wanglab/gogpt-training-data huggingface dataset:
Protein: Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA) (Q80Z30)
Organism: Rattus norvegicus (Rat)
Function: Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases. Dephosphorylates PRKAA2 (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:11726284, ECO:0000269|PubMed:16269004}. Cytoplasm {ECO:0000269|PubMed:12807427, ECO:0000269|PubMed:16269004}. Note=A truncated form, major form, with the C-terminal part missing, is mostly found in the cytoplasm and a little in the nucleus throughout the central nervous system. Although in some large neurons, the full-length, minor form, is found in the nucleus. {ECO:0000269|PubMed:16269004}.
Interaction partners:
- Calmodulin-1
- Calcium/calmodulin-dependent protein kinase type IV
- Proline rich 11
Sequence:
MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPESEPEPEPEAELVAAEAAEASGEDPGEDAATVEAAEEGVQDQDPEPEEEAVEEEAAAEGEEEEEEEEAAAPGHSAVPPPQPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHCIPKETDGTEGTVEIETVKLARSVFSKLHEICCNWVKDFPLRRRPQIYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSPGPQINVLEDPDYLDLTQIETSKPHSTQFLPPVEMIGPGAPKKAYVNELIMEESSVTPSQPERSGAGELLVSFNLGSTGQQICRMENLSPVYSGLENEQFKSPGKRASRLYHLRHHYSKRQRGFRFNPKFYSFFSAQESSRKIGISLSSLTRSGKRNKMLRSSLPWRENSWEGYSGNMAIRKRNNISCPDLPWDYKI
Protein: TLD-domain containing nucleolar protein (Q9FKA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g62720
- LOB domain-containing protein 11
Sequence:
MGASSSTDDKESSEKREIESLAASTGALPLLKRSFSKLVDSQTNTVPFQSLKQSFGLSYDTITTEGEQKVSDLFPKLLEHLGSSLVDLFFVPDKEGLSWVEFASGYVKCCGRMSNSMSFNTLLRVYYVTAKNAGFSPKLEFESDEADCKINGSISVSELLVFLWMCWTMSWDGRSSKAAEMKGCLFLPDISHLILSAVVSCTDSESGNSLDVWETDVSGLELELPIGKFLTWALMTVPCLTECLSHFCNSRLQNVTSAEDGSGPSKSTAVDDSASKTSENTLLTCGRAWAISLTSKSTISEEILSSCFPGNSGEPNEHLLYRSYYHGKGMNRLWSNVEGYHAPILVIISASCKVEHEATSSERKWVIGAILQQGFENRDAFYGSSGNLFSISPVFHAFSSSGKEKNFAYSHLHPAGGVYDAHPKPVGIGFGGTLGNERIFIDEDFAKITVRHHAVDKTYQSGSLFPNQGYLPVEALVLDIEAWGLGGNKAREIQQKYQKREELFTNQRRKIDLKTFTNWEDSPEKMMMDMMGNPNAPRKEER
Protein: Small G protein signaling modulator 3 (RUN and TBC1 domain-containing protein 3) (Q8VCZ6)
Organism: Mus musculus (Mouse)
Function: May play a cooperative role in NF2-mediated growth suppression of cells.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q96HU1}.
Interaction partners:
Sequence:
MSGNHTPSASGPFSALTPSIWPQEILAKYSQKEESSEQPELCYDEFGFRVDKEGSEPGCSQMTGSPLVEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKKNSELSYREIIKNSSNDETIAAKQIEKDLLRTMPSNACFANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLFFYEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMRLAGSLTDVAVETQRRKHLAYLIADQGQTLGTGTTTNLSQVVRRRTQRRKSGITSLLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACLRSHRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNVTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPARREEEKQPLKEGVQDMLVKHHLFSWDIDG
Protein: CHK kinase-like domain-containing protein (Q9VBT1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGTGSKNYQAPEWLTAEFLQDVLKEHFKEEQLAVTELIVKSAQVGDQAAGFASEMHRASFNLQRGTAPKGKFSVIVKDHPKGQTGAVAHRSKLFKREILAYKEVLPRIQALLQSIGDQTKIAPTCYYTTESPEPFLILEDMQLSGFENFERGRLLNLDYVLPTIEKVAKLHACSALIAQDSPEVLEFFDEAPISRNPDRRDFLTFFPVNIRCVAEEVAHWKGYEEITEKMFNLAENVLQRALTMFESTGKDFRVFNLTDLWINNLLFHINNETKEPDDVVTLDFQLAYVGSPTIDLNYFLYGSLNENVRKVHYKYIVREYQRVLQQTLEKLNYQGHIPTLKEIHIELIKTSLMGVIGATCLTPLIFREGAGFENLEDLNSRTESGDRFRRENVENPKYRAFLQRTIKEFELSGFLDE
Protein: GH14582p (Q8MRN0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
METGDGLQQQQQQQQQQQQLQKLSKVIKMSQFPLLVSDVSLQQQQSVSGQAQQQQLKPNSAAAIAANHNYSLHPASTAIITAQATPQQANKIFLTSSNSGGGGSAGNFTIATASELQAAAAGQKLHYKELPNSNLKLNFVSSAGTGEQTQQVGATTVLLNKSQQQQQQQQHQKLKTLATTGNSQTGQGDKRVLYTSLLNVKPLQKNNSGQMQMQLGPGGLQQVLRGRLNNSAIITRTLPLGTTVNSTGGAVGPTTTTIRQLVTTNANNVSSQDGNLLSAKEVGKALTVEQVIASANNGGVVLPTSNNNNNNNGSGAGGNGGPLNSGVNATGAGGGGSTGAGVGGAGVTSTINR
Protein: Bromodomain-containing protein 2 (A8CYR7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
Sequence:
MEAAINQSFDSSVGVGLSVMAMMEQNSGKRIRKPSLLYEGFESPSLPHAPPPGPPPPLQPPVRDPSRQGRATNQLQFLHKVLVKALWRHHFAWPFHEPVDATRLNLPDYHKIIKQPMDMGTIKKRLENNYYRGASECLQDFNTMFTNCYIYNKPADDIVLMAQSLEKVFLQKVAQMPQDEIELPSPTPRGRGNKSVKARKSRGGSVTSAHQVPAVSHSAYSPSSPETPDSQFSTPPQTLLSSSGPPPSLITPPHTQPTAKVYAHALTRTHFLLSDV
Protein: Uncharacterized protein ZK632.12 (P34657)
Organism: Caenorhabditis elegans
Interaction partners:
- FYVE-type domain-containing protein
Sequence:
MVDRLVNSEVNSRRMANVEQCFGKMGEQLSVFGRVLVGEGVLVKMCRKKPKQRQFFLFNDILVYGNIVISKKRYNKQRILRLEGVQVEDLEDDGIEKHGWIIKTPAKSFAVYAATETEKREWMLHIERCVTDLLERGNKQAATAHAAVWVPDGEAVKCMVCGKTQFNLVQRRHHCRNCGRVVCGACSSRTFRIDNVHKKPVRVCDHCFDSLSSATPGQEESEPKTGNRLHHEDSSSDSEDEVNGSGRSSNESRPTFYREDVQQPAT
Protein: 40S ribosomal protein S21, putative (Q385B8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 40S ribosomal protein S14
- 40S ribosomal protein S23, putative
- 40S ribosomal protein S8
- 40S ribosomal protein S16, putative
- 40S ribosomal protein S33, putative
- Small ribosomal subunit protein uS5
- 40S ribosomal protein S26
- 40S ribosomal protein S25
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S15a, putative
Sequence:
MATIGTYNEEGVNVDLYIPRKCHATNSLITSFDHSAVQIAIANVDPNGVIDGTTTTLCIAGYLRCQGESDHAINHLAIAKGIVRIKTGKKPRAKKTKNLKVASGARTQQKGGRNAAGQTKGAAQRGAAQKPTGRPQQAQRQGGRPARTEEGNRQRQGQQRQKPQQQQQQRQQQQQQRGGDRRAPQQSGRRGPRS
Protein: Terpenoid synthase 25 (AtTPS25) (EC 4.2.3.-) (Q9LIA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in terpene biosynthesis in roots. Possesses sesquiterpene (C15) synthase activity in vitro. Does not seem to be involved in diterpene (C20) biosynthesis.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Uncharacterized protein At4g13230
- Probable alpha,alpha-trehalose-phosphate synthase 7
- Probable alpha,alpha-trehalose-phosphate synthase 11
- Dehydrodolichyl diphosphate synthase 4
- Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 2
- Putative inactive
- Probable alpha,alpha-trehalose-phosphate synthase 8
- Probable alpha,alpha-trehalose-phosphate synthase 9
Sequence:
MEASKCFGPRTLPIIHNVPLCLKTNFSLFPCRLLQSQSLSSKKSTKHYLFRVKAETSGDLESTRPLTYFSPSYWGDHFLSVSIDDSEFEALEKEIETVFKPKVRDMLMSPHSSDKERIRLIHLLISLGIAYYYENEIEEILHKAYGKLACLISDEDDLETIAIMFEVFRLYGHKMPCDVFERFKSEDGKFKESLVGDVRGLLQLYEAAHLGAPSEDIMDEALSFARYHLEPLAGTETSSNLFKHVENVLYRARYHSIEILVARQYISFYDQEEDQDETLLRFSKLNFNFCQMHYVKELKIVTRWWKELGIASKLPYSIRERNVETYLGGLGVLFEPRYSLARIFLAKLTLIMTVVDDTCDAYATLPEVQSLHDAFHRWDLRAMEELPRYMRIIYQSVFETVEDIDREMIARGKHGRLQLTIDEIKSLMIWYLGIAKWARSDQVPSFEDYMEIGTPSSALDDFASYGFIAMDDCDQKQLKEWFYSKPKIFHALNALFRIRNDIVTFEQEMSRGEVANGVNCYMKQHGVTKEAAVEELRKMERESYKIMIEEFMTSKAMPRQILVRPVNIARVMDLFYKEADGFGHPDQKLLQLIASLFLHPIPL
Protein: Fizzy and cell division cycle 20 related 1 (B1WCA1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 4
- Cell division cycle protein 27 homolog
- Anaphase-promoting complex subunit 5
- Anaphase-promoting complex subunit 7
- Mitotic spindle assembly checkpoint protein MAD2A
- Cell division cycle protein 23 homolog
- Serine/threonine-protein kinase PLK1
- Mitotic spindle assembly checkpoint protein MAD1
- G2/mitotic-specific cyclin-B1
Sequence:
MDQDYERRLLRQIIIQNENTVPCVSEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEHKGLFTYSLSSKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSVLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPALQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR
Protein: WD repeat-containing protein wdr-5.1 (Q17963)
Organism: Caenorhabditis elegans
Function: Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. Required for di- and trimethylation, particularly for the trimethylation at 'Lys-4' of histone H3. Not required for demethylation of histone H3 'Lys-27'. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, germline establishment, maintenance and function. Implicated in the epigenetic inheritance of lifespan over several generations. Acts in the germline to limit the longevity of the soma, probably by regulating a lipid metabolism pathway that signals from the germline to the intestine, thereby preventing accumulation of mono-unsaturated fatty acids. Required for RNA interference with probable antagonistic role against hpl-2 function. Plays a role in vulval cell fate specification by acting in the synthetic multivulva pathway independent of set-2. Sex determining protein required in the germline to promote the spermatogenesis to oogenesis switch during the late larval stages of development. Acts with the sex determining factor tra-1, and redundantly with wdr-5.2, to regulate fog-3 expression, which in turn determines germ cell fate. Cooperates with jmjd-3.1, egl-27 and unc-3 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development.
Subcellular location: Nucleus {ECO:0000269|PubMed:17967446, ECO:0000269|PubMed:24682813}. Note=Localized on chromatin in the nucleus. {ECO:0000269|PubMed:24682813}.
Interaction partners:
- Set1/Ash2 histone methyltransferase complex subunit ash-2
- PHD-type domain-containing protein
- Retinoblastoma-binding protein homolog 5
- Histone-lysine N-methyltransferase set-2
- JmjC domain-containing protein
- PAX-interacting protein 1
- CXXC-type zinc finger protein 1
- Dosage compensation protein dpy-30
- Lysine-specific demethylase jmjd-3.1
- WD repeat-containing protein wdr-5.3
Sequence:
MDTSENAASAAEQQPTQQIDQLTVPNAPDGGSSAPAPSTSPNSISPSNPTGTPAPGASAQTPNPNAAGASASGSANYKLMCTLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNKIHIWRSDV
Protein: Membrane-anchored junction protein (Q9D992)
Organism: Mus musculus (Mouse)
Function: Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:26548954}; Single-pass membrane protein {ECO:0000305|PubMed:26548954}. Chromosome, telomere {ECO:0000269|PubMed:26548954}. Note=Localizes to telomeres throughout meiotic prophase I and disappears in metaphase I. In leptotene spermatocytes, localizes to telomeres that localize to the nucleus inner membrane. {ECO:0000269|PubMed:26548954}.
Interaction partners:
- Telomere repeats-binding bouquet formation protein 2
- Telomere repeats-binding bouquet formation protein 1
- Protein KASH5
- SUN domain-containing protein 1
- Telomeric repeat-binding factor 1
- SUN domain-containing protein 2
Sequence:
MSLKPFTYPFPETRFLHAGPNVYKFKIRYGNSIRGEEIEDKEVIVQELEDSIRAVLANMDSLQPFVTEHFIVFPYKSKWERVSHLKFKHGESILTPYPFVFTLYIEMKWFAEDLPSGKPADDIPLELVLAETEAEEATMRKWKRKLMEEPSSPSRQGPHRAKMETSSEASSNKKPLKESKRSTDEEAQQEYQDTPASNAIAVKEQDAALGHGLQGLVVPPLQHSSPPPPKEPGARGFLGFLSALFPFRYFFKKSGQ
Protein: Bifunctional alpha-galactosidase/sucrose kinase AgaSK [Includes: Alpha-galactosidase (EC 3.2.1.22) (Melibiase); Sucrose kinase (EC 2.7.-.-)] (G4T4R7)
Organism: Mediterraneibacter gnavus (Ruminococcus gnavus)
Function: Bifunctional enzyme with alpha-galactosidase and sucrose kinase activities. Produces sucrose-6-phosphate directly from raffinose. Binds ATP. Phosphorylates sucrose specifically on the C6 position of glucose in the presence of ATP. Hydrolyzes melibiose, raffinose, stachyose and synthetic substrate p-nitrophenyl-alpha-D-galactopyranoside with high activity. Low activity against locust bean gum, guar gum and synthetic substrates xylose alpha-D-4-nitrophenol, glucose alpha-D-4-nitrophenol and o-nitrophenyl-alpha-D-galactopyranoside.
Interaction partners:
Sequence:
MAIIYNPNKKIFTLHTAHTTYQMQVDPLGYLLHLYYGEKTNSSMDYVLTYADRGFSGNPYAAGMDRTYSLDALPQEYPSLGTGDYRNIALNIKNEKGVESADLLFKSYEIRNGKYRLQGLPAVWADEKEAQTLEIVLADENAQVEVHLLYGVLEENDVITRSVRIKNTGTGQITIEKAAAACLDFVQGEFDVLRFYGKHAMERNLERTPLGHGTIAFGSRRGTSSHQYNPAVILAEKGTTETAGSCYGMLFVYSGNFSCEAEKDQFNQTRLLLGLNEELFSYPLASGETFTVPEVILSYSAEGLSALSQQYHNCIRNHVCRSKYVHMQRPVLINSWEAAYFDFTGDTIVDLAKEAASLGIDMVVMDDGWFGKRNDDNSSLGDWQVNETKLGGSLAELITRVHEQGMKFGIWIEPEMINEDSDLYRAHPDWAIRIQGKKPVRSRNQLLLDFSRKEVRDCVFDQICVVLDQGKIDYVKWDMNRSMADVYAGNLSYDYVLGVYDFMERLCSRYPDLLLEGCSGGGGRFDAGMLYYSPQIWCSDNTDAINRTRIQYGTSFFYPVSAMGAHVSAVPNHQTGRVTSFHTRGVTAMAGTFGYELNPALLSDEEKQQIREQIKTYKKYETLINEGTYWRLSDPFTDEIAAWMSVSEEQDHALVSVVRLMAEANQATVYVRLRGLKPDAVYLEEQSGRQYSGAALMHAGIPLPPFTEEYEAYQFAFTELKEAGRLYEKVQKWCDGNAENRVVISIYGGSGSGKTTLATALQQYFLNDGTECYLLSGDDYPHRIPKRNDEERMRVYKEAGEDGLRGYLGTKKEIDFDRINEVLAAFHEGKDSITLRHMGREDGEISLEETDFSGISVLLLEWTHGGSDDLHGVDLPVFLESSPGETRERRIRRNRDENAASPFICRVVELEQEKLEVQRKNAGLIVGKDGSVYEQ
Protein: DNA helicase (EC 3.6.4.12) (B1AR17)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Chromodomain-helicase-DNA-binding protein 4
- Histone-binding protein RBBP7
- Histone deacetylase 1
- Histone-binding protein RBBP4
- Histone deacetylase 2
- Transcriptional repressor p66 alpha
- Transcriptional repressor p66-beta
- Metastasis-associated protein MTA2
- Metastasis-associated protein MTA1
- Sal-like protein 1
Sequence:
MASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEVEAADEDDEEEDEEGVLGRGPGHDRSRDRHSPPSCHLFPPPPPPLPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKLDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKRGEGDGGHKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPPALPPPPAPEIQPPPIRRAKTKEGKGPGHKRRNKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKAGSCAFQSEEGHEPEAEESDLDSGSVHSASGWPDGPVRAKKLKRGRPGRKKKKVLGCPAVTGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKEGVQWEAKEEEEEYEEEGEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSMDKKGNYHYLVKWKDLPYDQSTWEEDEMNIPEYDDHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLLLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSAESKRSSRASSPTKTSPTTPEASTTNSPCTSKPATPAPSEKGDGVRTPLDKDDTENQEEKPEKNSKVGEKMEAEVDSPSPAPSLGERLEHRKILLEDEAPGVPGETEPEPGYRGDREKSASEPTPGERGEEKPLDVQEHRERTEGETGDLGKREDVKADRELRLGPPRDEPRPNGRREEKVEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAFPPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITATTNGPPVLVKKEKEMVGALVSDGLGLDRKEPRAGEVICIDD
Protein: Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90) (Q8WXW3)
Organism: Homo sapiens (Human)
Function: Plays a role in ciliogenesis.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843}. Cytoplasm {ECO:0000269|PubMed:25218441}. Secreted {ECO:0000269|PubMed:25218441}. Note=In progesterone-treated astrocytoma cells a 57 kDa protein and isoform 1 (90 kDa) have been described, both being located in the intracellular medium and secreted. Respective predominant forms are isoform 1 in the intracellular and the 57 kDa protein in the extracellular medium (PubMed:25218441). {ECO:0000269|PubMed:25218441}.; SUBCELLULAR LOCATION: [Isoform 1]: Nucleus {ECO:0000269|PubMed:14634107, ECO:0000269|PubMed:25218441}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15305375}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:21224392, ECO:0000269|PubMed:26297806}. Secreted {ECO:0000269|PubMed:25218441}. Note=Localizes to centriolar satellites throughout the cell cycle. {ECO:0000269|PubMed:26297806}.; SUBCELLULAR LOCATION: [Isoform 4]: Secreted {ECO:0000269|PubMed:14634107, ECO:0000269|PubMed:3863495}. Note=Secreted by progesterone-treated lymphocytes (PubMed:14634107). {ECO:0000269|PubMed:14634107}.
Interaction partners:
- Coiled-coil domain-containing protein 14
- Pericentrin
- Centrosomal protein of 135 kDa
- Centrosomal protein of 63 kDa
- Krueppel-like factor 5
- Centriole and centriolar satellite protein OFD1
- Galectin-1
Sequence:
MSRKISKESKKVNISSSLESEDISLETTVPTDDISSSEEREGKVRITRQLIERKELLHNIQLLKIELSQKTMMIDNLKVDYLTKIEELEEKLNDALHQKQLLTLRLDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQENYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHDELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAERVLFSYGYGANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQTQQPYRYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQILVKMHSKHSENSLLLTKTEPKHVTENQKSKTLNVPKEHEDNIFTPKPTLFTKKEAPEWSKKQKMKT
Protein: Cytoskeleton associated protein 5 (H0YEK7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
ISSNANMLRKGPAEDMSSKLKIMYRTYRIQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRCEMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTINFIISQVASGDINTSIQALTQIDEVLRQEDKAEAMSGHIDQFLIATFMQLRLIYNTHMADEKLEKDEIIKLYSCIIGNMISLFQ
Protein: IDS-type sesquiterpene synthase (NvIDS1) (NvTPS) (EC 2.5.1.-) (A0A386JV86)
Organism: Nezara viridula (Southern green stink bug) (Cimex viridulus)
Function: Sesquiterpene alcohol synthase that catalyzes the formation of the pheromone precursor (Z)-alpha-bisabolene from (2Z,6E)-farnesyl diphosphate.
Interaction partners:
Sequence:
MAARAPVHLRGFIARVALNKKNLHARHKLDTDIDKYYYTLHNVIIPDFMDMVKEIPGYPERIKKCVAHTTPSYFEGWAFSTELIYKTVADKQHQTERNLEKCRIIRALMDMSYAMAGILDDYVDKGEFRRGKKVWASVCEGGQEAAIYDSIAVTYLMSLMVKRHFGTDPGYSKLIELFNMVPGTAAIGNTLDILDRHDTNYYDDTMWKHSVQNKAANTVFPAATAGLIHAGVLCDDLLDRTSEVFGYTGHLFQVWDDFMEHYAVKEQSGKGAPDTKYNAKTWATLTAMAHFNEAQAKEFKACYGSTDPAKRSRVRELYDEVNLRGLYIDYLRNTYMVVEEKISKIPDPRIQSACRSYMDWLLVEPPQDEEEAESVLNN
Protein: Probable transcription factor KAN3 (Protein KANADI 3) (Q941I2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that regulates lateral organ polarity. Plays a role in lateral root formation and development.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Axial regulator YABBY 3
- Axial regulator YABBY 1
- Axial regulator YABBY 5
- Putative axial regulator YABBY 2
- Auxin response factor 4
- Homeobox-leucine zipper protein ATHB-14
- Protein ASYMMETRIC LEAVES 2
- Transcription factor AS1
- WUSCHEL-related homeobox 1
- Auxin response factor 3
Sequence:
MELFPSQPDLYLKISRRREEEQEKESQELQEQEVERRLGFQSKASDLDNKSSNNLIHTLQFTSNNEATKINSNQEHKESLDQDLRSIFMMRPIRGIPLYQNQVLDHYYYSSTSPNPFFFSEVNGQHASRRLITNPNCSFNLHNRHRRQAQPQPPRFTAKRGVRAPRMRWTTTLHAHFVHAVQLLGGHERATPKSVLELMDVQDLTLAHVKSHLQMYRTIKSTEKPTTSSGQSDCENGSQVNSEREARNLTGLWNNSSSEARFQLKAKASSGVDISSNENEWKNRRCPSNERLSSDSSSLTGTRPETETPNLDFTLATPNLSP
Protein: Occludin (Q28269)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Interacts with ZO-1.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q16625}; Multi-pass membrane protein {ECO:0000255}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q16625}.
Interaction partners:
- Tight junction protein 1
- Claudin
- Claudin
- Tight junction protein 2
- Claudin
- Tight junction protein ZO-3
- Claudin
- Tyrosine-protein kinase.
- Par-3 family cell polarity regulator.
- Claudin
Sequence:
MSSRPFESPPPYRPDEFKPNHYAPSNDVYGGDMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLVIVMCIAIFGCVASTLAWDRGYGTGLMGGSIGYPYGSGFGSYGTGYGYGFGYGYGYGGYTDPRAAKGFLLAMVAFCFIAALVIFVTSVIRSDISRTRRYYLTVIILSAFLGVMMFIATIVYIMGVNPTAQASGSLYSSQIYAMCNQFYASTATGLYMDQYLYHYCVVDPQEAIAIVLGFMVIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDMPPPPSDYVERVDSPMAYSSNGKVNDKRLYPESSYKSTPVPEVVQELPATSPADDFRQPRYSSSGHLEPPSKRAPSKGRTGRPKRLEQDHYETDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQAELDEINKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSPDYKNKRNYCKQLKSKLSHIKKMVGDYDRQKT
Protein: Small ribosomal subunit protein cS23y (30S ribosomal protein 3-2, chloroplastic) (Plastid-specific 30S ribosomal protein 3-2) (PSRP-3 2) (Q9LFV0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably a ribosomal protein or a ribosome-associated protein.
Subcellular location: Plastid, chloroplast {ECO:0000250|UniProtKB:P82412}.
Interaction partners:
- Large ribosomal subunit protein bL28c
- Large ribosomal subunit protein uL3c
- Small ribosomal subunit protein bS18c
- Large ribosomal subunit protein uL4c
- Large ribosomal subunit protein uL6c
- Large ribosomal subunit protein uL15c
- Ribosomal protein S21 family protein
- At5g63300
- Small ribosomal subunit protein bTHXc
- Large ribosomal subunit protein cL38
Sequence:
MAVQANQSASFGFRTASPSQKLSSKPIAHISLSTKLKPSSRPSLSCSTWNQGQIPARHSCINPGIFAYPPSNLTFSHELPESESPPLGKKKMRVLVKPLEKPKVVLKFVWMQKDIGVALDHMIPGFGTIPLSPYYFWPRKDAWEELKTLLESKPWISELHRVFLLNQATDIINLWQSSGGDLS
Protein: EPB41L3 protein (Q96HL7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
RWQLGGAATAAAGGARVWRPLPASRSSFPPPSPRLDLGEFEGKSPCGGTCEQPYLSLPLRYFFSPRKVVPAGCEQAPGGAPKEGFGDSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGS