wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1) (P43588)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. RPN11 is the only catalytically active member of the lid and serves as the essential deubiquitinase of the proteasome.
Interaction partners:
- Proteasome subunit alpha type-1
- Probable proteasome subunit alpha type-7
- 26S proteasome regulatory subunit 6A
- 26S proteasome regulatory subunit RPN2
- 26S proteasome regulatory subunit 7 homolog
- 26S proteasome regulatory subunit 8 homolog
- 26S proteasome regulatory subunit RPN9
- 26S proteasome regulatory subunit RPN13
- 26S proteasome regulatory subunit 4 homolog
- Polyubiquitin
Sequence:
MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGVNSVAIK
Protein: Transcription factor Ouib (Protein ouija board) (Q9VHM6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor required for ecdysteroid production in the prothoracic gland by activating transcription of the ecdysteroid biosynthesis gene spok. Binds to the 5'-AGCTTTATTATTTAG-3' DNA sequence in the spok enhancer region.
Subcellular location: Nucleus {ECO:0000305|PubMed:26658797}.
Interaction partners:
- Spookier
- Cholesterol 7-desaturase nvd
Sequence:
MLNIVCRVCGRQKICEKSLNLFDLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALAFRKLCIKTQTKWLTIEDDSSSGDEDTNDNSELESEKCAFSDFGKKKEGELVEETFQVLIEEEPMDKTLNRDAKAQLREDGIDEKCVPSQKIIKVSTKLDDQIYICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAGELRAHHRVHTGEQPFACRFCEKRYVSYMGRLIHERTHTNDRPYVCEECGKKFTTAYVLKNHMVIHTGERNFRCDICDRSFQRKAHLVTHTRSMMHLQNVKKQKS
Protein: Troponin C, isoform 2 (Q09665)
Organism: Caenorhabditis elegans
Interaction partners:
- Troponin I 4
- Troponin T
- Troponin T
- Troponin T, skeletal muscle
- Troponin I 1
- TropoNin T
- Troponin I 3
- Troponin I 2
- Tropomyosin isoforms a/b/d/f
Sequence:
MGDVVADALEKLSADQIEQFRKYFNMFDKEGKGYIRATQVGQILRTMGQAFEERDLKQLIKEFDADGSGEIEFEEFAAMVANFVVNNENDEGLEEELREAFRLYDKEGNGYINVSDLRDILRALDDNVSEEELDEMIAEIDADGSGTVDFDEFMEMMSGE
Protein: T-cell differentiation antigen CD6 (T12) (TP120) (CD antigen CD6) [Cleaved into: Soluble CD6] (P30203)
Organism: Homo sapiens (Human)
Function: Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria. LPS binding leads to the activation of signaling cascades and down-stream MAP kinases. Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15048703, ECO:0000269|PubMed:15294938, ECO:0000269|PubMed:16352806, ECO:0000269|PubMed:16914752, ECO:0000269|PubMed:17371992, ECO:0000269|PubMed:17601777, ECO:0000269|PubMed:24945728, ECO:0000269|PubMed:9013954}; Single-pass type I membrane protein {ECO:0000269|PubMed:17371992}. Note=Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells (PubMed:15294938, PubMed:16352806). Colocalizes with the TCR/CD3 complex at the immunological synapse (PubMed:15294938). {ECO:0000269|PubMed:15294938}.; SUBCELLULAR LOCATION: [Soluble CD6]: Secreted {ECO:0000269|PubMed:17601777}. Note=The origins of the secreted form are not clear, but it might be created by proteolytic shedding of the ectodomain. {ECO:0000305}.
Interaction partners:
- CD166 antigen
- T-cell surface glycoprotein CD5
- T-cell surface antigen CD2
- Lymphocyte cytosolic protein 2
- T-cell antigen CD7
- Syntenin-1
- T-cell surface glycoprotein CD3 zeta chain
- Tyrosine-protein kinase ITK/TSK
- T-cell surface glycoprotein CD3 delta chain
- T-cell surface glycoprotein CD3 epsilon chain
Sequence:
MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRELMLLIPSIVLGILLLGSLIFIAFILLRIKGKYALPVMVNHQHLPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPPPEDSDSGSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPWNPQVFSSERSSFLEQPPNLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDNDDYDDISAA
Protein: Hypoxia-inducible factor 1-alpha (A8MYV6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
Interaction partners:
Sequence:
MEGAGGANDKKNRISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQTPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTVTVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYRDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKRKMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
Protein: RIKEN cDNA 2310061I04 gene (B8JJ66)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MVLPPRKREKGPGPELHSGCLDGLRSLFEGPPCPYPGAVIPFQAPGPSHSSPTTPSGDESMEEHLAVMHERLRQELPTLFLRSHDYTIYSMDVEFINEILNIRTKGRTFYVMSLTLCRFLVWNYFAQFRLEILQLTRHPENWTLQARWRLIGLPIHMLFLRFYRRDKEDLYRTFDAFSTFYLNSSGLICRHHLDKLMPSHSPSTPVKKLLVGALVALGLSEPEPSLHLCSKA
Protein: Mediator of RNA polymerase II transcription subunit 21 (A0A0S2Z545)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU366036}.
Interaction partners:
Sequence:
MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFNNIQTAINKDQPANPTEVSFSRVCPAFCSTDCTNSKRH
Protein: Probable sugar-transport ATP-binding protein ABC transporter (O53482)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable sugar-transport integral membrane protein ABC transporter
- Probable sugar-transport integral membrane protein ABC transporter
- Probable sugar-binding lipoprotein
- Trehalose transport system permease protein SugA
- Trehalose transport system permease protein SugB
- Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpA
- Probable sugar-transport integral membrane protein ABC transporter UspB
- Probable sugar-transport integral membrane protein ABC transporter UspA
- Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpE
- Probable Sn-glycerol-3-phosphate-binding lipoprotein UgpB
Sequence:
MASVSFEQATRRYPGTDRPALDRLDLIVGDGEFVVLVGPSGCGKTTSLRMVAGLETLDCGRIRIGERDVTEVDPKDRDVAMVFQNYALYPHMTVAQNMGFALKVAKIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQRQRVAMGRAIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHDQVEAMTMGDRVAVLSDGVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFRLSIADSTVSLGDWQILLPRAVVGTAAEVIIGVRPEHLELGGAGIEMDVDMVEELGADAYLYGRIVSGGCEMDQSIVARVDGRGPPERGSRVRLCPTPGHLHFFAVDGRRIPG
Protein: 12-oxophytodienoate reductase 1 (EC 1.3.1.42) (12-oxophytodienoate-10,11-reductase 1) (AtOPR1) (OPDA-reductase 1) (FS-AT-I) (Q8LAH7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Specifically cleaves olefinic bonds in alpha,beta-unsaturated carbonyls and may be involved in detoxification or modification of these reactive compounds. May be involved in the biosynthesis or metabolism of oxylipin signaling molecules (Probable). In vitro, reduces 9R,13R-12-oxophytodienoic acid (9R,13R-OPDA) to 9R,13R-OPC-8:0, but only poorly 9S,13S-OPDA, the natural precursor of jasmonic acid. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro and in vivo by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12445129}.
Interaction partners:
- Allene oxide cyclase 2, chloroplastic
- Allene oxide cyclase 3, chloroplastic
- Allene oxide cyclase 1, chloroplastic
- Allene oxide cyclase 4, chloroplastic
- Allene oxide synthase, chloroplastic
- Peroxisomal OPC-8:0-CoA ligase 1
- Lipoxygenase 4, chloroplastic
- Lipoxygenase 3, chloroplastic
- Lipoxygenase 2, chloroplastic
- Lipoxygenase 6, chloroplastic
Sequence:
MENGEAKQSVPLLTPYKMGRFNLSHRVVLAPLTRQRSYGNVPQPHAAIYYSQRTTPGGFLITEATGVSDTAQGYQDTPGIWTKEHVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNSGFQPNGKAPISCSDKPLMPQIRSNGIDEALFTPPRRLGIEEIPGIVNDFRLAARNAMEAGFDGVEIHGANGYLIDQFMKDTVNDRTDEYGGSLQNRCKFPLEIVDAVAKEIGPDRVGIRLSPFADYMESGDTNPGALGLYMAESLNKYGILYCHVIEARMKTMGEVHACPHTLMPMRKAFKGTFISAGGFTREDGNEAVSKGRTDLVAYGRWFLANPDLPKRFQVDAPLNKYDRPTFYTSDPVVGYTDYPFLESTA
Protein: Tax1-binding protein 3 (Q8AWD4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR037712}. Nucleus {ECO:0000256|PIRNR:PIRNR037712}. Cell membrane {ECO:0000256|PIRNR:PIRNR037712}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR037712}; Cytoplasmic side {ECO:0000256|PIRNR:PIRNR037712}. Note=Recruited to the cell membrane by interaction with membrane proteins. {ECO:0000256|PIRNR:PIRNR037712}.
Interaction partners:
Sequence:
MSFIPGQPVTAVVQRIEILKLRDGDNLILGFSIGGGIDQDPSQNPFSEDKADKGIYVTRVSEGGPAEVAGLRVGDKIMQVNGWDMTMVTHDQARKRLTKKKEDVVRLLISRKSLEEVVRQSMMQR
Protein: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 7.1.1.2) (Q59TD5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU364066}; Peripheral membrane protein {ECO:0000256|RuleBase:RU364066}; Matrix side {ECO:0000256|RuleBase:RU364066}.
Interaction partners:
- Fesur1p
- NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial
- NAD-dependent epimerase/dehydratase domain-containing protein
- NADH-ubiquinone oxidoreductase chain 5
- NADH dehydrogenase 1 alpha subcomplex subunit
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- Cytochrome b-c1 complex catalytic subunit, mitochondrial
- NADH-ubiquinone oxidoreductase
- Uncharacterized protein
Sequence:
MLSNFKIKPRTLLRGLATAAADPAANPNRVHGGLKDQDRIFQNVYGTYGHDLKSAQKMGDWYKTKEIILKGDKWIIDEMKKSGLRGRGGAGFPSGLKWSFMNPPGWEKNVGPRYLVVNADEGEPGTCKDREIIRKDPHKLVEGCLLAGRAMNATAAYIYIRGEFYNETVVLQNAINEAYKAGLIGKNACGSGYDFDIYIHRGMGAYICGEETALIESIEGKAGKPRLKPPFPAGVGLFGRPTTVANVESVSVAPTILRRGGDWFASFGRERNAGTKLFCISGHVNEPCTVEEEMSIPLKELLEKHCGGIVGGWDNLLGVIPGGSSVPIMPKETCDNVLMDYDALRDVGSGLGTAAVIVMNKQTDIIRAIQRFSHFYKHESCGQCTPCREGTTWLQRMMDRFYTGQATEKEIDQIFELTKEIEGHTICALGDAAAWPVQGLIKSFRPVMVDRIKEFQQKHAGEHLEYGGWVDGGKVKNGVVIDNPLPSGHH
Protein: Serine protease 42 (EC 3.4.21.-) (Testis serine protease 2) (Q8VIF2)
Organism: Mus musculus (Mouse)
Function: Plays a role in spermatogenesis. Involved in germ cell survival during meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23536369}. Cell membrane {ECO:0000269|PubMed:23536369}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:23536369}.
Interaction partners:
Sequence:
MASGGGSLGLIVFLLLLQPKPCEAWAAASVLSTSGFPSGFSEAPRDNPPPPTRVRMSKATTRSPFMNFSLVCGQPFMKIMGGVDAEEGKWPWQVSVRVRHMHVCGGSLINSQWVLTAAHCIYSRIQYNVKVGDRSVYRQNTSLVIPIKTIFVHPKFSTTIVVKNDIALLKLQHPVNFTTNIYPVCIPSESFPVKAGTKCWVTGWGKLVPGAPDVPTEILQEVDQNVILYEECNEMLKKATSSSVDLVKRGMVCGYKERGKDACQGDSGGPMSCEFENKWVQVGVVSWGISCGRKGYPGVYTDVAFYSKWLIAVVNQADCLHPVVFLVLLLCSLTS
Protein: Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1) (Q9D0T2)
Organism: Mus musculus (Mouse)
Function: Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9UNI6}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9UNI6}. Note=Primarily nuclear. Detected in a mesh-like pattern in the cytosol. {ECO:0000250|UniProtKB:Q9UNI6}.
Interaction partners:
- Cerebellar degeneration-related protein 2
Sequence:
MLEAQGSNHGCERQAPTASPASSAGHAVEVRPGLYLGGAAAVAEPGHLREAGITAVLTVDSEPAFPAGAGFEGLRSLFVPALDKPETDLLSHLDRCVAFIGQARSEGRAVLVHCHAGVSRSVAVVMAFIMKTDQLTFEKAYDILRTVKPEAKVNEGFEWQLKLYEAMGYEVDTSSAFYKQYRLQKVTEKCPKLWNLPQELFAVDPTTISQGLKDDILYKCRKCRRSLFRHSSILGHSEGSGPIAFAHKRTAPSSVLTTGSQAQCTSYFIEPVQWMESTLLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMKMLPVLGSQTKKL
Protein: D-threitol-binding protein (A0QYB5)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: Part of an ABC transporter complex involved in D-threitol import. Binds D-threitol. Functions in the transport for the degradation pathway of D-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source.
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
- Ribose transport ATP-binding protein RbsA
- Ribose transport system permease protein RbsC
- Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
- Ribose transport system permease protein RbsC
- Ribose transport ATP-binding protein RbsA
- Ribose transport ATP-binding protein RbsA
- Xylitol-binding protein
- Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
- Ribose transport system permease protein RbsC
- Ribose transport system permease protein RbsC
Sequence:
MRLGTTAFAIASATALGLGLTACGAGDPAANSDTTRIGVTVYDMSSFITAGKEGMDAYAKDNNIELIWNSANLDVSTQASQVDSMINQGVDAIIVVPVQADSLAPQVASAKAKGIPLVPVNAALDSKDIAGNVQPDDVAAGAQEMQMMADRLGGKGNIVILQGPLGQSGELDRSKGIEQVLAKYPDIKVLAKDTANWKRDEAVNKMKNWISGFGPQIDGVVAQNDDMGLGALQALKESGRTGVPIVGIDGIEDGLNAVKSGDFIGTSLQNGTVELAAGLAVANRLAKGEPVNKEPVYIMPAITKDNVDVAIEHVVTERQQFLDGLTELINKNLETGDIAYEGIPGQKQP
Protein: C-C chemokine receptor-like 2 (Chemokine receptor CCR11) (Chemokine receptor X) (Putative MCP-1 chemokine receptor) (O00421)
Organism: Homo sapiens (Human)
Function: Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18397265, ECO:0000269|PubMed:20002784}; Multi-pass membrane protein {ECO:0000269|PubMed:18397265, ECO:0000269|PubMed:20002784}.
Interaction partners:
- C-C motif chemokine 20
- C-C motif chemokine 19
- Retinoic acid receptor responder protein 2
- Defensin beta 4A
- C-C motif chemokine 2
- Beta-defensin 1
- C-X-C motif chemokine 16
- C-C chemokine receptor type 2
- Beta-defensin 103
- C-C motif chemokine 5
Sequence:
MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
Protein: Small GTPase, putative (Q38DS4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Rab GDP dissociation inhibitor
- Vacuolar protein sorting complex subunit, putative
- Pep3/Vps18/deep orange beta-propeller domain-containing protein
- Vacuolar protein sorting 33, putative
- Vacuolar assembly protein vps41, putative
- RING-type domain-containing protein
- GTPase activating protein, putative
- Uncharacterized protein
- Tubulin alpha chain
- Tubulin beta chain
Sequence:
MAPNRQLLKIIILGDSGVGKTALVHQYVNKNFDNRYKATIGADFLTRDVEIDGKLVTLQIWDTAGQERFQSLGSAFYRGADACVLVFDLTDSESFSHINSWLEEFRAQAGQRECVLIGNKSDLTERRQVTSRTAEAWCESLKNGEGGDASLGAAAGEETMGSIQYFEASAKANVGVEEAFLTVSKAALAKKATAEEGVALPQSIRLGQQRPSTKKSDCAC
Protein: Myo-inositol transporter 3A (J9VLY3)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Transporter for myo-inositol.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P30605}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSATHIENRDDSFLENKGIDHIGRPENNNGSQEPPSPSGFGGHLIDENLVRVEGEDKVTWYLCFLISASAIAGFLFGYDTGVVGVALPLVGTDLGGSALNSSQQEIITAGTTIGAIFGSAILGGWGDRLGRKGAILVSDVFFTIGAVIIASSYSVPQIIVGRIILGIGVGGAAVIAPLFITETAPTAVRGRCIGVNAFFIPFGQVVSDAIGAGVQNMHNGWRLLFALGAVPSLLQLLLFHYLPESPRILILKGDTEGARTVFQRIYPTATSEMIEYKFRVAHEYIAATTALQSGTTFWERVKKVLKTGSYRRSIIAVSALQAAGQLTGFNTLLYYAGTLFGLLGLSNPALGGLIPAGTNAVFVLIGMSLVDKVGRRGLLLIGVPIMLLGHVWNIVSFYYMCKPTGGFLDTSYSYDTTDVGIVIGGIVFFVVGYGLTYSHLVWYQAEYLTLEVRSMGSGIATTVCWIANLVVSVSYLSELETMTPSGTYGFYFGISVIGFVFLVFCLPETKQLSIDETSLLFEDDWGVKRSAQMRKERRETRKRLQDAELGEAATAHLEARQQKSTSVSPAELSKFMAGLKGGKRTPSASV
Protein: Mitotic spindle assembly checkpoint protein MAD2B (Mad2l2-A protein) (Mitotic arrest defective protein 2B) (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (xMAD2L2) (Q8QFR4)
Organism: Xenopus laevis (African clawed frog)
Function: Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Through transcriptional regulation may play a role in epithelial-mesenchymal transdifferentiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:11459825}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MTTLTRQDLNFGQVVADILCEFLEVAVHLILYVREVYPTGIFQKRKKYNVPVQMSCHPELNRYIQDTLHCVKPLIEKNDVEKVVVVILDKEHHPVERFVFEIAQPPLLSISSDSLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTLLVHTREAATRNMEKIQVIKDFPWILADEQDVHMQEPRLIPLKTMTSDILKMQLYVEERAQKST
Protein: Gap junction beta-3 protein (Connexin-31) (Cx31) (O75712)
Organism: Homo sapiens (Human)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Interaction partners:
- Potassium voltage-gated channel subfamily KQT member 4
- Gap junction beta-2 protein
- Pendrin
- Gap junction beta-6 protein
- Gap junction beta-4 protein
Sequence:
MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPI
Protein: Probable conserved lipoprotein LpqD (O50416)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Conserved protein
- Putative lipoprotein LprB
Sequence:
MAKRTPVRKACTVLAVLAATLLLGACGGPTQPRSITLTFIRNAQSQANADGIIDTDMPGSGLSADGKAEAQQVAHQVSRRDVDSIYSSPMAADQQTAGPLAGELGKQVEILPGLQAINAGWFNGKPESMANSTYMLAPADWLAGDVHNTIPGSISGTEFNSQFSAAVRKIYDSGHNTPVVFSQGVAIMIWTLMNARNSRDSLLTTHPLPNIGRVVITGNPVTGWRLVEWDGIRNFT
Protein: H-2 class I histocompatibility antigen, Q8 alpha chain (P14430)
Organism: Mus musculus (Mouse)
Function: Involved in the presentation of foreign antigens to the immune system.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- H-2 class I histocompatibility antigen, Q7 alpha chain
- Tapasin
- H-2 class II histocompatibility antigen, E-B beta chain
- H-2 class II histocompatibility antigen, A-B alpha chain
- Beta-2-microglobulin
- Class II histocompatibility antigen, M alpha chain
- Antigen peptide transporter 1
- H-2 class II histocompatibility antigen gamma chain
- Class II histocompatibility antigen, M beta 1 chain
- H-2 class II histocompatibility antigen, A beta chain
Sequence:
MALTMLLLLVAAALTLIETRAGPHSLRYFHTAVSWPGLVEPRFIIVGYVDDTQFVRFDSDAENPRMEPRARWMEQEGPEYWERETQKAKGHEESFRVSLRTAQRYYNQSKGGSHTLQWMYGCDVGSDERLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITLHKWEQAGIAERDRAYLEGACVQSLRRYLQLRKETLLCTDPPKAHVTHHPRSYGAVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVNHEGLPEPLTLRWEPPPSTVSNMANVAILVVLVAWPSLELWWIL
Protein: Homeobox protein six1b (Homeobox protein six1a) (Sine oculis homeobox homolog 1a) (Sine oculis homeobox homolog 1b) (Q6NZ04)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Depending on context, functions as transcriptional repressor or activator. Transcriptional activation is enhanced by eya1 (in vitro). Plays an important role in the development of the inner ear, where it promotes hair cell proliferation and inhibits proliferation of neural progenitor cells. Required for normal myogenesis. Plays a role in the development of fast muscle fibers throughout the body, as well as the development of craniofacial muscles. Required for normal expression of myod1 and myog during myogenesis.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q15475}. Cytoplasm {ECO:0000250|UniProtKB:Q15475}.
Interaction partners:
- Eyes absent homolog
- Eyes absent homolog
- Paired box 3a
- Eyes absent homolog
- Myoblast determination protein 1 homolog
- Myogenin.
- Paired box 7a
- Homeobox protein Dlx2b
- Paired box protein Pax-2a
- Atonal bHLH transcription factor 1a
Sequence:
MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENSENNNTGANKQNQLSPLDGGKSLMSSSEDEFSPPQSPDQNSVLLLQGNMSHPGASAYSMTGLGAAQSVHGMQGHPHQLQDSLLGPLTSSLVDLGS
Protein: SSD domain-containing protein (O44978)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Ground-like domain-containing protein
- Ground-like domain-containing protein
Sequence:
MGWDVISAVVARLLAAYPVYSILLSILSILVLSSGLVHIRLEPDIRKAFSPDDSDAGYETRVWLEYYGLDIYPERAFCIFTAKRENSSILQEGALADIYTVDNRLSAAVGYQDGDGRKNCDPLCDLNSPFHLLANLTRRNNGTTSVFTYPDMPYSGLDIFLGLHLSNADFEPPTERISSKSLVLWYFSRSDTPEGKLAFKDAIDELFQLSKNSSAFEHVQFTIFSDQVANREMIRGAIEATTLMTIGFFLLLTQVIIVIVRLSSVKMAFYLVATSLLTPMAATVASFGAICWMGFPSFSIQCVTPFLVLGIGVDDAFILLHRWKHHIAITDTPRRLEQVIVDVGPSITITSLTNIIAFGIGFLTPTPQMSLFCLTASLALLLDYIFTYTILAPIVFLCNDPDYKSIANETEPKISRADTWLSKYSSFVCSVKGRVACIMVLLGMYALTTYGVVTMKTTFEPAKAFPSNSKLVDSLSNIKPVFNRYFPITVIVNNPPNIEIKAEYDSFNNMMDRLEHVPGIRGDNRSLIFLPQYVNFDKTMNILSTLVGEKYRPSYDNLPTWMDAIGNPPLVKYHMGDDNKTIVTAFRLTLLGKGMSEWAERARAMQHIRTILHEESQFNATLFDCDSAILSIILTVGTDLIGSIAVTVVCMAIVCFVFIANFNAVAVITSVIASICYVLVGGLSLWGADLDPVIQVDVLLATGFSVDYTAHVAYNFFRARGTPQERVYSSLAEMAMPMCEAGLSTFLCMLPLIFVPTYAIVCFAKTVFLVVAIGLLHGLFILPVILALFSKDSINEKDNIPAAITFSAAEPLVDKDLNAV