wanglab/gogpt-training-data huggingface dataset:
Protein: Nucleoporin (NUP54/57), putative (Q584I6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nucleoporin NSP1-like C-terminal domain-containing protein
- Nuclear pore complex protein
- Nuclear pore protein
- Nucleoporin
- Uncharacterized protein
- Long-chain-fatty-acid-coA ligase protein,putative
- Nucleoporin
- Protein transport protein sec13, putative
- Protein transport protein Sec13, putative
- RanBD1 domain-containing protein
Sequence:
MSVLGSGFGRGAPGGFGAPACSTAGGFGSGFNTATTGGFGAGANTATTGGFGAGANTATTGGFGAGANTVTTGGFGAGANTATTGGFGAGANTVTTGGFGAGANTATTGGFGAGANTATTGGFGAGANTATTGGFGAGANTATTGGFGAGANTATTGGFGAGANTATTGGFGAGANTVTTGGFGAGANTATTGGFGAGANTATTGGFGAGANTVTTGGFGAGANTATTGGFGAGANTVTTGGFGAGANTATTGGFGAGANTATTGGFGAGANTATTGGFGAGANTATTGGFGAGANTVTTGGFGAGANTATTGGFGSGFNTAGGLGSGGFGAGPNTAGGFGTASVSFFGSTAAGAESRPNAVGASQQQVINCQSAVGRYLLEIDHAYNAMHPNCRFRSFLYNVCAPGQSIMAVERERLIYAAAGGECKEEDLLRAQQRNPDPVHLYPTRVHFMQELKNRVEKQKEILEAMSRHVDSLATKADHFRELDEANAAQYRELQQEQAMLQRRWYSLLMKVETLRQLGLPLAEESRMGGIASTLSAQLSAPGMYKTALTELQPFLDAESSTITSFLRRNSVGGSEGAICTPSEGVGTLRNNRVDQALLRDWARFAERIQQCVEGLSELLERDAADMRAIYQRVASS
Protein: Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)] (P15639)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Adenylosuccinate lyase
- Phosphoribosylamine--glycine ligase
- Phosphoribosylformylglycinamidine synthase
- Amidophosphoribosyltransferase
- Phosphoribosylglycinamide formyltransferase
- Phosphoribosylformylglycinamidine cyclo-ligase
- N5-carboxyaminoimidazole ribonucleotide mutase
- Serine hydroxymethyltransferase
- Formate-dependent phosphoribosylglycinamide formyltransferase
- N5-carboxyaminoimidazole ribonucleotide synthase
Sequence:
MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKLDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPSEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
Protein: Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1) (Q7L523)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:8995684, ECO:0000269|PubMed:9394008}. Nucleus {ECO:0000269|PubMed:8995684, ECO:0000269|PubMed:9394008}. Lysosome membrane {ECO:0000269|PubMed:20381137, ECO:0000269|PubMed:28935770, ECO:0000269|PubMed:29158492, ECO:0000269|PubMed:31036939}. Note=Predominantly cytoplasmic (PubMed:8995684, PubMed:9394008). Recruited to the lysosome surface by the Ragulator complex (PubMed:20381137, PubMed:28935770, PubMed:29158492). May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state (PubMed:8995684, PubMed:9394008). Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane (PubMed:8995684). {ECO:0000269|PubMed:20381137, ECO:0000269|PubMed:28935770, ECO:0000269|PubMed:29158492, ECO:0000269|PubMed:8995684, ECO:0000269|PubMed:9394008}.
Interaction partners:
- Ragulator complex protein LAMTOR1
- GATOR1 complex protein NPRL2
- Ras-related GTP-binding protein D
- Ragulator complex protein LAMTOR3
- Neutral amino acid transporter 9
- GATOR1 complex protein DEPDC5
- Ragulator complex protein LAMTOR5
- Ragulator complex protein LAMTOR4
- GATOR1 complex protein NPRL3
- Regulatory-associated protein of mTOR
Sequence:
MPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAQIIEADEVLLFERATFLVISHYQCKEQRDVHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKHSLLMR
Protein: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Q12552)
Organism: Aspergillus niger
Subcellular location: Cytoplasm.
Interaction partners:
Sequence:
MAPKVGINGFGRIGRIVFRNAINHGEVDVVAVNDPFIETHYAAYMLKYDSTHGQFKGTIETYEEGLIVNGKKIRFFAERDPAAIPWGTTGADYIVESTGVFTTQEKAAAHLKGGAKKVVISAPSADAPMFVMGVNNTSYTKDINVLSNASCTTNCLAPLAKVINDKFGIVEGLMTTVHSYTATQKVVDAPSSKDWRGGRTAAQNIIPSSTGAAKAVGKVIPTLNGKLTGMAMRVPTSNVSVVDLTCRLEKATSYDEIKKALKDASENELKGILGYTEDDIVSSDLNGDDHSSIFDAKAGIALNSNFVKLVSWYDNEWGYSRRVVDLIAYISKVDAQ
Protein: RNA end formation protein 2 (P42073)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Negative regulator of poly(A) synthesis. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation. REF2 is required for 3'-end formation of snoRNAs.
Subcellular location: Nucleus {ECO:0000269|PubMed:12819204}.
Interaction partners:
- Pre-mRNA polyadenylation factor FIP1
- Protein SYC1
- Cleavage factor two protein 2
- Endoribonuclease YSH1
- Protein CFT1
- Serine/threonine-protein phosphatase PP1-2
- mRNA 3'-end-processing protein RNA14
- mRNA 3'-end-processing protein YTH1
- Polyadenylation factor subunit 2
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
Sequence:
MSAPVPQLVNISHALQASTIQQIRLDMVDFNKDCKLSSIQLARIDKYIDSLQAALNQFTKDNLHIERKEKNVTEADIQLYSGLKSMYLDYLNQLIKLKHEKQHHSTPPIANDVSLDFFVNQLPKFSPEERKNYIDNLILNKNSHNRLSKMDGLVDAVINLCVLDTSVAENVRSYMKLLDTLGFQKGSNSTGTKANLKKKLASSKAKIKDSEKEKEKEKDKSKVKMKTKLKPSPLLNNDDKNSSPSPTASTSSMKKLKSGLFNKNEAKSTESLPTSSKKKLSFSKYLNKDDADMTKLGTKRSIDVDFKVNPEASTVASNIISSSTSGSSTTTVATPASSEEPLKKKTKISVQDSNVQSILRNGKPKKARISSIKFLDDSQLIKVYGDDLPNQGLQVSPTQLKKILKPFKEGEPKEIILFEDMSIKLKPLDLMFLKNTNSDDYMDISETKGGPIHCETRTPLIYRKNFNHFNPDLNKRPPREPIEFDLNGNTNSTPTIAKAFGKNSLLLRKDRGGLPYKHVPIVKRNKYPPRPVH
Protein: Nuclear pore complex protein NUP54 (Nucleoporin 54) (Q8GYF7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:21189294}. Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
Interaction partners:
- Protein SEH1
- Nuclear pore complex protein NUP35
- Nuclear pore complex protein NUP155
- Nuclear pore complex protein NUP107
- Nuclear pore complex protein NUP205
- Nuclear pore complex protein NUP93A
- Nuclear pore complex protein NUP85
- Nuclear pore complex protein NUP62
- Aladin
- Nuclear pore complex protein NUP88
Sequence:
MFGTPSSSPSFGTPSSTPAFGTSSPAFGTPSATPAFGTPSNPSFSSGGFGSSLFSSPFSSQQPQQQQQQQQQQQPSSLFQQQPSSNFGFQSPFNNTAQQQQQTPFPNAQLTTQMAPVAPIPYSLADRDVQAIIEAYKEDPTNPKYAFQHLLFSVTEPQYRVKPAAVSDIMWAEAMSKLEGMDSTERERLWPQLVQGFKDLSQRLKLQDEVLVSDRDRIKTTQSNVKMLQRHLQASTFPSIERLRQKEQSLQRRMLRVMRIIEGLEGKGFRLPLTKGEAELSEKLTAITRQVKGPGAELSRRVQSLQTISRAQANSIAAGSSLYLPGSTKIDEQSLIDMQEVLQQETEAIGRLGNVLKRDMRDMEIMVAEDTEMALDS
Protein: glutaminase (EC 3.5.1.2) (B7Z509)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNLDGLL
Protein: Styryl dye vacuolar localization protein 3 (Q03088)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May have a vacuolar function.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Bud {ECO:0000269|PubMed:14562095}. Bud neck {ECO:0000269|PubMed:14562095}. Cytoplasm, cell cortex {ECO:0000269|PubMed:14562095}. Note=And found in the cell periphery.
Interaction partners:
Sequence:
MSSSSLRVLAIGNNPNILFYTSRFQLAKNIDLYHVNDSKSCQFEIETEYYGKDRFELENHFTSIEHLTEALSSKSSEAVFDIIIMSAPSLQELSSLASKLTSIIDSNTKIFLESSGFIQLEPFVKLSMESPHVNVFSILTDLDIRQIGPNHFKHFPSTAKENTIYLGESKSSTEKYSSGVITLLTTFEKLFAKLFSNIKINLCNFSSIEFLSQQWKLAISRICFDPLLIMFEQENPSDLDQQIIAKPLISGLVTEIITVAKTMGARLNSSHDNENSLLSLWKNSYHSTNKPPALVYHFIHQTTPLNIDILLLQTILLADDFGIKTPYLEFLYSVLSQFERLNSGKSKWFIRSDEKTQILQSLQKSQKNESALQTQITSLQGQISKLRQELLMQAKQHEMETNELKEKHQVALKAQAQAQAQAQSQAQTSIEALTPTEATNQSDTNEYKATGTPNLRDIEDMALYSVNYGDSPVRSPPPVVSSQPQMNSPLSSHSQTFGENNGTNDKLLQERELQLRKKELELQERELEFQKRALQQQRFNNSNNSIPRKPSFPQLQQSANVRSNSRGMHGTNGAMSQPASAGNFVDPISSSIAAYDPQQPPSLPLQQPQQSVQVQPFHSHSIKPTSRKNRNSNMPNIGNPSSINMSDFGRPPNNSSQTRLNSMPTHSIVNQNRLRSQQSKNKLNMPHATNPNNTFNQVPAPSLNNHVPTQRQFSSSTMIEVTNNNNKVNNSSSNPDISTNSVVHNAMQFTNTNNNTSSTVDINDPKNIAPPPTTSVSAPSTPTLSSSSQMANMASPSTDNGDNEEKNGGKKKRFGLFKKKNKSKK
Protein: F9L1.8 protein (FAD/NAD(P)-binding oxidoreductase) (Q9XI55)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Dihydroorotate dehydrogenase
- Dihydropyrimidine dehydrogenase
- Uridine 5'-monophosphate synthase
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- Allantoinase
- Dihydropyrimidinase
- Carbamoyl phosphate synthase small chain, chloroplastic
- Carbamoyl phosphate synthase arginine-specific large chain, chloroplastic
- Aspartate carbamoyltransferase, chloroplastic
- Uncharacterized aarF domain-containing protein kinase At5g05200, chloroplastic
Sequence:
MSTLPFAPSVTHAHFSHSLSPMFILRHLPLTRHLRLSRNNRVASVVSAAAVRQDASLWTPAPLSLIESAAESLFHISIDISNAPDLVASYTRPGQYLQIRVPDVEKPSFMAIASPPSLASSRGAFEFLVKSIAGSTAEILCGLKKGETVELSSVMGNGFNIDLIDPPEEYPTVLIFATGSGISPIRSLIESGFGADRRSDVRLYYGARNLNRMAYQEKFKEWESAGVKVVPVLSQPDDGWKGETGYVQAAFARAKQLSAPKATGAVLCGQKQMAEEITSMLVADGVSNDKLLKNF
Protein: Auxin efflux carrier component 8 (AtPIN8) (Q9LFP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the intracellular auxin-transport pathway in the male gametophyte. Involved in the regulation of auxin homeostasis in pollen. Involved in the efflux of auxin from the endoplasmic reticulum into the cytoplasm. PIN5 and PIN8 may have an antagonistic/compensatory activity. Involved in the control of vein patterning. Redundantly with PIN6, inhibits the vein-formation-promoting functions of PIN5. PIN5, PIN6, and PIN8 control vein network geometry, but they are expressed in mutually exclusive domains of leaf vascular cells.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19506555, ECO:0000269|PubMed:20439545, ECO:0000269|PubMed:22540348, ECO:0000269|PubMed:22760640, ECO:0000269|PubMed:23437008}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:20439545}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes to endoplasmic reticulum in pollen, growing pollen tubes and leaves. {ECO:0000269|PubMed:22540348, ECO:0000269|PubMed:22760640}.
Interaction partners:
- Auxin transporter protein 1
- Protein PIN-LIKES 2
- Protein PIN-LIKES 5
- ABC transporter B family member 1
- Auxin transporter-like protein 3
- ABC transporter B family member 4
- ABC transporter B family member 19
- Protein WALLS ARE THIN 1
- Auxin transporter-like protein 2
- Auxin-binding protein 1
Sequence:
MISWLDIYHVVSATVPLYVSMTLGFLSARHLKLFSPEQCAGINKFVAKFSIPLLSFQIISENNPFKMSPKLILSDILQKFLVVVVLAMVLRFWHPTGGRGGKLGWVITGLSISVLPNTLILGMPILSAIYGDEAASILEQIVVLQSLIWYTILLFLFELNAARALPSSGASLEHTGNDQEEANIEDEPKEEEDEEEVAIVRTRSVGTMKILLKAWRKLIINPNTYATLIGIIWATLHFRLGWNLPEMIDKSIHLLSDGGLGMAMFSLGLFMASQSSIIACGTKMAIITMLLKFVLGPALMIASAYCIRLKSTLFKVAILQAALPQGVVPFVFAKEYNLHPEIISTGVIFGMLIALPTTLAYYFLLDL
Protein: FA complementation group L (B5MC31)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAVTEASLLRQCPLLLPQNRSKTVYEGFISAQGRDFHLRIVLPEDLQLKNARLLCSWQLRTILSGYHRIVQQRMQHSPDLMSFMMELKMLLEVALKNRQELYALPPPPQFYSSLIEEIGTLGWDKLVYADTCFSTIKLKAEDASGREHLITLKLKAKYPAESPDYFVDFPVPFCASWTPQSSLISIYSQFLAAIESLKAFWDVMDEIDEKTWVLEPEKPPRSATARRIALVVKPLGIKLSRNIHLWDPENSVLQNLKDVLEIDFPARAILEKSDFTMDCGICYAYQLDGTIPDQVCDNSQCGQPFHQICLYEWLRGLLTSRQSFNIIFGECPYCSKPITLKMSGRKH
Protein: Protein Star (P42519)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in EGF receptor signaling. Has an early role in photoreceptor development. Interacts with the receptor torpedo in the eye.
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein.
Interaction partners:
- Protein rhomboid
- Protein spitz
- Ras-like protein 1
- Epidermal growth factor receptor
Sequence:
MSQQVFSAHPALAVDQLQQAEQEEHNTSSNHHQQRSATQSRRHTKAAPKKFTLSRSCAGGGSGTLSGVHQQVKPSPSNPAISPECRKTLPVRTNYAAVDDDDDIECEDVDEVNFGQQEKERERETRQPTKDCGTDETDHVQQRHKNTMTTSATAASRHHHQDGGGGDQSDLSSVISSPSVSTVSSPLSTPTRLPQALQQQLHCCQKSTGMESRARTSPQQIQHPHRQHHQQQHHHHHHHHHLTAAGCTGGGGGGGGSGGSGSCKAKKLDPRLNPSPYRQLLPIALCLLSFAAVFATLIVYMDTTEIRHQQFRLNMSRDYELNGVAQDDPALIDFLRQIHMGKYLGKASPKVAAAASVGVGPPPNSPRLAAAGSTFGSGNSSGSGADQLAHYVADLVGGKMNGAVIQSLSGPLAHLITAPWLSEQLNWMGVLVEPEPRWYFTLRKQNAQRARMQVVHACVSPNTYPKEITIHNEDVRINSLHDEETSWFNSRVKCFPLYTIMLACERTEYDLLSLGVQGHELEILQTLPFDKVKIDVISIHLLEDHEDVADYVLDITRFLAGKSYKLQRKIGRNYFYQRLNASASRTRKKDILLLKTP
Protein: Zinc transporter ZIP1 (DrZIP1) (Solute carrier family 39 member 1) (Zrt- and Irt-like protein 1) (ZIP-1) (P59889)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Mediates zinc uptake.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9NY26}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9NY26}; Multi-pass membrane protein {ECO:0000255}. Note=Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines. {ECO:0000250|UniProtKB:Q9NY26}.
Interaction partners:
- Solute carrier family 30 member 1b
- Solute carrier family 30
- Zinc transporter ZIP10
- Zinc transporter Slc39a7
- Zinc transporter ZIP13
- Metal cation symporter ZIP14
- Solute carrier family 30
- Zinc transporter ZIP9
- Solute carrier family 39 member 6.
- Solute carrier family 39 member 8.
Sequence:
MDYLLQVKVGALVGLLLLTLFFGFIPARMKWFHVTGGTELHKAVLSFVSCFAGGVFLSACLLDIIPDYLSDIHGELQKRDLDDGFPLPEFIMACGFFTVLILEKMVLSCTEGHRNEETAPLLAPAAPNGHAHGHPSVNDLEGSGHHVHVDFHAHSSFRSFMLFLSLSLHSVFEGLAIGLQTTNAKVLEICIAILVHKSIIVFSLSVKLVQSAVKPLWVVLYVTVFAIMSPLGIGIGIVVIETERQAGGLIQAVLEGLAAGTFIYITFLEILPHELNSSERPLLKVLFLLCGFSIMAALCFLG
Protein: Nuclear pore complex protein Nup98-Nup96 (E7F981)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus membrane {ECO:0000256|ARBA:ARBA00004620}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004620}; Nucleoplasmic side {ECO:0000256|ARBA:ARBA00004620}. Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
- mRNA export factor
- Nucleoporin 155.
- Nucleoporin 214.
- Nuclear pore complex protein
- Nuclear pore complex protein Nup133
- Protein SEC13 homolog
- Nucleoporin SEH1
- Nuclear pore complex protein Nup93
- Nucleoporin 160.
- Nucleoporin 37.
Sequence:
MFNKSFGAPFGGGTGGFGTSSTFGQPNSGFGATPGGFGSSAFGTTNNTGGLFGNTQNKPGGLFGSSTFSQPVTSSTSSGFGFGATSGTSNSLFGSTNTGGGGLFSQQNNAFGANKPAAFGNFGTSTSSGGLFGTTNTASNPFGGTSGSLFGSSSFTAAPPGTTIKFNPPTGSDTMVKGGVTTSINTKHQCITAMKEYENKSLEELRLEDYQAGRKGPSNLPMAAGTGGLFGAAAPATPSTGTGLFGSSAPNTGFNFGQNKTTFGTSTGAFGTTTGSLFAQPQQQQQQQQQNSSLFKPFGSATTTQNNTFSFGNTSSMVSSSWCTKGLFANTAASQAGGLFGNTNTSTATGFGTGIFGQTNTGFGNVGTQNLFGNKPAGFGTTTTSAPSFGSGPGLFANKPTLTLGTNTNTSTFGFSGTGAGGGLFGNKTAATGLGPVLGAGFGAGVGTGQTSLFGNNQKLGSTLGSVGTFGAGGFNTGASTLNFGAPQQPIALTDPSAGAAQQAVLQQQISALAYSPFGDSPLFRNPLSDPKKKEERLKPTNPAAQKALTTPTQYKLTPRPATRVRPKALSSSGSSKSQLFDGLDDDELSLNNGAFMPRKSIKKLVLKNLNNSSLYNNSLNREADDLASPSEYPQNGLSLSLDEGEPREANMERRGEDDLEVSKFYTNPITKPIPHAQLSPLLQDTISEFNMRGSGSHRNGLEASSEDLSLAEDSIQEERDEELEAQKPPHPAGIVLSRVGYYTIPSMEELGKMLNENGECIVENFTIGRKGYGSVFFPGEVNLTNMILDEIVHFRRKEIIVYPDDKDKPPVGEGLNRRAEVTLDGVWPNDKTTCCQIKSPDRLTEMNYEGRLEAASRKQGARFLEYRPETGSWVFEVAHFSKYGLQESDEEEEISPAKLDLKKLKTAVPPGLAQLPLTQQQGAPQAQSTAVLELLSRVSELDSDMADITQEHPVESILDDEDGERTSFEENKLRSETPAENEPVSASSQIASSMGINPHTLQIMKASLFADDDECDMFQEHVSSKLIQDVASTKLLLSGAGRPSIGALLQNKFTSGGGLFSQLPEVPFSGISQKLNKSLASEAAWPSLGPSFLLPPPPPEPTLRTVGARRLGGPVPLEASITLGKGRLLMDAALFRGRSFRVGWGPNWTLVHSGDQLSVTHPVKEPAAENLGFGFLPKPTKTKPITESPFKVRVEQVVGLEPKQSSESLSLYLRPLEIGLKHSTINTEEPCPFIQPAGGVDALHGYAEWIVEVNKDIGGSDAGLAHWKQVWTLCAALWGRLGDRDLDTEQYSDYQQQLERRRSFSHWLSDCAANCIEEEVGRALQRSHAEAVFSYLTGHCISKACKLSQKSGDHRLSLMLSQAVGSQFCRDLLALQLTDWNRMQTDSFIEEERLRIFALLAGKPVWQSTDCCINVCSELDWKRCVAVHLWYMLPPTASVADALTKYETAFQGSEEVKRYAGPPLPPYIDELELLGLDEDMDEIDSKKPLYDICFHLLKLYSDRHYSLQQLLDPSTVTADHLDYRLSWHLWSVLQALNYNHLATSCQGLLHASYAAQLESAGLWEMAIFVLLHITDSGRRESAVREMLSLHCSLEETEESMEKEQFLTEKLLIPIQWIHQAKAIRACREGDKHREALHLYKAGHWNHCHRLVIQHLASDCIINDNHKYLLDFLEGLAVPERSVQIQGWDTSGRVFLDYIHVIQTLQDIQQMESPGYELERLHTEVTSLCNRIVLLPCSKAKDKLAQSEMAKRVANILRVVLSLQQGGEGTPDSQYIPLCQLASHIGRLPMPEDYALEELRSLTNSYMQEYVISH
Protein: Peroxisome targeting signal 1 receptor (Q57W55)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
Interaction partners:
- Nonspecific lipid-transfer protein, putative
- propanoyl-CoA C-acyltransferase
- Peroxisomal membrane protein PEX14
- Peroxin-7
- Peroxin-13
- Peroxisome assembly protein, putative
- RING-type E3 ubiquitin transferase
- non-specific serine/threonine protein kinase
- Peroxisomal ATPase PEX6
- Peroxisomal ATPase PEX1
Sequence:
MDCGAGFALGQQLAKDALHMQGGVRPGTTGNVEQDALMTGMMVPPTGPMEDWAQHFAAHQHHHQQHQQMMMQRQHNDALMIQQQHRDMEEAFRASARAGAPQQANAGPLMMPPGPMMMAGGMAPMMHAGGFMMGGMPQMMPCTPMGMNMGMAPVATMNPATTSTVSGAREGATAVSSAAPGVVDLGGDSAWAEKLHQAEWGQDYKDVEVHTVEGSTAQTVEEHAKTSKFYEFMDKIRKKELLVDEDSGEVVQGPGPDPDVEADTEYLARLAAMEGINVPPSVMDHMQGQDGVQRGTDEDMEGMMGDDVYDPSADVEQWAQEYAQMQAMQERLQNNTDYPFEANNPYMYHENPMEEGLSMLKLANLAEAALAFEAVCQKEPEREEAWRSLGLTQAENEKDGLAIIALNHARMLDPKDIAVHAALAVSHTNEHNANAALASLRAWLLSQPQYEQLGSVNLQADVDIDDLNVQSEDFFFAAPNEYRECRTLLHAALEMNPNDAQLHASLGVLYNLSNNYDSAAANLRRAVELRPDDAQLWNKLGATLANGNRPQEALDAYNRALDINPGYVRVMYNMAVSYSNMSQYDLAAKQLVRAIYMQVGGTTPTGEASREATRSMWDFFRMLLNVMNRPDLVELTYAQNVEPFAKEFGLQSMLL
Protein: Cyclin delta-3 (Q8RWU1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MHRGAAVFGRKRRLILLHGSRNFARSFCSSSSLSEHECFIKDIAKAQPPKHLMQLLNIFTARGKSIVSPGAKQGLLPLTIPLVKMSPGSSIALLRWPTAPSSMEMPVVEVQKHGVWFLANNVDQFIHRILVEEDVSKPEECSQEIFNAAGEAGKKLYSKGDFASSRLMDLDAYLLRKVGLFPDSLERKVIRHIENGDHVSALVATEFYTKRGNFPGFARPFAFNAKVLLKLGRNLEAKDAARGALKSSWWTLGCRYEEIAQIAEWGEEQIAQYKERVTGEGKQRDIDRGKPMAQASLDEAAFLLNLASLEGTWDESLERVAQCYKEAGLNDIAKFVLYRD
Protein: Probable serine/threonine-protein kinase FMP48 (EC 2.7.11.1) (Found in mitochondrial proteome protein 48) (P53233)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14576278}.
Interaction partners:
Sequence:
MYTKLRSIQSGTFSTVYKAWSTTHNRYVALKITPKYKTSEANMKNEYDVMKILSSCNPHPNICSMLDFYTDDSYYIMVLEYCECGDLYDFLDIAKSQGSPSSPSLIQIDMQKIIKQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAIQSPKSNDFQIGTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLFRVSKSKKVQHLKNFDEFEKDPFAFIYRKYVVPRLSCGYNDEEDLHVSLQHTRQYIWQDLPDIYDVFHLCKIMVDTLLKVSNAKERSMENFINEVDSAWNKDSSMDSCFSYQNKIDLFWEQWSVNTETVPAKFQLKNFEKPCLIQDGK
Protein: Cystatin-B (Cystatin-beta) (Liver thiol proteinase inhibitor) (Stefin-B) (P01041)
Organism: Rattus norvegicus (Rat)
Function: This is an intracellular thiol proteinase inhibitor.
Subcellular location: Cytoplasm.
Interaction partners:
- Cathepsin S
Sequence:
MMCGAPSATMPATTETQEIADKVKSQLEEKANQKFDVFKAISFRRQVVAGTNFFIKVDVGEEKCVHLRVFEPLPHENKPLTLSSYQTDKEKHDELTYF
Protein: Hexokinase-2 (EC 2.7.1.1) (Cytoplasmic antigenic protein 3) (Hexokinase PII) (Hexokinase-B) (P83776)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15378761}.
Interaction partners:
- ATP-dependent 6-phosphofructokinase
- Glucose-6-phosphate isomerase
- ATP-dependent 6-phosphofructokinase
- Fructose-bisphosphate aldolase
- phosphoglucomutase
- Phosphoglycerate kinase
- Phosphotransferase
- Mannose-6-phosphate isomerase
- Phosphotransferase
- Glucosamine 6-phosphate N-acetyltransferase
Sequence:
MVHLGPKPAQKRKGTFTDVSPQLLEALKPIQEQFTISADKLRAIVKHFISELDRGLSKAGGNIPMIPGWVMDFPTGKETGSYLAIDLGGTNLRVVLVKLGGNRDFDTTQSKFALPAHMRTATSDELWDFIAKCLKEFVDEIYPDGCSEPLPLGFTFSYPASQNRINEGILQRWTKGWSIDGIEGKDVVPMLQKAIKKVGVPIDVVALINDTTGTLVASMYTDPEAKMGLIFGTGVNGAYFDVVKDIPKLEGKCPSDIPPESPMAINCEYGSFDNEKYILPRTKYDVQIDEESPRPGQQTFEKMISGYYLGEVLRLILLEFAEEKKLIFKGQNLDKLKVPYVMDASYPSKIEEDPFENLSDVADLFREKLGIETTEPERKIIRCLAELIGERSARFSVCGIAAICQKRGYKTAHCAADGSVYNKYPGFKERTAQALRDIYEWPADVKDPIIIVPAEDGSGVGAAVIAALTEKRLKEGKSVGLLGA
Protein: Tetraspanin (Q7ZUH9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
Interaction partners:
Sequence:
MAAGGGLQCIKYLLFIFNFIFWLAGTGVLAVGLWLRFDAKTKEFFTAENGQTVFLTGVYILIVAGAVMMVVGFLGCCGAIKESACMLGLFFMFLLVIFAAEVAAGIWGLSNKDKIVSDVQQFYTQTVKNYKESPDGPLKETLTAIHFSLQCCGPTGLASDGVSVTCPKQEGLANVITTGCSSVIQDMFNSRLHVIGGVGIGIGVIMVFGMIFSMLLCCAIRRTRDIV
Protein: WD repeat domain 62, isoform H (M9PBP2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDAPDVGRIIRAPARRKRNDEQLMDRIKLKKVLGLTVCSNAALDVSPVSGLLAYPAGCTVVLFNAKRQTQAYLVNTSRKAFTSVAFSRCGRYVATGECGINPAIKVWELETPNGSLEHCSGGSVVAEFVDHKYAVTCVAFSPTGKYLVSVGSQHDMIVNVFDWRANLKMASNKISSKVAAVCFSEDGSYFVTVGNRHVKYWYLEGGRKYKDPIPLMGRSAILGDLRDNDFCAVACGKGICAESTYAITRQGHLVEFSSRRLLDKWVQCRTTNANCICVNERFILVGCAESIIRIFNSATLEYVTTLPRTHYLGVDVAQGIQINHIMSVPQQAKFPDCIAMVFDEQRSKVSCVYNDHSLYIWDLRDISRVGKSHSFLYHSTCIWGVETVPYNVEREPSQTLPEECFVTCSSDDTIRVWGLDGCTNNDIYRRNIYSKELLKIVYSDDELQFIKDQGSSLFDKAGNSSYDGRNGVRCIKISPELQHLASGDRCGNIRVYSLVNLRLLTTIEAHESEVLCLEYSNEKIERKLLASASRDRLIHVFDVAQNYLLLQTLDDHSSSITSIKFVGAGLNFQMISCGADKSIMFRSFQGNIFMRGTNTSGKTTLYDMEVDSNAKHILTACQDRNVRVYGTQNAKQTKTFKGSHSDEGSLIKLSLDPSGIYVATSCTDKTLAVYDYYSNECMARMYGHSELVTGLKFTNDCRHLISASGDGCIFIWQVPHDMIVTMQARMSQQRLRSGHAPLPRPLAPISPPDGIVLESPTSEIEQPQLQPKFGVAERFSDVGQLPQWAMRKAAADSDSGALSIPTPSGGSATVPGMHAASSMGNLSSSPSQQMTGLAPRARGRWAQRSTQLETADDLRSNSESPLGTVSSVGGHSGVNVQTSDYNSASSKDITYNQTYLSEDSSIDSGMETRRGELKFIGSSNNGTVVTVSSVSSIAVSASNGAMSTGSGAAQQRLQLPDKRLKPGLRFDTHTHDHDGDVEDISDGERTSSDHGMFYNNLAPSTPTDFKVTAMNEDELRKSVRRQKFEKSGLQLTPSALSGNGSSHTASTGTGTSDTEDEGSTPSAENAERSLASTLGGSSENLPQSSTNSFLHAALPEGPGLTTPMERGGSSRRSISAKHNTENGKSVAAPPTITKSYTSTKKEELLQVINKVKQQLENVGHRPLRGSHSISDLSLAANLDGSRNAGGGPGRYQKPAGKSQNGTPQKPQVQHRNGNVSRSASKRNSLQGKTGLGASSNSMNVLNQGSDSEPEDSNRLRSASNGQGRSNGPIAANRQYSNKINNVNNNRRKTPNFSSATPMQDDSSSEETPNSTVNNKPIVPPRPRNLAFDHKSKLMINNSGSPGGNAKQRSGVTSTEDFEGTDPEAQVHNVINKLYTTTQAAMQLHANLKNTLLLKELENALIMSRNMLSSITNRQADKTNNGGGGLGVGGSGGLNHDQLNADNGDYLMMVNNCADLLSNLRTKHKPDDCENNS