wanglab/gogpt-training-data huggingface dataset:
Protein: Squalene synthase 10 (PgSS10) (SQS 10) (EC 2.5.1.21) (FPP:FPP farnesyltransferase SS10) (Farnesyl-diphosphate farnesyltransferase SS10) (A0A1P7Y0A2)
Organism: Panax ginseng (Korean ginseng)
Function: Component of the triterpene saponins (e.g. ginsenosides or panaxosides) and phytosterols biosynthetic pathways. Catalyzes the biosynthesis of squalene (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P53799}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGSLGAILKHPEDFYPLLKLKIAARHAEKQIPSEPHWAFCYSMLHKVSRSFGLVIQQLGPQLRDAVCIFYLVLRALDTVEDDTSISTEVKVPILMAFHRHIYDNDWHFSCGTKEYKVLMDEFHHVSNAFLDLGSGYKEAIEDITMRMGAGMAKFICKEVETIDDYDEYCHYVAGLVGLGLSKLFHASGAEDLATDSLSNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPRQIWSKYVDKLEDLKYEENSAKAVQCLNDMVTDALVHAEDCLKYMSDLRGPAIFRFCAIPQIMAIGTLALCFNNTQVFRGVVKMRRGLTAKVIDQTKTMSDVYGAFFDFSCLLKSKVDNNDPNATKTLSRLEAIQKICKNSGALTTKRKSYIIENESGYNSTLIVILFIILAILYAYLSSNLPNSL
Protein: Putative ATP-dependent DNA helicase fml2 (EC 3.6.4.12) (FANCM-like protein 2) (Q9HE09)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- ATP-dependent DNA helicase srs2
- Replication factor A protein 1
- Serine/threonine-protein kinase mph1
- DNA topoisomerase 3
- Swi5-dependent recombination DNA repair protein 1
- DNA repair protein rad8
- DNA repair protein rhp51
Sequence:
MIVLRDSSDYSDSEVDLPSIEVNGERGNVPTSVLCNVEGSLLNSNPALRQPNLKCIKHNQDVENTTFQLDLRGCRVPSSQPQVITELENNIDIPKNIDAMQNWIFPQTQQYRNYQKEFCEQALFHNLLLALPTGLGKTFIAAVVMLNYFRWFPESKIIFLAPTKPLLLQQRVACSNVAGMSPGATAELNGEVSPDRRLFEYNTKRVFFMTPQTLQNDLKEHLLDAKSIICLIFDEAHRATGNHSYAQVMRAVLRSNSHFRVLGLTATPGSSTASVQKVVDCLHISKLIVRNEESIDIRSYVFHKKIQLIKVTISSEMNILKSDFANLYRPYFNFLRQKKLIPINCECLNIKAYTLFVSLRKYSFSSKNVQSKEKSKIMSCFTLLISCAHITYLLDCHGIIQFYQKLVETKNKAEGKGSGQSFWLFTSKPFAFYLEHLHNKIQGLSLNHPKMNHLLELLKEHFKDTSEGYQNQRVMIFTEFRNTAEYITTTLLAIRPMVRASLFIGQANSAYSTGMNQMQQKETIDQFRAGVINTLVATSIGEEGLDIGDTDMIICYDASSSPIRTIQRMGRTGRKKSGKVFVLLTEDCEDSKWERSQVSYRRVQKVIESGKKIALKKDVPRLIPSNIQPIFKFQALQNNADATLILNSYNNNSSSLSPVNTLANQAHSRSKRYLPFIVDDVFEDMESNLRVPTEDAKIKRFKSDYRSCIYNARRNVFSKPTYMGDKLTKFAKVPHSLLTLSIYRRGRLLQQCSPSSVTKYLKYEEKFKRKRMKKTSNALFQST
Protein: Tumor necrosis factor ligand superfamily member 4 (OX40 ligand) (OX40L) (CD antigen CD252) (P43488)
Organism: Mus musculus (Mouse)
Function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 4
- Tumor necrosis factor receptor superfamily member 9
- CD27 antigen
- CD40 ligand
- Inducible T-cell costimulator
- Tumor necrosis factor receptor superfamily member 8
- Tumor necrosis factor receptor superfamily member 5
- Tumor necrosis factor ligand superfamily member 9
- T-cell-specific surface glycoprotein CD28
- CD70 antigen
Sequence:
MEGEGVQPLDENLENGSRPRFKWKKTLRLVVSGIKGAGMLLCFIYVCLQLSSSPAKDPPIQRLRGAVTRCEDGQLFISSYKNEYQTMEVQNNSVVIKCDGLYIIYLKGSFFQEVKIDLHFREDHNPISIPMLNDGRRIVFTVVASLAFKDKVYLTVNAPDTLCEHLQINDGELIVVQLTPGYCAPEGSYHSTVNQVPL
Protein: Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase JMJD7) (P0C870)
Organism: Homo sapiens (Human)
Function: Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Additionally, may play a role in protein biosynthesis by modifying the translation machinery. Acts as Fe(2+) and 2-oxoglutarate-dependent monooxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA).
Subcellular location: Nucleus {ECO:0000269|PubMed:29915238}. Cytoplasm {ECO:0000269|PubMed:29915238}.
Interaction partners:
Sequence:
MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLYLPALWFHHVQQSQGCIAVNFWYDMEYDLKYSYFQLLDSLTKASGLD
Protein: Achaete-scute homolog 1a (Zash-1a) (Pituitary-absent protein) (Q90259)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter (By similarity). Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Insulinoma-associated protein 1a
- Neurogenin-1
- Protein lin-28 homolog A
- Transcription factor HES-5
- Neurogenic locus notch homolog protein 1
- Paired box protein Pax-6
- Paired box protein Pax-6
- Neurogenic differentiation factor
- Heparin-binding EGF-like growth factor b.
- Transcription factor HES-5
Sequence:
MDITAKMEISVNQQQFMPPACFFASQSIQLSPTDSQCSNKSASKQAKRQRSSSPELLRCKRRLNFAGFGYSLPQQQPHAVARRNERERNRVKLVNNGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSPTISQNYSNDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
Protein: DNA-binding protein, putative (Q72E96)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
Sequence:
MVARIPYRREHSDQRRCPGPRPGFAARRKALSTFDEVFERIKLATNTRTQVELAEVLDIRQSSISDAKRRNSVPSDWYMKLFEKFGLNPDWLKKGSGPMYLRTDQGYEPLDAPVAGLVLEDPARYGDPDAKSSVATVFAMGCAVDENGVSQPLTAIAKLAVPQSFAAPGTQIVRVDAGAMEPVIGKGAFVGIDTTQKNIVSGELYGVFMPFEGVAIKRVFLDAANARFILRTENPTHPEQYLPIDQHADRIFGRIVWVLQRI
Protein: Thrombospondin-type laminin G domain and EAR repeat-containing protein (TSP-EAR) (J3S6Y1)
Organism: Mus musculus (Mouse)
Function: Plays a critical role in tooth and hair follicle morphogenesis through regulation of the Notch signaling pathway. May play a role in development or function of the auditory system.
Subcellular location: Secreted {ECO:0000269|PubMed:22678063}. Cell surface {ECO:0000269|PubMed:22678063}. Cell projection, stereocilium {ECO:0000269|PubMed:22678063}. Note=Secreted protein which may bind to the cell surface via a membrane receptor. {ECO:0000269|PubMed:22678063}.
Interaction partners:
- Cell adhesion molecule CEACAM16
- Protein shisa-8
- Endoribonuclease YbeY
- C2 domain-containing protein 2
Sequence:
MSALLMLCAVLLLLGTPSRGARPWEPCTDLRPLDILAEVVPLNGATSGIRMVQVEGVRGLQFSATEPRTTSFPASRIFSSCDFFPEEFSIIVTLRVPNLPPKKNEYLLSLLAEERDTLLLGLRYSPTQLHFLFLSEDLAGAWQTRVSFWSPGLMDSRWHTLILAVSQGSFSLTTDCGLPVDIMADVSFPPTLSVRGARFFIGSRKRTKGLFTGVIRQLVLLPGSDATPQLCPSRNARLAELSIPQVLKRLTGKPDDNEVLNYPYEADMKVTLGSRPPCTKAEGAQFWFDAAQKGLYLCAGSEWVSVLAAKTKLDYVEEHQSLHTNSETLGIEVFSIPGVGLFAAAANRKARSAIYKWTDGKFVSYQNIATHQAQSWRHFTIGKKIFLAVANFGPNERGQEFSVIYKWSPRKLKFTLYQRIATHSARDWEAFEVDGEHFLVVANHREGDNHNIDSMVYRWNPSSQLFEANQSIATSGAYDWEFFTVGPYSFLVVANTFNGTSTQVHSHLYIWLVGAFQLFQSFLTFGAADWEVFHIGERIFLAVANSHSYDVQMQAQNDSYVLSSVIYELNITAQTFVKFQDIPTCSALDWEFFSVGEDHFLVVANSFDGNTFSVNSIIYRWQGYEGFVAVHKLPTFGCRDWEAFNTTAGSYLIYSSAKEPLSRVLKLRTG
Protein: Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F) (Q4KMQ2)
Organism: Homo sapiens (Human)
Function: Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21107324, ECO:0000269|PubMed:22075693, ECO:0000269|PubMed:22946059}; Multi-pass membrane protein {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21107324, ECO:0000269|PubMed:22075693, ECO:0000269|PubMed:22946059}. Note=Shows an intracellular localization according to PubMed:22075693.
Interaction partners:
- Secretin receptor
- Protein kinase C-binding protein NELL2
- Protein kinase C-binding protein NELL1
- XK-related protein 8
Sequence:
MKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE
Protein: Probable 5-hydroxyisourate hydrolase R09H10.3 (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-like protein R09H10.3) (Q21882)
Organism: Caenorhabditis elegans
Function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Interaction partners:
- Probable 5-hydroxyisourate hydrolase ZK697.8
- Carrier protein
- LiPocalin-Related protein
Sequence:
MNKFSLFFALTATLMTITESAVPTASISAHVLDISGGSPAGGVQILAYIQQNDDWTKIGSEFTQDNGRVDWVSPDFTLIPGTYRLVYITEPYYKAKNVESFYPYVEVVFNIRDATQHYHVPLTLSPWGYSTYRGS
Protein: C2 domain-containing protein (Q38F79)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- B9 domain-containing protein 1
- B9 domain-containing protein 2
- Meckelin
- Transmembrane protein
- Meckel syndrome type 1 protein
Sequence:
MQKQTNAEPPLSPTTGSGFGTPLPLQDETPEDHAHVEGNDAAQHFLELLSPSSRGGNASALKKGKKNTNRRLRFDPTLRVVEAAEAPVQANTEDGSSSEEDSDSWRGKSLTATEEGGLSDVPEPELTELSNRQVTRRPPWWVHRWSELSLFLNSTRSGGKRGSTPVDAVRDQLSADLVAAQSLQQFVGRDEYEQVAEVISEQNQLLPGGAERNTSRMVAGLLPPWRREGMGREMIEHLVGKIQGWLRNLCDSVKGTSGGDVQKVFGGEEHDGSDGIVAAPFCPAVKRAHRSMVQKSLFHDLVVPSTDIWSGRAYQVCEGLRTQTPTIHFEYVTDESVRPVFHLSCLHYIDGGEMPMSAVVQEAQKRRSLVIHIDYVRFRPSSPPHSDKTTDHQMRARGGNPTRDAVVGVPTASVSSGANAGGGEGRAAAAPVNFSPHDELVSSILDNYEPYRMMELNLLPHLKNRTFYEDQLRSLRSHRSLTEEQRRLMITLEKLHKLTCKLQHSYLSGMVTSWRQLLQLGRGNFGGISTSSEQPDTEGRRREFFAAHVSPFQVSMNGTTNSFGSPSGFIIGNGESASMLVDPSVTAEVQRNACFHLYLKREGSKVDAHTVKDDRLLDYSPVIEGLTLPVGTQDEPAQHFQVLLFARTNAFTQPQFVGATEPRVINAVKVVFFNETFELHTLSDPEEILLHVIAVGGVNNRRVVTTIRMEPSLTQACLLLPMQRPIPFTHSGHSHKKYEGSVISGTACISTNWTTHHGMAMHEIEDLFLNGDADPMDPKYRPLLNTLKDHYAVSKTQTAVSVNGVSKTGANAGDNVVPQVGRVVGPEPALYKGLPTRHPKESKRLQQLRHRWAIRLNREEPRDAAEAHLFSQPIPLDDSDSSDFAAACKHCVENREFMQTAPDELHEGFVQGSSPSCLSLSLLSRREKLKLWQQRLRFQKSKYTNSRKVEDHEIQERHVIIPKLLPAKPIHWTAESQLNPRRGKRPKIRDISPDSLAVLRDSRIVVHIMRASTLPVRSDGTPLEPFIEVSFVYETVHSRSEVGSTPSWFETLNIPFSPPDFDDDTLSLIDDDIVISVYDKVEIPMPPTTITAGVISHETHYRTERRLLGVLRVPFYSLYTAEQARMEGLYVLTTPRWSLGYHQSPREVSHGDSGRVKLRRRGLPSLLPTIQLYLALWPQPDRGSREAGDELEMQRLVKQFNVSPQLRYLHETAMRWRPSALSKIRKLSSVNPVARNRSISPFVLCTTGDLTLVCRFLLAGGGPPPITVTTVSQAIRFVSLLPLRLDMLPVQSNRAWNTNVEVLKARECKYEELSLLLAHFLRFIEPSEATYVVTGRGPIYQRVTMVLHSFDGELRLIDPHGGVVAPVHDPNFNFFTDVDMVVSHDQLWANIQISGTPHRMDWNLHDERFWFPCFNHEDENVRACLPFIAAIQRETLQFSLRDTGKEREIEHELQINVRRALVRWRNGKKPAFHHGVAAALQKLLEEAESERLVWANMSQERVNRRAARHLNEYLGEEVMHDSRRPGHTPCASHSLAVGNPCLRMAGSPINCAYMPNDTGHRLILQRVFETAVHEAAANDVSFAVATYVRGYTREVFSMWVFLAALYRV
Protein: Leucine-rich repeat protein kinase family protein (Leucine-rich repeat receptor-like protein kinase) (C0LGM1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Uncharacterized protein F7J8_130
- Calcium-binding EF hand family protein
- SNF1-related protein kinase regulatory subunit beta-3
- Glycoside hydrolase family 28 protein/polygalacturonase family protein
- At2g23910
- Cation/H
- Cellulose synthase-like protein B1
Sequence:
MVRISLLLLCLLVSTCLFTSSSAQAPGFVSLDCGGAEPFTDELGLKWSPDNHLIYGETANISSVNETRTQYTTLRHFPADSRKYCYTLNVTSRNRYLIRATFLYGNFDNSNNVYPKFDISLGATHWATIVISETYIIETAELVFLASSPTVSVCLSNATTGQPFISTLELRQLSGSMYGSMLSEDRFYLSVAARINFGAESEASVRYPDDPYDRIWESDLQKKPNYLVDVAAGTVRVSTTLPIESRVDDRPPQKVMQTAVVGTNGSLTYRMNLDGFPGFGWAFTYFAEIEDLAEDESRKFRLVLPEQPEYSKSVVNIKENTQRPYRVYAPGYPNITLPFVLNFRFAKTADSSRGPILNAMEISKYLRKSDGSVDATVMANVASLYSSTEWAQEGGDPCSPSPWSWVQCNSDPQPRVVAIKLSSMNLTGNIPSDLVKLTGLVELWLDGNSFTGPIPDFSRCPNLEIIHLENNRLTGKIPSSLTKLPNLKELYLQNNVLTGTIPSDLAKDVISNFSGNLNLEKSGDKGKKLGVIIGASVGAFVLLIATIISCIVMCKSKKNNKLGKTSAELTNRPLPIQRVSSTLSEAHGDAAHCFTLYEIEEATKKFEKRIGSGGFGIVYYGKTREGKEIAVKVLANNSYQGKREFANEVTLLSRIHHRNLVQFLGYCQEEGKNMLVYEFMHNGTLKEHLYGVVPRDRRISWIKRLEIAEDAARGIEYLHTGCVPAIIHRDLKTSNILLDKHMRAKVSDFGLSKFAVDGTSHVSSIVRGTVGYLDPEYYISQQLTEKSDVYSFGVILLELMSGQEAISNESFGVNCRNIVQWAKMHIDNGDIRGIIDPALAEDDYSLQSMWKIAEKALLCVKPHGNMRPSMSEVQKDIQDAIRIEKEALAARGGISDEFSRSSAHSSSLNMGMLDLAGSQSYVSIDESVLQPTAR
Protein: Protein ASPARTIC PROTEASE IN GUARD CELL 1 (AtASPG1) (EC 3.4.23.-) (Q9LS40)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Aspartic protease involved in drought avoidance through abscisic acid signaling.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:22268147}.
Interaction partners:
- Membrane metalloprotease ARASP, chloroplastic
Sequence:
MAFPRFLSLLAVVTLSLFLTTTDASSRSLSTPPKTNVLDVVSSLQQTQTILSLDPTRSSLTTTKPESLSDPVFFNSSSPLSLELHSRDTFVASQHKDYKSLTLSRLERDSSRVAGIVAKIRFAVEGVDRSDLKPVYNEDTRYQTEDLTTPVVSGASQGSGEYFSRIGVGTPAKEMYLVLDTGSDVNWIQCEPCADCYQQSDPVFNPTSSSTYKSLTCSAPQCSLLETSACRSNKCLYQVSYGDGSFTVGELATDTVTFGNSGKINNVALGCGHDNEGLFTGAAGLLGLGGGVLSITNQMKATSFSYCLVDRDSGKSSSLDFNSVQLGGGDATAPLLRNKKIDTFYYVGLSGFSVGGEKVVLPDAIFDVDASGSGGVILDCGTAVTRLQTQAYNSLRDAFLKLTVNLKKGSSSISLFDTCYDFSSLSTVKVPTVAFHFTGGKSLDLPAKNYLIPVDDSGTFCFAFAPTSSSLSIIGNVQQQGTRITYDLSKNVIGLSGNKC
Protein: Serine protease inhibitor Kazal-type 7 (Esophagus cancer-related gene 2 protein) (ECRG-2) (Q6IE32)
Organism: Mus musculus (Mouse)
Function: Probable serine protease inhibitor.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MKLVGGLLLLFAATYVCNCSEVTSHPSATVDCDIYKKYPVVAIPCPIVNIPVCGSDYITYGNKCKLCTEILRSNGKIQFLHEGHC
Protein: 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Q9BHK7)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR006743}.
Interaction partners:
- mRNA-decapping enzyme 1
- m7GpppN-mRNA hydrolase dcap-2
- U6 snRNA-associated Sm-like protein LSm1
- FHA domain-containing protein
- 5'-3' exoribonuclease 2 homolog
- Protein PAT1 homolog 1
- m7GpppX diphosphatase
- Probable exosome complex exonuclease RRP44
- PIN domain-containing protein
- Helicase SKI2W
Sequence:
MGVPKFYRWTSERYPCLSEVINESQIPEFDNLYLDMNGIIHNCSHPNDDDVTFRITEDEIFVNIFAYIENLYNLIRPQKVFFMAVDGVAPRAKMNQQRARRFMSARTAHTQLAKALENGEIMPSEARFDSNCITPGTYFMTRLHQKLDDWIKTKSATDSRWQGRKIILSGHNVPGEGEHKIMDFIRTERAGSSYDPNTRHCMYGLDADLIMLGIVSHEPHFSLLREEVTFNTRPRKNDNKATKKPKRTDSDVKKFHLLHLSLLREYLAWEFADVKDSLPFEYEMERIVDDWILLGLLVGNDFLPHLPNIHIHDDALPLLYSTYKKVLPTLDGYINEAGYLNLSRFEAFLAELALNDKTSFMERLEDEQFMESKRIRVVDPEQQELAEPELVAFESSDVEDEAGAEESKDEAGGAGAEDDEDDAAFVSDHEEDGDDLEPGSGSDELLLSNLDAQLLEDEFNDELATLALSGMNDADFANDVEACWTKTINNQFKRHKKTYYSDKLRYKNISKQQLREQAEGYVRAIQWNLHYYYHGCVSWSWFYPHHYAPFISDVRGFVGMRMEFELSEPFHPFEQLLAVLPEASADCLPRPLRELMSSDPAKSPICDFYPANFETDLNGKRNEWEAVVLIPFIEEKRLLEAIEAKRSRLTSEENARNSHGSHIQCISSPEPPNSQGQWRTVRSEIPQDSFRIPRSQVKWGLLPNVKMDVYFPGFPTMKHLSHLGELRFANCNIFGMASRKESMVLKVENERAHTDIIELGSELCDEEVCIDWPILKVAKIDSIWGGDDKIVRKCDDEIIVKDMSEEEKRQWQAHANQLTEHLMTRFAIEIAAQKDSKGKHIRPAVAWVRKFTGLVYEAQGGGKEPSVLKACKQWSSPQQLMPVLLPLVVKDVLLENSRVLADLPMKQAYPKQSIVWITDPKFALFGMPGMVNGFSNEKSADCRIEVIGMSTQNKVDKMEALRKKMEQKSLRWMGGYDCARQCQVDTRLFARITGTMFLWNEPRERVEKGQQISSSDSKINCGLALKYSRRDLCVADYTDRTEHTNQRGVTNKVWFYTNLATRLVSEYRRKFPDVWKYLETIGLTQQDDVYYTEDIWSNEKTREKRFGELSEFLGGLPSLEAEQLKCGTVYADRQLITEIEMILAEPDEKKPVMNKYMMAPGALFRYELYNGKVHADPAADFQILDRVALMSSDTKVPKTTQGTVVGIHDDKIDVFFDKPFDGGQKVRGSNEAAAIRVPQSALLNVTFGIVRKNVQHKKQVEKALTGAYVPMPAQKNSAKNEPAPSTSSSNSNSTNNKKNSSKKEKNKQKPTKTDEESPEALTDSLNKLLKIKPPSAEATSGKQVSLMELLGGGGAAGAKKPAQNAKTLAEIESDSSQSASKSSILQQLSAAQKAAAPKPKKEASQKKQKPQAAPPQKVEILRKPTPPPPPPAEEQKPAPAPFGAPTPPPQFPFGPQPLQFAPHPMMMMGYPMGMPMGMPIGGPHHYQQQQNQQEKRANHPTLTDFKPSAVHRRQNCHQRPSNQPPKVTMITKRTSSPTPPEKEEDAAPRALPSSPPPPSKSAAEEKTTTKKPRKKKQSRLGSNFSNPTASS
Protein: SIS domain protein (Q9A8Q6)
Organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus)
Interaction partners:
- IolC protein
- IolD protein
- IolB protein
- IolE protein
- methylmalonate-semialdehyde dehydrogenase
- Sugar ABC transporter, permease protein
- Myo-inositol 2-dehydrogenase
- Sugar ABC transporter, periplasmic sugar-binding protein
- ABC transporter, HlyB/MsbA family
Sequence:
MSEDTAAASPPASAEELRSAILERYDSLSKRLQQIARYVLDEPNELALETLAVISERCGVQPSAIVRFAKTFGYPGASQMQRLFRDGLLSGHAGLGYSERVRHFNEAVAMTPQGGADVLAEFVEGNTLALQNLGQTVSAADMAKAVSLIDKAETVYVAGFRRSFPVASYLAYSLQQANKRTLFIDGVAGLTKQQVQTIGPKDLLIAVSYHPYAEETVMAAEMATQRGAKILSISDSLVSPIAKPAELVLHVRESEVRTFRSLAASICLAQALVIGFAFEAGKEERKAQKAG
Protein: Pfmc-2TM Maurer's cleft two transmembrane protein (C6KTE8)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MFHYIYKIYIFTIILCASNLFNNNVVEIGTYKLSYHNGGIQFRMLAQKNTNKKPFGNTLTNILCKDKKKKNLDPQISSLVSLVDNMDITQEKKDKIKNLSLKYINSRDVKEKNESINELQKYSNNEECKEQMDSYLMHLRMQNDIKCLKRKNLWNNIGINSITLSLIIIMIMIACMFAIYSTAQYIYVPASFLLIFIIYIVARYFPDMKIGFKKLKTKLNTFFQNKKQITK
Protein: Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (G3V0E4)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}.
Interaction partners:
Sequence:
MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGKPGFFSSMQKVGQVLLINSSF
Protein: Late embryogenesis abundant protein 29 (LEA 76 homolog) (Q9LW12)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved dehydration tolerance.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:25005920}.
Interaction partners:
- Late embryogenesis abundant protein 18
- Late embryogenesis abundant protein 46
- Late embryogenesis abundant domain-containing protein / LEA domain-containing protein
- Late embryogenesis abundant protein 6
- Late embryogenesis abundant protein ECP63
- 12S seed storage protein CRA1
- Late embryogenesis abundant protein
- Alpha/beta-Hydrolases superfamily protein
- Probable desiccation-related protein LEA14
- AT1G27990 protein
Sequence:
MASNQQSYKAGETRGKAQEKTGQAMGTMRDKAEEGRDKTSQTAQTAQQKAHETAQSAKDKTSQTAQAAQQKAHETAQSAKEKTSQTAQTAQQKAHETTQAAKEKTSQAGDKAREAKDKAGSYLSETGEAIKNKAQDAAQYTKETAQGAAQYTKETAEAGRDKTGGFLSQTGEHVKQMAMGAADAVKHTFGMATEEEDKEHYPGSTTTTTATTRTTDPTHQTYQRK
Protein: Beta-amylase 8 (EC 3.2.1.2) (1,4-alpha-D-glucan maltohydrolase) (Beta-amylase 2) (Q9FH80)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic
- 4-alpha-glucanotransferase DPE2
- alpha-D-xyloside xylohydrolase
- Isoamylase 3, chloroplastic
- Heteroglycan glucosidase 1
- Probable alpha-amylase 2
- Alpha-glucan phosphorylase 2, cytosolic
- Alpha-amylase 1
- Alpha-amylase 3, chloroplastic
- Isoamylase 2, chloroplastic
Sequence:
MHTLNNTITTTTGSQDPNLDPIPDPDQFPNRNRNQPQSRRPRGFAAAAAAASIAPTENDVNNGNIAGIGGGEGSSGGGGGGGGKGKREREKEKERTKLRERHRRAITSRMLAGLRQYGNFPLPARADMNDVIAALAREAGWSVEADGTTYRQSQQPNHVVQFPTRSIESPLSSSTLKNCAKAAIESQQHSVLRNDEKLAPVSLDSIGIAESDHPGNGRYTSVSPITSVGCLEANQLIQDVHSAEQCNDFTESFYVPVYAMLPVGIIDNFGQLVDPEGVRQELSYMKSLNVDGVVIDCWWGIVEGWNPQKYVWSGYRELFNLIRDFKLKLQVVMAFHEYGGNASGNVMISLPQWVLKIGKDNPDIFFTDREGRRSFECLNWSIDKERVLHGRTGIEVYFDFMRSFRSEFDDLFVEGLITAVEIGLGASGELKYPSFPERMGWIYPGIGEFQCYDKYSQLSLQKEAKSRGFTFWGKGPENAGQYSSHPHETVFFQERGEYDSYYGRFFLNWYSQLLIGHAENVLSLANLAFEETKIIVKIPAIYWSYKTASHAAELTAGYYNPSNRDGYSLVFETLKKYSVTVKFVCPGPQMSPNAHEEALADPEGLSWQVINAAWDKGLQIGGENAITCFDRDGCMRLIDIAKPRNHPDGYHFSFFTYRQPSPLVQGSTCFPDLDYFIKRMHGDIRDKQF
Protein: Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (PTR1 protein) (Transin-1) (P03957)
Organism: Rattus norvegicus (Rat)
Function: Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted {ECO:0000269|PubMed:1963430, ECO:0000269|PubMed:1988438, ECO:0000269|PubMed:2841336}.
Interaction partners:
- Metalloproteinase inhibitor 1
- Osteopontin
- Metalloproteinase inhibitor 2
- Stromelysin-2
- Matrilysin
- Metalloproteinase inhibitor 3
- Aggrecan core protein
- Collagenase 3
- A disintegrin and metalloproteinase with thrombospondin motifs 4
- Interleukin-6
Sequence:
MKGLPVLLWLCTAVCSSYPLHGSEEDAGMEVLQKYLENYYGLEKDVKQFTKKKDSSPVVKKIQEMQKFLGLKMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKNHISYRIVNYTLDLPRESVDSAIERALKVWEEVTPLTFSRISEGEADIMISFAVEEHGDFIPFDGPGMVLAHAYAPGPGTNGDAHFDDDERWTDDVTGTNLFLVAAHELGHSLGLFHSANAEALMYPVYKSSTDLARFHLSQDDVDGIQSLYGPPTESPDVLVVPTKSNSLDPETLPMCSSALSFDAVSTLRGEVLFFKDRHFWRKSLRTPEPGFYLISSFWPSLPSNMDAAYEVTNRDTVFILKGNQIWAIRGHEELAGYPKSIHTLGLPETVQKIDAAISLKDQKKTYFFVEDKFWRFDEKKQSMDPEFPRKIAENFPGIGTKVDAVFEAFGFLYFFSGSSQLEFDPNAGKVTHILKSNSWFNC
Protein: Reticulon-like protein B2 (AtRTNLB2) (VirB2-interacting protein 2) (Q9SUT9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:17604024}; Multi-pass membrane protein {ECO:0000269|PubMed:17604024}.
Interaction partners:
- Reticulon-like protein B18
- Reticulon-like protein B21
- AT4g33900 family protein)
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
- At1g13195
- AT5g37540/mpa22_p_70
- Reticulon-like protein B17
- Extracellular ligand-gated ion channel protein
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3
- Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC
Sequence:
MADEHKHEESSPNLDPAVEVVERESLMEKLSEKIHHKGDSSSSSSSDDENEKKSSSSSPKSLKSKVYRLFGRERPVHKVLGGGKPADIFMWKDKKMSGGVFGGATVAWVLFELMEYHLLTLLCHVMIVALAVLFLWSNATMFIHKSPPKIPEVHIPEEPLLQLASGLRIEINRGISSLREIASGRDIKKFLSAIAGLWVLSILGGCYSFLTLAYIALVLLFTVPLFYDKYEDKVDSYGEKAMAELKKQYAVLDAKVFSKIPRGPLKDKKKD
Protein: DDB1 and CUL4 associated factor 17 (F5H7W1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGPTRKPNVCSRLSRRALGCFSRDAGVVQRTNLGILRALVCQESTKFKNVWTTHSRSPIAYERGRIYFDNYRRCVSSVASEPRKLYEMPKCSKSEKIEDALLWECPVGDILPNSSDYKSSLIALTAHNWLLRISATTGKILEKIYLAPYCKFRYLSWDTPQEVIAVKSAQNRGSAVARQAGIQQHVLLYLAVFRVLPFSLVGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQTIAEQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDMPPLLFEVSSLENAFQIGGHPWHYIVTPNKKKQKGVFHICALKDNSLNENVLTVTASGRVVKKSFNLLDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLVESWDVTYSHEVYFDRDLVLHIEQKPNRVFSCYVYQMICDTGEEEETINRSC