wanglab/gogpt-training-data huggingface dataset:
Protein: Reduced viability upon starvation protein 167 (P39743)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of a cytoskeletal structure that is required for the formation of endocytic vesicles at the plasma membrane level. Could be implicated in cytoskeletal reorganization in response to environmental stresses and could act in the budding site selection mechanism.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Actin-binding protein
- Proline-rich protein LAS17
- Reduced viability upon starvation protein 161
- Actin
- Proline-rich protein HUA1
- Protein BZZ1
- Verprolin
- Clathrin heavy chain
- Actin cytoskeleton-regulatory complex protein SLA1
- Myosin tail region-interacting protein MTI1
Sequence:
MSFKGFTKAVSRAPQSFRQKFKMGEQTEDPVYEDAERRFQELEQETKKLSEESKRYSTAVNGMLTHQIGFAKSMEEIFKPISGKMSDPNATIPEDNPQGIEASEQYRAIVAELQETLKPDLALVEEKIVTPCQELLKIITYIRKMATKRNHKKLDLDRHLNTYNKHEKKKEPTAKDEERLYKAQAQVEVAQQEYDYYNDLLKTQLPILFSLEAEFVKPLFVSFYFMQLNIFYTLYNRLQDMKIPYFDLNSDIVESYIAKKGNVEEQTDALTITHFKLGYSKAKLEMTRRKYGVATAEGSPVSGASSGVGYGAGYDPATATSPTPTGYGYGAAAPSYAAQPAAQYGTAAAVGTAAAVGTAAGAAAGAVPGTYPQYAAAQSPPLTGLGFQQSPQQQQGPPPAYSNPLTSPVAGTPAAAVAAAPGVETVTALYDYQAQAAGDLSFPAGAVIEIVQRTPDVNEWWTGRYNGQQGVFPGNYVQLNKN
Protein: Phosphoprotein p93 (Q09933)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in sister chromatid separation.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:7628693}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:7628693}. Note=Spindle pole body during metaphase and spindle microtubules during anaphase.
Interaction partners:
- Microtubule integrity protein mal3
- Kinesin-like protein 5
- Microtubule protein alp7
- Inner kinetochore subunit mis6
- Kinetochore protein ndc80
- Kinetochore protein nuf2
- Kinesin-like protein 6
- Tubulin alpha-2 chain
- Tubulin beta chain
- Kinesin-like protein cut7
Sequence:
MELDDFNSRILSQIFDKSWKVRFEAYESLLHALNRALDDSDVCFQPWIHDPALWKQGLCDSNVPTQEHAVKSLRCFLDKSRQKGVNSAKSFVVAPLLEKCLPSPRQSIRDASHQALLILAKSDALDYVLEGLFSAARVKHPKQAVASIKELNSLLENFGIPALSPIPFYKLIPTLFAQSDKNIRQEASNLSITLYAWVGNAFKTHVFPQLKQIQVSDLEASFQNVTSRTTTGGHISNSLNTQEVVLPSFSSNAKPKPHLSSKSSSQGNTLQRSTSSFSTPNRKVSQPSDFSASPSRSIVSPAKNIVGSTPVDVLSKLTPEFHTALSSPKWKDRKEALESMVPVCSNPVYQEGDYSELLRVIAKSLKDANVVVVGVAALLLTHIAKALRKGFLPYTGIVLPSLFDRFKERKSSLVHSLLDAANAIFESCGLNDIMDETLEFLKHKNPQVKTETLRWLNRCLQLTDVCPPRASLETLCSLCVTLINDTFEPVRMATTNVLATLVQIFSQPVLSKYIVGLDPKKLPKILELSKDITVNAHPNQPSRPRLPRVASPLKTSPVKLAVTPQAPSPLPSSNPSQASLTEESLSTRSSPTKPSTTSLRSQSLVNRFASSTLKAPSSSSKGVSNAASSKQSFPSSPSISKKLETSRLSTKKLPGSTMKAASALKEYPQQQSMKSGGEKQDNLVTITMSEKVELDLLREEKAIRQVQEAEDALERERLFREINDLQIQNAEMKEQVYEKESTISQKEVEITSLRNEKDRLSTRLQQVLLELEKQHETNEEAMDIDLKVPESGAIGRVTTRATATTAMDESGNAGMVSSGIHSVSTKPSSYGTRRSLAGSMLQKPTQFSRPSFMFSPEARDNWRESHDLSSHLWEQIQRMKKA
Protein: Prothymosin alpha (Q8TBK9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNANEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEGGDEDEEAESATGKRAAEDDEDDDVDTKKQKTDEDD
Protein: Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)] (Q9P7R0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03143}.
Interaction partners:
- Chorismate synthase
- Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited
- Chorismate mutase
- Putative phospho-2-dehydro-3-deoxyheptonate aldolase
- Multifunctional tryptophan biosynthesis protein
- Putative prephenate dehydratase
- Tryptophan synthase
- Anthranilate phosphoribosyltransferase
- Probable prephenate dehydrogenase [NADP
- Putative aminodeoxychorismate synthase
Sequence:
MSNESNIITVPILGKDTVRVGFGIHQYICTEILENFKSSTYVVITDSNIAPLYLEKIESTFNKSIKDAKAEARLLTYVIPPGESSKCRAMKAEIEDWLLTQSCTRDTILIAMGGGVIGDLVGYVAASFMRGIRFIQMPTTLLAMVDSSIGGKTGIDTPLGKNLVGAFWQPLRVYVDMVFLHTLPPRQVINGLSEIIKTAAMWNENDFQLLENNSAVLLDALNKPSVPGEYKFDSIKPLLQKIILSSIRTKCEVVTLDEHEGGLRNLLNFGHSIGHAYEAILYPQILHGECVAIGMVKEAELARYLGILKPNAVGRLTKCLVSYNLPISVNDPKVKKYASFKHCPVEKLIEYMAVDKKNQGSKKRIVILKAIGETYEKHATVVSDDDIRFILSRDVKVDEFTKSSWDVVVTPPGSKSISNRALVLAAMGNGTCRLTNMLHSDDTQFMMSALESLGAATFSWEDGGETLVVKGNGGKLAVPKEELYLGNAGTAARFLTGIAALVSSKDGAKVVLTGNHRMKVRPIGPLVDALRANGCEINYLEKQGSLPLDLSSKNGLKGGIIELAATVSSQYVSSILMCAPYASQPVTLKLVGGKPISQLYIDMTIAMMASFGVNVTKSTTEENTYNIPCGKYQNPPHYEIESDASSATYPLAIAAITGTKCTVPNIGSASLQGDARFACDVLRPMGCTVEQTATSTTVQGPPKGTLKPLESIDMETMTDAFLTASVVAAVACNVSEGDPVTRITGIANQRVKECNRIAAMVHELAKFGVRTGELEDGIYIFGKNYKELKKPEEGIYTYDDHRIAMSFSVLSLICPSRTLIIDKACVEKTWPYWWDVLHQSFGVKLTGATSVASDPLKGSISKNASIILIGMRGAGKTTIGKIIAKQLNFKFLDLDELLEDYLEMPIAEVIFRMGWDAFRLEEHKVLRKFITEHPEGYVAASGGGVIEMDESRNLLSNFVKEGGIVLHVHRNLEHIKSYLSEDQTRPTYKDQESIDDVYKRRHVWYRECRSHYFISPVLSNQVIDEKIQYSMSRFLDVVTGSSQVLQKFKTKKRSTFLTLNYPRIEDALPTLRDVTVGCDAIEVRVDYLKDPKSSNGISSLDFVAEQISLLRCSTTLPIIFTIRTISQGGLFPNDKEEEAKELMLSAMRYGCDFVDVELGWSSETINILYQHKGYTKLIMSWHDLSGTWSWARPHEWMQKVELASSYADVIKLVGMANNLNDNLELEEFRTRITNSMDIPLILFNMGRFGQLSRILNKFMTPVTHPLLPSKAAPGQLTVKQLNEARVLIGEILPEKFFLFGKPIKHSRSPILHSTAYELLGLPHTYEAFETDTVDEVQKVLNLPDFGGANVTIPYKLSVMKFMDELSDEARFFGAVNTIIPIRIGDKLVLRGDNTDWRGIYDTFANALDGVSLRDTNGLVIGAGGTSRAAIYSLHRLGVSRIYLLNRTLANSYRVQDVFPPDYNIHIIDSDNIPSEELSSVTLSAVVSTIPADIELPEKVASVIKALLANKADGGVFLDMAYKPLHTPLMAVASDLEWKCCNGLEALVRQGLASFHLWTGMTAPFDAVYQKVIE
Protein: Platelet glycoprotein 4 (Glycoprotein IIIb) (PAS IV) (PAS-4) (Platelet glycoprotein IV) (E7EU05)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
Interaction partners:
Sequence:
MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLWGYRDPFLSLVPYPVTTTVGLFYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFMISY
Protein: Hepcidin (Q99MH3)
Organism: Rattus norvegicus (Rat)
Function: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.
Subcellular location: Secreted.
Interaction partners:
- Ferroportin
- Solute carrier family 40 protein
- Hemojuvelin
- Natural resistance-associated macrophage protein 2
- Hereditary hemochromatosis protein homolog
- Transferrin receptor protein 2
- Neutrophil gelatinase-associated lipocalin
- Transmembrane protease serine 6
- Transferrin receptor protein 1
- Plasma membrane ascorbate-dependent reductase CYBRD1
Sequence:
MALSTRIQAACLLLLLLASLSSGAYLRQQTRQTTALQPWHGAESKTDDSALLMLKRRKRDTNFPICLFCCKCCKNSSCGLCCIT
Protein: Prohibitin (E9PCW0)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU366048}.
Interaction partners:
Sequence:
MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEG
Protein: DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (ABC27) (DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide) (P20434)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. RNA polymerase complexes are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
Subcellular location: Nucleus.
Interaction partners:
- Transcription elongation factor SPT4
- DNA-directed RNA polymerase II subunit RPB3
- Transcription elongation factor S-II
- DNA-directed RNA polymerase III subunit RPC7
- DNA-directed RNA polymerase I subunit RPA43
- Transcription elongation factor SPT5
- DNA-directed RNA polymerase I subunit RPA135
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I and III subunit RPAC2
- DNA-directed RNA polymerase I subunit RPA49
Sequence:
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
Protein: Probable inactive receptor-like kinase BSK12 (Brassinosteroid-signaling kinase 12) (Protein SHORT SUSPENSOR) (Q7XJT7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable inactive protein kinase that activates the YODA MAP kinase cascade, which regulates the asymmetric first division and embryo polarity, by promoting the elongation of the zygote and the development of its basal daughter cell into the extra-embryonic suspensor. Acts as an adapter at the plasma membrane, possibly by recruiting and binding an activator.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19286558}; Lipid-anchor {ECO:0000269|PubMed:19286558}.
Interaction partners:
- Serine/threonine-protein phosphatase BSU1
- Protein BRASSINOSTEROID INSENSITIVE 1
- BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1
- Shaggy-related protein kinase eta
- Protein BRASSINAZOLE-RESISTANT 1
- Putative acyl-activating enzyme 19
- Auxin-responsive GH3 family protein
- Auxin-responsive GH3 family protein
- Auxin-responsive GH3 family protein
- Auxin-responsive GH3 family protein
Sequence:
MGCCYSLSSTVDPVQDHTTDASSEPRNGGGEDPPLTKFSFSALKTATNHFSPENIVSDQTSDVVFKGRLQNGGFVAIKRFNNMAWSDPKLFLEEAQRVGKLRHKRLVNLIGYCCDGDKRFLVADFMANDTLAKRLFQRKYQTMDWSIRLRVAYFVAEALDYCNTAGFASYNNLSAYKVLFDEDGDACLSCFGLMKEINNDQITTGSVNPENVIYRFGTVLVNLLSGKQIPPSHAPEMIHRKNVFKLMDPYLKGKFSIDEANVVYKLASQCLKYEGQESPNTKEIVATLETLQTRTEAPSYEVVEMTNQEKDASSSSNLSPLGEACLRMDLASIHSILVLAGYDDDKDIIELSFEEWIQEVKELQDVRRNGDRAFVEQDFKTAIACYSQFVEERSLVYPSVYARRSLSYLFCDEPEKALLDGMHAQGVFPDWPTAFYLQSVALAKLDMNTDSADTLKEAALLEVKK
Protein: Uncharacterized protein (Q583J5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLSPSGASAAELDEALNQYISAIHPTVCPHLTPRHLLRVIPAQPLPVRTVWRRAISMETVPSDMSFEAFKSALMPLVPLFLSLSSTTLGEDGDEGPLVRWQPWVSDGWRNEQERTREQCGDGVISELSGVVPTYFVSYALLKEQTRLGQLSVATLHTLERKELVGGSVPPVLEWSEDHSVVRLSNEVIASSSSTRTANSFYSLQSQPEVLRRAVNILALLLPTFKASVGEVRAVYKLNFITPGGLRHSAITHEFAIRFPDALALVDHPDVQFVIDRDSEGCVMLHSTFLHTSRGAANVLYMCTSVGHPLSISAHGVDTNEGAGCLDRYYLRVDLPYAPRCGDEVVLQAICSATVTGLYCVQQPDKDRFSLEIATAQGAVIVFDSTISLLCRLSTAGAPCCGFPAEIVTLLASPNIVKLIHAAPTVCTGNQGVYGNVLDGLPLLYAHLKTDFQCVCTFHQLALFVGIPTTETERPGQYSLLSNRLITCHGGVALPHVRPALLAAVCASRLIALHLADGHEFDRALLQQLLRDAVEGSNALVMRNLQLRLKRYGMEPHGTCTKHSCEALLQEFLVVYGPEVCFVDKFDDFLSRAASSTEIARTVGKNRSEEDDGEYIRELLLDQPTSTVERDEEDMDVEHDVQGELSKCCKQNVGSGDSEVTKRSEGEQDNMEEAYNFLFDCSGAGATDKGSNIPPSHRSSNHMNCSRGNEQSERSTVFVLPLPNLKGHHMTSRNVRWTLPPSFSRTNVRGTTTTKAEQSVKTIHGASTRSLLPEQRDPTNWHIDKSDEHTEGIASEGALIERLTQEVLCATSSSKTNKRRLPACSSDRLISE
Protein: Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) (P53598)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit (By similarity).
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03222, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}.
Interaction partners:
- 2-oxoglutarate dehydrogenase, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase cytochrome b subunit
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Mitochondrial inner membrane protein SHH3
- Succinate dehydrogenase flavoprotein subunit 2, mitochondrial
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Sequence:
MLRSTVSKASLKICRHFHRESIPYDKTIKNLLLPKDTKVIFQGFTGKQGTFHASISQEYGTNVVGGTNPKKAGQTHLGQPVFASVKDAIKETGATASAIFVPPPIAAAAIKESIEAEIPLAVCITEGIPQHDMLYIAEMLQTQDKTRLVGPNCPGIINPATKVRIGIQPPKIFQAGKIGIISRSGTLTYEAVQQTTKTDLGQSLVIGMGGDAFPGTDFIDALKLFLEDETTEGIIMLGEIGGKAEIEAAQFLKEYNFSRSKPMPVASFIAGTVAGQMKGVRMGHSGAIVEGSGTDAESKKQALRDVGVAVVESPGYLGQALLDQFAKFK
Protein: Phospholipid/glycerol acyltransferase domain-containing protein (Q54IG1)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MEPLTTSTSTTSSSSSSSSSSSSSSSSSPPKQRIPKKRYLHDYGRYSSEFNSGFRLWLEKWNRRSISISLILIVLVVLTLLFPVLAIVALALDLYHYKRRRGLNYVRILTFFESYLFIELIALISTFLIYFIHLLSLLVVSDPGKARFFRWNYWYQSWWGGEMLFGWSCYLLGIDVQIEVAGDVNSSFIAHYYDKGFKKRLADSLGIGPKIIFSRHASFADTLVPQGIFSLFYHMRYIVKKELLWDPALDVSGSRTPNFFLFRDAGTDGMEVEIEAIKSMVSDFKPTEPDVTCIWPEGTRFSKSKREKVLESFKKKNDTKNYELASNLKHTLLPRVGGVLSLLEANPCGDILFCSHFGMEASSDFGQMMNGELCNRVVKIKFEQIKYKDIPKTKQERIDWLLRKWVDIDQWIDQQDKLYKNEKLSLKKKKSE
Protein: Ent-cassadiene hydroxylase (EC 1.14.14.69) (Cytochrome P450 71Z7) (Q6YV88)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Enzyme of the diterpenoid metabolism involved in the biosynthesis of antibacterial oryzalides such as phytocassane. Catalyzes the hydroxylation of ent-cassa-12,15-diene to form ent-3beta-hydroxycassa-12,15-dien-2-one.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable 5'-adenylylsulfate reductase 1, chloroplastic
- Nitrate reductase
- Nitrate reductase
- Nitrate reductase 1
- 4-coumarate--CoA ligase
Sequence:
MEDNKLILALGLSVLFVLLSKLVSSAMKPRLNLPPGPWTLPLIGSLHHLVMKSPQIHRSLRALSEKHGPIMQLWMGEVPAVIVSSPAVAEEVLKHQDLRFADRHLTATIEEVSFGGRDVTFAPYSERWRHLRKICMQELLTAARVRSFQGVREREVARLVRELAADAGAGGDAGVNLNERISKLANDIVMVSSVGGRCSHRDEFLDALEVAKKQITWLSVADLFPSSKLARMVAVAPRKGLASRKRMELVIRRIIQERKDQLMDDSAAGAGEAAAGKDCFLDVLLRLQKEGGTPVPVTDEIIVVLLFDMFTGASETSPTVLIWILAELMRCPRVMAKAQAEVRQAAVGKTRITENDIVGLSYLKMVIKEALRLHSPAPLLNPRKCRETTQVMGYDIPKGTSVFVNMWAICRDPNYWEDPEEFKPERFENNCVDFKGNNFEFLPFGSGRRICPGINLGLANLELALASLLYHFDWKLPNGMLPKDLDMQETPGIVAAKLTTLNMCPVTQIAPSSAEDAS
Protein: Putative MO25-like protein At4g17270 (Q9M0M4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- CBL-interacting serine/threonine-protein kinase 19
- Putative beta-glucosidase 5
- non-specific serine/threonine protein kinase
- Classical arabinogalactan protein 7
- non-specific serine/threonine protein kinase
- Arabinogalactan protein 20
- Arabinogalactan protein 16
- Exosome complex exonuclease
Sequence:
MRGLFKSKPRTPADIVRQTRDLLLYADRSNSFPDLRESKREEKMVELSKSIRDLKLILYGNSEAEPVAEACAQLTQEFFKADTLRRLLTSLPNLNLEARKDATQVVANLQRQQVNSRLIAADYLESNIDLMDFLVDGFENTDMALHYGTMFRECIRHQIVAKYVLDSEHVKKFFYYIQLPNFDIAADAAATFKELLTRHKSTVAEFLIKNEDWFFADYNSKLLESTNYITRRQAIKLLGDILLDRSNSAVMTKYVSSMDNLRILMNLLRESSKTIQIEAFHVFKLFVANQNKPSDIANILVANRNKLLRLLADIKPDKEDERFDADKAQVVREIANLKLRELA
Protein: D-mannonate dehydratase (ManD) (EC 4.2.1.8) (G7TAD9)
Organism: Xanthomonas oryzae pv. oryzicola (strain BLS256)
Function: Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).
Interaction partners:
Sequence:
MSQPSDSTAPLQGSARDREIVEARVIVTCPGRNFVTLKIRTRSGITGVGDATLNGRELAVAAYLQEHLVPNLIGRDAGRIEDIWQFFYRGAYWRRGPVTMSAIAAVDVALWDILGKMAGMPLYQLLGGRSREGALVYGHANGRDIAETSDEVGRFREMGFIAIRAQCGVPGIKKTYGISVGGKPYEPAESELPTETVWSTPRYLGVVPRLFEQLRADHGDEIELLHDAHHRLTPIEAARLGRDLEPYRLFWLEDATPAENQRAFEIIRQHTVTPLAVGEVFNSIWDCKHLIEQQLIDYIRTTIVHAGGLTHVRRLADFAALHQVRTGFHGATDLSPVCMGAALHFDTWVPNFGIQEYMFHSDEANAVFPHDYQFRAGRLHCGETPGHGVDIDEALAARYPYTPKQLPILRLEDGTMGDW
Protein: Outer segment 5 (Q9VII8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}.
Interaction partners:
- Intraflagellar transport 52
- Intraflagellar transport protein 57 homolog
- No mechanoreceptor potential B, isoform D
- TRAF3-interacting protein 1
- Clusterin associated protein 1
- Intraflagellar transport 20
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 172 homolog
- Tetratricopeptide repeat protein 30 homolog
- Outer segment 6
Sequence:
MKLKTRICKKNSIRNSEKVEESSKSTTNCPLSCVDWSSNEEIYFVSDDHQIFKWSDVSRDSVEVAKLPDDFVPTDMHWLLLGGRSSGGGKGSDTLLICSNDGRFVILNKSARVERSISAHAAAISSGRWSPDGAGLLTAGEDGVIKIWSRSGMLRSTVVQNEESIRCARWAPNSNSIVFCQGGHISIKPLAANSKIIRWRAHDGLVLSLSWSTQSNIIASGGEDFRFKIWDAQGANLFTSAAEEYAITSVAFNPEKDYLLVGTFNLLKLCHSNGWSYNTARFSSPRVGSIFNLSWSADGTQATCGTSTGQLIVAYAIEQQLVSGNLKATSKSRKSITLKDIATGTQDILDFPQRVVSFGLGYGHLVVATTNQVHIYNEKYINTPIIIDGRNDTRVIEVGKKYFMILDALSIWVYTYTGRLHLNPRYPGSQAQIPLLTWRSLSLGLDVLAIRDNSDPTVLHLFDLIPGASRQYDPHSLRAKQQLVQIAACRAGSPEDQFVAFIDSNRELFVSESRNLNSERIDEIYKIGTQLTAIMWASETNILVGVHDSCYSIWYCPGEGASDPTIIALTTITLDTTEFGKHITIESFEESVLTFRSAGALLPVNVNMYCEILHRALLEGQWQQALKICRMGQHSSLWATLAAVATRKHQLQISEEAYSAALQIDKVSYLQHLKALTPSSAEQMAENSLMLGRMLEAETILLHGKKIEQAVGLALRMHNWRRALEISQKHKGEQPELVPRVLQERRKYLKALQREEWDPLYLPLVAKEEADNTSE
Protein: Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog) (Q08BY0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of 'Arg-118' of ndufs2 after it assembles into the complex I, stabilizing the early intermediate complex.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q7L592}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Peptide chain release factor 1-like, mitochondrial
- Arginine-hydroxylase NDUFAF5, mitochondrial
- Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- Electron transfer flavoprotein beta subunit lysine methyltransferase
- ATP synthase subunit gamma.
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH:ubiquinone oxidoreductase complex assembly factor 6.
- NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial
Sequence:
MRTLLRLKRLMPEVLWTKRSCSSSSINKSILKHLASKIIATGPISVAEYMREALTNPVLGYYVKNDMLGAGGDFITSPEISQIFGELLGVWCISEWMAAGKSSALQLVELGPGRGSLTSDILRVFSQLKGVLGETGISIHLVEVSPKLSQVQAECLTGNQTQTYDNNHTFYRSGTTCTGLPIYWYHSIEDVPRGFSIFLAHEFFDALPIHKFQRTENGWREVLVDIDPENPGKLRFVVSHRPTLASSTLIQKDESRRHVEVCAEAGVIVQKLASRIAEDGGAALIVDYGHDGTKTDTFRGFKGHQIHDVLEAPGLADLTADVDFSYLRKMAGDQVICLGPITQRSFLKNMGIDSRMQVLLSSNDPSIRAQLIHSYDMLINPEKMGERFQFFSVLNTARLAQREQMQKSTVMPVAGFTELEMQ
Protein: Calcitonin gene-related peptide 1 (CGRP1) (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I) (P06881)
Organism: Homo sapiens (Human)
Function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
Subcellular location: Secreted {ECO:0000269|PubMed:2408883}.
Interaction partners:
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA
Protein: Lysine-specific histone demethylase 1 homolog 1 (Lysine-specific histone demethylase 1C) (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Protein LSD1-LIKE 1) (AtLSD1) (Protein SWIRM-PAO 1) (AtSWP1) (Q8VXV7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin of the floral repressor FLOWERING LOCUS C (FLC) and the sporophytically silenced floral repressor FWA. Seems to act in partial redundancy with FLOWERING LOCUS D (FLD) to repress FLC expression. Required for cytosine methylation of FWA. Controls primary seed dormancy by regulating DOG1 and abscisic acid signaling-related genes. In association with OTU6/OTLD1, involved in transcriptional gene repression via histone deubiquitination and demethylation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:21690391}. Cytoplasm {ECO:0000269|PubMed:21690391}.
Interaction partners:
- Histone deacetylase 6
- OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 6
- Histone H3.3
- Histone H3-like 3
- Histone H3-like 5
- Histone H3-like 2
- Histone H3-like 4
- Histone H3-like 1
- Histone H3.1
- Histone H3-like centromeric protein CENH3
Sequence:
MSTETKETRPETKPEDLGTHTTVDVPGEEPLGELIADDVNEVVSDASATETDFSLSPSQSEQNIEEDGQNSLDDQSPLTELQPLPLPPPLPVEARISESLGEEESSDLVTEQQSQNPNAAEPGPRARKRRRRKRFFTEINANPAFSRNRRTSVGKEVDSEALIAMSVGFPVYSLTEEEIEANVVSIIGGKDQANYIVVRNHIIALWRSNVSNWLTRDHALESIRAEHKTLVDTAYNFLLEHGYINFGLAPVIKEAKLRSFDGVEPPNVVVVGAGLAGLVAARQLLSMGFRVLVLEGRDRPGGRVKTRKMKGGDGVEAMADVGGSVLTGINGNPLGVLARQLGLPLHKVRDICPLYLPNGELADASVDSKIEASFNKLLDRVCKLRQSMIEENKSVDVPLGEALETFRLVYGVAEDQQERMLLDWHLANLEYANATLLGNLSMAYWDQDDPYEMGGDHCFIPGGNEIFVHALAENLPIFYGSTVESIRYGSNGVLVYTGNKEFHCDMALCTVPLGVLKKGSIEFYPELPHKKKEAIQRLGFGLLNKVAMLFPCNFWGEEIDTFGRLTEDPSTRGEFFLFYSYSSVSGGPLLVALVAGDAAERFETLSPTDSVKRVLQILRGIYHPKGIVVPDPVQALCSRWGQDKFSYGSYSYVAVGSSGDDYDILAESVGDGRVFFAGEATNRQYPATMHGAFLSGMREAANILRVARRRASSSALNPNQICIDKEEEVDEEEDRCLDQLFETPDLTFGNFSVLFTPNSDEPESMSLLRVRIQMEKPESGLWLYGLVTRKQAIELGEMDGDELRNEYLREKLGLVPVERKSLSQEGESMISSLKAARLNRQIFD
Protein: FIST domain-containing protein (Q384U0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRRFYCIPWNCLVLSKPPLSRRLSSSTETPEAIRDAIAADERDQRRREEAVDGRSVVFACGSSADHRPRIAAAEAFDVAAAALSSTPNFCFMNVSMDYAGMIDAPEVVWYNLCKVNDVTPSTVRPQQLHMIGGATRLQRPGGGFVQVMLGCIPDLQSDTFTFDTIPEEDDLAEAHRPSPAICFALMDNKLTLQYERQLVAHLQVLSERLGGCPLTGGIYPAVQKSAGTTGDSGDETKEEKGSDNDLGDSLFFLNDRVYTGSAAGTVLRSEMVKAHNLSVVPSIAIRKVAVTSISSEVEGVFVVKTLEGRRATDVIHDVYCSPEMKGKPSRVFLGLQHNDFCIPVSFIGNPGTGELRFSAPKGISVAENGTVQLLVDDVELDSEVGAGALIGLHKRVAMTYATKDVNVAREARRNVVASSAAAFHYSHPGMNVLARPEVNITLGNSSVMYAPSLLQRCLGGYCSTTGVFCPGQVITLGNATGVFARSSSYTVLEGLK
Protein: Putative 12-oxophytodienoate reductase-like protein 2B (EC 1.3.1.-) (P0DI09)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative oxophytodienoate reductase that may be involved in the biosynthesis or metabolism of oxylipin signaling molecules.
Interaction partners:
Sequence:
METKQSIPLLMPYKMGPFNLSHRVVLAPLTRSRSYGNIPQPNAKLYYTQRTTPGGLLISESCVVSETSLGYPDLPGLWNRDQVEAWKPIVDAVHSKGGIFFCQIWHGGRVFHQDQPNGEAPVSSTDKPLMCKNMYGGQFKPPRRLRSDELPAIVNDFRIAARNAIEAGFDGVEVHGAHGYLIDQFLKDKVNDRSDQYGGSLENRCRFALEVIEAVVNEIGSDRVGIRLSPFADYMESGDSNPEALGLYLVQAMNKHGMESSTVTWLNLE