wanglab/gogpt-training-data huggingface dataset:
Protein: Matrix metalloproteinase-25 (MMP-25) (EC 3.4.24.-) (Q3U435)
Organism: Mus musculus (Mouse)
Function: May activate progelatinase A.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
- Proheparin-binding EGF-like growth factor
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Metalloproteinase inhibitor 2
- Metalloproteinase inhibitor 1
Sequence:
MCFPGSQISPARLYYLVSAPWICTGSLTSSRLPRRRESGPLRVPPRSVQAERILRLPAFGLPLLALLLVPLLPVRAQNPDAKVVSMGVEWLTRYGYLPPADPVHAQMQSLEKLQDAIKVMQRFAGLPETGQMDPMTIKTMRKPRCSLPDVLGAAGLVRRRRRYSLSGSVWKKRTLTWSIRSFSQKSQLSPQIVRTLLSYALAVWATESGLTFQEVNSQYQEPDIIIHFARAYHQDSYPFDGSGGTLAHAFFPGEHPISGDTHFDDEETWTFGSTDDNGIDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPATYRLPQDDRDGLQQLYGRVSQNPNARPTRKPLVPPPQPPAMPPDSPATPVPDRCEGNFDAVANIRGEIFLFKGPWFWRLQPSGQLVSPRPAGLHRFWEGLPTHVKVIQAAYARPLDGRIILFSGPQFWVFQERQLEGAARPLVEFGLPPGEDVDAVFSWPHNGKTYLIRGQKYWRYDEVAARPDPGYPRALSLWDGAPFAPDDVTISNTGDTYFFKGTHFWRFAEGSVKAESDSPQPIGPKWLDCPAPNSDPRVTSPPKTTSKTRSCDCHCELNQASEQLSPLLLPLLPLVAGEVFSY
Protein: Amino acid permease/transporter, putative (Q385A1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MAGDGFVDEHQYFEHPRYHIFRQRQETASPIESSADVEGQTNDGEQQFILDKGAPKRSLSVPMLMGLMYAYTTSGAYAIEETVLGGGPLLGIISIVLVPLLMAAPTTIVVAELATAIPSNAAFLMWYNVSFHRVVYFAMVLLTFLLIFIDNALYTVLISEYVCTAVPCSDTISKLLRLGMVLVTYTLNMVGVQAVGKLSIALSIVTVAPFLTLFSMHMIKSNFYLNWPAISYIPPSIDWATFITTTSWNLCGLEQAATVIEQTKAPRRTFIRALAPLLGLAYLTYIPPILTGASIREGLPDLSQWVTGFWSDVAFSVGGVPLRVFMVVASALSAHALLLSSFCTTTQIIAGVAYTEAFPGPINRVLYKRNKRFGTYHWTLTLNAVLSALFGVFLEFGPLVKVDQVLYGLRVLMIFIAFLVIRHRHPHLKRPFRAPFEGKLLYLLIIPMILFAGLIVLGMVESTQSVIVNLSVLGVVMVISLVYCQLVRKEDFYGRIVTGTLSEDEKQ
Protein: Paraneoplastic antigen Ma1 (37 kDa neuronal protein) (Neuron- and testis-specific protein 1) (Q8ND90)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:10050892}. Note=In tumor cells, it is cytoplasmic.
Interaction partners:
- Zinc finger CCHC domain-containing protein 12
- Paraneoplastic antigen-like protein 8A
- Modulator of apoptosis 1
- Paraneoplastic antigen-like protein 6A
Sequence:
MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAMPQVSYRMLGRMFWREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPTPTPGPEMPAEMLNYILDNVIQPLVESIWYKRLTLFSGRDIPGPGEETFDPWLEHTNEVLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDAQIKFLNTYQNPGEKLSAYVIRLEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLWLTGAGEGPAPNLFQLLVQIREEEAKEEEEEAEATLLQLGLEGHF
Protein: Serine/threonine-protein kinase Haspin homolog ALK2 (EC 2.7.11.1) (P32789)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Serine/threonine haspin-like protein kinase involved in cell cycle regulation.
Interaction partners:
Sequence:
MNFDAVADQQMTDRRYFALEVAESDDADSSLNSSSMGSPAVDVGRKVYKITSHKGSAEDESQSFFTSSDSPTSKTRPVGKTIENDDYYGKRSSTGSSLKQLFNKININDTAHSSNKENVSQSVLSENKLLSPSKRLSKQGLTKVTNSKFRTPLRPISNQSTLSRDEPVKDFRSLKFRSGSDFKCWGDEKTSSHVHSSSVNSVNSFTSTTSSSKWKFWKNDNLLSRSLSSRSVNDQDPNFVQPKPTNSLQKKSSISSFHNSIFGGGKHTEKKRNSGFIMPDHQSTKELNHKHSSSNLSFRSLKHKTSHSSLNKLKVRRKGNTQELNHPIKKTCQISLPVPDQVSKDKIQLKLKNSTSLASLSSEVTPINTLDYNDSILQQILQLCDVKYILHDLREAQSLGLFTLNTRSVQLSHNFWQTYHSDMQTSLICKKVCLGALSDLTTSNLISLHELKSLRLIQGTSGVANLLQAYVVPSNQCENDQNLILYLFFKYQGTPLSRCSNIDYSQALSIFWQCSSILYVAESKFQLEHRNLTLDHILIDSKGNVTLIDMKCCRFLNIDNNKASYTRLDHHYFFQGRGTLQFEIYELMRSMLPQPISWATFEPRTNLLWLYHLSSSLLKMAKKAVVSGALNREENILIELTHLLDPARKHSKTIFKKELVIRTCGDLLSLKGEIMQ
Protein: Selenoprotein S (A0A182DWI4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
Sequence:
MMVGSLLATYGWYIVFSCILLYVVFQKLSARLRALRQRQLDRAAAAVEPDVVVKRQEALAAARLKMQEELNAQVEKHKEKLKQLEEEKRRQKIEMWDSMQEGKSYKGNAKKPQEEDSPGPSTSSVLKRKSDRKPLRGGGYNPLSGEGGGACSWRPGRRGPSSGGCG
Protein: Teashirt homolog 1 (Antigen NY-CO-33) (Serologically defined colon cancer antigen 33) (Q6ZSZ6)
Organism: Homo sapiens (Human)
Function: Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Gamma-glutamylcyclotransferase
- Pre-B-cell leukemia transcription factor 3
Sequence:
MPRRKQQAPRRSAAYVPEEELKAAEIDEEHVEDDGLSLDIQESEYMCNEETEIKEAQSYQNSPVSSATNQDAGYGSPFSESSDQLAHFKGSSSREEKEDPQCPDSVSYPQDSLAQIKAVYANLFSESCWSSLALDLKKSGSTTSTNDASQKESSAPTPTPPTCPVSTTGPTTSTPSTSCSSSTSHSSTTSTSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLAPPCSPEPAGMAAEVALSESAKDQKAANPYVTPNNRYGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKIQSIPLPPTTHTRLPASSIKKQPDSPAGSTTSEEKKEPEKEKPPVAGDAEKIKEESEDSLEKFEPSTLYPYLREEDLDDSPKGGLDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKPLPAAVQSVQVQPSYAGGVKSLSSAEHNALLHSPGSLTPPPHKSNVSAMEELVEKVTGKVNIKKEERPPEKEKSSLAKAASPIAKENKDFPKTEEVSGKPQKKGPEAETGKAKKEGPLDVHTPNGTEPLKAKVTNGCNNLGIIMDHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLAMLYKISNSMLDKPVYPATPVKQADAIDRYYYENSDQPIDLTKSKNKPLVSSVADSVASPLRESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNWNPQHLLILQAQFASSLRETTEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYISHLETHLGFSLKDLSKLPLNQIQEQQNVSKVLTNKTLGPLGATEEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYVTELEKQ
Protein: Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein) (Q9D2V8)
Organism: Mus musculus (Mouse)
Function: Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump (By similarity).
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:31142202}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:22820041}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glycerol-3-phosphate acyltransferase 3
- Major facilitator superfamily domain-containing protein 6
- UNC93-like protein MFSD11
- Glycerol-3-phosphate acyltransferase 4
- Putative transporter SVOPL
- Synaptic vesicle 2-related protein
- Protein spinster homolog 1
Sequence:
MGWAGDAGCTPRPPIRPRPASERRVIIVLFLGLLLDLLAFTLLLPLLPGLLERHGREQDPLYGSWQRGVDWFASAIGMPAEKRYNSVLFGGLIGSAFSLLQFFSAPLTGAASDYLGRRPVMMLSLTGLAISYAVWATSRSFKAFLASRVIGGISKGNVNLSTAIVADLGSPPTRSQGMAVIGVAFSLAFTLGPMLGAFLSVEMVPWISLLFAISDMLFIFCFLPETLPQEKRASSVTLGFHTAAHLLSPLALLRFAAVTHSQDPPAEHRLRNLRRLGLVYFLYLFLFSGLEYTLSFLAHQRFQFSSLQQGKMFFFIGLTMATIQGTYARRISPGKEAAAVTRAMLLLVPAFLLIGWAHSLPTLGLGLMLYSFAAAVVVPGLSTMVSSYGSPGQKGTIMGILRSLGALGRALGPVVAASVYWLTGAQVCFTVCSALFLLPFLLLWKLKHPAETSKEE
Protein: Protocadherin 10 (E9PX28)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
MIVLLFFALLWMVDGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARRFQTVANSRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFRVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGGGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAKLTYSILECQIQGMSVFTYVSINSDNGYLYALRSFDYEQIKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRLDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGDRGGGSGEHLRPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGNGSSTCCGRQARARKKKLSKSDIMLVQSANVPSNPAQVPVEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRSTDAEHNPCGAIVTGYSDQQPDIISNGSILSNENKHQRAELSYLVDRPRRVNSSAFQEADIVSSKDSGHGDSEQGDSDHDVTNRGQSAGMDLFSNCTEECKALGHSDRCWMPSFVPSDGRQAADYRSNLHVPGMDSVPDTEVFEPPEVQPGAERSFSTFGKEKALHGTLERKELDGLLSNTRAPYKPPYLNHFHPLSCFAHWK
Protein: Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Palmitoyl protein thioesterase DESI1) (EC 3.1.2.22) (S-depalmitoylase DESI1) (Q9CQT7)
Organism: Mus musculus (Mouse)
Function: Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46. Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22370726}. Nucleus {ECO:0000269|PubMed:22370726}. Note=Shuttles between the nucleus and the cytoplasm; exported from the nucleus in a XPO1/CRM1-dependent manner via its nuclear export signal motifs. {ECO:0000250|UniProtKB:Q6ICB0}.
Interaction partners:
- Ubiquilin-4
- Ubiquilin-2
- Bax inhibitor 1
- 26S proteasome non-ATPase regulatory subunit 12
- 26S proteasome regulatory subunit 6A
- 26S proteasome regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 11
- Proteasome subunit alpha type-1
- 26S proteasome regulatory subunit 4
- Proteasome subunit beta type-7
Sequence:
MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSSGISSCTPGGTLLGPPDSVVDVGNTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPFGQALRPFLDSIQIQPPGGNSVGRPNGQS
Protein: Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) (P16035)
Organism: Homo sapiens (Human)
Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Subcellular location: Secreted.
Interaction partners:
- Matrix metalloproteinase-14
- 72 kDa type IV collagenase
- Matrix metalloproteinase-9
- Stromelysin-2
- Stromelysin-1
- Collagenase 3
- Matrilysin
- Hemopexin
- Interstitial collagenase
- Metalloproteinase inhibitor 3
Sequence:
MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein: Xaa-Pro dipeptidase (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Q9VG79)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Peptidase M3A/M3B catalytic domain-containing protein
- Xaa-Pro aminopeptidase ApepP
- LD05247p
- Dipeptidyl peptidase 3
Sequence:
MAAFQMGSGYAVPMTLFRNNRDRAGKAILKELLPGLKFNDGNLLVLLEGGKDQSLYNTDVDYVFRQESYFQYLFGVKEPGCYGILTIDVKTGAQKSVLFVPRFPDEYGTWMGELLGLQEFKAMYEVDEVFYVDEMSVYLEGASPKLILTLSGTNSDSGLTLQPPDFAGKEKYVTDCNLLYPILSECRVIKSPEEIEVLRYVAKVSSDAHIKVMRFMRPGRMEFEGESLFLHHAYSVGGCRHASYTCICGSGTNSSILHYGHAGAPNSKPVQDGDLCLFDMGANYCGYAADITCTFPANGKFTDDQKFIYNAVLDARNAVTESARDGVSWVDMHKLAGRVLLQRLKEGGMLKGDVEEMLEAGVSGVFQPHGLGHLIGLDVHDVGGYLPKEPKRPSEPWLSKLRFARILKAGMYVTIEPGCYFINWLMDRALADPNIAKFINAEMFNRFRNFGGVRIEDDVLITKTGVENFAIVPRTVEDIEATMTCKYDSPV
Protein: Asp/Glu-specific dipeptidyl-peptidase (EC 3.4.14.-) (Dipeptidyl-peptidase 11) (DPP11) (C2M741)
Organism: Capnocytophaga gingivalis
Function: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has probably a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA.
Interaction partners:
Sequence:
MKRFFKMALFLGVSALYGQQGGMWIPSLLEGMNAKEMKTLGMKMTVADIYSVNKSSLKDAAPHFNGGCSSEVISDKGLLLTNHHCGYGQIQAHSTLQNDYLANGFWAKSLAEELPNKNLKVTFMVRIDDVTKQVLKGTESITDETEKAKLIEKNIAEVIKTAPKEAWQENSVKAFYDGNQYILFVTETFKDVRLVGAPPSSIGKFGSDTDNWVWPRHTGDFSLFRIYADKNNRPAEYSKDNVPYKPKHFFPISLKGVKEGDFVLVFGYPGTTQEYLPSAAVAQIENVINPARIGIRDIVLKVQDSYMRKDQGIKIKYAAKYARVANYWKKWMGETKGLKKSGAVALKQQQEAKFQQAIQKANKQAQYGNLLSDFNRLYKEIEPYTLAANLNSEFIFRNIDLLSNGSRLLQLEKALEDKGEQSFNDRKKNLLNTFKEIFKDNDKQVDKDVFEKVVVFYAANMPKNLLINSLKNFDAKKLADNLYNNSFLTSLSGVESVLNLSAAEFKERMKNDVGIQFVRELKEMNDTQVFPVYDRLNTQIHALQRTYMKAILEFSKPSDRIFPDANGTLRVTYGKVAGFSPADAVTYSAHTTLDGVMEKYVPGDYEFDVPQHLRDLQAKKDFGRYGDKNGKMPLCFLSTCHTTGGNSGSPAIDANGNLIGLNFDRVWEGTMSDIHYDPKLCRNIMVDIRYVLFVIDKYAGAGHLVNEMKLIK
Protein: Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT6) (Q6NZB1)
Organism: Mus musculus (Mouse)
Function: Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates (By similarity). Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a (By similarity). H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3) (By similarity). Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53. Repression of TP53 blocks cellular senescence. Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively) (By similarity). Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity (By similarity). Methylates HMGA1 (By similarity). Regulates alternative splicing events (By similarity). Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1 (By similarity). Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. Methylates GPS2, protecting GPS2 from ubiquitination and degradation. Methylates SIRT7, inhibiting SIRT7 histone deacetylase activity and promoting mitochondria biogenesis (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96LA8}.
Interaction partners:
- Methyl-CpG-binding protein 2
- Histone deacetylase 1
- Histone H4
- Protein arginine N-methyltransferase 5
- Histone H3.3
- Histone H3.2
- Histone H3.1
- Paired amphipathic helix protein Sin3a
Sequence:
MSLSKKRKLESGDSGGAGAGGEGAEEENGGEQEAAPPRPRRTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELPERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPISDQMLEWRLGFWSQVKQHYGVDMSCMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPFHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILLRYKVGDHEEKTKDFAMED
Protein: CCAAT/enhancer binding protein zeta (D3ZNU1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- NOC2-like nucleolar associated transcriptional repressor
- Protein RRP5 homolog
- RNA binding motif protein 28
- Probable ATP-dependent RNA helicase DDX56
- GTP-binding protein 4
- Pescadillo homolog
- Ribosome production factor 2 homolog
- RNA-binding protein 34
- ATP-dependent RNA helicase
- Ribosomal RNA processing 12
Sequence:
MSADQEPLEFLAKNPWRPKEVTEDPDEEDEEDSDEAKNGFSLEEVLRLGGTKQDYLMLATLDENEEVVDGGKKGTIDDLQQGELEAFIQNLNLAKYSKSLIEEDEPEKKENTSKKEAKLPKVENKKQKAAEGKKKNKSVPEQHPESSTVFKAKRDKQPDAFEFLERQALLLKPGGKWYDMEYSGEFSLEPQPWDVVSKYKALAEKLYEQEVGLFKNKTSNQKGGSSTWMKAIVSSGTLADRMAAMILLIQDDAVHTLQFVETLLSLVRKKGSKQQCLMALDTFKELLITDLLPDSRKLRLFSQRPLHKLEELSSGNKDSRDRRLILWYYEHQLKHLVAEFVQVLETLSHDSLVTTKTRALVAAHELLCDKPEEEKALLVQVINKLGDPQNRIATKASHLLEVLLRKHPNMKGVVCGELERLLFRSNISPKAQYYAICFLNQMVLSHEESELANKLITLYFCFFRTCIKKKDIESKMLSAILTGVNRAYPYSQIGDDRVREQVDTLFKVLHVVNFNTSVQALMLLFQVMNSQQTISDRYYTALYKKMLDPGLTTCSKQAMFLNLIYKSLKADIMLRRVKAFVKRLLQVTCTQMPPFICGALYLVSEILKAKPDLRSQLDDHPESDEENFVDVGDDSDDEKFTDADRETATDAVEEVEAKEAEPESSTETEKPKAASWVHFDNLKGGKQIKTYDPFGRNPLFCGAEHTNLWELRKLSQHFHPSVALFAKTILEGNHIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTDSVVMQPKRKHFMKNVRDLAVNSKEFLAKEESQIPVDEVFFYRYYKKVAVTKDKQKRNADEDSIEDVDDEEFENMIDTFEDDNCFTPGKDDMDFASNMKKIKGAKDDLEDSESSDDELGDLDDDEVSLGSMNDEDFEIDEDGGTFMDVSDDESDHVPEFGEASPKASTKKSKRKSEDDFDFAGSFQGQKKKKKSFNDSSLFVSAEEFGHLLDENMGSKFDTTGMNAMANKDNASFKQLKWEAERDDWLHNRDVKSIIKKKKNFRKKKAPQKPKRQRK
Protein: Protein PAM1 (P37304)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known. It is a suppressor of protein phosphatase 2A depletion.
Interaction partners:
Sequence:
MTSALRVLVCGDHPNLILYTSRFQHAKNIEFYLVNNSKNANYEVSSLFYGTERFQIQNHFQSLLDLVDLNNENGGLVFDLIIMSASSLQEIPQVLRDIKPMMNKTTKILFESSGFIYLEPFIKASVDLSLSNIFSIFTDYDIRRLDNGSYKQFTTANAKSFSVSIGQTTSVHENSYSSDIIPILNTFQKLFQKLFPRDVVTLYDHSPSAFLAKEWELALPQICFDPLLIILEEKNPSTLDDHVLAKPLISGLLGESLLIIKKMGIAMNNPNFQNEQTILKHWKNKCEDLPDGPALLYNFIHKASSLNIDLLLLQPILLADDFGVKTPYLECLFTMMTQYQLLNKGDSEWFIRKDENTALTRVDDLQNSIALKDGKIMQLQNSESTLKNEIKELQSQVLSLKQEVSSSKANNGQELEILKKKVQMGDNSLFDRPNSNTNGISPSDNIVDVDLNYERSDQGNNSSGNDSRRQSFFNSTSDTTLSRDETSLKERELEVRMKELELQERELELQRKALQQQQQYQQRPPKQVYSGPSGTPTSGNNNNKSYNPNRKSSYSQPQHVAMMTSRGLHGPSAASSSPVISANNFVDPVSSGTPYSSNSSRFSQQIPSQQYMHTVKPTSRKNRSSVMPNIGYVPGLTNNEYGRKFNGNGMNGTQSRLNSLSNQSTFRSQQGPPITQQKSFQNNGGSMRTNRIPSANYNISNQQSGFVNSISSPNLSNLENRNTVQNSRNADSAPCVNQLNSDSPPQLQSLSQNGTSKVPQINITQPSPIQTNFATSDNPAAVIKLGTPSEDTVSAAATANNISTMGDESRKEDVKEKKKKKFSFFGKRKK
Protein: Sugar transporter, putative (Q385N3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Pteridine reductase, putative
- Phosphomannomutase
Sequence:
MKWRVKIFAALGGFLFGYDTSVINGALFQMKEHFDFPAHSWISGLIVSIAIAGAFVGAFASGFISVRWGRRSCIALADIFFTLGSIMMAFAPNVEVIFVGRAIVGLGIGICSATIPVYLAEITSAGNRGSSIVFNNVCLTGAQFIASVVTALLVQFTGTNFGWRVALGLGAVPSVIQFVGLIFFLPESPRWYLATGRVEKALKTSEMYDIDIVDCAEGGGLVIDYRALFSTVMRRRLLIGCMLHILQQTSGINTIMYYSSVILYDAGFKDPKTPVLLSIPLAAINTLFSLFGVFTVDRWGRRLLLQISACGCFVVTVGMTVVGFMLDKQIPYEIGGWIFLSLLGFYLVFFAPGLGAMPWVVMGEIFPNTLRTSAASVATMCNWGSNALVSQVFPIVLGSIGVGGTFSLLCACIIAAVLFIQFFVVETKGLTLEEIEEMFDPRARHRGSDGSQCSESCSKTERENEGEGTDHGLNQAETARAPI
Protein: Pentatricopeptide repeat-containing protein At1g66345, mitochondrial (Q3ECH5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
Sequence:
MASALRRLVEQQQWRYLVSQSTRSPKLIHGFFSFSSKTNPNPNKQQQILIDYISKSLQSNDTWETLSTKFSSIDLSDSLIETILLRFKNPETAKQALSFFHWSSHTRNLRHGIKSYALTIHILVKARLLIDARALIESSLLNSPPDSDLVDSLLDTYEISSSTPLVFDLLVQCYAKIRYLELGFDVFKRLCDCGFTLSVITLNTLIHYSSKSKIDDLVWRIYECAIDKRIYPNEITIRIMIQVLCKEGRLKEVVDLLDRICGKRCLPSVIVNTSLVFRVLEEMRIEESMSLLKRLLMKNMVVDTIGYSIVVYAKAKEGDLVSARKVFDEMLQRGFSANSFVYTVFVRVCCEKGDVKEAERLLSEMEESGVSPYDETFNCLIGGFARFGWEEKGLEYCEVMVTRGLMPSCSAFNEMVKSVSKIENVNRANEILTKSIDKGFVPDEHTYSHLIRGFIEGNDIDQALKLFYEMEYRKMSPGFEVFRSLIVGLCTCGKVEAGEKYLKIMKKRLIEPNADIYDALIKAFQKIGDKTNADRVYNEMISVR
Protein: Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (C9JE81)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRH
Protein: Protein PET122, mitochondrial (P10355)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for expression of the mitochondrial gene for cytochrome c oxidase subunit 3 (COX3). PET122 seems to work by directly interacting with the small ribosomal subunit to promote translation initiation on the COX3 mRNA.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:8389363}; Peripheral membrane protein {ECO:0000269|PubMed:8389363}.
Interaction partners:
- Protein PET54
- COX3 mRNA-specific translational activator PET494
- Cytochrome c oxidase subunit 3
- Protein PET111
- Mitochondrial COX1 translation regulator PET309
- Small ribosomal subunit protein mS26
- Mitochondrial inner membrane protein OXA1
- Small ribosomal subunit protein bS6m
Sequence:
MLTITKRLVTTDVRSRILLSSLNGKMSDALALLRQQQQTSVDVELLHTMLARAAALAHADTIAYMWYQHVMPRRLPVEGRLLCEMAGVALYQDRLFLPAQFLQHYQAMNRDRRTSPEDELIEYELRRIKVEAFARGTMHSTALREKWKVFLQEMDTLPGQPPLRLRDFPQMTKAMGIALMQQDEQAAALALFGRQPLVIKNEWSLPLLLAGVLWHVPGPAQARRVLAEFRQSYRGLPLLDAELVIKRRGFEINT
Protein: 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (F4IXL8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSYQTQINKFSQMALSVFAFPSYINRNPSLKYLKPSSMSSTKYSKVRATTFSEKGEYYSNRPPTPLLDTINHPMHMKNLSIKELKVLSDELRSDVIFNVSKTGGHLGSNLGVVELTVALHYIFNTPHDKILWDVGHQSYPHKILTGRRGKMKTIRQTNGLSGYTKRRESEHDSFGTGHSSTTLSAGLGMAVGRDLKGMNNSVVSVIGDGAMTAGQAYEAMNNAGYLHSNMIVILNDNKQVSLPTANLDGPTQPVGALSCALSRLQSNCGMIRETSSTLFEELGFHYVGPVDGHNIDDLVSILETLKSTKTIGPVLIHVVTEKGRGYPYAERADDKYHGVLKFDPETGKQFKNISKTQSYTSCFVEALIAEAEADKDIVAIHAAMGGGTMLNLFESRFPTRCFDVGIAEQHAVTFAAGLACEGLKPFCTIYSSFMQRAYDQVVHDVDLQKLPVRFAIDRAGLMGADGPTHCGAFDVTFMACLPNMIVMAPSDEAELFNMVATAAAIDDRPSCFRYHRGNGIGVSLPPGNKGVPLQIGRGRILRDGERVALLGYGSAVQRCLEAASMLSERGLKITVADARFCKPLDVALIRSLAKSHEVLITVEEGSIGGFGSHVVQFLALDGLLDGKLKVYRTWITNGSTS
Protein: Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A) (Q6TLE6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q96D31}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96D31}.
Interaction partners:
- Stromal interaction molecule 1 isoform X1
- Stromal interaction molecule 1a
- Stromal interaction molecule 2
- Stromal interaction molecule 2 isoform X1
- ORAI calcium release-activated calcium modulator 2
- Calcium release-activated calcium channel protein 1
- Transient receptor potential cation channel, subfamily C, member 1
- MORN repeat-containing 3.
- Calcium-transporting ATPase
Sequence:
MKMSRSEHSLQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDTNHDYPPGLLIAFSACTTVLVAVHLFALMVSTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAGVVLLCWVKFLPIKPKGQKNGTVSAGVAAAITSTSIMVPFGLVFIVFAVHFYRSLVSHKTDRQFQELEELEDLQNELDHREEVSTLQSPGSLYP
Protein: Ornithine aminotransferase (OTAse) (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase) (P07991)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the transamination of ornithine into L-glutamate gamma-semialdehyde, the second step of arginine degradation.
Subcellular location: Cytoplasm.
Interaction partners:
- Arginase
- Protein ARG5,6
- Glutamate 5-kinase
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
- Ornithine carbamoyltransferase
- Ornithine decarboxylase
- Gamma-glutamyl phosphate reductase
- Pyrroline-5-carboxylate reductase
- Uncharacterized protein YHR033W
- Argininosuccinate lyase
Sequence:
MSEATLSSKQTIEWENKYSAHNYHPLPVVFHKAKGAHVWDPEGKLYLDFLSAYSAVNQGHCHPHIIKALTEQAQTLTLSSRAFHNDVYAQFAKFVTEFFGFETVLPMNTGAEAVETALKLARRWGYMKKNIPQDKAIILGAEGNFHGRTFGAISLSTDYEDSKLHFGPFVPNVASGHSVHKIRYGHAEDFVPILESPEGKNVAAIILEPIQGEAGIVVPPADYFPKVSALCRKHNVLLIVDEIQTGIGRTGELLCYDHYKAEAKPDIVLLGKALSGGVLPVSCVLSSHDIMSCFTPGSHGSTFGGNPLASRVAIAALEVIRDEKLCQRAAQLGSSFIAQLKALQAKSNGIISEVRGMGLLTAIVIDPSKANGKTAWDLCLLMKDHGLLAKPTHDHIIRLAPPLVISEEDLQTGVETIAKCIDLL
Protein: Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog) (Q8VE96)
Organism: Mus musculus (Mouse)
Function: Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}. Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- FAS-associated factor 2
Sequence:
MAWTKYQLFLAGLMLVTGSINTLSAKWADNFVAEGCGGSQEHSFKHPFVQAVGMFLGEFSCLAAFYLLKCQGRRQSASSVEPQQPFNTLLFLPPALCDMTGTSIMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLDRRLAPSQWLGILITIAGLVVVGLADLLSKHDSQHKLSEVITGDLLIIMAQIIIAIQMVLEEKFVYKHNIHPLQAVGIEGFFGFVILSLLLVPMFYIPTASFSGNPRGVLEDALDAFCQVGRQPLIALALLGNISSIAFFNFSGISVTKELSATTRMVLDTLRTIVIWAFTLALGWEIFYPLQILGFLILLMGTALYNGLHRPLLAFLSRRWRLPTQEGEQERLLGDSRTPINEAS