wanglab/gogpt-training-data huggingface dataset:
Protein: Transcriptional coregulator psa-3 (Phasmid socket absent protein 3) (Q0G825)
Organism: Caenorhabditis elegans
Function: Probable transcription coregulator. Required for asymmetric cell divisions of the T hypodermal cells, and cell fate determination, in concert with homeobox proteins nob-1 and ceh-20. Acts downstream of the Wnt signaling pathway, and of ceh-20 and nob-1.
Subcellular location: Nucleus {ECO:0000305|PubMed:16824957}.
Interaction partners:
- Homeobox protein ceh-20
- Homeobox protein nob-1
- Homeobox protein ceh-10
- Homeobox protein ceh-22
- Prion-like-
- Proteasome activator complex subunit 3
- Homeobox protein ceh-40
- Paired domain-containing protein
Sequence:
MTSEPSTSSEAGSSSLLDADKTNLLQEALVRAGVIRSQRQGISPTATNIKSPKKSALFEKIASHPLMPIVELLLEKCETAATTFDRKAFETDDIKRLFQSLEQRGVQLSSNRDEVDELMETAILALRTCMVELERVYSLMESFKAKYLATLRRTVCHEALVGNNGDSDDELSDNPLMPVLEMSEAAFQAQNKAMESALATLQSVSGSLSLPLQFTHQSITAAQIERNLEFLKQCGFPTQLPPNFLKPSNEKSPEKSEEEKSQKPSSSPKSPSLSD
Protein: Keratin-associated protein 20-1 (Q3LI63)
Organism: Homo sapiens (Human)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Interaction partners:
- Keratin-associated protein 22-1
- Keratin-associated protein 15-1
- Keratin-associated protein 24-1
- Keratin-associated protein 6-3
- Small cysteine and glycine repeat-containing protein 1
- Keratin-associated protein 26-1
- Keratin-associated protein 6-1
- Keratin-associated protein 13-3
- Keratin-associated protein 7-1
- Keratin-associated protein 27-1
Sequence:
MIYYSNYYGGYGYGGLGCGYGCGYRGYGCGYGGYGGYGNGYYCPSCYGRYWSYGFY
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q8H935)
Organism: Vicia faba (Broad bean) (Faba vulgaris)
Interaction partners:
Sequence:
MEPFTRDHRGSLEVFNPSSSETNGTPNPNPNPNPSNSWNTGTSSRGTEAPPLRDSIISDEVPTATSWMALKETTPSPKSGESGSVAEQRAAEWGLVLKTDSETGKPQGVGVRGSGGGGGSRRDSNNSVRSSGESSDDGREGGRGIPRVSEDLRDALSAFQQTFVVSDATKPDYPIMYASAGFFSMTGYTSKEVIGRNCRFMQGADTDPNDVAKIREALAAGTSYCGRLLNYKKDGTTFWNLLTIAPIKDEHGKILKLIGMQVEVSKHTEGTKEKMLRPNGLPESLIRYDARQKEKANSSVTELVEAVSKRPRSLSESANRLPFNKKPTNGSNDHATPPNSESSSRKSGSTLRSFRRKSHSGAGNSNSMHPITELPENNNKSRRRSFMGFMRKSLSNNERFNHEQVIDRNSSEDEDRLDSFDEQNIAQKREKRKGFDLATTLERIEKNFVITDPRLPDNPIIFASDSFLELTEYSREEILGRNCRFLQGPETDPATVKKIRYAIDNQTEVTVQLINYTKTGKKFWNLFHLQPMRDQKGEVQYFIGVQLDGSQHVEPLHNGIAEDTAKEGENLVKKTAENVDDALRELPDANMKPEDLWMNHSKVVHPKPHRREDSAWRAIQKIMESGEQIGLKHFKPIKPLGSGDTGSVHLVELCGTDHHFAMKAMDKGVMPNRNKVHRACTEREILDMLDHPFLPALYASFQTKTHICLITDYCPGGELFMLLDRQPAKVLKEDAVRFYATEVVVALEYLHCQGIIYRDLKPENVLLQSTGHVSLTDFDLSCLTSCKPELIVPSTNDKKKGQHGPIFMAEPMRASNSFVGTEEYIAPEIITGSGHTCAVDWWALGILLYEMFYGYTPFRGKNRQRTFANILHKDLKLPKSKQVSLSAKQLIYHLLQRDPTSRLGSKGGANDIKHHSFFKGINWALVRCTKPPELDAPLFDTNKEEKEKDDKYVDNGQEDMSVF
Protein: Arogenate dehydratase (EC 4.2.1.91) (Q6Z3Y3)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast stroma {ECO:0000256|ARBA:ARBA00004470, ECO:0000256|RuleBase:RU363004}.
Interaction partners:
- chorismate mutase
- Chorismate mutase
- Chorismate mutase
- Chorismate mutase
- histidinol-phosphate transaminase
- Os06g0709000 protein
- Os06g0542200 protein
- Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase
- nicotianamine aminotransferase
- Os11g0552000 protein
Sequence:
MVSPSLRIPAAARVFDPAINTRCPPPHAVVMRMRSRSRRSIAASASPPGDPSIRDPISLPRPLTSADLMEASGDGLKVAYQGCPGAYSEAAAKKAYPSCHTVPCEYFETAFQAVENWVADRAVLPLENSLGGSIHRNYDLLLRHRLHIVGEVRLAVRHCLLANRGVKIQNLRSAMSHPQALAQCEQTLTKLGIEHREAVDDTAGAAKLIAEQKLQDTGAVASSLAAQLYGLDILAENIQDDTDNVTRFMMLAREPIIPRTDKPFKTSIVFSLEEGPGQLFKALAVFALRKINLTKMESRPHKKKPLRIADDNCSAPLKHFDYLFYVDLEASMADPNAQNALANLKEFATFLRVLGSYPTDVSEA
Protein: Protein DETOXIFICATION 29 (AtDTX29) (Multidrug and toxic compound extrusion protein 29) (MATE protein 29) (Q38956)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:17151019, ECO:0000269|PubMed:23903016}; Multi-pass membrane protein {ECO:0000255, ECO:0000269|PubMed:23903016}.
Interaction partners:
- Probable acyl-activating enzyme 5, peroxisomal
- non-specific serine/threonine protein kinase
- Probable E3 ubiquitin protein ligase DRIPH
- Transcription factor MYB3R-2
- Phospholipid-transporting ATPase 6
- Beta-galactosidase 12
Sequence:
MAKDKDITETLLTAAEERSDLPFLSVDDIPPITTVGGFVREFNVETKKLWYLAGPAIFTSVNQYSLGAITQVFAGHISTIALAAVSVENSVVAGFSFGIMLGMGSALETLCGQAFGAGKLSMLGVYLQRSWVILNVTALILSLLYIFAAPILASIGQTAAISSAAGIFSIYMIPQIFAYAINFPTAKFLQSQSKIMVMAVISAVALVIHVPLTWFVIVKLQWGMPGLAVVLNASWCFIDMAQLVYIFSGTCGEAWSGFSWEAFHNLWSFVRLSLASAVMLCLEVWYFMAIILFAGYLKNAEISVAALSICMNILGWTAMIAIGMNTAVSVRVSNELGANHPRTAKFSLLVAVITSTLIGFIVSMILLIFRDQYPSLFVKDEKVIILVKELTPILALSIVINNVQPVLSGVAVGAGWQAVVAYVNIACYYVFGIPFGLLLGYKLNYGVMGIWCGMLTGTVVQTIVLTWMICKTNWDTEASMAEDRIREWGGEVSEIKQLIN
Protein: Large ribosomal subunit protein eL28 (60S ribosomal protein L28) (F1QFV6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MASPHLQWMVIRNSSSFLIKRNKQTYSTEPNNLKARNAFRFNGLIHRKTIGIEPAADGKGVVVVLKKRSGQRKPASSYGKITINKNSRATLASVRNIIRKNKYRRDLRMAALRRVSAILSSQKPVVVRKKRSRAPKSS
Protein: Insulin gene enhancer protein isl-2a (Islet-2A) (Insulin gene enhancer protein isl-2) (Islet-2) (P53406)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Binds to one of the cis-acting domain of the insulin gene enhancer. May be involved in subtype specialization of primary motoneurons.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein HB9
- LIM/homeobox protein Lhx3
Sequence:
MVDILPHPSFLGDMGDHSKKKSGIAMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDEELLCRADHGLLMERASAGSPISPGNIHSSRPLHIPEPVPVRQPPHRNHVHKQSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHNDKTNLQGLTGTPLVAGSPIRHDTTVQGNPVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET
Protein: Tetratricopeptide repeat protein 36 (TPR repeat protein 36) (Q8VBW8)
Organism: Mus musculus (Mouse)
Interaction partners:
- 4-hydroxyphenylpyruvate dioxygenase
Sequence:
MGTPNDQAVLQAIFNPDTPFGDVVGLDLEEAEEGDEDGVFPQAQLEHSKALELQGVRAAEAGDLHTALEKFGQAISLLPDRASAYNNRAQARRLQGDVAGALEDLERAVTLSGGRGRAARQSFVQSGLLARFQGRDDDARRDFEKAARLGSPFARRQLVLLNPYAALCNRMLADMMGQLRAPSNGR
Protein: Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1) (P14094)
Organism: Mus musculus (Mouse)
Function: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Subcellular location: Cell membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:P07340}; Single-pass type II membrane protein {ECO:0000255}. Cell membrane, sarcolemma {ECO:0000269|PubMed:23392350}. Note=Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes. Localizes in long striations at the level of Z and M lines. {ECO:0000269|PubMed:23392350}.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit gamma
- Sodium/potassium-transporting ATPase subunit alpha-1
- Sodium/potassium-transporting ATPase subunit alpha-2
- Sodium/potassium-transporting ATPase subunit alpha-3
- Potassium-transporting ATPase alpha chain 2
- Sodium/potassium-transporting ATPase subunit alpha-4
- Sodium/potassium-transporting ATPase subunit beta-2
- Sodium/potassium-transporting ATPase subunit beta-3
- Phospholemman
- cAMP-dependent protein kinase catalytic subunit beta
Sequence:
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISELKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIIRFLEKYKDSAQKDDMIFEDCGNVPSEPKERGDINHERGERKVCRFKLDWLGNCSGLNDDSYGYREGKPCIIIKLNRVLGFKPKPPKNESLETYPLMMKYNPNVLPVQCTGKRDEDKDKVGNIEYFGMGGYYGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTVDTEIRVECKAYGENIGYSEKDRFQGRFDVKIEIKS
Protein: GH01875p (Q9V9N7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVTICSLSAALSCNIAYRFPIYEMEHLDLAGYLGHTPQSWNTLGTFQDQDAVYLSSSRQMLEPILEETSEDEERARSSLIVSLDRRSTLWSSTESETGSVLRIETIKDIDAVSERDFVCPPKRPRRSHDLNSGQISEDCVQLRRPMPYDPEYHNSFERFLALEACARDSFGSQGQRSSIGSRRGGTFEDFYSDRDSSHSLSRSSSLVQFESLERQLTLQEQHQSMNSLGNSSPSLTCESGASTRARTRDSSPESRKGSAPTLSLLKRYESSDCSHLHQTYYELNNLNFEYKQQQELLSRSLREAELKSDLESSSSSSSSSDSSGHSLLSSCLVPGDAVATERGKQDGTNSRRIPPNSAENLSEDSGYCEPRTLKREKSKSIPKNFEKLCEEEEELLLLEEGAPHSRDFKDEHDLCQTEIEQTADTAALACSPSSINSSPERASSESESASPLPSPTGSASTSSAASFTWLHNSLPDIREPRGPLSVEINNSKPKTNGSVLATTRQNSGSTRSSSSADSCDGISLLGPTHSLNELQVLERRRRPRHIRPSQRNCHSNSSSEELEELDNLFVACHTPPRIRRSCSWNERARKVVGVASAGYLNASYQNLTLLNYTDNWLPAEILQKNHKRSPAEEMSKQSSNTCGNYEHMICKGNFLLDEISKVYDKNVSILTDKPVLDTKLPAPVECDLNEPIECSKVQHVQLNIKPPPRQKRLTQQPPAAMTFNGLVKTFDQDPTNLRTSYTQSLEQCHLDEQETAKPASYPPSAISQRFLPKRRFQSQTSAAKQRSLVSSTPNLAASDDGQPESEYDIYVSSAHASMHQLPQTTTLPKPLGILLPAGSRHSFGKEVSFCPVVSKYCWQEQSSEEPTEDQFHSSEGEQGPPSDDELMDPTLVHNTRENENIAALFEPEPEQAHRLREPAIAQKFTGFHTNALLSASTHAEKNLSCEESANVKNKANLATPDCRDQRTEAKTTLEPEPALSSTVSLKPCAVANSSCREETPSDAINEPASATARPLSLPILSEPPTNRAHRILYSSQQLRRYEPKASPINKMPPANELSPQAAAVARTDEKHPTSRSLFSRFTHGLRFSLRRKKKQQQQEPSQVKESPKELRQSPEESQPVDFVHIPLKPPRSSQCGRLDDTIVSETSSGHVHSWQQQEQLGKTSTLQKVTGKPPLPKMPPRSGILTHAPQETTGETVNCHRTEALPSVEREHCNQLTGQLVAKVQAQRMRDTGLSSQIVVAEETHTVNRLAGHGDATRPTVVTAVPVSVAPVAEVDKMGLIETNLDTHETVISGKTRSLMDITCNPLSMPHKRYIVKRLNVNSVAYDVDELDAEVKPSPGGMASVRRPHKSMEFLLDKENQKNILPPENELQKSHDHNPGALSEHQLRVQASLQRLNIPDWFRHYNKGPEKAADGENACTSATGGGYRPGNFTRKRAQESGRWQGLNSKTTSLSSLGSQRSDRSPLLMSPSAHSHHGGQSSYSCGSTTIHGPAPVQIGMGATRWSTSHLNSTQMSPGASQRGSFTRGAPINSSFISVASGSGLLRNSYRQPYLGWRSTEKLSQRTPHERLANSLLTQRTAPPSTRAGNETRTLHSVSTEIQSSIKEVTSAIVHFVNDQQQSQHPRSRSTSPNSRCWLESSFVGTRTLDSPQTPVIDNSPPELARKQQQLHPHQVHLDVGLSPVVSAGQLPHRMNGINRIGNGGGESAIQV
Protein: Uncharacterized protein C29E6.07 (Q09861)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MEYYIRETLITDFQDVKTLKNKRKCFSFFFELRLFSPQCLFIVYFFYLLHVRINTSPLFIKTTTRPTALIHITKYSEALASRLLKGHMTQLSLRTILPPAHTKNLHRQQPTTWLDS
Protein: Heat shock 90kDa protein 1 beta isoform b (Q5DW65)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MPEEMRQEEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPTKLDNGKELKIDIIPNVEERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVTVITKHNDDEQYIWESSAGGSFTVKVDSGEPMLRGTKVILHMKEDQTEYVEEKRVKEVVKKHSQFIGYPITLFVEKEREKEISDDEAEEEKEEKAAEKAEAEDKPKIEDVGSDDEEDSKDKDKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITMEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCEELIPEYLNFVRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCMELFGELAEDKENYKKFYDGFSKNLKLGIHEDSQNRKKLSELLRYHSSQSGDELTSLTEYLTRMKDNQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKMDEDKTKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKADLDKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDEVIPEETTSAPAPDEIPPLEGDEDASRMEEVD
Protein: Antigen peptide transporter 1 (APT1) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1) (Peptide transporter TAP1) (P21958)
Organism: Mus musculus (Mouse)
Function: ABC transporter associated with antigen processing. In complex with TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules. Uses the chemical energy of ATP to export peptides against the concentration gradient. During the transport cycle alternates between 'inward-facing' state with peptide binding site facing the cytosol to 'outward-facing' state with peptide binding site facing the ER lumen. Peptide antigen binding to ATP-loaded TAP1-TAP2 induces a switch to hydrolysis-competent 'outward-facing' conformation ready for peptide loading onto nascent MHCI molecules. Subsequently ATP hydrolysis resets the transporter to the 'inward facing' state for a new cycle. As a component of the peptide loading complex (PLC), acts as a molecular scaffold essential for peptide-MHCI assembly and antigen presentation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q03518}; Multi-pass membrane protein {ECO:0000255}. Note=The transmembrane segments seem to form a pore in the membrane.
Interaction partners:
- Antigen peptide transporter 2
- Tapasin
- Calreticulin
- Calreticulin
- Protein disulfide-isomerase A3
- Proteasome subunit beta type-9
- Beta-2-microglobulin
- Proteasome subunit beta type-8
- H-2 class I histocompatibility antigen, K-B alpha chain
- H-2 class I histocompatibility antigen, D-B alpha chain
Sequence:
MAAHVWLAAALLLLVDWLLLRPMLPGIFSLLVPEVPLLRVWVVGLSRWAILGLGVRGVLGVTAGAHGWLAALQPLVAALSLALPGLALFRELAAWGTLREGDSAGLLYWNSRPDAFAISYVAALPAAALWHKLGSLWAPSGNRDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAIPFFTGRITDWILQDKTVPSFTRNIWLMSILTIASTALEFASDGIYNITMGHMHGRVHREVFRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISGTLSLLLWYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEALAYVAEVWTTSVSGMLLKVGILYLGGQLVIRGAVSSGNLVSFVLYQLQFTQAVQVLLSLYPSMQKAVGSSEKIFEYLDRTPCSPLSGSLAPSNMKGLVEFQDVSFAYPNQPKVQVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGQCLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDFISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQLSLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEALAAPAD
Protein: Uncharacterized oxidoreductase SPAC977.08 (EC 1.-.-.-) (P0CU00)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Acireductone dioxygenase-requiring))
Sequence:
MREPKNAKVLSRLENVLVTQLDVNNFSSIKKSVEKAISHFGRIDVLLNNAGYSVYSPLESTTEEQIHNIFNTNVFGALEVIKAITPIFRSQHNGMIINVSSIGGKMTFPLGCLYYGTKYAIEGISEALTWEMQSIGVKVKIIEPGFTATEFRVEEGAGKHYAEYDNLKQKLYEDLLPKLKTATPPQKIAEVILQAATDESDELRYPTGDYVVEWMALRSKVDDATFLATHRKQMGL
Protein: Transposon Ty1-NL2 Gag-Pol polyprotein (Gag-Pol-p199) (TY1A-TY1B) (Transposon Ty1 TYA-TYB polyprotein) (p190) [Cleaved into: Capsid protein (CA) (Gag-p45) (p54); Ty1 protease (PR) (EC 3.4.23.-) (Pol-p20) (p23); Integrase (IN) (Pol-p71) (p84) (p90); Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (Pol-p63) (p60)] (Q99337)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
Subcellular location: Cytoplasm. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSDWSFYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISKSDILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHTSKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTKLSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIEQCDMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVHLNPKGKKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
Protein: Uridine phosphorylase (EC 2.4.2.3) (F7F0D5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAATGTEAKDLENHHNDCLVQLSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMSAFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVTRNTSLDAQLVQELMQCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHNVLVEYQQRPQRLVGHFIKKRLGRA
Protein: Brevinin-1CDYa (B3VZU0)
Organism: Rana dybowskii (Dybovsky's frog) (Korean brown frog)
Function: Antimicrobial peptide. Has low activity against the Gram-positive bacterium S.aureus (MIC=12.5 uM) and the Gram-negative bacterium E.coli (MIC=25 uM). Has weak hemolytic activity against human erythrocytes.
Subcellular location: Secreted {ECO:0000269|PubMed:19539775}.
Interaction partners:
Sequence:
MFTLKKSLLLIFFLGTINLSLCEEERNADEEERRDDLEERDVEVEKRLLSLALAALPKLFCLIFKKC
Protein: Small ribosomal subunit protein mS22 (28S ribosomal protein S22, mitochondrial) (MRP-S22) (S22mt) (P82649)
Organism: Bos taurus (Bovine)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:10938081, ECO:0000269|PubMed:24799711}.
Interaction partners:
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein mS40
- Small ribosomal subunit protein mS34
- Small ribosomal subunit protein mS31
- Small ribosomal subunit protein mS25
- Small ribosomal subunit protein mS39
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein mS35
Sequence:
MATLRVSLSLWNLHAGSRGAGRVYFRARARPRPGDLFQPLPGVCGAGTPCRGLCSEAESGSPKIKKPTFMDEEVQSILIKMTGLDLLKIFKPAVQETKPPTYKLMTQAQLEEATRQAIEAAKVRLKMPPVLEERTPINDVLAEDKILEGTETGKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQIYFPKEGRRVLTPVIFREENLQTMYSQDRHVDVLNLCVAQFEPDSADYIKVHHQTYEDIDKYGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDAASLVQLYHILHPDGQSAQEAKEQAAEGLQLIKVFAKTEAQKGAYIELTLQAYQEAFISSSAAS
Protein: Acylcarnitine hydrolase (ACH M1) (EC 3.1.1.28) (Carboxylic ester hydrolase) (EC 3.1.1.-) (O70631)
Organism: Rattus norvegicus (Rat)
Function: Hydrolase with high activity towards palmitoylcarnitine. Is also active with p-nitrophenylacetate and alpha-naphthylacetate (By similarity). May also hydrolyze retinyl esters.
Subcellular location: Microsome {ECO:0000269|PubMed:12230550}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q91WG0}.
Interaction partners:
Sequence:
MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL
Protein: Probable oxidoreductase (Q11061)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized FAD-linked oxidoreductase Rv2280
- Malate synthase G
- Multidrug efflux pump Tap
- Isocitrate lyase
- Putative isocitrate lyase subunit B
- Putative isocitrate lyase subunit A
- GTPase HflX
- Alanine aminotransferase
- D-amino-acid oxidase
- Cytochrome P450 130
Sequence:
MNTDVLAGLMAELPEGMVVTDPAVTDGYRQDRAFDPSAGKPLAIIRPRRTEEVQTVLRWASANQVPVVTRGAGSGLSGGATALDGGIVLSTEKMRDITVDPVTRTAVCQPGLYNAEVKEAAAEHGLWYPPDPSSFEICSIGGNIATNAGGLCCVKYGVTGDYVLGMQVVLANGTAVRLGGPRLKDVAGLSLTKLFVGSEGTLGVITEVTLRLLPAQNASSIVVASFGSVQAAVDAVLGVTGRLRPAMLEFMDSVAINAVEDTLRMDLDRDAAAMLVAGSDERGRAATEDAAVMAAVFAENGAIDVFSTDDPDEGEAFIAARRFAIPAVESKGALLLEDVGVPLPALGELVTGIARIAEERNLMISVIAHAGDGNTHPLLVYDPADAAMLERAHLAYGEIMDLAVGLGGTITGEHGVGRLKRPWLAGYLGPDVLALNQRIKQALDPQGILNPGSAI
Protein: Beta-amyrin synthase (EC 5.4.99.39) (Q8W3Z1)
Organism: Betula platyphylla (Asian white birch)
Function: Oxidosqualene cyclase converting oxidosqualene into beta-amyrin, generating five rings and eight asymmetric centers in a single transformation.
Interaction partners:
Sequence:
MWRLKIADGGSDPYIYSTNNFVGRQTWEFDPQAGSPQERAEVEEARRNFYDNRYQVKPSGDLLWRMQFLKEKNFKQTIPPVKVEDGEEITYEKSTAALRRAVHFYSALQASDGHWPAENAGPLFFLPPLVMCMYITGHLNTVFPAEHQKEILRYIYYHQNEDGGWGLHIEGHSTMFCTALSYICMRILGEGPDGGQDNACARARKWILDHGGVTHMPSWGKTWLSILGIFEWIGSNPMPPEFWILPSFLPMHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYTQPYHQVNWKKVRHLCAKEDIYYPHPLIQDLLWDSLYIFTEPLLTRWPFNKLVREKALQVTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHIARIPDYIWVAEDGIKMQSFGSQEWDTGFAIQALLASNLTDEIGPTLARGHDFIKKSQVKDNPSGDFESMHRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLFSIMPPEIVGEKMEPEQLYDSVNVLLSLQSKNGGLAAWEPAGAQEWLELLNSTEFFADIVIEHEYIECTASAMQTLVLFKKLYPGHRKKEIENFIKNAAQFLQVIQMPDGSWYGNWGVCFTYGTWFALGGLAAVGKTYNNCLAVRRAVDFLLRAQRDNGGWGESYLSCPKKEYVPLEGNKSNLVHTAWAMMGLIHAGQAERDPTPLHRAAKLIINSQLEDGDFPQQEITGVFMKNCMLHYAAYKNIYPLWALAEYRKHVPLPLGKNLNQVVNCIGQSLYKKYK
Protein: Src kinase-associated phosphoprotein 2 (Pyk2/RAFTK-associated protein) (SKAP55 homolog) (SKAP-HOM) (Src family-associated phosphoprotein 2) (Src kinase-associated phosphoprotein 55-related protein) (Src-associated adapter protein with PH and SH3 domains) (Q3UND0)
Organism: Mus musculus (Mouse)
Function: May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11063873, ECO:0000269|PubMed:12893833, ECO:0000269|PubMed:19026786}. Note=Membrane ruffles of macrophages. Perikarya and dendrites from neurons.
Interaction partners:
- Integrin beta-1
- FYN-binding protein 1
- Integrin alpha-4
- Integrin alpha-5
- Lymphocyte cytosolic protein 2
- PML-RARA-regulated adapter molecule 1
Sequence:
MPNPSCTSSPGPLPEEIRNLLADVETFVADTLKGENLSKKAKEKRESLIKKIKDVKSVYLQEFQDKGDAEDGDEYDDPFAGPADTISLASERYDKDDDGPSDGNQFPPIAAQDLPFVIKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYDVRMNNTLRKDGKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDLGSDVIPEDDEERGELYDDVDHPAAVSSPQRSQPIDDEIYEELPEEEEDTASVKMDEQGKGSRDSVHHTSGDKSTDYANFYQGLWDCTGALSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYLMEMYDI