wanglab/gogpt-training-data huggingface dataset:
Protein: Magnetosome protein MamG (Q6NE75)
Organism: Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)
Function: Plays a role in regulating magnetite crystal size.
Subcellular location: Magnetosome membrane {ECO:0000269|PubMed:18539817}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes as a filament-like structure in a straight line running through the center of the cell, in a position that corresponds to magnetosomes. {ECO:0000269|PubMed:18539817}.
Interaction partners:
Sequence:
MIKGIAGVGGTALGVGGGVAAPPVSAAAVGSTLLAGKGVCLGLGLGLGAWGPVLLGVAGLACAASLCDYLKNRKAQAEASAEPA
Protein: Transcription factor (Q9NFL3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAATPPMPPGSNTHQLNGKTVGKGNPLAEAINQHFQRKKQNQHQSPNPSPNPNPNSPASRSGSYEQLELLDHATHPQQQQEASSGKAKPSCHCTNISIMHLFHEMKQEFPTIPDAIVTQCVNENCHQRENCIQMLRKELALHPIPVQSYPAKVLQQQQQQHHQNRQAKPPTPLKPSRIAPPQPEAVLSNGVATPPGVGSPHPDTQPRPRPTTLNLQRQFSTQLQQKIMQRQQRQQRDHQPAQLTPTSLSKPLRRAPPLPPPPKPKPGSFSNDSSCLTSPMSSSESELSLNAVPLSSPTSAAATAAAASAAIASTQQQPSPVRHRSVITLQPEPPYARDFRSIDFPPTTACTPRLPSPSSAASPSAPGGRKSFTSLNLTLRQPTGSAQSAIDITAGPAPSGQGSGITYSSVSFDARRGTQKNFQLTVTDEGSVFSAGSVRPRTLYATPCEPVTSVPANQQPPPPAAVVADGLGDADMTSDVFPYPTQEQNHIVASNYSNNHAVSDNNNIGISNSTDSSPTMPLYEGVMEECDREARAATIERQKQRRDKLANALRDNKKRLLVLEQEINILTEPVPVGESERLDRDIKQLTEDCNRLLDCLNEPQANGPGPAANPTNRQHLLPGSNASQQQPQQQPQPFPRQRQSARVQAPPSSLRLHSVPAAPNSQPVQDFGQHHSSAPTSACLTPQMQSQQQLLQLQQEPPPTYAQYYQFQQYLQQQRQQQLQQQMQQQQQLQQQMQQQQQPQPQQEEEFLSDSDVDEEEETLDSWACNMCTFRNHPQLNICEACENVRIQPGMIRIVPSGGGAAAAAATPPGSIEQQQQPSQQPYALHT
Protein: RNA polymerase II transcription factor SIII p18 subunit (Ubiquitin-like domain-containing protein) (G5ECR7)
Organism: Caenorhabditis elegans
Interaction partners:
- Cullin-2
- Cullin-5
- RING-box protein 1
- Elongin-C
- Elongin-C
- RING-box protein 2
- Leucine-Rich Repeat protein
- Ubiquitin-like protein NEDD8
- von Hippel-Lindau tumor suppressor homolog
- Transcription elongation factor B polypeptide 3
Sequence:
MSQQELFFEVRRNRSHIYLDAEESHSVMELKLMLAGITRDPVNHMELWKLDEDGNKSQLLHDTATLSDAGFSSTNAKAQCPAALGLRLTNAEEHLTISDVSTAPPIPDTMRQEQAPQE
Protein: CPG4 domain-containing protein (Q18743)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTNRLLLLILFSGTVAFDHPTHTLDPAIPTVAPHTTDSSADSCAGQCAFQFMDNIRSQIGQDRASSLMQLNFNDFLTSFSNTTFFEKFCVIYHNFQNCASKCTPGFLHQLLMRSSEIIDQYCVYNFDAIREKFPCLIKMKPNKECVKTCTPHHNAISSMTENFKNLVLSGDTTKAEQYLAQGCEYITCTLHCDVPTIAHECDSETAQLVIDLTRKSFASMEKMALDTNAVAKWPQVCADIKTYRMPTPSIPPKNTDVVAQSNSVADQPISHPKLVQAPLIRASSILSISIASLVPFVLFF
Protein: Probable inactive receptor kinase At5g67200 (Q93Y06)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MTLNFFLPFFFFFILLRVSAGAEPNYFNSLLPSDAVALLSFKSTADLDNKLLYSLTERYDYCQWRGVKCAQGRIVRLVLSGVGLRGYFSSATLSRLDQLRVLSLENNSLFGPIPDLSHLVNLKSLFLSRNQFSGAFPPSILSLHRLMILSISHNNFSGSIPSEINALDRLTSLNLDFNRFNGTLPSLNQSFLTSFNVSGNNLTGVIPVTPTLSRFDASSFRSNPGLCGEIINRACASRSPFFGSTNKTTSSEAPLGQSAQAQNGGAVVIPPVVTKKKGKESGLVLGFTAGLASLIVLGLCLVVFSLVIKKRNDDGIYEPNPKGEASLSQQQQSQNQTPRTRAVPVLNSDTESQKREKEVQFQETEQRIPNSGNLVFCGESRSQGMYTMEQLMRASAELLGRGSVGITYKAVLDNQLIVTVKRLDAAKTAVTSEEAFENHMEIVGGLRHTNLVPIRSYFQSNGERLIIYDYHPNGSLFNLIHGSRSSRAKPLHWTSCLKIAEDVAQGLYYIHQTSSALVHGNLKSTNILLGQDFEACLTDYCLSVLTDSSSASPDDPDSSSYKAPEIRKSSRRPTSKCDVYSFGVLIFELLTGKNASRHPFMAPHDMLDWVRAMREEEEGTEDNRLGMMTETACLCRVTSPEQRPTMRQVIKMIQEIKESVMAEENDPFR
Protein: WAS/WASL-interacting family protein (F4HYQ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ribosome biogenesis protein BOP1 homolog
- Putative WD-repeat membrane protein
- Periodic tryptophan protein 2
- Bystin
- Ribosome production factor 2 homolog
- U3 small nucleolar RNA-associated protein 18 homolog
- DEAD-box ATP-dependent RNA helicase 16
- Ribosome assembly factor mrt4
- Protein TORMOZ EMBRYO DEFECTIVE
- Peter Pan-like protein
Sequence:
MSEETPKLFTNKPKKKAIIAQLKHVEANFNNPTVPPSSKPSPAAAAAASYTMGGGSVPPPPPPKESFARRYKYVWPLLLTVNLAVGGFCSSLDENRIVFSFIFMMLRVIYDSYLFFRTKKKDLDPVVEETAAKSSSVAAPVTVEKTLSSTVVAEPVVIKAREPIPEKQQRELFKWMLEEKRKVNPKNAEEKKRNDEEKAILKQFIGSKTIPTF
Protein: Semaphorin-1A (CeSema) (Q17330)
Organism: Caenorhabditis elegans
Function: May function in growth cone guidance.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Plexin-2
- Sema domain-containing protein
- Semaphorin-2A
- C4H2-type domain-containing protein
- Netrin unc-6
- Ras-related protein ced-10
Sequence:
MRRILTLLLLFNVVRSSEAITGGVVNLRPKQIINSVGIGDRFGGIGTSSDESDHFKLLAADGDSLLVGARNAVYNLSLSTLSVNHKIDWKPPAEHIEECIMKGKSKTDCQNYIRVLARKSAGVSLVCGTHAFSPKCREYTVTEFGIRNTRQFDGQGISPYDPKHNSSALYVPGTNQLFVATVTDFVGNDALIYRKTIDETPSSKSAANIRTQSYDARVLNAPNFVATFAYKEHVYFWFREIASEAIDNNEEPQIYARVARVCKNDKGGARPANERWTSYLKARLNCSLPSGSSPFYFNELKAVSDPIDAGNNNHVVYTVFSTPDSDVRMSAVCKFSMKKIREEFDNGTFKHQNNAQSMWMAFNRNEVPKPRPGSCSPDSTKLPENTVSFILHHPLLHRPIPSVAAPLLVEGADRADLTQITVLPRVRAVGGHNYDILFIGTSDGKVLKVVEVDGNATVIQSATVFQRGVPIVNLLTTKESVVIVSADEIASLPVHNCAQQTSCSKCVQLQDPHCAWDSSIARCVHGGSWTGDQFIQNMVFGQSEQCPEGIIVREVFDDNESEAQPEAVSRSGYPKEHSTITVVLVAAVASLISLIIGAFIGIRVNRWAATSEPHRSASSTSGSDYDSFGRARLTRHDSLTTATKVDHGFVPQSKQSVDATSLVMSINATHHPMSMSQHGSGINTPSRDKNAIVTSINQNTLPRDYKVKKVYL
Protein: Actin-binding LIM protein 1 (Q3KR72)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQDRQSLGESPRTLSPTPSAEGFQDGRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPDQGINIYRKPPIYKQHAALAAQNKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAIGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKENRERASLLASRYDSPLHSASHAPSSKTSSLPGYGKSGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF
Protein: Arsenical-resistance protein 2 (Q06597)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in resistance to arsenic compounds.
Interaction partners:
- Arsenical-resistance protein 3
- Arsenical-resistance protein ARR1
- Metal resistance protein YCF1
Sequence:
MVSFITSRQLKGLIENQRKDFQVVDLRREDFARDHITNAWHVPVTAQITEKQLNQLIKGLSDTFSSSQFVKVIFHCTGSKNRGPKVAAKFETYLQEEDITSKFESCILVGGFYAWETHCRESNLKLIVSG
Protein: Bidirectional sugar transporter SWEET5 (AtSWEET5) (Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 5) (Protein VEGETATIVE CELL EXPRESSED 1) (AtVEX1) (Q9FM10)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates both low-affinity uptake and efflux of sugar across the plasma membrane (By similarity). May play roles in nurturing the male gametophyte.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
Interaction partners:
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
- Ankyrin repeat protein
- TORTIFOLIA1-like protein 3
- Actin-related protein 2/3 complex subunit 2B
- S-protein homolog
- Sugar transport protein 5
- Putative nucleolar protein 5-3
- Alcohol dehydrogenase-like protein
- Alcohol dehydrogenase-like protein
- Probable methyltransferase PMT2
Sequence:
MTDPHTARTIVGIVGNVISFGLFCAPIPTMVKIWKMKSVSEFKPDPYVATVLNCMMWTFYGLPFVQPDSLLVITINGTGLFMELVYVTIFFVFATSPVRRKITIAMVIEVIFMAVVIFCTMYFLHTTKQRSMLIGILCIVFNVIMYAAPLTVMKLVIKTKSVKYMPFFLSLANFMNGVVWVIYACLKFDPYILIPNGLGSLSGIIQLIIYITYYKTTNWNDDDEDKEKRYSNAGIELGQA
Protein: Ribosome-recycling factor, mitochondrial (RRF) (mtRRF) (Ribosome-releasing factor, mitochondrial) (Q96E11)
Organism: Homo sapiens (Human)
Function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:18782833}.
Interaction partners:
- Ribosome-releasing factor 2, mitochondrial
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein bL20m
- Large ribosomal subunit protein bL32m
- Large ribosomal subunit protein bL21m
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL9m
- Small ribosomal subunit protein bS6m
Sequence:
MALGLKCFRMVHPTFRNYLAASIRPVSEVTLKTVHERQHGHRQYMAYSAVPVRHFATKKAKAKGKGQSQTRVNINAALVEDIINLEEVNEEMKSVIEALKDNFNKTLNIRTSPGSLDKIAVVTADGKLALNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPQVTREHREMLVKLAKQNTNKAKDSLRKVRTNSMNKLKKSKDTVSEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG
Protein: Kinesin-like protein CIN8 (Chromosome instability protein 8) (P27895)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for assembly of the mitotic spindle. Interacts with spindle microtubules to produce an outwardly directed force acting upon the poles. Following spindle assembly, CIN8 and KIP1 apparently act to oppose a force that draws separated poles back together. This force seems to be mediated by KAR3.
Subcellular location: Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:1618897, ECO:0000269|PubMed:25313961}. Mitochondrion {ECO:0000269|PubMed:14576278}. Note=Spindle microtubules that lie between the poles. {ECO:0000269|PubMed:1618897}.
Interaction partners:
- Anaphase spindle elongation protein
- Serine/threonine-protein kinase MEC1
- Serine/threonine-protein kinase RAD53
- Tubulin beta chain
- Cell cycle serine/threonine-protein kinase CDC5/MSD2
- Kinesin-like protein KAR3
- Securin
- Tubulin alpha-3 chain
- Dynein heavy chain, cytoplasmic
- Mitotic spindle checkpoint component MAD2
Sequence:
MPAENQNTGQDRSSNSISKNGNSQVGCHTVPNEELNITVAVRCRGRNEREISMKSSVVVNVPDITGSKEISINTTGDTGITAQMNAKRYTVDKVFGPGASQDLIFDEVAGPLFQDFIKGYNCTVLVYGMTSTGKTYTMTGDEKLYNGELSDAAGIIPRVLLKLFDTLELQQNDYVVKCSFIELYNEELKDLLDSNSNGSSNTGFDGQFMKKLRIFDSSTANNTTSNSASSSRSNSRNSSPRSLNDLTPKAALLRKRLRTKSLPNTIKQQYQQQQAVNSRNNSSSNSGSTTNNASSNTNTNNGQRSSMAPNDQTNGIYIQNLQEFHITNAMEGLNLLQKGLKHRQVASTKMNDFSSRSHTIFTITLYKKHQDELFRISKMNLVDLAGSENINRSGALNQRAKEAGSINQSLLTLGRVINALVDKSGHIPFRESKLTRLLQDSLGGNTKTALIATISPAKVTSEETCSTLEYASKAKNIKNKPQLGSFIMKDILVKNITMELAKIKSDLLSTKSKEGIYMSQDHYKNLNSDLESYKNEVQECKREIESLTSKNALLVKDKLKSKETIQSQNCQIESLKTTIDHLRAQLDKQHKTEIEISDFNNKLQKLTEVMQMALHDYKKRELDLNQKFEMHITKEIKKLKSTLFLQLNTMQQESILQETNIQPNLDMIKNEVLTLMRTMQEKAELMYKDCVKKILNESPKFFNVVIEKIDIIRVDFQKFYKNIAENLSDISEENNNMKQYLKNHFFKNNHQELLNRHVDSTYENIEKRTNEFVENFKKVLNDHLDENKKLIMQNLTTATSAVIDQEMDLFEPKRVKWENSFDLINDCDSMNNEFYNSMAATLSQIKSTVDTSSNSMNESISVMKGQVEESENAISLLKNNTKFNDQFEQLINKHNMLKDNIKNSITSTHSHITNVDDIYNTIENIMKNYGNKENATKDEMIENILKEIPNLSKKMPLRLSNINSNSVQSVISPKKHAIEDENKSSENVDNEGSRKMLKIE
Protein: Inositol-3-phosphate synthase isozyme 2 (AtIPS2) (MIP synthase 2) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase 2) (AtMIPS 2) (MI-1-P synthase 2) (Q38862)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18603618, ECO:0000269|PubMed:20215587}.
Interaction partners:
- Inositol-phosphate phosphatase
- Phosphatase IMPL1, chloroplastic
- Bifunctional phosphatase IMPL2, chloroplastic
- Inositol-3-phosphate synthase isozyme 1
- Inositol 3-kinase
- Probable inositol 3-phosphate synthase isozyme 3
- Inositol-pentakisphosphate 2-kinase
- Sulfoquinovosyl transferase SQD2
Sequence:
MFIESFKVESPNVKYTENEINSVYDYETTEVVHENRNGTYQWVVKPKTVKYDFKTDTRVPKLGVMLVGWGGNNGSTLTAGVIANKEGISWATKDKVQQANYFGSLTQASSIRVGSYNGEEIYAPFKSLLPMVNPEDVVFGGWDISDMNLADAMARARVLDIDLQKQLRPYMENMIPLPGIYDPDFIAANQGSRANSVIKGTKKEQVDHIIKDMREFKEKNKVDKLVVLWTANTERYSNVIVGLNDTTENLLASVEKDESEISPSTLYAIACVLEGIPFINGSPQNTFVPGLIELAISKNCLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVASNGILFEPGEHPDHVVVIKYVPYVADSKRAMDEYTSEIFMGGRNTIVLHNTCEDSLLAAPIILDLVLLAELSTRIQFKAEGEGKFHSFHPVATILSYLTKAPLVPPGTPVVNALSKQRAMLENILRACVGLAPENNMIMEYK
Protein: Rifin (Q8I2C7)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKLHYTKILLFFFPLYILVYSKNKPSITPHHTQTNRSLCECDTQSTNYNNDEDIKSVKEIFDRQTSQRFEEYEERMQEKRQKRKEQRDKNIQEIIEKDRMDKLLAEKVEKGCLRCGCGLGGVAAGVGIFGTVAVKELTKASTVAAIAAAQEAAAAKGAVAGAEAGIKTVISGLQKLDISTLNGQTLVSYFDTTDYTNFKTIAHAINTQYDPSPCVLGRSGASESFCSWVRANFFAPQEISGKVSSTYESIEIGVTSIVSDAKKAAAAAVKKATDEVIKNSTAAAESTYAGCQTAIIASVVAIIIIALVMIIIYLVLRYRRKKKMNKKAQYTELLNQ
Protein: Wiskott-Aldrich syndrome protein family member (WASP family protein member) (H5V8D0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367034}.
Interaction partners:
Sequence:
MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIGDRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQCDKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAAGRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGIQLVKIQTVGEADIDLRHSTLDAHHQVVDMGVYDTRPPRPNSIELNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQSHALYGQTGQGVMSPEPIYGPGTPSRNKPRPSQPPPAPPSNGSGGGTPTASNANTPTRGRSMSTSRDALPPPPPVPDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSVQNANDMVMTQLSNTFHSIGMTGNQLNSLSDLPPPPPVPDQHSPKMSPPNAAPPPPPPPPPVEEGMGSGNQHTLRPHQILPKSLANGEMQQPGQQNGVPHIVAPKKMLPPFHDPRNDLMKAIRDGITLRKVEKSEQKEIERNAAPLDVASILARRVAIELSESEDSDSEDDSEGWMEPNETSA
Protein: PDZ domain-containing RING finger protein 4 (Ligand of Numb protein X 4) (SEMACAP3-like protein) (Q6ZMN7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGFALERFAEAVDPALECKLCGQVLEEPLCTPCGHVFCASCLLPWAVRRRRCPLQCQPLAPGELYRVLPLRSLIQKLRVQCDYRARGCGHSVRLHELEAHVEHCDFGPARRLRSRGGCASGLGGGEVPARGGCGPTPRAGRGGGARGGPPGGRWGRGRGPGPRVLAWRRREKALLAQLWALQGEVQLTARRYQEKFTQYMAHVRNFVGDLGGGHRRDGEHKPFTIVLERENDTLGFNIIGGRPNQNNQEGTSTEGIYVSKILENGPADRADGLEIHDKIMEVNGKDLSKATHEEAVEAFRNAKEPIVVQVLRRTPLSRPAYGMASEVQLMNASTQTDITFEHIMALAKLRPPTPPVPDICPFLLSDSCHSLHPMEHEFYEDNEYISSLPADADRTEDFEYEEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSSNNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQDTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCKIRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQNIMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIMEHPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNLRSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKLPDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPVRDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLECLKESPQSGSEGKKEINIIELSHKKMMKKRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV
Protein: Uncharacterized ATP-dependent helicase C144.05 (EC 3.6.4.-) (Q9UTL9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MDRTKRRKIEKEASLLNERNNLLESDFANCYRAFQHQLKLDQQIWRGPEDELNRLKSTIYPVVFWVDGSEKLHAYSFTQRKISLAKNLIPLFSVDLNKDTYSALKAPLKIWSKLWEDNRRLKKIIKYTSYVTVKGSELILSFGISILDSFLAPQDAILSSGSSSSYTALLDYTFLPSEDEEYSCLDINTALFYDCARKLAKSLRFANVSRDPRLSSELLPFQMRVLEWMKRREEEKFLTSNDLPPLWYHCKSLFDDRMVYVNHVYGYMTFSKEKTYLLASGDIRGGILADEMGMGKTLEVLGLVLHHQLPISLTDTCTFDQVVGKNVKYSKATLIITPSTILDQWLSEIDLHVPSLKVFHYQGIRKSNGLKSAKIFLDCDIVVTSYSDLRFELLYTESHSRTLRHEKRHVSPKSPLIDVCWWRICVDEAQMVETSQSNVAQMIYRIPRVNCWTVSGTPVRSEVDDLFGLLFLLRYSPMYLYKKQAWMQIIEKKRVREFCDLFGSLVCRHSKQDVEEELKLPPQHRICMTTRLSVVEETNYQDLLSEAAKSLHFFKDRNLDLCDEESMRRWLVRLRQACCHPQVGFGNKSAFGGGPMKSINDVLVFMLEQTNSTFSSLNRKLYSDKIIVGQIYDHIKDYNKALAIWSEVRIPVELAVKELENVIYNSKYEDHGKNLPINYFGLDHFIHLRVWYVLLHKIYFFIASAYFSLKNEKFENEFYLLAQDLRRKIMSDVIIKTSKHLEEFSEKFIPKKLVKIPRLQKSYAKGLITGHGIIEDYNRLYKELNDQKEVLIKFRDRLIHLMKLPLLDQESDPTGDEYEESLNAQSEISYCIDVYRQMLSDRVAAVSGTINTFVSHETELEKYKLIESIKKSEKSLDKQAEERDKKYLLYFEEREEARPKADQYGSLINIVSRLLDASNRSTSSFETSKNMEEYERIDAMAKEQSRICQKLEKELSIIQLTYNSRIEYYKQLQEISDSLMPPPVSNISLNNYVKDDEKKQKFLNSVIIKASVILEKEISEKQDEASQTTNVAELVNQKISEMNIPGHIHLLRELEEEKSNTQRKIAHFESRRRYLTNLYEHIVLKAESHQICIICRDIIKQGFITTCGHLYCSFCLEAWLKHSSSCPMCKTKLNKNNAYYIGESRDIYSRQEFVTGFNKRDERLEILDDEAYRQISNMELKESFGSKIDTISKHLLYLKHNELYPKVVVFSQWLDVLDVLHKSFEANGIVFIRFDGKSKNTCLKRFKEERSLQVLTLHARSQSSGLTLTNATHVFMCEPLLNSGIEMQAISRVHRIGQTRPTFVYYYIVEDTVEGHILNLSLTKHEQLDKLGLDVPLVGNINRTTEASSGGEQVDAAEIKDCLKMALKRLTTEDS
Protein: Ubiquitin-conjugating enzyme E2 25 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 25) (Q93571)
Organism: Caenorhabditis elegans
Function: Catalyzes the covalent attachment of ubiquitin to other proteins (Potential). Required for the maintenance of neuromuscular function.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12763049}. Nucleus {ECO:0000269|PubMed:12763049}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 J2
- E2 ubiquitin-conjugating enzyme
- Ubiquitin-conjugating enzyme E2 1
- E2 ubiquitin-conjugating enzyme
- Probable ubiquitin-conjugating enzyme protein 17
- E2 ubiquitin-conjugating enzyme
- Ubiquitin-conjugating enzyme E2 G2
- E1 ubiquitin-activating enzyme
- Ubiquitin-conjugating enzyme E2 2
- Ubiquitin-conjugating enzyme E2 21
Sequence:
MACLRKLKEDIQVLEKLFPKNHNRFQILSASVDELSMKFINAENKGIIVTANIQENYPRQPPIWFSESDDVPVIGMSLQRLTETEESTNILHQVHRLVSDLCSFYNLQMPCELPQIAPPVRDDIDEGRGSDISDTTSEPIDDDMAGDGEVDDDDEEEEDDEDADGDIEIVEMAEEDPTSQHDVGVSKEGLDMLDKVSKINRQQHLDGKVQGSITATDRLMKEIRDIHRSEHFKNGIYTFELEKEENLYQWWIKLHKVDEDSPLFEDMKKLKKDHNQDHLLFSFTFNEKFPCDPPFVRVVAPHINQGFVLGGGAICMELLTKQGWSSAYSIESCILQIAATLVKGRARISFDAKHTSTYSMARAQQSFKSLQQIHAKSGWYTPPKTEG
Protein: Mediator complex subunit 12 (D3ZDE6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAFGILSYEHRPLKRLRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLSDTGRRKSLMNQKDNFWLVTARSQSAINTWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKKKNTADPFTEWTQIITKYLWEQLQKMAEYYRPGPAGSGVCGSAIGPLPHDVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLDGVNSHSSHVISAQSTSSLPTTPAPQPPTSNTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGTPGPRPPSPFDDPADDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKDVKPPPKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFVFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVPGGTEELPEEEGGGGSSGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDSEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLLENIAKATIEVFQQSAETGSSSGSTASNIMNDVFEMVILDISLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGERQSDSLEKVHQLLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPALLEPEKKAPEPPKTDKPGTAPPSTEERKKKSTKGKKRSQPATKSEDYGMGPGRSGPYGVTVPPDLLHHANPGSISHLSYRQSSMGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTTVMGLEPSSYKTSVYRQQQPTVPQGQRLRQQLQAKIQSQGMLGQSSVHQMTPSSSYGLQSSQGYTSYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMMGTMTPLSAQGVQAGVRSTSILPEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQPQQQQPHQQQQQAAPPQPQPQSQPQPHRMGT
Protein: 8-hydroxyquercetin 8-O-methyltransferase (EC 2.1.1.88) (7,8,4'-trihydroxy-flavone 8-O-methyltransferase) (EC 2.1.1.-) (8-hydroxy-flavone 8-O-methyltransferase) (EC 2.1.1.-) (Flavonoid 8-O-methyltransferase) (Q6VMW0)
Organism: Mentha piperita (Peppermint) (Mentha aquatica x Mentha spicata)
Function: Flavonoid 8-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as pebrellin, aroma compounds which contribute to the flavor of peppermint, and exhibit pharmacological activities such as anti-allergic, anti-oxidant, antibacterial, anti-proliferative, and anti-inflammatory effects. Catalyzes S-adenosylmethionine-dependent regioselective 8-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates, including 7,8,3'4'-tetrahydroxy-flavone, 7,8,4'-trihydroxy-flavone and 8-hydroxy-flavone 7-methyl ether.
Interaction partners:
Sequence:
MALPNGISSKQELLEAQAHVWNHIYSYINSMSLKCAIQLGIPDAIHKHGNPITLSQLADALNINKAKSHGLFRLMRILVHSGFFDKVKVKVKVEGEDEEEEEDAYSLTPASRLLLRSEPLSVAPFALAMSDPVYTETWHHLSEWFRNDAVAAFDTKYGMTFPEYAVADDRLNVLFNEAMACDAGFVNSILTTECREIFDGLESMVDVGGGTGATAKGIAAAFPGMECTVLDLPNVVGGLKGSENLSFVSGDMFDFIPHADAIFMKFILHDWNDEECVKILKKCKEAISRSNNSCRKIILVEIVMEDEKETHEATETKLFFDMQMLAIITGKERSEKEWGKLFFDAGFTNYKITRVLGLRSVIEVFP
Protein: Pheromone alpha factor receptor (D6VTK4)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Receptor for the peptide pheromone alpha factor, the mating factor of yeast.
Subcellular location: Cell membrane {ECO:0000269|PubMed:1330324, ECO:0000269|PubMed:14506226, ECO:0000269|PubMed:16313173, ECO:0000269|PubMed:2017168, ECO:0000269|PubMed:28073700, ECO:0000269|PubMed:2839507, ECO:0000269|PubMed:34627767, ECO:0000269|PubMed:35296853, ECO:0000269|PubMed:7935439}; Multi-pass membrane protein {ECO:0000269|PubMed:11112532, ECO:0000269|PubMed:11467956, ECO:0000269|PubMed:11473349, ECO:0000269|PubMed:1653030, ECO:0000269|PubMed:19383463, ECO:0000269|PubMed:2017168, ECO:0000269|PubMed:35296853}. Note=Internalized after binding of alpha-factor (PubMed:8392878). STE2 enters the cell by receptor-mediated endocytosis and is continuously lost and resynthesized in the presence of alpha-factor (PubMed:1330324, PubMed:3015412, PubMed:7935439, PubMed:8392878). {ECO:0000269|PubMed:1330324, ECO:0000269|PubMed:3015412, ECO:0000269|PubMed:7935439, ECO:0000269|PubMed:8392878}.
Interaction partners:
- Guanine nucleotide-binding protein subunit beta
- Mating factor alpha-1
- Guanine nucleotide-binding protein alpha-1 subunit
- Guanine nucleotide-binding protein subunit gamma
- Pheromone a factor receptor
- Protein SST2
- Mitogen-activated protein kinase FUS3
- Alpha-factor-transporting ATPase
- Protein STE5
- Barrierpepsin
Sequence:
MSDAAPSLSNLFYDPTYNPGQSTINYTSIYGNGSTITFDELQGLVNSTVTQAIMFGVRCGAAALTLIVMWMTSRSRKTPIFIINQVSLFLIILHSALYFKYLLSNYSSVTYALTGFPQFISRGDVHVYGATNIIQVLLVASIETSLVFQIKVIFTGDNFKRIGLMLTSISFTLGIATVTMYFVSAVKGMIVTYNDVSATQDKYFNASTILLASSINFMSFVLVVKLILAIRSRRFLGLKQFDSFHILLIMSCQSLLVPSIIFILAYSLKPNQGTDVLTTVATLLAVLSLPLSSMWATAANNASKTNTITSDFTTSTDRFYPGTLSSFQTDSINNDAKSSLRSRLYDLYPRRKETTSDKHSERTFVSETADDIEKNQFYQLPTPTSSKNTRIGPFADASYKEGEVEPVDMYTPDTAADEEARKFWTEDNNNL
Protein: Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Q501Q9)
Organism: Xenopus laevis (African clawed frog)
Function: Atypical MAPK protein that regulates ciliogenesis by phosphorylating rcsd1 through its binding with dvl2.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:25823377}. Cell projection, cilium {ECO:0000269|PubMed:25823377}. Cell junction {ECO:0000269|PubMed:25823377}.
Interaction partners:
- GST N-terminal domain-containing protein.
- Chloride intracellular channel protein 3
- Protein kinase domain-containing protein
- MGC86479 protein
- protein-tyrosine-phosphatase
- Dual specificity mitogen-activated protein kinase kinase 1
- Protein kinase domain-containing protein
- Uncharacterized protein
- Phospholipase A2.
Sequence:
MSGPEVEDHISQKYDIKKRLGKGAYGIVWKAIDRKSGEIVAVKKIFDAFRNRTDAQRTFREIMFLQEFGEHPNIIKLLNVIRAQNDKDIYLVFEHMETDLHAVIKKGNLLKDIHMRYILYQLLKATKFIHSGNVIHRDQKPSNILLDGDCLVKLCDFGLARSLYQIQEDVGNPALTEYVATRWYRAPEILLASNRYTKGVDMWSVGCILGEMLLGKPLFPGTSTINQIERIMSIIEPPTHEDIVSIKSEYGASVISRMSSKHKVPMAELFPASCPREALDLLSKLLVFNPGKRLTAEEALEHPYVSRFHSPAREPALDYDVILPVDDDIQLSVAEYRNKLYEMILERKMNIRRQKRESLKESVSSSANGAKDRQDTDTSKTPAPPAGTNPAPQPTSSTVPQRAAIAAPNQPPAQKDSTQQSPKIKAPSSNPITHSTTHGSTEDWRTSHNKKAGQQGAAGTTAQEVRKEVESRSRTAPIGRARSFSHSQQARAAATNSALIRKDAPPTGTVSVAAVSARLNQRTAPIQGRDPRSAPRFGRKMFQGKTNVESAGDPKATLHSYTQAYGTISKAALQNLPQQGGAFKGK