wanglab/gogpt-training-data huggingface dataset:
Protein: Prolyl Carboxy Peptidase like (Q9GRV9)
Organism: Caenorhabditis elegans
Interaction partners:
- G-protein coupled receptors family 1 profile domain-containing protein
- F-box domain-containing protein
- F-box domain-containing protein
- Sushi domain-containing protein
- LITAF domain-containing protein
- Domain of unknown function WSN domain-containing protein
- Serpentine Receptor, class T
- C-type lectin domain-containing protein
Sequence:
MLQPLLLAYLTMSAFSIIPTHFPFKEHLTKQPASPATSVTTGYLSQKLDHFSNDSQVFFTQQYFYTERLSVSNQKVAFLYVNTEGNEEIAVMTDERSPVVKAAKRFGAQLFALKHRYYGASKPNFQNFDASALRYLTSRQAIQDILSFIKYANTQFNMNPDVRWVLWGTGYGGILAAEARKTDPVAVSGAISSSAPLRRLYDFWQFNDFVGNTLMQIGGSNCYGRVQQGFADIRQAMKTTAGRSQISDLFQLNPRLDQTQLGYNDIQMFYTAIIGPFQEIVQFNNDFNISITDMCTIIANSSWTNMEVVRQAYVYLSTTLTGSVQPMTIASYQKVVNDLKNDSVSSPFVENRMWTYQICTELGWFPTTNNNEQGLFGAVVPTSIYINQCSDIFPDASLTATSIRDSIVSSDSVYTGTNVVFTNGFYDPWSVLGQETSRDFSVVAYVIPGASYLSDFFPGDSDNQYIQKAHDLMIENINIWVNGPKSTRILGDPTVPWTPPQLGGSEASELQSSKVFSRTLPRTPSRGIFHRRHLELLASSYPAGFEQGTFRQRQDHFDNLNVDFFQQKFYKNSQWARPGGPNFLMIGGQEAEGESWVLNEKLPWLISAQKYGATVYLLEHRFYGDSLVGNNTNLNLLSSLQVLYDSAEFIKAINYKTQSSTPWITFGRSFPLSAWTRAIFPDLVTGAVSSSGAILAKTDFFEYLMVMETSIRKYDNSCADRIKSGFDEIRGLFLTSEGRQDLSKIFQLLPGFSENVTETDQHFFFSNLYSNFQLAVQFSGDNSGPWADGYGIPEMCRFMTGAGTPLDNIVAFNAYMTSFNNGGGTYTGMGNNYTAMIYNLKNSKDYGEGVDPTLLWTWQTCTEYGGFQSADSGSGLFGSPVPVSFLIQMCMDLFGNTYDRSKIDSLIDFTNYKYGGRDNFKGSNVVFINGNIDPYHVLGLFNSPDSSVVSYLIDGSSHCADMFPARDSDVPGLKVARDLVDQNIGVWLGGQVNITTTTATTTSNSTSYPSTLYSLEPTTTKSTSVNRVFISFCVIMFDFLVL
Protein: SD08060p (Q8T9B8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSAGVQERLQLSRMPLDTWSKREQLILASAVSCSGDQNWITVSRTLKTICGNGSSNRPADWFSQKNCAMQYGNLLESVEATKRKKRSSESSAGVSSPATVETPTELLLRRLTEERQAEIKAQMRQDQETYRRIQREIESLQSDAVTEQELQDMWLEIEKEQEARRIEEMKLENRMREREQRKKDLASNWRNSSLAVKRSNQAADTTSVDMDVEDINTSGNGKHQTGPSPLLTSLLKSPTGNAPATPTPGGAAPAAGGTGSVARATAPTITSLLTSGPSSAVANQPVITMKSPTDAAFMSRPITGPPASEALASTTPTLERSPSQAAPTLSMLLEKNKAAAKVNEGGSLVKPEGSGNQEQGVDEDTSSAAGTADSDEADPNEAQLLEVFKNIDQIIDDIDIDMASVIDDEILKNVDDVVASPSNDKAEVIDFEDKLDALKREQSKSSPASDKPKSVELVIGSSDDSNDNIPLAAVASQESKDRGQSGGESTRGTEDAESEPLTSEVAVEEIGETITIISTSSEDTAGSPPTKMEEDGATDSLSKKEDATEDKSEQESSAQGQNKAGGSTDEPELIDHQATREAQSKSGKDTAGKPVTMQEKTTTQSAPVPVDLHDTDEESSSLTDSSKHDDHPRSAKAKPPALKLALDDSKSELELSGTPQPPSAPARTPLLRKLPHRDRSESPMVDDDATTASDHSTARSTRRRCSSTPVIDSIPNSPASSEHTDDRRETRAASKKLFLSIYAMLLDSKHAAPFKRPFHDEHAQRHADLCLRPMDFPTIKRNIDSGFIRSLSELHRDVLLMAHNVLVAYKPHTTQHKTARLFVQDCQAIKEFSQLPDVQAGITATPVSNTGSLRADKSSGSKARSGSRKSQRHH
Protein: All-trans-zeta-carotene desaturase (EC 1.3.99.26) (Phytoene dehydrogenase) (Phytoene desaturase) (Q02861)
Organism: Myxococcus xanthus
Function: Dehydrogenates carotenes in the trans conformation: converts all-trans-zeta-carotene into all-trans-lycopene, one of the last dehydrogenation steps of lycopene biosynthesis.
Interaction partners:
Sequence:
MASEGGSVRHVIVVGAGPGGLSAAINLAGQGFRVTVVEKDAVPGGRMKGLTLGASGEYAVDTGPSILQLPGVLEQIFRRAARRLEDYVKLLPLDVNTRVHFWDGTHLDTTRHLDRMEAELAKFGPRQASALRQWMEDGREKYGIAYQKFICTSADNLGYYAPWRLAPTLRFKPWQTLYRQLDGFFHDDRVTYALAYPSKYLGLHPTTCSSVFSVIPFLELAFGVWHVEGGFRELSRGMMRCARDLGATFRMGTPVEKVRVDAGRAVGVKLVGGEVLDADAVVVNADLAYAARSLIPAEAREGSRLTDAALERAKYSCSTFMAYYGLDTVYADLPHHLIYLSESARRTDRDALEDRHVDLEDPPFYVCNPGVTDPSGAPAGHSTLYVLVPTPNTGRPVDWVKTEQALRERIPAMLEKVGLKGVREHIREERYFTAETWRDDFNVFRGAVFNLSHTWLQLGPLRPKVKNRDIEGLYFVGGGTHPGSGLLTIMESANIAADYLTREAGKGPLPGWPYVPPLEPESPVQARAG
Protein: Acyltrehalose exporter MmpL10 (P9WJU1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Required for the biosynthesis of polyacyltrehalose (PAT) and the transport of diacyltrehalose (DAT) and possibly PAT to the cell surface.
Subcellular location: Cell inner membrane {ECO:0000305|PubMed:25124040}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Acyltransferase PapA3-trehalose mycolipenoyltransferase)
- Mycolipanoate synthase
- Diacyltrehalose acyltransferase Chp2
- 2'-acyl-2-O-sulfo-trehalose
- Sulfolipid-1 exporter MmpL8
- Trehalose-2-sulfate acyltransferase PapA2
- Conserved hypothetical Mce associated protein
- Putative fatty-acid--CoA ligase FadD21
Sequence:
MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHESGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRGWVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVSQIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLNRLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKTFNEIDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPMCGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSLNSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQTKNMGIGLNQASAFLMAMGNDASQPSMAGFNVPPQVLKSEEFKKVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMSGYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVVISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLRDESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATLLGRASWWPGHPWQRCAPEEGQMSARMSARTKTVFQAVADGSKR
Protein: Endolysin (Q7Y4H8)
Organism: Streptomyces phage mu1/6
Interaction partners:
Sequence:
MPDLWMPGAEVHDLGDHAPTDQQYPPKAIAHITWDRNATAAAPQDWATFDDLVGYFTGSGAGSAPHLIWDPFSGRVAQLFPADSRSKSVVDSPGGTRTNRAGRVVIQIEAVFFPYCRYQGQVYPRLVDTPCAGWDRIHAWISSWGVPDVWPMGRPVDFTSHRSEQVWESQGGWYAHAHVPENDHQDPGSWPDFGQSGANPQPSPPPAQDPTPARYQTTINGLAYGYGAQGDQVTAVGRALVAHGFGSHYQQGPGPNWTDADTENYADYQRSLGYTGQAADGVPGSDSLRQLLGTLPGGRTVSLAHVIAAAQADPPAAQGHQTYGPDVQIVEQALADEGLLDQQWVDGSFGSRTVSAYAAWQRRCGYSGSGADGIPGKASLDRLAAAHGFTTTD
Protein: Thiohydroximate-O-sulfate sulfur/sulfate-lyase (nitrile-forming) NSP5 (EC 4.8.1.5) (Nitrile-specifier protein 1) (AtNSP1) (Nitrile-specifier protein 5) (AtNSP5) (Q93XW5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes simple nitriles, but not epithionitrile or thiocyanate formation. Converts allylglucosinolate and benzylglucosinolate to their corresponding simple nitriles in the presence of myrosinase.
Interaction partners:
- UPF0235 protein At5g63440
- Endonuclease or glycosyl hydrolase
- Cysteine proteinase RD21A
- At1g09850
- Probable cysteine protease RD21C
- Probable cysteine protease RD21B
- Myrosinase 2
- Cytosolic sulfotransferase 11
- Arginine/serine-rich-like splicing factor
- Myrosinase-binding protein 1
Sequence:
MCPVENKWLKVGQKGAGPGARSSHAMTVVGNKVYCFGGELKPTIHIDNDLYVFDLETQEWSIAPATGEAPFPCFGVSMVTIGSTIYVYGGRDDKRRYNGLHSYDTETNEWKLLAPVEEGLPGRSYHSMAGDDRKVYVFGGVTAKGRVNTLHAYDVVDQKWVEYPAAGEACKGRGAPGLVVVEGRIWVLFGFDGNELGDIHCFDLASEQWKAVETTGDVPAARSVFPAVSYGKYIVIYGGEEEPHELMHMGAGKMSGEVYQLDTETLVWERIVCGNEEEKPSQRGWCAFTKAVKDGEEGLLVHGGNSPTNERLDDLVFWGFSHLNVN
Protein: Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1) (Q9UPN7)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16769727, ECO:0000269|PubMed:18186651}.
Interaction partners:
- Serine/threonine-protein phosphatase 6 catalytic subunit
- Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
- Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
- Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
- Splicing factor 3B subunit 1
- Serine/threonine-protein phosphatase 6 regulatory subunit 3
- NF-kappa-B inhibitor epsilon
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Diacylglycerol kinase zeta
- Serine/threonine-protein phosphatase 4 catalytic subunit
Sequence:
MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAWVTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLLASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQDVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLATLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLELLAQGALESTVSSVGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVVKLLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPPDSSPETPIQNPVVKHLLQQCRLVERILTSWEENDRVQCAGGPRKGYMGHLTRVAGALVQNTEKGPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRLKEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPGSQ
Protein: Matrix metallopeptidase 28 (Epilysin) (Matrix metalloproteinase-28 variant B) (Q8BG29)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MVAGVSLLLRALPLLLWGCQDAQPTQHGLPELRQEAEAFLEKYGYLSEQGSKAPASAQFRNAIREFQWISQLPLSGVLDQATLRQMTRPRCGVADTDSHATWTERISTLLAGHRAKMRRKKRFAKPGNKWYKQHLSYRLVNWPERLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLANAFDGPGGALAHAFLPRRGEAHFDGDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKKLGRDALLSWDDVLAVQSLYGKPLGRSVATQLPGKVFTDFEAWDPHNSQSRRPETRGPKYCHSSFDAITVEPRPLQKRWPGLPPGIEAAAVSLEDGDFYFFKGNRCWRFQGTKSVWGFAQLCRAGGLPRHPDAALFFPPLRRLVLFKGSRYYVLAQGGMQVEPYYPRSLRDWAGVPEEVSGALPRPDGSIIFFRDDHYWHLDQAKLRVTSSGRWATELSWMGCWNANSGGALF
Protein: Serine/threonine-protein kinase RIM11/MSD1 (EC 2.7.11.1) (Regulator of IME2 protein 11) (P38615)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Serine/threonine protein kinase that is thought to function in regulating kinetochore activity and entry into meiosis. Could phosphorylate IME1.
Interaction partners:
- Meiosis-inducing protein 1
- Transcriptional regulatory protein UME6
- Nucleosome assembly protein
- Casein kinase I homolog 2
- Serine/threonine-protein kinase GIN4
- Casein kinase I homolog 1
- Protein kinase MCK1
Sequence:
MNIQSNNSPNLSNNIVSKQVYYAHPPPTIDPNDPVQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLDDGKINQITTDLKLLEFDENVELGHLSPDELSSVKKKLYPKSK
Protein: Large ribosomal subunit protein uL30m (54S ribosomal protein L33, mitochondrial) (YmL33) (P20084)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL22m
- Large ribosomal subunit protein mL41
- Large ribosomal subunit protein bL34m
- Large ribosomal subunit protein mL49
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein uL23m
Sequence:
MVFYKVTLSRSLIGVPHTTKSIVKSLGLGKRGSIVYKKVNPAIAGSLAKVKELVKVEVTEHELTPSQQRELRKSNPGFIVEKRTID
Protein: Fibroblast growth factor (FGF) (Q8AY90)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 1-A
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor.
- Sonic hedgehog protein
- Bone morphogenetic protein 4.
- Platelet-derived growth factor receptor alpha
- Vascular endothelial growth factor receptor kdr-like
- Vascular endothelial growth factor receptor 2
Sequence:
MCKWKVTKGASAWFRLSCLSLPLLLLFLCSALPVACHDTHRAIRAPRGTNSSSSAVVGRHVRSYNHLTGDVRRRKLFSYQKFFLRIDKNGKVNGTKSKDDPYSTLEIKSVDVGIVAIKGIQSNYYLAINKKGVVYGARDFGIDCKLIERIEENRYNTYASAEWMNKKKHMFVGLSANGRPMRAKKTRRKNTATHFLPIPIV
Protein: Mitochondrial translation factor ATP22 (P50273)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Translation factor specific for subunit 6 of the mitochondrial ATPase. Required for assembly of the CF(0) component of the ATPase.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:12646576}; Peripheral membrane protein {ECO:0000269|PubMed:12646576}; Matrix side {ECO:0000269|PubMed:12646576}.
Interaction partners:
- MIOREX complex component 5
- ATP synthase subunit a
- ATPase expression protein 3
- Protein PET111
- Mitochondrial COX1 translation regulator PET309
- Nuclear control of ATPase protein 2
- ATP synthase protein 8
- Mitochondrial ATPase complex subunit ATP10
- Mitochondrial inner membrane protease ATP23
- RNA-binding protein RMD9, mitochondrial
Sequence:
MLKCICRVYSQPLAQMVTSPLFKHMGSAGTYTILPITNLRHLSTKNCPLKIKSNRSEPLQFGDFERQVPCSRKSGSSKNVQKRLYELRQLKTVLSETFGVTEYASFFESLRNALHINNCSENEKKKLLYDIILHQHELYPEVARKIGFYLPGEVHRWFWYHIPKSESFNHYLFLLKSDVLLFTSNYCTRFTNRLIKGTEMERQLATFQIFLHDETNIKFIMEKVLKLHTFDSLIALVNGLVKAKNFRFIKVFIQALLQKLEQHCYSGKDGAKQKNLRYVKFNNTLLYYLLKSGNVELFIKTFQEELKFIVSSGLLNHIDGNEHILNFPIHHYLNLLRISNRQEELFNVISCLQSSPLMKYKLFKEFLMGELIASFQAFRDPKLVCKYLLSSYSSKASANILNALGIWGWLYHSKSTTLTAPTLARELKNKNNILPNTMRIGSPVTVPILTELYRSLLSSSSVSLESGQFKNCLLDLYYKYKSFLSEEAHKYRYWRNDTGILNVFLNYIRFQAREPRLAYNVLLDFYSQPFAKKVVLTTTLCPFSIVAYKNHTLTQAELSELLQVMHKNGVPLTFKFCSAMVMHYVKMRDEKGARSWYNKILFGGFEIRHMALIQIIKDQGWPFPKNFDETLLTELVENNNIKEPTDSTLFTDEDMFEEDGKPRFNDDDVNKCTNIIRETLKSLN
Protein: Plexus, isoform A (Q9W244)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Pineapple eye protein
Sequence:
MEKAKAYIKNELRGGSQQSEPATTPNPTSPASAPGTPQATRHSYPPVELMPSPGAAAHRSARTPGEQYHFGYQAHPAQHYHSGAKSTGRASAPPDNHHVPMTICFVCGGHGSFEPQPLRIRHNAERPSESYFPFLERHEPPNGVPGVVPGQEYVWACMLCFRSLNEQWDAYERQKKPLLQRIYHMKRVDGKGYIGADVATQSEYAAQVLGLSAEHLTQNGLVEGHGDPYALARHYSPQQPSHHHHSTSRNASPSPNPIAAVGGGGEFYPRNSTPSSNHNRYLSRPQSRDMPVASPTSRPPSEPPAMKSAGYAQQKFKLSPAPPVGYQGQAPYHPAQYQQLQQQTAAYHLLQQQVNAGGGATESAHYKGNPYGALPSPGSGPLGPRAASTLEDDNATVLDLRNSSNSSAPPAPRHVGSTASSVSQPSQPQSEVGILDLSMPDKNSITEVCYVCGDEQRRGSLIELSTVKPRETGRPGPSVPYFPLFNEQHPRPARSRPKDPRGMIQACLPCYEDLMQQWNVHQASHKPESERSYLLRKRSTPAAERTTFVCYTCGTDTPSSQLRLVYCCPNAEREPYYPFIKTMKVYKNASPISPQGMVQVCSTCNEKHSGLAEGGPPPASSSIHSAVGGGSPSAGHSLESNSAMYSTSGAITGNSGAQFGGRNSPSEKSLANSDSMSNVRFRPYETNSNNSNSNTARDLKQIRRSDSRPNSPSSSQGAIENGHGQYPCSICKVLCPSNKMDWLSTSAEHMNSHAMHFPCLKANAVTNNNNNNNNTNNNNNNNNNELNSNRVLACKDCKDYLASQWETMDAERVPLEHRRYNIPSPMLTSSSPNGSRHGAMSINTPPSTPSISSSTPASTSIYCYLCGLHSDLTLARVLYASKEGSRPYFPLLLKHNSLPNAEQLRNNSALVCTFCYHSMLNQWRKYEAQSPSVNPADRKYNWHDYNCHLCGITTYRKRVRALPVNEFPFVKHQKSDDGLLLENGEYAVVCLDCYESLRQQASQHDRFGVPISRRAYNWVPQPPPPEDSPESAVARLPCGERSDRIHINNALRPVPGKKTTSPKQYDKSKEVPPKAGQKRPATSPAPHIPVPHHLQTPPGGGAGGLPGSSVANSPIPSSAGGNALMNHALPNNHIGTPSPQQQHQHQQHQQQQQQQQHQAQQQAQQQAVAAAVQQQLAAGVGLPPGAIGAASASSRGSFAAALRTLAKQADIKEEDVGGDRSVPTSGAGGPPPSSSGPGSLNSVAGRVGSERPGEDRVSSNKKRSPPSPQPPEKIARLSHTPQTASLQPELLARSGFQPYRSDERLMHPAGAFPLEAYSHFAGLQGIPPAFLNPAGLPYTEQLYLEHRYQLFRAAGAHPSHPHAAALYPQMASPYSHLYSMMPGAALGISPAMHDRMKLEEEHRARLAREEEREREIQREKERELREQREKEQREKEQREKEQREREQREKEQREKEARERKLRDEERERERERQQLLTASHHYSNQLYSPLNRNLLGSMIPHLNMSLRGPPGALHGLPGMSHYHAAAANAQRQSPHGAMGLNLGMAGLPGVPPLGGHGPNLQHHLQQAAMGLAHPGAAGLTHPGFSAAALGLGAHPHSLNLSHPHMSPHHPASLAHQLPPHTSSAGGGGLSNSIPVTASSSLSASSPHTSLNLTSSVKLSADQVPTSTPSGGVSGSGMPPTTSSSHIPNMGHYYHHGHLAAMHAAAAAASGMTPTAAHQQQPLSLPSSPKITPPITPSSSANGGRAGGSPHAMRHHIAAAVAAAAQQSAMIDKAATPVTHEPTTLDLTGSNSNSSNQAPSNASSGQPTNHEVNGAESNGASQTESKEHLAIKEDGHKSSPPPVALEKKPATPNAAADKPIHPDSSPENSSRRSASPQSDANNSLPAVSVTAAASGKCKEETPKILDSDTTATTKTDIEEEKQRARLSVSPTPTAPKIMVASPDTVSTSGGVTSTTSGTTPPPVVSSSTSSAGKAPALTSDEVSTSAATSAAEPTR
Protein: Gastrokine-3 (Q9D0T7)
Organism: Mus musculus (Mouse)
Function: Inhibits gastric epithelial cell proliferation.
Subcellular location: Secreted {ECO:0000269|PubMed:20138039}.
Interaction partners:
Sequence:
MPLHSLERDNMRRLIAPSILVTVFLVPALALTNTSDSYPLDGSVGTQTIHVDALRGVVSIRDNSVQSEWDGVMDYKNDLLAAKLFSKMACVLAKMDPAAFPSLDDITQALGKQASGHYPPTRGLTYTVLPSRIKNLAQYGVPIKDLCRAVPTYFARQQKEGTALTMDPDSCSELQLLSFMGLSICGEIPGL
Protein: RNA-binding protein 4 (Lark homolog) (hLark) (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Q9BWF3)
Organism: Homo sapiens (Human)
Function: RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro.
Subcellular location: Nucleus. Nucleus, nucleolus. Nucleus speckle. Cytoplasm. Cytoplasmic granule. Note=Undergoes continuous nucleocytoplasmic shuttling. Upon nuclear import colocalizes with SR proteins in nuclear speckles. Arsenite stress-induced phosphorylation increases its subcellular relocalization from the nucleus to the cytoplasm and to cytoplasmic stress granules (SG) via a p38 MAPK signaling pathway. Primarily localized in nucleus and nucleoli under cell growth conditions and accumulated in the cytoplasm and cytoplasm perinuclear granules upon muscle cell differentiation.
Interaction partners:
- Eukaryotic translation initiation factor 4E type 2
- Endothelial PAS domain-containing protein 1
- Protein argonaute-2
- RNA-binding protein 10
- Serine/arginine-rich splicing factor 3
- Splicing factor U2AF 65 kDa subunit
- Eukaryotic translation initiation factor 4E
- YTH domain-containing family protein 2
- Heterogeneous nuclear ribonucleoprotein K
- Period circadian protein homolog 1
Sequence:
MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRSGRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAASVYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAASTSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRARYSAF
Protein: Aquaporin 8b (A0A060Y2R1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Aquaporin-4
- Aquaporin-4
- Aquaporin-4
- Aquaporin 1a
- Aquaporin 1a
- Aquaporin
- Uncharacterized protein
- Katanin p60 ATPase-containing subunit A1 MIT domain-containing protein
- AAA ATPase AAA+ lid domain-containing protein
- Katanin p60 ATPase-containing subunit A1
Sequence:
MTEGTMELGDMGTSLMASDSKKAPVQPPNKFERLVQPCLAELVGTMFFVFIGCVSVIENVEAAGRLQPALVHGLAVAVMVACMAEISGSHFNPPFTIAIYLCGGMKLNMVGPYLISQLIGGVLGASMSKLMTTTENYSKAQGAAFALLQSQDQLWGALFGEIAMTCLVTMVVLLGAVNAKSSSPMVPFMVGCTVIINILAG
Protein: F-box and leucine-rich repeat protein 6, isoform A (F-box and leucine-rich repeat protein 6, isoform B) (F-box and leucine-rich repeat protein 6, isoform C) (RE55062p) (Q494G8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSESLSSQVEETKVSDDDGVKEKAEVSTAKDSAETAMEVEADDTGGQQPEQSELLDKEKSATVDINTLTPSTPSQTPPQLLAVETATSGSTAVIPENILSPPKSETQTDETNTATSTSCSPASDGQRSPAADQQSSAPPPQVQAQATPAPVNGSVPKSGKPLSTALSGKKTSKAATTSPRASRCRKTKALPMYESEISDNKMGIRLCIKKSDAGEGAPAGVTSPPVAVPAATKTVRKRVRKPKQQDSDEAEYEPRKKKGGGGGSGGEKKVSTSPDAAEAAGDPVEQSVWAQKLPEEVLFRIFEHAVDTQGCLPTLFRLGRVCSLWRQVSLRPTLWRTMDLTTWVKEKYRTELKLKWFVDNRCSACTDLNVSNWKISDINCFLAKLSSGCPNLAGITLSGWKGFTSDHLTYLVDNMHKLQRLDLSSINVEMNASKSAVGVNSLCNALQTMGSRLTHLYLAHNRLAGIPQIVGILSTHCPNLTLLDLSNVTTQATSHGVLHIEKLQRGCQKLKVLRVTNSHITPSTASMQEIMDSPGFPELEELSVAALTDESRIISDDHLQRILKSSSKLKLLDVRNCTRLTHESLIRLPAWDIKHLFLSGCSVTRDMGSGLELIASKWAHSLIELDLAWANMQQPIDNALRALAEKGRDSPLAHLNLCGSSVSDEAVKEILTNCQNMSSINLASCRGLPRGVKRLMQGPQELGELREVLGVQLKSSSGSN
Protein: Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH subunit beta) (J3KNE3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
AAAGAGAGGGTRRSGTDGTERATDAPPADASAAWGPHGPSTSVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Q1LYN0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004434}.
Interaction partners:
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial
- NADH dehydrogenase 1 subunit C2
- NADH dehydrogenase 1 alpha subcomplex subunit 7
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase iron-sulfur protein 5
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- Uncharacterized protein.
- NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 4
Sequence:
MLSRLSRIYPALSRVRLSSALGSRFVSQTPQSSASGASVPADLRPFAPPLQDSHGHAEVSPFDKNPDFHGFHHDEPIVDEWNMKLAFFFSISLVIVVGSTFIHYLPDHGMRQWARREAERLIVQREAAGLPVLTENYYDPSTIVLPSSEE