Protein: Vitelline envelope sperm lysin receptor (Q8WR62)
Organism: Haliotis rufescens (California red abalone)
Function: Structural component of the egg vitelline envelope; forms long filaments. Functions as species-specific receptor for the sperm protein lysin; prevents fertilization by sperm from other species. Each VERL chain can bind multiple copies of the sperm protein lysin; this creates a 3 um hole in the egg vitelline envelope through which the sperm passes.
Subcellular location: Cell membrane {ECO:0000305|PubMed:9192632}; Single-pass membrane protein {ECO:0000255}. Secreted, extracellular space, extracellular matrix {ECO:0000305|PubMed:9192632}.
Interaction partners:
Sequence:
MSGMQWSFGFSCLFFLKTVWICQAFDADTPDPRVLSLDLTLVCSDDKSKQATLISYPVTFKGHVIKDMQIFCKNGWMQMTRGRGINMIRIHYPQTYTSVVPGACVFRGPYSVPTNDSIEMYNVSVALLWSDGTPTYESLECNVTKSQASNAPEPKASPTSSTPQPEAASHNQSKLIDWDVFCSQNENIPAKFISRLVAPKCLAVEKMDVDCSNGLVPITHEHGFNMMLIQYTRNKLLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTDLSIQCYMPKSPDAPKPESCLSSPPEPEASPSSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQDESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIQCYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPSSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHKFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAHKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLPIECYMPKSPVAPKPETGPSSNAPEPETYPTSSAPEKVYSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPEASPTSNAPEPQTYPTSSAPGTSPEGSATAAPGTSPEGNTTAARNAYPRKSNQTTSTEDVLDDTSNYIIKVIPHCRTRGDVALIEIITDVDLSAVAVCSNGSRHHFNSTDFVHFYLPVSYNFTPSVCAFTRSKANLFKLHIGVSWKDRLHDVTTQKKDFLITCTFDPHKSHRGPTSASSEPLIAAKEIQSHQGPQSDAEEVFLKLVDIRNETLAAAVPLSKKVRLVGEVHGSSLESGLKPVACDAVGVQQGQRYTILRDGCGDGIVFAKDIGFITEGNKAFSPVFEVFKLHGNLHLTFMCNFTLCSHSCDGSSCSNQRRTRRSMAWQDIPHVADFDSSATPSTDMATVQVALLVAVALLITQLAGLAIYVNIN