wanglab/gogpt-training-data huggingface dataset:
Protein: 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) (Q99460)
Organism: Homo sapiens (Human)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Interaction partners:
- Proteasome subunit alpha type-1
- Proteasomal ubiquitin receptor ADRM1
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 4
- Proteasome subunit alpha type-2
- Ubiquitin carboxyl-terminal hydrolase 14
- 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome regulatory subunit 8
- 26S proteasome regulatory subunit 6B
Sequence:
MITSAAGIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKDSDSMETEEKTSSAFVGKTPEASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPETCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD
Protein: Visual system homeobox 2 (Ceh-10 homeodomain-containing homolog) (Homeobox protein ALX) (Homeobox protein CHX10) (Transcription factor VSX2) (O42477)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q61412}.
Interaction partners:
- Transcription factor atoh7
- POU domain protein
- Six3
- Sine oculis homeobox homolog 3a.
- POU domain protein.
- Insulin gene enhancer protein isl-1
- Forkhead box protein N4
- Calbindin
- Recoverin b
- Recoverin
Sequence:
MTGKDGAVLSESLNKSKSLCATENGGNNNPHLSKSSITHPPKCTGFGIQEILGLNKEPSSAPRSTLDSFPAGAHLLASRSMLGPAGVGVGVGMGLIGPGGIPSFYSQPAFLEVLSDAQNVHLQPLSRTVGPLEHNQSASSDSDDVSSSERKMSKSSLSQSKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPVQDGFPTTSCFSKHEYPPFFAESILKSAKDGIMDSCAPWLLGMHKKSLETAGHQSNEKSDVTQTPTNPKPDEAEAEERRTESPMSKEELRENSIAALRAKAQEHSAKVLGTVSSERLEHNMETTATEEKSSEQIDAKEEEKSS
Protein: Lysine acetyltransferase 5 (E9PRL6)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRARRRYFDEGAWLLAAPRALAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKC
Protein: Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta-like protein (P0C2Y3)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Plastid, chloroplast stroma {ECO:0000305}.
Interaction partners:
- Methylcrotonoyl-CoA carboxylase subunit alpha
- 4-hydroxyphenylpyruvate dioxygenase
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Ribulose bisphosphate carboxylase small subunit, chloroplastic
- 3-methyl-2-oxobutanoate dehydrogenase
- beta-ketoacyl-[acyl-carrier-protein] synthase III
- Uncharacterized protein
- acetyl-CoA C-acyltransferase
- Uncharacterized protein
- acetyl-CoA C-acyltransferase
Sequence:
MALQSLRGSMRSVVGKRICPLIEYAIFPPLPRIIVYASRRARMQRGNYSLIKKPKKVSTLRQYQSTKSPMYQSLQRICGVREWLNKYCMWKEVDEKDFGFEIGAFD
Protein: tRNA-dihydrouridine(20) synthase [NAD(P)+] (EC 1.3.1.91) (mRNA-dihydrouridine synthase DUS2) (EC 1.3.1.-) (tRNA-dihydrouridine synthase 2) (P53720)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U20 in cytoplasmic tRNAs. Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- tRNA
- tRNA acetyltransferase TAN1
- tRNA
- tRNA
- tRNA
- tRNA dimethylallyltransferase
- Multisubstrate pseudouridine synthase 7
- tRNA
- tRNA
- Multisite-specific tRNA:
Sequence:
MVTYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCVRKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDGPSWVVACREFIQWATKFDNHIGNTKYMLSRIVPGKSVFFQYFARCKSPEEVSFVLKQLNDDGSAQTDPSEYLENCRAQEKALKNANAIAKQKRKQTDHIGSDTKKQKVVPLPTDI
Protein: POU class 2 homeobox associating factor 3 (Cancer susceptibility candidate protein 13) (Colorectal cancer-associated protein 2) (Protein OCA-T2) (A8K830)
Organism: Homo sapiens (Human)
Function: Transcriptional coactivator that specifically associates with POU2F3. This complex drives the development of tuft cells, a rare a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24154973}. Nucleus {ECO:0000269|PubMed:35576971}.
Interaction partners:
- POU domain class 2-associating factor 2
Sequence:
MSEKPKVYQGVRVKITVKELLQQRRAHQAASGGTRSGGSSVHLSDPVAPSSAGLYFEPEPISSTPNYLQRGEFSSCVSCEENSSCLDQIFDSYLQTEMHPEPLLNSTQSAPHHFPDSFQATPFCFNQSLIPGSPSNSSILSGSLDYSYSPVQLPSYAPENYNSPASLDTRTCGYPPEDHSYQHLSSHAQYSCFSSATTSICYCASCEAEDLDALQAAEYFYPSTDCVDFAPSAAATSDFYKRETNCDICYS
Protein: ER lumen protein-retaining receptor (O94270)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity).
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- Protein rer1
- Golgi to ER traffic protein 4
- Coatomer subunit beta
- Vacuolar ATPase assembly integral membrane protein vph2
- Surfeit locus protein 4 homolog
- Splicing factor cactin
- Meiotically up-regulated gene 166 protein
- Protein get1
- Putative coatomer subunit alpha
- Synaptobrevin homolog ykt6
Sequence:
MTFFSALGDMAHLAAIFLLLHRMKKSKTCSGLSLKSHLLFLLVYVTRYLNLFWRYKSLYYFLMRIVFIASESYICYLMLMTLRPTYDKRLDTFRTEYILGGCAVLALIYPTSYTISNILWTFSIWLESVAILPQLFMLQRSGETESLTAHYLFAMCLYRGLYIPHWIYRIAVHKKVIGVAILAGIIQTVLYGDFAVVYRRTVLQGKKFRLPA
Protein: Xyloglucan 6-xylosyltransferase 2 (AtXT2) (EC 2.4.2.39) (Putative glycosyltransferase 2) (AtGT2) (EC 2.4.-.-) (O22775)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Xylosyltransferase specific to UDP-D-xylose that accepts both cellopentaose and cellohexaose as substrates, with a better use of cellohexaose, to produce xyloglucan. Adds preferentially the first xylosyl residue to the fourth glucosyl residue from the reducing end of both acceptors. Transfer one xylose mainly to the second glucose residue from the non-reducing end. The acceptor should have a minimum of four glucose residues. Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:22665445, ECO:0000269|PubMed:25392066}; Single-pass type II membrane protein {ECO:0000305|PubMed:25392066}.
Interaction partners:
- Xyloglucan galactosyltransferase MUR3
- Galactoside 2-alpha-L-fucosyltransferase
- Xyloglucan galactosyltransferase XLT2
- Xyloglucan glycosyltransferase 4
- Probable arabinosyltransferase ARAD1
- Cellulose synthase-like protein D2
- Polygalacturonate 4-alpha-galacturonosyltransferase
- Probable xyloglucan glycosyltransferase 5
- Probable galacturonosyltransferase 7
- Galacturonosyltransferase 8
Sequence:
MIERCLGAYRCRRIQRALRQLKVTILCLLLTVVVLRSTIGAGKFGTPEQDLDEIRQHFHARKRGEPHRVLEEIQTGGDSSSGDGGGNSGGSNNYETFDINKIFVDEGEEEKPDPNKPYTLGPKISDWDEQRSDWLAKNPSFPNFIGPNKPRVLLVTGSAPKPCENPVGDHYLLKSIKNKIDYCRLHGIEIFYNMALLDAEMAGFWAKLPLIRKLLLSHPEIEFLWWMDSDAMFTDMAFELPWERYKDYNLVMHGWNEMVYDQKNWIGLNTGSFLLRNNQWALDLLDTWAPMGPKGKIREEAGKVLTRELKDRPVFEADDQSAMVYLLATQRDAWGNKVYLESGYYLHGYWGILVDRYEEMIENYHPGLGDHRWPLVTHFVGCKPCGKFGDYPVERCLKQMDRAFNFGDNQILQIYGFTHKSLASRKVKRVRNETSNPLEMKDELGLLHPAFKAVKVQTNQV
Protein: DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) (P11388)
Organism: Homo sapiens (Human)
Function: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9155056}. Nucleus, nucleoplasm {ECO:0000269|PubMed:8299728}. Nucleus {ECO:0000269|PubMed:17567603, ECO:0000269|PubMed:22013166, ECO:0000269|PubMed:8299728, ECO:0000269|PubMed:9155056}. Nucleus, nucleolus {ECO:0000269|PubMed:9155056}.
Interaction partners:
- Nucleolar and spindle-associated protein 1
- Cyclin-dependent kinase 1
- Abnormal spindle-like microcephaly-associated protein
- DNA topoisomerase 1
- Proliferation marker protein Ki-67
- G2/mitotic-specific cyclin-B1
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Cyclin-A2
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Cell division cycle protein 20 homolog
Sequence:
MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKAKGKKTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELEGLKQRLEKKQKREPGTKTKKQTTLAFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRAATKTKFTMDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLSNKELKPQKSVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDPALNSGVSQKPDPAKTKNRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGESDDFHMDFDSAVAPRAKSVRAKKPIKYLEESDEDDLF
Protein: Low affinity immunoglobulin epsilon Fc receptor (Fc-epsilon-RII) (Lymphocyte IgE receptor) (CD antigen CD23) (P20693)
Organism: Mus musculus (Mouse)
Function: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Secreted {ECO:0000250|UniProtKB:P06734}.
Interaction partners:
- Complement receptor type 2
- B-lymphocyte antigen CD19
- B-lymphocyte antigen CD20
- Immunoglobulin mu Fc receptor
Sequence:
MEENEYSGYWEPPRKRCCCARRGTQLMLVGLLSTAMWAGLLALLLLWHWETEKNLKQLGDTAIQNVSHVTKDLQKFQSNQLAQKSQVVQMSQNLQELQAEQKQMKAQDSRLSQNLTGLQEDLRNAQSQNSKLSQNLNRLQDDLVNIKSLGLNEKRTASDSLEKLQEEVAKLWIEILISKGTACNICPKNWLHFQQKCYYFGKGSKQWIQARFACSDLQGRLVSIHSQKEQDFLMQHINKKDSWIGLQDLNMEGEFVWSDGSPVGYSNWNPGEPNNGGQGEDCVMMRGSGQWNDAFCRSYLDAWVCEQLATCEISAPLASVTPTRPTPKSEP
Protein: P3N-PIPO polyprotein [Cleaved into: P1 protease (EC 3.4.21.-) (N-terminal protein) (P1 proteinase); Helper component proteinase (HC-pro) (EC 3.4.22.45); Movement protein P3N-PIPO (Pretty interesting potyviridae ORF) (PIPO)] (P0CK11)
Organism: Turnip mosaic virus (strain Japanese) (TuMV)
Function: Cysteine protease that cleaves a Gly-Gly dipeptide at its own C-terminus (By similarity). Required for aphid transmission and also has proteolytic activity (By similarity). Interacts with virions and aphid stylets (By similarity). Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity). May have RNA-binding activity (By similarity).
Subcellular location: [Movement protein P3N-PIPO]: Host cell junction, host plasmodesma {ECO:0000269|PubMed:18408156}.
Interaction partners:
Sequence:
MAAVTFASAITNAITSKPALTGMVQFGSFPPMPLRSTTVTTVATSVAQPKLYTVQFGSLDPVVVKSGAGSLAKATRQQPNVEIDVSLSEAAALEVAKPRSNAVLRMHEEANKERALFLDWEASLKRSSYGIAEDEKVVMTTHGVSKIVPRSSRAMKLKRARERRRAQQPIILKWEPKLSGISIGGGLSASVIEAEEVRTKWPLHKTPSMKKRTVHRICKMNDQGVDMLTRSLVKIFKTKSANIEYIGKKSIKVDFIRKERTKFARIQVAHLLGKRAQRDLLTGMEENHFIDILSKYSGNKTTINPGVVCAGWSGIVVGNGILTQKRSRSPSEAFVIRGEHEGKLYDARIKVTRTMSHKIVHFSAAGANFWKGFDRCFLAYRSDNREHTCYSGLDVTECGEVAALMCLAMFPCGKITCPDCVTDSELSQGQASGPSMKHRLTQLRDVIKSSYPRFKHAVQILDRYEQSLSSANENYQDFAEIQSISDGVEKAAFPHVNKLNAILIKGATVTGEEFSQATKHLLEIARYLKNRTENIEKGSLKSFRNKISQKAHINPTLMCDNQLDRNGNFIWGERGYHAKRFFSNYFEIIDPKKGYTQYETRAVPNGSRKLAIGKLIVPTNFEVLREQMKGEPVEPYPVTVECVSKLQGDFVHACCCVTTESGDPVLSEIKMPTKHHLVIGNSGDPKYIDLPEIEENKMYIAKEGYCYINIFLAMLVNVKESQAKEFTKVVRDKLVGELGKWPTLLDVATACYFLKVFYPDVANAELPRMLVDHKTKIIHVVDSYGSLSTGYHVLKTNTVEQLIKFTRCNLESSLKHYRVGGTEWEDTHGSSNIDNPQWCIKRLIKGVYKPKQLKEDMLANPFLPLYALLSPGVILAFYNSGSLEYLMNHYIRVDSNVAVLLVVLKSLAKKVSTSQSVLAQLQIIERSLPELIEAKANVNGPDDAATRACNRFMGMLLHMAEPNWELADGGYTILRDHSISILEKKLSTNLGRSMERVKLVGALCYKILLVKASNLYTERFANEKRSRFRRQIQRVSHVILRTE
Protein: Jmjd2c protein (B0BNJ6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MEVVEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKPMTVKEFRQLANSSKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDK
Protein: Activator of C kinase protein 1 (Q07622)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- RHO1 GDP-GTP exchange protein 2
- Uncharacterized protein YDR239C
- Protein kinase C-like 1
- Inorganic pyrophosphatase
- Protein OS-9 homolog
Sequence:
MVNQGQPQPNLYDKHINMFPPARARESSHKLGNANSDRHGLPAQNIVPAPYPVDDSIVELTPAIPFTSPSSSSSLSLPLSALNFTDGNADGGQLGTPVTINSNNGMDIFNSKPTGEIGYANNGTNSTGSRYELPFNFSSTKESLGSPAVQDASISSGNRISESVRDNSAPPPYEESESRILQEKVYRTEEKAPIRPLNNNPVPPQKINQPPTGSAKTDDNGSSGGEDKLSSYSPEALAFYQVYKKTITDSSKFTPEIQMQWCETLLTYAFNEDFISQYNINAEKLKRSLKPEEMLKNQKVILEHSFKVLTKLITLKWPPAMYLMGTLYSHQPYLPIKNKNIVIKNDEKALEYYCKAAKLNNSDACYRAGVCFEYQRGTSSLDPSPTKEQCIKKAFQYYQHGAEVCSNSACMYKLGMSHLYGLNMQKTDVLLAIKWFDKAAQKGDSPQTLYELGKIYEFSVLPPEIQNLLFANGIRKDSQLAIKYYQQCAKDFEYPLAQWKLGNCYEFGDLGLPVVAKKSIYWYSKAAAAQPKGNPMAMLSLSGWYLTGAPNILKPNNKEAFNWALKSSKCSDGKLARTEFALGFYYEKGVGCEVDLDLAKQYYQRAARMGFRKAVDALRSLTN
Protein: E3 SUMO-protein ligase NSE2 (E3 SUMO-protein transferase NSE2) (Non-structural maintenance of chromosomes element 2 homolog) (Q9VVH7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Structural maintenance of chromosomes protein 5
- SD25546p
- Non-structural maintenance of chromosomes element 1 homolog
- Non-structural maintenance of chromosomes element 4
- MAGE
- DNA repair protein Rad60
- Suppressor of variegation 2-10, isoform I
- Sperm-associated antigen 4
- Degringolade, isoform A
- Small ubiquitin-related modifier
Sequence:
MEFNYLADSALSTLVENKKFFKEMSDFVSDFSDGGKIKKLLEQSVEQSVEHAVNVVHMKIKHQSLNKAMNQVKNSSATIEEFEEVWKERSKAVEQKRINVKNLHEFKNFVKAVESAAGQAGAEVNDQANGTAYDEDLIMEDSGSEVFSFYDPWSKALIKNPMRNKMCGHIYDRDSVMPIIMDRIGIRCPVLGCANLCYIQPDHLVQDANVQQKIQQSMSNAIVDVTASEEDEE
Protein: Large ribosomal subunit protein uL4A (60S ribosomal protein L4-A) (L2) (RP2) (YL2) (P10664)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL4 participates in the regulation of the accumulation of its own mRNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102, ECO:0000269|PubMed:25936803}. Nucleus {ECO:0000269|PubMed:25936803}.
