wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein C3H8.05c (Q10141)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Protein mms22
- Pre-mRNA-splicing factor brr2
- Pre-mRNA-splicing factor sap114
- Pre-mRNA-splicing factor spp42
- Pre-mRNA-splicing factor cwf10
- Uncharacterized protein C211.05
- U2 snRNP component prp10
- Pre-mRNA-splicing factor sap145
- Pre-mRNA-splicing factor sap61
- Pre-mRNA-splicing factor sap62
Sequence:
MAEIIHHSNVFTWAFHVSEYDGAPLLLLGSFSSVASVSLKRSGDLLLFERFTLPARTRSVALLSSHFLQSESGRHSIANILIATENGKCYLLQLVKTPEKAFPTIRIRDEFVLDTRMYNHEQLGKSIDLCPNASLWATNSFAGDIVFFFSHHPSLSKQVFAQLSIDGIILHTIFVPPKRSSSSCVTYVCLFLDSNSNPRINVYRWSKTETFSDASSYITFSIPVPSEFSLASHIIPCSNIPDHFLVLLETKICLLSVPQIECGDLKFLQTDLPCSGSHNYPLSIANDNETPNCCYLTYENGDLYRIRYSILSIDINLIGKTGSSLGNLILPCYPYIVFCGDCSDTLVYDVSVSPMSFFGSLIACAPMWDFVYSSSRHNTLLDEDINCNTVYATAGIGKSGCLVTMRYGCSSTTLLEAILTEGAVLSGIINSNHNSEFYAWLTYPWQTQILRLHLDGVVEDVTESLFLDDIKALYVINYQNTFIIITGKSIYAVTPSCTKYNLLEVSGDEEFVLAAYNELIFIVKKDLMNFKSQLLTLKLNTLSNGTLELQSLPDSFDLHDVPTCITSFSLERKLLVILVHPSPYFECVFYDETSHSSVYKVPLTGFQFGYLPHSISYLRKSNRAVYVLISSNSTLLTVYVTLTLEGVPDFKVYSNPISTDLPLTLQSPSDEFSTIYAWSDYLYIVGIDMETEQPTLNQILEVNDSFTCVSGIYDIPNKFQNSESRIIVYYSNNTLYLSELWLPQRTFSSKLNLAATPKRLLVDKYTNTLIIGCCHVLVNEITTSGLAFYDLTNSRLFPVNWPSMDIKGKPIFKPEELLYSMSFWIVADDQKRKYRYLCIGTGVRKNGLTTGRLLILTMNKDHDSNAIELRNVITINMKDPIYSVCSIGKHGLCYATGRKIGVKMLDLDSKKFCNSDCELPVRSPIVSMSTYKDYVYTSSLRDSVAVFQYDSENNSLNLVCSDTSSRLGIDCFYISQKKLLFSCDKDRLLTCFKVEGEVCTSTREQMLQPILTTVSQTKTNALTNHLKYSVIRVDKDNHNIVWGLMGCTLDGNIFKILMPNDPTSSDTIIYSDT
Protein: Fc receptor-like protein 6 (FcR-like protein 6) (FcRL6) (Fc receptor homolog 6) (FcRH6) (IFGP6) (Q6DN72)
Organism: Homo sapiens (Human)
Function: Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18991291, ECO:0000269|PubMed:20933011}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLLWTAVLLFVPCVGKTVWLYLQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMGAATVQSRGQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTKLHPLRSALRLLFSFHKDGHTLQDRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAPCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVPWLPASLLGLMVIAAALLVYVRSWRKAGPLPSQIPPTAPGGEQCPLYANVHHQKGKDEGVVYSVVHRTSKRSEARSAEFTVGRKDSSIICAEVRCLQPSEVSSTEVNMRSRTLQEPLSDCEEVLC
Protein: Probable ATP-dependent RNA helicase DDX53 (EC 3.6.4.13) (Cancer-associated gene protein) (Cancer/testis antigen 26) (CT26) (DEAD box protein 53) (DEAD box protein CAGE) (Q86TM3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:11922625}.
Interaction partners:
- Calreticulin
- T-cell surface glycoprotein CD8 alpha chain
- Patched domain-containing protein 1
- Programmed cell death 1 ligand 1
- Cancer/testis antigen 1
Sequence:
MSHWAPEWKRAEANPRDLGASWDVRGSRGSGWSGPFGHQGPRAAGSREPPLCFKIKNNMVGVVIGYSGSKIKDLQHSTNTKIQIINGESEAKVRIFGNREMKAKAKAAIETLIRKQESYNSESSVDNAASQTPIGRNLGRNDIVGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPGQRRKEFYFLS
Protein: Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1) (Q6NXR0)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, cilium, flagellum {ECO:0000269|PubMed:37195149}. Lipid droplet {ECO:0000269|PubMed:37195149}. Note=Expressed in the sperm mitochondrial sheath. {ECO:0000269|PubMed:37195149}.
Interaction partners:
Sequence:
MATSKLPVVPGEEENTILMAKERLEALRTAFESGDLPQAASHLQELLASTESIRLEVGVTGESGAGKSSLINALRGLEAEDPGAALTGVMETTMQPSPYPHPQFPDVTLWDLPGAGSPGCPADKYLKQVDFSRYDFFLLVSPRRCGAVETRLAAEILCQGKKFYFVRTKVDEDLAATRTQRPSGFREAAVLQEIRDHCAERLREAGVADPRIFLVSNLSPARYDFPTLVSTWEHDLPSHRRHAGLLSLPDISLEALQKKKAMLQEQVLKTALVLGVIQALPVPGLAAAYDDALLIHSLRGYHRSFGLDDDSLAKLAEQVGKQAGDLRSVIRSPLANEVSPETVLRLYSQSSDGAMRVARAFERGIPVFGTLVAGGISFGAVYTMLQGCLNEMAEDAQRVRIKALEDDEPQPEVSLEVASDNGVEKGGSGEGGGEEAPLSTCRKLGLLLKYILDSWKKHDSEEK
Protein: EF-hand calcium-binding domain-containing protein 7 (A8K855)
Organism: Homo sapiens (Human)
Function: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia.
Subcellular location: Cell projection, cilium membrane {ECO:0000250|UniProtKB:Q8VDY4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8VDY4}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8VDY4}. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner. {ECO:0000250|UniProtKB:Q8VDY4}.
Interaction partners:
- IQ domain-containing protein E
- Limbin
- Sperm surface protein Sp17
- A-kinase anchor protein 14
- EvC complex member EVC
Sequence:
MAISPRSDATFSSQKSTPSESPRTKKFPLTEEEIFYMNCRAAYLTVFKSSLENIISKDQLYLALQHAGRNPSQKTINKYWTPQTAKLNFDDFCIILRKEKPTSKAELLKSFKQLDVNDDGCILHTDLYKFLTKRGEKMTREEVNAIINLADVNADGKFDYIKFCKLYMTTNEQCLKTTLEKLEVDSKLMRHQFGNHIEGSPERDPSPVPKPSPKITRKTDPETFLNKGDTRSSLLSATRKFKTSVSFTVTMGANGNRNSKLMEPNLIKDWQHMQSKGCFFLEEDGEIISHQYRMQIAQRSMVYLTIKPLNLSQVEGKPSPWLSVDTALYILKENESQANLQLVCFTELRNREVFGWTGELGPGIYWLIPSTTGCRLRKKIKPVTDEAQLVYRDETGELFLTKEFKSTLSDIFEVIDLDGNGLLSLEEYNFFELRTSGEKCDEDAWAVCRENFDTKRNELTRQGFMDLNLMEANDREGDPCDLWVTLHSMGYNKALELTEACPFVIDIYAEKCKPKIKAVHMEACSGQLEKAICKSVLSNGDAKVMDGYENIIVHTYSCDTWITSVIENKSDEKVIIHISNELSKNCINNRGLNIFAVEVGPKSTMVCQHVMPLNERQEWIYYCIYSLIS
Protein: Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-B) (Asparagine-linked glycosylation protein 10 homolog B) (Q3UGP8)
Organism: Mus musculus (Mouse)
Function: Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity). When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 (By similarity). Has a role in maintenance of cochlear outer hair cell function.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q5I7T1}; Multi-pass membrane protein {ECO:0000255}. Note=Also detected at the plasma membrane. {ECO:0000250|UniProtKB:O88788}.
Interaction partners:
- Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Sequence:
MAQLEGYYFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGRFSLSQWDPMITTLPGLYLVSVGVVKPASWLLGWSEHVICSIGVLRFVNLLFSVGNFYLLYLLFRKVQPRNKASSSIQRILSTLTLAVFPTLYFFNFLYYTEAGSVFFTLFAYLMCLYGNHRTSALLGFCGFMFRQTNIIWAAFCAGHLIAQKCSEAWKIELQKKKEERLAPTKGPLSELRRVLQFLLVYAMSLKNLRMLFLLTWPYVLLLLAFFAFVVVNGGIVVGDRSSHEACLHFPQLFYFFSFTAFFSFPHLLSLTKVKTFLSLVWKRRVQFSVVTLVSILLVWKFTYVHKYLLADNRHYTFYVWKRVFQRHEVVKYLLVPAYIFAGWAIADSLKAKSIFWNLMFFVCLVASTVPQKLLEFRYFILPYIIYRLNIPLPPISRLVCELGCYTVVNFVTFYIFLNKTFQWPNSQDIQRFMW
Protein: Double-strand break reduction protein (P33230)
Organism: Escherichia coli (strain K12)
Function: Helps to maintain the integrity of the chromosome by lowering the steady-state level of double strand breaks. This region of DNA acts as an antitoxin to toxin RalR, a DNase, but it seems to be sRNA RalA that has the antitoxin activity and not this putative protein. Therefore the identity of this as a protein-coding gene has been cast into doubt.
Interaction partners:
- Uncharacterized protein YdaQ
- Endodeoxyribonuclease toxin RalR
- Killing protein KilR
- Protein RacC
- Protein RecT
- Exodeoxyribonuclease 8
- Uncharacterized protein YdaE
Sequence:
MYKITATIEKEGGTPTNWTRYSKSKLTKSECEKMLSGKKEAGVSREQKVKLINFNCEKLQSSRIALYSN
Protein: Cation-chloride cotransporter 1 (AtCCC1) (Protein HAPLESS 5) (Q2UVJ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cation/chloride cotransporter that mediates potassium-chloride and sodium-chloride cotransports. Involved in plant development and Cl(-) homeostasis. May be involved in long distance Cl(-) transport. Does not function as an H(+)-dependent cotransporter.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Vacuolar iron transporter 1
- Protein HAPLESS 2
- Vacuolar iron transporter homolog 1
- Vacuolar iron transporter homolog 2.1
- Vacuolar iron transporter homolog 2
- Vacuolar iron transporter homolog 3
- Metal transporter Nramp4
- Putative metal tolerance protein C3
- Metal transporter Nramp3
- Fe
Sequence:
MDSGDIEEAGGNGEEEFRSGPRLGGSKYRPVVAHDRAVVEMSSIDPGSSSSTLKNIKVVAPGDVGAGVRGPEDGVNGHQKESKLELFGFDSLVNILGLKSMTGEQIQAPSSPRDGEDISITQGHPKPPALKMGTMMGVFVPCLQNILGIIYYIRFTWIVGMAGIGQGLVLVFLCGLCTFLTTISLSAIATNGAMKGGGPYYLIGRALGPEVGISIGLCFFLGNAVAGALYVLGAVETFLKAFPAAGIFRETITKVNGTAVSESIQSPNSHDLQVYGIVVTILLCFIVFGGVKMINRVAPAFLVPVLLSIFCIFIGIFLAKTDDPDNGITGLRLKSFKDNWGSAYQMTNDAGIPDPTGGTYWSFNELVGLFFPAVTGIMAGSNRSASLKDTQKSIPVGTLAATLTTTSLYLISVLFFGAVATRDKLLTDRLLTATIAWPFPAIVHVGIILSTLGAALQSLTGAPRLLAAIANDDILPILNYFKVADTSEPHIATLFTAFICIGCVVIGNLDLITPTVTMFYLLCYSGVNLSCFLLDLLDAPSWRPRWKYHHWSLSFVGASLCIVIMFLISWSFTVVAIALASLIYKYVGLKGKAGDWGDGFKSAYFQLALRSLRSLGANQVHPKNWYPIPLVFCRPWGQLPENVPCHPKLADFANCMKKKGRGMSIFVSILDGDYYECAEEAKEACKQLATYIEYKRCEGVAEIVVAPNMTEGFRGIIQTMGLGNLKPNIVVMRYPEIWRRENLTEIPSTFVGIINDCITANKAVVIIKGLDEWPNEYQRQYGTIDLYWIVRDGGLMLLLSQLLLTKESFESCKIQLFCIAEEDSDAEALKADVKKFLYDLRMHAEVIVVTMKSWDIRSEGNSQEDSLEAFDAAQRRISDYLGEIKRQGSNPLLANGKPMVVNEQQVEKFLYTMLKLNSTILSYSRMAAVVLVSLPPPPLNHPAYFYMEYMDLLVENVPRMLIVRGYHRDVVTLFT
Protein: LRR receptor-like serine/threonine-protein kinase FLS2 (EC 2.7.11.1) (Protein FLAGELLIN-SENSING 2) (Protein FLAGELLIN-SENSITIVE 2) (Q9FL28)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Flagellin-binding to the receptor is the first step to initiate the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6), resulting in enhanced resistance against pathogens. Binding to the effector AvrPto1 or to the phosphatase hopD2 from Pseudomonas syringae blocks the downstream plant immune response.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24923602, ECO:0000269|Ref.32}; Single-pass type I membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:24923602, ECO:0000269|Ref.32}; Single-pass type I membrane protein {ECO:0000255}. Note=Internalization by endocytosis, especially in response to pathogen-associated molecular patterns (PAMPs e.g. flg22) recognition (PubMed:24923602, Ref.32). Accumulates at the plasma membrane, in an ACD6-dependent manner, in response to salicylic acid (SA) signaling, thus priming defenses (PubMed:24923602). {ECO:0000269|PubMed:24923602, ECO:0000269|Ref.32}.
Interaction partners:
- BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1
- Somatic embryogenesis receptor kinase 4
- Elongation factor Tu, chloroplastic
- Mitogen-activated protein kinase kinase kinase 1
- Serine/threonine-protein kinase BIK1
- Elongation factor Tu
- U-box domain-containing protein 13
- Putative RPP1-like disease resistance protein
- Probable WRKY transcription factor 29
Sequence:
MKLLSKTFLILTLTFFFFGIALAKQSFEPEIEALKSFKNGISNDPLGVLSDWTIIGSLRHCNWTGITCDSTGHVVSVSLLEKQLEGVLSPAIANLTYLQVLDLTSNSFTGKIPAEIGKLTELNQLILYLNYFSGSIPSGIWELKNIFYLDLRNNLLSGDVPEEICKTSSLVLIGFDYNNLTGKIPECLGDLVHLQMFVAAGNHLTGSIPVSIGTLANLTDLDLSGNQLTGKIPRDFGNLLNLQSLVLTENLLEGDIPAEIGNCSSLVQLELYDNQLTGKIPAELGNLVQLQALRIYKNKLTSSIPSSLFRLTQLTHLGLSENHLVGPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTVGFNNISGELPADLGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMTGEIPRGFGRMNLTFISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLIGKLQKLRILQVSYNSLTGPIPREIGNLKDLNILYLHSNGFTGRIPREMSNLTLLQGLRMYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQIPALFSKLESLTYLSLQGNKFNGSIPASLKSLSLLNTFDISDNLLTGTIPGELLASLKNMQLYLNFSNNLLTGTIPKELGKLEMVQEIDLSNNLFSGSIPRSLQACKNVFTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQSFGNMTHLVSLDLSSNNLTGEIPESLANLSTLKHLKLASNNLKGHVPESGVFKNINASDLMGNTDLCGSKKPLKPCTIKQKSSHFSKRTRVILIILGSAAALLLVLLLVLILTCCKKKEKKIENSSESSLPDLDSALKLKRFEPKELEQATDSFNSANIIGSSSLSTVYKGQLEDGTVIAVKVLNLKEFSAESDKWFYTEAKTLSQLKHRNLVKILGFAWESGKTKALVLPFMENGNLEDTIHGSAAPIGSLLEKIDLCVHIASGIDYLHSGYGFPIVHCDLKPANILLDSDRVAHVSDFGTARILGFREDGSTTASTSAFEGTIGYLAPEFAYMRKVTTKADVFSFGIIMMELMTKQRPTSLNDEDSQDMTLRQLVEKSIGNGRKGMVRVLDMELGDSIVSLKQEEAIEDFLKLCLFCTSSRPEDRPDMNEILTHLMKLRGKANSFREDRNEDREV
Protein: Tyrosine-protein kinase receptor (EC 2.7.10.1) (A0A0C4UQS4)
Organism: Nilaparvata lugens (Brown planthopper)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MEDSACPGCSLRPTNVGRRTRRGGGGLRGGYGDDVSWGVVSVLAAVCCLLLCLANPVEAFASLGTELRPRVDLSTDRSSPDARGVCQSLDIRNAAREFHQLQGCQVVEGFVQIVLMDKAVESEFANFSFPELREITGYLLLYRIDGLRTLSNLFPNLAVIRGNTLFFNYALVVFEMLHLQEMGLKSLTDIVRGAVHISKNPMLCYVDTIDWDKIARSSQGGHFITGNKKKNECPICQTNAVCPTSATNDNLCWNIQHCQKFCSKCEEGTACMDDGTCCDKNCLGGCNGTGPTNCIACRGYLFQGTCVATCPVQTYQYLQRRCVLEKECYDMPKPREIMSEEVRPQPWKPFMNQCLIDCPPNYAEAPIDNFRGLDPDRTYYRCEPCKGPCKKECEGLNVDSISSSQRLRGCTYIKGSLEIQIRGGYNVVKELENNLNMIEEINGYLKIVRSFPLVSLNFLKKLKVIHGEKLESGKYALVVLDNQNLVELWDFGPSREERLRITRGKLFFHFNPKLCYFKIDNLRKYLGMPEFTDNEVARNSNGDKVACNISLLDARVETRSSKGVIIKWKEFEHYDPRTLLGYIIYFIEAPYQNISLYDGRDACGGDGWRVIDVSPLEKDNETTTLNEDKNKTKHMSQLITQLKPYTQYAFYVKTYTIASENSGAQSPIIYFRTEPDIPSMPQNLVAKIESSSEIKVAWQPPLNPNGNVTHYLITAKWERDDSEFLAQRNYCEEPLTSIVDVTNQAGKWTLVNDDDVYTGGKPDDCVCMDDKKVNKKKQQEKEIQFQIQFEDTLQNLVYIKRSSLRDKREISLRDGKTITENHFAESDIRMKTVPVSTDLEVQRLENEPQVKILLQGKTSYVIRGLHHFAQYTISVSACRQRDETDKLIMTNNCSTHSIISARTKKLANADVVSEIWHEVIENPVNHTQPIVKLYWKEPPAPNGLIVMYQISHWLVFENQQHKKTHCISRRQFLEEGNSHTLTNLAPGNYSYQVCATSLAGLANCSQSPLRYFEIQGYSSVTSLQIIFATFMTAGMLILLGFVVFLRNKSNKQTPLIAECNPEYVSTVYVPDDWEVPRSQIELDGELGQGSFGMVYEGIATNVVPGEPRKKCAIKTVNENASLRERVEFLNEASVMKASNTHHVVRLIGVVSQGQPPYVVMELMANGDLKSYLRLHRPDATVEPHKQPPTLKRIRQMAIEIADGMAYLAAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMSPESLKDGVFTSSSDVWSYGVVIWEMATLASQPYQGLSNEQVLNYVKTGGCMERPDNCPDVLYNLMRQCWQHKPADRPTFMQLVRCLLPFAHPSFASLSFYHSDEGGQERRASTSTPQATVEEETPLRVTRDVEDFSLSDDEDDYEPHLPAPAPAPATDTKVSNGSATAPTPNGFIRRPPAANGNSVNVKTTKC
Protein: Rho guanine nucleotide exchange factor 1 (M0QZR4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MEDFARGAASPGPSRPGLVPVSIIGAEDEDFENELETNSEEQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPNVAFELDRTRADLISEDVQRRFVQEVVQSQQVAVGRQLEDFRSKRLMGMTPWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGLYMRHLGVRTKSGDKKSGRNFFRKKVMGNRRSDEPAKTKKGLSSILDAARWNRGEPQVPDFRHLKAEVDAEKPGATDRKGGVGMPSRDRNIGAPGQDTPGVSLHPLSLDSPDREPGADAPLELGDSSPQGPMSLESLAPPESTDEGAETERLSGRLGRSESLRVSDRRRPSRGSLGAKGRGGGRSRSDVDMDPSSATAVLGPARRATPEPGDEGEPGRSGLELEPEEPPGWRELVPPDTLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFFQPMAECLFFPLEELQNIFPSLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPTEREKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAPASRPKPRPSPSSTREPLLSSSENGNGGRETSPADARTERILSDLLPFCRPGPEGQLAATALRKVLSLKQLLFPAEEDNGAGPPRDGDGVPGGGPLSPARTQEIQENLLSLEETMKQLEELEEEFCRLRPLLSQLGGNSVPQPGCT
Protein: Blue copper protein 1a (MtBcp1a) (G7L0H3)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- GRAS family protein RAD1
- Elongation factor 1-alpha
- Inhibitor of trypsin and hageman factor-like protein
- 1-phosphatidylinositol 4-kinase
- Peroxidase
Sequence:
MASSRVVLILSISMVLLSSVAIATDHIVGDDKGWTVDFDYTQWAQDKVFRVGDNLVFNYDPARHNVFKVNGTLFQSCTFPPKNEALSTGKDIIQLKTEGRKWYVCGVADHCSARQMKLVITVLAEGAPAPSPPPSSDAHSVVSSLFGVVMAIMVAIAVIFA
Protein: HapE (C8V0B5)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcriptional activator HAP2
- Transcription factor HapC
- DNA polymerase epsilon subunit D
- BZIP domain-containing protein
- GATA-type transcription factor sreA
- ABC-transporter-regulating transcription factor
Sequence:
MEQAQQTSGQQQGRQQPVYDTRQGGHYGASAALAAQGFAPVAELYTGTWANVNQGLQGTARDILTTYWQHVINHLESDNHDYKIHQLPLARIKKVMKADPEVKMISAEAPILFAKGCDVFITELTMRAWIHAEDNKRRTLQRSDIAAALSKSDMFDFLIDIVPREEATSHAKRSSQSAGAPAGPGGPTAAGQLPQTQHGVQHHPHHMAPPDYGALGQHPLQDQEYRQQTMYGGAVQSDPTAAYAQPQTQMFEGMYTAYPHLPPQQ
Protein: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Glycine transaminase AADAT) (EC 2.6.1.4) (Kynurenine aminotransferase II) (Kynurenine--glyoxylate transaminase AADAT) (EC 2.6.1.63) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II) (Methionine--glyoxylate transaminase AADAT) (EC 2.6.1.73) (Q64602)
Organism: Rattus norvegicus (Rat)
Function: Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Kynurenine 3-monooxygenase
- Kynureninase
- Kynurenine--oxoglutarate transaminase 1
- Kynurenine formamidase
- 2-oxoadipate dehydrogenase complex component E1
- Alpha-aminoadipic semialdehyde dehydrogenase
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- Dihydrolipoyl dehydrogenase, mitochondrial
- 3-hydroxyanthranilate 3,4-dioxygenase
- Kynurenine--oxoglutarate transaminase 3
Sequence:
MNYSRFLTATSLARKTSPIRATVEIMSRAPKDIISLAPGSPNPKVFPFKSAVFTVENGSTIRFEGEMFQRALQYSSSYGIPELLSWLKQLQIKLHNPPTVNYSPNEGQMDLCITSGCQDGLCKVFEMLINPGDTVLVNEPLYSGALFAMKPLGCNFISVPSDDCGIIPEGLKKVLSQWKPEDSKDPTKRTPKFLYTIPNGNNPTGNSLTGDRKKEIYELARKYDFLIIEDDPYYFLQFTKPWEPTFLSMDVDGRVIRADSLSKVISSGLRVGFITGPKSLIQRIVLHTQISSLHPCTLSQLMISELLYQWGEEGFLAHVDRAIDFYKNQRDFILAAADKWLRGLAEWHVPKAGMFLWIKVNGISDAKKLIEEKAIEREILLVPGNSFFVDNSAPSSFFRASFSQVTPAQMDLVFQRLAQLIKDVS
Protein: SNF1-related protein kinase regulatory subunit beta-1 (AKIN subunit beta-1) (AKINB1) (AKINbeta1) (Q84VQ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulatory subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, which may play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants. The SnRK complex may also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase and in assimilation of nitrogen by phosphorylating nitrate reductase.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17827350}.
Interaction partners:
- Sucrose nonfermenting 4-like protein
- SNF1-related protein kinase regulatory subunit gamma-1
- SNF1-related protein kinase catalytic subunit alpha KIN10
- SNF1-related protein kinase catalytic subunit alpha KIN11
- Amino acid transporter AVT6D
- F-box protein At2g14290
- Rhodanese-like domain-containing protein 15, chloroplastic
- At1g72820/F3N23_2
- SNF1-related protein kinase regulatory subunit gamma-like PV42a
- At5g06430
Sequence:
MGNANGKDEDAAAGSGGADVTSSSARSNGGDPSARSRHRRPSSDSMSSSPPGSPARSPSPFLFAPQVPVAPLQRANAPPPNNIQWNQSQRVFDNPPEQGIPTIITWNQGGNDVAVEGSWDNWRSRKKLQKSGKDHSILFVLPSGIYHYKVIVDGESKYIPDLPFVADEVGNVCNILDVHNFVPENPESIVEFEAPPSPDHSYGQTLPAAEDYAKEPLAVPPQLHLTLLGTTEETAIATKPQHVVLNHVFIEQGWTPQSIVALGLTHRFESKYITVVLYKPLTR
Protein: Os08g0524800 protein (Q84QW1)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Os03g0726900 protein
Sequence:
MDGGRVGGDYISSLLSSSPRLDFGVPVLDAIVAPGGGGGGGDCGLDKLCGDPGFAERAARLSSFNNGGGGVGQRYGGAGAGLFGMPPPAPGDFAGGGSREASSVSDPASSAMKDAAANAKKRKSTAAAAAAAKGKGKEPPVGEEKESDGKRCKTGNGEKESSVKPKAEQAGSDSSVEDGGGGGQKQGKGKNAKPVEPPKDYVHVRARRGQATDSHSLAERVRRERISQRMKVLQDLVPGCNKVIGKALMLDEIINYVQSLQRQVEFLSMKLATVNPLDFSNLPTLLQKDMFQACGPSASSVFSLESSNSAFRFAEQGDVFQQFAQNSMESQCTLNQLDLALSQATNAAQYAFQDGTAGANLQQRNFWEDDLQSVFHIENGQSQENGVSAPNFHGQQQAGHMKMEF
Protein: Grunge, isoform C (Q86BH2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAASTQGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERELEESRWSPGVVADGDLLMFLRAARSMAAFQGMCDGGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVKCPVSKGIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQSALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASRSSPAVSKEENSSLTEDDASECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNNTAGNGGGNATSISSGSTGGGAAGGNSSSKDQSANAVANGKRPKRGSETPDVSGGASVDSPKTPTKAVAESSANKRKGGKQDTPNKKKRTEQESNEPSAHEENAIKEKRKRPDSPVESMNSDSRPDSVLDDGESNTTDTTTAEQQSTKDSKETVSCKEEREMVTNDLEAKAEEKAIKAEALAEDSKDSAIKNMDEETNIQAPSSADTSLVDGPNPNALPSPVAAPITMKVPTIATVEALNASVDRKEAIEKMESCDSDPEMLKKLATIKQEVSPQQQQHMQQQSQQQMQQQLAPVGIPQPPSCPPSESVYIKKEPMEDSMDATCNQNSNEPQDLKVKIEIKNEDALKHSAGGLPPSGPCAPPSALHPLSGAPVESGQEPLHLQHMPHGQVTTQPPPGYLIDGQLKYGPSGQGVPPQPPQLHSDAAGGVSGAPPGAPTTPQKYPPEMEMKFAPQDLKYPPPPPLDALKYSQEMQAAAAAAAAAGKYDMKYMMEQQGKYNVELSAAHQPPSKPGYQDSLKIPDIKPGFGHLPHNVGSPLDAAHKYGPPPTSQESQQQQPQPPAHQVPPGATPPPGIAMPKPHYQHDVQTPPLGRPFEPTGLMLKYGDPLAAKYGPPQDLKYPMPPVSQAGPADVKPYGGENLIKSSPYGPPPESPIDASARSTPGQDSQGSNSNSQPPSMPPQPQQFQSPHPSPHMPSPAGGGLPPGMHPQNLIHGPPPGAAGGSGPQPPPPPTSLHQPTPTSAGPPSLQHGLHPGHQHSQLSVASSIPPSSIGIPPTLSTMAPSHMHPHLHPHAHLQGLHRPHDLPPSMHPHAPMPLSLQGHPQHGHGLPPSHTSQQQQQQQQQQQPGGPAGTVRTPSPAQQPPRSMHDPQSSREPPTSQPSTTMAGSSGPGGPPPQQSPHAHRTSPLPGLAGSGPPPPGLIGHPMAIHPHLAHLPPGHPAHAALAHPGHHLLSHSIAGLGPGGGPIALLAGPGGLGGIPESALSRRTPPSHLPHSHASSAPLTAHSVASMTSTSMSLTTSTVPSSAFSRASPSVQISSSGGGPSGPGSVGPGGMPNSSAAAAAAAAAHRAASPASSVSSLSRQSPLHPVPQSPLSHHPSSSALSAAAAAVAERDRHALMRQQSPHMTPPPVSNASLMASPLSKMYAPQPGQRGLGTSPPPHLRPGASPPVIRHPQMPLPLPLIAPGGGIPQIGVHPGQSPYPHPLLHPSVFYSPHHHPFNSPYGYAPYGPGFPAYMKPPPQPGQLDPAAVMAAHHAGLQGPPPQQMRQDEQNAAAAAAQAAAEKQHQAAAAAAAQQHKAPQQQQPGGMPPNKPPTPKTPQGPGGGMPPGMGGPGTPTGLPPGAYPGSHMPGYPQGPPHGSPFAPQDGQPHGLKPTSHMDALRAHAHSANSAGMGGGHHPTEPLPIDIEPDPEPEIPSPTHNIPRGPSPEAKPDDTECHRSQSAIFVRHIDRGDYNSCTRTDLIFKPVADSKLARKREERDRKLAEKERERRQQQQQQQQQQQQQQAAAAQQAAQQAKMKAELKPPYADTPALRQLSEYARPHVAFSPVEQMVPYHHPMGPMYRERELEEIKNAQAAAASQSRLDPHWMEYYRRGIHPSQFPLYANPAISQMERERLGIPPPHHVGLDPGEHMVRMPQPPEAGFQLPPNVGQYPRPNMLIPREPHSDVLLRMSYADQLQYLQAAEFQRQSLHDQYFRQRPR