wanglab/gogpt-training-data huggingface dataset:
Protein: Kinesin-like protein KIN-7B (NPK1-activating kinesin-2) (AtNACK2) (Protein STUD) (Protein TETRASPORE) (Q8LNZ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable plus end-directed motor protein that functions in the NACK-PQR (ANP3-MKK6-MPK4) MAP kinase signaling pathway, which is essential for somatic cell cytokinesis, especially for the cell-plate formation and its expansion. May regulate the activity and the localization of ANP3, probably by association through the non-catalytic region of the kinase. Functionally redundant with NACK1 and essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during microgametogenesis and megagametogenesis.
Subcellular location: Cytoplasm, cytoskeleton, phragmoplast {ECO:0000250|UniProtKB:Q8S905}.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase 3
- Mitogen-activated protein kinase kinase kinase 2
- Mitogen-activated protein kinase kinase 6
- Protein JASON
- 65-kDa microtubule-associated protein 1
- Mitogen-activated protein kinase kinase kinase ANP1
- 65-kDa microtubule-associated protein 3
- Protein GIGAS CELL1
- Mitogen-activated protein kinase 4
- SNARE-interacting protein KEULE
Sequence:
MMGPPRTPLSKIDKSNPYTPCGSKVTEEKILVTVRMRPLNWREHAKYDLIAWECPDDETIVFKNPNPDKAPTKYSFDKVFEPTCATQEVYEGGSRDVALSALAGTNATIFAYGQTSSGKTFTMRGVTESVVKDIYEHIRKTQERSFVLKVSALEIYNETVVDLLNRDTGPLRLLDDPEKGTIVENLVEEVVESRQHLQHLISICEDQRQVGETALNDKSSRSHQIIRLTIHSSLREIAGCVQSFMATLNLVDLAGSERAFQTNADGLRLKEGSHINRSLLTLTTVIRKLSSGRKRDHVPYRDSKLTRILQNSLGGNARTAIICTISPALSHVEQTKKTLSFAMSAKEVTNCAKVNMVVSEKKLLKHLQQKVAKLESELRSPEPSSSTCLKSLLIEKEMKIQQMESEMKELKRQRDIAQSELDLERKAKERKGSSECEPFSQVARCLSYHTKEESIPSKSVPSSRRTARDRRKDNVRQSLTSADPTALVQEIRLLEKHQKKLGEEANQALDLIHKEVTSHKLGDQQAAEKVAKMLSEIRDMQKSNLLTEEIVVGDKANLKEEINRLNSQEIAALEKKLECVQNTIDMLVSSFQTDEQTPDFRTQVKKKRLLPFGLSNSPNLQHMIRGPCSPLSGTENKDPESNVVSANSAPVSFGATPPKRDDNRCRTQSREGTPVSRQANSVDIKRMNRMYKNAAEENIRNIKSYVTGLKERVAKLQYQKQLLVCQVLELEANETGAASEYDATDESQMDWPLCFEEQRKQIIMLWHLCHISIIHRTQFYMLFKGDPADQIYMEVELRRLTWLEQHLAELGNASPALLGDEPASYVASSIRALKQEREYLAKRVNTKLGAEEREMLYLKWDVPPVGKQRRQQFINKLWTDPHNMQHVRESAEIVAKLVGFCDSGETIRKEMFELNFASPSDKKTWMMGWNFISNLLHL
Protein: Thioredoxin-like protein 2 (C0H561)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Thioredoxin peroxidase 1
- Thioredoxin reductase
- Thioredoxin reductase.
- Glutathione reductase
- Glutathione reductase.
- Peroxiredoxin
- Plasmoredoxin
- Glutathione peroxidase
Sequence:
MFFLQNLKKITHPKYLCTTIRRNVYTELNKIDDYLSKVNGNKLVVAQFGASWCAPCKKMKPVIEKLGEDNDNIESLYIDIDEFPELGENEDINELPTILLRKNGKYLDKIIGMNESDLIKAVEKHQSD
Protein: Seipin (Q54K07)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
- Diacylglycerol O-acyltransferase 2
- Apoptosis-inducing factor homolog A
Sequence:
MENIVSKSIKSCLNFFFKIVSFWFRLWLLPINSIFEWVMEKVKPILDPLFSFLEKNKSKLLKYSLLSIFYLSFLFFVTILSYYAIYATLVPKVSTEEPLFFDYSYKSTKKIVADVQAAVEFQKNKHYNIYLELELPESPKNQDIGMFMACMDIDDHDKWNPQKIHHTCRPAMLKYSSSLLKSLKSIIFSVPYLFGVYEEKQIIVLPMGENFVANRFYQTISASIQINNPEIQIYRASLKFLANLNGFDYYLYYYPITSFIVGCSMIYLCLVGVTLFIVVSLYLYRHFNKEEEKEEEGEEEDEEEEEVDQEFSESEYLVPENDDILVGEDQLSSSSYLHKQQKQPQQQQQQQSIPRRNGASSIPTTTAQKRKPIWEIEDENDNINNFGASSSSNTSAKTKTTTSSTSSSSSSNLKTTFLSNKDAEDKLGIFSSPKVAPQTSSSNKQDQYYKELDEAFSQSISNNDNIDNNNNDKNNNNNNNNNNNNNNNNNNNNNNNNNNIQYSWDNELKDFESQHQRSLTSSPLIRSTNNNSSGTSNNNNNNEKPILKKKTTFKYSSDEENNSNLKNNESDDGDNEKSNETSTTSSVNGNSTDSPRYMNTLILTTNSVGSSPQVSSSSTPIAVVSSLNDHEQLQQEQTIPSAILNQASDNTSSEQLQENEEGKEICDDNNNNNNNNNNNNNNNNNNNNNKNNNSDDVNNNNSVDDNKDQKENSNTGNDNSPSSESDQEIVENEETGNSGEWVKISDSSVRKRK
Protein: Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7) (Q13003)
Organism: Homo sapiens (Human)
Function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P42264}; Multi-pass membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:P42264}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glutamate receptor ionotropic, kainate 4
- Glutamate receptor ionotropic, kainate 1
- Glutamate receptor ionotropic, kainate 5
- Glutamate receptor ionotropic, kainate 2
- Glutamate receptor 1
- Glutamate receptor ionotropic, NMDA 2A
- Glutamate receptor ionotropic, NMDA 2B
- Voltage-dependent calcium channel gamma-2 subunit
Sequence:
MTAPWRRLRSLVWEYWAGLLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPIDSDDSRPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSESGLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRALTADYALLMESTTIEYVTQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFVYKLRKTAEREQRSFCSTVADEIRFSLTCQRRVKHKPQPPMMVKTDAVINMHTFNDRRLPGKDSMACSTSLAPVFP
Protein: Neuron navigator 2 (V9GWV3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
RTNLQYRSLPRPSKSNSRNGAGNRCSTSSIDSNMSSKSAGLPVPKLREPSKASLGSSLPGLVNQTDKEKGISSDSESVASCNSVKVNPATQPVSSSAQATLQPGTKYADVASPTLRRLFGGKPTKPIATAETMKSAVVISNPHATLTQQGNLESPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSGPSNSLTWGTSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGGLSHNSSPGPVASTKEDSLMPFVRTSSVKTTLSERYTPTSQLRTQEDAKEWFRSHSAGGLQDT
Protein: Glutathione S-transferase U4 (AtGSTU4) (EC 2.5.1.18) (GST class-tau member 4) (Glutathione S-transferase 22) (Q9ZW27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
Subcellular location: Cytoplasm, cytosol {ECO:0000305}.
Interaction partners:
- Glutathione S-transferase DHAR2
- Glutathione S-transferase DHAR1, mitochondrial
- Probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial
- Glutathione S-transferase F6
- Glutathione S-transferase DHAR3, chloroplastic
- Putative glutathione peroxidase 7, chloroplastic
- Glutathione reductase, chloroplastic
- Berberine bridge enzyme-like 22
- Glutathione S-transferase F11
- Glutathione synthetase, chloroplastic
Sequence:
MAEKEEDVKLLGFWASPFTRRVEMAFKLKGVPYEYLEQDIVNKSPLLLQINPVYKKVPVLVYKGKILSESHVILEYIDQIWKNNPILPQDPYEKAMALFWAKFVDEQVGPVAFMSVAKAEKGVEVAIKEAQELFMFLEKEVTGKDFFGGKTIGFLDLVAGSMIPFCLARGWEGMGIDMIPEEKFPELNRWIKNLKEIEIVRECIPPREEQIEHMKKVVERIKSA
Protein: A-agglutinin-binding subunit (P32781)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Receptor binding subunit of the a-agglutinin heterodimer. S.cerevisiae a and alpha cells express the complementary cell surface glycoproteins a-agglutinin and alpha-agglutinin, respectively, which interact with one another to promote cellular aggregation during mating.
Interaction partners:
- A-agglutinin anchorage subunit
- Pheromone alpha factor receptor
- Alpha-agglutinin
- Mating hormone A-factor 2
- Protein ASG7
- Barrierpepsin
- Alpha-factor-transporting ATPase
- Mating hormone A-factor 1
- Silenced mating-type protein A1
- Factor-induced gene 2 protein
Sequence:
MQLLRCFSIFSVIASVLAQELTTICEQIPSPTLESTPYSLSTTTILANGKAMQGVFEYYKSVTFVSNCGSHPSTTSKGSPINTQYVF
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (Q5XG46)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGVDLETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFKIGRQEVIKGWEEGVAQMSLGQRAKLTCSPDVAYGATGHPGVIPPNATLIFDVELIRIE
Protein: Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Neural ArgBP2) (nArgBP2) (Sorbin) (O35413)
Organism: Rattus norvegicus (Rat)
Function: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 (By similarity). May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (By similarity). Isoform 2 increases water and sodium absorption in the intestine and gall-bladder.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000269|PubMed:10521485, ECO:0000269|PubMed:15128873, ECO:0000269|PubMed:15659545, ECO:0000269|PubMed:16125169}. Apical cell membrane {ECO:0000250|UniProtKB:O94875}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:O94875}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:O94875}. Note=Detected in the stress fibers, synaptosomal cytosol, postsynaptic density fraction, Z-disks and intercalated. The CBL/PTK2B/ARGBP2 complex is recruited to lipid rafts following growth factor stimulation. In pancreatic acinar cells, localized preferentially to the apical membrane. Colocalized with vinculin and filamentous actin at focal adhesions and lamellipodia of pancreatic cells. {ECO:0000250|UniProtKB:O94875}.
Interaction partners:
- Vinculin
- PDZ and LIM domain protein 5
- E3 ubiquitin-protein ligase CBL
- GTP cyclohydrolase 1
- Vesicle trafficking 1
Sequence:
MNTDSGGCARKRAAMSVTLTSVKRVQSSPNLLAAGRESHSPDSAWRSYNGRNPETLNGDATYSSLAAKGFRSVRPNLQDKKSPTQSHITINGNSGGAVSPVSYYQRPFSPSAYSLPASLNSSIIMPHGRSLDSAETYSQHAQSLDGTMGSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDEDTDMYNTPYTYNAGLYNSPYSAQSHPAAKTQTYRPLSKSHSDNGTDAFKEATSPVPPPHVPPRPRDQSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPVSVYQSSIDRSLERPSSSASMAGDFRKRRKSEPAVGPPRGLGDHSSSRTSPGRADLPGSSSTFTTSFISSSPSSPSRAQGGDDSKMCPPLCSYSGLNGSPSSELECCGAYRRHLDVPQDSQRAITFKNGWQMARQNAEIWSSTEEAVSPKIKSRSCDDLLNDDCGSFPDPKTKSESMGSLLCDEGSKESDPMTWTSPYIPEVCGNSRSRLKHRSAHNAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYEKEQQHRGLLHGWSQSSTEEVPRDVVPTRISEFEKLIQKSKSMPNLGDEMLSPVTLEPPQNGLCPKRRFSIESLLEEETQVRHPSQGQRSCKSNTLVPIHIEVTSDEQPRTHMEFSDSDQDGVVSDHSDNVHVERSSFCSESDFDHFSFTSSESFYGSSHHHHHHHHHHGHFISSCKGRCPASYTRFTTMLKHERAKHENIDRPRRQDMDPGLSKLAFLVSPVPFRRKKVLTPQKQTEQAKCKASVVEALDSALKDICDQIKAEKRRGSLPDNSILHRLISELLPQIPKRNSSLNALKRSPMHQPFHPLPQDGAIHCPLYQNDCGRMPHSASFPDVDTTSSYHAQDYGSVLSLQDHESPRSYSSTLTDLGRSVSRERRGTPEKEVKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPVQPGEIGEAIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKRNTKGSEDYPDPPLPHSYSSDRIYSLSSNKPQRPVFSHENIQGGGEPFQALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL
Protein: HrpXo (Regulatory protein HrpX) (Q9ZIP8)
Organism: Xanthomonas oryzae pv. oryzae
Interaction partners:
Sequence:
MILSTYFAAISALSYAERLPTYTSRMLVGAWPQGLQHLQQRRDGQGAADGADDEVSLFGASGDALLILEYQEEAEDAYRQALKAMRGQQRQLRLLSCRNTAWLMLSQRRLSAALNCFAQLAMDRETPPSLCGESLLGKALTHFHLGQSTLALQTLERANEVLAELESGASDWLRVATALRLDMIAQLRIRRSDRMVDHVFWQATLRQEDAAHAFEPSDLRACIADLAESMPVLAQRMRHVRNLLRIVGGDTFGFDAQIDALPAAATGCPPCARQDAQVELALAALAVGRADLAERALAGAGRHHAPRWNLEFEYCQAKISQALGRTEQALLLYNRYALDAVQCLRSEVQAPRLLESGTPAHVSDDISARLPAKYRRAYSYMITNAHRSDLSINEVAAQIGVTGRALQQAFKSATGLSPTQVLRRYRMQSIRDELLAEGGCGSVLQAASRWGVGSRSALAKGYRQHFNEAPMETLQR
Protein: Spermatogenesis-defective protein spe-17 (P34890)
Organism: Caenorhabditis elegans
Interaction partners:
- Palmitoyltransferase spe-10
- Uncharacterized protein
- Serine protease inhibitor swm-1
- Transporter
- Sperm vesicle fusion protein fer-1
- Serine/threonine-protein kinase spe-6
- Spermatocyte protein spe-8
- Spermatocyte protein spe-27
Sequence:
MQMADIAKQREQPPRAMSTTSGSDVLKSTTTGTTTGTTKSSVHTSDTNYGVGSLRSDCSEEGFGSNLTPEEANWLNMARVFTKAEKPFKEQKTFRVARKLRTWRPRRSVTWSFLRRLYNGREDMKEDLIRDLADLEIEDKPV
Protein: Ciliated left-right organizer metallopeptidase (EC 3.4.24.-) (Leishmanolysin-like peptidase 2) (A0A1D5NSK0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays an essential role for patterning the left-right axis. Requires solely on the left side, downstream of the leftward flow, but upstream of dand5, a nodal inhibitor involved in left-right patterning.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Guanine nucleotide exchange C9orf72 homolog
Sequence:
MSFLLCIGILLLPWFPCVCGKCIFDQIQRSVNVVSPPTAQYASAYRFKTQRSKRHIMPMDNLQPIRIKIWIPSESPALSDWEREKLMSAVGEAVSEVSSLLSVKRVKDRLLLNRDVNKYCKFIWRNSSTLNHMKCGRAHENYRFESCLGVIIPDEHLDGCSVYPNPEHPVPTVLRPRGPGVPDADFLLYVFTHNTEKCRAESSVLAYTAHCQTGSDGRPLAGTMVICRETLKKERYTYQHFVKVTTVIHELFHVLGFSKELLSNWKDFGVDCWSHGQVTSTDQTGQVRLYSPTVIRAMQKHFNSTHTDLGAPLENKDAALDGLSSHWEARVLQGSIMAASLVEASLVRIDAITLAALQDTGWYSVNHSRAQSLVWGEGEGSDFGSVSACHNSSAFFCTGSGLGCHFLHLNKGECVTDQYLDGCHIFKPLANASECWIEDNARSGMNEGGGEIFGSDSRCFISNITRLNNVTAYTPVSGHCYRHRCTGINKYHIQVKDSDWMDCPAGTSIEVSGYQGFIFCPENRLCKYSDLAPPTSTQRTESLFSDTTAQSDLGMMEKDAAVQPSFTSLFLVSEAKISLAAVLSLMAVFALLSAAVLLYRKNLSVRVHAASYRTPLPHILYRN
Protein: RAS, guanyl releasing protein 3 (Q6NZH9)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
- Ras-related protein Rap-1A
- GTPase KRas
- GTPase HRas
- Ras-related protein Rap-1b
- Diacylglycerol kinase iota
- GTPase NRas
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- Son of sevenless homolog 1
- Son of sevenless homolog 2
- Kinase non-catalytic C-lobe domain-containing protein 1
Sequence:
MGSNGLGKAATLDELLSTCIEMFDDNGDLNDSYLPRIVLLMHRWYLSSTELAGKLLCMYRNASGESCDEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGHEKHISLMDISSVPSYDWMRRVTQRKKVSKRGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPSAQQRAEVITKFINVAQKLLQLKNFNTLMAVVGGLSHSSISRLKDTHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWMEENKVNVVKMHQLSVTLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWASEVVPKPDPTIINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMNYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRLARAPSLSSNPGSLPGSPALPPVQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAVWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPTVQAGVDVVDRGTAFEPDQDDGQDEAKQGGEDG
Protein: Uncharacterized protein (Q388L8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Treble clef zinc finger domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- AB hydrolase-1 domain-containing protein
- Ribosomal protein L22p/L17e
- Uncharacterized protein
- Uncharacterized protein
- Large ribosomal subunit protein uL4m
- Uncharacterized protein
Sequence:
MSSRFFQKYFIRCGNCQTIQRYAKGYKPIPNPILFDSDAHCRSYHRERRDCTGLTGTLVTCRCDKCARVHSHWTVMDFQEFLDAKLVMTPEERTALLWPGAGSRAEPSSGTSN
Protein: Caerulein (P86486)
Organism: Litoria peronii (Emerald spotted tree frog) (Hyla peronii)
Function: Induces contraction of intestinal smooth muscle in isolated guinea pig ileum.
Subcellular location: Secreted {ECO:0000269|PubMed:19642086}.
Interaction partners:
Sequence:
QQDYTGWMDF
Protein: SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1) (O94901)
Organism: Homo sapiens (Human)
Function: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration (By similarity). Involved in telomere attachment to nuclear envelope in the prophase of meiosis implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly (By similarity). Required for gametogenesis and involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis (By similarity). Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity). Required for efficient localization of SYNE4 in the nuclear envelope (By similarity). May be involved in nuclear remodeling during sperm head formation in spermatogenesis (By similarity). May play a role in DNA repair by suppressing non-homologous end joining repair to facilitate the repair of DNA cross-links.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}; Single-pass type II membrane protein {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}. Note=At oocyte MI stage localized around the spindle, at MII stage localized to the spindle poles. {ECO:0000250|UniProtKB:Q9D666}.
