wanglab/gogpt-training-data huggingface dataset:
Protein: ATG8-interacting protein 1 (O82775)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in a special stress-induced plastid-to-vacuole protein trafficking pathway. Interacts with ATG8F in plastid bodies to subsequently enable their delivery to the vacuole by an autophagic pathway. Interacts with the plastid proteins APE1 and PSBS/NPQ4 and may recruit them as cargo into plastid bodies that may be recognized by the autophagy machinery for degradation in the vacuole. Involved in the alleviation of damage caused by salt stress during plant development, probably through its involvement in plastid-to-vacuole and ER-to-vacuole trafficking. Plays a role in seed germination in response to exogenous abscisic acid (ABA) treatment.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:22253227}; Single-pass membrane protein {ECO:0000255}. Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. Plastid, chloroplast membrane {ECO:0000269|PubMed:25281689}. Note=Under favorable growth conditions, partially associated with the endoplasmic reticulum (ER) membrane network. Upon exposure to carbon starvation, mainly associated with newly identified spherical compartments that dynamically move along the ER network and reach the lytic vacuole (PubMed:22253227). Under carbon starvation, salt stress and during senescence, localized to novel plastid-associated bodies that are transported to vesicles. These plastid bodises are morphologically distinct from the ER-associated bodies (PubMed:25281689). {ECO:0000269|PubMed:22253227, ECO:0000269|PubMed:25281689}.
Interaction partners:
- Autophagy-related protein 8f
- Translocator protein homolog
- Protein NBR1 homolog
- Ubiquitin-like modifier-activating enzyme atg7
- Ubiquitin domain-containing protein DSK2b
- Autophagy-related protein 11
- Autophagy-related protein 9
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- Cytochrome c-type biogenesis protein CcmE homolog, mitochondrial
- Autophagy-related protein 8e
Sequence:
MANNEEHPPRGNEWEVVSLTSSAYAAAPGPYNVESRDVRKYDAYYGAETSRDLYMSEHFVFPPSEHENLPIDESLFVAEQRKDGRDLMLEGQGLSDQFHYEAGNNQQSIYGESALGSSRHMESFGSESAVYEHGLVDAEGNLDLHSDGEGEKDVKKSTHNLPCEAWWKRRAISMYSRTREANAIWSLFFAAAVTGLVVLGQRWQQERWQVLQLKWQSSISSEKLGRVLEPLSRLKDVIVRSNPQASLVRSGSSSEV
Protein: Palmitoyltransferase PFA4 (EC 2.3.1.225) (Protein S-acyltransferase) (PAT) (Protein fatty acyltransferase 4) (J9VJ99)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function. Responsible for the modification of a subset of proteins that are critical in cryptococcal pathogenesis, with substrates involved in cell wall synthesis, signal transduction, and membrane trafficking. Palmitoylates chitin synthase CHS3.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03199}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03199}.
Interaction partners:
Sequence:
MAARNWSRVWVGGTVILISFIAFSSQIFVIWPWYGREISLDLLMLLVPLNLAAFMIFWNYRLCVITSPGTVPEGWRPNIGAMDGMEVKKGTHTPRYCKNCAHYKPPRAHHCRQCKTCWLKLDHHCPWIGNCVGFYNQGHFIRFLLWVDIGTTFHLIIMVRRVLYIAEYYHEPTLADVLFLVFNFATCVPVWLCVGMFSIYHVYLACGNSTTIEGWEKDKVATLIRRGKIKEVKYPYNIGIYKNIKSVLGPNPLLWLWPQKMQGDGLSFPVNPSAGDHMTQYFWPPQDPSRLPNPPPIPAHASPFVYGNNGFNPNLRPTNSLRARRSSTPRIDEDEYSHEQGRHYSSGDERDNGSISASSSPEPYLSDYDHYDEGPMYPGERMTTLVPRVRRGSEGWEVAPGGGWNAYAGMMDEEVGWDDEAGYDEAPGEDPYVERPWEMRGRYNVYDPEEESGYTH
Protein: Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27) (O75934)
Organism: Homo sapiens (Human)
