wanglab/gogpt-training-data huggingface dataset:
Protein: TATA box-binding protein-like 2 (TBP-like 2) (TATA box-binding protein-related factor 3) (TBP-related factor 3) (Q1JPY4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: TATA box-binding transcription factor (By similarity). Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis. Commits mesoderm to the hematopoietic lineage during hemopoiesis, acting via mespa. Binds to the mespa promoter.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q5UE94}.
Interaction partners:
- Transcription initiation factor TFIID subunit 3
- BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.
- Transcription initiation factor TFIID subunit
- TAF7 RNA polymerase II, TATA box-binding protein
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 9
- TAF11 RNA polymerase II, TATA box-binding protein
Sequence:
MNMDEEASLESYFDQTIAGSSDYIFEGDLGLQGSTSQLQDSSFLSSLASQEKDLTEDLDLSFLPDELSTQDEPSQVEKESKNEDSGIYTDCPQKESTQADIDTSNSAQNTSQFNLPMTPMTPMTPMTPVAESSGIIPQLQNIVSTVNLACPLDLKSIALQARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVCFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFRKQ
Protein: OTU domain-containing protein 3 (EC 3.4.19.12) (B1AZ99)
Organism: Mus musculus (Mouse)
Function: Deubiquitinating enzyme that hydrolyzes 'Lys-6'-, 'Lys-11'- and 'Lys-48' linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains. Important regulator of energy metabolism. Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation. In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:35675826}. Nucleus {ECO:0000269|PubMed:35675826}. Note=Glucose or fatty acid promote nuclear translocation upon acetylation. {ECO:0000269|PubMed:35675826}.
Interaction partners:
- Large ribosomal subunit protein bL32m
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL20m
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein bL17m
Sequence:
MSRKQAAKSRPGSGGRRAEAERKRDERAARRALAKERRNRPDPGGSGCEEEFVSFANQLQALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIRQREDFEPFVEDDIPFEKHVASLSKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTDKGSTRELHIAYRYGEHYDSVRRINDNSEAPAHLLTDFQMLHQDGANKKEKMKTKGVDVKDGLRDDVEDAVHKVGSATGCTDFNLIVQNLEAENYNIKSAITALLQVNQGTGNDAEENHEPGDRVKQRGPSREEAGSGRRLSGNQGRNEGRMETSEARASPAEESKAHKSQLPKVTNKQRREQQRLEKKKRQEERHRLKALENRNGSRDTGRSEADMNTQVTLVKTFAALNI
Protein: DNA-binding protein inhibitor ID-3 (ID-like protein inhibitor HLH 462) (Inhibitor of DNA binding 3) (Inhibitor of differentiation 3) (P41133)
Organism: Mus musculus (Mouse)
Function: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:16556596}. Cytoplasm {ECO:0000269|PubMed:16556596}. Note=Nuclear in proliferating cells, translocates to cytosol during cell differentiation.
Interaction partners:
- Transcription factor E2-alpha
- Transcription factor 4
Sequence:
MKALSPVRGCYEAVCCLSERSLAIARGRGKSPSTEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELTPELVISKDKRSFCH
Protein: Tetraspanin-4 (Tspan-4) (Transmembrane 4 superfamily member 7) (Q9DCK3)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MARGCLQGVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGNFATLSSSFPSLSAANLLIVTGTFVMAIGFVGCIGALKENKCLLLTFFVLLLLVFLLEATIAVLFFAYSDKIDSYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSDSCGLHEPGTWWKSPCYETVKAWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTYCA
Protein: Zinc finger protein 746 (A0A2R8YDQ5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEAVAAPISPWTMAATIQAMERKIESQAARLLSLEGRTGMAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGESPKVPVTFDDVAVYFSEQEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPEVLSQIEQGKEPCNWRRPGPKIPDVPVDPSPGSGPPVPAPDLLMQIKQEGELQLQEQQALGVEAWAAGQPDIGEEPWGLSQLDSGAGDISTDATSGVHSNFSTTIPPTSWQTDLPPHHPSSACSDGTLKLNTAASTEDVKIVIKTEVQEEEVVATPVHPTDLEAHGTLFGPGQATRFFPSPAQEGAWESQGSSFPSQDPVLGLREPARPERDMGELSPAVAQEETPPGDWLFGGVRWGWNFRCKPPVGLNPRTGPEGLPYSSPDNGEAILDPSQAPRPFNEPCKYPGRTKGFGHKPGLKKHPAAPPGGRPFTCATCGKSFQLQVSLSAHQRSCGAPDGSGPGTGGGGSGSGGGGGGSGGGSARDGSALRCGECGRCFTRPAHLIRHRMLHTGERPFPCTECEKRFTERSKLIDHYRTHTGVRPFTCTVCGKSFIRKDHLRKHQRNHAAGAKTPARGQPLPTPPAPPDPFKSPASKGPLASTDLVTDWTCGLSVLGPTDGGDM
Protein: Neurexin 1 (A0A0R4J2G7)
Organism: Homo sapiens (Human)
Subcellular location: Presynaptic cell membrane {ECO:0000256|ARBA:ARBA00035005}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00035005}.
Interaction partners:
Sequence:
MGTALLQRGGCFLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV
Protein: Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2) (Q91WK0)
Organism: Mus musculus (Mouse)
Function: May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity).
Interaction partners:
- Protein flightless-1 homolog
Sequence:
MGTPGSGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQREGVEDTLSLRSLGSHRLDEKSDKQYAENYTRPSSRNSASATTPLSGQSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMDELKEGLRQRDELIEKHGLVIIPDSTPNGDVHHEPVVGAITAVSQEAAQVLESAGEGPLDVRLRKLAGEKDELLSQIRKLKLQLEEERQKCSRNDGMSGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDIATLEQSISRLEGQVLRYKTAAENAEKIEDELKAERRKLQRELRTAQDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ
Protein: Vomeronasal 2, receptor 120 (A0A3Q4EI01)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MLIFVSVLLFLNFPVASCEPINPGCSLGMADAIFQDGDVLVDCHFVLLTVSIALQKIFHFLRFHLSFPMFIYRIHPNKYQYVIALNFAIEEINKNIHLLPNISLGYDMYSIVQYQATILEHSIRFLTGLKEAIPNYTCRKESKLIAVVTGTSWEFPSRISTILGLYKYPQNPLGLFEIYGIVFFTSLHIFFSHQLTFGPFDPMLSDHVKFPFIYQMAPEDTSLALGMVSLMVHFSWTWVGLIITENEKGIKFLSDLKREMKKNSVCAAFVQMLSLKYRYNWNDLLSTDPAIMGEMVKVFIVFADIDSTLVVIFKASGQVDPWRVWVTTSQWDIASSVRHFILDSFHGTLIFSQHHPEISAFKDFIQTVNPSKYPDDIFLSHIWKMYLNCPFSRVYCKTLKTCSSNGSLALLPWHRFDMDMSEESYHIYNAVYAVAHSLHEMLQEHADVQPVKSRKRLVFSPCRTPLSVCSTSCAPGLMKSPQEGKASCCFDCHPCLENEISNETDSIQCIKCPDDQYANTEQTHCIPKAVTFLAYEDPLGMALACMALCFSALTALVLGVFVKHHETPIVKANNRTLSYILLISLILCFLCSLPFIGLPNMATCILQQMSFGVVFTIAVSTVLAKTVTVVLAFRSTVPGRRMRWILVSPNLIIPICTLIQMVLCAIWLGASAPFVDINAHNERGHITIMCNKGSATAFYCVLGYLGFLAMGTLTVAFWARNLPDIFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKVMVAVEVFSILASSAGLLGCIFVPKCYIILIRPKNGSFKGLRGTRVCK
Protein: HTH-type transcriptional regulator EcpR (P71301)
Organism: Escherichia coli (strain K12)
Function: Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Positively regulates the expression of the ecp operon (By similarity). Also represses expression of the flagellar master operon flhDC, and consequently prevents flagellum biosynthesis and motility. Acts by binding to the regulatory region of the flhDC operon (Probable).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Common pilus major fimbrillin subunit EcpA
- Probable fimbrial chaperone EcpB
- Probable fimbrial chaperone EcpE
- Probable outer membrane usher protein EcpC
- Transcriptional activator protein BglJ
- Fimbria adhesin EcpD
- Transcriptional regulatory protein RcsB
Sequence:
MTWQSDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLSTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELVYVINGRFLRKDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTVYTHRRNAEAKLYSKIYKLVQ
Protein: US3 protein Ser/Thr kinase long isoform (EC 2.7.1.-) (Q5PP90)
Organism: Suid herpesvirus 1 (SuHV-1) (Pseudorabies virus)
Interaction partners:
Sequence:
MLAMWRWVTKRSRLRRGHAHLGGNKGVRGICSLYLAGLSRGLSRVHAQRSHAATMADAGIPDEILYSDISDDEIIIDGDGDSSGDEDDDDGGLTRQAAARIVTDLGFEVLQPLQSGSEGRVFVARRPGEADTVVLKVGQKPSTLMEGMLLQRLSHDNVMRMKQMLARGPATCLVLPHFRCDLYSYLTMRDGPLDMRDAGCVIRAVLRGLAYLHGMRIMHRDVKAENIFLEDVDTVCLGDLGAARCNVAAPNFYGLAGTIETNAPEVLARDRYDTKVDVWGAGVVLFETLAYPKTITGGDEPAINGEMHLIDLIRALGVHPEEFPPDTRLRSEFVRYAGTHRQPYTQYARVARLGLPETGAFLIYKMLTFDPVRRPSADEILNFGMWTV
Protein: F20D23.9 protein (IAP-like protein 1) (Q9SHI0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- E3 ubiquitin-protein ligase BOI
- Cell division cycle protein 27 homolog B
Sequence:
MKEEDVSSQNVNPRSNRNSVASASASASATPVDRFRRRARSPSPPQTAAASSAGASSPAVLVNAGSVDWTGHGLALSVRSCRTWDRGDLLRRLATFKPSNWLGKPKTASSLACAQKGWVSVDLDKLQCEYCGSILQYSPPQDSLNPPEADTTGEKFSKQLDDAHESSCPWVGKSCSESLVQFPPTPPSALIGGYKDRCDGLLQFYSLPIVSPSAIDQMRASRRPQIDRLLAHANDDLSFRMDNISAAETYKEEAFSNYSRAQKLISLCGWEPRWLPNIQDCEEHSAQSARNGCPSGPARNQSRLQDPGPSRKQFSASSRKASGNYEVLGPEYKSESRLPLLDCSLCGVTVRICDFMTTSRPVPFAAINANLPETSKKMGVTRGTSATSGINGWFANEGMGQQQNEDVDEAETSVKRRLVSNVGLSFYQNAAGASSSAQLNMSVTRDNYQFSDRGKEVLWRQPSGSEVGDRAASYESRGPSTRKRSLDDGGSTVDRPYLRIQRADSVEGTVVDRDGDEVNDDSAGPSKRTRGSDAHEAYPFLYGRDLSVGGPSHSLDAENEREVNRSDPFSEGNEQVMAFPGARDSTRASSVIAMDTICHSANDDSMESVENHPGDFDDINYPSVATAQSADFNDPSELNFSNQAQQSACFQPAPVRFNAEQGISSINDGEEVLNTETVTAQGRDGPSLGVSGGSVGMGASHEAEIHGADVSVHRGDSVVGDMEPVAEVIENLGQSGEFAPDQGLTDDFVPAEMDREGRLGDSQDRVSQSVVRADSGSKIVDSLKAESVESGEKMSNINVLINDDSVHPSLSCNAIVCSGYEASKEEVTQTWESPLNAGFALPGSSYTANDQGPQNGDSNDDIVEFDPIKYHNCYCPWVNENVAAAGCSSNSSGSSGFAEAVCGWQLTLDALDSFQSLENPQNQTMESESAASLCKDDHRTPSQKLLKRHSFISSHGKK
Protein: Uncharacterized oxidoreductase YNL181W (EC 1.-.-.-) (Potentiates bioactive compound response protein 1) (P53878)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14690591}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- F-box protein YLR352W
- SWIRM domain-containing protein YOR338W
Sequence:
MPLNIIGTALLDGTDKIPYYQTIKKVAPYVLATGAIKYWSRGPSNTWERKLHGKVYLVTGATSQGMGTSVAYKMAELGAQLIILTREVDEWVTEWCEELREKTKNELIFVEKCDLSNLWEIRKFATSWLDNSPPRRLDGVIVMSGDMEPWGIPKISLPQRRSSKDGLELQIATNYVAIFHLLNLLQPSFKAQPPDRDVRIILATCWLQVVGDINIEDPLWQNAKYKSALKFFASSKLQLGLSMMELQRRLTEDIKNQKTNGAERTGKNVTITMVQPGTMRSNSLRRVISNGSVVLLIILYCILLYPILWLFTKSGRRGDQSFLYALMTPELEEVNLKDTKVKYISDCSIVKFARKEFDDEELQKKLFDNTERDILQLEKKVAAKRNANKTGNQNSKKKSQNKSRKDD
Protein: Dehydration-responsive element-binding protein 3 (Protein TINY 2) (Q9LYD3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MAEEYYSLRSERVTQLLVPNSESDSVSDKSKAEQSEKKTKRGRDSGKHPVYRGVRMRNWGKWVSEIREPRKKSRIWLGTFPTPEMAARAHDVAALSIKGTAAILNFPELADSFPRPVSLSPRDIQTAALKAAHMEPTTSFSSSTSSSSSLSSTSSLESLVLVMDLSRTESEELGEIVELPSLGASYDVDSANLGNEFVFYDSVDYCLYPPPWGQSSEDNYGHGISPNFGHGLSWDL
Protein: Zinc finger protein MSN2 (Multicopy suppressor of SNF1 protein 2) (P33748)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Positive transcriptional factor that acts as a component of the stress responsive system. Recognizes and binds to the stress response element (STRE) which is involved in the response to various forms of stress (heat, oxidative, osmotic, etc.). Involved in the regulation of the CTT1, DDR2, HSP12 genes. May be regulated via WHI2-PSR1 complex phosphatase activity.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Serine/threonine-protein kinase RIM15
- Serine/threonine-protein kinase SCH9
- Zinc finger protein MSN4
- Ras-like protein 2
- Transcriptional activator/repressor GIS1
- Mitogen-activated protein kinase HOG1
- cAMP-dependent protein kinase type 2
- cAMP-dependent protein kinase type 1
- cAMP-dependent protein kinase type 3
- Carbon catabolite-derepressing protein kinase
Sequence:
MTVDHDFNSEDILFPIESMSSIQYVENNNPNNINNDVIPYSLDIKNTVLDSADLNDIQNQETSLNLGLPPLSFDSPLPVTETIPSTTDNSLHLKADSNKNRDARTIENDSEIKSTNNASGSGANQYTTLTSPYPMNDILYNMNNPLQSPSPSSVPQNPTINPPINTASNETNLSPQTSNGNETLISPRAQQHTSIKDNRLSLPNGANSNLFIDTNPNNLNEKLRNQLNSDTNSYSNSISNSNSNSTGNLNSSYFNSLNIDSMLDDYVSSDLLLNDDDDDTNLSRRRFSDVITNQFPSMTNSRNSISHSLDLWNHPKINPSNRNTNLNITTNSTSSSNASPNTTTMNANADSNIAGNPKNNDATIDNELTQILNEYNMNFNDNLGTSTSGKNKSACPSSFDANAMTKINPSQQLQQQLNRVQHKQLTSSHNNSSTNMKSFNSDLYSRRQRASLPIIDDSLSYDLVNKQDEDPKNDMLPNSNLSSSQQFIKPSMILSDNASVIAKVATTGLSNDMPFLTEEGEQNANSTPNFDLSITQMNMAPLSPASSSSTSLATNHFYHHFPQQGHHTMNSKIGSSLRRRKSAVPLMGTVPLTNQQNNISSSSVNSTGNGAGVTKERRPSYRRKSMTPSRRSSVVIESTKELEEKPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTHKKHGDI
Protein: Phosphatidylinositol N-acetylglucosaminyltransferase (A0A1D8PHD4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Phosphatidylinositol N-acetylglucosaminyltransferase
- Phosphatidylinositol N-acetylglucosaminyltransferase
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit
- Phosphatidylinositol N-acetylglucosaminyltransferase
- N-acetylglucosaminylphosphatidylinositol deacetylase
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- GPI mannosyltransferase 2
- GPI-anchor transamidase
- GPI mannosyltransferase 4
Sequence:
MIFHFNQKEKADSSKCKTIHVRKSIENWAIILLYILFVWYRKSELHYDHIIHTNFWGVEKNKPPFLFQTKNSIPQLLQFSIPTQPTAITQTMSYHLNILSVLSRSPSPSPQPQPQPSQQQLSSSSSHPDPAPEDDKLARESDVTVSNITSSSEAEYRGFSIHIISTIGLIIWIIWTLLPDSLLHKLSIDYYPNKYWSIAIPSYSLMLMLFAYWVFALYNTEVLTLPLNDIHCIIDENSVFPGEKKVSQVEKQEEEEGEEEDMGGGDDSIMENSIEFIHKAPSGVWDLPITLVNDVLYE
Protein: Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member) (A0A024R274)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU361195}. Nucleus {ECO:0000256|RuleBase:RU361195}.
Interaction partners:
Sequence:
MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTMPIADPQPLD
Protein: Heat shock protein homolog SSE2 (P32590)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a calcium-dependent calmodulin-binding activity.
Interaction partners:
- Hsp70 nucleotide exchange factor FES1
- ATP-dependent molecular chaperone HSP82
- Heat shock protein 104
- HSP70 co-chaperone SNL1
- Heat shock protein homolog SSE1
- ATP-dependent molecular chaperone HSC82
- Heat shock protein STI1
- Protein SIS1
- Heat shock protein 78
- Mitochondrial protein import protein MAS5
Sequence:
MSTPFGLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKRIIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETKSSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIGLVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAYNRILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAKLTVNDIDFVEIIGGTTRIPVLKKSISDVFGKPLSSTLNQDEAVAKGAAFICAIHSPTLRVRPFKFEDIDPYSVSYTWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMKAVYTHPSKLPKGTSTTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLPEDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALEEYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELASLGNIIRGRYLAKEEEKRQALRANQETSKMNDIAEKLAEQRRARAASDDSDDNNDENMDLD
Protein: Heterodisulfide reductase, putative (Q72DT1)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Heterodisulfide reductase, iron-sulfur-binding subunit, putative
- Hydrogenase, iron-sulfur cluster-binding subunit, putative
- Heterodisulfide reductase, B subunit
- Heterodisulfide reductase, transmembrane subunit, putative
- Adenylyl-sulphate reductase, alpha subunit
- Uncharacterized protein
- Adenylylsulphate reductase, beta subunit
- Heterodisulfide reductase, C subunit
- Pyridine nucleotide-disulfide oxidoreductase
- Glutamate synthase, small subunit
Sequence:
MSNSILVVGGGFSGLTAAIEAAEVGYEVFIVEKSPFLGGRVAQLNKYFPKLCPPSCGLEIQFQRIKKNPNIKFFTQAQVTAVKGEKGNYTVSVRIEPRHTVPNSADLSMLAGALEGEVENEFELGLAKRKPLYLSTPFAFPNRYVLDKNALSQADQLKVGASAFCDLNEGPREIELSVGSIVLATGWKPYDVTNLSNLGAGKIANCVSNMQLERLAAACGPTKGAITRPGDGKSPRKIAFVQCAGSRDQNHLNFCSYICCMASLKQALYVREQYPDAEVTVYYIDLRTPGRYDKFMRKVRADEKINLVKGKVAGVEEDTATGDVIVEVEDAVKGEKRKVRYDMVVLATGMQPSLAGQKLPFDVPVDEDGFIVGGEEKGIFAAGCAQKPLDVMRSAQSGTSAALKAIQTVRGR
Protein: Phospholipid-transporting ATPase dnf1 (EC 7.6.2.1) (Q9UT43)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q12674}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000250|UniProtKB:Q12674}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Actin cytoskeleton-regulatory complex protein sla1
Sequence:
MKSSGIAGDSNGFETNFLNETTNREEDGAFNWNAADDGTNERREDIHVRFQDSALPLGIDENELDEIDINGDSKKLDSVEVDESHDVNSPSDSRLKSSFKSVLELTANSMVSVLTPSTKTEQTSKGKGKKKKAHVSFLEGPVEEIPLDDIEPTSPREASPVFNGRPPIPPEFLKSRHKEFTIPNPLQFISNFLSNLFSRDTRYLKSSHGRIIIINPYDDSSQIDERTGKPYMQNSIVSSRYNKYNFVPLQIIAQFSKTANCYFLLIAIMQMIPGWSTTGTYTTIIPLLIFISIAILREGFDNYRRYRQDRVENRIQTQVLRHVDVDPPIVEEHSSFFRRRRWRRSRSQESASRSTIRSTDEREPERTSEDPPQLPPSPSSPSSPALSVKPNIDPQPPLYNSTLTTTRSIPANKPTFFWASCDRKDVRVGDIIRLTSDQTLPADVIALSSPNPNGAIYIETAALDGETSLKTRLVNSTLRSLCKDINDLIRLSGTCTVEDPNGDLYNFNGSMKLDSIQGEIPLSNNDVLYRGSNLRNTSELFALVIFTGEESKIRMNAVRNVSVKAPSMQKVTNRIVIFIFALVVSMAIYCTAAYFVWQKKVERKLWYLTNSKLSFVPILVSFIILYNTMVPISLYVSMEIIRVFQTFLVQSDIDLYYPENDTRCEVRSSSILEELGQVTHVFSDKTGTLTDNIMLFRNLSVGGFAWQHVGAENPKLVSTSQKSDDLDGEAKPPQLENIQGTTIQLLQYVHDNPHTTFSKRVRIFLLNLAICHTCLPSFDEENQIYKYQSISPDELALVHAAQQLGYIVIDRDIDSLTIRLHYPLDPHSHPIAKTYRILNIIEFTSKRKCMSVIVRMPNGRICLFCKGADSAIIKRLRLSNLAKRKDKSVTKAEQARKSIEIDKAIIRNSQSTSRPSLTASRPSLSRRRNDYINNVTSWLDERREKMGVVRPRASTSILETRRRPAVGRHSLAGGERLMEDKKYLSKQEEAEGSIYESLNHNDAKLFENTFEHVHAFATDGLRTLMYAHRFIDESEYQSWKLVNDAALNSLSNRQQLLDEAADLIEKDLEFAGATAIEDKLQVGVPESINSLFRAGIKFWMLTGDKKETAINIGHSCGVIKEYSTVVVMGSLDGVEGSDETVSGGQRLSLDRPPTNDPASLMIHQLISCMNAIHSNSLAHLVIVIDGSTLADIENDPELFLLFINTAVEADSVICCRSSPMQKALMVQKVRNTLEKAVTLAIGDGANDIAMIQEAHVGIGIAGREGLQAARSSDFSIGRFKFLIKLLFCHGRWSYVRLSKYILGTFYKEQFFFLMQAIMQPFVGYTGQSLYESWGLTCFNTLFSSLCVIGLGIFEKDLSASTVIAVPELYQKGINNEAFNWRVYFGWCSIAFIQAFLVFYVTYSLFGMKELNDNNIFAYGQLIFTAAIFIMNFKLVFIEMQYINIISIIVLVLTSLAWFLFNIFISEHYPDKNLYLARSQFLHHFGKNPSWWLTMLFVMVCALTIDIVAQMLRRTLRPTDTDIFVEMENDAFVRSRFEQESGEFLQANAPSVDEIEQYLKSRD
Protein: G protein-coupled receptor 132b (Probable G-protein coupled receptor 132b) (A0A0R4IEK2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MVSGRVLTTFRDMMHATTVAQSIMTSMNQSSRASCEISHEADRIPLMVLYIVVFIIGLPANLATVYLTLHQVCRKNVLGIYLLSLSICDLTYLFTLPMWTVYVSRNHEWPWSSLACKITGFVFFNNMYISIFLLCCVSIDRYVAVVYAIESRGLRQKRIAAFVSFLIFIVVGLGHSPVFIMREGQVEEGSHRCFEPSQSTTLVTGFNYARVCIGFCIPLAILIFTNRAILANVQASTGLQPHQKVKVRYLAVAVVALFLICFAPYHIILLMRAVIFHFPNLQGKCHFEQHIYTPYKISLGLSTFNSAINPILYVLSSNNIRQEIRRGITSVCDRVLSSQRSTHSSQHNMHSSRSNSEPFPIKGGQMRTVCPTA
Protein: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1) (Q9VTM2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Diphthamide biosynthesis protein 3
- 2-
- Eukaryotic translation elongation factor 2
- diphthine methyl ester synthase
- GH01248p
- Diphthamide biosynthesis 4, isoform A
- IP06473p
- Amino acid transporter transmembrane domain-containing protein
- Probable dimethyladenosine transferase-N
- Esterase CG5412
Sequence:
MLDVIQPSSNLPTSESTDIVVVRARPKKVFKPKARINRIPQELLDDPLLQQAIDRLPSNYNFEMHKTIWRIREMKAKRVALQLPEGLLMYAMVISDIVERFTSADTVIMGDVTYGACCVDDYTAKALGADLLVHYGHSCLIPVDQTCGIKVLYIFVDIKIDPLHFLDSVKLNFRPEVGQIALVSTIQFVTTLQAASTELKAAGYDVIVPQAKPLSPGEILGCTSPQLPETTKMIIYLGDGRFHLESAMIANPLLKAYKYDPYEKKFTTEQYDHSAMQNLRLDAVQRAKKARRIGIILGTLGRQGSSRVHRFLEKRLHAKGIETTTLLLSEIFPQKLALFADIDAFVQIACPRLSIDWGSAFSQPLLNPYELSVVLGDVEWTPHNSSPRNNAYPMDFYASGSLGPWTPNFKPPAIGECENKPSADCCGRCTRAELEKDDSGKAAALDDLLDFKKG