Interaction partners:
- Protein KASH5
- Nesprin-2
- Nesprin-1
- Emerin
- Prelamin-A/C
- SUN domain-containing protein 2
- Nesprin-4
- Nesprin-3
- Lamin-B1
- Telomere repeats-binding bouquet formation protein 1
Sequence:
MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
Protein: Peroxisomal carrier protein, putative (AFU_orthologue AFUA_1G03440) (Q5BGS3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
Sequence:
MAGQSKPALSPWGSAVAGATGAVLANAIVYPLDLVKTKLQVQVKKAGEAESKDSDDVHYKSTWDAITKIMDKEGVEGLYSGMAGSLIGVASTNFAYFYWYSVVRTLYMASERVPKPPGTAIELSLGAVAGAVAQIFTIPVAVITTRQQTQPKDDKKGLIETGREVVNSEDGWSGLWRGLKASLILVVNPAITYGAYQRLKDIIFPGKKSLKPWEAFLLGALSKAMATIATQPLIVAKVGLQSRPPPARNGKPFKTFSEVMRFIVENEGPLSLFKGIGPQILKGLLVQGLLMMTKERMELLFIVLFAYLKGLREKKLRKAVDAAASKAQASLPATLK
Protein: Peroxisomal membrane protein PEX16 (Q9VPB9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Peroxisome membrane {ECO:0000256|RuleBase:RU365003}.
Interaction partners:
- Peroxin-19
- Peroxisomal biogenesis factor 3
- Peroxisome assembly protein 12
- Peroxisomal membrane protein PEX13
- Peroxin 11
- RING-type E3 ubiquitin transferase
- Peroxisomal targeting signal 1 receptor
- Peroxisomal ATPase PEX6
- Peroxin-7
- ATP-binding cassette sub-family D member 3
Sequence:
MDTLKGMLKAYEAWVGKNPDVVGDFETTAKWVSYFIAGRISSSNVVSELVYTLSNMLVFYNDRIIEKARNSEENSVIHLQSKLCYRLKVTLTTLEYSEVFIEISARRLFGQSGKWLVIALIQAFKAAGRFFILKHSTSDIITSPPIAALNRRAKQRKNSGDGVASSTNDLLQSQHSITFQLKRSGRVIRKVEGAPPLQYRDFKLHIDNNEAAKTQIPRKLLQAEYLYISKPLIHLVAMGLFGRRSWKQYMVALSIDLYSIHLYRQHRDLMSKQQKLELSRRCINIMYFLVRSPFYDSFTKSRLERILDFVATSVPIAKVVAKPLKDYIPTWQSTYFYLWST
Protein: Suppressor of fused homolog (F7FL48)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR011844}. Nucleus {ECO:0000256|PIRNR:PIRNR011844}.
Interaction partners:
Sequence:
MAELRPSVAPGPAAPPASGPSAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNMGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICLGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINSQRQNGLTYDRAPSRKDSLGSDISTAVIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQVRSSFSSLFFSFHSSLAACPPSQSLWYPC
Protein: Serine protease inhibitor Kazal-type 2 (Q8BMY7)
Organism: Mus musculus (Mouse)
Function: As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects. May be involved in the regulation of serine protease-dependent germ cell apoptosis. It also inhibits trypsin.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P20155}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:28554943}.
Interaction partners:
- Serine protease inhibitor Kazal-type 1
- Serine protease inhibitor Kazal-type 13
Sequence:
MLRLVLLLLVTDFAASHETLDSSDSQIMKRSQFRTPDCGHFDFPACPRNLNPVCGTDMNTYSNECTLCMKIREDGSHINIIKDEPC
Protein: Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 (B1AR10)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTSRHSSGGGGGAGGGSSGGGGGGSSSASGGGGGTGGGSGNSFLSGRRSRSASPSTQPEKHPTHHEKGQKKSRKDKERLKQKHKKRPESPPSVLAPPAVPTADKVSSATSSSHHEASTQETSESSRDSKGRKSSSHSLSHKDKKLGTGKGVSSFTSASSSSSSSSSSSSSSSGGPFQPAGSSLQSSPDFAAFPKLEQPEEDKYPKPADPTPPAPPSPTAPEPPKADLFEQKVVFSGFGPIMRFTTTASSSSRARAPSPGDYKSPHITGAGASAGTHKRMPALSATLGPAEEAPETTLKEKKHKASKRSRHGPGRPKGSRGKEGASGPTASLPAAQLAGFTATAASPFSGGSLVSAGLGGLASRTFGPSGSLPSLSLESSLLGAGIYTSNKDPISHGGGMLRAVCSTPLSSSLLGPTGTSALPRLSRSPFTSTLASSSASISTTQVFSLAGSTFSLPSSHIFGTPMGTVNPLLTQAESSHTEPDLEDCSFRCHGTSPQESLSSMSPISSLPALFDQTSAPCAGGQLDSTAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQVLNVQLSVPFPALPAALPATNGPIPGPYGLLPQAGSSDSLSVSKSPPGKNSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGATGLGAMPMAEGLLGGLAGSGSLPLNGLLGGLNGAAAPNPAGLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQMQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGSNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLPGADASGNGPKGGTADKGASTSQEKG
Protein: Protein FLX-like 1 (AtFLXL1) (Q93V84)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has no transcriptional activation activity.
Interaction partners:
- Flowering time control protein FCA
- Flowering time control protein FPA
- FRIGIDA-like protein 1
- Cleavage and polyadenylation specificity factor subunit 2
- Protein FRIGIDA-ESSENTIAL 1
Sequence:
MSGRNRGPPPPSMKGGSYSGLQAPVHQPPFVRGLGGGPVPPPPHPSMIDDSREPQFRVDARGLPPQFSILEDRLAAQNQDVQGLLADNQRLAATHVALKQELEVAQHELQRIMHYIDSLRAEEEIMMREMYDKSMRSEMELREVDAMRAEIQKIRADIKEFTSGRQELTSQVHLMTQDLARLTADLQQIPTLTAEIENTKQELQRARAAIDYEKKGYAENYEHGKIMEHKLVAMARELEKLRAEIANSETSAYANGPVGNPGGVAYGGGYGNPEAGYPVNPYQPNYTMNPAQTGVVGYYPPPYGPQAAWAGGYDPQQQQQQQPPPQGQGHR
Protein: Alkanal monooxygenase (EC 1.14.14.3) (Bacterial luciferase) (Q9S3Z1)
Organism: Aliivibrio fischeri (Vibrio fischeri)
Interaction partners:
Sequence:
MKFGNICFSYQPPGETHKQVMDRFVRLGIASEEVGFDTYWTLEHHFTEFGLTGNLFVAAANLLGRTKTLNVGTMGVVIPTAHPVRQLEDVLLLDQMSKGRFNFGTVRGLYHKDFRVFGVDMEESRAITQNFYQMIMESLQTGTISSDSDYIQFPKVDVYPKVYSKNVPTCMTAESASTTEWLAIQGLPMVLSWIIGTNEKKAQMELYNEIATEYGHDISKIDHCMTYICSVDDDAQKAQDVCREFLKNWYDSYVNATNIFNDSNQTRGYDYHKGQWRDFVLQGHTNTNRRVDYSNGINPVGTPEQCIEIIQRDIDATGITNITCGFEANGTEDEIIASMRRFMTQVAPFLKEPK