wanglab/gogpt-training-data huggingface dataset:
Protein: Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3) (A6XMH6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU364110}. Nucleus {ECO:0000256|RuleBase:RU364110}.
Interaction partners:
Sequence:
MLHRRFSVQKASLSADMVDTQTFGWPVGFGLSALELEELEDDTHSLDIKPFSTLDYSSISGIDYENNPTQNDPTPHMMDLTHMYSYRTQENYRTHEPIYRPEHSSYSPEENTYRAQQIQNSIKLEPESPPQFAENSVSFSKTPEDPSSSSLNIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLVYDHCDLHCRIHKKSRNKCQYCRFQKCLMVGMSHNAIRFGRMPQAEKEKLLAEFSSDVNHMHPESADLRALARHLYESYLKYFPLTKAKARAILSGKTSDNAPFVIHDMKSLVEGEQMINCRYMPLHEHRRSDLGIMHEVELRFFHSYQSRSAEAISEVTEFAKSIPGFINLDLNDQVTLLKYGVIEVMIIMISPLMNKDGTLISYGQIFMTREFLKSLRKPFCEMMEPKFEFSIKFNMLELDDCDMALFLAVIILSGDRPGLLDVKPIEDLQETVLHSLELQLKINHPDSLQLFAKVLQKMTDLRQLVTDHVQLIQMMKETEADWSLHPLLQEIMRDLY
Protein: Mitochondrial inner membrane protease subunit (EC 3.4.21.-) (E9PNR7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273, ECO:0000256|RuleBase:RU362041}.
Interaction partners:
Sequence:
MLRGVLGKTFRLVGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQNSDIVFAENLSRHFYGIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILTT
Protein: Guanylyl cyclase-activating protein 1 (Guanylate cyclase activator 1A) (Q5MAC8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MGDSSSMSATELSACKCHQWYRKFMTECPSGQLTFYEFKKFFGLKNLSEKSNAYVNTMFKTFDIDDDGCIDFMEYVAALSLVLKGGVQQKLRWYFKLFDMDGSGCIDKDELLLIFKAVQAINGAEPEISAEDLADIVFNKIDVNGDGELSLEEFMEGISADEKISEMLTQSLDLTRIVSNIYNDSYIEQEAEIIEDQA
Protein: Calmodulin-1 (CaM-1) (P13868)
Organism: Solanum tuberosum (Potato)
Function: Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
Interaction partners:
Sequence:
MAEQLTEEQIAEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMISEADADQNGTIDFPEFLNLMARKMKDTDSEEELKEAFKVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVRMMLAK
Protein: adenylate cyclase (EC 4.6.1.1) (Q2PDU2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSFPRTNSRKSPLKRKRLRPCHLDYANERLWEHSYLREKCKELNLEEEYRYYQVRLMVSNLTIFYVLFIILAMSFLTIELLYVQHYNAVFFNFVIRVVSTILVLTVLSINFCEKFVSRHRWVMIASSVLSVYLVVLTDIVMISYHFYKNDWPLNTSFDVFTLCMIYMFLPIPSIKGAALLASSVSLIYVAFFMHSLTFNAVYTDRDSFGYDVISTDILHNLGFNMMGIFFRIMNDTMVRASFLDRHQFIMEETWLRHALLQESILLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRTTESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCYYCVAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIWGTLG
Protein: Peroxisomal succinyl-coenzyme A thioesterase (EC 3.1.2.3) (Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib) (Q8BWN8)
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. In contrast to its human ortholog, functions essentially as a succinyl-CoA thioesterase with no activity with medium to long chain saturated acyl-CoAs and with a low activity toward glutaryl-CoA.
Subcellular location: Peroxisome {ECO:0000269|PubMed:16141203}.
Interaction partners:
- Acyl-coenzyme A thioesterase 3
- Cytosolic acyl coenzyme A thioester hydrolase
- Acyl-coenzyme A thioesterase THEM4
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Acyl-coenzyme A thioesterase THEM5
- Acyl-coenzyme A thioesterase 1
- Fructose-1,6-bisphosphatase 1
- Acyl-coenzyme A thioesterase 5
- ATP-dependent 6-phosphofructokinase, liver type
- Fructose-1,6-bisphosphatase isozyme 2
Sequence:
MAATLSVEPTGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARVPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFLVELEVLDGHEPDGGRRLARTVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGIIDVYGVGGGLLEYRAGLVAGHGFATLALAFYDFEDLPKELNVIEVDYFEEAVRYMLRHPKVKGPDIGLLGLSLGADVCLIMASFLNNVSATVSINGSAFSGNRHIKYKQTMIPPLGHDLRRMKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELYTQIASDRLQAHGKERPQVLSYPGTGHYIEPPYFPMCPASLHKIVNEAVIWGGEVKAHSKAQIDAWKQILFFFGKHLGSTHSRASCRL
Protein: P-loop NTPase domain-containing protein LPA1 homolog 1 (Protein LOW PHYTIC ACID 1 homolog 1) (Q9FJH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the accumulation of phytic acid in seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.
Interaction partners:
- Germin-like protein subfamily T member 3
- Protein DETOXIFICATION 32
- Inositol 3-kinase
- Inositol-tetrakisphosphate 1-kinase 1
- Inositol polyphosphate multikinase beta
- Inositol 1,3,4-trisphosphate 5/6-kinase 4
- Protein CRABS CLAW
- Inositol-pentakisphosphate 2-kinase
Sequence:
MTETTKVMYIVVVDGTDTAETVEEDGTGTWKDSFRYTRPVLQSTLQLMGCKARHAFKISRRVFELIRSEGSLILSPSLSPSHSKESEFQKTGDASACANVEKANKVNSLATDDVDKSKSKPFEVYKRRTTVVVSREIFVNVVCDALAEYKYVGHDQRADLILSCRIRERKESVTVLLCGTSGCGKSTLSALLGSRLGITTVVSTDSIRHMMRSFVDEKQNPLLWASTYHAGEYLDPVAVAESKARRRRAKKMDSIEDEKAKASEGGKAKNTQQTDVGSTKNTPVLLSPKQMAVEGFKAQSEMVIDNLDRLITAWEERKESVIVEGVHLSLNFVMGLMKKHPSIVPFMVYIANEEKHLERFAVRAKYMTLDPEKNKYVKYIRNIRTIQDYLCKRADKHLVPKINNTNVDKSVAAIHATVFSCLRRREAGEHLYDATTNTVSVIDDEYRNQCTANSLSSKGMFQLIQRKGSSRHLMALLNTDGTFARTWPVTGKVDESGKPVFCNEMIEENGMEHPVYGYLQKAEPVNLQFGLFGISAWPSDGATSRAGSVDDCKADMAETSSRYYSSCCSSPRMSEGTSKELKEDQSVHGSDEEVEDDPPEPDTDFSDDDNKRDHDEVGSVDEQSTKSDEEYDDLAMEDKSYWTDEEEESRDTIAIMSEKNNKQATKEDKYIQNLDLFLRTANQQLVEPLQLCASLLTCENGNTRLWLGKEKMRKRSLSISAIGKHGSGLGDAILLGAP
Protein: Atypical chemokine receptor 2 (C-C chemokine receptor D6) (Chemokine receptor CCR-10) (Chemokine receptor CCR-9) (Chemokine-binding protein 2) (Chemokine-binding protein D6) (O00590)
Organism: Homo sapiens (Human)
Function: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines including CCL2, CCL3, CCL3L1, CCL4, CCL5, CCL7, CCL8, CCL11, CCL13, CCL17, CCL22, CCL23, CCL24, SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3. Upon active ligand stimulation, activates a beta-arrestin 1 (ARRB1)-dependent, G protein-independent signaling pathway that results in the phosphorylation of the actin-binding protein cofilin (CFL1) through a RAC1-PAK1-LIMK1 signaling pathway. Activation of this pathway results in up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. By scavenging chemokines in tissues, on the surfaces of lymphatic vessels, and in placenta, plays an essential role in the resolution (termination) of the inflammatory response and in the regulation of adaptive immune responses. Plays a major role in the immune silencing of macrophages during the resolution of inflammation. Acts as a regulator of inflammatory leukocyte interactions with lymphatic endothelial cells (LECs) and is required for immature/mature dendritic cells discrimination by LECs.
Subcellular location: Early endosome. Recycling endosome. Cell membrane; Multi-pass membrane protein. Note=Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via clathrin-coated pits. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane.
Interaction partners:
- C-C motif chemokine 25
- C-C motif chemokine 27
- Mucosal addressin cell adhesion molecule 1
- C-C motif chemokine 21
- C-C motif chemokine 17
- C-C motif chemokine 2
- C-C motif chemokine 5
- C-C motif chemokine 3
- C-C motif chemokine 22
- C-C motif chemokine 19
Sequence:
MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMTGMNDLGERQSENYPNKEDVGNKSA
Protein: Eukaryotic translation initiation factor 6-1 (AteIF-6;1) (O22290)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03132}. Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03132}. Note=Shuttles between cytoplasm and nucleus/nucleolus. {ECO:0000255|HAMAP-Rule:MF_03132}.
Interaction partners:
- At1g43860
- Ribosome assembly factor mrt4
- Transducin/WD40 repeat-like superfamily protein
- Ribosome biogenesis protein BOP1 homolog
- 60S ribosome subunit biogenesis protein NIP7 homolog
- Ribosome biogenesis protein WDR12 homolog
- Probable rRNA-processing protein EBP2 homolog
- At4g01560
- Pescadillo homolog
- AT5g20600/F7C8_190
Sequence:
MATRLQYDNNNCEIGVFSKLTNAYCLVSATSASANFFTGYESKLKGVIPIVTTSIGGSGTIGSLCVGNKNGLLLSHTITDQELQHLRDSLPDEVVVQRIEEPICALGNAIACNDYVALVHPKLEKDTEEIISDVLGVEVYRQTIANNELVGSYCSLSNNGGMVHSNTNVEEMVELANLVQVPLVAGTVNRGSQVISAGLTVNDWTAFCGSDTTAVELSVVNNIFKLVQSQPDFVGSEMRKSLIDTYV
Protein: P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) (Q9JJX6)
Organism: Mus musculus (Mouse)
Function: Receptor for extracellularly released ATP acting as a ligand-gated ion channel that plays multiple role in immunity and central nervous system physiology. Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation. Participates also in basal T-cell activity without TCR/CD3 stimulation. Promotes the differentiation and activation of Th17 cells via expression of retinoic acid-related orphan receptor C/RORC (By similarity). Upon activation, drives microglia motility via the PI3K/Akt pathway.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q99571}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F8W463}. Lysosome membrane {ECO:0000269|PubMed:27477609}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- P2X purinoceptor 6
- P2Y purinoceptor 6
- P2X purinoceptor
- P2X purinoceptor 3
- Toll-like receptor 4
- P2X purinoceptor 2
- P2Y purinoceptor 12
- Pannexin-1
- P2X purinoceptor 7
- P2Y purinoceptor 2
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIPDKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAGHSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKRYYYRDKKYKYVEDYEQGLSGEMNQ
Protein: Fms related receptor tyrosine kinase 3 ligand (A0A0G2K6K8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSPKSALLSLPRPCHRHEGSPAEMTVLAPAWSPNSSLLLLLLLLSPCLRGTPDCYFSHSPISSNFHMRISELTDYLLKDYPVTVAINLQDEKHCKALWSLFLAHRWIEQLKTVAGSKMQKLLEDVNTEIHFVTSCTFQPLPECLRFVQTNISHLLQDTCSQLLALKPCIGKACQNFSRCLEGLIVQARLTLNSKQSSCLSVLSSGITDSSTLLPPESPGALGATELPKPQPRQLWLLLLLPLTVVLLAAAWCLRWQRTRRRVELRPGVPLPSHP
Protein: Magnetosome protein MamT (Magnetochrome MamT) (Q2W8P5)
Organism: Paramagnetospirillum magneticum (strain ATCC 700264 / AMB-1) (Magnetospirillum magneticum)
Function: May play a role in magnetite crystal maturation (Probable). May transfer electrons to balance the Fe(2+)-Fe(3+) ratio during magnetite formation (Probable).
Subcellular location: Magnetosome membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Magnetosome protein MamS
- Magnetosome protein MamR
- Magnetosome protein MamB
- Multi-heme protein MamP
- Probable membrane transporter protein MamO
- Magnetosome protein MamQ 1
- Magnetosome protein MamM
- Magnetosome protein MamN
- Magnetosome formation protease MamE
Sequence:
MSMEAPRRGRRWVSLGMIALLAAIGLGLYWDQLSTPSGITPATSPRRAEGLLLGRLPLPMEPSLLSPLERLLEPPLRYKLMTIRHIPPVKPGTGMPHPYVGDCIQCHLMVGGPAAGSQFKTPYGAVLENLSRVRKLGPPILPTSRQPHPPAGRCIKCHDIVVKVPVDKKGGMRWQL
Protein: Intraflagellar transport protein osm-1 (Osmotic avoidance abnormal protein 1) (Q22830)
Organism: Caenorhabditis elegans
Function: Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for the maintenance and formation of chemosensory cilia that detect chemosensory cues.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:10545497}. Note=Emerges from the transition zones and move in a bidirectional fashion along the sensory cilia, displaying anterograde movement from the transition zone toward the tip of the ciliary axoneme and retrograde movement from the cilium tip back toward the transition zone.
Interaction partners:
- Intraflagellar transport protein 88 homolog
- Intraflagellar transport protein che-13
- Intraflagellar transport protein 52 C-terminal domain-containing protein
- Tetratricopeptide repeat protein 30 homolog
- TRAF3-interacting protein 1
- CHE-2 protein
- Intraflagellar transport protein 46 homolog
- Clusterin-associated protein 1 homolog
- Intraflagellar transport protein 56 homolog
- Intraflagellar transport protein 81 homolog
Sequence:
MKLKYLSTILPAQDGEAKISNISCSPNGSRAAIACSDRSVALLDENGVQKDRFTCKPIDAKYGKKSFTVLCMTFSPDSSRIAIGQSDNVLFIYKVGTSWNEKKVIVNKFVQPSAVTCLSWPFDDKILVGQLDGKVRIGLIKTNKCSSLYKTDETVVSIQTHPKRTSFVSAHQDGSIILYNFSSRTQSKICTLQVPPYNLVFTNHGLVVATSDRRVLSYTENGVVQQQFDYNDQSEKEFSSISCDPTAQNVVVASYDRLRLFSWSARRGAWDEGAPLEIQNAYTIGALGWKMDGSTIYAGTVCGGVFSVDCCLRRGMLKSRFETTYVAPSHVILRDVTNDTRTNVISNKGLAIDELKIMGKDRYVIGYTSSSIIIADTESQRFSELEWQSGGHEKFYFDFNNCCLIINAGEVTVVEYGVDGSLGWVRTELTSPHLLSVQVSGPDVEEHKKVKKLAYLVDPTTISIINLINGQQESFINHTGAVDWIELNERASKLLYRDKRSKVTLVDISSDQRSVLLSFCTYVQWVPMSDVIVAQSGDNLSIWYNPDLPEQVTNMKIKGEVEAVLRDADRTEVIVQEPTAKVAYELDNTQIEFGAALEKRDFDRAVAFLESNTSGTDAYSMWIRVAEMALEHGNLFVAQRCYAAINDVAKVRKLHDILEIADEASISIGGDGTHFYKVRAMLAIMGRKFKEAERIFLEQNDTESAIGMYTSLHKWDEALELAKVLNYPEYEQLKTSYLRALSDTGQDSKAAELKVSDGDTLSAIQLYIKSNKPLSALSAANNDSVLSQDENILRQIADSLVKSQLYDKAGDVYEKLKDFDKAVEYFKKGDAYGKAIQLARFAFPEKVVTLEQEWGLHLEYIGQYDAAVNHFVEANDLKKAVEAAIRAKEWPKALSIVENIQDQKVRTGYYGEIADHYSNKGDFERAERLFVEAGLFNDAIMMYGKNNKWIDAFRLSEEFHGREATISSYLAKAEDLDEHGRFAEAEQLYITIGMPHKAIQMYDRVGRDDDVLRLVERYHGEHMHETRKRFATQYEERGDLKAAEEQFLKAGDFRSAVNMYKDSEMWSDAYRIAKTEGGENMEKQVLFMWAKSIGGDAAVKLLNKHGMLMEGIDFACETGAFDLAFDLARIGAKDRMGTVHVRLATQLEEEGRLEDASKHYVEGNKPELAVEMFIRDNDWADAERVAKDHCESLLPDVYTGQARRAIEEGDHLRAETFLLRANKPDIILRYFIENEMWPDALRIAQNYLPHQAALIQEEYEKSELRNGARGVDSFVAQAKEWEQQGDWRKAVSALLKINRDSTDNDALIKHSTEKAADLVMKFLMGDEEYIGAALGALDEANCNEKAAELLLLFGQSRQAINALCRAKQWAKAKQVAQEYLPEMVPEIEKIYKESLKSEGRLGELIDVDVITAIDMMIENDQWDKALDTAKSQNYRPLLDKYVAQYAAILVHRNDLSRVLAVLERYGASANPANFSIYKLLMEETLAKPRFDYTEIARVRNVHLDVYNALQKESSEHFEEFSRALWALHLIAMRTALEEIGDSVPEVQKLCLKQSLSLLRYTDILVADRIFYEAGAAAKDYGSEYESLGFLLLNHYLDLVDAIEEGNGELVDYSPFENSDIPTEVSLPTRQWLESAKHEEMKEWVLASSVDDAHAKELVYDKRGVFEASLKDKRGTAEPCLVTGYPVIESTVRIGSMVAEKDNLNKFLVVIKSNQTENLLNVQNFVAKWAGSPLAISL
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (Q1LUZ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- GMP synthase
Sequence:
MIKDVLLCLCLFVAPIWCAPVKEDSGPVVVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEYSSMCLQDPNIVPKYAKSMTLELPPTGVSEDCLYLNVYTPSQRSESDKFPVMVWIHGGALVIGGACMYDGTPLAAYEKVVVVVIQYRLGILGYLSTGDQHAQGNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYSFKDPLTYAKVIANITECDFSSSEVLVKCIREMTEEQIIKAAQKKYRLPGATVDGEFIKAQPEEILKSKDFPKIPILVGTTNHEFGWTLSHAILPKDWAKGMDAKSAKQTLDFFYNAGASEANGIIADEYFKNAKTPEEIRDAFTELLGDIIMVIPSIKVASYHRDAGAPVYMYEFQHGPSIANKFRPSFVKADHGDEIGFMFGACFWDGQVKVTGTLTEEENQLCRTVMKYWANFVRTGSPNPAPVPWPVYDQSNKYLNLGLQQTEGQGLKKDKLLFFTEELPKKLAALHTA
Protein: Calsyntenin-1 (F1R520)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9EPL2}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9EPL2}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9EPL2}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9EPL2}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9EPL2}; Single-pass type I membrane protein {ECO:0000255}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q9EPL2}. Note=Localized in the postsynaptic membrane of both excitatory and inhibitory synapses. {ECO:0000250|UniProtKB:Q9EPL2}.
Interaction partners:
- Kinesin light chain
- Zinc finger protein 609a
Sequence:
MRIRGVKPFASAVGLLLGLLYAVDAAKVNKHKPWIETTYHGIVTENDDKVLLDPPLIALDKDAPLRYAGEICGFRIHGQNVPFEAVVLDKSTGEGVIRAKDKLDCELQKEHTFTIQAYDCGEGPDGGNMKKSHKATVHIQVNDVNEYSPVFKEKSYKATVIEGKKYDSIMKVEAVDADCSFQFSQICSYEIVTPDVPFTIDKDGNIKNTEKLNYGKERMYKLTVTAYDCGKNRASEDVLVKINIKPTCKPSWQGFNKRIEYEPGTGSLALFPSMHLETCEEPITSIQASIMLETNHIGKGCDRDTYSEKSLHKLCGASSGTVELLPAPSNSANWTVGLPTDNGHDSDQVFEFNGTQAIKVPEGVVSTTLKEPFTISVWMRHGPGGREKETILCNSDKTEMNRHHYSLYVHNCRLVLLLRQEPTESESYKPAEFHWKLDQVCDKEWHHYVLNIEFPAVTLFVDGGTFEPFLVTEDYPLHTSKIETQLTIGACWQGGSARMTQFFRGNLAGLMIRSGKLENKKVIDCLYTCKEGLDVQLPEEVASAVKVEFNPNQSSLSLEGDDIESFEKVMQHISYLNSRQFPTPGIRHLRVSTTVKCFNEETCISVPDSEGYVMVLQPEEPKISLSGIDHFARGAAEFESVEGVTLFPELRIVSTITREVEVEAEAETEAEGEDDPTVQETVVSEEIMHNLDTCEVTVVGEDLNGDHESLEVDLAQIQQRALEMSSSNVGMVITGVNTMANYEQVLHLIRYRNWHTEALFDRKFKLVCSELNGRYISNEFKVEVNVIHTANPMDHANNAMVQPQFISQVQHASVDLSGHNLVNTHQASVVPSAATIVIVVCVSFLVFMIILGVFRIRAAHQRTMRDQENGKENEMDWDDSALTITVNPMETYEDQHSSEEEGDEEEEESEDGEEEDDITSAESDSSEDEAGEQEDQQGSSRQQQLEWDDSTLTY
Protein: Probable helicase D10 (EC 3.6.4.-) (Protein D10) (P11107)
Organism: Escherichia phage T5 (Enterobacteria phage T5)
Interaction partners:
Sequence:
MKVVISNKAYFKPDDELWDYCSKQTTYHIETMTSKYPIMYKNSGVVAKEIKWIPITRLDLLDAKGIKYELVDKRTLAPVDIPKPKFKLREEDQLPIYEECDDTCIINGKPGFGKTILALALAYKFGQKTLVICTNTSIREMWAAEVRKWFGFEPGIIGSGKYNIDPPIVVSNIQTVNKHANNLSKVFGTVIVDEVHHCVATTFTNFLEISCARYKIGLSGTLKRKDGLQVMFKDFFGYKIFSPPVNNTVAPTIHRYSVPVELSGNQNVPWALRANDVYNHPEYRETIINLAHLYVNMGHKVLIVSDRTELIQTILEALTQRGVTTYEIIGATHLDDRLKIQEDIAKGGPCVLAAAQSIFSEGISLNELSCLIMGSLINNESLIEQLAGRVQRIVEGKLDPIVVDLIMKGGTGLRQASGRMAVYRNNGWKTITMTPEKAVQLAKIAFGNSS
Protein: (-)-beta-pinene synthase 1, chloroplastic (EC 4.2.3.120) ((-)-alpha-pinene synthase (-)betapin1, chloroplastic) (EC 4.2.3.119) (Terpene synthase (-)betapin1) (PbTPS-(-)betapin1) (R9QMR0)
Organism: Pinus banksiana (Jack pine) (Pinus divaricata)
Function: Monoterpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens. Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (-)-beta-pinene and, to a lower extent, to (-)-alpha-pinene.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MDLISVLPSASKSCVCLHKPLSSSTHKLKPFCRTIRILGMPRPRKSVLMVSSMSISVNTLVSDDAVQRRTGGYHSNLWNDDVIQFLSTPYGELAYRERAERLIDEVRNIFNSMSLEDGEFSDLIIQRLWMVDNVERLGIDRHFKNEIKSALDYVYSYWSQKGIGCGTKSIITDLNSTALGFRTLRLHGYPVSADVLKHFRNQIGQFVSCPSETEEDIRSMVNLYRASLIAFPGEEVMEEAESFSEKYLKETLQKIPDCSLSREIGDVLEHGWHTNLPRFEARNYIDVFGQDTKNMESNRKTEKLLELAKLEFNIFQSIQKTELESLLRWWNDSGSPQITFTRHRHVEYYTLASCIAFEPQHSGFRLGFAKACHIITVLDDMYDLFGTVEELKLFTAAIKRWDPSATDCLPQYMKGIYMMVYNTVNEMSAEAQKAQGRDTLNYARQAWEVYLDSYVQEAKWIATGYLPTFEEYLENGKVSSGHRVSALQPMLTMDIPFPPHILKEVDFPSNLNDLACAILRLRGDTRCYQEDRARGEETSCISCYMKDNPGATEEDALNHLNVMISGVIKELNWELLKPDSSVPISSKKINFDITRAFHYGYKYRDGYSVSSVETKSLVMRTLLEPVPL
Protein: Mitochondrial F-box protein MFB1 (Q04922)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Mitochondrial distribution and morphology protein 30
- Mitochondrial distribution and morphology protein 36
- Nuclear migration protein NUM1
- Mitochondrial MYO2 receptor-related protein 1
- Protein TOM71
- Suppressor of kinetochore protein 1
- Mitochondrial import receptor subunit TOM70
Sequence:
MTLFSCSVQMPLEERSLTNLPLNLLFRILSHLDMNDLQNIGKTCTLLRMLANENIVYRNAVIGSNGNMWWTKNVLVDVFDVLNFNRKAMKTLNSHNISLVASLRNVQRKYKLGVIDPARKTISYRTNEVESKEKGSVKDLNMDLNEPTEITREQIAHTAILQGMNQFIELNDKAFRTHSADSDDTYIEENNGEIHSLHGLEKNTTFEEDLVKKPPFIPSPTFSNYSRSSTNSVFSSSSPKLLDDDWNNITMDFTKSRDPDYKEMTPTSTESSDSITRLRKSNKVKDKAELFEKLIFRDSRPLKTKKKDNPRLKLSSSLSANDEDFRKIISPPSDILPKVGRRSVSRGYLEEIERHYPDFNGETTNPLAIKRVNSTKIANYEQLIIKENSSNCKGITEKNDENKFQRSHTSPVIELSKPHQRSKLKAVVTDGNKICYRKIELDNPSGSNTNDHVIKRLDANTDFNI
Protein: Tudor domain-containing protein 7 (PCTAIRE2-binding protein) (Tudor repeat associator with PCTAIRE-2) (Trap) (Q9R1R4)
Organism: Rattus norvegicus (Rat)
Function: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Note=Localizes to cytoplasmic RNA granules (By similarity). Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity). According to PubMed:10727952 localizes preferentially on the periphery of mitochondria. {ECO:0000250, ECO:0000269|PubMed:10727952}.
Interaction partners:
- ATP-dependent RNA helicase TDRD9
- Piwi-like protein 2
- Piwi-like protein 4
- Nanos C2HC-type zinc finger 1
Sequence:
MLEADLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVVRIEASRSGEIVCYAVACTETARIAQLVARQRTSKRKTGRQINCQMRVKKTMPFFLEGKPKATLRQPGFASDYSISKKPNPTLLREKGSTLGAKADVDMPPYPDAPVQRHVSMSANSSVTVLRSHPEASKLQFMGYSPKPHCLLLFSPKSSLPAPFQTHISRACPKEVNDNLNQTVEKPNVTPPASYTNKMDEVQNRIKEILDKHNNGIWISKLPHFYKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGGQDLLLYPAKREQPLRSDQDPEKERPPPPPAPRQEVPSKGSPAVMPDVKEKVAELLGKYSSGLWASALPKAFEDMYKVKFPEDALKNLASLSDVCTINYISGNTQKAILYAKLPLPTDKILKDEAQAQGDFDIKSMIEQEYLQIEKNMAESADDFVEDITVPPLVIPTEASPSVLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEYYSRNPRVTPIQTVHVGQLLAVNAEEDAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSFQATKCKLAGLEILNDDPNLVKVVESLTCGKIFAVEILDKSDIPLVVLYDTSGEDDININATCLKAICDRSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDEARGVAYVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAVSAAASSPGNRNASTPAPGSPAESLRKSHPEVLRKSVLDHTSSFSLEELPPPVHLSKSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVERDQVYAAKVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDVFRKLPFQAVTAQLAGVKCSQWSEEASMVFRNHVEKKPLVALVQTVIEHANPWDRKVVVYLVDTSLPDTDTWIHDFMSQYLVELSKAN
Protein: Hypothetical MGC50722 (Q8IVT4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPTLVVGTPPTCLGDTPQPCHKNSQRQGPFSHGAPGRAADWKAVAKPRLCAPAAEDDVAALRWPGPSQQPDPPWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDGDSSVSSGRLSCSSGGHDVCVSWKERPPQVLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSASRLHKASTLTLRRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQVPVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGPPPVLRRHHSKDPSRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVSGNTPSLASFDQPATIQTAMAILQDLRQQIQAGLELAQARKGGQELGPSKRRLQDVAGRGRCRDPNAQSSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKASALRTRELRSRRLQEVYRQQREAVLGRAVPVVSRTTPGIVTFVPSSAQSGGLEASGSLESPVLEWSKVTSGMVLGGQEAPGSFCLCLNRAWNHAETLDPPGMGGPQDGRDAPVLLSASPSLGSLELQDLTTRYLPRGMCIYLDPKEAEHLGTSSSLHLRHKQAQLQALETTAKVLKQRVDSLTAKLQGAEAPDTVRDPAVGLLRSCPHSLPAAPTLATPTLATPACPGALGPNWGRGAPGEWVSMQPQPLLPPTYFLEGETLSWGPSWEQQQSVSPRAHCESKPRGVSQAPLLL