wanglab/gogpt-training-data huggingface dataset:
Protein: Collagen alpha-1(IV) chain (Collagen type IV alpha 1) (P08120)
Organism: Drosophila melanogaster (Fruit fly)
Function: Collagen type IV is specific for basement membranes.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane.
Interaction partners:
- Viking, isoform A
- Integrin beta-PS
- Pericardin
- BM-40
- Integrin beta-nu
- Laminin subunit gamma-1
- Laminin subunit beta-1
- Terribly reduced optic lobes, isoform AT
- Laminin subunit alpha
- Nidogen
Sequence:
MLPFWKRLLYAAVIAGALVGADAQFWKTAGTAGSIQDSVKHYNRNEPKFPIDDSYDIVDSAGVARGDLPPKNCTAGYAGCVPKCIAEKGNRGLPGPLGPTGLKGEMGFPGMEGPSGDKGQKGDPGPYGQRGDKGERGSPGLHGQAGVPGVQGPAGNPGAPGINGKDGCDGQDGIPGLEGLSGMPGPRGYAGQLGSKGEKGEPAKENGDYAKGEKGEPGWRGTAGLAGPQGFPGEKGERGDSGPYGAKGPRGEHGLKGEKGASCYGPMKPGAPGIKGEKGEPASSFPVKPTHTVMGPRGDMGQKGEPGLVGRKGEPGPEGDTGLDGQKGEKGLPGGPGDRGRQGNFGPPGSTGQKGDRGEPGLNGLPGNPGQKGEPGRAGATGKPGLLGPPGPPGGGRGTPGPPGPKGPRGYVGAPGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPGNEGPPGKKGEKGTAGLNGPKGSIGPIGHPGPPGPEGQKGDAGLPGYGIQGSKGDAGIPGYPGLKGSKGERGFKGNAGAPGDSKLGRPGTPGAAGAPGQKGDAGRPGTPGQKGDMGIKGDVGGKCSSCRAGPKGDKGTSGLPGIPGKDGARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPALCDLSLIEPLKGDKGYPGAPGAKGVQGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPGIPGQSIKGEPGFHGRDGAKGDKGSFGRSGEKGEPGSCALDEIKMPAKGNKGEPGQTGMPGPPGEDGSPGERGYTGLKGNTGPQGPPGVEGPRGLNGPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPGISRPGPMGPPGLNGLQGEKGDRGPTGPIGFPGADGSVGYPGDRGDAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPGVPGIDGVRGRDGAKGEPGSPGLVGMPGNKGDRGAPGNDGPKGFAGVTGAPGKRGPAGIPGVSGAKGDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPGEKGNQGFPGLDGPPGLPGDASEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPGLAVHGRAGPPGEKGDQGRSGIDGRDGINGEKGEQGLQGVWGQPGEKGSVGAPGIPGAPGMDGLPGAAGAPGAVGYPGDRGDKGEPGLSGLPGLKGETGPVGLQGFTGAPGPKGERGIRGQPGLPATVPDIRGDKGSQGERGYTGEKGEQGERGLTGPAGVAGAKGDRGLQGPPGASGLNGIPGAKGDIGPRGEIGYPGVTIKGEKGLPGRPGRNGRQGLIGAPGLIGERGLPGLAGEPGLVGLPGPIGPAGSKGERGLAGSPGQPGQDGFPGAPGLKGDTGPQGFKGERGLNGFEGQKGDKGDRGLQGPSGLPGLVGQKGDTGYPGLNGNDGPVGAPGERGFTGPKGRDGRDGTPGLPGQKGEPGMLPPPGPKGEPGQPGRNGPKGEPGRPGERGLIGIQGERGEKGERGLIGETGNVGRPGPKGDRGEPGERGYEGAIGLIGQKGEPGAPAPAALDYLTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSPGSCVPRFSTLPVLSCGQNNVCNYASRNDKTFWLTTNAAIPMMPVENIEIRQYISRCVVCEAPANVIAVHSQTIEVPDCPNGWEGLWIGYSFLMHTAVGNGGGGQALQSPGSCLEDFRATPFIECNGAKGTCHFYETMTSFWMYNLESSQPFERPQQQTIKAGERQSHVSRCQVCMKNSS
Protein: Transcriptional regulatory protein RCO1 (Q04779)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalytic component of the RPD3C(S) histone deacetylase complex responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, DNA damage response, osmotic stress response and developmental events.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Transcriptional regulatory protein UME1
- Transcriptional regulatory protein SIN3
- Histone deacetylase RPD3
- Chromatin modification-related protein EAF3
- Transcriptional regulatory protein SDS3
- Transcriptional regulatory protein PHO23
- Transcriptional regulatory protein RXT2
- Histone-lysine N-methyltransferase, H3 lysine-36 specific
- Histone H3
- Transcriptional regulatory protein DEP1
Sequence:
MDTSKKDTTRSPSHSNSSSPSSSSLSSSSSKEKKRPKRLSSQNVNYDLKRRKIITSEGIERSFKNEHSNLAVEDNIPEEEPKELLEKDSKGNIIKLNEPSTISEDSKVSVTGLPLNKGPSEKIKRESLWNYRKNLGGQSNNSEMTLVPSKRFTQVPKNFQDLNRNDLKTFLTENMTEESNIRSTIGWNGDIINRTRDREPESDRDNKKLSNIRTKIILSTNATYDSKSKLFGQNSIKSTSNASEKIFRDKNNSTIDFENEDFCSACNQSGSFLCCDTCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFINNSMATLKKIESNFIKQNNNVKIFAKLLFNIDSHNPKQFQLPNYIKETFPAVKTGSRGQYSDENDKIPLTDRQLFNTSYGQSITKLDSYNPDTHIDSNSGKFLICYKCNQTRLGSWSHPENSRLIMTCDYCQTPWHLDCVPRASFKNLGSKWKCPLHSPTKVYKKIHHCQEDNSVNYKVWKKQRLINKKNQLYYEPLQKIGYQNNGNIQIIPTTSHTDYDFNQDFKITQIDENSIKYDFFDKIYKSKMVQKRKLFQFQESLIDKLVSNGSQNGNSEDNMVKDIASLIYFQVSNNDKSSNNKSASKSNNLRKLWDLKELTNVVVPNELDSIQFNDFSSDEIKHLLYLKKIIESKPKEELLKFLNIENPENQSE
Protein: folate gamma-glutamyl hydrolase (EC 3.4.19.9) (Q6NY42)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Interaction partners:
- Folylpolyglutamate synthase
- Zgc:153031.
- Dihydrofolate reductase.
- folate gamma-glutamyl hydrolase
- Folate gamma-glutamyl hydrolase.
- Sphingomyelin phosphodiesterase acid-like 3B.
- Ubiquitin-conjugating enzyme E2 variant 3
Sequence:
MIHIFLLCLFTVANAVSIYNFGPLIKTNERPIIGVLAQDVFDPKPDRNSYIAASYVKFLESAGARVVPVMINKSEDEYSRLFKSINGVLFPGGGVSLESSGYSKAAGIFYRLALEANSNGDYFPVWGTCLGFELLTLLTSGELLLSHTNTSGIALPLDFTEDVKGSRLFKEFPEELMKSLATEPLTENSHQWSITTENFTANKKLKKFYRVLSTNTDGYNKFVSTMEAYDFPIYATQWHPEKNAFEWTRPYIPHTPSAIKTTFYMANFFVNEARKNLHSFASTEEEEKALIYNYKPEYTGIQSAFEQTYFFN
Protein: Tensin 1 (H0Y4U1)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}.
Interaction partners:
Sequence:
MEQLVKERKGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR
Protein: SAP domain-containing protein (F4KAQ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transcription factor bHLH147
- Probable histone-arginine methyltransferase 1.4
- Probable protein arginine N-methyltransferase 1.2
Sequence:
MEASSSQPSDSSDQTASKFLSDLPSRGFLSSTVVSSNPGSLRVYICEHDTSPPVIGSLRIISFRIKGQLIKTNQQNILIRSLLLKKQKGESSSKDSKGTAEDGPKKRAANRALDDRSSAKRAANASRQEGSSSRTGERDFQSLTVEKLRAMLKEKGLPTKGRKDELIARLKSAN
Protein: Set1 complex component swd2 (Set1C component swd2) (COMPASS component swd2) (Complex proteins associated with set1 protein swd2) (O60137)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: The Set1 complex specifically methylates 'Lys-4' of histone H3.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Set1 complex component swd1
- Set1 complex component swd3
- Histone-lysine N-methyltransferase, H3 lysine-4 specific
- RNA polymerase II subunit A C-terminal domain phosphatase ssu72
- Set1 complex component spp1
- Set1 complex component ash2
- Set1 complex component shg1
- Set1 complex component sdc1
- Uncharacterized RING finger protein P8B7.15c
- mRNA 3'-end-processing protein yth1
Sequence:
MTTVSITFDLLSSMQPRKWLKNQNFVGEITSLSFDDSGELCLASCTDDTLQLYNCISGKFVKSLASKKYGAHLGRFTHHSNSLIHASTKEDNTVRYLDVVTNRYLRYFPGHKQTVTSIDVSPADETFLSASLDNTIRLWDLRSPNCQGLLNVSSPVVAAFDATGLIFASVSERKYKISLYNIKSFDARPFQDIPLTFLPPHVRIANVEFSTDGKYLLLTTGNDFHYVIDAYSGSELLRVPSKVSTKTQDGNLTYYASACMSPDSKFLFTSYDNEHLCMYQLPELKQTVNSDHIVNSFTEMGLASTTPTSNSHSTENPLAIIPSSTSKNLLPETPSIVRFNPRFSQLVTAHSGVIFWT
Protein: KIN17-like protein (Q9ZVU5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes the copper deficiency response by direct interaction with SPL7. Acts with SPL7 in a common pathway to promote copper-responsive genes and alleviate oxidative stress during copper-limiting periods. May promote SPL7 function when copper is limiting. Participates in the control of general plant growth and development, and in the response to counteract the negative effects of UV radiation.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:24335506}. Note=Nuclear localization with a speckled distribution pattern. {ECO:0000269|PubMed:24335506}.
Interaction partners:
- At2g32600/T26B15.16
- Squamosa promoter-binding-like protein 7
- Nuclear protein-like
- DNAJ protein JJJ1 homolog
- Transmembrane emp24 domain-containing protein p24beta2
- Calmodulin-lysine N-methyltransferase
- At5g26610
- Splicing factor SF3a60 homolog
- At1g31870
- Pre-mRNA-splicing factor 38
Sequence:
MGKNDFLTPKAIANRIKAKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQMQVFGQNPTRVVDGYSEEFEQTFLDLMRRSHRFSRIAATVVYNEYINDRHHVHMNSTEWATLTEFIKHLGKTGKCKVEETPKGWFITYIDRDSETLFKERLKNKRVKSDLAEEEKQEREIQRQIERAAEKLNGGGGEGETSGNDEVVDDGDDERKKDEDLRLKSGVKVGFALGGGVKQVATGKERGESSKLLFGDEENDKVERGEKRKRSGDSGRSEKERRSALDELMKEEEKKKERMNRKDYWLFEGIIVKVMSKALAEKGYYKQKGVVKKVIDNYVGEIKMLDSKHVLRVDQKELETVLPQIGGMVKIVNGAYRGSNARLLGVDTEKFCAKVQIEKGVYDGRVIKSIEYEDICKLA
Protein: Phosphatidylethanolamine-binding protein homolog F40A3.3 (O16264)
Organism: Caenorhabditis elegans
Interaction partners:
- Coiled-coil and C2 domain-containing protein 1-like
- Large ribosomal subunit protein mL40
- Small ribosomal subunit protein uS2m
- Methionine--tRNA ligase, mitochondrial
- Large ribosomal subunit protein uL16m
- Large ribosomal subunit protein uL4m
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein bL19m
- SRR1-like domain-containing protein
- Ribosomal protein L13
Sequence:
MVVLVTRSLLPALFFASRAPFAAATTSARFQRGLATMAAEAFTKHEVIPDVLASNPPSKVVSVKFNSGVEANLGNVLTPTQVKDTPEVKWDAEPGALYTLIKTDPDAPSRKEPTYREWHHWLVVNIPGNDIAKGDTLSEYIGAGPPPKTGLHRYVYLIYKQSGRIEDAEHGRLTNTSGDKRGGWKAADFVAKHKLGAPVFGNLFQAEYDDYVPILNKQLGA
Protein: Chromatin structure-remodeling complex subunit rsc9 (RSC complex subunit rsc9) (Remodel the structure of chromatin complex subunit 9) (Q9P7W8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000255|PROSITE-ProRule:PRU00858, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Chromatin structure-remodeling complex subunit rsc7
- Chromatin structure-remodeling complex subunit rsc1
- Chromatin structure-remodeling complex subunit rsc4
- Chromatin structure-remodeling complex subunit sfh1
- SWI/SNF and RSC complexes subunit ssr3
- SWI/SNF and RSC complexes subunit arp9
- SWI/SNF and RSC complexes subunit ssr1
- Chromatin structure-remodeling complex subunit rsc58
- SWI/SNF and RSC complexes subunit ssr2
- Chromatin structure-remodeling complex subunit snf21
Sequence:
MSQVIQGAVEEPVYSNKSLTNENDSFLSLIESFSQERGVPIDINPKIGRKPILLYELYKKVIKRGGYDAVSATEDGWTNIAEEFNQSDPARSAGILQNVYFKYLISWEIHDHWHLLLPPPSTLELSENRQNVLERVKVFNSCSPPKPTNPITIIDNDKTHSFKKFYKSLVKEDEENGIEKKINEAMNSSASQPLPNSTNFASTTFPSVPFHPLPVDSGLQKYIDRNSNLTPPALGAGVPGPPLLVRVALALKSQQDKEVDWAIGHLIKISFERHQEFKLERLPSLAECLVYSLGFQVTKAKQVSDLTDISLCMDRAIGIALVLRNSVLSVENAKHVAQTKLVISVLEASIRCAKTFNNLEFLHYCLDISEMISSYLHVEDEKNVFYLALCEFLNSSDYSILIATLRTLARLALNDRNNRLLQDLKSNVIANIIALVETDNEEIVAAALDFLYQYTTYRTNTSNLLASQEAWMLVDQLIRLMMYQAQERFMTVTIENSESNPAVKHEATSSISLPMEELQQLVAMREPERSVKWMRCCFEPSSDDYVLQTDIWQLYCSDMERAQGPNVMGISPADFIKVSSHAFYNARAMTVSTPQLPVEYVINGIKRRKFPTSVNGMRYQPCRWCLDSGKECGELLLGTPLLHSHLQEMHIFPQILETGKCRWSDCKYEIQRLTPASELSHYQLLSHIVTHLHDDSLETLVEGRKLSPSREFRIPLLLTAVDDQGDATGIALTATLVLRNLVRSKQGKMLFSAIESRVLEVSSLNPAVAPYVSEMLLGQI
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A0A8I5ZQ07)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHGQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQVLGGGKPTHEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPLEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPQLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPVLESSLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPSKVKPEESRDIPRPSRPASYKKAIDEDLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGKNEQYNMGMVGTHGLETSHADTFGGSISREGTLMIRETAEEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDTGAEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDDESSAAALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
Protein: Inhibitor of growth protein (E7ET07)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU361213}.
Interaction partners:
Sequence:
MDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK
Protein: Internal virion protein gp20 (Ejection protein gp20) (E protein gp20) (Q01076)
Organism: Salmonella phage P22 (Bacteriophage P22)
Function: Inner capsid protein that plays a role in viral DNA ejection into the host cell. Ejected from the capsid after penetration the host outer membrane and has been released. Assembles into a structure that extends the extracellular trans-envelope channel formed by the internal virion protein gp7 and probably gp16. This channel allows the delivery of the viral genome into the cell cytoplasm.
Subcellular location: Virion {ECO:0000269|PubMed:328927}.
Interaction partners:
Sequence:
MATWQQGINSGGFLAGIGAQNENAPKARDINATLGLIRENNDLARSGANNVALTGLRGLAGVADIYNQEQQQKALNAFNQVHANAWATGDPSGLFKFAQENPAFVAQAQQAFSGLNEQQRNDMGDLAMKANVALSQGPEAYSKFITDNKDRLNRVGANPDWMIQTGVQNPEQLSHMLTTMSLGALGPEKAFAVQDKMVGREIDRGRLAETIRSNKAGEGLQARGQNITMRGQDMSAATARRGQDLATQRANARTISGSEGNRVVQLADGRTVSVGGKLHGAGANAFYEGIDDNGNMVRVPASAIAAPPTSAASAQNYAMKKDIDAIANADASALDFMTGMTGGAGNPAIGADVRSRLTGKEQRQLYNSAQRIQGRMQNQGVAAARDMGASGINTIAEAKMYFQGMPQVDYSSPEAMQQSIREIQEYTNNYNQQYNVNVGNGGLKSPRQQPDTQQSAGGSYTSKSGIKFTVE
Protein: Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) (A0A8I6AIH6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion {ECO:0000256|HAMAP-Rule:MF_03221}.
Interaction partners:
Sequence:
MASAVAIAAQAGKLLRERSLRPRLLAVRSQAGHLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVASTAKEAQEAAKRLNAKEIVLKAQILAGGRGKGVFDSGLKGGVHLTKDPKVVGQLAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVLVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQIKKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKESQVYQAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACQELELKVPLVVRLEVVLGAQAASLKTQTLMESHCLCPEVQVRTQGKPKATTHHRVP
Protein: Secreted effector protein sopD2 (Salmonella outer protein D 2) (Q8ZQC8)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to the formation of Salmonella-induced filaments (Sifs) in infected epithelial cells and to replication in macrophages.
Subcellular location: Secreted {ECO:0000269|PubMed:12535274}. Host cell membrane {ECO:0000269|PubMed:12535274}. Note=Secreted via type III secretion system 2 (SPI-2 T3SS), and delivered into the host cell. Membrane-associated. Localizes to the Salmonella-containing vacuole (SCV) in infected cells and to late endocytic compartments in transfected cells.
Interaction partners:
- Secreted effector protein SseJ
- Secreted effector protein PipB2
- Secreted effector protein SifA
- Secretion system effector
- Secretion system effector
- E3 ubiquitin-protein ligase SopA
- Deubiquitinase SseL
- Guanine nucleotide exchange factor sopE2
- Secreted effector kinase SteC
- Secreted effector protein PipB
Sequence:
MPVTLSFGNRHNYEINHSRLARLMSPDKEEALYMGVWDRFKDCFRTHKKQEVLEVLYTLIHGCERENQAELNVDITGMEKIHAFTQLKEYANPSQQDRFVMRFDMNQTQVLFEIDGKVIDKCNLHRLLNVSENCIFKVMEEDEEELFLKICIKYGEKISRYPELLEGFANKLKDAVNEDDDVKDEVYKLMRSGEDRKMECVEWNGTLTEEEKNKLRCLQMGSFNITTQFFKIGYWELEGEVLFDMVHPTLSYLLQAYKPSLSSDLIETNTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISEKSSCRNMLI
Protein: Down and out, isoform C (M9PBB6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASSTSSARGNNKAATTNTTAATAPVSTASSAAVSGSGATSAAATASAPPAVTLSELIGQQLKHLNADELLHKDELQLLLLITPVQRQKLSRNLEDGDLEASTSAAPLSRPENGEEDDDLIGAVGGLGISSPTTTKEPVLDFRPHVLKWFQHLRHQTGHFKSEEESRRLREAGNDSYRKERHPLKASDLFTEAIFLAPARNTLAAALAHANRSLVLFDCGLYAESYDDCLCALDLGYPEEYLPLIKLRQAACALKLRNFALCEEHLHELLHIELNQVFEARTHELWHQCEVLKVERFEMAVQTGDDLDINDSKAFEIAWLDNSSSLHTTRAVAKNALIFESEAVAMVPSGNCRVCDYCGITQFIPFPCIYCSNRLVVYCSRQCRFKHAAIHAVECFGHQIELFESFGEVFGMPRLLQLAFRMLITGLPELLGHCRKKPTLSKLWSAINGGLQERQDIAYSAVLRLERLKEERPTDTVIALALAAHILSIYLSKCTTFFDQLEKSLPTASRMSSAEWELLCAALLMRHIGQLRHRSLTACRSFVLPADPHVFSPLNEFQLWAAPMRLQEGHLHLLAGEVAVVSYSVYPDTLNLCRHSCSSTICAKFSGRTVTALALLDLPAGSGIYNCFAGGNFQQLPREERTKQLLESGIRCHCNACQLTHSDDQFHKFHRYRCDNPNCMEIFTPNALPHAPSLRWWLSEEYTQPEFNGADLIMCPHCGEYQKLEWFWAFTTSLIDCELIEERCKLYAAIERAENQLMDLHECKVALARLLLEQCLMVHRAHVSLLVAHLFRFLIYRFIEFIQIIHII
Protein: Protein PSK SIMULATOR 1 (AtPSI1) (Q9XID5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes seedling growth probably via the regulation of phytosulfokine (PSK) signaling; PSK are peptide phytohormones acting as growth factors. Together with PSI2 and PSI3, required during vegetative growth and reproduction. May also have a function in carbohydrate metabolism.
Subcellular location: Nucleus {ECO:0000269|PubMed:25062973}.
Interaction partners:
Sequence:
MGGLCSRSSSVNNAPGGTFAHVNGHHLNNNASDLNSHSGESGLKDDPSPVTENVDDNKHTSESFSFPIVSSGSHPQNIEDGIPRLSRVLSQKSRSTKSRQAAVAKVSEVSSLLGRAGTMGLGKAVDVLDTLGSSMTNLNLSGGFSSATTVKGNKISILSFEVANTIVKGANLMHSLSKDSITHLKEVVLPSEGVQNLISKDMDELLRIAAADKREELRIFSGEVVRFGNRCKDPQYHNLDRFFDRLGSEFTPQKHLKQEAETIMHQMMSFVHFTADLYHELHALDRFEQDYQRKIQEEENPSTAQRGVGDTLAILRTELKSQKKHVRNLKKKSLWSRILEEVMEKLVDVVHFLHLEIHEAFGGADPDKPANDPPINHKKLGSAGLALHYANIITQIDTLVSRSSTMPASTRDALYQGLPPSIKSALRSRIQSFQVKEELTVPQIKAEMEKTLQWLVPVATNTTKAHHGFGWVGEWASSGSEANQRPAGQTILRIDTLHHADKEKTEAYILDLVVWLHHLVTQVRATTGYGLRSPVKSPIRSPNQKTIQLSSGSHNPSMGLPLLTTEDQEMLRDVSKRRKTPGISKSQEFETVAKARLCKHHRLSKSSSHSPMMGEMMKNKKDTFSTRRPSSVPIIDFDIDRMKALDVIDRVDTIRSL
Protein: Protein UmuD (EC 3.4.21.-) (DNA polymerase V) (Pol V) [Cleaved into: Protein UmuD'] (P0AG11)
Organism: Escherichia coli (strain K12)
Function: Involved in UV protection and mutation. Poorly processive, error-prone DNA polymerase involved in translesion repair. Essential for induced (or SOS) mutagenesis. Able to replicate DNA across DNA lesions (thymine photodimers and abasic sites, called translesion synthesis) in the presence of activated RecA; efficiency is maximal in the presence of the beta sliding-clamp and clamp-loading complex of DNA polymerase III plus single-stranded binding protein (SSB). RecA and to a lesser extent the beta clamp-complex may target Pol V to replication complexes stalled at DNA template lesions.
Interaction partners:
- Protein UmuC
- Protein RecA
- DNA polymerase IV
- Beta sliding clamp
- DNA polymerase III subunit alpha
- DNA repair protein RecN
- DNA polymerase III subunit epsilon
- DNA damage-inducible protein I
- DNA polymerase II
- Regulatory protein RecX
Sequence:
MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLLIQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLRPTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR
Protein: Transcription factor che-1 (Abnormal chemotaxis protein 1) (Q966L8)
Organism: Caenorhabditis elegans
Function: Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Probable histone-binding protein lin-53
- Histone-lysine N-methyltransferase mes-2
- Polycomb protein mes-6
- Receptor-type guanylate cyclase gcy-5
- Homeobox protein ceh-36
- LIM/homeobox protein lim-6
- COG-1A
- LIM/homeobox protein ttx-3
- Homeobox protein ttx-1
- Nuclear hormone receptor family member odr-7
Sequence:
MSYHYQMNNNNTDFFDSANYIPQMQMHHGYQDFYASDSTSSMPSSGTTQQALQQTENGIIQGQNGSDHGVAFHFRAYGGWRQHDWNSTSSWSIGNQLEMENGTLTMSHGATNDGNIRNNQQMMTSNHITTDSFRQIPPSGLCYMDPTPSLRLPKKEPLPVQRPMARSTPKPFRCQTCGKAFSQAANLTAHKRIHTGEKPFMCPVCNRPFSQSSSLVTHRRTHTGERPYPCAQCEKAFTDSSTLTKHLRTHTGHKPYVCSICMMKFTQSGNLHRHMKTHK
Protein: Suppressor of cytokine signaling SOCS36E (Suppressor of cytokine signaling at 36E, isoform A) (Suppressor of cytokine signaling at 36E, isoform C) (Q9VJA1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGHHLSKFSARANSQEKRNPTASSSPREAAALVETISLDEEELQVEEILTEATVSAATSPAEVRQIIIKIQLAKMENGNPVAAGQVESFAEVVEQEEEQQRQCADGATDDDAAALSADSLNANGQIVNVTLEGGYGEVGVVTNRTAGSSPEAAKTERQPVNNNGLAGSVGAAISTLQLHDNHGGNANCPLEADDDDDLDESLLRRRRSNSNSRSNIHHHHHHHQQQQQQQHEAEVVEYCEVLESLPVSNMLSAGTQHSSKPVSRSNNSNSCCRSRSSKALSMGAATSSASGSASTSVSTSTSSKRRCCKCKCRDAIRGLRDMLPSSSSSVSNKKDAAAVVAMVPRKSRTADRRSTPPTLGTSSGGSQRRMQSQRIRNSVAVPDASHHHHQLIIRITSPGFVVESPNGGRVTVVTEPAPQSPQTPPRPRPLATVAPAGGAGHAGIGAARNMTVHSQIDFMHCLVPDLEKITNSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKFSFDCHDPCVFTAPTVTGLLEHYKDPACVMFFEPCLTIPLHRRQTFSLQQLSRATIVSNTSYDGINQMELPGRLKSYLKEYHYKQKLRVKPIDQNTPMPYYGNV
Protein: Signal peptide, CUB and EGF-like domain-containing protein 1 (Q8IWY4)
Organism: Homo sapiens (Human)
Function: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Subcellular location: Secreted {ECO:0000269|PubMed:12270931, ECO:0000269|PubMed:16753137}. Cell membrane {ECO:0000269|PubMed:16753137}; Peripheral membrane protein {ECO:0000269|PubMed:16753137}.
Interaction partners:
- Signal peptide, CUB and EGF-like domain-containing protein 3
Sequence:
MGAAAVRWHLCVLLALGTRGRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLGPSCSDAPTTPIKQKARFKIRDAKCHLRPHSQARAKETARQPLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRPAKALEGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECGGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK