wanglab/gogpt-training-data huggingface dataset:
Protein: Serine/threonine-protein kinase CtkA (Ser/Thr-protein kinase CtkA) (EC 2.7.11.1) (Cell-translocating kinase A) (Q9ZKJ5)
Organism: Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Function: Virulence factor acting as a pro-inflammatory protein that induces the secretion of the pro-inflammatory cytokines TNF-alpha (tumor necrosis factor-alpha) and IL-8 (interleukin-8) from human macrophages, as well as enhanced translocation of the transcription factor NF-kappa-B complex in macrophages. Is a kinase capable of autophosphorylating itself at a threonine residue near the N-terminus. Also leads to enhanced phosphorylation of the NF-kappa-B p65 subunit (RELA) at 'Ser-276' in human epithelial cancer cells; its kinase activity is required for this enhanced phosphorylation that up-regulates NF-kappa-B activity, but it does not directly phosphorylate this protein. Thus, the kinase activity of CtkA may play an important role in the induction of host inflammatory responses during H.pylori infection.
Subcellular location: Secreted {ECO:0000269|PubMed:21098302}. Host cytoplasm, host cytosol {ECO:0000269|PubMed:21098302}. Host nucleus {ECO:0000269|PubMed:21098302}. Note=Translocates into cultured human cells. When examining the cellular location of the transiently expressed CtkA after 0, 12, 24, and 48 hours of transfection, the transiently expressed CtkA translocates from cytosol into nucleus in a time-dependent manner.
Interaction partners:
Sequence:
MPTIDFTFCEINPKKGFGGANGNKISLFYNNELYMVKFPPKPSTHKEMSYTNGCFSEYVACHIVNSLGLKVQETLLGTYKNKIVVACKDFTTHQYELVDFLSLKNTMIELEKSGKDTNLNDVLYAIDNQHFIEPKVLKCFFWDMFVADTLLGNFDRHNGNWGFLRASNSKEYQIAPIFDCGSCLYPQADDVVCQKVLSNIDELNARIYNFPQSILKDDNDKKINYYDFLTQTNNKDCLDALLRIYPRIDMNKIHSIIDNTPFMSEIHKEFLHTMLDERKSKIIDVAHTRAIELSLQHKQAHSNPYDNADDLDNSNEYTPTPKRRR
Protein: Myocardin related transcription factor A (F1LV40)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTLLEPEMLMMAVQSVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEALIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLESRASDLLPSATSISPTQVLSQLPMAPDPGETLFLAEQPPLPPPPLLPPSLTSGSIVPTAKPAPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPPKPSGETPGSSAPTPSRSLSTSSSSSSGTPGPGGLARQNSTALAGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTSVLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNGMVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDAFGEMVTSPLTQLTLQASPLQIVKEEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASSPVKRESSFSSCQLSCQPQGAARAFGPGLVVPTTNHGDAQAPAPESPPVVVKQEAGPPEPDLAPASQLLLGSQGTSFLKKVSPPTLVTDSTGTHLILTVTNKSADGPGLPTGSPQQPLSQPGSPAPGPPAQMDLEHPPQPSFATPTSLLKKEPPGYEETVTQQPKQQENGSSSQHMDDLFDILIQSGEISADFKEPPSLPGKEKSPPAEAYGPPLTPQPSPLSELPQAAPPPGSPTLPGRLEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSPMDTSELHFAPEPSSGMGLDLAVGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSMDFLDGHDLQLHWDSCL
Protein: Fbxl18 protein (A4VCH8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSSEEEAAAEAAGDTHLLGFSDEILLHILSHVPSTDLVLSVRRTCRKLAALCLDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLSGSTIEHVARCHSLVKVNLSGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPKSWLNGSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLLRKAEDD
Protein: Sliding-clamp-loader small subunit (Clamp loader gp62 subunit) (Gene product 62) (gp62) (P04527)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Forms the sliding-clamp-loader together with the small subunit. The clamp loader holds the clamp in an open conformation and places it onto the DNA.
Interaction partners:
Sequence:
MSLFKDDIQLNEHQVAWYSKDWTAVQSAADSFKEKAENEFFEIIGAINNKTKCSIAQKDYSKFMVENALSQFPECMPAVYAMNLIGSGLSDEAHFNYLMAAVPRGKRYGKWAKLVEDSTEVLIIKLLAKRYQVNTNDAINYKSILTKNGKLPLVLKELKGLVTDDFLKEVTKNVKEQKQLKKLALEW
Protein: RNA binding motif protein 15 (A0A087WWP4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSASVVGASVGGHRHPPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRDLERERDYPFYERVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRGFGFQIGVRYENKKRENLALTLL
Protein: Dinoflagellate luciferase (EC 1.13.12.18) (O77206)
Organism: Lingulodinium polyedra (Dinoflagellate) (Gonyaulax polyedra)
Function: Emits blue light flashes with a wavelength of 475 nm during the night phase.
Subcellular location: Cytoplasmic vesicle {ECO:0000269|PubMed:15665092}. Note=Localizes in scintillons, specialized organelles formed as outpocketings from the cytoplasm into the acidic vacuole.
Interaction partners:
Sequence:
MAAQLEQFLVNEGQVDQRAVTYMLKGLQLESLSDFASFWTSKDYENGVRDDIISKVAPFNSDLSLPAAKLQVARLRAAWRKAQGKPSAAVPLQSAKPVAGSVVTATKDTGFCEKTGLESGGVAHGGALNAAQVAHLDEDAFKGGLHRPKFDSEGLHKPHTSGGKTYETGFHYLLEAHELGGKNADGGFGGPLCADPFSPEIEQLCQALVREAQDDKTLCFENFTKPCPQLTKKQVELCKGFDYGDKTLKLPCGPLPWPAGLPEPGYVPKTNPLHGRWITVSGGQAAFIKEAIKAGMLGAAESHKIMADTDHHQTGGMYLRINQNGDVCTVDASVAKFARAKRTWKSGHYFYEPLVSGGNLLGVWVLPEEYRKIGFFWEMESGRCFRIERRAFERNGLMIMRQATEVAGKISFVFYVKVSNDPESKPIPLQSRDYTALAGLDNVPDSLGNPYTCEAKDLDYPIKRDTWLDKNQEEMLKQRSIVGTAFAKCCDQGFEAHDNPKGGALTAAHVESLGKENFKNGLHAPNFHDDGLHKPMEAGGKVYSTGFHYLLEAHDLGGKNEDGGYGGPLCKDPYGKEVQSMVENLLVQANVDTTNAFDNFKQPCPQLTKEQVAMCKGFDYGDKTLKLPCGPLPWPAGLPEPGYVPKTNPLHGRWITVSGGQVAFIKEAIKSGMLGAAEAKKIIADTDHHQTGGMYLRINQYGEVCTVDASVAKFARAKRTWKSGHYFYEPLVSGGNLLGVWVLPEEYRKIGFFWEMESGHCFRIERRAFPCGPYMFLRQATEVGGKISYVFYVKVSNDPGSKPIPLQSRDYTALAGQDNAPDNLGKPYKCTARDLDAPTKRDGWLDTNKGAMLDQREKVSKAFAKVCEKGFEAGDNKLGGALNAKHVEKYGDNFKNGMHKPEFHEDGLHKPMEVGGKKFESGFHYLLECHELGGKNASGGYGGPLCEDPYGSEVQAMTEKLLKEADSDRTLCFNNFQDPCPQLTKEQVAMCKGFDYGDKTLKLPCGPLPWPAGLPEPGYVPKTNPLHGRWITVSGGQAAFIKEAIKSGMLGAAEANKIVADTDHHQTGGMYLRINQFGDVCTVDASVAKFARAKRTWKSGHYFYEPLVSGGNLLGVWVLPEEYRKIGFFWEMESGRCFRIERRAFPVGPYTFMRQATEVGGKISFVFYVKVSNDPESDPIPLQSRDYTALAGRDNAPTNLGKPYPTLAKDLDYPKKRDGWLEKNEKEMLRQRNIVSSTFRS
Protein: WD repeat-containing protein 1-A (Actin-interacting protein 1-A) (xAIP1-A) (Q9W7F2)
Organism: Xenopus laevis (African clawed frog)
Function: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Doesn't sever actin filaments alone, but caps the barbed ends of filaments severed by cofilin, which blocks annealing and depolymerization and allows more extensive severing by cofilin.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10212149}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10212149}. Nucleus {ECO:0000269|PubMed:10212149}.
Interaction partners:
Sequence:
MPYELKKVFASLPQMERGVAKILAGDPKGNNFLYTNGKSVIIRNIDNPAIADIYTEHAHQAVVARYAPSGFYIASGDTSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFASVFLWDTGSSVGEITGNIKVINSVDIKQTRPYRLVTGSDDNCCAFLEGPPFKFKFTMSDHSRFVNCVRFSPDGSKLASAGADGQIFLYDGKTGEKVCSLGGSKAHDGGIYAVSWSPDGTQLLSASGDKTTKIWDVAANSAVTTFNLGSDVLDQQLGCLWQKDYLLSVSLSGYINYLDKNNPARPLRVIKGHNKSIQCMTVNNSDGRSTIYTGSHDGHINYWDAETGENDTFTGKGHTNQVSSMDLDGCNQLITCSMDDTLRYTSLISKDYSSSESVKMDVQPKCVAVGSGGYVVTVCIGQIVLLKDKKKVFAIDSLDYEPEAVAIHKGSGTVAVGGADGKVHLYSIQGNSLKDEGKTLPAKGAVTDLAYSHDGAFLAVTDANKVVTVFSVADGYSEKNSYYGHHAKALSVAWSPDNEHFASSGMDMMVYVWTLSDPDTRIKMPDAHRLHHVSSLAWLDEHTLATVSHDACVKQWTVTFK
Protein: Early gene at 23, isoform C (Early gene at 23, isoform D) (Early gene at 23, isoform E) (FI20292p1) (Q7KU30)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- LD11139p
Sequence:
MIISKDLFIFGEQIFATIIPEGGAAALATQQQHQQQHQQQHQQSHQQPHQQSQQQQQQQQPAIINSTTTTATSLVINSTAGAAEQVVEESLKVAAAAAAATTTTTAAAATTLPAKQETVAVAAACVAPRKLAKIQKIPKEPEELKAKKKAKCEAAAAATHYEKMPMNLMIVESVEAVDMGSSDNDNETTEQVPLVSASRRNLAKIVADCRLQIEVEPATSAVAAAAAAAASVASPPATSDATAATSVASSDSSASSSASSTSSSSSSSTSSEFTHTSQTTIPSTDNLTSSNGLANIGKSILVDAKSNSPASLSYHFEKSAAANQQKQHHNINICNSHHPHHHSQNQPQHSLQLTFQNLNVLHNERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDSGSVFLNREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSHPDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRNFREAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFFSQTYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLGCTSLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLATQLFGGYLSSRIPEGLSWIRYTSMIHYAYQNMQILEFREGAAIGCGSPSSYEICKQQSTEFIPYEEILKAQNSTSPLWLNTLILMMFFLVFRCLGYAVLRFLRCPKKT
Protein: Uncharacterized protein (F4K0G5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSHSSSVNLLHYHYLPPDFNHSFRLCLTAPSSSRWSSPDDYCSILAMPTTTLPGSISPFNVPHSVRTKKPNGQQKKEEIEKEVWMLREMLDQEEKTREILEQVQKHQLPSSSSSLTLPASLPPKMKELITELSIVEGEISRLEIQISHLQINLKQEQDETLKQATTSSSRRAWQTSETYKDDNINPYQAPTLPKYPKLPPPSPMVNKGMMKSENNNTKSTTSHHQENATFGTKTLHFINKAIKGDYAIESFRKSNEKVGVVEKENHRSVQHENKVQENMKMKKIRTMKSPSPLREPRYTSPNKPNKDRVAALDASLDIPPKSLSSTILMEDGQNIQKWHPNKLAENIMKCLNFIYVRLLRTTRVMELEKTGPISRSTNFSLSSRSFRVDNATSSLSKSMNLVSYKESRQQDPYGIFDVESSLARDIGPYKNLVIFTSSSMDSKCISSSSSVSLIQKLRVLMNNLETVDLKVLSHQQKLAFWINMFNACVMHGYLQHGVPKTAERLQSLVYNKATMNVGGKNISAHTIEHCILRKSTSSTMTQDRHEEMIIRKLYGVEATDPNITFALSCGTRSSPAVRIYTGEGVTTELEKSKLEYLQASLVVTAAKRIGLPELLLKHATDFVVLTADGGTGEMEQLGSLVKWVCNQLPTSGSLRKSMVDCFKNPNSKASSSSSAVEKIPYDFEFQYLLAI
Protein: Acyl carrier protein (Q57WW9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial
- beta-ketoacyl-[acyl-carrier-protein] synthase I
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Electron transfer protein, putative
- NADH-ubiquinone oxidoreductase, mitochondrial, putative
- Large ribosomal subunit protein bL21m
- Uncharacterized protein
- Reiske iron-sulfur protein, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- 50S ribosomal protein L17, putative
Sequence:
MQRSQLARKFATQVGAYSLLRGRCHAVSTWKVMATQAVTIPMYLPVRFHSEGHAAGEEAGRTGQYLLNKDDVLTRVLEVVKNFEKVDASKVTPQSHFVNDLGLNSLDVVEVVFAIEQEFILDIPDHDAEKIQSITDAVEYISQNPMAK
Protein: Scribble planar cell polarity protein (A0A669KB89)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLKCIPLWRCNRHVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTEDDARTGEKVLTCYLLPQQPPPSLEDAGQQGSLSETWSDAPPSRVSVIQFLEAPIGDEDAEEAAAEKRGLQRRATPHPSELKVMKRSIEGRRSEACPCQPDSGSPLPAEEEKRLSAESGLSEDSRPSASTVSEAEPEGPSAEAQGGSQQEATTAGGEEDAEEDYQEPTVHFAEDALLPGDDREIEEGQPEAPWTLPGGRQRLIRKDTPHYKKHFKISKLPQPEAVVALLQGMQPDGEGPVAPGGWHNGPHAPWAPRAQKEEEEEEEGSPQEEEEEEEEENRAEEEEASTEEEDKEGAVVSAPSVKGVSFDQANNLLIEPARIEEEELTLTILRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERMVEPENAVTITPLRPEDDYSPRERRGGGLRLPLLPPESPGPLRQRHVACLARSERGLGFSIAGGKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIALLLEREAGGPLPPSPLPHSSPPTAAVATTSITTATPGVPGLPSLAPSLLAAALEGPYPVEEIRLPRAGGPLGLSIVGGSDHSSHPFGVQEPGVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVRRDPAPPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGFEASTDAALEVSPGVIANPFAAGIGHRNSLESISSIDRELSPEGPGKEKELPGQTLHWGPEATEAAGRGLQPLKLDYRALAAVPSAGSVQRVPSGAAGGKMAESPCSPSGQQTKPGVIQPLAQAWPRGSPAPRGRGCPHSPPSPPSPDELPANVKQAYRAFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQQKRAQMLREAAEAGAEARLALDGETLGEEEQEDEQPPWASPSPTSRQSPASPPPLGGGAPVRTAKAERRHQERLRVQSPEPPAPERALSPAELRALEAEKRALWRAARMKSLEQDALRAQMVLSRSQEGRGTRGPLERLAEAPSPAPTPSPTPVEDLGPQTSTSPGRLSPDFAEELRSLEPSPSPGPQEEDGEVALVLLGRPSPGAVGPEDVALCSSRRPVRPGRRGLGPVPS
Protein: Chromosomal replication initiator protein DnaA (O66659)
Organism: Aquifex aeolicus (strain VF5)
Function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
Interaction partners:
- Beta sliding clamp
- Replicative DNA helicase
- Type 2 topoisomerase subunit B
- DNA replication protein DnaC
- DNA primase
- Protein RecA
- tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
- Large ribosomal subunit protein bL34
- Type 2 topoisomerase subunit A
- Integration host factor beta subunit
Sequence:
MELNALIKKIESVDSYAREFLKKFEIKQEKGKFLFIAPGEDYREWLETIVNTFLEEEVRKLIEVKEKEEKKKVEIKDFLNPKYTLENFIVGEGNRLAYEVVKEALENLGSLYNPIFIYGSVGTGKTHLLQAAGNEAKKRGYRVIYSSADDFAQAMVEHLKKGTINEFRNMYKSVDLLLLDDVQFLSGKERTQIEFFHIFNTLYLLEKQIILASDRHPQKLDGVSDRLVSRFEGGILVEIELDNKTRFKIIKEKLKEFNLELRKEVIDYLLENTKNVREIEGKIKLIKLKGFEGLERKERKERDKLMQIVEFVANYYAVKVEDILSDKRNKRTSEARKIAMYLCRKVCSASLIEIARAFKRKDHTTVIHAIRSVEEEKKKDRKFKHLVGFLEKQAFDKIC
Protein: At2g22880 (VQ motif-containing protein) (O81005)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- VQ motif-containing protein 8, chloroplastic
- Protein STABILIZED1
- Cell division cycle 5-like protein
- VQ motif-containing protein 22
- VQ motif-containing protein 20
- VQ motif-containing protein 11
- Protein MKS1
- VQ motif-containing protein
- VQ motif-containing protein
- At5g65170
Sequence:
MEATSQPCFSHNSSLHSTRKQPAKPWKKPVTGLPQRMHPKVYRVEPVNFKELVQRLTGAEDVEQEVHQVEAKPVKISDDTTTAKDNPFAFDLSPSSSRFWEAFPLLSPANLSRW
Protein: Ankyrin repeat domain 27 (A0A8I6APD4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MALYDEDLLRNPFYLALQKWRPDLCSKVAQIHGIVLVPCRGSLPSNVQASCQFESYVLVPMEGHFQTLDGKPRESSAYRLGGPWYTPSQVCIPLRY
Protein: Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Q59VF4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Histone H4
- Histone acetyltransferase type B subunit 2
- Tetratricopeptide SHNi-TPR domain-containing protein
- Origin recognition complex subunit 3
- Origin recognition complex subunit 5
- Origin recognition complex subunit 4
- Origin recognition complex subunit 2
- Origin recognition complex subunit 6
- Histone chaperone ASF1
- Histone-binding protein RBBP4-like N-terminal domain-containing protein
Sequence:
MSSAKEQSSVTAALQPEQWTTSSNEALKLFVTNPEAALNFQPTFTYPIFGDAETIYGYKDLDIFLCFDHYTFKPFLNIKYSAKLTDDPEIIDIKKTIDEFLPKSTIFKDEVKWVDSIKEEKDNGYKIPGKLIDSFSENDKEYDIYKIDLKSDNGYELHQRLQILVLLFIEAGSFIDAKDELWNLYVLYEKDNKSTSNNEPSIVGFTTAYNYWKYPGAKKFDSTEQESRIKISQFIILPIYQGQGLGQLFYSHLFDKWLAQDDIIEVVVEDPNESFDDLRDRADLKRLNTSEQFDFKAVTPKVDKEWVEKTRRALKLEKRQFARLLEIILLYKLKHGYPGITKRDVRLFIKKRLYDKNKEGLATLDDNTKKDKLQTAYQALEDDYYRILGDLKLNIKRENDEEETDTVSKKQKV
Protein: Superoxide dismutase [Mn/Fe] (EC 1.15.1.1) (Q9Y8H8)
Organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
Interaction partners:
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL13
- aconitate hydratase
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein uL3
- Protease I
- Succinate--CoA ligase subunit alpha
- Small ribosomal subunit protein uS15
- Pernisine
- Peroxiredoxin
Sequence:
MVSFKRYELPPLPYNYNALEPYIIEEIMKLHHQKHHNTYVKGANAALEKIEKHLKGEIQIDVRAVMRDFSFNYAGHIMHTIFWPNMAPPGKGGGTPGGRVADLIEKQFGGFEKFKALFSAAAKTVEGVGWGVLAFDPLTEELRILQVEKHNVLMTAGLVPILVIDVWEHAYYLQYKNDRGSYVENWWNVVNWDDVEKRLEQALNNAKPLYLLPQ
Protein: 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) (Q9D6Y9)
Organism: Mus musculus (Mouse)
Function: Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule.
Interaction partners:
- Glycogen [starch] synthase, muscle
- Glycogen [starch] synthase, liver
- Glycogen phosphorylase, liver form
- Glycogen phosphorylase, muscle form
- Glycogen debranching enzyme
- Glycogen phosphorylase, brain form
- Glycogenin-1
- Ornithine transcarbamylase, mitochondrial
- Alpha-amylase 1
- Pancreatic alpha-amylase 2a5
Sequence:
MAAPAAPAAGETGPDARLEAALADVPELARLLEIDPYLKPFAADFQRRYKKFSQVLHDIGENEGGIDKFSRGYESFGIHRCSDGGIYCKEWAPGAEGVFLTGEFSGWNPFSHPYKKLEYGKWELYIPPKQNKSPLIPHGSKLKVVITSKSGEILYRISPWAKYVVRENNNVNYDWIHWAPEDPYKFKHSRPKKPRSLRIYESHVGISSHEGKIASYKHFTSNVLPRIKDLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELKELVDTAHSMGIVVLLDVVHSHASKNSEDGLNMFDGTDSCYFHSGPRGTHDLWDSRLFIYSSWEVLRFLLSNIRWWLEEYCFDGFRFDGVTSMLYHHHGMGQGFSGDYNEYFGLQVDEDALIYLMLANHLAHTLYPDSITIAEDVSGMPALCSPTSQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGNIVYTLTNRRYLEKCVAYAESHDQALVGDKTLAFWLMDAEMYTNMSVLAPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFNLTDDDLLRYKFLNNFDRDMNRLEERCGWLSAPQAYVSEKHEANKTITFERAGLLFIFNFHPSKSYTDYRVGTATPGKFKIVLDSDAAEYGGHQRLDHNTNYFAEAFEHNGRPYSLLVYIPSRVALILQNVDLQN
Protein: Holliday junction resolvase MOC1, chloroplastic (EC 3.1.21.10) (Protein MONOKARYOTIC CHLOROPLAST 1) (CreMOC1) (A8ITB0)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products (By similarity). Mediates chloroplast nucleoid segregation during chloroplast division.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:28495749}.
Interaction partners:
Sequence:
MRVLGFLSSHAGTGTAAAHTRWRWLAPLGIQAIRPASASAGGNAVSSATPQAPPCPIHANVGVGRASALGPGPSGFMAPSAGIVTAIRDGPNSNSRCSTVRTHATRSKSTGPSRATSSGPATAAPPRRRRRTSNDTQDGGLTSEQTPTNTAVAAVAATAAAAAGASASAAAPALPVALNPTWRTPPTAEAARRITQAASASAAYSGSSAAAAAAAVAAGPSSAASVARGGSAAAARSAAASALAANANTSSGAASAAAIAATASTAPGKLLLGGDLSRALAAAGSTTAPPLPLPSRAGLSAPKHTASAAAAAAAAASVLPASTPAAASQTPPTTVTSCGTGSGAPATPRAARSPTAAVSVSSADAAAAAAAAAAPASAAATAAAAVLPTRHIVAAVDPDLNGALALIYWDEDPNDPTTATASGPAAATTDAAAAAAAAAAAATGPAARLATLAAAAPPGSGAAAAADEAAAAALLWLPTPPRPPADASRWRVCVWDMPVSAAERQKRTASGQVARRRLLHVAGARAVLSAALAAALPPPGEARPVALYGYVEVPPILPGDGNIAAYTSLWSTGSWLGLLTGMGFTVGSTPVRRWKTDLGLYGAKGKDASLALARALFPGQQPILRHKKNHGRADALLIAAWALGACLPRGLGASLRRNGITLDQLLQQQPGTTVGLVWGPPRPPAPTDAYGNLLTPEQDMWDEIEAAETKVERKAQARSSTARRRKTAGTQEEPEAQAEEEQAEAGTGVVAAAAGAAAPKRRRAKKAAVESGSEAAVAEVAAGPQEEGSEGEVAGQGGRACRSKSRSKSSGKSSSKAEAGGAGSGRRRAASVGSSSVGSSSVGSSSGGGGGGGGGVKAPGASRRRGGAKAGSDGGVSGSESE
Protein: Heterogeneous nuclear ribonucleoprotein (HnRNP) (Q7KA80)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKREMNDEGEGPQDQKRNRRNEETVRILIPSSIAGAVIGKGGQHIQKMRTQYKATVSVDDSQGPERTIQISADIESTLEIITEMLKYFEERDEDFDVRLLIHQSLAGCVIGKGGQKIKEIRDRIGCRFLKVFSNVAPQSTDRVVQTVGKQSQVIEAVREVITLTRDTPIKGAIHNYDPMNFDRVYADEYGGYGTGSGSTRPSQRGNNRNGGGAGGVAGGAAGGNGGGFNAGGARGNAGGRGGADRFGGAAGGAVAGAGMGQRDNPFINPWANGGGGDVDGFGNNPGGAGGFAGNSFGGGAGGPFGGGSFGNNGFGGGPSDFGGNSGNFGQAQGTNSLPSLGSFSQNQGGTSSLPSLGSFGQNPGGPGGLGNGLSGGANGGVGTLGGANGAGGFNAVGGANGGPNGSPNAATNVPQGHDPNNSTQVTIPKELAGAIIGKGGGRIRRIRNESSAYITIDEPLPNSNDRIITISGTPKQIQMAQYLLQQSVHENGRRNI
Protein: UTP--glucose-1-phosphate uridylyltransferase 1 (EC 2.7.7.9) (UDP-glucose pyrophosphorylase 1) (AtUGP1) (UDPGP 1) (UGPase 1) (P57751)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Converts glucose 1-phosphate to UDP-glucose, which is the major glycosyl donor for polysaccharides. Acts redundantly with UGP2 and is essential for the synthesis of sucrose, starch and cell wall, and callose deposition. Involved in the regulation of the programmed cell death (PCD) induced by the fungal toxin fumonisin B1 (FB1).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Probable phosphoglucomutase, cytoplasmic 2
- Probable phosphoglucomutase, cytoplasmic 1
- Phosphoglucomutase, chloroplastic
- ADP-glucose phosphorylase
- Alpha-glucan phosphorylase 1
- Alpha-glucan phosphorylase 2, cytosolic
- Sucrose-phosphate synthase 1
- Sucrose-phosphate synthase 4
- UDP-sugar pyrophosphorylase
- Probable sucrose-phosphate synthase 3
Sequence:
MAATATEKLPQLKSAVDGLTEMSENEKSGFINLVSRYLSGEAQHIEWSKIQTPTDEIVVPYDKMANVSEDASETKYLLDKLVVLKLNGGLGTTMGCTGPKSVIEVRDGLTFLDLIVIQIENLNNKYNCKVPLVLMNSFNTHDDTQKIVEKYTKSNVDIHTFNQSKYPRVVADEFVPWPSKGKTDKDGWYPPGHGDVFPSLMNSGKLDAFLSQGKEYVFIANSDNLGAIVDLKILKHLIQNKNEYCMEVTPKTLADVKGGTLISYEGKVQLLEIAQVPDEHVNEFKSIEKFKIFNTNNLWVNLKAIKKLVEADALKMEIIPNPKEVDGVKVLQLETAAGAAIRFFDNAIGVNVPRSRFLPVKATSDLLLVQSDLYTLVDGFVTRNKARTNPTNPAIELGPEFKKVASFLSRFKSIPSIVELDSLKVSGDVWFGSGVVLKGKVTVKANAGTKLEIPDNAVLENKDINGPEDL
Protein: Ubiquitin thioesterase Otu1 (EC 3.4.19.12) (Yod1 deubiquitinase) (Q9VRJ9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Interaction partners:
- Phospholipase A2 activator protein, isoform A
- Ubiquitin fusion degradation protein 1 homolog
- Transitional endoplasmic reticulum ATPase TER94
- Nuclear protein localization protein 4 homolog
- GH01724p
- Uncharacterized protein
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin conjugation factor E4 B
- Ubiquitin conjugation factor E4 A
- Ubiquitin-ribosomal protein eL40 fusion protein
Sequence:
MTGSFSVKLKSKKGQFIVNDLNEHTTLGELKTKIVQATDIEATQLHVLVGYPPKPLDLSQQQEQRALKAVGINSGETLIVEEKAAPAPAAPVPGGTTVEDDEALARRLQAEEEAQLLQETAGGPVAQAADYQLPVAPTESGPNGDFNGILLKKVVPADNSCLFTSIRFVLNGKVDNEGSEMMRHIIAQEVAADPQSYNDAVLGKSNAEYCAWIQKADSWGGAIEVSILSNYYGIEIDVVDIQNAIINRFGEDKNFGLRVFLLFDGIHYDPLYMETSPSAAPATIFPVEELGVYQQAEQLANEAQSSRQYTNVDKFTLRCMQCDVRLVGQVQAQEHAKQTGHKNFGEI
Protein: RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (Q6GMF9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- RanBP-type and C3HC4-type zinc finger-containing protein 1
- Uncharacterized protein.
- Tumor necrosis factor receptor superfamily, member 1a.
- Receptor
- TNF receptor-associated factor
- TNF receptor-associated factor
- Tnf receptor-associated factor 5.
- RING-type E3 ubiquitin transferase
- X-linked inhibitor of apoptosis.
- Receptor-interacting serine-threonine kinase 2.
Sequence:
MAALDASRNVTEAEDAARLLSDAINSRDKDEATKYLNQLLDLKLPVSVKINPDAYSQDNIRLRVGVADAESEHHIPITVMVPVYMTISELKEKINGDYGFHPSLQRWVIGKRLAQDKETLYFYGIRNHDDSAFLFIRSAQSVNLRREQERREKEERQIDVIMETIERPLQRPPERITRGNTRPALPPKPKFLDGWACPQCTYLNKPTRPGCEMCSTARPDNYQVPDLYQPDESETRRLQQEELASLQYEQSLLQEEERNFLERQRNYEELLQTDAHSLVGNTDQLECAICFGTIMPGEGAVLRECLHSFCRDCLKGTVVNCLDAEVCCPYGDNAYACNCKLQDREIKSLLTQDEYQKFLELRLNIAESRSENSYHCKTPDCAGWCIFEDDVNEFKCDICNETNCLLCKAIHKGMNCKEYQDDLRVRAQNDEAARQTTEMLDQLLKNGEAMNCPKCQVIVQKKDGCDWICCLMCKTEICWVTKQARWGPLGAGDTSGGCKCRVNGVLCHPQCQNCH