wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized membrane protein Rv3691 (O69659)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable conserved membrane protein
- Possible conserved membrane protein
- Probable conserved transmembrane protein
- Probable methanol dehydrogenase transcriptional regulatory protein MoxR2
- Probable transmembrane protein
- Phosphoribosylglycinamide formyltransferase 2
- Transposase
- Possible conserved transmembrane protein
- Possible conserved membrane protein
- Probable transposase for insertion sequence element IS1533
Sequence:
MGAGPVIPTRLATVRRRRPWRGVLLTLAAVAVVASIGTYLTAPRPGGAMAPASTSSTGGHALATLLGNHGVEVVVADSIADVEAAARPDSLLLVAQTQYLVDNALLDRLAKAPGDLLLVAPTSRTRTALTPQLRIAAASPFNSQPNCTLREANRAGSVQWGPSDTYQATGDLVLTSCYGGALVRFRAEGRTITVVGSSNFMTNGGLLPAGNAALAMNLAGNRPRLVWYAPDHIEGEMSSPSSLSDLIPENVHWTIWQLWLVVLLVALWKGRRIGPLVAEELPVVIRASETVEGRGRLYRSRRARDRAADALRTATLQRLRPRLGVGAGAPAPAVVTTIAQRSKADPPFVAYHLFGPAPATDNDLLQLARALDDIERQVTHS
Protein: Probable alpha-amylase 2 (AtAMY2) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) (Q8LFG1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable alpha-amylase that does not seem to be required for breakdown of transitory starch in leaves.
Subcellular location: Cytoplasm, cytosol {ECO:0000305}.
Interaction partners:
- 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic
- 4-alpha-glucanotransferase DPE2
- Alpha-glucan phosphorylase 1
- Isoamylase 3, chloroplastic
- alpha-D-xyloside xylohydrolase
- Alpha-glucan phosphorylase 2, cytosolic
- Isoamylase 1, chloroplastic
- 1,4-alpha-glucan-branching enzyme 3, chloroplastic/amyloplastic
- Isoamylase 2, chloroplastic
- 1,4-alpha-glucan-branching enzyme 2-1, chloroplastic/amyloplastic
Sequence:
MGYYNNVFDECNDQTDIGRVIRDGREVILQAYNWESHKYDWWRNLDGKVPDIAKSGFTSAWLPPPSQSLAPEGYLPQDLYSLNSAYGSEHLLKSLLRKMKQYKVRAMADIVINHRVGTTRGHGGMYNRYDGISLPWDEHAVTSCTGGLGNRSTGDNFNGVPNVDHTQHFVRKDIIGWLRWLRNTVGFQDFRFDFARGYSANYVKEYIGAAKPLFSVGECWDSCNYNGHGLDYNQDSHRQRIISWIDATGQISAAFDFTTKGILQEAVKGQYWRLCDAQGKPPGVMGWWPSRAVTFLDNHDTGSTQAHWPFPSHHVMEGYAYILTHPGIPCVFYDHFYDWGSSIHDQIVKLIDIRRRQDIHSRSTVRVLKAESNLYAAIVGEKICMKLGDGSWCPSGRDWTLATSGHRYAVWHK
Protein: Spectrin beta chain (A0A8I6G9M6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MTSATEFENVGNQPPYSRINARWDAPDDELDNDSSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRMLIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPQVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTISVLNSRKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYQRELALRSELIRQEKLEQLARRFDRKAAMRETWLNENQRLVTQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQELEKENYHDQKRISARKNNILRLWSYLQELLRSRRQRLEATLALQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKTITAATLQFTEGKGYQPCDPQVIQDRVSHLEQCFSELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLKQIFQEAEDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDAENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKEFLEELEESRGVMEHLENQAQGFPEEFRDSPDVTNRLQALRKLYQQVMAQAELRGHKLQEALDLYTVFGESDACELWMTEKGKWLDQMDIPNTLEDLEVVQHRFDILDQEMKTLMAQIDGVNLAANNLVESGHPRSGEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEETSKWIVDKTKVVESTKDLGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHPDQKEDIGQRQADVEKMWKGLQDALQGQELSLGEASKLQAFLQDLDDFKAWLSMAQKAVASEDMPESLPEAEQLLQQHAAIKEEIDAHKDDYHRVKASGEKVIEGQTDPDYQLLGQRLEGLDTDWDALWRMWESRGNTLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEAGIRKFEDFLVSMENNRDKVLSPVDSGNMLVSEGNLYSNKIKEKVQLIEDRHMKNNEKAQEVTALLKDNLELQNFLQNCKELTLWINDKLLTSPDISYDEARNLHNKWMKHQAFMAELASHQGWLENIVAEGRQLMAEKPQFTDVVSERLEALHKLWDELQTTTKAKTEQLSAARSSDLRLQTHADLSKWISAMEDQLRSDDLGKDLTTVNRMLVKLKRVEEQVNLRKEELEELFAEAPPLGAEAGDTDMSIEKRFLDLLEPLGRRKKQLELSKAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHAPRVEDVLHRGQELVKAAEIDCQDIEERLGHLQSSWDTLREAAAGRLQRLREAHEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEEYGRNIKQLAGRAQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRKLENMYHLFQLKREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVNSIIERLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYFYTGTEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKADAIQSKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQERPRDVSSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMNDKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEKPTTRHLSLKRDCVSFRPQEEEGETAGEAPQVHHAATERTSPGEERGPWPQDLQPPPLPGHHKDEQEKSVGDERPATEPLFKVLDTPLSEGDEPTTLPAQRDLGHTVQMEGYLGRKHDLEGPNKKASNRSWNNLYCVLRNSQLTFYKDAKNLALGVPYHGEEPLALRHAICEIAVNYKKKKHVFKLRLSNGSEWLFHGKDEEEMLLWLQGMSTAINESQSIRVKAQSLPLPSLAGPDASVGKKDKEKRFSFFPKKK
Protein: Reproductive homeobox 2A (G3UYY0)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MERQSVNYKLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPEFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQVDKSNRKE
Protein: Transcription factor elt-7 (O61924)
Organism: Caenorhabditis elegans
Function: Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3'. Required for gut-specific differentiation, specifically acting with the GATA region-binding transcription factor elt-2 to control normal gene expression and promote normal formation of the intestine. May have a protective role in response to infection by Gram-negative bacteria such as P.aeruginosa.
Subcellular location: Nucleus {ECO:0000305|PubMed:20807527}.
Interaction partners:
- GATA-type domain-containing protein
- GATA-type domain-containing protein
- Defective pharyngeal development protein 4
- T-box transcription factor tbx-35
Sequence:
MLPETTTLQPLPSVTTIMNEPPARSPMEDYYLFNQFQYNQNPYVYPPQPVYYNTWQDASTHHFDPFQSYQIPSPYEQPIQSSMCTTPLQPLEDSRIIFDESLTKNENEQKSFVEQDSSYESSGNRFGSQKGKKIAKVIRDACCSHCSTTTTTLWRKNDEGNLECNACNLYYRHNKVKRPLSLCKQKPTTRKRRQAKKE
Protein: Mpv17-like protein (M-LP homolog) (M-LPH) (Q2QL34)
Organism: Homo sapiens (Human)
Function: Isoform 1 participates in reactive oxygen species metabolism by up- or down-regulation of the genes of antioxidant enzymes.
Subcellular location: [Isoform 1]: Peroxisome membrane {ECO:0000269|PubMed:16631601}; Multi-pass membrane protein.
Interaction partners:
- Mitochondrial inner membrane protein Mpv17
- Mpv17-like protein 2
Sequence:
MAGWWPALSRAARRHPWPTNVLLYGSLVSAGDALQQRLQGREANWRQTRRVATLVVTFHANFNYVWLRLLERALPGRAPHALLAKLLCDQVVGAPIAVSAFYVGMSILQGKDDIFLDLKQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFICFSQQSGDGTFKSAFTILYTKGTSATEGYPKK
Protein: Raf homolog serine/threonine-protein kinase (EC 2.7.11.1) (Abnormal cell lineage protein 45) (Q07292)
Organism: Caenorhabditis elegans
Function: Protein kinase that participates in the induction of vulva and has roles in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Plays a role in responses to M.nematophilum-mediated bacterial infection by promoting tail swelling and preventing constipation. Positively regulates lifespan upstream of mek-2 and mpk-1.
Interaction partners:
- Ras protein let-60
- Dual specificity mitogen-activated protein kinase kinase mek-2
- small monomeric GTPase
- Tyrosine protein-kinase src-1
- mitogen-activated protein kinase kinase
- 14-3-3-like protein 2
- Ras-related protein Rap-1
- Serine/threonine-protein phosphatase 5
- Sex muscle abnormal protein 5
- Kinase suppressor of Ras A
Sequence:
MSRINFKKSSASTTPTSPHCPSPRLISLPRCASSSIDRKDQASPMASPSTPLYPKHSDSLHSLSGHHSAGGAGTSDKEPPKFKYKMIMVHLPFDQHSRVEVRPGETARDAISKLLKKRNITPQLCHVNASSDPKQESIELSLTMEEIASRLPGNELWVHSEYLNTVSSIKHAIVRRTFIPPKSCDVCNNPIWMMGFRCEFCQFKFHQRCSSFAPLYCDLLQSVPKNEDLVKELFGIASQVEGPDRSVAEIVLANLAPTSGQSPAATPDSSHPDLTSIKRTGGVKRHPMAVSPQNETSQLSPSGPYPRDRSSSAPNINAINDEATVQHNQRILDALEAQRLEEESRDKTGSLLSTQARHRPHFQSGHILSGARMNRLHPLVDCTPLGSNSPSSTCSSPPGGLIGQPTLGQSPNVSGSTTSSLVAAHLHTLPLTPPQSAPPQKISPGFFRNRSRSPGERLDAQRPRPPQKPHHEDWEILPNEFIIQYKVGSGSFGTVYRGEFFGTVAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLLFMGWVREPEIAIITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLERLRDIILPKLTRSQSAPNVLHLDSQYSVMDAVMRSQMLSWSYIPPATAKTPQSAAAAAAANKKAYYNVYGLI
Protein: Stonin-2 (Stoned B) (Q8WXE9)
Organism: Homo sapiens (Human)
Function: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11381094}. Membrane {ECO:0000269|PubMed:11381094}. Synapse, synaptosome {ECO:0000250}. Note=Some fraction is membrane-associated.
Interaction partners:
- Epidermal growth factor receptor substrate 15
- Synaptotagmin-1
- Epidermal growth factor receptor substrate 15-like 1
- Intersectin-1
- Transcription initiation factor IIA subunit 1
- Synaptotagmin-2
- AP-2 complex subunit mu
- Clathrin coat assembly protein AP180
- Intersectin-2
- Phosphatidylinositol-binding clathrin assembly protein
Sequence:
MTTLDHVIATHQSEWVSFNEEPPFPAHSQGGTEEHLPGLSSSPDQSESSSGENHVVDGGSQDHSHSEQDDSSEKMGLISEAASPPGSPEQPPPDLASAISNWVQFEDDTPWASTSPPHQETAETALPLTMPCWTCPSFDSLGRCPLTSESSWTTHSEDTSSPSFGCSYTDLQLINAEEQTSGQASGADSTDNSSSLQEDEEVEMEAISWQASSPAMNGHPAPPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPNTPPSASVIPDVPYNSMGSFKKRDRPKSTLMNFSKVQKLDISSLNRTPSVTEASPWRATNPFLNETLQDVQPSPINPFSAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQIDDPDHFGSATLPDDDPVAWIELDAHPPGSARSQPRDGWPMMLRIPEKKNIMSSRHWGPIFVKLTDTGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHTAEREQVIKLGTTNYDDFLSFIHAVQDRLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGIVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILVKGNEIVLRQDIMPTTTTKWIKLHECRFHGCVDEDVFHNSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENVMIRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKASVRSISVEDKTDVRKWVNYSAHYSYQVALGSIWLMLPTPFVHPTTLPLLFLLAMLTMFAW
Protein: Stage 0 sporulation protein A (Stage 0 sporulation protein C) (Stage 0 sporulation protein G) (P06534)
Organism: Bacillus subtilis (strain 168)
Function: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Sporulation initiation phosphotransferase B
- Transition state regulatory protein AbrB
- Sporulation kinase D
- Sporulation kinase C
- Sporulation kinase E
- HTH-type transcriptional regulator SinR
- SpoIVB peptidase
- Sporulation kinase B
- RNA polymerase sigma-F factor
- RNA polymerase sigma-H factor
Sequence:
MEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLFKEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS
Protein: PKHD-type hydroxylase YbiX (EC 1.14.11.-) (P75779)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Catecholate siderophore receptor Fiu
- Uncharacterized protein YbiI
- Colicin I receptor
- Hydroxamate siderophore receptor FhuE
- Proofreading thioesterase EntH
- Enterobactin synthase component B
- 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
- Uncharacterized protein YdiE
Sequence:
MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNLLREWSEI
Protein: Chromatin structure-remodeling complex subunit RSC1 (A0A1D8PCV8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Chromatin structure-remodeling complex protein RSC8
- RSC chromatin remodeling complex ATPase subunit
- RFX-type winged-helix domain-containing protein
- Npl6p
- Bromo domain-containing protein
- Chromatin structure-remodeling complex subunit SFH1
- Arp9p
- Chromatin structure-remodeling complex protein RSC58
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MSEREKKKLSTKLQSLFNGIYKIEDNGYLIHPTFQTLPLRSGTDYYKVVQNPLSLHAVGRKLKNLKYADAQEFINDLALISWNARFYNHSKSVIYRQAQILKQYITDVVIPKLKNDKAVPNGHSLIYPHIGDLPDDRDNDELSGFSFEKGESTPGPSGASNAGSRRDEFEMSATPQADSMVALSKPLVSTGYTRSSFTTPSRPTRQKHKDNQIESGIRRGRPPIIDKPFETRIKLILKGFKKLRDNNGHPLTKHFEKLPDIKTHGDYYERIAAPISLNEIRIKVRSRKYSSVELFINDLDLMFANAQLYYENDPYSEEFLDSQQFKKEAHLVIQTELSKSDKEIILATSSSSDGVLRFPLEVLEVDGYTYKIGNWVLMKNPADPERPIVGQIFRMWSTEDGKRYVNMCWYYRPEQTCHAVDRLFFLNEVCKTGQYRDHLVDDIVGPCYVIFLTRYQKGDLPEGVIPESAPWFICEFRYNENTHVFNRIRTWKACLPDEVREDPEQPLIPLKETRKLIKYESPIKGLLAPDAYKGMEIPDAIPGTANSPPVSGSVYIGAPLPNDDLGQYISSQNVDAVPEHDETKSGRRAFLFTPISQLKGGGGSTNTVYATGPAVPHGTISHVPAKPIADIPGLTPSVARNTNILINREEKHQLPGSYKSLQEQIQENQAKKQQEQQLQQLQQQQHQQLYKKTSTPTPTSIAPTGTTYHTSMSTYSNLLVGGTLAYGLNESIGELGQFVNKKRKIGNNGKQDEEILFYRAPPLKLVGNKIITNSNVELGHSATYLAWKLKQNKSN
Protein: MAp19 (Q6Q1Q7)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MRLLLLLAVLCGGANSSIVLQKMYGRITSPDFPNNYPNHKERTWNVTVPKGYAVRIYFTHFNLELSYQCEYDYVKLSSSGKTLATLCGQDSTDTEEAPGNKTYISIDNTLTVVFRSDYSNEKPFTGFEAFYAAEDIDECKQLFDGEPLCSHHCHNYVGGYYCSCRIGYVLHENKRTCTA
Protein: Nuclear receptor subfamily 5 group A member 2 (Fetoprotein transcription factor) (mFTF) (Liver receptor homolog 1) (LRH-1) (P45448)
Organism: Mus musculus (Mouse)
Function: Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development (By similarity). Activates the transcription of CYP2C38.
Subcellular location: Nucleus {ECO:0000269|PubMed:33441767, ECO:0000269|PubMed:36423263}. Chromosome {ECO:0000269|PubMed:15014077}.
Interaction partners:
- Nuclear receptor subfamily 0 group B member 2
- Nuclear receptor subfamily 0 group B member 1
- Catenin beta-1
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Nuclear receptor coactivator 2
- Cytochrome P450 7A1
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
- Homeobox protein NANOG
- Bile acid receptor
- Krueppel-like factor 4
Sequence:
MSASLDTGDFQEFLKHGLTAIASAPGSETRHSPKREEQLREKRAGLPDRHRRPIPARSRLVMLPKVETEAPGLVRSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNQKRYTCIENQNCQIDKTQRKRCPYCRFKKCIDVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTSAIQNIHSASKGLPLSHVALPPTDYDRSPFVTSPISMTMPPHSSLHGYQPYGHFPSRAIKSEYPDPYSSSPESMMGYSYMDGYQTNSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQSNRNRQEKLSAFGLLCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVAHGKEGTIFLVTGEHVDYSTIISHTEVAFNNLLSLAQELVVRLRSLQFDQREFVCLKFLVLFSSDVKNLENLQLVEGVQEQVNAALLDYTVCNYPQQTEKFGQLLLRLPEIRAISKQAEDYLYYKHVNGDVPYNNLLIEMLHAKRA
Protein: APS-reductase (Q9SDP3)
Organism: Allium cepa (Onion)
Interaction partners:
Sequence:
MASATSTAAISGSISAHGLLHHDVKVAQIGNLGIQLKNCNINTSLINKKRWSVHAVDPAKATAGAVSDQFVEKKNLNDINDETVEDFDKLAADLENASPLEIMDRALAKFGGDIAIAFSGAEDVALIEYARLTGFDLVEKHYNIHIEYMFPDAVEVQGLVRNKGLFSFYEDGHQECCRVRKVRPLRRALKGLKAWITGQRKDQSPGTRAHIPVVQVDPVFEGLEGGVGSLVKWNPLANVEGNNVWNFLRTMDVPVNSLHTKGYVSIGCEPCTRPVLPGQHEREGRWWWEDAKAKECGLHKGNIASADSKDSTTGGLTPATERISDLFKSGSIVDLTRPGMENLLKIENKQDAWIVVLYAPWCQFCQGMESSYVELAEKLSGSGVKVGKFRADGDQKEFAQQKLQLQTFPTVLFFPKFAAGPVKYPSEKRDVDSLLAFVNALR
Protein: Photosystem II reaction center protein K (PSII-K) (Q6ENJ4)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00441}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00441}.
Interaction partners:
- Cytochrome b559 subunit alpha
- Photosystem II reaction center protein H
- Cytochrome b559 subunit beta
- Photosystem II reaction center protein L
- Photosystem II reaction center protein I
- Photosystem II CP47 reaction center protein
- Photosystem II CP43 reaction center protein
- Photosystem II reaction center protein J
- Photosystem II reaction center protein Z
- Uncharacterized protein
Sequence:
MPNILSLTCICFNSVIYPTSFFFAKLPEAYAIFNPIVDFMPVIPVLFFLLAFVWQAAVSFR
Protein: Calcium-binding protein 4b (Q9GYD9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Probable serine/threonine-protein kinase roco8
- Probable serine/threonine-protein kinase qkgA
- Probable serine/threonine-protein kinase roco5
- Probable serine/threonine-protein kinase roco6
- Probable serine/threonine-protein kinase roco11
Sequence:
MVTKKEFLEELTNATNEAIKAADKNGDNQLSKKEVNDMYKKCKYPNPTLATNSLFELFDLDKDGKLSVNEVKTAVLVDYIIEAETCLKKFVDIIFKADSNKDNKITWDEARQYFITSGSNEAQAKVLANSMFEDVDSDDDKCITREELREYAIEYFEIYPTE
Protein: Cytosolic phospholipase A2 zeta (cPLA2-zeta) (EC 3.1.1.4) (Phospholipase A2 group IVF) (Q50L41)
Organism: Mus musculus (Mouse)
Function: Has calcium-dependent phospholipase and lysophospholipase activities with a potential role in membrane lipid remodeling and biosynthesis of lipid mediators. Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis. In myocardial mitochondria, plays a major role in arachidonate release that is metabolically channeled to the formation of cardioprotective eicosanoids, epoxyeicosatrienoates (EETs) (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:15866882, ECO:0000269|PubMed:17293613}. Cell membrane {ECO:0000269|PubMed:17293613}; Peripheral membrane protein {ECO:0000305}. Mitochondrion {ECO:0000250|UniProtKB:Q68DD2}.
Interaction partners:
- Polyunsaturated fatty acid 5-lipoxygenase
- Polyunsaturated fatty acid lipoxygenase ALOX15
- Arachidonate 12-lipoxygenase, 12R-type
- Mitogen-activated protein kinase 3
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- Polyunsaturated fatty acid lipoxygenase ALOX8
- Cytochrome P450 2U1
- Mitogen-activated protein kinase 1
- Phosphatidylserine synthase 1
- Phospholipase A and acyltransferase 3
Sequence:
MPWTLQPKWLAGKGLPLLGAILLRKTEKSEPQWKHRRQETHPYYDLQVKVLRARNIQHTDKLSKADCYVRLWLPTASVSPSQTRTVVNSSDPEWNETFPYQIHGAVKNVLELALYDEDVLDSDNVFSILFDTSTLQLGQPCTKNFTRQQDPKELEVEFTLEKSQTPASEVVTNGVLVAHPCLRIQGTVTGDKTASLGELGSRQIQLAVPGAYEKPQPLQPTSEPGLPVNFTFHVNPVLSPKLHIKLQEQLQVFHSGPSDELEAQTSKMDKASILLSSLPLNEELTKLVDLEEGQQVSLRMKADMSSSGDLDLRLGFDLCDGEQEFLDKRKQVASKALQRVMGLSEALHCDQVPVVAVLGSGGGTRAMTSLYGSLAGLQELGLLDAVTYLSGVSGSSWCISTLYRDPSWSQKALQGPIKYASERVCSSKIGMLSPKQFEYYSREKRAWESRGHSMSFTDLWGLIIEYFLNQEENPAKLSDQQETVSQGQNPYPIYASINVHKNISGDDFAEWCEFTPYEVGFPKYGAYVPTELFGSEFFMGRLLHFWPEPRICYLQGMWGSAFAASLYEIFLKLGGLSLSFLDWHRGSVSVTDDWPKLRKQDPTRLPTRLFTPMSSFSQAVLDIFTSRITCAQTFNFTRGLCMYKDYTARKDFVVSEDAWHSHNYGYPDACPNQLTPMKDFLSLVDGGFAINSPFPLVLQPQRAVDLIVSFDYSLEGPFEVLQVTEKYCRDRGIPFPRIEVDPKDSEDPRECYLFAEAEDPCSPIVLHFPLVNRTFRTHLAPGVERQTAEEKAFGDFIINGPDTAYGMMDFTYEPKEFDRLVTLSRYNVLNNKETIRHALQLALDRRRQAGGRVGG
Protein: Rho-type guanine nucleotide exchange factor, isoform G (M9PGB1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell projection, lamellipodium {ECO:0000256|ARBA:ARBA00004510}.
Interaction partners:
Sequence:
MDQPLVVQAEYSFMGSNNDELCFQKGDVITVTQREDGGWWEGTLNDKTGWFPSNYVNECKVQLPLTETIRPPEEIQEYRSVVLKDLLDSERAHVAELQGLLENFLEPMQQTQILSQDEYAQLMCNFVEIVRTHEDLLIQIEECNDRVGKLFLTSAPLMKKVHQAYCAAHPKAIVILDKYKDELEKYMERQGAATPGLLVLTTGLSKPFRRLDKYSAMLQELERHMESSHPDRGDTQRSVAVYKDIAATCSATRRQKELELQVLTGPVRGWQGQELSTLGDIIHMGSVAVGADHRDRYFVLFPQTLLFLSVSQRMSAFIYEGKLPLTGIIVNRLEDTDALKNAFEISSPLIDRIVAVCQGPNEANKWVELLNANNPSLPMGIKRQLSNLSNSSLGHLNAAHMSPPSSHILLPPGGRPPATPSSIPAGSSSGGSHSHQGSPATNSMSHHKRSQSFNHHLSYNQYTPTQPPPHHLHPPQPPSLPSHLGASGPRSSSAQTPNSKTAAPLQASSMDASPAIQAAAAAAAAAVGMGVPSARKGSTKANWTISCLRPTPPLRPSLLNATSGSGSGSGGSGGGGSSSSNALASYCSGRKNQPTYEEDALVLRVFEAYCAAYQNNARNTIHSALQPWTPCLPIRGGKLKTSKTFSTSNPQLPFIANVGNSAYLNQHQQQHLQQQHLQQQHLQQQHLAQQQPGRQHSAGSLNSSFIWREASPNNFNLYSSSVSSSLNATPAQRYSLSGTAGGSTSIKDYQRALSEERATRKSLNRLKSGFGSGYDNVCTSPLLPRKNKPAPKLVAQQSYQRSPGNATATTIVKPNPPGHPGLYDRRLNRSFETSTSHRYAGYGAGYLMNCGGALRTSTLQRSTPQLAGGERSDDSDVERELLRGNGAGPTASLELNPDGSKRQSGSWCCGNFVMKQWRKINHV
Protein: Peptidase S53 domain-containing protein (Q54G77)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MRVLLLLVFLVFCIIPAALSFRDTNWSKYNRAGKKETVDFRIALNQRNLDVLENTLLDVSNPESPNYGKHWTSEQVADLVAPEPYVSKKVANYLKKNGCHNVENHRDYIKATGPVDSVEKIFSVEMYNYKHNIKSDQAIIRSSETYQVPFEISQYVHIVSGISELPHLKSGPKSQRLRPNPKDFQATPAPAGPADPGMVVPQTIQQLYGIPSNYQNNQNTSLCLAEFAADRSYQPKDLKTFAAKTGTPLINVVKNVGPFQPTQPDLESTLDVQYGGATAQTADVWFWTVNGWMYEFSSDLAATVPAPYVVSMSWGWPEPLQCQQGIGNCTDGESSQDYVNRVNIEFQKIGLRGITLLASSGDQGAPGDGNPSCTSRDQPISTIFPGASPWVTSVGATMLAAPSTSNPNPIDTSDAPVCGIHACATSTQEVTCSSPSALITTGGGFSNYSPQPAWQSKAVNAYLNSGVVLPNKKFFNASNRGFPDVSGLGHNYYIVAADQMNLVDGTSCSSPVIGGIVALLNSYRLDNGKSTLGFINPVLYAAYASNPAAFNDITVGNNYCTESCCATTGFVATKGWDAVTGLGSPNFKPLLSYIQSLN
Protein: Protein stn1 (Q0E7J7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for telomere maintenance.
Subcellular location: Nucleus {ECO:0000269|PubMed:17715303}. Chromosome, telomere {ECO:0000269|PubMed:17715303}.
Interaction partners:
- Protein ten1
- Protection of telomeres protein tpz1
- Protection of telomeres protein poz1
- Coiled-coil quantitatively-enriched protein 1
- DNA-binding protein rap1
- Telomere length regulator taz1
- Telomerase reverse transcriptase
- Protection of telomeres protein 1
- Ubiquitin-like protein pmt3/smt3
Sequence:
MLENENQLTHQFPTLSRWNPMFISDVHKISFHPHLQRYIGFWMGFPIRWIQIVGYIAAIDIYEGKHVLTVDDCSGMVLRVVFIIQDDFSMSKRAISMSPGNVVCVFGKINSFRSEVELIAQSFEELRDPNDEWKAWQKRMRYKKNLTKISKNHHSIIRTPKKSYFPKDHAKELLKCIRQMCKLNVQAGFTIEELIIYLKAKELHLPLVHIFNVENEIVENCDGNHILALNFSLQTLLQHGRIVRKSNSVYMLVTSKDIIRFVIPLMASGLLEAHKVQSIVRDSNPMFITLPLSAIAKHICQFLLRTKGKWRQAKKYTWVRDNQFV
Protein: Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22) (Q15435)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of protein phosphatase 1.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- E3 ubiquitin-protein ligase PPP1R11
- PAS domain-containing serine/threonine-protein kinase
- UBX domain-containing protein 2B
- Protein phosphatase inhibitor 2
- Protein phosphatase 1 regulatory subunit 3A
- Protein phosphatase 1 regulatory inhibitor subunit 16B
- Tetratricopeptide repeat protein 1
Sequence:
MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF