wanglab/gogpt-training-data huggingface dataset:
Protein: DENN domain-containing protein 10 (Protein FAM45A) (Q8TCE6)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B. Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form.
Subcellular location: Late endosome {ECO:0000269|PubMed:30771381}.
Interaction partners:
- Vacuolar protein sorting-associated protein 29
- Late secretory pathway protein AVL9 homolog
- Coiled-coil domain-containing protein 22
- DENN domain-containing protein 11
- Protein DENND6A
- Vacuolar protein sorting-associated protein 26C
- COMM domain-containing protein 1
- VPS35 endosomal protein-sorting factor-like
- Coiled-coil domain-containing protein 93
- COMM domain-containing protein 3
Sequence:
MAAAEVADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESHVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI
Protein: Lipopolysaccharide binding protein (O97363)
Organism: Bombyx mori (Silk moth)
Interaction partners:
Sequence:
MKAALASLVFVLTIAYLDGQQFRYDYTYMRDINGWLKLQEIPATWQEARLRCHLEGSLLASPLDDALKSGMLSLIKNKKTSCGIFTGIHATFSKGDYRSVEGVPLAKIPHDWADYEPDNAGGDENCILMNPDGNFADVNCTETFQYVCYKKKTATLAMASCGSVDSEYVLSKDTGNCYKFHKVPRTWSRAYMACSAEGGYLTIINNEKEATFLRDLFAKNPAGQMIGSFWKDVAFIGFHDWNERGEWLTINGEKLQEAGYEKWSGGEPSNATTGEYCGSIYRSALLNDLWCEKPAPFICEKEPRSLLREHDDK
Protein: Oxysterol-binding protein-related protein 3A (OSBP-related protein 3A) (Protein UNFERTILIZED EMBRYO SAC 18) (Q9LZM1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Oxysterol-binding protein that may be involved in the transport of sterols between the ER and the Golgi. Binds beta-sitosterol. Required for ovule fertilization.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:19207211}. Golgi apparatus {ECO:0000269|PubMed:19207211}. Note=Interaction with PVA12 is necessary for targeting to the ER. Located in the Golgi in the absence of interaction with PVA12.
Interaction partners:
- Vesicle-associated protein 1-2
- Vesicle-associated protein 1-1
- Syntaxin-81
- Threonine--tRNA ligase, mitochondrial 1
Sequence:
MASNDPKNGGGFFASLASSITNFGSAMSKSVNGLMGYEGLEVINPEGSTDDAEEEAGRGRWKQEERDGYWKMMQKYIGSDVTSMVTLPVIIFEPMTMLQKMAELMEYSYLLDMADKTEDPYMRMVYASSWAISVYYAYQRTWKPFNPILGETYEMTNHNGINFIAEQVCHHPPMSAGHAENEHFAYDCTSKLKTKFLGNSIDVYPVGRTRVTLKRDGVVLDLVPPLTKVHNLIFGRTWVDSPGEMVMTNLTTGDKVVLYFQPCGWFGSGRYEVDGYVYNSAEEPKMLMTGKWNESLSYQPCDAEGEPLPGTELKEVWKVAEAPKNDKYQYTHFAHKINSFDTAPKKLLSSDSRLRPDRYALEMGDMSKSGFEKSSLEDRQRAEKKSREEKGQKFAPKWFDETEEVTPTPWGDLEVYQFNGKYSVHRATAENSEDTTDVKLTQFNPWQFQDLSA
Protein: Centrosomin's beautiful sister, isoform B (A0A0B4K775)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFATLKNKIKEETGDDVVQSANQRYPGNNNNNYRLRSRRVSINSNSADDVGGGGFYNESEQLCELRSQCNELTTKLSTVTQGLQQLQEEKTRVDKTNEILLESVRVAQTQKDIYCEEQEKIQNLQQIEIDKLKNLLSFREQESVDRMGLMRQQTQQIESLSEELERLRPIESVAEDLRDELEQLRHSTQQEKNLLTTTLAAVQEENRHLKKRMKIVEESRLESLGKLNSEQQVQALIREHKLLEQHLEEAHLQLSDIKGSWSGQNLALETQVSRLSKQVAEETTEKRKALKSRDDAIESRKQVSFELEKAKDEIKQRDDKVKLLEEEIDELSVALKECREENEQQVLFERNKSQNLETEVKDLKTRLTAADDRFSEYSSNAEQVAQKLRVQVTEKQEQLDETIMQLEIEREEKMTAILRNAEIAQSEDILRQQLRLERSEASDLQERNNQLVRDISEARQTLQQVSSTAQDNADKLTEFERVQLEIIEKNKTIKTLNQRLIDLKKTVQKELRSAQISTDSESHPTTTPGHRISSSSLEAFSTGDKGNCVIMDEVNFQYLKHVIVEARHLVRAVSTLLQLTTEEEKLLHDTLNWKMSWFGMKPT
Protein: LHFPL tetraspan subfamily member 5b (Zgc:171589 protein) (A8KB64)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLPAQEAAKIYHTNYVRNSRAIGVMWAVFTLFFAIITVVVFIQPYWIGDSVNTPQAGYFGLFRYCIGNPITSELVCKGSVFDFGSIPSGAFRTALFFVGTSMLLIVGTIVCLGLFFFCNAASVYKICAWMQTSSAVLMVMGCMIYPDGWDSAEVKRMCGERTTKYNLGNCTIRWAYILGIISILDAGLLALLAFTLGNRQDKLLPDDFEVEGENNA
Protein: 6-phosphogluconolactonase-like protein 1 (P50278)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in regulation of tRNA subcellular distribution.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Glucose-6-phosphate 1-dehydrogenase
- Probable gluconokinase
- Exportin-T
- 6-phosphogluconate dehydrogenase, decarboxylating 1
- 6-phosphogluconate dehydrogenase, decarboxylating 2
- Bifunctional purine biosynthesis protein ADE16
- 6-phosphogluconolactonase-like protein 2
- Bifunctional purine biosynthesis protein ADE17
- Serine/threonine-protein phosphatase 1 regulatory subunit GAC1
Sequence:
MTTTVPKVFAFHEFAGVAEAVADHVIHAQNSALKKGKVSRSTQMSGTSLNGNGNTESKTMERVNSVRSNASSRGGSEDGATKKLKKEKERRFKIALSGGSLIQVLHEGLLKRDDVQWGKWDIYFADERLVPFSSSESNYGLAKRKIFDLIDTEKYGTPKIYHIDESLINDPQECADNYEKILIKGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQENLRENLAWVIPVENAPSGPSNRISLTIPVICHSHRVTFVVEGATKAPVIKTIMERPEKGLPSSIVNEGAAGRVSWFVDDDALKDVFVIKKKYKFYDDENLTE
Protein: Tubulin polyglutamylase ttll-4 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 4) (Q09647)
Organism: Caenorhabditis elegans
Function: Monoglutamylase which modifies tubulin, adding a single glutamate on the gamma-carboxyl group of specific glutamate residues of target proteins. Involved in the side-chain initiation step of the polyglutamylation reaction but not in the elongation step. Preferentially modifies beta-tail tubulin over the alpha-tubulin. Involved in side-chain glutamylation of tubulin in sensory cilia. Together with ttll-5 and ttll-11, required for male mating.
Interaction partners:
- Cytosolic carboxypeptidase 1
- Cytosolic carboxypeptidase 6
- Kinesin-like protein
- Alpha-tubulin N-acetyltransferase 1
- Kinesin-associated protein
- Kinesin-like protein
- Spastin homolog
- Tubulin polyglutamylase ttll-5
- Osmotic avoidance abnormal protein 3
Sequence:
MSSGYSSAPSVSHTSSDTDLNRIDSYDDGAEETTDEQRMCGLSELVTSCLTSSRLKAIDEEDEEENCNDIEIVGLSKTTTKVKRSKKVLSCPIVSSSTKKENGNAAPFLKSSQFTDVPPTIRFYTKGTKVTKPARKIQARLTWCHNSLLPIVMRQTLAASHFTVVDESLFYVGYWGRHLKSAQYRALQPHQKVNHFPGAFHIGRKDRLWMHIRKQQERFEGEFDIMPFTYILPTDRQELLKYLETDASRHVIVKPPASARGTGISVTRKPKDFPTTATLVAQHYIERPLTINRAKFDLRLYAYVPTFEPLRVYIYDQGLVRFASVPYSHSVSTISNKYMHLTNYSINKLAEADGVANKPVPKWTLHHLWEHFDEMGVDREKIQREIEEVIIKAFISTEKPIREHMSRFLEQEFICYELFGIDIILDEDYKPWLLEVNISPSLHSGTPLDVSVKAPLAKDVLNLAGVYVPPSFDKLSDADYSTRPRNGRKNREQLIKEASWVAAYKDQLGVIDNRIFKRLTPEDTRALVEFEDELERIGDFKLVFPTAHTSHYQKYFAETIYMNILLQQWQIAQEDDRSIGINRLEQLCRQKHMQSDQETSF
Protein: Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) (P49641)
Organism: Homo sapiens (Human)
Function: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Alpha-
- Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Alpha-mannosidase 2
- GDP-fucose transporter 1
- Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA
- Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
- Nucleotide sugar transporter SLC35D2
- Beta-1,4-galactosyltransferase 1
- Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
Sequence:
MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFALGGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPMEIATFRLRLG
Protein: GINS subunit domain-containing protein (Q38F51)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- DNA helicase
- GINS subunit domain-containing protein
- Cell division cycle 45
- DNA replication licensing factor MCM3
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM5
- DNA replication complex GINS protein SLD5
- Uncharacterized protein
- DNA polymerase II subunit 2
- Uncharacterized protein
Sequence:
MADVADPSSELINELRALVVSGSGLVPLDERKVHTVVENMTDAFRHLESISRNPFADPSQPYYSGAMRFYKAKCLRDKRCVVAYLLWRQSQITKSWWEARDNTISNMLAPCERTFLQDYNDVMVEYMTSFAVPLDLRSFTWRPPSTQQLEVRGLVNHVFVSSITGAVINLYKGKQILLGFEEAESLIQQGVVELVE
Protein: Carbonic anhydrase 14 (A0A8I6A8W4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
VWTNVHGNLPPPGPHGQDHWPASYPECGGNAQSPIDIQTDGVIFDPDLPTVQPHGYDQLGTEPLDLHNNGHTVQLSLPPTLHLGGLPRKYTAAQLHLHWGQKGTLKGSEHQINSEATAAELHVVHYDSESYGSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSHLHEVRYKDQKTSVPPFNVRELLPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEEDPSEPLVQNYRVPQPLNQRTIFASFIQVGPLYTTGEMLGLGMGISAGCLCLLLTIYFIAQKIRRKRLGNRKSVVFTSARATTEA
Protein: Transcription factor SOX-10 (O55170)
Organism: Rattus norvegicus (Rat)
Function: Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). Transcriptional activator of MBP, via binding to the gene promoter.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q04888}. Nucleus {ECO:0000269|PubMed:9412504}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q04888}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q04888}; Cytoplasmic side {ECO:0000250|UniProtKB:Q04888}.
Interaction partners:
- E3 SUMO-protein ligase EGR2
- Paired box 3
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- Oligodendrocyte transcription factor 1
- Oligodendrocyte transcription factor 2
- Myelin regulatory factor
- Myelin proteolipid protein
- Myelin basic protein
- Platelet-derived growth factor receptor alpha
- Transcription factor HES-5
Sequence:
MAEEQDLSEVELSPVGSEEPRCLSPSSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGETDQGGAAAIQAHYKSAHLDHRHPEEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSLGEGGKPHIDFGNVDIGEISHEVMSNMETFDVTELDQYLPPNGHPGHVGSYSAAGYGLSSALAVASGHSAWISKPPGVALPTVSPPAVDAKAQVKTETTGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHAGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
Protein: Probable protein phosphatase 2C 62 (AtPP2C62) (EC 3.1.3.16) (Q93V88)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable protein phosphatase 2C 52
- Probable protein phosphatase 2C 2
- Probable protein phosphatase 2C 14
- phosphoglucomutase
- Dirigent protein 20
- Phosphoglucan phosphatase LSF2, chloroplastic
- Probable protein phosphatase 2C 66
- Protein phosphatase 2C 29
- Phosphoglucan phosphatase DSP4, chloroplastic
Sequence:
MADHLILSLQAPPFLIFPCSLHRSWRFPGGIRYSVPEFRLSSQLQLANSISPSKSSASSSSPPENSAPEKFDLVSSTQLKDGSHVFRFGDASEIEKYLEAEEKARCVEVETQNAKIAEEASEVSRKQKKLVSSIIETSTEKEETAAPSDLSNVIKIKDRKRVRSPTKKKKETVNVSRSEDKIDAKSASVSNLSSIVSVAEAIPISSTEEEAVVEKEITAKSYNVEPLSSEAMKKVSVNKIGDCETNGYQENRMEVQARPSLSTQQEITPVSTIEIDDNLDVTEKPIEAEENLVAEPTATDDLSPDELLSTSEATHRSVDEIAQKPVIDTSEENLLNTFEAEENPVVEPTATAAVSSDELISTSEATRHSVDEIAQKPIIDTSEKNPMETFVEPEAVHSSVDESTEKLVVVTSDVENDGENVASTTEDEITVRDTITDSGSISNNDDTKVEDLQLPVPETASLEPIKAASGREELVSKAFYLDSGFASLQSPFKALAGREDAYFISHHNWIGIADGVSQWSFEGINKGMYAQELMSNCEKIISNETAKISDPVQVLHRSVNETKSSGSSTALIAHLDNNELHIANIGDSGFMVIRDGTVLQNSSPMFHHFCFPLHITQGCDVLKLAEVYHVNLEEGDVVIAATDGLFDNLYEKEIVSIVCGSLKQSLEPQKIAELVAAKAQEVGRSKTERTPFADAAKEEGYNGHKGGKLDAVTVIISFVKIVST
Protein: Homeobox expressed in ES cells 1-B (Homeobox protein ANF-1) (XANF-1) (Xanf1) (Q91898)
Organism: Xenopus laevis (African clawed frog)
Function: Regulates the earliest stages of development of the anterior neural plate. Plays a role in forebrain development by inhibiting the expression of otx2 and pax6 in the rostral region of the anterior neural plate. Necessary for both neural differentiation and neural patterning. Controls Spemann organizer development. May act as a transcriptional repressor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:18297730}. Note=Enters the cytoplasm in the presence of zyx.
Interaction partners:
Sequence:
MSPALQKGSSLMENRSPPSSFSIEHILGLDKKTDVASSPIIKHHRPWIECSSKGVVNGTCWQIPVIACDLPIQVHAVHRSEEEETKIRLEKCFGDEDRLTYKRELSWYRGRRPRTAFTRSQIEILENVFRVNSYPGIDVREELASKLALDEDRIQIWFQNRRAKLKRSHRESQFLIVKDSLSSKIQE
Protein: Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP) (Q15582)
Organism: Homo sapiens (Human)
Function: Plays a role in cell adhesion. May play a role in cell-collagen interactions (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:18450759, ECO:0000269|PubMed:26273833, ECO:0000269|PubMed:8024701}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:8077289}. Note=May be associated both with microfibrils and with the cell surface (PubMed:8077289). {ECO:0000269|PubMed:8077289}.
Interaction partners:
- Fibronectin
- Homeobox protein TGIF2
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Homeobox protein TGIF2LY
- Homeobox protein TGIF2LX
- Biglycan
- Decorin
- Integrin beta-3
- Matrix metalloproteinase-9
- Collagen alpha-2
Sequence:
MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIAAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAFSRASQRSVRLAPVYQKLLERMKH
Protein: Phosphoglucan phosphatase LSF2, chloroplastic (EC 3.1.3.-) (Phosphoglucan phosphatase like sex Four2) (Protein LIKE SEX4 2) (Q9SRK5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Starch-associated phosphoglucan phosphatase that selectively dephosphorylates the glucan C3 position. Probably participates in the regulation of starch degradation.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:22100529}.
Interaction partners:
- Isoamylase 3, chloroplastic
- Phosphoglucan phosphatase
- Maltose excess protein 1, chloroplastic
- Protein PTST, chloroplastic
- 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic
- Alpha-glucan water dikinase 1, chloroplastic
- Phosphoglucan, water dikinase, chloroplastic
- Beta-amylase 1, chloroplastic
- Beta-amylase 3, chloroplastic
- 4-alpha-glucanotransferase DPE2
Sequence:
MSVIGSKSCIFSVARYTRENEKSSCFTSINKKSSLDLRFPRNLAGVSCKFSGENPGTNGVSLSSKNKMEDYNTAMKRLMRSPYEYHHDLGMNYTLIRDELIVGSQPQKPEDIDHLKQEQNVAYILNLQQDKDIEYWGIDLDSIVRRCKELGIRHMRRPAKDFDPLSLRSQLPKAVSSLEWAVSEGKGRVYVHCSAGLGRAPGVSIAYMYWFCDMNLNTAYDTLVSKRPCGPNKGAIRGATYDLAKNDPWKEPFESLPENAFEDIADWERKLIQERVRALRGT
Protein: Late embryogenesis abundant protein 19 (OsLEA19) (Late embryogenesis abundant protein, group 3) (LEA-3) (OsLEA3-1) (A2Y720)
Organism: Oryza sativa subsp. indica (Rice)
Function: Involved in response to drought stress.
Interaction partners:
Sequence:
MASHQDQASYRAGETKAHTEEKAGQVMGASKDKASEAKDRASEAAGHAAGKGQDTKEATKEKAQAAKERASETAQAAKDKTSGTAQAARDKAAESKDQTGGFLGEKTEQAKQKAAETAGAAKQKTAETAQYTKDSAIAGKDKTGSVLQQASEQVKSTVVGAKDAVMSTLGMTEDKAGTDDGANKDTSATAAATETTARDH
Protein: Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) (Q8TD30)
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.
Interaction partners:
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase, mitochondrial
- Putative aspartate aminotransferase, cytoplasmic 2
- Glutamate dehydrogenase 1, mitochondrial
- Alanine--glyoxylate aminotransferase
- Glutamate dehydrogenase 2, mitochondrial
- N-acetylglutamate synthase, mitochondrial
- Alanine--glyoxylate aminotransferase 2, mitochondrial
- Alanine aminotransferase 1
- Fumarate hydratase, mitochondrial
Sequence:
MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA
Protein: Protein transport protein Sec31, putative (Q385F2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
- ADP-ribosylation factor, putative
- Protein transport protein SEC23
- Protein transport protein Sec13, putative
- Protein transport protein Sec24C, putative
- Protein transport protein sec13, putative
- Protein transport protein SEC23
- Protein transport protein Sec24A, putative
- Sec16 Sec23-binding domain-containing protein
- Vesicle-associated membrane protein, putative
- Syntaxin 5
Sequence:
MRLKATPLTCVFAWAPEVLGTPTFLAAASVAGAIDDNFSGEAFLEIRLVDVTQTDETEMPVLGRTVIPAHALRVDWSPHGGERGIIAVSCEDGAVYVYDASIMMKNYGINPDRNTEEPRLSVIAEHRGAVRGCQFNPSQPTFLAIGGDDGAWDVWMLENPREPQRVPIMPDSAQPAGITHLQWNPKWPHILATSVANGVVNVWNLKTQTLAVSLHVSKSGKSGSSGNIIAWHPSMATQIAVGLDEKHPAIQIWDLKKAMMPLREMLGHENAVTGLAWNMTDHAILASCDADGKTLWWDPSTGERNGALQQQNGYMVDMKWSRALPVVLATSSFEPLFCVSTAEDVSSAPAPGASVQKSLQRPCGASIGISGLVASVSSHSANAVRLTRIVTNNASDPSGMSGGDPVAEISRLPPASVERVEWLKAHQYPLLAAAAACKNDRTPILSYLAEDAPTEDTEDPFETMQGTQKSLEDIAASHVAAGRINEAVEACLDECEFGDAFAIAYLQGGKLMQRVQQEYTRHILMNSQGKRHIVYASAVAAGDFRSLMVGGNALWKEALSVIISFVGERFSEACDKLALALKEAGNRESAMTCFICSGNVDAVAELWHEENMPVEKLVQEVLLLEEVTGRKVTSTFFGDYLYEYGLGLLGKGLLTKAMPIFQRSANVGNRNAAIMVDRMRFEVPCGQITFPFVATPLSDSLSQSCLEFLANKGNGQQQQQQQQPPSAVQPQYQQQRMGATMPPPTQQQQQQQPPSAVQPNMYGGQQQQPPSVVQPQYQQQRMGATMPPPTQQQQQQQPPSAVQPNMYGGQQQQPPSAVQPNMYGGQQQQAPAPGIIAQQPGPAVTANSAAPVPRLMPHPISSWSSLGSVGGGVVTNHPPATATMSGYCGAPPQNLPSQELQGPVPTSAPPRPPNHMDPQRSMPMIPPPSCGSSVTSVQGLHAPAQPTVVPSLPSQQVIGTPLAPPQQFPTPAQPPSGPRGMPLPPRAPSGLDTNPTSTFGAPPTGSLHRTGKSSPSPEPSAPRVGNMMVAPPGSAPPSMTSGGLPPPRMPSDGSNANWNMNPQSVTNQPPQAASMTAPSSVAPPPPGIPSTAVGTAPPVVTAPRVGGVAYAPVANPGAPPRFAAAGGRPADDFGLSSFEISSLNPEHRDLAQKLRTTIQQVANAQRRSAIAKAAMELFQALQTGSLPPDVVGLLSEYINCLGSQRSREMWKELATKHFSAIQHINNLKFLQ
Protein: Kelch-like protein 11 (Q9NVR0)
Organism: Homo sapiens (Human)
Function: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.
