wanglab/gogpt-training-data huggingface dataset:
Protein: Calpain-like protease palB (EC 3.4.22.-) (Cysteine protease palB) (Q00204)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).
Interaction partners:
- Vacuolar-sorting protein snf7
- pH-response transcription factor pacC/RIM101
- pH-response regulator protein palC
- pH-response regulator protein palF/RIM8
- pH-response regulator protein palH/RIM21
- pH-response regulator protein palA/RIM20
- Calcium binding modulator protein
- Vacuolar protein-sorting protein bro1
Sequence:
MSRTSSAPSQKSLISRALKAERDVITASSQSQALDAAIDAAEHYMKALALTSSSKDRNVLDAKCKEWLTRAEKIKGSEDWRSVAQSRRSRLRTPASTRKLTTREDIILLQGAKLNGFIFPPWKAEPSLTEFETGTNGDVLFTDKPDLHLSNLQRDIFAGWKRPHELLSGQVDDAGMPLNPVMTVSGNTDLVQDVLTDCSVVASLCATTSRSERGLDDTLLPIVYPCIHNSMKSDISPSGKYIFRFYFNGCFRKVVIDDRLPSSKTSRSLYMIDRNHRNFMWPALVEKAYLKLRGGYEFPGSNSGTDLWVLTGWIPEQVFLHSDEVTADQIWSDLFKSFHSGDVLLTIGTGKLTEREQKELGLVSEHDYAILDMKELKGRRQFLIKNPWAGTDAVYPALFADPGPFPNSPFLSPGTFWMDCEMVLQNFENLYLNWNPGIFAYQEDIHFTWDLSTGKGMAGCFVKNPQFSVYTERGGVVWLLLGRHLRTIESRASEEDERFGFISIYVFKGGKRVALSDGALHRGPYVDSPNTLMKLDVPPRSTYTAVVSEESLPRVSQNFTISAFSDSPVRISHAPNKYICVTKVQGSWTPTTAGGNAESARYSLNPQFSIVLSDPTDISIVLEPSDQELATHVKLFWSGGKRIARVRSRDIVADSGDYRRGGSLVEKQDLDPGEYTIVVSTFAPDQYGSFTLWVSTNITCEVTQLPSEAAGRRAVLSDIGVLLPGQDRMLAPLTTPRLTRVKLIARSRESRIGNRPVGPSPLLMTVELGQGPYKEILATSEDGDHSDSISGVRVEDFDLQPGLEERGGVWIVLERIGGPGGQVEDHFEVEALGEERVEIGEWIVEDA
Protein: Adhesion G protein-coupled receptor E3 (EGF-like module receptor 3) (EGF-like module-containing mucin-like hormone receptor-like 3) (Q9BY15)
Organism: Homo sapiens (Human)
Function: Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils.
Subcellular location: Cell membrane; Multi-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Interaction partners:
- Complement decay-accelerating factor
Sequence:
MQGPLLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEGRKELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMDIRCSDIIQGDTQGPSAIAFISYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPGQVKRKY
Protein: Remorin (DNA-binding protein) (O80837)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Exhibits a non sequence-specific DNA-binding activity.
Interaction partners:
- B3 domain-containing protein REM1
- Syntaxin-32
- Syntaxin-31
- At3g24315
- Centromere/kinetochore protein zw10 homolog
- Putative syntaxin-24
- Membrin-12
- Membrin-11
- VAMP-like protein YKT61
- VAMP-like protein YKT62
Sequence:
MAEEQKTSKVDVESPAVLAPAKEPTPAPVEVADEKIHNPPPVESKALAVVEKPIEEHTPKKASSGSADRDVILADLEKEKKTSFIKAWEESEKSKAENRAQKKISDVHAWENSKKAAVEAQLRKIEEKLEKKKAQYGEKMKNKVAAIHKLAEEKRAMVEAKKGEELLKAEEMGAKYRATGVVPKATCGCF
Protein: Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9) (O77480)
Organism: Bos taurus (Bovine)
Function: Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:9614118}.
Interaction partners:
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase
- Methylenetetrahydrofolate dehydrogenase
- Trifunctional purine biosynthetic protein adenosine-3
- C-1-tetrahydrofolate synthase, cytoplasmic
- Aminomethyltransferase, mitochondrial
- Formimidoyltransferase-cyclodeaminase
- Serine hydroxymethyltransferase, mitochondrial
- Serine hydroxymethyltransferase, cytosolic
- Dihydrofolate reductase
- Methionine--tRNA ligase, cytoplasmic
Sequence:
MRVLLRCCCGHLPVGGGAGRRSNPRWRALARLSASPGWEDGQGARVREKPPWRVLFFGNDQFARETLRALHAARENKEEELIEKLEVVTVPSPSPKGLPVKQYAVQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEAFILKFPYGILNVHPSCLPRWRGPAPIIHTILHGDTIAGVTIMQIKPRRFDVGPILKQETVPVPPKSTSKELEAVLSRLGANMLISVLKNLPESLNNGRQQPAEGVTHAPKISAATSCIKWEEQTSEQIFRLYRAVGNIIPLQTLWMDNTIKLLDLVEVDNSILSDSKLTGQAVIPGSVIYHKQSQILLVCCKDDWIGVRSVMLKKTLTATDFYNGYLHPWYQKNSQAQPSQCRFQTLRLPPKKKQKKKIVAMQ
Protein: DNA-directed RNA polymerase subunit Rpo12 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit P) (Q4JAE8)
Organism: Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00615}.
Interaction partners:
- DNA-directed RNA polymerase subunit Rpo7
- DNA-directed RNA polymerase subunit Rpo6
- DNA-directed RNA polymerase subunit Rpo5
- DNA-directed RNA polymerase subunit Rpo3
- DNA-directed RNA polymerase subunit Rpo10
- DNA-directed RNA polymerase subunit Rpo11
- DNA-directed RNA polymerase subunit Rpo2
- DNA-directed RNA polymerase subunit Rpo1C
- DNA-directed RNA polymerase subunit Rpo1N
- DNA-directed RNA polymerase subunit Rpo4
Sequence:
MAKYRCGKCWKELDDDQLKTLPGVRCPYCGYRIIYMVRKPTVKIVKAI
Protein: Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C) (P0AA39)
Organism: Escherichia coli (strain K12)
Function: Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
Interaction partners:
- Fluoride-specific ion channel FluC
- Ribosomal large subunit pseudouridine synthase B
- Ribosomal large subunit pseudouridine synthase E
- Peptide chain release factor RF2
- RNA pyrophosphohydrolase
- Ribonuclease R
- tRNA pseudouridine synthase D
- tRNA modification GTPase MnmE
Sequence:
MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRKGEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHILVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSALRSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSETRFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTGLNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQKLRNAR
Protein: Small ribosomal subunit protein uS2B (40S ribosomal protein S0-B) (Nucleic acid-binding protein NAB1B) (P46654)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uS2 is required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14627813, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein eS12
- Small ribosomal subunit protein uS4B
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS13A
- Small ribosomal subunit protein uS12A
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS9A
- Small ribosomal subunit protein eS24A
- Small ribosomal subunit protein eS4A
Sequence:
MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTYGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRLDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRNPEEVEQVAEEAAAAEEGEEEEVKEEVTEGQAEATEWAEENADNVEW
Protein: Nuclear pore complex protein NUP93B (Nucleoporin 93B) (F4J284)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:21189294}. Nucleus, nuclear pore complex {ECO:0000305}.
Interaction partners:
- Nuclear pore complex protein NUP205
- Nucleoporin
- Nuclear pore complex protein NUP107
- Nuclear pore complex protein NUP155
- Nuclear pore complex protein NUP54
- Nuclear pore complex protein NUP35
- Protein SEH1
- Aladin
- Nuclear pore complex protein NUP88
- Glutamyl-tRNA
Sequence:
MANDQEMSGWTDLLHSSTKLLEQAAPSSQFPPLQRNLDQLEALSRKLKAKTLRNEAPSQSIAATRLLAREGINADQLSRDLKSFELKTTFEDVFPAETTSVEEYLQQVHEMAMVSAIQEAQKDNVRSFNNYMLKVLEEDCIKEKRDFLHSLSKTSMLPKTKMINSSRGSHAGSLVPLSPQVSSKPGTELVSMTNKPIHEKKAYVYAEVVKKLNSARERGLPFKLATLFNGAYESLEIDLTRGKSVNMQKLWQLIQGMTGEESAVQHGVSKRMALVIGARRHLECGHGKHIMDTIQSHPTQAALGGSVGNLQRIRAFLRIRLRDYGSLDFDSVDARRQPPVDTTWQQIYFCLRTGYYEEAREIAQSSRSSQQQFAPLLTEWITTGGTVAAQTAATASEECEKLLRMGDRFGQTTYDKKKLLLYTIISGSRRQIDRIMRDFSTLFNTIEDFLWFKLSCVRDVAGGSSSMIVNDGLVPYSLDDLQAYLNKFEPSYYTKNGKDPLVYPYVLLLSIQLLPAIMHMSNEAGDEGYNIDAVHVAISLVDHSILSEGSGTGRKLSVMDANAEASSMIRQYGSMYLHHGDLQMTLEYYAQAAIAVGGGQQAWSGRSNVDQQRQRNLMLKQLLTEILSQEDGIHFLLGARGSGEEGELGRFLPDIKLRQQFLIEAAHQFQEAGLYDKSIELQKRVGAFSSALETINKCLSEAICSLVRGRPDGESRTEGLVLSGNDILNSYKYHPDVSAQERHLVMEQETILRELEAILSIHKLARLNKHLDAIREVAKLPFLHLDPRQPDTTSDEFQKASSYFQTCVPDLLKVALTCLDNVADTDGSIRGMRSKIAGFLASNTQRNWPRDLYEKIARSF
Protein: Cilia- and flagella-associated protein 161 (F6RJC2)
Organism: Bos taurus (Bovine)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37327785}.
Interaction partners:
- EF-hand domain-containing family member C2
- Piercer of microtubule wall 2 protein
- Leucine-rich repeat-containing protein 46
- Low density lipoprotein receptor class A domain containing 1
- Actin-related protein T2
- BET1-like protein
- Epithelial cell transforming 2 like.
- Zinc finger protein 474
- Cilia and flagella associated protein 221.
- Cilia- and flagella-associated protein 52
Sequence:
MAQNLYGPRVRIGNWNEDVYLEEEIMKDFLAKRDKGQLLIQRNRRLKENLLRPMQLSVSEDGYIHYGDKVMLVSPDHPETEADLFLPGDLSLCMTPDEIKAHLSNELEVPCGLSAAQTKIPVGRNTFTILCAAGEVIGQVLRYGQNFRLGITGGFDDRMLYLSSDHRTLLKSSKRSWLQEVFLTHEDSYLNCWQAAFPHPQLRLEYEGSPVPANTKILITHCHTNRGLVAHRHLFLRTYFGQEAEVAAHTYLDSHRVEKPKNHWMLVTGAPRKDLSTMLDLPKPPAEDTRALEQEREQVSDPGARSTPDARGCVPQCTLPM
Protein: Histone-lysine N-methyltransferase ATXR6 (EC 2.1.1.369) (Protein SET DOMAIN GROUP 34) (Trithorax-related protein 6) (TRX-related protein 6) (Q9FNE9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1). Has higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. May act as a positive regulator of the G1-S transition. Influences which sets of rRNA gene variants are expressed or silenced. Up-regulated by E2FB.
Subcellular location: Nucleus {ECO:0000269|PubMed:16771839}.
Interaction partners:
- Histone H3.1
- Histone H3.3
- Histone H3-like 4
- Histone H3-like 5
- Histone H3-like 1
- Histone H3-like 2
- Histone H3-like 3
- Histone H3-like centromeric protein CENH3
- Histone-lysine N-methyltransferase ASHH1
- Histone-lysine N-methyltransferase ASHR3
Sequence:
MVAVRRRRTQASNPRSEPPQHMSDHDSDSDWDTVCEECSSGKQPAKLLLCDKCDKGFHLFCLRPILVSVPKGSWFCPSCSKHQIPKSFPLIQTKIIDFFRIKRSPDSSQISSSSDSIGKKRKKTSLVMSKKKRRLLPYNPSNDPQRRLEQMASLATALRASNTKFSNELTYVSGKAPRSANQAAFEKGGMQVLSKEGVETLALCKKMMDLGECPPLMVVFDPYEGFTVEADRFIKDWTIITEYVGDVDYLSNREDDYDGDSMMTLLHASDPSQCLVICPDRRSNIARFISGINNHSPEGRKKQNLKCVRFNINGEARVLLVANRDISKGERLYYDYNGYEHEYPTEHFV
Protein: Defective chorion protein, FC177 isoform (P18171)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for proper assembly of the eggshell.
Subcellular location: Secreted {ECO:0000269|PubMed:3378704}.
Interaction partners:
- Vitelline membrane protein Vm32E
- Vitelline membrane protein Vm26Aa
- Vitelline membrane protein Vm26Ab
- IP19021p
- Vitelline membrane protein Vm34Ca
- Protein palisade
- Chorion protein b at 7F, isoform A
- Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein
- Follicle cell protein 3C-1
- Chorion protein c at 7F
Sequence:
MRLFSLLPLLALLVVQAAGQSEVTSDDPATDAGSTTNSTTDTKPRIPSQDEILGQMPSINPIRTGNPQMDAFYMMFPALGSLLKWGSLFPAYSILGAIPDNLQPTAAASKVVLVLADDATAKTRVARQNPPPNPLGQLMNWPALPQDFQLPSMDLGPQVGSFLAQLPAMPTVPGLLGAAAPVPAPAPAPAAAPPPAPAPAADPPAAPVPDAPQPAILGQAALQNAFTFFNPANFDASSLLGQSVPTFAPPNLDFVAQMQRQFFPGMTPAQPAAAGTDAQASDISEVRVRPEDPYSQEAQMKIKSALEMEQERQQQAQVKDQEQVPLLWFRMPTTQNQDATEEKTLEDLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSAAAQNGDSPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRARNSGINTQKANALKRQAKSQDQTLSKEDIVQIMAYAYRMANEQMESEKGKQDKVYAAYRTEQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMVQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQHDQQMAQQMAQQGLMMTEQRQRQWSEDQAKIQQAQQMAQQTPMMMPQMQQRQWTEDPQMVQQMQQRQWAEDQTRMQMAQQNPMMQQQRQMAENPQMMQQRQWSEEQTKIEQAQQMAQQNQMMMQQMQQRQWSEDQAQIQQQQRQMMQQTPMMMKERQWAEENPQSVQQQGPMMMQQQMPSMMQREVEDEDNKAEDDLVGEAGPQMPENEGTARHKVDALGVGGNKRKKSKSKSAPPTVINYYYAAPQRPVVQSYGTSYGGGGYGSNAYGVPRPVNSYQSQGYRAAVGNDEVDEMLRQHQTMARTINPKQPGEVGGSESQKSNSNPPTTLTPAPQEQPQEHRVHKRLAHFHRFGREAGLNATTSKGCGCGRLDCLCGRSCRCGRRGLESRVVSSRTSGTCQCKASHRNKRSVEYGTLETIDEGSLNELRREYKLGLKEITLSPDEDPAEALMRYNAASIREALERASMEPLEIGGDQYEEDAQQEPMEEEQLQHDPNTEPQYNHKDFVRLTTSTASPITSTTEAATPTGSDSTSEATVTPEVTTTTSTSTTTTTESTKDEGLDMQQDSQAEAESSHVTKSISKQEAEIHQLHSIVEELKNEILKLNLRCSTIISNNVAKEPVTEKNPPVVEEPSKQEDKPKVEEKVIAEEQAPVEQEEELEEDEDSTSISTTTETPSPSGSYSTKPGLSLGSPRVDEQSGSSNKLDYDDDNNWQRILANRGYDTDYLTKSHERQFAQGQNLEMPKNCNYDGNGSQEYGPYPEFQADEPSTDTEGKAKRALSVKQQAQLLNAALNDSGSDSSDGTTTTTTPSPYAMRGKFVRRRSTARRVPIPKIGKASDEVWVRSPRQAKMPQRPKKSMSKPKKQSSQVTTQATVSSTKLDSLVDVLKDLVRLQIQKEKKSSLLRTQSNNLSKTKPKSIKPVKVIKRKRLRRRQHKSIATTIRSPIQTKA
Protein: Electron transfer flavoprotein subunit beta (Beta-ETF) (Q9DCW4)
Organism: Mus musculus (Mouse)
Function: Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (By similarity). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:P38117}.
Interaction partners:
- Electron transfer flavoprotein subunit alpha, mitochondrial
- Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Short-chain specific acyl-CoA dehydrogenase, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Electron transfer flavoprotein beta subunit lysine methyltransferase
- NADPH-dependent diflavin oxidoreductase 1
- Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Sequence:
MAELRALVAVKRVIDFAVKIRVKPDKSGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEIIAVSCGPSQCQETIRTALAMGADRGIHVEIPGAQAESLGPLQVARVLAKLAEKEKVDLLFLGKQAIDDDCNQTGQMTAGLLDWPQGTFASQVTLEGDKVKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVVKAGDLGVDLTSKVSVISVEEPPQRSAGVKVETTEDLVAKLKEVGRI
Protein: Cathepsin K (Q5QP40)
Organism: Homo sapiens (Human)
Subcellular location: Lysosome {ECO:0000256|ARBA:ARBA00004371}.
Interaction partners:
Sequence:
MHKENEEIYNVSENRKHCPIFPCPLLTRSGKVPEFRHEREERLEEMIRRQNLDGNLSFVMWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Protein: Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase) (O94354)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable argininosuccinate lyase
- Ornithine carbamoyltransferase, mitochondrial
- Argininosuccinate lyase
- Carbamoyl phosphate synthase arginine-specific large chain, mitochondrial
- Protein arg11
- Multifunctional protein ura1
- Carbamoyl phosphate synthase arginine-specific small chain
- Peptidase M20 domain-containing protein C757.05c
- Probable asparagine synthetase
- Adenylosuccinate synthetase
Sequence:
MPQEVKRCVLAYSGGLDTSCILAWLIEEGWEVICYMANVGQEEDWDAAREKALKVGAKKVYVEDLREEFINDTVIPAAQANAIYENVYLLGTSLARPIIARRQIQIAEKENCIAVSHGCTGKGNDQVRFELAYYALKPDVQVIAPWRLPVFFERFAGRKDLLEYAAAKGIPVTQTTKKPWSMDENIVHCSYEAGILEDPSMTPPKDMWKLTVDPKDAPDEVEELSIHFEKGAPTKLECKDGTFSGVVSIFYQLNAIARRNGVGRIDIVENRFSGLKSRGCYETPGLTILRTAHMDLEGLTMEREVRALRDQFVTFNLAKILYNGQFFSPCTRMLLAANNVSQEVVNGVVKLSVYKGNVTVLGRKSDTAHLYDEKLSSMDELGGFDPTWTSGFIQIESMRLRNSDEGKHWM
Protein: E3 ubiquitin-protein ligase MBR2 (EC 2.3.2.27) (HAL3-interacting protein 1 homolog) (AtHIP1) (MED25-binding RING-H2 protein 2) (RING-H2 finger MBR2) (RING-type E3 ubiquitin transferase MBR2) (O49500)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase that functions as regulator of MED25 stability by targeting MED25 for degradation in a RING-H2-dependent way. Proteasome-dependent degradation of MED25 seems to activate its function as positive regulator of FLOWERING LOCUS T (FT) and is important to induce the expression of FT and consequently to promote flowering. May function downstream of HAL3 and be required for HAL3-regulated plant growth. Activation of MBR2 by HAL3 may lead to the degradation of cell cycle suppressors, resulting in enhancement of cell division and plant growth.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 25
- Protein WVD2-like 4
- Protein WVD2-like 7
- TPR repeat-containing thioredoxin TDX
- Protein WVD2-like 3
- ARM repeat superfamily protein
- Fes1C
- Fes1B
- Mediator of RNA polymerase II transcription subunit 23
Sequence:
MQGPRSTGDSSTGINYADGEPICSTNSETTSNNILNPVDVQFPNNTTGSGRPTYASSSSHVVQNHNWWSFGESSSRLGPSDHLNSNGSKTDRQLLSDGYGFEEGQSGMLLPGESFLRGSSSSHMLSHVNLGKDMDIGSGLQTSGVVIRHNNCETSLGSSSQTAEERSSGPGSSLGGLGSSCKRKALEGAPSHSFPGESHGCFFQTENGAWNEGLAQYDASSSLSLSMPSQNSPNVNNQSGLPEPRFGLGGGRAVTASAFPSTRSTETISRPGRRLNPGQPPESVAFSFTQSGSSVRQQQQLPATSPFVDPLDARAIPVTGSSSSGDGQPSMIHLPALTRNIHQFAWSASSSSRANSMPEEGLSPWDAPRINSEQPVFTTPANETRNPVQDQFCWSFTRGNPSTSGDSPFVPRAGSSSGIHGLQPNPTWVTPHNQSRISEVAPWSLFPSIESESATHGASLPLLPTGPSVSSNEAAAPSGSSSRSHRSRQRRSGLLLERQNDHLHLRHLGRSLAADNDGRNRLISEIRQVLSAMRRGENLRFEDYMVFDPLIYQGMAEMHDRHRDMRLDVDNMSYEELLALGERIGDVSTGLSEEVILKVMKQHKHTSSAAGSHQDMEPCCVCQEEYAEGDDLGTLGCGHEFHTACVKQWLMLKNLCPICKTVALST
Protein: 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) (Q9ZGA0)
Organism: Pseudomonas aeruginosa
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MHFDSVTGWVRGVRHCPSPNFNLRPQGDAVSLLVIHNISLPPGQFGTGKVQAFFQNRLDPNEHPYFEEIRHLTVSAHFLIERDGAITQFVSCHDRAWHAGVSCFDGREACNDFSLGIELEGTDTEPYTDAQYTALAGLTRLLRAAFPGITPERIQGHCDIAPERKTDPGEAFDWSRYRAGLTDSKEET
Protein: Endothelin-converting enzyme (AFU_orthologue AFUA_3G12420) (C8VIN1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MGDRITLPDSPMSDDGEERTLLLQDHFEHQLEKCSALSESEYLEESSKLQRSGRSRCWPSRSWLSTSCYATLWTGSAILLMTAGYLASPMLKEPSNSDGPHTEAPTICQTPECVNAASDILRNLDPNYANIDPCTDFDQYVCGGWRNQHDMRSDQGSIFAGTYMEEASQTRLRHLLESTGPSDPADSKIFEKLKAGYNACFDEDAVRNRGNEPLVKLLNDFEKIYSLDSAMGGTEAGLTDSVLYLYKSGVPALVLPSVSPDDRDPDNVVIFLTPPRKIGLPAREYYNDTQTVSDYTAVVETVLGEFVGSKKGKQFSKDVVAFESALADVTPTTQVQEDVTQYYNPRSIEETESLLPQILISDIISDLAPSDYETNRIIVGSPSYMKSLSKILADTSRETIQFFFKWKIIQAYSEHVESAEIEPLREFNNVIAGKDPQAKMDRWRKCITTVDEDLGWILSRFYILDAFPEESKRLGDQIVSDIKERFVFTLDQTNWMSSEVRKLGIQKVGNIVQKIGYPTKSPNVMDPADVEKYYQSLSISNDTYFENGLAVSRFVVEKEWSELAPTVNAYYNPPGNEIVFPAGIMQPPVFYGKGAPLYLSYGAFGAVSGHELSHAFDSTGRHYDETGNYTDWWDEKTVKAFEDRAQCFIDQYSNFTVHGKDSELHVNGRLTLGENIADAGGLTAAYHAWKKRDEAHADPILPGLSSFSKEQVFFISYANWWCSKTTPEKAQEAIYNDPHAPKPARIIGTMANSLEFKEAFNCPNKQPTCKLW
Protein: Ski oncogene (Proto-oncogene c-Ski) (P49140)
Organism: Gallus gallus (Chicken)
Function: May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. May function in TGF-beta signaling (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Mothers against decapentaplegic homolog.
- Mothers against decapentaplegic homolog
- Mothers against decapentaplegic homolog 3
- Methyl-CpG binding protein 2.
Sequence:
METVSRSSFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEMYKKDNGKDPAEPVLHLPPIQPPPVMPGPFFMPSDRSTERCETILEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGTYPPHCKKEFSSTIELELTEKSFKVYHECFGKCKGLLVPELYSNPSAACIQCLDCRLMYPPHKFVVHSHKSLENRTCHWGFDSANWRSYILLSQDYTGKEEKARLGQLLDEMKEKFDYNNKYKRKAPRNRESPRVQLRRTKMFKTMLWDPAGGSAVLQRQPDGNEVPSDPPASKKTKIDDSASQSPASTEKEKQSSWLRSLSSSSNKSIGCVHPRQRLSAFRPWSPAVSANEKELSTHLPALIRDSSFYSYKSFENAVAPNVALAPPAQQKVVSNPPCATVVSRSSEPPSSAAQPRKRKHAAETPAVPEPVATVTAPEEDKESEAEIEVETREEFTSSLSSLSSPSFTSSSSAKDMSSPGMQAPVPVNSSYEVAAHSDSHSSGLEAELEHLRQALDSGLDTKEAKEKFLHEVVKMRVKQEEKLNAALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRIRLKRELEQARQIRVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLMHEREAREHLEKVVKELQEQLWPKSSSQSSSENTTSNMEN
Protein: SD10857p (Q8T994)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAETLAEEKPKEKSKASRRKDKKDKTNQIVKIVMRHLPPTMTEAQFLDQVGPLPENDSYYYCKADWSLGQEATCRAYIDMSSKDIGEVVQFRDRFDGYVFVDHKGVEYMAIVEYAPFQCFLKNKARNDDSKVNTIESEPHYQEFIKRLAQEREEASRMGDVKIDFNFERRTEEKVKSTPLLQYLANKKEKRREEARRRNEEKRKQREEQKLLRLAAQSDASKLKEAEGGGGGGDTKKPAKKDVKDPQSSGSQANDAKASRSKRRTERDQRRREEHEQRKLVKRDKKKDDGQGKQDKQDKQDKGKSSSGKQNKNSKSMDIVILKKANKPESNESLDVPSTSNAAEASKEKPATENTETPEAAVKVFTPAARGGRKEKRTGADKQPAGSAHETAEEAIKAAQFRASPNPPRAAPASNSDNRLLLLNKSCTHGWSRPVSRTRPPSPFVCSTFD
Protein: Tachykinin-related peptide 3 (TKRP-3) (P86559)
Organism: Acrosternum hilare (Green stink bug) (Nezara hilaris)
Subcellular location: Secreted {ECO:0000269|PubMed:19084564, ECO:0000305}.
Interaction partners:
Sequence:
GPSSGFFGMR