wanglab/gogpt-training-data huggingface dataset:
Protein: Midline fasciclin, isoform E (Midline fasciclin, isoform O) (RH53953p) (Q86B96)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLRLWACLLLLGSIQIQAVPFYGDSSSEEVAEFDDSSDSTHESSDNSSGYDTEFVPLEHQQQPQGRQETAATVPAQTPSGVEQKPFNVDTITTDVNSPNPAIFFQQSFPFFGNEFFNSFGGFGFGAAQEPWWKGPNVCTEKEEDETVASETEAEETVDTFGQERDGVTNVVRSPLFGQFQFSVNSCAEKPNKHVCTKIVNQNGKKKTLTLTRQCCYGYGRPRNADFTTPCEKIDIKDVEATASDMGAKQFLESARTAGELADMLGAGSGKKVTLFVPNDAAFMEYRGHHQQENNVEDAKAEASKPSIYKLHAVLGEVQLEDVPNEKLLQTELPDQKIRINSYQLPAALGLEPYRFAANCVPIEKHDKLSEQALVHTLGGVLKPLTKNLMDIIRERADMSIMRTVLEKTNLSAMLEDDKPVTIFVPTDAAFDKLEPHLRRALKEGRGCASNILKNHLLDLTFCSLATVPGAKTTAYNLLGEPLLLNRTHRAANQTGPTPIYINNLAKIIDADIMGTNGVLHVIDTILPTESALPMTSLMSQKNLTIFQRLLEASGYDDQFDDLDNVTIFAPTDKALQNTEWARMLKEQPELLNHNLDLLEFLNYHVVKPMIKTCDLSEKSLPTVAGSSVRLNLYSTHALFSDVMNRATVNCARLVHFDDESCGSVLHQVDRALAPPKNNMLKLLEANPNYSKFLELVRKANLTQLLSNDSRSLTLLVPKNDIFEELNESGEGSKPADPMALVKTHIVEDVVCCAGIIPTNWPFVRSIESISGQHLRITRDRRPKIENAGVTKCDVVATNGILHEINDIIVPRPQRQQQQRPQLIPPGAGYQPQGDFDVFF
Protein: Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) (Q61083)
Organism: Mus musculus (Mouse)
Function: Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics (By similarity).
Subcellular location: Cytoplasm. Nucleus. Note=Upon EGF stimulation, translocates into the nucleus.
Interaction partners:
- Dual specificity mitogen-activated protein kinase kinase 5
- Histone-lysine N-methyltransferase SMYD3
- Serine/threonine-protein kinase PAK 2
- Serine/threonine-protein kinase PAK 1
- Dual specificity mitogen-activated protein kinase kinase 6
- Dual specificity mitogen-activated protein kinase kinase 3
- Mitogen-activated protein kinase kinase kinase 3
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase Lyn
- Ig heavy chain V-III region J606
Sequence:
MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVVNGSTQATNLEPSPSPEDLNNTPLGAERKKRLSVVGPPNRDRSSPPPGYIPDILHQIARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFTDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSVFTPEYDDSRIRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSAEELLRHMFVHYH
Protein: Phosphomannomutase (EC 5.4.2.8) (Phosphomannomutase 2) (Phosphomannomutase type 2) (Q9VTZ6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. Required for maintaining N-linked glycoprotein glycosylation at the neuromuscular junction (NMJ) synaptomatrix, and thus acts in multiple pathways that prevent NMJ structural overgrowth, restrict synaptic bouton differentiation, and limit NMJ neurotransmission strength, in order to maintain viability, coordinate movement, and in adults ensure correct wing positioning. Acts in the NMJ trans-synaptic Wg pathway via glycosylation of synaptic Mmp2 which enables dlp/wg signaling during development.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O35621}.
