wanglab/gogpt-training-data huggingface dataset:
Protein: Glucose N-acetyltransferase 1 (EC 2.4.1.-) (N-acetylglucosaminyltransferase) (Q12096)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Vacuole membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- LSM complex subunit LSM5
- Uncharacterized protein YIL102C-A
- LSM complex subunit LSM6
Sequence:
MRLISKRRIRFIVFILFGVLTVFVVSRLVVHFQYNQEIKFYKKYFQQRKDGLHEIYNPLEIKQIPKETIDDLYTARLDKELKNGEVIEWSKFAYVNYVTNADYLCNTLIIFNDLKQEFETKAKLVLLISKDLLDPNTSSNVAYISSLLNKIQAIDEDQVVIKLIDNIVKPKDTTPWNESLTKLLVFNQTEFDRVIYLDNDAILRSSLDELFFLPNYIKFAAPLTYWFLSNSDLEKSYHETRHREKQPINLQSYTKVLTKRIGKGQMIYNHLPSLPHSLYLNSNNIAQDIISSTSSLSPLFDFQSSKKVGKLKFASNLMVINPSKEAFDEIVNVMLPKILNKKEKYDMDLINEEMYNLKKIIYKQFIFFRKVRKLFKPEVLVLPFARYGLLTGSLRNPRHYSIIYNDVLGYKTLDNDGNDIPVGLNDSVAYSKYIHFSDYPLAKPWNYPSMKEFECIVKEEDAEDSKLEHQACDLWNSVYASYIQSREICLV
Protein: Alpha-mannosidase (EC 3.2.1.-) (Q9VF33)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Alpha-mannosidase 2
- alpha-1,2-Mannosidase
- Mannosyl-oligosaccharide alpha-1,2-mannosidase IA
- alpha-1,2-Mannosidase
- Alpha-
- Probable beta-hexosaminidase fdl
Sequence:
MSFKLFRRGSARCIGLLSAFVTILLCLYYISIGQPNPTPISETGAPSAALRGSPLSGLTGFSVDGGSSSIIHQQKQQLVIASNQKKSSETKSAQTSVSPEEQSEEQYTNSNWGDKCYELIQSNTNITASEEHSKFDFQPEWMRSKEYWDRGFEERFDAQKKDKQRPPLKIIVVPHSHNDPGWLKTFTNYFQSDSRQILNLLVTKMQEYTDMTFIWSEISFLQLWWDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNVTPKVGWSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDKDSEAGSLLTHNMPFDIYSIKGSCGPHPFICLNFDFRKIPGEYTEYSVKAQFITDDNLESKAQLLLEQYARTASLFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHIMANRRLYNADIRFGTPSDYFEAIKERMKDHTPGFPTFKGDFFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIVFTLAYNTARQAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFESTQNMVKMQESCLELLLQKGQPRHHGFLLSEFERDNFNKLPRKMPIQMANGDESTPTVPAGEGGAGGSSSSGSVGSFVLYNSLAQKRLEVVTLRVQHPNVKIVNDKGVELNHIQINPVWNITDTYEQGLGTSVSGTVGRIRTSTRQFEVMFVAELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTESQPASVSPPEEIESSPTSVFEARGKPAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELLKPLQCNIKFAAYRSAQFHSGAYLFKTDPEQSEAEKEVLEGYTDMRIIITSGPIASDVTVIYGPFLAHTVRIFNTRTHLDAAIYVENDIDFEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKEPVDAATMPELPVFYSDQNGFQYHERIKVPAIGIEGNYFPITSGAFIQDSRLRLTLLTTHAQGAASYEPGQLEVMLDRRTLYDDYRGMGEGVVDSRLTRHKFWLLVEDLPGGQHVTQPPSYKVLSQQAQQLANALRYPPNLYFVSNLEQPELAAALLPLVRLLPKGPLPCDVHLTTLRTLSDPELQLFPSASALLVLHRQGFDCSVSAGRELSMEAICPLSSKGLGNVQLGRLSLHTIEATSLTGTEQKSSRESYHIRSLAEISLEPMELRTFNLTFRSEV
Protein: Pentatricopeptide repeat-containing protein At1g11290, chloroplastic (Protein CHLORORESPIRATORY REDUCTION 22) (Q3E6Q1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in multiple sites RNA editing events in chloroplasts. Involved in the editing of the site 7 of ndhB (ndhB-7) and site 5 of ndhD (ndhD-5) transcripts, which are two plastid-encoded subunits of the chloroplast NAD(P)H dehydrogenase (NDH) complex. Involved in the editing of the site 3 of rpoB (rpoB-3) transcript. Required for the activity of the NDH complex of the photosynthetic electron transport chain. Possesses low endoribonuclease activity in vitro.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Protein PROTON GRADIENT REGULATION 5
- NAD
- Phosphoglycerate mutase family protein
- NAD
- RNA-binding
- KH domain-containing protein At3g08620
Sequence:
MSSQLVQFSTVPQIPNPPSRHRHFLSERNYIPANVYEHPAALLLERCSSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSKKIYAFLEKLICHIKEAGYVPDTNLVLGVENDVKEQLLSTHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIVVRDMQRFHHFKNGACSCGDYW
Protein: At3g29270 (RING/U-box superfamily protein) (Q84JZ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Putative F-box protein At3g25750
- F-box protein At3g54460
- E3 ubiquitin-protein ligase RMA
- F-box protein SKIP5
- Probable E3 ubiquitin-protein ligase WAVH2
- SBP family protein
- E3 ubiquitin-protein ligase CSU1
- E3 ubiquitin-protein ligase RFI2
- Probable E3 ubiquitin-protein ligase RHA1A
Sequence:
MLSIPDTRMWNLASSYLTGNIGPKNDIRRPVHAHAECSDDDVSSVGSKDEGLECPICWESFNIVENVPYVLWCGHTMCKNCILGLQWAIVKLPTHPVQLPLFISCPWCNLLSFRLVFRGTLRFPHKNYFVLWMVERMNGERRNSPGGAQTDGNNDHTRETPSPCLHNRHHRSQPEPSRSVNDHRIPRDNIQTSLRKSLVFFVQLTAKFPLVVIFLLIILYAIPTSAAILAMYILVTLLLALPSFLILYFAYPCLDWLVREIVT
Protein: NLR family pyrin domain containing 2 (K7EMK2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLHLNAVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERSQDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPADAHRNLCLALRGHKTVTYLTLQGNDQDDMFPALCEVLRHPECNLRYLGYIS
Protein: Photosynthetic apparatus regulatory protein RegA-1 (D5AKG8)
Organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Interaction partners:
- histidine kinase
- histidine kinase
- Photosynthetic apparatus regulatory protein RegA-2
- Protein SenC
Sequence:
MAEEEFAELGSDRSLLLVDDDNAFLTRLARAMEKRGFQTEIAETVSAGKAIVQNRAPAYAVIDLRLEDGNGLEVVEALRERRPEARIVVLTGYGAIATAVAAVKMGATDYLSKPADANDITNALLAKGEALPPPPENPMSADRVRWEHIQRVYELCDRNVSETARRLNMHRRTLQRILAKRSPR
Protein: UPF0761 membrane protein YihY (P0A8K8)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- Alpha-D-glucose 1-phosphate phosphatase YihX
- Uncharacterized transcriptional regulator YjhU
- D-aminoacyl-tRNA deacylase
- Probable acyltransferase FabY
- UPF0162 protein YchA
Sequence:
MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
Protein: Large ribosomal subunit protein uL1 (Q9VFE0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Large ribosomal subunit protein eL20
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL6
- 40S ribosomal protein S24
- GEO07453p1
- Large ribosomal subunit protein uL22
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein eS25
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein eL38
Sequence:
MVSKVSRDTIYVAVKNILLNSQAKGPDCLETVELQIGLRDYDPDKCKRFHGSVLLHHLAVPQLKVCVFGDQEHCYKAKAIGVDCLDVEALKKLNKDPKLTKKLSKAYDVFLASESIIKQIPRLLGPGLTNAGKFLTPLARGESMSSKIKILSTKKKHMKRMECLSVNVGHVGMHPEELARNIAISINFLVSLLKDNWQNVRSLHIKSSLGVPHQLY
Protein: TEF transcription factor, PAR bZIP family member a (Thyrotroph embryonic factor beta) (O57673)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSSEIPEIFKALLEYPFSLPSIDDNENDKEKLFESVESGGVSEMGPSAALTPAIWEKTIPYDGDTFHLEYMDLEEFLMENGIAAAENEQKSSEKENIQLTAEEPSTASAVKTAPAVTLLPVMALDPCEEEVVTITTSSSSSADNKSEENRMTPDPINPDEIEVDVNFEPDPTDLVLSSIPGGELFDPRKHRFSEEELKPQPMIKKAKKVFVPEDQKDDKYWQRRKKNNVAAKRSRDARRLKENQITVRAAFLERENSALRQEVAELRKDFGRCKNTVARYEAKYGALGPEEDV
Protein: Histone deacetylase 6, isoform G (EC 3.5.1.98) (M9PJN5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Paired amphipathic helix protein Sin3a
- Histone deacetylase HDAC1
- Chromodomain-helicase-DNA-binding protein 3
- Methyl-CpG binding domain protein-like, isoform C
- Transitional endoplasmic reticulum ATPase TER94
- Histone deacetylase complex subunit SAP30 homolog
- Chromodomain-helicase-DNA-binding protein Mi-2 homolog
- NAD-dependent histone deacetylase sirtuin-1
- CoRest, isoform G
- Cortactin, isoform A
Sequence:
MSPPIVTRRSAQQAKIQTRAMASKSKTGTTGAATAAGGTGSSSGSISGGFNAADPRKSNKPNAALLEAKRRARNNMLKNQGCGSQESVTDIFQNAVNSKSLVRKPTALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRHWIGGPPPMDRYPTRDTAIPLPPEKLTSNAARLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEPMAWTHGCAWREDGCYATGPDGRDEDDDDDNGAGSSICLRLERNNXPLAIRVLDALTDYLCALCPPLRHLIHFLAEHLWPLLERIYLNLLHYFLAH
Protein: RH35990p (Q8IGE9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
DPCSRGAGARFSHFLAQPIEPTKRSLRVQTWKKIQEGKVGIGFNNIFNRIPSFVGADKAAALFANEEEFKKAQHIKVNIDRVLHEFKELALLADKSVYLPSTRESSALCLKVDVLADATEEQKKEALRVQDIQKFRSEIGLDSGLKLDIVVIGSVVVSREGYRIGRGNGFADLDIGLLIELGAITPKTIIVTIVHDMQVVDSLPPNLFQKYDTPVDIIATPTEIIRVPKRLSFPNGVYWELLSERRLKILPVLQQLKEREEKAGKSISLKEEDTDVEQHQNNRRRRGPVRRRIQRGNPGRTTSQTDNEQPQGETAQKRTPRRKGRFVNRRRRTTKSEGDQSGVEAGAKTDDRKLPEAGTDERRSKKNKNSDFCIKLTNLSRDIRVKDLKSELRKRECTPMSISWKGHFGKCFLHFGNRKGVPSTQDDMDKVLKSLNDLSLTITTGGETAPAAAAGEGGEKAESAETATPVQTKTILVNVELIQFGEKKSASSTGANAGAGEDGKADAQNGGEAVTVAGGDVGGARIEAVDTTTV
Protein: ABC1 family protein (F4KIJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS9x
- Probable disease resistance protein At1g62630
- Uncharacterized protein At5g13720)
- Probable disease resistance protein At1g59620
- Probable disease resistance protein At1g12290
- Disease resistance RPP8-like protein 3
Sequence:
MRNSRFRGINSGSFQNKRWWSLVLDSLLSFFVRLSEIIKRFFHKFVSMGLGNIYRRRMKVFSIAILIYLDYKGVQQKEKWIKKSKVPALWDKAHDRNAKRVLNLIVELEGLWVKLGQYLSTRADVLPQAYISLLTQLQDSLPPRPLQEVCKIYLNVNIRGYTKKEKYFFDIMSMWYDFKVCRTIERELGNSMDVLFTDFVDEPLATASIAQVHRATLANGQDVVVKVQHDGIRAIILEDLKNAKSIVDWIAWAEPQYNFNPMIDEWCKEAPRELDFNIEAENTRTVSGNLGCKKTNDEVRSANRVDVLIPDIIQSSESVLILEYMDGVRLNDVESLDAFGVDKQKIVEEITRAYAHQIFVDGFFNGDPHPGNFLVSKEPQHRPILLDFGLSKKISHSLKQALAKMFLASAEGDQVALLSAFAEMGLKLRLDMPDQAMSVAGLFFRSSTPSSEAMKTFKTLNDQRVQNMKVIQEKMQLNQKEVKRFNPIDAFPGDIVIFARVINLLRGLSSTMNVRIVYLDIMRPFAESVLLGSISRGPTVDAHWIHDSPIHSDVESKVRKLLAELGSIQKILGIQVCAYKDGKVIIDTAAGVLGRYDPRPVQPDSLFPVFSVTKGVTAGMIHWLVDKRKLQLDQTVANMWPGFGSNGKDTIKVHHVLNHTSGMQNSFDPVGENPLLICDWDECLKRIANSSPETEPGSQQSYHYLTFGWLCGGILEYASGKKLQEILEESIVKPLNIDGELYIGIPPGVESRLATLTFDTDEMSKLSSIASQPELPSTFQPDKIIQMATNLPVLFNTLNVRRAIIPAANGHCSARALARYYATLADGGLVPPPHSSLSQPPLGSHTHVPKFTSLKDTTKKKKGKEMAATEKGKSKDHQERKLYDEKQFMSASSSRESNTESLARLVDTNSSAGKTEINSDDHQHDIHNMFSNPRIHDAFMGAGDYSGLVVPDGKFGLGFKRAISQDGSLVGFGHSGLGGSTGFCDINNRFSIAVTLNKMSMGGVTANIVKLVCSELNIPLPKDFATDIGADSQMGTPLIN
Protein: Dye-decolorizing peroxidase (DypB) (EC 1.11.1.-) (C0ZVK5)
Organism: Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Function: Cargo protein of a type 1 encapsulin nanocompartment. Has both general peroxidase activity and dye-decolorizing activity. Can catalyze the oxidation of both protoporphyrinogen IX and coproporphyrinogen III to their corresponding porphyrins. Also efficiently decolorizes the dyes alizarin red and Cibacron blue F3GA (By similarity). This cargo-loaded encapsulin nanocompartment is probably involved in protection against oxidative damage (By similarity).
Subcellular location: Encapsulin nanocompartment {ECO:0000269|PubMed:24981030}.
Interaction partners:
Sequence:
MALPAIPQPLLTPLTEAAIFLVFTIDEGGEQAVHDVLADISGLQRSIGFRVPAGGLAAVVGIGSDAWDRLFEGPRPAELHPFVELTGDKHHAPRTPGDLLFHIRARQMDLCFEFATVVTNRLAGAASVIDEVHGFKYFEQRDLMGFVDGTENPSGQAAYVAVTVGDEDPDFAGSSYVIVQKYLHDMSEWNSLPVEEQENVIGRSKLEDLEMDDDTKPANSHTALTVIEDESGEQIQILRDNMPFGHVGSAEMGTYFIGYSASPTVTEQMLTNMFIGNPVGNYDRILDFSTAVTGINFFVPTADFLDDPPDAPTRLVPEATFTAPISDGSLGIGSLKRSAQQ
Protein: At1g68160 (ZZ-type zinc finger protein, putative (DUF3755)) (Q8GZ67)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MWMATQSNSGFDSLSSMMSRHAINFQSNTSSEMTPMSPYLGMNMNMINVGSPGFLQTGNSSNGSDSGSGLKLDTSMVSEWSNEEQYILDAGLEKYKDMPSIDMYIQIGNTLPDKSIRDIALRCRWLRRKRRKSEELNCGRRASSSKGKQVESSSKSSIPSVLPHNMASYPFSGPSTSTSKQITSEDLSSYATNLIEQNVRAFSQIRANLSSYKAGDNLDLFRQARNNLITIQNEINNMPGLMNKMPPLPVTINDDLSVMMPFNTMQSGGFHRK
Protein: Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Glycine-rich beta glycoprotein) (GBG) (PBF2) (Properdin factor B) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment] (P00751)
Organism: Homo sapiens (Human)
Function: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Subcellular location: Secreted.
Interaction partners:
- Complement C3
- Complement factor D
- Properdin
- Complement C4-A
- Complement factor I
- Complement factor H
- Complement C4-B
- Complement factor H-related protein 3
- Complement factor H-related protein 1
- Complement C2
Sequence:
MGSNLSPQLCLMPFILGLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKVASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQAVYSMMSWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLGFL
Protein: RNA polymerase sigma factor RpoD (Sigma-70) (P00579)
Organism: Escherichia coli (strain K12)
Function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. Preferentially transcribes genes associated with fast growth, such as ribosomal operons, other protein-synthesis related genes, rRNA- and tRNA-encoding genes and prfB.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00963}.
Interaction partners:
- DNA-binding transcriptional dual regulator CRP
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta'
- DNA-directed RNA polymerase subunit omega
- DNA-directed RNA polymerase subunit beta
- Regulator of sigma D
- RNA polymerase-binding transcription factor DksA
- DNA primase
- Transcription termination/antitermination protein NusA
- ECF RNA polymerase sigma-E factor
Sequence:
MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDIIQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAREKFAELRAQYVVTRDTIKAKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD
Protein: Fibronectin leucine-rich transmembrane protein 1b (Leucine-rich repeat transmembrane protein FLRT1) (F1QF54)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MATESLVELRDWLFLLLLCLTLLVEVLEFAAATAAAAEAALGEAELQGEVPCPSACRCDDGFIYCNDRGLTLIPPLPLTAAVLYLQNNRIDNAGLPTSLERRLTVRVVYLYDNELDDFPTHLPPSLRELHLQDNNIRTLPRSALARLPLLEKLHMDDNSISTVSIEDKAFTNNPRLRLLFLSRNHLSSIPSGLPASLEELRLDDNRISTIPTHAFRGLSSLRRLFLDGNLLANQRIADDTFSRLSNLTELSLVRNSLQAPPLNLPSLHLLRLYLQDNAIAHMPRGSLDGMRRLQKLDISGNNLTTLPRGLFKDLDSLSQLLVRGNPWYCGCNLRWLHDWLHERGSSVTVRGLTCHAPERLRGMALRDLSSQLEDCEVTVDAAGGMVGNEVAKKEKGYFPTQPPATTTPPLPQGSLFTLRSRRPGHKYSDMGQDSLGGGNGFVSKSLLISVKPLTPETVHITWQAAQPVPSFRLSWLRLGNSPAMGSITETLVPGDRREYLLTQLQPQSSYIICLVPLAGNDGKRTSFTATGGLNINTNSEHEHPACAKTETDPLEQPMSDQDSDRGTDALSALPLAGIIGGATALVSLFLIFGIFCWYGHRAGYLAPGDHSIYGRDVVGSRDASKHYDDYVESGTIKDTSILEIRAHGFQMTPMSAQQPLQPKAKVEDMTYIHTIFPSNNATLYRSTLNHTGNPSYGTNRGYREGGIPDIDYSYT
Protein: Zinc finger protein 277 (E9Q6D6)
Organism: Mus musculus (Mouse)
Function: Probable transcription factor. Involved in modulation of cellular senescence; represses transcription of the tumor suppressor gene INK4A/ARF, perhaps acting via the Polycomb group (PcG) complex PRC1.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9NRM2}. Cytoplasm {ECO:0000250|UniProtKB:Q9NRM2}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9NRM2}. Chromosome {ECO:0000269|PubMed:20808772}. Note=Probably localized to nucleolus and cytoplasm in complex with 40S ribosomal protein S2/RPS2. {ECO:0000250|UniProtKB:Q9NRM2}.
Interaction partners:
Sequence:
MAASEVQGLPVDPREAGVRGVRGGIGHTDHEGHLGSFQLLATINKAAMNIVEHVSFLPVGTSSGYIAASSGITMSNFLRNRQTDFQSGCTSLQSHQQWRSVPLSPHPHQHLLSPEFLILAILTGVRWNLRIALICISLMIKDAEHFFRCFSAIWYSSDSKDCILEPLSLPESPGGTTALEGSPSVPCIFCEEHFPMAEQDKLLKHMIIEHKIVIADVKLVADFRRYILYWRKRFTEQPITDFCSVIRINSTAPFEEQDNYYLLCDALPEDRILREELQKHKLKEVLDQQQRERNDTSFHGVCMFCSEEFRGNRSVLLNHMAREHAFNIGLPDNIVNCAEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNREYDRFYVINYLELGKSWEEVQSEDDRELLDLQEDDWSDWQEYPVSAVCLFCEKQEETIDKLYVHMKDTHEFDLLRIKSELGLNFYQQVKLVNFIRRQVHQCKCYSCHVKFKSKADLRTHMEDTKHTSLLPDRKTWDQLEYYFPTYENDTLLCTLSDSESDLTAQEQTENVPVISEDTSRLCALKQSSVLNQLLLQGCLEN
Protein: SEC12-like protein 1 (Protein PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR 1) (PHF-1) (Q8GYE0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in Pi uptake by facilitating the trafficking of PHT1-1/PHT1;1 from the endoplasmic reticulum to the plasma membrane.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16284308}; Single-pass membrane protein {ECO:0000269|PubMed:16284308}.
Interaction partners:
- small monomeric GTPase
- small monomeric GTPase
- Ras-related small GTP-binding family protein
- Small COPII coat GTPase SAR1A
- Small COPII coat GTPase SAR1B
- Inorganic phosphate transporter 1-1
- SEC12-like protein 2
- SEC12-like protein
- Inorganic phosphate transporter 1-4
- Probable ubiquitin-conjugating enzyme E2 24
Sequence:
MEIEEASRESGHVVCGSWIRRPKKVNWVLIAKASKRRGSSVSSPALLNIFSFDPITASLSSSPLATHTLKDSDGDPVAVSVHPGGDYFVCSTSKGGCKLFELVGGATGITILAKELLPLQNAGLQKCMAFSFDGSKLAVGGVDGCLRIMEWPNLSVILDEPKAHKSIRDMDFSLDSEFLATTSTDGSARIWKAEDGFPLSTLERSGDENIELCRFSKDGTKPFLFCAAQRGDTPMVNVYDISTWKKLGFKKLSRKTASTMAVSLDGKYIALGGKDGDVSVAEVKTMEIYHYSKRLHLGQSIASLEFCPSERVMLTTSSEWGEMVTKLTVPKEWKEWQIYALLFCLFMASVIAAYVFFENSDSFWKLPMGKDQKRPKISLFGGSSSTPSEDHSRWNLDL
Protein: Transmembrane protein 80 (Q96HE8)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9D3H0}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250|UniProtKB:Q9D3H0}.
Interaction partners:
- Transmembrane protein 231
- B9 domain-containing protein 1
Sequence:
MAAPRRGRGSSTVLSSVPLQMLFYLSGTYYALYFLATLLMITYKSQVFSYPHRYLVLDLALLFLMGILEAVRLYLGTRGNLTEAERPLAASLALTAGTALLSAHFLLWQALVLWADWALSATLLALHGLEAVLQVVAIAAFTR
Protein: Down syndrome cell adhesion molecule 1, isoform BT (A0A0B4K7I5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVSQHYEEDIHKAFVIRGNSAILKCDIPSFVADFVNVISWHSDEKENFYPGTEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIGSVSPKISNSDDLKHVKVKRLLSLSLLCPAQAYPQPISRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPKITPFTFGEDPTNVEDSVSVTCLISSGDLPIDIEWLFNDFGISSYSGMTVLRGGKRTSMLTIDNVHARHAGKYSCRAKNHAAAVNYTTELIVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV