wanglab/gogpt-training-data huggingface dataset:
Protein: Ribosome-binding ATPase YchF (P0ABU2)
Organism: Escherichia coli (strain K12)
Function: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. Does not hydrolyze GTP.
Interaction partners:
- Peptidyl-tRNA hydrolase
- Probable GTP-binding protein EngB
- Elongation factor 4
- GTPase Der
- Peptide chain release factor RF1
- Low specificity L-threonine aldolase
- GTPase HflX
- Elongation factor G
- Glutamate--tRNA ligase
- Arginine--tRNA ligase
Sequence:
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKAELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKLLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQGAKEAGKMRAEGKDYIVKDGDVMNFLFNV
Protein: MIA SH3 domain ER export factor 3 (A0A0A0MRH6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XLVPDSKQGKPQSATDYSDPDNVDDGLFIVDIPKTNNDKEVNAEHHIKGKGRGVQESKRGLVQDKTELEDENQEGMTVHSSVHSNNLNSMPAAEKGKDTLKSAYDDTENDLKGAAIHISKGMLHEEKPGEQILEGGSESESAQKAAGNQMNDRKIQQESLGSAPLMGDDHPNASRDSVEGDALVNGAKLHTLSVEHQREELKEELVLKTQNQPRFSSPDEIDLPRELEDEVPILGRNLPWQQERDVAATASKQMSEKIRLSEGEAKEDSLDEEFFHHKAMQGTEVGQTDQTDSTGGPAFLSKVEEDDYPSEELLEDENAINAKRSKEKNPGNQGRQFDVNLQVPDRAVLGTIHPDPEIEESKQETSMILDSEKTSETAAKGVNTGGREPNTMVEKERPLADKKAQRPFERSDFSDSIKIQTPELGEVFQNKDSDYLKNDNPEEHLKTSGLAGEPEGELSKEDHENTEKYMGTESQGSAAAEPEDDSFHWTPHTSVEPGHSDKREDLLIISSFFKEQQSLQRFQKYFNVHELEALLQEMSSKLKSAQQESLPYNMEKVLDKVFRASESQILSIAEKMLDTRVAENRDLGMNENNIFEEAAVLDDIQDLIYFVRYKHSTAEETATLVMAPPLEEGLGGAMEEMQPLHEDNFSREKTAELNVQVPEEPTHLDQRVIGDTHASEVSQKPNTEKDLDPGPVTTEDTPMDAIDANKQPETAAEEPASVTPLENAILLIYSFMFYLTKSLVATLPDDVQPGPDFYGLPWKPVFITAFLGIASFAIFLWRTVLVVKDRVYQVTEQQISEKLKTIMKENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEKNQEILDDTAKNLRVMLESEREQNVKNQDLLQQEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDDNINALTNCITQLNLLECESESEGQNKGGNDSDELANGEVGGDRNEKMKNQIKQMMDVSRTQTAISVVEEDLKLLQLKLRASVSTKCNLEDQ
Protein: NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (RUB1-activating enzyme E1) (Ubiquitin-activating enzyme E1 3) (Ubiquitin-like protein-activating enzyme) (Q99344)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalytic subunit of the dimeric UBA3-ULA1 E1 enzyme. E1 activates NEDD8/RUB1 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBC12.
Interaction partners:
- NEDD8-conjugating enzyme UBC12
- NEDD8-activating enzyme E1 regulatory subunit
- NEDD8-like protein RUB1
- Ubiquitin-activating enzyme E1 1
- RING-box protein HRT1
- COP9 signalosome complex subunit 5
- Defective in cullin neddylation protein 1
- Tyrosine--tRNA ligase, mitochondrial
- Cullin-3
- Ubiquitin carboxyl-terminal hydrolase YUH1
Sequence:
MDCKILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTRFPQLEVVAHVQDLTTLPPSFYKDFQFIISGLDAIEPRRFINETLVKLTLESNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIANNPRCIEHVVEYVSTIQYPDLNIESTADMEFLLEKCCERAAQFSISTEKLSTSFILGIIKSIIPSVSTTNAMVAATCCTQMVKIYNDLIDLENGNNFTLINCSEGCFMYSFKFERLPDCTVCSNSNSN
Protein: AGAMOUS-like 71 (F4KEP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNLGMNIAGTMVRGKIEIKKIENVTSRQVTFSKRRSGLFKKAHELSVLCDAQVAAIVFSQSGRLHEYSSSQMEKIIDRYGKFSNAFYVAERPQVERYLQELKMEIDRMVKKIDLLEVHHRKLLGQGLDSCSVTELQEIDTQIEKSLRIVRSRKAELYADQLKKLKEKERELLNERKRLLEEQNRERLMRPVVPATLQICDKGNTEGGHRTKHSSEVETDLFIGLPVTRL
Protein: Cwt1p (Q59M50)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Oleate-activated transcription factor
Sequence:
MSTMSTQKANSSTPGETDSSSSLPPPEITEPTYKKPEKSTKRRKKKLEIACVYCRRSHMICDESRPCQRCIKRGIAHLCYDEPSNSRQRKKAAALRKTQSEGAPMVTSPITLPLTGSTGNQSPLPLPPLQASQSDIRSAPKTENSLQFSQPALHQQQMQENPQGASQSVHTNNTHIYSSQNQQQQPQHQQQLQQQQPQPQPQSRLIKNSVLSQTLPYNQQPFFYSEHANSEFSSLNDFLSMIDDPELVNGALNDDTDGLLNFGVGNNNNSGGSNSNINNTHNNNNNGFSISGGNSTTNLNAVLAYSPNSNLFPPTFGNEADSTQIQSQQQQPELTQQPPALNPVKVEPQAEKTEQQPVISDSARDKFFLTAADPTTEISPEERLKQVIKAKLEAGLLQPYNYAKGYARLQRYMDNYMNISSRQRILKPLSIFRPAFRAIARTLKDVDLVLVEESFERMLLDYDRVFTAMAIPACLWRRTGEIYRGNKEFASLVGVTTDDLKDGKLAIYELMSEESAVNFWEKYGAIAFDKGQKAVLTSCNLRTRDGIKRKSCCFSFTIRRDRYNIPSCIVGNFIPIDP
Protein: Myosin tail region-interacting protein MTI1 (Protein BBC1) (P47068)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the regulation of actin cytoskeleton.
Subcellular location: Cytoplasm, cytoskeleton, actin patch {ECO:0000269|PubMed:11901111}. Note=Colocalizes with cortical actin patches.
Interaction partners:
- Protein BZZ1
- Proline-rich protein LAS17
- Myosin-3
- Reduced viability upon starvation protein 167
- Verprolin
- Altered inheritance of mitochondria protein 21
- Myosin-5
- Actin cytoskeleton-regulatory complex protein SLA1
- Protein YSC84
- LAS seventeen-binding protein 1
Sequence:
MSEPEVPFKVVAQFPYKSDYEDDLNFEKDQEIIVTSVEDAEWYFGEYQDSNGDVIEGIFPKSFVAVQGSEVGKEAESSPNTGSTEQRTIQPEVEQKDLPEPISPETKKETLSGPVPVPAATVPVPAATVPVPAATAVSAQVQHDSSSGNGERKVPMDSPKLKARLSMFNQDITEQVPLPKSTHLDLENIPVKKTIVADAPKYYVPPGIPTNDTSNLERKKSLKENEKKIVPEPINRAQVESGRIETENDQLKKDLPQMSLKERIALLQEQQRLQAAREEELLRKKAKLEQEHERSAVNKNEPYTETEEAEENEKTEPKPEFTPETEHNEEPQMELLAHKEITKTSREADEGTNDIEKEQFLDEYTKENQKVEESQADEARGENVAEESEIGYGHEDREGDNDEEKEEEDSEENRRAALRERMAKLSGASRFGAPVGFNPFGMASGVGNKPSEEPKKKQHKEKEEEEPEQLQELPRAIPVMPFVDPSSNPFFRKSNLSEKNQPTETKTLDPHATTEHEQKQEHGTHAYHNLAAVDNAHPEYSDHDSDEDTDDHEFEDANDGLRKHSMVEQAFQIGNNESENVNSGEKIYPQEPPISHRTAEVSHDIENSSQNTTGNVLPVSSPQTRVARNGSINSLTKSISGENRRKSINEYHDTVSTNSSALTETAQDISMAAPAAPVLSKVSHPEDKVPPHPVPSAPSAPPVPSAPSVPSAPPVPPAPPALSAPSVPPVPPVPPVSSAPPALSAPSIPPVPPTPPAPPAPPAPLALPKHNEVEEHVKSSAPLPPVSEEYHPMPNTAPPLPRAPPVPPATFEFDSEPTATHSHTAPSPPPHQNVTASTPSMMSTQQRVPTSVLSGAEKESRTLPPHVPSLTNRPVDSFHESDTTPKVASIRRSTTHDVGEISNNVKIEFNAQERWWINKSAPPAISNLKLNFLMEIDDHFISKRLHQKWVVRDFYFLFENYSQLRFSLTFNSTSPEKTVTTLQERFPSPVETQSARILDEYAQRFNAKVVEKSHSLINSHIGAKNFVSQIVSEFKDEVIQPIGARTFGATILSYKPEEGIEQLMKSLQKIKPGDILVIRKAKFEAHKKIGKNEIINVGMDSAAPYSSVVTDYDFTKNKFRVIENHEGKIIQNSYKLSHMKSGKLKVFRIVARGYVGW
Protein: Interferon-induced GTP-binding protein Mx2 (Myxovirus resistance protein 2) (Q9WVP9)
Organism: Mus musculus (Mouse)
Function: Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV) and Hantaan virus (HNTV).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10233954}.
Interaction partners:
Sequence:
MVLSTEENTGVDSVNLPSGETGLGEKDQESVNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLRKLNEGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDRGTEDKVVDVVRNLVYHLKKGYMIVKCRGQQDIQEQLSLTEALQNEQIFFKEHPHFRVLLEDGKATVPCLAERLTAELISHICKSLPLLENQIKESHQSASEELQKYGMDIPEDDSEKTFFLIEKINAFNQDITALVQGEENVAEGECRLFTRLRKEFLSWSKEIEKNFAKGYAVLYNEVWAFEKQYRGRELPGFVNYKTFENIIRRQIKTLEEPAIEMLHTVTEIVRAAFTSVSEKNFSEFYNLHRTTKSKLEDIRLEQEKEAEMSIRLHFKMEQIIYCQDQIYRGALQKVREEEAEEEKKTKHGTSSSSQSQDLQTSSMAEIFQHLNAYRQEAHNRISSHVPLIIQYFILKMFAERLQKGMLQLLQDKDSCSWLLKEQSDTSEKRKFLKERLARLAQARRRLAKFPG
Protein: Putative glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit) (O94246)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glutamate--cysteine ligase
- Glutathione synthetase large chain
- Glutathione hydrolase proenzyme 1
- Uncharacterized protein C11D3.15
- Uncharacterized protein C11D3.14c
- Cys-Gly metallodipeptidase dug1
- Cysteine synthase 2
- Branched-chain-amino-acid aminotransferase, mitochondrial
- Putative aminopeptidase C13A11.05
- Glutathione hydrolase proenzyme 2
Sequence:
MIQNEKKHLILYTGDVTKNLKSGIWNASRIKSNLELVKALENVKLTKFTGDGDENLKKNIKVLVPVNEKPQKLDGKQEEYEIIVKLFFLDGENIDIKKREETLSQVFYNLHMLFGIDFVSTLVVSFPHITFLKESGNSSSNEIYDSIDEIPPQEIQSWVDTWKLLEEKVGEGKIGTLGVSEFGVNELQRLISSVNVVPESTQINIGQNCKLPNDLLNFADRHHLKLFFHSDPSALLSESEITSVIHKACPEIPNPARVDWVIRYTILTRHTAVIHQKGYIVQSTYTE
Protein: Upstream transcription factor 2, c-fos interacting (M0R1C6)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRGRDGGTEKAKGSLCPPTPQAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDC
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit) (P34942)
Organism: Bos taurus (Bovine)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion matrix {ECO:0000305|PubMed:10852722, ECO:0000305|PubMed:18721790}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 5
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH-ubiquinone oxidoreductase chain 2
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 9
- Cytochrome b-c1 complex subunit 1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
Sequence:
MALRLLRLVPPRVGGIHTSVQFKLQYGPLAYILGEKATKKMTEKSKLITVDGNICSGKSKLAKEIAEKLGLKHFPEAGIHYVDSTTGDGKPLPVQFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTICEYLPPHVVVYVDVPVPEVQSRIQKKGNPHEMKITSAYLQDIENAYKGTFLPEMSEKCEVLQYSAWEAQDAEKVVEDIEYLKYDKGPWLDQNDRNLHKLRMLVQDKLEVLNYTSIPVFLPEVTVGAHQSDQVFQEFTELPGRKYRAGYNEDVGDKWIWLK
Protein: V-type proton ATPase 116 kDa subunit a 4 (V-ATPase 116 kDa isoform a 4) (V-type proton ATPase 116 kDa subunit a isoform 4) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform) (Q920R6)
Organism: Mus musculus (Mouse)
Function: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Involved in normal vectorial acid transport into the urine by the kidney (By similarity).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:11495928, ECO:0000269|PubMed:11498539}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:11495928, ECO:0000269|PubMed:11498539}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the apical surface of alpha-intercalated cells in the cortical collecting ducts of the distal nephron (PubMed:11495928, PubMed:11498539). Localizes to the basolateral surface of beta-intercalated cells in the cortical collecting ducts of the distal nephron (PubMed:11495928, PubMed:11498539). {ECO:0000269|PubMed:11495928, ECO:0000269|PubMed:11498539}.
Interaction partners:
- V-type proton ATPase subunit B, kidney isoform
- V-type proton ATPase subunit d 2
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase 16 kDa proteolipid subunit c
- V-type proton ATPase subunit d 1
- V-type proton ATPase subunit H
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase subunit S1
- V-type proton ATPase subunit F
- V-type proton ATPase subunit E 1
Sequence:
MASVFRSEEMCLSQVFLQVEAAYCCVAELGELGLVQFKDLNANVNSFQRKFVNEVRRCESLERILRFLEDEMQNEILIQVPEKDAETPLPREMITLETTLEKLEGELQEANQSHQALKKSFLELTELKYLLKKTQDFFETETNLGEDFFVEDTSGLLELRTIPAFMTGKLGFTAGVINRERMASFERLLWRVCRGNVYLKFSEMDTLLEDPVTKEEIKKNIFIIFYQGEQLRLKIKKICDGFRATIYPCPEHAAERREMLTSVNVRLEDLITVITQTESHRQRLLQEAAANWHSWVIKVQKMKAVYHVLNMCNIDVTQQCIIAEIWFPVADTRHIKKALEQGMELSGSSMIPIMTEVETKTDPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGMVMLMAALWMVLNERHLLAQKSTNEMWNIFFNGRYLILLMGIFSIYTGLIYNDCFSKSFNIFGSSWSVQPMFRNGTWNTHIVENSPYLQLDPAIPGVYSGNPYPFGIDPIWNLASNKLTFLNSYKMKMSVILGIAHMIFGVILSLFNHIYFRRTLNIILQFIPEMIFMLSLFGYLVFMIIFKWCRYDAHTSRKAPSILIHFIGMFLFDYDDSSNAPLYGHQQEVQTFFVIIALVSVPWMLLIKPFVLRAKHQKSQLQSFTIHEDAVEGDHSGHSSKKTAGAHGMKDGHEEEFNFGDIFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAELSEVLWTMVMSIGLRLQGWAGLVGVFIIFAVFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYEGAGSKFSPFSFKHVLEGTAEE
Protein: Peptidase M15B domain-containing protein (A0A0H2UP74)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVGSKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLIKAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFDVIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEIAASGLSLEEYYGFEGGDYVD
Protein: Debris buster, isoform G (MIP27980p) (F0JAR1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGLEKHYLRYGRTARDHLLDWATCGRGRRQQQQQQQQQTHAQPSQGSTATGRRSRPHVTHRGTPLSMLISNGVRISNSKYNTLNYIAKYASHPSEYK
Protein: Glutamate-gated chloride channel (DrosGluCl) (Q94900)
Organism: Drosophila melanogaster (Fruit fly)
Function: Glutamate-gated chloride channel subunit. Together with Gamma-aminobutyric acid receptor Rdl, plays an important role in the visual response by regulating the activity of ON/OFF-selective neurons.
Subcellular location: Postsynaptic cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit beta
Sequence:
MGSGHYFWAILYFASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKESMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSKRIDVISRITFPLVFALFNLVYWSTYLFREEEDE
Protein: Polyamine transporter RMV1 (Protein RESISTANT TO METHYL VIOLOGEN 1) (Q9FFL1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cell membrane polyamine/proton symporter involved in the polyamine uptake in cells. Possesses high affinity for spermine and spermidine and lower affinity for putrescine. Transports paraquat, a polyamine analog, and thus confers sensitivity to this chemical which is used as a herbicide.
Subcellular location: Cell membrane {ECO:0000305|PubMed:22492932}; Multi-pass membrane protein {ECO:0000305|PubMed:22492932}. Note=Plasma membrane.
Interaction partners:
- Cationic amino acid transporter 7
- E3 ubiquitin ligase PARAQUAT TOLERANCE 3
- Urea-proton symporter DUR3
- Phosphatidylinositol 4-phosphate 5-kinase 8
- Phosphatidylinositol 4-phosphate 5-kinase 7
- Putative phosphatidylinositol 4-phosphate 5-kinase 11
Sequence:
MTELSSPNLDSASQKPRISTENPPPPPPHISIGVTTGDPATSPARTVNQIKKITVLPLVFLIFYEVSGGPFGIEDSVKAAGPLLAIVGFIVFPFIWSIPEALITAEMGTMFPENGGYVVWVTLAMGPYWGFQQGWVKWLSGVIDNALYPILFLDYLKSGIPILGSGIPRVAAILVLTVALTYLNYRGLSIVGVAAVLLGVFSILPFVVMSFMSIPKLKPSRWLVVSKKMKGVNWSLYLNTLFWNLNYWDSVSTLTGEVENPSKTLPRALFYALLLVVFSYIFPVLTGTGAIALDQKLWTDGYFADIGKVIGGVWLGWWIQAAAATSNMGMFLAEMSSDSFQLLGMAERGMLPEVFAKRSRYRTPWVGILFSASGVIILSWLSFQEIVAAENLLYCFGMVLEFITFVRLRMKYPAASRPFKIPVGVLGSVLMCIPPTVLIGVIMAFTNLKVALVSLAAIVIGLVLQPCLKQVEKKGWLKFSTSSHLPNLME
Protein: O-acetylserine dependent cystathionine beta-synthase (EC 2.5.1.134) (O05393)
Organism: Bacillus subtilis (strain 168)
Function: Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine.
Interaction partners:
- Cystathionine gamma-lyase
- Uncharacterized methyltransferase YrrT
- Cystathionine beta-lyase MetC
- Cystathionine gamma-synthase/O-acetylhomoserine
- S-ribosylhomocysteine lyase
- Serine acetyltransferase
- 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
- Uncharacterized protein YrhC
- Cystathionine beta-lyase PatB
- Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase
Sequence:
MTVITDITELIGNTPLLRLKNFDVPEGVAVYAKLEMMNPGGSIKDRLGDMLIRDALDSGKVKPGGVIIEATAGNTGIGLALSARKYGLKAIFCVPEHFSREKQQIMQALGASIIHTPRQDGMQGAIQKAIQLETEIENSYCVLQFKNRVNPSTYYKTLGPEMWEALDGNIHTFVAGAGSGGTFAGTASFLKEKNPAVKTVIVEPVGSILNGGEPHAHKTEGIGMEFIPDYMDKSHFDEIYTVTDENAFRLVKEAAEKEGLLIGSSSGAALYAALEEAKKASAGTNIVTVFPDSSDRYISKQIYEGGI
Protein: Probable dual-specificity RNA methyltransferase RlmN (EC 2.1.1.192) (23S rRNA (adenine(2503)-C(2))-methyltransferase) (23S rRNA m2A2503 methyltransferase) (Ribosomal RNA large subunit methyltransferase N) (tRNA (adenine(37)-C(2))-methyltransferase) (tRNA m2A37 methyltransferase) (P9WH15)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01849}.
Interaction partners:
- tRNA
- Ribosomal RNA small subunit methyltransferase E
- Uncharacterized protein Rv2897c
- Putative methyltransferase Rv1407
- Ribosomal RNA small subunit methyltransferase H
- tRNA
- Ribonuclease J
- Phosphatidate cytidylyltransferase
- Ribosome-recycling factor
- tRNA-2-methylthio-N
Sequence:
MVPELMFDEPRPGRPPRHLADLDAAGRASAVAELGLPAFRAKQLAHQYYGRLIADPRQMTDLPAAVRDRIAGAMFPNLLTASADITCDAGQTRKTLWRAVDGTMFESVLMRYPRRNTVCISSQAGCGMACPFCATGQGGLTRNLSTAEILEQVRAGAAALRDDFGDRLSNVVFMGMGEPLANYARVLAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLHAPDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQPWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVRAKGVSCTVRDTRGREISAACGQLAAVGG
Protein: Zinc finger protein 589 (Stem cell zinc finger protein 1) (Q86UQ0)
Organism: Homo sapiens (Human)
Function: May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor.
Subcellular location: Nucleus {ECO:0000269|PubMed:23665872}.
Interaction partners:
- Transcription intermediary factor 1-beta
Sequence:
MWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNPCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGGNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKSSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGEKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYVCRD
Protein: Mitochondrial import receptor subunit TOM22 homolog (rTOM22) (Translocase of outer membrane 22 kDa subunit homolog) (Q75Q41)
Organism: Rattus norvegicus (Rat)
Function: Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
Subcellular location: Mitochondrion outer membrane; Single-pass membrane protein.
Interaction partners:
- Mitochondrial import receptor subunit TOM70
- Mitochondrial import receptor subunit TOM40 homolog
- Mitochondrial import receptor subunit TOM7 homolog
- Mitochondrial import receptor subunit TOM20 homolog
- Translocase of outer mitochondrial membrane 5
- Translocase of outer mitochondrial membrane 6.
- Mitochondrial import receptor subunit TOM40B
- Sorting and assembly machinery component 50 homolog
- Mitochondrial import inner membrane translocase subunit Tim21
- Metaxin-1
Sequence:
MAAAVAAAGAGEPLSPEELVPKAEAEKAEEDLEEDDDDELDETLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLPGKI
Protein: Rgt1p (A0A1D8PLL4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Transcription regulator
- SCF ubiquitin ligase complex subunit
- Glucose sensor
Sequence:
MTTTTIANQIPSINTMLSNVNNNNTPSANSSQSTLINQEQQQAQQQAQQQAQQSQHHRQHQSRSGGTTTNNNYSSSSDPPRKRSKVSRACDPCRKKKIKCNAEYSELEKKVTKICTSCAKNKEICTFDRTPLKRGPSKGYIRDLEEKAGDRISSLSSKSNQASTKANIPFPPSHQYPPPPQQQQKQQSPSIAIIPPNPYPPSNIQQLPFPQNSTTHRVTGSISNTPNNNNNNNNINNGNSPTIKLPPIVNYPSKSLPSPSLSKFNSSISSSQTSNPSSPKSQLSNIPGLLNNDSNTNNNVGGGGGGGGSEQTNSPPIQGPFWKVPYEMPQSSLSRRSSIGSITSTNGGQPNILRRPSVESISSVSTNGSRLPSIRPSISNDYTSDAESEDFYSVQSFRPRSLSRNSQSLSPRNSISSMSSLNGRINRSLAFNSSSVTSPIMIGSPSQQAQVQQQQSQSQLQLQQPPPPPPSSNMTNFMPPQVPIFAPFATTNHIPLNPLDLNLKLYYERFHTIFPILPYDSRIIYNILNDKSQPPWDWLIEVFNHSLNNLINFQQVELQSSIGIFIRLIQSYPFPNETTTTTITDNSLILFFSSLIILSYTNLINGDQYNAGISFTSSVFNDYKICERFIDQITNNKKDNDINVDVNVDVDNIVNYFTKLYYCLNLIDNLNSLTLGTNKNLHSQRIIKFLNHHKKKFLQINNNNNNNNNNNNSILNDCEIFDQLVEMRDKFITIDNTNYQGDDDVNEIINIDLINFNESKSSIHNNTNSNNNNNDDQFLKYFHQLIIDKYKIFKIILQFTKTNTSTSSSTTTTINGTTISNISNNGNNNSIEINSFNQELFNLIKSSNDNILNFANYISTTNNNNNNTSPKTSNSNSNSNFSYLIINNNPILNLSICQLFKSIKLHKLIIDKLPPPTTTTKTTISNDLDIDIDRLNNQLSISFNLLNLNLQNLKIGNMINQILQNKFNQLYKFQFNKSTDNNDIVDVDVDVDDIDMDMDIYKLNQWYDELNHVIVPFIIQDFKDGWI
Protein: Zinc transporter 3 (ZRT/IRT-like protein 3) (Q9SLG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates zinc uptake from the rhizosphere. May also transport other divalent cations.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative zinc transporter At3g08650
- IAA-alanine resistance protein 1
- Protein yippee-like At4g27740
- HSR201-like protein
- TPR repeat-containing protein ZIP4
- Heavy metal-associated isoprenylated plant protein 2
- Zinc transporter ZTP29
- Probable serine/threonine-protein kinase PBL15
- Metal tolerance protein A2
- Subtilisin-like protease SBT4.12
Sequence:
MKTKNVKLLFFFFSVSLLLIAVVNAAEGHSHGGPKCECSHEDDHENKAGARKYKIAAIPTVLIAGIIGVLFPLLGKVFPSLRPETCFFFVTKAFAAGVILATGFMHVLPEAYEMLNSPCLTSEAWEFPFTGFIAMIAAILTLSVDTFATSSFYKSHCKASKRVSDGETGESSVDSEKVQILRTRVIAQVLELGIIVHSVVIGISLGASQSPDAAKALFIALMFHQCFEGLGLGGCIAQGKFKCLSVTIMSTFFAITTPIGIVVGMGIANSYDESSPTALIVQGVLNAASAGILIYMSLVDLLAADFTHPKMQSNTGLQIMAHIALLLGAGLMSLLAKWA
Protein: Probable galacturonosyltransferase-like 2 (EC 2.4.1.-) (Q9S7G2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in pectin and/or xylans biosynthesis in cell walls.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Alpha-
- Probable xyloglucan glycosyltransferase 5
- Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein
Sequence:
MHSKFILYLSILAVFTVSFAGGERFKEAPKFFNSPECLTIENDEDFVCSDKAIHVAMTLDTAYLRGSMAVILSVLQHSSCPQNIVFHFVTSKQSHRLQNYVVASFPYLKFRIYPYDVAAISGLISTSIRSALDSPLNYARNYLADILPTCLSRVVYLDSDLILVDDISKLFSTHIPTDVVLAAPEYCNANFTTYFTPTFWSNPSLSITLSLNRRATPCYFNTGVMVIELKKWREGDYTRKIIEWMELQKRIRIYELGSLPPFLLVFAGNIAPVDHRWNQHGLGGDNFRGLCRDLHPGPVSLLHWSGKGKPWVRLDDGRPCPLDALWVPYDLLESRFDLIES