wanglab/gogpt-training-data huggingface dataset:
Protein: DDRGK domain-containing protein 1 (Q6P0E5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, which plays a key role in reticulophagy (also called ER-phagy) (By similarity). In response to endoplasmic reticulum stress, promotes recruitment of the E3 ufm1-protein ligase ufl1 to the endoplasmic reticulum membrane, leading to ufmylation of target proteins and subsequent reticulophagy of endoplasmic reticulum sheets (By similarity). Plays a role in cartilage development through sox9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q96HY6}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q96HY6}.
Interaction partners:
- CDK5 regulatory subunit-associated protein 3.
- E3 UFM1-protein ligase 1
- Leucine zipper putative tumor suppressor 3
- Ubiquitin-fold modifier 1
- Ubiquitin-fold modifier-conjugating enzyme 1
- Threonine synthase-like 2
- Zinc finger protein 366.
- Ubiquitin-like modifier-activating enzyme 5
- Receptor-type tyrosine-protein phosphatase alpha
- Zinc finger protein 367
Sequence:
MDVVLYIAAAAILLVLIVFSVKIRGRTQDADVEDHQNVTARVSARPQAAPERAAGMPRRRRGLHSRVNAQRAQRASDNEDSPVEADEDEEGRNASEERPQAAGKVGAKKQRKLEEKQARKAQREAEQEEREERKRLQELRDQERQKEEEKERQQEQKQEEELQRVKEEQERREEEEYQRLKESFIIEDQGEAEELTEHESQSLLQEFIQYVQKSKVVLLEDLASQFGLRTQDAIARLQDLIADGSLTGVIDDRGKFIFITPEELNAVAQFIKQRGRVSISELAQASNTLINLTPDIHSSA
Protein: Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase) (P9WMP5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
Interaction partners:
- Porphobilinogen deaminase
- Probable uroporphyrin-III C-methyltransferase HemD
- Glutamate-1-semialdehyde 2,1-aminomutase
- Glutamyl-tRNA reductase
- Possible transmembrane protein
- Possible conserved transmembrane protein
- uroporphyrinogen-III C-methyltransferase
- Uroporphyrinogen decarboxylase
- Possible transcriptional regulatory protein
- Uncharacterized protein Rv0508
Sequence:
MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHTRDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATVLMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVAAIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREIELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAAVLESLTGIRRAGADIVLTYWAVDAAGWLT
Protein: Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP) (Q8N264)
Organism: Homo sapiens (Human)
Function: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
Subcellular location: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, focal adhesion. Cell projection. Note=Localizes to actin stress fibers. In migrating cells, localizes to membrane lamellae and protusions.
Interaction partners:
- Filamin-A
- Cell division control protein 42 homolog
- Transforming protein RhoA
- Sodium channel protein type 10 subunit alpha
Sequence:
MEENNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVSEHPCNEENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ
Protein: Homeobox protein Six3 (Q9ET75)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MVFRSPLDLYSSHFLLPNFADSHHCSLLLASSGGGSGAGGGGGAGGGGGGGGGNRAGGGGAGGAGGGGGGGGGGSRAPPEELSMFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGPSGMRSLAEPGCPTHGSAESPSTAASPTTSVSSLTERADTGTSILSVTSSDSECDV
Protein: Prion-like-(Q/N-rich)-domain-bearing protein (Q21793)
Organism: Caenorhabditis elegans
Interaction partners:
- Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein
- Kynureninase
- Zasp-like motif domain-containing protein
- Ubiquinone biosynthesis O-methyltransferase, mitochondrial
- Phytoene synthase
- Cholesterol 7-desaturase
- 4-hydroxybenzoate polyprenyltransferase, mitochondrial
- 2Fe-2S ferredoxin-type domain-containing protein
Sequence:
MAEKINMSLDEIIKHGQKKVKSERVSAPAGASTSNKAGNKPTRPGNAGRNNRRVPPRKSAQVVLANKVLKKSKAIAARRAAGGQKRVFGARGKPAAAAGLSAVATKKLVNKLVKNALRKRTNITTVPVVRKRGGVAASTLAARRNFALKRNVTAAQVIQPVRTIIQQRPITAPVRTIVQHVRQAPVKVVRQIITAPVQSQVIRRAPQQQVRQNRPQQRRNVIIQSQQSRRFRPTNNNNNNRPTVIRRQVVQQVPRRAQVQRPQYEQVVQRVIQTPVAQQRFQRQPQRFQQQQPRFQQQPPRFQRQQQPQQQQVVRSVRYVNARPPVQRNNVVRQVQPVQYRPVQYVTDQVVNSRGRGFRAF
Protein: Cell division cycle 23 L homeolog (MGC69122 protein) (Q7T0N9)
Organism: Xenopus laevis (African clawed frog)
Interaction partners:
Sequence:
MAATIGMFSDLKEIKRQLLSVTWLCRERGLMNSVKWASELAFSLESVPLNELPSTPALTEEDAQDLDAYMLAKSYFDLKEYDRAAYFLRGCKSQKAYFMYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALREVRVELSKKHKARELDGFGLYLYGVVLRKLDLAKEALDVFVEATHVLPLHWGTWLELCNLITDKEMLKFLSLPDSWIKEFFLAHIYTELQLIEEALQKYQSLIDAGFSKSTYIISQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRGLKPELSYLAHNLCDIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLNESEQAAQCYIKYIQDIYSCGEIVEHQEVSTAFRYLAQYYFKCKLWDEASACAQKCFNFNDTREEGKALLRQILQLRNQSESPSAEPATAPFFLPQSLSANNTPTRRVSPLNLSSVTP
Protein: Phosphatidylcholine synthase (PC synthase) (PCS) (EC 2.7.8.24) (CDP-diglyceride-choline O-phosphatidyltransferase) (O51265)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:Q9KJY8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9KJY8}.
Interaction partners:
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
- Inner membrane protein BB_0250
- Oligoendopeptidase F homolog
Sequence:
MKNINLILAWLVHIFTASGLIVGLYSIISIVNGNYSLLLKLTVIGLIIDGIDGTMARKLKVKELIPEIDGTLLDNITDYINYTFIPVIFFYLGEFIEEKYKVAICIGILLSSAYQFSRTDAKTNDNYFRGFPSLWNLFVILNIIFKMEQITNLITMSICIITSFIPIKFIYPSKTKELRKITIPITIISCLIFVVSIFSELSTTALKMAKTVLILYFAYLTLASIYLTYKTRNR
Protein: Hydrogenase assembly chaperone hypC/hupF (Q72AR8)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Hydrogenase expression/formation protein HypD
- Hydrogenase expression/formation protein HypE
- Hydrogenase accessory protein HypB
- Carbamoyltransferase
- Hydrogenase maturation factor HypA 2
- Hydrogenase expression/formation protein HupD
- Hydrogenase expression/formation protein, putative
- Lipase, GDSL family
- Gamma-glutamylcyclotransferase AIG2-like domain-containing protein
Sequence:
MCLAIPAEIVEMMDNDMVRARVGKSETFLTVSAMLLPEPAALGDYIIVHAGFALRKLDKADAEETLRLLREVAEAAEGAPAAF
Protein: RE53824p (Q86PD1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSNSAPGSESGLAKVATPSPSPLAKLDADFTSSKFEMHPSLSDEERRFYLKMYPNVDLVNQRKVHCTVCKLHLGTAPAAESNIKMHPILRVTHCVKCHDFYNSGEFSKGEDGSELYCRWCGQGGEVYCCSTCPYVFYKSCIVKNLSKGVIVDIEQNENWNCFSCTSKILWPLRAQHWALVNYLQTQKRALQTLQLPEVEARRQMLKDNSNCCRLAKSKTSSLSDSMESLESNVSKRSQGSSAGSSKRGSMPKTIPPGPPSKRAKASNNEVVCTPDLLSMLEPDCQLSVTPKPTGRQTVTAANITTPRIVTVQQNYQPGQSSSNSGSNGSVSGSSSVPPTRSSLPPPLVLSGSGIRYRQNAPGGVSGVVRRTVVPNSVKTTGPVFHTINGFKVDLNSAAQQDSYRLPNGRLIQVKRQVPQTIQPASTVPTPPTPPALVVPQVGPGVVIRPRAPITTNRPSLHISTYGSNMGIYNPQTNQQQRAPQVRVGNANPAPPPLQGLPPNANGGQTLMITPAPQPAPKVPTLVRLTFPNTPMGQARAQLQEQIFSAMDICTHLTGKVVSLTHSNAYNQVRSYLELKELYIHMSYLMTYAIGRFKNLQEKCLVDMREKGFKNDANSLENGQLAADKQASDDEDNEIEIVEPKTDTITIDSDNEDDMPSTSTATQQEQPQETAIMKITSVTSEASKKELQENNQADIDVAAFSSTILASLLEVEVNEGASEPKPVSPGQKKQPRKKTTNKPNPALLQLERQRMEDMKKSDAKLKMKVMVKLKRAEDEFEVARKWVEDMKQGQELATKIKDSKAATPSNKTQKPSENLKISEKGSSAKKESTKQHGEGDKENTKNKEKIGDILKAAIKAKIGENEKLMAEDVQLPVDELLTEKDKELDKETLTSTEPETNKKSGTEKGSDKKQHLTKENNVKGESKDESKTDQKSDCKKGPDSECTEIEEETEMLSEKGYGGSEKEQGDTENMEDETSSERPTLIGEIEKNLLKEGKEESSEKFDKEVEPSKDVGKDSPTTQGKGQDSDKLKNARAGLKNSTQDASNTVEPPVAASNENDQSSVGELIERMDVTELDEKPKELLDCALDEVIPMEGIELSDDTEDLIKALGSPSVLPSQNTKDNETDLDANGFIGNLPLETTEPPEILLKEDECKVEKTTGISQVGAPSPAENGDTEMESTLEASDSAPDEFATAKIVG
Protein: SET and MYND domain-containing protein 4 (EC 2.1.1.-) (Q08C84)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8BTK5}. Cytoplasm {ECO:0000250|UniProtKB:Q8BTK5}.
Interaction partners:
- Protein-lysine N-trimethyltransferase SMYD5
- SET and MYND domain-containing 3.
- PR domain zinc finger protein 4
- PR/SET domain 15.
- Reticulon 4 receptor-like 1b.
Sequence:
MDLPCQDWVCHVEQKWAELRSEETERFSLLTDIDAIFNYGLSLICPEDLNILSRISEKFSVKKSPETASEFRQQGNLSFKVKDYPAAVLHYSKGVCHADKNTDELSLCYANRSAALFYQGLYQACLEDIRRSLEAGYPSHLQDKLQTRQTACQNQLRKAEKPNIPHTDHQLSPCQKTVNSTGHLSDGVSVYFSSDKGRHMLVMENKPAGEVVLEDEAYCSVLIPANIFNTGTNKAVETFGTEDRHCHHCLSQSLSFVPCPKCSYARYCGESCQKDAWDQWHQWECPVGADLLAIGVLGHLALRVVLKAGQTEVQMGIKNTKDHVTTYKNDSPVQLSLGGDCGKSLDHTDCFHGSSYMGIYSLLPHVAQHSPASRFLMAITMAVIYGKLQGGPPPNKWMSFKDEGVKASWQPEMSMLGATALRHMMQLRCNAQAITAVRVKEESGMAVQSSSEIRIATAIFPVLSLLNHSCSPNTSISFTTGFQPDPHNQLGCSEGHFDHPKGSRSGVTVTVRASKDLTAGQEILHCYGPHRSRMEVKERQRLLLEQYFFQCVCQACQRDLSEGSPNAKEHTAPGMKCVKCGKPLQSHTDGYTCSWSSCGHQISSADVQNRLQGFQLLLDEAVHLMEQDRLNEALHILQSAFSQANSILTETHPFQGELADALARLYASTGEWSLAASHLKRSLVAIQAQFGEDSIELGRQLFKLAQLHFNGRDGVASLSVIPRARRLLSLHCSPRCEELQELSEMEHCLQGLL
Protein: MIP14975p (Nuclear transport factor-2, isoform C) (D0Z726)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369002}. Nucleus {ECO:0000256|RuleBase:RU369002}.
Interaction partners:
Sequence:
MTFEGHQIQGAPKILEKVQSLSFQKITRVITTVDSQPTFDGGVLINVLGRLQCDDDPPHAFSQVFFLKANAGTFFVAHDIFRLNIHNSA
Protein: LIM/homeobox protein Lhx3 (LIM homeobox protein 3) (Q9UBR4)
Organism: Homo sapiens (Human)
Function: Transcription factor. Recognizes and binds to the consensus sequence motif 5'-AATTAATTA-3' in the regulatory elements of target genes, such as glycoprotein hormones alpha chain CGA and visual system homeobox CHX10, positively modulating transcription; transcription can be co-activated by LDB2. Synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1 (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- LIM domain-binding protein 1
- Insulin gene enhancer protein ISL-1
- Insulin gene enhancer protein ISL-2
- LIM domain-binding protein 2
- Neurogenin-2
- Pituitary-specific positive transcription factor 1
- Single-stranded DNA-binding protein 3
- LIM/homeobox protein Lhx4
- Homeobox protein ESX1
- E3 ubiquitin-protein ligase RLIM
Sequence:
MLLETGLERDRARPGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
Protein: Cyclo(L-tyrosyl-L-tyrosyl) synthase (EC 2.3.2.21) (Cyclodipeptide synthase) (CDPS) (Cyclodityrosine synthase) (P9WPF9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the biosynthesis of mycocyclosin. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L-tyrosyl-tRNA(Tyr). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides. Cyclodipeptides synthesized by Rv2275 always contain L-tyrosine.
Interaction partners:
- Mycocyclosin synthase
- Methyltransferase type 12 domain-containing protein
- Esterase Rv1288
- UPF0182 protein Rv0064
- Ribonuclease VapC24
- PE-PGRS family protein PE_PGRS28
- PE-PGRS family protein PE_PGRS43
- PPE family protein PPE8
- PPE family protein PPE56
- Phosphatase Rv3376
Sequence:
MSYVAAEPGVLISPTDDLQSPRSAPAAHDENADGITGGTRDDSAPNSRFQLGRRIPEATAQEGFLVRPFTQQCQIIHTEGDHAVIGVSPGNSYFSRQRLRDLGLWGLTNFDRVDFVYTDVHVAESYEALGDSAIEARRKAVKNIRGVRAKITTTVNELDPAGARLCVRPMSEFQSNEAYRELHADLLTRLKDDEDLRAVCQDLVRRFLSTKVGPRQGATATQEQVCMDYICAEAPLFLDTPAILGVPSSLNCYHQSLPLAEMLYARGSGLRASRNQGHAIVTPDGSPAE
Protein: JAB1/MPN/MOV34 metalloenzyme domain-containing protein (Q4Q9T0)
Organism: Leishmania major
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit 7-like protein
- CSN8/PSMD8/EIF3K domain-containing protein
- JAB1/MPN/MOV34 metalloenzyme domain-containing protein
- Eukaryotic translation initiation factor 3 subunit E
- Uncharacterized protein
- Putative eukaryotic translation initiation factor 3 subunit 8
- Eukaryotic translation initiation factor 3 subunit L
Sequence:
MSSEVAIQLTPYPAAFIIEHAKRKKYAAGYILGTVRAEEIVITDFIPHTHKDTEVPNTKAHRAELTRRRAAKRRYTTQDLIGWYSAGQPGADLTEEDYQLWCNAPSVIFQGRHCLHLHCEMPHEDGTTPKVTWTASVVFEDPADRTLKHIDHRVTLAPMNNLASDVMLSHITSLVLYNGGRPFPRSKLQNLDEVAYVASIDHKSSTDAVDEEQRRLERAVAAAQEIVTGGSGGGKEEHEMMTAVENFRAIRDEALKRQRDQTGRMDFNSQQFKDALMIKCAATILRREIDQIEHLSTVYGEDAARRGNATGGENNEKQQQPEKQQQ
Protein: Onanonoxo-7-onima-8-eninoihtemlysoneda (EC 2.6.1.62) (Q4WD65)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Acetylglutamate kinase, putative
- biotin synthase
- Aminotransferase, putative
- Aminotransferase, putative
- argininosuccinate lyase
- Arginine biosynthesis bifunctional protein ArgJ
- Ornithine carbamoyltransferase, mitochondrial
- Argininosuccinate synthase
- Amino-acid acetyltransferase, mitochondrial
- GPI anchored protein
Sequence:
MPPVRAALWRTLRAHQVYGANTDVGKTIVSTILCNAVQRRRAEKAAFLKPVSTGPLDEADDRHIQRHAAGALTKCLHQFDEPVSPHIAAQKKNLVIPRDDEILGSVHKTLSEWARTGVTFALVETAGGVHSPGPNGSSQADLYRPLRLPVVLVADSRLGGISSSISAYESLLLRGYDVNSVLLFRDDYYKNHEYLGNYFRNKSIPLVPLPQPPKRPSSQDAASLARDEEAMAGYYQRVAQESDVQGLLDELAVRNAERLDRLESMASRAHHTIWYPFTQHHGMTAKDITVIDSAHGDYFQTFESSGNADQGNLQPTFDGSASWWTQGLGHGNPELALSAAYAAGRYGHVMFAGNVHEPALSLAELLKDTLGNPRLQKVFYTDNGSTGMEVAVKMGLRAACHRYGWDASKEQISILGLKGSYHGDTIGVMDCSEPSTYNQKVEWYRGRGYWFDFPLVKLSQGTWKVEIPKELRDALGEDLEFSSLNSVFDLETRVRSEVGQRYRDFIRTTIEDLVHKQGMKFGSLIMEPIILGAGGMLFCDPLFQRCLADVVRGHPELFTNNPTAANSVGSETSWSGLPIIFDEVFTGLYRLGRKSAASFLNVHPDVAVNAKLLTGGLVPLCTTLASEEIFQAFSSPEKSDALLHGHSYTAHAVGCTVAVDSLRAMTKMESSGSWDAYRGDWKAVDVSGEDNSPEVWSVWSRDLLRDLSYADSVESVFALGTVLSISLRDAQGGGKFSHEDHFSPDSSRLTCDLVPTTLGYTSTAAKGLQQRLSAGGPQFNVHSRVLGNVLYLMSSITSKPETVRGLEELLRSALL
Protein: Very low density lipoprotein receptor (H0Z4W1)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Reelin
- DAB adaptor protein 1
- Proprotein convertase subtilisin/kexin type 9
- Hepatic triacylglycerol lipase
- Low density lipoprotein receptor adaptor protein 1
Sequence:
RAGANARASRRIGALLWRGKRSAWEARRVKGARAKCEESQFACGNGRCIPQIWKCDGDEDCLDGSDESACVKKTCAESDFVCLSGQCVPNRWQCDGDPDCEDGSDESSELCHTRTCRVNEISCGPQSTQCIPVSWKCDGEKDCDSEEDEQNCGNVTCSPADFTCSSGQCISKSFVCNGQDDCSDGSDELECAPPTCGVHEFQCKTSTCIPLSWVCDDDADCSDHSDESLEQCGRQPAPSVKCSASEVQCGSGECIHKKWRCDGDPDCKDGSDEINCPSRTCRPDQFRCEDGNCIHGSRQCNGVRDCLDGTDEANCNNVIQCSGPGKFKCRSGECIDINKVCNQQRDCKDWSDEPLKECNINECLLNNGGCSHICRDLVIGYECDCPAGFELLDRRTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKEYIQLVEQLRNSIALDADIAEQKLYWADFSQKAIFSASIDTRDKVGTHIRILDNIHSPAGIAVDWVYKNIYWSDSTAKTISVASLDGTKRKVLFLSELREPASIAVDPLSGFMYWSDWGEPAKIEKAGMNGFDRQQLVTTEIQWPNGIALDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSHMFLPHPLALTIFEDRVYWIDGENEAVYGANKFTGNDLVTLVNNLNDAQDIIVYHELVQPSGRNWCEEHMANGGCSYLCLPAPQINEHSPKYTCACPAGYFLQEDGLRCTGFNTSGTTSEVTAAGRTSAAWIILPAVLLMMAAAAGYFMWRNWQHKNMKSMNFDNPVYLKTTEEDLTIDIGRHSGSVGHTYPAISVVSTDDDMA
Protein: Ribosome biogenesis protein ytm1 (Q9URY0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Subcellular location: Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03029}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03029}.
Interaction partners:
- Pescadillo homolog
- Ribosome biogenesis protein erb1
- Ribosome biogenesis protein nsa1
- Ribosome biogenesis protein brx1
- 60S ribosome subunit biogenesis protein nip7
- Ribosome biogenesis protein rlp24
- Eukaryotic translation initiation factor 6
- Ribosome biogenesis protein nsa2
- ATP-dependent RNA helicase has1
- Probable nucleolar GTP-binding protein 1
Sequence:
MDAQSAPSGQVQVRFTTRNEDLAVGDTPIFVPTSLKRYGLSQIVNHLLKTEKPTPFDFLVQGQLLKTTLDEYIVQNGLSTESILDIEYIQSTLPPAYLASFSHDDWISGIQLTSDTILTSSYDGIARVWDKSGEIKFQSTGCGSSLKSASWHIPNQSFLTASLDQKIFHWVIEEPESMLDAEKKSSGILQTLFVGHKDIVERVRSLESSSVFISASADNTVGIWDFERSPETTLESFSSSISKKRRRKNAEFTPQAGARSPLILCEGHTGPVMDIVFSDDPSVAYSVGQDHTIKTWDLITGQNVDSKITKAPLLCVEKLTDLHLVICGSSARHIVVHDPRAGSDKIVSHTLSGHKNLVSGLSASPENPYMFASVSHDNTCRVWDVRATSGSIYTISRAEKTGSQWDKLFAVDWNKSIGIVTGGTDKQLQINQSSSFGKSE
Protein: Fragile X messenger ribonucleoprotein 1 homolog (XtFmrp) (Q6GLC9)
Organism: Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Function: Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q06787}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q06787}. Chromosome, centromere {ECO:0000250|UniProtKB:P35922}. Chromosome {ECO:0000250|UniProtKB:P35922}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q06787}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000250|UniProtKB:Q06787}. Perikaryon {ECO:0000250|UniProtKB:Q06787}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q06787}. Cell projection, axon {ECO:0000250|UniProtKB:P35922}. Cell projection, dendrite {ECO:0000250|UniProtKB:P35922}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:P35922}. Synapse, synaptosome {ECO:0000250|UniProtKB:P35922}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q06787}. Cell projection, filopodium tip {ECO:0000250|UniProtKB:P35922}. Synapse {ECO:0000250|UniProtKB:P35922}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:P35922}. Presynaptic cell membrane {ECO:0000250|UniProtKB:P35922}. Cell membrane {ECO:0000250|UniProtKB:P35922}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q06787}.
Interaction partners:
- Cytoplasmic FMR1-interacting protein
- Cytoplasmic FMR1-interacting protein
- RNA-binding protein fxr1
- Protein argonaute-2
- F-box protein 43.
- Endoribonuclease Dicer
- Phosphoinositide 3-kinase adapter protein 1
- Tudor domain-containing protein 3
Sequence:
MEELAVEVRGSNGAFYKAFVKDVHEDSITVTFENNWQQERQIPFHDVRFPPPSGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKNSFHKVKLDVPEDLRQMCAKDSAHKDFKKAVGAFSVSYDSENYQLVILSVNEVTIKRANMLSDMHFRSLRTKLSLMLRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQEAVKKARTYLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENDKNISPEEGMVPFVFVGTKDSITNATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRPDKEKGYQSEDLSGTGRGSRPYNNRGRSRRGTGYASDIRYGDPDYRKTTYPEYPRSQAFWIKGTNSEASNASETESDHRDELSDWSLAPAEDDRDNYHRRGDGRRRGGPRGQGMRGRGGFKGNDDQPRPDNRQRNSRETKARTSDGSLQIRIDCNNERSVHTKTLQNASVEGSRLRTGKDRVQKKEKSEVVDGPQVVVNGIP
Protein: LD24604p (Q8T064)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGEASGSSDFGSRGGRYRDHEDAEMEEFKPQIKVEVEDDDLERVLAKARKLKQKENIIKKPLPVDFESIQREIKPEHVEDTASGVVLTGVDGNIVLNATAEFCRTLGDIPTYGMAGNRNEDSNDMMDFDKTEQPEEHMETHTDEPALSHGTWNSVNPDEVMQPADLDNLGEDLEDRAILDEEPDVGAGVANALRLALSKGYLEKEEKNRPSNTKMAHLQAKNYSIEDKAAGEDEKVGRRDRFHFGPITDFKDKETFKPNVKLDYIDDNGRILNLKEAFRYLSHKFHGKGPGKNKIEKRLKKMEQDGLMKTMSSTDTPLGTLTMLQQKQKETKTAYVVLSGNNKNVPGVSGSAIAKFK
Protein: Prolargin (Proline-arginine-rich end leucine-rich repeat protein) (Q9EQP5)
Organism: Rattus norvegicus (Rat)
Function: May anchor basement membranes to the underlying connective tissue.
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- Dermatopontin
- Lumican
- Fibromodulin
- Aggrecan core protein
- Mimecan
- Osteomodulin
- Adhesion G protein-coupled receptor L2
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L1
Sequence:
MRASFFWFLPLLLILASVAQGQPRPKPGIRRKPKPRPTPSFPQPHEPAEPTDLPPPLPPGPPSVFPDCPRECYCPPDFPSALYCDSRNLRKVPIIPPRIHYLYLQNNFITELPVESFKNATGLRWINLDNNRIRKVDQRVLEKLPGLAFLYMDKNQLEEVPSALPRNLEQLRLSQNLISRIPPGVFSKLENLLLLDLQHNRLSDGVFKADTFQGLKNLMQLNLAHNILRRMPPKVPPAIHQLYLDSNKIETIPSGYFKDFPNLAFIRMNYNKLSDRGLPKNSFNISNLLVLHLSHNKISNVPAISNKLEHLYLNNNSIEKINGTQICPSNLVAFHDFSSDLENVPHLRYLRLDGNFLKPPIPLDLMMCFRLLQSVVI