wanglab/gogpt-training-data huggingface dataset:
Protein: Collapsin response mediator protein 1 (E9PD68)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQKMNNEVVDKSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG
Protein: Zinc finger protein 748 (Q7TPL6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MEEMLSFRDVAVDFSAEEWECLEPAQWNLYRDVMLENYSHLVFLGLAFSKPYLVTFLEQRQEPLNEKRQVATTMHPDIKPYKCKECGKACDWNSLLLEHQRTNPGENAYKCEECGQASGSYSVIPEHHINDTEEKACKCEECGKVICTCSENSSYQRICIGENPYKCEECGKAFSSHSCLAQHEVEHTGQQFYNCEECGKLFYCPSHLTEHQKIHSQENLFKIEVCSEVFCAPIELSKDQNFCTEEKPYRYEDYVKAFSACSVLSEHPTIHPGEKAFKCEECGNAFCTLHSVSKMKIHYEVKSYKCEECGKAFATHLSLIQHKIGHTREKPYQCEECGKMFYCSSNLKQHQITHSQEKPYKCEVCGKVFRTCWQLSKHLRIHSGEKPYKCEECGKAFYTLSYLTQHKLGHTGEKPYKCEECGKTFYYPSVLKEHLAIHSGEKPYRCDECGKDFCTRSGRSRHQRIHTGEKPYKCEQCGKAFSTHSYLSHHKIVHTGHKPYKCEECGKKFYYPSRLKEHQRIHSQENPYKCEICGKAFYTHSYFTQHKLGHTGEKPYKCEECGKTFYYPSILKEHLAIHSGKKPYRCEECGKDFCTRSGRSRHQRIHTGEKPHKCEECGKVFSTHSYLTQHKVVHSGEKPYKCEECGKKFYYPSRLKEHQRIHSQENPYKCEICGNVFCTPKGLSKHQRFHTGEKPYKCEECGKMFYYPSRLKEHQRIHSQENPYKCEICGKAFYTHSYLTQHKLGHTGEKPYKCEECGKTFYYPSILKEHLAIHSGKKPYRCEECGKDFCTRSGRSRHQRIHTGEKPYKCEQCGKAFSTHSYLSQHKVVHSGEKPYKCEECGKMFYYSSRLKEHQRIHSQENPYKCEVCGKVFSAHLELATHLSIHSG
Protein: Peroxisomal membrane protein PEX14 (Peroxin-14) (Q8IEW2)
Organism: Trypanosoma brucei brucei
Subcellular location: Peroxisome membrane {ECO:0000256|ARBA:ARBA00046271, ECO:0000256|RuleBase:RU367032}.
Interaction partners:
Sequence:
MSLLLSGVVDDGKSKPEVEHTHSEREKRVSNAVEFLLDSRVRRTPTSSKVHFLKSKGLSAEEICEAFTKVGQPKTLNEIKRILSERPYVPTGPNSQHMTQPLRDESADSVPTPHPNQSRRHTSLLYAPQAPPLPEAAAATRGVDWRDLVIGAGAAVIGGFAAFKAFQLYSPYEIRLKDEGSKPRSRRSRRGGRHASSDSEAERSLVHREVPALPVPAIPVASESHVDAKQAEIERLKTELKETQEALEAEKKGKAELSITLGKLRGQVTAYSRTNEKQESQIKSLQEEVNRLKSEIERKEDSAKVNANSNVEETLDSKEEGLPSSDTESSNPNGASSEVARDTQQQDGPAPLSTETDGTVVGGEAA
Protein: Macrodontain-1 (EC 3.4.22.-) (Macrodontain I) (P83443)
Organism: Ananas macrodontes (False pineapple) (Pseudananas macrodontes)
Function: Cysteine protease that catalyzes the preferential cleavage: Ala-|-Xaa > Gln-|-Xaa > Tyr-Xaa >> Leu-|-Xaa > Gly-|-Xaa. Hydrolyzes the synthetic peptide substrate Bz-Phe-Val-Arg-pNA.
Interaction partners:
Sequence:
AVPQSIDWRDYGAVNEVKNQGPCGGCWAFAAIATVEGIYKIRKGNLVYLSEQEVLDCAVSYGCKGGWVNRAYDFIISNNGVTTDENYPYRAYQGTCNANYFPNSAYITGYSYVRRNDESHMMYAVSNQPIAALIDASGDNFQYYKGGVYSGPCGFSLNHAITIIGYGRDSYWIVRNSWGSSWGQGGYVRIRRDVSHSGGVCGIAMSPLFPTLQ
Protein: Uncharacterized protein KIAA1143 (Q96AT1)
Organism: Homo sapiens (Human)
Interaction partners:
- Transmembrane protein 204
Sequence:
MSKRNQVSYVRPAEPAFLARFKERVGYREGPTVETKRIQPQPPDEDGDHSDKEDEQPQVVVLKKGDLSVEEVMKIKAEIKAAKADEEPTPADGRIIYRKPVKHPSDEKYSGLTASSKKKKPNEDEVNQDSVKKNSQKQIKNSSLLSFDNEDENE
Protein: Pregnancy specific glycoprotein 18 (Q9R038)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MELSSELFSNGCTSWQRVLLTASLLTCWLLPTTARVTIESLPPQVYEGENVLLRVDNMPENLLVFGWYRGMTNLWQAIAQHWLYYYSVMVKGLNHSGREILYINGSLWIQNVTQEDTGYYTFQTISKRGEIVSNTSLYLHVYSSLFICVRPTTLISPTIELVPASVAAGGSILLLVHNIPKYLQSLFWYKGLIAFNKVEIARYRTAKNSGEPGPAHSGRETVYSNGSLLLQNVTWKDTGFYTLRTLTRYQKMEFTHIYLQLDTSHSLCCDTLDSAQLSIDPVPRHAAEGGSVLLQVHNLPEDVQTFSWYKGVLSTQDFKIAEYSIATKSIIRGRAHSRREIGYTNGSLLLQDVTEKDSGLYTLITIDSNVRVVTAHVQVNIHQLVTQPVMRVTDSTVRVQSSVVFTCFSDNTGISIRWLFNNQRLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPISLAVTNE
Protein: Interactor of constitutive active ROPs 2, chloroplastic (ROP-interactive partner 2) (Q9ZQC5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a scaffold, mediating interaction of ROPs with different proteins.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:18431481}.
Interaction partners:
- 50S ribosomal protein L11-like
- Large ribosomal subunit protein uL11y
- Large ribosomal subunit protein eL31x
- Large ribosomal subunit protein uL11z
- Large ribosomal subunit protein uL11x
- Large ribosomal subunit protein eL31y
- Large ribosomal subunit protein eL31z
- Ubiquitin-ribosomal protein eS31y fusion protein
- CRIB domain-containing protein RIC4
Sequence:
MQTPKPRPGSLEVPQKKSPASTPKTARKLKTSESDPVSSPNTKIRTPKTQSPKVVADRRSPRTPVNEIQKKRTGKTPELASQISQLQEELKKAKEQLSASEALKKEAQDQAEETKQQLMEINASEDSRIDELRKLSQERDKAWQSELEAMQRQHAMDSAALSSTMNEVQKLKAQLSESENVENLRMELNETLSLVEKLRGELFDAKEGEAQAHEIVSGTEKQLEIANLTLEMLRSDGMKMSEACNSLTTELEQSKSEVRSLEQLVRQLEEEDEARGNANGDSSSVEELKEEINVARQEISQLKSAVEVTERRYHEEYIQSTLQIRTAYEQVDEVKSGYAQREAELGEELKKTKAERDSLHERLMDKEAKLRILVDENEILNSKIKEKEEVYLNLENSLNQNEPEDTGELKKLESDVMELRANLMDKEMELQSVMSQYESLRSEMETMQSEKNKAIDEALAKLGSLTEEADKSGKRAENATEQLGAAQVTNTELEAELRRLKVQCDQWRKAAEAAATMLSGGNNNNNSNGKYVERTGSLESPLRRRNVNMSPYMGETDDELSSPKKKNGSMLKKIGVLLKKSQK
Protein: ZZ-type domain-containing protein (Q22436)
Organism: Caenorhabditis elegans
Interaction partners:
- Protein lgg-1
- Autophagy-related protein 11 C-terminal domain-containing protein
- Protein lgg-2
- Autophagy-related protein 18
- Protein sepa-1
- Beclin homolog
- Large ribosomal subunit protein eL43
- Helix-loop-helix protein 30
- Ectopic P granules protein 2
- Ubiquitin-like modifier-activating enzyme ATG7
Sequence:
MAAASSAPHQMQVRVTFYTSHNPQSVLMILKNDQALQQISEKARELFPSADYRLYYGDVNGPIFEFTNSDQIMSKIRITTFSRTPQLFVRLETVPLRPTALPSVSTETAKKASDADRESKSRSSLKRIENNQELTLKTLEKLQKELSRVSALETMVADLHAKEREPVVEEVQKPFPPVKHSASCDACLGDIIGHRFKCLECADYDLCEKCERKSLHYEHAMIRIVEPKKTMIPSYVTSNSPNNVFPTYMQHKIQQPQTIKGINKTVITRLVPSHQVNPAPMPQAPPVSTPVPFPPSPTIGNGAVPKPAQEPRIPPSPTSALPPPQFFNEETRAAIINSAALLKETFSTLSRSFLDLADGAQANMDKKIIERSTMEAGMTKFEEKMDNLKRHCEEKYLGTETAEAEKSEESSKKQADSLSGPKIKKAKKKSCYKKSAERLFTMQLAAAAAEQARLEQEAKKRAEASSAELQRKLAELNVKESQSKSEENIADFVLYDLYGNSLEALLRGRSSSRIADPPTTPNTEPATTELASTTSATPAVTAPASIVPVTPTAPIVETLIVPPLPPVESNPEEVTPMVTAPISIHSSFENISSDFESLSPSWGGYPDLEAAQRLEVIDDNLLDFSDVAVEAQEAQEAQEEARPEPEQSLPPFNEETEKTFDRLLEMGFSYNVTVAAIRANGSNLEMCLQALLH
Protein: Solute carrier family 2 member 1b (Solute carrier family 2, facilitated glucose transporter member 1) (F1R0Q1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Solute carrier family 2, facilitated glucose transporter member 5
- Facilitated glucose transporter 1
- Solute carrier family 2 member 2
Sequence:
MEGGKQLTLPLMLAVGTAVIGSLQFGYNTGVINAPQKIIEAFYNETWTARHGDMISKTTMTTLWSLSVAIFSVGGIVGSFSVGLFVNRFGRRNSMLMANVLAFIAAALMGFSKMAASWEMLIIGRFVVGLYSGLSTGFVPMYVGEVAPTALRGALGTLHQLGIVVGILMAQVFGMEAIMGNATMWPFLLGFTFIPALVQCCLLPICPESPRFLLINRNEESKAKSVLKKLRGTTDVSADMQEMKEESRQMMREKKVTIPELFRSPLYRQPIVIAIMLQLSQQLSGINAIFYYSTKIFEKAGVQQPVYATIGAGVVNTAFTVVSLFVVERAGRRSLHLLGLLGMAGSAILMTIAIALLEKYDWMSYMSIVAIFAFVAFFEIGPGPIPWFIVAELFSQGPRPSAFAVAGFSNWTANFIVGMCFQYVEEVCGAYVFVIFTVFLLCFFIFTYFKVPETKGRTFDEISAGFRQASGAEKHTPEELNSLGADSQL
Protein: Phenyloxazoline synthase MbtB (EC 6.3.2.-) (Mycobactin synthetase protein B) (P9WQ63)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the initial steps of the mycobactin biosynthetic pathway. Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores. Essential for growth in macrophages.
Interaction partners:
- Protein MbtH
- Salicyl-AMP ligase / salicyl-S-ArCP synthetase
- Polyketide synthetase MbtC
- Polyketide synthase Pks13
- Peptide synthetase MbtE
- Phthioceranic/hydroxyphthioceranic acid synthase
- Probable multifunctional mycocerosic acid synthase membrane-associated Mas
- Mycocerosic acid synthase-like polyketide synthase
- Mycoketide-CoA synthase
- Polyketide synthetase MbtD
Sequence:
MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR
Protein: Scm polycomb group protein like 2 (E9Q796)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGQTANEDHFDWDKYLKETGSISAPSEYFRQSKTPPTNEFKIGMKLEARDPRNIDSVCVASVIGITGARLRLRLDGSDNKNDFWRLVDSSDIQPVGTCEQGGDLLQPPLGYTLNTSSWPMFLLRVLTGSELAPAVFFKEEPPRPLQNNFIVGMKIEAVDRKNPFMICPATIGAVCGDQLHITFDGWSGAFDYWCDYDSRDIFPVGWCRLTGDVLQPPGKIVEKRPRRKRRTRLWRLRTALLGNEEEAPEAAEEPGTSVLTFGDENRTLKDCRGEAAEEPGTSAFTFGDENRTLKDCQGGWKKPKGRGFIKPGKDETRPGKHDQGAPAGKKPRGRGFTQPLEDEARPGRDVQVAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGAAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGAAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKPKGKRVTKSRKDQAQFLADEEAMPALSVSSTERTPPSSSEQPKSSTSGKTKSTSRGAQTSRKSPRKTSVVQPVPKTSKKAGKSKSTGNTSSPKKGITIKIVLPKKKGGKSGKKEKSIPVISSTSSASLSTLMKSSSSNKTSAGPSKIVMSTVCVYINKHGDCGPFLDPQKVQQLPNHFGPGPVNVILQRTVQACVNCAFQAKDVFLFLKTDNRGGEMITAFFDGKVHTVQLPPVNSASFALRFLENFCQSLQCDNFLSSQPFRREAQVPTPDTGTDQSKPENGEPKEKRSLKRLSLHPHRSAPVSSKVPRKSGQASKGN
Protein: Dual specificity phosphatase 16 (D4A3W6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase 12
- mitogen-activated protein kinase
- Mitogen-activated protein kinase 13
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 1
Sequence:
MAHEMTGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVGSLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANTGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLIHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFMGQLMDYEKTISSQTGMSGPKSKLKLLHLDKASEPVPAASEGGRKNALSLSPPCANSTSEAVGQRLVHPASVPSLQPSLLEDSPLVQALSGLQLSSEKLEDSNRLKRSFSLDIKSVSYSASVAASLHGFSSEDAMEYYKPSATLDGTSKLCQFSPVQEVSEQTPETSPDKEEAHIPRQPQATRPSESQTTRLHSVRTSSTGSTQRPFFSPLHRSGSVEDNYHTNFLFGLSTSQQHLTKSAAGLGLKGWHSDILPPQSSAPSLTSGWYFATEPSHFYSASAIYGGNASYSAYSCSQLPTCSDQIYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEVIEVS
Protein: Female-specific protein transformer (P11596)
Organism: Drosophila melanogaster (Fruit fly)
Function: Member of the regulatory pathway controlling female somatic sexual differentiation, regulated by Sxl. Activates dsx female-specific splicing by promoting the formation of a splicing enhancer complex which consists of tra, tra2 and sr proteins. Together with tra-2, plays a role in switching fru splicing from the male-specific pattern to the female-specific pattern through activation of the female-specific fru 5'-splice site. No known function in males.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:1655279}. Note=Speckled subnuclear compartment. {ECO:0000269|PubMed:1655279}.
Interaction partners:
- Protein sex-lethal
- Transformer-2 sex-determining protein
- Protein doublesex
- Sex determination protein fruitless
- RNA-binding protein 1
- E3 ubiquitin-protein ligase msl-2
- LD20987p
- LD40489p
Sequence:
MKMDADSSGTQHRDSRGSRSRSRREREYHGRSSERDSRKKEHKIPYFADEVREQDRLRRLRQRAHQSTRRTRSRSRSQSSIRESRHRRHRQRSRSRNRSRSRSSERKRRQRSRSRSSERRRRQRSPHRYNPPPKIINYYVQVPPQDFYGMSGMQQSFGYQRLPRPPPFPPAPYRYRQRPPFIGVPRFGYRNAGRPPY
Protein: Mitochondrial import inner membrane translocase subunit TIM50 (M0R2Q2)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU365079}; Single-pass membrane protein {ECO:0000256|RuleBase:RU365079}.
Interaction partners:
Sequence:
MAASAAVFSRLRSGLRLGSRGLCTRLATPPRRAPDQETTRWTKMVPRFLMSSTMMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGN
Protein: WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) (Q8IWA0)
Organism: Homo sapiens (Human)
Function: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:22916032, ECO:0000269|PubMed:34516797}.
Interaction partners:
- Small subunit processome component 20 homolog
- WD repeat-containing protein 36
- Transducin beta-like protein 3
- Ribosome biogenesis protein BMS1 homolog
- U3 small nucleolar RNA-interacting protein 2
- WD repeat-containing protein 3
- U3 small nucleolar RNA-associated protein 18 homolog
- Nucleolar protein 6
- WD repeat-containing protein 43
- U3 small nucleolar ribonucleoprotein protein MPP10
Sequence:
MVEEENIRVVRCGGSELNFRRAVFSADSKYIFCVSGDFVKVYSTVTEECVHILHGHRNLVTGIQLNPNNHLQLYSCSLDGTIKLWDYIDGILIKTFIVGCKLHALFTLAQAEDSVFVIVNKEKPDIFQLVSVKLPKSSSQEVEAKELSFVLDYINQSPKCIAFGNEGVYVAAVREFYLSVYFFKKKTTSRFTLSSSRNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDATEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDYGLIQIELTKAAFGCFGNWLATVEQRQEKETELELQMKLWMYNKKTQGFILNTKINMPHEDCITALCFCNAEKSEQPTLVTASKDGYFKVWILTDDSDIYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSVTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGATENGILCCWNLLSCALEWNAKLNVRVMEPDPNSENIAAISQSSVGSDLFVFKPSEPRPLYIQKGISREKVQWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFYFILGKHRQQQDEKLNETLENELVQLPLTENIPAISELLHTPAHVLPSAAFLCSMFVNSLLLSKETKSAKEIPEDVDMEEEKESEDSDEENDFTEKVQDTSNTGLGEDIIHQLSKSEEKELRKFRKIDYSWIAAL
Protein: Zinc finger protein 511 (Q8NB15)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transmembrane and coiled-coil domain-containing protein 6
- Abl interactor 2
Sequence:
MQLPPALCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKFKTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHRIPSTICFGQGAARGFKSNKKKTKQC
Protein: GTP-binding nuclear protein Ran (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) (P33519)
Organism: Dictyostelium discoideum (Social amoeba)
Function: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Exportin-T
- Uncharacterized protein
- Exportin-1
- Exportin-5
- Elongation factor 1-alpha
- Nuclear cap-binding protein subunit 1
- Nuclear cap-binding protein subunit 2
- 60S ribosomal export protein NMD3
- Nuclear transport factor 2
- Ran-specific GTPase-activating protein homolog
Sequence:
MAEKEQIKLVLVGDGGVGKTTFVQRHLTGEFEPRYIPTLGVSVHPLIFYTNFGKIHFNVWDTAGQEKFGGLRDGYYIQGNCAIIMFDVTSRISYKNVPNWHSDLTRVCENIPIVLCGNKVDVKDRKVKPSQIVFHRRYNLSYYDVSAKSNYNFEKPFVWLTSKLLGNKAVTLVQQPTLKLPETVLDSNLMSLYEKEVADAAALPLPEDNDDL
Protein: Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING finger protein 154) (RING-type E3 ubiquitin transferase DTX3) (Q8N9I9)
Organism: Homo sapiens (Human)
Function: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Protein mono-ADP-ribosyltransferase PARP9
- Neurogenic locus notch homolog protein 2
- Neurogenic locus notch homolog protein 4
- Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 3
Sequence:
MSFVLSRMAACGGTCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPEMHRAGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD
Protein: Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Negative regulator of URS2 protein 2) (Q06213)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 1
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 11
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 9
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 4
- Mediator of RNA polymerase II transcription subunit 20
Sequence:
MNGNSTNNEQLQQELATTQDQVASIIESFVELGVSIYDFPGTPEATKGMITNLQRNVDRLYKLNVRSNDPQSSLSKVDIPLEVVQYIEDGRNPDIYTREFVEAIRRSNQYQRGKMHGLKQLRDSLADKIVDEFPELKEPVEDIIKRTSPIDNVSNTH
Protein: Alpha/beta hydrolase fold-3 domain-containing protein (Q54K46)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MDPESFGLDKTAIEICNSYMPVLDIEPRLIREGFKSLYDIQKKHISKTKQYQLNKENGGSLMDVHFFYPNGYEQNPVDHKYKAIFYIHGGGFMVDGIKKLPREISDRTNSILIYPDYGLTPEFKYPLGLKQCYQLFTDIMNGNFNPFNDLINDSISIVGESSGGNFALSLPLMLKLNNSTFFKKISKVLVYYPITDCNFETPSYNRFSEKFYLTKEGMKWCWNHYTNNDSERDEITCCPLKATIDQLKDFPETLVITAETDVLSSEGEQFGLKLSNANVKVSVLRILKTIHGFVSLDQTNDSIACRVGMDLSMNFLNNISNSSIINENNNKTLLQLV
Protein: Glucose 1-dehydrogenase (GDH) (GlcDH) (EC 1.1.1.47) (Galactose 1-dehydrogenase) (EC 1.1.1.120, EC 1.1.1.48) (P13203)
Organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Function: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Is also significantly active with galactose as substrate, but not with mannose or glucose 6-phosphate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+). Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
Interaction partners:
- Aldose 1-epimerase
- Bifunctional protein FolD
- Aldose 1-epimerase
- Probable beta-galactosidase
- Glyceraldehyde-3-phosphate dehydrogenase
- Bifunctional phosphoglucose/phosphomannose isomerase
- Triosephosphate isomerase
- Probable 3-methyl-2-oxobutanoate dehydrogenase alpha chain
- Enolase
- Glucose kinase related protein
Sequence:
MTEQKAIVTDAPKGGVKYTTIDMPEPEHYDAKLSPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLRVDDARDNGYIKKGDLVVPLVRRPGKCINCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIEYLVKVEDPELGRIAVLTEPLKNVMKAFEVFDVVSKRSIFFGDDSTLIGKRMVIIGSGSEAFLYSFAGVDRGFDVTMVNRHDETENKLKIMDEFGVKFANYLKDMPEKIDLLVDTSGDPTTTFKFLRKVNNNGVVILFGTNGKAPGYPVDGEDIDYIVERNITIAGSVDAAKIHYVQALQSLSNWNRRHPDAMKSIITYEAKPSETNIFFQKPHGEIKTVIKWQ
Protein: Inactive alanine aminotransferase (Glutamate pyruvate transaminase) (GPT) (Glutamic--alanine transaminase) (Glutamic--pyruvic transaminase) (P52892)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Alanine aminotransferase, mitochondrial
- Alanine--glyoxylate aminotransferase 1
- Aspartate aminotransferase, mitochondrial
- Aspartate aminotransferase, cytoplasmic
- Arginine biosynthesis bifunctional protein ArgJ, mitochondrial
- Glutathione hydrolase proenzyme
- NAD-specific glutamate dehydrogenase
- NADP-specific glutamate dehydrogenase 2
- NADP-specific glutamate dehydrogenase 1
- Amino-acid acetyltransferase, mitochondrial
Sequence:
MTMTHQQDLKGVFTAKDLDFKPAGKITKKDLNTGVTKAEYAVRGAIPTRADELKEELKKNPEVLPFDDIINANIGNPQQLDQKPLTFTRQVLAILEYPEILRVGHNELASLNLFSRDALERAERLLNDIGGSIGAYSHSQGVPGIRQTVADFITRRDGGEPATPEDIYLTTGASSAATSLLSLLCKDSQTGLLIPIPQYPLYTASASLFNAQVLPYYLDEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKYGITIISDEVYQENIFNDVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSISKGFMDECGQRGGYMEIIGFSQEIRDALFKLMSISICSVVTGQAVVDLMVKPPQPGDESYEQDHDERLKIFHEMRTRANLLYETFKELEGIECQKPQGAMYLFPRLVLPKKALCESERLGIEPDEFYCTSLLESTGICTVPGSGFGQRPGTYHVRTTFLAPGTKWIQDWKEFHQDFFSKYRN
Protein: Potassium voltage-gated channel subfamily E member 1 (Q6FHJ6)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
Interaction partners:
Sequence:
MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP
Protein: Chaperone protein DNAJ, putative (Q584Q8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 50S ribosomal protein L17, putative
- Large ribosomal subunit protein uL15/eL18 domain-containing protein
- 50S ribosomal protein L13, putative
- Acyl carrier protein
- Large ribosomal subunit protein mL46
- 30S Ribosomal protein S17, putative
- Large ribosomal subunit protein uL3m
- Small ribosomal subunit protein mS29
- Ribosomal protein L11, putative
- 50S ribosomal protein L14, putative
Sequence:
MYVFRFHISSFHSFLVNFLQPSRGVGEPSRLLDHLETHPSYMRRVTSTAVHRTVSSVLSPALLPSFNGTLLLSVCFASCSAAPVRNLYKRLGLDHKATSEEVKAAYRQRALECHPDVVDDNRKAQAEVDFRAVSEAYDVLIDPQKRKEHDKALGLERTVPPAKKQQEGEGVGCDSKGSFNRGVTRPRNRKPFVRGDADRNFREAFHGMSLDQVLFRERLRQRRMQKQMEEKAKEGDDGSPAGREESIRRVAAAAAERFAEKVRRQYGPGMLRHARVYTSLSRDPQPPPSDYMPFRPFHGWTVPNGVRTPPEPTLGPTAKVEDVKDVQLAEPAVGDASHQRKLPKHFPVVQAPDGSSLLREEAIACMERERRLPHNMGKLYSYHRPY