wanglab/gogpt-training-data huggingface dataset:
Protein: B3 domain-containing transcription factor ABI3 (Protein ABSCISIC ACID-INSENSITIVE 3) (Q01593)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Participates in abscisic acid-regulated gene expression during seed development. Regulates the transcription of SGR1 and SGR2 that are involved in leaf and embryo degreening.
Subcellular location: Nucleus. Cytoplasm. Note=Predominantly found in the nucleus.
Interaction partners:
- Protein ABSCISIC ACID-INSENSITIVE 5
- E3 ubiquitin-protein ligase AIP2
- Basic leucine zipper 25
- Ethylene-responsive transcription factor ABI4
- Nuclear transcription factor Y subunit B-9
- Basic leucine zipper 8
- Two-component response regulator-like APRR1
- Protein phosphatase 2C 56
- Protein DELAY OF GERMINATION 1
- Ethylene-responsive transcription factor WRI1
Sequence:
MKSLHVAANAGDLAEDCGILGGDADDTVLMDGIDEVGREIWLDDHGGDNNHVHGHQDDDLIVHHDPSIFYGDLPTLPDFPCMSSSSSSSTSPAPVNAIVSSASSSSAASSSTSSAASWAILRSDGEDPTPNQNQYASGNCDDSSGALQSTASMEIPLDSSQGFGCGEGGGDCIDMMETFGYMDLLDSNEFFDTSAIFSQDDDTQNPNLMDQTLERQEDQVVVPMMENNSGGDMQMMNSSLEQDDDLAAVFLEWLKNNKETVSAEDLRKVKIKKATIESAARRLGGGKEAMKQLLKLILEWVQTNHLQRRRTTTTTTNLSYQQSFQQDPFQNPNPNNNNLIPPSDQTCFSPSTWVPPPPQQQAFVSDPGFGYMPAPNYPPQPEFLPLLESPPSWPPPPQSGPMPHQQFPMPPTSQYNQFGDPTGFNGYNMNPYQYPYVPAGQMRDQRLLRLCSSATKEARKKRMARQRRFLSHHHRHNNNNNNNNNNQQNQTQIGETCAAVAPQLNPVATTATGGTWMYWPNVPAVPPQLPPVMETQLPTMDRAGSASAMPRQQVVPDRRQGWKPEKNLRFLLQKVLKQSDVGNLGRIVLPKKEAETHLPELEARDGISLAMEDIGTSRVWNMRYRFWPNNKSRMYLLENTGDFVKTNGLQEGDFIVIYSDVKCGKYLIRGVKVRQPSGQKPEAPPSSAATKRQNKSQRNINNNSPSANVVVASPTSQTVK
Protein: Nuclear factor of activated T-cells 2 (A0A8I5ZLE7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDAPEPQSDPDGGDGPGHEPGGSSQDELDFSILFDYDYLNPIEEEPIAHKAISSPSGLAYPDDVLDYGLKPCNPLASLSGEPPGRFGESDSIGFQNFLSPAKPAGASGPSPRIEITPSHELMQAGGALRGRDAGLSPEQPALALAGMAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNAGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVAPLPAASPQRSRSPSPQPSPHVAPQDDGIPAGYPPTAGSAVLMDALNSLATDSPCGIPSKIWKTSPDPTPVSTAPSKAGLARHIYPAVEFLGPCEQEERRNSAPESILLVPPTWPKQLVPAIPICSIPVTASLPPLEWPLSNQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPEPSGRIVSLQAASNPIECSQRSAHELPMVERQDMDSCLVYGGQQMILTGQNFTAESKVVFMEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRVPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPSDEYEPSLICSPAHGGLGSQPYYPQHPMLAESPSCLVATMAPCQQFRSGLSSPDARYQQQSPAAALYQRSKSLSPGLLGYQQPSLLAAPLGLADAHRSVLVHAGSQGQGQGQGSTLPHTSSASQQASPVIHYSPTNQQLRGGGHQEFQHIMYCENFGPSSVRPGLPPVNQGQRLSPGSYPTVIQQQTAPSQRAAKNGPPVSDQKEALPSGVTVKQEQNLDQTYLDDELIDTHLSWIQNIL
Protein: Agmatine N-acetyltransferase (EC 2.3.1.-, EC 2.3.1.87) (Q9W469)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- aralkylamine N-acetyltransferase
- Palmitoyltransferase app
Sequence:
MAKPIADDIVVRQVDVGETEQLMTFLLAHYYPEEPLTAGTHPPEPEAADKEFLLSNVPFGTCFVALHEGRIVAAVVAGPKDSHEPEHMAEEARKYAGGKWGSILHLLSAVETATDVCRRFSVPSCLHVHALGVDPQLRGRNLGGRLMETVAQRGRDLGHQLVSVDCTSVYSARLVQRLGYQLINTLRYVDHLDASGQQVIRPPPPHESVQTFVLHL
Protein: Histone H2A.J (H2a/j) (Q9BTM1)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
Interaction partners:
- Histone H2B type 2-E
- Histone H2B type 1-D
- Histone H2B type 1-O
- Histone H2B type 1-H
- Histone H2B type 1-C/E/F/G/I
- Histone H2B type 1-B
- Histone H2B type 1-M
- Histone H2B type 1-N
- Histone H4
- Histone H2B type 2-F
Sequence:
MSGRGKQGGKVRAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESQKTKSK
Protein: Neuronal-specific septin-3 (G-septin) (P40) (Q9WU34)
Organism: Rattus norvegicus (Rat)
Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15485489}. Cytoplasm, cytoskeleton {ECO:0000250}. Synapse {ECO:0000269|PubMed:15485489}. Note=In cultured hippocampal neurons, predominantly localized to presynaptic terminals.
Interaction partners:
- Septin-5
- Septin-7
- Septin-8
- Septin
- Septin-11
- Septin
- Septin-2
- Septin-9
- Uncharacterized protein
- Septin-12
Sequence:
MSKGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSNLLGCIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNVIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVPATPCPTAE
Protein: Calcium-binding EF-hand family protein (Expressed protein) (O64866)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- PHD finger family protein
- Calcium-binding EF-hand family protein
Sequence:
MGVVLIDGSTVRSFVDDEEQFKKSVDERFAALDLNKDGVLSRSELRKAFESMRLLESHFGVDVVTPQDELTNLYDSIFEKFDTDQSGSVDLEEFRSEMKKIVLAIADGLGSCPITMVLDDDDDNFLKKAADLEASKLEKASS
Protein: Heat shock protein hsp-1 (Heat shock 70 kDa protein A) (P09446)
Organism: Caenorhabditis elegans
Interaction partners:
- Heat shock protein 90
- DnaJ homolog subfamily B member 13
- J domain-containing protein
- DNaJ domain
- DNaJ domain
- Stress-induced-phosphoprotein 1
- Heat shock protein 110
- J domain-containing protein
- BAG family molecular chaperone regulator 1
- BAG domain-containing protein
Sequence:
MSKHNAVGIDLGTTYSCVGVFMHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHNTVFDAKRLIGRKFDDPAVQSDMKHWPFKVISAEGAKPKVQVEYKGENKIFTPEEISSMVLLKMKETAEAFLGTTVKDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGHGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFCAEFKRKHKKDLASNPRALRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTNITRARFEELCADLFRSTMDPVEKSLRDAKMDKSQVHDIVLVGGSTRIPKVQKLLSDLFSGKELNKSINPDEAVAYGAAVQAAILSGDKSEAVQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKTAQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSATDKSTGKQNKITITNDKGRLSKDDIERMVNEAEKYKADDEAQKDRIGAKNGLESYAFNLKQTIEDEKLKDKISPEDKKKIEDKCDEILKWLDSNQTAEKEEFEHQQKDLEGLANPIISKLYQSAGGAPPGAAPGGAAGGAGGPTIEEVD
Protein: Protein nubbin (POU domain protein 1) (PDM-1) (Protein twain) (dOCT1) (dPOU-19) (P31368)
Organism: Drosophila melanogaster (Fruit fly)
Function: DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:1881906}.
Interaction partners:
- POU domain protein 2, isoform B
- Protein escargot
- Transcription factor btd
- Protein wingless
- SOX domain-containing protein dichaete
Sequence:
MVMSELRWHTASPEDNKNSLKRDLLKSTPTSAREAAVHIMQNRYISRLSRSPSPLQSNASDCDDNNSSVGTSSDRCRSPLSPALSLSHQQAKRQLMSLQPHPAHHHHNPHHLNHLNHHQYKQEEDYDDANGGALNLTSDNSRHSTQSPSNSVKSATASPVPVISVPSPVPPMISPVLAPSGCGSTTPNSMAAAAAAAAAVASTMGSGISPLLALPGMSSPQAQLAAAGLGMNNPLLTGSLSPQDFAQFHQLLQQRQVALTQQFNSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQASQQLQALQKQQQRQVDEPLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPLQITPPSSAASLKLSGMLTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEPSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQATGGVFDPAALQATVSTPEIIGRRRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPSLDSPTGADDDESSYMMH
Protein: Elongation factor 1-gamma (EF1gamma) (eEF-1B gamma) (Q9NJH0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probably plays a role in anchoring the complex to other cellular components.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19841092}. Nucleus {ECO:0000269|PubMed:19841092}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19841092, ECO:0000269|PubMed:24163433}. Note=Partially colocalizes with and binds to the microtubule cytoskeleton. {ECO:0000269|PubMed:19841092, ECO:0000269|PubMed:24163433}.
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Small ribosomal subunit protein RACK1
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein eS4
- Probable elongation factor 1-delta
- Probable elongation factor 1-beta
- Large ribosomal subunit protein uL18
- Elongation factor 1-alpha 1
- Elongation factor 1-alpha 2
- Large ribosomal subunit protein uL22
Sequence:
MVKGTLYTYPENFRAYKALIAAQYSGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEGQYLSESNAIAYLLANEQLRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNSTAKQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQQQAQQQKQEKKPKEKKEAPKKAAEPAEELDAADEALAAEPKSKDPFDALPKGTFNFDDFKRVYSNEDEAKSIPYFFDKFDAENYSIWFGEYKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASVCLFGEDGNSTISGIWVWRGQDLAFTLSPDWQIDYEVYDWKKLDAKSEETKKLVTQYFSWSGTDKDGRKFNQGKIFK
Protein: Elks delta-like protein (Q38AE0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDAKQRESIEELKEQLRGLEEALLIQEKVMQQRNQVILSLSSSIADAENSIGESKEGLKKAEESLEEAIRSNTIAHTERLVLQEEATKYSERDEYLNELSEADAGLNAAEAQVKDLVIQINDLSREPQNKNALQRVTLVRLISMLNDLHASLKHSVQCVPHEEDNRAREVLKAIRELSRERERTFGHCLRKKREIMGVMELKKQRTDEILLESKKNVALLRDIHEKTTLDAVEKIQKERNLLQEELENIKRANQLLQDTLGSTECLCDTKGSDSASTPASISMNVASCQSTDVQKEREHLREYLRHLEEKVTQLRSTTDELRESVGSQMEKNTLKLKDLRHQVRSKQNETHRLENENRKLKSLCDSLASTLGPK
Protein: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 (A2RUY6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEQQREEEPSQLDPAGPAEDDTSENGHDEASDTAMDSEAQSSSPPSAKGKDLLGGYEEKVQTDRTNRFEYLLKQTEVFAHFIQPAAQKTPTSPLKMKPGRPRIKKDEKQNLLSAGDNRHRRTEQEEDEELLSENSKATSVCTRFDDSPSYVKTGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLYNWMNEFKRWVPSLKAVCLIGDREERTAFIRDTLLPGEWDVCVTSYEMLIIERAVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSSEDFDAWFDTNNCLGDTKLVERLHTVLRPFLLRRIKADVEKSLLPKKEIKIYVGLSKMQREWYTKILMKDIDILNSAGKMDKMRLLNVLMQLRKCCNHPYLFDGAEPGPPYTTDLHLVVNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYGYCRLDGQTPHEERQISINAFNEPNSSKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQVDLQAMDRAHRIGQKKQVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDPSMNKLGKDEMLSIIRHGATHVFASKESEITDEDIDGILERGERKTMEMKEKMANLGEGSLRNFTMDTENSVYNFEGEDYREKKKVVTNWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDLPNSAEMQKEEQAKIDEAEPLNEEELEEKENLLSQGFTIWTKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDSKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKESVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEREKAEKKKRGPRTSSAQKRKQDGTPDGRGRKKKLKL
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (A0A8I6A0C2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTAAICATGLRNLGNTCFMNAILQSLRSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSANNKCCINGASTVVTTIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEGRWFHFNDSTVTVTDEETVGKAKAYILFYVERQARAGADKL
Protein: Ellipsoid body open, isoform A (FI17502p1) (Q9W5G1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MHAASLTTVEGLLQEFYQPSTSNARKREIETNLLAFKSQPEAWQLCLRVATSSDTTENQFLWFFSTSTLEHTITRRWTQLTSTDKTLLRETLWNSYAQLVATPNVAKRHRDTLAQLIALLGKREFPEQDPNYMQHCMELTKTRFQLGINLLKITSEEVVSNRGDLTTEWKQYFYSCISMCVPDVLDLVTKYLLIAVCHINGKDIQTTIPNTLMDFSLTSALPNDNQLSSSILDLLGCVQHLVSWIRTELISEYFLMSILDLSQWRPAHEPISLAALSVLNELLYLQKPLPFPGPLMGGVTSLLEQHNNNRRQSEMYSDKFRELLRLYTTKYAAKLMQEPDLLETFLNLLYSCTTELHGALDFTEKLEIWTPIIKGIAQHPAKITRYNNVLTQLVDEIMRRTQFEANKPELEVLDNELMEDDTSATEWQQFLDQCFESLALLANTRGAHIVFAQVYNHWSRPQMYLLSLEHALDHGSARSYEAARKLKGANVGEILRDFATVCQAVVRLAPLMDSSTAAPGVADEMECQLQMLSDSLLQTLQLLASNRLYSGGSEMDKATFQTDLDNLYAQVLLAMRSIFPLTKAMSGEELLHRLFAILGSIFACNGSLTAASPIVQQAASELLLFISTVIRPKCLLDIPQIQSLLQAGSRLGAQLPRQVCINVHISLVSYMVLPWKSVPEQQQEYPRRLWMLREYVQGLAQNFLDLDLGQANESKVAATTLSLLGTFTALIEYFKATGGNAKDMLASTFKPILTKALMIFNNFGQSSIAMAITVAEFSLSMLRTLPTHLGAQFIKEMITLFISVSSREQLTLSRLAVMEKILQMFKLIVEQPGSASLGLLPSILDFSTQQILPLLQQQNAATDNSEITSLLYALFDSVLTCKWQFFYKNQLSNGHSGGGSGNFNCSDNLHPAHFMAILNAYGQMLVSGTDPSNVRSVLFSMQNVNERSRLYQRALFKEQLLASFQRALLNLLLSGEGSLHFDMIAQALYAMGQVDRRQLLESFVHASLPVAQTSLEEICQTNDIPTFTQKLTQLMQDAHCVHLNETA
Protein: STI1 domain-containing protein (A7LPI4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSLADHIDAIKKEMTSLSSQFNSNKSELERSKQDLSSMQLQMQQQMNDSVQQDLQKAHDTSKKLDNLARTFLALITDPSQQSQLLAEFESISKNGTPQMPVMTPPMMNAVAAMQPHMMMRNPMLNAMGGASPRVSGKGGAPQNGGMNGMSMMQHMQMQAFQAQMMQAQMFQQMPMMMPGMVPGMPPGMAGLPGMMPPNNMAAAMQHFNAQMAAAASVAVSTPSRNPSTSGAASRTRTPLTTSATNSPRPTTEPTIKEEEPQTMEHDVAAAVAATTATATIKQEENSTVAVA
Protein: Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase) (P07902)
Organism: Homo sapiens (Human)
Function: Plays an important role in galactose metabolism.
Interaction partners:
- UDP-glucose 4-epimerase
- Galactokinase
- UTP--glucose-1-phosphate uridylyltransferase
- N-acetylgalactosamine kinase
- Galactose mutarotase
- Interleukin-11 receptor subunit alpha
- Beta-1,4-galactosyltransferase 1
- Alpha-lactalbumin
- Beta-1,4-galactosyltransferase 2
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Sequence:
MSRSGTDPQQRQQASEADAAAATFRANDHQHIRYNPLQDEWVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGAIRANGEVNPQYDSTFLFDNDFPALQPDAPSPGPSDHPLFQAKSARGVCKVMCFHPWSDVTLPLMSVPEIRAVVDAWASVTEELGAQYPWVQIFENKGAMMGCSNPHPHCQVWASSFLPDIAQREERSQQAYKSQHGEPLLMEYSRQELLRKERLVLTSEHWLVLVPFWATWPYQTLLLPRRHVRRLPELTPAERDDLASIMKKLLTKYDNLFETSFPYSMGWHGAPTGSEAGANWNHWQLHAHYYPPLLRSATVRKFMVGYEMLAQAQRDLTPEQAAERLRALPEVHYHLGQKDRETATIA
Protein: Tyramine beta-hydroxylase (EC 1.14.17.-) (Tyramine beta-monooxygenase) (TbetaM) (Q86B61)
Organism: Drosophila melanogaster (Fruit fly)
Function: Converts tyramine into octopamine, a neurotransmitter involved in ovulation and locomotion. Functions in an amine-mediated Bacc-dependent signaling pathway that negatively regulates acute ethanol sensitivity.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- MIP05841p)
- Aromatic-L-amino-acid decarboxylase
- monoamine oxidase
- Octopamine receptor Oamb
- Octopamine receptor beta-2R
- Tryptophan 5-hydroxylase 2
- GH10249p
- FI02861p)
Sequence:
MLKIPLQLSSQDGIWPARFARRLHHHHQLAYHHHKQEQQQQQQQQQQQQAKQKQKQNGVQQGRSPTFMPVMLLLLMATLLTRPLSAFSNRLSDTKLHEIYLDDKEIKLSWMVDWYKQEVLFHLQNAFNEQHRWFYLGFSKRGGLADADICFFENQNGFFNAVTDTYTSPDGQWVRRDYQQDCEVFKMDEFTLAFRRKFDTCDPLDLRLHEGTMYVVWARGETELALEDHQFALPNVTAPHEAGVKMLQLLRADKILIPETELDHMEITLQEAPIPSQETTYWCHVQRLEGNLRRRHHIVQFEPLIRTPGIVHHMEVFHCEAGEHEEIPLYNGDCEQLPPRAKICSKVMVLWAMGAGTFTYPPEAGLPIGGPGFNPYVRLEVHFNNPEKQSGLVDNSGFRIKMSKTLRQYDAAVMELGLEYTDKMAIPPGQTAFPLSGYCVADCTRAALPATGIIIFGSQLHTHLRGVRVLTRHFRGEQELREVNRDDYYSNHFQEMRTLHYKPRVLPGDALVTTCYYNTKDDKTAALGGFSISDEMCVNYIHYYPATKLEVCKSSVSEETLENYFIYMKRTEHQHGVHLNGARSSNYRSIEWTQPRIDQLYTMYMQEPLSMQCNRSDGTRFEGRSSWEGVAATPVQIRIPIHRKLCPNYNPLWLKPLEKGDCDLLGECIY
Protein: Sorting nexin-14 (Q9Y5W7)
Organism: Homo sapiens (Human)
Function: Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking (By similarity). Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes. Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)).
Subcellular location: Lysosome membrane {ECO:0000269|PubMed:25848753}; Multi-pass membrane protein {ECO:0000305}. Late endosome membrane {ECO:0000269|PubMed:25848753}; Multi-pass membrane protein {ECO:0000305}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8BHY8}.
Interaction partners:
- Sorting nexin-13
Sequence:
MVPWVRTMGQKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYIHILMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKISSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKLNRGSLSLDDFRNTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNYFMEVMTVEGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEVTSVTSWM
Protein: MADS-box transcription factor 17 (NMADS3) (OsMADS17) (RMADS213) (Q7XUN2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor. Plays minor but redundant roles with MADS6 in floral development.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MGRGRVELKRIENKINRQVTFSKRRNGLLKKAYELSVLCDAEVALIIFSSRGKLYEFGSAGINKTLEKYNSCCYNAQGSNSALAGGEHQSWYQEMSRLKTKLECLQRSQRHMLGEDLGPLSIKELQQLEKQLEYSLSQARQRKTQIMMEQVDDLRRKERQLGELNKQLKNKLEAEADSSNCRSAIQDSWVHGTVVSGGRVLNAQPPPDIDCEPTLQIGYYQFVRPEAANPRSNGGGGDQNNNFVMGWPL
Protein: Histidine decarboxylase (HDC) (EC 4.1.1.22) (P19113)
Organism: Homo sapiens (Human)
Function: Catalyzes the biosynthesis of histamine from histidine.
Interaction partners:
- Histamine N-methyltransferase
- Diamine oxidase [copper-containing]
- Cytosolic non-specific dipeptidase
- Histidine ammonia-lyase
- Beta-Ala-His dipeptidase
- Carnosine synthase 1
- Mast cell carboxypeptidase A
- High affinity immunoglobulin epsilon receptor subunit beta
- Histamine H2 receptor
- Histamine H1 receptor
Sequence:
MMEPEEYRERGREMVDYICQYLSTVRERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGDIERIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDADESCLNARLVAYASDQAHSSVEKAGLISLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVFVCATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSVKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAKRHLGLVVFRLKGPNCLTENVLKEIAKAGRLFLIPATIQDKLIIRFTVTSQFTTRDDILRDWNLIRDAATLILSQHCTSQPSPRVGNLISQIRGARAWACGTSLQSVSGAGDDPVQARKIIKQPQRVGAGPMKRENGLHLETLLDPVDDCFSEEAPDATKHKLSSFLFSYLSVQTKKKTVRSLSCNSVPVSAQKPLPTEASVKNGGSSRVRIFSRFPEDMMMLKKSAFKKLIKFYSVPSFPECSSQCGLQLPCCPLQAMV
Protein: Prolactin-4A1 (Placental prolactin-like protein A) (PLP-A) (PRL-like protein A) (O35256)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Decidual PRL-related protein
- Trophoblast-specific protein alpha
Sequence:
MHLSLTPQWSSWTVLLLLVSNLLLWENTASAMRAKRLNVHDYTTFGNTWNQAIQLSQSMNHRISELSTHFKVFYAQGRGFEKRTTRCHTSSLSSPENKEQAQKIQLEVLLGLAHSLLQAWVNPLYHLWAEMCERLGSTPPILSKALEVKTLNRNLLETIEKIAFKGNFEINENGNYTAWSELELLQSPNRDTRYFAFHNLFHCLKKDSSHVEMYLKLLKCRLIQSNC
Protein: tRNA N(3)-cytidine methyltransferase METTL8, mitochondrial (EC 2.1.1.-) (Methyltransferase-like protein 8) (Tension-induced/inhibited protein) (mRNA N(3)-methylcytidine methyltransferase METTL8) (EC 2.1.1.-) (A2AUU0)
Organism: Mus musculus (Mouse)
Function: Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of mitochondrial tRNA(Ser)(UCN) and tRNA(Thr) (By similarity). N(3)-methylcytidine methylation modification regulates mitochondrial translation efficiency and is required for activity of the respiratory chain (By similarity). N(3)-methylcytidine methylation of mitochondrial tRNA(Ser)(UCN) requires the formation of N(6)-dimethylallyladenosine(37) (i6A37) by TRIT1 as prerequisite (By similarity). May also mediate N(3)-methylcytidine modification of mRNAs. The existence of N(3)-methylcytidine modification on mRNAs is however unclear, and additional evidences are required to confirm the role of the N(3)-methylcytidine-specific mRNA methyltransferase activity of METTL8 in vivo (By similarity).
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9H825}. Cytoplasm {ECO:0000305|PubMed:15992539}. Nucleus {ECO:0000305|PubMed:15992539}. Note=Mitochondrial protein (By similarity). The cytoplasmic or nuclear localization observed by some groups is either the result of an incorrect localization caused by N-terminal tagging that interferes with mitochondrial targeting, or splice isoforms that lack the N-terminal mitochondrial transit sequence (By similarity). {ECO:0000250|UniProtKB:Q9H825}.; SUBCELLULAR LOCATION: [Isoform 5]: Nucleus {ECO:0000269|PubMed:15992539}. Note=Isoform 5 localizes to the nucleus upon cell stretch in embryonic lung progenitor cells. {ECO:0000269|PubMed:15992539}.
Interaction partners:
- Probable methyltransferase-like protein 25
- EEF1A lysine methyltransferase 2
- TLC domain-containing protein 4
Sequence:
MNVIWRSCICRLRQGKVPHRCQSGVHPVAPLGSRILTDPAKVFEHNMWDHMQWSKEEEDAARKKVEENSATRVAPEEQVKFESDANKYWDIFYQTHKNKFFKNRNWLLREFPEILPVNQNTKEKVGESSWDQVGSSISRTQGTETHCQESFVSPEPGSRGRSAPDPDLEEYSKGPGKTEPFPGSNATFRILEVGCGAGNSVFPILNTLQNIPGSFLYCCDFASEAVELVKSHESYSEAQCSAFIHDVCDDGLAYPFPDGILDVVLLVFVLSSIHPDRALFI
Protein: Myosin-13 (Myosin XI G) (AtXIG) (F4IUG9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity).
Interaction partners:
- Ras-related protein RABC2a
Sequence:
MVFKVFSFVAFMACSTVKVGSIVWVQDPEEAWIDGEVVEVNGEDIKVQCTSGKTVVAKGSNTYPKDMEVPPSGVDDMTTLAYLHEPGVLQNLKSRYYIDEIYTYTGNILIAVNPFKQLPNLYNDHMMAQYKGAALGELSPHPFAVADAAYRQMINEGISQSILVSGESGAGKTETAKMLMKYLAKMGGRAVSDRRTVEDQVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDQRGRISGAAIRTYLLERSRVCQVSDPERNYHCFYMLCAAPPEDKRKLKLNDPTEFRYLNQSHCIKLDGVDDSKEYTKTREAMGIVGINLEEQEAIFRVVAAILHLGNIEFAIGEEPDSSVPTDESKKYLKIAAELFMCDEQALEDSLCKRIMVTPEETISRCLDPNSAALSRDALAKFVYSRLFDWIVNKINNSIGQDPDSKDMIGVLDIYGFESFKTNSFEQFCINLTNEKLQQHFTQHVLKMEQEEYTKEEIEWSQITFPDNRYVLELIEKKRGGIIALLDEACMFPRSTHKTFSQKLYETLKDNKYFSKPKLSRTDFTICHYAGDVTYQTEQFLEKNKDYVVAEHQALLGASRCTFIAGLFPPLVEDANKQSKFSSIASQFKQQLASLIEGLNTTEPHYIRCVKPNNLLKPSIFENQNSLQQLRCGGVMETIRVCRAGYPTRKHFDEFLDRFGILDSATLDKSSDEKAACKKLLETVGLNGFQIGKTKVFLKAGQMAELDDRRTEVLGRAACIIQWKFRSYLTRQSFIMLRNAAINIQAVYRGQVARYRFENLRREAAALKIQRALRIHLDRKRSYIEAVVTVQSGLRGMAARVVLRRKTKATTVIQSHCRRLRAELHYKKLKKAAITTQSAWRARLARKELRKLKTDARDTVVLQAAKSMLAEKVEELTWRLDLEKRMRVDMEVSKAQENAKLQLALEEIQLQFEETKVSLLKEVEAAKKTAAIVPVVKEVPVVDTVLMEKLTSENEKLKSLVTSLELKIDETEKKFEETKKISEERLKKALDAENKIDNLKTAMHNLEEKLKEVKLENNFLKESVLTTPVKTASGRFLSTPLKNLQNGLFTSEESQLSGAEFTTPPRIQESGSDTKSRGSHIDPQHEDVDALINSVTKNVGFSQGKPVAAFTIYKCLLHWKSFEAERTNVFDRLVQMIGSAIKDEDNDANLAYWLSNTSTLLFMLQQSLKSGGTGATPLRQSPSLVRWMTKGFRSPAAEAIRPVDAKDPALHFKQQLEAYVEKILGIIWDNLKKELNTVLALCIQAPKTFKGNALISITTANYWQDIIEGLDALLSTLKESFVPPVLIQKIFSQAFSLINVQVCNSLVTRPDNCSFINGEYLKSGLEKLEKWCCETKEEYAGSSWDELKHTRQAVGFLLIHKKYNISYDEIANDLCPNLQIQQHFKLCTLYKDEIYNTKSVSQDVIASMTGVMTDSSDFLLKEDSSNIISLSIDDLCSSMQDKDFAQVKPAEELLENPSFIFLH