wanglab/gogpt-training-data huggingface dataset:
Protein: Myosin IC heavy chain (P42522)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Involved in the process of phagocytosis and appears to support streaming behavior.
Subcellular location: Cell projection, lamellipodium {ECO:0000269|PubMed:11425877, ECO:0000269|PubMed:2797149, ECO:0000269|PubMed:8325874, ECO:0000269|PubMed:8609164}. Note=Found in the leading edge of translocating cells.
Interaction partners:
- Calcium-binding EF-hand domain-containing protein
Sequence:
MAQQKPEWGNQMKNEGLDDMTLLSKVSNDQILDNLKKRFEKDIIYTNIGDVLISVNPFKFIDGMYSDEVLQEYIGKSRIELPPHVFAVAEQTYRSMINEKENQCVIISGESGAGKTEAAKKIMQYIADVSGERGSSSNQKVEHVKSIILETNPLLEAFGNAKTLRNNNSSRFGKYFEIQFNQKNEPEGGKITNYLLEKSRVVFQLKGERNFHIFYQFCRGATPQEQQEFGIYGPENFAYLTKGDTLDIDGVDDVEEFALTRNAMNVIGIPANEQKQIFKLLAAILWIGNIDFKEQAGDKVTIADTSVLDFVSQLLDVPSHFLKTALEFRQMETRHGNQRGTQYNVPLNKTQAIAGRDALAKAIYDRLFNWLVDRINKEMDNPQKGLMIGVLDIYGFEVFDRNGFEQFCINYVNEKLQQIFIEFTLKMEQEEYVREGIKWEPIPFFDNKIVCELIEGKNPPGIFSILDDVCRAVHSQAEGADQKLLQSIAVCKSNPHFDTRGNAFCVKHYAGDVVYEGPGMIEKNKDTLLKDHLEILQMSANNFLVGLFPDVIDTDSKKLPSTAGFKIKSQAAELVATLMKSTPHYIRTIKPNDLKKPNILEGGRVLHQVKYLGLLDNIKVRRAGFAYRATFDRFFQRYYLLSDKTCYAGNNIWKGDALSACRAILASQNVDNTQYQIGKTKIFIRYPEMLFSLEETRERYWHDMASRIKNAYRNYKAFQFECSNRIKNAFRNYKLYRQRCAQTIQGYFRAWKQASPFFDLRMQNEQLFQGRKERNRFSMISVRKYFGDYLDVRSQSYFLDAMAEGRNEDVIFSSKSQVMVHPILSANKLSPRFLIVTKQAIYLIKLKQKKNLATYLLDRRVPLAEVTSFSLSSLADNLLVIHTSTQFDVAVTTEFKTELVALINKQKGTTLAVNFGQSIQYFKKKGSNNTVTFLKDEMHKEIFLKKNQFHIASGLPASTTVAKVRKNPSQVSTPSKPIAKPVAKPMVAKPSGGSVIMKKPAPAAPPSGPPVMKKPAPTAPGGAPMMKKPAPAPGGAPMMKKPAPVPGGPAPGGSAIMKPAGGVSKPLPSPTGAPMMKKPAPTAPGGPAPAGAPTPMMKKPAGQPMMKPIAKPQPTPMKKPAAPPPQQYIALYEYDAMQPDELTFKENDVINLIKKVDADWWQGELVRTKQIGMLPSNYVQQI
Protein: Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3) (Q15738)
Organism: Homo sapiens (Human)
Function: Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Also plays a role in the regulation of the endocytic trafficking of EGFR (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21129721}; Single-pass membrane protein {ECO:0000255}. Lipid droplet {ECO:0000250|UniProtKB:Q9R1J0}. Note=Trafficking through the Golgi is necessary for ER membrane localization. {ECO:0000250|UniProtKB:Q9R1J0}.
Interaction partners:
- Methylsterol monooxygenase 1
- 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
- Lanosterol 14-alpha demethylase
- Squalene monooxygenase
- Lathosterol oxidase
- 7-dehydrocholesterol reductase
- 3-beta-hydroxysteroid-Delta
- Squalene synthase
- Lanosterol synthase
- Ubiquitin-like protein FUBI
Sequence:
MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
Protein: Protein hairless (Q02308)
Organism: Drosophila melanogaster (Fruit fly)
Function: Is a potent antagonist of neurogenic gene activity during sensory organ development. The expression of distinct cell fates by the trichogen (shaft) / tormogen (socket) sister cell pair depends on the level of H activity. A certain threshold level of H activity is required, below which both sister cells adopt the tormogen fate.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Suppressor of hairless protein
- Protein groucho
- C-terminal-binding protein
- Neurogenic locus Notch protein
- Histone deacetylase HDAC1
- Protein mothers against dpp
- Protein insensitive
- Schnurri, isoform F
- Mothers against decapentaplegic homolog
Sequence:
MALLNDVTSVAECNRQTTMTDEHKSNINSNSSHSSNNNNNGSSSNNDNNSNDDAASSSNSKNNNTSNESSHSNNNTSSIIAEAAAKFLLKNGLNGSSSTSYPPLPPPLPANLSRTTTPTTTTTPSSSSSTASNGFLPHAKTPKSSSIMAASAAVAASVVGATASKPTIDVLGGVLDYSSLGGAATGSLPTTAVVAAAAGTAKIGKGSNSGGSFDMGRTPISTHGNNSWGGYGGRLQFFKDGKFILELARSKDGDKSGWVSVTRKTFRPPSAATSATVTPTSAVTTAYPKNENSTSLSFSDDNSSIQSSPWQRDQPWKQSRPRRGISKELSLFFHRPRNSTLGRAALRTAARKRRRPHEPLTTSEDQQPIFATAIKAENGDDTLKAEAAEAVEIENVAVADTTTNEIKIEKPDTIKGEDDAERLEKEPKKAVSDDSESKEASPGQQVEPQPKDETVDVEMKMNTSEDEEPMTELPRITNAVNGDLNGDLKASIGKPKSKPKPKAKLSSIIQKLIDSVPARLEQMSKTSAVIASTTTSSDRIGGGLSHALTHKVSPPSSATAAGRLVEYHTQHVSPRKRILREFEKVSLEDNGCVNNGSGGASSGGAGGKRSRAKGTSTSSPAGKASPMNLAPPQGKPSPSPGSSSSSTSPATLSTQPTRLNSSYSIHSLLGGSSGSGSSSFSSSGKKCGDHPAAIISNVHHPQHSMYQPSSSSYPRALLTSPKSPDVSGSNGGGGKSPSHTGTKKRSPPYSAGSPVDYGHSFYRDPYAGAGRPSTSGSASQDLSPPRSSPASPATTPRTVPKKTASIRREFASPSASSSSCPSPGDRSASPPERRHMQQQPHLQRSSPLHYYMYPPPPQVNGNGSAGSPTSAPPTSNSSAAAVAAAAAAAAAYIPSPSIYNPYISTLAALRHNPLWMHHYQTGASPLLSPHPQPGGSAAAAAAAAAARLSPQSAYHAFAYNGVGAAVAAAAAAAAFGQPAPSPHTHPHLAHPHQHPHPAALTTHHSPAHLATPKLTDSSTDQMSATSSHRTASTSPSSSSASASSSAATSGASSSAMFHTSSLRNEQSSDLPLNLSKH
Protein: Fibulin-7 (FIBL-7) (Q53RD9)
Organism: Homo sapiens (Human)
Function: An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Transmembrane protein 87B
- Dentin sialophosphoprotein
Sequence:
MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKSRLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLDRSFQANHVSKVTIFVSPYDF
Protein: BCL2 interacting protein 3 like (A0A8I6AG85)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
MDFLTSFIFIFFRRLWLLFEASQNSYLNPAYGHLWHRRDFGPAVVLTYYLSRPTGSWVELPMNSSNGNGNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVDGEKEVEALKKSADWVSDWSSRPENIPPKEFLFRHPKRAASLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY
Protein: Arginine methyltransferase 1 (EC 2.1.1.319, EC 2.1.1.321) (CG6554 protein) (CG6554-PA) (LD28808p) (Q9VGW7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Forkhead box protein O
- Protein big brother
- 39 kDa FK506-binding nuclear protein
- Protein arginine N-methyltransferase 5
- Nucleolar complex protein 2
- histone acetyltransferase
- Histone H3
- Estrogen-related receptor splice variant
- Pre-rRNA-processing protein TSR1 homolog
Sequence:
MASTDIPMEAAVESATGITPNSNANSNNVAKKLPAEGSTGDNPNANADEMTSRDYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTEPLVDVVDPKQVVSTSCMVKEVDLYTVQKADLNFSSKFSLCIKRNDFVQALVTYFNIEFTKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDINFKGELSQIQESNTYRMR
Protein: T-box transcription factor TBX1 (T-box protein 1) (Q8AXX2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Probable transcriptional regulator involved in developmental processes (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence (By similarity). Is required for normal development of the pharyngeal arch arteries (By similarity). Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Prickle homolog 1b
- Prickle homolog 2b
- Prickle homolog 2a.
- Prickle homolog 1a
- Vang-like protein 2
- Vang-like protein
- Protein max
- Cadherin EGF LAG seven-pass G-type receptor 1
- Ankyrin repeat domain 6b
- Protein Wnt-5b
Sequence:
MISAISSPWLTQLSHFCDVAAFTTSSLSSLNTPGSYHLSPSPGDPYSHHESQFEPCPAAQHAYNYSGSNSAQAPAQGDSGTSNCSSSSSSSTPNKTLVKKNPKVANINVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFLPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENYKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLQIMSAFARTRNPMSSPPQQNGTEKEDSRREYDRDPSGNPLHSDPTHQLMSRVLSPALPVLGGLHAVPLTAGPRSPPHELRLDGHPQPPDTLHHHPYKYPATYEHYLGAKTRPSPYPSPSIRGHGYHPHMNPTTANMYSATSAPTNYDYGPR
Protein: Protein ZRG17 (Zinc-regulated gene 17 protein) (P53735)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Probable zinc transporter MSC2
- Vacuolar zinc transporter COT1
- Vacuolar zinc transporter ZRC1
- Zinc-regulated transporter 1
- Zinc-regulated transporter 2
- Zinc-regulated transporter 3
- Zinc-responsive transcriptional regulator ZAP1
- Zinc transporter YKE4
- Low-affinity Fe
Sequence:
METPQMNAIQEEDNLSPEVAFQTPKLNDSDASSFSLSNMNAVGNVDGIPSQNRTFFASPRPSSLFYSAKEGNNSSSSIIYNPSFTFGENASSNANINEAALMKGKGNEGRRQSLKYIPAPKLVPPPPRTRSPVRGISPDAGSSKRSSMTLDSPFNFTTSTLQPHQQTPPSSAASRTSFRKGHRYKHSSVSMNFFQEPEVKIPLNIAKSLPIPDFNDLLSNLPWPKAYIQLSIAALQIFACLITFQVGHLYSWSNFITLSHFITYDIIGSLVIIFVENLSQFQVWFTGTITFPFGLNRIDVLLSFALAVSLCFVGLDLLFHIIEEFIVLFVESGSSLTNNHDHDEINEQIPHSHIANANDSQNENITLWYSILMINLVLSTLSLYKTFYANKYSNLKTKNPIITITYTAYLFIYPLLLDLLSSISDYLATLVISSLILWHGLTIARWTSTVLLMGFSTTSLSNSALFNNNDSTDTTAHTQQVESKAAKEKPSVRPRSMSSLPIATKNTKIRKTGFLNSAGFTENPTTIKNMIKDQIERLSEFKSRYILNYDDIVISKVNFTLYVVLIKITMKGGSDDDELMLRLAIDKCIQTSIPTCETTIDIDRI
Protein: GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1) (Q9BZE4)
Organism: Homo sapiens (Human)
Function: Involved in the biogenesis of the 60S ribosomal subunit. Acts as TP53 repressor, preventing TP53 stabilization and cell cycle arrest.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:11316846, ECO:0000269|PubMed:12429849, ECO:0000269|Ref.8}.
Interaction partners:
- mRNA turnover protein 4 homolog
- Ribosome biogenesis protein NSA2 homolog
- Pescadillo homolog
- Nucleolar GTP-binding protein 2
- Ribosome production factor 2 homolog
- Probable ribosome biogenesis protein RLP24
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- Eukaryotic translation initiation factor 6
- 60S ribosomal export protein NMD3
- Ribosome biogenesis protein BRX1 homolog
Sequence:
MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTVIKRQKQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEDDQKIFTDLQSEGFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAIPTRRDDKERPPFIPEGVVARRKRMETEESRKKRERDLELEMGDDYILDLQKYWDLMNLSEKHDKIPEIWEGHNIADYIDPAIMKKLEELEKEEELRTAAGEYDSVSESEDEEMLEIRQLAKQIREKKKLKILESKEKNTQGPRMPRTAKKVQRTVLEKEMRSLGVDMDDKDDAHYAVQARRSRSITRKRKREDSAPPSSVARSGSCSRTPRDVSGLRDVKMVKKAKTMMKNAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR
Protein: Novopsin-4 (Opsin 7, group member b) (E7FEE5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MENSSETDLFQSKISKENDLLLGTIYSIFGVLSLMGNSTLLFVAYRKKSSLKPAELFIINLSISDLGMTVFLFPFAIPSAFAHKWLFTEVMCMCYAFCGVLFGLCSLSNLTVLSCVCWLKVCCPNYGNKFSSCHARLLVVGVWCYAAVFAVGPLSGWGQYGSEPYGTACCIDWHAPSSSTPAMIYIVCLFFFCYIVPCCVIILSYSLILVTVRGAQHAVQQHVSPQNKISNVQTLLVKLSVAVCFGFLMAWSPYAVVSMWAAFTEPDLVPPIAFALAAMFAKSSTLYNPMVYLVFKPSFRKSLCRDATKCKRKLCPCVCQTDTQHQGTPSLNTKDKCKLTWVSNGLNESHQSCRHCPERQTGNYLDITPQRTARVLTGTTHNEVALSQLSNEINSDFL
Protein: Parathymosin (P20962)
Organism: Homo sapiens (Human)
Function: Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.
Interaction partners:
Sequence:
MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGASA
Protein: Hyperkinetic, isoform H (M9NF11)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MPTTASCRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAHSETEIGKILQRAGWKRTAYVITTKVYWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCPMEVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMISTLALR
Protein: Mitochondrial magnesium exporter 1 (Q03829)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transporter of the mitochondrial inner membrane that exports magnesium and thus, plays a key role in mitochondrial Mg(2+) homeostasis.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:25585246}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Mitochondrial inner membrane protease subunit 2
- mRNA-binding protein PUF3
Sequence:
MNSWNLSSSIPIIHTPHDHPPTSEGTPDQPNNNRKDDKLHKKRGDSDEDLSPIWHCVVSGGIGGKIGDSAMHSLDTVKTRQQGAPNVKKYRNMISAYRTIWLEEGVRRGLYGGYMAAMLGSFPSAAIFFGTYEYTKRTMIEDWQINDTITHLSAGFLGDFISSFVYVPSEVLKTRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKFRQLAFKIEQKDGRDGELSIPNEILTGACAGGLAGIITTPMDVVKTRVQTQQPPSQSNKSYSVTHPHVTNGRPAALSNSISLSLRTVYQSEGVLGFFSGVGPRFVWTSVQSSIMLLLYQMTLRGLSNAFPTD
Protein: CUB-like domain-containing protein (O02362)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MVFTMRVPVFLLFFFGLSEAVDFNCPANNITSVRQNGNIPEGATSSVVIPKGTDCTINFDIPNGYALFLQLSVGPLQADDHILLIDNNNQQREVRPTTNDTTIPVWLAATIATIKIKGTTGNSKFMVTYRFNQLIGFTQVKKTTGDYFDLSQLTGNTYFTFNSSPNDKVRVAHGKKTSDAEDNALDQIFVYDGDNLTTAKMIGTLADIGSPKSDIKSSSTSLTLVNFYGTKSTSYVIGNDATTMIGYSKYSFIVSNSGRKTYGNMGDLSGNVGGYTFLCLDCNQFYFTELQFATFSNGWVNFQGQSPTHKKETLIQYDAQTYTSSQMPQVIPTNMFTINIHLATIKFDVNTGNDEATWQRPYDGRKGYIISPSLWNPNANPNNLNYDFRNDTQLFTYKVDFERMKFSSNDQMTLQIGSGTGNPAINNQYPRDKSSTGSVSSNGNYMKVGLTASSNTEVRVAFEFKKYNSATSIGIFITLFVTLLRVF
Protein: von Willebrand factor C domain-containing protein 2-like (B0UZC8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May play a role in bone differentiation and matrix mineralization (By similarity). May play a role in neural development.
Subcellular location: Secreted {ECO:0000250}. Synapse {ECO:0000250}.
Interaction partners:
- Odorant receptor
- Odorant receptor
- Olfactory receptor
- Kinesin family member 26Bb
- Olfactory receptor
- Odorant receptor
Sequence:
MGPFLPAICVVLLALNAAVSPASVGPEDYPAADEAERTANNDIIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYRGKTYKILEEFKPSPCEWCRCEPNNEVHCVVADCAVPECVNPVYEPEQCCPICKNGPNCFAGTTIIPAGIEVKVDDCTICRCHSGDWWKPAQCLRRECLNGQATS
Protein: Activity-dependent neuroprotective protein a (ADNP homeobox protein a) (F1QLG5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May be involved in transcriptional regulation. Positively modulates wnt-beta-catenin/ctnnb1 signaling. Required for embryonic neurogenesis. Required for progression through late erythroid differentiation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MFQLPVNNLTRLRKARKKVKRLLSDIGLDYCKEHVEDYKDVDPDDSDDSNESHLDLCTWDPTWTKSQDYRTKQFCCSDCPFASKYFSAYKNHFRNVHREDFESRILLNCSYCTYSGNKRTLETHVRLFHMPHNVMRQGVVGPHGAPVGAKDGMRVDKPMLGDRKELPVYYCKKCTYRDRLYNVVRRHIYREHFQHVATPYLGKNSEKQVNSGEAQANSHGIHCKSCHFTPRSYEALVQHVIEFHERIGHQVTAMIGHTNVIVPRLQTNPIQRGVPITSGVRPQTPQMNRFSMPKVVGLPVGNHFKQSLAGNSVPGQPVRVTLPDKAFVSSAVSHSHSGKHLGGFGVHGAAHLNAQSASFSPSLKSLPLSSSVHAATATLTSLQAKKASANALNTSQTQKWKICTICNELFPESAYSAHFEKEHQAEKVRAMAKYIMKIHNFTSKCLYCNRYLPSDSLLNHMLVHGLSCPHCHSTFHEVEKIVAHNRLAHPNEQGDQPTGSPLTFDLTLQQGNLKNVQLLVTTYNMKETPEAAAAAAAANQLSQNSAMPKPVKVSVRQPDTQSDSLVRNMSQSPVSQKKEVGKTLCPLCFTILKGPISDALAHHLRDSHQVLQTLHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVCQTPKGSKPITTGLRSPGAGSLKRELVTPDPSDPKRRKMVDQSRFYPTGFAEKPEEPIVLALDPKGYGDKSYEVRKAFLTAYFNRHPYPSQREVEKLAASLWLWKSDVASHFGNHRRLCDRDFTSRKPVVLLGFNMRLLSQIKHDMSFDDSCLFEVFDDEKSGYSRTSSFRLKSPIGFPADFIGSKQPLNTGQSSQSNCAFKTCPGSSSEPIAIDSDSDSELEVIPNENVSQHTPALRPSIVQSQTKGALLRESLRCERDVRANRSSPRVGPKVLDGSVSSSSPDEATWSGNMSSEESHYIPAGRFEVKGKKVGLLGR
Protein: Positive regulator of purine utilization (P49413)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Mediates the induction of a number of unlinked genes involved in purine utilization. Binds to the consensus sequence 5'-TCGGNNNNNNCCGA-3'.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Xanthine dehydrogenase
- Adenine deaminase
Sequence:
MLNPSTSDIHTSPTAVGNGRKRPHPIADSGSAMPSDPSAQQLPHPANESAAIPSIASSSSFRNVSACNRCRQRKNRCDQRLPRCQACEKAGVRCVGYDPITKREIPRSYVYFLESRVAYLEKVLMDNGIEYNEAVAFDEEEAVKIEAGYEAYAGSANGPAAGEIAAQDGSNDKSVRIKKEKNGPLGLEKASRYDHDPEVKQDSDAEDGWRIQNLVSNIGMVSVQGTSDPRYLGSTSGISFARVVFAAVKSSVPGNSSERGPSRPKERLPHSATGTEGSTTRDSFFGLQTRPMMKCAAFPDRELAERLADLYFEHANPQIPIVHRVDFMELLDRTYSVDEKSRSPRSLYFLNIVFAIGSGIIFEDKPAEDQKEGRDHSPSATKRQRLSSRQYQPEEYHASAIVHLESFLSTSPTTDGFGALEELQAVLLLASFALLRPVAPGLWYIVGVAMRLAVDLGLHYEDGAGIDGPENDNMNRTNNKDGEKAKLRIDDHERGRREWVRDFRRRLWWCCYSFDRLVSCCVGRPFGISDQAISTEFPSILEDKYITKSGIIKAPEGAPSYKHSAFHYFKLRVLQSEIQDVLQHQQARFARQRGPPGARSFMRLDVVSPFLQGFDSFRSWRRDVDRRLLEWKNSAPMPSENGVRFPLEFLELNYWQAVIMLYQQSLTVPAELADELSPAEDVSSPSFSQVEEDEHDIYYKVAEAGQKVIRIYRQMHRVRLVNYTYLATHHIFMAGISFLYAIWHSPYVRSRLTLDEVDFTVLAATSVLRDLMHKCPPAEACRDAFERMSKATVEMSLSTTGFGPQVELNRVQTSTSGSRQFNATQSRSRPYSRQQAEQRQRQSASRRQLQMRQSRPLPRFDMNLEDLFGDNRAVAERQGSGGMGKLAQPYPVSETSDPNFARPQSHRNPSMEYYGPFENPVSPQQPQPQPRYYYNNSPQQSGSPGSVVAASGIPPYQVTPTEQENPSGMGLDYLDYDPTGIERQLSLGSEENSDFKFQGGAQSLGHGAGHNFGIDLGFGMAVDFQHDWSENANYDLLEGYFFGGAGATGPGHGHGHGSGI
Protein: [histone H3]-lysine(4) N-trimethyltransferase (EC 2.1.1.354) (Q2MJQ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MEFVEVFDSPGKGRGLRATKEAWAGDVLFAEPPFASVVFDSQASSICHSCFRRQEKLQRCGQCRFAQYCDKTCQRAGWEEHKLECAAIKTYGKPPSENVRLAARILWRMDKQGSVVSDNQLTTLEDLEDHICDISEDDLKDFKVDIHNFLDYWPRNSKPHTVDSVSHILGVINCNGFMVSDQRGLQAVGVGLFPNLCLVNHDCWPNCTVILNNGKIELRALGKISAGEEVTVAYVDYLNVSADRQRLLKQQYFFDCTCKHCTEKIKDDLKMAGAEVDGVKVPEEQVKEVTEFSRQKLEKMEKARIEANYNEVVKICRECVEKQENVLADTHIYYLRVCCTLSEVLSYLQFFDEASEYARKMVDGYLKLYHPNNAQLGMATMRAGVTHWQAGFIEVAHGMICKAFAILMITHGPTHPITKDLEAMRMQTEMELRMFQQNEYVYHSMREAALKNQPMRMMAEPTNEGIKNLFRRK
Protein: Ubiquitin-conjugating enzyme E2-22 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein) (Ubiquitin-protein ligase) (P52486)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the covalent attachment of ubiquitin to other proteins.
Interaction partners:
- E1 ubiquitin-activating enzyme
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-ribosomal protein eL40 fusion protein
- GEO06356p1
- GH17761p
- Polyubiquitin
- CCR4-NOT transcription complex subunit 4
- Dorsal interacting protein 4
- Ubiquitin-conjugating enzyme E2-17 kDa
- Small ubiquitin-related modifier
Sequence:
MANMAVSRIKREFKEVMRSEEIVQCSIKIELVNDSWTELRGEIAGPPDTPYEGGKFVLEIKVPETYPFNPPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVAYQFKDKYDLFLLTAKHWTNAYAGGPHTFPDCDSKIQRLRDMGIDEHEARAVLSKENWNLEKATEGLFS
Protein: NorE protein (Q51666)
Organism: Paracoccus denitrificans
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU003376}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU003376}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MWVLIASELLVFAAGITAMAGVRLTDPAGFAAAQAQLHGWMAALNTAILVTSGFFAARAERACRRGDRRGARVGLALAALGGAGFLAVKAVEYAGDLRAGLGMESHPFFTFYYLLTGFHAAHVLFGIGVLALVAIRLRTEEVQAGAAFWHMVDLVWVLLLPPVYLLG
Protein: Monooxygenase, putative (Q38G02)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRVVIVGAGLSGLSLAAFLRRINIDCVVLEQSPFLRATYQPPYTLYANALSCFKAFELDDGFYTGDAISESHFGIQNERLQWLLRVRNRVVQLQALGQEDCVPLSTAPPANSDSTVSRRLAEELKQDLGCVPLRTTFSADYLRSILRKYVQEIRFNANVVDLRPHDGIKGGVHVVLDNGQTEWGDVVVGADGGHSTVRKLLYPDEYIGTSCRTLGMTQVDGYVELGDEPWPTGESPAEVWGKRRVLSCIPLQWDGRRHFAFSATLYDPPTEIVDVSKEMDPIELREVYRSLLRREFASFGGDITNTLSRAELAIPSELVEVPVMPRWYNKRAVLIGEAAHASLPSFLAQDASLCVEDAALLSTSLVDVPLCNDAGFEYAFRQFETVRRDRIEGYIRQSRRARRFTSLSHTWLRNGMLSVIPSLSLVWFQRWLANWSYSAQQLEVDPKIKMETAYRN
Protein: Receptor expression-enhancing protein 1 (Q8BGH4)
Organism: Mus musculus (Mouse)
Function: Required for endoplasmic reticulum (ER) network formation, shaping and remodeling; it links ER tubules to the cytoskeleton. May also enhance the cell surface expression of odorant receptors (By similarity).
Subcellular location: Membrane {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q9H902}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum {ECO:0000269|PubMed:24668814}. Note=A small proportion is detected at the cell surface. Localizes to endoplasmic reticulum tubular network. {ECO:0000269|PubMed:15550249, ECO:0000269|PubMed:24668814}.
Interaction partners:
- Atlastin-1
- Receptor-transporting protein 2
- Spastin
- Receptor-transporting protein 1
- Reticulon-2
- Protrudin
- Atlastin-3
- Atlastin-2
- Magnesium transporter NIPA1
- WASH complex subunit 5
Sequence:
MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGTGRSSGKHSQPKMSRSASESAGSSGTA
Protein: POU domain protein (A0A8I6A150)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MSPPGAAGRTGLSGAPRSVGELFQAQWTRACYTSLHGSWLQPFEGPPPPAAGEVQPGLSLCFCPSPLYQDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAMTRPTLPDPHLSHPQPSKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLTGLNPSAGSTMVGLSSGLSPALMGNNPLATIQGACCLMSPHCHQSCPLLGLEAPSPLLPQPCHPALPLTALLACSSPSVFGEGVRVLLLGSQWDRQEMGCSGRVHRGQGLPGLMYLQLSLSFSSPALASGGTLPLTSLDSSGNLVLGAAGAAPGSPSLVTSPLFLNHTGLPLLSAPPGVGLVSAAAAAVAATISSKSPGLSSSSSSSSSSSTCSEVAAQTSGGPGGPEAGSKAE
Protein: Methyltransferase (EC 2.1.1.-) (B0FDL8)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MDPVGLFCTGALLACGLYWFVCLLGPAEQKGKRAVDLSGGSISAEKVQDNYKQYWSFFRQPKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIEVKPGDRVLDVGCGVGGPMRAIAAHSRANVVGITINEYQVNRARLHNKKAGLDSLCEVVCGNFLEMPFKDNTFDGAYSIEATCHAPKLEEVYAEVFRVLKPGSLYVSYEWVTTDRYRGDNPEHVEVIQGIERGDALPGLRNYKDIAEVAKKVGFEVVKEKDLAKPPALPWWTRLKMGRIAYWRNHILVTVLASIGIAPKGTVDVHEMLFKTADYLTRGGDSGIFSPMHMILLRKPQVPPTQS
Protein: Actin-depolymerizing factor 6 (ADF-6) (AtADF6) (Q9ZSK2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9ZSK3}.
Interaction partners:
- Profilin-3
- Profilin-1
- Profilin-5
- Profilin-2
- Profilin-4
- Cyclase-associated protein 1
- Actin-11
- Actin-12
- Actin-7
- Villin-5
Sequence:
MSFRGLSRPNAISGMGVADESKTTFLELQRKKTHRYVVFKIDESKKEVVVEKTGNPTESYDDFLASLPDNDCRYAVYDFDFVTSENCQKSKIFFFAWSPSTSGIRAKVLYSTSKDQLSRELQGIHYEIQATDPTEVDLEVLRERAN