wanglab/gogpt-training-data huggingface dataset:
Protein: BLOC-2 complex member HPS3 (Cocoa protein) (Hermansky-Pudlak syndrome 3 protein homolog) (Q91VB4)
Organism: Mus musculus (Mouse)
Function: Involved in early stages of melanosome biogenesis and maturation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11707070}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q969F9}.
Interaction partners:
- BLOC-2 complex member HPS5
- BLOC-2 complex member HPS6
- Biogenesis of lysosome-related organelles complex 1 subunit 3
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- BLOC-3 complex member HPS1
- Biogenesis of lysosome-related organelles complex 1 subunit 5
- BLOC-3 complex member HPS4
- Dysbindin
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- SNARE-associated protein Snapin
Sequence:
MVRLYNLHPFGSQQVVPCQWEPEQVCCGGSDALFVAAGCKVEAFAVQGEELCRQRCAFSTLGRVLRMAYSEAGDYLVAIEEKNKTIFLRAYVNWRSKRSDNSRVCIRMVGHNVEASFCESFRDQMSIIEMPMSEAPLCFSCCPVKGDLLVGCTNKLVLFTLKYDIINEEFSILNFERSLIIHIDNITPVEISFCVGYVAVMSDLEVLLLKLESDPIHGESVDHHPQETSNPLKEAEGVSNETSQLESEDFVICLKPMELIGEKCEQSGISVKLESTGLEDEKVKYLRVRHLLYRRFAPDISSYVLSDNIKLHSLQLLPIHQSGFHPDENDLSPKKEMPNLFCFFSLPHVGYLYMVVKSVELMSVYWYPEKSQQAVLTPQFLHVITSQSLQCFTVRCSAAVAHEEDLYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRESPKKLISRKDASVRSGTPHVAEAAWNLYLVNTTAPVQLYKEMVDYSNSYKTVKTESCLHLLSEAHLLVRAALMDGSQLEPAEKAELLEAFKESCGHLGDCYSRLTTEQSHLALPYYKMSGLSLAEVLARVDWTEESESQKYERGLVFYINHSLYENLDEELSKELAAKVAQIFHMAEPKQLPHVLSSPSMKNIDPLTALHYLRKLDSCGVSPVLVTLTKAAVALKMGDLDMYRNEMKSHSEMKLVYGFILEPRLLIQQWKGQIVPTELAIDLKETQPGLLVASVLGLQKNDKIGIVETDSFFKVLCGKDEDAVPQLLIDFWEAQLVACLPNVVLEELFFKLISQYVWRLSERRCPDTVPLRTAEDLINACSHYGLVNPWVHVLTTSDSLADKNYTDDLLKLQSLICSPSLDVASIIPFLEPLSEDTVAGLSTHALCHTRLQEYEQCIDTLLERCPEAVIAYANQELKEDHWILWWKKLLPELCQRVKSGGERSHLHLSLLKETLSVIAVGLDLRDFLNVLPEDGAAAFFLPYLLFCSRKKSLT
Protein: Putative fucosyltransferase-like protein (FucT2) (FucTB) (Fucosyltransferase 12) (AtFUT12) (Q9FX97)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in cell wall biosynthesis. May act as a fucosyltransferase.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}.
Interaction partners:
- Beta-1,2-xylosyltransferase
- Beta-1,3-galactosyltransferase GALT1
- Beta-hexosaminidase 1
- Beta-hexosaminidase 3
- Beta-hexosaminidase 2
- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Alpha-mannosidase 2
- Glycoprotein 3-alpha-L-fucosyltransferase A
- Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Dol-P-Man:Man
Sequence:
MGVFSNLRGPRAGATHDEFPATNGSPSSSSSPSSSIKRKLSNLLPLCVALVVIAEIGFLGRLDKVALVDTLTDFFTQSPSLSQSPPARSDRKKIGLFTDRSCEEWLMREDSVTYSRDFTKDPIFISGGEKDFQWCSVDCTFGDSSGKTPDAAFGLGQKPGTLSIIRSMESAQYYPENDLAQARRRGYDIVMTTSLSSDVPVGYFSWAEYDIMSPVQPKTERAIAAAFISNCGARNFRLQALEALMKTNIKIDSYGGCHRNRDGKVDKVEALKRYKFSLAFENTNEEDYVTEKFFQSLVAGSVPVVVGPPNIEEFAPASDSFLHIKTMEDVEPVAKRMKYLAANPAAYNQTLRWKYEGPSDSFKALVDMAAVHSSCRLCIFLATRVREQEEESPNFKKRPCKCSRGGSDTVYHVFVRERGRFEMESVFLRGKSVTQEALESAVLAKFKSLKHEAVWKKERPGNLKGDKELKIHRIYPLGLTQRQALYNFKFEGNSSLSSHIQNNPCAKFEVVFV
Protein: N-alpha-acetyltransferase 10 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (hARD1) (NatA catalytic subunit Naa10) (P41227)
Organism: Homo sapiens (Human)
Function: Catalytic subunit of N-terminal acetyltransferase complexes which display alpha (N-terminal) acetyltransferase activity. Acetylates amino termini that are devoid of initiator methionine. The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development. Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX. Acetylates HIST1H4A. Acts as a negative regulator of sister chromatid cohesion during mitosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12464182, ECO:0000269|PubMed:25489052, ECO:0000269|PubMed:25732826}. Nucleus {ECO:0000269|PubMed:12464182, ECO:0000269|PubMed:15496142, ECO:0000269|PubMed:25732826}. Note=Also present in the free cytosolic and cytoskeleton-bound polysomes. {ECO:0000269|PubMed:15496142}.
Interaction partners:
- N-alpha-acetyltransferase 50
- N-alpha-acetyltransferase 16, NatA auxiliary subunit
- N-alpha-acetyltransferase 15, NatA auxiliary subunit
- Huntingtin-interacting protein K
- N-alpha-acetyltransferase 35, NatC auxiliary subunit
- N-alpha-acetyltransferase 30
- N-alpha-acetyltransferase 60
- N-alpha-acetyltransferase 38, NatC auxiliary subunit
- N-alpha-acetyltransferase 11
- N-alpha-acetyltransferase 25, NatB auxiliary subunit
Sequence:
MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
Protein: EF-hand domain-containing protein (A0A060WH27)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Myosin, light chain 13
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- Myosin, light chain 13
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- EF-hand domain-containing protein
Sequence:
MFEQAQIQEFKEAFTIMDQNRDGFIDKNDLRDTFCALGRLNVGNDELDEMLKMAPGPINFTIFLSMFGEKLKGTDPEETIINAFKIFDPEGQGVLKGEDIKYYIMSQADKFTEAEVEDMFTNFPLDVAGNLDYKNLCYVITHGEDKEAE
Protein: EGF containing fibulin-like extracellular matrix protein 1 isoform 2 (HCG16977, isoform CRA_b) (A0A0S2Z3V1)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
Protein: Probable maltase-glucoamylase 2 (Maltase-glucoamylase (alpha-glucosidase) pseudogene) [Includes: Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha-glucosidase)] (Q2M2H8)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Alpha-amylase 2B
- demerged
- Pancreatic alpha-amylase
- Maltase-glucoamylase
- Glycogen phosphorylase, liver form
- Glycogen phosphorylase, brain form
- Glycogen phosphorylase, muscle form
- 1,4-alpha-glucan-branching enzyme
- Sucrase-isomaltase, intestinal
- Glycogen debranching enzyme
Sequence:
MARKLSVLEVLLIIFCLIVVTIDILLLLLVLEETSDTSFTPECPEIPQSERIDCTPDQEVTEDICRWQYKCCWSPVADANVPRCFFPWNWGYEASNGHTNTSTGFTAQLKRLPSPSLFGNDVATTLFTAEYQTSNRFHFKITDFNNIRYEVSHENINLVDGIADASNLSYYVEVTDKPFSIKIMRTSNRRVLLDTSIGPLQFAQQYLQLSFRLPSANVYGLGEHVHQQYRHNMTWKTWPIFTRDATPTEGMINLYGAHTFFLCLEDARGSSFGVFLMNSNAMEVTLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPFFPPYWSLGFQLSRRDYGGINKLKEVVSRNRLAEIPYDVQYSDIDYMDGKKDFTVDEVAYSGLPDFVKELHDNGQKYLIIMNPGISKNSNYEPYNNGSLKRVWILGSNGFAVGEGYPGPTVFPDYTNPVCTEWWTDQVAKFHDHLEFDGVWIEMNEVSSLLQASNNQCESNNLNFPPFLPRVLDHLLFARTLCMDTEFHGGLHYDIHSLYGHSMARTTNLALETIFMNNRSFILSRSTFAGSGKFAAHWLGDNAATWDDLRWSIPTILEFNLFGIPMVGANICGYNNNVTEELCRRWMQLGAFYPLPRNHNGPGFRDQDPAAFGVDSLLLKSSRHYLNIRYTLLPYLYTLFYHAHTRGETVARPLVHEFYQDSATWDVHEQFLWGPGLLITPVLYEGVDEVKAYIPDATWYDYETGVAISWRKQLVNMLLPGDKIGLHLRGGYIFPTQKPNTTTEASRRNSLGLIIALDYKREAKGELYWDDGVSKDAVTEKKYILYDFSVTSNHLQAKIINNNYMDTDNLMFTDITILGMDKQPANFIVLLNNVATSSPSVVYNASTKVVTITDLQGLVLGQEFSIRWNLPVSDLEKFNCYPDDPTASEESCRQRGCLWEDTSTPGVPTCYYDTIPNYVASDIQYLNTSITADLSLPMAPESAAAAASDSLSAKISFLHLKVIYHTATMLQVKIYDPTNKRYEVPVPLNTPPQPVGDPENRLYDVRIQNNPFGIQIQRKNSSTVIWDSQLPGFIFNDMFLSISTRLPSQYIYGFGETEHTTFRRNMNWNTWGMFAHDEPPAYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTLQPTPALTYRTTGGILDFYIVLGPTPELVTQQYTELIGRPAMIPYWALGFHLSRYGYQNDAEISSLYDAMVAAQIPYDVQHVDIDYMNRKLDFTLSANFQNLSLLIEQMKKNGMRFILILDPAISGNETQYLPFIRGQENNVFIKWPDTNDIVWGKVWPDLPNVIVDGSLDHETQVKLYRAYVAFPDFFRNSTAAWWKKEIEELYANPREPEKSLKFDGLWIDMNEPSNFVDGSVRGCSNEMLNNPPYMPYLESRDKGLSSKTLCMESQQILPDSSPVEHYNVHNLYGWSQTRPTYEAVQEVTGQRGVIITRSTFPSSGRWGGHRLGNNTAAWDQLGKSIIGMMEFSLFGIPYTGADICGFFGDAEYEMCVRWMQLGAFYPFSRNHNNIGTRRQDPVAWNSTFEMLSRKVLETRYTLLPYLYTLMHKAHVEGSTVVRPLLHEFTDDRTTWDIDRQFMLGPAILISPVLETSTFEISAYFPRARWYDYSTGTSSTSTGQRKILKAPLDHINLHVRGGYILPWQEPAMNTHSSRQNFMGLIVALDDNGTAEGQVFWDDGQSIDTYENGNYFLANFIAAQNILQIQTIHNKYLSDSNPLKVGYIRIWGVNTYVTQVSFTYDNRQFMETNFKSEPYNQILTIQLTDKTINLEKLTEVTWIDGGPVLPTPTKTSTIPMSSHPSPSTTNATSSETITSSASANTTTGTTDTVPITTTSFPSTTSVTTNTTVPDTTSPFPTSTTNASTNATVPITTTPFPTSTIGVTTNATVPNTTAPFPTNASTASTNATVPITTTCFATSTIGVTTNATVPDTTAPFPTNTTTASTNATIPITTTPFATSTISVTTSTTVPDTTAPFPTSTTSASTNATPVPITTTLFATSTIGVTTGTTVPDTTAPFPTSTTSTSTSATVPITTTPSPTNTADANTSNTVPNTTMPSPTSSTTVSTIATVPISVTPSLTSTADATISTTVLIATTSSLTGTTDVSTSTTINNISTPVQTNTTNASTSTNVANITATSHTSTDDTVPNNTVPVTAIPSLANTGVDTTSNSFSIMTTSFSESTNAMNTTVIMATTSPTSTDVASTNNDASMTNFLLATMSAGNITSNSISITTTSFGNSVPFVTTPSPSTDATTTSNNTNPGMTTYYQTSPTIPTHTLTSIPSSITSILSMFPTSNTFTTDKITNFTTPTNANTIIFNTLDTKSTMVIDATVTTTSTKDNTMSPDTTVTSIDKFTTHITQFATPHSATTTTLALSHTSLAPTNLSNLGTMDITDADNSSSVTGNTTHISVSNLTTASVTITATGLDSQTPHMVINSVATYLPITATSATTDTTNITKYALNTTTPDSTVHTSATAPTYIANAINATQVP
Protein: Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, isoform A (Q9W2J2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKEPTNTLDEIVPSRLTSAELRAMALRQQQQIDSQHQLLATKEQRLRFLKSQEVRSAVASAEGERLRRLRERVEAQESKLRRLRALRGQVDLQKTYNVTLSNDLDSIRALFSEKEKELSLAVAKVEALTRQLEELRRDRRCPVNILTAAGNGVGGQSLPPQASRELEKLRRELMYRNQLSLQQDARLHMQREALQQRQAELRSTDQRIYELQTRLQRKKQANTHHQQQQQQQQQHQQQQHQQQHQQTTVQQQQQQQQQLHVQSAQLLAAAAAATAQQQQQHQQHQQQQQQQQQQSASNLGKHGGVAALKQQLLQKQVNQLAAAAAAAAAGRARGNVAAVEPFIHTPQKSTITSTASYLSGGMKHAAATANTNQQNQLIQDLTHVKLGQNSGFFAGSVPVPVASSSCESDESKLAKKLLAAPAKTEAELRKQAQTEAMDSTTHIYAEVGPKKRDREAAAAAAAAAAAAAAAAQAAAEAANQAATAAAASAISPPATANASKIPKSTTSSSSSASALISKLNQQATAKESQDQQQSQAKKNEISVTSETLSERNTQQQLTVHSMPLGAISKSVALAVSNASKPLQVQVSNVAVPPRKPISSVAPNSVSSGSSIPKMITYSPKVNRVAPNVVMTDPRPALPPKPSKMSPTEQPSPVEANTSGSAGGAGSGAASASTANKTQTATFGLQSLNINDNLPIKAKPLTIRKQPLFEQPRLKSSQSSSNGQQKPPLLQLQNQRKSEPSARQPTENLPDTSPQHSPSSESSADETDRMVAPSITTSQQETSTSATSTTTTVTTSNIKERTGNGKPKLGRRVSFDPLALLLDASLEGELELVKKTAMQVANPSAANDEGITALHNAICAGHIDIVKFLVEFGCDVNAQDSDGWTPLHCAASCNNLSMVKFLVESGACLFASTLSDHETPAEKCEEDEEGFDGCSEYLYSIQEKLGILHNGDVYAVFSYEAQNGDELSFHVNEPLIVLRKGDDAENEWWWARNAAGEEGYVPRNLLGLYPRVPPHSPHFSD
Protein: Auxin efflux carrier component 2 (OsPIN2) (Q651V6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Acts as a component of the auxin efflux carrier. Involved in the basipetal polar auxin transport which contributes to the spreading growth of the tillers.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Auxin efflux carrier component 3a
Sequence:
MITGRDIYDVLAAIVPLYVAMFLAYGSVRWWGIFTPDQCSGINRFVAVFAVPLLSFHFISTNDPYSMNYRFLAADSLQKLVILAALAVWHNLLSRYRRNGGAAASLDWTITLFSLSTLPNTLVMGIPLLRAMYGDFSGSLMVQIVVLQSVIWYTLMLFLFEYRGAKALISEQFPPDVGASIASFRVDSDVVSLNGREALQADAEVGRDGRVHVVIRRSASASTTGGGGGAARSGVSRAYGASNAMTPRASNLTGVEIYSLQTSREPTPRASSFNQADFYAMFSGSKMASQMASPMAQHGGAGGRAQGLDEQVTNKFASGKAADPPSYPAPNPGMMPAPRKKELGGSNSNSNKELHMFVWSSSASPVSEANLRNAVNHAASTDFASAPPPAAVPVGGATPKGVSGSVTPAAKNGGGELEIEDGLKSPAAGLAAKFPVSGSPYVAPRKKGGGADVPGLAEAAHPMPPTSVMTRLILIMVWRKLIRNPNTYSSLIGLVWSLVSFRWNIQMPSIIKGSISILSDAGLGMAMFSLGLFMALQPKIISCGKTVATFAMAVRFLTGPAVIAATSIAIGLRGVLLHVAIVQAALPQGIVPFVFAKEYNCHPQILSTAVIFGMLIALPITILYYVLLGI
Protein: histone acetyltransferase (EC 2.3.1.48) (F4IDH2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNVQAHMSGQVSNQGTMSQQNGNSQMQNLVGGGSAPATGAGLGPSRVSPVDNDILKLRQAMRIRIFNILQQKQPSPADEASKAKYMDVARRLEEGLFKIANTKEDYVNPSTLEPRLASLIKGRQLNNYNQRHANSSSVGTMIPTPGLQHSGGNPNLMITSSGDATMAGSNNITTSAMNTGNLLNSGGMLGGNLSNGYQHSSSNFGLGSGGNMSSMSSQRNTGQMMPTPGFVNSSTNNNSNNGQSYLSVEASNNSGGFSTAPMMVPQTQQQQLRQDIGGQNSRMLQNHGSQMGVGLRPGMQQKLSNVSNSSINGGVGMNAKSVDSGTSYTNPIRNSQQAYDNLQRSGMQGDGYGTNNSDPFGSGNLYGAVTSVGMMTNTQNANTASFQAVSRTSSSLSHQQQQFQQQPNRFQQQPNQFHQQQQQFLHQQQLKQQSQQQQRFISHDAFGQNNVASDMVTHVKHEPGMENPSESIHSQTPEQFQLSQFQNQYQNNAEDRHAGSQILPVTSQSDMCTSVPQNSQQIQQMLHPHSMASDSVNGFSNLSVGVKTESGMRGHWQSQSQEHTQMSNSMSNERHIQEDFRQRMSGTDEAQPNNMSGGSIIGQNRVSTTSESLNPQNPTATTCRNGNGNRDPRFKNQQKWLLFLRHARHCKAPEGKCPDRNCVTVQKLWKHMDSCAAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVKAYLQQQANARSLARLKNETDAARSVNGGGISSDAVQTSAGAKSCTSPGADISGHLQPSLKRLKVEQSSQPVDVETESCKSSVVSVTEAQSSQYAERKDHKHSDVRAPSKYFEVKAEVSDFSVQTRPGFKDTKIGIAENIPKQRPVSQPDKQDLSDVSPMQETTKVEKEPESLKKENLAESTEHTSKSGKPEIKGVSLTELFTPEQVREHIRGLRQWVGQSKAKAEKNQAMEHSMSENSCQLCAVEKLTFEPPPIYCTPCGARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTILAEGTPMPKARLEKKKNDEETEEWWVQCDKCEAWQHQICALFNGRRNDGGQAEYTCPYCFIAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIPTAESLVIRVVSSVDKKLEVKPRFLEIFREDSYPTEFAYKSKVVLLFQKIEGVEVCLFGMYVQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKLRGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLYDHFFMQTGECRAKVTAARLPYFDGDYWPGAAEDLIYQMSQEEDGRKGNKKGMLKKTITKRALKASGQTDLSGNASKDLLLMHRLGETIHPMKEDFIMVHLQPSCTHCCILMVSGNRWVCSQCKHFQICDKCYEAEQRREDRERHPVNFKDKHALYPVEIMDIPADTRDKDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNACHLDIETGQGWRCEVCPDYDVCNACFSRDGGVNHPHKLTNHPSLADQNAQNKEARQLRVLQLRKMLDLLVHASQCRSAHCQYPNCRKVKGLFRHGINCKVRASGGCVLCKKMWYLLQLHARACKESECHVPRCRDLKEHLRRLQQQSDSRRRAAVMEMMRQRAAEVAGGSGINMRALNQGCHFPEEEEREQCQPSSQMTRVLRDSGLMGFGWLIF
Protein: Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31) (P30040)
Organism: Homo sapiens (Human)
Function: Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.
Subcellular location: Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Interaction partners:
- ERO1-like protein alpha
- ERO1-like protein beta
- Endoplasmin
- Cytochrome P450 2S1
- Calreticulin
- Endoplasmic reticulum chaperone BiP
- Protein disulfide-isomerase A4
- Cytochrome P450 2F1
- Heat shock 70 kDa protein 4
- Calnexin
Sequence:
MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYTGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQKKGAEKEEL
Protein: BcDNA.GH03163 (CIN85 and CD2AP related, isoform B) (CIN85 and CD2AP related, isoform H) (CIN85 and CD2AP related, isoform I) (Q9Y154)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTTTNSSNSSTTSVTTQQQKEQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASSSAGRKESFGSRDSLNDILSETGLPTGNVAAQRKSLENKNLDLTKPPGVGASVSIGQQRSSTSSATTSSATTVATGLTSSSVSKSMENMLDEKVKSPPPPVLSKKPSVPLKKTPTGGVPMTGNLLGGKKKNTEGKLTTAVSHDLADGLAASKMLSGANQLPESGAAGNVVIRRAATIAVEDTDFDRVERASILTDMRQGRVKAPKRRPPSAAINVLGESNNNSVYVNGSGMSGSGGAGSASELSEDGGAGGKTSDDNSTGEEPQLAKPKPREWEKKKAPWMEELKASQVTRKKTSPSVEPRGASVAERTSKLFAAEQAVSSNSSSITTKVQSSAVTSSMFVENSTTSSSVITSSSHTTTNDAIMSRSLSAAKVQTASSDEETRATRPNSLAIRNQRSVSPLVKSSNASSSQSQEEKPTSQLNNHQDASSSRVAQLEQRVDKLEGLVLNQQRTIEELVNALKSEAERVKILRSELDKYAQCVTQV
Protein: ATP-dependent RNA helicase SUV3, mitochondrial (OsSUV3) (EC 3.6.4.13) (Protein SUPPRESSOR OF VAR 3) (Q10D00)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner (By similarity). ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates (By similarity). Confers salinity and drought stress tolerances by maintaining both photosynthesis and antioxidant machinery, probably via an increase in plant hormones levels such as gibberellic acid (GA(3)), the cytokinin zeatin (Z) and indole-3-acetic acid (IAA).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8IYB8}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q9SMX1}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250|UniProtKB:Q8IYB8}.
Interaction partners:
- Os01g0841800 protein
- Os03g0129200 protein
- DIS3-like exonuclease 2
Sequence:
MAVAAALLRRRALYSALASPSWLHDTSSCYICSISGTHSLVNHPNLRLQRGYHNSGKFDLTDLTHPHIWYPNAREKKRNVFLHVGPTNSGKTHNALKRLEASSSGVYCGPLRLLAREVAQRLNKANVPCNLITGQEREEIEGAKHSSVTVEMADMTTEYQCAVIDEIQMVGCRSRGFSFTRALLGLCSDELHVCGDPAVVPLIQRILEPTGDVVTVQYYERLSPLVPLKTTLGSFSNIKAGDCVVTFSRRSIYMLKRRIEMGGKHLCSVVYGSLPPETRTKQATMFNDQDSNLNVLVASDAIGMGLNLNISRIIFSTLEKFDGICNRELTVAEIKQIAGRAGRYGSKFPVGEVTCLNSDHLPLLHSALKSPSPIIERAGLFPTFDVLSLYSRLHGTDFFQPILERFLDKAKLSPDYFIADCEDMLKVAAIVDELPLGLYDKYLFCLSPVDIRDDISTKGLIQFAENYAKKGIVRLKEIFTPGTLQVPKSHNQLKELESIHKVLELYVWLSFRLEDSYPDRELAASQKSICSMLIEEYLERSGWQQNGRKDFLQKPKRLHQEYDASQLRKYFQEIDVRSK
Protein: Erg251p (A0A1D8PLB5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Delta
- Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating
- 3-keto-steroid reductase ERG27
- Lanosterol 14-alpha demethylase
- Squalene epoxidase ERG1
- Delta
- C-22 sterol desaturase ERG5
- Sterol 24-C-methyltransferase
- C-8 sterol isomerase ERG2
- Squalene synthase ERG9
Sequence:
MEVLHQLTTNHTSSLSNLINNHPTSFSSILKEVDITNHSLTYIEKLWASYYIYMNNDILATGLLFFITHELMYFGRCLPWFIIDKTPWFNRYKIQPTKIPTNQEQWECFKTVLKQHFLVEALPIWLFHPVCAKLGITYDVPFPNWKIQAIQIAIFFICEDFWHFVFHSLFHQGWFYKNIHKVHHKYAAPFGLAAEYAHPVEVMALGVGTVGFPILYAYLATVYTNMPPLHLFTLTTWIVLRLFQAVDSHSGYDFPWSLNKFFPLWAGAAHHDEHHHYFIGNYASSFTLWDWLFQTECGTYARKRRERNSRASAESKHKKTL
Protein: Cell differentiation, Rcd1-like protein (Phytochrome interacting molecule 1) (Q9LXU1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transcription regulator
- Probable NOT transcription complex subunit VIP2
- Transcription regulator NOT2/NOT3/NOT5 family protein
- RNA binding
- RNA binding
- NOT2 / NOT3 / NOT5 family
- Carbon catabolite repressor protein 4 homolog 1
- CCR4-NOT transcription complex subunit 11
- Probable CCR4-associated factor 1 homolog 11
- AT5g35440/MOK9_2
Sequence:
MANLPPPLSMKSVALSGASSPSSSSNNDRKLSSAEQLILDLSNPELRENALHELSKKREIFQDLAPLLWHSVGTIPALLQEIIAVYPALSPPTMTPAQSNRVCNALALLQCVASHTDTRMLFLKAHLPLYLYAFLNTSSKSRPFEYLRLTSLGVIGALVKVDDTEVIRFLLQTEIVPLCLRTMENGSELSKTVATFIVQKVLLDDVGLEYMCTTAERFFALGRVLGNMVTSLAEGPSARLLKHIIRCYLRLTDNPRACDALGSCLPDLLRDATFSGCLYDDPPAMQWLQQLLHNVNVGGRAPQGLAHMFVN
Protein: Tubulin epsilon and delta complex protein 1 (Uncharacterized protein C14orf80 homolog) (Q3UK37)
Organism: Mus musculus (Mouse)
Function: Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability. May play a role in counteracting perturbation of actin filaments, such as after treatment with the actin depolymerizing microbial metabolite Chivosazole F (By similarity).
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:29459677}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:29459677}.
Interaction partners:
- Tubulin epsilon and delta complex protein 2
Sequence:
MRRRRSRVEGAARALPEAVAALSRCLPAGPSPEIFRRAKFDRPEAAPVLWQLLLRVLSPLAANNTWTDLAPEAQACVVKSALGSQGYPRSVLLQFPDGSSQGSRELLLALSWLLARGPLLEQLLAQTRVQLGDQLPQWEAPTSPGPPAPFVEPKSPVDLRLVEWLMGRLRFRWRCLISSQQEQCILLSKIHLYTQGCHSQQSLGHLSVAETEMLRDPESGQQLLQALESENIRLEAALEWRRRELVFWQWMDTVLDTCSPETPAVTSQPTFLPEISEGGLGELESVKQELQALQEELREVSEPRRAAWEARVGGLGQGPEWSNSRKALQEAVQQELAALQGSWEQSSTPGQPQRPHRLVRSKDGAPRPQGLQAAEVIRTLSAKEACLKKALHQLQRQCQQELARLAGALPGLIWILPPEH
Protein: Vesicle transport protein USE1 (USE1-like protein) (A0A8I6A1D9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}.
Interaction partners:
Sequence:
MAQAEGACHRPLATSRLELNLVRLLCRCESMAAEKREPDEWRLEKYVGALEDMLQALKVQASKPASEVISEYSRKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTAKERVPATKTVHLQSRARYTSEMRSELLGTESSGELEADMRKRVSVKGPRPADEKQSASELDLVLQRHQGLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKLESERLEQHAQKSVNWLLWAMLIVVCFVFISMILFIRIMPRLK
Protein: Anaerobic glycerol-3-phosphate dehydrogenase, A subunit, putative (Q72AQ2)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Anaerobic glycerol-3-phosphate dehydrogenase, B subunit, putative
- Glycerol kinase
- Glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate dehydrogenase [NAD
- Anaerobic glycerol-3-phosphate dehydrogenase, subunit A, truncation
- Glycerol-3-phosphate acyltransferase
- 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative
- phosphoenolpyruvate--glycerone phosphotransferase
- DAK2 domain protein
- Diacylglycerol kinase
Sequence:
MQTQVLIIGAGATGTGVARDLALRGVDCILIDQRDVNAGASGGNHGLLHSGGRYVFTDPHAAAECKAEGDILKRIAPQCIEETGGYFVAVEGDDPAYASDFPGYCAKAGVPCREVDAHEARRNEPAIAESTFAVYEVEDASVDPFKLSLENVADAGRHGGRYLRYTRVLGFDMERGRIVAARVEDMRSGREYRIVADEYVVAAGAWSGGITAMAGCHVDIVYAKGTLLVTQTRMAHRVINRLRTPGDGDILVPGGTVSVLGTTSLRVESPDDVRPTVAEVDVNINEGMGMVPSLADARFIRAYAGVRPLVRSGKPSGSDRAASRGFVLLDHEEDGVHNLVTIAGGKLTTYRLMAERAADLVCERLGVSAPCLTAVRPISPSDEAEWAEPGVLQKQNWWRNHDRDDYLLCECEIVPKSGVDSIIATFKDEAEPPRLLAIGLRSRVGKGSCQGAFCGARITAHMHDRRIIEGREGLDGLREFLGARWKGQRPILWGAQFNQAELKEALYFGLVGMELE
Protein: Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog) (Q53FZ2)
Organism: Homo sapiens (Human)
Function: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms (By similarity).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11772874}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q3UNX5}.
Interaction partners:
- Short-chain specific acyl-CoA dehydrogenase, mitochondrial
- Peroxisomal bifunctional enzyme
- Hydroxysteroid dehydrogenase-like protein 2
Sequence:
MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWKTI