wanglab/gogpt-training-data huggingface dataset:
Protein: Pleckstrin homology domain containing, family A member 5 (A0A0N4SWF5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
GKAVNVSLADVRGGSHPNAGPLATEADRVIQRTNSMQQLEQWIKVQKGRGLEEEPRGVISYQTLPRNMPSHRAQILARCPEGYRTLPRNSKTRPESICSVTSSGHEKTGPGAEEKRRSMRDDTMWQLYEWQQRQFYHKQSTLPRHGCLSSPKAMVQVSDQTMHSIPTSPSHGSAAAYQGFSPQRTYRSEVTSPIQRGDVTIDRRHRPHHPKHVYVADRRSMPAGLTLQAVSPQSLQGRTLSQDECRGTLYKYRPEEAGIDAKLSRLCEQDKVVRALEEKLQQLHKEKYTLEQALLSASQEIEMNADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRDQMQGQLDRLGEVQSESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGSSETGLAGSKPFSSVKYKSEEEEVVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEDKKIHQVQGYPRNGSHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSETEAPVVKGSHFPVGVPLRTKSPTPESSTIASYVTLRKTKKMVELRTERPRSAVEQLCLAESARPRMTVEEQLERIRRHQQACLREKKKGLSVLGASDPSDVRDSPLRLTQTLRRDDNVKELDTVHRENDVKPDYETPAAQCAHLEDAEPQNADIGRKLKRSEMLYTPEPNGMASEEVTEKERQKEQVHADGSCSPQEETAMTEHQMEGPPEEAESLHEEEETLASCEPAPEIPRENQTTAALASVESSQS
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (Q8IPC5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
Interaction partners:
- GH01161p
- E3 ubiquitin-protein ligase lubel
- GH17761p
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-ribosomal protein eL40 fusion protein
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Polyubiquitin
- NF-kappa-B essential modulator
- RING-type E3 ubiquitin transferase
- RE66324p
Sequence:
MNSKSDYEAEKEKKLTITNRFGDSLENYELSNESEHKTHVYPKKIPNRKNGILKNTDANHSAVDNQHLEDVDLADILGTNWPKRAGPAAMILNNKSKTDPSNSVDLILKPASPILKIEPEEPLRFTIADYQPLIEIPGTELAIGSLVEVSNPGVCEDLYGVVRWIGIPPGPQKNVLVGIEVEDESNLKNVVASDGRHNGVRLFTCHDGRAIFVPANRCTADRRFADVDNSISANRVSSNHAKKFGVADCPAIYGSIPPLQIHNSDELASICGKFKGIQGHHNSCYLDATLFSMFTFTSVFDSILYRRPGPQDIRNYSEVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSGLTCEEKDPEEFLNSLLSQIMRVEPFLKLSSGQDSYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDCFGSLQAGSGLECTAFCPKCLKTFHSHIKRTNHVSKKIYSPKEFKIMAEHMVVPRLYMELFAVVCIETSHYVAFVKSGSGPDAPWCFFDSMADRKGEQNGYNIPEITCVPELTQWLSEEGARSINETSTNDKVLPEHAKRIFCDAYMCLYQSTDIMMYH
Protein: FAD/NAD(P)-binding domain-containing protein (Q2U4P3)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Interaction partners:
Sequence:
MMFTCNWTALLCALLSILSVCVADIPQTNYDVIIIGGGPSGLSAASALSRVLRKSVLFDSGEYRNNPTRHMHDVIGNDHVVPAEFRKTAREQISFYNMTTFIDQKVTKLEKTGDNAFQATVGDQQYTARKVILGSGVKDDLPDVPGLQEGFGKGIFWCPWCDGFEHRNQSMGVLGDISEAYGAVRELHPTLNKDIRIYANGTNTTEQIAILDKNHPNWRKVFQAYNVTVNNKPILNITRIQDGAVVNDPAIRLEFDKFQIYFADNSSEVRGAFITNYGTSQRSDLPAQLGVEMLGSKINTLRKGLQTSVPGVWGVGDANSDNSTNVPHGMSSGKSAAVYCHVELAQEELDRDAGLEKRETEFDAESFHETTERQMGSEIQDLYKRLSRR
Protein: Neuregulin 1 (A0A494C054)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MGKGRAGRVGTTALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLC
Protein: Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10) (Q80Y44)
Organism: Mus musculus (Mouse)
Function: Putative ATP-dependent RNA helicase.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q13206}. Nucleus {ECO:0000250|UniProtKB:Q13206}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q13206}.
Interaction partners:
- ESF1 homolog
- ATP-dependent RNA helicase DDX18
- Nucleolar MIF4G domain-containing protein 1
- Activator of basal transcription 1
- Ribosomal RNA processing protein 36 homolog
- Something about silencing protein 10
- Nucleolar protein 6
- Nucleolar protein 14
- U3 small nucleolar RNA-associated protein 18 homolog
- U3 small nucleolar RNA-associated protein 14 homolog A
Sequence:
MGKTVASLGQGTRPDPVRSFNRWKKKHSHRQHQKKERRKQLKKPEWQVEREGISRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETICFHATNLQMLVLDEADRILDMGFADTMNAIIENLPKKRQTLLFSATQTKSVKDLARLSLKDPEYVWVHEKAKYSTPATLEQNYIICELHQKISVLFSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGISILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEEQGMVQQLLQKKVPVKEIKINPEKLIDVQKKLESFLAQDQDLKERAQRCFVSYIRSVYLMKDKEVFNVSKLPITEYALSLGLAVAPRIRFLQKLEKQPSTELVKNPVTEAVPPRAPSLPNDEADESPAYVSEKMSVLHKSGERLEETEHRLASGDGDEEQDEETEDEETEDHLGKAREPHTESVVSIEEAQKVKEVSVQFLNRDDDDEDGPDADFLTVKRRDVFGLDLKENEALSKKEPSKSSVKKKLTKVAEAKKVMKRSFKVNKKITFTDEGELVQQWPQIQKCAIKDVEEEDDTGGINLDKAKERLQEEDKFDKEEYRKKIKAKHRERRLKEREARREANKRQAKARDEEEAFLDWSDEDDGGFDPSTLPDPDKHRSSEESESEDTNHKMSDTKKKQETRKRNNTEDDDVRPRSRHGKKAKWETVEPLDTGLSLAEDEELVLHLLKSQN
Protein: Myosin type-2 heavy chain 2 (Myosin type II heavy chain 2) (O14157)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Stabilizes the F-actin cables forming the F-actin ring that surrounds the nucleus during interphase. May work in conjunction with myo2.
Interaction partners:
- Myosin regulatory light chain 1
- Myosin regulatory light chain cdc4
- Actin
- Myosin type-2 heavy chain 1
- Tropomyosin
- Ras GTPase-activating-like protein rng2
- Cell division control protein 15
- Cell division control protein 12
- Alpha-actinin-like protein 1
- Ring assembly protein 3
Sequence:
MSYLSKNGSNDNNNIIKKLVDAEKHCNAVKDASFDERTWIWIPDSKESFVKAWIVEDLGEKYRVKLERDGSERIVDGFDAEKVNPPKFDMVDDMAALTCLNEPSVVNNLTQRYEKDLIYTYSGLFLVAVNPYCHLPIYGDDVVRKYQSKQFKETKPHIFGTADAAYRSLLERRINQSILVTGESGAGKTETTKKVIQYLTSVTDASTSDSQQLEKKILETNPVLEAFGNAQTVRNNNSSRFGKFIRIEFSNNGSIVGANLDWYLLEKSRVIHPSSNERNYHVFYQLLRGADGSLLESLFLDRYVDHYSYLKNGLKHINGVDDGKEFQKLCFGLRTLGFDNNEIHSLFLIIASILHIGNIEVASDRSGQARFPSLTQIDQLCHLLEIPVDGFVNAALHPKSKAGREWIVTARTREQVVHTLQSLAKGLYERNFAHLVKRLNQTMYYSQSEHDGFIGVLDIAGFEIFTFNSFEQLCINFTNEKLQQFFNHYMFVLEQEEYTQERIEWDFIDYGNDLQPTIDAIEKSEPIGIFSCLDEDCVMPMATDATFTEKLHLLFKGKSDIYRPKKFSSEGFVLKHYAGDVEYDTKDWLEKNKDPLNACLAALMFKSTNSHVSSLFDDYSSNASGRDNIEKKGIFRTVSQRHRRQLSSLMHQLEATQPHFVRCIIPNNLKQPHNLDKSLVLHQLRCNGVLEGIRIAQTGFPNKLFYTEFRARYGILSQSLKRGYVEAKKATITIINELKLPSTVYRLGETKVFFKASVLGSLEDRRNALLRVIFNSFSARIRGFLTRRRLYRFNHRQDAAILLQHNLRQLKLLKPHPWWNLFLHLKPLLGTTQTDEYLRRKDALINNLQNQLESTKEVANELTITKERVLQLTNDLQEEQALAHEKDILVERANSRVEVVHERLSSLENQVTIADEKYEFLYAEKQSIEEDLANKQTEISYLSDLSSTLEKKLSSIKKDEQTISSKYKELEKDYLNIMADYQHSSQHLSNLEKAINEKNLNIRELNEKLMRLDDELLLKQRSYDTKVQELREENASLKDQCRTYESQLASLVSKYSETESELNKKEAELVIFQKEITEYRDQLHKAFQNPEKTHNINDVKSGPLNSDENIYSTSSTTLSILKDVQELKSLHTKEANQLSERIKEISEMLEQSIATEEKLRRKNSELCDIIEALKYQIQDQETEIISLNADNLDLKDTNGVLEKNASDFIDFQGIKSRYEHKISDLLNQLQKERCKVGLLKQKTENRSVTQHTLDGNSPHPSFEEKHSGDPLKRIDGNNDDRKIDNKLLKTISKSLDALQLTVEEELSNLYSLSKDLSFTDISGHIPNSIRKLEKGLSTLSELKERLNASNSDRPSPDIFKDTQAIMNSRKLLSNPNSDAQSGLISSLQKKLYNPESNMEFTGLKPLSPSKISNLPSSQPGSPSKRSGKMEALIRNFDQNSSIPDPFIVNQRNSVLQTEFEKINLKLKEATKSGILDNKDLSKFSELIQSLLKENEELKNLTTSNLGSDDKMLDFAPLLEDVPNNTRNQIKGFVEKAISSKRAIAKLYSASEEKLFSTEKALREITKERDRLLHGLQGPSVPTSPLKAPTASQLIIPNFDGSITNYSGEEETEWLQEEVNIMKIKELTSTVNKYREQLAMVQSLNEHAESSLSKAERSKNYLTGRLQEVEELARGFQTTNADLQNELADAVVKQKEYEVLYVEKSNDYNTLLLQKEKLMKQIDEFHVIRVQDLEEREKKDQLLFQRYQKELNGFKVQLEEEREKNLRIRQDNRHMHAEIGDIRTKFDELVLEKTNLLKENSILQADLQSLSRVNNSSSTAQQNAQSQLLSLTAQLQEVREANQTLRKDQDTLLRENRNLERKLHEVSEQLNKKFDSSARPFDEIEMEKEVLTLKSNLAQKDDLLSSLVERIKQIEMFALKTQKDSNNHREENLQLHRQLGVLQKEKKDLELKLFDLDLKTYPISTSKDVRMLQKQISDLEASFAASDIERIKGIDECRNRDRTIRQLEAQISKFDDDKKRIQSSVSRLEERNAQLRNQLEDVQASETQWKFALRRTEHALQEERERVKSLETDFDKYRSLLEGQRVKRSESRLSMRSNRSPSVLR
Protein: Hexokinase-5 (EC 2.7.1.1) (Hexokinase I) (Q5W676)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Fructose and glucose phosphorylating enzyme. Functions as glucose sensor for plant growth and photosynthesis. Is essential for pollen development, germination, and tube growth. Its activity is necessary for the starch utilization pathway during pollen germination and tube growth, as well as for starch biosynthesis during pollen maturation.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- phosphoglucomutase
- phosphoglucomutase
- Os08g0545200 protein
- Probable glucosamine 6-phosphate N-acetyltransferase 2
- Os05g0164100 protein
- Phosphomannomutase
- mannose-6-phosphate isomerase
- Mannose-6-phosphate isomerase
- Xylose isomerase
- Os01g0952600 protein
Sequence:
MGKAAAVGTAVVVAAAVGVAVVLARRRRRRDLELVEGAAAERKRKVAAVIEDVEHALSTPTALLRGISDAMVTEMERGLRGDSHAMVKMLITYVDNLPTGNEQGLFYALDLGGTNFRVLRVQLGGKEKRVVQQQYEEVSIPPHLMVGTSMELFDFIASALSKFVDTEGDDFHLPEGRQRELGFTFSFPVSQTSISSGTLIKWTKGFSINDAVGEDVVSELGKAMERQGLDMKIAALVNDTVGTLAGGRYADNSVVAAIILGTGTNAAYVENANAIPKWTGLLPRSGNMVINTEWGSFKSDKLPLSEFDKAMDFESLNPGEQIYEKLISGMYLGEIVRRILLKLAHDAALFGDVVPSKLEQPFVLRTPDMSAMHHDSSHDLKTVGAKLKDIVGVPDTSLEVRYITSHICDIVAERAARLAAAGIYGVLKKLGRDKMPKDGSKMPRTVIALDGGLYEHYKKFSSCLESTLTDLLGDDVSSSVVTKLANDGSGIGAALLAASHSQYAEID
Protein: Lysine-specific demethylase 2A (EC 1.14.11.27) (F-box and leucine-rich repeat protein 11) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A) (P59997)
Organism: Mus musculus (Mouse)
Function: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis (By similarity). Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-BMAL1 heterodimer and RORA in a catalytically-independent manner (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9Y2K7}. Chromosome {ECO:0000269|PubMed:32584788}. Note=Punctate expression throughout the nucleoplasm and enriched in the perinucleolar region. Specifically nucleates at CpG islands where it's presence results in chromatin depleted in H3K36me2 (By similarity). {ECO:0000250|UniProtKB:Q9Y2K7}.
Interaction partners:
- S-phase kinase-associated protein 1
- Histone H3.2
- Histone H3.1
- Histone-lysine N-methyltransferase SETD2
- Lysine-specific demethylase 4A demethylase 4A) demethylase 4A)
- Ankyrin repeat and KH domain containing 1
- Lysine-specific demethylase 5A
- Lysine-specific demethylase 6A
- Lysine-specific demethylase 6B demethylase 6B)
- Lysine-specific demethylase 3A demethylase 3A)
Sequence:
MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQWPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLISVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDMELNELESGNGDEEGVDREARRMNNKRSVLTSPVANGVNLDYDGLGKACRSLPSLKKTLSGDSSSDSTRGSHNGQVWDPQCSPKKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSDKAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRPNPRVLMQHCPARNPQHGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRKELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS
Protein: Protein NODULATION SIGNALING PATHWAY 2 (LsNSP2) (Transcription initiator for nodulation) (Q2PEG7)
Organism: Lotus japonicus (Lotus corniculatus var. japonicus)
Function: Transcriptional regulator essential for Nod-factor-induced gene expression (Probable). Acts downstream of calcium spiking and a calcium/calmodulin-dependent protein kinase required for activation of early nodulation gene expression. Transcription factor involved in the induction of NIN and ENOD40 genes, which are required for rhizobial infection and early nodule development. Does not seem to contribute to the early steps of the arbuscular mycorrhizal fungus infection and colonization processes in roots. Transcription factor involved in the positive regulation of the beta-carotene isomerase D27, which participates in a pathway leading to biosynthesis of strigolactones in roots.
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:17244637, ECO:0000269|PubMed:24400899, ECO:0000269|PubMed:25560877}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q5NE24}. Note=Mainly localized to the nuclear envelope. Also found in the endoplasmic reticulum. Upon Nod-factor application, the nuclear envelope localization disappears and the protein accumulates in the nucleus. {ECO:0000250|UniProtKB:Q5NE24}.
Interaction partners:
Sequence:
MEMDIDCIHHLDFSGHSTLTNTPSSDNDNYGCSWNHWSPVVNWDAFTGNQDDFHHLIDSMIDDNNTGPAFSDHTASTTSEEEEEEEATTTTMTTTTTTTTTTPEAADDDFKGLRLVHLLMAGAEALTGANKNRELARVILVRLKELVSHTDGTNMERLAAYFTEALQGLLEGAGGAYNSSSKHHVIGGPHHEPQNDALAAFQLLQDMSPYVKFGHFTANQAIVEAVAHERRVHIVDYDIMEGVQWASLMQALASNPNGPHLRITALSRSGVGRRSMATVQETGRRLTAFATSLGQPFSFHHSRLESDETFRPAGLKLVRGEALVFNCMLNLPHLTYRSPNSVASFLTAAKALRPRLVTVVEEEVGSALGGFVERFMDSLHHFSAVFDSLEAGFPMQGRARALVERVFLGPRIVGSLARIYRTGGGGEERGSWREWLRAAGFSGVAVSSANHCQSNLLLGLFNDGYRVEELGSNKLVLHWKTRRLLSASLWTCSSESDCA
Protein: Uncharacterized nucleolar protein C2C4.08 (O14041)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized protein C25H2.10c
- Probable transcriptional repressor C1348.12
- UPF0612 protein C337.02c
- Uncharacterized mitochondrial carrier C12B10.09
- Uncharacterized transcriptional regulatory protein C11D3.11c
- Putative alpha-ketoglutarate-dependent sulfonate dioxygenase
- Uncharacterized RNA-binding protein C57A7.13
- Clustered mitochondria protein homolog
- Probable glutathione-independent glyoxalase hsp3104
- Probable oligoribonuclease
Sequence:
MNRLQAKKAVNVSRHEQKRIRYKLTPEEVKAERKERKRRAAIQRAEKKLIRAKGEALVAFQAVSNPSCNFLVIDFEAYEFNQKIITEAGITMRINGEWDYHHYRIKNFLHLRNGRFVPDEADNFQFGDSKIVTKIAFISILKKILKTPNLHLVGHGVENEIKYANVLGIPIPKDVTVLDTQNVFSFFQSLFLKEISNSNNISLAKMLTHLNIRAFCLHNAGNDARYTSEALREMTNKFTLSNF
Protein: Ras-interacting protein 1 (J9PJE8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MEESGSPRFRKLHFPVGLWINSPRKHFAKLGARWPSAASVKSTTSSDAASLHEAPSSVPSSLSHSTPSLAPPSPSPSPAFLRPRPANQQSRAKRLSHLFLRGRSNSDRDRAIGEREREIWAHSATPSSHHYLPPASSNAPGLVKIYGDALSSGANYRSLLANMHSTARQLIQQVITRYTERERENESEDTALQKYFPEDFLLCDVIGKPIHQADGAVKWQTECRRGVASWECPLQLVDMWRPKDGFERRFEIQRLDEYEREEKEKEKERERDGESYQGVRWRRSRMSSGGGAEEERGHRGRNSELRRSISDMNLSLRRRQGNTGNDPRRSGCAQNNGQDRKNIVSMIATEGGEVSGSRGGVSESDRRTRVAEEDKDTCDLEVMSQSLILPPTDRPYFLLLQGYDQSKDFVLYIMAGHTHVFGRKPTFREREMDREREKKGKRPLKVDTYLSAPDLLARHLLIRRDTAVPEQPHGQALARPFRGGQATLNGAPLYREAVLKPGDLLGLGSHFLFLYRDPRVTPVPPLALPPPWQGDMPTSFGPGGMTDRQEMLRLYLGSTESLLRYQAKHADALLQEIILKNTSPDSGGGALAPAYLLSLMIDYASKHLDPELTPQLLLKAANQIKGIVWDKIKEFGDKHPTQNSADAEVDLPPPSAQKLSSDLRPLMFWMSNATELLNFFQVKVEALEKEWEFEAPGDPVLSADMDTCSEALAQLDDVIMHTFQQCVYHLTKTLYSLLPALLDTNPFSSEERKKAKAGVKDKTGSGGEGDEEEDGSALPPTVAGLVEVYRCSLQLSREACLSPPLTSQTFGYLFFFTNTSLLNTLLERDNLFSWSRAVQIRTNLDLVLDWLQGAGLGDIASEFLKKLSVTVNFLCIPKTRLIQSSWSSLQEEHPLLSPSQLHHLLTHYKLGPTRAPPSSWAPPLGTELGGDIFESFLDHPPLILPNETPRLDLTQPIPSPELQKEVTRLRTFLWGLDQDELPANQRTRL
Protein: Hemin receptor (Q56989)
Organism: Yersinia pestis
Function: This protein is involved in the initial step of iron uptake by binding hemin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment.
Subcellular location: Cell outer membrane {ECO:0000255|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU01360}.
Interaction partners:
- Hemin transport protein HmuS
- Hemin-binding periplasmic protein HmuT
- TonB protein
- Hemin import ATP-binding protein HmuV
- Hemin transport system permease protein HmuU
- Putative membrane protein
- Putative mucin/carbohydrate-binding domain-containing protein
- Enhancing factor
- Similar to Bacteriophage HK97 tail fiber Stf TR:Q9MCR6
- Irp1 protein
Sequence:
MLRSTSDRFRWSSLSLAIACTLPLATQAADTTTTQTSSKKHSTDTMVVTATGNERSSFEAPMMVTVIEGNAPTSQTAATAADMLRQVPGLTVTGSGRTNGQDVVMRGYGKQGVLTLVDGVRQGTDTGHLNSTFLDPALVKRIEIVRGPAALLYGSGALGGVIAYETVDAADMLQPGQNSGYRVYSSAATGDHSFGLGASAFGRTDDLDGILSFGTRDIGNIRQSNGFNAPNDETISNVLAKGTWQIDSIQSLSANLRYYNNSAIEPKNPQTSAPSSTNVMTNRSTIQRDAQLRYNIKPLDQEWLNATAQVYYSEVEINARPQGSAEEGREQTTEGVKLENRTRLFIESPASHLLTYGTETYKQEQTPGGATESFPQAKIRFSSGWLQDEITLRDLPVSILAGTRYDNYSGSSDGYADVDADKWSSRGAISITPTDWLMLFGSYAQAFRAPTMGEMYNDSKHFAIPIRPGLTLTNYWVPNPNLKPETNETQEYGFGLRFSDLLMAEDDLQFKVSYFDTKAKDYISTRVDMQAMTTTSVNIDQAKIWGWDASMSYKTALFNWDLAYNRTRGKNQNTDEWLDTINPDTVTSIVDVPVANSGFSVGWIGTFANRSSRVSSSTPQAGYGVNDFYVSYKGQEAFKGMTTTMLLGNVFEKEYYTPQGIPQDGRNVKFFVSYQW
Protein: Catalase (EC 1.11.1.6) (A0A384P5Q0)
Organism: Homo sapiens (Human)
Subcellular location: Peroxisome matrix {ECO:0000256|ARBA:ARBA00004253}.
Interaction partners:
Sequence:
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
Protein: Zona pellucida sperm-binding protein 1 (Zona pellucida glycoprotein 1) (Zp-1) [Cleaved into: Processed zona pellucida sperm-binding protein 1] (P60852)
Organism: Homo sapiens (Human)
Function: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.
Subcellular location: [Processed zona pellucida sperm-binding protein 1]: Zona pellucida {ECO:0000269|PubMed:29895852}.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P48829}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Zona pellucida sperm-binding protein 3
- Zona pellucida sperm-binding protein 2
- Zona pellucida sperm-binding protein 4
- Oviduct-specific glycoprotein
- Growth/differentiation factor 9
- Factor in the germline alpha
Sequence:
MAGGSATTWGYPVALLLLVATLGLGRWLQPDPGLPGLRHSYDCGIKGMQLLVFPRPGQTLRFKVVDEFGNRFDVNNCSICYHWVTSRPQEPAVFSADYRGCHVLEKDGRFHLRVFMEAVLPNGRVDVAQDATLICPKPDPSRTLDSQLAPPAMFSVSTPQTLSFLPTSGHTSQGSGHAFPSPLDPGHSSVHPTPALPSPGPGPTLATLAQPHWGTLEHWDVNKRDYIGTHLSQEQCQVASGHLPCIVRRTSKEACQQAGCCYDNTREVPCYYGNTATVQCFRDGYFVLVVSQEMALTHRITLANIHLAYAPTSCSPTQHTEAFVVFYFPLTHCGTTMQVAGDQLIYENWLVSGIHIQKGPQGSITRDSTFQLHVRCVFNASDFLPIQASIFPPPSPAPMTQPGPLRLELRIAKDETFSSYYGEDDYPIVRLLREPVHVEVRLLQRTDPNLVLLLHQCWGAPSANPFQQPQWPILSDGCPFKGDSYRTQMVALDGATPFQSHYQRFTVATFALLDSGSQRALRGLVYLFCSTSACHTSGLETCSTACSTGTTRQRRSSGHRNDTARPQDIVSSPGPVGFEDSYGQEPTLGPTDSNGNSSLRPLLWAVLLLPAVALVLGFGVFVGLSQTWAQKLWESNRQ
Protein: Protein RAFTIN 1A (TaRAFTIN1a) (BURP domain-containing protein 1A) (Q70KG5)
Organism: Triticum aestivum (Wheat)
Function: Required for pollen development. Probably synthesized in the tapetum, packaged in Ubisch bodies and transported at appropriate stages to the micropsores.
Interaction partners:
- RING-type E3 ubiquitin transferase
- RING-type E3 ubiquitin transferase
- RING-type E3 ubiquitin transferase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
Sequence:
MARFLVALLATTLVAVQAGGQLGHAAPATAEVFWRAVLPHSPLPDAVLRLLKQPAAGVELLTEATSFVRDAEDRPPFDYRDYSRSPPDDEPSKSTGAASGARDFDYDDYSGGDKLRGAASGARDFDYDDYSGADKLRGATDEYKAPSSSLAGNGASMARGGKAETTTVFFHEEAVRVGKRLPFRFPPATPAALGFLPRQVADSVPFTTAALPGVLATFGVASDSATVASMEATLRACESPTIAGESKFCATSLEALVERAMEVLGTRDIRPVTSTLPRAGAPLQTYTVRSVRPVEGGPVFVACHDEAYPYTVYRCHTTGPSRAYMVDMEGARGGDAVTIATVCHTDTSLWNPEHVSFKLLGTKPGGTPVCHLMPYGHIIWAKNVNRSPA
Protein: Type-1 angiotensin II receptor B (Angiotensin 2 receptor, type 1-B) (Angiotensin II receptor, type 1-B) (Angiotensin type 1 receptor) (AT1 receptor 1) (XAT-1) (P35373)
Organism: Xenopus laevis (African clawed frog)
Function: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P30556}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P30556}.
Interaction partners:
Sequence:
MLSNISAGENSEVEKIVVKCSKSGMHNYIFITIPIIYSTIFVVGVFGNSLVVIVIYSYMKMKTMASVFLMNLALSDLCFVITLPLWAVYTAMHYHWPFGDLLCKIASTAITLNLYTTVFLLTCLSIDRYSAIVHPMKSRIRRTVMVARLTCVGIWLVAFLASLPSVIYRQIFIFPDTNQTVCALVYHSGHIYFMVGMSLVKNIVGFFIPFVIILTSYTLIGKTLKEVYRAQRARNDDIFKMIVAVVLLFFFCWIPHQVFTFLDVLIQMDVIQNCKMYDIVDTGMPITICIAYFNSCLNPFLYGFFGKKFRKHFLQLIKYIPPKMRTHASVNTKSSTVSQRLSDTKCASNKIALWIFDIEEHCK
Protein: A disintegrin and metalloproteinase with thrombospondin motifs 18 isoform X1 (ADAM metallopeptidase with thrombospondin type 1 motif, 18) (E7FEJ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- Coiled-coil domain-containing 51
Sequence:
MHTNMDCLFLLLWSLQVPLVTCTSFRSLASVSFGNFLKAVQFCCLHSVASVSFTGDTGGLYQDYDFATPVEVDSYGGYISHDVSRHGRSRRSLSEAGSLVHYHVSAFGKELHLDLQPSHVLAEGFTVQTLGAEGINTATLDPSIHNCFYQGSIRNHSDSSVALSTCTGLSGLIRYSSEELFITPLPQHLALQHNYSAPSGHHPHVIYKRSAERRVHADKTDRTSRFKSSNPYEDHHHHHHHHRHHDYQHGKLQRQHFCGRRKQYTPKPPTEDHFVMPDEFEQQIRVKRSEITSSKEGGLNVETLVVADRKMLEKHGRDNVTTYVLTVMNMVSSLFKDGTIGNDINIVVVSLLLLEKDPLGLSINHHADQSLNSFCQWQSGLVGKNGKRHDHAILLTGLDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHDGEGNPCRKTEGNIMSPTLAGNNGVFSWSACSRQYLNRFLGTAQASCLVDEPKQIGQYKYPEQLPGQLYDADIQCKWQFGSKAKLCGLDFVKDICKSLWCHRTGHRCETKFMPAAEGTICGADMWCRKGQCVKFGDHGPKAVHGQWSGWSEWSDCSRTCGGGVMYRERSCNSPSPQHNGKFCQGPGRLHQLCNTKPCQPDGVDFRAQQCAEYNSKPFRGWYYKWKPYTKVEEEDICKLYCIAEDFDFFFAMSSKVKDGTSCSDYKGGVCIDGICEPVGCDQVLGSKAALDACGVCKGDNSTCKFYSGQYTLQHRANEYYPVVMVPAGARSIQVQEMEISNSYLAVRSLKRGTYYLTADWTVDWPGRFQFAGTTFNYQRSFNRPETLFATGPTNETLLFEILLQGKNPGITWEYTLPHPEKKHNYTWSVVRSDCSAPCAGGRVSTKAICLQDQQTQVNSSLCNPQTRPVVGSHLCNTQPCPAYWTTGKWGVCSRTCGGGQQTRNIRCLRKVTYQREEVAAQSLCPVMAPAQLQPCNTQSCPPEWSTSSWTQCSKTCGRGLKKRSVFCRSTDPGARAVVVPDSMCKLHLKPKAQESCVLSRCPKNERLQWITSAWGECSASCGAGVRRRELHCGEKDSQGGYTEFPARRCRNLQKPEADLEQSCNNGPCPEPLAPQLLQPGGPSVTLGWYSSPWLQCTVSCGGGVQTRSVQCLRQGRPSVGCFPHQRPISSRACNTHFCPAPIPVPVPPPSPTLKEDQPCIDFFSWCHLVPQHGVCNHKFYGQQCCKSCSAKRQ