wanglab/gogpt-training-data huggingface dataset:
Protein: Putative O-antigen transporter (P37746)
Organism: Escherichia coli (strain K12)
Function: May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- dTDP-4-dehydrorhamnose 3,5-epimerase
- Putative O-antigen polymerase
- UDP-galactopyranose mutase
- Glucose-1-phosphate thymidylyltransferase 1
- dTDP-glucose 4,6-dehydratase 1
- Beta-1,6-galactofuranosyltransferase WbbI
- Putative glycosyltransferase WbbK
- dTDP-4-dehydrorhamnose reductase
- Putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ
- Probable ECA polymerase
Sequence:
MNTNKLSLRRNVIYLAVVQGSNYLLPLLTFPYLVRTLGPENFGIFGFCQATMLYMIMFVEYGFNLTATQSIAKAADSKDKVTSIFWAVIFSKIVLIVITLIFLTSMTLLVPEYNKHAVIIWSFVPALVGNLIYPIWLFQGKEKMKWLTLSSILSRLAIIPLTFIFVNTKSDIAIAGFIQSSANLVAGIIALAIVVHEGWIGKVTLSLHNVRRSLADGFHVFISTSAISLYSTGIVIILGFISGPTSVGNFNAANTIRNALQGLLNPITQAIYPRISSTLVLNRVKGVILIKKSLTCLSLIGGAFSLILLLGASILVKISIGPGYDNAVIVLMIISPLPFLISLSNVYGIQVMLTHNYKKEFSKILIAAGLLSLLLIFPLTTLFKEIGAAITLLATECLVTSLMLMFVRNNKLLVC
Protein: DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4) (Inhibitor of differentiation 4) (Q7ZXF3)
Organism: Xenopus laevis (African clawed frog)
Function: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Inhibits the activity of both neurogenic (neurog1/neurogenin, neurod1/neuroD) and myogenic (myod1/myoD) bHLH factors.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P47928, ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
Sequence:
MKAVSPVRPQSRKAQVPSVCGELALHCLSEHSLGVARYKMEEEETLCLQYDMNDCYSRLKRLVPTIPPNKKVSKVEILQHVIDYILDLQLALDTHPVLLRQQPPTRTPLTDLNTDPAALVVNKQGDSILCR
Protein: Putative phthiocerol dimycocerosate transporter LppX (Lipoprotein LppX) (P9WK65)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Might be involved in translocating phthiocerol dimycocerosates (PDIM) from the cell membrane to the outer membrane; PDIM forms part of the cell wall.
Subcellular location: Cell surface {ECO:0000269|PubMed:10678905}. Secreted, cell wall {ECO:0000269|PubMed:10678905}. Secreted {ECO:0000269|PubMed:10678905}. Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:10678905}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:24093492, ECO:0000305|PubMed:19661058}.
Interaction partners:
- Phthiocerol dimycocerosate exporter MmpL7
- Putative inactive phenolphthiocerol synthesis polyketide synthase type I Pks1
- Lipoprotein LpqH
- Phosphate-binding protein PstS 1
- Lipoprotein LpqN
- Phthiocerol/phthiodiolone dimycocerosyl transferase
- Probable doxorubicin resistance ABC transporter permease protein DrrC
- Uncharacterized PPE family protein PPE42
- p-hydroxybenzoic acid--AMP ligase FadD22
- Uncharacterized PPE family protein PPE13
Sequence:
MNDGKRAVTSAVLVVLGACLALWLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDATKGLTSVHVAVRTTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQGVPFRVQGDNISVKLFDDWSNLGSISELSTSRVLDPAAGVTQLLSGVTNLQAQGTEVIDGISTTKITGTIPASSVKMLDPGAKSARPATVWIAQDGSHHLVRASIDLGSGSIQLTQSKWNEPVNVD
Protein: Single-strand selective monofunctional uracil-DNA glycosylase (EC 3.2.2.-) (Q811Q1)
Organism: Rattus norvegicus (Rat)
Function: Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q53HV7}.
Interaction partners:
- G/T mismatch-specific thymine DNA glycosylase
- Uracil-DNA glycosylase
- Thymidylate synthase
- Methyl-CpG-binding domain protein 4
- Nei endonuclease VIII-like 1
- Uracil phosphoribosyltransferase homolog.
- DNA repair nuclease/redox regulator APEX1
- DNA polymerase lambda
- 5'-nucleotidase
- Methylcytosine dioxygenase TET
Sequence:
MAVSQTFPPGPAHEPASALMEPCARSLAEGFLEEELRLNAELSQLQFPEPVGVIYNPVDYAWEPHRNYVTRYCQGPKEVLFLGMNPGPFGMAQTGVPFGEVNVVRDWLGIGGSVLSPPQEHPKRPVLGLECPQSEVSGARFWGFFRTLCGQPQVFFRHCFVHNLCPLLFLAPSGRNLTPADLPAKHREQLLSICDAALCRQVQLLGVRLVVGVGRLAEQRARRALAGLTPEVQVEGLLHPSPRSPQANKGWETAARERLQELGLLPLLTDEGSVRPTP
Protein: Acetylornithine deacetylase, putative (EC 3.5.1.16) (Q581Z1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Arginase, putative
Sequence:
MNCREWLAKLVSYDTTSRNSNLELIYCIRSYLTALGVPSTLVYNDEKTKANLWATLAGEGGITDGGIILSGHTDVVPVDGQKWESDPFTLTERDGKFYGRGTCDMKGFIAVCMSLVPELLQMKRRKPIHLAWTYDEEVGCIGGQVLTQFLREQGVKAYGCIVGEPTSNQVVVAHKGIAVYRARVQGKAAHSSYALTRRSCNAIDYAAKLIVKIREIAEDFRCNGTCDSYFDVPNTTISTNLVTGGNAENTVPAVCEFVFEMRYLTNTDLGLIEKQIKTYAEGELLPLMKTEFDCASIEIVKMVGAPPLKQADEEDPFLILLRRIARDNAVRKVAYATEAGHYQGIGIPVGVCGPGSILQAHGANEFVTLEQLEGCAKIIREVAQDGDIGRKPHL
Protein: Nitroreductase domain-containing protein (Q57YA8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA-directed RNA polymerase subunit beta
- Transcription initiation protein, putative
- RNA polymerase-like protein
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Plastid-encoded RNA polymerase subunit alpha
- DNA-direcetd RNA polymerase II, subunit 9, putative
- DNA-directed RNA polymerase II, putative
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- Spt4/RpoE2 zinc finger domain-containing protein
- Telomerase-associated protein, putative
Sequence:
MRRSVYQLSKELPISEDEVACLVKKVMRECPSAFNSQSSRAVILFGEQHTKLWNLTKDKLKATVKPDSYNEAAKKIDGCFAPAAGTILFFEDKSVVEGLVKSYPAYAEGFPVWSTESSGMAQFAVWTALAEKGIGASLQHYTSLIGEAVTAEWKLPATWEMHAQMPFGKPLEKCGEKTYMPDEERFKVFK
Protein: Trafficking protein particle complex subunit 2/Sedlin, putative (Eurofung) (C8V2D4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- TMEM1 family protein, putative
- PutativeTRAPP
- Hypercellular protein A
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit BET3
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit 11 domain-containing protein
- Transport protein particle
- DUF974 domain protein
- GTP-binding protein ypt1
Sequence:
MSYYFTILSPTDVPLFNIAFGTSKSGGDGIARFRFPDAAQNTYMTQFIIHSSLDMLEEAQWMGGNMYLKHIDTYPPASAYVSAFLTPSGTRFLLLHQPPQPNLPPSGAGGGSGGLGSSTMSLGSSAMGMGGSGLFGGSGVGSSGRTSSSSIAANPTAPQTEEAVRQFMTEVYEAYVKTVMSPFYRRGMEIRSPVFRSKVSAAGRKWL
Protein: T3SS secreted effector NleA/EspI (Q8XAJ5)
Organism: Escherichia coli O157:H7
Interaction partners:
- T3SS secreted effector NleC
- Protein-arginine N-acetylglucosaminyltransferase NleB1
- Translocated intimin receptor Tir
- Serine protease EspP
- Secreted effector protein EspF
- T3SS secreted effector EspJ
- Effector protein NleF
- Adhesin
- EspA
- Cysteine S-methyltransferase NleE
Sequence:
MNIQPTIQSGITSQNNQHHQTEQIPSTQIPQSELPLGCQAGFVVNIPDDIQQHAPECGETTALLSLIKDKGLLSGLDEYIAPHLEEGSIGKKTLDMFGLFNVTQMALEIPSSVSGISGKYGVQLNIVKPDIHPTSGNYFLQIFPLHDEIGFNFKDLPGPLKNALSNSNISTTAVSTIASTGTSATTSTVTTEPKDPIPWFGLTAQVVRNHGVELPIVKTENGWKLVGETPLTPDGPKANYTEEWVIRPGEADFKYGASPLQATLGLEFGAHFKWDLDNPNTKYAVLTNAAANALGALGGFAVSRFASTDPMLSPHIGAMVGQAAGHAIQYNTPGLKPDTILWWAGATLGAADLNKAEFEVARFTDYPRIWWHAREGAIFPNKADIEHATGADIRAMEEGIPVGQRHPNPEDVVIDIESNGLPHHNPSNHVDIFDIIQETRV
Protein: Uncharacterized protein C16orf46 (Q6P387)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDLCQKNETDLENAENNEIQFTEETEPTYTCPDGKSEKNHVYCLLDVSDITLEQDEKAKEFIIGTGWEEAVQGWGRTSPAACIWPRKIPKKARVGEGACSDCLVCVNLSHWSLQTKPPTEGGPEKDQSSPSQTQAAPQGPSTASRAISDICFPTYFRAEKKSLQIKEFIWCNKDWAIPGTNRGKASGNPSGGAHRGLSIPGPLTSRALLVLPPLKASLSNALDVLGKKSKNSFLQSEEKVLDVEKDGCVAYAYGLKTADGKGEKRASELAKHPMVNDTPSSPSPAAQISLLTDPEQRCLHWSLLSEKNLACPPDPSNVRYLAALQLLQKRGVQSYKSKFKAKEPRSPVITRKHVLPKAKQENRPQMLETKVFPRPVLPSLTVSRVIIPVSTHRIL
Protein: Bacterial microcompartment shell protein EutL (BMC-T) (Ethanolamine utilization protein EutL) (P76541)
Organism: Escherichia coli (strain K12)
Function: A component of the bacterial microcompartment (BMC) shell dedicated to ethanolamine degradation (Probable). Two crystal forms have been seen; a form with a closed central pore that has 3 very small (1.1-2.2 Angstroms) channels per trimer lined by acidic and aromatic residues. A form with a large central pore (8-12 Angstroms) has also been seen; this is probably a functional pore which allows molecules to enter and exit the BMC in a selective, gated manner. Another group only sees the central pore in the presence of Zn(2+); soaking crystals in ZnCl(2) leads to dramatic conformational changes that open a central pore of about 12 Angstroms. Whether Zn(2+) binding is physiologically relevant is unclear, however it suggests a gating mechanism exists. Ethanolamine-binding by the small channels has been hypothesized to stabilize the EutL central pore in a closed (non-transporting) state. An open pore is thought to be large enough to transport ATP and/or cobalamin (By similarity).
Subcellular location: Bacterial microcompartment {ECO:0000305|PubMed:19451619, ECO:0000305|PubMed:20044574, ECO:0000305|PubMed:20851901}.
Interaction partners:
- Ethanolamine ammonia-lyase small subunit
- Bacterial microcompartment shell protein EutK
- Ethanolamine ammonia-lyase large subunit
- Bacterial microcompartment shell protein EutS
- Bacterial microcompartment shell vertex protein EutN
- Bacterial microcompartment shell protein EutM
- Acetate kinase EutQ
- Ethanolamine utilization protein EutJ
- Probable ethanolamine permease EutH
- Ethanolamine ammonia-lyase reactivase EutA
Sequence:
MPALDLIRPSVTAMRVIASVNADFARELKLPPHIRSLGLISADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMIAHIENGAAFQWANDAQDTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATYGIDAALKSADVQLATYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQRA
Protein: Histone-lysine N-methyltransferase KMT5B (Lysine N-methyltransferase 5B) (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361) (Q4FZB7)
Organism: Homo sapiens (Human)
Function: Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome integrity. In vitro also methylates unmodified 'Lys-20' (H4K20me0) of histone H4 and nucleosomes. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3. Facilitates TP53BP1 foci formation upon DNA damage and proficient non-homologous end-joining (NHEJ)-directed DNA repair by catalyzing the di- and trimethylation of 'Lys-20' of histone H4. May play a role in class switch reconbination by catalyzing the di- and trimethylation of 'Lys-20' of histone H4 (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:23720823}. Chromosome {ECO:0000250}. Note=Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity). {ECO:0000250}.
Interaction partners:
- DNA
- Histone H4
- Casein kinase II subunit alpha'
- N-lysine methyltransferase KMT5A
- Histone-lysine N-methyltransferase SUV39H1
- DNA
- Histone-lysine N-methyltransferase SETDB1
- Histone H4-like protein type G
- Calmodulin-lysine N-methyltransferase
- Chromobox protein homolog 1
Sequence:
MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA
Protein: LD43891p (Q7JVW9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSKAKKVLDEARETHNPELDLADKGLSSFEELPGLFNMSNITRLTLSHNKISVISPGIANLLNLEILNLSNNQLTELPVSLSSMPKLRILNVSINRLINLPRGFGAFPVLEVLDLSYNNLNEQVLPGNFFGMETLRALYLGDNDFEYIPKEVGQLKNLQILGLRDNDLLELPREVGDLVRLRELHIQNNRLQVLPPEIAQLDLLSNKSVMKMEENPWVNPIAEQYLLGISHVIDYLKTETYKIIYNRHLQAGRSGPPPPKADKSKKASRIRA
Protein: ADP-ribosylation factor-like protein 8d (AtARL8d) (ADP-ribosylation factor-like A1B) (AtARLA1B) (F4IZ82)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in lysosome motility. May play a role in chromosome segregation.
Subcellular location: Late endosome membrane {ECO:0000250|UniProtKB:Q9NVJ2}. Lysosome membrane {ECO:0000250|UniProtKB:Q9NVJ2}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9NVJ2}. Note=Localizes with microtubules at the spindle mid-zone during mitosis. {ECO:0000250|UniProtKB:Q9NVJ2}.
Interaction partners:
- Kinesin-like protein KIN-14E
- Protein TOM THREE HOMOLOG 1
Sequence:
MTLQPNLQAKEMELSLVGLQNSGKTSLVNVVATGEYSEDMIPTVGFNMRKVTKENVAIRLWDLGGQPRFRCMWERYCRAVSMIVYVVDAADTENLSVSRSELHDLLSNASLIGIPLLVLGNKIDIHGALSKEALTEEMGLSSVTSREVCCLMISCKNPTTIDQLTDWLVNHSKSKN
Protein: Probable ATP-dependent DNA helicase CHR719 (EC 3.6.4.12) (Protein CHROMATIN REMODELING 719) (OsCHR719) (Q60EX7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable chromatin-remodeling factor involved in root and shoot stem cell initiation, and root apical meristem (RAM) and shoot apical meristem (SAM) maintenance.
Subcellular location: Nucleus {ECO:0000269|PubMed:32808364}.
Interaction partners:
- Os04g0382100 protein
- Os02g0723700 protein
- Actin-related protein 4
- Os07g0609766 protein.
- Expressed protein
- SWI/SNF complex subunit SWI3A homolog
- Os02g0194000 protein
- SWI/SNF complex subunit SWI3C homolog
- Os12g0176700 protein
- Os09g0124200 protein
Sequence:
MAASVEAAAAAVVAPPASVGGDEVVVGGGGGGASEQARTLIGALNLLSRNLPLPPAVLHAVSSIYHGGDAWEGEGEEGGEEEVAAAAAAVGDGCGESGEGEEDRADASPGADEGVTLIQELEDAVLKNQGPYMSYSELTALKEDRFNTSIQHRLTELEGLPSTRGEDLQMKCLLELYGLKLLDLQKKVRTDISAEYWLHKKCAHPDRQLFDWGMMRIRYPFTMYGIGDSFSMDADDINRKKRFSERISRLEEEEKNQAEIRKRKFFSEILNAAREYQLQVPASYKRKKQRNDGVLAWHVRARQRINRMEKSRLQVLKAGDQEAYLRMVEESKNERLKLLLGKTNELLEGIGKAVQRQKDAEHVSRPDGSELPKGSESDDCSQISGLKVESPDEESPSDVDADHHSSADHSKFNAGHRLDSTVHSIEEKVTEQPSALEGGELRPYQLEGLQWMLSLFNNNLNGILADEMGLGKTIQTIALIAYLLEKKEVTGPHLIIAPKAVLPNWSNEFKTWAPSIGTILYDGRPDDRKALREKNFGQRQFNVLLTHYDLILKDLKFLKKVHWHYLIVDEGHRLKNHECALARTLVSRYQIRRRLLLTGTPIQNSLQELWSLLNFILPNIFNSSQNFEEWFNAPFACEVSLNDEEQLLIIHRLHQVLRPFLLRRKKDEVEKYLPVKTQVILKCDMSAWQKAYYEQVTSNGRVSLGSGLKSKALQNLSMQLRKCCNHPYLFVEHYNMYQRQEIVRSSGKFELLDRLLPKLQRAGHRVLLFSQMTKLLDILEVYLQMYQFKYMRLDGSTKTEERGRLLADFNKKDSEYFLFLLSTRAGGLGLNLQTADTVIIFDSDWNPQMDQQAEDRAHRIGQKNEVRVFVLVSVGSIEEEILDRAKQKMGIDAKVIQAGLFNTTSTAQDRRALLQEILRRGTSSLGTDIPSEREINRLAARNDEEFWLFEKMDEERRQRENYKPRLMEGIEVPDWVFANDTLTEKIPADEPQNVLLTTKRRRKEVVYSDSFGDQWMKADDVVEETPRMAPRAKRSAYSSDVQEVDFSERRKRHKSLVNIADDASIPMWTPEKVRAGVSSYSKDENEDDAEDESTTSVLQGGSFTWKTLRRKRSSHFSNSSDSKGRSAF
Protein: Octicosapeptide/Phox/Bem1p family protein (Q27GK5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- YTH domain-containing family protein
- Uncharacterized protein
- At1g67210
- Protein RECOGNITION OF PERONOSPORA PARASITICA 7
- DExH-box ATP-dependent RNA helicase DExH10
- Proline-rich spliceosome-associated
- DExH-box ATP-dependent RNA helicase DExH9
- Exosome complex component RRP41 homolog
- Transmembrane protein
- Zinc knuckle protein
Sequence:
MAAKSYLVIPTVNSVTTVVTLASSPFLAPSHFPVSFTLSISLSILNFTKKKTKSVLWKEKLRPHVWCVLTELASKMAEMCGGVGGSITVTIRCQLPTEDLDALVSITSDEDLVNLIEEYDLVSSSSPMKIRVFLNPPKSAAGSKKSPPPLALPSSTTTSSSSTTSSTSSSPRSPSLSKPPLPPSPPRITTVTKNPCYGCYVHRNSRNIYLVHNGNHWQ
Protein: Uncharacterized integrin beta-like protein C05D9.3 (Q9GYK2)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- FERM domain-containing protein
Sequence:
MKSRIFFITLLTIVAAQESADQLCSSFDAQQSCGQCIKAHAECAWCIDPHSSLTNRCQLKSKFTNETCTPHLVYSPQTAQVKIQQNLPLETKQHDGKTIVRQQPQAVSVRLMPSHSATVSFKYLHQTDPSRRSTEPETMEIQTSDVKDTPLQLKFFIVCDGELKETKSCRVQNNQIVEFKIEVLVNSCSSTGDITLSVGILRQRTIAGLYVTTICGCECEKHPEINSRLCHQNGHLVCGQCVCDQSRGGDKCECPLASHGVSKASELEDKCRFNSSSPVCSASGKCKCGQCQCNKPTVTGKFCQCDNDSCPLAVNGKVCSGNGVCDCGVCKCEMGWERDDCSCSTASNNCVDNGTPAPEEKDKPESVPEEPEATEKPDDMPSDSDLEKELDESSSAKEEQTSSSGVVSRVCVLLTFFLLVLNF
Protein: NAC domain-containing protein 78 (ANAC078) (Protein NTM1-like 11) (Q84K00)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). Transcripition activator associated with the induction of genes related to flavonoid biosynthesis and required for the accumulation of anthocyanins in response to high light stress. Plays a role in the regulation of 20S and 26S proteasomes in response to high light stress.
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q949N0}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353, ECO:0000269|PubMed:19887540}. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon specific stress or signal, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP). {ECO:0000250|UniProtKB:Q949N0}.
Interaction partners:
Sequence:
MGRGSVTSLAPGFRFHPTDEELVRYYLKRKVCNKPFKFDAISVTDIYKSEPWDLPDKSKLKSRDLEWYFFSMLDKKYSNGSKTNRATEKGYWKTTGKDREIRNGSRVVGMKKTLVYHKGRAPRGERTNWVMHEYRLSDEDLKKAGVPQEAYVLCRIFQKSGTGPKNGEQYGAPYLEEEWEEDGMTYVPAQDAFSEGLALNDDVYVDIDDIDEKPENLVVYDAVPILPNYCHGESSNNVESGNYSDSGNYIQPGNNVVDSGGYFEQPIETFEEDRKPIIREGSIQPCSLFPEEQIGCGVQDENVVNLESSNNNVFVADTCYSDIPIDHNYLPDEPFMDPNNNLPLNDGLYLETNDLSCAQQDDFNFEDYLSFFDDEGLTFDDSLLMGPEDFLPNQEALDQKPAPKELEKEVAGGKEAVEEKESGEGSSSKQDTDFKDFDSAPKYPFLKKTSHMLGAIPTPSSFASQFQTKDAMRLHAAQSSGSVHVTAGMMRISNMTLAADSGMGWSYDKNGNLNVVLSFGVVQQDDAMTASGSKTGITATRAMLVFMCLWVLLLSVSFKIVTMVSAR
Protein: Zinc finger protein WIP2 (Protein NO TRANSMITTING TRACT) (WIP-domain protein 2) (AtWIP2) (Q9SVY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization. May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique. Plays a role in replum development by the activation of the homeobox protein KNAT1.
Subcellular location: Nucleus {ECO:0000269|PubMed:20541552, ECO:0000269|PubMed:23515580, ECO:0000269|PubMed:25039392}.
Interaction partners:
- SUN domain-containing protein 1
- SUN domain-containing protein 2
- RAN GTPase-activating protein 1
- C2H2 and C2HC zinc fingers superfamily protein
- HAT family dimerization domain-containing protein
- Ac-like transposase
- C2H2-like zinc finger protein
- C2H2-like zinc finger protein
- Kinesin-like protein KIN-14C
- Kinesin-like protein KIN-1
Sequence:
MTDPYSNFFTDWFKSNPFHHYPNSSTNPSPHPLPPVTPPSSFFFFPQSGDLRRPPPPPTPPPSPPLREALPLLSLSPANKQQDHHHNHDHLIQEPPSTSMDVDYDHHHQDDHHNLDDDDHDVTVALHIGLPSPSAQEMASLLMMSSSSSSSRTTHHHEDMNHKKDLDHEYSHGAVGGGEDDDEDSVGGDGGCRISRLNKGQYWIPTPSQILIGPTQFSCPVCFKTFNRYNNMQMHMWGHGSQYRKGPESLRGTQPTGMLRLPCYCCAPGCRNNIDHPRAKPLKDFRTLQTHYKRKHGIKPFMCRKCGKAFAVRGDWRTHEKNCGKLWYCICGSDFKHKRSLKDHIKAFGNGHGAYGIDGFDEEDEPASEVEQLDNDHESMQSK
Protein: Cilia- and flagella-associated protein 144 (Testis highly expressed protein 6) (Q5NC57)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:27914912}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37295417}.
Interaction partners:
- Sperm acrosome-associated protein 9
- Cilia- and flagella-associated protein 45
- Tektin-1
- Dynein light chain roadblock-type 2
Sequence:
MAGRVGQMKNQDEVHQNQILRELFLKELRAQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLIHHAAQGPKKKYSETQTEAQEIGWDPNPLINPDRQDHRLNHFRVYHDITLYKAKLWSLGEDDHQK
Protein: Transcription factor kojR (Kojic acid biosynthesis cluster protein R) (Kojic acid biosynthesis cluster regulator) (Q2U5H9)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Transcription factor that regulates the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
Interaction partners:
- MFS-type transporter kojT
- Probable FAD-dependent monooxygenase kojA
Sequence:
MSLNTDDSGRIRTRQRAKRACETCKLRKRKCDGHEPCTYCLRYEYQCTFKPHPRRKPAASKSSARPSEEEDSPKFLDRVDANQEHMEANSGTAFPHLLGMRLNPQGAPKVYGFSWNLGPRDEPLEPFTNLTDLISREEMEDLASHYLKKIHPVYAVLDPDTLRQKIVARWHDPATAASYDPILCGVAALGSLYSGHQEHPKEGALVQSAKEMLETTRISKTTLLHHATAWILRTIYLRSTNCPHASWMASCSTMHIIEAIGAHQDPELVSLVYSDTADVSVNDESQRRLFWVATVLNSWISYEYGRSRVILRGVSCKPPLPRTGDFTTDLISMYQISERLDPDQNNKLSDLEDALSRVERLTLSHDALILSQSNLALTIYRRLRVASSNISNDILTRIIRLGNDGLEAAVRLAEDRSPWWHVANIPFQFLCILLAIDTRESLSYVGPALRSFRAITRHYSTPTLHTALETIESLVRLSQNKKERDLTLLRDSMQQEDPGLTEQGSTTSQAFNDASWLGATGDLTLPDNFDWDWNVFLDTQVPFFDEGEAGGQRYR
Protein: Lutropin-choriogonadotropic hormone receptor (Q6TCF8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU361222}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU361222}.
Interaction partners:
Sequence:
MWRSALLLVFLLLTSFCCGVCFECPEICRCSQKSITCNSATGSQKSLSRLVLNYISVKTISSRSFDGLKGVRRIEIAQSSSVETIESEAFNNLPNVSEISIQNTRNLVHIQQRAFNQLPKLRYLSISNTGISVFPDLTSIFSLEAHFILDICDNLNLRSVPSNAFTGMTSEYATMNLFNNGFQEIESHAFNGTKIDKLVLKNSRDLRVVHEDAFKGALGPTVLDVSSTALETLPSHGLESVLMLTARSAFALKKLPPLKSLKSLREAQLTFPSHCCALINWDNSRDGSVNSALRNRSSYCGDNSSPADLSAISSDDSLESDVIGSSSVEDTFGSIDFHYPDLDLCQQRQALQCSPEADAFNPCEDIAGFSFLRVAIWFINILAIAGNLVVLLVLFTSRCKLTVPRFLMCHLAFADLCIGIYLLMIATVDLRTRGHYSHHAIEWQTGAGCDIAGFLSVFGGELSIYTLSTITVERWHTITHALRLERRLGLSQASLIMTIGWLLCLAMALLPLIGVSSYSKVSMCLPMDIETPLSQAYVILLLLFNVGAFLVICGCYVCIYSAVRNPEFPGRAADAKIAKRMAVLIFTDFLCMAPISFFAISAAFKVPLITVTNSKILLVLFYPINSCANPFLYAIFTRAFRKDACILLSSMGCCQSKANLYRMKTYCSENINRSKSSSGSNANSKGPRAVMWMSSFPQLTPRPHIQRV
Protein: H-2 class II histocompatibility antigen, A-S beta chain (P06345)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MALQIPSLLLSAAVVVLMVLSSPGTEGGDSERHFVFQFKGECYFTNGTQRIRSVDRYIYNREEYLRFDSDVGEYRAVTELGRPDAEYYNKQYLEQTRAELDTVCRHNYEGVETHTSLRRLEQPNVVISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLISNGDWTFQVLVMLEMTPRRGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