wanglab/gogpt-training-data huggingface dataset:
Protein: GH27708p (PAR-domain protein 1, isoform D) (Q8SZT1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein cycle
- Circadian locomoter output cycles protein kaput
- Transcription factor cwo
- Protein timeless
- Discs overgrown protein kinase
- Protein PDF
- Cryptochrome-1
- Adaptor protein complex AP-3 small chain sigma3
- Period circadian protein
- GH23983p
Sequence:
MSSDTNSCTSFFAQEHANATLSQYFQQLNSHVAAAAAGNSGGNSSSSNNNNSSGNNSSSGNSDSGNDGSMTGSSGTMDNHRSSVSSNDSGKSSATGGGGAGATSNNGVNAWALQQQQQTAALHHQQQQQHQQQQQHQQHLQQHHQAHHQHVLQQQQQQQQQHSQHQHQQQHHGHPLHPHHTHQQQQQQQQQQQPPPQHHQQQQQQHAQQQQQQHHAAQLAHTLSSAAVAAAAGNTGGNTNPHSIFGTGNFHYKTNNSWTLPTLTYQRIYQENPHYQRNSFMDPQSNAAAAAAAAAASCNAAAVAAAAAVASGNQGSNGNASGNGNAVVAATGNGNGGNPGQNNNNNNGNNSGNSNNNSNNNVSSVQHVANAVAAAVIANEHHNHLNSLKARFQPASSGRKSPFLGFICKSNGKSTSNSKEIICPDDKYKEEGDIWNVEAQTAFLGPNLWDKTLPYDADLKVTQYADLDEFLSENNIPDGLPGTHLGHSSGLGHRSDSLGHAAGLSLGLGHITTKRERSPSPSDCISPDTLNPPSPAESTFSFASSGRDFDPRTRAFSDEELKPQPMIKKSRKQFVPDELKDDKYWARRRKNNIAAKRSRDARRQKENQIAMRARYLEKENATLHQEVEQLKQENMDLRARLSKFQDV
Protein: DUF19 domain-containing protein (Q20865)
Organism: Caenorhabditis elegans
Interaction partners:
- DUF19 domain-containing protein
- DUF19 domain-containing protein
- MATH domain-containing protein
Sequence:
MLLRFIIGLSSVLLVTGLFNPLLPTLGDYLLTDQQVQKYFSVAGPSNLAIGTCNSVPFASAQAGFASSVGLAPTTTWREANILTNATIGMIDQGMDQLAAVCQARQQFVQTLGAAYDTCTDRFYLISLGNTDWWNVMQYTHLMKHLEFICSTGFDVYQSNIDCIRKGETTDGNQYRACFYKFNATVNANPNNFCGATETFIGCIKDFFDTECNLYVGWMQCELERIGFAYDCYGLSC
Protein: Integrase (Q76353)
Organism: Human immunodeficiency virus type 1 (HIV-1)
Interaction partners:
Sequence:
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
Protein: Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.12) (ATP-dependent helicase CHD2) (E9PZM4)
Organism: Mus musculus (Mouse)
Function: DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression.
Subcellular location: Nucleus {ECO:0000269|PubMed:22569126}. Note=Binds to myogenic gene promoters.
Interaction partners:
Sequence:
MMRNKDKSQEEDSSLHSNASSRSASEEVSGSDSGSQSESEQGSEPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNVKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDEQEQGTSAESEAEQKKGKARRPVPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGGDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSDDFDTEREEGEVQYLIKWKGWSYIHSTWESEDSLQQQKVKGLKKLENFKKKEDEVKQWLGKVSPEDVEYFSCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGESLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKAPEDSERESGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKESTSEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVASGEEAKLKKRKPRVKKENKAPRLKDEHGLEPASPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKERKKSKDKKEKVKGGDGKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLSVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDSLGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYSHPNKRHFSNADRGDWQRERKFNYGGGNSAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPSLHTALSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT
Protein: 60 kDa heat shock protein, mitochondrial (C9JCQ4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIG
Protein: Uncharacterized protein C688.07c (Q9P6L9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Note=Localizes at the cell tip and the barrier septum.
Interaction partners:
- Probable Rho-GTPase-activating protein 7
- mRNA export factor elf1
- Elongation factor 3
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS7
Sequence:
MEENTAQKQSNATGLQRHVSGRWISNVPSYEGNEWSSEESESEDKESNLTSSENIGKNPERELNSDGTDRIIEEEEEEDDIENEASSFSEQSENENYDFSYPGTFVYRKAASSSHETLATKVVSADESARLWAEKRRFLLQKLGKDPNSKPIDYKSSMASSSTRSSQSSQVSAIQPQSQDDNRVSDIRQMENRRELNVKRRSVSSPAEDLAIRPLSFSRYKKAEEIPESLPPIKGRDSFSSVRELNESNVFARAPNKNRFSFASVAETGSGSNFSRATSSRSSKTRSVVYEPNHRHTSFFGDTLSNLSSSLNDKKSPNDDHAVLDSELMEQTLPDSAEAVEIANNVKEDIVSTANDDANELDNTSEKATLETSSKPVTEQAIEQSEVVQEVEEGDTNMTTNTILKPTDEIINKGYAYSITSSHSNHSNEKFEQIPSPDEKLSRTDIDTHVKQLQTTKSTDSLSIPFVESPQQNPEEELSDSLSNDFGIDAEKEKDENLSKPEHHPSITSVNSPFLYSPSKQPSGELDEENLKLRLQDSDVDDEVATIRSLKQNNATNSEVETVTNDPSFSQQPGTHSRILRNFDAISSIDSIPDSFSDSAVDLPVDSSKYTLVGKTQSNSNLLQDNAEKHISKSNLEKVDVKGDTSPNSVEQGIEPQAASVVGSPRSSLVSNNSLEEGALLKNSESLESIYGYLSEEPDPALTKLNTEDPFWTKGSSDDEHTIASVEQDVYPYKTSLPTIVEATTSHTESSNSKAPAIEETTTTKVEVVAAHDAVSISSNSSTHKSHSEPLNRDELEVAALSRGSLPEPPKPNKQIVVQEEDQRDTLSLKTSTTGLSSHSKSAENNSTQQSTTSPSINSGASADAVSSGISKKADNSETNLNYFATLDAFVKSPLMSFDGLGELGSTDQRYNFFNQKIQEYSAYDSGLDNWIQFCLEKDGEAPKEAPPPPRSEPVSTTTKLAKRITQPSLSPARSTVTITHNIATEAKKKSKSAANDILHLFKKKAKSEQSNAKSSSSSIKESKKMKTLFGKKLGFKS
Protein: Nuclear pore complex protein NUP62 (Nucleoporin 62) (NP62) (Protein EMBRYO DEFECTIVE 2766) (Q8L7F7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:21189294}. Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
Interaction partners:
- Nuclear pore complex protein NUP58
- Nuclear pore complex protein NUP54
- Nuclear pore complex protein NUP88
- Nuclear pore complex protein NUP214
- Nuclear pore complex protein NUP35
- Nuclear pore complex protein NUP1
- Nuclear pore complex protein NUP43
- Nuclear pore complex protein NUP160
- Nuclear pore complex protein NUP93A
- Nuclear pore complex protein NUP107
Sequence:
MSGFPFGQSNSVGGFSFGSSSATNSSSASSTTSPLSFSFNQSSNPSSTGFGFGSSVSSTPASSTTPSFGFGASSTPSFGFGSSASSSTPSFGFGSSASVTPASTTPSFGFGTAASSSAPAPSLFGSSTTNASSAAPGSSPFGFVTSSASSTATPSSSLFGAPASSAATPSSSPFGAAPASGSTPLFGSSPSLFSAPSSASASNSSLFGASSSAATSTSPLFGAPSSATGATPSFSVASSAPGSSSSIFGATGSSPSFSVASSASGSSPSIFGATGSSPFFGSSSSAGSTPSLFASSSSGATTSSPSPFGVSTFNSSSTSNTSNASASPFSASTGFSFLKSTASSTTSSTTPSAPPQTASSSSSFSFGTSANSGFNLSTGSSAAPASSTSGAVFSIATTTTTSSSTPAATSAPASSAPASTMAFPSFGVTSSATNTTPASSAATFSTTGFGLASSTPATGSTNSFTGFAVPKTSTPASSSQPQTTSPAFSFSLPSSTSTTAPATSSATTTQTTLVVPSSSGTSTAVAPVAGSPKLPSEITGKTVEEIIKEWNTELQERTGRFRKQANAIAEWDKRILQNRDVLLRLEIEVAKVVETQSSLERQLELIETHQQEVDKALQSMEEEAERIYNDERKSLLDDEAASTRDAMYEQSELVERELEHMTEQIRSIIQSVNANQGGELEAIDGMSPLDVVVRILNNQLSSLMWIDEKAEEFSSRIQKIALQGSGGDRELMAPKHWMS
Protein: Ribonuclease T2 (EC 4.6.1.19) (Ribonuclease 6) (O00584)
Organism: Homo sapiens (Human)
Function: Ribonuclease that plays an essential role in innate immune response by recognizing and degrading RNAs from microbial pathogens that are subsequently sensed by TLR8. Cleaves preferentially single-stranded RNA molecules between purine and uridine residues, which critically contributes to the supply of catabolic uridine and the generation of purine-2',3'-cyclophosphate-terminated oligoribonucleotides. In turn, RNase T2 degradation products promote the RNA-dependent activation of TLR8. Also plays a key role in degradation of mitochondrial RNA and processing of non-coding RNA imported from the cytosol into mitochondria. Participates as well in degradation of mitochondrion-associated cytosolic rRNAs.
Subcellular location: Secreted {ECO:0000269|PubMed:15809705, ECO:0000269|PubMed:16620762}. Lysosome lumen {ECO:0000269|PubMed:16620762}. Endoplasmic reticulum lumen {ECO:0000269|PubMed:16620762}. Mitochondrion intermembrane space {ECO:0000269|PubMed:28730546, ECO:0000269|PubMed:30184494, ECO:0000269|PubMed:30385512}. Note=Full-length RNASET2 is found in the endoplasmic reticulum while smaller RNASET2 proteolytic products are found in the lysosome fraction. {ECO:0000269|PubMed:16620762}.
Interaction partners:
- Centrosomal protein 43
- Ribonuclease K6
- Angiogenin
- Non-secretory ribonuclease
- Ribonuclease pancreatic
Sequence:
MRPAALRGALLGCLCLALLCLGGADKRLRDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDYWTIHGLWPDKSEGCNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSINYYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAESRGLRVCEDGPVFYPPPKKTKH
Protein: sphinganine-1-phosphate aldolase (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase) (Q585W1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Phosphatidic acid phosphatase, putative
- Phosphatidic acid phosphatase alpha, putative
- DAGKc domain-containing protein
Sequence:
MSLSCFLDRSLQGKRPSHIVCLTVGAIFATKVLIYVARDGSIIKRLHAAKWRVVRFFVEPIIKKEVKKSAEGIKMPSKPGEFKAKRLPKEGFSDEEVINLVSEFHQNLDKTFEDGTLSGAVYHGEHSHTKLLNRVVKMFAWSNPLHSDVFGAVRKMEAEVVSMVVHMFNGHLLPDACGTVTSGGTESIVMALKAYRDWGRARRGIERPSVIVGITAHPAFDKGAEYFGINLVKIPVDPITKQVDAKEMEKYIRYDTVAIVGSAPTFPHGVIDPIEELSEIACRHNVGLHVDCCLGGFIVPFMAKAGLPAPVVDFRLPGVTSISCDTHKYGFAPKGTSTVLYRTQELRSHQFCCVADWPGGMYCSPAVCGSKNGSVIAGAWASMVRLGEEGYVDCCRKIVQTRIRITDALSKLPYIHIIGKPTACVFAFGSNIIDIFVLNEELRSRGWVLNCLQFPSGLQFSVTLLQTVGEVADRFIEDVTEIGGRMFAEYEDATKNGRRHGAVNAKSTIYGSQQKVSDRTIIKDVLKEFLNKYYSTEH
Protein: GTP-binding protein Di-Ras2 (EC 3.6.5.-) (Distinct subgroup of the Ras family member 2) (Q96HU8)
Organism: Homo sapiens (Human)
Function: Displays low GTPase activity and exists predominantly in the GTP-bound form.
Subcellular location: Cell membrane {ECO:0000305|PubMed:12194967}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Sequence:
MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM
Protein: Probable transcriptional regulatory protein BB_0025 (O51056)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00693}.
Interaction partners:
- Bifunctional protein FolD
- Lipoprotein, putative
- Methionine--tRNA ligase
- Large ribosomal subunit protein bL19
- DNA polymerase I
- Aspartate--tRNA
Sequence:
MSGHSKWSTIKRKKGALDAKRNKIFTKLIREITIAAKIGGGDIESNPRLRVAVNKAKVANMPKDNIEKAIKKGIGGNEGVEYFEITYEAYAPYGVALMIKCLTDNKNRTSSDVKSVLAKGGGSLGTPGSVSYMFYRKGLIVYNLEKYLEDEIMEFALEVGAEDILVSNNEAEVITSPDDFDKVLSFLKTKFKEEVAEIALIPENKISLNKDQAEKIILLVEKLEDFDDVQEVIHNLEIPEELS
Protein: Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1) (Q00981)
Organism: Rattus norvegicus (Rat)
Function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (By similarity). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (By similarity). Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity). The homodimer may have ATP-independent ubiquitin ligase activity (By similarity).
Subcellular location: Cytoplasm. Endoplasmic reticulum membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Interaction partners:
- Polyubiquitin-C
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
- Lysosome-associated membrane glycoprotein 2
- Alpha-synuclein
- E3 ubiquitin-protein ligase parkin
- Gamma-enolase
- T-cell surface glycoprotein CD4
- Parkinson disease protein 7 homolog
- Ubiquitin carboxyl-terminal hydrolase
Sequence:
MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA
Protein: Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA deacylase alaX) (AlaX) (AlaXp-II) (Alanyl-tRNA synthetase domain-containing protein 1) (Q3THG9)
Organism: Mus musculus (Mouse)
Function: Functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MAFLCQRDSYAREFTTTVVSCSPAELQTDASGGKKEVLSGFHVVLEDTLLFPEGGGQPDDRGTINDISVLRVTRRGAQADHFTESPLSPGSQVQVRVDWERRFDHMQQHSGQHLITAVADLLFGLKTTSWELGRLRSVIELDSPSVTAEQVAAIEQSVNQKIRDRLPVSVRELSLDDPEVEQVRGRGLPDDHAGPIRVVTIEGVDSNMCCGTHVSNLSDLQVIKILGTEKGKKNKSNLIFLAGNRVLKWMERSHGSEKALTSLLKCGVEDHVEAVKKLQNATKLLQKNNLNLLRDLAVHTAHSLRSSPAWGGVVTLHRKEGDSEFMNIIANEIGSEETLLFLTVGDEKGAGLFLLAGPAEAVETLGPRVAEVLEGKGAGKKGRFQGKATKMSRRAEAQALLQDYVSTQSAEE
Protein: Apolipoprotein C-I (E9QDI1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Apolipoprotein Eb
- Apolipoprotein Ea
- Apolipoprotein Bb, tandem duplicate 1
- Apolipoprotein A-Ib
- Apolipoprotein A-Ia
- Apolipoprotein A-IV b, tandem duplicate 1.
- Apolipoprotein Ba.
- Apolipoprotein Bb, tandem duplicate 2.
- Apolipoprotein A-IV b, tandem duplicate 2
Sequence:
MKLYLAAAVLMLVLAVHTAEAQEEPTLEQHFTKFGTQMKEIAEDLADKTKTAFQNIEQSELGTKTRNWFNDQYEKLKQKMTETFN
Protein: DNA replication licensing factor MCM4 (EC 3.6.4.12) (A0A3B3IT92)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSSPASTPSRRGSRRGRATPAQTPRSEDARSSPSQRRRGEDSTSTGELQPMPTSPGVDLQSPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRPDLGSAQKGLQVDLQSDGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTDGVLLSSPRLESNGTILAHRNLRLPGSSHSPASASRVAGITGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTVRLL
Protein: Sorting nexin-41 (Q04053)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in proper sorting of the v-SNARE protein SNC1.
Subcellular location: Prevacuolar compartment {ECO:0000269|PubMed:14562095}. Endosome {ECO:0000269|PubMed:14562095}. Endosome membrane {ECO:0000269|PubMed:14562095}; Peripheral membrane protein {ECO:0000269|PubMed:14562095}; Cytoplasmic side {ECO:0000269|PubMed:14562095}. Note=Perivacuolar punctate structures and endosome.
Interaction partners:
- Sorting nexin-4
- Vacuolar protein sorting-associated protein 35
- Vacuolar protein sorting-associated protein 29
- Vacuolar protein sorting-associated protein 17
- Vacuolar protein sorting-associated protein 5
- Carboxypeptidase Y-deficient protein 8
- Autophagy-related protein 20
- Sorting nexin-3
- Sorting nexin MVP1
- Uncharacterized protein YKR078W
Sequence:
MDYNIFEAVHEQQSSTSDMDLSEEDNNPFVGTHHLYASGIGTTIGEARPENENSPPSSSSLPSSPAHSSSAGSSRASTSSSTSSHAVVEADAETEPFVSLSMSTTATISKFTPHDMNGTQQIQIIDAGDFKDPWGKHAIGYVILYENNKIIRRYSEFHSLRQSLTRLLPTIIIPPIPSKHSLLKYIWSPINAANDSKIISTRKKMLNSFLSNCLNIQEISNDIVFQKFLNPEFNWKDVLSSSPIIILPLNNLLAPPLSPTKPSPLHSILPIPSNSSLRNYNSIWQQHITVKSHNEISNLPTEILQNESQFTHIENLFQNYKRIITHLLKNIRSNKSHFHSLSTYFAELGAYYNAFSLENDITMPNSLRESENNSNNPMMEIISHIEKTGHSFDVIYISSEILIEKYTSILEDPINELLQFLNESFKVLNFKKLKFLQFKILERLIIEKETKLSSLTEIENQLQKINESLTRSTILTDENYKDTKAADLTFVKKDVRSLSKSSSNSSSSGHQNEIHIGASKLNYKTSTPTMNLNKLEIKQLTEQERSKQIKQLNQDLSKLKDCLSICISDMLEINNSSYNSLMHTYNHINLTIGKILKLFAASFKAWIKECLKNWKLAKLQIDEAL
Protein: Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4) (dp34) (Q9VS38)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for activated transcription of the MtnA, MtnB and MtnD genes.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 26
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 11
- Mediator of RNA polymerase II transcription subunit 30
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 8
- Mediator of RNA polymerase II transcription subunit 20
Sequence:
MSFHLSTKERLLLLIDDIEMIAKELIEQAHQKISSTELVDLLDLLVAKDEEFRKMLELAEEQAKVEEAMDQLRAKVEVHDREIQKLQKSLKDAELILSTAIFQARQKLASINQANKRPVSSEELIKYAHRISSANAVSAPLTWCIGDLRRPYPTDIEMRNGLLGKSEQNINGGTVTHQNSGMPSEQQRTLSGSAGSGSGSGAGGEVPNAFQNQFNWNLGELHMTMGASGNTVALETRAQDDVEVMSTDSSSSSSSDSQ
Protein: Putative insulin-like peptide beta-type 6 (P56173)
Organism: Caenorhabditis elegans
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Probable insulin-like peptide beta-type 3
- INSulin related
- INSulin related
- Ceinsulin-1
- INSulin related
- INSulin related
- INSulin related
- INSulin related
- INSulin related
- INSulin related
Sequence:
MHSIVALMLIGTILPIAALHQKHQGFILSSSDSTGNQPMDAISRADRHTNYRSCALRLIPHVWSVCGDACQPQNGIDVAQKCCSTDCSSDYIKEICCPFD
Protein: Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (CCAAT-binding transcription factor subunit A) (CBF-A) (Nuclear transcription factor Y subunit A) (NF-YA) (P18576)
Organism: Rattus norvegicus (Rat)
Function: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component BMAL1.
Subcellular location: Nucleus.
Interaction partners:
- Nuclear transcription factor Y subunit gamma
- Nuclear transcription factor Y subunit beta
- CCAAT/enhancer-binding protein zeta
- TATA box binding protein
- TATA box-binding protein-like 2
- TATA-box binding protein like 1
- MHC class II transactivator
- Cyclic AMP-dependent transcription factor ATF-2
- Chromatin accessibility complex protein 1
- Inhibitor of growth protein.
Sequence:
MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS
Protein: Inositol 5-phosphatase (Q54W40)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Pre-mRNA-processing factor 19
- C3H1-type domain-containing protein
Sequence:
MVLRGRAGSMTPQVNFNKLSGSGNIEERNNNQSSSQSQSSPSPSQSPSLQQNQLNSSNGMNNKVKNLLDLENYYKSIKKNITENQFEFSIKKKEKNRTLLVNLKDKSLTIFKLSKRGNKKNIKKYLISEIEKITKDKKDNKELIVFRRSKKKEMKLYFLNTERRECFYELIWMTWNNKIMPPTPLSGEEDVEEKAQYEKISIFISTWNMGDAPPPINEGLLNSWIPKSKPYDLYVIGVQECEYTPLKSKHKQTQLNQPQQQPQPQPQQAQAQQQPQQQNQSQQQYSECQEDWFGTLSEHLGHDYYKVESTSLVKMRIIIFAKKQHYYKINYIEKASIGTGIGNMYGNKGGTCISLSWWETSFCFMSSHFAAHQEKIEQRNSNYKDIIKGIKIGNKELDILNQYNYVFWMGDLNYRIGGGLFREEVLMHIKSKNIRKLLQHDQLNQQRNQEKVFIGFKEEPVGFLPTYKTLRGVENQYTEEKQRIPSWCDRILHKKLPYSHDIICLEYNSANRITTSDHVPVYGVYESYVRMPCSPNSSSCSNVKKQICQILFNDLRAECLDMVDNEERAPDAYIVFNSSAFIATEITTPHAYKNRNPIWGDLPPITPIIERQNFLETQHLFLTFYHDDKSIGHAAVPLGIGFQKEPFAFKTRITRNGLPAGTLFGSIHIVYQQISDSKLKISPNLLGKSTPDTFKFYQQSLPLPIPQINNNNNNNNNNNNNNNNNNNNNNTSVGGSGSSANNSTPPLPPKNYLNNNNNSNNNNSSNNNNNNNNNNIGYTNNANINNNGSAVSEPNSNTSTPILTPIKNYQQPQPSLQSQQLPPQPTTTTTTTTTTTTTTTTTTQTIKPLPNNQPVQLREYLSRGLSTASIELDDLTMNDNAIIQSQSSISTSSVTTINDNNNNNNNTSNNTSNNSNNADGVDDNIRPPLERQSSQLRRSV
Protein: D-threo-3-hydroxyaspartate dehydratase (D-THA DH) (D-THA dehydratase) (EC 4.3.1.27) (Threo-3-hydroxy-D-aspartate ammonia-lyase) (B2DFG5)
Organism: Delftia sp. (strain HT23)
Function: Catalyzes the deamination of D-threo-3-hydroxyaspartate (D-THA). Also exhibits dehydratase activity towards L-threo-3-hydroxyaspartate (L-THA), L-erythro-3-hydroxyaspartate (L-EHA) and D-serine.
Interaction partners:
Sequence:
MQDTLLTLDTPAAVIDLDRMQRNIARMQQRMDAQGVRLRPHVKTSKSVPVAAAQRAAGASGITVSTLKEAEQFFAAGTTDILYAVSMAPHRLPQALQLRRRGCDLKLIVDSVAAAQAIAAFGREQGEAFEVWIEIDTDGHRSGVGADDTPLLLAIGRTLHDGGMRLGGVLTHAGSSYELDTPEALQALAERERAGCVQAAEALRAAGLPCPVVSVGSTPTALAASRLDGVTEVRAGVYVFFDLVMRNIGVCAAEDVALSVLATVIGHQADKGWAIVDAGWMAMSRDRGTARQKQDFGYGQVCDLQGRVMPGFVLTGANQEHGILARADGAAEADIATRFPLGTRLRILPNHACATGAQFPAYQALAADGSVQTWERLHGW
Protein: Phototropic-responsive NPH3 family protein (F4IM54)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGVVTVPESNKQSVAAKRAFRPSSSIRHTPQWPVSDVTSDLTIEVGSATFSLHKVTKFNKLRRKKRNCFTQTRSLLQFPLVSRSGRIRKLVLESKDTNLNLAAVPGGSESFELAAKFCYGVGVQYNSSNIAALRCVAHYLEMTEDLSEKNLEARTEAYLKDSIFNDISNSITVLHSCERLLPVAEEINLVGRLVNAIAVNACKEQLASGLLKLDQSFSCGVPETAKPCDWWGRSLPILKLDFFQRVLSAMKSKGLNHDIISDILMSYARKSLQIIREPNLVKSDSDLQRKQRIVLEAVVGLLPTQANKSSIPISFLSSLLKTAIGSGTSVSCRSDLERRISHLLDQAILEDILIPANIGAMYDTDSVQRIFSMFLNLDECEYRDDDDDEEDAVDESEMAMYDFEGAESPKQSSIFKVSKLMDSYLAEVALDSSLPPSKFIALAELLPDHARVVCDGLYRAVDIFLKVHPHMKDSERYRLCKTVSCKKLSQDASSHAAQNERLPVQIAVQVLFYEQTRLKNAMTSGGGTGGSNQSQFFLFPNRSGSGMASGAISPRDNYASVRRENRELRLEVARMRMRLTDLEKDHVSMKRDFVKPQSRRRRYGMLRKLSRGLNKLNAIVLRFRSSQSVASSGKKHTEEKTNSERRFMFQKRRCHSVS