wanglab/gogpt-training-data huggingface dataset:
Protein: 60S ribosomal protein L32, putative (Q38CL1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- 60S ribosomal protein L19, putative
- 60S ribosomal protein L5, putative
- 60S ribosomal protein L35A, putative
- Ribosomal protein L37
- 60S ribosomal subunit protein L31, putative
- 60S ribosomal protein L4
- 60S ribosomal protein L7a
- 60S ribosomal protein L27, putative
- 60S ribosomal protein L29
Sequence:
MVKPFVPRNIVKKRTKKFTRHRCELFPQLSSSWRKPRGEDSPVRRRYKGQKAMPNKGYGSDRRTKYITPSGFKNFPVNNVQDLYMLLMQNRKYAGVISHTVGAKARKAIVRKAHELDVRLINGNAKLRRVDV
Protein: GLABROUS1 enhancer-binding protein-like 3 (Protein GPL3) (Storekeeper-like protein At2g36340) (Q9SJM4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor. Involved in stress responses. Plays a repressive role in cell expansion by counteracting the positive role of CPR5 in this process, but does not regulate cell proliferation or endoreduplication.
Subcellular location: Nucleus {ECO:0000269|PubMed:18162594}.
Interaction partners:
- Protein S-acyltransferase 21
- Protein BASIC PENTACYSTEINE7
- Zinc-finger homeodomain protein 3
- Protein DETOXIFICATION 39
- ORMDL family protein
- CDT1-like protein a, chloroplastic
Sequence:
MVGTKRVADSIDTNSDDTLTRNREVEVEAMLSRRKQLRTTTTRTTTTRTTPLSLSSSASKMNWSKNDELVILGGIVDYENETKLSYRSDWDALYRYIKDCVEAKFSKIQLINKVKNMKRKFTYNQGRSNHGEQLSFTNTDDDEIFKLSLIIWDKNESEYVSNENIDQAKDVPSGEPETNDVPCEEQDDRDVPCEEQERANIEIDNGVREKLDQAKDVPCVEQESEDVPCVEQERVSIEIDNGEKEKLDQTMDCEEQENTDVLCEEKGDKDVPCEEQENKDVPCEEQERVSIEIDNGEEEMSSEEDGVDEVGVMEDTLDSGISFQGLGKNGVKDKSEEDDVVELGVLQEIFKEDTFFQSLGRYQQKLLLQNLENVGVERRKELINEWKALFVDEQRLCVKKLTFAAKLANLGVSP
Protein: Heterogeneous nuclear ribonucleoprotein F (hnRNP F) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed] (Q9Z2X1)
Organism: Mus musculus (Mouse)
Function: Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000250}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Heterogeneous nuclear ribonucleoprotein H
- Serine/arginine-rich splicing factor 1
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoprotein A3
- Polypyrimidine tract-binding protein 1
- Serine/arginine-rich splicing factor 2
Sequence:
MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTREGRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLDRMRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD
Protein: Nesprin-3 (Spectrin repeat-containing, nuclear envelope family member 3) (X1WGA9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus outer membrane {ECO:0000256|ARBA:ARBA00046312}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00046312}.
Interaction partners:
- Plectin b.
- Plectin
- SUN domain-containing protein 1
- SUN domain-containing protein 2
- Zgc:152977.
- Spectrin repeat-containing, nuclear envelope 1b.
Sequence:
MTQQEQHEFRESLEEARSWMQAIQERLKQNDDTKGPRSALEVRLRETEKIHSLEPDGQVKMDRVLVASEALLRNGDEELKNQTHCKLKDLKAFYDDTLTYIIHCHSRIEWVWLHWSEYLKAHEEFGLWLEKMHRSLEPLLEMQLGLQEKLWQVDHLRVLHSDIQGQAQFLERLLDEAAALFNRTGDPSVDEQTQQGLQEAYNHIRDRAQERLTLAQKIAEEHQQYQSCVHKFQSWLVSKTEEVSRFSDVDDSTQNRLKALQDLGASIAKEELTLQHIEKLSEAVKANTSPAGAEKITQEIEELRLAWQRLRQTLLELKEELQISLDSENEYSERCKELWADLAKLRTLVQKLSGDLESRDGERTEEHMVAQWKMHTGVRNKLIAQEPSVEELKSRLKELFRFPQDSKSLSDEVLAVVKEYQSVKGRSFRLSSESETALRQILQDPLHGFSQWSQLVSQVLEASSDVTEFSHIALLVQNIEKLLKNSVQLQERLSLLQVKSDLLSAVFGQEKAEDLLGELSGDMRKRELLHSQLQQRKNRLQGLISKTKDFSNAYDSIHTKLSSIKDQFVSTDGLQPDILAKKSQADQLRVIRKDLEECEAHIIALETLVSSNPTNRTKFERLYADWRLLYKALRMKVNESEENIGEHESFHENILNMEKWLMIMKQKLDSFRGSEGEWSIDNRQHEAERALGEFPEKELQLHQTEAQGHTVLAKTSEEGKVHILQDLKRLRESWMSLHTLSLNLYRLLQTTEFQDRWADGHQQGLSSDFEEGFITGDKRPDPLLRFHHEAESTGLQELERSTEADQDLIPAIVLGSIPSPRDSEVWRRERSVLDQSLDDEVDAVTSGVNRTVNRKKMQMEMKGGGDLVGSAGWTGDWVTEHMTSSGIDELDMHGRYETEPEVAQKRMKPSQIRHDDTLTGSQGPRRPADTEAQRSQFEAWLHKQNDKLTGILSNQRSLSAKELRIRQNTLKDLRAGVVWGQSQFQKLLEDQQHRSVEDMELEELRYRWMLYKSKLKEAADLKESVGGQIQEHVRSGKASSGPGFLYRVCRVALPLQLLLLALLLLAFLLPMMDEGTSCSLANNFARSFNIMLRYDGPPPT
Protein: Copper-containing nitrite reductase (EC 1.7.2.1) (O68601)
Organism: Alcaligenes xylosoxydans xylosoxydans (Achromobacter xylosoxidans)
Subcellular location: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
Interaction partners:
Sequence:
MNALRPTLLAAALAFTMAAGTAWAQDADKLPHTKVTLVAPPQVHPHEQATKSGPKVVEFTMTIEEKKMVIDDKGTTLQAMTFNGSMPGPTLVVHEGDYVQLTLVNPATNAMPHNVDFHGATGALGGAKLTNVNPGEQATLRFKADRSGTFVYHCAPEGMVPWHVVSGMSGTLMVLPRDGLKDPQGKPLHYDRAYTIGEFDLYIPKGPDGKYKDYATLAESYGDTVQVMRTLTPSHIVFNGKVGALTGANALTAKVGETVLLIHSQANRDTRPHLIGGHGDWVWETGKFANPPQRDLETWFIRGGSAGAALYTFKQPGVYAYLNHNLIEAFELGAAGHIKVEGKWNDDLMKQIKAPAPIPR
Protein: Uncharacterized fimbrial-like protein YcbU (P75859)
Organism: Escherichia coli (strain K12)
Function: Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces.
Interaction partners:
- Probable outer membrane usher protein ElfC
- Probable fimbrial chaperone protein ElfD
- Uncharacterized fimbrial-like protein ElfG
- Fimbrial subunit ElfA
- Uncharacterized fimbrial-like protein YcbV
- Uncharacterized fimbrial chaperone YcbF
Sequence:
MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDVATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAPTLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKSTKAGATGGNATAVLYFDLVYQ
Protein: ATP-binding cassette sub-family B member 6 (EC 7.6.2.5) (ABC-type heme transporter ABCB6) (F1QCK2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004146}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}. Endosome membrane {ECO:0000256|ARBA:ARBA00004337}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004337}. Endosome, multivesicular body membrane {ECO:0000256|ARBA:ARBA00004333}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004653}. Late endosome membrane {ECO:0000256|ARBA:ARBA00004414}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004656}. Melanosome membrane {ECO:0000256|ARBA:ARBA00024320}. Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004374}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
Interaction partners:
- ATP-binding cassette, sub-family B
- Ferrochelatase
- Protoporphyrinogen oxidase
- Mitoferrin-1
- Coproporphyrinogen oxidase.
- Spalt-like transcription factor 2.
- Transmembrane protein 14C
- Uroporphyrinogen III synthase.
- Mitochondrial glutathione transporter SLC25A39
- 5-aminolevulinate synthase.
Sequence:
MVEMKSFCEAGVSMQQVWVEGGLTLCFYFTLVPSVLLTLLFLFGTLLCIWYSRYGTDMEPKFVPRSGLYRLQVGLSVLLILQALGWMVFRLSWSAELPGYVVLYGCLSMLGWIWAVVLLRLERRKVLVRDRTRGHSTVLLLYWAVAFAADNLAFVSWMSPQWWWSLETSEQQMEFAFWLVRYFCSGLLFLLGLKAPGLPRRPYMLLVNEDERDVEHGAPLLGNSDEDQSTWKDFGKKVRLLVPYMWPKGSVLLQLLVLMCLGMLGIERAINVFVPIYYKNIVNQLTDGSSWKTLAMTVCVYCLLKFLQGGGAGASGFVSNLRSFLWIRVQQYTNRVVQVRLFAHLHALSLRWHLGRRTGDVLRSIDRGTSSINSLLSYIVFSIFPTIADIVIAIVYFISNFNAWFGLIVFVCMALYLTLTIFITEWRTKYRRDMNTQDNNAKSKAVDSLLNFETVKYYNAESYEVGRFEDAILKYQVSEWKTNASLALLNQTQNLIIGLGLLTGSLLCAYFVTEGKFQVGDYVLFGTYIIQLYTPLNWFGTYYRMIQNSFIDMESMFKLFTEEEEVKDEVNAGNLYFRQGKVEFENVFFSYTQGKEILKDVSFTVLPGQTVALVGQSGSGKSTIIRLLFRFYDVQGGCIKIDGQDISKVKQSSLRAHIGVVPQDTVLFNDNIRDNIRYGRVTATDQEVEEAAIAADIHDKIIGFPDGYETQVGERGLKLSGGEKQRVAIARTILKAPQIILLDEATSALDTQTERNIQASLAKVCANRTTVVVAHRLSTIIGADVILVLRDGQIVERGRHEELLAKGGLYSDMWQKQQQAQDSDSASDSETKDRKSEKLQPQTSTTAHRGH
Protein: EWS RNA-binding protein 1 (A0A140UHY3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RCG31562, isoform CRA_c.
- ATP-dependent RNA helicase A
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Heterogeneous nuclear ribonucleoprotein A1
- TATA box binding protein
- U1 small nuclear ribonucleoprotein C
- Fli-1 proto-oncogene, ETS transcription factor
- Probable ATP-dependent RNA helicase DDX5
Sequence:
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQSTATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPAETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSSQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSLSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGLPIDPDEDSDNSAVYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPLNSMRGGMPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Protein: Condensin complex subunit 2 (Barren homolog) (CAPH homolog) (p105) (Q9Y7R3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase in processes such as DNA repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:12000964}. Cytoplasm {ECO:0000269|PubMed:12000964}. Chromosome {ECO:0000269|PubMed:12000964}. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Interaction partners:
- Condensin complex subunit 3
- Structural maintenance of chromosomes protein 4
- Structural maintenance of chromosomes protein 2
- Condensin complex subunit 1
- Aurora kinase
- Structural maintenance of chromosomes protein 3
- DNA topoisomerase 2
- Structural maintenance of chromosomes protein 5
- Structural maintenance of chromosomes protein 1
- Exosome complex protein C1739.07
Sequence:
