wanglab/gogpt-training-data huggingface dataset:
Protein: MICOS complex subunit mic19 (Q5ASP0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane (By similarity). Involved in osmoadaptation.
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
Interaction partners:
Sequence:
MGAGSSKPEASAGSKHIFESNSPIQFSSNLVDGLQSNTETDSARAKSLELEIQNRVAKELERLRAREQQTLAEIEKRLSEAKDTGSFASAPSAPAVTHYPAGSLDLDAPRIPFAGREYAPPPPAAVEVAAVNKELNRESVNSEIEELRVKLEGRKKLAELDEGVAKAQKDVVSCLRLNDRRPLDCWKEVAEFKKEVARLEEGFVDRIVG
Protein: Prokaryotic ubiquitin-like protein Pup (Bacterial ubiquitin-like modifier) (A0QZ48)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Among the identified substrates are the SodA and Ino1 proteins.
Interaction partners:
- Proteasome-associated ATPase
- Proteasome subunit beta
- Proteasome subunit alpha
- Pup deamidase/depupylase
- Pup--protein ligase
- Bacterial proteasome activator
Sequence:
MAQEQTKRGGGGGEDDDLPGASAAGQERREKLTEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
Protein: Aminopeptidase N (AnAPN1) (EC 3.4.11.2) (Alanyl aminopeptidase N) (Q7Q2T8)
Organism: Anopheles gambiae (African malaria mosquito)
Subcellular location: Cell membrane {ECO:0000255}; Lipid-anchor, GPI-anchor {ECO:0000255}.
Interaction partners:
- cystathionine gamma-lyase
- AGAP011158-PA
- Cysteine dioxygenase
- Cryptochrome-1
- AGAP008915-PA
- AGAP010241-PA
- AGAP000853-PA
Sequence:
MVRLLLLVSLGLCCLLASADRPPYKSSGIYEEEPQLPGASDLSGGVASDEIGVAPAQAVDERYRLPTTSIPIHYDLHLRTEIHRNERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKVSSLPNGVTGAPTLIGDVQYSTDTTFEHITFTSPTILQPGTYLLEVAFQGRLATNDDGFYVSSYVADNGERRYLATTQFESTSARMAFPCYDEPGLKATFTVSITHSLSYKAISNMPQKTTTDIETDMRTTFFEKTPAMSTYLLAFVVSDFQLRLSGAQRVYVRPNAFNEATFALEAGVKILKVLDDHLGIPYDTYMPKLDQIAIPDFAAGAMENWGLVTYREQALLFNPAVSTYRGKTNVATTIAHEYAHQWFGNLVSPEWWEYIWLNEGFATLYEFYALDMAYPGQEYWELFNQQVIQYAMGQDGQASTRPMNWNAATPGEISALFDRVAYDKSGSVLNMMRHVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGVLPNGVTVAQIMRTWTNEAGYPVLNVRRSYDTGDVIISQERFYNDRKVPNTNIWMIPYNYVHQAKADFNEFDDFQWLATKAARIETTVPANEWIVFNKQQVGYYRVNYDEHNWELITNALHENWASIHRLNRAQLIDDAYWLARSGRLDLRVALRFMTYLRNEREYAPWTAANVALTYFNNRLRGTAEYHNFLIFVDALIEDIYSLLTIDAVSPDDTLLHKYLVQTISTWACSMGYTDCLMKTAALLKAEASGTGPAVHPDIASVTYCYGMRSALESEFQYLYRKMMNSKNLAERTMLIDSLGCSNNKEFLKAFLTTALGSGTGVEINYRADERRRVVQAIYSGGRTGVDALIEFLMDPALVNEFVSTLSTSTLNSALSAIASRTNNVEEMNKLNALITALGSRVNSQTAANLRTTAQANLDWVNGFEGLMLSNFLAEFAAETLLTTTAAPETTTVTAGPTTTTTTPSSAVTTTTGPTSVTTTVVQTTTEEDDGAATIGLSIAALLVSITVHLLMG
Protein: Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1) (Q9ESM0)
Organism: Rattus norvegicus (Rat)
Function: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Inositol-pentakisphosphate 2-kinase
- Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
- Kinase
- Inositol hexakisphosphate kinase 2
Sequence:
MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTPEREQPRRKHSRRSLHRSGSGSDHKEEKASLSFETSESSQETKSPKVELHSHSDVPFQMLDSNSGLSSEKISYNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSASLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRSELRLKHVDMGLPEVPPLCGPSTSPSNTSLEAGPSSPPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ
Protein: VPS10 homolog 2 (Sortilin VTH2) (P40890)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Uncharacterized protein YJL027C
- Putative uncharacterized protein YJL009W
- Uncharacterized protein YJL028W
- Mitochondrial membrane protein FMP33
- Uncharacterized protein YJR056C
Sequence:
MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPISEKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSGLMYVGREIYTTNDGVSFSQVKPSFGKIDGHISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTGSTIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIPYRSNENGDVPSKFYYSLDQGKTWGEYDLIMPIYPYRLVSTISDGSGSKFILTGTSITEDPIFITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDKSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPDGFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTSRTDLLGASNIPDALPARSASHESDLAAARSEDK
Protein: Alpha-1,3-galactosyltransferase 2 (EC 2.4.1.87) (Isoglobotriaosylceramide synthase) (iGb3 synthase) (iGb3S) (A0A4Z3)
Organism: Rattus norvegicus (Rat)
Function: Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo-series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and is solely responsible for initiating the synthesis of isoglobo-series glycosphingolipids.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:17206613, ECO:0000269|PubMed:18630988}; Single-pass type II membrane protein {ECO:0000269|PubMed:17206613, ECO:0000269|PubMed:18630988}. Note=Also found in numerous large vesicles throughout the cytoplasm of the soma.
Interaction partners:
- UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
- Beta-galactosidase
- RNA helicase
Sequence:
MALEGLRAKKRLLWRLFLSAFGLLGLYHYWFKIFRLFEVFIPMGICPMAIMPLLKDNFTGVLRHWARPEVLTCTSWGAPIIWDETFDPHVAEREARRQNLTIGLTVFAVGRYLEKYLEHFLVSAEQYFMVGQNVVYYVFTDRPEAVPHVALGQGRLLRVKPVRREKRWQDVSMARMLTLHEALGGQLGREADYVFCLDVDQYFSGNFGPEVLADLVAQLHAWHFRWPRWMLPYERDKRSAAALSLSEGDFYYHAAVFGGSVAALLKLTAHCATGQQLDREHGIEARWHDESHLNKFFWLSKPTKLLSPEFCWAEEIGWRPEIHHPRLIWAPKEYALVRT
Protein: Adhesive plaque matrix protein (Foot protein 1) (MEFP1) (Polyphenolic adhesive protein) (Q25460)
Organism: Mytilus edulis (Blue mussel)
Function: Provides adhesiveness to the mussel's foot. Mussels produce one of the strongest water insoluble glues. The mussel's adhesive is a bundle of threads, called a byssus, formed by a fibrous collagenous core coated with adhesive proteins.
Subcellular location: Secreted.
Interaction partners:
Sequence:
TKHEPVYKPVKTSYSAPYKPPTYQPLKKKVDYRPTKSYPPTYGSKTNYLPLAKKLSSYKPIKTTYNAKTNYPPVYKPKMTYPPTYKPKPSYPPTYKSKPTYKPKITYPPTYKAKPSYPSSYKPKKTYPPTYKPKLTYPPTYKPKPSYPPTYKPKPSYPPSYKTKKTYPSSYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPTYKAKPTYPSTYKAKPSYPPTYKAKPTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPTYKAKPTYKAKPTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPTYKAKPTYPSTYKAKPSYPPTYKAKPSYPPTYKAKPTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPTYKAKPTYPSTYKAKPSYPPSYKAKPSYPPTYKAKPTYKAKPTYPSTYKAKPSYPASYKAKPSYPPTYKSKSSYPSSYKPKKTYPPTYKPKLTYKPTYKPKPSYPPSYKPKTTYPPTYKPKISYPPTYKAKPSYPATYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPSYKAKPTYPSTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPTYPSTYKAKPSYPPTYKPKISYPPTYKAKPSYPPTYKAKPSYPPTYKAKPTYKAKPTNPSTYKAKPSYPPTYKAKPSYPPTYKAKPSYPPTYKAKPTYKAKPTYPSTYKAKPTYKAKPTYPPTYKAKPSYPPTYKPKPSYPPTYKSKSIYPSSYKPKKTYPPTYKPKLTYPPTYKPKPSYPPSYKPKITYPSTYKLKPSYPPTYKSKTSYPPTYNKKISYPSSYKAKTSYPPAYKPTNRY
Protein: ADAMTS-like protein 3 (ADAMTSL-3) (Punctin-2) (P82987)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:14667842}.
Interaction partners:
- Mirror-image polydactyly gene 1 protein
- Protein hinderin
- Astrotactin-2
- Tyrosine-protein kinase FRK
- WD repeat-containing and planar cell polarity effector protein fritz homolog
- Transmembrane protein 212
Sequence:
MASWTSPWWVLIGMVFMHSPLPQTTAEKSPGAYFLPEFALSPQGSFLEDTTGEQFLTYRYDDQTSRNTRSDEDKDGNWDAWGDWSDCSRTCGGGASYSLRRCLTGRNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYNDVQYQGHYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISGICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSVRITVKGPAHLFIESKTLQGSKGEHSFNSPGVFLVENTTVEFQRGSERQTFKIPGPLMADFIFKTRYTAAKDSVVQFFFYQPISHQWRQTDFFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRWEHNPWTACSVSCGGGIQRRSFVCVEESMHGEILQVEEWKCMYAPKPKVMQTCNLFDCPKWIAMEWSQCTVTCGRGLRYRVVLCINHRGEHVGGCNPQLKLHIKEECVIPIPCYKPKEKSPVEAKLPWLKQAQELEETRIATEEPTFIPEPWSACSTTCGPGVQVREVKCRVLLTFTQTETELPEEECEGPKLPTERPCLLEACDESPASRELDIPLPEDSETTYDWEYAGFTPCTATCVGGHQEAIAVCLHIQTQQTVNDSLCDMVHRPPAMSQACNTEPCPPRWHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPEECRDEKPHALQACNQFDCPPGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKASSHKSCARTDCPPHLAVGDWSKCSVSCGVGIQRRKQVCQRLAAKGRRIPLSEMMCRDLPGLPLVRSCQMPECSKIKSEMKTKLGEQGPQILSVQRVYIQTREEKRINLTIGSRAYLLPNTSVIIKCPVRRFQKSLIQWEKDGRCLQNSKRLGITKSGSLKIHGLAAPDIGVYRCIAGSAQETVVLKLIGTDNRLIARPALREPMREYPGMDHSEANSLGVTWHKMRQMWNNKNDLYLDDDHISNQPFLRALLGHCSNSAGSTNSWELKNKQFEAAVKQGAYSMDTAQFDELIRNMSQLMETGEVSDDLASQLIYQLVAELAKAQPTHMQWRGIQEETPPAAQLRGETGSVSQSSHAKNSGKLTFKPKGPVLMRQSQPPSISFNKTINSRIGNTVYITKRTEVINILCDLITPSEATYTWTKDGTLLQPSVKIILDGTGKIQIQNPTRKEQGIYECSVANHLGSDVESSSVLYAEAPVILSVERNITKPEHNHLSVVVGGIVEAALGANVTIRCPVKGVPQPNITWLKRGGSLSGNVSLLFNGSLLLQNVSLENEGTYVCIATNALGKAVATSVLHLLERRWPESRIVFLQGHKKYILQATNTRTNSNDPTGEPPPQEPFWEPGNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKPLAGFEPCNIRDCPARWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGHPCVQWEPGNRCPGRCMGRAVRMQQRHTACQHNSSDSNCDDRKRPTLRRNCTSGACDVCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPISWRHCLGPSCDRDCTDTTHYCMFVKHLNLCSLDRYKQRCCQSCQEG
Protein: Stress-induced-phosphoprotein 1 (Hsc70/Hsp90-organizing protein) (G1TAF8)
Organism: Oryctolagus cuniculus (Rabbit)
Subcellular location: Dynein axonemal particle {ECO:0000256|ARBA:ARBA00024190}.
Interaction partners:
Sequence:
MEQVSELKEKGNQALSAGNIDDAVRCYSEAIRLDPRNHVLYSNRSAAYAKKGDYQKAYEDGCRTVELKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEASNPQLKEGLQNMEARLAERKVMNPFNMPHLYQKLESDPRTRALLSDPTYRELIEQLRHKPSDLGTKLQDPRIMTTLSVLLGVDLGSVDEEEEAAAAPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNEAYKKKDFDVALKHYDKAKELDPTNMTYITNQAAVYFEKGDYTRCRELCEKAIDVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR
Protein: Beta-klotho (BKL) (BetaKlotho) (Klotho beta-like protein) (Q99N32)
Organism: Mus musculus (Mouse)
Function: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
Interaction partners:
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor 1
- Fibroblast growth factor 15
- Fibroblast growth factor 21
- Fibroblast growth factor 23
- Fibroblast growth factor 4
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor 18
- Fibroblast growth factor 16
Sequence:
MKTGCAAGSPGNEWIFFSSDERNTRSRKTMSNRALQRSAVLSAFVLLRAVTGFSGDGKAIWDKKQYVSPVNPSQLFLYDTFPKNFSWGVGTGAFQVEGSWKTDGRGPSIWDRYVYSHLRGVNGTDRSTDSYIFLEKDLLALDFLGVSFYQFSISWPRLFPNGTVAAVNAQGLRYYRALLDSLVLRNIEPIVTLYHWDLPLTLQEEYGGWKNATMIDLFNDYATYCFQTFGDRVKYWITIHNPYLVAWHGFGTGMHAPGEKGNLTAVYTVGHNLIKAHSKVWHNYDKNFRPHQKGWLSITLGSHWIEPNRTDNMEDVINCQHSMSSVLGWFANPIHGDGDYPEFMKTGAMIPEFSEAEKEEVRGTADFFAFSFGPNNFRPSNTVVKMGQNVSLNLRQVLNWIKLEYDDPQILISENGWFTDSYIKTEDTTAIYMMKNFLNQVLQAIKFDEIRVFGYTAWTLLDGFEWQDAYTTRRGLFYVDFNSEQKERKPKSSAHYYKQIIQDNGFPLKESTPDMKGRFPCDFSWGVTESVLKPEFTVSSPQFTDPHLYVWNVTGNRLLYRVEGVRLKTRPSQCTDYVSIKKRVEMLAKMKVTHYQFALDWTSILPTGNLSKVNRQVLRYYRCVVSEGLKLGVFPMVTLYHPTHSHLGLPLPLLSSGGWLNMNTAKAFQDYAELCFRELGDLVKLWITINEPNRLSDMYNRTSNDTYRAAHNLMIAHAQVWHLYDRQYRPVQHGAVSLSLHCDWAEPANPFVDSHWKAAERFLQFEIAWFADPLFKTGDYPSVMKEYIASKNQRGLSSSVLPRFTAKESRLVKGTVDFYALNHFTTRFVIHKQLNTNRSVADRDVQFLQDITRLSSPSRLAVTPWGVRKLLAWIRRNYRDRDIYITANGIDDLALEDDQIRKYYLEKYVQEALKAYLIDKVKIKGYYAFKLTEEKSKPRFGFFTSDFRAKSSVQFYSKLISSSGLPAENRSPACGQPAEDTDCTICSFLVEKKPLIFFGCCFISTLAVLLSITVFHHQKRRKFQKARNLQNIPLKKGHSRVFS
Protein: Serine/threonine protein kinase (Q59VY9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MTLDILPIFDTHTKHHYVSSGATSTTDNTTTFTSATIYQPQTTTSSNKPNVNCLLNGYMLNHELRFIRKIGAGTYGLIYLVENIYTKQQFAAKMVLEQPLLKQKQQQQQSHHGHKGESSMNKQIISQEFYQYFLNNSMPQPRNLDLNYLRDNGHDCPFLTEISLHLKVHQHPNIATIHQVLNIEDFAIIILMDHFEQGDLFTNIIDRQIFTNNSHRKVPRTDFETQLLMKNAMLQLIEAIEYCHENNIYHCDLKPENIMVRYNPYYVRPTINNNNNNGEDDLCYANSIIDYNELHLVLIDFGLAMDSATICCNSCRGSSFYMAPERTTNYNTHRLINQLIDMNQYESIEINGTTVTKSNCKYLPTLAGDIWSLGVLFINITCSRNPWPIASFDNNQNNEVFKNYMLNNNKAVLSKILPISSQFNRLLDRIFKLNPNDRIDLPTLYKEVIRCDFFKDDHYYYAQHQHHHNHNQINNAYNHYQKQPNQARPTANQQLYTPPETTTYNSYASDMEEDEISDDEFYSDEEDEDIEEYEEEEEEYFGNEQQQQQQVTTVNGNFGQVKGTCYYDTKTKTTTYIKPPAAYTLETPSQSVEYC
Protein: Large ribosomal subunit protein eL38A (60S ribosomal protein L38-1) (Q9USR7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL37B
- Large ribosomal subunit protein eL8
Sequence:
MPRQISDIKQFLEIARRKDATSARIKKNTNKDVKFKLRCSKYLYTLVVADAKKAEKLRQSLPPDLTVTEVGKKA
Protein: Aldehyde dehydrogenase family 3 member I1, chloroplastic (AtALDH3) (Ath-ALDH3) (EC 1.2.1.3) (Q8W033)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long-chain saturated aldehydes are preferred substrates, while the short-chain aldehyde propanal is a weak substrate. Can use both NAD(+) and NADP(+), but the coenzyme preference is substrate dependent.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal
- Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial
- Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial
- Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial
- Aldehyde dehydrogenase family 7 member B4
- Aldehyde dehydrogenase family 2 member B4, mitochondrial
- Polyamine oxidase 3
- Polyamine oxidase 1
- Probable polyamine oxidase 4
- Polyamine oxidase 2
Sequence:
MTKLLEINHIQTLCFAKGFSPARLNVATSPFRISRRGGGGYCSNACIPYRLKFTCYATLSAVVKEQASDFSGKEAALLVDELRSNFNSGRTKSYEWRISQLQNIARMIDEKEKCITEALYQDLSKPELEAFLAEISNTKSSCMLAIKELKNWMAPETVKTSVTTFPSSAQIVSEPLGVVLVISAWNFPFLLSVEPVIGAIAAGNAVVLKPSEIAPAASSLLAKLFSEYLDNTTIRVIEGGVPETTALLDQKWDKIFFTGGARVARIIMAAAARNLTPVVLELGGKCPALVDSDVNLQVAARRIIAGKWACNSGQACIGVDYVITTKDFASKLIDALKTELETFFGQNALESKDLSRIVNSFHFKRLESMLKENGVANKIVHGGRITEDKLKISPTILLDVPEASSMMQEEIFGPLLPIITVQKIEDGFQVIRSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGVGESGIGAYHGKFSYETFSHKKGVLYRSFSGDADLRYPPYTPKKKMVLKALLSSNIFAAILAFFGFSKDS
Protein: 4-coumarate--CoA ligase CCL1 (HlCCL1) (EC 6.2.1.12) (M4ISH0)
Organism: Humulus lupulus (European hop)
Function: Involved in the biosynthesis of prenylated phenolics natural products which contribute to the bitter taste of beer and display broad biological activities (Probable). Catalyzes the ligation of CoA on (E)-4-coumarate to produce (E)-4-coumaroyl-CoA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:29760092}.
Interaction partners:
Sequence:
MENNKQDDHQEEFIFRSKLPDIYIPNHLPLHSYCFENISQFKDRPCLINGATGEIITYADVDLTSRKVAAGLDKLGIKQGDVIMLLLQNSPEFVYAFLAASYIGAIITTANPFYTPAEVAKQAAASKTKLVITLAGYIDKVKEFTGGESGVKVMCVDAPPPESECLHFSELTQADETEIPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHQNDVILCVLPLFHIYSLNSILLCGLRVGAAILIMQKFEISKLLELIEKFKVTIAPFVPPIVLSVAKCPDLHRYDLSSIRTVMSGGAPMGKELEDAVKEKLPHAKLGQGYGMTEAGPVLSMCLAFAKEPFPIKSGACGTVVRNAEMKIVDPDTGASLPRNQSGEICIRGKQIMKGYINDAEATKGTIDEGGWLHTGDIGFIDNDDELFIVDRLKELIKYKGFQVAPAELESMLISHPNITDAAVVPMKDEAAGEVPVAFVVRSNGSKITEEDIKQYISKQVVFYKRINKAFFIEEIPKNPSGKILRKILRAKLVTEQAI
Protein: procollagen-proline 4-dioxygenase (EC 1.14.11.2) (Q9VA52)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
Sequence:
MSSVVLFAVSFILVLSWIAEGYRDRQNYVISVEEKMDLLEKDRELIIVLDSYATELNEKIIMLKRIVKEFKQPLEKAKNREEEYLSNPIDSLSLMRQMHEDWEKVEKLLKKPVGQEKIALVEKMREDLPVENDLMEANQAMFRILHTYDLEPKDVSAGWIDGVQYGGKMSASDCFTMGTFSFMAGSYQIASKWLSAAKDLLVDQPRKYHEVMGITKADVTLLLARSLIASGNVSIATDMLMRDFMFGEAGSALTVHFLRNKPKPSINLESWESDESFNQLCRSSSRRQMGESKPSRLHCRYNTITTPFLKLAPFRMEELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAKVFRVEKGSDEIDPSRSADGAWLPHQNIDPDDLEVLNRIGRRIEDMTGLNTRSGSKMQFLKYGFGGHFVPHYDYFNSKTFSLETVGDRIATVLFYLNNVDHGGATVFPKLNLAVPTQKGSALFWHNIDRKSYDYDTRTFHGACPLISGTKLVMTRWIYELDQMFLIPAVLPPRSRNFSKSLPNPF
Protein: AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu 1 subunit) (Q6TLG2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
Sequence:
MSASAVFVLDLKGKVLICRNYKGDVDMSEIDHFFTLLMQQEEDGLISPVMSHGNVHFLWIKHNNLYLVATTNKNSNASLVYAFLYKLVEVFTEYFKELEEESIQDNFVVVYELLDELMDFGFPQTTDSKILQEYITQQGQKLEVAKTKVPTTVTNAVSWRSEGIRYKKNEVFIDVIESINVLVNANGSVMSSDIVGCIRLKTMLSGMPELRLGLNDRVLFALTGRDKGKTVVMEDVKFHQCVRLSRFESDRTISFIPPDGESELMSYRINTHVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVANNVEIRVPVPSDADSPKFKTSTGHAKYVPEKNLVVWSIKSFPGGKEFLMRAHFGLPSVENDELEGKPPITVKFEIPYFPVSGIQVRYMKIIEKSGYQALPWVRYITQSGDYQLRTNS
Protein: Integrator complex subunit 2 (Int2) (Q9H0H0)
Organism: Homo sapiens (Human)
Function: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:23904267, ECO:0000269|PubMed:39032490}. Nucleus membrane {ECO:0000269|PubMed:16239144}; Single-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:23904267}.
Interaction partners:
- Integrator complex subunit 1
- Integrator complex subunit 5
- Integrator complex subunit 3
- Integrator complex subunit 6
- Integrator complex subunit 8
- Integrator complex subunit 7
- Integrator complex subunit 11
- Integrator complex subunit 4
- Integrator complex subunit 9
- Integrator complex subunit 13
Sequence:
MKDQQTVIMTECTSLQFVSPFAFEAMQKVDVVCLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCKMNPSQALKVRGMVVEECHLPGLGVALTLDHTKNEACEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSSSVLWQMRRQLLLELMGILPTVRSTRIVEEADVDMEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNIFQGVIGGDNIRLNQRFSITAQLLVLYYILSYEEALLANTKTLAAMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTNNAKNHSPKQLQEAFSAVPVNNTQVMQIIEHLTLLSASELIPYAEVLTSNMSQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFVRQQKYTQNDLMIDPLIVLRCDQRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETEQDRPSQNNTIGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKANGVNPDSLLRNVQSVITTSAPNKGMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPIITRLQQIKEKPSGWSQICKDSSYKNGSRDTGSMDPDVQLCHCIERTVIEIINMSVSGI
Protein: Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (Haploid germ cell-specific nuclear protein kinase) (Q9Z0R0)
Organism: Mus musculus (Mouse)
Function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Subcellular location: Nucleus {ECO:0000269|PubMed:10358056}. Chromosome {ECO:0000250|UniProtKB:Q8TF76}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q8TF76}. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis. {ECO:0000250|UniProtKB:Q8TF76}.
Interaction partners:
- Aurora kinase B
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Inner centromere protein
- Sororin
- Borealin
- Shugoshin 1
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Kinesin-like protein KIF2C
- Cyclin-dependent kinase 1
- Shugoshin 2A
Sequence:
MAQAHPRSGTRLFRTYAARGVRGSQRQPGGLAEQWFQPPNLKRAFSSSLSDSNESPAVASDDPDDPDFPGSLVGQRRRRPRGSGSRNQRTLTNTPRVQRLRPRPPQKCSTPCSRLRPPPFPNCSPGCLGSDHSVCIQSRDSNELGTSASLFSSPASPGAPDPLYADSAVPGSFHLPAASLSEPSVPCPQVAATGDRYTGRALRAEASFRSSLFSLVNSGATEENKFGTDGENVKESCCERRQQMGNRLTDPDLTSPGKRKAACKKVVSQGVDQRDYEESSACKDLRVPGEISRPKRTGPLRKRKQQEATGTPPRHYHQSKKKRKASVSLWNLNTSQRDSWTKTRASFGFHKKKIITSVIEVCSSVASSSSRSLLSECSTPPIKNRAHLTVSSRCSSVYLLSPLKTLHVTDQRPSYAEKVYGECNQEGPIPFSDCLSTEKLERCEKIGEGVFGEVFQIINDQAPVALKIIAIEGLDLVNGSHQKTFEEILPEIIISKELSLLSSEAYNRTEGFIGLNSVHCVQGLYPPLLLKAWDHYNTTKRSANDRPDFFQEDQLFIILEFEFGGVDLERMKTKLSSVATAKSILHQITASLAVAEASLHFEHRDLHWGNVLLKKTNLKELRYTLNGKTSTIPTHGLQVNIIDYTLSRLERDGIVVFCDISAEEDLFTGEGDYQFEIYRLMRKENKNCWGEYHPYNNVLWLHYLTDKILNKMKFKTKCQSAAMKQIRKNLQHFHRTVLSFSSATDLLCQHSLFR