wanglab/gogpt-training-data huggingface dataset:
Protein: palmitoyl-protein hydrolase (EC 3.1.2.22) (M9PEW1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- LD22655p
- Neuropathy target esterase sws
- palmitoyl-protein hydrolase
- LD30288p
- Igloo, isoform A
- Ras-like protein 1
- Nitric oxide synthase
- Matrix metalloproteinase 1, isoform C
- Trafficking protein particle complex subunit 5
- Palmitoyl-protein thioesterase 1
Sequence:
MAAPVIVEATVKQTATLIFMHGLGDTGHGWSSALAAIRPPFMKVICPTAPTQPVSLNAGFRMPSWFDLKTLDIGGPEDEPGIQSARDSVHGMIQKEISAGIPANRIVLGGFSQGGALALYSALTYDQPLAGVVALSCWLPLHKQFPGAKVNSDDVPIFQAHGDYDPVVPYKFGQLSASLLKSFMKNVTFKTYSGLSHSSSDDEMDDVKDIISKWTQWDSQNMARKAQCCQLS
Protein: Uncharacterized endoplasmic reticulum membrane protein YJR015W (P47090)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Putative uncharacterized protein YDR133C
Sequence:
MTSSLDDIEPTAYNNMEADEEYCRRNDIHDLSSVVGDAVSQGVPDMDGQTTDSSKDPEPNSEDKKAFPPSSGSFFSPNLQGQRKKVLLKFVFTNCLLAIICFTMFVLFWGALYDTSKYLHKVKLLVVIQEPPVVILDNNSSMVVPSISYALPTFINKIPCDWDIYNSPTFQAKFDVNTPQQVNDKVVDLVYDEKYWFAINIKPNATETLFESLINDTAPLFNSTLFNQVVYETGRDPTNLKSTILPVAQTIEEYYHTFYTLNYLPPLLTNITQVYRYALTNNARYIAAAGKYNYEYYDHRPFTDRILLAPTQIGVVYCLLLTFFQFLLYGPLHVEMAKVLRPANGLIYRIAMSWFTFFFASLFFCTTTAIFQVDFTKSFGRGGFVVYWMSTWLFMLAAGGANENAVMLVITLGPQYLGFWILSFVILNIAPSFFPLALNNNVYRYGYMMPVHNVIDIYRVIFFDVTRRKMGRNYGILVALIALNTALLPFVGKYASRKLKQKALVAAKQS
Protein: Nuclear polyadenylated RNA-binding protein 3 (P38996)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be required for packaging pre-mRNAs into ribonucleoprotein structures amenable to efficient nuclear RNA processing. Binds to poly(A)+ RNA. Appears to act in the maintenance of CLN3 mRNA levels.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:7962083}.
Interaction partners:
- Protein NRD1
- Helicase SEN1
- Protein AIR2
- Exosome complex exonuclease RRP6
- Nuclear cap-binding protein subunit 2
- Nuclear cap-binding protein complex subunit 1
- ATP-dependent RNA helicase DOB1
- DNA-directed RNA polymerase II subunit RPB1
- Protein AIR1
- Protein PCF11
Sequence:
MSDENHNSDVQDIPSPELSVDSNSNENELMNNSSADDGIEFDAPEEEREAEREEENEEQHELEDVNDEEEEDKEEKGEENGEVINTEEEEEEEHQQKGGNDDDDDDNEEEEEEEEDDDDDDDDDDDDEEEEEEEEEEGNDNSSVGSDSAAEDGEDEEDKKDKTKDKEVELRRETLEKEQKDVDEAIKKITREENDNTHFPTNMENVNYDLLQKQVKYIMDSNMLNLPQFQHLPQEEKMSAILAMLNSNSDTALSVPPHDSTISTTASASATSGARSNDQRKPPLSDAQRRMRFPRADLSKPITEEEHDRYAAYLHGENKITEMHNIPPKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKNAFGFIQFDNPQSVRDAIECESQEMNFGKKLILEVSSSNARPQFDHGDHGTNSSSTFISSAKRPFQTESGDMYNDDNGAGYKKSRRHTVSCNIFVKRTADRTYAIEVFNRFRDGTGLETDMIFLKPRMELGKLINDAAYNGVWGVVLVNKTHNVDVQTFYKGSQGETKFDEYISISADDAVAIFNNIKNNRNNSRPTDYRAMSHQQNIYGAPPLPVPNGPAVGPPPQTNYYQGYSMPPPQQQQQQPYGNYGMPPPSHDQGYGSQPPIPMNQSYGRYQTSIPPPPPQQQIPQGYGRYQAGPPPQPPSQTPMDQQQLLSAIQNLPPNVVSNLLSMAQQQQQQPHAQQQLVGLIQSMQGQAPQQQQQQLGGYSSMNSSSPPPMSTNYNGQNISAKPSAPPMSHQPPPPQQQQQQQQQQQQQQQQPAGNNVQSLLDSLAKLQK
Protein: Probable eukaryotic initiation factor 4A (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (Q388E8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- PRP1 splicing factor N-terminal domain-containing protein
- U5 small nuclear ribonucleoprotein component, putative
- Cell division control protein, putative
- Uncharacterized protein
- Protein arginine N-methyltransferase 7
- ATP synthase alpha chain
- ATP synthase subunit beta
- ATP synthase F1 subunit gamma protein, putative
Sequence:
MLTVCPLSFFTRALLVCFKSLTRLSPPCAPILPLTKKKRYLKMHGMNFGQGGHQQFNPNANPWARAPAFGEAGHQVGYNNYGGYQQRPREGFDGPSRGRGEFIRRNVPYQGETSGHGYHREEPADEDIFKDHTPGINFDQHGEVNMTITPNDIAPVLSFSEMNMVPVLLENVKRCGYTKPTPVQSLGIPTALNHRDLMACAQTGSGKTASYLIPAINEILLNISNRPPYSPGSHSSPQALILAPTRELSLQIYGEARKFTYHTPVRCVVVYGGADPRHQVHELSRGCKLLVATPGRLMDMFSRGYVRFSEIRFLILDEADRMLDMGFEPQIRMIVQGPDSDMPRAGQRQTLLYSATFPVEIQRLAREFMCRHSFLQVGRVGSTTENITQDVRWIEDPDKRQALLTLLRENEGKLVLVFVEKKRDADYLERFLRNSELACVSIHGDRVQREREEALRLFKSGACQVLVATDVASRGLDIPNVGVVIQYDMPSNIDDYVHRIGRTGRAGKVGVAISFFNEKNRNIVDDLIPLLNETNQVISPEVRALAKRPNNNNNNNNRGGGGGGYRGFGRGGNSGGFGMGGGRGGGGGGGGYRGGRGGNSGGFGMSNVFGRGGNSGGFGMGGGRGGGGGGGGGGFGSGGFGASGGNMRGMFGGGGGGPTM
Protein: Periphilin 1 (F8W0Q9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLRHPVRSLVQVAYRRDEMWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF
Protein: Putative invertase (EC 3.2.1.26) (Beta-fructofuranosidase) (Saccharase) (O42878)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Hexokinase-1
- Hexokinase-2
- Alpha-galactosidase mel1
- Putative beta-glucosidase
- Alpha-glucosidase
- Invertase
- Alpha-glucosidase
- Uncharacterized family 31 glucosidase C1039.11c
- Uncharacterized family 31 glucosidase C30D11.01c
- Glucan 1,3-beta-glucosidase 2
Sequence:
MPVRPCIHFTPPEGFMNDPNGLVYSNGKWHLFFQWNPTGNQAGNQHWGHAVSKNLYKWKLLPTALAPGDDHGLMFSGSAVIDKTNSSGFFESGFFSRKSVDPEERIVLIYTTHYDNRETQNIAYSLDGGITFIKYKKNPILDIKESQFRDPKVFWHEESRAWIMVVVLAQKYKVLFYHSLNLRDWVKLSEFGSAGVLGYQYECPDFVRLPIEGTDEFRWVLIVSINPGSSINGGSMVQYFIGDFDGQTFTPIDSASRILDCGHDCYATQTFGNAPDGRVISISWASNWNYTNDVPMRMKHRGMFTIPRELTLCYTHLNQETRGLVLRQRPVNLHHLYYPDSLPAPLLLNRVCEFPTVWTSATVFYLAVSIPKSIVLESPMEFLCLTWSTTPDVETSKEYFELGYRFHDGAVYVERGVCSSSWKYPLYPERCTSSVPPSSYEDNYILEIEAVVDHSIIEVYLQGGIMCLTNAYYFKGDEPLQYYYLRVPTGASLAKSGMQPLLNNRPHS
Protein: Fibronectin type-III domain-containing protein (Q8BUA2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLSSLGCLLLCGSIALALGNAQKLPKGKKPSLKVHTNTTSDSILLKFLRPNANVKLEGFLLGYGSNVSPNQYFPLPTEGKFTEAVVDAEPKYLIVVRPAPPPSQKKSCSGKSRPRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPSDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPNTVYEFGVKDNIEGGIWSKIFNHKTIVGSKNKVNGKIQSTYDQVHSVPVPRKLIPLTIIKQVIQNVTHRASTKSPDKTPFGGTILVHLIIPGLNESTVKLPTSIMLEISDALKAQLAKNETLALPAESKTPEVEKLAGQPVTVTPESVSRSTKPTLSSALDTAETALAPKRFPEFPEAKTAFPLEKPRGSWASSEEPWVVPGAKTSEDSRVVQPQTATYDVISSSTTSDETEIEIHTATRDPILDSVPPKTSRTAEQPRATLAPIEALFESRNVEIFTSPEVRPTTAAPQQTTSIPSTPKRQSTPKPPRVKPAPEPETRPSAQTTKGSTQDQKTRSPPPPPS
Protein: HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) (Q9BT25)
Organism: Homo sapiens (Human)
Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Subcellular location: Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000305|PubMed:19369198}. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively. Localizes to mitotic spindle microtubules. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}.
Interaction partners:
- HAUS augmin-like complex subunit 3
- HAUS augmin-like complex subunit 1
- HAUS augmin-like complex subunit 2
- HAUS augmin-like complex subunit 6
- HAUS augmin-like complex subunit 7
- HAUS augmin-like complex subunit 5
- HAUS augmin-like complex subunit 4
- Tubulin gamma-1 chain
- Kinetochore protein NDC80 homolog
- Protein NEDD1
Sequence:
MADSSGRGAGKPATGPTNSSSAKKKDKRVQGGRVIESRYLQYEKKTTQKAPAGDGSQTRGKMSEGGRKSSLLQKSKADSSGVGKGDLQSTLLEGHGTAPPDLDLSAINDKSIVKKTPQLAKTISKKPESTSFSAPRKKSPDLSEAMEMMESQTLLLTLLSVKMENNLAEFERRAEKNLLIMCKEKEKLQKKAHELKRRLLLSQRKRELADVLDAQIEMLSPFEAVATRFKEQYRTFATALDTTRHELPVRSIHLEGDGQQLLDALQHELVTTQRLLGELDVGDSEENVQVLDLLSELKDVTAKKDLELRRSFAQVLELSAEASKEAALANQEVWEETQGMAPPSRWYFNQDSACRESGGAPKNTPLSEDDNPGASSAPAQATFISPSEDFSSSSQAEVPPSLSRSGRDLS
Protein: Sperm flagellar protein 1 (Calponin-homology and microtubule-associated protein) (Q99JL1)
Organism: Mus musculus (Mouse)
Function: Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock. Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Essential for ciliary central apparatus formation which requires both its microtubule-binding and bundling activities and for ciliary localization of HYDIN and SPAG6 in ependymal cilia. Binds actin in intestinal epithelial cells (IECs), essential for IECs survival and contributes to formation of filopodia and lamellipodia in migrating IECs (By similarity). Regulates planar cell polarity signaling pathway and asymmetric microtubule accumulation in ciliated epithelia (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15979255}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:15979255}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:30535028}. Apical cell membrane {ECO:0000250|UniProtKB:Q0IH24}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q9Y4P9}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:Q9Y4P9}. Cell projection, microvillus {ECO:0000250|UniProtKB:Q9Y4P9}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q9Y4P9}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q9Y4P9}. Note=Also found at the apical tip of cilia (PubMed:30535028). Present in the tails of developing and epididymal sperm, internal to the fibrous sheath and around the outer dense fibers of the sperm flagellum (PubMed:15979255). Colocalizes with TJP1 and CGN at sites of cell-cell contact in intestinal epithelial cells (By similarity). {ECO:0000250|UniProtKB:Q9Y4P9, ECO:0000269|PubMed:15979255, ECO:0000269|PubMed:30535028}.
Interaction partners:
Sequence:
MESSVDEEALHQLYLWVDNIPLSRPKRNLSRDFSDGVLVAELIKFYFPKMVEMHNYVPANSLQQKLSNWGHLNRKVLNKLNFSVPDDVMRKIAQCSPGVVELVLIPLRQRLEERQRRQKLGVGSLQELAPQDSSGYMDMGLPQKVRGEGAPALGEQLREGRPLASRPPGYNQALQGDPSFVLQIAEKEQELLASQETVQVLQMKVKRLEHLLQLKNVRIDDLSRRLQQAERKQR
Protein: AAA family ATPase (A0A1D8PND0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- mRNA-binding ribosome biosynthesis protein
- Sgd1p
- ATP-dependent RNA helicase
- ATP-dependent RNA helicase DBP9
- Nucleolar GTP-binding protein 1
- Ribosome biogenesis protein ERB1
- RNA-binding GTPase
- Ribosome biogenesis protein NSA1
- Ribosome biogenesis protein YTM1
- Nucleolar complex-associated protein 3
Sequence:
MSKSRTVTGSLDQKIYNLIHDLLQEQTEENKRAATADEEHDPFSCMASSHNLTVSQVLAYVQMKDFQLKRMKKNYLEKSIAASLKVIRQDETEEFGDRENGIGDESEAENDRECENDLMEVKDSNAINKSVVSLWNQEKTDGESDGVNNEEGQQADTTELLKGNKRKAKGSAKTQLKKQKRKIDYSTPNIDLSSLGGVESVTTQLLEIIGLPILHPEIYSSTGVEPPRGVLLYGPPGCGKTTIANALAGELKVPFINISAPSVVSGMSGESEKKLREIFEEAKQIAPCLIFMDEIDAITPKRDGGAQREMEKRIVAQLLTLMDELTLEKTGGKPVVVIGATNRPDSLDSALRRAGRFDREICLNVPNEEQRISILKAMTKNIKLENGEHFNYRELSKLTPGYVGADLKSLVTAAGISAIKRIFETMSELQEESHSVKDDSMDVDPVSLDANKEDMIKKFEQKSEAEKLSTIKKFLNMHPDPLNQEQLAPLAITYQDFVNALPSVQPSAKREGFATIPDVTWQNVGALFKIRMELHMCIVQPIKKPELYLKVGIAAPAGVLMWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESEKAVRQVFQRARASTPCIIFFDELDALVPRRDTSMSESSSRVVNTLLTELDGLNDRKGVFVIGATNRPDMIDPAMLRPGRLDKTLYIELPTPEERLEILKTLVRTNNSPLHRNVDLNAISRDPRCGNFSGADLSSLVKEAGVWALKKRFFQNQKIQELDSSGFYEDSIGEDDISITAEDFDHALSSIRPSVSDRDRMRYEKLNKKLGWNIISDKEPDDAGSTSDKND
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-B (Q8LGE7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}. Mitochondrion intermembrane space {ECO:0000250}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 6
- Transmembrane protein
- NADH dehydrogenase 1 beta subcomplex subunit 10-B
- NADH dehydrogenase iron-sulfur protein 8-B, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase iron-sulfur protein 8-A, mitochondrial
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase 1 alpha subcomplex subunit 13-B
Sequence:
MSSAVDATGNPIPTSAVLTASAKHIGMRCMPENVAFLKCKKNDPNPEKCLDKGRDVTRCVLGLLKDLHQKCQKEMDDYVGCMYYYTNEFDLCRKEQEAFEKVCPLK
Protein: ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 13) (H2L0N8)
Organism: Caenorhabditis elegans
Function: Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. Required for normal sensory cilium function. May act by maintaining the association between IFT subcomplexes A and B.
Subcellular location: Cell projection, cilium membrane {ECO:0000269|PubMed:20231383, ECO:0000269|PubMed:20530210, ECO:0000269|PubMed:24339792, ECO:0000269|PubMed:31259686}; Lipid-anchor {ECO:0000269|PubMed:20231383, ECO:0000269|PubMed:20530210, ECO:0000269|PubMed:24339792}. Note=Associates to the cilium membrane via palmitoylation. Localizes to proximal ciliary membranes, to an inversin-like subciliary membrane compartment, excluding the transition zone.
Interaction partners:
- Protein unc-119
- Protein XRP2
- Cilia- and flagella-associated protein 36
- Intraflagellar transport protein 88 homolog
- Cytoplasmic dynein 2 light intermediate chain 1
- Phosphodiesterase delta-like protein
- Protein kinase domain-containing protein
- B9 domain-containing protein 1
- Intraflagellar transport protein che-13
- WD_REPEATS_REGION domain-containing protein
Sequence:
MTEKSWFETIFCCCCHRTPIIRREIKLGCFGIGSAGKTTFLKVLKGEDPRDLLRTNGFSTVKMEYDETFHLTIYDVGGDKGIRGIWSNYYAEVHGIIYVIDYSTDETFTESIEALHSLTSNPHVQKKPIFLLLNNQNNREFDDVEISNETKIQAGQHKIVLFSHFNKYNGYLDNIKSATLTVMARAKKDRNEYQEQFVRFIDSISEHYVELSEGVKTAELALRIRQEEAKEQRRLMQMKVEHDALKADVAGLELRNQPPVQPPIPPDPPSDPKSASVHIEESPPMSLASSTIPSDIIQSTPETGTPRDPVNFCRISQTSTKPVSPESNSVKEEPTIILKDNYFLPPKAPGRQYSRIQRIQNVLNNRVVPK
Protein: Spermathreecae, isoform F (EC 3.1.3.-) (Q0KI33)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEVFQTDSHYIFVKRDKSLWWHRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPNVYEPHLVVVKEASAVGVLYPPHLVYKIKSICILSADDPDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKNTTQQAANLATKQVKSSVGIREPRHIERRITEELHKIFDETDSFYFSFDCDITNNLQRHEAKSEESQSQPDERFFWNKHMIRDLINLNDKTWILPIIQGFMQVENCVIGNECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRHHQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQSGKEKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRFFIQNFADSFRQCIIDLMQGQLLRAEDLQEDEVLSTILQILTPETRPPLHGYYNPGVLGPELQLLESIVTTSYYLARFKDSYRQATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLVEDCRRLLLGTAQYPVGAWGLIDADPSSGDINETEVDTILLLTDDCYIVAEYDSHLDKIVRFEKVQLTQVRLIELGMHQQTKIFQGSAPAHLCLRLNYSVDEQEGYFHMFRSANLRFFNNMAYVIKTQEEVAESMTSIVEMFRIALDNAGNTEVRYITGGVLQRRKSKLPTLDVPRGMPRNLSESQLVQLSSKALSNMAGQFSKLGQTFKKPQAHPSSLAATMNPQVMRQRDSEIESGQEAEKAVFTLGRKHRNSNSASSTDTDEHDNSLYEPEVDSDVEIAMDKSNYNENAFLPSVGIVMGNQKEDSPSSSDEIRHLEQKDSMCKTTEDVLTISITSVTDHVGLPTGLLENAPAIRPITPNPLICVEAHEAFDDREEGVKPVSSTSARDLSLPGLPTHPEANKLKQLTSPLSKLAKNIGLNLDPRKIATKTGVLSPTILSAENSPPERDPSSRDHLLELWEAEKCKTKLIAL
Protein: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.33) (EC 1.14.11.54) (Alkylated DNA repair protein alkB homolog 3) (mAbh3) (Q8K1E6)
Organism: Mus musculus (Mouse)
Function: Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A) (By similarity). Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Can repair exocyclic 3,N4-ethenocytosine adducs in single-stranded DNA. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons. Requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96Q83}. Cytoplasm {ECO:0000250|UniProtKB:Q96Q83}. Note=Colocalizes with ASCC2 and ASCC3 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage. Predominantly localizes to the nucleus. {ECO:0000250|UniProtKB:Q96Q83}.
Interaction partners:
- Nucleic acid dioxygenase ALKBH1
Sequence:
MEDKRQRARVQGGWATPTKSQSATQPASPARSRLSQTAGPAWRSKEQQQCDRQFVFKEPQLVVRAAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILEQLCKDVPWKQRMGIREDVTYPQPRLTAWYGELPYTYSRITMEPNPHWLPVLWTLKSRIEENTSHTFNSLLCNFYRDEKDSVDWHSDDEPSLGSCPVIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSRQPRVNLTFRTVYPDPRGAPR
Protein: Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) (Q4Q8P6)
Organism: Leishmania major
Interaction partners:
- glycerol kinase
- Glycerol-3-phosphate dehydrogenase [NAD
- Dihydroxyacetonephosphate acyltransferase
- Glycerol-3-phosphate acyl transferase
- Glycerol-3-phosphate dehydrogenase-like protein
- Dihydroxyacetone kinase 1-like protein
- Putative phosphatidic acid phosphatase
- Diacylglycerol kinase
- Putative lipin
- Putative glycerophosphoryl diester phosphodiesterase
Sequence:
MAATAVKYAIGAGVAIFGGMVGFSYTNPAWTQRKFDASKCPPLKYESVPTREMCVQALKAHNSVANPLDVLIIGGGCVGAGSALDAVTRGLSVGMVDMGDYACETSSRSTKLIHGGIRYLQKAVFQADPMQLKLVAEALRERTIMIHQAPHLCHSLPTLVPCYHPIDIGMYWCGAKMYDIMAAFYGGTLEYSGFLFPYEAMKAYPKLRKTDQDNNALLGAVRYYDGQMNDARLCYSVAMTAACYGAATVNYARVKQMEVVKDDKGDELVRTIIEESVARKTIEVYSRSIINAGGPFSGEVEKLATSAEKQLDMFPAAGTHIVIDRKYCPREREAMVVPSNDDRVVFAIPWLGGCLLGTTDHKCEVQSNPPTPQADVDFLIENIRPFIGSVPPEAVRSAWTGVRPLAIPKAQKLKGGGTQNIVREHVIAVDPKSHMLNITGGKWTTYRKMAEEAVDELQKTLMKGKADFKPCCTTNLVLVGARNLDKVASTAPLGIPEDVHKHWRSNYGDRYGEVMAVAAKDSKLMARLAKDSPVVEAEVVYAAQGEHCEHVMDFIARRTRIAFVNAEQAEQVVPRVTELMGQVKGWGNSKRNVERAAAYSALASFKGR
Protein: Neurexin-3-beta (Neurexin III-beta) [Cleaved into: Neurexin-3-beta, soluble form; Neurexin-3-beta, C-terminal fragment (NRXN3-CTF)] (D0PRN4)
Organism: Gallus gallus (Chicken)
Function: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion (By similarity). Plays a role in angiogenesis.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MHLRTNPSICPGRRPAWTLWMCSLFWGCIVSSVWSSSNVASSASSSSSVSQAQYEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRTDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEESTPVNDGKYHVVRFTRNGGNATLQVDSWPVNEHYPTGNTDSERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDRGRLFQGQLSGLYYNGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTPTTSVPPEMSTTVMETTTTMATTTTRKNRSPPSIQTTDDIVSSAECSSDDEDFIDCEPSTGKSGGELVIPLLVEDPLDIPPIATRAPFITLPPTFRPLLTIIETTKDSLSMTSEAGLPCLSDQGSDGCDDDGLVISGYGSGETFDSNLPPTDDEDFYTTFSLVTDKSLSTSIFEGGYKAHAPKWESKDFRPNKVSETGRTTTTSLSPELIRSTASSSTGMVPKLPAGKMNNRELKPQPDIVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGIRRVPGASEVVRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDKEYYV
Protein: Putative transferase At1g60990, chloroplastic (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog COG0354) (Q681Y3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Folate-dependent protein involved in Fe/S cluster biogenesis. Functionally complements an E.coli mutant defective in ygfZ.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:21984653}.
Interaction partners:
- Putative transferase At4g12130, mitochondrial
- Glycine dehydrogenase
- Glycine dehydrogenase
- Threonylcarbamoyl-AMP synthase
- Threonylcarbamoyl-AMP synthase
- glutamate formimidoyltransferase
- Glycine cleavage system H protein 1
- Glycine cleavage system H protein 3
- Expressed protein
- AT5G45030 protein
Sequence:
MNLLQSCKDMAMMMRIDSVSHITNTALLPCLYNGTVLRRRSLSLRKCGFRERKFQLRCVSASSDSLQFDFSPPPIDHDFLDTISVSGGKVSEDGVVESFDNDDEALDAFDNGVVVVDLSHFGRIRVSGDDRAHFLHNQTTANFESLYEGQGCDTVFVTPTARTIDIAHAWIMKNAILLTVSPTTCQSIIEMLNKYIFFADKVEIKDITKQTCLFALAGPKSNQIMSKLNLGDLIGQPYGRHQHYSFDGMPITVGVGSLISDEGFTMLMSPGGAVSVWKTLLAEGAIPMGSVAWEKLRITQGRPAPERELSKEFNVLEAGLWNSISLNKGCYKGQETIARLMTYDGIKQRLCGLNLSAPSEPGSTITVDGKKVGKLTSYTGGKNGSGHFGLGYIKKQAASIGNTVTVGEDISGIVSEVPYLARQHPPSANSSS
Protein: Uncharacterized protein ORF-c40_009 (Q9UXG0)
Organism: Saccharolobus solfataricus (Sulfolobus solfataricus)
Interaction partners:
Sequence:
MGSATSNIRFCIKKKYIMIEVKLRAIKRLSNVYTRRVMIIEDWNGSSITTGNIELVKGSENQLPQWLAIILEGKKVAKIEDKISIEDLGRILFQERQNMNTPASLVPLGKDFTSRVQLYLETLRKDNNVESLEKLRKSIGILNEIIKIRLRKLIQLAFLNIDDQNLINGMTEEELLIYKTIKQLIKELYGDIIGNS
Protein: Trefoil factor 3 (Intestinal trefoil factor) (rITF) (Polypeptide P1.B) (rP1.B) (Q03191)
Organism: Rattus norvegicus (Rat)
Function: Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:1763017, ECO:0000269|PubMed:9299425}. Cytoplasm {ECO:0000250|UniProtKB:Q07654}.
Interaction partners:
- Mucin-2
Sequence:
METRAFWTTLLLVLVAGSSCKAQEFVGLSPSQCMVPANVRVDCGYPTVTSEQCNNRGCCFDSSIPNVPWCFKPLQETECTF
Protein: Ubiquitin-like domain-containing protein (Q585Z0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSAIPPPHYVRLRRYNLSIFVHCDVHNDTVQAIKERYGKLTGHIFYNARLYLGQQSLDDFLTLYGCGIEAEGAELVVVHSKGAKGDGTSEHIWETVEEAMAAPQGDSLNSPEVTAEGTAKLDSMEAAATSNEVGNQQQQQAADARGGTGAELNVGFVGV