wanglab/gogpt-training-data huggingface dataset:
Protein: Protein CTLA-2-alpha (Cytotoxic T-lymphocyte-associated protein 2-alpha) (P12399)
Organism: Mus musculus (Mouse)
Function: Not known, expressed in activated T-cell.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Protein CTLA-2-beta
Sequence:
MMVSICEQKLQHFSAVFLLILCLGMMSAAPPPDPSLDNEWKEWKTKFAKAYNLNEERHRRLVWEENKKKIEAHNADYEQGKTSFYMGLNQFSDLTPEEFKTNCYGNSLNRGEMAPDLPEYEDLGKNSYLTPGRAQPE
Protein: Uroporphyrinogen decarboxylase 2, chloroplastic (UPD2) (URO-D2) (EC 4.1.1.37) (O22886)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Coproporphyrinogen-III oxidase 1, chloroplastic
- Protoporphyrinogen oxidase 2, chloroplastic/mitochondrial
- Coproporphyrinogen-III oxidase 2, chloroplastic
- Protoporphyrinogen oxidase 1, chloroplastic
- Porphobilinogen deaminase, chloroplastic
- Uroporphyrinogen-III synthase, chloroplastic
- S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase, chloroplastic
- Ferrochelatase-1, chloroplastic/mitochondrial
- Uroporphyrinogen decarboxylase 1, chloroplastic
- Ferrochelatase-2, chloroplastic
Sequence:
MSILQVSTSSLSSSTLLSISPRKSLSSTKSCRIVRCSVEGTTVTERKVSATSEPLLLRAVKGEVVDRPPVWLMRQAGRYMKSYQTLCEKYPSFRDRSENADLVVEISLQPWKVFKPDGVILFSDILTPLSGMNIPFDIVKGKGPIIFNPPQSAADVAQVREFVPEESVPYVGEALRRLRNEVNNEAAVLGFVGAPFTLSSYVIEGGSSKNFTQIKRLAFSQPKVLHALLQKFTTSMITYIRYQADSGAQAVQIFDSWATELSPVDFEEFSLPYLKQIVEAVKQTHPNLPLILYASGSGGLLERLARTGVDVVSLDWTVDMAEGRDRLGRDIAVQGNVDPGVLFGSKEFITSRIHDTVKKAGRDKHILNLGHGIKVGTPEENVAHFFEVAQEIRY
Protein: Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (EC 3.2.2.6) (X-linked interleukin-1 receptor accessory protein-like 1) (P59824)
Organism: Rattus norvegicus (Rat)
Function: May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:18801879}; Single-pass type I membrane protein {ECO:0000269|PubMed:18801879}. Cytoplasm {ECO:0000269|PubMed:18801879}. Cell projection, axon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=May localize to the cell body and growth cones of dendrite-like processes.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase delta
- Interleukin-1
- Receptor-type tyrosine-protein phosphatase S
- Neuronal calcium sensor 1
- Receptor-type tyrosine-protein phosphatase F
- SLIT and NTRK-like family, member 3
- Leucine-rich repeat and fibronectin type-III domain-containing protein 4
- Leucine-rich repeat-containing protein 4B
- SLIT and NTRK-like family, member 2
- SLIT and NTRK-like family, member 1
Sequence:
MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSVDIKKYQVLVGEPVRIKCALFYGYIRTNYTLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIKEVKEDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGGSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAILLLLVCSVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWHGPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTALATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQRPQTKSSREPNPDEAHTNSAILPLLARETSISSVIW
Protein: Protein TOC75, chloroplastic (75 kDa chloroplast outer envelope protein) (75 kDa translocon at the outer-envelope membrane of chloroplasts) (Import intermediate-associated protein of 75 kDa) (Q43715)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: Mediates the insertion of proteins targeted to the outer membrane of chloroplasts. Required for the import of protein precursors into chloroplasts. Forms the voltage-dependent preprotein translocation channels (hydrophilic beta barrel) of the TOC complex in the chloroplastic outer membrane. The narrowest inner diameter of this channel is approximately 14 Angstroms.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000269|PubMed:7781598, ECO:0000269|PubMed:7973649, ECO:0000269|PubMed:8953773}; Multi-pass membrane protein {ECO:0000269|PubMed:7781598, ECO:0000269|PubMed:7973649, ECO:0000269|PubMed:8953773}.
Interaction partners:
Sequence:
MRTSVIPNRLTPTLTTHPSRRRNDHITTRTSSLKCHLSPSSGDNNDSFNSSLLKTISTTVAVSSAAASAFFLTGSLHSPFPNFSGLNAAAGGGAGGGGGGSSSSGGGGGGWFNGDEGSFWSRILSPARAIADEPKSEDWDSHELPADITVLLGRLSGFKKYKISDILFFDRNKKSKVETQDSFLDMVSLKPGGVYTKAQLQKELESLATCGMFEKVDMEGKTNADGSLGLTISFAESMWERADRFRCINVGLMGQSKPVEMDPDMSEKEKIEFFRRQEREYKRRISSARPCLLPTSVHEEIKDMLAEQGRVSARLLQKIRDRVQSWYHEEGYACAQVVNFGNLNTREVVCEVVEGDITKLSIQYLDKLGNVVEGNTEGPVVQRELPKQLLPGHTFNIEAGKQALRNINSLALFSNIEVNPRPDEMNEGSIIVEIKLKELEQKSAEVSTEWSIVPGRGGRPTLASLQPGGTITFEHRNLQGLNRSLTGSVTTSNFLNPQDDLAFKMEYAHPYLDGVDNPRNRTLRVSCFNSRKLSPVFTGGPGVDEVPSIWVDRAGVKANITENFSRQSKFTYGLVMEEIITRDESNHICSNGQRVLPNGAISADGPPTTLSGTGIDRMAFLQANITRDNTRFVNGTIVGSRNMFQVDQGLGVGSNFPFFNRHQLTVTKFLQLMSVEEGAGKSPPPVLVLHGHYGGCVGDLPSYDAFTLGGPYSVRGYNMGEIGAARNILELAAEIRIPIKGTHVYAFAEHGTDLGSSKDVKGNPTVVYRRMGQGSSYGAGMKLGLVRAEYAVDHNSGTGAVFFRFGERF
Protein: PGC-1 and ERR-induced regulator in muscle protein 1 (PPARGC1 and ESRR-induced regulator in muscle 1) (Peroxisome proliferator-activated receptor gamma coactivator 1 and estrogen-related receptor-induced regulator in muscle 1) (Q149B8)
Organism: Mus musculus (Mouse)
Function: Regulates the expression of selective PPARGC1A/B and ESRRA/B/G target genes with roles in glucose and lipid metabolism, energy transfer, contractile function, muscle mitochondrial biogenesis and oxidative capacity. Required for the efficient induction of MT-CO2, MT-CO3, COX4I1, TFB1M, TFB2M, POLRMT and SIRT3 by PPARGC1A. Positively regulates the PPARGC1A/ESRRG-induced expression of CKMT2, TNNI3 and SLC2A4 and negatively regulates the PPARGC1A/ESRRG-induced expression of PDK4.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23836911}. Nucleus {ECO:0000269|PubMed:23836911}. Note=Shows a nuclear localization in the presence of PPARGC1A.
Interaction partners:
- Steroid hormone receptor ERR1
Sequence:
MDNFQYSVQLSDREWAEFSATADECGLLQADLASGDEPLSSDIDQGDSSGSSPPGPPPLFTGQLVSQGRGQQSRELEDVAAQQLVSRSQCEPVLALEASHQVAGTSTQSEAPLFPSLDSVCPGQALSFPGPATCRDKMQRLLQGPAPSSPSKAPHSPESPGHSDNPQSSPDSLEASPRNPGRKKRRAVGAKGTKHSGSLDSAATQMSSPQLTRPKEALMSGTLMAKAQQDKPQPDSTSPEQMAREESGLDLSTPILITEQDQIRKTSRAALHVVSKPVQEVHPDVPMASPNVSTRASKPQPDVALPKPASKPQSDIASSTHPFTPDVSLSTLAFKCQPNTNQSTPASEPDMALSTPASEPDTALSTPASEPDTALSTPASEPDTALSTPASRSQLVKAEFASACTPGLHVDLSAAGSEIKPEVSSSMPAAVDVLRTDLPRSVSKTESKESVSIPVKPSLSPISQAEAAMVDTGVSVPPGGSIEKPAGQFSAGSSGESCLGPVQAPKKKKVRFSMAIPSHEDSGSGEPTGSPFLTPEQPPVPRTAAGSRGGSAAWDAVAVAPRLPQPRILKHLPPPVSSVSAEAESGNCFAVTLPEAYEFFFCDTIEEEDEDVEDEEAASQALDEVQWPDTCEFFFRDSRAQRSRCQRGHSPVSPPRADTVAPVPPEGLVPISIPEVYEHFFTEEGFGHRQPAATPMQTSELSREGGLEASTKPVSPTAEHLSLTVRKAGELRSPLTSFTFSQNDMCLVFVAFATWAVRTSDLQAPDAWKTVLLANIGTISAIRYFRRQVGRGHSGRPRSSSSSNPSC
Protein: MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78) (P27448)
Organism: Homo sapiens (Human)
Function: Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1. Phosphorylates PKP2 and KSR1.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21145462}; Peripheral membrane protein {ECO:0000269|PubMed:21145462}. Cell projection, dendrite {ECO:0000269|PubMed:23666762}. Cytoplasm {ECO:0000269|PubMed:23666762}.
Interaction partners:
- Kinase suppressor of Ras 1
- M-phase inducer phosphatase 3
- 14-3-3 protein zeta/delta
- 14-3-3 protein beta/alpha
- 14-3-3 protein gamma
- Microtubule-associated protein 4
- 14-3-3 protein epsilon
- 14-3-3 protein eta
- Serine/threonine-protein kinase MARK2
- Proteinase-activated receptor 1
Sequence:
MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
Protein: ABC transporter F family member 2 (Q8T6B7)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- 50S ribosomal protein L20
- Large ribosomal subunit protein bL27m
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein uS8
Sequence:
MAKKGGKNNKSKKEVTPPTSDVEDEVQDKFKEMRLNAFTATGALASKESSRDVKIEQVTLTFHGKELLSDTTVEINFGRRYGLIGQNGCGKSTFFQCLAVRELPIPEHIDIFHLSEEAHPSERTALQSVIDDAEKEVKRLEVLEERLLEEQGPESEELFDVYERLENLDPTTFVPRASEILIGLGFTSQTMLKKTKDLSGGWRMRVSLAKALFIKPTLLLLDEPTNHLDLGACVWLEDYLANYDRSLIIISHSQDFLNAVCTNIIHMTQSKLKYYGGNYDNFVKTKAELEVNQMKAYHKQQEEIAHIKSFIASCGTYSNLVRQGKSKQKIIDKMEEAGLVERVQEDKIFNFSFPPCGELAPPIMHFDNVTFSYSGKEADVLYRNLDLAIDLDSRIALVGPNGAGKSTLLKLMVGQISPTQGFIKKHSHLKMARYHQHAHEVLDLTATPLDFVRSKFAHMNKDTEEWRREIGRFGVTGKAQTEAIGCMSDGIKSRLIFCLMALENPHLLLLDEPTNHLDMECIDSLALAINSFPGGMILVSHDFRLISQVAKEIWVCDNKTITKWAGDITSYKNHLKAQMRDLTKQGALASLKK
Protein: Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Q95R68)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004648, ECO:0000256|RuleBase:RU368089}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004648, ECO:0000256|RuleBase:RU368089}.
Interaction partners:
Sequence:
MARNTGSSSGSTPAASSSGSSAAAAAAAAAAAAAASNAKQKQRSPRFSLSSNLILDKWKTMIGCVCLAIASYFGYLGYLETRVNTPFDHQKMVVHAGLEQPDRYWGSYRPLTYFGMKTRDPHSLVMGLMWYTPSNLGPGGQGIRHWCEQGDKLDSYGWTHHDGRSFGVQEIQDLPFELKTSFVKYPEGKQYGGDWTARISVRNTTRAWDKSISLIWYVALDERTNGHIKYVSDDKSPEPGVYGEAQGLGEFQVRFHAVKGKILHKSYLSTVAPSLAKLKDTLFSHFRAFADKRGNRFIGLPGEIVSQNGLPSSNPEPNFIAIQITAEVDFTLDITYQSTSGFSLGESIPKPPTGRAYQDSLQAKIAQFEQRFEDRFQLKQKGHSPEEVRFARNALSNLLGGIGYFYGSSRVQSVYTKNPVPYWKAPLYTAVPSRSFFPRGFLWDEGFHGLLISAWDIDIELDIICHWFDLLNVEGWIPREQILGVEALAKVPEEFVTQRNSNANPPTFFLTLKKLLTSHRAELSQNGRLATLERLYPRVQAWFNWFNTTQRGEVLGTYLWRGRNATTTRELNPKSLSSGLDDYPRASHPTDKERHLDLRCWIALAAGVMAELSTLLGKDDAKYYETASYLTDNVRLNRLHLAPYSEQYADWGLHTDQVKLKRPPSMAPQQQQRHHHQYYQLPEMQRVTGELPTYQFVDSAFGYVSLFPLLLEQLDHDSPYLTKLLNDLRDPEQLWTNYGLRSLSKRSPLYMQRNTEHDPPYWRGPIWININYLAAKALHHYGKIDGPNAALARQIYAELRDNLVGNILRQYKRSGYLWEQYDDTSGEGKGCNPFTGWTATVVLLMAEQF
Protein: Small ribosomal subunit protein eS26B (40S ribosomal protein S26-B) (P39939)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein eS24A
- Small ribosomal subunit protein eS25B
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS9A
- Small ribosomal subunit protein uS13A
- Large ribosomal subunit protein eL38
- Small ribosomal subunit protein uS12A
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS4B
- Small ribosomal subunit protein eS19A
Sequence:
MPKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPPQRPRFNRDNKVSPAAAAKKAL
Protein: Translation initiation factor IF-2 (P0A705)
Organism: Escherichia coli (strain K12)
Function: One of the essential components for the initiation of protein synthesis. May protect N-formylmethionyl-tRNA(fMet) from spontaneous hydrolysis. Promotes N-formylmethionyl-tRNA(fMet) binding to the 30S pre-initiation complex (PIC). Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. Upon addition of the 50S ribosomal subunit, IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:1764105}.
Interaction partners:
- 30S ribosome-binding factor
- tRNA pseudouridine synthase B
- DNA-directed RNA polymerase subunit beta
- Transcription termination/antitermination protein NusA
- Large ribosomal subunit protein uL2
- Elongation factor G
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS2
- Ribosome maturation factor RimP
- Small ribosomal subunit protein uS3
Sequence:
MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
Protein: Ras GTPase-activating-like protein IQGAP2 (Q13576)
Organism: Homo sapiens (Human)
Function: Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
Interaction partners:
- Cell division control protein 42 homolog
- Ras-related C3 botulinum toxin substrate 3
- Calmodulin-1
- Ras GTPase-activating-like protein IQGAP1
- Ras-related C3 botulinum toxin substrate 2
- Ras GTPase-activating-like protein IQGAP3
- Calmodulin-like protein 3
- Calmodulin-like protein 5
- Ras-related C3 botulinum toxin substrate 1
- Calmodulin-like protein 4
Sequence:
MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMESIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAVIAINEAVEKGIAEQTVVTLRNPNAVLTLVDDNLAPEYQKELWDAKKKKEENARLKNSCISEEERDAYEELLTQAEIQGNINKVNRQAAVDHINAVIPEGDPENTLLALKKPEAQLPAVYPFAAAMYQNELFNLQKQNTMNYLAHEELLIAVEMLSAVALLNQALESNDLVSVQNQLRSPAIGLNNLDKAYVERYANTLLSVKLEVLSQGQDNLSWNEIQNCIDMVNAQIQEENDRVVAVGYINEAIDEGNPLRTLETLLLPTANISDVDPAHAQHYQDVLYHAKSQKLGDSESVSKVLWLDEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKIQSWFRMATARKSYLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHSKKLNKKKGGEMEILNNTDNQGIKSLSKERRKTLETYQQLFYLLQTNPLYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLGEVPTVESFLGEGAVDPNDPNKANTLSQLSKTEISLVLTSKYDIEDGEAIDSRSLMIKTKKLIIDVIRNQPGNTLTEILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRNLRTLEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFYEEQINYYDTYIKTCLDNLKRKNTRRSIKLDGKGEPKGAKRAKPVKYTAAKLHEKGVLLDIDDLQTNQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK
Protein: FKBP12-associated protein 1 (P53971)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May play a role in transcription regulation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10998178}. Nucleus {ECO:0000269|PubMed:10998178}. Note=Translocates to the nucleus in response to rapamycin.
Interaction partners:
- FK506-binding protein 1
- Uncharacterized protein YIL161W
- Small ribosomal subunit protein eS12
- Small ribosomal subunit protein eS28A
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS2A
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein eS6A
Sequence:
MTEHESLGLEQNQDGGDTYRHHNLSDGCISSVEDANEQPSSYEEESDDDMQYYERAIQEISSGDSYVCMICTVEMDYTCQMFACKRCYRVFDYGCIREWALKSTEKTVDRIWKCPNCYYVSKRVPVKNRPTCWCGKVVNPDPNPLDPNSCGQTCNASTCMHGCSKICHLGPHPECTRMVEIMCHCGKHSKSIFCYQSKVMKKNFNCQEVCGLPLSCSIHTCKKKCHPGLCGPCPEMIISKDSPKKQIKCYCGNHTRANIKCSETKFPKSGKSSKDENGNRWIGVFACADNRVVDYSCRKHSFIESCISPPTINGEKACPFLPSSLKTCPCGRTALEELTKPRKHCDDPIPTCDSRCGKPLKCGKHSCPFTCHDKACMEPCLQIDSVKCACEQSTFSVPCGFQGRPRCNIKCESLMSCRRHRCTDRCCSGRPSAIRRKKNLFRTQDLLDESLVEAKHICLKPCNLTLSCGIHKCQRKCHPGKCPPCLESDSNDLVCPCGNTVVPAPVRCGTKLPTCNHPCIKVVRGESTCGHKPMPHTCHSLDVSCPPCTETVFKPCKCGKKTKVRTVCFQTDVSCGIKCGIPLSYCYHTCQKTCHLPGNCQKVCKQTCGQKRLNCNHECPKPCHGKTECPDLPCATLVKIYCKCGRIKKSVTCGAKSDRVSVTESSVLDCNEECEALKRLKELKEAFGIKEETNNFTSNELDALKKLVSVATTFEELQLPFTEAALSVYSKQERWCSQIEAILNKLMDDKTRSSLHFKPMRPPQRHFIRELAKAYGLYSESQDREPMRSVFIKKEDNGASNKPVLSLAEAYPLYESFKQLQKERKAQEFQARTTAKLINFEVQDTEPKVEVAKKNGFLVQNLVAGNTAEDLRRFFEPHLKHTLVVNPQYLILDDGKTALVYPENYETASVNTERDMELLVGHFDFMAKEAFLADSISLCSTEEELERRLDTPVIQEDSPVMDNNT
Protein: Normal mucosa of esophagus-specific gene 1 protein (Q810Q5)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Cytochrome c oxidase subunit NDUFA4
Sequence:
MGVFQILMKNKELIPLAFFISVAATGATSFALYALKKTDVVIDRKRNPEPWEMVDPTQPQKLITINQQWKPVEELQKVRRATR
Protein: Protein NDL3 (Protein N-MYC DOWNREGULATED-LIKE 3) (Q9ZUN1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in a signaling pathway that modulates root auxin transport and auxin gradients. Acts partially by positively regulating the auxin carrier PIN2 and AUX1. Acts, together with GB1 as positive regulator of meristem initiation and branching. GB1 and NDL3 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots, which regulates organ and lateral meristem formation by the establishment and maintenance of auxin gradients.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9FJT7}.
Interaction partners:
- Guanine nucleotide-binding protein subunit gamma 1
- Guanine nucleotide-binding protein subunit beta
- Small ribosomal subunit protein eS27y
- Expressed protein
- Guanine nucleotide-binding protein subunit gamma 2
- Regulator of G-protein signaling 1
Sequence:
MVGLNNAVSLDIEEICNGGKEHHVKTCHGSVSVVVYGDQEKPALITYPDVALNYMSCFQGLFLCPEAVSLLLHNFCIYHISPPGHEFGAAPVCSNDPSPSVEDLADQILEVLNFFSLEAVMCMGITAGAYILSLFAIKHKERVLGLILISPLCKAPSWSEWFYYKVVSNLLYYYGMSGLLKDIFLQRYFSKEARGSSEVPERDVVHECRRLLGERHGSSLMRFLEAVNRRHDLTDGLKSLKCRTLIFVGDQSPFHSETLHMVTALDRKYSALVEVQACGSMVTEEQPHAMLIPMEFFFMGFGLYRPGRVSDSPRSPLSPSCISPELLSPESLGLKLKPIKTRVPTKC
Protein: Ubiquitin-protein ligase E3A (EC 2.3.2.26) (A0A8I5ZM14)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR037201}. Nucleus {ECO:0000256|PIRNR:PIRNR037201}.
Interaction partners:
Sequence:
MRILKYTTILRMRKLRHRKAKKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLCDPHPSKKGASSAYLENSKGASNNSEIKMNKKEEFKEVDYLTEEKVYEIYEFCREREDYSPLIRVIGRIFSSAEALVQSFRKVKQHTKEELKSLQEKDEDKDEDEKEKAACSAAAMEEDSEASSSRMGDSSQGDNNVQKLGPDDVTVDIDAIRRVYSSLLSDEKIETAFLNALVYLSPNVECDLTYHNVYTRDPNYLNLFIIVMENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYSADQIRRMMETFQQLITYKVISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGDVDTNHNEEDDEEPIPESSELTLQELLGEERRNKKGPRVDPLETEIGVKTLDCRKPLISFEEFINEPLNDVLEMDKDYTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDEATRLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFCDLGDSHPILYQSLKDLLEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVSLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRESVVIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGML
Protein: EvpP (A8YQR4)
Organism: Edwardsiella tarda
Interaction partners:
Sequence:
MSILNSELDWSHVGSISTGPGTVVSDAFNISYGLPTKELLPAGTALYKFNGFSSLARPPITDDTPLSPWWSPVQPFRHDGGLQQRMLVAKLNGVSMREWGRLTSVIKENWSSLDHLLEIVLKVPVYAWFGGFKGMSRIDNGMPSKRNITLEQKGRGSNLPGGATQFYIPNLTVGHISSHNFSALK
Protein: Possible oxygenase (P95277)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH
- Probable ferredoxin/ferredoxin--NADP reductase
- NADPH-ferredoxin reductase FprA
- Glutamate synthase small chain
- Epoxide hydrolase B
- 3,4-dihydroxy-2-butanone-4-phosphate synthase
- Possible monooxygenase
- Probable multifunctional mycocerosic acid synthase membrane-associated Mas
- Phthioceranic/hydroxyphthioceranic acid synthase
- Mycoketide-CoA synthase
Sequence:
MAVRQVTVGYSDGTHKTMPVRCDQTVLDAAEEHGVAIVNECQSGICGTCVATCTAGRYQMGRTEGLSDVERAARKILTCQTFVTSDCRIELQYPVDDNAALLVTGDGVVTAVELVSPSTAILRVDTSGMAGALRYRAGQFAQLQVPGTNVWRNYSYAHPADGRGECEFIIRLLPDGVMSNYLRDRAQPGDHIALRCSKGSFYLRPIVRPVILVAGGTGLSAILAMAQSLDADVAHPVYLLYGVERTEDLCKLDELTELRRRVGRLEVHVVVARPDPDWDGRTGLVTDLLDERMLASGDADVYLCGPVAMVDAARTWLDHNGFHRVGLYYEKFVASGAARRRTPARLDYAGVDIAEVCRRGRGTAVVIGGSIAGIAAAKMLSETFDRVIVLEKDGPHRRREGRPGAAQGWHLHHLLTAGQIELERIFPGIVDDMVREGAFKVDMAAQYRIRLGGTWKKPGTSDIEIVCAGRPLLEWCVRRRLDDEPRIDFRYESEVADLAFDRANNAIVGVAVDNGDADGGDGLQVVPAEFVVDASGKNTRVPEFLERLGVGAPEAEQDIINCFYSTMQHRVPPERRWQDKVMVICYAYRPFEDTYAAQYYTDSSRTILSTSLVAYNCYSPPRTAREFRAFADLMPSPVIGENIDGLEPASPIYNFRYPNMLRLRYEKKRNLPRALLAVGDAYTSADPVSGLGMSLALKEVREMQALLAKYGAGHRDLPRRYYRAIAKMADTAWFVIREQNLRFDWMKDVDKKRPFYFGVLTWYMDRVLELVHDDLDAYREFLAVVHLVKPPSALMRPRIASRVLGKWARTRLSGQKTLIARNYENHPIPAEPADQLVNA