wanglab/gogpt-training-data huggingface dataset:
Protein: CgABP260 (Q90WF0)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MNSSGYEETAVPEDAEELPAAEKELAEDAPWKKIQQNTFTRWCNEHLKCVNKSISDLQRDLGDGLRLIALLEVLSQKKMGRKHHPRPNFRQMKLENVSVALEFLERERIKLVFIDSKAIVDGNLKLILGLVWTLILHYSISLPMWEEEEEGARQQTPKQRLLGWVQHRVPQLRITNFNRDWNDGRALGALVDNCAPGLCPDWQSWDPAQPVQNAREAMQQADDWLGVPQVIAPEEIADPNVDEHSVMTYLSQFPKAKLKPGAPLRPRAVRPERVRAYGPGLEPQGNVVLQPARFTVETWTRARQVLENARDHRAHHEEAQVVANNDEKRTFSVTYVPKVAGLHKVTVLFGGQNIPGSPFVGVAMAHGDASKVSARGPGIEPSGNVANKPTYFDIYTAGAGSGDVGVVLEDPAGPRDTVEGDMEDRGDSTFRCSYRPTLPGPHRVAVTFAGAHIPNSTFCVNVAEACNPSACRAWGRGLQPKGLRVHETADFRVHTNAPAELRVTVPDRGTEVPVSVRPTADGVYECEYRPTVAGTHSVSITWGGYSIPRSPLEVEVSPAAGAQKVRAWGPGLHGGVVGDSADFVVEAIGDDVRTLGFSIEGPSQPKIESDDPGDGSCDVRYWPTEAGPYPVHVVCDDEDIARSPFMAHIRPAAPDCSPDKVKVWGPGLEPTGVIVNRPTEFCVDARAAGKGGLHIYAQDADGCPVDIAVKDNGDGTFSCHYVPSKAIKHTVIVTWGGVNVPRSPFRVAVGKGSHPGRVRVYGPGVERAGLTAGEPTYFTVDCSDAGQGDVSIGIKCCPALPGAAEADIDFTIIKNDNDTFTVKYTPPCAGLLTVMVLFGTQELPCSPFRITVAPAHDSSKVRAEGPGISRTGVESGRPTHFTVQTRGAGKAPLDVQFGGAAQSGVSDVQIIDNGDYSHTVKYTAMRQGELSVGVTYGGDPIPKSPFPVTVAPPLQLDKVSVQGLSSKVPVGAPQSFSVLSSGAGGQGALSVTAMGAGRRSVPVAVESAGPGLHRARFTAAEEGQLRFDVTYDGHPVPGSPFVVDAVLPPDPSKVHAFGPGLHGGVAGSPATFTISTRGAGSGALGLTVEGPREAELECHDNGDGSCSVRYVPPEPGDYSLNILFAGTHVPGSPFRAAVRPRFDATKVRADGPGLRSGRVGQIATFAVDCRDAGEAELNIEIRHELGARPEVRIHDNGDGTYGISYTPARAGAYTVTVSYGGVPVPHFPACVTVEPDVDLSAIAVYGTGVEPRGPLRDVSTEFTVDARAVVPSGGPHVGARVTAPSGATTDCSVSDGGDGTYRVRYTPREEGVHQVEVTFQEVALPQSPFAVAVAEGCDPTRVSAHGPGLESGLVGRANCFTVQTRGAGTGGLGLAIEGPSEAKMSCQDNKDGSCSVEYVPFAAGDYDVNITFGGRPIPGSPFRVRVSEPVDASQVRCSGAGLGPTVRARLPHSVNVDCSAAGRAALDVTLLGPTGTPEPVEVRDNGDGTHSVTYSPTAVGPHSLSIAYGGQEVPRTFKLQAVPHDASRVLASGPGLSPSGVPASLPVEFAIDARRAGQGVLTVQILDPEGRPTEASIEDHGDGTFTVRYLPRLVGRYSITVRYGGDDIPASPFCIHGAPSGNASKCHVTGGCAFPTLRPGERTLLAVDARAAGPGKVTCSVLSPDGAEVDVDVAENPDGTFHVSYTAPEPGSYGLTVRFGGQHVPNSPFRIVATAEPPRPRDLRPFSLDLPCAPLKGDITAEVRTPSGRTARAEVAQSGDGTVAVRFEPSEKGRHLMELRCDGDPLPGSPLQFYVDAVDARHVSAYGAGLSHGVVNKACSFTVITKGAGEGGLSLAVEGPSKAELSCHDNHDGTCTVSYVPTAPGDYSVIVRFDDEHIPGSPFTAKITGDDSLRTSQLNVGTATDVSLKISETDLSQLTASIRAPSGSEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKGGQHVTNSPFKIVVGPSEIGNAERVKVWGTGLSEGRTFQLAHFVVDTRSAGYGGLGLSVEGPSKVDIHCEDAEDGTCKVSYCPTEPGSYRLSVKFAEQHVPGSPFTVKVSGEGRVKESITRARQAASIAAIGSACDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETTREVRVQESTRVGAEPFHGVFGGFLGGFGAAARGQEDAAPPELTAQVLSPSGQHSEAEVQAGPGSAYRVRFVPEELGPHSVAVKFRGQHVPGSPFPFTVGPLGEGGAHRARAGGPGLQRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEINFEDRKDGSCGVTYLVQEPGDYEVSIKFNEEHIPDSPFVVPVASRSDAAQHSTVSSAQEALRVNHPAALSVHLNGARRPFDAKVLSPTGTVSECSVSEIDPDLYSIGFLPVENGVHAVEVRLNGRHVPGSPFNVRVGEQSHDADPGLVTAYGAGLQGGVTGVRSEFVVKTANAGSGALSVTIDGPSKVTLDCVECAEGHRVTYTPMAPGNYLISIKYGGPHHIVGSPFKAKVTGPRLSGGHSLHETSSVLVETVTRGALGPPGFGTLPKFSSDASKVVARGPGLSTAFVGQKNHFTVDCSKAGSNMLMVGVHGPKTPCEEVYVKHVGNRLYNVTYTVKEKGEYVLILRWGDDSVPGSPFRVTVP
Protein: Mitochondrial arginine transporter BAC1 (Mitochondrial basic amino acid carrier 1) (AtMBAC1) (Q84UC7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitochondrial arginine transporter that catalyzes the counter-exchange of arginine with lysine, ornithine, arginine and histidine. Substrate preference in reconstituted proteoliposomes is arginine > lysine > ornithine > histidine. May be involved in the delivery of arginine, released from seed reserves, to mitochondrial arginase and the export of ornithine.
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Arginase 1, mitochondrial
- Arginase 2, chloroplastic/mitochondrial
- Urease
- Ornithine aminotransferase, mitochondrial
- Ornithine transcarbamylase, chloroplastic
- Cationic amino acid transporter 4
- ACT domain-containing protein ACR1
- Probable LRR receptor-like serine/threonine-protein kinase At5g63710
Sequence:
MGESKTTTGEGFGFYKEYVAGMMAGLATVAVGHPFDTVKVKLQKHNTDVQGLRYKNGLHCASRILQTEGVKGLYRGATSSFMGMAFESSLMFGIYSQAKLFLRGTLPDDGPRPEIIVPSAMFGGAIISFVLCPTELVKCRMQIQGTDSLVPNFRRYNSPLDCAVQTVKNDGVTGIFRGGSATLLRECTGNAVFFTVYEYLRYHIHSRLEDSKLKDGYLVDMGIGVLTGGLGGIACWSAVLPFDVAKTIIQTSSEKATERNPFKVLSSIHKRAGLKGCYAGLGPTIVRAFPANAAAIVAWEFSMKMLGIKRD
Protein: Anion transporter SULP-2 (STAS domain-containing protein) (G5EDS5)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKQEEYDQMYSFNREGNETWVKKKINNYCTFLSKDGIRKIILRRVPVIDWIGSYQINNFASDFIAGLTMGVYNVPQAMSYSILAGLPPVYGLYASFFPPFLYSIFGSAKHSSIGVFSITCLMVDKCVKKMLKFRNENPEKFTSVQAIEIVTSLCILTGIIQAVMAIFRCDKPMKFLGAPAISAITFSACFFGVVSQIPKLCGFSVPSRNEHWFSLVHSILDIFENCHKSNTATLCISASALVFLIGSRIFIEPFFKNHKKLQSIPFPKELITIVIATSASYFFDFEHRFGVKTLHTVPRGFPYPDVPRIDIWPYIFQDALSIAVVAYAVTMAMGQEFATKHRYRIDSNQELLALGFINIGSSFFSVFPTSASFSRTLVNERSGAKTQLSGITSACFMALVITTIGPYLASLPSCILSAIVIVVLESMLRKCTVLPGLWRCSKHDFWIWIITAVVTLSSDIAQGVAAGIFTAIFTIAIQSQQPTIKLLGQIRPNDFRPMNHYSLAKETSFRIIRFDAPLIFANVEKFLDNVRDSTSATTKKRSASCDSQEDIEWSAIILDCHTWIYTDSMGIAAVKQINEELRQIRILLLFANLKSSLRRQYGNAGLIGEGNIGRNQMYPSIQDALDSAHELIKNHKMFFDCEKSMPPEKIVP
Protein: Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Q29RW1)
Organism: Rattus norvegicus (Rat)
Function: Muscle contraction.
Subcellular location: Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Interaction partners:
- Myosin light chain 1/3, skeletal muscle isoform
- Troponin I, fast skeletal muscle
- Myosin-7
- Myosin-6
- Myosin regulatory light chain 11
- Troponin C, skeletal muscle
- Myosin light chain 3
- Myogenin
- Myosin regulatory light chain 12B
- Actin, alpha skeletal muscle
Sequence:
MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESYVKATVQSREGGKVTAKTEGGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEAPSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQVMSNKKPELIEMLLITTNPYDFAYVSQGEITVPSIDDQEELMATDTAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAMYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSGGQAAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFRKMMERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE
Protein: FYR C-terminal domain-containing protein (Q57VV2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription activator, putative
Sequence:
MFRVVSFGSLIQDSRFYFKRNGRVTTMYPDGYTIQRRVFSKGRRTRAKITLPGDDAKNDLGEVYYTATIKRRDDGGPCFQVVRSDKPDVIHSGDQCSPAWRKALEAAKQDFPDAHKELAYVGSDDKGCMIVQGAILFGLTAKPVVDELNKMAKALSINEWLSTISADTKSLGDPIGSPIPSSSSQPRKPKQQLVTSSQPSQSSSWKTRGKKSVEAPEDDDVPYCVRLSNSEVSASVPCSICGSTTPFCPITGKRHDTTGKGGRGRKKSELTEGAVAPSEPTGKKRGRRKKQPRDDDGAEGSQNMSASSGDAVKRRRTSDGATERGPSTRDAKRQMLLFENNGNAVDGSLANGEVPYAPPPVLFRPPLSPPQSKEALRVLQRTLQALSVVRTPFTSLLQLREPGVKKTTHASSKSDKGAGSQANIISVNGADTDGNDAAAARKQAEEGTQHFLDIVDMDKGTRARRYIKFMKLYTSERTKMDLLKKAANSNPDSS
Protein: SD14927p (Q8IG96)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
QDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQVVVAWPQPA
Protein: Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABAAR subunit rho-2) (GABA(C) receptor) (P56476)
Organism: Mus musculus (Mouse)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission (By similarity).
Subcellular location: Postsynaptic cell membrane {ECO:0000305|PubMed:16945976}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:25422464}; Multi-pass membrane protein {ECO:0000255}. Note=Located at the plasma membrane of astrocytes, in soma and to some extent in distal processes. {ECO:0000269|PubMed:25422464}.
Interaction partners:
- GABA
- Gamma-aminobutyric acid receptor subunit rho-1
- Gamma-aminobutyric acid receptor subunit gamma-2
- Gamma-aminobutyric acid receptor subunit theta
- Gamma-aminobutyric acid receptor subunit epsilon
- Gamma-aminobutyric acid receptor subunit gamma-3
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit alpha-2
- Gamma-aminobutyric acid receptor subunit alpha-5
- Gamma-aminobutyric acid receptor subunit alpha-3
Sequence:
MPYLMRLALVLFCLMALVESRKPRRKRWTGLLETSKPSHLYKKNLDVTKMRPGKPRPLLRVEDHDFTMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWRDERLAFPSSSNKSMTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDHRAVPARVSLGIMTVLTMSTIITGVNASMPRVSYIRAVDIYLWVSFVFVFLSVLEYAAVNYLTTLQEQKERKFREKLPCMCGMLHSRTMMLDGSYSESEANSLAGYPRSHILPEEERPDNIVVHLALNSELTSSRKKGLLKGQMGLYIFQNTHAIDKYSRLIFPAFYIVFNLIYWSVFS
Protein: Granzyme K (EC 3.4.21.-) (NK-tryptase-2) (NK-Tryp-2) (P49864)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic granule.
Interaction partners:
- Granzyme A
- Natural killer cell group 7 sequence, isoform CRA_a.
- T-cell surface glycoprotein CD3 delta chain
- Eomesodermin
- C-C motif chemokine 5
- Perforin-1
- T-cell surface glycoprotein CD8 alpha chain
- C-C motif chemokine receptor 7
Sequence:
MSFSSSALVFLVAGIYMSSESFHTEIIGGREVQPHSRPFMASIQYRGKHICGGVLIHPQWVLTAAHCYSRGHSPTVVLGAHSLSKNEPMKQTFEIKEFIPFSGFKSGTNDIMLIKLRTAAELNKHVQLLHLRSKNYIRDGTKCQVTGWGSTKPDVLTTSDTLQEVTVTIISRKRCNSQSYYNHKPVITKDMICAGDRRGEKDSCKGDSGGPLICKGVFHALVSGGYKCGISNKPGVYTLLTKKYQTWIKSKLAPSSAH
Protein: Dermaseptin PD-3-7 (O93455)
Organism: Agalychnis dacnicolor (Giant Mexican leaf frog) (Pachymedusa dacnicolor)
Function: Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
Subcellular location: Secreted {ECO:0000305|PubMed:9774745}.
Interaction partners:
Sequence:
MSFMKKSLLLVLFLGVVSLSNCEEEKGENENEDHEEHHEEKRLLGDLLGQTSKLVNDLTDTVGSIV
Protein: Branched-chain-amino-acid aminotransferase 1, mitochondrial (Atbcat-1) (EC 2.6.1.42) (Q93Y32)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Converts 2-oxo acids to branched-chain amino acids. Acts on leucine, isoleucine and valine (By similarity).
Subcellular location: Mitochondrion.
Interaction partners:
- Dihydroxy-acid dehydratase, chloroplastic
- 2-isopropylmalate synthase 1, chloroplastic
- 2-isopropylmalate synthase 2, chloroplastic
- Threonine dehydratase biosynthetic, chloroplastic
- 3-methyl-2-oxobutanoate hydroxymethyltransferase 1, mitochondrial
- 3-methyl-2-oxobutanoate hydroxymethyltransferase 2, mitochondrial
- Probable cystathionine gamma-synthase 2
- Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial
- Cystathionine gamma-synthase 1, chloroplastic
- Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial
Sequence:
MALRRCLPQYSTTSSYLSKIWGFRMHGTKAAASVVEEHVSGAEREDEEYADVDWDNLGFSLVRTDFMFATKSCRDGNFEQGYLSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRVLLFRPELNAMRMKIGAERMCMHSPSVHQFIEGVKQTVLANRRWVPPPGKGSLYLRPLLFGSGASLGVAAASEYTFLVFGSPVQNYFKEGTAALNLYVEEVIPRAYLGGTGGVKAISNYGPVLEVMRRAKSRGFSDVLYLDADTGKNIEEVSAANIFLVKGNTIVTPATSGTILGGITRKSIIEIALDLGYKVEERSVPVEELKEAEEVFCTGTAAGVASVGSITFKNTRTEYKVGDGIVTQQLRSILVGIQTGSIQDTKDWVLQIA
Protein: Nicotinic acetylcholine receptor Dalpha6 subunit variant type III (Q8T7S1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MDSPLPASLSLFVLLIFLAIIKESCQGPHEKRLLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHSGSCLYVPPGIFKSTCKMDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITNGEWYLLAMPGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKLTLGVTILLSLTVFLNLVAETLPQVSDAIPLLGTYFNCIMFMVASSVVLTVVVLNYHHRTADIHEMPPWIKSVFLQWLPWILRMGRPGRKITRKTILLSNRMKELELKERSSKSLLANVLDIDDDFRHTISGSQTAIGSSASFGRPTTVEEHHTAIGCNHKDLHLILKELQFITARMRKADDEAELIGDWKFAAMVVDRFCLIVFTLFTIIATVTVLLSAPHIIVQ
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q57TR7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MFSELGIALLTVAAFANGAKENVREFSDLCVLYSFLARPVPVPVIHGTDGTKSTPVTSVFQTALNEVIKLNLTVIDPKMSAVLADDKKYDKAAKILESQDVKGYFDKLSAETVQTMINEYPTIKPGEKEDKNFMKKFKVPVSESTATNVRPLMANLAAAAMQIKSELDTKLASLSSTRTRIRKLTVTAMFGQAVAENPTQPITADTQLDTLLTAQNFPWSDSAARDAACERPESNSAGPGKAIAADVVCLCSEHKNAASDSCTDTATSDTDNFGVGSGMKLKAFNRWKQLQTKCKEQNPAKAVTLNPTAITAALSAVFGNLGKNAITQASVTGKAATPVERHSYLGAYVVGGTTPTTCTSASWDPGSTAGKGLCISYENFLNKGKQVPWAAAVLDVADELHNLEDANADIITLYSRVCAIKKQMETLLLMGELLTPAAGPVLTTTTLKEKTVEEQNKFARFNSNETDCTTNGCDYDKTKKECKPKPGTENTAPPTGTGTAGATASTGCARHKDKTECDADKTGEKQNCAWRKGKEGEPEPEKELCRNGSFIANKKLALMAAAAFMCFLF
Protein: SET domain-containing protein 3 (Q10362)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Required for both gene activation and repression. Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis. Required for the transcriptional activation of genes with high activity (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Set3 complex subunit hif2
- Uncharacterized protein C22E12.19
- Histone deacetylase phd1
- Histone deacetylase clr6
- Paired amphipathic helix protein pst3
- Transcriptional regulatory protein rxt3
- RbAp48-related WD40 repeat-containing protein prw1
- Putative histone deacetylase complex subunit cti6
- SWIRM domain-containing protein laf2
- SWIRM domain-containing protein laf1
Sequence:
MWKIRCVCPFEDDDGFTIQCESCEVWQHAVCVNIDANNVPEKYFCEQCQPRPIDADKAHKIQLARLQREEEQSRILSRSRSSNNKRRTSFGKNGASPTHSASPRQGNNTGANGALFSQSTNSSNSGSYRNSVTGATLPNAHAPHSQNRRRRSNHLNNPPEAPITEASNEYVYSFHLEYVPLESNTFSASALEYSKNLDLKNLDESEVLMDGCQVVPISSSKFCCSRFGLVSTCEIPPNTPIMEVKGRVCTQNEYKSDPKNQYNILGAPKPHVFFDSNSQLVVDSRVAGSKARFARKGCQSNSVVSSVYMNGSNSVPRFILYSTTHIAPETEIIGDWTLDISHPFRQFAPGMSRPSFNMEELELLSEVLSTFLSFNECASQDKKNCVFSRVTKYIKAARRASTANRVSVAKDRLSLTPSSTPSTPSPAESLPQPSNPTSVYAKSLKEFWLDKYRLSILQKWPAVKSLPTESVGIDVVMEPKLQPSVKEKKPTKDLQSPLPSVEEDSSNRDKKTDIADLHTDSKVGIADVLSPISPDAALQSDGPLKKAKEPEESSITPTTPPSFNVGESLSRRSASPLQHPRTSPDMLDKTSPCKRGLGTITTVHKKHGSVDHLPSVKRRRSIANDFHGKPDYNKRSLSIERKPEAFKTKGDRPHKVHPSFHRNSDSKLKLEPSSKEKSGSMFFNTLRTVKDKSHVHDTQRSSDVNFSRQNGTRSHSPSVSPVGFSFDKSPVTTPPLPTAPAPVITSRHALVNNQFPTNNPNILDHKANNGDDISNALNTSRSENKPNSNLVQGSVVKPSNTSASALPTSAPKKLSLSEYRQRRQQNILHQQSKDNQAHGDTARPHTVPAATVSNPSFTR
Protein: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta) (P56932)
Organism: Rattus norvegicus (Rat)
Function: B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10556517}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
- Protein phosphatase 2 scaffold subunit A alpha
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Troponin I, cardiac muscle
- Nuclear factor NF-kappa-B p105 subunit
- Occludin
- Transcription factor p65
Sequence:
MAGAGGGGCPTGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHHVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDVTLEASRENSKPRASLKPRKVCSGGKRKKDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN
Protein: Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A) (Q5TCM9)
Organism: Homo sapiens (Human)
Function: Precursors of the cornified envelope of the stratum corneum.
Interaction partners:
- Late cornified envelope protein 4A
- Late cornified envelope protein 1A
- Late cornified envelope protein 2B
- Late cornified envelope protein 2C
- Late cornified envelope protein 1C
- Late cornified envelope protein 6A
- Late cornified envelope protein 1D
- Late cornified envelope protein 1F
- Late cornified envelope protein 1B
- Late cornified envelope protein 2D
Sequence:
MSCQQSQQQCQPPPKCTPKCPPKCTPKCPPKCPPKCPPQCSAPCPPPVSSCCGSSSGGCCSSEGGGCCLSHHRPRQSLRRRPQSSSCCGSGSGQQSGGSSCCHSSGGSGCCHSSGGCC
Protein: Transcription factor TOXE (TOX2 HC-toxin biosynthesis cluster protein TOXE) (O74205)
Organism: Cochliobolus carbonum (Maize leaf spot fungus) (Bipolaris zeicola)
Function: A pathway-specific transcription factor which co-ordinates the expression of genes involved in HC-toxin biosynthesis. Binds to the tox-box, a 10-bp motif with the consensus 5'-ATCTCNCGNA-3', which is found in the promoter of all genes involved in HC-toxin biosynthesis. Required for pathogenicity of the fungus on maize.
Subcellular location: Nucleus {ECO:0000305|PubMed:11698648}.
Interaction partners:
Sequence:
MGTTSPNSEKRQITDINERRKLQNRVAQRKYRTRQKTRMKLAEAVLNDYTYIHPTLGTIQSKKKSPLTMECDRSSASYPDLSSYAEICSETRSETQATRARQLTSQRTCFRESVDNNQADSHAQLSRCLNRQEMFYGISGETEFSEGDTRDRVECIDPNLTRGWLDMDLRSGTPNSSTVVDCGLCTVGANSQPPTRTNVQEAIETLELFEPNDQRKTENLPREPCGSCPSSSHGYSPTSGNPSTLLLTPSESLMNSVIVTSDSPLLAADDKSPGDLVISEANTHGPKEDQFSPLMTAISLGRLDIARILLQSGAPLDIPDDSGKTALHRAVGRRELHMVEALLNLGAEMLATDHEGNSLLHIAVKTNSLSITRLLLERYKSCRELKDAQLGHGCRQHGNQVHSESWIDLRNREGMTAVHLSVIFNRPEILQLLVKYSANVN
Protein: Protein turtle homolog B (Immunoglobulin superfamily member 9B) (E9PZ19)
Organism: Mus musculus (Mouse)
Function: Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development (By similarity). May mediate homophilic cell adhesion.
Subcellular location: Cell membrane {ECO:0000269|PubMed:23751499}; Single-pass type I membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:D3ZB51}; Single-pass type I membrane protein {ECO:0000255}. Postsynaptic density {ECO:0000250|UniProtKB:D3ZB51}.
Interaction partners:
- Neuroligin-2
Sequence:
MIWYVATLIASVISTRGLVAQGAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASAKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRSKHNALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLSVPPGPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVGERWEMLDDAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPLSSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEATTPIELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDPLVPTSVAALKPQLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGGRLQATGQARPPAPRPFQHGQYYGYLSSSSPGEVEPPPFYMPEVGSPLSSVMSSPPLHTEGPFGHPTIPEENGENASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFPHQLHPCDVAESLQPKACLPRGLPPAPLQVPAAYPGMLSLEAPKGWVGKSPGRGPIPAPPATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFGLDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQAEMSEITLQPPAAVSFSRKSTPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDTLDVFGQTPSPRRMGEEPLRPEPPTTLPTSG
Protein: Alpha-2-antiplasmin (Alpha-2-AP) (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Serpin F2) (P08697)
Organism: Homo sapiens (Human)
Function: Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
Subcellular location: Secreted.
Interaction partners:
- Plasminogen
- Vitamin K-dependent protein C
- Alpha-2-macroglobulin
- Fibrinogen alpha chain
- Fibronectin
- Tissue-type plasminogen activator
- Prothrombin
- Fibrinogen gamma chain
- Fibrinogen beta chain
- Carboxypeptidase B2
Sequence:
MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGVCSRDPTPEQTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK
Protein: Uncharacterized protein C691.05c (O13621)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein PYUK71.03c
- Uncharacterized protein C962.01
- Oxysterol-binding protein homolog C23B6.01c
- Vesicle-associated membrane protein-associated protein scs2
- Vesicle-associated membrane protein-associated protein scs22
- Meiotically up-regulated gene 190 protein
- Uncharacterized protein C23C11.01
- Oxysterol-binding protein homolog C2F12.05c
- SRP-independent targeting protein 3 homolog
Sequence:
MNEKLQSYEKQLTSDIVNNCDLIIEVNASSKTCQETLSSLLRELQLSHFSTAVRPGSDTSIFVFVKVQNDYLIELAHNDRTSSFLCGALDDLNHVNVNSVTDIDSSERIRLVYDKITGSKTEDSLGICPGENPYADIISIFPLHQPKFDIKWSKYWYQLLLGNKKQLDSINAEYGSQVALYFAFADFFKTGVFVLSFWGILGYYFLRPYSYIFAIGVALWGAFFIQFWRVQEHKLTNHWSTVNCQSLAKSMTEFKPQSYRVDSLLGTARPYYPQWEIIVRSTIANVPLFLISGCILLFLIAIAFIVDVTLSEVYSGPLKSIVSLLPAVVFQVLTLPFTFIYSIVAERLTKLENRRTKTDFQASLSGKMFLQNFMLSYTALFLISYIYGPFAEYFVPHYIQNRMSQSFFSVGYIAKSTFKLNPLRLRNQYIYFLTNAQVINYITILAVPQLISYVKKHYMSKPTRELHIQDIPSETVTLKRARSEAEKIEYDCYNDYKDFVLMFGFLVMFSPIYPLAPIFSLVNCVLYIRSSVYRFTKMVKKPVPCRVDSIAPWDQRLSLLSWLGCITMPSICYFYSSTTKPSDKSMVIAAVIGLLSEHLWFLLRMFISSVFPVDKTFFAPAKERQHLLAERSFSIPPVADVPTSTTTAFEEADETLSIYRTAENKKTK