wanglab/gogpt-training-data huggingface dataset:
Protein: Ca(2+)/calmodulin-responsive adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Protein rutabaga) (P32870)
Organism: Drosophila melanogaster (Fruit fly)
Function: This is a membrane-bound, calmodulin-sensitive adenylyl cyclase. Inactivation of this cyclase leads to a learning and memory defect.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- 3',5'-cyclic-AMP phosphodiesterase, isoform I
- LD28489p
- RAC serine/threonine-protein kinase
- IP06402p
- Bis
- Inosine triphosphate pyrophosphatase
- Amnesiac neuropeptides
- Molybdenum cofactor biosynthesis protein 1
- GTP cyclohydrolase 1
- Neuropeptide F
Sequence:
MDHAVKATRGRPLNTLRFENDELECLYQRYTLKLQRFSVLGVVALVFVLCGVMAALSLTFNNAATFHNIFNAIVCGLFAVVLVLLQCSVIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYKIFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDILSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVPPPHRRKPLMLNTLGVRSAIGSRRKLSFRNVSNVVMQLLHTIKFSEPVPFSNIATGSFPSAASALGGGVSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGGGVDSGISGGGGCVSGGIAGGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRKRHSVAAHHQPTNRVNRFLSQAINARSVDCDKSEHVDRLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGNGTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLVGSHFEFRCRGTIKVKGKGDMVTYFLCDSGNKSLNGEVRNAMSLPQSLHAPDYYMKVSQFPENRVNTDTYSKKENGHLYAGNGVEEQQLLLQHQHKQHDPLPLPAPPPPVHHHLHQQQQQRLNSKLQKQPIFMANGGLPNIRENGNGHNGEHQQQQQQQQQHQQQQQQQQQHGGFMVATTTPPAAVAVPLQPQHHQLQFQHPHQHPLPSAVSVPVQHQILLHHQLQLQHQPVPSVMLREFNIIENPTSGGRHQQMEQLPPHHGSLDLSGMGMGVGAGVLGSDCFMMPRRDRERTYVPPLNQHGHHPPHHLHSNLNLNQSQHPPSFTSLGYGQCRESEPLLHASSVAPVAKIMPMQHAPKYEPPRYTSPHTMLSQQHQQQQQQQHQHQQPQSQSAQDQQTHPAQDPHPLQRQYAMYSQQPQLPPKPVLRTYMKPLPKLPTDLEESRDMSSTDDLSSRPHSPSMSSSDESYSKTTEGEGEGDEDSPRMVNGGHLHHRNGYHLPAGGLVNPLQWLYPCDIQVDPTSPVVDMAHLHDFELSSTTESQGHHTNSNTTSNTQHKGDSCNSFDFQKAAVGTAAGAAIATKSPFERELQRLLNESSRARCLATATTTAGAISTTDQTASNGSRELSYSLSNGKLSSANGHGVGGSGSGSGSGSGSGSAVGNGSGGSGSSNGNLSGGSGSNSNSGNNNSSHHKTEQQQNMDHEHLAGGKLLGSNSFMIAKHPVGLEAIKEITRNKNPSESSQMQTSDTESCEILHENRNQMHVLAMLEMHTAKELNGSHAHHGQHHQQPQRTHRQRPRSKELQYSHESLDGLDGAVQSQSQQRHQRYHHHHHHQQRQQQQQRYNHVQEQEERDDTEDNLADEEFEDDEVGRDVRQKRLQKSELNHKRSEVATEAGNHHDDEVEEEDDDDDEEEDHRNGGREAAPLTNGSMRGLEANVINDELKYGATHLNHQSMDSNPLESQSEWSDDDCREEATGGAESTGYITDEPGLENISLLNEAGLTDAEGALSDVNSLYNAPDVDDTSVSSRASSRLLSLDSLSGLYDCDLDSKHELAIVNASHKISSKFGQPLSPAQQQHQQQQQQQQQQQQQHHQQQLQQNPQHTQAQSHLAPVQFQSAEELRE
Protein: Wide awake, isoform D (Wide awake, isoform E) (A0A0B4K6D0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNRCYHSDSTKLPNMPQKLPMSSCLRSPAVFVRQKSFHTLNELTRFCQLKVSPHRSTATATSTSSSPSSSPAAAQQQRRHSHYAIDDNILPQDKRDGDIDSVRLREKVVNPSGGNNNNQDNYPTYYPAPLLSTSRWSEQLTQHAAVAKIRTAISCHSQDLREMEFLLPHSRTDSQSNSQSQLCISRHSQPKNAKLRDDHDETGSSELDSPPLGDENASANGQLSVHRQPVQLRSKIPGNTPHPRASKMSKKQLKLAQAQLDKLTQNNLHLHALFSAVEHGHLEKARTILESTDVDVNSINNDGLSALDLAVLSNNRSMTRMLLQHGAVEGSQFSVDTIGTKLNGLLKDAESRIHDLSGPEGLCPPVFASRPSISSIIIGNSSASVTGCTGSEVEKQIGIWERRVKGLRRLQLGWDQARPPDAPASVVVDVTGDNSISVQILEPFEGAIGTKFKVQWSTRADFNNVVGESELLEWISFHGTMGAQCHISGLTQGRRYFLRAACGNVKGWGTYRTSVPASVVPSTWRDLDNREDRFVGRHRILDNLFTAVRLARPADVSELTLDPASAQRRNPKKKTTIKQLFSVTTKFQKTLRRGIYFSCIIHCDDKVLVTSEDFPPVIEVDESYPSALHMDYYWLMKVACTWEDVKSLRSDMERNLTSAVHFRTKLLSAVCQMQSALGITDLGQLYYKPLRDAQGTVVLTCVQSVKSQKAVSILNSRWVPVSKLQKKLGALHEDYTINELLISSIGDQLHYQQAALQRLEPGLYLGYLKMQCSIDQIQVVVPVKTPNVLPHCKVRENSHITAEEWQVLHRYSSDPLRLPLDFSAQGGDGASGATATTEVQRLFLYDLTNAMHKLFASMNIKIADATTHRLYDVEVIEHSPDISFLVVCPSAESSCAVPGQSELLLQRDDLASLSIQAFEMIHLRTYQPAIIQKYARLSCILELDTALATHSLREAFSSSELQAAKERLATLQELSASLTIVWKSVRWLMDVVAYARNKNAQPSLAMREILDFAQQRQDEAVATSAGGSANKQLLQLPIRESKFSKTGQGRGSWPGPGTSEDQSQNKPEHSKSEQNLELSAITPVEPASNQVPTQQQQPQQQSQQQQLLQVSNISEYAGSICSEVSFRKNSGDSMSSTYTSRSFYSAVDSASDGNSTNSVFAIPPSRSDDTLADALRHSQAVAAQRKRTSSNIASHTNPLITVHSSSSAPYLAGSSVSLRSGNGAFATDLEHKPLKPATKAASSANLREGGPYLKSTLAELRAVGGEEPVASTSKASSMKSLSRQSSEEDSASCSSLNAEQTSGIIQVYTAYSTGLASGTSLKIHVTPKTTAREVINLVVKQLNMAVVLKGNNGPIYGPEMLENFCLVAVIGARERCLRDDFKPLQLQNPWKKGRLYVRKKHELLAAIEHSNRKSHLI
Protein: mitogen-activated protein kinase kinase (EC 2.7.12.2) (K7EIW3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSHRAWAEGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDV
Protein: Variant surface glycoprotein (VSG), putative (Q22KT8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MTESSQQRRSTFNRYIAAAVAILLPILPQQAIQQLPPAVLADVNTVCREATYFTVASNQYVQKLQQLSSDLTSSQIQTKVWQLAAAKAAAVDKKAFYTSLIAYDNKRRREAAITATAAIQAVTRALAAVARQAGYLNGREHAADLLAGAALAGDPTHSGTRCTHAITQTPTTFSTCTDGSLEAAGFTNTDLDIFRTTHVKISKHSDLKTLTSTSNVIATTTGTTFTGASAGKCQDSSESGITDVQLSLKLTKEASLSTAASKLKNHGTARDSCRQKPEQQQVEANEDKLERLICEAQQAVAKAKLDITGLDVAALQADEVMLEATNNLAMGNERVGDPTKREGKEAVAKKIAALAGDPTNFYATFVSELNKQKVTFKKAGKTTEKSLEDIAKSDDFGIAVSYFEGQSMLAIADAATKTCKPQLTETEATCAARGAGDDCKSPCKLVEEEGGKKKCTLDAKAAKKQAQNQETEDKDDKTTSTTGSNSFLITKAPLLLAYLIL
Protein: Pre-mRNA-processing factor 19 (EC 2.3.2.27) (PRP19/PSO4 homolog) (RING-type E3 ubiquitin transferase PRP19) (Q10051)
Organism: Caenorhabditis elegans
Function: Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Core component of the NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity (By similarity). Together with emb-4, necessary for interaction of rnp-4, a probable exon junction complex component, with mRNAs and spliceosomal snRNAs. Plays a role in nuclear retention of unspliced mRNAs.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9UMS4}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9UMS4}.
Interaction partners:
- Pleiotropic regulator 1
- Cell division cycle 5-like protein
- Intron-binding protein aquarius
- Pre-mRNA-splicing factor SYF1
- TPR_REGION domain-containing protein
- Peptidyl-prolyl cis-trans isomerase E
- Protein isy-1
- Spliceosome-associated protein CWC15 homolog
- Pre-mRNA-splicing factor syf-2
- Pre-mRNA-splicing factor 8 homolog
Sequence:
MSFVCGISGELTEDPVVSQVSGHIFDRRLIVKFIAENGTDPISHGELSEDQLVSLKSGGTGSAPRNVSGTSIPSLLKMLQDEWDTVMLNSFSLRQQLQIARQELSHSLYQHDAACRVISRLSKELTAAREALSTLKPHTSAKVDDDVSIDESEDQQGLSEAILAKLEEKSKSLTAERKQRGKNLPEGLAKTEELAELKQTASHTGIHSTGTPGITALDIKGNLSLTGGIDKTVVLYDYEKEQVMQTFKGHNKKINAVVLHPDNITAISASADSHIRVWSATDSSSKAIIDVHQAPVTDISLNASGDYILSASDDSYWAFSDIRSGKSLCKVSVEPGSQIAVHSIEFHPDGLIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVRSIAFSENGYYLATGSEDGEVKLWDLRKLKNLKTFANEEKQPINSLSFDMTGTFLGIGGQKVQVLHVKSWSEVVSLSDHSGPVTGVRFGENARSLVTCSLDKSLRVFSF
Protein: GnIH (Neuropeptide VF precursor) (A0A0F7CWL3)
Organism: Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MEIISTQKFILLTLATVAFLTPHGACLDELMKSSLESREDDDDKYYEIKDSILEEKQRSLNFEEMKDWGSKNFMKVNTPTVNKVPNSVANLPLRFGRSNPEERSIKPSAYLPLRFGRAFGESLSRRAPNLSNRSGRSPLARSSIQSLLNLPQRFGKSVPISLSQGVQESEPGM
Protein: Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A) (Q5TA82)
Organism: Homo sapiens (Human)
Function: Precursors of the cornified envelope of the stratum corneum.
Interaction partners:
- Late cornified envelope protein 1A
- Late cornified envelope protein 6A
- Late cornified envelope protein 2C
- Late cornified envelope protein 2B
- Late cornified envelope protein 1D
- Late cornified envelope protein 1C
- Late cornified envelope protein 1F
- Late cornified envelope protein 3E
- Late cornified envelope protein 1B
- Late cornified envelope protein 3D
Sequence:
MSCQQNQQQCQPPPKCPPKCTPKCPPKCPPKCPPQCPAPCSPAVSSCCGPSSGSCCGPSSGGCCSSGGGGCCLSHHRPRLFHRRRHQSPDCCESEPSGASGCCHSSGGCC
Protein: Cep192 protein (Q7TMP0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
QFLTWGGIPLGRTQLQKLALRNSSTTTAQNLRLFIKGQDQDCFQIQNTFGSEERLTSNCEIRICPGEDFVISVLFAPTRLSCMLAKLEIKQLGSRSQPGIKFMIPLSGYGGTSNLILEDVKKLSDSYLITMNDLIPGKESKVVFSIRNTGSRAAFVRAVCFKESQRKVLLDPKVLRIFPDKFVLKERTQEHITLVYTPSSRKNGEKPATELLTVYMFGGDEISRQQYRRAQMHTPGILKQILPEHSVLQHIDFTEAFQDEPLIDEVCDLPQRPNDIELFYGSMRKITLSVIGEFRGTICSREFLQPSSSAESKSNFSSDSKTSGKQSGNVLLDVLPVKGPQGPPFLSQSAHPAQDTAASEEGWAVHPEHLILVAPSSCDLAKTGCFQIINNSVILLKFELYWPAHCLTVTPQHGCIMPESKIQILVSPNFSVSTKESVCPWTGLIYIHCDNGQKKIVKVQIREDLTQEPLPHLPSSGTSGILAPAPEPSISRLTKLITKPPSTKVEIRSKTVIFPPTEPGRTSENYLELENCGPTDVKWHLSSFAPPYVKGVDETEDVFRATYTTFRCSPISGTLEGHGIQKVSIIFLPRDKGNYAQFWDVECHPAKEPHMKHTLRFQLSGQSIRAENDPEDSCSSRDALIKVDTAVTSRRRAVSETAAHTPGRQLNSSHHGVYAPKDVYTFLPTKLGESRTLKINLRNNSFSTHALKFLSPREPFHIRHSKYTLRARHYIHIPVHFRPEAVGRFEALLVIQTDEGKSIAIRLIGESLGKS
Protein: Structural maintenance of chromosomes protein 3 (Cohesin complex Psm3 subunit) (O42649)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
Subcellular location: Nucleus {ECO:0000269|PubMed:11069892}. Chromosome {ECO:0000269|PubMed:11069892}. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. At anaphase, the rad21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation.
Interaction partners:
- Sister chromatid cohesion protein pds5
- Separin
- Cohesin subunit rad21
- Meiotic recombination protein rec8
- Sister chromatid cohesion protein mis4
- Cohesin subunit psc3
- Structural maintenance of chromosomes protein 1
- Meiotic recombination protein rec11
- N-acetyltransferase eso1
- Structural maintenance of chromosomes protein 6
Sequence:
MYITKIVIQGFKSYKDYTVIEPLSPHHNVIVGRNGSGKSNFFAAIRFVLSDAYTHLSREERQALLHEGPGATVMSAYVEVTFANADNRFPTGKSEVVLRRTIGLKKDEYSLDKKTVSKTEVINLLESAGFSRSNPYYIVPQGRVTSLTNAKDSERLELLKEVAGTQIYENRRAESNKIMDETIQKSEKIDELLQYIEERLRELEEEKNDLAVYHKKDNERRCLEYAIYSREHDEINSVLDALEQDRIAALERNDDDSGAFIQREERIERIKAEITELNHSLELLRVEKQQNDEDYTNIMKSKVALELQSSQLSRQIEFSKKDESSKLNILSELESKISEKENELSEILPKYNAIVSEADDLNKRIMLLKNQKQSLLDKQSRTSQFTTKKERDEWIRNQLLQINRNINSTKENSDYLKTEYDEMENELKAKLSRKKEIEISLESQGDRMSQLLANITSINERKENLTDKRKSLWREEAKLKSSIENVKDDLSRSEKALGTTMDRNTSNGIRAVKDIAERLKLEGYYGPLCELFKVDNRFKVAVEATAGNSLFHIVVDNDETATQILDVIYKENAGRVTFMPLNKLRPKAVTYPDASDALPLIQYLEFDPKFDAAIKQVFSKTIVCPSIETASQYARSHQLNGITLSGDRSDKKGALTAGYRDYRNSRLDAIKNVKTYQIKFSDLQESLEKCRSEIESFDQKITACLDDLQKAQLSLKQFERDHIPLKDELVTITGETTDLQESMHHKSRMLELVVLELHTLEQQANDLKSELSSEMDELDPKDVEALKSLSGQIENLSHEFDAIIKERAHIEARKTALEYELNTNLYLRRNPLKAEIGSDNRIDESELNSVKRSLLKYENKLQIIKSSSSGLEEQMQRINSEISDKRNELESLEELQHEVATRIEQDAKINERNAAKRSLLLARKKECNEKIKSLGVLPEEAFIKYVSTSSNAIVKKLHKINEALKDYGSVNKKAYEQFNNFTKQRDSLLARREELRRSQESISELTTVLDQRKDEAIERTFKQVAKSFSEIFVKLVPAGRGELVMNRRSELSQSIEQDISMDIDTPSQKSSIDNYTGISIRVSFNSKDDEQLNINQLSGGQKSLCALTLIFAIQRCDPAPFNILDECDANLDAQYRSAIAAMVKEMSKTSQFICTTFRPEMVKVADNFYGVMFNHKVSTVESISKEEAMAFVEG
Protein: NAC domain containing protein 36 (F4IME8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Nodulin-related protein 1
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein eS24z
- Small ribosomal subunit protein eS24y
- Small ribosomal subunit protein eS21z
- Small ribosomal subunit protein eS21y
- Small ribosomal subunit protein eS28z/eS28y
- Large ribosomal subunit protein eL38z/eL38y
- Small ribosomal subunit protein eS1z
Sequence:
MGKDIELPGFRFHPTEEELLDFYLKNMVYGKRSSVEVIGFLNIYRHDPWDLPGLSRIGEREWYFFVPRERKHGNGGRPSRTTEKGYWKATGSDRKIISLSEPKRVIGLKKTLVFYRGRAPGGSKTDWVMNEFRMPDNCSLPKDVVLCKIYRKATSLKVLEQRAEMEAKMNQTCPNSPLSSSETISFVGKEENMMTSFRAPQVIAMEEANKIQMHQENAKTEEKQREAETKEPSSSLKLPFGSLPELQLPKPGVEWDQLLSISPWLQNLTPIVNIYW
Protein: Peroxidase 34 (Atperox P34) (EC 1.11.1.7) (ATPCb) (Q9SMU8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000305}. Vacuole {ECO:0000305}. Note=Carboxy-terminal extension appears to target the protein to vacuoles.
Interaction partners:
- Thioredoxin-like 4, chloroplastic
Sequence:
MHFSSSSTSSTWTILITLGCLMLHASLSAAQLTPTFYDRSCPNVTNIVRETIVNELRSDPRIAASILRLHFHDCFVNGCDASILLDNTTSFRTEKDAFGNANSARGFPVIDRMKAAVERACPRTVSCADMLTIAAQQSVTLAGGPSWRVPLGRRDSLQAFLELANANLPAPFFTLPQLKASFRNVGLDRPSDLVALSGGHTFGKNQCQFILDRLYNFSNTGLPDPTLNTTYLQTLRGLCPLNGNRSALVDFDLRTPTVFDNKYYVNLKERKGLIQSDQELFSSPNATDTIPLVRAYADGTQTFFNAFVEAMNRMGNITPTTGTQGQIRLNCRVVNSNSLLHDVVDIVDFVSSM
Protein: NAD-dependent protein deacetylase sirtuin-1 (Sirtuin 1) (E7F8W3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Cellular tumor antigen p53
- Forkhead box O3A
- Nicotinamide phosphoribosyltransferase
- Nicotinamide phosphoribosyltransferase
- Forkhead box O3b.
- Glutamine-dependent NAD
- Ubiquitin-like modifier-activating enzyme ATG7
- Forkhead box protein O1-A
- Ribosomal RNA-processing protein 8
- Histone deacetylase 1
Sequence:
MADGENKRAESAEPDEPLPKKPRLLELSGDSEHSATAGADTLDEKPARMDESQQALSINNNNNTRPTEPGQPADPEPEISELTDEGVHPNGFTSPDLLRDDDDCSSRASSSDWTPQPQIGSYRFIQQHIMRGTDPRAILKDLLPETVLPPDLDDMTLWQIIINISEPPKRKKRKDINTLEDVVRLLNERKKILVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIDYFRRDPRPFFKFAKEIYPGQFQPSPCHRFISMLDKKGRLLRNYTQNIDTLEQVAGIQKIIQCHGSFATASCLICKHKVDCEAIREDIFNQVVPHCPRCPSDVPYAIMKPDIVFFGENLPEFFHRAMKQDKDEVDLLIVIGSSLKVRPVALIPSSIPHDVPQVLINREPLPHLNFDVELLGDCDVIVNELCHRLNGDFQQLCYNSSRLSEITEKPAAPEHTENTSADHSHADAEHIENTSADHSHADAEHIENTSADRDDAKHTENTPTDHADAEHTKNTSADHANAEHTENTSAGHVNAEHIEHMSKDHANPKDDQSSLSVNEEELASPAAETHALDSTEISAHTERSKEADAVNTDDAACVKDEENTDRLRVEMRRRCWRSRICQSPISKRLGASQYLFQAPNRYVFHGAEVYSSSEDESSSSCGSESDGSFQHEDSEVEENGAAMTDKETDTETVQDSEHRRLQTHCTQHTQ
Protein: Microtubule-associated protein 70-5 (AtMAP70-5) (70 kDa microtubule-associated protein 5) (Q8GYX3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant-specific protein that interact with microtubules and regulates microtubule dynamics. May play a role in anisotropic cell expansion and organ growth. In association with MAP70.1, is essential for the normal banding pattern of secondary cell wall and for the proper development of xylem tracheary elements and wood formation.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17567681, ECO:0000269|PubMed:20399097}. Note=Associated to microtubules in tracheary elements.
Interaction partners:
- 65-kDa microtubule-associated protein 8
- Protein trichome birefringence-like 12
- Uncharacterized protein At4g24700
- AT2G45990 protein
- Interactor of constitutive active ROPs 5
- Expressed protein
- Small ribosomal subunit protein cS23z
- Maternal effect embryo arrest 9
Sequence:
MTAAENPFVSDTSSLQSQLKEKEKELLAAKAEVEALRTNEELKDRVFKELRENVRKLEEKLGATENQVDQKELERKKLEEEKEDALAAQDAAEEALRRVYTHQQDDDSLPLESIIAPLESQIKIHKHEISALQEDKKALERLTKSKESALLEAERILRSALERALIVEEVQNHNFELRRQIEICQDENKFLEKINRQKVLEIEKLSQSIVELEEAILAGGTAANAVRDYRRQISQLNDEKRTLERELARVKVSASRVALAVANEWKDENDRVMPVKQWLEERRILHGEMQKLKDKLAVSERTAKAESQLKERLKLRLKTIEDGLKGPNTFFVSPTTKTEKSGKILGFLTSGGGSKKRSSSQLRGSVTGRIHAMNQPIDRVGESDEMENSKITANGLTDQHEEDSERKTEEDGNVYSEDMVSGFLYDRLQKEVIALRKLCESKEGTINAKNEEIKMLLKKVDALTKAIEVETKKAKREAAAREKENALAMLNEESKLCRKAKLPRSRIPNPRCQ
Protein: Nitrogen regulatory protein P-II (PII signal transducing protein) (Q9L422)
Organism: Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Interaction partners:
- Ammonium transporter
- Ammonium transporter
- Ammonium transporter
- Asr0485 protein
- Glutamine synthetase
- Acetylglutamate kinase
- Global nitrogen regulator
- Biotin carboxyl carrier protein of acetyl-CoA carboxylase
- Nitrite reductase
- Glutamine-dependent NAD
Sequence:
MKKVEAIIRPFKLDEVKIALVNAGIVGMTVSEVRGFGRQKGQTERYRGSEYTVEFLQKLKVEIVVEDNQVDMVVDKIIAAARTGEIGDGKIFISPVEQVIRIRTGEKNTEAV
Protein: Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) (P51957)
Organism: Homo sapiens (Human)
Function: Protein kinase that seems to act exclusively upon threonine residues (By similarity). Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:21685204}. Cytoplasm {ECO:0000269|PubMed:21685204}.
Interaction partners:
- Protein fantom
Sequence:
MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAESNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELATISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQPENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLGSSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMNF
Protein: Probable enoyl-CoA hydratase EchA17 (EC 4.2.1.17) (P9WNN3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Could possibly oxidize fatty acids using specific components.
Interaction partners:
- 3-hydroxybutyryl-CoA dehydrogenase
- Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3
- Conserved protein
- Probable conserved ATP-binding protein ABC transporter
- Conserved protein
- Phosphoserine phosphatase SerB2
- Probable acyl-CoA dehydrogenase FadE23
- Acyl-CoA dehydrogenase FadE7
- Probable acyl-CoA dehydrogenase FadE4
- Probable acyl-CoA dehydrogenase FadE2
Sequence:
MAAVTPTVPEFVNVVVSDGSQDAGLAMLLLSRPPTNAMTRQVYREVVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTAARIRQQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLIPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGISDVYELAPAERIAAERRRYVEVFAAGQGGGSKGDRGGR
Protein: Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1) (Q9BY11)
Organism: Homo sapiens (Human)
Function: Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity). Binds to membranes via its F-BAR domain and mediates membrane tubulation.
Subcellular location: Cytoplasm {ECO:0000250}. Cell projection {ECO:0000250}. Synapse, synaptosome {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}. Membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Synapse {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Colocalizes with MAPT in axons. In primary neuronal cultures, present at a high level in presynaptic nerve terminals and in the cell body. Colocalizes with DNM1 at vesicular structures in the cell body and neurites (By similarity). Associates with membranes via its F-BAR domain. {ECO:0000250}.
Interaction partners:
- Protein kinase C and casein kinase substrate in neurons protein 3
- Protein kinase C and casein kinase substrate in neurons protein 2
- Huntingtin
- Protein cordon-bleu
- Dynamin-1
- Synaptojanin-1
- Actin nucleation-promoting factor WASL
- Cordon-bleu protein-like 1
- Sine oculis-binding protein homolog
- Cdc42-interacting protein 4
Sequence:
MSSSYDEASLAPEETTDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTTKKEKQPKKAEGVALTNATGAVESTSQAGDRGSVSSYDRGQPYATEWSDDESGNPFGGSETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI
Protein: Integrin alpha-E (HML-1 antigen) (Integrin alpha-IEL) (Mucosal lymphocyte 1 antigen) (CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain] (P38570)
Organism: Homo sapiens (Human)
Function: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Integrin beta-7
- Cadherin-1
- T-cell surface glycoprotein CD8 alpha chain
- Forkhead box protein P3
- T-cell surface glycoprotein CD4
- L-selectin
- Integrin beta-1
- Fibronectin
- Killer cell lectin-like receptor subfamily G member 1
- Early activation antigen CD69
Sequence:
MWLFHTLLCIASLALLAAFNVDVARPWLTPKGGAPFVLSSLLHQDPSTNQTWLLVTSPRTKRTPGPLHRCSLVQDEILCHPVEHVPIPKGRHRGVTVVRSHHGVLICIQVLVRRPHSLSSELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDVNTARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQFRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVHGENLFGAEYQLQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIRKAQLKSENLLEEEN