wanglab/gogpt-training-data huggingface dataset:
Protein: Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) (Q2MJB4)
Organism: Xenopus laevis (African clawed frog)
Function: May be involved in sexual development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
Interaction partners:
Sequence:
MELNGPPSSQVPHTPTCAPSLPITVAGTLLRGPQLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGILPPRPAYEVFGSLCGEGGTDSKIQKFDLFPKSLIPRSMTPQLPSGGKPGSPDSEPVSGSAPGASSPEAQPGSGSENGDGESLLSSPISKELKEGEESPSLISPLSSESGSDAEKDEQDPSSSSLARQRTPINILTRVFPAQKRSVLELVLQGCGGDVVQAIEQILNNRSQDKGEGTWSKDGALQSIQPSVSSTHRPLIAGALTPAIGTIGSRSAFSPLQPNAAHFGTEANTYQLGGHIGLNPLRLAYSAHSRGLAFMAPYSTAGFMPTLGFRPPMDYAFSDLMRDRANVHKDQVYTNGLYGPVVNNNAEKQ
Protein: N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (X-Pro-Lys N-terminal protein methyltransferase 1A) (S4R338)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVDITEDFLVQAKTYLGEEGKRVRNYFCCGLQDFTPEPDSYDVIWIQWVIGHLTDQHLAEFLRRCKGSLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLDVVRRIICSAGLSLLAEERQENLPDEIYHVYSFALR
Protein: Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4) (P19357)
Organism: Rattus norvegicus (Rat)
Function: Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
Subcellular location: Cell membrane {ECO:0000269|PubMed:2211693}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P14142}. Endomembrane system {ECO:0000269|PubMed:26240143}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P14142}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P14142}. Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized (By similarity). The dileucine internalization motif is critical for intracellular sequestration (By similarity). Insulin stimulation induces translocation to the cell membrane (PubMed:2211693). {ECO:0000250|UniProtKB:P14142, ECO:0000250|UniProtKB:P14672, ECO:0000269|PubMed:2211693}.
Interaction partners:
- Ras-related protein Rab-10
- Ras-related protein Rab-8A
- Ras-related protein Rab-14
- Insulin-2
- Insulin-1
- Ras-related protein Rab-2A
- Solute carrier family 2, facilitated glucose transporter member 1
- Ras-related protein Rab-11B
- Insulin receptor substrate 1
- Hexokinase-2
Sequence:
MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNATWLGRQGPGGPDSIPQGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLANNVLAVLGGALMGLANAAASYEILILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILVAQVLGLESMLGTATLWPLLLAITVLPALLQLLLLPFCPESPRYLYIIRNLEGPARKSLKRLTGWADVSDALAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFELAGVEQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPSMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTCNFIVGMGFQYVADAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISATFRRTPSLLEQEVKPSTELEYLGPDEND
