wanglab/gogpt-training-data huggingface dataset:
Protein: PR domain zinc finger protein 14 (Prmd14) (Q6XSK8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSVSLSSHPAVRDRSLAVYPSLPGAHYADVLKSAHSIFHPLKSLGRMVTDAQTIMPFNFSGATPFFSHNSAIFHEQILNVSNIPYFQHIQPSQSVYNARHEDQSTGSLSDFSSPSSVKSSSALSSPVKDNFSCPQAAHPTPEHVRTYSFTEEDLFTVLYGYSKKQGQNAGHAISGLSFPPSTGKLVNTSEIKTYDDNTLMWEIFENGRLSHFVDGRGAPGNWMSLVKCARFPEEQNLIAVQCDGQIYYEACKEIRAGQELLVWYGDCYVQFLGIPLTLKEFIDDSEALPAEDSGEGFKCDRCGKVFAYKYYRDKHLKYTRCVDQGDRKFPCHLCNRSFEKRDRLRIHILHVHEKHRPHKCSVCGKSFSQSSSLNKHMRVHSGERPYKCVYCNKAFTASSILRTHIRQHSGERPFKCKHCGKAFASHAAHDSHVRRTHAKDKQLSCDVCGATFQEAQELKYHMKAHKKRPLLESSVVPPADENALFSTKESLHAQTQLADTFSFPGMTSISSEYRPWN
Protein: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2) (P04844)
Organism: Homo sapiens (Human)
Function: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:F1PCT7}. Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258
- Protein transport protein Sec61 subunit gamma
Sequence:
MAPPGSSTVFLLALTIIASTWALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLSSLGAQVPDAKKACTYIRSNLDPSNVDSLFYAAQASQALSGCEISISNETKDLLLAAVSEDSSVTQIYHAVAALSGFGLPLASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASAAAVLSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVLQKTSFTPVGDVFELNFMNVKFSSGYYDFLVEVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAILGSVTFLAGNRMLAQQAVKRTAH
Protein: Transcription factor MEE8 (Basic helix-loop-helix protein 108) (AtbHLH108) (bHLH 108) (Protein MATERNAL EFFECT EMBRYO ARREST 8) (Transcription factor EN 132) (bHLH transcription factor bHLH108) (Q9FRI0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required during early embryo development, for the endosperm formation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Protein disulfide isomerase-like 1-4
- Protein disulfide isomerase-like 1-2
- Protein disulfide isomerase-like 1-6
- Protein disulfide isomerase-like 1-1
- Protein disulfide isomerase-like 1-5
- Agamous-like MADS-box protein AGL81
- Late embryogenesis abundant
- Late embryogenesis abundant
- Late embryogenesis abundant
- Late embryogenesis abundant protein-related / LEA protein-like protein
Sequence:
MNKDEVFLRQWFEILYSLTNPEANSDLRRINNEKGVEKVGQKRSAESRREGKKKRVKTQCVIKSSDKSDHDTLLKKKRRERIRRQLETLKEITPNCPQSDINAILDCVIEYTNNLRLAHYKGSQGICDDWRLFTEAGAVLYYIDT
Protein: Paraflagellar rod component (Q384H8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSQLPLIHTQQKSTTRYCPSGDENSVAVFRPKLPFLSEVNSCALVVASSRSQGRSVSRSTSEGGQLTSASRLSWLLERRATARPATGRSLQWVELMERQGRQLIKAIAYSTSPVRCYFMAGDDEGCFLPSLCEPWPPTLTTEDELNQMIKRASVKAKEHIFADRWFGEGKQCAKEPLANTDAFKSVEESQMDIMREFVDLRSSVCSEFLKQVEIRRSLIDLVKKEKEARVAMLGEFISCCPPHPCRCLLLDMEVLEESAIPLEPAVGITCLYTSIVIGGHETLEETLLQQREVELQVLYDQHRFFIDAQKVLTDVRNREHERFESMMAYFAFALRLLREREALSVETTTPPGCDEGPRETKTRGKRFHMNYYKYLHVLGTIEVEEGARGRICAGEFTEIRHILYHFERKCRSSIVSTEELERQRLLLNTEMQQRLSIQNAEELALNETVCPRSFQELIETLMKKEREEWQRALEEARITRSIELVCEYEVYRRREIGLFEQQLRACARFLFLNTTDGAGRITVERWMREHEVLVVQREEAALRKRIVESEDQALTTWITAHRWMVDHDRHLQSIAKEKEDRRAVDRVIAEECAARGVVESLWAGEHYVLFGEVIRVPEGIYKFPEGRQSGEGRESSCGDGESTSRGLDIRQVVIANLGEFFNDRALLGFFDRRPVSPI
Protein: Small ribosomal subunit protein uS5 (C3SR27)
Organism: Escherichia coli
Interaction partners:
Sequence:
MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKSVEEILGK
Protein: UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase) (Q564Q1)
Organism: Caenorhabditis elegans
Function: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important for the synthesis of glycoproteins and glycolipids.
Interaction partners:
- Probable galactose-1-phosphate uridylyltransferase
- Galactokinase
- UDP-glucose 6-dehydrogenase
- UTP--glucose-1-phosphate uridylyltransferase
- dTDP-D-glucose 4,6-dehydratase
- Probable UDP-N-acetylglucosamine pyrophosphorylase
- dTDP-4-dehydrorhamnose 3,5-epimerase
- GDP-L-fucose synthase
- UTP--glucose-1-phosphate uridylyltransferase
- Probable delta-1-pyrroline-5-carboxylate synthase
Sequence:
MHILVTGAAGFIGSHTVLELLNSGYTVLCIDNFANAISVTDEHGNAISLKRVAQLTGKDVPFQNVDVCDEAALEKVFSENKFDGIIHLAALKAVGESVAKPLQYYSNNLVASLNLIQMCLKYNVKNFVFSSSATVYGPPSELPITEKSQTGQGITNPYGQTKYMMEQILIDVGKANPEWNVVLLRYFNPVGAHKSGLIGEDPKGVPNNLMPYVSQVAIGKLPVLTIYGDQFDTVDGTGVRDYIHVVDLAKGHVKAFDRIKTVGNIGTEIYNLGTGVGYSVRQMVDALKKVSGRDIPVKIGVPRPGDVASVYCDPSLAQEKLGWRAETGLEEMCADLWNWQTKNPQGFSA
Protein: Myoregulin (Q9CV60)
Organism: Mus musculus (Mouse)
Function: Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle.
Subcellular location: Sarcoplasmic reticulum membrane {ECO:0000269|PubMed:25640239, ECO:0000305|PubMed:27923914}; Single-pass membrane protein {ECO:0000305|PubMed:25640239}.
Interaction partners:
- Myoblast determination protein 1
- Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF
- Endoregulin
- Sarcolipin
- Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN
Sequence:
MSGKSWVLISTTSPQSLEDEILGRLLKILFVLFVDLMSIMYVVITS
Protein: Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274) (Q9EP73)
Organism: Mus musculus (Mouse)
Function: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9NZQ7}; Single-pass type I membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000250|UniProtKB:Q9NZQ7}; Single-pass type I membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000250|UniProtKB:Q9NZQ7}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Programmed cell death protein 1
- Cytotoxic T-lymphocyte protein 4
- T-lymphocyte activation antigen CD80
- Hepatitis A virus cellular receptor 2 homolog
- Inducible T-cell costimulator
- Programmed cell death 1 ligand 2
- T-lymphocyte activation antigen CD86
- Signal transducer and activator of transcription 3
- Lymphocyte activation gene 3 protein
- T-cell immunoreceptor with Ig and ITIM domains
Sequence:
MRIFAGIIFTACCHLLRAFTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQITDVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYPEAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQNHTAELIIPELPATHPPQNRTHWVLLGSILLFLIVVSTVLLFLRKQVRMLDVEKCGVEDTSSKNRNDTQFEET
Protein: Vacuolar protein sorting-associated protein 54, chloroplastic (AtVPS54) (F4JT76)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (By similarity). Probably involved in pollen tube elongation and other polar growth.
Subcellular location: Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Plastid, chloroplast. Note=Localized in the GARP complex in the Golgi and post-Golgi compartments.
Interaction partners:
- Vacuolar protein sorting-associated protein 52 A
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar protein sorting-associated protein 53 A
- Vacuolar protein sorting-associated protein 52 B
- Vacuolar protein sorting-associated protein 53 B
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 7
Sequence:
MDSHPSLMGRSITNSNRSSLDLGRPSSSSSSSPSPLTKSISDASSQSLSSILNNPHGGKSGVYGSDASWVGWWSSSTFVAPAEFAPVASTKLPGSELTRSDFHGYVSSISESHGRFEDIRKHTREESCGFDQESHVSGLAACLREVPSLYFKEDFALEDGATFRSACPFSSLNENLALQEKLSQYLDVVELHLVKEISVRSDSFFEAQGQLQDLNVKIVEGCSRIRELKETIRLLDRNLVDSARQIQELSSTRINMLELQRKLRLILYVNQALSALKLLVASADCAGALDITDDLQNLLAGDELTGLYCFRHLRDHVTSSIDSINSILTSEFMRISIHDTGEIDVLILSAANIRGSISSNGNTGEEVKLEEEDTSTLCDRLLPLVIGLLRTAKFPSILRMYRDTLTSEMKNAIKKAVADLLPILVARSLESDFSHGERSVDDGGGLSLASKLRTLSSEAFVNLLTAIFKIVQAHLVRASEVKKAIEWILCNIDGHYAADSVAAAIAVGAVAAETAQEIGFQGGSLVSSPLGKATSKAPPLQGKSSDASSLMNMSRNFRADVLRENTEAVFAACEVTHGRWAKLLGVRALLHPKLKLQEFMSIYDLTQEFITSTEKIGGRLGSSIRGTLQSQAKAFVDSQHESRMTKLKAVLDQETWDEIDVPEEFQSIISSLFASQRLISGKVDDADLNSYHSNRLPLNGSLTSGSGDQNSELRNEKSESSEGSVVSDAQVKPTVSPESLERSKAGVSSATNNQSNQKAHGKSNLFYQGVGYHMVNCGLILLKMLSEYIDMNNSLPALSSEIVLRVVEVLRFFNTRTCQLVLGAGAMQVSGLKSIKAKHLALASQVIDFTYTIIPETRRILFSKVPETRKPLLSVEIDKVAQDFRIHRDEIYTKLVQIMRERLLAHLHGLPKVVEGWNRPPDTNKQTKEFAWPLTREVGYLHRVLSETLHEADVQAIFRQVISIIHTQTSQTLTNLEISSTEAKKRLKLHVELILKCIRSLPSDNANQSDIPNWGQLDEFFAEHFREEEAGEAE
Protein: Heterogeneous nuclear ribonucleoprotein A/B (D6RBZ0)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY
Protein: Uptake hydrogenase large subunit (EC 1.12.99.6) (Hydrogenlyase) (Membrane-bound hydrogenase large subunit) (P31891)
Organism: Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha)
Function: This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions.
Subcellular location: Cell membrane; Peripheral membrane protein.
Interaction partners:
Sequence:
MSAYATQGFNLDDRGRRIVVDPVTRIEGHMRCEVNVDANNVIRNAVSTGTMWRGLEVILKGRDPRDAWAFVERICGVCTGCHALASVRAVENALDIRIPKNAHLIREIMAKTLQVHDHAVHFYHLHALDWVDVMSALKADPKRTSELQQLVSPAHPLSSAGYFRDIQNRLKRFVESGQLGPFMNGYWGSKAYVLPPEANLMAVTHYLEALDLQKEWVKIHTIFGGKNPHPNYLVGGVPCAINLDGIGAASAPVNMERLSFVKARIDEIIEFNKNVYVPDVLAIGTLYKQAGWLYGGGLAATNVLDYGEYPNVAYNKSTDQLPGGAILNGNWDEVFPVDPRDSQQVQEFVSHSWYKYADESVGLHPWDGVTEPNYVLGANTKGTRTRIEQIDESAKYSWIKSPRWRGHAMEVGPLSRYILAYAHARSGNKYAERPKEQLEYSAQMINSAIPKALGLPETQYTLKQLLPSTIGRTLARALESQYCGEMMHSDWHDLVANIRAGDTATANVDKWDPATWPLQAKGVGTVAAPRGALGHWIRIKDGRIENYQCVVPTTWNGSPRDYKGQIGAFEASLMNTPMVNPEQPVEILRTLHSFDPCLACSTHVMSAEGQELTTVKVR
Protein: DNA 3'-5' helicase (EC 5.6.2.4) (DNA 3'-5' helicase BLM) (H0YNU5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVLRNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVCTTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRVSTAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSDASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFSATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASINDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
Protein: Cytochrome b6-f complex subunit 5 (Cytochrome b6-f complex subunit PetG) (Cytochrome b6-f complex subunit V) (P0C392)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00432}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00432}.
Interaction partners:
- Cytochrome b6-f complex subunit 4
- Cytochrome f
- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic
- Cytochrome b6
- Cytochrome b
- Cytochrome b
- Photosystem II CP47 reaction center protein
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Os03g0178950 protein
Sequence:
MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
Protein: 43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein) (RING finger protein 205) (Q13702)
Organism: Homo sapiens (Human)
Function: Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of postsynaptic membranes.
Interaction partners:
- Muscle, skeletal receptor tyrosine-protein kinase
- Agrin
- Protein Dok-7
- Acetylcholine receptor subunit delta
- Acetylcholine receptor subunit beta
- Acetylcholine receptor subunit epsilon
- Dystroglycan 1
- Acetylcholine receptor subunit gamma
- Utrophin
- Acetylcholine receptor subunit alpha
Sequence:
MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
Protein: Transcription factor bHLH34 (Basic helix-loop-helix protein 34) (AtbHLH34) (bHLH 34) (Transcription factor EN 135) (bHLH transcription factor bHLH034) (Q9LTC7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor ORG2
- Transcription factor bHLH101
- Transcription factor bHLH100
- Transcription factor ORG3
- Probable nicotianamine synthase 4
- Ferric reduction oxidase 2
- Fe
- Transcription factor bHLH18
- Ferric reduction oxidase 3, mitochondrial
- Transcription factor NAI1
Sequence:
MYPSIEDDDDLLAALCFDQSNGVEDPYGYMQTNEDNIFQDFGSCGVNLMQPQQEQFDSFNGNLEQVCSSFRGGNNGVVYSSSIGSAQLDLAASFSGVLQQETHQVCGFRGQNDDSAVPHLQQQQGQVFSGVVEINSSSSVGAVKEEFEEECSGKRRRTGSCSKPGTKACREKLRREKLNDKFMDLSSVLEPGRTPKTDKSAILDDAIRVVNQLRGEAHELQETNQKLLEEIKSLKADKNELREEKLVLKAEKEKMEQQLKSMVVPSPGFMPSQHPAAFHSHKMAVAYPYGYYPPNMPMWSPLPPADRDTSRDLKNLPPVA
Protein: Zcf13p (A0A1D8PNM8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Zcf18p
Sequence:
MDKTNSPGKKDNRSSASPQIPKKRSRVRQPLSCSVCRKRKSKCDRARPCGTCIKKSIVHLCHYEDDNRPPINHFLPPEQQLHPTHIDNNGYIITDQPPPIHYQDPYNNHNHNHHFQQQQQQHHHNTNNDSNFDPSLSHIQANGHNQFQHQPLSSHSPQGNHQYLPIPPPPPPPPQSQQSQHPPSISPAGYNSSIKMSQAQISIPTPPPATKSSTSTSNHSSPNRPPTSSGQSSYHTTTTNNYSNFNPSTVSNINSKPKLNSISLPLPPPPPPPSVTTPSLPMPSTTKSSISGMSLHHDNTFGQVSIPSPIPPINELSPSLSRLKSLGSNSDGVLSPTTIGVNDLLNPSRSNGGYNQSDNTIPPPTHENSNPTAQSVLSDQTAPSSKSISSPQESESFSSNSLVSIPLGANSSLQINASDTMDVFTNAVFSLHSTGNEWQQSGTLSYLGLTKSDPFITILRNFTVHLFRSDEFLNVIRNDATRKRRNSNGSLISIRSSRTGDENLSPVATKRPKLDNNGNGNANGNGNGNSSASLNTVSMPMNRSNSNDSNYLSNNANFTDAFDMISENDKPSNNTPLETFSPSVQQQYESPKKTPGDMAFMQSFYNGGQKRQEYYRFVEDEVSKILPDKTNSFQLFCRYFRFVNPFIQIVDEHALLFDINPILPKFLKFNHEKFTEVKIKSENDLRTLGIFLLVLKLGYQTMIHNDNEHNNYNEQELSIIDSMQQLDNPTFNRIINLCIADGLITARSSFKLVQLLALLYHYKGMSPDDSHGLSSADSQILLGTIIRHAFSIGLNRDPTRYTTFDNLAKNQVLIKTWRHLWWFLVATDAMSALNTGCNLNVSSLDGCDVEYPHVSEDPTGEMNKIYEVLAKICEHYRNIVNKINNLRQKPKVVEILKETNQMERIFFDFFGKDFFKDVVCKPAKEPTNGNGFEEASKEHMEKVVKVFKYCLFIQLRTNLSGMYYKIAIHYENEYDKSKTPSMKAGIELFKIYIKSVVQLVYIMSYVLDNSVYLFGKNFDYMLTASNERYMIKTHSFLTSFFVRLLHQKKELSFKVFKEISYMSRLECINNLFDIVLEDVELFVGDFRRLSKTYINSYRLYIITFIVLRQSIDNSDAFFEKAASDQSFFHQGTNMIEFFSQQELNHLCRLCRDWRNIKEAQKKYKDAKKNAINTKDTDDNDNEEVGFDPLKELESKLFGSSFFDDDNIFSNLNNLSDEILDPVACKEDLIRLFNIYGDFNDLL
Protein: Dro3 protein (Q2UYM9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MVQMIFLFAILALMTIVLMEANTVSARDCLSGTFGGPCWAWSGEKCRRLCIEEGHVSGHCSGGMKCWCEGC
Protein: Rho GTPase-activating protein 33 (Rho-type GTPase-activating protein 33) (Sorting nexin-26) (Tc10/CDC42 GTPase-activating protein) (Q80YF9)
Organism: Mus musculus (Mouse)
Function: May be involved in several stages of intracellular trafficking (By similarity). Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12773384}. Note=Translocates to the plasma membrane in response to insulin in adipocytes.
Interaction partners:
- Cell division control protein 42 homolog
Sequence:
MLQAQKQSDPILPWGASWAGRGQTLRARSTDSLDGPGEGSVQPVPTTGGPGTKGKPGKRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPEREGPSLSGENELVFGVQVTCQGRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGTRAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSEEASLNIPAVAAAHVVKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRGFQVGFFPSECVELFTERPGPGLKADADSPLCGIPAPQGISSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGLGGAAAFREVRVQSVVVEFLLTHVEVLFSDTFTSAGLDPAGRCLLPRPKSLAGSSPSTRLLTLEEAQARTQGRLGTPTEPTTPKTPASPVERRKRERAEKQRKPGGSSWKTFFALGRGPSIPRKKPLPWLGGSRAPPQPSGSRPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGPAPAGSCESLSSSSSSSSSSSSSSSSESSAGGLGPLSGSPSHRTSAWLDDGDDLDFSPPRCLEGLRGLDFDPLTFRCSSPTPGDPAPPASPAPPASASAFPPRATPQALSPHGPTKPASPTALDISEPLAVSVPPAVLELLGAGGTPASATPTPALSPHLIPLLLRGAEAQLSDTCQQEISSKLAPTRGAPGQQSPGGMDSPLLPPPLPLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQEQGGTPPAPHSPFRRSLSLEVGGEPVGTSGSGIHPPSLAHPGAWAPGPPPYLPRQQSDGSLVRSQRPLGTSRRSPRGPSQVSAHLRASGAYRDAPEMAAQSPCSVPSQGSNPSFFSTPRECLPPFLGVPKQGLYSLGPPSFPPSSPAPVWRNSLGAPSALDRGENLYYEIGVGEGTSYSGPSRSWSPFRSMPPDRHNASYGMLGQSPPLHRSPDFLLSYPPPPSCFPPEHLTHSVSQRLARRPTRPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPVPRLPQKQRAPWGPHTPHRVPGPWGSPEPFLLYRPAPPSYGRGGEVRGSLYRNGGHRGEGAGPPPPYPTPSWSLHSEGQTRSYC
Protein: Natriuretic peptide Coa_NP1 (B3EWY3)
Organism: Crotalus lutosus abyssus (Grand Canyon rattlesnake) (Crotalus oreganus abyssus)
Function: Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity in rats.
Subcellular location: Secreted {ECO:0000269|Ref.1}.
Interaction partners:
Sequence:
SKRLSNGCFGLKLDRIGAMSGLGCWRLINESK
Protein: 4-oxalmesaconate hydratase (OMA hydratase) (EC 4.2.1.83) (Gallate degradation protein B) (Q88JX8)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Function: Catalyzes the conversion of oxalomesaconic acid enol (OMAenol) to 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA). Mediates the third step of gallate degradation pathway.
Interaction partners:
- 4-oxalomesaconate tautomerase
- 4-carboxy-4-hydroxy-2-oxoadipic acid aldolase
- HTH-type transcriptional regulator GalR
- 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase
- Isomerase
- Gallate dioxygenase
- Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Sequence:
MTSCAHPHCRSQRNMNTPQKSALVVSAHSADFVWRAGGAIALHAEQGYAMHVVCLSFGERGESAKLWRKGEMTEAKVKDARREEAMAAAEILGASVEFFDIGDYPMRADKDTLFRLADVYRRVQPEFVLSHSLKDPYNYDHPLAMHLAQEARIIAQAEGYKPGEKIVGAPPVYAFEPHQPEQCEWRPDTFLDITSVWDKKYAAIQCMAGQEHLWEYYTRVALQRGVQAKRNVGITSARNIVYAEGLQSVFPRVTENLA
Protein: Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Q8R4L0)
Organism: Mus musculus (Mouse)
Function: Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Subcellular location: Cytoplasm. Cell membrane. Cytoplasmic vesicle. Late endosome. Note=Localized to the plasma membrane and intracellular vesicles, including late endosomal vesicles.
Interaction partners:
- E3 ubiquitin-protein ligase CBL
- Huntingtin-interacting protein 1-related protein
Sequence:
MGSLSSRGKTSSPSPSSSGPDQEPVSMQPERHKVTAVALGSFPAGEQARLSLRLGEPLTIISEDGDWWTVQSEVSGREYHMPSVYVAKVAHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGCYSLSVRLSRPASWDRIRHYRIQRLDNGWLYISPRLTFPSLHALVEHYSELADGICCPLREPCVLQKLGPLPGKDTPPPVTVPTSSLNWKKLDRSLLFLEAPASGEASLLSEGLRESLSSYISLAEDPLDDA