wanglab/gogpt-training-data huggingface dataset:
Protein: Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Q8IDB6)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Exosome complex exonuclease RRP6
- Exosome complex component RRP45, putative
- Exosome complex component RRP4
- Exosome complex component CSL4, putative
- Exosome complex component RRP40, putative
- Exosome complex component RRP41
- Exosome complex component MTR3, putative
- ATP-dependent RNA helicase SUV3, putative
- Ribosomal RNA-processing protein 42
- ATP-dependent RNA helicase, putative
Sequence:
MTFLKLTNRKGERHVQKYFYKLNANNRINKIVREVYLRNDISCGIEKCNICENNKKKLLDGERSILILDLNTLIKYMDFLYDCDIDNILIPLSIYDYIKSFNKILYKKLRNLCYDVDEESIIEGSSSSSSFNHNKRFCVFVNTFCKFTYVEDNKDDTNGFNKELQEIIKIVIWLKHHNNKLNIKVISNNKLLQEDCYNNDIPCSTLFEYVNELMKGNDYKKKNKEGKKFNMDTLKMYFEEDILNEHNDSKADHTESTCDQKTYHTLNNLSLNSNNNNKRPLYEPHLSKSDMIQKLRENKIIKGVFSVICVNKLALVKFSDVDEIVIRGTKYMNRAIHNDVVAVEIIDEPNEDLYEEDYLEEQISPEEEEEEIEEEVEVEIEEVGEKVKIEINNMNKEKLQNSYIKNEDVKEKENVIDIYNKNNDIVQKDMINLYEKKMNITYDKQINENIYNNINNRHISEKKKLYGKVVGIISRCRKEYGGIIKEYSNNLNNIKKKLMFFKAFNNKIPYIMIKAQLEDELRNKRVIVTIDNWDIYSRNPLGRCISVLGNCDDIETETKLIYNEYNISTREFSENVYKCLPPNNWVIPDEEYEKRNDFRNVLTFSIDPPGCQDIDDALSVEFLQQDGNIEKNYIYRIGVHIADVSYFVKQNSPIDLEASKRCTTVYLINQRVDMLPKLLTTNLCSLVEGEERLTYSCIFCFNKDFDIIDISVKKCIIKSNKSFSYEQAQNVIDDKNDQSDTAKSLRLLNKIAKHLKQKWSNDGALELRGNTEVLFEFEANDFSKAKNLKPYVCYETNKLIEAFMLLANRSVARIIFQNFKAASVLRRHPPPKHEYLKELNDYLKTIQVFDFKYNTSKDLSHSINNINLKNDNILSNILKVMVTKCMNEAVFISGYNVHNNDMLRHYGLAADIYTFFTSPIRRYADIMVHRILNHIYQIEELDKKYLDIIYLNKQVALLNDKYRNARFASRASVDFFSYLYIKKIGNQITNAVITNLKKNGIQIFLIDYFTEGICYLKRKDGFLFDEKKKRFIKIDKYKNELFHLSFYDKIQVHMQVDNYDIKCQNHFIFIKKI
Protein: Uncharacterized protein (Q57XV1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPGYPTGLLLGCRMSSRPRVSWLSPALASHQQLDAGIAARHQVDRKSIKKSKRPFENYFRSEYRCSPSPSRFTLRPGGRVSSYDAVKLMTDPRRNWSPFWGRVVGNVRTQKKRQDVLQPAPQQFGEDSLDQTIQRFLELRFQWDRGDDILAPSLVPPSLYSLTEHCLPYACDEQQQQQTVSDCVELDGGGAHSSAFRARGRRKCLLVPRGNLGSSGVETIPSIVLDAARGPLVSSPTELSLNLRWKATNREATSVSEVLRLQQCVGHVPVMGMTARSLLLLLKAHATAEVENPPLAVALAIAAAEHYHEYTPTECLELLRCLRRVAFVKGLTQLSHSQVNVVSLYRDSRHSQMFFAGYIGDAAPFLVERVWSRLPEHAQRLCRRRLFLDFIDLLALAVEMNGWRFPCNLPNPASSATYASKYLFLRYTLQLDEAMMTEYVRCVADATFSAPQTELYTNVGGQQQNSRQLIASRCDPDDSETLFTPLITWLCVSFLARVTAEAVGDVLRHTEISLKQHMKLAKDYQSAAARGKSKLQRLKAERDLQQFLDSIALVRPRHHVYQCIGRRHPRKMRLRVIPLEAFPAISRHTGLPFGSASRHAHLSAERRCGSFEHDDWTFEAVVARSALARKHIERAKDALDWAAMMLTNCAVIARHIPTPAKRLEACGPKHTFVFPAASHLPSSIDAASNRLAWCEALVRSRVQEDIDSLFLHIPWCELEEQLQPFLDSEGKANGIESKEGTQRAGKVTTAGDDGTSLLDAYFPFDFLDNSGGTGDCRQVPPIEYDDAEHTKHPKTAQQDQNSLEALQVSIEKFQVTVAELIRAQEDYFLIL
Protein: C2H2-type domain-containing protein (H2L0N7)
Organism: Caenorhabditis elegans
Interaction partners:
- NR LBD domain-containing protein
Sequence:
MTEPSTSGAQDHDDYLVTLSSPQRQCTIRVVQPASALKRKLPTSSVPEFNPDSYGESIPENAPRPVCETCSVAWSTWAAYEFHMLQTHIIYRPFRCSGCRNLNFHTEDEGKHHLEHFHGGKPGSFQLIKQTDFAKENQLIECLENAKTTEQLGISKERLENGLKMIEKLQKIKFKAVKVHLPCCLRHEMISKHTETEKEAPPQEKSVTNAQKPGNPALLSLESRNYDYEQQDTVGI
Protein: ATP-dependent RNA helicase (EC 3.6.4.13) (Q381N9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ribosome biogenesis protein BOP1 homolog
- NLE domain-containing protein
- Pescadillo homolog
- Ribosomal protein L1p/L10e family
- RNA-binding protein, putative
- ATP-dependent RNA helicase
- Nucleolar GTP-binding protein 1
- Ribosome assembly factor mrt4
- Nucleolar complex protein 2
- rRNA processing protein, putative
Sequence:
MGIKGRRKRQREREAKAANGKAGLDNEYVEEGEEEVDSGADDVMVMGSGPFRPPVGPHGKLLIKKTELYNMQDTEYLDRLAEEHANRRTTHLRKTRSREGQKDTASETDKLLLHHFDNEEDFQTLFNTGGAKAGTRLSNITEVLDDEARVRRVRKKVETGARFNHPLIGVNENVVQALQQEGFCRMTPIQERVIPYALQGYDLLGQAQTGSGKTLAFCVPVLHSIIGLVSKRPNVTYSLMLSPTKELCVQTHDVLRGICQHISSDIAAFSVHLITGGTKVSEERRQLNSGVSIVVGTPGRIHDHVQHCSGWDLSRLRALVLDEADRMLADGFQRSLDAIVQRLPRSRQTYLFSATNSKSIGELARLSLSRKPLFITTTGSAPIPVQLGTEAFDSAVAAGCVDAASATFPPYCSYDDPDVDDQLKRGRASDTGGNEAGGDIKPIPDTLRQFCHITPVHERLLCLYAFVKRVARTSKAMVFCSTVASTIFHFQMLGSVGFHNEVIMLHGQMKHRQRVAAFQAFNEWTTGVLLCTDVAARGLDIPDVEWILQYDPPLDPTEYVHRIGRTARAGNVGNALLFLTPEEAGFVRYLSKFGISLEKYPMPAKLPPIQMKLEHVLQLDPIVAKSSVSAFRAHVGAYQSHLLQNIFNVHRLDLEGLARSFALSAVPSVSLPSSSVEEKQQEYVKGKLKSLNKRRMEAKRYYEAQKTKKQWTEDGQFVGMAFPKS
Protein: DmRNase-66B protein (Q24485)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQSQRFLFVAILACFLVTIKSTPLSDISDSDESTSVDEKTQKRPDDDSEFDGFPFREDDDSLQDSSREMSVQDHNWDVLIFTQQWPVTTCYHWREENPDQECSLPQKKEFWTIHGIWPTKLHQMGPNFCNNSANFDPSKLNPIEDRLETFWPDLKGMDSTEWLWKHEWQKHGTCAMLVEELDNELKYFEQGLTWREEYIMSRILDASDIHPDSNNTVAAINNAIVKALGKNPSIHCLYDGKHGISYLSEIRICFSKSLELIDCDGIKQGDAVPVGVPGGTIITNCHIGSLVHYPSLVPPLQRKSHWKLPLVNVYKLLQFLMWFTL
Protein: Protein ESMERALDA 1 (EC 2.4.1.-) (O-fucosyltransferase 17) (O-FucT-17) (O-fucosyltransferase family protein) (Q9ZVF7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Glycosyltransferase that plays a role in cell adhesion.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:27317803}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Probable pectin methyltransferase QUA2
- Galacturonosyltransferase 8
- Fucosyltransferase
- O-fucosyltransferase 23
- Probable pectinesterase/pectinesterase inhibitor 19
- Probable pectin methyltransferase QUA3
Sequence:
MLAKNRLPGSGHTTPSPPASPRRSPRYRHGRSKAAAGSRFPTVQPSRTLAHRLSWILLSVLLRRQGIFLFAPLIYISCMLLYMGTVSFDVVPIIQRRPPPGSVYKSPQVYAKLRPEMDADNSTADAITTIWKHSYKGGEWKPYVNKSTGDLPESNGYIYVEANGGLNQQRTSICNAVAVAGYLNATLVIPNFHYHSIWRDPSKFGDIYDEEFFVSTLSNDVRVVDTIPEYLMERFDHNMTNVYNFRVKAWSPIQYYRDSILPKLLEEKIIRISPFANRLSFDAPQAVQRLRCLANYEALKFSKTILTLGETLVKRMKEQSANHGAKYVSVHLRFEEDMVAFSCCIFDGGNQEKQDMIAARERGWKGKFTKPGRVIRPGAIRQNGKCPLTPLEVGLMLRGMGFNKSTYIFLASGEIYDANRTMAPLLEMFPNLQTKEMLASEEELAPYKNFSSRMAAIDYTVCLHSEVFVTTQGGNFPHFLMGHRRYMFGGHSKTIRPDKRKLAILFDNPNIGWRSFKRQMLNMRSHSDSKGFELKRPNDSIYTFPCPDCMSRRNKTTTPESRPPPAT
Protein: 1,3-beta-glucanosyltransferase (EC 2.4.1.-) (G8B600)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU361209}; Lipid-anchor, GPI-anchor {ECO:0000256|RuleBase:RU361209}. Membrane {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004589}.
Interaction partners:
Sequence:
MLFKSLLSTTLLAATSLIGTAAAAEELPTVEIVGNKFFYSNNGSQFFMRGIAYQQNNLNSSDSFKDPLADPETCKRDIPYLAAVNTNVIRVYALDIEADHTECMEALQEAGIYIIADLSQPDESINRKDPQWTLDLFQRYTGVVDAFHNYTNVLGFFAGNEVTNDDTNTDASAFVKAAIRDTKAYMKAKDYRTIPVGYSSSDHAAIRVALADYFACGDEDERADFFGINNYEWCGKSSFESSGYATATDDYKDLGIPIFFSEYGCNKVSPRLFTEVGTIFGDDMTDVWSGGIVYMYFEEENNFGLVSIEDGKVSTLEDYNNYKSEILKISPSSAQASAESASGTGVTSCPTSTSVWAAATDLPPTPDKEVCDCMANSLKCVVSDKVDSDDYADMYSYVCAKIDCGGISSNGTTGKYGAYSPCSAKDKLSFVLNLYYEDQNENESACSFDGSGSLKKSATTASSCSAYLKSAGSSGLGTVEGSVRTDTSQESDTNGGGKQNSGSGSSSGSGSGSGSSSSSDSSSSGSSTSSGKSNDGVAGGLIGVSALTKLSAVVISMVLGFSFILI
Protein: AT2G34560 protein (P-loop containing nucleoside triphosphate hydrolases superfamily protein) (B9DGC0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 6 homolog
- Transducin/WD40 repeat-like superfamily protein
- Ubiquitin-fold modifier 1
- AT5g37360/MNJ8_150
- Stress response protein
- 26S proteasome non-ATPase regulatory subunit 11 homolog
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial
- 26S proteasome regulatory subunit RPN13
- Proteasome subunit beta type-6
Sequence:
MATDEPSQTRWSFLEFKTFYDAKFGRKKLPEEDVSNKDQPEDGSSNGNNGDVNNNSSPVTNQDGNTALANGNVIREKPKKSMFPPFESAETRTLAESLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRSEHEASRRLKTELLIQMDGLQKTNELVFVLAATNLPWELDAAMLRRLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQPLRRTLAILEDREDVVPEDELPKIGPILPEDIDRALSNTRPSAHLHAHLYDKFNDDYGSQILK
Protein: Unconventional prefoldin RPB5 interactor-like protein (Q9W148)
Organism: Drosophila melanogaster (Fruit fly)
Function: Inhibits the activity of serine/threonine-protein phosphatases flw/PP1beta9C and Pp1-87B. Required for germ line cell viability and differentiation, normal transcriptional activity and maintenance of DNA integrity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18412953}. Chromosome {ECO:0000269|PubMed:18412953}. Nucleus {ECO:0000269|PubMed:18412953}. Note=In primary spermatocytes and maturing spermatids, found throughout the cytoplasm with a distinctive concentration in speckles. In the embryo, primarily cytoplasmic with some protein in speckles in both the nucleus and cytoplasm. In salivary glands, predominantly cytoplasmic with a mild perinuclear accumulation. Also detected on salivary gland polytene chromosomes where it is associated with regions of active transcription. {ECO:0000269|PubMed:18412953}.
Interaction partners:
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- GEO12025p1
- Probable prefoldin subunit 2
- Probable prefoldin subunit 6
- RuvB-like helicase 1
- RuvB-like helicase 2
- RNA polymerase II-associated protein 3
- PIH1 domain containing 1, isoform D
Sequence:
MDRREDALLQALQTNASETERWEAFKRDNESTIRNLDKFAKNLSVEVMVPIGRKALMPGELIHTNELLVGHYEGYFSACSSHKAKEICQYRLKLAEEQLKKLAVENDLWQKKLHTPFAEGAVPSGDQVEIVEDFNEESHNKWLAEHRKRMRQQKQKERLEREAEPVKKDNEVLRKLEEREMMEELGLDPDNIDEDQLHDMLNQEPLKSTNESSPKSLTQEEEDELWKKLEAEEQNEADELSSEAEESLKTTDNLVRQLMSGETETPSSKKRTAGTNRNVEIQDPISEDDGDDDDEGDQEEEVRTIREQMSLLPNEDREPFLRAQLHVLKAKMRKIQKVNFISDELIHLMNVVVMLEDDLQDLVFEQELEASEEEEEVVENNHLPDEPSKELSTVSESSTNKRRISFALDDEKLEFRREETVAEMLPNAKKNSRDIIKLNAPLKPAGDPQPASIKTKRQTTQDILQKVERNIEFVKENQSVQDFDLLNRIMEESTGLINTLHISFTHSGAIPSPSSDQSDGIPGKPSDFYVRYEKDRARPNDSFPIYVNGFEGEEHVKVPIMSEAARGSAYEDPRSQFSKPNSSEICFTHSGSITPTSNDQSDDIPGNPFDFYEKYEKDRAKFSKSNSSEGDATDPESATKSILRNKSAVDLEPHNVNQQPKKGRKVRNQKKKERTLDDDLRDMSAYQKVMHDLVEKEPTAPEPLPPGKFIDSHAPKKRVSRFKEQRALNKT
Protein: Helix-loop-helix protein 2 (HEN-2) (Class A basic helix-loop-helix protein 34) (bHLHa34) (Nescient helix loop helix 2) (NSCL-2) (Q02577)
Organism: Homo sapiens (Human)
Function: Transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3'. Involved in regulating energy expenditure, body mass, voluntary physical activity, mating behavior and reproductive longevity, acting through the hypothalamic-pituitary-gonadal axis. Acts as a transcriptional activator of target genes, including NDN, PCSK1, MC4R (By similarity). Is also a transcriptional activator of KISS1. May act centrally to regulate function of both white and brown adipose tissue. Together with NHLH1, required to maintain migration and survival of cells in the anterior extramural migration stream (aes), which forms the precerebellar nuclei. Also, in concert with NHLH1, may determine fate of gonadotropin releasing hormone-1 (GnRH-1) neurons.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Protein BEX1
- Protein BEX2
- LIM domain-binding protein 2
- LIM domain-binding protein 1
- Rhombotin-2
Sequence:
MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
Protein: Transient-receptor-potential-like protein (P48994)
Organism: Drosophila melanogaster (Fruit fly)
Function: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Required for vision in the dark and in dim light. Binds calmodulin. Trp and trpl act together in the light response, although it is unclear whether as heteromultimers or distinct units. Also forms a functional cation channel with Trpgamma. Activated by fatty acids, metabolic stress, inositols and GTP-binding proteins.
Subcellular location: Membrane {ECO:0000269|PubMed:11931743, ECO:0000269|PubMed:9494079}; Multi-pass membrane protein {ECO:0000269|PubMed:11931743, ECO:0000269|PubMed:9494079}. Cell projection, rhabdomere membrane {ECO:0000269|PubMed:11931743, ECO:0000269|PubMed:1314616}; Multi-pass membrane protein {ECO:0000305}. Note=In the dark, there is 20 fold more rhabdomeral trpl protein forming plasma membrane channels than in the light. In the light, the protein translocates to an intracellular compartment. Protein levels remain unchanged in light and dark conditions.
Interaction partners:
- Inactivation-no-after-potential D protein
- Opsin Rh1
- Transient receptor potential protein
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- Neither inactivation nor afterpotential protein C
- Protein kinase C, eye isozyme
- Phosrestin-1
- G protein alpha q subunit subunit alpha)
- Calmodulin
- Transient receptor potential cation channel subfamily A member 1
Sequence:
MGRKKKLPTGVSSGVSHASSAPKSVGGCCVPLGLPQPLLLEEKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDINTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYDPQMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKCYVLPGGEADWGSHGDSCMKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPSVKWVIRIFRKSSKTIDRQRSKKRKEQEQFSEYDNIMRSLVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLEIFENSGMDVSSANKKERQPRPRRIKVWERRLMKGFQVAPVQNGCELDAFGNVNGQGEMQEIKVESIPSKPAKETAKERFQRVARTVLLQSTTHKWNVVLRAAKDSQIGRCTKNERKSLQNLGRAIEEAKRLIMLNPGCPSGRESPIRIEFEDEKTSTLLELLNQISAEISDSEKPKIRPIWRPPLKTVPARAMAANNTRSLTAPELKISRKSSPAPTPTPTPGVSHTALSQFRNRELPLCPSKLIANSAPSAPTAPPKKSAPTAPTPTYKPTTHAPFSVEGGNRENTRASDGVRSDNSNFDIHVVDLDEKGGHLGRDNVSDISSIASTSPQRPKHRN
Protein: ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase) (D4AAT7)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03157}.
Interaction partners:
- NAD
- Enhancer of mRNA-decapping protein 3
Sequence:
MAVCPYGAAAVVMALLSAAIAFHCSPLLAVLQRALSLHTAHATKDMDNLFQLVRNIVPALTSKKHKGQDGRIGIVGGCQEYTGAPYFAGISALKVGADLTHVFCAREAAPVIKSYSPELIVHPVLDSSDAVEEVEKWLPRLHALVVGPGLGRDDLLLNNVRGILESTKARDIPVVIDADGLWLIAQRPALVHGYQKAVLTPNHVEFSRLWDAVLSSPMDTSNHSGSVLKLSQALGNITIVQKGEQDLISNGQQVLVCNQEGSSRRCGGQGDLLSGSLGVMAHWALRAGPEKTNGSSPLLVAAWGACTLTRECNHLAFQKYGRSTTTTDMIAEVGAAFSKLFTT
Protein: Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOD) (DHODase) (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) (P32747)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: In the de novo pyrimidine biosynthesis pathway, catalyzes the stereospecific oxidation of (S)-dihydroorotate to orotate with reduction of flavin and the transfer of electrons to ubiquinone, which is part of the repiratory chain. Does not use fumarate and NAD as electron acceptors.
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable dihydroorotase
- Orotate phosphoribosyltransferase
- Orotidine 5'-phosphate decarboxylase
- Protein transport protein got1
- NADH-cytochrome b5 reductase 1
- Uncharacterized FAD-binding protein C17H9.12c
- Carbamoyl phosphate synthase arginine-specific large chain, mitochondrial
- Multifunctional tryptophan biosynthesis protein
- Adenylosuccinate synthetase
- Multifunctional protein ura1
Sequence:
MYQRSLFRGVAQGLKRSSVRFQSTSSGSSNGNFFLRHWKLLSVIGSFTAGVAIYDMSDVRSFIHGRIEMPLFHAFTTPEFSHRVAILAASWGITPKDRVADDPSLAVEVWGKKFCNPIGLAAGFDKQADAISGLLNFGFSYLEIGSVTPKPQPGNPKPRYFRLKPDLSVINRYGFNSIGHDAILAKIQKRVRKYIAKTSPQLLKQFDANPASCTDPAVLGVPRSLIPNKFLGINLGKNKNGNEIEDYVEGVRTFGNFADILVINVSSPNTPGLRNLQKKSALSTLLTAVVSERNKLNSPHPPVLVKIAPDLNEEELTDIADVLKKCKIDGVIVGNTTVQRPKTLKSTSHVEETGGLSGPPLKPIALNTLRTLRKHLSSDIPIIGCGGISSGKDAIEYARAGATMVQVYTALGYDGPVIAHKIKQEILAELKGKRWVDIIGKEE
Protein: CRS2-associated factor 1, chloroplastic (Chloroplastic group IIA intron splicing facilitator CRS2-associated factor 1) (Q9SL79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the splicing of group IIB introns in chloroplasts. Forms splicing particles with CRS2. Interacts with RNA and confers intron specificity of the splicing particles.
Subcellular location: Plastid, chloroplast stroma {ECO:0000305}.
Interaction partners:
Sequence:
MSLKLNTPFPIFAPSLFPNHNPRAPSEIRFSRWGNANAERFEQRRRSQEELEAEIRRDRRFDAATKIVHTHDSEAAAAEPKTSPFRSRGTPSLPSARSIPGRRSKYSKPDSGPNRPKNKPRVPDSPPQLDAKPEVKLSEDGLTYVINGAPFEFKYSYTETPKVKPLKLREPAYAPFGPTTMGRPWTGRAPLPQSQKTPREFDSFRLPPVGKKGLKPVQKPGPFRPGVGPRYVYSKEEILGEPLTKEEVRELVTSCLKTTRQLNMGRDGLTHNMLNNIHDLWKRRRVCKIKCKGVCTVDMDNVCEQLEEKIGGKVIYRRGGVLFLFRGRNYNHRTRPRFPLMLWKPVAPVYPRLIQQVPEGLTRQEATNMRRKGRELMPICKLGKNGVYCDLVKNVKEAFEVCELVRIDCQGMKGSDFRKIGAKLKDLVPCVLVSFENEQILIWRGREWKSSLTTPDKKGDILEDIEVDTALPEDDEPSVSPNQSQTMTQNPPLDSMELQNDPDGHDLSPSTVDSSEMEGTINSLQSWSTKDVTEPTVDSFLRDLEEPEDEPETSEEISKQSIERVLILMKQAVESGTALVLDAADLDADTVFSKAVAFSSVASPGPVFQHGLRKQPTVKKQESQEFGYGDLEAKSSNVVVSRNASKSSNVVVFGKREVAERGEREEKEEGSKKKMDEFAEDYREVMPHGTLKVDELAKLLA
Protein: Transmembrane protein 59-like (A8WG81)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004614}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004614}.
Interaction partners:
- Trafficking regulator of GLUT4
- DnaJ homolog subfamily C member 10
- Stress-induced-phosphoprotein 1
- ClpB homolog, mitochondrial AAA ATPase chaperonin.
Sequence:
MLQFGGRVRGVPALVSLILVALAAASSDLFDNQLGDINYCKKQCQMSIKNKSPAKDSIMNACHRGCRLYSICQFVNGNTGINTSKEECQGACQEAYSKLLEQEACSTGCASQPAEPEIKRRKLKALTNRPKPISVMEAVSSWCNDIVSSAQSFISSTWTFYLQADDGKVVVFQSQPEIEYSLPELQAPRSNVVDKPWPQVNSHTQRPHTGGRSHRERNAAKPGVKGKNVSQHAEDPAAEHDFLGCMSRRSGLPRWILAACLFLSIMVMLWLSCASLVTAPEQHIKTQLSINGDKEFMDDAQKVNPYHLTPVIAMTIAQSEESKEAGPLPVKVDLSKTSL
Protein: Ribosomal RNA-processing protein 15 (Q9UTD7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Constituent of pre-60S ribosomal particles. Required for large subunit rRNA maturation (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Brix domain-containing protein C1B9.03c
- Brix domain-containing protein C4F8.04
- Uncharacterized RNA-binding protein C1827.05c
- Ribosomal RNA-processing protein 1 homolog
- ATP-dependent RNA helicase dbp8
- Ribosome biogenesis protein brx1
- Protein mak16
- Ribosome biogenesis protein rlp24
- Probable rRNA-processing protein ebp2
- Ribosome biogenesis protein nsa1
Sequence:
MAKSQRSQIKNEDISFVSQEDDSSKKFVKDDSENSEEELEDLNSEDEFYQSNSSEDEIEEEVQESTIADDIADILNQQVTQTDEQDTPVLSLSKKSKKALRKSNAEKKDSKLRTSRRRERLRKEMVGRVTSVVAVNAETAKALFTHERELRRIARRGVVQLFNAVRTAQLQSSLNRENISGGRTAREQKVKELSKASFLDLIKSQ
Protein: Endo-beta-1,4-glucanase celB (Endoglucanase celB) (EC 3.2.1.4) (Carboxymethylcellulase celB) (Cellulase B) (Q2TX26)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- cellulase
- Probable endo-beta-1,4-glucanase B
- Probable beta-glucosidase A
- Glucanase
- Probable 1,4-beta-D-glucan cellobiohydrolase A
- Glucanase
- Carbohydrate binding X2 domain-containing protein
- Chromo shadow domain-containing protein
- Uncharacterized protein
- beta-glucosidase
Sequence:
MIWTLAPFVALLPLVTAQQVGTTADAHPRLTTYKCTSQNGCTRQNTSVVLDAATHFIHKKGTQTSCTNSNGLDTAICPDKQTCADNCVVDGITDYASYGVQTKNDTLTLQQYLQTGNATKSLSPRVYLLAEDGENYSMLKLLNQEFTFDVDASTLVCGMNGALYLSEMEASGGKSSLNQAGAKYGTGYCDAQCYTTPWINGEGNTESVGSCCQEMDIWEANARATGLTPHPCNTTGLYECSGSGCGDSGVCDKAGCGFNPYGLGAKDYYGYGLKVNTNETFTVVTQFLTNDNTTSGQLSEIRRLYIQNGQVIQNAAVTSGGKTVDSITKDFCSGEGSAFNRLGGLEEMGHALGRGMVLALSIWNDAGSFMQWLDGGSAGPCNATEGNPALIEKLYPDTHVKFSKIRWGDIGSTYRH
Protein: Mating-type switching protein swi2 (Q10668)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for normal mating-type switching.
Interaction partners:
- Mating-type switching protein swi5
- DNA repair protein rhp51
Sequence:
MNVNKKQESIPVNTGSESISSNDNERFEQGKGVGSNLGSHFFEPVEYYYSDGKPMNQTEASQMKGTFSRDFSLNEMNNEFITDSFFCTTTPDPKTESPSFVKYNAHCDDHPEISGHVSSNDKDFAYFEDKSENQPLVTLPNENNQVIEPLSSQSCKSQLSTQNYSESDFGWNQLCDLDPIFKSLAFTDDTNLFPAFADSEAALIMLKKREMTRVKHRAGRPRKYSYVNKDLNFEEGLPRRRGRPTGWRKYPEKEEIYPTLSPRIKKPRKVFDAVVIPVTIKPSIYTEPSLPHHIDWNNGCSEEFDFEPSREDEDFPDLTSDSTGQDPLSSEPTIFDISPLPSDMEPTFSENSLITINKMAIEERKQSRRLEQPLAESQHQEDLLNPYGVDQDFDETCINESEQQATHIPNSSIKFNYDYTPPKSATSHKHKRVDLLASRKENVWTGLYGKVQTEMVSNRGEAVLNENNSKNRTNVTKPNSYKNSVLSIGNNHSNHSNIIKPNTYKNTILSNENNTPNYSNVCLSTSLINRSLPSLKSTMHPGVNKDLITRPFKNVNKMSVRKALIKPFHPPISKISRTRLTVSSPERLYCAKPISMATAPSETDSKLINRIRNLELEIGGLKEQLSVVELALDTDKNSKQIQVVERKIQNWRKSAQLAVEVLFPVFSLKFTTMLQEVPQSVLRTSANDLRTKPCSIGTYLEQLQIPFHLLQYNSETESWDLE
Protein: Nucleoporin 43 (Nucleoporin Nup43) (Q6NYF4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDCISAKYISQKISKTRWRPVSAASLQQPEVFATGSWDNENNKVSIWSVGDRGGSTLDGDLDEEPQLLCDSQHEGDVMDLQFLDQDRLVSASSSGAVSIFKLQSDCQALSLAHVWERAHRCSCNNAPCTAIVCRSPEIVSVGEDGRVILYKADQAEVTRVIENADSSTIHAVTFLRTTEVLTVNSIGQLKMWDFRQQSDSPAQILSLTGDRMPLHCVDKHPNQQHIVATGGQDGMLCIWDVRQGNTPFSLTEAHSAEMWEVHFHPSNPNHLFTCSEDGSLLHWESTSGSDVSTLLQKGWNSRVVSQSALSLAGENDSAVSAWLAGDSSKSRLEATHMLPSQTLSVNSLDVLEQCLVCGTDGEALYIHRQVPV
Protein: Large ribosomal subunit protein bL19 (50S ribosomal protein L19) (P0A7K6)
Organism: Escherichia coli (strain K12)
Function: This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8. In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA. The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation.
Interaction partners:
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein bL21
- Small ribosomal subunit protein uS13
- Elongation factor Tu 1
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS10
- Alternative ribosome-rescue factor A
- Small ribosomal subunit protein bS6
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein bL9
Sequence:
MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN