wanglab/gogpt-training-data huggingface dataset:
Protein: U3 small nucleolar RNA-associated protein 10 (U3 snoRNA-associated protein 10) (U three protein 10) (U3 protein 10 required for transcription) (t-UTP10) (P42945)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). Involved in ribosome biosynthesis.
Subcellular location: Nucleus, nucleolus. Mitochondrion. Note=Associated with ribosomal chromatin, even in the absence of transcription.
Interaction partners:
- U3 small nucleolar RNA-associated protein 6
- Nucleolar protein 6
- U3 small nucleolar RNA-associated protein 20
- Nucleolar protein 58
- KRR1 small subunit processome component
- U3 small nucleolar RNA-associated protein 8
- Essential nuclear protein 1
- Ribosomal RNA-processing protein 9
- NET1-associated nuclear protein 1
- 13 kDa ribonucleoprotein-associated protein
Sequence:
MSSLSDQLAQVASNNATVALDRKRRQKLHSASLIYNSKTAATQDYDFIFENASKALEELSQIEPKFAIFSRTLFSESSISLDRNVQTKEEIKDLDNAINAYLLLASSKWYLAPTLHATEWLVRRFQIHVKNTEMLLLSTLNYYQTPVFKRILSIIKLPPLFNCLSNFVRSEKPPTALTMIKLFNDMDFLKLYTSYLDQCIKHNATYTNQLLFTTCCFINVVAFNSNNDEKLNQLVPILLEISAKLLASKSKDCQIAAHTILVVFATALPLKKTIILAAMETILSNLDAKEAKHSALLTICKLFQTLKGQGNVDQLPSKIFKLFDSKFDTVSILTFLDKEDKPVCDKFITSYTRSIARYDRSKLNIILSLLKKIRLERYEVRLIITDLIYLSEILEDKSQLVELFEYFISINEDLVLKCLKSLGLTGELFEIRLTTSLFTNADVNTDIVKQLSDPVETTKKDTASFQTFLDKHSELINTTNVSMLTETGERYKKVLSLFTEAIGKGYKASSFLTSFFTTLESRITFLLRVTISPAAPTALKLISLNNIAKYINSIEKEVNIFTLVPCLICALRDASIKVRTGVKKILSLIAKRPSTKHYFLSDKLYGENVTIPMLNPKDSEAWLSGFLNEYVTENYDISRILTPKRNEKVFLMFWANQALLIPSPYAKTVLLDNLNKSPTYASSYSSLFEEFISHYLENRSSWEKSCIANKTNFEHFERSLVNLVSPKEKQSFMIDFVLSALNSDYEQLANIAAERLISIFASLNNAQKLKIVQNIVDSSSNVESSYDTVGVLQSLPLDSDIFVSILNQNSISNEMDQTDFSKRRRRRSSTSKNAFLKEEVSQLAELHLRKLTIILEALDKVRNVGSEKLLFTLLSLLSDLETLDQDGGLPVLYAQETLISCTLNTITYLKEHGCTELTNVRADILVSAIRNSASPQVQNKLLLVIGSLATLSSEVILHSVMPIFTFMGAHSIRQDDEFTTKVVERTILTVVPALIKNSKGNEKEEMEFLLLSFTTALQHVPRHRRVKLFSTLIKTLDPVKALGSFLFLIAQQYSSALVNFKIGEARILIEFIKALLVDLHVNEELSGLNDLLDIIKLLTSSKSSSEKKKSLESRVLFSNGVLNFSESEFLTFMNNTFEFINKITEETDQDYYDVRRNLRLKVYSVLLDETSDKKLIRNIREEFGTLLEGVLFFINSVELTFSCITSQENEEASDSETSLSDHTTEIKEILFKVLGNVLQILPVDEFVNAVLPLLSTSTNEDIRYHLTLVIGSKFELEGSEAIPIVNNVMKVLLDRMPLESKSVVISQVILNTMTALVSKYGKKLEGSILTQALTLATEKVSSDMTEVKISSLALITNCVQVLGVKSIAFYPKIVPPSIKLFDASLADSSNPLKEQLQVAILLLFAGLIKRIPSFLMSNILDVLHVIYFSREVDSSIRLSVISLIIENIDLKEVLKVLFRIWSTEIATSNDTVAVSLFLSTLESTVENIDKKSATSQSPIFFKLLLSLFEFRSISSFDNNTISRIEASVHEISNSYVLKMNDKVFRPLFVILVRWAFDGEGVTNAGITETERLLAFFKFFNKLQENLRGIITSYFTYLLEPVDMLLKRFISKDMENVNLRRLVINSLTSSLKFDRDEYWKSTSRFELISVSLVNQLSNIENSIGKYLVKAIGALASNNSGVDEHNQILNKLIVEHMKASCSSNEKLWAIRAMKLIYSKIGESWLVLLPQLVPVIAELLEDDDEEIEREVRTGLVKVVENVLGEPFDRYLD
Protein: Cytochrome f (P26287)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
Subcellular location: Cellular thylakoid membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Cytochrome b6
- Cytochrome b6-f complex subunit 4
- Cytochrome b6-f complex iron-sulfur subunit 2
- Cytochrome b6-f complex subunit 5
- Cytochrome b6-f complex subunit 7
- Cytochrome b6-f complex subunit 8
- Cytochrome b6-f complex iron-sulfur subunit 1
- Cytochrome b6/f complex iron-sulfur subunit
- Plastocyanin
- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Sequence:
MRNPDTLGLWTKTMVALRRFTVLAIATVSVFLITDLGLPQAASAYPFWAQETAPLTPREATGRIVCANCHLAQKAAEVEIPQAVLPDTVFEAVVKIPYDLDSQQVLGDGSKGGLNVGAVLMLPEGFKIAPPDRLSEGLKEKVGGTYFQPYREDMENVVIVGPLPGEQYQEIVFPVLSPDPAKDKSINYGKFAVHLGANRGRGQIYPTGLLSNNNAFKAPNAGTISEVNALEAGGYQLILTTADGTETVDIPAGPELIVSAGQTVEAGEFLTNNPNVGGFGQKDTEVVLQNPTRIKFLVLFLAGIMLSQILLVLKKKQIEKVQAAELNF
Protein: Heat shock 70 kDa protein BIP5 (Luminal-binding protein 5) (OsBiP5) (Q6Z058)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Functions as chaperone during endoplasmic reticulum (ER) stress response.
Subcellular location: Endoplasmic reticulum {ECO:0000255|PROSITE-ProRule:PRU10138}.
Interaction partners:
- Os02g0710900 protein
- Serine/threonine-protein kinase/endoribonuclease IRE1
- Endoplasmin homolog
- Calnexin
- DnaJ protein ERDJ2
- Co-chaperone Hsc20 family protein, expressed
- HEAT repeat family protein, expressed
- Armadillo/beta-catenin-like repeat family protein, expressed
- Os09g0512700 protein
- Os01g0616333 protein
Sequence:
MARPRRASTMQLGLFLAALLLLTPSPAGSVAAAKGGGAKSGGGGTVIGIDLGTTYSCVGVYRNGHVEIIANDQGNRITPSWVAFTDGGERLIGEAAKNQAAANPERTIYDAKRLIGRQFSDAEVQRDMKLLPFAVVDRNGKPHVRVEVKDGDVRVFSPEEVSAMVLTRMKETAEAYLGEKVTRAVVTVPAYFNDAQRQATKDAGVIAGLTVDRIINEPTAAAIAYGIDKKGAEKNVLVFDLGGGTFDVSILAIDNGVFEVLATNGDTHLGGEDFDQRLMDHFVKVIRRKHGRDITGDARALGKLRRECERAKRALSNQHQVRVEVESLFDGVDLSEPLSRARFEELNSDLFKKTMVPVRKAMADARLSKGDIDEIVLVGGSTRIPKVQQLLKDYFGGKEPNRGVNPDEAVAYGAAVQASIISGHVDENTESMILLDVAPLTLGLETAGGVMAKLIPRNTVVPTKKTQVFTTYKDKQTTVTIQVFEGERSMTRDNRLLGRFDLAGIAPAPRGAPQIEVTFEVDANGILSVLAADKATGRSEKITISGDDRKISQEEIDRMVREAEEFAEEDRRHREQVDARNSLEAYVYNIKNTLGGKMADAMEGEEKDKVEEAVREAYEWLDGNPDAGKEEYEEKLRELEDVCNPVMSAVYQRSGGGGGGAPEDGNVDDEDDHDEL
Protein: ATPase family gene 2 protein (EC 3.6.4.10) (O60058)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes. Plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein rlp24 from the pre-ribosomal particles. This step facilitates the subsequent release of other shuttling proteins such as nog1 and allows the transition of the pre-ribosomal particles to later maturation forms that bind SPCC550.15c/REI1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized protein C115.02c
- Probable metalloprotease arx1
- Ribosome biogenesis protein rlp24
- UBX domain-containing protein 3
- Nuclear protein localization protein 4
- Ubiquitin fusion degradation protein 1
- Ubiquitin conjugation factor E4
- Uncharacterized derlin-like protein C365.08c
- Ubiquitin homeostasis protein lub1
- ERAD-associated E3 ubiquitin-protein ligase hrd1
Sequence:
MSVAIKFTVKINDGSLRRQQTRHVFLSPAALNRLKLSPSQVIYLKHKGGEAVGITQSVKGNGIGPFEILISPLLAKWANLKAFQRVNISQYVHPLKEAEGIKIVASLSSNNEPIPESLIRKELLEIRYLHPGMIVMGESPMNMAKSGSKNLSSENMATEIFEINSGLSAQSGTEVGSSQSSPSVNESEPKATEDLDELSPGSYKVKEIHIRSPSNLIEAISDMSLDEPRIYKFTAASSMEIETPDLLKLPHEDRTQSAYNQGSEETQNFDGPPSAVTFSSIGGLQAQIAQIRDIVELPFQNPELFKFFNIMPPRGVLLYGPPGTGKTMVMRAVAAEANAQVFTIDGPSVVGKYLGETESRLRKIFEDARAHQPSIIFIDEIDALAPKRTEDVSEAESRAVATLLTLLDGMANAGKVVVIAATNRPNSIDEALRRPGRLEKEIEIGIPDKSARLDIIKLLLSGVPNEINDAQLEDLASRTHAYVGADLAAVVREAALRAIKRTISLQKDTSGLDIFGAVQMDDLEFALSSVRQSAMREFMMESPNVHWSDIGGQEEVKQKLKESVEWPLTHGETFSRLGVRPPKGVLLYGPPGCSKTITAKAIATETGLNFIAVKGPELFDKFVGESERAVRQVFQKARQASPSVIFFDEIDALTANRGEDNSSDRVVAALLNELDGIEALRNVLVLAATNRPDMIDPALMRPGRLDRLLYVGPPNFEARKQIVKIQAEKMKFAEDVDLDLIAEKTEGCSGAEVVALCQEAGLIAMHEDLEAKEICQAHFKTALLALRKAITRDMLEYYASFSESVTSIS
Protein: Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102) (Q62936)
Organism: Rattus norvegicus (Rat)
Function: Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
Interaction partners:
- Glutamate receptor ionotropic, NMDA 2B
- Glutamate receptor ionotropic, NMDA 2A
- Disks large homolog 4
- Disks large homolog 2
- Glutamate receptor ionotropic, NMDA 1
- Disks large homolog 1
- Ras/Rap GTPase-activating protein SynGAP
- E3 ubiquitin-protein ligase NEDD4
- Glutamate receptor ionotropic, NMDA 3A
- Glutamate receptor ionotropic, NMDA 2C
Sequence:
MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPSGGNGASSGYGGYSSQTLPSQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKNTPKLNGSGPSWWPECTCTNRDWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVTYPAPPQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
Protein: Lectin CPL (J9PBR3)
Organism: Bionia pedicellata (Camptosema pedicellatum)
Function: D-mannose/D-glucose-binding lectin that also binds derivative alpha-methyl-D-mannppyranoside. Has hemagglutinating activity towards rabbit erythrocytes.
Interaction partners:
Sequence:
ADTIVAVELDTYPNTDIGDPNYQHIGINIKSIRSKATTRWNVQDGKVGTAHISYNSVAKRLSAIVSYPGGSSATVSYDVDLNNILPEWVRVGLSASTGVYKETNTILSWSFTSKLKTNSTADAQSLHFTFNQFSQSPKDLILQGDASTDSDGNLQLTRVSNGSPQSNSVGRALYYAPVHVWDKSAVVASFDATFTFLIKSPDSDPADGIAFFIANTDSSIPHGSGGRLLGLFPDAN
Protein: Protein PLANT CADMIUM RESISTANCE 1 (AtPCR1) (Q9LQU2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in glutathione-independent cadmium resistance. Reduces cadmium uptake rather than activating efflux, but is not closely coupled to calcium transporter.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- At4g25315
- Similarity to Ta11-like non-LTR retroelement protein
- WAT1-related protein At5g40240
- U-box domain-containing protein 54
- At4g01000
- At1g07135
Sequence:
MEAQLHAKPHAQGEWSTGFCDCFSDCRNCCITLCCPCITFGQVAEIVDRGSKSCCAAGALYMLIDLITSCGRMYACFYSGKMRAQYNIKGDGCTDCLKHFCCNLCALTQQYRELKHRGFDMSLGWAGNAEKQQNQGGVAMGAPAFQGGMTR
Protein: RPTOR independent companion of MTOR, complex 2 (F1M4J0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Target of rapamycin complex subunit LST8
- Target of rapamycin complex 2 subunit MAPKAP1
- DEP domain-containing mTOR-interacting protein
- Serine/threonine-protein kinase mTOR
- Proline-rich protein 5
- Regulatory-associated protein of mTOR
- AKT1 substrate 1
- TELO2-interacting protein 1 homolog
- RAC-alpha serine/threonine-protein kinase
- Serine/threonine-protein kinase Sgk1
Sequence:
MRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTDEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYASLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKVLTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQSIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHSWDSVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFILEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPTKKHRSSSDPKGGKLSSENKTSNRRIRTFTEPSVDFNHSDDFTNISPAQKTLQLETSFVGNKHLEDTGSTPSIGDNDLKFPKSFGPENHRENTSRERLVVESSAGSHMKIRSQSFNTDTTTSGISSMSSSPSRETVAVDSTTMDTDCGSLSTVVSTKTVKTSHYLTPQANHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQSKHVPPPDDRGARTFSHDGGGLPSGTGSLVKNSFHLLRQQMSLTEIMNSVHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSSICSHSDLQDIPYSDWCEQPIHNPLEVVPSKFSGISGCSDGASQEEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAIPPNQPIVDESAES
Protein: TSC complex subunit 2 (A0A2R8Y6C9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
Protein: Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin) (Q961H1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000256|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|HAMAP-Rule:MF_03023}. Note=Predominantly cytoplasmic. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with KATNB1. {ECO:0000256|HAMAP-Rule:MF_03023}.
Interaction partners:
Sequence:
MRVEEATYRRTTREKIVLRGNTTIRTVDSTSTYLPVMSPAGSSTPPTSLSHMARMMDSLILDSLSPFGFTKITATSRPSRNASLKKSSEGGHSSTAERHRPVNNLGSNAPGGLGIGGSVPLRSKQRLPTQEVAPQPRASQTAQMPFPSQQQDNRWVSSLRRRDPELQPTLPSINSNANSSSLSQSHHGSAGNVGLAGAGAPTPAASMGTMRLGRPARASAMTAALRKSRSVERLRARKLSTNTQLNLKHKPVKKNSLDENSNSDDQDATTSLEDNSHAQSLATSHNTPKCSPKTKAKHFSPLGYEVHLVDTLEKDILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASRGSDSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEAFRRRFEKRIYIPLPNEGTRSALLKLCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRLISGRTPDQIKQIRREEVDQPITLQDFQDARLRTKKSVSADDVARFEKWMEEYGSC
Protein: Probable flavin-containing monooxygenase 1 (EC 1.14.13.-) (Q9LMA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the establishment of systemic acquired resistance (SAR). Not involved in local defense mechanisms. Confers a salicylic acid-dependent (SA) resistance to virulent pathogens such as P.syringae pv tomato and H.parasitica.
Interaction partners:
- Aminotransferase ALD1, chloroplastic
- Protein SAR DEFICIENT 4
- Isochorismate synthase 1, chloroplastic
- Proline iminopeptidase
- Protein EDS1
- 4-substituted benzoates-glutamate ligase GH3.12
- Protein SAR DEFICIENT 1
- Lipase-like PAD4
- Indoleacetaldoxime dehydratase
- Calmodulin-binding protein 60 G
Sequence:
MASNYDKLTSSRVAIIGAGVSGLAAAKNLVHHNPTVFEASDSVGGVWRSCTYETTKLQSARVDYEFSDFPWPNNRDDTTFPPYLEILDYLESYAKHFDLLKFMKFGSKVIEVRFIGDGETPQMVDLGAYGNLLPGKPVWEVAVQIGDSGDIQWHAFEFVVVCTGKYGDVPRIPAFPAKKGPEMFQGKVMHSMDYCKLEKEEASTLLSGKKVAVIGFKKSAIDLALESALANQGEGGKACTMVVRTTHWGIPHYWVWGLPFFLFYSSRASQFLHDRPNQSFLRTLFCLLFSLLRAVVSKFIESYVLWKLPLEKYGLKPNHSFEEDYASCQMAIIPENFFEEADKGMIRFKKSSKWWFYEEGIVFEDGTTLEADVVILATGYDGKKKLKAIVPEPFRTWLEFPSGVMPLYRGTIHPLIPNMGFVGYVQSSSNLHTSELRSMWLSRLVDEKFRLPSKEKMLDQFLKEMEVTRNSSRFYKRHCISTFSIQHADDMCNDMGLNPWRKSNFLLEAFSPYGSQDYRLGQEEKEDMTA
Protein: Neisserial heparin binding antigen (NHBA) (Genome-derived Neisseria antigen 2132) (GNA2132) [Cleaved into: C2 fragment] (Q7DD37)
Organism: Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Function: A major human immunogenic protein detected in patients recovering from meningitidis, where it induces bactericidal antibodies. Binds heparin and heparan sulfate proteoglycan in vitro via the Arg-rich motif. Heparin-binding to this protein protects bacteria against killing by bactericidal antibodies (serum killing). Binds to human cells via the Arg-rich region; binding may require the intact protein as protein fragments do not bind to human cells. Protein binding to human cells is abolished by treatment with heparinase III but not chondroitinase ABC. The bacteria binds a number of human extracellular sialyated and/or sulfated glycans via this protein, including chondroitin sulfate (KD=5.2 nM), heparin (KD=52 nM) and ganglioside GT3 (KD=210 nM). The recombinant protein binds DNA non-specifically.
Subcellular location: [Neisserial heparin binding antigen]: Cell outer membrane {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:20133713}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}. Cell surface {ECO:0000305|PubMed:20133713}.; SUBCELLULAR LOCATION: [C2 fragment]: Host mitochondrion {ECO:0000269|PubMed:24397470}. Note=This fragment is internalized by human cells. {ECO:0000269|PubMed:24397470, ECO:0000269|PubMed:27780200}.
Interaction partners:
Sequence:
MFKRSVIAMACIFALSACGGGGGGSPDVKSADTLSKPAAPVVSEKETEAKEDAPQAGSQGQGAPSAQGSQDMAAVSEENTGNGGAVTADNPKNEDEVAQNDMPQNAAGTDSSTPNHTPDPNMLAGNMENQATDAGESSQPANQPDMANAADGMQGDDPSAGGQNAGNTAAQGANQAGNNQAAGSSDPIPASNPAPANGGSNFGRVDLANGVLIDGPSQNITLTHCKGDSCSGNNFLDEEVQLKSEFEKLSDADKISNYKKDGKNDKFVGLVADSVQMKGINQYIIFYKPKPTSFARFRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLPGGSYALRVQGEPAKGEMLAGAAVYNGEVLHFHTENGRPYPTRGRFAAKVDFGSKSVDGIIDSGDDLHMGTQKFKAAIDGNGFKGTWTENGSGDVSGKFYGPAGEEVAGKYSYRPTDAEKGGFGVFAGKKEQD
Protein: Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9) (Q96CT2)
Organism: Homo sapiens (Human)
Interaction partners:
- Kelch repeat and BTB domain-containing protein 8
Sequence:
MSRHHSRFERDYRVGWDRREWSVNGTHGTTSICSVTSGAGGGTASSLSVRPGLLPLPVVPSRLPTPATAPAPCTTGSSEAITSLVASSASAVTTKAPGISKGDSQSQGLATSIRWGQTPINQSTPWDTDEPPSKQMRESDNPGTGPWVTTVAAGNQPTLIAHSYGVAQPPTFSPAVNVQAPVIGVTPSLPPHVGPQLPLMPGHYSLPQPPSQPLSSVVVNMPAQALYASPQPLAVSTLPGVGQVARPGPTAVGNGHMAGPLLPPPPPAQPSATLPSGAPATNGPPTTDSAHGLQMLRTIGVGKYEFTDPGHPREMLKELNQQRRAKAFTDLKIVVEGREFEVHQNVLASCSLYFKDLIQRSVQDSGQGGREKLELVLSNLQADVLELLLEFVYTGSLVIDSANAKTLLEAASKFQFHTFCKVCVSFLEKQLTASNCLGVLAMAEAMQCSELYHMAKAFALQIFPEVAAQEEILSISKDDFIAYVSNDSLNTKAEELVYETVIKWIKKDPATRTQYAAELLAVVRLPFIHPSYLLNVVDNEELIKSSEACRDLVNEAKRYHMLPHARQEMQTPRTRPRLSAGVAEVIVLVGGRQMVGMTQRSLVAVTCWNPQNNKWYPLASLPFYDREFFSVVSAGDNIYLSGGMESGVTLADVWCYMSLLDNWNLVSRMTVPRCRHNSLVYDGKIYTLGGLGVAGNVDHVERYDTITNQWEAVAPLPKAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTWSFIESPMIDNKYAPAVTLNGFVFILGGAYARATTIYDPEKGNIKAGPNMNHSRQFCSAVVLDGKIYATGGIVSSEGPALGNMEAYEPTTNTWTLLPHMPCPVFRHGCVVIKKYIQSG
Protein: Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha) (O70443)
Organism: Mus musculus (Mouse)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Subcellular location: Membrane; Lipid-anchor.
Interaction partners:
- Corticotropin-releasing factor receptor 1
- Insulin-like growth factor 1 receptor
- Metabotropic glutamate receptor 1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-5
- Guanine nucleotide-binding protein subunit beta-4
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Regulator of G-protein signaling 20
Sequence:
MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC
Protein: Receptor expression enhancing protein A, isoform R (A0A0B4LG90)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNEDKSMSASCTTLPRSSSRKSERSQGGTATGQMKTRNKSEK
Protein: Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3 homolog) (dPAPST2) (Q9VVD9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Essential for viability. Involved in glycosaminoglycan synthesis and the subsequent signaling. May be involved in hh and dpp signaling by controlling the sulfation of heparan sulfate (HS).
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:16873373}; Multi-pass membrane protein {ECO:0000269|PubMed:16873373}.
Interaction partners:
- Heparin sulfate O-sulfotransferase
Sequence:
MYIDTSASSRMTDNKGSVITINGGESAGNSPPSQRKSSTSESPPELRILCFDLTYYNRTTQFLLSCAGVFFLYILYGYLQELIFTVEGFKPYGWFLTLVQFGYYIGFGLVERRLEGYRISGGSFWNIEPEPRCIPMRTYLILAALTLGTMGLSNSSLGYLNYPTQVIFKCCKLIPVLVGSILIQGKRYGLLDFAAATCMCIGLAWFTLADSQMTPNFNLLGVAMISGALLCDAAIGNVQEKAMREFKAPSSEVVFYSYGLGFVYLFVIMLVTGNFFSGFAFCLEHPVETFGYGFLFSLSGYLGIQFVLALVRSSGAPIAATVTTARKAVTIAFSFVLFSKPFTLQYLWSGLIVVLGIYLNVYSKRNKLTLADVRQRIKQFGAKVARSPSRKFLIEV
Protein: Defensin-like protein 196 (Trypsin inhibitor ATTI-4) (Q8RYE7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Ribosomal protein L18e/L15 superfamily protein
- Ribosomal protein L31
- COX assembly mitochondrial protein
- AT5g03660/F17C15_80)
- Small ribosomal subunit protein uS17y
- Uveal autoantigen with coiled-coil/ankyrin
- At3g05070
- NADH dehydrogenase 1 beta subcomplex subunit 7
- DEK domain-containing chromatin associated protein.
- Tubulin-folding cofactor A
Sequence:
MAKMSALSIFAIFIILVLVIFEIPEIEAHDSECLKEYGGDVGFGFCAPKIFPTICYRNCQKDKGANGGKCLWGEGGKVKCLCDFCSNESFNQFISLT
Protein: X-linked lymphocyte-regulated protein 5C (Q9JJR2)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000269|PubMed:26075718}. Chromosome {ECO:0000269|PubMed:26075718}. Note=May localize to synaptonemal complexes in meiotic spermatocytes. {ECO:0000269|PubMed:26075718}.
Interaction partners:
- RIKEN cDNA 1700013H16 gene
- X-linked lymphocyte-regulated protein PM1
- MAGE family member A5
Sequence:
MSNKEQKDMKKSGKHQRVHKTLPSDDFKNSDAVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKVW