wanglab/gogpt-training-data huggingface dataset:
Protein: diguanylate cyclase (EC 2.7.7.65) (Q9HXT9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Chemotaxis protein CheW
- Chemotaxis protein CheA
- CheW-like domain-containing protein
- Probable chemotaxis transducer
- Protein-glutamate methylesterase/protein-glutamine glutaminase 3
- Probable biofilm formation methyltransferase WspC
- Cyclic di-GMP phosphodiesterase RocR
- EAL domain-containing protein
- FimX
- Cyclic di-GMP phosphodiesterase PA4781
Sequence:
MHNPHESKTDLGAPLDGAVMVLLVDDQAMIGEAVRRSLASEAGIDFHFCSDPQQAVAVANQIKPTVILQDLVMPGVDGLTLLAAYRGNPATRDIPIIVLSTKEEPTVKSAAFAAGANDYLVKLPDAIELVARIRYHSRSYIALQQRDEAYRALRESQQQLLETNLVLQRLMNSDGLTGLSNRRHFDEYLEMEWRRSLREQSQLSLLMIDVDYFKSYNDTFGHVAGDEALRQVAGAIREGCSRSSDLAARYGGEEFAMVLPGTSPGGARLLAEKVRRTVESLQISHDQPRPGSHLTVSIGVSTLVPGGGGQTFRVLIEMADQALYQAKNNGRNQVGLMEQPVPPAPAG
Protein: Histone H2A.2 (P04912)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- FACT complex subunit SPT16
- Histone H4
- Histone H2A.1
- Histone H3
- Histone H2B.2
- Histone H2B.1
- FACT complex subunit POB3
- Nucleosome assembly protein
- Histone H1
- Histone H3-like centromeric protein CSE4
Sequence:
MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKTAKASQEL
Protein: Hydroxyproline-rich systemin A [Cleaved into: HypSysA I (TobHypSysA I); HypSysA II (TobHypSysA II)] (Q93WP8)
Organism: Nicotiana tabacum (Common tobacco)
Function: Activates a lipid-based signal transduction pathway in which linolenic acid is converted to jasmonic acid, a potent activator of defense gene transcription, including proteinase inhibitors.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MRVLFLIYLILSPFGAEARTLLENHEGLNVGSGYGRGANLPPPSPASSPPSKEVSNSVSPTRTDEKTSENTELVMTTIAQGENINQLFSFPTSADNYYQLASFKKLFISYLLPVSYVWNLIGSSSFDHDLVDIFDSKSDERYWNRKPLSPPSPKPADGQRPLHSY
Protein: guanylate kinase (EC 2.7.4.8) (F4J3E9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGEAPAFFVDHLENGYTNGFGVKSEPKNRDTSVLIGDRSFVIGGNHEGNPLFLGVQIHDKVTNKWSSPSVLGTGPKPCKGYSAIVLPKGRILVIKKGSASDDSIWFLEVDTPFIREQKKLLGREVVAWSKGVRGNAEKPIVISGPSGVGKGTLISMLMKEFPSMFGFSVSHTTRAPRCMEKNGVHYHFTDKTVMEKEIKDGKFLEFASVHGNLYGTSIESVEVVTDSGKRCILDIDVQGARSVKASSLDAIFIFVCPPSMKELEDRLRARGTETEEQIQKRLRNADAEIKAGKSSGIFEHKLYNDNLEECYKTLKNLLGINDLAPVNGVEAVEGINLPKEHTVTKMDDKILIQETGEGTKNKMIVLDLSSINGGAPGRTRGIVLDTVKSS
Protein: Meis homeobox 1 (F7EL40)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
FVMQYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLVRADPSLPSLSVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDVTRAANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
Protein: Small ribosomal subunit protein uS12cz/uS12cy (30S ribosomal protein S12, chloroplastic) (P62126)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity).
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS7cz/uS7cy
- Small ribosomal subunit protein bS16cz
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS8c
- Small ribosomal subunit protein uS14m
- Ribosomal protein S7.
- Large ribosomal subunit protein uL16c
- Large ribosomal subunit protein uL2cz/uL2cy
- Large ribosomal subunit protein bL36c
Sequence:
MPTIKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
Protein: Nesprin-4 (KASH domain-containing protein 4) (KASH4) (Nuclear envelope spectrin repeat protein 4) (Q8CII8)
Organism: Mus musculus (Mouse)
Function: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology, by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.
Subcellular location: Nucleus outer membrane {ECO:0000269|PubMed:19164528, ECO:0000269|PubMed:23348741}; Single-pass type IV membrane protein {ECO:0000269|PubMed:19164528, ECO:0000269|PubMed:23348741}. Note=Localization at the nucleus outer membrane location requires the presence of SUN1.
Interaction partners:
- SUN domain-containing protein 1
- SUN domain-containing protein 2
- Nesprin-3
- Nesprin-1
- Nesprin-2
- Protein KASH5
- Kinesin-1 heavy chain
- Plectin
- SUN domain-containing protein 3
- Sperm-associated antigen 4 protein
Sequence:
MALVPPLGREFPPEPVNCPLAAPRELDVVGGTICPAPEEETSRPEQVQASLGLPEHCMGELKSTESATSPSRLPLASSHEHQDGGKPCEHSDSGLEVLEAEQDSLHLCLLRLNFRLQDLERGLGSWTLAHNRIVQMQALQAELRGAAERVDALLAFGEGLAERSEPRAWASLEQVLRALGTHRDTIFQRLWQLQAQLISYSLVLEKANLLDQDLEVEGDSDGPAAGGVWGPWAPSTFPTPAELEWDPAGDVGGLGPSGQKISRIPGAPCELCGYRGPQSSGQGLEDLLSLGLGHRKHLAAHHRRRLRKPQDRKRQVSPSLPDAMLEVDRGVPAPASKRPLTLFFLLLFLLLVGATLLLPLSGVSCCSHARLARTPYLVLSYVNGLPPI
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q8IHB0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQRRERQASGGGPQTTTAGPSAGNVANATTALAGGKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTGKTMET
Protein: Putative F-box protein At5g39480 (Q9FLY8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MMNKESFGACLLLTLPEDVFAVISRFLSPSDICNLILCGKSLPALVDTEKMWLVQCEEVKVLPLLEIVQWRIGISSYKALCRFLVEVVKPLLGIWVQQNPELGNVVYVMPGFLSVVGCRIIPQKVAPSWIQEDRVKWSPVFEIICGFDGSNGFFLHGRDKEGSCLYPGFVMGIEKSCNVLQLDVVPRQEKSSCNEIERGASREEGEIPFWMLAFSDRKNLLNIVTSHVSLHVVEPLNEMLFPTLKYDEAMLVERRTILLKMHKFGGNWKNMNLEEDDQLCYNPMQVKINEMLENLGDDYFFDEEELIEVTPTENTNVLGESSSSKNTTPSQSEIRVSNRQSFLSSGDTFGLGLTASYSEMSYYKGWPYMHFHHFLLYKLPVKKAVDQEAYAGLWGGTIGCPAGKCPKGKTEKSLYLLMLTYEESEEHSERVLIGTKILEGKRYVRHPNGTAMFVVKIDTPSLDPFPVDANETHFENSYSGEGIAEGYSFRYTGSKPGSLFVITNDLLAFVWKETKVVITLQRLNLTEILKKGLGSCVPPLPPSKNFTYMRRSFINEFTKLSTDSSYSE
Protein: Hemotin (A0A0B4K753)
Organism: Drosophila melanogaster (Fruit fly)
Function: Negatively regulates early endosome maturation by binding to and repressing the activity of 14-3-3zeta which prevents the 14-3-3zeta-mediated activation of phosphoinositide 3-kinase Pi3K68D. This, in turn, inhibits the Pi3K68D-mediated conversion of phosphatidylinositol to phosphatidylinositol-3-phosphate and prevents progression of early endosomes through the maturation process which regulates subsequent steps of phagocytic processing.
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:27015288}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized protein, isoform B
- IP01563p
- UPF0184 protein CG14818
Sequence:
MDCFKVFEVVFQSEINPLLLIPAVATIALTLCCYCYHGYQWIRDRRTARIEEQQAQLPLPLSRISITPGCSMVATTKLTHSRNSVDIY
Protein: Meiotic recombination protein DMC1 homolog A (OsDMC1A) (OsDMC1) (RiLIM15A) (Q7GBF8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Recombinase that may participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (Probable). Exhibits DNA-dependent ATPase activity when bound to single-stranded DNA (ssDNA). Mediates renaturation of homologous complementary strands as well as assimilation of single strands into homologous supercoiled duplexes leading to D-loop formation. Binds circular single-stranded DNA (ssDNA) and circular double-stranded DNA (dsDNA) in vitro. Catalyzes DNA homologous renaturation and DNA strand exchange. The rates of these activities are dependent on the state of ATP hydrolysis. Forms helical filaments along ssDNA and dsDNA, and promotes strand exchange between ssDNA and dsDNA with long DNA substrates of several thousand base pairs. The presence of the replication protein A is not required for this activity. Seems to be required for homologous pairing and subsequent chromosome segregation during male meiosis. May be not directly required for homologous pairing during male meiosis. Required for synaptonemal complex assembly and crossover formation. Functions redundantly with DMC1B.
Subcellular location: Nucleus {ECO:0000269|PubMed:26960731}.
Interaction partners:
- Os02g0562100 protein
- Os01g0164900 protein
- Os01g0164800 protein
- Os01g0660500 protein
- ATP-dependent DNA helicase
- Crossover junction endonuclease MUS81
- Kinetochore protein NDC80
- Os03g0639700 protein
- Os09g0104200 protein
- Double-strand break repair protein MRE11
Sequence:
MAPSKQYSEGGQLQLMDAERIEEEEECFESIDKLISQGINSGDVKKLQDAGIYTCNGLMMHTKKSLTGIKGLSEAKVDKICEAAEKLLSQGFITGSDLLIKRKSVVRITTGSQALDKLLGGGIETLCITEAFGEFRSGKTQLAHTLCVSAQLPIHMHGGNGKVAYIDTEGTFRPERIVPIAERFGMDANAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFSGRGELAERQQKLAQMLSRLTKIAEEFNVAVYITNQVIADPGGGMFITDLKKPAGGHVLAHAATIRLMLRKGKGEQRVCKIFDAPNLPEGEAVFQVTSGGIMDAKD
Protein: NAD(P)H-dependent FMN reductase LOT6 (FMN reductase LOT6) (EC 1.5.1.39) (Azoreductase LOT6) (FMN reductase [NAD(P)H]) (Low temperature response protein 6) (Q07923)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has several reductase activities that are NAD(P)H-dependent and involve FMN as a cofactor, ferricyanide being the best substrate for reduction. May be involved in ferric iron assimilation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Protein LOT5
- Riboflavin kinase
Sequence:
MKVGIIMGSVRAKRVCPEIAAYVKRTIENSEELIDQKLKIQVVDLQQIALPLYEDDDELIPAQIKSVDEYADSKTRSWSRIVNALDIIVFVTPQYNWGYPAALKNAIDRLYHEWHGKPALVVSYGGHGGSKCNDQLQEVLHGLKMNVIGGVAVKIPVGTIPLPEDIVPQLSVHNEEILQLLASCIETTRNK
Protein: NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A) (H8W3Y1)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MKVFAVLALVVASVLADTLPSVTLCPPETQTIFVLQHNTTVGARIRTIPTSNLAECSDHCSASLDCQGVEFKDGSCAVFRAGSEKATAGSQLLTKTCVKSDRVCQSPFQFDLFEQRILVGFAREVVPAANIQICMAACLNAFDTFGFECESAMFYPVDQECILNTEDRLDRPSLFVEESDDTVIYMDNNCAGSQCYPPYITQYIAVEGKQLKNELDRIINVDLDSCQALCTQRLSISSNDFNCKSFMYNNKTRTCILADERSKPLGRADLIATEGFTYFEKKCFASPNTCRNVPSFKRVPQMILVGFAAFVMENVPSVTMCLDQCTNPPPETGDGFVCKSVMYYYNEQECILNSETRESKPELFIPEGEEFLVDYFDITCHLKQEKCPTGQHLKAIRTINAALPEGESELHVLKASAAKGIKECVAKCFGLAPEKCRSFNYDKKTKSCDLLYLDGHNTLQPQVRQGVDLYDLHCLAVENDCSANKDDALFSRYLHTKQRGIPAKVYKVVSLNSCLEVCAGNPTCAGANYNRRLGDCTLFDAIDDDAEINEHTDFYKNLCVTKEIDTGASAAANVPETKHRVSGTVVEGKDSKSQLLATKKVKKPTIKNTEHRRAPESTVPIGPPVEVKAEAIQTICNYEGIKVQINNGEPFSGVIFVKNKFDTCRVEVANSNAATLVLGLPKDFGMRPISLDNIDDNETGKNKTKKGEETPLKDEIEEFRQKRQAAEFRDCGLVDLLNGTYKSTVVIQTNNLGIPGLVTSMDQLYEVSCDYSSMLGGRVQAGYNMTVTGPEANLIQPRGKIELGNPVLMQLLNGDGTEQPLVQAKLGDILELRWEIMAMDDELDFFVKNCHAEPGVAGGKAGAGEKLRLIDGGCPTPAVAQKLIPGAIEIKSSAVKTTKMQAFRFDSSASIRVTCEVEICKGDCEPVECALTGGVKKSFGRKKREVSNNIEEFETNRYLIPRRSHATTSIVIIDPLQQVCTKVNEPVAMSRASTLDLLREDAHEVQMIEEGSICLNSVTVFAIFGTLAVLILGQTVVIAHYAVRRFSSEKTA
Protein: At1g31410 (Putrescine-binding periplasmic protein-like protein) (Q66GJ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
Interaction partners:
- At4g21108/At4g21108
- rRNA-processing protein EFG1
- Ubiquitin C-terminal hydrolases superfamily protein
- Protein REGULATOR OF FATTY ACID COMPOSITION 3
- Subtilisin-like protease SBT2.6
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Large ribosomal subunit protein eL31y
- Disease resistance protein
- Putative clathrin assembly protein At4g40080
- Protein PECTIC ARABINOGALACTAN SYNTHESIS-RELATED
Sequence:
MATAAIISVKPPASFYCGGNRRDGGRGITIARVSRDERFHERIVGLSASTVLFIGLSSLRVCSPASARILPPPIVVTENEINTETVAGEENLNEVEDEEKLEADFEAYKSKVYSLTVPLKLVALRGSVPPSWIKEFMSSQGKRVRLKTQFRGNLEEIFFDLSKPSKNGKKGAASTAAADMISIGDSWLSFAIKEKLIEPMKGIEDQDWYKGLSDKWKIYLRRNYAGEKAPDGETWAVPYRWGTMVIAYKKSKFQNYKLAPIEDWADLWRPELAGRIAMVNSPREVVGAVLKYMRASYNTTDLDSQVPGGRLAVEKNLASLMKQIRLFDSNNYLKAFNVGDVWVTVGWSSDVIPVAKRMSNVTVIVPKSGATLWADLWAIPAVSDSGKEAEQRGGRVRGPSPLINQWIEFCLQPARSLPFTREVIPGASPSALDGPLVTEPEKTKKDRTKLDTNLVTGVPPPEILSKCEFLEPLPEATLSEYRLLIETVRKQSQRPGLVEKLKDIVSIKVRGFRAKLDSEMNKNI
Protein: U-box domain-containing protein 45 (EC 2.3.2.27) (Plant U-box protein 45) (RING-type E3 ubiquitin transferase PUB45) (Q9C7G1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as an E3 ubiquitin ligase.
Interaction partners:
- Probable aspartyl protease At4g16563
- At1g14330/F14L17_7
- BTB/POZ domain-containing protein At2g30600
- Probable CCR4-associated factor 1 homolog 5
- F-box/kelch-repeat protein At1g15670
- F-box protein PP2-A14
- Kelch repeat-containing protein At3g27220
- RING-H2 finger protein ATL79
- E3 ubiquitin-protein ligase SGR9, amyloplastic
- RING-type E3 ubiquitin transferase
Sequence:
MDVNEVEENFFAPGDAKLHGKMCNALSVIYCKIMSIFPSLEAARPRSKSGIQALCSLHVVLEKVKNILRHCTESSKLYLAITGDSVVLKFEKAKSSLTDSLRRVEDIVQQSIGSQLLEILMELENTEFSLDPAEKEIGDQIIGLLQQGGNFESSSDNNELEVFHQAATRLGITSSRAALTERRCLKKLIERARMEDDKRKESIVAYLLHLMRKYSKLFRSEIWDDNDSQGSSSLPCSPTIQGSIDDAHGRAFDRQLSKLSSFNFRSCNNNRRSSQMSVPPEELRCPISLQLMYDPVIIASGQTYERICIEKWFSDGHNTCPKTHQQLSHLCLTPNYCVKALISSWCEQNGVQVPDGPPESLDLNYWRLALSVSESTDTRSAKRVGSCKLKDVKVVPLEESGTIKEEACESEYQEDQVTLVERCTELLTTLTDVDTLRKKCRVVEQIRVLLKDDEEARILMGENGCVEALLQFLGSALNENNASAQKVGAMALFNLAVDNNRNKELMLASGIIPLLEEMLCNPHSHGSVTAIYLNLSCLEEAKPVIGSSLAVPFMVNLLWTETEVQCKVDALHSLFHLSTYPPNIPCLLSADLVNALQSLTISDEQRWTEKSLAVLLNLVLNEAGKDEMVSAPSLVSNLCTILDTGEPNEQEQAVSLLLILCNHSEICSEMVLQEGVIPSLVSISVNGTQRGRERAQKLLTLFRELRQRDQTHLTEPQHTEVTSPEDGFSVASAAVTETKPQCKSASRKKMGRAFSFLWKSKSFSVYQC
Protein: Serine/threonine-protein kinase PSK2 (EC 2.7.11.1) (PAS kinase 2) (Q08217)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Serine/threonine-protein kinase involved in the control of sugar metabolism and translation. Phosphorylates UGP1, which is required for normal glycogen and beta-(1,6)-glucan synthesis. This phosphorylation shifts glucose partitioning toward cell wall glucan synthesis at the expense of glycogen synthesis. Phosphorylates also the glycogen synthase GSY2 and the translation factors CAF20, TIF11 and SRO9.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- UTP--glucose-1-phosphate uridylyltransferase
Sequence:
MTYPVSAAAPADISYSKNTPLVGLSKPPCLYQHASSSVDSFSSTFSDDDRSDLVAVPNESPHAFSYNPISPNSLGVRLTILRRSLEIMVNSPDILHELKKKAPVIAYPPSLRHTRNLTETATLSASRDPLNGSLISPLVSNMPSPASRPVIQRATSLMVLPDNDTASKLNPAKSELENLLFLLNLALENNSFERASDLHMLSLLNIKKINFDSDIQKSETLKKVLLDSLAEPFFENYKKFPHKDLGSKSQYNEYEEKHDDIVSLADIKPQQDYSRILHPFTSAKNSGPEAIFTCSQQYPWNFKAANDLACLTFGISKNVIKALTLLDLIHTDSRNFVLEKIMNAEDDNQEIVFTGETIPIVQPNSTSNNNVPNLIWASLWAKRKNGLLVCVFEKTPCDYIDVMLNLRDFSVDSIIDTTHFLENFDKKKQQESTSPMTEKKTVKFANEIHDIGSVSHSLSKLIDDVRFGKVFSADDDLLPLSIRVANHVNEERYFTLNCLSENIPCAVTTSVLENEIKLKIHSLPYQAGLFIVDSHTLSLLSFNKSVAKNMFGLRLHELAGSSVTKLVPSLADMISYINKTYPMLNITLPENKGLVLTEHFFRKIEAEMHHDKDSFYTSIGLDGCHKDGNLIKVDVQLRVLNTNAVLLWITHSRDVVIENYTTVPSQLPMLKENEIDVVGSRGSSSASSKKSSEKIPVNTLKAMADLSISSAETISNSDDEVDLNQVNEKLRETSCGKVRGIESNDNNNYDDDMTMVDDPELKHKIELTKMYTQDKSKFVKDDNFKVDEKFIMRIIEPINGEEIKKETNELDKRNSTLKATYLTTPEANIGSQKRIKKFSDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWLKI
Protein: Arrestin domain-containing protein 15 (P30647)
Organism: Caenorhabditis elegans
Interaction partners:
- Arrestin C-terminal-like domain-containing protein
- Arrestin C-terminal-like domain-containing protein
- Arrestin C-terminal-like domain-containing protein
- Arrestin C-terminal-like domain-containing protein
- Arrestin C-terminal-like domain-containing protein
- Arrestin C-terminal-like domain-containing protein
- Arrestin C-terminal-like domain-containing protein
- Arrestin-like N-terminal domain-containing protein
- Arrestin C-terminal-like domain-containing protein
- Arrestin C-terminal-like domain-containing protein
Sequence:
MPEVSNGRRPSVATFLRQFASTIIPLVNVKQSMPTTQINIVLAEPRCMAGEFFNAKVLLDSSDPDTVVHSFCAEIKGIGRTGWVNIHTDKIFETEKTYIDTQVQLCDSGTCLPVGKHQFPVQIRIPLNCPSSYESQFGSIRYQMKVELRASTDQASCSEVFPLVILTRSFFDDVPLNAMSPIDFKDEVDFTCCTLPFGCVSLNMSLTRTAFRIGESIEAVVTINNRTRKGLKEVALQLIMKTQFEARSRYEHVNEKKLAEQLIEMVPLGAVKSRCRMEFEKCLLRIPDAAPPTQNYNRGAGESSIIAIHYVLKLTALPGIECEIPLIVTSCGYMDPHKQAAFQHHLNRSKAKVSKTEQQQRKTRNIVEENPYFR
Protein: Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (Citrin) (Solute carrier family 25 member 13) (Q9QXX4)
Organism: Mus musculus (Mouse)
Function: Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (By similarity). Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9UJS0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9UJS0}.
Interaction partners:
Sequence:
MAAAKVALTKRADPAELKAIFLKYASIEKNGEFFMSPHDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQIFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNAKTGKVSAIDFRDIMVTIRPHVLTPFVEECLVAAAGGTRSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGNRKDVEVTKEEFALAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGMLPFNLAEAQRQQKASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYNGVTDCFRKILREEGPKALWKGVAARVFRSSPQFGVTLLTYELLQRWFYVDFGGVKPVGSEPVPKSRITLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFKPSASTSKVTAGDS
Protein: U6 snRNA phosphodiesterase 1 (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) (Q9VHB3)
Organism: Drosophila melanogaster (Fruit fly)
Function: 3'-5' RNA exonuclease that trims the 3' end of oligo(U) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate. Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03040}.
Interaction partners:
- Pre-mRNA-processing factor 19
- Sphinx2, isoform B
- Pre-mRNA-splicing factor syf1 homolog
Sequence:
MALVDYGGSSSSASEDEDCTENIQTPALITLKRPALPKAATLLGPKKPKPEEFVEDVVDDPAEHGGRMRSFKHERGNWATYVYVPATACVDQLEEFQTEAIARLEPHLELQPNESLHLSLSRTVVLQYHQIDEFSRSLQSALNSSAGFAATLQGLRIYTNEERTRTFIAAPLDAAFVEKMTAILQPIDQVMLDYRLQQFYDPASFHVSLLWCVGDQETLLNEKLTELKELLDDQDKLCLAVNEVHLKCGNKDFTYSLK
Protein: Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) (P26640)
Organism: Homo sapiens (Human)
Function: Catalyzes the attachment of valine to tRNA(Val).
Interaction partners:
- Lysine--tRNA ligase
- Elongation factor 1-delta
- Bifunctional glutamate/proline--tRNA ligase
- von Willebrand factor A domain-containing protein 7
- Leucine--tRNA ligase, cytoplasmic
- Tyrosine--tRNA ligase, cytoplasmic
- Aspartate--tRNA ligase, mitochondrial
- Elongation factor 1-alpha 1
- Elongation factor 1-beta
- Probable arginine--tRNA ligase, mitochondrial
Sequence:
MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPALEQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISLQQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVADEATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARELGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALFQKML
Protein: Geranylgeranyl pyrophosphate synthase (Q5GRP9)
Organism: Wolbachia sp. subsp. Brugia malayi (strain TRS)
Interaction partners:
- Isoprenyl transferase
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
- Geranylgeranyl pyrophosphate synthase
- Peptidyl-prolyl cis-trans isomerase
Sequence:
MLDKTTKNLLITEINKILPEDSQNRLISAVRYVLLAPAKHIRPFLVVASSQVFNVEIERVISIAMAVECIHTYSLIHDDLPCMDNSDTRRGQLSCHKRFDKATAVLAGDALLTLAFEILSSLNEGSNKRCEIIKALSQAIGAKGMVGGQILDIKTALHVIQHHDYLDPESSVINEHTRQLCNKNRTLGSCAKITPDSKIKEIHLMKTAKLFAASCEIGAIIGSATDKQRRALYNYGVNLGLIFQAKDDIRDYKQDEVNNLMSMLSKSEIENYIDNLFKQALDNLGELSGDTNYLYNLLNQVKRDD
Protein: Sll1252 protein (P74082)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- Photosystem II CP47 reaction center protein
- CyanoQ
- Protein Thf1
- Photosystem II reaction center Psb28 protein
- Sll1390 protein
- Photosystem II lipoprotein Psb27
- Photosystem I reaction center subunit III
- Photosystem I reaction center subunit II
- Photosystem II reaction center protein Z
- Photosystem II extrinsic protein O
Sequence:
MLPREALLKGAPDREAIARVIDQAEQALRTWEVVVSDFCAPPLIAEIQTRFDSLTELHFLPWGGYPQAERQRLAIARAEIPLETEQIPLTALDVAGNFLFDPASHRDFLGALLGTGLVREKVGDIILLGERGAQAIVVPEVAEFISLHLTQVRTVPVKAKAIALEELKIRPPKTKEMTTVEASLRLDAIASAGFGLSRSKMADAVTQGNVQVNWKPVTQSSYALKAGDLVTYRGKGRLEIGEITVTKKERYRIQLTRYL
Protein: Kinetoplastid kinetochore protein 6 (Q585C6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHSILPYTLDPERMTGCRKMNTINPYDASVTGPESSARDLDVIRNHLLQEWDRRTTSTVLFNPAAEIDIRSWDLSWTERESHWEENVAQCISPEEVEGLLPAKWFGYNTSSDVDETLARVCKLCTALVDKFVELSKGDNANQSTAKWRQHQAMLARISAVVELLEEAVGETLSMYDLRDPQTVRCLWERMDDEDRRKVASVLGAR
Protein: Common salivary protein 1 (Q63015)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MLPLLILAFLGTPAVLTQSRYHGSETGKHFCIVAPEGEPVTGIWASLKNNILSSIRLKFGNNWSQEYGSSGRAEIEVKLNPDETVLGFSGSFYIFMHQIIITTSQPRELIIGPLTGRYVYTSYPENPNHVFRGICGYYVTGGLKGMRYLWGNVNGTCTE