Protein: Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) (Q9V5N8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the fz signaling pathway that controls wing tissue polarity. Also mediates homophilic cell adhesion. May play a role in initiating prehair morphogenesis. May play a critical role in tissue polarity and in formation of normal dendrite fields. During planar cell polarity, stabilizes asymmetric PCP domains together with ATP6AP2.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10490098}; Multi-pass membrane protein {ECO:0000269|PubMed:10490098}. Apical cell membrane {ECO:0000269|PubMed:23292348}. Note=Co-localizes at the apical junctions with ATP6AP2. {ECO:0000269|PubMed:23292348}.
Interaction partners:
- Vang-like protein
- Frizzled
- Diego, isoform A
- Protein prickle
- Protein espinas
- Segment polarity protein dishevelled
- Frizzled-3
- Protein inturned
- Golden goal
- Anastral spindle 2, isoform A
Sequence:
MQTREFPQRPLGLLLVLLVVLLQSSLIKSYLIIVHEDTPPGTVIFNASVYKLGSERHYKINAHKSANFVHHLVSVNHKDGQIQLRKALKCDGIYYPNLFTFYVDSTSNRLRSIDYYSLPVRIFVSGHSCNEDRRIEQELHHHHYEEEDNTGYSKRRRRRSTQEMIQLNGNQLEEVFRQNSTEFRAGDLIFGDSFDNEMRHRILSRKRRAVGSPDPLHLQPALHRRISDAKQWISETYASYAIHTTDKWNQICLRRSQFINSLNAFLPRSVCQHCKVSFLDVNDERFAIEHQSRDLVASRDVCIAESMWKVSITFNIRCDRRDIVDSDHRLKIVYHHQEFNDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAFLSPLLNFFLDGLAAIIPCPKEHIFVFSIQDDTDVSSRILNVSFSARRPDVSHEEFYTPQYLQERVYLNRAILARLATVEVLPFDDNLCVREPCLNFEECLTVLKFGNASEFIHSDTVLFRPIYPVNTFACSCPEGFTGSKEHYLCDTEVDLCYSDPCQNGGTCVRREGGYTCVCPSTHTGQNCETGVGHLRPCPSETCEGGLSCLSNYPSSQPPPYTATCELRARAFGRNSFLTFESLKQRHRFNLKLRFATVQENGLLLYNGRYNELHDFIALEIHEGHVSFSFSLGDHSERISVIQEAKVSDGKWHQVEVVYLNRSVTLVLDNCDTAIALSGQLGDRWSCANRTTLKLDKRCSLLTETCHRFLDLTGPLQVGGLPRIPAHFPVTNRDFVGCISDLRIDDRFVDLNSYVADNGTLAGCPQKAPLCQSEPCFNGGTCREGWGTYSCECPEGYAGNSCQDNIPAPWRFSGDGSLSFNPLLRPIQLPWTTSFSLRTRQKEAFLLQIQIGQNSSAAVCLRQGVLYYIFDGEPMYLAGAFLSDGEWHRVEIRWQQGSEIHFSVDYGQRSGSVPMSQKVQGLYVGKIVMGSPDGSIGAVPEASPFEGCIQDVRIGAGQSVLSRPTIRENVEDGCESRAQCPDHCPNHSSCQSSWDLSTCECDSGYVGTDCAPICTVRPCASGVCRANTSLPRGYDCECNSSSRHGDYCEKELQQPCPGGWWGERVCGPCRCDLAQGYHPDCNKTTGQCYCKTNHYQPPNETACLSCDCYSIGSFSGACNPLTGQCECREGVIGRRCDSCSNPYAEVTLSGCEVVYDACPRSFAGGVWWPRTPLGGVAIEGCPPPARGKGQRSCDVQSGSWNTPDMYNCTSEPFVELRRQLSQLEKLELELNSFVAIKMAEQLRKACEAVDRRGASKDQKISGNGRPNRRYKMESSFLLSNGGNVWSHELEMDYLSDELKFTHDRLYGADLLVTEGLLQELINYELMQSGLNLSHSQDKYFIKNLVDAASVILDRKYEAEWRRATELIQRGPDDLVDAFNKYLVVLARSQHDTYTSPFEIVQPNMALGLDIVTTESLFGYEPEQLSEYHRSKYLKPNAFTTESVVLPDTSGFLQHSARQRPVISFPKYNNYILDRRKFDQHTKVLVPLEMLGITPPESDEISQSGRRGSSHDHRAIVAYAQYKDVGQLLPDLYDETITRRWGVDVELATPILSLQILVPSMEREQETQRLEIPSRKIFSSSSPSSSSSSGSTEQQFVEVFDVPKAPTSSSEQQIEDIRITAHEIPPPVSSVEQQEASSDEDGEEREPHIRLNLDDIEFHGNSGEEVISPDSPEMLNPNYEGVSSTGSDEQPKGENEAVYRDRRLVKRQVEITYPSEQMQQTEQVVYRSLGSPHLAQPIKLQMWLDVDSARFGPRSNPQCVRWNSFTNQWTRLGCQTEIPDFDGDFNPAAQQAILVNCSCTHISSYAVIVDVIDPEDIPEPSLLVQITSYSAFLVSLPLLLGVLLALALLRGQQTNSNTIHQNIVLCVFCAELLFFVGMQSRRQLLESEFPCKLTAICLHYFWLAAFAWTTVDCVHLYRMLTEMRDINHGPMGFYFAMGYGAPAIVVGLSVGVRAHEYGNSLFCWLSVYEPVVWWLVGPIAGMSVVNLLILFVSVKAAFTLKDHVLGFGNLRTLLWLSVVSLPLMGVMWVLAVLAASEHSQLLSLLLSGVVLLHALFCLIGYCIINKRVRENLQRTCLRCMGRKVPLLDSSMVVSNSSHNVNAAARPSNFLASGYDTTTRRNIGISASSTTSRSTAKTSSSPYSDGQLRQTSTSTSNYNSASDAPSFLRGFESSTTGRSRGGEEKPSRRQRKDSDSGSETDGRSLELASSHSSDDDESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELNVVQSPQLFPSVNKPVYAPRWSSQLPDAYLQSPPNIGRWSQDTGSDNEHVHGQAKMTISPNPLPNPDLTDTSYLQQHHNKINMPPSILENIRDAREGYEDSLYGRRGEYPDKYGSYKPPSHYGSEKDYPGGGSGSQTIGHMRSFHPDAAYLSDNIYDKQRTLGSGYLGAKSESPYLSKDRITPDIYGSRDGHYSLKRQPAYATDSLHSVHSLLKNDYHQQQQQQQQHHLQDRLSEGSDKNGYHFPYTAEEDHLPARKLSHTQPPSLHGSQLMQPPGVGLVNDVNNPGLMGRHTLNGGSRHSSRASSPPSTMVAPMQPLGPLTSITDTERNIDDDETTV