wanglab/gogpt-training-data huggingface dataset:
Protein: Histone deacetylase complex subunit SAP18 (A0A384ME24)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR037637}. Nucleus speckle {ECO:0000256|PIRNR:PIRNR037637}.
Interaction partners:
Sequence:
MAVESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFTDVKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPPPSGRMRPY
Protein: Mitochondrial RNA binding protein (D6XL11)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFRRLTQYTGVVGAVRTIVVFSQQHHILESNQKARSSPSNVWIEDWEAESYGLTPEPGAVSTQLLLDKPLELYNFDQLLSPPEVMEAPKHSSYSSRKVYGEKLQFELNDRAQKHGFHSKWWLTRTQAVKNALTFKNNARSSIILSKSSLRLYHSSQLVGGEALMTHPVSGGSRKLYSRKGDAYQVLCEHIRQNAFNSGLYFTRRQLEFFKLAVQPSQAPVMMDVSSGERFLIFNVEQLEDPEVALRTLDRSPVSIPTFLLSGEPMQHEGVKRLPRFKSNYWLSGRDAELYQWPIKESEKKRGVTLKNEGSASLQVELFNVEQLANPEEAFAKAGLFVQ
Protein: tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)] (EC 1.3.1.88) (mRNA-dihydrouridine synthase dus1) (EC 1.3.1.-) (tRNA-dihydrouridine synthase 1) (Q9HGN6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}. Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Putative tRNA pseudouridine synthase C16C4.06c
- D-arabinono-1,4-lactone oxidase
- tRNA
- U3 small nucleolar RNA-associated protein 21 homolog
- tRNA
- tRNA
Sequence:
MASKKLHGRDFYNKIGRPKRILAPMVDQSELPWRILARRSGADLCYSPMFHSRLFGESEDYRNKVFSTRTIPEERPLIIQFCGNDPEIMLKAAKIAAPYCDAVDVNLGCPQGIAKKGKYGSFLQENWNLIESIITKLHTELSIPVTAKIRIFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADWEQIQMLRKNLPSETVLFANGNILHAQDIDRCIKYTGVDGVLSAEGSLYNPRIFLPPSSPLMTLYPRIDDMCEEYLNIIREFKLESDYSSLSAIKGHLFKLMRPLLSIHTDIRSKLAQGCTPRDFETFPPVVAMLRKRLLECEEKGEINEDKDVKESVKDSMGYPVIPWWRVQPYIRPLEVPLVTKRKPVEVTADEGPVKKKVNASVA
Protein: M-factor (P34069)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: M-factor is a mating pheromone produced by M-type mating cells. All three mfm genes contribute to the production of M-factor.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- M-factor
- M-factor
Sequence:
MDSIATNTHSSSIVNAYNNNPTDVVKTQNIKNYTPKVPYMCVIA
Protein: N-alpha-acetyltransferase 30 (EC 2.3.1.256) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit) (Q147X3)
Organism: Homo sapiens (Human)
Function: Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19398576, ECO:0000269|PubMed:25732826}. Nucleus {ECO:0000269|PubMed:25732826}.
Interaction partners:
- N-alpha-acetyltransferase 38, NatC auxiliary subunit
- N-alpha-acetyltransferase 35, NatC auxiliary subunit
- N-alpha-acetyltransferase 15, NatA auxiliary subunit
- N-alpha-acetyltransferase 16, NatA auxiliary subunit
- N-alpha-acetyltransferase 20
- N-alpha-acetyltransferase 10
- N-alpha-acetyltransferase 11
- N-alpha-acetyltransferase 25, NatB auxiliary subunit
- N-alpha-acetyltransferase 50
- N-alpha-acetyltransferase 40
Sequence:
MAEVPPGPSSLLPPPAPPAPAAVEPRCPFPAGAALACCSEDEEDDEEHEGGGSRSPAGGESATVAAKGHPCLRCPQPPQEQQQLNGLISPELRHLRAAASLKSKVLSVAEVAATTATPDGGPRATATKGAGVHSGERPPHSLSSNARTAVPSPVEAAAASDPAAARNGLAEGTEQEEEEEDEQVRLLSSSLTADCSLRSPSGREVEPGEDRTIRYVRYESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR
Protein: Testis-specific chromodomain protein Y 1 (EC 2.3.1.48) (Q9Y6F8)
Organism: Homo sapiens (Human)
Function: Has histone acetyltransferase activity, with a preference for histone H4.
Subcellular location: Nucleus {ECO:0000269|PubMed:18450745}.
Interaction partners:
- Testis-specific basic protein Y 2
- Deleted in azoospermia protein 1
- Deleted in azoospermia protein 2
- Deleted in azoospermia 4.
- Testis-specific basic protein Y 1
- PTPN13-like protein, Y-linked
- Histone H3.3
- Histone H3.1
- Histone H3.2
- Histone H3.3C
Sequence:
MASQEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNRKLFAASKNVRRKAASILSDTKNMEIINSTIETLAPDSPFDHKTVSGFQKLEKLDPIAADQQDTVVFKVTEGKLLRDPLSRPGAEQTGIQNKTQIHPLMSQMSGSVTASMATGSATRKGIVVLIDPLAANGTTDMHTSVPRVKGGQRNITDDSRDQPFIKKMHFTIRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSKLVLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTFTQEVMIQIKELASYNPIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENKIDEF
Protein: Flagellar brake protein YcgR (Cyclic di-GMP binding protein YcgR) (Q8ZP19)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Overexpression of this gene decreases swimming and swarming motility; those cells that are motile turn predominantly counterclockwise. The D-118 mutant is still able to bind FliM but no longer affects motility upon overexpression. Binds 1 c-di-GMP dimer per subunit.
Subcellular location: Bacterial flagellum basal body {ECO:0000269|PubMed:20346719}. Note=Localization lost in FliM mutants E-155 or E-160.
Interaction partners:
- Flagellar motor switch protein FliM
- Flagellar motor switch protein FliG
- Anti-FlhC
- Motility protein B
- Anti-FlhC
- Cellulose synthase catalytic subunit
- RNA polymerase sigma factor FliA
- Chemotaxis signal transduction protein
- Negative regulator of flagellin synthesis
- Motility protein A
Sequence:
MSGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKILAVDPEKLIVDYGSQEYENSAVLRAGQVAIIAETQGAKVEFTLPQLVTGEYQRLPAFITPLPSSLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIPDGLIEGARFSQVELNMGQWGIFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQRIIFSLEREARERANKVRE
Protein: G-patch domain and KOW motifs-containing protein (G-patch domain-containing protein 5) (Protein MOS2 homolog) (Protein T54) (Q92917)
Organism: Homo sapiens (Human)
Function: RNA-binding protein involved in pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000269|PubMed:21880142, ECO:0000269|PubMed:25296192}.
Interaction partners:
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
- RNA-binding protein 10
- BUD13 homolog
- E3 ubiquitin-protein ligase RNF113A
- Spliceosome-associated protein CWC27 homolog
- Pre-mRNA-splicing factor CWC22 homolog
- RING-type E3 ubiquitin-protein ligase PPIL2
- Pre-mRNA-processing-splicing factor 8
- Armadillo repeat-containing protein 7
Sequence:
MADSKEGVLPLTAASTAPISFGFTRTSARRRLADSGDGAGPSPEEKDFLKTVEGRELQSVKPQEAPKELVIPLIQNGHRRQPPARPPGPSTDTGALADGVVSQAVKELIAESKKSLEERENAGVDPTLAIPMIQKGCTPSGEGADSEPRAETVPEEANYEAVPVEAYGLAMLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKGLGLGANLTEAQALTPTGPSRMPRPDEEQEKDKEDQPQGLVPGGAVVVLSGPHRGLYGKVEGLDPDNVRAMVRLAVGSRVVTVSEYYLRPVSQQEFDKNTLDLRQQNGTASSRKTLWNQELYIQQDNSERKRKHLPDRQDGPAAKSEKAAPRSQHWLHRDLRVRFVDNMYKGGQYYNTKMIIEDVLSPDTCVCRTDEGRVLEGLREDMLETLVPKAEGDRVMVVLGPQTGRVGHLLSRDRARSRALVQLPRENQVVELHYDAICQYMGPSDTDDD
Protein: 4-chlorobenzoyl coenzyme A dehalogenase (4-CBA-CoA dehalogenase) (4-CBCoA dehalogenase) (4-chlorobenzoyl-CoA dehalogenase) (EC 3.8.1.7) (A5JTM5)
Organism: Pseudomonas sp. (strain CBS-3)
Function: Dehalogenates 4-chlorobenzoyl-CoA, 4-iodobenzoyl-CoA and 4-bromobenzoyl-CoA, but not 4-fluorobenzoyl-CoA. Inactive towards crotonyl-CoA, alpha-methylcrotonyl-CoA and beta-methylcrotonyl-CoA.
Interaction partners:
Sequence:
MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRIGALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDDFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHPHFMPCLTEFLDGHRADRPQVELPAGV
Protein: BZIP domain-containing protein (A7SNT7)
Organism: Nematostella vectensis (Starlet sea anemone)
Interaction partners:
- BZIP domain-containing protein
Sequence:
MESSAYERFDIPLTFAKCGLLERQSVSVASSCNGWPAASKVDVKRELKTCIKTKFEEMGIQLPKVEYKRPPTPQPRPPEKPEVVEQRRRQNKFAAMKSRKKRTERINRLRQKTRKYEESIRKHGMVVKKLREEAEQLKQYLISHNCCKNKKASMGKATTSTYNPCFNVSWLPQHQQQQKQMGETSFDRELNNIFSNLY
Protein: Telomerase-binding protein EST1A (EC 3.1.-.-) (Ever shorter telomeres 1A) (hEST1A) (Nonsense mediated mRNA decay factor SMG6) (Smg-6 homolog) (hSmg5/7a) (Q86US8)
Organism: Homo sapiens (Human)
Function: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12676087}. Chromosome, telomere {ECO:0000305|PubMed:12699629}. Cytoplasm, cytosol {ECO:0000269|PubMed:12676087}. Note=Particularly enriched in the nucleolus. {ECO:0000269|PubMed:12676087}.
Interaction partners:
- Regulator of nonsense transcripts 1
- Nonsense-mediated mRNA decay factor SMG5
- Nonsense-mediated mRNA decay factor SMG7
- Regulator of nonsense transcripts 3A
- Telomerase reverse transcriptase
- Serine/threonine-protein kinase SMG1
- Regulator of nonsense transcripts 2
- Nonsense-mediated mRNA decay factor SMG9
- Nonsense-mediated mRNA decay factor SMG8
- Polyadenylate-binding protein 1
Sequence:
MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLRNKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDPENNRGQESFPRTAGQEDRSLKIIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEVLNQVEQLRVEEDECRGNVAKEEVANKPDRAEIEKSPGGGRVGAAKGEKGKRMGKGEGVRETHDDPARGRPGSAKRYSRSDKRRNRYRTRSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSSTDSLDEDRIDEPDGLGPRRSSERKRHLERNWSGRGEGEQKNSAKEYRGTLRVTFDAEAMNKESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVNSAGSPESAPLGPRLLFGSGSKGSRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTDDEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYPGPYYPGYPTPSGQYVCSPLPTSTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLSRDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKDPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKYALISAQRCMICQGDIARYREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKSTFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPASKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
Protein: Phosphoinositide-3-kinase-interacting protein 1 (Calcineurin-regulated kringle domain-containing protein) (Kringle domain-containing protein HGFL) (Q7TMJ8)
Organism: Mus musculus (Mouse)
Function: Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q96FE7}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Sequence:
MLLAWVHTFLLSNMLLAEAYGSGGCFWDNGHLYREDQPSPAPGLRCLNWLAAQGSRESLTEPSPGNHNYCRNPDQDPRGPWCYISSETGVPEKRPCEDVSCPETTSQAPPPSSAMELEEKSGAPGDKEAQVFPPANALPARSEAAEVQPVIGISQLVRMNSKEKKDLGTLGYVLGITMMVIILAIGAGIIVGYTYKRGKDLKEQHEKKACEREMQRITLPLSAFTNPTCETVDENTIIVHSNQTPADVQEGSTLLTGQAGTPGA
Protein: Restriction of telomere capping protein 1 (SEH-associated protein 2) (Q08281)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. May be involved in a process influencing telomere capping.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:21454883}; Peripheral membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:21454883}.
Interaction partners:
- SEH-associated protein 4
- Nucleoporin SEH1
- Protein transport protein SEC13
- Vacuolar membrane-associated protein IML1
- Nitrogen permease regulator 3
- Maintenance of telomere capping protein 5
- Nitrogen permease regulator 2
- GTP-binding protein GTR1
- GTP-binding protein GTR2
- Mitochondrial inner membrane protease subunit 1
Sequence:
MSLSPHVENASIPKGSTPIPKNRNVSSIGKGEFLGSSSSNNSSFRMNHYSNSGQPSVLDSIRRPNLTPTFSYSNGVYMPESHRTSSFNDSYLPYDKNPYAKTTGSMSNKSNMKIKTKKNAINTNTRKSSGLIYTTKVDKELSSIDKVNDPNINGLVCAGKTHLGLYKFSPSDRSIKCVHDFITPNSNTSTRGTTSLLPKLSKRTRQNKFSTIADVKTGFNNYKNCIAVCNNSTAISIYDLNKSSSIDNPLITSLCEHTRSINSFDFNMVESNLIISGGQDSCVKIWDLRSNKSKSSNRSDISINTASDSIRDVKWMPGYNFASKNDQGSSTYGNLKSGYKFASIHDSGYLLKFDLRQPAQYEKKLNAHTGPGLCLNWHPNQEYIATGGRDGKCCLWFVGDNANAAENTVLNYGNSPSLHAPNTSLNNSGSLAFPKLTINTGYPVTKLKFKPAYSSNIYNSLLGISSMGDEAEVRIYSLARKYIPKHVLLSETPSLGLVWWDENLIFNIDKGTRINGWDINKEPTVLENLSKNTTTWRDLDGNGLLSVDQEIGSYEVVEPELQPTSSTTCKKHPGTIKNPKNGNPENQGIIGGIKKGFSHTGLTSFTPERPPTLKAGPTFSTKSLTLASGASSFNSSSASLTSLTPQTENREEIAIEPPCIITLDIPQIFNNIRLTKIAHSRKKNVISESSSMKNSPVEKFKYLARQLKFSYIREHNVSDSADTAYKNDIENIDVVKNATETHGDNTTTTNNNDDGDDDDDDDDDDKIIESHLLKKYNFPENNTWATLMNEKVNNKKSKRNSSSSREFDEKDVRSSISSISASRQSHDRARKIDKNVEAELQEKIQTLVDLISIATHNASVYLSIDDLTNFKIWILIRDSLLWDLKWMTSSQISSDNASNMDANESSDFEAGENLKTGKEFPEEDGAGTSGAESLVEERPQAFRANSDEPSDAEKKPVSKLKEQLKNTEIIPYAQPNEDSDEVLTKLKELQNQRLESRTKMGETVSDDVIIEEDEHEHQEEEQPHDSPTKSAQFHASPIAKSIPILQKREHRKSFIDTFMLHSPNGYNGDTDIGNEDDNISPRFTYNSVSPRSKVSSLQSYATTTSQLETFKKLSSHTAPIIGSPRHAPSRPDSIGREQLSSSLTKKLAKCKKIIADPPWDTKKLIKQLYNQATETGNVVLTVNILFLFQTIYQITEIDIAKDAIAHFLLLLHRYELFGIAADVLKYCPFEDIMGSEGDQSSIRLFCERCGELITNESSKEKLRAEAQQTGNKKIMDKFGYWYCDSCKKKNTSCVLCERPLKKLTMVILPCGHEGHFQCIQEWFLDENEQECPGGCPGVAFI
Protein: LSDAT_euk domain-containing protein (Q20766)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Putative nudix hydrolase 6
- Anion transporter SULP-4
Sequence:
MINETKTNGISEETISDNEEEEEEEERHRTSSFLRLLNAPRNSMCNANTVHSISSFRSDHLSRKSTHKFLDNPNLFAIELTEKLSPPWIENTFEKRECIRFAALPKDPERCGCGRPLSAHTPASTFFSTLPVHLLEKEQQTWTIANNTQTSTTDAFGTIVFQGGAHAHKAQYVRLSYDSEPLDVMYLMEKVWGLEAPRLVITVHGGMSNFELEERLGRLFRKGMLKAAQTTGAWIITSGLDSGVVRHVAKALDEAGISARMRSQIVTIGIAPWGVIKRKERLIRQNEHVYYDVHSLSVNANVGILNDRHSYFLLADNGTVGRFGADLHLRQNLENHIATFGCNGRKVPVVCTLLEGGISSINAIHDYVTMKPDIPAIVCDGSGRAADIISFAARYINSDGTFAAEVGEKLRNLIKMVFPETDQEEMFRKITECVIRDDLLRIFRYGQEEEEDVDFVILSTVLQKQNLPPDEQLALTLSWNRVDLAKSCLFSNGRKWSSDVLEKAMNDALYWDRVDFVECLLENGVSMKNFLSINRLENLYNMDDINSAHSVRNWMENFDSMDPHTYLTIPMIGQVVEKLMGNAFQLYYTSRSFKGKYDRYKRINQSSYFHRKRKIVQKELFKKKSDDQINDNEEEDFSFAYPFNDLLIWAVLTSRHGMAECMWVHGEDAMAKCLLAIRLYKATAKIAEDEYLDVEEAKRLFDNAVKCREDAIELLDQCYRADHDRTLRLLRMELPHWGNNNCLSLAVLANTKTFLAHPCCQILLAELWHGSLKVRSGSNVRVLTALICPPAILFMAYKPKHSKTARLLSEETPEQLPYPRESITSTTSNRYRYSKGPEEQKETLLEKGSYTKKVTIISSRKNSGVASVYGSASSMMFKREPQLNKFERFRAFYSSPITKFWSWCIAFLIFLTTQTCILLLETSLKPSKYEWITFIYTVTLSVEHIRKLMTSEGSRINEKVKVFYAKWYNIWTSAALLFFLVGYGFRLVPMYRHSWGRVLLSFSNVLFYMKIFEYLSVHPLLGPYIQMAAKMVWSMCYICVLLLVPLMAFGVNRQALTEPNVKDWHWLLVRNIFYKPYFMLYGEVYAGEIDTCGDEGIRCFPGYFIPPLLMVIFLLVANILLLNLLIAIFNNIYNDSIEKSKEIWLFQRYQQLMEYHDSPFLPPPFSIFAHVYHFIDYLYNLRRPDTKRFRSEHSIKLSVTEDEMKRIQDFEEDCIDTLTRIRKLKLNTKEPLSVTDLTELTCQRVHDLMQENFLLKSRVYDIETKIDHISNSSDEVVQILKNKKLSQNFAASSLSLPDTSIEVPKITKTLIDCHLSPVSIEDRLATRSPLLANLQRDHTLRKYDDANFQPGKLQRRARLHSSSCSISQDMKEMKTSMSSRNLKREDSGEITTSSHGGYDSDVSGPD
Protein: Gap junction protein (Q8JHW1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, gap junction {ECO:0000256|ARBA:ARBA00004610}. Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}.
Interaction partners:
Sequence:
MGDWNLLGSILEEVHIHSTIVGKIWLTILFIFRMLVLGVAAEDVWDDEQSEFVCNTEQPGCKNVCYDQAFPISLIRYWVLQIIFVSSPSLVYMGHALYRLRALEKERHKKKVQLKVELEESEALEEHKRIEKELRKLEEQKKVRKAPLRGSLLRTYVFHILTRSVVEVGFIVGQYMLYGIGLTPLYKCERDPCPNSVDCFVSRPTEKNIFMIFMLVISGVSLFLNLLEIFHLGVKKIKQTIYGSMYSDDDSICRSKKNSMVQQVCFLTNSSPQKQLHLTHTSLAMAPDGQMVPLPIYMQTAGHVVSNINPNGSVQPLRQDRLPSQPEIQVLQQLGIKERRSIPDNRLQSCSSEDSGPKGSEPPKYSQQPRASFRASHIEIPAALRKHSRVSQCKDFSEESDSVESGNYPTARKASFMSRGLSESPSESAASKSGSDTEANRITQGESPAMTPPPAAGRRMSMVRKF
Protein: Golgi apparatus membrane protein TVP38 (TLG2-vesicle protein of 38 kDa) (P36164)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Golgi membrane protein involved in vesicular trafficking and spindle migration.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16107716, ECO:0000269|PubMed:17178117}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16107716, ECO:0000269|PubMed:17178117}.
Interaction partners:
- Golgi apparatus membrane protein TVP15
- Golgi apparatus membrane protein TVP18
- Golgi apparatus membrane protein TVP23
- Mitotic spindle-associated protein SHE1
- t-SNARE affecting a late Golgi compartment protein 2
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Glycine cleavage system H protein, mitochondrial
- Protein GVP36
Sequence:
MSQSYEAGNANMGQGEDDEFDGYFEDFDNDIMPNSNNGQRVGTNAGLSFNDEVNVNDDDFLDIYNMSPRERLMHNIRKNVQKLQFYFYSLRLWQQIIIVLLGIMLMIMGILLLVFHNAILHKVVVTSNDLREKMSTHFILMVLIFFVAFPPMIGYSLLSTTTGLIYGVSFEGWVTLALGSVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQENNSYWILALLRLCPFPYSLTNGAIAGVYGISVRNFSIANIITTPKLFIYLFIGSRVKSLAESESTGSRVFDLVSIIITLLILSLTAWLLYFKTKKRYLELQNRDRQVSTDQLPELSFEV
Protein: Phytoene desaturase (B2CPV2)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
PEDWREISYFKKLEKLVGVPVINVHIWFDRKLKNTYDHLLFSRSPLLSVYADMSVTCKEYYNPNQSMLELVFAPAEEWIACSDSEIIDATMKELAKLFPDEISADQSKA
Protein: Seven TM Receptor (Q18570)
Organism: Caenorhabditis elegans
Interaction partners:
- Serpentine receptor class gamma-8
- Seven TM Receptor
- G-protein coupled receptors family 1 profile domain-containing protein
Sequence:
MDNFELIVFLTQRVCTILAFLIHFPLTLLILYKSPSSFGAYKYLLTYISIFELVYAVLDVLVSPQLYTHKSAFMLVLDSNKTFLPFWTLYPIDLLFCGMLGCSMAIFTINFIYRYLVMKGSELLKSFESSKLFIWIASPMVYSAIWMFITEMTLQGNPDTDKLLEDTFLKKQKISLSEVVYIGPNYYPEEGVIDWIPIIGMISLTLMIFVSVYSIIYFAVNSYVAMNKLVLTSVNSQRYKANQTELLNALVIQAIIPFALMHFPASIVFITPFFNCGNQTFARIFSVTVALYPVLDPLPTIFVVKCYRKAVIKYLNILFSFCSNQPTIVTEQHSSTSYKCPAITA
Protein: Calcitonin gene-related peptide 1 (CGRP1) (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I) (Q99JA0)
Organism: Mus musculus (Mouse)
Function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P06881}.
Interaction partners:
Sequence:
MGFLKFSPFLVVSILLLYQACSLQAVPLRSILESSPGMATLSEEEVRLLAALVQDYMQMKARELEQEEEQEAEGSSVTAQKRSCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAFGRRRRDLQA
Protein: Quinol oxidase subunit 2 (EC 1.10.3.-) (Cytochrome aa(3) subunit 2) (Quinol oxidase polypeptide II) (Q81HT3)
Organism: Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
Function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Cytochrome aa3 quinol oxidase polypeptide III.
- Cytochrome aa3 quinol oxidase polypeptide I
- Cytochrome c oxidase polypeptide III.
- Cytochrome aa3 quinol oxidase polypeptide IV.
- Cytochrome c oxidase polypeptide I
- Protoheme IX farnesyltransferase
- Menaquinol-cytochrome c reductase cytochrome c subunit
- Cytochrome c oxidase polypeptide IVB.
- Cytochrome c oxidase polypeptide II
- Menaquinol-cytochrome c reductase cytochrome b subunit.
Sequence:
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDYEPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPKESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPAGVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEVQETAPKLTEAKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
Protein: Small ribosomal subunit protein eS25y (40S ribosomal protein S25-2) (Q9SIK2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Large ribosomal subunit protein uL4z
- Small ribosomal subunit protein uS15y
- Large ribosomal subunit protein eL31x
- Small ribosomal subunit protein eS28x
- Small ribosomal subunit protein eS21y
- Small ribosomal subunit protein eS12y
- Small ribosomal subunit protein eS28z/eS28y
- Small ribosomal subunit protein eS1z
Sequence:
MAPKKDKVPPPSSKPAKSGGGKQKKKKWSKGKQKEKVNNMVLFDQGTYDKLLTEAPKFKLITPSILSDRMRINGSLARRAIRELMAKGLIRMVSAHSSQQIYTRATNT
Protein: Drebrin-like protein (Actin-binding protein 1) (Dabp1) (Actin-binding protein E) (Q557J6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Actin-binding adapter protein. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin. Controls pseudopodium number and motility in early stages of chemotactic aggregation.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16449327}. Cell projection, pseudopodium {ECO:0000269|PubMed:16449327}.
Interaction partners:
- Myosin-K heavy chain
- Adenylyl cyclase-associated protein
Sequence:
MASLDISDPDITKYIKLVQDGNPANRWIVFSYVPKSNNKIKFCDSGSGDLKELREELDDSSIRFAYIRFVINNMPKFVYIPWCGDGVNGPIKGAFSGHAIEFSKSFKPIHHQVNARSEEDIDEKAITAALNKATGASYDSGSKVQGATKGTFIPQSVSQGREAATKSNAEVKNVINKNDYNKIQESAEYWKQNQANKSEPAKPTRPEYNLSTERDDYWKQQQAEKQKQQQQQQQQQASRVNAPPPSRTVGNKFQEQVSKPTETAPPQPRPAPSKGSVLNRFPAATQQQQEPPAPSRPAAPVPSRVNKPAAPVQPVYQEPVHEEPQYEEPQYEEEQQQQYEEQPTEEQQYYQEEPQQQYEEQPTEEQQYYQEEQQQYEEQPTEEQQYYQEEQQQYEQPTEDQQYYQEEQQQYEQPAEEQYDQSGYLQAKALYDYNGENDGDLSFREGDIITILDQSDPDGWWQGSLPTGEQGFFPSNFVQQL
Protein: Adenylyl cyclase-associated protein 1 (CAP 1) (Q01518)
Organism: Homo sapiens (Human)
Function: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Cofilin-1
- Resistin
- Actin, alpha skeletal muscle
- Resistin-like beta
- Twinfilin-2
- Twinfilin-1
- Profilin-1
- Actin-related protein 3
- Actin, cytoplasmic 1
- Profilin-4
Sequence:
MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSCPPPPPPCPPPPPVSTISCSYESASRSSLFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG