wanglab/gogpt-training-data huggingface dataset:
Protein: Probable UDP-arabinopyranose mutase 2 (EC 5.4.99.30) (Reversibly glycosylated polypeptide 2) (RGP2) (UDP-L-arabinose mutase 2) (UDP-glucose:protein transglucosylase 2) (UPTG 2) (Q8RU27)
Organism: Solanum tuberosum (Potato)
Function: Probable UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides (By similarity). Was initially shown to possess an autoglycosylating activity which is dependent on the presence of UDP-glucose and manganese (Probable).
Subcellular location: Secreted, cell wall {ECO:0000250|UniProtKB:P80607}. Cell junction, plasmodesma {ECO:0000250|UniProtKB:P80607}. Golgi apparatus {ECO:0000250|UniProtKB:P80607}. Note=Cell wall-associated, with highest concentrations on plasmodesmata. Also located in the Golgi apparatus (By similarity). {ECO:0000250|UniProtKB:P80607}.
Interaction partners:
Sequence:
MAGSSVTPTPLLKDELDIVIPTIRNLDFLEMWRPFFQPYHLIIVQDGDPSKIINVPEGFDYELYNRNDINRILGPKASCISFKDSACRCFGYMVSKKKYIYTIDDDCFVAKDPSGKDINALEQHIKNLLCPSTPHFFNTLYDPYREGADFVRGYPFSMREGAATAVSHGLWLNIPDYDAPTQLVKPRERNTRYVDAVMTIPKGTLFPMCGMNLAFDRELIGPAMYFGLMGDGQPIGRYDDMWAGWCIKVICDHLGLGVKTGLPYIWHSKASNPFVNLKKEYKGIYWQEEIIPFSQSATLPKDCTSVQQCYLELSKQVKEKLSTIDPYFTKLADAMVTWIEAWDELNPTGEGLAKLPSRTAPESRLH
Protein: Carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase III) (Carbonic anhydrase III) (CA-III) (P16015)
Organism: Mus musculus (Mouse)
Function: Reversible hydration of carbon dioxide.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P07451}.
Interaction partners:
- Cytochrome P450 2E1
- Adiponectin
- Complement factor D
Sequence:
MAKEWGYASHNGPDHWHELYPIAKGDNQSPIELHTKDIKHDPSLQPWSASYDPGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFTHFDPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFSSAENEPPVPLVGNWRPPQPVKGRVVRASFK
Protein: Protein PECTIC ARABINOGALACTAN SYNTHESIS-RELATED (EC 2.4.1.-) (O-fucosyltransferase 26) (O-FucT-26) (O-fucosyltransferase family protein) (Q9LIN9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Glycosyltransferase involved in the biosynthesis of pectic type-II arabinogalactans.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:27091363}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- At4g21108/At4g21108
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- At1g31410
- Subtilisin-like protease SBT2.6
- O-fucosyltransferase 36
- Disease resistance protein
- Putative clathrin assembly protein At4g40080
- Galactan beta-1,4-galactosyltransferase GALS1
- Probable xyloglucan galactosyltransferase GT11
Sequence:
MAELRHSSSLGSRSSSSPLRAAGDEDSSSPHVHDHSPNGGDDEDGRPRHPSRDRDRPIWFHSLFPFFGDDPRVSPQKNKISLLLILILAIASLISVYGIINHLNAPYLCKKDGIVLNCPHVKESPSPWENPLSATTSWKPCAERRIGGISDLPPENETNGYVFIHAEGGLNQQRIAICNAVAVAKIMNATLILPVLKQDQIWKDTTKFEDIFDVDHFIDYLKDDVRIVRDIPDWFTDKAELFSSIRRTVKNIPKYAAAQFYIDNVLPRIKEKKIMALKPFVDRLGYDNVPQEINRLRCRVNYHALKFLPEIEQMADSLVSRMRNRTGNPNPYMALHLRFEKGMVGLSFCDFVGTREEKVKMAEYRQKEWPRRFKNGSHLWQLALQKRKEGRCPLEPGEVAVILRAMGYPKETQIYVASGQVYGGQNRMAPLRNMFPNLVTKEDLAGKEELTTFRKHVTSLAALDFLVCLKSDVFVMTHGGNFAKLIIGARRYMGHRQKSIKPDKGLMSKSFGDPYMGWATFVEDVVVTHQTRTGLPEETFPNYDLWENPLTPCMCKA
Protein: Uncharacterized protein (Q57ZB8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase
- Uncharacterized protein
- Pre-mRNA splicing factor, putative
- Cell division control protein, putative
- MI domain-containing protein
- Splicing factor YJU2
- Pre-mRNA-splicing factor SYF1
- Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats domain-containing protein
- Pre-mRNA-splicing factor U5-Cwc21
- Uncharacterized protein
Sequence:
MLFDLAPHIDPKVLQRVAREKGYTLPVSEDSSEQRRQDASADLHAGLPLRFLATPEDVKRAYLPPPEGFEEAYVKKTDGGGLPEKRTTQPVARKRVRSGEGPAQVGVSDSATPAVISAAGATEVNTNVSTSVAANTLQANFDPSFERTNYLGRSFLEPPPSLQPRSHECRLPRQMKGSCDKHAAGIQQLQWLPPVGHLLFAADLKGEVRLYETFSSRRQCIASFVAHSQPVKSLEVTPDGETMSTGSVDGTVAMWDVEHGECRGVLTNSERLPCVQHLHHPLDPTSLILVALDRKVVLYDVRVSYQKYQREYTGHMGTIFNLSLLSGGKKLLTTAEDKTLRTWDFRVPVQIKQIADVSMHAITHVVRHPTEDMLVAQSLNNQALVFSDGGGGQVKLLRHRVFSGHTISGTRCQLAFSPDGRYLSSGDINGKLFIWSWATGELLRSFSAHTQTLVSHRWHPVEASRVVTSAWDGAIKTWA
Protein: Metal response element-binding transcription Factor-1, isoform C (A8JNP3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Copper transport protein
- Metallothionein-2
- Metallothionein-3
- P-type Cu
- GEO10380p1
- Metallothionein-4
- Metallothionein-1
Sequence:
MNDQEKQHQQQQQHYFHSEWKTTANSHGNSLSDSRDYDTNSSRNSLSGSPPVTSNCSSSGSLDFDRPLAQLLEPKLEADGLGIIHGDNYSIYGSQTAESTSGEQQVLNLGLTLDTGDAQATYGDLFGAQDQLTASQTHGHSQVVVSAAADNAFSLADQLTPLPITVIPITYHHTTENLSSSHSEVPLIASLSDITAQVFNLDDICFTLEYQFENQRLVQVQPPTVVSLSMVSSPNEAANPPINCDNDQGTGNSISRDSTSNSPAYFTIETSYVDEYDPNEPDEDEQLAHCIQPGVLHQDVDEEEVERQDENDQLMALAYESSDEALSRYRCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAFNTRYRLHAHLRLHNGETFNCELCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLQNKGRKKRPLKTQQTKCSDQEQKDPQQEEQEEEEFIKEDQPEMTLLNPGSHCSETTSTDSGVVLQTLTPQDHLSNVFILQGNEPLILPETSQAYQLSYAAEEEIPSPWIDAGVLVSKPIIPMAPLTDACVALPTEMPSFVNLKPTFGNAVSGNMGDPQPETMDVDPTVETSLPTPTLELNQPNIEELLKQDSFENEEDMETESLLNDILMTIDNNSALLQATLQQASQVPSDASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHGGDCGAAAAQQTTRTGAPTTTTTTTTMNSSGGKRICGSVVPTKKVSKRETEMNQNIEDVALLLQNLASMSSGGSSGGGGGCCGGGAVKPAPSGGGCCGEPKAPKPVNAGCGCARPSAPSSGGCCGSGVASTPKPTGGCCSGNQKPAPTATAASSPSCCCSGKGEVQEPPVISSASSAPAAAVKGNACTCKSPAEGVANGCCVVICIKTLQALRKVLTRRNLNLMLCPQQN
Protein: Exocyst complex component sec10 (O13705)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Interaction partners:
- Exocyst complex component sec15
- Exocyst complex component exo84
- Exocyst complex component sec8
- Exocyst complex component exo70
- Exocyst complex component sec6
- Exocyst complex component sec5
- Uncharacterized protein C17G8.12
- Protein transport protein sec9
- Cell division control protein 42 homolog
- GTP-binding protein rho3
Sequence:
MSTKNALNDSQIKLLNSLNDNKGIPSTEFVEKFAESLYETQNDGSKKLSSIDGSIKSFAACLHELNRLKSRVGDRIRDYASASKQVQNEYHQKSNHLREKFAQVLELSRHLEDNVNDMRSGLVDAGQELERAENNRKRILSSAELLRYYLEFRSGKPQTLMDFFRTNNHDKMLLCAQRTRQLLALANEVDLPDSSETLARIEKFSEFLETNFLKFFNNEYRKPNWKGMASFGTILQEFNGGASVVREFVNQHEFFIAADKVQSRQGLEQDPIWLILPDPTQKIPPLIQTLSSLFSELCSVIEGDCAVIKRVFPNPELVLQTFFQRIFGQSIQNRLEEVMEIAKGKSNLAYLRTLQTVVSSLRKLVADLKTILENRGFSVSDNSPLSLALNQYMEDLLVPFIEVDDYLKREEHSLRSLFRLSLYKYTSYKIRLETPEPGLLRSLMTPLQGNMVAPTGVHSQFNTKTEGFLLRIADIQENLIQSGSFITEDYITIEKNHSHLNSEKVYSFIGWHAEALNRASILISSQDLSVVISSLVNLLDKLIREDYVFKELSSIQSYISSHDKSKNLDLHYLVDIRECKKIMGYFSAYLMSIVIPFTGVTASSRRETVNILSSSISVIECAVNDVFYATVHALGDHLEIILSPYRQISYAMTEEQIDSSTELRQSMTRNVQNYLDYIKNLYHRLGPYDPSLLALKQKTATMLAAMLISFAFRSKVTAAGALLLQNDINFFHSTLTSWGIDTVDAKFKLILQLLSLLMVKIDVLPAVMQDKRKAGFSEMNIHEVLRLRFDLPENLKLQLNKEEALLPPKSS
Protein: Carboxymethylenebutenolidase homolog (F4HYC8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
- Putative cysteine-rich receptor-like protein kinase 32
- Kinesin-like protein KIN-14J
- Photosynthetic NDH subunit of subcomplex B 3, chloroplastic
- UPF0496 protein At3g19250
- AT5G58370 protein
- Oxysterol-binding protein-related protein 2B
- Pathogenesis-related family protein
- GTP-binding protein At2g22870
- Translocon-associated protein subunit alpha
- RNA polymerase sigma factor sigE, chloroplastic/mitochondrial
Sequence:
MAASLASLSSLAKAGAPRSLFNRHGSHRLPPPQIIPLASSIMFCQIKKHITTSFYRRGSSLKNIYALETSDGAINVEVDDDEEEEACELVNGTEVSVDGVEGYLLTAVKNNNGTGLLLLSDVFGFQDSATRDFAYRVACNGYNVLVPDLFRGDPWSKNRPKSEYEEWRRGHDPNRIRQDTTTFTKWMVEEFAAAGISKKLGVMGFCFGGGRVVDVLATDESGYFSTGVSFYGTRIDSAVAGDVKVPVLFIAGDRDPLCEVKGLYEIEEKIGEGSKVVVYEGRGHGFVHRPETPEDDRDAEEAFALMRNWLHHHLI
Protein: Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase 3 (HMG aldolase 3) (EC 4.1.3.17) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.112) (Regulator of ribonuclease activity homolog 3) (RraA-like protein 3) (Q9FH13)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
Interaction partners:
Sequence:
MAAFATAEACDSNAELISNGDLRALHPIFKIYGQRRCFSGPIVTLKVFEDNVLVRNQLETKGEGGVLVIDGGGSMRCALVGGNLGQLAQNNGWSGIVVNGCVRDVDEINDCDVGVRALGSNPLKSTKKGHGEKNVPVHIGGTLIRDGEWLYADSDGILISKTELSV
Protein: Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (Cytochrome P450-HFLA) (P450HLp2) (P24462)
Organism: Homo sapiens (Human)
Function: A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Metabolizes 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone, DHEA), a precursor in the biosynthesis of androgen and estrogen steroid hormones. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1), particularly D-ring hydroxylated estrone at the C16-alpha position. Mainly hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may play a role in atRA clearance during fetal development. Also involved in the oxidative metabolism of xenobiotics including anticonvulsants.
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane {ECO:0000305|PubMed:2492179}; Peripheral membrane protein.
Interaction partners:
- Cytochrome P450 2C9
- Cytochrome P450 2C8
- Cytochrome P450 3A5
- Cytochrome P450 2B6
- Cytochrome P450 2C18
- Cytochrome P450 1A1
- Cytochrome P450 1A2
- Cytochrome P450 2A6
- Cytochrome P450 4A11
- NADPH--cytochrome P450 reductase
Sequence:
MDLIPNLAVETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGNALSFRKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLLTEKPIVLKAESRDETVSGA
Protein: Pectin acetylesterase 7 (EC 3.1.1.-) (Q940J8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Subcellular location: Secreted, cell wall {ECO:0000305}.
Interaction partners:
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- Berberine bridge enzyme-like 26
- Subtilisin-like protease SBT1.5
- AT3g18860/MCB22_3
- Polyprenal reductase 2
Sequence:
MGRLKQCWSSLLVLAVLVIGTGAVPITYLQSAVAKGAVCLDGSAPAYHFDKGFGSGVNNWIVHMEGGGWCTDVASCNERKGTMKGSSKFMNKDFGFSGILGGKQSTNPDFYNWNRIKVRYCDGSSFTGNVEAVNPANKLFFRGARVWRAVVDDLMAKGMKNAQNAILSGCSAGALAAILHCDTFRAILPRTASVKCVSDAGYFIHGKDITGGSYIQSYYSKVVALHGSAKSLPVSCTSKMKPELCFFPQYVVPSMRTPLFVINAAFDSWQIKNVLAPTAVDKGKEWKNCKLDLKKCSAAQLKTVQGFRDQMMRALSPVHSTPSRGLFLDSCHAHCQGGSAASWSGDKGPQVANTRIAKAVGNWFYGRSAFQKIDCPSPTCNPTCPAISTED
Protein: General transcription factor IIH subunit 4 (Q38B82)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU364024}.
Interaction partners:
- DNA repair and transcription factor protein, putative
- DNA 5'-3' helicase
- [RNA-polymerase]-subunit kinase
- RNA polymerase-like protein
- TATA box-binding protein-like 1
- TFIIH basal transcription factor complex helicase/translocase XPB subunit
- DNA repair helicase/translocase XPB-R
- Plastid-encoded RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
Sequence:
MNPSYLNQILSYPQRESLISECPALALLCYQELVAAFRKGKRIADPLSLRDDVTVLLSIGSLHELTDRIFSAAPHESALPPLWCTLRKALECAWDPRGDGERQCELTMVGGKLRFYKKKCDRMPLAQSSMRNALNMSRTRIREVIACALSGSLEPLGGRRNEPIAALLQFSRLIPPPSEERVVTSEGLAFCMQPLQQQWWTLVSVVLDRALAIMSGKGVSRATLWQLLAVLFALNTSDYVYLFPSKDDDLEAFQLLARLSEVGLVYPLICNGEKCFVLSPHFHHAICWSSTPSLCTAALLDDTRGPSSRLRREDEDTIITETNFRLYAYTKNPDMLRILDQFAVKEVDVVGMVVCYRVTRASFASALAKGIGANHILQFLTVKAHPSMIKQSNSEAGDPSCPVLPAASVGFGNTSEYRQGNIIPQSFCDQLFTWERECRRLIFRHDVVLLKNIGKEQMEIILNCLSNSGEQHAVVHRESGTLAIEQEVYTRVLSNFITPD
Protein: Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828) (Q96JM3)
Organism: Homo sapiens (Human)
Function: Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.
Subcellular location: Nucleus {ECO:0000269|PubMed:21063390}. Chromosome {ECO:0000269|PubMed:21063390}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:21063390}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:21063390}.
Interaction partners:
- Mitotic spindle assembly checkpoint protein MAD2B
- Pogo transposable element with ZNF domain
- DNA repair protein RAD50
- Chromobox protein homolog 1
- Chromobox protein homolog 3
- Chromobox protein homolog 5
Sequence:
MEAFQELRKPSARLECDHCSFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAKLFHCHKCFFTSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEANKKLMEALEPPLEEQQI
Protein: SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23) (Q9UPE1)
Organism: Homo sapiens (Human)
Function: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:39073169}. Cytoplasm {ECO:0000269|PubMed:39073169}.
Interaction partners:
- Cell division cycle 5-like protein
- Serine/arginine-rich splicing factor 6
- Serine/arginine-rich splicing factor 5
- Serine/arginine-rich splicing factor 4
Sequence:
MSASTGGGGDSGGSGGSSSSSQASCGPESSGSELALATPVPQMLQGLLGSDDEEQEDPKDYCKGGYHPVKIGDVFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQAGAPPPSRSIVSTAPQEVLQTGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAATQAEDSGLRLDGGSGSTSSSGCHPGGARAGPSPASSSPAPGGGRSLSAGSQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP
Protein: NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) (NAD(P)H quinone reductase) (NAD(P)H: menadione oxidoreductase) (NADH-menadione reductase) (P9WHH7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: May contribute to virulence by increasing resistance to reactive oxygen intermediates. It can reduce 2,6-dimethyl-1,4-benzoquinone (DMBQ), 5-hydroxy-1,4-naphthaquinone (5-HNQ) and menadione. NADPH is the physiological reductant rather than NADH.
Interaction partners:
- Multifunctional 2-oxoglutarate metabolism enzyme
- Glycerol-3-phosphate dehydrogenase 2
- 3-methyl-2-oxobutanoate dehydrogenase subunit beta
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
- Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex
- Conserved protein
- 3-methyl-2-oxobutanoate dehydrogenase subunit alpha
- Probable dehydrogenase
- RNA pseudouridylate synthase
- Uncharacterized protein Rv1734c
Sequence:
MVTRIVILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGLRTELRRAPHLGFHIDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELIDSTPGLARHRIKATAADGSTSEHEADVVLVATGASPRILPSAQPDGERILTWRQLYDLDALPDHLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHVLPYEDADAALVLEESFAERGVRLFKNARAASVTRTGAGVLVTMTDGRTVEGSHALMTIGSVPNTSGLGLERVGIQLGRGNYLTVDRVSRTLATGIYAAGDCTGLLPLASVAAMQGRIAMYHALGEGVSPIRLRTVAATVFTRPEIAAVGVPQSVIDAGSVAARTIMLPLRTNARAKMSEMRHGFVKIFCRRSTGVVIGGVVVAPIASELILPIAVAVQNRITVNELAQTLAVYPSLSGSITEAARRLMAHDDLDCTAAQDAAEQLALVPHHLPTSN
Protein: Serine/threonine-protein phosphatase 7 (EC 3.1.3.16) (Q9FN02)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Phosphatase active on para-nitrophenylphosphate (pNPP) and on various phosphoproteins such as myelin basic protein. Seems to act as a positive regulator of cryptochrome signaling involved in hypocotyl growth inhibition and cotyledon expansion under white and blue light conditions. Confers thermotolerance. Required for heat shock mediated-signaling pathway that leads to the expression of heat shock proteins (HSPs).
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:11703093}.
Interaction partners:
- Protein DEHYDRATION-INDUCED 19 homolog 7
- CDPK-related kinase 1
- Protein MAIN-LIKE 1
- BTB/POZ domain-containing protein FBL11
- Calmodulin-1
- Protein MAINTENANCE OF MERISTEMS
- Heat shock protein 90-3
- TPR repeat-containing thioredoxin TDX
Sequence:
METVPPSPITWPDGGALTNDWVHGLMSCFEWSSWNLPPSQLPSLLPVNVFDSLVLTAHKILHKERNCVHIDDLDSVSNVVVVGDIHGQLHDLLFLLKDTGFPCQNRCYVFNGDYVDRGAWGLETFLVLLSWKVLMPDRVYLLRGNHESKYCTSMYGFEKEVLTKYGDKGKHVYRKCLGCFEGLPLASIISGRVYTAHGGLFRSPVLPKRTTRGKKNRRVVLLEPEPSSMKLGTLDELMQARRSVLDPPWEGSNLIPGDVLWSDPSMTPGLSPNEQRGIGLLWGPDCTEDFLKKYELKLIIRSHEGPDAREKRTGLGGMDNGYTIDHNVESGKLITIFSAPDYPQFQATEERYKNKGAYIILQAPDFSDPQFHSFEAVKPRPKAHPYYDFENVIDSDDEMDKSAMDTNNEQPNS
Protein: Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (Renin/prorenin receptor) (Q7T0S3)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Cell projection, dendritic spine membrane {ECO:0000256|ARBA:ARBA00029429}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00029429}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000256|ARBA:ARBA00029432}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00029432}. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000256|ARBA:ARBA00029430}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00029430}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000256|ARBA:ARBA00029428}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00029428}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004352}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004352}.
Interaction partners:
- Uncharacterized protein.
- V-type proton ATPase subunit S1
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase proteolipid subunit
- V-type proton ATPase proteolipid subunit
- Uncharacterized protein.
- Uncharacterized protein.
- V-type proton ATPase subunit H
- V-type proton ATPase subunit H
Sequence:
MLRLVLVALVVAVSSADFTVLKSPQYQIFQEGKWPVPGDRIPDVISLSMGFSVEEGLDWPGLGVGNLFQRPRSTVLVTVTGVNKLPLSGNGMSYPVENAVPYSLDSVVNSVHSVFSEEMPVVLQLAPIEERVYMVGKANTVFEDLSVTLRQLRTRLEQDNSIIQSLPVSSLYKNDETDRLFLSELQVLQDIITLLSGHKHLAKDNVPDIYSLELTGLEEIKKRYGEESAKFKDAVKILSDFLQKFADDMYSIYGGNAIVEVVAVESFEIPLVRRSRSILASEAISNPGSPYNLAYQYNFDYAVIFNIILWIMIGLALAVIAISYSLWNMDPGYDSIIYRMTNQKIRMD
Protein: Nucleoprotein (Protein N) (Nucleocapsid protein) (O89339)
Organism: Hendra virus (isolate Horse/Autralia/Hendra/1994)
Function: Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (By similarity).
Subcellular location: Virion. Host cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MSDIFDEAASFRSYQSKLGRDGRASAATATLTTKIRIFVPATNSPELRWELTLFALDVIRSPSAAESMKIGAAFTLISMYSERPGALIRSLLNDPDIEAVIIDVGSMLNGIPVMERRGDKAQEEMEGLMRILKTARESSKGKTPFVDSRAYGLRITDMSTLVSAVITIEAQIWILIAKAVTAPDTAEESETRRWAKYVQQKRVNPFFALTQQWLTEMRNLLSQSLSVRKFMVEILMEVKKGGSAKGRAVEIISDIGNYVEETGMAGFFATIRFGLETRYPALALNEFQSDLNTIKGLMLLYREIGPRAPYMVLLEESIQTKFAPGGYPLLWSFAMGVATTIDRSMGALNINRGYLEPMYFRLGQKSARHHAGGIDQNMANKLGLNSDQVAELAAAVQETSVGRQDNNMQAREAKFAAGGVLVGGGEQDIDEEEEPIEHSGRQSVTFKREMSMSSLADSVPSSSVSTSGGTRLTNSLLNLRSRLAAKAIKESTAQSSSERNPPNNRPQADSGRKDDQEPKPAQNDLDFVRADV
Protein: Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit) (Q01081)
Organism: Homo sapiens (Human)
Function: Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Subcellular location: Nucleus {ECO:0000269|PubMed:15096518}. Nucleus speckle {ECO:0000269|PubMed:15096518, ECO:0000269|PubMed:25311244}.
Interaction partners:
- Splicing factor U2AF 65 kDa subunit
- Serine/arginine-rich splicing factor 2
- Serine/arginine-rich splicing factor 1
- Splicing factor 1
- Serine/arginine-rich splicing factor 3
- C3H1-type domain-containing protein
- Heterogeneous nuclear ribonucleoprotein M
- RNA-binding protein 39
- Splicing factor, proline- and glutamine-rich
- Serine/arginine-rich splicing factor 5
Sequence:
MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF
Protein: GEO07291p1 (Odorant-binding protein 99c, isoform A) (RE07893p) (Q9VAI9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- GH20802p
- GEO11742p1
- Apolipophorins
- General odorant-binding protein 56d
- Niemann-Pick type C-2g, isoform A
- GEO09367p1
- GH14572p
- MIP26555p1
Sequence:
MLKYLIVALALCAVAHADDWTPKTGEEIRKIRVDCLKENPLSNDQISQLKNLIFPNEPDVRQYLTCSAIKLGIFCDQQGYHADRLAKQFKMDLSEEEALQIAQSCVDDNAQKNPTDVWAFRGHQCMMASKIGDKVRAFVKAKAEEAKKKAA