wanglab/gogpt-training-data huggingface dataset:
Protein: Phospholipid-transporting ATPase (EC 7.6.2.1) (D4A3X6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}.
Interaction partners:
- Cell cycle control protein 50A
- Cell cycle control protein
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
Sequence:
MNPQACTSGRLCYPVMMPLACSRTMRDLTQRGPVRSSAGYKKAEDEMSRATSVGDQLEAPARIIYLNQSHLNKFCDNRISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLVIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQGMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGRIECEGPNRHLYDFTGTLHLDGKSSVALGPDQILLRGTQLRNTQWVFGVVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSVGALFWNGSHGGKSWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIENDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREQSSDDFCRMTSCPSDSCDFNDPRLLKNIEDEHPTAPCIQEFLTLLAVCHTVVPEKDGDEIIYQASSPDEAALVKGAKKLGFVFTGRTPYSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRMPSGQLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASIILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNAEGFNTKVFWGHCINALVHSLILFWVPMKALEHDTPLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLIWLVFFGVYSTFWPTIPIAPDMKGQATMVLSSAHFWLGLLLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVMGKAMLRDSNGKRWAAPGVPSCPLLSHISPPWLVFKGSVVGSVSGILITC
Protein: MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1) (Q9D7G9)
Organism: Mus musculus (Mouse)
Function: Involved in the maintenance of the spindle integrity during the cytostatic factor (CSF) arrest of oocytes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12011110}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:12011110}. Note=Colocalizes with the spindle at discrete sites during the second meiotic division.
Interaction partners:
Sequence:
MYPFIPPARLLPGSPAPFLPSGPSCPQPSGPYPGPAVRVPGPTRSYVSTNVPFPELPRPNSAPTDPVGPLGTQGSMSSGPWAPGMGGQHPNVPYLFPESSPTPPLPVSGAPPVAWVTVPPGAWEPPAQYPTPEASYPSPGLQPSPNNPYPLPPGPSAASPGPGSLHRMNEIPGGSPSDSSNPESTLESTGQKKHLKLDNKSIKRRRSKKKSKRVTWGDIKTLTHKAESLGKQQGHNTTDPKMMLLCLMTMLHVNSQHESEGSK
Protein: Fibrillarin (M0R2B0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGP
Protein: Large ribosomal subunit protein uL22m (39S ribosomal protein L22, mitochondrial) (L22mt) (MRP-L22) (Q9VXB5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9NWU5}.
Interaction partners:
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein uL11m
- Small ribosomal subunit protein bS6m
- Ribosomal protein
- Large ribosomal subunit protein bL9m
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein bL19m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein bS16m
Sequence:
MHKVIRQMSQLRLQAPQGAALLRSADSSSISPAISPVSPPALQSKSLHTAASAGMLCAKWNKYNYGPRKWLEYNKTVHPPQETDEEPRNAYVCHMRSNIKYSPDKMWYIAAFVRGMSVDEALKQLNFVLKKGATDVKETILEAQQIAVERHNVEYKSNLWIAESFVGKGRVFKGVRRHARGRFGKVEYKHCHYFVRLEEGEPPQHYYQEPQTPEQQYESWMEQMRSRKIINSL
Protein: Atlastin GTPase 1 (Atlastin-1) (B8A6H1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Spastin
- Receptor expression-enhancing protein.
- Magnesium transporter NIPA1
- Spartin
- Receptor expression-enhancing protein 2
- Reticulon
- Reticulon
- Reticulon
- Reticulon.
- Reticulon
Sequence:
MARDKKDRDSWGSFVDKNVYDWSSEEEEADGRARPVQVLVVKDDHTFELDEAALSKILLSEEVRDREVVAISVAGAFRKGKSFLMDFMLRYMYSQASEKWLGDAEEPLTGFSWRGGSERETTGIQIWSEVFLVDKPDGSKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSMQVYNISQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFPYGQEGGMKFLEKRLKISENQHEELQNVRKHIHSCFTNISCFLMPHPGLKVATNPHFDGRLREIDQEFINNLQVLVPCLLRPKNLDVKEINGSKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAKDLYNRKMEVVSGGDRPFLAPSELQARHLEIREEALALFRSVKKMGGEEFSRRYLLQLETEIDELFVQYIKHNDSKNIFHAARTPATLFVVIFVMYVAAGITGFVGVDVIASVCNMVLGFALITLCTWAYIRYSGEYRELGAVIDQVAGALWDQALYKLYSVAANHRQLYNHAFPGHQSDQQPEQDKKRN
Protein: Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1) (Q08BJ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
- Gamma-aminobutyric acid type A receptor subunit gamma2
- Gamma-aminobutyric acid receptor subunit beta-1
- Gamma-aminobutyric acid type A receptor gamma1 subunit
- Gamma-aminobutyric acid type A receptor beta3 subunit
- Gamma-aminobutyric acid type A receptor beta2 subunit a
- Gamma-aminobutyric acid type A receptor beta2 subunit
- Gamma-aminobutyric acid receptor subunit beta-4 isoform X1
- Gamma-aminobutyric acid
- GABA
- Gamma-aminobutyric acid
Sequence:
MMWGGRGAAWLWIWACLLVTNALAGKSSSQNADEQKDNTTVFTRILDSLLDGYDNRLRPGLGERVTEVKTDIFVTSIGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMAVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEEGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYVWTRGAAQSVVVADDGSRLNQYDLMGQSVDSGVVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKQKKKKESLLKKNNTYTAATATAFAPNIARDPGLATIAKSAPPPPTEPKEEPKPKPPEAKKTFNSVSKIDRIARIAFPLLFGTFNLVYWATYLNKKPKLQGMNLQPH
Protein: E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220) (Q5VTB9)
Organism: Homo sapiens (Human)
Function: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling. Plays a critical role in the regulation of nuclear lamina.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:33964137}. Nucleus {ECO:0000269|PubMed:33964137}.
Interaction partners:
- Zinc finger C4H2 domain-containing protein
Sequence:
MDLHRAAFKMENSSYLPNPLASPALMVLASTAEASRDASIPCQQPRPFGVPVSVDKDVHIPFTNGSYTFASMYHRQGGVPGTFANRDFPPSLLHLHPQFAPPNLDCTPISMLNHSGVGAFRPFASTEDRESYQSAFTPAKRLKNCHDTESPHLRFSDADGKEYDFGTQLPSSSPGSLKVDDTGKKIFAVSGLISDREASSSPEDRNDRCKKKAAALFDSQAPICPICQVLLRPSELQEHMEQELEQLAQLPSSKNSLLKDAMAPGTPKSLLLSASIKREGESPTASPHSSATDDLHHSDRYQTFLRVRANRQTRLNARIGKMKRRKQDEGQREGSCMAEDDAVDIEHENNNRFEEYEWCGQKRIRATTLLEGGFRGSGFIMCSGKENPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEPGEAKEREALRGAVLNGGPPSTRITPEFSKWASDEMPSTSNGESSKQEAMQKTCKNSDIEKITEDSAVTTFEALKARVRELERQLSRGDRYKCLICMDSYSMPLTSIQCWHVHCEECWLRTLGAKKLCPQCNTITAPGDLRRIYL
Protein: Uncharacterized protein, isoform O (M9PF71)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNKVEFKNKNKDQGPCARVRKIRPINMGGNVEQRPWTPTVRIGKIAAETTNPGPATVQLPTLIGSKVPDSKKKAAPSYSFGHKLGGKYDTSGPGPAQYNVTGMRAKGRDYPRAATLQSRPKELTRFSNPGPGEYDVVPAAKAVIDATPKYTFGQRPVALKTFQIPAPNSYCPEKVTQSKKNAPRYTFGRRTKIEHDQGTPAPGAYCPEKVKLNKTPEFSFGIKHHEQRPDYTPAPGTYKPEQVVLEHIPAYSFGLKTKHIQVSDTPAPGAYSPEKSRLHSAPAYSIAGKASQDVVDCTPAPGAYEPEKCVLSRTPAFSFGHRAELAKSSDTPAPGTYNPEKVRLDHTPAFTLSGRPETRSVSETPAPGSYAPEKYRNDRTPAFTFGGKHEQRLESSTPAPGDYCPEKVRHDHNPAFSFAGRHDLHKPSDTPAPGAYDTEKVRQDHNPAFSFAGRHDLHKPSETPAPGAYSPEKVRQDHNPAFSMAGKHSQKVTSDSPAPGDYCPEKVRLDHTPAYSFGVKSDPKVENNTPAPGDYHPEKVRQDHNPAYSFAGRHDLQKPDNTPAPGAYFPEKVRLDHNPAFSMAGKYDAKVTNDTPAPGDYSPEKVRQDTNPAYSFAGRHDLHKPSETPAPGAYSPEKVRLDHNPAFTMAGKHDQKILNGTPAPGDYSPEKCRLDHTPAYSFGGKNDPKVENNTPAPGDYHPEKVRLDHNPAYSFAGRHDLQKPSDTPAPGAYSPEKVRQDHNPAFSMAGKPVEKLTNGTPAPGDYSPEKVRLNHTPAYTFGGKNDPKVENNTPAPGDYHPEKVRQDHNPAFSFAGRHDLHKPNDTPAPGAYCPEKVRQDHNPAFSMAGKYTQKVANDTPAPGDYSPEKVRLDHTPAYTFGGKNDPKVESNTPAPGDYHPEKVRQDHNPAFSFAGRHNLQKPSDTPAPGAYSPEKVRQDHNPAFTMAGKHDPKVSNDTPAPGDYSPEKVRLDYTPSFTFAGKNNPKVENDTPAPGDYHPEKVRQDHNPAFSFAGRHDLHKPSDTPAPGAYSPEKVRQDHNPAFSMAGKYIEKITNGTPAPGDYCPEKVRLDHTPAFTFGGKNDPKVENNTPAPGDYHPEKVRQDHVPAFSFAGRHDLHKPNETPAPGAYSPEKVRQDHNPAFTMAGKHDPKVTHDTPAPGDYHPEKVRLDHNPAFSFAGRHDLHKPSETPAPGDYFPEKVRQDFNPAFTFAGKHDPRSLSESPAPGDYSPEKVRLDHAPAFSFGGKHDPKTEHLHPAPCDYAPEKVRLDHTPAYTIAGRPAADHVSQTPAPCDYHPEQCQVDSTPAFTFGMRLGRERISDTPAPSAYEPEKHSLHSTPAYSFGTKSDIRVTTDAPVRNNAECTTTTTNHTNNNAGSSTTTTTTTTTTTKTFINGVEQPELQKKETTKQVNGTHKELKSAPQAPLSNGNIVSNGNHSKMVSTTTRIQEVAHGQKESGNLKVVASGKSDASATKAAAVSHQTVVQADGAIVTSGQSSRMQTVKYAVEASSVQEKIISS
Protein: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit) (Q641Y2)
Organism: Rattus norvegicus (Rat)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I. Essential for the assembly of complex I (By similarity). Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction. Plays an important role in carotid body sensing of hypoxia (By similarity). Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:30922174}; Peripheral membrane protein {ECO:0000305|PubMed:30922174}; Matrix side {ECO:0000269|PubMed:30922174}.
Interaction partners:
- NADH dehydrogenase Fe-S protein 7, isoform CRA_d
- NADH dehydrogenase 1 beta subcomplex subunit 3
- Acyl carrier protein
- NADH dehydrogenase 1 subunit C1, mitochondrial
- NADH:ubiquinone oxidoreductase complex assembly factor 2
- NADH-ubiquinone oxidoreductase chain 3
- NADH-ubiquinone oxidoreductase chain 2
- NADH dehydrogenase 1 alpha subcomplex subunit 11
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
Sequence:
MAALRAVCSLRGVGAQVLRAGSGIRLPSQPSRGARRWQPDIEWAEQFSGAVMYPSKETAHWKPPPWNDVDVLKEKVVTNVTLNFGPQHPAAHGVLRLVLELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRILNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYEFSKNFSLRIDEVEEMLTNNRIWRNRTVDIGVVSAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEIDR
Protein: Elongation of very long chain fatty acids protein 2 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL2) (ELOVL fatty acid elongase 2) (ELOVL FA elongase 2) (Very long chain 3-ketoacyl-CoA synthase 2) (Very long chain 3-oxoacyl-CoA synthase 2) (G1MWP1)
Organism: Meleagris gallopavo (Wild turkey)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|HAMAP-Rule:MF_03202}; Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_03202}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAYRNQPLYGEKLEEHIEHLKAFDQEVNAFVDYMFGPRDSRVRGWLLLDSYLPTFFLTVAYLLSIWLGNKFMKNRQPFSLRAHLIVYNLGITLLSLYMLIELILATWEGGYNLQCQNLHSAGEADIRVAKVLWWYYFSKVIEFADTIFFVLRKKSSQITFLHVYHHATMFNIWWCVLNWIPCGQSFFGPTLNSFIHVLMYSYYGLSVIPSMRKYLWWKKYLTQAQLIQFLLTIVHTLSAAVKPCGFPFGCLMFQSSYMATLVILFINFYIKTYQKAPSRTAAKETPVTTEVKNGFHKNYFAASNGFLNNKKAQ
Protein: AT5g43460/MWF20_18 (HR-like lesion-inducing protein-like protein) (Nicotiana lesion-inducing like) (Q9LSW5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Pentatricopeptide repeat-containing protein At5g15300
- F-box/kelch-repeat protein SKIP6
- Thioredoxin superfamily protein
- Duplicated homeodomain-like superfamily protein
- Homeodomain-like transcriptional regulator
- At2g32380
- T12C22.21 protein
- Fasciclin-like arabinogalactan protein 7
- Phosphoinositide phospholipase C 9
- Leucine-rich repeat extensin-like protein 4
Sequence:
MGFFSFLGRVLFASLFILSAWQMFNDGGPAAKELAPKLDLVKAHLSSRLGVTLPKIEVRQVVATIIALKGVGGLLFVIGNTFGAYLLASYLVVFGPILYDFYNYGPQERHFSLLLTEFLQSVALFGALLFFIGMKNSTPAKKNLKKRTPKPKAA
Protein: Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3) (Q9QXV1)
Organism: Mus musculus (Mouse)
Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:16537902}. Chromosome {ECO:0000269|PubMed:16537902}. Note=Localizes to the inactivated X chromosome in females. {ECO:0000269|PubMed:16537902}.
Interaction partners:
- E3 ubiquitin-protein ligase RING1
- Polycomb complex protein BMI-1
- E3 ubiquitin-protein ligase RING2
- Polyhomeotic-like protein 3
- Chromobox protein homolog 2
- Polycomb group RING finger protein 2
- E3 SUMO-protein ligase CBX4
- Chromobox protein homolog 7
- Polycomb group RING finger protein 1
- Polyhomeotic-like protein 2
Sequence:
MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSTRGIRIPYPGRSPQDLASTSRAREGLRNTGLPPPGSSTSTCRADPPRDRDRERDRGTSRVDDKPSSPGDSSKKRGPKPRKEPLDPSQRPLGEPSAGLGEYLKGRKLDETSSGTGKFPAGHSVIQLARRQDSDLVQYGVTSPSSAEASSKLAVDTFPARVIKHRAAFLEAKGQGALDPGGARVRHSSGTPASVGSLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR
Protein: 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12) (Protein purple) (Sepiapterin synthase A) (P48611)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for pigment and biopterin synthesis.
Interaction partners:
- GTP cyclohydrolase 1
- Sepiapterin reductase
- RE21057p
- BcDNA.GH10614
- LD24696p
- FI19917p1
- NADP-dependent oxidoreductase domain-containing protein
- Uncharacterized protein, isoform A
- Pyrimidodiazepine synthase
- AT18092p
Sequence:
MSQQPVAFLTRRETFSACHRLHSPQLSDAENLEVFGKCNNFHGHGHNYTVEITVRGPIDRRTGMVLNITELKEAIETVIMKRLDHKNLDKDVEYFANTPSTTENLAVYIWDNIRLQLKKPELLYEVKIHETPKNIISYRGPYPLNGIYNPINKRIAHDSCTNISSDSD
Protein: Possible thioredoxin protein (Thiol-disulfide interchange protein) (O06392)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell envelope {ECO:0000256|ARBA:ARBA00004196}.
Interaction partners:
- Possible cytochrome C-type biogenesis protein CcdA
- Possible cytochrome C-type biogenesis protein CcsA
- Uncharacterized protein Rv0525
- Glutamate-1-semialdehyde 2,1-aminomutase
- Probable conserved transmembrane protein
- Possible membrane-anchored thioredoxin-like protein
- Possible conserved membrane or secreted protein
- Soluble secreted antigen MPT53
- Alkyl hydroperoxide reductase C
- Probable conserved integral membrane protein
Sequence:
MQSRATRRSGALTMRRLVIAAAVSALLLTGCSGRDAVAQGGTFEFVSPGGKTDIFYDPPASRGRPGPLSGPELADPARSVSLDDFPGQVVVVNVWGQWCGPCRAEVSQLQRVYDATRGAGVSFLGIDVRDNNRQAPQDFINDRHVTYPSIYDPAMRTLIAFGGKYPTSVIPSTLVLDRQHRVAAVFLRELLAADLQPVVERVAEEEPSGRAPVGAQ
Protein: Rpgr protein (B1WC72)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Centrosomal protein 290
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
- Protein fantom
- Nephrocystin 4
- Intraflagellar transport 88
- Nephrocystin-1
- IQ calmodulin-binding motif-containing protein 1
- E3 SUMO-protein ligase RanBP2
- Spermatogenesis-associated protein 7 homolog
- Ran-specific GTPase-activating protein
Sequence:
MPRGSRWGTGGLGQYLRPNRVAPAVFPKQAQIPFAAFGMAEPESLVPDTGAVFTFGKTKFAENIPSKFWFKNDVPICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIGFFTPSDIIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLKNKSNVCIPHEVTVGKPISWISCGYYHSAFVTTDGELYTFGEPENGKLGLPNQLLINHRSPQRVLGIPDKVIQVACGGGHTVVLTEKVVYAFGLGQFGQLGLGTFLFETSEPKIIDRIKDQKISHISCGENHTALMTDIGLMYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLKFTVQLIACGGCHMLVFATPRLGTIDETEFEEVYEPYMSTGSLSINDLSPGSSLNRSLSARLRRRERERPSCSASMVGTLPPLEGTSASTSASYFSPSSIPFRLSVNNYPEKSTSDSTEPLDSDYFEDKMNKETETENSSAVDLENFGETIDILNMIPQLSESVKPEAEGMDEQISVPNVEDTVEEEGKKEKETVEEGSLPEDALPETEGSETVVPADEKPAEMVKEENSASLLQRNLREYNENPKGHMYDRVKSSSSEILGGNEPTSKDIKKAKKPFSPLHFRFPSLIGCH
Protein: Homeobox-leucine zipper protein HAT1 (Homeodomain-leucine zipper protein HAT1) (HD-ZIP protein 1) (P46600)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- BZIP transcription factor, putative
- Endosomal targeting BRO1-like domain-containing protein
- Cation/H
- Topless-related protein 3
- At1g73390
- Protein disulfide-isomerase 5-3
Sequence:
MMMGKEDLGLSLSLGFAQNHPLQLNLKPTSSPMSNLQMFPWNQTLVSSSDQQKQQFLRKIDVNSLPTTVDLEEETGVSSPNSTISSTVSGKRRSTEREGTSGGGCGDDLDITLDRSSSRGTSDEEEDYGGETCRKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTKLKQTEVDCEYLKRCVEKLTEENRRLEKEAAELRALKLSPRLYGQMSPPTTLLMCPSCERVAGPSSSNHNQRSVSLSPWLQMAHGSTFDVMRPRS
Protein: Protein SENSITIVE TO PROTON RHIZOTOXICITY 2 (Zinc finger protein STOP2) (Q0WT24)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor. Together with STOP1, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation.
Subcellular location: Nucleus {ECO:0000269|PubMed:23935008}.
Interaction partners:
- Aluminum-activated malate transporter 1
- Protein ALUMINUM SENSITIVE 3
- Protein DETOXIFICATION 42
- Polygalacturonase inhibitor 1
- At1g12090/T28K15.14
- At2g41380
- C2H2 and C2HC zinc fingers superfamily protein
- C2H2-like zinc finger protein
- C2H2-like zinc finger protein
- Plant intracellular Ras-group-related LRR protein 8
Sequence:
MHIHMMNRDEHIAKKVEGSISSFSGETSTSSKQIYVNPVTTTGTKSMEDDDVSLSLLYNLSTLHEKVHQIQSLVSFYMVSTNNINQSSGSTSLAVANIGSLVQEIITAASSMLYTCQQLQIGSNNNNNDIDNDQTVDAMVLEFSRQETDPGHDFVQESTNLFGVQERGQISFPDQNLDWYNTETINPKKDKHRSKPSSGSYDILELDVADLLAKYTHYCQICGKGFKRDANLRMHMRAHGDEYKTREALISPTSQDKKGGYSLKKHYYSCPQHGCRWNQRHEKFQPLKSVICAKNHYKRSHCPKMYMCRRCSVKHFSVLSDLRTHEKHCGDIKWVCSCGTKFSRKDKLMSHVSLFLGHVPAHGSSKPPTITLK
Protein: Phosphohistidine phosphatase SixA (EC 3.1.3.-) (RX6) (P76502)
Organism: Escherichia coli (strain K12)
Function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His-Asp phosphorelay.
Interaction partners:
- Hypoxanthine phosphoribosyltransferase
- Aerobic respiration control sensor protein ArcB
- Protein Syd
- Anti-sigma-E factor RseA
Sequence:
MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVEIERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVASVLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGNGTFNWQMSPCNLKMAKAI
Protein: Schlafen4 (Q9Z0I4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
GILHLPHDYLDFMQYNDYFFVFVKPWKPNQRGPGIATWKTNLYKRIFSFSVELKAADAVQFLKSRPSSHGKTVCNETLNECLSLFNRDWLAYEETFCFTKSTHAEVKLTPKEKISPKEKILELLPQTVSAFANTDGGYLFIGLDGKTQQIIGFEAEKSDLVLLESEIEKCIQQLPVTHFCEEKEKIKYTCKFIEVHKSGAVCAYVCAIRVEKFCCAVFAAEPESWHVEGSCVKRFTTEEWVKRQMDATAVMPGKVICSPEALCMKPFSQHEGYEQLVRTELGSLRKGTLVVSKSWALDLGLQEKQEVIWDVLHISQGSLLTLHVFVQGDENLEGNSSLLGKLGAELKGYYKQIALTLKQTLVNHCGYTAKIGIIVKITYLGHKTMCLYDSSAKICYPQIYYLTTKAVKDLEKALAEILGSYESFYSLPRRNWDSFMSAFLNVGSYIVYFSRNVLTHIRI
Protein: Probable carboxylesterase 5 (AtCXE5) (EC 3.1.1.1) (Q9FX94)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Carboxylesterase acting on esters with varying acyl chain length.
Interaction partners:
- S-formylglutathione hydrolase
Sequence:
MESEIASEFLPFCRIYKDGRVERLIGTDTIPASLDPTYDVVSKDVIYSPENNLSVRLFLPHKSTKLTAGNKLPLLIYIHGGAWIIESPFSPLYHNYLTEVVKSANCLAVSVQYRRAPEDPVPAAYEDVWSAIQWIFAHSNGSGPVDWINKHADFGKVFLGGDSAGGNISHHMAMKAGKEKKLDLKIKGIAVVHPAFWGTDPVDEYDVQDKETRSGIAEIWEKIASPNSVNGTDDPLFNVNGSGSDFSGLGCDKVLVAVAGKDVFVRQGLAYAAKLEKCEWEGTVEVVEEEGEDHVFHLQNPKSDKALKFLKKFVEFIIG
Protein: Probable aquaporin SIP1-2 (Small basic intrinsic protein 1-2) (AtSIP1;2) (Q9FK43)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Water channel required to facilitate the transport of water across cell membrane.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative aquaporin NIP4-1
- Probable aquaporin TIP5-1
- Probable aquaporin NIP5-1
- Probable aquaporin TIP2-2
- Probable aquaporin PIP2-8
- Probable aquaporin PIP2-4
- Aquaporin NIP6-1
- Probable aquaporin NIP7-1
- Aquaporin NIP1-2
- Probable aquaporin NIP4-2
Sequence:
MSAVKSALGDMVITFLWVILSATFGIQTAAIVSAVGFHGITWAPLVISTLVVFVSISIFTVIGNVLGGASFNPCGNAAFYTAGVSSDSLFSLAIRSPAQAIGAAGGAITIMEMIPEKYKTRIGGKPSLQFGAHNGAISEVVLSFSVTFLVLLIILRGPRKLLAKTFLLALATVSVFVVGSKFTRPFMNPAIAFGWAYIYKSHNTWDHFYVYWISSYTGAILSAMLFRIIFPAPPLVQKKQKKA
Protein: Alpha-tubulin N-acetyltransferase 1 (Alpha-TAT) (Alpha-TAT1) (TAT) (EC 2.3.1.108) (Acetyltransferase mec-17 homolog) (Q5SQI0)
Organism: Homo sapiens (Human)
Function: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Membrane, clathrin-coated pit {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Cell junction, focal adhesion {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Cell projection, axon {ECO:0000255|HAMAP-Rule:MF_03130}. Cytoplasm, cytoskeleton {ECO:0000255|HAMAP-Rule:MF_03130}. Cytoplasm, cytoskeleton, spindle {ECO:0000255|HAMAP-Rule:MF_03130}.
Interaction partners:
- Protein deacetylase HDAC6
- NAD-dependent protein deacetylase sirtuin-2
Sequence:
MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTRGTPPGLVAQSCCYSRHGGVNSSSPNTGNQDSKQGEQETKNRSASEEQALSQDGSGEKPMHTAPPQAPAPPAQSWTVGGDILNARFIRNLQERRSTRPW
Protein: Large ribosomal subunit protein eL38z/eL38y (60S ribosomal protein L38) (O22860)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL39y
- Large ribosomal subunit protein eL29z
- Large ribosomal subunit protein eL24y
- Large ribosomal subunit protein eL28z
- Small ribosomal subunit protein eS28x
- Small ribosomal subunit protein eS24y
- Large ribosomal subunit protein eL27z
- Large ribosomal subunit protein eL24z
- Small ribosomal subunit protein uS14z/uS14y/uS14x
Sequence:
MPKQIHEIKDFLLTARRKDARSVKIKRSKDIVKFKVRCSRYLYTLCVFDQEKADKLKQSLPPGLSVQDL