wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger protein 786 (Q8N393)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger protein 223
Sequence:
MAEPPRLPLTFEDVAIYFSEQEWQDLEAWQKELYKHVMRSNYETLVSLDDGLPKPELISWIEHGGEPFRKWRESQKSGNIICSSVDMHFDPGFEEQLFWGSQQAMNSGKTKSHFQLDPESQCSFGSFVSFRPDQGITLGSPQRHDARAPPPLACGPSESTLKEGIPGPRNLDLPGLWDVPAWESTQHPWPVCGESCWENNHLVMHQRGHSKDRTRRAWEKFNKRAETQMPWSSPRVQRHFRCGVCGKSFRRKLCLLRHLAAHTGRGPFRNADGEMCFRHELTHPSHRLPQQGEKPAQCTPCGKRSLPVDSTQARRCQHSREGPASWREGRGASSSVHSGQKPGSRLPQEGNSHQEGDTEALQHGAEGPCSCSECGERSPMSARLASPCRAHTGEKPFQCAHCTKRFRLRRLLQVHQHAHGGERPFSCRKCGKGFAKQCKLTEHIRVHSGEKPFRCAKCGRNFRQRGQLLRHQRLHTDEKPFQCPECGLSFRLESMLRAHRLRHGGERPFSCSECGRGFTHQCKLREHLRVHSGERPFQCLKCDKRFRLKGILKAHQHTHSKERPFSCGECGKGFTRQSKLTEHLRVHSGERPFQCPECNRSFRLKGQLLSHQRLHTGERPFQCPECDKRYRVKADMKAHQLLHSGEMPFSCECGKGFVKHSKLIEHIRTHTGEKPFQCPKCDKSFRLKAQLLSHQGLHTGERPFHCPECDKNFRERGHMLRHQRIHRPERPFACGDCGKGFIYKSKLAEHIRVHTKSCPAPNELDIKKRLSQLFAMIEADWS
Protein: Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Protein SEC35) (P53271)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. COG2 is required for ER to Golgi vesicle docking. Not essential for viability.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:9606204}; Peripheral membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:9606204}; Cytoplasmic side {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:9606204}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 7
- Intracellular protein transport protein USO1
- Protein transport protein BET1
- GTP-binding protein YPT1
Sequence:
MDFLNDDELDLDLPVTAEISKELFATEIEKYRESETNGTDVDNFDVDRFLVQKNFHYLPLDSLIRDLSGLSQKMVQTLLEQIRSNYDDYLTFSNTYTDEENETLINLEKTQSDLQKFMTQLDHLIKDDISNTQEIIKDVLEYLKKLDEIYGSLRNHSQLTEALSLGKRLSKSLHEMCGIEPLEEEICSGLIEQLYKLITASRRILESCADSNSPYIHHLRNDYQDLLQEFQISLKILTEKCLENPSSLQNLSLTLVSIIKTA
Protein: Protein GrpE (HSP-70 cofactor) (Q9CGY9)
Organism: Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01151}.
Interaction partners:
Sequence:
MSEETKEEIKNEKVDEEVTEELTEEALEDIVEEEINELDEAQKLATEWENKFLRVSAEMQNVQRRGNEERLQLIKYRSQDLAKKILSSLDNLERALAVEGLTDDVKKGLEMVQESLISALKEEGVEEVSYESFDHNIHMAVQTVPADDEHPADSIVQVFQKGYQLHERLLRPAMVVVAQ
Protein: Hisactophilin-2 (Histidine-rich actin-binding protein 2) (HS II) (P42526)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May act as an intracellular pH sensor that links chemotactic signals to responses in the microfilament system of the cells by nucleating actin polymerization or stabilizing the filaments.
Subcellular location: Cytoplasm. Cell membrane; Lipid-anchor; Cytoplasmic side.
Interaction partners:
- EARP-interacting protein homolog
- Small GTPase
- Probable serine/threonine-protein kinase kinX
Sequence:
MGNRAFKAHNGHYLSAEHDHVKTHHGHHDHHTHFHIENHGSKVALRTHCGKYVSIGDHKQVYLSHHLHGDHSLFHLEHHHGKVSIKGHHHHYISVDGHGHVSTSHHHDHHATFEEHIL
Protein: Ras-related protein Rab-3 (P25228)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity).
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Interaction partners:
- Rab3 interacting molecule, isoform F
- Unc-13, isoform E
- Synaptotagmin 1
- Liprin-alpha, isoform E
- Synapsin
- Synaptobrevin
- Kinesin-like protein unc-104
- MAP kinase-activating death domain protein
- Vesicular glutamate transporter, isoform A
- FI18813p1
Sequence:
MASGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC
Protein: C-type lectin domain-containing protein (Q18821)
Organism: Caenorhabditis elegans
Interaction partners:
- C-type lectin domain-containing protein
- VWFA domain-containing protein
- C-type lectin domain-containing protein
- Cytochrome b561 domain-containing protein
Sequence:
MLRVLFFTLVALLCFVSPNCLPGDTPFEIYCFSYNRVHGTFNDSDAHCLKTVGGSLVSIHSMIENNWIQKLAVDNLDADYDLFWIGGSDEGHTNDWRWTDGSVLNFTNPGPGQPLEDRHCGAMQLSTGRWFSDLCTVKHQFLCQYPNGAYPTGGSYTCPPCPSCSK
Protein: Serine/threonine-protein kinase/endoribonuclease IRE1a (Endoplasmic reticulum-to-nucleus signaling 1-2) (Inositol-requiring protein 1-2) (AtIRE1-2) (Serine/threonine-protein kinase/endoribonuclease IRE1-2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] (Q9C5S2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes. Involved in organ growth regulation. Plays a role in plant immunity and abiotic stress responses.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:11706177}; Single-pass type I membrane protein {ECO:0000269|PubMed:11706177}.
Interaction partners:
- Heat shock 70 kDa protein BIP3
- Heat shock 70 kDa protein BIP1
- bZIP transcription factor 28
- Heat shock 70 kDa protein BIP2
- bZIP transcription factor 60
- bZIP transcription factor 17
- Subtilisin-like protease SBT6.1
- RNA-binding
- DnaJ protein ERDJ3B
- Membrane-bound transcription factor site-2 protease homolog
Sequence:
MPPRCPFLRHLFFLLLLLSPWIMSPCGGAADDVTYPIVPSSPGRRSILQIRREPPTEPNTKLVVDRDGKVFLKQQPKETPYWSFSTGSPMHSLYQAPANNNTENATEITRPHIIVEYLNNSKAATTVDGYHNWTVQEFFRQKPLVTDDGVTLGSETTSAYLVDGRSGRLIHVYKSTGDTKITNALVKPASTEDFVNEPLLIRRTDSKLEHFSKTTGKLVWNLTVSHFRAALLCDPVFNSGYDLGPKLQTGIYMPLLCGSQIDVRGPEIVIRVLHDQPMNVKMLPSPSLNHFESENSIMPFGKARESRKLQEQHKQKYTYLFGQWSPVKLLAPLVLLGVVVSVFIKKFSSRGSDVSLKAGPSKKKKNRKSAKDTNRQSVPRGQDQFELIEGGQMLLGFNNFQSGATDGRKIGKLFLSSKEIAKGSNGTVVFEGIYEGRPVAVKRLVRSHHEVAFKEIQNLIASDQHTNIIRWYGVEYDQDFVYLSLERCTCSLDDLIKSYLEFSMTKVLENNDSTEGVAAYKIQLDSLEGVIKGNNFWKVGGHPSPLMLKLMRDIVCGIVHLHELGIVHRDLKPQNVLISKDMTLSAKLSDMGISKRMSRDMSSLGHLATGSGSSGWQAPEQLLQGRQTRAVDMFSLGCVIFYTITGCKHPFGDDLERDVNIVKNKVDLFLVEHVPEASDLISRLLNPDPDLRPSATEVLLHPMFWNSEMRLSFLRDASDRVELENREADSEILKAMESTAPVAIGGKWDEKLEPVFITNIGRYRRYKYDSIRDLLRVIRNKLNHHRELPPEIQELVGTVPEGFDEYFAVRFPKLLIEVYRVISLHCREEEVFRKYFKCDII
Protein: Ataxin 2 like (H3BUF6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAAPPFLPVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILQSHPSQQLPFHPPGN
Protein: Translocase of chloroplast 90, chloroplastic (AtToc90) (EC 3.6.5.-) (90 kDa chloroplast outer envelope protein) (Plastid protein import 4) (Q6S5G3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000269|PubMed:15284497}; Single-pass membrane protein {ECO:0000269|PubMed:15284497}. Cytoplasm {ECO:0000269|PubMed:15284497}. Note=Cycles between the cytoplasm and chloroplast, probably as a soluble preprotein receptor. The anchoring to the chloroplast outer membrane required the GTPase activity and GDP. May contain beta barrel transmembrane regions (Probable). {ECO:0000305}.
Interaction partners:
- Protein TOC75-3, chloroplastic
- Protein TOC75-4, chloroplastic
- Protein TIC 56, chloroplastic
- Solute carrier family 40 member 3, chloroplastic
- Protein TIC 100
- Outer envelope protein 80, chloroplastic
- Protein TIC110, chloroplastic
- Protein TIC 22, chloroplastic
- Protein TIC 40, chloroplastic
- Chloroplastic import inner membrane translocase subunit TIM22-2
Sequence:
MKGFKDWVFALSNSMASSRPLLGSDPFFRDPHQEQDNHSQAPAAPQPVTLSEPPCSTSSDLEILPPLSQQQVPLESLYQSSIDLNGKKHNPLAKIGGLQVQFLRLVQRFGQSQNNILVSKVLYRVHLAMLIRAEESELKNVKLRQDRAKALAREQESSGIPELDFSLRILVLGKTGVGKSATINSIFGQPKSETDAFRPGTDRIEEVMGTVSGVKVTFIDTPGFHPLSSSSTRKNRKILLSIKRYVKKRPPDVVLYLDRLDMIDMRYSDFSLLQLITEIFGAAIWLNTILVMTHSAATTEGRNGQSVNYESYVGQRMDVVQHYIHQAVSDTKLENPVLLVENHPSCKKNLAGEYVLPNGVVWKPQFMFLCVCTKVLGDVQSLLRFRDSIGLGQPSSTRTASLPHLLSVFLRRRLSSGADETEKEIDKLLNLDLEEEDEYDQLPTIRILGKSRFEKLSKSQKKEYLDELDYRETLYLKKQLKEECRRRRDEKLVEEENLEDTEQRDQAAVPLPDMAGPDSFDSDFPAHRYRCVSAGDQWLVRPVYDPQGWDRDVGFDGINIETAAKINRNLFASATGQVSRDKQRFTIQSETNAAYTRNFREQTFSVAVDLQSSGEDLVYSFQGGTKLQTFKHNTTDVGVGLTSFGGKYYVGGKLEDTLLVGKRVKLTANAGQMRGSGQTANGGSFEACIRGRDYPVRNEQIGLTMTALSFKRELVLNYGLQTQFRPARGTNIDVNINMNNRKMGKINVKLNSSEHWEIALISALTMFKALVRRSKTEMTEENEEEKIVNFLVS
Protein: Regulator of G-protein signaling 4 (Regulator of G-protein signalling 4) (Q6TEM0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MCKGLAALPATCLKSAKDIKHKIGFLLQKPDPPQEQKALKEKEKEKDKEKVKDTVVNRITPAETEKWKTSFTNLIKNDDGRKAFASFLQSEYSQENIEFWVACEDFKQTPADKMNLKARNIFERYIEADSPREVNLDSVTREQTRKNLEMCDVSCFDEAQSKIFTLMEKDSYRRFLRSRLFLELSQPAMDNKPCGLEKKVKRQISDYSQCLPSYA
Protein: Putative response-regulator ArmR (Response regulator) (Q8GQ91)
Organism: Pseudomonas aeruginosa
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MRILLVEDDKLIGRGIVAGLHKHGIAVHHVGTAEEAEATHAEDTFHALVLDLGLPDRDGMELLASMRAVEPQLPVLILTARDAIEHRLKGLHEGADDYMIKPFDLRELAARLHALVRRTQGRAAQVISAGPLRLEPESGLAWFQGEPVSLSRREVDLLAHLANADGRWVPPDMLNERLYGLGEEIGSNALNVHIHNIRRKLGAEAIETVRGLGYRLGWRLAS
Protein: Sodium channel regulatory subunit beta-3 (Q9NY72)
Organism: Homo sapiens (Human)
Function: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:24567321}; Single-pass type I membrane protein {ECO:0000305|PubMed:35301303}.
Interaction partners:
- Sodium channel regulatory subunit beta-2
- Sodium channel regulatory subunit beta-4
- Sodium channel protein type 7 subunit alpha
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 2 subunit alpha
- Sodium channel protein type 4 subunit alpha
- Glycerol-3-phosphate dehydrogenase 1-like protein
- Sodium channel protein type 10 subunit alpha
- Potassium voltage-gated channel subfamily E member 3
- Transient receptor potential cation channel subfamily M member 4
Sequence:
MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE
Protein: Mitochondrial thiamine diphosphate carrier 2 (Q9FI73)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitochondrial transporter that mediates uptake of thiamine diphosphate (ThDP) into mitochondria.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:22426856}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Nudix hydrolase 24, chloroplastic
- Thiamine pyrophosphokinase 2
- Thiamine pyrophosphokinase 1
- Hydroxyethylthiazole kinase
- Nudix hydrolase 20, chloroplastic
- Purine-uracil permease NCS1
- 5-formyltetrahydrofolate cyclo-ligase-like protein COG0212
- Bifunctional TH2 protein, mitochondrial
- Bifunctional TENA-E protein
- ACT domain-containing protein ACR1
Sequence:
MIPTTATVDDEPGQIKRALIDASAGAISGGVSRSVTSPLDVIKIRFQVQLEPTTSWGLVRGNLSGASKYTGMVQATKDIFREEGFRGFWRGNVPALLMVMPYTSIQFTVLHKLKSFASGSTKTEDHIHLSPYLSFVSGALAGCAATLGSYPFDLLRTILASQGEPKVYPTMRSAFVDIIQSRGIRGLYNGLTPTLVEIVPYAGLQFGTYDMFKRWMMDWNRYKLSSKIPINVDTNLSSFQLFICGLGAGTSAKLVCHPLDVVKKRFQIEGLQRHPRYGARVERRAYRNMLDGLRQIMISEGWHGLYKGIVPSTVKAAPAGAVTFVAYEFTSDWLESISW
Protein: Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Nucleoporin Nup93) (Q66HC5)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:15703211}; Peripheral membrane protein {ECO:0000269|PubMed:15703211}. Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q8N1F7}. Nucleus envelope {ECO:0000250|UniProtKB:Q8N1F7}. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore. {ECO:0000250}.
Interaction partners:
- Nuclear pore complex protein Nup155
- Nucleoporin 205
- Nuclear pore complex protein Nup98-Nup96
- Nucleoporin NUP188
- Nuclear pore complex protein Nup107
- Nucleoporin NUP35
- Nuclear pore complex protein Nup54
- E3 SUMO-protein ligase RanBP2
- Nuclear pore complex protein Nup85
- Nuclear pore complex protein Nup153
Sequence:
MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYVSDVSPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCASVAELDDKSISDMWAMVKQMTDVVLTPATDALKSRSSVEVRMDFVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESMEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSATRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN
Protein: Structural maintenance of chromosomes protein 5 (Q9VP12)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAGDRALSSKQLAGRIHSVYCKDFVSYSEITFHPKHYLNVLTGPNGSGKSTIVSAIILGLGGEPILLDRSASVADYIQSNKTSATIIVRVYGRTPNTTETFRRIINSNGLSTFSVNDKDTSKKNFLAAVSSFNIQVSNLCQFLPQDRVQDFSKMNPQELLLNTMSSVCDEDLINSFNSLKQMRTEQANVHANREKEKSDLVKKQKRLEHLQMTVSQYKEREEVKQKLQVYSAKKLWVETQAGEAKAAEMKTQVKNAKTQSDKLKNQHDKLLQSQEQIEKEKESLRKALLEKQNIKKSRRTATECDNLNQLVENKIYELETLNKSRPLIVSELERAKESCAAARGKAMEQYSRRRQLEQKLNDEMIPEITAYKLKIERLRNVKMQKIDEIRAKNPNLVVAMNWLAQNKQRYKLNVYDPMILELTVQNHEDAKFLENVVAQRDLFAFACEDKGDMSDLINELCVKQKLGVNVIYCAPSDRLVYSPKTPIDDLRSFGFRSYLVDLVTGPIPLINKLCASYSIHNIPIGTEAVGNYTSSIPKAIRVYFGGSKKFVVTASRYRSDTILTESSIRAKNQLITVDSQQLALVMKQCSEAVKESDSIKNAITQTDNEFERLQAVAKDEQEKRRKLDQKIAHFNSLKTEIETLQKKLEALRNSDSLDCLETNFCNSLHKDLKKIFDADAELCSCLKAIDRLIIEKNMAQTKVSIYMLQHETQIEALKESEEQSKAATRDFQQLLQCLENQISDVNKRKSAIQGLCHGEIPTSSKFPFKKEFRELENIDLPELREAIHDFQARLECMKSVNSEAISSYQGLQNEVKQLEEGIQESVNQAKSIESGMSNLYDKWEPKLNSLVETISTKFSEFMESIEYVGEVVLSKTDKIMVQFRRGLQLQPLDKFIQSGGERAVSIAIYSLSLQHVTHVPFRCVDEINQGMDATNERHIFDLLLKEATKHGSAQYLFVTPKLLRDLNYNEHLCVSIVHNSKTVCHGMQFPMA
Protein: Fibroblast growth factor (FGF) (G1NDN4)
Organism: Meleagris gallopavo (Wild turkey)
Interaction partners:
Sequence:
ADTLGCTGLPTEGVGTAQCHRFWERITNGGFFLRINPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVSANRFLAMKEDGRLLALKCATEECFFFERLESNNYNTYRSRKYSDWYVALKRTGQYKPGPKTGPGQKAILFLPMSAKS
Protein: Nucleoside diphosphate kinase (EC 2.7.4.6) (Q9IAD3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection {ECO:0000256|ARBA:ARBA00004316}.
Interaction partners:
Sequence:
MSAKTERTFIAAKPDGVQRGLMGEIIKRFEQKGFRLVAMKFLQASEDLLKQHYIDLKDRPFYPGLVKYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIEVGRNIIHGSDSVDSANTEISLWFKPEELVSFKSCAQQWIYE
Protein: Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) (P0C6S7)
Organism: Rattus norvegicus (Rat)
Function: Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells.
Subcellular location: Cytoplasm {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 3]: Postsynaptic density. Cell projection, dendritic spine. Nucleus. Nucleus, Cajal body. Note=The synaptic localization requires DLG4 interaction. Translocation to the nucleus in response to stimulation of NMDA receptors (NMDARs) in a calcium-independent manner.
Interaction partners:
- Ras/Rap GTPase-activating protein SynGAP
Sequence:
MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQFEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHPSQKSLQIATLLQDYLEGVGRSVVLEEEHAQEDTAQETRLSSPAQSPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHTISDHYLDNLSKISEEELGKNGSQSVRTSSTINLSPGEVEDEEEDPNSCGPTGLWEALTPCNGCRNLGFPMLAQESYPKKRNYPMEIVPSASLDTFPSENENFLCELVDTAVTKKPCSLEIARAPSPRTDNASEVAITAPGTGHHRNSSTGPTPDCSPPSPDTALKNIVKVIRPQPKQRTSIVSSLDFQRMNHNQEYFEISTSTGCTSFTSSPPVSPPTSSVETTEIKNEGAEHTDDLSQQEDDEPPKEYDAGQFAGLLHGSSPACEAPENPFHLYGKRNQGEDGQEEASLANSPLPFKQTPIENNPEPSVKKIKPKVVSRTIFHKRSHQLENHTIVGTRMSRGGSRNGDQWGVNPGGFVERACTLGRIRSLPKALIDMHLSKNVSKSDSDLIAYPSKDKARVNWSKSSTAERSSKDNSERTPSFTSEWEEIDKIMNSIDVGINSELEGMNGEATRPRCPVQTVGQWLESIGLPQYENHLTANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWELELINVLKISLIGHRKRILASLGDRLHEDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDAANKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQIDPSEQKTLANLPWIVEPGQEAKRGINTKYETTIF
Protein: Polyprotein of EF-Ts, chloroplastic (150 kDa pro-protein) (Protein EMBRYO DEFECTIVE 2726) [Cleaved into: Plastid-specific ribosomal protein-7, chloroplastic; Elongation factor Ts, chloroplastic (EF-Ts)] (Q9SZD6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP (By similarity). It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:16980539, ECO:0000269|PubMed:21139083}.
Interaction partners:
- Elongation factor Tu, chloroplastic
- Elongation factor Tu
- Ribosome-recycling factor, chloroplastic
- Ribosome-recycling factor, chloroplastic
- Trigger factor-like protein TIG, Chloroplastic
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Translation initiation factor IF3-1, mitochondrial
- Small ribosomal subunit protein uS9c
- Small ribosomal subunit protein bS1c
- Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain-containing protein
Sequence:
MATITPSSISNAWLIPGASFTVKKSDCSIKCSFSRKAGKQILSSTQRLVLPLSTSLRLFPTHGRQFVLHPHRRATGTDVVAAVEEQDSTPVVAEDKETVASEKSDAPAPTSQSRGTARPGRKSEMPAVKNEELVPGATFTGKVRAIQPFGAFVDFGAFTDGLVHVSQLSDNFVKDVSSVVTIGQEVKVRLVEADIESKRISLTMRENDDPPKRQSGGSDKPRSGGKRDGSKGGGQRKGEGFNSKFAKGQMLDGVVKNLTRSGAFITIGEGEEGFLPTAEEADDGIGSMMMGGSSLQAGQEVKVRVLRIARGRVTLTMKEEDDGKFDETTTQGVVHTATNPFMLAFRKNEEIAAFLDKREEEAEKPPVETPVEPEAEASVTSAEVEESVCVPAEVTSEEVPSSETPKVVEEEVIATKAEDDSPEKEEQTETLAAAAEAEEVVPPIPETKSEEEIVENSIPPNSATDEVSSPEALASEEVEKEQVVAETPVDEVKTPAPVVTEASSEESGNTATAESIKGISPALVKQLREETGAGMMDCKNALSESEGDMVKAQEYLRKKGLASADKKASRATSEGRIGAYIHDSRIGVLLEVNCETDFVSRGDIFKELVDDLAMQVAACPQVEYLVTEDVSEEIVKKEKEIEMQKEDLLSKPEQIREKIVDGRIKKRLDSLALLEQPYIKDDKVIVKDLVKQRIATIGENIKVKRFVRYTLGEGLEKKSQDFAAEVAAQTAAKPKAKEEPKAEEAKEAVASPPTTVVSAALVKQLREETGAGMMDCKKALAATGGDLEKAQEFLRKKGLSSADKKSSRLASEGRIGSYIHDSRIGVLIEVNCETDFVGRSEKFKELVDDLAMQAVANPQVQYVSIEDIPEEIKQKEKEIEMQREDLLSKPENIREKIVEGRISKRLGEWALLEQPYIKDDSVLVKDLVKQTVATLGENIKVRRFVKFTLGEDN
Protein: GPI mannosyltransferase 2 subunit PGA1 (Processing of GAS1 and ALP protein 1) (P53896)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential component of the GPI mannosyltransferase 2 complex. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17615295}; Single-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17615295}.
Interaction partners:
- GPI mannosyltransferase 2
- Probable alpha-1,6-mannosyltransferase MNN11
- Dolichyl-phosphate-mannose--protein mannosyltransferase 5
- Dolichyl-phosphate-mannose--protein mannosyltransferase 2
- Dolichyl-phosphate-mannose--protein mannosyltransferase 1
- Dolichyl-phosphate-mannose--protein mannosyltransferase 4
- Mannan polymerase I complex VAN1 subunit
- Putative glycosyltransferase HOC1
- Mannan polymerase complexes subunit MNN9
- Probable alpha-1,6-mannosyltransferase MNN10
Sequence:
MVRPQNVHWFIATIVFFIGFVHANTESILYKVPHNFPLKKPRDSSTYARDVNLISSISLSGEAMSQITIEANTTDLELHNTTYIELADLQRDETYQIKVCWSAIHPISINNLQTITIPRFTEFQGTKSDYARILVTFQVLSDSYPSEHAMVPIQVSLITTRLGIPVDIYPTLIVMVLLVAGLVVTRAPHVLNDLLLKF