wanglab/gogpt-training-data huggingface dataset:
Protein: Glutathione S-transferase omega-like 2 (EC 2.5.1.18) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (O94524)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB). May be involved in cell wall organization and biogenesis (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}. Golgi apparatus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Ubiquitin-activating enzyme E1 1
- Glutathione S-transferase 3
- Uncharacterized kinase C24B10.02c
- General alpha-glucoside permease
- Inositol phosphoceramide mannosyltransferase 1
- NADH kinase pos5, mitochondrial
- Inositol phosphoceramide mannosyltransferase 2
- Inositol phosphoceramide mannosyltransferase 3
Sequence:
MSNTHITDWSSKDGEFRRQVSSFRERISPEHKYFQPEKDRYHLYVSYACPWAHRTLIVRKLKGLENVIPVHVVGWLMGPNGWNFDKENDSTGDPLYNSPYLRNLYFRADPNYNMRFTVPVLWDSKYNTIVNNESAEIIRMFNDAFNEVIEDEEKRVVDLYPSSLRTKIDELNDYFYDTVNNGVYKTGFATTAEAYEKNVRVVFQGLDRLEQVLKESKGPFLLGDHLTETDVRLYTTIVRFDPVYVQHFKCNIGTIRHNYPHINQWLKRLYWKHPAFHETTDFKHIKCHYTQSHTQINPLGITPLGPIPNVEYF
Protein: Receptor activity-modifying protein 1 (Q867C0)
Organism: Sus scrofa (Pig)
Function: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O60894}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:O60894}.
Interaction partners:
- Calcitonin gene-related peptide type 1 receptor
- Calcitonin receptor
- Pro-adrenomedullin
- Calcitonin receptor-stimulating peptide 3
- Calcitonin receptor-stimulating peptide 2
- Calcitonin receptor-stimulating peptide 1
- Receptor activity-modifying protein 3
- Islet amyloid polypeptide
- Receptor activity-modifying protein 2
- GNAS complex locus
Sequence:
MARGLRGLPRRGLWLLLVNHLFLATACQDTDHAALLRKYCLPQFQVDMEAIGKALWCDWDKTIGSYKDLSDCTRLVAQRLDCFWPNAAVDKFFLGVHQQYFRNCPVSGRALQDPPSSVLCPFIVVPILATLLMTALVVWRSKRPEGIV
Protein: Estrogen receptor 2 (H0ZRT6)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR002527}.
Interaction partners:
- Estrogen receptor
- histone acetyltransferase
- Progesterone receptor
- Nuclear receptor coactivator
- Nuclear receptor coactivator
- Aromatase
- Nuclear receptor interacting protein 1
- histone acetyltransferase
- Nuclear receptor coactivator 5
- Caveolin
Sequence:
MSLCTSSHKDFSQLLPLQDIGCNKAEIKNSPAGVISPVPYNCNQSTLTAEHSPLYIPSSFMENRHEYSTMAFCSPAMVNYNIGSNFGDAEGVTARQTSSPSALWAAPGHLSPLSLHCQSSLLYPEQPKSLWCEAHPMEPVLPGSRETLKRKINDNECTSPIANNPGSKKDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMMKCGSRRERCGYRILRSHRNAEERARCLGRARRYNEAATRVKEILLSAVSPEQFVLTLLEAEPPHVLVSRPSKPFTEASMMMSLTKLADKELVHMIGWAKKIPGFIDLSLYDQVRLLESCWMEVLMIGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLAMTSRFRELKLQHKEYLCVKAMILLNSSMFPLSAEEPESNRKLHHLLNVVTEALVWVIAKSGIPSQQQTTRLANLLMLLSHVRHASNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGQRKSLATHPEFGPLEQMEPGDSLRNGAPQ
Protein: WD repeat-containing protein 26 (A0A499FIZ0)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MASLGEETLASASSSSDSDTGGASPPPRKKPRASAAEGVGEPGASAGRAGLSPPSSSSSSSSSSSSSVVVVVGLPPAAAPPAAAAVPHRSSGHSLVSGSIMQANGAGGGGGGGGGGGGGGGGGGGQGQTPELACLSAQNGESSPSSSSSAGDLAHANGLLPSAPSAASNNSNSLNVNNGVPGGAAAASSATVAAASATTAASSSLATPELGSSLKKKKRLSQSDEDVIRLIGQHLNGLGLNQTVDLLMQESGCRLEHPSATKFRNHVMEGDWDKAENDLNELKPLVHSPHAIVVRGALEISQTLLGIIVRMKFLLLQQKYLEYLEDGKVLEALQVLRCELTPLKYNTERIHVLSGYLMCSHAEDLRAKAEWEGKGTASRSKLLDKLQTYLPPSVMLPPRRLQTLLRQAVELQRDRCLYHNTKLDNNLDSVSLLIDHVCSRRQFPCYTQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDLDGNLLDSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTDRNIVQEDHPIMSFTISKNGRLALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWGPAPFIDHQNIEEECSSMDS
Protein: Oil body-associated protein 2C (Q9C7N3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Oil body-associated protein 1B
- Oil body-associated protein 1A
Sequence:
MALSGGDDQVPPGGPMTVSTRLIDAGSTIMQRRLPVKQMNTHVSTFAIYGGDMSRLIGTHHYVHRVNDEFLQCAVYASDRSDAPLIGIEYVISDRLYETLSEDEQKLWHSHAYEVKSGSWAYPRLPEVVAAPELKNIAKTYGKFWCTWQIDRGDKLPMGAPELMMSPQGVGQGVLRPELVKRRDEKYNISTDDLKHTRAEIAEPEWINPMADYWKQHGKCFVLDIATVEMNRHAQFP
Protein: DNA damage-induced apoptosis suppressor protein (Nitric oxide-inducible gene protein) (Q6NZG4)
Organism: Mus musculus (Mouse)
Function: May be an anti-apoptotic protein involved in DNA repair or cell survival.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17515607}. Nucleus {ECO:0000269|PubMed:17515607}. Note=Accumulates in the nucleus in response to stress.
Interaction partners:
Sequence:
MNKRRKFLFASVLAVQNSNFIYPSCQRCFSKIILESKRFTCPKCGSSGDTGSTNYRYKLSLKVAESSKLFFITVFGSCLDTFFGLTATGLHRYLGDSIKNLETLDSGRTQSLLTTAVEKCFVGQSFVFGVTNFGDVCGHDSDSSNFQQPCCKHRGEVRTLVASQIILPSPHVKGFTVIAYLHPLLHKKPHCGSQEHSSQSLTSDDSDSDLNNIQGSGNTSWFSESSVGEDFFRYWEPSLELTSSDSQVTSSDDFPASKQIMASGTPNQNRHCISVSEVTSSKNCHDSLQSLWSLHSCMDKNNTTGKLGEELGLPSPVCNSCHESRLSDSHFFPSQMQEPFEEHNLECYSKAEKNDYSQYDIACYQHHEVNTTPILQQRSSAFSLSSLKPEETANPSQNSDSLIWDDLPLSESLNKFLAVVESEVAVTEIDAKNRKQGMDKSIDKCHKNYSRLSLTPWRNTRALNTSCFSLRSSQAMMKDSGKEALFSNCKSNSSPHIQKESKADKTEAAVSIAGSRSDISEDFLPDTCSSALFTSSKDREAFITQKRTSGVLQQRNEISCRPSTSISDCSDLRSRYFTGCGQKLHSGTKGKLAIQNCSKKYSDASDLHKLENKHRWPKKEDDNFTICRKLTYPLETLCSSPESINTSKEMPYRPSNNNLTPSSSGDHEGSYNASADLFDYIAKDKDIGTEITKIPQDNLLPLEVPCTENYPINENRGQPSQKPSLQSISPSRYSRPRSQSDSECDFEESQDFVPCSQSTPVAGFHQRIHGLNGASKILPSIYSNPNANYKNRKNSPLTGQYQATSACSKNVKAFRQKPESPFVSSLTQANVFNHCPAAESLGNDVDEWVPPTTKKVFISDILGFRVMGLRKCLDLHYSPDPKELPRKKLIKVTHKTNI
Protein: Protein-tyrosine sulfotransferase (EC 2.8.2.20) (Tyrosylprotein sulfotransferase) (Q3EDG5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:19666544}; Single-pass type I membrane protein {ECO:0000269|PubMed:19666544}.
Interaction partners:
- Phytosulfokine receptor 2
- Phytosulfokine receptor 1
- Protein GOLVEN 11
- Protein PSY1
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- At2g15730
- Tyrosine-sulfated glycopeptide receptor 1
- Putative defensin-like protein 228
- Root meristem growth factor 10
Sequence:
MQMNSVWKLSLGLLLLSSVIGSFAELDFGHCETLVKKWADSSSSREEHVNKDKRSLKDLLFFLHVPRTGGRTYFHCFLRKLYDSSEECPRSYDKLHFNPRKEKCKLLATHDDYSLMAKLPRERTSVMTIVRDPIARVLSTYEFSVEVAARFLVHPNLTSASRMSSRIRKSNVISTLDIWPWKYLVPWMREDLFARRDARKLKEVVIIEDDNPYDMEEMLMPLHKYLDAPTAHDIIHNGATFQIAGLTNNSHLSEAHEVRHCVQKFKSLGESVLQVAKRRLDSMLYVGLTEEHRESASLFANVVGSQVLSQVVPSNATAKIKALKSEASVTISETGSDKSNIQNGTSEVTLNKAEAKSGNMTVKTLMEVYEGCITHLRKSQGTRRVNSLKRITPANFTRGTRTRVPKEVIQQIKSLNNLDVELYKYAKVIFAKEHELVSNKLISSSKRSIVDLPSELKSVLGEMGEEKLWKFVPVALMLLLIVLFFLFVNAKRRRTSKVKI
Protein: Serine/threonine-protein kinase PTK2/STK2 (EC 2.7.11.1) (P47116)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential determinant for high-affinity spermidine transport. Required for the activation of the plasma membrane proton pump PMA1 via phosphorylation of 'Ser-899'.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Plasma membrane ATPase 1
- Tubulin alpha-3 chain
- Serine/threonine-protein kinase SKY1
Sequence:
MAGNGKDKEVDKSPSVSTLKLLGKRLFNSSSHTDNSSLLLSAEQLGNGRSLRKRPTSPSISGSGSGGNSPSSSAGARQRSASLHRRKNNASVGFSNGSVSSHKSSVALQDLIKHNNNPYLNSPSDILGTGTGIASTRDRDRAVLDREKEKERARNKERNTHHAGLPQRSNSMASHHFPNENIVYNPYGISPNHARPDTAFADTLNTNKENDLSFYMHDGNSKIRMLPLPIANPNDFLPEDMKQYSVHLTDNFVFDTDNKPIGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFREFEVSYDNFINHQNPHFRDKGCHKPGPGSEYSLARNFKNTDATRIAWRLADPNPATRYTMDDLFNDPFFQQIETCVEPNDDDLVRVPELRKSTSTNDFSENSLDAPHDQEVIHTSNPFLKKETLTSKPRSMLEIAESPSLKQKSKVKDSAKTKTHDVGDEGGNESTKPKQQDKKENLKKDEVKNGDKDKVIEEATTTNVDSILEKPTPTSTKVEDNLSEDDSTMKELKSMLNSTPTTPTHNGPTPLPAKAGTQLDKRMSDLSLKSETPASTKNFSAPNVSSSSNSLRSLGSPSVSSSKKKKVIHHHLDITNSVTNMSSVSAFISR
Protein: DNA polymerase kappa (EC 2.7.7.7) (P34409)
Organism: Caenorhabditis elegans
Function: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA polymerase
- DNA repair protein REV1
- Proliferating cell nuclear antigen
- DNA polymerase theta
- DNA repair protein RAD51 homolog
- XPA C-terminal domain-containing protein
- Helicase ATP-binding domain-containing protein
- Fanconi-associated nuclease 1 homolog
- DNA polymerase eta
- Methylated-DNA--protein-cysteine methyltransferase
Sequence:
MLTFNDNKAGMNGLDKEKITKVIEENTSASYSSFSKKQQSRIEEKVLEIKNRLQTATREERQKSEILMENLEMKLESSRDLSRDCVCIDMDAYFAAVEMRDNPALRTVPMAVGSSAMLSTSNYLARRFGVRAGMPGFISNKLCPSLTIVPGNYPKYTKVSRQFSQIFMEYDSDVGMMSLDEAFIDLTDYVASNTEKKTFKRHRFGGDCPCWLPRFDENENTLEDLKIEESICPKCEKSRKIYYDHVEFGTGREEAVREIRFRVEQLTGLTCSAGIASNFMLAKICSDLNKPNGQYVLENDKNAIMEFLKDLPIRKVGGIGRVCEAQLKAMDIQTVGDMNLKKNLYPLCFTPLSQESFLRTALGLPGRPSESDPRRKSISVERTFSPTSDFNILLEEHQEICRMLEEDVRKSGIVGGKTVTLKLKLSSFDVLTRSLTPSDVVKSLEDIQKFSLELLEKEKGKEIRLLGVRLSQLIFEEDEKKRSKTITEFWNEKKLQIQNLQGSENVDDDDVIMMDTRPCPICGTDVENRLDVMNCHVDECILKVQNDDGPELICVSVENKSTQKPERPSTKKRKLQEKRPKAKKMVTIDSFWKKSG
Protein: Defective proboscis extension response 1, isoform A (Defective proboscis extension response 1, isoform B) (IP20514p) (A1ZBY3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Dpr-interacting protein eta, isoform B
Sequence:
MSLPSRANIGLLNWLIGWLLLLSMVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQINTEPKMSLSYTFNVVELKAEIFGPSDLMVKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPTVAKTSSVYVHVIIGEHPAAMQHNSSSNSNSFYCGICCMLLSIVSCCLQHFYETGCGYLHAAAALAKSAGLGPPKRATLTTSETGISAAEVAAAAGASAAVASALATCNMLRERPAAIRCLR
Protein: Gap junction alpha-4 protein (Connexin-37) (Cx37) (P35212)
Organism: Homo sapiens (Human)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Interaction partners:
- Gap junction alpha-5 protein
- Gap junction alpha-1 protein
- Gap junction gamma-1 protein
Sequence:
MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV
Protein: Choline/carnitine acyltransferase domain-containing protein (C8V1G3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Carnitine acetyl transferase FacC
- propanoyl-CoA C-acyltransferase
- Lipid transfer protein, putative
- propanoyl-CoA C-acyltransferase
- Peroxisomal targeting signal receptor
Sequence:
MFTAAARSRFSSTLARPRLAPTNSLLARSSVASTMAPRRKASSVPEGYKEDLSKGNMLRFEDSLPRLPVPSLEETGRRYLKSVHAVVSEAEYENTKKAVEEFIRPGGAGQTLQERLLARAADPKHKNWLTEWWNNAAYLGYRDPVIPYVSYFYSYRDDRARRDPVKRAAAITTAALEFKSQVDNGSIEPEYLRKIPQAMSSYQYMFNCCRIPAEPADYPQKYPAEENQHIVVVRKNQFFKVPVVIDGRPLNVSELEQQFERIYKIAKKAPPVGVLTVANRDHWTAARKKLLEAHPNNANALRDIESSGFVVCLDDASPVTLEERAEQYWHGDGHNRWFDKPLQFIVNENGTAGFMGEHSMMDGSPTHRLNDHLNALIFNNKIDLSAKPVRSNLPDPRPIDFHLNEEVQEAIDVAAKEHRQQIAAHELRVQAYQGYGKGLIKKFKCSPDAYVQMIIQLAYFKMYGKNRPTYESASTRKFAEGRTETIRTVSDESVAFCKAITNSSVPREEAVRLFRTALAAHSKYTAEASDGKGVDRHLFGLKKLVREGEPLPAIFSDPAYSYSSSWYLSTSQLSSEYFNGYGWSQVIDDGFGIAYMINENSLNFNIVCKRIGAERMSYYLNEAAGDIRDMLMPDLAAEAEKAKL
Protein: Fatty acid-binding protein 10-A, liver basic (Zf-FABP10) (Zf-Lb-FABP) (Fatty acid-binding protein, liver) (Liver bile acid-binding protein) (L-BABP) (z-L-BABP) (Liver-type fatty acid-binding protein) (L-FABP) (Liver-type FABP) (Q9I8L5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Binds hydrophobic ligands, such as cholate, in the cytoplasm. May be involved in intracellular lipid transport (By similarity). Binds one cholate per subunit.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Elastase 3-like
- Fatty acid-binding protein 2, intestinal
- Vitamin D-binding protein
- Forkhead box A3.
- Hematopoietically-expressed homeobox protein hhex
- Betaine--homocysteine S-methyltransferase 1
- Myosin light chain 2 Mlc2a
Sequence:
MAFSGTWQVYAQENYEEFLRAISLPEEVIKLAKDVKPVTEIQQNGSDFTITSKTPGKTVTNSFTIGKEAEITTMDGKKLKCIVKLDGGKLVCRTDRFSHIQEIKAGEMVETLTVGGTTMIRKSKKI
Protein: Potassium voltage-gated channel subfamily E member 3 (MinK-related peptide 2) (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2) (Q9WTW2)
Organism: Mus musculus (Mouse)
Function: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9JJV7, ECO:0000250|UniProtKB:Q9Y6H6}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9Y6H6}. Cytoplasm {ECO:0000250|UniProtKB:Q9JJV7, ECO:0000250|UniProtKB:Q9Y6H6}. Perikaryon {ECO:0000250|UniProtKB:Q9Y6H6}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9Y6H6}. Membrane raft {ECO:0000250|UniProtKB:Q9Y6H6}. Note=Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal neurons. {ECO:0000250|UniProtKB:Q9Y6H6}.
Interaction partners:
- Potassium voltage-gated channel subfamily KQT member 1
- Intermediate conductance calcium-activated potassium channel protein 4
- Potassium voltage-gated channel subfamily E member 2
- Potassium channel TASK2
- Inward rectifier potassium channel 13
- Potassium voltage-gated channel subfamily E member 1
- Potassium voltage-gated channel subfamily E member 4
- Voltage-gated inwardly rectifying potassium channel KCNH2
- Potassium voltage-gated channel subfamily E regulatory beta subunit 5
- Sodium channel regulatory subunit beta-3
Sequence:
METSNGTETWYMSLHAVLKALNTTLHSHLLCRPGPGPGPDNQTEDRRASLPGRNDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI
Protein: Slo-interacting protein 1 (dSLIP1) (Q8MR31)
Organism: Drosophila melanogaster (Fruit fly)
Function: May selectively reduce calcium-activated potassium channel (Slo) currents by reducing the number of Slo channels in the plasma membrane.
Interaction partners:
- TBP-associated factor 3
- Eukaryotic translation initiation factor 4G1, isoform B
Sequence:
MSIADVEYEYVVLKINGYDISHLSRYEAVQKFLQSKETLVVEIRRQKHNALDLELKHGSNAKISKVDNPGELSVLTDKSAEGTITAASASQQINCPSSTSLKEIETKTPVVLTLRARSHEDRLGSLQAASKETQTQSVVGTDVLKDNDLVNTITDNFIEHEHHLFEQCLEPEIDIEEVTLVKGVEQSSSNQIGLIVTSSGIQQSSTDTNKGDILGNVLEHSEDVFISGVQPESIAYRDGRLRQGDQILRINGLDVKNQEELETQIARSSTSVTLLVSRILYPEDDDDEDIHFEYANTFLPDDYTNVVDKLDKVLLTHVKSLEELSNKSAMQSDECYHIPEKNSSDSNVKISSLAKNIIEQSTKSCSKIKLRPNANLDYKKKFNLPLSQEEVHLQYEYDESEHIYETIPEDSESEPVYCSPYQRSNDKTSIGCSSPIASRPAESLERTMQQQTQRVAQWLGLKPQYQKTRQTLVGRPPPLKLVQQPTCSRVFTLRSTLTNTSASSSSGVAYSSYGQNNVVTGNAAAPGEEVDNSSSAYNTGDSNNSASPHQNTTNPDEAIATGRKLDSTVIDSPNDHLDATGVSTMLLLPFGKSGRIGLCSSNLPTAYVSERYTNVGSENEIHPLKSDIEILRVKPTDDSYSHCPQFNAPNLSSYHFVSSQEVANRCHISTSLQKNATLLNGESAEEIPMVWKVKRRPDGTRYIVKRPVRNRPQVALRKNMRYNEVTTTEDDTISEVKIGRYWTKEERKRHIERAREKRHHQTQQQQQ
Protein: Probable catechol O-methyltransferase 1 (EC 2.1.1.6) (O42898)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable catechol O-methyltransferase 2
- Alcohol dehydrogenase
- Alcohol dehydrogenase 4
- Copper amine oxidase-like protein cao2
- Putative S-
- Probable S-
- Copper amine oxidase 1
Sequence:
MPHMEDNGSEKEQLFLQHIQNLPQERLDAIRGHPELVLKEIDEFTYPDGSGVRMCIGDVKGGFIVGKIRERKPKIMVELGGYLGYSAILFGNEISKIPGGRYYSLEVNEDYAKIAYELVKLAGLDEIVTIMIGKACDSLVELQQKLLHKDLGFQALDMVFIDHWKDLYVPDLRVIESLNMIAPGTLLVADNIITPGAPEYHKYVNMSPEERRGYQAKVRNVNGFDFIGRWDLIYKTETKEFEGVIRNKHRKDAVDVTECVGYAKKD
Protein: Large ribosomal subunit protein uL13w (60S ribosomal protein L13a-4) (Q9FKC0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL8y
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein uL24z
- Large ribosomal subunit protein eL43y
- Large ribosomal subunit protein uL3y
- Large ribosomal subunit protein uL10x
- Large ribosomal subunit protein uL10y
- Large ribosomal subunit protein uL11x
- Large ribosomal subunit protein eL24y
Sequence:
MVSGSGICSKRVVVDARHHMLGRLASITAKELLNGQKVVIVRCEEICLSGGLVRQKMKYMRFLRKRMNTKPSHGPIHFRAPSKIFWRTVRGMIPHKTKRGAAALARLKVYEGVPTPYDKIKRMVIPDALKVLRLQAGHKYCLLGRLSSEVGWNHYDTIKELETKRKERAHVVYERKKQLNKLRVKAEKVAEEKLGAQLDILAPVKY
Protein: A disintegrin and metallopeptidase domain 4 (ADAM4) (Q8CGQ2)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- A disintegrin and metallopeptidase domain 3
- Predicted gene 4787
Sequence:
MAPFLRPSTWTLALLRGALWLSVLWALLSPACCSRSPPKWRFSTSEIVIPRKVPQRMGKSDMSGHITYSMRFRGQRHVVHMKLKKNMIPQNFPVYTSNDQGAQQKDYPFVPRDCYFYSFLEGVPGSQAILDTCTGGLKGMIQVDDFTYEIKPLASSSKFEHVISLLVVDERSRESKKCRNDEIMAKAGDLSEETKLAGSPRAAPVYLWRYHLKSVGIHYTVTHDLFKQTGSNSSTSVELILIMNSISDSIYKISGLIVYARGVWIWNTKNLHTVPGENPHLDPWSVMAGFGVWKSKELHDLYATTAILLASRPKNTDYGSFQNGLCNPNWGVLFTYVGKNHLFLAGSFLAHAVGHLLDVSHDTPGCVCFRRSSCLMDEFPTLHDMISNCSHNELHRRIHDWDPCLSLELKTAKEVNMYEVPRCGNKRVEASEKCDCGSVKDCTTDKCCEVNCEFTQGSSCAAGGCCLSCKFAPTGTICRDKNGICDLPEYCSGASEHCPGNFYIMDGTPCSPLAVCIAGNCSDRHLQCQALFGYQVKDGSPACYNELNVKGDRFGNCGIRIIRGGSQPVPCQKEDVFCGMIHCDGVSHIPGGGEHTTFYHLKVQDVKEEQCFGYDAHHGTELPEMGLVVDGATCGPGKYCKAQRCVAHPTLNFNCNISSCNFRGVCNNKGNCHCVRGWQPPHCLQIGKGGSTNSGPPPTTQKKHQAEIHVSANRLIVILSIRMILILASILLGAVFKAIFVSETTEEEQHSAVNRQLTSYQTI
Protein: Interferon lambda-3 (IFN-lambda-3) (Interleukin-28B) (IL-28B) (B4ER10)
Organism: Gallus gallus (Chicken)
Function: Cytokine which plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exhibits antiviral activity against the H5N1 influenza A virus. Induces the expression of the antiviral MX protein in epithelial-rich tissues, such as intestine, trachea and lung.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Uncharacterized protein.
- Interferon lambda receptor 1
- Interleukin family protein
Sequence:
MVCYGVTIILVGTLGSLLVGAFPQVTPKKSCSLSKYQFPAPLELKAVWRMKEQFEDIMLLTNRKCNTRLFHRKWDIAELSVPDRITLVEAELDLTITVLTNPTTQRLAETCQQPLAFLTQVQEDLRDCLALEAPSHQPSGKLRHWLQKLKTAKKKETAGCLEASAILHIFQVLNDLRCAAQREDCT
Protein: Alcohol acyltransferase 9 (AdAT9) (EC 2.3.1.268) (P0DO25)
Organism: Actinidia deliciosa (Kiwi)
Function: Involved in the biosynthesis of volatile esters which confer kiwifruit flavor. Alcohol acyl transferase that can use a wide range of alcohols as substrate to produce esters. Exhibits acetyl-CoA:alcohol O-acyltransferase activity.
Interaction partners:
Sequence:
MASSVRLVKKPVLVAPVDPTPSTVLSLSSLDSQLFLRFPIEYLLVYASPHGVDRAVTAARVKAALARSLVPYYPLAGRVKTRPDSTGLDVVCQAQGAGLLEAVSDYTASDFQRAPRSVTEWRKLLLVEVFKVVPPLVVQLTWLSDGCVALGVGFSHCVIDGIGSSEFLNLFAELATGRARLSEFQPKPVWDRHLLNSAGRTNLGTHPEFGRVPDLSGFVTRFTQERLSPTSITFDKTWLKELKNIAMSTSQPGEFPYTSFEVLSGHIWRSWARSLNLPAKQVLKLLFSINIRNRVKPSLPAGYYGNAFVLGCAQTSVKDLTEKGLGYCADLVRGAKERVGDEYAREVVESVSWPRRASPDSVGVLIISQWSRLGLDRVDFGLGRPVQVGPICCDRYCLFLPVRDRTESVKVMVAVPTSAVDRYEYFIRSPYS
Protein: Structural maintenance of chromosomes protein 5 (Q59UE8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- DNA repair protein
- Non-structural maintenance of chromosomes element 4
- Non-structural maintenance of chromosomes element 1 homolog
- Smc5-Smc6 complex subunit
- SUMO ligase
- Kleisin alpha
- Condensin complex subunit 2
- Structural maintenance of chromosomes protein
- Condensin complex subunit 1
- SUMO family protein
Sequence:
MSSESNGSASKRRKVLEPSKFRPGFIRKVRVWNFTTYSYTEFNLSPTLNMIIGPNGSGKSTLVASICIGLAGSINLIKRKNLKSMIKTGQEKSSVEITIENYEGHSPIVIKREFTAKESNWTVNNKRATESKIKDIRTKFNIQLDNLCHFLPQERVAEFAGLSPEKLLMETERTLGDGHLLIMHEDLIAKDNESQQLGNKIKDIEGRLAKLHEDRSKLEEEARKLEEYDRKSEEVDNHRLLIPYAKYQDLKNQRTHLKRLRDEAKHKLRTFQANFKPLENDIANAEKSINEESEKYSHLKDSLKSTLNEINQHKSTQKQVTTEISELRANLKSYQTRAEQKKKELEEIKKEIAELQEKQRGLPQVDPEEMQNLSTESTSKRHELRDLEEQFQEVNSQRSDIGRELTHLTEQLRGAEKRLSTKDKLDMLVSDARQNGRSYRLRDEAFDVHKRLRNEPEYEGRYFEAPVISCNVPDINYAAAAEKIIDNNTLFAFTVTNQSDFDFLSKFSQQTNTNTPLRMVNSVVNPTHEYSKHQLREFGFEGYLSDYIVGPKEVLSMLYSTSKIHTIPVSKHQLSSEQVRRLTNVSGNDRLPFTKFVAGDTLYNIQRSKYGSQQAFYITEKIGRSQYFGVQGLSQEAKDAINAEISKFKEKIEQKKRAYEGHRNNIDSFNERLTEIKHYIHDIKRKQSELQEISKRAGQLQTKIELKKEREQKLEKDSKRDYSSKIRMFEQKIDEKYLASGELFASLSNSVLELCEKENQMKLKKLEIIGYKNKKLTAESLLDELGARQEKLKNDYNRYKREYDEIKQSEAFKEIERQNEAYTDEERSRLADLAQVYVENGTFTEATIRSKIDLLEDELSLLTTADRGSIDALKQKLQDIQLAETNLPLLQTEKERLDTRIKGIQEEYEGELTSLVNKISLAFNKRFTKVASDGRVQLAKSERFKDWKLQILVKFRQESELKVLDHQSQSGGERAVSTIFFIMSLQGLTDAPFRIVDEINQGMDPKNEQMAHRYLVHTACQNSKSQYFLVTPKLLTGLYYHPDMVVHCIFTGPYITDNEEKRDNSMGMLDFAV