wanglab/gogpt-training-data huggingface dataset:
Protein: Probable lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (Probable JmjC domain-containing histone demethylation protein 3A) (Probable [histone H3]-trimethyl-L-lysine(36) demethylase 4A) (Probable [histone H3]-trimethyl-L-lysine(9) demethylase 4A) (Q9V333)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537}.
Interaction partners:
- JmjC domain-containing histone demethylation protein 1
- Lysine-specific demethylase 3
- 2-oxoglutarate and iron-dependent oxygenase JMJD4 homolog
- Possible lysine-specific histone demethylase 1
- Histone H3
- Heterochromatin protein 1
- Jumonji C domain-containing protein 5
- Histone-lysine N-methyltransferase Su
Sequence:
MSTRSSFADEEQNKVPRIMTFRPSYEEFQNFSAYIEYIESRGAHLAGLAKIQPPAEWVPRKSGYDIDNINMTIPAPICQVVTGAHGVYQQINIQQRRQMTLRQFMEKANSELHQTPRHFDYDDLERKYWKNITYISPLYAADVKGSLSDEDLDVWNIGRLDTILNLVNTDYNIIIDGVNTAYLYFGMWKSSFAWHTEDMDLYSINYLHFGAPKTWYAIPPAYGRRLEKLANETFSENYQECNAYLRHKMTMISPKVLRQHNIPYNKITQEAGEIMITFPFGYHAGFNHGFNGAESTNFASKRWIEYGKRASICRCRSDMVKISMETFVRRFQPERYDNWLKGQDMGCHPEEPGKICAAAPPTLNEYEKQENLRAAKSEEESPQKRGCSLAGNGCERNAESAEDVDDKASVSSYSSCRQLQPVVKLRKLPTIASVPEPSSAPKRYDFNTEAVVRVKRLWNELPCPDRGANLLTNGVVKNTKRMRFQTKVLTLDDED
Protein: MitMem_reg domain-containing protein (E0AHC5)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEQLIRVYNESLVDELAHRDELDYEKEMKNSFISLLLAIQNKRRVYANDRKRKVGKASDASQLPQYLTATIPYNDHQHIDNASIASLIKILRAIHDDNTTVPTLLTDYILTHVCPKNISC
Protein: Ms4a4b protein (Q8R046)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MQGQEQTTMAVVPGVAVPSKNSVMTSQMWNEKKEKFLKGEPKVLGVLQVMIAIINLSLGIIILTTLFSELPTSVMLMVPIWGSIMFIVSGSLSIAAGVTPTKCLVCNLVCFAMEKE
Protein: Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4) (O15374)
Organism: Homo sapiens (Human)
Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Basigin
- Carbonic anhydrase 9
- E3 ubiquitin-protein ligase Hakai
- L-lactate dehydrogenase A chain
- Solute carrier family 2, facilitated glucose transporter member 1
- Hypoxia-inducible factor 1-alpha
Sequence:
MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAERWKNSLT
Protein: Protein YIPF4 (YIP1 family member 4) (Q9BSR8)
Organism: Homo sapiens (Human)
Function: Involved in the maintenance of the Golgi structure.
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:21757827, ECO:0000269|PubMed:26235900, ECO:0000269|PubMed:27999994}; Multi-pass membrane protein {ECO:0000269|PubMed:21757827}.
Interaction partners:
- Protein YIPF3
- Protein YIF1A
- Protein YIPF2
- Protein YIPF1
Sequence:
MQPPGPPPAYAPTNGDFTFVSSADAEDLSGSIASPDVKLNLGGDFIKESTATTFLRQRGYGWLLEVEDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPLIVIAPVLLVVGSFEVVSTLIKLFGVFWAAYSAASLLVGEEFKTKKPLLIYPIFLLYIYFLSLYTGV
Protein: GPI transamidase component GAB1 (Cell division control protein 91) (P41733)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- GPI transamidase component GPI17
- GPI transamidase component GPI16
- GPI transamidase component GAA1
- GPI-anchor transamidase
- GPI ethanolamine phosphate transferase 3
- GPI inositol-deacylase
- Glycosylphosphatidylinositol anchor biosynthesis protein 11
- DNA ligase 1
Sequence:
MDSTALKVALGCIAIRLAVNSLFPSLQQQLDQSVEFSTPVTSFRSLQEGIYLLRNNIQVYNHGVVHHPPILIFFLSLFNSDRLISLIYALIDGLIAYQLTEVTKAFKNLKLKVWLPGLLYAVNPLTLLSCISRSSIIFTNFAISSSLYCILAEGNVLLSSVMISISGYLSVYPILLLIPLLGMLKSWRQRILSAIVSILSLLILLLFSYSILGSQSWSFLTQVYGSIITFEKVFPNLGLWWYFFIEMFDTFIPFFKAVFNIFIAVFITPFTLRYHKQPFYAFILCIGWIVLTKPYPSLGDAGFFFSFLPFFTPLFGYLRYPIISALLFLHAIVLAPIFYHLWVVLGSGNSNFFYAISLVYALAIASILVDLNWAMLRIEYDNGIPNFKLKVTQI
Protein: Alpha-2C adrenergic receptor (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR) (Q90WY6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine > epinephrine.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Tripartite motif-containing 35-9.
- MICOS complex subunit
- Troponin I, skeletal, slow c
Sequence:
MHNLSYASEEDTYTDTDFTPSGNSTNSTSYSPATIIGLAGLVSFLILFTIVGNVLVVIAVLTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVDERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRNMSEKRRDPDGGSGTPRLENGLSREDSRRENGHCSSSPGERKPAEDNPDADLEDSSSSDEKAKRSQNETAPSKKDRRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKRRNTISRKKISQAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICREPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAFQKILCKSWKRSF
Protein: F-box protein SKP2B (F-box/LRR-repeat protein 5) (AtFB5) (SKP2-like protein 2) (AtSKP2;2) (O49286)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(SKP2B) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of the cyclin-dependent kinase inhibitor KRP1. Does not interact with auxin.
Interaction partners:
- F-box protein SKP2A
- Cyclin-dependent kinase inhibitor 7
- Transcription factor UPBEAT1
- GEM-like protein 1
- Auxin-responsive protein IAA14
Sequence:
MVSEGATRKELNLCFENMKMEGVLISEWKDIPVELLMKILNLVDDRTVIIASCICSGWRDAVSLGLTRLSLSWCKKNMNSLVLSLAPKFVKLQTLVLRQDKPQLEDNAVEAIANHCHELQDLDLSKSSKITDHSLYSLARGCTNLTKLNLSGCTSFSDTALAHLTRFCRKLKILNLCGCVEAVSDNTLQAIGENCNQLQSLNLGWCENISDDGVMSLAYGCPDLRTLDLCSCVLITDESVVALANRCIHLRSLGLYYCRNITDRAMYSLAQSGVKNKHEMWRAVKKGKFDEEGLRSLNISQCTYLTPSAVQAVCDTFPALHTCSGRHSLVMSGCLNLQSVHCACILQAHRTHTVYPHPAH
Protein: Tripartite motif containing 39 (A2AAZ6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLK
Protein: NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4) (Q9S1F9)
Organism: Psychrobacter sp. (strain TAD1)
Function: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
Interaction partners:
Sequence:
MSISKAIEKVEARYAHQPEFIQAVKEVAITIKPLYDAHPEYDKLKVFERLVEPDRVFGFRVNWEDDNGEIQINRGWRVQFSNALGPYKGGLRFHPTVNQSVLKFLGFEQIFKNALTGLPIGGGKGGSDFDPKGKTDSEIRRFCYAFMRELHHYVNKDMDVPAGDIGVGGREVSYMFAMYKNLTRESTGVITGKGVGFGGSLMRTEATGYGAVYFLQNMLAAQNESIEGKKVLVSGAGNVSLHAAEKATLIGAIVLTVSDSKGTIYDAKGLNQEKIDWLKVQKDQHKPLADYVEVFGGEWMADQKPWSIKADIAIPSATQNEINEEDAKLLVDNGVKYIVEGANMPLTAEAIDYIRLHRVHYAPGKAANAGGVAVSALEMSQNSVRQYQTFEQVDERLQGIMKDIHDSSAQASEMYGQTDEGYIDYMSGANMVGFKRVADALVAFGILN
Protein: Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) (O95672)
Organism: Homo sapiens (Human)
Function: May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
Subcellular location: Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MEPPYSLTAHYDEFQEVKYVSRCGAGGARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYEFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW
Protein: Probable GPI-anchored protein ANS1 (P38832)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
Sequence:
MKCTLVSTLFAITNILVAHAQVSNSSDTLDVQFANSTNSYIEGKFNSTDEAFNSSASWSLAAQQKKISNAAVYDVGGWNGSLYRSNRSAVADHQPGKKQDAAISQISDGQIQATASGPETTAATTPSSTANVSVYEGAGMKVESKNMGYIVGVAALLFL
Protein: Kinesin-like protein (E9QB71)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Kinesin-like protein KIF3B
- Kinesin-associated protein 3b
- Intraflagellar transport 88 homolog.
- Kinesin-associated protein 3a.
- Kinesin-like protein
- GLI family zinc finger 3.
- Kinesin-like protein
- GLI family zinc finger 2a.
- Beta-arrestin-1
- Protein smoothened
Sequence:
MPSNKLDKPEKLEVSDNVKVVVRCRPLNEKEKIMGHKQSVTVDEIRGTITVNKLDISSEPPKTFTFDTVFGPDSKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPELRGIIPNSFAHVFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQMQRLEVKERPDVGVYIKDLSGYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGNQHVRMGKLHLVDLAGSERQGKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDGSGSDDMDEDDVGDGGERRRKRRGRKKVSPDKMVEMQAKIEEERKALEAKLDMEEEERNKARAELEKREKDLLKAQQEHHLLLEKLSALEKRVIVGGVDLLAKAEEQEKLLEESNNELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHHREIEGLLENIRQLSRELRLQMLIIDNFIPQEYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVSDKKEKDPFEVDLSHVYLAYTEESMRQSLMKLERPRTSKNGKSRPKTGRRKRSSKPEAVIESLLQ
Protein: Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1) (Q8IIB8)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Pyruvate dehydrogenase E1 component subunit beta
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Dihydrolipoyl dehydrogenase, apicoplast
- Dihydrolipoyl dehydrogenase
- 3-methyl-2-oxobutanoate dehydrogenase
- Pyruvate kinase
- pyruvate kinase
- Glucose-6-phosphate isomerase
- Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase
- transketolase
Sequence:
MLLVIWLNIFWFIPYYCFNYVLCVGNKNDMLFVKNKNLIYPYNDMNRIRRHKGVELSRKMVAENIQMRNMKSNNNSNNVHENNNIDHSNNYNNNLYLSCSNKKKGKDVQSLCAIKHGNVLIKNINEEEKEKGIKKNDTDKLESKNDNEHKNEENNFVFSYDKKLNNYSEFNIYMENNNIEEYISDVNISREEICTLYEDMYLGRLFENLVAKLYYNKRVNGFVHLYNGQEAVSTGIIKNLKNSDFVTSTYRDHVHALSKGVPAHKILNELYGNYYGSTNKGKGGSMHIYSKENNFIGGFGFIGEQIPIAVGLAYSILYKNEFHYNPKNTSFTSTKNKNNYIQENENMIHMNNSQNVDVVVCFLGDGTTNIGQFFESLNLASSYNLPIIFVIENNNWAIGMESSRSSSDDLMNNYSKGKAFNIDTFKVDGNDVLTIYKLAKKKIQQIRNRTSGPIIIEAITYRAKGHSLADPDELRIKEEKTSWKKRDPILFLSSYMKKYNLVQESYFEQVKKNTQTLLQQAELDAEQNTKKGEHIDICNVIQQNIFAPSKSTPYQSEYENYKQFDDISNDELKEYYQEVLKEIQRKKEKKKLDPNDKFDQKKLPLIID
Protein: FGD5 (A0A2X0SFF2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MFRGPKPPIAPKPRLTAPNEWRASVYLNDSLNKCSNGRLPCVDRGLDEGPRSIPKCSESETDEDYIVVPRVPLREDEPKDEGSVGNKALVSPESSAEEEEEREEGGEACGLEGTGAGEDSVAPAAPGAGALSREGEEGTDLALEDEGEGCADEPGTLEQVSRSEEEEKLVQPHRECSLEDSGPWAGEGVFQSDLLLPHIHGEDQEPPDTPGEAEEDDEEGCASTDPAGADEGSGPDRPTEDMGQDAEDTSEEPPEKEELAGVQEAETATDCPEVLEEGCEEATGVTGGEQVDLSEPPDHEKKTNQEVAAATLEDHAQDESAEESCQIVPFENDCMEDFVTSLTGSPYEFFPTESTSFCSESCSPLSESAKGLESEQAPKLGLRAEENPMVGALCGQCGSLQGGAAEGPAAPDVVVVLEEEALDDALANPYVMGVGLPGQAAPGEGGQAASDALGGYGSKEELNCEAEGGLVPADRKNTSTRVRPHSGKVAGYVPETVPEETGPEAGSSAPGIGGAAEEVGKTLLSLEGKPLEASRALPAKPRAFTLYPRSFSVEGREIPVSVYQEPEGSGLDDHRIKRKEDNLSLSCVIGSSGSFSQRNHLPSSGTSTPSSMVDIPPPFDLACITKKPITKSSPSLLIESDSPDKYKKKKSSFKRFLALTFKKKTENKLHVDVNVSSSRSSSESSYHGPSRILEVDRRSLSNSPQLKSRTGKLRASESPSSLIFYRDGKRKGVPFSRTVSRVESFEDRSRPPFLPLPLTKPRSISFPSADTSDYENIPAMNSDYENIQIPPRRPARAGAFTKLFEDQSRALSTANENDGYVDMSSFNAFESKQQSADQDAESAYTEPYKVCPISSAAPKEDLTSDEEQRSSEEEDSASRDPSVTHKVEGQSRALVIAQELLSSEKAYVEMLQHLNLDFHGAVMRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCLHSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQGALSLISKVTDRANDSMEQGENLQKLVHIEHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLYTYPQKDGKYRLKNTLAVANMKVSRPVMEKVPYALKIETSESCLMLSASSCAERDEWYGCLSRALPEDYKAQALAAFHHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSGSAFSSVFQSINPSTFKKQKKVPSALTEVAASGEGSAISGYLSRCKRGKRHWKKLWFVIKGKVLYTYMASEDKVALESMPLLGFTIAPEKEEGSSEVGPIFHLYHKKTLFYSFKAEDTNSAQRWIEAMEDASVL
Protein: Scaffold protein involved in DNA repair (H0YBC9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRATK
Protein: Histone deacetylase HDT2 (HD-tuins protein 2) (Histone deacetylase 2b) (Q56WH4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:15144374}. Nucleus {ECO:0000269|PubMed:20331964}.
Interaction partners:
- Histone deacetylase 19
- Histone deacetylase 5
- Small ribosomal subunit protein eS6z
- Histone deacetylase 6
- NAD-dependent protein deacylase SRT2
- Histone deacetylase 2
- Histone deacetylase 8
- Histone deacetylase 17
- Histone deacetylase 7
- Histone deacetylase 9
Sequence:
MEFWGVAVTPKNATKVTPEEDSLVHISQASLDCTVKSGESVVLSVTVGGAKLVIGTLSQDKFPQISFDLVFDKEFELSHSGTKANVHFIGYKSPNIEQDDFTSSDDEDVPEAVPAPAPTAVTANGNAGAAVVKADTKPKAKPAEVKPAEEKPESDEEDESDDEDESEEDDDSEKGMDVDEDDSDDDEEEDSEDEEEEETPKKPEPINKKRPNESVSKTPVSGKKAKPAAAPASTPQKTEEKKKGGHTATPHPAKKGGKSPVNANQSPKSGGQSSGGNNNKKPFNSGKQFGGSNNKGSNKGKGKGRA
Protein: Alpha-1,2-fucosyltransferase (Q38FH1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSNKAFLTTNLVGGLGNQLFLVANLLATARRNGLTAVLPRMSFSSSNEQPRPVYWQSVFANLESYGVGHDLPTGVPEVIVPEQRPAAAVTLDASRQCVYNMVGFFQSETFFADHPVVSEVISPEMRRTSMRHMWENYNNGYKDPSLAHYVGLHIRRGDYLRLRDVFEILEVDYYDAAVRQLLGCALHQRSPGHRSTHLLVFCEEEERRYGASVVGYFRSKYEGLEVSLVSPTKEHVKFPCDAQMPREVLELLMLSSCDDVIMANSSWSWWAAYLNSRPVRRVVAPSRWFVQHPYPQSNHMYCNDWILL
Protein: Uncharacterized protein (G8BHG4)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Interaction partners:
- Uncharacterized protein
Sequence:
MGEIESYCNKELGPLPTKAPTLSKNVLDLFSLKGKVASVTGSSGGIGWAVAEAYAQAGADVAIWYNSHPADEKAEHLQKTYGVRSKAYKCNISDPKSVEETISQQEKDFGTIDVFVANAGVPWTEGPEINVDNYDSWNKIINLDLNGVYYCAHTVGKIFKKNGKGSLVITSSMSGTIVNVPQLQAAYNAAKAACTHLTKSLAVEWAPFARVNCVSPGYIATEISDFVEKDMKAKWWQLTPLGREGLAQELVGAYLYLASNASTYTTGANLAVDGGYTCP
Protein: Small ribosomal subunit protein mS31 (28S ribosomal protein S31, mitochondrial) (Q9VUX1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Small ribosomal subunit protein mS33
- Small ribosomal subunit protein mS40
- LD06441p
- Small ribosomal subunit protein uS3m
- 28S ribosomal protein S14
- GH07821p
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS10m
- Mitochondrial ribosomal protein S23
- Mitochondrial ribosomal protein S21, isoform A
Sequence:
MLAVRSSQRLGLRSLLPSAFKNVGLVNYSSSQSKNDDGYSSSDDEKPTKKKEEPVETAAQRLNRLLGTMQATDQLSASDFPRPGDANRKRREAQKQEAAAKNVLTAAKNIASMLGTSESDKKQTESELLAKLLGHGSESSSAATGENQTADVSGSPSGDKELNLSDIIVGMKIDRRQQPQQVEQTRGEYVRRSLASRFKPQNRDGAYQRSQRQTKREAESFTGSVNLYGGEPLGIFKDTQLPISNDILSTWSQLSERELSLQASHPPANYFEQMVLWTDQKKVWRFPINNEQDWEDEHNVDFSEHIFLEQHLEDWCPSKGPIRHFMELVCVGLSKNPYLTAQEKKDHIFWFRDYFQAKKDILRDLISKEPSKSISA
Protein: AP-3 complex subunit beta (O62348)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004145}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004145}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004145}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
Sequence:
MTSFVEGLTSPEMEIAEGGVILDNRTRFADLKAMLDSNKDNLKVDAMKRIINLIAKGKDVSELFAAVVKNVAAKNVELKKLVFVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRGSALRVLTSIRVPMVAPIMLLAIKDAVRDMSPYVRKVAAHAIPKLYSLEPELEPQLVDCIDFLLADRRSLVLGSAVYAFDEICPHRLDLLHKHFRALCRGLADVDEWGQIVMINMLTRYARHELADPDRGPPDTDVVLLLNSARPLLQSRNCSVVMAVVQLFYHVAPKAQLSQIARALVRLLRGPRETQYVVLTNIATICERNPTMFDPFLKSFFVRSCDSSLVKKLKLHVLTSLVSEANVHIILRELQTYVHMSDLASPAVEAIGRCAVRVGAVSDQCMTGLVQLISSSDEKVVCSAVVVIKRLLHASAPLNLLSRLMRLMPNMIAAQARACVIWLVATHVEQVLHMAPDFLRLIAKKFSTENELVKLEALKLAVKLWLVKRDDSEKIVQYVFQLARFDLSYDVRDRCRFLRNLMFNTEILSQHMEEIFMSKKPAPELISSFKERDKFQLGSLSHVLNQRCTKYIDLPEFPATSSDSLLRKEAHAPNELKLDDSDEEEDDDDEDEEEDEDEEEEDEDEEDEEEEENESEEEEEDDEDEESEEESDEEDEEEEEEDDSEPEEKPNPKPSTKKQALILNKSKPMNGKPKTERNDLDLLIDVDFSAAGSRQIMDATHIEEKEIELLNVIEGNGLILSISYPRINDGQYTAIRFGITNKTDGDLLGVELKTEEGLDVKGNSIIGDIPSGARVSVDLLVDFGDSATSREWILTRDDGHEKHFRFEVPYGEQVQPIRLSPEDISKERSRLGGLNRHVIQLENPINPSSIALFVNAFSSDLTIFTCQTRSRKDVCILTVSEKSIECCCDNSVIGRMLAFSVSKNC
Protein: Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2) (Q52RG8)
Organism: Rattus norvegicus (Rat)
Function: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2 (By similarity).
Subcellular location: Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Interaction partners:
- Tyrosine-protein phosphatase non-receptor type 11
- Fibroblast growth factor receptor
- Growth factor receptor-bound protein 2
- Adapter molecule crk
- Fibroblast growth factor receptor 1
- Tyrosine-protein kinase receptor
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor
- High affinity nerve growth factor receptor
Sequence:
MGSCCSCLDRDSVPHNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHQQEAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVTEEPVIITRNSHPQELDLPRGSSQPTGYTVSSFSNGFPGCPGEGPRFSSAPRRPSTSSLRHPSPGEESTQTLIASDEQSHTYVNTPTGEEDRRSRHCLQPLPEGRVPFPPQTQVSDQRDPQVFLQPGQVKFVLGPTPARRQVMKCQSLCPSMQDPPLHNNNEGPSECPAQPKCTYENVSGGLQQGAGWRLSPEERGWSGLAHRRAALLHYENLPPLPPVWESQVQQLRGEAGDDGDSKDGLTPSSNGFPDGEEDETPLQKPTSTRASARSHSSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGTAHPKGPQNPSVSGAPGPTPHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTVRKTRHNSTDLPL
Protein: Copine 1 (HCG38213, isoform CRA_b) (B0QZ18)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKMMHMAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAVPAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQA
Protein: MOSC domain-containing protein (O45394)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MLEIDKDKKVLIGCLAGSFLFYHTARQIYSYMSVKPREWVPVGVVKSLHIFPIKSCKSVDVFAFKCTKLGPVMGDLEDRAFMLVEESTGKFITARQKPKLVHVENYMTDGMLEVTVPGQPKLSVDLRKVLQNKRTIRATLFKNLKQDGYDCGDEVAKLLSDYIEEPNYRLIFYKEGLYTERTVIPDDQWWNNPVPKRNDDSGFTDLAPFHIATDASLKVLNEKLDNKITMRYFRPSIYIEGCAAWDEDKWAEIRIGDAHLECFAPCTRCVLTTVDPVKGEMSKEMQPLKKLREFRLVPDGKMRKVHMESPVFGVYAGLVNEGYIHTGQTVYVRYKPTAF
Protein: Type IV secretion system protein, VirB6 family (Q2GGX1)
Organism: Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Type IV secretion system protein,VirB6 family
- Type IV secretion system protein VirB6
- Type IV secretion system protein VirB3
- Type IV secretion system protein VirB9
- Type IV secretion system protein VirB8
- Type IV secretion system protein virB4
- Type IV secretion system protein VirB4
- Type IV secretion system protein VirB10
- Type IV secretion system protein,VirB6 family
- HigA2-like helix-turn-helix domain-containing protein
Sequence:
MFKIVLIISIFLLSSCGYHGCIKPQSVLFDEYSTTVEAGLEDGKKEHVAWVKSDLVLAGRQFLTIKVDTVNVNFCNNTKDVVNIFSSEGSTLDSSAKKFPVNIPNIMKGEKLNFRLSPALKFTVDKDICKNNNPKVYVQNTSKCMEDYLDTEYYIPVDNYDFQMNNLMYLKDRGSANKDKEKSWINFPLKILYHLDRKTYRDVSQMNISKLSSDRYQNNNDLFYLCVTDKRLNEYVTKIVEDMLNKTSSGNTAYSGDKKEQLISEKKESLLRKRDAVRKKYQKLYDAYTVNMLCGNLCNIPGYDKQKLDKNCFVVETNNMLNSCTIEKSGISGCNLNEAGQYSTVLPFLYLTHDSGITNFITVDDAVKKWQADNNSSSDIGLLTNHQYSISKDLDKNLYLELRVKDDLELIGKYTIEVTKDCSNHVKDSLYYTISKGPPTVKPGEQGTTPLNFINNEDTIVKLTGNDEVGELYFGVKDNGDGYENNTGYFNITVIAKKKIPKVISYMVERLKDSLERGLYGTSSTNSGGVNIIYNSIIENMHFIKIVNSLLVLYILMNALFYCAGFSKASIFELLTITLKISIIIYVIGPNSWDFFNNHLFKLFTEAPIQLISIMTGQDPDTSTSFEFLDIILYRFSLSESWLQILALLFAGPVGWVSVVLIFWGLVVLFLTIATAVITYLISIILIGLLLSIAPFFIICILFRRTKAIFDSWIKSLVQTAMQPVIIFASFALLTQVIDNIIYAMFNFESCDVCVLRPEFDIGITTIGFCLLEFLLPLGFSPVSVFTDNVRDSVNSDTVMFIGLPMPIVNILIFVIMANATKHFVGSSGEMCTSIFGSFANLSMVAEGAKESALGIIGMDQNSRMQRSRYQQMNEMNNQDSDGERRRDPLDLHSPSRSDDSTNRTSRGGVSIPENPPSSFGR