Interaction partners:
- Mannose-1-phosphate guanylyltransferase catalytic subunit beta
- mannose-6-phosphate isomerase
- Mannose-1-phosphate guanylyltransferase regulatory subunit alpha
- Phosphotransferase
- Phosphotransferase
- Hexokinase type 1
- Hexokinase type 2
- Glucose-6-phosphate isomerase
- Triosephosphate isomerase
- GDP-Man:Man
Sequence:
MTTAALKRDEILLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLNGRKILNEFDFIFPENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVCPIGRQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRHIEAHYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEILEL
Protein: Mic17p (Q59WV9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MPRQRRSAPAPRQQTRSAHTAAAPAHHAPPQSYPSAHPAQPVQTQSSQPGLFGQMASTAAGVAVGSTIGHTLGAGITGLFGGSSSSAPVEAAPQQQQVAAYQQQQTQEQAKHCDADARNFTRCLEDNGGNMQICDYYLQQLKACQEASRQY
Protein: Splicesome-associated factor 61 (Splicing factor 3A subunit 3) (Q6DRK2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
METILEQQRRYHEEKERLMDAKTKEMLTKKTTLRDQINSDHRVRAMLDRYMEVSANLRDLYEDKDGMRKDELNAISGPNEFAEFYNRLKLIKEFHRKHPNEICVPMSVEFEELMKAKDNPSEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKGVEKLEYVTYLSTFDQLFDISKDRKNAEYKKYLEMLLEYLQEYTDRVKPLLDQNELYGKILAEFEKKWETGMFPGWPKETSSALTHAGAHLDLSAFSSWEELASLGLDRLKSALMALGLKCGGTLEERAQRLFSTKGKSLESLDPSLFAKNPKAKGPKKDSERNKESAFLEAQIYEYVEILGEQRQLSHENVQRKQARTGEERDEEDEEQPSESESEDEDNEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPKAFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWSKLKSQKALERWQPDTEEEYEDSSGNVVNKKTYEDLKRQGLL
Protein: Cytosolic phospholipase A2 beta (cPLA2-beta) (EC 3.1.1.4) (Lysophospholipase A1 group IVB) (EC 3.1.1.5) (Phospholipase A2 group IVB) (P0C871)
Organism: Mus musculus (Mouse)
Function: Calcium-dependent phospholipase A1 and A2 and lysophospholipase that may play a role in membrane phospholipid remodeling. Cleaves the ester bond of the fatty acyl group attached to the sn-1 or sn-2 position of phospholipids (phospholipase A1 and A2 activity, respectively), producing lysophospholipids that may be used in deacylation-reacylation cycles. The PLA1 versus PLA2 activity ratio appears to depend on the phospholipid headgroup, with mainly PLA2 activity toward anionic phospholipids such as phosphatidylglycerols. Hydrolyzes with high efficiency lysophospholipids enabling complete deacylation.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P0C869}. Mitochondrion membrane {ECO:0000250|UniProtKB:P0C869}; Peripheral membrane protein {ECO:0000250|UniProtKB:P0C869}. Early endosome membrane {ECO:0000250|UniProtKB:P0C869}; Peripheral membrane protein {ECO:0000250|UniProtKB:P0C869}. Note=Translocates to membrane vesicles in a calcium-dependent fashion. {ECO:0000250|UniProtKB:P0C869}.
Interaction partners:
- Polyunsaturated fatty acid 5-lipoxygenase
- Polyunsaturated fatty acid lipoxygenase ALOX15
- Mitogen-activated protein kinase 3
- Arachidonate 12-lipoxygenase, 12R-type
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- Phospholipase A and acyltransferase 3
- Protein kinase C alpha type
- Mitogen-activated protein kinase 1
- Polyunsaturated fatty acid lipoxygenase ALOX8
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Sequence:
MQAKVPETCLLTVRVLRASGLPSKDLVTSSDCYVTLNLPTASSHTLQTRTVKNSRNPVWNQNFHFRIHRQLKNVMELKVFDHDLVTRDDPVLSVLFDVGTLQIGTQRQSFSLGTQEKGCLEVEFRLQTLTDCEEQLISNGIVVARELSCLHVELKRTGDPKRSERKVQLVVAGACEGPQDASAGTGSFHFHYPACWEQELNVHLQDDPHEQLKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEEGPKELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDLHEDEIPVIAVMATGGGIRAMTSLYGQLAGLQELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTEVLKTQVTKSKLGALAPSQLWRYRQELAERARLGHPTCFTNLWALINEALLHDKPHEHKLSDQREALSRGQNPLPIYCALNSKEQGLSTFDFGEWCEFSPYEVGFPKYGAFISSELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSLYWSSEPSQFWDRWAQDQANLDKEQVPHLKIAEPPTMAGRIAELFTDLLTKRPLAHATHNFTRGLHFHKDYFQNSHFSAWKASKLDRLPNQLTPTEPHLCLLDVGYLINTSCPPLLQPTRDVDLILSLDYNLYGAFQQLQLLSRFCQEQGIPFPSISPSPEEQRQPQECHLFCDPAQPEAPAVLHFPLVNDSFQDYSAPGVPRTSEEKAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLRLTHYNICNNQDRLREAMHQAVQRRRKRKQFRPE
Protein: Putative F-box protein At2g16220 (Q8S8C7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MNSHFLTNDLILEVLSRLPLKSVARFHCVSKRWASMFGSPYFKELFLTRSSAKPRLLFAIVQNGVWRFFSSPRLEKSSSTLVATAEFHMKLSPNNLRIYHDNTPRYFSIGYASGLIYLYGDRYEATPLICNPNTGRYTILPKCYTYRKAFSFFGFDPIDKQYKALSMIYPSGPGHSKILTFGDGDMNWKKIKYRVLHDIYSQGICINGVLYYLGDTSDWDNDHDVTSGNVLVCFDLRSESFTFIGLECGQLINYKGKLAVIFWDDVDDDDVKDDAIDEMHVWVLEDVEKKEWSKYAYTWTEDKLYRSQVSVVGMTASGEIVFSMRKYTSEQPFYVYYFNPERNNLRRVEIQGFEAFTKFGTVYTFVDHVEDLNVYNLKHFKSVHPPSVQPEYDESDSESEEDREIII
Protein: ADP-ribosylation factor C1 (ADP-ribosylation factor, putative) (Putative ADP-ribosylation factor) (Q9LIK1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- PX domain-containing protein EREL1
- Calcium ion-binding protein
- Bet1-like SNARE 1-1
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar sorting protein 3
- Vacuolar protein sorting-associated protein 54, chloroplastic
- Kinesin-like protein KIN-14E
- Hyperosmolality-gated Ca2+ permeable channel 4.1
- Thioredoxin H7
- DnaJ homolog subfamily C GRV2
Sequence:
MGAFMSRFWFMMFPAKEYKIVVVGLDNAGKTTTLYKLHLGEVVTTHPTVGSNVEELVYKNIRFEVWDLGGQDRLRTSWATYYRGTHAVIVVIDSTDRARISFMKDELARLLGHEDLQNSVILVFANKQDLKDAMTPAEITDALNLHSIKNHDWHIQASCAVTGEGLYDGLGWIAQKVTGKATS
Protein: RNA helicase (EC 3.6.4.13) (Q90ZF6)
Organism: Oryzias latipes (Japanese rice fish) (Japanese killifish)
Interaction partners:
Sequence:
MDDWEEEETAPSFAPVSSTDAAPQRSSWNGGARDSGNDGDSWNRSNRGRGGSAGRGGRGGRGRGFGRSDQDELNGGGGDSENGFRGRGRGGRGGFRSGGGERGRGGGYRGRDEDVFAAGDGRGAENSDAADPERPKVTYIPPSLPEDEDSIFSHYKMGINFDKYDDILVDVSGTNLPAAIMTFEEAKLCESLENNISRSGYVKPTPVQKYGLPIISAGRDLMACAQTGSGKTAAFLLPILQQLMADGVAASRFSEIQEPEAVIVAPTRELINQIYQEARKFSFGTCVRPVVVYGGVNTGYQMREIEKGCNVLCGTPGRLLDMIGRGKVGLSKVRHLVLDEADRMLDMGFEPDMRRLVGSPGMPSKEERQTLMFSATFPEDIQRLAADFLKVDYLFVAVGVVGGACTDVEQTFLQVTKFNKREQLLDLLRTIGSERTMVFVETKRQADFIAAFLCQEKVPTTSIHGDREQREREKALADFRSGKCPVLVATSVASRGLDIPDVQHVVNFDLPNTIDDYVHRIGRTGRCGNTGRAVSFYDPDVDSQLARSLVGILAKAQQEVPSWLEESAFGAHGSAAFNPSGRTFASTDSRKGGSFQDSSVKTQPAAPPAAADEDDWE
Protein: Nucleoside 2-deoxyribosyltransferase superfamily (O51387)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Interaction partners:
- Nucleoside diphosphate kinase
- Phosphoribosyl transferase domain protein
- adenosylhomocysteine nucleosidase
- adenosylhomocysteine nucleosidase
- Adenine phosphoribosyltransferase
Sequence:
MKIYLASPFFKEEEIKLRDEVLKFLEEFNLEVFSPEHHAVKKMGLLEKVDYKFANRDIREKIREVDLKELVSSDIVLALVNYVDSGTAYERGFAFAKKIPSIDFFKDKQDSDFYNLMYSDCAAAFSNYKDLREGILTFKELWIKFKGDNENFRTFFDYLKAKLGNKLKKIFTTLPANEKCGC
Protein: ORF73 (Q91LX9)
Organism: Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Interaction partners:
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCHLGDDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEEDEEEEEEDEEDDDDEDNEDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
Protein: GPI transamidase component GAA1 (P39012)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the GPI transamidase complex. Required for a terminal step of GPI anchor attachment onto proteins. Affects endocytosis.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- GPI-anchor transamidase
- GPI transamidase component GAB1
- GPI transamidase component GPI16
- GPI transamidase component GPI17
- GPI ethanolamine phosphate transferase 3
- Glycosylphosphatidylinositol anchor biosynthesis protein 11
- GPI inositol-deacylase
- N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
- GPI mannosyltransferase 3
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19
Sequence:
MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSENPRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSGLLMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLLILTNPFISITLFGLFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSFESKSVVVRSKEKQS
Protein: TORC2 complex subunit (A0A1D8PTJ4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Target of rapamycin complex subunit LST8
- Stress-activated map kinase-interacting protein 1
- Serine/threonine-protein kinase TOR
- Ubiquitin-binding TORC1 subunit
- Uncharacterized protein
Sequence:
MSHVDLPLSSSSSIKQRSESERGRSATLNSIDIAFHSVDRNRTGQQHHENDNTLLSTTSSPHSKLGKHQSRPPRPDIKRARSATMSMLQDNTSLNSIQNTESPTWLLSDLLSNLSVFKDKNEYSIVAKANDLVMLFQQHPNLKHDVQIKAVLPRIQFMLNHPTSEVRSSCYRIIRYLIVNYESLMILVQQKLLIYIIISLSNTRNVSLIEMEQSLKLIREFLTVDKGSDLLSVGVIKTLITIVEENGDSSNNGFGNINGINDQDRIITKRIESIPESFKNACLETICEITLLNPELICHSGGFKLIINSILDKPVEIGSTCLMIVLKLLDFENSRKFVRNGFDLDSLISIYSNLSDHDDETNLDNNSTRIRKTSNYKLQKISFLISTLLKNFNGIIAYSINDFTSIKNLLMNLQKKNTKVRESILDLLLDALMIQSFPWLKNSPIGDSIMRYNELFNDGYQFKFEFKPIDDEFSKNILHHHQGLLTLILIKNGIFKHLTQIIEENRGIDIPSRSIEHKRATMLLTNLYAMANNYLPAELIGEKSLLPDLSLCASFEIFNETRHEFRPTPEYNQHVKSSIKQLNIQAKYNIDDNTFKTMVSNSKILAVKEFEDWNWQLLLTLIQGPLGNPKRFDEVLEKVPKFFKRLLSFYRPFKYRFSTVSLTKDKNSFKYINIGCQLIELFLSLDNGIKYLSKSKLLPQISEIVAQIDPFSGITSKDPILSEKRLETTASVGYLRFIGVLSSHSSGIRMLEQWQFFTLFLNIISSSTESETNNLFILTIFKYADFSIDSPFRNVLEMAIRVSNFKIRNYILKHVLPRLIKTEECRLFIIRFLVENLYCIGPSENGNGDGEIVTKSIEILYHYYQEDNFSNLDTLIQYQPSIEVLQKYRLGKKLLNNFLRFPEGFKYLERLGYLEEKFNKLTQAQDFKYLYKINSIIQYQFYPHVFHADNNSNNADNDNNDADDQLSIYFLKNLLSTEEGLNFFQFGKGKEFLHSILLSTEIIFQQISQDAKFHDIENQDDEEVKFLINAVKQNLWLIGNLALGEFGIQLLDPMYNNSLNANNNSIINIIIDNFKTCSIWQIRGICFYVLGMIASTIEGIEILDEFNWVSCVDQYGNCKRLSYPKVENLVEIFNIEMSNPYRDTRYYHIFNSIPVEVTEANSNTINDDTGDNIEELVISDNTDKPSVDENGGGGETEDDQFKISLRRKIIVLITNLQAVLSKIVNKSIRELNKLRSIYPEIFNSDTELFLEIMKLIDKANFSYHQRSFILNLFLNKDTKILENLNKK
Protein: Packaging protein UL32 (P10216)
Organism: Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Function: Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA.
Subcellular location: Host cytoplasm {ECO:0000269|PubMed:9499108}. Host nucleus {ECO:0000269|PubMed:9499108}. Note=Mainly cytoplasmic in transfected cell culture.
Interaction partners:
Sequence:
MATSPPGVLASVAVCEESPGSSWKAGAFERAYVAFDPSLLALNEALCAELLTASHVIGVPPVGTLDEDVAADVVTAPSRARGGAGDGGGSGGRGGPRNPPPDPCGEGLLDTGPFSAAAIDTFALDRPCLVCRTIELYKQTYRLSPQWVADYAFLCAKCLGAPHCAASIFVAAFEFVYVMDRHFLRTKKATLVGSFARFALTINDIHRHFFLHCCFRTDGGVPGRHAQKQPKPSPSPGAAKVQYSNYSFLAQSATRALIGTLASGGEEGAGSAAGSGTQPSLTTALMNWKDCARLLDCTEGRRGGGDSCCTRAAARNGEFETVAGDREPEESPDTWAYADLVLLLLAGTPAVWESGPQLRAAAEARRATVRQSWEAHRGARTRDVAPRFAQFTEPDAQPDLDLGPLMATVLKHGRGRGRTGGECLLCNLLLVRAYWLALRRLRASVVRYSENNTSLFDCIVPVVDQLEADPETQPGDGGRFVSLLRAAGPEAIFKHMFCDPMCAITEMEVDPWVLFGHPPATHPDELLLHKAKLACGNEFEGRVCIALRALIYTFKTYQVFVPKPTALATFVREAGALLRRHSISLLSLEHTLCTYV
Protein: Non-selective voltage-gated ion channel VDAC2 (Q9I9D1)
Organism: Gallus gallus (Chicken)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
Interaction partners:
Sequence:
MAIPPSYADLGKSARDIFNKGYGFGLVKLDVKTKSASGVEFTTSGSSNTDTGKVNGSLETKYKWAEYGLTFTEKWNTDNTLGTEIAIEDQIAKGLKLTFDTTFSPNTGKKSGKIKSAYKRECLNLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFSVGYKTGDFQLHTNVNDGSEFGGSIYQKVSDNLETAVNLAWTAGSNSTRFGIAAKYKLDSTASISAKVNNSSLVGVGYTQTLRPGVKLTLSALIDGKSINAGGHKLGLGLELEA
Protein: Uncharacterized protein (Q387T7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MIQSSKERKKHRGTLARGRSCLYCRQQSCPGTHNCAGRLHPKQPLRRGQSQKVGEAAQQRQWGGWLERTRRVIEESMQPQASTLDRKLKLLRMRRIKPGNGSFICTGNRTGESQPHATDGGERAAGHRAESTGTLTTGQGASTMTGMASSLAPSLTPTQESALLSKIESLENIVKELALQNTTQYQAISELKSSLEHCNSPPKQVTSLSQPGAEPSGGITSLLPTRECGVHAPLAMDDISRSGTFSTSYSGKREIISQAAKGIVSVQPYESLGHDAPPSLDFSDAANKVGKGGYPAQESSLQKIFDSTSDNLADETLQLRKQLRAAERKVLAWERWYVRQKQQADEKMKPLTPSRRPTKEEPPTFGPDAHRGEGRTVSEAERGPKQQEQPRVLFRAMPVGGLTSRLKRGNETRDGAMNLNAGAGNTLALDAYTLLAREAAWREVAADERASFLETFANAGHDAV
Protein: Vacuolar protein sorting 4 homolog B (Vacuolar protein sorting-associated protein 4B isoform X2) (A0A0R4IPK7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MEPTNLQKAIAIAQKASEEDQAGHFEEAIKSYHHAVKYFLHIIKREPQGKEGNQKIREKCKQYLDRVEELQDYLDKKEKAIDLANKASQEDKAENYEEALRLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCAEYLDRAEKLKEYLKKKEKAPAKPVKESQSNDKGNESDGEEDPEKKKFQNQLSGAIVMEKPNIKWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKSLFTLAREHKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGNDNEGILVLGATNIPWTLDSAIRRRFEKRIYIPLPEEHARSFMFKLNLGTTPNSLTESDFMTLGKKTDGYSGADISIIVRDALMQPVRKVQSATHFKQVRGPSRSDPNVIVDDLLTPCSPGDPQAKEMTWMEVPGEKLLEPIVSMSDMLRSLSNTKPTVNEQDLEKLKKFTEDFGQEG
Protein: Mitochondrial carrier protein (Q57XQ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MTTQDEKNRDSFLLTAGPALISGAAQAVLFNPFDRALYVRVMYRRHHFLDRRNFEHPFQGFVNAAVYRTLVAASYLFWQDSTRIFIDRYMPACFHASNSPGVNAFLIGAVAGTLNGSLLNGMQVVKYRMWSVEEKFSFFHVTRNVYEEKGLSIFFRGIVATILRDSVFGIVYEMCRNSRNVHCFFTFLGQSITQKAQYLGLASPACSHATDNNSPSPFVAASHNSGEALSTHRAEKPSVDSAVFASNLFAAMLASVFSSPFNYVRSVVYGVPSGSGPVRYIQLLQFLYLQTLFVYRSGESYTSVHATHGGSERVAMNQQDPLRTRLMERSTQRHRYPMAALRWMNSRLNIGWGSARVGLGMAISQSIFVFVQSCWKAV
Protein: No extended memory, isoform K (EC 1.-.-.-, EC 1.16.1.7) (A0A0B4LEY2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MRDRHLAKMPRGGTTTSRYEEDPDNAWNCCSWCEYLLIVILSTILLVGVLVLTLFWVMFYRDGFAWSESPKQQFNLHPILMIAGFVTLSGFSILIYRLCRCVKQIYVKLIHMFFHAVAIPCIALGFISVFASHDALHKVNFYSLHSWLGFVTMGMFVLQFVIGFFSFLVMLCCENKTYSCRSAMVPIHASLGLANFWLAIATSVTGLIEKERETVNEAGVSENKLVEHYITSAIGVTLIFIGIIVTFAVRRSNAPASAKVYVTERI
Protein: Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction) (Q8BGQ1)
Organism: Mus musculus (Mouse)
Function: Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B (By similarity). May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin.
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Early endosome {ECO:0000250|UniProtKB:Q9H9C1}. Recycling endosome {ECO:0000250|UniProtKB:Q9H9C1}. Late endosome {ECO:0000250|UniProtKB:Q9H9C1}. Note=Colocalizes in clusters with VPS33B at cytoplasmic organelles. {ECO:0000250|UniProtKB:Q9H9C1}.
Interaction partners:
- Vacuolar protein sorting-associated protein 33B
- Vacuolar protein sorting-associated protein 33A
- Vacuolar protein sorting-associated protein 45
- Vacuolar protein sorting-associated protein 16 homolog
- Vacuolar protein sorting-associated protein 11 homolog
- Rab11 family-interacting protein 5
Sequence:
MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDIVDDDDDDDLERVSWTGEPVGSISWSIKETAGSSGSTPEGREQLKGRNSFYTQLPKPPSTYSLSSFFRGRTRPGSFQSLSDALSDTPAKSYAPELGRPKGEYRDYSNDWSLSDTVQRLRRGKVCSLERFRSLQDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRAEELALSHYREHLNIQDPEKRKEFLKTCIGLPFSAEDAAHVQDHYTLLERQIIIEANDRHLESSGQTDIFRKHPRKASILNMPLVTTLFYACFYHYTESEGTFSSPINLKKTFKIPDKQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSAEEEKIDAILSSSQIRWKN
Protein: At4g11990 (Cell cycle regulated microtubule associated protein) (Q4V3B0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Flowering time control protein FY
- Cleavage stimulation factor subunit 77
- TPX2
- TPX2
- Similarity to unknown protein protein family)
- Cleavage stimulating factor 64
- FIP1[III]-like protein
- FIP1[V]-like protein
- Ribonuclease J
- Cleavage and polyadenylation specificity factor subunit 3-I
Sequence:
MEMETDTETESDEDMEMETMVFEVTEIDLEYEFDASRWFDFTREELPLESRAAELWFETAQSYPPSPFAMKLLMIEEVYDEKTESLSKSEDGEVTVEVQESDREIPQQPDVNETGNGMKSGVFRFIQGGTLSKVPNDSLHKGPTFSNRIHSDKLKYRPKSSIRPITRSSTLMKPTASVLAKQDNARLHMQVDEIKCLSSEIQSAKRQKLDGGLLRKVAEAAQETNLVHKALKKDLDKNSLHTRMKITIPQEPDFATSHRANRIRHKNDAKLEQDSTSVYRFKARPLNRKIFEAPSLPIRKNSTPKLPEFQEFRLKTSERAMQHSSAVSTSSYQGNNNHKEADKPNRTFPDGVNREPRRQRAIDIPKDDVRKDLFKARPLNKKILSSGREIGMFTKSKRETTAPLGFSFHSERTAQPDLPTDLFSKLSLSSELRPNNGSRLRFPQPEQVKGSKENRLNSFQAGNERTSKFMGNPMVQPSVVPETSRQWTSRSGKLEATVQLN
Protein: F-box only protein 27 (F-box/G-domain protein 5) (Q8NI29)
Organism: Homo sapiens (Human)
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides.
Interaction partners:
- S-phase kinase-associated protein 1
- Cullin-1
- E3 ubiquitin-protein ligase RBX1
Sequence:
MGASVSRGRAARVPAPEPEPEEALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRALVDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCGQEGLRKWMVQHGGDGWVVEENRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPELLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHVTHVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
Protein: TRAF3-interacting protein 1 (Q6PGZ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays an inhibitory role on IL13 signaling by binding to IL13RA1 and recruits TRAF3 and DISC1 to the microtubules. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8TDR0}. Cell projection, cilium {ECO:0000250|UniProtKB:Q8TDR0}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q149C2}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q149C2}. Note=Microtubules. In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip. {ECO:0000250|UniProtKB:Q8TDR0}.
Interaction partners:
- Intraflagellar transport protein 20 homolog
- Intraflagellar transport protein 172 homolog
- Intraflagellar transport protein 57 homolog
- Intraflagellar transport protein 70A
- Intraflagellar transport 80 homolog
- Intraflagellar transport 88 homolog.
- Clusterin-associated protein 1 homolog
- Intraflagellar transport 52 homolog
- Intraflagellar transport 81 homolog.
- Intraflagellar transport protein 46 homolog
Sequence:
MNESVAKKTQETLGKVIKKPPLTEKLLSKPPFRYLHDIFSEVIRTTGFMKGLYVEAEMKSDNVKDKDSKIAFLQKAIDVVMLVSGEPLAAKPARIVAGHEPEKTNELLQVIAKCCLNKLSSDEAVKRVLAGDKLDQKGKPSTSRSQDKENREGREHHRDREERKGIKESSGSREQKDPDQPKDQESKRDDKDRRRDAERSDKGRERERTKDRDRDKDKSRDREKDKTREKEREREKDRNREKERERDKDRDKKKERESHKDRERDKDREREKRREKEKDKERPRETEEKLKDRGDRKIKAAEEISKSKPQPEVASRTHQAETEEAESPSRIPRPSSAKGQRRKPKTGGQGTEQDETESEGEAEGPSAEKPIPLENGDVTDPAALQTTHSRRLPRPSSARPAAPRVKRQESYTDATPAERLGSGKTPASVILDGKKLSEDEDDEDGQFVVEEAAPPPSDVPEVESNSLELQGDDKHGGLVKKILETKKDYESSPSSKSKEQDRSLVSEASRKKERELVAREIERLRSSIQTVCRSALPLGKIMDYIQEDMDSMQNELQSWRKENKENAQALLQEQRITDGVVEPLKVELAELEQLIKDQQDKICAVKSNILKNEEKIQKMVSSISFSSQT