wanglab/gogpt-training-data huggingface dataset:
Protein: Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) (P0CT40)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Meiotically up-regulated gene 106 protein
Sequence:
MSYANYRYMKARAKRWRPENLDGIQTSDEHLINLFAKILSKHVPEIGKFDPNKDVESYISKLDQHFTEYPSLFPNEHTKRQYTLNHLEELEQQFAERMFSENGSLTWQELLRQTGKVQGSNKGDRLTKTFEGFRNQLDKVQFIRKLMSKANVDDFHTRLFILWMLPYSLRKLKERNYWKSEISEIYDFLEDKRTASYGKTHKRFQLQNKNLGKESLSKKNNTTNSRNLRKTNVSRIEYSSNKFLNHTRKRYEMVLQAELPDFKCSIPCLIDTGAQANIITEETVRAHKLPTRPWSKSVIYGGVYPNKINRKTIKLNISLNGISIKTEFLVVKKFSHPAAISFTTLYDNNIEISSSKHTLSQMNKVSNIVKEPELPDIYKEFKDITAETNTEKLPKPIKGLEFEVELTQENYRLPIRNYPLPPGKMQAMNDEINQGLKSGIIRESKAINACPVMFVPKKEGTLRMVVDYKPLNKYVKPNIYPLPLIEQLLAKIQGSTIFTKLDLKSAYHLIRVRKGDEHKLAFRCPRGVFEYLVMPYGISTAPAHFQYFINTILGEAKESHVVCYMDDILIHSKSESEHVKHVKDVLQKLKNANLIINQAKCEFHQSQVKFIGYHISEKGFTPCQENIDKVLQWKQPKNRKELRQFLGSVNYLRKFIPKTSQLTHPLNNLLKKDVRWKWTPTQTQAIENIKQCLVSPPVLRHFDFSKKILLETDASDVAVGAVLSQKHDDDKYYPVGYYSAKMSKAQLNYSVSDKEMLAIIKSLKHWRHYLESTIEPFKILTDHRNLIGRITNESEPENKRLARWQLFLQDFNFEINYRPGSANHIADALSRIVDETEPIPKDSEDNSINFVNQISITDDFKNQVVTEYTNDTKLLNLLNNEDKRVEENIQLKDGLLINSKDQILLPNDTQLTRTIIKKYHEEGKLIHPGIELLTNIILRRFTWKGIRKQIQEYVQNCHTCQINKSRNHKPYGPLQPIPPSERPWESLSMDFITALPESSGYNALFVVVDRFSKMAILVPCTKSITAEQTARMFDQRVIAYFGNPKEIIADNDHIFTSQTWKDFAHKYNFVMKFSLPYRPQTDGQTERTNQTVEKLLRCVCSTHPNTWVDHISLVQQSYNNAIHSATQMTPFEIVHRYSPALSPLELPSFSDKTDENSQETIQVFQTVKEHLNTNNIKMKKYFDMKIQEIEEFQPGDLVMVKRTKTGFLHKSNKLAPSFAGPFYVLQKSGPNNYELDLPDSIKHMFSSTFHVSHLEKYRHNSELNYATIDESDIGTILHILEHKNREQVLYLNVKYISNLNPSTIMSGWTTLATALQADKAIVNDYIKNNNLNI
Protein: G protein-activated inward rectifier potassium channel 2 (GIRK-2) (BIR1) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (Potassium channel, inwardly rectifying subfamily J member 6) (P48550)
Organism: Rattus norvegicus (Rat)
Function: This potassium channel is controlled by G proteins. It may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium or cesium.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- G protein-activated inward rectifier potassium channel 3
- G protein-activated inward rectifier potassium channel 1
- Guanine nucleotide-binding protein G
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid type B receptor subunit 1
- Guanine nucleotide-binding protein G
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
Sequence:
MTMAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYVTSEILWGYRFTPVLTLEDGFYEVDYNSFHETHETSTPSLSAKELAELANRAELPLSWSVSSKLNQHAELETEEEEKNPEELTERNGDVANLENESKV
Protein: RAP domain-containing protein, chloroplastic (Protein ALBINO LEAF 1) (Q84MH1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable RNA-binding protein that plays an essential role in chloroplast development. Regulates the ribosomal proteins homeostasis and ribosomal RNA development in chloroplasts. Involved the regulation of 16S rRNA and required for the expression of chloroplast-associated photosynthetic genes.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:27208287}.
Interaction partners:
Sequence:
MEAALLRPPPLAARGGVSIAIAFSVSRLPSAAAAAAAGKPRKLAPPACRCRATPQWQLDFLGAEADTEADGGDDDDDLDLDLSLPAETNDWCVRARRSALRSIEARGLSPSLQRMVASPKKKNKKKKSKKTNLKQKKAAEPKPPRDTDDDEDDEEEADDDLEALLAGGGELDDLELRVAQFADGMFDEKRQRNREQFIQTLSAFSPAAPSNRSQEVSLNRSIVEARTADEVLALTAEVVAAVAKGLSPSPLTPLNIATALHRIAKNMEAVSMLQTHRLGFARSRDMSMLVGLAMVALPECSPQGVSNISWALSKIGGDLLYLPEMDRIAQVAITKVDSFNAQNVANVAGSFASMRHSAPDLISALTRRAAELVYTFKEQELAQFLWGCASLNECPYPLLDALDTACRDAPSFDCHLHDTVPGMWQSSDKEASSLKNSSNAYALNFTRDQIGNIAWSYAVLGQMDRPFFSGIWKTLSQFEERKISDQYREDMMFVSQVYLANQSLKLEYPHLDMCLRGDLEENLTKTGRSKRFNQKMTSSFQKEVGRLLCSTGHEWNKEYTIDGYTVDAVLVDEKLAFEIDGPSHFSRNLGTPLGHTAFKRRYIAAAGWNLVSLSHQEWENLEGEFEQLEYLRRILGFDAE
Protein: ORM1-like protein 2 (Adoplin-2) (Q53FV1)
Organism: Homo sapiens (Human)
Function: Negative regulator of sphingolipid synthesis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12093374}; Multi-pass membrane protein {ECO:0000269|PubMed:12093374}.
Interaction partners:
- Serine palmitoyltransferase 1
- Serine palmitoyltransferase 2
- Serine palmitoyltransferase 3
- Alpha-1-acid glycoprotein 1
- Serine palmitoyltransferase small subunit A
- Alpha-1-acid glycoprotein 2
- Serine palmitoyltransferase small subunit B
Sequence:
MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHMVLLSIPFFSIPVVWTLTNVIHNLATYVFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTASLLSVLLPKLPQFHGVRVFGINKY
Protein: Dynein intermediate chain, putative (Q385R8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}.
Interaction partners:
- Dynein heavy chain, putative
- Dynein heavy chain
- ODAD1 central coiled coil region domain-containing protein
Sequence:
MDTNARRASGGSAASVDAAPVAAAPPEDDRDAVIERILKATDPVVMSTPVYFDYRKDARTYRFFPSVGQTARHFSVDGGSVLKDDPEAIQQREDRQRREHDTELAARAELNPDLVDKGVSTSILKNQFNYSDRGSQTMNNAMVERCVLTDPPPSATFSAMATAWEIYDAYEEDRIQTEKSAAAVQKKTTSHRPTKEDKLSSTADESGGAKTAEEVLSSAAYKHSLKIIERMVNQNDCHDIIEDFKYWEDESDLYKEDGNLLPLWQFFTNKVKHRAVTSIALNNRYKDLFAVGFGSYDFQRQGKGAIHCFTLKNTVPTVPNSPLPAHPEMSFTVSSGVMCLSFHPVETSLLACGLYDGSVCVFDLRMHDKPKEEAKQICQATVRSGKHTEPVWEVQWCRSTVDLRFYSISTDGRITSWSLQKKELIFKDVMKTTTGACVFDPESLVLSRLSGTCFDFSNAYENLFIVGTQEGALMLCSKGYNGQCLERYEGHTMPVYTARWNPFHPDVFLTCSADWTVKLWLRSSTKPLLTFDAGDSVGDVAWAPYSSTVFSAVTSNGKVMVFDLNKNKREPLCSQTVVKNAKLTHVVFHKQDPVVLVGDSRGSVLILKLSPNLRTLCKPKKGEPEDPQHMRQMEVDKLNRLIDITLKDRILLGQA
Protein: Phenylserine dehydratase (EC 4.2.1.-) (Q10725)
Organism: Ralstonia pickettii (Burkholderia pickettii)
Interaction partners:
Sequence:
MTQLDTTTLPDLSAIAGLRARLKQWVRTTPVFDKTDFEPVPGTAVNFKLELLQASGTFKARGAFSNLLALDDDQRAAGVTCVSAGNHAVGVAYAAMRLGIPAKVVMIKTASPARVALCRQYGAEVVLAENGQTAFDTVHRIESEEGRFFVHPFNGYRTVLGTATLGHEWLEQAGALDAVIVPIGGGGLMAGVSTAVKLLAPQCQVIGVEPEGADAMHRSFETGGPVKMGSMQSIADSLMAPHTEQYSYELCRRNVDRLVKVSDDELRAAMRLLFDQLKLATEPACATATAALVGGLKAELAGKRVGVLLCGTNTDAATFARHLGLG
Protein: Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled) (Q8VHX2)
Organism: Mus musculus (Mouse)
Function: Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B (By similarity).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Tumor necrosis factor receptor superfamily member EDAR
- TNF receptor-associated factor 6
- Ectodysplasin-A
Sequence:
MASPDDPLRSDHMAKEPVEDTDPSTLSFAMSDKYPIQDTGLPKAKECDTVNSNCPPNSDDQPQGEENDFPDSTKDPLSGVSRNQPCKDRKGSCSCPSCSPRAPTISDLLNDQDLLDTIRIKLDPCHPTVKNWRNFASKWGMPYDELCFLEQRPQSPTLEFLFRNSQRTVGQLMELCRLYHRADVEKILRRWVDEEWPHRGHSDSSMHF
Protein: Protein MITOFERRINLIKE 1, chloroplastic (AtMFL1) (Q9FHX2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably involved in iron transport into chloroplasts.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000305|PubMed:21371898}; Multi-pass membrane protein {ECO:0000305|PubMed:21371898}.
Interaction partners:
- Solute carrier family 40 member 3, chloroplastic
- ABC transporter I family member 11, chloroplastic
- Protein TIC 21, chloroplastic
- Mitochondrial substrate carrier family protein
- Ferric reduction oxidase 7, chloroplastic
- Probable metal-nicotianamine transporter YSL4
- ADP,ATP carrier protein 1, mitochondrial
- CDGSH iron-sulfur domain-containing protein NEET
Sequence:
MEARLSETLGLPSPNLNHCHFPNEFNSLFTHFSDLTSVQSPIVRNPKLKTKSSQKPPKFSANFRRSDPPFASTSISDPTHEKPGPEFLKWIKPASRSSPRIQTLIKQLSVWERAIIGAGAGGLAGAFTYVTLLPLDAIKTKLQTKGASQVYSNTFDAIVKTFQAKGILGFYSGVSAVIVGSTFSSAVYFGTCEFGKSLLSKFPDFPTVLIPPTAGAMGNIISSAIMVPKELITQRMQAGASGRSYQVLLKILEKDGILGLYAGYSATLLRNLPAGVLSYSSFEYLKAAVLEKTKQSHLEPLQSVCCGALAGAISASITTPLDVVKTRLMTQIHVEAVDKLGGAMYTGVAGTVKQILTEEGWVGFTRGMGPRVVHSACFSAIGYFAFETARLTILNEYLKRKEESEANVAADS
Protein: LD21768p (Metallophosphoesterase, isoform A (EC 3.1.3.-)) (Q8T085)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MASLRVVNRLVCRGFVALTLLLVFFNEFIVYYMAQSSWQPIDCKLDNCTRLLLIADPQILGNSYDRSSHSPLARYDSDRYLAKTFERALAFTQPHIIVFLGDLLDEGNIATAQEYKQYVQRFRRIYQNKNYKKRVHVPGDNDIGGENGDYISNSNQRRFENEFMSEDLFDYDNRLRFFKINRMLLDFSNPDRDNNADRLRIGVSHAPLLIGGGPLLRAIISDLDPHIIFSGHWHESRIFIYPSTKVINFYENSVRHFDLKALKEQEHSYLEIMVPTCSYRMGKSKIGLGYAVLENYNLSYTVLWQPNRFILLFTYVFWGLFVVCGFVVFKMMTRCPFRVAKRQTLYNRVSTIPQF
Protein: U6 snRNA phosphodiesterase 1 (hUsb1) (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) (Mutated in poikiloderma with neutropenia protein 1) (Mutated in PN protein 1) (hMpn1) (Q9BQ65)
Organism: Homo sapiens (Human)
Function: 3'-5' RNA exonuclease that trims the 3' end of oligo(U) and oligo(A) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate. Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation. In addition also removes uridines from the 3' end of U6atac snRNA and possibly the vault RNA VTRNA1-1.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03040, ECO:0000269|PubMed:22899009, ECO:0000269|PubMed:23022480}.
Interaction partners:
- Pre-mRNA-processing factor 19
- ATP-dependent DNA helicase Q4
- SNW domain-containing protein 1
- Pleiotropic regulator 1
- Cell division cycle 5-like protein
- G patch domain-containing protein 1
- Pre-mRNA-splicing factor SYF1
- Peptidyl-prolyl cis-trans isomerase E
- Pre-mRNA-splicing factor ISY1 homolog
- Probable ATP-dependent RNA helicase DHX35
Sequence:
MSAAPLVGYSSSGSEDESEDGMRTRPGDGSHRRGQSPLPRQRFPVPDSVLNMFPGTEEGPEDDSTKHGGRVRTFPHERGNWATHVYVPYEAKEEFLDLLDVLLPHAQTYVPRLVRMKVFHLSLSQSVVLRHHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTSGHAQFLDLVSEVDRVMEEFNLTTFYQDPSFHLSLAWCVGDARLQLEGQCLQELQAIVDGFEDAEVLLRVHTEQVRCKSGNKFFSMPLK
Protein: Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] (Q91XD4)
Organism: Mus musculus (Mouse)
Function: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=More abundantly located around the mother centriole. {ECO:0000250}.
Interaction partners:
- Probable imidazolonepropionase
- C-1-tetrahydrofolate synthase, cytoplasmic
- Monofunctional C1-tetrahydrofolate synthase, mitochondrial
- Trifunctional purine biosynthetic protein adenosine-3
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial
- 5-formyltetrahydrofolate cyclo-ligase
- Serine hydroxymethyltransferase, mitochondrial
- Serine hydroxymethyltransferase, cytosolic
- Methionyl-tRNA formyltransferase, mitochondrial
Sequence:
MSQLVECVPNFSEGNNQEVIDAISRAISQTPGCVLLDVDAGPSTNRTVYTFVGQPECVVEGALHAARTASQLIDMSKHKGEHPRMGALDVCPFIPVRGVSMEECVLCAKAFGQRLAEELNVPVYLYGEAAQTPSRQTLPAIRAGEYEALPEKLKQAEWVPDFGPSSFVPSWGATVTGARKFLIAFNINLLSTKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLEEKNLAQVSTNLLDFEVTALHTVFEEARREAQELNLPVVGSQLVGLVPLKALLDAAAFYCDKEKLFVLEEEHRIRLVVNRLGLDSLAPFDPKERIIEYLVPDSGPEQSLLDTSLRGFVREVGARSAAPGGGSVAAAVAALGAALASMVGQMTYGRRQFDHLDSTMRRLIPPFHAASAQLTSLVDADARAFAACLEAIKLPKNTPEERDRRACALQEGLRQAVAVPLKLAETVSQLWPALQELAHCGNLSCLSDLQVAAKALETGVFGAYFNVLINLKDMTDDVFKEKTHHRISSLLQEAKTQAALVLGSLEARKE
Protein: A proliferation-inducing ligand-like protein (Tumor necrosis factor ligand superfamily member 13) (D2DMJ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MAEITQRFRPLDAAGNDGGKCRPDAVCYGVSCYHRFPDRAHRRVRDKRHVTEQKKQRKKRQKQHTFLHLVPVSSQSYNDDDSTVLSWAVGQSRGIGLQLSGDTVTVEAEGSYFIYSQVLYRDTTWVMGHVITKRQKGAESKLMKCLKSMPSNVSQPLNTCYSAGIYFLESGSTLQLSVPRRSAELILTAHATFMGLFSI
Protein: Defensin-like protein 1 (Low-molecular-weight cysteine-rich protein 68) (Protein LCR68) (Plant defensin 2.3) (Q9ZUL7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Confers broad-spectrum resistance to pathogens.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Defensin-like protein 18
- Defensin-like protein 19
- Defensin-like protein 14
- Defensin-like protein 249
- Defensin-like protein 13
- Defensin-like protein 16
- Precursor of CEP9
Sequence:
MKLSVRFISAALLLFMVFIATGMGPVTVEARTCESKSHRFKGPCVSTHNCANVCHNEGFGGGKCRGFRRRCYCTRHC
Protein: CG2264A (Q86MK1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MVARCVLFVTWLAVFIATGKSDDQLMKLPACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQCGGHQVSLKYSGSCNACLEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADDNKQFRRKGKLRCRANRRDRRRLASHQIGYNSDTSASKGSSEAGSTAHRTCSNSDRSQFNTNLMRMFRNEAQSFFRQPSLSDSHILEWQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVCFTKEFHNLLNSKPETASQDLENDSNCWMDQSVTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKRPQCDESVAVRPMKGCTEPRKTQFLKELKAYLNTSLLPSSTTGSNSSMWKTDDERIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLAEWLNCLQATPRESATTAKPAQSNETASPKFQGVNPVERYLKDAAA
Protein: Probable cyclic nucleotide-gated ion channel 10 (CaM-regulated potassium ion channel) (Cyclic nucleotide- and calmodulin-regulated ion channel 10) (Q9LNJ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable cyclic nucleotide-gated ion channel.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein ROOT HAIR DEFECTIVE 3 homolog 2
- Glutamate receptor 1.4
Sequence:
MAFSHDNRVRFKDEGKPLSSEYGYGRKARPSLDRVFKNVKWGFKKPLSFPSHKDPDHKETSSVTRKNIINPQDSFLQNWNKIFLFACVVALAIDPLFFYIPIVDSARHCLTLDSKLEIAASLLRTLIDAFYIIHIVFQFRTAYIAPSSRVFGRGELVDDAKAIALKYLSSYFIIDLLSILPLPQIVVLAVIPSVNQPVSLLTKDYLKFSIIAQYVPRILRMYPLYTEVTRTSGIVTETAWAGAAWNLSLYMLASHVFGALWYLISVEREDRCWQEACEKTKGCNMKFLYCENDRNVSNNFLTTSCPFLDPGDITNSTIFNFGIFTDALKSGVVESHDFWKKFFYCFWWGLRNLSALGQNLQTSKFVGEIIFAISICISGLVLFALLIGNMQKYLESTTVREEEMRVRKRDAEQWMSHRMLPEDLRKRIRRYEQYRWQETRGVEEETLLRNLPKDLRRDIKRHLCLDLLKKVPLFEIMDEQLLDAVCDRLRPVLYTENSYVIREGDPVGEMLFVMRGRLVSATTNGGRSGFFNAVNLKASDFCGEDLLPWALDPQSSSHFPISTRTVQALTEVEAFALTAEDLKSVASQFRRLHSKQLQHTFRFYSVQWRTWSVSFIQAAWRRYCRRKLAKSLRDEEDRLREALASQDKEHNAATVSSSLSLGGALYASRFASNALHNLRHNISNLPPRYTLPLLPQKPTEPDFTANHTTDP
Protein: ATP-binding cassette sub-family C member 6 (EC 7.6.2.-) (EC 7.6.2.3) (Multidrug resistance-associated protein 6) (Q9R1S7)
Organism: Mus musculus (Mouse)
Function: ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of glutathione conjugates such as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS) (in vitro), and an anionic cyclopentapeptide endothelin antagonist, BQ-123. May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (By similarity).
Subcellular location: Basolateral cell membrane {ECO:0000269|PubMed:15888484, ECO:0000269|PubMed:23625951}; Multi-pass membrane protein {ECO:0000255, ECO:0000269|PubMed:23625951}. Basal cell membrane {ECO:0000250|UniProtKB:O95255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Vitamin K-dependent gamma-carboxylase
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- Matrix Gla protein
- Prolactin-2C3
Sequence:
MNRGRSMATPGEQCAGLRVWNQTEQEPAAYHLLSLCFVRAASSWVPPMYLWVLGPIYLLYIHRHGRCYLRMSHLFKTKMVLGLALILLYTFNVAVPLWRIHQGVPQAPELLIHPTVWLTTMSFATFLIHMERRKGVRSSGVLFGYWLLCCILPGINTVQQASAGNFRQEPLHHLATYLCLSLVVAELVLSCLVDQPPFFSEDSQPLNPCPEAEASFPSKAMFWWASGLLWRGYKKLLGPKDLWSLGRENSSEELVSQLEREWRRSCNGLPGHKGHSSVGAPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDRNSSAWTGWLLAVLMFAAACLQTLFEQQHMYRAKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDIQRLAESIIYLNGLWLLFLWIFVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRGFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWEHAFLERLLHIRGQELSALKTSTLLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCIVQARVSFDRLAAFLCLEEVDPNGMIASNSRRSSKDRISVHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQKVLDACALGSDVASFPAGVHTPIGEQGMNLSGGQKQRLSLARAVYKKAAIYLLDDPLAALDAHVSQQVFKQVIGPSGLLQGTTRILVTHTLHVLPQADRILVLANGTIAEMGSYQDLLQRNGALVGLLDGARQPAGTHDAATSDDLGGFPGGGRPTCRPDRPRPTEAAPVKGRSTSEVQMEASLDDPEATGLTAEEDSVRYGRVKTTIYLSYLRAVGTPLCTYTLFLFLCQQVASFSQGYWLSLWADDPVVDGRQMHAALRGWVFGLLGCLQAIGLFASMAAVFLGGARASGLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDTVDVDIPDKLRSLLTYAFGLLEVGLAVTMATPLAIVAILPLMVLYAGFQSLYVATSCQLRRLESARYSSVCSHMAETFQGSLVVRAFRAQASFTAQHDALMDENQRVSFPKLVADRWLATNLELLGNGLVFVAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYARIPKEAPWRLPTCAAQPLWPCGGQIEFRDFGLRHRPELPLAVQGVSLKIHAGEKVGIVGRTGAGKSSLAWGLLRLQEAAEGNIWIDGVPITHVGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQEHTDEGIWAALETVQLKAFVTSLPGQLQYECAGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEMQMQAALERWFTQCTVLLIAHRLRSVMDCARVLVMDEGQVAESGSPAQLLAQKGLFYRLAHESGLA
Protein: Merozoite TRAP-like protein (Q8IJB7)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKKTILNLYLINILFALSDVKGISTHDTCDEWSEWSACTHGISTRKCLSDSSIKDETLVCTKCDKWGEWSECKDGRMHRKVLNCPFIKEEQECDVNNEMAEDTHMNNSYIYFNADDGDNEYEDHDDKNDDDKNYDNENDDDKNDDDKNDDDKNDDDKNDDDKNDDEENYNDTEEKVKNNDIHNSSANSNNEVTNFIQIKDKIMIKHKTTNIHPVNFIQEKYTRNNKYRSDNFSKILNNMNHINNNNYNSRSSSTSSKNARGYRGGSSNMYPHVPNYTSSSVHNSTNNERKSDEDLDNIEGDNITKEERIVPINNKNYDNHDEHSNIHEHDTSRNVDNEKYNSNDDLPNLSTYDYDMNNDSYKKNHMKKPMDSIKEEQTKQENNQNNEKVSSSEKQNDDISALYEHMNTKDQEHTQHEQPNDSAHGHFEDYSKLYIASGVATLVLLGGSITFYFLRKEKTEKVVQEETKEENFEVMFNDDALKGKDNKAMDEEEFWALE
Protein: FAD synthase (EC 2.7.7.2) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) (Q58579)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. To a lesser extent, is also able to utilize other nucleotides such as CTP and GTP as substrates, producing the modified coenzymes, flavin cytosine dinucleotide (FCD) and flavin guanine dinucleotide (FGD), respectively. Does not catalyze the reverse reaction to produce FMN and ATP from FAD and PPi. Does not function as a glycerol-3-phosphate cytidylyltransferase, as previously annotated in the complete genome.
Interaction partners:
- Riboflavin kinase
- Putative transport protein MJ1177
- Uncharacterized protein MJ0175
- Uncharacterized glycosyltransferase MJ1178
- 6,7-dimethyl-8-ribityllumazine synthase
Sequence:
MKKRVVTAGTFDILHPGHYEILKFAKSLGDELIVIVARDETVKKLKGRKPIIPEEQRREMVEALKPVDKAILGSLKNKLEPILELKPDIIVLGPDQTTFDEETLKKELAKYNLYPEIVRFRGYKKCPFHSSFDIVKEIIRRFCNKEIKI
Protein: Myosin light chain 1, skeletal muscle isoform (Alkali myosin light chain 1) (MLC-1) (Myosin light chain 1f) (Myosin light chain alkali 1) (Myosin light chain A1) (Skeletal-muscle myosin L-1 light chain) (P02604)
Organism: Gallus gallus (Chicken)
Interaction partners:
- Myosin heavy chain, skeletal muscle, adult
- Myosin regulatory light chain 11
- Troponin I, fast skeletal muscle
- Troponin I1, slow skeletal type.
- Troponin C, skeletal muscle
- Myosin-1B
- Actin, alpha cardiac muscle 1
- Troponin T, fast skeletal muscle isoforms
- Myosin regulatory light chain 2, smooth muscle major isoform
- EF-hand domain-containing protein
Sequence:
MAPKKDVKKPAAAAAPAPAPAPAPAPAPAKPKEPAIDLKSIKIEFSKEQQDDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVEELMKGQEDSNGCINYEAFVKHIMSV
Protein: Nuclear hormone receptor family member nhr-67 (Q9XVV3)
Organism: Caenorhabditis elegans
Function: Orphan nuclear receptor that binds DNA containing an extended core motif half-site sequence 5'-AAGTCA-3'. In males, plays an essential role in the migration of the linker cell which guides gonad elongation during the L3 and L4 stages of larval development by negatively regulating the expression of netrin receptor unc-5 at the mid-L3 stage. Involved in the regulation of non-apoptotic cell death in the linker cell, acting upstream of or in parallel to transcription factor hsf-1.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- Zinc finger protein egl-43
- Matrix metalloproteinase-A
- COG-1A
- Transcription factor fos-1
- Cyclin-dependent kinase inhibitor 1
Sequence:
MMTAVSQMSVPSSRILLDVDCRVCEDHSSGKHYSIFSCDGCAGFFKRSIRRHRQYVCKNKGSPSEGQCKVDKTHRNQCRACRLRKCLEIGMNKDAVQHERGPRNSSLRRQQMMFDHGSSPNSPEMGSESDAIILPTSSMNRDTVAGTAARIFFALVGFCQNPLNGVPKERQMTMFQQNWAALLVLHATETRAITSKQIRTETISGSSEQRNAVANAFEIIERLQLDNREYMMLKHFTMWRDTPSAIQIVFQLASIQNFTHRTEPTRYIQCINAIAAIPTTSIIDVLFRPSIGSASMPRLIQDMFKPPQQPTPTSLFPMANFNLNFLLKQEKTETEEGEDIEEEDDATSSNQFDENSSTDDRSVGELDPVQLFLALNSSTQPSSASSPSSSRPRHSIRSITELLSIQEEESVNVEEV
Protein: Myosin X,-like 1 (Unconventional myosin-X) (I3ITL5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
METFFAEGSRVWVNHKDQLLPSTVNSCGDGNLVLTTDYGEVVYLQQAEVNREKVSAMHQSSIDGVEDMSTLAELHEAAIMHNLHQRYQKDNIYTNIGSILAAVNPYKQIKGLYDLSAVELYSQHHLGELPPHIFAIANECYRCLWKRHDSQCVLISGESGAGKTESTKLLLQFLSVMSQNSAGTPPTEKSTRVEQAIVQSSPIMEAFGNAKTVYNNNSSRFGKFIQLHFSQSGNIQGGCIVDYLLEKNRVVRQNPGERNYHIFYALLAGASKSEKETYFLEDSPELFHYLSQSGCVKDRSLDDKKLFDDVMEALKVMEFTEEEIRDMFKLLSGVLQLGNVEFMTAGGAQITTKQVVTNVSELLGLDCFQLSEVLTQRSMILRGEEICSPLTVEQAIDSRDSVAMALYSQCFSWIIMRINQKIKGKDNFKSIGILDIFGFENFEVNRFEQFNINYANEKLQEYFNKHIFSLEQLEYNREGIHWEAIDWMDNAECLDLIEKKLGMLALVNEESRFPKGTDFTLLEKLHGRHSTNPYYVKPRLADHQFGIKHYAGEVLYDVRGILEKNRDTFRDDILNMLKDSRLDFIYDLFEQVSSRNNEETLKMGTARKKPTVSSQFRDSLHSLMATLSVSNPFFVRCIKPNMDKTPNKFDPEVVLNQLRYSGMLETVKIRRAGFPVRRTFKDFFTRYKIILKEKEKAAVASNGDDKKKSTDLLTIHDKTKKEWQFGKTKVFLKETLEQKLEKQRDEVRSKAGLIIRAYLLRYIARKDFKKALESIVTIQKNYRTHLYRRRFQRKRSAALVLQKHRRGQVARGVCRKLRDEKKKREEEERKKKEEQEKKTEGDREKKNEEEDEAESPRTVEEDTRQMEEILRLEREIEILQKKREDSVSTLCESSKQELRLRRDAEVLRQKKAASRVATEFLELLDTGGPEVIPGDPKQAASRSATATEEEVDEGFHAEEECIPLPEFPPPAEGPVDQEILATLPPPPAAFAEGTVAPSAPNVPPGAPPPPSPPPPPPLPGETKKEEGKPEEAKTDKEVDGKKEGEDVDRTSRLTAAESLPDTEEPIYSVPGDGESDYDQDDLEDGQSSIAATDGEHARKSTCTNASQESYNRSSDSYAESDDEHDGYVDTDEEVSNGKVNILNGNGPPYFHSYLYMKAGLMIPWRRRWCVLKDETFMWFRSKQESLKSGWLYKKGGGLSTLSRRNWKMRWFVLRDSKLMYFENDSEEKLKGTIDIRAAKEIVDNHEKENALNIVTDERTYQVFAESPEDASGWFTMLSRVHNASPEQLLEMSHEQANPKNAVGTLDVGLIDSVCASDNPDRPNSFVIITANRVIHCNSDLPEEMHHWISLLQKPKGDSKSDGQEFLVRGWLHKEMKAGAKSSALKLKKRWFVLTHNSLDYYKSSERNASKMGTLVLNSLCSVVQPEEKKFKETGYWNIIVHGRKHSYRLYTKLLNEAMRWVSAIQGVIDNKVPIETPTQQLIRDIKENSVNSEAVEQMYRRNPILRYTQHPLHSPLLPLPYGEVSDSLRKEKGYGSLQDEAVKIFNSLQEMEIVSDPVAIIQGILQTCHDLRPLRDEVYCQLIKQTNHVPQPNSPANRAHWHLLTCMSCTFLPSRAILRYLRFHLKRVRERYPGTEIEKYAHFIGESLKKTKAREYVPSQEEIAALLIRQEMTTTVYCHGGGSCKISINSHTTAGEVVEKLIRGLAMENSRNMFSLFEHNKVESRAIESRVIVADVLAKFERLTGSEEEEEEGPWRLYFKLYCFLDVESMPKEGVEFAFMFEQAHESLISGHFPAPEETLQHLAALRLQYIHGDVARTPWSLSSVYPVGRLRTRIFQSTKAGGAGVPGAGMVGPGGHTLERRKTNFLDGTLRRSFKTGSLKKQRVEEEHMLEMFVKEEMSATLTSVLEKWSRLQGMPQHQAMLNYMTVIKEWPGYGSTLFDVECKEGGFPHDLWLGVSAENVSVYKRGEPKPLETFQYEHIVFFGAPQPSTYKIIVDEREMFFETSQVGEITKIMKAYINMIVKKRCSIMSITSNSSAWMR