wanglab/gogpt-training-data huggingface dataset:
Protein: LD29489p (Uncharacterized protein, isoform A) (Q9VI54)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- LD24704p
- Septin-interacting protein 1
- Pre-mRNA-processing-splicing factor 8
Sequence:
MSLFRKPKKIQRRVFSSNADEEEDGASLDPDAEMEAPPPPIISGKREKEKSRKAIKPQEDNSKPKALLSFADDEDDGEVFQVRKSSHSKKVMRMLDKERRKKKREERAENSGHPGGENGSTQHLESSGGPSSGPPNSNSNPANAGRYKSASDQSKSKKSDNHMIQTEIRTDDFVLVVKKSETPEAILNGRAALCAGREDMSDEEDQQSEDGGHDKTRHRFSKPEHLKQMLESGSIPDAAMIHAARKRRQRAREQGAGDYIPIEEPKEPAKLSNRLPCEDVEGDQSDDEERMDMNDITGRKEREERREQFYAVENDSTDGDSDREMNEWENQQIRKGVTAAQLVHSQHETVLSRFMIKPAPSGIGTGMDDGDSTAAQSTSTLLEQAYAKNALERTNLAAAVRSSVKTKKEKAKATALRTPQEILAAIQSRLSELKERSADHSASMARISTELKALKLQQLECQQNAPTAAAKYKFYQEIKCYVNDLVDCLSEKAPVIYDLEKRALQQYGKNQRYLVNRRRQDVRDQAKEIAESAKPITAASRRTPDYEEQVRRAAEREGRRTRRRCERERNDLLSSHLDGMSSDDEIADQQQELSVTTMAQIESQSVDALEDVTDDFSKIELILMKFFAWRKTDMSSYQDAFVSLCLPKVLAPLVRHELVLWSPLLDVYADIENMRWYQACMLYASQADETVEQLKIDPDINLVPALIEKIVLPKVTALVTECWDPLSTTQTLRLVGFINRLGREFPLSGTNKQLNKLFESIMERMRLALENDVFIPIFPKQVQEAKTSFFQRQFCSGLKLFRNFLSWQGILADKLLRELAIGALLNRYLLLAMRVCTPNDAINKAYIIVNTLPTVWLLPNSETLKNMELFIGYIKQTLENCDASNPIFMQSSDKAKQILQRLHSL
Protein: Probable gamma-secretase subunit PEN-2 (Q9FY84)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Gamma-secretase subunit APH1-like
- Nicastrin
- Presenilin-like protein At2g29900
- Presenilin-like protein At1g08700
- Putative RNA-binding protein family protein)
- At1g71480 family protein)
- Vacuolar protein sorting-associated 9A-like protein
- Protein ASPARTIC PROTEASE IN GUARD CELL 2
- Protein CLT3, chloroplastic
- tRNA-splicing endonuclease subunit Sen2-1
Sequence:
MEATRSDDPSLNPIRNRNPNPNPNPNPLSTIISSAQVWPTIDGPLGLTEEASVDYARRFYKFGFALLPWLWFVNCFYFWPVLRHSRAFPQIRNYVVRSAIGFSVFTALLSAWALTFSIGGEQLFGPLYDKLVMYNVADRLGLSGLA
Protein: tRNA wybutosine-synthesizing protein 4 (tRNA-yW synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase) (O60157)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).
Interaction partners:
- tRNA wybutosine-synthesizing protein 3
- tRNA wybutosine-synthesizing protein 2
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
- tRNA
- tRNA
- tRNA
- Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit
Sequence:
MSNKNQRKTKSKDREVRKTNDSSILSKASVEKCGYPGFTVGHSYYQPFIQKSPRRSPSVNRGYWTRCMAIRFAVYQFLKNKTGKRKAIVNLGAGYDPLAFQLLSSHEYNTDDVVFYDVDYPETIENRVQMIRSDSFLSSIVLEDKEFDLDGTEIHTKNYHSFGCNLNLLNQLESCLEKYGIDYCNDAILFISEVAAVYMPRQASEKLIRWMSKFPDAHSCFFEQIAPATFDHPFANVMVKHFKEWGTPLHGLYAYPTIESLKSRWVKNGWEYVEILDVCTFWNFLMDSKLKHLCEMVEPFDEWEEFYFFLQHYSIQHASSKLVGKYDLVESPDPCMQYIRYVKSEIIFNNSPLTLRNSIYSLKRTDLPACLKELPSLRLPAVCDLDDSVIVQGGLSTAGRSKDAYLISEKDDGSIMKITTDSLTSCMGQSVVSIDKKTCMFIGGRESPKKILSSCIYFADGNWSDFPSLPYASHRASSVSIKHNGSSYVVLLAGKPFGGCLIWSDSKRKWNTLKCKDPLFYSRWGACLHWSSKLKKGILCGGMNELNEPVREVLEWEMVLRDDDHFEIVTRVLNFDVQVEILLSRIGSKVVFFGDDSKPIIVGGAAVFRTILWEEESVCINMNDYSVTGVCIEETEKRPVFTMFGISGMGNHLQIFGGGCICFSFGSCLNENATFYKLVSA
Protein: DNA-directed RNA polymerase subunit (EC 2.7.7.6) (D5G8D7)
Organism: Tuber melanosporum (strain Mel28) (Perigord black truffle)
Interaction partners:
- 
- 
- DNA-directed RNA polymerase
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerase subunit
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase
- 
- DNA-directed RNA polymerase
- 
Sequence:
MNISNPVSSEVTGVNFTFLCKDDITKLSVKQVVNPATFETVIPGNVPVPVVGGLYDPALGASDALRQRCLTCHLDYKYCPGHVGHISLPVPVYHPLFFDQMLKMLRSSCLYCFHFRMARAEVNRFECKLKLIQYGLLVEAAELDDIHPNTRGEEEGEEGEFSGSTEMEAFYAKREKFVARAIRRHLRSGGLDEGKVMSVAEERRKVVKEFLSTIQFPRKCNRCQAISPGFRKDGYSKIFEVPLTPKAQSQNVQYGFQRPNAAMMQKKPNRLPETKNHDLNRKGAAGRLLHSMEVLNNLSRLFEKEREILQLLYQPREAISKTPKPLTPEMFFIHAIAVPPTKFRPPQAAGGEISESATNKQLVKILQGCLAIRDYNDKFNNPEIEAGAKTVIISKLMQAFVTLQDDVNSFLDSSKSPLTGAAARTLEEGIKQKLEKKEGLFRMNMMGKRVNFAARSVISPDPNIETREIGVPPVFASKLTYPEPVTEINHQWLMRLRIHLSKTLLTPDALSLSDSKSKRVHRHLLNGDVVLMNRTYDPYALRQL
Protein: Probable receptor-like protein kinase At2g23200 (EC 2.7.11.-) (O22187)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- S-protein homolog 10
- S-protein homolog 11
- Plant intracellular Ras-group-related LRR protein 1
- Disease resistance protein SUMM2
- Cyclase-associated protein 1
Sequence:
MENFCFQDSVSLFITIMVLVLLPRLSLSDTSTYTRPENFYVNCGSDSNVFYGGQTFVGDTNSSTNSVSFTNKGTEVINDQSSVAPEIYRTVRIFRHPSSYKFKLDSLGLHFVRLHFSVVFSRADLLTARFTVSATSGSNHHLKSFSPQNLTNTPRVEEFLLMMNSLEFEIRFVPDHSSLALINAIEVFSAPDDLEIPSASDKNLHTIYRLNVGGEKITPDNDTLGRTWLPDDDDFLYRKDSARNINSTQTPNYVGGLSSATDSTAPDFVYKTAKAMNRSSNEQVGMLMNVTWSFKVKSNHRHFIRIHFSDILSNLSNSDSDFYLFVNGYWRVDVKPSEQPRLASPFFKDVVNVSDGSGLLNISIGTKEANKDAGFLNGLEMMEVLSKSGSDYSNRSSSRVHIITGCAVAAAAASALVFSLLFMVFLKRRRSKKTKPEVEGTVWSPLPLHRGGSSDNRPISQYHNSPLRNLHLGLTIPFTDILSATNNFDEQLLIGKGGFGYVYKAILPDGTKAAIKRGKTGSGQGILEFQTEIQVLSRIRHRHLVSLTGYCEENSEMILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSGSEGAIIHRDVKSTNILLDEHNIAKVADFGLSKIHNQDESNISINIKGTFGYLDPEYLQTHKLTEKSDVYAFGVVLLEVLFARPAIDPYLPHEEVNLSEWVMFCKSKGTIDEILDPSLIGQIETNSLKKFMEIAEKCLKEYGDERPSMRDVIWDLEYVLQLQMMTNRREAHEEDSTAINSGGSLVAPRLMVSDSFSTNSIFQNGDESKNRFGFTDSSETRVFSQLKISDAR
Protein: Cyclopropane mycolic acid synthase MmaA2 (CMAS) (EC 2.1.1.79) (Cyclopropane-fatty-acyl-phospholipid synthase) (CFA synthase) (Mycolic acid methyltransferase) (MA-MT) (S-adenosylmethionine-dependent methyltransferase) (AdoMet-MT) (SAM-MT) (Q7U1J9)
Organism: Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Function: Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. MmaA2 also catalyzes the biosynthesis of the cis-cyclopropanated methoxymycolates. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence (By similarity).
Interaction partners:
Sequence:
MVNDLTPHFEDVQAHYDLSDDFFRLFLDPTQTYSCAHFEREDMTLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGLTLSKNQAAHVQKSFDEMDTPLDRRVLLAGWEQFNEPVDRIVSIGAFEHFGHDRHADFFARAHKILPPDGVLLLHTITGLTRQQMVDHGLPLTLWLARFLKFIATEIFPGGQPPTIEMVEEQSAKTGFTLTRRQSLQPHYARTLDLWAEALQEHKSEAIAIQSEEVYERYMKYLTGCAKLFRVGYIDVNQFTLAK
Protein: PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a) (XAP135) (Q8WUB8)
Organism: Homo sapiens (Human)
Function: Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- AT-rich interactive domain-containing protein 2
- Bromodomain-containing protein 7
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
- Actin-like protein 6A
- SWI/SNF complex subunit SMARCC2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
- Protein polybromo-1
- SWI/SNF complex subunit SMARCC1
Sequence:
MAAAAGPGAALSPRPCDSDPATPGAQSPKDDNEDNSNDGTQPSKRRRMGSGDSSRSCETSSQDLGFSYYPAENLIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYLRELNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYSQMQQQNTQKVEASKVPEYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHVIQVPQGKYKVLPTERTKVSSYPVALIPGQFQEYYKRYSPDELRYLPLNTALYEPPLDPELPALDSDGDSDDGEDGRGDEKRKNKGTSDSSSGNVSEGESPPDSQEDSFQGRQKSKDKAATPRKDGPKRSVLSKSVPGYKPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQCMECKTCIICGQPHHEEEMMFCDMCDRGYHTFCVGLGAIPSGRWICDCCQRAPPTPRKVGRRGKNSKEG
Protein: mRNA-decapping enzyme-like protein (EC 3.-.-.-) (DCP1 homolog) (Q9SJF3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: As a component of the decapping complex, involved in the degradation of mRNAs. Essential for postembryonic development.
Subcellular location: Cytoplasm, P-body {ECO:0000269|PubMed:17158604, ECO:0000269|PubMed:17485080, ECO:0000269|PubMed:19855049, ECO:0000269|PubMed:26133670}.
Interaction partners:
- D-aminoacyl-tRNA deacylase
- mRNA-decapping enzyme subunit 2
- Enhancer of mRNA-decapping protein 4
- Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic
- Protein decapping 5
- DEAD-box ATP-dependent RNA helicase 12
- DEAD-box ATP-dependent RNA helicase 6
- Sm-like protein LSM4
- Regulator of nonsense transcripts 1 homolog
- DEAD-box ATP-dependent RNA helicase 8
Sequence:
MSQNGKIIPNLDQNSTRLLNLTVLQRIDPYIEEILITAAHVTFYEFNIELSQWSRKDVEGSLFVVKRSTQPRFQFIVMNRRNTDNLVENLLGDFEYEVQGPYLLYRNASQEVNGIWFYNKRECEEVATLFNRILSAYSKVNQKPKASSSKSEFEELEAKPTMAVMDGPLEPSSTARDAPDDPAFVNFFSSTMNLGNTASGSASGPYQSSAIPHQPHQPHQPTIAPPVAAAAPPQIQSPPPLQSSSPLMTLFDNNPEVISSNSNIHTDLVTPSFFGPPRMMAQPHLIPGVSMPTAPPLNPNNASHQQRSYGTPVLQPFPPPTPPPSLAPAPTGPVISRDKVKEALLSLLQEDEFIDKITRTLQNALQQ
Protein: NADPH-dependent alkenal/one oxidoreductase, chloroplastic (AtAOR) (EC 1.3.1.-) (Q9ZUC1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Reduces the double bond in short-chain unsaturated carbonyls. Acts preferentially on alpha,beta-unsaturated ketones rather on alpha,beta-unsaturated aldehydes. Has no activity with (E)-2-hexenal and (E)-2-pentenal. Contributes to detoxify stromal reactive carbonyls produced under oxidative stress.
Subcellular location: Plastid, chloroplast {ECO:0000305|PubMed:21169366}.
Interaction partners:
- NADP-dependent alkenal double bond reductase P2
- NADPH-dependent aldehyde reductase 1, chloroplastic
- NADPH-dependent oxidoreductase 2-alkenal reductase
- Quinone oxidoreductase-like protein
- Rhodanese-like domain-containing protein 11, chloroplastic
Sequence:
MNAALATTTATTPVLRRETPLLHYCSLTTKSPVYQINRVRFGSCVQTVSKKFLKISASSQSASAAVNVTADASIPKEMKAWVYSDYGGVDVLKLESNIVVPEIKEDQVLIKVVAAALNPVDAKRRQGKFKATDSPLPTVPGYDVAGVVVKVGSAVKDLKEGDEVYANVSEKALEGPKQFGSLAEYTAVEEKLLALKPKNIDFAQAAGLPLAIETADEGLVRTEFSAGKSILVLNGAGGVGSLVIQLAKHVYGASKVAATASTEKLELVRSLGADLAIDYTKENIEDLPDKYDVVFDAIGMCDKAVKVIKEGGKVVALTGAVTPPGFRFVVTSNGDVLKKLNPYIESGKVKPVVDPKGPFPFSRVADAFSYLETNHATGKVVVYPIP
Protein: NAC domain-containing protein 26 (ONAC026) (OsNAC26) (A2WQE4)
Organism: Oryza sativa subsp. indica (Rice)
Function: Transcription factor that acts redundantly with NAC20 to regulate the expression of genes involved in the biosynthesis of starch and storage proteins in grain. Directly binds to the promoters of starch synthase 1 (SS1), pullulanase (PUL), glutelin A1 (GLUA1), glutelins B4 and B5 (GLUB4 and GLUB5), alpha-globulin and 16 kDa prolamin, and activates their expression (By similarity). Possesses transactivation activity in yeast.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353, ECO:0000269|PubMed:27872632, ECO:0000269|PubMed:32989010}.
Interaction partners:
Sequence:
MGEQQQQVERQPDLPPGFRFHPTDEEIITFYLAPKVVDSRGFCVAAIGEVDLNKCEPWDLPGKAKMNGEKEWYFYCQKDRKYPTGMRTNRATEAGYWKATGKDKEIFRNHHMLIGMKKTLVFYKGRAPKGDKTNWVMHEYRLADASPPQPPPPPSSAEPPRQDDWAVCRIFHKSSGIKKPVQVPMQMPMQMQMPVAHQVPAANYQQQMAMASASIIQVPMQMQMPSMSDQLQMLDDFSTGSLMAPPPPPPSYSTLPGFPLQINGGAQQFVGNPSMYYQQQQQQQQQQMDMAAGGFVVSEPSSLVVSPQDAADQNNAADISSVACNMDATIWKY
Protein: BMP-like protein unc-129 (Uncoordinated protein 129) (G5EBY8)
Organism: Caenorhabditis elegans
Function: Required for the migration of axonal growth-cones and distal tip cells (DTC) along the dorsal-ventral axis of the body wall. Acts cell nonautonomously and independently of the classical daf-4, sma-6 or daf-1 TGFbeta receptor signaling. During axon migration, facilitates long-range repulsive guidance of unc-6/netrin by enhancing unc-5-unc-40 signaling at the expense of unc-5 alone signaling, probably through direct interaction with receptor unc-5. Involved in cell-cell contact formation in sensory rays in the developing male tail, via a pathway involving plx-2 and mab-20/semaphorin-2A.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:19169249}.
Interaction partners:
- Cell surface receptor daf-4
- Serine/threonine-protein kinase receptor sma-6
- Netrin unc-6
- Netrin receptor unc-40
- Cell surface receptor daf-1
- TGF-beta family profile domain-containing protein
- Netrin receptor unc-5
- Mothers against decapentaplegic homolog
- Dauer larva development regulatory growth factor daf-7
- Forkhead box protein unc-130
Sequence:
MRRLPIVLLLSVFSIANCAKVDVDLINETIRDLLHFKSSDPNVTSFHRSSHTLTEHMKNLYENFIDEDSNEDGNLVRAIEPAVGKFEGQEVLVFDVEGFDSHESIMRAELHFYLRRRDSFARRRSRQIRAKSVCVNEYCRQQTLKKIRVGGDENLEEYKVIWDATKSVFDSYHLDAKQAVFRITREHSKMRPYAEMIRKSTPFLVIYSKVNHTLDTVSVMKQTEQTKRKRRDLGNEELREYYNYNSIPLDNDDREPIKRKNGKKNSLSEEISSEDVWQGFGEETSREERERIANEELANDVRVVLLQNKNRCHKEGVLVSLKHFGWDRYVIEPKTIETSFCKGKCAKPMLTSGKASNHAMLQSLFAAEPVCCAPTNLKSLNFWYRDEKGRTVIRNYSKMLIGSCSCL
Protein: Protein disulfide isomerase-like 1-1 (OsPDIL1-1) (EC 5.3.4.1) (Endosperm storage protein 2) (Protein ESP2) (Q53LQ0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable protein disulfide isomerase that plays an essential role in the segregation of proglutelin and prolamin polypeptides within the ER lumen of endosperm. Required to retain proglutelin in the cisternal ER lumen until ER export and, thereby, indirectly prevents heterotypic interactions with prolamin polypeptides.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000269|PubMed:20627947}. Note=Distributed asymmetrically within the cortical endoplasmic reticulum (ER) and largely restricted to the cisternal ER. {ECO:0000269|PubMed:20627947}.
Interaction partners:
- Endoplasmic oxidoreductin 1, putative, expressed
- Protein disulfide isomerase-like 2-3
- Probable 5'-adenylylsulfate reductase 1, chloroplastic
- Nitrate reductase
- Nitrate reductase 1
- Nitrate reductase
- Heat shock 70 kDa protein BIP1
- Calnexin
- Heat shock 70 kDa protein BIP4
- Heat shock 70 kDa protein BIP2
Sequence:
MAISKAWISLLLALAVVLSAPAARAEEAAAAEEGGDAAAEAVLTLDADGFDEAVAKHPFMVVEFYAPWCGHCKKLAPEYEKAAQELSKHDPPIVLAKVDANDEKNKPLATKYEIQGFPTLKIFRNQGKNIQEYKGPREAEGIVEYLKKQVGPASKEIKSPEDATNLIDDKKIYIVGIFSELSGTEYTNFIEVAEKLRSDYDFGHTLHANHLPRGDAAVERPLVRLFKPFDELVVDSKDFDVTALEKFIDASSTPKVVTFDKNPDNHPYLLKFFQSSAAKAMLFLNFSTGPFESFKSVYYGAAEEFKDKEIKFLIGDIEASQGAFQYFGLREDQVPLIIIQDGESKKFLKAHVEPDQIVSWLKEYFDGKLSPFRKSEPIPEVNDEPVKVVVADNVHDFVFKSGKNVLVEFYAPWCGHCKKLAPILDEAATTLKSDKDVVIAKMDATANDVPSEFDVQGYPTLYFVTPSGKMVPYESGRTADEIVDFIKKNKETAGQAKEKAESAPAEPLKDEL
Protein: DAB adaptor protein 1 (A0A075B6G7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSTETELQVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGVPTSQKKEGVYDVPKSQPVSNGYSFEDFEERFAAATPNRNLPTDFDEIFEATKAVTQLELFGDMSTPPDITSPPTPATPGDAFIPSSSQTLPASADVFSSVPFGTAAVPSGYVAMGAVLPSFWGQQPLVQQQMVMGA
Protein: Zinc finger AN1 and C2H2 domain-containing stress-associated protein 13 (AtSAP13) (Q9SCM4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in environmental stress response.
Interaction partners:
- Zinc finger A20 and AN1 domain-containing stress-associated protein 5
- Zinc finger A20 and AN1 domain-containing stress-associated protein 9
- Zinc finger A20 and AN1 domain-containing stress-associated protein 10
- Single-strand DNA endonuclease 1
- Immune-associated nucleotide-binding protein 1
- Cysteine proteinase inhibitor 2
Sequence:
MGTPEFPDLGKHCSVDYCKQIDFLPFTCDRCLQVYCLDHRSYMKHDCPKGNRGDVTVVICPLCAKGVRLNPDEDPNITWEKHVNTDCDPSNYEKAVKKKKCPVPRCRELLTFSNTIKCRDCSIDHCLKHRFGPDHSCSGPKKPESSFSFMGFLSTNTKEAPASSSSSSRWSSLFASAEASISRLGNDISQKLQFASGNDGNSEKTQERNGKQNCGKVTVDVCPKCSRGFRDPVDLLKHIDKDHRGTSKA
Protein: Appendage-associated protein (Q5SF95)
Organism: Anaplasma marginale (strain Florida)
Function: Associates with actin filament appendages that are formed in the inclusion appendages of the parasitophorous vacuole during infection of the host erythrocyte.
Subcellular location: Secreted {ECO:0000269|PubMed:15557651}.
Interaction partners:
Sequence:
MGCPVSRGGSPGCGRRIAEELRLAEDARLRLALLGRCIVKGSPAQVRKELRAELKAIDAEWRPVIARESLRKELDAIDAEWQHAITFWHISRAIIGSIELSKELDAIDAEWRPVIVRESLRKELKAIDAEWRPAIRLESAYRAIIGSIELSKELKAIDAETQHAVELRRALRTIEGRIELSRELKAIDAEWAPRIAQAKEIAQARESLRKELNDIDAEWAPKIAQAKEIAQAKAELAAATDALKRAADKLQALGKMGTTSTPGTDLIGVVTTAVTTTLAGTQPAPGTDLVGVATPSTALGQPAPSTALTSVAAEVATPSTALGV
Protein: Protein OPI10 (Overproducer of inositol protein 10) (Q08202)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in phospholipid biosynthesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Uncharacterized protein YJL144W
- Protein BTN2
- Heat shock protein 78
- Heat shock protein 42
Sequence:
MFAAIASGNPLQLSVEVPNSNGLQHTIVLSRTKPKLYSHITLFILPNVTFPQDYIATVYFKLSPQEEFKLFGYLSSEKPSAIFKVQIPSSKKDAGDTSDGLGEIDMDVDDGSGAADPFTDTNGSSSNNISELIIGISIEPREQGMMKLEEWKASMNAEAQKNNSLILSRPNLGIIRNITTAGQLAQVYPSLTQELAAKIVQHAYNYLSGFLDAQGNVPIKRFDTWWDKFRNRLANDGTFLDEVTKN
Protein: Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2) (Q7Z5L9)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Interferon regulatory factor 2
- Interferon regulatory factor 2-binding protein 1
- Transcription cofactor vestigial-like protein 4
- Nuclear receptor corepressor 1
- Probable E3 ubiquitin-protein ligase IRF2BPL
Sequence:
MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS
Protein: Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (Q8BJU9)
Organism: Mus musculus (Mouse)
Function: Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9UGC7}.
Interaction partners:
- Large ribosomal subunit protein bL20m
- Large ribosomal subunit protein mL62
- Methyltransferase HEMK2
- Ribosome-recycling factor, mitochondrial
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL49
- MTRF1L release factor glutamine methyltransferase
- Ribosome-releasing factor 2, mitochondrial
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS12m
Sequence:
MRSGFLSGARRLWARRAFSRTPPPSEELLARGGPLRAFLERRVGSEAGGLDAGYPQLAAAARLLSEKERELRDTESLLHDENEDLKKLAESEIALCQKQITELKHQIISLLVPSEEMDGSDLILEVTAGVGGQEAMLFTSEMFDMYQQYAAFKRWHFETLEYFPSELGGLRHASASVGGPEAYRHMKFEGGVHRVQRVPKTEKQGRIHTSTMTVAILPQPTEIKLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPTGIISECQQERSQLKNRELAMKKLRARLYSMHLEEETAKRYNARKIQVGTKGRSEKIRTYNFPQNRVTDHRINKSLHDLESFMQGDCLLDDMIQSLKDCSDYEALVEMISRRD
Protein: Uncharacterized protein (Q586F2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DUF1663 domain-containing protein
Sequence:
MVATEQSRRGQDPCGDVTDIRKPSSIEAAEPSDYSSSSGNRGEGGRESRGIWAFKRASLVSVPQTPKTHQASWSTSNREGRGGGNRHRVSWHQHLDPHPNTGASVDDGATFWKVPRKVSEDPEDNMSTTHSISTSVSDPVSPSAANVVVKSATAENICVGASTDGEMKAMPHSMLLDGEVWEYIYLRKSSELRDAFASDIGDVLGFPFSTPIEFTPTRTGILAHCTLLYPETMKTEELYERLSRDKFPAMRRLYQTAKREHMITSCSTMYTTNISDRPISPSPEDMDGRRGSMQMMSSATSTNHKPEEYCLSKREESRDATKEDATGMDTESQEIHYSRFTERSMSRISMVPADIREAGMSKSHVVTSRAASPRCAKCLDQSMSHISMVPADVREAGMSKSHVEPSRAASPRCAKCLDQSMSRISMVPADIREAGMSKSHVVTSRAASPRCAKCLDQSMSHISMVPADIREAGMSKSEVEPSLAASLKCGKCLDQSMSRISTLPADIREAGMSKSHVVTSRAASPRCAKCLDQSMSRPSTLPADIREAGMSKSHVVTSRAASPRCAKCLDQSMSRQSTLPADIREAGMSKSEVEPSLAASLKCGKCLDQSMSRISMMPADVREAGMSKSEVEPSLAASLKCGKCLGQSMSRISMMPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISMMPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISMMPAGVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISMMPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISMMPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSHISMVPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSHISMVPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISMMPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRSSTLPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISMMPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISTLPADIREAGMSKSHVVTSRAASPRCAKCLDQSMSHISMVPADVREAGMSKSEVEPSLAASLRCAKCLDQSMSRISTLPADIREAGMSKSHVVTSRAASPRCAKCLDQSMSRISMMPADVREAGMSKSHVVTSRAASPRCAKCLDQSMSRISTLPADIREAGMSKSHVVTSRAASPRCAKCLDQSMSHISMVPADVREAGMSKSEVEPS
Protein: 4-hydroxybenzoate octaprenyltransferase (EC 2.5.1.39) (4-HB polyprenyltransferase) (PHB octaprenyl transferase) (P0AGK1)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. Geranyldiphosphate (GPP), all-trans-farnesyldiphosphate (FPP) and all-trans-solanesyldiphosphate (SPP) are also accepted as side chain precursors.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01635, ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:4552989, ECO:0000269|PubMed:8155731}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01635}.
Interaction partners:
- Chorismate pyruvate-lyase
- 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
- Flavin prenyltransferase UbiX
- Octaprenyl diphosphate synthase
- 3-demethoxyubiquinol 3-hydroxylase
- Ubiquinone biosynthesis O-methyltransferase
- Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
- 2-octaprenylphenol hydroxylase
- 2-octaprenyl-6-methoxyphenol hydroxylase
- Glutaredoxin 4
Sequence:
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF