wanglab/gogpt-training-data huggingface dataset:
Protein: Tricalbin-2 (P48231)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May play a role in membrane trafficking.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15141306}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22250200}; Multi-pass membrane protein {ECO:0000255}. Note=Traffics from the cell surface to intracellular vesicles near the vacuole (PubMed:15141306). More enriched in the cortical endoplasmic reticulum (ER) that is closely apposed to the cell membrane than in the perinuclear ER or internal ER tubules that connect the nucleus to the cortical ER (PubMed:22250200). {ECO:0000269|PubMed:15141306, ECO:0000269|PubMed:22250200}.
Interaction partners:
- Vesicle-associated membrane protein-associated protein SCS22
- Increased sodium tolerance protein 2
- Vesicle-associated membrane protein-associated protein SCS2
- Exocyst complex component SEC3
- Exocyst complex component EXO84
- Putative uncharacterized protein YNL089C
- Exocyst complex component SEC5
- Nucleus-vacuole junction protein 2
Sequence:
MSPNSSKTRTDQISSMPGINEATKVESKNVVKDAVPIKSEVETNGTSIVREKQDPSYVGWKQVGGWEEKDELTSEDLLVDVNKDTFLGNLLPDKFYGDWYHEVAILIIAGLCSFVLGYFKFSLASVLIVMLTTGMLYRTSSKKYRESLRDLAQKEQTVEKITSDYESVEWLNTFLDKYWPIIEPSVSQQIVDGTNTALSENVAIPKFIKAIWLDQFTLGVKPPRIDAIKTFQNTKSDVVVMDVCLSFTPHDMSDLDAKQCRNYVNSNVVLKAKIFGMDIPVSVADIFFQVFVRFRFQLMTTLPLVETINIQLLEVPEVDFISRLLGNSVFNWEILAIPGLMRLIQKMAFKYLSPVLLPPFSLQLNIPQLLSKTGLPIGVLEIKVKNAHGLRKLVGMIKKTVDPYLTFELSGKIVGKTKVFKNSANPVWNESIYILLQSFTDPLTIAVYDKRETLSDKKMGTVIFNLNKLHANHYHKNEKVHFLRNSKPVGELTFDLRFFPTIEPKKLLNGDEEPLPDMNTGITKITIRELKGLDELSDKKFVFAELYVNAELVMTTKKEKRTAHLKWNSDYYSVVTDRRKTICRFVLKDQSGKVISSSVQPLNHLIDRTEVNKEWIPLRNGKGELKVTTYWRPVDIDLGLKSVGYTTPIGMLRVFINKAENLRNPDSLGKISPYAKVSVNGVARGRTNERIETLNPIWNQSIYVSVTSPLQKVSIDCFGIDTNGDDHNLGSLNIQTQNIYHKDNDDKYTIFIDNAPRTGNLIGKKGVKGTVTYYLSFYPVVPVLSLEEAKEVDEINEKKDKLEKQKSTLDDKNISKEEKERIKKEEFRLTEKYDMYSYKMKLDLDELLQYNAGVLGVTVLGGELPQPGLYVQTFFDSCGYAAITSAKNAIRTIKTGWSGDFMIKELEWSVTTFRVTKTKDANKAENFICEVNIPTIELVRNCYYKPSVLNLIGKKSAKLLVQVSWFPVTATELPQSDLITNSGDLKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQKKTLNPTWNESKTIEVSNRVNDYLTINVKDYESTNSNRSIGKAVVPLSTIDPESDTTFNIPLVGPKGEDGGVLHLEFEFEPRYTTNVVKREAGLGNFATKGLGTGIKAGSTVFALGTNVVSTGLGTIDKVKAGVFGGKKSTTTGDKKSEEKQ
Protein: Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) (Q61062)
Organism: Mus musculus (Mouse)
Function: Involved in the signal transduction pathway mediated by multiple Wnt genes.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O14641}.
Interaction partners:
- Vang-like protein 2
- Axin-1
- Vang-like protein 1
- Protein naked cuticle homolog 1
- Axin-2
- Segment polarity protein dishevelled homolog DVL-2
- Prickle-like protein 1
- Segment polarity protein dishevelled homolog DVL-1
- Protein naked cuticle homolog 2
- Prickle-like protein 2
Sequence:
MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPPSMERTGGIGDSRPPSFHPHASGGSQENLDNDTETDSLVSAQRERPRRRDGPEHAARLNGTTKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLTSSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM
Protein: Non-specific lipid transfer protein GPI-anchored 11 (AtLTPG-11) (Protein LTP-GPI-ANCHORED 11) (Xylogen protein 2) (AtXYP2) (Q9ZQI8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable lipid transfer protein (By similarity). Proteoglycan-like factor that exhibits xylogen activity consisting in mediating local and inductive cell-cell interactions required for xylem differentiation.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000255}; Lipid-anchor, GPI-anchor {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
Interaction partners:
- Carbohydrate-binding X8 domain superfamily protein
- Carbohydrate-binding X8 domain superfamily protein
- At2g03505
- Carbohydrate-binding X8 domain superfamily protein
- SKU5 similar 3
- Uncharacterized protein
- Non-specific lipid-transfer protein 5
- Non-specific lipid-transfer protein 6
- Cysteine-rich receptor-like protein kinase 10
- LOB domain-containing protein 15
Sequence:
MAYATILMIFSVVALMSGERAHAAVDCSSLILNMADCLSFVTSGSTVVKPEGTCCSGLKTVVRTGPECLCEAFKNSGSLGLTLDLSKAASLPSVCKVAAPPSARCGLSVSGDPPATAPGLSPTAGAGAPALSSGANAATPVSSPRSSDASLLSVSFAFVIFMALISSFY
Protein: Cyclin-dependent protein kinase inhibitor SMR3 (Protein SIAMESE-RELATED 3) (Q9LZ60)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle.
Subcellular location: Nucleus {ECO:0000269|PubMed:17098811}.
Interaction partners:
- Cyclin-dependent protein kinase inhibitor SMR8
- Cyclin-dependent protein kinase inhibitor SMR2
- Cyclin-dependent protein kinase inhibitor SMR6
- Cyclin-dependent protein kinase inhibitor SMR16
- Cyclin-dependent protein kinase inhibitor SMR5
- Cyclin-dependent protein kinase inhibitor SMR1
- Cyclin-dependent protein kinase inhibitor SMR11
- Cyclin-dependent kinase A-1
Sequence:
MAEICCVKEIQEEDVEKIRLPTRPELDIPDSDHEDPTVNEEEGCKTPTSSDHKIPEVKYTLCPPAPRKPKPNRSSGTKRKLTPVNVVNRIPIDLSREIEMFFEDLDRRIKKSRKQ
Protein: Protein C-ets-2 (P15036)
Organism: Homo sapiens (Human)
Function: Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.
Subcellular location: Nucleus.
Interaction partners:
- Cellular tumor antigen p53
- Protein C-ets-1
- DNA-binding protein inhibitor ID-1
- Cyclin-dependent kinase 10
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 3
- Protein c-Fos
- Serum response factor
- CREB-binding protein
- ETS domain-containing transcription factor ERF
Sequence:
MNDFGIKNMDQVAPVANSYRGTLKRQPAFDTFDGSLFAVFPSLNEEQTLQEVPTGLDSISHDSANCELPLLTPCSKAVMSQALKATFSGFKKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLQRFGMNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEENSHLTSVPHWINSNTLGFGTEQAPYGMQTQNYPKGGLLDSMCPASTPSVLSSEQEFQMFPKSRLSSVSVTYCSVSQDFPGSNLNLLTNNSGTPKDHDSPENGADSFESSDSLLQSWNSQSSLLDVQRVPSFESFEDDCSQSLCLNKPTMSFKDYIQERSDPVEQGKPVIPAAVLAGFTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED
Protein: Transmembrane channel-like protein 1 (F1QFU0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Probable ion channel required for the normal function of hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machinery.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8R4P5}; Multi-pass membrane protein {ECO:0000255|RuleBase:RU310713}. Note=Localized to the hair bundles of the hair cells. {ECO:0000269|PubMed:28534737}.
Interaction partners:
- Calcium and integrin-binding family member 2
- Protocadherin-15
- LHFPL tetraspan subfamily member 5b
- Protocadherin-related 15b.
- Myosin VIIAa
- Transmembrane inner ear.
- Cadherin-related 23.
- Harmonin
- Myosin VIIAb
- Otoferlin
Sequence:
MPRHKLIASESDVSIEVDEGKDKESCVYYVEVEENCERGKIKQASRDGKRRRERNGETRRKASEKRTNEGESKKAEKKHEKGHRTARKAGEKHGKRQRRKNAGEEDAEDKSSKEKKNMKNEKNKTLKLEEEKEKDVRKKKRKHVKNEEDETNHEKTKQHLKEEKRRKKRKKPETTSESESKSESESASESESKNSPAVGVLGSLTPEELENLKEAVEERKKLITQLKGKPWPMRRKLVVLRESQEFVEKYEGALGKGKGRKLYAYKVMMMKKWMKFQRDFENFKTACIPWEMKIKEIESHFGSSVASYFIFLRWMYGINMILFGLTFGLVMVPEALMGKPYGSLPRKTVPREEEASAMNFAVLWDFGGYAKYSVLFYGYYNSQRAIGWLKFRMPLSYFLVGVGTVAYSYMVVIRTMARNANEEGGGDDTSFNFSWKTFTSWDYLIGNPETADNKFASITTSFKEAIVEEQESRKDDNIHLTRFLRVLANFLVLCCLAGSGYLIYFVVRRSQKFALEGLENYGWWERNEVNMVMSLLGMFCPMLFDVISTLENYHPRIALQWQLGRIFALFLGNLYTFIIALMDAIQLKRAEEEIVKKNMTIWQANLYNGTVPDNSTAPPLTVHPADVPRGPCWETMVGQEFVRLIISDTMTTYITLLIGDFMRAVLVRFLNNCWCWDLEYGFPSYSEFDVSGNVLGLIFNQGMIWMGAFYAPCLPALNLLRLHVSMYLQCWAVMCCNVPQERVFKASGSNNFYMAMLLVILFLSTLPAIYTIVSIPPSFDCGPFSGKPRMFDVIQETLETDFPAWFSKVFSYASNPGLVLPFLLLLVLAIYYLQSTSKTYKRVNMELKKKLQAQNEENKKKNKLAALKAASDLEQARKAGEQRRNSISDLGVNEENPESHVSSSHTSRPPASRGHTSSGHLPGHPQQPQKNSKKR
Protein: Gca2p (A0A1D8PEW1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Glucoamylase 1
- Glucan 1,3-beta-glucosidase BGL2
- glucan 1,4-alpha-glucosidase
- Glucan 1,3-beta-glucosidase
- Alpha-glucosidase
- beta-glucosidase
- beta-glucosidase
- Glycosyl hydrolase family 13 catalytic domain-containing protein
- Hexokinase-2
- Phosphotransferase
Sequence:
MKLLSKVFVTALGLSSIASAAPTSSSSAENAQKTVPTELTLGVKQVPNILNDTAVDANVAAKGYSLVNVTLTGRGLTGILKLKEATNIYGYDFEYLNLSVEYQSDTRLNVHIEPTDLTDVFVLPEELVVKPKLEGDAKTFNFENSDLVFEYDEEDFGFEVLRSSTREVLFSTKGNPLVFSNQFIQFNTTLPKGHSITGLGESIHGSLNEPGVVKTLFANDVGDPIDGNIYGVHPVYYDQRYNTNTTHAVYWRTSAIQEVVVGETSLTWRALSGVIDLYFFSGPDPKDVIQQYVSEIGLPAMQPYWALGYHQCRWGYDTVESLETVVENFKKFDIPLETIWSDIDYMDGYKDFTNDPYRFPTDKFRKFLDDLHNNSQHYVPIFDAAIYVPNPNNATDNDYEPFHLGNESDVFLKNPDGSLYIGAVWPGYTVFPDFLANNTQEYWNKMFKDWYERIPFDGIWTDMNEVSSFCVGSCGTXRYFDNPVHPPFEVGYSGSDYPLGFDKSNASEWKSISEAAAATKTTTTTSSSTSTSIDGKNTLAPGKGNINYPPYAINNDQGDHDLATHAISPNATHADGTVEYDIHNIYGLIQERAIYEALLEIHPNKRPFIIGRSSFAGSGKYMGHWGGDNYADYYMMYFSIPQALSMGLSGIPFFGVDACGFNGNTDMELCSRWMQLASFFPFYRNHNVLGAIPQEPYVWEGVMKATKTSINVRYSLLPYYYTLLHESHVTGIPIMRAFNWQFPYSKELAGVDTQFFVGDALLVTPVLEPGVNHTKGVFPGENAVYYDFYTHKKQKFTAGKNETLAAPLGHIPLHIKGGNIIPTQEPGYTTTESRKNPFGLLVALDAEGTASGKLYLDDGESVDVEEALYVDFVASKNKLVASVFGEYEVRQPLANVTILGVDSEPKKVLFNNETVSHKYENGAVYLTDLEKFTKEGAFAEEFTLQW
Protein: CST complex subunit TEN1 (Protein telomeric pathways with STN1 homolog) (Telomere length regulation protein TEN1 homolog) (Q9D7K2)
Organism: Mus musculus (Mouse)
Function: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. The CST complex inhibits telomerase and is involved in telomere length homeostasis; it is proposed to bind to newly telomerase-synthesized 3' overhangs and to terminate telomerase action implicating the association with the ACD:POT1 complex thus interfering with its telomerase stimulation activity. The CST complex is also proposed to be involved in fill-in synthesis of the telomeric C-strand probably implicating recruitment and activation of DNA polymerase alpha. The CST complex facilitates recovery from many forms of exogenous DNA damage; seems to be involved in the re-initiation of DNA replication at repaired forks and/or dormant origins (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:19854130}. Chromosome, telomere {ECO:0000269|PubMed:19854130}.
Interaction partners:
- CST complex subunit STN1
- CST complex subunit CTC1
- Protection of telomeres protein 1
- Protection of telomeres protein 1
- DNA polymerase alpha subunit B
- DNA primase small subunit
- DNA primase large subunit
- DNA polymerase alpha catalytic subunit
- Adrenocortical dysplasia protein
- TERF1-interacting nuclear factor 2
Sequence:
MLPKPGVYYFPWEVSDGHVPEGSTLRTFGRLYLYDMARSLMTLAAPQKPDQCQLLVCTNLVEPFEAHVNFLYMVLGDLERMEGGAFVVRARLLTCVEGMDLSLLEKAILEQRRHLQKRQQPIGDASTLQTPTPAPQSIPSDSLSLEPENRGQQVPLPQTLD
Protein: Coiled-coil domain-containing protein 40 (Protein links) (Q8BI79)
Organism: Mus musculus (Mouse)
Function: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21131972}. Cell projection, cilium {ECO:0000269|PubMed:21131972}. Note=Localizes to cytoplasm and motile cilium. {ECO:0000269|PubMed:21131972}.
Interaction partners:
Sequence:
MMDAEKVSTDGEAISEGEVGSNGETPPETEVEFIGETAPDTDVEFIGETSPGTDVEPTGESIQETEVESIGEATPGMDVEPIKKTMTELNVESIGEETSETDVDSIRKALRGIDLESITVAYPPKKAKHRKVRPQAEVESTGRAAPEGELEVSDHEKVEALLDELDELSEIVSSPEVSYSDISPLEMGEDDTNVSATSTDTFQQGIYEPIEPIEPTEPPEPAEPPKPAETPEDSTVRAPAHPYQRDFPMGARHRFRLSIMGSLTPSDTDDLPLETDEPPQQESVQSTPRALEETRIQFLDQVQSLSPEALLDRATEGSDEAEEEGSQLIVLDPDHPLMIRFQEALKGYLNRQMDKLKLDVQELDVATKQTRSQRQELGVNLYGVQQHLARLQMQLEKSHDRHSLVACERRRKEEELQCARSVYNKTCQTANEERKKLAALQTEVESLALHLFYMQNIEQDVRDDIQVMKQVVRKTETEKMHAEVEKKKQDLFVDQLTERSHQLEENIALFEAQYLSQAEDTRVLKKAVTEAITEIDTIAVEKKRILQQWTTSLVGMKHRNEAYKTVMDALRECQHQVKSTDSEIEVCKKSIMQEEEKNEKLARLLNRAETEATLVQKMTAQCLSKQEALQTEFNTYQLALQDTEEMLNKGYVEHSAVLSELQATRQAFHQEQELRQKMDMSMVDKLQEQGTSSKMTKYFHQLLRKLQKENTNLVTHLSKIDGDIAQATLDITNTNCKIDMHKKTLAEMDKEVKRFNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSELGGEEAGPLELEIKRLSKLTEEYNTGVAEAQMTWLRLQQELVQVTHEREEQLVSVDQLKKEVHIMEQKKLRIESKIAHEKKEQKIVSRHMRDLDNDLSKLNMLLDKNRCSSEELEQNNIATETEFLRTLKDSERETIQMQEKLMELSEEKATLLNSFMEAEHQIMLWEKKIQLAKEMRSSVDSETGQTEIRAMKAEIHRMKVRHGQLLKQQEKMIRDMELAVARRETIVVQAEGQSKIDKKVITKTEFHYQQRELQKKVREMHKATDDCTNTISELEETQKFLSSSLQEKQQLLSEMQATTDVLEEEINQLTALKRQNLLEIVTLQTRGKHLQAAIEGKYVFLHRNSRSQLMERKRLSVRLSQLNKVLSSVQEDYPQYQEVLQSIQQKIATKLETPEPS
Protein: Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Stretch-activated channel 2B) (Vanilloid receptor-like protein 1) (VRL-1) (Q9WUD2)
Organism: Rattus norvegicus (Rat)
Function: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:14622291, ECO:0000269|PubMed:14991772, ECO:0000269|PubMed:15249591}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:Q9WTR1}. Melanosome {ECO:0000250|UniProtKB:Q9Y5S1}. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation. {ECO:0000250|UniProtKB:Q9WTR1}.
Interaction partners:
- Transient receptor potential cation channel subfamily M member 7
- Transient receptor potential cation channel subfamily M member 2
- Transient receptor potential cation channel subfamily M member 8
- Insulin-like growth factor 1
- Transient receptor potential cation channel subfamily A member 1
- Transient receptor potential cation channel subfamily M member 4
- Transient receptor potential cation channel subfamily M member 3
- Short transient receptor potential channel 1
- G protein-coupled receptor 55
- Ankyrin 1
Sequence:
MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP
Protein: At2g35070/T4C15.26 (Expressed protein) (Transmembrane protein) (O82184)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MAMLKRTISIVRIGRGLSYRSLSSGNHVDKLGMVKALEAINVPSTQAEALTGAITSGFESVMGKVKADIAKSEEYKSTRVAEEFRKMRADIEKMRADIATIQAEERCDHDNHIHKVEQGFNELKDEFDATKYKIVKYAIYTLIPVAAAETGMLFSMIY
Protein: Miranda (O45116)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSFSKAKLKRFNDVDVAICGSPAASNSSAGSAGSATPTASSAAAAPPTVQPERKEQIEKFFKDAVRFASSSKEAKEFAIPKEDKKSKGLRLFRTPSLPQRLRFRPTPSHTDTATGSGSGASTAASTPLHSAATTPVKEAKSASRLKGKEALQYEIRHKNELIESQLSQLDVLRRHVDQLKEAEAKLREEHELATSKTDRLIEALTSENLSHKALNEQMGQEHADLLERLAAMEQQLQQQHDEHERQVEALVAESEALRLANELLQTANEDRQKVEEQLQAQLSALQADVAQAREHCSLEQAKTAENIELVENLQKTNASLLADVVQLKQQIEQDALSYGQEAKSCQAELECLKVERNTLKNDLANKCTLIRSLQDELLDKNCEIDAHCDTIRQLCREQARHTEQQQAVAKVQQQVESDLESAVEREKSYWRAELDKRQKLAENELIKIELEKQDVMVLLETTNDMLRMPDEKLQKCEEQLRNGIDYYIQLSDALQQQLVQLKQDMAKTITEKYNYQLTLTNTRATVNILMERLKKSDADVEQYRAELESVQLAKGALEQSYLVLQADAEQLRQQLTESQDALNALRSSSQTLQSEVSLKESLLHELLAGEAETLAKFNQIANSFQERIDGDAQLAHYHELRRKDETREAYMVDMKKALDEFATVLQFAQLELDNKEQMLVKVREECEQLKLENIALKSKQPGSASLLGTPGKANRSNTTDLEKIEDLLCDSELRSDCEKITTWLLNSSDKCVRQDTTSEINELLSAGKSSPRPAPRTPKAAPHTPRSPRTPHTPRTPRSAASTPKKTVLFAGKENVPSPPQKQVLKARNI
Protein: Probable WRKY transcription factor 46 (WRKY DNA-binding protein 46) (Q9SKD9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor involved in the regulation of osmotic stress responses and stomatal movement. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora. Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2. Together with WRKY54 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223}.
Interaction partners:
- Probable WRKY transcription factor 51
- Aluminum-activated malate transporter 1
- 4-substituted benzoates-glutamate ligase GH3.12
- Protein SAR DEFICIENT 1
- Probable WRKY transcription factor 33
- High mobility group B protein 6
- Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
- Isochorismate synthase 1, chloroplastic
- F22C12.10
- Protein EDS1
Sequence:
MMMEEKLVINELELGKELANRLMNNLKHTSSVDSNKTLISDILRIYQNAIFMLSFNQDKNILKRSLEIDGKDSKNVFKKRKVSEKNTEKVKVFVATEQENGSIDDGHCWRKYGQKEIHGSKNPRAYYRCTHRFTQDCLAVKQVQKSDTDPSLFEVKYLGNHTCNNITSPKTTTNFSVSLTNTNIFEGNRVHVTEQSEDMKPTKSEEVMISLEDLENKKNIFRTFSFSNHEIENGVWKSNLFLGNFVEDLSPATSGSAITSEVLSAPAAVENSETADSYFSSLDNIIDFGQDWLWS
Protein: DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (A0A1B0GTU7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
XLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLEKRSQPGP
Protein: Gamma-crystallin E (Gamma-E-crystallin) (Q03740)
Organism: Mus musculus (Mouse)
Function: Crystallins are the dominant structural components of the vertebrate eye lens.
Interaction partners:
- Gamma-crystallin D
- Gamma-crystallin C
Sequence:
MGKITFYEDRGFQGRHYECSTDHSNLQPYFSRCNSVRVDSGCWMLYEQPNFAGCQYFLRRGDYPDYQQWMGFSDSVRSCRLIPHSSSHRIKIYEREDYRGQMVEITDDCSHLQDRFHFSDFHSFHVMEGYWVLYEMPNYRGRQYLLRPGEYRRYHDWGAMNARVGSLRRIMDFY
Protein: RNA uridylyltransferase (EC 2.7.7.52) (Q4Q9F2)
Organism: Leishmania major
Interaction partners:
- MP81
- RNA ligase
- MP18
- RNA uridylyltransferase
- MP63
- RNA helicase
- RNA-editing ligase 1, mitochondrial
Sequence:
MHAPTPLYLYVAVTRGLCSSAVAASSSADAASSPSAASSSTSEGVSYASHLVASNDHYVQWGRALLEENSKRIGPEQMFRTAIRAQQQLQMLADKWTPDAKIYCCGSLVTHGQMEWGSDLDLACVFDDPYPDHSVQAKRTEKLWSVVKRYMPQFLRNNLLALTEARTPVVKLRYVNDDKVARGRYTVLTEEEDRKSRTTLWDIRNRHLDSKDLEYIATKMGRENIEGIWVERTTYGCRCAVQCTSREQAVEAVGFFPDGVIMTKGMREDYTRDMLDLRYVPEMFMYKWDISFVAYGVKNSYLLRHYLHNGPPAARHAAMAAKAWGKASGVGLGTAAMLTSYAVTVMFVHYLLATRQLAWIDPWSLAHPVHMPRFPDFSPLLDCDPAELGKLLHGFFIYYASHFNYEKNIISLSRPRLSLRSDVNWNFPQSKQGTFSYLLGIEDPYEDVGVGGLNLGRHLHPAKFNQVKQEFARAATTMERYVPSNAPEKTILGVRRGGTSNHHHHHNRFD
Protein: Neurogenin-2 (NGN-2) (Helix-loop-helix protein mATH-4A) (mATH4A) (Protein atonal homolog 4) (P70447)
Organism: Mus musculus (Mouse)
Function: Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Achaete-scute homolog 1
- Paired box protein Pax-6
- Oligodendrocyte transcription factor 2
- LIM/homeobox protein Lhx3
- Insulin gene enhancer protein ISL-1
- LIM homeobox transcription factor 1-alpha
- POU domain, class 3, transcription factor 2
- Transcription factor E2-alpha
- Myelin transcription factor 1-like protein
- Homeobox protein DLX-2
Sequence:
MFVKSETLELKEEEEVLMLLGSASPASATLTPMSSSADEEEDEELRRPGSARGQRGAEAEQGVQGSPASGAGGCRPGRLLGLMHECKRRPSRSRAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCAGAGGLQGALFTEAVLLSPGAALGASGDSPSPPSSWSCTNSPASSSNSTSPYSCTLSPASPGSDVDYWQPPPPEKHRYAPHLPLARDCI
Protein: Intron-associated endonuclease 1 (EC 3.1.-.-) (I-TevI) (IRF protein) (P13299)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing.
Interaction partners:
Sequence:
MKSGIYQIKNTLNNKVYVGSAKDFEKRWKRHFKDLEKGCHSSIKLQRSFNKHGNVFECSILEEIPYEKDLIIERENFWIKELNSKINGYNIADATFGDTCSTHPLKEEIIKKRSETVKAKMLKLGPDGRKALYSKPGSKNGRWNPETHKFCKCGVRIQTSAYTCSKCRNRSGENNSFFNHKHSDITKSKISEKMKGKKPSNIKKISCDGVIFDCAADAARHFKISSGLVTYRVKSDKWNWFYINA
Protein: CTP synthase (EC 6.3.4.2) (UTP--ammonia ligase) (F4I6G9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alkaline-phosphatase-like family protein
- GMP synthase
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase 1
- Nucleoside diphosphate kinase II, chloroplastic
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- Delta-1-pyrroline-5-carboxylate synthase B
- Aspartate--tRNA ligase, chloroplastic/mitochondrial
- Protein trichome birefringence-like 21
- UMP kinase
Sequence:
MKYVLVTGGVVSGLGKGVTASSIGVLLKACGLRVTSIKIDPYLNTDAGTMSPFEHGEVFVLDDGGEVDLDLGNYERFLDIKLTRDNNITTGKIYQHVIAKERKGDYLGKTVQVVPHVTDAIQDWIERVAVIPVDGEEDPADVCVIELGGTIGDIESAPFIEALGQFSYRVGPGNFCLVHVSLVPVLNVVGEQKTKPTQHSVKGLRGLGLTPDILACRSTKPLEDNVKEKLAQFCHVPLEYIFTLYDVPNIWRIPLLLKDQKAHLAISKVLNLASILNEPSLGEWTSRAELCDNLHVPVRIAVVGKYTGLSDAYLSVLKALLHASVACRKKLVVDWVPACDLEKETEKENPDAYKAAWKLLKGVDGILVPGGFGDRGVEGKILAAKYARENKIPFLGICLGMQIAVIEFARSVLSLQDANSTEFNPETKHPCIIFMPEGSKTHMGGTMRLGSRKSIFNVKDSKSAKLYENKSFVDERHRHRYEVNPDMVERLEKAGLSFAAKDETGKRMEIIELPNHPFFIGAQFHPEFKSRPGKASPLFLGLIAASCGELDTVLNPASAHQHSISNGPTNIFINGTSKKSPNGLADVRYNNGYCNGLYTR