Interaction partners:
- Cullin-3
Sequence:
MAAAAVAAAAAAAAAASLQVLEMESMETAAAGSAGLAAEVRGSGTVDFGPGPGISAMEASGGDPGPEAEDFECSSHCSELSWRQNEQRRQGLFCDITLCFGGAGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKAADMIRRNFHKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVADAVERHALRAENIQSGTCQHPTSHVSLLPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAIEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYCLENEEAVRKIASQVSDEILESLPPEVLSIEGAAICYYKDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC
Protein: LRR receptor-like serine/threonine-protein kinase ER1 (EC 2.7.11.1) (ERECTA homolog 1) (ER homolog 1) (OsER1) (Receptor-like cytoplasmic kinase 204) (OsRLCK204) (Q69SP5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Receptor kinase involved in the regulation of thermotolerance. Functions as positive regulator of heat tolerance. May be involved in the regulation of cell proliferation and cell growth.
Subcellular location: Cell membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Epidermal patterning factor-like protein
- Epidermal patterning factor-like protein
- mitogen-activated protein kinase kinase kinase
- mitogen-activated protein kinase kinase kinase
- LRR receptor-like serine/threonine-protein kinase SIK1
- Os01g0623000 protein
Sequence:
MTPAPAAASYRALVALLLVAVAVADDGSTLLEIKKSFRNVDNVLYDWAGGDYCSWRGVLCDNVTFAVAALNLSGLNLGGEISPAVGRLKGIVSIDLKSNGLSGQIPDEIGDCSSLKTLDLSFNSLDGDIPFSVSKLKHIESLILKNNQLIGVIPSTLSQLPNLKILDLAQNKLSGEIPRLIYWNEVLQYLGLRGNNLEGSISPDICQLTGLWYFDVKNNSLTGPIPETIGNCTSFQVLDLSYNKLSGSIPFNIGFLQVATLSLQGNMFTGPIPSVIGLMQALAVLDLSYNQLSGPIPSILGNLTYTEKLYMQGNKLTGPIPPELGNMSTLHYLELNDNQLSGFIPPEFGKLTGLFDLNLANNNFEGPIPDNISSCVNLNSFNAYGNRLNGTIPPSLHKLESMTYLNLSSNFLSGSIPIELSRINNLDTLDLSCNMITGPIPSTIGSLEHLLRLNLSNNGLVGFIPAEIGNLRSIMEIDMSNNHLGGLIPQELGMLQNLMLLNLKNNNITGDVSSLMNCFSLNILNVSYNNLAGVVPTDNNFSRFSPDSFLGNPGLCGYWLGSSCRSSGHQQKPLISKAAILGIAVGGLVILLMILVAVCRPHSPPVFKDVSVSKPVSNVPPKLVILHMNLSLLVYEDIMTMTENLSEKYIIGYGASSTVYKCVSKNRKPVAVKKLYAHYPQSFKEFETELETVGSIKHRNLVSLQGYSLSPVGNLLFYDYMENGSLWDVLHEGPTKKKKLDWETRLRIALGAAQGLAYLHHDCSPRIIHRDVKSKNILLDKDYEAHLTDFGIAKSLCVSKTHTSTYVMGTIGYIDPEYARTSRLNEKSDVYSYGIVLLELLTGKKPVDNECNLHHLILSKTANNAVMETVDPDIADTCKDLGEVKKVFQLALLCTKRQPSDRPTMHEVVRVLDCLVRPDPPPKSAQQLAMPQRPAVPSYINEYVSLRGTSVLSCANSSCTSDAELFLKFGEVISQNTE
Protein: 2-dehydropantoate 2-reductase (EC 1.1.1.169) (Ketopantoate reductase) (KPR) (P9WIL1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P0A9J4}.
Interaction partners:
- Pantothenate synthetase
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- Uncharacterized protein Rv2575
- Aspartate--tRNA
- Uncharacterized protein Rv2574
- Dephospho-CoA kinase
Sequence:
MATGIALVGPGAVGTTVAALLHKAGYSPLLCGHTPRAGIELRRDGADPIVVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQPHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAAASDGPG