wanglab/gogpt-training-data huggingface dataset:
Protein: Cytohesin 4 (B1AHH5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDLCHPEPAELSSGETEELQRIKWHRKQLLEDIQKLKDEIADVFAQIDCFESAEESRMAQKEKELCIGRKKFNMDPAKGIQYFIEHKLLTPDVQDIARFLYKGEGLNKTAIGTYLGERDPINLQVLQAFVDCHEFANLNLVQALRVVKTKWESV
Protein: Protein Niban 1 (Protein FAM129A) (Protein Niban) (Q3UW53)
Organism: Mus musculus (Mouse)
Function: Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9ESN0}. Membrane {ECO:0000250|UniProtKB:Q9BZQ8}; Lipid-anchor {ECO:0000250|UniProtKB:Q9BZQ8}.
Interaction partners:
Sequence:
MGGSASSQLDEGKCAYIRGKTEASIKNFSPYYSRQYSVAFCNHVRSEVEQQRDLTSQFLKTKPPLEPGTVLYEAELSQFAEDIRKWKDRYIVIKNDFAVESYESKEAYQRGAVPKSRILPAGGKVLTSEEEYSLLSDKHFPDPTASSEKNSQPFVLLPKAFPVYLWQPYLRHGYFCFHEAAEQQKFSALLNDCIRHLNHDYMKQTTFEAQAFLEAVQFFRQEKGHYGSWEMTTGDEVQVLSKLVMEELLPTLQTDLLPKLKGKKNDRKRAWFGLLEEAYNLVQHQVSEGLNALKEECRALTKDLEGTIRSDMDQIVTSKNFLTGKIRAMVAQPAEQCCGESVQPFLASILEELMGPVSSGFSEVRALFEKEVDELSQSFHATQDSAQLKEGLQQLMKLPLDSVKMEPCYTKVTLLPERLLDLQSRFRFPHVDLVVQRTQNYMQELMENAVFTFEQLLSPYLQGEASRIPVAIEKVKLRVLKQYDYDSSTIRKKIFQEALIQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENVYEEILYEILLDETLKVITEAAILKKHNLFEDNMALPSESVSSLTDLKTAMGSNQASPARRVSAILPGAPDNELPSNEVFQEPEEKKEQPGVPGSLAISASSCPSGGDGQVSVDHSAGGPLTVENTAGPLSSHLSEVEAGGTLKDEEPTCQSPEPSAVPGSLKELKKLLTVTVSVESAPVVENDIHNGTPVPQENIKEEESKIHPEASHPAAIQQDSCEEREVREKEAQPLEAEAPGVDLGILPEGRGSTSQSTSGGLTENTSCPGPIEEPFEAQEPAEKVLPAIVSTEDSPQAGGEAEHSVTVTPQEDATLSSNPICPMESNEVAQASGDQEVLGGEDSSALGMDTEQVNDTHEHACQWLVEDTLSTDILAVHDFDVSSPEQPSEEW
Protein: Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase) (Q62967)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11725955}.
Interaction partners:
- Mevalonate kinase
- Isopentenyl-diphosphate Delta-isomerase 1
- Phosphomevalonate kinase
- Geranylgeranyl pyrophosphate synthase
- Similar to isopentenyl diphosphate delta-isomerase type 2.
- isopentenyl-diphosphate Delta-isomerase
- isopentenyl-diphosphate Delta-isomerase
- Farnesyl pyrophosphate synthase
- Lanosterol synthase
- Squalene monooxygenase
Sequence:
MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTAAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTGDGDALPLSLGYKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRVLILVVSAEKKPTGSTVGMQTSVATSTLLKFRAESIVPERMKEMTRCIQEQDFQAFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNAHHGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKTSLATEPSPGGVQYIIATQVGPGPQVLDDPHHHLLGPDGLPQRDL
Protein: Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2) (Q96L46)
Organism: Homo sapiens (Human)
Function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon calcium binding. {ECO:0000250}.
Interaction partners:
- Calpastatin
- Calpain-1 catalytic subunit
- Calpain small subunit 1
- Calpain-6
- Calpain-5
- Calpain-7
- Calpain-2 catalytic subunit
Sequence:
MFLAKALLEGADRGLGEALGGLFGGGGQRREGGGRNIGGIVGGIVNFISEAAAAQYTPEPPPTQQHFTSVEASESEEVRRFRQQFTQLAGPDMEVGATDLMNILNKVLSKHKDLKTDGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYKQYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNNFISCLVRLDAMFRAFKSLDRDRDGLIQVSIKEWLQLTMYS
Protein: PLAC domain-containing protein (Q3UV61)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
RTNGPLPEAIAILVLPPAEGKPRGSLAYKYVIHEDLLPLIGSNNVLLEETDTYEWALKSWSPCSKACGGGIQFTKYGCRRRRDHHMVHRHLCDHKKRPKPIRRRCNQHSCPQPTWVTEEWGACSRSCGKLGLQTRGVQCLLPLSNGTHKAMPAKACLGNRPEAKKPCLRVPCPAQWRTGAWSQCSATCGEGIQQRQVVCRNTSSALGPCEGVKPDMVQICSLPACGGDLQNSTVKAEVQDPVTKTGYREPQSRPLTPEDRISTMEPCVRDRSVFCRMEVLDRYCTIPGYHRLCCESCIKKTSGPNASLALPPTFSTPGSLLPAPKATLEDVKSTRGPTSLEDHRQSQPTQLPDVADRISPVTQYPVTPQMLSPKAFPGNSPATPRRPPQDWTQTAMPTSEGQGQSREEPGHGGTSLPATSPVT
Protein: Stac-like, isoform N (A0A0C4DHC0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MASYNGVLKDYSHSSLNEAFKSQNNVNFKLIKTVSDFSETLSRLYEEHATALQVAVSNYRKKNAELRKERPACHLAIFQAWETFLQEVETDSQACNDVASVLSRQVSRPMLDKSFHRKVQSRKIFTHRESFETIIAKTEEKLSKCRVDYKQCHLAHRQNPSQHSLTEYIDAHNAYVQQLHATNGMLEAYHTDTLPQQMQELEEIHNDLVAIVSDSLMQGAEVIAGKANDQAKRYNSLSNQCAAVSPQQDLVNFVRLLAQPSQAQKIPRRLFASPQAEVGEEAGDHNEMTPCLRNELVFDRHSTLSQRSALESLKREAIELELQIRQLQDSIEALNRTQTRGIEGQLYNKVNELQEDLSMKKFDLRAKQIHLAAIRAQKDLFVSKVEPTSPRNERKFSAATAPSMKTKWLKAFKSLKPAGSGSAQQADRRNGASSTASEPLRPNLDGSHHLQEYTYKKITACDVCSQILRGHTRQGLRCRICKLNAHGDCAPNLPRCQPKQKLLRRQKSTSELENRVDIEEETSANPKSETTRPFGEPLMLLKSTESNPDESKGNRRVR
Protein: Appetite-regulating hormone (Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (Q2V0H4)
Organism: Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
AGSSFLSPAYKNIQQQKNTRKPAARLHRRGTESFWDTDETEGEDDNNSVDIKFNVPFEIGVKITE
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (F8W6N3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ
Protein: Dirigent protein 12 (AtDIR12) (O82498)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism (By similarity). Required for seed accumulation of neolignans.
Subcellular location: Secreted, extracellular space, apoplast {ECO:0000250}.
