wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein, isoform F (M9PBR6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Oxysterol-binding protein
- Steroidogenic acute regulatory protein-like
- RE14391p
- Oxysterol-binding protein
Sequence:
MGVKVKETTPQQIEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNSLWETCILRQSTGANDIDESELNQEYLKEGSVFVHNTDVDGKPLLVFRVKMHSKSKNLDELIRIVVYWVERTQREQHLTQLTIFFDMSGTSLASMDLEFVKRIVETFKQFYPNSLNYILVYELGWVLNAAFKVIKAVLPPKAVEILKMISKKDINQYINKDNCLAIWGGEDNYEFSFVPEAKKVISKPVAANAGDDDQFADKKVTFVDSAPMVLKETNINKMHTPSEGMLHINPKDFVNFNSKNAEATMTIKSIATSAVTYKIQTTSPEKFRVRPRCGIIQPNQEATINIWLKSEHKLSDDSKDKFLVMAMVAPGGECGGADVTELWRSKSPTSADVEQHRLVCRFDENKSKAQLDCASKSSKASVDCSKKSGAGVDPATAMERQLAFTQNLQYVTLALLFLLFAGFGFLMYQQLGQHAATCPKATAYSCAKRKXYLLSPCNLTRQELDIAARDSHNNNEDDCDCPELENCACAVDLMNLGLDCADTMDQYDGECLEALIQAHLQLCLSCQGTGDWQLGGVAAGGHLLGFIAFARKMVRVVLSLSLLCGILFVSFYLGSNYGGNSTTTTITTSLATVDSGRGNRQPCYYS
Protein: Patellin-4 (Q94C59)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Carrier protein that may be involved in membrane-trafficking events associated with cell plate formation during cytokinesis. Binds to some hydrophobic molecules such as phosphoinositides and promotes their transfer between the different cellular sites (By similarity).
Subcellular location: Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly membrane-associated. Also cytoplasmic (By similarity). {ECO:0000250}.
Interaction partners:
- Sec14p-like phosphatidylinositol transfer family protein
- AT1G14820 protein
- Sec14p-like phosphatidylinositol transfer family protein
- SEC14 cytosolic factor family protein / phosphoglyceride transfer family protein
- Sec14p-like phosphatidylinositol transfer family protein
- AT3g10210/F14P13_19
- Uncharacterized protein At4g36500
- Transmembrane protein
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH14
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH13
Sequence:
MTAEVKVEEKQVESEVVIAPAVVPEETTVKAVVEETKVEEDESKPEGVEKSASFKEESDFFADLKESEKKALSDLKSKLEEAIVDNTLLKTKKKESSPMKEKKEEVVKPEAEVEKKKEEAAEEKVEEEKKSEAVVTEEAPKAETVEAVVTEEIIPKEEVTTVVEKVEEETKEEEKKTEDVVTEEVKAETIEVEDEDESVDKDIELWGVPLLPSKGAESTDVILLKFLRARDFKVNEAFEMLKKTLKWRKQNKIDSILGEEFGEDLATAAYMNGVDRESHPVCYNVHSEELYQTIGSEKNREKFLRWRFQLMEKGIQKLNLKPGGVTSLLQIHDLKNAPGVSRTEIWVGIKKVIETLQDNYPEFVSRNIFINVPFWFYAMRAVLSPFLTQRTKSKFVVARPAKVRETLLKYIPADELPVQYGGFKTVDDTEFSNETVSEVVVKPGSSETIEIPAPETEGTLVWDIAVLGWEVNYKEEFVPTEEGAYTVIVQKVKKMGANEGPIRNSFKNSQAGKIVLTVDNVSGKKKKVLYRYRTKTESSS
Protein: CSC1-like protein At4g35870 (Q9SZT4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as an osmosensitive calcium-permeable cation channel.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- DnaJ homolog subfamily C GRV2
- PX domain-containing protein EREL1
- Ureide permease 4
- ADP-ribosylation factor C1
- Vacuolar-sorting receptor 1
- Vacuolar protein sorting-associated protein 29
- Vacuolar sorting protein 3
- Hyperosmolality-gated Ca2+ permeable channel 3.1
- Vacuolar protein sorting-associated protein 51 homolog
Sequence:
MNRNFSPAAMPPISSMTIDNSFSPPPSSGDLPEIPDAWYGNIQYLLNISVIGLLCCVSIFLFVKLRSDHRRMPGPSALFSKLLAVWKATCREIARHCGADAAQFLLIEGGSFVLLFSIAVLAVSVMLPLNLYAGTALLSDELSKTMITHIQKGSALLWLHFVFVVIVVVISHFGIAAIEARLKFTRFRDGNGNISDPNANSTAVFTIMVQGLPKNLGSDRVEFEDCFRLKYPGKVYKFIVPMDLCALDDLATELVRVRDEITWLVAKMDSRLLPDEYENVGDNGLVFCVCSLWVRVKVLWSQITERFGFTDDEKLRKLQELRADLESQLAAYKEGRAQGAGVAFVMFKDVYTANKAVQDFRNERSRRTGKFFSVTELRLQRNQWKVDRAPLATDIYWNHLGLTKVALIVRRVIVNTILLLILVFFSSPLALISALVSAGRIFNAEALDSAQYWLTWVQTSGWIGSLIFQFLPNVFIFVSMYIVIPSALSYLSKFERHLTVSGEQRAALLKMVCFFLVNLIILKALVESSLESALLKMSRCYLDGEDCKRIEEYMSPSFLSRSCVSALAFLITSTFLGISFDLLAPIPWIKKKIQKFRKNDMLQLVPEQNEEYALENQEPSSNLETPLLPENMFESPRFGDIEPMSQDLSEYPISRTSPIPKQKFDFAQYYAFNLTIFALTMIYSSFAPLVVPVGAVYFGYRYIVDKYNFLYVYRVRGFPAGNEGKLMDTVLCIMRFCVDLYLVSMLLFFSVKGDSTKLQAIFTLGVLVMYKLLPSDTDRYHPALLRSIQTVDSIIDGPVDYEAYSHPNFDWDTYNNR
Protein: Eng protein (Q3KR75)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MDRSMLPLVITLLLVIYSFVPTSLAERVGCDLQRVDSTRGEVTYTTSQVSEGCVAQVANAAHEVHVLFLNLSRRKSEVELTLQASKQNGTETREVFLVFISNENVLVKLQAPEIPLHLVYNSSLEVFKGPKVNSTPLPSFTSKTQILDWAATKGTITSIAALDDPKSIVLRLGQDPKAPPFCFPEAQKDMGVTLEWQPRTQTPVQGCHLEGVTGHKEAYVLRIRSGSEAGPRTVTVTVKLSCTSGDAVLILQGPPYVSWLIDTNHNMQIWTTGEYSIKIFPENNIKGFELPDTPQGLIGEARKLNASIVTFVEIPLTSDVSLTVSSCGGGLQTSPAPVVTTPPKDTCSPELLMSLIQPKCGNDVMTLALNKKLVQTLQCTITGLAFWDSSCQAKDQDGHLVLSSTYSSCGMKVTDHVISNEVIINLPSGLPPLRKKVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQGFVQVSMSPLTSEVTVQLDSCHLDLGPEGDMVELIQSRAAKGSCVSLLSPSPEGDPRFSFLLRVYMVPTPAAGTLSCNLALHPSTLSQEVYKTVSMRLNIVSPDLSGKGLVLPSVLGITFGAFLIGALLTAALWYIYSHTREYPKPLHPLPTVSAQGRSTPPQGTPWEASEEVGSPGWGPDLHPCPHLSGAPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
Protein: PHD finger protein ING2 (Protein INHIBITOR OF GROWTH 2) (Protein AtING2) (B3H615)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Subcellular location: Nucleus {ECO:0000269|PubMed:19154204}.
Interaction partners:
- Histone acetyltransferase subunit NuA4-domain protein
- Enhancer of polycomb-like protein
- Histone acetyltransferase of the MYST family 1
- Enhancer of polycomb-like protein
- SWR1-complex protein 4
- Homeobox protein HAT3.1
- Transcription factor GTE3, chloroplastic
- Cysteine proteinase inhibitor 4
- Histone H3-like 2
- Histone H3-like 1
Sequence:
MAIARTGVYVDDYLEYASTFPAELQRLLNTVRELDERSQSLINQTRQQTKYCLGLASQSSKKGNGNHYNNGGLDEEETIEKMRKEIESSQENALSLCTEKVLLARQAYDLIDSHVKRLDEDLNNFAEDLKQEGKIPPDEPSVLPPLPIVPKAEKRKSFYGTPQPKKIDYRDRDWDRDRDFELMPPPGSNRKDLMPIEEQPIDPNEPTYCVCHQVSFGDMIACDNENCQGGEWFHYTCVGLTPETRFKGKWYCPTCRLLPQSH
Protein: Neuropathy target esterase sws (Swiss cheese) (DSWS) (EC 3.1.1.5) (Q9U969)
Organism: Drosophila melanogaster (Fruit fly)
Function: Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain. Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15772346, ECO:0000269|PubMed:18945896}; Single-pass type I membrane protein {ECO:0000269|PubMed:15772346, ECO:0000269|PubMed:18945896}. Note=Sws tethers Pka-C3 to the membrane.
Interaction partners:
- BcDNA.GH02384
- Uncharacterized protein, isoform A
- phospholipase A2
- LD22655p
- Lysophosphatidylcholine acyltransferase
- Phospholipase A2
- palmitoyl-protein hydrolase
- Lysophospholipid acyltransferase 5
- Phospholipase A2
- Phospholipase A2
Sequence:
MDVLEMLRASASGSYNTIFSDAWCQYVSKQITATVYMYFALVMMSLLFIAWFLYFKRMARLRLRDEIARSISTVTNSSGDMRGLRFRKRDKMLFYGRRMLRKMKNVSGQMYSSGKGYKRRAVMRFARRILQLRRDNMPLEMRTVEPPAEYLEETIEGSDRVPPDALYMLQSIRIFGHFEKPVFLRLCKHTQLLELMAGDYLFKITDPDDSVYIVQSGMINVYISNADGSTLSLKTVRKGESVTSLLSFIDVLSGNPSYYKTVTAKAIEKSVVIRLPMQAFEEVFQDNPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRYKSVSTMSGPINSQTSQSSRQAPNGPPMVISQMNLMQSAVSGTGSSGVSVTVTRPPSSPSRHSREEHTLSDPNPNPDGSFHGTTNLFTEVHGDAPNADLFHQQQQQHSVGNLSTRRSSITLMAPDGSHSCLQTPGVTTSIDMRLVQSSAVDSLRKELGLSEEDSHIIEPFVELRELEPNVTLITEGNADDVCVWFVMTGTLAVYQSNQDATRAKQDKSDMLIHFVHPGEIVGGLAMLTGEASAYTIRSRSITRIAFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITHPGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIVVTKLISFLSHRFLGSMQTRSGSGAPGAPVEANPVTHKYSTVALVPITDEVPMTPFTYELYHSLCAIGPVLRLTSDVVRKQLGSNIFEAANEYRLTSWLAQQEDRNIITLYQCDSSLSAWTQRCMRQADVILIVGLGDRSHLVGKFEREIDRLAMRTQKELVLLYPEASNAKPANTLSWLNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPVDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPKDGHLLLDGGYVNNLPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFESMAKAGRLGRFNQWFNKEPPKRVNHASLNEYTFIDLAQIVCRLPETYAVNTAELFSEDEDCDGYISEPTTLNTDRRRIQVSRAGNSLSFSETEMDSDVELDLKLERKTDKSTQSSPPSNSRSDMRGKEEARHMSNWHWGVKHKDETGSGATEATKTQTGQEQELQQEQQDQGATAEQLVDKDKEENKENRSSPNNETKN
Protein: Uncharacterized protein Rv0479c (P9WKV7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Hydrolase Rv0480c
- Uncharacterized protein Rv0481c
- Probable conserved membrane protein
- Exported repetitive protein
- Membrane protein Rv1476
- PPE family protein PPE2
- Possible conserved transmembrane alanine and glycine rich protein
- Possible lipoprotein LprC
- Lipoprotein LpqB
- Probable conserved exported protein
Sequence:
MTNPQGPPNDPSPWARPGDQGPLARPPASSEASTGRLRPGEPAGHIQEPVSPPTQPEQQPQTEHLAASHAHTRRSGRQAAHQAWDPTGLLAAQEEEPAAVKTKRRARRDPLTVFLVLIIVFSLVLAGLIGGELYARHVANSKVAQAVACVVKDQATASFGVAPLLLWQVATRHFTNISVETAGNQIRDAKGMQIKLTIQNVRLKNTPNSRGTIGALDATITWSSEGIKESVQNAIPILGAFVTSSVVTHPADGTVELKGLLNNITAKPIVAGKGLELQIINFNTLGFSLPKETVQSTLNEFTSSLTKNYPLGIHADSVQVTSTGVVSRFSTRDAAIPTGIQNPCFSHI
Protein: F-box domain-containing protein (Q389F8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWDLVCSYLNVQDVKKLSGTCRFLWELLRPRDNVWRVQLDYFREDMKNLYGEGRLLCTELFVPPSCSAYEQMKLELQLYIMDTHREWQLKDREKTDGPYGMFSCPLTLAHDPSINEEGWQDEDVTPFSQLRIIRAVRLFPSGLSTSQSLRHNGGSGSIFTPSEYMMLCENINHGDFTGSRLGVQDHVDEEGGLLQFALMETLRRAKYRKPPRCSTGEVRTSSHLVLRHFGGLLLSICRYEAEDILDSLLHKRGLVDDFVTYCNYRERSTTNRPCFPFPCQSRYYIAPELCRRGRVGLIITDSVRLLVVVGKELVTRDDARWGSDFAAAAAAGRTVYGGGMNPQQPRLV
Protein: Proteasome 20S subunit beta 10 (G3V8J3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Cationic trypsin-3
- Bile salt-activated lipase
- Chymotrypsin-like elastase family member 2A
- Carboxypeptidase A1
- Chymotrypsin like elastase 3B
- Carboxypeptidase B
- Chymotrypsinogen B
- Colipase
- Pancreatic triacylglycerol lipase
- Inactive pancreatic lipase-related protein 1
Sequence:
MLLLSLTLSLVLLGSSWGCGVPAITPALSYNQRIVNGENAVPGSWPWQVSLQDNTGFHFCGGSLIAPNWVVTAAHCKVTPGRHFVILGEYDRSSNAEPIQVLSISKAITHPSWNPNTMNNDLTLLKLASPARYTAQVSPVCLASSNEALPAGLTCVTTGWGRISGVGNVTPARLQQVVLPLVTVNQCRQYWGSRITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTENCNVQAPAMYTRVSKFNTWINQVMAYN
Protein: Sll1785 protein (P73600)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- Uncharacterized protein sll1783
- Sll1358 protein
- Probable ketose 3-epimerase
- histidine kinase
- Sll1306 protein
- Sll1305 protein
Sequence:
MLLKVKLWGIGLVLTLTLGTILFLQNFSVAAETEIHTFDDIPMPKLADPLLIYTPANEIFDIASCSAKDIGFAIAHAQIPPGGGPMPHIHYFINEWFWTPEGGIELFHSTKQYPNMDELPVVGGAGRGDLYSIQSEPKQLIYSPNHYMHGFVNPTDKTLPIVFVWMRNEVAPDFPYHDGGMREYFQAVGPRITDLNNLPELTNAQRAAFASEAPKYGINQSSYFMEYVNTISDKLPAQIAKLKNDKDLERMVEVIEAFNRGDKSVTCS
Protein: RAC family serine/threonine-protein kinase homolog (EC 2.7.11.1) (P54644)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Predominantly involved during the aggregation to control cell polarity and chemotaxis. Phosphorylates talB, gefN, gefS, PI4P 5-kinase and gacQ.
Interaction partners:
- cAMP-dependent protein kinase regulatory subunit
- Probable serine/threonine-protein kinase pdkA
- Probable serine/threonine-protein kinase DDB_G0288795
- Protein pianissimo A
- RapGAP/RanGAP domain-containing protein
- Protein raptor homolog
- Protein LST8 homolog
- C3H1-type domain-containing protein
- Leucine-rich repeat protein lrrA
- Ras-like protein rasD
Sequence:
MSTAPIKHEGFLTKEGGGFKSWKKRWFILKGGDLSYYKTKGELVPLGVIHLNTSGHIKNSDRKKRVNGFEVQTPSRTYFLCSETEEERAKWIEILINERELLLNGGKQPKKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLLTNEGHICMTDFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPEKRLADPNLIKRHPFFRSIDWEQLFQKNIPPPFIPNVKGSADTSQIDPVFTDEAPSLTMAGECALNPQQQKDFEGFTYVAESEHLR
Protein: Cathepsin K (F6KMR2)
Organism: Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus)
Interaction partners:
Sequence:
EKTGQLMDLSPQNLVDCVTENDGCNGGYMTNAFKYVVDNEGIDSEEAYPYIGQDQPCRYNSTGMAAQCKDYKEVPEGNEHALAIALFKHGPVSVGIDATLSSFQFYTKGVYYDRNCNKEDINHAVLAVGFGQNTKGKKYWIVKNSWGDTWGNKGYIMMARNRDNLCGIASLASFPVM
Protein: Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) (RNA polymerase II Mediator complex protein pmc2) (Q09696)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 27
- Mediator of RNA polymerase II transcription subunit 20
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 6
Sequence:
MDRPHLFSEVHFRRNASNPNQINWTRYWIDCLSSVPWNDISVTGFEYLAKKYGLEVFQDSSKPNEVVLSLAGKIILIDITVPINASPKDINVVLAFANASGEQYNNPVAEKLLKDAIYNCNTPLFEKNVKWLATFDHSSPSVQQSCFQYLDSLSSSLNAIYEAELSLLAQEENVIMHGNGKPLSNYEGQLGLRIVYWKLLDKTYSTQIFMDNLSHESLPHLLFGYNLLNSPPILQSSKINWALENTLTPIPTTMELVFDDINLIIPEQGVKPLLDLLHVHDITIPWPVQNYSHMLGLPSKSTVNYKFINKNQAIQLTGFDVSARSLRHVPFHHPKQIRGILAIVRQYLLLQLILENIKSADLAETAASSSLHLSLYFKEHPIVHAQYQEINKLNNSEQIIIVLSVLSDGRLNVDYMSSGGKELSKQQSHVFQKLIQQTCNIGLAIEVFIKKVVN
Protein: Probable multidrug ABC transporter ATP-binding protein YbhF (P0A9U1)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably responsible for energy coupling to the transport system.
Interaction partners:
- Probable multidrug ABC transporter permease YbhR
- Probable multidrug ABC transporter permease YbhS
- UPF0194 membrane protein YbhG
- Inner membrane transport permease YhhJ
- HTH-type transcriptional dual regulator CecR
- sn-glycerol-3-phosphate import ATP-binding protein UgpC
- Uncharacterized protein YhiI
- Lipopolysaccharide export system ATP-binding protein LptB
- Lipoprotein-releasing system transmembrane protein LolE
Sequence:
MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGAGKTTLMRMLAGLLKPDSGSATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLNLYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVLLLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQGEPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPDDIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMDLKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGLKSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVEKGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQLIHDWDKEHSNE
Protein: Polyamine transporter (Putative amino acid permease) (Q5C8V6)
Organism: Leishmania major
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MRHARERSGATDGAHAGDGDLVHASSQIKDVVSVNGISLGCGGIEDEKLATAANGKSVRVRRNVEVIFHPELRRTKEVIRRPEWVRRAGECVAHRGSLSTIALFGIMFANCVGGGYGFEDGIGSAGPLITLIVCGILPWMWAFPTGLAVAELSTAVPSNSGVLMWTNAAFPPFMSFMCILATIFITFIGNATYPNLTAEYAQQLGNLKLAPVAGVKVGVVALCCILNCVGVEIVGSSSIILCAITILPFTLLTVIQLFSKGFNRAVLYVDVKKVNWAEFFSILSWNYANIENAGAVVEEVANPRRALPKAMMMLMLSTYVGYVMPMLAGVSAMGVDQDYSKWKAGHWPEVAKVIAGDWLKYMLFAGALLSGIGFTLTSMCCTSRLLAGMGTMQMFPKKVSRVIGYYHPRLGTPIPAIFINSLVTLVFSVSMEFTSVVSLCQSIYCLRMLLIYASLVKMRIDYPNLPRPYALPFSTCTTALVLLPAAAFSLMASIVSAMTSLGIGMALVGFVVVGSGVSWLYCRIFARNGFQGVIVQCEVSSGDDAEAGAADSANDSALSEGIFYADEERNSGEPVDDLLLGILPMPLAAPGPLASTVLPRGSEVSSSQWHVRHGMTDRDAIGSQAGEEMIGMEYALQDGPSTDIMVVNSSATAHALGSSTAVCSPTSSFHTYRVACGVETTMRHRHRARSHGAGGGGGGATNSGNYGPAVSGEESGEDPDITPAEHSGGGFTLSATGLPGQVLSTSPPQLILSPQQVLLNVPAAGSWSSSRSPTPASGPRSPILTSAINMSTTRKPPPPPTSL
Protein: Insulin-like growth factor 2 (Insulin-like growth factor II) (Q2F6J3)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU000406}.
Interaction partners:
Sequence:
MGITAGKSVLVLLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSRINRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSASTT
Protein: CHK kinase-like domain-containing protein (Q9VWY5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSDALEEPPLYLTPQFFRRTLEHGLQQLDLQVIGVQLTNLTRGGENYCSNIYRAQIKYRNAESCAMETSLIVKSMPDEKQAILARLHIYNKETLFYMHIKPKLEALMWRAVDSFSAWTLAPKHYYSTTQPEQTIILEDLCAAGYQLKCRQLGLDFDHAALVMAKLAEYHALTMVMAEREPETIVDRYPFGLLHMDAINSEPFKLLFGTQLLKLAALVGDCEGFGGITTKLYRYHEHFTERVLKAVYPLRGNHNVLNHGDLWVNNIFFKYDAEYTVQQVKIIDFQLCFYGSLGFDINYFLNTSLELEVLRDRRQELVDIYYRSLVDCLKHLPWSKELPSYEDIMDEIRKREAYGFFVAFGFFPLMSMIGVDSEDNSLKNFHDETFARQKVQLMFEGNTRTLESLKCTLKRLDELKLFD
Protein: Bone morphogenetic protein 7 (Bone morphogenetic protein 7a precursor) (Q9PTF9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- Chordin
- receptor protein serine/threonine kinase
- Noggin-1
- Noggin-3
- Serine/threonine-protein kinase receptor
- Noggin-2
- Receptor protein serine/threonine kinase
- Receptor protein serine/threonine kinase
Sequence:
MTLKMFPVHLISTLIVACGCSVLADAMQANFTMDNDIQSSFIQRRLKSQERREMQREILSILGLPQRPRPLLHERHTAAPMYMLDLYNAILEDGDRRGGLVYSYEPAYTTPGPPLVTQQDSRFLSDADMVMSFANTVDPEEDLQLYHQHRREFRFDLSRIPPGETVTAAEFRIYKDFVRERYENETFHVSVFQVLQQQHRRELYLLDSRVVWAAEEGWLVFDLTVTSNHWVINPGQNLGLQLLVETSHGARMNPRRAGLVGSSGAQNKQPFMVAFLKASGIHLRSVRSASGGKQKGHHRTKNAKPGAAHSQVALKTAEATEGASIDPKQGCKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECVFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLHGISVLYFDDSSNVILKKYRNMVVRACGCH
Protein: DNA cross-link repair protein PSO2/SNM1 (EC 3.1.-.-) (P30620)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for DNA interstrand cross-link repair. This requires cleavage of cross-linked DNA to generate DNA double strand breaks (DSBs). This protein has 5' exonuclease activity on single-stranded and double-stranded DNA, which appears to be necessary for the processing of DNA double strand breaks prior to ligation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Exodeoxyribonuclease 1
- DNA polymerase zeta catalytic subunit
- ATP-dependent DNA helicase II subunit 1
- Protein CFT1
- ATP-dependent DNA helicase II subunit 2
- mRNA 3'-end-processing protein YTH1
- Pre-tRNA-processing protein PTA1
- ATP-dependent helicase HRQ1
- DNA repair protein RAD2
- DNA mismatch repair protein MSH2
Sequence:
MSRKSIVQIRRSEVKRKRSSTASSTSEGKTLHKNTHTSSKRQRTLTEFNIPTSSNLPVRSSSYSFSRFSCSTSNKNTEPVIINDDDHNSICLEDTAKVEITIDTDEEELVSLHDNEVSAIENRTEDRIVTELEEQVNVKVSTEVIQCPICLENLSHLELYERETHCDTCIGSDPSNMGTPKKNIRSFISNPSSPAKTKRDIATSKKPTRVKLVLPSFKIIKFNNGHEIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSWNNPDENPIKKTLYCSKITAILVNLKFKIPMDEIQILPMNKRFWITDTISVVTLDANHCPGAIIMLFQEFLANSYDKPIRQILHTGDFRSNAKMIETIQKWLAETANETIDQVYLDTTYMTMGYNFPSQHSVCETVADFTLRLIKHGKNKTFGDSQRNLFHFQRKKTLTTHRYRVLFLVGTYTIGKEKLAIKICEFLKTKLFVMPNSVKFSMMLTVLQNNENQNDMWDESLLTSNLHESSVHLVPIRVLKSQETIEAYLKSLKELETDYVKDIEDVVGFIPTGWSHNFGLKYQKKNDDDENEMSGNTEYCLELMKNDRDNDDENGFEISSILRQYKKYNKFQVFNVPYSEHSSFNDLVKFGCKLKCSEVIPTVNLNNLWKVRYMTNWFQCWENVRKTRAAK
Protein: Dynamin-binding protein (Scaffold protein Tuba) (Q6XZF7)
Organism: Homo sapiens (Human)
Function: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17015620}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q6TXD4}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q6TXD4}. Synapse {ECO:0000250|UniProtKB:M0R4F8}. Cell junction {ECO:0000269|PubMed:17015620}. Note=Localizes to the apical junction, colocalizes with TJP1. {ECO:0000269|PubMed:17015620}.
Interaction partners:
- Actin nucleation-promoting factor WASL
- Myc box-dependent-interacting protein 1
- Bridging integrator 3
- Cell division control protein 42 homolog
- Amphiphysin
Sequence:
MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGARGFFPSSCVRELCLSSQSRQWHSQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVEETMALPQEGSLARIPETSLDCLENTLGVEEQRHETSDHEAEEPDCIISEAPTSPLGHLTSEYDTDRNSYQDEDTAGGPPRSPGVEWEMPLATDSPTSDPTEVVNGISSQPQVPFHPNLQKSQYYSTVGGSHPHSEQYPDLLPLEARTRDYASLPPKRMYSQLKTLQKPVLPLYRGSSVSASRVVKPRQSSPQLHNLASYTKKHHTSSVYSISERLEMKPGPQAQGLVMEAATHSQGDGSTDLDSKLTQQLIEFEKSLAGPGTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQELPERRKALRPPPPRPCTPVSTSPHLLVDQNLKPAPPLVVRPSRPAPLPPSAQQRTNAVSPKLLSRHRPTCETLEKEGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLEEKQDESSRAETLEDLKFCESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAENPEQRMLEKRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQFERVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSLLKVAGREGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGLPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFNPSSMAVSFTSGSCQKQPQDASPPPKECDQGTLSASLNPSNSESSPSRCPSDPDSTSQPRSGDSADVARDVKQPTATPRSYRNFRHPEIVGYSVPGRNGQSQDLVKGCARTAQAPEDRSTEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT
Protein: Hgt2p (Q59VZ0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- High-affinity glucose transporter 1
- Hgt12p
- Uncharacterized protein
- Bifunctional protein GAL10
Sequence:
MSSKIERIFSGPALKINAYLDKLPKIYNVFFIASISTIAGMMFGFDISSMSAFIGSGPYMKFFHSPGSDIQGFITASMALGSFFGSIASSFVSEPFGRRLSLLICAFFWMVGAAIQSSSQNRAQLIIGRIISGVGVGFGSAVAPIYGAELAPRKIRGFIGGMFQFFVTLGILIMFYISFGLGHINGVASFRIAWGLQIVPGLCLFLGCFFIPESPRWLAKQGQWEAAEEIVAKVQAHGDRENPDVLIEISEIKDQLLLEQSSKHIGYATLFTKKYIYRTFTAIFAQIWQQLTGMNVMMYYIVYIFQMAGYSGNSNLVASSIQYVINTCVTAPALYFIDKIGRRPLLIGGATMMMAFQFGLAGILGNYSVPWPDSGNDSVNIRIPLDNKSASKGAIACCYLFVASFAFTWGVGIWVYCAEIWGDNRVAQRGNAISTSANWILNFAIAMYTPSGFKNISWKTYIIYGVFCLAMGTHVYFGFPETKGKRLEEIGQMWEENVPAWRSRSWQPTIPIASDAELARKMEVEHQEDKLMNDDSNSESKENQV