Interaction partners:
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein uL23
- Ribosome biogenesis protein NOP53
- Large ribosomal subunit protein uL2A
- Small ribosomal subunit protein RACK1
- Large ribosomal subunit protein uL13A
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein uL3
Sequence:
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLKHD
Protein: Eyes absent homolog (EC 3.1.3.48) (A0A0R4IA41)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Homeobox protein six1b
- SIX homeobox 5.
Sequence:
MENTQDLNEQSVKKSTTDSHAPDPVDNRALEMQELTDVQHSVNSGSDGTSKLDKNILSNNITTNGTGGENMTILNTADWLLGCSSPPTAPSMKNDVKSEPLNSSEAVSSAGDSGLDTYTGSVISSSGFSPRPAHQYSPPLYPSKPYPHILTTPVAPPMSAYTGQSQFSSMQQSTVYTPYSQTTPPYGLSTYDLGVMLPGIKTEGGLTQTQSTLQSGLSYSPGFTTPQPGQTAYSPYQMPGSGFTTSPGLYTSNNSNPGNFTTQQQEYPSYTTFGQNQYAQYYSTSSYGSYMTSNSSLDGTGSVSTYQLQDPIMTGQAADLNPGEFEAGQSPSTPIKEMEDRACRGGGAKARGRGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATSASLCLATGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL
Protein: Nuclear pore complex protein (NUP155), putative (Q38AE7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nucleoporin
- Nucleoporin
- Nuclear pore protein
- Uncharacterized protein
- Nucleoporin NSP1-like C-terminal domain-containing protein
- Protein transport protein Sec13, putative
- Nucleoporin
- Poly
- Long-chain-fatty-acid-coA ligase protein,putative
- Telomerase-associated protein, putative
Sequence:
MEVRDDNPSRIEDATKRAVEEIISAEIRSAAISKDNTISPCGHVSSHPFALTTFDTSSTLPAFLPLTGVTWPEAVKAVWKTFRANSTVGLFPELSRAWITIDNKLLLWNFGTGRDFFLFDEVPELIVAVGTPVLPIAGVFQAHITYVLPVSTPKAVHLLGLCVFGGGPLKKAELYVVSLGFSVMAPALFTKLVGVKELGRIFAAGADGCLYEVKYAKEDTAFLPKLRLVNCSLMFGSVPVLGAVSSLISAIKQTWAKERPALRDVAIEAKRKLLFTLNSESTISLWRITNDGLSQLATVRGGALGGTNRTSVWSGGAGVELARIFCATSSDDSCSLIAVAANGEQYRYVCQDGLWGGADASLSLRESLGSYIPQGREVTVCFASEGISVVCHAEKSEGGYSPDSVTVASSHKGILQPHHNCRDIVAQFEPEATCMTRVDAISEVPVEGGVSPNELCSQVSCSPRQFVFLHRHGVSTFIKLRPVDTLHMIIASSSEQVRDSLLQRLSSIYSASDYCCMLVQIAVGCTNVPVTVDGPYVERGDANASFSPAGKGNGKSQIPLSVEQLGRQLNETPSQEVQRIAREILRSAMAPSWYEGPGPDDGTRHIVVQVSPFASGVLAYISRALYAVWNTALEGVTMRELAVVETALSSVVRLLNSLKRDVWSDKFVQPAVPFQWDKGKVTLVLPPHRSSISSYDIKMLQSALLCSSHTLCERVLQTIKFLKQTAAVPPMAEDGKVTVAQIVSDQSVAHRMARHVGKVVLSSEKGAGYLPQDGVGSVMQLQLECPYFFNSIDVQEYNVRVELERLLSANGENFHAFPEGKMAEWESSVSVMAASLWYSGALLDICQQLRALKKEGTAVKLLLHAACQLDPNNSAFKTYLAERSGNLNQAVSSAVGSTYQQKLKVLGEVVSTLENAWNTHRSTVDGLLGGPLSSGAIWQIEPTDELAHCYLFDWLCLPRDDAHIKAMLRETLVAAHSPFIEAYLQRNISTLGEQYVRYLRKTKKNHALAIEVCASVVHAPLTGIPREERISYRLRCLAEAKGSAEESKSDQLKSLEQRIGLMEAQLHLSKIICEFINSGHSHLDRRVAVDGRGLMTERQIALEQMEMVENHVLSTVQLLQVAGMFCAYGGAEVQLDVLNAANVTDSSLHAACIDRCFQRKDATVEEIARRVIGKCMRTIASPLCHVVKILEAYAFQRSPEGSTLTVDVLYDCGVEHNVIFSTIAAIFDKRDFLTAPCETFDQSAVTDAFLVHSLAAALHRAVFASHISSVQMYFLGNALNTVREGISKVAIQPGDERSIRALSAAEGLLEQCNLALNRASSRFTF
Protein: DNA-directed RNA polymerase, mitochondrial (EC 2.7.7.6) (O13993)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Combines in the mitochondrion with mitochondrial transcription factor mtf1 as a holoenzyme to recognize and initiate transcription at the core mitochondrial promoters.
Subcellular location: Mitochondrion.
Interaction partners:
- Mitochondrial transcription factor 1
- Dimethyladenosine transferase
- Non-histone chromosomal protein 6
- ATP synthase subunit a
- Pentatricopeptide repeat-containing protein 2
- Single-stranded DNA-binding protein rim1, mitochondrial
- Pentatricopeptide repeat-containing protein 6
- Pentatricopeptide repeat-containing protein 5
- Probable DNA-directed RNA polymerase I subunit RPA2
- DNA polymerase gamma
Sequence:
MLRRKIQTYLSRSHIRRGLCGLRFFQTQRLHTDYMPIEAYEPYKNELKSKIGKDFIIDLSYKSGTASLFEACVYNGDFLRSKQLLKSFIDHNKGDKILLPMINLYIREIIQRGSFELTDVLSNAKELLQQARLNGDSLTYALLCQASLNPTQRQLGLPVLHELIHNWRSANGKVIDILMHESVFSPEEVKLIMDQLNIPINNFTPSQLQLLGITNSTIVGESENGKDQNGDSSLKEKQPDVETTVTKSANLNALRSSLSSLLTESIDLPIDEVSLEFGNQGDTFNLARQKLLEKSAILSAAEVWKSEHESVLNRGNLQVPKNVSSLFYSWYVQLEQLFKEEISLIDDLALNESLDKKNDRLIYGPFLKLLSSKKLAALTIMEVAQLSTNPRYDRGARVTTLLGGLGRSFEREFLSEQIQRQEKNKSYKDKKRLKELFNDPRKFRQAVKNLRLSNTRDNIVLNPSVDSWPSAIVMKVGSVALCLLLSVAKIEVTAKDLSTGGILKQEVAAFVHTYQYSNGRKVGMIVPHVEFYKLLSRDIEKPHLHPQLLPMLVTPKPWTSWIDGGYYYSRQPLVRLKGALEQVDYLMKASENGQLDELFKAVSSLGKVSWRINQRLFNVLIRIWNSGEKFLSIPPREVKCDMPPYPKNSINPRDKVIWHTRRKELAALKTGAHSQRCDFNYKLEIARAFLNEKFYFPHSLDFRGRAYPLSSHLHHVSNDVCRGLLEFSTGKPLGPKGLNWLKVHLANLFGISKKDFATRQAFVDDNMQEVFDSADRPLDGNKWWSKADDPFQALAACFEIAEAVRSGDHESYISHIPIQQDGTCNGLQHYAALGGDIEGAKQVNLWPSDHPSDVYEAVAEIVRGFLKKDAEAGDEMANFLKDKVTRSVVKPTVMTNVYGVTYVGARKQISEKLENIDGMEKLKVADYANYLTKKVFEALRSLFTQAHEIQDWLSACCNLITHSLPADYIKEGIKDELTPVVWTTLLNLPIVQPYRNYKSRQIRTNLQTVFIEERDRTATVQPHKQATAFPPNFIHSLDATHMFMTCLKCSEQNINFAAVHDSYWTHACDVDQMNSLLREAFVLLHSNNIMERLKQEFEERYKGFLVSKKAIKANDEDLKAKFGNKSYIPLEFPPLPARGALDLKKVLESKYFFS
Protein: C-C motif chemokine (Q91Y39)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU361150}.
Interaction partners:
Sequence:
MQQAGLTLVAVAVCVAFRTSEAILPIASSCCTEVSHHIPRRLLERVNSCSIQRADGDCDLAAVILHVKRRRICVSPHNPTLKRWMSASEMKNGKENLCPRKKQDSGKDRKGHTPRKHGKHGTRRIHGTHDHEAPR