wanglab/gogpt-training-data huggingface dataset:
Protein: Novopsin-6 (Opsin 7, group member d) (E9QFB2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGNTSETTHFVSKIRKEHDVFMGSLYSIFCILSLLGNGVLLLVAYRKRSSLKPAEFFIVNLSFSDLGMTVSLFPLAIPSAFAHKWLFGELTCLCYAVCGVLFGLSSLTNLTALSSVCCLKVCFPNYGNKFSYSHACLMIVGVWCYAMVFAVGPLANWGHYGPEPYGTACCIDWYAPGQDALSMSYIICLFLLCYALPLGIILLSYILILITVRGSRQAVQQHVSPQTKTTNAHILIVKLSVAVCIGFLTAWSPYAVVAMWAAFGEPDNVPPMAFALAAIFAKSSTIYNPVVYLVFKPNFRKSLSRDTAQIRRRICSSPCKGSPVPGEKDLQRQTSLRCNKDASNSTRLSNGLADSHGACLHCTETDPHCQQTPTQRTACVLVGTSYSEVTVSQLPEKMQADFL
Protein: Dodecenoyl-CoA isomerase (Q5A318)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
Interaction partners:
- 3,2-trans-enoyl-CoA isomerase
- Acyl-coenzyme A oxidase
- Acyl-coenzyme A oxidase
- acetyl-CoA C-acyltransferase
- acetyl-CoA C-acyltransferase
- Acyl-coenzyme A oxidase
- Oleate-induced peroxisomal protein POX18
- Oleate-induced peroxisomal protein POX18
- methylmalonate-semialdehyde dehydrogenase
- Pot1-2p
Sequence:
MKKKIYINSMSYLYFSLSNSPKVSKLLYTMSDEEADVLYEVRDRTAIITFNIPSKLNALNGEQYLKLGKFMERANEEEGTVMTLIQSTGRFFSAGANFADNGLMDVDPQLLFTHEYWLGKFVARNVWLTNLFNDHKKILVAAVNGPSIGLSTGLLMLVDLVYVHDLSKFYLLAPFANLGLVAEGAASATLFARLGWSKASEALLLAKPISGADCYNVGLINKHYDGKFKSTEEFNQQVYKEVTDAFENLHEDSILQNKQLLKLNRDQYINHANSQEVMRGLGKWLEGVPQTRFVQLANKDVKHKI
Protein: Salicylate 5-hydroxylase, large oxygenase component (S5H large oxygenase component) (EC 1.14.13.172) (Salicylate 5-hydroxylase, oxygenase component NagG) (Salicylate 5-monooxygenase, hydroxylase large subunit) (O52379)
Organism: Ralstonia sp
Function: Oxygenase component of the salicylate 5-hydroxylase (S5H) multicomponent enzyme system which catalyzes the 5-hydroxylation of salicylate to gentisate. Active only on substrates with a ring-substituted carboxylate group with an adjacent hydroxyl group. Primarily active against salicylate and substituted salicylates, but not against 2-hydroxycinnamate, 3-hydroxycinnamate, 2-hydroxyphenylacetate, 3-hydroxyphenylacetate, 2-hydroxybenzophenone, 1-hydroxy-2-naphthoate, 4-methoxysalicylate or 2-hydroxyacetophenone.
Interaction partners:
Sequence:
MSEPQRLKPVFPQDPKWPGEGSSRVPFWAYTREDLYKRELERLFYANHWCYVGLEAEIPNPGDFKRTVIGERSVIMVRDPDGGINVVENVCAHRGMRFCRERHGNAKDFFCPYHQWNYSLKGDLQGVPFRRGVKQDGKVNGGMPKDFKLEEHGLTKLKVAARGGAVFASFDHDVEPFEEFLGPTILHYFDRVFNGRKLKILGYRRQRIPGNWKLMQENIKDPYHPGLLHTWFSTFGLWRADNKSELKMDAKFRHAAMISTRGQGGKNEEVVSGVDSFKEQMKVNDPRLLDIVPEPWWGGPTAVMTTIFPSVIIQQQVNSVSTRHIQPNGHGSFDFVWTHFGFEDDNEEWTQRRLIQANLFGPAGFVSADDGEVIEWSQEGFEQKPTHRTVIEMGGHEIGDTDHMVTETLIRGMYDYWRKVMGE
Protein: Melanopsin-like (Melanopsin) (Opsin-4-like) (Q1JPS6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Photoreceptor implicated in non-image-forming responses to light.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9QXZ9}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Period circadian protein homolog 2
- Cryptochrome 3
- Cryptochrome-1
- Aryl hydrocarbon receptor nuclear translocator-like 1a
- POU domain protein
Sequence:
MSHHSSWRGHHCAPGDINCTAGFKESLGSRNYKLLHVPVHGPTHSHHHDPPHPFPTVDVPDHAHYIIGSVILIVGITGVIGNALVVYVFCRSRTLRTAGNMFIVNLAVADFLMSVTQSPVFFAASLHRRWVFGERPCELYAFCGALFGICSMMTLTAIAADRCLAITQPLALVSRVSRRKAGAVLVVVWLYSLGWSLPPFFGWSAYVPEGLQTSCSWDYMTFTPSVRAYTILLFVFVFFIPLGIIGSCYFAIFQTIRAAGKEIRELDCGETHKVYERMQNEWKMAKVALVVIVLFIISWSPYSVVALTATAGYSHFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRVAIARYIPVLRPILRVKEKDLRSSFSSGSVSSRRPTLTSQCSLGVSMGNAARANGRWGKTRLSSASDSDSCWTESEADGSSVSSLTFGRRVSTEISTDTVILSSGSSVSNASGQKSERAHKVISVPVPSITFETDAADGESLSDGKALLGGN
Protein: Probable WRKY transcription factor 11 (WRKY DNA-binding protein 11) (Q9SV15)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Regulates rhizobacterium B.cereus AR156-induced systemic resistance (ISR) to P.syringae pv. tomato DC3000, probably by activating the jasmonic acid (JA)- signaling pathway.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223, ECO:0000269|PubMed:26433201}.
Interaction partners:
- Putative cysteine-rich repeat secretory protein 14
- Peroxidase 5
- RING-type E3 ubiquitin transferase
Sequence:
MAVDLMRFPKIDDQTAIQEAASQGLQSMEHLIRVLSNRPEQQHNVDCSEITDFTVSKFKTVISLLNRTGHARFRRGPVHSTSSAASQKLQSQIVKNTQPEAPIVRTTTNHPQIVPPPSSVTLDFSKPSIFGTKAKSAELEFSKENFSVSLNSSFMSSAITGDGSVSNGKIFLASAPLQPVNSSGKPPLAGHPYRKRCLEHEHSESFSGKVSGSAYGKCHCKKSRKNRMKRTVRVPAISAKIADIPPDEYSWRKYGQKPIKGSPHPRGYYKCSTFRGCPARKHVERALDDPAMLIVTYEGEHRHNQSAMQENISSSGINDLVFASA
Protein: NAC domain containing protein 64 (NAM-like protein) (Q9LXY7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Homeodomain-like transcriptional regulator
- Transcription factor HHO3
- Transcription factor TCP21
- bZIP transcription factor 11
- Ethylene-responsive transcription factor ERF113
Sequence:
MAIPQRNKRKARSSPERLTQPPELPHNSDVPSSSSSSAADNFFSWSTKQFAFPPGYRFVPKDQELIFHYLKPFSQGNKCSLLNVPIHRVNIYESNPQHLSEKYEKGNDKDWFYISERTKTGKAGRSNKRVDNGGYWSATVAAQKINAGNGIVGYKTSLEYYVGKQSNSVKGDWLMQEYWFESSDDNNNEKVDHALCKIYLTPAAAKKKKAEEAENEKLKKEEDVEQLDLNQPDQLQLQQPHDIVYQPQYCLLPEHHQPQPFPDNFSELISFQQQPVMIPDDFEDFLAEFTKPHSLDGDEEFNNYGLFEGFFDTEGMIKH
Protein: Sushi, nidogen and EGF-like domain-containing protein 1 (Insulin-responsive sequence DNA-binding protein 1) (IRE-BP1) (Q8TER0)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:33724335}. Note=Forms microfibrils within the extracellular matrix and colocalizes with fibronectin (FN1). {ECO:0000250|UniProtKB:Q70E20}.
Interaction partners:
- Somatostatin
Sequence:
MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYREATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGKLSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVETTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRDGADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARFGGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYRVHQDICFKESCESTSLKKTPNRKQSKSQTLEKS
Protein: PA domain-containing protein (Q384W6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MALWLRVVFTIVVALLGAAVPVTSLVVHRPLYLAKRNMLSTVPDYGTTPLTGRNNHGKVILVEMGALCNGDKVDPHWVDAVLLTHGGQCSHGTQAVRAQSAGAVGLLVANDGVGSADEAEVDIPVERITTKDYDAITNAVKNDVLVEVTLGTPLDVLRYIV
Protein: Calcium-dependent protein kinase 13 (OsCDPK13) (OsCPK13) (EC 2.7.11.1) (Calcium-dependent protein kinase OsCDPK7) (Q9FXQ3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity). May function in signal transduction pathways that positively regulate responses to cold, salt and drought stresses.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Os12g0541300 protein
- Respiratory burst oxidase homolog protein B
- Os11g0537400 protein
- Os09g0438000 protein.
- Os08g0453700 protein
- Serine/threonine-protein phosphatase BSL1 homolog
- Os01g0734333 protein
- Os01g0734200 protein
- Os01g0734466 protein
- Os05g0528000 protein.
Sequence:
MGNACGGSLRSKYLSFKQTASQRHDTDDNNNAAAADSPKKPSRPPAAAKTDDHPVSASAPAAAMRRGQAPADLGSVLGHPTPNLRDLYAMGRKLGQGQFGTTYLCTELSTGVDYACKSISKRKLITKEDIEDVRREIQIMHHLSGHKNVVAIKGAYEDQLYVHIVMELCAGGELFDRIIQRGHYSERKAAELTRIIVGVVEACHSLGVMHRDLKPENFLLANKDDDLSLKAIDFGLSVFFKPGQTFTDVVGSPYYVAPEVLLKHYGPEADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGFIDFDSDPWPVISESAKDLITKMLNPRPKERLTAHEVLCHPWIRDHGVAPDRPLDPAVLSRIKQFSAMNKLKKMALRVIAESLSEEEIAGLKEMFQTMDADNSGAITYDELKEGLRKYGSTLKDTEIRDLMDAADIDNSGTIDYIEFIAATLHLNKLEREEHLVAAFSYFDKDGSGYITVDELQQACKEHNMPDAFLDDVINEADQDNDGRIDYGEFVAMMTKGNMGVGRRTMRNSLNISMRDAPGAL
Protein: U5 small nuclear ribonucleoprotein 200 kDa helicase (A0A494C1A5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGR
Protein: Four and a half LIM domains 1 (A0A494C0D6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITAPTSGAGIRVERGLVPRGWWFFIEKIEA
Protein: Rap guanine nucleotide exchange factor 2 (G5ECE2)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MIVIDYPTEPQSNGMSPRTPPRGIHHSGEPVHQKTPRKSAPNMSVDSIAMPPPPVPPRPLRLPQTAAKGPAPLPPRGLPRTYPLDFPVDIPTTSSSSSNTSYNDQHRSQVYLNGLSADEDTLVRVKHRREKSNSVGGQAQNGISTARRLRGRSTASSTTTEGETASNEGADSDEDEGSMPSQESSSGGFMDLRDSVRECLEKEPSERNSEDLAVLLDFMQHMSAFAALPMSIKRQLCLKMVFAVVNDAGTVVLAHNEKLDSWSVIVNGCVEVVKPSGERVEYKLGDSFGAEPTPATQIHIGEMRTMVDDCEFVLVEHRDFCSIMSTIGDHIEKDRDGLTGEVVSEVERRTVGTHCGQVLIKGKPDKLIHHLVDERDHNVDPHYVDDFLLTYRVFIRDPTTIFEKLMLWFADSIYRDKVARLVLLWVNNHFNDFETNDEMWNLLERFEGALERDGMHSQLSLLNIACSVKAKPRQVILTRRKDDKMMMRLVGGQESGNSVYVAEVFPDTSAAREGVKRADEMLEVNQQSAKYLSAKKAEDLLTGSLSLTLMLKNNVLGYKETIGKIEHNKPKNGTSRSGAGIPMVIPVHKTSITGKKSSTTSSKSGMMEKLMTILKSSKEDSMDFTDEAKISSADLRPSRSNPDITSISQYYGPVRSECPEHVLKIYRNDQTFKYLPVYKETSAQNVVQLALQEFNMTAEGSPEWSLCECTVTIDGVIKQRRLPPQMENLAERIALNSRYYLKNNSRSEPLVPDELAPELLKEAQTQLLSLNAQVVAAQLTLQDFSVFSAIEPTEFLDNLFKLDSKYGSPKLEEFEQLFNREMWWVATEICTERHVQKRAKLIKKFIKVARYCRDLRNFNSMFAIMSGLDKPAVRRLHSSWERVSSKYIRMLDEIHQLVDPSRNMSKYRQHLAEVAQEPPVVPIYPVIKKDLTFAHDGNATYSEKLINFEKLRLIAKSIRGVMKLSSAPYEIASMAERSGGVVMDALLHMNSFENSNVATMRKGMSGKQNQPRKKVYEQALMVRKVKSYLEGLHVVDNEMELDSMSYDIEPQVQTAHRGANSSSTANIRRVPSPTPSSLSSQSAGSADQSSRHRLLFNGTGSISSAGGGSKFGVESPQAVQKMLSLVQNSKVKGAPPQITSPSTSARSSLQRNMPRVTGRQATSSAQGPVQLNEETSTVTTYYQSDVLI
Protein: Collagen, type VI, alpha 1 (F1Q6P3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Collagen alpha-2
- Collagen, type VI, alpha 3.
- Decorin
- Integrin alpha-2 isoform X1, tandem duplicate 2)
- Integrin alpha-5 precursor
- Collagen, type VI, alpha 3.
- Uncharacterized protein.
- Integrin beta
- Integrin, alpha 1
- Integrin beta
Sequence:
MALNGYILTALCALWAGIFAQDVSRSSFRECPVDLFFVLDTSESVALRAKPPEFYINQIKTFTKLFIDELKDLRQPCDRDVTWNSGALHYSDDTELVMGLVDLNTKRADLKAAIDRIKYIGKGTYTDCAIKEGIAELLRAGSHYHENKYIVVVTDGHPITGYKEPCGGIQEAANEARQHAIKVFAVAISPDQEDTRLSVIATDINYRQNFTAADNSRSTQMSTIRSIIHMITNETKDVCCSFDCIADGGPQGPPGDPGQRGETGRPGMPGEKGDFGAQGNPGDPGPVGYQGMKGDQGIKGDKGERGHKGFKGDKGHHGLDGTDGRKGEPGFPGLPGCKGSPGPDGLQGESGPKGDPGQYGRKGERGDPGRDGEPGRPGNYGPSGAKGDRGPRGANGDKGERGDDGPPGPDGPRGERGQGGEKGEQGSRGNRGPRGEPGEPGPRGEQGREGSSGANGEPGEQGRAGQPGYRGDEGPAGPEGDKGPRGIKGAPGDRGLMGERGEDGPPGNGTEGCAGFQGYPGPRGDPGAPGGKGTPGPKGDDGEPGDTGLDNDRLGPPGTKGAKGHRGPEGKPGPPGPPGPQGADECEILDIIMKMCSCCECTCGPLDIAFIVDSSESIGASNFAISKEFIVTIMDRLKLRQFGANESRIGVVQYSGEKSQEVVQLGDPNIKTLTDLKQAVKDLRWLAEATYTGEALQYSLRNMLSKLITERSVVLVLTDGRSDTIRDKVPLNVLCGKGFKVGGVGVTDYAERKPNPEQLDEVVCKDDPRKGFSFVLNNFGLLLDDNFLQNLTEKICEDKKCPTYTCPISFNDNTDVLIMMDSSASVGAKNFEMTKDFSRMLAKRFLSAERGNFQVRIGVGQYSNNANLEAEFSTNATQVVAQIADAKFQNAGTQVTNALNFAIERFRGGRTRKKKLLVFSDGRSQGVNSIQIEKAVEQVSNAGIELYVLAVGNQVNEAHLRTLVSRGRPYDNTYAYRHLFKVPDYRSLVTGVFYQTVSRKISLETRG
Protein: MYB transcription factor 69 (ZmMYB69) (Myb-related protein 306) (K7TLS0)
Organism: Zea mays (Maize)
Function: Transcription factor that binds to the promoter of MYB31 and MYB42 and activates directly their expression, thus repressing lignin biosynthesis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:35640133}.
Interaction partners:
Sequence:
MGRPPCCDKAGVKKGPWTPEEDIVLVSYVQEHGPGNWRAVPVSTGLMRCSKSCRLRWTNYLRPGIRRGNFTPHEEGIIVHLQALLGNRWAAIASYLPQRTDNDIKNYWNTHLKKKLRKQQAIGAIFAPPRPSEPTAGHADCRRHDMTRSSKDSHAACPADSTPAADEVVTQLIAQQFAATDGDTSSSSSYSYASSTDNISKLLNGFMMKSASPARDDATDTIKTSSAIDIDPFDHKSGGAALPPPKKRQQQQHLSSIENWLFDDATEQLVVQLMEEISGGSCSVPMLLY
Protein: CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Menage a trois) (RING finger protein MAT1) (A0A8I5ZYY1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR003338}.
Interaction partners:
Sequence:
MADSANAASCNVGKYPHVCTWWLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLENTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQESEQRRLFIQKEEELQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKSMKPVTFSTGIKMGSLISLAPIQKLEEALYEYQPLQIETCGPQVPEQELLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPR
Protein: Peptidyl-prolyl cis-trans isomerase FKBP16-4, chloroplastic (PPIase FKBP16-4) (EC 5.2.1.8) (FK506-binding protein 16-4) (AtFKBP16-4) (Immunophilin FKBP16-4) (Rotamase) (Q9SR70)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular location: Plastid, chloroplast thylakoid lumen {ECO:0000269|PubMed:11826309}.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic
- Photosynthetic NDH subunit of lumenal location 2, chloroplastic
- Thylakoid lumenal protein TL20.3
- Peptidyl-prolyl cis-trans isomerase CYP28, chloroplastic
- Peptidyl-prolyl cis-trans isomerase CYP26-2, chloroplastic
- Thylakoid lumenal 17.4 kDa protein, chloroplastic
- Plasma membrane fusion protein
- Protease Do-like 8, chloroplastic
- Peptidyl-prolyl cis-trans isomerase FKBP20-2, chloroplastic
- PsbP domain-containing protein 6, chloroplastic
Sequence:
MILTMKLVHPLHHSLSSSIPFPSRKRQSKPYRCSLPSPGCEKVIRTETVLPPAPVSCEGRRVLLGCLLATASGILSTGSAEAVSTSRRALRASKLPESDFTTLPNGLKYYDIKVGNGAEAVKGSRVAVHYVAKWKGITFMTSRQGLGVGGGTPYGFDVGQSERGNVLKGLDLGVEGMRVGGQRLVIVPPELAYGKKGVQEIPPNATIELDIELLSIKQSPFGTPVKIVEG
Protein: Cysteine-rich perinuclear theca 4 (Cysteine-rich perinuclear theca protein 4) (Q6P925)
Organism: Mus musculus (Mouse)
Interaction partners:
- Cysteine-rich perinuclear theca 12
Sequence:
MTRVAKKVHWSRAATAAAAAAKAKRSKLKKKRNPRSKLPKRSRHSLIRSHSRSCCCCLRSRSRTTLKITKKGEQSLRRRIRRRIKRATELRLMRSQMEQSQRELIEPEPTEPLEPNEITVALFSHENANVSEPEEVPPYLDRDLAPNGELANS
Protein: Zinc finger protein XFDL 156 (Q9PST7)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MMHLIRNWPEKEKQNLNGSEMSRMKKIIEVGSERENIWGNLSQTQTHKESYRTPNQNYTSPMPQEYSYNGKLFALQREKLHNTNVQVIRMPNIAKQPKFNREIRSDSPKRKKAKSSEKSHVANISHQGTKINKFSKAQSALKSFICPICKRRFCNARNLLTHQRIHTGRRFVCSKCGKCFSNKKILIAHRWLHTGRKPFTCTKCNKGFLWNRDLQKHEKSHKEMRNKSLGLVHRHDKLREVSTDPCKREKSFDCTECGKSFKRKSKLKTHFLCHTGEKPFVCVHCGKGFRDNYKLSLHLRIHTGENLSVCPDCGKSYTDKNKLIVHMRIHTGEKFMCSECGKGFSDFYNLKSHLQIHTGEKPFVCPECGKSFLSKYEFKSHLLIHTGKYPFICSECGKSFMDKRYLKIHSNVHSGNTFPCTECGKSFAAKQNLKRHQKIHTGEKPHKCTECGKQFLQKNKLDRHHLSHTGVKPFSCFECGEQFTWKHLLQYHQLSHTGERPFVCSECGKGYKTKASLALHCHIHTGEKPFVCPECGNSYRSNGALRYHLQTHIKGKYFAHSEHGESDKSETNE
Protein: Ras-related protein Rab-18-B (EC 3.6.5.2) (Q6DHC1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts (By similarity). Plays a role in apical endocytosis/recycling (By similarity). Plays a key role in eye and brain development and neurodegeneration.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9NP72}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:Q9NP72}. Lipid droplet {ECO:0000250|UniProtKB:Q9NP72}. Apical cell membrane {ECO:0000250|UniProtKB:P35293}.
Interaction partners:
- RAD50 interactor 1.
- Rab3 GTPase-activating protein catalytic subunit
- RAB3 GTPase-activating protein subunit 2
- Zw10 kinetochore protein.
- TBC1 domain family, member 20.
- Syntaxin-18
- ATP-dependent zinc metalloprotease YME1L1
Sequence:
MDDDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTIAIDGNRAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTKRDTFTKLENWLNELETYCTRNDLVKMLVGNKIDKDNREVDRNEGLKFARKHSMLFIEASAKTRDGVQCAFEELVEKILQTPGLWESSIQNHGVQLSDNEPQRQGACGGYCSLV
Protein: Protein X (HBx) (Peptide X) (pX) (Q4AE16)
Organism: Hepatitis B virus (HBV)
Subcellular location: Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04074}. Host nucleus {ECO:0000256|HAMAP-Rule:MF_04074}. Host mitochondrion {ECO:0000256|HAMAP-Rule:MF_04074}. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes. {ECO:0000256|HAMAP-Rule:MF_04074}.
Interaction partners:
Sequence:
MAARVCCQLDPARDVLCLRPVGAESRGRPISGPFGPLPSPSSSAVPANHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNARQVLPKVLHKRTLGLLAMSTTDLEAYFKDCLFKDWEELGEEIRLKIFVLGGCRHKLVCPPAPCNFFTSA
Protein: Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) (P04897)
Organism: Rattus norvegicus (Rat)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Membrane {ECO:0000250|UniProtKB:P04899}; Lipid-anchor {ECO:0000250|UniProtKB:P04899}. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody (By similarity). {ECO:0000250}.
Interaction partners:
- D
- Adenosine receptor A1
- Guanine nucleotide-binding protein G
- Regulator of G-protein signaling 9
- Guanine nucleotide-binding protein G
- Apelin receptor
- Regulator of G-protein signaling 3
- P2Y purinoceptor 12
- Beta-2 adrenergic receptor
- Lysophosphatidic acid receptor 1
Sequence:
MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPQRADDARQLFALSCAAEEQGMLPEDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITQSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
Protein: E3 ubiquitin-protein ligase TRIM35 (EC 2.3.2.27) (Hemopoietic lineage switch protein 5) (Macrophage-derived apoptosis-inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Q8C006)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response (By similarity). Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via RIG-I signaling pathway. Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2. Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling. Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway. Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12692137}. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies in transfected COS and HeLa cells. {ECO:0000269|PubMed:12692137}.
Interaction partners:
Sequence:
MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPSCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKAFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATLDAMKEESRKKHLQAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPTWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAHFGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI
Protein: Forkhead box protein D3 (HNF3/FH transcription factor genesis) (Winged-helix protein CWH-3) (P79772)
Organism: Gallus gallus (Chicken)
Function: Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor SOX-10
- Uncharacterized protein.
- Paired box 3
- Zinc finger protein ZIC 1
- Homeobox protein GHOX-7
- Transcription factor SOX-9
- TF_AP-2 domain-containing protein.
- PAX7 protein
- Transcription factor SOX-2
- Transforming protein p68/c-ets-1
Sequence:
MTLSGGGSDMSGQTALAAEDVDIDVVGEGDDAPGKDGDGEARSPAALPLPLDEAAEPGEPERAARRAAAARQPGPGRPEGGRGGGGGGGGGEEGASGGGAAAAAAAGQSKPKSSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLRDQTALMMQGFGAYGLAGPYGRPYGLPPGAYPHPAALQYPYIPPVGPMLPPACPLLPSGELSRKAFNAQLGPSLQLQLSSLGAAGSIVKSEPSSRPSFSIENIIGGPAASSAPSAQTFLRPPVTVQSGLVAHQPLALARTTAAIAPILSVPTNIIAGQFLQPPAAVQAKWPAQ