wanglab/gogpt-training-data huggingface dataset:
Protein: Interleukin-1 (Q90W84)
Organism: Dicentrarchus labrax (European seabass) (Morone labrax)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Lysosome {ECO:0000256|ARBA:ARBA00004371}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
Interaction partners:
Sequence:
MESEMKCNMSEMWRSKMPQGLDLEITHHPLTMRRVVNLIIAMERLKGFSSETLMSTEFRDENLLNIMLESIVEEKIVFERGTTPTAQYSKRREVQCSVTDSEKRSLVLVPNSMELHAVMLQGGSDRCKVQLNMSTYLDRTPSAEAQTVALGIKGTNYYLSCHKDGEEPTLHLEVVDKASLANITSDSDMVRFLFYKQDSGLNISTLTSVPFSNWYISTAEENNRPVQMCQESARRHRAFNIDNLKVDPTTEDQVCPLLNGQ
Protein: 5-hydroxytryptamine receptor 3B (5-HT3-B) (5-HT3B) (Serotonin receptor 3B) (Q9JJ16)
Organism: Rattus norvegicus (Rat)
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:O95264}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O95264}; Multi-pass membrane protein {ECO:0000255}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. {ECO:0000250|UniProtKB:O95264}.
Interaction partners:
- 5-hydroxytryptamine receptor 3A
- Glutamate receptor ionotropic, kainate 1
- Glutamate receptor ionotropic, NMDA 2C
- Glutamate receptor 3
- Glutamate receptor 4
- Glutamate receptor ionotropic, kainate 2
- Glutamate receptor ionotropic, kainate 4
- Glutamate receptor 2
- Noelin-3
- Glutamate receptor ionotropic, NMDA 2B
Sequence:
MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSMWYREVWNDEFLSWNSSLFDDIQEISLPLSAIWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNQEDIENDKRSFLNDSEWQLLSVTSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTSLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSEQERPLMCLRGDSDANESRLYLRAPCAEDTESPVRQEHQVPSDTLKDFWFQLQSINNSLRTRDQVYQKEVEWLAILCHFDQLLFRIYLAVLGLYTVTLCSLWALWSRM
Protein: Tubulin beta-7 chain (Beta-7-tubulin) (Q6VAF5)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Classical arabinogalactan protein 5
- Protein RADIALIS-like 6
- Fasciclin-like arabinogalactan protein 12
- Fasciclin-like arabinogalactan protein 1
- Tubulin-specific chaperone A
- Tubulin-specific chaperone A
Sequence:
MREILHVQAGQCGNQIGGKFWEVVSDEHGIDPKGNYVGTSRVQLERVNVYYNEASGGRYVPRAVLMDLEPGTMDSLRTGPHGQLFRPDNFIFGQNGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCACLQGFQICHSLGGGTGSGMGTLLISKIKEEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENGDECMVLDNEALYDICFRTLKLTNPSFGDLNRLISTTMSGATCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSSSSQQYRALTIPELTQQMWDARNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPTGLTMSSTFMGNSTSIQEMFRRVSEQFTVMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAVADDNDEDYEDEAMEN
Protein: Sporulation-specific protein 2 (Q08646)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential for sporulation and seems to have a role at the time of, or after, initiation of nuclear division. Appears to have a role in outer spore wall formation.
Subcellular location: Spore wall {ECO:0000269|PubMed:12073037}.
Interaction partners:
- Sporulation-specific mitogen-activated protein kinase SMK1
- Outer spore wall protein 1
- Sporulation-specific protein 22
- Sporulation-specific protein 74
Sequence:
MYKNYYSNTEVYKKHKDSGSLRKKALRSRRSSFFSFFNDSSSSNGNEFIGFRRFAKAYLFGREIGSCGTDSYTPVGANVNKRRLKKEDKNDQQLWKRQHHSQGCFFPIDDDSNKQTEAAVNKFYENGEYVNQDLIFKGKVYSEESEVVDEKTAGSQNPALLKTRSISLNDIPRGTGISSVLSQVRGGSLERIIVYRYDTPERSLHKVDLFFLNYEGAQSFMRYAKTNIFKVNGVQLKPEWIFLESTYENIMKEQSVNRIIEEEKFISRCLIVKKSSTTAMPNKSNLNKGQTLENIDIQELEKDFQNFGEVLEITPIVSRKLCVSIFFYDISSAMRAMEEYEQKGSYLYNKYFKTWTIWYGKDITDQPCIDL
Protein: Zinc finger protein 251 (Q3V362)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLSFQGETPLTFQDVAVYFSRAEGQQLSPQERALYRDVMLENYGNVASLGFPGPKPELISQLEQEEELWVLDLLGAEEPEVLRRCQTDSEIEAEKELSILNQKCFEEVKTPEFISPKFPRAYSQASEPQEACAHEGQGDGSHGSSATQGLKSIAKKDAAVCREQFPKNAQTSVFDKHLNPSQSVVTVQRNKAGQRIFKCDICNKTFKYNSDLSRHRRSHTGEKPYECGPCGRAFTHSSNLILHQRIHTGNKPFKCEECGKTFGLNSYLRLHQRIHTGEKPFGCKECGKAFSRSSSLIQHRIIHTGEKPYKCDECGKAFSQSPQLTQHQRIHTGEKPHGCTWCGKAFSRNASLIQHQRIHTGEKPHKCAQCGKAFSQSSSLFLHHRVHTGEKPYVCGECGRAFGFNSHLTEHVRIHTGEKPYVCGECGKAFSRSSTLMQHRRVHTGEKPYQCAECGKAFIQSSQLTLHQRVHTGEKPYECGLCGKAFSRRSALTQHQRVHMGENPQEFECGPDFVYDSSHLSAGERHGRAFSHSAKLVLQWTIRSDEKSRGCHECGKTYSTSSQSMDYQKSQAGEKPYKCQECGGKAGSGVSPLTPHHVTRVGEKPQLKDGSERYLIQIKKIF
Protein: Protein ABHD13 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 13) (Abhydrolase domain-containing protein 13) (Q7L211)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MEKSWMLWNFVERWLIALASWSWALCRISLLPLIVTFHLYGGIILLLLIFISIAGILYKFQDVLLYFPEQPSSSRLYVPMPTGIPHENIFIRTKDGIRLNLILIRYTGDNSPYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLLLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKIFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVVKSHSPEEMAKTSSNVTII
Protein: Metalloaminopeptidase (A0A1D8PJE0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Csp37p
- Autophagy-related protein 8
- Carboxypeptidase
Sequence:
MSNIDDILLGISESLKQLQKASQEKPIEQTQPVQIQNLEVNSTKKFTDDYYSKIADDYIEFTYKNPTIYHVVNFFKSQLESKGFTYLPESKSWADLKAGKYFTTRNGSSLAAFVVGKDWQASKGVGAIGSHIDSLTTVLKPNSTKAKVDGYELLGVAPYAGTLGSVWWDRDLGIGGRLLVKDGKGKVSQHLVDSTPHPIAHIPTLAPHFGAPANGPFNTETQAVPVVGFSGENDKEEEQPTEEEKNAPLYGKHPLKLLRYIAKLANVSVGDILQWDLQLYDVQKGTKGGLNKEFVFAPRVDDRVCSFAALNALIDSTVDNNLAEDSFSIVGLFDNEEIGSLTRQGARGGLIELVVDRVLSSNFYNPEVLDIQESLRLTYANSIVLSADVNHLFNPNFPGVYLEHHKPLPNIGVTLSLDPNGHMATDSIGLALAEELAKKNGDKVQYFQIRNDSRSGGTIGPAISTSTGARTIDLGIPQLSMHSIRATLGSKDIGLGIKFFYGFFKNWRDVYDNFADL
Protein: SPI-1 type 3 secretion system needle filament protein (T3SS-1 needle filament protein) (P41784)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Required for invasion of epithelial cells.
Subcellular location: Secreted {ECO:0000269|PubMed:12754250}. Cell surface {ECO:0000269|PubMed:12754250}.
Interaction partners:
- Surface presentation of antigens protein SpaM
- SPI-1 type 3 secretion system secretin
- Protein PrgH
- Protein PrgJ
- Lipoprotein PrgK
- Cell invasion protein SipD
- Surface presentation of antigens protein SpaN
- Surface presentation of antigens protein SpaP
- SPI-1 type 3 secretion system ATPase
- Surface presentation of antigens protein SpaK
Sequence:
MATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR
Protein: Flocculation protein FLO11 (Flo11p) (Flocculin-11) (KpFLO11) (C4R2D7)
Organism: Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Function: Homophilic binding protein that enables kin discrimination in heterogeneous yeast populations by mediating homotypic cell-cell interactions during flocculation, a reversible and asexual process in which cells adhere to form aggregates (flocs).
Interaction partners:
Sequence:
MVSLRSIFTSSILAAGLTRAHGSSGKTCPTSEVSPACYANQWETTFPPSDIKITGATWVQDNIYDVTLSYEAESLELENLTELKIIGLNSPTGGTKLVWSLNSKVYDIDNPAKWTTTLRVYTKSSADDCYVEMYPFQIQVDWCEAGASTDGCSAWKWPKSYDYDIGCDNMQDGVSRKHHPVYKWPKKCSSDCGVEPTTSDEPEEPTTSEEPVEPTSSDEEPTTSEEPTTSEEPEEPTTSDEPEEPTTSEEPEEPTTSEEPEEPTTSEEPTTSEEPEEPTSSDEEPTTSDEPEEPTTSDEPEEPTTSEEPTTSEEPEEPTTSSEEPTPSEEPEGPTCPTSEVSPACYADQWETTFPPSDIKITGATWVEDNIYDVTLSYEAESLELENLTELKIIGLNSPTGGTKVVWSLNSGIYDIDNPAKWTTTLRVYTKSSADDCYVEMYPFQIQVDWCEAGASTDGCSAWKWPKSYDYDIGCDNMQDGVSRKHHPVYKWPKKCSSNCGVEPTTSDEPEEPTTSEEPEEPTTSEEPEEPTSSDEEPTTSEEPEEPTTSDEPEEPTTSEEPEEPTTSEEPEEPTTSEEPEEPTTSDEEPGTTEEPLVPTTKTETDVSTTLLTVTDCGTKTCTKSLVITGVTKETVTTHGKTTVITTYCPLPTETVTPTPVTVTSTIYADESVTKTTVYTTGAVEKTVTVGGSSTVVVVHTPLTTAVVQSQSTDEIKTVVTARPSTTTIVRDVCYNSVCSVATIVTGVTEKTITFSTGSITVVPTYVPLVESEEHQRTASTSETRATSVVVPTVVGQSSSASATSSIFPSVTIHEGVANTVKNSMISGAVALLFNALFL
Protein: SPARC-related modular calcium-binding 1 (SPARC-related modular calcium-binding protein 1) (Secreted modular calcium-binding 1) (E7EDQ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- Eva-1 homolog A, regulator of programmed cell death.
- Protein eva-1 homolog A
- Spalt-like transcription factor 2.
Sequence:
MPSSLHLCVQWLIGDRESPCSTSCSRSHGKPVCGSDGRSYDTNCDLERAKCRDRTLTLAHRGRCKGKNWVRIDQPLLVPTLVSEVKELTGMKEAGQTKCRTERIQALEQAKKPQESIFIPECNDDGTFAQVQCHTLTGYCWCVTTDGKPVSGSSVQNKTPVCSGNFREFMGTHAGTSGLSGSVTDKPPGPPSSGKKVSFRFFLTLNPDDGSKPTPTMEPHVVPEEITAPTLWIKQLVYKENKQNSSNSRKSEKVPSCDQERQTAQDEARQNPREAIFIPDCGLQGLYKPVQCHQSTGYCWCVLVDTGRPIPGTSARYKKPECDSAARSRDTEMEDPFRDRDLTGCPEGKKVEFITSLLDALTTDMVQAINSPTPSGGGRFVEPDPSHTLEERVVHWYFAQLDNNGSHDINKKEMKPFKRYVKKKAKPKRCARKFTDYCDLNKDKTISLQELKGCLGVNKEG
Protein: 60S acidic ribosomal protein-like protein (60S acidic ribosomal-like protein) (Q1PEH0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein eL42z/eL42y
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Large ribosomal subunit protein uL18z
- Large ribosomal subunit protein eL29z
- Large ribosomal subunit protein eL29y
- Large ribosomal subunit protein eL21x/eL21w
- Large ribosomal subunit protein eL21z/eL21y
Sequence:
MATGELACTYAALLLHDHVTAEKDVNIGENSQFEH
Protein: Cytochrome P450 (EC 1.14.14.-) (Q9JKY7)
Organism: Mus musculus (Mouse)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU368047}. Microsome membrane {ECO:0000256|RuleBase:RU368047}.
Interaction partners:
- Cytochrome P450 7A1
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 3
- Steroid 17-alpha-hydroxylase/17,20 lyase
- NADPH-dependent 3-keto-steroid reductase Hsd3b5
Sequence:
MRLPTGAELWPIAIFTVIFLILVNLMHWRQRWTAHYPPGPMPWPVLGNLLHMDFQNMPAGFQKLRGRYGDLFSLQLASESVVVLNGLTALREALVKHSEDTADRPPLHFNDLLGFGPRSQGIVLARYGPAWRQQRRFSVSTMHHFGLGKKSLEQWVTEEARCLCAAFADHTGHPFSPNTLLDKAVCNVIASLLYACRFEYDDPRFIRLLGLLKETLKEEAGFLPMFLNVFPMLLRIPGLVGKVFPGKRAFVTMLDELLAEHKTTWDPTQPPRDLTDAFLAEVEKAKGNPESSFNDENLRTVVGDLFSAGMVTTSTTLSWALMLMILHPDVQRRVQQEIDEVIGQVQCPEMADQARMPYTNAVIHEVQRFADILPLGVPHKTSRDIELQGFLIPKGTTLITNLSSALKDETVWEKPLCFHPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSISVPDGQPQPSDHGVFRALTTPCPYQLCALPR
Protein: Beta-catenin 2 (Catenin, beta 2) (Q8JID2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MASQADLMELDMAMEQDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDLDNQVLYEWEQGFSQPFTPEQVADLDGQYAMTRAQRVRAAMFPETLDESVPMASTQFDSAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLASDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIESLVRTVLRAGDREDITEPAVCALRHLTSRHQDAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAPGETLAYRADEPSYRSFHSGYAAEALGMEGLLEQEMSHHPGAEFPVEALPDLAHAQDLMDGLPNTDSNQLAWFDTDL
Protein: Stromelysin-3 (SL-3) (ST3) (EC 3.4.24.-) (Matrix metalloproteinase-11) (MMP-11) (Q02853)
Organism: Mus musculus (Mouse)
Function: May play an important role in the progression of epithelial malignancies.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000305}.
Interaction partners:
- Furin
- Stromelysin-2
Sequence:
MARAACLLRAISRVLLLPLPLLLLLLLLLPSPLMARARPPESHRHHPVKKGPRLLHAALPNTLTSVPASHWVPSPAGSSRPLRCGVPDLPDVLNARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVREQVRQTVAEALQVWSEVTPLTFTEVHEGRADIMIDFARYWHGDNLPFDGPGGILAHAFFPKTHREGDVHFDYDETWTIGDNQGTDLLQVAAHEFGHVLGLQHTTAAKALMSPFYTFRYPLSLSPDDRRGIQHLYGRPQMAPTSPAPTLSSQAGTDTNEIALLEPETPPDVCETSFDAVSTIRGELFFFKAGFVWRLRSGRLQPGYPALASRHWQGLPSPVDAAFEDAQGQIWFFQGAQYWVYDGEKPVLGPAPLSKLGLQGSPVHAALVWGPEKNKIYFFRGGDYWRFHPRTQRVDNPVPRRSTDWRGVPSEIDAAFQDAEGYAYFLRGHLYWKFDPVKVKVLEGFPRPVGPDFFDCAEPANTFR
Protein: Ribosomal protein S12 methylthiotransferase accessory factor YcaO (P75838)
Organism: Escherichia coli (strain K12)
Function: Involved in beta-methylthiolation of ribosomal protein S12.
Interaction partners:
- tRNA pseudouridine synthase D
- Ribosomal protein uS12 methylthiotransferase RimO
- Sulfur carrier protein ThiS adenylyltransferase
- Gamma-aminobutyraldehyde dehydrogenase
- Ribosomal protein uL16 3-hydroxylase
- 3-phenylpropionate/cinnamic acid dioxygenase subunit beta
- UPF0702 transmembrane protein YcaP
Sequence:
MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFWAK
Protein: HTH-type transcriptional regulator ZntR (Zn(II)-responsive regulator of zntA) (P0ACS5)
Organism: Escherichia coli (strain K12)
Function: Zinc-responsive transcriptional regulator of zntA.
Interaction partners:
- Uncharacterized protein YhdN
- Zinc/cadmium/lead-transporting P-type ATPase
- Arsenical resistance operon repressor
- Transcriptional repressor RcnR
- Zinc transporter ZitB
- Nickel-responsive regulator
- Lysine-specific permease LysP
- Transcriptional regulator MntR
- Cation-efflux pump FieF
- Zinc transporter ZupT
Sequence:
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC
Protein: Superoxide dismutase (EC 1.15.1.1) (Q57Z58)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Large ribosomal subunit protein uL15/eL18 domain-containing protein
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein uL3m
Sequence:
MRSVMMRCATGHHMAPLGLACMQYATLPNLKKPNGAAAELPPLQFNWKDGCAPVLSPRQLELHYTKHHKAYVDKLNALAGATYDGKTMEDIIVALANDSEKKVLFNQAAQHFNHSFYWLCITPNGKPMPKSLESALTAQFGSVDGFKDTFMQAGANNFGSGWTWLCVDPKNKGKPLVIDNTSNAGCPITKGLRPVFTVDVWEHAYYKDFENRRVDYLKEIWTIVDWEFVSRTYEQAMK
Protein: GRAM domain containing 1B (A0A1W2PQ30)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPAANMMENRPLPALQVPEPQGAPEGSPVWSSSSTPTLRRRRFKMRRMKNVQEQSLEAGLARDLPAVLAPGKEFLQLPSIEITPSSDEDTPWSNCSTPSASPRRKRFLLRKWLRVRERKECSESRVLSLNGFVFLCGATESLITFPGIPSPNLFNYIDFNSLKLADFHCTKLKI
Protein: Chromodomain helicase hrp3 (EC 3.6.4.-) (ATP-dependent helicase hrp3) (O14139)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor.
Subcellular location: Nucleus {ECO:0000269|PubMed:12127990}.
Interaction partners:
- FACT complex subunit pob3
- Histone H4
- FACT complex subunit spt16
- Transcription elongation factor spt5
- Histone H3.1/H3.2
- RNA polymerase-associated protein C651.09c
- Histone H3.3
- Transcription elongation factor spt4
- Putative ATP-dependent RNA helicase ste13
- Histone-lysine N-methyltransferase, H3 lysine-36 specific
Sequence:
MSTSAIALALSSSKAIEQLDHVQTETPNLKQEMSESPSNSGVASKRKLQSTEWLDPELYGLRRSGRTRSNPGRYVDTDDQEDVFPSKHRKGTRNGSSFSRHRTIRDLDDEAESVTSEESESDDSSYGGTPKKRSRQKKSNTYVQDEIRFSSRNSKGVNYNEDAYFESFEEEEEEEMYEYATEVSEEPEDTRAIDVVLDHRLIEGHDGSTPSEDYEFLIKWVNFSHLHCTWEPYNNISMIRGSKKVDNHIKQVILLDREIREDPTTTREDIEAMDIEKERKRENYEEYKQVDRIVAKHLNSDGSVEYLVKWKQLLYDFCTWEASSIIEPIAATEIQAFQEREESALSPSRGTNYGNSRPKYRKLEQQPSYITGGELRDFQLTGVNWMAYLWHKNENGILADEMGLGKTVQTVAFLSYLAHSLRQHGPFLVVVPLSTVPAWQETLALWASDMNCISYLGNTTSRQVIRDYEFYVDGTQKIKFNLLLTTYEYVLKDRSVLSNIKWQYMAIDEAHRLKNSESSLYEALSQFKNSNRLLITGTPLQNNIRELAALVDFLMPGKFEIREEINLEAPDEEQEAYIRSLQEHLQPYILRRLKKDVEKSLPSKSERILRVELSDLQMYWYKNILTRNYRVLTQSISSGSQISLLNIVVELKKASNHPYLFDGVEESWMQKINSQGRRDEVLKGLIMNSGKMVLLDKLLSRLRRDGHRVLIFSQMVRMLDILGDYLSLRGYPHQRLDGTVPAAVRRTSIDHFNAPNSPDFVFLLSTRAGGLGINLMTADTVIIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLLSKDTIEEDVLERARRKMILEYAIISLGVTDKQKNSKNDKFSAEELSAILKFGASNMFKAENNQKKLEDMNLDEILEHAEDHDTSNDVGGASMGGEEFLKQFEVTDYKADVSWDDIIPLTEREKFEEEDRLREEEEALKQEIELSSRRGNRPYPSSAVESPSYSGTSERKSKKQMLKDEVLLEKEIRLLYRAMIRYGSLEHRYNDIVKYADLTTQDAHVIKKIAADLVTASRKAVSAAEKDLSNDQSNNKSSRKALLITFKGVKNINAETLVQRLNDLDILYDAMPTSGYSNFQIPMHVRSVHGWSCQWGPREDSMLLSGICKHGFGAWLEIRDDPELKMKDKIFLEDTKQTDNSVPKDKENKEKKVPSAVHLVRRGEYLLSALREHHQNFGIKSSPAISTNGKTQPKKQTANRRQSGKPNVKSAQKIESATRTPSPAISESRKKPSSKDTKIETPSREQSRSQTASPVKSEKDDGNVSLNAEQKARCKELMYPVRKHMKRLRKDSSGLGRAELVKLLTECLTTIGKHIEKTVNDTPSEEKATVRKNLWMFACYFWPKEEVKYTSLISMYEKMK
Protein: Photosystem II reaction center protein M (PSII-M) (Q6ENI6)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00438}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00438}.
Interaction partners:
- Photosystem II CP47 reaction center protein
- Uncharacterized protein
- Photosystem II reaction center protein H
- Photosystem II CP43 reaction center protein
- Photosystem II reaction center protein I
- Photosystem II reaction center protein L
- Photosystem II reaction center protein Z
- Cytochrome b6-f complex subunit 4
- Cytochrome b559 subunit beta
- Photosystem II protein D1
Sequence:
MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
Protein: Amino acid transporter, putative (Q57UX8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLSPTEALGSGKAHTEVVTDEGEGYGAMSAADEKSHHKNGNTLTTDSKFMQCINAIIPHGGALSTTFNLGSATLGAGVISLAIAFQMSGVIPSILILITVTVLTIYSVGLMMQAVEMTGYNSYADLSRNLFGPGWDYFTISVSWLFTFGTCVSYVIATGYLVDSVLSGSSALEFFQGKTGNRVITSIIWFVGMFSLSLPKEINSLRYASAIAVLFVFYFVICIVVHSAKNGLKDGKLPEDVEMFKSGNRAIEGLSIFMFSYLCHMNCFSIYSEMRKPSARRMTLHTTYSMSMCCVVYIIAGFFGYTDVGNKSVETVFEIYDVKGDVMMAIAFAGMLLKICVGFSLCMQPARDCCYYIIGWDLNTLETWKNCLFCGCMALCALLLGLFIPDLNTVFGLLGSFCGGVLGFCIPALYRMYCGNWGISQVGVVNYVCTYLLLISGVIAVVFGTAASIYNVAV
Protein: Transcriptional regulator Dnr (G3XCW6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Two-component response regulator NarL
- Nitrite reductase
- Oxygen-independent coproporphyrinogen III oxidase
- Sensor protein
- Nitrous-oxide reductase
- Regulatory protein NosR
- Metallo-beta-lactamase domain-containing protein
- Denitrification regulatory protein NirQ
- Arginine deiminase
- Nitric oxide reductase subunit B
Sequence:
MEFQRVHQQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLTPEGQEKILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLRQLQDNTPLALALLAKLSTRLHQRIDEIETLSLKNATHRVVRYLLTLAAHAPGENCRVEIPVAKQLVAGHLSIQPETFSRIMHRLGDEGIIHLDGREISILDRERLECFE
Protein: Glutathione S-Transferase (Q93701)
Organism: Caenorhabditis elegans
Interaction partners:
- Methyltransferase domain-containing protein
Sequence:
MPSYKFTYFPFRGLGEPVRLLFHLADCPFKDERFSFEEWGAVKSKSPMGQLPILGVDGLEIPQSAAILRYLALKFGFAGKTPEDRAWVDAVVDRFKDFFVEFKKFLVAKRGGKSEEEVAKVVSESVVPAMESYFKLLNGLLERSKSGFLIGNSITYADLVVVNNLETLRNFGFLNASEQPKLTALLEKVYSQPGIKEYVSSRTASDF
Protein: NACHT, LRR and PYD domains-containing protein 9B (NALP-delta) (Q66X22)
Organism: Mus musculus (Mouse)
Function: As the sensor component of the NLRP9 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens, including rotavirus, initiates the formation of the inflammasome polymeric complex, made of NLRP9, PYCARD and CASP1. Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and release in the extracellular milieu. The active cytokines stimulate inflammatory responses. Inflammasomes can also induce pyroptosis, an inflammatory form of programmed cell death. NLRP9 inflammasome activation may be initiated by DHX9 interaction with viral double-stranded RNA (dsRNA), preferentially to short dsRNA segments.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:26411641}. Inflammasome {ECO:0000250|UniProtKB:Q7RTR0}.
Interaction partners:
- NLR family CARD domain-containing protein 4
- NACHT, LRR and PYD domains-containing protein 6
- Caspase-1
- NACHT, LRR and PYD domains-containing protein 3
- NACHT, LRR and PYD domains-containing protein 1a
- Pyrin
- Interferon-inducible protein AIM2
- Caspase-4
- Apoptosis-associated speck-like protein containing a CARD
- Gasdermin-D
Sequence:
MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN
Protein: Complement C1q subcomponent subunit A precursor (Zgc:109903) (Q504F7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MQPSAFFAFLWAGALLPFSFCQDECVKHGRNGADGPNGRDGLPGPKGEKGEPALQVKLSSIALEELKGDMGVRGPPGEPGLEGLMGAIGPRGPLGPAGPRGSSVGADGAKASEKPAFSVLRNEASQAQYKQPVTFNDKLSDANDDFQIKTGYFTCKVPGVYYFVFHASSEGRLCLRLKSTSAPPVSLSFCDFNSKSVSLVVSGGAVLTLLKGDKVWIEPFAGDGGVGQMPKRLYAVFNGFLIYRNAE