Function: Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Subcellular location: Nucleus {ECO:0000269|PubMed:12169396, ECO:0000269|PubMed:20176811, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:29301961, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:30705154}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
Interaction partners:
- Pleiotropic regulator 1
- Pre-mRNA-processing factor 19
- Pre-mRNA-processing factor 17
- 116 kDa U5 small nuclear ribonucleoprotein component
- U5 small nuclear ribonucleoprotein 40 kDa protein
- Pre-mRNA-processing-splicing factor 8
- RNA helicase aquarius
- Pre-mRNA-splicing factor SYF1
- Spliceosome-associated protein CWC15 homolog
- Cell division cycle 5-like protein
Sequence:
MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF
Protein: Uncharacterized protein (Q387I2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAEGEKVVVRALGVCWTAAAMEAAVYELLQHVSAYVVHPGDSVAKFVEAPQSGQCSVALGGLQLLQQLFPYLYDEKKYLCEVIIKNCEVHQASIGVMCRVDFVAYVVLHAFHTLVRGVPLLPRGASLLDSFSSVSWGDDLPWTRNVNPTEVRESHWCRNLLGDFIKKLSVIVHPVDPQDLLAEVASSAGLVEVESSGGCDTPFGFLSSLLLREYLRRTYAYDSFSCGFEVAALAAECFVRVYPHLMLSSRRAGEPGKDVVTSLHGLVDRLLWRVSDDAGNRRVPHGRVGCVISGVAFVTTLHAGGAGRDSTLGTCSLSPFNALGTLLREDRHDGALLLVSRFPTVYEGENNLGIRHLLSVVRGAEEKLLVIAVEGKVCGEVLYYMETLGNCSRTVLVAAAVGRATMTQLALTFRTLPRTLESLKLSPVKCRLKMCALSSSSDGLRRRCGGVEPQSFLLSLAPLYTEASGNDSRVMRNIISVFLGGRCVVESALVECLFQRQLHHLINVLCAPTPHNAMIPAGGTSEGLAVSYLSYLTDNFEDDGSSFGTFKIAVIKAVRDAINSYMECVLRKSGGLTADDAIAHLGASQERFQNVEWGSVDQSVRGCCVTVVPGHQEPHFGPLYRVTIPTPPLFSAFEASWPVSVSVKSNHLLADIREWEGRVEVASAYICIGRCLDTLCLSGVVGKRSNVGEGKNSEGASDFFFFPSVV
Protein: Ethylene-responsive transcription factor ERN2 (ERF transcription factor ERN2) (NF box-binding protein 2) (Protein ERF REQUIRED FOR NODULATION 2) (A9Y0K8)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Transcription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs). Binds to the GCC box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs. Involved in early stages of root nodule development. Functions redundantly with ERN1. Is essential with ERN1 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241}.
Interaction partners:
- Protein NODULATION SIGNALING PATHWAY 1
- Protein NODULATION SIGNALING PATHWAY 2
Sequence:
MEIQFDEPKKSLRPKKVNKFKGRNKKSETRDKFVGVRQRPSGRYVAEIKDTTQNIRMWLGTFETAEEAARAYDEAATLLRGSKTRTNFVTHVSYDSPLASRIRHLLNNRKKGTKQQDMNGISSTTSHADTTNDTTSDGSTSSTTNCIGTASGAINSTSASGVTSTSTNISTSASGVASTSTDISTNSSNTNVNDKSESLLSSSTTMQKPNLFEDAYRPDMSNLTNEYESSSYKSNVSWDFGPIFDNFPFDQWLDMTNNDGLLCDMVDKGVSEFERMKVERQISASLYAINGVQEYMKNVQDCNEAQWNLSPLC
Protein: Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (P57790)
Organism: Rattus norvegicus (Rat)
Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination. KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine residues in KEAP1, leading to inactivate the ubiquitin ligase activity of the BCR(KEAP1) complex, promoting NFE2L2/NRF2 nuclear accumulation and expression of phase II detoxifying enzymes. In response to selective autophagy, KEAP1 is sequestered in inclusion bodies following its interaction with SQSTM1/p62, leading to inactivation of the BCR(KEAP1) complex and activation of NFE2L2/NRF2. The BCR(KEAP1) complex also mediates ubiquitination of SQSTM1/p62, increasing SQSTM1/p62 sequestering activity and degradation (By similarity). The BCR(KEAP1) complex also targets BPTF and PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9Z2X8}. Nucleus {ECO:0000250|UniProtKB:Q9Z2X8}. Note=Mainly cytoplasmic. In response to selective autophagy, relocalizes to inclusion bodies following interaction with SQSTM1/p62. {ECO:0000250|UniProtKB:Q9Z2X8}.
Interaction partners:
- Cullin-3
- E3 ubiquitin-protein ligase RBX1
- Nuclear factor erythroid 2-related factor 2
- Sequestosome-1
- Prothymosin alpha
- Serine/threonine-protein phosphatase PGAM5, mitochondrial
- Partner and localizer of BRCA2
- Dipeptidyl peptidase 3
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Transcription factor p65
Sequence:
MQPEPKPSGAPRSSQFLPLWSKCPEGAGDAVMYASTECKAEVTPSQDGNRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASLSVPRNRSGGGVIDGHIYAVGGSHGCIHHSSVERYEPDRDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHSCIYAAGGYDGQDQLNSVERYDVETETWTFVASMKHRRSALGIAVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRLTSGRSGVGVAVTMEPCRKQIDQQNCTC
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (F1LSY7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
Interaction partners:
Sequence:
MRRCNDIQSFGRASTVTLPEALLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENTPTTVSQDVEEKLPRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQFQKELEKIQLLQQQQLPFHPHGDLTQDPDFLDSSGLFSESSGTSSPSPSPRASNHSLNSSSSASKAGTSPSLEPDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACSLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKRHHYRELPLEVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCRHERLFQTYYWHEPTEAQPPGIPDAL
Protein: threonine--tRNA ligase (EC 6.1.1.3) (Threonyl-tRNA synthetase) (Q8IGC5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGDNVVTELNNLDLNNQKAAKMKKEKKEKPSGGGDTRKELSPLPKYIEERNVFWEKCKAEYEAELAAKKREPIKVTLPDGKQVDATSWETTPYEVARGISQGLADNTVISKVNGEVWDLDRVLEGNCTLQLLKFDDPEAQAVFWHSSAHIMGEAMERIYGGHLCYGPPIENGFYYDMHLEGEGISTNDYGAMEGLVKQIVKEKQNFERLEMKKSDLLEMFKYNEFKVRILNEKVTTDRTTVYKCGSLIDLCRGPHVRHTGKVKALKITKNSSTYWEGKADAETLQRVYGISFPDPKQLKEWEKLQEEAAKRDHRKIGREQELFFFHELSPGSCFFQPRGAHIYNTLMGFIKAEYRKRGFQEVISPNIYNAKLWMTSGHWQHYAENMFSFEAEKEKFALKPMNCPGHCLIFDNRNRSWRELPLRMADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAPEQIKSEMKGCLEFLKYVYTIFGFSFQLVLSTRPDNYLGELEQWNDAEKALAESLNEFGMPWKENPGDGAFYGPKIDITIMDALKRAHQCATIQLDFQLPIRFNLSYIADDGEKKRPVIIHRAILGSVERMIAILTENFAGKWPFWLSPRQVMVVPVGPAYDQYAQSVRDQLHDAGFMSEADCDAGDTMNKKIRNAQLAQFNFILVVGDKERSSNTVNVRTRDNKVHGEVSVAELITKLQKIRDEFIANEDSF
Protein: Syntaxin binding protein 3 (Syntaxin binding protein Munc18-3) (Q99PV2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Syntaxin-4
- Syntaxin-1B
- Vesicle-associated membrane protein 2
- Synaptosomal-associated protein 23
- Vesicle-associated membrane protein 8
- Syntaxin-1A
- Syntaxin-3
- Syntaxin-2
- Vesicle-fusing ATPase
Sequence:
MAPPVTERGLKSVVWRKIKTTVFDDCRKEGEWKIMLLDDFTTRLLSSCCKMTDLLEEGVTVIENIYKNREPVRQMKALYFISPTPKSVDCFLRDFGSKSEKKYKAAYIYFTDFCPDSLFNKIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPSNAGRKEAVMEAMAEQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDENGLIKGKTQSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIEKDTYKYKTDGKEKEAVLEEDDDLWVRVRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQISKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQRVKDSMLVLLPVLLNKNHDNCDKIRAVLLYIFGVNGTTEENLDRLIHNVKIEDDSDMIRNWSHLGVPIVPPSQQAKPPRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSRCPAVWNGSGAVSARQKPRTNYLELDRKNGSRLIIFVIGGITYSEMRCAYEVSQAHKSCEVIIGSTHILTPRKLLDDIKMLNKSKDKVSFLKDE
Protein: Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB) (Q05856)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Involved in germline establishment and development.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P14678}. Nucleus, Cajal body {ECO:0000305}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P14678}.
Interaction partners:
- Small nuclear ribonucleoprotein F
- Probable small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D3
- Probable small nuclear ribonucleoprotein Sm D2
- Probable small nuclear ribonucleoprotein Sm D1
- Probable small nuclear ribonucleoprotein G
- U1 small nuclear ribonucleoprotein A
- U1 small nuclear ribonucleoprotein 70 kDa
- U1 small nuclear ribonucleoprotein C
- U6 snRNA-associated Sm-like protein LSm4
Sequence:
MTIGKNNKMIQHLNYRVRIVLQDSRTFIGTFKAFDKHMNLILGDCEEFRKIRSKNSKVPEREEKRVLGFVLLRGENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMPINLSAVPAGLQGPVRGVGGPAQQHMAPMGRGVPRAPMMGAPPPGMIPGGMPSMPGNMGRGAPPPMRGPPPSMIRGAPPPGRGGY
Protein: Sucrose transport protein SUC1 (AtSUC1) (Sucrose permease 1) (Sucrose-proton symporter 1) (Q39232)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). This transport is both voltage- and energy-dependent. Can also transport other glucosides such as maltose, alpha-phenylglucoside and beta-phenylglucoside. May also transport biotin. Required for normal pollen germination and anthocyanin accumulation induced by sucrose.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sugar transport protein 4
- Cyclin-dependent kinases regulatory subunit 1
- Sugar transport protein 1
- Probable polyol transporter 6
Sequence:
MGAYETEKPTKDAAALETQSPEDFDQPSPLRKIISVASIAAGVQFGWALQLSLLTPYVQLLGIPHKWSSLIWLCGPVSGMIVQPIVGFHSDRCRSKFGRRRPFIATGAALVAVAVFLIGYAADFGYKMGDKLEEKVKVRAIGIFALGFWILDVANNTLQGPCRAFLADLAAGDAKRTRVANAFFSFFMAVGNVLGYAAGSYTNLHKMFPFTMTKACDIYCANLKTCFFLSITLLLIVTVTSLWYVNDKQWSPPPRNADDDEKTSSVPLFGEIFGAFKVMKRPMWMLLIVTALNWIAWFPFLLFDTDWMGREVFGGDSDGNERSKKLYSLGVQSGAMGLMFNSIVLGFMSLGVEWIGRKLGGAKRLWGIVNFILAAGLAMTVLVTKFAEDHRKTAGDLAGPSASVKAGALSLFAVLGIPLAITFSTPFALASIFSSCSGAGQGLSLGVLNLAIVIPQMIVSLGGGPFDALFGGGNLPAFIVAAIAAAISGVLALTVLPSPPPDAPKATTMGGFH
Protein: RNA helicase (EC 3.6.4.13) (Q8SWT2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Dosage compensation regulator mle
- LD20892p
Sequence:
MQRDRDSSGSNARKGNRPPGLRGKDIGLYYRNLARQQKKDRGENAESKEPQIRLGCNVSAPSGVLERVKELMEDYSRAPSRQNVDDKNVDAKFQQQFRHLLSVNFEEFVAETKERNADLDWVNPKLDERLQLELGQRQLEENAKKRLEARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGRVRPGICYNLFSRAREDRMDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFKSPFYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAYRDSRYSHAERDFCYKNFLSSMTLQQLERMKNQFSELLYNYKFLASSNCKDAASNKNSEKIPLLRAIIGAGLYPNMAHLRKSRQIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQRQKSTDLFLLDSTMVFPMALIIFGDGVEAGVTQNTPYLCVAKTYYFKCNRETADVVIQLRSNLEKLLLKKALYPAPIEENGYEKQLIKAIELLLSLDERLGEDYISSDEIDDI
Protein: PHD and RING finger domain-containing protein 1 (CTD-binding SR-like protein rA9) (Q63625)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- DNA
- Nonsense-mediated mRNA decay factor
Sequence:
MDDDNLDELVAHSPGPDGPPQVGSSELASDAEESSNGHSEDSEDDTGSEQDDDTDGEETEGLSEEEDPEDRSGSEDSEDGIEVPTAAVETQRKLEASSTPNSDDDAESCPICLNAFRDQAVGTPETCAHYFCLDCIIEWSRNANSCPVDRTIFKCICIRAQFNGKILKKIPVENTRACEDEEAEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAVPGVDPTHDAAPVSDEEVSLLLADVVPTTSRLRPRVGRTRAIARTRQSERVRATVNRNRISSARRVQHVPRYLMSSLLDETIEAVATGLSTAVYQRPLTPRVPAKRKRKAGRRKKVLGRKKTRSRSSVKSKSGGTRAKKRQHRVRRTKGRKLKNEVTARSRIARTLGLRRPVRGTSMPSVYKPVDPSLGLMRADIGAASLSLFGDPYALDPFDSNGEQSADPPSPLSAKRRVLSRSALQSHQPVARPVAMGLARRQLPAVAPEPSVEEAPVPDLLGSILCGQSLLMMSSADVVIHRDGSLSAKRAAPVSLQRNSVTQSREESRLRDNLQPGALPSESVSGGLIGDRRPNSGLSCGDRTALRCLPAQIVQTPVRSDSSVTPRSGLSGNLSDESRPKWKHSNSPRLNGSNVRVGSASTKTMTHSNFPSKNIAPGHPQKTDPRRPDFSKLPRIPKIRRDGSNSTQDQAPASGQTVELPSACISRLTGREGPGQPGRGRADSEPSSRGPQETGSHTSGSRPPAPSSHGNLAPLGPSRGKGIGSSFESFRINIPGNTAHCSQLSSPGFCNTFRPVDSKVQRKENPSPLFSIKKPKQLKSEIYDPFDPTGSDSSPPSSSPESLGSGLLPSEITRTISINSPKAPAFQTVRCVTSYRVESVFGTEMDPDPQPPGEPVSGMLELLGKGPAEGASDLEQEGLGEIEPTEIQGSSARAQRPSPPDPWDDEDGVSCTPFFGSEERTVTCVTVEEPSVPSPDAPQITTHRIVEFRASSRSRSTSSSRSRKKTKKKKKVAREHQRTRSSTRSGSRDRTSRSVSPFTEEHTKRHRAKTKSRRSSSDRASSQDRAKRRKDRDREHRRGPWGHGRCWRKSRSRSGSPGSSSCERHESRRRKRRHSGSRSRGRDGSPHSSLERDRRHKHRERSRERMDKKESMTRSRERRRWRSRSPSVEHRTRRPHSREKHPHSPEKKGAVREVSPAPAPQGEPRQDGDHSTKPPVSEVSVLPEVVSVLPEVVVADLNPPEVPPVLAESVSCVPEDLDYGDSVEAGHVFEDFSNEAIFIQLDDMSSPPSPESTDSSPERDFLPNPILPPASLPQNSTLPVTQREVLPIHSEDISKPAPQPLAPSDQCLLRQDTVETTATTLSTPGVLPMGKDSPLLSGRGCEVVRPKDAVAPAPLLRSRTLVKRVTWNLQEAEASTPALDRDPRTPLQRPQRPQEGDWDAEDRALIGFQQAPFSELPPPIHVLQESGLPDADPSQPPGVPRAEGPPAVGTLHSAGGILAQVYSPNMPPPLAQPSSIPPYALVNQPSVQLILQGTLPLASCGAAQNLAPVPTMPATASELAVPTTNNSEERTATPKTAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRKHKKTEAGEEPPTQGAET
Protein: Exocyst complex component 6 (Exocyst complex component Sec15) (Q9VDE6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular location: Cell projection, rhabdomere {ECO:0000269|PubMed:16155582}.
Interaction partners:
- Exocyst complex component 8
- Exocyst complex component 5
- Exocyst complex component 3
- Exocyst complex component 4
- Exocyst complex component 7
- Exocyst complex component 2
- Exocyst complex component 1
- Rab11
- LD44762p
- Dilute class unconventional myosin, isoform C
Sequence:
MSKVTVQDIEAVDDYWGPTFRSILEGNNTKQIGDQLEQRIRSHDKEIERICNLYYQGFIDSIQELLQVRTQAQQLHNEVHSLDTSLRQISASLIQQGNDLVRARQIESNLASAIEALKSCLPALECYMKFTQQAKNKQYYQALRTLETLETEHLTRLKTHNYRFATQMQIQIPIIKENIRRSSASDFREFLENIRKFSPRIGELAITHTKQLQKRDINAIIAEHMQQMNGGEAGGAGAGGDDDGANVSAQDLIDFSPIYRCLHIYMVLGQREYFEKDYRQQRRDQAKLVLQPPPNMHDNLEAYKTYICAIVGFFVVEDHVKNTAGDVVTSSYLEDLWSSSLTKFVNEISMSSSSCTDPNILLRIKNLIMLSINTFKCYGYTVNILWELLHNMRDHYNEVLLQRWVHVFREILDKEQFLPMVVQNTEEYECIIERFPFHSEQLENAPFPKKFPFSRMVPEVYHQAKEFMYACMKFAEELTLSPNEVAAMVRKAANLLLTRSFSGCLSVVFRQPSITLTQLIQIIIDTQYLEKAGPFLDEFVCHMTNTERSVSQTPSAMFHVARQDAEKQVGLRICSKIDEFFELSAYDWLLVEPPGIASAFITDMISYLKSTFDSFAFKLPHIAQAACRRTFEHIAEKIYSIMYDEDVKQISTGALTQINLDLMQCEFFAASEPVPGLKEGELSKYFLRNRQLLDLLILEEWSTYFHDYGKQENRYHLVQPQSIIVILEKIREADKKPIFSLVRKNDKKKLLETVLKQLKHIADRQN
Protein: Palmitoyltransferase ZDHHC18 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 18) (DHHC-18) (Zinc finger DHHC domain-containing protein 18) (Q5Y5T2)
Organism: Mus musculus (Mouse)
Function: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK. Palmitoylates HRAS and LCK. Acts as a negative regulator of the cGAS-STING pathway be mediating palmitoylation and inactivation of CGAS. May also have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9NUE0}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MKDCEYQQISPGAAPPPASPGARRPGPAAPPAPSPGPAPGAPRWSGSGSGSGSLGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILSTTILFFVFDCPYLARTLTLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATICEAAALEKQIDNTGSSTYRPPPRTREVMINGQTVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLLSQGSNFLSALKKTPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSSKRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQSDTALPSPIRSDDPACGAKPDASMVGGHP
Protein: At5g26910 (GPI-anchored adhesin-like protein) (Q6NQ74)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Pre-mRNA-splicing factor 38
- Protein STABILIZED1
- Pre-mRNA-processing protein 40C
- tRNA
- Microfibril-associated protein-like
- Microfibrillar-associated protein-like protein
- Sm-like protein LSM2
- Sm-like protein LSM8
- At3g63430
- Sm-like protein LSM4
Sequence:
MEVVERKRSRGGFLNLFDWHGKSRKKLFSGSTSELSEESKQPAQNLLKSRVSLIEVDEIGKSSSNNQRSDSSCCASSVTSDDGQGTRAPSVVARLMGLESLPVPNVQEPRLNPDLDPFLLRPSQNTNRWDAYENLGYVNLRSDYDGISWDHLDSRTNNGRNQPIERFQSETFPPRSAKPICVTNNRHLSPIRSPGFVPSRNPIYVMEAASRMIEPSPRMVARTRFSPSNSPSSVPMRIQDLREKLEAAQKVSSRQNSNDTFNLKYPSGKHNEKRITTSLTTPSTSKFMGKSSTDGLKGKVKPSYVSAQAKAGTTPLSVTRNSANQKEKADAKKCVVKSQNALRGAPISMGKNMFKQNNQKQNCRDNQPSMTSVLNQKSSKVNNKVVNKVPVESGSISKQLGLSTASAEKNTSLSLSRKKTLPRSKKLPNGMQKSGISDDKRTKRSENMIKCNITIDGGLNKGKDDRKKEMDVISFTFSSPIKGLSSDSLSSTQGIGQDTDSAVSFNIGGDSLNALLEQKLRELTSKLESSSCSLTQEEPSYSIPMDEMNGMISFSSEYEKSTQNGLRKVLSESESVSDCTSFYDKQKFQIQAEEHEVSSISTVTEADDLRSSCSKGFSDCRQTAEYGTIQSSSDQELTWVSLNESHQAQDESELSESVVTLSYSEAEERLDWEFEYISEILGSDQLMVKEYALGMATDVLPASLFDEMEGRGEVTAAKIKRKTLFDFVNKCLALRCEQMFMGSCRGLLGKGGFLFEQRDWLAEELNREIHGLKKMREMMMDELVDKEMSSFEGRWLDFERETYEEGIDIEGEIVSTLVDDLVNDLVSGTQRRTLRQREGVVSALVEPHLLSAF
Protein: Inactive serine/threonine-protein kinase BKN2 (Protein SUPPRESSOR OF ZED1-D2) (Pseudokinase BRASSIKIN 2) (Receptor-like cytoplasmic kinase SZE2) (Q9LFL6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:30947022, ECO:0000269|PubMed:31829135}; Lipid-anchor {ECO:0000269|PubMed:30947022, ECO:0000269|PubMed:31829135}; Cytoplasmic side {ECO:0000269|PubMed:30947022}.
Interaction partners:
- RNA-binding
- Cysteine-rich repeat secretory protein 55
- Probable serine/threonine-protein kinase WNK4
- Mitogen-activated protein kinase kinase kinase 14
- Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 6
- Probable apyrase 5
Sequence:
MGNCLKPLKEQPPSASPKPLTIPSSSVEPVKENLKEFRFAELNKATKRFRKYMVIKGNDNGFTRTFYEGCINETTFAPSRTGITVSVMECYQDNSQTLQDWKEEVKSLGRISHPNLVKLLGYCCEENKSFLVFEYLHKGSLNRYIFGKEEEALPWETRVKIAIGAAQSIAFLHWVKNSALYRELRMYNILLDEHYNTKLFYLGSKKLCLLEESVTTAFIGRTVYIPPEYVISGHLGTKSDVYTFGVILLEILTGLKASDGKKNENMQSLHVWTKPFLSDQSKIREIIDPRLGNDYPVNAATQMGKLIKRCIKLDTRKRPSMQQVFDGLNDIAEIKD
Protein: Probable aldo-keto reductase 4 (EC 1.1.1.-) (Q93ZN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Expressed protein
- Large ribosomal subunit protein eL36y
- At1g17080/F6I1.24
- Large ribosomal subunit protein eL29y
- Aldo/keto reductase family protein
- Small ribosomal subunit protein eS25x
- At2g27680/F15K20.22
- Small ribosomal subunit protein uS10y
- Large ribosomal subunit protein eL8y
- Large ribosomal subunit protein uL1x
Sequence:
MAEACGVRRMKLGSQGLEVSAQGLGCMGLSAFYGAPKPENEAIALIHHAIHSGVTLLDTSDIYGPETNEVLLGKALKDGVREKVELATKFGISYAEGKREVRGDPEYVRAACEASLKRLDIACIDLYYQHRVDTRVPIEITMGELKKLVEEGKIKYIGLSEASASTIRRAHAVHPITAVQIEWSLWTRDVEEEIIPTCRELGIGIVAYSPLGRGFFASGPKLVENLEKDDFRKALPRFQEENLDHNKIVYEKVCAISEKKGCTPGQLALAWVHHQGDDVCPIPGTTKIENLKQNIGALSVKLTPEEMTELEAIAQPGFVKGDRYSNMIPTFKNAETPPLSAWKAA