wanglab/gogpt-training-data huggingface dataset:
Protein: Papilin (Q5ZR42)
Organism: Caenorhabditis elegans
Interaction partners:
- MEC-5
- Mechanosensory protein 2
- Mechanosensory abnormality protein 6
- AMP-binding domain-containing protein
- Tubulin alpha-3 chain
- Degenerin mec-10
- Degenerin mec-4
- NADP-dependent oxidoreductase domain-containing protein
- Tubulin beta-1 chain
- Mec-8 protein
Sequence:
MHLFLLFIPHVIAVKDLAWYSANPVLSSSHPVGPAAIQAATAIDFCQLPVDTGKCSQQLVRYYYDAAVDECKRFTFSGCGGNSNRFMRRAHCRNRCVKQPNKPEVQELKHRRTVTSTTSTPFQTVNEESTVEPSATKRLPVTLPVKKLELVQVRIFNKTESSFQSGHGNGLCQDCDPLYGTCLDGKCGCMKGFRSLGKVCIDLNECDNGAVCGPNARCVNEIGSFQCVCDAGFSTDGDCKIGQEACMDEFDVNLTEEDCNNGKQEIKYYYDADSVQCKQFFYGGCKTTSRNFFADLQTCDVICVSNQRDYLKSKGQSLSHHPVLEISSDLNNGNDLKSNHYKIDLFSSPSSPVTPNRPLSADDWPLKPITLKPALNLDFSQGKTKSTAEKHKEADDAEILVHQLTPEHNSCDLKFEPVLREECISADWAEKFFWNSEFKDCEPFWYDSSCDPRDRAGKNFFETFEDCKNKCDGVQSQYVVPITTVPDEQSKIEEVETSETPGIVDETTTTAAPEEESEENGFFFKVKPQNYLEDVLSSETEETQHYGFNPNEFLKQNSQNQKPTEITEILRILPAQTEHDEASELKKEDKIEHDILEHLKNKEPTEKVLSTPSTCDLEYDDALRNECTSADWTELYYWNAQFKECEAFWYDSSCGDQDFSKKNLFKNFDDCNNQCVKKIGEALKKMDPETTTTTSTTTTTTTAPTTTKMEEPKRSNYKQSDPLNLILNKALNPDESSELPEKFPPAHEQGFVNFAIKSEVTATTKFDRLKYMAEFRKKLLALPDNFSTTPKQSSPTSSPTTTRMRSPSTHKSTVSQATKTASSTPQSPSTTTSFDDFVEKEKKTVLETIKILDRPEDLCDEPLHPKLEEDCKNDQWEIQWFFNSDRGACKSFWYGGCEIESRNFFPDHANCRHSCAHKYATPASFSSKVYIPPGELSTPVPPRKDRLTTSLKLTYPHSEDLFPSEEHSTVVELDGNFQRTEKQERIRLFPTKTFRPRAPTPTASNIVNVSEGEKTETAPAFYSHIDRVVHDMKTGEHPGYTKPEEFVRRIESASNDYIKYDLQKPDVVTIIDKSPPTVPSRKERTERTEVTTKLPSTRSINDPCDDEYDPKWDEDCLGDTWVVRSYYDSKAEKCKAFWYGGCHTSSRNIWFDKETCRTSCAHKFPTDMPMYGGAQSSEVSAEILPSPQEENSSKETSSSSSSSSSSNTAHISPEHRFKVDLDQKFADVKREHEGREDLAYSQMVQHPVTVSADCLEVYNASLSKPCGDGKSWSNRYFYDKDTRSCRMFWSNGCFSSSKNNFDDLETCQWKCEGRHPQPAGKSCLDKFDERYLEDCRHGEFTNRFYFDHDRKKCVAFHWGGCQSKSQNFFADMTVCQDLCESPPRELTQACLQPFDTTYETSCSAEKPQQYYYFDMSSGICKMFWFGNCKGENQNIFSTLEACQWICERKRDERKPAICADKFDTKYTESCGDSQWTEKWYFDQSSGDCSSFWWDECTSSSQNIFPDEKSCTSNCKHPGFEISSKLATEESKFRCLEPVEIGSCQETYPAFYYDRASRTCRPFAYSGCGGNSNRFMTVSQCENLCFAFNSMNEAEVDCHLPMHIGYGKNEDSCLPQAGFRFYYDRNYGKCSQMWYLGCGGNANNFYSYEICQRTCSQSDVPRELERKTRASSEVCFEPPGDRGICGKNSSTNPLKRWTYGNQKCTSFTYSGCGGNRNRFATQDICENTCNGLMNSNDPRICSFSPDWGSCNQLRYVWFYNLTRGTCDQFLYGGCGGNPNRFDTFEICQKACEVTGTDPCMESLDRGSWCEAMSNRYYFNKRARQCKGFHYTGCGKSGNNFLTKEECQTKCEKRFPRAAPSKKKAKVKLPVGYSGAKPKDKTPMLRHINLNGNNQTYFKSEPQWMDYSSCYGYRYNVTGRDTILNVHYCAIRGSADCISESYRSTEGEEYCNILRPFLRGQNLYSFYFGLDSVNPMYRPKDGLSGRIQRKNETIAAVLVLKANQCHEIC
Protein: Glucosidase 2 subunit alpha (EC 3.2.1.207) (Alpha-glucosidase II subunit alpha) (Glucosidase II gls2) (Glucosidase II subunit alpha) (Q9US55)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalytic subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glucosidase 2 subunit beta
- Probable mannosyl-oligosaccharide glucosidase
- Calnexin homolog
- Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
- UDP-glucose:glycoprotein glucosyltransferase
- Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Uncharacterized protein P4H10.19c
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
Sequence:
MRYHGICWFIFQAAIIFAIFGSCQGAFRHQFKTAEQDGFARRNRDLAKFQKENLNWNGLFQLNSISYNSGVVSGVFEQQSENGENQHLFPFSISFLKNDVVRFQMDEKSRLEGTVEYEKNILTKRRFDASTELGFNERAEVYGKDAHLLEQTSTSLTIRYGSHGRFTVIVTFSPFKVEFQRDGEPQVVLNERHLLNMEYYRPKSSRTPEQEANGMWDETFDNFHDSKPKGPESVGLDIKFVDYGNVYGVPEHTSSLSLKETNNSDAGYTEPYRLYNVDLFEYEVDSPMSQYGAIPFMQAHKPNSDVAVFWSNAAATWIDVEKESGPSPHSQSTSTHWYSESGTLDLFIFLGPKASDVYESYSALVGRPLLPPLFSIGYHQCRWNYVSEEDVLNVDAKFDEVDMPYDTIWLDIEYASKRRYFTWDKATFPNPKAMLEKLDSKSRKLIVILDPHIKNDPNYFVSKELIDYNYAVKDKSGVDNYNADCWPGNSVWVDFFNPEAQAWWGSLYEFDRFESDKNLWIWNDMNEPSVFRGPETSMHRDAIHYGGWEHRDIHNIYGHKCINGTYNGLIKRGEGAVRPFILTRSFFAGTSALAANWIGDTMTTWEHLRGSIPTVLTNGISGMAFSGADVAGFFGNPDAELFVRWYETAIFYPFFRAHAHIDTKRREPWLYGEPYTSLVRELLRIRYRLLPTWYTAFYNSHTHGFPILYPQFLMHPEDEEGFAIDDQFYVGDSGLLVKPVTHPSIDKITIYLADDEVYFDLHDHTEYAGKGHQVVPAPLGRVPVLLRGGNILITRERIRRAAELTRNDPFTLTIAVSKIGKNASGFLYLDDGVTFNYKKGEYLIRHFSYENGILTMKDSHSNPPVSPKYSSSQKHLKVERINIYGEQTRKSIKIRKIIDSEVTEWDVSVDDSGCIRNPQLFLV
Protein: Rhomboid-related protein 1 (EC 3.4.21.105) (Q19821)
Organism: Caenorhabditis elegans
Function: Serine protease which activates lin-3 isoform a in the proximal vulva precursor cells (VPC) during vulva development to transmit the inductive anchor cell signal to the distal VPCs.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MFSSEGKFRKTYRHQFNQLRTGDETEIPMSTLASRIETRKIPLTNGQIHAIKEAPDELVDIDGFQKIVTSKAAQRSTIKRIMYDMADPIMSDSQKIEVHSYIDSYSWCPPPIFMLLITIIQVGIFFFYWESDGGRSIWTDCAGCFVHHNHTAPGIFIFAPKLRGEAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAIDPNSLLVGASAGVYALIFAHVANVILNWHEMPLRWIRVLVLFVFIFLDFGGAIHRRFYTNDCDSVSHLAHIAGAVTGLFFGYVVLYNVVEHRIEKIIRYVCLFLYSAFFATTIIFVIVRQPYSKNLWNNENCS
Protein: Transmembrane protein (O53788)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MKWNTVAASLAAGVITIAVALAAPPPAAHAKNGDTHVTGQGIERTLDCNESTLLVNGTQNIVTALGTCWAVTVMGSSNTVVADTIINDITVYGWDETVFFRNGDPFIWDRGRELGMVNRLQRVG
Protein: Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1) (Q64279)
Organism: Mus musculus (Mouse)
Function: Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box). Acts as a transcriptional repressor of SOX15. In the adult, could be required for ongoing expression of cardiac-specific genes (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:17891141}. Nucleus, nucleolus {ECO:0000269|PubMed:17891141}. Note=Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity.
Interaction partners:
- Transcription factor GATA-4
- Homeobox protein Nkx-2.5
- Transcription factor E2-alpha
Sequence:
MNLVGSYAHHHHHHHSHPPHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVAAAAYGPDARPSQSPGRLEALGSRLPKRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKTDGGRESKRKRELPQQPESFPPASGPGEKRIKGRTGWPQQVWALELNQ
Protein: Nuclear receptor-interacting protein 2 (Q9BQI9)
Organism: Homo sapiens (Human)
Function: Down-regulates transcriptional activation by nuclear receptors such as NR1F2.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MLFIFPLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQVEQLELQLGQETVVCSAQVVDAESPEFCLGLQTLLSLKCCIDLEHGVLRLKAPFSELPFLPLYQEPGQ
Protein: AP-1-like transcription factor YAP6 (Q03935)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcription activator involved in the regulation of genes expressed in response to environmental changes and metabolic requirements. According to genome-wide promoter binding and gene expression studies it regulates, among others, genes involved in ribosome biogenesis, protein synthesis, carbohydrate metabolism, and carbohydrate transport. It may also be involved in pleiotropic drug resistance. When overexpressed, it confers resistance to cisplatin, methylmethanosulfonate, and mitomycin C, and increases cellular tolerance to sodium and lithium.
Subcellular location: Nucleus {ECO:0000269|PubMed:11179441}.
Interaction partners:
- Protein SOK2
- Putative transcription factor PHD1
- Repressor ROX1
- Transcription factor SKN7
- AP-1-like transcription factor YAP5
- CRE-binding bZIP protein SKO1
- Homeobox protein CUP9
- AP-1-like transcription factor YAP7
- General transcriptional corepressor CYC8
- Zinc finger protein MSN4
Sequence:
MQNPPLIRPDMYNQGSSSMATYNASEKNLNEHPSPQIAQPSTSQKLPYRINPTTTNGDTDISVNSNPIQPPLPNLMHLSGPSDYRSMHQSPIHPSYIIPPHSNERKQSASYNRPQNAHVSIQPSVVFPPKSYSISYAPYQINPPLPNGLPNQSISLNKEYIAEEQLSTLPSRNTSVTTAPPSFQNSADTAKNSADNNDNNDNVTKPVPDKDTQLISSSGKTLRNTRRAAQNRTAQKAFRQRKEKYIKNLEQKSKIFDDLLAENNNFKSLNDSLRNDNNILIAQHEAIRNAITMLRSEYDVLCNENNMLKNENSIIKNEHNMSRNENENLKLENKRFHAEYIRMIEDIENTKRKEQEQRDEIEQLKKKIRSLEEIVGRHSDSAT
Protein: NPC intracellular cholesterol transporter 1 (A0A8I6AL97)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MVFSQSCVWYGECGVAFGDKRYNCEYSGPPKPLPKDGYDLVQELCPGLFFGNVSLCCDVQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPETRENKTNVKELEYYVGRSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSVLGMEPMRNATKGCNESVDEVTGPCSCQDCSAVCGPKPQPPPPPVPWRILGLDAMYVIMWVAYMAFLVLFFGGLLAVWCHRRRYFVSEYTPIDSNIAFSSNSSDKGEASCCDPLGVAFDDCLRRMFTKWGAFCVRNPTCIIFFSLVFIAACSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHIYEPYPSGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDNQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAWAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVLISYAVMFLYISLALGHIQSWNRVLVDSKISLGIAGILIVLSSVTCSLGIFSYIGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSFLGLDIKRQEKNRLDILCCVRGPDDGQESQASESYLFRFFKNAFAPFLLTDWLRPVVMAVFVGILSFSIAVVNKVEIGLDQSLSMPNDSYVIDYFKSLGQYLHSGPPVYFVLEEGYNYSSRRGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNASVIDPTCVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNIMGDDTYIGATYFMTYHTILKTSADYIDALKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDAIFNLSVSLGSIFLVTLVALGCELWSAVIMCLTIAMILVNMFGVMWLWGISLNAVSLVNLVMTCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKRHTTQERYKGTERERLLNF
Protein: Gastrin/cholecystokinin type B receptor (Cholecystokinin-2 receptor) (Q1M2P7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MDLATTPSSSTLAPAVTVRAPGNRSVVRVSADVPIWVVPCYSAILLCAVVGNLLVVLTLVKNRRMRTITNVFLLNLAISDILLGVFCMPVTLVGTLLRHFIFGELLCKLIQFAQAASVAVSSWTLVAISCERYYAICHPLRSRTWQTINHANKIIAIIWLGSLVCMTPIAAFSQLMPTSRPGLRKCREQWPADSLNYERAYNLFLDLALLVLPLLALSFTYLFITRTLYVSMRNERAMNLGSSGPEVTTSSSAAVAEAGSQRRANGSHCQSLDTIVPHQHNPHQQHHHHSQYYYDYGHCGSKRRLISGGGPCEGRRHLYCMRSASVKSLRHQQINGGGGTLSGTGAGNGECCSRVHRMRQQMQLQQQGYVSDNESRRKSLSQPSLRITEAGLRRSNETKSLESKKRVVKMLFVLVLEFFICWTPLYVINTMTMLLGPTVYEYVGYTSISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFKGMRVCERLCAPCCFWRRRSKNETNLSVAGNSIALANSVMSSHTILESPRL
Protein: IP17403p (Transmembrane endosomal protein, isoform C) (Transmembrane endosomal protein, isoform D) (A1A714)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Autophagy-related 8a, isoform A
- Autophagy-related 8b, isoform A
Sequence:
MSTTAASLIEAALNASSGNATATTAGSLEATGKPNYVVQVKNTPMSTPLDPLLHVGDGIFLQTKTAQVLAGVCVWAALFITCQQIYQHLRWYTNPQEQRWIVRILFIVPIYATYSWISLLFFNSDNVYIYFFTVRDCYEAFVIYNFLSLCYEYLGGEGNIMSEIRGKPIKTSCLYGTCCLKGKTYTIGFLRFCKQATLQFCLVKPLVAFIIIFLQAFGHYHDGDWSADGGYIYITIIYNISVSLALYGLYLFYFATRDLLTPFEPVLKFCTIKSVIFLSFWQGVGLAILEKANVISPIVDSAGTVTVEPGTVSAGYQNFFICIEMLFAAIALRYAFPYQVYARSCISDGHGRSVTMQSISSSLKETMNPKDIMTDAIHNFHPQYQQYTQYSSGGKNSRGIRVSSYDPDDPSSGAAAGGMQASQPTSGGYDAVATGPGSGGNGGSNCMASKTLGNQRKFQPGGQRVATISQNYNEKTMLLSSDDEYQ
Protein: Aspartic protease 3 (TgASP3) (EC 3.4.23.-) (Toxomepsin 3) (Q6J6C2)
Organism: Toxoplasma gondii
Function: Required for the processing-mediated maturation of a subset of microneme proteins, such as MIC6, and rhoptry proteins, such as ROP1. By regulating microneme and rhoptry processing, plays an essential role in the lysis of the host cell membrane during egress and in rhoptry content discharge, which is required for invasion of host cells.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:28898199}. Note=Localizes to a post-Golgi compartment and an endosome-like compartment in the secretory pathway. {ECO:0000269|PubMed:28898199}.
Interaction partners:
Sequence:
MEGRTTAGRATPAGFWLFSCCLASVLWSANALIPAGKSAGSSFLAATSSQSSEEAPREFPGHLSNSQIASETGSALKIEEIASSGSAPEVSGAAGASASKTSEKPIRPYHTGPSSRSSAYSASSGIPLCHTCSSFDAANGGCRLCVHGEVASDFLMPMMPIRNIDTHREETLSRLEANHRTHLNEKKNFYVLRGKGPFGSLGNLPGTPGLDAAIAFGLSSPDLPSASFAQIKNKDSSDSGDVAAVGEETDSAVADGSKTLDLDLKLAETSVPILQMKDSQYVGVIGIGTPPQFVQPIFDTGSTNLWVVGSKCTDDTCTKVTRFDPSASKTFRAANPPVHLDITFGTGRIEGSTGIDDFTVGPFLVKGQSFGLVESEGGHNMHGNIFKTINFEGIVGLAFPEMSSTGTVPIYDNIISQGTLKENEFAFYMAKGSQVSALFFGGVDPRFYEAPIHMFPVTREHYWETSLDAIYIGDKKFCCEEGTKNYVILDSGTSFNTMPSGELGKLLDMIPSKECNLDDPEFTSDFPTITYVIGGVKFPLTPEQYLVRSKKNECKPAYMQIDVPSQFGHAYILGSVAFMRHYYTVFRRSDGTRPSLVGIARAVHNDDNSAYLSNVLNEYPGAHIRKEDLMMERSMSAPSMREL
Protein: Euchromatic histone lysine N-mthyltransferase EHMT2/G9a (Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.354)) (A8TT22)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
Sequence:
MSAAERALENPSDGSSSQSSHEVEVNPAVKGKQMEDLTGRQDDGRPSTSTKTFTASGRAKMSVCGPGSKTPSSSSSSSSSSSAGPPAKVHRARKTMNRPPLPQIKPVESVSPAAAEKPAGEEKPDADTVVKKRKAGLDVSATPSGAPEKVLKPQTEPPMTASPAVGKAEPVAAATKDSHSRWMEDLDEEADEEDFHLLYNSYCGDDVIYSDSKSDEGMTEEPMGAGHLSDHSSSSDPPLPAYKRNSSEREENTWKRQGKGKARDRAAAGGEQDTEKGAESASVAVGSTDYTEVPLDSLDISAADSLSHADISAADSLSHADGSDAETERLEELPLCSCRMEAPRLDSSSVRSSRTCMAIQSINGELVGCTNVIMKGETMRPSSRVSLMVLCETHRSHMVKHHCCPGCGYFCLSGTFLECCPDVHITHRFHRGCVSVLGSGRSRGAAGGSDDQWAEPTSSGRSRGTVGVGLLFCPHCGEDASEARTVSIPPEAPPAGSHVVTASASSTTASNHTQHTPQTHRRTTDNLNARMRCHGDARKGAELQSQPTNGAAPGSGEEDVVAVGDGGVDSVGPSLVLPNGKPVCPSALPAGDRRAALQRAILTQDSERRKKLRFHPRQLYPAAKQGEAQRVLLMLMEGMDPSYQSDSQNRRCALHAAAQRGLLEICYLLVQAGAKVDAQDKSLRTPLLEAIVNNHVDVVKYLIQSGACVYHAEDDGSTGLHHAAKLGNLEVVMLLLSTGQVDINAQDSGGWTPVIWAAEHRHIEVIRALLNRGADVTLRDKEMNVCLHWASFAGSAEIAELVLNAGCPLSSVNVHGDTPLHISAREGYSDCVTLFLSRGADIDIVNKEGDTPLSLARGETPVWVALQINRKLRRGIANRIVRTERIICSDVAQGYENVPIPCVNGVDDEGCPSDYKYIAENCETSAMNIDRNITHLQHCSCTDDCSSSNCLCGQLSIRCWYDKDHRLLQEFNKIEPPLIFECNMACSCHKTCKNRVVQAGIKVRLQLYRTEKMGWGVRALQDIPQGSFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIFTGQELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLEVCVEPDTALSLIGHS
Protein: Calcium-dependent protein kinase 24 (EC 2.7.11.1) (Q9SIQ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Putative proline-rich receptor-like protein kinase PERK6
- Uncharacterized protein At4g13230
- Potassium channel AKT6
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- Exopolygalacturonase clone GBGA483
- Protein RALF-like 4
- Cytochrome P450, family 702, subfamily A, polypeptide 8
- non-specific serine/threonine protein kinase
- Exopolygalacturonase clone GBGE184
Sequence:
MGSCVSSPLKGSPFGKRPVRRRHSSNSRTSSVPRFDSSTNLSRRLIFQPPSRVLPEPIGDGIHLKYDLGKELGRGEFGVTHECIEISTRERFACKRISKEKLRTEIDVEDVRREVEIMRCLPKHPNIVSFKEAFEDKDAVYLVMEICEGGELFDRIVSRGHYTERAAASVAKTILEVVKVCHEHGVIHRDLKPENFLFSNGTETAQLKAIDFGLSIFFKPAQRFNEIVGSPYYMAPEVLRRNYGPEIDVWSAGVILYILLCGVPPFWAETEEGIAHAIVRGNIDFERDPWPKVSHEAKELVKNMLDANPYSRLTVQEVLEHPWIRNAERAPNVNLGDNVRTKIQQFLLMNRFKKKVLRIVADNLPNEEIAAIVQMFQTMDTDKNGHLTFEELRDGLKKIGQVVPDGDVKMLMDAADTDGNGMLSCDEFVTLSIHLKRMGCDEHLQEAFKYFDKNGNGFIELDELKVALCDDKLGHANGNDQWIKDIFFDVDLNKDGRISFDEFKAMMKSGTDWKMASRQYSRALLNALSIKMFKEDFGDNGPKSHSMEFPIARKRAKLLDAPKNKSMELQISKTYKPSGLRN
Protein: Uncharacterized amino-acid permease C965.11c (O59831)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized amino-acid permease C11D3.08c
- Uncharacterized amino-acid permease C15C4.04c
- Ribose-phosphate pyrophosphokinase 1
- Vacuolar membrane amino acid uptake transporter fnx2
Sequence:
MEAAPSEKVPAKKLSSSENLDIGVSEVVTVDAAENNSNGIKRGLKTRHVSMMALAGIIGPGVFIGMGSALHIGGPVGLIVGFAIVSIVVFGVMLSIGEFNSLFDFNFNTHAARWVDPAFGAAIGWNYVIVWLTNIAAEYTSLTSILQYWGPHVPSYGFFLIFWGFFTCYQMLGVSVFGESEYILAFIKLLFITGFYIFAIIYAAGGIPHHKPPNLFKEMPLAHGFGGIVSAFVYAGVFFSGVESVSMTAAESKNPKKAIPLAVRQTFWRILYVYFGISISYGITVAWNDPNLSSGSKTLKSPMTIAIMNAGWNHAGDFVNAVILITCLSSINSGIYIGSRSLYNLAKDGMAPKIFKRVDKRGVPWVAVHSVHLFGFLSIMNYSTGAVKAYGYIINLAGVSAFIVWTAIIFVHFRFRRGWVKQGYALSDLPFKSPLYPFPQLIGFVIGIILTLVQGWTVFKPFAAGDFVDAYILLPLFFVIWLSYKFIKKTKWVSYEDMDFINGRRVIEPTYSNEQSSDKETEDGKKTSFWNRVWKEV
Protein: Aspartate-beta-hydroxylase (A0A8I6GIW1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Sarcoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004157}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004157}.
Interaction partners:
Sequence:
MAEDKEAKHGGHKNGRRGGISGGSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLDLEADGPAGEPQSEVEDFLTATDSDDRFEALEPGTVHEDTEDSYHVEETASQNHPNDAEEVMSEQESSDHGEAVTDDGLQQHAEEVRHEDYDEPVYEPSENERIEISDNAIDDSNIISEEINVASVEEQQDTPPDT
Protein: RING-type domain-containing protein (O01482)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSEKNTENPEILSTVLAGYCQCQVCYQPFNETTKLARSLHCGHTFCTECIRNVQNYGNSPHLECPTCRAETKSNIENVAPNFSIMELARNFGLLGPPVDAPRTSSSCCSNKTNRDEMIDNKFRELLVEVKSSLIHHFDVFRIKSQLWSLAEAEREVSNMAEALAGAVSECYYDSDDNSDANSEDQRVRTMLRFLAARDSDSETTEDSTDFLESNTTVPDRTLGGGFYRNFRRLFGDENELDDPGVVSGIEEAAAYRRFRGLFGNDNDSISQVSTTSGSFGNHENDHFCPFSDDDNISECSDDYYPTLVMPETDEEETYKSFRCLFGDENGNLDFSDDEKEFSDNESSLSSVSTEDFPNSHIEEAGRVLHRFLLLSALLNEE
Protein: Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (Zeta-crystallin) (P96826)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Putative short-chain type dehydrogenase/reductase Rv0148
- Aldehyde dehydrogenase
- 3-hydroxyacyl-thioester dehydratase Z
Sequence:
MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGEYQLKLTPPFVPGMETAGVVRSAPSDAGFHVGERVSAFGVLGGYAEQIAVPVANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAAGGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQVRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIGFAAGAVPTLKVNRLLVRNISVVGVGWGEYLNAVPGSAALFAWGLNQLVFLGLRPPPPQRYPLSEAQAALQSLDDGGVLGKVVLEP
Protein: MIP16350p (Something that sticks like glue, isoform B) (D5SHU1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSVHYKFKSTLNFDTITFDGLHISVGDLKREIVQQKRLGKIIDFDLQITNAQSKEEYKDDGFLIPKNTTLIISRIPIAHPTKKGWEPPAAENAFSAAPAKQDNFNMDLSKMQGTEEDKIQAMMMQSTVDYDPKTYHRIKGQSQVGEVPASYRCNKCKKSGHWIKNCPFVGGKDQQEVKRNTGIPRSFRDKPDAAENESADFVLPAVQNQEIPEDLICGICRDIFVDAVMIPCCGSSFCDDCVRTSLLESEDSECPDCKEKNCSPGSLIPNRFLRNSVNAFKNETGYNKSAAKPAAVKNEEKPPVEKEVEKKPVAEVEPEETEVKPEKQKESETNGSNPPKSESPEPPATTEPSQKEKDKYDSDYEDNITIKMPQPAADSTTVPSKRSPSYSHRSESSHRRDRSDYVSDHDHKHQRPSKSESVNKDRSLLPLPIGTLPSYQGHMMAESEEARRSSAYKPPYMQMQRGPPPMHMMSHHMPAYNNGFNNMGQRPPLR
Protein: Uncharacterized protein YciO (P0AFR4)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized protein YciQ
- 5'-3' exoribonuclease Rnm
- Ribosomal large subunit pseudouridine synthase B
- Putative transport protein YbjL
Sequence:
MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKIEDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILKGTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEIKDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL
Protein: Proprotein convertase subtilisin/kexin type 9 (Proprotein convertase 9) (Subtilisin/kexin-like protease PC9) (E7F2J6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell surface {ECO:0000256|ARBA:ARBA00004241}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}. Endosome {ECO:0000256|ARBA:ARBA00004177}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. Lysosome {ECO:0000256|ARBA:ARBA00004371}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Very low-density lipoprotein receptor
- Apolipoprotein Ba.
- Low density lipoprotein receptor
- Apolipoprotein E receptor 2
- Sterol regulatory element-binding protein 2
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
- Apolipoprotein Eb
- 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Sequence:
MRSVVSVCCLGFLLGLLAVVECDEDYIEDEDEMILSLILQDDTQPEAENRPSAQFYRCTKDAWRMPGQYLVVMRNGTHVNQVERTTRRLSAKAAKRGYLIEILQTYSGAFRGFLVKMSSDVLHMAVKLPHVEYIEEDSSIFAQSIPWNLQRVLQNKHEAGKYSPPNDGAKVGVYLLDTSVQLTHREVEDRVMVTDFNRVPEEDGVRVHRQASQCDSHGTHIAGVISGRDSGVARGASVNSVRVLNCQGKGTVSGALAGLEYIQSSLASQPVSPVILLLPFVGGFSRTLNTACRKIVESGAVLIAAAGNYNDDACLYSPASEPEVITVGAVNFADQPLNRGTTGTNVGRCVDVFAPGDDIISASSDCPTCFTTKSGTSQAAAHVAGVAAVLLNLRPNSSSAEVLQQLRYHSVKQVINPESLPVMHRLTTPNMVVALPDPTSTLTGEDLLCRSVWSERSASPVFSTAVSRCRSTEEMLSCSSFSDNGMRAGERVEERDGQKECVAVNVNGGPGVFAVARCCTGHRAQCQMLEGPERGAGAECPPEHHLTGCSFSSSSGEASDSDRTLHGSRRTCAAKKGMMSYAFCCHTSTLECRLKEHHLNTLSQQVEVSCEDSWTLTACEALSRDAVIHGAFAMGNTCVVRTSGVDKDAAAIATCCRNHPLHGTQDH
Protein: MNAT1 component of CDK activating kinase (A0A8I5ZV40)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLENTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQESEQRRLFIQKEEELQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKSMKPVTFSTGIKMGSLVLIVYLKESFQDYAFKFLSNFYSKVNGLDI
Protein: Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1) (mTrp1) (Trp-related protein 1) (Q61056)
Organism: Mus musculus (Mouse)
Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P48995}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Stromal interaction molecule 1
- Short transient receptor potential channel 5
- Short transient receptor potential channel 4
- Transient receptor potential cation channel subfamily V member 4
- Polycystin-2
- Voltage-dependent T-type calcium channel subunit alpha-1H
- Voltage-dependent T-type calcium channel subunit alpha
- Short transient receptor potential channel 3
- Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1
- Bone morphogenetic protein receptor type-2
Sequence:
MMAALYPSTDLSGVSSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENESLDILQLLLDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN