wanglab/gogpt-training-data huggingface dataset:
Protein: Polyadenylate-binding protein 3 (AtPabN2) (AtPabN3) (Poly(A)-binding protein 3) (Nuclear poly(A)-binding protein 3) (Poly(A)-binding protein III) (PABIII) (Q9LX90)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length. Increases the affinity of poly(A) polymerase for RNA. Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation.
Subcellular location: Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:23334891}. Cytoplasm {ECO:0000250|UniProtKB:Q7KNF2}. Note=Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus. {ECO:0000250|UniProtKB:Q7KNF2}.
Interaction partners:
- Cleavage stimulating factor 64
- Polyadenylate-binding protein 2
- Polyadenylate-binding protein 1
- FIP1[V]-like protein
- Nuclear poly
- SAP domain-containing protein
- Polyadenylation and cleavage factor homolog 5
- Polyadenylation and cleavage factor homolog 1
- Cleavage stimulation factor subunit 50
- Regulator of nonsense transcripts UPF2
Sequence:
MEEEEHEVYGGEIPEVGDTDVPDPDIDMSAADEDAVTELAEMKRRLKEMEEEAAALREMQAKVEKEMGATQDPASMAANQEGKEEVDARSVYVGNVDYACTPEEVQLHFQTCGTVNRVTILMDKFGQPKGFAYVEFVEVEAVQEALQLNESELHGRQLKVSPKRTNVPGMKQYHPGRFNPSMGYRFRRPFVPPYFYSPYGYGKAPRFRRPMRYMPYQ
Protein: PPE family immunomodulator PPE68 (P9WHW9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Plays a major role in RD1-associated pathogenesis, and may contribute to the establishment and maintenance of M.tuberculosis infection. Together with PE35, stimulates the secretion of IL-10 and MCP-1 from human macrophages, via the interaction with human Toll-like receptor 2 (TLR2). Stimulates high levels of gamma interferon secretion in peripheral blood mononuclear cells isolated from tuberculosis patients, as well as from healthy tuberculin purified protein derivative-positive donors. Does not interfere with the secretion and immunogenicity of EsxA (ESAT-6) and EsxB (CFP-10).
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:14573626, ECO:0000269|PubMed:15039340}. Cell membrane {ECO:0000269|PubMed:14573626, ECO:0000269|PubMed:15039340}. Cell surface {ECO:0000269|PubMed:24467650}. Note=Detected predominantly in the membrane and cell wall fractions. {ECO:0000269|PubMed:14573626, ECO:0000269|PubMed:15039340}.
Interaction partners:
- PE family immunomodulator PE35
- ESAT-6-like protein EsxB
- ESX-1 secretion-associated protein EspG1
- ESX-1 secretion-associated protein EspJ
- 6 kDa early secretory antigenic target
- ESX-1 secretion-associated protein EspE
- ESX-1 secretion system protein EccCb1
- ESX-1 secretion-associated protein EspI
- ESX-1 secretion system protein EccA1
- ESX-1 secretion system ATPase EccB1
Sequence:
MLWHAMPPELNTARLMAGAGPAPMLAAAAGWQTLSAALDAQAVELTARLNSLGEAWTGGGSDKALAAATPMVVWLQTASTQAKTRAMQATAQAAAYTQAMATTPSLPEIAANHITQAVLTATNFFGINTIPIALTEMDYFIRMWNQAALAMEVYQAETAVNTLFEKLEPMASILDPGASQSTTNPIFGMPSPGSSTPVGQLPPAATQTLGQLGEMSGPMQQLTQPLQQVTSLFSQVGGTGGGNPADEEAAQMGLLGTSPLSNHPLAGGSGPSAGAGLLRAESLPGAGGSLTRTPLMSQLIEKPVAPSVMPAAAAGSSATGGAAPVGAGAMGQGAQSGGSTRPGLVAPAPLAQEREEDDEDDWDEEDDW
Protein: Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Chemokine (C-X-C motif) ligand 8) (Emoctakin) (Granulocyte chemotactic protein 1) (GCP-1) (Monocyte-derived neutrophil chemotactic factor) (MDNCF) (Monocyte-derived neutrophil-activating peptide) (MONAP) (Neutrophil-activating protein 1) (NAP-1) (Protein 3-10C) (T-cell chemotactic factor) [Cleaved into: MDNCF-a (GCP/IL-8 protein IV) (IL8/NAP1 form I); Interleukin-8 ((Ala-IL-8)77) (GCP/IL-8 protein II) (IL-8(1-77)) (IL8/NAP1 form II) (MDNCF-b); IL-8(5-77); IL-8(6-77) ((Ser-IL-8)72) (GCP/IL-8 protein I) (IL8/NAP1 form III) (Lymphocyte-derived neutrophil-activating factor) (LYNAP) (MDNCF-c) (Neutrophil-activating factor) (NAF); IL-8(7-77) (GCP/IL-8 protein V) (IL8/NAP1 form IV); IL-8(8-77) (GCP/IL-8 protein VI) (IL8/NAP1 form V); IL-8(9-77) (GCP/IL-8 protein III) (IL8/NAP1 form VI)] (P10145)
Organism: Homo sapiens (Human)
Function: Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection. Also plays an important role in neutrophil activation. Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells. G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
Subcellular location: Secreted.
Interaction partners:
- C-X-C chemokine receptor type 2
- C-C motif chemokine 2
- C-X-C chemokine receptor type 1
- Platelet factor 4
- Atypical chemokine receptor 1
- C-C motif chemokine 8
- C-C chemokine receptor type 2
- Interleukin-4
- C-X-C chemokine receptor type 4
- C-X-C chemokine receptor type 3
Sequence:
MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
Protein: Eukaryotic translation initiation factor 4C (F4K1D3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Eukaryotic translation initiation factor 3 subunit A
- Small ribosomal subunit protein uS10y
- At5g54760
- AT5g54940/MBG8_21
- Protein translation factor SUI1 homolog 1
- Eukaryotic translation initiation factor 3 subunit E
- Protein translation factor SUI1 homolog 2
- Eukaryotic translation initiation factor 2 subunit alpha homolog
- Eukaryotic translation initiation factor 3 subunit G
Sequence:
MPKNKGKGGKNRKRGKNEADDEKRELIFKEDGQEYAQVLRMLGNGRCDVMCIDGVKRLCHIRGKMHKKVWIAAGDIILVGLRDYQDDKADVILKYMSDEARLLKAYGELPENTRLNEGIVGDLDDDDDVFVFVVGSLFQLVLSNLRYISS
Protein: Btbd2 protein (Q5XJI1)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
DVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKHLRADNAFMLLTQARLFDEPQLASLCLESIDKNTADAIAAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENKRKVLGKALSLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
Protein: Ornithine decarboxylase, chloroplastic (EC 4.1.1.17) (Lysine decarboxylase) (EC 4.1.1.18) (Q9FPK5)
Organism: Nicotiana glutinosa (Tobacco)
Function: Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (By similarity). Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Can also use, with a lower efficiency, L-lysine as substrate to produce cadaverine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis (By similarity).
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MAGQTIIVSGLNPAAILQSTIGGGASPTAAAAENGTRKVIPLSRDALQDFMLSIITQKLQDEKQPFYVLDLGEVVSLMDQWKSSLPNIRPFYAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLALGISPDRIVFANPCKPESDIIFAAKVGVNLTTYDSEDEVYKIRKHHPKSELLPRIKPMFDGNARCPMGPKYGALPEEVEPLLRAAQAARLTVSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMSKMTVLDVGGGFTSGHQFTTAAVAVKSALKQHFDDEPELTIIAEPGRFFAETAFTLATTVIGKRVRGELREYWINDGLYGSMNCVLYDHATVNATPLAVLSNRTNVTCGGSKTFPTTVFGPTCDALDTVLRDYQLPELQVNDWLVFPNMGAYTKAAGSNFNGFNTSTIVTHLAYTYPS
Protein: G2/mitotic-specific cyclin-B1 (P13350)
Organism: Xenopus laevis (African clawed frog)
Function: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:9922449}. Nucleus {ECO:0000269|PubMed:9922449}.
Interaction partners:
Sequence:
MSLRVTRNMLANAENNVKTTLAGKRVVATKPGLRPRTALGDIGNKAEVKVPTKKELKPAVKAAKKAKPVDKLLEPLKVIEENVCPKPAQVEPSSPSPMETSGCLPDELCQAFSDVLIHVKDVDADDDGNPMLCSEYVKDIYAYLRSLEDAQAVRQNYLHGQEVTGNMRAILIDWLVQVQMKFRLLQETMFMTVGIIDRFLQEHPVPKNQLQLVGVTAMFLAAKYEEMYPPEIGDFTFVTDHTYTKAQIRDMEMKILRVLKFAIGRPLPLHFLRRASKIGEVTAEQHSLAKYLMELVMVDYDMVHFTPSQIAAASSCLSLKILNAGDWTPTLHHYMAYSEEDLVPVMQHMAKNIIKVNKGLTKHLTVKNKYASSKQMKISTIPQLRSDVVVEMARPLM
Protein: Adenylate kinase (EhAK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (O96907)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P69441}.
Interaction partners:
Sequence:
MAKVFLIMLGGPGAGKGTQCANIEKHLNSSAHISTGDLLRAEIKNKTEIGLKVEDIIRNGQLVSDEIICNMVNNFIAKNEKEVIVFDGYPRAVSQLEALLKEATAETKICVINLEIPDEILIQRIVSRGKTSGRADDNTEAAAKRLAVYHAQHDEMIKAIKAKNLPYFVVDHLGGPDEVFNEIKGVFANVGLH
Protein: Equilibrative nucleotide transporter 1 (AtENT1) (Nucleoside transporter ENT1) (Q8VXY7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Nucleoside transporter involved in adenosine transport and required for nucleotide metabolism which influences growth and pollen germination. Has high affinity for adenosine when expressed in a heterologous system (yeast).
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:17151019, ECO:0000305|PubMed:21642237}; Multi-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:21642237}. Note=Tonoplast.
Interaction partners:
- Nucleoside hydrolase 3
- Purine permease 2
- Purine permease 14
- Adenine/guanine permease AZG1
- Sulfite exporter TauE/SafE family protein 4
- Uridine/cytidine kinase UKL1, chloroplastic
- Adenine/guanine permease AZG2
- Dihydropyrimidine dehydrogenase
- Ureide permease 2
- Purine permease 1
Sequence:
MTPISQRISQKSPKLRETKQIQMTTTDKSAGIVTDSEAGPETSLLLNPHEGSTKKAPSDSYHFAYIIYFTLGVGFLLPWNAFITAVDYFSYLYPSTAVDRIFAVIYMLVALVCLFVIVVFYAHKSLASFRINLGLLLFVIALLVVPVLDLVYVKGQVGLYAGFDVTSAAVALSGLGDALMQGGLIGVAGEMPERYMQAVVAGTAGSGVLVSLLRILTKAVYPQDPDGLRKSANLYFAVGIVVMVICAVFYNVAHKLPVIKFHEERKNEELIREKSEEKGSLTGLAWRTTLWDIVTKVKSHGFGIVLLYMVTLSIFPGYITEDVHSELLTDWYPILLIAAYNVFDLVGKCLTAVFMLEDEKIAVGGSIARLLFYPLFWGCLHGPMFLRTEIPVTILTCLLGLTNGYLTSVLMILAPKSVPLRHSETAGIVTVMFLVVGLASGSVIAWFWVI
Protein: Fas apoptotic inhibitory molecule 1 (rFAIM) (Q8R5H8)
Organism: Rattus norvegicus (Rat)
Function: Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MASGDDSPIFEDDESPLCSLEKMTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRREWMFKLVGKETFFVGAAKTKATINIDAISGFAYEYTLEIDGKSLKKYMENRSKTTNTWVLHLDGEELRVVLEKDTMDVWCNGQRMETAGEFVDDGTETHFSVGNHDCYIKAVSSGKRREGIIHTLIVDNREIPELTQ
Protein: Cell division control protein 73 (Q9UUE7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of nrd1 with RNA polymerase II (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized protein C13E7.08c
- RNA polymerase II-associated protein 1 homolog
- Tetratricopeptide repeat protein 1
- RNA polymerase-associated protein C651.09c
- Transcription elongation factor spt5
- FACT complex subunit spt16
- FACT complex subunit pob3
- DNA-directed RNA polymerase II subunit rpb1
- Meiotic recombination protein rec14
- Transcription elongation factor spt4
Sequence:
MDSLLLLKKSIAEKKDVKLLASSEATSKVEKIEDAQYILFDENTSPILIDEPTKFIKLENDSHFSLRSVYFAWLLRDTSIAEYIQQCSELGIQNLTFLERTDLISWLEGSSDSEHIIGLEKPKPEGSTDAATSMDVDLHKKSEEVNWLFENTRTVSNHNSVLHGIKPIDFISLRKDVLDYIHANKATASAHADEQERPAKKRNRDPIILLSPSASSLLTMHNIKKFLEEGIFVPPAEAAHAAGGGRGPELIALSHKSSNSKFGTMRFIIVEGTEKFKPDYWDRVVCVFTTGQAWQFRDYKWSEPHQLFHHVKGFLVQYVGDPPHPATHDWNVEGIFVERLRRHTDREVVSQLWDKLERWMENRWPLWNGRR
Protein: Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36) (A0A1D8PH22)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU367095}. Endosome {ECO:0000256|RuleBase:RU367095}.
Interaction partners:
- ESCRT-II subunit protein
- Vacuolar-sorting protein SNF8
- Vacuolar protein sorting-associated protein 28
- ESCRT-III subunit protein
- Ubiquitin-binding ESCRT-I subunit protein
- ESCRT-III subunit protein
- Vacuolar protein sorting-associated protein 27
- ESCRT-III subunit protein
- Vacuolar-sorting protein SNF7
- Vacuolar protein-sorting protein BRO1
Sequence:
MTTSWLNIWNPVLINRSNRPILQENEYNIYIRDNVGLYQGRQKIINHQNGRVYLTNKRLIYFDNNDSSRSIAVELKLFKNAELVAGYFRRSPKVTLYIKTENSDTTNIGGNDSGSNTKNIAIDWVCKICSFNNHLAADYKLNENELPKCTSCGIRPSKSYLMQILDSAQNNIPIREDSPASMTPEPESVSPNNDNQCPKCTFINHPALRYCEICGTELKSSNNNNNNNNTKLFKVTQSLSNVSINSNPSNLKLETGEESYTNNQPYIKLSFRKGGESKFYQEVCKVLDDIKWQILEEKGGINKNAVKLVDNSSTVNNNNTASGGGGGGIHALERLGELQRKQNEMILTTSLDDLEQLMFKYQDLIKLSTSFNKLIKQPPSTTSGVVIPALSIKKSSPLYHQELSRHISEFSINFKLTQKTSMISSQDLFAEYNRFLIRNQGFGSELVNCDDFKCAIELFEKLNLPVVVKQYVNSDIYVIRPKVNANIYGEHIVQYLKDQEHEYKLMTLQREIISGDYENINNDLYNAVNYGKTVSEISNKFNWSYNITIEELEKCVEEGSVVIDHHISGTFYYVNKFSFSETEWDDTKEIQEMRELLIKEQQEITISLRNEYDKQNMDNLVNIDPDYSFFGAGNNDKEDDLESTVTTSVSQSQTQSFNDLIGLQF
Protein: Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2 (EC 2.4.1.15) (UDP-glucose-glucosephosphate glucosyltransferase) (Q4WHW0)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process. The disaccharide trehalose serves as a storage carbohydrate that is mobilized during conidial germination. Regulates the level of trehalose as a protectant for cell integrity during thermal and oxidative stress.
Interaction partners:
- Alpha,alpha-trehalose-phosphate synthase subunit Tps2, putative
- UTP--glucose-1-phosphate uridylyltransferase
- Glycogen [starch] synthase
- Alpha,alpha-trehalose phosphate synthase subunit TPS3, putative
- Alpha-glucosidase
- glycogenin glucosyltransferase
- 1,3-beta-glucan synthase
- Alpha,alpha-trehalose phosphate synthase subunit, putative
- Trehalase
Sequence:
MSSTNGSEGDHRLLIVSNRLPITIRRSEGGKYEFSMSSGGLVTGLSGLSKTTTFQWYGWPGLEVPEDELGSVKKRLKDEFNATPVFMDDKLADRHYNGFSNSILWPLLHYHPGEIVFDEGAWDAYREANLLFAKTIVKEAQDGDLIWVQDYHLMLLPELLRAELRAAGKKANKIGFFLHTPFPSSEIYRILPVRGQLLRGVLHCDLIGFHTYDYARHFLSSCSHLLGLVTTPSSVKYEGRSVAVGAFPIGIDPDKFTDGLKSPKVQNRIASLENKFQGTKLMVSVDRLDYIKGIPQKLHALEVFLQNHPEWVGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTVDYMPIHFMHKSVSFDELIALYAASDACVVSSTRDGMNLVSFEYIATQQKRKGVLILSEFAGAAQSLNGSLVVNPWNTEELARAYHEAVSMSDEQRARKFEKLYKYISKYTSAFWGKSFVAELLQCSS
Protein: TRAF3-interacting protein 1 N-terminal domain-containing protein (Q381W6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
Interaction partners:
- Intraflagellar transport protein 57/55
- Intraflagellar transport protein A1
- Intraflagellar transport protein 80
- IFT80/172/WDR35 TPR domain-containing protein
- Uncharacterized protein
- C2H2-type domain-containing protein
- Intraflagellar transport
- Intraflagellar transport protein IFT88, putative
- Intraflagellar transport protein component, putative
- Intraflagellar transport protein 56 homolog
Sequence:
MKCRLRCLTLLYCSRYLIMPSSFSSLKINSEYTSEERDKHPRVSTNIYIYIYIYICSFVPCSSSAYFVTMATEGEVDFWSATVQAFAPLQLGNPELTPKLLKRPPFRFIHDIVTSINARFAAYDHIFRPDQLDASCIDSKEKKIEYLTTLVEYISSLLGKKVDVNVKKIVSGSEPERTNTFLQCLAMAVGYAQQDKAKKNQGAQSAESSRQQTADGKGARASTREKVLVDTTSSEQKWEDSERALEKVKLSQESTNFFEKLSAFGQFHLDEQTSVKDMGESIVAMYKELQNDTAETQPTPLPQEALETAIKRQLESVQKLQALEEENREILNKLMVLLT
Protein: Thiohydroximate-O-sulfate sulfur/sulfate-lyase (nitrile-forming) NSP1 (EC 4.8.1.5) (Jacalin-related lectin 28) (Nitrile-specifier protein 1) (AtNSP1) (Nitrile-specifier protein 3) (AtNSP3) (Q9SDM9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Responsible for constitutive and herbivore-induced simple nitrile formation. Promotes simple nitriles, but not epithionitrile or thiocyanate formation. Converts allylglucosinolate, 4-methylsulfinylbutylglucosinolate, 4-methylthiobutylglucosinolate and benzylglucosinolate to their corresponding simple nitriles in the presence of myrosinase.
Interaction partners:
- UPF0235 protein At5g63440
- Thiohydroximate-O-sulfate sulfur/sulfate-lyase
- Beta-glucosidase 23
- Scarecrow-like protein 3
- Scarecrow-like protein 4
- Scarecrow-like protein 13
- Myrosinase 4
- Scarecrow-like protein 21
- Probable cysteine protease RD21B
- Probable cysteine protease RD21C
Sequence:
MAQKLEAKGGEMGDVWDDGVYENVRKVYVGQAQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEIDADDYIVYVEGYREKVNDMTSEMITFLSIKTFKGKTSHPIEKRPGVKFVLHGGKIVGFHGRSTDVLHSLGAYVSLSSTIKLLGKWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGEFTPNQPIDKHLYVFDLETRTWSISPATGDVPHLSCLGVRMVSVGSTLYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLNTLDSYNIVDKKWFHCSTPGDSLTARGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAIGKHIVIFGGEIAMDPLAHVGPGQLTDGTFALDTETLQWERLDKFGGEEETPSSRGWTASTTATIDGKKGLVMHGGKAPTNDRFDDLFFYGIDSA
Protein: Protein BIG GRAIN 1-like B (Q9SLL2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in auxin transport. Regulator of the auxin signaling pathway.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q10R09}.
Interaction partners:
- Cytomatrix protein-like protein
- Centromere protein O
- Nucleic acid-binding protein
- Serine/Threonine-kinase
- At5g10060
- AT5g05210/K2A11_8
- ENTH/VHS family protein
- AT5g57120/MUL3_6
- Interactor of constitutive active ROPs 3
- Uncharacterized protein
Sequence:
MDPWDTYNIPLDHQHRLRNRRDHRHPSFSSTLLDQIYRSIDDSSTNSSSMRKTKHQNREDTRVSANRRDDFNRSKNLKTIEPVFFKHSSSSSSDSSGFSSSESDYFYRRSKSSPAISHPKPIRTTVERFERSPQNHRPNSSNKQEHGSFLKTKSKALKIYSDLKKVKQPISPGGRLATFLNSIFTGAGNTKKLNKINTTVTSTTAAAAAASSTTTCSSASSFSRSCLSKTPSSSEKSKRSVRFCPVNVIFDEDSSKYNNKNNKVYGNNEREYESIRHTLENRVMEENRRVIEAAKELLRSYQKKNKEVIEVSVEDDEEDDDDDALSCTSSDLFELDNLSAIGIDRYREELPVYETTRLNTNRIISR
Protein: Nuclear pore complex interacting protein family member B5 (F6SDX0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKVINTLADHHHRGTDFGGSPWLHVIIAFPTSYKVVITLWIVYLWVSLLKTIFWSRNGHDGSTDVQQRAWRSNRRRQEGLRSICMHTKKRVSSFRGNKIGLKDVITLRRHVETKVRAKIRKRKVTTKINHHDKINGKRKTARKQKMFQRAQELRRRAEDYHKCKIPPSARKALCNWVRMAAAEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSITDNSLSLKTPPECLLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSALPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTALPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAFHPQRMISRHLPSVSSLPF
Protein: MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2) (Q14168)
Organism: Homo sapiens (Human)
Function: Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19665017}. Membrane {ECO:0000269|PubMed:19665017}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9WV34}. Postsynaptic density {ECO:0000250|UniProtKB:Q9WV34}. Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. {ECO:0000250|UniProtKB:Q9WV34}.
Interaction partners:
- Protein lin-7 homolog A
- Protein lin-7 homolog C
- Tight junction-associated protein 1
- Protein lin-7 homolog B
- Brain-enriched guanylate kinase-associated protein
- Calcium/calmodulin-dependent protein kinase type II subunit alpha
- Protein PALS2
- Glutamate receptor ionotropic, NMDA 2B
- Disks large homolog 1
- Calcium/calmodulin-dependent protein kinase type II subunit delta
Sequence:
MPVAATNSETAMQQVLDNLGSLPSATGAAELDLIFLRGIMESPIVRSLAKVIMVLWFMQQNVFVPMKYMLKYFGAHERLEETKLEAVRDNNLELVQEILRDLAHVAEQSSTAAELAHILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRNASGSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGSAGLIPSQLLEEKRKAFVKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGISTKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY
Protein: Ferredoxin C 1, chloroplastic (AtFdC1) (O23344)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions (Probable). Mediates alternative electron partitioning in conditions of acceptor limitation at photosystem I. Accepts electrons from photosystem I (PSI) and is capable of electron transfer with FNR, but cannot support photoreduction of NADP(+).
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:20966083}.
Interaction partners:
- Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- Photosystem I reaction center subunit III, chloroplastic
- Assimilatory sulfite reductase
- Photosystem I reaction center subunit IV A, chloroplastic
- Ferredoxin/thioredoxin reductase subunit A
- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic
- Photosystem I reaction center subunit IV B, chloroplastic
- Ferredoxin-thioredoxin reductase subunit A1, chloroplastic
- PGR5-like protein 1B, chloroplastic
Sequence:
MATLPLPTQTSTISLPKPYLSNSFSFPLRNATLSTTTNRRNFLTTGRIIARAYKVVVEHDGKTTELEVEPDETILSKALDSGLDVPYDCNLGVCMTCPAKLVTGTVDQSGGMLSDDVVERGYTLLCASYPTSDCHIKMIPEEELLSLQLATAND