wanglab/gogpt-training-data huggingface dataset:
Protein: 56 protein (DNA helicase-primase complex () component) (DNA replication protein) (P88992)
Organism: Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68)
Interaction partners:
Sequence:
MARYHSNSCLVSPDTVRCIFSTDIDVIDAVVNLITHEGATEYKFTSLIHDCFSISGLKNISSISMCLPLNRPNKEKKYFELFKVDISCDDAKQFLFNGRPLTSGQVASCLDYSHLKAQILPILKLIMSLDNRGEKEGTFLEMVRWYQSKLINFLRKLLKTTSSTQWFITTFGQDDLTFTLVIASYYFYKHACTVETLMHLARLFCGELGHSLIDVSSLQELGLFFSSSSILDSVPLFAEYVETKLNIDTLENEKIDQMINEIRGGLLLSNKDIVQFVYLAFYACFNKTAFLEFIGKTSPDNINTYSSEILHLKLCDEFLDKMSSYYNKEKYIHTHLLTKVVRVPGASLGSYGDTPGTLQAWFGQTSDLTALFDSINEDFPFYSSESSLKELLKLASLSPQELDNPKDILFPEKPICPTYRSEFKNKTYFVMVATDSIEDYWKKHVIFPHSINLDELTDVRITELLTYCVNGCTSNTVEDNLMVSRHEYFNPHLPIYNVILDFDLPVEVPGYKIEDIYNLCLQIRQDIITVLSTILNLEMPPSHPVYFFKSECNSDIYMEPRPFCTCSKKIGLRIITPLPMRHAIVGATPLITLARVINRTIRLNKRVCELFPSISSTEFLFDTGIYSQGRCIRLPHTYKFTSTGLPERLLKLFVCHPFPDKTSYVKNSFVLTNLLYHSTSEDLRSGDYNLILDIRDKDEDFLSCKTVASLPKNSLDIDKLEDILGCPVQSWIDTTLWPLFCEQLVKYLPQKNANELNNISFNVVSNNMLQLKPRRGPGFSCLTHQHRTKSHNVRLFITLGKFSRDVITATLMSQCFANKCNNNKPVTHCTVHARV
Protein: Carbonic anhydrase (EC 4.2.1.1) (Q6PFU7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MADHWGYDKHNGPDKWGESYPIANGSRQSPIDIKSSTTTYDEKLTPLKLKYDPSTSLDIQNNGHSFQVSFVDDQNSSTLTGGPVTGTFRLKQFHFHWGSADDKGSEHTVNGKCYPAELHLVHWNTKYPSFKDAVDKPDGLAVVGIFLKIGADNPKLQKILDAMDAIKSKGKQTPFPNFDPSVLLPSSLDYWTYLGSLTTPPLLESVTWIVCKQSISVSSAQMKRFRSLLFSGDGEKACCMVNNYRPPQPLKGRVVRASFK
Protein: Complexin-4 (Complexin IV) (CPX IV) (Q80WM3)
Organism: Mus musculus (Mouse)
Function: Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release.
Subcellular location: Synapse {ECO:0000269|PubMed:15911881, ECO:0000269|PubMed:22694764}. Cell membrane {ECO:0000269|PubMed:15911881}; Lipid-anchor {ECO:0000269|PubMed:15911881}. Note=Enriched at the synaptic terminal. {ECO:0000269|PubMed:15911881}.
Interaction partners:
- Complexin-1
- Complexin-2
- Vesicle-associated membrane protein 1
- Protein ERGIC-53
- Vesicle-associated membrane protein 2
Sequence:
MAFFVKNMISNQVKNLGFGGGSEEKKEEGGTSDPAAAKGMTREEYEEYQKQMIEEKMERDAAFTQKKAERACLRVHLRDKYRLPKSEMDETQIQLAGDDVDLPEDLRKMVDEDQDEEEEKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQSAEQKCSVM
Protein: Ranatuerin-2SEc (P85053)
Organism: Lithobates sevosus (Dusky gopher frog) (Rana sevosa)
Function: Mast cell degranulating peptide. Causes histamine release from rat peritoneal mast cells in vitro. Has antibacterial activity against the Gram-negative bacterium E.coli K12 and Gram-positive bacterium M.luteus NCT C2665.
Subcellular location: Secreted {ECO:0000269|PubMed:16386333}.
Interaction partners:
Sequence:
GIMDTIKDTAKTVAVGLLNKLKCKITGC
Protein: Saposin A (Q54C60)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Saposin B-type domain-containing protein
Sequence:
MYKINIYLLIFTIILASLFATSKSLVVQKNVGEIDNNQCQICELLVKDIIEGLTANQSVEVIEHGLNLICDHIPLHVRVCKQFVDSNFQKIVQFIENHDDPQEICEKCGVCGSSDEYNKIDTRYFPQHNQHKRHLKKQNSIKN
Protein: Myosin-4 protein (DUF641) (O22146)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g09670
- Uncharacterized protein
- At1g44770
- Elongation factor
- Grap2/cyclin-D-interacting protein
- Haloacid dehalogenase-like hydrolase family protein
- Spire, putative
- At1g05410/T25N20_5)
- Uncharacterized protein At2g29880
- At3g50040
Sequence:
MLPSGLKETQLRESNNNQKVHPQPMEESINQNPEAMEALISNLFGNISSLKSAYIELQSAHTPYDPEKIQAADKVVISELKNLSEMKHFYRENNPKPVCVSPQDSRLAAEIQEQQSLLKTYEVMVKKFQSEIQNKDSEITQMLQKIEEANQKRLKLEKNLKLRGMSTNEGSNGDGNMQFPDLTTELYVSTYEAAAKAVHDFSKPLINMMKAAGWDLDSAANSIEPDVVYAKRPHKKYAFESYICQRMFSGFQQKNFSVNSESAAVMANDDTDTFFRQFLALKDMDPLDALGTNPDSNFGIFCRSKYLLLVHPKMEASFFGNLDQRDYVTGGGHPRTAFYQAFLKLAKSIWILHRLAYSFDPAAKIFQVKKGSEFSDSYMESVVKNIVVDEKEENPRVGLMVMPGFWIGGSVIQSRVYVSGVKVLE
Protein: 1,4-alpha-glucan-branching enzyme 1, chloroplastic/amyloplastic (EC 2.4.1.18) (Starch branching enzyme I) (Q41058)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: Catalyzes the formation of the alpha-1,6-glucosidic linkages in starch by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. May preferentially transfer short chains during branching. Responsible for the synthesis of about 75% of the amylopectin found in the starch granules of mature embryos.
Subcellular location: Plastid, chloroplast. Plastid, amyloplast {ECO:0000305}.
Interaction partners:
Sequence:
MVYTISGIRFPVLPSLHKSTLRCDRRASSHSFFLKNNSSSFSRTSLYAKFSRDSETKSSTIAESDKVLIPEDQDNSVSLADQLENPDITSEDAQNLEDLTMKDGNKYNIDESTSSYREVGDEKGSVTSSSLVDVNTDTQAKKTSVHSDKKVKVDKPKIIPPPGTGQKIYEIDPLLQAHRQHLDFRYGQYKRIREEIDKYEGGLDAFSRGYEKFGFTRSATGITYREWAPGAKSAALVGDFNNWNPNADVMTKDAFGVWEIFLPNNADGSPPIPHGSRVKIHMDTPSGIKDSIPAWIKFSVQAPGEIPYNGIYYDPPEEEKYVFKHPQPKRPQSIRIYESHIGMSSPEPKINTYANFRDDVLPRIKKLGYNAVQIMAIQEHSYYASFGYHVTNFFAPSSRFGTPEDLKSLIDRAHELGLLVLMDIVHSHSSNNTLDGLNMFDGTDGHYFHPGSRGYHWMWDSRLFNYGSWEVLRYLLSNARWWLDEYKFDGFRFDGVTSMMYTHHGLQVSFTGNYSEYFGLATDVEAVVYMMLVNDLIHGLFPEAVSIGEDVSGMPTFCLPTQDGGIGFNYRLHMAVADKWIELLKKQDEDWRMGDIVHTLTNRRWLEKCVVYAESHDQALVGDKTLAFWLMDKDMYDFMALDRPSTPLIDRGIALHKMIRLITMGLGGEGYLNFMGNEFGHPEWIDFPRGEQHLPNGKIVPGNNNSYDKCRRRFDLGDADYLRYHGMQEFDRAMQHLEERYGFMTSEHQYISRKNEGDRVIIFERDNLVFVFNFHWTNSYSDYKVGCLKPGKYKIVLDSDDTLFGGFNRLNHTAEYFTSEGWYDDRPRSFLVYAPSRTAVVYALADGVESEPIELSDGVESEPIELSVGVESEPIELSVEEAESEPIERSVEEVESETTQQSVEVESETTQQSVEVESETTQ
Protein: Activated protein kinase c receptor (Q4Q7Y7)
Organism: Leishmania major
Interaction partners:
- Ribosomal protein S16
- Putative 40S ribosomal protein S17
- Putative 40S ribosomal protein S23
- 40S ribosomal protein S3
- Small ribosomal subunit protein eS8
- 40S ribosomal protein S24
- 40S ribosomal protein S7
- Small ribosomal subunit protein uS2
- 40S ribosomal protein S5
- Putative 40S ribosomal protein S15
Sequence:
MNYEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPDRHSVDSDYGLPNHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQLFKINVESPINQIAFSPNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSISDAE
Protein: AFG3 like matrix AAA peptidase subunit 2, isoform A (EC 3.4.24.-) (SD01613p) (Q8T4G5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Paraplegin, isoform A
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- Complex I assembly factor TIMMDC1, mitochondrial
- Caseinolytic protease chaperone subunit, isoform C
- Prohibitin 1
- Prohibitin
- ATP-dependent Clp protease proteolytic subunit
- Mitochondrial ribosomal protein L2
- Lon protease homolog, mitochondrial
- Mitochondrial-processing peptidase subunit alpha
Sequence:
MAFRLLGTAKTMAGMMRRNYTAGSLPGKGQRTHMGATGAGVYILPTELSPLLRYVVKQIQLLCKKPPKGFEKYFEAGGKSSGQPKGSVGDKKPPAGSSKSASEKPSTSTPASVKPSRSQTDAKSDWNFGMFSNSSRGPAGKGGNSLGGRPLGENGGGGDRERWILLGAIGAVVLVGSFAFFEMGYKEISWKEFVNSYLSKGVVEKLEVVNKKWVRVRLQQNSNSGSGVLWFNIGSVDSFERNLEAAQTEQGTESINFVPVIYRNEVEAASLTGLLPTLLIIGFLVYMMRKSADMMGGGRGRKGGGLFGGVMQSTAKLTNPNEIGVGFKDVAGCEEAKIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKTSLDKNELSRKMAALTPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERVIAGMEKKTNVLAPEEKRTVAHHEAGHAVAGWFLEHADPLLKVSIIPRGKGLGYAQYLPKDHYLLSKEQLFDRMCMTLGGRVAEELFFNRITTGAQDDLKKITDIAYSQVVRFGMNEKVGQVSFDVGQAGDPVFSKPYSEDTAQLIDNEVRSIIKCAHEATTSLLTKHKENVQKVAERLLQNEVLSRDDMIELLGPRPFKEKSTYEEFVEGTGSFEEDTTLPEGLKSWNKEKERTEPLDAGSTPSSPPTKPVTAQSS
Protein: U3 small nucleolar ribonucleoprotein protein MPP10, putative (Q57W95)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- KRR1 small subunit processome component
- Bms1-type G domain-containing protein
- U3 small nuclear ribonucleoprotein
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- U3 small nucleolar RNA-associated protein 6 N-terminal domain-containing protein
- U3 small nucleolar RNA-associated protein 18
- HEAT repeat-containing protein 1
- H/ACA ribonucleoprotein complex subunit 2
- AATF leucine zipper-containing domain-containing protein
- BING4 C-terminal domain-containing protein
Sequence:
MVTAMANTKKKVKASVPEGATSSLKTEDMTVPRDQTSTSKLPISRVSRRLGSVQAKLDGGPDVFLSSRQGGSDLTRECLASLYKLASSMHSRQLTYYSKSLETSRARHVTLEQIWGQMSMLLPPVFRRLRENVRRAQKMYGCGETQGSQVKQRSSDNKSGSGMHNGKKDKEDNREDDVDASSAHTSQLNESDLDNEIAELLAKQREARKRRKRNAADDSWRYVFGKGDGEEDADAEGGEGWSEGEEDREDGSESGNDNEMDALRGRRKGSRDVTAPGDFGGDGEDADDEEKQLAQEELEALKEMYGEDFVPNEEDEECEYDDGEGDLGDDDQLLEEDLKWDDPSAVFSGKDAALKGEGEGWYDGEDDILAETGQEGDMGDDMEDDAALNDPSLTELQRERLRERRFVEKLEQARLYSTQWAMSGEVSGSNRPRDALLDEALDFEYAMKAVPVITEGFTAKLEDRIRRRIVDNNYDDVQRRTALSTPSDLASMSRRDDASAKDSEKARMSLMDLYEKEYLDRVRRAEESAAGGSAAESAEPLTEIEKDELRAIHMWRRLAQHLDALSNFHYTPKPVQEDLSARVRAVEGQAPAITFETVGNFATTREAALAPQDLYRGSDRKFADVGVNELQPHERRALRRAKKEQVSTSQAIKEKHKERAKRAKEQLRKAAA
Protein: Tumor necrosis factor receptor superfamily member 13C (B-cell-activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD antigen CD268) (Q96RJ3)
Organism: Homo sapiens (Human)
Function: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Subcellular location: Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
Interaction partners:
- Tumor necrosis factor ligand superfamily member 13B
- TNF receptor-associated factor 3
- Tumor necrosis factor receptor superfamily member 13B
- Tumor necrosis factor receptor superfamily member 5
- Tumor necrosis factor receptor superfamily member 3
- CD40 ligand
- TNF receptor-associated factor 2
- Tumor necrosis factor ligand superfamily member 13
- Tumor necrosis factor receptor superfamily member 17
- B-lymphocyte antigen CD19
Sequence:
MRRGPRSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKPAGASSPAPRTALQPQESVGAGAGEAALPLPGLLFGAPALLGLALVLALVLVGLVSWRRRQRRLRGASSAEAPDGDKDAPEPLDKVIILSPGISDATAPAWPPPGEDPGTTPPGHSVPVPATELGSTELVTTKTAGPEQQ
Protein: Transcriptional regulator SdrP (Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein SdrP) (CRP/FNR superfamily protein SdrP) (Oxidative stress-responsive transcriptional activator SdrP) (Stationary phase-dependent regulatory protein) (SdrP) (Q5SIL0)
Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Function: Activates transcription. The consensus DNA-binding site of this transcriptional regulator is 5'-WWGTGAN(5-7)ACACWW-3' in which W is A or T and N is G, A, T or C. Regulated genes include those encoding proteins involved in nutrient and energy supply, redox control and polyadenylation of mRNA. Also regulates genes involved in oxidative stress response such as genes encoding manganese superoxide dismutase and catalase, and genes encoding a protein involved in nucleotide excision repair of damaged DNA and putative proteins involved in redox control, protein degradation and transcriptional regulation.
Interaction partners:
Sequence:
MTQVRETVSFKAGDVILYPGVPGPRDRAYRVLEGLVRLEAVDEEGNALTLRLVRPGGFFGEEALFGQERIYFAEAATDVRLEPLPENPDPELLKDLAQHLSQGLAEAYRRIERLATQRLKNRMAAALLELSETPLAHEEEGKVVLKATHDELAAAVGSVRETVTKVIGELAREGYIRSGYGKIQLLDLKGLKELAESRGQGR
Protein: Fpg1p (A0A1D8PPQ0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Dephospho-CoA kinase
- DNA polymerase gamma
- Endonuclease III homolog lyase)
Sequence:
MPEVAEVSHVCALLKRNILGFRITKVNLLHDPLLFPVLKNTNDAEKELNKMRKVLTNAVVTSVGRHGKYFWIRLNNHNTTNVLLMHFGMTGMIKLRNVHSHLAFMENGGDKKALEKLERFRYKDSRIKPDVEVKQEWPPRFTKFNMELENNDKKLEFAFSDPRRLARVRLLSGLEVSTDESLLKLSPLNALGPDYSKPEVPPKESEPFVFGDPDSDNHGRARLSIDEFSALILSKKKPIKSLLLDQTYFAGVGNWVADEVLFQAHIHPNEILSSKISKDLEYVHPVIQQLYDSLIYVCEEAVRVEGDVAKFPDDWLMLHRWGKGRKEKRKTPNGYILDHITVGGRTSCYCPELQRLIKVETATTTKRRKVKR
Protein: Chemotaxis protein CheW (Coupling protein CheW) (P39802)
Organism: Bacillus subtilis (strain 168)
Function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase CheA; they are both necessary for efficient chemotaxis.
Subcellular location: Cytoplasm.
Interaction partners:
- Chemotaxis protein CheA
- Chemotaxis protein CheV
- Methyl-accepting chemotaxis protein McpB
- Methyl-accepting chemotaxis protein McpC
- Chemotaxis protein CheY
- Protein-glutamate methylesterase/protein-glutamine glutaminase
- Chemotaxis protein methyltransferase
- Flagellar motor switch phosphatase FliY
- CheY-P phosphatase CheC
- Methyl-accepting chemotaxis protein McpA
Sequence:
MTAEIKTGEKMIVFMVNGKEYAISVTQVKSIEKWQKPTRVPGVEPYICGVINLRGVVTPVIDLRKRLNLPEYEITDETRIIIIAYRDIEVGWIVDEANDVITVHESEIESAPEGVQKDTDVSIEQIVKQENRLLNIIDANAVLDKESSQSAVPDQA
Protein: Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4) (Q8L838)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for normal Golgi function.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9H9E3}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9H9E3}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9H9E3}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 2
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 7
- Conserved oligomeric Golgi complex subunit 3
- Vacuolar protein sorting-associated protein 54, chloroplastic
- Vacuolar protein sorting-associated protein 53 A
- Proline-rich family protein
Sequence:
MPEIEQDDAAAETVDSSTVKFGTPEALEYVRSLTDVGAMTRLLHECIAYQRSLDSDLDTLLSQRTELDRNLVQLQRSAEILDIVKADADHMLGNVRSTCDLADQVSGKVRELDLAQSRVNVTLSRIDAIVERGNCIEGVKTALESEDYESAAKFVQRFLQIDLQYKDSGSDQSEQLHASKEQLEGIAKKKLLAAIDQRDHPTILRFVRLYSPLGMETEGLQLYVGYLKKVIALRGRMEYENVVELMEQGLGQVNFVGCLTNLFKDIVMAIEENDEILRGLCGEDGVAYAICELQEECDLRGSLILKKYMDFRKLAILASDINNSPNLNILPGGASEGPDPREVELYVEEILSLMQLGEDYTEFMVSKIKSLTSVDPELLPTATKAFRNKSFSKAIQDVTRYYVILEGFFMVENVRKAIRIDEHVPDSLTTSMVDDVFYVLQSCLRRAISTSNISSVIAVLSYAGSLLGNDYHEALQQKIREPNLGARLFLGGIGVENTGTEIATALNNMDVSCEYILKLKHEIEEQCTEVFPAPADRERIKSCLSELGELSSTFKQLLNSGMEQLVATVTPRIRPVLDTVATISYELTETEYAENEVNDPWVQRLLHSVETNAAWLQPLMTSNNYDSFLHLIIDFIVKRLEVIMMQKRFSQLGGLQLDRDTRALVSHFSGMTQRTVRDKFARLTQMATILNLEKVSEILDFWGENSGPMTWRLTPAEVRRVLGLRVEFKPESIAALKL
Protein: Ammonium transporter 2 member 5 (Ammonium transporter 2;5) (MtAMT2;5) (A0A072VHJ1)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Involved in ammonium transport (By similarity). May be involved in arbuscular mycorrhizal (AM) symbiosis with AM fungi (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9M6N7}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Nitrogen regulatory protein P-II
- Katanin p80 WD40 repeat-containing subunit B1 homolog
- Katanin p80 WD40 repeat-containing subunit B1 homolog
Sequence:
MSGVPFPSNLLPSPSSPEWLSKADNAWQLMAATLVGMQSVPGLIILYGGAVKKKWAVNSAFMSLYAFACVFFCWVFWAYRMSFGDTLFPFWGKPALALDEKYLFKQAFLGAFPNATMIYFQCVFAAITLILIAGAVLGRMNFYAWMMFVPLWLTFSYTFTAFSIWSTNGFLAKMGIIDYSGGYVIHLSSGVAGFTAAYWVGPRLNKDRERFPPNNLLLMLAGAGLLWMGWTGFNGGDPYSVGLDASLAVLNTHACTATSLLTWVFLDVIFFRKPSVIGAVQGMITGLVCITPAAGVVQGWAALIMGLFSGSIPWFTMMVIHKRSKLLQKVDDTMAVLHTHAIAGSLGGILTGLFAEPKLNSLFYGVYNKYVGLFYGIQMNMASTGRRQIGIQLLGILFVIFVNVVSTSLICLFIRLFVPLRMSEEDMEIGDEAAHGEEAYAIWGQGDKHENSNSKYGSSLYEDVEVAATTKNKRGSQIEMM
Protein: Nuclear hormone receptor family member nhr-43 (Q18299)
Organism: Caenorhabditis elegans
Function: Ligand-activated transcription factor (By similarity). Positively modulates expression of homeobox protein lin-39, perhaps by binding to the sequence motif 5'-TGAC-3' in regulatory regions of the lin-39 gene, acting in the embryo, and also in the vulval lineage.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- CCDC92/74 N-terminal domain-containing protein
- HMG box domain-containing protein
- Bursicon subunit alpha
Sequence:
MISGPFLHFDPTVPLQTVMIGHPATSPLSLPSSSSSPTVADPSNIHCRVCERRYDGSQHFGIDICRACAAFFRRSVAVKKTFVCRRGTNKCELNTVSRKTTCQKCRWMRCLLVGLNVDAVVGRRSPDHVKTTSRDESVKKEDEESDTGSEGKSCEDMDVSHPIEQFQQQISFSVHRPIPTIGNPNIYTTRASLINKVLINYNEFTKSRLDVELSLKHMQQDSKVFGSTGIPIVPATREIISEIYQKQFGLLHIFLKNTFDEYAECDVQEQKRICAMFYPVLWEIESCYWTYRNMPVQPEYETLMMCTQTTYIDSKNVRYWLGNTTGLNESDIQAVEARLENLLTKARNLVLEPMHKLIIKEFEFITLLALNIWAPRNHRGCVSEDRAEQVRDALFDDLHYLYCDGLKIDKYSSRMGEMMCLHTEVQNADMSSTIKNILFSDLNAYLYSI
Protein: Uncharacterized protein YdaQ (P76057)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Double-strand break reduction protein
- Endodeoxyribonuclease toxin RalR
- Prophage integrase IntR
- Killing protein KilR
- Protein RecT
- tRNA-cytidine
- Exodeoxyribonuclease 8
Sequence:
MAQVIFNEEWMVEYGLMLRTGLGARQIEAYRQNCWVEGFHFKRVSPLGKPDSKRGIIWYNYPKINQFIKDS
Protein: SET binding factor 1 (H0Y5W8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
VVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGERRGQVPCRSVWEYVDRLSKRTPVFHNYMYAPEDAEVWDFYTEETLAEGPPYDWELAQGPPEPPEEERSDGGAPQSRRRVVWPCYDSCPRAQPDAISRLLEELQRLETELGQPAERWKDTWDRVKAAQRLEGRPDGRGTPSSLLVSTAPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSGSRQAARRSTSTLYSQFQTAESENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRVDTECKGVIDLAEVEAVAPGTPTMGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSDA
Protein: Growth hormone-binding protein (Homologous to FPV ORF4) (SORF2) (Q69283)
Organism: Gallid alphaherpesvirus 2
Interaction partners:
Sequence:
MQRQTGHMEDKKRTGLESQGTENAFSDGRDGKDGLLHEGINEPILIPSTIADLEGIRELVRKFRGRLLPFEKCPDFCLRIGGLEASFHKGQEELLEYCEALYLPQPVKMEIVGIVDDVPCLATGMQLLILVAEGGEVYAYEEDTLHKLATSFSEFLEIGVKSLGREVYHCGEYIEQVVH
Protein: At1g64385 (Transmembrane protein) (Q8GUH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- AAA-ATPase At5g57480
- Transducin/WD40 repeat-like superfamily protein
- 2-oxoglutarate
- Uncharacterized membrane protein At3g27390
- RING-type E3 ubiquitin transferase
- ATP-dependent protease La
- At5g01015
- Phosphorylase superfamily protein
- At4g24340
- ARM repeat superfamily protein
Sequence:
MEVNLVLLLCIALIFVADTKVDGEAQVVVSNSNLTDTRFGGGSENVTDSSSKSIITIDHSKNSTNDDDTQLGDGSKMIGSDSSKSDQGKIASDESDKEEEEAVSKNSSRKKQGFHGEECDPSNMCIDDEHEFSACLRVPGNDAPHLSLLIQNKGKRALIVTITAPVFVRLEKDKVQLLQNEDIKVKVSIKKGGSNDSAIVLASSKGRCRLELKDLAAAAHETESDDTVSVSRPSILNISSRTLIVIIMISFLVLSLVIIPVIIHVYKNKSRGNNKYQRLDMELPVSNPALVTKSDQESGDDGWNNNWGDDWDDENGGGDEEQPNTPVLPLTPSLSSRGLAPRRLSKEGWKD
Protein: Suppressor of cytokine signaling 2 (SOCS-2) (O35717)
Organism: Mus musculus (Mouse)
Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O14508}.
Interaction partners:
- Elongin-C
- Elongin-B
- Cullin-5
- Tyrosine-protein kinase JAK2
- Insulin receptor substrate 1
- Suppressor of cytokine signaling 1
- Suppressor of cytokine signaling 3
- Growth hormone receptor
- Signal transducer and activator of transcription
- Insulin receptor substrate 2
Sequence:
MTLRCLEPSGNGADRTRSQWGTAGLPEEQSPEAARLAKALRELSQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPTLQHFCRLAINKCTGTIWGLPLPTRLKDYLEEYKFQV
Protein: Glycogen phosphorylase (EC 2.4.1.1) (P0AC86)
Organism: Escherichia coli (strain K12)
Function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Interaction partners:
- Glycogen synthase
- 1,4-alpha-glucan branching enzyme GlgB
- Glycogen debranching enzyme
- Glucose-1-phosphate adenylyltransferase
- Phosphoglucomutase
- 4-alpha-glucanotransferase
- Cytoplasmic alpha-amylase
- Periplasmic alpha-amylase
- Phosphocarrier protein HPr
- UTP--glucose-1-phosphate uridylyltransferase
Sequence:
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDRTIKEYADHIWHIDPVRL
Protein: Aminoaldehyde dehydrogenase BADH (EC 1.2.1.-) (4-trimethylammoniobutyraldehyde dehydrogenase BADH) (EC 1.2.1.47) (Aminobutyraldehyde dehydrogenase BADH) (EC 1.2.1.19) (Betaine aldehyde dehydrogenase) (SoBADH) (EC 1.2.1.8) (P17202)
Organism: Spinacia oleracea (Spinach)
Function: Dehydrogenase innvolved in glycine betaine biosynthesis. Metabolizes and detoxifies aldehyde products of polyamine degradation to non-toxic amino acids (Probable). Catalyzes the oxidation of betaine aldehyde to glycine betaine. Catalyzes the oxidation of 4-aminobutanal and 3-aminopropanal to 4-aminobutanoate and beta-alanine, respectively.
Interaction partners:
Sequence:
MAFPIPARQLFIDGEWREPIKKNRIPVINPSTEEIIGDIPAATAEDVEVAVVAARRAFRRNNWSATSGAHRATYLRAIAAKITEKKDHFVKLETIDSGKPFDEAVLDIDDVASCFEYFAGQAEALDGKQKAPVTLPMERFKSHVLRQPLGVVGLISPWNYPLLMATWKIAPALAAGCTAVLKPSELASVTCLEFGEVCNEVGLPPGVLNILTGLGPDAGAPLVSHPDVDKIAFTGSSATGSKVMASAAQLVKPVTLELGGKSPIVVFEDVDIDKVVEWTIFGCFWTNGQICSATSRLLVHESIAAEFVDKLVKWTKNIKISDPFEEGCRLGPVISKGQYDKIMKFISTAKSEGATILYGGSRPEHLKKGYYIEPTIVTDISTSMQIWKEEVFGPVLCVKTFSSEDEAIALANDTEYGLAAAVFSNDLERCERITKALEVGAVWVNCSQPCFVQAPWGGIKRSGFGRELGEWGIQNYLNIKQVTQDISDEPWGWYKSP
Protein: Probable CCR4-associated factor 1 homolog 2 (EC 3.1.13.4) (Q9S9P2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- At2g41950/T6D20.26
- Transcription regulator
- Transcription regulator NOT2/NOT3/NOT5 family protein
- Carbon catabolite repressor protein 4 homolog 1
- Probable NOT transcription complex subunit VIP2
- NOT2 / NOT3 / NOT5 family
- Cell differentiation, Rcd1-like protein
- Cell differentiation, Rcd1-like protein
- Cell differentiation, Rcd1-like protein
- CCR4-NOT transcription complex subunit 11
Sequence:
MSQAPNPEEEDDTIEIREVWNHNLEQEMALIEQSIDDFPYVAMDTEFPGIVCKTVTANPNPNPYSIHYEYNYDTLKANVNMLKLIQLGLTLSDEKGNLPTCGTNKQCIWQFNFREFNVISDMFALDSIELLRKSAIDLEKNNECGVDAKRFAELLMGSGVVLNDKIHWVTFHCGYDFGYLLKLLSGKELPEEISDFFDQMEKFFPVVYDIKYLMGFCTNLYGGLEKIAELLGVKRVGISHQAGSDSLLTLRTFIKMKEFFFTGSLLKYSGFLFGLDNPRLLTGSKN