wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein DDB_G0288133 (Q54JD4)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Small ribosomal subunit protein eS30
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL3
Sequence:
MDKSKNLFDLLQDDEEVEKKPTTKSTQAAAAPVAAKKPVAPKTENKVENRSPKLGGQSKPKRVNNGEQQVATSEERQNTKRDSKSYPKHQPRTDATGNIRNRQFDRKSGTGRPHNENKKGGAGQGNWGKEGSVDAETNVATVTPTEGEKESTEPVVAAPVEDKTLTLGEYLKQQGSVTLEAPKLRVAGEGETKNAQWDEFEPIQREVVKQRDTKSVKEEKKTKKNVIQVELKSAPSTQRPKGNTKKVVKGVDVTDVNIFPSLSKA
Protein: NADH-ubiquinone oxidoreductase chain 1 (EC 7.1.1.2) (NADH dehydrogenase subunit 1) (P03889)
Organism: Rattus norvegicus (Rat)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03887}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Cytochrome c oxidase subunit 3
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 1.
- NADH dehydrogenase 1 alpha subcomplex subunit 6
- Cytochrome c oxidase subunit 2
- NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
Sequence:
MYFINILTLLIPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWIPLPMPHPLINLNLGMLFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMSGSFSLQMLITTQEHIWLLIPAWPMAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTSIVFLGPLYHINYPELYSTSFMTETLLLSTTFLWIRASYPRFRYDQLMHLLWKNFLPLTLAFCMWYISLPIFLAGIPPYT
Protein: Pseudo histidine-containing phosphotransfer protein 6 (Histidine-containing phosphotransfer protein 6) (Q9SSC9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8L9T7}. Nucleus {ECO:0000250|UniProtKB:Q8L9T7}.
Interaction partners:
- Histidine kinase 4
- Histidine kinase 3
- Histidine kinase 2
- Two-component response regulator ARR1
- Two-component response regulator ARR12
- Two-component response regulator ARR10
- Two-component response regulator ARR18
- Two-component response regulator ARR2
- Two-component response regulator ARR14
- Two-component response regulator ARR11
Sequence:
MLGLGVDRLQADINRLLASLFHQGVLDEQFLQLQQLQDETSPNFVYDVINIYFDESEKLLRNLRLLLMDREFSDYKKIGLHLNQLVGSSSSIGARRVRNVCVAFRSASELSNRPGCLRGLEVVEHEYHYLKNMMHELFQLEQQRILAAGVRYPM
Protein: Glycoside hydrolase family 57 N-terminal domain-containing protein (Q728Y0)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- histidine kinase
Sequence:
MARHLCIHGHFYQPPREDPWQGDVLPEGSAAPAHDWNERIHRESYAPLAWARRLDANGRIADIMNCYEWMSFNVGPTLLRWMDRHAPDTLRRMVEGDRQSLARWGHGNALAQVYHHIIMPLATVRDREMEVAWAVDDFMHRFGRKPEGMWLAESAADLPSLETLADAGIAFTILAPRQARAVAMLDGRPADDAAWMPVDEHSLDIREPYLVELPSGRSMAVFFYDGALSRAVAFERLLQDGEGFWRRLVGAAGPGLLSVCTDGETYGHHFTFGEMALAHVLGQGYSGRDDLRLTNYAAQLERTPPRRRVLLHEPSSWSCAHGVERWRSDCGCTDGGHPGWNQRWRKPLREGLDAMKREIDAHFSRRGASLFYDPWAALRGYGKVLATQSTAAATPSADSAQPAAPGTALPDALEDARSTFAAKHLRPDLAPSDIDTAWRLLAMQEAALAAFASCAWFFDEISRIEPVNAMTYALRASDLAAATGTGDIHRHLLEHLQRAVSNKPEEGTGADIFTHHALPRRETVPGLVLQALCLLEAADALPAAGDTATWTWPGAQVAVRLESAPGDVPLQGMAEVRLALEPGGETVHFAWTPPHATGATGSLVRVVRADGTQEAMRLMDLARNRREALLAALTTGATRRADELLGPVARMMLPLVSPWEEAQRDMVRSEAWAPLLPTLGLATITGCGASPETLRLVEDYLRANLGAGDRRRLARLAEGMFTELLDAPEPDWDKIERRIVRTRALLPDMDWWSVQNRIWQWGLAGEGPRRCAVQLGFRV
Protein: Probable phospholipase C20G8.02, mitochondrial (P87109)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable phospholipase that hydrolyzes phosphatidic acid.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MILYIVLPFYVRTKPYSILPSYSSLQWITNAWCSLPSIYILCHCSKHQEEITILALKPLIAMNNSEEWPLKHVQPPKLSFRHLLSRSVTDAPSLRVRWFYAVDRPLRKSRTGPTEIKKAKNFLPFSAEDSEHIEKSYLKAVENDGQSEPVNVNEDYLYSVNVVSRELSPIYWDGPVYRILRGTWFFSRGDKLYPCEENLATQVEEGYLNSCPYREFSNEKDSAAAQSKTWALLGRYTGGFVQYTGSRNARLVYDDFYRNVSVKIMNRFSPASFHRSDKLVRGYELDMLESNSKPSTPVPTEELTSTTLLNDSSDPSDNFTPSNTESTIDLPSATDASHLMSRPDREVNHLILCCHGIGQKMGERVETVSFVKDISNFRKTLKKTFNSSPDLQAVYPKLKGGGNGVQCLPLLWRQDIRFGMARDLDSSFADDDDDDDESLNMSRDLALDDLEDDSIPTLDNINIPTVTGLRNIISDVLLDVLLYCQPNYRDKILAAVVKRLNRLYNLYKKNVPSFNGHVSLLGHSLGALILFDIIRYQGNIKYSKLQLDFPVANFFALGSPLGLFQMLNGKKIAGPIPKTNLTRSLSYSEQSFDSGVSILSCQNFYNIFHPTDPISYRVEPLVVKQMARLKPQKISHFRPHQDLSSSGVGHKIAGGALNVLSGLRSGIANTLILKSLSYASVFNEATADSHDESQGAENIRDWHIDERMYRLNKTGRIDFMLQEGALDTSYSYVSAMNAHSEYWKNVDLAHFILTQLL
Protein: BSD domain-containing protein 1 (Q9NW68)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLATEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE
Protein: Olfactory receptor 2J3 (Hs6M1-3) (Olfactory receptor OR6-16) (OR6-6) (Olfactory receptor 6-6) (O76001)
Organism: Homo sapiens (Human)
Function: Odorant receptor involved in the detection of the flavor compound cis-3-hexen-1-ol (C3HEX), a compound typically described as 'green grassy' or the smell of 'cut grass'.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MNDDGKVNASSEGYFILVGFSNWPHLEVVIFVVVLIFYLMTLIGNLFIIILSYLDSHLHTPMYFFLSNLSFLDLCYTTSSIPQLLVNLWGPEKTISYAGCMIQLYFVLALGTTECVLLVVMSYDRYAAVCRPLHYTVLMHPRFCHLLAVASWVSGFTNSALHSSFTFWVPLCGHRQVDHFFCEVPALLRLSCVDTHVNELTLMITSSIFVLIPLILILTSYGAIVRAVLRMQSTTGLQKVFGTCGAHLMAVSLFFIPAMCIYLQPPSGNSQDQGKFIALFYTVVTPSLNPLIYTLRNKVVRGAVKRLMGWE
Protein: Rho GTPase-activating protein 68F (Q9VTU3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Functions as a GTPase-activating protein (GAP) for RhoA/Rho1 during gastrulation by converting it to an inactive GDP-bound state.
Interaction partners:
- Ras-like GTP-binding protein Rho1
- Ras-related protein Rac1
- FI17866p1
- Cdc42 homolog
- Uncharacterized protein, isoform A
- Ras-like GTP-binding protein RhoL
Sequence:
MDAHSRFAPRLPGPAINPIVDNSDEPQPSLSDLHDFEPKLEFDDTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPLEDDFEDQLREQSENFQTPRNKCDFLGTDKQGRHIFGIYASRFPEKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIYLIDVNQRTVSVD
Protein: Phosphatidate cytidylyltransferase (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (CDS) (CDP-diglyceride pyrophosphorylase) (CDP-diglyceride synthase) (CDP-DG synthase) (CTP:phosphatidate cytidylyltransferase) (P38221)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Supplies CDP-diacylglycerol, which may play an important role as both a precursor to phosphoinositide biosynthesis in the plasma membrane and as a negative effector of phosphatidylinositol 4-kinase activity, thereby exerting an effect on cell proliferation via a lipid-dependent signal transduction cascade.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle. Note=Exclusively present in the ER, and not in mitochondria. Also associated with post-Golgi apparatus secretory vesicles destined for the plasma membrane.
Interaction partners:
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
- Cardiolipin synthase
- Phosphatidic acid phosphohydrolase 1
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- Phospholipase D1
- Lysophospholipid acyltransferase
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- CTP-dependent diacylglycerol kinase 1
- Diacylglycerol pyrophosphate phosphatase 1
Sequence:
MSDNPEMKPHGTSKEIVESVTDATSKAIDKLQEELHKDASESVTPVTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS
Protein: Lysine-specific demethylase 5B (EC 1.14.11.67) (Cancer/testis antigen 31) (CT31) (Histone demethylase JARID1B) (Jumonji/ARID domain-containing protein 1B) (PLU-1) (Retinoblastoma-binding protein 2 homolog 1) (RBP2-H1) ([histone H3]-trimethyl-L-lysine(4) demethylase 5B) (Q9UGL1)
Organism: Homo sapiens (Human)
Function: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000269|PubMed:10336460, ECO:0000269|PubMed:12237901}.
Interaction partners:
- Lysine-specific histone demethylase 1A FAD-dependent demethylase 1A)
- Histone deacetylase 1
- Myc proto-oncogene protein
- Transcription factor AP-2 gamma
- REST corepressor 1
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- Forkhead box protein G1
Sequence:
MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK
Protein: PNN interacting serine and arginine rich protein (A0A2R8Y2Y1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVEQPPGMMPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR
Protein: Uncharacterized protein, isoform A (Uncharacterized protein, isoform B) (A1Z971)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}.
Interaction partners:
Sequence:
MPCESCGVEFTVFRRKRACFDCKRYYCANCIASRRCKRCSVFAQRPLSRTDLLKLKPKDLIFYLQSKHISTEGCLEKEELVGLVLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQATTTNGGSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSERVSISLKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQSSFEELGAIGGISDESKANTDTNSSHLDQWQVLEVNRIEAVEETPTTSAADEILEVTLRSRPAVEGDDSEMGESTQALNVNQRPANPSPAFYPAVPQRTKKVTRRRSDGYLNRRYHSSDDESPVAPGGPGLSLGLSTLSEHPEHGLHPHSHRQSCQRCGKNKTNIRRHVEKMRRHLENSQMSEEDIKRELQEFLTYLEQRTKSVDASDADSHAVSPLSVDAISVAAGGRSPDMPITPTIEFSPTQDEDIRWDDDEGIHVYAAPSDFEPTAGIDSRFVNLEDFEDLKDLEGLTVKQLKEVLMLHRVDYKGCCEKQELLDRVSRLWKTMRECPAVEKLATDELCKICMDAPIECVFLECGHMATCTSCGKVLNECPICRQYIVRVVRFFRA
Protein: bZIP transcription factor ABI5 homolog (OsABI5) (bZIP transcription factor 10) (OsBZIP10) (Q8RZ35)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor that possesses transactivation activity in yeast. Involved in abscisic acid (ABA) signaling pathway. Binds to the G-box motif 5'-CACGTG-3' of TRAB1 gene promoter. Involved in the regulation of pollen maturation. May act as negative regulator of salt stress response. Together with PYL5, PP2C30 and SAPK2, is part of an ABA signaling unit that modulates seed germination and early seedling growth.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:18236009, ECO:0000269|PubMed:21055780, ECO:0000269|PubMed:22071266, ECO:0000269|PubMed:28000033}.
Interaction partners:
- Serine/threonine-protein kinase SAPK2
- Serine/threonine-protein kinase SAPK10
- Serine/threonine-protein kinase SAPK8
- B3 domain-containing protein VP1
- Serine/threonine-protein kinase SAPK9
- Serine/threonine-protein kinase SAPK3
- Serine/threonine-protein kinase SAPK6
- Serine/threonine-protein kinase SAPK1
- Serine/threonine-protein kinase SAPK7
- Serine/threonine-protein kinase SAPK4
Sequence:
MASEMSKNVKVTDDQEVTSQERDQSGGTKVGGEEEIAPLARQSSILSLTLEELQNSLCEPGRNFGSMNMDEFVANIWNAEEFQATTGGCKGAMEEAKVVDSGSGSGDAGGSGLCRQGSFSLPLPLCQKTVEEVWTEINQAPAHTSAPASALQPHAGSGGVAANDRQVTLGEMTLEDFLVKAGVVRGSFTGQAAMGSGMVNGPVNPMQQGQGGPMMFPVGPVNAMYPVMGDGMGYPGGYNGMAIVPPPPPAQGAMVVVSPGSSDGMSAMTHADMMNCIGNGMMIENGTRKRPHREDGCAEKTVERRQRRMIKNRESAARSRARKQAYTVELEAELNYLKQENARLKEAEKTVLLTKKQMLVEKMMEQSKEKMNANRGGSQLRRSGSCMW
Protein: Ubiquitin carboxyl-terminal hydrolase 9 (EC 3.4.19.12) (Deubiquitinating enzyme 9) (Ubiquitin thioesterase 9) (Ubiquitin-specific-processing protease 9) (P39967)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- DUB-associated factor 1
- OTU domain-containing protein 2
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin thioesterase OTU1
- Ubiquitin carboxyl-terminal hydrolase 2
Sequence:
MIKRWLSVNRKKSHPEKNTQGNDEINRKATSLKKTKGSGDPSIAKSPSAKSSTSSIPSNLASHERRSKFSSQTDNLAGNKHYHEHYHNMASTSDEREYDSSTTYEDRAFDTESSILFTTITDLMPYGDGSNKVFGYENFGNTCYCNSVLQCLYNIPEFRCNVLRYPERVAAVNRIRKSDLKGSKIRVFTNESFETSTNSGNSNTGYQSNDNEDAHNHHHLQQSDQDNSSSSTQEKQNNFERKRNSFMGFGKDKSNYKDSAKKDDNNEMERPQPVHTVVMASDTLTEKLHEGCKKIIVGRPLLKQSDSLSKASTTDCQANSHCQCDSQGSRITSVDDDVLVNPESCNDAVNNSNNNKENTFPTSEQRKKAALIRGPVLNVDHLLYPTEEATLYNGLKDIFESITENLSLTGIVSPTEFVKILKKENVLFNTMMQQDAHEFLNFLLNDFSEYIQRNNPRMRFGPQKTDNSNDNFITDLFKGTLTNRIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLDVSSTFNTSVYKKYELSGVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFYKETQADKTENQNENIDTSSQDQMQTDNNIEQLIKCDDWLRDRKLRAAANIERKKTLGNIPEVKTAETKTPLNDKKRNKQKRKSRILSFIK
Protein: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1) (P07153)
Organism: Rattus norvegicus (Rat)
Function: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:E2RQ08}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:E2RQ08}.
Interaction partners:
- Serine/threonine-protein kinase Chk1.
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
- Tumor suppressor candidate 3
- Malectin
- Oligosaccharyltransferase complex subunit OSTC
- Protein transport protein Sec61 subunit alpha isoform 1
Sequence:
MEAPIVLLLLLWLALAPTPGSASSEAPPLVNEDVKRTVDLSSHLAKVTAEVVLAHPGGGSTARASSFVLALEPELESRLAHLGVQVKGEDEEDNNLEVRETKMKGKSGRFFTVKLPVALDPGSKISIVVETVYTHVLHPYPTQITQSEKQFVVFEGNHYFYSPYPTKTQTMRVRLASRNVESHTKLGNPSRSEDILDYGPFKDIPAYSQDTFKVHYENNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGISSIRSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRFGLFGGWKTHYIVGYNLPSYEYLYNLGDQYALKMRFVDHVFDEQVIDSLTVKIILPEGAKNIQVDSPYDISRAPDELHYTYLDTFGRPVIVAYKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFFTVIIYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRLGLYRHFDETVNRYKQSRDISTLNSGKKSLETEHKAVTSEIAVLQSRLKTEGSDLCDRVSEMQKLDAQVKELVLKSAVEAERLVAGKLKKDTYIENEKLSSGKRQELVTKIDHILDAL
Protein: 1-aminocyclopropane-1-carboxylate oxidase 2 (ACC oxidase 2) (AtACO2) (EC 1.14.17.4) (Q41931)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Enzyme involved in the ethylene biosynthesis. Required to mediate the 1-aminocyclopropane-1-carboxylic acid (ACC)-mediated reversion of the ABA-induced inhibition of seed germination via endosperm rupture. May promote stem elongation by maximizing the extensibility cells, possibly by activating ethylene biosynthesis, in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0).
Interaction partners:
- 1-aminocyclopropane-1-carboxylate synthase-like protein 1
- 1-aminocyclopropane-1-carboxylate synthase 2
- 1-aminocyclopropane-1-carboxylate synthase 7
- 1-aminocyclopropane-1-carboxylate synthase 5
- 1-aminocyclopropane-1-carboxylate synthase 4
- 1-aminocyclopropane-1-carboxylate synthase 6
- 1-aminocyclopropane-1-carboxylate synthase 11
- 1-aminocyclopropane-1-carboxylate synthase 9
- 1-aminocyclopropane-1-carboxylate synthase 8
- Aconitate hydratase 1
Sequence:
MEKNMKFPVVDLSKLNGEERDQTMALINEACENWGFFEIVNHGLPHDLMDKIEKMTKDHYKTCQEQKFNDMLKSKGLDNLETEVEDVDWESTFYVRHLPQSNLNDISDVSDEYRTAMKDFGKRLENLAEDLLDLLCENLGLEKGYLKKVFHGTKGPTFGTKVSNYPPCPKPEMIKGLRAHTDAGGIILLFQDDKVSGLQLLKDGDWIDVPPLNHSIVINLGDQLEVITNGKYKSVLHRVVTQQEGNRMSVASFYNPGSDAEISPATSLVEKDSEYPSFVFDDYMKLYAGVKFQPKEPRFAAMKNASAVTELNPTAAVETF
Protein: Protein enhancer of rudimentary (Q24337)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as an enhancer of the rudimentary gene. Has a role in pyrimidine biosynthesis and the cell cycle.
Interaction partners:
- Probable small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein F
- Probable small nuclear ribonucleoprotein G
- Probable small nuclear ribonucleoprotein Sm D2
- Probable small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D3
- RE74585p
- LP09875p
Sequence:
MSHTILLVQPGARPETRTYCDYESVNECMEGVCKIYEEHLKRRNPNTPTITYDISQLFDFIDTMVDISCMVYQKSTNTYAPYNKDWIKEKIYVLLRQAAFSSNT
Protein: Peptidase M1 family protein (F4I3R1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MARLIIPCRSSSLARVNLLGLLSRAPVPVRSSCLRSSANRLTQHRPFLTSEAICLRKNRFLPHSVDTHKQNSRRLICSVATESVPDKAEDSKMDAPKEIFLKNYTKPDYYFETVDLSFSLGEEKTIVSSKIKVSPRVKGSSAALVLDGHDLKLLSVKVEGKLLKEGDYQLDSRHLTLPSLPAEESFVLEIDTEIYPHKNTSLEGLYKSSGNFCTQCEAEGFRKITFYQDRPDIMAKYTCRVEGDKTLYPVLLSNGNLISQGDIEGGRHYALWEDPFKKPCYLFALVAGQLVSRDDTFTTRSGRQVSLKIWTPAEDLPKTAHAMYSLKAAMKWDEDVFGLEYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLASPETATDADYAAILGVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDMGSRTVKRIADVSKLRIYQFPQDAGPMAHPVRPHSYIKMDNFYTVTVYEKGAEVVRMYKTLLGTQGFRKGIDLYFERHDEQAVTCEDFFAAMRDANNADFANFLQWYSQAGTPVVKVVSSYNADARTFSLKFSQEIPPTPGQPTKEPTFIPVVVGLLDSSGKDITLSSVHHDGTVQTISGSSTILRVTKKEEEFVFSDIPERPVPSLFRGFSAPVRVETDLSNDDLFFLLAHDSDEFNRWEAGQVLARKLMLNLVSDFQQNKPLALNPKFVQGLGSVLSDSSLDKEFIAKAITLPGEGEIMDMMAVADPDAVHAVRKFVRKQLASELKEELLKIVENNRSTEAYVFDHSNMARRALKNTALAYLASLEDPAYMELALNEYKMATNLTDQFAALAALSQNPGKTRDDILADFYNKWQDDYLVVNKWFLLQSTSDIPGNVENVKKLLDHPAFDLRNPNKVYSLIGGFCGSPVNFHAKDGSGYKFLGDIVVQLDKLNPQVASRMVSAFSRWKRYDETRQGLAKAQLEMIMSANGLSENVFEIASKSLAA
Protein: Zinc finger and BTB domain-containing protein 24 (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1) (Zinc finger protein 450) (Q80X44)
Organism: Mus musculus (Mouse)
Function: May be involved in BMP2-induced transcription.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Nucleoredoxin-like protein 1
- Zinc finger protein 18
- Solute carrier family 2, facilitated glucose transporter member 1
Sequence:
MADTTPEPCGQLMVHSDTHSDTVLASLEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKTTEQILATAQFLKVYDLVKAYADFQDNHSAPKPPALNCTGTPVVVISNKKNDPLKRKRGRPRKANGLQEGRSELAAEGELQLRVNNSVQNRQNFVFKEEDSVKLSEQTPEDKESEPAGEPGSVEEVPAEKDENFDPKAGDGQESQSRCSRRRIRRSVKLKDYKLLGDEDDQSTAKRLCGRKKRSSGPEARCKDCDRVFKYSHFLAIHQRRHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCGKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECSHCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSDSSAKRRHCILHTGKKPFSCPECGLQFARLDNLKAHLKIHSKEKHTADSSSVSGSNVDEGRNILQLQPYQLSTSGEQEIQLLVTDSVHNINFMPGPSQGVSIVAAESPQSMATDPAANITLLTQQPEQLQGLILSAQQEQAEHIQSLSVIGGQMESSQTEPVHVITLSKETLEHLHAHQEQTTSSVPAADTGARATPVPSTRPGAELTQAPLAVPLDPSPGATVAGWPFGPSSYRSLKM
Protein: Elongator acetyltransferase complex subunit 5 (I3L200)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XLVYHDFFRDPLNWSKTEEAFPGGPLGALRAMCKRTDPVPVTIALDSLSWLLLRLPCTTLCQVLHAVSHQDSCPDSVVLHPSGLQPGSPRGALCRVPALLRSSYTPGI