wanglab/gogpt-training-data huggingface dataset:
Protein: Candida glabrata strain CBS138 chromosome J complete sequence (Q6FNM3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome E complete sequence
- Candida glabrata strain CBS138 chromosome G complete sequence
- Candida glabrata strain CBS138 chromosome M complete sequence
Sequence:
MALQVVADYYRCVLENERIYYEYQLNRRETVKNSRSEDEFSGSERTNALKTDEQLQLQRQVNKLTVDLQSMAHENERLREFQKTQKQILESKIQQLKKTVDSFKNERNSSSSSHVRTPPRQTRSGAYTQGKDTDLSRRGGFHLLSPIVGNVNPGKEKAGGLKETLKVGRNTIFDKNSSLLDDDDDDDDDEINGTSVKERSRVTGRKLRSSSSLKDSKNNHIEEEEAMEFTTDNSDEVGLMEGLKLRDGSAKANLQLPSGSLSPDEDTQSSNEETTNTRKKRRRLTRRRIQTMNSDNSSSE
Protein: Alkaline phosphatase (EC 3.1.3.1) (C8V8B5)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Purple acid phosphatase
- Thiamine biosynthetic bifunctional enzyme, putative
- Acid phosphatase
- Acid phosphatase
- Acid phosphatase, putative
- Alkaline phosphatase, putative
- 3-phytase
- GTP cyclohydrolase 1
- Alkaline phosphatase family protein
- Cyclin dependent kinase inhibitor Pho81, putative
Sequence:
MPREEPLLAPRQSSEQSSIRNAEEEDALLTGERTHRGGSRRGWGFWREVGLFSWALIATVAVIILAIVYQRESSWIQSHKKETWGPGGKPTGKRNLIFMVSDGMGPTSLTMTRSFKQLTQGLPADEVLVLDRHILGTSRTRSSSSLVTDSAAGATAFSCGFKSYNGAISVLPDHSPCGTVLEAASLAGYKTGLVVTTRITDATPACFASHANLRQYEDQIAEQEIGEHPLGRVVDLIMGGGRCHFLPNTTDGSCRGDDRDLVAVAKEKGFSYIDDRKGFDSLNGGTEAKLPLLGLFAEKDIPYELDRRTQNDVYPSLEEMARTALKILSHATEDSDQGFFLMIEGSRIDHAGHGNDPAAQVNEVLAYDKAFAAVLEFLNDDSTPGVLVATSDHETGGLAVARQLHDTYPEYLWLPGVLANVSHSSEYAAQKLQDYRRQKTDKPSQEAYTRDLLKKSLGIEDASQQEIDALLDPNNPIIPSYVFADMVSRRAQIGWSTHGHSGVDVNIYASSSRDAWPLQGNHENTEIGAFLADYLDLDVSAVTKRLQNSEFWTAAESISVSESFNWLGNPLGDDVRTDGLDTYHGDFKRKRGFSGDADECGCGGVH
Protein: Etoposide-induced protein 2.4 (p53-induced gene 8 protein) (Q61070)
Organism: Mus musculus (Mouse)
Function: Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).
Subcellular location: Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:15781622}; Multi-pass membrane protein {ECO:0000269|PubMed:15781622}.
Interaction partners:
Sequence:
MADSVKTFLQDLGRGIKDSIWGICTISKLDARIQQKREEQRRRRASSLLAQRRPQSVERKQESEPRIVSRIFQCCAWNGGVFWFSLLLFYRVFIPVLQSVTARIIGDPSLHGDVWSWLEFFLTSIFSALWVLPLFVLSKVVNAIWFQDIADLAFEVSGRKPHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLVGQLVSLLHMSLLYSLYCFEYRWFNKGIEMHQRLSNIERNWPYYFGFGLPLAFLTAMQSSYIISGCLFSILFPLFIISANEAKTPGKAYLFQLRLFSLVVFLSNRLFHKTVYLQSALSSSSSAEKFPSPHPSPAKLKAAAGH
Protein: Serine-threonine kinase receptor-associated protein (Q642N8)
Organism: Xenopus laevis (African clawed frog)
Interaction partners:
Sequence:
MAMRQTPLTCSGHTRPVVDLAFSPITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATINNDATKAATAAADFTAKVWDAVTGDELLSLAHKHIVKSVDFTEDSNNLLTGGQDKVLRIYDLNKPEAEPWEISGHTSAIKKALWYNNNTQILSASDDRTVRLWDRVSMTEVKTLQFGVSVSSMEYIPEGEALLITYGRTIALYDSSSLELIKSFEAPASINSASLHPDKECIVAGGDDFKLYKYDFTTGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTAVGKTYGLWKCVLPEELVSENSDVLYNTSPEIKA
Protein: Guanylyl cyclase-activating protein 1 (Guanylate cyclase activator 1A) (D3ZII9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Retinal guanylyl cyclase 1
- Retinal guanylyl cyclase 2
- Guanylate cyclase 2D
- Guanylyl cyclase-activating protein 2
- Cyclic nucleotide-gated channel alpha-1
- G protein subunit alpha transducin 1
- Cyclic nucleotide-gated channel subunit beta 1.
- Rhodopsin
- Rhodopsin kinase GRK1
Sequence:
MGNVVEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQEEAGAGDLAAEAAG
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (U3KPX3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKRQCLTVLPRLVSNSWAQVILLLQHPKELGLQAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
Protein: Kinetochore protein Nuf2 (Cell division cycle-associated protein 1) (Q76I90)
Organism: Gallus gallus (Chicken)
Function: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (By similarity). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (By similarity).
Subcellular location: Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to kinetochores from late prophase to anaphase and to the centrosome during G1 and S phase.
Interaction partners:
- Uncharacterized protein.
- Uncharacterized protein.
- Kinetochore protein NDC80 homolog
- TTK protein kinase.
- BUB1 N-terminal domain-containing protein.
- BUB1 mitotic checkpoint serine/threonine kinase
- Kinesin motor domain-containing protein
- Centromere protein E
- Dsn1 protein
- Mitotic spindle assembly checkpoint protein MAD2A
Sequence:
MEALTFPRYSPDDIVAYLRSHVLVGAEARNLTKADLFATLKPEVLHMIFIRILQKVYGIRLEHFYMMPVNVDIVYPQIFEGFLPVCNLYIHMERFLPVCRVNDFQMSDVINPKAKRTARFLSGILNFVHFRECRREAYLELQLNYKSAMEKHQQLETANQELEMKLEKLNTVPVEQQAEFKQLSDDIQELEQLLSHDYRRKTAALQEVISQKKSDITERTRKLNELKVTMATLKEEQEQLKSKIVESPEELKNYKELMKETVKKLKKSKQEVIEKYEGYRDLVEVLPSCQLEVQLYQKKMERQAANVERLASVLSEVRNLEDQLESAQIELKKGKTDEMSLKRLVTAKHERLSTAEIRIKKKREDVEQYKHTVFEYFNRVQEKRGVVYDKVTAIQKEIQQMRFKIQQLNESAEEEEMKAKEIYQNLKAGLEKRHDSLIKTAKNYAASREDKIAELQKGLLRVQSPGSSS
Protein: GPN-loop GTPase 2 (EC 3.6.5.-) (ATP-binding domain 1 family member B homolog) (Q08726)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. Required for establishment of sister chromatid cohesion.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14690591}.
Interaction partners:
- GPN-loop GTPase 1
- RNA polymerase II nuclear localization protein IWR1
- DNA-directed RNA polymerase II subunit RPB2
- GPN-loop GTPase 3
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- RNA polymerase II-associated protein RBA50
- DNA-directed RNA polymerase II subunit RPB11
- Bud site selection protein 27
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
Sequence:
MPFAQIVIGPPGSGKSTYCNGCSQFFNAIGRHSQVVNMDPANDALPYPCAVDIRDFITLEEIMQEQQLGPNGGLMYAVESLDNSIDLFILQIKSLVEEEKAYLVFDCPGQVELFTHHSSLFNIFKKMEKELDIRFCVVNLIDCFYMTSPSQYISILLLALRSMLMMDLPHINVFSKIDMLKSYGELPFRLDYYTEVQDLDYLEPYIEKEGSSVLGKKYSKLTETIKELVSDFNLVSFEVLSVDDKESMINLQGVIDKANGYIFGASEVGGDTVWAEASREGALIANYDIQDRWIDNKEKYDKEEEEKRTALLKEQELQNKAVDVNEEDEWENALKEWEEKQGMDFVR
Protein: Paxillin (G1N9N2)
Organism: Meleagris gallopavo (Wild turkey)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MKDALLADLESTTSHISKRPVFLTEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTVIDPLDQWQPSVSRYAHQQPQSQSPIYSSSAKSSSASVPRDGLSSPSPRASEEEHVYSFPNKQKSAEPSPTMTSTSLGSNLSELDRLLLELNAVQHNPPSGFPADEVSRSPSLPNVTGPHYVVPESSSSAGGKAAPPTKEKPKRNGGRGIEDVRPSVESLLDELESSVPSPVPAITVSQGEVSSPQRVTASQQQTRISASSATRELDELMASLSDFKFMAQGKAGGSSSPPSTTPKPGSQLDTMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGVFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFINGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMGKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC
Protein: Catabolite repression control protein (G3XDB0)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- RNA-binding protein Hfq
- Endonuclease III lyase)
- Probable nuclease
- Exodeoxyribonuclease III
- histidine kinase
- Alginate biosynthesis transcriptional regulatory protein AlgB
- Aliphatic amidase
- Bifunctional ligase/repressor BirA
- DNA polymerase I
- Orotate phosphoribosyltransferase
Sequence:
MRIISVNVNGIQAAAERGLLSWLQAQNADVICLQDTRASAFDLDDPSFQLDGYFLYACDAELPEQGGVALYSRLQPKAVISGLGFETADRYGRYLQADFDKVSIATLLLPSGQSGDESLNQKFKFMDDFTHYLSKQRRKRREYIYCGSLYVAHQKMDVKNWRECQQMPGFLAPERAWLDEVFGNLGYADALREVSREGDQFSWWPDSEQAEMLNLGWRFDYQVLTPGLRRFVRNAKLPRQPRFSQHAPLIVDYDWQLSI
Protein: CD44 antigen (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (Phagocytic glycoprotein I) (K7GND9)
Organism: Sus scrofa (Pig)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Cell projection, microvillus {ECO:0000256|ARBA:ARBA00004105}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MDTFWWRAAWGLCLVQLSLAQIDLNITCRYAGVFHVEKNGRYSISKTEAADLCKAFNSTLPTMAQMEAALNIGFETCRYGFIDGHVVIPRIHPNAICAANNTGVYILASNTSQYDTYCFNASAPPEEDCTSVTDLPNTFEGPITITIVNRDGTRYTKKGEYRTNPEDINPNMAPEDDMSSGSSSERSTSGGYSIFHTHLPTTTHPDQEGPWVSSNPEDTPATSTDSNIISAGWEPTEDNEDERDKHPSYSGSGIDDDEDFISSTISTTPGVFNHLQQNEDWTQQSPGHLDPEVSLQTTTRMTDMDRSGTSAHGENWTWDPHSSLSHHENHDEEETQHPTSTTQAIPSSTTEETATQKEQWFENGWSGGYPHTPKEDPHATAGTTAASAHDSHPSERATTQSQVDSSWTHFFDPVSHPMGRGHQTEERMDEDASHSTTLQPSADPHTGLVEDLDRTGLSVTAQQSDTQSSSTSHGGLEEDKDHPVAATPTSSNRNDGRSGRRGGSLPEDSATSVEGYTLHSPDTNEYRTLILVTPTKTGSPGVTEVTIVGDSTSNVDLSSSEDQDPYFDPSGRSFTTHGSESAGHSSGSQEGEANTTSGPIRKSQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINNGNGPVEERKPSGLNGEASKSQEMVHLVNKESTETPDQFMTADETRNLQNVDMKIGV
Protein: Complexin-1 (921-S) (Complexin I) (CPX I) (Synaphin-2) (P63040)
Organism: Mus musculus (Mouse)
Function: Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:15126625, ECO:0000269|PubMed:7635198}. Perikaryon {ECO:0000269|PubMed:7635198}. Presynapse {ECO:0000269|PubMed:7635198}. Note=Enriched at synaptic-releasing sites in mature neurons. {ECO:0000269|PubMed:7635198}.
Interaction partners:
- Synaptosomal-associated protein 25
- Vesicle-associated membrane protein 2
- Syntaxin-1A
- Synaptotagmin-1
- Synapsin-2
- Syntaxin-3
- Syntaxin-4
- Vesicle-associated membrane protein 3
- Synaptosomal-associated protein 23
- Vesicle-associated membrane protein 4
Sequence:
MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREVMRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEPEEEDESILDTVIKYLPGPLQDMFKK
Protein: DELTA-pseudomyrmecitoxin-Pp1a subunit B (DELTA-PSDTX-Pp1a subunit B) (C0HLS3)
Organism: Pseudomyrmex penetrator (Ant)
Function: This heterodimer has insecticidal and cytotoxic properties. Induces immediate paralysis when injected into blowflies (Lucilia cuprina), and then death within 24 hours. Also inhibits the growth of Aedes albopictus mosquito C6/36 cells.
Subcellular location: Secreted {ECO:0000269|PubMed:33344898}.
Interaction partners:
Sequence:
IDPLTILKILKGGLKSICKHRKYLDKACASIGQ
Protein: Uncharacterized protein encoded by LINC01587 (Protein AC1) (Q99440)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDTQKQIHKTHNSKNQFFTIFFFLSVEFGKEGTRKNFYLLLSIGHYGRKSRRADLGTADTADKTEPECFAASWTFDPNPSVTVSGAHSTAVHQ
Protein: Stevor (Q8I4P6)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MNMYYLNMLLFTFLINTLVLPHYENYLNNHYNVSLIQNKTKRATINSRLLAQTKNHNPHYHNDPELKEIIDKLNEEAIKKYQQTHDPYEQLKDVVEKNGTKYTGGNDAEPRSTLEKELLETYEEMFGDECHMLKSGKYQNVDEKSSTCECTDINGGKLSKTKGRDKYLKKLKHRCIGGICSCSVGSFLLTMFGLHAAKAAALAEFTKYGTTYSACKSSITIYSMLSSDSMIAGSTACFTDLTVPAATSAGAIFDPCGITALVLLILAVILIILYIWLYRRRKNSWKHECKKHLCK
Protein: Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL) (EC 2.3.1.225) (P09606)
Organism: Rattus norvegicus (Rat)
Function: Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine. Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation. May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (By similarity). Plays a role in ribosomal 40S subunit biogenesis (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:28323}. Microsome {ECO:0000305|PubMed:28323}. Mitochondrion {ECO:0000305|PubMed:28323}. Cell membrane {ECO:0000250|UniProtKB:P15104}; Lipid-anchor {ECO:0000250|UniProtKB:P15104}. Note=Mainly localizes in the cytosol, with a fraction associated with the cell membrane. {ECO:0000250|UniProtKB:P15104}.
Interaction partners:
- Glutamate dehydrogenase 1, mitochondrial
- Glutaminase liver isoform, mitochondrial
- Glutaminase kidney isoform, mitochondrial
- Amidophosphoribosyltransferase
- Carbamoyl-phosphate synthase, mitochondrial
- Glutamine--fructose-6-phosphate aminotransferase 2
- Glutamine--fructose-6-phosphate aminotransferase 1
- Receptor-interacting serine/threonine-protein kinase 3
- Glutamate decarboxylase 1
- Glutamate decarboxylase 2
Sequence:
MATSASSHLNKGIKQMYMNLPQGEKIQLMYIWVDGTGEGLRCKTRTLDCDPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRRDPNKLVFCEVFKYNRKPAETNLRHSCKRIMDMVSSQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLRCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRIVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCLLNETGDEPFQYKN
Protein: Bacterioferritin (Q5F8H9)
Organism: Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Interaction partners:
- Bacterioferritin
- Ferrochelatase
- Heme transporter CcmA
Sequence:
MQGNQAVVDYMNELLSGELAARDQYFIHSRLYSEWGYTKLFERLNHEMEEETTHAEDFIRRILMLGGTPKMARSELNIGTDVVSCLKADLQTEYEVRDALKKGIKLCEEAQDYVTRDLMVAQLKDTEEDHAHWLEQQLRLIELIGEGNYYQSQL
Protein: Cell adhesion molecule CEACAM16 (Carcinoembryonic antigen-like 2) (Carcinoembryonic antigen-related cell adhesion molecule 16) (CEA cell adhesion molecule 16) (Q2WEN9)
Organism: Homo sapiens (Human)
Function: Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
Subcellular location: Secreted {ECO:0000269|PubMed:25589040}. Note=Localizes to the tip of cochlear outer hair cells and to the tectorial membrane. {ECO:0000250|UniProtKB:E9QA28}.
Interaction partners:
- Alpha-tectorin
- Beta-tectorin
- Otogelin
- Otogelin-like protein
Sequence:
MALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAPLG
Protein: PUM-HD domain-containing protein (Q381T9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPKMRLDFLKNVSQRLATGRSMPLHQVEAALLYGKPAQRAKIVQKILPNVYALSLNKSTHYLLNTLLDKCDGLIRVQVLYQLRRKLVDLSRSNVGNIIVREMLEKLPAKQKKEIAEVFVLNAEEDEFKRLCTHRIGNYVAQKIIEYPSSCEVVEERFLPYLGQLALHEFGQRVVAKYVGVTSDGWKQVCKALFGLDDDVTLKKGKTGDDTLQERISQVIKTTNDNMTLSALLKHPLVPSRVKDALCAHLSEYAGEYLNPQSVCTGAQKGEKVAEDDEFAAPEFGDLPLTKASRGHDQGSPRHLHLYVTVFEYGDFAQRKELWDCIVAAPGLVDHIVSHKFVINVAVAAFKSYPESQDALWNALVGNEGRDVVEVSQDPVGTMLLRAAMEVDNKRFTAAHRRHLAESTLTLSQDPVSSPVIQKLLECSRSDEAVTFLIFESIKGEVQKLVLHSSASYVIQVMLQHGSLKLRGMLVEELIGAFLDMRNVLSYAQGSRVMQKLLAYASDEVVARVAGDFIAASQAEGNKKGDEARGDGRDETGEEQDVGVGGRRLSRKKIREMNRNKHYGVDSHALVSYSLHSHACYVVQALLRECTSRGLDTQRKHLMNELKPFVFELSISPWAGRIVLETMQQCGSAQLKEAMSNVVFLKVETWLTGAGEKEKGQGTGLNPTLRQTLRRTRKEDRNGSESTHESPARKRPFKTAE
Protein: Phosphoenolpyruvate carboxykinase (ATP) 1 (AtPCK1) (PEP carboxykinase 1) (PEPCK 1) (EC 4.1.1.49) (Q9T074)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19807880}.
Interaction partners:
- Phosphoenolpyruvate carboxylase 4
- Pyruvate, phosphate dikinase 1, chloroplastic
- Phosphoenolpyruvate carboxylase 2
- Phosphoenolpyruvate carboxylase 3
- Phosphoenolpyruvate carboxylase 1
- Citrate synthase 3, peroxisomal
- Citrate synthase 4, mitochondrial
- Citrate synthase 5, mitochondrial
- Citrate synthase 2, peroxisomal
- Citrate synthase 1, peroxisomal
Sequence:
MSAGNGNATNGDGGFSFPKGPVMPKITTGAAKRGSGVCHDDSGPTVNATTIDELHSLQKKRSAPTTPINQNAAAAFAAVSEEERQKIQLQSISASLASLTRESGPKVVRGDPAEKKTDGSTTPAYAHGQHHSIFSPATGAVSDSSLKFTHVLYNLSPAELYEQAIKYEKGSFITSNGALATLSGAKTGRAPRDKRVVRDATTEDELWWGKGSPNIEMDEHTFMVNRERAVDYLNSLEKVFVNDQYLNWDPENRIKVRIVSARAYHSLFMHNMCIRPTQEELESFGTPDFTIYNAGQFPCNRYTHYMTSSTSVDLNLARREMVILGTQYAGEMKKGLFSVMHYLMPKRRILSLHSGCNMGKDGDVALFFGLSGTGKTTLSTDHNRYLIGDDEHCWTETGVSNIEGGCYAKCVDLSREKEPDIWNAIKFGTVLENVVFDEHTREVDYSDKSVTENTRAAYPIEFIPNAKIPCVGPHPTNVILLACDAFGVLPPVSKLNLAQTMYHFISGYTALVAGTEDGIKEPTATFSACFGAAFIMLHPTKYAAMLAEKMKSQGATGWLVNTGWSGGSYGVGNRIKLAYTRKIIDAIHSGSLLKANYKKTEIFGFEIPTEIEGIPSEILDPVNSWSDKKAHKDTLVKLGGLFKKNFEVFANHKIGVDGKLTEEILAAGPIF
Protein: Thiamine transporter 1 (ThTr-1) (Solute carrier family 19 member 2) (Q9EQN9)
Organism: Mus musculus (Mouse)
Function: High-affinity transporter for the intake of thiamine. Essential for spermatogenesis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11481326, ECO:0000269|PubMed:11592824}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Thiamine transporter 2
- Thiamine pyrophosphokinase 1
Sequence:
MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVYNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGIVTDTPAANHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFRVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNADIYNGGVEAVSTLLGASAVFAVGYIKLSWSTWGEMTLFLCSLLIAAAVYVMDTVQSIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARGLGLCITTQFLIYASYFAAISVVFLANGIVSIIKKCRKQEDPSSSPQASTS
Protein: Developmentally regulated GTP-binding protein, putative (Q38E85)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RWD domain-containing protein
- ZC3H15/TMA46 family C-terminal domain-containing protein
- TOG domain-containing protein
- ATP-dependent DEAD/H RNA helicase, putative
- 60S ribosomal protein L27a
- Small ribosomal subunit protein uS5
- 60S ribosomal protein L5, putative
- 40S ribosomal protein S15, putative
Sequence:
MGLLERRKAIEEEIARTQKNKKTEYHIGRLKGQLARIKTEMMENATRAAGARGGDGFEVRRSGDVRCALVGFPSVGKSSFLSRVTTTESTAAGYEFTTLTCIPGKLMHRGTEIQILDLPGIIEGAAEGKGRGRQVIATARTADMIILMLDAARAEAQRGKIEAELETVGIRLNQSFPDVTFKKKPSCSMNAIGFTSTVKLTKGMSEGLAKDILKDYGIHNADVIIREDITIDQFIDVIEGNRKYMPCLYIYNKIDTITMEEMDRLSRLPHSVVLSLHWDLNVDEVIDEIWEHLNIIRIYTKKHGSHPDFTKPFVVKRDATVGHICRRIHKDIVSRFKYALVWGTSSKHQPQRVGIQHQLADEDVLQIVVKTSNE
Protein: Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 receptor) (Q63634)
Organism: Rattus norvegicus (Rat)
Function: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Pro-neuropeptide Y
- Peptide YY
- Pancreatic polypeptide prohormone
- Pro-opiomelanocortin
- Relaxin-3
Sequence:
MEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
Protein: Acyl-coenzyme A dehydrogenase (ACDH) (Acyl-CoA dehydrogenase) (EC 1.3.8.7) (EC 1.3.8.8) (Q47146)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the dehydrogenation of acyl-coenzymes A (acyl-CoAs) to 2-enoyl-CoAs, the first step of the beta-oxidation cycle of fatty acid degradation. Is required for E.coli to utilize dodecanoate or oleate as the sole carbon and energy source for growth.
Interaction partners:
- Fatty acid oxidation complex subunit alpha
- Fatty acid oxidation complex subunit alpha
- 3-ketoacyl-CoA thiolase FadA
- 3-ketoacyl-CoA thiolase FadI
- 2,3-dehydroadipyl-CoA hydratase
- Acetyl-CoA acetyltransferase
- Long-chain-fatty-acid--CoA ligase
- Probable acetyl-CoA acetyltransferase
- 2,4-dienoyl-CoA reductase [
- Fatty acid metabolism regulator protein
Sequence:
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLKEHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALVKGLIDKDEAAILVKAEESRLRSINVDDFDPEELATKPVKLPEKVRKVEAA
Protein: Transcriptional regulator ICP22 homolog (IR4 protein) (Immediate-early protein IE68) (In vitro host-range factor) (ORF S1-2) (P68337)
Organism: Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)
Interaction partners:
Sequence:
MPHGQPCGACDGSCRMAQRGTPSTSPLIPSLTPSPPAGDPSPRSSQRIDAVRVPARLPGGSDHPEYGMPLSPRALRPYLARGPGAFCAPPWRPDVNRLAGDVNRLFRGISTSSIHVTEDSRTLRRALLDFYAMGYTHTRPTLECWQSLLQLLPEQSFPLRATLRALNSEDRYEQRFLEPPSDPPNTLFGEECDVSGDESPSEEEEEDEASGESSVSEFSPEEETASSEYDSFSDVGEDDSSCTGKWSSSESESDSESDAPTNNHHPTTRASAAKKRRKRQPPKGERPTKSARR
Protein: RIKEN cDNA 2310002L09 gene (Q9D7L5)
Organism: Mus musculus (Mouse)
Interaction partners:
- Dehydrogenase/reductase SDR family member 7C
Sequence:
MAKCLVKIRTQRSLHLHMMNHCSSNVFVRLLKHGSKVIPRNAGAPLSKVDASEHMVASSPVKGAQSAGSPRKEEDKVKEDPLILSELAYNTSASLLPTQVDDDEVDMLFDCPSRFVLEREDTDTFEDVEADENVFLMAEEEKVKEAHQALSWSYSILTGRIWLNPLVKRCSRLLVVGLGLLLFVFPLVLLLLESGIDISFLFKNMNLSNFTMNTTVL