wanglab/gogpt-training-data huggingface dataset:
Protein: GH23382p (Neuropeptide F-like receptor) (Short neuropeptide F receptor, isoform A) (Short neuropeptide F receptor, isoform B) (Q9VW75)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Short neuropeptide F
- Neuropeptide F
Sequence:
MANLSWLSTITTTSSSISTSQLPLVSTTNWSLTSPGTTSAILADVAASDEDRSGGIIHNQFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCFNPSNNNIINITRGYNRSDRNTCGPRLHHGKGDGGMGGGSLDADDQDENGITQETCLPKEKLLIIPREPTYGNGTGAVSPILSGRGINAALVHGGDHQMHQLQPSHHQQVELTRRIRRRTDETDGDYLDSGDEQTVEVRFSETPFVSTDNTTGISILETSTSHCQDSDVMVELGEAIGAGGGAELGRRIN
Protein: STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2) (Q9C0K7)
Organism: Homo sapiens (Human)
Function: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:14517248}. Cytoplasm {ECO:0000269|PubMed:14517248}.
Interaction partners:
- Calcium-binding protein 39
- Serine/threonine-protein kinase STK11
- Calcium-binding protein 39-like
- Trafficking kinesin-binding protein 2
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- STE20-related kinase adapter protein alpha
- DDB1- and CUL4-associated factor 12
- Translocation protein SEC63 homolog
- Protein transport protein Sec61 subunit gamma
Sequence:
MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF
Protein: General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) (Q12789)
Organism: Homo sapiens (Human)
Function: Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element.
Subcellular location: Nucleus.
Interaction partners:
- General transcription factor 3C polypeptide 2
- Transcription factor TFIIIB component B'' homolog
- General transcription factor 3C polypeptide 5
- General transcription factor 3C polypeptide 4
- General transcription factor 3C polypeptide 3
- Transcription factor IIIA
- Transcription factor IIIB 90 kDa subunit
- General transcription factor 3C polypeptide 6
- TATA-box-binding protein
- Gamma-butyrobetaine dioxygenase
Sequence:
MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPCTQEFLWRALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVALEDVYPIHMILENKDGIQGSCRYFKERKNITNDIRTKSLQPRCTMVEAFDRWGKKLIIVASQAMRYRALIGQEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSVMLSTRTNHIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLRLQEIHPECGPCKTKKGTDVMVRCLKLLKEFKRNDHDDDEDEEVISKTVPPVDIVFERDMLTQTYDLIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYQREKARSELLTTVSLASMQEESLLPEGEDTFLSESDSEEERSSSKRRGRGSQKDTRASANLRPKTQPHHSTPTKGGWKVVNLHPLKKQPPSFPGAAEERACQSLASRDSLLDTSSVSEPNVSFVSHCADSNSGDIAVIEEVRMENPKESSSSLKTGRHSSGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIVRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKTSQPPVPQGEAEEDSQGKEGPSGSGDSQLSASSRSESGRMKKSDNKMGITPLRNYHPIVVPGLGRSLGFLPKMPRLRVVHMFLWYLIYGHPASNTVEKPSFISERRTIKQESGRAGVRPSSSGSAWEACSEAPSKGSQDGVTWEAEVELATETVYVDDASWMRYIPPIPVHRDFGFGWALVSDILLCLPLSIFIQIVQVSYKVDNLEEFLNDPLKKHTLIRFLPRPIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFIFLKKNAVIVDTTICDPHYNLARSSRPFERRLYVLNSMQDVENYWFDLQCVCLNTPLGVVRCPRVRKNSSTDQGSDEEGSLQKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINQAKKENTAAENGLTVRLQTFLSKRPMPLSARGNSRLNIWGEARVGSELCAGWEEQFEVDREPSLDRNRRVRGGKSQKRKRLKKDPGKKIKRKKKGEFPGEKSKRLRYHDEADQSALQRMTRLRVTWSMQEDGLLVLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAYLNYKVCLAEVYQDKALVGDFMNRRGDYDDPKVCANEFKEFVEKLKEKFSSALRNSNLEIPDTLQELFARYRVLAIGDEKDQTRKEDELNSVDDIHFLVLQNLIQSTLALSDSQMKSYQSFQTFRLYREYKDHVLVKAFMECQKRSLVNRRRVNHTLGPKKNRALPFVPMSYQLSQTYYRIFTWRFPSTICTESFQFLDRMRAAGKLDQPDRFSFKDQDNNEPTNDMVAFSLDGPGGNCVAVLTLFSLGLISVDVRIPEQIIVVDSSMVENEVIKSLGKDGSLEDDEDEEDDLDEGVGGKRRSMEVKPAQASHTNYLLMRGYYSPGIVSTRNLNPNDSIVVNSCQMKFQLRCTPVPARLRPAAAPLEELTMGTSCLPDTFTKLINPQENTCSLEEFVLQLELSGYSPEDLTAALEILEAIIATGCFGIDKEELRRRFSALEKAGGGRTRTFADCIQALLEQHQVLEVGGNTARLVAMGSAWPWLLHSVRLKDREDADIQREDPQARPLEGSSSEDSPPEGQAPPSHSPRGTKRRASWASENGETDAEGTQMTPAKRPALQDSNLAPSLGPGAEDGAEAQAPSPPPALEDTAAAGAAQEDQEGVGEFSSPGQEQLSGQAQPPEGSEDPRGFTESFGAANISQAARERDCESVCFIGRPWRVVDGHLNLPVCKGMMEAMLYHIMTRPGIPESSLLRHYQGVLQPVAVLELLQGLESLGCIRKRWLRKPRPVSLFSTPVVEEVEVPSSLDESPMAFYEPTLDCTLRLGRVFPHEVNWNKWIHL
Protein: Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4) (A5PKP9)
Organism: Xenopus laevis (African clawed frog)
Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Regulates pronephros development, possibly by promoting ubiquitination and thus inactivation or degradation of map3k10/mlk2.
Interaction partners:
Sequence:
MALKRIQKELMDLQRDPPAQCSAGPVGEDLFHWQATIMGPNDSPFQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWTQKYAM
Protein: Fimbrial subunit CupA4 (Q9I1Y4)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Usher CupA3
- Chaperone CupA5
- Chaperone CupA2
- Chaperone CupB4
- Fimbrial subunit CupA1
- Chaperone CupC2
- Fimbrial subunit CupB6
- EAL domain-containing protein
- Usher CupC3
Sequence:
MNRTLPLLPALALGVLLGLPASGQATCYRVTSVGSETTTSNTQIRPGEGTAGSWTGACDTCNGSLGLPSVVNVSDESFQPYPTLIASAVAPLTQYGATGGYDPERVFFRCSAGDAVYEMFSTNGDDLYSGYYTGADTVGNDIGLQDAYRTAWPNVLLRLTNVETGETITPIWKERQLSGLDIDSRGFQLVKAKNLAAVRAELYSAPLEAIRYYSPTILSQPYSYTQPAAYIAIKGPGLTAPTVGQAHVGGNWGGWYSNWPGAIGLYRYVTLKRYPTCAVMTVTPHVQFPSITLAEIDSGGVREAPFELTFKCQSGMTNGTGAGATALGIRVSSGALAASPALGLVNASGGLSYLLSDRYGEPGIARGVGIRIYRDGTPMTLLANENSAGGSNAEATGWYPAIGGATQANGGSGGIDLYRETFRARLEKLALGSQPGVTAGRVEATAQVVIRVQ
Protein: Outer membrane protein Slp (P37194)
Organism: Escherichia coli (strain K12)
Function: The induction of Slp may help to stabilize the outer membrane during carbon starvation and stationary phase.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:16079137}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:16079137}.
Interaction partners:
- Glutamate decarboxylase alpha
- Protein HdeD
- HTH-type transcriptional regulator DctR
- Transcriptional regulator GadE
- Acid stress chaperone HdeA
- Acid stress chaperone HdeB
- Putative magnesium transporter YhiD
- Glutamate/gamma-aminobutyrate antiporter
- Glutamate decarboxylase beta
- HTH-type transcriptional regulator GadW
Sequence:
MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQPGLYVGQQARFGGKVINVINGKTDTLLEISVLPLDSYAKPDIEANYQGRLLARQSGFLDPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYGYGAFWPEPGWGAPYYTNAVSQVTPELVK
Protein: Uncharacterized protein C119.09c (O42901)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Serine palmitoyltransferase 1
- Serine palmitoyltransferase 2
- Sphingosine N-acyltransferase lag1
- Cytoskeletal signaling protein slm1
Sequence:
MGSSSSRRRSSSLVTKVPKPTIDDRLDQGSATNYNSNWVNYKGAWVIHIVLIAALRLIFHAIPSVSRELAWTLTNLTYMAGSFIMFHWVTGTPFEFNGGAYDRLTMWEQLDEGNQYTPARKYLLVLPIILFLMSTHYTHYNGWMFLVNIWALFMVLIPKLPAVHRKRIFGIQKLSLRDDDNDSIPR
Protein: Small ribosomal subunit protein uS11m (37S ribosomal protein S18, mitochondrial) (O13882)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:P42847}.
Interaction partners:
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein uS19m
Sequence:
MVLKHSVTYNLSFFISFTFSSIFFSSLILFLVYKSVLSKLFFIKYLMLNLTKVGLRRFWSQSPRRNAPKKELSSLLESTITPKAFSKRTEEPNPIMQGTDTIPMPFYLHAKCLKNNTHITLCSPERKIIFRASGGTCGFRKGKRRGYDAAYTICSKVLEQIQVKRLGIENLHVIFHGFSQAREAVQNCLLGQEGAVIRDKIVKVMDRTPIKFGGPRGRRERRI
Protein: 2'-5'-oligoadenylate synthetase 3 (F8VS35)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDLYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKGGSSGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVPGLRLTFPEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNSGCQGGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVKPLGRVSPDM
Protein: DNA topoisomerase I (EC 5.6.2.1) (DNA topoisomerase 1) (Q5BGS7)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- DNA topoisomerase 2
- Tyrosyl-DNA phosphodiesterase, putative
- Ubiquitin-like domain-containing protein
- SUMO-conjugating enzyme UBC9
- SWIB/MDM2 domain protein
- Ribonuclease
- Uncharacterized protein
- DNA polymerase epsilon catalytic subunit A
- Topoisomerase 1-associated factor 1
- 3'-5' exonuclease/helicase
Sequence:
MSSSDDDTPLVKMNGRSSGGQSDVKVNGAADTNGHVDPGVSIRFGPVQKDEDVEMNDANGASASKRKARSSANQAQSYAEPESSEEDEPLSKRRRTSVKHEDPETDDDVPLALNGRKLPKASETAIGEESDSDVPIERKLAAEKKKIQVKGEKDADPSAQATKSAASGKKQANGVKKEPASAKQTLKQVKAEPKSAQSTPAKKNAKATALKKEESEEAEEPEEEEYRWWEDPTKGDGTIKWTTLEHNGVVFPPPYEPLPKHVKMKYDGIPVDLHPEAEEVAGFFGSMLNSTQHTENPTFQKNFFADFKEILKKTGGAKDQKGNKVDIKEFSKCDFQPIFQYYDAQRQEKKALPPAEKKRLKAEKDAQEAPYMYCMWDGRKQKVGNFRVEPPSLFRGRGEHPKTGRVKARVQPEQITINIGKEARVPPPPEGHKWKEVKHDQEGTWLAMWQENINGNYKYVMLAANSDVKGQSDYKKFEKARELKKHIARIRKDYQKNLKHELMVERQKATAVYLIDQFALRAGNEKGEDEAETVGCCSLKYENVTLKPPNKVIFDFLGKDSIRFYDEVEVDPQVFKNLKIFKKPPKKEGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLKSMHATGNNAEKVKAYNDANRKVAILCNHKRTVGAAHAHQMEKMSERIKGQRYQKWRLKQMMLDLDPSLKKKKGAQFFELDEDIDKEWIKEHQAFLIEEQAQKIKKKFEKDNEKLLAEGEKEMKASELETRLEAVKELEKKFNKENKTGKVEAEGRSPTVEKLEASITKLQQRIENMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFKVPIEKFFSKSLREKFEWAIKSVDENWEF
Protein: 60S ribosomal protein L17 (AFU_orthologue AFUA_1G14410) (Q5BFA4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- 60S ribosomal protein L28
- 60S ribosomal protein L31e
- 40S ribosomal protein S26
- 60S ribosomal protein L22, putative
- 40S ribosomal protein S14
- RL16_NEUCR 60S ribosomal protein L16Ribosomal protein L16a
- Ribosomal protein
- Small ribosomal subunit protein eS19
- Uncharacterized protein
- 60S ribosomal protein L9, putative
Sequence:
MVRYAAQDIPAAKSARARGSYLRVSFKNTRETAQAINGMKLQRALAFLENVKTKTEVVPFRRFASSTGRCAQAKQWGVARARWPVKSAEFLLDLLKNAEANADTKGLDTGNLVVKHIQVNQAPKGRRRTYRAHGRINPYMTNPCHIELILTEGEEEVKKATVVERTRLSSRQRGAQIRKALTSA
Protein: AT3g29240/MXO21_9 (PPR containing protein (DUF179)) (Q9LS71)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alanine-tRNA ligase, putative
- At1g32160/F3C3_6
- Pentatricopeptide repeat
- At5g52960
- At4g33110
- At1g63610
- ARM repeat superfamily protein
- Uncharacterized protein At3g49140
- MAR-binding filament-like protein
- UV-B-induced protein At3g17800
Sequence:
MDACFLTSRSISGVKELVPFIKARIFTCPKRNSGQFVTRKVASPISVNCSLSDSWKPLEDDADLFKDCVNNSTSDADWREFRARLVAGEQAATSEKDQPSWSNPDMVVDYQPSSSSLITIGSKWAHKIHEPETGCLLIATEKLDGVHIFEKTVILLLSVGPSGPIGVILNRPSLMSIKETKSTILDMAGTFSDKRLFFGGPLEEGLFLVSPRSGGDNEVGKSGVFRQVMKGLYYGTRESVGLAAEMVKRNLVGRSELRFFDGYCGWEKEQLKAEILGGYWTVAACSSTVVELGSAVQSHGLWDEVLGLIGPQTGSVI
Protein: DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (G3H0N9)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (By similarity). Required for survival of B-cell progenitors and normal antibody production (By similarity).
Subcellular location: Endoplasmic reticulum lumen {ECO:0000250|UniProtKB:Q9QYI6}.
Interaction partners:
- Endoplasmic reticulum chaperone BiP
- Hypoxia up-regulated protein 1
- X-box-binding protein 1
- Nucleotide exchange factor SIL1
- Heat shock cognate 71 kDa protein
- Heat shock cognate 71 kDa protein
- Heat shock 70 kDa protein 1-like
- Heat shock 70 kDa protein 1A/1B
- Heat shock cognate 71 kDa protein
- Heat shock 70 kDa protein 1A
Sequence:
MATPQSVFVFAICILMITELILASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDAHRRKEYDTVGHTAFTNGKGQRGSGSPFEQSFNFNFDDLFKDFNLFGQNQNTRSKKHFENHFQTHQDGSNRQRHHFQEFSFGGGLFDDMFEDMEKMFSFSGFDTTNRHTVQTENRFHGSSKHCRTVTQRRGNMVTTYTDCSGQ
Protein: Peptidoglycan recognition protein 5 (Q1W1Y2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MQHSFFIFLYTGAEFLHETGKYAEVHVCCPSLSSRANKPVSLVMLEHTGNEKFVADMDGHTNTVDINADTVSRRGWDAVQPREMTQMESPAHTVIVHHTALRFCAHPRESVTELAHIQRMHMQERGFDDIGYNFLISGDGTVYEGRGWGIVGAHAKEHNFYSVGIAFMGNLNADLPSSASLSALLRLLHIGVLHGHVRPNFVLLGHKDVAKTACPGENLYSVLPKLRDRLQNNELLQA
Protein: Myosin IE heavy chain (Q03479)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. May play a role in moving membranes relative to actin.
Interaction partners:
- Major actin
Sequence:
MIPKTKAEGVPDFVLLNQITENAFIENLTMRHKSDNIYTYIGDVVISTNPFKNLNIYKESDIKAYNGRYKYEMPPHIYALANDAYRSMRQSQENQCVIISGESGAGKTEASKKIMQFLTFVSSNQSPNGERISKMLLDSNPLLEAFGNAKTLRNDNSSRFGKYMEMQFNAVGSPIGGKITNYLLEKSRVVGRTQGERSFHIFYQMLKGLSQSKLNELGLTPNAPAYEYLKKSGCFDVSTIDDSGEFKIIVKAMETLGLKESDQNSIWRILAAILHIGNITFAEAAEQRTGTTTVKVSDTKSLAAAASCLKTDQQSLSIALCYRSISTGVGKRCSVISVPMDCNQAAYSRDALAKALYERLFNWLVSKINTIINCTTEKGPVIGILDIYGFEVFQNNSFEQLNINFCNEKLQQLFIELTLKSEQEEYVREGIEWKNIEYFNNKPICELIEKKPIGLISLLDEACLIAKSTDQTFLDSICKQFEKNPHLQSYVVSKDRSIGDTCFRLKHYAGDVTYDVRGFLDKNKDTLFGDLISSMQSSSDPLVQGLFPPTRPEDSKKRPETAGSQFRNAMNALITTLLACSPHYVRCIKSNDNKQAGVIDEDRVRHQVRYLGLLENVRVRRAGFAGRIEYTRFYNRYKMLCKKTWPSFNGTAKQATELILQQHNIDKEEIRMGKTKVFIRNPTTLFYFEEKRELEMPRIVTLIQKTWRGYRARSKWNQRKAAIKIQLFYRSYRYKKWFRELHRAFKDVARDPQWGKQVFWPKHPSILDRAVQLTHKIHNCWRAEKMILSLGAGQNHMRQKVMAYDIFHGKKKWDFRRHFDADYLEKPSNPNQQKYVLAMQNLFSTYGDTEVLFADYVIKVNPKGVPQRRGIVVTGTNIYKHDPKNYKVKKWGTPLVDVTSISISPMADTFLVLHCKAPQRDFVLDLGCNGYEAVSEITTVIVQQVLKLTGVKLSVQFTSSITYNNARPKGSDTILTFAPINNDPKLIGSQFKKGKGNQATIQFKD
Protein: Suppressor of smlA (Protein secondary enhancer of smlA) (P0DJ29)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in regulation of group size of aggregation streams.
Interaction partners:
- GH16 domain-containing protein
- EGF-like domain-containing protein
- Small aggregate formation protein
- RBR-type E3 ubiquitin transferase
Sequence:
MRNEEAEKLFWIFNNKVRPINYSEIVENTTPRKSSINREKIESENNGQVYNELFFFKLLLNEDLSKFLISLINTNLRHEREKKLDKGKDISRLNDLTDITFWKFITDYLKNIYSNKNNDKIPPELINLKMMDHNRYSAVHNVLDMKSHRFEEYCEIFMNSALKYINIGNVLNCDETIYAYYGKDAIKDHILINNDSKPHSVGIEAYSLTTKLNISNCPYVISYGPRTPENCQSPFNSLKTLLDNLHSKYNWEDPRNNLIVCCDSAFALVNNKECLDELKCRILSSTRKSGVTVPQEIKIFVKPLLTIHKTFLFYDESTGLLYEYTKNTAGHINCIATNLYSRYSNPYVEINNNLNIEQFATIGNLFRFSKKELELIFVGETLHGTTLEILNGKYKTNFVKPPCGPFWNEQMLKKLSAEHIAQIYNDKYKKENNNLNKNDKIKKILEPLDSTQDGGIYDKNKNYSKKELQDLKIKVIGTHQNRSQMIHDQYIFWYNLVDITDKRYYATIRGSSSHSYTKLFILGGLFDLILNSYSLHREYHEMELECKNPENQPPEIIQTINKFVESLIFQFHELKELQ
Protein: Laccase-C2 (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase C2) (Diphenol oxidase C2) (Lac C2) (Urishiol oxidase C2) (P86327)
Organism: Cerrena unicolor (Canker rot fungus) (Daedalea unicolor)
Function: Lignin degradation and detoxification of lignin-derived products (Probable). Oxidation of a broad range of substrates including mono-, di- and polyphenols, aromatic amines and methoxy-substituted phenols accompanied by reduction of oxygen to water.
Subcellular location: Secreted {ECO:0000269|PubMed:20175123}.
Interaction partners:
Sequence:
AIGPVADLDIVNDQLTDASMIKWDCLPYDVRSPNPLGTTGFAGGNYRSVPADLHLTTLADPR
Protein: UV excision repair protein RAD23 homolog (repC-binding protein A) (Q54LV1)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May play a role both in proteasomal degradation of misfolded proteins and DNA repair.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- DNA repair protein Rad4 family protein
- 26S proteasome non-ATPase regulatory subunit 4
- Transglutaminase-like domain-containing protein
- 26S proteasome non-ATPase regulatory subunit 2
- Ubiquilin
- 26S proteasome regulatory subunit 7
- Protein DDI1 homolog
- 26S proteasome regulatory subunit 8
- Golgi to ER traffic protein 4 homolog
- Ubiquitin carboxyl-terminal hydrolase
Sequence:
MKVTIKNINKEIYVFEVNGDLTVAELKNLISEKHNQTPSWQTLIYSGKILEDKRTLESYNITDSGFIVMMIKKPREAPATTPAPSTTPAPSTTSAPTTTTTAEPTPTTSSTNNTSTTTPTSVPTPTNNTPATPNPTPTTSSTPGSTSTTSPQQSSDFATGTELEATIKNITDMGFARDQVLRALRLTFNNAERAIEYLVSGNIPAANDPEDEEEMEGGGGSGDNPFEALRNHPHFNLLREAISKNPSIIPGILQQLAQTNPALVRQIQENPNEFIRLFQGDGNPGGNPGQFTLQVTQEESEAIQRLQALTGMDKSTVIEAYFACDKNEELTASYLFETADDE
Protein: TATA box-binding protein-like 2 (TBP-like 2) (TATA box-binding protein-related factor 3) (TBP-related factor 3) (Q6SJ96)
Organism: Homo sapiens (Human)
Function: Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14634207}. Nucleus {ECO:0000269|PubMed:14634207}. Note=Present in the cytoplasm during cytokinesis. {ECO:0000269|PubMed:14634207}.
Interaction partners:
- Transcription initiation factor IIB
- Transcription initiation factor TFIID subunit 3
- TATA box-binding protein-like 1
- Transcription initiation factor TFIID subunit 6
- Myoblast determination protein 1
- TATA-binding protein-associated factor 172
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 12
- Nuclear transcription factor Y subunit alpha
Sequence:
MEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA
Protein: Guide RNA binding protein (Q382K8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Mitochondrial RNA binding protein 1
Sequence:
MLRRIISQQTTLIRKPLGAALFATSALRLEAASSSDADGKEVGSSGEGNRATGGKWRRPSLAQQRARRAQLPPAFDVVHWNDEDISRGHLLRVLHRDTFVVLDYHRQARMLTEEGNKAERVVSVMLPAVYTARFLAVLEGRSEKVEVHSRYTNATFTPNPAAPYTFTLKCTSTRPAQQKQQVAGEEGDETFEWTVEFDVAESLMLQRFLTQALHYNTGFARTSV
Protein: Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (Ferry endosomal RAB5 effector complex subunit 2) (Fy-2) (KLRAQ motif-containing protein 1) (Q6ZMI0)
Organism: Homo sapiens (Human)
Function: Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.
Subcellular location: Early endosome {ECO:0000269|PubMed:30520571, ECO:0000269|PubMed:37267905}.
Interaction partners:
- Radial spoke head protein 3 homolog
- Quinone oxidoreductase-like protein 1
- Glutamine amidotransferase-like class 1 domain-containing protein 1
- Dystrobrevin beta
- Dystrobrevin alpha
- Ferry endosomal RAB5 effector complex subunit 3
- Homeobox protein HMX3
Sequence:
MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLIGTLTRTSDSEVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR
Protein: Peptidyl-prolyl cis-trans isomerase CYP19-2 (PPIase CYP19-2) (EC 5.2.1.8) (Cyclophilin of 19 kDa 2) (Cyclophilin-2) (Rotamase cyclophilin-6) (Q9SKQ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- UPF0235 protein At5g63440
- F-box/LRR-repeat protein At3g59200
- At1g09850
- Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic
- Probable cysteine protease RD21B
- Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic
- Probable cysteine protease RD21C
- Cysteine proteinase RD21A
- Pre-mRNA-splicing factor SYF2
- Tetratricopeptide repeat
Sequence:
MASHPKVFFDMTIGGAPAGKIVMELYTDKTPKTAENFRALCTGEKGVGRSGKPLHFKGSSFHRVIPNFMCQGGDFTKGNGTGGESIYGAKFEDENFERKHTGPGILSMANAGANTNGSQFFICTVKTDWLDGKHVVFGQVVEGLDVVKAIEKIGSSSGKPTKPVVIADCGEISS
Protein: Flap endonuclease (FEN) (EC 3.1.11.-) (5'-3' exonuclease) (Exodeoxyribonuclease) (EC 3.1.11.3) (P06229)
Organism: Escherichia phage T5 (Enterobacteria phage T5)
Function: Catalyzes both the 5'-exonucleolytic and structure-specific endonucleolytic hydrolysis of DNA branched nucleic acid molecules and probably plays a role in viral genome replication. Active on flap (branched duplex DNA containing a free single-stranded 5'-end), 5'overhangs and pseudo-Y structures. The substrates require a free, single-stranded 5' end, with endonucleolytic hydrolysis occurring at the junction of double- and single-stranded DNA. This function may be used for example to trim such branched molecules generated by Okazaki fragments synthesis during replication.
Interaction partners:
Sequence:
MSKSWGKFIEEEEAEMASRRNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTDGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