wanglab/gogpt-training-data huggingface dataset:
Protein: Probable G-protein coupled receptor 34 (B0S6P9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MNNYSQNYHNESLTRRQEPQNCYMDNTSLRIPLAVFYTLFFLFGFAGNLLALWVFLRLHPKKNSVRIFLINLALADILLVICLPFRVAYHFNNNQWVLPSLLCRIVGNVFYMNMYISIALLGFISVDRYLKFHRASSRRWFLQSHWSAIVCGVLWAVSIAGVSPFIVKTENNNETHQCFQYKKLCDSKWKAYFNFVIVAIFWVVYGALVMSYGRIGMKLITASRDKPDFPNAAKYNKTAWKSFFVLFTFTVCYAPYHFVRIFYIMSQMAPNVSCNKMNVLDKTNEVVLLLSALNSCLDPVMYFLLCSSIRKVTLKFICNCFCQQTNNALNSSSDEQPKIMTVVPKTICQDIKKATIIIK
Protein: Membrane-associated protein VP24 (Ebola VP24) (eVP24) (Q05322)
Organism: Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus)
Function: Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways. Blocks the IFN-induced nuclear accumulation of host phosphorylated STAT1 by interacting with the STAT1-binding region of host importins. Alternatively interacts also directly with host STAT1 and may additionally inhibit its non-phosphorylated form. Plays a role in assembly of viral nucleocapsid and virion budding. May act as a minor matrix protein that plays a role in assembly of viral nucleocapsid and virion budding.
Subcellular location: Virion membrane {ECO:0000269|PubMed:12525613}; Peripheral membrane protein {ECO:0000269|PubMed:12525613}. Host cell membrane {ECO:0000269|PubMed:12525613}; Peripheral membrane protein {ECO:0000269|PubMed:12525613}; Cytoplasmic side {ECO:0000269|PubMed:12525613}. Host endomembrane system {ECO:0000269|PubMed:12525613}; Peripheral membrane protein {ECO:0000269|PubMed:12525613}. Note=In virion, localizes on the intravirional side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and to the plasma membrane where budding takes place (By similarity). {ECO:0000250}.
Interaction partners:
Sequence:
MAKATGRYNLISPKKDLEKGVVLSDLCNFLVSQTIQGWKVYWAGIEFDVTHKGMALLHRLKTNDFAPAWSMTRNLFPHLFQNPNSTIESPLWALRVILAAGIQDQLIDQSLIEPLAGALGLISDWLLTTNTNHFNMRTQRVKEQLSLKMLSLIRSNILKFINKLDALHVVNYNGLLSSIEIGTQNHTIIITRTNMGFLVELQEPDKSAMNRMKPGPAKFSLLHESTLKAFTQGSSTRMQSLILEFNSSLAI
Protein: GRB2-related adaptor protein 2 (Adapter protein GRID) (GADS protein) (GRB-2-like protein) (GRB2L) (GRB-2-related monocytic adapter protein) (MONA) (Monocytic adapter) (GRBLG) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adaptor protein GrpL) (O89100)
Organism: Mus musculus (Mouse)
Function: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}.
Interaction partners:
- Lymphocyte cytosolic protein 2
- Linker for activation of T-cells family member 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Growth factor receptor-bound protein 2
- Proto-oncogene vav
- SHC-transforming protein 1
- Mitogen-activated protein kinase kinase kinase kinase 1
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase ZAP-70
- Tyrosine-protein phosphatase non-receptor type 23
Sequence:
MEATAKFDFMASGEDELSFRTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQVFLRDGTQDQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGPQQFHPHQQPSPQFTPGPQPPQQQRYLQHFHQDRRGGSLDINDGHCGLGSEVNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR
Protein: NADPH-dependent FMN reductase Lot6, putative (AFU_orthologue AFUA_7G06600) (C8VD04)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MRLGALLSVTLLSTAATAAFNAQDTIDRDVVILGGGATGTFAAVQLREQGYTVALVEQKSKLGGHAETLYLPSGDYVNYGVEGYFNNKITKDFFAQLDVDYEPLLPGAILTQHVNFRTGERVLPGNELLTTTAAALLYRGAIEQFNYLAQGLYDLPEEVPEILLRPFREFVDKYALWGAVDLIFTFAENVGNMLDRPTLYVIQYFGIPHIDALLNGGYIRPKNGTDVLFNKAANYIDEVNNIFYDSMAVRTTRDETGVEVVIQNARTGAQKLIRAKKLLIAFPPVLEKLAGFDLTEQESALFSKWTYVNYYAAVLTNTAVPNDFNILNTDPTNQPGSLPTTPFNWALEYSGVPGYFMNKIIGDANLTEAEARALIIDDLKRMSSAGTFGIKDGQEPEIAAFASHSPETLMVSVEDVKGGFYKKLYGLQGQASTFYTGYTFCTDYSTMLWNYTNTIVDRIVQEL
Protein: Tyrosyl-DNA phosphodiesterase 1 (Q4Q3N1)
Organism: Leishmania major
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- DNA-
- DNA topoisomerase I
- DNA topoisomerase type IB small subunit
- Putative KU70 protein
- Uncharacterized protein
- Flap endonuclease 1
- Putative KU80 protein
- Putative DNA repair protein
Sequence:
MIELMVCPLTVLCAWLFHAALSGREGSQTQPVFLHCCHCPFFYLVAAATVRAASVDAHPAAPPSLCGYPFVCRATLSSLSFPSVYTRRATTQTSHLCVSAWICLPTRSCSRSSPFPRCRGRRLRCAHPNCVADPSLPPHHIPRRALMNGGGAARHAEAGFPFWVNDIDSFPSALQRHAPLSRSLLRLRDLFRCDVADPGECWQHILLSSYVTDLRWLLATVPELSAVTGKLVVLSGEKGTATLRRTTGDPSSPYTAVPPLMDRVNPFMTALREQASGTSPLHTALSRERLAVLEPPLPVAFGTYHTKMALCINGKGLRVSIFTANLVEQDWCWKSQGIYVQDFPWKPVTERSNDDSAGTIMVETAARSTSNSNNGSNTFTKGAEFVAHLRHYLMRCGVSLASACASPADAASAAGPLGIFETDFLSHIDFTAAAVWLVSSVPGTYAHGEVCPVYRVGLCRLGEVLRRSALTTATAPASVDLSWQYSSQGSLNPAFLNSLQAAMCGESVAVIESGDAPRGVRDVQVVYPTEEEVRNSWEGWRGGGSLPLCVQCCHEFVNARLHCWGSSEAGHMAKRAFPRPAKVAAVHASREDAVDVDGVDSDGGEGTPVSLAGSCAAYRRFALPHIKSYAAVAPDRSCVRWFLLTSANLSQAAWGSLSRKVNQHGSRQQLVRSYELGVLYDSHSAIYQSASSWFSVVAKSKIELPNACNSRAMLYETPLGIGTQDVCLYTPYNLLCPTPYASTAALRAHRDAPDKGEQAVAGAALDCSDVPWVLDMPHRGRDAYGLEVEEAFESIVSPNLSKWQPRTRAMETAPLRNIGAPRKRTREA
Protein: Protein AGENET DOMAIN (AGD)-CONTAINING P1 (Protein ONE AGENET DOMAIN-CONTAINING PROTEIN) (Q500V5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Heterochromatin-binding protein that preferentially occupies long transposons and specifically recognizes the histone H3 'Lys-9' methylation (H3K9me) marks, with a stronger affinity for dimethylated H3K9 (H3K9me2). Required for transcriptional silencing, non-CG DNA methylation (e.g. CHG and CHH regions), and H3K9 dimethylation (H3K9me2) at some loci. Mediates heterochromatin phase separation and chromocenter formation.
Subcellular location: Nucleus {ECO:0000269|PubMed:30382101, ECO:0000269|PubMed:30425322}. Note=Enriched in heterochromatin, concentrated in centromeric and pericentromeric regions. {ECO:0000269|PubMed:30382101, ECO:0000269|PubMed:30425322}.
Interaction partners:
- UPF0235 protein At5g63440
- VAMP-like protein YKT61
- Probable cysteine protease RD21C
- At1g09850
- Cysteine proteinase RD21A
- Probable cysteine protease RD21B
- ADP-ribosylation factor GTPase-activating protein AGD12
- Vesicle-fusing ATPase
- Alpha-soluble NSF attachment protein 2
- Alpha-soluble NSF attachment protein 1
Sequence:
MLRPRRSLGVSSPAKQRKKAAPKNSMATRANRKRLPSYLKPGSAVEISSDEIGFRGSWYMGKVITIPSSSDKDSVKCQVEYTTLFFDKEGTKPLKEVVDMSQLRPPAPPMSEIEKKKKIVVGEEVDAFYNDGWWEGDVTEVLDDGKFSVFFRSSKEQIRFRKDELRFHREWVDGAWKPPLEETEEEEDESEEDKLDDSEDEEDILARVDLETTRAIAKQMFSSGTVVEVSSDEEGFQGCWFAAKVVEPVGEDKFLVEYRDLREKDGIEPLKEETDFLHIRPPPPRDEDIDFAVGDKINAFYNDGWWVGVVIDGMKHGTVGIYFRQSQEKMRFGRQGLRLHKDWVDGTWQLPLKGGKIKREKTVSCNRNVRPKKATEKQAFSIGTPIEVSPEEEGFEDSWFLAKLIEYRGKDKCLVEYDNLKAEDGKEPLREEVNVSRIRPLPLESVMVSPFERHDKVNALYNDGWWVGVIRKVLAKSSYLVLFKNTQELLKFHHSQLRLHQEWIDGKWITSFKSQKV
Protein: PDEase domain-containing protein (Q3TMR0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
QICGPLFLQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLEETDIDIATEDKSPIDT
Protein: Uncharacterized protein (Q38BW5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Manganese/iron superoxide dismutase C-terminal domain-containing protein
- Ubiquitin-like domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MVFYSFVLVMKPRQRRFTSQALREIGVAVYSNGGLIRSITNEGIMRPYSRFRDADNTPLTYARYIILQLDMGEEEMGKVDKIIREHQDVLMALKLNNLERPVGIRSGNKELQAAYFPLDTFTRLEEEINWSPQTSADIYTQLEMNWKEFSRTRWSSFLRN
Protein: IS1540, transposase (O06247)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MIDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVTDPSGPRESAQPRALSAAEREHVLAVLNSQRFADMAPAVVYATLLDEGIYLCSESTMYRLLRERGQTGDRRRQATHPAAVKPELVAHQPNSVWSWDITKLRGPAKWSYYYLYVILDIFSRYVVGWMVASRESKVLAERLIAQTLAAQHISADQLTLHADRGSSMSSKPVALLLADLGVTKSHSRPHTSNDNPLSEAQFKTLKYRPDFPKRFESIEAARVHCDRFFGWYNHEHKHSGIGLHTPADVHYGRADQIRRHRATVLDTAYRDHLERIRSQTTRATRATGLQRDQPTTEGGPADSINPRKSCLRNVDRFRPGLLDLPAPAPVDLRRLLPSGQIR
Protein: Actin-related protein 2 (A0A1D8PTX1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Actin-related protein 3
- Arp2/3 complex 34 kDa subunit
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 5
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2/3 complex subunit
- Actin-binding protein
- Actin
- SPIN90/Ldb17 leucine-rich domain-containing protein
- Centractin
Sequence:
MSTPIVLDQGTGFVKIGRAGTNFPDHTFPSMVGRPILRAEERNILVPSDVEIKDIMCGSEASQVRSLLQINYPMENGIIKNWEDMEHLWDYAFYERMKINPQGQKILLTEPPMNPLKNREMMCQVMFEKYGFDGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLNHLTKRLDVAGRDVTRHLINLLFRRGYAFNRTADFETVRQIKEKLCYVSYDLGFDAKLARETTTLVESYELPDGRVIKVGSERFEAPECLFQPHLVDVEQPGVGETLFNTIQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWLTRVLQGDASRLDKFKVRIEDPPRRKHMVFIGGAVLANIMADKDHMWISKQEWEEQGPRVLEKLGPR
Protein: Triplex capsid protein 2 (P10202)
Organism: Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Function: Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04019}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04019}.
Interaction partners:
Sequence:
MLADGFETDIAIPSGISRPDAAALQRCEGRVVFLPTIRRQLTLADVAHESFVSGGVSPDTLGLLLAYRRRFPAVITRVLPTRIVACPLDVGLTHAGTVNLRNTSPVDLCNGDPISLVPPVFEGQATDVRLDSLDLTLRFPVPLPSPLAREIVARLVARGIRDLNPSPRNPGGLPDLNVLYYNGSRLSLLADVQQLGPVNAELRSLVLNMVYSITEGTTIILTLIPRLFALSAQDGYVNALLQMQSVTREAAQLIHPEAPALMQDGERRLPLYEALVAWLTHAGQLGDTLALAPVVRVCTFDGAAVVRSGDMAPVIRYP
Protein: TBC1 domain family member 1 (Q86TI0)
Organism: Homo sapiens (Human)
Function: May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Ras-related protein Rab-10
- Ras-related protein Rab-8A
- 5'-AMP-activated protein kinase subunit beta-1
- 5'-AMP-activated protein kinase subunit gamma-3
- 5'-AMP-activated protein kinase subunit beta-2
- Ras-related protein Rab-14
- 5'-AMP-activated protein kinase subunit gamma-1
- 5'-AMP-activated protein kinase subunit gamma-2
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- Ras-related protein Rab-2A
Sequence:
MEPITFTARKHLLSNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSRQSTRKEPVTKQVRLCVSPSGLRCEPEPGRSQQWDPLIYSSIFECKPQRVHKLIHNSHDPSYFACLIKEDAVHRQSICYVFKADDQTKVPEIISSIRQAGKIARQEELHCPSEFDDTFSKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSGSRGSESPRPNPPHAAPTGSQEPVRRPMRKSFSQPGLRSLAFRKELQDGGLRSSGFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQSLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHIHIGEMKQTSQMAAENIGSELPPSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSISVDLDSSLSSTLSNTSKEPSVCEKEALPISESSFKLLGSSEDLSSDSESHLPEEPAPLSPQQAFRRRANTLSHFPIECQEPPQPARGSPGVSQRKLMRYHSVSTETPHERKDFESKANHLGDSGGTPVKTRRHSWRQQIFLRVATPQKACDSSSRYEDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDIAKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQAMLTLELERSALLQTVEELRRRSAEPSDREPECTQPEPTGD
Protein: KASH domain-containing protein (G8JYF1)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MDGRVTVDSCTSSSEDQMVEQSTNKKWESVLQDVGYSSGENSIHEALNTCADHLVPETSDMRRKRIECSPVKAFYRTVQLEDMSDLEVTKAINHDVEEEPNLSDSMYVNHDSTFLATQNLPEYDEVMALMDDDDLPMDMSMTESFNTKWREIHGQKKPLRRASRPSREQMNLIAKSSCDASSEDSSEGENQTNLEDDPEMMSVSFNSAQFDTSSPLKRQRSARGLKNASFLYDSLEMDGSFCSTRSEMLPPCKTRSLARRKLRVRRMPRSMSDGEQLGVVSSKPEGMMTPMIRVSPPSTPVRRLLRKLDEQIRNRDSDTAPEHSDAAQAYEWDEYNPPQKDDSISDRHIQTMTDISDQLMNIDDDFAEHFGTSSAIRLIEESKSHLRVVLKALEESDSNIPQLSNFELIARSNLRQVDEALKIQSGNQPSFLETSTLQDLRSEWANLYESIRSPFARIMHQVKKFAATLQEVSSMASLGDVDIRSKEDVAKTLDAVTAIERRLSSERQELRDLLASSSFRDVAKDLSCEFESVSEGYDDAVDKIGKMAHSLSQVKGEWDAWNSRQNDIRNAMVRIESHLKEGQMDNKMIADEMELCQERMNSLETMCNYLTASLGSIQNESNSKNLPDFKAELSIYSNALARLKDRFNDMIRVPTPPTVQFHPPEPLPSLARSMTTQTAEMESETENEPLTIAEAISSSRLIKFTFALSLLAALAAIFYYHVFGKPFGPHVTYVNGPPPV
Protein: Sucrose synthase 2 (OsSUS2) (EC 2.4.1.13) (Sucrose synthase 1) (RSs1) (Sucrose-UDP glucosyltransferase 2) (P30298)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways (By similarity). Functions in developing seeds by supplying substrates for the biosynthesis of storage products.
Interaction partners:
- Probable sucrose-phosphatase 3
- Probable sucrose-phosphatase 1
- Sucrose-phosphatase 2
- Starch synthase, chloroplastic/amyloplastic
- Granule-bound starch synthase 1, chloroplastic/amyloplastic
- UTP--glucose-1-phosphate uridylyltransferase
- UTP--glucose-1-phosphate uridylyltransferase
- Glucose-1-phosphate adenylyltransferase small subunit 2, chloroplastic/amyloplastic/cytosolic
- Os01g0196600 protein.
- Glucose-1-phosphate adenylyltransferase large subunit 4, chloroplastic/amyloplastic
Sequence:
MAAKLARLHSLRERLGATFSSHPNELIALFSRYVNQGKGMLQRHQLLAEFDALIEADKEKYAPFEDILRAAQEAIVLPPWVALAIRPRPGVWDYIRVNVSELAVEELSVSEYLAFKEQLVDGHTNSNFVLELDFEPFNASFPRPSMSKSIGNGVQFLNRHLSSKLFQDKESLYPLLNFLKAHNHKGTTMMLNDRIQSLRGLQSSLRKAEEYLMGIPQDTPYSEFNHRFQELGLEKGWGDCAKRVLDTIHLLLDLLEAPDPANLEKFLGTIPMMFNVVILSPHGYFAQSNVLGYPDTGGQVVYILDQVRALENEMLLRIKQQGLDITPKILIVTRLLPDAVGTTCGQRVEKVIGTEHTDILRVPFRSENGILRKWISRFDVWPFLETYTEDVANEIMREMQAKPDLIIGNYSDGNLVATLLAHKLGVTQCTIAHALEKTKYPNSDIYLDKFDSQYHFSCQFTADLIAMNHTDFIITSTFQEIAGSKDTVGQYESHIAFTLPGLYRVVHGIDVFDPKFNIVSPGADMSVYFPYTEADKRLTAFHPEIEELLYSEVENDEHKFVLKDKNKPIIFSMARLDRVKNMTGLVEMYGKNAHLRDLANLVIVCGDHGNQSKDREEQAEFKKMYGLIDQYKLKGHIRWISAQMNRVRNGELYRYICDTKGVFVQPAFYEAFGLTVIEAMTCGLPTIATCHGGPAEIIVDGVSGLHIDPYHSDKAADILVNFFEKCKQDSTYWDNISQGGLQRIYEKYTWKLYSERLMTLTGVYGFWKYVSNLERRETRRYIEMFYALKYRSLASAVPLAVDGESTSK
Protein: G2/mitotic-specific cyclin-B2 (O95067)
Organism: Homo sapiens (Human)
Function: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Interaction partners:
- Cyclin-dependent kinase 2
- Cyclin-dependent kinase 1
- Cell division cycle protein 20 homolog
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- G2/mitotic-specific cyclin-B1
- Serine/threonine-protein kinase PLK1
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- M-phase inducer phosphatase 3
- Baculoviral IAP repeat-containing protein 5
- Aurora kinase B
Sequence:
MALLRRPTVSSDLENIDTGVNSKVKSHVTIRRTVLEEIGNRVTTRAAQVAKKAQNTKVPVQPTKTTNVNKQLKPTASVKPVQMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS
Protein: Polyamine transporter PUT1 (Polyamine uptake transporter 1) (OsPUT1) (Q6Z8D0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Cell membrane polyamine/proton symporter involved in the polyamine uptake in cells. Possesses high affinity for spermidine and lower affinity for spermine and putrescine. Transports paraquat, a polyamine analog, and thus confers sensitivity to this chemical which is used as a herbicide.
Subcellular location: Cell membrane {ECO:0000305|PubMed:21796369}; Multi-pass membrane protein {ECO:0000305|PubMed:21796369}. Note=Plasma membrane.
Interaction partners:
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Os12g0534000 protein
- Os01g0375200 protein.
- 3-dehydroquinate synthase, chloroplastic
- Os01g0375500 protein
- Os01g0375350 protein
- Alpha-amylase isozyme 3E
- Alpha-amylase isozyme 3A
- Os08g0391501 protein
- Expressed protein
Sequence:
MADTGGRPEVSLATVRSPGHPAASTTAAAAADLGHADTGQEKPTVESAQPANGAAPMGECGTEYRGLPDGDAGGPMPSSARTVSMIPLIFLIFYEVSGGPFGIEDSVGAAGPLLAIIGFLVLPVIWSIPEALITAELGAMFPENGGYVVWVASALGPYWGFQQGWMKWLSGVIDNALYPVLFLDYLKSGVPALGGGAPRAFAVVGLTAVLTLLNYRGLTVVGWVAICLGVFSLLPFFVMGLIALPKLRPARWLVIDLHNVDWNLYLNTLFWNLNYWDSISTLAGEVKNPGKTLPKALFYAVIFVVVAYLYPLLAGTGAVPLDRGQWTDGYFADIAKLLGGAWLMWWVQSAAALSNMGMFVAEMSSDSYQLLGMAERGMLPSFFAARSRYGTPLAGILFSASGVLLLSMMSFQEIVAAENFLYCFGMLLEFVAFILHRVRRPDAARPYRVPLGTAGCVAMLVPPTALIAVVLALSTLKVAVVSLGAVAMGLVLQPALRFVEKKRWLRFSVNPDLPEIGVIRPPAAPDEPLVP
Protein: Ras association domain-containing protein 4 (Q9H2L5)
Organism: Homo sapiens (Human)
Function: Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Interaction partners:
- Serine/threonine-protein kinase 3
- Ras association domain-containing protein 2
- Serine/threonine-protein kinase 4
Sequence:
MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK
Protein: Adenylate kinase, putative (EC 2.7.4.3) (Q586D5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Adenylosuccinate lyase
- Adenosine kinase
- Adenosine kinase
- adenine phosphoribosyltransferase
- adenine phosphoribosyltransferase
- Pyruvate kinase
- Phosphodiesterase
Sequence:
MAVLSEDVLLYLKEKNIPMLFEQIVQNIISDAPERPMSYIGDLMRRGIPLQIFIAGPAGSGKRTQCKNIADRLGVVLISSGQVLTRGVESGSETSQLAHSYVSRGERVPDTLVSMIMKDRLSQSDAREKGWLVEGYPRNAQQAQAVEECGVIPQVFILLDLPEDLSFRRLEHRRYDPATNKEYHMLDNPPPAEDVALCERLVQRDADFHESIAKRLAQYYESIEGVKKHLGAVIEVVDARKSVEDVERDILAAVEKHRFR
Protein: NIF3-like protein 1 (Q9EQ80)
Organism: Mus musculus (Mouse)
Function: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12522100}. Nucleus {ECO:0000269|PubMed:12522100}. Note=Interaction with COPS2 may regulate localization to the nucleus. {ECO:0000269|PubMed:12522100}.
Interaction partners:
- GPN-loop GTPase 1
- Peptidyl-prolyl cis-trans isomerase-like 3
- COP9 signalosome complex subunit 2
Sequence:
MLSSAHLVPTSVQRAQSWICRSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMDEALQKKADFILSYHPPIFRPMKHITWKTWKECLVIRALENRVAVYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSRAPDYPTEGAHRLEFSVNRSQDLDKVMSTLRGVGGVSVTSFPARCDGEEQTRISLNCTQKTLMQVLAFLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLAIMIERIKTHLKLSHLRLALGVGRTLESQVKVVALCAGSGGSVLQGVEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSELQEMLGVHFENKINIILSETDRDPLRVV
Protein: D-serine dehydratase (EC 4.3.1.18) (D-serine deaminase) (DSD) (P53095)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Converts specifically D-serine to pyruvate and ammonia. May play a role in D-serine detoxification.
Interaction partners:
- Catabolic L-serine/threonine dehydratase
- Threonine dehydratase, mitochondrial
- Glyoxalase I
- NADPH-dependent methylglyoxal reductase GRE2
- Glutathione-independent glyoxalase HSP31
- Probable glutathione-independent glyoxalase HSP32
- Probable glutathione-independent glyoxalase SNO4
- Probable glutathione-independent glyoxalase HSP33
Sequence:
MSDVLSQYKGCSVRDLPTPNFVINEEKFDKNCTTMLNNVEKLSQECGVPIKFRAHVKTHKTAKGTLKQLGHGLPLAKRTTRAILVSTLKEAEELLNYQDRQCSDYIDDITYSLPCCVPEFIPLLSNLSRRVNNFQVFVDNIEHLENLKNFGRPASGKKWSVFIKVDMGTKRAGLAFDSPEFLSLLKKLTSSEIKEVIEPYGFYAHAGHSYSSTSINDTQNLLMEEVKAVNSAAKVLCSVDPQFDPSKLTLSVGATPTSNSLKLDNKSTLVKFITTQLVSTLEIHCGNYCMYDLQQVATGCVQDHELSGFVLGTVLSSYPSRGELLSNTGVMCLTREASSIKGFGICADLEHVLKSESFSREWYVARVSQEHGILRPIRNWNETTPLKLGSKIAVLPQHACITMGQFPYYFVVNSEGIVNDVWLPFQKW
Protein: Chromogranin-A (CgA) [Cleaved into: Pancreastatin; Beta-granin; WE-14; Catestatin; GE-25; Serpinin-RRG; Serpinin; p-Glu serpinin precursor] (P10354)
Organism: Rattus norvegicus (Rat)
Function: Strongly inhibits glucose induced insulin release from the pancreas.
Subcellular location: Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:12388744, ECO:0000269|PubMed:3896848}. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle {ECO:0000269|PubMed:29166604}. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. In pituitary gonadotropes, located in large secretory granules.; SUBCELLULAR LOCATION: [Serpinin]: Secreted {ECO:0000250|UniProtKB:P26339}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P26339}. Note=Pyroglutaminated serpinin localizes to secretory vesicle. {ECO:0000250|UniProtKB:P26339}.
Interaction partners:
- Secretogranin-1
- Secretogranin-3
- Secretogranin-2
- Gamma-enolase
- Synaptophysin
- Somatostatin
- Leucine-rich repeat-containing G-protein coupled receptor 5
- Carboxypeptidase E
- Gastrin
- Pro-glucagon
Sequence:
MRSSAALALLLCAGQVFALPVNSPMTKGDTKVMKCVLEVISDSLSKPSPMPVSPECLETLQGDERVLSILRHQNLLKELQDLALQGAKERAQQQQQQQQQQQQQQQQQQQQHSSFEDELSEVFENQSPAAKHGDAASEAPSKDTVEKREDSDKGQQDAFEGTTEGPRPQAFPEPKQESSMMGNSQSPGEDTANNTQSPTSLPSQEHGIPQTTEGSERGPSAQQQARKAKQEEKEEEEEEKEEEEEEKEEKAIAREKAGPKEVPTAASSSHFYSGYKKIQKDDDGQSESQAVNGKTGASEAVPSEGKGELEHSQQEEDGEEAMAGPPQGLFPGGKGQELERKQQEEEEEEERLSREWEDKRWSRMDQLAKELTAEKRLEGEDDPDRSMKLSFRARAYGFRDPGPQLRRGWRPSSREDSVEARGDFEEKKEEEGSANRRAEDQELESLSAIEAELEKVAHQLQALRRG
Protein: Transcription factor ABORTED MICROSPORES (Basic helix-loop-helix protein 21) (AtbHLH21) (bHLH 21) (Transcription factor EN 48) (bHLH transcription factor bHLH021) (Q9ZVX2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther. Binds E-box regions in the AHL16/TEK promoter.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Aspartyl protease UND
- PHD finger protein MALE STERILITY 1
- F-box/kelch-repeat protein At1g57790
- Mediator of RNA polymerase II transcription subunit 20b
- Dbj|BAA84809.1
- Geranylgeranyl transferase type-1 subunit beta
- Short-chain dehydrogenase reductase ATA1
- Protein DSS1 HOMOLOG ON CHROMOSOME V
Sequence:
MESNMQNLLEKLRPLVGARAWDYCVLWRLNEDQRFVKWMGCCCGGTELIAENGTEEFSYGGCRDVMFHHPRTKSCEFLSHLPASIPLDSGIYAETLLTNQTGWLSESSEPSFMQETICTRVLIPIPGGLVELFATRHVAEDQNVVDFVMGHCNMLMDDSVTINMMVADEVESKPYGMLSGDIQQKGSKEEDMMNLPSSYDISADQIRLNFLPQMSDYETQHLKMKSDYHHQALGYLPENGNKEMMGMNPFNTVEEDGIPVIGEPSLLVNEQQVVNDKDMNENGRVDSGSDCSDQIDDEDDPKYKKKSGKGSQAKNLMAERRRRKKLNDRLYALRSLVPRITKLDRASILGDAINYVKELQNEAKELQDELEENSETEDGSNRPQGGMSLNGTVVTGFHPGLSCNSNVPSVKQDVDLENSNDKGQEMEPQVDVAQLDGREFFVKVICEYKPGGFTRLMEALDSLGLEVTNANTTRYLSLVSNVFKVEKNDNEMVQAEHVRNSLLEITRNTSRGWQDDQMATGSMQNEKNEVDYQHYDDHQHHNGHHHPFDHQMNQSAHHHHHHQHINHYHNQ