Protein: sn-1-specific diacylglycerol lipase (EC 3.1.1.116) (Q8MR12)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MPGLVVFRRRWSVGSDDLVVPGAFLLTIHFICFVIVSVSLVIFEYNTRILSVKLLFYHLIGYLLILFFSICVEIGICVISMRGSILDAEARTSINIWIYLKSLVILFDIAWLAVGSVWLGHYYTTAPIDDPKKVYIAIIICNWALVVITLITIWCTFDAAGRSWVKMKKYQRSMRETESRFNYKRSNSMNRNWRQRKVMRAYQDSWDHRCRLLFCCMGSSERNRNSFTDIARLLSDFFRELDVVPSDVVAGLVLLRKFQRLEREAIVRQRKNGTYEFLSGVPITERTQFLALNDAKNYDFFQTVIHYMYFAQGAYGWPMYVIINRSKMWHLVPELKCFGCCCGTSDDTEVIQDNCCLCNYAALKKTLQLGDIDIVYATYHVDVGETPFFVAIDYTHRAVVISIRGTLSMKDILTDLNAEGEVLPLQPPRDDWLGHKGMVQAAIYIRNKLQEENLIERALQRNPDRQTHTFDLVLVGHSLGAGTAAILAILLKPEHPTLQCFSYSPPGGLLSMPAVEYSKSFITSVVLGKDVVPRIGLNQMEALRADLINAIQRSVDPKWKTISCSVICCGCGPEPTSVVNMSGQDTHINQYQEERGTARSTSAHPTDSSIALTLHQPLYPPGRIIHIVRHHPKPDEQKYDSGWR
Protein: Glutathione hydrolase proenzyme (EC 3.4.19.13) (CIK1 suppressor protein 2) (Extracellular mutant protein 38) (Gamma-glutamyltransferase) (EC 2.3.2.2) (Gamma-glutamyltranspeptidase) (Gamma-GT) [Cleaved into: Glutathione hydrolase heavy chain; Glutathione hydrolase light chain] (Q05902)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides. Major GSH-degrading enzyme, catalyzing the hydrolytic release of L-glutamate from GSH. Plays a role in the turnover of the vacuolar GSH, serving as an alternative nitrogen source during nitrogen starvation.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:11672438, ECO:0000269|PubMed:6143552, ECO:0000269|PubMed:6143574}; Single-pass type II membrane protein {ECO:0000269|PubMed:11672438, ECO:0000269|PubMed:6143552, ECO:0000269|PubMed:6143574}.
Interaction partners:
- Glutathione synthetase GSH2
- Cys-Gly metallodipeptidase DUG1
- Glutamate--cysteine ligase
- Glutathione reductase
- Transcriptional regulator URE2
- Glutathione-specific gamma-glutamylcyclotransferase
- Glutathione S-transferase 1
- Inactive alanine aminotransferase
- Alanine aminotransferase, mitochondrial
- Peroxiredoxin PRX1, mitochondrial
Sequence:
MLLCNRKVPKTLNTCFILHIFTLLTLGVLVSGMPSKMVSFASQETLQRINNLLRGSANRDVDIIAEYLKKDDDDDGGDKDHHNIDIDPLPRRPSLTPDRQLLKVGLHGAISSDLEVCSNLTINEVLLKFPGSNAADAAVTQALCKGMVNFFNSGIGGGGYVVFSGKDDEDHLSIDFREKAPMDSHKFMFENCSLCSKIGGLAVGVPGELMGLYRLFKERGSGQVDWRDLIEPVAKLGSVGWQIGEALGATLELYEDVFLTLKEDWSFVLNSTHDGVLKEGDWIKRPALSNMLMELAKNGSVAPFYDPDHWIAKSMIDTVAKYNGIMNLQDVSSYDVHVTKPLSMKIRKGANFIPDNDMTVLTSSGSSSGAALLAALRIMDNFQNQEGGDYEKETTYHLLESMKWMASARSRLGDFEGEALPKHIEEVLDPEWALKAVKSIKRNSQDGNFKTLENWTLYDPAYDINNPHGTAHFSIVDSHGNAVSLTTTINLLFGSLVHDPKTGVIFNNEMDDFAQFNKSNSFELAPSIYNFPEPGKRPLSSTAPTIVLSELGIPDLVVGASGGSRITTSVLQTIVRTYWYNMPILETIAYPRIHHQLLPDRIELESFPMIGKAVLSTLKEMGYTMKEVFPKSVVNAIRNVRGEWHAVSDYWRKRGISSVY
Protein: BOS complex subunit NOMO1 (Nodal modulator) (X1WEJ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
Interaction partners:
- BOS complex subunit TMEM147
- BOS complex subunit ncln
- Signal peptide peptidase 3
Sequence:
MGGIKELAILTLSFLYFTFVNATDDILVGCGGFVKSDVEINYSVIEIKLYTKQGSLKYQTDCAPINGYFMIPLYDKGDFVLKIEPPSGWSFEPTTVDLHVDGVTDICTKEQDINFVFTGFSVLGTVLSKGHLLGPAGVEVSLRKAGEDAVLQSVFTHAGGQYTFLKVLPGSYDITASHSSWTLEQSSTAVVVSNENAPAAAPLVVKGYDVSGEVQSDSEPMKGVSFLLYSASVTKEDISGCAVAPVDGALVGDASLVYLCSSQSREDGTFSFPCLPSGEYTVVPYYRGERITFDVAPSRMDFKVEHSSLTLQPVFRVMGFSVMGRVLNGPDGEGVADAVVTLNNQIKVETKEDGSFRLENMTTGTYTINTHKELMFFEPVTVKIAPSTPQLPDIITAGFSVCGHISVTRLPETVKQLGRYKVTLSAQRQDQGFFRTVESDSHGAFCFQVKPGDYSVQVTLPESEVKAGLALQPHSLDISLVDRPVTDLLFTQFIASVSGSVSCLVACGDLTVSLQPVSRQGERQNFQLSGSSETLTFTFGNVLPGKYKVSITQEEWCWKHKSVEIDVLDSYVEGVEFRQTGYLLRCSLSHAITLEFFQDGSLPENVGVYNLSKGVNRFCLSKPGVYKVTPRSCHQFEQDYYTYNTSAPSILTLTAVRHHMTGLITTDKMLDVTVTIKSSIESEPALVLGPLRSNEEQRREQQLLEIAARKKERGEAGDEKSPPVEEKPEELREPFHYEFSYWARAGEKITVTPSSKEFLFYPPEVEATITGENCPGRLVEITGRAGLFLTGQVAPTLEGVEITIKESKATTPLITVLTDENGAYSVGPLHSDSQYDISASKEGFVLTPVEGKTGDFKAFALAGVTFEIKAEDGVPLSGVLLSLSGASFRSNLLTQDTGLLTFNNLSPGQYYFKPMMKEFRFEPSAQMITVEEGQVLHIPITGFKTAYSCYGTVQSIGGDAEQGVAVEAVGQSECGMYSEDTVTDEEGRFRLRGLRPGCNYNIQLRGEGNDHIERALPPHKTIEVGNTDIDGINIIAFRQINQFDLSGNVITSPEHLPTLWVKLYKSDNLDNPFQSVSLGQSLFFHFQPLPRDGESYVLMLDTSLSRSQYDFKLPQVSFTSSGYHKHVTLTFNPKRKIPDQDVAQGSFIALPLTLLLLLAVYNHERVIPLLLQLVSQIQGVRGLAQASGDGLPVDEAKRPSKRPKTRRT
Protein: Double hit, isoform C (A0A0B4LFL6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSCTVSELPSGCRLRGMTASSQQSAANNSGNNGNGNGNGGGGGVVGGGGSLGGVSPTVGGSVGILGSTSNVLQESNATTFQRPQSQKPCCFCWCCCCSCSCLAIKNADENAPTKRDLVNAEFLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNSQKFKTLAQLQDNSNAGSKADSPT
Protein: Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2) (Q8TED4)
Organism: Homo sapiens (Human)
Function: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21949678}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MRSSLAPGVWFFRAFSRDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIWVNGQWGLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAENQDNPEDPGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNVFYMLISADVLACLLLCRLVYKEILAWKVSLSRGSGYKEI
Protein: Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3) (Q9R0A5)
Organism: Mus musculus (Mouse)
Function: Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19509051}. Cell projection, axon {ECO:0000269|PubMed:19509051}.
Interaction partners:
Sequence:
MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLKSDTQTSRKEAVLLAKMKHPNIVAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQKGKLFPEDTILNWFIQICLGVNHIHKRRVLHRDIKSKNVFLTHNGKVKLGDFGSARLLSSPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCALKHPFQANSWKNLILKICQGPIHPLPALYSCKLQGLVKQMLKRNPSHRPSATTLLCRGSLAPLVPKCLPPQIIREYGEQILDEIKISTPKNMKKQDSNRVRRALGEANSASMQEEERGRKCSHTELESTGTTPAGNALERAARGNPESGNPQEHGRHTSPASPHRPWWERHGPSSNVEALEKASILTSSFTAEDDRGGSVIKYEENARRQWVREPPEALLSMLKDADLSQAFQTYTIYRPGAEGFLKGPLSEDTASDSVDGDLDSVMLDPERFEPRLDEEDTDFEEDNENPDWVSELKKHVGYGDGPGGQLLGERA
Protein: Mitochondrial inner membrane protein oxa1-1 (Cytochrome oxidase biogenesis protein 1-1) (Sp1) (O14300)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Not essential for viability, while oxa102 is essential. When both genes are deleted the cell is non-viable, suggesting that oxa101 act as a back-up for oxa102.
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial inner membrane protein oxa1-2
- Cytochrome c oxidase subunit 2
- Tryptophan synthase
Sequence:
MLHFLIRPSTRCAGSPHFNSTSSFLRKRLQSKTILSKRLGFQFRPSSTNVLAEVSTATSGFNPSWWPYALIQNTAYTINVYAGAPWWVSIILTTLGVRLALTPVMIASFRNSTKLSVIQPEMKKELEAIKTAKLDNDQLALNQHSIALRGIYLKHNVNPFAIFILPLTQSAVFFSFFYAIRKMSRLSVDGFTTGGLAWFKDLSIPDPYCILPIINAGLMFSGMQMNRANTASTIGNSTNWRTFFFLCCLLSPLLTAKLPAAIFMYWIPSSLFNIVQGYILKNPVVRSKLGFAPLPSIIEKQPSGFTLITNPIKSLKEFYKGVRDGFKTQYEQLQKDVSRRAVATTSASTIRPNSHYKKLKELNRSKKNSKKQSN
Protein: Uncharacterized protein (Q387K6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDAYQSLSGRVASMEELLRRSESTMAMVLQRVKGIEEFVVASEGRHRNEGATRSDGLALKLDRVADACNVRLETVNNDLQRQGATVRLLEESVKSIASTVEQKVNCDILACYQRLQTVETSLTSSVRNLESGIKSQLDCLRSTDQTIQGELASVQHTFSGELLQTRQRVEKLEASVRSALDELRGMFSNEVVKLSDSFKMQLQSYNQSSSAALAALDQKLQDGLNTLQGTLAREISADRQTISSVDTNLRDGLQSLHSTVNTDIATLSARLQSEEVASRAMQQQLLTELSSHRQQLETVDTNWRASLTDLAGKLQDECQGLRGKQSVVETTLQRSLGQVNARVEEVAGELHRTTDNIERNVQTRLASIEGIRDDISRIKCSLATEQDERRRLQEELRSFSVLAERSVMQLQSVMEATVRATHSDLLERLRPLTTYRSEMHAAVTAALNKLWCEVRETFTSQREFQAIQNQIEVLDNAVRKEVALLAEKGRLLERRTEKQSAGTVSTELARVSTESSALVPFDAAGELNTVWTELRDLQKRLGTSKEEMIALIGHTRKELLNSTLDIVKDSSDEFRGALTDIKTDVQLLMPRVEKALTAARAAVEKNAGKDGAGNPKKTVIRLLRKSLDDPTKCGENAVYVLPAESEAPLHSFTKERGREGPYGKKNTAPNDDTMTSGAANRPLPEKMQTNPRAPVEHNMEGNGLSKGRPVVPALSERALQISAAREEPTRSPLVSQKDYKGYAANAGEHIASAGVPHATTVRRGSPNATASGERELDGQMRGSRPSHGFADVDTVSASLLPPLVRGARASPSPGPYPVTSK
Protein: Elongation factor 1-alpha (C0HAL2)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETGRYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAGGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRFEEIQKEVTTYIKKIGYNPATVAFVPISGWHGDNMLEASANMGWFKGWKVERKDGNANGVTLLEALDSILPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGTLKAGMIVTFAPANVTTEVKSVEMHHETLESAMPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPMEAGTFTAQVIILNHPGQISQGYAPVLDCHTAHIACKFSELKEKIDRRSGKKLEDAPKFLKSGDAAIVDMIPGKPMCVESFQEYPPLGRFAVRDMRQTVAVGVIKAVDKKAASSGKVTKSAVKAGKK
Protein: glycerol kinase (EC 2.7.1.30) (Q8IGQ5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAIVNTVNECITGACKKLVAVGGKVEEIITIGITNQRESTVVWDRNSGQPLVNAIIWLDNRTTSTVEELLETIPNNARNINYLRPLCGLPLSPYFSGVKLRWLRDNVPVVSQAMEKGTAMFGTIDTWLMYNLTGGKDCGVHKTDVTNASRTMLMNIETLQWDANLLKFFGLPKTILPEICSSSEFYGSIAQGVLQGIGITSVLGDQQAALVGQQCLAKGQAKATYGTGCFLLYNTGPSIVHSTHGLLTTVGYQLGRKAVPFYALEGSVSIAGAAFNWLRDNMNLIQNSGQVETMASTVDNSLDVYFVPAFNGLYAPYWNQDARGVICGLSEETTSEHIVRATLEAVCFQVRDILDSMHKDCKIPLAKLMVDGGMTVNNLFLQLQSDLVGIQVLRAKIAETTALGAAMAAYKAVENRYQMEAPLSKSGPREAIKPSISATDRNLRYQKWKMAIDRSLNWETSTLPQGEREAFDGA
Protein: Meiotic expression up-regulated protein 31 (Q9Y826)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Meiotically up-regulated gene 126 protein
- Putative uncharacterized transmembrane protein C1235.18
- Protein pdh1
- Pterin-4-alpha-carbinolamine dehydratase
Sequence:
MSCISEIGKFVKSIEYIKLPCLFIFAAIVGMNLSLLYCLLKGWKNVMIWGIETMLFGAIGIFFAWKKKLSWEHLVLLWSTIDAFFSMCLRSCTIIYFSMNPYMLCEILNARNVISCSLNTQKFFFIIVAASNVYSIFQLCGCLLMFNNIISIRPSERTEPEFNFDLEKGVAFASDSEFPEKSICI
Protein: Carnitine monooxygenase oxygenase subunit (EC 1.14.13.239) (Carnitine monooxygenase alpha subunit) (P0ABR7)
Organism: Escherichia coli (strain K12)
Function: Converts carnitine to trimethylamine and malic semialdehyde. Can also use gamma-butyrobetaine, choline and betaine as substrates.
Interaction partners:
- Carnitine monooxygenase reductase subunit
- 3-phenylpropionate/cinnamic acid dioxygenase subunit beta
- NADH oxidoreductase HCR
- Uncharacterized transporter YeaV
- PF03932 family protein CutC
- 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit
Sequence:
MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFAKSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGKAKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPNATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPGFSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPIKGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQKGLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD
Protein: Chaperone ATPase (A0A1D8PTP9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Heat shock protein 78
- Eukaryotic peptide chain release factor GTP-binding subunit
- Hsp90 cochaperone
- Heat shock protein HSP70
- Type II HSP40 co-chaperone
- Heat shock protein 90 homolog
- Heat shock protein SSA2
- Small heat shock protein 21
- Type I HSP40 co-chaperone
- PI31 proteasome regulator C-terminal domain-containing protein
Sequence:
MEDFTDNAIKIINNATELAKQQANSQLLPLHFLAAFIPSDDTEGSTQYLKTLVKRARYEWGDFERIVNRHLVKIPSQNPPPDEIRPSYQAGQVLTKANKIKQQQKDSYVAQDHILLALLEDQSIKDIFKEAGMSVDTIKTQAIELRGSQRIDSRQADSSSSYEFLNKYCEDFTEKAREGKIDPVIGREEEIRRVIRVLARRSKSNSVLIGDAGVGKTSIVEGVAQRIVDGDVPNVLAGSRLFALDLGALTAGAKYKGEFEERLKGVLNEIEKSKEFIILFIDEIHMLMGDGKSDAANLLKPMLARGALHCIGATTFAEYRKFISKDGAFERRFQKIDVPAATVQETVAILRGIQPKYEIHHGVRILDSALVTAAQLASRYLTYRALPDSAVDLVDESAAAVAVARDSKPEELDTLERQLHLVDVEINALERDKDADSASKERLNLAKKKKAELEEKIGPLNERYRQERASHEQLTAAKRKLDELEIKAQDAERRYDTATAADLRYFAIPDIQKQIEELEVKVVEEEASNLDSLLKNAVGPEQICETAARLTGIPVTKLSQAENNKLINMEAELSKEVVGQSEAVKAVSNAIRLRRSGLANPNQPPSFLFLGLSGSGKTELAKKLAGFLFADEKAIIRIDCSELGDKWSASKLLGAAPGYVGYEEGGILTEPLIRRPYSVVLLDEVEKAAPEVLTVLLQILDDGRVTSSQGKLVNCSNAIFIMTSNLGANYINAAKGSKIDANTKEHVMDAVRAHFRPEFINRISSIVVFNRLSRKAISKIVKIRLSEIENRFTANGKAIQLKLDDDAMEYLCKNGWSPDLGARPLNRLIQNEILNRLAVMLLKGQIQDKETARVVLGEKGLEILPNHEPEDVEMNDVDNWQDSEDEDDDEARFTSPGLD
Protein: Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase) (Q5B912)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Involved in osmoadaptation.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Plasma membrane ATPase
- Plasma membrane ATPase
- inorganic diphosphatase
- ATP synthase subunit 5
- V-ATPase proteolipid subunit Ppa1, putative
- ATP synthase subunit gamma
- ATP synthase subunit alpha
- ATP synthase subunit alpha
- Vacuolar ATP synthase subunit D, putative
- V-type proton ATPase proteolipid subunit
Sequence:
MSYTVRKIGQPYTLEHRVYIEKDGQPVSPFHDIPLYANAEKTVLNMIVEIPRWTNAKQEISKEEFLNPIKQDTKKGKLRFVRNCFPHKGYLWNYGAFPQTWEDPNVVHPETKAKGDNDPLDVCEIGELVGYPGQVKQVKVLGVMALLDEEETDWKVIVIDVNDPLAPKLNDIEDVERHLPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYAEEVIHECADAWEKLVSGKSDRGDISLANSTLGNSDSVDSSKLASIPRGENLPPAPIDGTIDKWFFISGAAV
Protein: Epididymis secretory sperm binding protein Li 44a (Serpin peptidase inhibitor clade A member 1 isoform 1) (E9KL23)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQK
Protein: Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS) (P12081)
Organism: Homo sapiens (Human)
Function: Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:F1Q5D5}.
Interaction partners:
- Glycine--tRNA ligase
- Histidine--tRNA ligase, mitochondrial
- Tyrosine--tRNA ligase, cytoplasmic
- Alanine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase
- Methionine--tRNA ligase, cytoplasmic
- Threonine--tRNA ligase, mitochondrial
- Threonine--tRNA ligase 2, cytoplasmic
- Asparaginyl-tRNA synthetase
- Serine--tRNA ligase, cytoplasmic
Sequence:
MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC
Protein: Flavonoid 3'-O-methyltransferase FOMT (EC 2.1.1.-) (Q42654)
Organism: Chrysosplenium americanum (American golden saxifrage)
Function: Catalyzes the 3'- or 5'-O-methylation of partially methylated flavonols, but does not accept quercetin or caffeate as substrates for methylation.
Interaction partners:
Sequence:
MLFAMQLASASVLPMVLKSAIELDLLEIIASQDTCMSPTEIASHLPTTNPHAPTMIDRILRLLSSYSIVTCSVRSVDDQRVYSPAPVCKYLTKNQDGVSIAALCVAAQDKVLMECWYHMKDAVLDGGIPFNKAYGMPIFDYFAKDLGSNKVFNKGMSDFSSMIIKKILETYKGFQGLTSLVDVGGGTGATLTKILSKYPTIRGINFDLPHVIQDAPEYPGIEHVGGDMFVSVPKGDAIFMKWICHDWNEEQCLKLLKNCYDALPNNGKVIVAEYILPVVPDSSLASKLSVTADVMIVTQNSGGKERTEKEFEALAKAAGFQGFQVFCNAFTIYIIEFSKNISN
Protein: Transmembrane protein 203 (Q8R235)
Organism: Mus musculus (Mouse)
Function: Involved in the regulation of cellular calcium homeotasis. Required for spermatogenesis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:31346090}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:31346090}. Lysosome membrane {ECO:0000269|PubMed:31346090}; Multi-pass membrane protein {ECO:0000255}. Note=Co-localizes with STING1 in the lysosome membrane, mediates lysosomal localization of STING1. {ECO:0000269|PubMed:31346090}.
Interaction partners:
Sequence:
MLFSLRELVQWLGFATFEIFVHLLALLVFSVLLALRVDGLTPGLSWWNVFVPFFAADGLSTYFTTIVSVRLFQDGEKRLAVLRLFWVLTVLSLKFVFEMLLCQKLVEQTRELWFGLITSPVFILLQLLMIRACRVN
Protein: Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHX-AP1) (PAHXAP1) (Q92561)
Organism: Homo sapiens (Human)
Function: Its interaction with PHYH suggests a role in the development of the central system.
Interaction partners:
- Phytanoyl-CoA dioxygenase, peroxisomal
Sequence:
MELLSTPHSIEINNITCDSFRISWAMEDSDLERVTHYFIDLNKKENKNSNKFKHRDVPTKLVAKAVPLPMTVRGHWFLSPRTEYSVAVQTAVKQSDGEYLVSGWSETVEFCTGDYAKEHLAQLQEKAEQIAGRMLRFSVFYRNHHKEYFQHARTHCGNMLQPYLKDNSGSHGSPTSGMLHGVFFSCNTEFNTGQPPQDSPYGRWRFQIPAQRLFNPSTNLYFADFYCMYTAYHYAILVLAPKGSLGDRFCRDRLPLLDIACNKFLTCSVEDGELVFRHAQDLILEIIYTEPVDLSLGTLGEISGHQLMSLSTADAKKDPSCKTCNISVGR
Protein: Secreted transmembrane peptide 6 (Phytocytokine STMP6) (Precursor of secreted transmembrane peptide 6) (O04468)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (By similarity). Prevents general growth and development.
Subcellular location: Cell membrane {ECO:0000269|PubMed:31001913}. Secreted, extracellular space, apoplast {ECO:0000269|PubMed:31001913}. Note=The precursor of STMP6 accumulates at the plasma membrane and is proteolytically cleaved to release the STMP6 in the apoplasm. {ECO:0000269|PubMed:31001913}.
Interaction partners:
- AAA-ATPase At3g28600
- AT5g19120/T24G5_20
- Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic
- Ulp1 protease family protein
- DnaJ domain protein
- 1-aminocyclopropane-1-carboxylate oxidase 3
- Glycine--tRNA ligase, chloroplastic/mitochondrial 2
- At2g17880
Sequence:
MGMKSPNIAAFMLPLLLILFTLSSQLKVVESTGRKLAWGFSGTPIVYTPPSRSCGTSPAVFTSKWRRPRPCRLPPGSYIPASDQSP
Protein: Phenazine biosynthesis protein PhzB2 (Q9S508)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. PhzB2 (operon phzA2B2C2E2F2G2) has a role in the biosynthesis of the phenazine during both planktonic growth and biofilm development, and in host infection during biofilm development.
Interaction partners:
- Trans-2,3-dihydro-3-hydroxyanthranilate isomerase
- Probable pyridoxamine 5'-phosphate oxidase
- Phenazine biosynthesis protein PhzD1
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- anthranilate synthase
- 5-methylphenazine-1-carboxylate 1-monooxygenase
Sequence:
MLDNAIPQGFEDAVELRRKNRETVVKYMNTKGQDRLRRHELFVEDGCGGLWTTDTGSPIVIRGKDKLAEHAVWSLKCFPDWEWYNIKVFETDDPNHFWVECDGHGKILFPGYPEGYYENHFLHSFELDDGKIKRNREFMNVFQQLRALSIPVPQIKREGIPT
Protein: Glutamine-dependent asparagine synthetase (C9JT45)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVKKYPYLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGVFAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAK