wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial import inner membrane translocase subunit TIM9 (Protein EMBRYO DEFECTIVE 2474) (Q9XGX9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Subcellular location: Mitochondrion intermembrane space {ECO:0000269|PubMed:14730085}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM10
- Mitochondrial intermembrane space import and assembly protein 40 homolog
- Mitochondrial import inner membrane translocase subunit TIM22-4
- Mitochondrial import inner membrane translocase subunit TIM22-1
- Mitochondrial import inner membrane translocase subunit TIM8
- Mitochondrial import inner membrane translocase subunit TIM13
- Outer envelope pore protein 16-3, chloroplastic/mitochondrial
- Import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein
- Mitochondrial import receptor subunit TOM40-1
- Mitochondrial import inner membrane translocase subunit TIM50
Sequence:
MDASMMAGLDGLPEEDKAKMASMIDQLQLRDSLRMYNSLVERCFVDCVDSFTRKSLQKQEETCVMRCAEKFLKHTMRVGMRFAELNQNAPTQD
Protein: SET-binding protein (SEB) (Q9Y6X0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:11231286}.
Interaction partners:
- Polycomb group protein ASXL1
- Nuclear pore complex protein Nup98-Nup96
- Bifunctional epoxide hydrolase 2
- U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
- Galactoside alpha-
- Splicing factor U2AF 35 kDa subunit
- Serine/arginine-rich splicing factor 2
- Protein SET
- Methylcytosine dioxygenase TET2
- PHD finger protein 6
Sequence:
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKKRQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEELITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSASLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLVSEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP
Protein: Matrin-3 (Q8K310)
Organism: Mus musculus (Mouse)
Function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs. May bind to specific miRNA hairpins.
Subcellular location: Nucleus matrix {ECO:0000255|PROSITE-ProRule:PRU00130}.
Interaction partners:
- TAR DNA-binding protein 43
- Non-POU domain-containing octamer-binding protein
- RNA-binding protein FUS
- Heterogeneous nuclear ribonucleoprotein A1
- Splicing factor, proline- and glutamine-rich
- Paraspeckle component 1
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoproteins A2/B1
- RNA-binding protein 14
- Heterogeneous nuclear ribonucleoproteins C1/C2
Sequence:
MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDTDQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDAQKTESPAEGKEQEEKSGEDGEKDTKDDQTEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVSSDGKKEPSDKAVKKDPSASATSKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQNDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET
Protein: Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] (Q10473)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates such as apomucin-, MUC5AC-, MUC1- and MUC2-derived peptides (By similarity).
Subcellular location: [Polypeptide N-acetylgalactosaminyltransferase 1]: Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]: Secreted {ECO:0000250}.
Interaction partners:
- Glucosaminyl
- alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
- Hexosyltransferase
- Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
- C1GALT1-specific chaperone 1
Sequence:
MRKFAYCKVVLATSLVWVLLDMFLLLYFSECNKCEEKKERGLPAGDVLELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIAFNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRSQQWLLRNVTLPEIF
Protein: Cytochrome P450 monooxygenase vrtK (EC 1.-.-.-) (Viridicatumtoxin synthesis protein K) (D7PHY9)
Organism: Penicillium aethiopicum
Function: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system. The first step of the pathway is the production of the malonamoyl-CoA starter unit for the polyketide synthase vrtA. The aldolase vrtJ may be involved in the synthesis of the malonamate substrate for malonamoyl-CoA synthetase vrtB. The polyketide synthase vrtA then may utilize the malonamoyl-CoA starter unit, followed by sequential condensation of eight malonyl-CoA units to form the polyketide backbone. The cyclization of the last ring could be mediated by the lactamase-like protein vrtG. The proposed post-PKS tailoring steps are an hydroxylation at C5 catalyzed the cytochrome P450 monooxygenase vrtE, a hydroxylation at C12a catalyzed by VrtH and/or VrtI, and an O-methylation by the O-methyltransferase vrtF. VrtC is then proposed to catalyze the transfer of a geranyl group synthesized by vrtD to the aromatic C ring of the tetracyclic polyketide intermediate of viridicatumtoxin to yield previridicatumtoxin. Finally, the cytochrome P450 monooxygenase vrtK catalyzes the spirocyclization of the geranyl moiety of previridicatumtoxin to afford viridicatumtoxin.
Interaction partners:
Sequence:
MAFSTYLGSLESSLVLKGLAGVWLVWYIGRVFYNIFLHPLANVPGPLLCKFSKIPWDYWQWTGRLPQNTAKVHAKYGEIVRIGPNELSFTNNAAWNDIFAKVPGRAQWPRHPKRVPQGKNGPQSIMNTAGTYHARFRRLLNHAFSEKGLQEQQDLITKYIDIFVSKVDGFARTGQSLDVTKWFVMVGFDVISDLGWSEPFNCVENGEVHEWMKTFAETAFDTQLKFLFRERGLMFLAPYLVPMKLQLARLNNFKYARARVEERIKTGGTRGDFWDKISVKSAGDNASGEGLTKEEMVVAAVTLVGTGSHTISTLLTGLAYFLGTNPHTMKKLVDEIRTSFNSPEEIDLVSVHKLKYLTACLNETMRLYPPVINMLWRTPPQGGGHASGIFIPEGTGCNMSFFGIAQNPDYFTRPLDFCPERFLPDPPAEFRDDNHEAYHPFSLGAYNCLGQNLANAESRLIMTKLLWYFDFELDGTVDKDWLDQKSYGVFIKKELPVKFHPGPNAVRHVANGNGVATNGHANGHANGHARINTK
Protein: Mitochondrial processing peptidase alpha subunit, putative (EC 3.4.24.64) (Q386B6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Reiske iron-sulfur protein, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- Mitochondrial processing peptide beta subunit, putative
- Mitochondrial processing peptidase, beta subunit, putative
- Electron transfer protein, putative
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase, mitochondrial, putative
- Acyl carrier protein
- NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial
- Cytochrome c
Sequence:
MYRRAVAAAIPAVTAKNARSISQYNFGQKPLTESWSPTGRSTPAAAGSAAQSAGIGEAKTTLLPNGTRIITQQRGGPVVSIGAYILAGPAYDPVGCPGLHHLMHTALTTSNYNNSLFQLDRSIRSTGASFSHFEKDKYYIGLRLDARVDMWKSNTSGATSDAKRFDLNLLQDTIFTAISAPRFHEPDLERFRDTIDNNLKELRWQRPAQYAIQQLETVAFYKEPLGNPRHVPEWSNGRITSKALLDQYARYVTPDRVVVAGVNMEHDELVAEYESNPYPHSSNAPHHAAFAKGLGKPAFDITNEHSQYSGGELHEHEDRPKEMCTKPDMDTETAIAVGYLAFGRSKTSLQRYVATLVYQQLFNIVIHDSLRYEQDVVLDGVRSFYLPYHSAGLVGFTAITSPENAVPLVKATMKGIQNVKFDNAALLEAAKHRAAVELTSQCWDSSRDICDYLGTSLSLDAKASNSTQYLNPSEVLAAVRNVTASELKEVKECMMGSKPSLFGHGEMLAFPSLRQLGA
Protein: Chemokine (C-X-C motif) ligand 8a (Interleukin-8 isoform X1) (A0A0G2KYH9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Chemokine
- C-X-C chemokine receptor type 2
- Chemokine
- Stromal cell-derived factor 1
- C-X-C motif chemokine 19 precursor
- Chemokine
- Chemokine
- Stromal cell-derived factor 1
- Nuclear factor NF-kappa-B p105 subunit isoform X1
- Transcription factor Jun
Sequence:
MTSKIISVCVIVFLAFLTIIEGMSLRGLAVDPRCRCIETESRRIGKHIKSVELFPPSPHCKDLEIIATLMTTGQEICLDPSAPWVKKIIDRIIVNRKP
Protein: Cleavage stimulation factor 50 kDa subunit (Q9V9V0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Cleavage stimulation factor 64 kD subunit
- Probable cleavage and polyadenylation specificity factor subunit 2
- Protein suppressor of forked
- Cleavage and polyadenylation specificity factor subunit 4
- Cleavage and polyadenylation specificity factor 73
- Cleavage and polyadenylation specificity factor subunit 1
- Symplekin
- Cleavage and polyadenylation specificity factor subunit 5
- YTH domain-containing protein 1
- Factor interacting with poly
Sequence:
MRDEILDPSNLVKNREILYRLMISQLMYDGLEKFAMELSMLVKADQCAPSERLLHVMIAGMQTLSDKDKTNSDDVLPGIDLEFEPEASALAPEPHSYETAYVTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERMLAKSAPEDIEPGREQQGHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSVKKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAIPSQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAHGGAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAGTTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLTLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRANNQ
Protein: Myc-associated zinc finger protein (MAZI) (Pur-1) (Purine-binding transcription factor) (Serum amyloid A-activating factor-1) (SAF-1) (Transcription factor Zif87) (ZF87) (Zinc finger protein 801) (P56270)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator, potentially with dual roles in transcription initiation and termination.
Subcellular location: Nucleus {ECO:0000305|PubMed:10727212}. Note=In brains of Alzheimer disease patients, present in a plaque-like structures.
Interaction partners:
- Kinesin-like protein KIF22
- RNA-binding protein EWS
- E3 ubiquitin-protein ligase TRAF7
- E3 ubiquitin-protein ligase RNF4
- Nucleosome-remodeling factor subunit BPTF
- Myc proto-oncogene protein
- Transcription factor Jun
Sequence:
MFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCGKMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVCPMAAAAAAAAAAAAAAVAAPPTAVGSLSGAEGVPVSSQPLPSQPW
Protein: Protein BCH1 (BUD7 and CHS6 homolog 1) (Q05029)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Member of the CHS5-ARF1P-binding proteins (CHAPS) which mediates export of specific cargo proteins, including chitin synthase CHS3.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16498409, ECO:0000269|PubMed:17000877}; Peripheral membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16498409, ECO:0000269|PubMed:17000877}. Note=Trans-Golgi network location requires interaction with CHS5 and with myristoylated GTP-bound ARF1 for the recruitment to the membranes.
Interaction partners:
- Chitin biosynthesis protein CHS5
- ADP-ribosylation factor 1
- Chitin biosynthesis protein CHS6
- Protein BCH2
- Bud site selection protein 7
- Chitin synthase 3
- [PSI+] induction protein 2
- SAGA complex/transcription factor TFIID complex subunit TAF9
Sequence:
MLSQTSIPEVKEDVIGYALHQRRARVGQFQDLGPPDLITLIKSLPSSSSTTTATASANDNGATSNINGQDPTTIVTELHSHDKLKGQIGTFFYCMGIDTSDPTSITIFAKKITDLFLDTPQIWFGKKKHFHVSKISISSWNAFRKYDVNIIVHIPGTVQTYIINSDGEQSQLPSVAEASSGRNSQDLNVNMIWAETFMSGIVRDIMIMKDNRADGESQNLVETLIFNPFTSGELEDVANNFIKLFPLVYEKGVYLDAPTHVLNPSLTNNYLVETLVEIVRLTKSLEACRKMLKKLIEIHPEAVIILIRVYFACDLEIDAVDLINEQLNSPSSFLADDSKTSHIQLIFKSELLSIQSEFLLDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDMSNALLSLNACPMSQVKEKYVLRRIAPITSDENLHLPLPLDASIEEISSLNPMDVQLEQKSADPNLVNLSASSLKSTFQLAYKLLTEIVQITGWEQLLKYRSKIFVMEDEYQGSTSSIDEAEVRGNDISKMRSKRLCERWLDNLFMLLYEDLKTYTDWQSEQLYFDAQNSKYHKLTVEWELFGLCAKRLGHLPEAAKAFQIGLSQRFSPVCAKNLLQFYIDEHKRIRRDSVSANSELTSSQILSSINDIDSSIIDLVVKICCWNHRWYIEFSIILIDALSVAVQDMGITKVHNEIASRFSDPVAQLIDDNILNFLKNFTNDTFDN
Protein: Transcription initiation factor TFIID subunit 9 (Q5BF86)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 12
- Transcriptional regulator Ngg1, putative
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 2
- TATA-box-binding protein
- Transcription initiation factor TFIID subunit 13
- Transcriptional adapter 2
- Transcription factor TFIID complex 145 kDa subunit, putative
Sequence:
MASPSQAAPSTQPLTPPAEPSSTNNATTTNTTAAPSQQPTQPTSAPTTTPAPASQPAQIPSTSLKDSGKSRRPRDVRLIHMLLAAQGVTAYQERVPLQLLDFAYRYTSGVLQDAVHLTTEGYAGTGADTTTSSGNKGPPEVNSVTLPALRLSIASRLHYQFQTGLPKEFLMDVAAERNRVALPGATRGFDAGAGKPAASNSVLMAGMRLPPERFCLTGTGWKMSDEWESEGEEDIAAPEEKNDVMAGAEREEGEGEGDEDEDGKMEDIFGEDAVMGDDDGDKDMTDV
Protein: Heat shock protein beta-1 (HspB1) (25 kDa IAP) (Actin polymerization inhibitor) (Heat shock 25 kDa protein) (HSP 25) (Heat shock 27 kDa protein) (HSP 27) (Q00649)
Organism: Gallus gallus (Chicken)
Function: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P04792}. Nucleus {ECO:0000250|UniProtKB:P04792}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P04792}.
Interaction partners:
- non-specific serine/threonine protein kinase
- Protein kinase domain-containing protein.
- non-specific serine/threonine protein kinase
- Heat shock cognate 71 kDa protein
- Cytochrome c
- BCL2 associated athanogene 3.
- Eukaryotic translation initiation factor 4 gamma 1.
- Polyadenylate-binding protein
- Heat shock protein beta-8
- Heat shock factor protein 3
Sequence:
MAERRVPFTFLTSPSWEPFRDWYHGSRLFDQSFGMPHIPEDWYKWPSGSAWPGYFRLLPSESALLPAPGSPYGRALSELSSGISEIRQSADSWKVTLDVNHFAPEELVVKTKDNIVEITGKHEEKQDEHGFISRCFTRKYTLPPGVEATAVRSSLSPDGMLTVEAPLPKPAIQSSEITIPVTVEAKKEEPAKK
Protein: AP-3 complex subunit beta (Q383L4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
- Mu-adaptin 3, putative
- AP-3 complex subunit delta
- AP complex subunit sigma
- AP-1 complex subunit gamma
- AP-4 complex subunit epsilon
- AP complex subunit sigma
- AP complex subunit sigma
- AP complex subunit beta
- Clathrin heavy chain
Sequence:
MNRAIIAEKASLASERAKEFISSGGSIVSRARSLVSGDAQFFAVQPKPEDLRRHLNSDCIHEKSVAMKRIIAQMCKGYDMSTFFADVVKNIHSPSVELRKLIYFFVTHYAEERPNEALLSISAFQKDLMDHSMHVRSLALRMLSAMRIPAIHTLVMVAVQKCALDTEPLVRKTAAISLAQVYAVNGSEADLETIYSILQQLLADKNSEVAAAAALSFVEICPHEVSFIHKVYRNLCRVIGDCDEWGQVVLIHVLLRYARTQFCDPNEQTGRRELISDSSDEAEQSKKNKENDKEEGVNDANDGESSSETTSSSSSSWDRKMLGLRRGGPNAAMLLDSDHRLLLDSVKPLLMSLNSAVVVAATAVICHCGPKADMDACTLPLLRLLAGPDERHSVVLSTIHTIVLTHAEPFVPYIREFFLMPQDKREIRILKLSIISKLATANNFPDLFREFRHYTRSYHVEHVVDAVRGLGLIAVRLSSVCTSQVMRVVLPLLSHKNAEVVSESIKVLQLLVVQGNSSGRQTARLVYRLLQRVIKGEVTSDSAKAVILWLVGENIQLHNVIAAAAPECFRILVKSFKTEGSEVRKQVLMLGCKIWMFLDGSGAVAERFRQLFFYLIELANFDDDYDVRDYARLVGCAVDRQSATFEGLKRMLLFREKKQPQSSDPYAEHTHYELGSLSHFIGKPFTGYHPLPPWATVPSDPLLRLPPGCEVRGDGADSGDDSMSDDGDDDDSSMMYSDNSSDSGTCRGSGSSDASTSVHSSYTGDDGYSSTDGSQQRGGNSTSDEMGRGDDEEQRTPAEEAVIRPSDASSKTNITNIAAEASDAPRRPVVKVTVRRLGAPKPAPDSKTVPTETEGGVAAAVTLEKEGSRSGGTPGASSTTAGNNAVREVINDKTTASVEGGSDRALDTPTREGSGPAE
Protein: Probable transcription factor At4g00390 (Storekeeper-like protein At4g00390) (O23063)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alpha/beta-Hydrolases superfamily protein
- Defensin-like protein 268
- F-box/FBD/LRR-repeat protein At1g13570
- Putative defensin-like protein 288
- ATG8-interacting protein 2
- Haloacid dehalogenase-like hydrolase family protein
- Reticulon-like protein B17
- Mitochondrial import inner membrane translocase subunit TIM50
- Spire, putative
- Grap2/cyclin-D-interacting protein
Sequence:
MTKKLDPPTAPSSDEDDVETSEDDSSSSEEDEPIKSLPATTAAAPAKSTAVSAATPAKSTSVSAAAPSKSTAVSAAADSDSGSESETDSDSESTDPPKSGSGKTIASKKKDDPSSSTATLALPAVKSGAKRAASEAATTSTKRVKKDEESVKKPALFQRLWSDDDEISMLQGMIDYHADTGKSPSADTNAFYEFQKKSISFEVSKSQFSDKVRSLRKKYRAKEGKDEPRFVKAHDKKAFELSKFIWGPKGIALDSNAKSNGVSKKSASKTKEKLDSVKQDLAFVGVSSTNGDDWFEKSSLARMIAGSGIDEYYVRQKWSSFTLETKKIVEEKFQLMQAKELEAMLDKSVRLTDLTSYFVDASKN
Protein: Ubiquitin-like domain-containing protein (Q57ZT8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHVLGRDPTSNCLPNASGDEAKQMNGRARNPYAARNGFNVNSGEETQCSPIGSPINPHCREGSGEYAVQPVNVQARYRLQSPPISFASGNPSFPTSPRDSALHSTPHVRSCSNSFPCDGFCRPNPSGQTFSPAMGRSPDFSNDPNMCMPPYPGGYTPSGFVMPPALATAAPPPRTDVMGRAPVPDGQASMRPKRPVSSPIACGHGSRYVSPVVLSVSPNYQVGSHPLCNPTGPQSVGCNNVHVAVGSVEPAQSAHSKMTTGDGSSTVSGGSGSSIREDLPLCSNDGVCTLINDRKHQRRFAHTCRLFPCYHGHIARHSKLFRHAPGQVAQSEELLNNGDGSKKLPAEALTSVSFSSISREAANAYRIIVSHRNKSYEIFGDWMNVRVHTFKRYLNQVYNVPPPSQVLVREEGNVPLDDDLESVGHYGIKQDGVVILRWKDEDEPLAVSLEQL
Protein: Dynein light intermediate chain (A0A0R4ICI6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU366047}.
Interaction partners:
Sequence:
MATTGRNTLLSVSTNVNNSTSESQNPEEEDGQNLWSSILSEVSTRSRSKLPSGKNVVVMGEVGSGKTTLVAKLQGVEEYMKGRGLEYLYFNVHDDDIDDQSRCNAWVLDGDLYHKGLQKFAISLENLEDSLILFVVDLSRPWLALDSLQKWGSVVRDFVDKLRVPPETMRELEHRLTKQFQEYVEPGSDLDAVPQRRNPESDEESVLLPLGENTLTHNLGLPIVVVCTKCDAISTLEKEHDYKDEHLDFIQSHIRRFCLQYGAALLYTSMKENKNLDLLYKYLVHRLYGFPFNSPAQVVEKDSVFIPSGWDNEKKIAILHENFQMVKAEDSFEDVIVKPPVRKFVHEKEVQAEDDQVFLVKLQSLLSKQPPVTAGRPVDPTNRAPTGSPRTTNRSAAANVANVMPMQSGGQTSEGVLANFFNSLLTKKAGSPGPGGQPAGGGSNTPGTVRKSGSKLGLTDVQAELDRISNKSDLDSSAPNATTPPAENDKS
Protein: Cysteine-rich repeat secretory protein 38 (Q9LRJ9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- RING-type E3 ubiquitin transferase
- Methylsterol monooxygenase 1-2
- Feruloyl CoA ortho-hydroxylase 2
Sequence:
MSSLKRIVWFPILAIAIQILSIHTVLSQSQNNAFLFHKCSDIEGSFTSKSLYESNLNNLFSQLSYKVPSTGFAASSTGNTPNNVNGLALCRGDASSSDCRSCLETAIPELRQRCPNNKAGIVWYDNCLVKYSSTNFFGKIDFENRFYLYNVKNVSDPSTFNSQTKALLTELTKKATTRDNQKLFATGEKNIGKNKLYGLVQCTRDLKSITCKACLNGIIGELPNCCDGKEGGRVVGGSCNFRYEIYPFVKTA
Protein: Protein disulfide isomerase-like 1-5 (AtPDIL1-5) (EC 5.3.4.1) (Protein disulfide isomerase 3) (AtPDI3) (Protein disulfide isomerase-like 3-1) (AtPDIL3-1) (A3KPF5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000305}.
Interaction partners:
- Endoplasmic reticulum oxidoreductin-1
- Endoplasmic reticulum oxidoreductin-2
- Protein disulfide-isomerase 5-3
- Protein disulfide-isomerase 5-1
- Protein disulfide-isomerase 5-4
- Thioredoxin domain-containing protein PLP3B
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Heat shock 70 kDa protein BIP3
- Heat shock 70 kDa protein BIP1
- Heat shock 70 kDa protein BIP2
Sequence:
MSLIPKPISKVSTFTFILLILLSFTIIIAYSSPDSNVESNEPGFDSDLDQLLAVDEQLQEDRPEQQSEAETVSKAQRIVLELNGDYTKRVIDGNEFVMVLGYAPWCARSAELMPRFAEAATALKEIGSSVLMAKIDGDRYSKIASELEIKGFPTLLLFVNGTSLTYNGGSSAEDIVIWVQKKTGAPIITLNTVDEAPRFLDKYHTFVLGLFEKFEGSEHNEFVKAAKSDDEIQFIETRDSDVAKLLFPDLKSNNVFIGLVKPEAERYTVYDGSYKMEKILEFLGSNKFPLFTKLTETNTVWVYSSPVKLQVMLFSKADDFQKLAQPLEDIARKFKSKLMFIYVDITNENLAMPFLILFGIEAGNKTVVAAFDNNLNSKYLLESDPSPNSIEEFCSGLAHGTVSRYYRSEPVPDNENASIVTVVGKTFDGLVLNSRENVLLEVHTPWCVNCEALSKQIEKLAKHFKGFENLVFARIDASANEHTKLQVDDKYPIILLYKSGEKEKPLKLSTKLSAKDIAVFINEELLKPKNGSAKDEL
Protein: Uncharacterized protein (Q387J9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSNGGVTAFPPEGPSLYGRKPGGSFYATLFSSGISAGFRFPEAPRHTSQLLVFLSNSINVAGAAVIGMEEMILKSVRDVLQVYNELGGDGTGTAPCLHQISLENLRSLADCFAHRPLLGPRAIGALLRMAVLVVKYAPLDALCDEGCNILNCLLQLLSCLPRSTVENEPLSILRVTRITIRNAMRRIGPCIAGTDGETFQGRICAGASVTDEALERDIIPWMEKHLLPLHIVTGDAARVELREDRHLALALLSYLPLNSAASSHRVALRLALLYLAETVAALLKVDAAVGGVEGTEREQACMFLRQANINFSSYSSVNVNLQTDEDAAGGCCITDGPPVPAAAVEDFLLAQEAAYRRDFTQLERCINREHDLRVTLERCIDEAKLRSGLQ