wanglab/gogpt-training-data huggingface dataset:
Protein: Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (Q9DCD6)
Organism: Mus musculus (Mouse)
Function: Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in autophagy: while LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. Also required for the local activation of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex, regulating ubiquitination and degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) that activates RAC1 and downstream signal transduction. Thereby, regulates different biological processes including the organization of the cytoskeleton, cell migration and proliferation. Involved in apoptosis.
Subcellular location: Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:14530254}. Endomembrane system {ECO:0000250|UniProtKB:P60517}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10899939}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P60517}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P60517}. Note=Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (PubMed:10899939). Also localizes to discrete punctae along the ciliary axoneme (PubMed:24089209). {ECO:0000269|PubMed:10899939, ECO:0000269|PubMed:14530254, ECO:0000269|PubMed:24089209}.
Interaction partners:
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
- Sequestosome-1
- Next to BRCA1 gene 1 protein
- FUN14 domain-containing protein 1
- Ubiquitin-like modifier-activating enzyme ATG7
- Calcium-binding and coiled-coil domain-containing protein 2
- Ubiquitin-like-conjugating enzyme ATG3
- Ubiquitin-like protein ATG12
- Phosphatidylinositol 3-kinase catalytic subunit type 3
Sequence:
MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
Protein: Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) (Q9EQ32)
Organism: Mus musculus (Mouse)
Function: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22187458}. Cell membrane {ECO:0000305|PubMed:22187458}; Peripheral membrane protein {ECO:0000305|PubMed:22187458}.
Interaction partners:
- Phosphatidylinositol 3-kinase regulatory subunit alpha
- Tyrosine-protein kinase SYK
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Phosphatidylinositol 3-kinase regulatory subunit gamma
- Phosphatidylinositol 3-kinase regulatory subunit beta
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- B-lymphocyte antigen CD19
Sequence:
MAASGWGRGCDILIFYSPDAEEWCQYLQDLFVSCRQVRSQKTQTYRLVPDASFSAQDLWVFRDARCVLVLLSAGLVGCFGQPGLLPMLQRACHPPQRVVRLLCGVQPGDEDFQAFFPDWAHWQEMTCDDEPETYLAAVRKAISEDSGCDSVTDTEPEDERELPFSKQTNLPPEISPGNLMVVQPDRIRCGAETTVYIIVRCKLDEKVSTEAEFSPEDSPSIRVEGTLENEYTVSVKAPDLSSGNVSLKVYSGDLVVCETTVSYYTDMEEIGNLLSSAANPVEFMCQAFKIVPYNTETLDKLLTESLKNNIPASGLHLFGINQLEEDDMMTNQRDEELPTLLHFAAKYGLKNLTALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKTHIKEELMQGEEADDVYESMAHLSTDLLMKCSLNPGCDDELYESMAAFAPAATEDLYVEMLQASAGNPVSGESFSRPTKDSMIRKFLEGNSVKPASWEREQHHPYGEELYHIVDEDETFSVDLANRPPVPVPRPEASAPGPPPPPDNEPYISKVFAEKSQERLGNFYVSSESIRKEPLVRPWRDRPPSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRESITRRRKEKPKSGKHTDLEITVPIRHSQHLPEKVEFGVYESGPRKSVLPARTELRRGDWKTDSMSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEIPEITRSRGPGPTQVDGAPVVTGTPVGTLERPPRVPPRAASQRPLTRESFHPPPPVPPRGR
Protein: GH07636p (Q961U1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNLIEMGDYEFRVFAVNSAGRSEPSLCTMPIKVCEVLGGKKPDWITRLQDKVAPFGKDYTLQCAASGKPSPTARWLRNGKEIQMNGGRMTCDSKDGVFRLHISNVQTGDDGDYTCEAMNSLGFVNTSGYLKIGSPPIINRCPSELKLPEGDNSKIKIFYSGDQPLTVILKKNNEVICDSNDDTHVKVNIFDDYVAIYIRNIVKSDGGPYQIEFTNESGSATGEFYVHITGMPSAPTGPMGISYINKNSCMLNWRPPSYDGGLKVSHYVIERKDVSSPHWITVSSTCKDTAFNVQGLIENQEYIFRVMAVNENGMGPPLEGLNPIRAKDPIDPPSPPGSPQITEIGGDFVHLEWEKPESDGGAHIQGYWIDKREVGSNTWQRVNATICAANQINCINLIEGRQYEFRIFAQNVAGLSTESSASQAVKIIDPQAASPPLIVKPLRDANCIQNHNAQFTCTINGVPKPTISWYKGAREISNGARYHMYSEGDNHFLNINDVFGEDADEYVCRAVNKAGAKSTRATLAIMTAPKLNVPPRFRDTAYFDKGENVVIKIPFTGFPKPRIHWVRDGENIESGGHYTVEVKERHAVLIIRDGSHLDSGPYRITAENELGSDTAIIQVQISDRPDPPRFPLIESIGTESLSLSWKAPVWDGCSDITNYYVERREHPLSSWIRVGNTRFTSMAVSGLTPGKEYDFRIFADNVYGRSDASDTSTLIKTKESVKKKPIERKWEIDANGRKLRGKADGPVKDYDSYVFDIYSKFVPQPVEISQQSVYDRYDILEEIGTGAFGVVHRCRERSTGNIFAAKFIPVSHSVEKDLIRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMTEAEVINYMRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKITTGTAEFAAPEIVNREPVGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESFKYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTGDHSAMKQEINRDRYLAYREKLRRKYEDFERFLLPIGRLSEYSSLRKLLMEKYKIHDAVFDRRQAAPRFVIRPSSQFCYEGQSVKFYCRCIAIATPTLTWSHNNIELRQSVKFMKRYVGDDYYFIINRVKLDDRGEYIIRAENHYGSREEVVFLNVQPLPKEQPRYRTESTPVRRREPLPYTFWQEESETAPSFTFLLRPRVMQARDTCKLLCCLSGKPVPNVRWYKDGRELSKYEYAMTHSDGVVTMEIIDCKPSDSGKYSCKATNCHGTDETDCVVIVEGEWVTPEQAQLAHNFLYSGDRKYIEQPIKPAPLPIVTSRQYTSSSVQNTSEPQGDKVNVSNSNSSGISNKKKYASNSLQAPGSPSRSRSATKELILPPDDSLMCKPEFTKPLHDLTIHDGEQLILTCYVKGDPEPQISWSKNGKSLSSSDILDLRYKNGIATLTINEVFPEDEGVITCTATNSVGAVETKCKLTIQPLDKNINKRKVNAGDNAPKIVSHLESRFVRDGDAVNLACRIIGAQHFDVVWLHNNKEIKPSKDFQYTNEANIYRLQIAEIFPEDGGTYTCEAFNDIGESFSTCTINVTVPGDETKQPSFVKFPTSVSVLEGEGTTFECEIDSELLNLVWLKDGKPIDETLPRYSFTKDGHRYSFAVAKCNMDDVGQYQAKAVSGKAESICAFSMNVHTAES
Protein: 60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (Heat shock protein 60) (Q803B0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- 10 kDa heat shock protein, mitochondrial
- Heat shock protein 9
- Immunoglobulin binding protein
- Tcp1 protein.
- Heat shock cognate 71 kDa protein
- Heat shock cognate 71 kDa protein
- Heat shock protein HSP 90-alpha 1
- Heat shock protein 105 kDa
- T-complex protein 1 subunit theta
- ATP-dependent Clp protease proteolytic subunit.
Sequence:
MLRLPSVMRQMRPVCRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDRYKNIGAKLVQDVANNTNEEAGDGTTTATVLARAVAKEGFDTISKGANPVEIRRGVMMAVEEVISELKKNSKPVTTPEEIAQVATISANGDTEVGNIISNAMKKVGRKGVITVKDGKTLHDELEIIEGMKFDRGYISPYFINTAKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANQHRKPLVIVAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLQDMAVSTGGTVFGDEAMGLALEDIQAHDFGKVGEVIVTKDDTMLLKGRGDASAIEKRVNEIAEQLESTNSDYEKEKLNERLAKLSDGVAVIKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVPGGGCALLRCIPALDNIKPANADQKIGIDIIRRSLRIPAMTIAKNAGVEGSLVVEKILQSSTEIGYDAMNGEYVNMVERGIIDPTKVVRTALLDAAGVASLLSTAEAVVTEIPKEEKEMPAGGMGGMGGMGGMGGMGF
Protein: Zinc finger E-box binding homeobox 2 (A0A1B0GV02)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQETSPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTMGPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSDSSLGRQLQLLSNQGNVTVILIIILGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
Protein: BTB/POZ domain-containing protein KCTD20 (Potassium channel tetramerization domain containing 20) (Q8CDD8)
Organism: Mus musculus (Mouse)
Function: Promotes the phosphorylation of AKT family members.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24156551}. Note=Colocalizes with BTBD10 in filamentous structures. {ECO:0000269|PubMed:24156551}.
Interaction partners:
Sequence:
MNVHQGSDGDWSLQPELSCLGDEALAATQEKEGSSLVSSGLHSVTYPLAARSEDLALDYASQPASLPHPHIMPLPEDNKGSCFQSGSKRSHEPFIVPERFGNSGLGFGGGAHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYVIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIIMHHPPQVDELDRLNAPLSQMAPNDFQD
Protein: Non-specific lipid-transfer protein (Q9M6B6)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MASSMYLKLACVVVLCMVVGAPLAQGAVTCGQVTSSLAPCINYLRGTGAGAIPPGCCSGIKSLNSAAQTTPDRQAACKCIKSAAAGIPGINFGLASGLPGKCGVNIPYKISPSTDCSSVK
Protein: E3 ubiquitin-protein ligase RNF168 (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168) (Q80XJ2)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03066}. Note=Localizes to double-strand breaks (DSBs) sites of DNA damage. {ECO:0000255|HAMAP-Rule:MF_03066}.
Interaction partners:
- TP53-binding protein 1
- Mediator of DNA damage checkpoint protein 1
- Ubiquitin-conjugating enzyme E2 N
- E3 ubiquitin-protein ligase RNF8
- Histone H2AX
- Breast cancer type 1 susceptibility protein homolog
- Partner and localizer of BRCA2
- DNA repair protein XRCC4
- DNA ligase 4
- BRCA1-A complex subunit RAP80
Sequence:
MAAPKTSIPSLAECQCGICMEILLEPVTLPCNHTLCNPCFQSTVEKANLCCPFCRRRVSSWTRYHTRRNSLVNTDLWEIIQKHYAKECKLRISGQESKEIIDECQPVRRLSEPGELRREYEEEISRVEAERQASKEEENKASEEYIQRLLAEEEEEEKRQREKRRSEMEEQLRGDEELARSLSTSINSNYERNTLASPLSSRKSDPVTNKSQKKNTSKQKTFGDIQKYLSPKLKPGTALACKAELEEDICKSKETDRSDTKSPVLQDTEIEKNIPTLSPQTCLETQEQGSESSAGIPGPQLCVGDTKESLEGKVETVSTSPDDLCIVNDDGPRATVFYSNEAAVNSSSKIENEEYSVTGVPQLTGGNRVPTESRVYHLLVEEEISDRENQESVFEEVMDPCFSAKRRKIFIESSSDQEETEVNFTQKLIDLEHMLFERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDQYQLRTPSPPDRLLNRQRKNSKDRNSLQQTNADHSKSPRNTKGDYWEPFKNTWKDSVNGTKMPTSTQDNCNVSKSAYTVQHRKSQRSIVQMFQR
Protein: Arabinogalactan O-methyltransferase 2 (EC 2.1.1.-) (Q9FYG0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9C7F9}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Beta-glucuronosyltransferase GlcAT14C
- Beta-glucuronosyltransferase GlcAT14B
- Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein
- Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein
- Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein
- At1g71070/F23N20_6
- Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein
Sequence:
MIQDKSKGAKQTLLERPWFLAVALAGLIGGAMLITSFIRATDNTLSLCSTAKNTAASIAKYTATPIQLQSIVHYATSHTVPQQSFEEISISLNVLKERLPCNFLVFGLGRDSLMWASLNPGGTTVFLEEDPEWIEAVLKDAPSLRAHHVQYRTHLSEAGRLLSTYKNEPMCLPAKAFPIRYNEKCPLALTSLPDEFYDTEWDLIMVDAPKGYFPEAPGRMAAIFSSAIMARNRKGDGTTHVFLHDVNRKVENAFANEFLCEKYKVNSVGRLWHFEIPNAANMTDQPGDRFC
Protein: phosphatidylinositol-4,5-bisphosphate 3-kinase (EC 2.7.1.153) (A0A8I6AKZ7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLHVAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLDCLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRLVTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNNCIFIVIHRGTTSQTIKVSADDTPDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFGIKIKDLPKGALLNLQIYCCKTPSLSSKASVETPGSESKGKAQLLYYVNLLLIDHRFLLRHGGYVLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGKAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSSLPESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKRADPTVLSNETIGIIFKHGDDLRQDMLILQILRIMESIWEAESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDCCVYFTILQGCLR
Protein: Thymine-DNA glycosylase (A0A096MK32)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MNIILKKKSHREAKRTTNYSLEQVQALYSFPFQQMMAEAPNMADVAGQQMPAEAPAQDPVPEAPKRRKRKTRAAEAQDPVEPKKPAASKKSGKSTKSKEKQEKITDTFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERSTDVQEVQYTFDLQLAQEDAKRTAVKEEKYDPGYEAAYGGACGENPCNGEPCGFASNGLTANSAELGGESAPSDVPNGQWMAQSFAEQIPSFNNCGTGEQEAGSHAGSHA
Protein: Putative transcription initiation factor TFIID 111 kDa subunit (TAFII-111) (TBP-associated factor 111 kDa) (Q09813)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription initiation factor TFIID subunit 7
- TATA-box-binding protein
- SAGA complex/transcription factor TFIID complex subunit Taf6
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 4
- SAGA complex/transcription factor TFIID complex subunit Taf9
- SAGA complex/transcription factor TFIID complex subunit Taf10
- Transcription initiation factor TFIID subunit 11
- Transcription initiation factor TFIID subunit 13
- SAGA complex/transcription factor TFIID complex subunit Taf12
Sequence:
MSFDGLIVENENTKSGYNDGNDLTDLFKQNGTDMSVINSLLGDTNNPGMNESPKILDSSFENSNPQDGPNYEDFDFMGSIHKEFGNNINEMDDMEDVSDDNLPEEEQAVNYTGDKDDEDFGKLLAKEMGEEAAGQVLSGVGFSIPSGLVPPSEPSKTVSSTTEELQNEAQIRESIVKTFFPTFERGVLLNFSELFKPKPVKLAPPKKKTPKVCVPGRLTLEVDTDYAIIFNSKKSLPLKRNVVSPISTHTKKRRRTANTSQRNDGLDLNTVFTTNDWEKNIIYDESDVNKTNQSSFFIDKSLVDIDFAFDENIFDGDTGTSKVVLNLNDPKLLLQPQLPKKEDSQRSFADTHQRNSLAWKFNISNDPAYEMLKQNHQSKVRNTLSQLAIEHAAFAEKLTFPYYKTRLSKRAVRSYHRPTMSFKPNAAIVFSPLIVRKRSKDKHKSERELIPTTKEITMGDTTHAILVEFSEEHPAVLSNAGMASRIVNYYRKKNEQDESRPKLEVGESHVLDVQDRSPFWNFGSVEPGEITPTLYNKMIRAPLFKHEVPPTDFILIRNSSSYGSKYYLKNINHMFVSGQTFPVTDVPGPHSRKVTTASKNRLKMLVFRLIRRSPNGGLFIRQLSKHFSDQNEMQIRQRLKEFMEYKKKGDGPGYWKLKSNEVVPDEAGTRSMVSPETVCLLESMQVGVRQLEDAGYGKTMDEINDDEDEEQPAEQLLAPWITTRNFINATQGKAMLTLFGEGDPTGIGEGYSFIRTSMKGGFKPAGETADDKPEPQTKNAHAYNVAKQQRAYEEEINRIWNAQKRGLSINNLEELAKKYGINSIHDDYVESNEETTREETPSSDKVLRIVRLYRDKNGNLERKQETIHDPIVIHAYLKKRREIDEQSTALDAVVPTGDEAIDRRNRRRLEQELAKSQKNWERRRARHAAKEGINLNGEGRKPTTRKCSNCGQVGHMKTNKICPLFGRPEGGLATMLDKN
Protein: Draculin-like 3 (Draculin-like, tandem duplicate 3) (A0A075BR52)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEIEDSENMKDTTEPCRTEHCDDTEGQRDHMEGNKEGETEAKKSVACFHCKKRFTCKAHLQVHMRVHNKKKQKDRKATAEKLHTCDKSGKSFAYKSSLKKHMINHSGEKKHTCDQCGKSFPFKVYLEQHMLIHTGETLHECDQCGKSFRSKGEVKIHMLIHTGEKPHKCDQCGKSFRSKGEVKIHMLIHTGEKPHECDQCGKSFRSKGEVKIHMLIHTRKKPHECDQCGKSFRSKGEVKQHMSIHTGLKPYKCEECGKFFAQKNNLQVHMKVHTGEKPYRCDQCGKCFPYKQSLKLHLEIHAKGNPYTCDECGKSFKTCLQFRSHMTLHPEYKPYKCDQCEKSYGREDHLQRHMKYHTGEKPHKCEHCGKSFQMRDLLRSHLMVHREVKPYTCDQCGKGFTLKKCYNEHMNIHTGERPYTCDQCGKGFPYEQSLNLHMRFHRGEKPFTCDQCGQSFSQKGAYNIHMKIHTGEKPYTCDQCGMSFRHGSSLKLHMTHHTGEKPFHCDQCDKCYSTALFLKNHMKTHNKDQIYSCLTCGKTFNLLGCLRMHEKRHTLVKPFMCFDCGKCYFTDTELKQHLSVHSNERPYMCSLCFKSFSRMDSLKKHEKTHNRKIQNHHHDEGEHDQTSLLKG
Protein: AAA-ATPase At1g43910 (EC 3.6.1.-) (Q9LP11)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Calcium-transporting ATPase 12, plasma membrane-type
- Probable LRR receptor-like serine/threonine-protein kinase At1g51820
- Calcium-transporting ATPase 8, plasma membrane-type
- Putative methylesterase 13, chloroplastic
- At4g00080
- Protein PHLOEM PROTEIN 2-LIKE A6
Sequence:
MATLYSQVPSVSAVFSLYTSFSAITMLFRTILNEIVPKRIREYIAMKAVDFFSSYFQSDFTFVIEQRWEFVENQTFRAAEVYLPTCLAGLSTGKLLVGSSNLKNPAAEPKLGIPVNTKIIDNFEGIHLEWTLHSVETKKYLPEKRYFHLTCKKEFREKIMTDYFTYLAKSAEKIMSHRENLKIYTYNQDRSKWESAIFEHHTTFETLAVEPDLKKTLIDDLDAFSKGKDFFKSVGRAWKRGYLLYGPPGTGKSSMVAAIANHMKYHIYDLQIQSVRDDGELREILTSTKNRSILLIEDIDCGADASRRRQSKKKEEDGGEDDGEPQKRKKKFEVGISLSGLLNFVDGLWSSCGEEKIIIFTTNHKEKLDPALLRPGRMDVHILMDNCTPFVFKKLVALYLKTDEHVLFDPIEKLILEVSSTPAEVTQQLMASKNADIALKGLAEFLENKKLKKGEDSSVEEEGEIEDAETKEAET
Protein: Vimentin (V9HWE1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus matrix {ECO:0000256|ARBA:ARBA00004109}.
Interaction partners:
Sequence:
MSTRSVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
Protein: Uncharacterized protein (Q389Q5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVTPLVKRDGVLVPINSICWLAKNVFNVRVPLYRRVISCELSAVDVPRGTAPVLECAIDKAVSMIRDASHKYLRQDYYAEFPLLGYGDIIFSTNGQATEWASLQETLLFLGVGRIIRPICFRLEDLIDAEKRGALGEPVKVGAASAIPCAWAGDMSRHESSGLFRKVVAGRVVDVLRGDVYVVHWADKSADDNGGATSHESINADTSNGAANGEAECGASPLPELVILDAVQCYSTSTDGGYAALRWAQKNLLFSQVEVCVHSLSPSEMEVANSTQLFSHDQLRCVRSTVRVTSFAREGDATEDVGCSLVRQGHGLVRQVVEAAVPRSSNFHDILRAASERCRTIFSRPVAPSGGARDWLLGGSPGPGGIERALESFLGQAWFEGPTLAALWKATMFAGNIFQSCESRPLRTHVERPMRTIWSITAPVRQNVTFEGTLKSLSLVQECIGVSSGSKASTHAGGLESVGMSGQDRSLFLRVEVDAIFTDETILQVVGREEERTLGTIVVAPPEEVVQGRKAQIRIKYDNSPSVALSGEAPALSVVQRKYWPGKYTPEKPTAADTSKMTRLVDRVFQTEVTVDLRLEDRENEMVFALDIFVEFQGQEKKLERRAVYLLSDTQEMVDNEEVSSSSDDDDEGDDSIPGGKNVTGTEGVVVSEGQSVVEEHAVDLEADSDRPEKDALSSEKIYHSKIDFYFKVDNSKRQTGDFTEELRKWSEGLAYRDVFCIPVGVATVNGDQGYVGDILVLMGNEMQGVDDRRGTRKSVLFELGAKWWVPAELSSEAPGHTWSMISSLVLKFFAKALAEITAREQQQRSILVAEWWRRLTNVYNEMVAKKATAQEMMDSRLPVGAGICGLRSAPRAGGTASSGPDGNHQEDIDEVFRVSAGKRDFWYLAEWEGGGSTGDTRVGSSEPRISPFPQLLDTFLPPRLPLFVVSIFPRQLFAAFHKHHRSLVNSKNSLTAKQASNLHVDSAFVRLPRPFLPNFFASNLERLPVSLRNTAGAFVESLMDGKVPRQRGTAEWSYCAHEGVLSSVLSLLFMLRPCEPTNGGAVNFDVYNLMGNDHKNLNSVNVPNIDCSAVLYRVYPRNCGQALDGQEPKDPVLFLGSFCSSTSEVFGSQESILPTDASAIKFVARALGVESLVSSSRGSLSFNGCLVSGDSSTDDGGVFSILEGGGKACYPMASLGVGNQPLTSGVPRLYLPLPWLAVLGPPLVTRDEFDASLQDHKPREETKRLYIAVSYVPMCFSPNKPYNPISYGRCKRSRIYQRVCERSRRGLGVKDYFSLLLRRRSPVSSEKGASGRFADGTLRVYGTVNEPQFLYYQSRKQLRFHLGVQWPSILENFTNEKDATQAESEAEEKLLQEVAEAAKHVIDKVAERTSILQRFGGGANSRCTPPTRVYLRFRLNFQSNERSARKLRVMVYPVSEGNGRSMCGAEMGRGPEPPEGAAASQEELNPYRMFHMGDNVLSRSPYCVLVVSYCKESAKYQYEWDAEYESTSQGNMTASYGVIE
Protein: Diacylglycerol kinase 3 (AtDGK3) (DAG kinase 3) (EC 2.7.1.107) (Diglyceride kinase 3) (DGK 3) (Q8VZG1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity).
Interaction partners:
- Sulfoquinovosyl transferase SQD2
- Choline/ethanolaminephosphotransferase 2
- Phospholipid:diacylglycerol acyltransferase 1
- Choline/ethanolaminephosphotransferase 1
- Putative phospholipid:diacylglycerol acyltransferase 2
- Triacylglycerol lipase SDP1L
- Triacylglycerol lipase SDP1
- Diacylglycerol O-acyltransferase 1
- 1-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic
- Diacylglycerol O-acyltransferase 3
Sequence:
MDSPVSKTDASKEKFVASRPSTADSKTMRGCGLANLAWVGVDKVELRQRLMMPEYLRLAMRDCIKRKDSSAIPDHLLLPGGAVADMAPHAPMVVFINPNSGGRHGPVLKERLQQLMSEEQVFDLTEVKPHEFVRYGLGCLEKVAAEGDECAKECRARLRIMVAGGDGTVGWVLGCLGELNKDGKSQIPPVGVIPLGTGNDLSRSFGWGGSFPFAWRSAVKRTLHRASMGPVARLDSWKILVSMPSGEVVDPPYSLKPAEENELDQGLDAGIDAPPLAKAYEGVFYNYLSIGMDAQVAYGFHHLRNTKPYLAQGPISNKIIYSSFGCSQGWFCTPCVNDPGLRGLRNIMKIHIKKVNCSQWEEIAVPKNVRSIVALNLHSYGSGSHPWGNLKPDYLEKRGFVEAHCDDGLIEIFGFKQGWHASFVMAELISAKHIAQAAAVRFELRGGDWRDAFLQMDGEPWKQPMSTEYSTFVEIKKVPYQSLMINNE