wanglab/gogpt-training-data huggingface dataset:
Protein: Biopterin-dependent aromatic amino acid hydroxylase family profile domain-containing protein (Tryptophan hydroxylase) (G5EED8)
Organism: Caenorhabditis elegans
Interaction partners:
- Aromatic-L-amino-acid decarboxylase
- Putative pterin-4-alpha-carbinolamine dehydratase
- Aromatic-L-amino-acid decarboxylase
- Dihydropteridine reductase
- Tryptophan 2,3-dioxygenase
- Tyrosine 3-monooxygenase
- Tyrosine decarboxylase
- Transporter
- Putative dihydrofolate reductase
- Phenylalanine-4-hydroxylase
Sequence:
MDSLFQMASAMKFQYYSKKAAGKTMSNSVSMSSDNRMEDFKRRFRRSGSLGIPFVPEEDVKQLFTPTRTVRREASIREGDEEEGVQILTIIVKSSRVSEDISKMIANLPDHTRIKHLETRDSQDGSSKTMDVLLEIELFHYGKQEAMDLMRLNGLDVHEVSSTIRPTAIKEQYTEPGSDDATTGSEWFPKSIYDLDICAKRVIMYGAGLDADHPGFKDTEYRQRRMMFAELALNYKHGEPIPRTEYTSSERKTWGIIYRKLRELHKKHACKQFLDNFELLERHCGYSENNIPQLEDICKFLKAKTGFRVRPVAGYLSARDFLAGLAYRVFFCTQYVRHHADPFYTPEPDTVHELMGHMALFADPDFAQFSQEIGLASLGASEEDLKKLATLYFFSIEFGLSSDDAADSPVKENGSNHERFKVYGAGLLSSAGELQHAVEGSATIIRFDPDRVVEQECLITTFQSAYFYTRNFEEAQQKLRMFTNNMKRPFIVRYNPYTESVEVLNNSRSIMLAVNSLRSDINLLAGALHYIL
Protein: Elongator complex protein 4 (A0A1W2PS93)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIECITKLRSYDLRRQRYFLSRHLQRKFSIKKNPYFKKPHTLKKIY
Protein: Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation) (O35242)
Organism: Mus musculus (Mouse)
Function: Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N-smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE.
Interaction partners:
- Sphingomyelin phosphodiesterase 2
- Tumor necrosis factor receptor superfamily member 1A
- Tumor necrosis factor
- Sphingomyelin phosphodiesterase 3
- Small ribosomal subunit protein RACK1
Sequence:
MAFTRKRQREQQLQLYSKERFSLLLLNLEEYYFEQHTAFHVQHQGSQEERKIRGSLKICSKSVIFEPDAISQPILKIPLRDCLKIGKHGENGANKHFAKAKSWGISLIFSQIYFIKEHNIVAPYKIERGKMEYVFELEVSGKVEDVVETLLQLHRASCLDKLGDQMAMITAILQSRLARTSFDKNRFQSVSEKLHMECKAEMVTPLVTNPGHVCITDTSLYFQPLNGYPKPVVQITLQDVRRIYKRRHGLMPLGLEVFCTDDDLCSDIYLKFYEPQDRDDLYFYIATYLEHHAAEHTAESYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIISDYSSPELDLSNPATFRDLSKPVGALNAERLERLLTRYQEMPEPRFMYGSHYSSPGYVLFYLVRIAPEYMLCLQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYDEDVSFLVNSLKLDLGKRQGGQMVDDVDLPAWASSPQDFLQKNKDALESGYVSEHLHEWIDLIFGYKQKGSEAIGAHNVFHPLTYEGGVDLNSIEDPDEKVAMLTQILEFGQTPKQLFVTPHPRRITPKFKSLSQASSYNASLTDSPVSPGEESFEDLTEESRTLAWSNIAKLQLHEQYKIHKEAVTGIAVSCNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDTTVISSSWDNNVYFYSIAFGRRQDTLMGHDDAVSKICWHNDRLYSGSWDSTVKVWSGVPAEMPGTKRHQFDLLAELEHDVSVNTINLNAVSTLLVSGTKEGMVNIWDLTTATLLHQTSCHSGTVCDAAFSPDSRHILSTGVDGCLNVIDVQTGMLISSMASEEPQRCFVWDGNSVLSGSRSGELLVWDLLGAKVSERIQGHTGAVTCMWMNEQCSSIITGGEDRQIMFWKLQY
Protein: Sporulation-specific protein 15 (Q10411)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in the initiation of spore membrane formation.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:10639340, ECO:0000269|PubMed:15654021}.
Interaction partners:
- Sporulation-specific protein 2
- Sporulation-specific protein 13
- Uncharacterized protein C1739.04c
- Spindle pole body-associated protein sad1
- Sporulation-specific protein 3
- Membrane glycoprotein spo14
- Sec14 cytosolic factor
- Syntaxin-like protein psy1
- Meiotically up-regulated gene 79 protein
- Meiotic expression up-regulated protein 14
Sequence:
MSNQSSSGSNTSDLDEESASSLVSSAASPFIDSDLETPRPNISRASTGQLAEDGDTSSQHEDSSEELKRQEVRGMRRHSDLSIDAKLGSSEGSTASSALPLTPRSPSNASWLLVRGGLLDSPILDINSVTQKSNLLNELKQVRSKLAALEHENGILSLQLSSSNKKDKNTSSVTTLTSEEDVSYFQKKLTNMESNFSAKQSEAYDLSRQLLTVTEKLDKKEKDYEKIKEDVSSIKASLAEEQASNKSLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECKTLQEKLEKCAINEEDSKLLEELKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQKESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALRFSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSYQSISNLYHELRDDHVNMQSQNNTLLESESKLKTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEVNGKLSLDLKNLRSSLNVAISDNDQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLLHTENEELHIRLDKLTGKLKIEESKSSDLGKKLTARQEEISNLKEENMSQSQAITSVKSKLDETLSKSSKLEADIEHLKNKVSEVEVERNALLASNERLMDDLKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSEYENLLLISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRKKSKKQHDLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQDRDDLLDSLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSRLTVLSLENYLDAFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHEHDDWLIQRGDLEKALKDSEKNFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEIRLKEDVLKEKESLIISLEESLSNQRQKESSLLDAKNELEHMLDDTSRKNSSLMEKIESINSSLDDKSFELASAVEKLGALQKLHSESLSLMENIKSQLQEAKEKIQVDESTIQELDHEITASKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLADLEYHKSQVESELGRSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRTLRSLEDSVASLQKECKIKSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDRCEHLSGKLKKLHSQLEEQHETFFRAEQQRMTQLGFLKETVKKQEKLLKKLNLRQEQLIPRSSILVYESYIRDIEKEIIVLQERLNGIELSQQLPKGYFGYFFKTNRVEMEVLDSFKQQVAKLQFLAGAEFIVKFKEDLEKCAAEEKEKQATFDNYSEKVENLGKSIEALYFALNREISFRKSLALSKSAYHNLLVRDSPKFNPDSQITYSIPVTNTKQSLLRSAILCVISLQRLRLLGQRHSFCEEVIENLSCV
Protein: Interferon regulatory factor 8 (H3BT31)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFF
Protein: Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1) (Osmotic stress/abscisic acid-activated protein kinase 7) (RK4 kinase) (stress-activated protein kinase 7) (OsSAPK7) (Q7XQP4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May play a role in signal transduction of hyperosmotic response.
Subcellular location: Cytoplasm {ECO:0000269|Ref.2}. Nucleus {ECO:0000269|Ref.2}.
Interaction partners:
- Probable protein phosphatase 2C 6
- Probable protein phosphatase 2C 8
- Probable protein phosphatase 2C 68
- bZIP transcription factor ABI5 homolog
- protein-serine/threonine phosphatase
- Probable protein phosphatase 2C 30
- bZIP transcription factor TRAB1
- bZIP transcription factor 23
- Os09g0456200 protein
- Os01g0813100 protein
Sequence:
MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIFVANPAKRITIREIRNHPWFLKNLPRELTEAAQAMYYKKDNSAPTYSVQSVEEIMKIVEEARTPPRSSTPVAGFGWQEEDEQEDNSKKPEEEQEEEEDAEDEYDKQVKQVHASGEFQLS
Protein: Signal transducer and activator of transcription 4 (O70428)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
QLEIKFLEQVDQFYDDNFPMEIRHLLAQWIETQDWEVASNNETMATILLQNLLIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRILAAANMPIQGPLEKSLQSSSVSERQRNVEHKVAAIKN
Protein: Sororin-like protein 1 (O14291)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:38830897}.
Interaction partners:
Sequence:
MDSDDSFVKTAHVIETSTPENKKLSHRFKSVEIVPPSSSNDDPFGFSSTKGIRLSSINSNDLVNTLSKGFNETSNMSYNRILPSSPPTLEIGEIDYNEALQIRSADENQQSVPTVSIASPSTPELPPSSSPLLPPNGSESSSPIPLSLLSTSSLQQRKITPSNLSNTSKPMDSKQLERLIPVPHGHHLTRLRKKRRRDDDIDLSGLYETKSSSPPAIHSDEDPSYSDSIARSPVKSAFNLRKRRKGVKEKKILKTYHSQDKDTASDNDNNTGSSDEENDNLKELTPGKKEYLKSIKKYFQDVDDYQLHVVNEG
Protein: Tail protein (Q38003)
Organism: Streptococcus phage Cp-1 (Bacteriophage Cp-1)
Interaction partners:
Sequence:
MQESTKIWLYAKSPFKNDYANVINFETRESMEDFFTKKNPHIEIVYEYDKFQYTQRNGSIVVSGRVEKYENVTYMRFINNGRTYYAFVFDVLYINEDATRIIYEVDVWNTYQHELKALNVIGQVEQQTLPNELWALKDSQQGFSVGTKYATRAGEVGIDTEWLVVVAKPTIKMTTKANRPVNMSYSGMQKTFKYFFIPVNLKSGASSRLFFRAKSMIAFTLKTCISTFSD
Protein: Polycystin family receptor for egg jelly (PKD and REJ homolog) (Polycystic kidney disease and receptor for egg jelly-related protein) (Q9NTG1)
Organism: Homo sapiens (Human)
Function: May have a central role in fertilization. May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9Z0T6}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:Q9Z0T6}; Multi-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000269|PubMed:31429579}.
Interaction partners:
- Zona pellucida sperm-binding protein 3
Sequence:
MRPGPALLLLGVGLSLSVGRLPLPPVPRGAQAAVSGAPGGLLRGAPGLGVRGGRALLSLRPSAVRAGGAVLSGRGSLCFPHGGTGRRWYCLDLRVLLSAQRLPWPAAPALALVDLQLSARGGRLSLTWSVRLPRSPGRLAWAFRLRLLGPGAARPASPAARVSPRSAAPGPRPQQGFVARTECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRINTDQKGAPVRLSMQAEATINASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLPQLEIRNSPLFIHIPNNSLQWGVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVMLGDANITANFTEQLILDGSTSSDPDADSPLQGLQFFWYCTTDPRNYGGDRIILGSKEVCHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVIRKDSRTAFSDKRVHVLQGPKAIAHITCIENCERNFIVSDRFSLFLNCTNCASRDFYKWSILSSSGGEMLFDWMGETVTGRNGAYLSIKAFAFRHFLEAEFSISLYLACWSGVTSVFRHSFIINHGPQIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIVSDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNMKTELPLRDDRVNLRKHLIDQSFLLPVSTLVEIGQVVMTITKLTQKPSEFTWDAQKRATMRVWQANQALQEYQQKDKRFRSEQIEIVSTGILMSLSNILKMTSPHQVVKDPFYVIESLSDTILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFRNEKHCRNCFYPTLNVSSVPGLSANGPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMTGVADNGSVLEITPDVAEVYLVRKNLTFAAFNLTVGPNSEVDGSLKKTTGGFSFQVDSTVLREVLVHIVTEVMVLFTVLVYTGSQITPTALVATFLVPHDIPPFASQSALFDPACTVKKARVVCLPVSLLQLIAQHSHSPHCTVSIVLQAPRFVMKLNDKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMRSMMIGIESVLITIPVQLLITFLFTCSQRKPQADLKEVSPQKHPLMSEASEHWEEYLRKWHAYETAKVHPREVAKPASKGKPRLPKASPKATSKPKHRHRKAQIKTPETLGPNTNSNNNIEDDQDVHSEQHPSQKDLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMRQVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKPQGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKAKDEPEFFIDMLYGQPEKNSHRYLGLKTRNINGKKMVYLVV
Protein: threonine--tRNA ligase (EC 6.1.1.3) (Threonyl-tRNA synthetase) (A8KC60)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MADESVTDQLKELKMEEKKNTKDGGKKKNKNAAGDSGGKTELSPPPQYIDERLSIYNKLKEEHDALLAEKAAKESKPIKITLPDGKVVDGESWKTTPYQVACGISQGLADNTVISKVNNGVWDLDRPLEEDCSLVFLKFDDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLDNEGVSSNDFPCLENLCKKIIKEKQPFERLEVKKETLLEMFKYNKFKCRILNEKVTTPTTTVYRCGPLIDLCRGPHVRHTGKIKAMKIHKNSSTYWEGKADMESLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKLGREQDLFFFHDLSPGSCFFLPKGAYIYNTLIEFIRSEYRKRGFQEVVTPNIYNSKLWQTSGHWQHYSENMFSFEVEKEIFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCSMDQIESEIKGCLDFLRTVYDVFGFTFKLNLSTRPEKFLGEPEVWDQAEKQLENSLNDFGEKWVLNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTFVSHDGDDKKRPVIIHRAILGSVERMIAILTENYGGKWPLWLSPRQVMVVPIGPTCDEYAQRVQKEFHKVGLMTDVDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKSSDTVNVRTRDNKVHGERSLTDCMERLKQLKASRTRNAEEEF
Protein: Epididymis luminal protein 55 (V9HWB6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLRAPSVALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK
Protein: CD59 glycoprotein isoform X1 (Potassium inwardly rectifying channel subfamily J member 11,-like) (E7F8K3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
- Kir6.3 protein
- ATP-sensitive inward rectifier potassium channel 8
- Ubiquitin-conjugating enzyme E2Ka
- ATP-sensitive inward rectifier potassium channel 11
- protein phosphatase 1, regulatory
Sequence:
MKLSLGLFLLVCCMTLSLGNKHYGMRFSSAGSSLRCYKCEDYAGGRCSVQQPCSYEDACLHLHEKGGKTIRRCIRYTDCDNSRLSQQFPSISEYTYRCCNTDLCNGGPLTTAGSLFLSLLAVFTGLFHCMIC
Protein: AtlA (Autolysin A) (O30554)
Organism: Neisseria gonorrhoeae
Interaction partners:
Sequence:
MWRGISSGRHVRGNYVLKASTAHNQAELERYVHNPQVRAFLDFIAASEGVKHGYQTAIGNYRITDFSRHPGNSVRRSFTRTDGSRSTSDASGRYQFMGYTWKGLAKQYGFTDFSPATQDKAAVALILAKKGAMEAILNGDYEQAVMKLGGIWASFPTAPNEYRQHKRSWGFVHNFFRQRGF
Protein: Uncharacterized protein (Q582S7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLSQFDDNPLVEEREGELQGLSSEVTNAQKKRPREDNLQEPDSKHEVATHEPPEKQPRLEEDAEGCTEGEPFIGYSVEAVDDVDEADETYGELLNRVAALESGRRNSACAQRFQMTLKTAEREALRGCMSHLRALLAGLQGKRTKPTTAAAAAAPSSSPTTTATNPPYCPLQPSQCAQMMELYGNAERLARLGTRSHWLKCAGARTRAMNPEGCSWTPPLATETSGGTVPTKQFVDKGRRRFEEMEKALQKVPPELIGPAAPALSALSNKLQQVCETSDALCSRQHEIERCVPELMARWNQYSLWGAERSLLIAEEQMIDHLAAQNPTAAEEQLLSQQQRQQKRLHQAEIAVATLLASASDVKVPKVSQGFLRSAMQRYEDLQKLRSALYRELVSLRKLLKEKLLLSTHSVVGGECFFLGARAAEEGRRCLLQHSCAALCQRSAELNKHLVTEVLRGSMACPPSPEQEEKLLQYEVKSATQHASIVTLIAENARLQQRIKGVSLVQLLATSGNGKFASIAGKLRSTTTSVVGKHTTHQEGNVRVNEEAVREEGEEVESAANNIEVEEPDILGHFVDVFARSTEELVKSINTRLWDLSNLYKDERQLQRDVAFLVRLTVAGERLLHGKVGVPLMSGYAEDITILLEEARLRLVDTKRSVRQLPSLRTLCESLQSQSASHAEQLLKEHTAAEAVRAQLLEDLEWCKQQSPEMAGGQLVVARKELQKLRVSLETITKQGHDPTPLELETQKAGEQLAQLRQQLEKLQEEVDLAEHQLQCLEDDEVVDAQEDVCEENGGIAEEEEVEEGQEAEKVEEGEEEEVEEGQGLAEEYEVGEQREENHGEMEERGNGDGGDGRDGDEVVP
Protein: Probable acyl-coenzyme A oxidase acox-1.5 (AOX 1.5) (Acyl-CoA oxidase 1.5) (EC 1.3.3.-) (P34355)
Organism: Caenorhabditis elegans
Function: Involved in the first step of peroxisomal beta-oxidation by catalyzing the desaturation of fatty acid-derived side chains.
Subcellular location: Peroxisome {ECO:0000250|UniProtKB:O62140}.
Interaction partners:
- MaoC-like domain-containing protein
- SCP2 domain-containing protein
- Non-specific lipid-transfer protein-like 2
- Acetyl-CoA C-acetyltransferase
- Acetyl-coenzyme A synthetase
- Enoyl-CoA Hydratase
- Probable 3-ketoacyl-CoA thiolase
- Acetyl-CoA acetyltransferase homolog, mitochondrial
- 3-ketoacyl-CoA thiolase
- Enoyl-CoA Hydratase
Sequence:
MPLNKLIQDGDNQDLTDERFKATFDTDALAAVFHGGEDALKRIRELRDEVTKRWHLFDALPGAHRTRAERMEDVSRKLKNLMESVGEFADFTNNLDMLVIIRDVMGIEGFPLALHNLMFVPTIQNQADDEQTEWWLMDALQGKIIGTYAQTELGHGTNLGAIETTATYDKLTEEFIIHTPTTTATKWWPGGLGTSCTHVVLVANLIIDTKNYGLHPFFVPIRDRNSYSVMSGVRVGDIGTKMGVNCVDNGFLAFDNYRIPRRNMLMKHSKVSKEGLYTAPSHPKVGYTTMLYMRSEMIYHQAYYLAMAMAISIRYSAVRRQGEIKPGTQEVQILDYQTQQYRIFPGLARCFAFNTAAATVRQMTENCIKQLSHGNSDVLADLHALSCGLKAVVTHQASQSIDQARQACGGHGYSDASYLPTLYTCSVGACTYEGENMVMLLQLSKYLMKAAAKAEKGEEMAPLVAYLVKPDITETNDKFAKMLSHFEHIARHRVMHAYRQMIEEEKQGIERDYAFANHSVDWTKAARAHTKLFIARGFVKSVQEVSDEAVHDVLTTLAELYLSYELIEMSADLTANGYLSESDVQQIRHQIYDSMRKTRRNAVSIVDSFDICDRELRSVLGRRDGHVYENLYKWAQMSPLNERNLPHVEKYLKPMTSKL
Protein: Carbohydrate-binding domain-containing protein (Q55C03)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Large ribosomal subunit protein uL23m
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein uL3m
Sequence:
MKNNYSLLLLLLFINIFFISFGSSMNQVTLDETTNYIFQWELIENDEILIILSANIKTWLGIGWGNEINGMSNADYAIGIFDNKGNLNMSDMVVTPTQKMNKPSYDTKVGGTNDILTSYGYQTSDYTYIKFTRKLVTGDLVGDRDLFVDGRMTTLIWARGSSQNLTYHGQNNRGEISIDLSGANKSVQVNNSKDVYLYWHISLMLGSFLVLMPFGIFVARYMRHYHYWFPLHYLLLGTAFTFSIVAFILAFMMTSDRKFSKHLLHAWFGLFTIILMCLVVIGGVMSHLLWKPDRKKTPIFPDIIHAFLARLTYLIALVSIWTGLNTFEIPKQFSIVLGFVVSLFFGLVIFLEIYRKRYPNSVGDHGFDKKEIKLQERNSSTVDSTININN
Protein: Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (C9K0M0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAAL
Protein: Thioredoxin H5 (AtTrxh5) (Protein LOCUS OF INSENSITIVITY TO VICTORIN 1) (Thioredoxin 5) (AtTRX5) (Q39241)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Thiol-disulfide oxidoreductase involved in response to pathogens and oxidative stresses. Required for the response to victorin, a phytotoxin which induces programmed cell death in sensitive plants. Possesses insulin disulfide bonds reducing activity.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Thioredoxin M3, chloroplastic
- Protein RALF-like 15
- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
Sequence:
MAGEGEVIACHTLEVWNEKVKDANESKKLIVIDFTASWCPPCRFIAPVFAEMAKKFTNVVFFKIDVDELQAVAQEFKVEAMPTFVFMKEGNIIDRVVGAAKDEINEKLMKHGGLVASA
Protein: Probable U6 snRNA-associated Sm-like protein LSm4 (O14352)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- LSM complex subunit lsm7
- LSM1-LSM7 complex subunit lsm1
- LSM2-LSM8 complex subunit lsm8
- LSM complex subunit lsm3
- LSM complex subunit lsm6
- Small nuclear ribonucleoprotein-associated protein B
- LSM complex subunit lsm5
- LSM complex subunit lsm2
- Small nuclear ribonucleoprotein Sm D2
- U4/U6 snRNA-associated-splicing factor prp24
Sequence:
MLPLTLLNATQGRPILVELKNGETFNGHLENCDNYMNLTLREVIRTMPDGDKFFRLPECYIRGNNIKYLRIQDEVLSQVAKQQAQQRENRGSRFRGRGQRGRGNYGHTAPNRRGRGRGGHM
Protein: Translocase of chloroplast 33, chloroplastic (AtToc33) (EC 3.6.5.-) (33 kDa chloroplast outer envelope protein) (Plastid protein import 1) (O23680)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Binds GTP, GDP, XTP, but not ATP. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast, especially during early development stages.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000269|PubMed:10998188, ECO:0000269|PubMed:12766230, ECO:0000269|PubMed:12951325}; Single-pass membrane protein {ECO:0000269|PubMed:10998188, ECO:0000269|PubMed:12766230, ECO:0000269|PubMed:12951325}. Note=May contain beta barrel transmembrane regions.
Interaction partners:
- Protein TOC75-3, chloroplastic
- Translocase of chloroplast 159, chloroplastic
- Protein TOC75-4, chloroplastic
- Protein TIC 56, chloroplastic
- Protein TIC 20-I, chloroplastic
- Ankyrin repeat domain-containing protein 2A
- Protein TIC110, chloroplastic
- Protein TIC 40, chloroplastic
- Outer envelope protein 64, chloroplastic
- Outer envelope protein 80, chloroplastic
Sequence:
MGSLVREWVGFQQFPAATQEKLIEFFGKLKQKDMNSMTVLVLGKGGVGKSSTVNSLIGEQVVRVSPFQAEGLRPVMVSRTMGGFTINIIDTPGLVEAGYVNHQALELIKGFLVNRTIDVLLYVDRLDVYRVDELDKQVVIAITQTFGKEIWCKTLLVLTHAQFSPPDELSYETFSSKRSDSLLKTIRAGSKMRKQEFEDSAIAVVYAENSGRCSKNDKDEKALPNGEAWIPNLVKAITDVATNQRKAIHVDKKMVDGSYSDDKGKKLIPLIIGAQYLIVKMIQGAIRNDIKTSGKPL
Protein: Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) (Neural zinc finger factor 1) (NZF-1) (P70475)
Organism: Rattus norvegicus (Rat)
Function: Transcription factor that plays a key role in neuronal differentiation. Acts by specifically repressing expression of non-neuronal genes during neuron differentiation (By similarity). In contrast to other transcription repressors that inhibit specific lineages, mediates repression of multiple differentiation programs (By similarity). Also represses expression of negative regulators of neurogenesis, such as members of the Notch signaling pathway, including HES1 (By similarity). The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro (By similarity). Directly binds the 5'-AAGTT-3' core motif present on the promoter of target genes and represses transcription by recruiting a multiprotein complex containing SIN3B (By similarity). The 5'-AAGTT-3' core motif is absent from the promoter of neural genes (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:9373037}. Chromosome {ECO:0000250|UniProtKB:P97500}. Note=Preferentially binds to DNA binding sites that are in an open chromatin configuration. {ECO:0000250|UniProtKB:P97500}.
Interaction partners:
- POU domain, class 3, transcription factor 2
- Achaete-scute homolog 1
- Neurogenic differentiation factor 1
- Neurogenin 2
Sequence:
MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECYESDGTEDMDDKEEDDDEEFSEDNDEQGDDDDEDEVDREDEEEIEEEDDEDDEDDDDGDDVEEEEDDDDEEEEEEEEEEENEDHQMSCTRIMQDPEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEEDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV
Protein: Alcohol acyltransferase 9 (AeAT9) (EC 2.3.1.268) (A0A068BIF1)
Organism: Actinidia eriantha (Velvet vine) (Actinidia fulvicoma var. lanata)
Function: Involved in the biosynthesis of volatile esters which confer kiwifruit flavor. Alcohol acyl transferase that can use a wide range of alcohols as substrate to produce esters. Exhibits acetyl-CoA:alcohol O-acyltransferase activity.
Interaction partners:
Sequence:
MASSVRLVKKPVLVAPVDPTPSTVLSLSSLDSQLFLRFPIEYLLVYASPHGVDRAVTAARVKAALARSLVPYYPLAGRVKTRPDSTGLDVVCQAQGAGLLEAVSDYTASDFQRAPRSVTEWRKLLLVEVFKVVPPLVVQLTWLSDGCVALGVGFSHCVIDGIGSSEFLNLFAELATGRARLSEFQPKPVWDRHLLNSAGRTNLGTHPEFGRVPDLSGFVTRFTQERLSPTSITFDKTWLKELKNIAMSTSQPGEFPYTSFEVLSGHIWRSWARSLNLPAKQVLKLLFSINIRNRVKPSLPAGYYGNAFVLGCAQTSVKDLTEKGLGYCADLVRGAKERVGDEYAREVVESVSWPRRASPDSVGVLIISQWSRLGLDRVDFGLGRPVQVGPICCDRYCLFLPVRESTESVKVMVAVPTSAVDRYEYFIRSPYS