wanglab/gogpt-training-data huggingface dataset:
Protein: Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (P00184)
Organism: Mus musculus (Mouse)
Function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions. Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation. Catalyzes the epoxidation of double bonds of certain PUFA. Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system. Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer. May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues. Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid. May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P00185}; Peripheral membrane protein {ECO:0000250|UniProtKB:P00185}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:P00185}; Peripheral membrane protein {ECO:0000250|UniProtKB:P00185}. Microsome membrane {ECO:0000250|UniProtKB:P00185}; Peripheral membrane protein {ECO:0000250|UniProtKB:P00185}. Cytoplasm {ECO:0000250|UniProtKB:P00185}.
Interaction partners:
- UDP-glucuronosyltransferase 1A1
- UDP-glucuronosyltransferase
- Epoxide hydrolase 1
- UDP-glucuronosyltransferase 1A6
- UDP-glucuronosyltransferase 2A3
- UDP-glucuronosyltransferase
- UDP-glucuronosyltransferase
- UDP-glucuronosyltransferase
- UDP-glucuronosyltransferase
- Catechol O-methyltransferase
Sequence:
MPSMYGLPAFVSATELLLAVTVFCLGFWVVRATRTWVPKGLKTPPGPWGLPFIGHMLTVGKNPHLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSCYLEEHVSKEANYLVSKLQKVMAEVGHFDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPVLRYLPNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRKLDENANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFKVSPGEKVDMTPTYGLTLKHARCEHFQVQMRSSGPQHLQA
Protein: Testican-1 (Protein SPOCK) (Q08629)
Organism: Homo sapiens (Human)
Function: May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- SPARC
- Matrix metalloproteinase-16
- Follistatin
- Thyroglobulin
Sequence:
MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRFRDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAVTEDDEDEDDDKEDEVGYIW
Protein: RH25219p (Q8IP63)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPYANQPSVQITELTDDNVKFVLEDTELSVANSLRRVFIAETPTLAIDWVQLEANSTVLSDEFLAHRIGLIPLISDDVVERLQYTRKVQRGTDAPRDHRRSQVEQCQGPAGDVPQPG
Protein: Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5) (GABAAR subunit alpha-5) (P31644)
Organism: Homo sapiens (Human)
Function: Ligand-gated chloride channel subunit which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. May be involved in GABA-A receptor assembly, and GABA-A receptor immobilization and accumulation by gephyrin at the synapse.
Subcellular location: Postsynaptic cell membrane {ECO:0000269|PubMed:31056671}; Multi-pass membrane protein {ECO:0000269|PubMed:30140029}. Cell membrane {ECO:0000269|PubMed:31056671}; Multi-pass membrane protein {ECO:0000269|PubMed:30140029}.
Interaction partners:
- Trafficking kinesin-binding protein 2
- Inactive phospholipase C-like protein 1
- Vesicle-fusing ATPase
- Huntingtin-associated protein 1
- Sodium- and chloride-dependent GABA transporter 1
- Gamma-aminobutyric acid receptor subunit alpha-3
- Gamma-aminobutyric acid type B receptor subunit 1
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid receptor subunit beta-1
- Sodium- and chloride-dependent GABA transporter 2
Sequence:
MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
Protein: Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1) (O76021)
Organism: Homo sapiens (Human)
Function: Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:11790298, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:18678645, ECO:0000269|PubMed:22419112}. Note=Colocalizes with ING1 in the nucleolus after UV stress. {ECO:0000269|PubMed:22419112}.
Interaction partners:
- ATP-dependent RNA helicase DDX18
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- Ribosome biogenesis protein BOP1
- Probable rRNA-processing protein EBP2
- Nucleolar complex protein 2 homolog
- Ribosome biogenesis protein WDR12
- Bystin
- Ribosome biogenesis protein BRX1 homolog
- Nucleolar protein 58
- mRNA turnover protein 4 homolog
Sequence:
MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYGLLLNENESLFLMVVLWKIPSKELRVRLTLPHSIRSDSEDICLFTKDEPNSTPEKTEQFYRKLLNKHGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIGRHFYQRKKVPVSVNLLSKNLSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST
Protein: piRNA biogenesis factor prde-1 (piRNA silencing defective protein 1) (O17828)
Organism: Caenorhabditis elegans
Function: Nuclear factor required for the production of piwi-interacting RNA (piRNA) precursors. Specifically required for piRNAs produced from loci associated with the Ruby motif. Promotes binding of the transcription factor snpc-4 at piRNA genomic clusters. Required for normal fertility.
Subcellular location: Nucleus {ECO:0000269|PubMed:24696457, ECO:0000269|PubMed:25373775}. Chromosome {ECO:0000269|PubMed:24696457}. Note=Concentrated in nuclear foci of pachytene germ cells (PubMed:24696457, PubMed:25373775). Colocalizes with snpc-4 in nuclear foci in a mutually dependent fashion (PubMed:25373775). {ECO:0000269|PubMed:24696457, ECO:0000269|PubMed:25373775}.
Interaction partners:
- Twenty One u-rna
- Twenty One u-rna
- snRNA-activating protein complex subunit 4 homolog
- K Homology domain-containing protein
- Ubiquitin-like protease family profile domain-containing protein
- Schlafen-like protein 2
- Schlafen-like protein 1
- SNAPc homolog
- Embryonic developmental protein tofu-6
- 3'-5' exoribonuclease parn-1
Sequence:
MNRNRKGHDLENIEHRFTDEDLAGLKEQKLFNGKWIILEKKEKRGAAYCYLVCDKPCKKFGILYLEIGEDNVTTIANQVDFYHQQSSLGYSHRFSALIDAGIINNHVFFMVVRIRAGPTLHDLLKCLSSDKMSVTTASFLAVDMISAIEILSASGWVLRNFDSKQWMLDIKTRQFYLADATDITVSSDKRHRAIDEIHLRTAESIDLHWKTGDLIYAPRSFVDRDQSHRMTELDMMEMMLYVLYDWTHGKLPWKSSKSRERIMEMKELFIENLQKEPEETNKVEQQIDVDVWFDIALRNFAKHLKVAKEEQEKLEKLPVRGGAWCPKGPRAGAQISTVNYRGIIDDFYKIVCSGRPAWALHWRDVMLDWDRKLENTPETSKMFEAYEKHQRSLEISEEWERLQATREHYTVMKNHTETEMAKNQAAIVEYLMPEEEAKEEPIDKKKDPEEEAAAAVVGKKRRGRKPKKKDDPKMELKDEVKDLKDFVVEESTSASSSAPKKRPCCSSGSPLKSSGGRRRGCEIRRK
Protein: Forkhead box B1b (Forkhead box protein B1b) (Forkhead-5) (Foxb1.1 protein) (O93312)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
- Gig2-like protein DreG
- Hairy-related 3.
Sequence:
MPRPGRNTYSDQKPPYSYISLTAMAIQSCPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVMISSEHLQKPSDAAHYLQQQAKLRMTALGTHLPQMTSYNLSVTQPSTFKHPFAIENIIARDYKMPGSLAFSAMHSMSTGYQIHNQLTTAWPHMYSSNVIDAEYAAYGVPLKSLSHGAQSLPAIPVPIKPAPASVPSIPALHAHLPAFLSGSPQSLSPASPSQSNPATPSPTSLLHSVAVHCQEVT
Protein: Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4] (Q12836)
Organism: Homo sapiens (Human)
Function: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor.
Subcellular location: [Processed zona pellucida sperm-binding protein 4]: Zona pellucida {ECO:0000250|UniProtKB:Q00193}.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q00193}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Zona pellucida sperm-binding protein 3
- Zona pellucida sperm-binding protein 2
- Zona pellucida sperm-binding protein 1
- Oviduct-specific glycoprotein
- Growth/differentiation factor 9
- Factor in the germline alpha
- Hyaluronidase PH-20
Sequence:
MWLLRCVLLCVSLSLAVSGQHKPEAPDYSSVLHCGPWSFQFAVNLNQEATSPPVLIAWDNQGLLHELQNDSDCGTWIRKGPGSSVVLEATYSSCYVTEWDSHYIMPVGVEGAGAAEHKVVTERKLLKCPMDLLARDAPDTDWCDSIPARDRLPCAPSPISRGDCEGLGCCYSSEEVNSCYYGNTVTLHCTREGHFSIAVSRNVTSPPLLLDSVRLALRNDSACNPVMATQAFVLFQFPFTSCGTTRQITGDRAVYENELVATRDVKNGSRGSVTRDSIFRLHVSCSYSVSSNSLPINVQVFTLPPPFPETQPGPLTLELQIAKDKNYGSYYGVGDYPVVKLLRDPIYVEVSILHRTDPYLGLLLQQCWATPSTDPLSQPQWPILVKGCPYIGDNYQTQLIPVQKALDLPFPSHHQRFSIFTFSFVNPTVEKQALRGPVHLHCSVSVCQPAETPSCVVTCPDLSRRRNFDNSSQNTTASVSSKGPMILLQATKDPPEKLRVPVDSKVLWVAGLSGTLILGALLVSYLAVKKQKSCPDQMCQ
Protein: F-box/LRR-repeat protein At1g67190 (Q9ZW88)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F-box protein At5g52880
- F-box/kelch-repeat protein At3g24760
- F-box/kelch-repeat protein At2g24250
- F-box/kelch-repeat protein At1g64840
- F-box protein At4g27050
- Putative F-box protein At1g47730
- F-box protein At1g30790
- F-box/kelch-repeat protein At3g04660
- F-box/LRR-repeat protein At3g03360
- F-box protein SKIP19
Sequence:
MDYLPVEVIGNILSRLGGARDVVIASATCRKWREACRKHLQTLSFNSADWPFYRDLTTNRLEILITQTIFQTMGLQGLSIMMDDANKFSAATVIAWLMYTRDTLRRLSYNVRTTPNVNILEICGRQKLEALVLAHNSITGVEPSFQRFPCLKSLSLSYVSISALDLNLLLSACPMIESLELVSLEIAMSDAQVTIELSSPTLKSVYFDGISLDKFILEADSIEFLHMKDCVLELFELIGNGTLKHFKLDDVSVIHLDIMETSESLEVVDVNHFTMVWPKFYQMISRSQKLKKLRLWDVVFDDDDEIIDVESIAAGFSHLTHLSLSYDLKDGAAHYSLQGTTQLENVTVLELGWTVINDVFSIWVEELLRRCPNLKKLIIYGVVSETKTQGDCQILATFTWSIVQLMRKYIHVEVQFEYE
Protein: Transcription initiation factor TFIID subunit 15b (TBP-associated factor 15b) (AtTAF15b) (Q94KD0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- RanBP2-type zinc finger protein At1g67325
- Cysteine/Histidine-rich C1 domain family protein
- RNA-binding protein-like protein
- Transcription initiation factor TFIID subunit 12b
- Transcription initiation factor TFIID subunit 4
- Transcription initiation factor TFIID subunit 4b
- Transcription initiation factor TFIID subunit 5
- Ran BP2/NZF zinc finger-like superfamily protein
- Zinc ion binding protein
- Protein MODIFIER OF SNC1 11
