wanglab/gogpt-training-data huggingface dataset:
Protein: Natural resistance-associated macrophage protein 2 (Solute carrier family 11 (Proton-coupled divalent metal ion transporters), member 2) (Q1RLY4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Late endosome membrane {ECO:0000256|ARBA:ARBA00004107}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004107}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004155}.
Interaction partners:
Sequence:
MKTGRDGDALDESVPQEPDLYSPVSPVPQEEPVSTYFEEKVPIPDDGTEKLFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLGATIIGLLLQRLAARLGVVTGMHLAEVCNRHYPTVPRIILWLMVELAIIGSDMQEVIGCAIALNLLSVGRIPLWAGVLITIVDTFVFLFLDKYGLRKLEAFFGFLITIMALSFGYEYVRVAPDQAAVLQGMFLPYCRGCGPSQLEQAVGIVGAVIMPHNIYLHSALVKSRDINRSNKKEVKEANKYYFIESSIALFVSFLINVFVVAVFAEAFYGKTNMEVSQQCNETGSPHTDLFPANNETLEVDIYKGGVVLGCFFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIFPTLLVAVFQDVQHLTGMNDFLNVLQSMQLPFALIPILTFTSLTSLMHDFANGLVWKIGGGLLILLVCAINMYFVIVYVTDLNSTVLYVLAALLSIAYLSFVIYLVWQCLLALGVSALACGSSAEFPAAALIQEQPEFDS
Protein: Roundabout guidance receptor 2 (D3ZEC8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTPLMFTLLLLFGFLCIRTDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGTYVCVARNYLGEAVSRNASLEVACKCL
Protein: Iroquois homeobox-like protein 1a (Mohawk homeobox a) (A5YC44)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MNTIVFNKLSSQVLFEEKANEVERSSRNYLEVIDGQHPDLLSSSPVLKDSSAIRHRRSGSRQNPGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSDDADPATRAQVGEFSKPMYQSVIKKEGGGMGAGLRAASDASLADDYVSPPKYKSSLLHRYLNDSLRHVMGANGVMDARKRNHSGSFSSNEYDEDLLSPSSSEAEANFIYRTETVEHGSNKCDRSLQKEKGQRKDETYWREINAAMAPTNLAQPKGTATAGTTTSCIIQKSSHIAEIKTVKVPLLHKY
Protein: GATA transcription factor 18 (Protein HANABA TARANU) (Q8LC79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional factor that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (including its own promoter and GATA21 promoter), thus regulating the expression of genes mostly involved in hormone responses and floral organ specification (including genes regulating hormones responses). Regulates both flower and shoot apical meristem (SAM) development, especially for establishing organ boundaries in shoots and flowers, probably by controlling the number and position of WUS-expressing cells. Coregulates, with AGO10/PNH, the shoot apical meristem (SAM) organization. Regulates floral organ development via the promotion of JAG and NPR5/BOP2 expression. Modulates cytokinin homeostasis in organ boundaries by regulating CKX3 expression. Involved in cell proliferation and differentiation. Required to position the inductive proembryo boundary via the regulation of gene expression and for early embryonic development. Together with GIF1/AN3, mediates cotyledon identity by preventing ectopic root formation through the repression of PLT1 expression.
Subcellular location: Nucleus {ECO:0000269|PubMed:20643354}.
Interaction partners:
- RING-type E3 ubiquitin transferase
- At1g76620/F14G6_22
Sequence:
MMQTPYTTSTQGQYCHSCGMFHHHSQSCCYNNNNNSNAGSYSMVFSMQNGGVFEQNGEDYHHSSSLVDCTLSLGTPSTRLCEEDEKRRRSTSSGASSCISNFWDLIHTKNNNSKTAPYNNVPSFSANKPSRGCSGGGGGGGGGGGGDSLLARRCANCDTTSTPLWRNGPRGPKSLCNACGIRFKKEERRTTAATGNTVVGAAPVQTDQYGHHNSGYNNYHAATNNNNNNGTPWAHHHSTQRVPCNYPANEIRFMDDYGSGVANNVESDGAHGGVPFLSWRLNVADRASLVHDFTR
Protein: Uncharacterized protein (Q38C28)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDAEEYLHMKEREMMEEYGAVILSQRNEIEQLQRRCSELLHERSFMRASVAEDVRQFCVGHLQRQQAQQQRASGRLATSSACVQSIPVLHLLQFLHQYTSGVVPVMETEKRKRPRETGTGGICPNTPHQQRLVQRMITRRRLCIREGDSEESLQGIEVQSAEQPICADQVH
Protein: BTB/POZ domain and ankyrin repeat-containing protein NPR1 (MhNPR1) (NPR1 homolog) (E7BQV0)
Organism: Malus hupehensis (Chinese crab apple)
Function: Probable component of the salicylic acid (SA) defense signaling pathway and pathogen-induced systemic acquired resistance (SAR) (Probable). May be involved in disease resistance against fungal pathogens (Probable). May be involved in tolerance to salt and osmotic stresses.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P93002}. Nucleus {ECO:0000250|UniProtKB:P93002}. Nucleus, nuclear body {ECO:0000250|UniProtKB:P93002}. Note=Accumulation in nucleus after induction by salicylic acid (SA) treatment or after pathogen infection. {ECO:0000250|UniProtKB:P93002}.
Interaction partners:
Sequence:
MAHSAEPSSSLSFTSSPHLSNGSISHNLSCSGSESVPSLEVISLSKLSSSLEQLLIDPGCDYSDADIVVEGIPVGVHRCILASRSGFFRELFKREKGSSGKEDRPKYCMSDFLPYGDVGYEAFLVFLSYVYTGKLKPSPVEVSTCVHNVCAHDACRPAINFVVELMYAASIFQMPDLVSIFERRLLNFVGKALSDNVVPILLVAFHCQLNQLIDQCVDRVARSDIDDISLEKGLPDEVVKKIKILRRNYQQDSDPNLPPADPLHEKRIRRIHKALDSDDVELVKLLLTESNITLDEANALHYAAAYCDPKVVTEVLALGLADVNLRNSRGYTALHIAVMRKEPSIIVLLLTKGARASELTSDGQSAVSICRRLTRPKDYHSKTEQGQEANKDRICIDVLEREMRRNPMAGDASISSQIMPDDLHMELLNLENRVALARLFFPAEAKLAMVIAHAETSEFAAPSSSKGSSGNLMEVDLNETPTVQNKRLHSRLEALMKTVRLGRCYFPHCSEVLDKFIDDDLPHLFYLEPGSSDEQKVKRRRFMELKEEVQKAFDKDKAECNLSGLSSSSSTTSPEKIGANQKVREP
Protein: Ubiquitin carboxyl-terminal hydrolase Usp2 (EC 3.4.19.12) (Ubiquitin specific protease 2) (Q8IQ27)
Organism: Drosophila melanogaster (Fruit fly)
Function: Hydrolase that deubiquitinates polyubiquitinated target proteins. Required for preventing the activation of the Toll signaling cascades under unchallenged conditions. Essential for bodily calcium homeostasis.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase
- Ubiquitin carboxyl-terminal hydrolase
- FI19924p1
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-ribosomal protein eL40 fusion protein
- ubiquitinyl hydrolase 1
- GH17761p
- Charged multivesicular body protein 4
Sequence:
MMLDIKKTRGFHKIPQASKLQSTTKTSSVVATSASSQNEVPSPGGSAGSKVGATNPVRAANQRFFLVSSYKDPTFLKAECDLAHAHVTTSKVKTTLQPHRRSRAGEDSRNNNYNTSRAPTLINMRRPSLFNGNQQPTTTNSTTINNTTSRNTTSNTSNGVLKYSVRSTTATATSTSTRNYGKLKPLNNNQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQQQQHDDISFIDSDDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQQQEEQPQPSSSKSASHRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDNIRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGETATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASDSTLARSGTGSSSTARSVLPPMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLSTKDQQILHEFAKLIQEMWTANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSSSRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSETRWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYERT
Protein: Lutropin-choriogonadotropic hormone receptor (Q71MM9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU361222}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU361222}.
Interaction partners:
Sequence:
MSISLLFLFYPYVLLFFGFGCGYTSSFVCPGICRCSANTIRCNNITEKSVPTSERGPRLVLKHLTMSTIASHTFDGLRRVQHIEIGQSVALETIETLAFNNLLNLNEIFIKNIRSLVHIARRTFNNLPKLRYLSISNTGITVFPDMTSIHSLEPWNQNFVLDICDNLYLLSIPVNAFVGMTTEYTAMNLFNNGIREIQDYAFNGTKINKLVLKNNRNLRVIHREAFKGAVGPRILDVSSTAIETLPSHGLNSVVELVARTAYGLKRLPPFRDLGNLQKAHLTYNSHCCALLTWDTHRDSPINAAQHNGSRPTYCDDSPSEKFPAGMVDSSDTSLLVEIHGTNEDVEDESYGGVDFQYPELGLNCQTRPTLQCTPEADAFNPCEDIAGFSFLRVAIWFINILAIIGNLTVLLIFFTSRCKLTVPRFLMCHLAFADFCIGVYLLMIAAVDLHTRGHYSEHAIDWQTGAGCSAAGFLSVFGGELSVYTLSTITLERWHTITHALQLEKRLGLAQAAGIMAGGWLICLGMAMLPLVGVSSYSRVSMCLPMDVKTPLAQAFILLLLLFNVGAFLVVCVCYVLIYLAVRNPQFPSRSADAKIAKRMAVLIFTDLLCMAPISFFAISAAFKVPLITVTNSKILLVLFFPINSCANPFLYAIFTKAFRKDVYLLLSNMGCCENKANMYRMKAYCSENLVKSSSGNKGTLICTTLRMDPLPLQSQQTKDDGDLGTI
Protein: Lysine decarboxylase-like protein (Q57VB7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Bifunctional dihydrofolate reductase-thymidylate synthase
Sequence:
MPGTDESAPYVQKIDDAQKRALVPAVKSYNNEAFLRSTQGRLIRILCEFEEPAARLRKNHIRSTVLLFGSARSMTKEEHKAAMESRVTALKSATDPQEKTRIETEMKRLRSIEWMCEWMERVTELSKRIAEFSLKEKELINASFSRLPDYFRPSLSAVNKEADVDAEADLFHDLVVTTGGGPGFMEAANKGASSVPGALTMGMGISLPFEAGLNRYVTAGLAFTFHYFFTRKFWMMYSCRAIVIAPGGFGTMDEVFELLTLRQTRKIPEFPIVLFCTKFWKTVVNWEALAEFGTISKEEVDSLCFTDSVDEAVAFIRNFFVKNGAS
Protein: TGF-beta receptor type-1 (EC 2.7.11.30) (Transforming growth factor-beta receptor type I) (Q5T7S2)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, tight junction {ECO:0000256|ARBA:ARBA00004435}. Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Cell surface {ECO:0000256|ARBA:ARBA00004241}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
Interaction partners:
Sequence:
MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM
Protein: Zinc finger protein 589 (B4DQF9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNPCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWILELGSPRSGLLPLDLNLDLWL
Protein: SKP1 component dimerisation domain-containing protein (Q389I0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Polyubiquitin, putative
- Ubiquitin, putative
- Cyclin-dependent kinases regulatory subunit
- RING-type domain-containing protein
- RING-type domain-containing protein
- COP9 signalosome complex subunit 5
- uracil phosphoribosyltransferase
- DNA 3'-5' helicase
- Cullin, putative
- Cullin, putative
Sequence:
MTYRYDYRPPNGGVEGSTVLFEPVAREHRATFSCGGGYGRNVMPEIPRPMVLPLVDYLDSFDKRFIEDWDEITTVQMVKLATLLNYEELLNLASAKLAVYLSEKSIEGLRAFLGVENDFKAEEEAELRKEYGRMSEEK
Protein: Protein CLEC16A homolog (Endosomal maturation defective protein) (Q9VEV4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for mitophagy, autophagy and endosome maturation, possibly by acting in multiple membrane trafficking pathways. Required for endosome trafficking and maturation. Functions with the class C Vps-HOPS complex member Vps16a to promote endosomal maturation into degradative late endosomes and lysosomes. In response to starvation, functions at an early stage of autophagy to promote autophagosome growth and efficient autophagy. Essential for the recruitment of lva-positive Golgi elements to autophagosomes. Likely to function by promoting membrane traffic from the Golgi complex to the developing autophagosomes. Also regulates synaptic growth at the neuromuscular junctions (NMJ) by down-regulating BMP signaling.
Subcellular location: Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:22493244}; Single-pass membrane protein {ECO:0000255}. Late endosome membrane {ECO:0000269|PubMed:20194640}; Single-pass membrane protein {ECO:0000269|PubMed:20194640}. Golgi apparatus membrane {ECO:0000269|PubMed:22493244}; Single-pass membrane protein {ECO:0000255}. Note=Under normal conditions detected in small punctate structures throughout the cytosol of fat body cells, upon induction of autophagy by starvation becomes localized to the outer membrane surface of autophagosomes. Not detected in the Golgi of Garland cells. {ECO:0000269|PubMed:22493244}.
Interaction partners:
- E3 ubiquitin-protein ligase NRDP1
- GPN-loop GTPase
Sequence:
MFRSRSWFGGPWGGRPKNRLSLEHLKYLYSILEKNTTVSESNRGLLVESLRCIAEILIWGDQHDSLVFDFFLEKNMLSYFLHIMRQKSGGSSFVCVQLLQTLNILFENIRNETSLYYLLSNNHVNSIMVHKFDFSDEDVMGYYILFLKTLSLKLNTHTIHFFYNEHTNDFPLYTEAIKFFNHPESMVRIAVRTISLNVYKVQNPSMLRFIRDKTAAPYFSNLVWFIGKHILELDTCVRTDIDHQSNQKLSNLVAEHLDHLHYLSDILLLEIKDLNAVLTEHLLHKLFVPLYIFSLTPAPPPPSLAVVTQNLAAVLNRNVDIDIQEMHNPRVSSIVALFLLSLVFLVVSHAPLVHALAWVILNGDHSVFKEGAAEILNSYVEHREVVVPGFGEPDESLEQALDTVTGQSSSSSYALSEDSGVESSSPATTELDSQADAVEAEQIKLRNITDEEKQLLQKSSSSTKADFAEMAKPFLDTVLHALDCTENDYLALLSLCLIYAMSHNRGIKNEWFEQVLAKSTRGAFSYKTALIEHLLNIITQSSQPSSRIRLITVEIALELLVTFTRPSSDDSRCITAAQQDLLFSARNQSMVVIRNFYKSEDIFLDLFEDEYNEMRKAQLNVEFLCMDSTILLPPTGTPLTGINFTRRLPCGEVEKARRAIRVYFLLRRTCQKFLNEKESLLPLTNVVNLVQVENVLDLNNSDLIACTVVAKDSSKQRRFLVIDALQLILVEPDAKLLGWGVAKFVGFLQDVEVQGDKDDSRCLHITVHRGGVTHNRTPLLSAKFLFDDHIRCMAAKQRLTKGRSKARQKKMYQIAQLIEIPGQMDSPVYAVGGTMVASSSGGSGNSSGSSSRSSHHRPMFSTANRVPGFAAVLRGSNSAGVSRTQMAPNRSIEGIRNESAGRSRRRSPSSTSGSNLRADHSDRERSPSVSMGSHSSSQSRENSQPRSTGNRSRESSPRMPRPRSEEIPLEDFQHSRNNSPHSRGNPSPASRSHTPIRVLHYDQLSGHSGSPREASLGGTNALLSQLNGLNREVLPTQSSEETSFIGSDGNEATGGSEGRRRGAIETV
Protein: Polyadenylate-binding protein (PABP) (H0Y5F5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU362004}.
Interaction partners:
Sequence:
XNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTTTQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
Protein: MICOS complex subunit (H7C1U8)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU363021}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
VYAAPKKDSPPKNSVKVDELSLYSVPEGQSKYVEEARSQLEESISQLRHYCEPYTTWCQETYSQTKPKMQSLVQWGLDSYDYLQNAPPGFFPRLGVIGFAGLIGLLLARGSKIKKLVYPPGFMGLAASLYYPQQAIVFAQVSGERLYDWGLRGYIVIEDLWKENFQKPGNVKNSPGTK
Protein: Single-stranded DNA-binding protein, mitochondrial (Mt-SSB) (MtSSB) (Q9CYR0)
Organism: Mus musculus (Mouse)
Function: Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA). In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays a crucial role during mtDNA replication by stimulating the activity of the replisome components POLG and TWNK at the replication fork. Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity. In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK. May also function in mtDNA repair.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:31298765}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:31298765}.
Interaction partners:
- DNA polymerase subunit gamma-1
- Twinkle mtDNA helicase
- Transcription factor A, mitochondrial
- Large ribosomal subunit protein bL21m
- Ribonuclease H1
- DNA-directed RNA polymerase, mitochondrial
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein bS6m
- DNA topoisomerase 3-alpha
- Small ribosomal subunit protein uS10
Sequence:
MFRRPVLQVFRQFVRHESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDSEVYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIAGKKLVVHSVSGCSLEGLA
Protein: Probable urea active transporter 2 (Q8TFG0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in active transport of urea.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- Thiamine repressible genes regulatory protein thi5
- LIN1-like protein
Sequence:
MEPILNQGYGYGFALGLGAAFALLMAIITKVLTACMGQTQNSERFSTASRSVKSGLISSSTVSAWTWPATLLSSGAWSYTYGIMGGFMYGVGGTIQITLFLFLAIQIKKKAPAAHTVSECFFIRFGKLGHCVYLFYCISTNVLVSSLLLLGGSQGFSSTTGMNTVAACFLLPLGVMVYTTLGGLKATFISDWIHTVMIYIILIVTCYTVYCSSSLIGSPAKMYDMLKEVQEVYPATGGQSYLSFKNSEMMYLTWSVMIGGLSSVFGDPGYSQRAIASDAKSVFQGYLMGGLCWWIIPMALGSSAGLACRALLLNPASVTYPNVLSSVEISSGLPVIYGMASIFGKSGAAAGLVMLFMSITSATSAELIAFSSVTTYDIFRAYINPAANGKQLVRTAHLSVIGFSLFIGALSVGFNYAGVTAGWLLTFLGIILTPEVSAVTLCLFWNKMTRFSLVVGAPFGTITGVVCWLASTYSFCDGIVNKDTVMTSKACFVGNIVSMASSPLYIVLLSYIWPDKETFDLNQFRNITVGDDIDTTELNAIVSQLKDERILKLQTYWSIGINLFILIGCYVIIPTALLGSNHDLSKSSFSGLIIVCLIWILVAAIYIILFPLWQGRKSLANVISHIIRLKAPENILLDGLTPKQSSEDVGDATSFHMDKLDKEKEKSSELKTA
Protein: Leucine-rich repeat protein (LRRP) (Q57Z09)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGRRKEKIPPPGTNKDPTTNFYSRKKWRMVFLSNVLELQGKKLIPRGMQIIGNALMKNRHVVKLELAHNDIGDAGAITLAELLRRNDTIQHLNLAQNKVTDVGGIALASAFIPNVSPNGQAGLWNRTLFTLVLSGNEMGDATLLAISKAAACHRDLMRVDLSWNKIGPLGTKCLGRSMQRNPNCTYILIGNQIGDEGTEHLCEALKRYSGKGTSSLNLLRNDVRYRGAKAVGRLIENNEYILDVSLHSNTLGLRGMQEIRHHLTSAPNRLRSLNLSNCMLGDSGAEELALLIDADLPTLERLSASDNDLTDIGGVAIVKALMTNNSLVAVNCSGNSFGAETVELTMKLVEKAKVLKQLDFTNSIESSDMRRTLAFAASDADGLSIDVGEMQEDTYEGTVQRITEHMQLTLDAEAERAKSRKGKKRGKKAAST
Protein: Angiogenic factor with G patch and FHA domains 1 (Q6PIK7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASEAPSPPRSPPPPTSPEPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDKIWPPCIRVIVIRSPVLQIGSLFIITAVNPATIGREKDMEHTLRIPEVGVSKFHAEIYFDHDLQSYVLVDQGSQNGTIVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGCERGQVRAHLRLDKKDESFVGPTLSKEEKELEGRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGRKLLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFEDVHLLQNKNKKNWDKARERFTENFPETKPQKDDPGTMPWVKGTLE
Protein: chitin synthase (EC 2.4.1.16) (C8V173)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Cell septum {ECO:0000256|ARBA:ARBA00004431}. Cell tip {ECO:0000256|ARBA:ARBA00044500}.
Interaction partners:
- UDP-N-acetylglucosamine diphosphorylase
- Chitin synthase export chaperone
- Dolichol-phosphate mannosyltransferase subunit 1
Sequence:
MSNRFSVYSTQSAGLPGGRPSNQLSTTTLLNALHAHYTSGLPYQLDAGTSVVVNNWLTAAQTGADGHNGGTFDRELAARAWEHARRRAEDGCIVLSSTHQSTPSIFEPFLTTLPLSTPSVTFTALSALKPFLRAVTAFNPSYSLYSALSANFTFTLKGDLVALTLALSTSGLNVQKGLLDIPTEPGYRAFDVFYYLLTTTSTQAEREFLALREPSAYALLNKSGTYDPPSYIPTADDAAAAEDFRAALKAIGIKGASLRNLLSVLAGLLKLGNAAGFLVDEEELEQTCEDVGDLLGVDPEILLHKCATDERELLITGIYEALVDWVISKANEAIAGELEELNANGSGEHWNDDDTVSISVVDIPRPAFGKAVALRNVFDDSLGINAEMKEDGIPAPPVGQAILNEMAAAVEQFGPDLGISTDPTKEYELDKRQGVLEKVGIDLDADSFLRQILIPVESQGIAVGKKGRFDLASTLGSSRVWHHISVHPSDDLPGALNTSAPTAAWTASAVSRQIREWRLVEWANRRLKQFDFTADFDVDEFVNRYSRLGCADGRDGVESWLMERGWTNGDAFVGHQRIWMRENAWWEAETMIDLKADEPPSTHSYFSNSMLDPHSGGTPMAESASLLGGSQSNLLHRQSAMAPSVMAKSIAPSVPPTMNMAGDYGLGSKGDDKKWDNIYYDGDAEGGDRKHLEKDEITLGRRVWTAFVWALTFWIPSFVLRYVGRMKRPDVRIAWREKVVLVLLILLFNGIVCFYIIAFGDLLCPGKDKVWNEKEVSWRSTSSNFYVSIHGYVYDITKFAKVTHGDTSPEATPSLMEPLAGKVLDAYFPPPLTRMCGNYVNDLAINLQNNDTSATEDQPLAVHKSGPRNRPDTTTKLHNITWYEQDFLPKINEYYKGKLVWSKDTVKKQAESSSERKWVIAHNKIYDLTDYFYTLDMMNSESSYDWLPSAITDLVKNNPGQDVSDKWPLMSSPFREAQSCLDYVFYKGDTDFRDGPRCTVNNWILLAFTILICAVVLVKFLAALQLGSKRRPAPQDKFVICMVPAYTEGEDSLRKGLDSLTALQYDNKRKLIFVICDGMIVGGGNDRPTPKIVLDILGVDPKIDPPALPVKSIGQGNEQLNYGKVYSGLYEYEGNVVPYVVVVKVGKESEQNKSKPGNRGKRDSQVLLLNFLSRVHHRAPMSPLELEVFHQINNVIGVDPELYEYCLMVDADTSVREDSLNRLVAACANDARIAGICGETSLQNEERSWWTMIQVYEYFISHHLAKAFESLFGSVTCLPGCFCMYRLRTADRGRPLIISEKLLEEYSDNNVDTLHKKNLLALGEDRYLTTLMTKHFPTMSYKFIPDAFASTAAPETWSVLLSQRRRWINSTIHNLVELAALKDLCGFCCFSMRFVVMVDLLGTIILPATCVYLGYLIYRVASDTGPFPMISIVMLAGIYGLQAIIFIIKRQWQHIGWMIIYLCAYPIYSFILPLYSFWKQDDFSWGNTRVVIEEKGSKRIVAVEDEQFDPRSIPLQRWDDYALANNLPGRRGDYAVGQEKAFYGGRYMDDTAMEMDDMHSQYSSVKPASTILTGFPGQGRHSYMPPQSPAPFGGNVPGNRNSHFSTFSRYTDQPLQSNSHLQTRHMSMGNLSQLESSGMTNRHSVGMMQSTDNLLRPNSRSPVGFNSRPASAFDFRAGMNGPDEGAITEAIRSCLAEVDLDTVTKKQVRALVEQRLQTTLVGDKRTFLDRQIDNELANM
Protein: Nucleolar protein dnt1 (O74354)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Negatively regulates the septation initiation network (SIN) pathway, independently of the cdc14 phosphatase clp1. May also have a role in silencing rDNA transcription. Required for maintaining the exclusive nucleolus localization of nuc1.
Subcellular location: Cytoplasm. Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Note=In late anaphase, localizes to the ends of the mitotic spindle.
Interaction partners:
- Non-structural maintenance of chromosome element 4
- Non-structural maintenance of chromosomes element 1
- E3 SUMO-protein ligase nse2
Sequence:
MRTTLRLHIIKDGEQDNQFMILFDPSSSISLLKEKVQETYKSLYPFESNINIRNIKNEESYDIPNEYLVGEIFPTNSKVIVESFSSPLKKLDGTMINFKEKNIQHDLDGVENDFATVQSASNGVHAINGKRTHPDESENPRKLPKKNFVEAIDANSPGFVYRPTSIRDRAYSISSNHDNESTLTEGIALKEIESPDKDRKADGIVNLSVTQEEDDNHQSFNSSLTPSQPTTYNRANFFSINDASSDSSSDAPLRTLSSPSRLRMKDNDRKYLVEHSPAALIKESETIDGIDDKSLRSSTREVSVESPNEDSVNDDSSSDVSDEKETEAKHEIRAPAIIVRETSSHPSTAVPSENDTTESENDTLSESSTTSISSSPSENSDTSDDLTKVDSPNKSLVNDNVSAKHDKESENGKSKFPPPSQTLVTTSTISAAGNEPSDEIGSENDSDSDSDSDSSVPLSQLQKKSQQRNSVSHEIQNRGTKGSPKEPKAKPSTERPETHRTLSYSRLSELSKTFSPEIREPSLTKKTAVSMQESKEEGRSDESSESEESGSSSDESDNSEKEDRSNPIPVEKRASTVLNTKKKRKAKRNSALAGLAALV
Protein: Oxidoreductase, putative (EC 1.6.5.5) (Q582N8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKTMRAVTLKAYGAVNMLGIGQVPEPAFSRPNDVLIKVVAAGVNRADISQRRGHYPPPPGVSELLGLEVSGVVLRVGSNVKRFGEGDRVMALLAGGGYADLVVAHEGSVMKIPDEYSFVEAAAIPEGFLTAWQLLRRHGSLKKGQCVLVHAGASGVGTSLMQLAGKYFGAKVVATCSEGKVDFCKKFADIVVDRSPDEMGRCFCHKVKSAVGDDAVNLVVDPVVGGSYLNEDGIVLAQDGKIVVIALMGGSKVELNISTLLRKRGTIVFSKLRDQTDEYKASLVEEFEREVIPYLKDRIITPIVQRTFAMEDVAEAHVFMEGNMTNGKVILTMCDSTGE
Protein: Uncharacterized protein, isoform F (Q9VYJ6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSHTHTAIDFWKKFLGLYRSMPELWLVRSKLYRDRQLKLESYSRLLELLRTTDSYANIHTLKRKINNFRTSYRRELRKVLDSGNTYKPTLWYFKELDFLYELETGELQLEGIVAADRDLVRNSKVLQNESNKTITFGAQLAEQEVSMSFIVKREIEVDENITEDMQQLETEDVDIMSDAFPHEEDMLRLDAVGDGDVEPEPEPDNDPELDNMDDHVDDYRNNSSAGSIKNNGYQQHTVSSHQQHNGESQTSDKSGRRIRNRRRRSSNDTDYVEAARKRRNVETSNRDRDWHRERDRERDRKHESDSEYECELIGKRMASHFRRMRPDQRLFAERIISEVLVYGRMNRLSFETQFSMGHK