wanglab/gogpt-training-data huggingface dataset:
Protein: Fasciclin-1 (Fasciclin I) (FAS I) (FCN) (P10674)
Organism: Drosophila melanogaster (Fruit fly)
Function: Neural cell adhesion molecule.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
- Fasciclin-2
- Complex I-49kD
- Complex I-49kD
Sequence:
MLNAAALLLALLCAANAAAAADLADKLRDDSELSQFYSLLESNQIANSTLSLRSCTIFVPTNEAFQRYKSKTAHVLYHITTEAYTQKRLPNTVSSDMAGNPPLYITKNSNGDIFVNNARIIPSLSVETNSDGKRQIMHIIDEVLEPLTVKAGHSDTPNNPNALKFLKNAEEFNVDNIGVRTYRSQVTMAKKESVYDAAGQHTFLVPVDEGFKLSARSSLVDGKVIDGHVIPNTVIFTAAAQHDDPKASAAFEDLLKVTVSFFKQKNGKMYVKSNTIVGDAKHRVGVVLAEIVKANIPVSNGVVHLIHRPLMIIDTTVTQFLQSFKENAENGALRKFYEVIMDNGGAVLDDINSLTEVTILAPSNEAWNSSNINNVLRDRNKMRQILNMHIIKDRLNVDKIRQKNANLIAQVPTVNNNTFLYFNVRGEGSDTVITVEGGGVNATVIQADVAQTNGYVHIIDHVLGVPYTTVLGKLESDPMMSDTYKMGKFSHFNDQLNNTQRRFTYFVPRDKGWQKTELDYPSAHKKLFMADFSYHSKSILERHLAISDKEYTMKDLVKFSQESGSVILPTFRDSLSIRVEEEAGRYVIIWNYKKINVYRPDVECTNGIIHVIDYPLLEEKDVVVAGGSYLPESSICIILANLIMITVAKFLN
Protein: DIS3-like exonuclease 2 (EC 3.1.13.-) (Q8CI75)
Organism: Mus musculus (Mouse)
Function: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03045, ECO:0000269|PubMed:23594738}. Cytoplasm, P-body {ECO:0000255|HAMAP-Rule:MF_03045}.
Interaction partners:
- Exosome complex component 10
- Exosome complex component RRP40
- Exosome complex component RRP41
- Exosome complex component RRP45
- Exosome complex component CSL4
- Exosome complex component RRP43
- Exosome complex component RRP46
- Exosome RNA helicase MTR4
- Terminal uridylyltransferase 4
- Nuclear nucleic acid-binding protein C1D
Sequence:
MNHPDYKLNLRSPGTPRGVSSVVGPSAVGASPGDKKSKNKSMRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEDQWKAVKPESNDKEIEATYEADIPEEGCGHHPLQQSRKGWSGPDVIIEAQFDDSDSEDRHGNTSGLVDGVKKLSISTPDRGKEDSSTPVMKDENTPIPQDTRGLSEKSLQKSAKVVYILEKKHSRAATGILKLLADKNSDLFKKYALFSPSDHRVPRIYVPLKDCPQDFMTRPKDFANTLFICRIIDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPDEVGKRRDLRKDCIFTIDPSTARDLDDALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYDHAQSMIENPTEKIPEEELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKIFRTFPEQALLRRHPPPQTKMLSDLVEFCDQMGLPMDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSGMLQDQEQFRHYALNVPLYTHFTSPIRRFADVIVHRLLAAALGYSEQPDVEPDTLQKQADHCNDRRMASKRVQELSIGLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALALRSYSFQKVGKKPELTLVWEPDDLEEEPTQQVITIFSLVDVVLQAEATALKYSAILKRPGLEKASDEEPED
Protein: Bicoid mRNA stability factor (SD10676p) (Q95NR4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASILRTGKLLRYFAGFTRNVLVNSVRENETSNLLNNAPCMCGQFQNGFATNAAAKAELSLDKQIRRLDQDVRRIGRISRRDLEEVLDEIRSHRTATSSQSLLVIRCCGNLVPEELPEVRTALVQEIWKTLNALNVPMNISHYNALLRVYLENEHGFAPTDFLAEIEAKGIEPNRVTYQRLIARYCQQGDIEGATRILEFMRAKSLPVNENVFNSLILGHSQANDLESAKGILGVMKQAGLEPSADTYTTLLCAFARHGDLAAVKETLAECEQKEIILLDKDLLDIVYTLTVNGNGEHVDDVLTKLRLSPGFNQDAVNVILRLVNKGHEDVGLKLLRVMPRSSRVNGEPVDVGAFFIRQMVKANRPVEKILSICKSLQSEGLNPKALTIATEAGLTNGVINNALPLLQEMKNAGLPIRQHYFWPLICSAESNQVLEIVRRMQQEFSVFPNSETVRDYVIPNLKEKNWERIVTSLRDAGVPNSTAVTSAVYSALVTHQIAEAAKIMEKNRAYYVPFLFKQPLILALSHTNDYASFIRCVRQIHEGLQFRQGKDEEVEQVEGVAAVPTERITPDVVGAIVQEATTYFRRDRGATLEKILKGLVKQGLSISSDKATQLSEQLGSELTPKISELLGKLSSGELEPVPLPNSGKRSLDSLSINELERFIVNVEGKGENANNIKRQLLNACFRSQNLEKTLQVIEKLEAEKFQIPVGIYAQLIDLNTHHKKSSEALEIYGKLKAKDATFQLDNLKAVRLADLLLQEERVDAAFKILEENKKEVPVAEAEGSYNYMSTVWRILNSLAEAGQPERLRKLFDVLVGANYIVPTNVLLGPLIKVHLVKDDIPKAIEAFEEICQKYKSTPWKNELACRLIQKEDAANLQKLTDLSTGIHGEVNSLYDLVFSFVECGRVRQARKILETPGLRTRPQRINSACDRYKNEGLLQPLEGLIEATKDLGHIDRNKIYYTLLLSYDKADEAEKALGLWTKMQEENVTPNDAFLLKLAEILSKKNIDVPFVVPETQNEQAKAKKSKAKDATTTEAATETAKVAEQPKEKAAKKEPAKTETAKPPKTASHLSGFRKAIQANDPDAAISHKQSVLSGEKIGALDTSRLIELLVRADRLTEATKYVEELLGDKLHPQPKIFKFYLNKIAAAGDLETMQRIGQQLNDEQKRLISFDNRFCHANIVAGKAEEFLKHLTTEIDAAKTPEESTKLAEKFPRGGAVGILEKHPELVPQYQSLAEKFAAHNQLGPMNVLWMHLISTGQEAASKEIWDKHLSNAPRLMFQRVLQTAREQQDEKLASTVISQLKNSKISEGAIGNAYSCLIDIQTTKGNSDKAMVVLANAIKDVSLENINRTALLRLKQAVEEKSQKFPYTIPEKRTKADDSSSSSSSSSSDDDVSPSVPETVPPKPDSKA
Protein: C-type lectin domain-containing protein (Q9XX56)
Organism: Caenorhabditis elegans
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Seven TM Receptor
- Nematode cuticle collagen N-terminal domain-containing protein
- BTB and MATH domain-containing protein 36
- Protein TSSC4
- Nose resistant-to-fluoxetine protein N-terminal domain-containing protein
- Alpha-mannosidase
- C-type LECtin
- C-type lectin domain-containing protein
Sequence:
MLRLFIIVCLVCSVAPDCVPGDVGFGDSCYSFNRVHGKFKDANDLCVKMFGGSLVKITNIIDNNWMQKLAVNHLDADYNSFWIGASDAAHYTNWTWIDGSPMRFSNWGPGQPLEDRHCGTMLISTGKWFSQVCDERIQFLCQYPNGAYSPTCPPCLEI
Protein: Integration host factor subunit beta (IHF-beta) (A7MUP0)
Organism: Vibrio campbellii (strain ATCC BAA-1116)
Function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
Interaction partners:
Sequence:
MTKSELIERLCAEQTHLSAKEVEDAVKDILEHMASTLESGDRIEIRGFGSFSLHYREPRVGRNPKTGDKVELEGKYVPHFKPGKELRERVNLGS
Protein: Pre-mRNA-splicing factor cwf10 (114 kDa U5 small nuclear ribonucleoprotein component homolog) (Complexed with cdc5 protein 10) (O94316)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein G
- Pre-mRNA-splicing factor cwf19
- Small nuclear ribonucleoprotein-associated protein B
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43
- Small nuclear ribonucleoprotein Sm D1
- Pre-mRNA-splicing factor brr2
- Probable U2 small nuclear ribonucleoprotein B''
- Protein saf4
Sequence:
MMEEDLYDEFGNYIGPENEEDEEELFPQAPSPTIAQVPSFEEVIPDEELEDVERAEEMALSHLEPQNAVVLHEDKQYYPSAEEVYGSNVDIMVQEQDTQPLSQPIIEPIRHKRIAIETTNVPDTVYKKEFLFGLLTGTDDVRSFIVAGHLHHGKSALLDLLVYYTHPDTKPPKRRSLRYTDTHYLERERVMSIKSTPLTLAVSDMKGKTFAFQCIDTPGHVDFVDEVAAPMAISDGVVLVVDVIEGVMINTTRIIKHAILHDMPIVLVLNKVDRLILELRLPPNDAYHKLRHVIDEVNDNICQISKDLKYRVSPELGNVCFASCDLGYCFTLSSFAKLYIDRHGGIDVDLFSKRLWGDIYFDSKTRKFAKQSLDGSGVRSFVHFILEPLYKLHTLTISDEAEKLKKHLSSFQIYLKPKDYLLDPKPLLQLICASFFGFPVGFVNAVTRHIPSPRENAARKASQSYIGPINSSIGKAILEMSREESAPLVMHVTKLYNTVDANNFYAFARVYSGQVKKGQKVKVLGENYSLEDEEDMVVAHIAEICVPCARYRLHVDGAVAGMLVLLGGVDNSISKTATIVSDNLKDDPYIFRPIAHMSESVFKVAVEPHNPSELPKLLDGLRKTNKSYPLSITKVEESGEHTIFGTGEMYMDCLLYDLRTLYSEIEIRVSDPVARFCETAVDTSSIKCFSDTPNKKNRITMVVEPLEKGISNDIENGKVNINWPQKRISEFFQKNYDWDLLASRSIWAFGPDDRGTNILRDDTLSTDVDKNVLNSVKEYIKQGFQWGTREGPLCDETIRNVNFRLMDVVLAPEQIYRGGGQIIPTARRVCYSSFLTASPRLMEPVYMVEVHAPADSLPIIYDLLTRRRGHVLQDIPRPGSPLYLVRALIPVIDSCGFETDLRVHTQGQAMCQMVFDHWQVVPGDPLDKSIKPKPLEPARGSDLARDFLIKTRRRKGLVEDVSTTRYFDQEMIDSLKEAGVVLSL
Protein: Chromosome 19 open reading frame 47 (J3QS16)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVSVTMATSEWIQFFKEAGIPPGPAVNYAVMFVDNRIQKSMLLDLNKEIMNELGVTVVGDIIAILKHAKVVHRQDMCKAATESVPCSPSPLAGEIRRGTSAASRMITNSLNHDSPPSTPPRRPDTSTSKISVTVSNKMAAKSAKAT
Protein: Abcissic acid stress ripening (A0A1Z3GD05)
Organism: Hordeum vulgare (Barley)
Interaction partners:
Sequence:
MAEEKHHHHLFHHKKEGEDFQPAADGGADVYGYSTETVVTGTGNEGEYERITKEEKHHKHKEHLGEMGAVAAGAFALYEKHEAKKDPEHAHKHKIEEELAAAAAVGAGGFVFHEHHEKKQDHKEAKEASGEKKHHLFG
Protein: ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23) (Q93YS4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Protein DETOXIFICATION 50
- Protein NRT1/ PTR FAMILY 4.6
Sequence:
MSMEKPPLASGLARTRSEQLYETVAADIRSPHGSMDANGVPATAPAAVGGGGTLSRKSSRRLMGMSPGRSSGAGTHIRKSRSAQLKLELEEVSSGAALSRASSASLGLSFSFTGFAMPPEEISDSKPFSDDEMIPEDIEAGKKKPKFQAEPTLPIFLKFRDVTYKVVIKKLTSSVEKEILTGISGSVNPGEVLALMGPSGSGKTTLLSLLAGRISQSSTGGSVTYNDKPYSKYLKSKIGFVTQDDVLFPHLTVKETLTYAARLRLPKTLTREQKKQRALDVIQELGLERCQDTMIGGAFVRGVSGGERKRVSIGNEIIINPSLLLLDEPTSGLDSTTALRTILMLHDIAEAGKTVITTIHQPSSRLFHRFDKLILLGRGSLLYFGKSSEALDYFSSIGCSPLIAMNPAEFLLDLANGNINDISVPSELDDRVQVGNSGRETQTGKPSPAAVHEYLVEAYETRVAEQEKKKLLDPVPLDEEAKAKSTRLKRQWGTCWWEQYCILFCRGLKERRHEYFSWLRVTQVLSTAVILGLLWWQSDIRTPMGLQDQAGLLFFIAVFWGFFPVFTAIFAFPQERAMLNKERAADMYRLSAYFLARTTSDLPLDFILPSLFLLVVYFMTGLRISPYPFFLSMLTVFLCIIAAQGLGLAIGAILMDLKKATTLASVTVMTFMLAGGFFVKKVPVFISWIRYLSFNYHTYKLLLKVQYQDFAVSINGMRIDNGLTEVAALVVMIFGYRLLAYLSLRQMKIVT
Protein: Glutathione S-transferase D7 (EC 2.5.1.18) (Q9VG93)
Organism: Drosophila melanogaster (Fruit fly)
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May be involved in detoxification.
Interaction partners:
- Glutathione S-transferase D1
- Glutathione S transferase D10, isoform A
- Glutathione S transferase D8
- Glutathione S-transferase D4
- Glutathione S-transferase D2
- Glutathione S-transferase D5
- Bifunctional glutamate/proline--tRNA ligase
- Glutathione S transferase D9, isoform A
- Glutathione S transferase O1
- Glutathione S-transferase S1
Sequence:
MPNLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVIWESRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRTGKFGDQEALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTVEWFSFDLSKFPNVERWLKNAPKVTPGWEQNLESLQQGKKFLQDLQAAKEKEVKA
Protein: Striatin 4 (F1M6V8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Striatin-3
- Striatin-interacting protein 1
- Striatin
- Programmed cell death protein 10
- CTTNBP2 N-terminal like
- Serine/threonine-protein kinase 25
- Suppressor of IKBKE 1
- Serine/threonine-protein kinase 24
- Cortactin-binding protein 2
- MOB-like protein phocein
Sequence:
MMEERAAAAVASAASCRPLGSGTAPNPTAAAPASSPAPGPGPVGKGGGGGGSPGPTAGPEPLSLPGILHFIQHEWARFEAEKARWEAERAELQAQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKKADLSEQVSNGPVESVTLDNSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGRSLELNGAGEPVEGAPRASPGPGGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLEQIPFLQNCEDEDSDEDDELDSVQHKKQRVRLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGEGSPDPRRCASEGNPHELESRRVKLQGILADLRDVDGLPPKVTVPPPGTPQPRPHEGSFGFSSDVFIMDTIGGGEVSLGDLADLTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSCVLEGHGDAVWGLAFSPTSQRLASCSADGTIRIWDPSSSGSSCLCTFPMAGEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGGALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAKVFV
Protein: Cytochrome c oxidase assembly factor 5 (Q99M07)
Organism: Mus musculus (Mouse)
Function: Involved in an early step of the mitochondrial complex IV assembly process.
Interaction partners:
- Protein PET117 homolog
- Cytochrome c oxidase copper chaperone
- Large ribosomal subunit protein mL51
- Cytochrome c oxidase assembly factor 6 homolog
- Cytochrome c oxidase assembly protein COX19
- FAD-linked sulfhydryl oxidase ALR
- Complex I assembly factor ACAD9, mitochondrial
Sequence:
MPRYYEDKPEGGACAGVKEDLGACLLQSACVLQEGKSPRQCLKEGNCRALQYSFFECKRSMLDARSRFRGRKGY
Protein: tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit trm82 (Transfer RNA methyltransferase 82) (O74863)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03056}.
Interaction partners:
- tRNA
- tRNA
- tRNA
- tRNA
- Multifunctional methyltransferase subunit trm112
- tRNA
- tRNA
- tRNA pseudouridine synthase 4
- 18S rRNA
- tRNA
Sequence:
MSEQRVFKHPCQFLTWNSKHNYIVCCSGPYLLGFSCSTGEKIFEHCYRDNINEKHREAAAYGEAIRQVAFSKDYSRMATVSEDKCLRLWDSTQPDKIELLYQKNIPKRCADLCFAGSNEIVFGDKFGDVYCVDENWFTTSEVTEEKKSNVVEGKQEPVNNDTLKDSKLQKLEPIMGHVSILTQLIVAQNPQNSKEEIIITSDKDEHIRISRFPNAFVIEGFCLGHEDFVSRMSLYDNRTLISGGGDNHVFVWDLENFKCLDAFDLRSAFSTYLSLNQPMVVSVILPIFKRQLVAFACEGMAGLIFAKVTPEKRLLFHSALKLSGPVLDAVLLDTDTDQILISLDSSFTFGACFECVKFDEGNAAVLTKPDVIKRIESDGLISTEKPFCPLAQIHTLRKNHSKFIRSVETGTSSPSVESKDN
Protein: Mitochondrial carrier protein CoAc2 (Mitochondrial carrier family protein 1) (Mitochondrial coenzyme A transporter CoAc2) (ZmCoAc2) (B4F8I5)
Organism: Zea mays (Maize)
Function: Required for the accumulation of coenzyme A in the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:23590975}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDARAREAAETSGPGLPLAVRELLAGGVAGGVAKTAVAPLERVKILFQTRRAEFHGSGLIGSFRTIYRTEGLLGFYRGNGASVARIVPYAALHYMAYEEYRRWIILGFPNVEQGPVLDLVAGSIAGGTAVICTYPLDLVRTKLAYQVKGAVSVGFRESKPSEQVYKGIMDCVKTIYRQNGLKGIYRGMAPSLYGIFPYSGLKFYFYEKMKSHVPEEHRKGIIAKLGCGSVAGLLGQTITYPLDVVRRQMQVQALSSSSLVGRGTFESLVMIAKQQGWRQLFSGLSINYLKVVPSVAIGFTVYDSMKVCLKVPSREETAVAVLAEERSNTAPIPSS
Protein: PelD (Q9HZE7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- PelC
- PelF
- PelE
- PelG
- PelA
- PelB
- diguanylate cyclase
- Transcriptional regulator FleQ
- Mannuronan synthase
- FimX
Sequence:
MSAHKDFTLAPRASGSVSWVETLVISALALGLGWWFSPDDPLQVNATFPWVILAPLLLGMRYGFVRGLASAALLVAALFAFRARGVEAYAQVPAAFIVGVLLCAMLVGEFRDIWERRLERLELANEYRQLRLDEFTRAHHILRISHDRLEQRVAGNDQSLRSSLLGLRQLLRELPGDEAPLDALAETVLALLAQYGSLRIAGLYRVRYDRTPEPQPLATLGEMPALDADDLLVRTCLERGELVSVRQELLERGEQRAHSALQVCVPLVDTDGRILALLAVEQMPFFVFNERTFSLLAILAGHIADLLQSDRRALQLADIDAQRFSQYLKRSLLDARDHGLPACLYAFELTDARYGEEVQRLLEGSQRGLDVQLRLRNDEGRRVLLVLLPLTSAEGSQGYLQRLRILFAERFGQARELESLGVRIRQYELDAGNDRQALGHFLFNECGLNDQQVAI
Protein: Uncharacterized protein (Q57Y01)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSAGSEPITPPVFNEEAARGDEGVRRLTVEKSGEDPSTATKDVVNTRLHRRSSSGHRVSVLTDDTNASSGAASRAMHPTRKKSSGNVNFLNNVVDFLCTLYGRDVVDKDEQQEPQPGPDASIKEGVQNTPLLPDVLTPQTPCLAVGGDIPVVNERHHLAQRQHPHTHYGFISDRPRILSAVPMGRSVSEDRLQFIVEQILDGYRRINDKSRATPQGRHSLKDACNNVSVFVNHAVDNLVVREASFSLAETRSNQSILSTAYDGCFQTPLTFRTFSEIGEMDEESEVLIKPDFHAVLPTFERRLPDSCVSVSAPIRMRDDQPIPEDATINELEIDSTPLGLRRRQRSTNSRAFVSFLPSPREREVGTSGWSEMNMSLQSNGVDSLATTGSWETAATGVNSLTDTAAQGRSEPDGEIARFISREEIERCVLVSVEGRFRTHINSLKKHELLLSPPEAEKIAATRRSVLSAVNASTTSPMVQNIIEFFSN
Protein: Transcriptional regulator PINT87aa (A0A455ZAR2)
Organism: Homo sapiens (Human)
Function: Enhances the binding of the PAF1 complex to target gene promoters and plays a role in negative regulation of transcription. May function as an anchor to keep the PAF1 complex on target gene promoters, sequentially pausing RNA polymerase II-induced mRNA elongation. Inhibits FOXM1-mediated transcription of PHB2.
Subcellular location: Nucleus {ECO:0000269|PubMed:30367041}.
Interaction partners:
Sequence:
MLWLPDRGSCSARSPSGMLRGAPGGWRYGRRCGRRRQSCCCCCCCSHVGAPLSFHREASLVSHDGHDIMKQHCGEESIRGAHGYKNK
Protein: Zinc finger matrin-type protein 4 (Q9H898)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MKSSDIDQDLFTDSYCKVCSAQLISESQRVAHYESRKHASKVRLYYMLHPRDGGCPAKRLRSENGSDADMVDKNKCCTLCNMSFTSAVVADSHYQGKIHAKRLKLLLGEKTPLKTTATPLSPLKPPRMDTAPVVASPYQRRDSDRYCGLCAAWFNNPLMAQQHYDGKKHKKNAARVALLEQLGTTLDMGELRGLRRNYRCTICSVSLNSIEQYHAHLKGSKHQTNLKNK
Protein: Wtf element wtf14 (O74512)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May act in meiotic drive.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000255, ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000255, ECO:0000269|PubMed:16823372}. Note=Localizes to the endoplasmic reticulum in both vegetative cells and in spores. {ECO:0000250|UniProtKB:A0A482ASA5}.
Interaction partners:
- Wtf element wtf11
- Meiotic drive suppressor wtf18
- Meiotic drive suppressor wtf9
- Meiotic driver wtf4
- Meiotic drive suppressor wtf21
- Meiotic drive suppressor wtf25
- Meiotic driver wtf19
- Meiotic driver wtf23
Sequence:
MENNHHLAKDSLDELNPKRGKGEHETQVSQYTVVEEATIPQSLVKTSRPADHKVMEASKVADTRTAWSTKIPAVLLPVFVINIALFKYLVFANFSTKDRVLFGLGNGGINIFSMWLLLATYETWFRSIKEVIVACGAGIRSFPQKRGVNMLYAILKLTFVNAFAIPLLMFFRSHFEQWRLGCPLVERVIGVMLNVAYFIIEIENPGLFTRVFNKYCDCLFAIRDILNRN
Protein: Alpha-amylase AMY3 (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) (P08117)
Organism: Triticum aestivum (Wheat)
Function: Important for breakdown of endosperm starch during germination.
Interaction partners:
- Polyamine transporter PUT1
- Polyamine transporter PUT1
- Amino acid permease/ SLC12A domain-containing protein
- Polyamine transporter PUT1
- Polyamine transporter PUT1
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- Amino acid permease/ SLC12A domain-containing protein
- Polyamine transporter PUT1
- WEB family protein
Sequence:
MGKHSATLCGLLVVVLCLASSLAQAQILFQGFNWESWKTQGGWYKFMQGKVEEIASTGATHVWLPPPSQSVSPEGYLPGQLYNLNSKYGSGADLKSLIQAFRGKNISCVADIVINHRCADKKDGRGVYCIFEGGTSDNRLDWGPDEICSDDTKYSNGRGHRDTGGGFDAAPDIDHLNPRVQRELSAWLNWLKTDLGFDGWRLDFAKGYSAAMAKIYVDNSKPAFVVGELYDRDRQLLANWVRGVGGPATAFDFPTKGVLQEAVQGDLGRMRGSDGKAPGMIGWMPEKTVTFIDNHDTGSTQRLWPFPSDKVMQGYAYILTHPGIPCIFYDHVFDWKLKQEITALATVRSRNGIHPGSTLDILKAEGDLYVAKIGGKVITKIGSRYNIGDNVIPSGFKIAAKGNNYCVWEKSGL
Protein: Small ribosomal subunit protein eS8A (40S ribosomal protein S8-A) (RP19) (S14) (YS9) (P0CX39)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS12A
- Small ribosomal subunit protein uS13A
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS4B
- Small ribosomal subunit protein eS12
- Ribosome biogenesis protein BMS1
- Small ribosomal subunit protein eS24A
- Protein BFR2
- Small ribosomal subunit protein eS25B
Sequence:
MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKKNVKEEETVAKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK
Protein: Trafficking protein particle complex subunit 14 (Microtubule-associated protein 11) (Q8WVR3)
Organism: Homo sapiens (Human)
Function: Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether. TRAPP II complex has also GEF activity toward RAB1A (By similarity). TRAPPC14 is dispensable for TRAPPII complex integrity but mediates RAB3IP preciliary vesicle trafficking to the mother centriole during ciliogenesis. Modulates YAP1 activity as transcriptional regulator.
Subcellular location: Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:30715179}. Vesicle {ECO:0000269|PubMed:30715179, ECO:0000269|PubMed:31467083}. Midbody {ECO:0000269|PubMed:30715179}. Cytoplasm {ECO:0000269|PubMed:31467083}. Note=During mitosis, precedes alpha-tubulin in gap formation of cell abscission at the midbody and is co-localized with PLK1 at the edges of microtubules extensions of daughter cells post cytokinesis abscission (PubMed:30715179). Colocalizes with RAB3IP on preciliary vesicles (PubMed:31467083). {ECO:0000269|PubMed:30715179, ECO:0000269|PubMed:31467083}.
Interaction partners:
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit 1
- Trafficking protein particle complex subunit 2
- Trafficking protein particle complex subunit 2-like protein
- Trafficking protein particle complex subunit 12
- Trafficking protein particle complex subunit 4
- Trafficking protein particle complex subunit 10
- Trafficking protein particle complex subunit 8
- Calcium-binding and spermatid-specific protein 1
- Trafficking protein particle complex subunit 9
Sequence:
MESQCDYSMYFPAVPLPPRAELAGDPGRYRALPRRNHLYLGETVRFLLVLRCRGGAGSGTGGGPGLGSRGAWAELATALAALASVSAGGGMPGGGGAGDQDSEPPGGGDPGGGGLFRGCSPLLTHGPGPATSGGATTLPVEEPIVSTDEVIFPLTVSLDRLPPGTPKAKIVVTVWKREIEAPEVRDQGYLRLLQTRSPGETFRGEQSAFKAQVSTLLTLLPPPVLRCRQFTVAGKHLTVLKVLNSSSQEEISIWDIRILPNFNASYLPVMPDGSVLLVDNVCHQSGEVSMGSFCRLPGTSGCFPCPLNALEEHNFLFQLRGGEQPPPGAKEGLEVPLIAVVQWSTPKLPFTQSIYTHYRLPSVRLDRPCFVMTASCKSPVRTYERFTVTYTLLNNLQDFLAVRLVWTPEHAQAGKQLCEEERRAMQAALDSVVCHTPLNNLGFSRKGSALTFSVAFQALRTGLFELSQHMKLKLQFTASVSHPPPEARPLSRKSSPSSPAVRDLVERHQASLGRSQSFSHQQPSRSHLMRSGSVMERRAITPPVASPVGRPLYLPPDKAVLSLDKIAKRECKVLVVEPVK
Protein: Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (Aging-associated gene 10 protein) (HCV NS2 trans-regulated protein) (NS2TP) (Q9Y6H1)
Organism: Homo sapiens (Human)
Function: Transcription factor. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen).
Subcellular location: Nucleus {ECO:0000269|PubMed:23303788}. Mitochondrion {ECO:0000269|PubMed:25662902}. Mitochondrion intermembrane space {ECO:0000269|PubMed:25662902}. Note=Mainly localized in the intermembrane space. {ECO:0000269|PubMed:25662902}.
Interaction partners:
- Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial
- MICOS complex subunit MIC25
- ATP synthase peripheral stalk subunit d, mitochondrial
- Mitochondrial intermembrane space import and assembly protein 40
- F-box only protein 7
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
- 85/88 kDa calcium-independent phospholipase A2
- Cytochrome c oxidase subunit 6A1, mitochondrial
- Parkinson disease protein 7
- Vacuolar protein sorting-associated protein 35
Sequence:
MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMATTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQFLECAQNQGDIKLCEGFNEVLKQCRLANGLA
Protein: Transcriptional adapter (F4JFM6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR025024}.
Interaction partners:
Sequence:
MGRSKLASRPAEEDLNPGKSKRKKISLGPENAAASISTGIEAGNERKPGLYCCNYCDKDLSGLVRFKCAVCMDFDLCVECFSVGVELNRHKNSHPYRVMVSFQRRADNLSFSLVTSDWNADEEILLLEAIATYGFGNWKEVADHVGSKTTTECIKHFNSAYMQSPCFPLPDLSHTIGKSKDELLAMSKDSAVKTEIPAFVRLSPKEELPVSAEIKHEASGKVNEIDPPLSALAGVKKKGNVPQAKDIIKLEAAKQQSDRSVGEKKLRLPGEKVPLVTELYGYNLKREEFEIEHDNDAEQLLADMEFKDSDTDAEREQKLQVLRIYSKRLDERKRRKEFVLERNLLYPDQYEMSLSAEERKIYKSCKVFARFQSKEEHKELIKKVIEEHQILRRIEDLQEARTAGCRTTSDANRFIEEKRKKEAEESMLLRLNHGAPGSIAGKTLKSPRGLPRNLHPFGSDSLPKVTPPRIYSGLDTWDVDGLLGADLLSETEKKMCNETRILPVHYLKMLDILTREIKKGQIKKKSDAYSFFKVEPSKVDRVYDMLVHKGIGDST