wanglab/gogpt-training-data huggingface dataset:
Protein: TBC1 domain family member 14 (Q9P2M4)
Organism: Homo sapiens (Human)
Function: Plays a role in the regulation of starvation-induced autophagosome formation. Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy.
Subcellular location: Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:22613832, ECO:0000269|PubMed:26711178}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:22613832}. Note=After amino acid starvation, Golgi apparatus-associated protein levels increase compared with fed conditions. May be cycling between the Golgi apparatus and an endosomal pool, redistributing to the Golgi apparatus upon starvation.
Interaction partners:
- Trafficking protein particle complex subunit 8
- Ras-related protein Rab-11A
- Serine/threonine-protein kinase ULK1
- Trafficking protein particle complex subunit 12
- Trafficking protein particle complex subunit 13
- Trafficking protein particle complex subunit 2-like protein
- Trafficking protein particle complex subunit 11
- Trafficking protein particle complex subunit 3
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit 6B
Sequence:
MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHSLQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTEREQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDLVVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFARNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH
Protein: NTF2-related export protein (E9QCN6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369002}. Nucleus {ECO:0000256|RuleBase:RU369002}.
Interaction partners:
- Zgc:153681.
- Nuclear RNA export factor 1
- mRNA export factor
- THO complex subunit 5 homolog
- Nuclear transport factor 2
- APC regulator of WNT-signaling pathway
- Nuclear transport factor 2
Sequence:
MSLTVDFRTQVDQSCRYSEEFINIYYECMDKKRRNLKRLYLDKATLVWNGNAVTGQEALGEFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVAAGSVKFEGNKQRFFNQNFLLTAQASPNSDQPVWKIASDCFRFQDWAN
Protein: Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (EC 3.1.3.-) (EC 3.6.1.1) (Q0VD18)
Organism: Bos taurus (Bovine)
Function: Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- inorganic diphosphatase
- Inorganic pyrophosphatase
- Sodium/potassium-transporting ATPase subunit alpha
- Sodium/potassium-transporting ATPase subunit alpha
- Sodium/potassium-transporting ATPase subunit beta
- V-type proton ATPase subunit a
- NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial
- V-type proton ATPase 116 kDa subunit a 2
- ATP synthase F
- ATP synthase peripheral stalk subunit b, mitochondrial
Sequence:
MAAWGERLAGVRGVLLDISGVLYDGGEGGGAAIAGSVEAVARLKRSRLKVRFCTNESQKSRADLVGLLRRLGFDVSEGEVTAPAPAACLILKQRGLRPHLLVHDGVRSEFDQIDTSNPNCVVIADAGEGFSYQNMNKAFQVLMELENPVLFSLGKGRYYKETSGLMLDVGPYMKALEYACGIEAEVVGKPSPEFFKSALQEMGVEAHEAIMIGDDIVGDVGGAQRYGMRALQVRTGKFRPSDEHHPEVKADGYVDNLAEAVDLLLQHADK
Protein: Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2) (Q12908)
Organism: Homo sapiens (Human)
Function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Gastrotropin
- Bile acid receptor
- Organic solute transporter subunit alpha
- Cytochrome P450 7A1
- Phosphatidylcholine translocator ABCB4
- V-type proton ATPase 16 kDa proteolipid subunit c
- Organic solute transporter subunit beta
- Nuclear receptor subfamily 0 group B member 2
- Solute carrier organic anion transporter family member 1A2
- Bile salt export pump
Sequence:
MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
Protein: Elongation of very long chain fatty acids protein 2 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL2) (ELOVL fatty acid elongase 2) (ELOVL FA elongase 2) (Very long chain 3-ketoacyl-CoA synthase 2) (Very long chain 3-oxoacyl-CoA synthase 2) (A0A068C9W5)
Organism: Anas platyrhynchos (Mallard) (Anas boschas)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|HAMAP-Rule:MF_03202}; Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_03202}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MEHLKAFDQEINEFVDYMFGPRDSRVRGWLLLDSYLPTFFLTCAYLLCIWLGNKFMKNRPPFSLRAHLIVYNLGITLLSMYMLIELILATWEGGYNLQCQNLHSAGVADIRVAKVLWWYYFSKVIEFMDTTFFVLRKKSSQITFLHVYHHATMFNIWWCVLNWIPCGQSFFGPTLNSFIHVLMYSYYGLSVIPSMRKYLWWKKYLTQAQLIQFLLTIVHTLSAAVKPCGFPFGCLMFQSSYMATLVILFVNFYIKTYRKAPSRTAVKETPVTTEVKNGFHKDYFTAANGFLNKKAQ
Protein: Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein (T25N20.3) (Q9ZW00)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Histone acetyltransferase subunit NuA4-domain protein
Sequence:
MEGGGGSGERSRIASNTPRSLKEKSDGVGRTVSSTETRQNYQKRSRMVVSDSESSDEFMKPPPRRSGVDRKTLGAKEKFVRKRDRVEHDRNGYVRRNNEASGSFMKMNKLDIFEFDEYDGFDSANLMRKRFDNGSVGVRGRSSFASRRVDSSVGRSGSGREGLFDRRRNTFVNGTCSASSQEDSSSESDSDEPMRVQGINGVLKVKVNNKTNTLAASINPRDAEIYERPPSSRKAQRRENVVVKPPFRKSNNVDNNSESEESDMSRKSKRKKSEYSKPKKEFNTKSKSTFPELVNPDVREERRGRRGGGTDKQRLRERIKGMLTDAGWTIDYKPRRNQSYLDAVYVNPSGTAYWSIIKAYDALLKQLKDEGVDARPRKDTAAVASVSEEIVNKLARKAKKTRSEMTKKWKQNSSGSDSENKSEGGAYTDTSEERIRSSIKLGGKSTKKGRNGADWDELHKKSKRSLYYNNARPSCGSDSHYLHGRKTKKIGRCTLLVRSSKDKKNPAINGFNPYSGKRTLLSWLIESGVVQLRQKVQYMRRRGAKVMLEGWITREGIHCDCCSKILTVSRFEIHAGSKSCQPFQNIYLESGASLLQCQVRAWNMQKDATNLALHQVDTDGDDPNDDACGICGDGGDLICCDGCPSTYHQNCLGMQVLPSGDWHCPNCTCKFCDAAVASGGKDGNFISLLSCGMCERRYHQLCLNDEAHKVQSFGSASSFCGPKCLELFEKLQKYLGVKTEIEGGYSWSLIHRVDTDSDTNSQMSAQRIENNSKLAVGLAIMDECFLPIVDRRSGVDLIRNVLYNCGSNFNRINYTGFYTAILERGDEIISAASLRFHGMQLAEMPFIGTRHIYRRQGMCRRLFDAIESAMRSLKVEKLVIPAIPDFLHAWTGNFGFTPLDDSVRKEMRSLNTLVFPGIDMLQKPLLHEENIIAPAAAGDAMISEVETEKKSEFTSSVEIGPYAVEGDEFVADAANCYKDILASDEDNILVSVETAMGTICKPKDELSRHFRGEESGISSSPCQITLKSGTKHVLGHICDDTGSSCEDGLTDVNVEADASLLSQEIQQASASFKVENNLSLSISGRGSSDLSSISQEVKSEQTSSNLDGVPSCKDYNILVPGAKLDKSKDDAFADGFLL
Protein: Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas 1) (FRAT-1) (P70339)
Organism: Mus musculus (Mouse)
Function: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15073180}.
Interaction partners:
- Glycogen synthase kinase-3 beta
- Segment polarity protein dishevelled homolog DVL-1
- Axin-1
- GSK-3-binding protein FRAT2
- Segment polarity protein dishevelled homolog DVL-2
- Segment polarity protein dishevelled homolog DVL-3
- FRAT3
Sequence:
MPCRREEEEEAGDEAEGEEDDDSFLLLQQSVTLGGSTDVDQLIVQIGETLQLDAAHDRPASPCAAPGPPPPQVLAALPADKTGTPARRLLRPTGSAETGNPAPPGAVRCVLGERGRVRGRSAPYCVAEISPGASALPQQPGLDGPPGTGKLSTPQPLSGPCRRGWLRNAAASRRLQQRRGSQPETRTGDDDDPHRLLQQLVLSGNLIKEAVRRLHSRQLQLHAKLPAHPFLGPLSAPVHEPPSPGSPRAACSDPGAFMGRAQLRTGDDLLVPGS
Protein: Cycloartenol synthase (EC 5.4.99.8) (Q6BE25)
Organism: Cucurbita pepo (Vegetable marrow) (Summer squash)
Function: Oxidosqualene cyclase involved in the biosynthesis of cycloartenol.
Interaction partners:
Sequence:
MWQLKIGADTVPSDPSNAGGWLSTLNNHVGRQVWHFHPELGSPEDLQQIQQARQHFSDHRFEKKHSADLLMRMQFAKENSSFVNLPQVKVKDKEDVTEEAVTRTLRRAINFYSTIQADDGHWPGDYGGPMFLIPGLVITLSITGALNAVLSTEHQREICRYLYNHQNKDGGWGLHIEGPSTMFGSVLNYVTLRLLGEEAEDGQGAVDKARKWILDHGGAAAITSWGKMWLSVLGVYEWAGNNPLPPELWLLPYLLPCHPGRMWCHCRMVYLPMCYLYGKRFVGPITPIIRSLRKELYLVPYHEVDWNKARNQCAKEDLYYPHPLVQDILWATLHHVYEPLFMHWPAKRLREKALQSVMQHIHYEDENTRYICIGPVNKVLNMLCCWAEDPHSEAFKLHIPRIYDYLWIAEDGMKMQGYNGSQLWDTAFAVQAIISTELAEEYETTLRKAHKYIKDSQVLEDCPGDLQSWYRHISKGAWPFSTADHGWPISDCTAEGLKAVLLLSKLPSEIVGKSIDEQQLYNAVNVILSLQNTDGGFATYELTRSYRWLELMNPAETFGDIVIDYPYVECSSAAIQALAAFKKLYPGHRRDEIDNCIAEAADFIESIQATDGSWYGSWGVCFTYGGWFGIRGLVAAGRRYNNCSSLRKACDFLLSKELAAGGWGESYLSCQNKVYTNIKDDRPHIVNTGWAMLSLIDAGQSERDPTPLHRAARVLINSQMEDGDFPQEEIMGVFNKNCMISYSAYRNIFPIWALGEYRSRVLKPLK
Protein: Transcription factor SOX-14 (Q04892)
Organism: Mus musculus (Mouse)
Function: Acts as a negative regulator of transcription.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
Sequence:
MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATSALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM
Protein: Large ribosomal subunit protein uL22B (60S ribosomal protein L17-B) (O59794)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL28
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein eL29
- Elongation factor 3
Sequence:
MVRYSAAPALETKCAKARGAYLRTHFKNSREVAFTINGMNLKKAFIFLDNVKEHKQAVPFRRFNGGVGRTAQGKEFGVTQARWPVKSVNFFYDLLKNAEANAEAKGLDMDKLIIKHVQVNAAPKQRRRTYRAHGRVTAYLSSPSHIEIIVAEEEEAVPKANDTVSRVSLKQGAKARNLAARKAITSA
Protein: Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Neural phosphoprotein B-50) (pp46) (P17677)
Organism: Homo sapiens (Human)
Function: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14978216}; Peripheral membrane protein {ECO:0000269|PubMed:14978216}; Cytoplasmic side {ECO:0000269|PubMed:14978216}. Cell projection, growth cone membrane {ECO:0000269|PubMed:14978216}; Peripheral membrane protein {ECO:0000269|PubMed:14978216}; Cytoplasmic side {ECO:0000269|PubMed:14978216}. Synapse {ECO:0000269|PubMed:14978216}. Cell projection, filopodium membrane {ECO:0000269|PubMed:14978216}; Peripheral membrane protein {ECO:0000269|PubMed:14978216}. Perikaryon {ECO:0000250|UniProtKB:P07936}. Cell projection, dendrite {ECO:0000250|UniProtKB:P07936}. Cell projection, axon {ECO:0000250|UniProtKB:P07936}. Cytoplasm {ECO:0000250|UniProtKB:P07936}. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes. {ECO:0000269|PubMed:14978216}.
Interaction partners:
- Calmodulin-like protein 4
- Calmodulin-like protein 6
- Calmodulin-like protein 3
- Calmodulin-like protein 5
- Calmodulin-1
- Synapsin-1
- Beta-nerve growth factor
- Brain acid soluble protein 1
- Synaptophysin
- Neurogranin
Sequence:
MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA
Protein: OL-protocadherin (Q9Z1B1)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
MIVLLFFALLWMVDGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARRFQTVANSRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFRVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGGGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAWPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAKLTYSILECQIQGMSVFTYVSINSDNGYLYALRSFDYEQIKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRLDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGDRGGGSGEHLRPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGNGSSTCCGRQARARKKKLSKSDIMLVQSANVPSNPAQVPVEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRSTDAEHNPCGAIVTGYSDQQPDIISNGSILSNEVRLKGKKHHLSSPPSESLL
Protein: Growth hormone (Q0QBC8)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLLLAFTLLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTHIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRAYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLRSCFRKDLHKTETYLRVMKCRRFGEASCAF
Protein: Glutamate receptor ionotropic, kainate 4 (GluK4) (Glutamate receptor KA-1) (KA1) (Q01812)
Organism: Rattus norvegicus (Rat)
Function: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > glutamate >> AMPA.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q16099}; Multi-pass membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q8BMF5}; Multi-pass membrane protein {ECO:0000255}. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q8BMF5}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glutamate receptor ionotropic, kainate 2
- Glutamate receptor ionotropic, kainate 1
- Glutamate receptor ionotropic, kainate 3
- Glutamate receptor ionotropic, kainate 5
- Glutamate receptor ionotropic, NMDA 2D
- Glutamate receptor ionotropic, NMDA 3B
- Glutamate receptor ionotropic, NMDA 3A
- Voltage-dependent calcium channel gamma-4 subunit
- Glutamate receptor ionotropic, NMDA 2C
- Glutamate receptor ionotropic, NMDA 1
Sequence:
MPRVSAPLVLLPAWLLMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVRFQLQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFSQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSRLYASNISDSLFNTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSSLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEASEVSVCQEMMTELRSIILCQDNIHPRRRRSGGLPPQPPVLEERRPRGTATLSNGKLCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWDKTTNSSEPE
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q6FUI3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Endoplasmic reticulum chaperone BiP
- tRNA ligase
- Candida glabrata strain CBS138 chromosome K complete sequence
- Translation initiation factor RLI1
- RING-type E3 ubiquitin transferase
- Transcription factor
Sequence:
MGKFWFWPKHDHDNSTFANQDAKDSEQINSSNSLLEEDFSHILTYEGLEIDPTGAIVDYNIDINEVRRKSQLNTVETPKDTIKEYIPEEYVTNQSKVSHSRYTIAQIILVTDVDGNIHSLNKNNGELQWTLPGSIFPPLIKVEADASLENEIFIIEPFDDGNIYYADVSGGIQKLPINVKQLALSSPIHLRMNSRMGADNESKIDDRIYISSRRSVMYKIDLLSGKILSKFGFESQHDNQSFYSMHEDDQESDLDNSSFNVLLTRTIYEIRTYTKEGASYNITYSAWDENSIQSSNPQFQMLKSDTNKVDYIPLSDKSIVARNQLNGDMKWRTEIPNIAIGVFEILRDTTNGEHIPIQYPLKDVDVPKPDDIKNQVYFNRVDGSSWYALSGTNYPSLVGSASLINNEQDNNNYSVLGSISGVHTLQNPDYNVFYENNRGVLGLPAMSRNTLLLDPPNSVVDSGLPSDLQPPYIDGSYNDEISEQEMRMQLNRLRNVSHGYYEELMSKLSQIIVLSMLGVFALSTFIFIYSRVTGMPVKHMWWNIVNIFRANNNTITAKKVTEEGGQVEKRKRKRGARGGKKNKKSAFISNNDDELSNRVLQVSDKVLGYGSSGTVVYEGKFQERSVAVKRMLVDFYDIASKEIELLSESDEHPNVVRYYCSEETSKFLYIALELCDSNLEQLIETNNVMRHEQRLKDYELVDILAQITQGIAYLHSLNIIHRDIKPQNILISKSKKRLQKPTTGNGNNKTRIMLSDFGLCKKLDFEQSSFKTNIKNAAGTVGWMAPELLIEDENSNKISVSQEIEKIDEVYDPYLRRRLTKAIDIFSLGCVFYYVLSGGSHPFGDKYTREFQIINGKKDFKGLKENMKDKSLVYEAVNILNQLLNHDPSNRPSAEVVLRHPFFWSKAKKLDFLLKVSDRLEIETRDPPSELLTKLENRSRRIIPHHDWCKYLDPEFFENLMKYRKYQKEKVVDLLRAIRNVYHHYNDLPEHIREKMGSIPNGFYDYFSEKYPHLLMEVHFLINKTIKNENLFEEFF
Protein: Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase) (O60760)
Organism: Homo sapiens (Human)
Function: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9353279}.
Interaction partners:
- Prostaglandin-H2 D-isomerase
- Solute carrier organic anion transporter family member 6A1
- Cytochrome P450 1A1
- Maleylacetoacetate isomerase
- Glutathione reductase, mitochondrial
- Cytochrome P450 2E1
- Glutathione S-transferase theta-2B
- Cytochrome P450 3A4)
- Epoxide hydrolase 1
- Prostaglandin E synthase
Sequence:
MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
Protein: Upstream-binding protein 1 (Nuclear factor 2d9) (NF2d9) (Q811S7)
Organism: Mus musculus (Mouse)
Function: Functions as a transcriptional activator in a promoter context-dependent manner. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Functions as a trans-acting factor that regulates the domestic strain CYP2D9 gene through specific association with the regulatory element SDI-A1. Binding to SDI-A1 depends on the type of nucleotide at position 299; binding is abolished by a nucleotide substitution at this position. Modulates the placental expression of CYP11A1 (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MAWVLSMDEVIESGLVHDFDSSLSGIGQELGAGAYSMSDVLALPIFKQEDSSLSLEDEAKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPELSGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKNDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDTPTAYVNNSPSPAPTFTSSQPSTCSVPDSNSSSPNHQGDGAAQASGEQIQPSATTQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCQEQPSSTALQGQPQAAGSGGESGGGTPSVYHAIYLEEMVASEVARKLASVFNIPFHQINQVYRQGPTGIHILVSDQMVQNFQDETCFLFSTVKAENNDGIHIILK
Protein: Testis-specific-RRM-protein (Q24024)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDAGNCASSACLGDCKGDGKTAIKEEGYEHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQKADRRFRFPIFSSVRAGYIPPQPATADSYNYNNPNYNPYLAQSVLPPSAFTNGWAHYVIPMAPKPTPGQNMAASLPSQQLAEHSLNGHGPDMWSSYPKTGIYSAQEWTSSKVAEWGPKAGHKHAQTSTNDRAKIDLKELQAATFNDKLDFGARGDADRMSGAGLGLGLTGGAAVGVGAIKKWPTQDYKVFKPAKSPTNGVIPKIGKEATTPPYGI
Protein: Uncharacterized protein At3g24506 (Q9LV56)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Photosynthetic NDH subunit of subcomplex B 1, chloroplastic
- Photosynthetic NDH subunit of lumenal location 1, chloroplastic
- Protein-tyrosine-phosphatase PTP1
Sequence:
MTPLSISASPSPPWPLLSPPLSSSSLNRAAPSIFSPFSRINHGFSCSFIAVQRFALSRKTRKQLQVVAMAPEEEKLTRRNPLDFPIEWERPKPGRRPDIFPKFSPMKSPLPPPMPYDPPEEEEEEEEKKEEETEDDPEKEDEDQPDNRS
Protein: Anti-dorsalizing morphogenetic protein (Q8UVQ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MLSAMFFAMLSTMMGLSFARPGFFNELEEHLAVESEPKVRSEAIRRLLEVFGMEDPPAALGHKQPPQYMLDLYNTIADVDGVTKDPTLLEGNTVRSFFDKLHSERIEYLFNMSTVAKSEKILTAELHLFKLRPKTSIVLNRHHFCQVSVYQVLDSSKKNVSQGKKLLSSRLVPIHSTGWEVFTITQAVRSWMSDEGSNLGLLVSVRTLAGSQMDLKMVRFASGRDHHHSKQPMLVLFTDDGRRAASLEATSKGSDVSPGGSSQPLPSVPASRRSSRSVDYDERGEKMACQRQPLYVDFEEIGWSGWIVSPKGYNAYHCKGSCIFPLSQNMRPTNHAIVQSIINTLKLNKGIQTPCCVPDKLYSISLLYFDDDENVVLKQYDDMVAGSCGCR
Protein: Carbon monoxide dehydrogenase accessory protein CooC (P31897)
Organism: Rhodospirillum rubrum
Function: Involved in the insertion of nickel into the carbon monoxide dehydrogenase (CODH).
Interaction partners:
Sequence:
MKIAVTGKGGVGKSTIVGMLARALSDEGWRVMAIDADPDANLASAIGVPAERLSALLPISKMTGLARERTGASETTGTHFILNPRVDDIPEQFCVDHAGIKLLLMGTVNHAGSGCVCPEHALVRTLLRHILTKRKECVLIDMEAGIEHFGRGTIEAVDLLVIVIEPGSRSLQTAAQIEGLARDLGIKTICHIANKLASPVDVGFILDRADQFDLLGSIPFDSAIQAADQAGLSCYDLSPACRDKAHALMAALLERVGPTQGVS
Protein: AmpG (G3XCT7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Beta-hexosaminidase
- 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
- N-acetylmuramoyl-L-alanine amidase
- Beta-lactamase
- HTH-type transcriptional activator AmpR
- Anhydro-N-acetylmuramic acid kinase
- N-acetylmuramate/N-acetylglucosamine kinase
- N-acetylmuramoyl-L-alanine amidase
- UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase
- Histidine phosphatase family protein
Sequence:
MTQQSWREALVAYKSPASLALLLLGFAAGLPTMLVFNTLSVWLREAGVARDTIGFASWLGLVYAFKWVWSPMLDQWRLPFVGRLGRRRSWLVFSQVLIALGLLGMALCNPQSHLPWLIGLALLVAFASATQDIAIDAYRLEIAEDSRQAALAACYMTGYRAAILLASAGALILAEWFGSTSLNYSQSAWGLTYALFALLILPGLVTSLLIREPAVDVPIHVNPSRFDFNHQLLSVLLLLILLISLPAMITALLDRAWPRAGLYALLMGICLSPWGRQQIRPVRELLATVRRPLLVAARGKEVPLFDFVHQAVSVMVLIILLVTVTAMCRAYYSGAWPRGTLFLLIAASCLSAPGRLLMAPVLTPITEFVQRYRWQALLLLGLISTYRLSDTVMGVMAGVFYIDMGFSKEVIASVSKVFGVLMTLIGAAAGGVLIARFSILSILFIGGAASAATNLLFAMLAQLGPLHAEALPSHDVISLVMALEPHVLMLVMTITLDNFSGGLAASAFVAYLSSLTNLKFSATQYAMLSSTMLLLPRFIGGYSGTMVESLGYEHFFYVTAVMGIPTLLLIGWLWLRRAPSSEAPAPGHQNAEQH