wanglab/gogpt-training-data huggingface dataset:
Protein: Glycine-glutamate dipeptide porin OpdP (Q9HVS0)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable binding protein component of ABC transporter
- ABC-type dipeptide transporter
- Probable permease of ABC transporter
- Dipeptide-binding protein
- ABC-type dipeptide transporter
- FUSC family protein
- Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein
Sequence:
MMRNQRVTSATLGLALLAASAPGWAADEQENPPAPDNPSYAAEVQSIPSVAKPIKGQAGATGLVEGQSLTLTTRNFYSRENMKDSFTFRIPKAGGGSQRIHQRNAWVQGTVLKYSSGYTQGTVGFGFDVAAFNEIALERGKGRIGGGGNRTLANSDGEALGEWSKLGVANIRLRASNTEFKAGRFLVNTPVFSYIDNRALPSSFTGFAVTSEELDNLSLQAGSFRKVSPRTGSGDEDMTTEYGTRQVKGDRLNYLGGNYKPLDGLEISLYGSHFQDVWNQYYLGVTHDIGDLENGIALRTAFNGYHTGDTGAREAGYIDNDTWSLAFTLGHRAHALTLAYQQVDGNEYFDYVHETSAIFLANSMLADYNSPNEKSAQIRYETDWSYYGVPGLSTGVWYVKGWDIDGTHYDGDRNGAYGNYAEVRAQDGEKHHELGLMAAYKVQNGPIKDSTFKLTYMMHKASQNQIDGSVNELRLVSTFPFNLL
Protein: Endonuclease 8-like 3 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase FPG2) (DNA glycosylase/AP lyase Neil3) (Endonuclease VIII-like 3) (Nei-like protein 3) (Q8K203)
Organism: Mus musculus (Mouse)
Function: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). Mediates interstrand cross-link repair in response to replication stress: acts by mediating DNA glycosylase activity, cleaving one of the two N-glycosyl bonds comprising the interstrand cross-link, which avoids the formation of a double-strand break but generates an abasic site that is bypassed by translesion synthesis polymerases (By similarity). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues.
Subcellular location: Nucleus {ECO:0000269|PubMed:16428305}. Chromosome {ECO:0000250|UniProtKB:A0A1L8HU22}. Note=Recruited to replication stress sites via interaction with ubiquitinated CMG helicase. {ECO:0000250|UniProtKB:A0A1L8HU22}.
Interaction partners:
- Endonuclease III-like protein 1 lyase)
- Endonuclease 8-like 1 lyase Neil1)
- N-glycosylase/DNA lyase
- Adenine DNA glycosylase
- Exonuclease 1
- Flap endonuclease 1
- Dephospho-CoA kinase domain-containing protein
- Bifunctional coenzyme A synthase
- Uracil-DNA glycosylase
- DNA polymerase theta
Sequence:
MVEGPGCTLNGEKIRARVLPGQAVTGVRGTALQSLLGPAMSPAASLADVATSAAPMNAKDSGWKLLRLFNGYVYSGVETLGKELFMYFGPRALRIHFGMKGSILINPREGENRAGASPALAVQLTRDLICFYDSSVELRNSVESQQRVRVMEELDICSPKFSFSRAESEVKKQGDRMLCDVLLDQRVLPGVGNIIKNEALFDSGLHPAVKVCQLSDKQACHLVKMTRDFSILFYRCCKAGSAISKHCKVYKRPNCDQCHSKITVCRFGENSRMTYFCPHCQKENPQCVQVCQLPTRNTEISWTPRGEDCFTDSVARKSEEQWSCVVCTLINRPSAKACDACLTTRPLDSVLKNRENSIAFNNLVKYPCNNFENTHTEVKINRKTAFGNTTLVLTDLSNKSSALARKKRANHTIDGESQMFLPTDIGFSDSQHPSKEGINYITQPSNKVNISPTVCAQSKLFSSAHKKFKPAHTSATELKSYNSGLSNSELQTNRTRGHHSKSDGSPLCKMHHRRCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWADLSFPFCRHGKRSIMKTVLKIGPNNGKNFFVCPLEKKKQCNFFQWAENGPGMEIVPGC
Protein: RAS protein activator like 2 (D3Z7S1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLSEKLDSYLSVSEVEMGSSCDKEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNADDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFE
Protein: Ig-like domain-containing protein (Q95Q97)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Tubulin beta chain
- Protein dyf-7
- Innexin unc-7
- Innexin unc-9
Sequence:
MWHYRLTTILLIISIIHSIRAKRKLKEQEIIQRILKDYDWRVRPRGMNATWPDTGGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAYERYEESGDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLRQSLPSFELQDVVTDYCTSLTNTGEYSCARVVLRLRREYSYYLIQLYIPCIMLVVVSWVSFWLDKDAVPARVSLGVTTLLTMTTQASGINSKLPPVSYIKAVDVWIGVCLAFIFGALLEYAVVNYYGRKEFLRKEKKKKTRIDDCVCPSDRPPLRLDLSAYRSVKRLPIIKRISEILSTNIDISRRVDLMSRLTFPLTFFSFLIFYYVAYVKQSRD
Protein: Oogenesis-related (Oogenesis-related protein) (A4UU77)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Granulin a
- Cystathionine beta-synthase
- Elongation factor 1-alpha
- Actin alpha 1, skeletal muscle b.
- Transcription factor Jun
- Acetyl-coenzyme A synthetase.
- Glyceraldehyde-3-phosphate dehydrogenase
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Catenin beta-1
- Cytochrome b
Sequence:
MTDQCNYAVESENAEGQEKKAVAKRRGAVSAVFCRISQFWPVSLTMRALRGLWSLFGFSTPVKSVSLASEEKSSSPNERQCRAVRKRLHRVTRILLSILPRRIQSALGYPVCTSIGCAVSPEVRCSPTKPCGKGSKRKQDDLDEDEEVEQQSWVEALTQELAEEDHVADPDYEPSAVETDSEEYRSHNDTESDLEVEKGVVVIKDLETVVPSEAQ
Protein: TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II) (Q62312)
Organism: Mus musculus (Mouse)
Function: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P37173}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P37173}. Membrane raft {ECO:0000250|UniProtKB:P37173}.
Interaction partners:
- Transforming growth factor beta-2 proprotein
- Transforming growth factor beta-3 proprotein
- TGF-beta receptor type-1
- Transforming growth factor beta-1 proprotein
- Mothers against decapentaplegic homolog 3
- Mothers against decapentaplegic homolog 2
- Mothers against decapentaplegic homolog 4
- Mothers against decapentaplegic homolog 7
- Activin receptor type-1-like
- Endoglin
Sequence:
MGRGLLRGLWPLHIVLWTRIASTIPPHVPKSVNSDVMASDNGGAVKLPQLCKFCDVRLSTCDNQKSCMSNCSITAICEKPHEVCVAVWRKNDKNITLETVCHDPKLTYHGFTLEDAASPKCVMKEKKRAGETFFMCACNMEECNDYIIFSEEYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLSPSWESSKPRKLMDFSDNCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYSSWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWDHDPEARLTAQCVAERFSELEHPERLSGRSCSQEKIPEDGSLNTTK
Protein: ABI gene family member 3 (New molecule including SH3) (Nesh) (Q8BYZ1)
Organism: Mus musculus (Mouse)
Function: Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Cytoplasmic FMR1-interacting protein 1
- Nck-associated protein 1
- Nck-associated protein 1-like
- Actin-binding protein WASF2
- Actin-binding protein WASF1
- Cytoplasmic FMR1-interacting protein 2
- Actin-binding protein WASF3
- Protein BRICK1
- Guanine nucleotide-binding protein G
- Abl interactor 2
Sequence:
MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHMEKVARREIGTLATVVRLPSNQKVIPPESLPSLTPYHRKPLNFACLDDIGHGVKDLSTQLSRTGTLSRKSIKAPATPVSATLGRPPRIPEPVQLPAVPDGKLSAASSASSLASAGSAEGASGIPQSKGQVAPATPPPPPVAPVTPPPPPLSAEVFLPPPPLEVSQPPLEAELPLPPPPALEGDELGLLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC
Protein: Protein asteroid (Q9VPW1)
Organism: Drosophila melanogaster (Fruit fly)
Function: May function in EGF receptor signaling. May play a role in compound eye morphogenesis.
Interaction partners:
- MIP30042p
- Kelch-like protein diablo
Sequence:
MGVRGLTSYIAQRAEIYLKPHELHSTALVIDGDNLSCNLYKDVTGSYSAFGGDYDDFYRAVVQFFQVLAECNIRPYVLMDGGYEERKLRTVSTRLRNKISVIKKINPNASITLFPLHLKEVFVDAVRDCGVPVMRCVFEADDELAALARKLNCPVLSYDSDFYIHNVKYIPLITLTVKVLTKQVKDKNSSNQKDSRDLRHCEAKNVKKRTRANKIVTGIQTTGLTASTKGSSKTYKYLDCCIYRVSHLCGRGTLSPEKLPLFAALLGNDYIARSAFKNFFAAGMGKAGRSRKLKLQQKRIQVILTWLKEETAESALAKVLSRLKKNQRDSLVSQVNAAISGYSNELCHAYDYFDEHYENAFPYIEPVSEEECSDDEHSSSSDEKFSDVEEGEDQEEADNQDEEQQEENQDVDSGDEEEEEADEGLELEVEDKTLLFPQWFLDKLYPAHLPRSFVDLMHLRKYINNPQIEHFPFHDSNEVALPILNYVFALLHHVECEKIELPLEVDMDIEGSTVPYLTYLTRALRVTNVRYFKMPIEKKPAYPFDPLSPDARHLRAVFEDNAPNADTEKLFSKLDQLPEDLRLYFLAIIYWLHRSEHCDLLHLHSLILSLVVLRTIDVTIPAEREVKTFLKRFGKTLKAERAVRDKEAAEGIKRGIKPALLELSVPDRMAHVPKSDCYLTQERLLPHFHMQEIFKKKFDLYSTTVIHAFAEFQAVVYQLNGLNSLLDFPLLSPRMNQLYCGAFLYNMYDVLRNRADVRYHVENFLLPDSKLMFDFYCYLYDWCAEFIPTWKRLEVDPTAAKALQKKRLKKQRQAARKVELREAIADPNAEMVEDADPENDFFDLNNKFCALKVA
Protein: Quaking related 58E-1, isoform D (A0A0B4LG88)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPRDYDRDYNEDAADYKRKRRDEEPAATGAPETPEADGGGHTTSHAALRDTPQLNEKTNAYLQECLLEKKTLEKKHIITKRLLDDEVEKILVSGRIPKPEIYANVYSEKPIRVAQKVLFPIKEYPKFNFVGKILGPKGNTLRQLQEETMCKMVVMGRNSMRDHGKEEELRSSGNPKYAHLSRDLHVEISTVAPPAEAYHRISYALGEIRKFMIPDANDDIRLEQLREMDGKERMYKKSHHYSKSYGDHGAYSSRTPPPASSKPKVYSILEKARYVMDDPNYGIVKTHRSRDHELYDHHGEYDRYATPPPQTSKHSTHHAQYDSSSYERDYRPKPSNGRSSSSYRPTTSGSGSHSSAHYETGSRSRESVRYRSAPYPKIR
Protein: Meiotic coiled-coil protein 5 (Meiotically up-regulated gene 21 protein) (Nuclear migration protein num1) (Q9Y7J9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in chromosome segregation. Facilitates nuclear oscillation during meiotic prophase I, the 'horsetail' phase, by acting as a dynein anchor. Essential for anchoring dhc1 to the cortex. Required for proper sliding of the microtubules along the cell cortex, which leads to the proper U-turn movement of the nucleus.
Subcellular location: Cytoplasm, cell cortex {ECO:0000269|PubMed:16585273, ECO:0000269|PubMed:16624923, ECO:0000269|PubMed:16823372}. Note=Localizes to the cell cortex during the 'horsetail' phase of mitosis.
Interaction partners:
- Dynamin-related protein dnm1
- Dynein intermediate chain 1
- Dynein heavy chain, cytoplasmic
- Meiotically up-regulated gene 1 protein
- NURS complex subunit red1
- Meiotically up-regulated gene 43 protein
- Meiotic coiled-coil protein 6
- Microtubule-associated protein mmb1
- Pre-mRNA-splicing factor cwf7
- Meiosis-specific transcription factor mei4
Sequence:
MEKKQDNEVELYSIDLKNRNESAKIKLAYAKALEESILCETRKIEQEIKDQVVQKENKTYFNNKFDNRYKLRDLEKNLAEEEVRITEMLTIQRQDIAIERRKNTNCFSESSQVDQYSVTETNLQYATNIGLNLLQQLRYLRLQLSEKEDLHKKLSVDNAHLIKQLDLLSSNMKTLMKEKTKVQGQRDLLEQRLQGLMKKLTEVESLTVSLNDEKNKLTLELTNLRICLHELQLNAEKGETIDESEDSKNTLVTEDENDDSVFLESSSDKYFDSSSFDAEQEEKHDFPIDPFLSLESNVQTSVSQSSAVLKSINLAKQELVSVNHLVADDTKTPSPNLSSEIIENTKADIKKSIRSLNKAVSPENSIDIEDETDRDDEFICFLLSYQQLQKALKSNLGLFQLSCLYPLSLNHLIQSFFQSLTSQISIKDIDSKNKQVIKLFKPTKSSDRQEIFELAQFEPRQKFPIDTNSSKCDMSASTEMHLKDTEKFANFKLKENILNHSSIYERDVSYLPALNKGGRENYLNNRVSSYRLVKPILNSYGNHVLNRIQHDILENHFCCLKNVKDFVCGANTISMQWNLQKNMEFISSVFSLIKNEVNDTSANSVILRTDALSNVATTRLKRKLTSAIIDCSIPRRRLRHYSNPEIAEFKNFRLSTDISHSNVRNSKKLCSNGSMNCMRQGKAVFPRKIPYQEHDWEQWEKIAQSSMFKNRSIASRQSLETSDVTLDINMSSRHSNGTSSMLFKDFTKHNNWEASTYPSAPKNTRTYPTAEVEKTRHDSSQSARQLKARSTATTISISLSTVSDVFTLPRNNLKSKTNTKKCRDNLNLSGLSSSTCNANSVNKLMKHVMMGNEMMKYPRSESFKMFKKSHWRYFWINPHCEMLCWSKTNPFIEKGRKNQVKSVKIKGMTIIKAPDALKNANLHNEVIVMQTTDKPIVLKAKSKKIHNIWVQAIKQINHKAIFDTKPGI
Protein: Sugar transporter ERD6-like 8 (Q0WQ63)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sugar transporter.
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Vacuolar ATPase assembly integral membrane protein VMA21 homolog
- At1g20770
Sequence:
METRKDDMEKRNDKSEPLLLPENGSDVSEEASWMVYLSTIIAVCGSYEFGTCVGYSAPTQFGIMEELNLSYSQFSVFGSILNMGAVLGAITSGKISDFIGRKGAMRLSSVISAIGWLIIYLAKGDVPLDFGRFLTGYGCGTLSFVVPVFIAEISPRKLRGALATLNQLFIVIGLASMFLIGAVVNWRTLALTGVAPCVVLFFGTWFIPESPRWLEMVGRHSDFEIALQKLRGPQANITREAGEIQEYLASLAHLPKATLMDLIDKKNIRFVIVGVGLMFFQQFVGINGVIFYAQQIFVSAGASPTLGSILYSIEQVVLTALGATLLIDRLGRRPLLMASAVGMLIGCLLIGNSFLLKAHGLALDIIPALAVSGVLVYIGSFSIGMGAIPWVIMSEIFPINLKGTAGGLVTVVNWLSSWLVSFTFNFLMIWSPHGTFYVYGGVCVLAIIFIAKLVPETKGRTLEEIQAMMM
Protein: Nuclear receptor coactivator 7 (Q6DFV7)
Organism: Mus musculus (Mouse)
Function: Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIVSAASSKSRSGKDDANSDILEQDKFNVTAEGDHSTDDKKKRKSNQLKEIRRTELKRYYSVDDNQNKTHDKKEKKMMVQKPQGTMEYTAGSQDTLNSVALKFNVTPNKLVELNKLFTHTIVPGQVLFVPDANISSSTIQLSSSTPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYSDISHMKIKDALPSDLPRDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLALDAKSVRSPEESTERTCTRIEPPDNSELWKLKNLQSSRGTTSESPSVTQLSMRAALEPTAKENCLLKGDEDFVDLEELSSQPESGINKGDATKECLSYDQKKDGPHTVMSAKKGHVQSAQEVMGPESDTELKGALDLETAEKQDEAPEVDKHSGSPENLGESTLNIHEDLDKIKLIEFYLNKNKEGSQLLENVQKSELSDRKSIEPGGIDITLSSSLPQAGDSPPEDNKEPGTLWVKGGETLPLKLDPSAEETVINNKEVLDSLGSSLDKMCHSAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTATMVQQYSKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEEEEEEEEGLPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE
Protein: Peripherin (Prph protein) (Q502Q7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Dihydropyrimidinase-like 5a.
Sequence:
MSHYSYRTSHHRSYGTPSVSSRIGGRYTSSIPSRPVDFRSRSSAPAPRLSYDKVDFSLAEAVNQEFLATRSNEKRELQELNDRFASFIEKVRYLEQQNSRLTQELGQFKEQQQGPSGRLGDLCQQEMRELRRQLELMGKDRDQMQVERDNLAEDVALLKQRLNEEMQKREEAENNLTLFRKDVDDATLARLELERKIESLMDEIEFLKKMHDEEIQDVQVSVQSQQMKMEVMETSSRPDLTAALRDIRSQYESIASKNMQESEEWYKSKFADLTDSAKRNAEAMRQSKQDNNDLRRQIQAQNCDIEALKSTNEALLRQMREMEEQFTLEAGNYQDAVGRLEEEIRHLKEEMSRHLREYQDLLNVKMALDIEIATYRKLLEGEESRIAVPIMKMPSMSGHSGDYGQFSDPAPGKKVVIKTVEIRDGEVVKESTKEKARDEKKD
Protein: FHF complex subunit HOOK-interacting protein 1A (FHIP1A) (FTS- and Hook-interacting protein like) (FHIP-L) (Q05DH4)
Organism: Homo sapiens (Human)
Function: Probable component of the FTS/Hook/FHIP complex (FHF complex). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
Interaction partners:
- AKT-interacting protein
- Protein Hook homolog 3
Sequence:
MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLKMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFPEAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPEMFLQSLTEEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYDDLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC
Protein: Guanine nucleotide-binding protein subunit alpha (W5UI00)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Interaction partners:
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- 5-hydroxytryptamine receptor 2B
- Type II GnRH receptor
- Gonadotropin-releasing hormone II receptor-like isoform X1.
- 5-hydroxytryptamine receptor 2A
Sequence:
MTLDSVMACCLSEEAKEARRINDEIERQLRRDKKDSRRELKLLLLGTGESGKSTFIKQMRIIHGSGYSEEDKKGFTKLVYQNIFTSVQSMIRAMDTLQIPYKYEHNKGNANIVREVDVEKVSVFINPYVDAIKSLWKDPGIQECYDRRREYQLSDSTKYYLNSLDRIADSSFVPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMFSHLVDYFPEYDGPQRDAQAGREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
Protein: Bowman-Birk type proteinase inhibitor A4 (HOSPI-A4) (C0HLS6)
Organism: Hyacinthus orientalis (Common hyacinth)
Function: Serine protease inhibitor. Inhibits trypsin (Ki=12nM) and weakly inhibits chymotrypsin with (Ki=460nm). Does not inhibit bacterial subtilisin.
Interaction partners:
Sequence:
WPPVEGRPSCKRCGACTRMWPPEANRCVCDDIVPQCHEGCSKCEKVDTRSGKPLYQCQSFEYYNCAA
Protein: Protein GnsA (P0AC92)
Organism: Escherichia coli (strain K12)
Function: Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.
Interaction partners:
- Uncharacterized protein YmcE
Sequence:
MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKMTGLESYDVKIKIM
Protein: Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein) (Q96D96)
Organism: Homo sapiens (Human)
Function: Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20144758, ECO:0000269|PubMed:22020278}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000305|PubMed:20548053}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, phagosome membrane {ECO:0000269|PubMed:24415791}; Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:20144758}; Multi-pass membrane protein {ECO:0000255}. Note=Detected within the principal piece of the sperm flagellum (PubMed:20144758). Detected mainly at intracellular membranes upon overexpression in HeLa cells (PubMed:20147290). {ECO:0000269|PubMed:20144758, ECO:0000269|PubMed:20147290}.
Interaction partners:
Sequence:
MATWDEKAVTRRAKVAPAERMSKFLRHFTVVGDDYHAWNINYKKWENEEEEEEEEQPPPTPVSGEEGRAAAPDVAPAPGPAPRAPLDFRGMLRKLFSSHRFQVIIICLVVLDALLVLAELILDLKIIQPDKNNYAAMVFHYMSITILVFFMMEIIFKLFVFRLEFFHHKFEILDAVVVVVSFILDIVLLFQEHQFEALGLLILLRLWRVARIINGIIISVKTRSERQLLRLKQMNVQLAAKIQHLEFSCSEKEQEIERLNKLLRQHGLLGEVN
Protein: Cell wall protein IFF11 (Adhesin-like protein IFF11) (Q5A7R7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:17371861}.
Interaction partners:
- Uncharacterized protein
Sequence:
MLLSNLVIPLLATSATVSATFDVTSSLTKYAAFDFGVGDISIQKSASFSLINTFDCAFQGDINIEKDCEFLIASTAKALKLTFNNIFHKIENKGKWIVHTLESAAASTCNIIVKSFVNTGEIILAFKGHVLAPIINIAASHWVNHGCLHLFQEIKSISVAILGVVGGTIENHGTICLTNQLCKQVTKIIGSGCIALEKSSSFFISNSFLSIDAQHTFYLGEGNPTIQAQAVSLPQTFKVANFGANGSHKIGLNLPLLSITIAGKKGWSYDTKTGILTLTANGFISQKFDIGLGYDPSKFEVCTDNSVGIVSVIKGSIKYNGPCPHAGRPSVCQICPGVPTPPVITSSATAITSTQSKTTSSSSTSSIATTSTTSSKPKPTTVSTSSIASTTTPDGSYSTSFVTVTAETTKVVTITSCSNNACHPTTAPTGLTVVTLTTSDVKTVVTTYCPLTQTVTLGVTGTKTVDLGCPTGYFGYNGYIGKGVSIGHGGAAASASAGFQIGFDIFKNHHF
Protein: Bone morphogenetic protein 5 (D4A7P9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Bone morphogenetic protein receptor type-2
- Bone morphogenetic protein receptor type-1A
- Activin receptor type-2B
- Activin receptor type-2A
- Noggin
- Activin receptor type-1
- Chordin
- Serine/threonine-protein kinase receptor
- Neuroblastoma suppressor of tumorigenicity 1
- Hemojuvelin
Sequence:
MHWTVFLLRGIVGFLWSSWVQVGYAKGGLGDNHVHSSFIYRRLRNHERREIQREILSILGLPHRPRPFSPGKQASSAPLFMLDLYNAMASEENPEESEYLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRIPLTTQSPPLASLHDTNFLNDADMVMSFVNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDKSNHRFENETIKISIYQIIKEYTNRDADLFLLDTRKAQALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGDGRSINVKSAGLVGRHGPQSKQPFMVAFFKASEVLLRSVRAASKRKNQNRNKSSSHQDPSRIPSAGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGCH
Protein: Phospholipid-transporting ATPase, putative (Q382N5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MADNSNVGVENTDHARSFVEVNILRGDLNAARRFPSNYVRTSKYTLATCIPKSLLNQFRCVSNIYFLFVTIITMIPVVSPVNPLSTLLPLCIVVGVGMWKDLWEDGKRRKSDKLVNSVGVQVLRGSDFVSVPSRDVRAGDVILCGLGDVVPADAVVLNTSLVDGVTYIETSNLDGETNAKTRRAKPETIKALGTVEDIIEGCLPDAATCAHFLNNGSLVGWKRCDSRGGDNGKGAISQNVLTENGRTSGGTSGQRARASSAFRDVEVTEVEDGTPQSVELPPPTNVTQSFAEQTSKKGTEGGHGRTSTATPTPLETRGSVCNTLELSSKERTITECDDRVPSSTVETSDIRDRVRGGPSGLCSSSNPFAAGTASNIYPRAGAPGSAVALANDGNGVLNDARGDGDFKGVLLRGATPCPDLHSWIGQLRLRCGSVVSLSIDQFLPRGCIIRNTEWVLCAVVYTGKNTKMLLNLKSKGEKSSLTSRRINLINIILLFVHQTALITLCTMSVHWRAERLNGLEGAGSGHTTWYIQWALSRYGASKYFALMYLTNFILLSFLIPISLYVTMELNKVLQLYLIANDRRMASYDEFKGVLRYSRPKTSCLNSQLAYVRYVFTDKTGTLTENVMTYVGGCTATERHDEKERPGALGEAFLRLVEARRLSVPPAVGEPIMTTDALERRQVPQQGRFDFDEEAMEKEPLFRYLRNLSLCHSVVCFDRPEVESAVAAAVEAAAASGHSVLGGSLPPGSQHAFTRRPSAADATLPNNNRIMGCSGTTDAVEMVCHRRVSSITPGSGSVFGASPSTGVGRFLHGHTGSASWRMTCHNDALMHERSLTMSRKVREFRDESKIYEGQSLDEVALVCAARDNLFALQGRTSKHVFVKVVQKVMCYEVVAELQFTSQRKLMSVLLSRCPDMDNASTGTQDNVRISYHRKVQETQTSPSFARAWETPTRSSGQHKTMKVLGDQKGDPTHPVTVEEDRKDRPVDSNARGKKLPFLLLVKGADSSMMSIMNKQNPRNIDLKDLFEVEIDSVAKKGLRTLVLGQRWVSEEEARDWLVKFNEAQCRLNDRDEALHEVYALLEKDVDLIGTTAVSDELQEDVPETVKFLMQADIVVWMLTGDKRETAVTIACTSGIIESGCEDMVHHLDVCSQLSGTTDLQTELKSERIREVLRSQLSAASNKCDSAEEQYGKDTHKMVLVVDGLTLDAIFCDADLTSEFFSIGMRCRSAVCCRMTPLQKAKIVKLFQENTGGVALAIGDGANDVSMIQESSVGIGIMGLEGSQAELASDYAIPKFRFLKRLLMVHGRFSLYRDAHCLVYSLHKNAFLTSAIVVYTISSGFSGMVLIDSWLITFFNLVYCSLQPVLMGVYDKDVEDELAESLPSLYPPLSRENMFFRWGYFTKWFVDGVLLGVLLFVLTYYVLGDDDALHPYRSGSVEDYGTLYFILLLFLVNLRAASAIVCYNLITVAVLALCFIAIPFLTLFYSALPNVFGSNRCVYVAIELVGNIKLWLMLLLCFGIYIMYIMGSNAYIELFKPWLNGERAMRAAWESPYKGEHLAKVKLLRERSRTR
Protein: Zinc finger CCCH domain-containing protein 36 (AtC3H36) (Q9C7C3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Zinc finger CCCH domain-containing protein 39
- Zinc finger CCCH domain-containing protein 59
- Zinc finger CCCH domain-containing protein 17
- Zinc finger CCCH domain-containing protein 15
- Zinc finger CCCH domain-containing protein 2
- PPPDE putative thiol peptidase family protein
- Zinc finger CCCH domain-containing protein 14
- Zinc finger CCCH domain-containing protein 37
- Zinc finger CCCH domain-containing protein 54
- Zinc finger CCCH domain-containing protein 3
Sequence:
MDTRKRGRPEAGSFNSNGGGYKKSKQEMESYSTGLGSKSKPCTKFFSTSGCPFGENCHFLHYVPGGYNAVSQMTNMGPPIPQVSRNMQGSGNGGRFSGRGESGPGHVSNFGDSATARFSVDASLAGAIIGKGGVSSKQICRQTGVKLSIQDHERDPNLKNIVLEGTLEQISEASAMVKDLIGRLNSAAKKPPGGGLGGGGGMGSEGKPHPGSNFKTKICERFSKGNCTFGDRCHFAHGEAELRKSGIV