wanglab/gogpt-training-data huggingface dataset:
Protein: HID-1 (Protein HID1) (G5EG65)
Organism: Caenorhabditis elegans
Interaction partners:
- Dymeclin
- Ubiquitin carboxyl-terminal hydrolase 7
- Nsp1_C domain-containing protein
Sequence:
MGAQGSRVDFKQVVLDVTSKPGKDDETFWDQAWWPDSVNEIFAMISGEDIRKLRDESPKNLATLVYKTVEKLQFSRNHPATIDQKKTINAIRLLTRIVPYLLEDAEWRGYFWSPIPHGDAAKPLAAVLLETLSDLLFCPEFTITHANGQKIDDLSTIDSCEYIWEAGVGSGNKPPMVALHYQNRTEILKLLLTCFAELIYAPVSDETRLRWVIHFTSVTNPHVLPIFTSLLNIVCAYDPVGYGLPYNYLLFNDSREPLVEIALQVLIVCLDKETQPNTDDSGYKDNYFINYLSRIHREEDFDFMLKGITRLLSNPIHSSSSYLPNSTKRVNFHQELLVLLWKCCEINQKFMFYVLKTSDVLDILVPILYHISDARNDSGRVGLIHMGVFIILLLSGERNFGVRLNKPYTAKANINVQTFTGTHADLLILVIHKLITTGNYRLQTLFDCFLTIMVNVSPYMKSLSMVAANKLVHLVEAFSTPWFLFSSPTNPQLVFSLLEVFNNVIQYQFDGNSNLIYTIIRKRNVFYQLSNLSTDAASIAKTLSGRKSKSANRDEMVDQLKSPTSTAPPEIPAADAPAAQTLGGVSTTTGLAATPALASMTGNVGNWEERPESSQDNEWIATQEWADAWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPIVIRRYQTNIGTNHWFRIYMWGVIYLKHTQPPIWYDTDVKLFEVQRA
Protein: 3,4-dihydroxyphenylacetaldehyde synthase (DHPAA synthase) (DOPAL synthase) (EC 4.1.1.107) (Alpha-methyldopa resistant protein) (AMD-r protein) (P18486)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the decarboxylation-oxidative deamination of L-3,4-dihydroxyphenylalanine (L-DOPA) to 3,4-dihydroxylphenylacetaldehyde (DHPAA). Involved in cuticle development (Probable). Probably responsible for the protein cross-linking during the development of flexible cuticles.
Interaction partners:
- monoamine oxidase
- Tyrosine 3-monooxygenase
- Aldehyde dehydrogenase type III, isoform Q
- Aromatic-L-amino-acid decarboxylase
- tyrosinase
- Phenoloxidase 3
Sequence:
MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMDTKASDIDFAWQEIESQLTDLQAEQSLVARKSGNVGDLAQHFQIHLSTENATHEKSQ
Protein: Flavin-containing monooxygenase (EC 1.-.-.-) (Q6NZ32)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Immunoglobulin-like domain-containing receptor 2.
Sequence:
MPGVRKLRVAVIGAGAAGLCAARHLLSRPDTFAAPVVYELTKNIGGTWVYEEKVGHYEDGSPIHSSMYRDLRTNIPKEVMSFPDFPFAKHLSSFVHHTEVRKYLEQYCDHFRLRDYIQFGTSVASVNPVSVKDGWNGLAWNVTSNNGLDHSKSTTERFDAVMVCNGHFYDPYIPAIPGLEKFKGALIHSHDYRSAEPLAGKSVVLLGAGLSGLDIAMELSNVNAKVILSHGQKPLTCPLPPGVQQAPPVTSVLDDGTLEFKDGKKANPEVFMFCTGYNFTFPFLDEKVGVKVQEHLVWPLYKFLIPPAYPSLFIVGICRAICPFPHFHIQSQFVLSVLDGSFRLPSREDMEKDIELDIAARRARGIATRHILKLDSEQWAYNDELAHLGGFKPLPRYWSNLYESNKVFRARDMLNYKTHNFTVLDNMEWKVHDVNGQQLQKPLAVNKQI
Protein: Interleukin 1-receptor accessory protein-like 2 (X-linked interleukin-1 receptor accessory protein-like 2 precursor (EC 3.2.2.6)) (B6ZK78)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MKLAGFMLFIINSAASINLKYISKRNSVDGCIDWSVDLKTYRVLAGEPLRVKCALFYSYIRTNYSVAQNAKLRLIWYRNKGDSEEPIIFSGHRLSKEGDSIWFRSAEMEDNGFYTCVLRNSTYCMKVSMSLTVEESEEGLCFSSRIRYQERAEITKSKMISCPDIDDYLAPYKQPIMTWYKECQRKEWRSSIIINTTSLWIPEVQEDDGGNYTCELKYGSKVVRRTTELKVTALLTTRPPKVLFPSERQASVIDVQLGMRLILDCKAFFGYSGDSKPIIYWMKGDKFVEELEGHIRESEVRVVREFLGEKEVELSLVFDAVEDTDMGNYTCNVENHIGRGSGSAILQKKDMYRLELVGGLGAIMLLLGIFTAIYKCYNVEIMLCYRQHFGSDEADDGNKEYDAYLSYTKVDLDSVEQEMSEEEQFALEILPDVLEKHYGYKLFIPHRDLIPSSTYIEDLARSVEQSRRLIIVLTPEFVARRGWSIFQFEPRLHSMLVTGEIKVIMIECPDLRSVINYQEVEDLKHTIRVLTLIKWQGPKSNQLKSKFWKQVRYEMPAKKKETMSRRQVLDSGEQGLFGDLQAVSTVAMTATSASLAPTQVEIPDYNEPSHMQMRHFCRSYEYELPTTAIATLNGRHMYCNLPMTLLNGRLTQNNIGKGKKEIHLNSSFVPLSGQELSSDIW
Protein: GTPase-activating protein BEM3 (Bud emergence protein 3) (P32873)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: GTPase-activating protein (GAP) for CDC42 and less efficiently for RHO1. Negative regulator of the pheromone-response pathway through the STE20 protein kinase.
Subcellular location: Cytoplasm.
Interaction partners:
- Cell division control protein 42
- Uncharacterized protein YMR124W
- Serine/threonine-protein kinase CLA4
- Bud emergence protein 1
- Cell division control protein 24
- Protein BNI1
- Rho-type GTPase-activating protein 1
- GTPase-activating protein BEM2/IPL2
- GTP-binding protein RHO1
- GTPase-interacting component 2
Sequence:
MTDNLTTTHGGSTTLELLAQYNDHRSKKDKSIEHIEKGTCSGKERNPSYDEIFTENIKLKLQVQEYETEIESLEKVIDMLQKNREASLEVVLEQVQNDSRDSYVNDQSFVLPPRSAERKAHIKSLNLPIPTLSPPLQQGSDVALETSVTPTVPQIGVTSNTSISRKHLQNMILNDEIEANSSFSSPKIINRSVSSPTKIHSEQLASPAASVTYTTSRITIKSPNKGSKSPLQERLRSPQNPNRMTAVINNHLHSPLKASTSNNLDELTESKSQQLTNDAIQKNDRVYSSITSSAYTTGTPTSAAKSPSSLLEVKEGENKALGFSPASKEKLDDFTQLLDSSFGEEDLVNTDSKDPLSIKSTINESLPPPPAPPTFFSPTSSGNIKNSTPLSSHLASPVILNKKDDNFGAQSAKNLKKPVLTSSLPNLSTKLSTTSQNASLPPNPPVESSSKQKQLGETASIHSTNTLNTFSSTPQGSLKTLRRPHASSVSTVKSVAQSLKSDIPLFVQPEDFGTIQIEVLSTLYRDNEDDLSILIAIIDRKSGKEMFKFSKSIHKVRELDVYMKSHVPDLPLPTLPDRQLFQTLSPTKVDTRKNILNQYYTSIFSVPEFPKNVGLKIAQFISTDTVMTPPMMDDNVKDGSLLLRRPKTLTGNSTWRVRYGILRDDVLQLFDKNQLTETIKLRQSSIELIPNLPEDRFGTRNGFLITEHKKSGLSTSTKYYICTETSKERELWLSAFSDYIDPSQSLSLSSSRNANDTDSASHLSAGTHHSKFGNATISATDTPSYVTDLTQEYNNNNNISNSSNNIANSDGIDSNPSSHSNFLASSSGNAEEEKDSRRAKMRSLFPFKKLTGPASAMNHIGITISNDSDSPTSPDSIIKSPSKKLMEVSSSSNSSTGPHVSTAIFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFLSFKRVVDENHNNPVQISLGFKELIESGLVPHANLSLMYALFELLVRINENSKFNKMNLRNLCIVFSPTLNIPISMLQPFITDFACIFQGGEPVKEEEREKVDIHIPQV
Protein: WRKY transcription factor WRKY28 (OsWRKY28) (Q0DAJ3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Modulates plant innate immunity against X.oryzae pv. oryzae (Xoo). Regulates negatively the basal defense responses to the compatible fungus M.oryzae.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223, ECO:0000269|PubMed:23462973}.
Interaction partners:
Sequence:
MAKMLPPPSQSVPSRPPSWLYIPPRRRHGTFTSSCAFRLSPSSPSSPPPPVLDFQYIQFMDSWIEQTSLSLDLNVGLPSTARRSSAPAAPIKVLVEENFLSFKKDHEVEALEAELRRASEENKKLTEMLRAVVAKYTELQGQVNDMMSAAAAAAVNAGNHQSSTSEGGSVSPSRKRIRSVDSLDDAAHHRKPSPPFVAAAAAAAYASPDQMECTSAAAAAAAKRVVREDCKPKVSKRFVHADPSDLSLVVKDGYQWRKYGQKVTKDNPCPRAYFRCSFAPACPVKKKVQRSADDNTVLVATYEGEHNHAQPPHHDAGSKTAAAAKHSQHQPPPSAAAAVVRQQQEQAAAAGPSTEVAARKNLAEQMAATLTRDPGFKAALVTALSGRILELSPTKN
Protein: Alpha/beta-Hydrolases superfamily protein (Q84JV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGNVTSNVAAKFAFFPPEPATYGVTKDDETGKLVFAGVSADKNVEVHQLTTKSGNKVVATFWRHPFARFTLLYSHGNAADLGQMVELFIELRAHLRVNIMSYDYSGYGASTGKPSEFNTYYDIEAVYSCLRSDYGIKQEEIILYGQSVGSGPTLHMASRLKRLRGVVLHSAILSGIRVLYPVKMTLWFDIFKNIDKIRHVNSQVLVIHGTNDEIVDLSHGKRLWELAKEKYDPLWVKGGGHCNLETYPEYIKHLKKFVNAMEKLSLTNPPPKQLTNEPSITETKHNRCLKFGKR
Protein: Solute carrier family 25 member 17 (F6RTR7)
Organism: Homo sapiens (Human)
Subcellular location: Peroxisome membrane {ECO:0000256|ARBA:ARBA00004585}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004585}.
Interaction partners:
Sequence:
MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH
Protein: ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24) (Q9GZR7)
Organism: Homo sapiens (Human)
Function: ATP-dependent RNA helicase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24204270}. Nucleus {ECO:0000269|PubMed:24204270}.
Interaction partners:
- ATP-dependent RNA helicase DDX18
- RNA-binding protein 28
- Probable ATP-dependent RNA helicase DDX56
- Nucleolar complex protein 3 homolog
- WD repeat-containing protein 74
- ATP-dependent RNA helicase DDX54
- Ribosome biogenesis protein WDR12
- Ribosome biogenesis protein BOP1
- Nucleolar complex protein 2 homolog
- Pumilio homolog 3
Sequence:
MKLKDTKSRPKQSSCGKFQTKGIKVVGKWKEVKIDPNMFADGQMDDLVCFEELTDYQLVSPAKNPSSLFSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEVKDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTWIPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPDDTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNENEEENLDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERRRQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKKTKKPKEPQPEQPQPSTSAN
Protein: Beta-amyrin 28-monooxygenase (EC 1.14.14.126) (Cytochrome P450 716A81) (BvCYP716A81) (A0A0U2U8U5)
Organism: Barbarea vulgaris (Yellow rocket) (Erysimum barbarea)
Function: Catalyzes the oxidation of the methyl group to a carboxyl group at the C-28 position of beta-amyrin to form oleanolate.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MYLTILFLFVSSILLSLMFLLRKHLSHFSYQNLPPGKTGFPLIGESLSFLSEGRQGRPEKFVTDRVRRFISSSTGVFKTHLFGYPTAVMTGASGNKFLFTNENKLVVSWWPDSVKKIFPYTQSTYTDESKKLRILLMQFMKPEALRKYIGVMDEVAQRHFETLWTNQKQLIVYPLSKKLTFSVACRLFLSMDDPERVSKLEDRFNSVVTGIYSVPIDLPGTRFNRSIKASRLLRKEVCAIIGQRREELKAGRASAEQDVLSHMLMSVGETKDEDLANYLIGILIGGHDTAAIATTFIINYLAEYPHVYQRVLQEQKEILKEKKEEERLKWEDIEKMKYSWNVACEVMRLVPPLTGNFREAIDHFTFKGFYIPKGWKLYWSATATHMNPDYFPEPERFEPNRFEGSGPKPYSYIPFGGGPRMCPGREFARLEILVIIHNLVNRFKWEKVFPNENKIVVDPLPKPGNGLPIRIFPHF
Protein: Medusa (C8V1R3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MSGYQRTPQAAVLDCDSAQSLQDGAAYSTYGQPVYMSTPLAPSPMTDHISQMSDCMPYMAKPEYASSYEDEKSPMITVEPCQLPEVTSYSPQRGSEGTRVFVQLQSPYDLHTTPYATLYIVFGSKKCECNPHFLGFRDSAFQYALSVDTPPFMSTGSPSLAVPLQLAMGGQNESPATTLQVGVYTYENAGQQSPSEDGRKRRISSFSADSTSRPIKRASTLPVQIKEEQSSYAAPYSPYLQPLPSMNGFAASYHTDSSPRMGATQYTTVSTNSQPSIRAPSPMAPSPMAPSWNSSFLSVNHDQRGSGYAVGRGVCQPKPSSPASFSNPTLIRTSTLQQSAGVVQTQSFNPYAMYPSKAVLKLNGDLNTMTHNWTREEQVAQRRLVQFTRMQSGSTIHADFKPVSPEERAPNSICISCIYWEGKDECFITSVDTIYLLESLVGVRFTVEEKNRIRRNLEGFRPLTVSKSKADSEEFFKVIMGFPAPKPRNIEKDVKVFPWKILGHALKKIIGKYSASYSSTAGALPTPIGSNYPSTGPASDSGAEGQSAASPQSISEGTPSSSYHQSNAVPIYSPPTETDGPIRTILPAVSQSYSNMTAPYSYTTVCHSGQVAPSGPAARSWELNQLATPSTMNGHPNPGNFNYMPPMTYSQSDYPQGH
Protein: At5g53620 (RNA polymerase II degradation factor) (Q93XY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At1g01170)
Sequence:
METAASSVATTRGGSLQNPSPTAPSRKEWRAVSDSQDTTDYVDLEQLKLNRTDERTIYENGREQDGYSNSEMLQQQILNVSRKKGELQQLEIELRAQMIARHEIMEIQSNYESQFTEYANAAARMQEQLHENERSIREAERKLEEKDRELHAIKLDNEAAWAKEGILREQNKELATFRRERDHSEAERSQNIHKISELQEHIQEKESQLSELQEQNRIAQETILYKDEQLREAQGWIARAQEIDALQSSTNHSLQAELRERTEQYNQLWHGCQRQFAEMERLHVHTVQQLQQELANVREAGGSKTNSGGASQTIQNSGNQFDAHGNSAESANISVHSNGKSADNISSFTSTDDKATQNNRVDGISASNLATHGFLQAGQMTPLHSFVMHQQEISQLVQPQVPSQHIEQSVLLQQKAQAVPDSSQMPMQNHVHPSQGVHGLVQSFGQGYGDIQTSQVAQYGTTTTPSSVNEQAVESGNGDYNGSNQSENNFQDISSQFRDALRLDSHSQNQKPEELNGQVSPDEHSGAKSIVPETLVSSGKPERNSECALLDERSLLTCILRTIPAGGRIRISSTLPNRLGKMLAPLHWHDYRKKYGKLDDFVASHLELFSIEDDYIQVRDGAQKMVAASAAAAKVAAAAAASSSPNSIYVAMTPMAQSQGLKKNDNRVRQSSDFMVKQQRKL
Protein: Vacuolar transporter chaperone complex subunit 4 (Polyphosphate kinase) (SPX-dependent polyphosphate polymerase VTC subunit 4) (Vacuolar membrane polyphosphate polymerase catalytic subunit) (PolyP polymerase) (EC 2.7.4.1) (P78810)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalytic subunit of the vacuolar transporter chaperone (VTC) complex. The VTC complex acts as vacuolar polyphosphate polymerase that catalyzes the synthesis of inorganic polyphosphate (polyP) via transfer of phosphate from ATP to a growing polyP chain, releasing ADP. VTC exposes its catalytic domain vtc4 to the cytosol, where the growing polyP chain winds through a tunnel-shaped pocket, integrating cytoplasmic polymer synthesis with polyP membrane translocation. The VTC complex carries 9 vacuolar transmembrane domains, which are likely to constitute the translocation channel into the organelle lumen. PolyP synthesis is tightly coupled to its transport into the vacuole lumen, in order to avoid otherwise toxic intermediates in the cytosol, and it depends on the proton gradient across the membrane, formed by V-ATPase. The VTC complex also plays a role in vacuolar membrane fusion.
Subcellular location: Vacuole membrane {ECO:0000250|UniProtKB:P47075}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Vacuolar transporter chaperone complex subunit 2
- Glycerophosphocholine phosphodiesterase gde1
- DNA replication licensing factor mcm4
- Vacuolar transporter chaperone complex subunit 1
- Large ribosomal subunit protein eL34B
- T-complex protein 1 subunit alpha
- Probable T-complex protein 1 subunit eta
- T-complex protein 1 subunit zeta
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit gamma
Sequence:
MKFGQLLKETLMYEYKYSYVNYDKLKKEIKRRNDQGGWSEEDESDFVELLEKELDKVYSFQKNKSAEVMERIRFCEEQTDEVVRRLDSDNPPNENDFAILETELTDIMATVHDLAKFSELNYTAFYKIIKKHDKHTGWILKPVFAARLNAKPFFKEQYDLLVVKLSKLYDFVRTRGSPIKGDSAAGGTQQNFVRQTTKYWVHPNNVTELKIYILKHLPVLVFNPNKEFAREDAAITSIYYDNDDLDFYLGRLEKREGAEAIRLRWYGNMDNNNIFVERKTHREDWTGEKSVKARFPLKEKYVNAFLRGDYTVEEAFAKMRKDGKKSLKEIESLERLAKEVQYTVLSRGMKPYVRSFYERTAFQLPGDARVRISLDTNLSLIREDGPSRAGNNWRRMDIGIDYPFDQLPDEDIVRFPYAILEVKLQTQFGQDPPEWVNNLVNSHLVEAVPKFSKFIHGVSTLFYDRVTLLPYWFPQMDIDIRKPATHTFIQGRSQSGTHSSSVSANVLTDSENTPIHADGDNYVDEESRIGSSSTRNDNSTFQTSDSFQELDERTNLLDISKRKGRDSFVAALNSRLKDIKDSFFLETVPKFEEPTEPTVIYEQKYVSPPGKRIYVPVRVEPKTYFALERTYLDYLRYSILMGSIGITLFSFAKTRSGILGAASFTLVALFAIFYSTFLYLWRAVNIAKHNAVRYDDRFGPTAICVITFAAISANVILNFNA
Protein: Zinc finger protein ZIC 4 (Zinc finger protein of the cerebellum 4) (Q8N9L1)
Organism: Homo sapiens (Human)
Function: Binds to DNA.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Zinc finger protein ZIC 1
- Paraneoplastic antigen Ma2
- Amphiphysin
- Delta and Notch-like epidermal growth factor-related receptor
- Leucine-rich glioma-inactivated protein 1
- Dihydropyrimidinase-related protein 5
- Recoverin
- Transcription factor SOX-1
- Forkhead box protein L2
- Glutamate decarboxylase 2
Sequence:
MRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQLTAASSPSVFPGLHEEPPQASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSLCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVHGRSPPPSSGYDSATPSALVSPSSDCGHKSQVASSAAVAARTADLSE
Protein: GRIP and coiled-coil domain containing 88 kDa (LD02947p) (Q9VGR1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
- Bystin
- Protein Aatf
- Pre-rRNA-processing protein TSR1 homolog
- HEAT repeat-containing protein 1 homolog
- LD10780p
- RNA-binding protein NOB1
- FI08810p
- FI04457p
- Probable RNA 3'-terminal phosphate cyclase-like protein
- LD47749p
Sequence:
MEKRQRELEALVSTQKEQLGRYEKRLKDVVTAYKGLLKEKEALETSLAAHAEATAVGESGSPARELESKKTSTDSADGATEGAAPGPPAPPAEGQLQTQIITLMNSLATLSAEKSRMEASFQADKKQLRSQIAQKEQTIQELNTRAKEQAARAKSDVDEIKAKWIVERQEREKETNNQMLMIRELQKLYADERHLKDNIEMQLNNFKTQFASNEAENSRLRELQSQLKEARSQLKQFQAKTEHSAAASASADSAALLQQVRLEMQQLKEQHAVAIRQEQRRVLRAEEQSRRQAALHEDRVASLEARLAELSTTVGSYDRLRQQDQDSIHDLKQQLQDLEQAHVRPTSNSRALNEDVDVATLVDEMVRLKKLLTTANARSANPLDLGEILSFSGQTATRVESHAHCEQQLQGVQQMLEASKQQRQLLEQKVQLQHSHIQTLQEKVQVLNRNIDEAEVELKQQGEKLRLALKNERTKWQEAKAELENETRCKLNELEQLLQKQRQRSLQLLDEKEQEIKTLQTSFEVFHSASGVGSTLATPTLEAAADSFHYSSDTDSVEGEQRERKLKVRSKKMSMGENCHMLHYANELARKDIEITTLRKAKYAAESTLRKAIQDKVTSQQEMHEKIECLKEQVDRLERCKTREGANLEYLKNVIISYIVTRDADGKRHMLNAISAVLQFTAAEMQAINASFQKK
Protein: protein-synthesizing GTPase (EC 3.6.5.3) (O64490)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Eukaryotic translation initiation factor 2 subunit beta
- Eukaryotic translation initiation factor 2 subunit alpha homolog
- Eukaryotic translation initiation factor 2 subunit alpha
- Eukaryotic translation initiation factor 2 subunit beta
- Eukaryotic translation initiation factor 3 subunit A
- Eukaryotic translation initiation factor 2 subunit beta
- Eukaryotic translation initiation factor 3 subunit E
- Translation initiation factor eIF2B subunit beta
- Translation initiation factor eIF2B subunit gamma
- Eukaryotic translation initiation factor 3 subunit C
Sequence:
MSRNKGLAEQDLKKLDVTVLHPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLGYANAKIYKCEDEKCPRPMCYKAYGSGKEDTPNCDVPGFENSKMKLLRHVSFVDCPGHDILMATMLNGAAIMDGALLLIAANETCPQPQTSEHLAAVEIMQLKHIIILQNKIDLIQENVAINQHEAIQKFIMNTVADAAPIVPVSAQLKYNIDVVCEYIVKKIPIPERNFVSPPNMIVIRSFDVNKPGYEVDEIKGGVAGGSILRGVLRVNQLIEIRPGIVTKDERGNSKCTPIYSRIISLYAEQNELQFAVPGGLIGVGTTMDPTLTRADRLVGQVLGEIGSLPDVFVELEVNFFLLRRLLGVRTKGSEKQGKVSKLTKGEILMLNIGSMSTGAKVVGVKVDLAKLQLTAPVCTSKGEKVALSRRVEKHWRLIGWGQIQAGTTIEVPPSPF
Protein: Accumulates dyads protein 4 (Q05955)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. May be required to stabilize the outer plaque of the spindle pole body (SPB).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:12796288}. Note=Localizes to the meiotic outer plaque of the SPB, at the end of the meiotic spindles.
Interaction partners:
- Sporulation-specific protein 21
- Sporulation-specific protein 74
- Meiotic plaque component protein 54
Sequence:
MNKDVDYQTFKKSLRKEFKKAVKTILNLQAYNGDLIRDFLALYIPYHVVFYNLSIMKKGSPLRIQTNNLLKEALAKILNFNLAMGPKHIIKIMKKDKADPETMNKLKLVLYIKLFQGVFGHVDKNYNLAFQSFRWCLQFIAYSKRTRLFASIADEQIGAFYELCELFISMLCCHCFLIDLKENEALVGNNLKNFIKRQNPNYSHGFDLNEETKSLQWHWSLDEVDVIEALYCVAFDAMDKITLKFSKVNENFVFSQFFQYCAEIEEMLAILRGKIWECECDVFGPRIGLLVDSNHMNETIQKNILSITFKLKNDPQIICCLNKILEGLLLSSGVQFKVIQFFYVLKLYYMQDNEYTFEASSEMDKLTIECLCIIENIIDACDNPDEVTDYQLPKVLLTAMEGKLLVAEKISEDNDCSESLDDYHPRTYQFRHPRIIIDKMKTKLKQKLRFDSPKDPETDDHWIEYWKYCYQDNIGNLPDILSRIYQTFTDPSN
Protein: Dynamin associated protein isoform Dap160-2 (O61639)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNSAVDAWAVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLLSSLTGDVPSMTPRGSTSSLSPLDPLKGIVPAVAPVVPVVAPPVAVATVISPPGVSVPSGPTPPTSNPPSRHTSISERAPSIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKIKSRPGSVSGVVSRPGSQPASRHASVSSQSGVGVVDADPTAGLPGQTSFEDKRKENYVKGQAELDRRRKIMEDQQRKEREERERKEREEADKREKARLEAERKQQEELERQLQRQREIEMEKEEQRKRELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMSELKAELSALITKCEDLYKEYDVQRTSVLELKYNRKNETSVSSAWDTGSSSAWEETGTTVTDPYAVASNDISALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILVPLEQNAEPGWLAGEINGHTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVADTYNDNINTSSIPAASADLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTIGSRTGMFPSNYVQKADVGTASTAAAEPVESLDQGMRAKRSEIAQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYVKVLQGGRNSGRNTPVSGSRIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGELNGLSGLFPSNYVGPFVTSGKPAKANGTTKK
Protein: Holliday junction resolvase MOC1, chloroplastic (EC 3.1.21.10) (Protein MONOKARYOTIC CHLOROPLAST 1) (AtMOC1) (Q8GWA2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Mediates chloroplast nucleoid segregation during chloroplast division.
Subcellular location: Plastid, chloroplast stroma, chloroplast nucleoid {ECO:0000269|PubMed:28495749}.
Interaction partners:
- tRNA-specific adenosine deaminase TAD1
- Protein PAT1 homolog
- Transcription termination factor MTERF4, chloroplastic
- Transcription termination factor MTEF1, chloroplastic
- Scarecrow-like protein 21
- Scarecrow-like protein 13
- Scarecrow-like protein 3
- Transcription termination factor MTERF9, chloroplastic
- Scarecrow-like protein 4
- Transcription termination factor MTEF18, mitochondrial
Sequence:
MATTVYGQASLPQMHSLFSKVRPFLSHSPSFTAPFTRRRSFPFSALPTTKAIDAALMKEKWLDSLSLTSQDEDTTPENAESSCIIGIDPDLSGALALLKFDHLGSSSFAQVYDTPHIPVLVGKRVRKRLDAKSIVQLIQSLDVPSGSRVYIEQSNPFPKDGKQGWYSGGFGYGLWIGTLVASGFCVIPVSASLWKRHFQLASGSCTKDDSRRVAAELFPSLSSQLKRKKDHGRAEALLIAAYGEALKTEKLLIQPKELLSQVNYLENQLVEVK
Protein: AFLJ (Nonfunctional aflatoxin co-regulatory protein) (Possible transcriptional modulator) (Q8J2U9)
Organism: Aspergillus oryzae (Yellow koji mold)
Interaction partners:
Sequence:
MTLTDLEICAEEIATAARTLASDGHSGGYSAGLPDHLRPVQRTLIANASQVLALASQPADLVRQLALYNQLLACLRWLGEFQVLACIPLDESVPFEDVADIAGVPECRLRRLVRPLFTIGFLCEPSPGHVAHSVLSKQFVTQPALLDAILFMSETLAPSASAMGTQTRRFGASEQAEDSAWNMAVGSDSPFAACLQQRPKVKRQLGAYLSYVSSSIDAGVEDTLTRMNWQNLGMATVVHVGAQSPSLVVALAPQFPSLRFLVQTEAKTESGGHQPCLDNHGISALKLASIPLHLRARITWGTRLSTATQPVLDAAVYLISIPFPSPQSPAMEITMRVAQALKAHVEVLRNNSDERLILTLPMSSATRSMDAAARAAVSLSDLSLLQLTNGGSLNMGEIRDLLRSRSDGLVVMREVRSPTNAVIAFEIQYRVDNDDNRY
Protein: Dynactin subunit 2 (Q6AYH5)
Organism: Rattus norvegicus (Rat)
Function: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. In the dynactin soulder domain, binds the ACTR1A filament and acts as a molecular ruler to determine the length (By similarity). Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q13561}. Membrane {ECO:0000250|UniProtKB:Q13561}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q13561}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0A5G2QD80}.
Interaction partners:
- Dynactin subunit 4
- Dynactin subunit 1
- Alpha-centractin
- Dynactin subunit 6
- Actin-related protein 10
- Dynactin subunit 5
- Dynactin subunit 3
- Beta-centractin
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic dynein 1 heavy chain 1
Sequence:
MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELSSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGDYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVVLAKQLAALKQQLVASHLEKLLGPDAAINLADPDGALAKRLLLQLEATKSSKGSSGGKSTGGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELEATVRCDQDAQNPLSAGLQGACLMETVELLQAKVNALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQNKVHQLYETIQRWSPVASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMMASSLKDNTALLTQVQTTMRENLATVEGNFASIDARMKKLGK
Protein: Kunitz-type serine protease inhibitor LmKTT-1a (Delta-KTx 2.1) (SdPII) (P0DJ46)
Organism: Lychas mucronatus (Chinese swimming scorpion)
Function: Dual-function toxin that completely inhibits trypsin activity at a molar ratio of 1:1 (Ki=140 nM) and that inhibits mKv1.3/KCNA3 potassium channel currents (1 uM inhibits 50% of currents) (IC(50)=1.58 uM). Shows also weak inhibition on Kv1.1/KCNA1 (1 uM inhibits 25% of currents) and Kv1.2/KCNA2 (1 uM inhibits 25% of currents).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MKSFLLIALVLFFLFVSYASAKKKCQLPSDVGKGKASFTRYYYNEESGKCETFIYGGVGGNSNNFLTKEDCCRECAQGSC