wanglab/gogpt-training-data huggingface dataset:
Protein: Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1) (P35347)
Organism: Mus musculus (Mouse)
Function: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
Subcellular location: Cell membrane {ECO:0000269|PubMed:8243652}; Multi-pass membrane protein {ECO:0000269|PubMed:8243652}. Endosome {ECO:0000250}. Note=Agonist-binding promotes endocytosis. {ECO:0000250}.
Interaction partners:
- Urocortin
- Corticoliberin
- Urocortin-2
- Urocortin-3
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
Sequence:
MGQRPQLRLVKALLLLGLNPVSTSLQDQQCESLSLASNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHIAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
Protein: B1 bradykinin receptor (B1R) (BK-1 receptor) (Q61125)
Organism: Mus musculus (Mouse)
Function: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P46663}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Kininogen-1
- B2 bradykinin receptor
- Angiotensinogen
- Guanine nucleotide-binding protein G
- Endothelin-1
- Prothrombin
- HMW kininogen-II
- Guanine nucleotide-binding protein subunit alpha-11
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit gamma
Sequence:
MASQASLKLQPSNQSQQAPPNITSCEGAPEAWDLLCRVLPGFVITVCFFGLLGNLLVLSFFLLPWRRWWQQRRQRLTIAEIYLANLAASDLVFVLGLPFWAENVGNRFNWPFGSDLCRVVSGVIKANLFISIFLVVAISQDRYRLLVYPMTSWGNRRRRQAQVTCLLIWVAGGLLSTPTFLLRSVKVVPDLNISACILLFPHEAWHFVRMVELNVLGFLLPLAAILYFNFHILASLRGQKEASRTRCGGPKDSKTMGLILTLVASFLVCWAPYHFFAFLDFLVQVRVIQDCFWKELTDLGLQLANFFAFVNSCLNPLIYVFAGRLFKTRVLGTL
Protein: Protein translation factor SUI1 homolog 1 (P41568)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably involved in translation.
Interaction partners:
- Eukaryotic translation initiation factor 4C
- Eukaryotic translation initiation factor 4C
- Eukaryotic translation initiation factor 3 subunit A
- Eukaryotic translation initiation factor 3 subunit E
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 3 subunit I
Sequence:
MSELDSQVPTAFDPFADANAEDSGAGTKEYVHIRVQQRNGRKSLTTVQGLKKEYSYTKILKDLKKEFCCNGTVVQDSELGQVIQLQGDQRKNVSTFLVQAGLVKKDNIKIHGF
Protein: LOB domain-containing protein 42 (ASYMMETRIC LEAVES 2-like protein 36) (AS2-like protein 36) (Q9CA30)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- LOB domain-containing protein 9
- LOB domain-containing protein 27
- LOB domain-containing protein 26
- LOB domain-containing protein 36
- LOB domain-containing protein 22
Sequence:
MRISCNGCRVLRKGCNQDCTIRPCLQWIKSADSQANATLFLAKFYGRAGLLNLIESGPDHLRPAIFRSLLYEACGRIVNPVDGSVGLMWSGNWAQCQAAVDAVLNGLPITHTPLPSASASHQIIPPHRTYDIRHVAKDPTTGGDSSENLATRVNANKSKTQTGRFKRESVNQLGECSHDMWQLPSSSATHGYGHFTLENVESRREAPFNQSSPNLGFDDQVDINEVGLELRLG
Protein: Elongation factor 1 alpha-like protein (EC 3.6.5.-) (P32769)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in protein translation. Together with DOM34, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Protein DOM34
- Small ribosomal subunit protein uS12A
- Small ribosomal subunit protein uS3
- Exosome complex component RRP43
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS10
- Translation initiation factor RLI1
- Putative pelota-like protein YCL001W-B
- Small ribosomal subunit protein eS30A
- Small ribosomal subunit protein uS7
Sequence:
MAYSDYSDGADDMPDFHDEGEFDDYLNDDEYDLMNEVFPTLKAQLQDYQGWDNLSLKLALFDNNFDLESTLAELKKTLKKKKTPKKPIAAANGSANVTQKLANISISQQRPNDRLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKENEGINKDDPFLFSVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYPSEQSCIVDKIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDKGNTASKKKIRHLGSKQRAFVEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ
Protein: Conserved oligomeric Golgi complex subunit 2 (Component of oligomeric Golgi complex 2) (D3ZT01)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 7
- Conserved oligomeric Golgi complex subunit 8
- Small integral membrane protein 7
- Vacuolar protein sorting-associated protein 53 homolog
- TPX2, microtubule nucleation factor
Sequence:
MEKRRMNLPTGPDTLCFDKDEFMKEDFDVDHFVSDCRKRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDKALNQLSVPLGQLREEVLSLRSSVSEGILAVEERMSKQDDIRKKKMSVLRLIQVIRSVEKIEKILNSQSSKDASSQEASSPLLTGQVLERIATEFNQLQFHAVQSKGMPLLDKVRPRIAGITAMLQQSLEGLLLEGLQTSNVDIIRHCLRTYATIDKTRDAEALVGQVLVKPYVSEVIVERVVDSHPSGLQLMYNKLLEFVPHHCRLLREVTGGAVSSEKGTIVPGYDFLVNSVWPEIVGGLEEKLPSLFNPGDPDAFHQKYTVSMDFVRRFERQCGSQASVKRLRAHPAYHSFSNKWNLPVYFQIRFREVAGSLEASLTDGLEDAPAGSPYCLLASHRTWISLSKCWSDEMFLPLLAHRLWRLTLQILARFSVFVSELSVRPISNETAKETKKPLAGSKDPSDDHGSHPSEAGAVPISSTQLVYVVSDLGRLQEWLPDLLETVRLKLEMVGFKNFSSISAALEDSQSALSAHVPALSSRIVQDLSESCFGYLKSALEVPRLYRRTNKEVPSTASSYVDSALKPLYQLQSGHGDKVQPAVMQRWLQEALSDSTHKYFETVSDVLSSVRKMEESLKRLKQARRSPATNPVSSSGGMSDDDKIRLQLALDVEHLGEQIQKMGLQTSDIKSFPALTELVLAARDQAAAEQP
Protein: Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) (O08719)
Organism: Rattus norvegicus (Rat)
Function: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P70429}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:P70429}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P70429}. Note=Targeted to the leading edge of lamellipodia and the distal tip of stress fibers through interaction with a number of proteins. In activated T-cells, localizes to the F-actin collar and the distal tip of microspikes. {ECO:0000250|UniProtKB:P70429}.
Interaction partners:
- Protein enabled homolog
- Vasodilator-stimulated phosphoprotein
- Profilin-1
- Profilin-2
Sequence:
MFAFEEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSTQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATGPILPPGHPSSAASATFSCSGPPPPPPPPVPPPPTGSTPPPPPPLPAGGAQGTNHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT
Protein: At3g52530 (Protein kinase superfamily protein) (Q9SVD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKGFFKTESETRKHSDKNGSLLHEELIACSDGKYNPIRMFSSDQILKATNNFDADHIIAKDRFIWYKGTIEERRVLIKKWEGDYVLFSSPENVYRDIAVLSMMSSHKNVLKLLGCCVEFYKPVLVCELAEKGPLKLEDMDGTPLPWSARLKIGKDIANAVAYLHTAFPRVIINRDVRPQNIFLDEDGTAKLSSFCLRISIPEGESSVYDDKVVYGVSVDPEYNGTGLVSEKFDVYSFGVTMLFLLGGELGLTWLSAIIGEFGFPFPGCGEELADQFMYVIDSNIWNGESEASAVQVETFFGLALRCIRFWPGQDVLTMIDVAKELKGIEELFKASSSEQDKEQIDQVNYSV
Protein: Dephospho-CoA kinase (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (P0A6I9)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00376, ECO:0000305}.
Interaction partners:
- Phosphopantetheine adenylyltransferase
- Cell division protein ZapD
- Coenzyme A biosynthesis bifunctional protein CoaBC
- Formamidopyrimidine-DNA glycosylase
- Pantothenate kinase
- Holo-[acyl-carrier-protein] synthase
- Nucleoside triphosphate pyrophosphohydrolase
- 4'-phosphopantetheinyl transferase AcpT
- DNA gyrase inhibitor YacG
- Bifunctional riboflavin kinase/FMN adenylyltransferase
Sequence:
MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP
Protein: Alpha-glucosidase MAL12 (EC 3.2.1.20) (Maltase) (P53341)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Invertase 2
- Maltose permease MAL31
- Maltose fermentation regulatory protein MAL13
- General alpha-glucoside permease
- Glucoamylase, intracellular sporulation-specific
- Maltose fermentation regulatory protein MAL33
- Alpha-glucosidase MAL32
- 1,4-alpha-glucan-branching enzyme
- Hexokinase-1
- Glycogen phosphorylase
Sequence:
MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
Protein: Paired box gene 2b (Paired box protein Pax-2b) (Transcription factor) (O93370)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDIHCKADPFSAMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPSPDGTSLSTPGHTIIPSTASPPVSSSSNDPVGSYSINGILGIPRSNGEKRKRDADGSEGSAQSSDSQGSVESLRKHLRADAFTQQQLEALDRVFERPAFPDVFPTSEHIKPEQASEYSLPALNTGLDEVKPSLSSSAASDLGASVSQSYPVGRDMANTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPAILSSPYYYSASRGSAPPTAATAYDRH
Protein: DnaJ (DUF3353) (Q94C78)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein CURVATURE THYLAKOID 1A
- Thioredoxin family protein
Sequence:
MNASGLTVTPPRFHFRWRSDRFGTSQRSSQAFTVLSKLNNRNSAWPVLKSSRLALPTQRRNAMITRAMSASFGDMADDSAAIFPRINVKDPYKRLGISRMASEDEIQGARNFLIQQYAGHKPSVDAIESAHDKIIMQKFHERKNPKIDISKKVRQVRQSKVVNFVFERFQTPPNAVLVKTAVTFAVLGVLTVLFPTEEGPTLQVLLSLIATFYFIHQRLQKKLWTFLYGAGAFIFSWLVGTFLMVSVIPPFIKGPRGFEVMSSLLSYVLLWVASSYLR
Protein: Cathepsin L-like cysteine proteinase (Q8IU31)
Organism: Brugia malayi (Filarial nematode worm)
Interaction partners:
Sequence:
MKAFFILHLASFLLLTYANPLNELDNDDTPGKIHTLYQQHYSKYKTYLKKMGKKHDPSVPEPIRLLKFVQSLKMIDEHNQRYSKGLETYKVDLNKMSDWTEEEKERLRGYYPNLTEYAEGDLSRIIRGNITTTIPKSFDYRKKITVLPASDQGRCGVCFIFSALGALEMYVALRTKKRPVKLSVQDVMDCSGMEKCKGRGGNEPAVFRWVAEHGVKTDKSYPYKENDSVSCPRNTPQRRKYGLADAFYLPPSNEQILKKILALYGPVCVSLHSSLQSFVAYRSGIYNDPKCPTNAEKVNHAVIAVGYGVQNGMEYFIIKNSWGPTWGQKGYGRIRAGVFMCGIGRFSNVPIFK
Protein: Maleylacetate reductase (MA reductase) (EC 1.3.1.-) (Q5W9E3)
Organism: Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum)
Function: Catalyzes the NADH-dependent reduction of maleylacetate to beta-ketoadipate, a step in the degradation of gamma-hexachlorocyclohexane (gamma-HCH or lindane). Has an essential role in this assimilation pathway that allows S.japonicum UT26 to grow on gamma-HCH as the sole source of carbon and energy.
Interaction partners:
- Putative intradiol ring-cleavage dioxygenase
- Probable beta-ketoadipate enol-lactone hydrolase
- Dienelactone hydrolase
- Carboxymethylenebutenolidase
- Carboxymethylenebutenolidase
- alcohol dehydrogenase
- Chlorocatechol 1,2-dioxygenase
- 2,6-dichloro-p-hydroquinone 1,2-dioxygenase LinEb
- LysR-family transcriptional regulator
- Dichlorophenol hydroxylase
Sequence:
MQFVYDPLPYRVIFGAGSVRRVADELSHVGSRALVLSTPEQAGSAQELAATLGDKAVGLFSKAVMHVPVATVDAAAAVARELDADCTVAIGGGSTVGLAKALSLRLDLPSLVVPTTYAGSEVTPIWGLTEDGIKTTGRDKKVLPKVVVYDPDLTLSLPAEMSIASGLNAIAHAMEGLYAFDGNPIVSLMAEESIRALARSLPLIKADPTDAKARGDALYGCWLAGSVLGAASVALHHKLCHTLGGTFDMPHAQTHTAVLPHAIAYNAPSVPEAMERASRALGGGDPATKLYELAVGLGAEMSLAKLGMPKDGIAKAAALAVANPYPNPRPITEEGIVQLLSRAVEGLPPITA
Protein: Cardiotrophin-1 (CT-1) (Q63086)
Organism: Rattus norvegicus (Rat)
Function: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Leukemia inhibitory factor receptor
- Interleukin-6 receptor subunit beta
- Ciliary neurotrophic factor receptor subunit alpha
- Leukemia inhibitory factor
- Cardiotrophin-2
- Oncostatin-M-specific receptor subunit beta
- Oncostatin-M
- Interleukin-11 receptor subunit alpha
- Ciliary neurotrophic factor
- Interleukin-11
Sequence:
MSQREGSLEDHQTDSSFSFLPHLEAKIRQTHNLARLLTKYADQLLEEYVQQQGEPFGLPGFSPPRLPLAGLSGPAPSHAGLPVSERLRQDAAALSALPALLDAVRRRQAELNPRAPRLLRSLEDAARQVRALGAAVETVLAALGAAARGPVPEPVATSALFTSNSAAGVFSAKVLGLHVCGLYGEWVSRTEGDLGQLVPGGVA
Protein: Survival of motor neuron protein-interacting protein yip12 (SMN-interacting protein yip12) (Yab8-interacting protein 1-b) (P0CU09)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:10749973}.
Interaction partners:
- Small nuclear ribonucleoprotein Sm D1
- SMN complex subunit smn1
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein-associated protein B
- Small nuclear ribonucleoprotein E
- U2 small nuclear ribonucleoprotein A'
- Small nuclear ribonucleoprotein F
- Small nuclear ribonucleoprotein Sm D3
- Splicing factor saf5
Sequence:
MPSKRKRNPLQYQTSGSLDEETNQRSAFPQIDNNSASESLEYDIPLDGLDYLATVREEARKLVPFVAARREPETRETIPLRKLEIEAGKKSFDPFLRYLLNIIDKEGERLEQYMESSSLDASILPKNLQQWRVYIEHKAPCWAILAVVDLATVLEILESLSSWLEKDAIDLQSQWIFCFCYKLPELLNGEDISTLRSVLKSLRSTHTSFPALQMSASALQAVLVYRYGQKDLFQT
Protein: Ras-related protein Rab-26 (Q9VP48)
Organism: Drosophila melanogaster (Fruit fly)
Function: Participates in exocrine secretion.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P51156}; Lipid-anchor {ECO:0000250|UniProtKB:P51156}; Cytoplasmic side {ECO:0000250|UniProtKB:P51156}.
Interaction partners:
Sequence:
MASTAVGLGGGEGDPGAGGPPAGSAHPDDASSMSDDVFEDAETTQARIEELRRRPFGDGSYNPPAAPASVSASITTTTTQQQQQHHNPSHHHQSSHHQPSHHHHHHHHSQLSLTGSHHYHDDAIMAPVQRSATGYPGYRPSREAMQMYAYGTDDYDDDYNDGWRSYRYDEVDMHPAPSNAHQQPFDDTVNHKTILLGDSGVGKTSFLVKYNTGEFRLGSFSATVGIALTNKVVVVDGTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQEDVVIVLIGNKADCSGSERQVKREDGERLGREHNVPFMETSAKTGLNVELSFTAVARQLKSRGYEHGDDGKFNVHDFVRDNTKARSVCAQCRNM
Protein: Bromodomain-containing protein 2 (H0Y799)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XRPLGVQQPGARLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAIL
Protein: Lipase chaperone (Lipase foldase) (Lipase helper protein) (Lipase modulator) (Q01725)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: May be involved in the folding of the extracellular lipase during its passage through the periplasm.
Subcellular location: Cell inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Periplasmic side {ECO:0000250}.
Interaction partners:
- Triacylglycerol lipase
- Lipase LipC
- Transporter
- Aromatic hydrocarbon degradation protein
- Bacteriophage N4 adsorption protein B
- Probable hydrolase
Sequence:
MKKILLLIPLAFAASLAWFVWLEPSPAPETAPPASPQAGADRAPPAASAGEAVPAPQVMPAKVAPLPTSFRGTSVDGSFSVDASGNLLITRDIRNLFDYFLSAVGEEPLQQSLDRLRAYIAAELQEPARGQALALMQQYIDYKKELVLLERDLPRLADLDALRQREAAVKALRARIFSNEAHVAFFADEETYNQFTLERLAIRQDGKLSAEEKAAAIDRLRASLPEDQQESVLPQLQSELQQQTAALQAAGAGPEAIRQMRQQLVGAEATTRLEQLDRQRSAWKGRLDDYFAEKSRIEGNTGLSEADRRAAVERLAEERFSEQERLRLGALEQMRQAEQR
Protein: RNA helicase (EC 3.6.4.13) (Q6PBB2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSHVAVENVHGLDQQLAALDLSSADVQGVTGRRYIPPHLRNKEAAKNDAPGGWDNGRSNGFVNGYHDGRDNRMNGGSSFAGRGPIRSDRGGRGGFRGFGYDNKEAGGWNVPKDNAYNSFGGRSDRGKSSFFNDRGSSSRGRYERGGFGGGGNSRWVEECRDEDWSKPLPPNERLEHELFSGSNTGINFEKYDDIPVEATGHNGPQPIDRFHDLEMGEIIMGNINLSRYTRPTPVQKHAIPIIKSKRDLMACAQTGSGKTAAFLLPVLSQIYTDGPGEALQAAKNSAQENGKYGRRKQYPISLVLAPTRELALQIYDEARKFSYRSHVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLLDMMERGKIGLDYCNYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGLRQTMMFSATFPKEIQILARDFLEDYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNGNITKDLLDILVEAKQEVPSWLESLAYEHQHKSSSRGRSKRFSGGFGARDYRQNSSSGGGGFGGRGGRSTGGHGGNRGFGGGKGGFGNFYSSDGYGGNYSQVDWWGN
Protein: At1g06730/F4H5_22 (PfkB-like carbohydrate kinase family protein) (Q9ASV2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MYHHAFSLKFHSFSPHYALSLSNFSTQSPNPLLPPFARVPHVTSSVCLRCRSSAADVSPVIYADGSSSICSFGETGDVAVVEKPIDVSTLGNLCVDIVLSVHELPPPSRGERKALMDELSMSPPDKKYWEAGGNCNMAIAAARLGLHCVAIGHVGDEIYGEFLLDVLHEEGIGTVALNGGTNEKDTSSFCETLICWVLVDPLQRHGFCSRADFKEEPAFSWITDLSDEVKMAIRQSKVLFCNGYDFDDFSPSFIMSTIDYAAKVGTAIFFDPGPRGKSLSKGTPDERRALAHFLRMSDVLLLTSEEVEALTGIRNPVKAGQEILRNGKGTKWVIVKMGPKGSILVTKSSVSVAPAFKVEVVDTVGCGDSFVAAIALGYIRNMPLVNTLTIANAVGAATAMGCGAGRNVAKRHQVVDLMKASKLNDEEKFFEQLLAENSESSRINLLSKGMIKDGRSNKQLIETISMEKVVSELLAELELGRCCVKASS
Protein: Replication termination factor 2 (Q10154)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Replication termination factor which mediates replication termination at the site-specific replication barrier RTS1. Stabilizes the replication fork stalled at RTS1 until completion of DNA synthesis by a converging replication fork initiated at a flanking origin.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:19416828}.
Interaction partners:
- Protein saf4
Sequence:
MGNDGGSLPTRNELVKEPGKVPPLDIDFKRSVKSSQFSQCAITDEPLYPPIVSCGLGKLYNKASILQMLLDRSSVPKSPSHIKSLKDVVQLQVELDDSGKVLWLCPITRHVMSDTYQFAYIVPCGHVFEYSALKQFGEKMCFQCNQVYEEKDVIPINPNAEQLKTLSKRLLDLALSEKTHSLNKASKKSNKNGDKKRKHVSKSNSKHAKHELRTNRMLDGENVKSETSVTDMERVKRVKI
Protein: SED5-binding protein 3 (Lethal with SEC13 protein 1) (SEC24-related protein 3) (P38810)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Subcellular location: Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}.
Interaction partners:
- Protein transport protein SEC23
- Protein transport protein SEC13
- Protein transport protein SEC31
- GTPase-activating protein NEL1
- Protein transport protein SEC24
- COPII coat assembly protein SEC16
- SED5-binding protein 2
- Small COPII coat GTPase SAR1
- Integral membrane protein SED5
- ER-derived vesicles protein ERV14
Sequence:
MSQQNILAASVSALSLDESTVHTGGASSKKSRRPHRAYHNFSSGTVPTLGNSPYTTPQLNQQDGFQQPQAFTPKQFGGFNNGSGSVMSTPVMVSQERFGASEASSPYGQSMLDMTAPQPTSHIVPTQRFEDQAQYLQRSFETCRDSVPPLPTTQFYCVDQGSCDPHLMSLSMYNIPESEHLRAATKLPLGLTIQPFSTLTPNDAEVPTIPLPMDGTPLRCRRCRAYANPKFQFTYDSSVICNICRVKMQVPGEHFAPMGPNGQRSDLNEKSELLHGTVDFLVPSIYNAIQEKELLPLHYVFLIDVSLLANENGSSLAMVEGVRSCIEYISDFQPNCEVAIIVYDNKLRFFNLRPDLDNAQEYIVSELDDVFLPFYNGLFVKPGNSMKIINDTLIKISGYISTDKYSHVPQVCYGSALQAAKLALDTVTGGQGGKIICSLNSLPTIGNGNLSLKRDNAHIAHVKCDNGFYKKLASDFLKSYISLDLYVTNAGFIDMATVGHPVEMTSGILKYYPHFQQETDAFTLVNDMVTNVSNIVGYQALLKVRCSTGLSVEQYYCDSSDNTDHDPIIPVLTRDTTLDVLLKYDSKIKTGTDVHFQTALLYTDIDGVRKVRSINTSGAVSNNIREIFKFINQNPVMRIMIKDVIKTLGDCDFVKIRRLIDDKMVEILTQYRGLVSSNSSTQLILPDSIKTLPAYMLAFEKSELMKPNAQSTRGNERIYDLLKYDSLNSAQLCYKLYPQIVPFHVLLEETDLTFYDANDKLLQINSSSINNLSVRASHSNFINGGCYLIFQGDTIYLWFNENTNRMLLQDLLSVDESLPVSQISLFSGTLPETGTSINQKASNVIKNWQQVVNKSSLPLVLLRPNVDQYYSNVMSQLLCEDKTVNRIESYDNYLVIMHKKIQEKLQKDDFIKVSTAATHENIHQKFVQF
Protein: Hybrid signal transduction histidine kinase L (EC 2.7.13.3) (Q54RP6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
Interaction partners:
Sequence:
MEGSKRDIIENSNNGNNKGVVIEELGETYYTNSKPSTSADCKYFRDSFEFGSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEKSNNETEKTLESNGDTTTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNSSNDIYMNSPSSTLSSPGNAGNNLPIGCTKPNVPKSPYSPSPPHLYKSNSTSYLKSSFFSGNGSSSSSSSTTTTNINSNNSNTNTYSTSTNVKKNNSNTNSNTNNNTNGNTNTNSNSNKKNINSNSSDNIIINDTADIMNRRRDRFKSFSWTIGESNSNSKFSELSMISSKCKSIKSEFTPLFETLTVFDESDKIRHSLIQNHYKTLLIQNPASPNRTLLTNLLQRRGHNLTTCPIDINHVLQLLQKESFSLFIFDPNESIINNTSNSISSNEPISLSSSSSYYNNNNSNNNSVNNNNNNNSGNSTNNNSPSSHTPNSPMIFQPIVSNICSNSGGSGNNSPHHIDNNNNSNQQQQQQQQQQQQQQQHQHQQQQQQSSSTTATTNNSCTLNQQQQQQQQQQQQQQQQQQQQQQSQPTTPTQSTQSPTTSISFSKKKNLTINTSFKTSPMSSPKSFNKPSQSPQNIFNNFSNTYNPNNIEFCKILKSKLTEFETVIVLTESTDPSEFCQYIDAGATDYIPQPISPILLDLRLTTCQKLVNNNLHLKKAESLKDATRKMVTCIENSPDCVEIWDPSGHIQYLNLAFSEMTGFARWELLGKEFSNLIDNTEIIPNMWATLTDKKTWNGFIRTRHNNNTLIYFEASISPVLDQFQQILYYNCTKRDVTQKRIDEESKTLEQNKIIEKSRLRLSMMSHDIRTPMSNIIGMADLLLDTSLSQHQHHYLEIIKNSSNTLLTIINDILDISKIEAGKLDIDYESFDFNATVSQVVESMAQRVQSKGLELLSYVDPKIPNILIGPSSRLNQILTNLLGNSLKFTDKGEISICCLLNDETDSEYEIKVDVRDTGIGIKKEALPLLFKAFTQAEGTITRQYGGSGLGLAICKELVHLAFNGEISVESQYGHGSTFTCILKFKKFLPSDSQNLLPASSPLQQQQQQQQHQQQTQFHQHQQQTQFHQHQQQQLQHQQHQQHQQLQQQQQQQQQLQQQLQQHQQHQLQQRQHHQQQLQQQQHHHHQQVHLQQQQQHEHDAQHNQHIQQQQQQQQQQQQQQQQHEHNNNGHHNSHGHNHHGSHHNHNHQHNNNNNNITINKLQHQEKKQKSNEQQLESITENSFSPIVEPMVISDPDTPEALNISQSPSPQSIHNGTTINQQPTSPLNTLGSKFDFSGAKMLFIERNDTSRGNLFKQLLAWNIQLELVEDGESGFRKWKQSIESNSPYSIIIMDLNTPGVDGASLPMRIKKELELMQQHLQQQQEQEQQQQQEQQQSELQKQPDVENKNSSQNNDNNNNNNKSNSSGGNQCIYRSPIIMLMPIQFLNSQLEDNLKDAGVCAILSKPIRMSQLADVFMMYLGPNSEHNNNNNYNNNNGNGYLNGGGGGGGSVNGTGNGTLQVGMSNDGGNGCGVVSFWNKQRRASAEEQEQDPSKLLGKVLVVDDNHINIQILSKMLQTVGCEVDSVLSGADALAKINQSSGDSYDAIFLDIQMPDMDGFQVSRKIREREKKFSLPRVAIIATTANVFKEDQLKCFDAGMDDFISKPIKRAEIKEIIKKYGKNGNHQSGSAYSLYKLS