wanglab/gogpt-training-data huggingface dataset:
Protein: Capsid protein (O56129)
Organism: Porcine circovirus 2 (PCV2)
Function: Self-assembles to form the virion icosahedral capsid with a T=1 symmetry. This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents. Essential for the initial attachment to heparan sulfate moieties and chondroitin sulfate B of the host cell surface proteoglycans. After attachment, the virus is internalized in a clathrin-, caveolae- and dynamin-independent, actin and Rho-GTPase-mediated pathway and traffics to the nucleus. The capsid protein binds and transports the viral genome and Rep across the nuclear envelope (By similarity).
Subcellular location: Host nucleus {ECO:0000269|PubMed:11414809, ECO:0000269|PubMed:29292065}. Virion {ECO:0000305}.
Interaction partners:
Sequence:
MTYPRRRYRRRRHRPRSHLGQILRRRPWLVHPRHRYRWRRKNGIFNTRLSRTFGYTVKATTVRTPSWAVDMMRFNIDDFVPPGGGTNKISIPFEYYRIRKVKVEFWPCSPITQGDRGVGSTAVILDDNFVTKATALTYDPYVNYSSRHTIPQPFSYHSRYFTPKPVLDSTIDYFQPNNKRTQLWLRLQTSRNVDHVGLGTAFENSIYDQDYNIRVTMYVQFREFNLKDPPLKP
Protein: Matrin-3 (P43243)
Organism: Homo sapiens (Human)
Function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs. May bind to specific miRNA hairpins.
Subcellular location: Nucleus matrix.
Interaction partners:
- TAR DNA-binding protein 43
- Non-POU domain-containing octamer-binding protein
- Splicing factor, proline- and glutamine-rich
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoproteins C1/C2
- RNA-binding protein 14
- Heterogeneous nuclear ribonucleoprotein M
- RNA-binding protein FUS
- Heterogeneous nuclear ribonucleoprotein H
- Heterogeneous nuclear ribonucleoprotein K
Sequence:
MSKSFQQSSLSRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET
Protein: Small hydrophobic protein (Small protein 1A) (Q77YB1)
Organism: Human respiratory syncytial virus A (strain A2)
Subcellular location: Host Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00024014}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00024014}. Host cell membrane {ECO:0000256|ARBA:ARBA00004336}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004336}. Host endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004641}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004641}. Virion membrane {ECO:0000256|ARBA:ARBA00004208}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004208}.
Interaction partners:
Sequence:
MENTSITIEFSSKFWPYFTLIHMITTIISLLIIISIMIAILNKLCEYNVFHNKTFELPRARVNT
Protein: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (MmPDE8) (EC 3.1.4.53) (O88502)
Organism: Mus musculus (Mouse)
Function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling. Protects against cell death induced by hydrogen peroxide and staurosporine.
Interaction partners:
- Deoxycytidine kinase
- High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- Adenosine kinase
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
- GTP:AMP phosphotransferase AK3, mitochondrial
- Adenine phosphoribosyltransferase
- Adenylosuccinate lyase
- Adenylate cyclase type 6
- Adenylate cyclase type 5
Sequence:
MGCAPSIHTSENRTFSHSDGEDEDVDVDVPGPAPRSIQRWSTAPGLVEPQPRDNGASKVSVADVQFGPMRFHQDQLQVLLVFTKEDSQCNGFHRACEKAGFKCTVTKEVQTVLTCFQDKLHDIIIIDHRYPRQMDAETLCRSIRSSKFSENTVIVGVVRRVDKEESSLMPFLAAGFTRRFIENPNVMACYNELLQLACGEVRSQLKLRACNSVFTALEKSQEAIEITSEDHIIQYANPAFESTMGYQSGELIGKELAQVPINEKKGDLLDAINSCVTVDKEWQGVYHTQKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKVETTTECVQTDSQTDNQAGKHKDRRKHSMDAKAVSSRTSDVSSQRRHSSLARIHSMMIEAPITKVINIINAAQENSPVPVTEALNRVLDILRTTELYSPQFNAQDDPHATDLVGGLMSDGLRRFSGNEYILATKNLPPLSNNLATPVSLHDVPPRIALAIENEEQWDFDIFELEVATQNRPLIYLGLKTFARFGMCEFLQCSETTLRSWFQMIESNYHSSNPYHNSTHAADVLHATAYFLSRDKIKETLDRIDEVAALIAATVHDVDHPGRTNSFLCNAGNQLAVLYNDTAVLESHHVALAFQLTLENDQCNIFKQMERNDYRTLRQSIIDMVLATEMTKHFEHVNKFINSINKPLTAQESEEPDRSLEDIKAMLKTPESRALIKRMMIKCADVSNPCRPLEHCIEWAARISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFVDLPNLMQHLDDNFRYWKGLDEKKLRSLRPPPE
Protein: Serine/threonine-protein kinase PknL (EC 2.7.11.1) (P9WI63)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Phosphorylates the DNA-binding protein Rv2175c. May be involved in the regulation of cell division and cell envelope biosynthesis.
Subcellular location: Cell membrane {ECO:0000305|PubMed:18175374}; Single-pass membrane protein {ECO:0000305|PubMed:18175374}.
Interaction partners:
- DNA-binding protein Rv2175c
- Serine/threonine protein phosphatase PstP
- Glycogen accumulation regulator GarA
- Serine/threonine-protein kinase PknG
- FHA domain-containing protein FhaB
Sequence:
MVEAGTRDPLESALLDSRYLVQAKIASGGTSTVYRGLDVRLDRPVALKVMDSRYAGDEQFLTRFRLEARAVARLNNRALVAVYDQGKDGRHPFLVMELIEGGTLRELLIERGPMPPHAVVAVLRPVLGGLAAAHRAGLVHRDVKPENILISDDGDVKLADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTGHTPFTGDSALSIAYQRLDADVPRASAVIDGVPPQFDELVACATARNPADRYADAIAMGADLEAIAEELALPEFRVPAPRNSAQHRSAALYRSRITQQGQLGAKPVHHPTRQLTRQPGDCSEPASGSEPEHEPITGQFAGIAIEEFIWARQHARRMVLVWVSVVLAITGLVASAAWTIGSNLSGLL
Protein: Glutathione S-transferase (EC 2.5.1.18) (X5D932)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKGLEKISAYMKSSRFLPRPVFSKMAVWGNK
Protein: Cyanate hydratase (Cyanase) (EC 4.2.1.104) (Cyanate hydrolase) (Cyanate lyase) (P00816)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
Interaction partners:
- Carbonic anhydrase 1
- Cyanate transport protein CynX
- Carbonic anhydrase 2
- Carbamate kinase-like protein YahI
- Carbamate kinase-like protein YqeA
- Carbamate kinase
- HTH-type transcriptional regulator CynR
Sequence:
MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
Protein: Bromodomain containing 7/9 (LD22651p) (Q9VLX2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Polybromo
- Brahma associated protein 111kD
- Brahma associated protein 170kD
- Supporter of activation of yellow protein
- Brahma associated protein 155 kDa
- Brahma associated protein 55kD
- Brahma-associated protein of 60 kDa
- ATP-dependent helicase brm
- GH08712p
- D4, isoform A
Sequence:
MGSSKKHKKNKSERREKYEEYSQHQDPAQLQRGLKLILKVGSNATPEYSANSPMVDGGPPTAAEAMMSPVPEELQDHQGHRERHKKSKKKKKKKDREKKHKHHKEKRHRSRDRHRDAGSDEDMMAGADDAACSGFAPSSVAPPAADPDSSQDGFSFMDDDQSQPLPENILFFAGITTDNSPSNCPVTKPIAPRKLDDILMGSSPNSSSLQSSSLGLIGSSPTKPLPDLLIPSPSTPGGANSLNALTPKALEAPKTPSSSSESGREPRSCVLKLKQQKSPLNKLLEHLLRFLEKRDPHQFFAWPVTDDMAPGYSSIISRPMDFSTMRQKIDDHEYTALTEFTDDFKLMCENAIKYNHVDTVYNKAAKRLLQVGMKHLQPENLMRSLKPLSGYMRELTARELGFELSSNDMSRENNDSADEGASTGAEEPRTPAQLEEEERKRTLRLENAPKTHFEPYVDDLTGEEILAQVQNAAQQAKQRVNAKKNAHKMGFLRQMKDGTTTLNLVIKEENEGPERVVTIGDLVGKLQKGSAQLQTRQVDKRNAVRTVKSLNYGAFASFAPTFDSRFSTLSAEETQLVLRTYGDASSAEYAESILQFTKDSNYGTTIANGLLDILTNGEHSKSLDELYNMQLHSYEQREIEKCFEQEEETSSQQETTAQIEQEYEKYKNTHVDFKGLQSLGELGIDVSFLDGMEAEMKSYELNRRMHEHLSQNLTLIEKLRVAQHDRLSQPLPNHLGLVQPAGQEEIQTAQQLTQQISDLAKKLPPSAIADPYALRKAMGMSYAGLPPPRPVSPRVQLPELLQQPVALPQLQPVAMEIDESDEQHGGGDLENELREFLESGSGLHSANPADDNSIVAQLLLN
Protein: Autotransporter adhesin/invasin TibA (Q9XD84)
Organism: Escherichia coli O78:H11 (strain H10407 / ETEC)
Function: Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:10417177, ECO:0000269|PubMed:8039917}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MNKVYNTVWNESTGTWVVTSELTRKGGLRPRQIKRTVLAGLIAGLLMPSMPALAAAYDNQTIGRGETSKSMHLSAGDTAKNTTINSGGKQYVSSGGSATSTTINIGGVQHVSSGGSATSSTINSGGHQHVSSGGSATNTTVNNGGRQTVFSGGSAMGTIINSGGDQYVISGGSATSASVTSGARQFVSSGGIVKATSVNSGGRQYVRDGGSATDTVLNNTGRQFVSSGGSAAKTTINSGGGMYLYGGSATGTSIYNGGRQYVSSGGSATNTTVYSGGRQHVYIDGNVTETTITSGGMLQVEAGGSASKVIQNSGGAVITNTSAAVSGTNDNGSFSIAGGSAVNMLLENGGYLTVFDGHQASDTMVGSDGTLDVRSGGVLYGTTTLTDKGALVGDVVTNEGNLYYLNNSTATFTGTLTGTGTLTQEGGNTRFSGLLSQDGGIFLQSGGAMTMDALQAKANVTTQSGTTLTLDNGTILTGNVAGDSTGAGDMAVKGASVWHLDGDSTVGALTLDNGTVDFRPSTTTRMTPAFQAVSLALGSLSGSGTFQMNTDIASHTGDMLNVAGNASGNFVLDIKNTGLEPVSAGAPLQVVQTGGGDAAFTLKGGKVDAGTWEYGLSKENTNWYLKADTPPPVTPPTNPDADNPDAGNPDAGNPDAGNPDAGNPDAGKPGTGKPDAGTSSSPVRRTTKSVDAVLGMATAPAYVFNSELDNLRFRHGDVMQNTRAPGGVWGRYTGSDNRISGGASSGYTLTQNGFETGADMVFDLSDSSLAVGTFFSYSDNSIKHARGGKSNVDSSGGGLYATWFDNDGYYVDGVLKYNRFNNELRTWMSDGTAVKGDYSQNGFGGSLEAGRTFSLNENAWAQPYVRTTAFRADKKEIRLNNGMKASIGATKSLQAEAGLKLGMTLDVAGKEVKPYLSAAVSHEFSDNNKVRINDTYDFRNDISGTTGKYGLGVNAQLTPNAGVWAEARYENGKQTESPITGGVGFRINF
Protein: Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC) (O96623)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general role in the rapid activation and adaptation of the actin system to its multiple functions.
Subcellular location: Cytoplasm, cytoskeleton. Cell projection. Cytoplasm, cytosol. Cytoplasm, cell cortex. Cell projection, pseudopodium.
Interaction partners:
- Actin-related protein 2/3 complex subunit 5
- Actin-related protein 2/3 complex subunit 1
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2
- Actin-related protein 3
- WASP-related protein
- Wiscott-Aldrich syndrome protein
- SPIN90/Ldb17 leucine-rich domain-containing protein
- Guanine nucleotide-binding protein subunit beta
Sequence:
MLLLETHNRILYDEVISHFEGDRRVNNIFADFDGVKFNVQTSDDKSSLMVSVSLHAAADLLKNGGSALLKSVYGDMLQAKPEGGYDVTLVIQSSFSGNKEELAKKVSLLKRHLVAAPFLMVFEGIEAKKPLPEIIAINYRTDETFYLKPQGDNVIVIFDIAFKDADDVILSKIFLQSFVDVRKTISNVPSITFSQKDPPLELKGVKGVRAGQANHGFVSFVLFPAHIKKPQESADLIQTFRDYLHYHIKCAKGYMHTSMRNRVESLIQVLNRAKPEPVNTVKRTITGKFFKQN
Protein: COBRA-like protein 9 (Q9FJ13)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
- Adenine nucleotide alpha hydrolases-like superfamily protein
- Expansin-A7
- At5g05500
- Endoglucanase 5
- Protein SEED AND ROOT HAIR PROTECTIVE PROTEIN
- Pollen Ole e 1 allergen and extensin family protein
- Type I inositol polyphosphate 5-phosphatase 5
- Leucine-rich repeat extensin-like protein 1
- Kinesin-like protein KIN-UC
- Protein MALE DISCOVERER 2
Sequence:
MGVLLPIFFGVLLLFTVTPPSMSQLPPTIMVPAPAPAPISPSDLCNGIFLSYDFILGRKIPPNDTADQPYRFESVLTVLNNGREELKEWRVFVGFQHNEILISATDALIVNGTELPALVGNGTIFGGYPVSDLKTAIQTAGDLKQMTAEIELVGTQFMVAPPAVPLPSNISLVNEGWLCPVPTLQSKRELTTCCIRDASIIVNTTITTKFLPRQPGDLTIMYDVIRAYDQNYLTEVTMENHNPLGRLDHWELSFDWMRDEFIQKMQGAYPTVVDATKCIFGPQSLIYTGLDFADVLTCERRPIIIDLPPTKKDDSTLGNIPSCCRNGTILPRIMDPSKSVSVFTMQVAKMPPDFNRSALFPPQNWRIKGTLNPDYSCGPPVRVTPTFYPDPSGMPTNKSSFASWQIVCNITQAKTEIPKCCVSFSAFFNDSIIPCNTCACGCVSETRRTCSAETPSLLIPPDALLLPFENRTALTLAWNALKHKTLPNPMPCGDNCGVSINWHMASDYRGGWTVRITIFNWGEIDFPNWFLAVQMKKPALLGFEKAYSFNASLLSVDGGVNNTIFMEGLPGLDYLVAEADEKDPKKKNIRIPGKQQSVIQFSKKLTPGINVAERDGFPAKVIFNGEECLLPDLLPMASGGRRNGAITVLSFITFYVAAFMVLL
Protein: Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1) (Q6PD10)
Organism: Mus musculus (Mouse)
Function: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
- Inositol-pentakisphosphate 2-kinase
- Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
- Inositol hexakisphosphate kinase 2
- Inositol hexakisphosphate kinase 3
Sequence:
MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTPEREQPRRKHSRRSLHRSGSGSDHKEEKASLSFETSESSQEAKSPKVELHSHSDVPFQMLDSNSGLSSEKISYNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRSELRLKHVDMGLPEVPPPCGPSTSPSSTSLEAGPSSPPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ
Protein: Basic leucine zipper 1 (AtbZIP1) (bZIP protein 1) (Q9FGX2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds to the C-box-like motif (5'-TGCTGACGTCA-3') and G-box-like motif (5'-CCACGTGGCC-3'), ABRE elements, of gene promoters involved in sugar signaling. Activated by low energy stress both at transcriptional and post-transcriptional mechanisms. Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark-induced starvation response. Transcription activator of the mannan synthase CSLA9. Recognizes and binds to DNA-specific sequence of CSLA9 promoter.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Basic leucine zipper 63
- Basic leucine zipper 8
- Basic leucine zipper 25
- Basic leucine zipper 9
- Basic leucine zipper 10
- Asparagine synthetase 1
- At5g04840
- Protein NLP7
- Basic leucine zipper 34
- Basic leucine zipper 24
Sequence:
MANAEKTSSGSDIDEKKRKRKLSNRESARRSRLKKQKLMEDTIHEISSLERRIKENSERCRAVKQRLDSVETENAGLRSEKIWLSSYVSDLENMIATTSLTLTQSGGGDCVDDQNANAGIAVGDCRRTPWKLSCGSLQPMASFKT
Protein: Replication factor C subunit 4 (Replication factor C subunit RFC4) (Q6DRF4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MQAFLKGSSSQSVKAQKPSSSSSSGGEKKQRAVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELYGPDLYRQRVLELNASDERGIQVVREKVKRFAQLTVAGTRPDGKTCPPFKIIILDEADSMTSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENLKYTTEGVDALVRVSEGDLRKAITFLQSGARLNSEREITEQTIIEIAGVVPPKVIQSLLHICYKGTFEKLEVAVKDMIDQGYAATNLLNQLHDVIIEEQLSDKQKSVITEKMAEVDKCLADGADEYLQLLSLCSVIMQQATQNT
Protein: LD04853p (Metastasis associated 1-like protein) (Q9U6X3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MATNMYRVGDYVYVETTPNSPYLIRRIEELNKNQTGNVEAKVMCFYRRRDLPNPLVQLADKHQLATAEDSPLATKLKKTWLRTPVSEEQAAQAVLDPSIAALDEERTSPTQTSGGGGSATGNSGSNSSGTSNNNSSSTAIGGGAGGSGGAGGDAEKGEALTSKQRYQIKHRELFLSRQVESIPATQIRGKCSVTLLNETESLQSYLNKDDTFFYCLVFDPNQKTLLADKGEIRVGSRYQCDIPAKLKDTATDDRKLEELESLVWTPEHSLTDRKIDQFLVVSRSIGTFARALDCSSSVKQPSLHMSAAAASRDITLFHAMNILHKHEYSIEESMSSLVPSTGPVLCRDEIEDWSASEANLFEEALEKYGKDFNDIRQDFLPWKTLKQIIEYYYMWKTTDRYVQQKRVKAVEAELKLKQVYIPQYNNNGKGNGTSTKAGGGIYNGTTNGSTDLSSNGKPCESCGTTKSSQWNSVSSGHSTSRLCLSCWEYWRRYGSMKSATKGDAGEGDAKKKSSSAASTPTATLAGLATTPTAVVDLNDDEKISDLTNRQLHRCSIVNCGKEFKLKTHLARHYAQAHGIAISSGSPRPIMKTRTAFYLHTNPMTRVARAICRSIVKPKKAARQSAYAINAMLVKQEFTNRISGKSQAEIKKLLLLKPKDRGSVTKIANRLGAPGSGPHEWLVLTPKDKMPLPAVVSFPKPPKAPDGSLVYDRVPNKSPDVVAVPADKELTIIPTQATSTIRKRAHEDQQLNGTEVTIVPSGPPAKRPNKDPMPSHCPSPEQFAAMMAASGQPLSRHHLNGKQKIAQMARGGNGRKQVISWMDAPDDVYFRANDTHKKKKKK
Protein: Meiotic expression up-regulated protein 14 (O94756)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in nuclear division during meiosis II where it stabilizes the proper segregation of the spindle pole bodies. Also has a role in the formation and extension of the forespore membrane.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:12759375}. Nucleus membrane {ECO:0000269|PubMed:12759375}; Peripheral membrane protein {ECO:0000269|PubMed:12759375}; Cytoplasmic side {ECO:0000269|PubMed:12759375}. Prospore membrane {ECO:0000269|PubMed:12759375}.
Interaction partners:
- Uncharacterized protein C17D1.07c
- Meiotic coiled-coil protein 4
- Probable prephenate dehydrogenase [NADP
- Sporulation-specific protein 3
- Histidinol-phosphate aminotransferase
- Multifunctional tryptophan biosynthesis protein
- Chorismate mutase
- Meiotically up-regulated gene 103 protein
- Chorismate synthase
- Pentafunctional AROM polypeptide
Sequence:
MPKSSNLKMQRKGSLRENGLVKGLNKNKFSISKLKELSHADDSRKSHRIIRSGKSSGEAYKQAGKGLMNLGNHLSDWGAKSSNLSLNDISDKIGVLVSELGETEIEFVKAFNENRIKFKAIRAMEDSIAPSRAHRQRLISSIEREEERDPLSPKLTDLQNQLVRTEAENLVGEMQLDNTSREVFKSSFQGLMDAFQLRAQKQMTLSYYASQLAELINDEVAYPGDNPAAYSQKYATQIMHQCVESMARLLAPVTSETTEHVGSDCEFTRKSSSSVEFSDHSQDSGDPSQQNILQVKNVQAVLSIPEAESYKAQLLSSIAEEQKKKELQAKSTVFL
Protein: Fin bud initiation factor homolog (Q9CQS3)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000250}. Golgi apparatus {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Interaction partners:
Sequence:
MVFPKLIWMGFFCHLCRGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDRRRCSQGEGGQASSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLDISVGLRDKYELLAHTIRSHGTRLGRLKSDYLEGGAQKTG
Protein: C-C chemokine receptor type 9a (Chemokine (C-C motif) receptor 9a) (B0V1K7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Early endosome {ECO:0000256|ARBA:ARBA00004412}.
Interaction partners:
- C-C motif chemokine 21
- C-C motif chemokine 25
- Chemokine
- Chemokine
- Stromal cell-derived factor 1
- CD4-1 molecule
- C-C motif chemokine 19a.2 precursor
- Chemokine
- C-X-C chemokine receptor type 3
Sequence:
MMNVTELITSLTPQTSEYEEYGDFSTTSDYGDTDDGFCPKSKVREFRMYYEPMLYWMIVILGAIGNTLVVWIYTHFKNRLKAMTDVYLLNLALADLFFLCTLPFWAADSIYGWAFGSGLCKVVSAVYKINFFSSMFLLTCISVDRYIVIVQTTKAQNSKRSRLLYSKLICVLVWLLAALMSIPECLFARSKEDDESNTFCTMVYWNNENNRTKILVLALQICMGFCIPLVVMIFCYTNIIRTLLKTRNFQKHKALRVILAVVAVFVLSQLPYNGMLVFEATQAANMTVTNCTESIRFDIAGQVMKSIAYMHSCLNPFLYAFVGVRFRKDVIRIFQNIGCVSNLKNSKLAGIPHRSSVMSDTDTTNALSL
Protein: Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7) (Q16629)
Organism: Homo sapiens (Human)
Function: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
Subcellular location: Nucleus {ECO:0000269|PubMed:11336712}. Cytoplasm {ECO:0000269|PubMed:11336712}.
Interaction partners:
- Serine/arginine-rich splicing factor 3
- Serine/arginine-rich splicing factor 1
- Transformer-2 protein homolog beta
- Serine/arginine-rich splicing factor 9
- Splicing factor U2AF 65 kDa subunit
- Serine/arginine-rich splicing factor 6
- SRSF protein kinase 1
- Heterogeneous nuclear ribonucleoprotein A1
- Serine/arginine-rich splicing factor 11
- Nuclear RNA export factor 1
Sequence:
MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERMD
Protein: Germacrene A synthase (LsGEAS) (EC 4.2.3.-) (Beta-elemene synthase) (EC 4.2.3.-) (T1RRS0)
Organism: Lavandula stoechas (Butterfly lavender)
Function: Sesquiterpene synthase involved in the biosynthesis of volatile compounds widely used in aromatherapy and folk medicine, and present in culinary herbs. Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into germacrene A and beta-elemene. Not able to use (2E)-geranyl diphosphate (GPP) as substrate.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MAQQEAEILRPLANFSPSLWGDQFIKNDSDAKVRYIFHYVDYTNLSMLTATGTKMVDTMNLIDTLERLGVSYHFEHEIEEILQQFFNLNTDYNDEAYDLYTVATHFRLFRQHGHRITCDIFGRWRDENGKFHEGLKDDAKGLLSLYEASYLRTRGETILDEALDFTTASLKSIAPNLESPLRRQVEHALVQQLHWGNPRIEARNFISLYEEYEDKDESLLRFAKLDYNLLQMMHKEELHEVSRWWKELDLVAKLPYARDRVVECFFWAMGVYHEPQYSRARVMLTKTIAMTSIIDDTYDAYGTIEELDIFTEAIERWNVEEMKRLPEYIKPFYKALLELYEQFEEELAKEGRSYATHYAIESLKELVRSYHVEAKWFIQGYLPPFEEYLKNALITCTYCYHTTTSLLGVESAVREDFEWLSKKPKMLVAGLLICRVIDDIATYEVEKDRGQIATGIESYMRDNGATKEEAITKFFEIANDAWKDINEECMRPSPHSRDVLMRILNLERIIDVTYKGNEDGYTQPEKVLKPHIIALFVDPIQI
Protein: Cyclin-A3-3 (G2/mitotic-specific cyclin-A3-3) (CycA3;3) (A0MEB5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cyclin-dependent kinase B1-2
- Cyclin-dependent kinase B1-1
- Cyclin-dependent kinase B2-2
- Cyclin-dependent kinase B2-1
- Cyclin-dependent kinase A-1
- Cyclin-dependent kinases regulatory subunit 1
- Cell division control protein 6 homolog
- Wee1-like protein kinase
- Cyclin-dependent kinases regulatory subunit 2
- Transcription factor E2FC
Sequence:
MVSKKDKQIHSDHNPQDASPVEWAEIRHKLLAFQENIQSGSDIDARSDDPQMCGLYVSDIYEYLRELEVKPKLRPLHDYIEKIQEDITPSKRGVLVDWLVEVAEEFELVSETLYLTVSYIDRFLSLKMVNEHWLQLVGVSAMFIASKYEEKRRPKVEDFCYITANTYTKQDVLKMEEDILLALEFELGRPTTNTFLRRFIRVAQEDFKVPNLQLEPLCCYLSELSMLDYSCVKFVPSLLAASAVFLARFIILPNQHPWSQMLEECTKYKAADLQVCVEIMLDLYLSRSEGASKAVREKYKQHKFQYVAAIPVYQELPVTFWEDVVTI