Sequence:
MAGMYNQDGGGGAPIPSYGGDGYGGGGGYGGGDAGYGGRGASGGGSYGGRGGYGGGGGRGNRGGGGGGYQGGDRGGRGSGGGGRDGDWRCPNPSCGNVNFARRVECNKCGALAPSGTSSGANDRGGGGYSRGGGDSDRGGGRGGRNDSGRSYESSRYDGGSRSGGSYGSGSQRENGSYGQAPPPAAAIPSYDGSGSYPPPTGYGMEAVPPPTSYSGGPPSYGGPRGGYGSDAPSTGGRGGRSGGYDGGSAPRRQEASYEDAATEKVKQCDADCDDNCDNARIYISNLPPDVTTDELKDLFGGIGQVGRIKQKRGYKDQWPYNIKIYTDEKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKISVTMAEKSAPRAPTFDQRGGGRGGGGGGYGGGGGDRRRDNYSSGPDRNHHGGNRSRPY
Protein: Las1-like (Q57YI3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop domain-containing protein
- SUMO1/Ulp2, putative
- Guanine nucleotide-binding protein subunit beta-like protein
- Ribosome biogenesis protein BOP1 homolog
- rRNA processing protein, putative
- Pescadillo homolog
- Peter pan protein, putative
- NLE domain-containing protein
- Ribosome assembly factor mrt4
- Uncharacterized protein
Sequence:
MEHERGSGLTLAPMKKKRGQHQQHAIPGSQKRVTGTRIKRGLDELYNLDAVPQQQSQESQPSPGRVSKCNDRGKGKSSKASSTAENPLMRSAVQGISTNGEKTAVSVAQRKEDDGPIVATAIIKMADTSEYCGSSPPTVFGYNWEEWKSVKQHLFNPTETAGSAAARRKALDHIELVWKARAREGRPLPSYVESTAMLLEAVSLDESNKMSSIAITALYGAVISRAVHVMTGEFARGADDTYRKRAQAIGFPEEAVEVRQRVSHGALPLLTELRWVCGLVLQFLFHNYWLEQERHLHCMEQEEKEAEVEVEKVNKNTRDAHKVVSNHATVEEMRWLLDALSDDCEEDEDTPGGDSCEECTNDGFHDADTIRVGDWTLS
Protein: Outer dense fiber protein 1 (Protein RT7) (RTS 5/1) (P21769)
Organism: Rattus norvegicus (Rat)
Function: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.
Subcellular location: Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q61999}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q61999}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q61999}. Note=Localizes to the manchette in elongating spermatids and to the sperm flagellum. {ECO:0000250|UniProtKB:Q61999}.
Interaction partners:
- Sperm-associated antigen 4 protein
- Spermatid nuclear transition protein 1
- Ornithine decarboxylase antizyme 3
- A-kinase anchoring protein 3
- Coiled-coil domain containing 42
- Sad1 and UNC84 domain containing 5
- Outer dense fiber protein 4
- Spermatogenesis-associated protein 6
- A-kinase anchor protein 4
Sequence:
MAALSCLLDSVRRDIKKVDRELRQLRCIDEISSRCLCDLYMHPYCCCDLHPYPYCLCYSKRSRSCGLCDLYYPCCLCDYKLYCLRPSLRSLERLRRTTNRILASSCCSSNILGSVNVCGFEPDQVKVRVKDGKVCVSAERENRYDCLGSKKYSYMNICKEFSLPPCVDEKDVTYSYGLGSCVKIESPCYPCTSPCNPCNPCSPCSPCGPCGPCGPCGPCGPCGPCDPCNPCYPCGSRFSCRKMIL
Protein: Uncharacterized protein AN7484 (Q5AW46)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Involved in osmoadaptation.
Interaction partners:
Sequence:
MAGFASANLLERVPEDEVLPAEFTVKAPPETDIWAKPPSTERFNAPILYKSIPLDTFKRARVAFSANWSQKYDQGGLIIVLNGNSGDRKWVKTGIEFTHDKPHLSTVAKDRWADWSLLPVPSGGTGATLEVVREPDDSLWIYLIQGVQKSPIREVTWVFAEEDVRDAWIGVYAARPSSAGGDLVVNFASLIIEVTDSTTK
Protein: Auxin-responsive protein IAA13 (Indoleacetic acid-induced protein 13) (Q38831)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Auxin response factor 5
- Auxin response factor 7
- Protein TRANSPORT INHIBITOR RESPONSE 1
- Auxin response factor 18
- Auxin transporter protein 1
- Auxin response factor 9
- Auxin response factor 1
- Membrane magnesium transporter
- Auxin response factor 6
- Auxin response factor 3
Sequence:
MITELEMGKGESELELGLGLSLGGGTAAKIGKSGGGGAWGERGRLLTAKDFPSVGSKRAADSASHAGSSPPRSSSQVVGWPPIGSHRMNSLVNNQATKSAREEEEAGKKKVKDDEPKDVTKKVNGKVQVGFIKVNMDGVAIGRKVDLNAHSSYENLAQTLEDMFFRTNPGTVGLTSQFTKPLRLLDGSSEFVLTYEDKEGDWMLVGDVPWRMFINSVKRLRVMKTSEANGLAARNQEPNERQRKQPV
Protein: Histone H2A.1 (P04911)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H2B.1
- Histone H2A.2
- Histone H3
- Histone H2B.2
- Histone H4
- FACT complex subunit SPT16
- FACT complex subunit POB3
- Histone H3-like centromeric protein CSE4
- Nucleosome assembly protein
- Histone H2A.Z
Sequence:
MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKATKASQEL
Protein: Late embryogenesis abundant protein 3 (LEA 3) (Q9SA57)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: LEA proteins are late embryonic proteins abundant in higher plant seed embryos. The function of those proteins is not known.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25005920}. Nucleus {ECO:0000269|PubMed:25005920}.
Interaction partners:
- F6D8.10
- Oil body-associated protein 2A
- Probable protein phosphatase 2C 28
- At2g23110
- Protein SENESCENCE-ASSOCIATED GENE 21, mitochondrial
- Gb|AAF18257.1 hydroxyproline-rich glycoprotein family)
- Agamous-like MADS-box protein AGL81
- Late embryogenesis abundant domain-containing protein / LEA domain-containing protein
- Late embryogenesis abundant
- Desiccation-related protein At2g46140
Sequence:
MAQHQHSPQRPRDQDNTRPHDQYGIVFSVSGDDVARKQGDSFSQPDPTVATMGSVDTVTIGEALEATALSLGDKPVDRRDAAAIQAAETRATGESKGRPGGLAVAAQAAATTNEQTVSEEDKVNIADILTDAAERLPGDKVVTSEDAEAVVGAELRSSSEMKTTPGGVADSMSAGARLNQQL
Protein: Solute carrier family 7 member 11 (A0A8I6AB70)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MVRKPVVATISKGGYLQGNVSGRLPSVGDQEPPGHEKVVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTGSVGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILEPFFIQCEIPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQLIKGQTHHFKDAFSGRDTNLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGYVLTNVAYFTTISAEELLQSSAVAVTFSERLLGKFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVHKHTPLPAVIVLHPLTMIMLFSGDLYSLLNFLSFARWLFMGLAVAGLIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVVLSLYSDPFSTGVGFLITLTGVPAYYLFIVWDKKPKWFRRLSDRITRTLQIILEVVPEDSKEL
Protein: Photosystem I reaction center subunit III (PSI-F) (P29256)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Probably participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.
Interaction partners:
- Photosystem I reaction center subunit IV
- Photosystem I reaction center subunit IX
- Photosystem I P700 chlorophyll a apoprotein A1
- Photosystem I iron-sulfur center
- Iron stress-induced chlorophyll-binding protein
- Photosystem I reaction center subunit XI
- Photosystem I reaction center subunit PsaK 1
- Photosystem I reaction center subunit PsaK 2
- Photosystem I reaction center subunit VIII
- Photosystem I P700 chlorophyll a apoprotein A2
Sequence:
MKHLLALLLAFTLWFNFAPSASADDFANLTPCSENPAYLAKSKNFLNTTNDPNSGKIRAERYASALCGPEGYPHLIVDGRFTHAGDFLIPSILFLYIAGWIGWVGRSYLIEIRESKNPEMQEVVINVPLAIKKMLGGFLWPLAAVGEYTSGKLVMKDSEIPTSPR
Protein: 1700074P13Rik protein (Serine protease 59) (Q9D9G7)
Organism: Mus musculus (Mouse)
Interaction partners:
- RIKEN cDNA 4933409G03 gene
- RIKEN cDNA 4932414N04 gene
- Lebercilin-like protein
- Protein FAM178B
- T-complex-associated testis expressed 2
- Gene model 57858
Sequence:
MKTFFIFTLLSLAVANTPKAVLKEYNNSEEYLPENFNVPYMVYLQSSPEPCVGTLIDPQWVLTAAHCSLPTKIRLGVYRPNIKNEKEQICNYSFTVVHPNFDAKLLKNDLMLIKLSYPATINMYVGTIAIAMEPMAFNESCFIPTWTWNNYKNLSDPDILTWINEYSLSPSDCLDTLHQQKQETRINIMCIGHSLNAMSATKEVSAAPAICSGRVHGILSWGKASVANGSKGFFTEIHPYARWILKMIRSH
Protein: Glutathione S-transferase (Q9NA96)
Organism: Caenorhabditis elegans
Interaction partners:
- Glutathione S-transferase omega
- Glutaredoxin-related protein 5, mitochondrial
- Glutathione transferase omega-1
Sequence:
MPTYKLTYFNSRWFAEPARILFQLAGVPFEDFRFTRGNGTWEKLKDKTPFGQVPVLTVDGFDIPQSSAIIRYLANKFGYAGKTPEEQAWADAICDQVKDFIDSFKQIVIAKRDGKTAEEIEKIHTEIFLPAKDSYFKIINGILEKSKSGFLVGDSLTFADIVVVENFTTLDKNHYCNASEQPRLTALREKVYAIPAIKHWVETRPDTVL
Protein: Pumilio homolog 24 (APUM-24) (AtPUM24) (Q9LRZ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:20214804}.
Interaction partners:
- Ribosome production factor 2 homolog
- Probable rRNA-processing protein EBP2 homolog
- Pumilio homolog 23
- Expressed protein family protein)
- Ribosome biogenesis regulatory protein homolog
- Ribosome biogenesis protein BRX1 homolog 2
- AT5g04600/T32M21_200
- Ribosome biogenesis protein BRX1 homolog 1
- Peter Pan-like protein
- DEAD-box ATP-dependent RNA helicase 13
Sequence:
MSSKGLKPQKSTKRKDTDSSAKFDSLKSKKPKLVSGEQQQHVKPKFGKPKSAGDKEQSTNLSKKERRVQAKELTEARKKKRKPHYNLEQELVSLWEKMRRRNIGKEDRSKLISEAIRKMKGKVPEIAVSHVSSRVLQTCVKFCSQAEKDVLFTELQPQFLNLASNKYAVHFIQKMLDGASKQQLAACISSLRGHVAPLLRHVFGSLVVEHAYHLGSAAQKQELLAELYSTELQLFKGLTTSNEKTVVDIIAKLGLQKGAVNRHMTAIIQPILEKGIVDHTITHKLLIEYLTIADKTSAADVLQLLTGSLLLRMVHTRDGSRLAMLSIKHGSAKERKKIIKAMKEHVKKMAFDQFGSMVLACIFSIVDDTKLVTKIIVRELEATLKDLVMDKNGRRPLLQLLHPNSSRYLSHDDLAALDLSVPSLCSMDKSETSSKTKDTDGNEIGEETKDEQEDTVAEHSDHEENVTAMGGKKDPLVRRQELLVNSGLAERLIDVCVENAEEFLQSKFGNEVMYEVAIGGSDGILCPSLSEKLCELYEAISSVAAEPKPQESEKDSEHILENFHSSRTIRRLVLNRPGFASILFKKALSGKCRSWAQGHCSKILSAFVETEDVQVREMAKTELQVLVNEGTLKISATKKPE
Protein: Uncharacterized protein, isoform A (Uncharacterized protein, isoform B) (M9PBA3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKFLSILVALCLLLALTISPISCDDTEKVVRPICPCPRNYEPVCGSNLVTYPNRCEFDCVRRNVERQGRSMGLLRDGTC