wanglab/gogpt-training-data huggingface dataset:
Protein: Aspartic endopeptidase (Q5AH56)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MNKTISLLYSLLILIIQVGAARKDAQTTPIIVAPEAKTTTTTSSSLSSSTTTTTGKPNNGKKSPGKPTTDSNDIVQITLQRPTTPPLLSQETQLKGSGDTKAGQAISGSTTTSVPSSIIYENNEDKSLFKVLFTIPPNDIFYNADFNFGNNDTNNDIQLRLDLIQPEIWVLNKYNFPPCEDFLANTNSPTTTKTTPSTFTSTMDYNYVLSCASYGAYTSSSNPEDMESPTPGVNVQNYQPYIIPYLNSLEASGEFVTDDISFNLTTGDPIEFKNMTFLDVNDSNALVGGLGLAGTPKGSGFLYSLVDQGIIESPGYSLWFSNDSNPDTAIAQLLPGVINQKYYVGNFYQFDMIPHTGFRYNASYQEQNQDLFNLILPVIQISDILMVNLNSGQKLTMKSNDDQIPVLLDSRASNFYLPLEVIINLAIQTRAYYSSELTRWLVTCHPLLDVKAAIEIQIGGLTVSVPISKFIGRAVYNGSSLNFENGAEACVLKVVPSSVTGYNMLGLPFLKQIYLAVDNEGKKIALANSNKYLKMTKQDIFNDVANPDQHVYNNTAGELADITNSNSSSSDTTSSIESGNSGISGNSIDYIKSGKIPFATVYSESTEGTFIYSSLSQTSGATVILDIPARFSGASIKSGLIYLNGDSSTSVTTSAINSTSTSKAQANLNGQMNYVEVGTMKFPTAILSLVLSIFLIIITLL
Protein: Aldehyde dehydrogenase family 16 member A1 (Q8IZ83)
Organism: Homo sapiens (Human)
Interaction partners:
- Deoxyribose-phosphate aldolase
- Maspardin
- Glutathione S-transferase LANCL1
- Bifunctional epoxide hydrolase 2
- Protein-L-isoaspartate
- Delta-1-pyrroline-5-carboxylate synthase
- Toll-like receptor 1
- Endoplasmic reticulum resident protein 29
Sequence:
MAATRAGPRAREIFTSLEYGPVPESHACALAWLDTQDRCLGHYVNGKWLKPEHRNSVPCQDPITGENLASCLQAQAEDVAAAVEAARMAFKGWSAHPGVVRAQHLTRLAEVIQKHQRLLWTLESLVTGRAVREVRDGDVQLAQQLLHYHAIQASTQEEALAGWEPMGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLLAQLAGELGPFPGILNVLSGPASLVPILASQPGIRKVAFCGAPEEGRALRRSLAGECAELGLALGTESLLLLTDTADVDSAVEGVVDAAWSDRGPGGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAVDMGARGAAACDLVQRFVREAQSQGAQVFQAGDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYLRPSGTPARLSCLSKNLNYDTFGLAVPSTLPAGPEIGPSPAPPYGLFVGGRFQAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQGAELKAAEAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATVFPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRGCPRAWDQEAEGAGPELGLRVARTKALWLPMGD
Protein: Guided entry of tail-anchored proteins factor 1 (Tail-anchored protein insertion receptor WRB) (Tryptophan-rich basic protein) (Q8K0D7)
Organism: Mus musculus (Mouse)
Function: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with CAMLG/GET2, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required to ensure correct topology and ER insertion of CAMLG.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O00258}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- ATPase GET3
- Guided entry of tail-anchored proteins factor CAMLG
- SH3 domain-binding glutamic acid-rich protein
- Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Sequence:
MSASETDRWAWLLVLSFVFGCNLLRILLPSLSSFISRVLQKDAEQESQMRAEIQGMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWFISVAFYILQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGIGITCWILVCNKVVAIVLHPFS
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q9VKB1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MASKVHPSPGAARSVWALPLTASSSCNMVVAEEDGHAHADDIHLDHRPHSPPLTGRGTDGGHGSSGVEDHENVLLFEGLDGATTVSLDDIFDIIKNGEVSEVENLVDKFGMECLSARDRHGYTPAHWIALNGNVQLMRYLIERTAPIDLPCLGTQGPRPIHWACRKGHASVVQVLLQAGVAVNAADFKGLTPLHLACMYGRTATAAYLLGMGALNNLTDINGDTALHWAAYKGHADLMRLLMYSGVELQKTDNFGSTPLHLACLSGNMTCVRLLCEKSQLDLEPRDKNGKTPIMLAQAHQHQDVVRLLYGEVKKKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWNILRRSHYCFIYWNAVMWISWAIANRRDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEGFTMLYVLGLIEAVVFCGLGWILTCTSILHACMNLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNLLEFFVCLPDRGDDNDLLLEDNI
Protein: Acyl-lipid (7-3)-desaturase (EC 1.14.19.31) (Acyl-lipid 4-desaturase) (Delta-4 fatty acid desaturase) (Q6VPV2)
Organism: Diacronema lutheri (Unicellular marine alga) (Monochrysis lutheri)
Function: Fatty acid desaturase that introduces a cis double bond at the 4-position in 22-carbon polyunsaturated fatty acids that contain a Delta(7) double bond, resulting in the production of delta-4 desaturated fatty acid docosahexanoic acid (DHA). Mediates desaturation of 22:5n-3 and 22:4n-6 into 22:6n-3 and 22:5n-6 respectively.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MPPSAASEGGVAELRAAEVASYTRKAVDERPDLTIVGDAVYDAKAFRDEHPGGAHFVSLFGGRDATEAFMEYHRRAWPKARMSKFFVGSLDASEKPTQADSAYLRLCAEVNALLPKGSGGFAPPSYWLKAAALVVAAVSIEGYMLLRGKTLLLSVFLGLVFAWIGLNIQHDANHGALSRHSVINYCLGYAQDWIGGNMVLWLQEHVVMHHLHTNDVDADPDQKAHGVLRLKPTDGWMPWHALQQLYILPGEAMYAFKLLFLDALELLAWRWEGEKISPLARALFAPAVACKLGFWARFVALPLWLQPTVHTALCICATVCTGSFYLAFFFFISHNFDGVGSVGPKGSLPRSATFVQRQVETSSNVGGYWLGVLNGGLNFQIEHHLFPRLHHSYYAQIAPVVRTHIEKLGFKYRHFPTVGSNLSSMLQHMGKMGTRPGAEKGGKAE
Protein: Nuclear envelope integral membrane protein (Q9VXD6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Contributes to nuclear envelope stiffness in germ cells. Required for male and female fertility.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:32923640}; Multi-pass membrane protein {ECO:0000255}; Nucleoplasmic side {ECO:0000250|UniProtKB:B9X187}.
Interaction partners:
Sequence:
MHSAGLLMLTVAGYFTSGIPGNTASSDVAYLTPGTYINLSENILGLQTLRTFCYPGKRLTVSSLFETVEFVLAIGSDDYSQYGGKTPEEVLQHYKDKQSLFSITLFAQKRQLLQLSPFEQQCIGISSRQAYTVILNSIPLDLWRLAQFAVGILILFSARRLAKNSVFYYLVGIVIGICASLLVVIYLAAKLFPRRTMMYGVLIGGWTIGFYVIKQLADNLRLILITYRDHVLGYLVITGLISFLICYRIGPPKNPRSQTIVMWVLQAIGAVMAYFSSWHTSAVIFIMVLVFVAHYFPISWTNQIKFMYRRRFPLKRRMLTQEEYEQQTAVETSKSLADLRKYVNSPECKQWAVMGKLRDPLRFASFANGAPHLDDEEIEDHSRTIEESMDAAPEEESVEEPEEDKPAELLPLPNSQFRYQQAARNSEPEPESESDDSEEEEFFEQEVDLRQVVQ
Protein: Protein IQ-DOMAIN 21 (AtIQD21) (Protein GROWTH CONTROLLED BY ABSCISIC ACID 2) (Protein GUARD CELL ASSOCIATED 2) (Q9ASW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity). Involved in abscisic acid (ABA)-mediated signaling pathways leading to the production of hydrogen peroxide H(2)O(2) and the subsequent [Ca(2+)] cytoplasmic oscillations-dependent regulation of stomatal closure. Required for [CO(2)] modulation of the cytosolic Ca(2+) transient rate and for high CO(2)-induced stomatal closing. Essential for both cold and ABA induction of XERO2. May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:28115582}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:28115582}. Cell membrane {ECO:0000269|PubMed:28115582}.
Interaction partners:
Sequence:
MGKKGSGGWFSTVKKKVFKSSPKDSKRENNIGSNNADIWQQQHDTQEVVSFEHFPAESSPEISHDVESTASTPATNVGDRKHAMAVAIATAAAAEAAVAAAQAAAKVVRLAGYNRQTEEDSAAVLIQSHYRGYLARRALRALKGLVRLQALVRGNHVRKQAQMTMKCMQALVRVQGRVRARRLQVAHDRFKKQFEEEEKRSGMEKPNKGFANLKTEREKPKKLHEVNRTSLYQTQGKEKERSEGMMKRERALAYAYTYQRQMQHTNSEEGIGLSSNGPDRNQWAWNWLDHWMSSQPYTGRQTGPGPGPGQYNPPPYPPFPTAAATTTSDDVSEKTVEMDVTTPTSLKGNIIGLIDREYIDLGSYRQGHKQRKSPTHIPSYMAPTASAKAKVRDQGPTVKLQGTSFMPYWNSSTKNGSVNGSGCDSSSSGGAITTGYPGPRSPNPKSDIRRKPVSPSQSPTGFGKRGWRHDH
Protein: Odorant receptor 82a (P82986)
Organism: Drosophila melanogaster (Fruit fly)
Function: Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Odorant receptor 7a
- Odorant receptor 35a
- Odorant receptor 74a
- Odorant receptor 65a
- Odorant receptor 56a
- Odorant receptor 85a
- Odorant receptor 67b
- Odorant receptor 33a
- Odorant receptor 30a
- Odorant receptor 47a
Sequence:
MGRLFQLQEYCLRAMGHKDDMDSTDSTALSLKHISSLIFVISAQYPLISYVAYNRNDMEKVTACLSVVFTNMLTVIKISTFLANRKDFWEMIHRFRKMHEQSASHIPRYREGLDYVAEANKLASFLGRAYCVSCGLTGLYFMLGPIVKIGVCRWHGTTCDKELPMPMKFPFNDLESPGYEVCFLYTVLVTVVVVAYASAVDGLFISFAINLRAHFQTLQRQIENWEFPSSEPDTQIRLKSIVEYHVLLLSLSRKLRSIYTPTVMGQFVITSLQVGVIIYQLVTNMDSVMDLLLYASFFGSIMLQLFIYCYGGEIIKAESLQVDTAVRLSNWHLASPKTRTSLSLIILQSQKEVLIRAGFFVASLANFVGICRTALSLITLIKSIE
Protein: Small ribosomal subunit protein eS7 (40S ribosomal protein S7) (P62081)
Organism: Homo sapiens (Human)
Function: Required for rRNA maturation.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:20873783}. Cytoplasm {ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:9687515}. Nucleus, nucleolus {ECO:0000269|PubMed:34516797, ECO:0000269|PubMed:9687515}. Note=Although RPS7 is functional within the cytoplasm, the assembly of ribosomal subunits occurs in the nucleus. RPS7 nuclear import is mediated by IPO5/RanBP5, IPO7/RanBP7, KPNB1/importin-beta or TPNO1/Trn (PubMed:9687515). Colocalizes with NEK6 in the centrosome (PubMed:20873783). {ECO:0000269|PubMed:20873783, ECO:0000269|PubMed:9687515}.
Interaction partners:
- Small ribosomal subunit protein eS8
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein eL43
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein uL24
- Ubiquitin-ribosomal protein eL40 fusion protein
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein uL1
Sequence:
MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL
Protein: 1,3-beta-glucan synthase component bgs2 (EC 2.4.1.34) (1,3-beta-D-glucan-UDP glucosyltransferase) (Meiotic expression up-regulated protein 21) (O13967)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Alternate catalytic subunit of the 1,3-beta-glucan synthase (GS) complex (By similarity). Synthesizes 1,3-beta-glucan, a major structural component of the yeast cell wall (By similarity). Has a role in ascospore development where it is required for the assembly of a functional spore wall.
Subcellular location: Prospore membrane {ECO:0000269|PubMed:10922478, ECO:0000269|PubMed:11069657}; Multi-pass membrane protein {ECO:0000269|PubMed:10922478, ECO:0000269|PubMed:11069657}.
Interaction partners:
- Probable UTP--glucose-1-phosphate uridylyltransferase
- Probable UTP--glucose-1-phosphate uridylyltransferase
- Glucan 1,3-beta-glucosidase 2
- Glucan 1,3-beta-glucosidase 1
- Glucan 1,3-beta-glucosidase
- Serine palmitoyltransferase 1
- 1,3-beta-glucan synthase component bgs3
- Chitin synthase regulatory factor 4
- 1,3-beta-glucanosyltransferase gas1
- 1,3-beta-glucan synthase component bgs1
Sequence:
MSWHEQDYGFGTSSENSKINSDEFEDSMDVTEFNNPGEESTYPQANSWNDSNKTKDIAEYYDYSWSGQREANQQIPQPVPVQPRYPDEQNFSMNGETYPSEAYDYDYSGQEEAINAMNILQGNLERSNEYYSEGVPYSEEDLGAYAGGMTEDDQMYSNFNETGEFNLDIGSSKFSYLNAKNPYPAWIAENSIPITAENILEIFQELQAKFGFQYDSMLNMYDFFMVLLDSRSSRMDAENALKSLHADYIGGRNANYRKWYFSSSMDIDDSVGLQNCKFSSNGPKIKQAKKKQKRKSNKAETEGTNEPETSVQIDPLNVSMENWENEMKNLDCETQVRQLALYLLCWGEANNIRFCPECLCFIFKLANDFMQSEDYAKSEPIEDDCFYLDNVITPLYEFIRDQQFELLDGKLVRRERDHAQIIGYDDINQLFWYPEGIARIVTVDGTQLITLPKWERFHKLSEVDWKKAFYKTFYESRSWFHLVTNFNRIWVIHFTTYWYYTVFNSPTIIEKNFRQSVGPKPIPSCHWTSVSLGGAVATLLMLLATIFEWIHVPRKFPGSRPLLKRFLILILFFILNVAPTVFVFGFSTEEQQRTTGRLTVAIVHFIFSVFTFIYFSLVPLNNLFHRAYKSSSRTHLANRYFTADYARLQINDMCVSWGLWLLVFGAKFTESYFFLSLSFRDPILVLSTMKPYLCNITFLGSHLCIWQPKILLGIMYVTDLVLFFLDTYLWYILVNTVFSVARSFFLGISIWTPWRNIFARMPKRIYSKILCTPEVDSSYKPKVLVSQIWNSIIISLYREHLLAIEHVQRLIYHQVNSLDGDGSKTLKTPTFFVSQEDSSFNTEYFPAHSEAERRLSFFAQSLATPIPEPIPVDAMPTFTVLVPHYGEKILLSLKEIIREQDKLSRVTLLEYLKQLHANEWKCFVRDTKILAEEDALSNQDLNSQDESMKAEQLHKKFDDLPFYCIGFKNATPEYTLRTRIWASLRSQTLYRTVSGFMNYSRAIKLLYRVENPDVAQLFEGQMDVLEYELDRMASRKFKMCVSMQRYAKFTADEIENTEFILRAYPDLLIAYLDEDPPKEGETTPQLYAALIDGYSELDENKKRKPKYRIKLSGNPILGDGKSDNQNLSLPFYRGEYIQLIDANQDNYLEECLKIRSILAEFEAFDLKTNDPYAETNALYQNNPVAIMGAREYIFSENIGILGDVAAGKEQTFGTLFARTMAQIGGKLHYGHPDFLNAIYMTTRGGVSKAQKGLHVNEDIYAGMTALQRGGRIKHCEYYQCGKGRDLGFGSILNFTTKIGTGMGEQMVSREYYYLGTQLPFDRFLSFYYAHPGFHINNIFIMLSVQLFMVVLVNLGGMYHVVTVCDYDHDQKLTVPMRPEGCYQLNPVVNWLKRCIISIFIVFFISFVPLTVQELTERGAWRALTRLGKHFASFSPMFEVFACQTYAQSVIANLSFGGARYIGTGRGFATARLSFSLLFSRFAGPSIYLGSRTLLMLLFGTMTVWIPHLIYFWISTLAMCISPFIFNPHQFSWTDFFVDYREFIRWLSRGNSRSHINSWIGYCRLTRTRITGYKRRLLGVPVSKGVIDTSRAHFTNMFFTEIFIPLMLVPLTLVSYFFIDSQPGNPDPSKVTNPILRILILAFLPIIVAAVVSMTFAGMACMMGPLLDLCCKKFGAVLAALAHGITVFMFIIVFEVSWYLEAWCLAKTVLSMLCIIAIQRFFFKIIQVLFLTRELKHDGTNLAWWTGKWYSRGLGFHALSQPSRELICKMTELNFFAADFFLCHLLLFLMLPVLLIPFIDRWHSMMLFWLKPSKQIRPPIYSMRQNRLRKKIVQRYGTMFFLLLIAFLALIIIPLVVAKDLLANFEMDILRTYGLMQPRDTNWTENGTNWTTVNE
Protein: Ribosome-inactivating protein PD-L3/PD-L4 (EC 3.2.2.22) (rRNA N-glycosidase PD-L3/PD-L4) (P84854)
Organism: Phytolacca dioica (Bella sombra tree) (Phytolacca arborea)
Function: Inhibits protein synthesis. Does not cleave supercoiled pBR322 dsDNA.
Interaction partners:
Sequence:
VNTITFDVGNATINKYATFMESLRNEAKDPTLKCYGIPMLPDSNLTPKYVLVKLQDASSKTITLMLRRNNLYVMGYSDLYNGKCRYHIFNDISSTESTDVENTLCPNSNSREKKAINYNSQYSTLQNKAGVSSRSQVQLGIQILNSDIGKISGVSTFTDKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPKVLSLEENWGKISLAIHNAKNGALTSPLELKNADDTKWIVLRVDEIKPDMGLLNYVSGTCQTT
Protein: Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) (V9HWC3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL
Protein: Mitochondrial Rho GTPase 1 (MIRO-1) (EC 3.6.5.-) (Ras homolog gene family member T1) (Q8BG51)
Organism: Mus musculus (Mouse)
Function: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Promotes mitochondrial fission during high calcium conditions (By similarity).
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8IXI2}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q8IXI2}. Note=Colocalizes with MGARP and RHOT2 at the mitochondria. {ECO:0000250|UniProtKB:Q8IXI2}.
Interaction partners:
- Trafficking kinesin-binding protein 1
- Trafficking protein, kinesin binding 2
- Kinesin heavy chain isoform 5A
- Mitofusin-2
- Kinesin-1 heavy chain
- Unconventional myosin-XIX
- Mitofusin-1
- E3 ubiquitin-protein ligase parkin
- Serine/threonine-protein kinase PINK1, mitochondrial
- Armadillo repeat-containing X-linked protein 1
Sequence:
MRAGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAETICDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR
Protein: Protein Dok-7 (Downstream of tyrosine kinase 7) (Q18PE1)
Organism: Homo sapiens (Human)
Function: Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Synapse {ECO:0000250}. Note=Accumulates at neuromuscular junctions. {ECO:0000250}.
Interaction partners:
- Muscle, skeletal receptor tyrosine-protein kinase
- Agrin
- 43 kDa receptor-associated protein of the synapse
- Acetylcholinesterase collagenic tail peptide
- Acetylcholinesterase
- Acetylcholine receptor subunit epsilon
- Cholinesterase
- Acetylcholine receptor subunit beta
- Sodium channel protein type 4 subunit alpha
- Acetylcholine receptor subunit delta
Sequence:
MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSLTLEDICGLEPGLPYEGLVHTLAIVCLSQAIMLGFDSHEAMCAWDARIRYALGEVHRFHVTVAPGTKLESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGGTRCGYWAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGPHAGPPPAFFSACPVCGGLKVNPPP
Protein: Reproductive homeobox 3A (Reproductive homeobox 3E) (Reproductive homeobox on X chromosome 3) (Q4TU90)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Reproductive homeobox 12
Sequence:
MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEEGKNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL
Protein: Capping actin protein, gelsolin like (E7ENU9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYK
Protein: Dienelactone hydrolase family protein (AFU_orthologue AFUA_6G01940) (C8VA57)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MSGVSKACCSIPPIVAKGYQPKGEYKTINGLKTYVTGPSDATKAILVVYDIFGFFPQTLQGADILATSSKQKYRIFMPDFFEGEPADITWFPPSNEDQKNKLGNFFQTKAAPPKTLSKIPGVVSEANSYAPSGGAFESWSILGYCWGGKITVLSSGSENKTFKAAVQCHPAMLDPNDAKGVNIPMALLASKDEKPDDVSQFGANLKVDHYVETFPTQIHGWMAARSQLEDEQVRKEYERGYQTALDFLAKHA
Protein: Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4) (Q6P6G4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSKHRLIILRHGEGQWNKENRFCSWVDQKLNSDGLEEARNCGRQLKALNFEFDLVFTSILNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPFFHEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWKERISPEILKGKTVLISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAIRPHQFLGNQEAIQAAIKKVDDQGKVRQNK
Protein: Nascent polypeptide-associated complex subunit beta (Q383V9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nascent polypeptide associated complex subunit, putative
- 60S ribosomal subunit protein L31, putative
- 60S ribosomal protein L35, putative
- 60S ribosomal protein L10, putative
- Nuclear pore protein
- 60S ribosomal protein L6, putative
- 60S ribosomal protein L17, putative
- Nuclear pore complex protein
- 60S ribosomal protein L4
- 60S ribosomal protein L37a, putative
Sequence:
MPSITQETLRRRAEFVRTGGRGSVRRTVKVAHRNTGDDKKVQQVLKRLNVSPFNDVDDAVLYRHDGTAYYFEKPKVQASMQSQCFVVSGAYDVKEASEVPS
Protein: Nitrate transporter 2.1 (Nitrate assimilation related protein 3) (Q39608)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Involved in nitrate transport, but does not seem to be able to mediate transport by its own. Acts as a dual component transporter with NAR2 (system 1). Imports nitrate with high affinity when expressed with NAR2 in a heterologous system (Xenopus oocytes). Involved in a high affinity and a high capacity transport specific for both nitrate and nitrite.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAEKPATVNAELVKEMDAAPKKYPYSLDSEGKANYCPVWRFTQPHMMAFHLSWICFFMSFVATFAPASLAPIIRDDLFLTKSQLGNAGVAAVCGAIAARIFMGIVVDSIGPRYGAAATMLMTAPAVFCMALVTDFSTFACVRFFIGLSLCMFVCCQFWCGTMFNVKIVGTANAIAAGWGNMGGGACHFIMPLIYQGIKDGGVPGYQAWRWAFFVPGGIYILTATLTLLLGIDHPSGKDYRDLKKEGTLKAKGAMWPVVKCGLGNYRSWILALTYGYSFGVELTVDNVIVEYLFDQFGLNLAVAGALGAIFGLMNLFTRATGGMISDLVAKPFGMRGRIWALWIIQTLGGIFCIVLGKVSNSLSSTIVIMIVFSIFCQQACGLHFGITPFVSRRAYGVVSGLVGAGGNTGAAITQAIWFAGTAPWQLTLSKADGFVYMGIMTIGLTLPLFFIWFPMWGSMLTGPREGAEEEDYYMREWSAEEVASGLHQGSMRFAMESKSQRGTRDKRAAGPARVPQQLRLGARCCQARGGLIRCVLAQSLGATGCSD
Protein: Cysteine synthase 1 (EC 2.5.1.47) (At.OAS.5-8) (Beta-substituted Ala synthase 1;1) (ARAth-Bsas1;1) (CSase A) (AtCS-A) (Cys-3A) (O-acetylserine (thiol)-lyase 1) (OAS-TL A) (O-acetylserine sulfhydrylase) (Protein ONSET OF LEAF DEATH 3) (P47998)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a major cysteine synthase, probably involved in maintaining organic sulfur level.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Assimilatory sulfite reductase
- Probable cystathionine gamma-synthase 2
- Cystathionine gamma-synthase 1, chloroplastic
- Serine acetyltransferase 1, chloroplastic
- L-cysteine desulfhydrase
- Probable L-cysteine desulfhydrase, chloroplastic
- Cystathionine beta-lyase, chloroplastic
- Serine acetyltransferase 3, mitochondrial
- Serine acetyltransferase 5
- Methionine gamma-lyase
Sequence:
MASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLFDATRKEAEAMTFEA
Protein: Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2) (O95834)
Organism: Homo sapiens (Human)
Function: Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11694528}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11694528}. Note=Colocalizes with the microtubule cytoskeleton. Colocalizes with the mitotic spindle. {ECO:0000269|PubMed:11694528}.
Interaction partners:
- Tubulin beta-2A chain
- Tubulin beta-2B chain
Sequence:
MSSFGAGKTKEVIFSVEDGSVKMFLRGRPVPMMIPDELAPTYSLDTRSELPSCRLKLEWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAIHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHMLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHIYFWTLEGGSLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGHGDTLYVGTTRNSILQGSVHTGFSLLVQGHVEELWGLATHPSRAQFVTCGQDKLVHLWSSDSHQPLWSRIIEDPARSAGFHPSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDPATCKQITSADAVRNMEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q8IGZ0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSFTKWFKKKGGDGGSISEIGAPTNFQRHFHVSRNQETGDLEGLPAPWLRLMNSQITRDEQDKNPDAAYHAVKYYNYSIKKKENEVFKPFITGDVIHEESKEIENYVNYKNKHKSQDPEKSDDDGSSTATETESSSGCGSSAGNSNSSSINDSSQQSTVPLDALEEVFKELKTNLEHRETLKAAPQEPPPVPPKKSPHTIPPKPQIKPKPRVTQKFSRTSDIRRDEDSDNQHKINTDTIIIKPAVGAQDAGADDNPDETILRRSKEKRAQKTDAEIYVELRVICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPDLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKVLRRNV