wanglab/gogpt-training-data huggingface dataset:
Protein: Autophagy-related protein 9 (Q9TXN6)
Organism: Caenorhabditis elegans
Subcellular location: Preautophagosomal structure membrane {ECO:0000256|ARBA:ARBA00004511, ECO:0000256|RuleBase:RU364027}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004511, ECO:0000256|RuleBase:RU364027}.
Interaction partners:
- Autophagy-related protein 18
- Autophagy-related protein 2
- Autophagy-related protein 13 homolog
- Serine/threonine-protein kinase unc-51
- Ubiquitin-like protein atg-12
- Ubiquitin-like modifier-activating enzyme ATG7
- Autophagy-related protein 5
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Beclin homolog
- non-specific serine/threonine protein kinase
Sequence:
MFNSQSKRAYQQIDDDFDDEVLRNSTCTSRFMQGWGSSTRSLLFGGASNDEQRNLIASSSSHHSYHDSPAEEPPETHYEQFTATHNHGPPTMASSSQLNSRRWDHVLNLDEFFTHIYEYHQNGGYLCIVLQKVFSLLQFIFVMSFTTFFTQCVNYQFLFANTNVTSHGTVNQGKRHFGDAVVDNCPAHISIWMIFAILAAIVYWITRVIKHAQYIMKMSEIQQFYAHELKIADDQLPNLTWHAIVKRICEAQKKLRLSIHQDNITSIYIYHRILRYKNYMTGMINKRILHPVFDVPFLGPIAYLPNNLKHEIERILFTSSTSAWTNGPNLREEYKHHEQLDMAAKKMKEDCKFYGFLSLVLMPLLLPFQIMESFFSLTELIKRRPDGLGMRRYSNFGRYLLRHFNELDHELSARLNRSHIYAAAYMDQFFSPVLEIAAKNITFIAAAVFGVLTILSAWDEDVLQVEHVITVLTICGIVVLVCRGMIPDENLVWQPEILMTHVTSELHYLPSTWKGKAHTTGVRHEFDQLFQMKWMFFVLELTSPIFTPFVLLFWLRPRCSQLANFFHDYTERVDGLGDVCSFAVMDVGKHGDPKWNHIKELKAIVEDQEDQQQAQSVVTSLNRARDGKTELSILHFKTTNPEWQPPKASEKFLRKFRNRLGQEASMLAPLTSMHLGQQMDRQQQQDQILPPRNILLESVHSIVPTTSGGISASQVAPGRHPLIGDGLHRIDGPVGNAFQGIQGAKLGSGGVLASLYQEQPRAAESLSNSLRASGVDIDGAGAEMRINALFLRGLHDESIIHSSSRNYGGTTSSFNMHPTAMQSVFAMPDGFGQPAPAVESSLIDIETPTYHRESVQRSAAEHKMEHETPEPLAELPDLPGPSSSEHQQRSRLVPNTQHRQINEEEEEEEEEDNTPPLSFSS
Protein: Insertion element IS6110 uncharacterized 12.0 kDa protein (P9WKH5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Putative transposase for insertion sequence element IS986/IS6110
Sequence:
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR
Protein: Putative ABC transporter, permease protein (Q60CD4)
Organism: Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Interaction partners:
- ABC transporter, ATP-binding protein
- Mce family protein
- ABC transporter, ATP-binding family protein
- Mce/MlaD domain-containing protein
- Putative lipoprotein
- Intermembrane phospholipid transport system permease protein MlaE
- Toluene tolerance protein
- STAS domain protein
- Toluene tolerance protein
- Putative ABC-transporter permease protein
Sequence:
MRSMIVQVRHPEKRPRPFRQARRNMLASQSSAETSALPPLSPPEFAVEDGTAVVHGHWNLRGLIAASPDLRERLCRAARRPDLEWDLRGVNVLDSAGAFVLWQAWGERLPERIALRHEQQSAFRRWQTGGIPAVRDGRRPPVPIRRRIIAAIAGLGSHLLAVLALLGQLILDLAHLARHPADIPWREISATIHETGGRALGITALVGFLIGVVVSYLSSLQLKTFGAQVYIVNILGMSIIRELGPLLAAILVAGRSGSSMTARIGVMRVTQELDALAAMGISQSLRLILPKVVALVVALPLLVVWTDVVALAGGAVSAHLELEIGYHQFFQKLPSAVPVANFAIGLGKAAVFGLFVALIACHYGLRIAPNTESLGNETTNSVVVSITLVILVDAVFAILFRSVGIR
Protein: Kinesin-like protein cut7 (Cell untimely torn protein 7) (P24339)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Could be a spindle pole body motor. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules which interdigitate to form a short spindle that elongates to span the nucleus at metaphase. Mutations at cut7 block spindle formation.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Interaction partners:
- Tubulin beta chain
- Tubulin alpha-1 chain
- Anaphase spindle elongation protein 1
- Tubulin alpha-2 chain
- Kinesin-like protein 1
- Kinesin-like protein 2
- Mitotic spindle checkpoint component mad2
- Separin
- Aurora kinase
- Uncharacterized WD repeat-containing protein C32H8.09
Sequence:
MAPRVAPGGSQQFLGKQGLKAKNPVSTPNSHFRSASNPRKRREPPTIDTGYPDRSDTNSPTDHALHDENETNINVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSMLVTKTYAFDKVFGPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGLIPRALYQLFSSLDNSNQEYAVKCSYYELYNEEIRDLLVSEELRKPARVFEDTSRRGNVVITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTDETNSLTINNNSDDLLRASKLHMVDLAGSENIGRSGAENKRARETGMINQSLLTLGRVINALVEKAHHIPYRESKLTRLLQDSLGGKTKTSMIVTVSSTNTNLEETISTLEYAARAKSIRNKPQNNQLVFRKVLIKDLVLDIERLKNDLNATRKKNGVYLAESTYKELMDRVQNKDLLCQEQARKLEVLDLNVKSSREQLQYVSKSNQEHKKEVEALQLQLVNSSTELESVKSENEKLKNELVLEIEKRKKYETNEAKITTVATDLSQYYRESKEYIASLYEKLDRTERNNKENENNFWNLKFNLLTMLRSFHGSFTDETNGYFTLLNDFNASMEELLNTHSNQLLISMTKITEHFQSLDEALQSARSSCAVPNSSLDLIVSELKDSKNSLLDALEHSLQDISMSSQKLGNGISSELIELQKDMKESYRQLVQELRSLYNLQHTHEESQKELMYGVRNDIDALVKTCTTSLNDADIILSDYISDQKSKFESKQQDLIANIGKIVSNFLQEQNESLYTKADILHSHLNDTNSNIRKANEIMNNRSEEFLRNAASQAEIVGANKERIQKTVENGSQLLDSKSKAIHSNSRSMYDHCLALAESQKQGVNLEVQTLDRLLQKVKEHSEDNTKEKHQQLLDLLESLVGNNDNLIDSIKTPHTELQKITDHVLKGTTSLANHTNELLGLGDESLCNLETTIEDTSLVKLETTGDTPSKRELPATPSWTRDSSLIKETTNLNLDSDKKFVRETYTSSNQTNEPDVYDKPSNSSRTSLLRSSRSAYSKMKR
Protein: Basic phospholipase A2 A (svPLA2) (EC 3.1.1.4) (Crotoxin basic chain 1) (Phosphatidylcholine 2-acylhydrolase) (P86169)
Organism: Crotalus durissus ruruima (South American rattlesnake) (Mt. Roraima rattlesnake)
Function: Snake venom phospholipase A that has strong antimicrobial activity against the Gram-negative bacterium X.axonopodis. Antimicrobial activity is not abolished by EDTA or p-BPB and is therefore not strongly dependent on the enzymatic activity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Subcellular location: Secreted {ECO:0000269|PubMed:19013478}.
Interaction partners:
Sequence:
HLLQFNKMIKFETRKNAIPFYAFYGCYCGWGGRGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYPYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKYGYMFYPDSRCRGPSETC
Protein: Lipolysis-activating peptide 1-alpha chain (BotLVP1-alpha) (LVP1-alpha) [Cleaved into: Neurotoxin BmKBTx-like] (P84810)
Organism: Buthus occitanus tunetanus (Common European scorpion) (Buthus tunetanus)
Function: The heterodimer non-edited LVP1 induces lipolysis in rat adipocytes. Induction of lipolysis by LVP1 appears to be mediated through the beta-2 adrenergic receptor pathway (ADRB2). Intracerebroventricular injection is not toxic to mice.
Subcellular location: Secreted {ECO:0000269|PubMed:15680238}.
Interaction partners:
Sequence:
MMKLVLFGIIVILFSLIGSIHGISGNYPLNPYGGYYYCTILGENEYCKKICRIHGVRYGYCYDSACWCETLKDEDVSVWNAVKKHCKNPYL
Protein: Uncharacterized protein (Q38BX5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- 40S ribosomal protein S13, putative
- U3 small nucleolar RNA-associated protein 6 N-terminal domain-containing protein
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- KRR1 small subunit processome component
- U3 small nuclear ribonucleoprotein
- Bms1-type G domain-containing protein
- Uncharacterized protein
- BING4 C-terminal domain-containing protein
- AATF leucine zipper-containing domain-containing protein
- U3 small nucleolar RNA-associated protein 18
Sequence:
MLAKKRAERQHAITATAGGERKKELQKLKRRREESNEEAKRDGRSSERKHRLSGSERLSEDPMLLSAEDPTSVLRAIGDHVNTRLKELDFDDDIDADLFDERQRQLREEAELAAGTRSRLLASHIAEFLHKQQKKGTIESEKVESPSATDVSAVFVAHNSNAVTAVCSLGNEIVFLGDKTGAVYFVELRDNAGSTRKELLSPCLSAAVLSIAVSDTRGVRPSQRTLFERTTADVSVTSYVAVGAADGTIGIWVTDTRRHLGTLTMHRSAVTGLAFRNDTLYSGGYDEALRVWALPQMSCEDKLFGHTGRVFGLHCLRRERCATVGDDGTMRFWKVDAATQQEFTASAHFGGKVVLECVVMMNDFIVLCGAANGALLVFDVGKRKPVAVREGAHGYGFVGDGTGLESEAIAMRQKLDGSVVSETRIPNPITAVAAIPYSDTAASASYDGVVRLWRVGAASESSGKTGTGSGVPATPVVQPSSLDCLASIPVRAIVTSLYFPPTSDVLLIACSKEPRLGRWVVQRSALNSVYVVPLNQETRFKLSSRGRVEHLPTLLYGIDNDGASDEADRMEDATEGLSDAGGRGGSYRSHDEVGNGGEEGDDGTETDNSTGMFTVGEEGQMKFSMPMSNGDRYHGTKKKSKKRTPGAKGEVCAPKTSSKRSSTEAAEEERRKRKKKKDKKKGAGGGKHSTAGEEDK
Protein: Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (Selenoprotein O) (SelO) (Q08968)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Tyr residues of target mitochondrial proteins (AMPylation). Involved in redox homeostasis by regulating the cellular response to oxidative stress. Regulates protein S-glutathionylation levels possibly by AMPylation of deglutathionylation enzymes such as glutaredoxins.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:30270044}.
Interaction partners:
- Putative uncharacterized protein YPL222C-A
- Probable oxidoreductase AIM17
Sequence:
MGEKRTIIKALKNSAASHFIKKLTADTSLSSIQEAINVVQQYNATDPVRLKLFHTPRMVSQGAHFAFCLPTKKPHYKPLLLSQNALDEFNLVQDQDLEKILSGEKVYYSDSIFPYSTVYSGFQFGSFAAQLGDGRVVNLFDLKDKCSGQWQTFQLKGAGMTPFSRFADGKAVLRSSIREFIMSEALHSIGIPSTRAMQLTLLPGTKAQRRNQEPCAVVCRFAPSWIRLGNFNLFRWRHDLKGLIQLSDYCIEELFAGGTQFEGKPDFNIFKRDFFPDTETKIDEQVEKDETEVSTMTGDNISTLSKYDEFFRHVVSLNANTVAHWQAYGFANGVLNTDNTSIMGLTIDYGPFAFLDKFEPSFTPNHDDTAKRYSFANQPSIIWWNLQQFAKDLACLLGPEARDLELLLKGELNSVDDALEKTMIERVQKLVELSANEYKYVFTTRYAQIMSQRLGVDLDLEKCMSSTNLKDIEHAAEKAKEFCDVIVEPLLDILQATKVDYNNFFIHLQNYKGPFFIKDKSDTATLFGAFDEEYLGMFFNSKQLQQMAETEEAFAAGEKVFDANGELRLLNEKLQEIRNWTQDYLTLVPPTETAARASLAKKANPLFVPRSWVLEEVVDDLMYSQRDGLQDPSSELDTSALKKLYLMSVNPYDRTKWDVTLRPELETKWADLSHQDDAKFMMQASCSS
Protein: Cell cycle and apoptosis regulator 2 (H0YB24)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQTVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPAPSN
Protein: Flavin-dependent monooxygenase, reductase subunit HsaB (EC 1.5.1.36) (3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4-hydroxylase, reductase subunit) (Flavin:NADH reductase) (P9WND9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit.
Interaction partners:
- Flavin-dependent monooxygenase, oxygenase subunit HsaA-triene-9,17-dione 4-hydroxylase, oxygenase subunit)-triene-9,17-dione monooxygenase)
- Iron-dependent extradiol dioxygenase
- 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1
- 3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component
- Arylamine N-acetyltransferase
- 3-oxosteroid 1-dehydrogenase
- Secreted protein
- Arylamine N-acetyltransferase
Sequence:
MSAQIDPRTFRSVLGQFCTGITVITTVHDDVPVGFACQSFAALSLEPPLVLFCPTKVSRSWQAIEASGRFCVNVLTEKQKDVSARFGSKEPDKFAGIDWRPSELGSPIIEGSLAYIDCTVASVHDGGDHFVVFGAVESLSEVPAVKPRPLLFYRGDYTGIEPEKTTPAHWRDDLEAFLITTTQDTWL
Protein: Metallo-beta-lactamase L1 type 3 (EC 3.5.2.6) (B3 metallo-beta-lactamase) (Beta-lactamase type III) (Metallo-beta-lactamase L1 type III) (Penicillinase) (P52700)
Organism: Stenotrophomonas maltophilia (Pseudomonas maltophilia) (Xanthomonas maltophilia)
Function: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
Subcellular location: Periplasm {ECO:0000305}.
Interaction partners:
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
Protein: Armadillo repeat containing 10 (H7C2M7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004572}.
Interaction partners:
Sequence:
RELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTKVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI
Protein: Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3) (TGFR-3) (Betaglycan) (Transforming growth factor beta receptor III) (TGF-beta receptor type III) (O88393)
Organism: Mus musculus (Mouse)
Function: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P26342}; Single-pass type I membrane protein {ECO:0000255}. Secreted {ECO:0000250|UniProtKB:P26342}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P26342}. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. {ECO:0000250|UniProtKB:P26342}.
Interaction partners:
- Transforming growth factor beta-2 proprotein
- Transforming growth factor beta-1 proprotein
- Transforming growth factor beta-3 proprotein
- TGF-beta receptor type-1
- TGF-beta receptor type-2
- Activin receptor type-2A
- Inhibin alpha chain
- Bone morphogenetic protein 4
- Activin receptor type-1
Sequence:
MAVTSHHMVPVFVLMSACLATAGPEPSTRCELSPISASHPVQALMESFTVLSGCASRGTTGLPREVHILNLRSTDQGLGQPQREVTLHLNPIASVHTHHKPVVFLLNSPQPLVWHVKTERLAAGVPRLFLVSEGSVVQFSSGNFSLTAETEERSFPQENEHLLHWAQKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLASQPHEKEVHIIELISPNSNPYSTFQVDIIIDIRPAREDPEVVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPDSIGFGKESERSMTVTKLVRNDYPSTQENLMKWALDNGYSPVTSYTIAPVANRFHLRLENNEEMRDEEVHTIPPELRILLGPDHLPALDSPPFQGEIPNGGFPFPFPDIPRRGWKEGEDRIPRPKEPIIPRVQLLPDHREPEEVQGGVNIALSVKCDNEKMVVAVDKDSFQTNGYSGMELTLLDPSCKAKMNGTHFVLESPLNGCGTRHRRSAPDGVVYYNSIVVQAPSPGDSSGWPDGYEDLESGDNGFPGDTDEGETAPLSRAGVVVFNCSLRQLRSPSGFQDQLDGNATFNMELYNTDLFLVPSPGVFSVAENEHVYVEVSVTKADQDLGFAIQTCFISPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEVDKKRFSFVFKSVFNTSLLFLHCELTLCSRNKGSQKLPKCVTPDDACTSLDATMIWTMMQNKKTFTKPLAVVLQVDYKENVPNMKESSPVPPPPQIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETARRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA
Protein: Probable transcription factor RL9 (Protein ROLLED LEAF 9) (Protein SHALLOT-LIKE 1) (Q0J235)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor that regulates abaxial identity during leaf development. Modulates leaf rolling by regulating the programmed cell death (PCD) of abaxial mesophyll and sclerenchyma cells during leaf development.
Subcellular location: Nucleus {ECO:0000269|PubMed:18594992}.
Interaction partners:
Sequence:
MAMVRELELMTSWSNSMGRHRYPTRILVDSFGHKCSASDKGVWTSCSIRAPLQGRGSFRRGANIRFGSLPSSAAVATSGGGRGGGGVVVGGGGGDPWRRLDGSTASTELSLSPPPAQAAGGGGGGGGADALPWRHRPSPPSSAVATTSAAAAAALMAPMMLQPLDAGGGASAPPPPIRGIPIYNGPGGFPFLQPSPTAGDVGHHHHHHPKMGFYSSYHHPSTWPSTSPSPLAAPPGAASSPLDPTAAFLSSPHHRMLSAASGRLNGMLSVSDTLRSYGVPGAAAPGVIGGAHHHHHHLHGGQPFVGALASRFMPKLPAKRSMRAPRMRWTSTLHARFVHAVELLGGHERATPKSVLELMDVKDLTLAHVKSHLQMYRTVKSTDKPAASSGPADGGSGDEEFAGGGQAASGGGDSMCLRGGGGGGVAAAAFAEHGRSASEGAASSVGGGGGGDMDQSSAGNTSTTRWSNSSRDPWLSSNSCNMDAHRSVGLSSPIENLEPCRSSSSQVSNHELSSPSLEFTLGRPDWHGADHD
Protein: cDNA FLJ57184, highly similar to Bromodomain and WD repeat domain-containing protein 2 (Q659C9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
Protein: Mitochondrial morphogenesis protein SLD7 (Synthetic lethality with DPB11-24 mutation protein 7) (Q08457)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the proper function of SLD3 at the initiation of DNA replication. Binds to SLD3 and reduces its affinity for CDC45, a component of the replication fork. Required for mitochondrial morphology.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Cell division control protein 45
- DNA replication regulator SLD2
- DNA replication regulator DPB11
- DNA replication regulator SLD3
- Cell division control protein 6
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM6
- Minichromosome maintenance protein 5
- DNA replication complex GINS protein SLD5
- DNA replication complex GINS protein PSF3
Sequence:
MSRKLCTLNFTLSGKQGSLVIRDIQLWSNRPTASKSTSELRGQFIQYVDLAKLPLWVRSTNMNTYRCYSTSATAQAYFKSKLRNANRGIVIELFDKVDQRSQEPAYLIIFRENTELNCFQVDLTMKHEFDGQVTKLKQDIGKTRASVSKEGSIDIIIQQSQQRKIGTKTEVYRNVHINDKRLQFNETLSKLILGGLRLRGISNSITDYQKLYKITFDAAEFTHRDELKRISMGSGEEVSFESLQETVETLLKLFTKS
Protein: LP04011p (Q8MRH2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALLESTKSLSPSWWASKDRLIRFWPRPLNWARSTQMPRSTLKSNVMRQWRHGRI
Protein: Tubulin beta chain (Q6P5M9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Tubulin alpha chain
- Gap junction alpha-1 protein
- Gap junction protein
- Tubulin alpha chain
- Tubulin beta chain
- Tubulin alpha chain
- Tubulin alpha chain
- Tubulin alpha chain
- Tubulin alpha chain
- Tubulin alpha chain
Sequence:
MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLDRINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEGEEELA
Protein: RNA-binding protein, putative (Q388M7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA-binding protein, putative
- RNA-binding protein, putative
- Pre-mRNA splicing factor, putative
- Pre-mRNA-splicing factor SLU7
- Splicing factor TSR1
- DNA-directed RNA polymerase subunit beta
- U2 splicing auxiliary factor, putative
- Heterogeneous nuclear ribonucleoprotein H/F, putative
- RNA-binding protein, putative
- RNA-binding protein RBP14, putative
Sequence:
MAHVGQQRFGCYIGNIDRSVTLEVLRQVFSQCGTIVDCSLNGRDEDPYRYGFIDFATEDDRARAMKYNGFTLAGRKIKVGISKGNVGRPEGYNNNPTPAPAASNTASSAGQHPQVPSQPQVPAVSVPASFLPGMVQQQQQQGATLLLQLLQQGAIDVNNLTAEQQQVLMASLLPQAPAAAPGMHVMPPTAPMAYVPPPPQQPWGAPRGVYAGGPLGRPAPYTRPPANPQPPEETLKLREVQRKQFLDVVRRDAEKYERKLAERNLKEGRTGSISGSEESSSDEEGEKGHRHSRRKIEGGEDTEPEKSATLPMKTESDSVSCPMEVNCNNEGANISGEEAASNGNGGESNNNEDGDAIDCSNVETEENNVDEEVENKC
Protein: Ferritin heavy chain (EC 1.16.3.1) (Q7KRU8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:17603097}. Secreted {ECO:0000269|PubMed:11804801, ECO:0000269|PubMed:26192321}.
Interaction partners:
Sequence:
MVKLIASLLLLAVVAQAYGDFKCSLAVPEITKDWVDMKDACIKGMRNQIQEEINASYQYLAMGAYFSRDTVNRPGFAEHFFKAAKEEREHGSKLVEYLSMRGQLTEGVSDLINVPTVAKQEWTDGAAALSDALDLEIKVTKSIRKLIQTCENKPYNHYHLVDYLTGVYLEEQLHGQRELAGKLTTLKKMMDTNGELGEFLFDKTL
Protein: RNA pseudouridine synthase 4, mitochondrial (EC 5.4.99.-) (RNA pseudouridylate synthase 4) (RNA-uridine isomerase 4) (Q9LT72)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Protein Iojap-related
- Pseudouridine synthase family protein
- At4g38020 family protein)
- Short integuments 2, mitochondrial
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein uL24c
- Large ribosomal subunit protein mL43
Sequence:
MAKWRLATATLRRQLQSSSPTISTFKNPTKALSAAAHQSTRSYSTTQTDDSRGKWLTLPPFSPTIDGTAVGKDLLSDGDSVKSSTDNSKTTALRWILRCRPDLPRTLVQKLFRLRQVRREMSMSVDGDELQRSQLKRVAAKESLNVGDRIYLPLSVDNDTPQTPPAKKESFQCSDEERKFVCSLVLYKDPAIIVLNKPHGLAVQGGSGIKTSIDELAASCLKFDKSESPRLVHRLDRDCSGLLVLARTQTAATVLHSIFREKTTGASAYGVKKNVKSLKRKYMALVIGCPPRQRGQISAPLRKVVVDDGKSERITVNDNGELVSTQHAITEYRVIESSPHGYTWLELRPLTGRKHQLRVHCAEVLGTPIVGDYKYGWQAHKAREPFVSSENNPTKQSSSPFGLDLDGGDVSSKQPHLHLHSKQIDLPNISQLLEKMQVSSDSDISDLDSLKFDAPLPSHMQLSFNLLKSRVETCDKN
Protein: Trans-activating transcriptional regulatory protein (Immediate early protein 1) (IE-1) (P11138)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: Regulatory transcriptional protein, which trans-activates gene expression from early baculovirus promoters. Can also trans-activate its own promoter, suggesting an autoregulation during infection of host cells. Promotes also viral DNA genome replication via the N-terminal region.
Subcellular location: Host nucleus {ECO:0000269|PubMed:12186932}.
Interaction partners:
Sequence:
MTQINFNASYTSASTPSRASFDNSYSEFCDKQPNDYLSYYNHPTPDGADTVISDSETAAASNFLASVNSLTDNDLVECLLKTTDNLEEAVSSAYYSESLEQPVVEQPSPSSAYHAESFEHSAGVNQPSATGTKRKLDEYLDNSQGVVGQFNKIKLRPKYKKSTIQSCATLEQTINHNTNICTVASTQEITHYFTNDFAPYLMRFDDNDYNSNRFSDHMSETGYYMFVVKKSEVKPFEIIFAKYVSNVVYEYTNNYYMVDNRVFVVTFDKIRFMISYNLVKETGIEIPHSQDVCNDETAAQNCKKCHFVDVHHTFKAALTSYFNLDMYYAQTTFVTLLQSLGERKCGFLLSKLYEMYQDKNLFTLPIMLSRKESNEIETASNNFFVSPYVSQILKYSESVQFPDNPPNKYVVDNLNLIVNKKSTLTYKYSSVANLLFNNYKYHDNIASNNNAENLKKVKKEDGSMHIVEQYLTQNVDNVKGHNFIVLSFKNEERLTIAKKNKEFYWISGEIKDVDVSQVIQKYNRFKHHMFVIGKVNRRESTTLHNNLLKLLALILQGLVPLSDAITFAEQKLNCKYKKFEFN
Protein: Possible muconolactone isomerase (O07243)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible beta-1,3-glucanase
Sequence:
MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDPIRMP