wanglab/gogpt-training-data huggingface dataset:
Protein: Mannose-6-phosphate isomerase 1 (EC 5.3.1.8) (Phosphohexomutase 1) (Phosphomannose isomerase 1) (PMI1) (Protein MATERNAL EFFECT EMBRYO ARREST 31) (Q9M884)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Phosphomannose isomerase involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. Involved in the ascorbic acid (AsA) biosynthesis. Required during the endosperm development.
Interaction partners:
- Phosphomannomutase
- Glucose-6-phosphate isomerase, cytosolic
- Glucose-6-phosphate isomerase 1, chloroplastic
- Probable hexokinase-like 2 protein
- Hexokinase-4
- Hexokinase-3
- Hexokinase-2
- Hexokinase-like 1 protein
- Hexokinase-1
- Probable fructokinase-5
Sequence:
MEIATVVKANGGCEADRRRLRRLRCSVKDYDWGKIGSDSLVYRVYAANSDYEIDPTRPYAELWMGTHESGPSYLEDADGSNGVTLRSWITENPKSLGNRVLEKWGCDLPFLFKVLSVARPLSIQAHPDKKLAKKMHKAHPNLYKDDNHKPEMALAYTQFEALCGFIPLQELKSVIRAIPEIEELVGSEEANQVFCITEHDEEKVKSVVRTIFTLLMSADADTTKKIVSKLKRRLHMESQERQLTDKERLVLKLEKQYPNDIGVISAFFFNYVKLNPGEALYLGANEPHAYLFGECLEVMATSDNVVRAGLTSKPLDIQTLCSMLSYKLGYPEILKGTRIRPYITRYLPPFEEFEVDLCDLPSGASTVFPSVPGPSLLLVLQGEGRMSTEASADGISMGDVLFVPADTEIHLRSSSDLKLYRAGINSRFLFPL
Protein: Solute carrier family 35 member E4 (Q6ICL7)
Organism: Homo sapiens (Human)
Function: Putative transporter.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MCRCPPEHHDGRMTSAEVGAAAGGAQAAGPPEWPPGSPQALRQPGRARVAMAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLVAALACHRGARRPMPGGTRCRVLLLSLTFGTSMACGNVGLRAVPLDLAQLVTTTTPLFTLALSALLLGRRHHPLQLAAMGPLCLGAACSLAGEFRTPPTGCGFLLAATCLRGLKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVLEAGVAPPPTAGDSRLWACILLSCLLSVLYNLASFSLLALTSALTVHVLGNLTVVGNLILSRLLFGSRLSALSYVGIALTLSGMFLYHNCEFVASWAARRGLWRRDQPSKGL
Protein: Chromodomain Y-like protein 2 (CDY-like 2) (Q9D5D8)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000269|PubMed:18450745}.
Interaction partners:
- Histone-lysine N-methyltransferase EHMT2
Sequence:
MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHLSKDKRVKSGKQAGASKLLRDARGLPVERLSHRPLEPGKSKPSSHKRKRVNSPLSRPKKGSSGKAPDRATKTVSYRTTPSGLQIMPLKKAQNGLENGDAGSEKDESHFGNGSHQPDLELNDQLGEQEASDCDGTHSALVENGVGSALTNGGLNLHSPVKRKLETEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEEVNEKECVMLKQLWSSSKGLDSLFSYLQDKIYEV
Protein: UNC-24 (G5ED76)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEYGMPEGSYDSVFTYAPYNDLDKMGYMGPARQGMMLGNKYGNFTYTRDYGVNMEDDIKPLSAIELLIFCVSFLFVVMTMPLSLLFALKFISTSEKLVVLRLGRAQKTRGPGITLVIPCIDTTHKVTMSITAFNVPPLQIITTDRGLVELGATVFLKIRDPIAAVCGVQDRNASVRTLANTMLYRYISKKRICDVTSSQDRRIISANLKDELGSFTCQFGVEITDVEISDVKIVKEGENMGMSALSSVAKSDAGQQLWQVIGPVFEDFAKECAAEEKAKENAPLVDLSDVPSTSAAGTSTDTPNIPSIDIDHLISVASLAMDEHLVRLIGRVFQINCKDIEPICIDLKHGSGSAYKGTSLNPDVVFETSLEVFGKILTKEVSPVTVYMNGNLKVKGSIQDAMQLKHLVERMSDWL
Protein: 4-vinyl reductase 4VR domain-containing protein (Q9HTG7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Membrane dipeptidase
- DgcA, Dimethylglycine catabolism
- Glycine betaine monooxygenase oxygenase subunit
- Electron transfer flavoprotein alpha/beta-subunit N-terminal domain-containing protein
- DgcB, Dimethylglycine catabolism
- Sarcosine oxidase gamma subunit
- Sarcosine oxidase delta subunit
- Glycine betaine monooxygenase reductase subunit
- Sarcosine oxidase subunit beta subunit beta)
- Glutathione-independent formaldehyde dehydrogenase
Sequence:
MAKHAPQLPIEVDSETGVWTTDALPMLYVPRHFFVNNHMGIEEVLGADAYAEILYKAGYKSAWHWCEKEAECHGLEGVAVFEHYMKRLSQRGWGLFEIERINLEEGTAEVRLRHSAFVYVYGKVNRKVDYMFTGWFAGAMDQILAARGSSLRTVAEQVYSGAEDGHEDGLFVVKPL
Protein: Probable inactive receptor kinase At5g10020 (Q0WR59)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein
Sequence:
MSHFLTFCFLSLLLLLHGANAVTETELRSLLEFRKGIRDETSHQRISWSDTSSLTDPSTCPNDWPGISCDPETGSIIAINLDRRGLSGELKFSTLSGLTRLRNLSLSGNSFSGRVVPSLGGISSLQHLDLSDNGFYGPIPGRISELWSLNHLNLSSNKFEGGFPSGFRNLQQLRSLDLHKNEIWGDVGEIFTELKNVEFVDLSCNRFNGGLSLPMENISSISNTLRHLNLSHNALNGKFFSEESIGSFKNLEIVDLENNQINGELPHFGSQPSLRILKLARNELFGLVPQELLQSSIPLLELDLSRNGFTGSISEINSSTLTMLNLSSNGLSGDLPSSFKSCSVIDLSGNTFSGDVSVVQKWEATPDVLDLSSNNLSGSLPNFTSAFSRLSVLSIRNNSVSGSLPSLWGDSQFSVIDLSSNKFSGFIPVSFFTFASLRSLNLSRNNLEGPIPFRGSRASELLVLNSYPQMELLDLSTNSLTGMLPGDIGTMEKIKVLNLANNKLSGELPSDLNKLSGLLFLDLSNNTFKGQIPNKLPSQMVGFNVSYNDLSGIIPEDLRSYPPSSFYPGNSKLSLPGRIPADSSGDLSLPGKKHHSKLSIRIAIIVASVGAAIMILFVLFAYHRTQLKDFHGRNRFTDQATTRDTKFGRSSRPSLFNFSSNVEQQSSSLSFSNDHLLTANSRSLSGIPGCEAEISEQGAPATSAPTNLLDDYPAASGRKSSSGGSPLSSSPRFSDQPVMLDVYSPDRLAGELFFLDVSLKLTAEELSRAPAEVLGRSSHGTLYKATLDNGHMLTVKWLRVGLVRHKKDFAREAKKIGSLKHPNIVPLRAYYWGPREQERLLLSDYLRGESLAMHLYETTPRRYSPMSFSQRLKVAVEVAQCLLYLHDRAMPHGNLKPTNIILSSPDNTVRITDYCVHRLMTPSGVAEQILNMSALGYSAPELSSASKPIPTLKSDVYAFGVILMELLTRRSAGDIISGQTGAVDLTDWVRLCDQEGRRMDCIDRDIAGGEEFSKGMEDALAVAIRCILSVNERPNIRQVLDHLTSISA
Protein: 2-deoxystreptamine glucosyltransferase (EC 2.4.1.284) (2-deoxystreptamine N-acetyl-D-glucosaminyltransferase) (EC 2.4.1.283) (Kanamycin biosynthesis protein F) (Q65CC1)
Organism: Streptomyces kanamyceticus
Function: Glycosyltransferase involved in the biosynthesis of kanamycin by mediating conversion of 2-deoxystreptamine (2-DOS) to 2'-N-acetylparomamine using UDP-alpha-D-glucose as sugar donor. Can also accept UDP-alpha-D-glucosamine, but with a much lower activity compared to UDP-alpha-D-glucose.
Interaction partners:
Sequence:
MQVQILRMSRALAELGVRQQVLTVGFPGLPRVRRDSENLVVRITRAPLPRLRSRITGLVGLNQAWLAAALTECVKLRRRWPADLIQVHLDGQLWALLAGPVAARLVGVPYTVTVHCSRLAVYQPMSTVDRIQHPLVTAVERWALRRAAGITTLTERTATVLAAELGAAQRVIDVVPDAVDPDRAEAAPAEVERLKKRFGLPQEGGPVIGFVGRIAHEKGWRHAVQAVAELADAGRDFTFLVVGDGPQRADMEAAVAEAGLTDRFVFTGFLPNDEIPAVMTALDVLLMPSVHEELGGSAVEAMLAGTPVAAYGVGGLCDTVGKVTPSLLAAPGQVAELARTVKRVLDDPAPVLAELRAGREWLADEFGVHHAAGLALAHYERVLGKER
Protein: E protein transcript B (Q9N2Q2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MYENFFQDNQVNYFGVIGVGKDDQVEITSNAFSHNKGGFPNIEIRNVLRVFLREKFLTGADYKLLVEDVTQLSVFSNALQKTNLDCSLKRIKELNLMKNAFNPGVAKYGINLRIEDSNINQLGIFGVSMGKVSLLRCHIDMIMSNAFDVTSIKELIIEGCNIEVIESQALTNKLHSDKVAIVDTVIGTIEGQAISQSGITTMIMFGNTITKIRSNAIQIVAISLFIRNNSMSHVEPNWLSVSQADQVEIANNRFEDYGRCELNIGSSNCSFRNNILQNPQSGSLNFTCRVHQVRVGTECSCNKSWLSELTDHDLESEIMCQVAKRDANCFNATNTDVRRYVNEACGSNVTRYCMGGQWVTKAVSDHSSDSSKLTIGMIALEIVILTLLLVAIVCVLAKNCGSGSCAPAGGQSTDNCLIEEDIRNSLRQLALHSESNKTRKAILKLINGHLSKGECNDRILFIVDNMPQNQAIESLLFRHISQSHMEPSDSEAYASTALTANATAPPLPPSTDSSEPIYQELDQQRLIIDDKYSLPLNSDEDPPYSEPSNMMNTNDMPPAYQYATPMRILPCHQMQHQQPSTTANYAIPVWRSTPSATPTSRPPSGSQEGSATATAPRAVKDLRQALQNSPQFHPNQLTSTRNQRQILQILPPLQPPPYTQRSQVRGQRRRSFECLDGAASLAPWSTWTPARITLAAVM
Protein: Misshapen, isoform H (M9PBJ7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQNNFKPSDHLDVLAAQLSELGVVFSQQPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPDDDDQAGDRTLIMKRNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEYQAAISSSVHSTPSKSFIASSGSGGLGLGGGTVVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSITNLLHKSASSSSANLHHLTPCSSTSSASISNPLPPHAYALQQKQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW
Protein: Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3) (Q8R4F0)
Organism: Mus musculus (Mouse)
Function: Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity. Mediates release of Ca(2+) from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway (By similarity). Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells. Proposed to play a critical role at the cochlear stereocilia ankle-link region during hair-bundle growth. Involved in the regulation of autophagy. Through association with GABARAPL2 may be involved in autophagosome formation possibly providing Ca(2+) for the fusion process. Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events. Possible heteromeric ion channel assemblies with TRPV5 show pharmacological similarity with TRPML3 (By similarity).
Subcellular location: Early endosome membrane {ECO:0000250|UniProtKB:Q8TDD5}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F6RG56}. Late endosome membrane {ECO:0000269|PubMed:17989217}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F6RG56}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:24269818}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F6RG56}. Cell projection, stereocilium membrane {ECO:0000269|PubMed:18801844}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F6RG56}. Note=Recycles between the plasma membrane and intracellular compartments by a dynamin-dependent endocytic pathway (By similarity). In the cochlea located at the base of stereocilia near the position of the ankle links. {ECO:0000250|UniProtKB:Q8TDD5, ECO:0000269|PubMed:18801844}.
Interaction partners:
- Mucolipin-2
- Mucolipin-1
- Transient receptor potential cation channel subfamily V member 5
Sequence:
MANPEVLVSSCRARQDESPCTFHPSSSPSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSEVYDQIIFAVTQYLQLQNISVGNHAYENKGTKQSAMAICQHFYRQGTICPGNDTFDIDPEVETECFLVEPDEASHLGTPGENKLNLSLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIKECKDWHVSGSIQKNTHYMMIFDAFVILTCLASLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIISDILTIVGSVLKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNRVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSGKYRLEDDPPGSLLCCCKK
Protein: Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (Q54KI3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Methylates arginine residues in proteins such as small nuclear ribonucleoproteins or histone H2A/H4.
Interaction partners:
- WD40 repeat-containing protein
- Methylosome subunit pICln
- Histone H4
- Serine/threonine-protein kinase rio1
- Protein arginine N-methyltransferase 1
- WD40 repeat-containing protein
- Protein arginine N-methyltransferase 2
- Probable flavin-containing monoamine oxidase B
- Probable flavin-containing monoamine oxidase C
- FACT complex subunit SSRP1
Sequence:
MINSAQYEFSCGVELESVDIQLDIERAYDLEYQFIMTSISHPRFNRDFTKASIGNSFSNKVAFTRSDTLLQSNYWRSSIVGKTSTNGIDLDSIDPTIRSNSVKTLKQEISWAAHLSLPSILLPTPSFNSTNYAQVVNQSLQSLSYMKVWIRIPLVSPKSQLLNKFDYYQDHNTSGGSGNNLVDNDNPWEWWNNFRLLCNQHPNLSAVLEMTSDLPSKEQLQQWLGEPVKCVIIPTSVFLTNKAGFPTLSKAHQQFLLQLFNYNIQFVVSGASMDTLKDYKTYLKFLHTNQNPLTQEEYFEMPYLDFLQAPLQPLMDNLESQTYEVFEKDPIKYKQYQNAVRLALLDLDKKDSKDDPIIIMVVGAGRGPLVNSSIQASIEANKFVKVFAVEKNPNAIVTLRNRIIMEGWEEIVTVIDSDMRDWNTEYRADIMVSELLGSFGDNELSPECLDGAQRYLKKDTGISIPTWYTSYIAPISSSKLFNEVTAYGDLKHSETPYVVKPHNFHQLAESKPLFTFSHPNRDEIIDNSRYESLEFELTIPSTTCHGFIGYFDCCLYKDVHISINPSNFSTGMFSWFPIYFPLKQPVYFSNGNLNNNNNNNIKAKCAFWRNVSKSKVWYEWCLLSPTITPIQNVGGRSYYIGL
Protein: Neuropilin and tolloid-like, isoform B (RE42119p1) (G4LU05)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Glutamate receptor IIB
- Glutamate receptor IIC
- Glutamate receptor IIA
- FI04462p
- FI23915p1
- Glutamate receptor IB, isoform B
- Glutamate receptor 1
- Glutamate [NMDA] receptor subunit 1
- NMDA receptor 2, isoform C
Sequence:
MRRRGSTCSAQQPQQRPHKQQQQQQQQNQRLIPGQRCSLLMLLIVGQAVYASAGSEIIANRSASAGESLIMLSNFTVATPPPAPRFTSPFREQDVAEGEELAGGGQVDWLDEQHPLTISRPPRAGRSERQAEEDQVDRCRLFVEGDPTKNELYSPEYPNLYPKNINCTRVITAPKGQIIRLDFRNSFNIEAKEGCKFDFLEIRDGQYGFSTLIGKFCGTDFPPEITSKERYLWLHFHSDETIEYTGFSAVYEYLDRSRDAPSTDLNCTIDKGGFEGFINSTDVPAEIWEQVNRNKIALDCIWRIQVKENWKIFLKFLDFKLSKPNDCQTNFLDIFPEQTVMPLRVKNFCGSAGESITAESNILHLRFYADQTAINSTFGILFTAFRERGAACTEDEYDCEDATCISKDLKCNNLDNCKFRWDEEGCTSEAAGQSEHVVIIVIVFGLILGGMVITFIVNCIRKIIRDQKIIREHIRESKESKLDEMGRNSKGRSRENISRQKHSQTSLQILDDVSNRYYREAVPLSSQSSKADFKEKEHSILRRHADMTQTSLCGVGEDDGESSSTTTATHEMMTKAAMSAVPSNACDMGCQTRESLFVNSPGIGPSAGPGVGVAVGIGIAVAPGGGVATLMRQKSSSSSLGVGGGAGGGAMMMPPPPPRFFSTFGYEPSGSPAVATLTRRSMHQQQQHPQMPRQESMEMEERHSGRSHYGGLLVTSTAKQPQEICHHHHQHQQQHQQQHQQQQQQQQQQQQQQQRMHHAHPHPPSIAARLPAMKGHGTVMGQTTILPGGNKQQQQHQQKNEESKVFIDIRNSAPDVIIMTSH
Protein: Very-long-chain aldehyde decarbonylase GL1-6 (EC 4.1.99.5) (Protein GLOSSY 1-6) (Q6K3D8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes. Core component of a very-long-chain alkane synthesis complex.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:F4HVY0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F4HVY0}.
Interaction partners:
- Very-long-chain aldehyde decarbonylase GL1-5
- Very-long-chain aldehyde decarbonylase GL1-2
Sequence:
MASKPGPLTQWPWHNLGNYKYALVAPSAAYSTYRFVTASSAAERDLLNFMVFPMLLLRLLYGQLWITVSRHQTARSKHKIVNKSLDFEQIDRERNWDDQIILTALVFYLVSATMPQAQVAPWWSTKGMVVTAVLHAGPVEFLYYWLHRALHHHWLYARYHSHHHASIVTEPITSVIHPFAEEVVYFVLLAIPILSTVATGTVSVVTANGYLVYIDFMNYLGHCNFELVPKCLFHVFPPLKYLLYTPSFHSLHHTQFRTNYSLFMPVYDYIYGTTDKSSDELYERTLQGRDEAAWRPDVVHLTHLTTPESVFHNRLGFAAVASNPLGAAASGHLLRAASAVASPLLSLFASTFRSEANRLDKLNIETWVIPRFTSHYTSKSDGYKVSRLIEKAVSDAEASGARVLTLGLLNQGYDLNRNGELYVVRKPSLKTKIVDGTSLAVAAVLNMIPQGTKDVLLLGNANKISLVLTLSLCKREIQVRMVNKELYECLKQQLQPEMQEHLVLSCSYSSKVWLVGDGVTDEEQMKAQKGSHFVPYSQFPPNKARNDCVYHCTPALLVPESFENLHVCENWLPRRVMSAWRAAGIVHALEKWDGHECGGRVTGVQKAWSAALARGFRPYDDHHHPGITHDGRGGL
Protein: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (23PGA-independent) (BPG-independent PGAM) (Phosphoglyceromutase) (iPGM) (EC 5.4.2.12) (Q9X519)
Organism: Geobacillus stearothermophilus (Bacillus stearothermophilus)
Function: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate (2-PGA) and 3-phosphoglycerate (3-PGA).
Interaction partners:
Sequence:
MSKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVKGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEKFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIVK
Protein: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) (Malate dehydrogenase [quinone] iron-sulfur subunit) (EC 1.1.5.-) (Q007T0)
Organism: Sus scrofa (Pig)
Function: Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9YHT2}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9YHT2}; Matrix side {ECO:0000250|UniProtKB:Q9YHT2}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- Fumarate hydratase, mitochondrial
- Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Citrate synthase, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
Sequence:
MAAVVAVSLKRWFPATTLGGACLQACRGAQTAAATAPRIKKFAIYRWDPDKTGDKPHMQTYEIDLNNCGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLDKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTGTCPKGLNPGKAIAEIKKMMATYKEKKASA
Protein: Trypsin inhibitor 2 (MCoTI-II) (Trypsin inhibitor II) (P82409)
Organism: Momordica cochinchinensis (Spiny bitter cucumber) (Muricia cochinchinensis)
Function: Inhibits trypsin; probably participates in a plant defense mechanism.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
SGSDGGVCPKILKKCRRDSDCPGACICRGNGYCG
Protein: Vascular endothelial growth factor D (VEGF-D) (c-Fos-induced growth factor) (FIGF) (O35251)
Organism: Rattus norvegicus (Rat)
Function: Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-3 (Flt4) receptor (By similarity).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor C
- Neuropilin-2
- Angiopoietin-1 receptor
- Neuropilin-1
- Macrophage colony-stimulating factor 1 receptor
- Platelet-derived growth factor C
- Platelet-derived growth factor receptor beta
Sequence:
MYGEWAAVNILMMSYVYLVQGFSIEHRAVKDVSLERSSRSVLERSEQQIRAASTLEELLQVAHSEDWKLWRCRLKLKSLANVDSRSTSHRSTRFAATFYDTETLKVIDEEWQRTQCSPRETCVEVASELGKTTNTFFKPPCVNVFRCGGCCNEESVMCMNTSTSYISKQLFEISVPLTSVPELVPVKIANHTGCKCLPTGPRHPYSIIRRSIQIPEEDQCPHSKKLCPVDMLWDNTKCKCVLQDENPLPGTEDHSYLQEPALCGPHMMFDEDRCECVCKAPCPGDLIQHPENCSCFECKESLESCCQKHKMFHPDTCRSMVFSLSP
Protein: Proteasome subunit beta (A0A140VK45)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU004203}. Nucleus {ECO:0000256|RuleBase:RU004203}.
Interaction partners:
Sequence:
MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD
Protein: Synaptotagmin binding, cytoplasmic RNA interacting protein variant (Q59GL1)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
STRFPQPDTIGQDFSASAQRGGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ
Protein: RAS small monomeric GTPase RasA (E9QX28)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- Adenylate cyclase
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase
- Ras-like protein B
- Rho GTPase activator Rga, putative
- GTPase activating protein
- Rho guanyl nucleotide exchange factor, putative
Sequence:
MASKFLREYKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDDEVALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSITSRQSFEEIMTFQQQILRVKDKDYFPIIVVGNKCDLEKERAVSQQEGEALARQFGCKFIETSAKSRINVENAFYDLVREIRRYNKEMSSYPSGSGAAGTRAPEGKMDVSEPGDNAGCCGKCVIM
Protein: fructose-bisphosphate aldolase (EC 4.1.2.13) (H3BUH7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIG
Protein: Uncharacterized membrane protein C23A1.05 (O42843)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Palmitoyltransferase erf2
- Serine palmitoyltransferase 2
- Serine palmitoyltransferase 1
- Ras modification protein erf4
Sequence:
MGNPVVIKAKKDYDCVFEPEPMSWLRLQYYRYQVTAGTYLFTYKEAFVFNTVVFIIVFLTGWAAKSIIVKLLPSLWRLSTLIPSFFASFFMSLLGKDASSQ
Protein: DNA damage-binding protein 1b (UV-damaged DNA-binding protein 1b) (DDB1b) (O49552)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness (By similarity). Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB) (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Cullin-4
- Putative cullin-like protein 4
- Cullin-like protein 5
- Protein DAMAGED DNA-BINDING 2
- DET1- and DDB1-associated protein 1
- RING-box protein 1a
- Transducin/WD40 repeat-like superfamily protein
- Protein ALTERED SEED GERMINATION 2
- WD repeat-containing protein ATCSA-1
- Light-mediated development protein DET1
Sequence:
MSVWNYAVTAQKPTCVTHSCVGNFTSPQELNLIVAKSTRIEIHLLSPQGLQTILDVPLYGRIATMELFRPHGEAQDFLFVATERYKFCVLQWDYESSELITRAMGDVSDRIGRPTDNGQIGIIDPDCRVIGLHLYDGLFKVIPFDNKGQLKEAFNIRLEELQVLDIKFLYGCTKPTIAVLYQDNKDARHVKTYEVSLKDKNFVEGPWSQNNLDNGADLLIPVPSPLCGVLIIGEETIVYCSANAFKAIPIRPSITKAYGRVDLDGSRYLLGDHAGLIHLLVITHEKEKVTGLKIELLGETSIASSISYLDNAVVFVGSSYGDSQLIKLNLQPDAKGSYVEILEKYVNLGPIVDFCVVDLERQGQGQVVTCSGAYKDGSLRIVRNGIGINEQASVELQGIKGMWSLKSSIDEAFDTFLVVSFISETRILAMNIEDELEETEIEGFLSEVQTLFCHDAVYNQLVQVTSNSVRLVSSTTRELRNKWDAPAGFSVNVATANASQVLLATGGGHLVYLEIGDGTLTEVKHVLLEYEVSCLDINPIGDNPNYSQLAAVGMWTDISVRIFVLPDLTLITKEELGGEIIPRSVLLCAFEGISYLLCALGDGHLLNFQLDTSCGKLRDRKKVSLGTRPITLRTFSSKSATHVFAASDRPAVIYSNNKKLLYSNVNLKEVSHMCPFNSAAFPDSLAIAREGELTIGTIDDIQKLHIRTIPIGEHARRICHQEQTRTFAISCLRNEPSAEESESHFVRLLDAQSFEFLSSYPLDAFECGCSILSCSFTDDKNVYYCVGTAYVLPEENEPTKGRILVFIVEEGRLQLITEKETKGAVYSLNAFNGKLLASINQKIQLYKWMLRDDGTRELQSECGHHGHILALYVQTRGDFIAVGDLMKSISLLIYKHEEGAIEERARDYNANWMTAVEILNDDIYLGTDNCFNIFTVKKNNEGATDEERARMEVVGEYHIGEFVNRFRHGSLVMKLPDSDIGQIPTVIFGTVSGMIGVIASLPQEQYAFLEKLQTSLRKVIKGVGGLSHEQWRSFNNEKRTAEAKGYLDGDLIESFLDLSRGKMEEISKGMDVQVEELCKRVEELTRLH
Protein: Limb region 1 protein homolog (Differentiation-related gene 14 protein) (Q8WVP7)
Organism: Homo sapiens (Human)
Function: Putative membrane receptor.
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Zona pellucida sperm-binding protein 2
- Sonic hedgehog protein
- Motor neuron and pancreas homeobox protein 1
- RING finger protein 32
- Nucleolar MIF4G domain-containing protein 1
Sequence:
MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRISLFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISVLLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAIVTTLCLVRKFTSAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL
Protein: Uncharacterized protein (Q38FW5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHSRRIFGSAAIPLAMYTKLRICSQAQARRRLPSLVPLLPAMATATRSVIPLVQSTTPTMPMLETAEFDPVLLSNYLECIAPMRVGFLRLMELWGIGRMVMSCFFPKMR