wanglab/gogpt-training-data huggingface dataset:
Protein: Dynein light chain Tctex1 (O64980)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Interaction partners:
- Dynein light chain roadblock
- Dynein light chain
- Dynein light chain
- Dynein light chain
- FAP133
- Axonemal inner arm dynein I1/f subunit
- Dynein light chain roadblock
- Inner arm dynein light chain
- Mr19,000 outer arm dynein light chain
- Uncharacterized protein
Sequence:
MEGVDPAVEEAAFVADDVSNIIKESIDAVLQNQQYSEAKVSQWTSSCLEHCIKRLTALNKPFKYVVTCIIMQKNGAGLHTAASCWWDSTTDGSRTVRWENKSMYCICTVFGLAI
Protein: BCL2-like 1 (Bcl-2-like protein 1) (Bcl-XL-like protein 1) (Bcl2l protein) (Q90Z98)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- BCL2 associated agonist of cell death b isoform 1
- Beclin-1
- BCL2-like 11
- Uncharacterized protein LOC767645
- Cellular tumor antigen p53
- Caspase-9
- Serine/threonine-protein phosphatase PGAM5, mitochondrial
- BCL2-associated agonist of cell death a.
- BCL2-interacting protein 3.
- Cytochrome c
Sequence:
MSYYNRELVVFFIKYKLSQRNYPCNHIGLTEDTNRTDGAEENGEGAAGATTLVNGTMNRTNASSTGTPPQSPASSPQRQTNGSGGLDAVKEALRDSANEFELRYSRAFNDLSSQLHITPATAYQSFESVMDEVFRDGVNWGRIVGLFAFGGALCVECVEKEMSPLVGRIAEWMTVYLDNHIQPWIQSQGGWERFAEIFGKDAAAESRKSQESFKKWLFAGMTLLTGVVVGGLIAQKRL
Protein: Signal peptidase I (SPase I) (EC 3.4.21.89) (Leader peptidase I) (P9WKA1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Ribonuclease HII
- Acyl-CoA:diacylglycerol acyltransferase
- Large ribosomal subunit protein bL19
- Elongation factor 4
- Protein translocase subunit SecA 1
- Uncharacterized protein Rv2901c
- Secreted protein
- Protein translocase subunit SecY
- Protein translocase subunit SecE
- Lipoprotein signal peptidase
Sequence:
MTETTDSPSERQPGPAEPELSSRDPDIAGQVFDAAPFDAAPDADSEGDSKAAKTDEPRPAKRSTLREFAVLAVIAVVLYYVMLTFVARPYLIPSESMEPTLHGCSTCVGDRIMVDKLSYRFGSPQPGDVIVFRGPPSWNVGYKSIRSHNVAVRWVQNALSFIGFVPPDENDLVKRVIAVGGQTVQCRSDTGLTVNGRPLKEPYLDPATMMADPSIYPCLGSEFGPVTVPPGRVWVMGDNRTHSADSRAHCPLLCTDDPLPGTVPVANVIGKARLIVWPPSRWGVVRSVNPQQGR
Protein: Phosphodiesterase 4B, cAMP specific (G3UWT3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQFLPACEV
Protein: Potassium-transporting ATPase subunit beta (Gastric H(+)/K(+) ATPase subunit beta) (Proton pump beta chain) (gp60-90) (P18434)
Organism: Sus scrofa (Pig)
Function: The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (By similarity). Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation of the alpha subunit that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2). Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle.
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:P20648}; Single-pass type II membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:21224846}; Single-pass type II membrane protein {ECO:0000255}. Note=Localized in the apical canalicular membrane of parietal cells. {ECO:0000250|UniProtKB:P20648}.
Interaction partners:
- Potassium-transporting ATPase alpha chain 1
- Sodium/potassium-transporting ATPase subunit alpha
- inorganic diphosphatase
- inorganic diphosphatase
- Sodium/potassium-transporting ATPase subunit alpha-1
- Sodium/potassium-transporting ATPase subunit alpha.
- Protein ADP-ribosylarginine hydrolase-like protein 1
- Delayed-rectifier potassium channel regulatory subunit KCNS1
- Protein ATP1B4
Sequence:
MAALQEKKSCSQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMSGIFALCIYVLMRTIDPYTPDYQDQLKSPGVTLRPDVYGEKGLDISYNVSDSTTWAGLAHTLHRFLAGYSPAAQEGSINCTSEKYFFQESFLAPNHTKFSCKFTADMLQNCSGRPDPTFGFAEGKPCFIIKMNRIVKFLPGNSTAPRVDCAFLDQPRDGPPLQVEYFPANGTYSLHYFPYYGKKAQPHYSNPLVAAKLLNVPRNRDVVIVCKILAEHVSFDNPHDPYEGKVEFKLKIQK
Protein: Keratin-associated protein 19-4 (Q3LI73)
Organism: Homo sapiens (Human)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Interaction partners:
Sequence:
MSYYGSYYRGLGYGCGGFGGLGYGYGCGCGSFRRLGYGCGFGGNGYGYCRPSCYGGYGFSILLKSYPEDTISEVIRRSFNLTKY
Protein: Cyclin-dependent kinase 2-associated protein (Q6IAV4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSYKPIAPAPSSTPGSSTPGPGTPVPTGSVPSPSGSVPGAGAPFRPLFNDFGPPSMGYVQAMKPPGAQGSQSTYTDLLSVIEEMGKEIRPTYAGSKSAMERLKRGIIHARALVRECLAETERNART
Protein: Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2) (GABAAR subunit alpha-2) (P47869)
Organism: Homo sapiens (Human)
Function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity). The alpha2/beta2/gamma2 receptor exhibits synaptogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity).
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:P26048}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P26048}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P23576}. Cell projection, dendrite {ECO:0000250|UniProtKB:P26048}.
Interaction partners:
- Rho guanine nucleotide exchange factor 9
- Gamma-aminobutyric acid receptor subunit beta-1
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit beta-3
- Gamma-aminobutyric acid receptor subunit beta-2
- Muscarinic acetylcholine receptor M2
- Gamma-aminobutyric acid receptor subunit gamma-1
- Gamma-aminobutyric acid receptor subunit gamma-2
- Gamma-aminobutyric acid receptor subunit alpha-4
Sequence:
MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVLGVSP
Protein: Transcription initiation factor IIF subunit alpha (M0QXD6)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU366044}.
Interaction partners:
Sequence:
IMAFNAADKVNFATWNQARLERDLSNKKIYQEEEMPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLKE
Protein: Indoleamine 2,3-dioxygenase (IDO) (EC 1.13.11.52) (Biosynthesis of nicotinic acid protein 2) (P47125)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the first step in tryptophan catabolism in order to supply de novo nicotinamide adenine dinucleotide (NAD(+)) via the kynurenine pathway. Plays a role in the cellular response to telomere uncapping.
Interaction partners:
- Kynureninase
- Kynurenine formamidase
- 3-hydroxyanthranilate 3,4-dioxygenase
- Kynurenine 3-monooxygenase
- Aromatic/aminoadipate aminotransferase 1
- Nicotinate-nucleotide pyrophosphorylase [carboxylating]
- Nicotinate phosphoribosyltransferase
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
- Glutamine-dependent NAD
- Tryptophan synthase
Sequence:
MNNTSITGPQVLHRTKMRPLPVLEKYCISPHHGFLDDRLPLTRLSSKKYMKWEEIVADLPSLLQEDNKVRSVIDGLDVLDLDETILGDVRELRRAYSILGFMAHAYIWASGTPRDVLPECIARPLLETAHILGVPPLATYSSLVLWNFKVTDECKKTETGCLDLENITTINTFTGTVDESWFYLVSVRFEKIGSACLNHGLQILRAIRSGDKGDANVIDGLEGLAATIERLSKALMEMELKCEPNVFYFKIRPFLAGWTNMSHMGLPQGVRYGAEGQYRIFSGGSNAQSSLIQTLDILLGVKHTANAAHSSQGDSKINYLDEMKKYMPREHREFLYHLESVCNIREYVSRNASNRALQEAYGRCISMLKIFRDNHIQIVTKYIILPSNSKQHGSNKPNVLSPIEPNTKASGCLGHKVASSKTIGTGGTRLMPFLKQCRDETVATADIKNEDKN
Protein: Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8) (P23394)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pre-mRNA-splicing factor SNU114
- Pre-mRNA-splicing helicase BRR2
- Small nuclear ribonucleoprotein E
- Pre-mRNA-splicing factor 8
- U1 small nuclear ribonucleoprotein C
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein F
- Spliceosomal protein DIB1
- Small nuclear ribonucleoprotein G
Sequence:
MARPIDVSQLIAGINKKKGLDENTSGKISKPRFLNKQERSKQERLKENEESLTPTQSDSAKVEIKKVNSRDDSFFNETNDKKRNPSKQNGSKFHFSWNESEDTLSGYDPIVSTRAIDLLWKGKTPKNAAESSYMGKHWTEKSLHEMNERDWRILKEDYAIVTKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATIGVETGSEPLIQQVVEYADNDEDKFKKLKPIVAKYDPPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKYVRKHDPLNSNIFSEAVKNKYNVGKQLSNEIIY
Protein: Spermidine/putrescine ABC transporter, permease protein (Q5LRW2)
Organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Spermidine/putrescine ABC transporter, permease protein
- Spermidine/putrescine ABC transporter, periplasmic substrate-binding protein
- Spermidine/putrescine import ATP-binding protein PotA
- Spermidine/putrescine transport system permease protein PotC
- Opine/polyamine ABC transporter, permease protein
- Putrescine ABC transporter, permease protein
- Spermidine/putrescine import ATP-binding protein PotA
- Putrescine-binding periplasmic protein
- Polyamine ABC transporter, permease protein
- Spermidine/putrescine ABC transporter, permease protein
Sequence:
MIGGFAQCRQVFTRGNPMSIETREARQPWILLSPALTAIMLLLFVPLSFIVVYSFWLRTATGADQVGFYLDNWAEALSDRFYRDILFSTLRIAAITTAVCALMGYPAAYFIARSKGNKAILLLLLMLPFWISYIIRTMSWINILGVSGAFNSVLISLGVISEPIQMLYNETTVILGLVHFLLPFMVLNIYVSLDGIDTNLEAAANSLGATKWQSFLQVTLPLSLPGLAAGGLLCFVLGAGTYITPLVLGGPRDAMFANLVFEAIITQLNWPLGSALSLMLLAVLGALVMIYNRYLGMAQLMKGLG
Protein: E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (Tripartite motif-containing 69) (E7F8P0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- PAT1 homolog 2
Sequence:
MRETPANFQQDQNPETPPILSPSQQESQSRRARRTEQSMSSSLPAQNKMDKQKLRPEIPPRVSKSSAQRLSRDLTCSICLDLFKQPVSLPCDHTFCEACITSYWSGPRVKCQAGSGSCPQCRKVFHGKSYRPNRIVANIVESYCQGMEESGVRLGAVSEPAPTAPLCMRHREELKLYCEEDQELVCLVCGISQDHRAHTLVCVQDAQKRYRASLTTSANALQKELNTALECERETEEEVKKLKDHTADLKQRIEAQFSELHQFLYQEEKLLQVKLKTEERRELIRLDEHKALLSVEISRLRRAVNDIEDKLSEQDPYTLLRSIKGLLQRQPPKFERPTLTPPSLCEGRFAGPLQYRVWKSLKGSIYPVPSAITFNSKTANPWLSLTSSLTCVRYQTFNSSVQDNPQRFNAALSLMGGQGFTKGRHYWEVEVYSSTVWTVGVARESVTRKGVINTMPANGFWTLSLSYGVQYMAGTSPPTLLSLEEPLARIGVYLDYKRGLVSFYNAESMTHLYTFRDTFTETLFPYFNLGFLDKVHENEPLKVFMPKI
Protein: receptor protein serine/threonine kinase (EC 2.7.11.30) (Q95U21)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MELSSASSAHLNGKELPAVPQNSVQTHPRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKINGPSKRNTGKFVNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASADEKIRLDFDEVCV
Protein: p44-23 outer membrane protein (Q2GIM4)
Organism: Anaplasma phagocytophilum (strain HZ)
Interaction partners:
Sequence:
MRSRSKLFLGSVMMSMAIVMAGNDVRAHDDVSALDTGGAGYFYVGLDYSPAFSKIRDFSIRESNGETKAVYPYLKDGKSVKLESHKFDWNTPDPRIGFKDNMLVAMEGSVGYGIGGARVELEIGYERFKTKGIRDSGSKEDEADTVYLLAKELAYDVVTGQTDNLAAALAKTSGKDIVQFANAVKISSPEIDGKVCNGDHAAIKATKGKAYVAELTSTYSNEETTQCSGLGNTSQATGPKSLSGFVNTVKVGEGKNWPRGRASDGSSKNIEGDPNSNAKAVATDLTKLTSDEKTIVAGLLAKTIEGGEVVEIRAVSSTSVMVNACYDLLSEGLGVVPYACVGLGGNFVGVVDGHITPKLAYRLKAGLSYQLSPEISAFAGGFYHQVVAAVSSRRY
Protein: Kinesin heavy chain isoform 5A (EC 5.6.1.3) (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC) (Q12840)
Organism: Homo sapiens (Human)
Function: Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q6QLM7}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q6QLM7}. Perikaryon {ECO:0000250|UniProtKB:Q6QLM7}. Note=Concentrated in the cell body of the neurons, particularly in the perinuclear region. {ECO:0000250|UniProtKB:Q6QLM7}.
Interaction partners:
- Kinesin light chain 2
- Kinesin light chain 1
- Kinesin light chain 4
- Kinesin light chain 3
- Kinesin-1 heavy chain
- Kinesin heavy chain isoform 5C
- Neurofilament light polypeptide
- Neurofilament heavy polypeptide
- Neurofilament medium polypeptide
- Alpha-synuclein
Sequence:
MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPECISYTNSLFQNYQNLYLQATPSSTSDMYFANSCTSSGATSSGGPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQAKLFPLHQETAAS
Protein: Xyloglucan endotransglucosylase/hydrolase protein 20 (At-XTH20) (XTH-20) (EC 2.4.1.207) (Q9FI31)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes xyloglucan endohydrolysis (XEH) (By similarity). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Involved in cell proliferation in the tissue reunion process of wounded inflorescence stems. Maybe a downstream target of NAC071 as a consequence of auxin action in wounded stems.
Subcellular location: Secreted, cell wall {ECO:0000305}. Secreted, extracellular space, apoplast {ECO:0000305}.
Interaction partners:
- NAC domain-containing protein 71
Sequence:
MVSFCGRRFAFLIIFLFAAQYERVYAGSFHKDVQIHWGDGRGKILDNVGNLLSLSLDKFSGSGFQSHQEFLYGKVEVQMKLVPGNSAGTVTTFYLKSPGTTWDEIDFEFLGNISGHPYTLHTNVYTKGTGDKEQQFHLWFDPTVDFHTYCIIWNPQRVIFTIDGIPIREFKNSEALGVPFPKHQPMRLYASLWEAEHWATRGGLEKTDWSKAPFTAFYRNYNVDACVWSNGKSSCSANSSWFTQVLDFKGKNRVKWAQRKYMVYNYCTDKKRFPQGAPPECS
Protein: Probable eukaryotic initiation factor 4A (ATP-dependent RNA helicase eIF4A) (Q389T9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Sas10 C-terminal domain-containing protein
- Nrap protein domain-containing protein
- RRM domain-containing protein
- BING4 C-terminal domain-containing protein
- RNA helicase
- U3 small nucleolar RNA-associated protein 25
- rRNA biogenesis protein, putative
- KRR1 small subunit processome component
- Probable eukaryotic initiation factor 4A
- CCAAT-binding factor domain-containing protein
Sequence:
MSEFEALGVHQWLSKQCAYMALHHPTPIQKLCIPSILAGKCVVGGAATGSGKTAAFVLPLLQILAEDPYGVFALVLTPSRELAYQILDQFVALGAPLHIRAALAIGGVPHEQQVSVLHGRPHVVVATPGRLKFLLGTFPEARKAFSHLRFLVLDEADRLTTDDMEGDVSDVVELLQPPRPTRRTLLFTATLEQHLVRVEKGGWLERLGISDAAGQLEVHATNTVMNMPDVARKSDNESSGSGNSVGTSYTVADSLRQTYLFIPNMVKLAYLVAALRSVGSDQTTIIFANSCMRCEIVRLTLQLLGFPVCSLNSIISQKHRIDNLATFKLGIARVLVATDIASRGLDIPAVGAVVHYDLPKQSSTYLHRVGRTARAGRKGLSVALITENDVSLVKRLEKKLQCTLELWKVKGVGEKDVLKILDEVSSAKVQAKLQIEDQFGERVETLKAHAAAKKVIRQVKQKKTKNGAFAATPNKRDKMQVGKHLPNLLAGEAGTQTKGVRKPTKRDRNDSPEETSMAGE
Protein: LIM homeobox 2b (LIM/homeobox protein Lhx2b) (B0R107)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Six3
- Sine oculis homeobox homolog 3a.
- Forkhead box protein G1
Sequence:
MNCTGLEVRLTEILGCRSDGNTCYSVSSAATMLFHGLPGGEMHGVMEEMERRGKSDSATISSAIDMGETETNMPSISGDRVALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFETLIQGDFPTHFNHTDVAPNKGLSSTGPLGLSYYNGVNTVQKGRPRKRKSPGPGADLAAYNAALSCNENDGDPMDRDSQYSSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKASDGSNLAGGTPSGPASEISNASMSPSSTPTTLTDLTNPTMPTVTSVLTSVPGSLDVHECRSPSQSTLTSLF
Protein: RE47284p (Q9W4W5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein
- RH03309p)
- MIP01391p)
- GH01837p)
- Antennal dehydrogenase
- RH17287p
- Uncharacterized protein
- RE04130p
- Uncharacterized protein
- FI06485p
Sequence:
MSPPRHILKLSLEEQRQFIDSFDLVISDCDGVVWLLVGWIPNTGAAVNALKAAGKQIKFVSNNSFRSEEDYMEKFRHIGAKNVQEDDIVHPVKTIVRYLKKHKPGERVYSLMSLEANETLRKHNIEFESLQVKEHLTAASLVDHLAIEKPVGAVLFDIHLDLSYVELAKAIRHLQENDDCQLIAGGSDVIMPLAENLNVAGFFDFLEHVKRYTQREATFLGKPSPILGEMFGEMFEIRDCKRCIFIGDTLVQDVQFGKACGFQSLLVLSGCLTKEDMLNAPVEAQPDYYADSLADFTQLLENIQK
Protein: Uncharacterized membrane protein Rv3479 (O06342)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MFPAAVGVLWQSGLRDPTPPGGPHGIEGLSLAFEKPSPVTALTQELRFATTMTGGVSLAIWMAGVTREINLLAQASQWRRLGGTFPTNSQLTNESAASLRLYAQLIDLLDMVVDVDILSGTSAGGINAALLASSRVTGSDLGGIRDLWLDLGALTELLRDPRDKKTPSLLYGDERIFAALAKRLPKLATGPFPPTTFPEAARTPSTTLYITTTLLAGETSRFTDSFGTLVQDVDLRGLFTFTETDLARPDTAPALALAARSSASFPLAFEPSFLPFTKGTAKKGEVPARPAMAPFTSLTRPHWVSDGGLLDNRPIGVLFKRIFDRPARRPVRRVLLFVVPSSGPAPDPMHEPPPDNVDEPLGLIDGLLKGLAAVTTQSIAADLRAIRAHQDCMEARTDAKLRLAELAATLRNGTRLLTPSLLTDYRTREATKQAQTLTSALLRRLSTCPPESGPATESLPKSWSAELTVGGDADKVCRQQITATILLSWSQPTAQPLPQSPAELARFGQPAYDLAKGCALTVIRAAFQLARSDADIAALAEVTEAIHRAWRPTASSDLSVLVRTMCSRPAIRQGSLENAADQLAADYLQQSTVPGDAWERLGAALVNAYPTLTQLAASASADSGAPTDSLLARDHVAAGQLETYLSYLGTYPGRADDSRDAPTMAWKLFDLATTQRAMLPADAEIEQGLELVQVSADTRSLLAPDWQTAQQKLTGMRLHHFGAFYKRSWRANDWMWGRLDGAGWLVHVLLDPRRVRWIVGERADTNGPQSGAQWFLGKLKELGAPDFPSPGYPLPAVGGGPAQHLTEDMLLDELGFLDDPAKPLPASIPWTALWLSQAWQQRVLEEELDGLANTVLDPQPGKLPDWSPTSSRTWATKVLAAHPGDAKYALLNENPIAGETFASDKGSPLMAHTVAKAAATAAGAAGSVRQLPSVLKPPLITLRTLTLSGYRVVSLTKGIARSTIIAGALLLVLGVAAAIQSVTVFGVTGLIAAGTGGLLVVLGTWQVSGRLLFALLSFSVVGAVLALATPVVREWLFGTQQQPGWVGTHAYWLGAQWWHPLVVVGLIALVAIMIAAATPGRR
Protein: Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD antigen CD193) (P51678)
Organism: Mus musculus (Mouse)
Function: Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1.
Subcellular location: Cell membrane; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Eotaxin
- C-C motif chemokine 5
- C-C motif chemokine 24
- C-C motif chemokine ligand 26
- C-C motif chemokine 7
- C-C motif chemokine 2
- C-C motif chemokine 3
- C-C motif chemokine 4
- C-X-C motif chemokine 10
- C-C motif chemokine 8
Sequence:
MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF
Protein: Protein spalt-accessory (Protein spalt-adjacent) (P21750)
Organism: Drosophila melanogaster (Fruit fly)
Function: Likely to be involved in the establishment of the head.
Subcellular location: Secreted {ECO:0000269|PubMed:8601339}.
Interaction partners:
- Insulin-like peptide 4
- LD15563p
- GEO04221p1
- GEO09613p1
- Bearded
- Uncharacterized protein, isoform A
- BARBU
Sequence:
MKLLIALFALVTAVNAQNGFGQVGQGGYGGQGGFGGFGGIGGQAGFGGQIGFTGQGGVGGQVGIGQGGVHPGQGGFAGQGSPNQYQPGYGSPVGSGHFHGTNPVESGHFHENPHEYPEHHGDHHREHHEHHGHHEHHGHHRH
Protein: Cullin 4A (Q7T2C1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Damage-specific DNA-binding protein 1.
- E3 ubiquitin-protein ligase RBX1
- Protein cereblon
- Denticleless protein homolog
- DNA damage-binding protein 2
- Ubiquitin-like protein NEDD8
- Uncharacterized protein.
- COP9 signalosome complex subunit 8
- DDB1- and CUL4-associated factor 11
- Cullin-4B
Sequence:
MAEDVQHQQKSSFNGLSKSAKAGASKKLVIKNFKDRPKLTDSYTEDTWLKLRDAVSAIQNSTSIQYNLEELYQAVENLCSYKVSPMLYKQLRQVCEEHVQAQIHQFREESLDSLSFLKRMNRCWQDHCRQTIMIRSIFLFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDAAVQSRTVQGILEQVERERSGETVDRSLLRSLLGMLSDLQVYKDSFEQRFLSETTRLYAAEGQRLMQERDVPEYLHHVARRLEEENDRVISYLDQSTQKPLIATVEKQLLGEHMTTILQKGLRTLLDENRVCELTLLYELFSKVKGGLTALLQSWREYIKSVGAETVCSPERDREMVQELLDFKDQMDSVTQSCFQRNESFINAMKEAFENFINQRPNKPAELIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQTEPSNIELTVNILTMGYWPSYTPMDVHLPAEMVKLQEVFKLFYLGKHSGRKLQWQPTLGHAVLKTEFKEGKKELQVSLFQTLVLLMFNESDECSVEEIRVATGIEEGELKRTLQSLACGKARVLNKTPRGKEVED