wanglab/gogpt-training-data huggingface dataset:
Protein: Superoxide oxidase CybB (SOO) (EC 1.10.3.17) (Cytochrome b-561) (Cytochrome b561) (Superoxide:quinone oxidoreductase) (Superoxide:ubiquinone oxidoreductase) (P0ABE5)
Organism: Escherichia coli (strain K12)
Function: B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:29915379, ECO:0000269|PubMed:3510204, ECO:0000269|PubMed:6097799}; Multi-pass membrane protein {ECO:0000269|PubMed:29915379}.
Interaction partners:
- Uncharacterized protein YdcA
Sequence:
MENKYSRLQISIHWLVFLLVIAAYCAMEFRGFFPRSDRPLINMIHVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGLVMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHYFWKDNTLLRMMPRKRS
Protein: Regulator of G-protein signaling 11 (RGS11) (O94810)
Organism: Homo sapiens (Human)
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
Interaction partners:
- Guanine nucleotide-binding protein subunit beta-5
- Regulator of G-protein signaling 7-binding protein
- Regulator of G-protein signaling 9-binding protein
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- Glutathione hydrolase 5 proenzyme
- Guanine nucleotide-binding protein subunit alpha-13
- Guanine nucleotide-binding protein G
- Rho guanine nucleotide exchange factor 1
- Beta-adrenergic receptor kinase 1
- Rho guanine nucleotide exchange factor 11
Sequence:
MAAGPAPPPGRPRAQMPHLRKMERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGSDVVQWLAQKFCVSEEEALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTSTLRPAAELDYAIYLAKKNIRKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAKQRSKGDRLVIACQEQTYWLVNRPPPGAPDVLEQGPGRGSCAASRVLMTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDAQLHIYMLMKKDSYPRFLKSDMYKALLAEAGIPLEMKRRVFPFTWRPRHSSPSPALLPTPVEPTAACGPGGGDGVA
Protein: Phosphatidylinositol binding clathrin assembly protein (H0YD48)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
Protein: pH-response regulator protein palF/RIM8 (P78612)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.
Interaction partners:
- pH-response regulator protein palH/RIM21
- pH-response transcription factor pacC/RIM101
- Calpain-like protease palB
- Vacuolar-sorting protein snf7
- pH-response regulator protein palC
- Vacuolar protein-sorting protein bro1
- Vacuolar protein sorting-associated protein 27
- pH-response regulator protein palA/RIM20
Sequence:
MVRATCSCVMSVNPLSAQTSASPLSRNRSSLLSKFRTQLGQRNRAITDFYIEPDDPWRSYFPGDVIKGTVSLTVVRPVRITHLVISLHGIVKVFKNNVPAGETPPDVGSLGPGRGRRGAEYLGNGVATLFEDEVVLCGEGRLKEGIYKFRFEMSFPPYPLPSSISFERGTISYMLTSTLTKPTTMNPTLSCRRRINLLENIDIAAFPAPKPRVVTLEPISKRSKPKGKTKAAGFDAPDTASLEPSASGGITVPEHRPPLSPAPSNVSSSSRLSNSSQSFQIVTDPGSTASSGVRNSEARSNTPSVTDGIITAKAEVLRAGVLPGDTLPIKITINHTKQVRSAHGIIITLYRSGRIDLHPAIPMGSTANGKKPIYEDYYPRSRTGLGGLTLGTSRASSVFRKDLSQTFAPLIVDPTTLTADIKTSIRIPEDAFPTITRTPGSMINFRYYVEVVVDLRGKLTSPERFLPRFNLVSSGRNFSSNGKIVHPADTNGSAITANWGDNILDTDQIRREKGVVAVIFEVVIGTQDTQRRKSEARRMSSTAEEAEFQQPVENSVDGDYAGHDYQGSMAGPEPGYAPLENTAYGPDQIRWPDYPEQSEHEHYPFQPGTLPSPQPDEPMDEKARLRRAEQTLLPSQPPCDPEAGPSSAVEAAMPTAPVLPEDDHLNDYHHLPSTTVNGMTGMAPALMSAESVQTVIAGSSSAPLTSPSRPSEEDKQELERQRLMMEASAPGDPDARHNDRADDGPSAPIFHDDDDDQQLVGGAANGDELLPRYQR
Protein: Peroxidase 52 (Atperox P52) (EC 1.11.1.7) (ATP49) (Q9FLC0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000255|PROSITE-ProRule:PRU00297}.
Interaction partners:
- Serine carboxypeptidase-like 20
- Cinnamyl alcohol dehydrogenase 8
- Flavone 3'-O-methyltransferase 1
Sequence:
MASNKLISILVLVVTLLLQGDNNYVVEAQLTTNFYSTSCPNLLSTVQTAVKSAVNSEARMGASILRLFFHDCFVNGCDGSILLDDTSSFTGEQNAAPNRNSARGFNVIDNIKSAVEKACPGVVSCADILAIAARDSVVALGGPNWNVKVGRRDARTASQAAANSNIPAPTSSLSQLISSFSAVGLSTRDMVALSGAHTIGQSRCTNFRARIYNETNINAAFATTRQRTCPRASGSGDGNLAPLDVTTAASFDNNYFKNLMTQRGLLHSDQVLFNGGSTDSIVRGYSNNPSSFNSDFTAAMIKMGDISPLTGSSGEIRKVCGRTN
Protein: Brevican core protein (A4JYN2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MFLHILLSAICLCVLSSSSVLSSATDDSSALKVAIPASSPVSAVLGGSLTLPCLVSLPRTPSLGRHAVLTQPRVKWSFLSSDRETEILVARGERVKVSEAYKGRASLLNYATSSADLTLRLEGLIHNDTGFYRCEVQHGLEDSHDQAQVKVKGVVFLYRHTSSRYAFTFDEARDACKDIGAEIASPEQLLAAYHSGYEQCDAGWLSDRSVRYPIQMPREGCFGDMDGLPGVRNYGTMENDELYDVYCYVENIHGEVFHGSTPQRFSLSEAKAYCEQQDAQLATTGQLYAAWNDGLNHCSPGWLADGSVRYPIVTPRERCGGSEPGVKTVYRFSNQTGFPEPNTRHDAYCFKANSNSQTAPPADYMATSPEETEQHIVTLAEPQEEYSVHQVTQRSENEAQGAVESFSIYSTQTASETEEHNHTSSPQEDIIIGSRKDLTTPTSTEGNTETIEVTWQNVGSIPEIYIDPKRNNFMLEGEPEIKASAVDGVKSSNHRHYQPMPDTNLEPGEPIDFIPPTVAHHGTTEEPSSPPKEINGSKHYQPMPDTNLDDEDHMTTQSTTLQYDSSNNTTQDASVQSTYHPDGATLETNAGNITEAPESDDNQGLFTHTTQPTSTSTSSREGWLESSGEDSTTEKAIYLDLTTKEAVNLDSTTEEPIHLDSTTEEAIHLDSTTEEAIHLDSTTEEAIHLDSTTEEAMFSTHNSEIYRASTAETLTESYSSTHLNNISPTDDVTDHFTLSTTLRETELSESSGDHDEVLPVILFTTPMPHLLDSLTTRAPVQLEISSPQQIEGVLSDSTTASALRVVEEEVEKVEQEELGEQPETKITTSTELNHSTVTLSIDGSDEEESSGEPSENWTSVTENPYSNTATITPSNLTDLQEHNETNSDDEDNQAITVEPTTDLEVTFLPHGTQTSIWQSVVTSPGELNADVEFSGEAALTTDDMRALEESESTNAPISEQTEETLKPSSTTDHNDADDDDNDNDDDELITKAITGNEEDENDVKTTHESFIIPVRPTQRVLIRTSYISDACLENPCKNGGTCVDSGGDQRCLCLPTYGGDFCETDLEHCEPGWEKFQGFCYKHFAKRQKWEVAEQHCRMCGGHLVSVMSPEEQLFINDKYREYQWTGLNDKTIEGDFRWSDGNPLLYQNWYRGQPDSYFLSGEDCVVMVWYDDGRWSDIPCNYQLSYTCKKGISAFCGQPPLVLHAKMFGRRQLKYRANSQVRYYCESGFIQRQNPIITCQSNGLWEEPKIMCSPAGPTYSNGDLVTWRTGQNKEIVIEDSTTKTPEYLDIKWNF
Protein: Solute carrier family 25 member 48 (Q6ZT89)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQTQPFRDANLGLKSRAVAPAEQPAYQGPVHCITTIVRNEGLAGLYRGASAMLLRDVPGYCLYFIPYVFLSEWITPEACTGPSPCAVWLAGGMAGAISWGTATPMDVVKSRLQADGVYLNKYKGVLDCISQSYQKEGLKVFFRGITVNAVRGFPMSAAMFLGYELSLQAIRGDHAVTSP
Protein: Putative uncharacterized protein YOR300W (Q08756)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Bud site selection protein 7
Sequence:
MKSRQDIQKLFSTWCRRICSISSLLAPLDATMHKYDKKTLIRIYNPKKIGDTLQRCVKLLGHFKENPAYINTEQCWLCNFAARRHSRKNIRVSRMRAKRKYQ
Protein: ribulose-phosphate 3-epimerase (EC 5.1.3.1) (Q3MIF0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Ribose-5-phosphate isomerase
- Transketolase
- transketolase
- transketolase
- Xylulose kinase
- Transaldolase
- RNA-binding protein 45
- 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
- GDH/6PGL endoplasmic bifunctional protein
- Probable gluconokinase
Sequence:
MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQKRSLDR
Protein: Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1) (d-mtTFB1) (Q9VTM5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. In contrast to mtTFB2, it does not have a critical role in either transcription or regulation of the copy number of mitochondrial DNA.
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- DNA-directed RNA polymerase
- LD31543p
- Bystin
- Pre-rRNA-processing protein TSR1 homolog
- LD10780p
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS13
- FI08810p
- Cytochrome c oxidase assembly factor 3, mitochondrial
- GH01043p
Sequence:
MAQPSARVLQSGMRLPPMPTIRELVKLYRLQARKQLSQNFLMDERLTDKIVKSAGRIDPRDLVLEVGPGPGGITRSILRRHPQRLLLVEKDPRFGETLQLLKECASPLNIQFDIHYDDILRFNIEQHIPDTSQRIHLIGNLPFAISTRLLINWLDDLAARRGAFRRIDTCMTLTFQQEVAERICAPVGGEQRCRLSVMSQVWTEPVMKFTIPGKAFVPKPQVDVGVVKLIPLKRPKTQLPFHLVERVVRHIFSMRQKYCRRGYGTLLPPEDREEVAEKLFQRAEVQDTLRPFELTVEQCLRLAEVYSEHLVTRPEVAAYDYRAPKNVEVL
Protein: Cupin family protein (Legumin-like protein) (RmlC-like cupins superfamily protein) (Q9SIA7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DNA repair protein XRCC3 homolog
- Meiotic recombination protein DMC1 homolog
- DNA repair protein RAD51 homolog 3
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A
- DNA repair protein XRCC2 homolog
- Proteasome subunit beta type-4
Sequence:
MELDLSPRLPKKVYGGDGGSYFAWCPEELPMLRDGNIGASKLALEKYGLALPRYSDSPKVAYVLQGAGTAGIVLPEKEEKVIAIKKGDSIALPFGVVTWWFNNEDTELVVLFLGETHKGHKAGQFTDFYLTGSNGIFTGFSTEFVGRAWDLDETTVKKLVGSQTGNGIVKVDASLKMPEPKKGDRKGFVLNCLEAPLDVDIKDGGRVVVLNTKNLPLVGEVGFGADLVRIDGHSMCSPGFSCDSALQVTYIVGGSGRVQIVGADGKRVLETHVKAGVLFIVPRFFVVSKIADSDGLSWFSIVTTPDPIFTHLAGRTSVWKALSPEVLQAAFKVDPEVEKAFRSKRTSDAIFFSPSN
Protein: Transcription factor PIF7 (Basic helix-loop-helix protein 72) (AtbHLH72) (bHLH 72) (Phytochrome-interacting factor 7) (Transcription factor EN 109) (bHLH transcription factor bHLH072) (Q570R7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor acting negatively in the phytochrome B signaling pathway under prolonged red light. Regulates PHYB abundance at the post-transcriptional level, possibly via the ubiquitin-proteasome pathway. May regulate the expression of a subset of genes by binding to the G-box motif.
Subcellular location: Nucleus. Note=Migrates rapidly to speckles upon light exposure.
Interaction partners:
- Phytochrome B
- Phytochrome A
- Two-component response regulator-like APRR1
- Protein MRG2
- Protein EARLY FLOWERING 3
- Probable indole-3-pyruvate monooxygenase YUCCA8
- Transcription factor HY5
- E3 ubiquitin-protein ligase COP1
- Phytochrome E
- Probable indole-3-pyruvate monooxygenase YUCCA9
Sequence:
MSNYGVKELTWENGQLTVHGLGDEVEPTTSNNPIWTQSLNGCETLESVVHQAALQQPSKFQLQSPNGPNHNYESKDGSCSRKRGYPQEMDRWFAVQEESHRVGHSVTASASGTNMSWASFESGRSLKTARTGDRDYFRSGSETQDTEGDEQETRGEAGRSNGRRGRAAAIHNESERRRRDRINQRMRTLQKLLPTASKADKVSILDDVIEHLKQLQAQVQFMSLRANLPQQMMIPQLPPPQSVLSIQHQQQQQQQQQQQQQQQQQFQMSLLATMARMGMGGGGNGYGGLVPPPPPPPMMVPPMGNRDCTNGSSATLSDPYSAFFAQTMNMDLYNKMAAAIYRQQSDQTTKVNIGMPSSSSNHEKRD
Protein: Coiled-coil domain-containing protein 121 (Q6ZUS5)
Organism: Homo sapiens (Human)
Interaction partners:
- TBC1 domain family member 17
- Spermatogenesis-associated protein 31H1
- Zinc finger protein 512
Sequence:
MTDLNKHIKQAQTQRKQLLEESRELHREKLLVQAENRFFLEYLTNKTEEYTEQPEKVWNSYLQKSGEIERRRQESASRYAEQISVLKTALLQKENIQSSLKRKLQAMRDIAILKEKQEKEIQTLQEETKKVQAETASKTREVQAQLLQEKRLLEKQLSEPDRRLLGKRKRRELNMKAQALKLAAKRFIFEYSCGINRENQQFKKELLQLIEQAQKLTATQSHLENRKQQLQQEQWYLESLIQARQRLQGSHNQCLNRQDVPKTTPSLPQGTKSRINPK
Protein: Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB) (Q9BV40)
Organism: Homo sapiens (Human)
Function: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex. Also required for dense-granule secretion in platelets. Also plays a role in regulated enzyme secretion in pancreatic acinar cells (By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells (By similarity). Involved in the homotypic fusion of early and late endosomes (By similarity). Participates also in the activation of type I interferon antiviral response through a TRIM6-dependent mechanism.
Subcellular location: Lysosome membrane {ECO:0000269|PubMed:25686604}; Single-pass type IV membrane protein {ECO:0000305}. Early endosome membrane {ECO:0000269|PubMed:25648148, ECO:0000269|PubMed:9614193}; Single-pass type IV membrane protein {ECO:0000305}. Late endosome membrane {ECO:0000269|PubMed:25648148}; Single-pass type IV membrane protein {ECO:0000305}. Cell membrane {ECO:0000250|UniProtKB:O70404}; Single-pass type IV membrane protein {ECO:0000305}. Zymogen granule membrane {ECO:0000250|UniProtKB:O70404}; Single-pass type IV membrane protein {ECO:0000305}. Note=Perinuclear vesicular structures of the early and late endosomes, coated pits, and trans-Golgi (By similarity). Sub-tight junctional domain in retinal pigment epithelium cells. Midbody region during cytokinesis. Lumenal oriented, apical membranes of nephric tubular cell (By similarity). Cycles through the apical but not through the basolateral plasma membrane (By similarity). Apical region of acinar cells; in zymogen granule membranes (By similarity). {ECO:0000250|UniProtKB:Q9WUF4}.
Interaction partners:
- Syntaxin-7
- Synaptosomal-associated protein 23
- Syntaxin-6
- Syntaxin-4
- Vesicle-associated membrane protein 7
- Synaptosomal-associated protein 29
- Syntaxin-3
- Vesicle transport through interaction with t-SNAREs homolog 1B
- Syntaxin-17
- Syntaxin-8
Sequence:
MEEASEGGGNDRVRNLQSEVEGVKNIMTQNVERILARGENLEHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVLICVIVFIIILFIVLFATGAFS
Protein: DOA4-independent degradation protein 4 (ESCRT-III complex subunit VPS2) (Vacuolar protein-sorting-associated protein 2) (Vacuolar protein-targeting protein 14) (P36108)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Acts a component of the ESCRT-III complex, which appears to be critical for late steps in MVB sorting, such as membrane invagination and final cargo sorting and recruitment of late-acting components of the sorting machinery. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complex assemblies. Can directly stimulate VPS4 ATPase activity. The DID4/VPS2-VPS24 subcomplex is required for the VPS4-dependent dissociation of ESCRT-III.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12194857}. Endosome membrane {ECO:0000269|PubMed:12194857}; Peripheral membrane protein {ECO:0000269|PubMed:12194857}.
Interaction partners:
- Vacuolar protein-sorting-associated protein 36
- Vacuolar protein-sorting-associated protein 46
- Vacuolar protein sorting-associated protein 4
- Vacuolar protein sorting-associated protein 20
- Vacuolar protein-sorting-associated protein 24
- Vacuolar protein-sorting-associated protein 25
- Vacuolar-sorting protein SNF7
- Vacuolar protein sorting-associated protein 28
- Vacuolar-sorting protein SNF8
- Vacuolar protein-sorting-associated protein 60
Sequence:
MSLFEWVFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDKKLVSEIKKSAKNGQVAAAKVQAKDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQMTRSMSEATGLLAGMNRTMNLPQLQRISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDEDEEADEIVNKVLDEIGVDLNSQLQSTPQNLVSNAPIAETAMGIPEPIGAGSEFHGNPDDDLQARLNTLKKQT
Protein: Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (O35550)
Organism: Rattus norvegicus (Rat)
Function: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium.
Subcellular location: Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Recycling endosome {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}.
Interaction partners:
- Rab5 GDP/GTP exchange factor
- Golgi associated, gamma adaptin ear containing, ARF binding protein 1
- Early endosome antigen 1
- Ras-related protein Rab-4A
- ADP-ribosylation factor-binding protein GGA3
- TRAF3-interacting protein 1
- Rabenosyn, RAB effector
- Golgi associated, gamma adaptin ear containing, ARF binding protein 2
- GTPase-activating protein and VPS9 domain-containing protein 1
- Ras-related protein Rab-5A
Sequence:
MAQPGPAPQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRAKFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERAQWAQYRESADREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKGKDNKKIDTEEEVKIPVVCALTQEESSTPLSNEEEHLDSTHGSVHSLDADLLLPSGDPFSKSDNDMFKEGLRRAQSTDSLGTSSSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFDTVSLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVQVLRELVLKYRENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLPET
Protein: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase (EC 2.4.1.135) (F8W289)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus membrane {ECO:0000256|RuleBase:RU363127}; Single-pass type II membrane protein {ECO:0000256|RuleBase:RU363127}. Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
- Hexosyltransferase.
- Hexosyltransferase
- Hexosyltransferase
- UDP-glucuronic acid decarboxylase 1
- Xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
- Hexosyltransferase
- Adenosine 3'-phospho 5'-phosphosulfate transporter 1
- Xylosyltransferase II.
- Xylosyltransferase I.
- Exostosin-like 3
Sequence:
MRMRLKLKTVFVLYFMVSLFGLLYALMQLGQRCDCRDHEQSKDQQISQLKGELQKLQEHIKTSELSKKTDVPRIYVITPTYARLVQKAELTRLSHTFLHVPQLHWIVVEDAPQQTQLVSDFLSASGLTYTHLNKLTPKERKLQEGDPNWLKPRGAEQRNEGLRWLRWMGSTVHGKEAAALEEAVVYFADDDNTYSLQLFEEMRYTYRVSVWPVGLVGGMKFERPVVEDGKVVRFHTGWRPNRPFPIDMAGFAVSLRLVLTNKEALFDGDAQMGFLESSFLQHLVTMDDLEPKADLCTKVLVWHTRTEKPKMKREEALLKQGMGSDPDVEV
Protein: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase) (Q9DBL1)
Organism: Mus musculus (Mouse)
Function: Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (By similarity). Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway (By similarity). Can also act on valproyl-CoA, a metabolite of the valproic acid drug (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:P45954}.
Interaction partners:
- Trifunctional enzyme subunit beta, mitochondrial
- Enoyl-CoA hydratase, mitochondrial
- 3-ketoacyl-CoA thiolase A, peroxisomal
- 3-ketoacyl-CoA thiolase B, peroxisomal
- Trifunctional enzyme subunit alpha, mitochondrial
- Peroxisomal bifunctional enzyme
- 3-ketoacyl-CoA thiolase, mitochondrial
- Acetyl-CoA acetyltransferase, cytosolic
- Acetyl-CoA acetyltransferase, mitochondrial
- Peroxisomal acyl-coenzyme A oxidase 1
Sequence:
MAVSALQLWRMGGLLRRRFPTCLSPWKIPPRVLKSSQPEALVSLTNNAVAFAPLQTLTDEEIMMKQTVKKFAQEHVAPLVSSMDENSKMEKSVIQGLFQQGLMGIEVEAQYGGTEASFFCSVLVIEELAKVDASVALLCDIQNTIINNLFRKHASEEQKATYLPKLVTEKLGSFCLSEAGAGSDSFAMKTRADKSGNYYVLNGSKMWISHAEHAELFLVFANVDPSSGYRGITCFLVDRDTEGFQIGKRENKMGIRASSTCQLTFENVKVPETNILGKIGHGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERMQFGKRIFDFQGLQHQVAQVATQLEATRLLTYNAARLVEAGRPFIKEASMAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKIGTIYEGASNIQLNTIAKHIDAEY
Protein: Erythrocyte binding antigen-181 (Q8I2B4)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Histone H4
Sequence:
MKGKMNMCLFFFYSILYVVLCTYVLGISEEYLKERPQGLNVETNNNNNNNNNNNSNSNDAMSFVNEVIRFIENEKDDKEDKKVKIISRPVENTLHRYPVSSFLNIKKYGRKGEYLNRNSFVQRSYIRGCKGKRSTHTWICENKGNNNICIPDRRVQLCITALQDLKNSGSETTDRKLLRDKVFDSAMYETDLLWNKYGFRGFDDFCDDVKNSYLDYKDVIFGTDLDKNNISKLVEESLKRFFKKDSSVLNPTAWWRRYGTRLWKTMIQPYAHLGCRKPDENEPQINRWILEWGKYNCRLMKEKEKLLTGECSVNRKKSDCSTGCNNECYTYRSLINRQRYEVSILGKKYIKVVRYTIFRRKIVQPDNALDFLKLNCSECKDIDFKPFFEFEYGKYEEKCMCQSYIDLKIQFKNNDICSFNAQTDTVSSDKRFCLEKKEFKPWKCDKNSFETVHHKGVCVSPRRQGFCLGNLNYLLNDDIYNVHNSQLLIEIIMASKQEGKLLWKKHGTILDNQNACKYINDSYVDYKDIVIGNDLWNDNNSIKVQNNLNLIFERNFGYKVGRNKLFKTIKELKNVWWILNRNKVWESMRCGIDEVDQRRKTCERIDELENMPQFFRWFSQWAHFFCKEKEYWELKLNDKCTGNNGKSLCQDKTCQNVCTNMNYWTYTRKLAYEIQSVKYDKDRKLFSLAKDKNVTTFLKENAKNCSNIDFTKIFDQLDKLFKERCSCMDTQVLEVKNKEMLSIDSNSEDATDISEKNGEEELYVNHNSVSVASGNKEIEKSKDEKQPEKEAKQTNGTLTVRTDKDSDRNKGKDTATDTKNSPENLKVQEHGTNGETIKEEPPKLPESSETLQSQEQLEAEAQKQKQEEEPKKKQEEEPKKKQEEEQKREQEQKQEQEEEEQKQEEEQQIQDQSQSGLDQSSKVGVASEQNEISSGQEQNVKSSSPEVVPQETTSENGSSQDTKISSTEPNENSVVDRATDSMNLDPEKVHNENMSDPNTNTEPDASLKDDKKEVDDAKKELQSTVSRIESNEQDVQSTPPEDTPTVEGKVGDKAEMLTSPHATDNSESESGLNPTDDIKTTDGVVKEQEILGGGESATETSKSNLEKPKDVEPSHEISEPVLSGTTGKEESELLKSKSIETKGETDPRSNDQEDATDDVVENSRDDNNSLSNSVDNQSNVLNREDPIASETEVVSEPEDSSRIITTEVPSTTVKPPDEKRSEEVGEKEAKEIKVEPVVPRAIGEPMENSVSVQSPPNVEDVEKETLISENNGLHNDTHRGNISEKDLIDIHLLRNEAGSTILDDSRRNGEMTEGSESDVGELQEHNFSTQQKDEKDFDQIASDREKEEIQKLLNIGHEEDEDVLKMDRTEDSMSDGVNSHLYYNNLSSEEKMEQYNNRDASKDREEILNRSNTNTCSNEHSLKYCQYMERNKDLLETCSEDKRLHLCCEISDYCLKFFNPKSIEYFDCTQKEFDDPTYNCFRKQRFTSMHYIAGGGIIALLLFILGSASYRKNLDDEKGFYDSNLNDSAFEYNNNKYNKLPYMFDQQINVVNSDLYSEGIYDDTTTF
Protein: Interferon C (C1IRX8)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MPCQLQGQLVRITHNLLRDMGGNFPLECLQENVFMAFPATAFASSGAPQLGSSGAKAIYETLKNIDILFEADDPPTQWDQQKLENFQNIVYRQIEESKCMMGSVDTSDYLIRTEGLNTYFGNIAAVLKEKNFSYC