wanglab/gogpt-training-data huggingface dataset:
Protein: Estrogen-related receptor gamma b (Q5RJ38)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR002527}.
Interaction partners:
- G-protein coupled estrogen receptor 1
- Zinc finger protein ZFPM2 isoform X1
- Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
Sequence:
MDLVQFYHPESFSFPSEQNAFMDMMSFSGHCPPYIKTEPSSPSSLSDSLTQHSPGASSDAGSSYSSGPKGNLAGLDSPASYLRSAPCRLLEEAQAKGEYGLSSGPKRLCLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYSCSVSRDCEITKRRRKSCQACRFTKCLSVGMLREGVRLDRVRGGRQKYKRRIDSDSSVYLSVPLPHRKPVSCSAHAENKVVTLLLGAEPEKVCAMPDPALPDSDIKALTTLCDLADRELVLNISWAKHIPGFSSLSLSDQMSLLQSAWMEILVLRVAFRSLPCDDRLLFADDYIMDAEQAKCAGLLELHTAILQLVRRYRCMSLEREEFVTLKAIALANSDSMHIEDVEAVQGLQDALHEALLDYECVHHSEDPRRAGKLIMTLPLLRQTSAKAVRHFCSIKQDGRVPMHKLFLELLEANI
Protein: Large ribosomal subunit protein uL30C (60S ribosomal protein L7-C) (O60143)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P05737}. Nucleus {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- mRNA export factor elf1
- Elongation factor 3
- Large ribosomal subunit protein uL1B
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL6
- Ribonucleases P/MRP protein subunit pop3
- Large ribosomal subunit protein eL13
Sequence:
MAVASSTVPSKEQIFAPESLLKKKKTQEQSREQRVAAAAEKKAAQQKKRELIAKRAESYDAEYRKAEREQIELGRKARAEGNYYVPDETKLVFVIRIRGINNIPPKARKIMQLLRLIQINNGVFVKFNKATKEMLQVVEPYVTYGIPNLKTVRELLYKRGFGKVNKQRIALSDNAIIEAALGKYSILSIEDLIHEIYTVGPNFKQAANFIWPFQLSSPLGGWRDRKFKHFIEGGDAGKRDEHINSLVRKML
Protein: Gastric inhibitory polypeptide receptor (GIP-R) (Glucose-dependent insulinotropic polypeptide receptor) (P43219)
Organism: Rattus norvegicus (Rat)
Function: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Gastric inhibitory polypeptide
- Pro-glucagon
- Pituitary adenylate cyclase-activating polypeptide
- Pro-opiomelanocortin
- VIP peptides
- Natriuretic peptides A
- Neuroendocrine secretory protein 55
- Guanine nucleotide-binding protein G
- Dipeptidyl peptidase 4
Sequence:
MPLRLLLLLLWLWGLSLQRAETDSEGQTTGELYQRWERYGWECQNTLEATEPPSGLACNGSFDMYACWNYTAANTTARVSCPWYLPWYRQVAAGFVFRQCGSDGQWGSWRDHTQCENPEKNGAFQDQKLILERLQVVYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHMNLFTSFMLRAGAILTRDQLLPPLGPYTGNQTPTLWNQALAACRTAQILTQYCVGANYTWLLVEGVYLHHLLVVVRRSEKGHFRCYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILITILINFLIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLMPLLGVHEVVFAPVTEEQAEGSLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRRLRLSLQEQCPRPHLGQAPRAVPLSSAPQEAAIRNALPSGMLHVPGDEVLESYC
Protein: Dynein regulatory complex protein 8 (EF-hand calcium-binding domain-containing protein 2) (Q9CQ46)
Organism: Mus musculus (Mouse)
Function: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A8J3A0}.
Interaction partners:
- Gypsy retrotransposon integrase-like protein 1
Sequence:
MAEERDAEGTEALIAELHKKIKDAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDFIAEIEEEEPTGYIRFEKFIPVMTRALVERRYRPAAEDILLRAFEVLDPAKRGFLTKDELVKYMTEEGEPFSQEEMEEMLSAAIDPESNTINYRDYITMMVVDEN
Protein: Trace amine-associated receptor 13c-like (Trace amine-associated receptor 16f) (A0A0R4IIY1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MSNWGGTNTNNETIQYCFPNNNLSCTRNVKPGAEYIFVYIFISTVSVLTVFLNLLVIISIAHFHQLHTPTNVLIFSLAMSDLIVGLILMPVLGLKLIEPCWYFGEIFCSIFPFILYVVTTASLGNLIIISVDRYIAVNDPLRYTTRVDTNRAVYSIVVNWVFSSIYSLLIMYEAILYPEKNHTCIGECIFFIKLEYIITDALVCFVTPCCLIIYLYLKICFIAKHQAEHINALTDRKVKSEKKAAKSLGVVVMIYLLCWIPYYIAALTLGQDTNDSLVINIMYWILCMNSLMNPLIYAMYYKWFRISTKYILTLKILEPSSQYFNLFMEEK
Protein: von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein) (O00534)
Organism: Homo sapiens (Human)
Function: May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Interaction partners:
Sequence:
MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQGPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDYSLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVDPAIFAF
Protein: KxDL motif-containing protein LO9-177 (Q6ASS9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Contributes, together with ILI5/BUL1 and BC1, to the promotion of leaf inclination and grain size by modulating cell elongation.
Subcellular location: Nucleus {ECO:0000269|PubMed:27879391}. Cytoplasm {ECO:0000269|PubMed:27879391}.
Interaction partners:
- Os05g0290300 protein
- N-acetylglucosaminylphosphatidylinositol deacetylase
- Protein preY
- Os01g0166400 protein
- Os05g0165400 protein
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Os12g0638800 protein
- Os02g0622200 protein
- Os01g0224500 protein
Sequence:
MEKSPPETAAAAAEVAARFRSLVDTGDIGAIRQTQHLILGRLQDSNAVLTHFNEYSEQCFAEVSNDFASKTRLLKSMKDDLDHIFLKLRSMKSRLAATYPDAFPDGAMAKTMDQRPDLESPLD
Protein: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma) (EC 3.1.4.35) (P04972)
Organism: Bos taurus (Bovine)
Function: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
Interaction partners:
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanylate kinase
- Inosine triphosphate pyrophosphatase
- Adenine phosphoribosyltransferase
- GMP synthase
Sequence:
MNLEPPKAEIRSATRVMGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII
Protein: Cysteine protease (EC 3.4.22.-) (M9PBM3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU363115}.
Interaction partners:
Sequence:
MLVGLSDQLARIMESVFEAYLGPDSVLASAVGQAVGSGEPEDIPRRNTDVWVLGKKYNAIQELELIRRDIQSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTPDCRDATYLKIVNRFEDVRNSFYSIHQIAQMGESQNKAVGEWLGPNTVAQILKKLVRFDDWSSLAIHVAMDSTVVLDDVYASCREGGSWKPLLLIIPLRLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTAAAEQDYDETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLKEEVLSLCSPALFEISQTRAVDWDTTEDIDWPTMPDIDWPAGTSDSDSFAIVESGRDSDAGCSGAIGSGKKPSERAVI
Protein: Nucleolar protein 16 (Q9Y7Z1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the biogenesis of the 60S ribosomal subunit.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Ribosome biogenesis protein erb1
- Uncharacterized RNA-binding protein C1827.05c
- Ribosome biogenesis protein rlp24
- Probable rRNA-processing protein ebp2
- ATP-dependent RNA helicase has1
- AdoMet-dependent rRNA methyltransferase spb1
- Brix domain-containing protein C4F8.04
- Ribosome biogenesis protein nsa1
- Ribosome biogenesis protein brx1
- Ribosome biogenesis protein nsa2
Sequence:
MANPRQRNKQRSGKPRLTRRNANKKAKAKIYGNFVIQQNWDKHATLRQNYARLGLLATPNYVTGGVEKLYPDPKRENEDRELTSEELDELKKSLPPGQAIVRRDDDGNIIEIIHGEAKTLDDVLDKEISIAPAKTEVVRQLEEEAVKKAARQSNKMLPLSAFEHAYIQRLINKYGTEDFESMAKDVKLNSKLFNGSKLKNLYIRMKATK
Protein: Transcriptional regulator HrpG (Q3BW18)
Organism: Xanthomonas euvesicatoria pv. vesicatoria (strain 85-10) (Xanthomonas campestris pv. vesicatoria)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- histidine kinase
- histidine kinase
- Two-component system regulatory protein
- Two-component system response regulator KdpE
- histidine kinase
- histidine kinase
- HrpF protein
- ATP-dependent RNA helicase
- HrpE
- histidine kinase
Sequence:
MNDHSPSNAGSVFLLTQDARLTSQVNASLAPLARNVSTFSDELELLRSLRHSPCELLIFDASCVAADDSSLLAWQRCHSGQPTPLIVLGRFDCADNILAWYRAGAQEVLALPFNSHELHVRAALAISPVAHACPETQHLSVGPYKLIRDENTVYLEGKPIALTAREFSIAWLLFSSPGVCFRRCQLAKAVWGSHTEFTDRTMEQHIYKLRKKLQLSGDSSAVRIRTVYSHGYKLELALHDTEATTMSKAVSPSLGPAHHAAAC
Protein: Tektin-2 (Q2T9Q6)
Organism: Bos taurus (Bovine)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia (By similarity). Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37327785}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q922G7}. Note=Colocalized with CCDC172 at the perinuclear region. {ECO:0000250|UniProtKB:Q922G7}.
Interaction partners:
- EF-hand domain-containing family member C2
- RIB43A-like with coiled-coils protein 2
- EF-hand domain-containing protein 1
- Goosecoid homeobox.
- Cilia and flagella associated protein 45.
- Tektin-4
- Tektin-3
- Tektin-1
- Methyl-CpG-binding domain protein 1
- Parkin coregulated gene protein
Sequence:
MATLSVKPSPRFRLPDWQTNSYLLSTNAERQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLAERIDTVSRWKEMLDKCLTDLDAEIDALAQMKESAEQNLQAKNLPLDVAIECLTLRESRRDIDVVKDPVEEELHKEVEVIEATKKALQQKISQAFEKLFLLQEARQRLNSDHRGKMETLDIDRGCLSLNLTSPNISLKINPTRVPNGSTSLQQWDDLSRFNKDHGEAEMKKAIELREAIALTIAETNNELEAQRVATEFAFRKRLREMEKLYSELKWQEKNTLEEIAELHEDIRHLEEDLRRKLQNLKLCHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQDALDALYKHLARLQADIACKANSMLLDTKCMDTRRKLTVPAEKFVPEVDTFTRTTNRTLSPLKTCQLELA
Protein: RT1 class I, locus CE14 (A0A8J8XB15)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
LVPDLQSGAMVPPKLLPLLAAVLAPTQTQGGSHSLRYFKTAVSRPGLGEPRFMEVGYVDDTEFVRFDSDAENPRYEPRARWMEQQGPEYWERETQGAKEKEQTFRVNLRTLLGYYNQSEGDSHTLQLMFGCDVGSDGSLLRGYDQFAYDGRDYIALNEDLKTWAAADVVAQMTRNKWERARYAEKRRANLEGECVESLRRYLELGKETLLRSDPPKAHVTLHPRPEGDVTLRCWALGFYPAEITLTWQLNGEDLSQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCLVEHEGLPEPLTLRWGKEGVGADLGSGNAGAFCRPCRPWSGQRCGVMTPSFIS
Protein: Ribosomal lysine N-methyltransferase 4 (EC 2.1.1.-) (SET domain-containing protein 13) (Q9P6L2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42 (rpl42) at 'Lys-55'.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:20444689}.
Interaction partners:
- PWWP domain-containing protein 1
- Protein arginine N-methyltransferase 2
- Protein arginine N-methyltransferase 1
- Ribosomal protein arginine N-methyltransferase rmt3
- 20S-pre-rRNA D-site endonuclease nob1
Sequence:
MLKQAESMLKWAIEKDNYTTSEKIGLNDYRHVHESLGIGFIALEDIKEDEKLVSFKKDSVLCLTNSDLAQLPEVQSLPSWAALLLVMATENASPNSFWRPYLSIFPTKERITSPFYWDENKKDALLRGTVLESNEDCNEITQLWIDRIEPIIKLYPNRFSQVSYEDFLRMSAVMLAYSFDIEKTKSPISNENEKSAAETSIKEDKNGDAAKKNEGSANQDDEKLHSQSLVGNNCEVNSEDEFSDLESEVDPDELEKAMCPISDMFNGDDELCNIRLYDINGTLTMIATRDIKKGEQLWNTYGELDNSELFRKYGFTKKKGTPHDFVLIKKEHWLPEYIEKLGFEEVEARLELLCREELLYNLEGDFTFSKADLTFKEICLAFVLMEKEKELISVPSKSDIKPKHYRKLLKIIEKRINMYPKISDPKNFDEENAKTLIEGEIDILQNLSAKVKEALTKNRPKKKQKVDH
Protein: Photosystem I P700 chlorophyll a apoprotein A1 (EC 1.97.1.12) (PsaA) (P29254)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
Subcellular location: Cellular thylakoid membrane; Multi-pass membrane protein.
Interaction partners:
- Photosystem I reaction center subunit IX
- Photosystem I iron-sulfur center
- Photosystem I reaction center subunit XII
- Iron stress-induced chlorophyll-binding protein
- Photosystem I reaction center subunit XI
- Photosystem I reaction center subunit PsaK 1
- Photosystem I reaction center subunit PsaK 2
- Photosystem I reaction center subunit IV
- Photosystem I reaction center subunit VIII
- Photosystem I reaction center subunit III
Sequence:
MTISPPEREAKAKVSVDNNPVPTSFEKWGKPGHFDRTLARGPKTTTWIWNLHANAHDFDSQTSDLEDVSRKIFSAHFGHLAVVFVWLSGMYFHGAKFSNYEGWLADPTHIKPSAQVVWPIVGQGILNGDVGGGFHGIQITSGLFYLWRASGFTDSYQLYCTAIGGLVMAALMLFAGWFHYHVKAPKLEWFQNVESMMNHHLAGLLGLGSLGWAGHQIHVSMPINKLLDAGVAPKDIPLPHEFILEPSKMAELYPSFAQGLTPFFTLNWGVYSDFLTFKGGLNPVTGGLWLSDTAHHHLAIAVLFIIAGHMYRTNWGIGHSMKEILEAHKGPFTGEGHKGLYEILTTSWHAQLAINLALLGSLTIIVAQHMYAMPPYPYQAIDYATQLSLFTHHMWIGGFLIVGAGAHGAIFMVRDYDPAKNVNNLLDRMLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMRALGRPQDMFSDTAIQLQPIFAQWVQHLHTLAPGATAPNALATASYAFGGETIAVAGKVAMMPITLGTADFMVHHIHAFTIHVTALILLKGVLYARSSRLVPDKANLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSIVIFHFSWKMQSDVWGTVSPDGSVTHVTLGNFAQSAITINGWLRDFLWAQAANVINSYGSALSAYGIMFLAGHFVFAFSLMFLFSGRGYWQELIESIVWAHNKLNVAPAIQPRALSIIQGRAVGVAHYLLGGIVTTWAFFLARSLSIG
Protein: DNA adenine methyltransferase YhdJ (EC 2.1.1.72) (Type II methyltransferase M.EcoKII) (M.EcoKII) (P28638)
Organism: Escherichia coli (strain K12)
Function: A beta subtype methylase, recognizes the double-stranded sequence 5'-ATGCAT-3' and methylates A-5.
Interaction partners:
- Chromosomal replication initiator protein DnaA
- LexA repressor
- DNA adenine methylase
- Type I restriction enzyme EcoKI methylase subunit
- DNA-cytosine methyltransferase
- Cell division protein FtsZ
Sequence:
MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYNIGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLFTIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALIDYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIVLDPFAGSFTTGAVAIASGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTGNLSKRSRLSEVDPDLITK
Protein: Protein EI24 homolog (Q54PW9)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
METFKEYVTKRIDNTIPQVKEMFKLIWLGVADSMKLKGAIIRTIKSEVLRKNFIHCIFLNGIIFLGTYLIYLYWVSPMLNYLLNHFPTLSNMFTIIYFSLWVYPVYIFSIIANSKWYTEIAKESFVISGRTTFANSTNGILSSFVDEIYRNLLFGVILVMSAIIAFIPYTNFINFVIITWLYSFWCFDYKWILRGKWNLLQRIQYFETHWAYMFGYGLIFTTCSFFFPMLIGNAIFSILYPLFIILSISAKPTKMVNQDGILPKQIPIFYVPEIIVNVILKLYVKYKNTRGAAKSTTPSPSPTTKQN
Protein: Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1) (Q91W97)
Organism: Mus musculus (Mouse)
Function: Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases (By similarity). Has low glucose phosphorylating activity compared to other hexokinases (By similarity). Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q2TB90}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q2TB90}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q2TB90}. Photoreceptor inner segment {ECO:0000269|PubMed:30085091}. Note=The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrion. {ECO:0000250|UniProtKB:Q2TB90}.
Interaction partners:
- GDH/6PGL endoplasmic bifunctional protein
- Glucose-6-phosphate isomerase
- Glucose-6-phosphatase 3
- Glucose-6-phosphatase catalytic subunit 1
- Non-selective voltage-gated ion channel VDAC1
- Glucose-6-phosphatase 2
- Phosphoglucomutase-1
- Peptidyl-prolyl cis-trans isomerase F, mitochondrial
- ATP-dependent 6-phosphofructokinase, liver type
- ATP-dependent 6-phosphofructokinase, platelet type
Sequence:
MFAVHLVAFYFTKLKEDQIKKVDRFLYHMRLSDETLVDIMARFQAEMEKGLGKDTNPTASVKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSQEGQQNVQMESQFYPMPNEITRGNGTELFDYVADCLADFMKTKNLTHKKLPLGFTFSFPCRQNKLEEGVLLSWTKKFKARGVQDTDVVNRLATAMKKHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYMGELVRLILLKMAKVGLLFGGAKSSALHTKGKIETQHVAAMEMSKEGLANTREILVDLGLEPSESDCIAVQHVCTIVSFRSANLCAAALATILTRLRENKKLARLRTTVGMDGTLYKTHPQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLTREQLLGVRDKMRAELEYGLKKKTHSLATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRVLLVKIRRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFTFSFPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGTMMTCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDEGRMCVNTEWGGFGDNGCIDDIRTQYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQMCGAGMAAIVEKRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKELAPQCDVTFMLSEDGSGKGAALITAVAKRLQQPRKDI
Protein: L-Lys-D/L-Arg epimerase (EC 5.1.1.-) (Cationic dipeptide epimerase) (C0QM06)
Organism: Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2) (Desulfobacterium autotrophicum)
Function: Catalyzes the epimerization of L-Lys-L-Arg to L-Lys-D-Arg (in vitro). Catalyzes the epimerization of positively charged dipeptides, with a preference for substrates with a basic amino acid in the second position. Has epimerase activity with L-Lys-L-Lys, L-Arg-L-Arg, L-Val-L-Arg, L-Val-L-Lys and L-Ala-L-Arg (in vitro).
Interaction partners:
- DUF1611 domain-containing protein
- HTH-type transcriptional regulator
- DUF1611 domain-containing protein
Sequence:
MKIKEITIWKEDLALTRPYTIAYETISAVENVFVLLETDNGITGIGAGSPAEDVTGETITATETALSLKLAPILQGKDIRSCFSLLKELNTALADTPAALAAADIALHDLAAKTMGLPLVDLLGRVHDRLPTSITIGIMPVKETLAEAEEYLGRGFSILKIKTGLNVEEDIERIIRLNETFKSKICMRVDANQGYEVEELHHFFKKTVGLVEFIEQPLKAEHLEKMGQLPQAIRRVSAADETLLGPRDAAQMLHAPRPFGIFNIKLMKCGGIAPGLEIANMAGHADIDLMWGCMDESIVSIAGALHAAFSSRATRYLDLDGSLDLARDIVNGGFILENGWMRTTDQPGLGVKRI
Protein: Small nuclear RNA-activating complex, polypeptide 4 (snRNA-activating protein complex subunit 4 isoform X2) (F1QVS5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Small nuclear RNA-activating complex, polypeptide 3.
- Small nuclear RNA-activating complex, polypeptide 1a.
- Small nuclear RNA-activating complex, polypeptide 5
- Small nuclear RNA-activating complex, polypeptide 1b
- Small nuclear RNA-activating complex, polypeptide 2
- General transcription factor IIA, 1.
- Transcription initiation factor IIA subunit 2
- TATA-box-binding protein
- General transcription factor IIB.
- Von Willebrand factor A domain-containing 7.
Sequence:
MASDDLRAQRDKIQREILALESTLGADSSIADQLSSDNSSDYESDDSGPTVKRVERDDLETERLRIQREIEELENALGADAALENVLQDSDHDTDSSEDSADDLELPQNVETCLQMNLVYQEVLKEKLAELEQLLIENQQQQKEIEVQLSGPGNSIFSVPGVPPQKQFLGYFLKPYFKDKLTGLGPPANEETKERMKHGSIPVDNLKIKRWEGWQKTLLTNAVARDTMKRMLQPKLSKMEYLSNKLCRAEGEEKEQLKAQIELIEKQIAEIRTLKDDQLLGDLQDDHDWDKISNIDFEGLRQADDLKRFWQNFLHPSINKSVWKQDEIYKLQAVAEEFKMCHWDKIAEALGTNRTAFMCFQTYQRYISKTFRRTHWTEEEDDLLRELVEKMRIGNFIPYIQMSHFMVGRDGSQLAYRWTSVLDPSLKKGPWSKEEDQLLRNAVAKYGTREWGRIRTEVPGRTDSACRDRYLDCLRETVKKGTWSYAEMELLKEKVAKYGVGKWAKIASEIPNRVDAQCLHKWKLMTRSKKPLKRPLSSITTSYPRNKRQKLLKTVKEEMFFNSSSDDESQINYMNSDESDDLAEDENLEIPQKEYVQTEMKEWIPRNAMVWTITPGSFRTLWVRLPTNEEELRESTKESGLGSDSSENSACPNDEPIMERNTILDRFGDVERTYVGMNTVVLHRRTDDEKAMFKVCMSDVKQFIQMKATEFAVKKKKKIKNKKRTLRDVFSLNTDLQKAVIPWIGNVIISTPANEAIFCEGDIVGIKAASIRLQKTSVFTFFIKAFHVDVNGCRTVIEIHKKLDIKMPLAINGNPKPTPISTSPKTVAVLLQQSKAASEHKKPAEPSQQPSLPPSQKPSLPPAQQPTQPPSLPPSVPPSQQPTLPPPSQPSQPPPQPPSLPPSQPPAQQPPQQPSLPPPQPPSLPPPQPPSLPTSQQQSLPPSQQHSLPPFQNPSLPPSQQPSLPPSKQPPQPLPVRQITTPTLIYPNNLVITNPNMEGEVQHLVFKGLLLPQQPSKAVSHIPLPVMQPKTPAQPIVVSKSPSVQDSNSVKSSKRICKPTKKAQALMEQSKVKSRKKEPQKQNQGNKNVVFPTVTLQTSPVIKILSPARLVQVTGLSPNFSSNQTINMPDKSLTIKSPQPCSSGNLHQSAPVVVHSSTNPTFVHSSVSNVSRDNLNVSSTINISPRVSRDALNPTSFLNSTTFPLPQNLSVQQSVQIVPQIPINVVHKATCTKAAKTSSDSSSDESVVKQHQLSPSTGRSIPPAVFNIQPNPSTPPTLSSGPVIFNPNNKVVAPKLCGLNVSSSQLPTVSTQKTKYRPIRPLGPLPVVAPPSRKVTSMSRIRAQSEGEPLISLRDLPAAGVNFDSHLIFPEKSSEVDDWMDGKGGIPLPHLDTSLPYLPPSAATIKTMTDLLRAKQPLLLAAKKVLPAQYQDECNEEVEVEAIRKVVAERFASNPAYLLCKARFLSCFTLPALLATINPCEERQLLSEDDEEDDHLATINPSEEHQSSTEDDEEDLQTNERSQPPTARTELNMNENEASAKQFSGIGPKRQRNQRIKRLIK
Protein: LRRGT00098 (Q6TUE6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLNWLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLANSLLHSDHNRSRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDIILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDSSDNYAEPLDTIFKQKGYPDEIYVVPDDSQNRIIKIRNSFVNNTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFPTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQEVDDKKIKKKPHKVKEDKKGFVSKG
Protein: Mitochondrial carrier protein, putative (Q385N9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004225}.
Interaction partners:
Sequence:
MEVVVSFLSGWAGGISNLLVGHPFDTVKTLMQGNKGEYKNSLHCAKRIVMEGGPFALYKGVIAPMTGTGVVMALYFVAYDATETLIRKLKGVDSLTPLSMGEIMLCGGSTGVLGSLVLGPAELLKVRQQTALSSGARGSLRDVILNIYRKEGPLGFTRGIGATMLRDVPGSMAWFGAYEYTKLLLCKNPKDPSVGEALFAGGMGGIAVWSFSLPLDCIKTRVQASPVPLTPVVAFRAILSEHGIKGFYRGIGPALLRAFPANAACFAARDKTKSTLNNLCGM
Protein: Berberine bridge enzyme-like Cyn d 4 (60 kDa pollen antigen) (BG60) (Cyn d BG60) (FAD-linked oxidoreductase BG60) (EC 1.-.-.-) (Pollen isoallergen BG60) (allergen Cyn d 4) (Q5QJ60)
Organism: Cynodon dactylon (Bermuda grass) (Panicum dactylon)
Interaction partners:
Sequence:
MARSRAFAFALLICAVAASCHVALSAPPPYAKQVERDFLTCLTKDIPPRQLYAKSSPAYASVWSSTVRNIKFLSDKTVKPLYIITPTNASHIQAAVVCGRRHGMRIRVRSGGHDYEGLSYRSEKPEPFAVVDMNKMRAVSIDGKAATAWVDSGAQLGDLYYGIAKASPKLGFPAGVCTTIGVGGHFSGGGFGMLLRKYGTAADNVIDAKVVDAQGRLLDRKAMGEDHFWAIRGGGGESFGIVASWQVKLLPVPPKVTVFQVHKGIKEGAIDLVTKWQTVAPALPDDLMIRIMAMGQGAMFEALYLGTCKDLVLLMTARFPELGMNATHCKEMTWIESVPYIPMGPKGTVRDLLNRTSNIKAFGKYKSDYVLEPIPKSDWEKIFTWLVKPGAGVMIMDPYGGGIASVPESATPFPRRSGVLFNIQYVVYWFGEGAAALPTQWTRDIYDFMTPYVSKNPRQAYVNYRDLDLGVNQVVGNVSTYASGKVWGEKYFKGNFERLARTKGKIDPEDYFRNEQSIPPLL