wanglab/gogpt-training-data huggingface dataset:
Protein: Solute carrier family 12 member 3 (Na-Cl cotransporter) (NCC) (Na-Cl symporter) (Thiazide-sensitive sodium-chloride cotransporter) (P55017)
Organism: Homo sapiens (Human)
Function: Electroneutral sodium and chloride ion cotransporter. In kidney distal convoluted tubules, key mediator of sodium and chloride reabsorption. Receptor for the pro-inflammatory cytokine IL18. Contributes to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2. May act either independently of IL18R1, or in a complex with IL18R1 (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:22009145, ECO:0000269|PubMed:36370249}; Multi-pass membrane protein {ECO:0000269|PubMed:36351028, ECO:0000269|PubMed:36792826}. Apical cell membrane {ECO:0000250|UniProtKB:P59158}; Multi-pass membrane protein {ECO:0000269|PubMed:36351028, ECO:0000269|PubMed:36792826}.
Interaction partners:
- Serine/threonine-protein kinase WNK4
- Chloride channel protein ClC-Kb
- ATP-sensitive inward rectifier potassium channel 1
- Serine/threonine-protein kinase WNK1
- Serine/threonine-protein kinase WNK3
- STE20/SPS1-related proline-alanine-rich protein kinase
- Barttin
- Claudin-16
- Chloride channel protein ClC-Ka
- Serine/threonine-protein kinase OSR1
Sequence:
MAELPTTETPGDATLCSGRFTISTLLSSDEPSPPAAYDSSHPSHLTHSSTFCMRTFGYNTIDVVPTYEHYANSTQPGEPRKVRPTLADLHSFLKQEGRHLHALAFDSRPSHEMTDGLVEGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPIVDPINDIRIIAVVSVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYLVGTLIPPSEDKASKGFFSYRADIFVQNLVPDWRGPDGTFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSCVVRDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARVDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVFVGGQINRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRAEHTKRFEDMIAPFRLNDGFKDEATVNEMRRDCPWKISDEEITKNRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLETLSQDLRPPVILIRGNQENVLTFYCQ
Protein: Peptidase, mitochondrial processing subunit alpha (Q5SXN9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEEVEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHSYLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVDTVELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIREYRRGSEGLPQASARLRGGRLALPQAVVGLWYVHHTQNLGPSPVVLSRGGQGQGRGVADLVSLPGPTMHLLPPWQVTPPSAPLGGAVTTAQSC
Protein: RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf-1) (D3KYU7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
Sequence:
MEQLQGAWRTVTNGLLTKDSVFESSYVSPVIKSPAPCQSRSSDDSKTSRTIRVFLPNQQRTVVNVRPGMTLHSCLIKALKVRGLQPECCAVFSLHPGQRSKKSRMEWSTDSTSLIGEELLVEVLDHVPLTTHNFVRKTFLKLAFCDICQKFLLNGFRCQRCGYKFHEHCSTKVPTMCVDWTNIRQLLLFPTPGESGAPSLPSLTSRRMRESLTRIPSSSVHRYSNPHVSNYTSPYPPSGAALTQRLRSTSTPNVTMLSTTVPVDSSLIEDAIRVHSSAGSSPNQSPTGWNQASAHIPASALNPQEKVKIRPRDKRDSSYYWEIEANEVVLLSRIGSGSFGTVHKGKWHGDVAVKVLKVTNPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKGNLAIVTQWCEGSSLYKHLHVLETNFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKARWSGSQQVEQPSGSILWMAPEVIRMQDNNPYSFQSDVYSYGIVLFELMTGELPYSQIGNRDQIIFMVGRGYLSPDLSKLYKRCPKAMKRLVADCIKKSKDERPLFPQILSSIELLQHSLPKINRSASEPSLHRASQSEDISSCTLTSMKLPVF
Protein: Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C) (Q7Z406)
Organism: Homo sapiens (Human)
Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.
Interaction partners:
- Actin, cytoplasmic 2
- Myosin light polypeptide 6
- Myosin regulatory light chain 12A
- Myosin regulatory light polypeptide 9
- Small ribosomal subunit protein uS12m
- Myosin regulatory light chain 12B
- Myosin-9
- Myosin light chain 6B
- Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
- Myosin-1
Sequence:
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Protein: 11-oxo-beta-amyrin 30-oxidase (EC 1.14.14.115) (Cytochrome P450 72A154) (H1A988)
Organism: Glycyrrhiza uralensis (Chinese licorice) (Glycyrrhiza shiheziensis)
Function: Involved in the biosynthesis of Glycyrrhetinic acid (GA), a natural product which exhibits anti-inflammatory activity. Involved in the biosynthesis of the triterpenoid saponin glycyrrhizin. Catalyzes three sequential oxidation steps at C-30 of 11-oxo-beta-amyrin. Also able to catalyze C-30 monohydroxylation of beta-amyrin to produce 30-hydroxy-beta-amyrin. May be also responsible for the oxidation at positions C-22 and C-29 in addition to C-30.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MDASSTPGAIWVVLTVILAAIPIWVCHMVNTLWLRPKRLERHLRAQGLHGDPYKLSLDNSKQTYMLKLQQEAQSKSIGLSKDDAAPRIFSLAHQTVHKYGKNSFAWEGTAPKVIITDPEQIKEVFNKIQDFPKPKLNPIAKYISIGLVQYEGDKWAKHRKIINPAFHLEKLKGMLPAFSHSCHEMISKWKGLLSSDGTCEVDVWPFLQNLTCDVISRTAFGSSYAEGAKIFELLKRQGYALMTARYARIPLWWLLPSTTKRRMKEIERGIRDSLEGIIRKREKALKSGKSTDDDLLGILLQSNHIENKGDENSKSAGMTTQEVMEECKLFYLAGQETTAALLAWTMVLLGKHPEWQARARQEVLQVFGNQNPNFEGLGRLKIVTMILYEVLRLYPPGIYLTRALRKDLKLGNLLLPAGVQVSVPILLIHHDEGIWGNDAKEFNPERFAEGIAKATKGQVCYFPFGWGPRICVGQNFALLEAKIVLSLLLQNFSFELSPTYAHVPTTVLTLQPKHGAPIILHKL
Protein: Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) (Q7K4N3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of Cbp20 and lock the CBC into a high affinity cap-binding state with the cap structure.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Nuclear cap-binding protein subunit 2
- Serrate RNA effector molecule homolog
- THO complex subunit 2
- Negative elongation factor E
- Probable small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein Sm D3
- Small nuclear ribonucleoprotein-associated protein B
- FI21285p1
- Phosphorylated adapter RNA export protein
- LD24793p
Sequence:
MSRRRAHDTEDEGYDHRRNKRRRVSENQEIEDRLESLILRVGERSTSSVESNLEGLVSVLEADLGTFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKMCRWDAARYSLRFLADLVNCHVISATSLLQLLDTMIDVSNEDTVPQVRRDWFVFAVLSTLPWVGRDLYEKKESALESLLLRIEVYLNKRSKKHHNALRVWSSDAPHPQEEYLDCLWAQIRKLRQDNWAEKHIPRPYLVFDSILCEALQHNLPTIVPPPHHDNFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFLIEEHLHHIIETYHHERKDCAAQLLSFPYKHKIPLEYCIVEVVFAELFHMPTPRYLDICYGSILIELCKLQPATLPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLDGEHPRPKFIQEVLQKCLRLSYHQRITEMMPTTYAKLIPLTPVPNYKYANEEAANLPGTTVAHQLVVAIRQKCTPEEVVNILKDIPNSGYSGEEMSDGSFNALKIDVFVQTLLNLGSKSFSHSFAAISKFHSVFRALAETEEAQICILHNIFELWSSHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKLYLWEILHLTIKKMNKHVIKLNTELSEAKEKLAKADSSSSDSEDDSSHKRKKPITHADKPSEEVVERMEEKLEAANVNQKRLFLIVFQRFIMILSEHLLRSDTDGRDPDTDWYRWTIGRLQQVFLMHHEQVQKYSSTLETLLFTSDLDTHILEVFQQFVALRA
