wanglab/gogpt-training-data huggingface dataset:
Protein: Eukaryotic translation initiation factor 4E-3 (eIF-4E-3) (eIF4E-3) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein) (O61955)
Organism: Caenorhabditis elegans
Function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. All 5 eIF4E proteins bind monomethyl cap structures. Only ife-1, ife-2 and ife-5 bind trimethyl cap structures which result from trans-splicing. Translation of trimethyl cap structure mRNAs may be regulated by intracellular redox state; disulfide bonds change the width and depth of the cap-binding cavity determining selectivity to mRNA caps. Ife-3 is essential for viability. Component of the pid-1 and tost-1 variants of the PETISCO complexes, which have roles in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) and embryogenesis, respectively. Within the pid-1 variant of the PETISCO complex binds to capped 21U-RNA precursor molecules, possibly playing a role in the processing of the 5' end of the molecules to promote binding of other complex components such as pid-3. However, it is not essential for the biogenesis of 21U-RNAs by itself. Within the tost-1 variant of the PETISCO complex binds to splice leader SL1 RNA fragments to possibly play a role in their processing.
Subcellular location: Cytoplasmic granule {ECO:0000269|PubMed:31147388}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:31147388, ECO:0000269|PubMed:31216475}. Note=Localizes to cytoplasmic granules in early embryos (PubMed:31147388). Localizes to puncta in the perinuclear region in the germline syncytium (PubMed:31147388, PubMed:31216475). {ECO:0000269|PubMed:31147388, ECO:0000269|PubMed:31216475}.
Interaction partners:
- Translational repressor ifet-1
- MIF4G domain-containing protein
- Eukaryotic translation initiation factor 4E-binding protein Mextli homolog
- Embryonic developmental protein tofu-6
- Cytoplasmic FMR1-interacting protein homolog
- Protein pid-3
- Enhancer of rudimentary homolog 2
- Eukaryotic initiation factor 4A
- Prion-like-
- Protein tost-1
Sequence:
MSTSVAENKALSASGDVNASDASVPPELLTRHPLQNRWALWYLKADRNKEWEDCLKMVSLFDTVEDFWSLYNHIQSAGGLNWGSDYYLFKEGIKPMWEDVNNVQGGRWLVVVDKQKLQRRTQLLDHYWLELLMAIVGEQFDEYGDYICGAVVNVRQKGDKVSLWTRDATRDDVNLRIGQVLKQKLSIPDTEILRYEVHKDSSARTSSTVKPRICLPAKDPAPVKEKGPAATTSPSNPGTEATGTSPATPTP
Protein: Small ribosomal subunit protein uS4 (40S ribosomal protein 1024) (40S ribosomal protein S9) (Vegetative-specific protein V12) (P14132)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P46781}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P46781}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000250|UniProtKB:P46781}.
Interaction partners:
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein eS30
- Large ribosomal subunit protein eL21
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS8
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein uS17
Sequence:
MSSNYSKTSHTPRRPFEKERIDAELKVVGEFGLKNKNEVWRVQYALAKIRKAARELLVLDEKDPKRIFEGSALLRRLHKLGVMEESKNKLDYILNLKVQDFMERRLQTLVFKNGLAKSIHHARVLIKGRHIRVGKQLVNVPSFLVRVESQKHLGLASTSPLAGGRPGRRARKMAKNNSSKGEEEN
Protein: Zinc finger protein 431 (Zinc finger protein 932) (E9QAG8)
Organism: Mus musculus (Mouse)
Function: Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1.
Subcellular location: Nucleus {ECO:0000269|PubMed:21177534}.
Interaction partners:
Sequence:
MVDALTYDDVYVNFTQEEWALLNPSQKSLYKDVMLETYRNLNAVGYNWEDSNIEEHCESSRRHGRHERNHTGEKPYEGIQYGEAFVHHSSLQMRKIIHTGEKRYKCNQCDKAYSRHSILQIHKRTHSGEKPYECNQCGKAFTQHSHLKIHMVTHTGEKPYKCDQCGKAFAFHSTLQVHKRTHTGEKPYECNQCSKAFAHHCHLRVHKRIHTGEKPYKCDQCGKAFVGQNDLKRHERVHTGEKPYKCNECGKAFVCNASLRTHKTTHTGVKPYECKQCTKSFASHGQLQKHERIHTGEKPYKCDQCGKAFASHDKFQKHERIHIGEKPYKCKQCTKSFASHDKLQKHERIHTGEKPYECKQCTKSFASHNKLQKHERIHTGEKPYKCDQCNKAFVYESYLQVHKKTHTGEKPYKCNECGKAFARHSHLKVHKITHTGEKPYKCNQCGKALAYHSTLQVHQRTHTGEKPYECEQCGKAFANQSYFQVHKRIHTGEKPYKCDQCGKAFVGSSDLKRHERVHTGRETLQM
Protein: Protein chiffon (Q9NK54)
Organism: Drosophila melanogaster (Fruit fly)
Function: May be involved in initiation of DNA replication; activation of the chorion gene origins. May have a role in eye and thoracic bristle development.
Interaction partners:
- non-specific serine/threonine protein kinase Cdc7
- non-specific serine/threonine protein kinase
- Origin recognition complex subunit 2
- DNA replication licensing factor Mcm2
- Origin recognition complex subunit 4
- DNA replication licensing factor Mcm5
- Origin recognition complex subunit 6
- DNA replication licensing factor Mcm3
- DNA replication licensing factor MCM4
- DNA replication licensing factor Mcm7
Sequence:
MQPQSDKQSASRLATTTSHSTAAASATAATPPKVKVIKSKRPLCHFKFYLDICDHQLAKRIESDIKALGGHLEFFLSDDITHFVTDKPEVIGGTSGTPGTPSTPGTPTSHYQQNDGSARKPNQRQSRADAILSRVRRSTVGVVNSGNSTPTTSLKRSYTIWQTDYAQRFIKRIQTELKQYLEGKKEGGGGSTSASPHHIQLKKQYVKIESVKRNYRPYYHLIKQPDDWPKIDLSSEDGAFRLLTKSKTKDKEHSMTRKPLGSRTSQKDKQAAGEAKPLQHPSLQELKKQSAIPNSPRSNCREPIDSSEKQGGVCEICKLEYDILNIHLQSKDHELFAKNSDNFLALDTLIQSSADVNRFLEEEPVESELDMDVDESLSNEELQSPRQRPSPALREKSKRITKGKHSSEKFQGVAVASPQTPFPGAKKVQGNSPGSLSELQRQEHPTTAAATPTTNSGRRKTQNSGLSPPKRAMLPPSSIYKVVETREECATPPRGRGRPPNQVDSPSLIVKFQKIRQTELQRLNGEAENFMFPRTAVPTTRSSSELPTDVDRQTTSDVRGRYSISSASLDTSTSEAETKESSGLPTSIRKRAQAVGRRRKVGGAAAQDVFQRQLSTGSSSSNSNQQRFPSAPIQPEEGPQPQPKPQLKIKIKQEQLVATRKSSRTATAIVTAATASSHQQQQLRQTTCRKMANKLEDRMGELVKPKIKIKKEVIEEQKVKELEDLEEILDKELDEEVDSSCSSGSDEDYIAGSQRRITAAPRKSTDTREQRAARRLSRLTINRSAGELELTEVKTSPSKSRTKIQKPSSPTKNKVKQTKAVPPAIDLFFDCSKSERLREMQYTFESLPSGELWNRVFLRQDAGEENYYTYYGSTNYRKLPYEMGPIPMAKTLPAHSCALCREASEVKQDKGEQIKLEDQKPAPKKEVKKEEEVQSSSSSATYKNKKLHLLQRYQQEQEQLQQLEGNSLATAGAKCDSKASTPELLEREFASGSMGDRVQLIERVRSTSSSSCSNSQRSGITCRNKQLARIAELPPRKSPREHASTLALVSCIIRQRQDSQSKTNSEAEEPPPPVAAPKLKTPIKQEPVAPSSPRTTRSQAATPVEELRFATEISETVKRMRRGQNKYDHSPPAPVPTPATSSPVRSRRLTPAARNQSQIYSRRLEFATSQRESSASALLGKRKRRVNPSVAGTVRPTTQNLPGTGAYRGVRKLPSKKGLLEYEMETCALKALDQARQYCNPGFVAWQLDKYLELAGKEYDIEFDQISPEVESEGREERLVNTPQTPPPTDCFTSEFDLCDLIMGSAGSGDDDEDVSRGNPPGSGRRMSNLNLYASYYRKRKSLKSNRTGWPKAQRRRNAGGLGGSRALPDERINFQKMGLAELHPIKQEPMETEEEQTTTTTTTTTTSATRGNLLSKDDEDDEGGGNSPSGGSPADDKQNSREDAVMTPPATDVDEQAEPQADEMESLPDEDETMADSVDQQQDVEAEIEATDADVEEEEEEEDEDEDVFEDAYEEQDMGIQKTEPHEKRARIPSISVTTPPEDSSQGKKLLLTLHNGQRLQATSTPSTGQVQQHQRRTPQLNGSLGSCISPSEKLGDNSDIFTVSSDGLDTDLDLSNTQAGDSHEHCPHQTTPKRKFDISKYAPPNSGKAASSCAAEAATAAVKSLAISQFLKKETCASSSSMRNAWRRTQRRAISAACISAAPSARVPN
Protein: Beta-glucosidase 8 (AtBGLU8) (EC 3.2.1.21) (Q67XN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F-box protein At5g03100
- Transmembrane protein, putative
- At4g12735
- Glucan endo-1,3-beta-glucosidase 8
- Plant invertase/pectin methylesterase inhibitor superfamily protein
- Probable serine/threonine-protein kinase PBL23
- Heavy metal-associated isoprenylated plant protein 36
- Protein STRICTOSIDINE SYNTHASE-LIKE 3
- Beta-glucosidase 44
- Probable inactive beta-glucosidase 25
Sequence:
MKHFNLLSIILVIVLATSYIDAFTRNDFPEDFLFGAGTSAYQWEGAANEDGRTPSVWDTTSHCYNGSNGDIACDGYHKYKEDVKLMAEMGLESFRFSISWSRLIPNGRGRINPKGLLFYKNLIKELRSHGIEPHVTLYHYDLPQSLEDEYGGWINHKIIEDFTAFADVCFREFGEDVKLWTTINEATIFAFAFYGKDVRYGNCTTGNYCMETYIAGHNMLLAHASASNLYKLKYKSKQRGSIGLSIFALGLTPYTNSKDDEIATQRAKAFLYGWMLKPLVFGDYPDEMKRTLGSRLPVFSEEESEQVKGSSDFVGIIHYTTVYVTNQPAPYIFPSSTNKDFFTDMGAYIISTGNSSSFVFDAVPWGLEGVLQHIKHRYNNPPIYILENGSPMKHDSMLQDTPRVEYIQAYIGAVLNAIKSGSDTRGYFVWSLIDLFEVQVGYKSSFGMYYVNFSDPGRKRSPKLSASWYTGFLNGTIDVASQDMTQLQRNFSGSSSL
Protein: Interferon alpha/beta receptor 2 (Type I interferon receptor 2) (V5JFY4)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Together with IFNAR1, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response. Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another. The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors (STAT1, STAT2 and STAT). STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes (By similarity).
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000305|PubMed:24244163}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000305|PubMed:24244163}.
Interaction partners:
Sequence:
MGPWTLLLLHLPLVVSMLPAPTNVSIVSFNLEHTLTWLPGPETPDNTHFTVQSLRKNSWQLVKGCARLKTRQSCDLTNTFKDPFYHYKARVQAITTTQKSNRSLSMLFYPLTDTLLGPPVVSVSGCGNCPLLQVTPPTSRGLQRSLSPTQLYYRQFTCKVRRTRDGSQFSMWVTSTEKTVIGYLEPGAEYCVTVTPSTSFNPHSVPSEPHCAFTSPTAANTVPVVLSVLCAFSLLVVLLCGIVVYSGRLLCMHKPLPKTLSSVPLCGG
Protein: Cytochrome b-c1 complex subunit 1, mitochondrial (Ubiquinol-cytochrome-c reductase complex core protein 1) (P98080)
Organism: Caenorhabditis elegans
Subcellular location: Mitochondrion matrix {ECO:0000305}.
Interaction partners:
- Cytochrome c domain-containing protein
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome b-c1 complex subunit 7
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Cytochrome c oxidase subunit 4
- Cytochrome c oxidase subunit 6A, mitochondrial
- COX5B-domain-containing protein
- NADH-ubiquinone oxidoreductase 75 kDa subunit
Sequence:
MALRLAVSSALRPALNSQVRNASSAVSVKDVLASAPQAEVTTLKNGFRVVTEDNGSATATVGVWIETGSRFENEKNNGVAHFLERLIHKGTGKRASAALESELNAIGAKLNSFTERDQTAVFVQAGAQDVEKVVDILADVLRNSKLEASTIDTERVNLLKELEASDDYHQLVLFDMLHAAGFQGTPLALSVLGTSESIPNISAQQLKEWQEDHYRPVRMVLSAVGGGVSNVSSLADKYFGDLSNEYPRKVPQVDGTRFTGSEYRYRNDNVPHMYAAFAVEGVGYAHKDALALQIANQFIGQWDVTHATSRTAASRLVQKIGHDHGVHNLQHFNINYKDTGLFGIYFVADAHDLNDTSGIMKSVAHEWKHLASAATEEEVAMAKNQFRTNLYQNLETNTQKAGFNAKELLYTGNLRQLSELEAQIQKVDAGAVREAISRHVYDRDLAAVGVGRTEAFPNYALTRAGMSWWRM
Protein: Aldehyde dehydrogenase family 3 member H1 (AtALDH4) (Ath-ALDH4) (EC 1.2.1.3) (Q70DU8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long-chain saturated aldehydes are preferred substrates, while the short-chain aldehyde propanal is a weak substrate. Is strictely NAD(+) specific.
Interaction partners:
- Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal
- Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial
- Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial
- Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial
- Polyamine oxidase 3
- Acetate/butyrate--CoA ligase AAE7, peroxisomal
- Probable polyamine oxidase 4
- Polyamine oxidase 1
- Polyamine oxidase 2
- Aldehyde dehydrogenase family 7 member B4
Sequence:
MAAKKVFGSAEASNLVTELRRSFDDGVTRGYEWRVTQLKKLMIICDNHEPEIVAALRDDLGKPELESSVYEVSLLRNSIKLALKQLKNWMAPEKAKTSLTTFPASAEIVSEPLGVVLVISAWNYPFLLSIDPVIGAISAGNAVVLKPSELAPASSALLTKLLEQYLDPSAVRVVEGAVTETSALLEQKWDKIFYTGSSKIGRVIMAAAAKHLTPVVLELGGKSPVVVDSDTDLKVTVRRIIVGKWGCNNGQACVSPDYILTTKEYAPKLIDAMKLELEKFYGKNPIESKDMSRIVNSNHFDRLSKLLDEKEVSDKIVYGGEKDRENLKIAPTILLDVPLDSLIMSEEIFGPLLPILTLNNLEESFDVIRSRPKPLAAYLFTHNKKLKERFAATVSAGGIVVNDIAVHLALHTLPFGGVGESGMGAYHGKFSFDAFSHKKAVLYRSLFGDSAVRYPPYSRGKLRLLKALVDSNIFDLFKVLLGLA
Protein: Probable transmembrane alkane 1-monooxygenase AlkB (Alkane 1-hydroxylase) (Lauric acid omega-hydroxylase) (Omega-hydroxylase) (Fatty acid omega-hydroxylase) (Alkane hydroxylase-rubredoxin) (O05895)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004429}.
Interaction partners:
- Rubredoxin
- Rubredoxin
- HTH-type transcriptional regulator AlkX
- Probable alcohol dehydrogenase AdhA
- Alcohol dehydrogenase B
- Probable zinc-type alcohol dehydrogenase
- Probable aldehyde dehydrogenase NAD dependent AldA
- Probable alcohol dehydrogenase adh
- Aldehyde dehydrogenase
- Probable aldehyde dehydrogenase
Sequence:
MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGMNQLGWHAAAQVPLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDKYYRYCTYIYIPFQYLSVVLGAYLFTAANLSWLGFDGALSWAGKLGVALSVGVLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRVSTPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRLGVSPWNPMTYLRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLEHYGLLRQKSANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANPTRRYQTLRSMAGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDITRVNLHPRVREKALARYGASA
Protein: Teashirt homolog 3 (Zinc finger protein 537) (Q63HK5)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity). Involved in the modulation of glutamatergic synaptic transmission and long-term synaptic potentiation (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19343227}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with APBB1 in axonal growth cone (By similarity). Colocalizes with APBB1 in the nucleus. {ECO:0000250}.
Interaction partners:
Sequence:
MPRRKQQAPRRAAAYVSEELKAAALVDEGLDPEEHTADGEPSAKYMCPEKELARACPSYQNSPAAEFSCHEMDSESHISETSDRMADFESGSIKNEEETKEVTVPLEDTTVSDSLEQMKAVYNNFLSNSYWSNLNLNLHQPSSEKNNGSSSSSSSSSSSCGSGSFDWHQSAMAKTLQQVSQSRMLPEPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNHETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPATRKKASLELELPSSPDSTGGTPKATISDTNDALQKNSNPYITPNNRYGHQNGASYAWHFEARKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAMKKGKPIVETPVTPTITTLLDEKVQSVPLAATTFTSPSNTPASISPKLNVEVKKEVDKEKAVTDEKPKQKDKPGEEEEKCDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTKNQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPDGKLSPPKRATPSPCSSEVGEPIKMEASSDGGFRSQENSPSPPRDGCKDGSPLAEPVENGKELVKPLASSLSGSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPPLQSKKADHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSVLLSPTSTAPATSSSTVTTAKTSAVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSISEKSDIDGATLEEAEESTPAQKRKGRQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFRLRDLSKLSTEQINSQIAQTKSPSEKMVTSSPEEDLGTSYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLYVSELEKQ
Protein: Mannan endo-1,6-alpha-mannosidase (EC 3.2.1.101) (Q6FJM7)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Mannan endo-1,6-alpha-mannosidase DCW1
- Autophagy-related protein 17
- Autophagy-related protein 31
- Autophagy-related protein 13
Sequence:
MKLLFSLQLWVLIGTLFPDAGAINLQDNKDSICAATALIQGGMLDYYEGTRYGGTVGMFQPPYYWWQAGVAFGGMLENWFLCQNDTYKDLLMNALVAQTGPNYDYIPANQTTVEGNDDQGVWGLTILDAVERNFSAPIDGKPGWLAMSQGIFNTMYARWDMQSCNGGLRWQIFTWNSGYNYKNTISNACLFQIAARLGRYTGNTTYLDVAERVFDWLVGVGYIVLSEKGNVYDGAKVEDNCTDITAIEWTYNHGVVLGGLAYMYNATNGSSVWQSRLTSVLGGATAYFFQDDIMYESACQPYKTCNNDQRCFKSIFSRMLGFTSVLAPFTSDTIDPLLKASAMAAAGSCDGGTDGHTCGLDWQLKTNDGYYGLGEQMSALEVIQQLLIHERPAPYRADNGGTSVGDAAAGLNSTTTNVLKNNLKITGGDRAGAAIVTTIVLGIIIGGAAWMMF
Protein: TipE homolog 1, isoform B (A0A0B4KGN9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- IP11896p
- RT03134p
Sequence:
MRSGSSELLLEQQQQELRLRKIRELAPKKKNGNRRFRSWRERARFYGTSTLAFFSVTAGASLLFLVPLYVDPAISTLSHDFIEKPTLCTTTRREDLVGIFNCSWSSCREGCTSDLYRCVHIYVTFIEQNITIPENMTDYSNFTSDMEQSGEATLLVNIKGCGYPPSVTCKNFNGYYGIEGAIFPCFYSRKNKTVVLTSYNHDDQVAMIIHFFAVPFVITVISSIALCIMHCDCRCKKDRSHRRNRPQCRRPRIENLSDTSISTRVDMLTPAIEVYKPPLXHKDDTVESNLGNPSTSSDF
Protein: Uncharacterized glycosyl hydrolase Rv2006 (EC 3.2.1.-) (P9WN15)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Trehalose synthase/amylase TreS
- Malto-oligosyltrehalose trehalohydrolase
- Trehalose-phosphate phosphatase
- Trehalose-6-phosphate synthase
- Trehalase
- Uncharacterized glycosyl hydrolase Rv3401
- Uncharacterized protein Rv2004c
- ATP-dependent 6-phosphofructokinase isozyme 2
- Uncharacterized protein Rv2003c
- Universal stress protein Rv2005c
Sequence:
MRCGIVVNVTGPPPTIDRRYHDAVIVGLDNVVDKATRVHAAAWTKFLDDYLTRRPQRTGEDHCPLTHDDYRRFLAGKPDGVADFLAARGIRLPPGSPTDLTDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVRVAAHTSHRNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETAKRLGANPGRCVVIDSCQTGLRAGRNGGFALVIAVDAHGDAENLLSSGADAVVADLAAVTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFDGTLSDIVERPEAATLVDGAAEALRALAAQCPVAVISGRDLADVRNRVKVDGLWLAGSHGFELVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIAGAVVEHKRFAVAVHYRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVELRPDIAWDKGKALDWIGERLGPAEVGPDLRLPIYIGDDLTDEDAFDAVRFTGVGIVVRHNEHGDRRSAATFRLECPYTVCQFLSQLACDLQEAVQHDDPWTLVFHGYDPGQERLREALCAVGNGYLGSRGCAPESAESEAHYPGTYVAGVYNQLTDHIEGCTVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELLSYRQTFDLRRATLTRSLRFRDAGGRVTTMTQERFASMNRPNLVALQTRIESENWSGTVDFRSLVDGGVHNTLVDRYRQLSSQHLTTAEIEVLADSVLLRTQTSQSGIAIAVAARSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQSVTLEKVATIFTSRDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLWERCAIDLTGNTEELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYRGHVFWDALFVAPVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMYPWQSGSDGSEVSQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVTGDRQYLVDCGAELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYPGNEYDGIDNNAYTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQERDQWDDVSRRMFVPFHDGVISQFEGYSELAELDWDHYRHRYGNIQRLDRILEAEGDSVNNYQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTVDYYLARTSDGSTLSAVVHAWVLARANRSNAMEYFRQVLRSDIADVQGGTTQEGIHLAAMAGSIDLLQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYRRHQLSLRISGRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR
Protein: Galactitol 2-dehydrogenase (GDH) (EC 1.1.1.16) (RlGDH) (Q1MLL4)
Organism: Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae)
Function: Catalyzes the oxidation of galactitol to D-tagatose. Also catalyzes the oxidation of a wide range of substrates, including polyvalent aliphatic alcohols and polyols, to the corresponding ketones and ketoses. Galactitol is the preferred substrate.
Interaction partners:
Sequence:
MSYQQKFRLDGERAVVTGGGRAIGLCCTEALAEAGAAVVVIERSEADAEQALALRNRGYDVEVRVGDVTDAARMDAIATELADGGRPATILVNNAGIGQSGIPAQDLTDADWLRMMDVNLNGVFWCSRAFGRSMISMKRGAIVNLGSMSGTICNRPQPQTAYNVSKAAVHHLTRSLAAEWAHHGIRVNAVAPTYIETPMVVAVEANRERIPLWLADTPMARMGTPEEVASAVLFLASGAASLMTGAIVNVDAGFTCW
Protein: Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1) (Q9H9Y2)
Organism: Homo sapiens (Human)
Function: May be required for ribosome biogenesis.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
Interaction partners:
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- Protein MAK16 homolog
- WD repeat-containing protein 74
- Probable rRNA-processing protein EBP2
- 60S ribosome subunit biogenesis protein NIP7 homolog
- Ribosome biogenesis protein BRX1 homolog
- mRNA turnover protein 4 homolog
- Ribosomal L1 domain-containing protein 1
- Nucleolar complex protein 2 homolog
- Pescadillo homolog
Sequence:
MAKAGDKSSSSGKKSLKRKAAAEELQEAAGAGDGATENGVQPPKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL
Protein: Dipeptide ABC transporter, periplasmic dipeptide-binding protein (Q5LP03)
Organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Interaction partners:
- Dipeptide ABC transporter, permease protein
- Dipeptide ABC transporter, permease protein
- Oligopeptide ABC transporter, ATP-binding protein
- Oligopeptide/dipeptide ABC transporter, permease protein
- Oligopeptide/dipeptide ABC transporter, permease protein
- Oligopeptide/dipeptide ABC transporter, ATP-binding protein
Sequence:
MSFNKRTDELAGGSLPGHVLAAADHARSGSAMDRREFLALASVFGATAATAYGMLGMAAPAQAATPRRGGTLRLEVGVHALKDTRTMDFAAMSMVASNWLEYLVEYNNDGTFKPRLLDSWEVNADATEYTLKVRKGVTWNNGDAFTAQDVARNIERWCDAEVEGNSMASRMNSLVDPETKKAAAGAITVVDDETVKLTCRSSDITIIPGLADYPALVVHESYTPETMLTNPVGTGPYKPVEFEVGVRAAVERNTEHAWWGEGTGAWLDRIEFLDYGTDASAVLSAVEADEIDVTYNTSGEYLELIEALGWHTSEIATGSTVVIRANQQAEVNGQKPYADVRVRKALQMAVDNNVVLELAFNNNGKVAQNHHVAPVHPEYADIGDPVHDPAGARALIEEAGMADFEHELISIDGGFRKDTADVVAIQLRDAGIKVKRTIMPGSTFWNDWTKYPFSITDWNHRPLGVQLYGICYRSGQKWNEAGFANAEFDALLDQAVAVADPAKRSEITAKMEQIMIDEAVIIQPYWRSLFRQSREGVLNAEPHISFLPQLYKWGWA
Protein: Probable serine/threonine-protein kinase PBL11 (EC 2.7.11.1) (PBS1-like protein 11) (P43293)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in the regulation of plant growth and development (Probable). May be involved in plant defense signaling (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O48814}; Lipid-anchor {ECO:0000250|UniProtKB:O48814}.
Interaction partners:
- Nudix hydrolase 23, chloroplastic
- Pectate lyase
- Protein RIK
- Probable ubiquitin-like-specific protease 2B
Sequence:
MGGCFSNRIKTDIASSTWLSSKFLSRDGSKGSSTASFSYMPRTEGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKASNILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEELHIQKEASKEQQNPQISIDNIINKSPQAVNYPRPSIM