Interaction partners:
- Dirigent protein 24
- Dirigent protein 16
- Dirigent protein 25
- Dirigent protein 18
- Dirigent protein 9
- Dirigent protein 17
- Cytochrome P450 71B10
- Dirigent protein 10
- Dirigent protein 22
- F1N19.7
Sequence:
MTNQIYKQVFSFFLSVLLLQSSTVSYVPKSFDLKKPCKHFVLYLHNIAYDGDNAANATAATIVKPLGLGDHSFGELIIINNPVTLDQNYLSKPVARAQGFYFYNMKTNYNAWVAWTLVFNSTKHKGTFTIMDANPFGLQPARDLSIVGGTGDFLMTRGIATFKTKLTQGSKYFCVEMNIKLYECY
Protein: Protein LRATD2 (Breast cancer membrane protein 101) (LRAT domain-containing 2) (Protein FAM84B) (Protein NSE2) (Q96KN1)
Organism: Homo sapiens (Human)
Interaction partners:
- Catenin alpha-1
- Uroporphyrinogen decarboxylase
Sequence:
MGNQVEKLTHLSYKEVPTADPTGVDRDDGPRIGVSYIFSNDDEDVEPQPPPQGPDGGGLPDGGDGPPPPQPQPYDPRLHEVECSVFYRDECIYQKSFAPGSAALSTYTPENLLNKCKPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVINSFLTDASQGRRGRVVNDLYRYKPLSSSAVVRNALAHVGAKERELSWRNSESFAAWCRYGKREFKIGGELRIGKQPYRLQIQLSAQRSHTLEFQSLEDLIMEKRRNDQIGRAAVLQELATHLHPAEPEEGDSNVARTTPPPGRPPAPSSEEEDGEAVAH
Protein: DAZ associated protein 1 isoform 1 (DAZ associated protein 1, isoform CRA_a) (Testicular tissue protein Li 50) (A0A0S2Z569)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNNSGADEIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASRPHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRSDNSKSNKIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMHFHDIMGKKVEVKRAEPRDSKSQAPGQPGASQWGSRVVPNAANGWAGQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPPGGFPPPQGFPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQPDFPYGQYAGYGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGPPAGGSGFGRGQNHNVQGFHPYRR
Protein: Nucleolar protein 8 (Q3UHX0)
Organism: Mus musculus (Mouse)
Function: Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250}. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis. {ECO:0000250}.
Interaction partners:
- U3 small nucleolar ribonucleoprotein protein MPP10
- Probable ATP-dependent RNA helicase DDX10
- Box C/D snoRNA protein 1
Sequence:
MQGNREMKRLFVGGLGQGISETDLQNQFGRFGEVSDVEIITRKDDQGNSQKVFAYVNIQITEADLKKCMSILNKTKWKGGTLQIQLAKESFLHRLAQEREDAKAKKEKSTTGNPTLLEKMGAVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQQKHKIMKYDPSKYCHNIKKIPENLTETTPIAELTWELEGGNDPMSKKRRGEFSDFHIPPQKVKKVQKSNDPMESKVSNIGLRTNQVMEKNKSTHPVTAHGTAPSTVNPSKQLLVSSSGTQKPKHVVFHNSDFEIIWNKSSMSDDDVDSEDELKMMIAKEENREKPGHSSVNESEHDTFEVVRDDFKSNIHKLSSSVSLGNNHEYDSSDTDEIIAMKTKNAKVKNSAESSQPERTVSKKSSFQKIEPSNDCIKVQGINSNKESALCHGVKFVNPKFPPDSSGSDSEESEEDEEYKVLMENCPRVSLTLADLEQLAGSHRKFPGKDSETNGPQNDSHCKFDTTSKNPKTSGDLYNGRQQCILPEEIVASLLEDENTYSKQKSEEDILKPKFQAFKGIGCLYAKESVDKTLKENIAFNTGGGHHSSLKHEDHNRSLMENGSKCVNGSSSKLTSCQPAKKVNDPNHIQPPKRQCTFENQNHKVMSSTSCDKGSTNPLPGPLPLKAKTSLHLSANSHKVDSDGDACHWPESRKALEKERTNLSNLESLEKSSKVSPREDPQKSPAGFSLSDSNASCINAKDKQAEDNQKRLAALAAWQKAREVQKKLVHSALANLDGHPEDKKTHIVFASDNESETEETSTQEQSCPEKELMKESVSKSPGKLFDSSDDEDSDSKEDSTRFSIKPQFEGRAGQKLMDLQSQFGSDERFRMDSRFLESDSEDEKKELNEDKVNEDELAAEKKKTLNVVQSVLNINVNNPTNKGSVAAKKFKDIVHYDPTKHDHAIYERKQEDKEKESKATRKKKKEEAEKLPEVSQDMYYNIAADLKEIFQSMSNTDEKEEDVPRTEAGAREGTGKIRNAETLACEPEQTTGFTFSFFDSATKDEKDATYRIELVKHGKIVCPNDPRFQDSSSEEEDIAEEADHSKPSPGEAVPENEAIRFFFFSENDDRLRGSNLFWSGMGGSISRNSWEARTSSLLLECRKKHKEAKRKVKAN
Protein: Large ribosomal subunit protein bL36c (50S ribosomal protein L36, chloroplastic) (P62117)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein bL20c
- Large ribosomal subunit protein uL14c
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS8c
- Small ribosomal subunit protein uS14m
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Large ribosomal subunit protein bL28c
- Small ribosomal subunit protein bS18c
- Large ribosomal subunit protein uL16c
- Small ribosomal subunit protein bS16cz
Sequence:
MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
Protein: Xaa-Pro dipeptidase (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Q38D78)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ribonuclease Z
- Succinate--CoA ligase subunit beta, mitochondrial
- Elongation factor Ts, mitochondrial
- Mitochondrial intermediate peptidase, putative
- Mitochondrial processing peptide beta subunit, putative
- Mitochondrial processing peptidase alpha subunit, putative
- Mitochondrial processing peptidase alpha subunit, putative
Sequence:
MSSNCIRNTAYPFEISPDMYKEQRQRLAASMRTCMDDTHAAFLQGSSEVPVNSTDVNHLFWQESYFAYLFGCDIPDCFGAVLTDGTGILFIPRLPASYAVWMGELPTPASVKEATGVEEVYYTDEINETFAAKGVTTVEVMKGVNSDSGLNVLTAQLPQPSKLNTSTDFLFDTLSRQRCYKTDLEIDLLRYVCRVSSDAHIHVMQQCKPGMSQHQLESTFLHHVYYHGGCRKVAYTCICATGHYGAVLHYPNNDAPIEDGSMALLDMGGHYMGYASDITCSFPVNGKFTSDQVMIYNAVLDAHDSVMKSLRPGTNWVDMHKLALRVMCKHLLRAGLLMGDVDTIMQKRIMGLFQPHGLGHLLGMDVHDVGGYLEDCPKRPVESDCCKLRTARVLEKGMCLTVEPGCYINRSLLTDAFVNPEMKPHLHEEGLRKLWNFGGVRIESDVVITETGVVNLTVVPRTVEEIERTMAGVPFVGEPVVFVNQKNAP
Protein: Photosystem II reaction center protein I (PSII-I) (PSII 4.8 kDa protein) (P0C407)
Organism: Oryza sativa subsp. japonica (Rice)
Function: One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01316}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01316}.
Interaction partners:
- Photosystem II reaction center protein J
- Photosystem II reaction center protein L
- Photosystem II reaction center protein K
- Cytochrome b559 subunit beta
- Photosystem II reaction center protein T
- Photosystem II reaction center protein H
- Cytochrome b559 subunit alpha
- Photosystem II CP47 reaction center protein
- Photosystem II CP43 reaction center protein
- Photosystem II protein D1
Sequence:
MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGRDE
Protein: Dihydroxyacetone kinase 1 (DHA kinase 1) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase 1) (Triokinase 1) (Triose kinase 1) (O13902)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.
Interaction partners:
- Glycerol dehydrogenase 1
- Triosephosphate isomerase
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- Fructose-bisphosphate aldolase
- Dihydroxyacetone kinase 2
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase [NAD
- Uncharacterized acyltransferase C1718.04
Sequence:
MDKHFINDPEVLVLDGLKSLADMNKTLTVHEEGKFIYFHDYNKKNVSVISGGGAGHEPTHSSFVGKGMLTAAVSGSIFASPSSKQIYTGIKQVESEAGTLVICKNYTGDILHFGMALEKQRTAGKKAELIAVADDVSVGRKKSGKVGRRGLSGTVLVHKIAGAAAARGLPLEAVTTIAKAAIDNLVSIGASLAHVHVPGHEPIAKEDEMKHDEMELGMGIHNEPGCKRISPIPSIDDLIAQMLKQMLDQSDKDRAYVKIEGDDEVVLLMNNLGGLSMLEFSAISHKVKEALAKEYKINPVRIFAGPFTTSLNGLGFGITLLRTTDRVKVEGEEYSLVDLIDQPVEAIGWPLCQPSDLKSKNKIGNVSIEEGQKDVKSPVTVDKEKVRQAIVNSMENLIKAEPKITKFDTMAGDGDCGTTLKRGAEGVLKFVKSDKFSDDPIRIVRDIADVIEDNMDGTSGALYAIFFHGFAKGMKDTLEKSKDISSKTWAAGLKVALDTLFKYTPARPGDSTMCDALVPFVETFVKTNDLNAAVEEARKGADATADMQAKLGRAVYVGDDVKVPDAGALGVVAIVEGFTK
Protein: MMP28 protein (Matrix metallopeptidase 28) (C0H5X0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVARVGLLLRALQLLLWGHLDAQPAERGGQELRKEAEAFLEKYGYLNEQVPKAPTSTRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFLPRRGEAHFDQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGRDALLSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYCHSSFDAITVDRQQQLYIFKGSHFWEVAADGNVSEPRPLQERWVGLPPNIEAAAVSLNDGDFYFFKVQSV
Protein: Huntingtin interacting protein 1 related (Q99PW9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
RAEPGRDRVGGSMNSIKNVPARVLSRRPGHSLEAEREQFDKTQAISISKAINSQEAPVKEKHARRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHLRDQYGHLVNIYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLMFKLHSCLPADTLQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPVVVIPEEAPEEEEPENLIEINSGPPAGEPVQVVADLFDQTFGPPNGSMKDDRDLQIENLKREVETLRAELEKIKMEAQRYISQLKGQVNSLEAELEEQRKQKQKALVDNEQLRHELAQLKALQLEGARNQGLREEAERKASATEARYSKLKEKHNELINTHAELLRKNADTAKQLTVTAEQEEVARVKEQLAFQMEQVKRESEMKMEEQSDQLEKLKRELVAKAGELAHAQEALSRTEQSGSELSSRLDTLNAEKEALSGAIRQREAELLAAQSLVREKEEALSQEQQRAQEKGELQGRLAEKESQEQGLQQKLLDEQFAVLRGAAAEAEAILQDAVSKLDDPLHLRCTSSPDYLVSRAQAALDSVSGLEKGHTQYLASSEDASALVAALTRFSHLAADTIVNGGATSHLAPTDPADRLIDTCRECGARALELMGQLQDQTKLPRAQPSLMRAPLQGILQLGQDLKPKSLDVRQEELGAMVDKEMAATSAAIEDAVRRIEDMMNQARHESSGVKLEVNERILNSCTDLMKAIRPLVMTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVESADKVVLHMGKYEELIVCSHEIAASTAQLVAASKVKANKNSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDRDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERVRLGELRKQHYVLAGGMGTPGEEEPSRPSPAPRSGATKKPPLAQKPSIAPRPDNQLDKKDGVYPAQLVNY
Protein: DNA topoisomerase small subunit (EC 5.6.2.2) (DNA topoisomerase 18-kDa subunit) (Protein Gp60) (P23992)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Small subunit of the DNA topoisomerase that untwists superhelical DNA. Controls topological states of double-stranded DNA by transient breakage and subsequent rejoining of DNA strands.
Interaction partners:
Sequence:
MKFVKIDSSSVDMKKYKLQNNVRRSIKSSSMNYANVAIMTDADHDGLGSIYPSLLGFFSNWPELFEQGRIRFVKTPVIIAQVGKKQEWFYTVAEYESAKDALPKHSIRYIKGLGSLEKSEYREMIQNPVYDVVKLPENWKELFEMLMGDNADLRKEWMSQ
Protein: Uncharacterized transporter C1B3.15C (O13879)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MDTNTLPPKPSISPSIASSFPTVKPFSSQNSTTSNPELSHIEKESNASSIIISQQPLSPSNISSAAPLDETHIATKASASLRNNNVSPHIPSPSSFSSSSSSDLDKSMLDEKHPDSEDITAVSLSTPPFPESIDVARFSSEEKKILSRIRRKLDLRIITCLWITYFLSRSVTYSISLSLTMNKHQGHSLLQTVSGLNYHTLSVGTGLSYVSLIIFDLPSNLLMTRADPRLWLSRIQVTTGIIGACHAVLGTKGSSASGFIALRFFNGLAIAGMWPGFAFYTSRFYRDQHLGKRIGWYYTAAQISSVATSLLSAAFQKMDGLHGLYGYQWMFLIWGVVAFTQGLFLPRWLPCIKHNQHNEKWISWIRIPKFLGFLKASENTGLTPEEEEVHAIYMAEMQVGKSWTLTDLADAFLDVRLWPPIFMFFGVVGISNGLVNYSSLIISEINENFSSVTVSLLVAPIWVFDAIAILTVLPLHDRFHKKMLFFVGSCLFVLAGLLITTFVSNVWGRYVGLLILGFGLGPTVPIIMTWVSSAMGPSHGDVGVAAGLAIVSGLGNLGSVVATSALYSGWKADTTFRRSNETMCGMVGIAIVASIVMHMVQKFNIRRFPFKRIYACLSERRKKELSVT
Protein: Auxin efflux carrier component 1 (Protein PIN-FORMED) (AtPIN1) (Q9C6B8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a component of the auxin efflux carrier. Seems to be involved in the basipetal auxin transport. Mediates the formation of auxin gradient which is required to ensure correct organogenesis. Coordinated polar localization of PIN1 is directly regulated by the vesicle trafficking process and apical-basal PIN1 polarity also depends on the phosphorylation of conserved serine residues by PID kinase. The ARF-GEF protein GNOM is required for the correct recycling of PIN1 between the plasma membrane and endosomal compartments.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20439545, ECO:0000269|PubMed:33705718}; Multi-pass membrane protein {ECO:0000305}. Note=Localized the plasma membrane in a polar basal localization. {ECO:0000269|PubMed:33705718}.
