wanglab/gogpt-training-data huggingface dataset:
Protein: Protein RIK (Rough sheath 2-interacting KH domain protein) (RS2-interacting KH domain protein) (Q9LIA4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Pectin lyase-like superfamily protein
- Transcription factor AS1
- RNA-binding KH domain-containing protein
- Pre-mRNA-splicing factor SYF2
- KH domain-containing protein HEN4
- Protein HIRA
- Disease resistance protein RPP2A
- KH domain-containing protein
- Polygalacturonase QRT3
- Polygalacturonase QRT2
Sequence:
MTEDNDEARVPLSDSSTTNDASRTRQRRKRKWDKPAEQLVAAGVAFPQLLPLGNTMNVPSMSPLLQTLSVPLAVPKVNQPKIQDEVIIAREIVINDAEASLRHRLTKRSTQEDIQRSTGAVVITRGKYRPPNAPPDGEKPLYLHISAAAQLQLKETTERILAVDRAAAMIEEMMKQKSISQIGSVGLQTVKMLSTCVYLGFEADPSSNVAARIRGPNDQYINHIMNETGATVVLRGRGSGSLENQHGDEAQLPLHLLLSGSNPKSIDDAKRLAENLMDTISVEFGASRVSSSKVYGAVPPPQQLISGAPGSDQENQNLISTYGLMTSIPITAPPYAVSSFPVTPATSLYPQFPVMQSLGISNGGPSQPVAGGTSYSGYAGIYPQATPLQQVAQVLKQSISPVISTVPPTMLTATSLSIPSDNASNEMERRPPRKRKFQELPADCKVPEKDKQQSELAMTGDVTPSANRVRSPPSPRSVMPPPPPKTIAPPPSKTMSPPSSKSMLPPPPRSKTMSPLSSKSMLPPPPRFTLTTQRSRLQDNHISVKKPNPVPDTLIKLMEYGDDEDDDDDPDEPLTTRS
Protein: Centrosomal protein 91 kDa (Q86A08)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSYQYDQQHINNESMTHTPNRSRPIFGHTNIPITPIRSTQSPTTPLRPNSGNNNNNNNNGTNNNNNNNETSGNNLNFNHHLKPNGVKFGVTNPKIITTDSNGYSTNINSRTPSKPPSSSSSGNRPLTASQSYIMNETVEYQDAFAKESNDIANNIKTPNRPQHQYQQPQHFTTQPVYQPSYQSNSYDHQNKQQQQQQQQQYQHQNQHQNQNEHQNQNEHHNGVDVENIPPPSSSSSSSQQTPYNRSEEYILGMERQLAFYKSLLKEKSNYKFSNTQASGQPPPPTTTNNYTTTTTQRSYGLNQQPSSPPTTTTTTTTTNENQQQKQSTTNNLKSTTAATTSSGYFIDENDSIIKKRLDEMTDKIYLQEEEISDNLKTIEQQNKTITRLEKEKKKLIESENQLFSDLNRVEREKQMIQNDRDNAIESFEFSSSSFAEEKSRLDDQIRQLQNQVKQMNRSLEECNSTIDEWDQEYQKLQSAYTQLSNQEQKYKQEINQISVISQDMNQLKLDYDQSIQQSNELSLELKEKNQKTKELIKECDDLKLKVSQQQQQFDQLTNKSKMYIEYRDKQINDLTKTTDRQIQQLNEKIQQLNDIIITKDQSLATCNLERKKQLNDFALNYKKLQEQYEIVDVDKSLQINEKDSQLNQALIDLKYLHDLVDKLSPGFFKNFPNNRNQLQQQPQPPSTQQTRIPPISTQQTSHGGVRDPFSPSRQVPQPQPQPQPQPQPQPQPQPQSNINNPQRRNLNGNSGNSSSSNGAFSTSQLRTNGGPTSSNGPNTPNRNIGFDGRINQNPSTVRR
Protein: Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) (Presenilin-stabilization factor) (Q96BI3)
Organism: Homo sapiens (Human)
Function: Non-catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Required for normal gamma-secretase assembly. The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12522139}; Multi-pass membrane protein {ECO:0000269|PubMed:25043039, ECO:0000269|PubMed:26280335, ECO:0000269|PubMed:26623517, ECO:0000269|PubMed:30598546, ECO:0000269|PubMed:30630874}. Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:12522139}; Multi-pass membrane protein {ECO:0000269|PubMed:25043039, ECO:0000269|PubMed:26280335, ECO:0000269|PubMed:26623517, ECO:0000269|PubMed:30598546, ECO:0000269|PubMed:30630874}. Note=Predominantly located in the endoplasmic reticulum and in the cis-Golgi. {ECO:0000269|PubMed:12522139}.
Interaction partners:
- Nicastrin
- Gamma-secretase subunit PEN-2
- Presenilin-2
- Presenilin-1
- Transmembrane emp24 domain-containing protein 10
- Amyloid-beta precursor protein
- Neurogenic locus notch homolog protein 1
- Gamma-secretase subunit APH-1B
- Neurogenic locus notch homolog protein 3
- Disintegrin and metalloproteinase domain-containing protein 10
Sequence:
MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQRSLLCRRQEDSRVMVYSALRIPPED
Protein: Zinc finger protein 792 (Q3KQV3)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MAAAALRDPAQGCVTFEDVTIYFSQEEWVLLDEAQRLLYCDVMLENFALIASLGLISFRSHIVSQLEMGKEPWVPDSVDMTSAMARGAYGRPGSDFCHGTEGKDLPSEHNVSVEGVAQDRSPEATLCPQKTCPCDICGLRLKDILHLAEHQTTHPRQKPFVCEAYVKGSEFSANLPRKQVQQNVHNPIRTEEGQASPVKTCRDHTSDQLSTCREGGKDFVATAGFLQCEVTPSDGEPHEATEGVVDFHIALRHNKCCESGDAFNNKSTLVQHQRIHSRERPYECSKCGIFFTYAADLTQHQKVHNRGKPYECCECGKFFSQHSSLVKHRRVHTGESPHVCGDCGKFFSRSSNLIQHKRVHTGEKPYECSDCGKFFSQRSNLIHHKRVHTGRSAHECSECGKSFNCNSSLIKHWRVHTGERPYKCNECGKFFSHIASLIQHQIVHTGERPHGCGECGKAFSRSSDLMKHQRVHTGERPYECNECGKLFSQSSSLNSHRRLHTGERPYQCSECGKFFNQSSSLNNHRRLHTGERPYECSECGKTFRQRSNLRQHLKVHKPDRPYECSECGKAFNQRPTLIRHQKIHIRERSMENVLLPCSQHTPEISSENRPYQGAVNYKLKLVHPSTHPGEVP
Protein: Exocyst subunit Exo70 family protein (Q9LIA2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Exocyst complex component SEC5A
- Exocyst complex component SEC8
- Exocyst complex component SEC3A
- Exocyst complex component SEC6
- Exocyst complex component EXO84C
- Exocyst complex component EXO84A
- Exocyst complex component SEC15B
- Exocyst complex component SEC10a
- Exocyst complex component EXO84B
- Exocyst complex component SEC3B
Sequence:
MGEFEVDGEEKLIVAAKYLVKELRSGKSLTKNAKNVLGNLLLELSRVVIAEDTQDRDEEDEIGEIEERLNVVSEKIMTREVDESMIWDLGSDEGNLYLDAVNELRSLIDRLDGSEELSLRKAHDVLQIAMARLEDEFKHLLVENRLPFELEHSSFRSIEADHGVEEESMASFGAASTEDLILGSNNDSRRNSGDVVVDLVNPDVILDLKNIANTMIASGYDRECIQVCTMVRKDALDEFLYNHEVEKLSIEDVLRMDWATLNTNIKKWVRVMRDIVQVYLLSEKSLDNQIFGDLNEIGLTCFVDTVKAPMMQLLNFGEAVSLGPRQPEKLLRILEMYELASELLPEIDALFLDHPGSSVRTEYREVMRRLGDCARTTFLEFKSAIAADVSSHPFPGGAVHPLTNYVMNYLMALTDFKHTLDSLLMEHDDAEDLTIPPSPDIINPVMVEEESTYENSSSPEKFLAMTRHFYSITSVLEANLQEKSKLYKDVSLQHIFLLNNIHYMTRKVLKSELRHIFGDKWNRKHTWKFQQQATEYERATWLPVLSFLKDDGSGSGPGSGSGSGSKNLRPRERFQGFNTAFEEVYKAQTGWLISDEGLREDVRTKASMWVIQAYWTFYSRHKNSVSERYIKYTTDDIERLLLDLFAGSSKSLNNSYRR
Protein: Solute carrier family 28 member 1 (cDNA FLJ58165, highly similar to Sodium/nucleoside cotransporter 1) (B7Z3L6)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MENDPSRRRESISLTPVAKGLENMGADFLESLEEGQLPRSDLSPAEIRSSWSEAAPKPFSRWRNLQPALRARSFCREHMQLFRWIGTGLLCTGLSAFLLVACLLDFQRALALFVLTCVVLTFLGHRLLKRLLGPKLRRFLKPQGHPRLLLWFKRGLALAAFLGLVLWLSLDTSQRPEQLVSFAGICVFVALLFACSKHHCAVSWRAVSWGLGLQFVLGLLVIRTEPGFIAFEWLGEQIRIFLSYTKAGSSFVFGEALVKDVFAFQVLPIIVFFSCVISVLYHVGLMQWVILKIAWLMQVTMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGVRAEVLTTFALCGFANFSSIGIMLGGLTSMVPQRKSDFSQIVLRALFTGACVSLVNACMAGILYMPRGAEVDCMSLLNTTLSSSSFEIYQCCREAFQSVNPEFSPEALDNCCRFYNHTICAQ
Protein: Rap guanine nucleotide exchange factor 1 (A0A8I5ZUL6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSQKEKRPGPHVPSFDSFKKEVLAKRPHHSHKNHSLSCPSSNSQTSVLSDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSKTPEKPVSKNLCWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQTDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGQPELPLTEREMEILNKTSVSPSTELLPDSTSEEVAPPKPPLPGIRVVDNSPPALPPKKRQSAPSPTRVAVVAPMSRAVSGSSLPVGINRQDFDVECYTQRRLSGGSRSCGGESPRLSPCSSTGKLSRSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQTPPQAACNLSPLPESMGESGPPFVGYSFQLPLGSCLQQDGQQTDTPPALPEKKRRSAVSQTTDSSGCRVSYERHPSQYDNISEDDLQNPAQPVSYPPFAAILPFQQGASSTPVEFVGDFSVPESAGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQSEHIYQQKNKMLMEVYGFSDSFCGSDSTQELAPPPALPPKQRQLEPPSGKDGHPRDLSVSSASGKDSRENGERSPKSLDALESAQSEEEVDELSLIDHNEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQCRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILKLLMELVFRLVCSGELSLARVLRKNILDKVDQKKLLRCAHSDQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSVIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQRQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQVHYEIRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
Protein: Uncharacterized protein (Q38AF6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DDRGK domain-containing protein 1
- Ubiquitin-like modifier-activating enzyme 5
Sequence:
MSELELSELIRKFQAIQRQDIPNQITERNVVEIVNVLQRKKFVDLLFTVDGKEYLTWDQLRREVIDEVHANGGRMNVTDLPGLLTVHMIHIERVLPEVLEEPNIRLEAAELMTDEYLDSTVSAAQDVLKEKGFVAVSEFARIHRFTSLFAQNLLTGAVESGRLRAVLQGGALHTKQFVGAQKVVLRAGLLAATEPVNLTTFFERHNLFAPLVDVLIEAVRNDLPGKIEGRVYIPTYFEQDRANEVENVYLSNGFIEYALLHRKGITQAREFLSTKYNPVMEATAQGDAPKRRTRRVQAASTANTESPSVARSEKYPNAGHALSACFLSDRFLANLVVLEDLAHGDALVVDLSTHLPLSVDFEKDSDILLRRLRELHPIVTSCTLLDCGVLLHESVLPTVKKRLESSYDLQIRESGAKGRKSKVSREFGEEEEEILLRAVADVTGLPLEQYQDVLAELTSEWKVVAQEVYSELAAAAEQHVSVDWKRMRTNLQSSLGTAWCGMVIAEKGVLWATTKFDETSCVALNRHLLTDRAFALLRDILLNEGLDSAGVYECVCEALMVKEDQQKQQPPTAALLQKALKALPEQQRQSLSPLVDAAMGKSVETFTKLLRDMSCTAQIAVSGFHQLNKKVERETLASMKQEVKKRVEEDTFTTDTARSGALFALLCSLLIHSRFHVHVDLPGRAVGGAVTCLAAEAMGVAELLKECNQIITGAISGKHSLSDDDVEKLETLRRLVLEDA
Protein: Cysteine-rich receptor-like protein kinase 10 (Cysteine-rich RLK10) (EC 2.7.11.-) (Receptor-like protein kinase 4) (Q8GYA4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Leucine-rich repeat
- Carbohydrate-binding X8 domain superfamily protein
- Carbohydrate-binding X8 domain superfamily protein
- At2g03505
- Carbohydrate-binding X8 domain superfamily protein
- Dihydrofolate reductase
- F-box protein At5g18160
- Methyltransferase-like protein 2
- Non-specific lipid transfer protein GPI-anchored 11
Sequence:
MRRNTDQESPIMSYYSSFFFLFLFSFLTSFRVSAQDPTYVYHTCQNTANYTSNSTYNNNLKTLLASLSSRNASYSTGFQNATVGQAPDRVTGLFNCRGDVSTEVCRRCVSFAVNDTLTRCPNQKEATLYYDECVLRYSNQNILSTLITTGGVILVNTRNVTSNQLDLLSDLVLPTLNQAATVALNSSKKFGTRKNNFTALQSFYGLVQCTPDLTRQDCSRCLQLVINQIPTDRIGARIINPSCTSRYEIYAFYTESAVPPPPPPPSISTPPVSAPPRSGKDGNSKVLVIAIVVPIIVAVLLFIAGYCFLTRRARKSYYTPSAFAGDDITTADSLQLDYRTIQTATDDFVESNKIGQGGFGEVYKGTLSDGTEVAVKRLSKSSGQGEVEFKNEVVLVAKLQHRNLVRLLGFCLDGEERVLVYEYVPNKSLDYFLFDPAKKGQLDWTRRYKIIGGVARGILYLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGLDQTEENTSRIVGTYGYMSPEYAMHGQYSMKSDVYSFGVLVLEIISGKKNSSFYQTDGAHDLVSYAWGLWSNGRPLELVDPAIVENCQRNEVVRCVHIGLLCVQEDPAERPTLSTIVLMLTSNTVTLPVPRQPGLFFQSRIGKDPLDTDTTSKSLLGSVDDASITDIHPR
Protein: Histone acetyltransferase GCN5 (EC 2.3.1.48) (Histone crotonyltransferase GCN5) (EC 2.3.1.-) (Q03330)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Histone acetyltransferase that acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K9ac, H3K14ac, H3K18ac, H3K23ac, H3K27ac and H3K36ac, with a lower preference histone H4 to form H4K8ac and H4K16ac, and contributes to H2A.Z acetylation. Acetylation of histones gives a specific tag for epigenetic transcription activation and elongation. Operates in concert with certain DNA-binding transcriptional activators such as GCN4 or HAP2/3/4. Its acetyltransferase activity seems to be dependent on the association in different multisubunit complexes. Functions as histone acetyltransferase component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8). SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation. The ADA histone acetyltransferase complex preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B, leading to transcription regulation. SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus. In addition to histone acetyltransferase, can use different acyl-CoA substrates, such as (2E)-butenoyl-CoA (crotonyl-CoA) and is able to mediate histone crotonylation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- SAGA complex/transcription factor TFIID complex subunit TAF9
- SAGA complex/transcription factor TFIID complex subunit TAF12
- SAGA complex/transcription factor TFIID complex subunit TAF10
- SAGA complex subunit SGF73
- SAGA complex subunit SPT20
- SAGA complex subunit NGG1
- SAGA complex subunit SPT7
- SAGA complex/NuA4 acetyltransferase complex subunit TRA1
- SAGA complex subunit ADA2
- Ubiquitin carboxyl-terminal hydrolase 8
Sequence:
MVTKHQIEEDHLDGATTDPEVKRVKLENNVEEIQPEQAETNKQEGTDKENKGKFEKETERIGGSEVVTDVEKGIVKFEFDGVEYTFKERPSVVEENEGKIEFRVVNNDNTKENMMVLTGLKNIFQKQLPKMPKEYIARLVYDRSHLSMAVIRKPLTVVGGITYRPFDKREFAEIVFCAISSTEQVRGYGAHLMNHLKDYVRNTSNIKYFLTYADNYAIGYFKKQGFTKEITLDKSIWMGYIKDYEGGTLMQCSMLPRIRYLDAGKILLLQEAALRRKIRTISKSHIVRPGLEQFKDLNNIKPIDPMTIPGLKEAGWTPEMDALAQRPKRGPHDAAIQNILTELQNHAAAWPFLQPVNKEEVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFNNKVKEIPEYSHLID
Protein: tRNA threonylcarbamoyladenosine biosynthesis protein TsaE (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE) (A0A0H2URN5)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLAKGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWGNLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV
Protein: Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22) (P80723)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Associated with the membranes of growth cones that form the tips of elongating axons.
Interaction partners:
- Myristoylated alanine-rich C-kinase substrate
- Neuromodulin
- Wilms tumor protein
- Calmodulin-like protein 6
- Calmodulin-like protein 4
- Calmodulin-like protein 5
- Calmodulin-like protein 3
- Cadherin-18
Sequence:
MGGKLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEPKPVEAPAANSDQTVTVKE
Protein: CD99 antigen (Paired immunoglobin-like type 2 receptor-ligand) (PILR-L) (CD antigen CD99) (Q8VCN6)
Organism: Mus musculus (Mouse)
Function: Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- CD99 antigen-like protein 2
Sequence:
MARAAMEAAATVVLALALLGAAARGAASDDFNLGDALEDPNMKPTPKAPTPKKPSGGFDLEDALPGGGGGGAGEKPGNRPQPDPKPPRPHGDSGGISDSDLADAAGQGGGGAGRRGSGDEGGHGGAGGAEPEGTPQGLVPGVVAAVVAAVAGAVSSFVAYQRRRLCFREGGSAPV
Protein: RHOMBOID-like protein 3 (AtRBL3) (EC 3.4.21.105) (Q9LYP1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:22738221}; Multi-pass membrane protein {ECO:0000255}. Note=Not localized in cytosol, mitochondria or chloroplast. {ECO:0000269|PubMed:22738221}.
Interaction partners:
- Rhomboid-like protein 16, chloroplastic
- Rhomboid-like protein 14, mitochondrial
- Rhomboid-like protein 17, chloroplastic
- Rhomboid-like protein 15
- RHOMBOID-like protein 13
- Rhomboid-like protein 20
- Rhomboid-like protein 18
- Rhomboid-like protein 19
- Protein SLOW WALKER 2
- RHOMBOID-like protein 12, mitochondrial
Sequence:
MAVGDDDLENRMSAKDRGIGSRGGDRNRIGPPPLPVALSSSTEFGDNALSSRWTSWLVPMFVVANVAVFVVAMFVNNCPNHFESHRLRGHCVAKFLGRLSFEPLRTNPLFGPSSHTLEKLGALEWSKVVEKKEGWRLLTCIWLHAGVIHLGANMLSLVFIGIRLEQQFGFVRIGVIYLLSGIGGSVLSSLFIRNSISVGASGALFGLLGSMLSELFTNWTIYSNKIAALLTLLFVILINLAIGILPHVDNFAHVGGFVTGFLLGFILLARPQFKWLAREHMPQGTPLRYKYKTYQYLLWLLSLVLLIAGFVVALLMLFRGENGNDHCRWCHYLRCVPTSSWRCDDV
Protein: Histocompatibility 2, M region locus 3 (MHC class I antigen H-2M3) (Q31093)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Beta-2-microglobulin
- H-2 class II histocompatibility antigen, A-B alpha chain
- H-2 class II histocompatibility antigen, A beta chain
- T-cell surface glycoprotein YE1/48
- Class II histocompatibility antigen, M alpha chain
- Tapasin
- H2-O alpha
- H-2 class I histocompatibility antigen, D-37 alpha chain
- H-2 class II histocompatibility antigen, E-B beta chain
- H-2 class I histocompatibility antigen, K-B alpha chain
Sequence:
MGSSSNRALLHMVVVSLAVTQTGSGSHSLRYFHTAVSRPGRGEPQYISVGYVDDVQFQRCDSIEEIPRMEPRAPWMEKERPEYWKELKLKVKNIAQSARANLRTLLRYYNQSEGGSHILQWMVSCEVGPDMRLLGAHYQAAYDGSDYITLNEDLSSWTAVDMVSQITKSRLESAGTAEYFRAYVEGECLELLHRFLRNGKEILQRADPPKAHVAHHPRPKGDVTLRCWALGFYPADITLTWQKDEEDLTQDMELVETRPSGDGTFQKWAAVVVPSGEEQRYTCYVHHEGLTEPLALKWGRSSQSSVVIMVIVASLVLLGGVITIVVVCKRRGAGER
Protein: PhoP/Q and low Mg2+ inducible outer membrane protein H1 (G3XD11)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Two-component response regulator PhoP
- Two-component sensor PhoQ
- Outer membrane porin F
- Outer membrane protein OprG
- Anaerobically-induced outer membrane porin OprE
- Copper transport outer membrane porin OprC
- Sn-glycerol-3-phosphate transporter
- Porin D
- Cytochrome c-type protein
- Glycine zipper 2TM domain-containing protein
Sequence:
MKALKTLFIATALLGSAAGVQAADNFVGLTWGETSNNIQKSKSLNRNLNSPNLDKVIDNTGTWGIRAGQQFEQGRYYATYENISDTSSGNKLRQQNLLGSYDAFLPIGDNNTKLFGGATLGLVKLEQDGKGFKRDSDVGYAAGLQAGILQELSKNASIEGGYRYLRTNASTEMTPHGGNKLGSLDLHSSSQFYLGANYKF
Protein: Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (E7ETE2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVREVDVRREDLVEEIKRRTGQPLCIC
Protein: Urease subunit alpha (EC 3.5.1.5) (Urea amidohydrolase subunit alpha) (A0A0H3LAR3)
Organism: Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01953, ECO:0000256|PROSITE-ProRule:PRU00700}.
Interaction partners:
Sequence:
MARLSRERYAQLYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGAPDTVITGAVIIDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVHLICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFAESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQPVLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF
Protein: Epididymis luminal protein 57 (Epididymis secretory protein Li 27) (Serpin peptidase inhibitor, clade B (Ovalbumin), member 1, isoform CRA_a) (V9HWH1)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP
Protein: deoxyribose-phosphate aldolase (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (E9PML7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSAHNRGTELARWLENPTTQKTKPKTNNPQADLSWISKIQVNHPAVLRRAEQIQARRTVKKEWQAAWLLKAVTFIDLTTLSGDDTSSNIQRLCYKAKYPIREDLLKALNMHDKGITTAAVCVYPARVCDAVKALKAAGCNIPVASVAAGFPAGQTHLKTRLEEIRLAVEDGATEIDVVINRSLVLTGQWEALYDEIRQFRKACGEAHLKTILATGELGTLTNVYKASMIAMMAGSD
Protein: Low affinity heme transporter str3 (Siderophore iron transporter 3) (Q92341)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Low affinity heme transporter involved in the assimilation of exogenous heme during conditions of low cellular iron.
Subcellular location: Cell membrane {ECO:0000269|PubMed:29549126}; Multi-pass membrane protein {ECO:0000269|PubMed:29549126}.
Interaction partners:
- Uncharacterized trans-sulfuration enzyme C23A1.14c
- Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- L-ornithine N
Sequence:
MEAKETHSISDHEVELQDAKPEEKSENGNFVFEKAFSSDEEKGSGYNTNETYSKMDNSLQHRGVSKIEAVRDSIYQNKRGMYLAYAFGIAILACSWASAIQSSTTYSYQVYATASFNRTSMISTLEIATAIISSVCKPILGKFSDITSRPMTYTLVLLFYVIGFIVVASSSTISAYVIGSVFISIGSSGLDYLNTLVVGDLTSLKWRGFMTALLSTPYIATVWFTGFIVQGIIDSNWRWGYGMFAIIMPAVMTPAVIILMYLERQANKDENIKKIINYQTEEKNKNKQSKWQKLWKAVLEVDLFGLILLGVGWSILLLPFSLTSYAKNGWKNPSMIAMMVVGGVILIAYSGYEMFIAPYPSCPRRVMNRTFITAVIIDFFYYLAGYLQSMYFTTYTWILYDWSYRDWTYFNNTMTIALCVFGVFAGAMHRVFHRYKYLQIIGLVIKIVGYGILIRPNFAATGKVDLAWSLILIGMGGSFSVVGSQVSCQASVPHQDLAIASSLLPLYTNIGGAIGAAIASPIFSNKVPKYLREYLPSSINDTQVYNFYSDSSLIREYPVGTEIRDGAIKAYSRSMFFLLVPAVSLSFIPLAAAFWQSNFYLGNQQNAVEGDQDHKKKGDKETTQEEKIII