wanglab/gogpt-training-data huggingface dataset:
Protein: Phosphate-binding protein PstS (PBP) (P0AG82)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex PstSACB involved in phosphate import.
Subcellular location: Periplasm.
Interaction partners:
- Phosphate transport system permease protein PstA
- Phosphate import ATP-binding protein PstB
- Phosphate transport system permease protein PstC
- Phosphate-specific transport system accessory protein PhoU
- Phosphate regulon sensor protein PhoR
- Phosphate regulon transcriptional regulatory protein PhoB
- Alkaline phosphatase
- Low-affinity inorganic phosphate transporter PitB
- Phosphonates-binding periplasmic protein
- sn-glycerol-3-phosphate-binding periplasmic protein UgpB
Sequence:
MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKWADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIGGVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRRADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGYVEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWPITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWKTNIKDSSGKPLY
Protein: Ribonucleoprotein 1 (P32385)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Nuclear GTP-binding protein NUG1
Sequence:
MLIEEIEFYNVNGKKTTTVVPENTKIKKRVLNDRRTLYVGNLPKNCRKQDLRDLFEPNYGKITINMLKKKPLKKPLKRFAFIEFQEGVNLKKVKEKMNGKIFMNEKIVIENILTKEEKSFEKNQKSNKKTAPDLKPLSTNTLYVKNIPMKSTNEDLAKIFGVDPKNINFVRRELVDLRTNKVFFSDEFHTGEAFIKFDNLGTGDSIQKKCREFKGRKASNGRVLLVKIASAKKNEQKQEGGDNTKIKQN
Protein: Probable exo-1,4-beta-xylosidase xlnD (EC 3.2.1.37) (1,4-beta-D-xylan xylohydrolase xlnD) (Beta-xylosidase A) (Beta-xylosidase xlnD) (Xylobiase xlnD) (A2QA27)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Function: Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MAHSMSRPVAATAAALLALALPQALAQANTSYVDYNIEANPDLYPLCIETIPLSFPDCQNGPLRSHLICDETATPYDRAASLISLFTLDELIANTGNTGLGVSRLGLPAYQVWSEALHGLDRANFSDSGAYNWATSFPQPILTTAALNRTLIHQIASIISTQGRAFNNAGRYGLDVYAPNINTFRHPVWGRGQETPGEDVSLAAVYAYEYITGIQGPDPESNLKLAATAKHYAGYDIENWHNHSRLGNDMNITQQDLSEYYTPQFHVAARDAKVQSVMCAYNAVNGVPACADSYFLQTLLRDTFGFVDHGYVSSDCDAAYNIYNPHGYASSQAAAAAEAILAGTDIDCGTTYQWHLNESIAAGDLSRDDIEQGVIRLYTTLVQAGYFDSNTTKANNPYRDLSWSDVLETDAWNISYQAATQGIVLLKNSNNVLPLTEKAYPPSNTTVALIGPWANATTQLLGNYYGNAPYMISPRAAFEEAGYKVNFAEGTGISSTSTSGFAAALSAAQSADVIIYAGGIDNTLEAEALDRESIAWPGNQLDLIQKLASAAGKKPLIVLQMGGGQVDSSSLKNNTNVSALLWGGYPGQSGGFALRDIITGKKNPAGRLVTTQYPASYAEEFPATDMNLRPEGDNPGQTYKWYTGEAVYEFGHGLFYTTFAESSSNTTTKEVKLNIQDILSQTHEDLASITQLPVLNFTANIRNTGKLESDYTAMVFANTSDAGPAPYPKKWLVGWDRLGEVKVGETRELRVPVEVGSFARVNEDGDWVVFPGTFELALNLERKVRVKVVLEGEEEVVLKWPGKE
Protein: Probable clathrin assembly protein At4g32285 (Q8S9J8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane, clathrin-coated pit {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. Note=Colocalized with clathrin in the Golgi area. {ECO:0000250}.
Interaction partners:
- AP-2 complex subunit alpha-2
- AP-5 complex subunit mu
- Clathrin interactor EPSIN 2
- Coatomer subunit alpha-2
- Coatomer subunit alpha-1
- Beta-adaptin-like protein B
- Clathrin heavy chain 1
- Putative clathrin assembly protein At5g65370
- Coatomer subunit beta'-1
- Clathrin heavy chain 2
Sequence:
MALSMRKAIGVVKDQTSIGIAKVASNMAPDLEVAIVKATSHDDDQSSDKYIREILSLTSLSRGYVHACVTSVSRRLKKTRDWIVALKALMLVHRLLNEGDPLFQEEILYATRRGTRILNMSDFRDEAHSSSWDHSAFVRTYASYLDQRLELALFERRGRNGGGSSSSHQSNGDDGYNRSRDDFRSPPPRTYDYETGNGFGMPKRSRSFGDVNEIGAREEKKSVTPLREMTPERIFGKMGHLQRLLDRFLSCRPTGLAKNSRMILIAMYPVVKESFRLYADICEVLAVLLDKFFDMEYTDCVKAFDAYASAAKQIDELIAFYHWCKDTGVARSSEYPEVQRITSKLLETLEEFVRDRAKRAKSPERKEIEAPPAPAPPVEEPVDMNEIKALPPPENHTPPPPPAPEPKPQQPQVTDDLVNLREDDVSGDDQGNKFALALFAGPPANNGKWEAFSSDNNVTSAWQNPAAELGKADWELALVETASNLEHQKAAMGGGLDPLLLNGMYDQGAVRQHVSTSELTGGSSSSVALPLPGKVNSHILALPAPDGTVQKVNQDPFAASLTIPPPSYVQMAEMDKKQYLLTQEQQLWQQYQQEGMRGQASLAKMNTAQTAMPYGMPPVNGMGPSPMGYYYNNPY
Protein: Probable CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) (CDP-diacylglycerol phosphatidylhydrolase) (CDP-diglyceride hydrolase) (P9WPG9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein Rv2288
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- Phosphatidate cytidylyltransferase
- Diacylglycerol kinase
- Putative cardiolipin synthase
- 1-acylglycerol-3-phosphate O-acyltransferase
- Phosphatidylinositol phosphate synthase
- Probable phosphatidylglycerophosphate synthase
- Uncharacterized Na
Sequence:
MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKADFDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTSAALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGTEDQPVAAETLQDHDCSITKS
Protein: Inner centromere protein SLI15 (INCENP-related protein SLI15) (P38283)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for high-fidelity chromosome segregation during the later part of each cell cycle in association with the protein kinase IPL1. Stimulates IPL1 kinase activity and facilitates its association with the mitotic spindle. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles.
Subcellular location: Nucleus {ECO:0000269|PubMed:10385519}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:10385519, ECO:0000269|PubMed:11724818}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:11724818}. Note=Associates with the mitotic spindle and the kinetochore (PubMed:11724818). {ECO:0000269|PubMed:11724818}.
Interaction partners:
- Chromosomal passenger complex protein BIR1
- N-terminal-borealin-like protein
- Aurora kinase
- Tyrosine-protein phosphatase CDC14
- Protein BIM1
- Inner kinetochore subunit CTF19
- Centromere DNA-binding protein complex CBF3 subunit A
- Inner kinetochore subunit OKP1
- Inner kinetochore subunit MCM21
- Spindle assembly checkpoint serine/threonine-protein kinase BUB1
Sequence:
MDWAIKAARKKTQRKPGSTRSIIETLDDLNNLTTDAHSEINQRLYESSEWLRNNVYMNTLKYEDKKMEESLISPENTHNKMDVEFPKMKGEYELSNSQNDAAKDVTKTPRNGLHNDKSITPKSLRRKEVTEGMNRFSIHDTNKSPVEPLNSVKVDANESEKSSPWSPYKVEKVLRESSKTSESPINTKRFDNQTWAAKEEMENEPILQALKKAESVKVKPPPNSGIARSQRRSNMFVPLPNKDPLIIQHIPPTKSSGSIPKVRTVKESPIAFKKKSTINSPAIRAVENSDTAGSTKASSVFDRLSSIPTKSFENKISRGNVGHKYSSSSIDLTGSPMKKVSQKFKSINSTDTDMQEALRDIFSVKNKITKNNSPKGKNSRKSSIPRFDKTSLKLTTHKKLAIIAEQKKKSKHSSDVHKTGSRPHSISPTKISVDSSSPSKEVKNYYQSPVRGYLRPTKASISPNKNKNLTTSQTPHRLKIKEKTLRKLSPNIADISKPESRKSKNYRLTNLQLLPPAEAERDDLKKKFDKRLSGIMRSQQEHHRRKQEKQKRMSHLEQDLKKQTSFSNDYKDIRLKESLAPFDNHVRDTINKNTAFSTDNILATINTVDHREIIGNVTPKIASVNDSLPEINTDSEDEASVTLAAWAKSPYLQEQLIRQQDINPQTIFGPIPPLHTDEIFPNPRLNRLKPRQIVPKRS
Protein: Sad1-interacting factor 1 (O74843)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000269|PubMed:14655046}; Multi-pass membrane protein {ECO:0000269|PubMed:14655046}.
Interaction partners:
- Protein transport protein sec13
- Protein transport protein sec24
- Syntaxin ufe1
- COPII coat assembly protein sec16
- AP-2 complex subunit mu
- Glutathione S-transferase 3
- Acetyl-CoA carboxylase
- Dynein light chain Tctex-type
- ATPase get3
- Protein get1
Sequence:
MSTASEQARLRRERRLNKIKQGGASRINQILGQNSDDSQSDVRATASEEAVHSETATPVTPMSSGFMEKRDDTFNADQVEYLPSQDYHNLESSPFKLQCDSPYNVPPENMFNQNPDFANFFQAMLQSAKEGSDTNFQGENEQIPQATAPLKNLVEKYAHLLAISIVVIVCYFKHLPLLPWTFTVEACLFSIQFVLDRNNGPSYSLLASLASQLPPPYGAMIRHTTSYVPYFTQLITDACMTIFALGLCCYFYPSLVY
Protein: pre-mRNA 3' end processing protein pfs-2 (Polyadenylation factor subunit homolog 2) (U4PCM1)
Organism: Caenorhabditis elegans
Function: Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:20530551}. Note=Also localizes to a small subnuclear ring in neurons. In neurons, partially co-localizes with sydn-1 in the nucleus. {ECO:0000269|PubMed:20530551}.
Interaction partners:
- Cleavage and polyadenylation specificity factor subunit 4
- Pre-mRNA polyadenylation factor Fip1 domain-containing protein
- DUF3453 domain-containing protein
- RNA polymerase II subunit A C-terminal domain phosphatase ssup-72
- Probable cleavage and polyadenylation specificity factor subunit 1
- Cleavage and polyadenylation specificity factor subunit 3
- Probable cleavage and polyadenylation specificity factor subunit 2
- Suppressor of forked domain-containing protein
- E3 ubiquitin-protein ligase RBBP6
- WD_REPEATS_REGION domain-containing protein
Sequence:
MNGGMMRGNQMPNVTLTIQPSTSSMQNSQPRIMNNHHHPHNRFQREHVMPDVMGDGPGRRLRKNVANVRRHVDYVSTVLNHCENRLWQYGKQRILQQPDILYQQYAVPADSTPDVPVDCILTKFIRTAMNKVKCPVYSVCWSPEGKRLITGCQTGEFTLWNGTAFNFETILQAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAHMFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYTEERVLRGHGAEVRCIDWHPTKGLIATGSRDTQQPVKIWDPKSGSCLATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYRAHKKEVISLAWHPIHEGLFVSGGGDGSIVYWMVDGEKEIGLLEHAHDQAIWSMKWHPLGHILATGSNDNNTKFWARNRPGDTVEDIFGLSNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGMGLDEHLYEQLNRDHNMMTTDSTLLVPDDLTRQNFAPMIGAKRTLIKQPPAKKAQRQFERMWNNSKGIGAGSDDFTTMKGGLGREDAEGAQFGPSKSFLGPPTTGGSLLGPSQPRPQEFRSVPPPQQQQGPPPNWRHQGPPMSGPGQGYGPPGRMGGNQGGWQRPPPQGSYGGQGPPQGSYGGQGTLQGSYASQQGPPPRQIQHIPSDIDYRTAPSSSNGSTGDVDMRTMVPNQPPSGEPEHWRGPPPVSHQQQSQQQHPPPINMQRMDPRRDPRMLSGRSDQLSPSGPPPQQQQSSAQQGGKNQWMPQFEAGQNQNQGNYAGNRGGGVGGRGRGRGQPY
Protein: Stem-loop histone mRNA binding protein (E7EUV9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPERYKRKLLINDFGRERKSSSGSSDSKESMSTVPADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAESSSEPQTSSQDDFDVYSGTPTKVRHMDSQVEDEFDLEACLTEPLRDFSAMS
Protein: Origin recognition complex subunit 2 (CeOrc2) (Q21037)
Organism: Caenorhabditis elegans
Function: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- DNA replication licensing factor MCM2
- Origin recognition complex subunit 5 C-terminal domain-containing protein
- ORC
- Origin recognition complex subunit 1
- CDT1 Geminin-binding domain-containing protein
- DNA replication licensing factor mcm-5
- Cell division control protein
- DNA replication licensing factor MCM3
- DNA replication licensing factor MCM7
- DNA replication licensing factor mcm-4
Sequence:
MPRPKILKRATVQPSAAVPVKKSTPEKEGSRQKKTNGKENASRNLQSNLEEDLEQLGFEDETVSMAQSAIENYFMQGKSASERMNNAKSRRGRRAGNGNTEEIEEDDEISNAITDFTKCDLPGLRNYITKKDNTEFEKRLEHLADNDFGKWKLYLAAGFNILLHGVGSKRDVLTEFENELSDYTYMRVDARKDGLNVKVLLGAINENMKLNCNVKRGQSTISWARSIRRKMNSQQLILIIDNIEAPDWRSDQEAFCELLENRDSVKLIATVDHIYSTFIWNSRQLSSLSFVHITINTFEIPLQELMTGDSRLLGLDARSNQSSHTMSSLDVFWKSLAVNSQKLFRLFFQMYFDTKKPVKFWDLFNAAKDDFIASTDAALRTQLVEFKDHRVLKWTRGDDGNDQLSGIVELRLVTEFLESKNMPLDEKKDE
Protein: HL02234p (RH05666p) (Vajk3) (Q9V3Z9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RH04334p
- Uncharacterized protein, isoform B
- Cuticular protein 92F
- GEO07736p1
- Cuticular protein 62Bc, isoform A
- Uncharacterized protein, isoform B
- CG10200
- Adult cuticle protein 1
Sequence:
MKVFICLAALLVASACASKTEGEKVPLEKKLDKRGLLDLGYGYGHAGLDTGYLGHGSISGHGSYGHGYGLTGYSAPAAVAVGHSGPAIAVGHTAPAVAVHHAPAPYVISKQADVHKTITITKGIPVPVHVDRPYPVVHEKRVPVEVKVPVPQPYEVIRKVPVTVKEYVKVPVPVPQPYEVIRHEKVPVHVPVDRPVPVEVPRPYPVPVAKPYPVYVEKAVNVQVPVHVDRPYPVYVKVPVVSHSVVKHAPTVAVSSYPVSAIGHDATVYSDHHGYHK
Protein: Fibroblast growth factor 21 (FGF-21) (Q9NSA1)
Organism: Homo sapiens (Human)
Function: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q9JJN1}.
Interaction partners:
- Beta-klotho
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 4
- Klotho
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Peroxisome proliferator-activated receptor alpha
- Insulin
- Mitochondrial brown fat uncoupling protein 1
- Vascular endothelial growth factor receptor 2
Sequence:
MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS
Protein: Adenylate cyclase, germination specific (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase) (Q03101)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Has a large extracellular domain which may be involved in the recognition of an extracellular signal present during germination, leading to activation or inhibition of cAMP synthesis by the cytoplasmic domain.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- 3',5'-cyclic-nucleotide phosphodiesterase regA
- Guanylyl cyclase, membrane
- F-box domain-containing protein
- Uncharacterized protein
- Ankyrin repeat-containing protein
- Protein SGT1 homolog
- Adenylyl cyclase-associated protein
- cAMP-dependent protein kinase regulatory subunit
Sequence:
MKKTFVKILSKSYVEGYPVGFFIGLIILAIFGSMVCIFSFMHYSEEENSNIQMDLERSSKQIIHNIQMNAMYLLSSIDTLKALYYVNPNFDRNDFNVFLNTTLKNSEFQYLFWIKKINNNDRNCFEEKFSKEIKDTFQIYSFDENTNSIHVAKNKSSYFPILHAFPDINKDIIGLDINSTDYMNETIKKSIFNKKPTVHLNKKVLLSKRNIDILIVSPIIVTKTLESTNETMEDMSHISSGLFLMEKNVQASRIEVENGNDFTIFLSTTNGEIVYQENYLNFKTLYQVHESGLFEDRLKYESSLKIADCVLKLWIFTTEEYENNSKTYLPLLVSIISAVILVLLITYSVDQRKQKSLIAKIMREKNNLINKILPLEVSVKLENGEDVVAERSNNACVFFLDIAGFTRFSSIHSPEQVIQVLIKIFNSMDLLCAKHGIEKIKTIGDAYMATCGIFPKCDDIRHNTYKMLGFAMDVLEFIPKEMSFHLGLQVRVGIHCGPVISGVISGYAKPHFDVWGDTVNVASRMESTGIAGQIHVSDRVYQLGKEDFNFSERCDIIHVKGKGRMKTWYLMGKKSSDFSLKKDFSRSRVQPSLFNRKQSHVHCIYPEFPSGLQALNIENNLNNTDAGCENCSKILKKTYAYSPDHSTSNYYYHGDDNSPPPPSLNSNDLIDGSEYHDDPFPSDSNVGYHDTSKDIKEDENEQNETLLFNQEQLKKKQIENIQRDLSLNDSIEAIKILNNNNNNNINDNNINNTNLNNNNNDININNSDNVNNYENNNNFSDKIENNDGDNNNINDNNYKSTNENNIKSKTLFKDSKSLINDIKMAKENCDNNDDNNNNNNNNNNNNNNDENVESKKNK
Protein: Putative pachytene checkpoint protein 2 (Q09535)
Organism: Caenorhabditis elegans
Function: Plays a key role in chromosome recombination during meiosis.
Interaction partners:
- Mitotic spindle assembly checkpoint protein MAD2A
- Cytochrome c domain-containing protein
- Exonuclease 1
- Maternal embryonic leucine zipper kinase
- WD repeat-containing protein fzy-1
- Kinetochore protein Nuf2 homolog
- Meiotic recombination protein spo-11
- DNA replication licensing factor MCM7
- Origin recognition complex subunit 1
- Double-strand break repair protein mre-11
Sequence:
MHEPMKTLKNIHAEIRICQKFPKSTVQKRFSEFEELIKAASKNARNWKPISSVELFQGDSSLNELFEKLVIGTCELRDGELFENVNDLTINPSNIHVYKLHKDGPLSQNIGDDDGDESIIGSQLWQLPCVEFDSIWENLIYDSNLKNEVMSYVAALARLSEKHVNTKIINVNRLILLTGPPGTGKTSLCKGLAQHLSIRMNDKYSKSVMLEINSHSLFSKWFSESGKLVQKMFDQIDELAEDEKCMVFVLIDEVESLGMCRESSSSRSEPSDAIRAVNALLTQIDRIRRRDNVLILCTSNLESTLDKALVDRADIVKNVGQPSDFARYSMLKSSIMELARIGVVIDNEVHTDYWPQDICDTKAPRNEFTEILFKIAQEARGLSGRAISMLPTLVYSKSPEETITLPNCMNLFLEAVKERLSRNN
Protein: Adenine nucleotide alpha hydrolases-like superfamily protein (RD2 protein) (Q94II5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Coatomer subunit zeta
- Uncharacterized protein At5g65300
- 50S ribosomal protein L20
- DDB1- and CUL4-associated factor 13
- Homeobox-leucine zipper protein HAT22
Sequence:
MEALPEDEEYSFREVVLPSLIPVVPEPELERESGERRRGRDVIVAVDHGPNSKHAFDWALVHFCRLADTLHLVHAVSSSFSLQCVKNDVVYETSQALMEKLAVEAYQVAMVKSVARVVEGDAGKVICKEAEKVKPAAVIVGTRGRSLVRSVLQGSVSEYCFHNCKSAPVIIVPGKEAGDESIVDWTRSEDPKP
Protein: Uncharacterized protein C3F10.06c (Q10181)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- tRNA wybutosine-synthesizing protein 3
- Multisubstrate pseudouridine synthase 7
- Exportin-T
- tRNA
- Putative tRNA pseudouridine synthase C25B8.05
Sequence:
MDEFDPLDAVQQIHVQARHPKNRLLSIAHDAKFVDSVIASYPTFKPVVNERCGTWYVNRRHAPISVYFKSTDGHTGQWSFSCRRLNLHLLNEITTCDGLIIVDSTRRGKRMPDALSKTIPIWIATLNKCVFERLRPHSFPNARLAFLPPFLPDTEKSSILQRLDGFVDSLMQSGIDLDALAAKLTKPIRPLWVTPASRLTSAQFEEYFTVVLVTASAQVQNGYSREHGFLYVQGAADDEEEWSHGLTPEVFWQNTESILTCPEEQLEQKISLLLSSTRNSPTMSNSSLTHLLPTPIFVGDVTGFYPPPENTSYFVLNLSNTTLNVKNELCFPIPSGKKGAPVFRKHFPSILQELNSLDPPFYERDAIFIVDEGNAKEAASCLALMILCLYYDLHMHLLAHPISLSASQSHLTKQTVRQFLVKITELHSKTNPSRAFLLAVNSLLLSANTIATS
Protein: Eyes absent homolog (EC 3.1.3.48) (A0A2R8YGM9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEDPRGINGQSVQTSQASSDVAVSSSCRSMEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSKPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL
Protein: Biotin--protein ligase 1, chloroplastic (EC 6.3.4.-) (Holocarboxylase synthetase 1) [Includes: Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)] (Q9SL92)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a major role in biotin-dependent carboxylase biotinylation. Catalyzes the addition of biotin to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase. Can also biotinylate methylcrotonyl-CoA carboxylase. Is responsible for most, if not all, biotin--protein ligase activity in Arabidopsis. Is essential for plant viability and required for ovule development.
Subcellular location: [Isoform 1]: Plastid, chloroplast {ECO:0000269|PubMed:18156294}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol {ECO:0000269|PubMed:18156294}.
Interaction partners:
- Biotin synthase, mitochondrial
- Biotin--protein ligase 2
- Probable acyl-activating enzyme 17, peroxisomal
- Holocarboxylase synthetase
- Acetyl-CoA carboxylase 2
- Acetyl-CoA carboxylase 1
- Pantoate--beta-alanine ligase
- Biotin carboxylase, chloroplastic
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
- RING/FYVE/PHD zinc finger superfamily protein
Sequence:
MEAVRSTTTLSNFHLLNILVLRSLKPLHRLSFSFSASAMESDASCSLVLCGKSSVETEVAKGLKNKNSLKLPDNTKVSLILESEAKNLVKDDDNSFNLSLFMNSIITHRFGRFLIWSPRLSSTHDVVSHNFSELPVGSVCVTDIQFKGRGRTKNVWESPKGCLMYSFTLEMEDGRVVPLIQYVVSLAVTEAVKDVCDKKGLPYIDVKIKWPNDLYVNGLKVGGILCTSTYRSKKFNVSVGVGLNVDNGQPTTCLNAVLKGMAPESNLLKREEILGAFFHKFEKFFDLFMDQGFKSLEELYYRTWLHSEQRVIVEDKVEDQVVQNVVTIQGLTSSGYLLAVGDDNQMYELHPDGNSFDFFKGLVRRKI
Protein: Transmembrane protein 41 homolog (Protein stasimon) (Q9VX39)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required in cholinergic neurons, but not in motor neurons, for normal neurotransmitter release by motor neurons. Involved in muscle growth.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Actin maturation protease
- Zinc finger protein 830
- LD03691p
Sequence:
MSYCSGVAISADEGITMRNGRAKALQEHSPDQVATPLLPQVPPQEQQDLNPQQQQQQQQQQQATPQKQAMSADEKKATKKSLVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKIPRDIQDAKMLAKVLDRYKDMYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLICFCSALGATLCYTLSNLVGRRLIRHFWPKKTSEWSKHVEEYRDSLFNYMLFLRMTPILPNWFINLASPVIGVPLHIFALGTFCGVAPPSVIAIQAGKTLQKMTSSSEAFSWTSMGILMACACASLLPGLLKNKFKHKKEA
Protein: Endochitinase 4 (EC 3.2.1.14) (Chitinase class IV) (CJP-4) (allergen Cry j Chitinase) (Q5NTA4)
Organism: Cryptomeria japonica (Japanese cedar) (Cupressus japonica)
Function: Has endochitinase activity. Hydrolyzes chitin oligosaccharides, GlcNAc(n), with different degrees of polymerization (n=2-6), a soluble substrate glycol chitin, and an insoluble substrate beta-chitin nanofiber in vitro. GlcNAc(6) is hydrolyzed at the second glycosidic linkage from the reducing end in addition to the middle linkage. GlcNAc(4) is further hydrolyzed to GlcNAc(2). Has antifungal activity against hyphal growth of H.rufa.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P29022}.
Interaction partners:
Sequence:
MQIMATQNSKSNIFWSSSASVVLVLLLLVDVGVCQNCGCNGLCCSQYGYCGSGEAYCGAGCKEGPCSSSSPPSTGTGVGSIVSSDVFNSIVGGAASGCAGNGFYTYDSFISAANAFNGFGTSGSSDVNKREIAAFFANAAHETGGFCYIEEQNPTSIYCDASNTQYPCASGKTYHGRGPLQLSWNYNYGAAGSYIQFDGLNNPEIVGTDSTISFKTAVWFWMVNSNCHTAITSGQGFGATIRAINSMECDGGNAATVASRVNYYQKFCQQLNVDTGSNLQC
Protein: Metalloprotease LoiP (EC 3.4.24.-) (P25894)
Organism: Escherichia coli (strain K12)
Function: Metalloprotease that cleaves substrates preferentially between Phe-Phe residues. Plays a role in response to some stress conditions. Seems to regulate the expression of speB.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:17909889, ECO:0000269|PubMed:22491786}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:17909889, ECO:0000269|PubMed:22491786}. Note=Proper membrane localization can depend on BepA.
Interaction partners:
Sequence:
MKIRALLVAMSVATVLTGCQNMDSNGLLSSGAEAFQAYSLSDAQVKTLSDQACQEMDSKATIAPANSEYAKRLTTIANALGNNINGQPVNYKVYMAKDVNAFAMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASAGGIVGSLSQSQLGNLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLAKLEEGRQSSMFDDHPASAERAQHIRDRMSADGIK
Protein: PPP2R1A-PPP2R2A-interacting phosphatase regulator 1 (PABIR family member 1) (Q96E09)
Organism: Homo sapiens (Human)
Function: Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin-mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.
Subcellular location: Nucleus {ECO:0000269|PubMed:33108758}. Cytoplasm {ECO:0000269|PubMed:33108758}. Note=The CHEK1-mediated Ser-37 phosphorylated form is sequestered by 14-3-3 proteins in the cytoplasm and fails to translocate to the nucleus, where it otherwise inhibits serine/threonine-protein phosphatase 2A. {ECO:0000269|PubMed:33108758}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- PABIR family member 2
- Calcipressin-1
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
- Protein phosphatase 3 catalytic subunit alpha
Sequence:
MAQEKMELDLELPPGTGGSPAEGGGSGGGGGLRRSNSAPLIHGLSDTSPVFQAEAPSARRNSTTFPSRHGLLLPASPVRMHSSRLHQIKQEEGMDLINRETVHEREVQTAMQISHSWEESFSLSDNDVEKSASPKRIDFIPVSPAPSPTRGIGKQCFSPSLQSFVSSNGLPPSPIPSPTTRFTTRRSQSPINCIRPSVLGPLKRKCEMETEYQPKRFFQGITNMLSSDVAQLSDPGVCVSSDTLDGNSSSAGSSCNSPAKVSTTTDSPVSPAQAASPFIPLDELSSK
Protein: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) (E0SLE6)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Interaction partners:
- 2,3-dihydroxybenzoate-AMP ligase, chrysobactin biosynthesis
- isochorismatase
- isochorismate synthase
- Ferrichrysobactin receptor
- NADH-quinone oxidoreductase subunit C/D
- Chrysobactin synthetase cbsF
- Iron
Sequence:
MSVTLDFSGKQVWVTGAGRGIGYDIACRFSEAGATVTGFDRAFSDGEPPFRAVELDIGDHAAVADVCATLLAKTPRLDVLVNGAGILRMGQTETLSQQDWLDCLTVNAGGAFHLFQALIPQFQQQRSGAIVSIGSNAAHVPRVGMAAYCASKAALRSLCLTVGLELAPYGVRCNMVSPGSTDTPMQRSLWHSPASEQHTIAGFPEQFKLGIPLGKIARPREITDAVLFLASDLASHVTLQDMVIDGGATLGA