wanglab/gogpt-training-data huggingface dataset:
Protein: Glycine receptor subunit alpha-3 (P24524)
Organism: Rattus norvegicus (Rat)
Function: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure. Plays an important role in the down-regulation of neuronal excitability (By similarity). Contributes to the generation of inhibitory postsynaptic currents. Contributes to increased pain perception in response to increased prostaglandin E2 levels (By similarity). Plays a role in cellular responses to ethanol.
Subcellular location: Postsynaptic cell membrane {ECO:0000305|PubMed:19723286}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O75311}. Perikaryon {ECO:0000269|PubMed:19723286}. Cell projection, dendrite {ECO:0000269|PubMed:19723286}. Synapse {ECO:0000269|PubMed:19723286}. Cell membrane {ECO:0000269|PubMed:15131310, ECO:0000269|PubMed:19723286, ECO:0000269|PubMed:23613537, ECO:0000269|PubMed:23834509, ECO:0000269|PubMed:23895467, ECO:0000269|PubMed:25445488}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O75311}. Note=Partially colocalizes with GPHN that is known to mediate receptor clustering at postsynaptic membranes. {ECO:0000269|PubMed:19723286}.
Interaction partners:
- Glycine receptor subunit beta
- Centrosomal protein of 44 kDa
Sequence:
MAHVRHFRTLLSGFYFWEAALLLSLVATKETNSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRLSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSADEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHHQQD
Protein: Large ribosomal subunit protein uL29m (54S ribosomal protein L4, mitochondrial) (YmL4) (P36517)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein uL23m
- Large ribosomal subunit protein uL22m
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein uL16m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein uS5m
- Large ribosomal subunit protein mL41
Sequence:
MWKRSFHSQGGPLRARTKFTKPKPKQPVLPKDKIRPPTQLTHHSNNLRITEPIPPTTSNLRCPDDHPLWQFFSNKKFIRSADDLPPSSHIRPWSIPELRHKSFNDLHSLWYNCLREQNVLARENHLLKNIVGSTHDEFSELSNSIRTTMWQIRHVLNERELAYSASREFLQDESERKKFLDTLANDYFLNKDIPDDEVASMLTRFQLAIFGISETIQDNTVDINFIDGIKFLANLKLQRFKDSNDLISEISQEPITDVGESFILFTSDFEPHAVQEACVAIKDLRKSPDNKVPKLDELPTVRKYLKQLIHASSVEQATA
Protein: O-GlcNAcase NagJ (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Hexosaminidase B) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Q8XL08)
Organism: Clostridium perfringens (strain 13 / Type A)
Function: Binds carbohydrates. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. Can bind and deglycosylate O-glycosylated peptides from mammals. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro).
Interaction partners:
- Probable PTS system
- Probable PTS system
- Hyaluronoglucosaminidase
- exo-alpha-sialidase
- Probable PTS system enzyme
- PTS EIIB type-1 domain-containing protein
Sequence:
MKRKMLKRLLTSAFACMFIANGLITTTVRAVGPKTGEENQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYGTPWTHKDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPENEMQRMQELIDASAENKVDFVFGISPGIDIRFDGEAGEEDFNHLIAKAESLYDMGVRSFAIYWDDIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRTYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYNRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSSFAVISEKVAQSFIQEALSFDLTLINPRTVKITASSEETSGENAPASFASDGDMNTFWHSKWSSPAHEGPHHLTLELDNVYEINKVKYAPRQDSKNGRITGYKVSVSLDGENFTEVKTGTLEDNAAIKFIEFDSVDAKYVRLDVTDSVSDQANGRGKFATAAEVNVHGKLKEAAEVTGSVSLEALEEVQVGENIEVGVGIDELVNAEAFAYDFTLNYDENAFEYVEAISDDGVFVNAKKIEDGKVRVLVSSLTGEPLPAKEVLAKVVLRAEAKTEGSNLSVTNSSVGDGEGLVHEIAGTEKTVNIIEGTSPEIVVNPVRDFKASEINKKNVTVTWTEPETTEGLEGYILYKDGKKVAEIGKDETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRTAR
Protein: Ribulose bisphosphate carboxylase small subunit 1A, chloroplastic (RuBisCO small subunit 1A) (P10795)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:12766230}; Peripheral membrane protein {ECO:0000269|PubMed:12766230}. Plastid, chloroplast stroma {ECO:0000269|PubMed:12766230, ECO:0000269|PubMed:28839179}.
Interaction partners:
- Ribulose bisphosphate carboxylase large chain
- Phosphoribulokinase, chloroplastic
- Putative uncharacterized mitochondrial protein AtMg00280
- Phosphoglycerate kinase 1, chloroplastic
- Phosphoglycerate kinase 3, cytosolic
- Phosphoglycerate kinase 2, chloroplastic
- Phosphoglycolate phosphatase 1A, chloroplastic
- Ribulose bisphosphate carboxylase large chain, catalytic domain-containing protein
- D-glycerate 3-kinase, chloroplastic
- Phosphoglycolate phosphatase 2
Sequence:
MASSMLSSATMVASPAQATMVAPFNGLKSSAAFPATRKANNDITSITSNGGRVNCMQVWPPIGKKKFETLSYLPDLTDSELAKEVDYLIRNKWIPCVEFELEHGFVYREHGNSPGYYDGRYWTMWKLPLFGCTDSAQVLKEVEECKKEYPNAFIRIIGFDNTRQVQCISFIAYKPPSFTG
Protein: Ephrin-B1 (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (XlERK) (O13097)
Organism: Xenopus laevis (African clawed frog)
Function: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). May have a role in the developing mesenchymal and nervous tissue.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
Sequence:
MEGLRRLLGLLLVLYRLCSALGKNLEPVTWNSQNPRFISGKGLVLYPEIGDRLDIICPKGDSSQPYEYYKLYMVRRDQLEACSTVIDPNVLVTCNQPGKEYRFTIKFQEFSPNYMGLEFRRNQDYYITSTSNSTLQGLENREGGVCQTRSMKIIMKVGQDPNAVPPEQLTTTRPSKEADNTGKIATFGPWNGPVENPGKSDTNLSDKPTAGGGVDGFFNSKIAVFAAIGAGCVIFILIIIFLVVLLIKIRKRHRKHTQQRAAALSLSTLASPKCSGNAGSEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
Protein: Putative transposase Rv3428c (Q50700)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Putative ATP-binding protein Rv3427c in insertion sequence
- Possible transposase
- Ribonucleoside-diphosphate reductase subunit beta nrdF2
- Possible transposase for insertion sequence element IS1533
- Possible transposase
- UPF0182 protein Rv3193c
- Probable transposase for insertion sequence element IS1533
Sequence:
MATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVAVWAFVMVLAFSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKDKPRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIGTVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTAELVGPASQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPASTAGGVPARP
Protein: V-type proton ATPase proteolipid subunit (F1QSP4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000256|ARBA:ARBA00029431}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00029431}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000256|ARBA:ARBA00004644}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004644}. Vacuole membrane {ECO:0000256|RuleBase:RU363060}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU363060}.
Interaction partners:
- V-type proton ATPase subunit F
- V-type proton ATPase subunit d 1
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase subunit H
- Vacuolar proton pump subunit B
- V-type proton ATPase subunit D
- ATP synthase F
- ATPase H+-transporting V1 subunit E1b.
- Vacuolar proton pump subunit B
- ATP synthase subunit alpha
Sequence:
MDTQNPQYSPFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNIGDKISLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTKG
Protein: SKI family transcriptional corepressor 2 (Functional Smad-suppressing element on chromosome 18) (Fussel-18) (LBX1 corepressor 1-like protein) (Ladybird homeobox corepressor 1-like protein) (Q2VWA4)
Organism: Homo sapiens (Human)
Function: Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system.
Subcellular location: Nucleus {ECO:0000269|PubMed:16200078}. Cytoplasm {ECO:0000269|PubMed:16200078}.
Interaction partners:
Sequence:
MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSFFITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNTSFPVFNNFQDQMKRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS
Protein: NDR1/HIN1-like protein 1 (Q9SRN0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in plant immunity.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9FNH6}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- RBR-type E3 ubiquitin transferase
- Late embryogenesis abundant
- Non-race specific disease resistance protein
- AT5g48790/K24G6_12)
- Trafficking protein particle complex subunit-like protein
- Cysteine-rich receptor-like protein kinase 7
- Protein RER1B
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Protein transport protein SEC24 B
- CRS1 / YhbY
Sequence:
MKDCENHGHSRRKLIRRIFWSIIFVLFIIFLTILLIWAILQPSKPRFILQDATVYAFNVSGNPPNLLTSNFQITLSSRNPNNKIGIYYDRLDVYATYRSQQITFPTSIPPTYQGHKDVDIWSPFVYGTSVPIAPFNGVSLDTDKDNGVVLLIIRADGRVRWKVGTFITGKYHLHVKCPAYINFGNKANGVIVGDNAVKYTFTTSCSVSV
Protein: Benign gonial cell neoplasm protein (Q9W1I2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Essential cystoblast differentiation factor required for Bam function in asymmetric division of the germline stem cells.
Interaction partners:
- Corona
- Protein bag of marbles
- Protein hu-li tai shao
- Uncharacterized protein, isoform B
- Uncharacterized protein, isoform B
- FI03705p
- Uncharacterized protein
Sequence:
MNHIIQDKYIPQQLLYFLAGRRCCQQFPCTFRTSEHEAFANNARSLGLRSQVVHVNGNSCVKVYKQACRHYLEEPKTLVLSSGATLNMFTLLSRKSLMGKEDLELYADLVSMKANASDLPSLHLPLPAIRPPNLRFWTEAQLNFLTAFLGHSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRSLTSQQFRNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTYYHIVKLNYMILSHCLTGSLQECSIFLLYDNMRNDYLQALVNASDETVKVVLATDIIESLCLKVPFKYQIDTACRLNNVYDTTSCSGDDRFEWVAKDALLRRELILQPNKGDVQCFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLLSPNTIISEYLGITISPPPLINVHHAVQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIKKERTYLSDNQFSDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQLTSIRSEIVSSLRAANLIHSRGKLSMNNLNQMSCNWHMVKAALTGGMYPNIYAVDTRKSSLKSAFSGNVSMHPNTVLRDFLEPLNISAQSFRTPWIVCNRQKSHIVYATLVVPLAVAMFSGHPRIRLSPICDSEMSLTDRNVNVFIDEWIWMVMSKATAEMVMRTRYYFFKMYHDLLKHCSELDMWRRDCEPVSQYTVLTDTLSKIFESEDGFVGFFKPPPITFLPTPQLPSLYLLSVNAHFSWAREVEENMLSKPHHFNSHFIERQFFVLYAGGDCEEFHSRNTPAFIESVLGKFVRPIDTPNRHIFVILYRKDPDMMLSISRAKFVNGVFMLQEYFRNNIPVFEILDACVSLNVQTPVFDGRLMSALIDKRVGNLIMELFAFRHHWIHKR
Protein: Taste receptor type 2 member 13 (T2R13) (Taste receptor family B member 3) (TRB3) (Q9NYV9)
Organism: Homo sapiens (Human)
Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Taste receptor type 1 member 2
Sequence:
MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIWEILVSWFLALHYLAIFVSGTGLRIMIFSWIVSNHFNLWLATIFSIFYLLKIASFSSPAFLYLKWRVNKVILMILLGTLVFLFLNLIQINMHIKDWLDRYERNTTWNFSMSDFETFSVSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHRDPRTKVHTNALKIVISFLLFYASFFLCVLISWISELYQNTVIYMLCETIGVFSPSSHSFLLILGNAKLRQAFLLVAAKVWAKR
Protein: Protein MUM3 (Muddled meiosis protein 3) (Q08750)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the organization of the outer spore wall layers and especially in the assembly of the chitosan layer.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Outer spore wall protein 1
- Uncharacterized acyltransferase YDR018C
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
Sequence:
MGFVDFFETYMVGSRVQFKQLDISDWLSLTPRLLILFGYFYLHSFFTAINQFLQFINTNSFCLRLHLLYDRFWSHVPIIGEYKIRLLSRALTYSKLKIIPTLDKVLEAIEIWFQLHLVEMTFEKKKNVQIFITEGSDDLNFFKDSKFQTTLMICNHRSVNDYTLINYLFLKSCPTKFYTKWEFLQKLRKGEDLAEWPQLKFLGWGKMFNFPRLDLLKNIFFKDETLALSSNELRDILERQNNQAITIFPEVNIMSLELSIIQRKLHQDFPFVINFYNLLYPRFKNFTTLMAAFSSIKNIKRKKNRNNIIKEARYLFHRELDKLVHKSMKMESSKVSDKTTPPMIVDNSYLLTKKEEISSGKPKVVRINPYIYDVTIIYYRVKYTDSGHDHTNGDLRLHKGYQLEQISPTIFEMIQPEMESENNIKDKDPIVVMVNVKKHQIQPLLAYNDESLEKWLENRWIEKDRLIESLQKNIKIETK
Protein: asparagine--tRNA ligase (EC 6.1.1.22) (Q7JZR5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Glutamyl-tRNA
- Tyrosine--tRNA ligase
- isoleucine--tRNA ligase
- Glutamyl-tRNA
- Methionine--tRNA ligase, mitochondrial
- Methionine--tRNA ligase, cytoplasmic
- Asparagine--tRNA ligase, cytoplasmic
- Isoleucine--tRNA ligase, cytoplasmic
- Tyrosine--tRNA ligase, mitochondrial
Sequence:
MLFLRRFYSKSGRIAQILKTNKPGDSLAIQGWIKNVRRLKNNTFLDINDGSTSSRFQVVVPRTPENQHLAPGSVIAAVGKIQVAPNGSFELHANQVEMLAEGRLQEGYPFSPKQKHPPEYVREHLHLRSRVDFVAAQMRVRHKAQKAIHDYMDDQDFVQINTPLLTTNDCEGAGEVFRVQPDSQDLLKQMNRPNIPMEQSYFDSKVFLSVSGQLHLEAMTYGLGKTYTLSPAFRAENSKSPLHLAEFYMFEAELAHLEEMEKLAQFIEQMLKSVTNRLLETSGEDLSFCQRNSNSNSDLPWLQVPWKIMSYDEALQVLQENKDSLKTPISLNEGFSKDQELFLVAHCGAPVFVVDWPAQQKPFYMKVSRSNPNRVHALDLLMPAVGELCGGSLRESDPAILKSHPHLPKDLEWYVDLRKYGGVPTGGFGMGFERYLQLVTGVKNIRDVIPFPRYPHSCKM
Protein: Sp1, isoform D (A8JUN6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLTDMTPTAGQLYGSQIPAMGMNISNIATHLQKPQVNPDHPSLRGTPLAMLAAQCNKLSNKSPPPLADAAVGKGFHPWKKSPNSPAAGSSGSSGGGGGGGGSSAGQHSPCAISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGSTGSSSSASGSQSSSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGWWDMHSAAGSWLDMGGAGMHSTMANYASENYSSALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTHNGTANHQANGHNGGLKKGSSESCSDSEEAANQSGESNGLGGVGSGPQTGGAGGGGGGSSSGNGAGTLAVSGSVTTGAGAGSGTGSSNSNSNSGGSSGSVSGSVSGSGSHPGTPTSLHAHSANGTSSSLLGGGLHLATPHQMVAAGGSPVMLHQQQQQQQHQQQQQQQQQQQHQQQQQQQHQQQQQQHQQQQQQHHQQQQQHHHQQFGQQQHPHAHHLHHHAHHAHHLATGGSPGLDPSSLVDIKPPMV
Protein: Zinc finger protein 221 (Q9UK13)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MISPSLELLHSGLCKFPEVEGKMTTFKEAVTFKDVAVVFTEEELGLLDPAQRKLYRDVMLENFRNLLSVGNQPFHQDTFHFLGKEKFWKMKTTSQREGNSGGKIQIEMETVPEAGPHEEWSCQQIWEQIASDLTRSQNSIRNSSQFFKEGDVPCQIEARLSISHVQQKPYRCNECKQSFSDVSVFDLHQQSHSGEKSHTCGECGKSFCYSPALHIHQRVHMGEKCYKCDVCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHSRSALNVHCKLHTGEKPYNCEECGKAFIHDSQLQEHQRIHTGEKPFKCDICGKSFRVRSRLNRHSMVHTGEKPFRCDTCGKNFRQRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFCKHQMVHTGEKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYTNSRRSSHQRSHNGEKPYNCEECGKDYKRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLKHQRLHSGEKPFKCEECGKRFTQSSQLHSHQTCHTGEKLYKCEQCEKGYNSKFNLDMHQRVHGGERPYNCKECGKSFGWASCLLKHQRLHSGEKPLKSGVWEEIYSEFTASFTSVSLCGRKAI
Protein: Membrane-bound maltase-glucoamylase (EC 3.2.1.20, EC 3.2.1.3) (Q6XK24)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MAGRRFKKFSKLELVLIVLLLVLFIIAVVLIVLLANSTPENAIGAETTGTPDTTVTRTTLNSPNCPVLSELERINCIPDQSSNKGTCDERGCCWDPQGSISVPCYYSRNHGYKMESDVVNTNAGFTATLKNLPSAPVFGNSIENILLTAEYQTSNRFHFKLTDQTKKRYEVPHEHVQPFSGNAPSSLNYKVEVSKEPFSIKVTRKSNNRVLFDSSIGPLLFSDQFLQFSTHLPSANVYGLGEHVHQQYRHNMNWKTWPMFSRDTTPNEDGTNLYGVQTFFLCLEDNSGLSFGVFLMNSNAMEVTLQPTPAITYRTTGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWTLGFQLSRYDYXSLDNMKAVVERNRAAQLPYDVQHADIDYMDQKKDFTYDPVNFKGFPEFVKELHNNGQKLVIILDPAISNNSFSSNPYGPYDRGSAMKIWVNSSDGISPVIGKVWPGTTVFPDYTSPNCAVWXTKEFELFHKEVEFDGIWIDMNEVSNFIDGSFSGCSQNNLNXPPFTPKVLDGY
Protein: DNA topoisomerase 6 subunit A (AtTOP6A) (EC 5.6.2.2) (Meiotic recombination protein SPO11-3) (AtSPO11-3) (Protein BRASSINOSTEROID INSENSITIVE 5) (Protein ROOT HAIRLESS 2) (Q9LZ03)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. Involved in cell-elongation processes.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03164}.
Interaction partners:
- DNA topoisomerase 6 subunit B
- DNA-binding protein BIN4
- DNA-binding protein RHL1
- Meiotic recombination protein DMC1 homolog
- DNA repair protein RAD51 homolog 1
- Meiotic nuclear division protein 1 homolog
- Homologous-pairing protein 2 homolog
- Type 2 DNA topoisomerase 6 subunit B-like
- WD repeat-containing protein VIP3
- Double-strand break repair protein MRE11
Sequence:
MADKKKRKRSKDDEAEELPFKSILESDDVITELLKSYISSSIKAAAGAGGASSSSSKPLTLADLSLSSSCREVADLSLSSVQTEIETVIVQIARSILAGDGFSFSVPSRAASNQLYVPELDRIVLKDKSTLRPFASVSSVRKTTITTRILALIHQLCLRNIHVTKRDLFYTDVKLFQDQTQSDAVLDDVSCMLGCTRSSLNVIAAEKGVVVGRLIFSDNGDMIDCTKMGMGGKAIPPNIDRVGDMQSDAMFILLVEKDAAYMRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKIPEQCRLPMTEQDIKTGKDMLEEDFVKKNPGWVEELNLMVKTKQKAEIQALSSFGFQYLSEVYLPLKLQQQDWL
Protein: Small proline-rich protein 2G (O70558)
Organism: Mus musculus (Mouse)
Function: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MSFQEQQCKQPCQPPPVCPPPKCPEPCPLPKCPEPCPPPKCPEPCPEPCLPSPCQQKCPPVQTPPPCQQKCPPKSK
Protein: Abp1p (Q5AFA8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Regulator of cytoskeleton and endocytosis RVS167
- Adenylyl cyclase-associated protein
- Fimbrin
- SH3 domain-containing protein
- SH3 domain-containing protein
- Actin
- Actin cytoskeleton-regulatory complex protein SLA1
- Actin cytoskeleton-regulatory complex protein PAN1
- RVS161-like protein RVS162
- Sla2p
Sequence:
MEKIDINTNSNKIQQAYDKVVRGDPNATFVVYSVDKNATMDVTETGDGSLEDFVEHFTDGQVQFGLARVTVPGSDVSKNILLGWCPDSAPAKLRLSFANNFADVSRVLSGYHVQITARDQDDLDVNEFLNRVGAAAGARYSTQTSGLKKPSPAAPKPTSKPVVAKSSSASKPSFVPKSTGKPVAPAKPKPKNITKDAGWGDAEDVEERDFDKKPLDNVPSAYKPTKVNIDELRKQKSDTTSSTPKTFKSEPQEEKNDDDGQSKPLSERMKAYDQPSSSDGRLTSLPKPKIGHSVADKYKASASGNGAAPAFGAKPAFGTQSVDSRKDKLVGGLSRDFGAENGKTPAQIWAEKRGKYKTVASDEKETNSSEKVDEPEEHHAADLAKKFEEKANIAGDTPSLPTRNLPPAPPARETAIPSNEKDKEEKEEEEQAPAPSLPTRNLPPPSQRQPEPEPEPEEEEEEEEEEAPAPSLPARNLPPAPKAEAEESKKQSTTATAEYDYEKDEDNEIGFSEGDLIIDIEFVDDDWWQGKHAKTGEVGLFPATYVSLNEKAADKEEEAPAPAPAPSLPSREETQAAPALPSRSEQKPESKTATAEYDYEKDEDNEIGFSEGDLIVEIEFVDDDWWQGKHSKTGEVGLFPANYVVLNE
Protein: Protein LDB19 (Low dye-binding protein 19) (Q12502)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in protein-linked oligosaccharide phosphorylation since the deletion reduces the negative charge of the cell surface. Involved in the resistance to EDTA, cadmium chloride, cycloheximide, 6-dimethylaminopurine, methyl caffeate, beta-chloro-L-alanine, caffeine and cerulenin.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Golgi apparatus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- E3 ubiquitin-protein ligase RSP5
- Arrestin-related trafficking adapter 3
- Protein ECM21
- Arrestin-related trafficking adapter 6
- Protein ROG3
- Protein ROD1
- Ubiquitin ligase-binding protein BUL1
- High-affinity methionine permease
- Ubiquitin ligase-binding protein BUL2
- Arrestin-related trafficking adapter 10
Sequence:
MAFSRLTSTHQSNHNGYSNSNKKGQSLPLTLSIDVESPPCVLYGSAMESSGAVLSGLFTVTVVDPYSSAEDKSLKNTESNVSTTSKSLKRKSTFGSALSSRLSSLSASTSNISPSTSSTSISHSPTPANLRIMAGYTKITITSVTLSLVQKIHFHKPFVPNISSMQTCMNCKTKITNMKSWEIQSNTQDLSVGSHSYPFSYLIPGSVPCSSSLGATAETQVKYELIAVVTYIDPHRNSFSSGHSTPRKEGSSSKKRLLQLAMPIAVTRSIPRGPDKNSLRVFPPTELTAAAVLPNVVYPKSTFPLEMKLDGVSSGDRRWRMRKLSWRIEETTRVKAHACPVHKHELRQLEEQVKIKESEKSKKPRSHIKRYGELGPQIRVAVNSLENMPSQRLPGEPGREQAPNSSGPASTGNVGLDDENPVNEDEEDQPGSEFIHPSDDALRQELLMQQQRARQQQLQQELKNNSSLFTEEVRIISKGEMKSGWKTDFDNNGKIELVTEIDCMGLNSGVSNPVMHASTLQTPSTGNKKPSINVACDIQDPNLGLYVSHILAVEIVVAEETLQYANGQPIRKPNSKNKKETNNNTMNVHNPDQRLAELSPIFANRNTPKVRRMGPEDITPVNSNKSNHSTNKEKASNGASNSNIVSVPTGAARVLRMQFRLTVTERSGLGISWDEEVPPIYQDVELLSPPCYELSINNGIKNKLYSTMSTPVRSEDDFVGGSDEDIGNYESQGLEPGPNVQEVTITQNKLTIPPTAHHYQPASSSQRSLTTVQSPPLESVVSVQGSVPFRGHVLTPHSTRDIRIQNFSDFLDSNRITQ