wanglab/gogpt-training-data huggingface dataset:
Protein: Ceramide synthase 1 (CerS1) (Longevity assurance gene 1 protein homolog 1) (Protein UOG-1) (Sphingoid base N-stearoyltransferase CERS1) (EC 2.3.1.299) (P27545)
Organism: Mus musculus (Mouse)
Function: Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward stearoyl-CoA (octadecanoyl-CoA; C18:0-CoA). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a predominant role in skeletal muscle in regulating C18 ceramide and dihydroceramide levels with an impact on whole-body glucose metabolism and insulin sensitivity. Protects from diet-induced obesity by suppressing the uptake of glucose in multiple organs in a FGF21-dependent way. Generates C18 ceramides in the brain, playing a critical role in cerebellar development and Purkinje cell function. In response to cellular stress mediates mitophagy, a known defense mechanism against cell transformation and aging. Upon mitochondria fission, generates C18 ceramides that anchor lipidated MAP1LC3B/LC3B-II autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P27544}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAAAAATPRLEAPEPMPSYAQMLQRSWASALAAAQGCGDCGWGLARRGLAEHAHLAAPELLLAVLCALGWTALRWAATTHIFRPLAKRCRLQPRDAARLPESAWKLLFYLACWSYCAYLLLGTSYPFFHDPPSVFYDWRSGMAVPWDIAVAYLLQGSFYCHSIYATVYMDSWRKDSVVMLVHHVVTLLLIASSYAFRYHNVGLLVFFLHDVSDVQLEFTKLNIYFKARGGAYHRLHGLVANLGCLSFCFCWFWFRLYWFPLKVLYATCHCSLQSVPDIPYYFFFNILLLLLMVMNIYWFLYIVAFAAKVLTGQMRELEDLREYDTLEAQTAKPCKAEKPLRNGLVKDKLF
Protein: Membrane associated histidine-rich protein 1 (C0H5L9)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Skeleton-binding protein 1
- Ring-exported protein 1
Sequence:
MAEQAAVQPESVPTVGTVPQADVPTEGMDVPFGFFDKNTLKKLMFIFMRDVDNYARNWFTNFMHAQTEDDDQTDGEGKHAYLLNHKRTWFEQFKASLSEALDGKNSVFLLLFLFFGFVFCLLYHAFLYHSIKSEHKAKKLHLEQEENDDDYHHYHHAPHFYPFFDPEYMHDHDHDHEHDHTIKPAHAHELDHGHDHGHDHGHDHGHDHGHDHGHGHGGHVCTCKNKAKKKPGEPCDCQKAKLEQEKKDN
Protein: Sodium/hydrogen exchanger 9B1 (Na(+)/H(+) exchanger-like domain-containing protein 1) (NHE domain-containing protein 1) (Sodium/hydrogen exchanger-like domain-containing protein 1) (Solute carrier family 9 subfamily B member 1) (Testis specific sodium-hydrogen exchanger) (MtsNHE) (Q8C0X2)
Organism: Mus musculus (Mouse)
Function: Sperm-specific Na(+)/H(+) exchanger involved in intracellular pH regulation of spermatozoa. Involved in sperm motility and fertility.
Subcellular location: Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:19409551, ECO:0000269|PubMed:20036903, ECO:0000269|PubMed:27010853}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Solute carrier family 9 member C1
Sequence:
MSEHDVESNKKDDGFQSSVTVEMSKDPDSFHEETVEPKPELKEPEPKEPEPKEPERKEPERKEPERKEPERKEPERKVPGRRETQTKETQTTEIERKETKKKRGTNSYCPPQGTINKTITDGAALIALWTLLWALIGQEVLPGGNLFGLVVIFYSAFLGGKILEFIKIPVVPPLPPLIGMLLAGFTIRNVPIIYEFVHIPTTWSSALRNTALTIILVRAGLGLDPQALKHLKGVCLRLSFGPCFLEACSAALFSHFIMNFPWQWGFLLGFVLGAVSPAVVVPNMLMLQENGYGVEKGIPTLLVAASSMDDIVAITGFNTFLSIVFSSGSVISNILSSLRDVLIGVLVGIVMGVFVQYFPSGDQERLTQRRAFLVLSMCISAVLGCQHIGLHGSGGLVTLVLSFMAAKRWAEEKVGIQKIVANTWNVFQPLLFGLVGTEVSVESLESKTIGMCLATLGLALSVRILSTFVLMSFANFRFKEKVFIALSWIPKATVQAVLGPLALETARVMAPHLEGYAKAVMTVAFLAILITAPNGALLIGILGPKILEQSEVTFPLKVELSNFHH
Protein: Lipopolysaccharide export system protein LptA (P0ADV1)
Organism: Escherichia coli (strain K12)
Function: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
Subcellular location: Periplasm {ECO:0000255|HAMAP-Rule:MF_01914, ECO:0000269|PubMed:17056748, ECO:0000269|PubMed:18480051, ECO:0000269|PubMed:20446753}. Note=Associates with both the inner membrane and the outer membrane.
Interaction partners:
- Lipopolysaccharide export system ATP-binding protein LptB
- Lipopolysaccharide export system permease protein LptG
- Lipopolysaccharide export system protein LptC
- LPS-assembly protein LptD
- LPS-assembly lipoprotein LptE
- Lipopolysaccharide export system permease protein LptF
- 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
- Outer membrane protein assembly factor BamA
- Phosphoethanolamine transferase EptA
- Phosphoethanolamine transferase EptC
Sequence:
MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQSLDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNGKPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRVTTVLVPSQLQDKNNKGQTPAQKKGN
Protein: tRNA (32-2'-O)-methyltransferase regulator THADA (Gene inducing thyroid adenomas protein) (Thyroid adenoma-associated protein) (Q6YHU6)
Organism: Homo sapiens (Human)
Interaction partners:
- tRNA
Sequence:
MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQLTDGVSQIHYIKQIVPLLEKADKNGMCDPTIQSCLDILAGIYLSLSLKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLKNVLHFLQKSLIEILEENRKCAGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEKIPHLISSVLLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRILASWTNSAIQVLESSSPSLTDSLNGNSSIVGRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWHIKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRNHKSHLKSQTAESSWIDQWHETWVSPLLFILCEGNLDQKSYVIDYYLPKLLSYSPESLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDARIKQGLIHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILAFDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQMILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLKITMKELISLAGPTDDIQSTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMRCGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDITVCTKAKLWLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGIISGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAKSGERETNVPISFSQLLESAFPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKILHCMDPGEWLPQTEHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLFLTNPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILLGWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPAAEFVKTVEFTRLRIQEERTLACLRLLAFLEGKEGEDTLVLSVWDSYAESRQLTLPRTEAAC
Protein: Small-conductance mechanosensitive channel (P0C0S1)
Organism: Escherichia coli (strain K12)
Function: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activity that last for a few seconds.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:10202137, ECO:0000269|PubMed:12551944, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:23012406, ECO:0000269|PubMed:23074248, ECO:0000269|PubMed:2436228, ECO:0000269|PubMed:7595939}; Multi-pass membrane protein {ECO:0000269|PubMed:12446901, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:23012406, ECO:0000269|PubMed:23339071, ECO:0000269|PubMed:26551077}.
Interaction partners:
- Large-conductance mechanosensitive channel
- Mechanosensing system component YbdG
- Moderate conductance mechanosensitive channel YbiO
- Proline/betaine transporter
Sequence:
MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLIIARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGAAGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADGKIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKDREMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVNFKRVKEDKAA
Protein: Uncharacterized oxidoreductase Rv1144 (EC 1.-.-.-) (P9WGQ7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Alpha-methylacyl-CoA racemase
- Probable fatty acid synthase Fas
- Probable enoyl-CoA hydratase EchA10
Sequence:
MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDRARFAQADVTDEAAVSNALELADSLGPVRVVVNCAGTGNAIRVLSRDGVFPLAAFRKIVDINLVGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIARDLASKLIRVVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIRLDGAIRMAPR
Protein: Voltage-gated potassium channel regulatory subunit KCNG2 (Cardiac potassium channel subunit) (Potassium voltage-gated channel subfamily G member 2) (Voltage-gated potassium channel subunit Kv6.2) (Q9UJ96)
Organism: Homo sapiens (Human)
Function: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q14721}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P63142}.
Interaction partners:
- Ubiquitin-like protein FUBI
- Protein cornichon homolog 3
Sequence:
MEPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
Protein: Caveolin (W5UMJ4)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202, ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202, ECO:0000256|RuleBase:RU000680}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein {ECO:0000256|RuleBase:RU000680}. Membrane, caveola {ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein {ECO:0000256|RuleBase:RU000680}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
Interaction partners:
- Caveolin
- Tyrosine-protein kinase
- Tyrosine-protein kinase
- Tyrosine-protein kinase
- Tyrosine-protein kinase
- Caveolae-associated protein 1b
- Caveolae-associated protein 1
- Integrin beta
- Integrin beta
- Integrin beta
Sequence:
MTGGPKDGETEEYVHSPFIRKQGNIYKPNNKDMDSDSIHEKTLHDVHTKEIDLVNRDPKHLNDHVVKVDFEDVIAEPPGTYSFDGVWKASFTTFTVSKYWFYRLLTALVGIPLALIWGLFFAILSFLHIWAVVPCVKSYLIEIHCVSQVYSICVHTFCDPLFEAMGKCFSNVRVTSTKVV
Protein: Major fimbrium tip subunit FimD (B2RH58)
Organism: Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Function: Probably a component of the fimbrium tip. These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome. They play an important role in invasion of periodontal tissues and are major virulence factors. FimC, FimD and FimE contribute to interaction with host CXCR4 and thereby down-regulate the TLR2-mediated host immune response.
Subcellular location: Fimbrium {ECO:0000269|PubMed:17526848}. Cell outer membrane {ECO:0000305}. Note=Probably synthesized as a palmitoylated precursor. Efficient export to the outer membrane and integration into fimbriae requires lipidation and subsequent proteolytic removal of the lipidated propeptide (Probable). Probably part of the fimbrium tip, as a part of the complex formed by FimC, FimD and FimE. {ECO:0000305, ECO:0000305|PubMed:17675496}.
Interaction partners:
Sequence:
MRTNRILNIICPPILFLLVGFLFGCVREDIESDMNETSSLFLQVQPYNQRSEEGGVAAYDENTIERLTLVFYKNGTKVWQAEPVETSPSSNSYYVPVPESMYGQFNGNNSFKIYLVANVNFSGSFEPNASETSFLKTLVPNSILLQNDGKPEDKFAMIGSVEKQINMATSEGKQLGSIELKRVAAKLRLKKPVLNISDYELVGDPKAKFRNCMPKGFLSVEEKPEGVGYEAIDYRPMTEANSSVHFYSYYNEWALNNEGRPEFVMMLKLKKTGTDDNTAKPYYYRIPVDGSDKKIRSNHLYDMAVTIEVLGSLNEEDPVTINGSLSVIEWTSHSDDQTLPDVQYLEVIPQETVMNMTTEIELDYFSSHSLLPPADVKATCTYVNSNGQQITDTYTGANVPTVTIDANTKKIKVRSILPINNIPKDISFTIKNSIGFEKKIKIRQNPSQFIINTFGTKSSWQPEGNLAPNLNNKAIYQIVVLSPPADGNMIIGFPPTKEVGFYKKSGSSYTLKHTDRITEQDEQTANMVSPSFELASQLGATLVQDHWEYYTLNPLRLIYHSNQQNRYALMTCAFYWEERKKADGTIERLDDWRLPTRAEIQLVDKLQREQAGVVRDIMTGRYYWSGLPDKAIKILLPTASGNATEQRAHVRCVRDVKNDRFVKSAKRLKK
Protein: Probable 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (L-AIBAT) (Q21217)
Organism: Caenorhabditis elegans
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- Succinate-semialdehyde dehydrogenase, mitochondrial
- Glutamate decarboxylase 1
- Aldehyde dehydrogenase domain-containing protein
- Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial
- Putative aldehyde dehydrogenase family 7 member A1 homolog
- Aldehyde dehydrogenase domain-containing protein
- Alanine--glyoxylate aminotransferase 2, mitochondrial
- Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial
- Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1
- Aldehyde dehydrogenase
Sequence:
MLPRLAKSSLIQQVRGVSAIANAEPSGPSISTSIPGPKSKALKQEMDKVHQTTSVRFHVDYEKSFGNYVVDADGNALLDVYTQISSLPLGYNHPDLVKVASQPHLITSLVSRPALGSFPRTDFADGISHALTSIAPKGLKAVQTMLCGTSANENAIKTAFIWYQAQRRGGLGPDALHLESCMNQQKPGTPNLSVMGFEGAFHGRSLCMLSVTRSKPIHKVDIPAFDWPIAKFPRYKYPLDQNVAYNKKQDQECLADVEAKISEWKRRDNDVAAIIVEPIQAEGGDHYGSPAFFQGLRDITSKHGIVFIVDEVQTGGGATGDIWAHDHWNLSSPPDMVTFSKKLLTGGYFYGEHLRVKEAYRIYNTWMGDPTKLLLLEKAVEVIKRDGLIEQSREVGAEFQKRLGELQASSGGKLDQARGRGTFAAVDFPSGSLRDKFVDLAISNGLHCGGCGDRSLRFRPSLVYTKKHLDLTFDLLDKTLKGL
Protein: Agamous-like MADS-box protein AGL15 (Q38847)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Acts as both an activator and a repressor of transcription. Binds DNA in a sequence-specific manner in large CArG motif 5'-CC (A/T)8 GG-3'. Participates probably in the regulation of programs active during the early stages of embryo development. Prevents premature perianth senescence and abscission, fruits development and seed desiccation. Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4. Can enhance somatic embryo development in vitro.
Subcellular location: Nucleus. Cytoplasm. Note=Associated with the chromosomes during mitosis. Accumulates in the egg cytoplasm before fertilization but moves into the nucleus of the fertilized egg.
Interaction partners:
- Histone deacetylase complex subunit SAP18
- B3 domain-containing transcription factor LEC2
- B3 domain-containing transcription factor FUS3
- Nuclear transcription factor Y subunit B-9
- Somatic embryogenesis receptor kinase 1
- Protein WUSCHEL
- Histone deacetylase 19
- B3 domain-containing transcription factor ABI3
- Floral homeotic protein APETALA 2
- Nuclear transcription factor Y subunit B-6
Sequence:
MGRGKIEIKRIENANSRQVTFSKRRSGLLKKARELSVLCDAEVAVIVFSKSGKLFEYSSTGMKQTLSRYGNHQSSSASKAEEDCAEVDILKDQLSKLQEKHLQLQGKGLNPLTFKELQSLEQQLYHALITVRERKERLLTNQLEESRLKEQRAELENETLRRQVQELRSFLPSFTHYVPSYIKCFAIDPKNALINHDSKCSLQNTDSDTTLQLGLPGEAHDRRTNEGERESPSSDSVTTNTSSETAERGDQSSLANSPPEAKRQRFSV
Protein: Glucosylceramidase (EC 3.2.1.45) (B7Z6E6)
Organism: Homo sapiens (Human)
Subcellular location: Lysosome membrane {ECO:0000256|ARBA:ARBA00004207}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004207}; Lumenal side {ECO:0000256|ARBA:ARBA00004207}.
Interaction partners:
Sequence:
MEFSSPSREECPKPLSRVSVMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRPSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ
Protein: protein-serine/threonine phosphatase (EC 3.1.3.16) (F4K124)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAMIGMNIIGLFMVLMLLLISLIILFACKPWRYFSRFRSSSRFSSTFKVGDLQRPLISDDGNLIQGQTSEVTREYDLEGACYQNDGLLHSSLTEGRFYKQRLPSSSPHFSQGESFVLEVISEPSDNALVGQTLKLPAEKGSLAEVQTYDWQNNRNENLQYNLEKDRLINLSPRLVEDQRSWLFLEVIAGPAIGLQHAVNSTSSSKLPVKLGRVSPSDLALKDSEVSGKHAQITWNSTKFKWELVDMGSLNGTLVNSHSISHPDLGSRKWGNPVELASDDIITLGTTTKVYVRISSQNEFQIPFKIGVASDPMAMRRGGRKLPMEDVCHYKWPLPGANKFGLFCVCDGHGGSGAAQSAIKIIPEVLANILSDSLRKEKVLSKRDASDVLRDMFAKTEARLEEHQYEGCTATVLLVWKDNEENFFAQCANLGDSACVIQNKDLACLKRDLGGRYIQMTEDHRVVSLSERKRFQEAGLALRDGETRLFGINLARMLGDKFPKQQDSRFSAEPYISEPLRIDQSSKDVFAVLASDGLWDVVSPKKAVQLVLQMRDKERGRESSAEKIANGLLNEARAMRTKDNTSIIYLDFDTSL
Protein: Protocadherin 11 X-linked (F6ZNL5)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MDLLSGTYIFAVLLACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESVPNATLIYELVRRSIDAPANQNTETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQPPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVTIEEAKPDDGENERNSVTLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKAPVSVHIRPTMKEVVRSHTPMKEATTVEIWTHPHPQRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHDAGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDTCTQECLILGHSDSCWMPATLTNPSPSQIKTSAICHSPPRPRLSVRRYSPPVTQTVTICHSPPVTQAIALCHSPPPVQVTVPRHSPPPAQASAVSYSPTLVQAVVIHHSPPLPQAATHHRTQAQPPMGLQQGWVQGAGADGLYPIDQGVQGSTRAQFYTMAERFHPDDDSIKVIPLTTFTSGQQARSSRGDSPIIEEHPL
Protein: Peptidase S54 rhomboid domain-containing protein (A0A0H2US45)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFGAMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYLLSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVVNIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILLFYKGMGL
Protein: RING finger protein ETP1 homolog (BRAP2 homolog) (O13747)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MYYYLEIECESPVKDIFTCNKRRASKVVGNSFGGDHFNFRLGEIKLLSMDFPSSKVPEVEETSLGHGVVHLYRVFPSESHEFDAPGLILAILAIPLYMSPSDVLGFLGEKHCKSIQHIRLLKTKDPNRIMALLKFKDQASVIRFYTEFNGKAFSQIDPETCHVLHIDKVNIKYPMESSDSSSTEQQLVGPSSKPFASTTPALIELPTCVVCLERMDSSITGLITIVCQHTFHCPCLQKWGNSSCPVCRYTQKVQSSEFQSKCTVCCYDKDLWICLICGNIGCGRYHDAHAKQHYVDTAHCYAMELETQRVWDYAGDNYVHRLLQSETDGKLVELSTDGKSSGWTGSSATESKLRDKMGLEYTQILVSQLESQRLYYESHLSNMSQKLSRVNEELVLKTKIATASSNANTDLRSRVDISESKLKKRDDKLKRVSSQLEHLKHNYEEEKSMNENLLVRIQTLEKQNTTKSDQIVSMQFQINDLNEQLRDLMFTISASQEIQKMGQSEELQNGTIVLPNNSTVRSNSVKSKKKKKKKPVVPSSSGSLGTD
Protein: Putative adhesion G protein-coupled receptor E4P (EGF-like module receptor 4) (EGF-like module-containing mucin-like hormone receptor-like 4) (G-protein coupled receptor 127) (G-protein coupled receptor PGR16) (Q86SQ3)
Organism: Homo sapiens (Human)
Function: May mediate the cellular interaction between myeloid cells and B-cells.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000250|UniProtKB:Q91ZE5}; Multi-pass membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MGSRFLLVLLSGASCPPCPKYASCHNSTHCTCEDGFRARSGRTYFHDSSEKCEDINECETGLAKCKYKAYCRNKVGGYICSCLVKYTLFNFLAGIIDYDHPDCYENNSQGTTQSNVDIWVSGVKPGFGKQLPGDKRTKHICVYWEGSEGGWSTEGCSHVHSNGSYTKCKCFHLSSFAVLVALAPKEDPVLTVITQVGLTISLLCLFLAILTFLLCRPIQNTSTSLHLELSLCLFLAHLLFLTGINRTEPEVLCSIIAGLLHFLYLACFTWMLLEGLHLFLTVRNLKVANYTSTGRFKKRFMYPVGYGIPAVIIAVSAIVGPQNYGTFTCWLKLDKGFIWSFMGPVAVIILINLVFYFQVLWILRSKLSSLNKEVSTIQDTRVMTFKAISQLFILGCSWGLGFFMVEEVGKTIGSIIAYSFTIINTLQGVLLFVVHCLLNRQVRLIILSVISLVPKSN
Protein: Probable indole-3-acetic acid-amido synthetase GH3.1 (EC 6.3.2.-) (Auxin-responsive GH3-like protein 1) (AtGH3-1) (O82333)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin.
Interaction partners:
- Auxin transporter protein 1
- Auxin-responsive protein IAA26
- Auxin-responsive protein IAA1
- Auxin-responsive protein SAUR32
- Auxin-responsive protein IAA4
- Protein TRANSPORT INHIBITOR RESPONSE 1
- Auxin transporter-like protein 2
- Serine/threonine-protein kinase SRK2F
- Auxin-responsive protein IAA9
Sequence:
MAVDSNLSSPLGPPACEKDAKALRFIEEMTRNADTVQENLLAEILARNADTEYLRRFNLCGATDRDTFKTKIPVITYEDLQPEIQRIADGDRSPILSAHPISEFLTSSGTSAGERKLMPTIKEELDRRQLLYSLLMPVMNLYVPGLDKGKGMYFLFVKSETKTPGGLPARPVLTSYYKSEHFRSRPYDPYNVYTSPNEAILCPDSFQSMYTQMLCGLLDRLSVLRVGAVFASGLLRAIRFLQLHWSRFAHDIELGCLDSEITDPSIRQCMSGILKPDPVLAEFIRRECKSDNWEKIITRIWPNTKYLDVIVTGAMAQYIPTLEYYSGGLPMACTMYASSECYFGLNLNPMSKPSEVSYTIMPNMAYFEFIPLGGTKAVELVDVNIGKEYELVVTTYAGLCRYRVGDILRVTGFHNSAPQFHFVRRKNVLLSIDSDKTDESELQKAVENASSILHEECGSRVAEYTSYADTSTIPGHYVLYWELLVRDGARQPSHETLTRCCLGMEESLNSVYRQSRVADNSVGPLEIRVVRNGTFEELMDYAISRGASINQYKVPRCVNFTPIVELLDSRVVSAHFSPSLPHWTPERRRR
Protein: Olfactory receptor 8S1 (Q8NH09)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Beta-arrestin-1
Sequence:
MALGNHSTITEFLLLGLSADPNIRALLFVLFLGIYLLTIMENLMLLLMIRADSCLHKPMYFFLSHLSFVDLCFSSVIVPKMLENLLSQRKTISVEGCLAQVFFVFVTAGTEACLLSGMAYDRHAAICRPLLYGQIMGKQLYMHLVWGSWGLGFLDALINVLLAVNMVFCEAKIIHHYSYEMPSLLPLSCSDISRSLIALLCSTLLHGLGNFLLVFLSYTRIISTILSISSTSGRSKAFSTCSAHLTAVTLYYGSGLLRHLMPNSGSPIELIFSVQYTVVTPMLNSLIYSLKNKEVKGERSLRDSSHLPQLHKGQARWKRPAFTEGRREPGHPELSIPVTPQPQGACACSALRAAPTALP