wanglab/gogpt-training-data huggingface dataset:
Protein: Small ribosomal subunit protein uS12 (40S ribosomal protein S23) (Q6SA96)
Organism: Sus scrofa (Pig)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62266}. Cytoplasm {ECO:0000269|PubMed:24930395}. Rough endoplasmic reticulum {ECO:0000269|PubMed:24930395}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62266}. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (PubMed:24930395). {ECO:0000250|UniProtKB:P62266, ECO:0000269|PubMed:24930395}.
Interaction partners:
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS19
- 40S ribosomal protein S30
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein eS28
Sequence:
MGKCRGLRTARKLRSHRRDHKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS
Protein: Myelin protein zero-like protein 3 (Q6UWV2)
Organism: Homo sapiens (Human)
Function: Mediates homophilic cell-cell adhesion.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Flotillin-2
Sequence:
MQQRGAAGSRGCALFPLLGVLFFQGVYIVFSLEIRADAHVRGYVGEKIKLKCTFKSTSDVTDKLTIDWTYRPPSSSHTVSIFHYQSFQYPTTAGTFRDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKNPPDVHHNIPMTELTVTERGFGTMLSSVALLSILVFVPSAVVVALLLVRMGRKAAGLKKRSRSGYKKSSIEVSDDTDQEEEEACMARLCVRCAECLDSDYEETY
Protein: TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (R-esp1) (Protein GRG) (P63003)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- TLE family member 6, subcortical maternal complex member
- TLE family member 7
Sequence:
MMFPQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAHQLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSLSALGSQTHLSKEDKNGHDGDTHQEDDGEKSD
Protein: Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (D4A7D7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- RNA-binding protein 45
- Glucose-6-phosphate isomerase
- 6-phosphogluconolactonase
- Probable gluconokinase
- Glucose-6-phosphate 1-dehydrogenase
- Phosphoglucomutase-1
- Hexokinase-3
- Hexokinase-2
- N-acetylglucosamine-6-phosphate deacetylase
- Transaldolase
Sequence:
MKCTGIWKMLVAAVCLALLGCLQAQEFRGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKALESLSCPKDLVPSRCDELKAQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGVIRDTLQNHLTEILTLVAMELPPNISSSAAVLQHKLQAFQALRGLQKSNAILGQYQAYSGQVRQELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNRAYCTQGERHWVPERSRCLPQQIVFYIGHGELGHPAILVSKNLFKPSLPAQSWKGVQDQPGLHLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLSFEVPRLYPGGAENDHLLDFEFSGGQLTFSQQQLEVLMPELGSVPKPSDFQVLRAQYRKSPLITAWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPRGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG
Protein: Gli2 protein (Q8K0K3)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
RNAYSPRPPSINENVVMEAVAAGVDGPGLECDLGLVEDELVLPDDVVQYIKAHTGGTLDDGIRQGYPTEGTGFPENSKLPSPGLQGHRRLAAADSNMGPSAPGLGGCQLSYSPSSNLNKSNMPVQWNEVSSGTVDALPTQVKPPPFPHSNLAVVQQKPAFGQYPGYNPQSVQSSSGGLDSTQPHLQLRGAPSASRGSYTQQPRQPAAGSQCLGMSAAMSPQASYSQAHPQLSPNIVSGSLNQFSPSCSNMAAKPSHLGLPQQMEVVPNATIMNGHQREHGVPNSSLAAVSQPHPVLSYPQQDSYQQGSNLLSSHQPGFMESQQNAGFGLMQPRPPLEPNTASRHRGVRSGQQQLYARTTGQAMVTSANQETAEAMPKGPAGTMVSLAPQPSQDTGRAQDQNTLYYYGQIHMYEQNGGCPAVQPQPPQPQACSDSIQPEPLPSPGVNQVSSTVDSQLLEPPQIDFDAIMDDGDHSSLFSGALSPTLLHNLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
Protein: Epigen (Epithelial mitogen) (EPG) (Q924X1)
Organism: Mus musculus (Mouse)
Function: Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Epidermal growth factor receptor
- Probetacellulin
- Amphiregulin
- Proheparin-binding EGF-like growth factor
- Pro-epidermal growth factor
- Receptor tyrosine-protein kinase erbB-4
- Proepiregulin
- Receptor tyrosine-protein kinase erbB-3
- Protransforming growth factor alpha
Sequence:
MALGVLIAVCLLFKAMKAALSEEAEVIPPSTAQQSNWTFNNTEADYIEEPVALKFSHPCLEDHNSYCINGACAFHHELKQAICRCFTGYTGQRCEHLTLTSYAVDSYEKYIAIGIGVGLLISAFLAVFYCYIRKRCINLKSPYIICSGGSPL
Protein: Sodium/potassium/calcium exchanger 2 (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) (O54701)
Organism: Rattus norvegicus (Rat)
Function: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Required for learming and memory by regulating neuronal Ca(2+), which is essential for the development of synaptic plasticity (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:9461611}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDLHQSATVRLLQEWCSHESPSGCRRHYNTRKKLKLIRVIGLVMGLVAVSTVPFSISAFTETYSQNNRGEASDVTGPRAAPGHRQRTLLDLNDKIRDYTPQPPASQEDRSENGTDHAQGDYPKDVFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFAYVVFMKFNVQVERWVKQMINRNKVVKVTVSEAQAKASTAGDKEEPTLPNKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKKKCQVDENERQNGAANHVDYAAEKIELPNSTSTEVEMTPSSEASEPVQNGNLSHSIEAADAPQATETAEEDDDQPLSLSWPSNTRKQITFLIVLPIVFPLWITLPDVRKPASKKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTIIHRFKPVTVSSNGLFCAIVLLFIMLIFVILSIALCKWRMNKILGFIMFGLYFAFLVVSVLLEDKVLECPVSI
Protein: Histidine N-alpha-methyltransferase (EC 2.1.1.44) (Histidine trimethyltransferase) (P9WN47)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
Interaction partners:
- Hercynine oxygenase
- Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase
- Glutamate--cysteine ligase EgtA
- Probable hercynylcysteine sulfoxide lyase
- Histidinol dehydrogenase
- Uncharacterized protein Rv1480
- Possible conserved membrane protein
- Phosphoribosylamine--glycine ligase
- Citrate lyase subunit beta-like protein
- ATPase BagB
Sequence:
MRVSVANHLGEDAGHLALRRDVYSGLQKTPKSLPPKWFYDTVGSELFDQITRLPEYYPTRAEAEILRARSAEVASACRADTLVELGSGTSEKTRMLLDALRHRGSLRRFVPFDVDASVLSATATAIQREYSGVEINAVCGDFEEHLTEIPRGGRRLFVFLGSTIGNLTPGPRAQFLTALAGVMRPGDSLLLGTDLVKDAARLVRAYDDPGGVTAQFNRNVLAVINRELEADFDVDAFQHVARWNSAEERIEMWLRADGRQRVRVGALDLTVDFDAGEEMLTEVSCKFRPQAVGAELAAAGLHRIRWWTDEAGDFGLSLAAK
Protein: Large ribosomal subunit protein uL11m (39S ribosomal protein L11, mitochondrial) (L11mt) (MRP-L11) (Q9CQF0)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11279069}.
Interaction partners:
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL1m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL36m
- Large ribosomal subunit protein bL33m
Sequence:
MSKLSRATRTLKKPEAGGVIRSIVRAGQAIPGPPLGPILGQRGVSINQFCKEFNEKTKDIKEGIPLPTKIFIKPDRTFELKIGQPTVSYFLKAAAGIEKGARHTGKEVAGLVSLKHVYEIACVKAKDDAFAMQDVPLSSVVRSIIGSARSLGIRVVKDLSAEELEAFQKERAVFLAAQKEADLAAQAEAAKK
Protein: Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A) (O75164)
Organism: Homo sapiens (Human)
Function: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000269|PubMed:15927959, ECO:0000269|PubMed:16024779}.
Interaction partners:
- Histone H3.1
- Histone H3.1t
- Histone H3.3
- Histone H3.2
- Histone H3-7
- Histone H3.3C
- Histone H4
- Lysine-specific histone demethylase 1A FAD-dependent demethylase 1A)
- Histone H1.4
- Nuclear receptor corepressor 1
Sequence:
MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDLSSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTGVLTVHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAEVADEYMFSLEENKKSKGRRQPLSKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME
Protein: MAP kinase kinase kinase (EC 2.7.11.-) (C8VT14)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Cytoplasmic response regulator
- mitogen-activated protein kinase kinase
- Two-component system protein B
- Mitogen-activated protein kinase hog1
- RWD domain protein
- Histidine-containing phosphotransfer protein
- High osmolarity signaling protein sho1
- MAP kinase kinase
- Mitogen-activated protein kinase kinae mkk2
Sequence:
MDCCRHTVHRHSRLAAWRLDRLQLSPGFPIETTTKSWTLKRSANTSSWSNRTVGTPAFDKMSSPAVEGTPLVERELRMQQRPSHPARTPSNTYAPQRRPPPYISFQDDRQRSSSNKRTPRRNPDAQYRAQEKAYVQRIREDPQGWYSRFEDTGMGVTGDASDLEDPSPSSELPFEDDTYDPDIQLFIADDNQPSMEELKNPKNQERLEWHSMLASVLKGDVVKQEKQRLLGSAEPNRSAAQNHAIWLGVRARTCGRSLTLQRKLIEDARSGLGPIIENIINFEIKGETEIGKSPIKQVEDIVEQIGKCEALYPTHKELETAHPRVASEEYCSSRDAVFAWHNTTILINTELAILQKWVGNAELDFSKAGLKPANSDLSDESSFLDRIMKEDGLKTLQGEHNMLNGIGAVIQKAKNTLIENATSFAKRHLPPYIEELLILINFPSRLIQEIIRVRLSYARNMKDPAQQSPILVDQMITQFQILMRAAVDIKQRYLDIARPEPGWDLPPCIDESFDSVVLDALRYYFRLLNWKLQANKNTFKEAEILEQEWDFCNEIGRQLDSGDIEVAEQFSVLTARAIHRLLIHFERELHVQEDEDPAELDKRFKGILDSTRIRQRKLYRFSRFLRQLFENASEYNLPADISWDFFEALFVSDHFLIKSNASSAQKGVYYFAHPALWNRPDEIAAILGTSFREEEVGKELTHVPYVLAVRPEKPLSWAGKEMQVELVEQPTDLRLGKLRLIVEGSQQRLVNARLELTHLTGIQLDMAIEQRANLSRVNAELNRIKKISFKLSMTIMDSVAILRRQLREKGVENTELIQACYAFATEFGKRSSNVDPNRRAMNSARLAELSLDWVSFICDDCDAADRKTFKWAVAALEFAMAITSSRHLLSMDDAHFARLRQKVAGCMSLLISHFDIMGARSSRAAQAEKQRMDESARSWKIGAGRILTDEEAMRLVREQRLISLNAIEEGRVEADAKRQALGRVLEGTNEADKSLAVLSSSATNVTLRWQQGQYIGGGTFGSVYAAINLDSNYLMAVKEIRLQDPQLIPKISQQIRDEMGVLEVLDHPNIVSYHGIEVHRDKVYIFMEYCSGGSLATLLEHGRVEDETVIMVYALQLLEGLAYLHQSGIVHRDIKPENILLDHNGIIKYVDFGAAKIIAHNQVAPNRGKNQKTMTGTPMYMSPEVIRGDTSKLVHRQGAVDIWSLGCVILEMATGRRPWSSLDNEWAIMYNIAQGNQPALPSRDQLSDLGLDFLRRCFECDPMKRPTAAELLQHEWIVSIRQQVVIETPTPSSEHSGSISSSNSGSRHSSAYM
Protein: Transmembrane protein (F4ILY0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGTRQVYEEKLRRGNLDYDPTMNPGLGSARCPRCLSLLNPNSEKGEWTITPVLHDAAAVAGSGIGGLLSAVHAFNTGIPYLQNRFSGSKRLSFLVGVPLLLVYSGVGAAFGESLQAAISFPIVWLEYESRCAAQCRIATFTFSLLFDVPGYALPKFAQLTVTSYYASSSASHYGISMLTRRIEEAHLSRTQKEEAEFAPFGPSP
Protein: Cytochrome P450 97B3, chloroplastic (EC 1.14.-.-) (O23365)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Heme-containing cytochrome P450 probably involved in the biosynthesis of xanthophylls. Hydroxylates beta-rings of alpha-carotene. May also have activity on beta-rings of beta-carotene.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:18431481}.
Interaction partners:
- NADPH--cytochrome P450 reductase 1
- NADPH--cytochrome P450 reductase 2
- Beta-carotene 3-hydroxylase 1, chloroplastic
- Beta-carotene 3-hydroxylase 2, chloroplastic
- NADPH-dependent diflavin oxidoreductase 1
Sequence:
MVAAMAFPAAATYPTHFQGGALHLGRTDHCLFGFYPQTISSVNSRRASVSIKCQSTEPKTNGNILDNASNLLTNFLSGGSLGSMPTAEGSVSDLFGKPLFLSLYDWFLEHGGIYKLAFGPKAFVVISDPIIARHVLRENAFSYDKGVLAEILEPIMGKGLIPADLDTWKLRRRAITPAFHKLYLEAMVKVFSDCSEKMILKSEKLIREKETSSGEDTIELDLEAEFSSLALDIIGLSVFNYDFGSVTKESPVIKAVYGTLFEAEHRSTFYFPYWNFPPARWIVPRQRKFQSDLKIINDCLDGLIQNAKETRQETDVEKLQERDYTNLKDASLLRFLVDMRGVDIDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLGQGPPTYESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFWDNPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVELRGTPESVELVSGATIHAKNGMWCKLKRRSK
Protein: Purple acid phosphatase 10 (EC 3.1.3.2) (Q9SIV9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: [Isoform 1]: Secreted {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000305}.
Interaction partners:
- Pectin lyase-like superfamily protein
- SPX domain-containing protein 2
- Protein PHR1-LIKE 2
Sequence:
MGRVRKSDFGSIVLVLCCVLNSLLCNGGITSRYVRKLEATVDMPLDSDVFRVPCGYNAPQQVHITQGDVEGKAVIVSWVTQEAKGSNKVIYWKENSTKKHKAHGKTNTYKFYNYTSGFIHHCPIRNLEYDTKYYYVLGVGQTERKFWFFTPPEIGPDVPYTFGLIGDLGQSYDSNITLTHYENNPTKGQAVLFVGDISYADTYPDHDNRRWDSWGRFAERSTAYQPWIWTTGNHELDFAPEIGENRPFKPFTHRYRTPYRSSGSTEPFWYSIKRGPAYIIVLASYSAYGKYTPQYQWLEEEFPKVNRTETPWLIVLMHSPWYNSYDYHYMEGETMRVMYEAWFVKYKVDVVFAGHVHAYERSERVSNIAYNVVNGICTPVKDQSAPVYITIGDGGNIEGLATKMTEPQPKYSAFREASFGHAIFSIKNRTHAHYGWHRNHDGYAVEGDRMWFYNRFWHPVDDSPSCNS
Protein: Transportin-3 (Q7ZW13)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Serine/arginine-rich splicing factor 1B
- Serine/arginine-rich splicing factor 1A
- Small nuclear RNA-activating complex, polypeptide 3.
- FLJ10613-like-like)
- GTP-binding nuclear protein Ran
- Adhesion G protein-coupled receptor D1
- Bifunctional glutamate/proline--tRNA ligase
- Importin subunit beta-1
- Exportin-T
- U6 snRNA-associated Sm-like protein LSm8
Sequence:
MEGGKPTLPLVYQAVQALYHDPDPAGKERASVWLGELQRSMYAWEISDQLLQLKQDIESCYFAAQTMKMKIQTSFYELPPDSHTALRDSLLSHIQNLKDLSPIIVTQLALAIADLALQMASWKGCVHTLIEKYSNDVSSMTFLIEILTVLPEEVHSRSLRIGANRRTEIIEDLAYYSTTVVTLLVTCAEKSGHDEKMLIKVFRCLGSWFNLGVLDNNFMANNQLLMILFQVLQRDETSTNLHEAASDCVCSALYAIENVAIHLPLAMQLFQGVLTLETAYHMAVAREDLDKVLNYCRIFTELCETFLEMTVRTPGQGMGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKINDPALHNVFRPYIQRLLHSLARHCQLDPDHEGVPEDTDDFGEFRMRVSDLVKDVIFLVGSMECFAQLYSTLREGNPPWEVTEAVLFIMASIAKNVDPENNPTLMEVLEQIVLLPETVHLAVRYTSIELVGEMSEVIDRNPSMLDTVLNFLMKGLREKPLASAAAKAIHNICSVCRDHMAQHFQGLLDIARSLDSFALSTDAAVGLLKGTALVLARLPLEKIAECLNDLCAVQVMALKKLLAQDSSSGKSSDPTVWLDRLAVIFRHTNPIVENGQTHPCQKVIQEIWPVLSETLNAHQSDNRIVERCCRCLRFAVRCVGKGSASLLQPLVTQMVSVYQLYPHSCFLYLGSILVDEYGMEEGCRQGLLDMLQALCMPTFQLLEQPNGLRNHPDTVDDLFRLATRFVQRSPVTLLSSSIIVHIIQCAIAATTLDHRDANCSVMKFIRDLIHTGVTNDHEDDFEVRKRLIGQAMEQHGQQLVNQLINTCCFCLPPYTLPDVAEVLWEIMVFDRPTFCRWLETTLKGLPKETAGGAVTVTHKQLTDFHKQVTSAEECKQVCWAIREFTRLYR
Protein: MADS-box transcription factor 51 (OsMADS51) (OsMADS65) (Q9XJ61)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor involved in the regulation of flowering time under short day (SD) conditions. Functions as promoter of flowering under SD conditions, upstream of EHD1, HD3A and MADS14, but downstream of GIGANTEA (GI). May transmit a SD promotion signal from GI to EHD1. Functions independently of MADS50 to control flowering time.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
Interaction partners:
Sequence:
MARRGRVQLRRIEDKASRQVRFSKRRAGLFKKAFELALLCDVEVALLVFSPVGKLYEYSSSSIEGTYDRYQQFAGARRDLNEGSTSINSDENASIHSRLRDITAWSLQNNADESDANQLEKLEKLLTNALRDTKSKKMLAKQNGEGSRSRANSSGSRGQEEGSA
Protein: Endoplasmic reticulum protein 44 (Endoplasmic reticulum resident protein 44) (Thioredoxin domain containing 4 (Endoplasmic reticulum)) (Q6P3G9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Peroxiredoxin 4.
- DnaJ homolog subfamily B member 11
- ERO1-like protein alpha
- Peroxiredoxin-2
- Peroxiredoxin 3.
- Lectin, mannose-binding, 1.
- Sulfatase-modifying factor 1.
- thioredoxin-dependent peroxiredoxin
- Zinc finger protein 385A.
Sequence:
MKLSSIIPVPELHYFTLLLVTGLYNPGRGEITSLDSGNIDDILNGAGVALVNFYADWCRFSQMLHPIFEEASNIVREEYPDATQVVFGRVDCDQHSDLAQRYRISKYPTLKLFRNGMMMKREYRGQRSVTAIADFIRQQKVDPIKEIENLEEISTVDRSRRTIIGYFEKRDSDNYRTYEKVANILRDDCAFLAAFGEVSKPERFSGDNIIYKPLGENAPDMVYMGSLTNFDLSYAWTQDKCVPLVREITFENGEELTEEGIPFLILFHQKDDTESLEKFQQEVARQLISEKGSINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFPEFSDLAVPGKLRQFVLDLHSGKLHREFHHGPDPTDSTPGQQEENREVPSNPPESSFQKLAPSETRYTILRDRDEL
Protein: ABC transporter D family member 1 (ABC transporter ABCD.1) (AtABCD1) (EC 7.6.2.4) (Peroxisomal ABC transporter 1) (AtPXA1) (Protein ACETATE NON-UTILIZING 2) (Protein COMATOSE) (Protein PEROXISOME DEFECTIVE 3) (Ped3p) (Q94FB9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Contributes to the transport of fatty acids and their derivatives (acyl CoAs) across the peroxisomal membrane. Provides acetate to the glyoxylate cycle in developing seedlings. Involved in pollen tube elongation, ovule fertilization, and seeds germination after imbibition (controls the switch between the opposing developmental programs of dormancy and germination), probably by promoting beta-oxidation of storage lipids during gluconeogenesis. Required for biosynthesis of jasmonic acid and conversion of indole butyric acid to indole acetic acid. Confers sensitivity to monofluoroacetic acid (FAc), a toxic acetate analog, and to 2,4-dichlorophenoxybutyric acid (2,4-DB) and indole-3-butyric acid (IBA), two precursors of auxin after beta-oxidation.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:12065405}; Multi-pass membrane protein {ECO:0000255}. Glyoxysome membrane {ECO:0000269|PubMed:11828016}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Peroxisomal nicotinamide adenine dinucleotide carrier
- Peroxisome biogenesis protein 16
- Peroxisomal membrane protein PEX14
- Long chain acyl-CoA synthetase 7, peroxisomal
- Peroxisome biogenesis factor 10
- Peroxisome biogenesis protein 19-2
- Peroxisome biogenesis protein 19-1
- Peroxisome biogenesis protein 5
- Long chain acyl-CoA synthetase 6, peroxisomal
- Peroxisomal ATPase PEX6
Sequence:
MPSLQLLQLTERGRGLVASRRKSILLAAGIVAAGGTAVYLKSRVASRRPDSSRLCNGQSDDDETLEKLTATDQNAKITTKKKKGGGLKSLQVLTAILLSQMGKMGARDLLALVATVVFRTALSNRLAKVQGFLFRAAFLRRAPLFLRLISENIMLCFMLSTLHSTSKYITGALSLRFRKILTKIIHSHYFENMVYYKISHVDGRITHPEQRIASDVPRFSSELSDLILDDLTAVTDGILYAWRLCSYASPKYIFWILAYVLGAGTAIRNFSPSFGKLMSKEQQLEGEYRQLHSRLRTHSESIAFYGGETREESHIQQKFKNLVSHMSHVLHDHWWFGMIQDFLLKYLGATVAVILIIEPFFSGHLRPDDSTLGRAEMLSNIRYHTSVIISLFQALGTLSISSRRLNRLSGYADRIHELMAVSRELSGDDKSSFQRNRSRNYLSEANYVEFSDVKVVTPTGNVLVEDLTLRVEQGSNLLITGPNGSGKSSLFRVLGGLWPLVSGHIVKPGVGSDLNKEIFYVPQRPYMAVGTLRDQLIYPLTSGQESELLTEIGMVELLKNVDLEYLLDRYQPEKEVNWGDELSLGEQQRLGMARLFYHKPKFAILDECTSAVTTDMEERFAAKVRAMGTSCITISHRPALVAFHDVVLSLDGEGGWSVHYKRDDSALLTDAEIDSVKSSDTDRQNDAMVVQRAFAAARKESATNSKAQSYQTQLIARSPVVDKSVVLPRFPQPQTSQRALPSRVAAMLNVLIPTIFDKQGAQLLAVACLVVSRTLISDRIASLNGTTVKYVLEQDKAAFVRLIGLSVLQSGASSIIAPSLRHLTQRLALGWRIRLTQHLLRNYLRNNAFYKVFHMSGNSIDADQRLTRDLEKLTADLSGLLTGMVKPSVDILWFTWRMKLLTGQRGVAILYTYMLLGLGFLRRVAPDFGDLAGEEQQLEGKFRFMHERLNTHAESIAFFGGGAREKAMVDKKFRALLDHSLMLLRKKWLYGILDDFVTKQLPNNVTWGLSLLYALEHKGDRALVSTQGELAHALRYLASVVSQSFMAFGDILELHKKFLELSGGINRIFELDEFLDASQSGVTSENQTSRLDSQDLLSFSEVDIITPAQKLMASKLSCEIVSGKSLLVTGPNGSGKTSVFRVLRDIWPTVCGRLTKPSLDIKELGSGNGMFFVPQRPYTCLGTLRDQIIYPLSKEEAEKRAAKLYTSGESSTEAGSILDSHLKTILENVRLVYLLERDVGGWDATTNWEDILSLGEQQRLGMARLFFHRPKFGVLDECTNATSVDVEEQLYRVARDMGVTFITSSQRPALIPFHSLELRLIDGEGNWELRSIEQTTE
Protein: PBX homeobox 1 (H0YLF5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN
Protein: Axin interactor, dorsalization-associated protein (Axin interaction partner and dorsalization antagonist) (Q96BJ3)
Organism: Homo sapiens (Human)
Function: Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
Interaction partners:
Sequence:
MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE
Protein: Fatty acyl CoA synthetase 4 (EC 6.2.1.3) (Q9U401)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MGGCVISVMDYMNNRSEVENEHVKKFRALGKVAVPVPGSETSDCSPIYRLVTDDGKDIEEVRREWYEGECLPQRFAALCKRQPKQRALAYRPVDRVEKAVIKDLHTGTEKMMNVTHFKETKYLDYGTFWDYIESFGRGLVELGISPSSRVAIYEETRWEWLATIYGIWSQNMVATTVYANLGEDALAYALRETGCKGIICNAKNVSVVIKFMSEGITPSAPIIYNGSLPASVDQEACHLVSWEEVVKLGREARDRLPLNNSGRADDLALIMYTSGTTGDPKGVIHTHGSLMSGVHALDHRLNAVMGPLRDGETYLSYLPLAHILELGVLSVFIARGALICFGSPFTLTDLTARPRGDLAEYNPSLLIGVPRIYDTLKKAIQAKLPAPGTFKRRAFDHAFQSRLRAFKDGKDSPYWDAKVFAATRAVLGKNMYMVLSGGGPLSTATQDFLNVAVVRIIQGWGLTETVCVGGVQLTGDIETGAVGPPLLSEEVKLLDVEGYKHTDEPDPRGEILLRGPFLFKGYYKQEELTKEAIDEDGWFHTGDVGSIGPNGTLRIIGRVKALAKNVLGEYVAMETLESMYAHNSLSMPNGVCVLVHPDRPYICALVLTDEAKVVAFTREHGLKGKYPEVLQDPEFQKKATASFQETARASDRQKFEIVRHVRLLSDEWTPENGVLTAAGKLKRRVIDEKYTDTIVSLFVEEC