Protein: Spermitin, isoform B (Q9VTQ2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLHCQVEGAKAEQRECPVMHSENSAETFSSEESQASDCNQPLDVQSPKLTTNIEESFKVDCKLSLNTLLSPINITDPLRKQIDFQCKLGDLSFFGPVMCSISEFNKEEQTMEPYFIQELDMACAGQEVEQVAEENVFETGPQLKLPENQPINDSITTETNETKLPSTEALNVLNLAEFSEPVMEKSNISIEEVNLTGAEEINEPISDEPNSQLVESAAKLQPKSLGIQIPPLQIEDLISPLVEQPKIATKLGVISFLTGNKLALTPSVRLSFGDRVTTRTNKKSKEIVQQQASKALKALISVFTMQRRLEASQCDNSNNSRSKRFEQLKSSLTFSRVFRQNIFQPTSKIESRQQNTDANSLESGEPNFKSTSAYKEPLPIPYRQDAGEGLTCNGLNVSKDSVFSEVSESDVSETHNKLFAMKKTQEGLSSTRSIGELSNILNNGRVLFSQPVRLFCFNKLKEWKRQGEGQIEVIEHHGSYYIVLHDKVSGELIIHMRVDEKWRIDYMTKSSYSCRWTNINYANCRDGTLERIACSFREPSHAAEFVARIRNSALQSRLECSS
Protein: Pyrroloquinoline quinone transporter (PQQ transporter) (TonB-dependent receptor PqqU) (P76115)
Organism: Escherichia coli (strain K12)
Function: Probable receptor, TonB-dependent.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:32355044}; Multi-pass membrane protein {ECO:0000269|PubMed:32355044}.
Interaction partners:
- Uncharacterized protein YncE
- Hydroxamate siderophore receptor FhuE
- Ferrienterobactin receptor
Sequence:
MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTPAAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIRGIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQQPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQKNLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTIKQTQAGLRYERSLSSRDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQGIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERNLMWNIDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPAGSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNLGLKPSTNDTIEIGSKTRIGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVNASWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEARYMGDIMADDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYEPSPGRNYGVGMNIAWRFE
Protein: Ground-like domain-containing protein (Q22914)
Organism: Caenorhabditis elegans
Interaction partners:
- Ground-like domain-containing protein
- Ground-like domain-containing protein
- Ground-like domain-containing protein
Sequence:
MKSLRIIFCLTLLIASFPAQRSRRKQKFVRLPSGFTFPADAASNFQRDAYIPATFAPPSEKILQAPPRYLTGEHNPAYAHNTDVQGMNYAEYKQAMAPQPHPVDAYSPPPPAPMVPPVTVVEPPAMPYEMTTIASVGPLTTPASVGLKKGNIGGIAQNLNDRYTSLTPEAQRAQKGHTYTALGGGQFYQSLLGGKGGPGGFSPLSFFLNGGLGGTGGGGNNGFFVPVPVVIPPPPPPPPGPNCFTNPSGFLCCNVTLEKTMEDAYLAAKADGASLCNVQKMATAVQAQAEKKFGTTFESVAAHSDFVAKINFAGDLNCKIEIDGKFILAYATPIAEQEVNIVDASSFFSGAADKDLDGVNGTKPTYIVYGPIK
Protein: Extracelullar DNA degradation protein, EddB (Q9HXA4)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Extracelullar DNA degradation protein, EddA
- DNA-specific endonuclease I
Sequence:
MHPLRNAALLGGLALLGLPVANAAELIISEYVEGSGNNKALEFYNSGSQVLDLSAYRVEFYFNGASAAGRSIDLSGSLAPGKTFVLANGVADPALLALASQRVEGSWFNGNDAVLLRRRGGEILDSLGQVGFNPGTTWGSGDVQTLDRSLVRKADIRDGDSDPSDAFDPAAQWLGYPRDTFANLGQHGAGEPGGEEAGLRPIHEVQGAGAESPLVNQRVAIEGVVVGDFQNASELKGFYVQQEDATVDGDPATSEGIFVYDGGNGSDVKLGDRVRVTGQVREFNGLTELVGPLQVSVLASGVALPTPAGISLPLASADALERYEGMRVQLRQTLTVNEVYNLGRYGEVLLSSGGRQMTPTNVVAPGEQAKAMQARNDLDRILLDDGRSGQNPDPIRYPAPELSAYNSLRVGDRTSAIDGVLDYSAGSYRIQPLQTPTFEAANPRPAQPAVEGRLRVASFNVLNYFNGDGKGGGFPTSRGANTAEEFQRQKAKIVAAILASKADIVGLMEIENDGYGEFSAIADLVNGLNASLPQGQRYAFVNPNRAKLGSDEIAVGLIYRGDKVRTYRSAAVLDSSVNPEFDDTRNRPTLAQTFQEINGGERLTIAVNHLKSKGSACDGDPDTGDGQGNCNLTRARAAQALVGWLAGDPTGAKEPDRLIIGDLNSYAKEDPVNVIRSAGYTDLVARQAGAGKGYSYVFSGQSGYLDHALANASLARQVRGAVEWHINADEPRVLDYNVEFKTPRQQDSLYNAEPYRASDHDPVVIGIDLRRVAMKKHRR
Protein: Uncharacterized protein Rv1829 (P9WLR5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- UPF0749 protein Rv1825
- UPF0749 protein Rv1823
- Uncharacterized HTH-type transcriptional regulator Rv1830
- Uncharacterized HTH-type transcriptional regulator Rv1828
- Probable phosphatidylglycerophosphate synthase
- Glycogen accumulation regulator GarA
- Proteasome-associated ATPase
- Elongation factor P
Sequence:
MGEVRVVGIRVEQPQNQPVLLLREANGDRYLPIWIGQSEAAAIALEQQGVEPPRPLTHDLIRDLIAALGHSLKEVRIVDLQEGTFYADLIFDRNIKVSARPSDSVAIALRVGVPIYVEEAVLAQAGLLIPDESDEEATTAVREDEVEKFKEFLDSVSPDDFKAT
Protein: RPW8-like protein 1 (AtHR1) (Q9SCS9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable disease resistance (R) protein.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Exocyst complex component SEC8
- Exocyst complex component SEC6
- Exocyst complex component SEC5B
- Exocyst complex component SEC5A
- Exocyst complex component SEC3B
- Exocyst complex component SEC3A
- Exocyst complex component EXO84B
- Exocyst complex component EXO84A
- Exocyst complex component EXO84C
- Putative F-box/LRR-repeat protein At3g59230
Sequence:
MPLVELLTSAALGLSLQLLHDAIIRAKERSLITRCILDRLDATLHKITPFVIKIDTLTEEVDEPFRKVIEELKRLLEKAIRLVDAYAELKLRNLLRKYRYKRRIKELDSSLRWMIDVDVQVNQWLDIKKLMGKMSEMNTKLDDITRQPMDIIEATGRSSEEDGCTKPTIDIHFRWKNQTKEHEIRFIFK
Protein: Kievitone hydratase (KHase) (EC 4.2.1.95) (Q00870)
Organism: Fusarium solani subsp. phaseoli (Nectria haematococca)
Function: Converts fungitoxic kievitone to the less toxic kievitone hydrate, and thereby protects the pathogenic fungus against this phytoalexin.
Subcellular location: Secreted {ECO:0000269|PubMed:1366757, ECO:0000269|PubMed:7655061}.
Interaction partners:
Sequence:
MMISSVLVAGVVAVSAALASKHPKQYSFKPEDAETIWNGDIPVLYDFGDSQSASYSGSWWTSSYITGTNGEQYLVISHYLDTPVFTYFRASTLNLETLDYNQFITLGNNTANSTTLDVKVGDNGIQSLTADNISQQRAYANDENVTFDITFDATSRVISNAGAGVFQFGPSITYEWGLPNCRTQGSVTDTGGKNITVDPAKSFTWYDRQWGTAAVTSGNWTWFQMHIPETSYKLSVWIIDNDVTNQFSRFATIRGDNDEFQVLPLEWKPIYDRTYQSTAADILYPLDWELDISGFGVFQLSSILDDQEIVGTTAIQTAYEGFVTFNGTVHNKKVQGYGLVEVVYSNWESL
Protein: Flagellar biosynthetic protein FlhB (P35538)
Organism: Bacillus subtilis (strain 168)
Function: May be involved in the export of flagellum proteins.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Flagellar motor switch protein FliM
- Flagellum-specific ATP synthase
- Flagellar biosynthetic protein FliR
- Flagellar biosynthesis protein FlhA
- Flagellar biosynthetic protein FliQ
- Flagellar biosynthetic protein FliP
- FlaA locus uncharacterized protein YlxG
- Flagellar M-ring protein
- Flagellar basal-body rod protein FlgG
- Flagellar biosynthesis protein FlhF
Sequence:
MKLRVDLQFFAGEKTEKATPKKRKDTRKKGQVAKSSDVNTAVSLLVIFLSLIAIGPYMRDRLLSFIETFYTESLTMKLSESNVHTLFVSLLKDMGMILAPILLVALVAGVVSNYMQVGFLFSAEVIQPKLEKLDPIKGFKRIYSMRAIVELIKSILKIVVVGFAAFAVLWLHYGEILRLPLLTPEEALSFVSKLTLWMGLSGAGALLILAGLDYLYQRFDYEKNIKMSKQDIKDEYKKSEGDPIIKSKIKQRQREMAMRRMMQEVPKADVIITNPTHYAIALKYDEEKMDAPYIVAKGVDHLALKIRKIAKEHDVMMVENRPLARALYDQVEIDQAVPEEFFKVLAEILAYVYKTKQKVY
Protein: POU domain class 2-associating factor 2 (Oct coactivator from tuft cells 1) (Protein OCA-T1) (POU class 2 homeobox-associating factor 2) (Q8IXP5)
Organism: Homo sapiens (Human)
Function: Transcriptional coactivator of POU2F3. This complex drives the development of tuft cells, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:36197978}. Nucleus {ECO:0000269|PubMed:35576971, ECO:0000269|PubMed:36197978}. Note=Recruited to chromatin by POU2F3. {ECO:0000269|PubMed:36197978}.
Interaction partners:
- POU class 2 homeobox associating factor 3
Sequence:
MESVPGDYSKRVYQGVRVKHTVKDLLAEKRSGQTSNSRLNGSVSSSQSPFVQMPGSPVTSGYYGVRRSFLSDSDFHNSKQFSNDVYTSSVGKPFPCESSAGQSHAALLEPYFPQEPYGDYRPPALTPNAGSLFSASPLPPLLPPPFPGDPAHFLFRDSWEQTLPDGLSQPDPVSADALLTLPPSTSCLSQLESGSIAQHRGSSWGSSLAGAQSYSLHALEDLHHTPGYPTPPPYPFTPFMTVSNDLPPKVGPLSPDEEADTGSLHDPSPWVKEDGSIAWGSYECRRAY
Protein: Straightjacket, isoform D (A0A0B4K7P4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAWSRLLAWWRLCLGLLSVLVCLAPCVNLQPAENINYNLVHSWADKLGMELFHLGDFITRRKEVQESFKDAKVVSRNGASIVDSMAKEIEMMMDLKVSAVRRIMDTAENTALSHQNDMADKMFSYYSAKEMLEPGDPVPPIPTPAPDMDKDIGEPLIYVQPKVVVLEPRPEFHNTPVNFSVSSVHVPVNVFDRAPDVIKAIQWSENLDQIFRDNYKNDPTLSWQFFGSSTGFMRQFPASKWRKDVPVDLYDCRLRSWYMEAATSPKDIVILMDGSGSMLGQRLDIAKHVVNTILDTLGTNDFVNIFTFDKEVSPVVPCFEDTLIQANLGNIRELKEGIELFRPKSIANYTAALTKAFELLEETKLSSRGAQCNQAIMIIGDGAPENNREVFELHNWRDPPYKPVRVFTYLIGKEVANWDDIRWMACENQGYYVHLSDTAEVREMVLNYIPVMARPLVLGRHDHPVIWSQVYADIEDTKLSDYLWDINQCEYQKADVLEYWQVHDRMLEPSEMHRRKYRRMKETWNQPVDSNVYQFMTTVSMPIYDRRENANITEEVLINEALWELQTRETRIANILGVAGTDVPINEIKKLLSPFTLGVNGYAFIVTNNGYVLFHPDFRPIFQGYILKPAYNSVDMIEVELLDDDRPARDFNPVLMTIRDSIINQSTGSKWMLVKNHFDEMKRVARVKRQYYWTAIKKTPFTLVISYPEQYGVSHMDIRADQEIHRISIKGTNLRSVFSGKRWKIHPDWLFCKHSNRTFKTPEIELLYFLERMSEPGWRWPGSRSAMPPEHAAAMFCDRQLMQALVFDARVTGWFSNNTSFNSKDDKGNEFKQRFGVTVAFLATHSGLTRWHEFHSNAAEESGVGETFSQNNTRAIDEIWYKRAVDQHFVREESFVYSVPFDAGESNSEILVTASHAVFHNEGGKTAPAAVVGFQFQHSALYKLFHNITGNACAVDDKDCYILDNNGYVIISTRVHETGRFFGEVNGAIMKRLLEENVYRQVTVYDYQAVCFESKNDNNASSMLLSPLFHLLRVGKWLLHTALWYIVQLLQWAPGVSSHYADMYGDSNDTEPPPPEPHPDHHARNGNGHGKKDDDHWLRYLTLHRTRLKPCDMKRDLYTLFNEKDNVVYNMTAHACERPFVVLPIPFSNLILLVIDQLCPRDGSVVLTVNPQPIDYHLSVNDSLACYKQAREFNRMRPHSCISRHANESGIKLCGKACSVYANLGLLLLCHILSRWL
Protein: Protein E5 (P0CK45)
Organism: Bovine papillomavirus type 1
Function: E5 can induce cellular DNA synthesis. It seems to interact with a 16 kDa cellular protein. E5 seems to activate the PDGF receptor.
Subcellular location: Host membrane; Peripheral membrane protein.
Interaction partners:
Sequence:
MPNLWFLLFLGLVAAMQLLLLLFLLLFFLVYWDHFECSCTGLPF
Protein: RanBP2-type domain-containing protein (Q38DM6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRPPTLRAFTSPHVIRHRITTLAVSGTKLNQRLSLLLGVGLPECTATEGLASSLRFVSQECLPPYLAFTFLSHCWSMWSASSSFAVAARKTVGGTNDSVALETLLNVSEECLLAYSRIAGEENRSQRQIVNDRGTVKNATMGASTPLPHSRAGYHYIVDHMLRICSGYMDARTAVTLLQYAVRVEDSEGAVFKGLVELLASRTSGDPLLFENCLRKVLGVALPVHVSPIVTSVLCLRVVTSSVLKLCMHHVATVVRGRQSGRLAVENALGGLHRCAVMALHWLLKNPCGDQWCNELCIQVMSCLKYAPMFLLCDVYGTMADRGLVTPSVQCKFLANCGVALGSSGSVPDHCGEVIIRAFTELTKSDRETRYIEEGLVHGSAALVALGKGGLVRRAYVMFPTLRVTHHLVMAHVHHADVVRACDSLLSVACSREEGWINIPPPVMHAIHAVCVLVGRSGSSADVVPLYRAIVCFHNPGIIVSQCMEYVLSGLCDRVARINGHFSKETQPCTILEHIVPLLRAIVRCIGDDINTDMILELLETALSVEYFSVPLTASIVWTFQRSTSLALKDLFSRVDPSTNGVPFLNYYALCHARDRGMLETVEHLATVWHCDVEPILKRYTFLLPSYKLWKCAACGRFNSDRFNYCLCSALRNGFVVCSKCAYAQDERLSFCQSCGVRTEEGAVAAAVVRRAWTCGECGANNPARQVSSCFRCKADLGPVAKALKEMGNSKVTSCSCPTVDSSGEGKGSCRSMHYCRHCGWMREPWAVANSTVWRCEGCSQLRSSLDRTCPECPHVDFLPFAMAHKSSDVRSCVDCGAMAENPFAEKCALCAGALRVGATALKAPTTSSAAVGESELMVETAQWCSNCGGIVVEKLSSHCSECGHALHFADVLHLAVRRCSACGEDLGTQQIGVVCVHCFSFAPPVPREGWSTAVVHETFRVIDRAMERKLGCDTLADLFHKILVSFRQHVGQATISETRVAVAVALGRLQAVLIASVPYERMARRVIALTKQLLEHVDNVCGVSSSHFHPGQCPHCLGTHRPELCSFNEEEWVCEVCGAENENGDVCRYVCRNCLSLRDTVRELCPTEAWECPQCQRANVDFESYCIFCGVQRAVVEDAVEEAAEVVPFIPAKCSECNLVHLEARCPLCHNTIPETLRKAEGVVCLVTSRYAFIQPVGTEHPNQRVYVGQQWLRKHKWTGGEKVTFTARLNDQGGFRVTSVHS
Protein: Insecticidal crystal toxin domain-containing protein (F4HQT8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized protein
- Phosphoglycerate mutase family protein
- Receptor-like protein 43
- Protein LURP-one-related 2
- Copper ion binding protein
- Receptor-like protein 53
- Berberine bridge enzyme-like 6
- Cysteine-rich receptor-like protein kinase 6
- UDP-glycosyltransferase 76C5
- Receptor-like protein kinase At5g59670
Sequence:
MYVTRRLSEYQRNRSELPESPNSGVLIIQDEESRPTCCFGSCYRATLKGLPFPQNANLIVSESRIFLNQTITYIDPVVFIPVLDQPLSSNRYYVIKRGGKHSGKASANAKEEDRVPCCFCFSYVPEAKPQEADPNDIYQQFQIHQKRSSSRYYTATSVAPNGKPPEFLKRKYWNAEYSTSEDFGLKDDAKGIYTEIRSELPSDFNTSVVVGKWYVPFIFVKEGNAKDQLKSSAYYSMILLQRWEEVYSCENAYNENREVVVDVEVEPEVVKLEGQEIGKNTKRVDENGVFWFAVAEKRIGLRSVVMERMKWEEERFGWKIEPQRAVVKKSERFNGGGSNWKSYRCYVLVESFELRRKDKSLVLTFEFKHVDKLRTKWES
Protein: F20P5.23 protein (O04541)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00810}.
Interaction partners:
Sequence:
MKHLPVVSFKTMVANKKLTTTDALDFLHLVKTKYQDNREIYDSFLTIMKDFRGQRAKTCDVISKVKELFKGQPELLLGFNTFLPTGFEITLSDDELTSNSKFAHFDEAYEFVNKVKTRFQNNDVFNSFLEVLKTHKKENKSVAELYQEVAILFQGHRDLLEEFHLFLPHYG
Protein: Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Q6DID7)
Organism: Mus musculus (Mouse)
Function: Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Also plays an important role in establishment of the anterior-posterior body axis formation during development.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:19841259}; Multi-pass membrane protein {ECO:0000269|PubMed:19841259}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:19841259}; Multi-pass membrane protein {ECO:0000269|PubMed:19841259}. Cell membrane {ECO:0000250|UniProtKB:Q5T9L3}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q5T9L3}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q5T9L3}; Multi-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000250|UniProtKB:Q5T9L3}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Proto-oncogene Wnt-3
- Protein Wnt-5a
- Protein Wnt-8a
- Protein Wnt-3a
- Sorting nexin-3
- Proto-oncogene Wnt-1
- Protein Wnt-4
- Protein Wnt-11
- Protein Wnt-7b
- Protein Wnt-2b
Sequence:
MAGAIIENMSTKKLCIVGGILLVFQIVAFLVGGLIAPAPTTAVPYTAIKCVDVRKNHHKTRWLAPWGPNKCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEISMDVSLGYRDDMFSEWTEMAHERVPRKLKCTFTSPKTPEHEGRYYNCDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVSEGHWKWGGVTVQVSSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE