wanglab/gogpt-training-data huggingface dataset:
Protein: Homeobox-leucine zipper protein HDG9 (HD-ZIP protein HDG9) (Homeodomain GLABRA 2-like protein 9) (Homeodomain transcription factor HDG9) (Protein HOMEODOMAIN GLABROUS 9) (Q9FFI0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that binds to the DNA sequence 5'-GCATTAAATGCGCA-3'.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeodomain-like superfamily protein
- MADS-box transcription factor PHERES 1
- Lysine-specific demethylase JMJ28
- Transcription factor MYB3R-2
- Maternally expressed PAB C-terminal protein
- Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2
- Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH7
- Formin-like protein 5
- E3 ubiquitin-protein ligase ORTHRUS-LIKE 1
Sequence:
MDFTRDDNSSDERENDVDANTNNRHEKKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAKSHNEKADNAALRAENIKIRRENESMEDALNNVVCPPCGGRGPGREDQLRHLQKLRAQNAYLKDEYERVSNYLKQYGGHSMHNVEATPYLHGPSNHASTSKNRPALYGTSSNRLPEPSSIFRGPYTRGNMNTTAPPQPRKPLEMQNFQPLSQLEKIAMLEAAEKAVSEVLSLIQMDDTMWKKSSIDDRLVIDPGLYEKYFTKTNTNGRPESSKDVVVVQMDAGNLIDIFLTAEKWARLFPTIVNEAKTIHVLDSVDHRGKTFSRVIYEQLHILSPLVPPREFMILRTCQQIEDNVWMIADVSCHLPNIEFDLSFPICTKRPSGVLIQALPHGFSKVTWIEHVVVNDNRVRPHKLYRDLLYGGFGYGARRWTVTLERTCERLIFSTSVPALPNNDNPGVVQTIRGRNSVMHLGERMLRNFAWMMKMVNKLDFSPQSETNNSGIRIGVRINNEAGQPPGLIVCAGSSLSLPLPPVQVYDFLKNLEVRHQWDVLCHGNPATEAARFVTGSNPRNTVSFLEPSIRDINTKLMILQDSFKDALGGMVAYAPMDLNTACAAISGDIDPTTIPILPSGFMISRDGRPSEGEAEGGSYTLLTVAFQILVSGPSYSPDTNLEVSATTVNTLISSTVQRIKAMLKCE
Protein: Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5) (Protein four way stop) (Q9VJD3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for normal Golgi function and necessary during spermatogenesis. Required for cleavage furrow ingression during cytokinesis in dividing spermatocytes and for the extensive polarized cell growth that accompanies spermatid elongation.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:12529436}; Peripheral membrane protein {ECO:0000269|PubMed:12529436}. Note=Localized to Golgi membrane throughout spermatogenesis, as seen in spermatocytes and differentiating spermatids.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 7
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 2
- Conserved oligomeric Golgi complex subunit 8
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar protein sorting-associated protein 53 homolog
- Syntaxin-5
Sequence:
MVTGDPVATKTPNAADSDDNDFTASMSHLTIGQQIQELSKQLQNTKEELHQQVRDKHGALLQQATHAGRFDAALNALAEDVQRVRETGHRLKNQVDTQYQQVENQTQVLGRLHDVSHLLRSAGTLLSLTAKLKATKDVLRLAEIHFELGQLIEDKELKDIDFIQQERAYVISSAQKIRNLTQMQLVTGLQERNENQVVNALKIFMNFNTLEKSLDNLLATFIADMEQSLKECFAGNDISVLNKSPTHNVSKPAPSRGPGKTPQLTTTQNFRAKFWKSLHWLLYDELFETCTQIKLLKTALEQINQFGYTSESSDQCIPQRFWQQVQQLLRKSFDECPQHVTQTLQEGLSKLLTSARGLEQRLHGEFQFDNELFAPLEVGYVSKCAANFKACLAGVDLPGNETVDNFIRVASTELSAALIDSRLTNAIANVFAACGKELCTKLEAQIKLGADSKQVVDLPNLQQQQNTQLANVLFYYKDSVRRMLSDLHVHFEKTPGTAREIISRSLEQADLLIGTILQQIMESIITTISIIVLSMHREPGLNSERMSTTGPSMYMKELQEFVNRSWSHHIALFDDKQMTKKCGHELAKRCIELFLHNVCILRPLSSCGRQRLKQDCQHMEQALKPLCPNLAELGKPSRLLRAMSLLIVQTAEELVKQTIGEDSLVPSYIVLLLLFGHAGADLQSPHTTANWSNERLIEWLDGHTAEREKLELISGALQRYRDNARRKNIQQYDEVYPMMVDYFEQALKALP
Protein: Pannexin (F1QSR7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU010713}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU010713}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
- Pannexin
- Caspase a
- Pannexin
- Ectonucleoside triphosphate diphosphohydrolase 1
- Ectonucleoside triphosphate diphosphohydrolase 8
- Ectonucleoside triphosphate diphosphohydrolase 3
- Gap junction protein
- Gap junction alpha-1 protein
- Caspase b,-like
- Calcium homeostasis modulator 1
Sequence:
MAIARVATEYVFSDFLLKEQSDSKYKGVRLELATDKLVSFIAVGLPLLLISLAFAQEVSVGTQITCFPPTNFTMRQAAYADSFCWAAVEHHPSENETYSAPLHLHKFFPYILLLLAILMYIPALFWRFTAAPSLSSDLSFIMEELDRCYNRAIRLAKSITTKQDKDIAEDPHSGLELTEACFKYPLVEQYLKTKRSSWALAAKYLLCRVLTFLTLLLGCFYLTYYIFWVSPSDQFSCHLRRGILVNQSEVPDVVQCKLVAVGVFRLLSCMNLVVYLLLVPAVVYAGLQPARQHQRGQFLRPYHLLPAFGHVLDLQPATRRYDDLSIYLLFLEENLSELKSYKCLQVLELLSEGGEAAFDTMCLLRTLGQVKTDMVDKRQAQTVNGNPEIVISEIKDVSVLLDDGVQADKSCSCVKDVRQRVV
Protein: N(Alpha)-acetyltransferase 15/16, isoform A (N(Alpha)-acetyltransferase 15/16, isoform B) (SD09860p) (Q9VWI2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Probable N-acetyltransferase san
- N-terminal amino-acid N
- N-alpha-acetyltransferase 20
- N-alpha-acetyltransferase 20
- N-alpha-acetyltransferase 30A
- GEO07882p1
- N
- N-alpha-acetyltransferase 35, NatC auxiliary subunit homolog
- Phagocyte signaling-impaired protein
- GEO02452p1
Sequence:
MPSSDPLPPKEGALFRKLLKCYELKQYKNGLKLAKQILSNPKYMEHGETLAMKGLTLNGLGRREEAYKYVRLGLRNDLRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWEKDNLQILKDLSLLQIQMRDLEGYKETRHHLFTLRPSQHASWIGFAMSYHLLGDYDMANSILETFSQSQTSIEAHDYRHSELLLYQNQILIESNRLQQAVDHLTKYQGQIVDKLAVRETMGDLYIKLQQQEKAVPIFESLIRRNPENVLYYEQYIAARQVTDSSAVVSIYRVFQEQYPRALCPRRLPLNIANGDEFRVVTDEYLRRGLRKGIPPLFVNVRTLHQIPERAAVIEELALQYFENLTRSGHFSREDADAGIPVEPASALVWTALFLAQHYDYMRDTDRALEYINVAIDHTPTLIELLITKGRIFKHAGDPVEAYVWLEEAQSMDTADRYINSKCAKYMLRANMVQEAEEICAKFTREGVSAMDNLNEMQCMWFQTECALAYQRMGRWGESLKKCHEVERHFAEIVEDQFDFHTYCMRKMTLRAYVGLLRLEDVLRQHPFYFKAAKCAIEVYIRLYDKPLKSETTIEEIDIENLPPSELKKLRSKQRKAKKKAELESAQAAQAQVKREQHQKSKQQANQETDPDAPQLDELVAEKLERTDDPLDKAIEFLKPLQQLAKERIETHLLAFELYYRKNKLLLMLQCIRRARAVDASHPVIHSCIIRFVKSLTSAAKEQPFNEHVQQVLEKATKELIGSKTPQQLNDEFIAKHNASILHLYEGARSLYELDNSKKAAAIKLVTSFNLAKLRLEEATKIYTALRDGDVFGECEAEAASYQQACHQRFQYARIFRNVEELEAQLQEKEAAKLRAEEEQQQLIHVDSSEPVSVLATAAAAS
Protein: Angiogenic factor with G patch and FHA domains 1 (Zgc:152959) (Q08CK9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MRAQGSRERARKTGGLNRLNVLSMAAEGKADLEAGDDGLESEIVSLRTQAEALREELKTCKDELQKLQKQLSQSERLQKTTESYNEDLRQQVDKLSAEIHERKKRDKEKVDAETQTEEYTWTETDYYNYYYGGYYQSETTAEQGTTAETQENVVKETQEASVYVEEQHPRIAETSVANPEQPNETSDIPQTEEASGEAGSIADMLRATAEEAMNQTNFVFDESSGMYYDHSTGFYYDSSSQLYYDANTGMYYYYDPESGKYQFHSRIEVPAALHPEVEQTPQRKTKDRKNRKSVKNTERASCPDGGGNKEVVLEIDKLSENHHRGKKDDAGSFKKGRKSRSRSPQRSRRTKSRDRSRKRSTNRKKTRRRSEDSDDSRCSRRKENGSNSEDKRKKTKKKRALRDRKSGSDEGSSESEPEEGEITESDGENHSCSVSSSSVSSIQKTLDSPDEEMEMETQMQEEAWPPCVRVTVVRSPVLQTGTLFILTADTVATIGREKDMNHAIRIPEMGVSKSHAEVYFDQDQQCYMLIDQGSQNGTVLNGNRILQPKVRCDPCPLTHGDELKMGETVLSFHIHAGTATCDGCEPGQIIAHLSRHKKDESSGAVLSKEDKEAQRQKELKMMKVKYGLKSSDYEEQKPLKNSKYKDRAENRRQTVGSEGKFQRDDAPASVHVEIGDENKGRQMLEKMGWKRGEGLGKDGAGIKDPIQLHMRKAQSGLGSSGSAMSVEDASLTKSKTQRNWERARERFSEACHTDSSHPENSQSPKAWVKSQETE
Protein: Inactive ubiquitin thioesterase OTULINL (Q9NUU6)
Organism: Homo sapiens (Human)
Function: Lacks deubiquitinase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31056421}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:31056421}; Peripheral membrane protein {ECO:0000269|PubMed:31056421}. Nucleus envelope {ECO:0000269|PubMed:31056421}.
Interaction partners:
Sequence:
MAATRSPTRARERERSGAPAAGSDQVHSWMLATSQALDTVWRMAKGFVMLAVSFLVAAICYFRRLHLYSGHKLKWWIGYLQRKFKRNLSVEAEVDLLSYCAREWKGETPRNKLMRKAYEELFWRHHIKCVRQVRRDNYDALRSVLFQIFSQGISFPSWMKEKDIVKLPEKLLFSQGCNWIQQYSFGPEKYTGSNVFGKLRKYVELLKTQWTEFNGIRDYHKRGSMCNTLFSDAILEYKLYEALKFIMLYQVTEVYEQMKTKKVIPSLFRLLFSRETSSDPLSFMMNHLNSVGDTCGLEQIDMFILGYSLEVKIKVFRLFKFNSRDFEVCYPEEPLRDWPEISLLTENDRHYHIPVF
Protein: MGT2 magnesium transporter (Q57XX8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MPCATKGEASPPVTTPVGRDGCLCVVTWQTAGRMSLQTCALESAADALVFLRNNLPGIALCGLWVDMQKCSEEEHRQVLQLLYPNMQPSHVEAVLANDMYDVVELQPTEGEYVVGCLSCSPSHGGPFPAATAMSRTELGCEEGVLCSFVCSERVLLTLHTAPFAGLAELFRHVLRDNSQWPMSMSAILCTLVCYTCELSLPDPTALIGEVDCIDEMMLLVAPGKRDQTDMLRRVALLRRHLSALNRKLQEKAKLISEMTGPAMRTTFVSRELHLGYMYREALEGLSQVLSRLECAQDTLDHANLNFMYAITMRMSQTSAGCDRQVMIVNKIATICLPAILVASLFGMNCKVQWVADDCDSLYPFWTIVALMIVWMAALLFQPVRDLIREKGG
Protein: Ubiquitin-like protein ATG12B (Autophagy-related protein 12b) (APG12-like protein b) (AtAPG12b) (Q9LVK3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. ATG12/ATG5 conjugate has an essential role in plant nutrient recycling.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Autophagy protein 5
- Ubiquitin-like modifier-activating enzyme atg7
- Autophagy-related protein 3
- Autophagy-related protein 16
- Ubiquitin-like-conjugating enzyme ATG10
- Beclin-1-like protein
- Autophagy-related protein 18b
- Phosphatidylinositol 3-kinase VPS34
- Autophagy-related protein 8i
- Autophagy-related protein 8a
Sequence:
MATESPNSVQKIVVHLRATGGAPILKQSKFKVSGSDKFANVIDFLRRQLHSDSLFVYVNSAFSPNPDESVIDLYNNFGFDGKLVVNYACSMAWG
Protein: Protein white (EC 7.6.2.-) (EC 7.6.2.6) (ATP-binding cassette transporter sub-family G member white) (Broad substrate specificity ATP-binding cassette transporter white) (P10090)
Organism: Drosophila melanogaster (Fruit fly)
Function: ATP-dependent transporter of the ATP-binding cassette (ABC) family which transports various molecules including bioamines, neurotransmitters, metabolic intermediates and second messengers. In the eye, required for the transport of the eye red and brown pigment precursors, guanine and tryptophan, into pigment cell granules. Probably in association with bw/brown, involved in the transport of guanine. Probably in association with st/scarlet involved in the transport of kynurenine and probably tryptophan. Involved in the transport of kynurenine in pupal eyes. May play a role in histamine uptake by the lamina epithelial glia which surrounds photoreceptors R1-R6. In Malpighian tubules, involved in the transport of cGMP, guanine, xanthine, riboflavin, kynurenine and tryptophan. Probably in association with br/brown, involved in aging-induced intestinal stem cell proliferation in the midgut by regulating tetrahydrofolate transport. Probably in association with st/scarlet, plays a role in zinc storage granule biogenesis in Malpighian tubule principal epithelial cells.
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000269|PubMed:11294610, ECO:0000269|PubMed:33820991}; Multi-pass membrane protein {ECO:0000255}. Note=Co-localizes with st/scarlet to pigment granules within pigment cells and retinula cells of the compound eye. {ECO:0000269|PubMed:11294610}.
Interaction partners:
- Polycomb group protein Pc
- Uncharacterized protein, isoform B
- Regulatory protein zeste
- Polycomb protein PHO
- Polyhomeotic-proximal chromatin protein
- Polycomb group protein Psc
- Zinc finger protein su
- Histone-lysine N-methyltransferase trithorax
- Protein yellow
Sequence:
MGQEDQELLIRGGSKHPSAEHLNNGDSGAASQSCINQGFGQAKNYGTLLPPSPPEDSGSGSGQLAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAVVPGREIESRDRIAKICDNFAISKVARDMEQLLATKNLEKPLEQPENGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLLINQWADVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAILIVSFRVLAYLALRLRARRKE
Protein: GTPase activating protein and VPS9 domains 1 (B0QZ65)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVKLDIHTLAHHLKQERLYVNSEKQLIQRLNADVLKTAEKLYRTAWIAKQQRINLDRLIITSAEASPAECCQHAKILEDTQFVDGYKQLGFQETAYGEFLSRLRENPRLIASSLVAGEKLNQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLAMTGSEEGDPRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYITYSQLITLVNFMKSVMSGDQLREDRMALDNLLANLPPAKPGKSSSLEMTPYNTPQLSPATTPANKKNRLPIGKENFSYWSFLLNLIFH
Protein: Mitochondrial succinate-fumarate transporter 1 (AtMSFC1) (Q9M038)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May transport cytoplasmic succinate, derived from fatty acid oxidation, into the mitochondrial matrix in exchange of fumarate during lipid mobilization in seed germination. Conversion of seed-reserved triacylglycerols into sucrose is necessary for growth before the onset of photosynthesis and involves fatty acid beta-oxidation, the glyoxylate cycle and gluconeogenesis.
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- UPF0235 protein At5g63440
- Probable cysteine protease RD21C
- Probable cysteine protease RD21B
- Cysteine proteinase RD21A
- At1g09850
- ACT domain-containing protein ACR1
- DNA polymerase epsilon subunit B
- Developmentally-regulated G-protein 3
- At1g49170
- ADP,ATP carrier protein 1, mitochondrial
Sequence:
MATRTESKKQIPPYMKAVSGSLGGVVEACCLQPIDVIKTRLQLDRVGAYKGIAHCGSKVVRTEGVRALWKGLTPFATHLTLKYTLRMGSNAMFQTAFKDSETGKVSNRGRFLSGFGAGVLEALAIVTPFEVVKIRLQQQKGLSPELFKYKGPIHCARTIVREESILGLWSGAAPTVMRNGTNQAVMFTAKNAFDILLWNKHEGDGKILQPWQSMISGFLAGTAGPFCTGPFDVVKTRLMAQSRDSEGGIRYKGMVHAIRTIYAEEGLVALWRGLLPRLMRIPPGQAIMWAVADQVTGLYEMRYLRNAPL
Protein: Ionotropic receptor 11a (Q9VYN4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Ionotropic receptor 100a
Sequence:
MRFAILWLFSGCLLPGIQVGIWVVVRAQPTGRDVLLSRLGNQQNELNTRRLANASSYLTRNYIANRINTLVVREICVECPYELSERQRQLVDQILASLAPELSVLLHKGTAEETTWEYTLFVVNDHTAFTGQVFIFPDELLEREFFCIVVVSEIQSRQFVRQTVGSIVKSNLQMHFVNVVVVAQLEDGTVGTYSYKLFKANCTPGITVRQINHFDRITGKPQQSMPDLYPVRNGHLGDCPFNVGAAHMPPHLIYKRHKDPPPASNVSIPAEDLAGIDWDLLQLLAKALKFRIQLYMPQEPSQIFGEGNVSGCFRQLADGTVSIAIGGLSGSDKRRSLFSKSTVYHQSNFVMVVRRDRYLGRLGPLILPFRGKLWGVIIVILLLAVLSTCWLRSRLGLSHPIEDLLTVIVGNPIPDHRLPGKGFLRYLLASWMLLTLVLRCAYQARLFDVLRLSRHRPLPKDLSGLIKDNYTMVANGYHDFYPLELTCRQPLDFSARFERVQRAAPDERLTTIALISNLAYWNHKHPNISRLTFVRQPIYMYHLVIYFPRRFFLRPAIDRKIKQLLSAGVMAHIERRYMQYENKRKVASNDPVLLRRITKSIMNGAYRIHGLVIVLATGMFILELLAGRSNGRLRRWMEWVHQ
Protein: Sexual development regulator velC (Q5BBM1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Velvet-domain-containing protein that acts as a positive regulator of sexual development. Positively regulates the production of the sexual fruiting bodies called cleistothecia.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein-methionine methyltransferase laeA
- Velvet complex subunit B
- Spore development regulator vosA
- Developmental regulatory protein wetA
Sequence:
MTTHVGPQTTLLHQTGQISALIAGEAVQTCEASSCQMSGTPFQQWTYVTEGRYTNARTHPSDEDRRRQTTVSNPRYLAQEPPRFLLPTAQNNAPTMSQSATYSTLPVQGFPEQNRVLDNRSDPKYGPLPATTGSLAQYSIQRPSTSRNMENAGSSSSYYDAPSCSRGSVGSIGRMNDLDSQYSGSTTAFPSPVHSDSSPIYPAIAPISGYQQQLPIHQRHTTSSMPSGFENLLHHHSTSPSPPPRCASSSSRYRLFIRQQPLAARACGAGDRDRRPVDPPPIIQLLLTEFNPNSEKDRSILQDPRFTVGCLLYPVRNPSYLPGSGSGAGSSDTNTNSNDKSRHESMSSYSQLGINLEDSHATGQSTPLLSGKAFVSPFFVDEEPDPNTAPAHPSSTDDSTYDASPRTVTHRFRNRPLPKPPACFFIFSDLSVRTAGLYRLQFRLMNWGSIEDTGQSMPILAEVWSEPFRVCAAKDFPGMRDSSLLTLRLKELGFVELKTRGQGMGKGRRVGIGSSKVSSRARVE
Protein: Oxidation resistance protein 1 (Q8N573)
Organism: Homo sapiens (Human)
Function: May be involved in protection from oxidative damage.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:15060142}.
Interaction partners:
- Hypocretin neuropeptide precursor
- Orexin/Hypocretin receptor type 1
Sequence:
MTKDKNSPGLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKHPSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE
Protein: RNA polymerase-associated protein RapA (EC 3.6.4.-) (ATP-dependent helicase HepA) (P60240)
Organism: Escherichia coli (strain K12)
Function: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity).
Interaction partners:
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit omega
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta'
- Dual-specificity RNA pseudouridine synthase RluA
- Putative DNA repair helicase RadD
- DNA polymerase I
- Beta sliding clamp
- DNA polymerase II
- Uridine kinase
Sequence:
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
Protein: (S)-ureidoglycine aminohydrolase (UGHY) (UGlyAH) (EC 3.5.3.26) (P75713)
Organism: Escherichia coli (strain K12)
Function: Involved in the anaerobic nitrogen utilization via the assimilation of allantoin. Catalyzes the second stereospecific hydrolysis reaction (deamination) of the allantoin degradation pathway, producing S-ureidoglycolate and ammonia from S-ureidoglycine.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19935661, ECO:0000269|PubMed:20038185}.
Interaction partners:
- Allantoate amidohydrolase
- Ureidoglycolate dehydrogenase
- Ureidoglycolate lyase
- Allantoinase
- Oxamate carbamoyltransferase subunit AllG
- Oxamate carbamoyltransferase subunit AllF
- Putative allantoin permease
- Oxamate carbamoyltransferase subunit AllH
Sequence:
MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
Protein: Oxidoreductase (O07233)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
- Hydrogenobyrinate a,c-diamide synthase
Sequence:
MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPSVGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALGAREEEFLALKVEGILDCAELLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLAARSEGLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWSYPSALATDHHHGE
Protein: Uncharacterized protein (Q38AR3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPSFTFTIHRRRFLFSLEAEWHPALAKTSNRKESRVLIANCVSAGVCASQNIEKLWKARCRFDMKTVYIVAMCAGGGGLLCILLVITICVLRKRTKTSNTDDDDSAAQSGCALHYIDMSGNERVLDVNALGARDGITLLATIANHCGVQDSSAIALTYVNDARRCVEVDPDLLLRSDGELSDRLMQSKFFPLRLGWRVKPPQPEQKRHQKQRVDEDAKACSAEESRIATRIHECPQEMANGSYKDVVGSTPLPLILPTNSHITSSNPITITAAQYTVEGSNYVLDVNTVVAMQEALRQHTPRSILLEDGSVILVDPARRTVCLRTPQGNQCAVTEHPAGELKYTIDNKGAGQWYPYRCPIYLPPGRWCVRAEASSADHRRVRTTSRVFTVDVVEK
Protein: Secretory 31, isoform B (A1Z7J6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
Sequence:
MKIKELQKTVNIAWSPAQQQQILLAAGTAAQQFDSNANSTLELYSPNFSDATYDLELRASVSSQYKFQKLIWSPVGPHPSGLIVGGCEAGQINIYSADKLLAGKEEPLLKRQDKHTGAVSGLDFNPFQNNLLASCASESEILIWDLNNPETSMSPGTKTQPLEDVKNVAWNRQVQHILASVFSTRCVIWDLRKSQQIIKLSDSQSRVRWHAIEWHPEAATQVWLASEDDQAPVVQLWDLRYATAPAKTYQIHERGVLGMSWCLQDNDLMVSCGKDNRIYCWNPNTKIPEGEILSEVATTASWYSDVQFCPRNPALIASASLEGAVSIYSLHGGTHHLVQTANKIADSFPGMDQFAQEPIPQQATQVVYHDLAHAPKWMKRPCGVAFGFGGKLVSFNGTSKTVKVQQLTTESALVDRANALERSLVDANYSDYCRQRADETPDQHGRYIWYFIKANFELNPKEEMLNLLGYNKDDIDSKFNKFIKETDGNSHSDVDTLTTRISTLTHQTQDNKFDGNAIDSQNHNDFATPPRPQFKVPSGDHSDSLIAEAILTGNVDAAVELCLEAQRIPEALIIASTAGIETLNRTQTRYLLQQKNELSHVISALVSRDWLDFVNRCTVDSWKEALVAALKHSERKVVDICERLGDRLLSECASSAEFTRNAMLCYICAGSIDKLVTAWYQLKRLEQQNPGYKPNTTELQDLAEMVMLMCKSLEQQGISVDLAGRFAGFLTEYGGLLASQGALTAALQYITTLGGGAAASESDVLQSLRDRINNAVNLDYTQPQAAVAAAPHGYQPTRGRGSFSQPQPSAPMPYGQPPNQYAQPSWPAQVPPLQTSYPGAQQPQAPPQIFNPQPVKPEPLAQPPRPLSNASSSGGPPPAGGASSSGGSGLSGRSKYVLDPSVAAPTSSYGMPYNPVPAPVPSAVPFGGGGVPGPAPQPASVPTYNSNAFNTNPIAAAQPYNPSPLMPAQQNQFVPGVNPIETMPPPAVPPVIQNVQRNPTPPPGWNDPPALKSSRAPKPKPVVEPSAAIFHPLFPVDPNQNQNGYVDPSQYQHAAPLGGVPNTYYNPAAFNNNPQQQQQHQQSYLQPQQPAPGIQQPNWQGQQQTIGYTEQPAPIQQQRQPAPPKEKPPLPEEYIYLQTVLEELKNRCLGATNDPRTKRKFVDVVKRLENLYDCLRDGKLTPTTVQYLNQIVQYIQISDYANAMEIHTQIAFGTDFAQCAGFMQGLKVLLQSASELQLVLR
Protein: C3H1-type domain-containing protein (O01299)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTGYGYNSNLVQQVQQPQVLQGVNEEWTHTTGQSQYYHTDSGATGLSNPMLYGSGWYQPPNYNNYPAAPEHNVVDQQRSPPDAMDNTRALAYQNQMFMMQAANLAPPPQPRVSFSDEELYQALNMSPLPPTATFHALHQQQQQQQQHQSMKQQHAMHLQQQPQTDYLSSEVCYPSTSSYEPSGYNESGYCPQNSTILPDDPQNYQHGNDGDDEESFGEPERYEPMSPTFSIHSFAPTTSTNTAEAEDLEVELINNHKPTPRYQLSDDIDIFLHTGTTDDTEYNDDSDSRPTTTFSHRSTKAPTPPASRPAYAQKFTAAAQNLKPEQQQPTTSDITSPISKTSPLFLQTTGQDPAGFTPLLTPNSDALLQKKLSEVVHNPPQRAIGLSAFPAFPQQPPHLTRFQENQRYEGNFVEYQPPPPQQHQQQQPQAPEGFYPPISLNTRYDYDSDRDILPLLLDTFQPLPAPPQIPPVTVSVPVSVPELLTSTKKPSQPAKVPAAPIKAPRLSDQELESESQKLALDVISNLFSNKKEIIDRAAVLSAPKKPVARNLFCNDPESLEKAKSSEPLTMSVLDDWETADDDDLTVRMENLLKDKKKEEKKAQSMSKAPPPPQRNSDWDTAFLQHVLEIYGVPDYKMQEDVVKAMETIGNGDCKVMWMERKVVFAVFESVNRAKNCLTLSKHDWLRFRSLADSPKVVQDSAKTNAASLGILKKKQQTTATVARRMVENALGKKATVSTEKRQEERKQLAAAKAAKKNTIQWD
Protein: Carbonic anhydrase 5A, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VA) (Carbonic anhydrase VA) (CA-VA) (P35218)
Organism: Homo sapiens (Human)
Function: Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3. Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:8356065}.
Interaction partners:
- 1,25-dihydroxyvitamin D
- Carbonic anhydrase 5B, mitochondrial
Sequence:
MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS