Protein: Transcription-associated protein 1 (Cel-trr-1) (TRRAP-like protein 1) (G5EEV2)
Organism: Caenorhabditis elegans
Function: Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development.
Subcellular location: Nucleus {ECO:0000269|PubMed:15068795}. Chromosome {ECO:0000269|PubMed:15068795}. Note=Localized to condensed chromosomes during pachytene and diakinesis stages of meiosis I in germ cells. {ECO:0000269|PubMed:15068795}.
Interaction partners:
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 10
- Histone acetyltransferase Tip60 homolog
- RuvB-like 1
- Enhancer of polycomb-like protein
- Uncharacterized protein
- histone acetyltransferase
- SANT domain-containing protein
Sequence:
MDPAMASPGYRSVQSDRSNHLTELETRIQNLADNSQRDDVKLKMLQEIWSTIENHFTLSSHEKVVERLILSFLQVFCNTSPQFIAENNTQQLRKLMLEIILRLSNVEAMKHHSKEIIKQMMRLITVENEENANLAIKIVTDQGRSTGKMQYCGEVSQIMVSFKTMVIDLTASGRAGDMFNIKEHKAPPSTSSDEQVITEYLKTCYYQQTVLLNGTEGKPPLKYNMIPSAHQSTKVLLEVPYLVIFFYQHFKTAIQTEALDFMRLGLDFLNVRVPDEDKLKTNQIITDDFVSAQSRFLSFVNIMAKIPAFMDLIMQNGPLLVSGTMQMLERCPADLISVRREVLMALKYFTSGEMKSKFFPMLPRLIAEEVVLGTGFTAIEHLRVFMYQMLADLLHHMRNSIDYEMITHVIFVFCRTLHDPNNSSQVQIMSARLLNSLAESLCKMDSHDTFQTRDLLIEILESHVAKLKTLAVYHMPILFQQYGTEIDYEYKSYERDAEKPGMNIPKDTIRGVPKRRIRRLSIDSVEELEFLASEPSTSEDADESGGDPNKLPPPTKEGKKTSPEAILTAMSTMTPPPLAIVEARNLVKYIMHTCKFVTGQLRIARPSQDMYHCSKERDLFERLLRYGVMCMDVFVLPTTRNQPQMHSSMRTKDEKDALESLANVFTTIDHAIFREIFEKYMDFLIERIYNRNYPLQLMVNTFLVRNEVPFFASTMLSFLMSRMKLLEVSNDKTMLYVKLFKIIFSAIGANGSGLHGDKMLTSYLPEILKQSTVLALTAREPLNYFLLLRALFRSIGGGAQDILYGKFLQLLPNLLQFLNKLTNLQSCQHRIQMRELFVELCLTVPVRLSSLLPYLPLLMDPLVCAMNGSPNIVTQGLRTLELCVDNLQPEYLLENMLPVRGALMQGLWRVVSKAPDTSSMTAAFRILGKFGGANRKLLNQPQILQVATLGDTVQSYINMEFSRMGLDGNHSIHLPLSELMRVVADQMRYPADMILNPSPAMIPSTHMKKWCMELSKAVLLAGLGSSGSPITPSANLPKIIKKLLEDFDPNNRTTEVYTCPRESDRELFVNALLAMAYGIWNKDGFRHVYSKFFIKVLRQFALIGVLEYIGGNGWMRHAEEEGVLPLCLDSSVMVDALIICLSETSSSFIIAGVMSLRHINETLSLTLPDIDQMSKVPMCKYLMEKVFKLCHGPAWYARSGGINAIGYMIESFPRKFVMDFVIDVVDSIMEVILGTVEEISSGSADSAYDCLKKMMRVYFIKEEGQEEENLTLATIFVSAISKHYFHSNERVREFAIGLMDHCMVHSRLAPSLDKFYYRFKEFFEPELMRVLTTVPTMSLADAGGSLDGVQNYMFNCPDGFDFEKDMDMYKRYLSHLLDIAQTDTFTLNQRNAFKKCETCPSHFLPPFPITTHIDSMRASALQCLVIAYDRMKKQYIDKGIELGDEHKMIEILALRSSKITVDQVYESDESWRRLMTVLLRAVTDRETPEIAEKLHPSLLKVSPISTIIIATFGASYIRNISGAGDDSDSDRHISYNDIMKFKCLVELNPKILVTKMAVNLANQMVKYKMSDKISRILSVPSSFTEEELDDFEAEKMKGIRELDMIGHTVKMLAGCPVTTFTEQIIVDISRFAAHFEYAYSQDVLVNWIDDVTVILNKSPKDVWKFFLSRESILDPARRSFIRRIIVYQSSGPLRQEFMDTPEYFEKLIDLDDEENKDEDERKIWDRDMFAFSIVDRISKSCPEWLISPNSPIPRIKKLFSETEFNERYVVRALTEVKKFQEEIIVKRMTEHKYKVPKLILNTFLRYLRLNIYDYDLFIVIASCFNGNFVTDLSFLREYLETEVIPKVPLQWRRELFLRIMQKFDTDPQTAGTSMQHVKALQYLVIPTLHWAFERYDTDEIVGTAPIDDSDSSMDVDPAGSSDNLVARLTSVIDSHRNYLSDGMVIVFYQLCTLFVQNASEHIHNNNCKKQGGRLRILMLFAWPCLTMYNHQDPTMRYTGFFFLANIIERFTINRKIVLQVFHQLMTTYQQDTRDQIRKAIDILTPALRTRMEDGHLQILSHVKKILIEECHNLQHVQHVFQMVVRNYRVYYHVRLELLTPLLNGVQRALVMPNSVLEKFSWQTRRHAVEICEMVIKWELFRTLKTDHIISDEEALEVDKQLDKLRTASSTDRFDFEEAHNKRDMPDAQRTIIKEHADVIVNMLVRFCMTFHQNSGSSSTSQSGNHGVELTKKCQLLLRAALRPSMWGEFVSFRLTMIEKFLSIPNDNALRNDISSTAYANTIQNAQHTLDMLCNIIPVMPKTSLMTMMRQLQRPLIQCLNNGAQNFKMTRLVTQIVSRLLEKTNVSVNGLDELEQLNQYISRFLHEHFGSLLNCRNLSGPVLGVLGAFSLLRTICGHEPAYLDHLMPSFVKVMERAAKEHLAYVANSQDGNMVKNFFPDVAELLCACMELVRPRVDHISMEIKRSIVGGIIAELIIKSNHDKIIQTSVKLLGAMISTQDMEFTILTVLPLLVRIQSIIVTKFKNCKDLIADYLVVVITVFENSEYRNSEAGSRLWEGFFWGLKSSDPQTREKFSIVWEKTWPHMATVDIAHRMKYIMQNQDWSKFKHAFWLKFALWGMLRTIAKRPTDPNNKRKKVILLNCATPWRTIEYAAKLKDQPMEVETEMKREEPEPMEVDEKDSQDDSKDAGEPKEKEKLTLELLLAGQQELLDEASNYDFADALDTVSQITFALNENQVTSKMWVVLFKSFWSSLSQSEIEDFTALVVPFMSSGVHNNYQTGVQDSVLAVWLEAVGDAVHLPSRLIEFISSKHECWHTGIRLLENHIWTIPKQLNNTLLREMKVAPGLAGDIETLESLGTLYNEISEFDQFAAIWERRAVFPDTMRAMSAMQLGDMELAQSYLEKSMSSTYETLAPTINPNNTSNSEKHVSPIIDKEYDHWMEMYITNCSELLQWQNVADVCNGKDMQHVRGLINAASHIPDWNVVEECKSQIAGCIPPSFHLDYTLFNLMSTVMRMNENSSPTHMKERCKIAIQECTEAHISRWRALPSVVSYGHVKILQAMNLVREIEESTDIRIALLEAPSNKVDQALMGDMKSLMKVFRNRTPTTSDDMGFVSTWYDWRNQIHGMMLQRFEYWDKVGLNVAATGNQSIVPIHSMAQAQLAVAKHAKNLGFHNLTKDLLNKLAGLTAIPMMDAQDKVCTYGKTLRDMANSAADERVKNELLCEALEVLEDVRIDDLQKDQVAALLYHRANIHSVLDQAENADYTFSAASQLVDLQNSVTTTGIKLMKNWGHHLYKRFFSTTVCKETGNNFGRQALACYFIAARVDNDIKARKPIAKILWLSKHLNACGSHEVMNRVIKKQLHSLNLFNWLYWLPQLVTDVRYKPNSNFVLILCKMAAAHPLQVFYHIREAVSVDDIDSVLEEDYTDEQMSMDVSDEDCFADDPPFDRILKICLKYRPTDIRVFHRVLKELDEMNETWVERHLRHAICLKDQMFKDFSEQMDATFNEMQYSEDVTMMTLRWRKQLEEDLVYFQQNYNLDFLEIRNKRKMIVTKGCMGVEKSQIMFEKELSQVFTEPAGMQDEFDFVTNMTNMMVSQLDIHAVDAPRPQGYIRIVLDWIRAIRRRFDRLPRRIPLESSSPYLARFSHRTGCIEMPYDLLNVLRAKNHTLMASNQTGQYISMLSRFEPNFEIVIKGGQVIRKIYIRGQTGKSAAFYLKKSVQDEPTNRVPQMFKHLDHVLQTDRESARRHLHAPTVLQMRVGQKTTLYEVASVQPYAMPPDCTRNYPASQIDIVHPYDVLTATFNGSYYPDDMVLHFFERFAQSSSSIGQPLPTPTNQDGTVAPPRLTEAHHIKNIIYEDFARDMIPFRLLYDYLTARYPDPVMYYAMKKQLLHSLAVLSTIEYHCNLTPMGPDQMMMTMNTGVLSNPSYRFEIRGGRSLHDIQHFGHEVPFRLTPNLSILVGVAQDGDLLWSMAAASKCLMKKEPEVIMRPLVWDEFANNTDCDKSRLQVFACHASNSYINGVASKLRNTNSADAKLRKDDCVSLISRAKDSDNLARMPPTYHAWF