wanglab/gogpt-training-data huggingface dataset:
Protein: HLA class II histocompatibility antigen, DO alpha chain (MHC DN-alpha) (MHC DZ alpha) (MHC class II antigen DOA) (P06340)
Organism: Homo sapiens (Human)
Function: Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
Subcellular location: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
Interaction partners:
- HLA class II histocompatibility antigen, DM alpha chain
- HLA class II histocompatibility antigen, DM beta chain
- HLA class II histocompatibility antigen, DO beta chain
- HLA class I histocompatibility antigen, B alpha chain
- HLA class II histocompatibility antigen, DP beta 1 chain beta chain)
- HLA class II histocompatibility antigen, DP alpha 1 chain
- HLA class II histocompatibility antigen, DR alpha chain
- HLA class II histocompatibility antigen gamma chain
- HLA class I histocompatibility antigen, A alpha chain
- HLA class I histocompatibility antigen, C alpha chain
Sequence:
MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFVPSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR
Protein: LD28067p (Phosphatidylinositol 3-kinase 68D, isoform A (EC 2.7.1.137, EC 2.7.1.154)) (Phosphatidylinositol 3-kinase 68D, isoform C) (Phosphatidylinositol 3-kinase 68D, isoform D) (Q7K3H0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- phosphatidylinositol-3,5-bisphosphate 3-phosphatase
- Pi3K21B, isoform B
- Lateral signaling target protein 2 homolog
- EG:86E4.5 protein
- phosphatidylinositol-3,4-bisphosphate 4-phosphatase
- Putative 1-phosphatidylinositol 3-phosphate 5-kinase
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- phosphatidylinositol-3,5-bisphosphate 3-phosphatase
- Phosphatidylinositol 5-phosphate 4-kinase, isoform A
- Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform E
Sequence:
MSNQAHIDYDKQFQDDLAKATALSLEQHALDDYRRNKKYGSGYQQSSTVAGRDYQAAQRSQSLHQPRRHSEVHQVAISPENAERSRTPPAQGTDNDLICFASPTSKQPESSSPFGKLIEDLQRMQPTNPQSALVPMGPVASASIPPQYGFPPHQQRPTAAQPTPYGMVAGGVVGGPAYGDLQLVPYQPAAQQQRPLNSEELQRLYSMPAQMAVVPVPQPNAYMYYPGAVVTPYTAPIVPGSAAFMPPQYPAQGYGFGGAYTHMDLRRPQSQPAPQQTAPTTSHHHSQPSNHSTSSPAEANGVAFPARRQVPSTVGVSSSSHTGNNGHSSVPRRGNDLIDLNHEDYSRVSVLEAFDPLLNDNTGNDTASDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNRWDKTVATVSPNVGLIGWRQDFLSQPSTSSSQYGVAPPEESLKLAENGSGTISPPPPLPPRNQQCYESNQAAMPVSRPPQSSVLTDSYTSSIPANVVLDRRKTCTRLYELISDQRTDDPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMMDTSIKVIVHPALNTLQSTVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQVKGTVTDYAVKPIGLLEWLAPTSRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTERDDEHDADLLPEHLLPNEVVPIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCSGVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVVLRPRSMLEQIKVKCNELRDAVQELVELYANVFRVAFSVKTPDYSTTPIPISCVSKPIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWLTFDQHPICTLPREARLTFVLYGKQAASEGEPNADQNGERRQVTTELGWCSIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGRIEFPEHQEVPKPAPHYDFASLDANLQEELLDTAELGYTGATERREVFWEKRLYLQSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEWISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPDDPHNSIGAAMVDQEYDESQVTQVRYYRRNKMMLRALMAICGEKMLQRFMYQHRMCQKLTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSNTLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPTGYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCAGYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRDRTPFVLTSDMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLAHMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQMRFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPTHLFRSYREFTEFHQKLCMHFPLVKLHSLPAGVHVGRSNIKSVAEKRLPLIQRFLKSLFDASEEIAHSELVYTFFHPLLRDQQEAKLGMPKIKEVKQQPSRDNPHEIGQIRLSLQYQRGVLTVMIHHAKGLPMLQGGQEPNTYVKCYLKPDPKKETKRKTKVVRKTCVPSFMETLEYRMPLNIIQERRLQVTVWSHDTLQENELLGGFDMDLSKYDLRQELVDWYRLGAVSRN
Protein: Major heat shock 70 kDa protein Bb (Heat shock protein 70Bb) (HSP70-87C1) (Q9BIS2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYSGPTVEEVD
Protein: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (A2BG80)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Protein phosphatase 2
- Protein phosphatase 2, regulatory subunit A, beta a
- Serine/threonine-protein phosphatase 2A activator
- Serine/threonine protein phosphatase 2A regulatory subunit
- Extra spindle pole bodies-like 1, separase.
- NRDE-2, necessary for RNA interference, domain-containing
- Serine/threonine-protein kinase CHK1
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Sequence:
MAGAGGGGNDVQWCFSQVKGAIDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQETENKSQPQCRSEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDASTITTLRVPVFRPMDLMVEASPRRVFANAHTYHINSISVNSDNETYLSADDLRINLWHLEITDRSFNIVDIKPANMEDLTEVITAAEFHPHQCNTFVYSSSKGTIRLCDMRASALCDKHSKLFEEPEDPSNRSFFSEIISSISDVKFSHNGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGNDSVVMTGSYNNFFRMLDRTQRRDVTLEASRESCKPRQVLKPRRVCAGGKRKKDEISVDSLDFNKKILHTAWHPQENIIAVATTNNLYIFQEKVN
Protein: Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1) (P22777)
Organism: Mus musculus (Mouse)
Function: Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair (By similarity). Involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P05121}.
Interaction partners:
- Tissue-type plasminogen activator
- Vitronectin
- Urokinase-type plasminogen activator
- Urokinase plasminogen activator surface receptor
- Vitamin K-dependent protein C
- Plasminogen activator inhibitor 2, macrophage
- Plasminogen
- Type-1 angiotensin II receptor A
- Prolow-density lipoprotein receptor-related protein 1
- Type-1 angiotensin II receptor B
Sequence:
MQMSSALACLILGLVLVSGKGFTLPLRESHTAHQATDFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNEKGTAHALRQLSKELMGPWNKNEISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVDFSEVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQRDTLSMFIAAPFEKDVHLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFSATLADFTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVIDRSFLFVVRHNPTETILFMGQVMEP
Protein: Probable galacturonosyltransferase-like 3 (EC 2.4.1.-) (Q0V7R1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in pectin and/or xylans biosynthesis in cell walls.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Mental retardation GTPase activating protein
- Mental retardation GTPase activating protein
- Transmembrane Fragile-X-F-associated protein
- At1g25682
- Pectinesterase 31
Sequence:
MSSLRLRLCLLLLLPITISCVTVTLTDLPAFREAPAFRNGRECSKTTWIPSDHEHNPSIIHIAMTLDAIYLRGSVAGVFSVLQHASCPENIVFHFIATHRRSADLRRIISSTFPYLTYHIYHFDPNLVRSKISSSIRRALDQPLNYARIYLADLLPIAVRRVIYFDSDLVVVDDVAKLWRIDLRRHVVGAPEYCHANFTNYFTSRFWSSQGYKSALKDRKPCYFNTGVMVIDLGKWRERRVTVKLETWMRIQKRHRIYELGSLPPFLLVFAGDVEPVEHRWNQHGLGGDNLEGLCRNLHPGPVSLLHWSGKGKPWLRLDSRRPCPLDSLWAPYDLFRYSPLISDS
Protein: Tetrahydrocannabinolic acid synthase (THCA synthase) (EC 1.21.3.7) (Delta(1)-tetrahydrocannabinolic acid synthase) (Q8GTB6)
Organism: Cannabis sativa (Hemp) (Marijuana)
Function: Oxidoreductase involved in the biosynthesis of cannabinoids-related terpenophenolic natural products, which have pharmacological activity. Catalyzes the oxidative cyclization of the monoterpene moiety in cannabigerolic acid (CBGA), producing delta(9)-tetrahydrocannabinolate (THCA), the major cannabioid in drug-type Cannabis plants. Can also use cannabinerolic acid as substrate, but not cannabigerol or cannabinerol.
Subcellular location: Secreted {ECO:0000269|PubMed:16024552}. Secreted, extracellular space, apoplast {ECO:0000269|PubMed:16024552}. Note=Sorted from the secretory cells into the storage cavity of glandular trichomes. {ECO:0000269|PubMed:16024552}.
Interaction partners:
Sequence:
MNCSAFSFWFVCKIIFFFLSFHIQISIANPRENFLKCFSKHIPNNVANPKLVYTQHDQLYMSILNSTIQNLRFISDTTPKPLVIVTPSNNSHIQATILCSKKVGLQIRTRSGGHDAEGMSYISQVPFVVVDLRNMHSIKIDVHSQTAWVEAGATLGEVYYWINEKNENLSFPGGYCPTVGVGGHFSGGGYGALMRNYGLAADNIIDAHLVNVDGKVLDRKSMGEDLFWAIRGGGGENFGIIAAWKIKLVAVPSKSTIFSVKKNMEIHGLVKLFNKWQNIAYKYDKDLVLMTHFITKNITDNHGKNKTTVHGYFSSIFHGGVDSLVDLMNKSFPELGIKKTDCKEFSWIDTTIFYSGVVNFNTANFKKEILLDRSAGKKTAFSIKLDYVKKPIPETAMVKILEKLYEEDVGAGMYVLYPYGGIMEEISESAIPFPHRAGIMYELWYTASWEKQEDNEKHINWVRSVYNFTTPYVSQNPRLAYLNYRDLDLGKTNHASPNNYTQARIWGEKYFGKNFNRLVKVKTKVDPNNFFRNEQSIPPLPPHHH
Protein: Aquaporin-B (Q54WT8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Putatively gated water-specific channel, requiring a cysteine residue within the channel. Impermeable to water, glycerol and urea when expressed in Xenopus oocytes. Not regulated by pH; channels remain impermeable to water at pH 7.4 and 5.2.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22262860}; Multi-pass membrane protein {ECO:0000269|PubMed:22262860}. Cytoplasmic vesicle {ECO:0000269|PubMed:22262860}. Note=Expressed in lamellipodia-like protrusions of the plasma membrane and intracellular vacuolar structures. {ECO:0000255, ECO:0000269|PubMed:22262860}.
Interaction partners:
- Acyl carrier protein, mitochondrial
Sequence:
MSLKRSDDYQDLEEGIAMEDGGNIKDEEEKPLDPIEEQNKKRWVLIRAVLGELLCTFLFVYVLCATSANFIRLGSPPNPVVGGLSTGFAAVALIYSFADVSGAHFNPAVTFATCVTRKTSITKGLMYVGAQLVGSVLASLILLATFPGNFPGDKNAASAVAIAPSTDANIGNAFLTELVLTFILVYVIFAVAFDTVDNSVKTKVVGKSSSNNLTIYTTSGQTKAGFAPIAIGFTLGFLCFLGGSVSGGAFNPARVFGTALVGNNWTRHWMYWIADFLGAGLAGFAQKFFSSTHK
Protein: Tropomodulin, isoform M (A0A0B4K7R6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSDIEDVFGGSAEETKPEPDAQSKTSVVTEHTEEVIPGETEKMVTETIDEDGDVVEETTEVTRKTVKRTMKITETSATTKTTTLTTPAKLYGKDLSEYDDVDVESLLAQLSPEEITILAKEVDPDDNFLPPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEEIIDLAAILGFHSMMNQDQYHASLLNKGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRIGRQRRMGHLTRNYTVGVWQ
Protein: Uncharacterized protein C15D4.11c (O74316)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion.
Interaction partners:
Sequence:
MLRKAISTARNFKYPLFNCERRFSYFDMFRSKRKFTSGILTEQLALKLDSELGYVKQVLDETLPKKGYEKALHSFIIHEDPSLNYISALKETAKERIRVTVPVYSSRKSYVQTKPITHSAENENGNETSDELVFFQHSIPAYVQLTNNHGTILCALILCKGMLHFDSISFQSPQNSQAFSSDLRLILQKSQKYTGRKTKHVPASIKSSLLEFLDEQGITVKFMKALISRSWRKENVSYKHWIHNIIGFILPSESSTTKKSDSQ
Protein: BTB and CNC homology 1, basic leucine zipper transcription factor 1 (Transcription regulator protein BACH1b isoform 2) (Q502I2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSVESSKSFKFTFQSSVHSSHVLQCLNEQRKKDLLCDVTVVAGSQSFRAHRAVLASCSDYFSARVSTHTPESIVINLPDEITSEGFEPLLEFAYTSKLLFTKENVLEIRNCASVLGFRNLDKACFDFLLPKFFDSNRGTFFAQNINIRVRHGGSVVCTVASQ
Protein: Mitochondrial Rho GTPase (EC 3.6.5.-) (A0A8I6AMM4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004200, ECO:0000256|PIRNR:PIRNR037488}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004200, ECO:0000256|PIRNR:PIRNR037488}.
Interaction partners:
Sequence:
MIFLLTARVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNESGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIVCDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSVSPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR
Protein: Protein clpf-1 (P52874)
Organism: Caenorhabditis elegans
Function: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03035}.
Interaction partners:
- Polyadenylation and cleavage factor homolog 11
- Conserved regulator of innate immunity protein 3
- Suppressor of forked domain-containing protein
- Pre-mRNA polyadenylation factor Fip1 domain-containing protein
- TPR_REGION domain-containing protein
- Uncharacterized protein ZK1128.3
- 3'
- Cleavage and polyadenylation specificity factor subunit 4
- Cleavage and polyadenylation specificity factor subunit 3
- Probable cleavage and polyadenylation specificity factor subunit 1
Sequence:
MSEENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAAGNSNKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGAEQLPDSCLPFGMEVENHETKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLDDQIKR
Protein: Pumilio homolog 6, chloroplastic (APUM-6) (AtPUM6) (Q9C5E7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2.
Subcellular location: Plastid, chloroplast {ECO:0000305}. Cytoplasm {ECO:0000305}.
Interaction partners:
- Putative pumilio homolog 22
- Pumilio homolog 26
- Pumilio homolog 23
- DEAD-box ATP-dependent RNA helicase 40
- Protein EXPORTIN 1B
- Cytochrome P450 71B34
- Probable boron transporter 3
- Protein EXPORTIN 1A
- Polyadenylate-binding protein RBP47B'
Sequence:
MATENPIRISGSNERWSNSRKVSVPNRSGSAPPNMEGSFLAVDNLLSRQGGSVYNNLMLPRYGFEEPVTTHPSSKHSLNRIPSPPIYYPTEYQFIDNRVGRFRSNQGLNKVNSPIHLSQGKLSTHKEVSEDESSQQLSVNSVSDRTDGLDIRLSPGSQSLADFRQDDTSSGQTPQHSRSNSSNGEVNTADESGNFSELSDDVVVKDNAASTARASIGNEKSPDESTIISKMKSTNISGPGTAKYPREPRYGQPERQPHQQQNNATWIQGGSNMGSHGVNDAVIGAGQFHYGQPYKFSGDGQPVLQSSGFTPPLLYTATQTAYMTSPAHVYNMQSPAVYSPQYGYGPYTNMIPQFMPGYPSHGSVPVVVSPDFIPQLSGPSAGSVVHGGEMQYAEKLYVPPGQPSFPDPMYMQYCQQSFGQMEPLAPRNHTNAPESQKDDPKFLRQIRGPSNSNMARPGMGVNYYGIQPNMGIMVQYLPTHLGPPLSPGHVPYVEAYPGWQPQGSLEGANGPRLCNFLEELKSGKGRRFDLSDITGHIVEFSADQHGSRFIQQKLENCKPEEKAAVFREILPHACKLMTDVFGNYVIQKFFEYGNSTQRKELADQLMGQIVPLSLQMYGCRVIQKALDVIEPDQRVRLARELDGQVMRCVRDQNGNHVIQKCIENIPADKVGFMLYAFRGQVSSLSMHPYGCRVIQRLLERCSHDHQCRFITEEILESVCVLSKDQYGNYVTQHVLEKGTSEERERIGRKLSGHIVQLSLHKFASNVIEKCLEYGGRVERDLIIKEIAGPDESYNSLLMMMKDQYGNYVVQKIFETCTADQRLTLFSRVRMHASALKKYTYGKHIVSRLEQPSIEENQELRR
Protein: Jim, isoform I (M9PIL6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNPGAIGATPAQWGSEMYPNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQPQSPPGGGQEARDNGSGDGRQQQVSPSSSPYPSVQQQQRANGAGDEDPMNHQLANQQNPAPNQNQSSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQGGMLAPPGFPPLHYLNKGVLPMEQSGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGAGANGSGGVGGATGASVGVGSVGVTSGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNTTKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQVANHLMNDAKSLAAQQFLNNNNPSAVDNKANILPVRSIASNAAAAAVVQQSVVKNELYFPQCYGPPFQHPFQAQQQQAQQPSVAHANGGPTPPVTVTVANSVASGVVVQQNASASVVAQ
Protein: PAR domain protein 1 (Q9TVY0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
NTASAVAQQQQAHENSLVNSLVGVINNSDNNNNNTNNNNNNNTNSNSNNNNNNSVGGDDNNRWTQFQVQQLWKQHANYLNGKSTSNSKEIICPDDKYKEEGDIWNVEAQTAFLGPNLWDKTLPYDADLKVTQYADLDEFLSENNIPDGLPGTHLGHSSGLGHRSDSLGHAAGLSLGLGHITTKRERSPSPSDCISPDTLNPPSPAESTFSFASSGRDFDPRTRAFSDEELKPQPMIKKSRKQFVPDELKDDKYWARRRKNNIAAKRSRDARRQKENQIAMRARYLEKENATLHQEVEQLKQENMDLRARLSKFQDV
Protein: Golgi to ER traffic protein 2 (Guided entry of tail-anchored proteins 2) (Hydroxyurea resistance protein 2) (Required for meiotic nuclear division protein 7) (P40056)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in DNA replication and DNA damage response and also in cell wall function.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Interaction partners:
- ATPase GET3
- Golgi to ER traffic protein 1
- Golgi to ER traffic protein 4
- Small glutamine-rich tetratricopeptide repeat-containing protein 2
- Ubiquitin-like protein MDY2
- SRP-independent targeting protein 2
Sequence:
MSELTEAEKRRLLRERRQKKFSNGGASSRLNKITGQASSHLNAESPLDAPSAAKTTPPASVHSATPDIKEDSNVAPQLDLLKQLAAMQGQGTGKSTPQDSSTPDLLSLLSSMNTGMPSAEGTPSFGQAAPAAPINQAALDYHDYLLNRLKAWTILVKWVFFLLPYLYLITRPNSSVWPAYAFTQSAWFAPLRNPSNFTRIFATFEFLSISIYYQLLKNVEHKSKIKNLQDTNKLVKLVSLVPEGVIPVANLKGKLITLLQYWDLLSMLITDISFVLIVLGLLTYL
Protein: DNA-directed RNA polymerase subunit (EC 2.7.7.6) (A0A8I6ASE2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDVTRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPEDSDEEN
Protein: cAMP-regulated phosphoprotein 19 (ARPP-19) (Q712U5)
Organism: Rattus norvegicus (Rat)
Function: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12944371, ECO:0000269|PubMed:2158525}.
Interaction partners:
- Serine/threonine-protein kinase greatwall
- Misshapen-like kinase 1
Sequence:
MSAEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAPDKTEVTGDHIPTPQDLPQRKPSLVASKLAG
Protein: Cell number regulator 1 (ZmCNR01) (B6TZ45)
Organism: Zea mays (Maize)
Function: Acts as a negative regulator of cell number.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Zinc finger CCCH domain-containing protein 4
- AGAMOUS-like protein
- BHLH transcription factor
- Transcription factor bHLH51
- BHLH transcription factor
- BHLH transcription factor
- DNA binding protein
Sequence:
MYPSAPPDAYNKFSAGAPPTAPPPPAAYHQQQQQHGANMDTSRPGGGLRKWSTGLFHCMDDPGNCLITCLCPCVTFGQVADIVDKGTCPCIASGLVYGLICASTGMGCLYSCLYRSKLRAEYDLDEGECPDILVHCCCEHLALCQEYRELKNRGFDLGIGWEANMDRQRRGVAGGGAVMGAPPAIPLGMIR
Protein: Protein DPCD (Q8BPA8)
Organism: Mus musculus (Mouse)
Function: May play a role in the formation or function of ciliated cells.
Interaction partners:
- RuvB-like 1
- RuvB-like 2
- Dynein axonemal assembly factor 10
Sequence:
MAVTSWLEVLRSAEKTALLQDGKRMVHYLFPDGKEMAEEYDEKTSELLVRKWRVKNALGALGQWQLEVGEPVPSGAGSLGSELIKESNANPIFMRKDTKTSFQWRIRNLPYPKDVYSVSVAQKERCVIVRTTNKKYYKKFSIPDLDRHQLPLEDSALSFAHANCTLIISYQKPKEVMAAESELQKELKKVKTAHGSAGDCKTQ