wanglab/gogpt-training-data huggingface dataset:
Protein: Immunoglobulin heavy variable 4-39 (Ig heavy chain V-II region WAH) (P01824)
Organism: Homo sapiens (Human)
Function: V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Subcellular location: Secreted {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. Cell membrane {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}.
Interaction partners:
Sequence:
MDLMCKKMKHLWFFLLLVAAPRWVLSQLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCAR
Protein: Notch ligand osm-11 (Osmotic avoidance abnormal protein 11) (O45346)
Organism: Caenorhabditis elegans
Function: Probable secreted lin-12/Notch ligand or co-ligand involved in the mediation of Notch signaling. Involved in the lin-12/Notch pathway signaling of cell fate in vulval precursor cells (VPCs), acting redundantly with dsl-1 and lag-2. Required for normal octanol avoidance response, acting via both lin-12/Notch and glp-1/Notch signaling pathways in neurons, in concert with lag-2. Involved in regulation of sleep-like quiescence during the larval to adult transition, acting via Notch receptor activation and in parallel with EGF signaling.
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:18700817}; Peripheral membrane protein {ECO:0000269|PubMed:18700817}. Note=Concentrated on the apical surface of vulval precursor cells. {ECO:0000269|PubMed:18700817}.
Interaction partners:
- Osmotic avoidance abnormal protein 8
- Protein lin-12
- Delta and OSM-11-like
- Delta and osm-11 homolog protein 1
Sequence:
MNFITVAALAIVMVLAQANPARVRRNEEMSERYCIKHLDHYNKYCGDNAGPIDRALFGKVAKFCPAYEKHCAVGKAGLVELPDLGSPLVMPPVLPRGSDFASLDLPIADERKPAHIHSSRTAPQTTRLTAAIVATCTPECTAAHCTDECKCAHTHPKVHQMCNPPSSAAMAETCQRWYSKCTMFTPVQY
Protein: Protein her-1 (Hermaphrodization of XO animals protein 1) (P34704)
Organism: Caenorhabditis elegans
Function: Dictates male development. Probably plays a direct role in cell signaling during C.elegans sex determination. Inhibits the function of tra-2a.
Subcellular location: Secreted.
Interaction partners:
- Sex-determining transformer protein 2
- XO lethal protein 1
- Sex determination and dosage compensation protein sdc-2
- Zinc finger protein sdc-1
- Zinc finger protein sdc-3
- Steroid hormone receptor family member cnr14
- Protein phosphatase fem-2
- Sex-determination protein fem-3
- Sex-determining transformer protein 1
- Sex determination protein fox-1
Sequence:
MRYLPIFVFLGSFGYTETTLTKELIKDAAEKCCTRNRQECCIEIMKFGTPIRCGYDRDPKLPGYVYKCLQNVLFAKEPKKKINLDDSVCCSVFGNDQNDSGRRCENRCKNLMTSPSIDAATRLDSIKSCSLLDNVLYKCFEKCRSLRKDGIKIEVLQFEEYCNATFIQKRTFRGV
Protein: CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5) (Q8N6W0)
Organism: Homo sapiens (Human)
Function: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- CCAAT/enhancer-binding protein delta
Sequence:
MARLTESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVAPITNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY
Protein: Nicotinate dehydrogenase large molybdopterin subunit (NDH) (EC 1.17.1.5) (Nicotinic acid hydroxylase large molybdopterin subunit) (NAH) (Q0QLF2)
Organism: Eubacterium barkeri (Clostridium barkeri)
Function: Catalyzes the hydroxylation of nicotinate to 6-hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs.
Interaction partners:
- Nicotinate dehydrogenase medium molybdopterin subunit
- Nicotinate dehydrogenase FAD-subunit
- Nicotinate dehydrogenase small FeS subunit
- Carbon-monoxide dehydrogenase small subunit
- Carbon-monoxide dehydrogenase small subunit
- Xanthine dehydrogenase FAD-binding subunit
- Carbon-monoxide dehydrogenase medium subunit
- Xanthine dehydrogenase accessory factor
- 6-hydroxynicotinate reductase
- Selenium-dependent xanthine dehydrogenase
Sequence:
MGKDYQVLGKNKVKVDSLEKVMGTAKFAADYSFPDMLYAGVFRSTVPHARIVSLDLSKARAIDGVEAVLDYHAIPGKNRFGIIIKDEPCLVDDKVRRYGDAIAVVAAQTPDLVQEALDAITIEYEELEGIFTMERALEEDSPAIHGDTNIHQVKHLEYGDVDAAFKQCDIVVEDTYSTHRLTHMFIEPDAGVSYYDNEGMLTVVVSTQNPHYDRGEVAGMLALPNSKVRIIQATTGGGFGGKLDLSVQCHCALLTYHTKKPVKMVRSREESTTVSSKRHPMTMHCKTGATKDGRLQAVQVEMFGDTGAYASYGPAVITRATVHCMGPYVVPNVRVDAKFVYTNNPMSGAFRGFGVPQASVCHEGQMNALAKALGMDPIDIRILNAHQVGAKLATGQVLENSVGLIETLEKAREKAVEVMGYEKTR
Protein: Hypoxia inducible factor 1 subunit alpha, like (Hypoxia-inducible factor 1, alpha subunit, like) (Q7T2E4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRVTLSYLRMNRLIQSGSTKSQTEKSETPTDGFYQQALAGFILVMTEEGDMVFLSESVSKYIGITQLELLGQSVYEFVHPCDQEELRDILATRPGVSKKKTMEHNFFLRMKSTLTHTGRTVNIKSATWKVLHCTGHMQPFSGDDENSPSAGSFLTLLCEPIPHPSSVEFPLDSSTFLTRHNLDLTYTQCDGRVTELVGYQPDDLIGRSAFEFFHALDFDHVSRSLHILFSKGQVCTGQYRFLAKNGGFVWTETQATVLYNSRTSQPEAVVCLNFILSGVEEQDVVFSLEQTCEKPKPKVERLMVLKEEQEDSDMEESSTAKLFLQMKENPEELLQLAPHSGDAIISLTEGLELSFCCPQSPNSVPECPQDFCTPELRKLLSPIFDGPAKSPPAASPAEELPMEMEGVEKFFALKPEESLTPKGQSEAVDELDLDMLAPYISMDDDFQLTFLPQSEITPPLEMLTSNSRKRCLEDDDDDDIPVLAARWDKKQMSGSIEDQLLLSHTLLDGLSDGSDEFEPPPQKRSQLLTDRDPLLGGVQALCDTAALMRDTFLSRPPDLRRPVAETLPSLT
Protein: Proton-coupled zinc antiporter SLC30A8 (Solute carrier family 30 member 8) (Zinc transporter 8) (ZnT-8) (Q8IWU4)
Organism: Homo sapiens (Human)
Function: Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion.
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:15331542, ECO:0000269|PubMed:16984975}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:15331542, ECO:0000269|PubMed:16984975}; Multi-pass membrane protein {ECO:0000255}. Note=Associated with insulin and glucagon secretory granules. {ECO:0000269|PubMed:15331542}.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase-like N
- Hematopoietically-expressed homeobox protein HHEX
- Threonylcarbamoyladenosine tRNA methylthiotransferase
- Insulin
- Transcription factor 7-like 2
- Glutamate decarboxylase 2
- Insulin-like growth factor 2 mRNA-binding protein 2
- ATP-sensitive inward rectifier potassium channel 11
- Alpha-ketoglutarate-dependent dioxygenase FTO-)-demethylase FTO)
- Kinesin-like protein KIF11
Sequence:
MEFLERTYLVNDKAAKMYAFTLESVELQQKPVNKDQCPRERPEELESGGMYHCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQRCLGHNHKEVQANASVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD
Protein: Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (ACIX) (Adenylyl cyclase 9) (AC9) (O60503)
Organism: Homo sapiens (Human)
Function: Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10987815, ECO:0000269|PubMed:9628827}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Adenylate cyclase type 6
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit gamma
- cAMP-dependent protein kinase catalytic subunit alpha
- Potassium voltage-gated channel subfamily KQT member 1
- Rap guanine nucleotide exchange factor 4
- Rap guanine nucleotide exchange factor 3
- Adenylate cyclase type 3
Sequence:
MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDSGGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALTLLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVSSGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKNSTKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAALAVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEYETNIHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSVLTSPLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLSPKRPWKEPVKAEERGRFGKAIEKDDCDETGIEEANELTKLNVSKSV
Protein: Mitogen-activated protein kinase ERK-A (EC 2.7.11.24) (Extracellular-regulated kinase A) (Protein rolled) (P40417)
Organism: Drosophila melanogaster (Fruit fly)
Function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway to regulate proliferation, differentiation and effect cell fate decisions in various tissues. Required downstream of phl/Raf in the sev/sevenless, tor/torso, and EGF receptor homolog Egfr signal transduction pathways. Required for embryonic epithelial tissue repair. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:1378625}. Nucleus {ECO:0000269|PubMed:1378625}.
Interaction partners:
- Dual specificity mitogen-activated protein kinase kinase dSOR1
- Raf homolog serine/threonine-protein kinase Raf
- protein-tyrosine-phosphatase
- Cell death protein hid
- Ras-like protein 1
- D-Importin 7/RanBP7
- Ets DNA-binding protein pokkuri
- non-specific serine/threonine protein kinase
- ETS-like protein pointed
- Protein mothers against dpp
Sequence:
MEEFNSSGSVVNGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDDISRDALKSLIFEETLKFKERQPDNAP
Protein: Growth hormone (A4GX95)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLLLAFTLLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
Protein: Leptin (Obesity factor) (A0A023GUT0)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MRCPGVSLWGLLCLGAAAGGGRPVRLEGLRADARALTRTLSTRLQQLQLFPLTLRLSGLEGVPEGVPEGVPEGGVPPGLGWAAQRLQLFQRLLGALPGPDPRLAQVANDLENLRSLLALLGTLLGCPPPRDPRPPPPAPLAEAPHTVAGVALARLRRCLDGVAACLEGVPAC
Protein: Guanine nucleotide-binding protein subunit alpha-15 (G alpha-15) (G-protein subunit alpha-15) (Epididymis tissue protein Li 17E) (Guanine nucleotide-binding protein subunit alpha-16) (G alpha-16) (G-protein subunit alpha-16) (P30679)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Interaction partners:
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
- Relaxin-3 receptor 2
- B2 bradykinin receptor
- Sphingosine 1-phosphate receptor 4
- Beta-adrenergic receptor kinase 1
- Guanine nucleotide-binding protein subunit beta-5
- Guanine nucleotide-binding protein subunit alpha-14
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
Protein: Putative beta-glucosidase (EC 3.2.1.21) (Beta-D-glucoside glucohydrolase) (Cellobiase) (Gentiobiase) (Q9P6J6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glucan 1,3-beta-glucosidase 1
- Alpha-glucosidase
- Glucan 1,3-beta-glucosidase
- Putative invertase
- Uncharacterized family 31 glucosidase C1039.11c
- Invertase
- Uncharacterized family 31 glucosidase C30D11.01c
- Glucan 1,3-beta-glucosidase 2
- Alpha-glucosidase
- Putative cell-type specific agglutination protein pfl7
Sequence:
MMEHDVEDLINQLDISEKAMLLSGTDLWHTAAIPRLNIPSIRLSDGPNGIRGTSFFNSSPSACFPCGTALGATFDKKLLFEVGEYLAEEAKAKGVSVVLGPTVNIHRGPLNGRGFESFSEDSTLSGLAASYVILGLQSKNVQACIKHFVCNDMEDERNSVSIDVSQRALREVYLMPFQLACKYSNFKSLMTSYNKVNGEHVSQSRILLDNILRKEWEWKGTIISDWFGTYSLKKAIDAGLDLEMPGKPRFRNVNTIQHLVGSKELSESILDERAKNVLKLVKHSWQNTEAENHCELNNDSSCLREALKKFASQSIVLLKNKKKLLPLSRKGTFAVIGPNAKVCNYSGGGSANLKPYYTVSMYDGIAAKIDGVPEYALGCHNYLNLPNIANLLVNPRTGKHGYVAKFYLEPATSENRTLIDDYDLEDGVVRFYDYCNDKMKDGYFYIDIEGYLIPDEDAVYEFGISVFGTALLFIDDVLLIDNKTKQTPTNHTFEFGTIEERNSIYLKKGRKYNVRVEYGSAATYTLSTNLSPSTGGRYSIGCVKVIDPETEIDYAVRVAKSVDCVILCVGLTAEWETEGEDRKTMTLPSLSDKLVYSILQSNPNTVVVTQSGTPIEMPWISEAHTLLHIWYNGNELGNALANIIFGEQNPCGKLPITFPKKLKDNPAYLSFRSSRGHCVYGEDVFVGYKYYEAVEREVLFPFGYGLSYTTFELSNLYLKNCGERLRIDLEISNTGPMSGAEIIQVYISQIVRSVNRPVKELKEFSKVVLCPKETKLIRIELDIKYATSFYDELNEKWCSEEGEYNVLVGTSSKDIALTGKFTLPKTIHWTGL
Protein: ABC transporter H family member 2 (Q8T664)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MAQVFPDVIEEKIQDDDKFFGQTRLKNDDIDFNDPDNVLTMKNIHKTYLLGIEGVPALRGVSMAIKRGEFICIFGTSGGGKTTMLNIIGTIDKPTKGEMKLCGKTINHKTTDKDLAFLRLRNIGFVFQTFNLLSSLTALENVEMPMILLGELSASERRERAISLLTKVGMKDRLDHFPSQLSGGEQQRVTIARAIANNPDVLLLDEPTGDLDTVNTSVIMKLLTDLNKQENITLIMVTHDVGLKMYSDRIIWMRDGKIQRIETVQEQSKREHYQKLYKECELINQNQKNGVTSVFKNDDDNKNIKKQGTLTEFRRPTDYKSIASYNNNNSNLNNNSNSNSNNNSNNNNSKNYASSSSSSSVLNGKLSQSTVNNSSIYNHNNDSPFFNSNNNNNINNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNSNSNNNNNNTKSNNNNNNNIFDIASSSSSYSNNNNNSKNNSLIDDIYLDINEGSSSNFSNNDNFKSVDQITNDLSRIL
Protein: Arpin (H0YL85)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
Sequence:
MSSYKVEAKGDTDRLTPEALKGLVNKPELLALTESLTPDHTVAFWMPESEMEVMELELGAGVRLKTRGDGPFLDSLAKLEAGTVTKCNFTGDGKTGASWTDNIMAQKCSKGAAAEIREQGDGAEDEEWVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLE
Protein: LIMR family protein C622.11 (O94599)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Pre-rRNA-processing protein esf1
- Chromatin assembly factor 1 subunit A
- ATPase histone chaperone abo1
- Histone transcription regulator slm9
- ATP synthase subunit beta, mitochondrial
Sequence:
MSSWFNVGILCLLRFKNVQDNKIIFEAIFEVFLHFLKIPVYMTHLGFPITPTVCLIEMLGLLLLLLIPALFTLIWIYKYIEPHSLISIPGIFVFLGLYVPFVVTLLIPIDVTWDVSLSIWRFLYWLTFVLSWIILPFVQGYMESKFSTPRSRLSDSFYKNLRYYLLLTFLTCVVIAYLRFALRTMSFSNFKELVISLTYFWGLLFVIFLLGNGFVYVPVSMWKKAFITKRAALLERQAVGVYSKLQARLESYSLPSSSISLNNGRNQSSSDFFTSSLTDHAFNPHSSPNGMSNVIALQTTWNQMVKEYNRIMLIKTAKASGSYRLYLPDSYIPIHPVVAYAFYVWILPAFRILFSIFMASMSVIIVVSEVFLHTQYSLVGIILQKFTNSSATSIFVSFLFVYYMRYCTYKSLMRTQFAPHYYYALVPFRATNTASLIYFASQLCRLTLPLCYNFVSLQPYPTQFHQFYGESIDLLPLGNLISKRYPTFILLPIIFSMISLKYRLRQFIYSITLRKSSSASSSDDFDDSSLNSENDDDLFNETSAAYLAEGRALLLGTNNAHV
Protein: Acyl carrier protein 3, chloroplastic (ACP-3) (P25702)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- EMBRYO DEFECTIVE 3147
- NADH dehydrogenase 1 beta subcomplex subunit 9
- Putative acyl-activating enzyme 19
- NADH dehydrogenase 1 alpha subcomplex subunit 6
- Probable NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase iron-sulfur protein 6
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase 1 alpha subcomplex subunit 9
Sequence:
MASIATSASTSLQARPRQLVIGAKQVKSFSYGSRSNLSFNLRQLPTRLTVYCAAKPETVDKVCAVVRKQLSLKEADEITAATKFAALGADSLDTVEIVMGLEEEFGIEMAEEKAQSIATVEQAAALIEELLLEKAK
Protein: Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (Q6I6N2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nuclear factor, erythroid 2-like 2b.
- Nuclear factor, erythroid 2.
- Nuclear factor
Sequence:
MTTTNKANKALKVKREPGENGTSLTDDELVSMSVRELNQHLRGLTKDEILQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKVELDVLRSKYEALQSFARTVARSPVAAARGPITSVIGPLIPGKVAATSVITIVKSKTEARS
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (Q5EAI9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 173
- Protein YIP4a
- Pentatricopeptide repeat-containing protein At5g08510
- Pentatricopeptide repeat-containing protein At5g41170
Sequence:
MGQRNRNVDLEMEQQQSQASLQAEPCILLGSFPQQPDNNNMPAMVAHVPNLEPHSLQDPTYDNSAMFYGLPQYHHHPHQRVPTNFYVPYVAFQAPPGQLPSSSSHGVVGVSPDHEYERNAHFMDHTRGTYKRKNAEGIPGQPQYLSTLAAPFNTPETIAPFGGARNRPGAVTVNTVLPSHAPNNFIQGNYAGHHPFPPPGSMWYDQHHGRSDGSPSFWPTPYMHGSNIFAGSIESSSRNPTSFMYPSQLNPRDHYYSHHHHPAPPPVQGMRGQNATLYPHTASSASYRVPPGSFTPQNTMNSGPLGSEMGSSHMGPVQPTGFRIYQHHQRDDSVPVATLRQHRGGVPRLRVMPDDEVALLEFGDFLGGSGNNHIDHHRDMRLDIEEMSYEELLALSERIGTVNTGLPEEDVKNHLKTRTCSGINFEKESSSPRTKDLETEPCTICQESFKNEEKIATLDCGHEYHAECLEKWLIVKNVCPICKSEALVMEKRKV
Protein: Haloacid dehalogenase-like hydrolase domain-containing protein At2g33255 (EC 3.1.3.-) (Q8RYE9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Haloacid dehalogenase-like hydrolase domain-containing protein At4g39970
- CBBY-like protein
- Catalytic/ hydrolase
- Haloacid dehalogenase-like hydrolase domain-containing protein Sgpp
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- Imidazole glycerol phosphate synthase hisHF, chloroplastic
- Histidinol-phosphate aminotransferase 1, chloroplastic
- Histidinol-phosphate aminotransferase 2, chloroplastic
- Serine--glyoxylate aminotransferase
Sequence:
MTFLLSRTFISLTLRPSCSISMANLTTNAKTRLRGVVFDMDGTLTVPVIDFAAMYRAVLGEDAYKRIKAESPSGIDILHHIESWSPDKQQKAYEIIADYEKQGIDKLQIMPGTAELCGFLDSKKIKRGLITRNVQKAIDIFHQRFEVIFSPALGREFRPYKPNPDPLLHICSTWDIQPNEVMMVGDSLKDDIACGKRAGAFTCLLDETGRYGPDDFSVSGLQPDFKVDSLSKIQNLLETNFDLNP
Protein: DNA-binding response regulator (A0A0H2URZ0)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEKESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVLKERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIADKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL
Protein: 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta (OFOR1) (EC 1.2.7.11) (Q9YA11)
Organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Function: Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate and glyoxylate to form their CoA derivatives.
Interaction partners:
- 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha
- 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha
- Succinate--CoA ligase subunit alpha
- Succinate--CoA ligase subunit beta
- Pyruvate kinase
- Citrate synthase
- 2-oxoacid oxidoreductase
- Pyruvate dehydrogenase complex, E2 component
- isocitrate dehydrogenase
- Acetyl-coenzyme A synthetase
Sequence:
MASRGVASYRTEVWSDWCPGCGDFGILAAMQKAFAELNLDPAQTVVVSGIGCSSKTPHFINVNGVHTIHGRGIAFATGIKLANPQLKVIVNGGDGDLLGIGVAHFVALGRRNLDVTVLIHNNKVYGLTKGQASPTLRRGEKVKSLPVPNLQDAVNPIALAIASGYTFVARAYSLWVDHLKEILKAAINHKGSAVIDVLQPCVTYNDIYTAEFYKDRLYKLEDDPSWDPIVRDPSEDEEKKAAAIKKAEEWGTRIPVGVFYVNPLKDTYEERLAQRNPSYSIDNPPALQPISREDGSPIVGPDEFRKIFKRFIVNVKKL
Protein: Rrp40p homologue (Q95Z14)
Organism: Trypanosoma brucei
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSETNPVVRGAVGVHELAPLCSHVCLPGESVLLLEPTAVVTLGSGLHPLQQDGSDDRKESFEASGEEGSTVVVSEFCGPVLRTAGPNHTQLYKLNGPAARRYMYAARDPVVAIVMKKNASYYSCYTGAASLAVLDALGFDGATKTNKPRLQEGDVVYAFVKGNADASSLDTKFDDGRVVVSSSDEVELSCMAAEVGLVARDWTSAEAVFGPLVGGTVVRVALPYARSLIDGPASRLLALLGDRVPYDVCVGVNGLVWVRGHPSAADPTAAARRTVAVAACVVEAQDAATLEEMEAHVRGYFPKE