wanglab/gogpt-training-data huggingface dataset:
Protein: RNA-binding protein, putative (Q57XH6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Spliceosome-associated protein, putative
- PSP1 C-terminal domain-containing protein
- Retrotransposon hot spot
Sequence:
MSTGDPTVPLEEEAISAEKCTRFFIGGLHRQITPQDVEEYFSNFGDVMTFILKRDPSGNSRGFGWVVFNSPPTGVQRPEPHYLKGVKLTVEPALANVRTDRVRRVPGGGSSIPGRRRERSLSDSSSVSSRNSSLSTGDPRDGVRRPRLYDRHVEGSRLPAFGAVASRLPPLPSEAFVQPPQIQATTFELAAPAPSRDAPAASASETYLCIPLSLCPPEFSNDPRTFCAKLDQSRVGGLSIIPSPSIAQVGPAPHSVPIPQGLPGGTVMVPQHSRSQPVRSGGGGGGRHPKSSGSHHSIPPPLPQPAPPNYDSVMRHNS
Protein: Regulated endocrine-specific protein 18 (P47940)
Organism: Rattus norvegicus (Rat)
Function: May play an important regulatory role in corticotrophs.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:17951542}. Golgi apparatus {ECO:0000269|PubMed:17951542}. Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000269|PubMed:17951542}. Note=Found in the lumen of secretory vesicles (dense core vesicles, DCV) (PubMed:17951542). However, seems to be retained intracellularly and not secreted (By similarity). {ECO:0000250|UniProtKB:P47939, ECO:0000269|PubMed:17951542}.
Interaction partners:
Sequence:
MQSSLKPAGSGVLQLLVCFLLLYSRPSSCSDINAHDGQGQVGSEQLWTFQGLVASVFQYLQLLFHHIVPQGMFWTDDIAYELMTKKVEHLSRLHPQYPCRKEGKVVSPIATTGVRGKQEEKLRLLSPQKSPAVKVNRDRCFTTKVIPKATKQEVTHPSKGFFGPFPTVGLNLVAD
Protein: Double zinc ribbon and ankyrin repeat-containing protein 1 (Q1LXR6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9NVP4}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9NVP4}.
Interaction partners:
Sequence:
MTAGSVAAPQIIPIRIPPPGKAKHEIDSSTPVEIKSESPDVRVLYTLDGSKPELTKRPGFADSTLKYTEPVRLPVGKVYVKAMAISIDGRQSAVVTKVFVVEPSASDERELNAHDEDDSVKNDTAIDGKDVVENGTGVSSVKYLDISSNEAHRALKGPRFLSQRLGPGSSARLTAQNSQNQSADVVESPLKNLTNTQISRIQRETDFLRCPKCLSHRPSDPFARFCLHCGAPVPPIPGQRLPPTEGGQMGLCMHCKTMVPLNTAICVVCESPLDQQLQPQATLRLQDKFICHSCGTGNPAHITHCVTCESQLLRQARPVLSGQRAAPVPSSQGKMVSCSKCNRVNHSDARFCDWCGAKPGHKASSVKCSQCGASSHPYANHCGGCGVFLDGPPRMPLQVNQRQDAEEMQQTASAAELATAPPSVGLRMCADAQTQTVGLFFPSNTELKKRSQQREAELSRQEQMRDRKPLLTAISPGRGFWRKQLDHICAHLRSYTQNNTEFRALIGEPRLGRMISAVIQEDSYEVSLRINFISAPPEESRSSSAGQRSRSVTSESQNLSSVTEGRNSASPENNINTTGSEVKKKKKKKIGTSDVTENQPESKDSLLLKEVGPEGRGRIPAVQQLLDEGADPACLGKDGRPALVAAVLNGHHDVIPVLVQREADVNQASGPLKNTALHEAAALGDEGLKSVEILLGCNASIRKQNDRGQTPYDIAVAAGSSSVLSLMAAHLGQGLLLRHTKARSLSGLDTFS
Protein: Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase TbPK4 (Q26798)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MISVLSPSDFEKAKEFRAFLRNLGLSKSLDLFSEQWDELVKQQKEITTNEERMSEQDKEKSQRVSSAGSTPSVTAARVLRVKHRVVSAVGIEDDLWQPVGHEFLSPAFTTGAGISLEAYEMARQNDAVTLVCTNPYFKEPPPSNLPLEHFDLRVWYESGKTGFEEEKELPISVDSIVAGRYQMLQYLDSAAFSRTVRCMDLHEDREVCLKIIRNSKDFFDQSIDEIKLLKLINSSGDTEENCVVKMYDFFYYKEHMCIVTELLRDNLYRFSKYNRDEETELYFTLPRLQATARQVLTGLRFLHSLGLIHSDLKPENILIQSYSRCAVKIIDFGSSCFLTDNLSSYVQSRCYRAPEVILGCKYDSGIDIWSLGAILAELATGNVLFENNSIPQMLASICSVCNELPSKLLHEGRNTHHYVTKFGAFYEYCENMDLIFHYPVQGTPLPELFGYDDPLYVDFVRSCLTLDHRQRPTAEELLKHPFIHNDYGSAYSKPPPLKKQVADTNGIKDTSI
Protein: Mismatch repair protein, putative (Q38CB3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Mismatch repair protein MSH5, putative
- Proliferating cell nuclear antigen
- Mismatch repair protein PMS1, putative
- Mismatch repair protein MLH1
- MutL C-terminal dimerisation domain-containing protein
- Exonuclease, putative
Sequence:
MRNNFPIPLQYKLGVRYSVPITSMTDDSRQMFSANGAYPTNEDVSALSMPLEDPHSRGNFFTDASAPAAANLFNVLTPTAQQTQRLRGVGRGSSAQTFTRTAAGTLTLSTARRTGTSQGCGDCIMALIDNRAGEVGAAICQLPSLTIIITQYGDSVTYAKTLSFIFSRGPAELLVPETVVGSNFVQTLLRHFNDTTITGVQRRSFDEAQGAHRLLELMSTDEAALEVSNTDRYLCLAAANALVEFLEMTYNYTLLPHTVRVKYLALENYMEVSRLSARALNIIATGTDHLARFPNQKLDKETTEESVKTGNRKPPVRKTLFRSSRELKKDALFVPLATAVNYTITAVGRRLLRSTVLQPLRDPTSIELRYDAVEWLCRDNEALAAIRRSLRLLTGDDLERVISNFSHTPKLATLKTMQRCIDAVVTLWQFLRATTQLLYTLRGLLSKGGTGNAPESEECDDVGDHSNLSSDGVDCSYESQVELHEREGVMEKENFHWPVPPRSSLCSTSEGHRKPPMLLRKLLQTLTTCHMEEICAEIAHYLDESVVHVTGGDGASVGRRPRRTGGAVLQVQQCFAVKSNINGTLDAARHQYSQTIESMFAHAESLKQQYGVGSLRVVYDGVRGYHLCYDSRHERNAPDSIFLQKYSGGKHYALYHSGRAMMDVDVGGDLHGDSQQQRPPFYGSSVLHVETPEPLNTAAQRAAVTKHQVRGRRVTCTTKEMLLLRRGADDVVAEILHTQNGVVHRLIEYLRQRLGKLQAVCDGVAMLDLLIAFATYSRLNACVRPTVLRQGTSFNSSGTYFIEARHPGGLFTANTVQWSDRTNVLLLTGPNASGKTTLLRQVGQLIALAQSGCFVPAREAAIQPCDRIIAHMLCDDLEDAATSSFAREMRELSYLCMNATRESVVLVDELGRRTAAREGMAIAWATVEFLVEKRCRTIFATHYSRLTRLEEGTAGAVKNVHFVVAVEDGAGGSIPVGDDGMVVLVGGTAPLTNVESGSKPASKKSCTLRFEYRLQPGPSHVDCYGLRLASRVGFYAPALKLAWELLPLIGGREGGRSHEGAGDEAVAATIDESEIKSFHSAGSPCCVRVADKVVADVAKSPPVVSPSTCNKEELSMIGGNRISGNHSEDISVASNSRCLRHTCLEGGAVDLSKMLQLSPCGSSTE
Protein: Iron-uptake system permease protein FeuB (P40410)
Organism: Bacillus subtilis (strain 168)
Function: Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20713508, ECO:0000269|PubMed:22882210}; Multi-pass membrane protein. Membrane raft {ECO:0000269|PubMed:20713508, ECO:0000269|PubMed:22882210}; Multi-pass membrane protein {ECO:0000255}. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion. {ECO:0000269|PubMed:20713508, ECO:0000269|PubMed:22882210}.
Interaction partners:
- Iron-uptake system-binding protein
- Iron-uptake system permease protein FeuC
- Uncharacterized protein YbbA
- Iron
- HTH-type transcriptional activator Btr
- Probable siderophore transport system ATP-binding protein YusV
- Fe
- Uncharacterized ABC transporter ATP-binding protein YvrA
- Iron
- Iron
Sequence:
MYSKQWTRIILITSPFAIALSLLLSILYGAKHLSTDIVFTSLIHFDPGNTDHQIIWHSRIPRAAGALLIGAALAVSGALMQGITRNYLASPSIMGVSDGSAFIITLCMVLLPQSSSIEMMIYSFIGSALGAVLVFGLAAMMPNGFTPVQLAIIGTVTSMLLSSLSAAMSIYFQISQDLSFWYSARLHQMSPDFLKLAAPFFLIGIIMAISLSKKVTAVSLGDDISKSLGQKKKTIKIMAMLSVIILTGSAVALAGKIAFVGLVVPHITRFLVGSDYSRLIPCSCILGGIFLTLCDLASRFINYPFETPIEVVTSIIGVPFFLYLIKRKGGEQNG
Protein: Forkhead box protein N3 (Checkpoint suppressor 1) (O00409)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Paired amphipathic helix protein Sin3a
- Menin
- SNW domain-containing protein 1
Sequence:
MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNTPPEIQAGFPPGVIQNGARVLSRGLFPGVRPLPITPIGVTAAMRNGITSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYEFATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN
Protein: Dihydrofolate synthetase (AtDFA) (EC 6.3.2.12) (Protein GLOBULAR ARREST 1) (F4JYE9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Conversion of folates to polyglutamate derivatives, including tetrahydrofolate. Required during embryogenesis; from maternal tissues until the globular stage, and from the embryo after the globular stage.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:11752472}.
Interaction partners:
- Folate synthesis bifunctional protein
- Folate synthesis bifunctional protein
- Bifunctional dihydrofolate reductase-thymidylate synthase 2
- Bifunctional dihydrofolate reductase-thymidylate synthase 1
- Bifunctional dihydrofolate reductase-thymidylate synthase
- Dihydroneopterin aldolase 1
- Dihydroneopterin aldolase 2
- Probable dihydroneopterin aldolase 3
- GTP cyclohydrolase 1
- D-amino-acid transaminase, chloroplastic
Sequence:
MRTLWNHFSTISYIKISPRMRRISAANLISNRNLSTISSTEDPELRDFVGFLESLKNYEKSGVPKGAGTDSDDGFDLGRMKRLMLRLRNPHYKYKVVHVAGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERISCNGEPVSASTLNDLFYSVKPILEQSIQEENGSLSHFEILTGIAFSLFEKENVDIAVIEAGLGGARDATNVIESSNLAASVITTIGEEHMAALGGSLESIAEAKSGIIKHGRPVVLGGPFLPHIEGILRSKAASVSSSVILASNIGSSSSIKGIINKNGIGLCQSCDIVIQNEKDDQPIVELSDVNLRMLGHHQLQNAVTATCVSLCLRDQGCGRVTDEAIRIGLENTRLLGRSQFLTPKEAETLLLPGATVLLDGAHTKESARALKEMIKKDFPEKRLVFVVAMASDKDHVSFAKELLSGLKPEAVILTEADIGGGKIRSTESSVLKESWIKAADELGSRSMEASENKTVLGSLKLAYKILSDDTTSSDSGMVIVTGSLHIVSSVLASLQH
Protein: Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-) (Q9NUW8)
Organism: Homo sapiens (Human)
Function: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate.
Subcellular location: Nucleus {ECO:0000269|PubMed:15647511}. Cytoplasm {ECO:0000269|PubMed:15647511}.
Interaction partners:
- DNA ligase 3
- DNA topoisomerase 1
- DNA repair protein XRCC1
- Aprataxin
- DNA polymerase beta
- Bifunctional polynucleotide phosphatase/kinase
- Tyrosyl-DNA phosphodiesterase 2
- Poly [ADP-ribose] polymerase 1
- Aprataxin and PNK-like factor
- DNA repair nuclease/redox regulator APEX1
Sequence:
MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESMLTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVPS
Protein: WH2 domain-containing protein (Q8WT46)
Organism: Caenorhabditis elegans
Interaction partners:
- CRIB domain-containing protein
- Unconventional myosin-Ie
- WH1 domain-containing protein
- EF-hand domain-containing protein
- Actin-related protein 2
- Amphiphysin
- PPM-type phosphatase domain-containing protein
Sequence:
MPPPPPPPPPPPPPPPPAASAPPPSSNARNALLGDIHKGLKLKKTVTNDRSAPSVGKVVGSSGSSSNGNSGNGNGPAAKPPQMSGGLGGLFANGMPMKPSENKIRRATTSIGPPPTASSAPPVPPPAPVPAVEGKKPSIVSSSSFSHHGATSSAPPPPPPPPPVSVPSSKPTPPPPPPAQQKPSFQSDREQFRTMRPLRPANDVKPTMYRRSGSSEDIPQATSATRLARPLAPPPARPAAPPPPVPTPSIAQMSSRFQSPAISRTLDDAPPPPPRIASKTSVAPTSSRAPLPPSSSFAPSISASPAPAPPPPPPQAASPYPGMKSTATVSANVPFHPLNRFHFLPLSQLPPPPKVSSGSIRA
Protein: Histamine H4 receptor (H4R) (HH4R) (AXOR35) (G-protein coupled receptor 105) (GPRv53) (Pfi-013) (SP9144) (Q9H3N8)
Organism: Homo sapiens (Human)
Function: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist).
Subcellular location: Cell membrane {ECO:0000269|PubMed:34439793}; Multi-pass membrane protein.
Interaction partners:
- Histidine decarboxylase
- Tropomyosin alpha-3 chain
Sequence:
MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
Protein: Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Cytosolic acetoacetyl-CoA thiolase) (Q5XI22)
Organism: Rattus norvegicus (Rat)
Function: Involved in the biosynthetic pathway of cholesterol.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9BWD1}.
Interaction partners:
- Hydroxymethylglutaryl-CoA synthase, mitochondrial
- Hydroxymethylglutaryl-CoA synthase, cytoplasmic
- Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
- Trifunctional enzyme subunit alpha, mitochondrial
- Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
- Peroxisomal bifunctional enzyme
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Citrate synthase, mitochondrial
- Peroxisomal acyl-coenzyme A oxidase 3
- Peroxisomal acyl-coenzyme A oxidase 1
Sequence:
MNAGSDPVVIISAARTAIGSFNGALSTVPVHNLGTTVIKEVLQRAKVAPEEVSEVIFGHVLTAGCGQNPTRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAAQSIAMGDSTIVVAGGMENMSKAPHLAHLRSGVKMGEVPLADSILCDGLTDAFHNYHMGITAENVAKKWQVSREAQDKVAVVSQNRAEHAQKAGHFDKEIVPVHVSSRKGLTEVKIDEFPRHGSNLEAMSKLKPYFLTDGTGTVTPANASGMNDGAAAVVLMKKTEAESRMLKPLAQVVSWSQAGVEPSVMGVGPIPAIKQAVAKAGWSLEDVDVFEINEAFAAVSAAIAKELGLSPEKVNIDGGAIALGHPLGASGCRILVTLLHTLERVGGTRGVAALCIGGGMGIAMCVQRG
Protein: Probable membrane metalloprotease ARASP2, chloroplastic (EC 3.4.24.-) (O23053)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Metalloprotease essential for chloroplast and plant development. May be involved in regulated intramembrane proteolysis (RIP).
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- ATP-dependent protease La
- Putative chloroplast RNA binding protein family protein)
- Pentatricopeptide repeat-containing protein At1g01970
- Mitochondrial transcription termination factor family protein
- Peptidyl-prolyl cis-trans isomerase CYP26-2, chloroplastic
- At2g27680/F15K20.22
- Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic
- Peptidyl-prolyl cis-trans isomerase FKBP17-2, chloroplastic
- Probable inactive ATP-dependent zinc metalloprotease FTSHI 4, chloroplastic
- Thylakoid lumenal protein TL20.3
Sequence:
MLLNISSSPISHRIPHFLSDFNNPTSNFPPKSKTHLPKSNLSTLSNHSLYGTKNRAFYKNKRNPYNRTQALGRFDFGSLESVLEASAVLTAIIVVHETGHFLAASLQGIRVSKFAIGFGPILAKFNSNNVEYSLRAFPLGGFVGFPDNDPDSDIPVDDRNLLKNRPILDRVIVVSAGIVANVIFAYAIIFTQVVSVGLPVQESFPGVLVPDVKSFSAASRDGLLPGDVILAVDGTELSNSGSDSVSKVVDVVKRNPEHNVLLRIERGKESFEIRITPDKSFDGTGKIGVQLSPNVRFGKVRPKNIPETFSFAGREFFGLSYNVLDSLKQTFLNFSQTASKVAGPVAIIAVGAEVARSNADGLYQFAALLNLNLAVINLLPLPALDGGTLALILLEAVRGGRKLPLEVEQGIMSSGIMLVLFLGLFLIVKDTLNLDFIKEML
Protein: Endolysin (F1BCP4)
Organism: Acinetobacter phage phiAB2
Interaction partners:
Sequence:
MILTKDGFSIIRNELFGGKLDQTQVDAINFIVAKATESGLTYPEAAYLLATIYHETGLPSGYRTMQPIKEAGSDSYLRSKKYYPYIGYGYVQLTWKENYERIGKLIGVDLIKNPEKALEPLIAIQIAIKGMLNGWFTGVGFRRKRPVSKYNKQQYVAARNIINGKDKAELIAKYAIIFERALRSL
Protein: Growth hormone receptor (Q0R5T7)
Organism: Bos taurus (Bovine)
Interaction partners:
Sequence:
EGKLEEVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEKSLNIFGAKDDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDAAPASQQPSVILVEENKPRPLLIGGTESTHQAVHTQLSNPSSLANIDFYAQVSDITPAGNVVLSPGQKNKTGNPQCDTHPEVVTPCQANFIVDTAYFCEVDAKKYIALAPHVEAESHVEPSFNQEDIYITTESLTTTAGRSGTAEHVPSSEIPVPDYTSIHIVQSPQGLVLNATALP
Protein: Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80) (C-type lectin domain family 5 member C) (Q9NZS2)
Organism: Homo sapiens (Human)
Function: Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- C-type lectin domain family 2 member B
- SLAM family member 6
- CD160 antigen
- C-type lectin domain family 1 member B
- Natural cytotoxicity triggering receptor 1
- Natural killer cells antigen CD94
- CD226 antigen
- C-type lectin domain family 2 member A
- Natural cytotoxicity triggering receptor 2
- Natural cytotoxicity triggering receptor 3
Sequence:
MQDEERYMTLNVQSKKRSSAQTSQLTFKDYSVTLHWYKILLGISGTVNGILTLTLISLILLVSQGVLLKCQKGSCSNATQYEDTGDLKVNNGTRRNISNKDLCASRSADQTVLCQSEWLKYQGKCYWFSNEMKSWSDSYVYCLERKSHLLIIHDQLEMAFIQKNLRQLNYVWIGLNFTSLKMTWTWVDGSPIDSKIFFIKGPAKENSCAAIKESKIFSETCSSVFKWICQY
Protein: Uncharacterized protein (A0A1D8PRT2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Anaphase promoting complex subunit
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
- Anaphase promoting complex subunit 1
- Anaphase promoting complex subunit
- Anaphase promoting complex subunit
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 2
- Protein kinase
- Spindle assembly checkpoint component MAD2
Sequence:
MEHNKKLGVTHAIREKLNFHDERLWKRFSARRLELIDTLDLSSRKASEQESEIRRVSEMLRLEFDYPASYTSDFNKLVRAAIQSVRRNRKRSSKKHTSPEEPSLKRNKLDDSDSNGNVNGSNSNSFLSEIVRNEDDVYDVNYNREKRFTSDDQAKDTIDNMTKPRLPPLTNLSMNETINIPSAAAAKKNILNKIEKSRSCNESVNSKSENLQFLGKSVMSTCIGYIFEKSFSHVNPQSMLYLRNKLSSELSLSKFFRQLDPVNTNGINDETAVISLYILLGAMVKDFGFEEVIFPICEILYASVLQEYPLMAKNSIPFRNEDQHLGSNNIAYPSENDVYSLNKLAEVASHLQNTGSDTSMSTMEPSRSVTPTSSLTGSYKKRVYLKFFNQKLEFLYPVRIAATPRYNELLENAKSAFKLPDTTIVFKHHGKIVQSDLELERVFKSDEDEIELEISTHNPMPIYEMHKRLSQQDYQQPTESQRIILPPPIASNTAMSNGSSLNSRLGSFNFLSNSDDVPGPKPLHPQQSILPKFQPLL
Protein: Methylcytosine dioxygenase TET (EC 1.14.11.80) (F1R3C6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
- G/T mismatch-specific thymine DNA glycosylase
- G/T mismatch-specific thymine DNA glycosylase
- DNA
- E3 ubiquitin-protein ligase UHRF1
- O-linked N-acetylglucosamine
- DNA
- Methyl-CpG-binding domain protein 4
- Activation-induced cytidine deaminase.
- AT-rich interactive domain-containing protein 4B
- Methyl-CpG-binding protein 2
Sequence:
MSTLILLQTGSITLKVQFLRRPQYCFSCRLSQTPPPSPSLTSAMPRTAKAPKKSTRASTKRNVKRVKASMTRRQTINSLKASGEIKKGIDKKQAAKRAQRTVVSKPNKKTVEDVLPVKISRHTTSSLNQNGLLLECNGKGKSPRKSVSCPSIQRDVQKKGAQEIREQETETKRSEVNDPNGDAEQQKGAEIPTGEGQSVNISSKESGEEHRETVVNDTLVAEKKKVKVNTETVQSESYSAVVEQPNTVFVDQQDPLKHNPVNNVDFAYNNNTSGPPTPSPSDQVEAIQPTLPPVDLQDISLQTTRGNSTEEGETAESSLPNQVCHSSNDSPALENIADANQIEETELRSTADVDTKDESIDAEMLMKKEGALSLLSLSAAIYNTTLCEMGHGPQATALLSSSTESTQSSFDSESELVLEHRTSGKSIPQVEDIQLRLLQDQQRREQNKRGHCGVCAPCQCKVNCGECRSCLNQKTDHQICRLRRCIKLRKKTLIICTGKVESEANSVNGTSSEQMEETCAAPEEEAHYIPVTHNVPPDIITPLQHGLLPEPHGKDPGTTDVLLPHSFSSTSHNGAEHIKSNAQRYVDPTETPANFHSSTINNRHAPEVVQEQMVPLKKIKLEEQQLEIDDQHSKHLETNGCYEDALSTLAAVVCFSSTDRKSLEEKLFGSQTSDVCLKTEPKEEPYQCQLNQEEPPQNDYIALSLPTVQSLVQHRNISVDQAIAIEALTQLAAIPQTVPFKTENQIQDAQQETSTYSAPSNHIPIREAKPATDVVSNKVSVISSSLHQTSVIRSSLNTPTNFTQSQRCAPPPRKLSLKDLLMASSECEKLSYTTENRRNGQALCKSDRLEGTFKMYRHGEATPIYRKKDEEEVAAQLVQLAFMIESRQAQVSENSPPNGMATQSLKYNQNYLGQHLKKQRKPKMTPSNPRMSKKKVAEIDDNHCRILLAKKTPNKKTPLKATIQKAISQHKMRFQHKRNPFLPQAQIDLKKYIAEAQHENRQLLYYNTKKEHLETFIGSGRQNGFHVKYEHGGHSLPPQNGHFYNHTNDHLGASQCPRHECEQKVSQVSKTYDVLNPGAKQQLLQTMANEPFKDLPQIPEMYHKANGFNGHQHLHTNQNGFYKVEKSGGVTVLSASSVHSENGDMVYAGEQTPTKHTINSFLESPMRFLDTPTRNLINTPSKQSMEIPSCDCVEHIIEKEEGPYYTHLGSGPNVAAVREMMETRYGEKGNAVRVEVVVYTGKEGRSSQGCPIAKWIIRRGSEQEKLLCLVRQRAGHCCQNAVIVILILAWEGIPRSVADRLYQELTQTLCKYGSPTSRRCALNEDRTCACQGLDPETCGASFSFGCSWSMYFNGCKFARSKTPRKFRLQGDSPKEEGRLEKNLQNLASDLAPVYKRLAPKAFHNQVEQEQRGQDCRLGCREGRPFSGVTACVDFCAHAHKDTHNMTNGSTVVCTLTKEDNRAVRNIPEDEQLHVLPLYKISDTDEFGKVEGQWAKIKTGALQVLSAFPREVRLLAEPVKSAHKRRLEAKRAHVEKLNSLGSKQVTPVKMKNESPKGFKQTSTENSSFSEKNSPNLSSTMRVPDIGGQYSPLHSGGSYNQSNSCRTPPVGSSFGTSTLPKFPHDPSGGTTHFNGSPPFRHGTIKQEPFRNDPVRTNPKFKSEPEEMRCFQGGAAPTPLSPPMAEGLHSRLNITAQPVTPEVAKAEEVWSDSEHNFLDKNIGGVAVAPSHGSILIECARRELHATTPILRPDRTHPTRISLVFYQHKSLNAPGHGLQQWEAKRAEKAREKEQAERLGLNNQSEPVDSDTDSENETCLDERHKFQVPTRQSLTVSRDSLVMSAPYALTHVTGPYNRWT
Protein: T-box transcription factor TBX6 (T-box protein 6) (P70327)
Organism: Mus musculus (Mouse)
Function: T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Mesogenin-1
- Protein Wnt-3a
- Mesoderm posterior 2
- Recombining binding protein suppressor of hairless
- Fibroblast growth factor receptor 1
- Homeobox protein MOX-1
- T-box transcription factor T
- Protein ripply2
- Homeobox protein MIXL1
- Fibroblast growth factor 8
Sequence:
MYHPRELYPSLGTGYRLGHPQPGADSTFPPALTEGYRYPDLDTSKLDCFLSGIEAAPHTLAAAAPLPLLPSALGPETAPPPPEALHSLPGVSLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRATQLCSQHWGGVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPVATEACGSGDTPGGPCDSTLGGDIRDSDPEQAPTPQEAASASAPPCGGPSAEAYLLHPAAFHGAPSHLPARTPSFAEAPDPGRPAPYSAAFLDLQPGPGGSAYQAAPSVPSFAPHFIQGGPFPLPYPGPGGYLDMGSKPMY
Protein: Interleukin 27 (D3ZPW3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Paralemmin 3
- Cytokine receptor-like factor 1
- Interleukin-6 receptor subunit beta
- Interleukin-27 subunit beta
- Signal transducer and activator of transcription 1
Sequence:
MGQVTGGLGWRLSLLLLPLLMVQTGSWGFPADPLSLQELRREFTVSLYLARKLLSEVQGYVHSFAESRLPGVNLDLLPVGHHLPNVSLTFQAWRHLSDSDRLCFLATTLRPFPALLGGLETQRTWTSSEREQLWAMRLDLRDLHRHLRFQVLAVGFSCSEEEKEEEEEDEEEEEGKELLLGALGGPNQVSSQVSWPQLLYAYQLLHSLELVLSRAVRDLLLLSLPRRPDSACDP
Protein: Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain p190) (Myosin-V) (Q02440)
Organism: Gallus gallus (Chicken)
Function: Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000305}.
Interaction partners:
- Calmodulin
- small monomeric GTPase
- Uncharacterized protein
- Actin, alpha cardiac muscle 1
- Calmodulin, striated muscle
- Actin, cytoplasmic 1
- Uncharacterized protein.
- Ras-related protein Rab-11A
- Uncharacterized protein.
- Unconventional myosin-VI
Sequence:
MAASELYTKYARVWIPDPEEVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDPKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAIPPKHDPLTIFCDLMGVDYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKALHSTVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKKFKLLPELFQDEEKAISPTSATPSGRVPLSRTPVKPAKARPGQTSKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRAACIRIQKTIRGWLMRKKYMRMRRAAITIQRYVRGHQARCYATFLRRTRAAIIIQKFQRMYVVRKRYQCMRDATIALQALLRGYLVRNKYQMMLREHKSIIIQKHVRGWLARVHYHRTLKAIVYLQCCYRRMMAKRELKKLKIEARSVERYKKLHIGLENKIMQLQRKIDEQNKEYKSLLEKMNNLEITYSTETEKLRSDVERLRMSEEEAKNATNRVLSLQEEIAKLRKELHQTQTEKKTIEEWADKYKHETEQLVSELKEQNTLLKTEKEELNRRIHDQAKEITETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKDEMNLMVSIPKPGHKRTDSTHSSNESEYTFSSEITEAEDLPLRMEEPSEKKAPLDMSLFLKLQKRVTELEQEKQSLQDELDRKEEQALRAKAKEEERPPIRGAELEYESLKRQELESENKKLKNELNELQKALTETRAPEVTAPGAPAYRVLLDQLTSVSEELEVRKEEVLILRSQLVSQKEAIQPKEDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKKSHENELESLRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINGIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTPRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIIRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRTIQLRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV