wanglab/gogpt-training-data huggingface dataset:
Protein: Protein VirD4 (P18594)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MNSSKTTPQRLAVSIVCSLAAGFCAASLYVTFRHGFNGEAMMTFSVFAFWYETPLYMGHATPVFYCGLAIVVSTSIVVLLSQLIISFRNHEHHGTARWAGFGEMRHAGYLQRYNRIKGPIFGKTCGPRWFGSYLTNGEQPHSLVVAPTRAGKGVGVVIPTLLTFKGSVIALDVKGELFELTSRARKAGGDAVFKFSPLDPERRTHCYNPVLDIAALPPERQFTETRRLAANLITAKGKGAEGFIDGARDLFVAGILTCIERGTPTIGAVYDLFAQPGEKYKLFAHLAEESRNKEAQRIFDNMAGNDTKILTSYTSVLGDGGLNLWADPLVKAATSRSDFSVYDLRRKRTCVYLCVSPNDLEVVAPLMRLLFQQVVSILQRSLPGKDERHEVLFLLDEFKHLGKLEAIETAITTIAGYKGRFMFIIQSLSALTGIYDDAGKQNFLSNTGVQVFMATADDETPTYISKAIGDYTFKARSTSYSQARMFDHNIQISDQGAPLLRPEQVRLLDDNNEIVLIKGHPPLKLRKVRYYSDRMLRRLFECQIGALPEPASLMLSEGVHRDGQDLSQQAAVTEAQGLGDIDSIPNNMEAATPQNSEMDDEQDSLPTGIDVPQGLIESDEVKEDAGGVVPDFGVSAEMAPAMIAQQQLLEQIIALQQRYGPASSHSVK
Protein: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I) (3-beta-HSD I) (3-beta-hydroxy-5-ene steroid dehydrogenase) (3-beta-hydroxy-Delta(5)-steroid dehydrogenase) (EC 1.1.1.145) (3-beta-hydroxysteroid 3-dehydrogenase) (EC 1.1.1.270) (Delta-5-3-ketosteroid isomerase) (Dihydrotestosterone oxidoreductase) (EC 1.1.1.210) (Steroid Delta-isomerase) (EC 5.3.3.1) (P24815)
Organism: Mus musculus (Mouse)
Function: A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis. Specifically catalyzes the conversion of pregnenolone to progesterone, 17alpha-hydroxypregnenolone to 17alpha-hydroxyprogesterone, dehydroepiandrosterone (DHEA) to 4-androstenedione, and androstenediol to testosterone. Additionally, catalyzes the interconversion between 3beta-hydroxy and 3-oxo-5alpha-androstane steroids controlling the bioavalability of the active forms. Specifically converts dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR. Also converts androstanedione, a precursor of testosterone and estrone, to epiandrosterone. Expected to use NAD(+) as preferred electron donor for the 3-beta-hydroxy-steroid dehydrogenase activity and NADPH for the 3-ketosteroid reductase activity.
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Interaction partners:
- Cholesterol side-chain cleavage enzyme, mitochondrial
- Steroid 17-alpha-hydroxylase/17,20 lyase
- 17-beta-hydroxysteroid dehydrogenase type 3
- steroid 11beta-monooxygenase
- Aromatase
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1
- Steroid 21-hydroxylase
- Cytochrome P450 11B2, mitochondrial
- Estradiol 17-beta-dehydrogenase 2
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
Sequence:
MAGWSCLVTGAGGFVGQRIIKMLVQEKELQEVRALDKVFRPETKEEFSKLQTKTKVTVLEGDILDAQCLRRACQGISVVIHTAAVIDVTGVIPRQTILDVNLKGTQNLLEACVQASVPAFIFCSSVDVAGPNSYKKIVLNGHEEQNHESTWSDPYPYSKKMAEKAVLAANGSMLKNGGTLNTCALRPMYIYGERSPFIFNAIIRALKNKGILCVTGKFSIANPVYVENVAWAHILAARGLRDPKKSTSIQGQFYYISDDTPHQSYDDLNYTLSKEWGLRPNASWSLPLPLLYWLAFLLETVSFLLRPVYRYRPLFNRHLITLSNSTFTFSYKKAQRDLGYEPLVNWEEAKQKTSEWIGTIVEQHREILDTKCQ
Protein: GPI transamidase component TTA1 (Q7YTW4)
Organism: Trypanosoma brucei brucei
Interaction partners:
Sequence:
MGSSGDLANSAERKLDDEKKRCDWRFTDNTPLIAACLLTGAVVLGVHYISICKDRTDISLPTLMESIESKCRSLGDAFNASAPESVLHPVPTQIGVAIWVAREEWSLPVHDTLDRIEKVVSGAGNRKQQFIQRIVRVSQLGSDGNLEKSSSSSTKWGGSSKVSQDPLANAAIKQQLGLSVAKHAYAVSLKEELLMHTISFFAAPPSAAKSVRCFLFDDKRAYCTVSTEMGMETTKREVEAAVATLLANWLEIENFRDANATQRWAMMRKVRGCHYALRALRQLKMSVDAHPEMPVPEGVRGAADRLEKLVRESDFAKLARAAADLQFHQLLLPQIYIPWDQAVVNHLSILMPVYGVITLAVRLIKENRKRAQVVQNS
Protein: very-long-chain enoyl-CoA reductase (EC 1.3.1.93) (M0R2N5)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MDLNLSLLAREATPGLLPGLNGLPRPTPPKVAKKPKKAVLFFEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL
Protein: Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1) (Q14B46)
Organism: Mus musculus (Mouse)
Function: May play an important role in lymphopoiesis.
Interaction partners:
Sequence:
MEGQLLRGLAAQQDCSIREKIDLEIRMREGIWKLLSLSTKKDQVLHAVKNLMVCSARIQAYTAELQKSKEEIANQTGARLVLDSSSENKEGESCRGKIALSDIRIPLMWKDSDHFSNKECTQRFAIFCLFRMGAQVFDTDMVIVDQTVTDICFENVTIFNEAGPDFQIKIEVYSCSAEESSLTNTPRKLAKKLKTSISKATGRKISAALQEESPEACLLAGSVAGAKYHLLAHTTLTLENAGDCFKTHNLSVHGDEECSFWLPLYGNVCCRLVAQPACMAADAFAGFLNEQQTGKGLVGWRRLYCALRGGKLRCFYGPEEIEAKVEPALVVPIDKETRIQAVEKDSKKMHCFSVLSTAAGRAVSHIFAADSLADFQEWMGAFRQHFFDLSQWKHCCEELMRIEIMSPRKPPLFLAKEATSVYYDMSIDSPVKLESVTDIIQKKIGETNRQFLIGRDDQSAAPPWAAVFDGNHEMVIEKKVLSPIGEPAPDGKRKKRRAPLPPTDQPPFCIKTQGRANQSKDSATQAGVSGASSSPSDPRLSPPTHHLQKPVAAPRKLLPARKNSSADIGHTDTKTSLDAKPVPVPRQKSIRDILDPRSWLQAQV
Protein: Translationally-controlled tumor protein homolog (TCTP) (Q5A860)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Involved in protein synthesis. Involved in microtubule stabilization (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Translation elongation factor 1 subunit beta
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein eS8
- Small ribosomal subunit protein eS1
- Large ribosomal subunit protein eL21
- 60S acidic ribosomal protein P0
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein uL6
Sequence:
MLIFEDVISGDELLSDAYDVKLVDGAVYEADCAMVTVGNGDIDIGANPSAEDGEEALEDGAETVNNVVYSFRLQPTMFDKKSFTTYIKGYMKRIKAYLAENDPDSVEAFEKGATAYVKKVLGSFKDWEFYTGESMDPDAMVVLLNYREDGTTPYVAIWKHGVKENKI
Protein: Probable proteasome subunit beta type-4 (Q09720)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809, ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable proteasome subunit alpha type-5
- Probable proteasome subunit beta type-3
- Probable proteasome subunit beta type-1
- Probable proteasome subunit beta type-2
- Probable proteasome subunit alpha type-3
- Probable proteasome subunit beta type-7
- Probable proteasome subunit beta type-5
- Probable proteasome subunit alpha type-4
- Probable proteasome subunit beta type-6
- Probable proteasome subunit alpha type-6
Sequence:
MESLLAVQGQDFVLTASSSSAVRGITVLKPDDDKSQILNSHNLMLYCGEAGDTTNFAEYIAANISLYTLRHNLNLSPEATASFTRKQLATSLRSRKPYQVNILLAGYETNLGKPELFWLDYLATCVRVPYACQGYSSFYCLSIFDRYYKPDLTIDEAVRIMKLCFDELKKRMPIDFKGFICKVVDKDGIREINI
Protein: Stardust, isoform E (EC 2.7.4.8) (Q7KVT3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRILKQWNRRRSGSSIVVLDGDDLKPCLPDDYISGQHHLNHQQQLQLQQQLQQQHPLQQQHYRTHSGDIREIDQEMLTMLSVNQDNGPHREMAVDCPDTFIARNKTPPRYPPPRPPQKHKKSTNTTTTTTITALTNNDHANKMLIVAYHSSHQHEQLQQQHPSKTSTTTTTIALDVATQNLYNQKQQNKLEQIENYENCLQSERNEQHEQQFEQQKQHQATTAMAATQVAQQQTPSHKLQATLSSDPNGNSNSNNNSHIVGISSSSSSNNSSITDDFLCVVDGLYQGRKDTASPSSSAFDEVMSKHTLDSFGSIAYRHLHQQHQATSNGNSSSNTSNTNSNTNSNTNSNSNTNGNTSNNTAVSTKTATVTKTGVSSSNSNSNSLNSSNSSMHTSSSSSGHSSNIASATSSSSATSSSTVPDDLSLAPPGYEVSQQQQQQHLVATPVTMLLPPMAKHRELPVDVPDSFIEMVKTTPRYPPPAHLSSRGSLLSNGSASTAHTTLSSMGVAPSPVTATAAAAASASAACATTAVAAAAVSGVADGDARRVADELNGNAKPVPPPRDHLRVEKDGRLVNCSPAPQLPDRRAPGNASSGSSGATTHPLQHQQIAQIVEPTLEQLDSIKKYQEQLRRRREEEERIAQQNEFLRNSLRGSRKLKALQDTATPGKAVAQQQQQATLATQVVGVENEAYLPDEDQPQAEQIDGYGELIAALTRLQNQLSKSGLSTLAGRVSAAHSVLASASVAHVLAARTAVLQRRRSRVSGPLHHSSLGLQKDIVELLTQSNTAAAIELGNLLTSHEMEGLLLAHDRIANHTDGTPSPTPTPTPAIGAATGSTLSSPVAGPKRNLGMVVPPPVVPPPLAQRGAMPLPRGESPPPVPMPPLATMPMSMPVNLPMSACFGTLNDQNDNIRIIQIEKSTEPLGATVRNEGEAVVIGRIVRGGAAEKSGLLHEGDEILEVNGQELRGKTVNEVCALLGAMQGTLTFLIVPAGSPPSVGVMGGTTGSQLAGLGGAHRDTAVLHVRAHFDYDPEDDLYIPCRELGISFQKGDVLHVISREDPNWWQAYREGEEDQTLAGLIPSQSFQHQRETMKLAIAEEAGLARSRGKDGSGSKGATLLCARKGRKKKKKASSEAGYPLYATTAPDETDPEEILTYEEVALYYPRATHKRPIVLIGPPNIGRHELRQRLMADSERFSAAVPHTSRARREGEVPGVDYHFITRQAFEADILARRFVEHGEYEKAYYGTSLEAIRTVVASGKICVLNLHPQSLKLLRASDLKPYVVLVAPPSLDKLRQKKLRNGEPFKEEELKDIIATARDMEARWGHLFDMIIINNDTERAYHQLLAEINSLEREPQWVPAQWVHNNRDES
Protein: MIF4G domain-containing protein (Q38F09)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable eukaryotic initiation factor 4A
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
Sequence:
MRTTESSAKPSTNITEERSEVEEAKTNDNIPRCIPYDPEGTVLAMQRLRDVKHRCPAKIANCLQKINKEIAEKLTNAGEALSASPSTSLSSVTVAGPDGRQRTGPPAPLAALPEPWEDRLDAPIAVSNTLGRKRGLFGDVERKELHHHVISILNRVAGDATKYREVKNELLRLPIPEASDEMLKNIVNVFFMKAVREQHFANLYADLVVELCKVPEGQRIVGNKSQSLEFRMRQQLLSRCQEEFQRLEEKNIETANQGGEDRNTQSADESFKERRDRACGIVAFVGQLFLRHIVTEKVIMQILTTTTAGHYGREGLVMPPPYTPSEGQMDELVKLLGIVDSAFFATPLGSSMLVVFTDIMVHWSQHHPVLRIRLLLLSVVERLQKKIGEQNAAAQQQRQQQQQQPPGQTRQSAFEGKRPPNSVGDSQRPVSPSSGGNSPLSVSGVPAAVSVAGVEVAARPIQPPPAARNSLIPAPRSAASRQSSIVVTTPLTSTVSTSFAVKQVATTETVATYMHNVTRCDCTVDMVVDEIANAFENVISVVVVWTERCLTVVKTAKQRVLFGPFLCSVERQCGGTLKEKLRQVAMDAFRNAVRQKLYEDLAIFKYWTEMICSDTAREVLDETLLNEGLDCVMSFDRSAVRIYLRDVAMQLQQRSSGPQREPSLEKNDFIRYRPLQVIHANTAESGVEPILALIDYPDVRKQSIEIDLYCTIVTDNPPKNVLFDSLASSPCLESPLAAAEVFSALLHAWLKSGFANSIQDHVDICLLAVNNRDRATREILLLMELYSVLKNVVPPSTRSIEMGEIALKVLKKGLVTEETRVRAYNYLEPLERNPHHFIGIPPGSIARSEFESSKPVISTLKERKSHSGNGSSGAVRRV
Protein: Nuclear-like sequence (Q8HCP3)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MTRILQLQRSICITPEQWTGEGVSFIYGVWKRGRSRIDCYLKKWNGSDYPLASALTLLTTPTLCLLRFLIHVLMSISICMILILQSIYPLVLPIELLSMFFPFREMVAVPNAELAAVPNDQCLWGFPSLQLSPVSPMCWALNTFQDPVLVGRRFFTFVKVVLRWNRTTLLGFRVQRAKLKRISSPLL
Protein: ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) (Petite colonies protein 9) (P18239)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:795470}; Multi-pass membrane protein {ECO:0000269|PubMed:24474793}.
Interaction partners:
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome c oxidase subunit 4, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Non-selective voltage-gated ion channel 1
- Mitochondrial phosphate carrier protein
- ATP synthase subunit beta, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- ADP,ATP carrier protein 3
- Cytochrome c1, heme protein, mitochondrial
- ATP synthase subunit alpha
Sequence:
MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK
Protein: Uncharacterized protein (G1NEJ8)
Organism: Meleagris gallopavo (Wild turkey)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGSLKTQDEAEAASSSSPTEEQAPKMVMTHVNGFECQPIFLNVLEAIEPAVVCAGHDNSQPDSFSNLLSSLNELGERQLVYVVKWAKALPGFRNLHVDDQMSIIQYSWMGLMIFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRQLSQEFGWLQITPQEFLCMKALLFFSIIPVDGLKNQKLFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKVLDSVHPIAKDLHQFTFDLLIKAHMVSVDYPEMMAEIISVQVPKILSGKVKPIYFHAE
Protein: IFNb1 (B7SVJ8)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MAVLKWLSICLTLFCQGTVASKPCRWTQFRLGKLNDVSIGLLSDMGGLFPLMCAEENVEQMFPEDLYKNTEGEDVSVVALEAMRYVEQLYNNSLTSATWSKTKLNMFQNVIYRQVQNLELCVVGGVWESSGDGWSVTLKTYFNKLNTVLKEKEYSACAWEIVRKEIRENLVQFKKFIDSRVKL
Protein: Villin-2 (Q10L71)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Ca(2+)-regulated actin-binding protein (By similarity). Binds actin microfilaments (MFs). Involved in actin filament bundling, severing and capping. Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. May regulate cell expansion in developing organs. Required for the regulation of plant architecture via the modulation of polar auxin transport and root gravitropism.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O81644}.
Interaction partners:
- Os03g0225600 protein
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 3
- Os11g0157701 protein
- Expressed protein
- Conserved oligomeric Golgi complex subunit 8
Sequence:
MSSAKPVLDPAFQGVGQKPGTEIWRIQDFKPVPLPKADYGKFYNGDSYIVLQTTCSKGGGAYLFDIHFWIGKDSSQDEAGTAAIKTVELDTMLGGRAVQHRELQGYESDKFLSYFKPCIIPLEGGFASGFKTPEEDKFETRLYICKGKRAIRVKEVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKALEAIQHLKETYHNGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKAICDDDVVLETTAPKLYSINNGQLKLEDTVLTKSILENNKCFLVDCGSDLFIWVGRLTQVEERKAASAAVEEFIATQNRPKTTRVTRVIQGYENHTFKSKFESWPVNSAGSAGAEEGRGKVAALLKQQGVDIKGASKSSAPVDEEVPPLLEGDGKLEVYCVNGSAKTALPKEELGKFYSGDCYIVLYTYHSGDKREEFYLTYWIGKDSIPEDQEMAFQTANSIWNSLKGRPILGRIYQGKEPPQFIALFQPMVILKGGISSGYQKFVEEKGLKDETYSGDGIALFRISGTSIHNNKVLQVDAVSSNLSPTDCFVLQSGNSMFTWIGNASSYEQQQWAAKVAEFLKPGVAVKHCKEGTESSAFWFALGGKQNYTSRNATHDVVREPHLYTFSLRNGKLEVTEIFNFSQDDLLTEDMMVLDTHGEVFVWMGQCVDAKEKQKAFEIGQKYAEHAAAFESLSPDVPLYKVVEGNEPCFFRTYFSWDNTRSVIHGNSFQKKLSLLFGMRSESGSKSSGDGGPTQRASALAALSSAFNPSSQKNKGNDRPKSSDGGPTQRASAMAALTSAFNPSAKPKSPPQRAGQGSQRAAAVAALSNVLTAEGSSQSPRIGDADTAELTPSAASPLSEGASEFSADKDAPGDGALSEGGRTEPDVSVEQTANENGGETTFSYDRLISKSTNPVRGIDYKRRETYLSDSEFQTVFGITKEEFYQQPGWKQELQKRKHDLF
Protein: Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1) (P63099)
Organism: Bos taurus (Bovine)
Function: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q63810}. Cell membrane {ECO:0000305|PubMed:6321184}; Lipid-anchor {ECO:0000305|PubMed:6321184}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q63810}. Note=Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. {ECO:0000250|UniProtKB:Q63810}.
Interaction partners:
- Protein phosphatase 3 catalytic subunit alpha
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Nuclear factor of activated T-cells, cytoplasmic 1
- Calmodulin-like protein 4
- CALML5 protein
- EF-hand calcium-binding domain-containing protein 11
- Calmodulin
- Nuclear factor of activated T-cells, cytoplasmic 1
- Nuclear factor of activated T-cells, cytoplasmic 1
Sequence:
MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
Protein: Probable transcriptional regulator (Q9HVJ0)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Nucleotide-diphospho-sugar transferase
- Peptidase S8/S53 domain-containing protein
- Transcriptional regulatory protein AlgP
Sequence:
MVNHPRATMGELAELAGVSRATLNRHCGTREGLKRRLESHARSTLERLTHSAALQRLEPREALRELIREHLAQRDLLALLMFEQNPGRQAGHGDASWQSYVEALDAFFLRGQQKRVFRIDISAATFSELFIVLIYGMVDAERRGRAASAGLSATLEELFLRGASNPAQPASP
Protein: Trihelix transcription factor GT-4 (Trihelix DNA-binding protein GT-4) (Q9LU92)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that binds specific DNA sequence.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein METHYLENE BLUE SENSITIVITY 1
- Probable xyloglucan 6-xylosyltransferase 3
- At5g63780
Sequence:
MFVSDNNNPSRDINMMIGDVTSNGDLQPHQIILGESSGGEDHEIIKAPKKRAETWAQDETRTLISLRREMDNLFNTSKSNKHLWEQISKKMREKGFDRSPSMCTDKWRNILKEFKKAKQHEDKATSGGSTKMSYYNEIEDIFRERKKKVAFYKSPATTTPSSAKVDSFMQFTDKGFEDTGISFTSVEANGRPTLNLETELDHDGLPLPIAADPITANGVPPWNWRDTPGNGVDGQPFAGRIITVKFGDYTRRVGIDGTAEAIKEAIRSAFRLRTRRAFWLEDEEQVIRSLDRDMPLGNYILRIDEGIAVRVCHYDESDPLPVHQEEKIFYTEEDYRDFLARRGWTCLREFDAFQNIDNMDELQSGRLYRGMR
Protein: Calpain-3 (EC 3.4.22.54) (E9QE31)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU367132}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 25 homolog
- rRNA 2'-O-methyltransferase fibrillarin
Sequence:
MAEEQKFSETSVQLTEAAPQTVGSGFTAPGNIYSAILSRNEAVKDARRLKDFQELRDKYVRKKVLFEDPLFPAQDSSLFYSEKFPLKLEWKRPMEICKNPQFILGGANRTDICQGDLGDCWLLAAIACLTLNDVILKRVVPHDQSFTENYAGIFHFQFWRYGEWVDVVIDDRLPTYKNKLVFTRSGQNNEFWSALMEKAYAKLHGSYEALKGGNSLEAMEDFTGGVTEFYEITEAPKELYNIMRKALKRGSLMGCAIDTLVPTAQRTKTASGLVRGHAYSVTGVEQGKRKDGKDLMIRLVRVRDPWGVAPPPACKSNDWVELAKTEQDKQRLQPGEQGEFWMCFEEFQKNFTKLEICNLTPDTLEDDQMFKWNVTVHEGRWVKGCSAGGCRNFPDTYWTNPQFRLVLLEADAKEKTCTVVVALMQKGRRVERCSGATLHNIGFAIYEVPKEMKGNQQQQLSKDFFLYNASTARSKSYVNIREVTERFCLKPGEYVIIPSTFDPHKESEFLLRVFSENRSTSKVIDAEIEAEPMQVDNVKKKIKPFEEEETEEEKQFRAIFQQIAGDDMEINANELRTVLNRVVAKHKELKTEGFSLESCRSMIALLDTDGTGHLNLQEFKHLWNKIKQWKLVFTRFDTDKSSTISSFEMRNALTEAGFQLNNQLYDIICMRYANEHMELDFDSYISCLVRLEGMFRAFRAFDKDGDGLIKLNVFEWLQLTMYA
Protein: Glucosamine 6-phosphate N-acetyltransferase (EC 2.3.1.4) (Q4WCU5)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- Phosphoacetylglucosamine mutase
- glutamine--fructose-6-phosphate transaminase
- Glucosamine-6-phosphate isomerase
- Glucosamine-6-phosphate isomerase
- N-acetylglucosamine-6-phosphate deacetylase
- N-acetylglucosamine-6-phosphate deacetylase
- Phosphotransferase
- Phosphotransferase
- Phosphotransferase
- Hexokinase-1
Sequence:
MTNATIAPTTTAAPVTKSVDAPTADENTPLFSPSLISPDVLAVLPADYTIRPLCRSDYKRGYLDVLRVLTTVGDINEEQWNSRYEWIRARSDEYYLLVVCDGEGRIVGTGSLVVERKFIHSLGMVGHIEDIAVEKGQQGKKLGLRIIQALDYVAEKVGCYKTILDCSEANEGFYIKCGFKRAGLEMAHYY
Protein: Leucine-rich repeat-containing protein 39 (Myosin-interacting M-band-associated stress-responsive protein) (Myomasp) (F1R6I3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress (By similarity). May regulate expression of other M-band proteins via an SRF-dependent pathway (By similarity). Important for normal contractile function in heart.
Subcellular location: Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:D3ZXS4}.
Interaction partners:
- RNA 3'-terminal phosphate cyclase
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
- tRNA methyltransferase 13 homolog.
- Protein phosphatase 1 regulatory subunit 42
- Troponin I type 2b
- Tripartite motif-containing 101.
- diphthine methyl ester synthase
Sequence:
MTGVTVCCGTVNSIKALWETRIKKTKDDLKKEKEQKDRRAVGRLTGAWEDRIILAKLKEKIVTEEGRVILRIEKEEWKTLPPALVQLSQIQEWQLHRIGLQRIPRFISSFQSLIVLDLSRNSVTEIPKEIGKLTRLRELLLSYNRVSYVPEELGCCENLEKLELAMNRDLDELPTQLSNLKKLSHLDLSMNQFTTIPDCVVNLPSLEWLDMGSNILETLPDNIHRMEKLHTLWLPRNELEYLPDNISRMKSLDTLVLSKNKLRDIPPLMEGMSNLRFVNFRDNPLTYDVTLPDLNEDVEEEENDREMFGREFMNFYIQEARKRGSQNFTSVLNVMLEGVSETA
Protein: Cullin, putative (Q57UJ3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- TATA-binding protein interacting
- Ubiquitin, putative
- Ubiquitin-conjugating enzyme E2, putative
- Polyubiquitin, putative
- Ubiquitin-conjugating enzyme E2, putative
- SKP1 component dimerisation domain-containing protein
- S-phase kinase-associated protein, putative
- RING-type domain-containing protein
- RING-type domain-containing protein
- DNA damage-binding protein 1
Sequence:
MPLSGGSNQCSNYTDRNNGSDGVSGEGVGIDGGSDVGIEVDVSAWLVNMPQLGDLWPRVEEYLTQSAAKIRNSGAYTKDPLKGIRHRMSWYAVIYYACAGHPQRFCEIYQYLALFLLNDLETNALPPVLSAVATYADTNPEFDVVARREGFEPPLRPNRSLLQEFVHQFRLFMLFRRVVLSCFGYLDQWYTEKFHLDPVSDLCVKMFYVVVYERVRDELASEIVHSANQARGLSDGPSDDDPSNACLDVQVALAVVSEIVSTVRASSTNTEAGVVHCGPLGKEGSNPSIDGGRSDDVEVEAGTSAPCQTGTSPWELVPDRIPLLREKLESGSLMEFLKSLSSSTGGNQCGGAKVDGPSAARPSGAACGALLGGAHPARSFIVSLVQPLHTLLLDQFGTRYVRAAEAYYRKERSVHLATREGRSGYVTWVRSCYRLEQLLVKDMRAPFFHDLLRARLHRVLLLEVHSEIILDDEFGFRALLDAWSAQTSPHFGALRKDFLKPVVVSSPSSSLEETVHEIMDRCDCASSLQHIGKAAGSMQPMREGLASALGLLVTTFADTQSEICIALLRHELANKVVMDSVPLLATYFVMEEKHHLGHIHPKGRQTNDVEPAFLRDMAKLVVGGLVDMVAQYGSLVQVQFHSLSSMLVAVRDALREVLNPHRWERHTVDTRSGVNVNSGKFSDMLLLDAERQQPPQIHGYEPTRGARAALRKLAAMRDGRSIPMSRLVAVYCDVLVSQSGTRGVAVTADKETEIGGKCVSLPEGSDSTSDIDSVTALAALLDDKDVFLEEYKQLLARRLIILSSSLSLSPSALPTELCTKPNAEYEHAMIRELRRTFGRTSTLTLKMMLHDYTLSCAMGSAFRQTPSAQQLKSGINVQVITGARWPTYSTVPLLPCTSLAAAISTFSTYYAAAHPLRTLSWIHSQGTANLEALFPNGSKEIVADTIQSNILILLSDAYNTVRRNRDSESRRGVGEGKSTKRYLTGQEIASAMGMSFENLYAYLNQLVHHTSYKLITRVPSPNPDPAVDPNEASVRPEYGYTINVDFKHSSNSFRLPVPHPRWNQKASGGHRVVGADAMAASQTFALVTESTRRLQVDAAIVRTMKRHRSLPYHELMSTTVQELSRFFVPSTQFVKVQVEGLIAREFLKRNEANSQLLEYVV
Protein: DNA/RNA-binding protein Alba-like domain-containing protein (Q4Q2T7)
Organism: Leishmania major
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit 2
- RNA-binding protein NOB1
Sequence:
MPPRPSRDEYRRVREGRENRDRPEGAENEVRVTATHGQHSYISYVIAVLNGEDGKTRNDTVKISGMGGAIYNAVNIAEIVKRRIAGLHQITELGSELVRDEYEPIDRTQNPENVVVERKVSTILITLSRNCLDKSNPGYQEPIADSEVTEQERRDPNMSRRGGRGGIRGGRGGSRGGRGGSRGGRGGSRGGRGVAAIDRRDDREN
Protein: Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Q9UAV5)
Organism: Caenorhabditis elegans
Function: Catalyzes the reversible conversion of (S)-malate to oxaloacetate in the cytoplasm where oxaloacetate is used for gluconeogenesis.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Bifunctional glyoxylate cycle protein
- Probable fumarate hydratase, mitochondrial
- Probable citrate synthase, mitochondrial
- Malic enzyme
- Malate dehydrogenase, mitochondrial
- Aspartate aminotransferase
- Aspartate aminotransferase
- Aspartate aminotransferase, cytoplasmic
- Pyruvate carboxylase 1
- Phosphoenolpyruvate carboxykinase
Sequence:
MSAPLRVLVTGAAGQIGYSIVIRIADGTVFGKEQPVELVLLDVPQCSNILEGVVFELQDCALPTLFSVVAVTDEKSAFTGIDYAFLVGAMPRREGMERKDLLAANVKIFKSQGKALAEYAKPTTKVIVVGNPANTNAFIAAKYAAGKIPAKNFSAMTRLDHNRALAQLALKTGTTIGNVKNVIIWGNHSGTQFPDVTHATVNKNGTETDAYAAVGDNAFLQGPFIATVQKRGGVIIEKRKLSSAMSAAKAACDHIHDWHFGTKAGQFVSMAVPSDGSYGIPQGLIFSFPVTIEGGEWKIVQGLSFDDFAKGKIAATTKELEEERDDALKACDDANI
Protein: DNA-binding protein HMf-1 (Archaeal histone A) (P48781)
Organism: Methanothermus fervidus
Function: Binds and compacts DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:2377617}. Chromosome {ECO:0000305|PubMed:2377617, ECO:0000305|PubMed:7809089}.
Interaction partners:
Sequence:
MGELPIAPIGRIIKNAGAERVSDDARIALAKVLEEMGEEIASEAVKLAKHAGRKTIKAEDIELARKMFK