wanglab/gogpt-training-data huggingface dataset:
Protein: Lectin ADEL (C0HK25)
Organism: Aplysia dactylomela (Spotted sea hare)
Function: Binds in decreasing order of affinity: galacturonic acid, D-galactosamine, methyl-alpha-D-galactopyranoside and further galactose-containing carbohydrates. Has hemagglutinating activity against human and rabbit erythrocytes.
Interaction partners:
Sequence:
DPDKCKTIRVESWSYKYAEKVVEDASYVLNMTVVDRQSAAACTLGESFGYQKATLWVDHGCRADFKVCYLPVMPTECQTLRVESWNYKYAEKVVEGAALFINMTVEDRQSEASCDLDKSFGFYNQNSTVWVNHGCRADFNICYLKGAVTTSTINVSSWNYQYATKVLPAASCIYSMRVVNQQSAAPCTLGTTYGFVANTMWVDDGCRADFKPSYYSP
Protein: Factor of DNA methylation 1 (Protein IDN2 PARALOG 1) (Protein IDN2-LIKE 1) (Q9S9P3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Forms a complex with IDN2 and FDM2/IDNL2 that is required for RNA-directed DNA methylation (RdDM) and that functions at a downstream step of the RdDM pathway. Required for de novo DNA methylation and 24 nucleotide small interfering RNA (siRNA) accumulation. Binds unmethylated but not methylated DNAs through its coiled-coil domain. May bind double-stranded RNAs (dsRNAs) with 5'-overhangs through its XS domain. However, according to, FMD1 does not bind dsRNAs.
Interaction partners:
- DNA
- Protein DEFECTIVE IN MERISTEM SILENCING 3
- Protein RNA-directed DNA methylation 3
- DNA-directed RNA polymerase V subunit 1
- Protein SUPPRESSOR OF GENE SILENCING 3
- Rab3 GTPase-activating protein catalytic subunit
- Protein RDM1
- DNA-directed RNA polymerase IV subunit 1
- Protein CHROMATIN REMODELING 35
- Protein MICRORCHIDIA 6
Sequence:
MSISDEEAEISESEIEDYSETPYRLLRDGTYKVKVNGQLRCPFCAGKKKQDYKYKELYAHATGVSKGSATRSALQKANHLALAMFLENELAGYAEPVPRPPVVPPQLDETEPNPHNVYVWPWMGIVVNPLKEADDKELLLDSAYWLQTLSKFKPIEVNAFWVEQDSIVGVIAKFNGDWSGFAGATELEKEFETQGSSKKEWTERSGDSESKAYGWCARADDFESQGPIGEYLSKEGQLRTVSDISQKNVQDRNTVLEELSDMIAMTNEDLNKVQYSYNRTAMSLQRVLDEKKNLHQAFADETKKMQQMSLRHIQKILYDKEKLSNELDRKMRDLESRAKQLEKHEALTELDRQKLDEDKRKSDAMNKSLQLASREQKKADESVLRLVEEHQRQKEDALNKILLLEKQLDTKQTLEMEIQELKGKLQVMKHLGDDDDEAVQKKMKEMNDELDDKKAELEGLESMNSVLMTKERQSNDEIQAARKKLIAGLTGLLGAETDIGVKRMGELDEKPFLDVCKLRYSANEAAVEAATLCSTWQENLKNPSWQPFKHEGTGDGAEEVVDEDDEQLKKLKREWGKEVHNAVKTALVEMNEYNASGRYTTPELWNFKEGRKATLKEVITFISNDIKILKRKRT
Protein: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein) (Q8WZ19)
Organism: Homo sapiens (Human)
Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:11593007}.
Interaction partners:
- Cullin-3
- UBX domain-containing protein 7
- FAS-associated factor 1
- BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
- BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3
- BTB/POZ domain-containing protein KCTD17
- Kelch-like protein 22
- Kelch-like protein 20
- Kelch-like protein 9
- Kelch-like protein 21
Sequence:
MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD
Protein: Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (dTDP-glucose pyrophosphorylase) (dTDP-glucose synthase) (A0QPF9)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Involved in the biosynthesis of the dTDP-L-rhamnose which is a component of the critical linker, D-N-acetylglucosamine-L-rhamnose disaccharide, which connects the galactan region of arabinogalactan to peptidoglycan via a phosphodiester linkage.
Interaction partners:
- dTDP-glucose 4,6-dehydratase
- dTDP-4-dehydrorhamnose reductase
- dTDP-4-dehydrorhamnose 3,5-epimerase
- dTDP-4-dehydrorhamnose 3,5-epimerase
- UTP--glucose-1-phosphate uridylyltransferase
- Phosphoglucomutase, alpha-D-glucose phosphate-specific
- Glucose-1-phosphate thymidylyltransferase
- UDP-galactopyranose mutase
- dTDP-RhA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase
- Membrane protein
Sequence:
MRGIILAGGSGTRLHPLTIGVSKQLLPVYDKPLVYYPLSTLIMAGIRDILVITTPADAPAFRRLLGDGSDFGVNLSYAAQNEPEGLAQAFLIGADHIGNDTVALALGDNIFYGPGLGTSLRRFEHVSGGAIFAYWVANPSAYGVVEFDADGKAVSLEEKPKTPKSHYAVPGLYFYDNTVIDIARSLKKSARGEYEITEVNQIYLNRGQLSVEVLARGTAWLDTGTFDSLLDASDFVRTIELRQGLKVGAPEEIAWRAGFIDDDQLATRAKELLKSGYGHYLLQLLDRE
Protein: Alpha-crystallin B chain (Alpha(B)-crystallin) (V9HW27)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Lysosome {ECO:0000256|ARBA:ARBA00004371}. Nucleus {ECO:0000256|ARBA:ARBA00004123}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
Protein: Variant surface glycoprotein (VSG), putative (Q57X38)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MRLAATLLILCLASAPPGKTTNNQPLKTTPWKNLCDVYAAFKDRMAGTKLAQQKHRQLSLDMGLQQTRTQILQQSTSDAQTRRRFAVLASYLSFEAAAARKHTEGKTEPAFWNNLENAAKLLGQIKEFLTIAAGPRQANTKGCITTNDGSEATGLKQGLTELAQAHGGCKAQIGDDPTGVAANDIIDDNGLKKYETAAPAQTTTGETGCKLLTLGNNNGYVDGTSLGTGVEVAGGLLKITPTVTNERKLNDLATNPGAGSKAAIAEAWKGFSSPTTPVAGYTNKGISALKTEQHFKLAFRIVYGVTPETTEKQLQDQIDTVFGKDPANFTNNNWKLVEEYTLPKDTAGKPAGTQLKEIKEPAVLKQILSETLHDREVREQKQQAELLEAKRQLQAQNKSETAKEAAEAKCNKIDKDTECKTPCKWNAEAQDEAKKCTLSEKGQKTAEKANQEGKGAKTTNTTGNNSFVIHKAPLLPAFFLR
Protein: Transcription factor Sox-7 (xSOX7) (O42342)
Organism: Xenopus laevis (African clawed frog)
Function: Transcription factor. Binds to the DNA sequence 5'-AACAAT-3'. Acts downstream of vegt and upstream of nodal signaling to promote endodermal and mesodermal differentiation by promoting vegt-induced expression of both endodermal genes (including endodermin) and mesodermal genes (including snai1/snail and snai2/slug). Induces expression of multiple nodal genes (including nodal, nodal2, nodal4, nodal5 and nodal6) and binds directly to sites within the promoter of the nodal5 gene. The endodermal and mesodermal specification pathways then interact to initiate cardiogenesis. Acts partially redundantly with sox18 during cardiogenesis. Also acts as an antagonist of beta-catenin signaling. Regulates (possibly indirectly) development of the pronephros, the functional larval kidney.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MTTLMGSYSWTESLDCSPMDGDLSDGLSPHRSPREKGSETRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALSPAQKRPYVEEAERLRVQHMQDYPNYKYRPRRKKQIKRICKRVDTGFLLGSLSKDQNSVPDTRGCRTAMEKEENGGYPGAALSDIRHYRETPSNGNKYDQTYPYGLPTPPEMSPLEAIDQDQSFYSTSCSEDCHSHINGAVYPPEYSRSPILCSHLSQVPIPQPGSSMIPPVPTCPPAYYSSSYHSIHNYHAHLGQLSPPPEHPHYDTIDQISQAELLGEMDRNEFDQYLNTSLQDPTEMTIHGHVQVSQASDIQPSETSLISVLADATATYYNSYSVS
Protein: Vacuolar protein sorting-associated protein 16 homolog (Q6GMQ7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPWLWTAPHQKESQKADEYLREIQELGQLTQAVQQCIEAAGHEHQPDMQKSLLRVGLDGRAGEGGAGRGWDGQQGSSLLSPSGSSQAASFGKCFLDRFPPDSFVHMCQDLRVLNAVRDYHIGIPLTYSQYKQLTIQVLLDRLVLRRLYPLAIQICEYLRLPEVQGVSRILAHWACYKVQQKDVSDEDVARAINQKLGDTPGVSYSDIAARAYGCGRTELAIKLLEYEPRSGEQVPLLLKMKRSKLALSKAIESGDTDLVFTVLLHLKNELNRGDFFMTLRNQPMALSLYRQFCKHQELETLKDLYNQDDNHQELGSFHIRASYAAEERIEGRVAALQTAADAFYKAKNEFAAKATEDQMRLLRLQRRLEDELGGQFLDLSLHDTVTTLILGGHNKRAEQLARDFRIPDKRLWWLKLTALADLEDWEELEKFSKSKKSPIGYLPFVEICMKQHNKYEAKKYASRVGPEQKVKALLLVGDVAQAADVAIEHRNEAELSLVLSHCTGATDGATADKIQRARAQAQKK
Protein: Kinesin-like protein (Q386M3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Kinesin motor domain-containing protein
- Chromosomal passenger protein
- Chromosomal passenger protein
- Aurora kinase
Sequence:
MSIEVHVRIRPNAPTSVWSSAETVLYSTNNPDVRYVYNKVHHGGTSNHTIFQGLEALVHAGFGGKNVTVMAYGQTGSGKTHSMNGTAADPGIVPRTALLLFELKKNSPGTEIFVYFTEIYNESVKDLLDPQRGDLALHDAPDGGVYFDKKSVLLDSLEGFTKLQGAAERNRKYGVTNLNDHSSRSHMILTFEIHRSSRQVSTINLVDLAGSESASRANTEGMLLREGGFINKSLLTLGNVVDAIVDKRTYVPYRDAKLTRILRNCLGGSGMTFILCCINPSTENFEQTVSSLRFTQRAMKIKNDPVMVLNMPPLFAHEYSIGAEEIVRGIDELSDAYYQRGLRDAYLYVDKTVSSIVGSFKGQVSEPIRAMADAQRLLIAHDHSVAIDQIGPLYSRLEELTQQQRQDRDIEEREGKRQRQIEDEIECRRNKVARLEARVKERDAEGDTELANWEYQLYEARQRRVTQLELLLSSEKAARCQLQYKHVICIERIAARWVPMIKSLGPATPPVADKKVALQRLRQRLEQAREELQDLTVAHDMIKDDLPNVQAAAEGAGGGTLTPTSLSPRPQMSEDAIPIGAHMSDAQIEERIHQLEREEKLLMSQAIHVARCESARRVRESLASPRRETPRTSRSVVRLHSATPSRQDKDAGDMRGQLLEVLDSSPLDIAHRSRCHGSQAHQRSPTPRTARTVFPTADEELCDDVNVPVGPKRSASPRTENLADGMRRALGVLRDVRSKLLRPALGRNVPSVSRGSARAALRTSSPLPQYVRSGSLSGRRTNSSPPINIEENNGDDEAMPFSDVCKQRNNAKIQEPVIGIAARRRLEGAPTRPNVERALWRLSLSPSSERAGKSGRSRSRRR
Protein: ATP-dependent DNA helicase MER3 homolog (EC 3.6.4.12) (Protein RICE MEIOTIC CROSSOVER 1) (B6DMK2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: DNA helicase required for crossover formation, complete synapsis of homologous chromosomes and bivalent formation during meiosis. Is specific to recombination events resulting in interference-sensitive crossovers (class I meiotic crossover). Works cooperatively with ZIP4 to promote crossovers.
Subcellular location: Nucleus {ECO:0000269|PubMed:22393242}. Chromosome {ECO:0000269|PubMed:22393242}. Note=Detected in punctuate foci onto the chromosomes in prophase I meiocytes. {ECO:0000269|PubMed:22393242}.
Interaction partners:
- Os06g0167000 protein
- Os05g0163250 protein
- CUE domain containing protein, expressed
- Os01g0263600 protein
- Os10g0498600 protein
- DIM1
- Thioredoxin-like protein 4B
- Sm protein F
- Sm protein F
- Small nuclear ribonucleoprotein Sm D3
Sequence:
MAAMGHLGDPYALRSVADLPPPFRSVFGFRYFNSLQSECFPACFLSDVNMVISAPTGSGKTVLFELCILRLLSRFLSSEWRFNLIKGTLKTIYIAPMKALVQEKLRDWNMKLGSLGISCLEMTGDNEFYNTKSIHDADLILTTPEKFDSVSRHGIRDGGLGFFSDIALVLIDEVHLLNDPRGAALEAIVSRIKMLSRLGTMKIAPLANVRFIAVSATIPNIEDIAEWLAVPSEGIKRFGEEMRPVKLTTKVFGYAPARNDFLFERRLQSFIFDILMQHSRGKSALVFCSTRKGAQEAAQCLSQTASSLGYSNPFMKSMQQYEHLKEAALTCSDKQLQACLVHGVGYHNGGLCLKDRSVVEGLFLKGDIQILCTTNTLAHGINLPAHTVVIKSTQFFNKEKGLYVEYERSMVLQMCGRAGRPPFDDTGTIIIMTRRETVHLYENLLNGCEMVESQLLPCAVEHLNAEIVQLTVSDITLAIEWLKCSYLYIRIKKNPQHYGIKKEIPRELLEKQMKDICVEKIHELGEYGLIWTDEDGFLLKPLEPGRLMTKFYLKFDTMKLIVKASACCTLEDLLHIICHSAEITWIQLRRNEKKLLNEINADKEGRLWFHVVGANGKRKKRIQTREEKIFILANDCLTGDPLVHDLSLNQEMNSICSNGCRVAKCMREYFIYKKNYKSAISSMLLAKCLHQKLWESSPFLLKQLPGIGIVTAKALKTAGIDSFESLATADARKIESVTGRNYPFGDSIKSYLPSLGPKIDINIEDAGNRQGKSTIIVTLTRLSQAVGSSKQNYADMVVGSEEDNAILFHEKIKTQEFSSPYSVKLYVPCPPNARATLKVDVIFEEYVGLDIHKKHVVSREDFHVTKVFGIKKAEPLYNLPAESCLVSSKTTRTNQSKYHNGQNPLSKEVCVIEDDFRAKAPDKDDNDLEILGTREYNNLASLEAPSFTLLHEEDYEDVPDVLASEPVEAECKSATNNTIFDHIRKKSRDFPNLMLSKSMDSSYEPLILKKMKTSGDQFGLDQSSLHAYEVTPMVFDRTEARVSPNNTDERCRNILTRTAETRSFQFTGKMDSISQKSEILNRTQGKNSTQLAGKKAFEKSKTPDENSLHFVGKRDSSSEKSKALSKTPDENSLQFLGKMDSSSEKSKFCFSSPLADFQPMQCTKQVAASVQPLTIQDYCKDILASAKSSGTGASFLDVKSVFSFL
Protein: Cytoadherence linked asexual protein 2 (O96279)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MVSSVKSSLFLLIFFLYLKKNVICSINDNVNENITEGLDEYEFGNENINESITENVNVNVTENEKDNLIYNDDNNNIEELKSMIGNDELHKNLSILEKLILDSLKKDKLKLPLIKEGTEEYLDISKFKKKILTDSDDKTYILPTLESSFYDITKYEHILKEQLIEEYNSKISDAVKKKLLIVRTLKTIKLMLIPLNAYKEKNDLKIALEELNNVITHRTYETLKKSPIENPGEFFRKLLTHVKEVKESKEIENKGEYLILGNDKIEIMDAHDFFFTTNSNIKFMETLDSISNQYGLGLINDLGPHLIALGHFMVLKLALKNYKNYFEAKNTKFFSWQKILEFSLTDRFKILDMMCDHDVVYYSQDKRRKTYLNVDTSGSSMECNILEFLIHYFNKYQLEIIKATQDTDFELHGMMEHKNIKDYFFSFMCNDPKECIIYHTNQFKKEAKEENTFPEEPNREISAYNLYLNYYYFMKRYSSYGIKKTLYVHLLNLTGLLNYDTRSYVTSLYLPGYYNVVEMSFTEDVEFTTLFNNLLKCIKKCHKEETNTNTSLMDSNSSHNYFLHEITKCDLCKGAFLYSNMKFEEVPSMLQKFYIYLTEGLRIQKVSFLMKTLDIYQDYSNFLSHDINWYTFLFLFRLTSFEEISKKSVGEAMYLNIQDEDSFHKTITTNYWFPSPIKKYYTLYVRKHLPNNLLDELEKLMKSSTLEKMKKSINFLVHVNSFLQLDFFHQLNEPPVGLPRSYPLSLILEHKFKEWMNSSPAGFYFSNYHNPYIRKELHRKVLTEKFEPPKMNKWNEVLKSLIECAYDMYFEQRHVKNLYKNHNIYNINNKIMLMRDSVDLYKKNFKDVIFFADIFNLRKYLTATPLIKKTWDRMYYFIYRNTGNSVNFYKYGIIYGFKINKVYLKEVVDELYSIYNFNTDIFSDTSFLQTVYLLFRKIEDSYRTHRRNDHIGVNNIFFMNVANNYSKLNNEEREMEIHNSMASRYYSKTMFAAFQMLFSTMLSNDANNLDKVYGKSSNIQVATSTTAFLTFAYVYNGSIMDSLTNRLLPPYAKKPITQLKYGKTFVFSNYFMLASQIYEMLNYKNLSLLCEYQAVASANYYSAKKLGQFVGRKYFPLTTYYLSLRIRASYGWVHGTETKICNSEGVSCSRKGPTPGKFFFNWKSDAPIYLYFYFFSNLYLDSAKYFPGGFSTSLKEQTEHVSQKGFKKKPMVHELTKNLILDVTNGFMYAFCFYSIMPLYAYFENVNFYIISNFRFLDRYYNAFNKYFINFFKTKLKKYTTDVFIKYEYDAYTSMKKYGYLNEVIGSRLSSKNRIVKYIYDSNDDIMNNLRRYDMENRFRNKMSTYVDEYAFFDDCGKNEVFLNDRCDYCPIVEDLCEPDTKEYQPHTSNIQKVTDKNTTYINYEKLHEESYSQETQSDNTDDEKDNDLPDTELMITRLQ
Protein: mitogen-activated protein kinase kinase (EC 2.7.12.2) (Q582A4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDHKTATVDGSIPGNIYSCASAQLHNVTSNPEESPSSCNGVLSATAIGRQVKQRPPPLFSLTPPSLLPPTEPLHIPSSLQLTAHASSTVTPKRDRFQQLRPPLLNRSACSTAAGASVASLNMLAPEDFFGHHPRAQWISLSDDGQHLHVGPFIVSGDGCLTMESVLQLNANLGIHGGEVSPAPLGSHGRRSVPGALLKPKLSLTTEPLSNNSFTLLSTSLDTPYSPITYSLNAHNAKTSGFTTPRPTFAAAGGDSATHTYVMPSFNLPSPSVLPPNNADSSSSNEPGLTAVKYSDVKLKSIVGEGASANVYMAEHYPTGKLLAVKRIDLSSMIYGWEHMNICRTHSVRASPYIRQLHRFVLRELQTLHMAYRNPFMVKVYNAFFNKEEMALDFVMEYMHYGGLDRLQRLLGGYVTDNDVSNGVSTGNDVNCQVVSAGGSRTKKRQNQNGGTHGARRRNRSNRHNGDGAVCMTEEKEMRESEVDAKDERKVVSVPERLVAVVGEQLLRGVEHMHSRGFVHRDIKPGNVLINNRGIVKLGDFGLSSRCTGEEESVVSLPHFPADFIASGDTGADVKIKSRDDSCEERRCNPRVNNKRGSVDNGFESDAASNMSGNGYGHSINGIHTGSGYESPPLVGVASASESGAATGDDPQCSGTSKYMSPERQRGRPHGKPSDIWAVGMTLAEFAVGQYPVDLTDCADPFVTIHRMEEPLDLRRFPRDVPLSDAFLDFIHSCMDPEPRRRPTARELLSHPFFRQWTTTFSIEAYLELHTAGCSNLQKR
Protein: Coronin-1B (Coronin-2) (Q9BR76)
Organism: Homo sapiens (Human)
Function: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16027158}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:16027158}. Note=Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers. {ECO:0000269|PubMed:16027158}.
Interaction partners:
- Coronin-1C
- Coronin-1A
- Coronin-6
- Actin-related protein 2
- Src substrate cortactin
- Protein jagged-2
- Hematopoietic lineage cell-specific protein
Sequence:
MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGRMENGDA
Protein: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] (P25114)
Organism: Rattus norvegicus (Rat)
Function: Synthesis and degradation of fructose 2,6-bisphosphate.
Interaction partners:
- Fructose-1,6-bisphosphatase isozyme 2
- ATP-dependent 6-phosphofructokinase, platelet type
- Hexokinase-2
- Fructose-1,6-bisphosphatase 1
- ATP-dependent 6-phosphofructokinase, liver type
- Hexokinase-3
- ATP-dependent 6-phosphofructokinase, muscle type
- Mannose-6-phosphate isomerase
- Hexokinase-4
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
Sequence:
MASPRELTQNPLKKIWMPYSNGRPALHASQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDMVKTYKSFEFFLPDNEEGLKIRKQCALAALNDVRKFLSEEGGHVAVFDATNTTRERRAMIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEEQDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVWTSQMKRTIQTAEALSVPYEQWKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEELPYLKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPSEEALVTVPAHQ
Protein: NF-kappa-B essential modulator (C9JN51)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVV
Protein: Kinetochore protein SPC24 (Q04477)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:11179222, ECO:0000269|PubMed:11266451, ECO:0000269|PubMed:11952896}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:11179222, ECO:0000269|PubMed:11266451, ECO:0000269|PubMed:11952896}. Note=Associated with kinetochores. {ECO:0000269|PubMed:11179222, ECO:0000269|PubMed:11266451, ECO:0000269|PubMed:11952896}.
Interaction partners:
- Kinetochore protein NUF2
- Kinetochore protein SPC25
- Kinetochore protein NDC80
- Kinetochore-associated protein DSN1
- Inner kinetochore subunit CNN1
- Outer kinetochore KNL1 complex subunit SPC105
- Kinetochore-associated protein MTW1
- Kinetochore-associated protein NSL1
- DASH complex subunit ASK1
- Protein STU2
Sequence:
MSQKDNLLDNPVEFLKEVRESFDIQQDVDAMKRIRHDLDVIKEESEARISKEHSKVSESNKKLNAERINVAKLEGDLEYTNEESNEFGSKDELVKLLKDLDGLERNIVSLRSELDEKMKLYLKDSEIISTPNGSKIKAKVIEPELEEQSAVTPEANENILKLKLYRSLGVILDLENDQVLINRKNDGNIDILPLDNNLSDFYKTKYIWERLGK
Protein: Cadherin-86C (Q9VGW1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Protein crumbs
- Patj homolog
- Protein lin-7 homolog
- Protein PALS1
- Atypical protein kinase C
- LD29223p
- Zyx102 protein
- Exocyst complex component 2
- Protein limb expression 1 homolog
- Moesin/ezrin/radixin homolog 1
Sequence:
MASTSSSQPEKNRSHVPLCRLGTEPVSRTGAAEEPSGQRECYYYAPATSPHHHHHHHHQHHHHHRLKQHHRHHHHHHRLQHHHHHHQQQHNHQNQQMQHHWPSRLGPIGPWLGAMTAYRLLTISLLIGILCPHHVQGADPKFDPTTRMRLVLVPADAQVNSVIYRLRATDEEFDYPLTFEFVGDASASTVKVESLPCTKYNSVCQANIVLQRRLEPGRYYDFQVSVKDTKGGMTTQLCSITATNFTTPHDLIFPHKPGIIMIPEDAKRGTELDYVIARKNPLFQKPVYLELWGSPLFAIRQKIVSSETTEGTVFLLGPLDFEKQAMYHLTILANDAYAEPGQDSRNIAGMEIVVIVQDVQDQPPVFTSAPPVTKLPPGILPGDKILQVHAEDGDKGNPREVRYGLVSENNPFTSFFDINETSGEIFLMRPLEDIAFITHVGDPVLLTVIAEEVKVGRDEPPALASTVQLAFFLPDRTNSPPYFENDHYVSRVDENAPQGTALTFVDPYVPRVYDDDTGKNGVFSLTLLNNNGTFEISPNVAERSAGFLIRVRDNSMLDYEQQQSVQFQILAQELGPATNLSALVNVTVYINDVNDNAPVFEQPAYSVELPENMTAGTKVVQVLATDPDSGLGGKVRYTAILGYLNTSLNLDAETGLITVSTNKHGFDREVMPEYHLYVEARDMDGEGNRAQVPLIIKLIDVNDETPIFDKDLYEFILTHDLMGFTTTAVIHAEDKDATAPNNEVRYEIINGNYDNQFVLDKVTGELTVREKIHLRSKKNAKTRRRRQAGSDDEDTDIFILTARAYDLGVPVRFSTTTIRVYPPESRKRSVKFVVPGHNPDKAKTEETLSALSGGKVYIHNIRPLSPDEPGAKDIPAGNPGIKERSVVTATVIYDSSSVVDISEIQQRLSHHNNSYAIMPQDTSSTDTQYKAENKVLFWLLILLATLVALTILILLLCCICSWCPLYGAATKRIVNISRTEDDVHLVHREMANGKQTKSVQVAEWMGRRDAWSAEKPPDTRTKPTRWEFHDGREQLDEDVGRGQDIGEGDRRHIQSAEEQQRRVRIKHNRTAKDDLHLNFHNSRTNLINDRDVYMEDVIENRDLAGDREHITRTRVNRQEYARRKQYDSEVRHIDDDSMRRHEIDRGSDIDFNTAHNSLKSKRELFIKDGNVEILQLMTRDKTRDGLNLDDDNIYVNVPLKPAGNLSHPQLLMVDNTGKEILMRRFIEEQPDGKQIIREHYQIVPGATYIQSMPNEVQQGSTLKGDTFPLGKSGPNSIVYSQLEPEVKVIHTQPVQAGEGVSLDQQMQPAVSNQSLTHELEHSLKQQNALLRQILMEKEKLENAYTQHEVALETQSLPGQSMAIGTQTDCDAGTQTEGFDGVLDPEISLAKPSRRRARSENDESMSEDGYEYVRFNPPNSPEGVYWIKRRRTKKRPRQPRKRIVMVEEVKRKIRTPIKEEEEVQERKKRVPPKKPLRETKTSILRKQLSDESRKDQSRNGESQTGNRHRSESDSHNRDMFMEITDSMDELASPGSHSIRKIQVEKYYKHSDGDFDEDDTEYSIDSDGDEIVIRTNYPSRAQENERYRRQERTYAEPENPVDRKRPARKSSPTDSQPEAMPRLSRRDSSKRGSRKQTSSEPPHNRVSISKYESTVTENGRKLMSTSTEIVGSKRSLTDRSYQSETELAGLEHEERNVPKYMEWYYNKKKSSVSGRTSTESSKSQPSSKKKVGAAEKRVSKTRITAQPKDVEEYDETGGRYKPEPAPRKSPPKGSRLLKEDRALNKQHKPKIETDTNHPLLQHSEHRFERENALEVPAAPTKLPHYMYPETPPHAAAGGKESKSGRESKTSKEAKPKPSPIRENEVKVSNSKIYVEHRGTGHPTQKQLNASTLEDDHDSGIAMNSLLNSLGRRNPIAEKKSVFSIAYDDVSRVKKINSGGESPQYS
Protein: Probable nitrate reductase molybdenum cofactor assembly chaperone NarW (Redox enzyme maturation protein NarW) (P19317)
Organism: Escherichia coli (strain K12)
Function: Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Respiratory nitrate reductase 2 alpha chain
- Respiratory nitrate reductase 2 beta chain
- Respiratory nitrate reductase 1 alpha chain
- Respiratory nitrate reductase 2 gamma chain
- Respiratory nitrate reductase 1 beta chain
- Nitrate/nitrite transporter NarU
- Respiratory nitrate reductase 1 gamma chain
- Nitrate reductase molybdenum cofactor assembly chaperone NarJ
- Nitrate/nitrite antiporter NarK
- Chaperone protein YcdY
Sequence:
MQILKVIGLLMEYPDELLWECKEDALALIRRDAPMLTDFTHNLLNAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRELPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGSSLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDVAPQYVDISAGGGK
Protein: Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (p14) (P53999)
Organism: Homo sapiens (Human)
Function: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
Subcellular location: Nucleus.
Interaction partners:
- Symplekin
- Transcription initiation factor IIB
- Cleavage stimulation factor subunit 2
- Small acidic protein
- TATA-box-binding protein
- DNA topoisomerase 1
- Transcription elongation factor SPT5
Sequence:
MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
Protein: Adenosine receptor, isoform A (Q9VAA2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Adenosine deaminase
- Equilibrative nucleoside transporter 2, isoform A
- G protein beta subunit 5
- Guanine nucleotide-binding protein subunit beta-1
Sequence:
MSAFRYFSITDFSFEGPLLPLHAATTSKDAKDSDSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRSTQPRLYVGEYSPIWLRQQQEALKNSQLLPKCGVVSPCFNNINQTVAAVASVTTDLEREMWNIVEASSGAELGETSYEFPSPAPGSQRSSERNSSSTVPPAPPAPAKPSVPSASYDNHNYSFSQDEDEDDDDLEFEDVFVPASSVPNPVQPGIDPVELRRSLALVMREKLRSDDTDSRPMGNNQDLPIDEQSRERPLSTQTSPTNGPLPALLRAKLLAGNSNSAHCLPGSTASPAPQEQSGIFVIDSEASPGSNGHKPKYRKGTAFTRSSLKKSRSCNCSSIAKGRGVHDEPSSNLCRDQESSVLPQHPQPANHPTENFFSPLRSVGSFMQHSNLFHFLQPHAARPTSSTASSTASTPTPSPPPMGQAQEESVPVGLTTSSPSLLATSAES