wanglab/gogpt-training-data huggingface dataset:
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q580P4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MQVQRTTKEVLHKAVAAAVPVLFMTLMRCGMAQTVTEPSSDKVTNLCTEAKYTAHLADHIVAAAEEPEREISDMQIYAEAWNLLAASTNQTDKRAATYALATYMSTAAAKAKQLQNGKYKAAVLAATYLQRRSALTRTLQAMRVKGQSGAGQVTNRQGVISSCSHKETPTLSDEGDCGRQGSDANHPESIAVNLRTATHLKLLDSSRLRPLALNHLAEVEGTAPPAKTEVQAEGCKAVISIGYYAKFTASTKESDDNSEVKAIKIFAGDNASTNCALLHNAERKSEKDNDLLINKICNYINKPDPQIITISNLTPAMLANTSTVQMAFKSFVHAATGKAPSDGEIENQLKSLYGGDEVTFTNDFIKILWTKNVTYHTGSGFVTETFLDAAKNENAHKVLIYLKGQRAAAQAKQPRTNESEINGPVCGGEGQEECKLDEKKDPEKPNGTQMRKWPKALQWMITRQGGNCKTIQQEDCKEDCTWDEGACDGAVGISASMNISLFMAFLLLA
Protein: KLF transcription factor 5 (F1LSL7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Steroid hormone receptor ERR2
- F-box/WD repeat-containing protein 7
- CCAAT/enhancer-binding protein beta
- CCAAT/enhancer-binding protein delta
- E3 ubiquitin-protein ligase
- Estrogen receptor beta
- Transcription factor Jun
- Retinoic acid receptor, alpha
- Nuclear factor NF-kappa-B p105 subunit
- Cellular tumor antigen p53
Sequence:
MPTRVLTMSARLGPVPQPPAAQDEPVFAQLKPVLGAANPVRDAALFPGDDLKHAHHHPPAPPPAAGPRLPSEELVQTRCEMEKYLTPQLPPVPIISEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTQIKTEPVTIFSHQSESTAPPPPAPTQALPEFTSIFSSHQTTAPEVNNIFIKQELPIPDLHLSVPSQQGHLYQLLNTPDLDMPSSTNQTAVMDTLNVSMAGLNSHPSAVPQTSMKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPATLPVNSPNIQPVRYNRRSNPDLEKRRIHFCDYDGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCVVCNRSFSRSDHLALHMKRHQN
Protein: Peptidoglycan-recognition protein LA (Q95T64)
Organism: Drosophila melanogaster (Fruit fly)
Function: Peptidoglycan-recognition protein probably involved in innate immunity by binding to peptidoglycans (PGN) of bacteria and activating the immune response.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Peptidoglycan-recognition protein LD
- Peptidoglycan-recognition protein LC
- Peptidoglycan recognition protein SB2, isoform B
Sequence:
MFEENNSPTTDNSLWTLQGRQRASPAQRLHNLTSAGSSTSSSGLPLPQNIFTNPAIQPSSVINLNHSTDVVIGPMTQYQGPVSIYYMDYMEAHAMQTAAGINSNNANGNGNANRSRDKSPSRRVTRNTILLITLILLVLATGLIVLYVELNRPKPELPSNKAIYFGNNYDHQTFPNLGNGHLVVDREQWGASKNSHGLTIPLKRPIPYVLITHIGVQSLPCDNIYKCSIKMRTIQDSAIAEKGLPDIQSNFYVSEEGNIYVGRGWDWANTYANQTLAITFMGDYGRFKPGPKQLEGVQFLLAHAVANRNIDVDYKLVAQNQTKVTRSPGAYVYQEIRNWPHFYGCGMDEAPACGIELGMKTESWDAKQ
Protein: Activity-regulated cytoskeleton associated protein 1 (dArc1) (Q7K1U0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer from motorneurons to muscles. Arc1 protein is released from motorneurons in extracellular vesicles that mediate the transfer of Arc1 mRNA into muscle cells, where Arc1 mRNA can undergo activity-dependent translation. Intercellular transfer od Arc1 mRNA is required for synaptic plasticity at the neuromuscular junction. May play a role in energy balance: required for regulation of body fat by a specific population of brain neurons, named E347, that are necessary and sufficient for proper body fat storage.
Subcellular location: Extracellular vesicle membrane {ECO:0000269|PubMed:29328915}. Synapse {ECO:0000269|PubMed:29328915}. Note=Forms virion-like extracellular vesicles that are released from neurons (PubMed:29328915). Present at pre- and postsynaptic sites of the neuromuscular junction (PubMed:29328915). {ECO:0000269|PubMed:29328915}.
Interaction partners:
- Activity-regulated cytoskeleton associated protein 2
Sequence:
MAQLTQMTNEQLRELIEAVRAAAVGAAGSAAAAGGADASRGKGNFSACTHSFGGTRDHDVVEEFIGNIETYKDVEGISDENALKGISLLFYGMASTWWQGVRKEATTWKEAIALIREHFSPTKPAYQIYMEFFQNKQDDHDPIDTFVIQKRALLAQLPSGRHDEETELDLLFGLLNIKYRKHISRHSVHTFKDLLEQGRIIEHNNQEDEEQLATAKNTRGSKRTTRCTYCSFRGHTFDNCRKRQKDRQEEQHEE
Protein: Iron-regulated transcriptional activator AFT2 (Activator of iron transcription protein 2) (Q08957)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcription factor required for iron homeostasis and resistance to oxidative stress. With RCS1, activates the gene expression in response to low-iron conditions, also called iron regulon.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Monothiol glutaredoxin-3
- BolA-like protein 2
- Plasma membrane iron permease
- Iron-regulated transcriptional activator AFT1
- mRNA decay factor CTH2
- AP-1-like transcription factor YAP5
- Iron transport multicopper oxidase FET3
- Iron transporter SMF3
- Mitochondrial RNA-splicing protein MRS4
- Protein CCC1
Sequence:
MKAKSMKSIISVPISVSKTGKMKLTASPDNLASMMSKDQNKLIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVRSKVGLNPKSKGSSSRSHACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPLVTPIISCDCGLTKEIEAFNNIFLPLSNPPLTSKKNLLKTNKNSVSKIKSRQMDNSKPRPRLKTKLDADLHDTGFLDNFKTRNSCVKIEKEDSLTNLNEIDFTNMFCNDNFIQNYNQGLMELLTEPTPGPSSSSCILPSTPTRPLSQSKMDIALSESTTSSPNFMETDAPYGDEIIKVSKDTKSNAPTADTDIATNLGKERNENFGMLNYNYEALLHFNDEHFNELNSIDPALISKY
Protein: Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164) (Q3USS3)
Organism: Mus musculus (Mouse)
Function: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:P0DL09}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:P0DL09}.
Interaction partners:
- Coiled-coil domain-containing protein 39
- Dynein regulatory complex subunit 4
- Dynein regulatory complex subunit 2
- Dynein axonemal assembly factor 19
- Dynein regulatory complex subunit 7
- Dynein axonemal intermediate chain 2
- Dynein axonemal intermediate chain 1
- Dynein regulatory complex subunit 3
- Dynein axonemal heavy chain 2
- Radial spoke head protein 9 homolog
Sequence:
MNPSGTIGVLEQNGEEHLATPILGPSVHSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVAADVREIHRRVEEEETKRQRLEKLENEVKTSQDKFDEITAKWEEGRRKRIPQELWEMLNSQQVHCAELIEDKNKLANELQQELKIKDDQYVKDLKKQSEDITLILERMEEQVKNVMKNFRQELIHIEKAFESERQELLSSNKKKWERALQAHNAKELEYLTNRMKKVEDYEKQLNKQRVWDCEEYNTIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDVVNNLRTKYTKQIRQFQDDNQSLTSDYKRLVTQFKDLQKALRHFIIIDEEKFREIWLMNEAEAKELAQRAFDVDRIIHSQHLGLPWNMPDLWFLNNVGPISLQQQKSVTQILEELLLQTEDEATEAAMSEDEDYMDLPNQISAKTTTKVLMLLCDESGFLIESKLLSLLHPLEKSECYLLRLDAIFSALAIEDEDDLYKLVNFFLRYRAHRLSSAQASSSIHSNVERTSLMSALERLSLMSQTDKGSMVSKSDQEPTEQEDEQEGDNASLSSRELEEQEDLSSPRFIHPNDVLKILEAFVTGLKKPKDAQPVLKLKKETRDNSKDTEYWESLAAVIPFFKQNLWDALYKALEKYYLVLTERAKLLMENESLEQQNAEMQSLLQQYLQAKVNTELQIPPTQGFRMPSK
Protein: ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit) (P0ABA6)
Organism: Escherichia coli (strain K12)
Function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:16079137}; Peripheral membrane protein {ECO:0000269|PubMed:16079137}.
Interaction partners:
- ATP synthase subunit beta
- ATP synthase subunit a
- ATP synthase epsilon chain
- ATP synthase subunit c
- ATP synthase subunit alpha
- ATP synthase subunit delta
- ATP synthase subunit b
- NADH-quinone oxidoreductase subunit C/D
- Elongation factor Ts
- Small ribosomal subunit protein uS3
Sequence:
MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
Protein: F-box only protein (E2JEI9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369085}.
Interaction partners:
- S-phase kinase-associated protein 1
- S-phase kinase-associated protein 1
- Elongin-C
- Elongin-C
- RING-box protein 2
- E3 ubiquitin-protein ligase RBX1
- E3 ubiquitin-protein ligase RBX1
- RING-box protein 2
- Cullin family profile domain-containing protein
- Cullin-1
Sequence:
MALREDSSEDELQGQFSLLSATSFEVTDESEDTHGRSETGILDLSDEVFILILRRLDPTSLLRVGSTCRTLFRVCSCNSLWTKHFQTSFGVPFATAACSISAKSAFRLVFMWRTLFRNLHCNRSLQEKLFAEIPFPPHKYWVQWLVLEETVPLPSVRLPCTDIESLWGIEKEVLEGKVQEKDEDEGRMLKFEWKELYALALEHHGSIAKVFQHVLNQQSNDHCELEAMFSQYSQCRFQWLFTYWLFRQPAPFDRQLRAIYLQWQKHSKRKVVSWGGTLCDIRYLASLHHITSDYWRGKLAQGDETVGIQTVENYFSMCKSLVAWILGRDWGRLKSKKVYEDTLEGVYLLLRREMQETLVEHERFWQVAKVQMTRVCTLEETAVNYVNWKMIETLPYYKLYLVSGNMVYLDHVQGFLHRKRLVHDWFFMKENTWVRQLLPGDLYPLLEFDTKISQDSLHGDSMPAQLSRVMWLYLHSGQTLYLEAVKGLVLQCAQASLGHFCSLSPGASIQPHVS
Protein: Diester hydrolase, putative (P71651)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MSTTSARPERPKLRALTGRVGGQALGGLLGLPRATTRYTVGHVRVPMRDGVQLVADHYAPATSQPVGTLLVRGPYGRRFPFSLVFARIYAARGYHVVLQSVRGTFGSGGVFEPMVNEAADGADTVAWLREQPWFTGRFGTIGLPYLGFTQWALLHDPPPELAAAVITVGPHDFRASVWGTGSFTVNDFLGWSDLVSHQEDPGRIRAGIRQLTAPRRVARTAATLPLGESARTLLGTGAPWFESWVEHTDRDDPFWDRLRFPAALDRVQVPVLLVGGWQDIFLRQTLQQYRHLRDRGVHVALTVGPWTHTQMLTKGLATGARESLDWLDAHLGRAPALRPSPVRVFVTGQGWRHLPDWPPATTERAWYLQPGGRLGESAPASGTPPATFRYHPADPTPTTGGPLLSSNGGYRDDSRLATRADVLCFTGAPLTHDLCVHGNPVVELVHSSDNPYVDVFVRVSEVDAKGRSRNVSDGYRRLGDAPELVRVELDAIAHRFRADSRIRVLIAGSWFPRYARNLGTPEPILTGRQLKPATHAVHFGRSRLLLPVG
Protein: CSD domain-containing protein (Q57UC8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFRLAGSRLAVSITATLLEKKRGNAAEPIPTNIAASASMEVAPRRVGTVTSFMHRRGYGFITALQLSSSDSPDTQCLASAELEAAVRENAENFFFPRSSLDGGFYVSQGQTVTFDVLPSPQVNEQVEKEHREATEDIEASGDPPKSLPVARHIRLCDLDTGKERPVTPVMLHGCVQSWDTITGSGCIAELDLAGNLHDDAPCFNFSLEDLDVVNISDLHQGCFVRFCIERGDRNAARRVIIDRSTGKRHAPLQQWRSSQGASRALGFAADSKPAAARYYGTVRELVDGRFGFIVLEETGESIFFHMSNVDQDDQNASIKVGDTVSFILRGVSQGKHAGKRTCLKIRRCSPQPSLASRNHNSGKGTNHLSDDDDDDEFNLLE
Protein: Aspartate aminotransferase (EC 2.6.1.1) (Q9VQ61)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSQICKRGLLISNRLAPAALRCKSTWFSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAEKRVVSRSLDKEYATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKFWQGNREIYIPSPSWGNHVAIFEHAGLPVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACAHNPTGVDPTLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFAKNMGLYGERAGAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRIIDVRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSKNVEYLAESIHKVTK
Protein: Plastin-2 (65 kDa macrophage protein) (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (pp65) (Q61233)
Organism: Mus musculus (Mouse)
Function: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14756805}. Cell projection {ECO:0000250}. Cell junction {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000269|PubMed:14756805}; Peripheral membrane protein {ECO:0000269|PubMed:14756805}; Cytoplasmic side {ECO:0000269|PubMed:14756805}. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28. Relocalizes to actin-rich cell projections upon serine phosphorylation (By similarity). Associated with the actin cytoskeleton at membrane ruffles. {ECO:0000250|UniProtKB:P13796}.
Interaction partners:
- Actin, cytoplasmic 1
- NF-kappa-B inhibitor alpha
- Tumor necrosis factor
- F-actin-capping protein subunit beta
- Interleukin-1 beta
- Glyceraldehyde-3-phosphate dehydrogenase
- Hematopoietic lineage cell-specific protein
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Interleukin-6
- Allograft inflammatory factor 1
Sequence:
MARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGKISFDEFIKVFHGLKSTEVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCTKITNFSTDIKDSKAYYHLLEQVAPKGDEEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNKYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDIGGGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV
Protein: Centrosomal protein 135kDa, isoform C (M9PCK8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}.
Interaction partners:
Sequence:
MNINDGDFKDLRCKLDIMGFTQTLPVLAIPLVQAVFGDLIKTTECLRDTKKKVAELLEEKTCWELGVEPYKCDNSRLLAECNELHLQFLRDREDYELRLCESERKIRNLELDKQHLQSHNDGLQRQLDALLTKQMVSSVTNKKATAGIGRQTKKPFITTVRSGIAMPTTLGTSSSALKCTKCNAGVFQKTTTTTKDGVTVTQTSGQEELDKMQNDLTAAGEQLEFFKRKVEARNREIRRLNDMLAGGRPLAALAKDCCYKDVGALSQDIDLLQREKSDLMMQVREFQDKMHDAMQRALSSEEDKIKLQTQLEELKEAALQVEQQANAEIDAKESELRQLQLELKKKGKDHRLTGGFASNQSDKHNLNERLNLLTRREEELQATNEKHKKKIQKMQAKILELQKELKDQNKHSNVTLDEEKIRLSSERDFFQKEYLRLMSKTGSESEIAFLHAQIKSKDEELKALRSELFHGGKQQFSPQKSVQYETLPPPTASSITSTVTSNTSDCVQAAIARVERERDCARTELERVRCERDTLREKQLSTVQLHADELQALRLRNEELNDRLRQMERDNRELNSARLPTETNLVLLKEDLLQMRQRVASMQTEIDQLKTENDQITMLNDQNERIIADYQSKLLVAERQRQSADVRASTLDSSRESNRSEVTQLRMDLGALRQTYISLEHEKDTLLHQLDTKTERVYKLEYELKDCKEKRNALEQNVKDLEDQLRKLANRNRQRDSELTETSTESKTLRQQIVALKASRDEAIAENRRLMDKLSDAQVEARTLQKKLTDSELQVANMKQQLHKYVQEVKKAEDLLIQKEKERDDMLDQYHCLTQGQATLEGNNQSLECEAVEFRRQICELECEVHSLKEQLQLRQCALHDMEVQLTAARASVRCLERELENARDDIRVQKVDLEARKELCDKLDVERSKLNAELNDVNEIRKKVSFSSGPDHFPYLYPS
Protein: Zinc finger protein 689 (Q8BKK5)
Organism: Mus musculus (Mouse)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MAPPSAPLLLRAVGEAGPTRKRGRRPRALKFVDVAVYFSSEEWGCLQPAQRTLYRDVMRETYGLLGALGCAGPKPALISWLERNTDDWEPAALDPQEYRRWVTFQRKTRSKQKTEEKDVFPPKEAPRKGKRGRKPSKPRLIPRQTSGGPICPDCGCTFPDHLALESHKCAQNLKKPYPCPDCGRRFSYPSLLVSHRRAHSGECPYVCDQCGKRFSQRKNLSQHQVIHTGEKPYHCPDCGRCFRRSRSLANHRTTHTGEKPHQCPSCGRRFAYPSLLAIHQRTHTGEKPYTCLECSRRFRQRTALVIHQRIHTGEKPYPCPDCERRFSSSSRLVSHRRVHSGERPYACENCEARFSQRSTLLQHQLLHTGEKPYPCPDCGRAFRRSGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASHRRVHSGERPYACDLCSKRFAQWSHLSQHQLLHTGEKPFPCLECGRCFRQRWSLAVHKCCPNTPNGSPRPLIGGPSQRSSAL
Protein: T-box transcription factor TBX15 (T-box protein 15) (MmTBx8) (T-box transcription factor TBX14) (T-box protein 14) (O70306)
Organism: Mus musculus (Mouse)
Function: Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- T-box transcription factor TBX18
- Myc box-dependent-interacting protein 1
- Transducin-like enhancer protein 3
- ETS translocation variant 3
- Forkhead box protein O3
- Myc proto-oncogene protein
- Histone deacetylase 5
- Probable ATP-dependent RNA helicase DDX20
- Max dimerization protein 1
- Histone deacetylase 2
Sequence:
MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTASATQPSETFMPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSMHMISPSTNNQQATNTCDGRQYGAVPGSASQMSVHMV
Protein: Cytochrome P450 2G1 (EC 1.14.14.1) (CYPIIG1) (Cytochrome P450 olfactive) (Cytochrome P450-OLF1) (P10610)
Organism: Rattus norvegicus (Rat)
Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. This isozyme seems to be implicated in olfaction.
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Interaction partners:
Sequence:
MALGGAFSIFMTLCLSCLLILIAWKRTSRGGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVEMSMPWAQLYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNPRDFIDCFLIKMYQDKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSLRSLVPPADIDIAHKISGFGNIPPTYELCFMAR
Protein: U-box domain-containing protein (Q57XK6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MATVKKLLERLNDGKVLTTEEMIYWADKSDETHSQTFFGKNIEDARHCVRCVADTLIKKYMNNPDVSELPIEKKTRACLIVSNFALYKPVRNCIFDLLDKLEAVFEESIKADAALPFNPELGRMTEHVAVLLMRVTGYKLKAANVFEFTDGNVQFSVQLMLAVLLKEPPYEPALRCNCISIILGFTQPQAYFNDAAGVEDASCQDFTEKIDGILKLMLRLNAVQVFDDVLSEQLDNVKEVTPLLHVAVCSAMRCVMNIFRFSSTGGTQWRQHILLSTTHLDHSVTVYLQLQCISLQKSLSLPQPTASVEMLRGMSLGYKFASLCTFGMGCHTRETRLFFPYLHDMLQLPVKSILGSPALANAVMRVYVDMFHLIANIDALGGDEGLPTGDMFPQLQSAELVKSVTGFLKREVAPCGLAFIQAWHNALKTVEPDTLVERGTPTFLELEKIFSEVESAVEKQSAPRPPPPPQPSAPAPVPASTPEQAPVDLCFVGRSHLADIPPIHRKAADQKISIDNAAVPVAPSNRTKPVDRNSAIGIDERMLCALTGNVMKKPVVSPHGHTFDHEAILAWLEQNGSVCPVTGKPLVATELRPNKEITALIMRQTIAQSMTAPNQENEVDIYDF
Protein: Chaperone protein DNAJ, putative (Q57Y63)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWRVALRRPRVAMPCGCIGHIYRRGSGVPYGSVPADIESSRHSRKPREEDVLKNISGRSGSDQANEETPAYEAEGYDPWRVLGLKPGASTHMVRLRYHELMREVHPDLEPNRVGDISRLNQINKAYEIITKSPTIDRRYRNLVSDTQYFYYKFLPEWMARNVDEMPRYWSWVRWRTPGAFQVFLLCCGCYMVGRFYAAFPVLTTAFLLSLSFDILFHTMTAPATCSMLFLYAIMSSQSYDMAWLTSPKSFLKRELSY
Protein: Forkhead box O3 (F1NNE8)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
- Deacetylase sirtuin-type domain-containing protein.
- Cyclin-dependent kinase 2
- Non-specific serine/threonine protein kinase.
- non-specific serine/threonine protein kinase
- RAC-alpha serine/threonine-protein kinase
- Mothers against decapentaplegic homolog
- Serine/threonine-protein kinase Sgk1
- Mothers against decapentaplegic homolog 3
- Serine/threonine-protein kinase STK11
- Signal transducer and activator of transcription 3
Sequence:
MAEASPPGPLSPLDVELDPEFEPQSRPRSCTWPLQRPELQASPAKPAGEPPADAASMIPEEEDDDEEGGGAAMAVGGAAPAGGEAAAAGGPEEAARPPVPLPGGGPEGPGPAPGGAAAAAGGGGLSGGGPAAAAPRKCSSRRNAWGNLSYADLITRAIESSPEKRLTLSQIYDWMVRCVPYFKDKGDNNSSAGWKNSIRHNLSLHSRFIRVQNEGTGKSSWWMINPDGGKVGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAQEASEDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTISGRLSPILASTELDDVQDDDAPLSPMLYSSPSSLSPSVNKPCTVELPRLTDMAGTMNLNDGLTDNLMDDLLDNITLPSSQQSPTGGMMQRSSSFPYGSKGSGLGSPSSSFNNAVFGPSSLNSLRQSPMQTIQENKQATFSSISHYNNQTLQDLLASDALSHSDVMMTQSDPLMSQASTAVSAQNSRRNIMLRNDPMMSFAAQSSQGGLVNQSLPHHQHQSHSSPLSGSRALSNSISNIGLNDSNSLGSKHQQSPVNQSMQTLSDPLSGSSLYSSSMNLPVMGHEKFPSDLDLDIFNGSLECDMESIIRSELMDADGLDFNFDSLISAQNVVSLNVGNFTGAKQASSQSWVPG
Protein: Fatty acid-binding protein, adipocyte (3T3-L1 lipid-binding protein) (Adipocyte lipid-binding protein) (ALBP) (Adipocyte-type fatty acid-binding protein) (A-FABP) (AFABP) (Fatty acid-binding protein 4) (Myelin P2 protein homolog) (P15) (P2 adipocyte protein) (Protein 422) (P04117)
Organism: Mus musculus (Mouse)
Function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196}. Nucleus {ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196}. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus (PubMed:17516629). Subject to constitutive nuclear export (PubMed:17516629, PubMed:17761196). {ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196}.
Interaction partners:
- Hormone-sensitive lipase
- Peroxisome proliferator-activated receptor gamma
- Adiponectin
- Platelet glycoprotein 4
- Leptin
- Lipoprotein lipase
- Scavenger receptor class B member 1
- CCAAT/enhancer-binding protein alpha
- Peroxisome proliferator-activated receptor alpha
- Aspartate aminotransferase, mitochondrial
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDLVTIRSESTFKNTEISFKLGVEFDEITADDRKVKSIITLDGGALVQVQKWDGKSTTIKRKRDGDKLVVECVMKGVTSTRVYERA
Protein: RNA 3'-terminal phosphate cyclase-like protein (Q38D23)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- Nop14-like protein
- Bystin, putative
- AATF leucine zipper-containing domain-containing protein
- Uncharacterized protein
- HEAT repeat-containing protein 1
- Uncharacterized protein
- Bms1-type G domain-containing protein
- U3 small nucleolar RNA-associated protein 18
- RNA helicase
- Periodic tryptophan protein 2, putative
Sequence:
MLTFEGSSLFRHHIVCSILTSKPIRILGIHDDDEPQGIQLAEANFLKFIDRVTSGSKFECTDSNTALTFYPGMILGGTFSHEVPSCRCVTYIAEAALLLLPFAKFDTRLTLVGSTQSEEDLSVDTLRTVTTRWLQLFGVDCSVRIIRRGVYPGGGGAIEVQCKAVRRLTAAEAVVRGRVRRIRGISFGARVAADLVQRAATAAKGVLLNLLPDVYVVTDMDNSKGSYGDRSSGYGVVLVAETTSKQCVISQESTAAPKELPEDVGKRAAELLLDQVFECGCVDAHHQMLVLLLMGLSPDEVSTVRFGQFTCGLVSAVMLLEMYFGVSCATKQEWSSVGKDLPPTTLITCVGSNMVNVWKKSG
Protein: Cytochrome c oxidase assembly protein COX16, mitochondrial (P47081)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:12446688}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein eL39
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS21B
Sequence:
MSFSGKKFRSRRQQLVYEASLAGRYKKALSKHPFLFFGLPFCATIVLGSFWLSSFTAIKYEQGDRKVQEINEEDILKIRKNQREFDIKEEYYRLQGLSEEDWEPVRVARLKDESENVW
Protein: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon (I3L3T1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVKSRIKKRCRTWKTKISET