wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein YCR016W (P25617)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Regulator of rDNA transcription protein 14
- Ribosome assembly protein 3
- UPF0642 protein YBL028C
- 25S rRNA
- H/ACA ribonucleoprotein complex subunit CBF5
- rRNA-processing protein FCF2
- Protein HGH1
- Nucleolar protein 13
- Uncharacterized protein YNL050C
- Protein BCP1
Sequence:
MSENHVPAWKRIALKRQTISSGDESKEKGQSNLIDDDPLNITTHLSTGNLTKKEKKRIINGESKSSTKKGKRVSKPGTKKKEKLSKDEKNSKKNKILKDQLRYLIEFFRTKSESKFPTGILELESVKENYGDSLIKDEPSESGVVEVWKFSKQKQNWLIKHFFNLDEIPSVYNDLLLLYFRDLQGKSKEELISKCKGKLKQWNDYVEDQETKIKALIAEDKASEPINGEEKEEGEKDGNAEQGKQKEVQDEQEEVQMPNKELVQRSLKLLEIWKNDDSEQIELKNFFVDV
Protein: Biotin synthase (EC 2.8.1.6) (P9WPQ7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
Interaction partners:
- Dethiobiotin synthetase BioD
- Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
- 8-amino-7-oxononanoate synthase 1
- Biotin--[acetyl-CoA-carboxylase] ligase
- Biotin synthase auxiliary protein
- Putative 8-amino-7-oxononanoate synthase 2
- Uncharacterized protein Rv1591
- Probable biotin sulfoxide reductase BisC
- Glutamine-dependent NAD
- 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Sequence:
MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL
Protein: Polyadenylate-binding protein (PABP) (Q6PHQ9)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU362004}.
Interaction partners:
- Bcl-2-like protein 2
- Polyadenylate-binding protein 2
- Eukaryotic translation initiation factor 4E
- Ataxin-2
- Probable ATP-dependent RNA helicase DDX6
- PAN2-PAN3 deadenylation complex catalytic subunit Pan2
- La-related protein 1
- Ataxin-2-like protein
- Regulator of nonsense transcripts 1
- Eukaryotic initiation factor 4A-I
Sequence:
MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVMKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDSSGKSKGFGFVSYEKHEDANKAVEEMNGKEMSGKAIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPASAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSALRQSGPRPALRHLAPTGNAPASRGLPTTAQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVPNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGTVAAATS
Protein: Thymine dioxygenase JBP1 (EC 1.14.11.6) (J-binding protein 1) (Thymidine hydroxylase JBP1) (P86937)
Organism: Trypanosoma brucei brucei
Function: Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Also specifically binds to base J-containing DNA (J-DNA). Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis. Thymine dioxygenase activity and J-DNA-binding are independent functions.
Subcellular location: Nucleus {ECO:0000269|PubMed:15694344}.
Interaction partners:
Sequence:
MRRQVKKVLREKADDSMKPGWDVYQPSNDVVYAFNHYMQGSQIDAEAREKAEKAFQEAVKKHPFHNNADHAVDFHGTTVFRNAKGKVCGVLIPKALPSFATSMAADVLECAVARTSLRSALFGGVSPNSGIAGYFDYRGTPVELKCRKTSFTYEHTKEWRSVFPMIDYTSAIYKAALPDHWKAQDAAVPDVVRIHGSPFSTLTVNERFRTASHTDNGDFDNGYGVLAVLKGEYSGLSLALDDYGVCFNMQPTDVLLFDTHLFHSNTELEAKEANATWNRLSCVFYYRAALGEQPCVEEYRRRLKKAKEEKSTSLSFNHIEQKDNGENTNKPAPVYPVPLTPFSCAASAWALRGCAAAMLTRLHGLVRENASLMTELFGEPVEVADGLPRRAPEEIIPVHKHTNVQMHYLGGFSEKGDILNEAMNKRHYLDKENLQKMFGEEFVNIWTQSRTHWLQLVKKEWEHQKETNPTRTRFSWNNTSAMNFAFFDLCDVAKQLMCGAFGDREVNKKEEQSFWGMFAAHLDNACINEIGMLQGSMGMHKLNVKLKDYNFGGTRYLKDMPPEEQERRRRRRLEIEQARRRAPICNSESGDWLRNEAFDYQTEDVAVNYEREQWITPENNAKRFGFPERGVYGAEGAATGTISVLIVLPKPTNHRQKTCELPTSREADRIMKNPAAQRLLCAKPCNIGLSTSSNKSRTVLCGNIRIDKVFDGGSVGGKMYDFVIMRHLLAATTGEREPLECLVRWTSLARYCTFVVEVDLLDRHHYILKSEIGEEYSAVSEICFSALYSATYARDKVNLRTTPCLLSFIDKSGNMLESRFKFNGSPLNTVAFVVRRREK
Protein: Oocyte maturation, alpha (F6ZJR3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRAVSLRARSLKVNRELVKNVYLPSQ
Protein: Inner membrane protein YrbG (P45394)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
- Arabinose 5-phosphate isomerase KdsD
- Lipopolysaccharide export system ATP-binding protein LptB
- Lipopolysaccharide export system protein LptC
- Lipopolysaccharide export system protein LptA
Sequence:
MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLRRELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTREQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDYSVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPILVE
Protein: Proton-coupled zinc antiporter SLC30A8 (Solute carrier family 30 member 8) (Zinc transporter 8) (ZnT-8) (P0CE46)
Organism: Rattus norvegicus (Rat)
Function: Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion.
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:19095428}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q8IWU4}; Multi-pass membrane protein {ECO:0000255}. Note=Associated with insulin and glucagon secretory granules. {ECO:0000250|UniProtKB:Q8IWU4}.
Interaction partners:
- Glutamate decarboxylase 2
- tRNA-t
- Hematopoietically-expressed homeobox.
- ATP-binding cassette sub-family C member 8
- Transcription factor 7 like 2
- Receptor-type tyrosine-protein phosphatase-like N
- Insulin-1
- Insulin-2
- Zinc transporter ZIP6
- ATP-sensitive inward rectifier potassium channel 11
Sequence:
MEFLERTYLVNDQATKMYAFTSDRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSSKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPSKRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTLILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSVLALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVATAASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD
Protein: RNA binding motif protein 6 (Q3ULB0)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDYRGGDGTPMDYRGRETPHMNYRDRDSHTVDFRSRDVPPTDFRGRGTYDLDFRGREGSHSDFRGRDLSDLDFRSRDQSRSDFRNRDVSDLDFRDKDGTQVDFRGRGSATTDLDFRNRDTPHSDFRGRHRTRTYQDFRGREVGPCMEFKDREMPPMDPKVLDYIQPSPQEREHSGMNMNKREESIHDHAMERPAFGVQKGEFEHSETREGETQSGTFEHESQSDFQNSQSPVQEQDKPKLSGGEQQSSDAGLFKEEGDLDFLGQQDTDYRSIEYCDVDHRLPGNQIFGYGQSKSFSQGKMSRDAQQDLQDQDYRTGPSEEKPNRLIRLSGVPENATKEEILNAFRTSDGIPVKDLQLKEYNTGYDYGYVCVEFSLLEDAIGCMEANQGTLMIHDKEVTLEYVPSPDFWYCKRCKASTGGHQSSCSFCKGPKEEVKQELVSYPQPQKTSIPVPSEKQPNQPRPADKEHELRKREEGQESRLGHQKRDTERYFPHSRREGLTFRRDREKEPWSGDSRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVHLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGNRNSDWSSDTNRQGQQSSSDCYIYDSTTGYYYDPLAGTYYDPNTQQEVYVPQDPESPDEEEIKEKKSTSQGKSNSKKETSKRDGKEKKDRGMTKFQESTSEGKPPLEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQAPPVQPRTAQPREEMTKKENEDDKLTDWNKLACLLCRRQFPNKEVLTKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGRFKEKGNDRREKLQSFDSPERKRIKYSRETDSDRNPVDKEDTDTSSKGGCAQQATGWRKGAGLGYSHPGLGSSEEIEGRMRGPGGGPPGRTSKRQSNETYRDAVRRVMFARYKELD
Protein: At5g13560 (Structural maintenance of chromosomes protein) (Q8GY46)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Homogentisate 1,2-dioxygenase
Sequence:
MSWLRTAVNKAVEVGNRKNITRTVKNYADSVVQHAGQAVAEGAKLFQDRIGVGAYKSVHQTIQRLEEAAVSYRGQERALLITRWLSVLKEIDRATDSSLKDKQLSSEEQLASDEAKKREWVLYYDPDIGGEPLNFRDVFLQSQALEGIVLSMIIEPPHDEEITLLLEMFGLCLNGGKEVHDAIVSSMQDLATVFSSYKDEVLVKQDELLQFAQNAITGLKINAEMLRIDAEASDLRKKLEKMNASQIPQESEDKEHKETPLTIEAFKETLAKIRLCSRLEGLLIRKRQLSNGDSPDIHAQKVDKLRVLLESLANSTSKAEKRISENRLQKEEALKARVVKANETGEKEKELGAEIAQLEKQRDELEADLKRVNLSLAAAQARFRNATEERDQFGEANNQIIAHLKTKDDDLSKSVVACKKEAEVIKTWINFLEDTWLLQCSHIETKDKQTLDELEKHEDYFSDVALNILSVYKKEVAPLISRIENYVENLKNLGPGSEKPPNADQGDNQVSNPRKILEEEYIDYETKIITTFSIVDNVKEQFQVLQSKLDKKDDRRVKELFDDMEKMRQQFESIARPTLEIEIPSPRSSVTSPKSSATSPKSPKPSSSSMNASTESTQTQKPELSNSPQAPNPAAGSSQEFNPEAELAELESEFGKVARDYSADEVDGWEFDELEKELQ
Protein: Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform E (EC 2.7.1.68) (Q9W1Y3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Phosphatidylinositol 4-kinase alpha
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- Phosphatidylinositol 4-kinase beta
- Phosphatidylinositol-3-phosphatase SAC1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- phosphatidylinositol 3-kinase
- phosphoinositide 5-phosphatase
- Phosphatidylinositol 5-phosphate 4-kinase, isoform A
- Pi3K21B, isoform B
Sequence:
MASGDGDTINTIDMDSSSASQAKLAEPSNASTDHVGNSSPDLGNRPNRASSKADKERKIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAESEPIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNHRKFRTLVTSYIALKHSPSKRKSLSKAIQRSIDSDNEVASRPVHASHSHSSGKIHQPAKPPTTEPTPAGAAGGAERGATALGPATTSGASERAPPPVKQRTPAASNLKTRVPPPVPPRGSPRRKDAQDRTTPGTTPSCSSTPPPAFDDISEDSSNKNSSSSIGRRSHHHHHHHQQSQQHQQSYYLDRKMNIGPAYRGSYKEDIVSVSEVHLDTLLAVDTSSSSQYGSRGGLAWTPPASGEGSTPTWTEGTPSFTDSSSSGDLDQLT
Protein: Ankyrin repeat domain-containing protein 61 (A6NGH8)
Organism: Homo sapiens (Human)
Interaction partners:
- Radial spoke head 10 homolog B
Sequence:
MGNITRKGSRDLVVDSAKSLEDGPSAALHSKLYEAIMREDCTTIEVLLRNHPVNQPITILPNSASNRLLLTQPTESIIPIHLAAKYHKAQSLLCLLRHGADPEVRDTTGLTTLNLMLLHWPVTSTTWAKPGNRTHRILTDIQNSSITCLRILCAHGAQVNTQGEISNKRSPLHLAIAYGCYPVLSILTQNGADVNAINEASMTPLHMAANMLNKEMMETLIAYGANVNCAVSSTGNTPLKLAVCTASSKAGRLLGAGVSCIRLLLTHGAKVNAQDYKGQTAIHEACFGGREAIINLLLEFEANVNILTRNGESPIYMYLQRSCNVRDTALLARLLYHTYPLRMTNNQGILPAGIMLPEFRLLRDTLIKQSQKPLSLQGICKRNIRNIYGEKYKQHLKQFLPVTIWNSVYCCYDLAYTS
Protein: Esterase TesA (EC 3.1.1.1) (Q9HZY8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Esterase that exhibits the highest activity towards Tween detergents and p-nitrophenyl esters of short acyl chain length. Also displays a low thioesterase activity towards palmitoyl-coenzyme A, but is not active towards acetyl-coenzyme A.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- ABC3 transporter permease C-terminal domain-containing protein
- Acyl-CoA thioesterase 2
- Alpha/beta hydrolase
- Esterase EstA
- Probable ATP-binding component of ABC transporter
- Probable thioesterase
- ChoE
- Enoyl-[acyl-carrier-protein] reductase FabI
- Glycerol-3-phosphate acyltransferase
- Phosphate acyltransferase
Sequence:
MRALLLSGCLALVLLTQQAAAQTLLVVGDSISAALGLDTSQGWVALLQKRLADEGYDYRVVNASISGDTSAGGLARLPALLAEEKPALVVIELGGNDGLRGMAPAQLQQNLASMAQKARAEGAKVLLLGIQLPPNYGPRYIEAFSRVYGAVAAQEKTALVPFFLEGVGGVQGMMQADGIHPALAAQPRLLENVWPTLKPLL
Protein: glycogenin glucosyltransferase (EC 2.4.1.186) (A0A0B4LG29)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSKFAWVTLTTNDTYSLGALVLAHSLKRAKTAHQLAVLVTPNVSQAMRDRLKEVYNVVQEVNVLDSQDAANLALLSRPELGVTFTKLHCWRLVQFEKCVFLDADTLVLQNCDELFEREELSAAPDVSWPDCFNSGVFVFKPSVDTFAQITEFAVKNGSFDGGDQGLLNQFFADWSTADIKKHLPFVYNVTAYASYCYLPAFKQFRDKIKILHFAGKLKPWLIQFNSETKVASVSSEYAHAQDLIQLWWNIFCENVIQSLSTEMQTPGNVASDRPAGEMAQGSTTLEAGLAGALSQLRIGQQRTPEQEAYENQMRRQCWESGQIDYTGADSFENIWKKISQTLERKTDKESEETGSS
Protein: Ionotropic receptor 75d (Q9VVU7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Ionotropic receptor 21a
- IP13856p
- Ionotropic receptor 25a
- Ionotropic receptor 68a, isoform A
- Ionotropic receptor 93a
- Ionotropic receptor 41a
- Ionotropic receptor 76a, isoform E
- Ionotropic receptor 40a
- Ionotropic receptor 92a
- Ionotropic receptor 87a
Sequence:
MKVQVAHWLPLIFFLLVSGTPRVAGSWRSEYSRQDPDPKTRWGNQLPDMLVAYYRHHGVHSLMLVVCHTDIADFRLWKLWQHFNLNNFYVQVSTESSLRDLQHVDALDEHKDAPPPKSFHANNSTHWETSFLLPALPYKMGILLLEFSSECALNLLRWSAASEHNYFTTNRFWLLLTEDPGDIDLLEDPEIFIPPDSELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFTNIEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTVNYGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFAMPFENDVWVSILMLLIITTVVLVLELFFSPHNHDMSYMDTLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIGVQDTQYNKIYFTESTDPVTKNLYHKKIASKGENIYMRPLLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELEPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKCEGGVGGFVSIGITECRYALGIFGCGAAVSFVLFLFEFIFRHFKQVYRIIKGYREVQR
Protein: CUB-like domain-containing protein (Q9XUH3)
Organism: Caenorhabditis elegans
Interaction partners:
- CUB-like domain-containing protein
- CUB-like domain-containing protein
- CUB-like domain-containing protein
- ShKT domain-containing protein
Sequence:
MIRSTVLILASFALAVNCYECMNNTVVINAPSDISKPVFYPDGWDGQSSTPQISENQQCVMTINVPTGYYATVTFYKHFTEPGGYLYFPSRKIELLQNDDYNPYIFPSPMVKINIGTDNRNDVMNQFGFKVVYSKYPTLEKNIINIDLGSPPVAAKPSEKLTTFVGDRNSMMSLMGFTMADNSKNYLLRQTAIFGGDSTDSTYIGSLSQILNSQQILTTYGNKISVYTFGLDKLIDYPLFMGQNQVDTMGLLKYNGANCPSTGNCNVTLNGNWGAHVVVVTSYDGPETIKSFDSFPDTGVLNVYENNVSNTTCIATLNKFNYLQQLPLQVNGNMKFYELRAGGVYNMVVTRDTSRASRHQI
Protein: SR-CI (Q5ELT8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEFFWTLAVIVIYCIGHIHGRCERSIDLDNGSINYRQRNVVRFRCNRGYTLQGTVMQTCDRDGRLRGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGAYGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGTNGFTTTTEPTAPTGSNEQPLVYDMMSCSGRCGTSISASNITNNGIVMGCGCNDECLSDETCCLNYLEECTKELLTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTSTSTTTTKRPTTTTTTTKATTTKRTTTTKKPTTTSTTPKPTTTTSTTPMTTTSTTFTTSTTSTRPTTTTTINVFTTKKTTIMIPTSSTEKTTGINTTMKTLKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLGIVLVVVLANVVNRWIIPITGSKTSSEKAVRFKKAFDSLKKQRKRNSMDDQPLCDSDNDDVEYFEEMGVDIRHRTDL
Protein: Protein CCC1 (Cross-complementer of CSG1 protein 1) (P47818)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a role in both calcium and manganese homeostasis. Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:11390404, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:8866476}. Vacuole membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial RNA-splicing protein MRS4
- Mitochondrial RNA-splicing protein MRS3
- AP-1-like transcription factor YAP5
- Iron transporter SMF3
- Iron-regulated transcriptional activator AFT1
- Iron transport multicopper oxidase FET5
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
- Iron transporter FTH1
- Glutamate synthase
- Iron-sulfur assembly protein 1
Sequence:
MSIVALKNAVVTLIQKAKGSGGTSELGGSESTPLLRGSNSNSSRHDNLSSSSSDIIYGRNSAQDLENSPMSVGKDNRNGDNGSDNEKANLGFFQSVDPRVISDLIIGLSDGLTVPFALTAGLSSLGDAKLVITGGFAELISGAISMGLGGYLGAKSESDYYHAEVKKEKRKFYDNSNLINREIEDILLEINPNFSDETIVSFIKDLQRTPELMVDFIIRYGRGLDEPAENRELISAVTIGGGYLLGGLVPLVPYFFVSDVGTGLIYSIIVMVVTLFWFGYVKTKLSMGSGSSTSKKVTEGVEMVVVGGVAAGAAWFFVKLLG
Protein: Uncharacterized membrane protein YCR061W (P25639)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}. Note=Localizes to cytoplasmic punctate structures.
Interaction partners:
- Probable metabolite transport protein YBR241C
Sequence:
MVRFVSILSLFGCAATLVTAHDDMDMDMDMDMDMDMNIDTTTSQSIDVSSTASIVPVPHEPKHLHGLPILQSPSLTPAERLYWENYNTTTYFTTQAGNRSALRYHIITLLLVAFVLYPVSLALSAARSRWYLPLLFVNLCICISSVMALSVFKNTFPEEDWYAHNIYGTTSVLLLVFMLVHFFAAVLSVPVSLASKKEYRPVDTIPLNDLESTPVMVNSARGSPSPSSNRDTLFSLSSDTTTATATNNNKRRRAEGEDEGDNTSNHDTLRDEDYDNDDDEIASIEAPPLLPQDIPVFRILFTNTKYQMLAAHLSCVANVVFHMLTYPLFMYIFVDLIIGFAVGNLLGKGIRIFNLLAHWIKGGVFFTLGVVSLARYCGFAAKYGWAWNNISFTSQLTQTRSSNLLFRFAPAGTFTMEFVESFLIFFYGSTNIFLEHLAGNGGAWTAKDLQHVSIAFMFIGTGLCGLLTEYKLNHWRFEHARKRPQTDVVAATPGYSPNPFPAFTIFWTGILMSQHAQSSQFSTTIHTQWGYLLSYGSFFRLLTFLILFLVPNTNSAASKPFTELITSFCLLCGGLVFMESTDQSIEAMEYRGFTPMFTFNLSVGFVSLLMAWEMILFIWKDWLIKTRKTSL
Protein: Uroplakin 3b (Uroplakin-3b precursor) (A2CE76)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Tetraspanin
Sequence:
MNTHNAIRLVSLLSIWMLAAQGQIFQPQLAPANFLGRITSNTVILQQPYCVFTQTCPGCEIWLVAALSTGTGNFNALVNISSPISLSVSPYPTAFLPSSAQFFLTRVGPLANFPCNTAPAFPYFTVGADGICTGINCNGVLPVGSIVSFRYLLIDPSNYTVVNMTNWGGPFNLTTLLSYQTINDGLSARSGAMVVITTLLCVAVALLLLVFFIMLCVSCCGKKDGKTVTVMSSIRIPRYDTHNLKEHVHPYDNQAYEPDAKNYSRSQTLPKSPVRK
Protein: Transcription termination/antitermination protein NusA (N utilization substance protein A) (Transcription termination/antitermination L factor) (P0AFF6)
Organism: Escherichia coli (strain K12)
Function: Part of the processive rRNA transcription and antitermination complex (rrnTAC). The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP). It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis. Participates in both transcription termination and antitermination. Involved in a variety of cellular termination and antitermination processes, such as Rho-dependent transcriptional termination and intrinsic termination. Domain AR2 interacts with a large number of other proteins and may serve as a platform to recruit these factors for transcriptional regulation. Involved in phage lambda N-mediated transcriptional antitermination. Also important for coordinating the cellular responses to DNA damage by coupling the processes of nucleotide excision repair and translesion synthesis to transcription.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00945, ECO:0000269|PubMed:17272300}. Note=Colocalizes with nucleoids.
Interaction partners:
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit beta'
- DNA-directed RNA polymerase subunit alpha
- Transcription termination/antitermination protein NusG
- Translation initiation factor IF-2
- Small ribosomal subunit protein uS10
- Ribosome maturation factor RimP
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein uL11
- Small ribosomal subunit protein uS8
Sequence:
MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEIDVRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTFDRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEAVILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGEEVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLWDDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGWELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAARGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA
Protein: Nucleoside-diphosphatase uda-1 (EC 3.6.1.6) (Uridine-diphosphatase) (Q9XU84)
Organism: Caenorhabditis elegans
Function: Hydrolyzes UDP and GDP but not any other nucleoside di-, mono- or triphosphates. May promote reglycosylation reactions involved in glycoproteins folding and quality control in the endoplasmic reticulum.
Subcellular location: Endomembrane system {ECO:0000305|PubMed:15102851}; Single-pass type II membrane protein {ECO:0000305|PubMed:15102851}.
Interaction partners:
- Nucleoside-diphosphatase mig-23
- Probable GMP synthase
- Adenylosuccinate synthetase
- Ribonucleoside-diphosphate reductase large subunit
- Ribonucleoside-diphosphate reductase small chain
- UMP-CMP kinase 2
- UMP-CMP kinase 1
- Inosine triphosphate pyrophosphatase
- UDP-Glucose Glycoprotein glucosylTransferase
- Inosine-5'-monophosphate dehydrogenase
Sequence:
MLFPAFSILLISFFSLLSVVTTKTQYWCHGDGVLNNQHTCRFFTIVIDAGSTGTRLHLYKFIHDPAIASHGMPFKVEKEIFQEVKPGLSSFAKSPSSAADSLEPLLQRARKEVPHFMWEKTPITLKATAGLRLLPGDMADDILESVEERIFNSGFFAAFPDAVNVMPGSDEGVYSWFTLNILLETLFTDEPTVGHKPAAHRSVAAFDLGGGSTQLTYWPNNEAVFSEHVGYERDIDFFGHHIRLFTHSFLGNGLIAARLNILQLETDNEIESTHQLITSCMPEGYQLTEWEYALKFWNINGSSSHSFESCYGTTKNFVESSEIMHLRELKGSPVYLFSYFFDRALNSGLVKGNEGGKIELRQFKEAAEIACRREKTEIDDGSHWMPWQCLDLTYIYSLLRDGYQFEDNQPLVLAKKIKGMEVSWGQGLAFATANEFQLTEGAIKTALSSEPNSTVVDQIFDLVYSGTNQVLSYFNIISV
Protein: Viral interleukin-10 homolog (vIL-10) (20 kDa protein) (Protein BCRF1) (P03180)
Organism: Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Function: Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. Inhibits IFN-gamma synthesis.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MERRLVVTLQCLVLLYLAPECGGTDQCDNFPQMLRDLRDAFSRVKTFFQTKDEVDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPEAKDHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQIKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTIKAR
Protein: Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1) (Q12024)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}. Nucleus, nucleoplasm {ECO:0000305|PubMed:18448671}.
Interaction partners:
- Ribosome biogenesis protein 15
- ATP-dependent RNA helicase HAS1
- ATP-dependent rRNA helicase SPB4
- Ribosome biogenesis protein RPF2
- Ribosome biogenesis protein RLP7
- rRNA-processing protein EBP2
- Nucleolar complex protein 2
- Pescadillo homolog
- 25S rRNA
- Protein MAK16
Sequence:
MTEDKSQVKIRFFTREKDELLHVQDTPMYAPISLKRYGLSEIVNHLLGSEKPVPFDFLIEGELLRTSLHDYLTKKGLSSEASLNVEYTRAILPPSYLNSFSNEDWVSSLDVGDGSKHIISGSYDGIVRTWDLSGNVQKQYSGHSGPIRAVKYISNTRLVSAGNDRTLRLWKTKNDDLKLTSQQQAQEDDDDEVNIEDGKTLAILEGHKAPVVSIDVSDNSRILSASYDNSIGFWSTIYKEMTVVDPLEDINNPNNKISTAARKRRKLTMKDGTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTARCIDTRTTSYSLLSIAQLSTLNLLACGSSARHITLHDPRVGASSKVTQQQLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRSTSPMYTITREDKSVQKGVNDKVFAVKWAEKVGIISAGQDKKIQINKGDNIFKN
Protein: Surfactant protein C (SP-C) (Pulmonary surfactant-associated protein C) (Pulmonary surfactant-associated proteolipid SPL(Val)) (SP5) (P21841)
Organism: Mus musculus (Mouse)
Function: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
Subcellular location: Secreted, extracellular space, surface film.
Interaction partners:
- Pulmonary surfactant-associated protein B
- Pulmonary surfactant-associated protein A
- Uteroglobin
- Pulmonary surfactant-associated protein D
- Advanced glycosylation end product-specific receptor
- Secretoglobin family 3A member 2
- Napsin-A
- Aquaporin-5
- Adhesion G protein-coupled receptor F5
- Pro-cathepsin H
Sequence:
MDMSSKEVLMESPPDYSAGPRSQFRIPCCPVHLKRLLIVVVVVVLVVVVIVGALLMGLHMSQKHTEMVLEMSIGAPETQKRLAPSERADTIATFSIGSTGIVVYDYQRLLTAYKPAPGTYCYIMKMAPESIPSLEAFARKLQNFRAKPSTPTSKLGQEEGHDTGSESDSSGRDLAFLGLAVSTLCGELPLYYI