wanglab/gogpt-training-data huggingface dataset:
Protein: 14-3-3 protein gamma (Q5F3W6)
Organism: Gallus gallus (Chicken)
Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P68252}.
Interaction partners:
- Cell division cycle 25B.
- 14-3-3 protein epsilon
- Serine/threonine-protein kinase PLK
- 14-3-3 protein zeta
- 14-3-3 protein beta/alpha
- Rhodanese domain-containing protein.
- PH domain-containing protein.
- Forkhead box O3
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELGAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
Protein: Dynamin-related protein DNM1 (EC 3.6.5.5) (P54861)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Microtubule-associated force-producing protein that participates mitochondrial fission. Fission of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. Functions antagonistically with FZO1.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:10559943, ECO:0000269|PubMed:11038182, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:23530241}; Peripheral membrane protein {ECO:0000269|PubMed:10559943, ECO:0000269|PubMed:11038182, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:23530241}; Cytoplasmic side {ECO:0000269|PubMed:10559943, ECO:0000269|PubMed:11038182, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:23530241}. Note=Cytoplasm, localizes to the cytoplasmic outer membrane of mitochondria.
Interaction partners:
- Autophagy-related protein 11
- Mitochondrial fission 1 protein
- Mitofusin FZO1
- Mitochondrial division protein 1
- CCR4-associated factor 4
- Mitochondrial distribution and morphology protein 34
- Mitochondrial distribution and morphology protein 12
- Mitochondrial distribution and morphology protein 10
- Nuclear migration protein NUM1
- Maintenance of mitochondrial morphology protein 1
Sequence:
MASLEDLIPTVNKLQDVMYDSGIDTLDLPILAVVGSQSSGKSSILETLVGRDFLPRGTGIVTRRPLVLQLNNISPNSPLIEEDDNSVNPHDEVTKISGFEAGTKPLEYRGKERNHADEWGEFLHIPGKRFYDFDDIKREIENETARIAGKDKGISKIPINLKVFSPHVLNLTLVDLPGITKVPIGEQPPDIEKQIKNLILDYIATPNCLILAVSPANVDLVNSESLKLAREVDPQGKRTIGVITKLDLMDSGTNALDILSGKMYPLKLGFVGVVNRSQQDIQLNKTVEESLDKEEDYFRKHPVYRTISTKCGTRYLAKLLNQTLLSHIRDKLPDIKTKLNTLISQTEQELARYGGVGATTNESRASLVLQLMNKFSTNFISSIDGTSSDINTKELCGGARIYYIYNNVFGNSLKSIDPTSNLSVLDVRTAIRNSTGPRPTLFVPELAFDLLVKPQIKLLLEPSQRCVELVYEELMKICHKCGSAELARYPKLKSMLIEVISELLRERLQPTRSYVESLIDIHRAYINTNHPNFLSATEAMDDIMKTRRKRNQELLKSKLSQQENGQTNGINGTSSISSNIDQDSAKNSDYDDDGIDAESKQTKDKFLNYFFGKDKKGQPVFDASDKKRSIAGDGNIEDFRNLQISDFSLGDIDDLENAEPPLTEREELECELIKRLIVSYFDIIREMIEDQVPKAVMCLLVNYCKDSVQNRLVTKLYKETLFEELLVEDQTLAQDRELCVKSLGVYKKAATLISNIL
Protein: Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2 (EC 1.2.1.79) (O33340)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable short-chain type dehydrogenase/reductase
- Probable glutamine synthetase GlnA4
- Putative glutamine amidotransferase Rv2859c
- Formylglycine-generating enzyme
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL4
- ATP synthase epsilon chain
Sequence:
MSTTQLINPATEEVLASVDHTDANAVDDAVQRARAAQRRWARLAPAQRAAGLRAFAAAVQAHLDELAALEVANSGHPIVSAEWEAGHVRDVLAFYAASPERLSGRQIPVAGGVDVTFNEPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPAELTPLTTMRLGELAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFTGSTEVGKRVMAGAAAQVKRVTLELGGKSANIVFHDCDLERAATTAPAGVFDNAGQDCCARSRILVQRSVYDRFMELLEPAVHSIVVGDPGSRATEMGPLVSRAHRDKVAGYVPDDAPVAFRGTAPAGRGFWFPPTVLTPKRGDRTVTDEIFGPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVARAVESGNLSVNSHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVFIAVGEEM
Protein: Syntaphilin (Q80U23)
Organism: Mus musculus (Mouse)
Function: Inhibits SNARE complex formation by absorbing free syntaxin-1.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Synapse, synaptosome.
Interaction partners:
- Mitochondrial Rho GTPase 1
- Trafficking kinesin-binding protein 1
- Trafficking protein, kinesin binding 2
- Kinesin heavy chain isoform 5A
Sequence:
MAMSLQGSRRASAGSRRRTSPPVSVRDAYGTSSLSSSSNSGSCKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGVAKEEGTGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSNTSAEDGADSGYVAADDTLSRTDALEASSLLSSGVDCGLEEASLHSSFNLGPRFPASNTYEKLLCGMEAGVQVSCMQERAIQTDFVQYQPDLNTILEKVGQAQVCGSVLKDRHSELDPHPSGPRDPDSAVVVTVGDELEAPEPITCGPATHRPAVNSNPGLPVSVVCPVEEEEEEAAAATTTEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLGQPSSSTAGGSQL
Protein: Cathepsin B-like protease 3 (EC 3.4.22.-) (Cathepsin B3) (AtCathB3) (Q94K85)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp-Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase-1 substrate YVAD-AMC. Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB1 and CATHB2 in basal defense and distinct forms of plant programmed cell death (PCD). Participates in the establishment of basal resistance against the bacterial pathogen Pseudomonase syringae pv. tomato DC3000. Required for full levels of PCD during resistance (R) gene-mediated hypersensitive response (HR). Involved in the regulation of senescence, a developmental form of PCD in plants. May be involved in the degradation of seed storage proteins during seed germination.
Subcellular location: Vacuole {ECO:0000269|PubMed:15539469}.
Interaction partners:
- Vacuolar-processing enzyme beta-isozyme
- Vacuolar-processing enzyme delta-isozyme
- Vacuolar-processing enzyme alpha-isozyme
- Vacuolar-processing enzyme gamma-isozyme
- UPF0235 protein At5g63440
- Eukaryotic aspartyl protease family protein
- Eukaryotic aspartyl protease family protein
- Proteasome subunit beta type-6
- Eukaryotic aspartyl protease family protein
- Thiamine thiazole synthase, chloroplastic
Sequence:
MAVYNTKLCLASVFLLLGLLLAFDLKGIEAESLTKQKLDSKILQDEIVKKVNENPNAGWKAAINDRFSNATVAEFKRLLGVKPTPKKHFLGVPIVSHDPSLKLPKAFDARTAWPQCTSIGNILDQGHCGSCWAFGAVESLSDRFCIQFGMNISLSVNDLLACCGFRCGDGCDGGYPIAAWQYFSYSGVVTEECDPYFDNTGCSHPGCEPAYPTPKCSRKCVSDNKLWSESKHYSVSTYTVKSNPQDIMAEVYKNGPVEVSFTVYEDFAHYKSGVYKHITGSNIGGHAVKLIGWGTSSEGEDYWLMANQWNRGWGDDGYFMIRRGTNECGIEDEPVAGLPSSKNVFRVDTGSNDLPVASV
Protein: Pelophylaxin-4 (Q2WCN5)
Organism: Pelophylax fukienensis (Fukien gold-striped pond frog) (Rana fukienensis)
Function: Antimicrobial peptide.
Subcellular location: Secreted {ECO:0000255, ECO:0000269|PubMed:16139927}.
Interaction partners:
Sequence:
MLTLKKSMLLIFFLGTINFSLCEQERNADEEERRDEPEERDVEVQKRILPFLAGLFSKILGK
Protein: Endoglin (Q6B0K7)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MCRRSSPLLPLLLALLGRPDPAPAEHCDLQPVTAEPPITLFYTTSTVLRGCVSNSSTLASHEVHVLSIQWSKTPVPMLNVSITPRDDDCTRPAALILQCTQCLASITLPCQNLLIHTDASLRPKVQGKELPKDAKGHLLEWVQRTYGGITSYSELKDPQRIHLQLGENSNSPQNCIPQKDFDATPHLEAEVLFREVKGCTSSSAQSAGAAHIVQLLHKPSLPITEVKLTLNCPRQQQNNQILLLQGPANLTWLLMLNNCSLQFLASGTYKILHFPMDPRKGELLPDTEQGLIAKAFEKNYSIIASYSVIPISPHITLNIHEREVPKKLPVGPTSSAPSPDDVSSSLLFTLSPWKCTDDTMEIVIARSNLEPIKDVVNITLRDISCQAEKNATHFMLHTLLSHCGTSLENHGHANNEFVLSLSKGSVLRSVRVAFQCPIPRELFLRLFPSAAFKAPQTELEVNKEVFVQASMHLEDYPADLQLKECYLMAPGMEPLLLVQGNKAQSSSVAMLEEPPSNRARKVWRFRFTYTVPEGRHVPFSATLKCKAGLQNNTIFEKVLEVKVKDVWRLPNNQGLGLSAVLGITFGAFLIGALLTAGLWYIYSHTRPISKLQPVSTTAPASESSSTNHSIGSTQSTPCSTSSMA
Protein: Zinc finger protein BRUTUS-like At1g74770 (F4HVS0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000250|UniProtKB:Q8LPQ5}.
Interaction partners:
- Amino acid transporter AVT6B
- Uncharacterized protein At2g30760
- 2-oxoglutarate
- Putative F-box protein PP2-B6
- Putative U-box domain-containing protein 50
- Disease resistance protein
- Jacalin-related lectin 12
- thiohydroximate-O-sulfate sulfate/sulfur-lyase
- Scopoletin 8-hydroxylase
- Transcription factor ORG3
Sequence:
MGGGNLHSLPPENASVSASYAVTVGNTKLSDAPVLFFVYCHKAFRAQLVELRRFATDAAEADSFSGDLAVELSRKFEFLKLVYKYHSAAEDEVIFLALDKRVKNIVSNYSLEHAGTDDLFTSIFHWLHVLEEEIGSRSDVLREVILCIGTIQSSICQHMLKEERQVFPLLIEKFSFREQASLVWQFICSVPVMVLEDFLPWMISHLSHEEKIEVENCIKDVAPNEDSLQQVISSWLLDDSQSSCGTPTEIMKGVQYVNVSKSLKKSPESHPSSGCFQRFWEWSKKSLSIPNVGRSPIHGLRLFQNAIEKDLRDIQEGLCQAKFQTLILDLDVLMARLNFLADVLVSYSNAFKKFFHPVLEEMTARRSSTAKQFNIDDCLENFQRLLYKSADDKTKTDNFLLQLQEELESLIIQVTKQFAIQRTEVFPIISKNCNHEMQKQLLYTSIHVLPLGLLKCVILWFSAHLSEEESQSILHFLSLEDSSPKKSFPRLLLQWLRFGYSGKTSVERFWKQLDVMFKVRCSCQKEHTEEASGSFSNQTQLQLCKVSKDVYPRKKDKSSTCFMSMDLAVGDMYETPYSSRMNQQMTFSGKLKPPLHLPDFFGEKNMDDPMIMDVKPIDLLFFFHKAMKMDLDYLVCGSTRLAADFRFLAEFQQRFHMIKFLYQIHSDAEDEIAFPALEAKGQLKNISHSFSIDHELETKHFDKVSFILNEMSELNMLVSTINTTAADHDRKMKYERLCLSLREICKSMHKLLSEHIQHEETELWGLFRNCFSIEEQEKIIGCMLGRISGEILQDMIPWLMESLTSDEQLAAMSLWRQATRKTMFVEWLTEWYNGHVLQEEAGEANNDPFGDSDPLEIVWKYLFEASADGEKGSMRSSLLKLPKTNFTGIMNQPPPNYKVEVGKKEEKDLERSESKKICRGSNQEGDKEQTDKMSQKVSQFGPSKKYEQLLTMSEEELVVVIKKISCDSSLDPQKKDYIKQNLLMSRWNISQRTYNLEPSSLSSNMETVHGQHPSYRDPHSLIFGCNHYKRNCKLLAPCCDKLFTCIRCHDEEADHSVDRKQITKMMCMKCLLIQPIGANCSNTSCKSSMGKYFCKICKLYDDERKIYHCPYCNLCRVGKGLGIDYFHCMKCNACMSRTLVEHVCREKCLEDNCPICHEYIFTSSSPVKALPCGHLMHSTCFQEYTCSHYTCPVCSKSLGDMQVYFKMLDALLAEEKMPDEYSNKTQVILCNDCGRKGNAPYHWLYHKCTTCGSYNSRLL
Protein: Origin recognition complex subunit 4 C-terminal domain-containing protein (Q388Q9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKGVFCESGGGECCSFTRSFLSTVQHQLAVQCCRVLAQLTASTGKSFLEVARRGRSPQRHGVTTRDAAEDPSGRRDELGMHLAVYRSVRSAVAASCALGHRSCHMLWGPRGCGAHRLLRLVAQDCMEGNNTFVLYLDGDVLNSDEDALRSIGQQMLTFLRSSNSKSLRSADTSFSKGTFDFGSLFGFSKLMALDKISEGAVQTDAECPSRTKQGSCVTKDLKVSGHEKDGKVGRKRPRLAVPDELLDDGSASEDDDAFHVTSTTAYAMGGASSALAALQRALLLMRTHGTNLIVCIRRVERFGVWCDQLLYVLSGLMHESDGQGGGMSLVMTSSTPDIRQLEKRLSSRLTCEARCIPLLPWSVSCVARACLVEVKERLELKVNTVKARNTKRGRLKKVRSVTDSGASGCTTSHSFTGWRFDAVSAGVAQDQSPEGEVNGYLTPPEVMLLEAAMLEMSGYVLTELSAVARSPQQSVSDVHFAQRIMVLSGQLRSVGATAGRVMTAVSAVFGEVCSGEIPLLSSASCGKLLSWFERTSPKLKVAQNIRSAVFSVAPEAVKSLWRGEFTNANRKSAGSVKPLRNYALLVGDMLSECKLVELGYCTREMFLLLTYVYLRHEAGVVRTVVDLLEDVASSMGTHAAAALDRAAFTAAVGLLNRWRIVRVGGRDGSTAVSLRGSPARLREFLQEVLHRSEYCNETLGLDTKEVARLRSLV
Protein: Nuclear envelope integral membrane protein 1 (F7EXG8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004575}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004575}; Nucleoplasmic side {ECO:0000256|ARBA:ARBA00004575}.
Interaction partners:
Sequence:
METRSPGGLAHSDFLLAGIDVNVVMLQESQVDMNSSQQFCYKNVLIPKWHDIWTRIQVRVNSSKLVRVTQVDSEERLKELEQFSVWNSLSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVTRRFDPKLFLVFLLGLTLFFCGDLLSRSQIFYYSTGMSVGIVASLLIVIFMISKLMPKRSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWHYLLSYILTVGFMSFAVCYKYGPLENERSINLLTWTLQLLGLGFMYSGIQIPHVAFALIVIALCTKNLEYPIYWLYSTYRRMCKASEKPVPPRLLTEEEYRIQGEVETQKALQELREFCNSPECSAWKTISRIQSPKRFADFVEGSFHLTPNEVSVHEQEYGLGSILAQDEELSSEEEGSEDLPLTQNSFLT
Protein: UDP-glucose 6-dehydrogenase 1 (UDP-Glc dehydrogenase 1) (UDP-GlcDH 1) (UDPGDH 1) (EC 1.1.1.22) (At-UGD1) (Q9FZE1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.
Interaction partners:
- UDP-D-apiose/UDP-D-xylose synthase 1
- UDP-D-apiose/UDP-D-xylose synthase 2
- Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1
- UDP-sugar pyrophosphorylase
- Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2
- Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3
- UDP-glucuronic acid decarboxylase 1
- UDP-glucuronic acid decarboxylase 3
- UTP--glucose-1-phosphate uridylyltransferase 2
- UTP--glucose-1-phosphate uridylyltransferase 1
Sequence:
MVKICCIGAGYVGGPTMAVMALKCPEIEVVVVDISEPRINAWNSDRLPIYEPGLEDVVKQCRGKNLFFSTDVEKHVFESDIVFVSVNTPTKTQGLGAGKAADLTYWESAARMIADVSKSSKIVVEKSTVPVRTAEAIEKILTHNSKGIEFQILSNPEFLAEGTAIKDLYNPDRVLIGGRDTAAGQKAIKALRDVYAHWVPVEQIICTNLWSAELSKLAANAFLAQRISSVNAMSALCEATGADVTQVAHAVGTDTRIGPKFLNASVGFGGSCFQKDILNLIYICECNGLPEAANYWKQVVKVNDYQKIRFANRVVSSMFNTVSGKKIAILGFAFKKDTGDTRETPAIDVCNRLVADKAKLSIYDPQVLEEQIRRDLSMARFDWDHPVPLQQIKAEGISEQVNVVSDAYEATKDAHGLCVLTEWDEFKSLDFKKIFDNMQKPAFVFDGRNVVDAVKLREIGFIVYSIGKPLDSWLKDMPAVA
Protein: P-loop containing nucleoside triphosphate hydrolases superfamily protein (F4J3Q8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein GET4
- Protein translocase subunit SECA1, chloroplastic
- Proton pump-interactor 1
- Protein FORGETTER 1
- acid phosphatase
- At1g77230
- Tetratricopeptide repeat
- Ubiquitin receptor RAD23d
- Probable ubiquitin receptor RAD23a
- Ubiquitin receptor RAD23
Sequence:
MATLSSYLLSSPPLCKSRFSATSLVSGIDFISFSPRTTLSSSSTVLPAILSLSVKHNRRRNSLQGSNSKVFLFLNLKQDWISLASLDFDFDFWVSVKSVASPTETISEFDEMVSGTKRKYYMLGGKGGVGKTSCAASLAVRFANNGHPTLVVSTDPAHSLSDSFAQDLTGGMLVPVEGPEAPLFALEINPEKAREEFRSASQMNGGTGVKDFMDGMGLGMLVEQLGELKLGELLDTPPPGLDEAIAISKEFCYSIIVFDTAPTGHTLRLLSLPDFLDASIGKILKLRQKITSATSAIKSVFGKEEKGPDAADKLEKLRERMVKVRELFRDTESTEFVIVTIPTVMAVSESSRLSASLKKESVPVKRLIVNQLLPPSSSDCKFCSIKRKDQMRALDMIREDSELSALTLMEAPLVDMEIRGVPALRFLGDIIWK
Protein: Nucleolar GTP-binding protein 1 (Novel nucleolar protein 1) (Q9V411)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs. Acts as TP53 repressor, preventing TP53 stabilization and cell cycle arrest.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:24255106}. Note=Found in the nucleolus during interphase. {ECO:0000269|PubMed:24255106}.
Interaction partners:
- Guanine nucleotide-binding protein-like 3 homolog
- Probable ribosome biogenesis protein RLP24
- Nucleolar GTP-binding protein 2
- Pescadillo homolog
- Ribosome biogenesis protein NSA2 homolog
- Ribosome assembly factor mrt4
- RRM domain-containing protein
- Ribosome biogenesis protein NOP53
- Probable ATP-dependent RNA helicase pitchoune
- Ribosome biogenesis protein BOP1 homolog
Sequence:
MSLYNFKKIMVVPPAKDFIDIMLSKTQRKTPTVVHKGYKISRIRAFYTRKVKYTQQNFHDRLSQIIQDFPKLDDVHPFYADLMNVLYDKDHYKLALGQLNTARHLVDNVAKDYVRLLKYGDSLYRCKQLKKAALGRMATIMKRQASNLTYLEQVRQHLSRLPTIDPYSRTIIICGFPNVGKSSFINKITRADVEVQPYAFTTKSLYVGHTDYKYLRWQVIDTPGILDHPLEERNVIEMQAITALAHLRACVLYFMDISEQCGHSLEEQVKLFESIKPLFTNKPLILAINKIDILTPEDLPEERRAIITKLQEDKNIPVMLMSTVQETGVMEVKTEACERLLSYRVDQKMRTKKVDNILNRLHVAMPAPRDDKLRAPCIPEKASARLLQNADKAERKRKLEKEIEEEMGDDYTLDLKKNYSEIPEEERYDIIPEFWQGHNIADYIDADIFDKLEELEREEGLREESGVYKVPDMTMDETLKEIREIAKQIRGKRFELRDEKRLSSRKNKPVIPRNKQPKVRDRSVQKLVSTMEGLGVDMSGSENANFTKSVVDLRRGQVAVGSKKVPMQPLLDKESSAVVRKTGQPLKRAPSRDTLGIKNLAIRKKAQIMAKRDIAKKVTSRGLKGEADRFIGTKMPKHLFSGKRGNGKTDRR
Protein: Transcription repressor OFP17 (Ovate family protein 17) (AtOFP17) (Q84RF2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription repressor OFP12
- Transcription repressor OFP7
- Transcription repressor OFP11
- Transcription repressor OFP15
- Transcription repressor OFP14
- Transcription repressor OFP18
- Transcription repressor OFP13
- Transcription repressor OFP6
- Transcription repressor OFP3
- Transcription repressor OFP16
Sequence:
MRVKATLINFKSKLSKSCNRFVSLFRFRVKRPVFIRPLRARHGNVKPRHQHHHSKKPICSCLCFLNSSKNHKMSNAKHRSSSFSVNDDDYSKFMQSPLTPATAKKLFTSPITTPYSSRTRKSLNARDTFEDNAVEDACRSFENYLIHLIVEEGKIDDLMDIEELLFCWKNLKSPVFIELVSRFYGELCRDLFSGE
Protein: Di-or tripeptide:H+ symporter (Q5M4H8)
Organism: Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU003755}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU003755}.
Interaction partners:
- Peptidase T
Sequence:
MEDKGKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSVKVTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLAPKAFNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGLMQGVE
Protein: Chaperone protein TorD (P36662)
Organism: Escherichia coli (strain K12)
Function: Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9632735}.
Interaction partners:
- Trimethylamine-N-oxide reductase 1
- Cytochrome c-type protein TorC
- Cytochrome c-type protein TorY
- Trimethylamine-N-oxide reductase 2
- Dimethyl sulfoxide reductase DmsA
- Probable dimethyl sulfoxide reductase chain YnfF
- Putative dimethyl sulfoxide reductase chain YnfE
- Nitrate reductase molybdenum cofactor assembly chaperone NarJ
- Chaperone NapD
- Tat proofreading chaperone DmsD
Sequence:
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLTAAVNELENRIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVARCRQYDSFGFYAALSQLLLVLVECDHQNR
Protein: Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase) (P32321)
Organism: Homo sapiens (Human)
Function: Supplies the nucleotide substrate for thymidylate synthetase.
Interaction partners:
- Thymidylate synthase
- Deoxycytidine kinase
- Thymidylate kinase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
- Thymidine kinase 2, mitochondrial
- dCTP pyrophosphatase 1
- UMP-CMP kinase 2, mitochondrial
- Cytosolic purine 5'-nucleotidase
- 5'
- Cytosolic 5'-nucleotidase 1A
Sequence:
MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGCSDDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ
Protein: HTH-type transcriptional regulator UidR (Gus operon repressor) (Uid operon repressor) (P0ACT6)
Organism: Escherichia coli (strain K12)
Function: Repressor for the uidRABC (gusRABC) operon.
Interaction partners:
- Beta-glucuronidase
- Uxu operon transcriptional regulator
- Maltose regulon regulatory protein MalI
Sequence:
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLLDLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS
Protein: Prophage antitermination protein Q homolog QuuD (Antitermination protein Q homolog from lambdoid prophage DLP12) (Q47274)
Organism: Escherichia coli (strain K12)
Function: Positively regulate expression of some phage genes. Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes (By similarity).
Interaction partners:
- Prophage lysis protein S homolog EssD
- Prophage outer membrane lipoprotein RzoD
- Prophage Rz endopeptidase RzpD
Sequence:
MRDIQMVLERWGAWAANNHEDVTWSSIAAGFKGLITSKVKSRPQCCDDDAMIICGCMARLKKNNSDLHDLLVDYYVVGMTFMSLAGKHCCSDGYIGKRLQKAEGIIEGMLMALDIRLEMDIVVNNSN
Protein: Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Liver regeneration-related protein LRRGT00195) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)] (P20788)
Organism: Rattus norvegicus (Rat)
Function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster. It cycles between 2 conformational states during catalysis to transfer electrons from the quinol bound in the Q(0) site in cytochrome b to cytochrome c1 (By similarity). Incorporation of UQCRFS1 is the penultimate step in complex III assembly (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q5ZLR5}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q5ZLR5}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- Cytochrome b
- Cytochrome c oxidase subunit 5A, mitochondrial
Sequence:
MLSVAARSGPFAPVLSATSRGVAGALRPLLQSAVPATSEPPVLDVKRPFLCRESLSGQAATRPLVATVGLNVPASVRYSHTDIKVPDFSDYRRAEVLDSTKSSKESSEARKGFSYLVTATTTVGVAYAAKNAVSQFVSSMSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDPQHDLERVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPTYEFTSGDVVVVG