wanglab/gogpt-training-data huggingface dataset:
Protein: WUSCHEL-related homeobox 9 (Protein STIMPY) (Q6X7J4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Homeodomain transcription factor required for meristem growth and early development. Promotes cell proliferation and prevents premature differentiation in meristematic tissues during postembryonic development. Essential for maintaining tissue growth during embryogenesis. May act by repressing TSS to promote meristematic proliferation. Involved in the transcriptional activation of a subset of cytokinin response factors. May act as a negative regulator of cytokinin signaling in the dark.
Subcellular location: Nucleus {ECO:0000269|PubMed:17706632}. Cytoplasm {ECO:0000269|PubMed:17706632}.
Interaction partners:
- Kinesin-like protein KIN-14E
- Probable WRKY transcription factor 2
- Mitogen-activated protein kinase kinase kinase YODA
- Protein CLAVATA 3
- Protein RKD4
Sequence:
MASSNRHWPSMFKSKPHPHQWQHDINSPLLPSASHRSSPFSSGCEVERSPEPKPRWNPKPEQIRILEAIFNSGMVNPPREEIRRIRAQLQEYGQVGDANVFYWFQNRKSRSKHKLRLLHNHSKHSLPQTQPQPQPQPSASSSSSSSSSSSKSTKPRKSKNKNNTNLSLGGSQMMGMFPPEPAFLFPVSTVGGFEGITVSSQLGFLSGDMIEQQKPAPTCTGLLLSEIMNGSVSYGTHHQQHLSEKEVEEMRMKMLQQPQTQICYATTNHQIASYNNNNNNNNIMLHIPPTTSTATTITTSHSLATVPSTSDQLQVQADARIRVFINEMELEVSSGPFNVRDAFGEEVVLINSAGQPIVTDEYGVALHPLQHGASYYLI
Protein: Mersacidin decarboxylase (EC 4.1.1.-) (Mersacidin-modifying enzyme MrsD) (Q9RC23)
Organism: Bacillus sp. (strain HIL-Y85/54728)
Function: Catalyzes the oxidative decarboxylation of the C-terminal cysteine residue of mersacidin to an aminoenethiol residue.
Interaction partners:
Sequence:
MSISILKDKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKTAEDLIPAHTVSYFCDHVYSEHGENGKRHSHVEIGRWADIYCIIPATANILGQTANGVAMNLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIMAFEIATGTRKPNRGLITPDKALLAIEKGFKERTKHPSLT
Protein: Chermesin D/asnovolin J monooxidase nvfH (EC 1.14.-.-) (Baeyer-Villiger monooxygenase nvfH) (Novofumigatonin biosynthesis cluster protein H) (A0A2I1BSU0)
Organism: Aspergillus novofumigatus (strain IBT 16806)
Function: Chermesin D/asnovolin J monooxidase; part of the gene cluster that mediates the biosynthesis of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety. The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase nvfA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations. DMOA is then converted to farnesyl-DMOA by the farnesyltransferase nvfB. Epoxydation by FAD-dependent monooxygenase nvfK, followed by a protonation-initiated cyclization catalyzed by the terpene cyclase nvfL leads to the production of asnavolin H. The short chain dehydrogenase nvfC then as a 3-OH dehydrogenase of asnovolin H to yield chemesin D. There are two branches to synthesize asnovolin A from chemesin D. In one branch, chemesin D undergoes Baeyer-Villiger oxidation by nvfH, methylation by nvfJ, and enoyl reduction by the nvfM D enoylreductase that reduces the double bond between C-5'and C-6', to form respectively asnovolin I, asnovolin K, and asnovolin A. In the other branch, the methylation precedes the Baeyer-Villiger oxidation and the enoyl reduction to yield asnovolin A via the asnovolin J intermediate. Asnovolin A is further converted to fumigatonoid A by the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfI that catalyzes an endoperoxidation reaction. The alpha/beta hydrolase nvfD then acts as an epimerase that converts fumigatonoid A to its C-5' epimer, which then undergoes spontaneous or nvfD-catalyzed lactonization. The following step utilizes the ketoreductase nvfG to produce fumigatonoid B. The dioxygenase nvfE further converts fumigatonoid B into fumigatonoid C. Finally the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfF catalyzes two rounds of oxidation to transform fumigatonoid C into the end product, novofumigatonin A.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDVTEIAEQTLNTSCLSPACQQQDYAEIEKRYEAERHQQLQTRGKIPDVNIRTNTRFEQFSKDPWLDDSNKRQQIQYHQRRHNGKHHKVLIIGAGYGGLLFAVRIIQTGAFTADDILMVDTSGGFGGTWYWNRYPGLMCDVESYIYMPLLEETGYMPRAKYASGPELRVHAERIADTWKLSNRAMFGVTVKSLDWDEVGKHWSARGLVLDYEKDQSKKASLHLSADFVMLASGIFASPKIPDFTSILEYHGHMFHTSRWDYGCTGGSPENPKLCKLGDKKVGIIGTGATAIQVVPHLAQYSKELHVFQRTPSAVDKRDNHPTDPVWWNKMLQSEGPGWQKRRMENFNAFTGNEQPQPAVDMIADGWTSMPSFSIIGGSPESNATDYLHRMKAFDFPRQERIRARVRETVHNKEVAEALSPWYPGWCKRPCFHDHYLAAFNRPNVRLIDVRQSGIDHFTPKGLVADGREHEIDVFVFSTGYTTSRSSPGGRADIAITGRNGLTMEHKWQNGLATLHGVITRDFPNLFFPGPSQAGTCLNHTYTLDQLATHVAYIISKTLIKIGAADAGYSPRVVIEPTKEAEEDWAVQVLARAATHGALSQCTPGYYNRDGMASAMKSLSMEDKMKLGRMVSWGEGIGSYMDQIVNWRGQGELRGLEIHCVD
Protein: DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 37 kDa polypeptide) (RNA polymerase III subunit C37) (P36121)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. The RPC53/RPC4-RPC37/RPC5 subcomplex is required for terminator recognition and reinitiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- DNA-directed RNA polymerase III subunit RPC9
- DNA-directed RNA polymerase III subunit RPC10
- DNA-directed RNA polymerase III subunit RPC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase III subunit RPC2
- DNA-directed RNA polymerase III subunit RPC4
- DNA-directed RNA polymerase III subunit RPC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase III subunit RPC6
Sequence:
MSIDNKLFVTEEDEEDRTQDRADVEDESNDIDMIADENGTNSAIANEQEEKSEEVKAEDDTGEEEEDDPVIEEFPLKISGEEESLHVFQYANRPRLVGRKPAEHPFISAARYKPKSHLWEIDIPLDEQAFYNKDKAESEWNGVNVQTLKGVGVENNGQYAAFVKDMQVYLVPIERVAQLKPFFKYIDDANVTRKQEDARRNPNPSSQRAQVVTMSVKSVNDPSQNRLTGSLLAHKVADEEANIELTWAEGTFEQFKDTIVKEAEDKTLVALEKQEDYIDNLV
Protein: RNase 3 (Ribonuclease like 4 precursor) (Ribonuclease-like 4) (A5HAK2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Ribonuclease T2,-like
- Odorant receptor, family D, subfamily 107, member 1.
Sequence:
MKTRQSFIILLLVICASLAVNSQSYNDFKRKHLAPAGMKEDDCTTLIVTERKIKEKNQCKKINTFILETEDKIKGVCNTPATDGKNHKGTGFTVINCTKIENIIDCKYNGVKRTTDIILTCENRLPVHYGRSNNS
Protein: Transposon Ty4-H Gag-Pol polyprotein (TY4A-TY4B) (Transposon Ty4 TYA-TYB polyprotein) [Includes: Capsid protein (CA); Ty4 protease (PR) (EC 3.4.23.-); Integrase (IN); Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4)] (P0C2J7)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.
Subcellular location: Cytoplasm. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MATPVRDETRNVIDDNISARIQSKVKTNDTVRQTPSSLRKVSIKDEQVKQYQRNLNRFKTILNGLKAEEEKLSETDDIQMLAEKLLKLGETIDKVENRIVDLVEKIQLLETNENNNILHEHIDATGTYYLFDTLTSTNKRFYPKDCVFDYRTNNVENIPILLNNFKKFIKKYQFDDVFENDIIEIDPRENEILCKIIKEGLGESLDIMNTNTTDIFRIIDGLKNKYRSLHGRDVRIRAWEKVLVDTTCRNSALLMNKLQKLVLMEKWIFSKCCQDCPNLKDYLQEAIMGTLHESLRNSVKQRLYNIPHNVGINHEEFLINTVIETVIDLSPIADDQIENSCMYCKSVFHCSINCKKKPNRELGLTRPISQKPIIYKVHRDNNNLSPVQNEQKSWNKTQKKSNKVYNSKKLVIIDTGSGVNITNDKTLLHNYEDSNRSTRFFGIGKNSSVSVKGYGYIKIKNGHNNTDNKCLLTYYVPEEESTIISCYDLAKKTKMVLSRKYTRLGNKIIKIKTKIVNGVIHVKMNELIERPSDDSKINAIKPTSSPGFKLNKRSITLEDAHKRMGHTGIQQIENSIKHNHYEESLDLIKEPNEFWCQTCKISKATKRNHYTGSMNNHSTDHEPGSSWCMDIFGPVSSSNADTKRYMLIMVDNNTRYCMTSTHFNKNAETILAQIRKNIQYVETQFDRKVREINSDRGTEFTNDQIEEYFISKGIHHILTSTQDHAANGRAERYIRTIVTDATTLLRQSNLRVKFWEYAVTSATNIRNCLEHKSTGKLPLKAISRQPVTVRLMSFLPFGEKGIIWNHNHKKLKPSGLPSIILCKDPNSYGYKFFIPSKNKIVTSDNYTIPNYTMDGRVRNTQNIYKSHQFSSHNDNEEDQIETVTNLCEALENYEDDNKPITRLEDLFTEEELSQIDSNAKYPSPSNNLEGDLDYVFSDVEESGDYDVESELSTTNTSISTDKNKILSNKDFNSELASTEISISEIDKKGLINTSHIDEDKYDEKVHRIPSIIQEKLVGSKNTIKINDENRISDRIRSKNIGSILNTGLSRCVDITDESITNKDESMHNAKPELIQEQFNKTNHETSFPKEGSIGTNVKFRNTDNEISLKTGDTSLPIKTLESINNHHSNDYSTNKVEKFEKENHHPPPIEDIVDMSDQTDMESNCQDGNNLKELKVTDKNVPTDNGTNVSPRLEQNIEASGSPVQTVNKSAFLNKEFSSLNMKRKRKRHDKNNSLTSYELERDKKRSKRNRVKLIPDNMETVSAQKIRAIYYNEAISKNPDLKEKHEYKQAYHKELQNLKDMKVFDVDVKYSRSEIPDNLIVPTNTIFTKKRNGIYKARIVCRGDTQSPDTYSVITTESLNHNHIKIFLMIANNRNMFMKTLDINHAFLYAKLEEEIYIPHPHDRRCVVKLNKALYGLKQSPKEWNDHLRQYLNGIGLKDNSYTPGLYQTEDKNLMIAVYVDDCVIAASNEQRLDEFINKLKSNFELKITGTLIDDVLDTDILGMDLVYNKRLGTIDLTLKSFINRMDKKYNEELKKIRKSSIPHMSTYKIDPKKDVLQMSEEEFRQGVLKLQQLLGELNYVRHKCRYDINFAVKKVARLVNYPHERVFYMIYKIIQYLVRYKDIGIHYDRDCNKDKKVIAITDASVGSEYDAQSRIGVILWYGMNIFNVYSNKSTNRCVSSTEAELHAIYEGYADSETLKVTLKELGEGDNNDIVMITDSKPAIQGLNRSYQQPKEKFTWIKTEIIKEKIKEKSIKLLKITGKGNIADLLTKPVSASDFKRFIQVLKNKITSQDILASTDY
Protein: Glucose receptor protein git3 (Glucose-insensitive transcription protein 3) (O94744)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Activates gpa2 when triggered by glucose and then activates adenylate cyclase.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Guanine nucleotide-binding protein alpha-2 subunit
- Adenylate cyclase
- cAMP-dependent protein kinase catalytic subunit
- Guanine nucleotide-binding protein subunit beta
- Glucose-insensitive transcription protein 7
- Guanine nucleotide-binding protein subunit gamma
- cAMP-dependent protein kinase regulatory subunit
- 3',5'-cyclic-nucleotide phosphodiesterase
- Polyubiquitin
- Serine/threonine-protein kinase sck1
Sequence:
MLHLDYTFNVSDATSTSSIIIVSRRELANLRIMVIIASAISIVFSLIAIFWRWSRRRTIREQFHIALFSVLFIRSIVQMIHPCLALSDPFFWAPKHRCFTIGFFLLVLVRMTDYWIFINILHNALLVLFPHVDTERRGLYRFRHTVFTLSFVIPLTIGGLAFTNKRNTFVNLQTRCYLPYTPVRFMFGLNWSFDYALSIAIIALQTCMFISIRRKIKRFKKYSHQQTNVFDTLNVIDSYPTAPDQVALPPFPDTNSTLTYTPSNSQSIYSSQSQPSPYSRPLLSSVHPNLPPGSQSTPANLNQSGIHFEQDFRDSPNRTNGLEDHTSFKLSSPLTSDEDGASSVLAAYGNDMQDDPLLKQRKRILSQSKFLFAYPAIFIFMWILPQIQIIVILAQPLHCSGSCKRFAFVAVFADNFVAIFIALSDFIWICYRGYTYLKERDSSKSYWDQIKELTLKWWRGKFGEEK
Protein: Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAP3K alpha protein kinase) (AtMAP3Kalpha) (F4HRJ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F2J10.10 protein
- 16S rRNA
Sequence:
MPTWWGRKSCKNKDDNHRGIISTDRDIKSSAVVVDPPLTPTRGGTPRCSREFAGASSAFSGFDSDSTEKKGHPLPRPLLSPVSIHHQDHVSGSTSGSTSVSSVSSSGSADDQSQLVASRGRGDVKFNVAAAPRSPERVSPKAATITTRPTSPRHQRLSGVVSLESSTGRNDDGRSSSECHPLPRPPTSPTSPSAVHGSRIGGGYETSPSGFSTWKKGKFLGSGTFGQVYLGFNSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQLCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLAYLHGRNTVHRDIKGANILVDPNGEIKLADFGMAKHVTAFSTMLSFKGSPYWMAPEVVMSQNGYTHAVDIWSLGCTILEMATSKPPWSQFEGVAAIFKIGNSKDTPEIPDHLSNDAKNFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVASTSLPKDFPPRSYDGNFSLQPTREPYPGRLSHDNYAKQPLSRTIKSPSRENVRAITSLPVSPCSSPLRQLGPAYKSCFLSPPHPSYAFPGQDSGYNLAEFAASPFRMKKDAMMEPSSFRTQTPNSPLRSRLV
Protein: EMBRYO SURROUNDING FACTOR 1.1 (Maternally expressed family protein 1.1) (Maternally expressed gene 1.1) (A8MSA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Maternally-contributed central cell peptide regulating suspensor development and correct auxin distribution in early developing embryos.
Interaction partners:
- EMBRYO SURROUNDING FACTOR 1-like protein 6
- At4g20420
- Similarity to tapetum-specific protein
- F-box associated ubiquitination effector family protein
- EMBRYO SURROUNDING FACTOR 1-like protein 8
- EMBRYO SURROUNDING FACTOR 1-like protein 10
- EMBRYO SURROUNDING FACTOR 1-like protein 9
- Uncharacterized protein AT4g11020
Sequence:
MKSSHTSLICILMLSLVALHQCVRMKVKEIGRSNKIYIPPCFRDSCDHVLKKDCYCCGSKPDLCWEDQHYCNTHCPPLKPLIN
Protein: Cytochrome P450 71B29 (EC 1.14.-.-) (Q9SAE4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAIILCFLILLPLILIFLKKLKHSKWKLPPGPPKLPFIGNLHQLQELPPRNLNHKYGPVILLRFGFVPLVVISSKEAAEEVLKIHDLECCSRPETAGTRKISYNFKDIGFAPYGEEWKAMRKLSVVELFTAKKHQYFRSIREEENDLLVKKLTELALTRSPVNLKKTLFTLVGSIVCRIGFGFNLHECEFIDENSISDLVDKSEILEMTSMFSDFFPGGIGRFIDWISGQNKRFDNVFSDLDTFFQNILDYHLKPGRKVADSSDIIDVVINMIKKQEKDGDSFKLTTDHLKGMISDIFLAGVSTSASTLIWAITELVRNRKVMKKVQEEIRTTLGDKKERITEQDLTNLHYFKLVVKEIFRLHPAVPFLLPRETLSHVKIQGYDIPAKTQIMINVYAIARDPKLWTNPDEFNPDRFLDSSIDYKGLNFELLPFGSGRRICPGMTMGITLVEFALLNLLYFFDWGLPEKEEADKIITGNGVAVGLVQVLLH
Protein: Nicotinate dehydrogenase medium molybdopterin subunit (NDH) (EC 1.17.1.5) (Nicotinic acid hydroxylase medium molybdopterin subunit) (NAH) (Q0QLF1)
Organism: Eubacterium barkeri (Clostridium barkeri)
Function: Catalyzes the hydroxylation of nicotinate to 6-hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs.
Interaction partners:
- Nicotinate dehydrogenase small FeS subunit
- Nicotinate dehydrogenase large molybdopterin subunit
- Nicotinate dehydrogenase FAD-subunit
- Carbon-monoxide dehydrogenase small subunit
- Carbon-monoxide dehydrogenase small subunit
- Carbon-monoxide dehydrogenase medium subunit
- Xanthine dehydrogenase FAD-binding subunit
- Xanthine dehydrogenase accessory factor
- 6-hydroxynicotinate reductase
- Selenium-dependent xanthine dehydrogenase
Sequence:
MKKRGKGVGSMWYGIGNTGLPNPAAAFVEIHGDGSANVMFGAADIGQGSGTAMAQIAAEELGLDYEKIHVTWGDTMVTPDGGATSASRQTLITGNAVILACRQAKETLAKTAAEKLDCAPEELSFRDNTVFITADPERSMTYGELMAAMKAAGRMAVGAGSYNPNTTGLAPENMSGIPFEVYSYATTIAEVEVDTETGEVDVLKVVSAHDVGTPINRSMVEGQIEGGVTMGQGFVLMEEIEVNTKNGAIKNPSMSKYIIPSNRDVPEIHSILVESEGGPGPFGAKGVGEPALIPMIPAVVAAIEDALGTRFTHTPIMPKDIVAAVKAQEK
Protein: Enterobactin synthase component B (EC 6.3.2.14) (Enterobactin biosynthesis bifunctional protein EntB) (Enterochelin synthase B) [Includes: Isochorismatase (EC 3.3.2.1) (2,3-dihydro-2,3-dihydroxybenzoate synthase) (Isochorismate lyase); Aryl carrier protein (ArCP)] (P0ADI4)
Organism: Escherichia coli (strain K12)
Function: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP). Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), the precursor of 2,3-dihydroxybenzoate (DHB). In the enterobactin assembly, EntB functions as an aryl carrier protein phosphopantetheinylated near the C terminus by EntD to yield holo-EntB, which is then acylated by EntE with 2,3-dihydroxybenzoyl-AMP to form DHB-holo-EntB. Then this product will serve in the formation of the amide bond between 2,3-dihydroxybenzoate (DHB) and L-serine.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10692387}.
Interaction partners:
- Enterobactin synthase component E
- Isochorismate synthase EntC
- Enterobactin synthase component F
- 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
- Enterobactin synthase component D
- Proofreading thioesterase EntH
- Enterobactin biosynthesis protein YbdZ
- Ferrienterobactin receptor
- Isochorismate synthase MenF
- Ferric enterobactin-binding periplasmic protein FepB
Sequence:
MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAALREVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK
Protein: Nuclear RNA export factor 7 (Nuclear export factor 7) (Nuclear mRNA export factor 7) (Q80SZ6)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
- mRNA export factor
- NTF2-related export protein 1
- NTF2-related export protein 2
- Aly/REF export factor 2
- THO complex subunit 4
- UPF3 regulator of nonsense transcripts homolog A
- UPF3 regulator of nonsense transcripts homolog B
- Predicted gene 4340.
- THO complex subunit 5 homolog
- Eukaryotic initiation factor 4A-III
Sequence:
MCSNERKQGSFRYTGTTNAWQSPMGRKKDRVSSLSYAGKRTDHYEHTGHTILPFKAQSDGGNLEMRAVLWNPSVRHTPYVGQHRSREEEHMEDQIHVTAQRDDKPEQREAGQFTEDGELGSWFKVTVPCGRKYDKTQLMNSIHSLCSVPFTPVDFHCDKHRIQFFVPDFRIASALKDISYKIHNEYFQKIPIFVNPSVAPYSVQNRFTKEEMEQLKLAMRKRYDVSQHALCLKKLRFDPDLMKNNIHMILNHRSCMAATLQIIQENFPKLLSLNLSSNKLFQLDSLIDVVKKAPQLKILNLSKNMLRTVWELEKMKGLKLEQLWLEGNPLCSTFPDRSSYIRAVLECFPELSYLDGRKLLLPTVMNTQERKLMKPCKDIFMGSEVIKNQVHRFLREYYLMYDSEERQGLLNIYHDQACFSLTIPFNPNDPDLNSMYVYFKDENDMKNFKEFHIQRQLLKYTKQDIVECLRGFPQTLHAFSSFQVNICFQMETMLCFSVCGLFKEEGTPKECVRAFMRIFIALLGSSNMYIVNDQLFVRNPSSEEINSAFVIPSPTSYSNFKLVLSQEQQRMVQAFSTQSGMKLEWSQKCLEDNKWDYARAAEVFTMLQTKCKIPKEFFKQ
Protein: Protein alcS (Q460G9)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cell membrane {ECO:0000269|PubMed:16531087}; Multi-pass membrane protein {ECO:0000269|PubMed:16531087}. Cell septum {ECO:0000269|PubMed:16531087}.
Interaction partners:
Sequence:
MTTEISNGEAKGHHLSTIPSSITLSAEQFEKLYLSPMMRQQPSLARKVGNPTPLALGGFVITTTPLSCCLMAWRGSSGNGIAFIGPIIFLGGLLLLITSILEFILGNTFPCVVFGTIGGFWFAFAATMIPSFNAAAPYSSSATSTTAGLTSASFMNTYAFLFITMAVLMLIFLLCATRTNVVYTLIFLSLLLVFLLLSAGYWRLGEGDAAVGDRCIKGAGASLFVASLLGFYLLIAQLFDAVGLPITLPVGDMERFWPRSQK
Protein: 6'''-hydroxyparomomycin C oxidase (EC 1.1.3.-) (Lividomycin biosynthesis protein Q) (Q2MF66)
Organism: Streptomyces lividus
Function: Glucosaminyl-6'-oxidase involved in the biosynthetic pathway of lividomycin by mediating FAD-dependent dehydrogenation of 6'''-hydroxyparomomycin to paromomycin.
Interaction partners:
Sequence:
MERLRGPSPLENTTARHPAPLGPAHRDGLEPGTADRVWDVCVIGSGASGAVAADRLVRQGLDVLMVEEGFRLAPHVGLDEAESLSRQALARDGEGNWTDEGWPWTTSNLGGGTVYYGGASFRYRPFDFDPGELVHTDGVDVRWPYTLADLVPYYEVLERRLGVCGGDAPGIHRGSRHSRGPAHQPSPAARVLRAAGESLGYRPFPTPLAINRDPHGGRAACARDSLCVSHLCPTGAKGDVVAVFLAPLAAHPNFALRTGVRALRLEQDRSGEVAAVRCLDRQTGQAHRVRARVYVVACNAIQSAALLLRSRTPYSPDGVGNHSHLVGRGLCMKLSEYLSGTVDADPAVLADPYTNTGPFSTVAFLDHYLDPDCPGGFGGLIYESKRDQRHKLVHDALELRIETILADHPNLDNRVGLSTHLDEDGMPAVVIDYTPDPRDLDRLRYMTGRCERLLRTAGARGIRSRSTGFAQGSSHLHGTCRAGHDPARSVVDAWGRVHSADNVYIVDGSFMPYPGGLNPTLTIQAHALRTSRAIASHLAADRAAHV
Protein: 14-3-3-like protein (A1XJ43)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MEKEREQQVYLARLAEQAERYDEMVEAMKSVAKLDVELTVEERNLLSVGYKNVIGARRASWRILSSIEQKEEAKGNEQNVKRIKDYRQRVEDELSKICNDILSVIDKHLIPSSSTGESTVFYYKMKGDYFRYLAEFKAGDDRKEAADQSLKAYEAATSTASSDLPPTHPIRLGLALNFSVFYYEILNSPERACHLAKQAFDEAIAELDSLNEESYKDSTLIMQLLRDNLTLWTSDLPEEGGEQSKADEPQAES
Protein: Metal uptake regulation protein (Q9L2H5)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Metal transport ABC transporter
- DNA-directed RNA polymerase subunit alpha
- Metal transport ABC transporter
- ABC-transporter metal-binding lipoprotein
- RNA polymerase principal sigma factor HrdB
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit beta'
- DNA-directed RNA polymerase subunit omega
- Fe regulatory protein
Sequence:
MTTAGPPVKGRATRQRAAVSAALQEVEEFRSAQELHDMLKHKGDAVGLTTVYRTLQSLADAGEVDVLRTAEGESVYRRCSTGDHHHHLVCRACGKAVEVEGPAVEKWAEAIAAEHGYVNVAHTVEIFGTCADCAGASGG
Protein: Non-structural protein V (Q77M19)
Organism: Measles virus (strain Edmonston-Schwarz vaccine) (MeV) (Subacute sclerose panencephalitis virus)
Subcellular location: Host cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MAEEQARHVKNGLECIRALKAEPIGSLAIEEAMAAWSEISDNPGQERATCREEKAGSSGLSKPCLSAIGSTEGGAPRIRGQGPGESDDDAETLGIPPRNLQASSTGLQCYYVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSGGDNESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLRLQSRGNNFPKLGKTLNVPPPPDPGRASTSGTPIKKGHRREISLIWNGDRVFIDRWCNPMCSKVTLGTIRARCTCGECPRVCEQCRTDTGVDTRIWYHNLPEIPE
Protein: GH12235p (Putative potassium channel subunit homolog) (Seizure potassium channel) (Seizure, isoform A) (Seizure, isoform B) (Seizure, isoform C) (Q7JPB9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- KCNQ potassium channel, isoform F
- Potassium voltage-gated channel protein Shab
- Calcium-activated potassium channel slowpoke
- Potassium voltage-gated channel protein Shal
Sequence:
MSHKSCVELSEIRKLDKIVQQCELYMSNNNINDNAAKKPPVKEFKRNCPAKSNKFVERELFSLMCNLNKIEKKQVFVSDILINASMFDDKKESLARFPKNVSDHNTLVYHKFLRTRPTNDDEALKLKAGGKSKERPGTKITADCFFSPLLFKINNKRECLKKVKPMKGENAVETNGIPLESKPSQHKKQKSFKKCIKCDKKKLYIKNYQVSARRECDLLCSYDPLRKNNADLFQTHKGTSYECMFKNLKYNQAEKPTDNVMGNSYDDMLDKEALLGSKSEPKGQDPNDMITSLGGNILLDQKLQNNYYHKWTLLHYSPFKAVWDWIILILVMYTAIFTPYVAAFLLGEQDYQRRNSKYINSDPIVIIDLIVDVTFIVDIIINFRTTFVNSQDEVVSHPGRIAVHYLSGWFLIDLVAAVPFDLLLVGSDTDETTTLIGLLKTARLLRLVRVARKIDRYSEYGAAVLILLMATFILIAHWLACIWYAIGNAEKSIASKNIGWLNSLAYDIQEPYFDNRTGGPSIKSRYITALYFTFTSLTSVGFGNVAPNTDAEKAFTICVMLVGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNSLLKGFPECLQADICLHLNRKLLTTCAAFSEASPGCLRAFSLKFKTTHAPPGDILVHRGDVLTSLYFIARGSIEIQRAGNIVVLGKNDIFGENPCIYPTVGKSNGVVRALTYCDIHKLHRDDLLDVLDSYPEFLESFVSNLVITYNMRDDEHSGVDIKHRYLRAKSSDKMRSSPDIPSIRIVGLRYKKQNVNTSVHKVKNDNSRDLNIFIENEIANYHLDLFDNNN
Protein: Ligand-dependent nuclear receptor-interacting factor 1 (HP1-binding protein enriched in inactive X chromosome protein 1) (HBiX1) (Receptor-interacting factor 1) (Q5T3J3)
Organism: Homo sapiens (Human)
Function: Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases. Also required for silencing of the DUX4 locus in somatic cells.
Subcellular location: Chromosome {ECO:0000269|PubMed:23542155}. Nucleus matrix {ECO:0000269|PubMed:17455211}. Note=Localizes to Barr body; recruited by SMCHD1. {ECO:0000269|PubMed:23542155}.
Interaction partners:
- Structural maintenance of chromosomes flexible hinge domain-containing protein 1
- Chromobox protein homolog 3
- Chromobox protein homolog 5
Sequence:
MSNNLRRVFLKPAEENSGNASRCVSGCMYQVVQTIGSDGKNLLQLLPIPKSSGNLIPLVQSSVMSDALKGNTGKPVQVTFQTQISSSSTSASVQLPIFQPASSSNYFLTRTVDTSEKGRVTSVGTGNFSSSVSKVQSHGVKIDGLTMQTFAVPPSTQKDSSFIVVNTQSLPVTVKSPVLPSGHHLQIPAHAEVKSVPASSLPPSVQQKILATATTSTSGMVEASQMPTVIYVSPVNTVKNVVTKNFQNIYPKPVTEIAKPVILNTTQIPKNVATETQLKGGQHSQAAPVKWIFQDNLQPFTPSLVPVKSSNNVASKILKTFVDRKNLGDNTINMPPLSTIDPSGTRSKNMPIKDNALVMFNGKVYLLAKKGTDVLPSQIDQQNSVSPDTPVRKDTLQTVSSSPVTEISREVVNIVLAKSKSSQMETKSLSNTQLASMANLRAEKNKVEKPSPSTTNPHMNQSSNYLKQSKTLFTNPIFPVGFSTGHNAPRKVTAVIYARKGSVLQSIEKISSSVDATTVTSQQCVFRDQEPKIHNEMASTSDKGAQGRNDKKDSQGRSNKALHLKSDAEFKKIFGLTKDLRVCLTRIPDHLTSGEGFDSFSSLVKSGTYKETEFMVKEGERKQQNFDKKRKAKTNKKMDHIKKRKTENAYNAIINGEANVTGSQLLSSILPTSDVSQHNILTSHSKTRQEKRTEMEYYTHEKQEKGTLNSNAAYEQSHFFNKNYTEDIFPVTPPELEETIRDEKIRRLKQVLREKEAALEEMRKKMHQK
Protein: Type III effector protein AvrPto1 (Q87Y16)
Organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Interaction partners:
Sequence:
MGNICVGGSRMAHQVNSPDRVSNNSGDEDNVTSSQLLSVRHQLAESAGVPRDQHEFVSNQAPQSLRNRYNNLYSHTQRTLDMADMQHRYMTGASGINPGMLPHENVDDMRSAITDWSDMREALQYAMGIHADIPPSPERFVATMNPNGSIRMSTLSPSPYRNWQ