wanglab/gogpt-training-data huggingface dataset:
Protein: Serpentine receptor class alpha-13 (Protein sra-13) (Q20618)
Organism: Caenorhabditis elegans
Function: Chemosensory receptor that negatively regulates RAS/MAPK signaling during vulva induction and the negative regulation of olfaction of volitile attractants. Required for the suppression of vulval induction in response to food starvation. Signaling acts through the GPA-5 G-alpha protein subunit.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- G-protein coupled receptors family 1 profile domain-containing protein
- Serpentine receptor class r-10
- Serpentine receptor class r-10
- Serpentine Receptor, class I
- Serpentine Receptor, class D
- Serpentine Receptor, class J
- Serpentine Receptor, class J
- Serpentine Receptor, class T
Sequence:
MAIISSVNRTCASESLLELYRSYKYILSTSFNIIIPIISLFFLVYAIKQLCAQSIIQYSTRVLLITTILFAVCHQIAYFCFKADLLYTMLFKLDQPCNLQHSSYDCRFITIATTTSNCGMALVQLAMSIDRVFALKFNRVYYKLKSIPGITLALITLSISFSMFFILTIDDPLSGYVNHCGFYPTYSQDKFHIFLDVTLYLAVFNFVFDIGLMYYSYQEILWKRSYSFVNRFQSRISLKCTQAIFIISICQCISNVLYSGLLSLLMKLGRYMSSADYNLSLSLAYTTPYSCLILPILICKVLEYIKKQRTVGILSLRNQKQSMEGHMAMINSAWK
Protein: Protein LIKE COV 2 (Q9C8C1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Polyadenylate-binding protein-interacting protein 7
- GDSL esterase/lipase At4g26790
- Tubby-like F-box protein 9
Sequence:
MAEGKEATTSSLSQGLTPHQDPDDAPKSPPNSPNSSTRKACYGVLQSWVSKKFMTGFVVLFPVAVTFLITWWFIQFVDGFFSPIYENLGVDIFGLGFITSVLFTFFVGIFASSWLGSTVFWLGEQFIRRMPFVKHIYSASKQISTAISPDQNTTAFKEVAIIRHPRIGEYAFGFITSSVTLQTDHGEEELCSVYVPTNHLYIGDVFLVSSEEIIRPNLSIREGIEIIVSVGMTMPQVISHVDRTTNRTPHQHSLRVPLNRL
Protein: Pseudouridine kinase (EC 2.7.1.83) (P30235)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP).
Interaction partners:
- Pseudouridine-5'-phosphate glycosidase
- Putative pseudouridine transporter
- Probable fructoselysine utilization operon transcriptional repressor
- Threonine dehydratase operon activator protein
Sequence:
MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGRNIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMNISNAITAEYLAQHGEFIQRAKVIVADCNISEEALAWILDNAANVPVFVDPVSAWKCVKVRDRLNQIHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDISGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESVRFAQGCSSMALSCEYTNNPDLSIANVISLVENAECLN
Protein: Seminal fluid protein 36F (Seminal fluid protein 36F, isoform B) (C4NAP2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Seminal fluid protein 51E
- Sidestep II, isoform A
- SET and MYND domain containing, arthropod-specific, member 9, isoform A
Sequence:
MSVKATLIILAIFLFVRKFPHNTEKCSPLNCINDD
Protein: Zinc finger protein 496 (Zinc finger protein with KRAB and SCAN domains 17) (Q96IT1)
Organism: Homo sapiens (Human)
Function: DNA-binding transcription factor that can both act as an activator and a repressor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
Interaction partners:
- Histone-lysine N-methyltransferase, H3 lysine-36 specific
- Transcription intermediary factor 1-beta
- Arrestin-C
Sequence:
MPTALCPRVLAPKESEEPRKMRSPPGENPSPQGELPSPESSRRLFRRFRYQEAAGPREALQRLWDLCGGWLRPERHTKEQILELLVLEQFLAILPREIQSWVRAQEPESGEQAVAAVEALEREPGRPWQWLKHCEDPVVIDDGDSPLDQEQEQLPVEPHSDLAKNQDAQPITLAQCLGLPSRPPSQLSGDPVLQDAFLLQEENVRDTQQVTTLQLPPSRVSPFKDMILCFSEEDWSLLDPAQTGFYGEFIIGEDYGVSMPPNDLAAQPDLSQGEENEPRVPELQDLQGKEVPQVSYLDSPSLQPFQVEERRKREELQVPEFQACPQTVVPQNTYPAGGNPRSLENSLDEEVTIEIVLSSSGDEDSQHGPYCTEELGSPTEKQRSLPASHRSSTEAGGEVQTSKKSYVCPNCGKIFRWRVNFIRHLRSRREQEKPHECSVCGELFSDSEDLDGHLESHEAQKPYRCGACGKSFRLNSHLLSHRRIHLQPDRLQPVEKREQAASEDADKGPKEPLENGKAKLSFQCCECGKAFQRHDHLARHRSHFHLKDKARPFQCRYCVKSFTQNYDLLRHERLHMKRRSKQALNSY
Protein: Flagellar Member 5 (Q38D82)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTNAQSPVLLPSQFMPQKEDTRSTDAYEELVANYISLKAKMNPLLSSQVETIRFSEVVDLRRNYIGAVGLQAVTSLLVKNDKLKELIVPCSGLNNDSVAFFCRAMIKHRSLEKLDFSGNTISLTAGLAVLSLLQHNPGIVHADLSNTQVPEGVMKKIEKALERNRLCETAGNASGKEVATREECAEGRCAIEAFRVDAEGNRITGTVVEEKPATSTFASTMRETVRKADWMQKETVALDRLSTFTKSVVASGNKFVPLPHIESGWRLLEVAILAPPFIFHSETELLLNRVFPLLNEEFVGSRVHLNPLFSPPEEPAGVCLKNLRFAIQVDVLRDVEKSRFLTLELIGDREGDYRAMTANDMLNRQSLGAPYRLRSMSSQVVPSESPQAPPLQPVLHAAHRRAMEVSSWRIIATRKGTRKLGIPPSLAPLLTEEPPIEHPDYLQRQVRRTCTVAAKEVCPSQLICCDAAVKEKKWQEHQVFKQYVVEGADTPELVIPDYNAEFDRCGADGQVHLKHLEEFCQAVYERIQRVMSAHFPPVKEGHPSYFYGSAEKEKVLQKLKQYHEWLHTLLFSRLHCHLVKKNITNRLDLYVIAPPSRNSLLLHSADISAVSELISSFTWGLLTKSAQKCRVAYHTTHSALLTEEPTELRNIICTIIHQLYPNQEVYRSAIGEVDLGRLQKLFLDTITEKGKMAEQLNGNGDAKSDGNEKVITVVILDGIDNVIAPVEPCTALRMCEKTGKDVWEAPALRPGAFACLPYCLSRNVRLVLGCETDSTLYKQLQTRGKDSVEFLPVGNMTPNDFDDMLRPEVMGRIGVTLSDDDFMLIRQKEQALCPEYVLQVVDVLRSFNEAPGLGTHAIKVSLPGTVDGMVQQVYDKLNDSFGTALIRKCTRLLVCSRWGIHEPQLRAMLQLTCTRFNRLIRMMRPLIYSGTVCNIGTEGGNALNVRVCIRSRAFRELIKREDVLEEGSESDYKVWHGMLLRCYHDVVHEVLGREKGEVLLGLSSTNPFERTAVKELPYHAVEAQEAHVIHRVVLTMPYLMVVYRNSLGYHLVRELISAFNSFHESYEVGEYTFDEDVDVTTRQKPTSILRLRDYIYFLRQYNSKLTKYPHLVVGTAIESGNRYPYVSMDARAYVTQMLTITCPLRQRRLSFFTTMALSAKKQIHQRTITACCIPSRGKRIITASADRSICAVHPVTGAVEVQVRRSPSAVESLLWCETGAYHATVCHDRTLLIYDSAEMNIVSRCDGGTFGAPLTSVAFSARGRFYLVTTEDLYLRAYDTEKTSVVLDVDQRHFLEKCEMADINRIRGFTTVLPHRSEDEIFYSVCHNVVIMWQLSTARNAFEKERTFSLPFSVESGKMIRSCTHFLLYPAPFPPTASGHLPPPRQLRLCDVEAGREVAVLVSSCNHVVYQLSSNERMVAAGLEDGSVAVYRLPWSRIRQVGDAAVDVLTVTPTNHFSAFRYSALPTVSGLRFKWGDDGIFALGNDKQLKFWVLPRKHMPFPVPDDDTVDEMQGESIELMEEEPEDEVIEGVADAEFVHECEITAWDVATEPSDKAAAVVIGDPTGRLTMLRMWSPAT
Protein: Uncharacterized protein (Q3URC6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
DFCILSFSFVFKPESFWNSASFNTEASYLHFPTFRGELTADVHFLFKTTISSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCELTIQSPTPFNDNRWHHVRAERNVKGASLQVDQLPQKTQSTPADGHVRLQLNSQLFIGGTASRQKGFLGCIRSLQVNGMALDLEERAVMTPGVEPGCSGHCSSYGHLCRNGGMCQEKHRGIACDCAFSAYDGPLCSYEISAYFETGSSVTYNFQEYSTLSANTSYLASSLHGDVILSRETITLSFRTTQTPCLLLYVTSFYEEYLSIILANNGSLQVRYKLDRHRNADAFNFDLRNLADGHFHQLTINREEAVVSVEVNQSTKRQVILSSGTEFNAVKSLVLGKVLEPLDADPETQQAAAQGFTGCLSSVRFGLEVPLKAALNQNRARVTIQGSVAAAAHCAEGPGSAERKLSPGPSMDAGHSGSAEDRQPLPNTDRSDPGVIGGITAVVIFILLCVSAIAIRVHQQRRLHQKNESTVSKTEEC
Protein: Peptidyl-prolyl isomerase CWC27 (PPIase CWC27) (EC 5.2.1.8) (Complexed with CEF1 protein 27) (Rotamase CWC27) (Q02770)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pre-mRNA-splicing factor CWC22
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor CEF1
- Pre-mRNA-splicing factor CWC24
- Pre-mRNA-splicing helicase BRR2
- Pre-mRNA-splicing factor BUD31
- Pre-mRNA-processing protein 45
- Pre-mRNA-splicing factor CWC26
- Pre-mRNA leakage protein 1
- Pre-mRNA-splicing factor 8
Sequence:
MSSNIEPQTTAKCILYTTKGNIAIELWAKECPETCKRFLSMLSDGTFTNGEFKELKPTQWLMFNANSTGEYRTVAEEKNPRIRFNRDGLLGWDRRRNTWFITVLADSKHVLNDCNVFGKIVGKSIYIFREILGGEIEASSRDNDVKRFMYPAVLKDVEITIPFFEDIFGSKRRLEDNEKKEQEPAKKLVKSAKVKMVYEDEQEDDDGDVQKLKPRKRMILPAWIKDDSRSEGIKLDASLDQPQEALIREKTELHDNVDEATTKETESQENIKEEPMDKRERETLAMLSKFQERIKNKNILK
Protein: Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) (P52296)
Organism: Rattus norvegicus (Rat)
Function: Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. In association with IPO7, mediates the nuclear import of H1 histone. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Imports SNAI1 and PRKCI into the nucleus (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:7604027}. Nucleus envelope {ECO:0000269|PubMed:7604027}.
Interaction partners:
- Importin subunit alpha-5
- Sterol regulatory element-binding protein 2
- GTP-binding nuclear protein Ran
- Importin subunit alpha
- Snurportin-1
- Importin subunit alpha
- Importin subunit alpha
- E3 SUMO-protein ligase RanBP2
- Importin subunit alpha
- Importin subunit alpha
Sequence:
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIRLLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVSQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLSTCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQAMPTLIELMKDPSVVVRDTTAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLWKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAECQVCLAAVGLVGDLCRALQSNILPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDITLAIGGEFKKYLEVVLNTLQQASQAQVDKSDFDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
Protein: Large ribosomal subunit protein bL33m (54S ribosomal protein L39, mitochondrial) (YmL39) (P36533)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16823961}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein bL36m
- Small ribosomal subunit protein uS15m
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein bL28m
- Small ribosomal subunit protein bS6m
- Large ribosomal subunit protein uL16m
Sequence:
MVKVKSKNSVIKLLSTAASGYSRYISIKKGAPLVTQVRYDPVVKRHVLFKEAKKRKVAERKPLDFLRTAK
Protein: Endoplasmic reticulum transmembrane protein (Q9LSH0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU367026}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU367026}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MALQWLILSYVVAAEVAIAVILTLPYPMLLKKRIVSLISLILNPAASIVAFAGFQLLDIYWKNEHRLLCSSEVCTTTERDRHEKSVYKAQRNGVLCAAGILLYWCIFRICKYHKDLERLEQLEKRYKDE
Protein: Ubiquitin activating enzyme, putative (Q385Q1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLNAALYERTQIIIGDEGVKRLHQVNIFLAGVGGVGGHCAEALVRGGVGKITICDYDVVSATNKNRQLVAMDSTVGKSKVDVLARRLQDINAHCRVTALEALLLPEDMEDFLTRQRYDYVVDCIDSVECKVALLSTAVRLGLRTYASCGAGGRVDPSLVRVSDIFDTVNDALARCCRSELRKRGVGPGAITAVHSSELGCPPLEPQRQEAGGRDRAINGTVSYMPPLFGLLLASSVLRHAVDPVKAEKEAERRLKKAKKEEARAHKKASRLVGVKRC
Protein: Chaperone protein LppX (V9TSX0)
Organism: Paenibacillus barcinonensis
Function: Is required for the expression of the adjacently encoded xylanase Xyn11E in an active form. LppX seems to act as a specific chaperone necessary for the correct folding of the xylanase during secretion across the cytoplasmic membrane.
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
Sequence:
MRKWLIFLLIAAVAGLSACSTSGNTTVSDDLVLVEGGAFKTSKSSYSDKNVTLSDFYIGKYEVTQKQWMDVMGDNPSGFKGEERPVERVTWYDAIEYCNARSIKENLKPYYTIDKETTDPDNKNENDNIKWTVTINEGANGYRLPTGAEWEYAASGGQKSQNFTYSGSNNPDEVAWYWMNAGEKPLTGDWNWPAIENNRNQTKPVGQQKANELGIYDMSGNVREWCWEWHSHPETPENTWRISKGGGWVSSVNTAEISYPGKFDANGLGPDQGLRVVRSK
Protein: Protein kinase, putative (EC 2.7.1.-) (Q384D4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Serine/threonine-protein kinase, putative
Sequence:
MSTGKIIGDHRYLIEGLIAKGTFSNVHRCVDLTTDKVYAVKVISKSVIESQNMSVTVVREVSAMEAAPPSPYLVRLVDKLVSSRNYYLVMNVVEGCTLLDVIEKKYRPRPPLRWVRSIFRQLLNGLYTLHGANVVHRDIKPENLLLNRSYTRLVISDFGFACCAPPGRSLHHSCGTMNYCAPELLVPKPAYDGRKVDVWAAGVTLYVMIFGVHPFQARKEGCADSLAEVITSGAYTLPHSLQPELEHLLSVMLEPDPALRWSVRKLLRHVWVLGGMVGGVTGRSSLRLTTPTPGSTGVANRDANTPEDYVVRSRFARALRADDTDPSARQFRSCPDLRREMNNFLDACDSDGEDAEWDGDFSNGNSTHDGYTKFSSLNVSLTDIERGRQPSDLDGFSESTAFATNGSYSSLFSADQLLLDPDETPDTPKGDFLLTVRVIVNFALFCTTLVIVAALRFLFDVPVRDLPLPPFVISIMEYLLVPPHERLAQSFEVRRMRHRFPCAALRRLVASAERAIQRSSWCRRIMPVRGVDEGTDVPLGTGRRGIVLRWLEKN
Protein: Uncharacterized protein (Q19280)
Organism: Caenorhabditis elegans
Interaction partners:
- Lipoma HMGIC fusion partner-like 3 protein
- Protein unc-50
- Immunoglobulin domain-containing protein oig-4
- Uncharacterized protein
- CUB domain-containing protein
- Resistance to inhibitors of cholinesterase protein 3
Sequence:
MVGNVLLLLIYHITLATSSQWTSSQFPDLRGPTVNQCVAVLPRNKQQLYVCDPDHMLNNTQAMQLNIQLQELAVGTPCHCQRRSQCTTGIEGSGGKEGLHGFIVSIAIVKNLYMHMHSPSDTQLTERAEAFCRALEGRWALGDCGNSVIVFVWQHYKKMVIWPARLAEKYITAEERKAILTKVNDYAQTDDWFPALSTIIKEISNELNGDPEPRFDTGTLSLLLSVGLAVGLTVFITCCVCAFRCCGNVKTRERRKSVERAMDNLRNSVIRRGSQFRRFDCQCIPMMCVHIMPLCVTL
Protein: lipopolysaccharide heptosyltransferase II (EC 2.4.99.24) (O05196)
Organism: Pseudomonas aeruginosa
Interaction partners:
Sequence:
MRILIVGPSWVGDMVMAQTLFQCLRQRHPECVIDVLAPEWSRPILERMPEVRQALSFPLGHGVMDVATRRRIGRGLRGQYEQAILLPNSLKSALVPWFAGIPKRTGWRGEMRYGLLNDIRKLDKQRYPLMIERFMALAFEPGVELPKPYPQPRLRIDDGSRQAALDKFALSLDRPVLALCPGAEFGEAKRWPAEHYAAVAEAKIRAGWQVWLFGSKNDHPGGEEIRQRLIPGLREESFNLAGETSLAEAIDLMSCAGAVVSNDSGLMHVAAALDRPLVGVYGSTSPQFTPPLADRVEIVRLGLECSPCFERTCRFGHYNCLRELPPGLVLQALERLVGDPAEVAG
Protein: Trimethylguanosine synthase (Cap-specific guanine-N(2) methyltransferase) (Q54IS7)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Small nuclear ribonucleoprotein F
- Probable small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein E
- Probable small nuclear ribonucleoprotein G
Sequence:
MDKRIENTKSKINSPEFQSFNKVKKKRIRRQLKKLEITKKRFEKIKQRANKSRENNENESENESENESENESENLDEEEEENENESESETKDVENVNGKQKENEKEKQKENENENKFDTLIKNNNNDIMSKYYSQRYRLFSKFDEGIVLDQESWFSVTPELIAQHIAERCSCNTLVDLFCGAGGNTIQFSFTCNVVVSVDLDPMKLLMAKHNSWVYGHSSENTNIEFVNSDAMNLSNLKADVIFLSPPWGGPNYTDSSIFHLDSMTPNGFEIFKNAIKVTPNVVYFLPKNTSKVDIAKLALISKENGGSELCEIEENYINEKLKTITLYFGSLVNNNNKNYESYQ
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (13 kDa differentiation-associated protein) (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2) (Q9UI09)
Organism: Homo sapiens (Human)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:12611891}; Peripheral membrane protein {ECO:0000255}; Matrix side {ECO:0000305}.
Interaction partners:
- NADH-ubiquinone oxidoreductase chain 4
- Cytochrome c oxidase subunit NDUFA4
- NADH-ubiquinone oxidoreductase chain 3
- NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial
- NADH dehydrogenase 1 subunit C2
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase 1 beta subcomplex subunit 3
- Acyl carrier protein, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
Sequence:
MELVQVLKRGLQQITGHGGLRGYLRVFFRTNDAKVGTLVGEDKYGNKYYEDNKQFFGRHRWVVYTTEMNGKNTFWDVDGSMVPPEWHRWLHSMTDDPPTTKPLTARKFIWTNHKFNVTGTPEQYVPYSTTRKKIQEWIPPSTPYK
Protein: Ubiquitin carboxyl-terminal hydrolase A (EC 3.4.19.12) (Deubiquitinating enzyme A) (Ubiquitin thioesterase A) (Ubiquitin-specific-processing protease A) (P54201)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Required for development but not growth.
Interaction partners:
- Beclin-1-like protein B
- Ubiquitin-like domain-containing protein
- Ubiquitin carboxyl-terminal hydrolase
- Ubiquitin-ribosomal protein eS31 fusion protein
- ubiquitinyl hydrolase 1
- Ubiquitin-ribosomal protein eL40 fusion protein
- Myb-like protein H
- Ubiquitin hydrolase B
- Ubiquitin thioesterase OTU1
- UV excision repair protein RAD23 homolog
Sequence:
MELFPELKNIKVPTEKSRLWKDECCYCFDTPENGEGLFIDLIGLLAFSKKYVQLNHQKTHHHLYLNFKKVAIVNEKVKSPTIENGGEEKPPKKLAIGVEGGFNVEDEEIKYEEHYKLYIFPDDKFLELSDPIIPENVRVCCEKIKTLNSQSRKEEIVSWNAESVFPSAFAESIIQLDNNTKKIDPKGPWRCDIEGCDKVENLWLNLTDGFIGCGRKYADGTGGNGHAQEHFNQTQYPISVKLGTITKDHADVYSYPEDDMVSDPLLFQHLTHWGLNPNVMVKTEKSMAELELDQNLNFEFGKIQEKGKLLENVFGPGLTGIENLGNSCYMSSVIQMIFAIDSFQTRYLKDREASFKDITQDPTQSFEIQMSKLAHGLLSGDYSIPLSKPSKNANEESEAATQIGIAPKMFKSLIGASHAEFSTMKQQDAHEYLQYLLEYIERAEHSRPSWIQQANPTRLFQFHNEDRIECGSSGQVKYTRRLENILSVPVNLDDATNKQEVAQYEETLKQQNGVRQKDQEEIRPIIPLVSCINGFVEPYRVEDFLSPATGVKTFSLNSSRMATFPEVLIIHLKKYTYNADYTPKKLNVFMDVPDIIDIDSLRGRGIKEGEVPLKEGTINTTTKVPEPSFNQEVLDTLLSMDFPLVRCKKALLATGGKDAELAMNWIFEHTEDPDIDIEQTPVNNNNNNNNSSNSNDKLFVFNSQDVDNIIGMGFTDSQAKLALKNTKGNLERAADWLFSHIDNLDELVAKDNASTSSINPSLIPQSTTSLQPVSDGVGKYELLGFISHLGNNVTCGHYVCHIKKNNRWIKFNDRHVQLSEQPPKELGYIYFYKRQLN
Protein: Polyubiquitin 9 [Cleaved into: Ubiquitin-related 1; Ubiquitin-related 2; Ubiquitin-related 3; Ubiquitin-related 4] (Q9FHQ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- E3 ubiquitin-protein ligase UPL4
- E3 ubiquitin-protein ligase UPL3
- Protein NBR1 homolog
- E3 ubiquitin-protein ligase PRT1
- Ubiquitin-conjugating enzyme E2 13
- SUMO-conjugating enzyme UBC9
- E3 ubiquitin-protein ligase UPL2
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL42z/eL42y
Sequence:
MSMQIHAKTLTEKTITIDVVSSDTINNVKAKIQDIEGIPLDQQRLIFSGKLLDDGRTLADYSIQKDSILHLALRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGVPPDQQRLIFAGKQLDDGRTLADYNIQKESTLHLVLRLRGGMQIFVRTLTRKTIALEVESSDTTDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLCGGMQIFVNTLTGKTITLEVESSDTIDNVKAKIQDKERIQPDQQRLIFAGEQLEDGYYTLADYNIQKESTLHLVLRLRGGECFGFIFLFLLCFNS
Protein: Putative mitogen-activated protein kinase 14C (MAP kinase 14C) (MAPK 14C) (EC 2.7.11.24) (MAP kinase p38c) (P83100)
Organism: Drosophila melanogaster (Fruit fly)
Function: Kinase involved in a signal transduction pathway.
Interaction partners:
- Activating transcription factor-2
- mitogen-activated protein kinase kinase
- Mitogen-activated protein kinase p38b
- Mitogen-activated protein kinase p38a
- Forkhead box protein O
Sequence:
MPEFVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILRGLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYTKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQRCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNFENMVLPVKCWKELVSHEIRNFRPDQLDLHF
Protein: Zinc finger protein 976 (A0A087WSF4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
DALTFDDVHIHFTREEWSLLDPSQKRLYQDVMLENYRNLTTIGYNWKDHNIEEHSQNDRRYGRHERSPSAEKPYEYTQWNKAFKYHSHLQKLERNQTRDRHSEVFQHSKVHACQSTLQINKRTNTAQKPYKCNECDKAFLKLKYLRAHERTHSGKKPYECSQCGKAFLHPCYLRIHERTHTGEKPYQCNQCAKAFTLRSQLQSHKVVHTGVRPYICKQCNKAYPQQSYLRKHERTHTGGKPYICNLCDKAYSHQSNLRIHEITHTGEKPYICNLCDKAYSHQSNLRIHERTHTGEKPYICNLCDKAYSHQKYLQIHEKTHTGEKPYKCNQCDKGFAQLRYLRAHERTHTQEKTYKCNQCGKAFAQLTYLRVHERRHSGEKPYKCNECDKAFLQLKYLRLHERRHSGEKPYECNQCGKAFLHPSYLRMHERTHTGEKPYQCNECDKAFLHPSYLRMHERRHSGEKPYECNQCGKAFLQSHYLRMHERTHTGEKPYECNQCGKAFLHLSYLRMHERRHSGEKPYECNQCGKAFLYPSYLRMHERTHSGEKPYECNQCGKAFLHSSYLQMHERTHSGEKPYECNQCGKAFSHSSYLQMHERTHTGEKPYECNQCGKAFLQPHYLRKHEKTHTREKPYK
Protein: AlgZ (Sensor histidine kinase) (FimS) (Sensor histidine kinase YehU (EC 2.7.13.3)) (P77568)
Organism: Pseudomonas aeruginosa
Interaction partners:
Sequence:
MPIRFKPGRSTRPAVQDDFFIPELCEAEALFTLVLLAELLVLVLVLAEPMTPSFNWVRLALASLFVQWIVLLSAALFCRLRPLLARLPVALAGSACCLLVVALTLGCTAVAEHYQLGGELTRAGEVNLYLRHALIALIMSALVLRYFYLQSQWRRQQQAELQARLESLQARIRPHFLFNSLNSIASLIELDPLKAEHAVLDLSDLFRASLAKPGTLVSWEEELALARRYLSIEQYRLGDRLQLDWQVHGVPANLPIPQLTLQPLLENALIYGIQPRVEGGLVQVEAVYREGVFQLCVSNPYDEALESPPSKGTRQALHNIDARLGALFGPKASLSVERRDGRHYTCLRYPCARLMQEA