wanglab/gogpt-training-data huggingface dataset:
Protein: Dyschronic, isoform G (M9PF56)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell projection {ECO:0000256|ARBA:ARBA00004316}.
Interaction partners:
- Myosin 28B1, isoform B
- Myosin-VIIa
- Uncharacterized protein, isoform D
- Cadherin-99C
- LD33695p
- Calcium and integrin-binding family member 2
- Peripheral plasma membrane protein CASK
- No mechanoreceptor potential B, isoform D
Sequence:
MRLGGSGIPYDGDPLTMSAAGNDYAELCDLGPSRWSARPYGYNATAAAAASFGLGPSMGGTQSSSSVPTGGSAGLSGHHLRSSGAPGPSSFEAEDIGMAFGMISPPPGSGPYVGSSAAAGGSRVGNSTSSLRGAGGRSGLYYSPPGTSYTIVERPHSPHYYFNSAGVPTKGGSLPGRGSAYLSSSPASHMAAGTAGTLPTSTAASGRSMGQHASSNGNKKRPISPEQVLRMFGATQSSSVPTSSYHYSNGGTRDRDRTGRRSPASSPPSTTHQIYRDRERERDRSVPNIHELTTRTVSMSRDQQIDHGFGICVKGGKDSGLGVYISRIEENSVAERAGLRPGDTILEVNGTPFTSINHEEALKRCVQILKSSRQISMTVRAPPTLNSTAPLHGFGPPSRDPMYASMAPPLHPQNQAAAAAAAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDVTHDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEKARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEKHTLVTEIRELVFPEDRTRYDELVYRRERDPYSVDRHRRKGDPARDLPVTADDLEIIAATGRSPSSDSGLGMTVTDIYKRPALQLPHRPMSAGPILHRSQPASHYQTGSNQSSSSLSPPQQQQQQQQHYQPHHASLRHLGGIGGNVGSGRHHHHPLGPSQLKFRQTKDNQQQEYGCDEHRTRRGSETLLPEYEPDAEQELATKLSRSFDMKEEGGTLLGDKGVRRHQSMQRLSAEQNGGSTTEQTHEHNPNVVPDHRGNLHITVKKTKPILGIAIEGGANTKHPLPRIINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLVVEAKKSNLEPKPTALIFLEAXHLLALPASDPLERQKLEFLYEWGIDLTETPKPMPTPIPLTKAKNPPPLPHELHNNINSQYGSSAALSNHQPHQHTHPHPQQQQQQQQHSNTKTPNTNSNKTQGTPTTGTGAATTGSKQQQQPGNTTNTPTKASREATPTREQHHQHATPTREHQQQTPTRQQQLQREQQQQLQREQQQQHHRDRQQHFREQREQREREYQHEHEHEQHHHHHHHREHHEQHQHQHGHQHHPQHQHHHQYSSQQQHQRYSSSNSYKSHNNSVYQ
Protein: Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit) (P35251)
Organism: Homo sapiens (Human)
Function: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA.
Subcellular location: Nucleus.
Interaction partners:
- Replication factor C subunit 5
- Replication factor C subunit 4
- Replication factor C subunit 2
- Replication factor C subunit 3
- Proliferating cell nuclear antigen
- ATPase family AAA domain-containing protein 5
- Replication protein A 70 kDa DNA-binding subunit
- Cell cycle checkpoint protein RAD17
- DNA ligase 1
- Chromosome transmission fidelity protein 18 homolog
Sequence:
MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKKAASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKKMVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKKARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHSKSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSSPAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIRTMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAKTIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAKKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPSWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDVVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIKASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKGKGKSSKK
Protein: Aquaporin-2 (AQP-2) (ADH water channel) (Aquaporin-CD) (AQP-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct) (P34080)
Organism: Rattus norvegicus (Rat)
Function: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:19794145, ECO:0000269|PubMed:8429910}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P41181}. Basolateral cell membrane {ECO:0000269|PubMed:19794145}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P41181}. Cell membrane {ECO:0000269|PubMed:7508187}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P41181}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:19794145}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P41181}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:19794145}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P41181}. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated. {ECO:0000269|PubMed:19794145}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit alpha
- Vasopressin V2 receptor
- Solute carrier family 12 member 1-chloride cotransporter 1)
- Aquaporin
- Aquaporin-11
- Uromodulin
- Epithelial sodium channel subunit gamma
- Sodium/hydrogen exchanger 3
- Aquaporin-3
Sequence:
MWELRSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGILVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAIIGSLLYNYLLFPSAKSLQERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA
Protein: High-affinity gluconate transporter (Gluconate permease) (Gnt-I system) (P39835)
Organism: Escherichia coli (strain K12)
Function: Part of the gluconate utilization system Gnt-I; high-affinity intake of gluconate.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- Thermosensitive gluconokinase
- Thermoresistant gluconokinase
- HTH-type transcriptional regulator GntR
Sequence:
MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLDKVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVVLTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGPTAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEEMPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFTFGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNISPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI
Protein: Amino-acid permease RocE (P39137)
Organism: Bacillus subtilis (strain 168)
Function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Arginase
- Ornithine aminotransferase
- Protein RocB
- 1-pyrroline-5-carboxylate dehydrogenase
- Uncharacterized symporter YhjB
Sequence:
MNTNQDNGNQLQRTMKSRHLFMISLGGVIGTGFFLGTGFTINQAGPLGAVLSYLVGGFIMFLTMLCLGELAVAFPVSGSFQTYATKFISPAFGFAFGWLYWLGWAVTCAIEFLSAGQLMQRWFPHIDVWIWCLVFAALMFILNAITTKAFAESEFWFSGIKILIILLFIILGGAAMFGLIDLKGGEQAPFLTHFYEDGLFPNGIKAMLITMITVNFAFQGTELIGVAAGESEDPEKTIPRSIKQTVWRTLVFFVLSIIVIAGMIPWKQAGVVESPFVAVFEQIGIPYAADIMNFVILIALLSVANSGLYASTRILYAMANEGQAFKALGKTNQRGVPMYSLIVTMAVACLSLLTKFAQAETVYMVLLSLAGMSAQVGWITISLSQIMFRRKYIREGGKIEDLKFKTPLYPVLPLIGLTLNTVVLISLAFDPEQRIALYCGVPFMIICYIIYHVVIKKRQQANRQLEL
Protein: 3-isopropylmalate dehydratase (EC 4.2.1.33) (Alpha-IPM isomerase) (Isopropylmalate isomerase) (Q5B0P4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- 2-isopropylmalate synthase
- 3-isopropylmalate dehydrogenase
- 3-isopropylmalate dehydrogenase
- ACT domain-containing protein
- Multifunctional tryptophan biosynthesis protein
- homocitrate synthase
- ASST-domain-containing protein
- D-lactate dehydrogenase, putative
- L-lactate dehydrogenase
- Pyruvate kinase
Sequence:
MPGADRKPKTLYDKVFDHHIVNEQEDGTVLIYIDRHLVHEVTSPQAFEGLKNANRKVRRPDCTLVTVDHNIPTSSRKNFKNVEQFIEENDSRLQCSTLEENVKDFGLTYFGMDDKRQGIVHVIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLITRRSKNMRVQVDGELPAGVTSKDVVLHIIGLIGTAGGTGCVIEFCGSVIRGLSMEARMSMCNMSIEGGARAGMVAPDETTFEYLKGRPLAPKYDSAEWKKAVSYWSSLASDEDAVYDKTILIDAKDIVPTISWGTSPQDVVPITGVVPGPDDFEDEARKAACKRALEYMGLTAGTPMKDVTVDKVFIGSCTNSRIEDLRAAANVVRGKKVASNIKRAMVVPGSGLVKQQAEAEGLDKIFIDAGFEWREAGCSMCLGMNPDILSPQERCASTSNRNFEGRQGAGGRTHLMSPAMAAAAAIVGKLADVREHIAESPRLGKVQPKVDVKPEAEDVDTEEELDHILDQPADNEPHTNTHTPATTSAGLPKFTTLKGIAAPMDRSNVDTDAIIPKQFLKTIKRTGLGSALFYELRYKDGQEDPSFILNQGIYRNSKILVVTGPNFGCGSSREHAPWALLDFGIKCVIAPSFADIFFNNTFKNGMLPVVIPDQAVLEKIADEARAGREVEVDLVNQEIKDEAGNKLASFDVDAFRKHCLINGLDDIGLTLQMEDKIAKFEAKRTLDTPWLDGKAYLKRGRTGGSNMVKAAPVPKTNRGDVKGEPLEW
Protein: Gasp (O97377)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKKFLVVFVALFGAAVAQSSFKCPDDFGFYPHDTSCDKYWKCDNGVSELKTCGNGLAFDATDSKYLTENCDYLHNVDCGDRTELEPPITTPHCSRLYGIFPDENKCDVFWNCWNGEPSRYQCSPGLVYDRDARVCMWADQVPECKNEEVANGFSCPAAGELANAGSFSRHAHPEDCRKYHICLEGVAREYGCPIGTVFKIGDSDGTGNCERSRGCSRV
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (Q8IGT4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MQNGKPRSSARPSFHRRPKDGVANTTTDNAAVKPEALESYTGNDDNACVVCFKNVEIFSIGDCDHPVCYECSTRMRVLCQQNECPICRHVLSKVLFTLDKLPYRELEANNRSDLYSKKYRIGFCTAEIRQQFFKLLDHPCPKCDAPPYRTFEGLRNHVRSEHKLLYCDLCVETLNIFTFERRCYTQAELQLHNTKGDPDNRSHRGHPLCEYCNKRYVDRDELFRHLRREHYFCHFCDADGCNEFYNDYADLAEHFRAEHFLCEEGKCATEQFVGAFRNEIEYKAHVANVHGKSLNKQQAKQTRTLQVEITLGPRGRSGQTEQGITSVRTRNDEHNDYQNDLPSITQRHVSIDAGNEEQFPTLRGASTAPSVSLVRPPPPSMRNLSGTSGLARTKENFPALGGGNGGGVTGPTSSSIAARAAQSQHPVAAVFKKPTSAAGSGSRSGPPGNGMLLHVSNRSAAVPKKAATPQVDFPALPGKGNKKNLRNLEEDMLPSGSPVPMANISAKHRSLADDYVSVASPSTFQKLQMVQKEEDEAKARQEALKKSAPKLTAAEFPSLGPSASASSSRTTAQKPSSGSPSLNWSKPANEKKQRELENRKAKVAPAPVLPSPTSKPAPKASNNNVQEQQANKKDKKQKDKKSNQENQPKTAKPKERNNNNEQKTNGAPSTPIRAPPGLKPGGPLKPPPGFVSNVTVNSVAKLPNNLTFTNSLGESYDIVPSPYTYTDPPDTEVRNQKLVDEVMSLLKTPEALNEFRLLSSKFRDGSCSGQAYYEHCQCAMLSSFYNLFPELLAMLPDISKQQELYLVHKQHLNSLPPAERKSVPALEVCKVCKQILITADLKSHQQAHELTKNFPVLGSSASNTHRN
Protein: Non-structural maintenance of chromosome element 5 (Non-SMC element 5) (O94668)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. May prevent formation of excessive Holliday junctions or assist in their resolution.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16478984, ECO:0000269|PubMed:16823372}. Chromosome {ECO:0000269|PubMed:16478984}.
Interaction partners:
- Non-structural maintenance of chromosome element 6
- Structural maintenance of chromosomes protein 5
- Structural maintenance of chromosomes protein 6
- Non-structural maintenance of chromosome element 4
- Non-structural maintenance of chromosome element 3
- Non-structural maintenance of chromosomes element 1
- E3 SUMO-protein ligase nse2
- BRCT-containing protein 1
Sequence:
MNSALKAIIELCIEEDLLPKSLDVLEYLLSTTSIPIPACYIRMCITLLVHPEYPTSSNIQESCNWILQQVVENRSKINFDAWSFENDLSDNDMPKENYLKIFSNQCLFTQDVDYWDLIAYMSSRPPDLERWMSLMDIWLRILEIDAEENGSALMKKYMGEDLCELQDAIRICFSCFTLPQQTMESPFATSMSKAPAKTESRGSNSFEGTSRLANLGAKLLCLIWAMLPKGRFFVVHLTDAFHFLSKLDERFSKLNAKQQDLFFGNLGASNLRYCLSQYILMKGIGIGINIRHTRCEFTKQLTQLLPTSLPKNKIRQKLHLRAWVSFLGSALRESDRNFDKELFYTTLKQLYTMYQQTELVGIDRPMAILKDMLVLLDISKKLSLDKIV
Protein: Rhomboid-related protein 2 (RRP2) (EC 3.4.21.105) [Cleaved into: Rhomboid-related protein 2, N-terminal fragment (NTF); Rhomboid-related protein 2, C-terminal fragment (CTF)] (A2AGA4)
Organism: Mus musculus (Mouse)
Function: Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3 (By similarity).
Subcellular location: [Rhomboid-related protein 2, C-terminal fragment]: Cell membrane {ECO:0000250|UniProtKB:Q9NX52}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Nicastrin
- Gamma-secretase subunit PEN-2
Sequence:
MAVAHEMEMESVNLNMEREGKEEPEEEKMKGNGEGKDFPRSRKVHRIVSKWMLPEPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVWKPQKQWITLDTGILESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAFGIVRLLVIILIVASDMGFALYRRFFVPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN
Protein: GPN-loop GTPase 3 (Q8W4C1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- GPN-loop GTPase QQT2
- Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog
- AT5G18310 protein
- Pathogenic type III effector avirulence factor Avr AvrRpt-cleavage: cleavage site protein
- Leucine carboxyl methyltransferase
- MJK13.9 protein family protein)
- RNA-binding
- Transcriptional elongation regulator MINIYO
- AT5g02480/T22P11_70
- Nucleolar protein
Sequence:
MGYAQLVIGPAGSGKSTYCSSLYEHCETIGRTMHVVNLDPAAEIFNYPVAMDIRELISLEDVMEDLKLGPNGALMYCMEYLEDSLHDWVDEELENYRDDDYLIFDCPGQIELFTHVPVLKNFVEHLKQKNFNVCVVYLLDSQFITDVTKFISGCMSSLAAMIQLELPHVNILSKMDLLQDKSNIDDYLNPEPRTLLAELNKRMGPQYAKLNKALIEMVGEYGMVNFIPINLRKEKSIQYVLSQIDVCIQFGEDADVNIKDDDDFSDDGPDL
Protein: 26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1) (P62191)
Organism: Homo sapiens (Human)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC1 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Subcellular location: Cytoplasm. Nucleus. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 1
- 26S proteasome non-ATPase regulatory subunit 14
- Proteasome subunit beta type-2
- 26S proteasome regulatory subunit 10B
- Proteasome subunit beta type-3
- 26S proteasome non-ATPase regulatory subunit 8
- Proteasome subunit alpha type-3
- Proteasome subunit beta type-1
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 12
Sequence:
MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL
Protein: Transcription repressor OFP15 (Ovate family protein 15) (AtOFP15) (Q9SJ45)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription repressor OFP7
- Transcription repressor OFP6
- Transcription repressor OFP2
- Transcription repressor OFP8
- Transcription repressor OFP5
- Transcription repressor OFP1
- Transcription repressor OFP17
- Transcription repressor OFP10
- Transcription repressor OFP4
- Transcription repressor OFP3
Sequence:
MKLPFLNKNHSTSSYSSNSSSSSWPWPSCNQNPKTLSFRATITFTNPIHDQDDDELDLLDPPEITDSVENVIKGLRSSERLIFESKGETNSILEEATSKREEEDEEEGFMLFSLESDDPYSDFKRSMEEMVEAHALHHDWKSLEKLLLQFLKVNAKTSHRYIFAAFVDLLMNLALDTKKAIINNDISKDDGVSASRAAAAGEASTSCCNSMTLGESPSSPLSFYTSCSSSSSSDETSSMSVRFLPLSSLLEMDEKTKEILV
Protein: Uncharacterized protein (Q57ZJ7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Protein RER1
Sequence:
MSAFEDNPFAEDDGEPTASQLSTTRKRAREGDDSDAVGTGTSANPSLFAIQQERWEKQKHDHEHFGGPSSTSSHSPATPGSAVHEANTGGGVPVEVVPTATLLAEYDTGLEEDEYNALVVKSAGLESEISRRDEEYAAELSAKTKDNESMQESVELLRATVLRVRQEMELCRRAKDSADANYYSGSDVINGDDAMVELMQMVEQECNTLQRLASDILQSSAPRIRELMETTDTAEEIRSRIVGVLGELPRLPSFDLQGERRYIEACRAAASKLDSEGPLGSSVLLIQALISELFLQLQNCESVYGSVELLSTRVMAIVSSLQELVHDSLEWYFRTRSRAFSGNSSLSFNANNLLPPEVFSAEVDIRQMNTTLHHLDATLSHLQALPHVVSLSHQNAPSVFAMSVTTLCEELESEAEELGLEVLRLRKLFNLDASTLVSNAGEPQESSCTDEDCMKNGASSEKVKWLNLLSQKLLKQNSSAAALCRTLRDATVDNDSPVVNLQMLFYRCYSEIQGLLLQSLTSLNRVLQQRARIVEHIRQVVMLDGDDEAFALCAERVFQGSEDGVEGLLDEMEESSRACIHQFSEASSKALDELMMRNQQNVQRLLEVRRFFIQVAENTDQLAYGGAAEGLRRVLHDAVEQQRRLTVSEETHQSEEPLEISVESDENGFGDVLDIVASEHKEELREEIQFARRRGEELLKRRKWLAMQPTHKDLLELLAVHKEVKAVKEKLALAAQRQAKWAAAKEALEVKRRQVAEAQVAVLEKQSKLRELQQKLQPTGPFGSW
Protein: Tailup (Q9Y0Z9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MVMAEIGGHLAHQLPLHNHNHNQTGLQPSLVMNHHLDLDCHGHDVIKKQRLSHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSSQSSLTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNGMPILPPHPHSHPAQGPPHQHPPPPGGPHNHQNQQPNQQPGGSSLDSGITSHHHPDSTDSYVTYLESDDSMQGSP
Protein: Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 (Q9D489)
Organism: Mus musculus (Mouse)
Function: Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:16765102, ECO:0000269|PubMed:28504655}. Cytoplasm {ECO:0000269|PubMed:28504655}. Note=Translocates from the cytoplasm into the nucleus and the translocation is dependent on SOHLH1 protein expression. {ECO:0000269|PubMed:28504655}.
Interaction partners:
- Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
- Deleted in azoospermia-like
- Homeobox protein NOBOX
- Stimulated by retinoic acid gene 8 protein
- Factor in the germline alpha
- Nanos homolog 2
Sequence:
MADRISTGELGRRPGQGRVNLLLVGDATRYFLAGSMQKFFPSTAQITLTISNVKKVAVLLAANSFDIIFLKVTSTLTAEEQEAAKLIRSGKKKNTHLLFAFVIPERLKGYVSEYGADISFSEPLTLEKVNTVIHYWKTYFTNTDMENTELPPECRLYFQTSRSELGGRFSTDMFLCSELLKNDARLGLKAPLSSLDKSKQASFLHSTKEKLRRERIKSCCEQLRTLLPYVKGRKSDVASVIEATVDYVKQVRESLSPAIMAQVTEAIQNNRRFSKRQMPIELFLPFSATSQREDAMLTSAFSPVQEIQLLADRGLNVYSMTAAGGALEGAVRGQPGSVSESSIEDLYKTRVPSTARSLNSFHSVKYTSGTVSPHEAAARTNQNISTYLPPTAPSVSNFIPQHCNAMLCPARPTSPNCLCTPGHELAASSRAASASIFRGFRAASASDHQASQPPALPSPQPHDSSYF
Protein: Probable acetolactate synthase small subunit (Acetohydroxy-acid synthase small subunit) (AHAS) (ALS) (O60086)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Stimulates activity of the acetolactate synthase catalytic subunit ilv1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Acetolactate synthase, mitochondrial
- Threonine dehydratase, mitochondrial
- Probable ketol-acid reductoisomerase, mitochondrial
- 2-hydroxyacyl-CoA lyase
- 3-isopropylmalate dehydrogenase
- Dihydroxy-acid dehydratase, mitochondrial
- 2-isopropylmalate synthase
- Homoserine dehydrogenase
- 3-isopropylmalate dehydratase
- Aspartate-semialdehyde dehydrogenase
Sequence:
MFARRCGRLANRFVRLKSTSATSPITYKALHANSPLPRCRIIEPPRATVPEAVSNIIMSTPFNRVQRPKRHVFNCLVQNEPGVLSRLSGILAARGFNIDSLVVCATEVENLSRMTIVLRGADEVVEQAKRQIEDIVSVWAVLDYTGTSMVERELLLAKVSLLGPDHFQEHFERSEKVAESTNAKAKSDGEGVMNANAALQLRASQLAAINQLTTLFHGRVADISTETIILELTATPDRVDNFLSLLRPYGVLEACRTGTSAMTRAPHSNEVTEEAEDDVEVEEVFLPPG
Protein: Actin A (EC 3.6.4.-) (P12432)
Organism: Trypanosoma brucei brucei
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
Sequence:
MSDEEQTAIVCDNGSGMVKSGFSGDDAPRHVFPSIVGRPKNEQAMMGSANKKLFVGDEAQAKRGVLALKYPIEHGIVTNWDDMEKVWHHTFYNELRVNPESHNVLLTEAPMNPKQNREKMTQIMFETFGVPAMYVGIQAVLSLYSSGRTTGIVLDAGDGVTHTVPIYEGYSLPHAIRRVDMAGRDLTEYLMKILMHTGMTFTTSAEKEIVRNIKEQLCYVALDFDEEMTNSAKSVSEEPFELPDGNVMQVGNQRFRCPEALFKPALIGLDEAPGFHEMTFQSINKCDIDVRRDLYGNIVLSGGTTMFKNLPERLAKEISNLPPSSIKPKVVAPPERKYSVWIGGSILSSLTTFQSMWITKSEYDESGPSIVHSKCF
Protein: Spermatogenesis associated 24 (D6R9Q3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATPLGWSKAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAVKSKVLQESSKKDQLITKCNGRREARALHHGYINGLFPNHPVPVSKAGFHSNTCPQLRIQAGPGGPHLRKGLKGPGRPRK
Protein: Glucosaminyl (N-acetyl) transferase 2 (I-branching beta-1,6-acetylglucosaminyltransferase family polypeptide 1) (Q6T5E1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323}.
Interaction partners:
Sequence:
MGSWKYSLFSLALIAALTFMFISNNKLWENNHFPRAIPNSSVLAEVCFQMFSEESFYAVDSTRKTTLEKFTCSEYRVQNHYITEALSEEEARFPLAFTLTIHKDYDTFERLFRAIYMPQNVYCVHVDSKAAETFKEAVRQLLSCFPNAFLASRMERVVYGGFSRLQADLNCMRDLVASKVPWKYVINTCGQDFPLKTNREIIQYLKGFLGKNLTPGVLPPAHAVGRTKYVHRELLDLKNPYVHNTARLKTPPPHNLTIYFGTAYVALTREFANFVLTDQRSLDLISWSKDTYSPDEHFWVTLNRIPGVPGAMPNASWTGNLRAVKWKDMESQNGACHGHYVHDICIYGNGDLQWLINSQSLFANKFEVNTYPLTVECLELRLRERTLNQSDIALQPSWHF
Protein: Karmoisin, isoform A (RH42588p) (Q9VG39)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAENEPLNDLQSQVNGRILPAANGHTASATNGLVHANGKDAMKPSAPVQNGNGNANGTHIEAPCCRDIHGKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLHPPPEPPKKKPGRSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVKTTFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVKEEENGVSAPRAVVLANGDIEIAGNGHYRSAGTKSSAPLMGATNGINGSAPASPTIQSNGHVDNGTGKLAVTNGSAS