wanglab/gogpt-training-data huggingface dataset:
Protein: Orexigenic neuropeptide QRFP (P518) [Cleaved into: QRF-amide (Neuropeptide RF-amide) (Pyroglutamylated arginine-phenylalanine-amide peptide)] (P83860)
Organism: Rattus norvegicus (Rat)
Function: Stimulates feeding and grooming behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland.
Subcellular location: Secreted.
Interaction partners:
- Pyroglutamylated RF-amide peptide receptor
- Neuropeptide FF receptor 2
- Pro-FMRFamide-related neuropeptide FF
- Neuropeptide FF receptor 1
- Pro-FMRFamide-related neuropeptide VF
- Prolactin-releasing peptide
- Prolactin-releasing peptide receptor
- Galanin peptides
Sequence:
MRCLCSWLCLLLPLSACFPLLDRRGPTDIGDIGARMSWVQLTEGHTPRSVQSPRPQALLVVAKEQQASRREHTGFRLGRQDSGSEATGFLPTDSEKASGPLGTLAEELSSYSRRKGGFSFRFGR
Protein: ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3) (Q2HXL6)
Organism: Mus musculus (Mouse)
Function: Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. May also participate in mannose trimming from all glycoproteins and not just misfolded ones targeted to ERAD. May have alpha 1,2-mannosidase activity.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:16431915}.
Interaction partners:
- ER degradation-enhancing alpha-mannosidase-like protein 1
- ER degradation-enhancing alpha-mannosidase-like protein 2
- Protein OS-9
- Protein sel-1 homolog 1
- UDP-glucose:glycoprotein glucosyltransferase 1
Sequence:
MSKAGGCRGCGCRVPQRASWSLVAATAALCLVLATSVCTAGAAPMSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEHMQWYNDELLHMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDSYYEYLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTWMDALLAFFPGLQVLKGDIRPAIETHEMLYQVIKKHNFLPEAFTTDFRVHWAQHPLRPEFAESTYFLYKATGDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLYLLFADKEDIIFDIEDYIFTTEAHLLPLWLSTTNRSISKKNTTSEYTELDDSNFDWTCPNTQILFPNDPLYAQSIREPLKNVVDKSCPRGIIRVEESFRSGAKPPLRARDFMATNPEHLEILKKMGVSLIHLKDGRVQLVQHAIQAASSIDAEDGLRFMQEMIELSSQQQKEQQLPPRAVQIISHPFFGRVVLTAGPAQFGLDLSKHKETRGFVASSKPYNGCSELTNPEAVMGKIALIQRGQCMFAEKARNIQNAGAIGGIVIDDNEGSSSDTAPLFQMAGDGKDTDDIKIPMLFLFSKEGSIILDAIREHEQVEVLLSDKARDRDPEMENEDQPSSENDSQNQSAEQMLSLSQTVDLADKESPEHPADSHSEASPSDSEEAAGFAPSEQISGSTENHETTSLDGECTDLDNQVQEQSETEEDSSPNVSWGTKAQPIDSILADWNEDIEAFEMMEKDEL
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Complex I-B22) (NADH-ubiquinone oxidoreductase B22 subunit) (E9PH64)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004443}; Matrix side {ECO:0000256|ARBA:ARBA00004443}.
Interaction partners:
Sequence:
MAFLASGPYLTHQQKVLRLYKRALRHLESWCVQRARFEEHKNEKDMAKATQLLKEAEEEFWYRQHPQPYIFPDSPGGTSYERYDCYKVPEWCLDDWHPSEKAMYPDYFAKREQWKKLRRESWEREVKQLQEETPPGGPLTEALPPARKEGDLPPLWWYIVTRPRERPM
Protein: Calbindin 2 (A6NER6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKMKEFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRIEAATLTSMSWMPF
Protein: histidine kinase (EC 2.7.13.3) (G3XD98)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004429}.
Interaction partners:
- histidine kinase
- Response regulator GacA
- histidine kinase
- Probable two-component response regulator
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- Sensory/regulatory protein RpfC
- histidine kinase
Sequence:
MFKDLGIKGRVLLLTLLPTSLLAMVLGGYFTWVQLSDMRAQLIERGQLIAEQLAPLAATALARKDTAVLNRIANEALDQPDVRAVTFLDARQERLAHAGPSMLTVAPAGDASHLSMSTELDTTHFLLPVLGRHHSLSGATEPDDERVLGWVELELSHHGTLLRGYRSLFTSLLLIAAGLGVTALLALRMSRAINAPLELISQGVAQLKEGRMETRLPPMGSNELDELASGINRMAETLQSAQEEMQHNIDQATEDVRQNLETIEIQNIELDLARKEALEASRIKSEFLANMSHEIRTPLNGILGFTNLLQKSELSPRQQDYLTTIQKSAESLLGIINEILDFSKIEAGKLVLENLPFNLRDLIQDALTMLAPAAHEKQLELVSLVYRDTPIQLQGDPQRLKQILTNLVGNAIKFTQGGTVAVRAMLEDESDDRAQLRISVQDTGIGLSEEDQQALFKAFSQADNSLSRQAGGTGLGLVISKRLIEQMGGEIGVDSTPGEGAEFWISLSLPKSRDDNEEPGASWAAGQRVALLEPQELTRRSLHHQLTDFGLEVSEFADLDSLQESLRNPPPGQLPISLAVLGVSAAIHPPEELSQSFWEFERLGCKTLVLCPTTEQAQYHATLPDEQVEAKPACTRKLQRKLQELLQVRPTRSDKPHAMVSGRPPRLLCVDDNPANLLLVQTLLSDLGAQVTAVDSGYAALEVVQRERFDLVFMDVQMPGMDGRQATEAIRRWEAEREVSPVPVIALTAHALSNEKRALLQAGMDDYLTKPIDEQQLAQVVLKWTGLSLGQSLASMSRAPQLGQLSVLDPEEGLRLAAGKADLAADMLAMLLASLAADRQAIRQARDNDDRTALLERVHRLHGATRYCGVPQLRAACQTSETLLKQNDPAAAAALDELDKAIEALADTASATTHLSSTSLDSSEL
Protein: Plasma membrane fusion protein (Q8H0U2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transmembrane protein
- Large ribosomal subunit protein P2z
- 28 kDa heat/acid-stable phosphoprotein-like protein
- Ureide permease 5
- Probable serine/threonine-protein kinase PIX13
- Defensin-like protein 206
- Myosin-1
- Branched-chain-amino-acid aminotransferase 5, chloroplastic
- Glutathione reductase, cytosolic
Sequence:
MLCFRSQRVFILVSLCLLSSFLVVVTGTTSITGVGNEEERGVEEEWRTSVIERVIAEESGENSSLILAAKRTRRKDPADNFKLYTGGWNISNSHYLTSVGYTAAPFIIIALVWFVFFGLSLSLICLCYCCCARQSYGYSRVAYALSLILLISFTIAAIIGCVFLYTGQGKFHASTTDTLDYVVSQANLTSENLRNVSDYLNAAKKVDVQSSILPQDVLSSIDNIQGKINSSATTLSVKTMENQDKIQNVLDIMRLALVIIAAVMLFLAFIGFLLSIFGLQCLVYTLVILGWILVTVTFVLCGGFLLLHNVVGDTCVAMDQWVQNPTAHTALDDILPCVDNATARETLTRTKLVTYQLVNLLDNAISNMTNRNFPPQFRPLYYNQSGPLMPLLCNPFNADLSDRQCQPGQVHLNNATEVWKNFTCQIVTPGTCSTPGRLTPKLYSQMAAAVNVSYGLYKYGPFLADLQGCDFVRSTFTDIERDHCPGLKRYTQWIYVGLVVVSASVMSSLVFWVIYARERRHRVYTKDYNAMHSEDPRSKGH
Protein: Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (MPTP-PEST) (Protein-tyrosine phosphatase P19) (P19-PTP) (P35831)
Organism: Mus musculus (Mouse)
Function: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2. Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248' (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12674328, ECO:0000269|PubMed:7772023}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q05209}. Cell projection, podosome {ECO:0000269|PubMed:12674328}. Note=Partial translocation to focal adhesion sites might be mediated by interaction with SORBS2. {ECO:0000250|UniProtKB:Q05209}.
Interaction partners:
- SHC-transforming protein 1
- Proline-serine-threonine phosphatase-interacting protein 1
- Leupaxin
- Focal adhesion kinase 1
- Epidermal growth factor receptor
- Protein-tyrosine kinase 2-beta
- Breast cancer anti-estrogen resistance protein 1
- Growth factor receptor-bound protein 2
- Pro-epidermal growth factor
- Paxillin
Sequence:
MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCENEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGNEITTGTMVSSIDSEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDSDRYHPKPVLHMASPEQHPADLNRSYDKSADPMGKSESAIEHIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASSSVVDRTSKPQELSAGALKVDDVSQNSCADCSAAHSHRAAESSEESQSNSHTPPRPDCLPLDKKGHVTWSLHGPENATPVPDSPDGKSPDNHSQTLKTVSSTPNSTAEEEAHDLTEHHNSSPLLKAPLSFTNPLHSDDSDSDGGSSDGAVTRNKTSISTASATVSPASSAESACTRRVLPMSIARQEVAGTPHSGAEKDADVSEESPPPLPERTPESFVLADMPVRPEWHELPNQEWSEQRESEGLTTSGNEKHDAGGIHTEASADSPPAFSDKKDQITKSPAEVTDIGFGNRCGKPKGPREPPSEWT
Protein: Developmental pluripotency-associated protein 5A (mDppa5) (ES cell-associated transcript 2 protein) (Embryonal stem cell-specific gene 1 protein) (ESG-1) (Protein pH 34) (Q9CQS7)
Organism: Mus musculus (Mouse)
Function: Involved in the maintenance of embryonic stem (ES) cell pluripotency. Dispensable for self-renewal of pluripotent ES cells and establishment of germ cells. Associates with specific target mRNAs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16166252, ECO:0000269|PubMed:16872451}.
Interaction partners:
- Developmental pluripotency-associated protein 3
- Homeobox protein NANOG
- Developmental pluripotency-associated protein 4
- Zinc finger protein 42
- POU domain, class 5, transcription factor 1
- Developmental pluripotency-associated protein 2
- Undifferentiated embryonic cell transcription factor 1
Sequence:
MMVTLVTRKDIPPWVKVPEDLKDPEVFQVQSLVLKYLFGPQGSRMSHIEQVSQAMFELKNLESPEELIEVFIYGSQNNKIRAKWMLQSMAERYHLRQQKGVLKLEESMKTLELGQCIE
Protein: Melanopsin opn4x1 (Opsin 4xa) (Xenopus-like melanopsin-1) (F1QZ18)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}.
Interaction partners:
Sequence:
MEESKDMDRGFFRKVDVPDHAHYIVAFFVAVIGALGVIGNLLVMYAFFSNKKLRTPPNYFIMNLAVSDFLMAITQSPIFFINCMYKEWVFGEMGCKMYAFCGALFGITSMINLLAISIDRYIVITKPLQAIRWTSGRRTLIIILVVWIYSLAWSLAPLIGWSSYIPEGLMTSCTWDYVTSTPANKSYTLMLCCFVFFIPLGIISYCYFFMFLAIRSASRDVEKLGSHVRKTTLIQQQSIKTEWKLAKIAFVVIIVFVLSWSPYACVTLIAWAGYSHVLSPYSKAVPAVIAKASAIYNPFIYAIIRSKYRDTLAEKVPCLHFLAQSSRKDVSVSNSESSFREHMLSRQSSGSKAKFQRISSMSTADTVWSDVEIDPVDQKSQTIRNSQSASLLRDDKWKAQTKQDYQNDRESSEEKSAITDSGGSLSGGGLDLVSESINMATVPLLMAKNTGEEDQEEEEDETLTGQQDSRSLSPISNDLPFYQDTEEPHITLSPTSAEQQSTETRENNLILELKSLNCSSELLESVEKFLS
Protein: Glucan endo-1,3-beta-glucosidase (EC 3.2.1.39) (Beta-1,3-glucanase) (allergen Mus a 5) (O22317)
Organism: Musa acuminata (Banana) (Musa cavendishii)
Function: Possesses beta-1,3-endoglucanase activity in vitro. May play a role in fruit pulp softening process (Probable). Can cleave beta-1,6-branched glucans in vitro.
Interaction partners:
Sequence:
MATKASLSIKGFALLVSVLVAVPTRVQSIGVCYGMLGNNLPPPSEVVSLYKSNNIARMRLYDPNQAALQALRNSNIQVLLDVPRSDVQSLASNPSAAGDWIRRNVVAYWPSVSFRYIAVGNELIPGSDLAQYILPAMRNIYNALSSAGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQAYLSPIVQFLASNGAPLLVNVYPYFSYTGNPGQISLPYALFTASGVVVQDGRFSYQNLFDAIVDAVFAALERVGGANVAVVVSESGWPSAGGGAEASTSNARTYNQNLIRHVGGGTPRRPGKEIEAYIFEMFNENQKAGGIEQNFGLFYPNKQPVYQISF
Protein: NAD(P)H-quinone oxidoreductase subunit U, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit U) (NDH subunit U) (NADH-plastoquinone oxidoreductase subunit U) (Protein CHLORORESPIRATORY REDUCTION L) (Q84VQ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:21505067}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- NAD
- Photosynthetic NDH subunit of subcomplex B 1, chloroplastic
- NAD
- Photosynthetic NDH subunit of subcomplex B 2, chloroplastic
- NAD
- NAD
- Photosynthetic NDH subunit of subcomplex B 5, chloroplastic
- Photosynthetic NDH subunit of subcomplex B 4, chloroplastic
- NAD
- Photosystem I chlorophyll a/b-binding protein 6, chloroplastic
Sequence:
MASLSTITQPSLVHIPGESVLHHVPSTCSFPWKPTINTKRIICSPARNSSEVSAEAETEGGSSTAVDEAPKESPSLISALNVERALRGLPITDVDHYGRLGIFRNCSYDQVTIGYKERVKELKEQGLDEEQLKTKMDLIKESYTILSTVEERRMYDWSLARSEKAERYVWPFEVDIMEPSREEPPPQEPEDVGPTRILGYFIGAWLVLGVALSVAFNR
Protein: N-terminal EF-hand calcium-binding protein 2 (EF-hand calcium-binding protein 2) (Neuronal calcium-binding protein 2) (F1LQY6)
Organism: Rattus norvegicus (Rat)
Function: May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17689978}. Cell projection, dendrite {ECO:0000269|PubMed:17689978}. Cell projection, axon {ECO:0000269|PubMed:17689978}. Cell membrane {ECO:0000250|UniProtKB:Q7Z6G3}. Note=Colocalizes with ADORA2A and/or mGluR5/GRM5 at the plasma membrane (By similarity). Found in neuronal somata (PubMed:26843217). Detected in the cytoplasm of striatal neurons, at postsynaptic sites, filling dendritic shafts and spines, and at presynaptic sites, filling axon terminals (PubMed:17689978). {ECO:0000250|UniProtKB:Q7Z6G3, ECO:0000269|PubMed:17689978, ECO:0000269|PubMed:26843217}.
Interaction partners:
- Adenosine receptor A2a
Sequence:
MCERAARLCRAGAHRLLREPPPQGRALGGLLRWVGARMGEPRAPLVPDIPAADPDPGPAAPRGGTAVILDIFRRADKNDDGKLSLEEFQLFFADGVLNEKELEGLFHTIDSDNTNHVDTKELCDYFVEHMGDYEDVLASLETLNHSVLKAMGYTKKVYEGGNNVDQFVTRFLLKETANQIQSLLSSVESAVEAIEEQTSQIRQDHCKPSPGVNESRYGGPTPPYIPNHKLVVPEPVKSLPVAIGEPKEEGLEVQISRLAELIGRLESKTLSFDLQQRLSDEEGTNMYLQLVRQEMAVCPEQLGEFLDSLRQYLRSTAEERNCFHVAAVRMADGLTFVIYEFWETEEEWKRHLQSPVCKAFRHVKVDTLSQPEALSQISVPAAWCTSGRD
Protein: Vasodilator-stimulated phosphoprotein isoform 1 (A0A024R0V4)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, lamellipodium {ECO:0000256|ARBA:ARBA00004510}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPPPPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVPAQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQKVKEEIIEAFVQELRKRGSP
Protein: Max-like protein X (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4) (O08609)
Organism: Mus musculus (Mouse)
Function: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Subcellular location: [Isoform Alpha]: Cytoplasm {ECO:0000250|UniProtKB:Q9UH92}. Note=Found predominantly in the cytoplasm. {ECO:0000250|UniProtKB:Q9UH92}.; SUBCELLULAR LOCATION: [Isoform Beta]: Cytoplasm {ECO:0000250|UniProtKB:Q9UH92}. Note=Found predominantly in the cytoplasm. {ECO:0000250|UniProtKB:Q9UH92}.; SUBCELLULAR LOCATION: [Isoform Gamma]: Nucleus {ECO:0000250|UniProtKB:Q9UH92}. Note=Found predominantly in the nucleus. {ECO:0000250|UniProtKB:Q9UH92}.
Interaction partners:
- MLX-interacting protein
- Carbohydrate-responsive element-binding protein
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- Peroxisome proliferator-activated receptor gamma coactivator 1-beta
- Serine/threonine-protein phosphatase 2A activator
- Max-binding protein MNT
Sequence:
MTEPGASPEDPWVKASFADAHAGEGRAGRARARRGSGRRGAPQLSPESPLLSGARGCREDSSHPACAKVEYAYSDNSLDPGLFVESTHKGSVVSRANSIGSTSASSVPNTDDEDSDYQQEAYKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCEPQTLREIVIGVLHQLKNQLY
Protein: Eukaryotic translation initiation factor 4G1, isoform B (A8DZ29)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Eukaryotic translation initiation factor 4E1
- Polyadenylate-binding protein
- Eukaryotic initiation factor 4A
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- Eukaryotic initiation factor 4B
- Eukaryotic translation initiation factor 5
Sequence:
MQQAIPTLPTQSDIDKAMQPHSAQNMILPANKKTKKYDQQVPTSKPQSLHQPLQPQHSHPTAQPQFQINKAYNVVSILKASAQIAQQSPHLTNQQHPPIHHPQQTQQHQQSYTNVVNRSLSASEPVRAQSSVICNGSSILTVNSRQLNSGDMNSTAIYNISSYRKLTGSLDGNVCFLNVQDIKQNGNISGSVVSNKSIVGVGSEKSSCTGVSINNQIVLPNAQIGTSMGIAGTTTAGTSYMHEKNIVGVSVNCVNTSKKYDFNNSSLLSNNSYPASTAEYVSTGNNNSGNTRSNPQSGGIFRGPPSTPNAPRGASGGATRHVHVQPMYSQPLHQNMVLQQYTQYNPRQQTFPASHLQYAPAPMPYYQYQYVPTLQQQPPHTRSAVTVNTNVNVGNNLQPVQSGPNGPLPVPGASSSQIQLLTSTVQPGASTVMGVGGPGSTMGQVGVPPMVGVGVMTTSVQPQPVQVQPASRRRHQHRLQIIDPTTKKNILDDFDKTKSNTDNEFSDQVTSTNTPATVLSEGPIRIPQQESVGLNNLTSTSSQGSESRTNAPYIPIETTPISRTDVGPTPIVSAMTDAPSVEILPTPQRGRSKKIPIVSPKNVSESIVAPITDETDDAGSTPISRATEESMPPNQTHPNLLISDSSKHKQAVSNSEISKDAPTGLKEMHVAELESSVASENHPAGILDVNVNKSSQSLDFSADPEIDSIGAISPTSPNAVSPILHEVLDNTELSKKLENSTTERFKDSQSVEKPTHQELSLRNATDETEISAMALQDVNSLDNNQIEKTYPSKPKLNVDVSEDISSRESAIKSTSTKNTGVDVGLQSDSKPETTLNDKQDSTDLKVKVSAKISSIINYNEGQWSPNNPSGKKQYDREQLLQLREVKASRIQPEVKNVSILPQPNLMPSFIRNNNNNKRVQSMVGIIGNRSNESAGNYIGKQMSMSGVQSGGGRSSMKGMIHVNLSLNQDVKLSENENAWRPRVLNKSDGDSDAKSALEKDELVRRVRGILNKLTPERFDTLVEEIIKLKIDTPDKVDEVIVLVFEKAIDEPNFSVSYARLCQRLAAEVKVIDERMESETKSNSAHFRNALLDKTEQEFTQNVSQSTAKEKKLQPIVDKIKKCTDANEKAELEAFLEEEERKIRRRSGGTVRFIGELFKISMLTGKIIYSCIDTLLNPHSEDMLECLCKLLTTVGAKFEKTPVNSKDPSRCYSLEKSITRMQAIASKTDKDGARVSSRVRFMLQDVIDLRKNKWQTSRNEAPKTMGQIEKEAKNEQLSAQYFGTLSSTTPGGSQGGSGKRDDRGNSRYGESRSSSAYGGSHSQRGDNGNLRHQQQNNVGGNVSGGAGHSNGNNDENTWHVQTSKGSRSLAVDSNKLEGLSKLSDQNLETKKMGGLTQFIWISSDTTRLSSAPTPTPSNPFAVLSSLIDKNSNERDRDRSGPRNKGSYNKGSMERDRYDRGMHSRTGSSQGSRENSSSRGGQQGRTLLSSSVQKSTSHSKYTQQAPPTRHTVKAQSSVGSSNVNTGPLYRGSEQQTSATFSQTTRSVAPVAVFIEASETDLKLIKSVVSEIVDLSAASKEVTPGAVSCIKRVPEKLRCSFIYYILTDYLHLANVGKQYRRYLSIAVSQLIQQNYISADHLRLAYNEFTVYANDLIVDIPELWLYILQFAGPLIVKKILTISDLWNNNLKENSPSNVAKKFLKTYLIYCTQEVGPNFARNMWIKFNLKWSDFMPESEVADFIKFNRLEYVENESKSPVIDHRETPEKHVKNVIDHIEHLLKEGTTADCIIDYSNGNIMVVDKLFIRGLTETLSNFSIHYKDNSYKLESETFQKFCIPVLQRYIDSNEDHQLECLYTLQLLVHGLEHPRGLLSELIGELYDAFVIQKESLCKWRDSKDQSAGKGVAVKSLNPFFNSLLNDDAN
Protein: Tetraspanin (Q9NB16)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
Interaction partners:
Sequence:
MHPHHFTYVSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFYDVFLNISLVMILAGTDIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATDISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLAKTLEGQIELQKSRWLA
Protein: Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic (RA) (RuBisCO activase) (Q9AXG1)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Plastid, chloroplast stroma {ECO:0000256|ARBA:ARBA00004470, ECO:0000256|RuleBase:RU369045}.
Interaction partners:
Sequence:
MAAAVSTIGAVNRAPLSLNGSGAGASAPSSAFMGNSLKKVSARFNNNGKAPVGSFKIVAAKEIDEDTQTDQDRWKGLAYDISDDQQDITRGKGMVDSLFQAPMNDGTHYAVMSSYEYISQGLRTYDLDNNMDGFYIAPAFMDKLVVHITKNYMTLPNIKVPLILGIWGGKGQGKSFQCELVFAKMGINPIMMSAGELESGNAGEPAKLIRQRYREAADIIKKGKMCCLFINDLDAGAGRMGGTTQYTVNNQMVNATLMNIADNPTNVQLPGMYNKEENPRVPIIVTGNDFSTLYAPLIRDGRMEKFYWAPTREDRIGVCTGIFRTDNVPVDDIVKLVDTFPGQSIDFFGALRARVYDDEVRKWIGEVGVNSVGKKLVNSREGPPSFEQPTMTIEKLLEYGNMLVAEQENVKRVQLADKYLSEAALGNANDDAIKRGAF
Protein: Oligo-1,6-glucosidase IMA2 (EC 3.2.1.10) (Alpha-glucosidase) (Isomaltase 2) (Q08295)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose.
Interaction partners:
- Invertase 2
- Glucoamylase, intracellular sporulation-specific
- General alpha-glucoside permease
- Low-affinity methionine permease
- High-affinity methionine permease
- Mannosyl-oligosaccharide glucosidase
- Hexose transporter HXT11
- Maltose fermentation regulatory protein MAL13
- Hexose transporter HXT9
Sequence:
MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQPSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMQHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE
Protein: Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (O88582)
Organism: Rattus norvegicus (Rat)
Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O14508}.
Interaction partners:
- Cullin-5
- Tyrosine-protein kinase JAK2
- Suppressor of cytokine signaling 3
- Suppressor of cytokine signaling 1
- Insulin receptor substrate 1
- Elongin-C
- Insulin receptor substrate 2
- Insulin receptor
- Elongin-B
- Insulin receptor substrate 3
Sequence:
MTLRCLEPSGNGADRTRSQWGTAGSPEDQSPEAARLAKALRELSQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPTLQHFCRLSINKCTGTIRGLPLPTRLKDYLEEYKFQV
Protein: Cut9-interacting protein scn1 (P41890)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Interacts with cut9.
Interaction partners:
Sequence:
MESIIDAHCHPTDAPQELHLVANLSVGKLIVMGTRPTDQKYVEQLAKEYPGKVIPSFGIHPWFSYYLYDDLDKDLQSSETRKKKHYEKILTPIPDEDFINALPNPVPISEFLEDARRHLKQYPNALIGEIGLDKPFRLPVGPYDARSSLPQGPLSPFYVKMEHQCKVFEAQVRLAAEFQRAVSVHCVQTYALLYSSLAKFWDGRWIPSKTKIRKMKKEEYENSLAEERKHYPPKICLHSYSGSIEQISQFSAHKVPTEFYYSFSIGINSRYKNFIQTLKGVPDDKLLAESDHHSASQIDELVRQSLNVMSEAKSWTFEDTITKISSNSKAFLKVT
Protein: aspartyl aminopeptidase (EC 3.4.11.21) (Q57V45)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cyclosome subunit 1, putative
- Uncharacterized protein
Sequence:
MLPLDSPPVTQLAKEFVNFINEACTPFHAVEVLSSWLSNAGYQRLKEGETWPKLTNGYRYFITRNDSSLVAFSVGGRFVAENGLKIVGAHTDSPNLALKPRTLAGRSDYQGVAVQCYGGGLWHTWFDRDLTVAGRVIISSSKLVKRLVKVNKPIMRIPTLAIHLQSVEERNAFGPNKEKHLVPVIATTLSHTPNGDVSEHHNSQLLILLAESLGCRPSEIVDYDLSVVDTQDAVVGGANDEFIYAPRLDNLISCFCGVKALLESDKTLEEENMIRMVCLFDNEEVGSSTSQGAGGSLVPDVIEYISASGGLRAQLVANSFLMSVDGAHAVHPNYQDKHEEKHRPLIHRGPVIKYNANMRYATNGVTAAIVKAIAKRASVPIQEFCVKNDSPCGSTIGPILSSLSGIQTVDLGNPMLSMHSIREMCGTADLLHLKNLLEAFFNHYTRDMVTS
Protein: Alpha/beta-Hydrolases superfamily protein (Q8VZ57)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Serine carboxypeptidase-like 26
- Serine carboxypeptidase-like 42
- Serine carboxypeptidase-like 34
- Prolyl carboxypeptidase like protein
- Proteasome subunit alpha type-5-B
- Aminopeptidase P2
- Subtilisin-like protease SBT4.1
- Stromal processing peptidase, chloroplastic
- Probable envelope ADP,ATP carrier protein, chloroplastic
- Serine carboxypeptidase-like 46
Sequence:
MSLLSPLPLLHSFSSTVATKSTASRITATPSKIRFSVINATSENGNSGGSKNDRDEDPSFNPFGFVTDNPSSRSAIQLPESPAEDGNVGQMLYRTEDKGKEYGSTIKSGKLRWFVRETGSKESRRGTIVFVHGAPTQSFSYRTVMSELSDAGFHCFAPDWIGFGFSDKPQPGYGFNYTEKEYHEAFDKLLEVLEVKSPFFLVVQGFLVGSYGLTWALKNPSKVEKLAILNSPLTVSSPVPGLFKQLRIPLFGEFTCQNAILAERFIEGGSPYVLKNEKADVYRLPYLSSGGPGFALLETAKKINFGDTLSQIANGFSSGSWDKPTLLAWGIADKYLPQSIAEEFEKQNPQNVKLRLIEGAGHLPQEDWPEKVVAALRAFF