wanglab/gogpt-training-data huggingface dataset:
Protein: Transcription cofactor vestigial-like protein 4 (Vgl-4) (Q14135)
Organism: Homo sapiens (Human)
Function: May act as a specific coactivator for the mammalian TEFs.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcriptional enhancer factor TEF-3
- Transcriptional enhancer factor TEF-1
- Transcriptional enhancer factor TEF-5
- Interferon regulatory factor 2-binding protein 2
- Transcriptional enhancer factor TEF-4
- Probable E3 ubiquitin-protein ligase IRF2BPL
- Transcriptional coactivator YAP1
- Interferon regulatory factor 2-binding protein 1
- Transcription cofactor vestigial-like protein 1
- WW domain-containing transcription regulator protein 1
Sequence:
METPLDVLSRAASLVHADDEKREAALRGEPRIQTLPVASALSSHRTGPPPISPSKRKFSMEPGDEDLDCDNDHVSKMSRIFNPHLNKTANGDCRRDPRERSRSPIERAVAPTMSLHGSHLYTSLPSLGLEQPLALTKNSLDASRPAGLSPTLTPGERQQNRPSVITCASAGARNCNLSHCPIAHSGCAAPGPASYRRPPSAATTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS
Protein: Tensin-1 (EC 3.1.3.-) (Q04205)
Organism: Gallus gallus (Chicken)
Function: May act as a protein phosphatase and/or a lipid phosphatase. Involved in fibrillar adhesion formation. Plays a role in cell polarization and migration. May be involved in cartilage development and in linking signal transduction pathways to the cytoskeleton.
Subcellular location: Cell surface {ECO:0000250|UniProtKB:Q9HBL0}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q9HBL0}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9HBL0}.
Interaction partners:
- Integrin beta
- Focal adhesion kinase 1
Sequence:
MDFGSVMNQAATPCSPAVNYELPSPGQSITKQVDTPDATRSPRGGQAHRKASRSMSVTAAMESSCELDLVYITERIIAVSYPSTAEEQSFRSNLREVAHMLKSKHGDNYVLFNLSERRHDISKLHPKVLDFGWPDLHTPALEKICSICKAMDTWLNAAAHNVVVLHNKGNRGRLGVVVAAYMHYSNISASADQALDRFAMKRFYEDKVVPVGQPSQKRYIHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTGICITIEPGLLLKGDILLKCYHKKFRSPTRDVIFRVQFHTCAVHDLDIVFGKEDLDEAFRDERFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYENFNIQREDSTEGTWAEPALPGKHLEKEVGHTQGPLDGSLYAKVKKKDSLHGSIGAVNAARLPLSAAPNHVEHTLSVSSDSGNSTASTKTDRTDEPGAPGAPTGHAVLSPEEKRELDRLLVGFGLESAPPMHNHAPGPAPARLPAGPGRHVVPAQVHVNGAGTPLLAERETDILDDELPNQDGHSVGSLGTLSSLDGTTTASEAGFHEAPRVGSLSSLPNGPASYNGAEKMLKEGLYEAEPLSNGAYPYSNQNTLMGHHLRDPLAHLRPSASAQEHLAGYPQRQPASTSPAWLQPPVPQPYLYGYDLPSAHRSQSFPAVGTAKYEANLALPQAPARSTSSREAVQRGLNSWQQQGGSRPPSQLHDGGLESHSPSLSSCSPQPSPLQPMPPHSHSMPEFPRAPSRREIEQSIEALDVLMLDLAPSVHKSQSVPSAATRQDKPAAMLSSLSAQPLSGHYAQPTPQVVQPRSFGTSVGTDPLAKAYSPGPLVPAARSTAEPDYTVHEYRETYTPYSYQPVPEPRSYGSAPASILPLSASYSPAGSQQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRSGEEPLNLEGLVAHRVAGVQSREKSPEESTVPARRRTPSDSHYEKSSPEPGSPRSPTVLSPEVVSTIAANPGGRPKEPHLHSYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVGELEGEAGADSEEEPRSYVESVARTATTGRAGNLPAAQPVGLEVPARNGAFGNSFTVPSPVSTSSPIHSVDGASLRSYPSEGSPHGTVTPPHAVAETAYRSPMVSQTPSAHSSYQTSSPSSFQAGTLGSPYASPDYPDGRAGFQPDPQARQQPQVSVVGVHALPGSPRTLHRTVATNTPPSPGFGRRAANPAVASVPGSPGLGRHTVSPHAPPGSPSLARHQMAAVPPGSPMYGYSSPEERRPTLSRQSSASGYQPPSTPSFPVSPAYYPGTSTPHSSSPDSAAYRQGSPTPQPALPEKRRMSAGERSNSLPNYATVNGKASSPLSSGMSSPSSGSAVAFSHTLPDFSKFSMPDISPETRANVKFVQDTSKYWYKPDISREQAIALLKDREPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDITNELVRHFLIETSPRGVKLKGCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEKKDAASTTNSATDLLKQGAACNVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGSTTDNVCHLFAELDPDQPAAAIVNFVSRVMLGSGQKR
Protein: Cadherin-13 (Truncated cadherin) (T-cad) (T-cadherin) (P33150)
Organism: Gallus gallus (Chicken)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9WTR5}; Lipid-anchor, GPI-anchor {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:Q9WTR5}.
Interaction partners:
- C1q domain-containing protein.
- Adiponectin receptor 2
- Uncharacterized protein.
- Plakoglobin
- Uncharacterized protein.
Sequence:
MQHKTQLTLSFLLSQVLLLACAEDLECTPGFQQKVFYIEQPFEFTEDQPILNLVFDDCKGNNKLNFEVSNPDFKVEHDGSLVALKNVSEAGRALFVHARSEHAEDMAEILIVGADEKHDALKEIFKIEGNLGIPRQKRAILATPILIPENQRPPFPRSVGKVIRSEGTEGAKFRLSGKGVDQDPKGIFRINEISGDVSVTRPLDREAIANYELEVEVTDLSGKIIDGPVRLDISVIDQNDNRPMFKEGPYVGHVMEGSPTGTTVMRMTAFDADDPSTDNALLRYNILKQTPTKPSPNMFYIDPEKGDIVTVVSPVLLDRETMETPKYELVIEAKDMGGHDVGLTGTATATILIDDKNDHPPEFTKKEFQATVKEGVTGVIVNLTVGDRDDPATGAWRAVYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLIPDIAYGPSSTATVQITVEDVNEGPVFHPNPMTVTKQENIPIGSIVLTVNATDPDTLQHQTIRYSVYKDPASWLEINPTNGTVATTAVLDRESPHVQDNKYTALFLAIDSGNPPATGTGTLHITLEDVNDNVPSLYPTLAKVCDDAKDLRVVVLGASDKDLHPNTDPFKFELSKQSGPEKLWRINKLNNTHAQVVLLQNLKKANYNIPISVTDSGKPPLTNNTELKLQVCSCKKSRMDCSASDALHISMTLILLSLFSLFCL
Protein: Mitogenic exotoxin Z (Q99XW1)
Organism: Streptococcus pyogenes serotype M1
Interaction partners:
Sequence:
MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEYSDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKDGDKIAMFSVPFDWNYLSEGKVIAYTYGGMTPYQEEPMSKNIPVNLWINRKQIPVPYNQISTNKTTVTAQEIDLKVRKFLISQHQLYSSGSSYKSGKLVFHTNDNSDKYSLDLFYVGYRDKESIFKVYKDNKSFNIDKIGHLDIEIDS
Protein: Cilia- and flagella-associated protein 70 (Flagellum-associated protein 70) (A8ITV9)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Axoneme-binding protein that acts as a regulatory componement of the outer dynein arm and regulates ciliary motility.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:30158508}. Cell projection, cilium {ECO:0000269|PubMed:15998802}. Note=Localizes at the base of outer dynein arms. {ECO:0000269|PubMed:30158508}.
Interaction partners:
Sequence:
MAPKKKEDKDAPPPEDTNPYGVFVSVTMPSATVVLDVQDDAAAQRETHITLNIPGCHVPWASAHTAPSEGGVYQYSVVKHFRRSGGQDGLLQLINGVLTVTVNDSATNAVLASATVDQLQGFAIGQNTWSTEGLDLVPAAEVPEGVPKARSARLAFASIALQERPLPEGADAAALAAAPPPPEAELPPLLPYSYVSGEAAEKGNMVELVVSGLSPLPPNLQAAADAAGGKLHVTVGLALPGGGPAVAVSLAVAGGRVAAPAFRRELLPPGCLQALQYALEDGLPVVLEVARYVSAEGMADPAFEGYHAAAAAPALAAGLGAAGATEAAAEGLSLTAWAASGAKTCLPPYTAPAGKPKPVEAEVPPAGTCLWEKAGAQLAVSLRFARPVVPAWRPPPPPPRPLLELIPPRDLTPKPPPTTAVDEFKAKVRVIARALAEEYKAVLPPPDASVAAAAAGGGAEGRHKALIFELNRSGKYAQMRDSLKTAVVSLVREKYRKSGSMSPNEMALLYNDLYGSLLAAVHSSLNDLVDAAAARPRAPPPAPVPDKQRLGELLELAAQAEAMGDTDRAELLHQRRLLAKNDAQVWYEYGTYCLRRGGAKRGRAEECFREALALEPAHRGALLALLGCSVAAGRNTDPAYLESAEAAAHRLLDVAGRSSLDAWAALAVVYRAYGEAKRAELASCEQEMARLEKQQLAAAAAAASAGVSPSPSYGEGRAGGNGGGVPATEPSTASAGSVAGSAGELQARSFISLANTLLESLALPAEAALALELAAGLRHWPSVGPDTRTLHALAGALAEQALARAAGGGAASAAAEAMLTPGSSVLSMMRADAGEAVSSVAAEAAWRCRLLVAQLHKARGATDEAIRFYQSFIAITQQHAPSTPPPPPPPPPPPPPPPPQEYIEAARSSGRLAEVPLSAWLELAEAYAARGQARFAADVFLLGASARPGCAVLWRGAGRCFVGAEELGPADMALSEANVLDPEDPEAWGWLALVALREGRAEDAEKALAFGLRCGLGDPGLLLDIAAEYRAAGQRRAEQRVLQEVAVKLMPESCSARLLLARCLVAQRCGAEAAEAVAAARQLAAHEDDEAAVAELEAELRGMA
Protein: TRAF-type zinc finger domain-containing protein 1 (Protein FLN29) (Q3UDK1)
Organism: Mus musculus (Mouse)
Function: Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
Interaction partners:
Sequence:
MAEFRDDQASRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHMAAEHCQVTCKCNKKLEKRQLKQHAETECPLRLAVCQHCDLELSVVKLKEHEDYCGARTELCGSCGRNVLVKELKTHPEVCGRVEEEKRTEAAIPPEAYDEPWSQDRIWIASQLLRQIEALDPPMRLPGRPLQAFEADPFYSRTTSQRSMAAQFPVQNNLFEEQERQERNRSRQSPKDSAENNAHLDFMLALSLQNEGQATSMVEQGFWESVPEADPARAGPTSLGDIKGAADEILLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGVEDPGTIFQNFLQQATSNQFDTLMGLSSSAAVEDSIIIPCEFCGVQLEEEVLFYHQDQCDQRPATANHRAVEGIPAQDSQPENTSAELSRRRVKHQGDLSSGYMDDVKPESVKGPTYSMSPNRTMNNVASCNRLLNLPSGPRSDCQRSPPGVLKLNNSDSQDIRGQMRGSQNGPIASGHAPVIHSIQNLYPENFAPSFPHGSPGRYGAGGRSEGGRSSRVSPAAAGYHSRAAKAKPPKQQGAGDAEEEEE
Protein: Parvalbumin beta 1 (P86431)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
Interaction partners:
Sequence:
ACAHLCKEADLKTALEACKAADSFNFKTFFHTLGFASKXXDDVKKXXXVLDQDASGFLEVEELKLFLQNFCPKXXXLTDAETKAFLKAGDADGDGMLGLDEFAVLVKQ
Protein: Troponin C, skeletal muscle (P02586)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Interaction partners:
Sequence:
MTDQQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ
Protein: Probable G-protein coupled receptor 19 (GPR-NGA) (Q15760)
Organism: Homo sapiens (Human)
Function: Orphan receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Adropin
- Transcription factor ETV6
Sequence:
MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWVFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV
Protein: Tail protein (H9C1B0)
Organism: Pectobacterium phage ZF40 (Bacteriophage ZF40)
Interaction partners:
Sequence:
MTRLFGRVYNLEVTSAEGNKLTCEPPTQVKFLITNMPMNQVATAMIMIYGVSDQYRQLIQKFDETRQRFGTVRLTAGYEESSGEIFTGQINSVEVGRDGVNVYLRLNCWSVIWSDATIGKTWGEKTQAIEILQDVARSFGPPIETVGDFSDLPMFNHGYTLPHTSSRNFLNAMKAAWRYDWLLSDTKTTLIRDGATRPTTYELNSDNGMESYPRWYQKDLEVDARLNHIIQPGDLIKIRSDFWTINYSGMYNAGLNDMSNIQRRTGSFRVLSTTHQGDFWNDDWRTTFRCQWSAA
Protein: Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Q97SU1)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00235}.
Interaction partners:
Sequence:
MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTEMGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLAELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDKPETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK
Protein: GM14286p (Pyruvate dehydrogenase phosphatase, isoform A (EC 3.1.3.16, EC 3.1.3.43)) (Pyruvate dehydrogenase phosphatase, isoform B) (Q9W3Q1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Pyruvate dehydrogenase E1 component subunit alpha
- [Pyruvate dehydrogenase
- FI22513p1
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Sequence:
MFKFVLNDAASYVRSNVREFSLNALRLLPQLPQLSPYDVNLVLRENEFVYNFPVDGVIRSYETNQLGSNWPCEDSRTEASFLHRNGFICGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLREQMKQGADSQSFLKCHNDNVDFVSMIKPMYEASFLKYVNQLLETPQRDVSSELVNAFLQLDEEISQEALTSNDVRTMNVALSGAVACLVHIEGLQMHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQQKVLPMFGVQAMAPNYYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEGDTTLQEISQQLAERKAGLTRKPVDQNAATHLIRHALGGTDYGIEHSKISYYLTLPRDAVRLYRDDITITVIYFNSEHIAKLHSDVDQTEVTAPVA
Protein: Elongation factor 1-alpha (Q38C34)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- GST N-terminal domain-containing protein
- Elongation factor 2
- Eukaryotic peptide chain release factor subunit 1
- Small ribosomal subunit protein uS5
- Translation elongation factor 1-beta, putative
- Translation elongation factor 1-beta, putative
- Translation elongation factor 1-beta, putative
- 60S ribosomal protein L4
- 60S ribosomal protein L5, putative
- Elongation factor 2
Sequence:
MITGTSQADAAILIIASAQGEFEAGISKDGQTREHALLAFTLGVKQMVVCCNKMDDKTVNYGQERYDEIVKEVSAYIKKVGYNVEKVRFVPISGWQGDNMIEKSEKMPWYKGPTLLEALDMLEPPVRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVMKPGDVVTFAPANVTTEVKSIEMHHEQLAEATPGDNVGFNVKNVSVKDIRRGNVCGNTKNDPPKEAADFTAQVIILNHPGQIGNGYAPVLDCHTSHIACKFAEIESKIDRRSGKELEKAPKSIKSGDAAIVRMVPQKPMCVEVFNDYAPLGRFAVRDMRQTVAVGIIKAVTKKDGSGGKVTKAAVKASKK
Protein: Osteoclast stimulatory transmembrane protein (OC-STAMP) (Q9D611)
Organism: Mus musculus (Mouse)
Function: Probable cell surface receptor that plays a role in cellular fusion and cell differentiation. Cooperates with DCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Involved in osteoclast bone resorption. Promotes osteoclast differentiation and may play a role in the multinucleated osteoclast maturation.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Dendritic cell-specific transmembrane protein
- Cathepsin K
- Nuclear factor of activated T-cells, cytoplasmic 1
- V-type proton ATPase subunit d 2
- Tumor necrosis factor ligand superfamily member 11
Sequence:
MRTIRAATEHLFGLGWKFWRLGICKAVVPLQAAWKAFSQPVPASCNELLTQLLLCVSLASLIAGLAHHWLVSLQLYPLGPPALVTSLCGLFVFLSLGLVPPIRCLFVLSVPTLGSKQGRRLLLSYSAANLAVAVVPNVLGNVRAAGQVLSCVTEGSLESLLNTTYQLRQAARELGPASRAGSRSLTFEVEGKGSAFRLHMHTITQEILEDFSGLEFLARAALGTQRVVTGLFLLGLLGESAWYLHRYLTDLRFDNIYATRQLVRQLAQAGATHLLTSPPPWLLQTAQPKLSREELLSCLLRLGLLALLLVATAVTVASDYGAFLLAQAAVAWAQKLPTVPITLTVKYDASYKVLDFILFVLNQPPVESVFASMQRSFQWELRFTPHDCHLPQAQPPRVTAALAAGALQLLAGATLVLQAYAWRLRHTIAASFFPDQEARRLSHLQARLQRRHNQSDHLNKQPGTMATRESRKPGQGTRTLESQGPQAHDSLGPPYDLE
Protein: XICL (Q91603)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAFHIALQEEMIVASPAALPRLSLGTGRGACRNLFGPIDHDELRSELKRQLKEIQASDCQRWNFDFESGTPLKGTFCWEPVETKDVPSFYSPSRSLAANTTPQSRQQQPLLVSRQPEPREEAPVDTVRNVPNPPCAKENAEKIIKRCQGVKGPTKASANTSTQRRKREITTPITDYFPKRKKILSAKPDATKGVHLLCPLEQTPRKKIR
Protein: Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) (O15068)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
Subcellular location: [Isoform 5]: Cytoplasm {ECO:0000269|PubMed:15157669}. Cell membrane {ECO:0000269|PubMed:15157669}; Peripheral membrane protein {ECO:0000269|PubMed:15157669}; Cytoplasmic side {ECO:0000269|PubMed:15157669}.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm {ECO:0000269|PubMed:15157669}. Endomembrane system {ECO:0000269|PubMed:15157669}. Note=Interaction with membranes enriched in phosphoinositides is mediated by the CRAL-TRIO domain. {ECO:0000269|PubMed:15157669}.; SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q64096}. Cell membrane {ECO:0000250|UniProtKB:Q64096}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q64096}; Cytoplasmic side {ECO:0000250|UniProtKB:Q64096}.
Interaction partners:
- Cell division control protein 42 homolog
- Transforming protein RhoA
- Ras-related C3 botulinum toxin substrate 1
Sequence:
MFDCWRFILCKRPGSNSYSSPQRPNEAKKEETDHQIDVSDVIRLVQDTPEATAMATDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLSVRLGPSGSAQCLSSSGKAHVPRAHP
Protein: Pcdhgc3 protein (Q4KMN6)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MVAEARSSGLVSPWRTVGVLLLLAALTEASTIIHYEILEERERGFPVGNVVTDLGLDLGSLSARRLRVVSGASRRFFEVKVQVSDINDNPPQSSQSSYDVYVEENNLPGVPILNLSVWDPDAPPNARLSFFLLEPGAETGLVSRYFTINRDNGVLTTLVPLDYEDQREFQLTAHINDGGTPVLATNISVNVFVTDRNDNAPQVLYPRPGQSSVEMLPRGTAAGHVVSRVVGWDADAGHNAWLSYSLLGAPNQSLFAVGLHTGQISTARPIQDTDSPRQILTVLISDSGEPLLSTTATLTVSVTEESPEARAEFPSGSAPREQNKNLTFYLLLSLILVSVGFAVTVLGVIIFKVYKWKRSRDLYRAPVSSLYRTPGPSLHADAVRGGLMPPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Protein: FCS-Like Zinc finger 12 (F4IE21)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
Interaction partners:
- FCS-Like Zinc finger 16
- FCS-Like Zinc finger 11
- Protein INCREASED RESISTANCE TO MYZUS PERSICAE 1
- FCS-Like Zinc finger 10
- SNF1-related protein kinase catalytic subunit alpha KIN10
Sequence:
MLSSNPMTWKLSHMVVPGKNSTISPDYFTASQTSPLDMMKFPSPGSSKRYDNGGGIGLGIVAALEKSSIGINPVCHTGAGSKGFDLARYSKRFQFAAGIDLSDSEEYTCVTTRDGLTKVYYKEEEFEFGHNLLNGDQRWRKPIEIAEESPAKERRVLRDCPDFLTSCCLCKKKLQGKDIYMYKGDEGFCSKECRSLKIMEDSLKEQHKLTSVEVLTGEEIASPGIFLI
Protein: Aryl hydrocarbon receptor (Q9YGV3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSAGIGTYAVKKRKKPVQKIPKPPPPDGVKSNPSKRHRDRLNSELDKLTNLLPFSEDVRARLDKLSVLRLSVGYLKVKSFFNATIKKTGGNGWLNDRSGTFGGNGQTASSLDGVNFSEGELLLQALNGFVLVVTAEGYVFYSSPTIQDYLGFHQSDVVHHSVFELIHTDDRAMFRRQLHFALNPSSDSADGSEAMQSSSDITRDMVNYNPQHIPPENSSFLERSFCCRFRCLLDNSSGFLALNFQGRLKYLHGQNKLAEDGTLAHPQLALFIIATPLQPPSILEIRSKTLLFQTKHKLDFTPMGIDTRGKVVLGYTEIELCMRGSGYQFIHAADMMYCADNHIRMIKTGESGLTVFRLLSKGGTWIWVQANARLVYKAGRPDFIIARQRALTNEEGEEHLRQRKLQLPFNCATGEGVLYEVGPTLDVAEIQNQSKGQKMLNPPSLDPDSLLGSMLKQDHSLYSQNNDPNSQFTIDKAFGDSHALLNVPGNTWQPSTPNTVPGIKEEAVVKDMLETLQQIIEVGNNCNSLEDFNLDRMELKEWENTLCRMNYNNDMEINEIITEDIFSYVEDVLFKENGIQPLKDLGPFSEMSEGLSELELQNNLAANQEFSCQAGVHGGSPGQGGFIGMNIQEGMDTSSPGRGTVKLSHMGPQMLPGNNFIQSFGLDQTTQKMAGNSNILFRPSLAMQQSQQPNQVNLGLQGVVQENGIVPCGQRNLLTGNQPHPNTMTLPLQSPLVQGTSTQPMGFRNQNSLPQQPSISQNPQWVPSSNSVVDNRMNSCAHNVSGPQDAGLHSGPFANLQGQFSLHTQNAANAGPPGWQQSQPTPQGVPTSFSGGHQPGFISQVTDFQRGTLNQMMPHTNGQGIGSGFLPKESASAIYPQQGDFINNSPHKTSTSCMFMNNAQPSVNGMQYGSADLVSGMSSCQGTKGLLTQSPTQASCYFQRGPSETIVGTAVIPQEDNNISPMACQLPLGLPPDNIISQQYLSCNTQTQVANRPLKETEMFHFPMLTNGTTYFPDNNQSNCCDY
Protein: LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein (A0A1D8PEJ0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Histidine-rich glycoprotein-like
Sequence:
MIKKPLATMPTLNSRRIRLVLTLGLLLLCLIKTIHLKLTSPLNQAYLEYQALQLQQLSNFNPKNNLIELFDYLNTWHLNNTLKDHQHSNPKYQVDKVSTIGDSHGVYFHWDDWVDLSLGNKKLDKVRQRNSKGQDHSDDDEDEDQLEVDDNECDASLLHYANVNAHRLESLETKHIRGRCQLYCSFPIPQRIIATTDNLFIEIPVIGKKRLGIQVSTTNNDKKFTTTTKLVSTMENLQNNFRQHYHNQQNLHTSEEPQLLIRNITRLQPKIDNLSVKDFVFNIDSEIEKLQIANLTTENGLNQTDLSRLNFYQQANALVDKTDRHFKYAWVFTDIIQGYTHHIAYPFFNRYISDRERQSVLHHMIRVWFQLMETYGYTSWINYGNLLGWKFNGLNMPWDTDIDVQMPIVELDRLAMNLNQTLIIENPRFGNARYWLEISPSYIRQGNGKNHIDARFIDIHSGLYIDITGLSTEEMIPEPATTTATTTKGEVNQSNEDENDVAASSSSIAVHCKNWNWHKLNELLPLKQAFFEGSSVYIPNNVSTILLNKYGDDALSDYKFHNHIYYPDISMWINNDICQLERNTGVIGGINLGVNIKNWNPTTNTNNNNNEGEEKSPIESSCDLKYIQDEYNIIKESVMRHQYLENLNLEDKQHQHEQQQRQKEEMISRLNNLPIFRKDPWDYYYDINHNLVTNDRWYVKIEEVAV
Protein: Protochlorophyllide reductase A, chloroplastic (PCR A) (EC 1.3.1.33) (NADPH-protochlorophyllide oxidoreductase A) (POR A) (P13653)
Organism: Hordeum vulgare (Barley)
Function: Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
Subcellular location: Plastid, chloroplast.
Interaction partners:
Sequence:
MALQLLPSTLSVPKKGSSMGAVAVKDTAAFLGVSSKAKKASLAVRTQVATAPSPVTTSPGSTASSPSGKKTLRQGVVVITGASSGLGLAAAKALAETGKWHVVMACRDFLKASKAAKAAGMADGSYTVMHLDLASLDSVRQFVDAFRRAEMPLDVLVCNAAIYRPTARTPTFTADGHEMSVGVNHLGHFLLARLLMEDLQKSDYPSRRMVIVGSITGNSNTLAGNVPPKASLGDLRGLAGGLSGASGSAMIDGDESFDGAKAYKDSKVCNMLTMQEFHRRYHEETGITFSSLYPGCIATTGLFREHIPLFRTLFPPFQKFVTKGFVSEAESGKRLAQVVAEPVLTKSGVYWSWNKDSASFENQLSQEASDPEKARKVWELSEKLVGLA
Protein: Trafficking protein particle complex subunit (Q20100)
Organism: Caenorhabditis elegans
Subcellular location: Endoplasmic reticulum {ECO:0000256|RuleBase:RU366065}. Golgi apparatus, cis-Golgi network {ECO:0000256|RuleBase:RU366065}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit 6B
- Trafficking protein particle complex subunit 3 homolog
- Trafficking protein particle complex subunit 2-like protein
- Trafficking protein particle complex subunit 8
- Trafficking protein particle complex subunit 10
- Trafficking protein particle complex subunit 9
- Trafficking protein particle complex subunit 11 domain-containing protein
- Probable trafficking protein particle complex subunit 2
Sequence:
MSNHIQHLFIINRAGSLIYSWEARTETPEVEKTYEWPIDVHLEEVDQKAVVVFGEKDGIKLRYYVKSVNGETVSGTRLQLGAQQVNVLEYLQEEDHYPVTVKFAAPTVSTNEKIILSSMFHSLFTIAVQLSPCQKSSGVEVLETTQFKLFCLQSRTGVKFVVITSAASNIAADSLLSKMYELYTDFALKNPFYSIDMPIRAQKFDEAIKTLLERAEKNNGAVTF
Protein: CUGBP Elav-like family member 6 (CELF-6) (Bruno-like protein 6) (CUG-BP- and ETR-3-like factor 6) (RNA-binding protein BRUNOL-6) (Q7TN33)
Organism: Mus musculus (Mouse)
Function: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MAAAPGGSAPPAGPSPRLAFSTADSGGGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIQGLHGSRTMTGASSSLVVKLADTDRERALRRMQQMAGQLGAFHPAPLPLGACGAYTTAILQHQAALLAAAQGPGLGQVAAVAAQMQHVAAFSLVAAPLLPAAANTSPGGNGPGALPGLPAPMGVNGFGSLTPQSNGQPGSDTLYNNGVSPYPAAYPSAYAPASTAFSQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY