wanglab/gogpt-training-data huggingface dataset:
Protein: Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (P12887)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Not involved in strand-directed mismatch repair.
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03166, ECO:0000269|PubMed:11812822}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03166, ECO:0000269|PubMed:11812822}.
Interaction partners:
- Apurinic-apyrimidinic endonuclease 1
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- DNA-
- N-glycosylase/DNA lyase
- Endonuclease III homolog 2 lyase 2)
- Endonuclease III homolog 1 lyase 1)
- Proliferating cell nuclear antigen
- Cytidine deaminase
- DNA repair protein REV1
- Flap endonuclease 1
Sequence:
MWCMRRLPTNSVMTVARKRKQTTIEDFFGTKKSTNEAPNKKGKSGATFMTITNGAAIKTETKAVAKEANTDKYPANSNAKDVYSKNLSSNLRTLLSLELETIDDSWFPHLMDEFKKPYFVKLKQFVTKEQADHTVFPPAKDIYSWTRLTPFNKVKVVIIGQDPYHNFNQAHGLAFSVKPPTPAPPSLKNIYKELKQEYPDFVEDNKVGDLTHWASQGVLLLNTSLTVRAHNANSHSKHGWETFTKRVVQLLIQDREADGKSLVFLLWGNNAIKLVESLLGSTSVGSGSKYPNIMVMKSVHPSPLSASRGFFGTNHFKMINDWLYNTRGEKMIDWSVVPGTSLREVQEANARLESESKDP
Protein: Cyclic dof factor 4 (Dof zinc finger protein DOF2.3) (AtDOF2.3) (O22967)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Transcriptional repressor of 'CONSTANS' expression (By similarity). Regulates a photoperiodic flowering response.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- WUSCHEL-related homeobox 5
- CLAVATA3/ESR
- BRCA1-associated RING domain protein 1
Sequence:
MATQDSQGIKLFGKTIAFNTRTIKNEEETHPPEQEATIAVRSSSSSDLTAEKRPDKIIACPRCKSMETKFCYFNNYNVNQPRHFCKGCHRYWTAGGALRNVPVGAGRRKSKPPGRVVVGMLGDGNGVRQVELINGLLVEEWQHAAAAAHGSFRHDFPMKRLRCYSDGQSC
Protein: T-cell surface protein tactile (Cell surface antigen CD96) (T cell-activated increased late expression protein) (CD antigen CD96) (Q3U0X8)
Organism: Mus musculus (Mouse)
Function: May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation (By similarity).
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Poliovirus receptor
Sequence:
MGRKWTYCVVYTIIQIQFFRGVWEELFNVGDDVYALPGSDINLTCQTKEKNFLVQMQWSKVTDKNDMIALYHPQYGLYCGQEHACESQVAATETEKGVTNWTLYLRNISSALGGKYECIFTLYPEGIKTTVYNLIVEPYTQDEHNYTIEIETNRTLEIPCFQNTSSEIPPRFTFSWLVEKDGVEEVLFTHHHHVNNSTSFKGRIRLGGDYRLHLSPVQIQDDGRTFSCHLTVNPLKAWKMSTTVKVFAKPEILMTVENSTMDVLGERVFTCLLKNVFPKANITWFIDGRFLQGNEEGIYITNEEKNCSSGFWELKSVLTRMHSGPSQSNNMTAWCMALSPGPRNKMWNTSSQPITVSFDSVIAPTKHLPTVTGSTLGTQPFSDAGVSPTGYLATPSVTIVDENGLTPDATPQTSNSSMTTKDGNYLEASSGTDAKNSSRAAASSKSGSWPFPFTSPPEWHSLPGTSTGPQEPDSPVSWIPSEVHTSAPLDASLAPHDTIISTTTEFPNVLTTANGTTKIDHGPITSIIVNQPSDGMSWPVLVAALLFFCTLLFGLGVRKWYRYQNEIMERPPPFKPPPPPIKYTYIQEPIGCDLCCHEMEVL
Protein: Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2) (Q924U5)
Organism: Rattus norvegicus (Rat)
Function: Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Hypothetical gene supported by BC079265
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L1
- Adhesion G protein-coupled receptor L2
Sequence:
MDRSKRNSIAGFPPRVERLEEFEGGGGGDGNTVQVGRVSSSSYRAIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSRLQEEELERDRKLQPTAKGLLEKVPGGKRLSSLDDKIPHKSPRPRRTIWLSRSQSDIFSRKPPRTVNVLDPYYQPRDGATHTPKVNPFSARQDLKGGKVKFFDLPSKSVISLVFDLDAPGPGTVSLADCQEPLAPSSRRWRSLPGSPEFLHQACPFVGCEESLSDGPPPRLSSLKYRVREIPPFRTSALSATSAHEAMDCSNPQEENGFVPRPKGTSPCSGAASEEMEVEEERPRRAPVHFSISGISLQTQGEQDG
Protein: N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6) (Q9CWY3)
Organism: Mus musculus (Mouse)
Function: Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (By similarity). Required for the maintenance of embryonic stem cell self-renewal. Methylates PAK4.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8TBK2}.
Interaction partners:
- Transcription factor p65
- RNA-binding protein NOB1
Sequence:
MAAPAKRARVSGGSPLVAPCPSPRAARAPLPLPAGSSGGEPEGDAVAGFLRWCRRVGLELSPKVTVSRQGTVAGYGMVARESVRAGELLFAVPRSALLSPHTCSISGLLERERGALQSLSGWVPLLLALLHELQAPASPWSPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPSVRSLELYQQLVALVMAYSFQEPLEEDDDEKEPNSPLMVPAADILNHIANHNANLEYSADYLRMVATQPILEGHEIFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVTVRDAALQGTKDETEKLLVCERWDFLCKQEMVGEEGAFVIGCEEVLTEEELATTLKVLCMPAEEFRDYKERAGWGEEETEDDSLAITDIPKLQESWKRLLRNSVLLTLQTYTTDLKTDQDLLSNKEAYATLSWREQQALQVRYGQKMILHRVLELTN
Protein: Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit) (P48508)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Glutamate--cysteine ligase catalytic subunit
- Glutathione synthetase
- 5-oxoprolinase
- Aminopeptidase N
- Gamma-glutamylcyclotransferase
- Glutathione hydrolase 6
- Glutathione hydrolase 7
- Glutathione hydrolase 5 proenzyme
- Alanine--glyoxylate aminotransferase 2, mitochondrial
- NAD
Sequence:
MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLVREFPDVLECTMSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRNAVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAQEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRKGS
Protein: Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (EC 3.1.4.17) (63 kDa Cam-PDE) (Q01061)
Organism: Bos taurus (Bovine)
Function: Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q01064}.
Interaction partners:
- EF-hand calcium-binding domain-containing protein 11
- Calmodulin
- CALML5 protein
- Calmodulin-like protein 4
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- Adenosine kinase
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
- Inosine triphosphate pyrophosphatase
- Adenine phosphoribosyltransferase
Sequence:
MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLEYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQTRAKGPSEEKPKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNVDLWCFDVFSLNRAADDHALRTIVFELLTRHNLISRFKIPTVFLMTFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKSMKTALQQLERIDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPTGDDDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPASPAEDEHNQNGNLD
Protein: Solute carrier family 26 member 2 (Sulfate transporter) (E7F9I7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Solute carrier family 13
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- Glucose-6-phosphate exchanger SLC37A1
Sequence:
MPTEGSCNNLSAEEDAKREPNLPFRLEECVKEKVSWKEALRKKVKKCSCSTARVKSQIMKSFPIVKWLPRYRFKDWIIGDAMSGLIVGILLVPQSIAYSLLAGQDPIYGLYTSFFANIIYALLGTSRHISVGMFGVLCLLVGQVVDRELTLAGYSSDINQTTLGNVDNSTGPICDRSCYAIMVGATLTFTAGIYQVLMGLLQIGFVSVFLSDSLLSGFATGASLTILTSQIKYFLGLHLPRVQGWGSLIKTWISLFKNLGHTNLCDLITSLICLLVLVPAKELNDRFKAKLKAPIPFELFVVIAATLASHFGHFKDTYGSDVAGTIPTGFMAPQSPNLSLVPNIAIDALSIAIVGFAITVSLSEMFAKKHGYIVNANQELNAIGNCNIISSYFHCFTVSAALTKTLVKESTGCHTQISGLVTALVLLLVMLVIAPAFYSLQKCVLAVIIVVNLRGALRKFGDIPQMWRVNRVDTVIWLLTMATSALVNTELGLLVGVVVSAFCVLGRTQFAQALQLGQAGDRELFEDIASYNGLQTQPDVAVFRYEAPIYYANQSLFKKSLYRNVGLDPLKEKAKQRKLEKQRKQKHSREDQKQEMDASTNVNLLQHSSFHTLVIDCSSVLFLDTAGVNALKEVFKDYKELGVNVLLAQCNTSVIDSLRRGDYYDPNKGTKDIQFHTIGEAILYGQSLKSQNGNCDTSV
Protein: Tropomyosin 3 (Tropomyosin alpha-3 chain isoform X1) (I3ISQ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Slow troponin T
- Troponin T type 1
- Troponin T type 2a
- Actin alpha 1, skeletal muscle a.
- Novel slow skeletal troponin T family protein
- Troponin T2d, cardiac.
- Actin alpha cardiac muscle 1a
- Myosin, light chain 1, alkali; skeletal, fast
- Troponin T type 2b
- Actin alpha cardiac muscle 1b
Sequence:
MEAVKKKMMMLKLDKENALDQAEQAETDRKAAEERSKQHEDELIQMQKKLKGTEDELDKYSEALKDAQEKLEISEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELAESKCAELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEEKLRDAKEENIKIHATLDQTLSELNSF
Protein: Optomotor-blind-related-gene-1, isoform A (Optomotor-blind-related-gene-1, isoform B) (Q9W3F4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Protein max
- GH02722p
- histone acetyltransferase
- Transcriptional coactivator yorkie
- Muscle-specific homeobox protein tinman
Sequence:
MTHLMGPTECAGAMMTTTSMQFLDTSLTDYNCYGNDYWTSPYMTGGLSPMKQIEACIQTAGKDRSSYKPLEQIDAKLADIETHSTGSTGTANSNSSTSSISNPSCPDQSSSSSSSSVSLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVKPNSHNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQLKERTAATSNFGLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQQHQQQQQQQHQSQQQHLHQQHQANQQQSLLQQSQNHTQYGSYHHAYQAQVQSHPLTPHSSSSASPPATAAPGASAATAAVAGGAGAAGAGGATSATQVMSAANIYSSIGQPYAQEQSNFGAIYHHNAAAAAAAHYHHGHAHGHAHSHAHAHAHGPYASAYDKLKVSRHAAAAAYGMGATYPSFYGSAAHHQMMRPNSYIDLVPR
Protein: Proteasome subunit alpha type-6 (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain) (Proteasome subunit alpha-1) (alpha-1) (Q9QUM9)
Organism: Mus musculus (Mouse)
Function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22078707}. Nucleus {ECO:0000269|PubMed:22078707}. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9 (By similarity). Colocalizes with TRIM5 in cytoplasmic bodies (PubMed:22078707). {ECO:0000250|UniProtKB:P60900, ECO:0000269|PubMed:22078707}.
Interaction partners:
- Proteasome subunit beta type-9
- 26S proteasome regulatory subunit 8
- Proteasome subunit alpha type-7
- Proteasome subunit alpha type-2
- Proteasome subunit beta type-10
- Proteasome subunit alpha type-1
- Proteasome subunit alpha type-3
- Proteasome subunit beta type-2
- Proteasome subunit beta type-3
- Proteasome subunit beta type-5
Sequence:
MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD
Protein: Phosphatidylinositol-3-phosphate phosphatase MTMR1 (EC 3.1.3.-) (Myotubularin-related protein 1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (Q9Z2C4)
Organism: Mus musculus (Mouse)
Function: Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate. Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been shown for the human ortholog (By similarity). In contrast, PubMed:12217958 find no activity with this substrate.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12217958}; Peripheral membrane protein {ECO:0000269|PubMed:12217958}; Cytoplasmic side {ECO:0000269|PubMed:12217958}. Cytoplasm {ECO:0000269|PubMed:12217958}.
Interaction partners:
- Polyphosphoinositide phosphatase
- 1-phosphatidylinositol 3-phosphate 5-kinase
- Phosphatidylinositol-3-phosphatase SAC1
- Inositol polyphosphate-4-phosphatase type I A
- Type II inositol 3,4-bisphosphate 4-phosphatase
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Phosphatidylinositide phosphatase SAC2
- Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
- Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
Sequence:
MDRPVAAAAAASAASCEGAGGPGPGPGASWRPSRVAGGASASSRHPSIETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVIYICPFMGAVSGTLTVTDFKMYFKNVERDPHFVLDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFPLSNGQVLFAFNYKEKFPVNGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLTIFDARQNSVADTNKAKGGGYENESAYPNAELIFLEIHNIHVMRESLRKLKEIVYPSIDESHWLSNVDGTHWLEYIRVLLAGAVRIADKIESGKTSVVIHCSDGWDRTSQLTSLAMLMLDSYYRTIKGFEALIEKEWISFGHRFALRVGHGDDNHADADRSPIFLQFIDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRIKEDVYTNTISLWSYINSQLDEFSNPFFVNYENHVLYPVASMSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAIKAELQKRVEDLQREMATRTISSSSERGSSPTHSATPVHTSV
Protein: Acireductone dioxygenase 3 (Acireductone dioxygenase (Fe(2+)-requiring) 3) (ARD' 3) (Fe-ARD 3) (EC 1.13.11.54) (Acireductone dioxygenase (Ni(2+)-requiring) 3) (ARD 3) (Ni-ARD 3) (EC 1.13.11.53) (Q8W108)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03154}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03154}.
Interaction partners:
- Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1
- Aromatic aminotransferase ISS1
- At1g77670
- Acireductone dioxygenase 4-requiring) 4)
- Acireductone dioxygenase 2-requiring) 2)
- Acireductone dioxygenase 1-requiring) 1)
- GDSL esterase/lipase At1g58430
- Tyrosine aminotransferase
- Probable aminotransferase TAT3
- Probable aminotransferase TAT2
Sequence:
MGEVVKDGREEVIQAWYMDDSEEDQRLPHHKDPKEFLSLDKLAELGVLSWRLDADNYETDEDLKKIRESRGYSYMDFCEVCPEKLPNYEVKVKSFFEEHLHTDEEIRYCVAGSGYFDVRDRNEAWIRVWVKKGGMIVLPAGIYHRFTVDSDNYIKAMRLFVGEPVWTPYNRPHDHLPARKEYIDNFVKVNEGGVIDASA
Protein: Cilia- and flagella-associated protein 251 (Q57ZE4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}.
Interaction partners:
Sequence:
MAYSTRVIRKVEPSSTHESLALEWAFGLHNDYKANIHNLSTSTTERVVFYTVGHVGVIYDAIQNTQKHLMGHRHMIVASACSRNRRFIVTADSGSTKSSDCQDACGRSASGNHSTAGGAGEKSGVERYNNESAVIAPEGIYSSNEGRDATMIIWDVQTAIPIRKINTGEYGGVVACAMSLDGMYIATLNRTVPQEIMVWGWTADADTGAEVMRNGADEDPLLHDSMAPEYRHLIAAQDEQISIRFSDDDPHLIVTNGQYRVLFWSWAEGKLKYYSPPIIAKNFKVPIGHFTQTVFVPGTTMACSGTVDGDVLLWEVQQRDRVTKEQDKTMLKMVRVHSSGVSFLTWSNGYIVTGGIDGDVKFLDPRLRLVAWFEDLKGGAITSISFDRPSGTAATAVNELRREFKSITQKKMVQVGTNAVGDFSASDFMVSTSNAMIIDVSANAFHAGVPELLRGRLVVQGQENGVHCIAAHPKLSRLAVAGHSGGLQVWDYLLKRVVMIVVFRGVEINCMAFDPEGVWLAIGCTNGVVKFLDSANLEERKSIKPKRPSSITRMVFASSGRLLATGDDTGCVSLFWYEHIQGNTSKAMGWDVVGRHKTHKGTITGLQFGDDSGLHRLLSVGEDQRLVEYDLIDSEPETGLLVRSAHKIAQSSTPTGFLWMDEDGIISDVSRRPDAAHTITNGLLIANSGYKISAYFSDWSRQCVKTVLAPTFGGPVTEMFTVPTHPGSDKSSLFYATKEKVIGFIQLPLEGDPCLSMGLLAHAGPITSVAKSYDGAYVFTAGGLDQSVMQWRVNGNKIVPEEASKISASVAAEGNGEVPLDHLIAVVEGGREGEFMREIVDYFYYAQIRLQGEETTAKRELLGAVPFSQVPNLFRALGYYPTEMELGRLTYEVANLYGPVEESVDECDVSSIPLKFSQFMRLYVNYRPIFGISRQAVEQAFLVLGADALTGQISRDVLFKKLTTHGEPLQQTEITAALRSLLGEDVKLDDIQDTITARLFAENLLGFEDYDAMAQGDDGGEEEMSLQ
Protein: Adhesion G protein-coupled receptor B2 (A2A3C6)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MLSLRGPDTHGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQAESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEPGLYMAQTVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSADDVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGEPPPPQEANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEGTPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGERSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPRERLTLHRAAAWEPTEPPDGDFQTEV
Protein: 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (DAROPP reductase) (DARP reductase) (EC 1.1.1.302) (2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase) (2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase) (DARIPP synthase) (P33312)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
Interaction partners:
- Bifunctional protein RIB2
- GTP cyclohydrolase-2
- Riboflavin synthase
- 6,7-dimethyl-8-ribityllumazine synthase
- 3,4-dihydroxy-2-butanone 4-phosphate synthase
- Riboflavin kinase
- Flavin adenine dinucleotide synthase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
Sequence:
MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRTTISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKWGPDPAANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQHVDYAICPINDTTKLVDWKKLFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSLIITIGSTFLGSSGTEVSPPQTVNLKDMSWWKGITDVVLCARLADD
Protein: Metallo-beta-lactamase superfamily protein (O69645)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MSKTAESLTHPAYGQLRAVTDTASVLLADNPGLLTLDGTNTWVLRGPLSDELVVVDPGPDDDEHLARVAALGRIALVLISHRHGDHTSGIDKLVALTGAPVRAADPQFLRRDGETLTDGEVIDVAGLTITVLATPGHTADSLSFVLDDAVLTADTVLGCGTTVIDKEDGSLADYLESLHRLRGLGRRTVLPGHGPDLLDLEAIASGYLLHRHERLEQIRAALRDLGDDATVREVVEHVYLDVDEKLWNAAEWSVQAQLDYLRTR
Protein: Endophilin-A3b isoform X1 (SH3-domain GRB2-like 3b) (A0A2R8QD99)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Early endosome {ECO:0000256|ARBA:ARBA00004412}. Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
Sequence:
MSVAGFKKQFHKASQLLKEKINGVEGTKLDEEFLSMERKTEITHKLILDIVPKTIGYLQPNPAYRAKLSMLSTVSRIRGHVKAVGYPQTEGILGDCMLQYGSELGAESGFGFALLEMGEALKQVAQARDCMDVRVKRAFIDPLQSLQQKELKEIGFHLRKLEGRRLDFDYKKRRKGKIADSEIKKAFDKFEESKEMAERCMFNLLEKDVQRMQHLSGLLEAVIDYHRQSSQILENLRSNLQTKIRDASNKPKREFASKSVASTVCYSDIYGFSTCSSGPSSDAPVVVHRPEQVTIKTPTTDKPASINDRAPPLDQPCCQALYSFQAENQGELGFKEGDIIILTSQIDENWYEGMIRGQSGLFPMNYVKVLVPLPQ
Protein: U6 snRNA phosphodiesterase (EC 3.1.4.-) (H3BTT8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|HAMAP-Rule:MF_03040}.
Interaction partners:
Sequence:
MSPRTGCGPGRGMGATVGEDGQSPLPRQRFPVPDSVLNMFPGTEEGPEDDSTKHGGRVRTFPHERGNWATHVYVPYEAKEEFLDLLDVLLPHAQTYVPRLVRMKVFHLSLSQSVVLRHHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTSGHAQFLDLVSEVDRVMEEFNLTTFYQDPSFHLSLAWCVGDARLQLEGQCLQELQAIVDGFEDAEVLLRVHTEQVRCKSGNKFFSMPLK
Protein: Mitochondrial carrier homolog 1 (Mitochondrial carrier-like protein 1) (Q791T5)
Organism: Mus musculus (Mouse)
Function: Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (By similarity). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). May play a role in apoptosis (By similarity).
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9NZJ7}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGASDPEVAPWAPGGAAGMAGAGAGAGARGGAPAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGPGAPGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLRAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE