wanglab/gogpt-training-data huggingface dataset:
Protein: Ras-related protein RABF2b (AtRABF2b) (Ras-related protein Ara-7) (Ras-related protein Rab5B) (AtRab5B) (Q9SN68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Endosomal protein that may be involved in endocytosis. Involved in the trafficking of proteins from prevacuolar compartments (PVCs) to vacuoles. May activate the MON1-CCZ1 complex which acts as guanine nucleotide exchange factors (GEF) for Rab7 protein family, and serves as a link between Rab5 and Rab7 families in PVCs, and mediates PVC maturation. Involved in vacuolar transport of storage proteins with EREX as effector. Regulates membrane trafficking to protein storage vacuoles (PSVs).
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:11532937, ECO:0000269|PubMed:23482856}; Lipid-anchor {ECO:0000305}. Endosome membrane {ECO:0000269|PubMed:15608333, ECO:0000269|PubMed:16103374, ECO:0000269|PubMed:24824487}; Lipid-anchor {ECO:0000305}. Prevacuolar compartment membrane {ECO:0000269|PubMed:15509844, ECO:0000269|PubMed:24824487}; Lipid-anchor {ECO:0000305}. Endosome, multivesicular body membrane {ECO:0000269|PubMed:23682115}; Lipid-anchor {ECO:0000305}. Cell membrane {ECO:0000305|PubMed:23519409}; Lipid-anchor {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:29463724}. Note=Strong co-localization with VPS3 and VPS18 in cytoplasmic puncta. {ECO:0000269|PubMed:29463724}.
Interaction partners:
- Vacuolar protein sorting-associated protein 9A
- Guanosine nucleotide diphosphate dissociation inhibitor At5g09550
- Vacuolar protein sorting-associated protein 45 homolog
- V-type proton ATPase subunit a1
- Protein SUPPRESSOR OF K
- Guanosine nucleotide diphosphate dissociation inhibitor 2
- Guanosine nucleotide diphosphate dissociation inhibitor 1
- Vesicle-associated membrane protein 727
- Syntaxin-21
- Vesicle-associated membrane protein 711
Sequence:
MAAAGNKSINAKLVLLGDVGAGKSSLVLRFVKDQFVEFQESTIGAAFFSQTLAVNDATVKFEIWDTAGQERYHSLAPMYYRGAAAAIIVFDVTNQASFERAKKWVQELQAQGNPNMVMALAGNKSDLLDARKVTAEDAQTYAQENGLFFMETSAKTATNVKEIFYEIARRLPRVQPTENPTGMVLPDRAMDRAVSSSCCA
Protein: Citrate synthase (O08395)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MTGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQDLAARCSFEQVAFLLWRGELPTDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVVRTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMRRRRGLPPIAPHSGLGYAQNFLHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGRLHGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALERVGTVRDGQRWLDIYQVLAAEMASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITGWTAHIMEQATANALIRPLSAYCGHEQRVLPGTF
Protein: Calcineurin B-like protein 7 (SOS3-like calcium-binding protein 3) (Q9SUA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19832944}. Nucleus {ECO:0000269|PubMed:19832944}.
Interaction partners:
- CBL-interacting serine/threonine-protein kinase 11
- CBL-interacting serine/threonine-protein kinase 24
- CBL-interacting serine/threonine-protein kinase 8
- CBL-interacting serine/threonine-protein kinase 23
- Peptidyl-prolyl cis-trans isomerase FKBP12
- CBL-interacting serine/threonine-protein kinase 6
- High affinity nitrate transporter 2.5
- High affinity nitrate transporter 2.4
- Translation factor GUF1 homolog, mitochondrial
- PLASMODESMATA CALLOSE-BINDING PROTEIN 5
Sequence:
MDSTRNSASSNSTGCFTDQKKRKALYEVFKKLSGVDCQRNEGNVVEGVTCYYGEMNKEQFHVAIFQTDKNESLFSERVFDLFDTNHDGLLGFEEFARALSVFHPSAPIDDKIDLSFQLYDLKQQGFIERQGVKQLVVATLAASGMSQSDEIVESIIDKTFVQADTKHEGMIDEEEWMDLVFRHPLLLKNMTLQYLKDITTTFPSFVLHSQVEDT
Protein: ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9) (Q9BW91)
Organism: Homo sapiens (Human)
Function: Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.
Subcellular location: [Isoform 1]: Mitochondrion.
Interaction partners:
- ADP-sugar pyrophosphatase
- Ribose-phosphate pyrophosphokinase 2
- Ribose-phosphate pyrophosphokinase 1
- Ribose-phosphate pyrophosphokinase 3
- Transient receptor potential cation channel subfamily M member 4
- Transient receptor potential cation channel subfamily M member 8
- Phosphopentomutase
- Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
- Transient receptor potential cation channel subfamily M member 5
- Transient receptor potential cation channel subfamily M member 3
Sequence:
MAGRLLGKALAAVSLSLALASVTIRSSRCRGIQAFRNSFSSSWFHLNTNVMSGSNGSKENSHNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNFSPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKRDSSGNKIMHPVSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQKTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLMLEAGDDAGKVKWVDINDKLKLYASHSQFIKLVAEKRDAHWSEDSEADCHAL
Protein: 2-oxoisovalerate dehydrogenase subunit alpha (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (Q38CH4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 3-methyl-2-oxobutanoate dehydrogenase
- Pyruvate dehydrogenase E1 component subunit beta
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Dihydrolipoamide dehydrogenase, putative
- Dihydrolipoamide dehydrogenase, point mutation
- Dihydrolipoyl dehydrogenase
- Dihydrolipoamide dehydrogenase, putative
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Branched-chain amino acid aminotransferase, putative
- Branched-chain amino acid aminotransferase, putative
Sequence:
MLRVSCRFFGALQEIFSRGQGVWNLDFGNSPTTEDLIFNSAPKTSTPPFHVLDLEGNIVNKINEPVVPKETLVKIMETMIRSNTIDNILLEAQRQGRISFYLTALGEEATVVGTAAGLEIRDEAFLQYREAGFLLYRGYNIPQLVAQCMGNVEDVLKGRQMPIHYGSRELNVHMVSSPLATQIPHAAGAGYAFRLENEELSDESKSRVAVVIFGEGAASEGDFHGGVNFAAATGSNTLFVVRNNGYAISTPARVQYKGDGVLARGIGYGIPSARVDGQDVLAILQAVQQARQIIRTTNQPVLIEALCYRLQHHSSSDDSGMYRSSDEIENFLALSPLDRFEKFLVKRDLWTAEHTGALAKQVREELLQELRRQELLPHWPADVMHDDVYKVKTPDLVKAQKELQAHYERNRGFYGK
Protein: Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) (P49286)
Organism: Homo sapiens (Human)
Function: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Melatonin receptor type 1A
- Melatonin-related receptor
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-4
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-5
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
Protein: Ras-related protein Rab-44 (Q7Z6P3)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
Sequence:
METGQRTSRKVRKLGSNRRRQTREPADGEGAAVAPEPESWSSQAAAELQAFFQDCGAKERGFVTREDLAVAKFSFLGSKEESEMIFDWVDVERKGHLSLEEFSSGLKNIFGSSQSPHRLRRRKPLPSKRVSATTSFPALEEADAEEKEAFLAFMEQLGTGHLLPKQMEIWQLWGQLRQEEPQLAGNLAGFLAKMTSRLQEAQADKEALELTLRKRDSDHHREVQQLYEEMEQQIRQEKQQLQAESDSRGLALTSQMQDVLEAKEREVQRLAEGQRELEAQLSHLRSTHQEAASENQQLQEAKRDLAGRLEEVRGQLQVTRGRLDAARGRVSWQVEEKLSFPGAGEKTPDPQAASPEEAPLPGLFGDNDDWDQLLSNFGSPPHGALQLCWSPPPTPRATSGPQTPRVVRQISISEPQAFLFGQEPSSDPDGAPRTPPGVTFSAKDNKGVDPHEQDIRAEQPVEPHDPDPNQEPGSTPEGRLLWGLSGSLVAPAFKVLIPLEDGPPPPANSPPPQAPAGSSKQIQASDPDDKGPGSWAPPSGAQPGAGAGPQEPTQTPPTMTERETQPGPSPTTALTGVGPAKPPRQRDALQQDLHATGSEPRLGTQRARALTLGPAEPFQGLEFVGPVPTERLEQGQAGPAVQEGLPEGLREAHGQVLGLGELSAFPHQELEEEPRSEEGKQEGRGGQDLSSEQSEQSVEAHGLETAHSELPQQDSLLVSLPSATPQAQVEAEGPTPGKSAPPRGSPPRGAQPGAGAGPQEPTQTPPTMAEQEAQPRPSLTTAHAEEQGPPHSREPRAESRLEDPGMDSREAGLTPSPGDPMAGGGPQANPDYLFHVIFLGDSNVGKTSFLHLLHQNSFATGLTATVGVDFRVKTLLVDNKCFVLQLWDTAGQERYHSMTRQLLRKADGVVLMYDITSQESFAHVRYWLDCLQDAGSDGVVILLLGNKMDCEEERQVSVEAGQQLAQELGVYFGECSAALGHNILEPVVNLARSLRMQEEGLKDSLVKVAPKRPPKRFGCCS
Protein: ATP-dependent Clp protease subunit, heat shock protein 78 (HSP78), putative (Q587G1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Heat shock protein 20, putative
- GrpE protein homolog
- Uncharacterized protein
- AAA+ ATPase domain-containing protein
Sequence:
MRKLGSGGRGVWANSLTTKRTVQVGGYSAVSLLPSTAPLCNGLSTLFGVQRRFQSSVTPWGGQQGGGSGSNSNSNTQQQQGRAWVNPQAVPPGEFLNKYARNLTEEARMGRLDPIIGREEIIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGEVPESIKDKKVFSLDMGSLVAGAKFRGEFEERLKGVLKDTIESQGKVILFIDELHTLVGAGASGDGSMDAANLLKPSLARGELHCVGATTLDEYKRHIEKDAALARRFQSVLVTEPTVEETISVLRGIKEKYEAHHGCLIKDEALVYAAVNSHRYLSERRLPDKAIDLIDEAASRLRLQQESKPEQLDSVGRELVRLKIEAEAVKKDKDELGKAKLTQLYNRIEERQKEYDALEERWKKEKAMFDRIKKRTEDLDVLRHHYEQARTEGDFAKASEILHGRIPALKKEIDADKQATRTENFLTHDSVTADDIAQVIARATGIPVAQLMTGEREKLITMDKELRQRVLGQDEAIATITNVVRISRAGLHAHKRPLGSFLFLGPTGVGKTEICKQLARFLFDDESFICRIDMSEYMERHAVHRLIGAPPGYVGYEEGGELTESVRRRPYQIVLFDEFEKAHPSVSNILLQVLDEGHLTDSHGRRVDFKNTIIILTSNIGADAIAALPEGCPSSKAMPSVMQQVRQRMTPEFINRLDDIVMFNRLGKAETRKIVDLLFAHVQSMLDDQEIKLEVSSDVFEWFGTNGYSPVYGARPLKRLVQSELLNRLAIMLLDGRIREKETVKVEMRDGEVFVHQNHDAVRPVDAADLGPQLTE
Protein: NAC family protein (Wood-associated NAC domain transcription factor 1A) (A9PDI0)
Organism: Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
Interaction partners:
Sequence:
MPEDMVNLSINGQSQVPPGFRFHPTEEELLHYYLRKKVAYERIDLDVIREVDLNKLEPWDIQEKCKIGSTPQNDWYFFSHKDKKYPTGTRTNRATAAGFWKATGRDKIIYSGFKRIGLRKTLVFYKGRAPHGQKSDWIMHEYRLDDSTHETNVSNPIGEAIPEEGWVVCRVFRKKNYQKTLESPKGSSSSLDSKAHQILGSGNEGVLDQILMYMGRTCKMENETFSNMNISNNSNSSSLRFLSNNCISEGLHERFMHLPRLESPTLPSIPIRSPSFDQDRSFISCYHQSYDEMLTENEPSSPNQVGNGIFDMTSSSMTDHDSKSGQLNDWVTLDRLVASQLNGHEVETSKQLSCFSTDPNASFGLSPDDGMQLSHKQHSHGSSSSNIQANSSHVYSNENDLWSLTKSSSPSSSSDPLCHLSV
Protein: Nucleolar protein 56 (Ribosome biosynthesis protein sik1) (O94514)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for 60S ribosomal subunit synthesis.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit cbf5
- rRNA 2'-O-methyltransferase fibrillarin
- Uncharacterized WD repeat-containing protein C2E1P5.05
- Ribosome biogenesis protein bms1
- Nucleolar protein 58
- 13 kDa ribonucleoprotein-associated protein
- U3 small nucleolar RNA-associated protein 21 homolog
- U3 small nucleolar RNA-associated protein 4
- U3 small nucleolar RNA-associated protein 10
- U3 small nucleolar RNA-associated protein 20
Sequence:
MADYLLYESATGYSLFDVVGADQIAAKTKEVQLSLQDISKFGKVVQLRSFIPFKNAAHALENANDISEGVLNDFLKNFLELNLPKASKKKKVSLGVQDKNLATSIKSEIDAIECDTSELTQDLLRGIRFHGDKLLKQLSPGDFERAQLGLGHSYSRAKVKFNVNRNDNMIIQAIAILDQLDKDINTFAMRMKEWYSWHFPELSKIVGDNYKYAVIVTLVGDKTTINDEMLHDLAAVVDDDKDIAQSIINAGKVSMGQDISEIDLENILSFAERVIKLSNYRKQLHNYLVQKMNVVAPNLAELIGEMVGARLISHAGSLTNLSKCPASTVQILGAEKALFRALKTRGNTPKYGIIYHSSFIGKAGAKNKGRISRFLANKCSIASRIDNFSDAPTTAFGQVLRRQVEERLNFFDTGVAPTRNSIAMAEAYEKALSSVNIDGDEEVDIDVEETVETISEKPSKKEKKDKKEKKKEKSKKKRSADDASEEVKKSKKKKKSH
Protein: Zinc transporter ZitB (P75757)
Organism: Escherichia coli (strain K12)
Function: Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc, whereas ZntA is required for growth at more toxic concentrations.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Zinc/cadmium/lead-transporting P-type ATPase
- Zinc transporter ZupT
- Zinc transport protein ZntB
- HTH-type transcriptional regulator ZntR
- Multicopper oxidase CueO
- High-affinity zinc uptake system protein ZnuA
Sequence:
MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGSLALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHVLGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH
Protein: Transcription factor MYB57 (Myb-related protein 57) (AtMYB57) (Q9SSA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor acting redundantly with MYB21 and MYB24 to control stamen filament elongation in the late developed flowers. Repressed at the transcript levels by DELLA proteins.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- CASP-like protein 2A2
Sequence:
METTMKKKGRVKATITSQKEEEGTVRKGPWTMEEDFILFNYILNHGEGLWNSVAKASGLKRTGKSCRLRWLNYLRPDVRRGNITEEEQLLIIQLHAKLGNRWSKIAKHLPGRTDNEIKNFWRTKIQRHMKVSSENMMNHQHHCSGNSQSSGMTTQGSSGKAIDTAESFSQAKTTTFNVVEQQSNENYWNVEDLWPVHLLNGDHHVI
Protein: Putative casein kinase II subunit beta-4 (CK II beta-4) (O80507)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a complex role in regulating the basal catalytic activity of the alpha subunit. The tetrameric holoenzyme CK2, composed of two alpha and two beta subunits, phosphorylates the transcription factor PIF1 after an exposure to light, resulting in a proteasome-dependent degradation of PIF1 and promotion of photomorphogenesis. CK2 phosphorylates translation initiation factors. May participate in the regulation of the initiation of translation.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:16926165}.
Interaction partners:
- Casein kinase II subunit alpha-3
- Casein kinase II subunit alpha-1
- Casein kinase II subunit alpha-4, chloroplastic
- Casein kinase II subunit alpha-2
- Protein CCA1
- FACT complex subunit SSRP1
- Ribosomal RNA-processing 7 protein
- Nucleolar protein
- FACT complex subunit SPT16
- FACT complex subunit
Sequence:
MYKDRSGGGIMGGGGSSRSEILGGAIDRKRINDALDKHLKKSSPSTSRVFTSKDKDSVPSTSTAKSQLHSRSPDVESDTDSEGSDVSGSEGDDTSWISWFCNLRGNEFFCEVDEDYIQDDFNLCGLSGQVPYYDYALDLILDVESSNGDMFTEEQHEMVESAAEMLYGLIHVRYILTTKGMAAMMEKYKNYDFGRCPRVFCCGQSCLPVGQSDIPRSSTVKIYCPKCEDIYYPRSKYQGNIDGAYFGTTFPHLFLMAYGNMKPQKPAQNYVPKIFGFKVHNKQ
Protein: Fascin (D3ZX02)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR005682}.
Interaction partners:
- U4/U6 small nuclear ribonucleoprotein Prp31
Sequence:
MPTNGLHQVLKIQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDHPGRDCRFLVLPQPDGRWVLQSEPHGRFFGGVEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALLTLIFQSRRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPGKDELFDLEQSHPQVVLVAANHRYVSVRQGINVSANQDEELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHGRRVALKASNGRYVCMKKNGQLAAISDFVGEDELFILKLINRPILVLRGLDGFVCHRRGSNQLDTNRSTYDVFHLSFRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPTGEALWEY
Protein: Predicted GTPase with uncharacterized domain, ortholog of T.maritima (4980952) (Q97IJ0)
Organism: Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)
Interaction partners:
- Biotin synthase family enzyme
- Thiamine biosynthesis enzyme ThiH
- Uncharacterized protein, ortholog of Thermotoga maritima
- ATP-dependent Clp proteinase
- Hydrogene dehydrogenase
- aspartate ammonia-lyase
- Thiamine biosynthesis enzyme, thiH
- Hydrogenase expression-formation factor
- Hydrogenase formation factor
- Phosphoheptose isomerase
Sequence:
MNELNSTPKGERLHIALFGKTNVGKSSVINALTSQEIALVSNVKGTTTDPVYKAMELLPLGPVMLIDTAGLDDISDLGELRRGKTLEVLSKTDVAILVFDVESGITEYDKNIYSLLLEKKIPLIGVLNKIDKKDYKLEDYTSQFKIPIVPISALNNKGINNLKDELIRLAPENDDKFKIVGDLLSPGDIAVLVTPIDKAAPKGRLILPQQQTIRDILESDAIAMVTKEFELRETLDSLRKKPKIVITDSQVFLKVAADTPKDILMTSFSILMARHKGDLIELARGARAIEDLKDGDKILIAEACTHHRQSDDIGKVKIPRWLRQKTGKKLEFDFSSGFSFPPNIEDYALIVHCAGCMLNRRSMLHRIESSVKKQIPIVNYGVLIAYVQGILPRALKPFPYADRIFNQSSRN
Protein: Glucagon a (A0A0R4IS85)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKGVQYFASLLLLLFVHKCICVPLQGDSTSTETADSFLARAPGLTTMKRHSEGTFSNDYSKYLETRRAQDFVQWLMNAKRNGGSVKRHAEGTYTSDVSSYLQDQAAQSFVAWLKSGQPKPDVANNKGANMAQRRHVDGSFTSDVNKVLDSIAAKEYLQWVMNSKASGTSGKRGGNQ
Protein: Vang-like protein 2-A (Protein strabismus-A) (Van Gogh-like protein 2-A) (Xstrabismus-A) (Xstbm-A) (Q90X64)
Organism: Xenopus laevis (African clawed frog)
Function: Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruit dvl/dsh and prickle from the cytoplasm to the plasma membrane. Acts in a PCP complex to regulate the polarized assembly of fibronectrin on the surface of the mesoderm during gastrulation. Regulates convergent extension cell movements in both dorsal mesoderm and neural tissue during gastrulation, without affecting cell fate. Regulates neural fold closure during neurulation. May be required for cell surface localization of fzd3 and fzd6 in the inner ear (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:11780127, ECO:0000269|PubMed:12941693}; Multi-pass membrane protein {ECO:0000269|PubMed:11780127, ECO:0000269|PubMed:12941693}. Note=Cell membrane localization is regulated by prickle. {ECO:0000269|PubMed:11780127, ECO:0000269|PubMed:12941693}.
Interaction partners:
Sequence:
MDNDSQYSGYSYKSGHSRSSRKHRDRRERHRSKSREGSRGDKSVTIQAPGEPLLDNESTRGEDRDDNWGETTTVVTGTSEHSISHDDITRITKDMEDSAKLDCSRHLGVVIGGALALLSFLTPIAFMLLPQILWREDLEQCGTACEGLFISVAFKLLILLLGSWALFFRRPKAFFPRVFVFRALLMVLVFLLVVSYWLFYGVRILESRDKNYQGIVQYAVSLVDALLFVHYLAVVLLELRQLQPQFTIKVVRSTDGASRFYNIGHLSIQRVAVWILENYYHDFPVYNPALLNLPKSILSKKMSGFKVYSLGEENTTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRKARLVVAVEEAFTHIKRLQDEDQKNPREIMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILHHLEFCITHDMTPKAFLERYLGPGPTIQYHKDRWLAKQWTLVSEEPVTNGLKDGVVFVLKRQDFSLVVSTKKIPFFKLSEEFVDPKSHKFVMRLQSETSV
Protein: RNA polymerase-associated protein CTR9 (Centromere-binding factor 1-dependent protein 1) (Cln three-requiring protein 9) (P89105)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II. Also has a role in transcription-coupled histone modification. Required for activation of RAD6 ubiquitin conjugate and the BRE1 ubiquitin ligase which ubiquitinate 'Lys-126' histone H2B. Activates the SET1 histone methyltransferase complex for methylation of 'Lys-4' of histone H3 and for methylation of 'Lys-73' of histone H3 by DOT1 and 'Lys-36' of histone H3 by SET2. In complex with PAF1, required for normal CLN1 and CLN2 G1 cyclin expression in late G1. Also has a role in chromosome segregation where it appears to be involved in microtubule placement.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:10219085, ECO:0000269|PubMed:15643076}.
Interaction partners:
- RNA polymerase-associated protein LEO1
- RNA polymerase-associated protein RTF1
- Antiviral protein SKI8
- FACT complex subunit POB3
- FACT complex subunit SPT16
- Transcription elongation factor SPT5
- RNA polymerase II-associated protein 1
- Cell division control protein 73
- Transcription elongation factor SPT6
- DNA-directed RNA polymerase II subunit RPB1
Sequence:
MTNAMKVEGYPSMEWPTSLDIPLKASEELVGIDLETDLPDDPTDLKTLLVEENSEKEHWLTIALAYCNHGKTNEGIKLIEMALDVFQNSERASLHTFLTWAHLNLAKGQSLSVETKEHELTQAELNLKDAIGFDPTWIGNMLATVELYYQRGHYDKALETSDLFVKSIHAEDHRSGRQSKPNCLFLLLRAKLLYQKKNYMASLKIFQELLVINPVLQPDPRIGIGLCFWQLKDSKMAIKSWQRALQLNPKNTSASILVLLGEFRESFTNSTNDKTFKEAFTKALSDLNNIFSENQHNPVLLTLLQTYYYFKGDYQTVLDIYHHRILKMSPMIAKIVLSESSFWCGRAHYALGDYRKSFIMFQESLKKNEDNLLAKLGLGQTQIKNNLLEESIITFENLYKTNESLQELNYILGMLYAGKAFDAKTAKNTSAKEQSNLNEKALKYLERYLKLTLATKNQLVISRAYLVISQLYELQNQYKTSLDYLSKALEEMEFIKKEIPLEVLNNLACYHFINGDFIKADDLFKQAKAKVSDKDESVNITLEYNIARTNEKNDCEKSESIYSQVTSLHPAYIAARIRNLYLKFAQSKIEDSDMSTEMNKLLDLNKSDLEIRSFYGWYLKNSKERKNNEKSTTHNKETLVKYNSHDAYALISLANLYVTIARDGKKSRNPKEQEKSKHSYLKAIQLYQKVLQVDPFNIFAAQGLAIIFAESKRLGPALEILRKVRDSLDNEDVQLNLAHCYLEMREYGKAIENYELVLKKFDNEKTRPHILNLLGRAWYARAIKERSVNFYQKALENAKTALDLFVKESSKSKFIHSVKFNIALLHFQIAETLRRSNPKFRTVQQIKDSLEGLKEGLELFRELNDLKEFNMIPKEELEQRIQLGETTMKSALERSLNEQEEFEKEQSAKIDEARKILEENELKEQGWMKQEEEARRLKLEKQAEEYRKLQDEAQKLIQEREAMAISEHNVKDDSDLSDKDNEYDEEKPRQKRKRSTKTKNSGESKRRKAAKKTLSDSDEDDDDVVKKPSHNKGKKSQLSNEFIEDSDEEEAQMSGSEQNKNDDNDENNDNDDNDGLF
Protein: Protein broad-minded (TBC1 domain family member 32) (Q3URV1)
Organism: Mus musculus (Mouse)
Function: Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20159594}. Cell projection, cilium {ECO:0000269|PubMed:20159594}.
Interaction partners:
- Cilia- and flagella-associated protein 20
- WD repeat-containing and planar cell polarity effector protein fritz homolog
- Sodium channel and clathrin linker 1
- Ubiquitin-conjugating enzyme E2 variant 3
Sequence:
MAHFSSEDEVMLQAMLRQLFQSVKEKITGAPSLECAEEILLRLEETDENFHNYEFVKYLRQHICNMLGSMIEEEMEKCTSDQNQGEDSGYDTVVQHVTKRTQESKEYKEMMHSLKNIMMVVVEAMINKFEEDETRSEDRQRKMQSGSCCTDNCSDSDSSFNQSYKFCQGKLRLILDQLDPGQPKEVRYEALQTLCSAPPSDVLSCENWTTLCEKLTTSLSDPDPMFTDRILKFYAQTFTLSPLHMTKEIYTSLAKYLEVYFLSRENHLPTLSTGVDITSPNVTRLLKKVRLLNEYQKEAPSFWIRHPEKYMEEIVESTLSLLSVKHEQSHLVPQKILDPIYFFALVDTKAVWFKKWMHAYYSRTAVLRLLEKKYKCLITTAVQQCVQYLELCEAMKADEILRHPKHCGTKQKSFYYSGQELQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRKDSVSLTNLLVLFTQLIYYSPSCPKMTSIMCSENYSPASMVTDVLRMLCDQKECAVECLYNSTVTEALLLPIHNLTKGTAAAPDCSETALIHIADILARIASVEEGLILLLYGENMNSSEEESLTGAHIIAKFSKKLLEEDISIFSGSEMLPVVKGAFISVCRQIYGTCEGLQVLLPYGLHESIAKAWKKTSLLSERIPTPVEGSDSVSSVSQVSPNSVAWEDNLLDDLLNFAATPKGLLLLQRTGAINECVTFMLSQYAKKPQVNRQKKFGYEVLVVQVASTAAGAVALQNSGFISALITELWSNLECGRDDVRLTHPRATPVDPIDRSCQKSFLALVNLLSYPAVYELTANQELPNKAEYSLREVPTCIIDIMDRLIVLNSEAKIRSLLNYEQSHTFGLRLLSVVCCDLDALLLLEAQYQVSNMLLHAQEENTFEISENHRNFIIDGLSVERNHVLVRINLIGGPSERILPPRMLEKGDDPYPWPMFSSYPLPHCYQSEGPRSADLKQDNDIGNLLSCFKMSDKQTEWIENCRRQFCKTMKSKPDAVHGSALGELLEKFVLLLTENPSECYFPSVEYTATDANVKNESLSSVQQLGMKMTVRYGRFLNLLKDGAENELALVLKHCEKFLKQQQSPVTSSLLCLQGNYAGHDWFVSSLFMIMLGDKGKTFHFLQHFSRLLTSAFLWVPRLHNSRYLPVDTLGTGIHPIYFCSAHYIEMLLKAEVPLVFSAFHMSGFAPSQICLQWITQCFWNYLDWIEICHYIATCVVLGPDYQVYVCIAVLKHLQRDILQHTQTQDLQVFLKEEALHGFRVSNYFEYMENLEQNYRPVLLRDMRSIRVQNT
Protein: RNA helicase (EC 3.6.4.13) (A0A2R8Y4A4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGSGYGGFYNSDGYGGNYNSQGVDWWGN