wanglab/gogpt-training-data huggingface dataset:
Protein: Nuclear bridge Ish domain protein les1 (Lem-like enriched in stalks protein 1) (O94559)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Inner nuclear envelope protein involved in nuclear fission, which is achieved via local disassembly of nuclear pores within the narrow bridge that links segregating daughter nuclei. Les1 restricts the process of local nuclear envelope breakdown to the bridge midzone to prevent the leakage of material from daughter nuclei during mitosis.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:32848252}. Note=Concentrates at the stalk of each daughter nucleus during anaphase. {ECO:0000269|PubMed:32848252}.
Interaction partners:
- Nuclear membrane organization protein apq12
- Heat shock protein hsp9
- Meiotically up-regulated gene 31 protein
Sequence:
MQPRFLLHGALLALGIQLCLSIGKITGHISSIEATAADIHDAPSTTTKYVQRTVYAGREKGKIGGPADSWPQRKLDDFLQNHGVKSLDVPPIETPSQFWRKPLQYVSKVTDKCKSFYEKEKNHASHNAQKLDVWIFNSWTNSELSRWLIKNKYEVPEPGTREQLLETVFQASMGDAISTNDELESWSNNLLLSMLDQKNITVPIGASHDDLIVLARRYYDIEERKSQDKVTNITDSQPAPYMKEIIHLWSDGRLIDFLRERNIPISVLSPRETLLKEAYANRFTPRVMIASNVLDGWSSEDLLDWIWKYNKRGSIFSHVAYNSRHELIHAAKLFYMDVASEWSSSDMASLNDSLYSHPSVSKQSTWTEEELKEELESFGELVPVPFSSTKAFERLLPHLYYYLRGPAFLNRIHYWQTFLGNSLKRAFVLSQ
Protein: CD79b molecule (A0A8I5Y5U3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MATLVLSPVPCHWLMFLLLLLSGEPVPAMTKSDQPPIFQGSPCSKIWQHPRFAAKKRSSMVKFHCHTDYSGVMTWFRQKGNQRPQELFPEDGHISQTRNGSVYTLTLQNIQYEDNGIYFCQQKCNSTEPDVTDGCGTELLVLGFSTLDQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKVPTGTGEWEELWKAGRLAQGRQDLGGVPIFSDSVAAHPAPSLSIGSLFVHSFGLGDSFPLPLPHPDPHPWPIRGQRWRTLTL
Protein: NAD(P)H-hydrate epimerase (EC 5.1.99.6) (Meiotically up-regulated gene 182 protein) (NAD(P)HX epimerase) (O13725)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity). May have a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03159, ECO:0000269|PubMed:16823372}. Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03159}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable pyridoxamine 5'-phosphate oxidase
- ATP-dependent
- Zinc finger chaperone zpr1
- Meiotically up-regulated gene 65 protein
- Putative ATP-dependent RNA helicase ste13
- mRNA-decapping enzyme subunit 1
- mRNA decapping complex subunit 2
- Deadenylation-dependent mRNA-decapping factor pdc2
- Putative malic acid transport protein
Sequence:
MSISCLSASAAKALDAELMSAGAFSIDQLMELAGLSVSQAVYREYPPSQYSQVLICCGPGNNGGDGLVAARHLWQYGYKPTVYYPKPSSPELYKRLCKQLDDLDIPVVKSHDSNHFSQLLRDSKLVVDSIFGFSFKGPVRDPFGSILAAIVESKIKVLSVDAPSSWEIDEGPQKEGPLKDFDPDTLISLTAPKPCSKFYKGKHYLGGRFVSKVITKKFNLSLPPYPGIDQVVDITNKPLSMV
Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C) (P25455)
Organism: Drosophila melanogaster (Fruit fly)
Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Interaction partners:
- Guanine nucleotide-binding protein subunit alpha
- Diacylglycerol kinase
- Guanine nucleotide-binding protein subunit alpha
- Diacylglycerol kinase
- Guanine nucleotide-binding protein subunit gamma-e
- Kinase
- Kinase
- Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform E
- Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl
- Guanine nucleotide-binding protein subunit beta-2
Sequence:
MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDTLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLYKYLTQRSEVERLFDSIVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCNPRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMDLPPPAMLRRKIIIKNKKKHHHHHHHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPPLQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCYEMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTVSITVLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVVKDYVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSFVFVQVGGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEIPACPLDLGDSSEESAAADAGEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQTKQLKASLDKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVASSVVERGVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPHHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT
Protein: Metastasis associated 1 (H0Y4T7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
QIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLLMPSRGTYLGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
Protein: Asialoglycoprotein receptor 1 (ASGP-R 1) (ASGPR 1) (Hepatic lectin 1) (HL-1) (mHL-1) (P34927)
Organism: Mus musculus (Mouse)
Function: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- Asialoglycoprotein receptor 2
- Thyroglobulin
Sequence:
MTKDYQDFQHLDNDNDHHQLRRGPPPTPRLLQRLCSGSRLLLLSSSLSILLLVVVCVITSQNSQLREDLLALRQNFSNLTVSTEDQVKALSTQGSSVGRKMKLVESKLEKQQKDLTEDHSSLLLHVKQLVSDVRSLSCQMAAFRGNGSERTCCPINWVEYEGSCYWFSSSVRPWTEADKYCQLENAHLVVVTSRDEQNFLQRHMGPLNTWIGLTDQNGPWKWVDGTDYETGFQNWRPEQPDNWYGHGLGGGEDCAHFTTDGRWNDDVCRRPYRWVCETKLDKAN
Protein: Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form] (P23563)
Organism: Sus scrofa (Pig)
Function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6 (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted {ECO:0000250}.; SUBCELLULAR LOCATION: [C-domain 1]: Secreted {ECO:0000250}.; SUBCELLULAR LOCATION: [C-domain 2]: Secreted {ECO:0000250}.
Interaction partners:
- Interleukin-1 beta
- Multifunctional fusion protein
- Multifunctional fusion protein
- Multifunctional fusion protein
- Multifunctional fusion protein
- Multifunctional fusion protein
- Multifunctional fusion protein
- Multifunctional fusion protein
- Multifunctional fusion protein
- Interleukin-8
Sequence:
MSTESMIRDVELAEEALAKKAGGPQGSRRCLCLSLFSFLLVAGATTLFCLLHFEVIGPQKEEFPAGPLSINPLAQGLRSSSQTSDKPVAHVVANVKAEGQLQWQSGYANALLANGVKLKDNQLVVPTDGLYLIYSQVLFRGQGCPSTNVFLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKDDRLSAEINLPDYLDFAESGQVYFGIIAL
Protein: Caprin-1a isoform X1 (Cell cycle-associated protein 1a) (E7FDQ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- GTPase activating protein
- GTPase-activating protein
- Uncharacterized protein LOC406683
Sequence:
MPSVTAGDNAVHSSSPDLGSAPSEALKQVLVVIDKKVRNMEKRKSKLDDYQTRKDKGERLNQDQLEALSKAPEVAHNLDFARELQKSFLALNVEIQKTVKKATRREQLKREEAERKRLKAVLEIQYLLEQLGEENVRQELTQSTGEASLLTEAELMGLDEFYKLIGPERDSSVRLAEQFDEASVHLWELLEGRDKAVAGTTYKALKETLDKMLLSGYFDRAPTHQNGVCEEETGATVVESSESEEHPAEPEGAAQEYSETEVEATEFVNRQFIPEAAYSSSEKEQGAEWNTSSQVVSVLQQPQQPPAAMSPTLMSSDAHTLNAVLPPPPATDPVVRKQAVQDLMAQMQGTFNFMQDSMLEFEGPPLDPAIVSAQPMKPAQMVCPPESRLPQHNALSVQPEPTQVPMVSASTPPLYQPAHTSEPRPQTDTIDPLQVSMPLPSEQPPTPSSQPQVFQPKPLHSGINVNAAPFQSMQAVFNMNAPVPPTNEMDSPKISSQYQSSYGQGFSTQAALPAEQQEMPQEALQSVGSFQSQDQGITSAGGHQSAPQQPSGQGTGFGRPGQSFYSNRAMPRTGPRNPRGSLNGYRGPSNGFRGGYDGYRAPFPNTPNTGYGQTQFSTPRDYSNNTYQREGYQQSFKRGAAQGPRGCSRGRGGSYRSSRGMGPMAAQQTS
Protein: Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (DppIV) (Q2UH35)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Subcellular location: Secreted {ECO:0000269|PubMed:9835566}.
Interaction partners:
- Dipeptidyl-peptidase 5
- Extracellular metalloproteinase NpI
- Neutral protease 2
- Neutral protease 2
- Neutral protease 2 homolog AO090001000135
- tripeptidyl-peptidase II
- tripeptidyl-peptidase II
- Leucine aminopeptidase 1
Sequence:
MKYSKLLLLLVSVVQALDVPRKPHAPTGEGSKRLTFNETVVKQAITPTSRSVQWLSGAEDGSYVYAAEDGSLTIENIVTNESRTLIPADKIPTGKEAFNYWIHPDLSSVLWASNHTKQYRHSFFADYYVQDVESLKSVPLMPDQEGDIQYAQWSPVGNTIAFVRENDLYVWDNGTVTRITDDGGPDMFHGVPDWIYEEEILGDRYALWFSPDGEYLAYLSFNETGVPTYTVQYYMDNQEIAPAYPWELKIRYPKVSQTNPTVTLSLLNIASKEVKQAPIDAFESTDLIIGEVAWLTDTHTTVAAKAFNRVQDQQKVVAVDTASNKATVISDRDGTDGWLDNLLSMKYIGPIKPSDKDAYYIDISDHSGWAHLYLFPVSGGEPIPLTKGDWEVTSILSIDQERQLVYYLSTQHHSTERHLYSVSYSTFAVTPLVDDTVAAYWSASFSANSGYYILTYGGPDVPYQELYTTNSTKPLRTITDNAKVLEQIKDYALPNITYFELPLPSGETLNVMQRLPPGFSPDKKYPILFTPYGGPGAQEVTKRWQALNFKAYVASDSELEYVTWTVDNRGTGFKGRKFRSAVTRQLGLLEAEDQIYAAQQAANIPWIDADHIGIWGWSFGGYLTSKVLEKDSGAFTLGVITAPVSDWRFYDSMYTERYMKTLSTNEEGYETSAVRKTDGFKNVEGGFLIQHGTGDDNVHFQNSAALVDLLMGDGVSPEKLHSQWFTDSDHGISYHGGGVFLYKQLARKLYQEKNRQTQVLMHQWTKKDLEE
Protein: Transcription factor SOX-17 (Q9H6I2)
Organism: Homo sapiens (Human)
Function: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal development of the definitive gut endoderm. Required for normal looping of the embryonic heart tube. Plays an important role in embryonic and postnatal vascular development, including development of arteries. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX18. Required for the generation and maintenance of fetal hematopoietic stem cells, and for fetal hematopoiesis. Probable transcriptional activator in the premeiotic germ cells.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
- POU domain, class 5, transcription factor 1
- Catenin beta-1
- Lymphoid enhancer-binding factor 1
- Transcription factor 7-like 1
- Hepatocyte nuclear factor 3-beta
- Transcription factor 7-like 2
- Transcription factor 7
- Transcription factor GATA-4
- Homeobox protein NANOG
- Transcription factor GATA-6
Sequence:
MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPLPTPDTSPLDGVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPSQPAELLGEVDRTEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
Protein: Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats domain-containing protein (Q38A09)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Uncharacterized protein
- Cell division control protein, putative
- Pre-mRNA-splicing factor SLU7
- Small nuclear ribonucleoprotein SmD1
- Pre-mRNA-processing factor 19
- Uncharacterized protein
- G10 protein
- Sm protein B
- Uncharacterized protein
- U5 small nuclear ribonucleoprotein component, putative
Sequence:
MKRNRNHNDQMGPAAAALRRRSVFRDARASSTQLTDAQLIAGALEMQRSIGPSNTSTTVVINSPEELALYRQKTRAELEERVKRGYTFLGNWVKYARWEAQQKDYERMRSILERAVKFHGANPVLWRDYAELEEEGGFINHARAVWERGVTALPSATDLWLKYIVLEQAAGQDGKVRDLFNRWVSGPTPPACAWELFALFEAQQRRAENCRDILRRYVEAHGTVECWIFYGSAELNVLKNADRAAMVYACAMESLPNEYINGEKDCRIPLAWADALAAALKFDEARELYHRLLKECTSVKALDAIFTAYKRFERLYGSAENHETMTSVIARAMYQHRIAHNPRDFDAYVAQFLLFRDATQGDNASVCAGHAVNVGSKGGAWEEALQCLTAAAGIRIDGEKDAVLAQHHAVVVMAYARLVEERGDVAAARSALAKCIRHFPFKTACCPRLWIEAAALEERHGEFVQAQKLLAASLNISPCPEVFDAALRLESNACAAGEVSAESCVQRSRAIYESAIKQFPQNFALWEGYAKLEEKERQFHRSDALRAACIRSFSAVARSVVSLSERYEVLEKVDQAWARRLALKRRLLRSARKKTCGGLSESAEVEELNFSLRQLYQELLDSVWDEYIYEALRWRGKNASTVGVLSPPPLRLPEVLTPATARWAEAVSAVTNFVVSSTTADGRPEDSSVEWMRTTFRKRLERYRPKLLQEFGGLDNNASFEAIQQSKRWVEFLLSPNGTEWRRFEAAHGTSDTLEAAKECTQPTARRTRLFVKKKA
Protein: Uncharacterized protein (Q38BN2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNEDDILFAQPQVSSSRSGEGYLMDVTTTAITSEPSKSEASKWQGSPLDSVSAESKAADVKGETSDPVQLWGDTQQSKNENGDWDDGDDFGDFVESAPCVSEASARPSAAVGAHSEKVDEWGEAVEAATASNVAVQGIEKEEPKNEATSKNVGITGSAVAWGRCDTTSGGISHKDPLSITFNGTSSGNTFGAQTFTSNNTYGSANNNSPGVDDDEWMDFQENGPTTVQPSKPLSATSTSASFPMDCGLAGSLSLLSGGGNFEFEQDFDTALLAKQLFSFTGCTVDTSAGANRKMDYHTNTWALEGTSNQRESYSAGDIVTAMMEAFFFRRRKIDKNVAGTFQGVGTLFVSHISEMAARKLRNSTQSLQNMNLGATMGGKMEERWDVIGDVDPVTAVRIAELHTIRFFSNTDSFLLQPMEAQTWQVAKGPIPICDVIAKVKALNAERQKQQQYQSVTDVTADLWTVHPLLPTPHIGGSVSPAPSLQLPF
Protein: Nuclear pore complex protein (A1YK59)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|RuleBase:RU365072}. Nucleus membrane {ECO:0000256|RuleBase:RU365072}.
Interaction partners:
Sequence:
MADSPFPRSSRSGLLRTTLNSSMAPQNLSHSLLILEKSNAEQNERSLMEDTGDDLDRGKSRMDVLFPQFFDVLQAQGNGQEAFEVIQSLTQVCRGVVEQLELEIDHGMGGEQGARQRESMLTWLRXXINTWRLLHALFYDRILLQTDRQADDEMQDGPTLGGSEKEVIQQLYALNATLREYQLVVDWLEACYDRGEQQNPLHAHDRMMAWENTLFQLENLQGAAFGKGHKIVTRLDPDAPVREKRPLHALDEEDNLRLSRAIFELIRXXXVDDGLKLCKHFGQTWRAAILEGWRLHEDPNFEQNVSVLHEKLPIEGNPRRDIWKRCAWMLADSKNYDEYSRATAGVFSGHLGSLKTLLHSNWHDLLWAHLKVQIDIRVESEIRGCCLKNYQPMPDDYWNGRMTMEQIFEELNVAKDASVRDFAQSQLGIIQRHLILDTCGELIQHMVRWVEKDTSQQSPHQLRFMAHIVLFLRQIGRVEQERQAEKIVAAYVEALIARGEPQLIAYYTASLSNPLQVQLYSRFLEQVEQKRPRELAVDAALQAGLDVEQITRVTVQNIRLAHQPLGEFGEPQSGEISAIDQRKISALEWLIHLPEQRGELLWQANAMIRTYLASSKVECMRQTFRMVPADIVQQLVSLYGSVDNIPPREECCLKEYLCYKAYLSGVDSFVEWNRLQQNRPKKPQTSHAASSQDNFTERMASERKEQAHRSEVVRWEHKVKEQAKQTIELLYNVLMFPDKGWLVDPFIAKLPENAVQLNWDHRLLQMEKLRSICIPEIALFLNEVMFKSGDFAGCVRLADEISSENRQLYKVYTKHKLAELLAKIADAFLELLNSKLDPWGYPITT
Protein: Uncharacterized protein YjiJ (P39381)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MPSSTHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAEGSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWLPPFILVLLIRVLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLAGLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAILYGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPCLTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLSNGTSALASATLCGAAALFIAALISTVQLFKLQVVTS
Protein: Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (Vesicular-fusion protein Sec18) (OsSec18) (Q0DGP6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity). Involved in spikelet development. Regulates protein storage vacuole (PSV) morphology in endosperm cells. Forms a quaternary complex with the two glutelin zipcode RNA-binding proteins RBP-L and RBP-P, and the membrane trafficking factor RAB5A. This quaternay complex carries glutelin mRNAs for active transport on endosomes to the cortical endoplasmic reticulum membrane, and enables endosome-mediated glutelin mRNA transport in endosperm cells.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P54351}.
Interaction partners:
Sequence:
MAGRNYHGYGGGGGGGMSMVVASTPGQELALTNCAYVSSADIRRFPNALALVGDAFVFTLRAHDAVSAGSIALNAIQRRQTKVSAGDSITVSSFAPPDDFKLALLTLELEYTKARTNRNEELDAVVLAQQLRRRFLDQVMTSGQRVPFEFCGTNYIFTVNQALLDGQENSTPLDRGFLSSDTYIIFEAAPNSGIKVVNQKEAASSKLFKHKEFNLEKLGIGGLSAEFTDIFRRAFASRVFPPHVVNKLGIKHVKGILLYGPPGTGKTLMARQIGKLLNGNEPKIVNGPEVLSKFVGETEKNVRDLFADAENDQKTRGDQSDLHVIIFDEIDAICKSRGSTRDGTGVHDSIVNQLLTKIDGVEALNNVLLIGMTNRKDLLDEALLRPGRLEVHIEINLPDENGRLQILQIHTNKMKESSFLSPNVNLQELAARTKNYSGAELEGVVKSAVSYALNRQISMDDLTKPLDEESIKVTMDDFVNALHEITPAFGASTDDLERCRLRGMVDCGKAHRHLYERGMLLVEQVKVSKGSPLVTCLLEGPAGSGKSALAATVGIDSDFAYVKIISAETMIGFSESSKCAQICKVFEDAYKSQFGIIILDDIERLLEYVAIGPRFSNIISQTLLVLLKRVPPKGKNLLVIGTTSEVGFLESIGMCDVFSVTYHVPKLKKEDATKVLRHLNVFDEADIDAAAEALDDMPIKKLYTLVEMAAQGPSGGSAEAVYGGEEKIDINHFFSILSDIIRY
Protein: Transcription factor TGAL5 (bZIP transcription factor 41) (OsbZIP41) (Q6F2N0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional regulator involved in defense response.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- BTB/POZ domain and ankyrin repeat-containing protein NPR1
- BTB/POZ domain and ankyrin repeat-containing protein NPR3
- BTB/POZ domain and ankyrin repeat-containing protein NPR2
Sequence:
MIQSDAYTESAGYLAARPPTLEIFPSWPMSHLQEPYSNSQSVGSTTDSSSAQNTMSQAELVSPASMRSDSGQEQQQQEVLMVTIDDYNYKQGLGAAIATAPSFQQHAGGLDMRKHGSTRKDGKLLDAKTERRLAQNREAARKSRLRKKAYVQQLETSRIRLQQIEQELQRARSQGLFPGGCSAPGDMSSGAVMFDMDYTRWIDDDSKCMAELQGALQAQLPDGNLGAIVEECMRHYDELFHLRAVLASSDVFHLMTGMWAAPAERCFLWMAGFRPSEILKMLIPQLDPLTEQQLMGMCSLQQSSEQTEEALAQGLHQLHQSLADAVGGGPLNDGADVANYTGLMALALGRLENLESFYRQADNLRQETLHHMRRILTTRQTARCFLSIGEYNRRLRALSSLWASRPRENFIATENVSPTGTEFQVIQQSQQNQFSGF
Protein: Cyclin-dependent kinase-like 5 (A0A8I6A725)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRSQSTKGGALQTHHRSNSKDIQNLSVGLPRAEEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGIDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHSDQLKEKEKQGFFRSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGLHQESF
Protein: Phakinin (49 kDa cytoskeletal protein) (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 47) (CP47) (Lens fiber cell beaded filament protein CP 49) (CP49) (Lens intermediate filament-like light) (LIFL-L) (Q6NVD9)
Organism: Mus musculus (Mouse)
Function: Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. Plays a role in maintenance of retinal lens optical clarity.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q28177}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q28177}; Cytoplasmic side {ECO:0000250|UniProtKB:Q28177}. Cytoplasm {ECO:0000269|PubMed:27559293}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q28177}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q28177}. Note=Expressed primarily at the plasma membrane in peripheral lens fiber cells, however also localizes to the cytoplasm in mature lens fiber cells. {ECO:0000250|UniProtKB:Q28177}.
Interaction partners:
- Heat shock factor protein 4
- Beta-crystallin B1
- Filensin
- Gamma-crystallin S
- Beta-crystallin B2
- Gap junction alpha-8 protein
- Gamma-crystallin D
- Lens fiber major intrinsic protein
- Beta-crystallin B3
- Alpha-crystallin A chain
Sequence:
MSKRRVAADLPSGTNSSMPVQRHRVSSLRGTHSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLANVPAPGPERDHTTVEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKSSGGWDALRASWASSYQQVGEAVLENARLLLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGFLSRSYEEDVKVLYKQLAGSELEQADVPMGTGLDDVLETIRVQWERDVEKNRAEAGALLQAKQQTEVVHVSQTQEEKLAAALSVELHDTSRQVQSLQAETESLRALKRGLENSLHDAQHWHDMELQNLGAVVGRLEAELAEIRSETEQQQQERAHLLACKSQLQKDVASYHALLDREENN