Interaction partners:
- ABC transporter B family member 19
- ABC transporter B family member 1
- Protein kinase PINOID
- Auxin transporter-like protein 2
- Auxin transporter protein 1
- KIB1-4 beta-propeller domain-containing protein
- Auxin transporter-like protein 3
- ABC transporter B family member 4
- Serine/threonine-protein kinase D6PK
- AP2-like ethylene-responsive transcription factor PLT2
Sequence:
MITAADFYHVMTAMVPLYVAMILAYGSVKWWKIFTPDQCSGINRFVALFAVPLLSFHFIAANNPYAMNLRFLAADSLQKVIVLSLLFLWCKLSRNGSLDWTITLFSLSTLPNTLVMGIPLLKGMYGNFSGDLMVQIVVLQCIIWYTLMLFLFEYRGAKLLISEQFPDTAGSIVSIHVDSDIMSLDGRQPLETEAEIKEDGKLHVTVRRSNASRSDIYSRRSQGLSATPRPSNLTNAEIYSLQSSRNPTPRGSSFNHTDFYSMMASGGGRNSNFGPGEAVFGSKGPTPRPSNYEEDGGPAKPTAAGTAAGAGRFHYQSGGSGGGGGAHYPAPNPGMFSPNTGGGGGTAAKGNAPVVGGKRQDGNGRDLHMFVWSSSASPVSDVFGGGGGNHHADYSTATNDHQKDVKISVPQGNSNDNQYVEREEFSFGNKDDDSKVLATDGGNNISNKTTQAKVMPPTSVMTRLILIMVWRKLIRNPNSYSSLFGITWSLISFKWNIEMPALIAKSISILSDAGLGMAMFSLGLFMALNPRIIACGNRRAAFAAAMRFVVGPAVMLVASYAVGLRGVLLHVAIIQAALPQGIVPFVFAKEYNVHPDILSTAVIFGMLIALPITLLYYILLGL
Protein: Homeobox protein engrailed-2 (Homeobox protein en-2) (Mo-En-2) (P09066)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus.
Interaction partners:
- Paired box protein Pax-2
Sequence:
MEEKDSKPSETAAEAQRQPEPSSGGGSGGGSSPSDSDTGRRRALMLPEVLQAPGNHQHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGARGGEGGAGTTEGGGGGAGGAEQLLGARESRPNPACAPSAGGTLSAAAGDPAVDGEGGSKTLSLHGGAKKPGDPGGSLDGVLKARGLGGGDLSVSSDSDSSQASATLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE
Protein: tRNA sulfurtransferase (EC 2.8.1.4) (Sulfur carrier protein ThiS sulfurtransferase) (Thiamine biosynthesis protein ThiI) (tRNA 4-thiouridine synthase) (Q9HU66)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00021}.
Interaction partners:
- Cysteine desulfurase IscS
- cysteine desulfurase
- Thiazole synthase
- Ribosomal RNA small subunit methyltransferase B
- tRNA-specific 2-thiouridylase MnmA
- tRNA
- Sulfur carrier protein TusA
- tRNA pseudouridine synthase A
- Molybdopterin-synthase adenylyltransferase
- Sulfurtransferase TusD homolog
Sequence:
MKLIVKTFQEITIKSRPVRKRFIRQLAKNIRAVLRDLDPELKVEGEWDNLEVETAVVDAKARREMIERLTCTPGIGHFLEVHEYPLGDFDDILAKCKAHFGDQLAGKTFAVRCKRAGKHAFTSMEVERYVGSGLRRECGAAGIDLKQPEVEVRMEIRLDRLFVIHRQHPGLGGYPLGALEQVLVLMSGGFDSTVAAYQMMRRGMISHFVFFNLGGRAHELGVMEVAHYLWEKYGRSQRVLFVSVPFEEVVGEILTKVDDSYMGVTLKRMMLRAASRVAERLELDALVTGEAISQVSSQTLPNLSVIDRVTDTLVLRPLIVSHKQDIIDTARQIGTAEFARHMPEYCGVISVNPTTQAKPYRVEHEESKFDMAVLERALERATQRTVDRVIDELGQDLQVEEVGEVLPGQIVIDIRHPDAQEDEPLALEGVEVQALPFYAINSRFKELDANRQYLLYCDKGVMSRLHAHHLLNEGHTNVRVYRPA
Protein: RGS domain-containing protein (Q8T3F0)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MMPPLTKIEVLAKRVMEGAQLKTHKYFRIAVPHAITGQQLIALVLERGAPDDEAEASHLASLLLHHGYMFPVIEHGQPFKDDGTLYRLQRPYFWPSQAELVPDVEYAIYLNKRLLRNEQKHGLEEDEVESFNRLADVLAHMWAFIVQQSELQLKQQKEKKKVDKVVFDSEERAFWKIRKPSRGGPNFLEDPYMKIEKKIRRQNAQGYRCLMDRLRFAIKTKPWLKALKASDTMVTWVDQRAEFDPFLHPPQPSNPWISDEASFWNQPTDTSSAEIPTEKRVKRWGLSVQELVKDPIGRQVLETFLESEFSSENIRFWIAIQDLKYAPNEQIYQKAERIREEFLAQGAPAQVNVDNRTLDQTLECISKAKDASQMRFAFYHSEEHVFTLMAKDSYPRFVRSQIYKAVLTAAQQHGTKRLGWRNFVFNMGNYV
Protein: T. brucei spp.-specific protein (Q38AU4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPHCPRSPLRTHTAPSLPHEQPGSYTATVTLHGERRVADAYASEVCWGGQTGTRWGSTHRGVEQADVWKTALCPQAAFQRRALSLLGEGHTGTRHGLLKEPHLRCCDAGETARPTRHIERHRSPTTVGGDAVQQLGTTLCHSSYCRMPSVNPPATAYERALAKHGKRLLAAVQREQRRKLEEQRNRQVLERRKALYERYTKWNRQSTHKNGSEQTPAAASRCEEVEARQHSALTVTIGASETVGSSPSSLPGGGTLETTLQATKHLLLEHTTEVVGCSTAPFNEPVGGKHNQMPRNTMYPKELQEPQNHNLAECECSTSFMAYLAGRLSPRRRCGGSRFNPGSGGRGDFIHVCWPHCFTPPRPLPCRQVPHEWGRNLVASLATCGDADGEGLRWGLPSPLSCVLPDDIHQTSLRRSPRTAEATALSQRYCTSLDGSVNECAGEERHLLTFMRPMDQPRPLLSYHRPKTICEDQGGAYAASACP
Protein: GH26447p (Glial cell line-derived neurotrophic family receptor-like, isoform K) (Q8IH40)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
Sequence:
MLKPFAVIIGIFYLGSTIKGVVAILNCILARQLCFEDPSCSAILEIIPRVCGPIPVSCSTVTVTKCQAALRTLQAFQFFRPTCLCKEPGMDPDCNHFRDFLFDHPCGFVLKKAEKDPYPIDALPTCNHALSVCQQERKCLKLFEDFKTHCKVRDNKCKMENRDACHDSWTNLRLSPMFGCICPNNHMKKRCDRIFNIVNHNPCVGKFRLAMLNC