wanglab/gogpt-training-data huggingface dataset:
Protein: Peroxisome proliferator-activated receptor alpha (Nuclear receptor subfamily 1 group C member 1) (K7DY57)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
- Retinoic acid receptor RXR-alpha-A
- Peroxisome proliferator-activated receptor alpha a.
- Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
- Peroxisome proliferator-activated receptor gamma
- histone acetyltransferase
- Fatty acid synthase
- Nuclear receptor coactivator 1.
- Nuclear receptor coactivator 2
- Acyl-coenzyme A oxidase
- Nuclear receptor corepressor 2
Sequence:
MVDMENRYRPPSPLDDSVLDSALFVRGMEELRDISQSMDEDALSSFEMTENQSGLGSGSESSTVLDALTPASSPSSGVYGCPVGQDEFTSTSLNLECRVCSDRASGYHYGVHACEGCKGFFRRTIRLKLEYDKCERRCKIQKKNRNKCQYCRFQKCLSVGMSHNAIRFGRMPQSEKLRLKAEILTGERDVKDDQKTLAKQIYEAYVKNFNMNKSKARTILTGKTSTPPFVIHDMETLQLAEQTFVAKMMGSCGGLLNKDPEVRIFHCCQCTSVETVTELTEFAKSVPGFSNLDLNDQVTLLKYGVHEALFAMLASCMNKDGLLVAYGSGFITREFLKSLRRPFSDMMEPKFQFAMKFNSLELDDSDLALFVAAIICCGDRPGLVNVPHIERMQESIVNVLHLHLKSNHPDHGFLFPKLLQKLVDLRQLVTEHAQLIQEIKKTEDTSLHPLLQEIYRDMY
Protein: Nuclear factor of activated T cells 1 (K7ER53)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRPSAQLRSCLWWRSRARTAIRSWAGRRWSCLATTSCRTPRSFSWRKPQMATMSGRWKRKLTGTCASRILWWLRSRHFGIRG
Protein: Uncharacterized protein C7D4.14c (O14269)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- NURS complex subunit red1
- Uncharacterized helicase C17H9.02
- Zinc finger CCCH domain-containing protein C337.12
- Uncharacterized RNA-binding protein C902.04
- NURS complex subunit pir2
- RNA binding exosome specificity factor Mmi1
- Enhancer of rudimentary homolog 1
- Polyadenylate-binding protein 2
- Poly
- Exosome complex exonuclease rrp6
Sequence:
MDAVEPSVEKEYKKIISFRDTVFEGKHQQFLVPNNVRLKFLRDRLHKSLKNFDSVKRKVEIANDEGNNKLLKSSPKAQTRDENTPSEFKNGGFSNRESMSENCFSKSSTNLPRLDINRDFNSLLNSQTKPEATGLMKEDITPVVNTSKQSSTGTQEESSKPEKSNKLLAKSTLSLYGNQAFNPSSVLPSNSSSTPKENKKNVNKETYQPNTFRRSPLKNDTGSVELSNLYMPSPPSSALPVSLVSAPSPPRATNVAVPCLKHLESSEQGNNLLINKAFTSPRLPSPPQSTRPSSTRFPSVPLSDEKNSIVSVKNEEPSVILGNQSPISDLHPYSPSWIPYPKELQSLQVNRIPELSLENNVMSTRDYKDIMPHPRPSAVLLDKPVSLDQTSHPFPHQNTYILPPGIRNSVDYDGTFLSRKSLPPYNGIHRLHESPSQFSNQSRYNWEPILENRSLLHLNRPPPIETHYSYESNNSSFSPYYHKRHRQISPYYPTSSVYGVYESPPHMSDSRISRQHMPLTHTTYEPSAPYYNDYELAEEIERRRHHSFYDY
Protein: ABC transporter G family member 9 (ABC transporter ABCG.9) (AtABCG9) (Probable white-brown complex homolog protein 9) (AtWBC9) (Q9SZR9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Together with ABCG31, involved in pollen coat deposition of steryl glycosides required for pollen fitness. Together with ABCG11 and ABCG14, required for vascular development by regulating lipid/sterol homeostasis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24112720, ECO:0000269|PubMed:24474628, ECO:0000269|PubMed:27634427}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein DETOXIFICATION 54
Sequence:
MDNQEVSMDVETPIAKTNDDRSLPFSIFKKANNPVTLKFENLVYTVKLKDSQGCFGKNDKTEERTILKGLTGIVKPGEILAMLGPSGSGKTSLLTALGGRVGEGKGKLTGNISYNNKPLSKAVKRTTGFVTQDDALYPNLTVTETLVFTALLRLPNSFKKQEKIKQAKAVMTELGLDRCKDTIIGGPFLRGVSGGERKRVSIGQEILINPSLLFLDEPTSGLDSTTAQRIVSILWELARGGRTVVTTIHQPSSRLFYMFDKLLLLSEGNPVYFGLGSNAMDYFASVGYSPLVERINPSDFLLDIANGVGSDESQRPEAMKAALVAFYKTNLLDSVINEVKGQDDLCNKPRESSRVATNTYGDWPTTWWQQFCVLLKRGLKQRRHDSFSGMKVAQIFIVSFLCGLLWWQTKISRLQDQIGLLFFISSFWAFFPLFQQIFTFPQERAMLQKERSSGMYRLSPYFLSRVVGDLPMELILPTCFLVITYWMAGLNHNLANFFVTLLVLLVHVLVSGGLGLALGALVMDQKSATTLGSVIMLTFLLAGGYYVQHVPVFISWIKYVSIGYYTYKLLILGQYTANELYPCGDNGKLRCHVGDFEGIKHIGFNSGLVSALALTAMLVVYRVIAYIALTRIGKTKSG
Protein: Solute carrier family 4 (anion exchanger), member 1, adaptor protein (A0A0J9YUT6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
XHPSAPSEPSCSKETKSHAPANEYKQDRDEPKKKKSPGPGKFPPILSSKYPEDDPDYCIWVPPEGQSGDGRTHLNDKYGY
Protein: PH domain-containing protein (D4YWB9)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSSRSRYQQARNRRLPPRHNQESRSTSSRRMGEEEIDRTFDQLYEELVSFGDSTKPTVTSNRSQRLRSEAPQSTVTTITVAATPATATLSIAECANTRLRSKSLTRLDEYEAEPISLKPSIERRYSKVDQLKKRSRKYQVNQEPEAADVLRPSVGRFSLTDHEIIIHGEEPYKRSSGRQRTPLTAQQTAELDDYFPSSNSMNSAPQTCSSSATPSLMSIIRQYENA
Protein: Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) (Q99NB2)
Organism: Rattus norvegicus (Rat)
Function: Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase 4
- Beta-1,4-galactosyltransferase 3
- Hexosyltransferase
- Hexosyltransferase
- Hexosyltransferase
- Beta-galactosidase
- Amphoterin-induced protein 2
Sequence:
MRVFVSSRRVKRWQFFHLFAICFILSFMVFWGPINNYIMSHMKSYSYRYLINSYDFVNDSLSLKHSSVQPHHPYLINHREKCQAQDVLLLLFIKTAPENYERRSAIRKTWGNENYVQSQLNANIKILFALGTPHPLKGKELQKRLIWEDQVYHDIIQQDFTDSFHNLTFKFLLQFGWANTFCPHARFLMTADDDIFIHMPNLIEYLQGLEQVGVRDFWIGHVHRGGPPVRDKSSKYYVPYEMYKWPAYPDYTAGAAYVVSNDVAAKIYEASQTLNSSMYIDDVFMGLCANKVGVVPQDHVFFSGEGKIPYHPCIYEKMITSHGHSQDLQDLWVEATDPKVKDISKGFFGQIYCRLIKIVLLCRLTYRNSYPCRAAFA
Protein: T-cell-interacting, activating receptor on myeloid cells protein 1 (OSCAR-like transcript-2 protein) (OLT-2) (B6A8C7)
Organism: Homo sapiens (Human)
Function: May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface. Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:26311901}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MIPKLLSLLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQHSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRNVSPGESEAFKPE
Protein: Metallothionein-1 (MT-1) (P52722)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Interaction partners:
Sequence:
MDPCECAKTGACNCGATCKCTNCQCTTCKKSCCSCCPSGCSKCASGCVCKGNSCGTSCCQ
Protein: Zinc finger protein 672 (Q499Z4)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MFATSGAVAAGKPYSCSECGKSFCYSSVLLRHERAHGGDGRFRCLECGERCARAADLRAHRRTHAGQTLYICSECGQSFRHSGRLDLHLGAHRQRCRTCPCRTCGRRFPHLPALLLHRRRQHLPERPRRCPLCARTFRQSALLFHQARAHPLGTTSDPAAPPHRCAQCPRAFRSGAGLRSHARIHVSRSPTRPRVSDAHQCGVCGKCFGKSSTLTRHLQTHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACGDCGRCFSESSTLLRHRRSHQGERPHACATCGKGFGQRSDLVVHQRIHTGEKPFACPECGRRFSDRSDLTKHRRTHTGEKPYRCELCGKRFTCVSNLNVHRRNHAGHKPHKCPECSKAFSVASKLALHRKTHLGERPAECAECGKCFSHSRSLSQHQRAHTRARTAAAVAIQSAVGTALVFEGPAEQEKPGFSVS
Protein: Mapk-regulated corepressor-interacting protein 1 (Granulin-2) (Protein FAM195B) (C9JLW8)
Organism: Homo sapiens (Human)
Function: The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition.
Subcellular location: Nucleus {ECO:0000269|PubMed:25728771, ECO:0000269|PubMed:26184334}. Cytoplasm, Stress granule {ECO:0000269|PubMed:26184334}.
Interaction partners:
- Protein LSM12
Sequence:
MTSSPVSRVVYNGKRTSSPRSPPSSSEIFTPAHEENVRFIYEAWQGVERDLRGQVPGGERGLVEEYVEKVPNPSLKTFKPIDLSDLKRRSTQDAKKS
Protein: RB1-inducible coiled-coil 1 (RB1-inducible coiled-coil protein 1) (E7FFM2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Autophagy-related protein 101
- Autophagy-related protein 13
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- Beclin 1-associated autophagy-related key regulator
- Beclin-1
- Unc-51-like autophagy-activating kinase 1a.
- ATG16 autophagy-related 16-like 1
- Nuclear receptor binding factor 2
- ATG16 autophagy-related 16-like 2
Sequence:
MKLYVFQVNNGSTLTFDTELAVQTVLDLKHAIQAKYKIAIQHQVLVVNGGECMVAERRVCSYSAGTDTNPIFLFNKEMILCDRAPTIPKTTFTIENEMELKVEESLMMPAVFHTVASRTQLALEMFEVAKKLCSFCERLVHDEHLQHQGWAAIMANLDDCTLSYQKLLLKFDTAYTNYQQDFEDIKLKLTKLGIAVSVMAKIPLLECLTRHSYRESLEKSSSPRPRIIDEDDDIEDEEIAEASTRSPALCPPDNLKNQKSPSPVSASSQASSSPQDRLKSSSSLKEALQEEEESPERMAMPSFNVTLLDWINVQDRPNDVESVVRKCFDSINRLDPRIIQPFLTECRETITKLDNQNMKAIKGLEDRLYALDQMIASCKKLVNEQKELAQGFLANQKRAENLKDTSVLPDLCLSHANQLMIMLTNHRKLLDIKQKCTTAKQELANNLQVRLKWCCYVMLHADQDGEKLQALLRLLTELLERVRVVEALSTVPQMYCLAVVEVVRRKMFIGHYRQWANALVKDGKNLYEAEKVKRETFGKLFRKSFLRNRLFRGLDSWPPSSFCTRKPRRFDFELPDISLSDLQYLKSCCPSEVQPYLRVPTLCDFEPLNQHVEVLHQLVQAAQSVDEMSQTITDLLNEQKNSYSQSAQRSTALTPRSESAIEITSTSTKTLSTLSLKAPDCQPLALPGPLEDLSPDSIDAQTFDFETIGHPSMDPVLQQGSLDLDSLAESPESDFMSAVNEFVIEENLLSPNPISDPTSPEMMVESLYSSVINAIDSKRIQDTTTLEKENSKIAAIKLSADRYRSAAEESQNNLRKVKEDLYHFRGLVLKEQRDFGFALKTMTTEVHNALSNVSYSHEEELKETQQTHLQSLKEDHEKQIRTLTEELEGNQKIVKDVQRAMLELEGLVERKEKEIYQLESERERSTQELQDLHKQAVQNLEEKILKQSEELKSALLSKDELAGQLEKLHFEIEHGQQKIRQEMKNAEKVHLQELETRLNQQHEAELQTFRLEKESALDKLVQDNLVKLRDLMDSHSAELKERDGRSKDMDARITELADARCKLEVEMALKEAEMEDMRLQYEEAKSTQEEVLKAEFATQTSTLKMQIDTLSLQLHQKNEEYEVGLAELRALMRLEKDHCISELVDRHEEESTLLRHEFSALKQKSQDVEKDCEERVLKIERDYKDRVDALQREKVEEQRAFQEKEDDLRTVIGDLQAENSLLSGRLEQERVEALLRVQEEKEEAVKAALQEALRDIQLQKEETETRLLGQIELLEKQLKDRQSTDTVASSAEQTEAGVQAETAVSLDSGQWTEERASLLAKLELLERTKNEEMQNLKTSLIAEQQTNFNTVLTREKLKKEQIISDLTEKLKNVMQQQEKDKGLIETLSEDRASILQEKKQLEEELNRLRSTVLVSSSFFPPNPIVPVVAEAHGACGPAQVDALSPSFPDPERLISMAAFRDEERVESAVEASMMTVHSDNSMLSEEKQRILILERTLHMKEEENKRLSQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVGPTLYFLHSESLTALDLKPATGATRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVPWNKKV
Protein: Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg-1) (Q62440)
Organism: Mus musculus (Mouse)
Function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:8713081}. Note=Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components.; SUBCELLULAR LOCATION: [Isoform 7]: Nucleus {ECO:0000269|PubMed:12359720}. Cytoplasm {ECO:0000269|PubMed:12359720}.; SUBCELLULAR LOCATION: [Isoform 8]: Nucleus {ECO:0000269|PubMed:12359720}. Cytoplasm {ECO:0000269|PubMed:12359720}.
Interaction partners:
- Lymphoid enhancer-binding factor 1
- Histone deacetylase 1
- Transducin-like enhancer protein 3
- Catenin beta-1
- Transcription factor 7-like 2
- Transducin-like enhancer protein 4
- Forkhead box protein G1
- Transcription factor HES-1
- B-cell CLL/lymphoma 9 protein
- Transcription factor 4
Sequence:
MFPQSRHPTPHQAAGQPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQAQHLSHGHGPPVPLTPHPSGLQPPGIPPLGGSASLLALSSALSGQSHLAIKDDKKHHDAERHRDRESGTSNSLLVPDSLRSTDKRRNGPEFSSDIKKRKVDDKDNYDSDGDKSDDNLVVDVSNEDPSSPHASPTHSPRENGIDKNRLLKKDASGSPASTASSGSSSSLKSKEVSLHEKANTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAMEPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYAGLHSMSPQMSAAAAAAAAAVVAYGRSPMVGFDPPPHMRVPSIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
Protein: Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A) (EC 6.3.5.7) (Q72DX1)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Interaction partners:
- Aspartyl/glutamyl-tRNA
- Aspartyl/glutamyl-tRNA
- Asparagine--tRNA ligase
- Glutamine--tRNA ligase
- biotin carboxylase
- Glutamate--tRNA ligase
- Aspartate--tRNA
- Glutamyl-Q tRNA
- tRNA-specific 2-thiouridylase MnmA
- GMP synthase
Sequence:
MSALHTLSLAAIRDALARREVRAEDAVLDCLARIETTEPRIDALLHLRAEAAIEEARALDAAGPDASRPLWGVPVTVKDALTTAGTPTTAGSRILEDFVPFYDAFAVQRLREAGAIILGKNNMDEFAMGSSTENSAYKPTRNPWDTARVPGGSSGGSAASVAAGQCFASLGTDTGGSIRQPASLCGCVGLKPTYGRVSRYGLIAYGSSLDQIGPMTRTVEDAAIVMGVIAGHDKRDSTCADRPVEDFAAALASRHDLAGVRIGVPAEFWGEGLSPEVATSCRAALDAARDLGATIVDVALPHTPQSIAAYYIVASAEASSNLARYDGVRYGKRAHAPEDLMDLYVRSRSEGLGDEVQRRIMLGTYVLSSGYYDAYYRKAAQVRRRILEDYRNAFATCDVICGPVSPVTAWPLGALTADPLQMYLMDVFTLSLNLAGLPGLSLPVGLGTESGMPVGIQLLGRSFDEATLLSVGNVLSRALPPLGSPAGLR
Protein: D-xylose reductases (Eurofung) (Q5AWY7)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- L-fuconate dehydratase
- D-xylose reductase [NAD
- Dihydrodipicolinate synthetase family protein
Sequence:
MSLGKKVTLNTGAQIPQLGFGTWQSAPGQVGEAVYQALKVGYRHLDLATIYQNQREVAEGIKRAYKDIPGLKREDIFITSKLWNTQHDPAVVEKALDDCLAELELDYLDLYLVHWPVAFKTGDNYFPLDESSDHPDGDVLIDDSISIVDTWKAMTKLPKEKARAIGVSNHTVEHLEAIINATGVVPAANQIERHPVLQSNDLIEYAAKKNIHITAYSAFGNNMFNIPLLVAHPEVKAVAEEASKRLGKTVTPAQVILNWSQEGGHSVIPKSVTASRIAENFQEVELTKEELAKVSKLGEERRRYNTPYVANKPRWNINIFGEEDEKPAKHKVIV
Protein: Methyltransferase type 11 domain-containing protein (P71794)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable sugar transferase
- Glycine--tRNA ligase
- Uncharacterized glycosyltransferase Rv1514c
Sequence:
MSTNPGPAEGANQVMAQEHSAGAVQFTAHNVRLDDGTLTIPESSRTLDESSWFISARGILETVFPGDKSHLRLADVGCLEGGYAVGFARMGFQVLGIEVRELNMAACNYIKSKTNLPNLRFVHDNALNIANHGLFDTVFCCGLFYHLENPKQYLETLSSVTNKLLILQTHFSIINRSDKWLRLPTTARQLTDRLLRRPAPVKFMLSAPTEHEGLPGRWFTEFSDDRSFGQRDTAKWASWDNRRSFWIQREHLLQAIKDVGVDLVMEEYDNLEPSIAESLLGGSYAANLRGTFIGIKTR
Protein: ATP-dependent DNA helicase XPD (SaXPD) (EC 5.6.2.3) (DNA 5'-3' helicase XPD) (Q4JC68)
Organism: Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Function: ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.
Interaction partners:
- Transcription factor E
- DNA-directed RNA polymerase subunit Rpo6
- TATA-box-binding protein
- DNA-directed RNA polymerase subunit Rpo12
- DNA-directed RNA polymerase subunit Rpo5
- DNA-directed RNA polymerase subunit Rpo2
- DNA-directed RNA polymerase subunit Rpo10
- DNA-directed RNA polymerase subunit Rpo3
- Flap endonuclease 1
- XPB/RAD25-related helicase
Sequence:
MLKLRDWQEKLKDKVIEGLRNNFLVALNAPTGSGKTLFSLLVSLEVKPKVLFVVRTHNEFYPIYRDLTKIREKRNITFSFLVGKPSSCLYAEKGAESEDIPCKYCELKGSIVEVKTDDSPLSLVKKLKKDGLQDKFCPYYSLLNSLYKADVIALTYPYFFIDRYREFIDIDLREYMIVIDEAHNLDKVNELEERSLSEITIQMAIKQSKSEESRRILSKLLNQLREVVLPDEKYIKVENVPKLSKEELEILADDYEDIRKDSLKQGKVNKIHIGSILRFFSLLSIGSFIPFSYSKRLVIKNPEISYYLNLLNDNELSIILMSGTLPPREYMEKVWGIKRNMLYLDVEREIQKRVSGSYECYIGVDVTSKYDMRSDNMWKRYADYLLKIYFQAKANVLVVFPSYEIMDRVMSRISLPKYVESEDSSVEDLYSAISANNKVLIGSVGKGKLAEGIELRNNDRSLISDVVIVGIPYPPPDDYLKILAQRVSLKMNRENEEFLFKIPALVTIKQAIGRAIRDVNDKCNVWLLDKRFESLYWKKNLKCLNANKMKL
Protein: Trafficking protein particle complex subunit 2-like protein (H3BP13)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
Interaction partners:
Sequence:
MAVCIAVIAKENYPLYIRSTPTENELKFHYMVHTSLDVVDEKISAMGKALVDQRELYLGLLYPTEDYKVYGYVTNSKVKFVMVVDSSNTALRDNEIRSMFRKLHNSYTDVMCNPFYNPGDRIQSRWALLSVSCHLLSVGHALPFWLPKCNHLENKGGKIFLSYEHHPPRAEVLKPQSPVSPHQLLHRSPAHKVDRVCVVWGVELAHLASQVCPVGTWGTCRTQGQAHGQWLSGITRPFVAT
Protein: T-complex protein 1 subunit theta (CCT-theta) (Q7ZU96)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MALHVPKAPGFAQMLKDGAKHYSGLEEAVFRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRMGLSVSEVIEGYEMACKKALEILPDCVCSSAKNLHDLEEATAMIRSAVMSKQYGNEDFLANLIAQACVSIFPESGSFNVDNVRVCKILGCGLNSSTMLHGMVFKKEAEGDVTSVKDAKIAVFSCPFDCTVTETKGTVLIKNADELMNFSKGEEDLMEAQVKAIADSGASVVVTGGKVADMALHYANKYKLMVVRLNSKWDLRRLCKTVGATALPRLTSPTPEEMGRCDSVYLSEVGDTQVVVFKHDKEDGAISTLVIRGSTDNLMDDIERAIDDGVNTFKVLVRDARLCPGAGATEIELAKHITSYGESCPGLEQYAIKKYAEAFEALPRALAENSGVKGNELISKLYATHHEGNKNSGFDIEGEGPAVRDMMEAGILDPYLVKYWGIKLATNAAITVLRVDQIIMAKPAGGPKAPQGKKDWDEDE
Protein: Probable diacylglycerol pyrophosphate phosphatase 1 (DGPP phosphatase) (EC 3.6.1.75) (Phosphatidate phosphatase) (EC 3.1.3.4) (Q9UUA6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the dephosphorylation of diacylglycerol phosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG).
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Diacylglycerol O-acyltransferase 1
- Nuclear elongation and deformation protein 1
- Uncharacterized acyltransferase C1851.02
- Phospholipid:diacylglycerol acyltransferase
- Lysophospholipid acyltransferase
- Phospholipase D1
- Putative lysophosphatidic acid:oleoyl-CoA acyltransferase
- Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.10
- CTP-dependent diacylglycerol kinase 1
- Glycerol-3-phosphate dehydrogenase, mitochondrial
Sequence:
MEAVGKHVKLFWNVYSDYAVLIAISLSYFVFDVLMLPFTRQFSLEDITISHPFALHEQVPTKYLGIICVFFPALVLYGFGKLRNNSLLFWKSLMGLLYSTMVCGLCVSLLKNAVGRPRPDFLARCQPFESTPKTGLVDVLSCSVPWSDKVLQDGFRSFPSGHTSFSFAGLGFLAIFLAGQLKMFRNKTSSWKVVVPLVPLSIASWIGLSRSQDYRHHKEDIAVGALFGFAIAYVVYRQLFPPLDHHNADILYVQAELDEGYTNVHSAGNSSATNAEQMV
Protein: Chaperone protein caf1M (Capsule protein fraction 1) (P26926)
Organism: Yersinia pestis
Function: Has a stimulatory role for the envelope antigen F1 secretion. It seems to interact with the subunit polypeptide and to prevent it from digestion by a protease.
Subcellular location: Periplasm.
Interaction partners:
Sequence:
MILNRLSTLGIITFGMLSFAANSAQPDIKFASKEYGVTIGESRIIYPLDAAGVMVSVKNTQDYPVLIQSRIYDENKEKESEDPFVVTPPLFRLDAKQQNSLRIAQAGGVFPRDKESLKWLCVKGIPPKDEDIWVDDATNKQKFNPDKDVGVFVQFAINNCIKLLVRPNELKGTPIQFAENLSWKVDGGKLIAENPSPFYMNIGELTFGGKSIPSHYIPPKSTWAFDLPKGLAGARNVSWRIINDQGGLDRLYSKNVTL
Protein: Angiopoietin-like protein 8 (Betatrophin) (Lipasin) (Refeeding-induced fat and liver protein) (Q8R1L8)
Organism: Mus musculus (Mouse)
Function: Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage. According to another study, not required for cleavage of ANGPTL3.
Subcellular location: Secreted {ECO:0000269|PubMed:22569073}.
Interaction partners:
- Angiopoietin-related protein 3
- Angiopoietin-related protein 4
- Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
- Lipoprotein lipase
- Angiopoietin-related protein 1
- Apolipoprotein A-V
Sequence:
MAVLALCLLWTLASAVRPAPVAPLGGPEPAQYEELTLLFHGALQLGQALNGVYRATEARLTEAGHSLGLYDRALEFLGTEVRQGQDATQELRTSLSEIQVEEDALHLRAEATARSLGEVARAQQALRDTVRRLQVQLRGAWLGQAHQEFETLKARADKQSHLLWALTGHVQRQQREMAEQQQWLRQIQQRLHTAALPA
Protein: Uncharacterized protein (Q388D4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNARGKGRPVKADEKDGTRSRPNKEEKQNQPLNEAKKRAPVGNKGGDSRPTDPPSTKGPLVQQKVRVPPSNAWARGGSSPSFLEIARGKNEVVVALPAPEPESEPEPEPVTFLNGGDTIAVTEDAVDSPAEVQDEVPITMEPPSNNEEPPYITIQEEIPVVDVPIEPQEEEMEQAPPVKYYVLEIDRIFEEQTVLPPRVTAVASENLCTFTFSGQPGEQPPQLGLPTTQSQHFYRAEPSAAARIFPNPVAVSDITRNTHWNPQPNHGVDLSSMGWRPLESSTRPFHQGMQYNSYGPPSQLPQRNFGPTMNRVRQPDLGEHPLRSLRDSTTINRQLGNGEGVW
Protein: Stabilizer of axonemal microtubules 4 (Protein phosphatase 1 regulatory subunit 32) (Q7Z5V6)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, cilium {ECO:0000250|UniProtKB:Q66HR9}. Cytoplasm {ECO:0000250|UniProtKB:Q66HR9}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q148A4}. Note=Localized to the cilia of polarized ependymal cells during development and at the adult stage. Preferentially locates between the peripheral microtubules of the axoneme and the ciliary membrane. {ECO:0000250|UniProtKB:Q66HR9}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
Sequence:
MMGKLPLGVVSPYVKMSSGGYTDPLKFYATSYCTAYGREDFKPRVGSHVGTGYKSNFQPVVSCQASLEALDNPARGEQAQDHFQSVASQSYRPLEVPDGKHPLPWSMRQTSSGYGREKPSAGPPTKEVRKVHFDTQEHGPQAITGLEPREVPLLHQQQGQDPLERENFRHGPRFMTSEYNSKYLRDPLDQPDFLQKKSIGAKEGSGFTKQSHQSPIVFQPPSQALPGDPALLPGQSVTKSDFLPKTHLHGDEFLPVLARGSKRETAFSRGNERILNPRVPPPCPEPSSVSHQQFQPLHRMQQTNVALLGRETVGKKEPTGFSLNNPMYVRSPCDPDRDQRYLTTYNQGYFENIPKGLDQEGWTRGGIQPQMPGGYALSQPVSCMEATPNPMESLRHLHPHVGRTLTSADPFYQNTPHSSRCVAHS