wanglab/gogpt-training-data huggingface dataset:
Protein: Lon protease (EC 3.4.21.53) (ATP-dependent protease La) (Q9I5F9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_01973, ECO:0000256|PIRNR:PIRNR001174}.
Interaction partners:
- ATP-dependent protease ATPase subunit HslU
- Chaperone protein DnaK
- ATP-dependent protease subunit HslV
- Chaperone protein HtpG
- Protein GrpE
- Chaperone protein DnaJ
- Chaperonin GroEL
- ATP-dependent Clp protease proteolytic subunit 1
- Chaperone protein ClpB
- ATP-dependent Clp protease ATP-binding subunit ClpX
Sequence:
MSDQDVNPEHISDAQPAGTGLVLPGQTLPTTLYVIPIHNRPFFPAQVLPVIVNEEPWAETLELVAKTDHHSLALFFMDNPPEDPRHFDVNSLPEHGTLVRVHHASREGGKLQFVAQGLSRVRIRGWIKRHRPPFMVEVDYPKTPIDPSDEVKAYGMALINAIKELLPLNPLYSEELKNYLNRFSPNDPSPLTDFAAALTTAPGGELQEVLDTVPILKRMEKVLPLLRKEVEVARLQKELSAEVNRKIGEHQREFFLKEQLKIIQQELGITKDDKSADADEFRARLEGKVLPEQARKRIDEELNKLSILESGSPEYAVTRNYLDWATALPWGVYGKDKLDLKHARKVLDKHHAGLDDIKDRILEFLAVGSFKGEIAGSIVLLVGPPGVGKTSIGKSIAESLGRPFYRFSVGGMRDEAEIKGHRRTYIGALPGKLVQALKEVEVMNPVIMLDEIDKLGASYQGDPASALLETLDPEQNVEFLDHYLDLRLDLSKVLFVCTANTLDSIPGPLLDRMEVIRLSGYISEEKLAIAKRHLWPKQLEKAGVPKGRLSISDAALRAVIEGYAREAGVRQLEKQLGKLVRKSVVKLLEDPESKVKIGPRDLEDYLGMPVFRSEQVLSGIGVITGLAWTSMGGATLPIEATRIHTLNRGFKLTGQLGDVMKESAEIAYSYIGSHLKKYGGDPTFFDQAFVHLHVPEGATPKDGPSAGVTMASALLSLARNQVPKKGVAMTGELTLTGQVLPIGGVREKVIAARRQKIFELILPEANRGHFEELPDYLREGLTVHFAKRYGDVAKVLFPA
Protein: Semaphorin-3C (Semaphorin-E) (Sema E) (Q62181)
Organism: Mus musculus (Mouse)
Function: Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Neuropilin-1
- Neuropilin-2
- Plexin-D1
- Plexin-A2
- Plexin-A1
- Plexin-A3
- Plexin-A4
Sequence:
MAFRAICVLVGVFICSICVRGSSQPQARVYLTFDELRETKTSEYFSLSHQQLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKERLTDNNRSTKQIHSMIARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSASGELILEELEVFKNHVPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVRNNSTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQDSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWAGSVRALPFHPKDILGAFSHSEMQLINQYCKDTRQQQQLGEEPQKMRGDYGKLKALINSRKSRNRRNQLPES
Protein: Multiple organellar RNA editing factor 6, mitochondrial (RNA editing-interacting protein 6) (O82169)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in organellar RNA editing. Required for the processing of few RNA editing sites in mitochondria.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25583991}.
Interaction partners:
Sequence:
MAKTLSRSTASCVAKRFFSTSNAVASPSPLPSHLISRRFSPTIFHAVGYIPALTRFTTIRTRMDRSGGSYSPLKSGSNFSDRPPTEMAPLFPGCDYEHWLIVMEKPGGENAQKQQMIDCYVQTLAKIVGSEEEARKKIYNVSCERYFGFGCEIDEETSNKLEGLPGVLFVLPDSYVDPEFKDYGAELFVNGEVVPRPPERQRRMVELTNQRGSDKPKYHDRIRNVRRRENMR
Protein: SH2/SH3 adapter protein dreadlocks (Q8IPW2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Perikaryon {ECO:0000269|PubMed:10068645}. Cell projection, axon {ECO:0000269|PubMed:10068645, ECO:0000269|PubMed:10399914, ECO:0000269|PubMed:8646773}. Cell projection, growth cone {ECO:0000269|PubMed:10068645, ECO:0000269|PubMed:10399914, ECO:0000269|PubMed:8646773}. Note=Highest concentration localized to the growth cones of neuronal cells. {ECO:0000269|PubMed:10068645}.
Interaction partners:
Sequence:
MLEHPQRFVRNIPDSSASSQQYPQQQQHPPQLPQHQNLNLNQNQNLNQNQIYQYRPQVPVPVPGSPAHHQRHSSLSQQQQLHHHRTLSTASSCSAQHKSVTFGQPALDCGGNGSGSANGSGSGNSSSGSAAGNAGTQSMAGNMKHGKSQDDVCYVVAKYDYAAQGAQELDLRKNERYLLLDDSKHWWRVQNSRNQSGYVPSNYVKKEKPSLFDSIKKKVKKGSGSKTLPNCSPSRQVESPTMSRRLPPDPAEAIGTAVVKYNYQAQQPDELSLTKGTRILILEKSNDGWWRGQSGNSVGWFPSNYTTEDCDNDGEIHTYAMAENVLDIVVALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRNASASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCIGQRKFHSLDQLVDHYQRAPIYTNKQGEKLYLVRSLPKANGT
Protein: Unconventional myosin-XIX (Myosin head domain-containing protein 1) (Q96H55)
Organism: Homo sapiens (Human)
Function: Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis. May be involved in mitochondrial transport or positioning.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:19932026, ECO:0000269|PubMed:23568824, ECO:0000269|PubMed:25447992, ECO:0000269|PubMed:26659663, ECO:0000269|PubMed:27126804}; Peripheral membrane protein {ECO:0000269|PubMed:27126804}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19932026}.
Interaction partners:
- Mitochondrial Rho GTPase 2
- Mitochondrial Rho GTPase 1
- Trafficking kinesin-binding protein 2
- Trafficking kinesin-binding protein 1
Sequence:
MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAVEGLEWSFINYQDNQPCLDLIEGSPISICSLINEECRLNRPSSAAQLQTRIETALAGSPCLGHNKLSREPSFIVVHYAGPVRYHTAGLVEKNKDPIPPELTRLLQQSQDPLLMGLFPTNPKEKTQEEPPGQSRAPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQTFLQEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAIIRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQGSIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG
Protein: 60S acidic ribosomal protein family (60s acidic ribosomal protein P1) (Q9FLV1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL29z
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein uL10y
- Large ribosomal subunit protein eL38z/eL38y
- Small ribosomal subunit protein uS2z
- Large ribosomal subunit protein eL42z/eL42y
- Small ribosomal subunit protein eS6y
- Large ribosomal subunit protein eL22z
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
Sequence:
MSTSELACTYAALILHDDGIEITAENISKLVKTANVNVESYWPSLFAKLCEKKNIDDLIMNVGAGGCGVARPVTTAAPTASQSVSIPEEKKNEMEVIKEESEDDMIIGLFD
Protein: Phosphoinositide phospholipase C (EC 3.1.4.11) (C5H807)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MRLHVERQAHIGIKSSMASNRASPVLGVKSLGKETSSNGDARLLMNYSLPGGTPPQTPVHLEGDSVGTVCRIWKSLDIRSKSLDCLDETFRSKNCSCEAIRHREEGSYNFHMCGFCDSVENAEGCPKNTFSPRSWGTVPQKRKAEAFSSGITSLDEPRPTLSGSDGELCPKELVISQNMENLPFCGLDLRRSSVPVSTPQGPQCANGCGTAENNKMRNRLDFVCAICHKNGFSSLERLNRNTKPMCSKGKPLKRSKPFRFSVPDSSDGEGTVSDSEFVRNRKDRSTVLVRRYLKNNQKFKKTVCTGTKAIVKTLPTGCISDRIWESVCNERSRHEASGHSKALQAIQLQVSRALLAYPGARLAEIDHAAPTLSPEVSLLHRSRKLLAQAVSWPPVSPSQIRFRACHRRISIAAHLSGALLVATAALGARTSLPSFTVGSTGRAMLKERQLCSSMANSSILPSAVTGISKELADLRHLIQFPEEIATILTEQEQQLYRRVFPLDYLSFLTRDLGSPECHKRHPHLKASLSAPIMPTQNDNHNTVEDLVTRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCSWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQADIETMRGLKDAMAQHESSSEYKKVVSRALNIPGCKVVPFCGVFLKELSEALDGAASIIGLRPSFDSQEDPVEFVTDYNGQQHFLQRLGSDGLHSSDKEATVSNILQTIRSCNRSLEAEEPEERAREITVCPKNSFKDKSRNQKGPGTERVLFSIGDLSDSEGDPLETVKDVVDLQTTEDVRGPFSHGTELIPWYVLSLQPDIHQFLLQGATVIHYDPESHLTARCLLRLQPDNCFLTWCKPHSSCSLYGRARTFMGHPASPDHLHIGQPVHCGLSDGLLDLNVVKAVFMGHPGVDVNYVCLQHKLCNMNPGGNGATLLYGLHTTDNRLLHFVAPKHTARMLHEGLQELLNSIRKIRKFPDQRLQWLRKQYVSLYQEDGRFEGPTLAHAIELFGGRRWNMGTSGPGSASRSAEKNSAQKNSPLGINSNVKKKKKALVRGDSGDGTDDEMTARKTRGCKETLGRRESDPLENVEQGEAEDCSTFSQPGPSSLSNNKGQSPGSSSSSSTSSSVASFCTNSSTPTRPHSSPILPTNLKSQPGAWSSRSWHGRGKGCFRGFQDLMISDSIMSFVEFVELFKSFSIRSRKDLKELFDTYAVPCSRSGPESVPLYTTLRIDDKLTGLQPDLDLLTRNGSDLGLFIRTRQQMSENQKQISDAIAAASIVTNGTGVENSSLGVLGLAISQLNDFLVNCQREHLSYDEILSIIQKFEPSSNMRQMGWMSFEGFARFLMDKDNFASKNEESQVNLDELQHPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPVIYHGHTLTTKIPFKDVVEAINRAAFVNSEMPVILSIENHCSLPQQRKMAEIFKMVFGEKLVTKFLFESDFADEPLLPSPLQLRGKILLKNKKLKAHQAPVDILKQKAHQLAHMQAQANNGTVSTTPLGNNDEEEEEEDEYDYDYESLSDDNILDDKPEGKSSTEKLQYESNDEMPKRFKKAGSKGKMFDMELGEEFYLPQNEKESRQIAQELSDLVIYCQAIKFPGLSTLSPSGSGRGKDRKSRKSIFGSAPARGSPGEPVTLVRAPGKASLEGIRMNSEEQMCLSPSTSLSSIIRTPKCYHISSVNENAAKRLCRRYSQKLIQHTSCQLLRTYPAATRIDSANPNPLIFWLHGVQLVALNYQTDDLPMQLNAALFEANGHCGFVLKPPVLWDRSCPLYQHFYPLDRDLENMTPTLYTLTIVSGQNVCPGNSNGSPCVEVEVLGMPADSCHFRTKPIHRNTLNPMWNEHFQFHVHFEDLAFLRIAVVENNSSQVTAQRILPLKTLRAGYRHLQLRNLHNEPLEVSSLFMFSRRTEESPTGGPPSASVLFSTEERRSVQQHKVTVHGVPGPEPFTVICVDEFTTAKQLLDSLFPTASFKYMLMEERVSLSKEKKAPQQRPLANDERLLKLIHSWQPEDGYVGRIYLKTREQQNCSEKTSVPLESLEELGSSEDDTFFVQVHDVSPEQPHTVIKAPRYSTAQDIIQQTLSKAKYSLSILSNPNPCDYVLMEELCKDAGGKKSSSAKPCQRVLQDHECVFQAQSRWKGAGKFILKLKEQLAREDKRKGVSFASELRKLTGRSRSVTVNTNSNDTHSKEEKSACPSMSCVPETSQ
Protein: NOT2/NOT3/NOT5 C-terminal domain-containing protein (Q585G1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- NOT1
- Uncharacterized protein
- Cell differentiation protein, putative
- poly
- Endonuclease/exonuclease/phosphatase, putative
- Endonuclease/exonuclease/phosphatase domain-containing protein
- CCR4-NOT transcription complex subunit 11
- ATP-dependent DEAD/H RNA helicase, putative
- RNasePH-like protein exosome-associated protein 1 Rrp42 homologue
- ATP-dependent DEAD/H RNA helicase, putative
Sequence:
MNNSNQGTRYPGTIPQGIPIAYPAQAGAPNPYQSLRGVFPVTTQALVAQQQQQLQQQQQQQQAQLQQQQQQQQAQLQQQQQQQQAQLQQQQQQQQQQLQQQQQQQAQQQQQQQQPRGRVAVEGPYGLLALPNLIQHPVNAEKSDSAAFLYLTRGFELNSLGINVAQQRPLHPTLASIALERPEVPVIPEYRIPECYKQARPRQPTFRMLQKYKNETLFYIFYSMPRDLLQTVAAKVLVSRGWCFHKARHQWMRRVVQNEYEVFNQNAWKLENEEMHQLNASDLLRDIPDSFLAAPGTTGTGAAAPPPTSTNSNSSGNNNNNNNSSVVGGD
Protein: Probable molybdenum cofactor guanylyltransferase (MoCo guanylyltransferase) (EC 2.7.7.77) (GTP:molybdopterin guanylyltransferase) (Mo-MPT guanylyltransferase) (Molybdopterin guanylyltransferase) (Molybdopterin-guanine dinucleotide synthase) (MGD synthase) (P9WJQ9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00316}.
Interaction partners:
- 2-oxoglutarate oxidoreductase subunit KorB
- 2-oxoglutarate oxidoreductase subunit KorA
- Molybdopterin molybdenumtransferase 2
- Molybdopterin molybdenumtransferase 1
- MobA-like NTP transferase domain-containing protein
- MobA-like NTP transferase domain-containing protein
- VWA domain-containing protein
- Uncharacterized MFS-type transporter Rv2456c
- ATP-dependent Clp protease ATP-binding subunit ClpX
- Uncharacterized protein
Sequence:
MAELAPDTVPLAGVVLAGGESRRMGRDKATLPLPGGTTTLVEHMVGILGQRCAPVFVMAAPGQPLPTLPVPVLRDELPGLGPLPATGRGLRAAAEAGVRLAFVCAVDMPYLTVELIEDLARRAVQTDAEVVLPWDGRNHYLAAVYRTDLADRVDTLVGAGERKMSALVDASDALRIVMADSRPLTNVNSAAGLHAPMQPGR
Protein: Triplex capsid protein 1 (P32888)
Organism: Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Function: Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04018}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04018}.
Interaction partners:
Sequence:
MKTNPLPATPSVWGGSTVELPPTTRDTAGQGLLRRVLRPPISRRDGPGLPRGSGPRRAASTLWLLGLDGTDAPPGALTPNDDTEQALDKILRGTMRGGAALIGSPRHHLTRQVILTDLCQPNADRAGTLLLALRHPADLPHLAHQRAPPGRQTERLGEAWGQLMEATALGSGRAESGCTRAGLVSFNFLVAACAASYDARDAADAVRAHVTANYRGTRVGARLDRFSECLRAMVHTHVFPHEVMRFFGGLVSWVTQDELASVTAVCAGPQEAAHTGHPGRPRSAVILPACAFVDLDAELGLGGPGAAFLYLVFTYRQRRDQELCCVYVIKSQLPPRGLEPALERLFGRLRITNTIHGTEDMTPPAPNRNPDFPLAGLAANPQTPRCSAGQVTNPQFADRLYRWQPDLRGRPTARTCTYAAFAELGMMPEDSPRCLHRTERFGAVSVPVVILEGVVWRPGEWRACA
Protein: Signal transducer and activator of transcription (J3KPM9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
Sequence:
MWMSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEV
Protein: Myotubularin-related protein 12 (Inactive phosphatidylinositol 3-phosphatase 12) (A2BGG1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Acts as an adapter for the myotubularin phosphatase mtm1 to regulate mtm1 protein stability and possibly its intracellular location. By stabilizing mtm1 protein levels, required for skeletal muscle maintenance but not for myogenesis. In skeletal muscle cells, does not regulate mtm1 subcellular localization.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9C0I1}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:Q80TA6}. Cytoplasm, myofibril, sarcomere {ECO:0000250|UniProtKB:Q80TA6}.
Interaction partners:
- Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2
- Myotubularin 1.
- Myotubularin-related protein 14
Sequence:
MLSLGSGGAKSSKPSFVSYVTPEEIKLEKDPQKKEKHPDLLPGEVVFCSANPILKYTQDDLSQRGVFGTLLCTNFRVAFISDDAPQEEMSKTFKNKLYGENDIPLMCVDHIYGVYDEKRKLITGGLVKNKCPSKMIIHCKDLRVFQFCLTFSKEEDAKRIFQGIAHHCLEEKSLKCVFAFSYLRSTNPEMLRKREAIMFDSPEDWTQEMKRTKAQCRLVTENENFELSQRLPQYFVIPSALGDLFNYQGKGLPIWCWSHHSGCALFKASFPSMTQEDGDFQSHLDTMITAVARNYLYSVKTEDLSESLPTLQDIQQSYNKFKQYFLIDNTTDFWLSDVKWFSSLESSGWLDIIRQCLQKAVEVVECLEKDNTNVLITEEEGTDLCCVISSLAQIMLDPYYRTLMGFQSLVQKEWVAGCHAFLDRCNHLHQKDKECHSPVFLLFLECVWQLVQQHSPAFQFSETYLTVLSDSVHVPIFSTFLFNSAHHRESVMKAESPIAQSRPLSCPTVWDWSVQFDSKAQNFFFNPLYSEKVKHERTVRRPHKHKHQRQLSLPSSAFKTPTKKGFFKDETDSLKKMLRVKRISRWMGSPDSPVVASREFYESWQQRPLDYHGLLLPSLDGPSVRIWMQRYLRWIPEVHIMGGGSVAIMTKLMELLSQVEDLKRVLEQRDPSLATQPDHPPPLHHRLPSFGSSGRLSSSFPFTYSRNRSFKPIIPTGLMQSLMVADNLANQEDETS
Protein: Bifunctional chrysanthemol synthase, chloroplastic (Chrysanthemol synthase, chloroplastic) (EC 3.7.1.-) (Chrysanthemyl diphosphate synthase, chloroplastic) (CPPase) (TcCDS) (EC 2.5.1.67) (P0C565)
Organism: Tanacetum cinerariifolium (Dalmatian daisy) (Chrysanthemum cinerariifolium)
Function: Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide. Catalyzes the condensation of two molecules of dimethylallyl diphosphate to produce chrysanthemyl diphosphate (CPP), a monoterpene with a non-head-to-tail or irregular c1'-2-3 linkage between isoprenoid units. In a second step, hydrolyzes the diphosphate moiety of CPP to form chrysanthemol. With a lower efficiency, can also converts dimethylallyl diphosphate into lavandulyl diphosphate (LPP), and subsequently LPP into lavandulol.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:25378387}.
Interaction partners:
Sequence:
MACSSSLSSKWASWGASSRPHPSVQPFVTRKNVVRYHKPTSELSYSPLTTTLSSNLDSQFMQVYETLKSELIHDPSFEFDDDSRQWVERMIDYNVPGGKMVRGYSVVDSYQLLKGEELTEDEAFLACALGWCTEWLQAFILVLDDIMDGSHTRRGQPCWFRLPEVGVVAINDGVLLRNHVHRILKKYFQGKPYYVHLLDLFNETEFQTISGQMIDTICRLAGQKDLSKYTMTLNRRIVQYKGSYYSCYLPIACALLMFGENLEDHVQVKDILVELGMYYQIQNDYLDTFGDPDVFGKTGTDIEECKCSWLIAKALELANEEQKKILSENYGINDPSKVAKVKELYHALDLKGAYEDYETNLYETSMTSIKAHPNIAVQAVLKSCLEKMYKGHK
Protein: Complement component 1 Q subcomponent-binding protein, mitochondrial (I3L3B0)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004296}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004296}; Extracellular side {ECO:0000256|ARBA:ARBA00004296}.
Interaction partners:
Sequence:
MSGGWELELNGTEAKLVRKVAGEKITVTFNINNSIPPTFDGEEEPSQGQKVEEQEPELTSTPNFVVEVIKNDDGKKALVLDCHYPEDEVGQEDEAESDIFSIREVSFQSTGESEWKDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ
Protein: Serine/threonine-protein kinase PBL35 (EC 2.7.11.1) (PBS1-like protein 35) (Receptor-like cytoplasmic kinase PBL35) (Q9SRH7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in chitin-triggered immune signaling and is required for reactive oxygen species (ROS) production. Acts downstream of SD129 in defense signaling triggered by the pathogen-associated molecular pattern (PAMP) 3-OH-C10:0, a medium-chain 3-hydroxy fatty acid.
Subcellular location: Cell membrane {ECO:0000269|PubMed:31922267}; Lipid-anchor {ECO:0000250|UniProtKB:O48814}.
Interaction partners:
- Guanylate kinase 3, chloroplastic
- Guanylate kinase 2
- Guanylate kinase 1
- Vesicle-associated membrane protein 724
Sequence:
MGFDSVKVMENWQSKTSNENEKKKKKRRRKKNNNVRNSEHYEEEANGCWVKFRYIVCCASSTSDVETSLTLSTSTVGSQSAIVQSNDQPVGPVSSTTTTSNAESSLSTPIISEELNIYSHLKKFSFIDLKLATRNFRPESLLGEGGFGCVFKGWVEENGTAPVKPGTGLTVAVKTLNPDGLQGHKEWLAEINYLGNLLHPNLVKLVGYCIEDDQRLLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLHEEALKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEGKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDPRLEGHFSVKGAQKVTQLAAQCLSRDSKIRPKMSEVVEVLKPLPHLKDMASASYYFQTMQAERLKAGSGSGSGRGFGSRNGQPVFRTLSSPHGQAGSSPYRHQIPSPKPKGATT
Protein: Olfactory receptor 1A1 (Olfactory receptor 17-7) (OR17-7) (Olfactory receptor OR17-11) (Q9P1Q5)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
Sequence:
MRENNQSSTLEFILLGVTGQQEQEDFFYILFLFIYPITLIGNLLIVLAICSDVRLHNPMYFLLANLSLVDIFFSSVTIPKMLANHLLGSKSISFGGCLTQMYFMIALGNTDSYILAAMAYDRAVAISRPLHYTTIMSPRSCIWLIAGSWVIGNANALPHTLLTASLSFCGNQEVANFYCDITPLLKLSCSDIHFHVKMMYLGVGIFSVPLLCIIVSYIRVFSTVFQVPSTKGVLKAFSTCGSHLTVVSLYYGTVMGTYFRPLTNYSLKDAVITVMYTAVTPMLNPFIYSLRNRDMKAALRKLFNKRISS
Protein: Paired box protein 1 homolog (Q21272)
Organism: Caenorhabditis elegans
Function: Transcription factor (By similarity). May play a role in pharyngeal cell differentiation (Probable). May have a protective role in response to infection by the Gram-negative bacterium Vibrio cholerae.
Subcellular location: Nucleus {ECO:0000269|PubMed:20714352}.
Interaction partners:
- LRRCT domain-containing protein
- Uncharacterized protein R07B1.9
- AT-rich interactive domain-containing protein arid-1
- Nuclear receptor domain-containing protein
- Uncharacterized protein
Sequence:
MNCDTAQPWMMSSYHPSTTSDVFWTTTPSSTSTTPSSDNGIQQYSSISTSSGYAPANSPAKTAEVNQLGGVFVNGRPLPFEMRCKIVELSRQGTRPCDISRQLKISHGCVSKILTRFSENGTIMPGTIGGSRPRVTTPKVVEYIRSLKRSDPGIFAWEIRDRLISADICDRANLPSVSSISRILRNKNGGNSSSSSSSQLRYIRDQLAEQQQQQHLQQHQYMEYNNNELNQISGNLDYQVSSSNTPPSYDSYHFIAN
Protein: Neuronal acetylcholine receptor subunit beta-2 (Neuronal acetylcholine receptor non-alpha-1 chain) (N-alpha 1) (P12390)
Organism: Rattus norvegicus (Rat)
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.
Subcellular location: Synaptic cell membrane {ECO:0000269|PubMed:21325521}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P17787}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Neuronal acetylcholine receptor subunit alpha-4
- Acetylcholine receptor subunit alpha
- Neuronal acetylcholine receptor subunit alpha-5
- Neuronal acetylcholine receptor subunit beta-4
- Neuronal acetylcholine receptor subunit beta-3
- Neuronal acetylcholine receptor subunit alpha-9
- Acetylcholine receptor subunit delta
- Neuronal acetylcholine receptor subunit alpha-3
- Acetylcholine receptor subunit epsilon
- Acetylcholine receptor subunit beta
Sequence:
MAGHSNSMALFSFSLLWLCSGVLGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSDVASLDDFTPSGEWDIIALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFLQQPRHRCARQRLRLRRRQREREGAGALFFREGPAADPCTCFVNPASVQGLAGAFRAEPTAAGPGRSVGPCSCGLREAVDGVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTVGMFLQPLFQNYTATTFLHPDHSAPSSK
Protein: Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Q9UT61)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Degrades free oligosaccharides in the vacuole.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Vacuole {ECO:0000250}.
Interaction partners:
- Autophagy receptor Nbr1
- Aspartyl aminopeptidase 1
Sequence:
MTLFPVLNNTPVGKQVDSIYESRLDQFLSEGQYRDFNLPSVYDHARIDNPSGDVNNDLSKGFVDLKVYRVPDLSRPSFNEVVGHKKFDETASKGDTFGPSWATFWFEVHIRLPKSWAKYEQVIFQWNCDNEGLVYSQDGVPLQAFSGSERTDFILPDSWKTTEDTFYIEMACNGMFGTGAGSQIAPPDPNRYFTLTKADLVAPNLPAMALAYDFLLMQQCVKQLPSNCWQKYKARQICNDIMNTFHPNDLSTINECRNLAKAFLGNDIDSEAVFEKNNDKANVFAIGHCHIDTAWLWPFAETRRKIVRSWATQMNIMDRYPEYQFVCSQALQYLWLKEDHPDVFEKLKEYVNQNKFIPIGGSWVEHDTNIPNGESLIRQFLLGQHFFEKEFGVRCRTFWLPDTFGYSSQIPQICRLCGMDRFLTQKLSWNNINSFPTSTFNWVALDGSQVICHMPPANTYTADTNVNDVLHSIDQHKNLVNDQAGLLVFGIGDGGGGPTPEMLEKLRRCKGIANTVGYLPNVKLGNTVDEFFDGILKRTNAGQTLPSWNGELYFEFHRGTYTTQAELKKLMRKVEIALHDAEYVSTLASIFSKDYSYPKESLQDLWRDTLLCQFHDVLPGSCIEMVYKDAIPIMSKVLKNTEALLWQAIEQLGFKKASSSDNKEQLCLLNTLPWNVRGVITETEENKLVYFESCDGKGILTAAHTSLKHPAAAYQKDDNFILVNDHLRVTIAPNGLILSLFDLHKEREILDLKSGKNHAGANQYVLFEDTPLSWQAWDTEVFSLEKYEVLDKGKVSIKESGPLRASVVVDIPISELSHMKATISLEGYNDCSEFTGVNFTCEVDWHESCKFLKVEFPVDIHSEFASYETQFGITKRPTHYNTSWDVAKFEVCHQKFADYSDFTYGVSVLNDCKYGFSTHGNLMRLSLLRSPKQPDAHADMGKHTIRYAVYPHSKPLDSSTVRAAHKFNSNFRLLTRASDTANLDIFDAFQLVGEPNVILSHIKMAEKGKSIILRVYESLGGKSRARLVIKSLTVASVTKCNGLEEDLEELCTLKSNDYYEVPIELRAFEIATFKVNL
Protein: Conorfamide-Sr2 (CNF-Sr2) (Cono-RFamide-Sr2) (P85871)
Organism: Conus spurius (Alphabet cone)
Function: In contrast to other conorfamides, this peptide does not show activity on human and mouse sensory neuron-specific G-protein coupled receptors MRGPRX1. In vivo, it causes hyperactivity when injected intracranially into mice, and when injected into the foot of the fresh water snail P.paludosa. It also causes paralysis when injected into the foot of the limpet P.opea. Has no effect when injected below the rear part of the dorsal fin of the fish L.reticulatus.
Subcellular location: Secreted {ECO:0000269|PubMed:18201803}.
Interaction partners:
Sequence:
GPMEDPLEIIRI
Protein: GH08833p (Q95U43)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRASTHGLVINIIHSLCTCTNPSFSEEAQRVLRLSLDEFSLPKFYLLFGISKVKSAAVTAFRSSCRHPTDKWLGNERVTQPLPADRERLSLPSLEVITDALLEIMEACMRDVPDCEWLNTWTSLARSFAFCYNPALQPRALIVYGCISKSVTDHEVKQLLRILVKALESFNDLILIEALVMCLTRIQPLLRPESPIHRALFWVAISVLQLDEITLYGAGLALLEQNLHTLKSQGCFDKKETIAEVMMKTREKLEWHFKQLDHAVGLSFRSNFHFALVGHLIKGFRHPTPTTVSRTSRVLTMLLGIIAKPLHRDKFEVTPDSVAYLTALVAVSEEVRSRCHVKHALPRWPADLSSSVENGEASGGVQAIGLPLSRRQKSWDILDQSALQFARQHKVPTLQERGSRSSVSNESNVLLDPEVLPDLSIQALVLTVLATLVKYSSDEGETRVLYQYLAEGSVVFPKVFPVIHSLLDQKINNILSVSHDQVVLNSVQNIIQNMLASEDPSQQQLHFLQSCGFGGLWRFAGPFTKYNMMGESSELFVNCLEAMVETCLPGDESAPVPPSPRPYNLSSSLSSLTLGSPTDKECPEAMTTECERRK