wanglab/gogpt-training-data huggingface dataset:
Protein: Spermatogenesis-associated protein 31A7 (Protein FAM75A7) (Q8IWB4)
Organism: Homo sapiens (Human)
Function: May play a role in spermatogenesis.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Spermatogenesis-associated protein 32
- Proton-coupled amino acid transporter 3
Sequence:
MENLPFPLKLLSASSLNAPSSTPWVLDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSPGKRKCPVGRRRRPRGRMKNHSLRAGRECPRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEPMEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVPQSLSPHEDLVASVPAISGLGGSNSHVSASSRWQETARTSCAFNSSVQQDHLSRHPPETCQMEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEKENVGSFTNRMTPEKHLNYLRNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERDPCPHLGQILGETPQNLSRDMKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVCVRRSWLAVNQALPVSNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSEVEVDMFLRKPPMASLRKQVLTKASDHMPESLLASSPAWKQFQRAPRGIPSWNDHEPLKPPPAGQEGRWPSKPLTYSLTGSIQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDVHGFEAPGTSKSSLHPRVSVSQDPRKLCLMEEVVNEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVHEEPRNPNCQGSCKSQRPMFPPIHKSEKSRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKKQPPSVSPFGENIKQIFQWIFSKKKSKPAPVTAESQKTVKNRSRVYSSSAEAQGLMTAVGQMLDEKMSLCHARHASKVNQHKQKFQAPVCGFPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQIRNQQPLKSVRCNNEQWGLRHPQILHPKKAVSPVSPPQHWPKTSGASSHHHHCPRHCLLWEGI
Protein: Uncharacterized oxidoreductase Rv1543 (EC 1.-.-.-) (P9WGS1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible ketoacyl reductase
- Probable diacyglycerol O-acyltransferase tgs2
- Putative diacyglycerol O-acyltransferase Rv3480c
- Putative diacyglycerol O-acyltransferase Rv0895
- Putative diacyglycerol O-acyltransferase Rv2285
- Putative diacyglycerol O-acyltransferase Rv1760
- Putative diacyglycerol O-acyltransferase Rv2484c
- Uncharacterized protein Rv1546
- Probable diacyglycerol O-acyltransferase Tgs4
- Putative diacyglycerol O-acyltransferase Rv1425
Sequence:
MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALVRTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVRNRAFNMFGDSSAAKGSESQTDTSELDKRSETFVRATRGIHW
Protein: Peptidylglycine alpha-hydroxylating monooxygenase (dPHM) (EC 1.14.17.3) (O01404)
Organism: Drosophila melanogaster (Fruit fly)
Function: Monooxygenase that catalyzes an essential reaction in C-terminal alpha-amidation of peptides. Produces an unstable peptidyl(2-hydroxyglycine) intermediate. C-terminal amidation of peptides is required for normal developmental transitions and for biosynthesis of secretory peptides throughout the life.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2
- Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 1
- Protein dimmed
Sequence:
MPRISEIAASVGLLLLIGVISVDGLVKEGDYQNSLYQQNLESNSATGATASFPFLMPNVSPQTPDLYLCTPIKVDPTTTYYIVGFNPNATMNTAHHMLLYGCGEPGTSKTTWNCGEMNRASQEESASPCGPHSNSQIVYAWARDAQKLNLPEGVGFKVGKNSPIKYLVLQVHYAHIDKFKDGSTDDSGVFLDYTEEPRKKLAGTLLLGTDGQIPAMKTEHLETACEVNEQKVLHPFAYRVHTHGLGKVVSGYRVRTNSDGEQEWLQLGKRDPLTPQMFYNTSNTDPIIEGDKIAVRCTMQSTRHRTTKIGPTNEDEMCNFYLMYYVDHGETLNMKFCFSQGAPYYFWSNPDSGLHNIPHIEASTL
Protein: Lipase member I (LIPI) (EC 3.1.1.-) (Cancer/testis antigen 17) (CT17) (LPD lipase) (Membrane-associated phosphatidic acid-selective phospholipase A1-beta) (mPA-PLA1 beta) (Q6XZB0)
Organism: Homo sapiens (Human)
Function: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:12963729}. Secreted {ECO:0000269|PubMed:12963729}. Note=May associate with lipid draft. {ECO:0000269|PubMed:12963729}.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane {ECO:0000269|PubMed:12963729}. Secreted {ECO:0000269|PubMed:12963729}. Note=May associate with lipid draft. {ECO:0000269|PubMed:12963729}.
Interaction partners:
- GAS2-like protein 2
- Apolipoprotein A-V
- Growth arrest-specific protein 2
- GAS2-like protein 1
- Heat shock 70 kDa protein 13
Sequence:
MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT
Protein: Toll-like receptor 3 (Q32PW5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MDLMKLILLPLFYACFSAHCAGTTNARKSACMIKNAKADCSHMNLDAIPTDLPTNITTLDVSHNRLKTLSSLHMYTNLVNIDASYNSLAGIEKDLCLSLPHLQFLNVQHNQVYLISEKNLKNCFHLTQLDLSDNKLKLQGEPFSLLKNLTWLDVSRNKLTSAKLGTEPQLPNLVTLVLSGNNINILQENDFSFLSNSSSFRVLILSSLILKKVENGCFKAIDTLSDLVLDSSKLTSQFTTSLFEELADTALRNLSLKSTEQVTLSNTTFQGLEKTKITVLDLSENRISKIVDGAFQWLPQLEFLSLEHNTIRHLTNDSFSGLGNLRQLNLRKALIKSHASLPVIDDFSFQHLVQLEYLCMANTAFRELTEQIFSGLRNLKTLDLSWSITGIKTVTNKTFAGLQESPLLQTLNLTGMGINKLEPGAFSSLGNLSNLLMSRNFINQQLQGNEFKGLSNIKEIDMSINQQSISLTNASFVHVSTLRTLKLGRALKGTLDMEPSPFRPLVNLTILDLSNNNIANINADLLEGLYNLKVVKMQHNNLARLWKMANPGGPVLFLKDATNLSYLNLDYNGIDEIPPNAFRGFSELHELSLRGNLLDQLHASVFDDLNSLKYLHLQKNLITSVQRATFGVPLSKLKELNMDHNPFDCTCESILWFSEWLNSTNTSVPGFPQSYICNTPNAYFNHSVMNFDPLSCKDMTPFKALYILSSTAVLMLLFISFLVHFQGWRIQFYWNIMVNRMLGSLKDAKVTEGRFQFDAYIIHAGEDKSWVERSLLSLEDKDLNFFYEQRDSTPGHSRLETIVDNMVYSRKIIFVITEMLLKDPWCRQFKAHHALHHVMEDNRDSLILIFLEDVTDYNLNRSLHLRRGMLKPKCVLYWPLHKERIPAFHQKLRSALASTNKVN
Protein: Importin N-terminal domain-containing protein (Q385Z4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- RNasePH-like protein exosome-associated protein 1 Rrp42 homologue
- Ribosomal RNA processing protein 45
- Exosome component CSL4
- Ribosomal RNA processing protein 4
- Ribosomal RNA-processing protein 43
- Exosome complex exonuclease RRP40
- Telomerase-associated protein, putative
- Small ribosomal subunit protein uS5
- GTP-binding nuclear protein
- 40S ribosomal protein S14
Sequence:
MVDEETLVQIFTATLSADKATRKEAETALANLSNDPNIIPQLIRFACNDLRQAGAAAQVAQHAASIRVRNVVGRSDWNRQSYFTENVKANVRDCIVPLQCSSHVPPAVRRQLLDTTQELITYDYPASWPTLMPQLTSILDECVNVLNSDVGAVATPPYETAAARLRAALGVLLACCRYYNNPINVDAEAVDDFVDRIGPSLVSLAELLGSAWGQELLQHSHAVCQTGVPLTFEISPLHTVLTDCLRIVLKCFHELTASRWPRFLCERPEMEHFCRVCVVQLSEAAYSTLLPLYRHRISSCEDDENGEVDLATTDESAVWKLLKWVTRLSYQLVQELMFPKKCESRARGSAKYFCENILLPLVQQALEFIRWHASPRIVTSKAYILALEIITLAVEHSAVYRQILFPNAGELLTQLLFPRLAFSSVDAELWSTNPVEYVRRQTDPQEDMYSARVVSGSLILALTTPSRPFHDALALTNFMHFVLEKLSTHSAAAACGAVEESRVVDACFFAVYQFGGMLDVAGFPNERVEWLITEYIIPAAAYPAGILRARCALVLSVLAPKIKWSSSQAYQRVVHVVLRLLQDAEPPVRIQACSSFAPLICHPFAHEVITPVIGEVIQNYFSAMRMMDNEGVVRTLRKTIRHYRRTLSQWALQLTDVLAQHFEQMLGRALSEGHTDSVLESLDACNSEKSSKTLGGAGESTVSDSIMAADEVLDTLVTLVRSLPQPNVSTPGSQPVDDLLLQIQERTAPMLFAVLAQEGGSCFGFMDATLMLLTTVLSKSTAVSTGTWKLLLCLYQLVSQGSVDYFSQMLPPLDNFVCVAPREFLCFPMKELCEVPTFAAGVADSTPAQLVSIMCDTVLNNESDLRLSELAAVPKMYDSMLQNLWSLKQKNPEEGESRVAAARGLVEYVIQTALRVLNDPQCRQMHRRTFTILFVNSVFSAILADPDLAIRSLSSAGALVPLFANYIELVQGKELQAMLRSYDRRLFIMTVASVTQIMCAKDQQMSDCVAEVLCGVLQSSVLTDFSHAELVMAEEEAKKPELGDDGEDEWSNDGLDDDLVDNAEDEDEDDDDEWDDDGEDSDDDLDANGMADEGHLQALLMEAAAARKDGKGGAGCDEEEENLLDEADFVSPIDSCNAWSLLLSAVNLCSLSAASAPPAQFIQVAKGAAAQQQLSAVQQVSDMMGQLMVLREQRKGAARSS
Protein: Nucleosome assembly protein 1-like 1 (B9EPV8)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MADMDNKDQAELDPADLEDVEDVEEEETGEDVNSKARQLTVQMMQNPQILAALQERLDGLVGSPSGYMESLPKVVKRRVNALKNLQVKCAHIEAKFYEEVHELERKYAALYQPLFDKRSDIVKAAYEPTEEECEWKADEEEELTEEMKEKAKVEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMLQEHDEPILKHLQDIKVKFSDPGQPMSFSLEFYFEPNEFFTNTLLTKTYKMRSEPDENDPFSFDGPEIMGCTGCTIDWTKGKNITLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFTPPDVPESGDLDEDSEAVLAADFEIGHFIRERIVLRAVLYFTGEAIEDDDDDYDEEGEEADDEEGEEEGEEENDPDYDPKKDANPPAECKQQ
Protein: Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (P61979)
Organism: Mus musculus (Mouse)
Function: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P61978}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:P61978}. Cell projection, podosome {ECO:0000250|UniProtKB:P61978}.
Interaction partners:
- Poly
- Heterogeneous nuclear ribonucleoprotein U
- Polypyrimidine tract-binding protein 1
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoproteins C1/C2
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Heterogeneous nuclear ribonucleoprotein A3
- Nucleolin
- RNA binding motif protein, X-linked-like-1
Sequence:
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF
Protein: Intraflagellar transport protein 56 (Tetratricopeptide repeat protein 26) (TPR repeat protein 26) (A0AVF1)
Organism: Homo sapiens (Human)
Function: Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme.
Subcellular location: Cell projection, cilium {ECO:0000250|UniProtKB:Q8BS45}. Note=Localizes at the base to the ciliary transition zone. {ECO:0000250|UniProtKB:Q8BS45}.
Interaction partners:
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 52 homolog
- Intraflagellar transport protein 70B
- Intraflagellar transport protein 88 homolog
- Transitional endoplasmic reticulum ATPase
- Intraflagellar transport protein 57 homolog
- UBX domain-containing protein 10
- Intraflagellar transport protein 27 homolog
- Ubiquitin recognition factor in ER-associated degradation protein 1
- Nuclear protein localization protein 4 homolog
Sequence:
MMLSRAKPAVGRGVQHTDKRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTNLWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEAELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQSEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMIIAGREPKETLREVLHLLRSTGNTQVEYMIRIMKKWAKENRVSI
Protein: Integrin subunit alpha E (A0A8I5Y1Q1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Interaction partners:
Sequence:
MKWFFHALLCVASLKPLGAFNVDVDWSWVTALQPGAPSVLNSLLHQDPSNNQTCLLVARRSSNRNSAVLYRCATSIIPDEIGCQPVEHILMPKGRYQGVTLVRNHNGVLVCIQVQSRKPRSLNSELTGACSLLTPNLDLQAQAYFSDLEGVLDLGASVNSGDYYGSKGGSTGEETKSARRLRRQAVEEEDEEEAGTEIAIVLDGSGSIEPSDFQKAKDFISTMMRNFYEKCFECNFALVQYGGVIQTEFDLLDSRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFRDPLNLTTVISSSKMQGVVRFAIGVGNAFENNNTYRELKLIASDPKAAHTFKVTNYSALDGLLSKLQQRIIHMEGTVGDTLQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALLYNTQNGRGRFLNQTAKEDFRAAQYSYLGYSVAALHKAHGVSYVAGAPRHKLRGAVFELQKEDGEETFMRRIEGEQMGSYFGSVLCPVDINMDGITDFLLVAAPFYHIRGEEGRVYVYRVHEQDAPFSLVYTLSGYPGLTSSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLHASPSQQIRASSVALGLYYFGMSVSGGLDFSGDDLADITVGSQDVAVVLRSRPVVDLTVSMTFTPDALPMAFKDKMDVELCFKVDSSAVPSEPGLRGMSLNFTVDVDVTKQKQRLQCADRSCCQSCLMKWSGGSSLCEHFGLISTEEELCEDDCFSNITIKVSYEFQTSEERRNHPNPILDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTAISQQDLVVGITKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPLSPDIQCDDPKPVASVLVMNCKIGHPILKRSSVNVSVTWQLEESIFPNRTADITVTISNSNEKSLARETHSLQFRHAFIAVLSRPSVMYMNTSQSSSDHKEFFFNVHGENHFGAVFQLQICVPITLRDLQIIRVKHLTKTQVFKWDSLL
Protein: Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) (Q9I730)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable sulfate transporter
- Cyanate hydratase
- Carbonic anhydrase
- Carbonic anhydrase
- DUF485 domain-containing protein
- Serine/threonine transporter SstT
- Amino acid ABC transporter membrane protein
- Transcriptional regulator CynR
- Glutamate/aspartate import permease protein GltK
- GTPase Era
Sequence:
MPDRMRGVKSDSPEQESADDALKRIVDGFQHFRREVFPEQQALFKKLANSQRPRAMFITCADSRIVPELITQSSPGDLFVTRNVGNVVPPYGQMNGGVSTAIEYAVLALGVHHIIVCGHSDCGAMRAVLDPQTLERMPTVKAWLRHAEVARTVVADNCDCGASHDTLGVLTEENVVAQLDHLRTHPSVASRLASGQLFIHGWVYDIESAQIRAYDAKQGRFLPLDGEHPVPMATPAPRYLSS
Protein: 26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Proteasome subunit p39B) (Proteasome subunit p40) (Protein Mov34) (P26270)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome non-ATPase regulatory subunit 4
- 26S proteasome regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 1
- Probable 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome regulatory complex subunit p50
- Regulatory particle triple-A ATPase 4
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 14
Sequence:
MPSQEVSVNKVIVHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPNSVLVIIDAKPKDLGLPTEAYISVEEVHDDGSPTSKTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQKITNQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDITNDQFTGTMYVKTNDQMLVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSKEAKEKNKDSKDKDNKETKDKDGKKAEEKADKGKDEGGKGSRK
Protein: Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A) (Q86SG5)
Organism: Homo sapiens (Human)
Function: May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Protein S100-A7
Sequence:
MSNTQAERSIIGMIDMFHKYTGRDGKIEKPSLLTMMKENFPNFLSACDKKGIHYLATVFEKKDKNEDKKIDFSEFLSLLGDIAADYHKQSHGAAPCSGGSQ
Protein: Histone deacetylase (EC 3.5.1.98) (Q9VNC2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR037913}.
Interaction partners:
Sequence:
MTDRRVSYFYNADVGNFHYGAGHPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYIAYLQQVTPQNIQCNSVAYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICINWSGGLHHAKKFEASGFCYVDDIVIGILELLKYHPRVLYIDIDVHHGDGVQEAFYLTDRVMTASFHKYGNYFFPGTGDMYEIGAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAGDRLGCFSLSTKGHGECVKFVKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIENDLPATEYYDFFAPDFTLHPEINSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPDVDLEELRSNREEASDPDVRISVADEDKLVDAKNEFYDGDQDQDKPDSAES
Protein: Putative metal tolerance protein C3 (AtMTPc3) (AtMTP8) (Q9M2P2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Tonoplast.
Interaction partners:
- Metal tolerance protein A2
- Metal tolerance protein 12
- Metal tolerance protein C2
- Metal tolerance protein B
- Metal tolerance protein 1
- Metal tolerance protein C4
- Metal tolerance protein A1
- Metal transporter Nramp4
- Solute carrier family 40 member 2
- Vacuolar iron transporter 1
Sequence:
MEVNYCPETPLLSSNDHEAIDHKPKLTGMVSSMKSNFFADLPQKLRSKIDPENPLHLDVSKAAGLKEDEKEYYERQLATLKSFEEVESFLARSDEYTIDEKEEEEDRAERAAQELAMQISNWANIFLLALKIYATVKSGSIAIAASTLDSLLDLMAGGILWFTHLSMKNVNIYKYPIGKLRVQPVGIIIFAAVMATLGFQVLLVAAEQLISNEPSEKMNHVQLIWLYSIMLSATAIKLVLWIYCKSSRNHIVRAYAKDHHFDVVTNVLGLVAAVLANAFYWWLDPTGAILLAIYTIVNWSGTVMENAVSLIGQSAPPEVLQKLTYLVMRQGGDNIKHVDTVRAYTFGVLYFVEVDIELPEDLPLKEAHAIGESLQIKLEELPEVERAFVHLDFECHHKPEHSVLSTIPNDL
Protein: LD15632p (Q95RR0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPLPAVVSFPKPPKAPDGSLVYDRVPNKSPDVVAVPADKELTIIPTQATSTIRKRAHEDQQLNGTEVTIVPSGPPAKRPNKDPMPSHCPSPEQFAAMMAASGQPLSRHHLNGKQKIAQMARGGNGRKQVISWMDAPDDVYFRANDTHKKTRKILSAVDLRRAARKPWRTLPIKPAAPEPSSRPIESQIVILD
Protein: Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50) (Q9UBX5)
Organism: Homo sapiens (Human)
Function: Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN.
Subcellular location: Secreted {ECO:0000269|PubMed:16652333, ECO:0000269|PubMed:17035250, ECO:0000269|PubMed:20599547}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17035250}. Note=co-localizes with ELN in elastic fibers. {ECO:0000269|PubMed:17035250}.
Interaction partners:
- Elastin
- Lysyl oxidase homolog 1
- Protein-lysine 6-oxidase
- Fibrillin-1
- Latent-transforming growth factor beta-binding protein 2
- Fibronectin
- V-type proton ATPase 116 kDa subunit a 2
- Lysyl oxidase homolog 2
- Microfibrillar-associated protein 2
- Microfibril-associated glycoprotein 4
Sequence:
MPGIKRILTVTILALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF
Protein: Transcription factor Spi-B (O35906)
Organism: Mus musculus (Mouse)
Function: Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. Required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q01892}.
Interaction partners:
- Interferon regulatory factor 8
- Interferon regulatory factor 4
- POU domain class 2-associating factor 1
- B-lymphocyte antigen CD19
- B-cell antigen receptor complex-associated protein beta chain
- B-lymphocyte antigen CD20
Sequence:
MLALEAAQLDGPHLSCLYPEGVFYDLDSCKPFSYPDSDGGLDSTWGWTEAPPAPAIAPYEAFDPATAAFSHSQTVQLCYSHGPNPSTYSPMGTLDPAPSLEAPGPGLQVYPPEDFTSQTLGSLAYAPYPSPVLSEEEDIMLDSPALEVSDSESDEALLAGSEGRGSEAGARKKLRLYQFLLGLLLRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALLPASRHV