wanglab/gogpt-training-data huggingface dataset:
Protein: Neuropeptide S receptor (G-protein coupled receptor 154) (P0C0L6)
Organism: Rattus norvegicus (Rat)
Function: G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q6W5P4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q6W5P4}.
Interaction partners:
- Neuropeptide S
- FAU ubiquitin like and ribosomal protein S30 fusion like 2
- Ubiquitin-like protein FUBI
- Elongation factor Tu, mitochondrial
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein bL9m
- Large ribosomal subunit protein bL12m
Sequence:
MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALEAEEWGSFYSSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRIVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGAEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISVIYGLVIRTIWIKSKAHETVISNCSDGELCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDMLDNFNLLPDTKERFYASVIIQNLPALNSAINPLIYCIFSGSLCSPCKVQRSQDSRMTYRERSERHEMQILSKPEFI
Protein: L-type lectin-domain containing receptor kinase IV.4 (LecRK-IV.4) (EC 2.7.11.1) (O81291)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9LSR8}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MFFIKLFTIFFLSFFWQSLKSSSQIIDFTYNGFRPPPTDISILGIATITPNGLLKLTNTTMQSTGHAFYTKPIRFKDSPNGTVSSFSTTFVFAIHSQIPIAHGMAFVIAPNPRLPFGSPLQYLGLFNVTNNGNVRNHVFAVELDTIMNIEFNDTNNNHVGIDINSLNSVKSSPAGYWDENDQFHNLTLISSKRMQVWVDFDGPTHLIDVTMAPFGEVKPRKPLVSIVRDLSSVLLQDMFVGFSSATGNIVSEIFVLGWSFGVNGEAQPLALSKLPRLPVWDLKPTRVYRFYKNWVPLISLLLIPFLLIIFLVRFIMKRRRKFAEEVEDWETEFGKNRLRFKDLYYATKGFKDKNILGSGGFGSVYKGIMPKTKKEIAVKRVSNESRQGLKEFVAEIVSIGQMSHRNLVPLVGYCRRRDELLLVYDYMPNGSLDKYLYNSPEVTLDWKQRFKVINGVASALFYLHEEWEQVVIHRDVKASNVLLDAELNGRLGDFGLAQLCDHGSDPQTTRVVGTWGYLAPDHIRTGRATTTTDVFAFGVLLLEVACGRRPIEINNQSGERVVLVDWVFRFWMEANILDAKDPNLGSEYDQKEVEMVLKLGLLCSHSDPLARPTMRQVLQYLRGDAMLPDLSPLDLRGSGIMLGTHNGSNESGMFTSGSSVAYSLLSSGR
Protein: Haptoglobin-hemoglobin receptor (Q581F2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEKPSCRGAGWAQLLWCYGTCCALLLRLIVEASQAAEGLKTKDEVEKACHLAQQLKEVSITLGVIYRTTERHSVQVEAHKTAIDKHADAVSRAVEALTRVDVALQRLKELGKANDTKAVKIIENITSARENLALFNNETQAVLTARDHVHKHRAAALQGWSDAKEKGDAAAEDVWVLLNAAKKGNGSADVKAAAEKCSRYSSSSTSETELQKAIDAAANVGGLSAHKSKYGDVLNKFKLSNASVGAVRDTSGRGGKHMEKVNNVAKLLKDAEVSLAAAAAEIEEVKNAHETKAQEEMKRNGNPIENESETNSGGNAESQGNGDREDKNDEQQQVDEEETKVENGSSEEGSCCGNESNGPHVMKKRHGVEGPRPVDVVSGFRSYASASFALLSLVRVGMLQVVV
Protein: ADAM6 (Q8CGQ1)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MLSLTWGMRLVERPVVPRVLLLLFALWLLLLVPVWCSQGHPTWRYISSEVVIPRKEIYHTKGLQAQRLLSYSLRFRGQRHIIHLRRKTLIWPRHLLLTTQDDQGALQMEYPFFPVDCYYIGYLEGIPQSMVTVDTCYGGLSGVIKLDNLTYEIKPLNDSQSFEHLVSQIVSESDDTGPMNAWKHWSHNTGSPSSRLEYADGAPRLSSKNYATHPAAIKGHFQATHSVYSASGGDKLSSTVEYLFKVISLMDTYLTNLHMRYYVFLMTVYTEADPFSQDFRVPGGQAHTFYERVFYAHFRPDAGAIINKNSPGDDAVNPAERSICSPSALICLGQHGRNPLFLSIIITNRVGRSLGLKHDEGYCICQRRNTCIMFKNPQLTDAFSNCSLAEISNILNTPGLMPCLFYDRHVYYNTSLTYKFCGNFKVDNNEQCDCGSQKACYSDPCCGNDCRLTPGSICDKELCCANCTYSPSGTLCRPIQNICDLPEYCSGSKFICPDDTYLQDGTPCSEEGYCYKGNCTDRNIQCMEIFGVSAKNANIKCYDINKQRFRFGHCTRAEESLTFNACADQDKLCGRLQCTNVTNLPYLQEHVSFHQSVISGVTCFGLDEHRGTETADAGLVRHGTPCSRGKFCDRGACNGSLSRLGYDCTPEKCNFRGVCNNRRNCHCHFGWSPPKCKEEGHSGSIDSGSPPVQRRIIKQNLEPVVYLRILFGRIYFLFVALLFGIATRVGVTKIFRFEDLQAALRSWQEQAKDK
Protein: 3-hydroxypropionyl-coenzyme A synthetase (3-hydroxypropionyl-CoA synthetase) (EC 6.2.1.36) (A4YGR1)
Organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Function: Plays a role in the autotrophic CO(2) fixation pathway. Activates 3-hydroxypropionate to its CoA ester. Can also activate propionate, and to a lesser extent acrylate, acetate and butyrate.
Interaction partners:
- 3-hydroxypropionyl-coenzyme A dehydratase
- 3-hydroxypropionate dehydrogenase
- Acryloyl-coenzyme A reductase
- Citrate synthase
- Citrate synthase
- CoA-binding domain protein
- malate synthase
Sequence:
MFMRYIMVEEQTLKTGSQELEEKADYNMRYYAHLMKLSKEKPAEFWGSLAQDLLDWYEPWKETMRQEDPMTRWFIGGKINASYNAVDRHLNGPRKFKAAVIWESELGERKIVTYQDMFYEVNRWANALRSLGVGKGDRVTIYMPLTPEGIAAMLASARIGAIHSVIFAGFGSQAIADRVEDAKAKVVITADAYPRRGKVVELKKTVDEALNSLGERSPVQHVLVYRRMKTDVNMKEGRDVFFDEVGKYRYVEPERMDSNDPLFILYTSGTTGKPKGIMHSTGGYLTGTAVMLLWSYGLSQENDVLFNTSDIGWIVGHSYITYSPLIMGRTVVIYESAPDYPYPDKWAEIIERYRATTFGTSATALRYFMKYGDEYVKNHDLSSIRIIVTNGEVLNYSPWKWGLEVLGGGKVFMSHQWWQTETGAPNLGYLPGIIYMPMKSGPASGFPLPGNFVEVLDENGNPSAPRVRGYLVMRPPFPPNMMMGMWNDNGERLKKTYFSKFGSLYYPGDFAMVDEDGYIWVLGRADETLKIAAHRIGAGEVESAITSHPSVAEAAVIGVPDSVKGEEVHAFVVLKQGYAPSSELAKDIQSHVRKVMGPIVSPQIHFVDKLPKTRSGKVMRRVIKAVMMGSSAGDLTTIEDEASMDEIKKAVEELKKELKTS
Protein: GTPase MTG2, mitochondrial (Mitochondrial GTPase 2) (P38860)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for mitochondrial protein synthesis. May be involved in mitochondrial ribosome biogenesis.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:15591131}; Peripheral membrane protein {ECO:0000269|PubMed:15591131}; Matrix side {ECO:0000269|PubMed:15591131}.
Interaction partners:
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein bL32m
- Large ribosomal subunit protein bL17m
- Mitochondrial GTPase 1
- Large ribosomal subunit protein bL36m
- rRNA methyltransferase 2, mitochondrial
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein uL11m
- MIOREX complex component 8
Sequence:
MSIAWSSVFKRELRLERFLPRVYSTKVPDNAPRAADNEQWLETLRPITHPEQKKSDHDVSYTRHINVPLGEVTSVNYLQRYNKHKHSQGNFVDVRIVKCKSGAGGSGAVSFFRDAGRSIGPPDGGDGGAGGSVYIQAVAGLGSLAKMKTTYTAEDGEAGAARQLDGMRGRDVLIQVPVGTVVKWCLPPQKVRELVEREMRKDNNATLRSILGSTAVNLSVSSGSHRKKIQLYRHEMAESWLFKDKAKEYHENKDWFKDLHKKMEAYDHSLEQSELFNDQFPLAGLDLNQPMTKPVCLLKGGQGGLGNMHFLTNLIRNPRFSKPGRNGLEQHFLFELKSIADLGLIGLPNAGKSTILNKISNAKPKIGHWQFTTLSPTIGTVSLGFGQDVFTVADIPGIIQGASLDKGMGLEFLRHIERSNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKVKTKNILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREENIDVLKKKMFKCARQSEFDK
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) (NADH-ubiquinone oxidoreductase 19 kDa subunit) (P51970)
Organism: Homo sapiens (Human)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:21310150}; Peripheral membrane protein {ECO:0000269|PubMed:21310150}. Mitochondrion intermembrane space {ECO:0000269|PubMed:21310150}. Mitochondrion {ECO:0000269|PubMed:23676665}.
Interaction partners:
- NADH-ubiquinone oxidoreductase chain 2
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 3
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase 1 alpha subcomplex subunit 1
- NADH dehydrogenase 1 alpha subcomplex subunit 11
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
Sequence:
MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRPDLGELSKVTKVKTDRPLPENPYHSRPRPDPSPEIEGDLQPATHGSRFYFWTK
Protein: Cell division control protein, putative (Q57ZS5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Splicing factor 3A, putative
- SURP motif domain-containing protein
- Pre-mRNA-splicing factor SLU7
- RNA helicase
- Spliceosome-associated protein, putative
- Peptidyl-prolyl cis-trans isomerase
- G10 protein
- Sm protein G
- Sm protein B
- U5 small nuclear ribonucleoprotein component, putative
Sequence:
MTRLHFKGGAWTNSEDQVLRASLTVYGLQNWERVASTLVKKTATQCRERWENFLDPRLNINEAWTAEEEENLVQLQSLFPNQWSLISQEVSRRCGMNRPAWLCEEQYHSLLDALEYRRQQESSESRNSASLTLGEFLEERKRQRGVHRGIETRTARPDAVNMEASEKEMVEFAMSRLANQDGKKGLRKERRKQLEHTSFLAKLQSNREAIESGTLSARAKKRMERAMMEDRSGPSEAYLVDSITEDIGEGGEGEESIASTKGKFQPIDLGTDKRAAGIQPKQRVLVKELRSTVDSDAGLPPPKGASSTGLNLNLLRVASAGAASLTPQLENNKVVASLEWVSKSTGSGCSVGEPRSDADPSSVGHERVDLDDLFASLPRVVDESRKLVAGTETNIDTLFGDLPDPFPGNHEAEEGLKEVPSAPASEDFGRSSSRPSVGSVGDTPVLLDFTSPSGRTLLGEAKRRVAAVGRHMFLHSKRSRGDSYEQCQGVNEVVNDDLGDGTTRQLVYALIANQLGITTQLLLHGSAARKGCVNGPGAITQQRKGVGAASLGLRRGGGVLDEQVSKVAECQEESDPDLWRSVKASEAIIQLDNQLHQQRGQVEALVSECSESVGSGKPGVKCPERIISVCFSPRSGYTYVCPTASGTAAKYGAKGYGCGIHRLVQSICLFWSERLREAQRKLIFYTEVRRAEQREMKRRLECVASQLEAVEQKERTLQEEFRNKQVS
Protein: Glycerol-3-phosphate acyltransferase (Q9XQR1)
Organism: Oryza sativa (Rice)
Interaction partners:
Sequence:
EPFDYYMFGQNYIRPLVDYRNSYVGNISIFQDMEQKLQQGHNVVLMSNHQTEADPAIIALLLERSNPWISENIVYVAGDRVVTDPLCKPFSMGRNLICVYSKKHM
Protein: Protein E6 (Q81964)
Organism: Human papillomavirus 59
Subcellular location: Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04006, ECO:0000256|RuleBase:RU363123}. Host nucleus {ECO:0000256|HAMAP-Rule:MF_04006, ECO:0000256|RuleBase:RU363123}.
Interaction partners:
Sequence:
MARFEDPTQRPYKLPDLSTTLNIPLHDIRINCVFCKGELQEREVFEFAFNDLFIVYRDCTPYAACLKCISFYARVRELRYYRDSVYGETLEAETKTPLHELLIRCYRCLKPLCPTDKLKHITEKRRFHNIAGIYTGQCRGCRTRARHLRQQRQARSETLV
Protein: Candida glabrata strain CBS138 chromosome I complete sequence (Q6FQ06)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome J complete sequence
- Candida glabrata strain CBS138 chromosome F complete sequence
Sequence:
MISKDNEIRKLMESVAPIKVHQYKSYYMKYIEWCEQKELLSFESNSSIPYENVPLLPQLVHLFLLECVIKWPIVASDVNELQIYIESFRFLKKLCDIHSEVDPNSEFDDYITDVLELHRRWDSLLKDESQSSQLNKMATLSINMWNSNTQELSDKYFKTSMEKLRFLTDYHFYTLLNWPYKERSKLKLSHLKVHNVENDENSLNAYRLIIINDDGAVQGTVIPHDCPLICPITTLAAYLYLRFYGVKPIYRGDGFPELTKDFDLPLIRGKSLKDYPREETLGNYYSSAFKYCSLEYKRRVYLHGSSDEKNGVKNIRYPDTSNPAYKEFLTDYPNNEEMKFDRLFPAHIPLDYERIFNYSNYDGVQDGLTIPEITELPPNDLLVQVFPEIEKYKRESYNILTTKSKEFLKVLEVLRNVLVINLPWIYRYFPDHEIFSDQTSIFQNSDFVSYFNERIALISNNDSTIDINSIPPPLRNIPGYHTGLIENNIMLQYLVEPNFKAGVKSDSIPSVHDSIYNIPVTGNEGQSSSVALAPPITNNSGWKKEAFKLVQFQTLSNFNPMIDTFKKVFEKLDMKRSTREFIINKFETLTKYVNARLNSVTSEEITSYFDDILEKKNGLRYINKESNSVDKQISGRDVVDNLKRKKQKQKRRFKLLSVDDSSSGTDDANEDSVNDSSTESDSSTDDLHEEENAMQEQISSMIDELVTKKLSTLFDVKFEQMEMKLESLVKNTVSEKFNHYIAQESKKRSYEGDFEIDNTKKIRKSIDDGIKEKFNDKVNTSSTGAEEEHFVFRMADTLDSIDEIIQEWYTPDPKQGNMCVHSMNKKYKSKWRTGFEKIYRERKPIVDFFIYLVNMEKLSRSKALSICWELKSQNNFTVSELSAYLKSWKEKNNSTFVGLLNQIQHT
Protein: Prostaglandin E2 receptor EP4 subtype (Prostanoid EP4 receptor) (A0A0A7MA29)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MSGMNNGTMTSGPREPTIPVIMFIFGVVGNVIAIVVLRKSRKEQKETTFYTLVCGLAVTDLLGTLLASPVTIATYVQGKWPGGESLCQYSGFILLFFFLVGLSIICAMSIERYLAINHAYFYNHYVDQRLAALTLAGIYISNVLFCALPAMGLGKVNKQFPGTWCFIDWRTNDSAHAAFSYMYAGVSSFLILATVICNVLVCGALIMMHKRFIRRTSLGTDQGGRIADLRRRRSFQRLAGAEIQMVILLIATSAVVLVCSIPLVLRVFVNQLSMVAFDAHSTPLEKNPDLHAIRIASINPILDPWIYILLRKTVLLKLVEKIKCLFCRMGCRGRGSGVRGQFHCGGEGHPNSSIVSRDSPSLVSRELREVISTSQTFLYLPEGTGGGSRGTGGEGRPSPPAVECSLLQDQQTPGGKGMQNDSKKGTLGPSISMRTDGTVDPSPLNRVPSVRKDKTLHVTFTDETLNLQEKCI
Protein: Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89) (Q62806)
Organism: Rattus norvegicus (Rat)
Function: Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.
Subcellular location: Nucleus {ECO:0000269|PubMed:8943318}.
Interaction partners:
Sequence:
MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQTDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKPEKKSSGMDKESVLDKSDTKKDRNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQSQTISPLSTYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDENTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG
Protein: Cell division control protein 42 homolog (CDC42Ce) (Q05062)
Organism: Caenorhabditis elegans
Function: Plays an essential role in spindle orientation and organizing cellular and embryonic polarity by controlling the localization and activity of PAR (partitioning-defective) proteins. Required for maintaining the asymmetric cortical localization of the anterior complex proteins par-3 and par-6, the posterior cortical protein par-2, and pkc-3. Involved in hypodermal cell fusion, together with pak-1 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. During gonad morphogenesis, plays a role in distal tip cell (DTC)-mediated guidance of gonad elongation, probably by activating max-2. May play a role in controlling canal length and in maintaining Golgi and ER stability during excretory canal elongation, probably downstream of ccm-3, which may regulate its activity and expression levels. May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis. Involved in toca-1 and toca-2-mediated protein trafficking controlling the recycling of endocytic cargo protein mig-14 to the Golgi apparatus. Plays a role in male tail tip morphogenesis. Together with kpc-1 and chin-1, plays a role in guiding axons from neurons, including AIY interneurons, into the nerve ring.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27506200, ECO:0000269|PubMed:8824291}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000269|PubMed:21408209, ECO:0000269|PubMed:8824291}. Recycling endosome {ECO:0000269|PubMed:25775511}. Cytoplasm {ECO:0000269|PubMed:21408209}. Note=Co-localizes with ced-10/rac-1 and pak-1 at hypodermal cell boundaries during embryo elongation (PubMed:8824291). Localizes in punctate cytoplasmic structures along the length of excretory canals (PubMed:25743393). Co-localizes with rme-1 and toca-1 on recycling endosomes (PubMed:25775511). Diffusely localizes in the cytoplasm of tail tip cells, but then localizes to the apical surfaces of the tail tip cells before male tail tip retraction during the L4 larval stage (PubMed:21408209). During male tail tip retraction localizes to the cytoplasm (PubMed:21408209). {ECO:0000269|PubMed:21408209, ECO:0000269|PubMed:25743393, ECO:0000269|PubMed:25775511, ECO:0000269|PubMed:8824291}.
Interaction partners:
- Serine/threonine-protein kinase pak-1
- Probable rho GDP-dissociation inhibitor
- Protein kinase C-like 3
- Intersectin-1
- Partitioning defective protein 6
- Actin
- CRIB domain-containing protein
- Serine/threonine-protein kinase max-2
- DH domain-containing protein
- Serine/threonine-protein kinase mrck-1
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGTQVDLRDDPGMLEKLAKNKQKPVSTDVGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALDPPQQEKKKKCNIL
Protein: Large ribosomal subunit protein mL43 (39S ribosomal protein L43, mitochondrial) (L43mt) (MRP-L43) (Retina-specific 15.7 kDa protein) (Q95KE5)
Organism: Bos taurus (Bovine)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q8N983}.
Interaction partners:
- MRPL41 protein
- Large ribosomal subunit protein mL49
- Small ribosomal subunit protein uS10m
- Large ribosomal subunit protein uL11m
- Small ribosomal subunit protein uS7m
- Large ribosomal subunit protein mL44
- Ribosomal protein
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein bL34m
- Large ribosomal subunit protein mL63
Sequence:
MTARGTASRFLTSVLHNGLGRYVQQLQRLSFSLSRDAPSSRGAREFVEREVTDFARRNPGVVIYVNPRPCCVPRVVAEYLNGAVREESLNCKSVEEIATLVQKLADQSGLDVIRIRKPFHTDSPSIQGQWHPFTNKPTALGGLRPREVQNPAPTQRPAQ
Protein: Centrosomal protein 20 (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa) (LisH domain-containing protein FOPNL) (Q96NB1)
Organism: Homo sapiens (Human)
Function: Involved in the biogenesis of cilia. Required for the recruitment of PLK1 to centrosomes and S phase progression.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:26643951}. Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20551181, ECO:0000269|PubMed:24018379}. Cytoplasmic granule {ECO:0000269|PubMed:20551181}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:20551181, ECO:0000269|PubMed:26643951}. Note=Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951). {ECO:0000269|PubMed:24018379, ECO:0000269|PubMed:26643951}.
Interaction partners:
- Homeobox protein goosecoid
- Centriole and centriolar satellite protein OFD1
- Protein moonraker
- Pre-mRNA-splicing factor ISY1 homolog
- Pre-mRNA-splicing factor ISY1 homolog
- Pericentriolar material 1 protein
- Meiosis regulator and mRNA stability factor 1
- bMERB domain-containing protein 1
Sequence:
MATVAELKAVLKDTLEKKGVLGHLKARIRAEVFNALDDDREPRPSLSHENLLINELIREYLEFNKYKYTASVLIAESGQPVVPLDRQFLIHELNAFEESKDNTIPLLYGILAHFLRGTKDGIQNAFLKGPSLQPSDPSLGRQPSRRKPMDDHLRKEEQKSTNIEDLHVSQAVNR
Protein: Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) (P49795)
Organism: Homo sapiens (Human)
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Subcellular location: Membrane; Lipid-anchor.
Interaction partners:
- PDZ domain-containing protein GIPC1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-5
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-11
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
Protein: Replication factor C subunit 2 (AtRFC2) (Activator 1 subunit 2) (Protein EMBRYO DEFECTIVE 2811) (Q9CAM7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in DNA replication and thus regulate cell proliferation.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Replication factor C subunit 5
- Checkpoint protein
- Cell cycle checkpoint protein RAD17
- Replication factor C subunit 3
- Chromosome transmission fidelity protein 18 homolog
- Proliferating cellular nuclear antigen 1
- Replication factor C subunit 4
- Replication factor C subunit 1
- Proliferating cell nuclear antigen 2
- DNA polymerase alpha subunit B
Sequence:
MASSSSTSTGDGYNEPWVEKYRPSKVVDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGTNYKEAVLELNASDDRGIDVVRNKIKMFAQKKVTLPPGRHKVVILDEADSMTSGAQQALRRTIEIYSNSTRFALACNTSAKIIEPIQSRCALVRFSRLSDQQILGRLLVVVAAEKVPYVPEGLEAIIFTADGDMRQALNNLQATFSGFSFVNQENVFKVCDQPHPLHVKNIVRNVLESKFDIACDGLKQLYDLGYSPTDIITTLFRIIKNYDMAEYLKLEFMKETGFAHMRICDGVGSYLQLCGLLAKLSIVRETAKAP
Protein: ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) (Q9HV48)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01458}; Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01458}; Cytoplasmic side {ECO:0000256|HAMAP-Rule:MF_01458}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Protein HflC
- Protein HflK
- Protease HtpX
- Ribosomal RNA large subunit methyltransferase E
- ATP-dependent Clp protease ATP-binding subunit ClpX
- Protein HflC
- Dihydropteroate synthase
- UDP-3-O-acyl-N-acetylglucosamine deacetylase
- Phosphoglucosamine mutase
- Small ribosomal subunit protein uS5
Sequence:
MAKNLILWLIIAAVLVTVMNNFSSPSEPQTLNYSDFIQQVKDGKVERVTVDGYVITGKRSDGDTFKTIRPAIQDNGLIGDLVNNNVVVEGKQPEQQSIWTQLLVASFPILVIIAVFMFFMRQMQGGGGGRGGPMSFGKSKARLLSEDQVKTTFADVAGCDEAKEEVSELVEFLRDPGKFQRLGGRIPRGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFDQAKKHAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFEMNDGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDIRGREQILKVHMRKVPLGDHVDPAVIARGTPGFSGADLANLVNEASLFAARSNKRIVDMREFELAKDKIMMGAERKTMVMSEKEKRNTAYHEAGHAIVGRLVPEHDPVYKVSIIPRGRALGVTMFLPEEDRYSLSKRALESQICSLFGGRIAEEMTLGFEGVTTGASNDIMRATQLARNMVTKWGLSEKLGPLMYAEEEGEVFLGRSAGSQHANVSGETAKMIDQEVRRIIDDCYGTAKRLLDENRDKLEMMADALMKYETIDSDQIDDIMAGRVPREPRDWQGGSGTGTPPANLEESGRRENTPPIGGPAGEH
Protein: Glutaredoxin-C8 (AtGrxC8) (Protein ROXY 2) (Q8LF89)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). Involved in flower development.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P17695}. Nucleus {ECO:0000269|PubMed:20805327}.
Interaction partners:
- Transcription factor TGA9
- Transcription factor TGA10
- Transcription factor TGA2
- Protein TAPETUM DETERMINANT 1
- Transcription factor PERIANTHIA
- Transcription factor DYT1
- Protein SPOROCYTELESS
- Monothiol glutaredoxin-S17
Sequence:
MQYKTETRGSLSYNNNSKVMNNMNVFPSETLAKIESMAAENAVVIFSVSTCCMCHAIKRLFRGMGVSPAVHELDLLPYGVEIHRALLRLLGCSSGGATSPGALPVVFIGGKMVGAMERVMASHINGSLVPLLKDAGALWL
Protein: DnaJ-like protein 60 (P92029)
Organism: Drosophila melanogaster (Fruit fly)
Function: May play an important function during spermatogenesis and/or in the male genital tract.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Heat shock 70 kDa protein cognate 5
- GrpE protein homolog, mitochondrial
Sequence:
MLRLCLPTRAGYVRNFSNDKPRKPETHYEVLNIRNDCSTREVRNAFVQLSKLYHPDVKSNAACPERTARFVQISEAYKTLIKPERRRDYDDSLLWQPSRSDRSPVGETVNPGQAWDVRPNYDPNPGPYYGIRGLKRVSNWQVAVVLMALGFVGALFGFTSVRSSFKLSRQIQDEISAEANSHHAAVVADAQKYGNEEQVRRMVDRMSRSPFNQSSAK
Protein: Uncharacterized protein (Q4GYG2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQIYVKHRGKFIFLALWSGFTCIAMFWLMIRRSGFGTSYSRCCYLVMWGEYKQLLEPGTFPSNGFLPPHLRLDSRSYLDLPETEIALPPLIDVSIAERDQVRNLESMLPSTQRSDLKVQFGPIRTQTIVMTSGANERYVRRRLGLSEKDRKRLQEEEQQKAVEVNK
Protein: Myelin protein zero-like protein 2 (Epithelial V-like antigen 1) (O70255)
Organism: Mus musculus (Mouse)
Function: Mediates homophilic cell-cell adhesion.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MYGKSPALVLPLLLSLQLTALCPTEAVEIYTSGALEAVNGTDVRLKCTFSSFAPVGDALTVTWNFRPRDGGREQFVFYYHMDPFRPMSGRFKDRVVWDGNPERYDVSILLWKLQFDDNGTYTCQVKNPPDVDGLVGTIRLSVVHTVPFSEIYFLAVAIGSACALMIIVVIVVVLFQHFRKKRWADRADKAEGTKSKEEEKLNQGNKVSVFVEDTD