MKRASLGGHAPVSLPSLNDDALEKKRAKENSRKQRELRRSSALHSITPRRESLNNSSPFNSSHQVPVLSNFEEWIKLATDNKINSTNTWNFALIDYFHDMSLLRDGEDINFQKASCTLDGCVKIYTSRIDSVATETGKLLSGLANDSKVLQQTEEGEDAENDDEDLQKKKERKRAQRSVKTLVKDFESIRAKKFELECSFDPLFKKMCADFDEDGAKGLLMNHLCVDQHGRIVFDSSDTVIKDLENKDVEAESQEAVVAAPIESHDTEMTNVHDNISRETLNGIYKCYFTDIDQLTICPSLQGFEFDSKGNLDVSLLKSLSDEVNMITTTSLVDNTMEKTDADAASLSSDSDGEEGHIVHALEEMAYDEENPYVDVVPKAMDESENPDFGVDTEVNMADGSTMNENYSIISTAAANGVYEYFDKSMKKNWAGPEHWRIQALRKNINNASTVFNSSNTAESSDNVSRSLSSTERKKRRELDNAIDFLQEVDVEALFTPATSSLKLPKSHWKRHNRCLLPDDYQYDSKRLLQLFLKPKMSVLPNADGEGQLQLNKALDDENDLDGIQPHGFDSDGSDNVDEGIPPYGFGDSDSPKQTPLLTPPSSSGFGDNLLLTARLAKPDMLNYAKRAKKVDVRVLKEKLWKCLDLENTIKENSINSHIEGSEMESEETNMPVKSFFSTVNQLEETYEKKELKDISTSFAFICVLHLANEHNLELTSNEDFSDVFIRPGPNLTTLEALENDV
Protein: Achromobactin transport ATP-binding protein CbrD (Q47087)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Function: Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for energy coupling to the transport system.
Subcellular location: Cell inner membrane; Peripheral membrane protein.
Interaction partners:
- Achromobactin transport system permease protein CbrB
- Achromobactin transport system permease protein CbrC
- Achromobactin-binding periplasmic protein
- Fused iron-hydroxamate transporter subunits of ABC superfamily: membrane components
- Ferrichrysobactin transporter ABC permease inner membrane component
- ABC transporter, permease protein
- Hemin ABC transporter, permease protein
- ABC-type Fe3+-siderophore transport system, permease component
- Ferrichrysobactin transporter: ABC permease inner membrane component
- Iron-hydroxamate transporter subunit periplasmic-binding component of ABC superfamily
Sequence:
MTAITSRELTLGYASQTIIDNLDIQLPKGKVSVLIGSNGCGKSTLLKSFARLLKPLKGAVILNGEDIHRQSTAAVARELAILPQMPDAPEGITVKQLVSLGRYPYQNWLQQWSEQDEAMVNQALRQTGTDMLAERPVDALSGGQRQRVWIAMTLAQDTEVVLLDEPTTFLDLAHQIEVLDLLRELNRQHGKTIIMVLHDLNLACRYADHMVAVHNRTAFAQGAPAEILDEALVKTVFNLDCRIVPDPFFHTPLCIPFGREKPQERATVA
Protein: Transposon Ty1-H Gag-Pol polyprotein (Gag-Pol-p199) (TY1A-TY1B) (Transposon Ty1 TYA-TYB polyprotein) (p190) [Cleaved into: Capsid protein (CA) (Gag-p45) (p54); Ty1 protease (PR) (EC 3.4.23.-) (Pol-p20) (p23); Integrase (IN) (Pol-p71) (p84) (p90); Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (Pol-p63) (p60)] (O13535)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
Subcellular location: Cytoplasm. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENLHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQQSNDLNIESDHDFQSDIELHPEQLRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLLMMKTWDTDRYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDPGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH
Protein: Vesicle fusion protein (B0EXK3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
Sequence:
MHDAYEPVPILEKLPLQIDCLAAWDDWLLVGTKPGHLLQYRIKXDAGTNRFEVTLEKSNKNFSKKIQQLFVVSQYKILVSLLENNIHVHDLLTFQQITVVSKAKGATLFACDLQQSESGEAKLRMCVAVKRKIQLYYWKDREFHELQGDVTAPDIPKSMAWCENSICVGFKRDYYLIRMDGRGSIKELFPTGKQLEPLVAPLADGKAAVGQDDLTVVLNEEGVCTQKCALNWTDIPVAMEHQPPYIIAVLPRYVEIRTVEPRLLVQSVELQRPRFITSAGSNVVYVASNHFVWRLVPVSIASQIRQLLQDKQFELALQLAKMKDDFDTDKRQQIHHIQNLFAFNLFCQKRFDDSMQGFAKLGTDPTHVIGLYPDLLPSDYRKQLHYPNPLPPLSGAELEKAHLALIDYLTQKRSHLVKQLNDSDPSTTSPLMEGTPTIKSRKKLLQIIDTTLLKCYLHTNVALVSPLLRLENNHCHIEESEYVLKKAHKYSELIILYEKKGLHQKALQVLLDQSTKANSPLKGHERTVQYLQRLGLENLGIIFEFSPWVLKICPEDGLKIFTEDLTEVETLPRDQVLNFLKEGFKELAIPYLEHIIHMWDETRPEFHNVLIQLYLEKVQGLMKAYLNTLPEGIPAVAAGKEKGELGEFRNKLLSFLEVSSSYEPEILISDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTRMAEEYCHGHYDPATNGNKDVYLSLLRMYLSPPDVHFLGPIKMELCEPQANLQAALNVLQLHHSKLNTTKAINLLPANTQIREIQVFLESVLEEKAGRKRFDQVLKSLLQAEFLRVQEERIFHQQVKCVITDEKTCRVCKKKIGNSAFARYPNGVVVHYFCCKDRNTCPAE
Protein: Purine nucleoside phosphorylase BT_4389 (EC 2.4.2.1) (Adenosine deaminase BT_4389) (EC 3.5.4.4) (S-methyl-5'-thioadenosine phosphorylase BT_4389) (EC 2.4.2.28) (Q89ZI8)
Organism: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
Function: Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has adenosine deaminase activity.
Interaction partners:
- Adenylate kinase
- GTPase Obg
- B3/B4 tRNA-binding domain-containing protein
- Hypoxanthine phosphoribosyltransferase
- Metalloendopeptidase
Sequence:
MISITKDKRMLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKVRRNQTLLMEGMSQIPEELVIPVQTHETNYLLIGDAYLSASSQQRQEMLHGVDALITREPGYCLCISTADCVPVLVYDKKHGAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVVACIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVPSGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK
Protein: Type II keratin Kb23 (Q6IG08)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTCGFQTGNFGCASACGPRPGRCCITAAPYRGISCYRGLSGGFGSRSVCGAFRSGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKHEEKEQIKCLNSRFAAFIDKVRFLEQQNKLLETKWQFFQNRKCCESNVEPLFEGYIETLRREAECVEADSGRLAAELNHAQEAMEGYKKRYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANAEALTQEIDFLRRLYEEETRILHAHISDTSVIVKMDNSRDLNMDCVIAEIKAQYDDIASRSRAEAESWYRTKCEEIKATVIRHGETLRRTREEINELNRIIQRLTAEIENAKCQNTKLEAAVTQSEQQGEAALTDARCKLAELEAALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGAVNVCFLAPKRRLLYTTYKLKTEAFCAIPQRAGVNKRTKGRCQQLPWWSCVRGPLCVWFKACDRQCLQCPMQRECGSEHRPVCTLWKWPLSPGEVLGVKREPSSLAYKADLGGLKVCCPSSVAAPPATCWQGACC
Protein: Phosphoglycerate kinase 1 (EC 2.7.11.1) (EC 2.7.2.3) (P09411)
Organism: Mus musculus (Mouse)
Function: Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P00558}. Mitochondrion matrix {ECO:0000250|UniProtKB:P00558}. Note=Hypoxic conditions promote mitochondrial targeting. Targeted to the mitochondrion following phosphorylation by MAPK1/ERK2, cis-trans isomerization by PIN1, and binding to mitochondrial circRNA mcPGK1. {ECO:0000250|UniProtKB:P00558}.
Interaction partners:
- Triosephosphate isomerase
- Phosphoglycerate mutase 1
- Glyceraldehyde-3-phosphate dehydrogenase
- Glucose-6-phosphate isomerase
- Alpha-enolase
- Phosphoglycerate mutase 2
- Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
- Bisphosphoglycerate mutase
- Glyceraldehyde-3-phosphate dehydrogenase
- L-lactate dehydrogenase A chain
Sequence:
MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEEEGKGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVGRAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV
Protein: Centrosomal protein of 162 kDa (Q22387)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSGIKPSVSKGESQAPQTRQLEASKPTVQGIIDILHDTISYVQVEKQSKTINFSIPHLQMIKEQLESIQLKDKNYKDLEKKFNEKQDEHLETIQKLDSTLSRQKLKYDDMRQALSVKIYTLENECSNLQDNYADLQNDFEVQIEKFKKLQNLKSIQNHENSKNVNPLTLDELTEQLKQFKEELSIDQKLKNIQLTCEGLQSAVGNFEMNSKKAKEIEILKMDIKKTQELYESRLLRAAQENKKLLRKNDTLKNYLDNQTAKIGELTAGNKTENRSPTPTLQGLIEILQKFSDDQKLEPECKMLQLHKEECRLILESLEVHDKKDQEIQWFQRQINDQKKRIANLGWSYENALEDKDALELKLEHQYEQMMELKKNFIPKNEISEDLAKTVRNFGKRLRNSRGNLKNAFKELEALKEVQEEEGSSDESSESSASDDLPDGDSSSEE
Protein: Heparan-sulfate 6-O-sulfotransferase (EC 2.8.2.-) (Q968Z7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Membrane {ECO:0000256|RuleBase:RU364122}; Single-pass type II membrane protein {ECO:0000256|RuleBase:RU364122}.
Interaction partners:
Sequence:
MEPRSKIRTIIVFCLFLAIAGIIGFGYFCQDQVCALSKRAVILQSSDILAYNELPLHQANSINGNANGNSNGNGNSVGGITAMASKSSAPQNIIANAGLSYEDVLNDDFQFDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGWKCGLHADWTELTSCVDVELDKNEGETAKRRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKLNSLDIELYAFAKTLLFQRFEHLKAKDTNFEQRYANLGNIYFKQGVTEFNWDSNVEDGLSTDH
Protein: Hairy and enhancer of split 5 (Hairy and enhancer of split-related 15, tandem duplicate 1) (Her15) (Q7T3J0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Neurogenic locus notch homolog protein 1
- Protein jagged-1a
- Notch receptor 3.
- Protein jagged-1b
- Brain-type fatty acid-binding protein
Sequence:
MAPAYMTEYSKLSNKEKHKLRKPVVEKMRRDRINNCIEQLKSMLEKEFQQQDPNAKLEKADILEMTVVFLKQQLRPKTPQNAQIEGYSQCWRETISFLSVGSEAVAQRLQQEAQRSAAPELTHTSEAPHQQHTHIKQEPRAHAPLWRPW
Protein: Transmembrane protein 31 (Q5JXX7)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MRLTEKSEGEQQLKPNNSNAPNEDQEEEIQQSEQHTPARQRTQRADTQPSRCRLPSRRTPTTSSDRTINLLEVLPWPTEWIFNPYRLPALFELYPEFLLVFKEAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILSLSFFILLVLLLLLFIIVFILIFF
Protein: GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed] (P20171)
Organism: Rattus norvegicus (Rat)
Function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19878719}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Shuttles between the plasma membrane and the Golgi apparatus (By similarity). The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form. {ECO:0000250}.
Interaction partners:
- phosphatidylinositol-4,5-bisphosphate 3-kinase
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- SOS Ras/Rac guanine nucleotide exchange factor 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
- Ral guanine nucleotide dissociation stimulator
- Proto-oncogene tyrosine-protein kinase Src
- Neurofibromin
- RAF proto-oncogene serine/threonine-protein kinase
- SOS Ras/Rho guanine nucleotide exchange factor 2
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS