wanglab/gogpt-training-data huggingface dataset:
Protein: Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) (O60941)
Organism: Homo sapiens (Human)
Function: Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity). May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:27223470}. Postsynaptic density {ECO:0000250|UniProtKB:P84060}. Cell projection, dendrite {ECO:0000250|UniProtKB:O70585}. Basal cell membrane {ECO:0000250|UniProtKB:O70585}. Postsynapse {ECO:0000250|UniProtKB:O70585}. Nucleus {ECO:0000269|PubMed:27223470}. Note=Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells. {ECO:0000250|UniProtKB:O70585}.
Interaction partners:
- Gamma-2-syntrophin
- Dystrophin
- Gamma-1-syntrophin
- Beta-2-syntrophin
- Dystroglycan 1
- Beta-1-syntrophin
- Dysbindin
- Alpha-1-syntrophin
- Utrophin
- Protein phosphatase 1 regulatory subunit 21
Sequence:
MIEESGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYVARLQHCARVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSAEEGAEEEEEKMQNGKDRG
Protein: H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (Dyskerin) (F1Q749)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:O60832}. Nucleus, Cajal body {ECO:0000250|UniProtKB:P40615}.
Interaction partners:
- Nucleolar protein 58
- H/ACA ribonucleoprotein complex subunit 3
- Protein SHQ1 homolog
- H/ACA ribonucleoprotein complex subunit 1
- Nucleolar protein 56
- H/ACA ribonucleoprotein complex subunit 2-like protein
- rRNA 2'-O-methyltransferase fibrillarin
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- WD repeat-containing, antisense to TP53.
- Telomerase reverse transcriptase
Sequence:
MADTESKKEKKRKSKKISDEEVGDIQESGDFLIKPESKVASLDTSQWPLLLKNFDKLNIRTAHYTPLPHGSNPLKRGIHDYVRSGFINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCVERATRLVKSQQSAGKEYVGIVRLHNALENEHQLARALECLTGALFQRPPLIAAVKRQLRVRTIYESKLIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVLGEKDNLVTMHDVLDAQWQFDHNKDETYLRRVIFPLEKLLISHKRIVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQDIVVITTKGEAICTAVALMTTAVISTCDHGVVAKIKRVIMERDTYPRKWGLGPKASQKKMMIQKGLLDKHGKPNNSTPSDWKEGYVDYSTTKVKKGGEASAKRKRDESGSEGEAAAAAQDTSKTEEESKKEKKKKKKEKKQKLAEEAAAEAPAEEETEVTESAKKKKKKKKAKETEADSD
Protein: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Endopeptidase Clp) (P63786)
Organism: Staphylococcus aureus (strain MW2)
Function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00444}.
Interaction partners:
Sequence:
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
Protein: Smad nuclear-interacting protein (Q4V8W8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- RNA-binding motif protein, X-linked 2
- Activating signal cointegrator 1 complex subunit 3
- SNW domain-containing protein 1
- BUD13 homolog
- Splicing factor 3B subunit 1
- MCG1346-like protein
- Pre-mRNA-splicing factor CWC22 homolog
- Splicing factor 3a, subunit 3.
- E3 ubiquitin-protein ligase RNF113A
- Splicing factor 3B subunit 2
Sequence:
MDNRRRHRDSPVRDVKTKIKQERLSPARPPRARRHSSGSSRDSSSPAQRRRDSRSPVRRKDRSPARRDRSSGRQQERSPRPRRSRSPHRNTEARIKREQDDPRGSESHRHRERRDDSNDRRLKREAERPRQRDRGREQDRQRGRIRDAHIQEQQQAERERHNERRRENRLRQEAQSGGAEEMLEFGGENNDESAPAAEKEKPNFELSGALVEDTNTFRGEVIKYNEPPEARIPKRRWRLYPFKNDEPLPVMYIHRQSAYLLGRLRKIADIPIDHPSCSKQHAVFQYRLVEFTRVDGTAGRRVKPYIIDLGSGNGTYLNNQRIEPQRYYELKEKDVLKFGFSSREYVLLHEFSDTTEVDAKKKEEEEEEDEGLDE
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (Q7KSQ2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNSHATATQNGQTTVVGHHRGFSQPSVTVAAAAATGSTAGDPWFLQTTGHQMPPTAPLRHNKRPAPQPNAVLGAGSSGTAPGSAVGAVLLHQQQLSQSQPHIVPPSIPPHHHHHRENNVHPIQAGAAAALHLSSHALNSHNLISSASNHSPKSPSQTQQQQQTTNQQQQQQQQQASHSILSTFAPAPTVAAVQPAGSQSVAGTAAAVAAVAQQQQQQHLQLLANCPPGGAGLMSSSLNAAQMGMHGAERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGVNASSAWSSGSTTAMNHASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLKDEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECYNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLLNNATA
Protein: HOX2.8 protein (Q14548)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
APRCPPGPRVPLDEREEIRQETQPIRHVSFSGRLRRSGSGVGSPADGLGLRRLVAAGPQAAHGLHQHAAAGTGEGFTFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAEEPAPARAAPALAGGVGSLLSPAGGGAGGLKRGPPAFSRSLRA
Protein: Metalloprotease TldD (EC 3.4.-.-) (P0AGG8)
Organism: Escherichia coli (strain K12)
Function: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).
Interaction partners:
- Metalloprotease PmbA
Sequence:
MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA
Protein: SPARC-related modular calcium-binding protein 2 (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2) (Q9H3U7)
Organism: Homo sapiens (Human)
Function: Promotes matrix assembly and cell adhesiveness (By similarity). Can stimulate endothelial cell proliferation, migration, as well as angiogenesis.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}.
Interaction partners:
Sequence:
MLLPQLCWLPLLAGLLPPVPAQKFSALTFLRVDQDKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSVNEKLPQREGTGKTDDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKGRQLQGCPGAKKHEFLTSVLDALSTDMVHAASDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELMGCLGVAKEDGKADTKKRHTPRGHAESTSNRQPRKQG
Protein: Nucleolar GTP-binding protein 2 (Autoantigen NGP-1) (Q13823)
Organism: Homo sapiens (Human)
Function: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:21495629}.
Interaction partners:
- Ribosome production factor 2 homolog
- GTP-binding protein 4
- Probable ribosome biogenesis protein RLP24
- Ribosome biogenesis protein NSA2 homolog
- Guanine nucleotide-binding protein-like 3-like protein
- Guanine nucleotide-binding protein-like 3
- Zinc finger protein 593
- Ribosome biogenesis protein NOP53
- mRNA turnover protein 4 homolog
- Pescadillo homolog
Sequence:
MVKPKYKGRSTINPSKASTNPDRVQGAGGQNMRDRATIRRLNMYRQKERRNSRGKIIKPLQYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVMKDPYKVVMKQSKLPMSLLHDRIRPHNLKVHILDTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ
Protein: DNA N-6-adenine-methyltransferase (DAM) (EC 2.1.1.72) (EcoP1I DNA MTase) (M.EcoP1I) (Type II methyltransferase M.EphP1ORF2P) (M.EphP1ORF2P) (Q71TL0)
Organism: Escherichia phage P1 (Bacteriophage P1)
Function: Methyltransferase that methylates adenine residues in the ssDNA and dsDNA sequence 5'-AGACC-3'. Essential for genome packaging because methylation within the pac site makes the latter cleavable. May prevent degradation of viral DNA by the host restriction-modification antiviral defense system (Probable).
Interaction partners:
Sequence:
MKELCYGSVCSGIEAASIAWEPLGMRPAWFAEIEPFPSAVLAHRWPHVANLGDMTKLAKKVLAGEIESPDVLVWGTPCQAFSIAGLRGGLDDERGALTLKYVELANAIDDKRSESFLKPTVIVWENVPGVLSSADNAFGCFLAGLAGEDAPFEPGDRPESGKSNAFWRWDGKTGCHAPKWPQCGCIYGPQRKVAWRILDAQYFGVAQRRRRVFVVASARTDLDPATVLFEFEGVRRNIAPRRKKKEIASAIIANGAAISGESLNPCLHADMPPSMKSTKAVNAFRMAAFGEYIDDETASTVKARDFKDATDLAVFSSTGAGFWSEGHGTLRAREQESHEHLVTLAFPERMSGTQHAATKNTSPSLMAKNPTAVCYEVRNAEVAVRRLTPVECERLQGFPDGHTLIPTEKRKKVNSDELAYLRNHYPDLSEEEAAMLAADGPRYKAIGNSMAIPVMRWIGDRITKAVCRQKEGSETKERKVKPAAEFERSIFKWAGGKFGVLEQIFRYLPEGKRLIEPFVGGGAVFTNAGYQENLLNDVNADLINFYKTLQREAHSLITLAHRFFQDYNTQEGYLAVRNAFNKQVYDDLHRAAAFLFLNRHCFNGLTRYNQAGEFNVGYGKYKTPYFPLQEMEAFLGAEGRSEFVCGDFAAVIEAAGEGDVIFCDPPYEPLPNTEGFTNYSGHDFKFEEQKRLVSLLTDAHRRGAKVLITNSGAPNIRELYHDSGFRVEPLFARRSVSCKGDTRGVAHDVLGILL
Protein: mRNA transport regulator MTR2 (P34232)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Affects mRNA transport from the nucleus to the cytoplasm.
Subcellular location: Nucleus.
Interaction partners:
- mRNA export factor MEX67
- Nuclear cap-binding protein subunit 2
- Probable metalloprotease ARX1
- Nucleoporin NUP116/NSP116
- RNA annealing protein YRA1
- Nuclear mRNA export protein SAC3
- Nucleoporin NUP84
- Nucleoporin NUP159
- 60S ribosomal export protein NMD3
- Nucleoporin NUP85
Sequence:
MNTNSNTMVMNDANQAQITATFTKKILAHLDDPDSNKLAQFVQLFNPNNCRIIFNATPFAQATVFLQMWQNQVVQTQHALTGVDYHAIPGSGTLICNVNCKVRFDESGRDKMGQDATVPIQPNNTGNRNRPNDMNKPRPLWGPYFGISLQLIIDDRIFRNDFNGVISGFNYNMVYKPEDSLLKI
Protein: C-C motif chemokine 1 (Small-inducible cytokine A1) (T lymphocyte-secreted protein I-309) (P22362)
Organism: Homo sapiens (Human)
Function: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.
Subcellular location: Secreted.
Interaction partners:
- C-C chemokine receptor type 8
- C-X-C motif chemokine 11
- C-C chemokine receptor type 5
- C-C chemokine receptor type 1
- Atypical chemokine receptor 4
- CDK-activating kinase assembly factor MAT1
- C-C motif chemokine 5
- C-C chemokine receptor type 6
- C-C chemokine receptor type 2
- C-C chemokine receptor type 3
Sequence:
MQIITTALVCLLLAGMWPEDVDSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK
Protein: RNA helicase (EC 3.6.4.13) (A0A060Y3B2)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- RLR CTR domain-containing protein
- Fanconi anemia group G protein
- RNA helicase
- E3 ubiquitin-protein ligase FANCL
- FA complementation group F
- FA complementation group B
- RecQ mediated genome instability 2
- Toprim domain-containing protein
- Toprim domain-containing protein
- RecQ-mediated genome instability protein 1
Sequence:
MADFGLYEYQEEVVQRALRGENIIIWLPTGGGKTRAAVYVAKKHLENNPGAKVAVLVNKVHLVDQHYNNEFNPYLGSDYSLVSISGDCDQKDFFGCEVKNSDLVICTAQILENALTNQEEGKHVELSQFTLLIIDECHHTHKEGVYNKIMARYVAQKLKGERRLPQILGLTASPGTGGAKSIKGAVEHVLQICANLDSVIVSSKVYAPELKKKVPRPRKRFDIVDRRPQDPFGDHLKFMMQFIHDFMALGPEFPVREFGTQEYEADVVILEKKGVTDRNRLLAQCALHLRQYNDALLINDTVRMVDAFRVLESYYSTKSSTAMDGTDFFLLGLYQENEVELRKLSGDARFENPKMGKLQNTLLEQFVQGGHSRGILFSKTRKSICCLYDWVSNNPALQRAGIRAAILTGAGNGINYMTQNEQKDTIRNFRLGSLNLLISTSVAEEGLDIPECNLVVRYGLLTNEIAQQQASGRARASDSVYSVVAQAGGREVRRELLNECLEDLTGRAIGEVQRMEPRDFQMKITDLQTEALLTRQLAEQLKLKKRSRFNAATVQLSCRGCFLPVALGHDIKVIENAHHVNINPDFERYYKTGGQPALKTFEDWEPGRVISCAACGRQWGMEMIYKNIALLPILAIENFAMETPEGRKLAKKWKNVEFTVEEFNFSTYCHNKFPNMLD
Protein: BHLH-like protein (Q69MD0)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MVAARSGDDAELRLDVECLAAAPRWTRARRSHSEAERKRRERINAHLDTLRGLVPSASRMDKAALLGEVVRYVRKLRSEAAGSAAVVPGEGDEVVVEEEEVEVEGCSCDAGERQAARRVKASVCCADRPGLMSELGDAERSVSARAVRAEIATVGGRTRSDLELDVARTAAAGGGSNGASQLPALQAALRAVIMSQEELLAVESYKQRRFSADFA
Protein: ERI-6/7 (B5TRE1)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTDKENFYSGFFLGRLPGSFDSRFLIKVACFQPGKEERNVFELTTDTKREEDYGEMVHFWVDKGPLQNKSFVRFEENYETFFIHENKMFDRIVHTDKDFYVGVNDLPDSDIYIHPDLGKMIDTRSIVTPGKKYNFITFEVKQNENNSFDIEIVGGEVQGKEKNSEEPSAKEKIIQKMEQVHEVMKVEYEYNKNEETANWDVIGHLKLIKFYDKDLTSGLRPVLRLMDNRHVALFKKQRETMPIKMIKVIEVDGIWKDDVNFVPQEGTLLPTDHDEKTVVLLGNDYRHKFERLFKREDVFRLESNNTLTHLKFWQNQKQNTNPVYQYTLEDNPESLTLQDVLESHMTDPIELNSFDSMEKEAGIPFSNEKQRTAIKMALNENRKLVCIQGPPGTGKTFTLTLLLCRLIQQKKQVVVLAPTREALANIRMMTKKTLKRMGIKVHEHALMDTNEYRDVINKSDRALMAAEEVRDLRKAFDNGEITENVLDEMRQSIINRVRNEVGAEVIGNVRVAFATIGASFVDFVMKHKKFDPCLCIIDEAAQVMEAQTWPAVYKMKRIVMAGDPKQLPALVFTDEAKAFGLQNSVMDRILEKKNNFSWIMLENQYRSNAKIATWSNTCFYHNQLKTDVKCHEYSLHTILNPQPKKFRNLFDPLVLIDTSLERDVEKRLETYEHAVFDTNSINKTKQGFSYANLAEAKIAIGHYQRLLKYGVQPSDIAIITPYKGQTSLVTKLMEEFGAETGYTDFVQTTIGTVDSVQGKEYEVVIFTMVRSNPRKTMGFVSELRRLNVVITRAKRHFMFIGNGYLLAESKKDEIRKLYDCFKNAKRRFHPNNAFGEDGNVTDYVSNNFGQDLESFMNYSNDEEMINWCKRFNENGPDYRAKKALAWEKREETRLMKTISKVKYEYKRGSTEQLASELDQLDCSSN
Protein: Formin homology 2 domain containing, isoform H (M9ND66)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPSYRLRHIDSGEEQAWWLRQDENGDDDDTLAEETLNTLDDDLQEPSKSTWWSQDDQDSSSQVKLMPRSRITPEKDAWWLQDEDEAAKSPIENGDLNNNNNSEPHVEVTLRLPSNGSQRSSKSSASKNGSNPKSGGANPWWLSGPARKMFNVQRVESGERAWWQEEAEEPPQEEKESEPPPVKPPTPPPRIIKHWESGERAWWLQDETESNQLPVQASSDDEEQPVLVVINQQESRDEVDLRLAPPTLESQELSNSFNFDAHSERPPPLGQCASPVRCPSPYDNIPRSQLQEPPPPPTTTLTSLQPRFSPQTRRAGEKLFISRHQNIDELLGGACRPLSPLFYGNSNPAESELTPLAGKNMFLLEEVTPDQVRIHDSTAQLPVIQRMQRDVEWLDNGSNFYEPPEQRQHQPPRRIDDAAIQVYKDGDYGAYLDLESSLAEQAEEIEGVNVSRKNSLVVRTQLNVRVQAIIEKLLSAQGSDLRRALFSLKQVFQEDKDLVHAFVALGGLNCLVRVGNCADQNYQNYILRALGQVMLYVDGMNGVMKHEPTMQWLYSLIASNYRSVVKTALKLLLVFVEYAESNCYVLVSAIHAVDASQGTLPWSNIMRLLKDYDNADAELVIYATSLINKTLAGLNDQDSFYDESDLLEQQGMETVIQRYMSKPGTDLDLLDQLQLYEAVLKFEDGESDGQRLPQNSMRKTQRYRPGANTTERRKSRRHSTDNSPASLTKVLPTTVLRMTPTQATVDEDSSGSTNSTEFSGGLFNEKKPRDGAGVTPGLRRRRERAERHKSFLKEQQEAAANGIFAALEQREGLGQIVTAIPATIQTGDSPPQSLQHEVPPCNNISGITNISNNNVSNLSCNDTPNNSLLVMSPSKQLLTGSHSISIINNSFDKASNNNQSEFLTKKNLFRERNSTVINGIMKNIQQTDSAYKKYENEANRLNNYYSQSPKHQIHQPIQPTPEVLLSPKKTLNASGFDFTPAPLSSTPVKCDVPPEPEPLSPVKKPAAAPPPPPPPPPPPPPPPGWWHAPIYNSPQARTLTSTNPELLPHPVDPSDMESEDQQLLLQLKRDHTVKDLTQKLSNLPMSPTQDSANRALVGDMSGLISKAKEGLAKSKSKGEISRSSSVDQDVKKSEPKKSENELHWEELVRNMTRPLNLCDLDFTDLRDDDEKDVLAPRSLGAGIPPPPPPLGGAIAPPPMMPPSLAPPPMYGYGGSLTNSVNSLNGSINGELVNGNNTIKKNKKTVKLFWKEVREDMIPQVVGKTIWDELPDANVDTQKLEHLFESRAKDLMTKKQQELNKSKEIIVLDHKRSNAINIAITKLPPPRAIKTAILKMDATVVTREGIDKLLNMLPTDEERGKIQEAQLSNPELPLGSAEQFLLTLASISELEARLKLWAFRLDFDNSEKEIAEPLMDLKQGIEILRQNRTFRSILSTLLSVGIFLNGAPVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMESSSDTSDLYSEIGPITRASKADFTDLAHNLNQLEAECKACWDRLKLIAKHDCPPPLKQKLVDFLADCAERIIILQIVHRRVMNRYRKFLLWLGMPQHSVAESRPNEFCRTLSEFALEYRTTRERVQQQLEKKANHRERNKTRGKLIIDMAKFKTKDDVADDELKKLLDTSSADQADGTLTWRRRRAEQLRSPITRQSEEQFTDGDDEILESLVKTATKAPGTRTTPRERKRTRHADRKSLRRTLKNGLTEEEKQHVAALIQTY
Protein: Pyruvate dehydrogenase E1 component subunit alpha-1, mitochondrial (PDHE1-A) (EC 1.2.4.1) (P52901)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:14671022}.
Interaction partners:
- Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta-2, chloroplastic
- Pyruvate dehydrogenase E1 component subunit beta-3, chloroplastic
- Dihydrolipoyl dehydrogenase 1, mitochondrial
- Dihydrolipoyl dehydrogenase 1, chloroplastic
- Dihydrolipoyl dehydrogenase 2, chloroplastic
- Dihydrolipoyl dehydrogenase 2, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component 5 of pyruvate dehydrogenase complex, chloroplastic
- Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component 4 of pyruvate dehydrogenase complex, chloroplastic
Sequence:
MALSRLSSRSNIITRPFSAAFSRLISTDTTPITIETSLPFTAHLCDPPSRSVESSSQELLDFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLGRGGSLHEVFSELMGRQAGCSKGKGGSMHFYKKESSFYGGHGIVGAQVPLGCGIAFAQKYNKEEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKQHALEKGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGPDRKEVKASLP
Protein: Xin actin-binding repeat-containing protein 1 (Cardiomyopathy-associated protein 1) (O70373)
Organism: Mus musculus (Mouse)
Function: Protects actin filaments from depolymerization.
Subcellular location: Cell junction, adherens junction {ECO:0000250|UniProtKB:Q5PZ43}. Cell junction, desmosome {ECO:0000250|UniProtKB:Q5PZ43}. Cell junction {ECO:0000269|PubMed:23985323}. Note=Colocalizes with actin stress fibers. {ECO:0000250|UniProtKB:Q702N8}.
Interaction partners:
- Nebulin-related-anchoring protein
- Cysteine and glycine-rich protein 3
- Titin
- Myozenin-2
- Filamin-C
Sequence:
MADAQMQVAPTPTIQMRTEEDLSLPHPSAPEGLPPPPPKETFSKFQQQRQASELRRLYKHIHPELRKNLEEAVAEDLAEVLGSEEPTEGDVQCMRWIFENWRLDAIGDHERPAAREPVSGGNVQATSRKFEEGSFTNSSDQEPEGLRPSGGDVQAARQMFETKPLDALRGQEEATQTTMREPAATGDVQGTRKLFETRPLDRLGSRPSIQEQSPLELRSEIQELKGDVKKTVKLFQTEPLCAIQDAEGTIHEVKAACREEIQSNAVRSARWLFETRPLDAFNQDPSQVRVIRGISLEEGALPDVSATRWIFETQPLDAIREIEVDEKDFQPSPDLIPPGPDVQHQRHLFETCSLDTLKGERETEAEVPPKEEVIPGDVRSTLWLFETKPLDAFRDQVQVGHLQRVGHQEGEGLVTECLPSNGTSVLPLSQGVPQNDGLKGDVKTFKNLFETLPLDSIGQGEPSAYGNINRGQNTDSAEQSQGSDAPVYAMQDSRGQLHALTSVSREQVVGGDVQGYKWMFETQPLDTLGRSPSTIDVVRGITRQEVVAGDVGTTRWLFETQPLEMIHQQEQQKPEEEEGKGPGGPPPELPKKGDVQTIRWLFETYPMSELAEKRESEVTDPVSKAETQSCTWMFGPQSLNPAEGSGEQHLQTSQVPAGDRQTDRHVFETESLPASNQSSGRKPVRYCSRVEIPSGQVSRQKEVFQALEAGKKEVPETTINLGSIPTGSVHKFTWLFENCPMGSLAAESIRGDNLQEEQPKGSAGHGTPERQETAAERTLRTLHATPGILHHGGILMEARGPGELCLAKYVLPSPGQGRPYIRKEELVCGELPRIVRQVLRRTDVDQQGLLVQEDTAGQLQLHPLMLPGPGDPGNIEDMDPELQQLLACGLGVSVSKTGLVMQETGQGLVALTAYSLQPQLTSRAPERSSVQLLASCIDKGDLHSLHSLRWEPPTDPSSGPATEESQRVPPTESIIHVTPLDSTMEMGQLRISGSTPCPPPSRAAGKVVLPNGKPVAQAPLQEARKKRDISHAGQKGKAASGRPEASPLGSGAPDLQEAMQNLRLATAEAQSLHQQVLSRHPQGSDPVATSMPVQDVLQASTPATGVTQGSIRPVAGSEARIPAVPRKLL
Protein: Serine protease 33 (EC 3.4.21.-) (Tryptase-6) (mT6) (Q80WM7)
Organism: Mus musculus (Mouse)
Function: Serine protease that has amidolytic activity, cleaving its substrates before Arg residues.
Subcellular location: Secreted {ECO:0000269|PubMed:14583634}.
Interaction partners:
Sequence:
MRGASHLQILLLLVLGTRMQECAACGQPRMSSRIVGGRDAQDGEWPWQTSIQHRGAHVCGGSLIAPQWVLTAGHCFPRRVWPSEYSVLLGALSLDVRSSHELLVPVLRVLLPPDYSEDEARGDLALLQLRHPVSLSTRIQPVCLPAPGSHPPPGSPCWVTGWGSLSPGVPLPKGRPLQGVRVPLLDSRACDRLYHVGANVPQGERIVLPGNLCAGYRRGHKDACQGDSGGPLTCMESGHWVLVGVVSWGKGCALPNRPGVYTNVAKYSPWIQARLSL
Protein: Stabilizer of axonemal microtubules 4 (Protein IIIG9) (Protein phosphatase 1 regulatory subunit 32) (Q66HR9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:28194645}. Cytoplasm {ECO:0000269|PubMed:28194645}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q148A4}. Note=Localized to the cilia of polarized ependymal cells during development and at the adult stage. Preferentially locates between the peripheral microtubules of the axoneme and the ciliary membrane. {ECO:0000269|PubMed:28194645}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
Sequence:
MMGKLPLGVVSPYVKMSSGGCSDPLKFYATSYCTAYGREEFKPRMGSHVGTGYKSNYRPLVSYQPHLDTLDNPAVGEQIHDTSKSVASQSYAPLEVPDGKQPLPWNLHQTTSGYGREKVNIGPLSKEVRKVHFDTQDHGPQTITGLEPKEVPLIHQQQGKGSTEWENSRYGPRFMTSEYNSKYLKESPNHPDLLLKKTIGSKEETGFTEESTKNPIVFQPPSQAYPGDPVLHPGRSITKSDYLPISHPQGNEFLPVLARGSDRDTGYSRVSERSLNPRMPTPSSQPTSMSHRSYQPPQRMQQSNVALLGRESVGNKEPTGFTLNNPSYVRSSYEQDRDQRYLTTYNQGYFENIPKGLDREGWTRGGIQPQKAGAYALSEPVTHMDTTPNPTETLRHLHPHVGRTLTSVDPFYRDVPHSNRYPTSS
Protein: At2g01340 (Plastid movement impaired protein) (Q52K81)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At3g61920
- At1g64700
- 6,7-dimethyl-8-ribityllumazine synthase
- Basic-leucine zipper transcription factor K
- At3g03280
- At3g10120
- Emb|CAB85509.1
- 6,7-dimethyl-8-ribityllumazine synthase
- Uncharacterized protein At5g17350
- DUF4228 domain protein
Sequence:
MGNSLGGKKTTKVMKIDGETFKLKTPVTAEEVLKDFPGHVLLDSESVKHYGARAKPLEAKQRLEAKRLYFVVEPVKECPPRRVRSGIHVSAKERLESLMLARRSSSDLSILKPPGGWTTEEEEGAVRRVKVRIPKAELEKLVKEGATEAEATQKIAALFMAKQRQEEAYQNTRQDEPATTATATATTTATRGVKSRLKRVSFMAERGGGSEITVA
Protein: Urease accessory protein UreE (Q09064)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.
Subcellular location: Cytoplasm.
Interaction partners:
- Urease accessory protein UreH
- Urease accessory protein UreG
- Urease accessory protein UreF
- Urease subunit beta
- Acid-activated urea channel
- Urease subunit alpha
- Hydrogenase/urease maturation factor HypB
- Phosphoglucosamine mutase
- Lipoprotein signal peptidase
- Hydrogenase/urease maturation factor HypA
Sequence:
MIIERLVGNLRDLNPLDFSVDHVDLEWFETRKKIARFKTRQGKDIAIRLKDAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGNRHAALYYGESQFEFKTPFEKPTLALLEKLGVQNRVLSSKLDSKERLTVSMPHSEPNFKVSLASDFKVVVK