wanglab/gogpt-training-data huggingface dataset:
Protein: MotD (G3XD90)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
- MotC
- Chemotaxis protein MotA
- Flagellar motor switch protein FliG
- Flagellar basal-body rod protein FlgC
- Protein phosphatase CheZ
- Chemotaxis protein MotB
- B-type flagellin
- Flagellar biosynthesis protein FlhA
- B-type flagellar hook-associated protein 2
- Flagellum-specific ATP synthase
Sequence:
MQRRRRHQEEHENHERWLVSYADFITLLFAFFVVMYSISSINEGKYKILSETLTGVFNQPDRSLKPIPIGDERPRTTEPERTSVEEQPSDNAASADSLERIADSVRDAFGDLIASDQLSVRGNELWIEITLNSSLLFPSGDALPNDAAFDIVEKVAKILAPYKNPIHVEGFTDDVPIHSPRYPTNWELSAARAASIVRLLGNDGVEPSRMAAVGYGEFQPVADNASAEGRAKNRRVVLVISRNLEVRRSVSGVGSGKAQPDSALRHAGSAAGTQAADTGGTPAPAPATVNSPSPSP
Protein: 2-pyrone-4,6-dicarbaxylate hydrolase (PDC hydrolase) (EC 3.1.1.57) (2-pyrone-4,6-dicarboxylate lactonase) (Q93PS7)
Organism: Comamonas testosteroni (Pseudomonas testosteroni)
Function: Involved in the degradation of aromatic compounds via the protocatechuate 4,5-cleavage pathway. Catalyzes the hydrolysis of 2-pyrone-4,6-dicarboxylate (PDC) to oxalomesaconate (OMA). Also catalyzes the reverse reaction.
Interaction partners:
Sequence:
MSQFEKTPGWLDWYANPSKPQFKLPAGAVDAHCHVFGPGNEFPFAPERKYTPCDASKAQLYALRDHLGFARNVVVQATCHGADNRAMVDACKSSGGKARGVATVKRSISDAELQQLHDAGVRGVRFNFVKRLVDFTPKDELMEIAGRIAKLGWHVVIYFEAVDLPELWDFFTALPTTVVVDHMGRPDVTKGVDSEEFALFLKFMREHQNVWSKVSCPERLSVTGPKALNGEQNAYRDVVPFARRVVEEFPDRVLWGTDWPHPNLKDHMPDDGLLVDFIPHIAPTAELQQKLLVDNPMRLYWPEEV
Protein: Presequence protease, mitochondrial (PreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase) (O42908)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity). Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity). Also degrades other unstructured peptides (By similarity). May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
Subcellular location: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:P32898}. Mitochondrion matrix {ECO:0000250|UniProtKB:P32898}.
Interaction partners:
- Vacuolar protein sorting/targeting protein 10
Sequence:
MNYAKLSIAFSKKTIKTHNCRLFQRWLHVGDKVHDFRVVDTKKVPELQLNYTRLKHEPTNADMIHLDREDPNSVFSIGFQTPAENDEGIPHILEHTTLCGSNKYPVRDPFFKMLNRSLATFMNAFTASDFTFYPFATVNTTDYKNLRDVYLDATLFPKLRKLDFLQEGWRFEHADVNDKKSPIIFNGVVYNEMKGQVSDSSYIFYMLFQQHLFQGTAYGFNSGGDPLAIPDLKYEELVKFHRSHYHPSNAKILSYGSFPLEDNLSALSETFRPFSKRELNLPNTFLKEFDQEKRVVEYGPLDPVMAPGRQVKTSISFLANDTSNVYETFALKVLSKLCFDGFSSPFYKALIESGLGTDFAPNSGYDSTTKRGIFSVGLEGASEESLAKIENLVYSIFNDLALKGFENEKLEAILHQMEISLKHKSAHFGIGLAQSLPFNWFNGADPADWLSFNKQIEWLKQKNSDGKLFQKLIKKYILENKSRFVFTMLPSSTFPQRLQEAEAKKLQERTSKLTDEDIAEIEKTSVKLLEAQSTPADTSCLPTLSVSDIPETIDETKLKFLDIAGMKAQWYDLAAGLTYIRLLLPLKNFPESLIPYLPVYCDACLNLGTHSESIGDLEHQIRRYTGGISISPSAVTNNSDVSKYELGIAISGYALDKNVGKLVELINKAFWNTNLSNTDKLAIMLKTSVSGITDGIAEKGHSFAKVSSASGLTEKTSITEQLGGLTQVKLLSQLSREESFGPLVEKLTAIREILRGTSGFKAAINASPTQHEVVEKALQKFMKSRGVNQQTQTKSTSKERNGINSIKTYHELPFQTYFAAKSCLGVPYTHPDGAPLQILSSLLTHKYLHGEIREKGGAYGAGLSYSGIDGVLSFFTYRDSDPIRSLSVFDEASEWATTHEFSQRDIDEAKLAVFQGIDSPVSESQKGMLYFVDGVTDEMLQNRRKQLLNVSANDLKAVAKKYLVNPKKSYTAVLGPKSEKQLPTWVIDKFES
Protein: Protocadherin gamma A5 (Protocadherin gamma subfamily A, 5) (Q91XY3)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MADPPRRWICNDLLTFFMLLGTLCAPGKGQIRYSVREELDKGSFVGNISKDLGLEPRELAERGVRIISRGRSQLFSLNPRGGSLVTAGRIDREELCVQSSPCLVSFNILVENKMKIYGVEVEILDINDNFPRFRDEELKVKVNENAAAGTRLVLPFARDGDVGVNSLQGYKLSSNRHFSLDVKSGSDGQKHPELVLEQPLDREKESAHDLVLTALDGGNPVLSSTVHISVTVLDANDNAPLFTQSEYRVSVPENTPVGTRLLTLTATDADEGINAKLTFSFRNEEDKISETFQLDSNLGEISTIQSLDYEESRFYLMEVVAQDGGALLASAKVLVTVQDVNDNAPEVILTSLTSSVSEDCLPGTIIALFSVHDADSGENGEISCSIPKNLPFKLEKSVDNYYHLLTTRALDREETSDYNITVTVVDRGTPPLSTENHISLKVADINDNPPTFSRPFYSTSISENNPRGVSIFSVYAYDADSGDNAQVTYSLAENTFQEVPVSSYVSINSDTGVLYALQSFDYEHLRDLQLLVTAKDSGTPPLSSNVSMSLFVLDQNDNIPEILYPTIPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFSIGLHTGEVCTARALLDRDVLKQSLVVAVQDHGQPPLSATVTLTIAVGDSIPDVLTDLGNHNTLAEPQDSDLTLYLVVSVAVVSCVFLGFVTVLLALRLRHWHMSRLLQTSTGRLADMPASHFVGMDGVQAYLQTYSHEISLTTDSKKSHLIFPQPNYADRLISEESCEKSEPLLIPHNIHTHKEEPGDAQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Protein: Protein SKG3 (Suppressor of lethality of KEX2-GAS1 double null mutant protein 3) (Q06315)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May play a role in cell wall integrity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Bud neck {ECO:0000269|PubMed:14562095}. Cell membrane {ECO:0000269|PubMed:14562095}; Peripheral membrane protein {ECO:0000269|PubMed:14562095}; Cytoplasmic side {ECO:0000269|PubMed:14562095}.
Interaction partners:
- CCR4-NOT transcriptional complex subunit CAF120
- UPF0508 protein YJR030C
Sequence:
MKRIFSGVKSPKLSAPPKVFKNDESPSTPSSPKFDQGLRSLSASASRLFSNSISTPGSPTLDLPQEHSINGDISPELVPIVTLLSAQAHRRYHYGIFLILHDLKTDGTPAARQWEECYGVLLGTQLALWDAKELSDSKNNKNTSTMKKAASRPSFINFTDASVRSLDANDQVIIASENEKTKKDLDNVLVVSTTLKNRYFLKFKNSKSFKTWNAAIRLSLFEFTALQEAYTGSFLSSRGVKLGDIKVVMADTKFTYEDWVSVRFGTGMPWKRCYAVISPQSGKKKKNSKGSICFYENNKKTKKSNIMTTVVDARALYAVYPSSPILIDTSTIIKLEGFVSFDKSEEPQETNLFIMPEKHQGVPGYDTIIRFLIPAMNAFYLYGRPKGLIANRTDPDSLLFALPTLPHIYYLQVDDVLSLTKDKNYIHWSAADWRNNIVQVLQKKLSKGYKGCGNKTVSVSSGMMKSPAISSAELFEGYDSLPERQMESPQKSKMKSPTLASTDDINSASASVNSHATSVKQTELFVTDNSSKINDSVSAQSSVTTNFKDTFTTPMTSGMLNHENSERSFGSGLKLKITDSNLENMEDVEAKSANEFSTTPEDKHIHLANAAELSALYDKYSTSPFGKSEANSSPKPQKLEVKDRSKNENRSPYERYVGTSAESKTFEIGNVRESKSTINTSLSSPLRVEDSRRSKNEDLGSLKEFEELSQKISNMGMANISSEALSDTAENSSFVTDLNLNINNSSSVNLNEEQRVPDFGEENVFDPDYMEQNQMLETESRYTTDEFDFSDNQDAASSNYSNGQTNRTVTETLSASDRNDKIPHSSLFTNLNQLTSNGGNYQDREDFSGDQINKPQQSQPLHVKGPQTSSFGYRNSSANSSQPQAPYPVGRPLGKIRTGPLTVQPMQQGGNSSMYSFQSSQHRFHSSQQRQNQSLSFRNNTYGSGNNQNTFHPSPQLQQQPQNMRYLNNKLPINDRSPIPQTQHHVPDGRPSLHINTTNRTNPLTAQSGFSQFMPPNSTSTNPYSS
Protein: Metalloendopeptidase (EC 3.4.24.-) (B5X7S6)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MAPVFVLSIFIAVLCSVQGRSTGKVSFERSEEDMEIDGTSANSIEEDEYSASTLIEKANRNLGQRPDEPLVMFGDIAVYTGFMNADPCTARGCKWQKSSDGNVYVPFVISNEYSARERSVIEGGLRTFAASTCIRFFPRTNQRDFVDIQSQSGCFSFIGRRGNGQVVSLSRNGCVFLSVVQHELLHALGFNHEQTRSDRDSNVQILFQNIMPGMEFNFRKINTINLGTPYDYNSVMHYSRFAFSRNRQPTILPIPDNNAVIGRATEMSPIDILRINRLYNCTGQQLD
Protein: Variant surface glycoprotein (VSG), putative (Q380Y1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MRLISLAVAAFIVLRSTKPANIADAANKEEHAALCNFISMAGRVIAVPTVPLLDTASYDYIQQLNFALGDQQWQEKFYKKSDKKEVKNTAAEAGITGEGAADMWADLKKAAEAMKSDSQNPLLKEIEEMKLTAAARRLAKAELESLENESRALKKMYPAPPKNVDYENNNPKSKLLAALLGAGNADVGTATGQKAVGAEATDTRQATCTAGEKTTARPASALAMLACVCQSSGTAVTNFICTEKAKDSNAWTANAYPHDTGLQHIGKSCPKPRTAPITKAELEAALNNLQALIHADGTNGYLGAYVQTGCDGTSPNGICVQFPGIAATNPDVATKTTWLSDVTAIITNLKILEHNQAKAEYVNNQIKAKKHQALAALRRSKAIAVAVQVPTPQTAQQPQIDVNTRCEAHNKSKTACLGAKCAWKGQKDDDGPCTRSEQQAAEEEKQTAGEAVTGTETEKCKGKGEKDCKSPDCKWEINACKYSSFLVNKKFNLIMAASFESFL
Protein: Transmembrane protein (Q24328)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQHQQQQQQQQQQQQHKQVRYRNLRRNVEIGAKKIWLPLIIFLSLQVALVCADDVEVVKAIAGGPDDELTIALGDHENELDQMAQESEQEQQAQAQQQQQQQQQQQQQQQQQQHQQLPQIQMQLPQSVPKVQVHYQHNMPQPPPNVALTMRNNHQNIPLSFGQPFGPPPPPGAQFYKGPPPPQLQQRPQPPPQLQLQVQPQQQQQQQQQHTQQQGQQQQVQVPDLSVGGSSNNEIWAAPVQDMPKIVSLDVKCEKNGMKVFVQFDKPFNGIVFSKGHYSNMNCVHLPSGLGRSSASFDIGLHECGTAGNTDNYGQGYGHEAGSTGAGTYFENIIVIQYDPQVQEVWDQARKLRCTWHDQYEKSVTFRPFPVDMLDVVRADFAGDNVGCWMQIQVGKGPWASEVSGLVKIGQTMTMVLAIKDDDSKFDMLVRNCVAHDGKRAPIQLVDQRGCVTRPKLMSRFTKIKNFGASASVLSYAHFQAFKFPDSMEVHFQCTIQICRYHCPEQCSAETNLQDVHHLQVGPESQYGPPPQLHVDAYHVASAIGKRRDERRVQRRARAVAEPQVGLNRIIKVVSSGDLTFAIDDQAGGNGSSTNGANSGVDRSPQTMVFPLREEGQICMTTPGFAITLIVLLGILVTSCLTSAVLYVRLRPFSSFAGSAKERAVAFTNPQLAPLPVIQLPSPADLQGTLSKKRAMS
Protein: Tetratricopeptide repeat protein 33 (TPR repeat protein 33) (Osmosis-responsive factor) (Q6PID6)
Organism: Homo sapiens (Human)
Interaction partners:
- Superkiller complex protein 8
- Coiled-coil domain-containing protein 97
- PHD finger-like domain-containing protein 5A
Sequence:
MASFGWKRKIGEKVSKVTSQQFEAEAADEKDVVDNDEGNWLHAIKRRKEILLEGCAEKSKQLKDEGASLAENKRYREAIQKWDEALQLTPNDATLYEMKSQVLMSLHEMFPAVHAAEMAVQQNPHSWESWQTLGRAQLGLGEIILAIRSFQVALHIYPMNPEIWKEDLSWARTLQEQQKVAQRIKKSEAPAEVTHFSPKSIPDYDFESDEIVAVCAAIAEKEKTVSANKTMVIVSASGAIETVTEKEDGATPPDGSVFIKAR
Protein: ATP-dependent DEAD/H RNA helicase, putative (Q582X2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNasePH-like protein exosome-associated protein 1 Rrp42 homologue
- Exosome component CSL4
- Ribosomal RNA processing protein 4
- Ribosomal RNA processing protein 45
- Ribosomal RNA-processing protein 43
- Exosome complex exonuclease RRP40
- TOG domain-containing protein
- Telomerase-associated protein, putative
- Probable eukaryotic initiation factor 4A
- Small ribosomal subunit protein uS5
Sequence:
MATQQRDLNLLFGNCLKDDDFLKIPMDTVGALQAIFEAKNIPIQEEADASYEGKIAQVARRRSALSRVCDAVLSAFRNGGKPPAGGIVGTLKHEEEERNAWKFLVAAVQKDGKMRAVIEEELLRTAVEHHYATARPELCDMFAHLAATEMFFIDGDSLFMSALSPPNVDWDLIQPLHVMYNAQKLLFDMECRGARFHIVFFDSMLWMWERAPAKMLMRENLRLALTAASECPGGSRFTVRTFPSFHSEAFETYLKEWEPEFIFMSDGEQLGSLNPLQEFFVNPEVETTNASSGVNSSGAVAVPARRPYRSIVEDEEIGNDAAMYIRCLLLWAASRRLKVAYSSRVIYRENSMIVFTMGVDGSTLERSLGIEPEVRALAQSLEREVTLPTLSQKSLNVLNEDLTFREKIVCSAVRTYLTMKERSEQEQQLCQALVITAYIVGILSCEARAQAALPSAVLQNFIADISPFLLSALRHAGCDNGGGQVFDIIDGHLLYAVARLLREEAPSHLLDEDGVGDISMTWQYLMDDDTLDITSTPFRSLPELAQPQPVQLQEYPYLKHELVEHLAKTFKVEGHKAKRPIPDGYGAANELIGWDITTPFDKFNDVTDADGEREAKIHMTEKEARHAQEFQTKFVRNAFQQAQSMGISGFAAQPLTLVCSDNEQESTDAAGSGGAGGCGKGAAAKKKKGNNEHEGQRNKKGRSKDDEIREQKNLKDAASSIQSWLKQMDDHLRSIDPTHGRTTNKDRDDAVKKLLAAVKRLAEAKFTKGFEPDRTIGKSEGSDISLKISMWRLLVASSGLREAEFALTLEDPSAKNRAVKKKGLKTETAVPYGFTVIDNLVATISDKSTEWGELEGLRKFKSDITSAEAASYLRWVYLSYVELHIQMKIKCFVVKLRLENWRSERERARLAKETPDLSVAIPLFLYCHHHVLSVVQNEGLQISQEDLDTVRSALRHLDFGEDYYSKLDRAITQWQNKAPSLLGPTMLPRMRQLTDTPEMMQLIHMGHLLERPVIRRPDYRVAFNPDSWQRELLDIVDNRGSAVVCAPTSAGKTFVSYYCMYNTLRRSNRRIVVYLAPARALINQAVADVCARYGSKEYKNSGKYIYGVLGGADYHQFHDSCQVLLTVPETFETMLLSPKYAEWVDLIDYVILDEIHSMESNGNGDVWERILALLPCPFVALSATLGETQQLCGWLNRVQSRLKEQAVDTPAKARDYRVHVLPSEGQTIQRWNDIKKYIYLPPPDTRTSLKKLTTTYENRYIHDLHPLSILTTDQLQRGFPPDITLVPSEVVSLFGEMRTAFDNIIWPKLSSIPRVQMLQSKLKLLEPGRYFEADLYITQQRARLYEREVKDAFAQWVLLSNSSVKKPDISSDEQVKEFNSTMKHATETILAAFAQKLNEKEAALGSYAVAAMERKRAQQQSRTNTEGRSEQESDEAVPEAAFPGSRQFIREQSLNVLREISARDMGPAIVFSFESEDCEDLVKYVVEQLEEAEERYRQTEEFALYKAKVERAAAEREARHKQRESTLKQKRLRTNEDGEVERAERDVDEGEEDEGEVCEVPDILPEFTFIGAGCSVEPDVVKELIKDCEGEGEDLLLRALKRGIGMHHAGVKGKLRGHVERLFRGRHCGVIFSTETLALGIHSPCRSVVLAGDHILLNPTQFRQMMGRAGRRGLDHLGHLIFLGITMQRIKRLMTSGMTVIKGNVQMDPISQLRLLQLYDYNTHRSLKHEDAWKQHVKKLAERLFVNPLFFQRREAFAQSNMEGFTIEYLQMLLVFLQKQGLHFRDRPSSLGSLLQDVMYVFREAHVGNEGFAFIRMLTSGVFHEAHYPPALDKELHSGVTDEPIAELLAYLFSFHQTCGVPLEIHRSALLDPAVSVVWEGKTNATQHRVVLSPVDVCSPSVRPFDNTEFFALLSAFYNQLASRLDEKKEKEEKGKEQEEEEEEESSEGPRLPYVETGGDQLIFGNGAGDFPLMDALKESAVQFKARHPFVAISGCGDVFTSVDEVVFSLRDDLFCDRRLLPVLDVSDGWRHDGAQVLINACLADFLRVKAQIDTTRKNYRFTMLEELNGLSQSLSYSVLNRAEKLISNLAGLVRKAHLPAASILTAIMPDESFTAQEEGYSAGAPRLLKVAERLNSLQLQIQKRFAEEKYAAKKAKWVSELAAKRNEQK
Protein: CNMamide receptor (FI04552p) (Q9VT27)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- CNMamide, isoform B
- Thyrotropin-releasing hormone receptor
Sequence:
MDMEYITSSSGNITATTEADFSSSLGESNVTEYNTTEMDANESAGEDEEMLRIAFFIGHFVHQYYIPVLCCTGSIGNILSVFVFFRTKLRKLSSSFYLAALAVSDTCFLAGLFAQWLNFLNVDIYNQNYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTLVGCLHCLPYIVIAKPVFMPKLNTTICDLNSEYKEQLALFNYWDTIVVYAVPFTTIAVLNTCTGCTVWKFATVRRTLTMHKMKPQTNSMPSNSSNSSGGASSAVASYRLSASLKRQKSTGTHPSGQHNVANRQTDDQEQQQQSQQHQINNCQHHCEITQKPARRKVQNSSQLKVTKMLLIVSTVFVCLNLPSCLLRIEAYWETESARNQNSTIALQYIFHAFFITNFGINFVLYCVSGQNFRKAVLSIFRRVSSAQREAGNTQVTVSEYCRNTGTSTRRRMMTQHCWNEMHELHPLK
Protein: Sperm acrosome membrane-associated protein 1 (D5K8A9)
Organism: Sus scrofa (Pig)
Function: Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane {ECO:0000269|PubMed:18448843}; Single-pass type I membrane protein {ECO:0000305}. Note=Primarily found in the equatorial segment of the acrosome (PubMed:18448843). The tyrosine phosphorylated protein localizes to a smaller region within the equatorial segment (PubMed:18448843). Also expressed weakly in the principal segment (By similarity). {ECO:0000250|UniProtKB:Q9HBV2, ECO:0000269|PubMed:18448843}.
Interaction partners:
- Serine rich single-pass membrane protein 1.
- Dpy-19 like 2
- Zona pellucida-binding protein 1
- Uncharacterized protein
- Spermatogenesis-associated protein 16
- Major seminal plasma glycoprotein PSP-I
- Coiled-coil domain containing 62
- Testis-specific serine/threonine-protein kinase 4
- Anaphase promoting complex subunit 16.
- Izumo sperm-oocyte fusion 1
Sequence:
MSPGGAGCSAGLLLTVGWLLLAGLQSTCGINVTAVQDPSLVSEGENEGEEEAENDSEVENEPQAEAEQDVSNKTVVKEVEFGMCTVTCGVGIREVLLTNGCPGGESKCIVRVEECRGPVDCGWGKPISENLESVRLSCVHTSPVNRFKYVWRLLRPNQQAVILANDSAILEVQRETHPMAFQCETLDNNEIVATVKFTVYTTAELQMKRSSRPDTDAVLVFVLTIGVIICIFVIFVLIFIIVNWATVKDFWASKASTTEIQSELSSMKYKDSTSLDQSPTEIPGHEDDALSEWNE
Protein: Radixin (A0A0G2K095)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cell projection {ECO:0000256|ARBA:ARBA00004316}.
Interaction partners:
Sequence:
APSPGVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTMKAQKELEEQTRKALELEQERQRAKEEAERLDRERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMCAPPPPPPPAVVPPTENEHDEQDEHSAEASAELSSEGVTNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM
Protein: Transcription factor JunD (Transcription factor AP-1 subunit JunD) (P17535)
Organism: Homo sapiens (Human)
Function: Transcription factor binding AP-1 sites. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 3'-TGA[GC]TCA-5' and enhancing their transcriptional activity.
Subcellular location: Nucleus.
Interaction partners:
- Fos-related antigen 1
- Transcription factor JunB
- Transcription factor Jun
- Protein c-Fos
- Protein FosB
- Fos-related antigen 2
- Menin
- Mitogen-activated protein kinase 8
- Cyclic AMP-dependent transcription factor ATF-3
- Mitogen-activated protein kinase 9
Sequence:
METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAAALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSSQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPGELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALKDEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY
Protein: Protein AATF (Apoptosis-antagonizing transcription factor) (Q9QYW0)
Organism: Rattus norvegicus (Rat)
Function: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. May negatively regulate the pro-apoptotic activity of DAPK3/ZIPK. Can act cooperatively with TSG101 to stimulate AR mediated transcription activation (By similarity). May negatively regulate the pro-apoptotic activity of DAPK3/ZIPK. Can act cooperatively with TSG101 to stimulate AR mediated transcription activation.
Subcellular location: Nucleus {ECO:0000269|PubMed:10580117}.
Interaction partners:
- UTP14A small subunit processome component
- NOP14 nucleolar protein
- RNA cytidine acetyltransferase
- WD repeat-containing protein 46
- Nucleolar protein 10
- WD repeat-containing protein 3
- Bystin
- WD repeat-containing protein 43
- BMS1 ribosome biogenesis factor
- Neuroguidin
Sequence:
MAELQPLALQLEQLLNPRPREADPEADPEEATRARVIDRFDEGEEEEDDLPVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWDQTLPSSSDNEIPDEGGSEAGDSEGLEELSEDVEEDLEDNEIPDEGGSEDGDSEGLEEEISEDVEEDLEGEDEEDREEDRNSEDDGVVMAFSGVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRYLVKGTKPNAESEEISSEDDELVGEKKKQRKAPPKRKLEMEDYPSFMAKRSADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHILMDKERLLRRTQTKRSAYRVLGKPEPVPEPVAETLPGEPESLPQVPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTAMNDEARTELYRSLFGQLNRLDADHGQ
Protein: Tyrosine-sulfated glycopeptide receptor 1 (EC 2.7.11.1) (PSY1 receptor) (Q9C7S5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Tyrosine-sulfated glycopeptide receptor with a serine/threonine-protein kinase activity. Regulates, in response to tyrosine-sulfated glycopeptide binding, a signaling cascade involved in cellular proliferation and plant growth. Not involved in PSK perception. Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances. Mediates activation of the plasma membrane H(+)-ATPase by PSY1. Phosphorylates AHA2 at Thr-881.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25267325}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- ATPase 2, plasma membrane-type
- Protein PSY1
- Protein-tyrosine sulfotransferase
- Transmembrane protein
- At3g62990
- ATPase 1, plasma membrane-type
- Cyclic nucleotide-gated ion channel 17
- Copper transport protein family
- Phytoene synthase 1, chloroplastic
- UPF0481 protein At3g47200
Sequence:
MIDEKMRSKSIGPFVRQVKPLSPHMVLFVLLYVLSISVFFLTVSEAVCNLQDRDSLLWFSGNVSSPVSPLHWNSSIDCCSWEGISCDKSPENRVTSIILSSRGLSGNLPSSVLDLQRLSRLDLSHNRLSGPLPPGFLSALDQLLVLDLSYNSFKGELPLQQSFGNGSNGIFPIQTVDLSSNLLEGEILSSSVFLQGAFNLTSFNVSNNSFTGSIPSFMCTASPQLTKLDFSYNDFSGDLSQELSRCSRLSVLRAGFNNLSGEIPKEIYNLPELEQLFLPVNRLSGKIDNGITRLTKLTLLELYSNHIEGEIPKDIGKLSKLSSLQLHVNNLMGSIPVSLANCTKLVKLNLRVNQLGGTLSAIDFSRFQSLSILDLGNNSFTGEFPSTVYSCKMMTAMRFAGNKLTGQISPQVLELESLSFFTFSDNKMTNLTGALSILQGCKKLSTLIMAKNFYDETVPSNKDFLRSDGFPSLQIFGIGACRLTGEIPAWLIKLQRVEVMDLSMNRFVGTIPGWLGTLPDLFYLDLSDNFLTGELPKELFQLRALMSQKAYDATERNYLELPVFVNPNNVTTNQQYNQLSSLPPTIYIKRNNLTGTIPVEVGQLKVLHILELLGNNFSGSIPDELSNLTNLERLDLSNNNLSGRIPWSLTGLHFLSYFNVANNTLSGPIPTGTQFDTFPKANFEGNPLLCGGVLLTSCDPTQHSTTKMGKGKVNRTLVLGLVLGLFFGVSLILVLLALLVLSKRRVNPGDSENAELEINSNGSYSEVPPGSDKDISLVLLFGNSRYEVKDLTIFELLKATDNFSQANIIGCGGFGLVYKATLDNGTKLAVKKLTGDYGMMEKEFKAEVEVLSRAKHENLVALQGYCVHDSARILIYSFMENGSLDYWLHENPEGPAQLDWPKRLNIMRGASSGLAYMHQICEPHIVHRDIKSSNILLDGNFKAYVADFGLSRLILPYRTHVTTELVGTLGYIPPEYGQAWVATLRGDVYSFGVVMLELLTGKRPMEVFRPKMSRELVAWVHTMKRDGKPEEVFDTLLRESGNEEAMLRVLDIACMCVNQNPMKRPNIQQVVDWLKNIEAEKNQNNREEPEEEEET
Protein: Ejaculatory bulb-specific protein 3 (Ejaculatory bulb-specific protein III) (PEB-meIII) (PEBmelIII) (Q9W1C9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Protein component of the posterior mating plug.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Ejaculatory bulb-specific protein 1
- Ejaculatory bulb-specific protein 2
- General odorant-binding protein 19d
Sequence:
MKMILALVVLGLVLVAAEDKYTTKYDNIDVDEILKSDRLFGNYFKCLVDNGKCTPEGRELKKSLPDALKTECSKCSEKQRQNTDKVIRYIIENKPEEWKQLQAKYDPDEIYIKRYRATAEASGIKV
Protein: KNL (Kinetochore null) Binding Protein (Q9N2X3)
Organism: Caenorhabditis elegans
Interaction partners:
- Kinetochore-binding protein 3
- Kinetochore protein Nuf2 homolog
- Kinetochore protein ndc-80
- Kinetochore NuLl
- Outer kinetochore KNL1 complex subunit knl-1
- Mitotic spindle assembly checkpoint protein MAD2A
- Spindly-like protein spdl-1
- BUB1 N-terminal domain-containing protein
- Centromere/kinetochore protein zw10 homolog
- MAD related
Sequence:
MQKSIDDMINEVLAVKVEKLPKTQDFSDLQEVCASKLQIINKEMDEADRKLEETLEKRKLVEKQLEDLQEQYKVKEFAFSLQKEFQDELKKVAEEIF
Protein: Large ribosomal subunit protein uL23m (54S ribosomal protein L41, mitochondrial) (YmL41) (P32387)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL41
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein uL24m
- Small ribosomal subunit protein uS12m
- Large ribosomal subunit protein uL4m
Sequence:
MPRLTVGTKNMLYPLQKTLAVGSCKPEQVPIRSLASVVESSSKILDKSGSDREVDINVSEKIYKWTKAGIEQGKEHFKVGGNKVYFPKARIILLRPNAKHTPYQAKFIVPKSFNKLDLRDYLYHIYGLRAMNITTQLLHGKFNRMNLQTTRFREPQIKKMTIEMEEPFIWPEEPRPDENSFWDSTTPDNMEKYREERLNCLGSDANKPGTAFDGVVGPYERVAQPFIPRFLKREIDNKRERHAAELQRADKLIALNRYIEDLH
Protein: Cellular tumor antigen p53 (F1SY23)
Organism: Bos taurus (Bovine)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm {ECO:0000256|RuleBase:RU003304}. Nucleus {ECO:0000256|RuleBase:RU003304}. Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}. Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}. Nucleus, PML body {ECO:0000256|ARBA:ARBA00004322}.
Interaction partners:
Sequence:
MEESQAELNVEPPLSQETFSDLWNLLPENNLLSSELSAPVDDLLPYTDVATWLDECPNEAPQMPEPSAPAAPPPATPAPATSWPLSSFVPSQKTYPGNYGFRLGFLQSGTAKSVTCTYSPSLNKLFCQLAKTCPVQLWVDSPPPPGTRVRAMAIYKKLEHMTEVVRRCPHHERSSDYSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYESPEIDSECTTIHYNFMCNSSCMGGMNRRPILTIITLEDSCGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGQSCPEPPPRSTKRALPTNTSSSPQPKKKPLDGEYFTLQIRGFKRYEMFRELNDALELKDALDGREPGESRAHSSHLKSKKRPSPSCHKKPMLKREGPDSD
Protein: Polyubiquitin [Cleaved into: Ubiquitin] (Q5ADS0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Large ribosomal subunit protein eL40
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-activating enzyme E1 1
- E2 ubiquitin-conjugating enzyme
- Ubiquitin carboxyl-terminal hydrolase
- Proteasome regulatory particle lid subunit
- HECT-type E3 ubiquitin transferase
- Ubiquitin-conjugating enzyme E2 1
- Proteasome regulatory particle base subunit
- Proteasome subunit beta
Sequence:
MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGF