wanglab/gogpt-training-data huggingface dataset:
Protein: Autism susceptibility gene 2 protein (Q8WXX7)
Organism: Homo sapiens (Human)
Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The PRC1-like complex that contains PCGF5, RNF2, CSNK2B, RYBP and AUTS2 has decreased histone H2A ubiquitination activity, due to the phosphorylation of RNF2 by CSNK2B. As a consequence, the complex mediates transcriptional activation. In the cytoplasm, plays a role in axon and dendrite elongation and in neuronal migration during embryonic brain development. Promotes reorganization of the actin cytoskeleton, lamellipodia formation and neurite elongation via its interaction with RAC guanine nucleotide exchange factors, which then leads to the activation of RAC1 (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:25519132}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0A087WPF7}. Cell projection, growth cone {ECO:0000250|UniProtKB:A0A087WPF7}. Note=Detected both in cytoplasm and nucleus. Colocalizes with RAC1 at actin-rich growth cones. Detected on the promoter region of actively transcribed genes. {ECO:0000250|UniProtKB:A0A087WPF7}.
Interaction partners:
- Polycomb group RING finger protein 5
- RING1 and YY1-binding protein
- YY1-associated factor 2
- Casein kinase II subunit alpha'
- Polycomb group RING finger protein 6
- Polycomb group RING finger protein 3
- Calcium-dependent secretion activator 2
- E3 ubiquitin-protein ligase RING2
- DDB1- and CUL4-associated factor 7
- Casein kinase II subunit beta
Sequence:
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR
Protein: SUPPRESSOR OF ABI3-5 (REQUIRED FOR SNC4-1D protein 1) (Splicing factor SUA) (F4JCU0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Splicing factor that controls alternative splicing of the developmental regulator ABI3. Reduces splicing of a cryptic intron in ABI3, leading to a decreased in ABI3-beta transcript. Regulates the splicing of the receptor-like kinase SNC4/LRKL-2.6.
Subcellular location: Nucleus {ECO:0000269|PubMed:20525852}.
Interaction partners:
- DNA-damage-repair/toleration protein 111
- Splicing factor U2af large subunit A
- Protein SUPPRESSOR OF NPR1-1 CONSTITUTIVE 4
- DEAD-box ATP-dependent RNA helicase 32
- Polypyrimidine tract-binding protein homolog 1
- Nucleolar protein
- G-patch domain-containing protein 1
- At4g28200
- Bystin
- rRNA biogenesis protein RRP36
Sequence:
MDPSRYGRQQEWDNNSAPEGYGTQHDPNHRFGVSYDDGYPDERLMRDDVYNYPPGHNTLGDLPQSRKRNYEENYPSELRRQEKPYIDSNYAADYYHDSEAGSRNGHYRDHEHERSSRYDGCDDYSCNDNNYRSKNYHHSRDDGREKDYDYTRRSYDSEYERASVRDGSRKSRDPQDRERNSRDREWDSRDREWDKRCYSRERDESPHKRYEKSRSRSTGRGEFSRSRSPRGRSHGRSYREDSYEGDHWNESERRREYEDRHNQDHFSATPSATVVVKGLSMKSTEEDLYQILAEWGPLHHVRVIREQNSGISRGFAFIDFPTVDAARTMMDRIEHDGIVLDGRKLMFHYSQPTGRAGVSRRQEHASRRSYGGSRNMIVPTDWICTICGCINFARRTSCFQCNEPKTKDSPSADVGLSNSAAGKRISETGPTHVLVVRGLDEDADEEMLRYEFSKHAPIKDLRLVRDKFTHVSRGFAFVHFYSVEDATKALEATNRTALERNGKILRVAYAKSVHGSGTGISAPSHSNNLAAAAIEAATFSQQYDGVGWAPKEYNTGEKQNTGGQAQGVGEIESQKGTSAPQSGYVWDEASGYYYDAASGYYYDGNSGLYYDSNSGLWYSYDQQTQQYVPCPDQNNESKVTENQPDSAKKEKSSQQKVIISAATTPNVEKVLSLPDAVQAAAAAAIASEKREKERVKEIKLASKTSLLASKKKMSNVLTMWKQRSHETQIQRPSPSLGDNPPTVSAEARSSFSTGQSMGKLKSDVIIAKERSTSNHGVSALTTAESSSSSTTGGTLMGVMRGSFGGTLGGASSSASVQMPPILPSASPASVSVSGSGRRRFSETPTAGPTHREQPQTSYRDRAAERRNLYGSSTSSGNDVIDSSEDLMGLRKGSSDPTPFPPGVGGRGITTSTEVSSFDVITEERAIDESNVGNRMLRNMGWHEGSGLGKDGSGMKEPVQAQGVDRRAGLGSQQKKVDAEFEVQPGDTYRTLLHKKALARFRDMSDNN
Protein: SAM domain-containing protein (Q9U2L2)
Organism: Caenorhabditis elegans
Interaction partners:
- ANK_REP_REGION domain-containing protein
- Serine/threonine-protein kinase nekl-3
- Serine/threonine-protein kinase nekl-2
- Ubiquitin-like domain-containing protein
- Ubiquitin-like domain-containing protein
- non-specific serine/threonine protein kinase
- NECAP PHear domain-containing protein
Sequence:
MSFRVRFSQERPGVTYVPSSRSGNTDLFNDIFSKPMPIIRNEDHVLMDACTAASIGDENKLKELMKINPNTMIMKNHDGWTPLLYAAYLGHNSVAAFLLDNGAKVDDSTESRWQTPLMMASACGNISVVRLLLGRGANPRLCDKEKRQAIHYASSCCQNVVVDTLLAAGCDPNAADSEGTTPVHEAAMAGHEITFIALLEKGGNLELKNAKGENAAALACDNNKILQLISEHQAEIAKQSSKTGNRGPRRLSELLEEMDLSRYIDQFKHENVDLEVFFELKEQDFVDMNIAYGPKKRMLDVIERYKKTGVIRSDAFDAPQGTAMSTKGSSTRESSEKTTATLKSIKELNQETKKSVMTALESLGSGQDKVRAQLISILNNVETISLKVSSHV
Protein: Eukaryotic translation initiation factor 5B (Translation initiation factor IF-2) (Q5A782)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS19
- Eukaryotic translation initiation factor 1A
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein eS12
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS2
Sequence:
MAKKGKKAAQAGGDFWDDEDMAQDQPQAEEFGTPAEPESQEASAEDVSGDLLSSIRKNKQKKAEKQENEKANVNNGDAPKLLSKKEKEKLKKEAEKQKKKELAQKKKAQQATKKEQIKEANKQNAGSAVTASSASATPEPEENESSAASEQNEAPKAKPAKKGKKAPAGLAALKKQLELKKQLEEEQRRLEEEEEQRRLEEERLAAEEEAKKEAARAAKKERERLKKEQLKAEGKLLTKKQKEEKKLQERRRQQLLQAGNVSVAGLSKTEEGDAPKPKKVVYTKKKSTKPKTFIQKPVPSKAPVKKDDGEDEALVDDWEKMALDDDAPVADDWEAALADEGDEEVGEAEEEDEEVGEDEDTIVEDEQEKKAKEEAARKAKEESARKAKEEAARKAQEEEKSKQLAAQKKAASPSEKDLRSPICCILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATYFPVDAIKQKTAVMAKYEKQTFDVPGLLIIDTPGHESFTNLRSRGSSLCNIAILVIDIMHGLEQQTLESIRLLRDRKAPFVVALNKIDRLYDWKEIPNNSFRDSFAKQTKSVQAEFENRYEQIKLALAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKRMSKQLMYLSKVAATILEVKVVEGFGYTIDVVLSNGILREGDRVVLCGLNGPIATNIRALLTPPPSRELRIKSEYVHHKEVKAALGVKIAANDLEKAVAGSRLLVVGEDDDEDELMDEVMDDLTGLLDSVDTSGKGVVVQASTLGSLEALLDFLKDMKIPVMSIGLGPVYKRDVMKASTMLERAPELAVMLCFDVKVDKEAEQYADEQNIKIFNADIIYHLFDSFTAYQAKLLEARRKEFMEYAVFPCVLKTIQIINKRNPMIIGVDVVEGAVRVGTPICAVRTDPTTKQPNIMVLGKVVSLEVNHKPLESVKKGQTAAGVAMRLDNPSSAQPTWGRHVDETDNLYSLISRKSIDTLKDPAFRDSVSRDDWLLIKKLKPVFDIK
Protein: Protein-arginine rhamnosyltransferase (EC 2.4.1.-) (EF-P arginine rhamnosyltransferase) (Q88LS1)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Function: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.
Interaction partners:
- Elongation factor P
Sequence:
MKATWDIFCSVVDNYGDIGVTWRLARQLVAEHGLAVRLWVDDLNAFTPMCPGADATAAQQWQHGVDVRHWPAAWLPVAPADVVIGAFACQLPAAYVEAMRARPQPPLWLNLEYLSAEDWVEGCHGLPSPQPNGLRKVFFFPGFTDKTGGLLREGSLLARRDGFQQSAEARRAFLQGLGVDLVPGALLISLFAYENPQLGNWLDALATADQPCHLLVPQGRVVAGLSQWLGEGPLHVGDVRTRGALTVQVLPFVSQDDFDRLLWSCDFNAVRGEDSFVRAQWAGQPMLWHIYVQDENAHWEKLEAFLAHYRCGLSDDADAALLGLWRAWNMDFDMGQAWRAARQHWPELQQHARLWGARQAAQPDLATALVHFYRNSL
Protein: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (GMP-PDE beta) (EC 3.1.4.35) (P23439)
Organism: Bos taurus (Bovine)
Function: Necessary for the formation of a functional phosphodiesterase holoenzyme (By similarity). Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock (By similarity). May participate in processes of transmission and amplification of the visual signal (By similarity).
Subcellular location: Membrane {ECO:0000250|UniProtKB:P35913}; Lipid-anchor {ECO:0000250|UniProtKB:P35913}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P35913}.
Interaction partners:
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Cyclic nucleotide-gated channel beta-1
- Cyclic nucleotide-gated channel alpha-1
- Rhodopsin
- Peripherin-2
- Guanylyl cyclase-activating protein 2
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Sequence:
MSLSEGQVHRFLDQNPGFADQYFGRKLSPEDVANACEDGCPEGCTSFRELCQVEESAALFELVQDMQENVNMERVVFKILRRLCSILHADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVQDVMECPHFSSFADELTDYVTRNILATPIMNGKDVVAVIMAVNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQAYSGPRTPDGREILFYKVIDYILHGKEDIKVIPSPPADHWALASGLPTYVAESGFICNIMNAPADEMFNFQEGPLDDSGWIVKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDREEIQLILPTRERLGKEPADCEEDELGKILKEVLPGPAKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEDQKKETTAKKVGTEICNGGPAPRSSTCRIL
Protein: H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp-140-associated protein of 57 kDa homolog) (AtNAP57) (Nucleolar protein NAP57 homolog) (Q9LD90)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit 3-like protein
- Telomerase reverse transcriptase
- Nucleolar protein 56
- Putative H/ACA ribonucleoprotein complex subunit 1-like protein 1
- H/ACA ribonucleoprotein complex subunit 2-like protein
- H/ACA ribonucleoprotein complex subunit 1-like protein 2
- Putative rRNA 2'-O-methyltransferase fibrillarin 3
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- rRNA 2'-O-methyltransferase fibrillarin 2
- Probable nucleolar protein 5-2
Sequence:
MAEVDISHSKKKKQDKTENDAADTGDYMIKPQSFTPAIDTSQWPILLKNYDRLNVRTGHYTPISAGHSPLKRPLQEYIRYGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGNLIVCIDRATRLVKSQQGAGKEYVCVARLHSAVPDVAKVARALESLTGAVFQRPPLISAVKRQLRIRTIYESKLLEYDADRHLVVFWVSCEAGTYIRTMCVHLGLLLGVGGHMQELRRVRSGILGENNNMVTMHDVMDAQFVYDNSRDESYLRRVIMPLEMILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDIDVGTEVVLMTTKGEAIAVGIAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNEKTPVEWSRNVVLPTGGDAIIAGAAAAPEEIKADAENGEAGEARKRKHDDSSDSPAPVTTKKSKTKEVEGEEAEEKVKSSKKKKKKDKEEEKEEEAGSEKKEKKKKKDKKEEVIEEVASPKSEKKKKKKSKDTEAAVDAEDESAAEKSEKKKKKKDKKKKNKDSEDDEE
Protein: Spliceosome-associated protein CWC15 homolog (O45766)
Organism: Caenorhabditis elegans
Function: Component of a spliceosomal complex that is required for activating pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9P013}.
Interaction partners:
- Cell division cycle 5-like protein
- Pleiotropic regulator 1
- Pre-mRNA-processing factor 19
- Protein BUD31 homolog
- Uncharacterized protein T27F2.1
- Tr-type G domain-containing protein
- Beta-catenin-like protein 1 N-terminal domain-containing protein
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- Probable U2 small nuclear ribonucleoprotein A'
- Pre-mRNA-splicing factor 8 homolog
Sequence:
MTTAHRPTFHPARGGTARGEGDLSKLSNQYSSKDMPSHTKMKYRQTGQETEADLRKKDLRRELEDKERNAIREKRARDSASSSSSHSKRQRMDQIAAESAASVDADEAVDELNSSDDDDSDEDDTAALMAELEKIKKERAEEKAARDEEIKEKEEKQRMENILAGNPLLNDTPAGSSTSGGDFTVKRRWDDDVVFKNCAKGVEERKKEVTFINDAIRSEFHKKFMDKYIK
Protein: RE67757p (Q8SYC8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSGKYDLLSEQGLRLDGRRPHELRRIKCKLGVFEQPDGSAYMEQGNTKVLAAVYGPHQAKGNQTESVINCQYSQATFSTAERKNRPRGDRKSLEFKLYLQQALSAAIKSELYPRSQIDIYVEVLQDDGANYAVALNAATLALIDAGICLNEFIVACTASLSKSNIPLTDISQFEEVSGGPKLTVAALPTAEKIAFLEMSERFHIDHLGTVIETAMAGCREIRDILEAAVKEHLLHMGSASDFAKVG
Protein: Type 3 secretion system translocon protein SctB (T3SS translocon protein SctB) (42 kDa antigen) (Invasin IpaC) (Invasion plasmid antigen C) (P18012)
Organism: Shigella flexneri
Function: Forms a pore with IpaB, which is inserted into host cell membrane through the Mxi/Spa apparatus, during cell contact. This pore probably allows the translocation of IpaA. The C-terminus of IpaC could be involved in actin polymerization that leads to the cell extension formation and its N-terminus could be involved in the conversion of filopodial extensions into lamellipodial extension. Most extensions results from Cdc42 activation by IpaC whereas the lamellipodial extensions result from the Rac activation by Cdc42.
Subcellular location: Secreted {ECO:0000269|PubMed:10545510, ECO:0000269|PubMed:7954817, ECO:0000269|PubMed:9001387}. Host membrane {ECO:0000269|PubMed:10545510, ECO:0000305|PubMed:9001387}; Single-pass membrane protein {ECO:0000255}. Note=Secreted via the type III secretion system (T3SS) (PubMed:10545510). Localizes at needle tips (PubMed:17367391, PubMed:19433542). IpaB/SctE and IpaC/SctB form a multimeric integral membrane complex in eukaryotic cell membranes (PubMed:17367391). {ECO:0000269|PubMed:10545510, ECO:0000269|PubMed:17367391, ECO:0000269|PubMed:19433542}.
Interaction partners:
Sequence:
MEIQNTKPTQTLYTDISTKQTQSSSETQKSQNYQQIAAHIPLNVGKNPVLTTTLNDDQLLKLSEQVQHDSEIIARLTDKKMKDLSEMSHTLTPENTLDISSLSSNAVSLIISVAVLLSALRTAETKLGSQLSLIAFDATKSAAENIVRQGLAALSSSITGAVTQVGITGIGAKKTHSGISDQKGALRKNLATAQSLEKELAGSKLGLNKQIDTNITSPQTNSSTKFLGKNKLAPDNISLSTEHKTSLSSPDISLQDKIDTQRRTYELNTLSAQQKQNIGRATMETSAVAGNISTSGGRYASALEEEEQLISQASSKQAEEASQVSKEASQATNQLIQKLLNIIDSINQSKNSAASQIAGNIRA
Protein: Protein kintoun (Dynein assembly factor 2, axonemal homolog) (Paralyzed flagella protein 13) (B5BUZ8)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03069, ECO:0000269|PubMed:19052621}. Note=Localizes exclusively in the cytoplasm but not in flagella. {ECO:0000269|PubMed:19052621}.
Interaction partners:
Sequence:
MPGKEENDTLEKSLKELNLTSDEMTKFEKAFKDPEFIKLFEEYAKEVSDPKVKAETDAYLRQIEQQGRAEDVYGAGTQLIVPDPAGAVIKTKVVSSSASKKQQQEQEKQEKEQQQQAAGAGKPEGPGKQGALPVGQKVFINICTCDKLERYSLTDAQDPATGRLRPKLTIPLSLGPVRQGADKQGAPAAVYDFVVHPDSWTFAAGNAAGLATLADTALDHVEQVGRCRLVRAWKRLNCRYKGTEGAAEPPVQCIRTSAAAAAGAAGEGAGGRVRPRPDVPGVPDLPGAKTAPPAAAGAAATAAAAAGAAEGGAGSSSRSTFSFDKSRKAGGTEAAGAVAKQEATITDPARPGYRHPDGAVTPEWGLLHRGEADLGEAWGDAGKGLAAGGRVPKELVVRVTLPDVSSAAPVDLDVGARCLALTVPNRYRLSVQLPYGVDDAKGRAKFDKARKVLEVTLPVVPPPAPPPGAAAAARAGLALIQELGGSEEAAEVKAEVEVEVADVMGRDQEAAHAKSEAGAGAGVKSPHTAAAASSGAAPAPAAASEEEEEEDKEDGGPAAGSGGDPAAAAAAAGASSGRELTENERKWRELHARQQQEEQEQQEAAEAAAAAAAAAAEPSSRSQLTGTVAQGGAAAAAESVAAAKQQVQQQPVAAAAAPTAVLRPRLNRELAMELD
Protein: MYB proto-oncogene, transcription factor (A0A8I5ZY95)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MCVHSYFCSIYSSDEDDEDIEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEDEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPSKASQTPVVSSFQKNNHLMGFAHASPPPTSQSSVNGEYPYYHIAEAQNISSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTCSYPGWHSTSIVDQTRPHGDSAPVSCLGENHATPSLPADPGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSDSSRCDLSSFEFSEEAAAFSPSQQHTGKTFQLQEREGHGTRSAGEPSLRVTRRVLSEASLRQAKASPLVFLRKRRGQASPTAAGDSSSSLFADVSSSTPKRSPVKSLPFSPSQFLNTSSNHENSGLDTPTLPSTPLIGHKLTPCHRDQTVKTQKENSIFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHVVEDLQDVIKQESDESGIVAEFHENGPPLLKKIKQEVDSPTEKAGNFFCSNHWEETNLSTQLFAQASPVADAPNILTSSVLMTPVSEDEDNVLKAFTVPKNRPLVGPLQPCVGAWEPTPSCGKTEDQMTASGQARKYVNTFSARTLVM
Protein: Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (F1RCT9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MYKMDYSYLNTYDSCMAAMEASAYADFNSCSQSNGFQYNPIRSGFSSGPACAPLATASCTLGALREHQPAPYSTVPYKFFSDASGLNEKRKQRRIRTTFTSSQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAANSKASSSSGGKKPSDARSSSEDDESKESTCSPTPDSTANMSSPGARSSLSPSPAPGPASTFSPASISPALKSSPWPSLGSGTPGPTHTHTQELLKAWQPADSMSGPFAGVLSSFHRKNNTIKSNLF
Protein: Kinesin-associated protein 3 (KAP-3) (KAP3) (P70188)
Organism: Mus musculus (Mouse)
Function: Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex.
Interaction partners:
- Kinesin-like protein KIF3A
- Kinesin-like protein KIF3B
- Kinesin-like protein KIF3C
- Kinesin-like protein KIF17
- Kinesin-like protein KIFC3
- Kinesin heavy chain isoform 5A
- Kinesin heavy chain isoform 5C
- 14-3-3 protein epsilon
- Intraflagellar transport protein 88 homolog
- Kinesin-like protein KIF2A
Sequence:
MQGEDARYLKRKVKGGNIDVHPSEKALIVQYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLSEVEQLLYYLQNRRDSLPGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSHFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDLENQTLRKDYDKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNENYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKLKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISSDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPFLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQLDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLITSEGAISPDFFNDFHLQNGDVVGQHAFPGSLGMDGFGQPLGILGRPATAYGFRPDEPYYYSFGSR
Protein: Transcription factor MYB117 (MYB-domain transcription factor LOF1) (Myb-related protein 117) (AtMYB117) (Protein CONSTRICTED FRUIT) (Protein LATERAL ORGAN FUSION 1) (Q9LQX5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that involved in boundary specification, meristem initiation and maintenance, and organ patterning. Functions in both lateral organ separation and axillary meristem formation, in part through genetic interaction with the NAC domain genes CUC2 and CUC3 and the homeobox gene STM. May be recruited by a variety of developmental programs for the development of floral organs and the initiation of ovule outgrowth.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
- Signaling peptide TAXIMIN 1
- Protein CUP-SHAPED COTYLEDON 3
- Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 3
- Protein CUP-SHAPED COTYLEDON 2
- Protein CUP-SHAPED COTYLEDON 1
- Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 4
Sequence:
MFITEKQVWMDEIVARRASSSWDFPFNDINIHQHHHRHCNTSHEFEILKSPLGDVAVHEEESNNNNPNFSNSESGKKETTDSGQSWSSSSSKPSVLGRGHWRPAEDVKLKELVSIYGPQNWNLIAEKLQGRSGKSCRLRWFNQLDPRINRRAFTEEEEERLMQAHRLYGNKWAMIARLFPGRTDNSVKNHWHVVMARKYREHSSAYRRRKLMSNNPLKPHLTNNHHPNPNPNYHSFISTNHYFAQPFPEFNLTHHLVNNAPITSDHNQLVLPFHCFQGYENNEPPMVVSMFGNQMMVGDNVGATSDALCNIPHIDPSNQEKPEPNDAMHWIGMDAVDEEVFEKAKQQPHFFDFLGLGTA
Protein: Rho guanine nucleotide exchange factor 26 (H2KYM3)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MLTYSKSWRSIRSRTGSLYTRARNRLTSSFRGGTKPDKLTVDGMEFDDSAQSSEVWIVTADFDGQVEGHLTVHKGDRVEIVEDQATDCAEYVQVVLCDQPTKHGLVPASIIAPPESGSVPDRPDDSNASGSTVSKRKSLRRIFANSSKERAAAANSSSSNNNSPATRQSTSTSSPVTANGHTTESSTSAPIGVLSSGEPTSSNSIPSSSTPTHTVPSSVPATVIPIVVAEDEKAEDCLPPPMENITINNSIDEKDMNEDSVAASDAVEPEVALPAKVEKTPEETARFKRSYVLMELVETEQDYVKDLTSVVEGYIGNLNKMDLPADLVGKDKIIFANIVNILEFHKTNFLKEIEKCSENYEAAGAAFVKYERRLHTLYVTYCQNKPKSDYLLAQDDFEAFFADTKAKLGHKVALCDLLIKPVQRIMKYQLLLKDILKFTERAKDKTDTLKKALQVMHVVPKACDDMMQVGRLQNFDKSLSAQGKLIHQGTLQISESIAGNVQKPKDRRIFLFEQSAIIADHIPPKKEFGNPTYIFKSQFMVNKMVFEPNVPDDPLRFVIKSSDPTQPTSFIANAQSQEEKDEWNRKMSELLDQQKRLLAALVDPRRYNDMSSGMGDLSLGAPGGDRRGAPSSANRSAASSSKKPAESPKKEGKSKSSLFSFGKKPAKSPTSPPPLDAAAAGKFQKVADDQVNLETDEKVKVLDVKNGYASVKKADGTVGKCPSYFLTMSDIPGTNFAEQIQYRREWQRRVDETDVEYGPSAFDTATSSTDNFDVLLELTTCERPVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQTNQLNSRLLIKHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEVRLKWKAESGLKYCIEYRILDDSSPENWLIASTNIEKTHVSLRNFARNSYSFRVFAYNQRVRSAPSQCICICFDGTEM
Protein: Non-specific serine/threonine protein kinase (D1MN51)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MPVGNSGSRSGRLARISQSNIRPFGSNGGGATNSYGPGTHPMSGAEPCSPTKKEKHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVRIRREIRIMSALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAYFEPETPSTASMLIRNMLRVNPERRATIFDIASHWWLNLEENMPVIQELPENQIIDHTPLTEREETMIVQDLADEQDVFMEFGHLSSETRRKIEDFRIRRKEAEEFNDNSPVKPPKARKTDELTGKISKEQPEEMKSAEKSLRGVKEEKEKPKVVDPNDPLERLRQIENRLGQNKKDKEAAKTSARVETVKLKEVKKEKSPEQQPEDPKTARGTSKPADSRAPSFVPVKDRPETSEPERPRTRPHLTASAYRIETDSLNMLMNQVLEQMEKGPVNLNIIARIKAHPLYDTRPMVKELLESIIAAQPEPVQKQTSKVVEQQTFSRQNTLTRKKKEDPLEEEIPEVPSPSRKMKERPWHSVEVGFDPDEEPEHDRMQESIASNATEVTVQDTSFEDDSSDEEERKKTPVASTPKTPVLIVEKQESSTNAEDEESDEGDDYSDAEMEELADEVDKKGPSDSKLAPVVENLEANPPPDPSSSPQFLDAFDRGLIKRQSKGKYQHTLINNYGRGVSTECESPTQQRKFFGGPQPSAELSPFLFDKAKEILQTYPNNKLDARGIDVELRRKLRMEKVKADLLKQPKDGDKPRNSYVGSVPPRSPPPIVVKSDGEELDDEEEEEEDEEEIEETDSEEGSDFENFKPKRPIIAAVRRDDGAVVPVIHQTTRPAVVSPNSQNPRYQVASPKTSTVIQATPEKVPVAGTSAKYLVTVAELKLKPTDKKEEAQLKEQLKDSEINSERKTSQTNLLFRPSAYRESDLYRRINAVTKGAAPSTISQDSDGKDTFESASAYIRRKNRERRQRNRTIGTAEEALRALERPSVDPYDDRAFSPLSTDPFYSHHSSGSAAPSALGYVRPRYHDDSYRTHRDSDYRPMSPTSRYTAAVTRDDRGKSTSYDPHETTRPSYDRGYITSSNASPSYTRKFEHEQPTLNSWANDRKFEVYKTRAERDAERNTYHPTGTTGASSYRPSSYYTSASDRPVTGLRRPEESYTSSTNYGRYDGRSTTPSNDQYAISTALAENQASSMNNRFRPTARRVASAMTDADRRNYHRSRSMDRNKVDYEYGSNLLNRLTTPDSHGDYSYVNYHDSSNGRSNITLEKDGQPRSILKNKQSADIEPRVESSYEPSNGVRSVFERLRRHLSLEKSVSPQRQNTSFYGRQLRVASVGPHSRNIDSTSSALDNPKKKRSLLSFNRRKTSEVRMGADGKLVTNGYDSTPSSRDFKRPSSPIDRIKSLFRKNESSGTGHSDYYNSSRNYTSSNPVSTTREPYVAQYRKYPGSTSRDTSSALNRYSYTPGLTDQRRHWYDDPNIY
Protein: MYB proto-oncogene, transcription factor (E9PLN0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MARRPRHSIYSSDEDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQVLPTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSFLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQESDESGIVAEFQENGPPLLKKIKQEVESPTDKSGNFFCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVLKAFTVPKNRSLASPLQVITIPTLVF