wanglab/gogpt-training-data huggingface dataset:
Protein: Nuclear receptor subfamily 1 group D member 2a (Nuclear receptor subfamily 1, group D, member 2a) (F1QIC9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU004334}.
Interaction partners:
- Nuclear factor, interleukin 3-regulated, member 6.
- Period circadian clock 1a.
- Nuclear factor, interleukin 3 regulated, member 5 isoform X1
- Basic helix-loop-helix family, member e40.
- Nuclear receptor corepressor 2
- Cryptochrome-1
- Dec2)
- Nuclear receptor subfamily 1 group I member 2
- Nuclear receptor subfamily 1, group H, member 3
- Period homolog 1b
Sequence:
MESAKQGGVIAYVCSSSSASSPESCMSDSSASQSPSSSPPLPTKASRATDLSISAGMLKHTRGHTSDKSLANKSSITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKTESCTIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLLEMQTAMNNMMNNSQLQHMLHVSPSDSSSSSSASPPDSPRSSTESLVPMDTASSCSSDSGEEDGRFSYSASVSPAASETLSREEEEPQMQCWRRSDCQNTTGPYREQTAQQCIRLPTENMSYCRRNMNEGGNRAHLVCPMSASPFVDASRPGHEVWEEFSRSFIPAVREVVEFAKRIPGFQELSQHDQVNLLKAGTFEVLMVRFVPLFDVQQRTVSFMSGRRYSVDLLRSMGAGELLNCMFEFSEKLAALQLNDEEMSLFSAVVLVSADRSAIEDVVGVEALQESLIRALRNLIMKNHSNESSVFTKLLLKLPELRSLNNMHSEELLAFKIQP
Protein: HTH-type transcriptional regulator PchR (Pulcherriminic acid biosynthetis regulator) (P40762)
Organism: Bacillus subtilis (strain 168)
Function: Represses the expression of the yvmC-cypX operon, which is involved in pulcherriminic acid biosynthesis. Also negatively regulates yvmA, yvnB and its own expression. Positively regulates yisI expression. Acts by binding specifically to a 14-bp palindromic motif, the YvmB box, which is present in the promoter region of the target genes.
Interaction partners:
- Uncharacterized MFS-type transporter YvmA
- Pulcherriminic acid synthase
- Cyclo
- Uncharacterized protein YvnB
- Uncharacterized protein YckD
Sequence:
MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVAEIPKNMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEVYFKLTRKGRRIFDLHEKLHKKKELAFYQFLDSFSQEEQKAVLKFLEQLTSTLEAEQTDGTPDKPVK
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q38G47)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MQSSQWLQPLVLFVMTVILATALKRVDAATGVGIKKSTWEPLCQVSEELDGIAGHVLQEATEMIAATIDFDAAAKRARIFSLKNPMHKWTKAAITIATAYEAKAAAAVRQLKDTYIKQQVEAASRSAYVKGRVDDFLKLLEQTVDGSNNACLLADENADTPVTRSATTKLGQTECKLTQSSITATRRTPTHITTAGYINLVEGTGGDKHQPTAASKECHLTTAHTSKGFAKGEGTAAAVTVMAGYLTIPNSAAELTAATKANLITASEGGIAAWSHAHAAIKLLDRTLPTEYANESGDLTERAALKEAAQNLFGEAKDHQGSDGKKAIEAVFSNTKADTINTIITLIEKEDIPKGAAARPTPAKLGEIKNSIELTNLLSYYQQRLSQDFETLDKRLEESTKHQDPKATEKICGEAKDDEDKCKGLKDKGCSFNEQDKKCELKKDVKEKLEKSNQETEGNDGKRTNTTGSNSILIHKSPLLLVVLLLK
Protein: Peroxisome biogenesis factor 2 (EC 2.3.2.27) (EC 2.3.2.36) (Peroxin-2) (E7F4V8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity). The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase (By similarity).
Subcellular location: Peroxisome membrane {ECO:0000250|UniProtKB:P28328}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Peroxisome assembly protein 12
- RING-type E3 ubiquitin transferase
- Peroxisomal membrane protein PEX13
- Peroxisomal biogenesis factor 19.
- Peroxisomal biogenesis factor 14.
- Peroxisomal biogenesis factor 3.
- Peroxisomal biogenesis factor 5-like a.
- Peroxisomal biogenesis factor 5.
- Peroxisomal biogenesis factor 5-like b.
- Peroxisomal biogenesis factor 7.
Sequence:
MAGAGGDKPFAKAGPSPLSRVLRISQLDAFELDGALEQLVWSQFTQCFQHFKPGILTPVEPELKALLQLLLWRFTIYSNSATVGQSLLNIRYKNALIPGQKYRPMSRPQKFWFALLTVGEKWFRERSHSLFLNHPAESNARKARKVLSILLGLTKAASLVNFLLFLQRGTFPTLTERLLGVQPVFSRPQGPRDINFQYLNRELLWHGFAEFLIFLLPLINVWKLKAGVSALFSPLSDLTGTQSSEETHLTECAICGEWPTMPHSIGCKHVFCYYCVKSNVIADIYFTCPKCGAETGQIEPVRLQVGTELLQS
Protein: Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Q383W8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03008}.
Interaction partners:
- RNA-binding protein, putative
- Elongation initiation factor 2 alpha subunit, putative
- Eukaryotic translation initiation factor 5, putative
- protein-synthesizing GTPase
- Translation initiation factor, putative
- CSN8/PSMD8/EIF3K domain-containing protein
- Translation initiation factor, putative
- Eukaryotic translation initiation factor 3 subunit 7-like protein
- Eukaryotic translation initiation factor 3 subunit L
- Eukaryotic translation initiation factor 3 subunit 8, putative
Sequence:
MNIQGMALHGHMKPVTMIKFNREGDLLFSTAKEPNVSVWYTKTGERLGTYDGHSAISACDVNNYSTLLVTGGMDFKAKLWCVETGEELANIMLRTPARAVGFSHDDNLLMVSTSRKMGQKSAVQLYNLPFLPPKDGYSIHPVNTVFNPCTEFVSENDDVTFAIWGPTNDTIYYSTSDGSVAILDVETMSTVCTHKPHEETINRISFDSNYYTLITASKDKTARLLDSRDLSVVQTYTSDVPVNDASISPRGDHVIIGGGMDAQDVTTQGGQTTFEVKFYHKVHEKQLGQVRCHFGTINSVCFFPDGRGFASGAFDGLVKLHRFDDKYSSTPGAIPLWTPEGI
Protein: Ribosome assembly protein rrb1 (Q9P783)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in regulation of L3 expression and stability and plays a role in early 60S ribosomal subunit assembly. May be required for proper assembly of pre-ribosomal particles during early ribosome biogenesis, presumably by targeting L3 onto the 35S precursor rRNA (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable assembly chaperone of rpl4
- Uncharacterized WD repeat-containing protein C25H1.08c
- Periodic tryptophan protein 2 homolog
- Pre-rRNA-processing protein tsr2
- Ribosome biogenesis protein erb1
- Ankyrin repeat-containing protein P16F5.05c
- U3 small nucleolar RNA-associated protein 21 homolog
- Probable U3 small nucleolar RNA-associated protein 13
- Probable U3 small nucleolar RNA-associated protein 18
- Ribosomal RNA-processing protein 14-N
Sequence:
MSKRAAEETVEFNSKNGPGQRGTVADNVDTEMGEFEDAYEDEIESEEEYIEADGEKDNGMDEEEQNDAQPSKIPWLPGGKINADEKLVADPSVYEMLHNIQVKWPFLSFDILQDSLGEERRAWPHQMYLVGGSQALDSNDNELTVMKLSQLYKTQHDENDDASDNSDVEEDPILEHKSISTKGACNRVRSARRPANSSKESLLASFHETGKVHIWDIAPHLRSLDSPGVMVSRKENSPLYTVNRHKTEGYALDWSPFEYSLLSGDNANEIFLTKYSNGGWQTDSSPFLSHTAAVEDLQWSPSEKNVFSSCSCDGTFRIWDVRNKQKTSALTVNAHPGVDVNVLSWNTRVPNLLATGADNGVWSVWDLRSLKSSSSVATPVASFKWHRAPIYSIEWHPNEDSVIGVVGADNQISLWDLSVELDEEEQDSRAAEGLQDVPPQLMFIHMGQQEIKEMHWHRQIPGTIVSTAMTGINVFKTITF
Protein: p44-8 outer membrane protein (Q2GLI2)
Organism: Anaplasma phagocytophilum (strain HZ)
Interaction partners:
- p44 outer membrane protein, N-terminal
Sequence:
MLRLMVMVVLQGSGRAGYFYVGLDYSPAFSKIRDFSIRESNGETKAVYPYLKDGKSVKLESNKFDWNTPDPRIGFKDNMLVAMEGSVGYGIGGARVELEIGYERFKTKGIRDSGSKEDEADTVYLLAKELAYDVVTGQTDNLAAALAKTSGKDFVQFAKAVVVSHPGIDKKVCATKAQSSGKYGKYADKTGTKSSDNNTSLCSDDGGSHSGSSNNAEVFEHFIKKTLLENGSKNWPTSTKNDGAPSDNKNDNADAVAKDLTKLTSEEKTIVAGLLAKTIEGGEVVEIRAVSSTSVMVNACYDLLSEGLGVVPYACVGLGGNFVGVVDGSRRTIRF
Protein: Putative uridine kinase DAS2 (EC 2.7.1.48) (DST1-delta 6-azauracil sensitivity protein 2) (Regulator of rDNA transcription 3) (Q12084)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Putative uridine kinase identified in a screen for mutants with increased levels of rDNA transcription.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Uridine kinase
- Uridine nucleosidase
- Cytidine deaminase
- Uridylate kinase
- Uracil phosphoribosyltransferase
- Orotidine 5'-phosphate decarboxylase
- Golgi apyrase
- Sedoheptulose 1,7-bisphosphatase
- Ribulose-phosphate 3-epimerase
- S-formylglutathione hydrolase
Sequence:
MDRKAVEEKRIVISIGGGHATGVGAIALDLQNTFKSLYNSINIRVINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDPIDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPSTNENLGRAVLVDGIVKAIEDTKSQIEGNNTNNKIRPRLWDFEAETMDLEKDRYYDLS
Protein: CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains) (Q9Y5K6)
Organism: Homo sapiens (Human)
Function: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. Plays a role in epithelial cell junctions formation.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15800069}. Cell projection, ruffle {ECO:0000269|PubMed:10339567}. Cell junction {ECO:0000269|PubMed:22891260}. Note=Colocalizes with F-actin and BCAR1/p130Cas in membrane ruffles (PubMed:10339567). Located at podocyte slit diaphragm between podocyte foot processes (By similarity). During late anaphase and telophase, concentrates in the vicinity of the midzone microtubules and in the midbody in late telophase (PubMed:15800069). {ECO:0000250|UniProtKB:Q9JLQ0, ECO:0000269|PubMed:10339567, ECO:0000269|PubMed:15800069}.
Interaction partners:
- Nephrin
- Podocin
- Kin of IRRE-like protein 1
- T-cell surface antigen CD2
- E3 ubiquitin-protein ligase CBL
- Tight junction protein 1
- Ras and Rab interactor 3
- Synaptopodin
- F-actin-capping protein subunit alpha-1
- Src substrate cortactin
Sequence:
MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS
Protein: Transcription initiation factor TFIID subunit 8 (TBP-associated factor 8) (B4DZU5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPSLLPSELEMQQMEETDSSEQDEQTDTENLALHISMEDSGAEKENTSVLQQNPSLSGSRNGEENIIDNPYLRPVKKPKIRRKKSLS
Protein: Subtilisin-like protease SBT3.3 (EC 3.4.21.-) (Subtilase subfamily 3 member 3) (AtSBT3.3) (Q9MAP5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine protease that plays a role in the control of the establishment of immune priming and systemic induced resistance.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:23818851}.
Interaction partners:
- AT5g45310/K9E15_9
- Aspartyl protease AED1
- Aspartic proteinase CDR1
- Proteasome subunit beta type-6
Sequence:
MRSFRSSILLVLLSLITVLNATRARSETESKVHIVYLGEKKHHDPEFVTESHHQMLASLLGSKKDADDSMVYSYRHGFSGFAAKLTKSQAKKIADLPEVVHVIPDGFHELATTRTWEYLGLSSANPKNLLNDTNMGDQVIIGVIDTGVWPESESFNDNGVGPIPRKWKGGCESGENFRSTDCNRKLIGAKYFINGFLAENKGFNTTESRDYISARDFDGHGTHVASIAGGSFVPNVSYKGLAGGTLRGGAPRARIAMYKACWFHEELKGVTCSDSDIMKAIDEAIHDGVDVLSISLVGQIPLNSETDIRDEFATGLFHAVAKGIVVVCAGGNDGPAAQTVVNIAPWILTVAATTLDRSFPTPITLGNNKVILGQATYTGPELGLTSLVYPENARNNNETFSGVCESLNLNPNYTMAMKVVLCFTASRTNAAISRAASFVKAAGGLGLIISRNPVYTLSPCNDDFPCVAVDYELGTDILSYIRSTRSPVVKIQRSRTLSGQPVGTKVVNFSSRGPNSMSPAILKPDIAAPGVRILAATSPNDTLNVGGFAMLSGTSMATPVISGVIALLKALHPEWSPAAFRSAIVTTAWRTDPFGEQIFAEGSSRKVSDPFDYGGGIVNPEKAAEPGLIYDMGPQDYILYLCSAGYNDSSISQLVGQITVCSNPKPSVLDVNLPSITIPNLKDEVTLTRTVTNVGLVDSVYKVSVEPPLGVRVVVTPETLVFNSKTISVSFTVRVSTTHKINTGYYFGSLTWTDSVHNVVIPLSVRTQILQNYYDEN
Protein: Melanophilin (Exophilin-3) (Slp homolog lacking C2 domains a) (SlaC2-a) (Synaptotagmin-like protein 2a) (Q9BV36)
Organism: Homo sapiens (Human)
Function: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
Subcellular location: Cytoplasm.
Interaction partners:
- Unconventional myosin-Va
- Ras-related protein Rab-27A
- Ras-related protein Rab-27B
- Synaptotagmin-like protein 2
- Exophilin-5
- Rabphilin-3A
- Melanoregulin
- Ras-related protein Rab-3A
Sequence:
MGKKLDLSKLTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQPYQLLVNSKRQCLECGLFTCKSCGRVHPEEQGWICDPCHLARVVKIGSLEWYYEHVKARFKRFGSAKVIRSLHGRLQGGAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEARDSPQSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAALGSNVIRNEQLPLQYLADVDTSDEESIRAHVMASHHSKRRGRASSESQIFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEEALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAVPYLLRRKFSNSLKSQGKDDDSFDRKSVYRGSLTQRNPNARKGMASHTFAKPVVAHQS
Protein: Epidermis-specific secreted glycoprotein EP1 (52/54 kDa medium protein) (Q39688)
Organism: Daucus carota (Wild carrot)
Function: May be involved in the limitation of water flow through the outer epidermal cell wall, either by direct modification of wall structure or as a signal instructing the protoplast to restrict water transport across the cell wall.
Subcellular location: Secreted {ECO:0000269|PubMed:8275102}.
Interaction partners:
Sequence:
MARFFPLTLTILLFFIQRIDFCHTLVPANETFKFVNEGELGQYISEYFGDYRPLDPFTSPFQLCFYNQTPTAFTLALRMGLRRTESLMRWVWEANRGNPVDENATLTFGPDGNLVLARSNGQVAWQTSTANKGVVGLKILPNGNMVLYDSKGKFLWQSFDTPTDTLLVGQSLKMGAVTKLVSRASPGENVNGPYSLVMEPKGLHLYYKPTTSPKPIRYYSFSLFTKLNKNESLQNVTFEFENENDQGFAFLLSLKYGTSNSLGGASILNRIKYNTTLSFLRLEIDGNVKIYTYNDKVDYGAWEVTYTLFLKAPPPLFQVSLAATESESSECQLPKKCGNFGLCEESQCVGCPTSSGPVLAWSKTCEPPKLSSCGPKDFHYNKLGGWITT
Protein: SPX domain-containing protein 4 (Protein SPX DOMAIN GENE 4) (AtSPX4) (Q94A21)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein PHOSPHATE STARVATION RESPONSE 1
- Protein NRT1/ PTR FAMILY 6.3
- Phosphate transporter PHO1
- Phosphate transporter PHO1 homolog 9
- Bromodomain testis-specific protein
- Transcription factor HRS1
- Phosphate transporter PHO1 homolog 2
- Probable ubiquitin-conjugating enzyme E2 24
- Phosphate transporter PHO1 homolog 10
- Phosphate transporter PHO1 homolog 7
Sequence:
MKFGKEFRTHLEETLPEWRDKFLCYKPLKKLLKYYPYYSADFGPANSDHNDSRPVFADTTNISSAADDGGVVPGVRPSEDLQGSFVRILNDELEKFNDFYVDKEEDFVIRLQELKERIEQVKEKNGEFASESEFSEEMMDIRRDLVTIHGEMVLLKNYSSLNFAGLVKILKKYDKRTGGLLRLPFTQLVLHQPFFTTEPLTRLVRECEANLELLFPSEAEVVESSSAVQAHSSSHQHNSPRISAETSSTLGNENLDIYKSTLAAMRAIRGLQKASSTYNPLSFSSLLQNEDDETVTAENSPNSGNKDDSEKEDTGPSH
Protein: 2-acylglycerol O-acyltransferase 1 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 1) (MGAT1) (Diacylglycerol O-acyltransferase candidate 2) (hDC2) (Diacylglycerol acyltransferase 2-like protein 1) (Monoacylglycerol O-acyltransferase 1) (Q96PD6)
Organism: Homo sapiens (Human)
Function: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q91ZV4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q91ZV4}.
Interaction partners:
- Diacylglycerol O-acyltransferase 1
- Phospholipid phosphatase 4
- Monoglyceride lipase
- Phospholipid phosphatase 5
- Lipoprotein lipase
- 2-acylglycerol O-acyltransferase 3
- 2-acylglycerol O-acyltransferase 2
- Diacylglycerol O-acyltransferase 2
- Acylglycerol kinase, mitochondrial
- Phospholipid phosphatase 2
Sequence:
MKVEFAPLNIQLARRLQTVAVLQWVLKYLLLGPMSIGITVMLIIHNYLFLYIPYLMWLYFDWHTPERGGRRSSWIKNWTLWKHFKDYFPIHLIKTQDLDPSHNYIFGFHPHGIMAVGAFGNFSVNYSDFKDLFPGFTSYLHVLPLWFWCPVFREYVMSVGLVSVSKKSVSYMVSKEGGGNISVIVLGGAKESLDAHPGKFTLFIRQRKGFVKIALTHGASLVPVVSFGENELFKQTDNPEGSWIRTVQNKLQKIMGFALPLFHARGVFQYNFGLMTYRKAIHTVVGRPIPVRQTLNPTQEQIEELHQTYMEELRKLFEEHKGKYGIPEHETLVLK
Protein: Uncharacterized protein (Q583J9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MADNSSASSPAQVVATVRHENILLKKCLAEVRHENQLLKKQLYRLSAILDIALSKLASKGITLETPVSIRELRAAIPSRDVIDMPAETLTSADVNYENNPVPSVPNRRFQLRREMREHTKPVQCVAFAPGDMPLLATGGLDCRLILHDFWTGEKVHAIHGHEQNVADVAWFEGSGNLLSASFDSTVKVWDPRHMSGSPSPIYQLKSKGFVLSAVPLDKAYTLVCTDSKRYTSIVDIRTKKTISWRHDVRVNTLAFNGSKTQLVTGHNNGQIAIWDLRKVGSMLSSSMEGEGPNGGSQAVVDQTSVAHIPRLASVENEPSQSPITHISFYHNRDDSKRLVVVSADNMVRLYYEPGINPSLPHELMLRNVVGGVPTRGYTSKAAFWKGVREEQNVPAFFDDGEREGEAPSRRLTECDLMVTCGADNTACIYDVTERGNAVLVERLEGHRDRVVGAATHHADSKPIIATYSADNTVRTWVPVKT
Protein: Heparan sulfate 2-O-sulfotransferase hst-2 (Heparan sulfotransferase 2) (EC 2.8.2.-) (HS2ST1 homolog) (O17645)
Organism: Caenorhabditis elegans
Function: Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). Involved in cell adhesion and guidance by specifically modifying proteoglycans in the extracellular matrix and on the cell surface that are essential for axon migrations.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8R3H7}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8R3H7}.
Interaction partners:
- Heparan-sulfate 6-O-sulfotransferase
- D-glucuronyl C5-epimerase
- Sulfotransferase domain-containing protein
- Sulfotransferase domain-containing protein
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
- Probable syndecan
- GlyPicaN
- Exostosin-1 homolog
- LONg
- Exostosin-like-3 homolog
Sequence:
MLWKKRKVLYFAGISVFILILLLLKLNSKPKANVWPTSSKIVIYNRIPKTGSTTFTNAIAYDLYKENGFSVLHVNMTKNRQVMSLPDQYTFVNNITTWTERLPAFYHGHVAFIDFQRFGIANPIYINIIREPLERLLSHYYFLRYGDNYRIGLKRSRAGNNETFDECYSRGGKDCDMKQMWIQIPYFCGHYHFCTEVGNPEALRVAKQNVLEKYLLVGTTSRMRDMIALLEVTVPDFFKGALGHFDSLDANRAHLRYTKKKIPPNDQTLSMIRRDEVYKMEREFYDFINNLFDAVFKKATNGISKADDLVKLPLQYHFEKIKPS
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (A0A1D8PLU4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- SnoRNA-binding rRNA-processing protein
- Nan1p
- RNA helicase
Sequence:
MYQSSSSKPKLNINNNSTTITTNPTTTLNPLLFATPLNFKPASTSTTLSTGFDNHIPKSYIVLSNNSNNSSMKTSKKLGKSNTKKTTNDPPKPKSLNEAIANYTGNKYLTHKERKRKRKLQEIINEDNQVPKEDQQEQGEDDEEEEETDEAKHVTKKVKKGMWDSIKSFWSSTPTSTPTPPTEEEEEDLGENIEEKQEEKEEEEENEDDDSSSPGEVFTETSPFTGFSEPEKSEIDEEDEEDDADFVDEESGSPESGDEDDEDVESDSMSPQASDDDDEDEDLEKLKYDLKIDQLVNDKDVNEDEEEEEEEEEEEEETQERTSTTPPTSPEEDTEKQQPEPSEVSYYDINEYEDDRGSNNSTRIYKNWRELANKKPPVGLLNHGVTCYMNSAIQSIIHIPAMQHYLNDVNDNKYSQLKPRSVTHVLAELSKRMWLASNTNNNKKGKSNGGIKYINPKKIIQRLDEINCMMSEWQQEDSHEYYMSLISRLQEDSTPKGKKLNESIIYDIFGGLLNQRITCHKCHNVSITKQEFYDLSLGLNKKKIKSNNNGDNITNDSNNDTTSTTATSTSTSDPIFNSNKFSVEKSINDFFSNEVIKKSENDSKSGYFCEKCNRFTHANKISSIEIAPETLTIHFKRFKFNNNSSSKVKQSINYSKYLDLSKYMVQGTAKYRLTSVIVHEGRSISSGHYVAHCLQPDGYTWCTYDDEYINKIEERVALNDPSAYVLVYTKLTPKV
Protein: Citrate synthase (F8W4S1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MALLTAAARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSE
Protein: NmrA-like family domain-containing protein 1 (I3L0Y6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVDKKLVVVFGGTEIWFHHVAQAGLKLLSSRDLRASASQSVWITGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAEVVQGDQDDQVIMELALNGAYATFIVTNYWESCSQEQEVKQGKLLADLARRLGLHYVVYSGLENIKKLTAGRLAAAHFDGKGEVEEYFRDIGVPMTSVRLPCYFE
Protein: Hephaestus, isoform Z (A0A0B4LHY1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMSCPIPMPMPISSLHKSEFEPVNIGVKRGSDELLSQAAVMAPASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQTTAPAMRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI
Protein: Exocyst complex component 7 (Exocyst complex component Exo70) (O35250)
Organism: Mus musculus (Mouse)
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:12687004}. Cell membrane {ECO:0000269|PubMed:12687004}; Peripheral membrane protein. Midbody, Midbody ring {ECO:0000250|UniProtKB:Q9UPT5}. Note=Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ (PubMed:12687004). Colocalizes with CNTRL/centriolin at the midbody ring (By similarity). {ECO:0000250|UniProtKB:Q9UPT5, ECO:0000269|PubMed:12687004}.
Interaction partners:
- Exocyst complex component 6
- Exocyst complex component 2
- Exocyst complex component 8
- Exocyst complex component 1
- Exocyst complex component 4
- Exocyst complex component 5
- Exocyst complex component 3
- Rho-related GTP-binding protein RhoQ
- Exocyst complex component 6B
- Exocyst complex component 1-like
Sequence:
MIPPQEASARRREIEDKLKQEEETLSFIRDSLEKSDQLTRNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLLLDLISADDELEVQEDVVLEHLPESVLRDVVRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLEGRDDMLDVETDAYIHCVSAFVKLAQSEYRLLMEIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQVLGDTYNIPLDPRETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKVWAIPDTEQRDKIRQAQKDIVKETYGAFLHRYGSVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA