wanglab/gogpt-training-data huggingface dataset:
Protein: Peptidoglycan endopeptidase RipA (EC 3.4.-.-) (Macrophage invasion and intracellular persistence protein A) (Resuscitation-promoting factor interaction partner A) (Rpf-interacting protein A) (O53168)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.
Subcellular location: Secreted {ECO:0000269|PubMed:17919286, ECO:0000269|PubMed:26933057}. Note=Secreted by the TAT secretion pathway (PubMed:26933057). Localizes to the septa upon expression in M.bovis or M.smegmatis. Remains associated with the cell. {ECO:0000269|PubMed:26933057}.
Interaction partners:
- Peptidoglycan endopeptidase RipB
- Resuscitation-promoting factor RpfB
- Resuscitation-promoting factor RpfE
- N-acetylmuramoyl-L-alanine amidase Rv3717
- N-acetylmuramoyl-L-alanine amidase CwlM
- Possible Inv protein
- Cell wall hydrolase ChiZ
- Exported repetitive protein
- Probable peptidoglycan glycosyltransferase FtsW
- Chaperone MoxR1
Sequence:
MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRLQDLSDEVQAEQESVNKAMVDVETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFAAATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMANLQRARTERVNTESAARLAKQKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSEGGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQVTANMGRKFLEQLGILQPTDTGITNAPAGSAQGRIPRVYGRQASEYVIRRGMSQIGVPYSWGGGNAAGPSKGIDSGAGTVGFDCSGLVLYSFAGVGIKLPHYSGSQYNLGRKIPSSQMRRGDVIFYGPNGSQHVTIYLGNGQMLEAPDVGLKVRVAPVRTAGMTPYVVRYIEY
Protein: Gap junction protein (Q8AWR4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, gap junction {ECO:0000256|ARBA:ARBA00004610}. Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}.
Interaction partners:
Sequence:
MGDFSSLGKLLESAQEHSTVVGKVWLTVLFIFRILVLSAAAEKVWGDEQSGFTCDTKQPGCQNVCYDVTFPISHIRFWVLQIIFVSTPTLIYLGHILHLVRMEQKLKSNETSGADKQALLGHKPKGPIRDEQGKICLKGVLLRTYVFNIIFKTLFEVGFIVAQYFLYGFELKPLYTCSRWPCPNTVNCYISRPTEKTIFIIFMLAVACVSLLLNLVEMYHLGFTKCRQGLRYRRAHSVCDTESKVPSEDVVVPFVPNYPYFPAHAPPPASFPTEPHFNLSEPDGTFPVHNSRSVYKQNRENMAVERNGKPDTADVKISKTVSSVPGSPSSQQRRPSHSSRYSSNKTRMDDLKI
Protein: Dynactin subunit 2 (Dynamitin) (Dynactin 2 p50 subunit) (Q7K2D2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Actin-related protein 10, isoform A
- Actin-related protein 1
- Dynactin subunit 4
- CG9893 protein
- Dynactin subunit 1
- Dynactin subunit 6
- Dynactin subunit 5
- Protein bicaudal D
- Dynactin subunit 1
- F-actin-capping protein subunit beta
Sequence:
MADPKFQNLPGIAYDQPDVYETPDDPELDTSDYYEEEPENEAIERLHISPSVAHKRFSGATVEGSVDFTDRIGRRMCRGYDTRGSSDYELVGQGEKETPVQKCQRLQIEMNELLNEVAALQVDRKVADEEKQSYDAVATVISTARKVLESLKLEQVLGKEQTPGSKQVKALISQVEEFKQSGVLTAIPTPGTDLAATARVASLEQRISQLEKVLGAQPDKLSRLTAATNTTNVLEAVRHLSTKAALIQPDKLDTIEQRLTSLAGKMDAIAEKSSGSAQDAKRDQKITELYDIAKRTEPVVEILPHVIERMQALEALHKYANNFAKIIAEIEQKQGTITTSLVNNKELLHSVQETFAQNLETINSKVAKVEQRVAAISSAK
Protein: Ras-related protein Rab (Q7KY07)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|RuleBase:RU367128}; Lipid-anchor {ECO:0000256|RuleBase:RU367128}.
Interaction partners:
Sequence:
MPAFGDLTMDQEMEPAIMTSTSDKREHLYKILVIGELGTGKTSFIKRYVHQFFSQNYRATIGVDFALKVLQWDANTIVRLQLWDIAGQERFGNMTRVYYKEAVGAFIVFDVTRSGTFDCVSKWKEDLDSKVQLPDGSPIPCILLANKCDQEKQGIITQPEKMDEYVRENGFAGWFETSAKENINIDEAARALVNKILINDKLISADLADGDKFNLSAADATGSDAKNKCSC
Protein: Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (Q5QNY5)
Organism: Homo sapiens (Human)
Subcellular location: Peroxisome membrane {ECO:0000256|ARBA:ARBA00004405}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004405}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004405}.
Interaction partners:
Sequence:
MESGALDDFDKAKPSPAPPSTTTAPDASGPQKRSPGDTAKDALFASQEKFFQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDMTSQQEFTSCLKETLSGLAKNATDLQNSSMSEEELTKAMEGLGMDEGDGEGNILPIMQSIMQNLLSKDVLYPSLKEITEKYPEWLQSHRESLPPEQFEKYQEQHSVMCKICEQFEAETPTDSETTQKARFEMVLDLM
Protein: Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (P83917)
Organism: Mus musculus (Mouse)
Function: Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P83916}. Note=Unassociated with chromosomes during mitosis. {ECO:0000250}.
Interaction partners:
- E3 ubiquitin-protein ligase RING1
- Polycomb complex protein BMI-1
- Solute carrier family 25 member 3
- Histone H3.3
- Histone H3.1
- Histone H3.2
- Histone-lysine N-methyltransferase SUV39H1
- Polycomb group RING finger protein 2
- Transcription intermediary factor 1-beta
- Histone deacetylase 1
Sequence:
MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
Protein: Delta-6 fatty acyl desaturase (Delta-6 fatty acyl desaturase isoform X1) (Q6SES0)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- HRAS-like suppressor 3
- Retinoic acid receptor responder protein 3
- HRAS-like suppressor 3
- Retinoic acid receptor responder protein 3
- Elongation of very long chain fatty acids protein 5
- Elongation of very long chain fatty acids protein 2
- Lathosterol oxidase
- Elongation of very long chain fatty acids protein 5
Sequence:
MGGGGQQNDSGEPAKGDRGGPGGGLGGSAVYTWEEVQRHSHRGDQWLVIDRKVYNITQWAKRHPGGIRVISHFAGEDATDAFVAFHPNPNFVRKFLKPLLIGELAPTEPSQDHGKNAVLVQDFQALRNRVEREGLLRARPLFFSLYLGHILLLEALALGLLWVWGTSWSLTLLCSLMLATSQSQAGWLQHDYGHLSVCKKSSWNHVLHKFVIGHLKGASANWWNHRHFQHHAKPNVLSKDPDVNMLHVFVLGDKQPVEYGIKKLKYMPYHHQHQYFFLIGPPLLIPVFFTIQIFQTMFSQRNWVDLAWSMTFYLRFFCSYYPFFGFFGSVALITFVRFLESHWFVWVTQMNHLPMEIDHERHQDWLTMQLSGTCNIEQSTFNDWFSGHLNFQIEHHLFPTMPRHNYHLVAPLVRTLCEKHGIPYQVKTLQKAIIDVVRSLKKSGDLWLDAYLHK
Protein: Receptor-like protein kinase At3g21340 (EC 2.7.10.1) (EC 2.7.11.1) (Leucine-rich repeat receptor-like protein kinase At3g21340) (Q9LIG2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Splicing factor, CC1-like protein
- Adenine nucleotide alpha hydrolases-like superfamily protein
- Ribosome biogenesis protein NSA2 homolog
- Vacuolar protein sorting-associated protein 53 B
- Ras-related protein RABG2
Sequence:
MEYHPQAIRLCALIFISFYALLHLVEAQDQKGFISLDCGSLPNEPPYNDPSTGLTYSTDDGFVQSGKTGRIQKAFESIFSKPSLKLRYFPDGFRNCYTLNVTQDTNYLIKAVFVYGNYDGLNNPPSFDLYLGPNLWVTVDMNGRTNGTIQEIIHKTISKSLQVCLVKTGTSSPMINTLELRPLKNNTYNTQSGSLKYFFRYYFSGSGQNIRYPDDVNDRKWYPFFDAKEWTELTTNLNINSSNGYAPPEVVMASASTPISTFGTWNFSWLLPSSTTQFYVYMHFAEIQTLRSLDTREFKVTLNGKLAYERYSPKTLATETIFYSTPQQCEDGTCLLELTKTPKSTLPPLMNALEVFTVIDFPQMETNPDDVAAIKSIQSTYGLSKISWQGDPCVPKQFLWEGLNCNNLDNSTPPIVTSLNLSSSHLTGIIAQGIQNLTHLQELDLSNNNLTGGIPEFLADIKSLLVINLSGNNFNGSIPQILLQKKGLKLILEGNANLICPDGLCVNKAGNGGAKKMNVVIPIVASVAFVVVLGSALAFFFIFKKKKTSNSQDLGPSSYTQVSEVRTIRSSESAIMTKNRRFTYSEVVTMTNNFERVLGKGGFGMVYHGTVNNTEQVAVKMLSHSSSQGYKEFKAEVELLLRVHHKNLVGLVGYCDEGENLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVVESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHLHAKLADFGLSRSFPIEGETHVSTVVAGTPGYLDPEYYRTNWLNEKSDVYSFGIVLLEIITNQLVINQSREKPHIAEWVGLMLTKGDIQNIMDPKLYGDYDSGSVWRAVELAMSCLNPSSARRPTMSQVVIELNECLSYENARGGTSQNMNSESSIEVSMNFDIGATPDAR
Protein: Heterogeneous nuclear ribonucleoprotein U, MARS binding protein P120, hnRNP U=MATRIX attachment region binding protein (Q9PSP7)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
TXNXETEDFGEKFDENDVXXXFANFDDEPYFPVPEEYTFIQXDNFILDQTNVSAAAQRXXFTLPEVAEXFDEIIYVEL
Protein: Calcium-binding protein 4 (CaBP4) (Q8VHC5)
Organism: Mus musculus (Mouse)
Function: Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P57796}. Presynapse {ECO:0000269|PubMed:15452577}. Note=Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors. {ECO:0000269|PubMed:15452577}.
Interaction partners:
- Voltage-dependent L-type calcium channel subunit alpha-1F
- Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3
- Voltage-dependent L-type calcium channel subunit alpha-1D
- Nyctalopin
- Protein bassoon
- Potassium voltage-gated channel subfamily V member 2
- C-terminal-binding protein 2
- Voltage-dependent calcium channel subunit alpha-2/delta-4
- Protein S100-G
- Sodium/potassium/calcium exchanger 1
Sequence:
MATEHNVQLVPGSQKIPKGVVSPRSAAEGPALTRRRSKKESWHPGSQKASSGDQSSSQGSEASGSSKHPPRTKVGQEEPSSAPARPASHRHSHRHRSDPQQDAAQRTYGPLLNRMFGKDRELGPEELEELQAAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDEFVMMLSTG
Protein: Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (Lymphocyte antigen 5) (Ly-5) (T200) (CD antigen CD45) (P06800)
Organism: Mus musculus (Mouse)
Function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P08575}; Single-pass type I membrane protein {ECO:0000255}. Membrane raft {ECO:0000250|UniProtKB:P08575}. Synapse {ECO:0000250|UniProtKB:P08575}. Note=Colocalized with DPP4 in membrane rafts. {ECO:0000250|UniProtKB:P08575}.
Interaction partners:
- B-cell receptor CD22
- Proto-oncogene tyrosine-protein kinase LCK
- Leukosialin
- Galectin-3
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase Lyn
- Leukocyte surface antigen CD47
- T-cell surface glycoprotein CD4
- Semaphorin-4D
- Tyrosine-protein kinase HCK
Sequence:
MTMGLWLKLLAFGFALLDTEVFVTGQTPTPSDELSTTENALLLPQSDPLPARTTESTPPSISERGNGSSETTYHPGVLSTLLPHLSPQPDSQTPSAGGADTQTFSSQADNPTLTPAPGGGTDPPGVPGERTVPGTIPADTAFPVDTPSLARNSSAASPTHTSNVSTTDISSGASLTTLTPSTLGLASTDPPSTTIATTTKQTCAAMFGNITVNYTYESSNQTFKADLKDVQNAKCGNEDCENVLNNLEECSQIKNISVSNDSCAPATTIDLYVPPGTDKFSLHDCTPKEKANTSICLEWKTKNLDFRKCNSDNISYVLHCEPENNTKCIRRNTFIPERCQLDNLRAQTNYTCVAEILYRGVKLVKNVINVQTDLGIPETPKPSCGDPAARKTLVSWPEPVSKPESASKPHGYVLCYKNNSEKCKSLPNNVTSFEVESLKPYKYYEVSLLAYVNGKIQRNGTAEKCNFHTKADRPDKVNGMKTSRPTDNSINVTCGPPYETNGPKTFYILVVRSGGSFVTKYNKTNCQFYVDNLYYSTDYEFLVSFHNGVYEGDSVIRNESTNFNAKALIIFLVFLIIVTSIALLVVLYKIYDLRKKRSSNLDEQQELVERDDEKQLMDVEPIHSDILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKDARKPHNQNKNRYVDILPYDYNRVELSEINGDAGSTYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFKDIVVTINDHKRCPDYIIQKLNVAHKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAEGKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHSCLHNMKKRDPPSDPSPLEAEYQRLPSYRSWRTQHIGNQEENKKKNRNSNVVPYDFNRVPLKHELEMSKESEPESDESSDDDSDSEETSKYINASFVMSYWKPEMMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELVNGDQEVCAQYWGEGKQTYGDMEVEMKDTNRASAYTLRTFELRHSKRKEPRTVYQYQCTTWKGEELPAEPKDLVSMIQDLKQKLPKASPEGMKYHKHASILVHCRDGSQQTGLFCALFNLLESAETEDVVDVFQVVKSLRKARPGVVCSYEQYQFLYDIIASIYPAQNGQVKKTNSQDKIEFHNEVDGGKQDANCVRPDGPLNKAQEDSRGVGTPEPTNSAEEPEHAANGSASPAPTQSS
Protein: Protocadherin beta 12 (Q91Y07)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
- Protocadherin beta 9
- Protocadherin beta 3
- Protocadherin beta 4
- Protocadherin beta 11
- Protocadherin beta 10
- Protocadherin beta-8
Sequence:
MPGQRQVFFLTILLLFWKSDSEAIRYSMPEEKESGYLVANVAKDLGLRVEELATRGAQIHYRGNKELLQMDAETGNLFLKEKLDREALCGATEPCVLHFQIILENPVQFFQTELQLTDINDHSPEFSDTEMLLTIPENAQPGTVFPLKAAHDSDIGSNAVQNYTVNPNIHFHVVTLSRSDGRKYPELVLDRALDREEQPELTLTLTALDGGSPPRSGTTEVHIEVVDINDNAPQFIQSLYEVQVPENSPLNALVVMVSATDLDAGIYGNVAYSLFQGDGLSQPFVIDKITGEIRLTKELDFEVSHHYTIEIAATDGGGLSGKCTVVIQVLDVNDNAPELAIRKLTVPVPENSAETVVAVFSVSDSDSGDNGRIVCSIQNNIPFLLKPTFENYYTLVTEGPLDRESRAEYNITITVWDLGTPRLTTQHTITVQVADINDNAPAFTQTSYTLFVQENNSPALHIGTISATDSDSGSNAHITYSLLPPHDSQLALASLVSINSDNGQLFALRAMDYEMLQAFELHVDATDGGSPALSSQALVRVVVLDDNDNSPFVLYPMQNASAPCTELLPRAAEPGYLITKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDAPKHKLLLLVKDNGDPPRSASVTLHVLVVDGFSQPYLPLPEVARDSTQDDYDVLTLYLVVALASVSSLFLLSVLLFVGVRLCRRARAASLGDYSVPEGHFPSHLVDVSRAGTLSQSYQYEVCLNGGTGTNEFNFLKPLFPILPTQAAAEERENAVVRNSVEFY
Protein: 3', 5'-cyclic nucleotide phosphodiesterase, putative (EC 3.1.4.-) (Q57ZK5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Adenosine kinase
- Adenosine kinase
- AMP deaminase
- Adenosine monophosphate deaminase, putative
- AMP deaminase, putative
- adenine phosphoribosyltransferase
- adenine phosphoribosyltransferase
- Adenylosuccinate lyase
- Phosphodiesterase
- Phosphodiesterase
Sequence:
MVCYDGSHSPCGRFSQKDYDCPTCGKVFTSSTPKTVCPCCSKLCCSQCVQTECVIFSGDRPFQVCVSCFLMLRSDRDSTALNVLPLYAVPNVSSKLSRIRTATKVQPPSDTSSDRVVVDAHLRVPDAKMRMNATEKVNLERKAPLPSPRVLQQRNASVRKQESTVDTVREEKAPSVPFVGQAEKTNEGGRVVGKLQDEISRLKRENSALSSKLQEFQGHAEGAQRKVHQIATQTQIKEQAAQNPQRGGTDGAGEVVQPRQEQKSLEMVRSSSSAPMSARYSHPSIVHATILTVVPTKLQVALCEGIDFSDWGFDTLEVASLVPSALQTVAAEVVTRWKMFASEEEMQRWCHMVAAIENNYRPNPFHNAVRAADVVQAVFSLASATKPLMRHVTLVELKALVFAAVALDVRHPGRTNEFLVRTCDPLCYRYPGPGTLEQMHVATAFQLVEVPELNFTCRMNDESFLRFKTIVSKLICRTDTAVLEDHLEHWRAKAREGGFDYGAPDDRVDALSLLLLAADFGVISRGADIAAKWLVLTEEHAAQAQEERRRGLPVTPGFDLPTSVGRSQIAFLDSVVIPLFNQVQQLFPGIVEPSRNLRALRSKYAAMANPPVLSTSVVSNHGESRERQQIGETHNLLRRYHGVDDHRYVSPINTSVEGRDVLSGALEEPRAMSEGRVDHLHGKDRPFRLELGRCTGSTGTKERVNGVAGLEYTPRFLDAPTQHDYSSAPSSGKVGYSHSACPAEKGGRIDRFDQHQIAPSRCVASVPEIRIEKPPPFRSSERDAMIPQRDNALSTPIRRALNSSTSPSRWDGDDRLVRKYSEMDDLLLHVRAMRVGGGLNHDHEEKHRRLRSTLAEREAMITEAAELLRQRRQQLRSGSAARSNEILQGHADAAVLQLRVAAANASVGP
Protein: Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein) (I3L325)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQPVRTVVPVTKHRGYLGVMPAYSAAEDALTTKLVTFYEDRGITSVVPSHQATVLLFEPSNGTLLAVMDGNVITAKRTAAVSAIATKFLKPPSSEVLCILGAGVQAYSHYEIFTEQFSFKEVRIWNRTKENAEKFADTVQGEVRVCSSVQEAVAGADVIITVTLATEPILFGEWVKPGAHINAVGASRPDWRELDDELMKEAVLYVDSQEAALKESGDVLLSGAEIFAELGEVIKGVKPAH
Protein: Methionine aminopeptidase 1C, chloroplastic/mitochondrial (MAP 1C) (MetAP 1C) (EC 3.4.11.18) (Peptidase M 1C) (Q9FV51)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Subcellular location: Plastid, chloroplast {ECO:0000255|HAMAP-Rule:MF_03174, ECO:0000269|PubMed:11060042}. Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03174, ECO:0000269|PubMed:11060042}.
Interaction partners:
- Methionine aminopeptidase 2A
- Peptide deformylase 1B, chloroplastic/mitochondrial
- Peptide deformylase 1A, chloroplastic/mitochondrial
- Expressed protein
- Large ribosomal subunit protein uL18z
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein uL23y
- 60S ribosomal export protein NMD3
- Large ribosomal subunit protein eL38z/eL38y
Sequence:
MLQKISQSISLCNGDQFKPLIYLAGAPTNFISSPLSGKKKSSSLRIKRIQQLQSTLEDRINPPLVCGTVSPRLSVPDHILKPLYVESSKVPEISSELQIPDSIGIVKMKKACELAARVLDYAGTLVRPFVTTDEIDKAVHQMVIEFGAYPSPLGYGGFPKSVCTSVNECMFHGIPDSRPLQNGDIINIDVAVYLDGYHGDTSKTFLCGDVNGSLKQLVKVTEECLEKGISVCKDGASFKQIGKIISEHAAKYGYNMERFIGHGVGTVLHSEPLIYLHSNYDYELEYMIEGQTFTLEPILTIGTTEFVTWPDKWTIVTADGGPAAQFEHTILITTTGAEILTISS
Protein: Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4] (P11859)
Organism: Mus musculus (Mouse)
Function: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P01019}.
Interaction partners:
- Type-2 angiotensin II receptor
- Type-1 angiotensin II receptor B
- Type-1 angiotensin II receptor A
- Type-1 angiotensin II receptor-associated protein
- Angiotensin-converting enzyme
- Proto-oncogene Mas
- Angiotensin-converting enzyme 2
- Protachykinin-1
- Renin-1
- B2 bradykinin receptor
Sequence:
MTPTGAGLKATIFCILTWVSLTAGDRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV
Protein: GH15471p (Q7K523)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTHIESRASNGAGVSVNYSEVTHSLLSGGLKNRFLPPIPPKPPKRGILKGSRSNMTNVHEEISFAGSAGGAGGTPEMLLRNTFQNESLYEGAARGAGSIGSNSSQHGTSFTSVESLRSDGEQTGGQQRAMTLPANARYGALPQGNSQGSHLHVLTSPSPSADSLTDTTNSSFATPPFSLSPVGESQGIDRWARVHAFEDVELPLPPVQLVKLPPPRQLVIRRQKSPRQDFGFSLRKAICLDRTESLTSPIFRPVIFAEPGAGGGATGLLPGDRLIKVNGTPVGELPREIIIEMIRNSGEAVTVEVQPVAELVELSKRCMAPSTATVEEIDHSITNGNCNTLRRSASKRFKRQSRHENGNGGGEEGGAKGVGHDLEADVADASQPERVWLVHRGGFTAAIRLPTASSGRDEENKLSLRLLHNGEQLTVDEDDVEKQNSPALDLVEDICELKYLNEASVLHCLRQRYASNLIHTKAGPTLLVVNPMAPLSLYSEKVVSMFRGCKTEDMPPHVYSLAQTAYRSLVETRRDQSLIFMGRSGSGKSTSFKHALNYLALAAGAYNNFINAEKVNALCTILEAFGNTKTCLNSNATRMTQLLSLDFDQTGQIASASLQVLLPERQRAGRRLGHEHSFHIMTRLLAGAAGLLQKELHLENITSEDSHPFISLSQKLEDRHRAANDFMRTVQAFETLNIDAKAVRGIWSILAAIYHLGIAGVTKLGTGSTARTQFANPTAARKASGLLGVNLEDLSSAAFGLTQPNAPNGGLSPSKSPTSDTGHEWAWECLEALVIGLYSEALAAVVALINRQICTSSHTIASIMLIDTPGFQNPASCGQQVGATLADLRHNYLQERLQMLFHHTTLVAPRDRYAQELVEIEMDLASECHPGPLISLIDKAPQNHVVRSSQRDLREHDRRGMLWLLDEEAIYPNSNDDTFLERLFSHYGDREHHSLLRKCAGPRQFVLHHLQGTNPVLYAVDGWVRHSREHPGIRNAVSLLQDSSREEINRLYIGSLTRGSGAMVFCGSFAGLEGTQSLRRVSSIRRSFTTAGVKRNSIMLQVKFTVDGIIDTLRRTGTHFVHCYLLQHNAGKHTKYTANGSPSSAAGQVSSEEEMVNVPLLRSQLRGSQVLEAARLHRLGFPESVPLLEFVRRFGLLAGDLASNKDVSVEQILAVNELDVASYRIGPSQILFRSGVLSELEAKRDVLLSDRIIQLQAFCRGYLARKKMSQRRVQELAVRCIQRNVKAFLAVRDWPWWRLLVRVTPLLNVHRTEEQLKTANEELLMLRAKLEKIECDRSEVKAENQKLEAKLSELTVDLAEERSTAHIATERLEAETAERLKLEKELGDQTNKVKNLQETTEKLEMELICAKSDLNGISEDEDAENEDGVGGGVYKLKYERVARELEFTKRRLHTQHEHDLEQLVALKKHLEMKLSDAYEEVVEQRQVVGQWKRKAQKMTNEMNDLRMLLEEQNARNNLLEKKQRKFDAECQSLQDAVRQERQAKERYGREKDVLQAEKFTLEQTLADTRLDLEFKEEKLASLQRELEEMTFGGGTEEEFAQLRRSKNETERRAKEQEEELDEMAGQIQLLEQAKLRLEMTLETMRKEARRESQQRDEELEEVRGNGYKKIKALECQLETEHEERTLLLREKHELERRLSSMEDRDRVDRDAEEALNQKLRRDLRKYKALLKDAQTQLERLKADTPGKTLIRQLRNQLEDAESARSLAMKARQTAEAELTEVQAMFDESHRARNDAEERANAAHRDRAELQAQIEENEEELGELMKKYSATVKQLNTEQINVSEAEFKLNEMEAERNNLKEQVAELQHRLDNVENLGDPSMAMMSKRLELRTKELESRLELEQATRARLEVQVNRHKEALEKLQNEVTQSKMREMQAQDVIKKSQKSLRDMREEFHAVSSREQESLTRRKDLEKKVEQMESEGAALKNDLRLALQRIADLQQAMEEEGEEELSESDESLSSVGSISDLEDRLRPVHVKRSSQQSLNGSIGGGGGSVVSSTRTVVFEKDDNSPRNNAK
Protein: Prage, isoform A (Prage, isoform C) (Prage, isoform F) (Q9W557)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MHFFLEDFLQAHLPKIYDKMQSCNKNSSSRITTTNNNVTTTSNISGNSSNKRCPQKYTGNTLAVNSNMLAYQQQATAGGKNSTRKSRHNNNKQNHQQQQQQQQQQFDHIHKRNGTAGGTGSECSPAAPTSNWLQRGYGRQFVHSSCIEDKLLGHHNPGHRNSTSSDATSEDIDSSSELPNKSKGNSCAGSIHASGGSKSRSKRHQKQSGQQTRNPDHNGQRTGAATPCTGQKAKQGNAKWRQQQPNPSSNNQQQQMQQQMQQQKRGRNKKPGKWSNNIIDNPNSNHGGSSQQKTCDSSSSSALSSPTSSATTSATSSPTNSPTSYPRANGNRKRIEAALEWRREQELGRQNANFLVPPLRQYEQLEFDDKTVVQQLRRHIIDNHLLRVYGFPVDSVVHEGAIEIFKCMPHMSFAAALAETAQAVTVINYHDGLTNRAEEEVANSTDSGNSSPQSLDSESGGEWSGSECESSNSSSSSAGEAALGLELKYCHFVPVERSLSKPCARCKRHFLVDELTGQYLTHEECQYHSGKYQRYYDGVSHGRWTCCNEGEESSPGCCLGDRHVWSGSVVGVNGPYYDFVRTEHRGSGEDEPAVYALDCEMSYTGRGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITETDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVHNTLIDTSISFPHCNGFPYRRALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMELMLWRVNRELDPAWSWDD
Protein: Probable choline-phosphate cytidylyltransferase (EC 2.7.7.15) (CTP:phosphocholine cytidylyltransferase) (CCT) (CT) (Phosphorylcholine transferase) (O74975)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Choline kinase
- CTP-dependent diacylglycerol kinase 1
- Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.10
Sequence:
MGEEGIKINDTHKRRIDEVEPSEKEDNVERQTKKYNFEIDEPEEQEKKDEKEDDKEESPSKSLEEISQSVSPVEEEPRDVRFKELSTPFSYPINDPPEGRPVRVYADGVFDLFHIGHMRQLEQAKKVFPNVHLIVGLPNDQLTHRLKGLTVMNDKERAEALRHCKWVDEVLENAPWVITPEFLEEHKIDFVAHDDIPYASDDSGDIYLPVKKVGKFIPTKRTEGVSTSDLITRIIRDYDQYVMRNLARGVNRKELNVSLFKKNELDLRHHIKVLRDTLRNHWVSTTRDLKADIKSFLSMATTDYQLQKNPLHGSSEPSSPGPTGFLGGINRWMQRRSSSHYDLPRVGNEIAASSSSATEENH
Protein: Endoplasmic reticulum junction formation protein lunapark (Q7K2N0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU367073}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU367073}.
Interaction partners:
Sequence:
MGFVLSKLRKEKSTEAVLEGLQTQIQALEKYMINTEERKRRFVTNFVGFTIGAYIVGFGLWWYFYFPPTMQECFMYLVPLLLFPIVIIFLRRLFTWYFQRKLNKNGDKLTRLKEDKRKILEQVMDKETYKVAVNLLERFGDKKQLRISGLPTGSTPNRPQVERSPLTVAAVARTSSAGGQQQQQRSLAPYTSVYRNNNNNQNTSLNSSVISTHSLGQMTSASPQLRAVQELRRRSPFPIVDDRSRSAIDRIVDFIVGDSPKDRFGMICKACHAHNGMLPKEEYEYTTFRCAFCNVLNPARKKRPVAPRLSLEAPSDTANKRNDSSESESSDDDSDKEPSARRALLQKLPSGGADMDATAETEDLAMETETIETGSAAPSTAEVAASS
Protein: Caerin 1.1 (P86484)
Organism: Litoria peronii (Emerald spotted tree frog) (Hyla peronii)
Function: Antibacterial peptide with wide spectrum of activity. Active against the Gram-positive bacteria B.cereus (MIC=50 ug/ml), E.faecalis (MIC=25 ug/ml), L.lactis (MIC=1.5 ug/ml), L.innocua (MIC=25 ug/ml), S.aureus (MIC=3 ug/ml), S.epidermidis (MIC=12 ug/ml) and S.uberis (MIC=12 ug/ml), and against the Gram-negative bacteria E.coli (MIC=100 ug/ml) and P.multocida (MIC=25 ug/ml).
Subcellular location: Secreted {ECO:0000269|PubMed:19642086}.
Interaction partners:
Sequence:
GLLSVLGSVAKHVLPHVVPVIAEHL