wanglab/gogpt-training-data huggingface dataset:
Protein: Leishmanolysin-like peptidase (EC 3.4.24.-) (F8WCE5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFADGLPPFNYSLGLYQWSDKVVRKVERLWDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGRQMLSPYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEKCERKLSYPDWGSGCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFCELCPPETDPPATNLTRALPLDLCSCSSSLVVTLWLLLGNLFPLLAGFLLCIWH
Protein: Alpha/beta-Hydrolases superfamily protein (At2g47630/F17A22.2) (Putative phospholipase) (O22248)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cytochrome P450 98A3
- F5F19.5 protein
- Flavone 3'-O-methyltransferase 1
- Shikimate O-hydroxycinnamoyltransferase
- 4-coumarate--CoA ligase 4
- Cinnamoyl-CoA reductase 1
- Cinnamoyl-CoA reductase 2
- Putative caffeoyl-CoA O-methyltransferase At1g67980
- 4-coumarate--CoA ligase 1
- Cytochrome P450 84A1
Sequence:
MKSSEFQYHEEYVRNSRGVELFACRWIPSSSSSPKALVFLCHGYGMECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFANVVNDCYDYYTSICAQEEYMDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKISEKVKPHPIVINLLTRVEEIIPKWKIVPTKDVIDAAFKDLVKREEVRNNKLIYQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKALYEKASTRDKTLKLYPGMWHALTSGEPDCNVDLVFADIINWLDLRTADPASLTVTPIRVGNTTSVQRVTTVNGVSNGHRRPKRPFFNLLCGLNRGRLVPRSTV
Protein: Iron-sulfur cluster co-chaperone protein HscB homolog (AtHscB) (Q8L7K4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Co-chaperone required for the assembly of iron-sulfur [Fe-S] clusters in both mitochondria and cytosol. Required for the activity of iron-sulfur proteins such as aconitase and succinate dehydrogenase. Involved in iron homeostasis and may take part in the control of iron translocation from roots to shoots.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:19865480}. Cytoplasm, cytosol {ECO:0000269|PubMed:19865480}.
Interaction partners:
- Iron-sulfur cluster assembly protein 1
- Iron-sulfur cluster assembly protein 2
- Iron-sulfur cluster assembly protein 3
- Heat shock 70 kDa protein 9, mitochondrial
- Frataxin, mitochondrial
- Heat shock 70 kDa protein 10, mitochondrial
- Cysteine desulfurase, mitochondrial
- NifU-like protein 5, mitochondrial
- NifU-like protein 1, chloroplastic
- NifU-like protein 4, mitochondrial
Sequence:
MKKTKTMVASISTLIRRTYPSTNQCNSLATIQSQTQLPRESLQHHSSAEGRLRFSGRVFCSESGAGCWNCGEKAAFLFCNSCRSIQPVDDSVDYFQIFGLEKKYEIDPGSLEGKYKDWQKKLHPDLVHNKSKKERDYAAEQSAKVTEACRTLTKRLSRAMYIMKLNGVNVNEEETITDPTLLMEIMELREAISEADDSTSLNQIRSQVQEKLKQWSDSFVEAFESQKFDDAVKCIQRMTYYERACEEILKKL
Protein: Leucine-rich repeat-containing protein 51 (Q08C25)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MFGSSVDFSFKEINTISDVLSDVPNSSAHPPKRDSKKKFISMSFRLNNNSIKDLTGLMDTLSALFSEPTRLAWLDLSFNEIKHIDSVLTQLKELRLLYLHGNNIQELSEVDKLAVLPSLHTITLHGNPIVSERDYRAHLIAMLPHVKMIDFSAVTKQERELTSVWQKSKNTHKSTGYSKSD
Protein: DNA-directed RNA polymerase subunit Rpo6 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit K) (B8YB61)
Organism: Saccharolobus shibatae (strain ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12) (Sulfolobus shibatae)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00192, ECO:0000269|PubMed:22848102}.
Interaction partners:
Sequence:
MGLERDGILSQDLHFNEVFVSLWQNKLTRYEIARVISARALQLAMGAPALIDINNISSTDVISIAEEEFKRGVLPITIRRRLPNGKIILLSLRKS
Protein: Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (A0A3B3IRT8)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115, ECO:0000256|RuleBase:RU368074}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115, ECO:0000256|RuleBase:RU368074}.
Interaction partners:
Sequence:
MRLLPRLLLLLLLVFPATVLFRGGPRGLLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLVEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTVIEREDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDDID
Protein: Vps54_N domain-containing protein (Q18602)
Organism: Caenorhabditis elegans
Interaction partners:
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar protein sorting-associated protein 53 homolog
- Vacuolar protein sorting-associated protein 52 homolog
- Vacuolar protein sorting-associated protein 54
- EARP-interacting protein 1
- Dymeclin
- Trans-Golgi network integral membrane protein 2
- Putative syntaxin 6
- ADP-ribosylation factor-like protein 5
- RUN domain-containing protein
Sequence:
MDRFKEQLAKTVNQIGEQFSSDSDVKVLLDNMNEKVMSSYDAPSCSESPPIAPESNSQNSTPRRVKSKISEEDDVINSIDAAYFIDNDEFDAIDYELKKLCDIEMCYEDIQRERFRLKSQHTVVSKKISTLIMQKSSSYTAQVGEMEKIRDEVGSVINEILTIRKALALATSQTRTCLGLIAYKNKKIVLNQLKMTLTTIKGFHETEQHIRETIEEGNFPLAIQMLIETQIKAGGYAHFTCVNEVISKLAGMSCLLEAELSAQLSTIAVVFDSEKYRFVYTAYEMLEKTEQVAEKLLTAFVEAIETTTSAVVLSKLKEEDRLEDSSYTSLCLKLDSEQASITFREMGFVLCRSFQAFHKILNFHSSESASEASQSIYKQLLASRTEVFLAATRRLQVLVESRDFVSLKFEHILDIVDTINRFNNIGKTYFASTHHQKLAESIEKRTETYFDRYHTERMEELSMFFENESFALCPVPFQFTIFDLQDFEFLKESVRIESSPKSREESENSEEETVELIGNDWQNPFCQAAIRSRLQSSYSQKSERSYSTSSAATEIQNENYNPNLTKQESFSEDPLDEPSGVPPPNLCNTALNLLRFFGRYLRMTALLPTLCSKSAPAIIDLYEFFFASMCHMFGSEGAEFVGRIPRLVACLDGISRKFTKDEKANSPFRKVFQKDGDFLSGKMYPSLSPAVQIAFIDNLYGACERIIAVNSIEFVARQLDLIRPVIESLLLEDTREHLSTILDAFYTQVLPCQADARILIVDASASRSLRLKSLIDSVTSVKWDIGELRSEHNAYVDLLVQDYELFSIRITAIKETAPVNLSEAMEKFFWERAIYYSFKALVQGYGDGGKCSTEGRALMQLDFQMILMKLEPLCGIKPVPHASFVDGYIKAYYLPENGLEQWIKTHSVRGFSNLINYFPEILQEYSSKQLSSLLGAAAHVSKKARLRILDALKD
Protein: Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain) (Proteasome subunit alpha-1) (alpha-1) (P60900)
Organism: Homo sapiens (Human)
Function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9QUM9, ECO:0000269|PubMed:12181345}. Nucleus {ECO:0000269|PubMed:12181345, ECO:0000269|PubMed:34711951}. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9 (PubMed:34711951). Colocalizes with TRIM5 in cytoplasmic bodies (By similarity). {ECO:0000250|UniProtKB:Q9QUM9, ECO:0000269|PubMed:34711951}.
Interaction partners:
- Proteasome subunit beta type-2
- 26S proteasome non-ATPase regulatory subunit 1
- 26S proteasome regulatory subunit 4
- Proteasome subunit beta type-8
- Proteasome subunit beta type-9
- 26S proteasome non-ATPase regulatory subunit 14
- Proteasome subunit alpha type-3
- Proteasome maturation protein
- 26S proteasome regulatory subunit 10B
- Proteasome subunit beta type-3
Sequence:
MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD
Protein: PDZ domain-containing protein (Q8BRB8)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEKEEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVMQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTHEVFSSRSSEVVLSGDDEDYQRIYTTKIKPRLRSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGVKDIDITSPEFMIKIPRHEVTEISNTDVETQPGKTVIRLPSGSGPASPTTGSAVDIRAGAISASGPELEGAGHSKFQVTVPGAKVGSLDVNVKAKGLDLGGKGGIRVPGVDVSSSLGAGSVEVQAPSLQSGDIGKIKIPTMKVPKFGVSAGLDGQIPEVGLSVSAPESSVGHKGDKPGLAIGGNIQAPHLEVNPSSVNIEGLEGKLKGPQITGPSLEGDLGLKGTKLQGNIGMDACASKIEGSITGPSVEIGTPDVDVHGLGGKLNMPKMKVPKFSASGSKGEGIGLDVALPTGEVTLPGVSGDVSLPEIATGGLEGKMKGAKVKTPEMIIQKPKISMQDVDLSLGSCKL
Protein: ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK) (P56559)
Organism: Homo sapiens (Human)
Function: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.
Subcellular location: Cell projection, filopodium. Cell membrane. Cytoplasm.
Interaction partners:
- Jun dimerization protein 2
Sequence:
MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR
Protein: Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53) (P62142)
Organism: Rattus norvegicus (Rat)
Function: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62140}. Nucleus {ECO:0000250|UniProtKB:P62140}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:P62140}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62140}. Note=Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles. {ECO:0000250|UniProtKB:P62140}.
Interaction partners:
- Protein phosphatase 1 regulatory subunit 12A
- Protein phosphatase 1 regulatory subunit
- Protein phosphatase 1 regulatory subunit
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- WD repeat-containing protein 82
- Eukaryotic translation initiation factor 2 subunit 1
- Protein phosphatase 1 regulatory subunit 7
- Protein phosphatase 1 regulatory subunit 14A
- Glycogen [starch] synthase, muscle
Sequence:
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR
Protein: Aquaporin-4 (Q6AZD2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004415}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004415}. Cell projection {ECO:0000256|ARBA:ARBA00004316}. Endosome membrane {ECO:0000256|ARBA:ARBA00004608}.
Interaction partners:
- Aquaporin
- Transient receptor potential cation channel, subfamily V, member 4.
- Aquaporin
- Caveolin
- Aquaporin 7
- Aquaporin-3
- Aquaporin 9b
- Aqp8a protein
Sequence:
MTSCGALDTFRRCVSSCSCNNSIMAAFKGVWTQEFWRAVSGEFLAMIIFVLLSLGSTINWGAKQENPPPADLVLISLCFGLSIATLVQCFGHISGAHINPAVTVAMVATRKLSLAKGVFYLLAQCLGAVVGAAILYGVTPASVRGGMGVTSVNEEISAGHAIVIELIITFELVFTVFATCDPKRNDLKGSAALAIGLSVCIGHLFAIPYTGASMNPARSFGPAVIMVKWQDHWVYWVGPLIGGILAAAVYEYLFCPDPDLKRRYADVLSKSPFQMEPYRVVDTDSYPSDQAQLMAKQAALRVLDLEKKERESTGEVLSSV
Protein: Interleukin 9 receptor (A0A8I6AHK3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
PACGRSQPLVGCTVEGAAVKQVSWFLIYSCVCSCVCWGVSVPAQEGGRKAGTFTCFSNSVFRIDCHWSAPEPGSRAWLLFTSNQVTDIKHKCTFWDSRCTLVLPKEEAFLPFDNFTITLHRCVMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGISFGLEPLITSLSYELAFKRQEEAWEQARLKDRIVGVTWLVLEAIELNPDTIYEARLRVQMALESYDDKTEGEYYKSHWSEWSQSVSFPSPRRKTQGLLIPRWQGSASILVAVPIFLLLTGLIHFLFRLSPKVKRIFYQNVPSPEAFFHPLYSVYHGDFQTWIGARRAGPQARQDGASAPSGDSESSIWEAIATLTYSPACSVQFPSLKWEATAPGFPGPPGSELVLPAGCLELEGQPSAYLPQEDWAPLGSARPPPLDSDSGSSDYCMLDCREEYDLSVFPEHTLSPEFTLAQPVALAVSSRA
Protein: Arginine vasopressin receptor 1A (Vasotocin receptor) (A8CWP8)
Organism: Gallus gallus (Chicken)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU046427}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU046427}.
Interaction partners:
Sequence:
MRLGGGGGSPRAAGPPGNGSRWRGAAEDGSSPSPEAWSGAPNGSAGDWDPFGRDEELAKLEIAVLAVTFAVAVLGNGSVLLALRRTPRKASRMHLFIRHLSLADLVVAFFQVLPQLCWEVTHRFHGPDGLCRVVKHLQVFGMFASAYMLVAMTADRYIAVCHPLKTLQQPTKRSYAMIAAAWALSLLLSTPQYFIFSLSEVERGSRVYDCWAHFIMPWGPRAYITWITGGIFVAPVLILATCYGFICFRIWRSARGRARPGEAAGGGPRRGLLLAPCVSGVKTISRAKIRTVKMTFVIVSAYVVCWAPFFTIQMWSVWDQHFPWVDSENTATTVTALLASLNSCCNPWIYMFFSGHLLQDCVQSFPCCQKIKQTLSKEDSNSNSRRQTSFTNNRSPTHSLNTWRESPHSKSTSFIPVPT
Protein: steroid 11beta-monooxygenase (EC 1.14.15.4) (Q3TR45)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
MALRVTTDVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHSVGKTQIVFVTLPEDVEKLYQVESTHPCRMPLESWIVHRELRGLGRGVFLLNGPEWYFNRLQLNPNVLSPKAVQKFVPLVDGIARDFVDNLKKKMLESVHGSFSMDFQSSVFNYTIEASHFVLFGERLGLIGRDLSPDSLKFLHTLHSMFKTTTQLLYLPRSLTRWTSTRVWKENLESWDFISEYVTKCIKNVYRELAEGRPQSWSVTAELVAERTLSMDAIQANSMELIAGSTDTTSTPLVMTFFELARNPDVQQALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGTFLERILSSDLVLQNYHVPAGTVLNVNLYSMGRNPAVFPRPERYMPQRWQRKRSFKHLAFGFGVRQCLGRRLAEAEMMLLLHHVLKSFHVETQEKEDVRMAYRFVLMPSSSPLLTFRPVN
Protein: MLLT10 histone lysine methyltransferase DOT1L cofactor (Q5JT35)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPEQHQAFLYQLMQHHHQQHHQPELQQLQIPGPTQIPINNLLAGTQAPPLHTATTNPFLTIHGDNASQKVARLSDKTGPVAQEKS
Protein: Uncharacterized protein (Q582Y4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MREMPQPQSSCIGCRIKTHNSAGIGARPLHLPEPVDSAEGNRHAIKVLLLYMNHMEVTMSSLTAGASIFSLLWLIIFVAWEKESVEDSLLLYIAITHSYEGAAFQFLFILLLVASLTPFAWRFANKQCAEEVSDRCPAGINPLPQHLFRREGIIDGARFPISCNPVTSHVDTCSNAATVVAPGLRCDVRHSNAGVKTQSHLQQHKDISHGGDVAPNAAAAASWEVEVSLKSPWMLLLKPIVPLYITCTALTVAQIALTEGWDAAKLQKVAAADAASLRIVLLTVISVRAGLMSLAVLCNLFRPSKEMKVYFLS
Protein: Misfire, isoform F (B7Z0E5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Protein sneaky
- FI18813p1
- FI18412p1
- Synaptotagmin 1
- Cadherin-99C
Sequence:
MSYMDDCFAGAPQEFLICITVHKAAQVGVTTGELYVRISLDKMTKSTKSFPNTENPFFNEYFVFEFHCTLTELLRLTILFELKKHMTYKKNVVVGELLVDLHSVWNQSNHGYFKKWGRLEAPIGENQTLENAVAPHGYLQLDLAIVSQHSPVSYALGSEEQDTQNLNKWTVDHDFDDIEKNLLTNVNIFAPSNIRYFVAFYRGYFIKQSNYMIQVSFAGFNGKTPVVKNTTTPVWNYEINFAWMYPSVAQRFLILIFAHEHLQWKCVAEFELCLEEIAFNGTPSLGPTYLHLYDPVNPMIYVGRLLMELRSEMLTDSQPTHTLSSKTVPGLDETRFWHDDVYLIEFLPLMGHHILTSGTAYKISARLAEHTSNVLEGQLRTPLDRFKSAMNSKNFRREAPFQSCMFRVRLPDNRAKYESDFFMLDIVNYMRSELDTFKLFQRKYPLQDDEQAKCLKVIVNNILTRIKEGLDAHRFDHDVQPQRTTWDINRQLYLLDYFAKLPLELQNLKQKLRSCFLEHLDTSIGDVVNELQRLVAEIGSLSSMARTQDEWPELVLSLSASGKDVGVCRLNAKLFLNLRNQDADQDQETLCWRLKSFSFKSAGCSHTCPNCGCTTAIVSGCLSIVVERERKRFLAVVNKEWANIEPMLWQLNPEQTHFLCHVYIHQAKVRPGGEKKNICDSHLRVLFADQACETYTSPGTLSPIWNAVITFNWVSLPGGIGLYLKNPPLLSLEFYNSERSLPEDLVGMGSVAMSVISEDRASDSNWEDAGVFGCSKNPLRKLQRLKYLTPPPLKWVPIARKGTLQAEVLMSAEIIQISMESLTTGQNDKKEPQLATGIPMAIRPTMQNFVLEVFFVGLRNYSKSSMSSAGKRKINLMMGDLVLSSGPSTARIRNSINFLVAYASGVVSLPDQQDYWPAIIATDVLLSGFSSESILGAALIPNSSNFLQRDRTLKCVFKKEQEAAEASTTVSVDEDDEDEEEELEWEEEETKPSRISSWWMRLLFAFGLRPAPYANRHALRFHDDLDDHELVEEREFTWWTKFYNSMYWSAAEMCHEHKHRLVIYYEELEKQAQFGYLQDWAVPVQLVHGVKFKKHGPPKEDIYATLKLQLKLTPCQCPVLEDPGGGGDMVRNMSNPIHPRHQSTLQSLGETVKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKIKDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYYYGNVIEVDGMLFGDETLISKDEELQERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSPIDITPVPPADFEVRVVVKNLVGIQAGDKNIFGKLMSDVYVIGWCEDEDKRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGLLEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPYPKKRKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGKMQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHILWPVIRKYVLWTLLILIVILGLVLFFSNLPAKLMTIPLE
Protein: Vesicular integral-membrane protein VIP36 (Glycoprotein GP36b) (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36) (Q12907)
Organism: Homo sapiens (Human)
Function: Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity).
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:10444376}; Single-pass type I membrane protein {ECO:0000269|PubMed:10444376}. Golgi apparatus membrane {ECO:0000269|PubMed:10444376}; Single-pass membrane protein {ECO:0000269|PubMed:10444376}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:10444376}; Single-pass type I membrane protein {ECO:0000269|PubMed:10444376}.
Interaction partners:
- Multiple coagulation factor deficiency protein 2
- Transmembrane emp24 domain-containing protein 2
- Transmembrane emp24 domain-containing protein 10
- Protein ERGIC-53
Sequence:
MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY
Protein: NADH-quinone oxidoreductase subunit C/D (EC 7.1.1.-) (NADH dehydrogenase I subunit C/D) (NDH-1 subunit C/D) (Q608X9)
Organism: Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Function: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01359}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01359}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_01359}.
Interaction partners:
- NADH-quinone oxidoreductase subunit E
- NADH dehydrogenase I, L subunit
- NADH-quinone oxidoreductase subunit N
- NADH-quinone oxidoreductase subunit K
- NADH-quinone oxidoreductase subunit I
- NADH-quinone oxidoreductase
- NADH-quinone oxidoreductase subunit H
- NADH-quinone oxidoreductase subunit A
- NADH-quinone oxidoreductase subunit M
- NADH-quinone oxidoreductase subunit B
Sequence:
MAAPTTEHAETIVPALCRRFGGETFVQQTTADGISTLWLPARILVETIRYLRSEIDRPYALLFDLTAVDERVRKHRDGMPASAYTVVYHLVSLERNADVRLKIALPETDPALPSIVAVCPAANWYEREVWDMFGIRFDGHPNLRRLIMPPTWQGHPLRKDHPARATEMEPFSLPDDVQQQEQEALRFVPEEWGMQRQSEDTDFLFLNLGPNHPSVHGVFRVALQLDGEEIVDAVPDIGYHHRGAEKMGERQSWHSYIPYTDRIDYLGGSMNNLPYVMAVEKLAGIEVPERARVIRVMISEFYRIASHLLFYGTFAQDVGQMSPIFYMFIDRERVFEIIESFTGARMHSSFFRIGGVAMDLPEGWDRLIREFIAYFPRRLAEYDKAVMANKLIQRRTRGIGAYTTTEAIDWSVTGAGLRATGLPWDYRKARPYSGYENFEFDVPTGTNGDCYDRCAVRVEEMRQSLRIIEQCVEHMPSGPYKAEHPLTTPPPKERTMHDIETLIQHFLSVSWGPVIPPGEVCVTIEATKGLNGYYLTSDGGTMSYRTRIRTPSFPHLQMIPLMSRGMMVADLIAILASIDFVMADVDR
Protein: High mobility group B protein 6 (Nucleosome/chromatin assembly factor group D 06) (Nucleosome/chromatin assembly factor group D 6) (WRKY transcription factor 53) (AtWRKY53) (WRKY DNA-binding protein 53) (Q9SUP7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
- WRKY transcription factor 18
- WRKY transcription factor 6
- E3 ubiquitin-protein ligase UPL5
- Mitogen-activated protein kinase kinase kinase 1
- Protein S40-3
- Probable WRKY transcription factor 53
- Probable WRKY transcription factor 46
- Probable WRKY transcription factor 70
- High mobility group B protein 12
- Kinetochore protein NDC80 homolog
Sequence:
MATNADPAPTKKPRNSRKALKQKNELVETPPSPVSVKGKSAKSFEQDLMEMQTMLEKMKIEKDKTEELLKEKDEILRKKEEELETRDAEQEKLKVELKKLQKMKEFKPNMTFACGQSSLTQAEQEKANKKKKKDCPETKRPSSSYVLWCKDQWTEVKKENPEADFKETSNILGAKWKSLSAEDKKPYEERYQVEKEAYLQVIAKEKREKEAMKLLEDDQKQRTAMELLDQYLNFVQEAEQDNKKKNKKEKDPLKPKHPVSAFLVYANERRAALREENKSVVEVAKITGEEWKNLSDKKKAPYEKVAKKNKETYLQAMEEYKRTKEEEALSQKKEEEELLKLHKQEALQMLKKKEKTDNLIKKEKATKKKKNENVDPNKPKKPASSYFLFSKDERKKLTEERPGTNNATVTALISLKWKELSEEEKQVYNGKAAKLMEAYKKEVEAYNKKSAATTSS
Protein: Leukocyte-specific transcript 1 protein (Protein B144) (O00453)
Organism: Homo sapiens (Human)
Function: Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Subcellular location: Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
Interaction partners:
- Lymphotoxin-beta
- Allograft inflammatory factor 1
- TYRO protein tyrosine kinase-binding protein
- Natural cytotoxicity triggering receptor 3
- Phosphatidylserine lipase ABHD16A
- Lymphotoxin-alpha
- Ras-specific guanine nucleotide-releasing factor RalGPS2
- NF-kappa-B inhibitor-like protein 1
Sequence:
MLSRNDDICIYGGLGLGGLLLLAVVLLSACLCWLHRRVKRLERSWAQGSSEQELHYASLQRLPVPSSEGPDLRGRDKRGTKEDPRADYACIAENKPT