wanglab/gogpt-training-data huggingface dataset:
Protein: Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 1) (O70593)
Organism: Rattus norvegicus (Rat)
Function: Co-chaperone that binds misfolded and hydrophobic patches-containing client proteins in the cytosol. Mediates their targeting to the endoplasmic reticulum but also regulates their sorting to the proteasome when targeting fails. Functions in tail-anchored/type II transmembrane proteins membrane insertion constituting with ASNA1 and the BAG6 complex a targeting module. Functions upstream of the BAG6 complex and ASNA1, binding more rapidly the transmembrane domain of newly synthesized proteins. It is also involved in the regulation of the endoplasmic reticulum-associated misfolded protein catabolic process via its interaction with BAG6: collaborates with the BAG6 complex to maintain hydrophobic substrates in non-ubiquitinated states. Competes with RNF126 for interaction with BAG6, preventing the ubiquitination of client proteins associated with the BAG6 complex (By similarity). Binds directly to HSC70 and HSP70 and regulates their ATPase activity.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O43765}. Nucleus {ECO:0000250|UniProtKB:O43765}. Note=Co-localizes with HSP90AB1 in the cytoplasm. Increased nuclear accumulation seen during cell apoptosis. {ECO:0000250|UniProtKB:O43765}.
Interaction partners:
- Ubiquitin-like protein 4A
- Large proline-rich protein BAG6
- Guided entry of tail-anchored proteins factor 4
- Heat shock protein 105 kDa
- Heat shock 70 kDa protein 4
- ATPase Get3
- Heat shock cognate 71 kDa protein
- Heat shock cognate 71 kDa protein
- Guided entry of tail-anchored proteins factor 1
- BAG cochaperone 2.
Sequence:
MDNRKRLAYAIIQFLHGQLRHGGLSSDAQESLEVAIQCLETAFGVTLEDSDLALPQTLPEIFEAATASKEMPQDPRGPDRTPPSEEDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPANAVYFCNRAAAYSKLGNYVGAVQDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALELDPDNDTYKSNLKIAELKLREAPSPTGGVGSLDIAGLLNNPHFITMASSLMNSPQLQQLMSGMISGGHNPLGTPGSSPQHSDLASLIQAGQQFAQQMQQQNPEFVEQIRSQVVRSRTPSASHEEQQE
Protein: Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1) (Q6ZPE2)
Organism: Mus musculus (Mouse)
Function: Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location. May function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O95248}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O95248}. Cell projection, neuron projection {ECO:0000250|UniProtKB:O95248}. Note=Localized in neuronal somata and processes with punctate/vesicular morphology. {ECO:0000250|UniProtKB:O95248}.
Interaction partners:
- Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2
Sequence:
MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVESTQEVVCTDNATEKEEEADGGGQARLSSTAPAQPGQLFAPKTLVLVSRLDHAEVFRNSLGLIYAIHVEGLNVSLENVIGNLLTCTVPLAGGSQRTISLGAGDRQVIQTPLVDSLPVSRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAETQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHNVLSMVLDPELELADLAFPPPTTSASSLKMQDKELRAVFLRLFAQLLQGYRWCLHIVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRATDLFDELVAHEVARMRADESHPHRVLRHVQELAEQLYKNENPYPAVAMHKVQRPGEASHLRRTHRPFPRLDEGTIQWIVDQAAAKMQGAPPAVKAERRSTVPSGPPMTAILERCSGPHINSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAHELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIASALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPSDGVSPTQETGEAQSQDDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGDLESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGVGGSGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRISVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRATFAFTLGSAHTPGRPPRVTKDKGPSFRTLSRNLMKNAKKTIGRQYVTRKKYNPPGWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSIQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNTPSPGQAQADSSSLEQEKYLQAVVSSMPRYADSSGRNTLSSFSSAHMGGHGKWSSVRASGRSSGLGSDVGSRLAGRDLLSTPHTNGAPPDSGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQISVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHTSRRFRTFLLDSDYERIELGLLYEEKGERRGQLACKSVWEYVDRLSKRTPMFYNYTYAPEDTEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRVQPDAISRLLEELQRLETELGRPSERWKDTWDRVKAAQRLESRQDGRGTPSSLLVSAVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSSSRQAARRSTSTLYSQFQTAESENRSYEGILYKKGAFMKPWKARWFVLDKTKHQLRYYDHRMDTECKGVIDLAEVEAVAPGTPTIGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSDA
Protein: Na(+)-translocating NADH-quinone reductase subunit A (Na(+)-NQR subunit A) (Na(+)-translocating NQR subunit A) (EC 7.2.1.1) (NQR complex subunit A) (NQR-1 subunit A) (A5F5X1)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Interaction partners:
Sequence:
MITIKKGLDLPIAGTPSQVISDGKAIKKVALLGEEYVGMRPTMHVRVGDEVKKAQILFEDKKNPGVKFTSPVSGKVVEINRGAKRVLQSVVIEVAGDDQVTFDKFEANQLASLNRDAIKTQLVESGLWTAFRTRPFSKVPAIDSTSEAIFVTAMDTNPLAAEPTVVINEQSEAFVAGLDVLSALTTGKVYVCKKGTSLPRSQQPNVEEHVFDGPHPAGLAGTHMHFLYPVSADHVAWSINYQDVIAVGQLFLTGELYTQRVVSLAGPVVNKPRLVRTVMGASLEQLVDSEIMPGEVRIISGSVLSGTKATGPHAYLGRYHLQVSVLREGRDKELFGWAMPGKNKFSVTRSFLGHLFKGQVYNMTTTTNGSDRSMVPIGNYEKVMPLDMEPTLLLRDLCAGDSDSAVRLGALELDEEDLALCTFVCPGKYEYGQLLRECLDKIEKEG
Protein: Lysozyme (EC 3.2.1.17) (Q5AZ10)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MKGISLLALPGLAYAAVQGFDISNWQPTVDYKGAYASGARFVMIKATEGTSFIDPLFNTHYPGATSAGLIRGGYHFAHPDSSSGSAQAKYFLAHGGGWSGDGITLPGMLDLEAGCYGLSATAMVSWISDFGETYKSATGRYPMIYTTTSWWQECTGNNDGFGEYPLVLARWASTPGTLPASWDYYSFWQNSDSYAYGGDSQLWNGSEERLRIFASG
Protein: Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) (Serine/threonine-protein kinase PISSLRE) (Q15131)
Organism: Homo sapiens (Human)
Function: Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:27104747}.
Interaction partners:
- Protein C-ets-2
- Cyclin-Q
- Zinc finger protein 276
- Cyclin-L2
- Mitochondrial inner membrane m-AAA protease component paraplegin
- N-acetylgalactosamine-6-sulfatase
Sequence:
MAEPDLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP
Protein: Small ribosomal subunit protein RACK1 (B5DFX3)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
- Ubiquitin-like protein FUBI isoform X1
- 40S ribosomal protein S30
- 40S ribosomal protein S15
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein eL33
- 60S ribosomal protein L18
- Large ribosomal subunit protein eL38
- Eukaryotic translation initiation factor 3 subunit B
- 60S acidic ribosomal protein P0
- 60S acidic ribosomal protein P0
Sequence:
MTEQMTVRGTLKGHNGWVTQIATTPQFPDMILSASRDKSIIMWKLTRDETNYGIPQRALKGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDESHSEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDSGDNINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELRQEVISTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVTIGTR
Protein: Lysosome-associated membrane glycoprotein 5 (Q9GZD5)
Organism: Caenorhabditis elegans
Interaction partners:
- Vesicular GABA transporter
- Glutamate decarboxylase 1
- Transporter
Sequence:
MNLFYFLLISSFTDALTTSTAITSTGIESSFVHENQTIGLKKENGDTCISVTFQVKILNQQNNNSVPIDFHLPSGLIKGNCAVTRKSKAVISSTIEETDGRMKTLKFVFRTEEMRAKRLDELRWQLNKVIYEEKFAGSSAVFESDNSSVIFSAPLTQKYVCEDRINVTLHSVNFDFPILVMFSPEIDVQPYGPKSNFYICERSRKRTLSESLQHRSTVFCGVVLALSSIAHIVGHMLRRHFMPHRKELYENLDKLPAMN
Protein: Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) (O43447)
Organism: Homo sapiens (Human)
Function: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:9570313}. Cytoplasm {ECO:0000269|PubMed:9570313}. Note=Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic.
Interaction partners:
- NHP2-like protein 1
- U4/U6 small nuclear ribonucleoprotein Prp3
- U4/U6 small nuclear ribonucleoprotein Prp4
- U4/U6 small nuclear ribonucleoprotein Prp31
- Small nuclear ribonucleoprotein F
- Pre-mRNA-processing-splicing factor 8
- 116 kDa U5 small nuclear ribonucleoprotein component
- U6 snRNA-associated Sm-like protein LSm4
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein Sm D2
Sequence:
MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM
Protein: PRKR-interacting protein 1 (Q9H875)
Organism: Homo sapiens (Human)
Function: Required for pre-mRNA splicing as component of the spliceosome. Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:30705154}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9CWV6}.
Interaction partners:
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor SLU7
- Pre-mRNA-splicing factor SYF2
- Small nuclear ribonucleoprotein E
- Peptidyl-prolyl cis-trans isomerase-like 1
- Small nuclear ribonucleoprotein G
- Splicing factor Cactin
- U2 small nuclear ribonucleoprotein A'
- RNA helicase aquarius
- Protein FAM32A
Sequence:
MASPAASSVRPPRPKKEPQTLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMSEWAPRPPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQEGPGQPKEQGSSSSAEASGTEEEEEVPSFTMGR
Protein: At4g31130 (Keratin-associated protein (DUF1218)) (Q9M089)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MAVSMKQMSLVVSALGVLSFVLGVIAENKKPASGTPISGKGVVICKYPSDPTVALGYLSAAFLLACTVAGYKSLFISYKGKSVPNSVLFKSTSFSVFFNIALITSGLALSLLLWPTITEQLHLTRNVHRNLETSCPTAKTGLLGGGAFVSLDSCLFWLVALMLADNAREDHFDEVESRSIDGNSSSRDVNLKIDA
Protein: Uncharacterized transporter YaaJ (P30143)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Sodium/proline symporter
- DNA-binding and peroxide stress resistance protein YaaA
Sequence:
MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFGKSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIGMATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSGVQANAVARALSFSFDFPPLVTGIILAVFTLLAITRGLHGVARLMQGFVPLMAIIWVLTSLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMGSTPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQLIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRICTFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVRPVFDPLRYPDIGRQLSPDAWDDVSQE
Protein: Complement component C8 beta chain (Complement component 8 subunit beta) (P55314)
Organism: Rattus norvegicus (Rat)
Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Complement C5
- Complement component C8 gamma chain
- Complement C7.
- Complement component C9
- Complement C8 alpha chain
- Complement component C6
- Carboxypeptidase B2
- CD59 glycoprotein
- ADP/ATP translocase 2
- ADP/ATP translocase
Sequence:
MKTGAQVWRALAKSCLLCAALGCLHLPGARGEKPDFFETNAVNGSLVRSRPVRSVDVTPAPTDCQLSTWSSWTACDPCQKKRYRHTYLLRPSQFYGELCDFSDKEVEDCVTNRACRSQVRCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRRIYKKCSQDMEQYWAIGNLASGINLFTNTFEGPVLDHRYYAGACSPHYILNTNFRKPYNVESYTPQTQGKYEFALTEYESYFDFEHNVTEKATSKSSFKFGFKLDGLVEFGVRKESNEGRHYISRTKRFSHTKSKFLHARSVLEVAHYKLKSRQLMLHYEFLQRVKSLPLEYSYGEYRDLLRDFGTHFITEAVLGGIYEYTLIMNKDAMERGDYTLDHVSACAGGGFQIGGNVYKVYLKLGVSEKKCSDILNEIKDRNKRRTMVEDLVVLVRGGTSEYITSLAYKDLPTAELMKEWGDAVQYNPAIIKLKAEPLYELVTATDFAYSSTVKQNMKKALEEFQMEVSSCRCAPCRNNGVPILKESRCECICPAGFQGVACEVTNRKDIPIDGKWSCWSDWSPCSGGRKTRQRQCNNPAPQRGGSPCSGPASETLDC
Protein: Actin-related protein 2/3 complex subunit (O97182)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 3
- Actin-related protein 2/3 complex subunit 5
- Actin-related protein 2/3 complex subunit 2
- Actin-related protein 2/3 complex subunit 3
- RE12101p
- LD35927p
- WHAMM and JMY related, isoform B
Sequence:
MAETYTFGTSLASITCHAWNKDRTQIALSPNNHEIHIYSREGSDWKLADVLNQHDLRVMGIDWAKNTNRIVSCAADRNAYVWTQGDDGKWKPALVLLRINRAATCVKWSPAENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVTSLDWHPNNVLLLAGSTDYKVRVFSAFIKDIEEPPTPTPWGNRKPLGQLMAEFRNSQTSGGGWINSVSFSSDGNKVCWVGHDSCVSIADATNGNTVIRCRTGYLPFLSCEWVSPTSVVVAGYSCVPLLYSLTADGKLVLSGKLDKSQKKESSGITAMRIFQSMDRNMRTENTDTVVDSIHQNAITSVRLYAGDKASATKVSTSGVDGQLVIWNVEQGGINGGMRNLQI
Protein: FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Q54N80)
Organism: Dictyostelium discoideum (Social amoeba)
Function: PPIases accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- FK506-binding protein 6
Sequence:
MNKFLIALLVLATLAVSFSQEIGVSILKTDTPKGECKGKTASIGDYISLKYVGKFEDGTVFDSSEIHGGFSFNFTIGERKVIPGLEIGTINICEGEKRSIKIPYQLAYGENGIENAIPPRTDIYFDLEVVSIEGAPAQPFYYQLIPSVGTIIAFSMLAGFIVLVKFIIKRYPDESNSKKPAPGKPKKTKAAKQN
Protein: Methyltransferase type 11 domain-containing protein (Q38AD9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQGKVVSVHGADAQWYEPTQIPQDKYLKIVQGRNLFLVTFITGSAVIWGLSLIPQWCMYRSVSWMYRKYCRGRVLDLTPKVADARDVRYYEMSNAVRVEFIVKERVDDDEYKTDLSLSEEEQTERRRALTLGFMLKNDYNWAGSSITFDTVERRETEMPDFRKYDTVVIRNELLNMGQEGARKMLNSAAAYVKEGGYVLLMDFGKPRWPLLASLTRWFGAATRSSMNLTHDYGRWVAEDNCYSIIAERRCLMGVHYAFVLQRKP
Protein: Curved DNA-binding protein (42 kDa protein) (Q09184)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: A non-essential protein that preferentially binds curved DNA. Binds non-curved DNA with a much lower affinity.
Subcellular location: Nucleus.
Interaction partners:
- Probable nucleolar GTP-binding protein 1
- Pescadillo homolog
- Nucleolar GTP-binding protein 2
- Small ribosomal subunit protein uS9B
- GTPase grn1
- 60S ribosomal export protein nmd3
- Large ribosomal subunit protein uL29
- Pre-rRNA-processing protein crb3/ipi3
- Ribosome production factor 2 homolog
- Large ribosomal subunit protein uL24
Sequence:
MSTKEATSETAVDYSLSNPETVNKYKIAGEVSQNVIKKVVELCQPGAKIYDICVRGDELLNEAIKKVYRTKDAYKGIAFPTAVSPNDMAAHLSPLKSDPEANLALKSGDVVKILLGAHIDGFASLVATTTVVSEEPVTGPAADVIAAASAALKAAQRTIKPGNTNWQVTDIVDKIATSYGCKPVAGMLSHQQEREVIDGKKQVILNPSDSQRSEMDTFTFEEGEVYGVDILVSTSPSGKVKRSDIATRIYKKTDTTYMLKLQASRKVYSEIQTKFGPFPFSTRNISFDSRTNMGLNECTSHKLLFPYEVLLDKDGGIVAEFYSTIALTKKGTIILSDSEPKEDFIKSDKKVEDPEIVALLETPIKVTKNKKKSKKPSKANE
Protein: Acryloyl-coenzyme A reductase (Acryloyl-CoA reductase) (EC 1.3.1.84) (Q975C8)
Organism: Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
Function: Plays a role in autotrophic carbon fixation via the 3-hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl-CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA.
Interaction partners:
- 3-hydroxypropionyl-CoA dehydratase
- Acetyl-CoA/propionyl-CoA carboxylase alpha subunit
- Acetyl-CoA/propionyl-CoA carboxylase beta subunit
- Acetyl-CoA/propionyl-CoA carboxylase gamma subunit
- Alcohol dehydrogenase
- 3-hydroxypropionyl-coenzyme A synthetase
- Enoyl-CoA hydratase
- Enoyl-CoA hydratase
- Enoyl-CoA hydratase
- Uncharacterized protein
Sequence:
MKAIVVPGPKQGYKLEEVPDPKPGKDEVIIRVDRAALCYRDLLQLQGYYPRMKYPVILGHEVVGTIEEVGENIKGFEVGDKVISLLYAPDGTCEYCQIGEEAYCHHRLGYSEELDGFFAEKAKIKVTSLVKVPKGTPDEGAVLVPCVTGMIYRGIRRAGGIRKGELVLVTGASGGVGIHAIQVAKALGAKVIGVTTSEEKAKIIKQYADYVIVGTKFSEEAKKIGDVTLVIDTVGTPTFDESLKSLWMGGRIVQIGNVDPSQIYNLRLGYIILKDLKIVGHASATKKDAEDTLKLTQEGKIKPVIAGTVSLENIDEGYKMIKDKNKVGKVLVKP
Protein: Granule bound starch synthase (Q9XHN9)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast {ECO:0000256|ARBA:ARBA00004229}.
Interaction partners:
Sequence:
MSALTTSQLATSATGFGIADRSAPSSLLRHGFQGLKPRSPAGGDATSLSVTTSARATPKQQRSVQRGSRRFPSVVVYATGAGMNVVFVGAEMAPWSKTGGLGDVLGGLPPAMA
Protein: Kinesin-like protein KIN-14B (Kinesin CDKA-1-associated protein 2) (Kinesin-like protein KCA2) (Kinesin-like protein for actin-based chloroplast movement 2) (Q9FKP4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Kinesin-like protein required for chloroplast movements and anchor to the plasma membrane. Mediates chloroplast movement via chloroplast actin (cp-actin) filaments. Required for the chloroplast avoidance response under high intensity blue light. Mediates redundantly with CHUP1 the nuclear avoidance response under high intensity blue light. May be involved in division plane determination (Probable).
Subcellular location: Cell membrane {ECO:0000269|PubMed:20418504}.
Interaction partners:
- Protein CHUP1, chloroplastic
- KIN14B-interacting protein At4g14310
- Plastid division protein CDP1, chloroplastic
- Plastid division protein PDV1
- Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein
- Kinesin-like protein KIN-10A
- DNA ligase-like protein
- Cyclin-dependent kinase A-1
- Kinesin-like protein KIN-5A
- L-type lectin-domain containing receptor kinase VIII.2
Sequence:
MAEQKSTNMWNWEVTGFESKKSPSSEEGVHRTPSSMLRRYSIPKNSLPPHSSELASKVQSLKDKVQLAKDDYVGLRQEATDLQEYSNAKLERVTRYLGVLADKSRKLDQYALETEARISPLINEKKRLFNDLLTTKGNVKVFCRARPLFEDEGPSIIEFPDNCTIRVNTSDDTLSNPKKEFEFDRVYGPQVGQASLFSDVQPFVQSALDGSNVSIFAYGQTHAGKTYTMEGSNQDRGLYARCFEELMDLANSDSTSASQFSFSVSVFELYNEQVRDLLSGCQSNLPKINMGLRESVIELSQEKVDNPSEFMRVLNSAFQNRGNDKSKSTVTHLIVSIHICYSNTITRENVISKLSLVDLAGSEGLTVEDDNGDHVTDLLHVTNSISALGDVLSSLTSKRDTIPYENSFLTRILADSLGGSSKTLMIVNICPSARNLSEIMSCLNYAARARNTVPSLGNRDTIKKWRDVANDARKEVLEKERENQRLKQEVTGLKQALKEANDQCVLLYNEVQRAWRVSFTLQSDLKSENAMVVDKHKIEKEQNFQLRNQIAQLLQLEQEQKLQAQQQDSTIQNLQSKVKDLESQLSKALKSDMTRSRDPLEPQPRAAENTLDSSAVTKKLEEELKKRDALIERLHEENEKLFDRLTEKSVASSTQVSSPSSKASPTVQPADVDSAGTLPSSVDKNEGTITLVKSSSELVKTTPAGEYLTAALNDFDPEQYEGLAAIADGANKLLMLVLAAVIKAGASREHEILAEIRDSVFSFIRKMEPRRVMDTMLVSRVRILYIRSLLARSPELQSIKVSPVERFLEKPYTGRTRSSSGSSSPGRSPVRYYDEQIYGFKVNLKPEKKSKLVSVVSRIRGHDQDTGRQQVTGGKLREIQDEAKSFAIGNKPLAALFVHTPAGELQRQIRSWLAESFEFLSVTADDVSGVTTGQLELLSTAIMDGWMAGVGAAVPPHTDALGQLLSEYAKRVYTSQMQHLKDIAGTLASEEAEDAGQVAKLRSALESVDHKRRKILQQMRSDAALFTLEEGSSPVQNPSTAAEDSRLASLISLDAILKQVKEITRQASVHVLSKSKKKALLESLDELNERMPSLLDVDHPCAQREIDTAHQLVETIPEQEDNLQDEKRPSIDSISSTETDVSQWNVLQFNTGGSSAPFIIKCGANSNSELVIKADARIQEPKGGEIVRVVPRPSVLENMSLEEMKQVFGQLPEALSSLALARTADGTRARYSRLYRTLAMKVPSLRDLVGELEKGGVLKDTKST
Protein: Ribulose bisphosphate carboxylase large chain (RuBisCO large subunit) (EC 4.1.1.39) (P0C511)
Organism: Oryza sativa subsp. indica (Rice)
Function: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site (By similarity).
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Methylcrotonoyl-CoA carboxylase subunit alpha
- 4-hydroxyphenylpyruvate dioxygenase
- Ribulose bisphosphate carboxylase small subunit, chloroplastic
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Ribulose bisphosphate carboxylase small subunit, chloroplastic
- 3-methyl-2-oxobutanoate dehydrogenase
- beta-ketoacyl-[acyl-carrier-protein] synthase III
- Uncharacterized protein
- acetyl-CoA C-acyltransferase
- Uncharacterized protein
Sequence:
MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWKAIKFEFEPVDKLDS
Protein: Low density lipoprotein receptor-related protein 5 (Low-density lipoprotein receptor-related protein 5 isoform 1 precursor) (F1QTJ4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Axin-1
- Protein Wnt
- Dickkopf WNT-signaling pathway inhibitor 1b.
- Sclerostin
- Dickkopf WNT-signaling pathway inhibitor 1a.
- Dickkopf WNT-signaling pathway inhibitor 2.
- Protein Wnt-1
- Catenin beta-1
- Protein Wnt
- Protein Wnt-8a
Sequence:
MELKPGALAMEILLLELLLCCSLTVIRGSPLLLFANRRDVRLVDVEVGRSESAVVVSDLEDAAAVDFLFSEGLIFWTDVSEEAIKQTYYNLSTNSMKEATLGKGQTVVVSGLDSPDGLACDWLGHKLYWTDSETNRIEVANLDGTSRKVLFWQDLDQPRAIALNPSHRYMYWTDWGEEPRIERAGMDGSNRQIIVQKQIYWPNGLTIDLDEQKLYWADAKLSFIHRANLDGTSREAVVEGSLTHPFALTLYDETLYWTDWQTRSIHACNKHSGEKHREILNGIYSPMDIQVLGQERQPNIQTPCSERNGGCSHLCLLSPIPPFYSCACPTGVKLKEDGKTCRPGAEQVLLLARRTDLRRISLDLPDFTDIVLQVNDIRHAIAIDYDPVEGYVYWTDDELRAIRRARIDGSDAQTLITNEINHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRRVLISENLDEPRAIVLDPINGYMYWTDWGELPKIERANLDGTDRVVLLNTSLGWPNGLAIDYIAGKLYWGDAKTDKIEVINVDGTNRMTILEDKLPHIFGFTLLGEYIYWTDWQRRSIERVHIANSTREVIVEQLPDLMGLKATKVMEAEGTNGCAENNGGCSHLCFHRPQGLSCACPMGLELLSDLRTCVVPEAFLLFTNRADIRSISLGTNSNDVPIPLTGVKEASALDFDVLENRIYWTDVSTKTISRAFMNGSSVEPVIEFGLDYPEGMAVDWMGRNLYWADTGTNRIEVARLDGQYRQVLVCKDLDNPRSLALDPANGYMYWTEWGGRPRIARAHMDGSNIVTLVDKVGRANGLTIDYIDQRLYWTDLDTCMIESTNMQGLQREIVADDLPHPFGLTQYRDYIYWTDWNLRSIERADKRSGLNRTVVQGHLEYVMDILVFHSSRQDGANDCSQNNGQCAHLCLASPSGAQCRCASHYTLEANGRNCSSPSSFLLFSQKSSISRMVLGEQSPDMILPIHVMKNLRAISFDPLERLVYWVDGRQNIRRSRDDGTQASTVMTPNSDHPKQPHDLSLDPYSRTVYWTCETTNTINIHRMDGHIIGEVLKDDVDKPRAIVVNAEKGYMYFTTVQERSAKIEGASLDGTERESLFTTSLIRPVALALDNKLGKLFWVDADLKRIESSDLSGANRIVLQDSNILQPVGLTVLGDHLYWIDKQQQMIERVDKLTGEKRTRIQGRLQYLTGIHAVQYMETDEFATHPCSRDNGGCSHICIAKGDGTPRCSCPMHLVLLQNLLSCGEPPTCSSEQFTCATGEIDCIPMAWRCDGIAECADNSDEMNCPICSKLQFQCDKGQCVDIQVRCNGEPDCADGSDEQDCETICLSNQFRCGNSQCILKKQQCDSFPDCTDESDERFCDFPPPPNDLPRHTSTIGPVIGIILSVFVMGGMCFVCQRVVCRHYKGPNGGFPHEYISGTPHVPLNFIAPTNSQHGKGISCGKSMMSSVSLMGSSSSGAPLYDRNHVTGASSSSSSSTKGAFYPQMLNPPPSPATDRSLYNAEVFYSSNSPSTTRSYRPYLMRGVAPPTTPCSTDVCDSDYTTSRWKSNKYYMDLNSDSDPYPPPPTPRSQYMSAEESCPPSPSTERSYFHLCPPPPSPCTDSS