wanglab/gogpt-training-data huggingface dataset:
Protein: Centrosomal protein 135kDa, isoform A (LD35990p) (Q960T6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}.
Interaction partners:
Sequence:
MNINDGDFKDLRCKLDIMGFTQTLPVLAIPLVQAVFGDLIKTTECLRDTKKKVAELLEEKTCWELGVEPYKCDNSRLLAECNELHLQFLRDREDYELRLCESERKIRNLELDKQHLQSHNDGLQRQLDALLTKQMVSSVTNKKATAGIGRQTKKPFITTVRSGIAMPTTLGTSSSALKCTKCNAGVFQKTTTTTKDGVTVTQTSGQEELDKMQNDLTAAGEQLEFFKRKVEARNREIRRLNDMLAGGRPLAALAKDCCYKDVGALSQDIDLLQREKSDLMMQVREFQDKMHDAMQRALSSEEDKIKLQTQLEELKEAALQVEQQANAEIDAKESELRQLQLELKKKGKDHRLTGGFASNQSDKHNLNERLNLLTRREEELQATNEKHKKKIQKMQAKILELQKELKDQNKHSNVTLDEEKIRLSSERDFFQKEYLRLMSKTGSESEIAFLHAQIKSKDEELKALRSELFHGGKQQFSPQKSVQYETLPPPTASSITSTVTSNTSDCVQAAIARVERERDCARTELERVRCERDTLREKQLSTVQLHADELQALRLRNEELNDRLRQMERDNRELNSARLPTETNLVLLKEDLLQMRQRVASMQTEIDQLKTENDQITMLNDQNERIIADYQSKLLVAERQRQSADVRASTLDSSRESNRSEVTQLRMDLGALRQTYISLEHEKDTLLHQLDTKTERVYKLEYELKDCKEKRNALEQNVKDLEDQLRKLANRNRQRDSELTETSTESKTLRQQIVALKASRDEAIAENRRLMDKLSDAQVEARTLQKKLTDSELQVANMKQQLHKYVQEVKKAEDLLIQKEKERDDMLDQYHCLTQGQATLEGNNQSLECEAVEFRRQICELECEVHSLKEQLQLRQCALHDMEVQLTAARASVRCLERELENARDDIRVQKVDLEARKELCDKLDVERSKLNAELNDVNEIRKKLEKQCEKLRDELQQSLAINQVTNETTDLMLGRLHNDQQHQEDDDIRSKHEMDRLQRQLQQTLDQLQEERVRCRHHEELAEKWEQQVRDLRRNLADDRYNQARTREVSPRVPSKTL
Protein: GH09216p (Q8MSJ3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGARGKTAQEMRDVLKLPDDKKEVAAKFKDLLSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITASIVNKWVDTQTSGKIRDLVMPSDVANLVLVILNAIYFKGQWQKKFNTEQTKSDFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKVDGLPELEKKMVGFTPKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRDAENIYFQGHFVNPEL
Protein: Large ribosomal subunit protein uL14m (39S ribosomal protein L14, mitochondrial) (Q9W4Z2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Small ribosomal subunit protein uS12m
- Large ribosomal subunit protein bL20m
- Small ribosomal subunit protein bS16m
- Ribosomal protein
- Large ribosomal subunit protein mL54
- IP05433p
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein uL16m
- Large ribosomal subunit protein mL52
- Small ribosomal subunit protein mS29
Sequence:
MALRILKTVRQVAQPLAVTLGGQQTQQLIHTTPACCEIRKLARLRVVDNSDLGKKAMAEGRPPRCIHVYNKRGVGFIGDKVLVAIKGQMKKGILVGLKQNQKPKQPKFDSNNLVLIDDNGSPLGTRIHVPIPTILRTILKEKTLAKGADYTKVLAIASRYV
Protein: Ly6 domain-containing, pigment cell (Lypc) (Sperm acrosome membrane-associated protein 4-like precursor) (X1WGJ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Transmembrane protein 244
- tRNA pseudouridine synthase.
- Transmembrane protein 141
Sequence:
MAYVLRCILFLYLLPSVVPLLCYTCVFPSISPLDCLKFPTKCSLGQVCLSSKAVARRGDLEIHFYEKSCALPALCGLTGEKFIQGLNFTFRSDCCDTLLCNHSTANSAFVWPSILLSLLFTLFYSQ
Protein: Programmed cell death protein 2-like (Q9BRP1)
Organism: Homo sapiens (Human)
Function: Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase.
Interaction partners:
- Protein arginine N-methyltransferase 3
- Small ribosomal subunit protein uS5
Sequence:
MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRPVCQRCGQPLALVVQVYCPLEGSPFHRLLHVFACACPGCSTGGARSWKVFRSQCLQVPEREAQDAQKQGNSLAAEDWCEGADDWGSDTEEGPSPQFTLDFGNDASSAKDVDWTARLQDLRLQDAVLGAAHPVPPGLPLFLPYYICVADEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSQCGGQRIFEFQLMPALVSMLKSANLGLSVEFGTILVYTCEKSCWPPNHQTPMEEFCIIQEDPDELLFK
Protein: Proline/serine-rich coiled-coil 2, isoform CRA_a (Zinc finger C3H1-type containing) (G3V1X1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATADTPAPASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHSARGGGSGGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVRMPSSSLSESSPRPSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPLGGGAGSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGIPYRVKEGFTPIPGLKFSA
Protein: 2-acylglycerol O-acyltransferase 2 (EC 2.3.1.20) (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 1-like) (Monoacylglycerol O-acyltransferase 2) (Q80W94)
Organism: Mus musculus (Mouse)
Function: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity. Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14966132}; Multi-pass membrane protein {ECO:0000269|PubMed:14966132}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q3SYC2}.
Interaction partners:
- Diacylglycerol O-acyltransferase 1
- Phosphatidate phosphatase LPIN2
- Monoglyceride lipase
- Phosphatidate phosphatase LPIN1
- Patatin-like phospholipase domain-containing protein 2
- Phosphatidate phosphatase LPIN3
- Diacylglycerol O-acyltransferase 2
- Phospholipid phosphatase 2
- Pancreatic triacylglycerol lipase
- 1-acylglycerol-3-phosphate O-acyltransferase Pnpla3
Sequence:
MVEFAPLLVPWERRLQTFAVLQWVFSFLALAQLCIVIFVGLLFTRFWLFSVLYATWWYLDWDKPRQGGRPIQFFRRLAIWKYMKDYFPVSLVKTAELDPSRNYIAGFHPHGVLAAGAFLNLCTESTGFTSLFPGIRSYLMMLTVWFRAPFFRDYIMSGGLVSSEKVSADHILSRKGGGNLLAIIVGGAQEALDARPGAYRLLLKNRKGFIRLALMHGAALVPIFSFGENNLFNQVENTPGTWLRWIQNRLQKIMGISLPLFHGRGVFQYSFGLMPFRQPITTIVGKPIEVQMTPQPSREEVDRLHQRYIKELCKLFEEHKLKFNVPEDQHLEFC
Protein: 45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4) (Q91ZS3)
Organism: Rattus norvegicus (Rat)
Function: A membrane-associated isoform may be involved in the exocytosis of zymogens by pancreatic acini. May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Subcellular location: Golgi apparatus lumen {ECO:0000250|UniProtKB:Q61112}.
Interaction partners:
- Calbindin
- Parvalbumin alpha
- Calretinin
- Calmodulin-1
- Calmodulin-like protein 4
- Calmodulin-like protein 3
- Protein S100-G
- Protein S100-B
Sequence:
MVWLVAMTSRQRSLCGLAAHGLWFLGLVLLMDATARPANHSFSRERAANRDENEIIPPDHLNGVKLEMDGHLNKDFHQEVFLGKDMDGFDEDSEPRRSRRKLMVIFSKVDVNTDRRISAKEMQHWIMEKTAEHFQEAVKENKLHFRAVDPDGDGHVSWDEYKVKFLASKGHNEREIADAIKNHEELKVDEETQEVLGNLRDRWYQADNPPADLLLTEDEFLSFLHPEHSRGMLKFMVKEIVRDLDQDGDKQLSLPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTMEELENYMDPMNEYNALNEAKQMIAIADENQNHHLEPEEILKYSEFFTGSKLMDYARNVHEEF
Protein: AT-rich interactive domain-containing protein 3B (ARID domain-containing protein 3B) (Bright and dead ringer protein) (Bright-like protein) (Q9Z1N7)
Organism: Mus musculus (Mouse)
Function: Transcription factor involved in the production of cranial mesenchymal tissues. Favors nuclear targeting of ARID3A.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355}.
Interaction partners:
- POU domain, class 5, transcription factor 1
Sequence:
MEPLQQQQQQQQQKQPQQPLLQMDAREKQGPQTRESQFLYASKLGTQPALLSITPGRPSGSSVLGPLARVPPATPVARMSEQSNVNSEPEEEEGGLEDEDGDDDVAEVAEKEAQAASKYFHMQKVTRQEPRATPMSSLLPVPGLSPQGQQTKEDHTKDASKAPPSVPTAGQPSWSLDEQLKQNGALAWSDDADGGRGREISRDFAKLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPAAAAAAAAAAAAAAASAASAGTPALLSSPKIRFSILGLGSSSGTSASSPRIPPASTLRKGDGVPVPVPNRLAVSGTLAGQQAGNRPGPLEHLRERLESGEPPEKKASRLSEEEQRLVQQAFQRNLFSMARQLPMKIRINGREDRAEPSAPALNLTTSNIGSINMSVDIDGTTYTGVLFAQKPVVHLIAGSTPQSIGSSASSSNSSSSHCSPSPTSSRGTPSAEPSTSWSL
Protein: Ground-like domain-containing protein (Q9XV14)
Organism: Caenorhabditis elegans
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Interaction partners:
- Ground-like domain-containing protein
- DUF229 domain-containing protein
- Ground-like domain-containing protein
- Uncharacterized protein R07B1.5
- Uncharacterized protein
- Ground-like domain-containing protein
- Methyltransferase FkbM domain-containing protein
- Ground-like domain-containing protein
- Ground-like domain-containing protein
- Ground-like domain-containing protein
Sequence:
MKFPTFLLFYFTGFLGGYQVDAVCIWNRTQSWTVPYQSILVECCDKPLKQLILDTIHGTNFESLANGDFAKIVQRRAQMEFHSSFETIVSKTNFAISSHYHGPHTCRVHKKGHYLLVYETPVQYDPYNLPIENYLASIDSSDPLGSTKPFGLRGDFPDISDDPTAGDDLSIQPPSDQILQFPNKFAWPDPDDGTHEPSNKIKRADFDEEVDDLMEISVMDSNSNSTHLEEDLKKEFASKFNTDLDRPGPQPVPRNITNWRKKERYPKGTHCESGKRDGNKCCDARLAATMRDAMRQMATSPEFGPGKEGIVAAELQQSVQTRFKKSYEIIVSRSDFVATTYTAGEKFCKFKTKNFVILAYVTPRQYDIDKKDDERILADVSNRDPLGSSETKFPDEEPFHKELQLEESGDRAGYPVGSHCSNDTRTGSKCCNLRLFNAMKDGYDRHKASPNFDRYNIRNISKAIQWSVEEVFQHSAEVFVSLDDFAYATNEKNEESCKYRVDKYYVYVYTTPVPYPIHQPTYNDIGSAKPFHCPPDLSGLDGTACCNSGLQYEINRILDEARYSDSYHKHDTRYLAKMITRAVQRRFNTTFETIVAEADFSWSTNKFTGRMCKIDHEGYNALTYQSSLRPPRAIDFIDFPNDVTLDGPTFVENGWFGNGNGALSAQAQVVVQAQIAAQAVAPPQPPVFVQQFVAPQFVQFVAPQPQFVAVAPQPQFVAVAPVPPPVAPAVAFAGGGGGGGGCFSSDTLVTTPSGKKRMDEIDVGDYVLTANRVKTHFTPVTLWIHRESEKLEEFLTITTERGSTLQLTPLHFMYRTKCNESSEFLKILPENHEAILASYLEIGDCVILTENTKFRQEKINQTTRGLKTGIYSPLTKNGRIIVNDMLASCYSEVQANVLQTTYFWVFNRLRQKVLNLFGILHMNEIELPTGTAVYKELLSLVIPMGK
Protein: Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (EC 3.1.3.80) (2,3-bisphosphoglycerate 3-phosphatase) (Q941B2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
- Inositol-tetrakisphosphate 1-kinase 2
- Inositol-tetrakisphosphate 1-kinase 3
- Inositol-tetrakisphosphate 1-kinase 1
- Inositol polyphosphate multikinase beta
- Inositol polyphosphate multikinase alpha
- Inositol 1,3,4-trisphosphate 5/6-kinase 4
- Type I inositol polyphosphate 5-phosphatase 1
- Type I inositol polyphosphate 5-phosphatase 2
- Phosphoinositide phospholipase C 7
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1
Sequence:
MATKTVWIILLCLFVVSQADQGFDVRHHLSTVTRYSTSKDVTQNLIEGSNVPSECTPIHLNLVARHGTRSPTKKRLRELESLAGRFKELVRDAEARKLPSDKIPGWLGQWKSPWEGKVKGGELIRQGEDELYQLGIRVRERFPSLFEEDYHPDVYTIRATQIPRASASAVAFGMGLFSEKGNLGPGRNRAFAVTSENRASDTKLRFFECCQNYKSYRKAKEPAVDKLKEPVLNKITASVAKRYDLKFTKQDISSLWFLCKQEASLLNVTNQSCELFTPSEVALLEWTDDLEVFLLKGYGNSLNYKMGVPLLEDVLHSMEEAIKAREEKLPPGSYEKARLRFAHAETIVPFSCLLGLFLDGSEFEKIQKEKPLELPPQPPKTRDFRGSTMAPFGGNNILVLYSCPAESSPKYFVQVLHNEHPIAVPGCDGKDFCPLEDFKAKVVTPHLKHAFDNLCNADLNDLKQKPASSKLSILSSWLFGSSHDTEL
Protein: Threonine synthase (TS) (EC 4.2.3.1) (P9WG59)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
Interaction partners:
- Homoserine kinase
- Homoserine dehydrogenase
- L-threonine dehydratase biosynthetic IlvA
- Phosphoserine aminotransferase
- Diaminopimelate decarboxylase
- Arginine--tRNA ligase
- Aspartokinase
- 3-isopropylmalate dehydratase small subunit
- Ketol-acid reductoisomerase
- Glutamate synthase large chain
Sequence:
MTVPPTATHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDTALKDMPSVSPVPVDPVAVVEKLGLA
Protein: Probable cysteine protease RDL3 (EC 3.4.22.-) (Probable cysteine proteinase At3g43960) (RD21A-like protease 3) (Q9LXW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable thiol protease.
Interaction partners:
- UPF0235 protein At5g63440
- At2g34910
- Bifunctional protein FolD 2
Sequence:
MAISFRTLALLTLSVLLISISLGVVTATESQRNEGEVLTMYEQWLVENGKNYNGLGEKERRFKIFKDNLKRIEEHNSDPNRSYERGLNKFSDLTADEFQASYLGGKMEKKSLSDVAERYQYKEGDVLPDEVDWRERGAVVPRVKRQGECGSCWAFAATGAVEGINQITTGELVSLSEQELIDCDRGNDNFGCAGGGAVWAFEFIKENGGIVSDEVYGYTGEDTAACKAIEMKTTRVVTINGHEVVPVNDEMSLKKAVAYQPISVMISAANMSDYKSGVYKGACSNLWGDHNVLIVGYGTSSDEGDYWLIRNSWGPEWGEGGYLRLQRNFHEPTGKCAVAVAPVYPIKSNSSSHLLSPSVFKLVVLFVFQLISLALL
Protein: RNA-binding protein, putative (Q38BP9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Branch point binding protein, putative
- Splicing factor 3B subunit 1, putative
- U2 splicing auxiliary factor, putative
- Cell division control protein, putative
- Sm protein G
- Spliceosome-associated protein, putative
- Sm protein F
- Small nuclear ribonucleoprotein Sm D2
- PHD finger-like domain-containing protein 5A
- Uncharacterized protein
Sequence:
MGRDSRGDRYGRRDDVVDPHGGSRGGGEASSSRYSRYARTKRSRSPRGGRRNSSEERKHRRRRSESVSRQRRRREVSGDSGKKGHRRSRSRSRSRSRSKPSSRRKEGGELSRFKTVDVNELLQSPTPDPSAVPSNSLQTQILFQLLQQQQQHAGLLSDPLPAAVAIPPVETTPMISVGTVAGAVQSAYPLQTDGEVPQETLIDQPAPAKVLPSVADFVPVIPKSLVGLLTTPATGSNVESGGADVSAASGGGANGGTCGVLTTATGALAVLQAPKLSPEAERRAREARRAHISCFPRGTTQQELLDYFRTIIPIVRRIRVQREMDRLTEEARAKLGNDAEAENIERREIPPNAVIDVDRVIDLAVNSAKSKPFGFLEVSLADLVTELVEESVRDPDRFTFVAADGKPYPITIRRPRDYQELPGVDHRKVVMLGFPPTLPLEKLRLVFEQFGQLLAFDVKEGMAYGEFEKEEDAVECVRDLQGEVLGNRVVVLMPLYDWLKVVCTHADIDVSLDPDDPVAGTSLLAKTNQNDGAIVPLLAEDVEKKEEPVDHMKELLELTVHLPDVILHFSKTFPHLRSLYGSTVPIFPTRILVLMNLFDEEELVLDETYERLVEEVSEEVEKHGRVKSLIIPRRTPPPLPPKLPKNVLASRTGATKNSEMGQPKHSQNDDSDGSRKDYEFAADPTAPPMPSNISVGREDVQSFRGDNDGIKHDQGDGSNLNTNNDSINDDEDEEAKYEREKAEYLKAREAYTENILHPIHGGLGRVFVEYESVDEAAIAQREIAGRLFGGRTVVTSFMFEDVLYPPTTEEEEARAEEKVQLYLESIGAGDGDEGENVGNGEAQPHGGTEDGTQTGAFEEGQNLPLKTEGDDGIAGIDG
Protein: Solute carrier family 12 member 10, tandem duplicate 2 (Q1L963)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Sodium/hydrogen exchanger
- Cleavage and polyadenylation-specific factor 4.
- Chloride channel 2c
- Transient receptor potential cation channel subfamily V member 6 isoform X1
- Forkhead box I3a.
- Prolactin receptor
- Sodium/potassium-transporting ATPase subunit alpha.
- Sodium/potassium-transporting ATPase subunit alpha.
- Anion exchange protein.
- Sodium/potassium-transporting ATPase subunit beta
Sequence:
MAKYIERIRNVIPGMRRRDSNVPHQGDVAVDMGEADFGKKENQKMSIYNPLDPVPKYDFYAKDTWAGRIKKSRPSLDVLRNPPDDITPTPDEEDGRPKVKLVRFGWVLGVWIRCMLNIWGVIMYLRLPWVTSQAGLVLTFVIIFMSVTITTITATSVSAISTNGKVYSGGTYFMISRSLGPELGAPIGLLFAFACSIACALHTVGFSETVRDMLKDFKSQMVDDVNDVRIIGAITVTICLLITFAGMAWEAKAQILFFIAIILSLLNYFVGTVIPPTQEKEAVGFFGYHSDIFVSNLLPSFRGPSGSFLVVFAIFFPACTGILSGVNICGDLKDPTGGIPKGTLLSILCTTLSYLLIAATCAATVVRDASGNKNDSLAISNYTIHCSGLGCKYGWNFDSCEQYRNCTQGLANNLRILTVVSGWGILITIGTFAATLSSALGFLVSAPKVFQLLCKDKIYPYIGFFGKGYGKNKEPLRAYVLTFIIAMCFILIGNLNTIAPLISNFFLASYGLINFSCFHASITKSPGWRPQYRYYSPWLSLFCCCLSFTLMFLFTWWAALVTFSVVLFLIGYVNYKKTYVNWGSSYQAAFYNMALNFSMNLTTVPDHVKNFRPQCLVLSGPPNTRPALVDFVGTFTKNVSLMICGNITIEGEQSDFPEHSSDLVVEWLTKRKVRSFYTTFAAESLQDGAHNLMLASGLGKLKPNTLVLGYKTNWQECKPESLQDYINTINDAFDSNYGVALLRMMDKLDITDDMYSAEDGLSAIDNPAFERDEVPQSRSDTIDRDSDNSDEESSDQIRTVFQAKQGKKTIDIYWISDDGGLTLLVPYLLTRRNRWKKSKIRVFILGDQETKKEDRDDMKMLLKRFRLEIEEVIVITDVDKPPLAKNVQRFEDTITPFRLSEEQTRVDLQEFRRLNPWAVSDKDLEAVRPKVERTVRLNEIIKKNSLYAALVVVSLPVPDLNCPSSLYMAWMDALSIGINCPALLIRGNQENVMTFYCQ
Protein: FI20175p1 (Q9VNT9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- O-acyltransferase
- sphingosine kinase
- Sphingosine-1-phosphate lyase
- sphingosine kinase
- LD18904p
- 3-dehydrosphinganine reductase
- Phosphatidate cytidylyltransferase, photoreceptor-specific
- Neutral ceramidase
- Alkaline ceramidase
- GH11618p
Sequence:
MRDAPEDQSVTVSMPASASGSAAGSTGPSSDRRMTQRLLVELLVVVVLVIPICVYEFAVDPVRRGFFCDDESISYPFQDNTITPVMLGLIVGLLPALVMVVVEYVSHLRAGDISATVDLLGWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKYTIGRLRPHFLAVCQPQIADGSMCSDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGHSSLAFYAMIYVALYLQRKITWRGSKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVAGALITAHYIARMFDDGASNILSGGLRRENTAATLQEEVCPTTPPPYSVNNSFSEDQYCSKV
Protein: G2/mitotic-specific cyclin cdc13 (P10815)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the cdc2 protein kinase to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis. Involved in the reorganization of the cytoskeleton on transition from G2 to mitosis. Association with rum1 promotes its proteolysis during G1. Also essential for initiation of meiosis II.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:2534559}. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Cyclin-dependent kinase 1
- Mitosis inhibitor protein kinase wee1
- WD repeat-containing protein srw1
- M-phase inducer phosphatase
- Cyclin-dependent kinase inhibitor rum1
- G2/mitotic-specific cyclin cig2
- Cyclin-dependent kinases regulatory subunit
- Cell division control protein 18
- WD repeat-containing protein slp1
- Meiotic fizzy-related protein 1
Sequence:
MTTRRLTRQHLLANTLGNNDENHPSNHIARAKSSLHSSENSLVNGKKATVSSTNVPKKRHALDDVSNFHNKEGVPLASKNTNVRHTTASVSTRRALEEKSIIPATDDEPASKKRRQPSVFNSSVPSLPQHLSTKSHSVSTHGVDAFHKDQATIPKKLKKDVDERVVSKDIPKLHRDSVESPESQDWDDLDAEDWADPLMVSEYVVDIFEYLNELEIETMPSPTYMDRQKELAWKMRGILTDWLIEVHSRFRLLPETLFLAVNIIDRFLSLRVCSLNKLQLVGIAALFIASKYEEVMCPSVQNFVYMADGGYDEEEILQAERYILRVLEFNLAYPNPMNFLRRISKADFYDIQTRTVAKYLVEIGLLDHKLLPYPPSQQCAAAMYLAREMLGRGPWNRNLVHYSGYEEYQLISVVKKMINYLQKPVQHEAFFKKYASKKFMKASLFVRDWIKKNSIPLGDDADEDYTFHKQKRIQHDMKDEEW
Protein: TGF-beta receptor type-1 (EC 2.7.11.30) (Transforming growth factor-beta receptor type I) (Q06900)
Organism: Gallus gallus (Chicken)
Subcellular location: Cell junction, tight junction {ECO:0000256|ARBA:ARBA00004435}. Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Cell surface {ECO:0000256|ARBA:ARBA00004241}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
Interaction partners:
- Transforming growth factor beta-1 proprotein
- Transforming growth factor beta-3 proprotein
- TGF-beta receptor type-2
- Transforming growth factor beta-2 proprotein
- Mothers against decapentaplegic homolog
- Mothers against decapentaplegic homolog 3
- Growth differentiation factor 11.
- peptidylprolyl isomerase
- Mothers against decapentaplegic homolog
- Growth/differentiation factor 8
Sequence:
MALRGTRRLRALLRLLVAAVLLPRAAALQCYCHLCTKDNFTCVTDGLCFTSVTRTADRVIRNSMCIAEIDLIPRDRPFICAPSFRDGVTTLPHCCDRDHCNKIELPIPTPGPTPGRPASSLGPVELAAVIAGPVCFVCISLMLILYLCHNRTVIHHRVPSEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM
Protein: Aminopeptidase N (EC 3.4.11.2) (B4DPH5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLMDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK
Protein: EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP) (Q5THR3)
Organism: Homo sapiens (Human)
Function: Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (Probable).
Subcellular location: Nucleus {ECO:0000269|PubMed:12612053}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q6P1E8}.
Interaction partners:
- Parkinson disease protein 7
- Tektin bundle-interacting protein 1
- Dynein axonemal intermediate chain 1
- Tektin-2
- EF-hand domain-containing family member C2
- Androgen receptor
Sequence:
MCKMAIIPDWLRSHPHTRKFTHSRPHSSPCRVYSRNGSPNKFRSSSTTAVANPTLSSLDVKRILFQKITDRGDELQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSRFGGIDLYINGIKRGGGNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFELIDVNKTGLVRPQELRRVLETFCMKLRDEEYEKFSKHYNIHKDTAVDYNVFLKNLSINNDLNLRYCMGNQEVSLENQQAKNSKKERLLGSASSEDIWRNYSLDEIERNFCLQLSKSYEKVEKALSAGDPCKGGYVSFNYLKIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQGLQVSSKGPLTKRNSINSRNESHKENIITKLFRHTEDHSASLKKALLIINTKPDGPITREEFRYILNCMAVKLSDSEFKELMQMLDPGDTGVVNTSMFIDLIEENCRMRKTSPCTDAKTPFLLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGRIGRNNFKKIMHVFCPFLTNAHFIKLCSKIQDIGSGRILYKKLLACIGIDGPPTVSPVLVPKDQLLSEHLQKDEQQQPDLSERTKLTEDKTTLTKKMTTEEVIEKFKKCIQQQDPAFKKRFLDFSKEPNGKINVHDFKKVLEDTGMPMDDDQYALLTTKIGFEKEGMSYLDFAAGFEDPPMRGPETTPPQPPTPSKSYVNSHFITAEECLKLFPRRLKESFRDPYSAFFKTDADRDGIINMHDLHRLLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRTDEAPQRLIRPKQKVADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHITYQEFLQKLGINYSPAVHRPCAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKSTGAQPKEKEESMPINFATLNPQEAVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDFCYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWAEKMPKGPPPTSPKATADRDILARLHKAVTSHYHAITQEFENFDTMKTNTISREEFRAICNRRVQILTDEQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMATGDSAVAQRGSSVPDVSEGTRSALSLPTQELRPGSKSQSHPCTPASTTVIPGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISKEECQQLIIKYDLKSNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETPSFYSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLRAFLQ