wanglab/gogpt-training-data huggingface dataset:
Protein: Glycosyltransferase (Q7Y217)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Glycosyltransferase-pyrophosphoryl-undecaprenol N-acetylglucosamine transferase)
- Uncharacterized protein At5g48340
- DCD
- DNA-binding protein
- dolichyl-phosphate beta-glucosyltransferase
- Dolichol-phosphate mannosyltransferase subunit 1
- Uncharacterized protein At4g19900
- Glycosyltransferase
- F-box/kelch-repeat protein At1g64840
- At3g57630
Sequence:
MVKASTMQRKRWALMVLLFLSVSTVCMILVRSSFETCSISSQFVEEKNGESSAAKFQSNPLDFMKSKLVLLVSHELSLSGGPLLLMELAFLLRGVGADVVWITNQKPLEDDEVVYSLEHKMLDRGVQVISAKGQKAVDTSLKADLIVLNTAVAGKWLDAVLKENVVKVLPKILWWIHEMRGHYFNADLVKHLPFVAGAMIDSHATAGYWKNRTQARLGIKMPKTYVVHLGNSKELMEVAEDSVAKRVLREHVRESLGVRNEDLLFGIINSVSRGKGQDLFLRAFHESLERIKEKKLQVPTMHAVVVGSDMSKQTKFETELRNFVREKKLENFVHFVNKTLTVAPYIAAIDVLVQNSQARGECFGRITIEAMAFKLPVLGTAAGGTMEIVVNGTTGLLHSAGKEGVIPLAKNIVKLATQVELRLRMGKNGYERVKEMFLEHHMSHRIASVLKEVLQHAKARALR
Protein: Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic) (Q9QXU8)
Organism: Rattus norvegicus (Rat)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores (By similarity).
Subcellular location: Cytoplasm {ECO:0000305}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:Q9Y6G9}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q9Y6G9}. Recycling endosome membrane {ECO:0000250|UniProtKB:Q9Y6G9}.
Interaction partners:
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic dynein 1 heavy chain 1
- Dynactin subunit 1
- BICD cargo adaptor 2)
- Cytoplasmic dynein 1 light intermediate chain 2
- Cytoplasmic dynein 1 intermediate chain 2
- Dynein light chain roadblock-type 1
- Dynein light chain Tctex-type 1
- Dynein light chain Tctex-type 3
- Dynein light chain 2, cytoplasmic
Sequence:
MAAVGRVGSFGSSPPGLASTYASGPLANELASGSGGPAAGDDEDGQNLWSRILREVSTRSRSKLPTGKNVLLLGEDGAGKTSLIRRIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYHKGLLKFSLDALSLRDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKEMEQKLIRDFQEYVEPGEDFPASPQRRATAAQEDRDDSVVLPLGADTLTHNLGLPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKIEDNFEDIITKPPVRKFVHEKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGSPRTPNRSVSSNVASVSPIPAGSKKIDPNMKAGATSEGVLANFFNSLLSKKTGSPGGPGVGGSPGGGAAGASTSLPPSAKKSGQKPVLSDVHAELDRITRKPASVSPTTPPSPTEGEAS
Protein: HSP20-like chaperone domain-containing protein (Q54QE9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MASNLLVPQDIRLPSILGYILSGKELEVILKKNQEESAKVYKRNKNLENDIKNHRVKEEEYLKIIEQLEKHNNELSKKLNCYIGKTTIPENGIKEYDIIIDIPAVDYFSQKETAWLIFLSQKLKEKMNGPNGFNPLEPFNSLFAEFKKYSTLACLGCFNIGKTFFINKYNNSYLPSGTQSQTIGLSLSICHNNETITIDTAGSNTSLKVGENRSEEQLARKESTEMFIRDMSFSLANTIVYVLNELTWTDQRFILALQSKIQSLRTEQKINKTLIIVHNYPKINSMEELLVEIKTYMDHPFNGTFHHQIDFKTIKSKDEVVLFFTESVNNSYHFFLCNDNSEFGKKYNDLTIEKIRSTNKEYNDKLDFDKVLLSGLQNNMVSYCKSPSKLKISEFTKDDKIIENCNKENGKILFDKESGEFSVHLKELTEIYEKVTPHKTTISQIPVFKIYPENDSNRENEFKLIDNKVEFIGLQMVFWNGFRPNYDIVKVGSDLRYLIEVPQMVLDEIFHETKYENTKWNLIVKGVKKLQFDMKNSESGYPSEETSLYLSNNQRRDGSFELILNIPNNYHPKNPEVVLEKGVLCFTFKLIE
Protein: Rhodopsin (P15409)
Organism: Mus musculus (Mouse)
Function: Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling.
Subcellular location: Membrane {ECO:0000250|UniProtKB:P02699}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P02699}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:15961391, ECO:0000269|PubMed:27353443, ECO:0000269|PubMed:28151698}. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia. {ECO:0000250|UniProtKB:P08100}.
Interaction partners:
- S-arrestin
- Rhodopsin kinase GRK1
- Guanine nucleotide-binding protein G
- Recoverin
- Guanine nucleotide-binding protein G
- Arrestin-C
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- G protein-coupled receptor kinase 4
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Sequence:
MNGTEGPNFYVPFSNVTGVVRSPFEQPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVVFTWIMALACAAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASATASKTETSQVAPA
Protein: Centromere protein N (CENP-N) (Interphase centromere complex protein 32) (Q96H22)
Organism: Homo sapiens (Human)
Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
Subcellular location: Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres. Kinetochore-bound levels decrease when cells enter mitosis and increase again when cells exit mitosis.
Interaction partners:
- Centromere protein T
- Centromere protein Q
- Centromere protein H
- Centromere protein L
- Centromere protein C
- Centromere protein I
- Centromere protein U
- Centromere protein M
- Histone H3-like centromeric protein A
- Centromere protein O
Sequence:
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRDK
Protein: Transmembrane protein 18 (Q3TUD9)
Organism: Mus musculus (Mouse)
Function: Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q96B42}. Nucleus membrane {ECO:0000250|UniProtKB:Q96B42}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- BTB/POZ domain-containing protein KCTD15
Sequence:
MSSAYSVRSFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLCLVVLVYSAEYINEVAAVNWRLFSKYQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQEERKERRRRRKEE
Protein: Transmembrane protein 121 (Q9BTD3)
Organism: Homo sapiens (Human)
Function: May play a role in MAPK signaling.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=May localize to the plasma membrane. {ECO:0000269|PubMed:15950185}.
Interaction partners:
Sequence:
MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQASLWEPPRSGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALSLELQPPPPQRNSVPPPPPPLHGPPGRPHMSSPTRDPLDT
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2) (O97725)
Organism: Bos taurus (Bovine)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:18721790}; Peripheral membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 4
- NADH dehydrogenase flavoprotein 3, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 1
- Cytochrome c oxidase subunit 5A, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 5
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase 1 beta subcomplex subunit 6
Sequence:
MELLQVLKRGLQQVSGHGGLRGYLRVLFRANDVRVGTLVGEDKYGNKYYEDNKQFFGRHRWVIYTTEMNGKNTFWDVDGSMVPPEWHRWLHCMTDDPPTVKPPTARKFIWTNHKFNLSGTPQQYVPYSTTRKKIQEWVPPSTPYK
Protein: D-alanyl-D-alanine endopeptidase (DD-endopeptidase) (EC 3.4.21.-) (Penicillin-binding protein 5) (PBP-5) (P72161)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Cell wall formation.
Subcellular location: Periplasm {ECO:0000305}.
Interaction partners:
- Peptidoglycan D,D-transpeptidase FtsI
- Peptidoglycan D,D-transpeptidase MrdA
- Penicillin-binding protein 1B
- Penicillin-binding protein 1A
- DNA translocase FtsK
- Endolytic murein transglycosylase
- Peptidoglycan glycosyltransferase MrdB
- 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
Sequence:
MRNRLLSLVTLFLSLSVATAVSASPPPKAGLPLQQELASGSALVTDQNTGKVLYSRNPDLVVPIASITKLMTAMVVLDSKLPLDEVLPIAISETSEMRGVFSRVRVGSQISRRDMLLLALMSSENRAAASLAQNYPGGKNAFVKAMNAKAHALGMKNTRYVEPTGLSLHNVSTARDLTRLLVASRQYPLLSQWSTTPEKTVAFRHPNYTLGFRNTNHLINNKTWNIQLTKTGFTNEAGHCLVMRTTINRSPVNLVVLDAFGKYTHFADATRLRRWLETGQVTAIPAAAKAYRLQRDRERGLGQPVAQAVR
Protein: GA-binding protein subunit beta-2 (GABP subunit beta-2) (GABPB-2) (Q8TAK5)
Organism: Homo sapiens (Human)
Function: May function as transcription factor capable of interacting with purine rich repeats (GA repeats).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- GA-binding protein alpha chain
Sequence:
MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSMAAPFIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLSNSHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFIVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEGELEERETKVTGSAGTTEPHTRVSMATVSS
Protein: Guanine nucleotide-binding protein alpha-3 subunit (P28052)
Organism: Caenorhabditis elegans
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Promotes transcription of 3',5'-cyclic phosphodiesterases pde-1 and pde-5, leading to reduced cGMP levels in sensory neurons. This causes suppression of insulin production and signaling which leads to increased daf-16 activity and contributes to increased adult lifespan and resistance to oxidative stress. In addition, by reducing cGMP levels, inhibits TGF-beta signaling pathways. Involved in behavioral response to P.aeruginosa by controlling the expression of daf-7, a member of the TGF-beta family, in ASJ sensory neurons. Plays a role in the avoidance response to the noxious chemical quinine in ASH sensory neurons.
Interaction partners:
- Receptor-type guanylate cyclase daf-11
- Cyclic nucleotide-binding domain-containing protein
- Guanine nucleotide-binding protein subunit alpha
- Cyclic nucleotide-gated channel
- Receptor-type guanylate cyclase gcy-10
- Guanine nucleotide-binding protein subunit beta-1
- Guanine nucleotide-binding protein subunit beta-2
- SRBC-64)
- Serpentine Receptor, class BC
- G-protein coupled receptor daf-37
Sequence:
MGLCQSAEDKELTLKSKAIDKEMMQNHMSQQKVVKLLLLGAGECGKSTVLKQMRILHDHGFTAEEAEQQKSVVFNNTLQAMTAILKGMEALRMTFDKPIRENDAKFVMESHKMLQEAKVFPEELANAIQALWNDKAVQQVIAKGNEFQMPESAPHFLSSLDRIKLPDYNPTEQDILLSRIKTTGIVEVKFQMKSVDFRVFDVGGQRSERKKWIHCFEDVNAIIFIAAISEYDQVLFEDETTNRMIESMRLFESICNSRWFINTSMILFLNKKDLFAEKIKRTSIKSAFPDYKGAQTYDESCRYIEEKFDGLNANPEKTIYMHQTCATDTDQVQMILDSVIDMIIQANLQGCGL
Protein: Protein kinase C-like 2 (PKC2) (EC 2.7.11.13) (P90980)
Organism: Caenorhabditis elegans
Function: PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Interaction partners:
- Acetylcholine regulator unc-18
- G protein-coupled receptor kinase 2
- Syntaxin-binding protein 1
- Probable syndecan
- Rab-3-interacting molecule unc-10
- Transient receptor potential cation channel subfamily A member 1 homolog
Sequence:
MSLSTNSSVKEDEAQRIEGKAFVRRGALRQKNVHEIKSHKFIARFFKQPTFCSHCKDFLWGITKQGFQCQVCTLVVHKRCHEFVNFACPGADKGVDTDDPRQQHKWKVQTYSSPTFCDHCGSLLYGILHQGMKCQSCDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAASGWYKLLSAEEGEFYNINITPEYDEDMEKVRKKMNENFITRDNSSSKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENFDHSFLKLPTKMTPPDWEVLENLKGDEFSNFSFVNPFYVKDVEP
Protein: High mobility group protein DSP1 (Protein dorsal switch 1) (Q24537)
Organism: Drosophila melanogaster (Fruit fly)
Function: Binds preferentially single-stranded DNA and unwinds double-stranded DNA.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Beclin-1-like protein
- Transcription factor Jra
- Signal transducer and transcription activator
- Histone deacetylase HDAC1
- Transcription factor kayak, isoforms A/B/F
- Brahma associated protein 111kD
Sequence:
MEHFHQIQQTIQHYQQQLAAQQQQQVQQQQLQQHQVVVQQNQQQAHQNSSNTTAGVGTQQLFTYKMASSFPNPATTMAQVVATSNAAGTTGYDYRLNMAQAAAAAAVPGSQWWYSAANQGQVDANTAAQLQHQQQQQQQQQQQQQQQHQQQQQMQQQQQQQNVINSASPMSRVKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQHQQLEEQHDDDDGDGDDDENQ
Protein: G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (P70507)
Organism: Rattus norvegicus (Rat)
Function: Specifically phosphorylates the activated forms of G protein-coupled receptors. Plays an important role in the regulation of renal sodium handling and blood pressure.
Subcellular location: Cytoplasm. Cytoplasm, cell cortex {ECO:0000250}.
Interaction partners:
- ARF GTPase-activating protein GIT1
- Beta-arrestin-2
- Beta-arrestin-1
- Rhodopsin
- Mu-type opioid receptor
- ARF GTPase-activating protein GIT2
- C-X-C chemokine receptor type 4
- NADH-ubiquinone oxidoreductase chain 1
- C-C motif chemokine receptor 7
- TNF receptor-associated factor
Sequence:
MELENFMANTLLLKARQGFTKKTGRSKKWRELLKLPPVSMCSDLRHSIEKDFSSLCDQQPIGRLLFRQFCNTKPDLKRCIEFLDAAAEYEVTIEEEQREFGLSIYSRFFKENSEVSLPQIPPDLVKECKCNLKQSSPSQNVFQDCAGVIYKYLSEKPFEEYQESTYYNRFLQWKWLERRPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGNPGFEEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDHGHIRISDLGLALEIPEGEMVRGRVGTVGYMAPEIISHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREEMERRVKTETEEYSERFSENAKSICSMLLTKDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPPFCPDPEAIYCKDILDIGQFSVVKGVNLDTNDEIFYTQFATGCVTIPWQNEMIESGCFKDLNEYEDKGLSPLEKHKICSCILRPKRNFFHRLFRRAACLNIAHSEEREPTEH
Protein: Cadherin 17 (E7EN24)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MILQAHLHSLCLLMLYLATGYGQEGKFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIEREGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSLGSGSLQNDWEVSKINGTHARLSTRHTEFEEREYVVLIRINDGGRPPLEGIVSLPGIILAVVFIRIKKDKGKDNVESAQASEVKPLRS
Protein: Serine hydroxymethyltransferase (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) (bmSHMT) (Q2F5L3)
Organism: Bombyx mori (Silk moth)
Function: Interconversion of serine and glycine.
Interaction partners:
- Aminomethyltransferase.
- GARS_C domain-containing protein.
- ATP-grasp domain-containing protein.
- Glycine cleavage system P protein
- methenyltetrahydrofolate cyclohydrolase
- MGS domain-containing protein.
- Uncharacterized protein.
- Glycine cleavage system H protein
- Glycine cleavage system H protein
- Uncharacterized protein.
Sequence:
MSAKLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDLESKINQAVFPGLQGGPHNHAIAAIATAMKQATTTEFVEYQKQVIKNAQRLCEGLISRGYSIATGGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALTTRGLKEADIDKVVDFIDRALKIGLEIIKVSGLKLVDFNKAIEENAEFKKKIENLKEEVENYSKSFPLPGFDKY
Protein: Cysteine peptidase C (CPC) (EC 3.4.22.-) (E9ADT5)
Organism: Leishmania major
Interaction partners:
- Clathrin heavy chain
- Uncharacterized protein
Sequence:
MALRAKSALCLVAVFALLLATTVSGLYAKPSDFPLLGKSFVAEVNSKAKGQWTASADNGYLVTGKSLGEVRKLMGVTDMSTEAVPPRNFSVEELQQDLPEFFDAAEHWPMCLTISEIRDQSNCGSCWAIAAVEAISDRYCTFGGVPDRRMSTSNLLSCCFICGLGCHGGIPTVAWLWWVWVGIATEDCQPYPFDPCSHHGNSEKYPPCPSTIYDTPKCNTTCERSEMDLVKYKGSTSYSVKGEKELMIELMTNGPLELTMQVYSDFVGYKSGVYKHVLGEFLGGHAVKLVGWGTQDGVPYWKVANSWNTDWGDKGYFLIQRGNNECKIESGGVAGIPAQE
Protein: Chromosome 10 open reading frame 90 (A0A0A0MSX2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
Sequence:
MLKLSGEGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFLPIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEV
Protein: Ras-related protein Rab-35 (Q9U2C3)
Organism: Caenorhabditis elegans
Interaction partners:
- UDENN domain-containing protein
- Rab-GAP TBC domain-containing protein
- Arf-GAP with ANK repeat and PH domain-containing protein cnt-1
- ADP-ribosylation factor 6
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit 10
- TBC1 domain family member 13
- Rab GDP dissociation inhibitor
- Rho-GAP domain-containing protein
- Tumor susceptibility gene 101 protein
Sequence:
MAGTRDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSENYITTIGVDFKIRTMDINGQRVKLQIWDTAGQERFRTITSTYYRGTHGVVVVYDVTNGESFGNVKRWLQEIENNCDSVQKVLVGNKCEENERRVVLESDARNYAQSMNISFFETSAKEDKNVEPMFTCITSLVLTAKLANPQSASKDQSRTGGVSLKDNSGSTNQKKKCKCG
Protein: LP14436p (Muscarinic acetylcholine Receptor, C-type) (Q9W3V5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Muscarinic acetylcholine receptor DM1
Sequence:
MAFTSSSSPAWDYRSSPEALGVVPFLWQHQNATETPTEITLQATSFGAGHLLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVGLALPYHLVFYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIFNWCLGALVALLPVFWNRWPDAQACEFDEVLAPGYIAGVITPGFVIIWICMFLVYWRIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGFRRAFVQTLCCRTARQCEDQLPADSKHRMEATSSSQEIKPKATQ
Protein: Uncharacterized protein PB1E7.01c (Q9C108)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MEQKVSADVLLNKYQTSISITKNLINSWLGNENTSVSSDEKNDDPPLQARPPRLGLGASRKDQSENSWVTSKNEKLKSLPPALKKKIERQLQKKKEAEKIEGGKNHDNLKRKLNKVGDELNEQQSDTDDDDDDSKARITSRSKRANAQSSGFDIYKKLGKKKR
Protein: Eosinophil-associated ribonuclease 10 (Eosinophil-associated, ribonuclease A family, member 10) (Ribonuclease A f2) (Q923L6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGPKLLESRICLLLLLGLVLMLASCLGQTTSQWFAIQHINNNANLQCNVEMQRINRFRRTCKGLNTFLHTSFANAVGVCGNPSGLCSDNISQNCHNSSYRVHITVCNITSWRRTPYTQCRYQAKRSLEYYTVACDPRTPQDSPMYPVVPVHLDGTF
Protein: Schlafen-like protein 1 (SLFL-1) (SLFN-like 1) (21U-RNA biogenesis fouled up protein 1) (PUCH complex member slfl-1) (Protein tofu-1) (O17608)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31216475}.
Interaction partners:
- Schlafen-like protein 2
- K Homology domain-containing protein
- Twenty One u-rna
- Embryonic developmental protein tofu-6
- Twenty One u-rna
- Ubiquitin-like protease family profile domain-containing protein
- Protein tost-1
- Enhancer of rudimentary homolog 2
- piRNA biogenesis factor prde-1
- Protein pid-3
Sequence:
MAALFEENDSYSDSENEEDFSGFLSEIEENENEDEFENDDEFEDDDELENVDELEDDELSSEEVDIPSENEVIVELHDGQAEVEESLLDALLGKALAGDQMNSRIEGLFEDLDSSVEPDIIDRSELEDVDSGISVGAVSSSSAETQASDAKCKNKDAFDMSSLKKYMQYITEEEHAVSVEDIPDFASKKNVYGTSFNVRNGIMSRPPRFEFARHDQRWIDSCVSMAYEKDKTLKELITLGKLTTTVKAGAKIEFRTKFTDVHIRSADEINLMETHDIQQIIRDALNSKRLAVVLFGIGKDGKVTGCHMGPGQQDNLRLALDTAVQTEFAPPIENILDVVDMNFVPVEEMDETFLIVIRVKQLRNQVYRLESSV
Protein: NAC domain-containing protein 1 (ANAC001) (Protein NTM1-like 10) (Q0WV96)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q949N0}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000250|UniProtKB:Q949N0, ECO:0000255|PROSITE-ProRule:PRU00353}. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon specific stress or signal, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP). {ECO:0000250|UniProtKB:Q949N0}.
Interaction partners:
- Protein ARV 1
- glucan endo-1,3-beta-D-glucosidase
- ELM2 domain-containing protein
- AT1G22750 protein
Sequence:
MEDQVGFGFRPNDEELVGHYLRNKIEGNTSRDVEVAISEVNICSYDPWNLRFQSKYKSRDAMWYFFSRRENNKGNRQSRTTVSGKWKLTGESVEVKDQWGFCSEGFRGKIGHKRVLVFLDGRYPDKTKSDWVIHEFHYDLLPEHQRTYVICRLEYKGDDADILSAYAIDPTPAFVPNMTSSAGSVVNQSRQRNSGSYNTYSEYDSANHGQQFNENSNIMQQQPLQGSFNPLLEYDFANHGGQWLSDYIDLQQQVPYLAPYENESEMIWKHVIEENFEFLVDERTSMQQHYSDHRPKKPVSGVLPDDSSDTETGSMIFEDTSSSTDSVGSSDEPGHTRIDDIPSLNIIEPLHNYKAQEQPKQQSKEKVISSQKSECEWKMAEDSIKIPPSTNTVKQSWIVLENAQWNYLKNMIIGVLLFISVISWIILVG