wanglab/gogpt-training-data huggingface dataset:
Protein: BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15) (Q96SI1)
Organism: Homo sapiens (Human)
Function: During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain.
Subcellular location: Nucleus {ECO:0000269|PubMed:38113115}.
Interaction partners:
- Transmembrane protein 18
- Glucosamine-6-phosphate deaminase 2
- Neuronal growth regulator 1
- Mitochondrial carrier homolog 2
- SH2B adapter protein 1
- Melanocortin receptor 4
- Alpha-ketoglutarate-dependent dioxygenase FTO-)-demethylase FTO)
- Transcription factor AP-2-alpha
- SUMO-conjugating enzyme UBC9
- Transcription factor AP-2-beta
Sequence:
MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD
Protein: Ubiquinol-cytochrome c reductase complex assembly factor 5 (Small integral membrane protein 4) (Q8WVI0)
Organism: Homo sapiens (Human)
Function: Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation (By similarity). Mediates early complex III biogenesis (By similarity). Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (By similarity). Also involved in the first steps of cytochrome c oxidase complex (complex IV) assembly.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:34969438}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MFTRAQVRRILQRVPGKQRFGIYRFLPFFFVLGGTMEWIMIKVRVGQETFYDVYRRKASERQYQRRLEDE
Protein: Uncharacterized protein, isoform C (Uncharacterized protein, isoform K) (A0A0B4KFB8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Probable ATP-dependent RNA helicase DDX46
- Microfibrillar-associated protein 1
- Splicing factor 3B subunit 4
- Splicing factor 3B subunit 1
- Pre-mRNA-splicing factor 38
- Splicing factor 3A subunit 1
- Pre-mRNA-splicing factor RBM22
- Probable U2 small nuclear ribonucleoprotein A'
- Puff-specific protein Bx42
- Cell division cycle 5, isoform A
Sequence:
MDASLEESMDSDGASSPITKTEATESPPEAGLNGNGSGSGSTSQETPNYGVAILKEKPSEAHRSKPFNAFSGRPIGEHTAQQQALQQQQLQQQQQPQQPQQQAPSGANGVTGPPEIWVETKAEDGRSYYYHAVTRETTWSRPDGPAVKIMTQAEVEEMAKRPAQAAKTEAKAGETSVEIPPVSSHLTSQPPPHLMSQPPPNAAAPLLSQPPPNVRQQPPPMFQPPGMQAPPGFGQPPFCMPPPTYGFPGGPAPAGAPWGVGIPPWQQQQHMQDKPAKSLIIKPGVIDPAVIARAAEWSEHRAPDGRPYYFHAGRGESVWEKPQALRDMEAARMAAHSGVAPAVATAPSGLPPHLLPNPMMHMPPGSGPPGFDPHAAFAAAAAAMKANSENTKAAQAAALEKEAKKAAEEKRKKEEEQKKAAASAKQTDKSRPVTSTPIAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPEDLLNREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRVRMISKSKRAEDAALEAEQRAAKERALVPLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDFRSLMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKEDKLLKKEQIRKDFLDMLRERHDIERHTRWYDIKKKFESDPRYRMVDSMYREEYFEDYLHIMKEEKRKEREMREQRERERHRELKSDRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKSEKSKKRDTTPEEGEHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQRTLAGHLRDRDKEREHHMREECIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDRERKFNEHIDNLMKKKRERFREMLDEISTLQLTSTWKEIKKLIKEDPRYLKYNSDKGEREFRDYIKDKTMTAKTSLRELLQECKFITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHMEEERNTIVLGFLEELNKRGPPPPPTASESTRRNK
Protein: Deubiquitinase DESI2 (EC 3.4.19.12) (Desumoylating isopeptidase 2) (DeSI-2) (PPPDE peptidase domain-containing protein 1) (Palmitoyl protein thioesterase DESI2) (EC 3.1.2.22) (Protein FAM152A) (S-depalmitoylase DESI2) (Q6DC39)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9D291}.
Interaction partners:
- Ubiquilin 4.
Sequence:
MANEPVILNVYDMYWINEFTSSLGIGVFHSGIEIYGREFAYGGHPYPFSGIFEITPGDATELGETFKFKEAIVLGSTDFTEEDVERIVEEMGKEYKGNAYHLMHKNCNHFSSALSEILCGREIPRWVNRLAYFSSCVPFLQSCLPKEWLTPAALQSSVSQELQGELEEAEDAAASASTPTCAVAPAPRPARHQPRR
Protein: Homeobox protein Hox-C5 (Homeobox protein Hox-3.4) (Homeobox protein Hox-6.2) (P32043)
Organism: Mus musculus (Mouse)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-C6
- Homeobox protein Hox-C4
- Homeobox protein Hox-B6
Sequence:
MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHALGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL
Protein: Small ribosomal subunit protein eS30B (40S ribosomal protein S30-B) (P0CT63)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein eS28A
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL5B
- Small ribosomal subunit protein uS9B
- Elongation factor 3
- mRNA export factor elf1
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS2A
- Small ribosomal subunit protein uS4A
Sequence:
MGKVHGSLARAGKVKSQTPKVEKQEKPKQPKGRAYKRLLYVRRFVNVTNMVGGKRRMNPSS
Protein: Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T) (Q9NPD8)
Organism: Homo sapiens (Human)
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.
Subcellular location: Nucleus {ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19887602}. Note=Accumulates to chromatin.
Interaction partners:
- Fanconi anemia group D2 protein
- E3 ubiquitin-protein ligase FANCL
- Fanconi anemia group A protein
- Fanconi anemia group I protein
- Fanconi anemia group B protein
- Fanconi anemia group G protein
- Fanconi anemia core complex-associated protein 100
- Fanconi anemia group C protein
- Fanconi anemia group E protein
- Fanconi anemia group F protein
Sequence:
MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQKRKASQLVGIEKKFHPDV
Protein: DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31) (P19387)
Organism: Homo sapiens (Human)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:9852112}.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- Transcription elongation factor SPT5
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB11-a
Sequence:
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
Protein: HEAT repeat-containing protein 5A (Q86XA9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MELAHSLLLNEEAYNQLGEVQKAEFIFEWLRYLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLAILYSIGDTFSVHEAIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAKNEAIFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGIILAKAVISKHPGTAASRQSIRRVSLEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQIDAVCCRRCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILSVILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMTLAEDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEEVTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAASTFLLPPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGSCSSDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSSGATIKSPEDVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKATKPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKSRTAWTDLLRSALTTILDCWDPVDETHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYSLASCIMEKLQEIDKRKPENTAELEIFQEGIKVLETLVTVAEEHHRAQLVACLLPILISFLLDENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGNQESVKVKIPTSKYTKSPGKNSSIQLKTSFL
Protein: RNA polymerase II-associated protein 1 (Protein PAF1) (P38351)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II. Also has a role in transcription-coupled histone modification. Required for activation of the RAD6/UBC2-BRE1 ubiquitin ligase complex, which ubiquitinates histone H2B to form H2BK123ub1. Also required for the methylation of histone H3 by the COMPASS complex to form H3K4me, by SET2 to form H3K36me, and by DOT1 to form H3K79me. RNA polymerase II associated protein important for transcription of a subset of genes. Required for both positive and negative regulation. Negatively regulates MAK16 expression. Also required for efficient CLN2 transcription in late G1 and may be involved in transcription of galactose-inducible genes.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:15643076}.
Interaction partners:
- RNA polymerase-associated protein RTF1
- FACT complex subunit POB3
- RNA polymerase-associated protein LEO1
- RNA polymerase-associated protein CTR9
- Cell division control protein 73
- FACT complex subunit SPT16
- CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4
- Transcription elongation factor SPT5
- DNA-directed RNA polymerase II subunit RPB1
- Transcription elongation factor SPT4
Sequence:
MSKKQEYIAPIKYQNSLPVPQLPPKLLVYPESPETNADSSQLINSLYIKTNVTNLIQQDEDLGMPVDLMKFPGLLNKLDSKLLYGFDNVKLDKDDRILLRDPRIDRLTKTDISKVTFLRRTEYVSNTIAAHDNTSLKRKRRLDDGDSDDENLDVNHIISRVEGTFNKTDKWQHPVKKGVKMVKKWDLLPDTASMDQVYFILKFMGSASLDTKEKKSLNTGIFRPVELEEDEWISMYATDHKDSAILENELEKGMDEMDDDSHEGKIYKFKRIRDYDMKQVAEKPMTELAIRLNDKDGIAYYKPLRSKIELRRRRVNDIIKPLVKEHDIDQLNVTLRNPSTKEANIRDKLRMKFDPINFATVDEEDDEDEEQPEDVKKESEGDSKTEGSEQEGENEKDEEIKQEKENEQDEENKQDENRAADTPETSDAVHTEQKPEEEKETLQEE
Protein: SNF1-related protein kinase catalytic subunit alpha KIN11 (AKIN11) (EC 2.7.11.1) (AKIN alpha-1) (AKINalpha1) (SNF1-related kinase 1.2) (SnRK1.2) (P92958)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalytic subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, a central regulator of cellular energy homeostasis, which, in response to seemingly unrelated darkness, sugar and stress conditions, activates energy-producing pathways and inhibits energy-consuming processes. May play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants. The SnRK complex may also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase and in assimilation of nitrogen by phosphorylating nitrate reductase. In vitro, KIN11 exhibits kinase activity on sucrose phosphate synthase and the kinase activity is inhibited by PRL1. May be a subunit of a SCF ubiquitin ligase complex and thus be involved in proteasomal ubiquitination. Involved in innate antiviral defenses. Phosphorylates REM4.1 in vitro. Phosphorylates ADK2 in vitro.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:19211700, ECO:0000269|PubMed:25071807}. Cytoplasm {ECO:0000269|PubMed:19211700, ECO:0000269|PubMed:24498147, ECO:0000269|PubMed:25071807}. Endoplasmic reticulum {ECO:0000269|PubMed:29406622}. Note=Co-localized with ER marker when associated with FLZ6 or FLZ10. {ECO:0000269|PubMed:29406622}.
Interaction partners:
- Sucrose nonfermenting 4-like protein
- SNF1-related protein kinase regulatory subunit beta-2
- SNF1-related protein kinase regulatory subunit beta-1
- SNF1-related protein kinase catalytic subunit alpha KIN10
- SNF1-related protein kinase regulatory subunit beta-3
- Phosphoglucan phosphatase DSP4, chloroplastic
- Regulatory-associated protein of TOR 1
- Asparagine synthetase 1
- Serine/threonine-protein kinase TOR
- Basic leucine zipper 63
Sequence:
MDHSSNRFGNNGVESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKRITIPEIRQHRWFQTHLPRYLAVSPPDTVEQAKKINEEIVQEVVNMGFDRNQVLESLRNRTQNDATVTYYLLLDNRFRVPSGYLESEFQETTDSGSNPMRTPEAGASPVGHWIPAHVDHYGLGARSQVPVDRKWALGLQSHAHPREIMNEVLKALQELNVCWKKIGHYNMKCRWVPGLADGQNTMVNNQLHFRDESSIIEDDCAMTSPTVIKFELQLYKAREEKYLLDIQRVNGPQFLFLDLCAAFLTELRVI
Protein: Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (A0A384NL00)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
Protein: Uncharacterized protein (Q384E8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDVLFPSCVGIAVQHAPHAGHFFSFTFALPLIVIDPFPSAGSHCMIKRRQHTDVCYYSHDRTGMNRLHPLQLLLAYEETRCPYDLPGEKERRRLVGYPSWTEAALTAWSRQSVKYSVAGEVEKRCEGSKSPVLLMDGGTGQPEPVAKGAVNTPTSGEAEKAIRITEAPLLVRLVAREVVAASRLIDDSATSEDAMGSQVDGVFTSHCKPVRSTESHALENRSANPARELLRVKQPATRDIGVGSDICDPGKGPAEERESSGQTRQSAVEDIMVAQGNQVGDLLSNTVERLYAKLQGTALKVVAIDDLNRQLTEKFESLKPRDHVEDKTELSIYLYSLRRQVENLKREWDVHKTALEASEQRLRGNKTDPSERTVRVQIVKDYETPPVPYKKGPFRPLVIPAVGKEGEKKSSASYSDNSEWTSESSSSVPASSRSVVSSSSYTSTSSQPTPTSSSTDHSSSFSTLNSSPSRRTSSVSFSSEEIDSGSTLS
Protein: T. brucei spp.-specific protein (Q38CA5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGAACTKCSREGDVAEDKQVKKEKPAETVTAPDREDNGSAGRSSSGPRVPAIVNDGNCSDGVDCEKFTSCSGKEAAPERADDLSLTSVPLSIRRSSETLPAQPSEKSEPRGNDSSSAVGEAVEASLSAESVRSSMSGGMLSPAREISQISMVVDDGATEISAEVSGECNTLNSVGGTETCDIGALHWPQGRFSLSVSAPCSMVHSSSPPPQRSKCCSRTSRRELQPGSESSLSIATPVHVEVTQTRRIDPCSLTGTSAAGEISAGDATTNHDCKYGPQHCPSGGKPVSGDGTDGLDTAACMKDEARGVEHDPPMQQHRQLQQESGQQRDRREYVDSAETFTPHLSMMDPGAGDTAVDTVDFINCSTLSASVGAVASCVMDETVSAAFLSHVMEQQRQKERRRLSPPVPLHDSVDPRVPRLSTPLTDKPDQGKTVHVEVSDLTPEDESDASAYSVVTDDKPRIRVSDPSVLHRQPLQRDYLTAEDTNGGDMSNKTLRDSPDGADAVNVARQWPMPESTASSNPQGRTTNDLLNMLRDMVQKQDERRQQQQRKYKAFTRIKNPIPLTSPKMREDNELRVDEKEAQSGSASPWSQIWQNRTPLTDGTPNTSLLPRRLSYSPPRDSKYPATKHWIDGEELVHCTDDSRFVTRVS
Protein: Alcohol dehydrogenase 2 (EC 1.1.1.1) (O94038)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Pyruvate decarboxylase
- Pdc12p
- catechol O-methyltransferase
- Aldehyde dehydrogenase
- S-
- Aldehyde dehydrogenase
- Fructose-bisphosphate aldolase
- Phosphoglycerate kinase
- Phosphoglycerate mutase
Sequence:
MSVPTTQKAVIFETNGGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWKGDWPLATKLPLVGGHEGAGVVVALGENVKGWKVGDYAGVKWLNGSCLNCEYCQSGAEPNCAEADLSGYTHDGSFQQYATADAVQAARIPAGTDLANVAPILCAGVTVYKALKTAELEAGQWVAISGAAGGLGSLAVQYAKAMGYRVLAIDGGEDKGEFVKSLGAETFIDFTKEKDVVEAVKKATNGGPHGVINVSVSERAIGQSTEYVRTLGKVVLVGLPAGAKISTPVFDAVIKTIQIKGSYVGNRKDTAEAVDFFTRGLIKCPIKIVGLSELPEVYKLMEEGKILGRYVLDNDK
Protein: Pyruvate kinase (EC 2.7.1.40) (Q9LU95)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- L-lactate dehydrogenase
- Cytosolic enolase 3
- Bifunctional enolase 2/transcriptional activator
- Enolase 1, chloroplastic
- D-lactate dehydrogenase [cytochrome], mitochondrial
- NADP-dependent glyceraldehyde-3-phosphate dehydrogenase])
- Inosine triphosphate pyrophosphatase
- Malate dehydrogenase 3, cytoplasmic
- Malate dehydrogenase 1, cytoplasmic
- Malate dehydrogenase 2, mitochondrial
Sequence:
MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE
Protein: Aquaporin TIP4-3 (Tonoplast intrinsic protein 4-3) (ZmTIP4-3) (ZmTIP4;3) (Q9ATL4)
Organism: Zea mays (Maize)
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Tonoplast.
Interaction partners:
Sequence:
MGKLTLGHRGEASEPDFFRGVLGELVLTFLFVFIGVGAAMTDGATTKGSTAGGDLTAVALGQALVVAVIATAGFHISGGHVNPAVTLSLAVGGHVTLFRSSLYIAAQMLASSAACFLLRWLTGGLATPVHALAEGVGPLQGVVAEAVFTFSLLFVIYATILDPRKLLPGAGPLLTGLLVGANSVAGAALSGASMNPARSFGPAVASGVWTHHWVYWVGPLAGGPLAVLVYECCFMAAAPTHDLLPQQDP
Protein: Glutamate synthase alpha subunit C-terminal domain-containing protein (Q72B18)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Glutamate synthase, amidotransferase subunit, putative
- glutamate synthase
- Pyridine nucleotide-disulfide oxidoreductase
- Pyridine nucleotide-disulfide oxidoreductase
- Glutamate synthase, small subunit
- Cysteine-rich domain/iron-sulfur cluster-binding domain protein
- Pyridine nucleotide-disulfide oxidoreductase
- Heterodisulfide reductase, iron-sulfur-binding subunit, putative
- Ammonium transporter
Sequence:
MADRIIIDADGMPYRELNVRIREAVAAGTQVIDLHGVRGQRFIGNAVEGDVSINILGVPGQDLGAFMRGPHIRVQGNAQDGVGNTMDGGHIVIDGMAGDVLGYAMRDGSILVRGDVGYRVGIHMKSYLDRVPVIVVGGKAGDFLGEYMAGGVIVLLGMDTGKPEAPVAGRSLGTGMHGGVIYIRGEVPEHLLGPGLALSPLDEEDGAALARHVQAYADAFGKDAAEILGASFVKVHPRSHRPYGNMYVGTN
Protein: Rho/rac guanine nucleotide exchange factor (GEF) 18b (F1QCK8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MTVPHKGPSAQPASSSNPSASQNSSSSGSITGEMDEIDAFRVRRPADDTVSLASTVPESLIVEDAHYATVRSELEALAQDFEVESWSLAVDQHFSKTHSKEAIKRQDVIYELIQTEIHHVRTLKIMLRVYARELREALQLDERRLDCLFPRLDSLLELHNHFLSRLRERRVESLQPGSERNYAINKLSDILISQFSGELGDRMKESYGDFCSRHTEAVNHYKEQLQSNKKFQNLMRKLSNLSIVRRLGVPECILLVTQRITKYPVLLERILHNTEAGTEEHEGLAQALGLIKDVIVQVDAQVSLYEKEARLREIASKMEPKSLGKIKDGRVFRKEDLSQGRRKLLFEGTVNWKAASGRLKDILALLLTDVLVLLQEKDQRYVFSTVDNKPSVISLQKLIVREVAHEERAMFLICASSNEPEMYEIHTASKEDRNTWITHIRQAVESCPHTEERLFSEEEEARVARVREYQERLALKDAQITQSLAEKLQLFAELSECVAGLEDSGSRSRLLLRGDTSDLQQGETLLKAAITEVENLQNLLTSRVRGTSAQTEGNQSPSLSLLPRRADTFGGYDSNSSALPKNGSIKKKGPGAGGRTRDRSQRASSDPQLKEVFTCQDHDELDEASSPASTNMWSSCKLPESELYERVLLLSQRLYSLQAIISQQDSHIELQRASILTAERERPGSRTRGTDVLLEQEKQRNLEKHREELANFQRLQSQHRQEQARWEREREKQRRLAEADQQRLKEREEECRRLETRLAEERLELERQRQTYQQDLERLRESTRAVEKEKERLEQQRKLKKHNTVPNTAALYTQELTQLSTSSSFNGEFLLGGAGEQTHPQKSLLRASLSASPADYPERPEVHSRRESSCNTLPAKTEVPIHLISTTNQLHKQGSVQQQIPTKLAALSKGKEKSGKGKSSHRTDSLASVDMKQMLPIKLSARDSDGGHKTRRPISPHQPQHSHSDSLSPPDAYSDAQSSLAPALPKTHNQTSQQTLPYTVSDEAAKEDVIFF
Protein: Musashi RNA-binding protein 2b (Musashi homolog 2b (Drosophila)) (RNA-binding protein Musashi homolog 2b) (Q7SXT6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Neurogranin A
- Zinc finger CCCH domain-containing protein 14
Sequence:
MEGDGSQATSGSPNDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLSYPNIVATYGRGYTGFAPSYSYQFPGFPATAYGPVAAAAAVAAARGSGRGARGRGGYAAYPQSTGPGFPDYGFYSSPSDQRGPPFSFADYGSLGPQAAQLLQSEHATSACNSPLQHLASPDQYKSPGTNPPRPGAFPGASSPGPVADLYGPTSQDSGVGNYISAASPQPGSGFGHSIAGPLIATAFTNGYH
Protein: Uncharacterized protein (Q387Q7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFSRRVASCCPIPTAMYGALHINTKRQASRLVSPLVPVAPSLKHVAGASVTVTGVVLGELSTVSLASNVSLLSLVGPLSQLFMNGFASNPVFMRVISDTMHTYSVLLHSVRGGAAPSPPGRTSEM