wanglab/gogpt-training-data huggingface dataset:
Protein: Superoxide dismutase [Cu-Zn] (SOD-1) (EC 1.15.1.1) (P34697)
Organism: Caenorhabditis elegans
Function: Protects cells against oxidative stress by converting superoxide radicals to hydrogen peroxide. Required for normal brood size. May be involved in regulating mpk-1 phosphorylation downstream of phosphatase ptp-2 during oocyte maturation.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Superoxide dismutase 1, mitochondrial
- Superoxide dismutase 2, mitochondrial
- Extracellular superoxide dismutase
- Superoxide dismutase
- Heat shock protein 70
- Peroxisomal catalase 1
- Heat shock protein 90
- Glutathione-independent glyoxalase DJR-1.1
- Glutathione-independent glyoxalase DJR-1.2
- Glutathione peroxidase 1
Sequence:
MFMNLLTQVSNAIFPQVEAAQKMSNRAVAVLRGETVTGTIWITQKSENDQAVIEGEIKGLTPGLHGFHVHQYGDSTNGCISAGPHFNPFGKTHGGPKSEIRHVGDLGNVEAGADGVAKIKLTDTLVTLYGPNTVVGRSMVVHAGQDDLGEGVGDKAEESKKTGNAGARAACGVIALAAPQ
Protein: Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase (Urogen III methylase) (EC 2.1.1.107) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 dehydrogenase (EC 1.3.1.76); Sirohydrochlorin ferrochelatase (EC 4.99.1.4)] (P0AEA8)
Organism: Escherichia coli (strain K12)
Function: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
Interaction partners:
- Porphobilinogen deaminase
- Phosphoadenosine 5'-phosphosulfate reductase
- Sulfite reductase hemoprotein beta-component
- Uroporphyrinogen-III synthase
- Adenylyl-sulfate kinase
- Nitrite transporter NirC
- Nitrite reductase small subunit
- Sulfate adenylyltransferase subunit 2
- Nitrite reductase large subunit
- Uroporphyrinogen decarboxylase
Sequence:
MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
Protein: Secreted protein BARF1 (33 kDa early protein) (p33) (P0C6N0)
Organism: Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4)
Function: Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro (By similarity).
Subcellular location: Secreted. Note=Massively secreted in the serum of EBV-induced nasophyryngeal carcinoma patients. {ECO:0000250}.
Interaction partners:
Sequence:
MARFIAQLLLLASCVAAGQAVTAFLGERVTLTSYWRRVSLGPEIEVSWFKLGPGEEQVLIGRMHHDVIFIEWPFRGFFDIHRSANTFFLVVTAANISHDGNYLCRMKLGETEVTKQEHLSVVKPLTLSVHSERSQFPDFSVLTVTCTVNAFPHPHVQWLMPEGVEPAPTAANGGVMKEKDGSLSVAVDLSLPKPWHLPVTCVGKNDKEEAHGVYVSGYLSQ
Protein: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3) (O70507)
Organism: Mus musculus (Mouse)
Function: Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih) (By similarity). May mediate responses to sour stimuli.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11675786}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Y3Q4}.
Interaction partners:
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
- Sodium channel protein type 2 subunit alpha
- PEX5-related protein
- Sodium channel protein type 5 subunit alpha
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
- Homeobox protein Nkx-2.5
- Gap junction alpha-5 protein
- Short stature homeobox protein 2
- T-box transcription factor TBX18
- Inward rectifier potassium channel 2
Sequence:
MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDGEEEGAGGRQDPSRRSIRLRPLPSPSPSVAAGCSESRGAALGATESEGPGRSAGKSSTNGDCRRFRGSLASLGSRGGGSGGAGGGSSLGHLHDSAEERRLIAAEGDASPGEDRTPPGLATEPERPATAAQPAASPPPQQPPQPASASCEQPSADTAIKVEGGAAASDQILPEAEVRLGQSGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNTEIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLIVETRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVRHDREMAHCAHRVQAAASATPTPTPVIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGPGLGNLGAGQTPRHPRRLQSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPPGLSPLLPSSSSSPPPGACGSPPAPTPSTSTAAAASTTGFGHFHKALGGSLSSSDSPLLTPLQPGARSPQAAQPPPPLPGARGGLGLLEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLAAGPSSTPETPPRPERPSFMAGASGGASPVAFTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESVAAFSLYPRAGGGSGSSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARAASSGGPPLTTAAPQREPGARSEPVRSKLPSNL
Protein: Actin-42A (EC 3.6.4.-) (P02572)
Organism: Drosophila melanogaster (Fruit fly)
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9344535}. Note=Associated with spectrosomes during female cystocyte proliferation and differentiation, but dissociates, or becomes undetectable, upon fusome maturation (PubMed:9344535). Component of the inner rim of ring canals connecting the cytoplasm of nurse cells and oocyte during oogenesis (PubMed:9344535). {ECO:0000269|PubMed:9344535}.
Interaction partners:
- Adenylyl cyclase-associated protein
- Actin-57B
- Actin, indirect flight muscle
- Actin-87E
- ATP-dependent helicase brm
- Brahma associated protein 55kD
- Brahma associated protein 155 kDa
- Brahma-associated protein of 60 kDa
- RuvB-like helicase 1
- Polybromo
Sequence:
MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
Protein: Transcription factor MYB63 (Myb-related protein 63) (AtMYB63) (Q6R0A6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds DNA to the AC cis-elements 5'-ACCTACC-3', 5'-ACCAACC-3' and 5'-ACCTAAC-3' of promoters and specifically activates lignin biosynthetic genes during secondary wall formation mediated by SND1.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:19122102}.
Interaction partners:
- NAC domain-containing protein 12
- NAC domain-containing protein 43
- NAC domain-containing protein 66
- NAC domain-containing protein 73
- NAC domain-containing protein 10
- NAC domain-containing protein 30
- Homeobox protein knotted-1-like 7
- Cellulose synthase A catalytic subunit 7
- Laccase-4
- Laccase-17
Sequence:
MGKGRAPCCDKTKVKRGPWSPEEDIKLISFIQKFGHENWRSLPKQSGLLRCGKSCRLRWINYLRPDLKRGNFTSEEEETIIKLHHNYGNKWSKIASQLPGRTDNEIKNVWHTHLKKRLAQSSGTADEPASPCSSDSVSRGKDDKSSHVEDSLNRETNHRNELSTSMSSGGSNQQDDPKIDELRFEYIEEAYSEFNDIIIQEVDKPDLLEIPFDSDPDIWSFLDTSNSFQQSTANENSSGSRATTEEESDEDEVKKWFKHLESELGLEEDDNQQQYKEEESSSSSLLKNYELMIH
Protein: Toll-like receptor 9 (CD antigen CD289) (Q2EEY0)
Organism: Equus caballus (Horse)
Function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9EQU3}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9EQU3}. Endosome {ECO:0000250|UniProtKB:Q9EQU3}. Lysosome {ECO:0000250|UniProtKB:Q9EQU3}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q9EQU3}. Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:Q9EQU3}. Cell membrane {ECO:0000269|PubMed:19548205}. Cytoplasm {ECO:0000269|PubMed:19548205}. Nucleus {ECO:0000269|PubMed:19548205}. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. Exit from the ER requires UNC93B1. Endolysosomal localization is required for proteolytic cleavage and subsequent activation. Intracellular localization of the active receptor may prevent from responding to self nucleic acid. {ECO:0000250|UniProtKB:Q9EQU3}.
Interaction partners:
- Myeloid differentiation primary response protein MyD88
- Toll like receptor 7
- TIR domain containing adaptor protein
- TIR domain-containing adapter molecule 1
- Toll-like receptor 4
- Toll-like receptor 2
- TIR domain-containing adapter molecule 2
- Protein unc-93 homolog B1
- Toll-like receptor 9
- TNF receptor-associated factor
Sequence:
MGPCHGALQPLSLLVQAAMLAVALAQGTLPPFLPCELQPHGLVNCNWLFLKSVPHFSAAAPRDNVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGITTVPALPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNPCGRALEVAPGALLGLGNLTHLSLKYNNLTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEPVATTGEVDGGKKVWLTSRDLTPGPLDTPSSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSISQAVNGSQFVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGVGHNLSFVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRSLIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSSLTLLPNLETLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTVEPSWFGFLAGSLEVLDVSANPLHCACGAAFVDFLLQVQAAVPGLPSRVKCGSPGQLQGRSIFAQDLRLCLDESLSWDCFGLSLLVVALGLAMPMLHHLCGWDLWYCFHLGLAWLPRRGWQRGADALSYDAFVVFDKAQSAVADWVYNELRVRLEERRGRRALRLCLEERDWLPGKTLFENLWASVYSSRKMLFVLAHTDQVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDARRSRYVRLRQRLCRQSVLFWPHQPSGQRSFWAQLGMALTRDNRHFYNQNFCRGPTMAE
Protein: Collagen alpha-1(XXIII) chain (Q810Y4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000269|PubMed:12644459}; Single-pass type II membrane protein {ECO:0000269|PubMed:12644459}; Extracellular side {ECO:0000269|PubMed:12644459}.
Interaction partners:
- Collagen type XVIII alpha 1 chain
Sequence:
MGAGERAAGGGGTQDPGAGCGARALGALCLLLSVGSATACLLLGAQAAALHGRVAALEQERELLRRAGPSGALAAWAETHLERLLREKLDGVAKLRTVREAPSECICPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGAQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPEGPRGESGQDGEMGPMGPPGPKGEPGTPGKKGDDGIPSQPGLPGPPGPKGEPGDVGPQGETGVDGAPGLKGEPGHPGTDGAIGPRGPPGLKGEQGDTVVIDYDGRILDALKGPPGPQGAPGPPGIPGAKGELGLPGAPGIDGEKGPKGPKGDPGEPGPAGPKGETGEMGLSGLPGADGPKGEKGESASDHLQESLAQIIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPHGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVPGCWHK
Protein: Olfactory receptor family 10 subfamily AK member 7 (A0A1L1SQF6)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MWMIPEQNQSWVSEFILIGFSSDPTTNSILFIVFLLIYLSSVLGNGLIILLVCLDTQLHTPMYFFLCTLSLLDMSYVTTTMPQMLVHLLAHSQTISFAGCWLQMYVFGALGITECTFFVVMAYDRYVAICYPLRYTVILNWGLCIRLAAGSWICGFFSSLLHTFFTMSLPYCGPNRVNHYFCEGPSVRSLACMDTHLIEMVDFVLSVFVVVIPISLIVASYIRIAMAILKIKSTQGRCKAFSTCASHLTVVTFFYAPATYIYLRPNSSYSPERDKQVSLFYNAFTALLNPVVYSLRNKDIKRAFLKVMGHSRLDQ
Protein: Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase (MPE cyclase) (EC 1.21.98.3) (P26168)
Organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Function: Involved in the tetrapyrrole biosynthetic pathways leading to chlorophyll and bacteriochlorophyll (BChl). Catalyzes the anaerobic formation of the isocyclic ring (E-ring) in Mg-protoporphyrin monomethyl ester (MPE) to yield protochlorophyllide a (PChlide a) via a six-electron oxidation and the formation of an oxo group at position C13 using oxygen from a water molecule.
Interaction partners:
- Bacteriochlorophyll synthase 23 kDa chain
- Magnesium protoporphyrin IX methyltransferase
- Bacteriochlorophyll synthase 33 kDa chain
- Geranylgeranyl diphosphate reductase
- 2-vinyl bacteriochlorophyllide hydratase
- Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic
- 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase
- Light-independent protochlorophyllide reductase subunit B
- Light-independent protochlorophyllide reductase subunit N
- DUF465 domain-containing protein
Sequence:
MRILFVHPNYHSGGAEIAGNWPPSWVPYLAGHLKKAGFDDIHFIDAMTLNVSHDELRKKFAELQPDLIGVTSITPSIYEAEETLKIAKEVVPNAVRVLGGVHATFMFRQVLSEAPWVDAIVRGEGEEIMVELAKCVSEGRWPEDRASIKGLAFHDGTEIVATQAAPTVKDIDSLKPDWSLIDWKHYIYIPLGVRVAIPNMARGCPFTCSFCSQWKFWRDYRVRSPKAVVDEIEDLVNNYDVGFFILADEEPTINKKKFVEFCQEMIDRGLNHKVKWGINTRVTDIYRDRDLLKFYREAGLVHISLGTEAAAQLKLDLFNKETTVAENKEAIRLLREADIFTEAQFIVGLDNETKETLEETFQMAWDWQPDLANWSMYTPWPFTPLFQELRDQVEVFDFSKYNFVTPIMKPKALTRGELLDGVMKNYRRFYMRKALFHYPWRGTGFRRRYLLGCLKAFLKAGVGRTFYDLGKAGYWGPQTKDTVDFHFDETRKIAEAQVADWEAAADRSRKHKERQEALRAQMKDRAADRNTANFVMPADAEDEFDLSAETHEARSAEHAAMACGGGKDQMVDAAE
Protein: Packaging protein UL32 (D3XDP0)
Organism: Murid herpesvirus 1 (strain Smith) (MuHV-1) (Mouse cytomegalovirus)
Subcellular location: Host cytoplasm {ECO:0000256|RuleBase:RU364029}. Host nucleus {ECO:0000256|RuleBase:RU364029}.
Interaction partners:
Sequence:
MYRAWDPSLTTIDSFLVNELLLHAHPTKTPPEVTEGQTPSSSSSSSTDSGRETMLEEEEAACCDLDSELARIGDENTAEIRELCLPLEIDSRCNLCAIVSICLRRDPQQKWLLDYCFLCHKCAAAPRTAMATLIVATEFLHLMKLHFRDIAFDNIFKERIVTIFDFHAHFFINRCYTQRDEHPVMVENITLAHMAVTRALLTDDDAVPYTKRRKIQYKLPKKPAPAEPEELRLLDKYRRATEGSFARVLFYIWSGTNVMFNTTLTDLAIKKSKALKALKTRQSEIEPSVGPVFLSPIPTFRLRNATTTVCLLCELMACSYRDNVFLQQLRERITNYSRNNLKIIDRTQLTMAEILSHGRNSEFPQQLKNKDVSIYVTSSPETLAAASRPGTEEPFELSALTYLVLRQVGVIGVYKHLFADPLCAANMRSTDPNILFFDVPNEYLNEAKLAICSTNAYPSRVERDFWLYAHMFKAFQIIKRNFKTKTQLSDFLRDFSQVLESHDFSLVDPSFTVEKYV
Protein: Casein kinase 1 gamma 1 (A0A0U1RR31)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
FFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKYVHLSRGLLSHGLKNLFCLFLSVCCSSQTGFLMLVTTAFFLNCFNFCMVP
Protein: Large ribosomal subunit protein mL65 (39S ribosomal protein S30, mitochondrial) (MRP-S30) (S30mt) (Large ribosomal subunit protein mS30) (Programmed cell death protein 9) (Q9NP92)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11279123, ECO:0000269|PubMed:28892042}.
Interaction partners:
- Large ribosomal subunit protein mL41
- Large ribosomal subunit protein mL37
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein mS27
- Large ribosomal subunit protein mL55
- Small ribosomal subunit protein uS7m
- Large ribosomal subunit protein uL23m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein mS22
- Large ribosomal subunit protein mL66
Sequence:
MAAARCWRPLLRGPRLSLHTAANAAATATETTCQDVAATPVARYPPIVASMTADSKAARLRRIERWQATVHAAESVDEKLRILTKMQFMKYMVYPQTFALNADRWYQYFTKTVFLSGLPPPPAEPEPEPEPEPEPALDLAALRAVACDCLLQEHFYLRRRRRVHRYEESEVISLPFLDQLVSTLVGLLSPHNPALAAAALDYRCPVHFYWVRGEEIIPRGHRRGRIDDLRYQIDDKPNNQIRISKQLAEFVPLDYSVPIEIPTIKCKPDKLPLFKRQYENHIFVGSKTADPCCYGHTQFHLLPDKLRRERLLRQNCADQIEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYFSFFCYQLNTLALTTQADQNNPRKNICWGTQSKPLYETIEDNDVKGFNDDVLLQIVHFLLNRPKEEKSQLLEN
Protein: Iron/ascorbate oxidoreductase family protein, putative (EC 1.2.3.4) (Q57TY7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNHTSIPVIDVSPLFREGEHRVMDVAQQIDWACRTWGFFHVVGHPISPERIGKLMEMAKTFFSLPLEEKLKINIQKSKHHRGYGCLNAENVDPTKPFDCKETFDMGCHLPEDHPDVAAGKPLRGPNNHPTQVGGWMELMETHYRDMRDFALVILRALALAIGLRKDFFDNKFDEPLSVFRMVHYPAQKEGSRHPLVCGEHTDYGIITLLYQDSVGGLQLRNLSDEWVDVEPIEGSFVVNIGDMMNMWSNGRYRSTAHRVRLTTTDRYSMPYFCEPDPYTLIECLDHCHSPSNPPKYPPVRAVDWLLKRFEETYAHRKANM
Protein: DhaL domain-containing protein (A0A0H2UNS2)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNMGMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDELTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAALEGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANMSEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDSLLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKSAEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFLPNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSDVVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEIVTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE
Protein: Transporter (Q9VLY6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Uncharacterized protein
Sequence:
MANNQPPTTNATRKDKRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNSWNTDDCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWVRSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDRAEYEAFRRQRRMPGFMSDTDMESSK
Protein: All-trans-retinol dehydrogenase [NAD(+)] ADH4 (EC 1.1.1.105) (Alcohol dehydrogenase 2) (Alcohol dehydrogenase 4) (Alcohol dehydrogenase class II pi chain) (P08319)
Organism: Homo sapiens (Human)
Function: Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones.
Subcellular location: Cytoplasm.
Interaction partners:
- Aldehyde dehydrogenase, mitochondrial
- Cytochrome P450 2E1
- Aldehyde dehydrogenase 1A1
- Vasopressin-neurophysin 2-copeptin
- Aldehyde oxidase
- Cytochrome P450 26A1
- Amine oxidase [flavin-containing] A
- All-trans-retinol 13,14-reductase
- Amine oxidase [flavin-containing] B
- Lecithin retinol acyltransferase
Sequence:
MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF
Protein: AT5g11720/T22P22_110 (Alpha-glucosidase 1) (Glycosyl hydrolases family 31 protein) (Q9LYF8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable alpha-amylase 2
- Alpha-amylase 3, chloroplastic
- Alpha-amylase 1
- 4-alpha-glucanotransferase DPE2
- 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic
- Acid beta-fructofuranosidase 4, vacuolar
- Alpha-galactosidase 3
- Beta-fructofuranosidase, insoluble isoenzyme CWINV6
- Beta-fructofuranosidase, insoluble isoenzyme CWINV1
- Beta-fructofuranosidase, insoluble isoenzyme CWINV5
Sequence:
MSSLHWFPNIFIVVVVFFSLRSSQVVLEEEESTVVGYGYVVRSVGVDSNRQVLTAKLDLIKPSSVYAPDIKSLNLHVSLETSERLRIRITDSSQQRWEIPETVIPRAGNHSPRRFSTEEDGGNSPENNFLADPSSDLVFTLHNTTPFGFSVSRRSSGDILFDTSPDSSDSNTYFIFKDQFLQLSSALPENRSNLYGIGEHTKRSFRLIPGETMTLWNADIGSENPDVNLYGSHPFYMDVRGSKGNEEAGTTHGVLLLNSNGMDVKYEGHRITYNVIGGVIDLYVFAGPSPEMVMNQYTELIGRPAPMPYWSFGFHQCRYGYKNVSDLEYVVDGYAKAGIPLEVMWTDIDYMDGYKDFTLDPVNFPEDKMQSFVDTLHKNGQKYVLILDPGIGVDSSYGTYNRGMEADVFIKRNGEPYLGEVWPGKVYFPDFLNPAAATFWSNEIKMFQEILPLDGLWIDMNELSNFITSPLSSGSSLDDPPYKINNSGDKRPINNKTVPATSIHFGNISEYDAHNLYGLLEAKATHQAVVDITGKRPFILSRSTFVSSGKYTAHWTGDNAAKWEDLAYSIPGILNFGLFGIPMVGADICGFSHDTTEELCRRWIQLGAFYPFARDHSSLGTARQELYLWDSVASSARKVLGLRMRLLPHLYTLMYEAHVSGNPIARPLFFSFPQDTKTYEIDSQFLIGKSIMVSPALKQGAVAVDAYFPAGNWFDLFNYSFAVGGDSGKHVRLDTPADHVNVHVREGSIVAMQGEALTTRDARKTPYQLLVVASRLENISGELFLDDGENLRMGAGGGNRDWTLVKFRCYVTGKSVVLRSEVVNPEYASKMKWSIGKVTFVGFENVENVKTYEVRTSERLRSPRISLIKTVSDNDDPRFLSVEVSKLSLLVGKKFEMRLRLT
Protein: Reticulon-like protein (Q585Y2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363132}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363132}.
Interaction partners:
- Vta1/callose synthase N-terminal domain-containing protein
Sequence:
MSCFLCNQLKGLTPWEVLSWHRPTATGSLFAVLLSTILFFWYMKYTVVTFLCRLLQVLFAAMPLMGFMKWGTYTNDDIQMMVDRFADCFAPYAVLVLQKIYDLVTWRDRKQSGAIAALTVVLAIVGNYFSDMAVLGLIVTLLFTAPVVYEKNKEVIDNATADIMAMAEEHLGALRTKVDQLTKKNN
Protein: C-type lectin domain family 17, member A (Prolectin) (Q6ZS10)
Organism: Homo sapiens (Human)
Function: Cell surface receptor which may be involved in carbohydrate-mediated communication between cells in the germinal center. Binds glycans with terminal alpha-linked mannose or fucose residues.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=In fibroblasts, expressed on the cell surface. {ECO:0000269|PubMed:19419970}.
Interaction partners:
Sequence:
MHNLYSITGYPDPPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGSSAPPRPPRAAKETEKPPLPCKPRNMTGLDLAAVTCPPPQLAVNLEPSPLQPSLAATPVPWLNQRSGGPGCCQKRWMVYLCLLVVTSLFLGCLGLTVTLIKYQELMEELRMLSFQQMTWRTNMTGMAGLAGLKHDIARVRADTNQSLVELWGLLDCRRITCPEGWLPFEGKCYYFSPSTKSWDEARMFCQENYSHLVIINSFAEHNFVAKAHGSPRVYWLGLNDRAQEGDWRWLDGSPVTLSFWEPEEPNNIHDEDCATMNKGGTWNDLSCYKTTYWICERKCSC
Protein: Cdc42 guanine nucleotide exchange factor 9 (A0A5F9ZGZ3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MHSYNIVKNKVIISWHQQATPGMWATVTSATGEWGMLWVNQEDEVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNSARSVPPSYPPPQDPLNHGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK