wanglab/gogpt-training-data huggingface dataset:
Protein: Long-chain-alcohol oxidase FAO4B (EC 1.1.3.20) (Long-chain fatty alcohol oxidase 4B) (Q94BP3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Ribokinase
Sequence:
MEDVRRRNRGHPLLRSKKRGEGYNHGFSPSQIQSLAVICQTFLPPETTSEQQAVNSFHVASSTQPPFTDEVAEMIVKNGRSEAVKVLRIILMILSFRFGTLLLCGSLCLDKSWPFVLKFSQLPLDKREAILRNWSRQSGFLLPFRITFFLAKFYTLFYFFSQTDENLKNPALEAIGYCIDGTERSSNKKSEADEKRRPLEKGIIETMHESDVTITQSLTEKGVHVARDDGDNVYRIRCDAVVVGSGSGGGVAAANLAKAGLKVLVLEKGNYFTAHDYSGLEVPSMLELYEKGGLLTTVDGKFMLLAGSAVGGGTAVNWSASIRTPDHVLQEWSEGSKIKFFGSQEYQSAMDEVTIRIGVTERCVKHGFQNQVLRKGCERLGLQVESVPRNSPEDHYCGLCGYGCRAGAKNGTDQTWLVDAVENGAVILTGIKAERFVLVDNTSSSNERKKRCVGVFASSVGGKIGKKFIIEARVTVSSAGSLLTPPLMLSSGLKNPNIGRNLKLHPVLMTWGYFPEKDSEFSGKMYEGGIITSVHHMNDTESGCKAILENPLIGPASYAGLSPWVSGPDLKERMIKYGRTAHLFALVRDLGSGEVMMENEVTYRTTKKDRENLRAGLRQALRVSVAAGAVEVGTYRSDGQKMKCEAITKEAMEEFLDEVDAVGGVGTKGEYWTTYFSAHQMGSCRMGVTAEEGALDENGESWEAEGLFVCDGSILPSAVGVNPMITIQSTAYCISSKIVDSLQNKTKV
Protein: Subtilisin-like protease SBT2.1 (EC 3.4.21.-) (Subtilase subfamily 2 member 1) (AtSBT2.1) (Q9SA75)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q84WS0}.
Interaction partners:
- At4g30500
- EP1-like glycoprotein 4 lectin family protein)
Sequence:
MDESSLVRFVFLLCLVSSSVFCLAESDQNATVSSAVYIVTLKDRPSVHFSGRESSDSKHSLTATSSQIYRTLNRSASIIRVHDSLLRNVLRKENYLKLYSYHYLINGFSAVLTRKQADRLAAREEVENVVLDFLVEKATTHTPQFLGLPRGAWLRDGGSEYAGEGVVIGFIDTGIDPTHPSFSDKISGHTYSVPPHFTGVCEVTIGFPPGSCNRKLIGARHFAESALSRGVLNSSQDDASPFDGEGHGTHTASVAAGNHGIPVVVAGHRLGNASGMAPRAHIAIYKALYKRFGGFAADIIAAIDQAAQDGVDIINLSITPNRRPPGIATFFNPIDMALLSAVKAGIFVVQAAGNTGPAPKSMSSFSPWIFTVGATSHDRVYSNSIILGNNVTIPGVGLASGTRIMHKLVLATHALRNGTTVMDAIYVGECQDSSSFDQKLVQGKILVCSYTVRFILGVSTIKQALLTAKNLTAAGLVFYIDPSATGFQMTSSPMDIPGILISSPQDSQALLRYYNSSLLRENGSGKIVGSASVAKIVGGMRPTYGITAPKVMYFSARGPDPEDDSFVDADIMKPNLVAPGNAIWGAWSPLGIGTNDFQGERFAMESGTSMSAPHVTGIAALIKQKFPHFTPAAIASALSTTASLSDRKGEHIMAQRTVLNPDISQSPATPFDMGSGFVNATAALDPGLIFDIGYNEYMKFLCGINGSSPVVLNYTGESCSSYNSSLAASDLNLPSVTIAKLVGTRAVLRWVTNIATTATNETYIVGWMAPDSVSVKVSPAKFTIGNGQTRVLSLVFRAMKNVSMASFGRIGLFGDRGHVVNIPVAVIYKIAV
Protein: ORF10 (E5LBS6)
Organism: Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Interaction partners:
Sequence:
MQTEATFILGDWEITVSNCRFTCSSLTCGPLYRSSGDYTRLRIPFSLDRLIRDHAIFGLVPNIEDLLTHGSCVAVVADANATGGNARRIVAPGVINNFSEPIGIWVRGPPPQTRKEAIKFCIFFVSPLPPREMTTYVFKGGDLPPGAEEPETLHSAEAPLPSRETLVTGQLRSTSPRTYTGYFHSPVPLSFLDLLTFESIGCDNVEGDPEQLTPKYLTFTQTGERLCKVTVYNTHSTACKKARVRFVYRPTPSARQLVMGQASPLITTPLGARVFAVYPDCEKTIPPQETTTLRIQLLFEQHGANAGDCAFVIMGLARETKFVSFPAVLLPGKHEHLIVFNPQTHPLTIQRDTIVGVAMACYIHPGKAASQAPYSFYDCKEESWHVGLFQIKHGPGGVCTPPCHVAIRADRHEEPMQS
Protein: Chronophin (EC 3.1.3.16) (EC 3.1.3.74) (Pyridoxal phosphate phosphatase) (PLP phosphatase) (Reg I-binding protein 1) (Q8VD52)
Organism: Rattus norvegicus (Rat)
Function: Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism. Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN. Thereby, regulates cofilin-dependent actin cytoskeleton reorganization, being required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phosphothreonines in LIMK1. Does not dephosphorylate peptides containing phosphotyrosine.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q96GD0}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q96GD0}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:Q96GD0}; Peripheral membrane protein {ECO:0000250, ECO:0000250|UniProtKB:Q96GD0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96GD0}. Cell projection, lamellipodium membrane {ECO:0000250|UniProtKB:Q96GD0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96GD0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96GD0}. Cell membrane {ECO:0000250|UniProtKB:Q96GD0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96GD0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96GD0}. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Diffusely distributed throughout the cytosol during pro-metaphase and metaphase. Detected at the dynamic cell poles during telophase. Detected at the cleavage furrow and contractile ring during cytokinesis. Transiently detected at the plasma membrane in late stages of cytokinesis. Detected at the midbody. {ECO:0000250|UniProtKB:Q96GD0}.
Interaction partners:
- Pyridoxal kinase
- Pyridoxine-5'-phosphate oxidase
- Aldehyde oxidase 1
- Aldehyde oxidase 3
- Aldehyde oxidase 4
- Aldehyde oxidase 2
- Pyridoxal phosphate phosphatase PHOSPHO2
- Cofilin-1
- Cofilin 2
- LIM domain kinase 1
Sequence:
MARCERLRGAALRDVLGQAQGVLFDCDGVLWNGERIVPGAPELLQRLAQAGKATLFVSNNSRRARPELALRFARLGFTGLRAEELFSSAVCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDPGDDPRVRAVLVGYDEHFSFAKLTEACAHLRDPDCLLVATDRDPWHPLTDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFQCITEDFSVDPARMLMVGDRLETDILFGHRCGMTTVLTLTGVSSLEEAQAYLAAGQHDLVPHYYVESIADLMEGLGGLSPPPQFPDPVDGGYRP
Protein: Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein) (O75052)
Organism: Homo sapiens (Human)
Function: Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity). In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.
Subcellular location: Cell projection, filopodium {ECO:0000250|UniProtKB:O54960}. Cell projection, podosome {ECO:0000250|UniProtKB:O54960}.
Interaction partners:
- Nitric oxide synthase 1
- Dexamethasone-induced Ras-related protein 1
- Uncharacterized protein C1orf226
- Uncharacterized protein
- Disks large homolog 4
- Protein scribble homolog
- Synapsin-2
- Synapsin-1
- Voltage-gated inwardly rectifying potassium channel KCNH2
- Alpha-1-syntrophin
Sequence:
MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV
Protein: Zinc finger protein 367 (C2H2 zinc finger protein ZFF29) (Q7RTV3)
Organism: Homo sapiens (Human)
Function: Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes.
Subcellular location: Nucleus {ECO:0000269|PubMed:15344908}.
Interaction partners:
Sequence:
MIRGFEAPMAENPPPPPPPVIFCHDSPKRVLVSVIRTTPIKPTCGGGGEPEPPPPLIPTSPGFSDFMVYPWRWGENAHNVTLSPGAAGAAASAALPAAAAAEHSGLRGRGAPPPAASASAAASGGEDEEEASSPDSGHLKDGIRRGRPRADTVRDLINEGEHSSSRIRCNICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPFVCSENGCLSRFTHANRHCPKHPYARLKREEPTDTLSKHQAADNKAAAEWLARYWEMREQRTPTLKGKLVQKADQEQQDPLEYLQSDEEDDEKRGAQRRLQEQRERLHGALALIELANLTGAPLRQ
Protein: MutL C-terminal dimerisation domain-containing protein (Q8C0U7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MFSSPIQMHHLLEEREADLEMQTISSTVNVMAANIPQNNDIPSQLEKWKDAPEVGCQPLPFETTLLRVRGTQRKKERRKKEPSSRGRVNVFSYGQVKLCSTGFITHVVQSEHAKSTETEHSFKNYARPGPVSAQETFGKRTHHAIETPDSSDLTSTLSKESSQPPNKRFCRTNTGYGTENKPVATDDNLALFQESCKESHTDRLLPDASSFPWCRYVSDGCRKIDKRGSFKQVVRRKLSLRSQVGSLEKFKRQYGKVSSSLDTEKDNNTEVRTHLDPQNEPDVLLKDKSHLDMSDGCEITTVEHSETCQPLSPILYPEKILFSKEDRLEQMPHLRESPITLEELSHCNRKADVEKSAASLASKLSKLKDSEKEMQTVGMTGHTSELPDSNPSWKDNSQCTRLDLDFCELLKNKLEKIESDMLPMADSATEDGPINKNSELHPNNTTDDTEKPETPLLFPCNDSKISRDSDVLIRTSEQPTGNPDSVGKVIMSQVEDGIGSQGGVCPQGDESKARSCSKNEPNAHCMDWQQHFDVTLGRMVYINRMTGLSTFVAPTDDLHTACTKDLTTVAVDVLLGNGAQYRCHPFRSDLVLPFLPRAQEERTMLRHNSNAVDAAAAAVSEPLQSLFSEWSNPVFARYPEVAVDVSSGQAESLAVKIHNVLYPYRFTKEMIHSVKVLQQVDNKFIACLMSTRMDEDGRTGGNLLVLVDQHAAHERIRLEQLITDSYEKQDPQSAGRKKLLSSTIIPPLAITVSEEQRRLLRSYHKHLEDLGLELLFPDASDSLILVGKVPLCFVEREASELRRGRSTVTKSIVEELIREQVELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDRLSLEESCRLIEALSLSQLPFQCAHGRPSMLPLADLDHLEQEKQVKPNLAKLRKMVRAWHLFGKTEQNLQQPIRPCEPP
Protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (Q9V3L4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSEVHITSDTRSINENKNINYNSYITCKQSSPKFNCGTEDGEEDWESE
Protein: Fms-related tyrosine kinase 3 ligand (Flt3 ligand) (Flt3L) (SL cytokine) (P49771)
Organism: Homo sapiens (Human)
Function: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Subcellular location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Interaction partners:
- Receptor-type tyrosine-protein kinase FLT3
- Ubiquitin-like protein FUBI
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
- Small ribosomal subunit protein uS13
- Kit ligand
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS28
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS5
Sequence:
MTVLAPAWSPTTYLLLLLLLSSGLSGTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTAPQPPLLLLLLLPVGLLLLAAAWCLHWQRTRRRTPRPGEQVPPVPSPQDLLLVEH
Protein: Olfactory receptor 10P1 (Olfactory receptor 10P2) (Olfactory receptor 10P3) (Olfactory receptor OR12-7) (Q8NGE3)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- G protein-coupled receptor kinase 3
- Beta-adrenergic receptor kinase 1
- Beta-arrestin-1
- Beta-arrestin-2
Sequence:
MAGENHTTLPEFLLLGFSDLKALQGPLFWVVLLVYLVTLLGNSLIILLTQVSPALHSPMYFFLRQLSVVELFYTTDIVPRTLANLGSPHPQAISFQGCAAQMYVFIVLGISECCLLTAMAYDRYVAICQPLRYSTLLSPRACMAMVGTSWLTGIITATTHASLIFSLPFRSHPIIPHFLCDILPVLRLASAGKHRSEISVMTATIVFIMIPFSLIVTSYIRILGAILAMASTQSRRKVFSTCSSHLLVVSLFFGTASITYIRPQAGSSVTTDRVLSLFYTVITPMLNPIIYTLRNKDVRRALRHLVKRQRPSP
Protein: Photosystem II reaction center protein L (PSII-L) (Q6ENF8)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01317}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01317}.
Interaction partners:
- Photosystem II reaction center protein J
- Cytochrome b559 subunit beta
- Photosystem II reaction center protein T
- 33 kDa subunit of oxygen evolving system of photosystem II
- Photosystem II reaction center protein I
- Uncharacterized protein
- Photosystem II CP47 reaction center protein
- Cytochrome b6
- Cytochrome b559 subunit alpha
- Photosystem II reaction center protein K
Sequence:
MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
Protein: Glucose-1-phosphate adenylyltransferase large subunit 2, cytosolic (OsAGPL2) (OsAPL2) (EC 2.7.7.27) (ADP-glucose pyrophosphorylase AGPL2) (ADP-glucose synthase AGPL2) (Protein FLOURY ENDOSPERM 6) (Protein GRAIN INCOMPLETE FILLING 2) (Protein SHRUNKEN 1) (Q7G065)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in synthesis of starch. Catalyzes the synthesis of ADP-glucose, a molecule that serves as an activated glycosyl donor for alpha-1,4-glucan synthesis. Essential for starch synthesis in seed endosperm. Is essential for both catalytic and allosteric regulatory properties of the cytosolic heterotetramer enzyme.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:17406793}.
Interaction partners:
- Granule-bound starch synthase 1, chloroplastic/amyloplastic
- Starch synthase, chloroplastic/amyloplastic
- Soluble starch synthase 3a, chloroplastic/amyloplastic
- ADP-glucose pyrophosphorylase
- Soluble starch synthase 1, chloroplastic/amyloplastic
- Sucrose synthase 4
- phosphoglucomutase
- 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic
- Alpha-1,4 glucan phosphorylase
- starch synthase
Sequence:
MQFMMPLDTNACAQPMRRAGEGAGTERLMERLNIGGMTQEKALRKRCFGDGVTGTARCVFTSDADRDTPHLRTQSSRKNYADASHVSAVILGGGTGVQLFPLTSTRATPAVPVGGCYRLIDIPMSNCFNSGINKIFVMTQFNSASLNRHIHHTYLGGGINFTDGSVQVLAATQMPDEPAGWFQGTADAIRKFMWILEDHYNQNNIEHVVILCGDQLYRMNYMELVQKHVDDNADITISCAPIDGSRASDYGLVKFDDSGRVIQFLEKPEGADLESMKVDTSFLSYAIDDKQKYPYIASMGIYVLKKDVLLDILKSKYAHLQDFGSEILPRAVLEHNVKACVFTEYWEDIGTIKSFFDANLALTEQPPKFEFYDPKTPFFTSPRYLPPARLEKCKIKDAIISDGCSFSECTIEHSVIGISSRVSIGCELKDTMMMGADQYETEEETSKLLFEGKVPIGIGENTKIRNCIIDMNARIGRNVIIANTQGVQESDHPEEGYYIRSGIVVILKNATIKDGTVI
Protein: Arp2/3 complex 34 kDa subunit (Q53R19)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU364015}.
Interaction partners:
Sequence:
MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR
Protein: Ras-like protein 1 (EC 3.6.5.2) (P08647)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Participates in the process of sexual differentiation and the determination of cell shape. Essential for mating and for recognition of the mating pheromone, but not for vegetative growth. Does not regulate the intracellular cAMP level. Regulates two downstream pathways, namely the byr2/byr1/spk1 mitogen-activated protein kinase cascade and the cdc42 small G protein pathway. The former is relevant to mating and sporulation, whereas the latter is relevant to mating, cell growth and cell morphology.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Rho guanine nucleotide exchange factor scd1
- Adenylate cyclase
- Protein kinase byr2
- Protein scd2/ral3
- cAMP-dependent protein kinase catalytic subunit
- Protein ste6
- Serine/threonine-protein kinase shk1/pak1
- GTPase-activating protein
- Cell division control protein 42 homolog
- Protein kinase byr1
Sequence:
MRSTYLREYKLVVVGDGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRVKDKDTFPVVLVANKCDLEAERVVSRAEGEQLAKSMHCLYVETSAKLRLNVEEAFYSLVRTIRRYNKSEEKGFQNKQAVQTAQVPASTAKRASAVNNSKTEDEVSTKCCVIC
Protein: Transcription factor ABA-INDUCIBLE bHLH-TYPE (AtAIB) (Basic helix-loop-helix protein 17) (AtbHLH17) (bHLH 17) (Transcription factor EN 35) (bHLH transcription factor bHLH017) (Q9ZPY8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator. Regulates positively abscisic acid (ABA) response. Confers drought tolerance and sensitivity to ABA.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:17828375}.
Interaction partners:
- Protein TIFY 10A
- Protein TIFY 10B
- Transcription factor bHLH92
- Protein TIFY 11A
- Protein TIFY 6A
- Protein TIFY 5B
- Protein TIFY 5A
- Bidirectional sugar transporter SWEET15
- Protein TIFY 11B
- Protein TIFY 9
Sequence:
MNMSDLGWDDEDKSVVSAVLGHLASDFLRANSNSNQNLFLVMGTDDTLNKKLSSLVDWPNSENFSWNYAIFWQQTMSRSGQQVLGWGDGCCREPNEEEESKVVRSYNFNNMGAEEETWQDMRKRVLQKLHRLFGGSDEDNYALSLEKVTATEIFFLASMYFFFNHGEGGPGRCYSSGKHVWLSDAVNSESDYCFRSFMAKSAGIRTIVMVPTDAGVLELGSVWSLPENIGLVKSVQALFMRRVTQPVMVTSNTNMTGGIHKLFGQDLSGAHAYPKKLEVRRNLDERFTPQSWEGYNNNKGPTFGYTPQRDDVKVLENVNMVVDNNNYKTQIEFAGSSVAASSNPSTNTQQEKSESCTEKRPVSLLAGAGIVSVVDEKRPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAISYIKELQEKVKIMEDERVGTDKSLSESNTITVEESPEVDIQAMNEEVVVRVISPLDSHPASRIIQAMRNSNVSLMEAKLSLAEDTMFHTFVIKSNNGSDPLTKEKLIAAFYPETSSTQPPLPSSSSQVSGDI
Protein: T-cell surface glycoprotein CD3 epsilon chain (A0A0G2K986)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
FDTCEISLDFSPPTSFPFLLSPEYEVSISGTSVELTCPLENEDNLKWEKNDKVLPDKNEKHLVLEDFSEVKDSGYYVCYTESSRKNTYLYLKARVCENCMEVDLTAVSIIIIVDICITLGLLMVVYYWSKKRKAKAKPVTRGTGTGGRPRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRAV
Protein: Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (Mitogen-activated protein kinase kinase 3) (zMKK3) (Q9DGE0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is necessary for blastomere cleavage.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Binds to microtubules. {ECO:0000250}.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase 7.
- Mitogen-activated protein kinase 12
- mitogen-activated protein kinase
- Mitogen-activated protein kinase 14B
- Mitogen-activated protein kinase 14A
- Mitogen-activated protein kinase.
- mitogen-activated protein kinase
- mitogen-activated protein kinase
- mitogen-activated protein kinase kinase kinase
- Mitogen-activated protein kinase
Sequence:
MEGGSDKESKVFCDSPSPNPKGEMSVPSNVRGKKKLPKELKLPKEVFEKPAPAPTPPRDLDSKAYVTIGEKNFVVKADDLEQIGELGRGAYGVVDKMRHVPSGVIMAVKRIRATVNTQEQKRLLMDLDISMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYKQVHEKGKTIPEDILGKITVSIVKALEHLHSNLSVIHRDVKPSNVLINMQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPETNQKGYNVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADRFSADFVDFTSQCLRKNSTERPTYTELMQHPFFTLHDSKDTDVASFVKTILGD
Protein: Mitogen-activated protein kinase 2 (AtMPK2) (MAP kinase 2) (EC 2.7.11.24) (Q39022)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Mitogen-activated protein kinase kinase 3
- Protein-tyrosine-phosphatase PTP1
- Peroxiredoxin-2F, mitochondrial
- Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein
- Mitogen-activated protein kinase kinase 7
- Mitogen-activated protein kinase kinase 1
Sequence:
MATPVDPPNGIRNQGKHYFSMWQTLFEIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREEDLEFIDNPKAKRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEALQHPYMAPLYDPSANPPAQVPIDLDVDEDEDLGAEMIRELMWKEMIHYHPEAATINNNEVSEF
Protein: Myosin XVIIIb (E9PV66)
Organism: Mus musculus (Mouse)
Interaction partners:
- Actin, cytoplasmic 2
- Unconventional myosin-If
- Mitogen-activated protein kinase kinase kinase 1
- Cytospin-A
- Thymosin beta 15b like
- F-actin-uncapping protein LRRC16A
- Myosin light chain 1/3, skeletal muscle isoform
- Myosin light chain 6B
- Myosin light polypeptide 6
- Unconventional myosin-Ic
Sequence:
MAISSRLALWEQKIREEDKSPPPSSPPPLFSVIPGGFIKQLVRETEKESKEARRRKAAAFTAPEVEIPAVPTNQTNKTNNVPKPGSQQTSQDSSSTTQNSADIPGKEPPGAGDKDSTPVTSTSGERPQESGPTGTPAKRTLPFKRGVRRGDVLLMVAKLDPELAKADQKVQPRDVPVDKTPAPAKDSGGTKKGVTTGTSSAPQPSMPEKTRTRGVGDTGQSTKGGKCQGTEGKGSRDPQTIGQKEGESQSTEEQGTRSQAQEAGNKEQLGTAEKEGGGPPKKMEKEDEPKVAGAEVRPVEPPVPLRKWGGFLGWRSKWDSPQSKDRVTESHRKDEKTGDLQSPAVDRSCGQLAEPTGQPSGPTGQPSGPTGQLSESTGQPSGPTGQPAGPTGQPAGPTGQPAGPTGQPAGPTGQQQEAPVKMEGKVGRPQKKLVTPRKPRELPGVAAKTQNPEESCKAPDRIPTTGISAEAAKRDGQPESRVQGAGEPRVCTEEEVDVVKPQAEGHVESIPEVVMERLSTLRPMEEKQILQDPDRGGQSGDSDQAYEDRWYEAQKVWLVQKDGFTLATVLKPDEGTADPPAGRVRLCIDADRTVIEVDEEQVHPANPSELDQAEDLASLVSVNESSVMNTLLQRYRAQLPYTCSGPDLITLQPQTTTVPSSGKVPRGRQDGLPAHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTTCCEQVLEHLVGMAGSVDGRVSVEKLRATFTVLRAFGCVSTGHSRRATRFAMVMSLDFNATGRVTAAQLQTVLLENSRVARQPQGEGNFEVFSQLLAGMDVDLRTELNLHQMAESSAFGMGLWSKPEDKQKAATAFSQLRGAMELLGISEGEQQAIWRVLAAIYHLGAAGACKVGRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGPQRQGLQDNEACSGLKMTGVECVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDTPGFQNPRHQGKDRAATFEELCYNYAQERLQLLFYHRTFVSTLERYKEEGIPVPFDLPESSPGTTVAVVDQNPSQVHLPAGRGAEDAGGLFWVLDEEVRVQGSSDSTVLERLRAAFEKKKEAGAEEPPSMRTCEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLAALEAPQILQQSKREELQSLFQARAKLPPVCRAVAGLEGTSQQALHRSRVVRRAFASSLAAVKRKAPCAQIKLQMDALISLLRRSRLHFIHCLVPTTVESKAGQRTPSPSQPSGDQGVANEPTALDIPALRVQLAGSHILEALRLHRAGYAEHMGLAQFRRRFQVLDPALLKKLDLTSEELDERKVVEELLKTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSRNIVLFQAACRGFLSRQEYKKLKIRRLATLCIQKNLAVFLKVKDWPWWGLLASLRPLLSSTLGTEQLRAKEEELTLLRQKLQKSENSRSELRQNTDLLESKITDLTSELADERFKGDVACQALESERAERLQALREVQELKTKYQQVQDALGEVQKQLEEAQQRIQGANLEEKPAGGADEWQMRLDCAQMENDFLRKRLQQCEERLDSEMKARTELEQKLGELQSAYEEAKKMAHQLKRKCHHLTWDLEDTRVLLENQQSRNHELEKRQKKFDLQLAQALGESMFEKSLREKVSQENNGVRWELGQLQQQLEQKEQEASKLKQEVERLQGQKRELLSCASVGDQGVASLKERVWELETNALEQQKIHSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQVALHEKHDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATIEDSKTSISKEELEKVHSQLEQSEAKCEDALKTQKVLTADLENMHSELENVTRSKSLVDEQLYRLQFERADLLKRIDEDQGDLNDLMQKHKDLIAQSAADIGQIQELQLQLEETKKEKQKLREQLHMAQLRIQYLEQSTVERAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSMIKMGEELSRAVKAEAQQRENSQYYQQRLEELKAEMQELAQREEEASRRCMELEKYVEELATVRQTLQTDLETSIRRIADLQAALEEVVSSDSDTESVQTAVDCSSRSGKEGDNVSVISSQPEGSLQSWMSCSLSLATDSVRIPSGQSVVSSSFHSPRVSEEAGDSERLRTASSALSGAWDAARDASKAGSASLHPVFPQKPYHLGDGEGFAVHRKSTLERSGPLSSSPPSQRTAVSPPSRDKLPSPSAALSEFVEELRRKRAQRGQGSTLHLGDGPVLPIFQTTRASSLRRGRASSDEGDLSLKTRVKSPLGAEGIPGATAGLSRSTSLKCISSEGPEDITLLPDKQKTRFGSCESLLESGPCTRRKLSSPTGLLSPTLRPRRPCLESSVDDAISLELGKEPLVFQNRQFSHLMEETLDSDPFSWKLPSLNYRRQTKVDFDDFLPAIRKSDTPSSGAAKDGKEASKHPGVHFEMGEAADRSFLSGIKTILKKSPEVKEDPAHLSDSSSSSSSIVSFKSTGGTGSGPRVPRLQGDGGERMSPEHRDPGSARRDDDVESIMRKYLQQ
Protein: Transcription factor 7 like 2 (A0A8I6A761)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPQLNGGGGDDLGANDELISFKDEGEQEEKNSENSSAERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAIQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSAFATYKVKAAASAHPLQMEAY