wanglab/gogpt-training-data huggingface dataset:
Protein: mRNA export factor mex67 (Q9Y8G3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the export of mRNA from the nucleus to the cytoplasm.
Subcellular location: Nucleus {ECO:0000269|PubMed:14963046}. Cytoplasm {ECO:0000269|PubMed:14963046, ECO:0000269|PubMed:16823372}. Note=Localizes at both the nuclear and cytoplasmic site of the pores (PubMed:14963046). Shuttles between the nucleus and the cytoplasm (PubMed:14963046). {ECO:0000269|PubMed:14963046}.
Interaction partners:
- Poly
- NTF2-related export protein 1
- mRNA export protein mlo3
- Nuclear cap-binding protein subunit 2
- Uncharacterized RNA-binding protein C106.12c
- Nucleoporin nup189
- mRNA export factor gle1
- Exportin-1
- ATP-dependent RNA helicase uap56
- Nonsense-mediated mRNA decay protein 3
Sequence:
MLRRKRERRNAVKENEMVIDTPLEKRRTPGKPRATREPPISVVITGHSKGSEDDLISFVWRKVKVRLMNISYSPASVTAVVKSQDFSRLNGLNGAAFAGDHLAIRRVDGASNVTQDYRKAKTKRSFRSVSAPSLSALATQAQRNVSKTLPQSTNETIEKLRQFLQTRYQPATKFLDLGNLQQDPLLKQMGILAEASTKSKMFPALMKVASLNFPDVISVSLSDNNLQSVTAVTTLAQTWPKLLNLSLANNRITSLSDLDPWSPKTKLPELQELVLVGNPIVTTFANRAMDYQREMVSRFPKLRLLDGNSINSEIIASQSTVPFPVYQSFFDKVETEQIVNSFLAAFFKGWDENRSALVNQLYSPNATFSISLNASNVRTNFSQKTDTKKWGAYKMKSRNLLYSQSQKESKSRLFNGHEEISNAVKSLPATAHDLSDRSQWVFDGWNLVLPSVGAAIKIVVHGQFEEPQNKRLLRSFDRTLLILPGGSTGILIINDLLVIRSFAGSLGWLPGQSSVRTSNNAMSASASKPSDIVQPRPEQAMLDTRQQIVLKIKAETGLNDYYAHMCCEQNNWDYNSALASFLELKSRNVIPAEAFS
Protein: Candida glabrata strain CBS138 chromosome C complete sequence (Q6FX18)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Lanosterol 14-alpha demethylase
Sequence:
MTADIEDTKAKAIGKRSKEIELIEVNGKRVSKTSTGKRKFHKKSKTGCDNCKRRRVKCDEGKPGCKKCSNLNLVCVYSTVVDNKVAKKTTSRKGKSPGANSLENSDDNTRRSVSPQLSQSTPDTKVNTELSGVSDKNSLVQSPVLPNISNTPLSAEALLNGKLGNIALQLQEHANIAASETAYPTTVNNTHGQANSTAKIVQEQRRLLEQLSPSLNLLTPERNSVSSPGATTGTESNLLSQILAGLFGQQQTAAGVSSNTQQQQQQQPLQQLLQHLQPPVMQQNGLQQPSNYRERLPSISMDLNGSPGLQYNTPSTTNNATTNTLLNSILASTLNPISLGKGSTSAVQANSSDGLMGATSTRNEDSIGNALPFSTDAISQLTKLNLNSFPTAGIGGISYDFHELFGIKYNHTNNRAIKVSSAEEALANMQEHREREQASKISEKQKQAAEQETRNSENGVINKQNSIGINASSENSVSASSVSENFLNSTSTAEQQYTNLGNDVSNLINLKDVAPLNGNDNMNMMSPLIKSSLDKSAVPENPGNDLLNTKSPSTFDGISMDMVQNQTTERKNENNNGSIGRNNSSNNISMTPLNTNTTSSGISDFAGKTASPSIPHLIELSSKTSLGLVDLKLFHHYCTEVWPTIIAVGISSPEVWGTYLPDLAFKYPFLMHSMLAFSATHLSRTQPGLDDYVASHRLSALKLLREAVLEISDDNTDALVASSLILIMDSLANASNSNPTAWIFHVKGAVTILTAVWPLPETSKFYNLISVDLSDLGEIVDKDTGTITELVCCDDDIADLYPVDLDSPYLITLAYLDKLYREKNQLDYILRVFAFPALLDRTFLTLLMTGDLGAMRIMRSYYKLLRNYTTEIMDRAWFLEGVSQVLPRDVDDYSGGGGMHMMLDFLGGGLPSMTTTNLSDFM
Protein: Nuclear receptor subfamily 1 group I member 3 (Constitutive androstane receptor) (Q9DFH3)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MSQSSPSDPDSPGAQRCPNVTDVTEEELKVCAVCGDRATGYHFHVMSCEGCKGFFRRSILKGVHFTCPFTRSCPITKAKRRQCQACRLQKCLDVGMRKDMIMSEEALGRRRALRLQRRLAQAQPGGLTAEQQELISILIAAHKRTFDSSFSQFQHYQPAVRLCIPGPCSQSPPGPGVPSASLSPQLDCLDEDVLPDVFSILPHFADLSTFMIQQVIKFAKEIPAFRGLPIDDQISLLKGATLGICQIQFNTVFNEETNAWECGQHCFTIKDGALAGFQQIYLEPLLKFHISLKKLRLHEAEYVLLVAMLLFSPDHASVTQRDFIDQLQEKVALTLKSYIDHRHPMPEGRFLYAKLLLLLTELQTLKMENTRQILHIQDLSSMTPLLSEIIS
Protein: Tyrosine decarboxylase (EC 4.1.1.25) (Q95ZS2)
Organism: Caenorhabditis elegans
Function: Required for the decarboxylation of tyrosine to tyramine, a precursor of octopamine but probably also itself a neurotransmitter. Involved in the regulation of egg laying, which is inhibited by tyramine. Also involved in controlling locomotion and head movements. Due to its involvement in octopamine biosynthesis, also required for crtc-1-dependent regulation of AMPK-mediated longevity which requires octopamine signaling.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15848803}. Cell projection, axon {ECO:0000269|PubMed:15848803}. Perikaryon {ECO:0000269|PubMed:15848803}.
Interaction partners:
- Tyramine beta-hydroxylase
- Tyrosine 3-monooxygenase
- Tyrosine aminotransferase
- Biopterin-dependent aromatic amino acid hydroxylase family profile domain-containing protein
- Aspartate aminotransferase
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase
- Aromatic-L-amino-acid decarboxylase
- Aromatic-L-amino-acid decarboxylase
- Phenylalanine-4-hydroxylase
Sequence:
MVYGLGEALKNLNSYCQERTTRIRNSLSPSRPSMSEATATGSSSSSRASTTIPSTPNMDVTPTVEDPRQNDNNASGMTRDEFRQYGKETVDYIVDYLENIQKRRVVPAIEPGYLKDLIPSEAPNTPESFESVMEDFEKLIMPGITHWQHPRFHAYFPAGNSFPSIIADMLSDAIGCVGFSWAACPAMTELELIMLDWFGKMIGLPAEFLPLTENGKGGGVIQSSASECNFVTLLAARFEVMKELRQRFPFVEEGLLLSKLIAYCSKEAHSSVEKACMIGMVKLRILETDSKFRLRGDTLRNAIQEDRNLGLIPFFVSTTLGTTSCCSFDVLSEIGPICKENELWLHVDAAYSGSAFICPEFRPLMNGIEYAMSFNTNPNKWLLINFDCSTMWVRDRFKLTQALVVDPLYLQHSWMDKSIDYRHWGIPLSRRFRSLKLWFVIRMYGIDGLQKYIREHVRLAKKMETLLRADAKFEIVNEVIMGLVCFRMKGDDELNQTLLTRLNASGRIHMVPASLGDRFVIRFCVCAENATDKDIEVAYEIIAQATQHVLHDSVKAVIAEEDEEAVALEEMVADLNITETPEKCLTRQNSANAAESGQKLERQLSKEEILAQKQHESLAKKRSFLVRMVSDPKCYNPKIVRHLNMANHRKMSQDLYRDRTLMQTISHSQRPNRLSQSPGSAGSAFFDDDDDRIVADVQTGLQTPI
Protein: Lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform A (Lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform B (EC 1.5.1.7)) (Q9VLX0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- aldehyde dehydrogenase
- Spermidine synthase, isoform A
- Vanin-like protein 1
- General transcription factor IIF subunit 1
- 10-formyltetrahydrofolate dehydrogenase
- Acyl carrier protein, mitochondrial
Sequence:
MWRVIQLRATIAHPFTRQRHSRVIAIRREDQSVWERRAPFGPTHVQKLVKQNVKVIVQPSNRRAYPMQAYMQAGAHIQEDISDASVIFGVKQVPIDALIPGKTYCFFSHTIKAQESNMPLLDAILEKKIRLIDYERIIDERGARQVAFGKYAGVAGMVNILHGIGLRLLALGHHTPFMHIGPAHNYRNSSMARQAIRDCGYEISLGMMPKSIGPLTFVFTGSGNVSQGAQEVFSELPIEYVPPEMLRKVAEHGNQNKLYGCEVSRSDHLERREGGGFDAKEYDEFPERYISTFSTKIAPYASVIVNGIYWAVGSPKLISIPDAKNLLRPANTPWLPTSKGSPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKSFKGPGVLVCSIDNMPTQLPRESTDLFGELLAPHVHDIIKSDAKKPLAEENFSYPIQSAIIASNGQLTEGFQYIQELRESQSHRSRHKMEGSSESDKKVLVLGAGMVSAPLVEWLHREKDVSITVCSQVKEEADRLAQQYAGVDSVYLDVNESTGHLQELCGRADVVVSLLPYSLHGMVARYCVAEGTHMVTASYLNDEISGLHEEAKAKGVTIMNEVGLDPGIDHLLALECIHEVQDKGAVVESFVSYCGGLPAPEHSNNALRYKFSWSPRGVLLNTLSAAKYLSQGQIVEISGGGELMSSPRSLDFLPGFALEGFPNRDSTKYGNLYGLGRDVHTLLRGTIRYKGFSESIKPMQLLGLIDPEPHALLHPSGPDVTWRQLVIHLMGMSDSTIFYENLKQKLTERIGDVDGIESLGLLDDTPVVKLNTPLDTLSHYLSKRLAFERDERDLVVLRHEVGIRWPDGRREERGINFVVYGQPQGHSAMAMTVGKPAAIAAKMILDGEIQERGVLLPFTPDIYRPMLQRLRSEGLTATETSRWLN
Protein: Transcription factor HES-7.1-B (HES-related protein 1-B) (XHR1-B) (Hairy and enhancer of split 7.1-B) (Q8UW72)
Organism: Xenopus laevis (African clawed frog)
Function: Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters (By similarity). Demarcates the prospective midbrain-hindbrain boundary (MHB) region in the neuroectoderm in early gastrulae embryos by repressing transcription of a number of target genes.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8BKT2, ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
Sequence:
MKGTSEVKPMETHRKLLKPLVEKRRRERINNSLEKLRIFLSQTLKSEKLKNPKVEKAEILECTVQFLQSRKLLPLDREAVDKEYQSGFQHCLETTLHFMNSKPDMNGVTKELLSHQMSSCKPPSDAWSPTCAPLTKHVPSLSYQDSTPHLVSNSISISPTKTLVDSHFTYQTFKTWRPWV
Protein: Pituitary homeobox 3 (Homeobox protein PITX3) (Paired-like homeodomain transcription factor 3) (O75364)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. Acts by decreasing the interaction of NR4A2/NURR1 with the corepressor NCOR2/SMRT which acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state. Essential for the normal lens development and differentiation. Plays a critical role in the maintenance of mitotic activity of lens epithelial cells, fiber cell differentiation and in the control of the temporal and spatial activation of fiber cell-specific crystallins. Positively regulates FOXE3 expression and negatively regulates PROX1 in the anterior lens epithelium, preventing activation of CDKN1B/P27Kip1 and CDKN1C/P57Kip2 and thus maintains lens epithelial cells in cell cycle (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}.
Interaction partners:
- Nuclear receptor subfamily 4 group A member 2
- Forkhead box protein E3
- Phakinin
- Gap junction alpha-8 protein
- Gap junction alpha-3 protein
- Gamma-crystallin D
- Beta-crystallin B2
- Pituitary homeobox 2
- Gamma-crystallin S
- Tyrosine 3-monooxygenase
Sequence:
MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
Protein: Transcription factor JunD (Transcription factor AP-1 subunit JunD) (P15066)
Organism: Mus musculus (Mouse)
Function: Transcription factor binding AP-1 sites (By similarity). Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence 3'-TGA[GC]TCA-5' and enhancing its transcriptional activity (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Protein c-Fos
- Transcription factor Jun
- Fos-related antigen 2
- Protein FosB
- Fos-related antigen 1
- Transcription factor JunB
- Menin
- Stress-activated protein kinase JNK
- Mitogen-activated protein kinase 9
- Cyclic AMP-dependent transcription factor ATF-3
Sequence:
METPFYGEEALSGLAAGASSVAGATGAPGGGGFAPPGRAFPGAPPTSSMLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSTQFLYPKVAASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAPPAPADLAATPGATETPVYANLSSFAGGAGPPGGAATVAFAAEPVPFPPPPGALGPPPPPHPPRLAALKDEPQTVPDVPSFGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY
Protein: Cytochrome b-c1 complex subunit 9, mitochondrial (Complex III subunit 9) (Complex III subunit X) (Ubiquinol-cytochrome c oxidoreductase subunit 9) (Q9LXJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P22289}; Single-pass membrane protein {ECO:0000250|UniProtKB:P22289}.
Interaction partners:
- Cytochrome b-c1 complex subunit 7-2, mitochondrial
- Cytochrome b-c1 complex subunit Rieske-2, mitochondrial
- Cytochrome b-c1 complex subunit 6-1, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 7
- Cytochrome c oxidase subunit 6a, mitochondrial
- Cytochrome b-c1 complex subunit 7-1, mitochondrial
- Cytochrome b-c1 complex subunit Rieske-1, mitochondrial
- Cytochrome b-c1 complex subunit 6-2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 9
- NADH dehydrogenase 1 alpha subcomplex subunit 6
Sequence:
MEYAARRNQKGAFEGFYKLIMRRNSVYVTFIIAGAFFGERAVDYGVHKLWERNNVGKRYEDISVLGQRPVEE
Protein: White collar 2 protein (WC2) (P78714)
Organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function: May function as a transcription factor involved in light regulation. Binds and affects blue light regulation of the al-3 gene. Wc-1 and wc-2 interact via homologous PAS domains, bind to promoters of light regulated genes such as frq, and activate transcription. May bind directly to frq.
Subcellular location: Nucleus.
Interaction partners:
- White collar 1 protein
- Frequency clock protein
- Vivid PAS protein VVD
- FRQ-interacting RNA helicase
- Sensor histidine kinase/response regulator
- Phytochrome-like histidine kinase 2
- non-specific serine/threonine protein kinase
- Geranylgeranyl pyrophosphate synthase
Sequence:
MSHGQPPPGSSMYGFGAMGMGSGMGSGMGSGMGTGMGTGMGTGMSASQMTSDPQDMMSLLDTSVFPGFDGMSMSLDVGDSMSNPFTPVSVPPPLPAGNAGPSHVGVCGGHGAPDQLFSPDDLIATSMSSAGPMIATPTTTTSGPSGGPSSGGGSTLTEFTKRRNWPAKVVEELQDWEHILDANGRIKHVSPSVEPLTGYKPPEIIDLFLRDLIHPDDVGVFTAELNEAIATGSQLRLFYRFRKKDGNWTIFETVGHAHIAAAKFAPNPQNQSPFCQAVFMMARPYPTKNAGLLDSFLEHKIENERLKRRIAELRREEQEEQEESHRTWRMSQEGRSDVTPSDDTATQMGMTPFYIPMNAQADVMMPPPSQPASSLNIALTRENLEGIAGSRPDSIREKMLRYEGNHADTIEMLTGLKYQEGERSHGITTGNASPTLIKGDAGIAIPLDRDPRTGEKKKKIKVAEEYVCTDCGTLDSPEWRKGPSGPKTLCNACGLRWAKKEKKKNANNNNNGGGIGGHNDIHTPMGDHMG
Protein: Mitochondrial distribution and morphology protein 12 (Mitochondrial inheritance component mdm12) (Q92377)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
Subcellular location: Mitochondrion outer membrane {ECO:0000255|HAMAP-Rule:MF_03104}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03104}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_03104}. Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03104}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03104}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_03104}. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids. {ECO:0000255|HAMAP-Rule:MF_03104}.
Interaction partners:
- Mitochondrial distribution and morphology protein 10
- Mitochondrial distribution and morphology protein 34
- Maintenance of mitochondrial morphology protein 1
- Mitochondrial Rho GTPase 1
- Dynamin-related protein dnm1
- Probable mitochondrial import receptor subunit tom40
- Mitochondrial import receptor subunit tom7
- Probable mitochondrial import receptor subunit tom70
- Metaxin-like protein C409.19c
- Mitochondrial import receptor subunit tom22
Sequence:
MSIDFDWSKLDSELEAKVLHLLEGQVSNLSLPSYIKHLKVVDFHFGKVSPQITIQEIGDPDPQFYENEAFELANQELEGDQCSRNNVSPVLTDLPPYAAEHPFSRLAYFNPAFNSPGILSASGLTSPIPESRPSTPMDNHQERDRSNDFQVTAHVSYDGDANLSLEAVLSMNYPNSEFAVLPFKLSFIRISIDAIAVLAKMGKRTHLCFVDTLLHGTGEHASSVIRDLTVESIIGESNKQLLKNVAKVEKFVSEKVKRIIEDELVWPSYITIE
Protein: 3-ketoacyl-CoA synthase 8 (KCS-8) (EC 2.3.1.199) (Very long-chain fatty acid condensing enzyme 8) (VLCFA condensing enzyme 8) (Q4V3C9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18465198}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470
- Very-long-chain 3-oxoacyl-CoA reductase 1
- Delta-9 desaturase-like 4 protein
- At1g04800
- Wax ester synthase/diacylglycerol acyltransferase 7
- At2g10940/F15K19.1
- ATP-dependent RNA helicase
- ARM repeat superfamily protein
Sequence:
MKNLKMVFFKILFISLMAGLAMKGSKINVEDLQKFSLHHTQNNLQTISLLLFLVVFVWILYMLTRPKPVYLVDFSCYLPPSHLKVSIQTLMGHARRAREAGMCWKNKESDHLVDFQEKILERSGLGQETYIPEGLQCFPLQQGMGASRKETEEVIFGALDNLFRNTGVKPDDIGILVVNSSTFNPTPSLASMIVNKYKLRDNIKSLNLGGMGCSAGVIAVDVAKGLLQVHRNTYAIVVSTENITQNLYLGKNKSMLVTNCLFRVGGAAVLLSNRSRDRNRAKYELVHTVRIHTGSDDRSFECATQEEDEDGIIGVTLTKNLPMVAARTLKINIATLGPLVLPLKEKLAFFITFVKKKYFKPELRNYTPDFKLAFEHFCIHAGGRALIDELEKNLKLSPLHVEASRMTLHRFGNTSSSSIWYELAYTEAKGRMKEGDRIWQIALGSGFKCNSSVWVALRDVKPSANSPWEDCMDRYPVEIDI
Protein: Fasciclin-like arabinogalactan protein 13 (Q9FFH6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be a cell surface adhesion protein.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
- Fasciclin-like arabinogalactan protein 18
- Fasciclin-like arabinogalactan protein 3
- Fasciclin-like arabinogalactan protein 19
- Fasciclin-like arabinogalactan protein 15
- Fasciclin-like arabinogalactan protein 14
- Classical arabinogalactan protein 3
- Fasciclin-like arabinogalactan protein 21
- At5g05960
- Xyloglucan endotransglucosylase/hydrolase protein 4
- Protein SEED AND ROOT HAIR PROTECTIVE PROTEIN
Sequence:
MATTPLLLLLLTAVFLSTEITAQRAAPAPGPAGPINITAILEKGGQFVTLIRLLNTTQIGNQINIQINSSSEGMTVLAPTDNAFQNLKPGTLNKLSPDDQVKLILYHVSPKFYTLEDLLSVSNPVRTQASGRDVGGVYGLNFTGQGNQVNVSTGVVETRLSTSLRQERPLAVYVVDMVLLPEEMFGERKISPMAPPPKSKSPDVSDDSESSKKAAAPSESEKSGSGEMNTGLGLGLGLVVLCLKFLL
Protein: Alpha/beta hydrolase domain-containing protein 17B (Abhydrolase domain-containing protein 17B) (EC 3.1.2.22) (Q7M759)
Organism: Mus musculus (Mouse)
Function: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Has depalmitoylating activity towards GAP43. Has depalmitoylating activity towards MAP6. Has depalmitoylating activity towards NRAS (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:27307232}; Lipid-anchor {ECO:0000269|PubMed:27307232}; Cytoplasmic side {ECO:0000269|PubMed:27307232}. Recycling endosome membrane {ECO:0000269|PubMed:27307232}; Lipid-anchor {ECO:0000269|PubMed:27307232}; Cytoplasmic side {ECO:0000269|PubMed:27307232}. Cell projection, dendritic spine {ECO:0000269|PubMed:27307232}. Postsynaptic density membrane {ECO:0000269|PubMed:27307232}.
Interaction partners:
- Acyl-protein thioesterase 1
Sequence:
MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVSQELVNL
Protein: Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7) (Q96T83)
Organism: Homo sapiens (Human)
Function: Golgi Na(+), K(+)/(H+) antiporter. Mediates the electoneutral influx of Na(+) or K(+) in exchange for H(+). May contribute to the regulation of Golgi apparatus volume and pH.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15840657, ECO:0000269|PubMed:20364249, ECO:0000269|PubMed:30335141}; Multi-pass membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000269|PubMed:15840657}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:30335141}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium/hydrogen exchanger 6
- KRAB domain-containing protein 4
- Sodium/hydrogen exchanger 9B2
- Carbohydrate sulfotransferase 7
- Small ribosomal subunit protein RACK1
- Zinc finger protein 674
Sequence:
MEPGDAARPGSGRATGAPPPRLLLLPLLLGWGLRVAAAASASSSGAAAEDSSAMEELATEKEAEESHRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYGTPATSGRDKSLSCTQEDRAFSTLLVNVSGKFFEYTLKGEISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTGVNANVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAFALAIRDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGVEEPSEEDQNEHHWQYFRVGVDPDQDPPPNNDSFQVLQGDGPDSARGNRTKQESAWIFRLWYSFDHNYLKPILTHSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREEDSDFILTEGDLTLTYGDSTVTANGSSSSHTASTSLEGSRRTKSSSEEVLERDLGMGDQKVSSRGTRLVFPLEDNA
Protein: Clarin-2 (A0PK11)
Organism: Homo sapiens (Human)
Function: Plays a key role to hearing function. Required for normal organization and maintenance of the stereocilia bundle and for mechano-electrical transduction.
Subcellular location: Cell projection, stereocilium membrane {ECO:0000250|UniProtKB:B2RVW2}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Voltage-dependent calcium channel gamma-2 subunit
Sequence:
MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY
Protein: CDH1 protein (A5D8W4)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, desmosome {ECO:0000256|ARBA:ARBA00004568}. Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
Sequence:
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPAYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPILASQSIGITDMSHCTCPAPQLPAIF