wanglab/gogpt-training-data huggingface dataset:
Protein: NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial (EC 7.1.1.2) (Protein EMBRYO DEFECTIVE 1467) (Q9FGI6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}. Note=Matrix and cytoplasmic side of the mitochondrial inner membrane. {ECO:0000250}.
Interaction partners:
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase iron-sulfur protein 8-B, mitochondrial
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase iron-sulfur protein 2
- NADH dehydrogenase iron-sulfur protein 6
- Probable NADH dehydrogenase 1 alpha subcomplex subunit 5
- NADH dehydrogenase 1 alpha subcomplex subunit 9
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 2
Sequence:
MGLGILASRTIRPASRLLQSQTSNFFLRTIVSKPELQSPESAAVSEPEPPTQILPPRNPVGGARVHFSNPEDAIEVFVDGYAVKVPKGFTVLQACEVAGVDIPRFCYHSRLSIAGNCRMCLVEVEKSPKPVASCAMPALPGMKIKTDTPIAKKAREGVMEFLLMNHPLDCPICDQGGECDLQDQSMAFGSDRGRFTEMKRSVVDKNLGPLVKTVMTRCIQCTRCVRFASEVAGVQDLGILGRGSGEEIGTYVEKLMTSELSGNVIDICPVGALTSKPFAFKARNWELKATETIDVSDAVGSNIRVDSRGPEVMRIIPRLNEDINEEWISDKTRFCYDGLKRQRLSDPMIRDSDGRFKAVSWRDALAVVGDIIHQVKPDEIVGVAGQLSDAESMMVLKDFVNRMGSDNVWCEGTAAGVDADLRYSYLMNTSISGLENADLFLLIGTQPRVEAAMVNARICKTVRASNAKVGYVGPPAEFNYDCKHLGTGPDTLKEIAEGRHPFCTALKNAKNPAIIVGAGLFNRTDKNAILSSVESIAQANNVVRPDWNGLNFLLQYAAQAAALDLGLIQQSAKALESAKFVYLMGADDVNVDKIPKDAFVVYQGHHGDKAVYRANVILPASAFTEKEGTYENTEGFTQQTVPAVPTVGDARDDWKIVRALSEVSGVKLPYNSIEGVRSRIKSVAPNLVHTDEREPAAFGPSLKPECKEAMSTTPFQTVVENFYMTNSITRASKIMAQCSAVLLKKPFV
Protein: Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) (Q13283)
Organism: Homo sapiens (Human)
Function: ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also RIGI-induced type I interferon production probably by helping RIGI at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:20180778, ECO:0000269|PubMed:30510222}. Perikaryon {ECO:0000250|UniProtKB:P97855}. Cytoplasm, Stress granule {ECO:0000269|PubMed:12642610, ECO:0000269|PubMed:17210633, ECO:0000269|PubMed:20180778, ECO:0000269|PubMed:23953116, ECO:0000269|PubMed:27022092, ECO:0000269|PubMed:30404792, ECO:0000269|PubMed:32302570, ECO:0000269|PubMed:32302571, ECO:0000269|PubMed:32302572}. Nucleus {ECO:0000269|PubMed:11604510}. Note=Cytoplasmic in proliferating cells (PubMed:11604510). Cytosolic and partially nuclear in resting cells (PubMed:11604510). Recruited to stress granules in response to arsenite treatment (PubMed:12642610, PubMed:20180778). The unphosphorylated form is recruited to stress granules (PubMed:12642610). HRAS signaling contributes to this process by regulating G3BP dephosphorylation (PubMed:12642610). {ECO:0000269|PubMed:11604510, ECO:0000269|PubMed:12642610, ECO:0000269|PubMed:20180778}.
Interaction partners:
- Caprin-1
- Ubiquitin carboxyl-terminal hydrolase 10
- Cytotoxic granule associated RNA binding protein TIA1
- Nucleolysin TIAR
- Polyadenylate-binding protein 1
- Ras GTPase-activating protein 1
- Eukaryotic translation initiation factor 4 gamma 1
- Ras GTPase-activating protein-binding protein 2
- Eukaryotic translation initiation factor 3 subunit B
- TAR DNA-binding protein 43
Sequence:
MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ
Protein: Mitochondrial outer membrane 72K protein (P72802)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- Sll1251 protein
- Serine/threonine-protein kinase B
- Serine/threonine-protein kinase D
- Serine/threonine-protein kinase C
- Slr2048 protein
- Serine/threonine-protein kinase F
- Sll0837 protein
Sequence:
MLILKNSMASPHPFPWPQRFTVMALTFAWGLSLPVLAQTKSAVQWYNDGVDKLAAQNFSGAIADFTESIKLNDQDADAYYNRGYAKHVLGQYQAAITDYNQAISLNPEFAYALGNRCYAYFLLSQYDKAIQDCSNAIEINPNYADFYVYRGNSQSQLGNETTAIADYNDAIRINAQHANAYYNRALTHNRLKQDQQALADYNQSIQLDPDSAEAYFNRGLTQYRLGDEPKAIADLTKAAELFNAQEKKDMAQKAEAILTQIRAIDA
Protein: Fad3p (A0A1D8PFL5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MSVVEASSSSVVEDSTASNVVQRGNISSFASTTASSNLTTIDTNGKVFKVPDYSIKDILQAIPKHCYERSLIRSLGYVVRDITMMVIIGYVGHTFIPMVQIPEYPSLAFGLRGALWMVQSYCIGLFGFGLWILAHECGHGAFSDYQNINDFIGWILHSYLIVPYFSWKFSHAKHHKATGHLTKDMVFIPYTKEEYLEKNKVEKVADLMEESPIYSFLVLVFQQLGGLQLYLATNATGQVYPGYSKIAKSHYTPTSPVFDKHQYWYIVLSDIGIILAFTTVYQWYKNFGLFNMMINWFVPWLWVNHWLVFVTFLQHTDPTMPHYTSKEWTFARGAAATIDRNFGFVGQHIFHDIIETHVLHHYVSRIPFYNAREATDAIRKVMGEHYRYEGESMWYSLWKCMRMCQFVDDDKEDAKGVMMFRNVNGWGPVKPKD
Protein: Interferon-gamma receptor (Q9QZ62)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MILLVVLMLSAEIGSGALMSTEDPKPPSVPAPTNVLITSYDLNPVVHWKHQNVSQAAVFTVQVKMYPEYWTDACTNIAHHYCNIYKHISYPDSSAWARVKAKVGQRESAYAQSEEFIMCRKGKVGPPGLDIGRKEDQLIVHIFHPKVNVSQETMFGDGNTCYTFDYTVFVKHYRSGEILHTEHSVLKEDCSETLCELNISVSTLNSNYCVSVVGKSSFWQVNTETSKDACIPFLHDDREESIWMLLVAPLLFLTIVVPALVCCYIKKNPFKRKSIMLPKSLLSVVKNATSETKPESKYSLVTSCQPAVLENETVICEEHLSTVTTPDSLEAPEQEELSKGTVATVAEGNTSPETTDSPLTPVQSGHFSLSSSNQSGSCSLTTYHSRDGSDSGLVGTGSSISDSDFLPNNDSETKMADPAPTPVRKALTFSGYDKPHVLVDVPVDGEGKESLIGYRLTGDTQELS
Protein: Phosphodiesterase (Q9Z584)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Interaction partners:
- GGDEF domain-containing protein
- DNA ligase 1] 1)
- Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein
- Integral membrane protein
Sequence:
MEPTESAAAGSRLRLRRMADAWHVSRWLGQRDGGVPSSMTGTRVPQAVGRPHGHPQGHPHGLVDPDGERHLSWPALPAAVVATAAFVLGAGFYRAFSDGHALFPAGTVGWSLAVLSGIVVGHLVMLGRSRWWGGTGSGAALTLAVLLLYGWIPAGMVSLTVVVLVGIARRGRWRQGVLHGAVDILGIAAGAVVLGVCGSVPSVERPWDPETWGVYAAPKVVLVAVAYLAVTRALLWYIQTPRPGLPTAARTALVRHGLVAVALLGIAPLICVVAVAKPLLLPLFAIPLIALDSTLWIARARAEEQLRDPLTGLPNRQWLLERTWTALDDAERIGARAALMLIDLDRFRSVNDTLGHLAGDRLLLQTADRLRQALPRGAEAARLGGDEFAVLLPVADSTTSATRIARSLVGALSSPMDLDGLTLVLEASAGVAVFPDHALDAEGLLRRADVAMYQAKRDRTGVEVYESKRDSNTPDRLGLLGDLRRALDAHEVQLHYQPKVRFDGQVAGLEALVRWVHPERGKVPPDEFIAIAESSGLMPHLTEYVLETALGQVARWRAQGLFVPVAVNVSPRDVHTPGFAGSVAARLARHGVPAGALQLEITEHVLLEDPQRAADTLNALTGHGVKMSLDDFGTGYSSLVHLRRLPVSELKIDRSFVARLAIDNEDAEIVRCTVDLAHSLGLLVVAEGVEDDETWERLRDLGCDAVQGWLVAAAMPPEETTAWLLARGSRGWVRAAAALPAAASDE
Protein: Cation-transporting ATPase 5 (EC 7.2.2.-) (O14022)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays a role in regulating calcium and manganese homeostasis responsible for cell cycle progression.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:19168988}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Probable cation-transporting ATPase C1672.11c
- Manganese transporter pdt1
Sequence:
MDSIELKQLVPENDSEPGTPRQLLFQHYDISNEETIGIKPFKSIPAKVYILRVTEILTLGLLHLILTWLPEFRLKWIEAPCSNEDVEFVAISDPSGTSSIEKVSSICLKNDIQTSSFVLPSGKTRYFEYKKLRFYLEPLNLQWVLMPLETSAYSLVTSTPAYIQNGLDTFTIAKLRQVYGSNSLVSTKKSIVTILLNEVLHPFYLFQAVSVLIWLCDSFVFYSCCIVFISSYSIFLSVKESKESENRIHSIIGAPQPVTVIRNQVKQTVLADDLVIGDLLYFSNLDLKTCPVDGILFSSSCLLDESMVTGESVPARKFPLEDNSLDSWMIASCNIFSPHLIHAGTKFLKIDSTPSTPCLISVVRTGFRSNKGQLIRNLLYPNLRPSQLYLDSMSFLKTMAILSFVSIVFIAIYLNLYNASFGHVVLRSLDVLTILVPPALPATLSVGIANSIARLSRALIYTTSPESIHNAGCLSTFVFDKTGTLTENSVQLSCVYVKSGSNGLLKQVDADSLSLDSTKLNAHAYRVATCSQSLELVGNELVGDPLEVTLFTQFNGTFCATIRASNTPHPPLFSVSNSFDGPSQIFSIYKALEFDPVLRRMSVICSTSTERSLMLFTKGAPESILAISSQQSIPSNVQEVIHTLSSKGFRIIAFASKNLITPLQELIHLSRSTLESNVTFQGLFVLESPLRESSKDVISSLLRSKMEVSICSGDSLFTSVFVAKHCGALDSCNFIYTAELADSGDDCPQIHFEKIDLQTQNFQPIPDGFSLKDVILEKDSSLCMDGKLLQRLLTMLSFNEIKILLSKLRVLARMSPFDKATYVELCQKYGCKVGFCGDGANDCIALKQADVGVSLSDSEACAAASFVSKKKSIKDVFNVLLEGRCSLILSHRCFQYMVLCAIVQFSGVFFLYLKNYNFNDNQFLFMDLLIIFPLSAAMSYFDPAQNLTSNRPNSTLFGKGRVKDLGIQSVLIWLSHGLLTLILHELNWVELPEWQLEKSNTKNVLVTSIFLLSSLQYLGICIGINQSSEFLSPIWKKKTYVCLCTTIGLCNIYLCFANENHIISRCLQITRLPTLYRFIILFMGVISCCLTSILNM
Protein: Transforming growth factor-beta-induced protein ig-h3 (D4A8G5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Integrin beta-3
Sequence:
MALLVRLLPLALALSLGFTGTLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNKKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGIVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWSSLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDELKHGMALTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTVTNNIQQIIEIEDTFETLRAAVAASGLNTVLEGDGQFTLLAPTNEAFEKIPAETLNRILGDPEALRDLLNNHILKTAMCAEAIVAGMAMETLGGTTLEVGCSGDMLTINGKAVISNKDILATNGVIHFIDELLIPDSAKTLLELASESDVSTAIDLLRQAGLSTHLSGKEQLTFLAPLNSVFKDGVPRIDGQMKTLLLNHMVKGQLASKYLYSGQTLDTLGGKKLRVFVYRNSLCIENSCIAAHDKKGRYGTLFTMDRMLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLMETLNREGVYTVFAPTNEAFQAMPPEELNKLLANAKELTNILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSSKNNVVSVNKEPVAETDIMATNGVVYAINTVLQPPANRPQERGEELADSALEIFKKASAYSRVCPLSISGY
Protein: Uncharacterized protein Rv1352 (P9WM15)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized protein Rv1351
- Possible oxidoreductase
- Conserved protein
- Conserved protein
- Conserved protein
- Secreted protein
Sequence:
MARTLALRASAGLVAGMAMAAITLAPGARAETGEQFPGDGVFLVGTDIAPGTYRTEGPSNPLILVFGRVSELSTCSWSTHSAPEVSNENIVDTNTSMGPMSVVIPPTVAAFQTHNCKLWMRIS
Protein: Extracellular glycosidase CRH11 (EC 3.2.-.-) (Congo red hypersensitive protein 11) (Q5AFA2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Extracellular glycosidase which plays an important role in fungal pathogenesis. Involved in cell wall assembly and regeneration, filamentation, and adherence to host cells.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:15302828, ECO:0000269|PubMed:16455273, ECO:0000269|PubMed:18712765, ECO:0000269|PubMed:19555771, ECO:0000269|PubMed:20864472, ECO:0000269|PubMed:21602216, ECO:0000269|PubMed:23243062}. Membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Interaction partners:
- pH-responsive protein 1
- pH-responsive protein 2
- Cell surface GPI-anchored protein ECM33
- Polyadenylate-binding protein, cytoplasmic and nuclear
- RRM domain-containing protein
Sequence:
MKFTTLATIASTLLFAANANADTCNPLKSSDCSPVPALGSSFLEKFDNGLGPHFESLKKQGTIDSGSNGLSLTMKKRFDNPSFKSNFYIMFGRVEVVLKGAEGKGIVSSFYLQSDDLDEIDIEMFGGDPYQWQSNYFIKGNTATYDRGGYHDIANPLKDYHTYVIDWTKDAVTWSVDGSVIRTIPKDNAQGFPQSPMAIYAGIWAGGDPSNQPGTIDWAGGITDYSQAPFTMGIKSVLVADYSSGKQYSYSDQSGSWESIKADGGKVNGRYDQAQDDIKKLESGQSVDSNDSSSSPSASSSDSSSTSSASSSSSSSSPSSTTSSSSSSSSSSSSSSSSSSEKSNAVPSASVIVFIGTKGGDKTTVTSSSGVSVPTSASVSTAAGTTSGSANSAPASAASSTASTVFISTGDAAPSSSASEKPSVSTTENNGAVSVAKTTSLFGFVALIGFLFV
Protein: Cytochrome c oxidase subunit 7A1, mitochondrial (Cytochrome c oxidase subunit VIIa-heart) (Cytochrome c oxidase subunit VIIa-H) (Cytochrome c oxidase subunit VIIa-muscle) (Cytochrome c oxidase subunit VIIa-M) (P56392)
Organism: Mus musculus (Mouse)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P07470}; Single-pass membrane protein {ECO:0000250|UniProtKB:P07470}.
Interaction partners:
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome b-c1 complex subunit 10
- Cytochrome c oxidase subunit 5B, mitochondrial
- Cytochrome c oxidase subunit 8B, mitochondrial
- Cytochrome c oxidase subunit 6B1
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome b-c1 complex subunit 8
- Cytochrome c oxidase subunit 6A2, mitochondrial
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Sequence:
MRALRVSQALVRSFSSSTRSHLENRVAEKQKLFQADNDLPVHLKGGGMDNVLYRLTMTLTLGGTAYCLYCLGWASFPHKK
Protein: Possible osmoprotectant (Glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter ProZ (O69722)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Possible osmoprotectant binding lipoprotein ProX
- ABC-type quaternary amine transporter
- Possible osmoprotectant transport integral membrane protein ABC transporter ProW
- Conserved protein
- MgtC/SapB family protein
- Probable lipoprotein LpqZ
- Uncharacterized membrane protein Rv3760
Sequence:
MNFLQQALSYLLTASNWTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRALPTLGVLLLGVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNALPLMLGGLRSATLQVVATATVAAYASLGGLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAGGGHALR
Protein: Small ribosomal subunit protein uS5z (40S ribosomal protein S2-1) (Q8L8Y0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein eS26z
- Small ribosomal subunit protein eS26y
- Small ribosomal subunit protein eS26x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein uS3x
- Small ribosomal subunit protein uS3z
- Small ribosomal subunit protein uS3y
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein eS1y
- Small ribosomal subunit protein eS1z
Sequence:
MAERGGEGGAERGGDRGDFGRGFGGGRGGGRGRDRGPRGRGRRGGRASEETKWVPVTKLGRLVADNKITKLEQIYLHSLPVKEYQIIDHLVGPTLKDEVMKIMPVQKQTRAGQRTRFKAFVVVGDGNGHVGLGVKCSKEVATAIRGAIILAKLSVVPVRRGYWGNKIGKPHTVPCKVTGKCGSVTVRMVPAPRGSGIVAARVPKKVLQFAGIDDVFTSSRGSTKTLGNFVKATFDCLQKTYGFLTPEFWKETRFSRSPYQEHTDFLSTKAVSATKVITEGEDQA
Protein: Calsequestrin (C0KTH8)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Sarcoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004564}.
Interaction partners:
Sequence:
MLALWLLLLPCLSLLPLVQTEKGLEFPRYDGKDRAIDINNKNHQKAMKKYTMMCLLYHKPIPDGKELQKQHLMTEMVLELAAQVMEEKEIGFGMVDSHKDTKVAKKLGLVEEGSVYVFKADRVIEFDGMLSADTLVEFLLDLLEEPVEVIGNALELRAFDRMEEDIRLIGYFKNEDSEHYSAFKEAAEQFQPYIKFFATFEKAVAKELTLKMNEVDFYEPFMEEPVTLPDRPNSEEEIVAFVTEHRRPTLRKLRAEDMFETWEDVVEGSHIVAFAEEEDPDGYEFLELLKEVARDNTHHPGLSIIWIDPDDFPLLIPYWEKTFQVDLFKPQIGVVNVTDADSIWLEMEEQDLLTAQKLADWTENVLSGKVNTEDDDNDDDEEEEDDDDDSDDDSDDSDDSDDEEDEDDDD
Protein: Polygalacturonase (A4GXB4)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MHRASLPGDGLPDVVIRGENGTIDGQGGIWWNMWRQGNLPFTRPNLVEFMNSRGIIISNVIFKNSPFWNIPPVYCSNVVIRYVTILAPTDSPNTDGIDPDSSSNVCIEDSFISTGDDLVAVKSGWDEYGIGYGRPSSHITIRRVTGSSPFAGIAVGSETSGGVEHVLAENIVIYNSGIGVNIKTNIGRGGFIKNITVSPVFMENVRTGIKIASHPAITR
Protein: ABC transporter A family member 10 (ABC transporter ABCA.10) (Q54R52)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MTNNCKITFKNQLKALLGKAILLKKKKRKETITEFTQGIQYIIVLVILHYTIPNVITLNTYSPVGLGYPTSGFPLCYVSNVPFNQTSNLHLLLNSTQLPISQIVQFPNEQSLIDSYKSNPQSITYGISFNNIDYQNNILDYNILLNSTFQNTQLISIVQNLFLSTFAEIKGITTTTTTTLSSIEEFPNLTSSVSVSSYLYVIYLPLLFLFSLQQLLVTSVTERKNHIKEVMKVMGLKELVYWVTIIIVQTITNVINILLVMVVLYFTKTLTTSLNPVMLFLQFLLYSFSMVAIGIILSNLVDTPKTASAISSFLLLILVGVSCFYQFYLKSKTSSSWLRSILFLFSPCAFGEFLYKMGNDQQMMLTTNWSDPQVKISFLFLIIDIFLYFTIAWYITELYKDNTDENSITKSFTFFLSLSYWKSIFNLRSSSSSSSLPLLNNNNNCNNNNTSPSSSSSSQSSPLNKPLLSGDSDDDENDIGIRLVNLKKTYKNPITKETVNAVNDVSYTIKKGTILALLGQNGSGKTSTIGMLNGMRSPSSGDAFINGLSIKYDMDKIRENGIGLCHQSNILYDEFTCAEHIALYSRLKGLFVDGGGANGDNKRIMMDNFIMESLGEVNLVDKKDTQSIKLSGGMKRRLCLAISLIGNPSILLLDEPSSGLDSLSQHMICELLQRKKPNKTIILTTHNLDSAELLGDKICIMTSGKVKAMGSSLELKNQFNLGYILTIVYDKSLSLLQPPNINQQFESFFFNKFNDSTQSKQNLKNIQSFYNIFNNNNNENNSNNSDGSSSSSDSSSSKDVLLNIKNNNNNNNNNEERGFSSGQRDLELEYSLTHQSTDVITEFLEELESRQDEFKIKRISMSMTTLDEVFLKVSEEETINKNKQPTS
Protein: Probable LRR receptor-like serine/threonine-protein kinase At4g36180 (EC 2.7.11.1) (C0LGS2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000305|PubMed:17644812}; Single-pass type I membrane protein {ECO:0000305|PubMed:17644812}.
Interaction partners:
- Proline-rich family protein
- Plant invertase/pectin methylesterase inhibitor superfamily protein
- Putative expansin-A17
- Polygalacturonase ADPG2
- Endo-1,4-beta-xylanase 5
- Berberine bridge enzyme-like 26
- UPF0496 protein At3g28300
Sequence:
MAMDISLFFIFLVIYAPLVSYADESQAEIDALTAFKLNLHDPLGALTSWDPSTPAAPCDWRGVGCTNHRVTEIRLPRLQLSGRISDRISGLRMLRKLSLRSNSFNGTIPTSLAYCTRLLSVFLQYNSLSGKLPPAMRNLTSLEVFNVAGNRLSGEIPVGLPSSLQFLDISSNTFSGQIPSGLANLTQLQLLNLSYNQLTGEIPASLGNLQSLQYLWLDFNLLQGTLPSAISNCSSLVHLSASENEIGGVIPAAYGALPKLEVLSLSNNNFSGTVPFSLFCNTSLTIVQLGFNAFSDIVRPETTANCRTGLQVLDLQENRISGRFPLWLTNILSLKNLDVSGNLFSGEIPPDIGNLKRLEELKLANNSLTGEIPVEIKQCGSLDVLDFEGNSLKGQIPEFLGYMKALKVLSLGRNSFSGYVPSSMVNLQQLERLNLGENNLNGSFPVELMALTSLSELDLSGNRFSGAVPVSISNLSNLSFLNLSGNGFSGEIPASVGNLFKLTALDLSKQNMSGEVPVELSGLPNVQVIALQGNNFSGVVPEGFSSLVSLRYVNLSSNSFSGEIPQTFGFLRLLVSLSLSDNHISGSIPPEIGNCSALEVLELRSNRLMGHIPADLSRLPRLKVLDLGQNNLSGEIPPEISQSSSLNSLSLDHNHLSGVIPGSFSGLSNLTKMDLSVNNLTGEIPASLALISSNLVYFNVSSNNLKGEIPASLGSRINNTSEFSGNTELCGKPLNRRCESSTAEGKKKKRKMILMIVMAAIGAFLLSLFCCFYVYTLLKWRKKLKQQSTTGEKKRSPGRTSAGSRVRSSTSRSSTENGEPKLVMFNNKITLAETIEATRQFDEENVLSRTRYGLLFKANYNDGMVLSIRRLPNGSLLNENLFKKEAEVLGKVKHRNITVLRGYYAGPPDLRLLVYDYMPNGNLSTLLQEASHQDGHVLNWPMRHLIALGIARGLGFLHQSNMVHGDIKPQNVLFDADFEAHISDFGLDRLTIRSPSRSAVTANTIGTLGYVSPEATLSGEITRESDIYSFGIVLLEILTGKRPVMFTQDEDIVKWVKKQLQRGQVTELLEPGLLELDPESSEWEEFLLGIKVGLLCTATDPLDRPTMSDVVFMLEGCRVGPDVPSSADPTSQPSPA
Protein: Acyl-coenzyme A thioesterase THEM5 (Acyl-CoA thioesterase THEM5) (EC 3.1.2.2) (Acyl-coenzyme A thioesterase 15) (Thioesterase superfamily member 5) (Q8N1Q8)
Organism: Homo sapiens (Human)
Function: Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:22586271}.
Interaction partners:
- Acyl-coenzyme A thioesterase THEM4
- Cytosolic acyl coenzyme A thioester hydrolase
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Acyl-coenzyme A thioesterase 1
- Peroxisomal succinyl-coenzyme A thioesterase
- Very-long-chain enoyl-CoA reductase
Sequence:
MIRRCFQVAARLGHHRGLLEAPRILPRLNPASAFGSSTDSMFSRFLPEKTDLKDYALPNASWCSDMLSLYQEFLEKTKSSGWIKLPSFKSNRDHIRGLKLPSGLAVSSDKGDCRIFTRCIQVEGQGFEYVIFFQPTQKKSVCLFQPGSYLEGPPGFAHGGSLAAMMDETFSKTAFLAGEGLFTLSLNIRFKNLIPVDSLVVMDVELDKIEDQKLYMSCIAHSRDQQTVYAKSSGVFLQLQLEEESPQ
Protein: Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR) (Q9Y5L0)
Organism: Homo sapiens (Human)
Function: Importin, which transports target proteins into the nucleus. Specifically mediates the nuclear import of splicing factor serine/arginine (SR) proteins, such as RBM4, SFRS1 and SFRS2, by recognizing phosphorylated SR domains. Also mediates the nuclear import of serine/arginine (SR) protein CPSF6, independently of CPSF6 phosphorylation. The nuclear import process is regulated by the small GTPase Ran that partitions between cytoplasm and nucleus in the predominantly GDP- and GTP-bound form, respectively. Importin associates with target cargo proteins in the cytoplasm, and the competitive binding of GTP-bound Ran induces the release of cargos in the nucleus.
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:31192305, ECO:0000305|PubMed:10713112, ECO:0000305|PubMed:23543484}. Cytoplasm {ECO:0000269|PubMed:10713112}. Note=Localizes to the nuclear envelope and annulate lamellae, which consists in stacks of endoplasmic reticulum membranes containing a high density of nuclear pores. {ECO:0000269|PubMed:31192305}.
Interaction partners:
- Serine/arginine-rich splicing factor 1
- Transportin-1
- GTP-binding nuclear protein Ran
- Nuclear pore complex protein Nup153
- Cleavage and polyadenylation specificity factor subunit 6
- Importin-7
- E3 SUMO-protein ligase RanBP2
- Bifunctional glutamate/proline--tRNA ligase
- Serine/arginine-rich splicing factor 2
- Vacuolar protein sorting-associated protein 53 homolog
Sequence:
MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQDVESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSPVIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTDEKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIENVETNLPLAMQLFQGVLTLETAYHMAVAREDLDKVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHGIFKAYIQRLLHALARHCQLEPDHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLKEGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVRLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKPLASAAAKAIHNICSVCRDHMAQHFNGLLEIARSLDSFLLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQEPSNGISSDPTVFLDRLAVIFRHTNPIVENGQTHPCQKVIQEIWPVLSETLNKHRADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEEGCRQGLLDMLQALCIPTFQLLEQQNGLQNHPDTVDDLFRLATRFIQRSPVTLLRSQVVIPILQWAIASTTLDHRDANCSVMRFLRDLIHTGVANDHEEDFELRKELIGQVMNQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDRPTFCRWLENSLKGLPKETTVGAVTVTHKQLTDFHKQVTSAEECKQVCWALRDFTRLFR