wanglab/gogpt-training-data huggingface dataset:
Protein: Type II secretion system protein L (T2SS protein L) (Cholera toxin secretion protein EpsL) (General secretion pathway protein L) (P45782)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Function: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Plays a role in the complex assembly and recruits EpsM resulting in a stable complex in the inner membrane. Provides thus a link between the energy-providing EpsE protein in the cytoplasm and the rest of the T2SS machinery.
Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:P25060}; Single-pass membrane protein {ECO:0000250|UniProtKB:P25060}.
Interaction partners:
- Type II secretion system protein M
- Type II secretion system ATPase E
- Type II secretion system protein N
- Type II secretion system protein J
- Type II secretion system protein K
- Type II secretion system protein H
- Type II secretion system core protein G
- Type II secretion system protein I
- Type II secretion system protein C
- MSHA biogenesis protein MshJ
Sequence:
MEGSVSEFLTVRLSSQKEADIPWLVWSAEQQEVIASGQVAGWEALHEIESYADQRSVVVLLAASDLILTSVEIPPGASRQLENMLPYLLEDEIAQDVEDVHFCVLSKGRETADVVGVDRLWLRACLDHLKACGFDVKRVLPDVLAIPRPEHGLAALQLGDEWLVRKSTTQGMAVDAQWLSLLAASDWVQNEGEYLPLQALTPLPELSLAETQEWRYEPSGLVMQLLTQEALTSKFNLLTGSFKLKSSWLRYWQIWRKVAIAAGLFVAVSISYSLFQAHQYEAQADAYRAESERIFRSIFPDKQKIPTVTYLKRQMSDEMARLSGGASVGSVLKWLSPLPEALKGVNLQLQSIKFDSNRSEIRLEATSRDFQSFEQARTQLEQYFAVEQGQLNKNGEQVFGVFVVKPK
Protein: CXXC motif containing zinc binding protein (UPF0587 protein C1orf123) (Q9NWV4)
Organism: Homo sapiens (Human)
Interaction partners:
- Putative GTP-binding protein 6
Sequence:
MGKIALQLKATLENITNLRPVGEDFRWYLKMKCGNCGEISDKWQYIRLMDSVALKGGRGSASMVQKCKLCARENSIEILSSTIKPYNAEDNENFKTIVEFECRGLEPVDFQPQAGFAAEGVESGTAFSDINLQEKDWTDYDEKAQESVGIYEVTHQFVKC
Protein: Aromatic-amino-acid aminotransferase (EC 2.6.1.57) (P43336)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cytoplasm.
Interaction partners:
- Phenylalanine-4-hydroxylase
- Pterin-4-alpha-carbinolamine dehydratase
- 4-hydroxyphenylpyruvate dioxygenase
- 3-dehydroshikimate dehydratase
- Maleylacetoacetate isomerase
- Histidinol-phosphate aminotransferase 2
- Probable aminotransferase
- fumarylacetoacetase
- Bifunctional chorismate mutase/prephenate dehydratase
- Monofunctional chorismate mutase
Sequence:
MSHFAKVARVPGDPILGLLDAYRNDPRADKLDLGVGVYKDAQGLTPILRSVKLAEQRLVEQETTKSYVGGHGDALFAARLAELALGAASPLLLEQRADATQTPGGTGALRLAGDFIAHCLPGRGIWLSDPTWPIHETLFAAAGLKVSHYPYVSADNRLDVEAMLAGLERIPQGDVVLLHACCHNPTGFDLSHDDWRRVLDVVRRRELLPLIDFAYQGFGDGLEEDAWAVRLFAGELPEVLVTSSCSKNFGLYRDRVGALIVCAQNAEKLTDLRSQLAFLARNLWSTPPAHGAEVVAAILGDSELKGLWQEEVEGMRSRIASLRIGLVEALAPHGLAERFAHVGAQRGMFSYTGLSPQQVARLRDEHAVYLVSSGRANVAGLDARRLDRLAQAIAQVCAD
Protein: Transcription factor bHLH11 (Basic helix-loop-helix protein 11) (AtbHLH11) (bHLH 11) (Transcription factor EN 137) (bHLH transcription factor bHLH011) (Q8W2F2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Probable nicotianamine synthase 4
- Transcription factor bHLH100
- Transcription factor bHLH101
- Transcription factor ORG3
- Transcription factor ORG2
- Protein ZINC INDUCED FACILITATOR 1
- Ferric reduction oxidase 2
- Ferric reduction oxidase 3, mitochondrial
- Fe
- Transcription factor bHLH18
Sequence:
MDQPMKPKTCSESDFADDSSASSSSSSGQNLRGAEMVVEVKKEAVCSQKAEREKLRRDKLKEQFLELGNALDPNRPKSDKASVLTDTIQMLKDVMNQVDRLKAEYETLSQESRELIQEKSELREEKATLKSDIEILNAQYQHRIKTMVPWVPHYSYHIPFVAITQGQSSFIPYSASVNPLTEQQASVQQHSSSSADASMKQDSKIKPLDLDLMMNSNHSGQGNDQKDDVRLKLELKIHASSLAQQDVSGKEKKVSLTTTASSSNSYSLSQAVQDSSPGTVNDMLKP
Protein: Response regulator protein (I3NI96)
Organism: Yersinia pseudotuberculosis serotype I (strain IP32953)
Interaction partners:
Sequence:
MRVLVVEDNALLRHHLTVQMREMGHQVDAAEDAKEADYFLQEHAPDIAIIDLGLPGEDGLSLIRRWRSHQENLPILVLTARESWQDKVAVLEAGADDYVTKPFHLEEVIARMQALMRRNIGLASQIIELPPFQIDLSRRELCVNQQQIKLTAFEYTIIETLIRNAGKVVSKDTLMLQLYPDAELRESHTIDVLMGRLRKKLLAEHQGEVITTIRGQGYRFDVN
Protein: Estrogen receptor (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) (Q14267)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGDEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSK
Protein: Chchd3 protein (Q91VG6)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00034476}; Lipid-anchor {ECO:0000256|ARBA:ARBA00034476}.
Interaction partners:
Sequence:
KESSPSGSKSQRYSSVYGASVSDEDLKRRVAEELALEQAKKESEHQRRLKQARDLERERAAANEQLTRAVLRERISSEEERMKAKHLARQLEEKDRVMRKQDAFYKEQLARLEERSSEFYKVTTEEYQKAAEEVEAKFKRYEYHPVCADLQTKILQCYRQNTQQTLSCSALASQYMHCVNHAKQSMLEKGG
Protein: Splicing factor 1, isoform C (A0A0B4KGU8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSATPPDLLSLAASREVSAAVAVAASANGGSGRSADKERSRSRDRGRDKDKDRDKDRKKRDKDSRDRDSRRRDDRGDRDRDRERDRDSRSHRSKSRNYDDGDRRRKRSRSRDRDRDRKRDRDRDSRSRRSSSRGGRDDYDRSRRRRSRSRSYERRRNDRGSQRDQRDQHSQRSSRERTHVNPFDTSNSRNSLNQDHDQSRIPSLFDRQQGLETIREEGREQRFDLTQTIQELMGNAGGNKGFASFFNSQNSNDSTSNGAFDNSADSAAERKRKRKSRWGGSENDKTFIPGMPTILPSTLDPAQQEAYLDRPRRSPFIVLMASG
Protein: Protein FAM210B, mitochondrial (Q96KR6)
Organism: Homo sapiens (Human)
Function: Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:26968549}. Mitochondrion outer membrane {ECO:0000269|PubMed:28594398}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAGLLALLGPAGRVGARVRPRATWLLGATAPCAPPPLALALLPPRLDARLLRTARGDCRGHQDPSQATGTTGSSVSCTEEKKQSKSQQLKKIFQEYGTVGVSLHIGISLISLGIFYMVVSSGVDMPAILLKLGFKESLVQSKMAAGTSTFVVAYAIHKLFAPVRISITLVSVPLIVRYFRKVGFFKPPAAKP
Protein: Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (SMG p25A GDI) (P21856)
Organism: Bos taurus (Bovine)
Function: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Subcellular location: Cytoplasm {ECO:0000250}. Golgi apparatus, trans-Golgi network {ECO:0000250}.
Interaction partners:
- Ras-related protein Rab-3A
- small monomeric GTPase
- Ras-related protein Rab-8A
- Ras-related protein Rab-1B
- Ras-related protein Rab-5A
- small monomeric GTPase
- Ras-related protein Rab-35
- small monomeric GTPase
- Ras-related protein Rab-6B
- small monomeric GTPase
Sequence:
MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEADQ
Protein: Anion exchanger SLC26A3 (Solute carrier family 26 member 3) (B6DUH7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Glucose-6-phosphate exchanger SLC37A1
- Sodium/hydrogen exchanger
- Cystic fibrosis transmembrane conductance regulator
Sequence:
MQPFGRHYVVVRPLFSEDSFAEQHERINRKRKTLRHHLKDYFSGVSFSKLCLCCSCDAKRAKNAALSLFPFIGWMKDYKIKEWLLGDIVSGISTGLVAVLQGLAFSLLASLPPGYGLYTAFFPAIIYFFLGTSRHLSVGAFPILSLMVGAVVTRLVPDEGPSFNITGFEGLSLEQQRVLVASSVTFLMGAFQLVMGLLQVGFIVMYLSETLVSGFTTAAAVHILVSQLRFVLGLDFPGINGPLAIIYTLVEVFSRITSTNVADLVTSIAIMALVLIVKEINDRFKSKLPVPIPIEVIMTVIACGVSYAFNFEERFDVVIVGEMVNGYESPVAPNLEVIEETAVEAFPMAIVGFAVAFSVAKVYSVKHDYTIDGNQELIAFGVSNMFGASFRSFAASTALSRTAIQESTGGKTQIAGILSAMMVLIVIVGVGFLLEPLPRSVLGALVIVNLKGMLMQFSELPFLWRNDRPDFVTWMVTFMASLFLGLDLGLAVGIGAELFTVVYRTQFPRCSVLANISGTDLYRDRKDYTSIYEPDGVKIFKIPSPIFFANIDFFRDKLVQEVGFNPMRVLKKRNKALRKIRKMLCNGELEVSDRGPVLRQPSVDTSEGSMEDLDQPIDFSDLPIQVNWNSQLPANISVPPVNIHSLILDFCAVSFIDVSALKGLKATLKEFIRIEVDVYIVSCDVYIMEKLQHCTFFDDEIKTSIFYPTLHDAMLHILETHPDHGELEKDININYEVIQRDSLTV
Protein: Tyrosine-protein kinase receptor (EC 2.7.10.1) (Q9PWN6)
Organism: Gallus gallus (Chicken)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
NIAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLHLIRGETLEAGNYSFYALDNQNLRQLWDWSKHNLTIARGKLFFHYNPKLCLSEIHKMEEISGTKGRQERNDIALKTNGDQASCENELLKFSSIRTSHDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDVDPPPRSNEPKAQAQPGWLLRGLKPWTQYAVFVKTLVTFSDERRTYGAKSEIIYVQTNATVPSVPLDPISVSNSSSQIILKWKPPSEPNGNITHYLVYWQQQAEDSELYELDYCLKGLKLPSRTWSPPFESEDPQKYNQSESEDVSGECCSCPKTDSQIQKELEESAFRKTFENYLHNEVFVPRPSRKRRDLGSIANATVVIPTIPSSPNSSAAASESAEEQKPFEKVKFKESLVISGLRHFTGYRIELHACNHDAQESRCSVAAYVSARTMPEAKADDIVGPVTHELVEKNTVHLKWQEPKEPNGLIVLYEVNYGRLGEAEEAHFCVSRKHFASEQGCKLRGLQPGNYSVRIRATSLAGNGSWTEPTYFYVADYLNAQPNIAVIIVPIIFAIIIAGIIGAAYVLVKKRQTEGPTGPLYASSNPEYLSASDVYVPDEWEVPREKITLLRELGQGSFGMVYEGIAKDIVKGELETRVAVKTVNESASLRERIEFLNEASVMKGFICHHVVRLLGVVSKGQPTLVVMELMAHGDFKSYLRSLRPDAENNPGRPPPTLREMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTYSDVWSFGVVLWEISSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERLHNLMQMCWQYNPKMRPTFIEVIEMLKEDLHPSFQEVSFFYSEENKPLETEEYEMDFENMESIPLDPSSYTQRDKALGRDNGPSMALKGNYEEHIPYTHMNGGKKDGRILSMPRSSPS
Protein: Latent nuclear antigen (Q9DUM3)
Organism: Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Interaction partners:
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVASIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSSGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEDEEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELDEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
Protein: Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) (Q6P2H3)
Organism: Homo sapiens (Human)
Function: Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:26220856}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:26220856}. Nucleus, nucleolus {ECO:0000269|PubMed:21399614}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:29712910, ECO:0000269|PubMed:32107292}. Cytoplasm, cell cortex {ECO:0000269|PubMed:32107292}. Note=Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856). Localizes at the leading edge (PubMed:32107292). {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:26220856, ECO:0000269|PubMed:32107292}.
Interaction partners:
- Transcription factor SOX-13
- Centrosomal protein of 192 kDa
- SCL-interrupting locus protein
- Transcription factor SOX-5
- Serine/threonine-protein kinase PLK4
Sequence:
MAMQEKYPTEGISHVTSPSSDVIQKGSSLGTEWQTPVISEPFRSRFSRCSSVADSGDTAIGTSCSDIAEDFCSSSGSPPFQPIKSHVTIPTAHVMPSTLGTSPAKPNSTPVGPSSSKLPLSGLAESVGMTRNGDLGAMKHSPGLSRDLMYFSGATGENGIEQSWFPAVGHERQEEARKFDIPSMESTLNQSAMMETLYSDPHHRVRFHNPRTSTSKELYRVLPEAKKAPGSGAVFERNGPHSNSSGVLPLGLQPAPGLSKPLPSQVWQPSPDTWHPREQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSPPSPDTAQLALELHQELASCLQDLQAVCSIVTQRAQGHDPNLSLLLGIHSAQHPETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTTMSDRYAQDMGENCVTQ
Protein: Collagen alpha 1(XIV) chain (Q7M2W9)
Organism: Bos taurus (Bovine)
Interaction partners:
Sequence:
CCELPALRDEEACPELPHADGSSGPPGPPGPIGIPGAPGVPGVTGSMGPQGALGPPGVPGAGDLQSQAMVRQVCEQLIQSHTIQGPPGEPGRPGSPGTPGEQGPPGAPGFPGNAGVPGSXGERGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQPGYCDPSSCSAY
Protein: Repulsive guidance molecule B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON) (Q6NW40)
Organism: Homo sapiens (Human)
Function: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q7TQ33}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q7TQ33}. Membrane raft {ECO:0000250|UniProtKB:Q7TQ33}.
Interaction partners:
- Neogenin
- Bone morphogenetic protein 2
- Programmed cell death 1 ligand 2
- Bone morphogenetic protein receptor type-1B
- Bone morphogenetic protein receptor type-1A
- Activin receptor type-1
- Netrin-1
- Growth/differentiation factor 5
- Repulsive guidance molecule A
- Dorsal root ganglia homeobox protein
Sequence:
MGLRAAPSSAAAAAAEVEQRRSPGLCPPPLELLLLLLFSLGLLHAGDCQQPAQCRIQKCTTDFVSLTSHLNSAVDGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTSSTNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNFQTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDDLPAAFVDGTTSGGDSDAKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPEDLAMSYEESQDLQLCVNGCPLSERIDDGQGQVSAILGHSLPRTSLVQAWPGYTLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFPSSGNGTPRGGSDLSVSLGLTCLILIVFL
Protein: Uncharacterized protein C3D6.13c (P87178)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative protein disulfide-isomerase C1F5.02
- ERO1-like protein 2
- Thioredoxin domain-containing protein C13F5.05
- Thioredoxin domain-containing protein C959.05c
- Protein disulfide-isomerase C17H9.14c
- ERO1-like protein 1
- Tryptophan synthase
- Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2
Sequence:
MRSNTFGSVMRISWVVAFITMVQTLVSGVPLTDNDLESEVSKGTWFIKYYLPSCGACKRLGPMWDNMVEKAKEQVEGSNFHFGEVDCSKELSSCANIRAVPTLYLYQNGEIVEEVPFGASTSEASLLDFVETHLNPDTDPDIPSDEDVLTDEDTEEVASIQPALSTSVSSLSLASTAMSKSASASEFSGSSVTKASKKLTSSPTSVASKKATLSSVSKVASTSSLPVTSVSASVDPKSAASKVQDAEFSIQTAPSFPKEKEEKENTEETEESKKSINPTGTSKALALDADIDAALTDKEGWFIQFYSSECDDCDDVSTAWYAMANRMRGKLNVAHINCAVSKRACKQYSIQYFPTFLFFKEEAFVEYVGLPNEGDLVSFAEEAANFEIREVELLDTVNAEKNGDVFFLYFYDDDSAEYLNIIRKTGIQLLGHANLYLTTSQQIAKKYRVVSFPKLIVVRDGIASYYPAKMAQDNKDYRRILGWMKNNWLPVLPELRTSNSKEIFNDESVVLFLLNPELDDFDETKRTAQKIATEFLDEEGRTYQSNWQKETDKKNSLVNEAEEKNDLEAIEAAKNFHVNGKPSPTRFAWVNGKFWAQWLRKFDIDIEATGPRVIVYNAAQDIYWDETAKGTPISIEKDTVFDIIKQVETDPDHLKFKILKKNLGVEYLESYGLNIRVLYMVLGIVTVGILVWYFSGRRARTLQRRRHSTPILPVSMRSTGNSGKFD
Protein: COP1-interacting protein-like protein (F4K5Y5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKSSTRLDSVAFQLTPTRTRCDLLVTANGKTEKIATGLLDPFLAHLKTAKDQLEKGGYSIILKPEASDNAAWFTKGTIERFVRFVSTPEVIERVYTLETEIIQIKEAIGIQNNSEMALTVVSILGLLNTFFVVWSEVLNGILYKQVKDDHRAKKADSAEGSRPLLQLNEEKAIVLYEPDSHPKQANRSTSSDENSKYTPLRELFFGFQCFSTKRVVKYLIGNMWNCIRAQVMKVLETRKIMLQKEQGMAFARAVAAGFEADDMIPLISFAKTFGASRLMDACVKFMDLWKKKHETGQWVEIEATEVMATQPNISTMNDSGIMFANAANMPGTPENSDAKSPTDNKRNGNQEYVQGQHRQPMYAPWPVHSPPGTFPVFQGYTMQGMPYYPGYPGASPYPSPYPSTDDSRRGSGQRKARKHHSSCSEDSESEDQERDNEKSSRRRKSGKVVIRNINYINSKKQDNSGTESDADDNHEEVARGECYNGKERATKGTEADTGDWQAFQTFLLQDADRDERSIDHMMEKEIRGKKRQGTGKYDPLAHGERESGKYQERDTADIRNGSVTRRIRGSSDSLMVHQRENGFENSSDPLNMNGFDTPRNGLDKRNMDDDSYIVTRVSSARDEAGRNKRNAIDIGSEISSCYQTDGNERKQVNYEPHDLSLIPERETEKLSAGYDPALEFGSKALKKNSQAAGGAKKLVKDPKSRLSKDAADKRKAPGPIRKGRPTKMSPLDEARARADKLRNFKADLQKMKKEKEEEDRKRIEALKIERQKRIASKSNSAVGQSQLPAQQTKKQILNKFSPGSRASKFSDSEPGSLSPLQRLPRRTTSLGSNDFQKFPKNGKLSTVSKSTGNMLTRSISPLPPAKRESIATGIRLTRSISPLPLSKRETRVSLDTQNKSVSQTRRLSEPKMGNTSAPSSSVRPRRTIASRKASDAPEIKKLSAIVNYDIAKIASLPELKIKPTKGPSNVMVKGVEKTKSSASGIEPSGNKNKSLCQNDIDETPVVEKTVVMVLPSSARSISRDQVKNEKSDVVSENSTIREGVDKEGIVETMQECGNDLVLVRLETLSDLVTETPKFLTSQSIVAKPYEAPYARVSSLEDPCTVYSDCSQAPPPSLYSNETEQETVKVLVPEKKISEASEKSQTKESASKGLRKLLKFGKKSQSSSVSEHHTESNNASFNSNEDHEPAVTAATTSEAFTLKNLISQDETPTAAAASQKSSRHFSLLSPFKNKKTVS
Protein: Speedy protein 1-A (Spy1-A) (Protein Ls26) (Rapid inducer of G2/M progression in oocytes A) (RINGO-A) (XSpy1-A) (p33 ringo-A) (xRINGO-A) (Q9PU13)
Organism: Xenopus laevis (African clawed frog)
Function: Stimulates oocyte maturation by promoting meiotic G2/M progression in resting oocytes, via activation of the MAPK cascade and cdc2-cyclin B. Also activates the kinase activity of cdk2; this activation does not appear necessary for oocyte maturation. Necessary for polyadenylation in oocytes.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q5MJ70}.
Interaction partners:
Sequence:
MRHMQSVTRATSICGSGVKQVIGKGHPHARVVGARKARIPEREELSVKPKMVRNTHLNLQPQERQAFYRLLENEQIQEFLSMDSCLRISDKYLIAMVLAYFKRAGLYTSEYTTMNFFVALYLANDMEEDEEDYKYEIFPWALGDSWRELFPQFLRLRDDFWAKMNYRAVVSRRCCDEVMSKDPTHWAWLRDRPIHHSGAMRGYLRNEDDFSPRGPGLTPASCTLCHKAGVCDSGGVSHNNSSSPEQEIFHYTNREWSQELLMLSPELLLDPECTHDLHILQEPLVGLEPDGTALEWHHL
Protein: Large ribosomal subunit protein uL24y (60S ribosomal protein L26-2) (Q9FJX2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein eL8z
- Large ribosomal subunit protein eL8y
- Large ribosomal subunit protein uL22y
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein uL4y
- Large ribosomal subunit protein eL32z
- Large ribosomal subunit protein uL6x
Sequence:
MKFNPRVSSSRRKNRKAHFTAPSSVRRVLMSSPLSKDLRNKHNVRSMPIRKDDEVQVVRGTFKGREGKVMQVYRRKWVIHIERITREKVNGSTVNVGVNASNVMITKLRLDKDRKSLLERKANGRAAADKEKGTKFSAEDVMENVD
Protein: Pathogenesis-related protein 1 (PR-1) (P33154)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Partially responsible for acquired pathogen resistance.
Subcellular location: Secreted, extracellular space, apoplast.
Interaction partners:
- Glucan endo-1,3-beta-glucosidase, acidic isoform
- Pathogenesis-related protein 5
- Hevein-like preproprotein
- Basic endochitinase B
- Regulatory protein NPR1
- Defensin-like protein 16
- Isochorismate synthase 1, chloroplastic
- Lipoxygenase 2, chloroplastic
- Lipase-like PAD4
- Lipoxygenase 3, chloroplastic
Sequence:
MNFTGYSRFLIVFVALVGALVLPSKAQDSPQDYLRVHNQARGAVGVGPMQWDERVAAYARSYAEQLRGNCRLIHSGGPYGENLAWGSGDLSGVSAVNMWVSEKANYNYAANTCNGVCGHYTQVVWRKSVRLGCAKVRCNNGGTIISCNYDPRGNYVNEKPY
Protein: Ammonia monooxygenase alpha subunit (AMO) (EC 1.14.99.39) (Acetylene-binding polypeptide) (Heterotrimeric Cu-heme enzyme) (Q04507)
Organism: Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Function: Part of the ammonia monooxygenase complex, which catalyzes the oxidation of ammonia to hydroxylamine, the first reaction in the process of ammonia oxidation to nitrite.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19453274}; Multi-pass membrane protein {ECO:0000305|PubMed:8468301}. Cytoplasm {ECO:0000269|PubMed:19453274}. Note=Ammonia monooxygenase is active and distributed approximately equally in both subcellular fractions. {ECO:0000269|PubMed:19453274}.
Interaction partners:
- Ammonia monooxygenase beta subunit
- Ammonia monooxygenase subunit C
- Ammonia monooxygenase subunit C2
- Hydroxylamine oxidoreductase
- Ammonia monooxygenase 3 subunit C
- Glutamine synthetase
- Glutamate dehydrogenase
- Possible
- LPXTG-motif cell wall anchor domain-containing protein
- Cytochrome c-554
Sequence:
MSIFRTEEILKAAKMPPEAVHMSRLIDAVYFPILIILLVGTYHMHFMLLAGDWDFWMDWKDRQWWPVVTPIVGITYCSAIMYYLWVNYRQPFGATLCVVCLLIGEWLTRYWGFYWWSHYPINFVTPGIMLPGALMLDFTLYLTRNWLVTALVGGGFFGLLFYPGNWPIFGPTHLPIVVEGTLLSMADYMGHLYVRTGTPEYVRHIEQGSLRTFGGHTTVIAAFFSAFVSMLMFTVWWYLGKVYCTAFFYVKGKRGRIVHRNDVTAFGEEGFPEGIK
Protein: Tudor domain-containing protein krimp (Protein krimper) (A1ZAC4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17428915, ECO:0000269|PubMed:22303351, ECO:0000269|PubMed:26295961}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:17428915, ECO:0000269|PubMed:22303351, ECO:0000269|PubMed:26295961}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000269|PubMed:17428915, ECO:0000269|PubMed:22303351, ECO:0000269|PubMed:26295961}. Note=Component of the perinuclear meiotic nuage (also known as germline granule or P granule), a germline-specific membraneless ribonucleoprotein biocondensate involved in post-transcriptional regulation of transposons and mRNAs (PubMed:17428915, PubMed:22303351, PubMed:26295961). Colocalizes with vas/vasa in the perinuclear nuage but not the pole plasm (PubMed:17428915). Localization to the nuage is dependent on spn-E, vas and aub but not mael or AGO3 (PubMed:17428915, PubMed:22303351). Localization to the nuage does not require tub in ovaries but does in testes; tub and aub are required for krimp protein stability in testes (PubMed:22303351). {ECO:0000269|PubMed:17428915, ECO:0000269|PubMed:22303351, ECO:0000269|PubMed:26295961}.
Interaction partners:
- Protein aubergine
- Protein argonaute-3
- Protein piwi
- Probable ATP-dependent RNA helicase spindle-E
- Mitochondrial cardiolipin hydrolase
- Qin
- Probable RNA helicase armi
- Protein vreteno
- Putative ATP-dependent RNA helicase SoYb
- FI02030p
Sequence:
MNLEDISMIMKLFDSNMHKLQGNLRSYQTEMHQIHKELTEKLSHADLLYRSLIPLHDHLVASLSEVNAHVMKLNVQLHINRQSVRLGDYEYYEKSIDNPYSSIRSGLQAIEKPGCAEAICQSSKPAFVECLPSSTSEEVPVVAVQEASSTNQLDAISVVNENLSEERDATPQPLAVSKNMEETMPSNPFHEQLEGSLEEIPVGSKIVVETEKANNPVRSEASAPATSDNQSLLAAKQGTQTIGTGICNKISKSTINMPNNWQLENPTEVTAASIEKVNKLPKSPRNRFLLPPKGGTETTRRDIYNQILKDMAAFPENTIVTAVLASVDVTDNCAYVAKWDESSDRIKKVLQRQLPLQELDQLPDYGDIFAVLDSINNIITRITINSSSAGGGYDAYLIDFGEHIHFDGNETIFKLPDDIKRLPAQAIRCDLINCDIANMHCFVNTYIKIRVHENNNSTLVAEPVIDRLSRPTKTNTTKYPAGITEDDMAMLNEIDESTSDPLKAVLGFRPKDEQRICRHYDPKLNGCFKGNNCRFAHEPFAPNGATKDVELARALPETIFDTTVHFEIGSIVGILITFINGPTEVYGQFLDGSPPLVWDKKDVPENKRTFKSKPRLLDIVLALYSDGCFYRAQIIDEFPSEYMIFYVDYGNTEFVPLSCLAPCENVDSFKPHRVFSFHIEGIVRSKNLTHQKTIECIEYLKSKLLNTEMNVHLVQRLPDGFLIRFLDDWKYIPEQLLQRNYAQVSQ