wanglab/gogpt-training-data huggingface dataset:
Protein: GDSL lipase (TcGLIP) (EC 3.1.1.-) (Pyrethrin type I synthase) (H6U1I8)
Organism: Tanacetum cinerariifolium (Dalmatian daisy) (Chrysanthemum cinerariifolium)
Function: Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide. Acyltransferase that catalyzes the esterification of terpene acids and lipid alcohol substrates into pyrethrins; mediates the transfer of a chrysanthemoyl moiety from the coenzyme A (CoA) thio-ester chrysanthemoyl CoA to pyrethrolone, and, to a lower extent, to jasmololone and cinerolone thus producing pyrethrins (e.g. pyrethrin type I). Can also use pyrethroyl CoA as substrate. Has also esterase activity, being able to cleave the ester bond of pyrethrin I, p-nitrophenyl butanoate and p-nitrophenyl octanoate to produce pyrethrolone and p-nitrophenol, respectively.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:22385412}.
Interaction partners:
Sequence:
MAVASRKLGALVLVAVLCLSLPTGCLSSQQAAALFIFGDSVFDPGNNNHINTHVNFKANFWPYGQSYFSSPTGRFSDGRIIPDFIAEYASLPIIPAYLEPNNDFTHGANFASAGAGALIASHAGLAVGLQTQLRYFGDLVDHYRQNLGDIKSRQLLSDAVYLFSCGGNDYQSPYYPYTQEQYVDIVIGNMTNVIKGIYEKGGRKFGVVNVPLIGCWPGMRAKQPGNTCNTEVDELTRLHNQAFAKRLEQLEKQLEGFVYAKFDLSTAILNRMKNPSKYGFKEGESACCGSGPFGGNYDCGRIKEFGLCDNATEYFFFDPFHPNELASRQFAEMFWDGDSMVTQPYNLKALFEGKPSTKYLPNDEL
Protein: Checkpoint protein rad17 (P50531)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Participates in checkpoint pathways arrest of the cell cycle. A mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
Subcellular location: Nucleus {ECO:0000269|PubMed:8846774}.
Interaction partners:
- DNA repair protein rad9
- Checkpoint protein hus1
- Replication factor C subunit 3
- DNA damage checkpoint control protein rad1
- Replication factor C subunit 2
- Replication factor C subunit 5
- Replication factor C subunit 4
- Protein kinase rad3
- S-M checkpoint control protein rad4
- Serine/threonine-protein kinase chk1
Sequence:
MRRQLSFHESTKRSLKKKKIRKIEKPSLVSKTSRDKNASITDIHEEDIEAFSDEENKIVHLNNLKEDRFQLWFEKYIPQKAADLAVHKSKISAIKQWMLTDSLESRLLLICGPSGCGKSTAVQVLAKELGYSLIEWLNPMNLKEPSNQESDTLSLTEKFSRFMSLCETYPELELMDSNNIQKRGKNAQGKKKFIFLDEIPHLSKFNGSLDAFRNVIRTALTSRGAFSIIMVLTEIQLNNLEGINSQDRNSFNSVQIMGNDLLQDPRVTVLQFNPIAPTYMKKCLGSILRKEGVPKSPKLLSLVENICSASEGDLRSAINSLQLSISQSFEKKGTKNIREVKEGKGKGNDFSLEAAQVLERLSKSDSEAYARFKNYKSAYIPKSDKNENSFFKKDVGLGMMHAIGKVVWNKREGDDEVLKASSQQTGNSERIKGVKVSKSQENKNCISLKSDQRERMLNVDQCFTSKRRSLVDIESTINQSGLSGSVFRYGLFENYVDSCVTTDEAFNVCDLLSISDCLSHDFPYSYTGDEISTWFSVQGTLFYLPSPVPRKWRQLRFQQWNNEGIVRGIFDDYMVIYGKRSVSDPVIEAHEDQVLEDIDDPIEDED
Protein: Protein ENTREP3 (Endosomal transmembrane epsin interactor 3) (Protein COTE1) (P81408)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL
Protein: Pantothenate kinase (EC 2.7.1.33) (Pantothenic acid kinase) (Rts protein) (P0A6I3)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Phosphopantetheine adenylyltransferase
- Coenzyme A biosynthesis bifunctional protein CoaBC
- Pantothenate synthetase
- Acyl carrier protein phosphodiesterase
- Dephospho-CoA kinase
- Nucleoside triphosphate pyrophosphohydrolase
Sequence:
MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
Protein: Gamma-crystallin B (Gamma-B-crystallin) (Gamma-crystallin 1-2) (P10066)
Organism: Rattus norvegicus (Rat)
Function: Crystallins are the dominant structural components of the vertebrate eye lens.
Interaction partners:
- Alpha-crystallin A chain
- Gamma-crystallin F
- Gamma-crystallin A.
- Alpha-crystallin B chain
Sequence:
MGKITFFEDRGFQGRCYECSSDCPNLQTYFSRCNSVRVDSGCWMLYERPNYQGHQYFLRRGDYPDYQQWMGFSDSIRSCRLIPQHSGTYRMRIYERDDFRGQMSEITDDCLSLQDRFHLSEIHSLNVMEGCWVLYEMPSYRGRQYLLRPGEYRRYLDWGAANAKVGSFRRVMDFY
Protein: Leucine-rich repeat protein soc-2 homolog (Protein Sur-8 homolog) (Protein soc-2 homolog) (Q9VEK6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).
Interaction partners:
- Diphthine methyltransferase
- Uncharacterized protein
Sequence:
MNLCSSGATASTTSLSSTGQAERSGGVPGGGAEGGGGSGNSGGGGKTSNGSAEAPTLCFAGGSGTAGAIAGTEELSNANSPANGAGGATGSTGSGQQPTGSNGHSHLHNENNANMPPETRPKMVTVKHPESNKPKPTTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPSTVKECVHLTELYLYSNKIGQLPPEIGCLVSLRNLALNENSLTSLPESLQNCSQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLSTIPPEIQAGGPSLVLQWLKMHSPYRQM
Protein: Mediator of RNA polymerase II transcription subunit 5 (Mediator complex subunit 5) (Negative regulator of URS2 protein 1) (P53114)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 2
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 13
- RNA polymerase II holoenzyme cyclin-like subunit
- Mediator of RNA polymerase II transcription subunit 15
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 12
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 9
Sequence:
MEKESVYNLALKCAERQLTSMEFSNLYKEFFNEKFPSLIQEEEEDTTTTANINEVKKASDLVDTPSNNTAATADTTHLHEALDIVCSDFVKILNLEKPLILADYIVEVLLVNYNSDMIKCFLPKLNSVRNSLLLAHFFSKSCSFFAKLSDTLIIDQVRKDLGNVIVPNILSLDMNSMNKELIAIVSKLLQTTLKLSPSPILLTSAGCKNGSFTLLNQLSQTNKLLFKRVSQTFEAKLHFKDTKPFLNKDSTNEFVGSPSLTSPQYIPSPLSSTKPPGSVNSAAKYKDMKLLRYYKNIWLNNKIINWEISNPDFLSKYSAITSSIFQESFNSVQNLDQLLTDLIETSFTCFAQFVSNKQYHQANSNLTLLERKWVIFITKHLPLLILENSSRSPRVVTNALDNIDEKVVKAIRIYFTEKDDNKTNNEDLFDDYPSTSLDIRHDFIKGLIMLNLQPASVINNYLREDQMIDTSILPTRDDLFVRNLQGIQEVVHNTNSFIISSLDTLELESITESITHDSSNGLFQVLHNFESVAPTKQREIVKAFLSIFEDAIKELNYNRIAKICALLFFNFSHSLTTILSFSSPAALMKTLIKFVDLSRNGRNGSNGNDESSEYETINISLSFSWAILLIINLTQTYGISVVDVALKYPELSIKNSFIINFISNLPNVSDKYYLEESNVNDSDMLTKSHNTVQSWLCDLFVNGSITDQLIQNIETRQLANLIPFIVKQVLLSVEIGVLTDISSLIGGFEYFLQPLLLVGLIKTFYWLEQFLSCVKNDTISEDILQGIFNLLNTLFNPVTLNEDSKAFHTAVLRLNAIPLLKVLRKFRVQSQSNYGIYSSDAQGDPNLEPLIAKLVAVLNVSPVYDVDPRIINSENDYSRKQLGYGKFLILNENPINKIMTNQINSFWSLHSSTYYNLDYLFELIELVTPKSFLFDVLKTLEYKLATYGVPGSENKRGSLDSEHVFDYFFYFLVLYDVKTAEEASQLIEYMENDAKKSKGDVDIKGEDLHEKNDSAEVRQETQPKAEATQDDDFDMLFGENDTSTQAYEEEEENEDNDGNNRTNNVPMIKAEETPSKTNKISILKRHSFAVLLHERKLLNDLALENGEITKTENEKFISYHDKYLCMLKTCVF
Protein: At3g09000 (MZB10.3 protein) (Proline-rich family protein) (T16O11.4 protein) (Q9S7V5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At3g53320
- TRIO/F-actin-binding protein
- Glucose-6-phosphate/phosphate translocator 1, chloroplastic
Sequence:
MLTHDRDEELSLFLEMRRREKEHRADSLLTGSDNVSINATLTAAAAAALSGVSETASSQRYPLRRTAAENFLYSENEKSDYDWLLTPPGTPQFEKESHRSVMNQHDAPNSRPTVLKSRLGNCREDIVSGNNNKPQTSSSSVAGLRRPSSSGSSRSTSRPATPTRRSTTPTTSTSRPVTTRASNSRSSTPTSRATLTAARATTSTAAPRTTTTSSGSARSATPTRSNPRPSSASSKKPVSRPATPTRRPSTPTGPSIVSSKAPSRGTSPSPTVNSLSKAPSRGTSPSPTLNSSRPWKPPEMPGFSLEAPPNLRTTLADRPVSASRGRPGVASAPGSRSGSIERGGGPTSGGSGNARRQSCSPSRGRAPIGNTNGSLTGVRGRAKASNGGSGCDNLSPVAMGNKMVERVVNMRKLGPPRLTENGGRGSGKSSSAFNSLGYGRNLSKSSIDMAIRHMDIRRGMTGNLRPLVTKVPASSMYSVRSRPGSVSSSPVATSSTVSSSDPSVDNINILCLDGNEAENDDLLSERSYAASPRNQYPKFTS
Protein: Protein unc-119 homolog A (Retinal protein 4) (mRG4) (Q9Z2R6)
Organism: Mus musculus (Mouse)
Function: Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q13432}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q13432}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q13432}. Note=ocalizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells. {ECO:0000250|UniProtKB:Q13432}.
Interaction partners:
- ADP-ribosylation factor-like protein 3
- ADP-ribosylation factor-like protein 2
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
- Peptidyl-prolyl cis-trans isomerase E
- Guanine nucleotide-binding protein G
- Nephrocystin-3
- Tumor necrosis factor receptor superfamily member EDAR
- ADP-ribosylation factor-like protein 13A
- Acetoacetyl-CoA synthetase
- Fasciculation and elongation protein zeta-1
Sequence:
MKVKKGGGGTGSGAEPVPGASNRSAEPTREPGAEAESGSESEPEPGPGPRLGPLQGKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPPVSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP
Protein: Serine/threonine protein phosphatase 2A regulatory subunit (Q9NFM7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDNEALDPTIKSSTSAATPTAAASETTTTAASSVVETTTTIAAATASAAESKNETTATNNNSNTSGSISSSSSNNIVIPASATNGIKESNSNLSTTTTAAAVAAATTVEGVAPAITSTIVVTGGTPPLSSLANKLKDNTPPYDAPPPTPISKVLNITGTPIVRKEKRQTSARYNASKNCELTALIPLNEKTAASEREELFIQKIQQCCTLFDFSEPLSDLKFKEVKRAALHEMVDFLTNQNGVITEVIYPEAINMFAVNLFRTLPPSSNPNGAEFDPEEDEPTLESSWPHLQLVYELFLRFLESPDFQPSMAKRFIDHQFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNVFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQLTYCVVQFLEKDPSLSEAVIKSLLKFWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIAKCVSSPHFQVAERALYYWNNEYIMSLITDNSAVILPIMFPALNRNSKTHWNKNIHGLIYNALKLFMEIDQRLFDECSKNYKQEKQMEREKLSQREELWQQVESLAKTNPEWTKARRFNDCLPVSDSRALCDQYSENSDSAYDQSEQRARQPPPPLPPQKQAHQEPREVRQALATLTTLNNY
Protein: Adenylyl cyclase-associated protein 1 (CAP 1) (P40124)
Organism: Mus musculus (Mouse)
Function: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Resistin
- Cofilin-1
- Resistin-like gamma
- Drebrin-like protein
- Profilin-1
- WD repeat-containing protein 1
- Profilin-4
- Drebrin
- Twinfilin-1
- Twinfilin-2
Sequence:
MADMQNLVERLERAVGRLEAVSHTSDMHCGYGDSPSKGAVPYVQAFDSLLANPVAEYLKMSKEIGGDVQKHAEMVHTGLKLERALLATASQCQQPAGNKLSDLLAPISEQIQEVITFREKNRGSKFFNHLSAVSESIQALGWVALAAKPGPFVKEMNDAAMFYTNRVLKEYRDVDKKHVDWVRAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSVGSGPPPPPPGPPPPPISTSSGSDDSASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKPATKKEPALLELEGKKWRVENQENVSNLVIDDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSRDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG
Protein: 2-Hydroxyacid oxidase 2 (HAOX2) (EC 1.1.3.15) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Medium chain alpha-hydroxy acid oxidase) (Medium-chain L-2-hydroxy acid oxidase) (Q9NYQ2)
Organism: Mus musculus (Mouse)
Function: Oxidase that catalyzes the oxidation of medium chain hydroxyacids such as 2-hydroxyoctanoate, to the correspondong 2-oxoacids. Its role in the oxidation of 2-hydroxy fatty acids may contribute to the general pathway of fatty acid alpha-oxidation. Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. Is not active on glycolate, glyoxylate, L-lactate, 2-hydroxybutanoate and 2-hydroxyhexadecanoate.
Subcellular location: Peroxisome {ECO:0000269|PubMed:10777549}.
Interaction partners:
- Alanine--glyoxylate aminotransferase
- Glyoxylate reductase/hydroxypyruvate reductase
- 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
- 2-Hydroxyacid oxidase 1
- Catalase
- Glycerol-3-phosphate phosphatase
- D-amino-acid oxidase
- Sulfotransferase
Sequence:
MSLLCLADFKAQAQKQLSKTSWDFIEGEADDGITYNDNLAAFRRIRLRPRYLRDVSKIDTRTTIQGQEINAPICISPTAFHSIAWADGEKSTAKAAQKANICYVISSYASYTVEDIVAAAPGGLHWFQLYVQPDWDINKQMVQRIEALGFKALVVTVDAPVLGNRRGNKRSLLDLEANIKLKDLRSPGESKSGLPTPLSMPSSSSCWNDLPLLQSMTRLPIILKGILTKEDAELAVKHNIRGIIVSNHGGRQLDEVPASIDALREVVAAVNGKIEVYMDGGVRTGNDVLKALALGARCIFLGRPIIWGLACKGEDGVKEVLDILKEELHTCMALSGCRSVAEISPDLIQFSRL
Protein: Dynactin subunit 5 (Q9NHE4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MEIPDTYYSKDEYVETASGNKVSRHTVLCGSQNIILNGKVIVQSGAIIRGDLANVRTGRYCVIGKNSVIRPPYKQFSKGIAFFPMHVGEHVFVGEGAVVSAATIGSYVYIGKNAIIGRRCVLKDCCAIEDGAVLPPETTVSSYMRYTARGTIEGGQGNPYFVPAAMQDEMINYTKSFYEHFVRAPAPAS
Protein: Uncharacterized protein (Q3TMS8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MVLTALNVAHFQSWVGGLRGEAMLPHPHPHLLPKVVVKTVLVSPTPFPPRDGAHVRQACSCAPQLTKVLQSRIAETKASKSQAWNKTPSEHCTHRPHAILAAAAPAAIASTLLEC
Protein: PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein) (Q8WW12)
Organism: Homo sapiens (Human)
Function: May be involved in cell cycle regulation.
Subcellular location: Nucleus {ECO:0000269|PubMed:12176013}.
Interaction partners:
- E3 ubiquitin-protein ligase UHRF2
Sequence:
MADGKAGDEKPEKSQRAGAAGGPEEEAEKPVKTKTVSSSNGGESSSRSAEKRSAEEEAADLPTKPTKISKFGFAIGSQTTKKASAISIKLGSSKPKETVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNVHDQDN
Protein: EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2) (Q14657)
Organism: Homo sapiens (Human)
Function: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:28805828}. Nucleus {ECO:0000269|PubMed:22912744, ECO:0000269|PubMed:27903914, ECO:0000269|PubMed:28805828}.
Interaction partners:
- tRNA N6-adenosine threonylcarbamoyltransferase
- EKC/KEOPS complex subunit TP53RK
- EKC/KEOPS complex subunit GON7
- EKC/KEOPS complex subunit TPRKB
- Transmembrane protein 187
- tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial
- Threonylcarbamoyl-AMP synthase
- Nucleoporin Nup43
Sequence:
MRDADADAGGGADGGDGRGGHSCRGGVDTAAAPAGGAPPAHAPGPGRDAASAARGSRMRPHIFTLSVPFPTPLEAEIAHGSLAPDAEPHQRVVGKDLTVSGRILVVRWKAEDCRLLRISVINFLDQLSLVVRTMQRFGPPVSR
Protein: Transcription factor bHLH115 (Basic helix-loop-helix protein 115) (AtbHLH115) (bHLH 115) (Transcription factor EN 134) (bHLH transcription factor bHLH115) (Q9C682)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:25452667}.
Interaction partners:
- Transcription factor bHLH101
- Transcription factor ORG2
- Transcription factor ORG3
- Transcription factor bHLH100
- Zinc finger protein BRUTUS
- Ferric reduction oxidase 2
- Transcription factor bHLH47
- Fe
- Probable nicotianamine synthase 4
- Ferric reduction oxidase 3, mitochondrial
Sequence:
MVSPENTNWLSDYPLIEGAFSDQNPTFPWQIDGSATVSVEVDGFLCDADVIKEPSSRKRIKTESCTGSNSKACREKQRRDRLNDKFTELSSVLEPGRTPKTDKVAIINDAIRMVNQARDEAQKLKDLNSSLQEKIKELKDEKNELRDEKQKLKVEKERIDQQLKAIKTQPQPQPCFLPNPQTLSQAQAPGSKLVPFTTYPGFAMWQFMPPAAVDTSQDHVLRPPVA
Protein: Nuclear pore complex interacting protein family member A3 (E9PNV8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVKLSIVLTPRFLSHDQGQLTKELQQHVKSVTCPCEYLRKVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAKICKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAAEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPPECLLTPLPPSALPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPKCVCSLPFHPQRMIISRN
Protein: Small ribosomal subunit protein bS16c (30S ribosomal protein S16, chloroplastic) (P12151)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Os01g0220300 protein
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS2c
- Os02g0102400 protein
- Os07g0658200 protein
- Small ribosomal subunit protein uS9c
- Large ribosomal subunit protein bL27c
- Large ribosomal subunit protein bL33c
- 40S ribosomal protein S29, putative, expressed
- 50S ribosomal protein L31
Sequence:
MLKLRLKRCGRKQRAVYRIVAIDVRSRREGRDLRKVGFYDPIKNQTCLNVPAILYFLEKGAQPTRTVSDILRKAEFFKEKERTLS
Protein: cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier (B4DLN1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLPAAARPLWGPCLGLRAAAFRLARRQVPCVCAVRHMRSSGHQRCEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLVPMGGVMSGAVPAAAAQEAVEEDIPIAKERTHFTVRLTEAKPVDKVKLIKEIKNYIQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEATQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRKNFGIKVPS
Protein: Protein fork head (P14734)
Organism: Drosophila melanogaster (Fruit fly)
Function: Fkh promotes terminal as opposed to segmental development. In the absence of fkh, this developmental switch does not occur. The nuclear localization of the fkh protein suggest that fkh regulates the transcription of other, subordinate, genes.
Subcellular location: Nucleus.
Interaction partners:
- Ribosomal protein S6 kinase
- Grain, isoform C
- GATAe, isoform A
- GATA-binding factor A
- Homeobox protein extradenticle
- Protein tailless
Sequence:
MQKLYAEPPPSSAPVSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEAGGASIAGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITDYHSSMHPLKQEPSGYTPSSHPFSINRLLPTESKADIKMYDMSQYAGYNALSPLTNSHAALGQDSYYQSLGYHAPAGTTSL
Protein: Tubulin alpha chain (A9PL16)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPSDKTVGGGDDAFNTFFSETGAGKHVPRAIFVDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFSAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVSVLLDNEAIYDICRRSLDIERPTYTNLNRLVSQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVISAAKAYHEQLSVAEITNTAFEPSSMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAEVQRAVCMISNSTSVAEVVSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGADSAEGDEEDEGDEY
Protein: MIF4G domain-containing protein (Q57VB4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable eukaryotic initiation factor 4A
- Eukaryotic translation initiation factor 4E type 6
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- carnosine N-methyltransferase
- Uncharacterized protein
Sequence:
MNCSAPGLYSLVTNEVWKPSVFRPPTLQKRSRPVAKTTLTPMAQPWYPSNANGGCDSTSSGPQSCQKDGPRLLPPPALGQSPTFGSDIEKEFPTVLCSSSVVAPTATCATRRASAFTKAAMEARTYPLDMFMSVSKDAAHTPYGVLCWAVKQYVTCSYLKVPTHLQLSLRDFGGRPAEVDARGLMGTCLKVKSRAKPVRLTHHKVLSILSRLTEAKYDTLLSELKLLPLRQVEDDELSEICKIVFEKAVSEPSYTSLYARLAQDVCKEKKEERDSSVWNEGFQRRFRRTLVKLCEVQFHQPLQLSGDDVVDRTTGTPLDEEEVEMKRSRLKHRLVGNIRFVAELFKVGVLSGRVVTEIVQILVSDYNPDAPTAKEEHVFELFTTLLRLTAAQLKDCEVNLLIRSLGIAKTIELSHPKPRVRFLMMDLGDLNRKNGWVEQEQIQSHVKEPKQLKKVPGPAPAAPASPTTSTPTAKRAEKLGSRLRDMSSRCCADAEVSLRKENGNGTQTPGSTSYGNKVADGCADGGNNKNNNGGVSNAVKTNSNGKHTSRTGIENRSGSDETAKVKPSNGAAVPSSAKQSTNASRRVSHNPYCKLSPANILDLKNGDAKAASGNSNIPYTESPLSPAASSTDLSLSSSSSGHFHNNQGNGGTAMHSGLCSPFLERDKMVNERKMNIEKITMQLMALFRTGDEETTATILHTMGLKNMVMCLTWWLRLATTASGNSDNAQCYGDYSKVAALLSALLSIRNDAYATSTVFSTVLEWLRFDMEKHEYESFPGMFEKIAQMIRQCHLPITDSLPNVEVVREIMHGGMFNVLLRELIINGGITAPVSDLVKSCHPASAEIICHLHDPADDSQMLFVAAQNRFHFLSYLLCVSSMTRIDAQSGFHLRTPLLPPRCNNSQAEWTPLVECLALPSVASDPESLLFVKMWDHATNGDAASLWRDEAIRLALETPAGQNSTTSSLISVMRVVGVLLMGLVTKCMTVGACGTNNGSSGGNASGAHALAETADVHYVVSGILKQHPAPLYQAATVVELVMHHTRALSGTSECPTFDNARLKALKNEFDDWCEAGLVDRPAVLELLRVVDATKDNFNLYPAYHNCVADVPWHVAIRSLGGN
Protein: Gibberellin-regulated protein 4 (GAST1 protein homolog 4) (P46690)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Gibberellin-regulated protein involved in the regulation of floral meristem and floral organ identity, and promotion of seed size and weight. May play a role in the promotion of gibberellin responses such as regulation of flowering under short-day conditions, seed germination and inhibition of gibberellin oxidase. Possesses redox activity in E.coli and may function in redox regulation in planta.
Subcellular location: Secreted.
Interaction partners:
- Defensin-like protein 178
- Defensin-like protein 176
- Defensin-like protein 98
Sequence:
MAKSYGAIFLLTLIVLFMLQTMVMASSGSNVKWSQKRYGPGSLKRTQCPSECDRRCKKTQYHKACITFCNKCCRKCLCVPPGYYGNKQVCSCYNNWKTQEGGPKCP