wanglab/gogpt-training-data huggingface dataset:
Protein: Aspartyl-tRNA synthetase, mitochondrial, isoform A (EC 6.1.1.12) (Aspartyl-tRNA synthetase, mitochondrial, isoform B) (SD02215p) (Q9VJH2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Glutamyl-tRNA
- Bifunctional glutamate/proline--tRNA ligase
- Aspartate--tRNA ligase, cytoplasmic
- histidine--tRNA ligase
- non-specific serine/threonine protein kinase
- Tyrosine--tRNA ligase
- CTP synthase
- Valine--tRNA ligase
- valine--tRNA ligase
- Probable proline--tRNA ligase, mitochondrial
Sequence:
MSGRYRGGGGGRFGGRGGGGYADGGGYNDFDNYRGGGGPGFNDNFGPGPGPNPFNMGGPNISGNELMQLMSAMASNFNMNSQPPQPMRQSCGELRNHHCGLFVELSGRLIKKRVNRFAELRDRNGGACQLVVLEDKHPRVARRMNNMPENTTLTIVGLVMRRPHNSCNQTMPTGEIEVEVQDILNIHFPAGGTKRAGDKRTYSTMVQQQSNLGITSTEYKIAKNENILKYFENRDLTCNDLRRDDVGKTVTLVGWIPSTKNNKFLQLKDGYGQTQLMIEDQSLSDTFLSTPEQTVIQIVGKVLGRPKANVNLKYDTGEVEVSVTSVKVLNPDDPYDGPIKAKEKKQKFSIDDLEAEEAAAEASANLTSNNGESTEDSAEASTTANASLIAEQRAKVADTNKFADRTHNCGELTSNDINEKVVICGWLEFQRMNKFFILRDAYGQTQVLLSPKTYGLEEYAETGVPIESIVRVEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLPFEIRKFNRAGERLRLTHRYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRRTPGGAQEFVVPTRKAGHFYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQPEFTQLDIELSFTSRDDIMQLIEETLRYSWPKDFPRLQTPFRRITYEEAMEKYGNDKPDTRFGFLLNNVSEIIEKSDEFKEKYDDLGAYAIVVRASEAFWNGAARKHYESLGKEFKGTLFVRKFGPTKDVQEKLGKLLGEDVATEVADKFDLEENDLLFLGIGSKVETRELLGRIRLDYQDFLVENAKIKKPNDFRFLWVIDFPLFERNRETNQLESVHHPFTLPHSDDLENFATSCENLESIRSQAYDLVLNGQEVGGGSIRIHDRDMQHFILEQILKIPHDHLSHLLSALESGCPPHGGIALGLDRLIAILCRARSIRDVIAFPKSLNGRDPLSNAPVPISDEEMRLYHLSVVDEEEPSTNNTSHEQEDDDPDQERAPPSPMSATSESEQPQINVDIKQEPEGLNEDFAPESPATKSTVKADPDEPSPSNPLASEAATPARARRTVKKKV
Protein: ATP-binding cassette sub-family B member 5 (ABCB5 P-gp) (P-glycoprotein ABCB5) (EC 7.6.2.2) (B5X0E4)
Organism: Mus musculus (Mouse)
Function: Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells (By similarity). Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25030174}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:25030174}.
Interaction partners:
Sequence:
MANSERTNGLQETNQRYGPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLINGCLVQTNRTKYQNCSQTQEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAKQGLYYSLAMAQDIKKVDEQMESRTCSTAGNASYGSLCDVNSAKAPCTDQLEEAVHHQKTSLPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVTMFEDKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKPTINSCSQSGEKPDTCEGNLEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQVLLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDKARRGKTCLVVAHRLSTIQNADMIVVLQNGSIKEQGTHQELLRNGDTYFKLVAAH
Protein: Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase) (Q7Z3E1)
Organism: Homo sapiens (Human)
Function: ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR.
Subcellular location: Nucleus {ECO:0000269|PubMed:23275542, ECO:0000269|PubMed:30373764}.
Interaction partners:
- Poly [ADP-ribose] polymerase 1
- Protein mono-ADP-ribosyltransferase PARP16
Sequence:
MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
Protein: Alpha-galactosidase (EC 3.2.1.-) (D3ZJF9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Lysosome {ECO:0000256|ARBA:ARBA00004371}.
Interaction partners:
- Beta-galactosidase
- Glucosidase, alpha; neutral C
- Lactosylceramide 4-alpha-galactosyltransferase
- Arylsulfatase A
- Beta-hexosaminidase subunit alpha
- Galactocerebrosidase
- Lysosomal alpha-glucosidase
- 2-hydroxyacylsphingosine 1-beta-galactosyltransferase
- Lactase/phlorizin hydrolase
- Sialidase-3
Sequence:
MAMKLLSGDTPLVCELALRPLALVFWSILGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDACISEQLFMQMAELMVSDGWRDAGYEYLCIDDCWMAPERDSKGRLQADPKRFPSGIKHLANYVHSKGLKLGIYADVGKKTCAGFPGSFGSYDIDAQTFADWGIDLLKFDGCHCDSVVSLANGYKYMSLALNRTGRSIVYSCEWPLYLRPFHKPNYTDIQYYCNHWRNFDDVYDSWESIKSILAWTVTHQKDIVEVAGPGGWNDPDMLVIGNFGLSWDQQVTQMALWAIMAAPLLMSNDLRQISSQAKALLQNEDVIAINQDPLGKQGYCFRKENEIEVWERPLSNLAWAVAVRNLQEIGGPRFYTIQISSLGRGLACNPGCIITQILPEKVHLGFYEWPLTLKTRINPSGTVLLRLER
Protein: Glycerol-3-phosphate acyltransferase 4 (GPAT4) (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta) (Testis spermatogenesis apoptosis-related protein 7) (Q8K2C8)
Organism: Mus musculus (Mouse)
Function: Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone. Active against both saturated and unsaturated long-chain fatty acyl-CoAs (By similarity). Protects cells against lipotoxicity (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q86UL3}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glycerol-3-phosphate acyltransferase 1, mitochondrial
- Glycerol-3-phosphate acyltransferase 2, mitochondrial
- 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
- 1-acyl-sn-glycerol-3-phosphate acyltransferase beta
- Glycerol kinase
- Glycerol kinase 2
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- glycerol kinase
- Glycerol-3-phosphate dehydrogenase 1-like protein
Sequence:
MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKTLLKIFAWATLRMERGAKERNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDKTPEFELSDIFYFCRKGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTILWGLGVLIRYCFLLPLRIALAFTGIGLLVVGTTMVGYLPNGRFKEFLSKHVHLMCYRICVRALTAIITYHNRKNRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREKDEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDTFKEEQQKLYSKMIVGNHEDRSRS
Protein: GDP-L-fucose synthase (EC 1.1.1.271) (Q382D8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- GDP-mannose 4,6-dehydratase
- Glucosamine 6-phosphate N-acetyltransferase
- 40S ribosomal protein S23, putative
- 40S ribosomal protein S15, putative
- 40S ribosomal protein S8
- 40S ribosomal protein S4
- 40S ribosomal protein S15a, putative
- 40S ribosomal protein S25
- Small ribosomal subunit protein uS5
- 40S ribosomal protein S33, putative
Sequence:
MLSFDFFFFLLLLSCLYSIRDTLHRFVEGSPCRVVGQKTMLGSLPSVVLVTGGAGLVGRAVEVVTKRNACADERWVFLSRHDADLRSMAATRCVFERHKPTHVLHLAARVGGLFKNMAAPVEMWIDNVSINNNVLECCRTYGVRKAVSCLSTCIFPERATYPIGEETLHDGPPHYSNEQYAYAKRMIDVLNRAYNKEYGCRFTSVIPTNVYGPHDNYNLQDSHVIPGLIHKFYLAKRENKPMVIMGTGRPLRQFVYSEDLAELIVWVLRHYDEVEPIILSVDECDELCIADVAKLIAQSIGFTGNIVFDPSKADGQYRKTADNAKLRRYLPDYRFTPVAEGIQRSVEWFIANYDVARK
Protein: Muscleblind like splicing regulator 1 (H7C4Y1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
QQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMALANMQLQQHTAFLPPGSILCMTPATSVDTHNICRTSD
Protein: Geranial dehydrogenase (GaDH) (EC 1.2.1.86) (Geraniol oxidation pathway protein B) (Perillyl aldehyde dehydrogenase) (H1ZV37)
Organism: Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen) (Alcaligenes defragrans)
Function: Catalyzes the NAD(+)-dependent oxidation of geranial to geranic acid. Is involved in the anaerobic degradation of the monoterpene beta-myrcene. Seems to be specific for the trans-isomer geranial, since it does not act on the cis-isomer neral.
Interaction partners:
Sequence:
MTIDHQHIFVGGQWIAPKSTQRSNILNASTEELVGSVPKCNNEDMDRAVAAAREAMRSLAWAGLDGKGRAQHLRRFADAVERRGQQLARSVSLQNGMPINVADQLESAFVVSLLRYYASLAENLVEEEARPSPTGSTTLVRRDPVGVVGAIIPWNFPVALSIFKIAPALAAGCAVVVKPSSGTVLDSYVLAEAAAEAGLPPGVINWVPGDRGIGSHLVSHPGVDKVAFTGSTSAGRIIAEACARLLRPVTLELGGKSAAIVLEDADLDALIRSLPMSSVLNNGQACFSCTRILAPAGRYDEVVDAIAGAVSAYSVGDALDRATVVGPMASAAHRDSVQRYIELGTGEARLVVGGGRTSQDRGWFVQPTVFADVDNRSRIAREEIFGPVLSIIRYEGEDEAVEIANDSEYGLGGTVWSTDHDHAVTIARRMETGTVGINGYMPDLNAPFGGVKSSGMGRELGPESIGAYQRYKSVYLLG
Protein: Uncharacterized protein (Q38AD8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRQSSLPEEDAFLCLLKQIEREGYTPNIGERAVICRTINGVFNPLGVYFALIGASCGYFGLGMAVRASQRLASSVVGFLYMAELSWSFQERRPCAGFLNDVRSLDGQLREKTGSQHLLGEFSLMDRSLIGEIFDFVTLDKTIRWLLCLTSSCASGPHWLPFVKIKWFDGLPLDPLTIWYWRFVLSFYR
Protein: Kazal type serine protease inhibitor 4 (Q6IE48)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MAMHLWLVTLTLVPLLAMDRFPQPICEHMAEFPNCPRSPNLICGTDGLTYENECHLCVTRMKTKKDIQIMKDGKC
Protein: ZZ-type domain-containing protein (F1LIM5)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSKIRITTFSRTPQLFVRLETVPLRPTALPSVSTETAKKASDADRESKSRSSLKRIENNQELTLKTLEKLQKELSRVSALETMVADLHAKEREPVVEEVQKPFPPVKHSASCDACLGDIIGHRFKCLECADYDLCEKCERKSLHYEHAMIRIVEPKKTMIPSYVTSNSPNNVFPTYMQHKIQQPQTIKGINKTVITRLVPSHQVNPAPMPQAPPVSTPVPFPPSPTIGNGAVPKPAQEPRIPPSPTSALPPPQFFNEETRAAIINSAALLKETFSTLSRSFLDLADGAQANMDKKIIERSTMEAGMTKFEEKMDNLKRHCEEKYLGTETAEAEKSEESSKKQADSLSGPKIKKAKKKSCYKKSAERLFTMQLAAAAAEQARLEQEAKKRAEASSAELQRKLAELNVKESQSKSEENIADFVLYDLYGNSLEALLRGRSSSRIADPPTTPNTEPATTELASTTSATPAVTAPASIVPVTPTAPIVETLIVPPLPPVESNPEEVTPMVTAPISIHSSFENISSDFESLSPSWGGYPDLEAAQRLEVIDDNLLDFSDVAVEAQEAQEAQEEARPEPEQSLPPFNEETEKTFDRLLEMGFSYNVTVAAIRANGSNLEMCLQALLH
Protein: phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (A0A8I5ZVZ5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MIATGWLPPCFDFYRLSWHRLRPWCRSPCRSIQTLRVLSGDLSQLPAGVRDFVERSAHLCQPAGIHICDGTEAENAATLALLEEQGLIRKLPKYENCWLARTDPKDVARVESKTVIVTSSQRDTVPLLAGGASGQLGNWMSPDEFQRAVDQRFPGCMQGRTMYVLPFSMGPLGSPLSRIGVQLTDSPYVVASMRIMTRLGTHVLQALGDGDFIKCLHSVGQPLTGHGDPVGRWPCNPEKTLIGHVPEQREIVSFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITNPAGKKRYVAAAFPSACGKTNLAMMRPALPEKKKKKIEEDFLQPHSLAFPSCNTVFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCVPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFSWRHGVFVGSAMRSESTAAAEHKGKTIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGARLPRIFHVNWFRRDEAGRFLWPGFGENARVLDWICRRLGGEDSARETPIGLVPKEGALDLSGLRAIDTSQLFSIPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALEERVQKM
Protein: Hypoxanthine DNA glycosylase (HDG) (EC 3.2.2.-) (Q46EH7)
Organism: Methanosarcina barkeri (strain Fusaro / DSM 804)
Function: Excises hypoxanthine, a deamination product of adenine, from double-stranded DNA. Acts on double-stranded DNA containing G/I, T/I, A/I and C/I base pairs, but not on single-stranded inosine-containing DNA. Has also minor xanthine DNA glycosylase activity. Lacks any detectable uracil-DNA glycosylase activity.
Interaction partners:
- DNA-
Sequence:
MKKQGFPPVIDENTEILILGSLPGDVSIRKHQYYGHPGNDFWRLLGSIIGEDLQSINYQNRLEALKRNKIGLWDVFKAGKREGNEDTKIKDEEINQFSILKDMAPNLKLVLFNGKKSGEYEPILRAMGYETKILLSSSGANRRSLKSRKSGWAEAFKR
Protein: Beta-toxin Cl13 (CliNaTxBet37) (C0HK69)
Organism: Centruroides limpidus (Mexican scorpion)
Function: Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity). Inhibits sodium channels Nav1.4/SCN4A, Nav1.5/SCN5A and Nav1.6/SCN8A. Also has a weak inhibitory effect on Nav1.2/SCN2A. Is lethal to mice.
Subcellular location: Secreted {ECO:0000269|PubMed:27871874}.
Interaction partners:
Sequence:
KEGYLVDYHTGCKYTCAKLGDNDYCVRECRLRYYQSAHGYCYAFACWCTHLYEQAVVWPLPNKRCKGK
Protein: Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2) (Q9HCS7)
Organism: Homo sapiens (Human)
Function: Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:25599396, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770}. Note=Detected in the splicing complex carrying pre-mRNA. {ECO:0000250|UniProtKB:Q99PK0}.
Interaction partners:
- Pre-mRNA-splicing factor RBM22
- Cell division cycle 5-like protein
- Splicing factor YJU2
- Peptidyl-prolyl cis-trans isomerase E
- RNA helicase aquarius
- Protein BUD31 homolog
- Pre-mRNA-splicing factor SYF2
- Pre-mRNA-splicing factor SPF27
- Pre-mRNA-splicing factor ISY1 homolog
- SNW domain-containing protein 1
Sequence:
MVVMARLSRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPLRAQSKILFVRSDASREELAELAQQVNPEEIQLGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED
Protein: Uncharacterized protein YLR287C (Q05881)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- MIOREX complex component 12
- Protein HGH1
- Translation machinery-associated protein 16
- Regulator of rDNA transcription protein 14
- L-2-aminoadipate reductase
- 25S rRNA
- Uncharacterized protein SLP1
Sequence:
MSTGSSDRKDDVKLLELLNSIDEQFLVPYKKPEDLRKISSTTKLQGSTPTKELDKLASVLKAHCTKIGIVCKPGTFDNNHKVVITEIQNFSRPLFYLLSLFPLFYNNKDCPKYFTDQLDESTLQLLDGLRDFIAELQERLKNDENASLDKERLTSVGKIFNACDSLSNCSKAGPYGILANILKDNVAIMDDTMNEIKEWLEEPDFSANSDDIFLDFEDSESESDSQKEEFDQEKVYENIKLFFDGFTRKIKLIKLLVSTFRKTLVSKDFTPKRNQAETLDSIHTYLKEIQLLLDEVVSTVQFEPKNFTNEEVKEEQAALVAVTKKVLIQMSKLYEGDPKRKKWIDTWEIKFNELF
Protein: Agrin (G5EG68)
Organism: Caenorhabditis elegans
Interaction partners:
- Dystroglycan 1
- 43 kDa receptor-associated protein of the synapse homolog
- Fibronectin type-III domain-containing protein
- Probable syndecan
- GlyPicaN
- Low-density lipoprotein receptor-related protein
- B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog
- B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog
- Nidogen
- EGF-like domain-containing protein
Sequence:
MRLHNYFVSIFLFSCIVWTVFSSCLKPRPTRSYIHSLFENSDVIIAGVITGISYRVDSLYIENITVIPRRIYKGREYVEENKNIVIGNILETEPCAHRLLASDVRIFSLTNQQGVFLLDAPMIRVSLPIFDALFTISNKQAHRKRRRTKQAICEQSLCPFGSKCGLKTGVCECKARCRVVTDVVCGSDHVSYSSFCHLSVRSCVLAKNGVRLRVATKGPCKKRNPCEDLRCGPGEDCVVNQINGILLAKCVCPTQCPNYGDSVESSPVCSSHGVDYQSSCHLRHHACESKTNITVKFFGRCDPCHGHKCPNGQTCQLGVDRRPECKCSEQCTMNSAHVCGTDGKTYLNECFLKLAACKEQKDILVWKRGNCDEAGSPCEKMECGFWGSCVVKPDRTAECECPNRCEDVMRPVCATNGETFDNECEMKKKSCETKSMIKVKHQGTCGIGVCATFDSCKKPQVCVVVDGKPKCVCPSCTDEFKEVCGSDGKTYSNECRLQNAACMAQKNIFVKYNSACEACKLKKEKCDFYSACVVGENEKAECKCPDDCPSYEMEEGKEVCGTDGVTYSSECHMKKSACHQSKFVMTAFEGKCDECLHVQCRYGEECRSGVCVCSYNCPANPPLSARICGENGVLYPSLCHLQLASCQKGAPISEMPPSHCHSSKTSFPDSCQCNRVGSFGHTCDETGQCKCRPGVAGIKCDHCLPSFWGIHLIAQGALSCRPCGCSAFGSSRSDCEQTTGKCECKNGALGDKCDLCPNGSMMTAGGCVSPAVYKTPRDCHSLRCFHGAKCVPSPSSFPDCICPQSCNMNHLGIVANMTVCGSDGTTYSNLCELKMFACKHQIDVVPVSMGICDDENFEVLDRLQREKNSNEKRLGSPCTRHEECEKLSAQCITRPGRKSVCDCDDGWKSHLGICIEISKKRKSDQLELTTDINSDWYFSRKDINRFSKLSMHIHLKEKREGILIRMVTEDKKDLQISHENRRIVIKVGKARVDSLQTIAYNVSLELKWKRNEVHFKLNGEVQKYTFEDVLDSSVKRIYVGTDGKWPRNRLNSIVGYLEIDDEPVRIDEIKPFYMAPEISRTLKFKENGFVQFENLQIDVRERTRVEIVFKPYRTNGILFYWSVPSDPHTDFIAFAMIDAKPHFVYELGSGLSYIRGEPIPLNSWHTVRIERLAKDVSMFVNETLVKKHTSQSKNAHLDISKKDALYVGFVPEGIISHKVRKLNVPFEGELQELRINELPINLISGVSKEVMDKVDVMEINEKEISKCDGASFDRKGSVVCRQHENDARGIHINEQDALVFPNNVTFSVGSSKSSNFSFDFRTLKQFGVIWQEGAWSQADEGGDFLLVFIEEGKLYVGVNLGADVHLKPISTNVTVADNHWHSVSFRRKERKCELWVDSKKILHVVASPGDVNLDSNGLVYLGGANPKKHKLLKSLNLSNKFVGCVKNLKIFGAEVNLLVDSLKSIETPKYCYN
Protein: Homeobox protein Hox-C4 (Homeobox protein R3) (P18865)
Organism: Rattus norvegicus (Rat)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeo box C5
- Homeo box C6
- Homeo box B5
- Homeo box B6
- Homeobox protein Hox-D4
- Homeobox protein
- Homeobox protein Hox-B7
Sequence:
LVVMLESRFPGPARGVANCRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHDSPTPK
Protein: RAR-related orphan receptor C (A0A0G2QC01)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
- Forkhead box P3
- Nuclear receptor corepressor 2
- Nuclear receptor ROR-beta
- RAR-related orphan receptor A
- Nuclear receptor coactivator
- Nuclear receptor coactivator 2
- Interleukin-17A
- Nuclear receptor interacting protein 1
- Interleukin-23 receptor
- Interleukin-17F
Sequence:
MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQQQQREQVAKTPPAGSHGADTLTYTLGVPDGQLPLGASPDLPEASACPPGLLRASGSGPPYSNTLAKTEVQGASCHLEYSPERGKAEGRDSIYSTDGQLTLGRRGLQLGEPEQGSDSHCSPSFCSAPEAPYASLTDIEYLVQNVCKSYRETCQLRLEDLLRQRTNLFSREEVTSYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIILLKAGAMEVVLVRMCRAYNANNHTVFFEGKYGGVELFRALGCSELISSIFDFSHFLSALCFSEDEIALYTALVLINANRPGLQEKRRVEHLQYNLELAFHHHLCKTHRQGLLAKLPPKGKLRSLCSQHVEKLQDFQHLHPIVVQAAFPPLYKELFSTDIESSEGLSK
Protein: T. brucei spp.-specific protein (Q387G8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MELAGDTLLTSLSVSFLFCIPHRDFFCFFFCSTVPTRFTCLPDLVHDLFADAACAIVCTYFHMLLCLKFGVLFFFLLFLFFFGGGGFFFLFLVRGFHRLGSICPSFGGTIGYTLLSLEGGGQYMSRSARLLTVCQKKKEKGNHCAKLQAQDVCG
Protein: Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (FSH-B) (FSH-beta) (Follitropin beta chain) (Q60687)
Organism: Mus musculus (Mouse)
Function: Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (By similarity). Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P01225}. Note=Efficient secretion requires dimerization with CGA. {ECO:0000250|UniProtKB:P01225}.
Interaction partners:
- Follicle-stimulating hormone receptor
- Glycoprotein hormones alpha chain
- Lutropin-choriogonadotropic hormone receptor
- Gonadotropin-releasing hormone receptor
- Thyrotropin receptor
- Progonadoliberin-1
- Pituitary adenylate cyclase-activating polypeptide type I receptor
- Prolactin
- Pro-opiomelanocortin
- Prolactin-5A1
Sequence:
MMKLIQLCILFWCWRAICCHSCELTNITISVEKEECRFCISINTTWCAGYCYTRDLVYKDPARPNTQKVCTFKELVYETVRLPGCARHSDSLYTYPVATECHCGKCDSDSTDCTVRGLGPSYCSFSEMKE
Protein: Protein OBERON 4 (Protein TITANIA 1) (Q84TI3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that functions redundantly with OBE3 in specification of the hypophysis and establishment of the embryonic root. Involved in the activation of ARF5/MP-dependent gene expression during embryonic root meristem initiation. Involved in shoot meristem homeostasis.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9S736}.
Interaction partners:
- Histone acetyltransferase
- Uncharacterized protein At3g24150
- Protein TIFY 8
- Pumilio homolog 5
- Protein TIFY 4B
Sequence:
MKRLRSSDDLDFCNDKNVDGEPPNSDRPASSSHRGFFSGNNRDRGEDAAGFSRAFSRRRSNRDLDNHRPDARYHRSESACFSRRAFPKGFRSERERPNRDASVSSWRRFGGPGNDFGVDDRDRRLRDAERDRSLKSPSWSRDSPNELSKFKPLDSRNSRSRSKSLASPTWSKDSGSEQSKSVGNVVKKSEEEVQGKSSTTSSEMEEGELEPEPQPETASGLAHQTKHDCKLPSCSADDHKNARIDRSFQEIGKSAQLDANTESNRELSHVGGNREMETTDSMTDKKSVEDAENVPEHATESMHVSQNNVNDTSTALAIEHDHRDGTITASANKITDTVDEKGDKDEDYKENLHGVKLEETLYPDVPERLEELKEVKGNDGDANKAEVEGPECVEENALANRTPAEYISSVSDSSVHKCKDKGKNSDVPLTHLVGNALFSESKTEDLHDKDKDEKDDNFGGPSIRGFELFSSSPVRRAKKTEQSGVNKHKDEKLLLEPLDLSLSLPDVLLPIGGQDTNQLGSPVRSGSVRSLTDTFCTNSDGFTMSMSFSGSRSFNHNPSCSLSHNIGDNEQSVHSRPIFQGIDWQALSHNDSKYNENTVYQRLMENGNGSVQPRAMKGNLISGQADEEHLRLPDGSSKAANILEKQLSFQKSVDVRSACPRTGSLENGSKFTVEKKTAKDFYSGSNSWITGLEAGGHDFVETVIRYILSDSMPVMTKRFHEMPTRNITSLKENIRQMMLNMDKNVQLGAFQDALQNRTDITLELLTKSHRAQLEILVALKSGRSDFLLLDNSISSSHLAEIFMNMRCKNLSCRVLLPVDECDCRVCSRKDGFCSACMCLVCSNFDMASNTCSWVGCDVCLHWCHTDCGIKESYIRNGINASGAPGMTEMQFHCVACNHPSEMFGFVKEVFLNFAREWKFERFCKELEYVNKIFSSSKDSRGKQLRQAADAMLASLKSKLIGLPEACNRILGFISDCDSSTPAETSAPFIYEQPKPRHERGSPSQDTAWLRSVCSDNPHNQLKRSASVADAFHRERQVEICAVEMELERGSPKEPRFEELESIVRMKQAEAEMFQGRADDARREAEGLKRIAIAKKEKIEEEYNRRMGKLSMEDAQERRRRRYEELEAMQRGQREFYEMKMRMEEEMRGLLTKMEMTKQSLAL
Protein: LD22310p (Q95RK8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Early endosome {ECO:0000256|ARBA:ARBA00004412}. Golgi apparatus, trans-Golgi network membrane {ECO:0000256|ARBA:ARBA00004150}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004150}.
Interaction partners:
Sequence:
MTTDESIMEEMLERATNPAQKIDELGVQMFCIVAKSNAQLVHKAQEMIVAKVRSTNVTEATRAISLLEECMTQCGDDFQDEASKFRFLNELIRLVSKKYKGAETPHEVKQRIMECLLLWTTEFPQRQKIRDAYDMLRKEGDIEHGTTEAAVAKRESVLGTIDEAMFAKLIKSNNPENFKRANLLLQYRMAQEARRNDLLAQHRLVLCEVQETMQLLNQMLDTYDPANQDVSETLHELYKSCKKHKPIFQHLPQLLDDSDAQLVADTLDANCALLATMQRYKLLVPSPTRSTAAALTTSAPTVASSVKSTASSTTATTSSNNAQLLNELLGDLLIDGSNKAATTATTSLPNAAASGSNPLADLSDIFSSALAESEAKQQSQPFQNATTLLEPQVISQGTTTEALANGNGGSASKVPETIRKMPQIDMLSEELFQQILPTQDRMPSFKRDPEKITLNDLARERMHIKAPEEPTTANDPASDSAPAIATATATVDSIDDVPLLSDDVD
Protein: B-box zinc finger family protein (T13D8.14 protein) (O80748)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Zinc finger protein CONSTANS-LIKE 7
- B-box zinc finger protein 18
- Zinc finger protein CONSTANS-LIKE 6
- Zinc finger protein CONSTANS-LIKE 10
- B-box type zinc finger family protein
- Zinc finger protein CONSTANS-LIKE 3
- B-box zinc finger protein 32
- B-box zinc finger protein 24
- B-box domain protein 30
- B-box zinc finger protein 19
Sequence:
MAQVCHTCRHVTAVIHCVTEALNFCLTCDNLRHHNNIHAEHVRYQLCDNCSMYPSILFCYEDGMVLCQSCYSHHYNCATNGHQTQVVFANMNNQHHDHAHMPHVVHHNNNNNHQQQHVGGHQRRAEMFERSCHGDNNCERWMFAMRCELCVASNSNAVVYCPTHNQILCDSCDRMIHSHEDAVPPHSRCKLCVICKRPSRRFLIGGYQFNFPPVHPPAAEGIPVTPPTELPQQDINYDYLDDVDDFSWFGR
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (A0A090N8Y8)
Organism: Homo sapiens (Human)
Subcellular location: Endosome {ECO:0000256|ARBA:ARBA00004177}. Lysosome {ECO:0000256|ARBA:ARBA00004371}. Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
Sequence:
MGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGARAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRPVGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIYHKGCIDEWFEVNRSCPEHPSD