII) (Galactoside 3-L-fucosyltransferase) (Selectin ligand synthase) (G3MZR2)
Organism: Bos taurus (Bovine)
Function: Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein or a glycolipid-linked sialopolylactosamines chain through an alpha-1,3 glycosidic linkage and participates in the final fucosylation step in the biosynthesis of the sialyl Lewis X (sLe(x)), a carbohydrate involved in cell and matrix adhesion during leukocyte trafficking and fertilization. In vitro, also synthesizes sialyl-dimeric-Lex structures, from VIM-2 structures and both di-fucosylated and trifucosylated structures from mono-fucosylated precursors. However does not catalyze alpha 1-3 fucosylation when an internal alpha 1-3 fucosylation is present in polylactosamine chain and the fucosylation rate of the internal GlcNAc residues is reduced once fucose has been added to the distal GlcNAc. Also catalyzes the transfer of a fucose from GDP-beta-fucose to the 6-sulfated a(2,3)sialylated substrate to produce 6-sulfo sLex mediating significant L-selectin-dependent cell adhesion. Through sialyl-Lewis(x) biosynthesis, can control SELE- and SELP-mediated cell adhesion with leukocytes and allows leukocytes tethering and rolling along the endothelial tissue thereby enabling the leukocytes to accumulate at a site of inflammation. May enhance embryo implantation through sialyl Lewis X (sLeX)-mediated adhesion of embryo cells to endometrium. May affect insulin signaling by up-regulating the phosphorylation and expression of some signaling molecules involved in the insulin-signaling pathway through SLe(x) which is present on the glycans of the INSRR alpha subunit (By similarity).
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Type 2 lactosamine alpha-2,3-sialyltransferase
- Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
- 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3
- Alpha-
- L-Fucosyltransferase
- Alpha-
- Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
- Galactoside alpha-
Sequence:
MQNAGLSPTPSLRALGGLAMAALLSTVWLWWRLGAAPGGAPAPQPTTTILVWHWPFASQPPELPGDTCTRYGVARCRLTVNRSLLAGADAVVFHHRELQTQQARLPLAERPRGQPWVWASMESPSHTRGLGRLRGVFNWVLSYRRDSDIFVPYGRLEPREGPAPPLPAKRGLAAWVVSNFQKRQRRVQLYRQLALHLRVDVFGRAAGQPLCASCLLRAVAGYRFYLSFENSEHRDYITEKFWRNALLAGAVPVVLGPPRAAYEAVAPPDAFVHVDDFGSARELAAFLTSMNESCYRRYFAWRDRFRVRLFSDWRERFCAICARFPQLPRGQVYQDLEGWFQA
Protein: SD04505p (Q960F0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MVAAKYERLNTSGEAAGNGNGNASDAEDEEIELHLAQKTQLGNGHRLRQSNFKYASGKCGSGETPCTNETATLAQENMMMQMAVGTLAIIFLYLALSISLTFYQTDINRQMPFPLAIVTYHLVVKFLLAAAARRIYRMRVGRSRVQLDWRLALRKMAPTGVASAIDIGFSNWGLALVPISLYTMTKSSTIVFILLFAIAFGLEKKSWYLVSIVGLIGTGLLMFTYKSTDFNALGFFFILFASLSSGLRWSFAQFIMQKSKLGLHNPIDMIYYMQPWMIASLVPLVIGIEGAGLIAVIEDLHNHTSNEITWAIARISAGALLAFLMEFSEFLVLCKTSSLTLSIAGIFKDICQLALAVTIRKDHLSVINYIGLIICLAGIVCHLLHKYSNMKEMQRQQELQLDNDQEESSPGEYKFNDGSAIVGVHVKSHSTLTVPLLEQTDSEDESGASNKQNASDVIFDVLKRRDMQR
Protein: Uncharacterized protein (Q381E8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLPGKRSRYIAVASLLPLSGLCYWLLHWWNRRQKGVGNGAATEETDSSSSAGTTTSSASSDCELEENERPKYHEMLMQMKVRGNEFFQEGQYEAALEAYQNCIDACSALGSHDAVAVEVDHVVRVNVILVFLRLKRPEEARMLATFLLQDEACPVRGELKVKALYRRGLASQDIGDLESALCDFRAAVECSPGQSNPAAERAIAELMKRSS
Protein: F-box protein GID2 (Gibberellin-insensitive dwarf protein 2) (Protein GIBBERELLIN INSENSITIVE DWARF2) (Q7XAK4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Essential component of some SCF-type E3 ligase complex that positively regulates the gibberellin signaling pathway. Upon gibberellin treatment, the complex mediates the ubiquitination and subsequent degradation of DELLA protein SLR1, a repressor of the gibberellin pathway, leading to activate the pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:12649483, ECO:0000269|PubMed:14756772}.
Interaction partners:
- DELLA protein SLR1
- Protein SLENDER RICE1-LIKE 2
- Protein SLENDER RICE1-LIKE 1
- SKP1-like protein 1
Sequence:
MKFRSDSSGGDEPRAPAAGDGGGGGDEPAKRQRTDPSSSSSQGEASSSSQPPPQQQQEEQPPEDAGEGEQPRVPDLGEDLVFEVLRRAEARTLAAAACVSRGWRQLAEDERLWEAACVREWANLGFSERQLRAVVLSLGGFRRLHAVYIRPLQWRGAGVPRQQGRRQPPVRLGRDQVQLSLSLFSIGFFQNMPCPKKDKGNDSDKNGGGQCG
Protein: Protein dispatched homolog 3 (Patched domain-containing protein 2) (Q9P2K9)
Organism: Homo sapiens (Human)
Function: Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol (By similarity). Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19179482}; Multi-pass membrane protein {ECO:0000305}. Nucleus membrane {ECO:0000269|PubMed:19179482}; Multi-pass membrane protein {ECO:0000305}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:B9U3F2}; Multi-pass membrane protein {ECO:0000305}. Note=Predominantly localized to cholesterol-enriched domains within the membrane (PubMed:19179482). Localizes to cytoplasmic punctate vesicular structures (By similarity). {ECO:0000250|UniProtKB:B9U3F2, ECO:0000269|PubMed:19179482}.
Interaction partners:
- UbiA prenyltransferase domain-containing protein 1
- F-box only protein 2
Sequence:
MDTEDDPLLQDVWLEEEQEEEEATGETFLGAQKPGPQPGAGGQCCWRHWPLASRPPASGFWSTLGWAFTNPCCAGLVLFLGCSIPMALSAFMFLYYPPLDIDISYNAFEIRNHEASQRFDALTLALKSQFGSWGRNRRDLADFTSETLQRLISEQLQQLHLGNRSRQASRAPRVIPAASLGGPGPYRDTSAAQKPTANRSGRLRRETPPLEDLAANQSEDPRNQRLSKNGRYQPSIPPHAAVAANQSRARRGASRWDYSRAYVSANTQTHAHWRIELIFLARGDAERNIFTSERLVTIHEIERKIMDHPGFREFCWKPHEVLKDLPLGSYSYCSPPSSLMTYFFPTERGGKIYYDGMGQDLADIRGSLELAMTHPEFYWYVDEGLSADNLKSSLLRSEILFGAPLPNYYSVDDRWEEQRAKFQSFVVTYVAMLAKQSTSKVQVLYGGTDLFDYEVRRTFNNDMLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLEDPQLRMIHTVQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVSCCWLAVLVTMPAALGLWSLYLAPLESSCQTSCHQNCSRKTSLHFPGDVFAAPEQVGGSPAQGPIPYLDDDIPLLEVEEEPVSLELGDVSLVSVSPEGLQPASNTGSRGHLIVQLQELLHHWVLWSAVKSRWVIVGLFVSILILSLVFASRLRPASRAPLLFRPDTNIQVLLDLKYNLSAEGISCITCSGLFQEKPHSLQNNIRTSLEKKRRGSGVPWASRPEATLQDFPGTVYISKVKSQGHPAVYRLSLNASLPAPWQAVSPGDGEVPSFQVYRAPFGNFTKKLTACMSTVGLLQAASPSRKWMLTTLACDAKRGWKFDFSFYVATKEQQHTRKLYFAQSHKPPFHGRVCMAPPGCLLSSSPDGPTKGFFFVPSEKVPKARLSATFGFNPCVNTGCGKPAVRPLVDTGAMVFVVFGIIGVNRTRQVDNHVIGDPGSVVYDSSFDLFKEIGHLCHLCKAIAANSELVKPGGAQCLPSGYSISSFLQMLHPECKELPEPNLLPGQLSHGAVGVREGRVQWISMAFESTTYKGKSSFQTYSDYLRWESFLQQQLQALPEGSVLRRGFQTCEHWKQIFMEIVGVQSALCGLVLSLLICVAAVAVFTTHILLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPHQAEDARTQRQWRTLEAVRHVGVAIVSSALTTVIATVPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAPSSFTRTRTSFLKALGAVLLAGALGLGACLVLLQSGYKIPLPAGASL
Protein: Formin-binding protein (Q59UQ6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Inn1p
- Cyk3p
- Ras GTPase-activating-like protein IQG1
- Myosin 1
- chitin synthase
- Formin BNR1
- AP complex subunit sigma
- Formin BNI1
- Apm4p
- Galactose oxidase
Sequence:
MRVSNPQSSKTLFVNNFWGNSPEKSFEIVTTRIKDSLNTLNEIINFYQEKINIEKEYTKKLEKLQSKCILGTNETGTLKQSLDKLSIENQSMINYNHKFIKTIIHTNLEKLQTFQQLYTQRVNKLEHHMGKVLIKRQQALKELEYYKSKYQEECTQLKSLRLSLQTTWGRELEKNQSKFNKINSQINSTRKHYHMALVNYKEINEIYKRDWSISLNDFYKLEVERIQVTKINCFNYCNNIATLCVDQDSAVDLARPMFAQIQPITDLEEFSGNYGTGNKIFNDPEFVDYMTGCEEPRVGYTLSNFPNPDCSNILTRTYSTYTGNGNTSKQVEQKRSDDKLNDNIFTQPHAVQYDPNRVHAPIKEMSKLPIPKLPPTNNRTKTPSPTRKPPSDYHSNYSDDIFSKDERLQSSNGSSDYSSERNWASPRKREKQLQEVQEKISRRATNDFKNIPKIPEPEKVPVIKDFSIDFIAKALEDLNAGGNGDVNQFRRSLRNGRPKSDFIDDSDEVAKRHESINFNRPKSTVPRRSIKLTPVNKKPFVTKAIARYSFKPQTEGELYFKKGWKMYIIHKQEDNWFVCELGDNCLQSSGMIGLVPGNYIVEGDDLF
Protein: Putative heat shock protein HspR (P40183)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Function: Binds to three inverted repeats (IR1-IR3) in the promoter region of the dnaK operon.
Interaction partners:
- Protein GrpE
- Chaperone protein DnaJ 1
- Chaperone protein DnaK
- Heat-inducible transcription repressor HrcA
- Chaperone protein ClpB
- Chaperone protein DnaJ 2
- Co-chaperonin GroES
- Chaperonin GroEL 2
- Putative glycosyltransferase SCO3672
- Chaperonin GroEL 1
Sequence:
MDGRRRNPYELTEDTPVYVISVAAQLSGLHPQTLRQYDRLGLVSPDRTAGRGRRYSARDIELLRQVQQLSQDEGINLAGIKRIIELENQVAELQARAAELAAALDGAATAMRQREAAVHASYRRDLVPYQEVQQTSALVVWRPSRRGQSSD
Protein: Protein translation factor sui1 (P79060)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation.
Interaction partners:
- Eukaryotic translation initiation factor 1A
- Small ribosomal subunit protein eS21
- Eukaryotic translation initiation factor 2 subunit alpha
- Probable eukaryotic translation initiation factor 5
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 3 subunit G
- Probable eukaryotic translation initiation factor 3 subunit J
- Eukaryotic translation initiation factor 3 subunit A
Sequence:
MSAIQNFNTVDPFADTGDDDAQPLNNIHIRIQQRNGRKTLTTVQGLPREFDQKRILRALKKDFACNGTIVKDDDLGEVIQLQGDQRIKVMEFLTQQLGLQKKNIKIHGF
Protein: ATP-binding cassette, sub-family A member 15 (Abca15 protein) (Q8C623)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MASWESRKLLLLLWKNFTLKRRKFGTLVSEIVLVLLLSIVLLTTRHLLSIKKIEALYFPDQPISTVPSFFRASVTSFYPWELAYVPSNIMVVENIVKNVKNDLNLHMKG
Protein: Candida glabrata strain CBS138 chromosome C complete sequence (Q6FX55)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
Sequence:
MNLSSFTPSLRWLIIWTSLIPLLLAKDDYSSSLSNNNLGWTDPTEFPLGCSPNVTTPKNGLSMELYSYDYLKSGSNPCWDAAYLDPNYPRTGYKSHRLLAKVENVAGNINFYYHAPMGCTSLFDTLPQAYNYRTPLTMTNFTMLLYGYFKPKVTGYHTFTISADDLLFVNFGAGNAFDCCKRESSADDFGNYQAYAVWGSQTAKDDLTVHLDAGLYYPIRIFFNNRDNDGALSLTLKTESDPNPVIDFSDYFYSFDDTKDGCPGLVSYDTSCASVDSSTIIGVDYLTETPNKNLVPITKTIYHLGIPCTLSTTGKLCSTGFYDPLADSCVPTTILSTLITSEPSSESSSETLYYSSSRSPSSSVSYSEHTSINSSSPISSITNSTPSLSSQYTSTKFSSITNSTKSPYSPSRSSSSSDISSETNSDSSVYTLPSSSKPITSKTYQKNSTGVMSTSTDVKSTTLCSSVPTSKFGSSRSLESSVIDSTSSFVNNTNHQSFTTESGTTSVNSSNLSTQISRMSSFSTFAKATTKISSSVQTSSHILQSPTTVSYMDHTRNRTEASCSLDITNKLLFQQCAFNSVPEFHSKTQMSRSQIPFATYTTSSDKSVYYSSSGSASGIMVSIESSIGFSISKTNSENTKNPHSIILQIQSEEAFTNYATTTETSSKSKLADNNDSTNVGNIQIETIIQGSGSDLVTMSGATVLFFFIVQLFGMF
Protein: CKII-alpha subunit interactor-1 (RE16596p) (RE17810p) (Q9VUU3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Zinc finger protein ZPR1
Sequence:
MTEAEICKLCKDNRAIEIDLEKPKFKSANKLLQRLFDWYKIDAAILGENYCICEPCFGETLRISESLEKWGTAQDEFHRRPIEIDDSTAFQIKLEVTSNKEEVETEKNDEENSFDQHIAEPVKEDPLEKNEHMEIVVEESLKTASVDFFSVGLSRDGLAVTKFFKDKTQATRMLCTCCGHVLEILTHIRMHSCKPRPNPVYYCRDCGSEFHKLHELHEHMKTMKHNKTMCGAKDLEFLCLRCNQIFPRYFDVIRHENSVHNVSDFICVECNMSFANQGSYRRHTRSHKVKFTQQRFYECPYKDCTSSYRVWARLMSHMSSHGLFSGFKSKVPSTQQERRLLEGKFMTLDPMKRVEPDRRKLPYRKKSFYAKADFPESPTKCTNGGEFISLPKKISLQKGKYINLSDNSRP
Protein: Transcriptional regulator ClgR (ClpR-like regulator) (clp gene regulator) (P9WMH7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Key stress-response regulator that plays an important role in multiple regulatory networks in response to different stress conditions. Involved in preservation of envelope integrity and tolerance to surface stress. Essential for macrophage infection and facilitates intracellular growth of M.tuberculosis. Controls the expression of several protease and chaperone systems, including clpP1, clpP2, clpC1, ptrB, Rv1043c, acr2, clpB, Rv3269 and the clgR-pspA-rv2743c-rv2742c region. Also plays an essential role in RecA/LexA-independent DNA repair mechanism by inducing expression of DNA repair genes in response to DNA damage.
Interaction partners:
- PspA protein
- Putative envelope-preserving system protein Rv2743c
- Putative envelope-preserving system protein Rv2742c
- ATP-dependent Clp protease proteolytic subunit 1
- RNA polymerase sigma factor SigB
- RNA polymerase-binding protein RbpA
- ATP-dependent Clp protease ATP-binding subunit ClpC1
- dUTPase
Sequence:
MAALVREVVGDVLRGARMSQGRTLREVSDSARVSLGYLSEIERGRKEPSSELLSAICTALQLPLSVVLIDAGERMARQERLARATPAGRATGATIDASTKVVIAPVVSLAVA
Protein: POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brain-3B) (Brn-3B) (Brn-3.2) (Q63934)
Organism: Mus musculus (Mouse)
Function: Tissue-specific DNA-binding transcription factor involved in the development and differentiation of target cells. Functions either as activator or repressor by modulating the rate of target gene transcription through RNA polymerase II enzyme in a promoter-dependent manner. Binds to the consensus octamer motif 5'-AT[A/T]A[T/A]T[A/T]A-3' of promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to an octamer site to form a ternary complex with ISL1; cooperates positively with ISL1 and ISL2 to potentiate transcriptional activation of RGC target genes being involved in RGC fate commitment in the developing retina and RGC axon formation and pathfinding. Inhibits DLX1 and DLX2 transcriptional activities preventing DLX1- and DLX2-mediated ability to promote amacrine cell fate specification. In cooperation with TP53 potentiates transcriptional activation of BAX promoter activity increasing neuronal cell apoptosis. Negatively regulates BAX promoter activity in the absence of TP53. Acts as a transcriptional coactivator via its interaction with the transcription factor ESR1 by enhancing its effect on estrogen response element (ERE)-containing promoter. Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to an octamer motif. Involved in TNFSF11-mediated terminal osteoclast differentiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:17668438}. Nucleus speckle {ECO:0000250|UniProtKB:Q12837}. Cytoplasm {ECO:0000269|PubMed:17668438}.
Interaction partners:
- Transcription factor Atoh7
- Insulin gene enhancer protein ISL-1
- Visual system homeobox 2
- Cellular tumor antigen p53
- Melanopsin
- Cone-rod homeobox protein
Sequence:
MMMMSLNSKQAFSMPHAGSLHVEPKYSALHSASPGSSAPAAPSASSPSSSSNAGGGGGGGGGGGGGGRSSSSSSSGSGGSGGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHPSALAGTHHHHHHHHHHHHQPHQALEGELLEHLSPGLALGAMAGPDGTVVSTPAHAPHMATMNPMHQAALSMAHAHGLPSHMGCMSDVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAGI
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (Q93251)
Organism: Caenorhabditis elegans
Interaction partners:
- Acyl-CoA synthetase 7
Sequence:
MLVSILLLCSLLYEFQTLKIINTSYGKLRGMAEWSDDANHKFTFKSVPFAKPPIGNLRFAPPQKLDHWDGILDASVYSAACMSNSTLTTQSYVNEDCLYINIFTSEKCLKSKCSVIVYFHGGAYNTESATMFSDRFILDRYVHEDVIFVIPAVRLGVFGQLYFGPNAYLTENLFMFDAILALDFVHNEISNFGGDPEKVTIMGHSSGGTLVEALGFSSMVDPELKLFQQMIMLSSTGMFGFDDLVIDNSFTIVEKLGCFNGTKEERNTVNVAETLDCMRHIDGYEILRVQQKMELMDQLSFKYLLRGAPFMLLNGNIADLKKNTSPRNAIFGTTEHEFFDVTEKYLYITVTFLDYENPVAVARNYDGRLMKNMETMITGDSAAIFVSTATCAAAMANAGADVFLFETRQSYSVHVSDMQYFIGNHCAHNRTIDIDILDSFYSKLLTNFTKHGKPSPGWDPVDPGRMNYLELKVDSKARSGPVMLEGYHAKDVSFWVGEMTEFDQNVSKMRHSEGLPPERQDTKSQRQYWNFIVYQNFDAKNQQKLVDSTHFIINTTDQAIIFRTDISILYQWWFYLIIAVCAMTIGLVILSFKKSRNGEITPLLS
Protein: Transcription elongation factor SPT5 (A0A8I5ZQE4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR036945}.
Interaction partners:
Sequence:
MSDSEDSNFSEEEDSERSSEAEEAEVEEDRRSAAGSEKEEEPEEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAKSSVGETVYGGSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTPLQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVKEVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMSLKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVVTESTGKEREHNFQPGDNVEVCEGELINLQGKVLSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPRTVGVIVRLERETFQVLNMHGKVVTVRHQAVTQKKDNRFAVALDSDQNNIHVKDIVKVIDGPHSGREGEIRHLYRSFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNLTVGGFTPMSPRISSPMHPSAEGQHGGFGSPGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVDSQRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQIVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIIRMDLEDQQIKILNLRFLGKLLEA
Protein: Krueppel-like factor 6 (B-cell-derived protein 1) (Core promoter element-binding protein) (GC-rich sites-binding factor GBF) (Proto-oncogene BCD1) (Suppressor of tumorigenicity 12 protein) (Transcription factor Zf9) (Q99612)
Organism: Homo sapiens (Human)
Function: Transcriptional activator (By similarity). Binds a GC box motif. Could play a role in B-cell growth and development.
Subcellular location: Nucleus.
Interaction partners:
- Cellular tumor antigen p53
- Transcription factor Sp1
- Transcription factor Jun
- Dual specificity protein phosphatase 1
- G1/S-specific cyclin-D1
- Cyclic AMP-dependent transcription factor ATF-3
Sequence:
MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSPTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSREPSQLWGCVPGELPSPGKVRSGTSGKPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL
Protein: GRCD5 protein (D2T2F9)
Organism: Gerbera hybrida (Daisy)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRGRVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEVALIIFSNRGKLYEFCSSSSMLKTLERYQKCNYGAPDQTNVSAREALELSSQQEYLKLKARYEALQRSQRNLLGEDLGPLNCKELESLERQLDTSLKHIRSARTQLMLDTLTDLQKKEHALNEANRTLKQRLIEGTQINSLHWYPQAPQEVCYDDRQHAPQHQTDEAFFHPLDCGPTLQIGYQTDPINVAGAEAVAGPSMNNYMQGWLPC
Protein: Inner membrane ABC transporter permease protein YejE (P33915)
Organism: Escherichia coli (strain K12)
Function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Uncharacterized protein YejA
- Uncharacterized ABC transporter ATP-binding protein YejF
- Inner membrane ABC transporter permease protein YejB
- Glutathione import ATP-binding protein GsiA
- Nickel import ATP-binding protein NikD
- Probable D,D-dipeptide transport ATP-binding protein DdpD
- Dipeptide transport ATP-binding protein DppD
- Oligopeptide transport ATP-binding protein OppD
- Putrescine export system ATP-binding protein SapD
- Nickel transport system permease protein NikB
Sequence:
MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGATSINFATNKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDAFDPNKAV
Protein: Inactive TPR repeat-containing thioredoxin TTL3 (Tetratricopeptide repeat thioredoxin-like 3) (VH1-interacting TPR-containing protein) (Q9SIN1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in osmotic and salt stress tolerance. May play a role in the control of meristematic cell size during osmotic stress. May function as an adapter protein for BRL2 and may be required for signaling affecting leaf vascular tissue pattern formation.
Interaction partners:
- Serine/threonine-protein kinase BRI1-like 2
- Electron carrier/ protein disulfide oxidoreductase
- Serine/threonine-protein kinase VIK
- Protein EIN6 ENHANCER
Sequence:
MSHSRRLSLEPAIDSITGRFRDLQRNDDDVNKPDFRELDLGSPVSTLMPRGSASSSAAATPTSSSGSSGSASGKPSVSSQMAKRLDDAYKSHSGELSSPGSGMPTTTRILKPGHRRSSSTGTPLIFSGSSFTSATSHTSPQGGGSGATSAVSPNTGVLPAGNICPSGRILKTGMASRTSSRTETLCTGTGNYGHGNVVRSGGGGGTSGKAVRVAENGENPEELKRMGNDMYRRGSFSEALSLYDRAILISPGNAAYRSNRAAALTALRRLGEAVKECLEAVRIDPSYSRAHQRLASLYLRLGEAENARRHICFSGQCPDQADLQRLQTLEKHLRRCWEARKIGDWKTAIKETDAAIANGADSSPQLVACKAEAFLRLKQIEDSDFCVSCIPRLDHHYHSQPQVKLFGMVVEAYVLCIQAQVDMALGRFENAVVKAERAAMLDQTNPEVVSVLNNVKMVVRARTRGNELFSSGRFSEACVAYGDGLKQDDSNSVLYCNRAACWYKLGLWEKSVEDCNHALKSQPSYIKALLRRAASYGKLGRWEDAVKDYEFLRRELPGDSEVAESLERAKTVLMNRSQESKSLGFNNEVEAVSTLDKFKKSVALPGVSVFHFKSSSNRQCEEISPFINTLCLRYPLVHFFMVDVEESMALAKAESIRKVPTFKMYKNGDKVKEMVCPSHQFLEDSIKHFLL
Protein: Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) (Q81CK1)
Organism: Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
Function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
Interaction partners:
- Tryptophan 2,3-dioxygenase
- Kynureninase
- Formamidase
- Formate dehydrogenase alpha chain.
- Formate dehydrogenase alpha chain.
- Oxalate decarboxylase.
- Malate dehydrogenase
- Malate synthase
- Metal-dependent hydrolase.
- Fumarate hydratase
Sequence:
MKTSEWIDISQPLNNNIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFHFDNDGKKVLDLDVQVYVGPARIIDVSNLESIGKKELESFHLEGVERLLLRTSSHGKAEEFPEVIPHLRADIASFLSEKGIRLIGVDVPSVDPLDDKELAAHHQLFKHGIHILENVVLDHVADGDYELIALPLALTDADGSPVRAVIRPI
Protein: Glutathione synthetase GSH2 (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) (Q08220)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Glutamate--cysteine ligase
- Glutathione reductase
- Glutathione hydrolase proenzyme
- Cys-Gly metallodipeptidase DUG1
- Glutathione S-transferase 1
- Glutathione-specific gamma-glutamylcyclotransferase
- Transcriptional regulator URE2
- Peroxiredoxin PRX1, mitochondrial
- Serine hydroxymethyltransferase, cytosolic
- Serine hydroxymethyltransferase, mitochondrial
Sequence:
MAHYPPSKDQLNELIQEVNQWAITNGLSMYPPKFEENPSNASVSPVTIYPTPIPRKCFDEAVQIQPVFNELYARITQDMAQPDSYLHKTTEALALSDSEFTGKLWSLYLATLKSAQYKKQNFRLGIFRSDYLIDKKKGTEQIKQVEFNTVSVSFAGLSEKVDRLHSYLNRANKYDPKGPIYNDQNMVISDSGYLLSKALAKAVESYKSQQSSSTTSDPIVAFIVQRNERNVFDQKVLELNLLEKFGTKSVRLTFDDVNDKLFIDDKTGKLFIRDTEQEIAVVYYRTGYTTTDYTSEKDWEARLFLEKSFAIKAPDLLTQLSGSKKIQQLLTDEGVLGKYISDAEKKSSLLKTFVKIYPLDDTKLGREGKRLALSEPSKYVLKPQREGGGNNVYKENIPNFLKGIEERHWDAYILMELIEPELNENNIILRDNKSYNEPIISELGIYGCVLFNDEQVLSNEFSGSLLRSKFNTSNEGGVAAGFGCLDSIILY
Protein: S-ribosylhomocysteine lyase (EC 4.4.1.21) (AI-2 synthesis protein) (Autoinducer-2 production protein LuxS) (C7M4X6)
Organism: Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / CCUG 9716 / JCM 12966 / NCTC 12371 / SS31 / VPI 2845) (Bacteroides ochraceus)
Interaction partners:
- adenosylhomocysteine nucleosidase
- Cysteate synthase
- 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- cysteine-S-conjugate beta-lyase
- Cystathionine gamma-synthase
- Cysteine synthase
- Aspartate kinase
- Threonine dehydratase
- XRE family transcriptional regulator
Sequence:
MERIASFCIDHLKLERGIYVSRKDYVGNEVLTSFDIRMKLPYREPVLGSPETHTIEHLAATWLRNNPEWKDKIIYWGPMGCMTGNYLILAGDYTSKDIAPLITELFEYIANFEGDIPGASALECGNFYNNNLPFAKYEAKKYLEETLYHLTDKNLNYPK
Protein: Ly49 inhibitory receptor 2 (M0RAM6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MSKQDVPCSTVRFKKSSGLRYQVRPEDTQRPREAGCRVKFPWQLTVIAIGIILSLRLVAVAILVTNIFQYSHETHELQKTRNSHHNSSTMVNDINLKEEMLRKISIENTHCSALLDLINREQDRWYNKTKTVLASPQHTGM