wanglab/gogpt-training-data huggingface dataset:
Protein: Malic enzyme (Q385M4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Malate dehydrogenase
- fumarate hydratase
- fumarate hydratase
- malate dehydrogenase
- Pyruvate kinase
- Malate dehydrogenase
- pyruvate dehydrogenase
- malate dehydrogenase
- Pyruvate dehydrogenase E1 component subunit beta
- Pyruvate, phosphate dikinase
Sequence:
MTHQSTDVSGPCGAAVLTNRYLNRGTAFTIEERKQLHILGQLPTVVETLEQQVKRAYNQMKSCGKPIDQYQQLAALHATNTTLYYATIFAHLEETLPIIYTPTVGEACQRYSSLLFRERGLYLCRTYKGMFRTIMRDSGYENPKVVVITDGSRILGLGDLGANGVGISIGKCSLYVAGAGINPKNVVPVVLDAGTDNAAMLSDDNYIGVRQKRPSDEDFYALLDEFMEAASEAWPEAVIQFEDFSNNHCFDMLERYQNKYRCFNDDIQGTGAVIAAGFLNAVKLSKVDPLDHRIVVFGAGSAAIGVVDNIAELTAQLYNLKSDDVKKTFYLVDTKGLVTTTRGDKLASHKVSLARTDVSAEDSAKLKTLEDVVNFVKPTTLLGLGGVGPVFTESMVKGILNNTKRPIIFPLSNPTSKSEITADNAFKWTDGKAIVASGSPFPPTTLNGKTYKASQGNNLYVFPGIGLGCAIAKPAYIPNDLLIAASRCLNGLVSKVGLEDGSLYPPLSDIHNISANIATDVIMEAQRLKIDNNSSLPRTRAELMDYVKHAMWKPEYPTGILPDE
Protein: Auxin-responsive protein IAA20 (Indoleacetic acid-induced protein 20) (Q5VRR0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Ubiquitin-related modifier 1 homolog
- Ubiquitin-like protein ATG12
- Os10g0560450 protein
- Autophagy-related protein 3.
- Auxin response factor 11
- Molybdopterin synthase catalytic subunit
- Os01g0694200 protein.
- Os02g0517366 protein
- Auxin response factor 1
- Transport inhibitor response 1-like protein Os05g0150500
Sequence:
MELELGLRLALPSPSPSPATATAAGSELDLLNSAPGSCRKRGFEEALGGFKTDDDNDDGNGRGGDGDSDGEMGNKRRKLVGWPPVKCLHRRRDGGCGGGYVKVKMEGLAIGRKLDLSILGSYAELLDTLHLMFPSTNQEDGHDRRRRHPYAVTYEDGEGDWMQVGDVPWEAFAKSVKRLKILV
Protein: 6 protein (SsDNA binding protein) (O41928)
Organism: Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68)
Interaction partners:
Sequence:
METTNVCSQAPLGPAGYIYYQLVDDFPLEEASLLSTNFTSAKACLLPLVTGLTVEPGFNFNVKAPCQKIMFESLTVKPTKYFNHAIVFHNSNKIPPIFHGRGLEQLCEATRLMFGFSSFKPDASKGQWKSSTHLPQNPEKYIGWVVVAESFKERLICGELAMLSAPMKTVTINNKLCFKVPLHDTRFLSSDQLLPFYDENVSRIMYESYYTNVAQAVRIRDVTGLIEALQERAVTEQYKTAKLASLKTYPAENCGAGNLEYAVIDAAVSELAVSHGLAFLEAPQEESPIQNYVQWPMFSEDATPEGRIKALQEWNAKMAIHVHAQVLSANSVLYVTKVGQSAGKAVGGKQDDMFLGRYYMQHGLGHLNVQTRDENNTVVFPGVPDSCMNGSQYTVHHLAYAASMSPHILARLCYYLQMCQNQRLASTPQGTTVPAYVTTTANTSMCDLCGGDLPAVCLHTLFFRLRDRFPQVLATQKRDPYVVTGIAGPHNDMEILGNFGSFKEKDDDQENGQRYSYWQLNANLTERLEEIGVTASTPACQLITDVDSFLTVFKKIDAIVDEETIRFNDGLVRNNINYKESVKSIAHVLQLQCNTNWLPPCPIIHNLFTRSFFTILQDMSFPLCVTHHTENPLNYGTVSTWMSNHFQNLWSNFKSIWFDKGLLTCSDMRVVHTETSSDMENLAADLPKQRCAIRLSRAQIFAPKALKIKNRIIFSNSSSTESLSASFVKAGKAENPITAGPYMHFLTQLHKQLFPTTKTGAYYIWQTFMSSKKLPQAGSTNAKKLSEFISYLMTSSLAHDEVNVLDYVPTTLMAYAKQRLNNAILRLCGQTQFYATTINFLQPTILSMPSLDYPHVAGPVPVQDLTTYMDMTRDQSATVIQSSCREDPAAVCKMRPIVTIPMMVNKYSGSNGNNSIFQSGNMGYFMGRGVDRKLLPDIPRMRKHVNTSMRRRYAFASPMTESLLTQPGKGTVRTYQLEKTRKIIHDIIASGNAEPENLVLELVKCLGHECATLTSDDVEFYLGEFSFMVNDVMEVLETLKASGCAFSEESVQALLPTSSPGTSESFVEVTDNIITSLPEISVTQFTAAPPKRRRIATFEDIDL
Protein: PH domain-containing protein (G5EC19)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEEFDENSRKSLKKQKKEYRDEKKRVNDELLSALRDPTVVVMADTLKIRGALKRWNRYYCVLKPGLLILYKHKKADRGDWVGTVLLNHCELIERPSKKDGFCFKLFHPMDMSIWGNRGPLGQSFGSFTLNPLNTSFLICRAPSDQAGRCWMDALELSFKCTGLLKKTMNELDDKNGDSSMNDGQRDESRMSRDSDGDDTRELAVSETDAEKHFQEIDDVQDEDHEDGKMSETSDTIREAFTESAWIPSPKEVFGPDGSLTEEVGEENKSLIWTLLKQIRPGMDLSKVVLPTFILEPRSFLEKLADYYYHADLISEAVAEPDPFQRIVKVTKFFLSGFYKKPKGLKKPYNPILGETFRCKWEHPDGSTTFYMAEQVSHHPPVSSLFITNRKAGFNISGTILAKSKYYGNSLSAILAGKLRLTLLNLGETYIVNLPYANCKGIMIGTMTMELGGEVNIECEKTGYRTTLDFKLKPMLGGAYNQIEGSIKYGSDRLASIEGAWDGVIRIKGPDGKKELWNPTPEVIKTRLPRYEINMDEQGEWESAKLWRHVTEAISNEDQYKATEEKTALENDQRARAKSGIPHETKFFKKQHGDDYVYIHADYRPWDNNNDIQQIENNYVVKTISRHSKRKTGNSEQLGSDNTSEASESDEEVIEPKIKKKEIVPAKSKPITPEVADERIKEMERKFELAIRRMEAANERQSSRTLNAIQSTLLFVFVVTSVVQSIFMFFMLRK
Protein: Putative uncharacterized membrane protein C622.07 (O94597)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MASLDIHLYVKKDLTYGECVRVAKEKYKIIHRLLYISIIFLFLNYVVDIVCYVKNYNGFSFFCWVFLNLGVIGIIITVIIYYISIPKPDAESEFLNKPDSLNQNVGESQSNEPPKYTSTFMDELDKQD
Protein: Putative ligase Rv1013 (EC 6.2.1.-) (O05598)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Peptide synthetase MbtE
- Peptide synthetase MbtF
- 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
- Probable inactive lipase Rv1592c
- Putative inactive phenolphthiocerol synthesis polyketide synthase type I Pks1
- Mycocerosic acid synthase-like polyketide synthase
- Mycoketide-CoA synthase
- Probable multifunctional mycocerosic acid synthase membrane-associated Mas
- Phthioceranic/hydroxyphthioceranic acid synthase
- Phenolphthiocerol/phthiocerol polyketide synthase subunit C
Sequence:
MSRFTEKMFHNARTATTGMVTGEPHMPVRHTWGEVHERARCIAGGLAAAGVGLGDVVGVLAGFPVEIAPTAQALWMRGASLTMLHQPTPRTDLAVWAEDTMTVIGMIEAKAVIVSEPFLVAIPILEQKGMQVLTVADLLASDPIGPIEVGEDDLALMQLTSGSTGSPKAVQITHRNIYSNAEAMFVGAQYDVDKDVMVSWLPCFHDMGMVGFLTIPMFFGAELVKVTPMDFLRDTLLWAKLIDKYQGTMTAAPNFAYALLAKRLRRQAKPGDFDLSTLRFALSGAEPVEPADVEDLLDAGKPFGLRPSAILPAYGMAETTLAVSFSECNAGLVVDEVDADLLAALRRAVPATKGNTRRLATLGPLLQDLEARIIDEQGDVMPARGVGVIELRGESLTPGYLTMGGFIPAQDEHGWYDTGDLGYLTEEGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLDAGHSRESFAVAVESNAFEDPAEVRRIEHQVAHEVVAEVDVRPRNVVVLGPGTIPKTPSGKLRRANSVTLVT
Protein: Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32) (Q14392)
Organism: Homo sapiens (Human)
Function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta. Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:19651619, ECO:0000269|PubMed:19750484}; Single-pass type I membrane protein {ECO:0000255}. Cell surface {ECO:0000269|PubMed:19651619, ECO:0000269|PubMed:19750484}.
Interaction partners:
- Transforming growth factor beta-1 proprotein
- Transforming growth factor beta-3 proprotein
- Transforming growth factor beta-2 proprotein
- BRCA2-interacting transcriptional repressor EMSY
Sequence:
MRPQILLLLALLTLGLAAQHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFSSQEEVSLSHVRPEDCEKGGLKNINLIIILTFILVSAILLTTLAACCCVRRQKFNQQYKA
Protein: Selenocysteine lyase (mSCL) (EC 4.4.1.16) (Q9JLI6)
Organism: Mus musculus (Mouse)
Function: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:10692412}.
Interaction partners:
- Iron-sulfur cluster assembly enzyme ISCU
- Selenide, water dikinase 2
- Selenide, water dikinase 1
- Thioredoxin reductase 3
- Thioredoxin reductase 2, mitochondrial
- Thioredoxin reductase 1, cytoplasmic
- Frataxin, mitochondrial
- LYR motif-containing protein 4
- Selenoprotein M
- O-phosphoseryl-tRNA
Sequence:
MDAARNGALGSVESLPDRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMVRCFHEQQTLKGNMVDQHSPEEGTRPHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKRIHLNSRFPGVERLPNTCNFSIQGSQLQGYTVLAQCRTLLASVGASCHSNHEDRPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVDLIVQDLKQAVAQLEGRL
Protein: Autophagy-related protein 8 (Autophagy-related ubiquitin-like modifier ATG8) (Pexophagy zeocin-resistant mutant protein 2) (Q8NJJ4)
Organism: Komagataella pastoris (Yeast) (Pichia pastoris)
Function: Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
Subcellular location: Cytoplasmic vesicle, autophagosome membrane {ECO:0000250|UniProtKB:P38182}; Lipid-anchor {ECO:0000250|UniProtKB:P38182}. Vacuole membrane {ECO:0000250|UniProtKB:P38182}; Lipid-anchor {ECO:0000250|UniProtKB:P38182}.
Interaction partners:
Sequence:
MRSQFKDEHPFEKRKAEAMRIRYKFADRIPVICEKVEKSDIPEVDKRKYLVPCDLTVGQFVYVIRKRIKIPSEKAIFIFIDDILPPTAALMSKVYEEHKDEDGFLYVLYSGENTFGDIPGVEEIE
Protein: Putative lipase YDR444W (EC 3.1.-.-) (Q04093)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
Sequence:
MPYKINRMKNSLEINETGGTLLVDERKRLRIGELYRYKFSVNKDVIKEQGLDVSHLFLRIKNEESALLRPLYLTGPYSFYIDVRPHNYNENRKFPGKEIIPFVENLKPDERFKVKILLNENSRVGDTSLYSWTIDIISQLAVTTIPKLEFSFRIGTTRKVVKKSNGLFKSIEGVSLEMWDTETLWDLPPKFPEKPVHLVIMTHGIFSNIGCDMLYMKDKIEEMTFPMDESINPNIIVRGFMGNVGKSGHGIHCLGVRVGKYVLETVDKLNKKYKVDRISFIGHSLGGPTQSMAVRYISIKRPDFFDAVKGVKPVNFITLASPFIGVIGDFPFYLSVPLDMGALGLTGRDLNLKYTPLTSKDGLYADDEVYPEHSKYILEILPQAPAKKVFESFKRRTIYANVMDDGIVPLRTAALLYLDWRSIHKVQKIRKKNKNSPTSSEFVSSDSPESSGASSPSNENGNNVGEIPAESPNKKATLQWTLPQAVIHGSKINKYKRGQTNEANSDSDNEQGVFLDGQKFEPPKEANTVLSALSVLTAAIPDQEYIKNPAVRKDEVIHDKLYHPEELPPPHYENRPIVKKLIYPNESVNRIQERIAREWQETMTWRKVLVQIQPDSHNNIVVRRRFVNLYGYVAVEHMVEHHFGSKVCSELAEDANEPKDEPNQSSQADRSNEYNEGEISKGAENAT
Protein: Protein CURVATURE THYLAKOID 1D, chloroplastic (Q8LDD3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Determines thylakoid architecture by inducing membrane curvature.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:23839788}; Multi-pass membrane protein {ECO:0000269|PubMed:23839788}.
Interaction partners:
Sequence:
MELCTRSTTIITHLPASFNGHGYLAGKSVDRISLPLQRNVASLVLQSRTLRCSRKFPGETVTEETSTGVNEFGVEDRDGVVVAAEEKNSNSEAPQAEDEETQALEFLNDIKLDSDKTYSILLYGSGAIVALYLTSAIVSSLEAIPLFPKLMEVVGLGYTLWFTTRYLLFKRNREELKTKVSEIKKQVLGSDSE
Protein: Spermidine/putrescine import ATP-binding protein PotA (EC 7.6.2.11) (Q9I6I9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Polyamine transport protein PotH
- Spermidine-binding periplasmic protein SpuE
- Putrescine transport system permease protein PotI
- Putrescine-binding periplasmic protein SpuD
- Putrescine/cadaverine-binding protein
- Polyamine transport protein PotB
- Polyamine transport protein PotC
- Probable periplasmic spermidine/putrescine-binding protein
- Probable periplasmic spermidine/putrescine-binding protein
- Putrescine/agmatine-binding protein
Sequence:
MAIASGAYKKALEGNQQPKEVLVKIDRVTKQFDETLAVDTVSLTINKGEIFALLGGSGSGKSTLLRMLAGFERPTEGRIFLDGQDITDLPPYERPINMMFQSYALFPHMSVAQNIAFGLKQDGLPKAEIDERVAEMLKLVHMTQYAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRSQMQLELVEIIERVGVTCVMVTHDQEEAMTMAQRIAIMHLGCIEQIGSPMDIYETPASRLVCEFIGNVNLFDGVLVEDVQDHAVIACPQLENPIYIGHGISTRAEDKRITYALRPEKVMISAQKPDNLEHAGHNWAQGTVYDIAYLGGHSVYYIKLASGMIVQAFMANAERHVARPTWDQSVYISWYDDSGVVLQS
Protein: Tubulin alpha chain (B5DGE8)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Gap junction protein
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Melanocyte-stimulating hormone receptor
Sequence:
MRECISVHVGQAGVQMGNTCWELYCLEHGIQPDGTMPNNKAVGSTDDSFTTFFSATGIGKYVPRAIFVDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNYARGHYTIGKEIIDQVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDFGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPSYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNSCFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNVAIGNIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDSFEEDEEGEEY
Protein: SET domain-containing protein (Q57TW0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNRGSVAGAIALKRRCHHVIDALGARTPPEAFLFRGNAYMALGQPYFALADYNTAAQVLQLSGQHQQRCQEALLRFPPHQVGVYPADNSHLHIHVHPYLNEECEVKQIDAVIGRGIVARENLKKGTVVIQRAEPWMRYPVADGLCALCTKPLPERFFTCTNPRCHEEYCSRDCRTIALSRYHSRTCRIEGLQAIELDLFSQMKSSEAATDKNSAAAQLLMLRVLAASLQQQIVPSALSEVRILSGRLLFSPAALAGKFLEIYERFTRACSTSTSIPYEEMIGVLARVTTNCFHRENCVELSLPRSLLNHSCDANVAEDAETGEMRTTQDVARGTELTINYYPQLKELNYKSRSRELERRGFVCCCSRCRRER
Protein: Nucleotide-binding oligomerization domain-containing protein 1 (A0A0K0KIB0)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Inflammasome {ECO:0000256|ARBA:ARBA00004110}.
Interaction partners:
Sequence:
MYIMDSSAEEARAGLTGHVSTVQMLTLHRELLVSQVKSTQCIMDNLLQSGFLCIEDAEIIQRAATKTDQVRKILELVQRKGVQACEYFLYILYKVYDAYIDLQPWLKEINYQPPDFVRDIPVKNTDPISRYCEKLRHELGRDTRFIASYAQQEETLLEELYTDTLMELLNDRNESLGHLEGLEQLLGEQGVFNSQAETVLVTGDAGVGKSILLQKLQRLWSKRELEQTDAMFFFKFRCRMFSTFKETDEISLRDLLFKYNCYPDQDADNEVFSYILRFPEKVLFTFDGYDEIQADLDLVNVPEVVSPEERTHPLLVLINLLCGKLLNGSRKVLTARTGTDVQSRVVRKRVALRGFSPAHLQTYTNVHFKEQEHRNLVSVQLDASPHLCGLCSIPLFCWIVFRSFKHLHSVYDDFELPEACVTLTNIFLLLSEVFFAGGAAPPPVLLKRNTRCPAVTFRAGLRPLTAFSKLALLGMERGGFVFDQEEVASCGLTDDDLKVGFLRPVSCYDACENPSTFEFLHLTLQSFLAAFSLVLDEQASVGNILKFFTECSRRGNTSCLSCVVHCIGGSSKPRGKDPFKTNEHLQYANLFLCGLLSKANASLLEHMVPAALLKRKRAVLKSYLSTSVRSHLRGLPLYSTEQEGSKVHVLPNFLWMLRCIFETGSKEVAQLTAKGVTADYIKLGYCNVFSGDCSALNFVLQHRRKRLGLDMDNNNTSDYGVKQLRPSFSKMTVVRLCVNQISDSSVEVLAEELIKHRVVEVLGLYNNHITDIGAKLIAHIIEECSKLRVVKLGSNKFTSMGGKYLASAIQKSTSIFDVGMWGNSIGDEGARAFAEALRNHPSLTNLSLSANGITSEGGRSLAEALKGNTMLRIFWLVQNELSDDVAPDLAELIRSNTGLSHLWLINNQLTVGGIRQLSEALSHNTSLKEISLKGNCLSEEEEKLFEAEGRLRFH
Protein: HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase (F4K3A9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MPNFSVNVPQLSSLYSTKTPKVRMNLCADQVFDKKLLWRDMSTKMKFPSFSAAELPDLRKSNKRRGSLRMIKCRAAGADGGRVAVGDDVFSVTTSSKYEVDYLGQSTKGDLNLKLDPLQSFGDGQATLEGPIEEVARTEAQAAENLIRELGIQGPFSAQHSPRGIFCSRTLNLRSISAIGYDMDYTLMHYNVMAWEGKAYDYCMENLKSMGFPVDGLAFDPELVIRGLMIDKEKGNLVKADRFGYVKRAMHGTKMLSNKAVSEIYGRELVDLRNQSRWEFLNTFFSVSEALAYAQMVDRLDDGFISADLGTLDYKGLYKAVAKALFRAHVEGQLKSEIMSKPELFVEPDPELPLALLDQKEAGKKLLLITNSDYHYTDKMMKHSFNKFLPNDMDWRDLFDMVIVSARKPEFFQMSHPLYEVVTGEGLMRPCFKAETGGLYSGGSAQMIESSLNVHGDEILYVGDHIYTDVSVSKVHLRWRTALICRELEEEYMALIGSRGHREELIELINQKEVVGDLFNQLRLALQRRSKGRPAQTLAATNLDDQELTETMQKLLIVMQRLDDKIGLMLETDGELFNKRWGFLSRAGLWDKSHLMRQIEKYADIYTSRVSNFLNYTPFMYFRSQEQSLAHDSPLPDAGIEN
Protein: T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (P39079)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation.
Subcellular location: Cytoplasm.
Interaction partners:
- T-complex protein 1 subunit theta
- T-complex protein 1 subunit gamma
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit eta
- Prefoldin subunit 5
- Phosducin-like protein 2
- 10 kDa heat shock protein, mitochondrial
Sequence:
MSLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLKMLVDGAGNIKLTKDGKVLLTEMQIQSPTAVLIARAAAAQDEITGDGTTTVVCLVGELLRQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKISKTNLSNDREFLLQVARSSLLTKVDADLTEVLTPIVTDAVLSVYDAQADNLDLHMVEIMQMQHLSPKDTTFIKGLVLDHGGRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKKIIDLKNEVCGMDPDKGFVIINQKGIDPMSLDVFAKHNILALRRAKRRNMERLQLVTGGEAQNSVEDLSPQILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGSTHYALAQTKDAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRYVGVDLNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRSTLKETPQ
Protein: 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory complex subunit p110) (26S proteasome regulatory subunit RPN2) (Q9V3P6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome regulatory subunit 8
- 26S proteasome regulatory subunit 4
- GH11341p
- 26S proteasome non-ATPase regulatory subunit 2
- 26S proteasome non-ATPase regulatory subunit 14
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome regulatory complex subunit p50
- Probable 26S proteasome non-ATPase regulatory subunit 3
Sequence:
MSLTSAAGIISLLDEPMPDLKVFALKKLDNIVDEFWPEISESIEKIEMLHEDRSFPENKLAGMVASKVFYHLGSFEDALTYALGAGDLFDVNARNEYTETIIAKCIDFYIAQRVEFIENPKEASVVDERLEGIVNRMIQRCLDDNQFRQALGIALETRRMDTFKDAIMKSDDVRGMLAYAYNVTMSLIQNRGFRNEVLRCLVSLYRDLGVPDYVNMCQCLIFLEDPFAVAEMLDNLTRSSVETNNLMAYQIAFDLYESATQEFLGNVLQHLKNTAPIPTALPSTFKPQGTTSEDGAKSEGDKSKSDEDITEETPADDKVERTIDSLNEVEKLHQKNIEKLISILSGEVSIDLQLQFLIRSNHADLQVLRGTKEAVRVSICHTATVIANAFMHSGTTSDQFLRDNLDWLARATNWAKLTATASLGVIHRGHEKDSLALMQSYLPKEAGPSSGYSEGGALYALGLIHANHGANIIDYLLQQLKDAQNENVRHGGCLGLGLAGMGTHRQDLYEQLKFNLYQDDAVTGEAAGIAMGMVMLGSKNAQAIEDMVSYAQETQHEKILRGLAVGISLTMFSRLEEADPLVTSLSSDKDPVLRRSGMYTIAMAYNGTGSNKAIRKLLHVAVSDVNDDVRRAAVTAIGFILFRSPEQCPSVVSLLAESYNPHVRYGAAMALGIACAGTGLREAIALLEPMVKFDPVNFVRQGALIASAMILIQHTDQSCPKSTFFRQLYAEVISNKHEDVMAKYGAILAQGIIDAGGRNATLSLQSRTGHTNLQAVVGMLAFTQYWYWFPLAHTLSLAFTPTCVIGLNSDLKMPKMEYKSAAKPSLYAYPAPLEEKKSEEREKVATAVLSIAARQKRRENADKKEDEKMDVDEDSKEGAAVKKDEEAKADEKMVTDEKPKKKDEKEKKKEEDKEKEAAGTSSEKDKDKEKDKKEKKEPEPTSEILQNPARVLRQQLKVLSVIDGQSYEPLKDVTIGGIIVFQHTGKAEDQELVEPVAAFGPMNDEEKEPEPPEPFEYIED
Protein: Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta-1-BP-1) (Transforming growth factor beta-1-masking protein large subunit) (Q00918)
Organism: Rattus norvegicus (Rat)
Function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (By similarity). Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q14766}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q14766}.
Interaction partners:
- Transforming growth factor beta-1 proprotein
- Transforming growth factor beta-2 proprotein
- Transforming growth factor beta-3 proprotein
- Fibrillin-1
- ADAMTS-like protein 2
- Latent-transforming growth factor beta-binding protein 2
- Integrin alpha-V
- Latent-transforming growth factor beta-binding protein 3
Sequence:
MAGAWLRWGLLLWAGLLAWSAHGRVRRITYVVRPGPGLPAGTLPLAGPPRTFNVALDARYSRSSTATSSRSLAGPPAERTRRTSQPGGAALPGLRSPLPPEPARPGAPSRQLHSKAGAQTAVTRFAKHGRQVVRSKVQQDTQSSGGSRLQVQQKQQLQGINVCGGQCCHGWSKAPGSQRCTKPSCVPPCQNGGMCLRPQFCVCKPGTKGKACEITAAQDTMSPVFGGQNPGSSWVPPEPAAKRTSTKKADTLPRVSPVAQMTLTLKPKPSMGLSQQIHSQVAPLSSQNVMIRHGQTQEYVLKPKYFPAPKVVSGEQSTEGSFSLRYGQEQGTAPFQVSNHTGRIKVVFTPSICKVTCTKGNCHNSCQKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVLGASMPKLYQHAQQPGKALGSHVIHSTHTLPLTMTNQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPVGQRVKEVQPGQSQVSYQGLPVQKTQTVHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKQSYHGYTQMMECLQGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCSCKMGFGPDPTFSSCVPDPPMISEEKGPCYRLVSPGRQCMHPLSVHLTKQICCCSVGKAWGPQCEKCPLPGTAAFKEICPGGMGYTVSGIHRRRPIHQHIGKEAVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTSSREHGPGVAEPEVVTAPPEKEIPSLDQEKTRLEPGQPQLSPGVSTIHLHPQFPVVVEKTSPPVPVEVAPEGSTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYKFSEQQRKCIDIDECAQAQHLCSQGRCENTEGSFLCICPAGFIASEEGSNCIDVDECLRPDVCRDGRCINTAGAFRCEYCDSGYRMSRRGHCEDIDECLTPSTCPEEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGSYMCSCHKGYSPTPDHRHCQDIDECQQGNLCMNGQCKNTDGSFRCTCGQGYQLSAAKDQCEDIDECEHRHLCSHGQCRNTEGSFQCLCNQGYRASVLGDHCEDINECLEDSSVCQGGDCINTAGSYDCTCPDGLQLNDNKGCQDINECAQPGLCAPHGECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRATEDSGVDRQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVQGTAEFSEMCPRGKGFVPAGESSYETGGENYKDADECLLFGEEICKNGYCLNTQPGYECYCKEGTYYDPVKLQCFDMDECQDPNSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCVQPTESNEQIEETDVYQDLCWEHLSEEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPMKDSDDYAQLCNIPVTGRRRPYGRDALVDFSEQYGPETDPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSYKCVCLPGYVPSDKPNYCTPLNTALNLDKDSDLE
Protein: RNA pseudouridine synthase 2, chloroplastic (EC 5.4.99.-) (RNA pseudouridylate synthase 2) (RNA-uridine isomerase 2) (Q3ECD0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Protein Iojap-related
- Pseudouridine synthase family protein
- At4g38020 family protein)
- Short integuments 2, mitochondrial
- Large ribosomal subunit protein uL24c
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL43
Sequence:
MLSISQLPSFSLTTAKSLRYPSSPSSSLSIFFSFFPKVSNFVRASSGIPNLVACSPTEIIIPRVNNAGLRIEEIVDAAKGKIRLDSWISSRINGVSRARVQSSIRLGLVTVNGRVVDKVSHNVKSGDEVNCTISELQPLKAEAEDIPLDIVYEDKHVLVVNKPAHMVVHPAPGNPTGTLVNGILHHCSLPCVDYSNSEEDDDSDEETFSDDEEMTTSPSSYAASVRPGIVHRLDKGTTGLLVVAKDEHSHAHLAEQFKLHTIERVYVSLTTGVPSPPQGRIEIPIGRDSSNRIRMAAIPGGVRGGRARHAASRYKVIETFAGGGSALVEWRLETGRTHQIRAHAKYMGVPLLGDEVYGGTKSMALSLLQKRVSRSDQEEIIELISRMDRPCLHAIVLGFTHPCTGEIVKFSCPPPSDLAEIVGLLRRSGL
Protein: Probable protein phosphatase 2C 5 (AtPP2C05) (EC 3.1.3.16) (O80492)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable protein phosphatase 2C 79
- Probable protein phosphatase 2C 64
- Probable protein phosphatase 2C 46
- Probable protein phosphatase 2C 67
- Probable protein phosphatase 2C 48
- Probable protein phosphatase 2C 38
- Probable protein phosphatase 2C 68
- Probable protein phosphatase 2C 4
- Protein SMALL AUXIN UP-REGULATED RNA 9
Sequence:
MSVSKASRTQHSLVPLATLIGRELRSEKVEKPFVKYGQAALAKKGEDYFLIKTDCERVPGDPSSAFSVFGIFDGHNGNSAAIYTKEHLLENVVSAIPQGASRDEWLQALPRALVAGFVKTDIEFQQKGETSGTTVTFVIIDGWTITVASVGDSRCILDTQGGVVSLLTVDHRLEENVEERERITASGGEVGRLNVFGGNEVGPLRCWPGGLCLSRSIGDTDVGEFIVPIPHVKQVKLPDAGGRLIIASDGIWDILSSDVAAKACRGLSADLAAKLVVKEALRTKGLKDDTTCVVVDIVPSGHLSLAPAPMKKQNPFTSFLSRKNHMDTNNKNGNKLSAVGVVEELFEEGSAVLADRLGKDLLSNTETGLLKCAVCQIDESPSEDLSSNGGSIISSASKRWEGPFLCTICKKKKDAMEGKRPSKGSVTT