wanglab/gogpt-training-data huggingface dataset:
Protein: 21.9 kDa heat shock protein (OsHsp21.9) (Q53M11)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Endoplasmic reticulum {ECO:0000305}.
Interaction partners:
Sequence:
MAAVAEREVLGMVAAVAAMVVMMAPPAAALVPYGYGYMLDDPFRVLEQSPLRPAGGVAAAAAAGEPAAVALARCDWKETPEAHVVTVDVPGVRRGDVRVEVDEASRVLRVSGERRRAGAAEEEEGERDGVRWHRAERAAGRFWRRFRMPPGADVGRVAARLDDGVLTVTVPKVPGHRGREPRVVAIDGAGAGDMEAEVVKASKAEM
Protein: Protein kinase C (EC 2.7.11.13) (B8A467)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Muscle RAS oncogene homolog
- small monomeric GTPase
- Ras-related protein M-Ras
- RAS-related
- GTPase NRas
- small monomeric GTPase
- HRas proto-oncogene, GTPase a.
- RAS-related 2
- Protein kinase C
- Ezrin
Sequence:
MVVFNGLLKIKICEALDLKPTAWSLRHAVGPKTQTFLLDTYIALNVDDFRVGQTSTKQKTNSPAWHDELVTEVHDGRKIELSVFHDAPIGYDDFVANCTIQFEELLHNGSKHFEDWIDLEPEGKVFVIIDLSGSSSEAGGCENEERVFRERMRPRKRQGAVRRRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVLGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQEDTAEEVGSQRFSVNMPHKFRIHNYKVLTFCDHCGSLLWGLLRQGLQCKVCKMNVHKRCEINVAPNCGVDARGIAKVLSDLGVTPDKLSGSVQRRKKISQGPDPHPLPISPLLEEDRCKSAPTSPCDQDIKDLENIRKALSFDHRSEEMKQASEGVSEETGEARENGEVKTVQAKRMMLEDFSFIKVLGKGSFGKVMLAELRGTDEVFAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEARSRFYAAEVTSALMFLHHNGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILDGITTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKSPSKRLGCVVSQGLEDAIKVHPFFKDIDWVLLEQRKVKPPFKPRIKTKRDVNNFDQDFTREEPVLTPVEDAIIKQINQEEFKGFSYFGEETLS
Protein: Histone promoter control protein 2 (Q01448)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the HIR complex, which functions as a histone chaperone that cooperates with ASF1 to promote replication-independent chromatin assembly. The HIR complex is also required for the periodic repression of three of the four histone gene loci during cell cycle as well as for autogenous regulation of the HTA1-HTB1 locus by H2A and H2B. DNA-binding by the HIR complex may repress transcription by inhibiting nucleosome remodeling by the SWI/SNF complex. The HIR complex may also be required for transcriptional silencing of centromeric, telomeric and mating-type loci in the absence of CAF-1.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Chromosome {ECO:0000269|PubMed:19683497}. Note=Localizes to the promoter region of histones HTA1-HTB1. {ECO:0000269|PubMed:19683497}.
Interaction partners:
- Protein HIR2
- Histone transcription regulator 3
- Protein HIR1
- Histone chaperone ASF1
- Histone chaperone RTT106
- Protein SPT10
- Chromatin assembly factor 1 subunit A
Sequence:
MDQKAIVLDNSKSGSKQTKSSGKMQTQTDTNAEVLNTDNSIKKETGSDSEDLFNKFSNKKTNRKIPNIAEELAKNRNYVKGASPSPIIISGSSSTSPSGPSSSSTNPMGIPTNRFNKNTVELYQHSPSPVMTTNKTDTEEKRQNNRNMDNKNTPERGSSSFAAKQLKISSLLTISSNEDSKTLHINDTNGNKNSNAASNNIPSAYAELHTEGNSIESLIKPPSSPRNKSLTPKVILPTQNMDGTIAKDPHLGDNTPGILIAKTSSPVNLDVESTAQSLGKFNKSTNSLKAALTKAPAEKVSLKRSISSVTNSDSNISSSKKPTSEKAKKSSSASAILPKPTTTKTSKKAASNSSDSTRKKNASNKTTSAIKKESNAGSKLNTVKKENSSLSSIKATEKEKDKGGNSTEAKNSTSNVRKEPTAKSPKRLVAAPTVSPPKILQTAETKAKEPSILIDVPLYQADTNDYLDENGQVIFNLSTLIKEKYHPKSKELAQLKDSKRNLLMQLSDHSNGSLEKEKDEEGDVIELDDDEDMEEDEGEIDTETNTVTTTISPKKKSHPMKGKNLIGKYDVEDPFIDDSELLWEEQRAATKDGFFVYFGPLIEKGHYASLERANGTMKRGGVKNK
Protein: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16) (P62139)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Regulates NEK2 function in terms of kinase activity and centrosome number and splitting, both in the presence and absence of radiation-induced DNA damage. Regulator of neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E (By similarity). Dephosphorylates CENPA (By similarity). Dephosphorylates the 'Ser-139' residue of ATG16L1 causing dissociation of ATG12-ATG5-ATG16L1 complex, thereby inhibiting autophagy (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62136}. Nucleus {ECO:0000250|UniProtKB:P62136}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:P62136}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62136}. Note=Primarily nuclear and largely excluded from the nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. NOM1 plays a role in targeting this protein to the nucleolus. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles. {ECO:0000250|UniProtKB:P62136}.
Interaction partners:
- Retinoblastoma-associated protein
- Protein phosphatase 1 regulatory subunit 3A
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- WD repeat-containing protein 82
- Protein phosphatase 1 regulatory subunit
- Protein phosphatase 1 regulatory subunit 3C
- Protein phosphatase 1 regulatory subunit 3E
- Leucine-rich repeat protein SHOC-2
- Protein phosphatase 1 regulatory subunit 1B
- Intersectin 2
Sequence:
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
Protein: Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) (Q9DA19)
Organism: Mus musculus (Mouse)
Function: Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription (By similarity). May modulate splice site selection during alternative splicing of pre-mRNAs.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:15652350}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Colocalizes with NEK6 in the centrosome. {ECO:0000250}.
Interaction partners:
- Recombining binding protein suppressor of hairless
- Recombining binding protein suppressor of hairless-like protein
- Histone deacetylase complex subunit SAP30
- Nuclear receptor corepressor 2
- SNW domain-containing protein 1
- Histone deacetylase 1
- Histone deacetylase 2
- Histone deacetylase complex subunit SAP30L
- Paired amphipathic helix protein Sin3a
- Pre-mRNA-splicing factor CWC25 homolog
Sequence:
MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGVKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQDYVASDCEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKKSDKKKKKLQKSKNKHKKRKNKSPSSSSSSSSSSSSSSSSSSSSSSSSETSDSSSESDNKEKKREKEKRKKKKKTKCSESKSSDCKEDKPKNMLYEELSSSHSDRGKAQEKLRFPKQESSGENSMWVHSASDRTSRSHRHSPEKKGSDRNRGIRSRSRSRAESSRRSRSRSPYRQKHREVRSRPHRSPSEEQKGRKGTRSHGEGDHRREHVR
Protein: Probable trafficking protein particle complex subunit 2 (TRAPP subunit 20 ortholog) (Q9VUZ1)
Organism: Drosophila melanogaster (Fruit fly)
Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi. Involved in dsRNA uptake.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P0DI81}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P0DI81}. Golgi apparatus {ECO:0000250|UniProtKB:P0DI81}.
Interaction partners:
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit 6B
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit 2-like protein
- FI18195p1
- Protein brunelleschi
- Trafficking protein particle complex subunit 11
- Trafficking protein particle complex subunit 10
Sequence:
MSTYYFVIVGQNDNPIYEKEFSTVNKELRKEDHRHLTQFIAHAALDLVDEHKWKTANMQLKSIDRFNQWFVSAFITASQIRFIIVHDNKNDEGIKNFFNEMYDTYIKNSMNAFYRINTPIKSPMFEKKSEIFGRKYLLS
Protein: Expressed protein (Transmembrane protein) (Q45GJ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEVPKGFFEKLWSFVSFLPYFFLLLLLGVTKALIIGPISSAIILVGNSCVIIGLWPAHFIWTYYCLARTKRIGLVLKTLALVLFPLPLLLWPVAGIVGSLFGGIAYGFFTPLMATFEAVGESVTSKCYHCFVDGSFSTIKGSCTVVTDFTDFCFHSYFSYMDELREMVSADVEPLEIKLSRLPSCLLASLIGVMVDVLLITAVAVYKSPYMLLKGWKRLLEDLVGREGPFLESVCVPFAGLAILLWPLAVAGAVIASVLSSFFLGLYSGVIVHQEDSFRMGLNYIIAAVSLFDEYVNDLLYLREGTSLPRPCYRTKTETVHGKRILGESKNVDLKSKRSSSLGSKLVSEQSRTLKKAITLYKPVQVWEWLFKSCEVNGRILLRDGLIDVKDVEECLVKGNSKKLYIKLPAWTVLQCLLASAKSNSSGLVITDGVELTELNSPRDKVFVWLVGPLLIMKEQIKNLKLTEDEEFCLRKLVMVCKNERTEDWDNTGFPSSDTVRKAQLQAIIRRLQGMVASMSRIPTFRRRFMNLVKVLYIEALEMGASGNRAGGILKPNSDQTGNLDRTETPDMDVV
Protein: Uncharacterized protein (Q586E3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
Sequence:
MSTVKAAAAAPTGSILQCRSSAPKSKMGENEEKRGGASEGTTHTQNLVTVDTAQTSQPSATRPPAPTSGLGQVIPISPPNGQLGSRNTVPPQRQGLFQGQGVMGNMQEPAAGGGAYWGTMGGYTYGVAPTGSASNAFYPSARNGGCVFPPLQGRMAGYPPAVPPPPSLFQGQFPSGGRGIVATGCGARSVCGYALDGFARGGRVRQHTTGTSAHEGAVCESVHGPALGDVSNPLPYSVYGEGHAFPSLPGRLAGHLPQRRNSFQQQGSFHSQRELGDLHASAAGESIYGGCGYALSFRCFVPGTSDTGVCGSAVHDSSYGNRNGISQMGSIYGNGVGRVPSPLRTSLCPVIATIKDHVPLQRSGLRGGNVVAVGAAKCGGEGRSADELKPVLASPGRSLASQSECSPAGDDSSAQTLVLENYNIHSLVILDKDEGPSDKVVVTVKDPRTVVFRRSDGGEEEHVNDECLERSEASAYVNSVLLNDLRLNWIAGRTSALLVGAGRNCGDTSVTFAGDFLQRCLESVEGAKEKCKYFDVTITLGMMESSDRILDLLDTEKKGYERVQLASNPVYGPCLLGMKTKKATSSKECMEVFNSAMQLVDNPKHLIVGFFVLKQLKKTANGGDVYLSSLCIGLAKEEVSRFAALKEKDTSEPHRLFRYAIGGGSVTVSTLILSQCDTGASDSLDVERRMREVKNTPPRIGSVLRCVESAKKEINRQQEKMKDMDSTGKEPTARLVSRMESIVRDAEEMLANPITTAPKGYLIV
Protein: Small ribosomal subunit protein uS4c (30S ribosomal protein S4, chloroplastic) (P0C488)
Organism: Oryza sativa subsp. japonica (Rice)
Function: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- 40S ribosomal protein S29, putative, expressed
- Small ribosomal subunit protein eS19
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS9
- Os10g0411700 protein
- Small ribosomal subunit protein uS2c
- 40S ribosomal protein S30
- Small ribosomal subunit protein uS5c
- Small ribosomal subunit protein uS8c
- Small ribosomal subunit protein uS19
Sequence:
MSRYRGPRFKKIRRLGALPGLTRKTPKSGSNLKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKSSTGQVLLQLLEMRLDNILFRLGMASTIPEARQLVNHRHILVNGRIVDIPSFRCKPRDIITTKDNQRSKRLVQNSIASSDPGKLPKHLTIDTLQYKGLVKKILDRKWVGLKINELLVVEYYSRQT
Protein: mRNA 3'-end-processing protein RNA14 (P25298)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex.
Subcellular location: Nucleus. Cytoplasm. Note=Nucleus and/or cytoplasm.
Interaction partners:
- Protein PCF11
- Pre-mRNA polyadenylation factor FIP1
- mRNA 3'-end-processing protein RNA15
- Protein CFT1
- RNA end formation protein 2
- mRNA 3'-end-processing protein YTH1
- mRNA cleavage and polyadenylation factor CLP1
- Pre-tRNA-processing protein PTA1
- Poly
- Endoribonuclease YSH1
Sequence:
MSSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQCLSGKLENNDLSLWSTYLDYIRRKNNLITGGQEARAVIVKAFQLVMQKCAIFEPKSSSFWNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLRTANKKNIPQPGTSDSNIQQLQIWLNWIKWERENKLMLSEDMLSQRISYVYKQGIQYMIFSAEMWYDYSMYISENSDRQNILYTALLANPDSPSLTFKLSECYELDNDSESVSNCFDKCTQTLLSQYKKIASDVNSGEDNNTEYEQELLYKQREKLTFVFCVYMNTMKRISGLSAARTVFGKCRKLKRILTHDVYVENAYLEFQNQNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEKVQDLTQLKEIYKKMISYESKFGNLNNVYSLEKRFFERFPQENLIEVFTSRYQIQNSNLIKKLELTYMYNEEEDSYFSSGNGDGHHGSYNMSSSDRKRLMEETGNNGNFSNKKFKRDSELPTEVLDLLSVIPKRQYFNTNLLDAQKLVNFLNDQVEIPTVESTKSG
Protein: Probable oxidoreductase AIM17 (EC 1.14.11.-) (Altered inheritance of mitochondria protein 17, mitochondrial) (Found in mitochondrial proteome protein 12) (P23180)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:20150421}.
Interaction partners:
- Glyoxylate reductase 1
- Protein adenylyltransferase SelO, mitochondrial
Sequence:
MLRSNLCRGSRILARLTTTPRTYTSAATAAAANRGHIIKTYFNRDSTTITFSMEESSKPVSVCFNNVFLRDASHSAKLVTTGELYHNEKLTAPQDIQISEDGKSLVVKWKDGGHHQFPLQFFIDYKGSSFVSPATRKQESRYRPQLWNKRILKDNVKDLLSVSYNEFIDPKDDSKLFQTLVNLQKFGIAFISGTPSSSSEGLTIQKICERIGPIRSTVHGEGTFDVNASQATSVNAHYANKDLPLHTDLPFLENVPGFQILQSLPATEGEDPNTRPMNYFVDAFYATRNVRESDFEAYEALQIVPVNYIYENGDKRYYQSKPLIEHHDINEDNTLLGNYEALIKCINYSPPYQAPFTFGIYDKPSDLNNNLDLNLITTPAKLTERFLFKSFIRGLNLFESHINDFNNQFRLQLPENCCVIFNNRRILHANSLTSSNQQWLKGCYFDSDTFKSKLKFLEEKFPHDK
Protein: von Willebrand factor A domain-containing protein 8 (Q8CC88)
Organism: Mus musculus (Mouse)
Function: Exhibits ATPase activity in vitro.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:28414126}.
Interaction partners:
Sequence:
MQSRLLLLGAPGGLGDVASRRVRLLLRQVLRGRPGGDQQRLEVRLLHSGATDSGETVSIGDVSYKLKTPKNPELVPQNYISDSPAQSIVQHLRWLMQKDLLGQDVFLIGPPGPLRRSVAMQYLELTKREVEYIALSRDTTETDLKQRREIRAGTAFYIDQCAVRAATEGRTLVLEGLEKAERNVLPVLNNLLENREMQLEDGRFLMSAERYDKLLQDHTKEELDAWKIVRVSENFRVIALGLPVPRYSGNPLDPPLRSRFQARDIYFLPFQDQLKLLYSVGANVSAEKISQLLSFATTLCSQESSTLGLPDFPLDSLPEAVQILDSFPMMSIEHALQWVYPYTLLLGHEGKMAVEGVLKRFELQGSGHSLLPKEIVRVERMTDSHGSYAHVTIRVAGKEVTIKVPAGTRAVNQPCAPDHFIQTVSHKQLLAEMVQSHMVKDICLIGGKGCGKTVIAKNFAALLGYSIEPIMLYQDMTARDLLQQRYTLPNGDTAWRSSPLVSAAREGKLVLLDGIHRVNAGTLAVLQRLIHDRELSLYDGSRLLREDRYLSLKEKLQLTDEQLQNRSIFPIHPSFRIIALAEPPIVGSTTQQWLGPEFLTMFFFHHMKPLVKSEEIQVIKETVPNVPQEALEKLLSVTHKLRETQDPTAQSLAASLSTRQLLRISRRLSKYPSENLHDAITKACLSRFLPSLAQSALEKNLADAAIETNTEDSLEPELENYKCEVVAGSLKIGAVSVPVHNAHEKMKVPDVLFYDNVQHMVVMEDMLKDFVLGEHLLLVGNQGVGKNKIVDRFLHLLNRPREYIQLHRDTTVQSLTLQPTVKGGLIVYEDSPLVKAVKLGHILVVDEADKAPTNVTCILKTLVENGEMILADGRRIVADAANVDGRENLVAIHPDFRMLALANRPGFPFLGNDFFGTLGDIFSCHAIDNPKPHSELSMLKQYGPDVPEPVLQKLVAAFGELRNLADQGIINYPYSTREVVNIVKHLQKFPTEGLSSVVRNVFDFDSYNNDMREILMNTLHKYGIPIGAKPTNVQLAKEFPLPEKTFMGYWIVGQTGNGMQKVLCPAETNHVDIKGPVLVNMEKYPIEKHEARFLSFTEECTSWKFPLDEVNLICDIAVSHENGEQTLYVAACNPVSLYFMNMTGKNGFFVDFFDIFPRMASGSWRPFVTVAPLGSPLRGQVVLHEEQSNAVLLLDTTGSAIRRLVLPTEEFTSKKSSWWSKEEGETYRMCKEFSHKNWVVFYKQTGNSLTVLDVLEGLAHTISLPINLRTVFLVAEDKWLLVENETNQKYLLTKPAHIGSEDTGACQLYMLKEELPSTGFGVTQETEFCIPDKVSSDQLSSENLTSAVGQKIASPNRILSDENSHATIVVGFPDLMSPSEVYSWKRSSSLRQPSVTSMTMYTGKRTNATPRHNNCVTLTHTNQVVRILPPGEVPLKDLYPKDVTPPQTAGYIEVTDLQAKKLRYIPVPSAESLSPYTAWISAISDTDALLAEWDKSSVVTVDMGGRVRLWETGLERLQQSLMEWRNMIGQDSDKHVQITIERDSNEDVSDPKHGKEDPDNMPHVGGNTWAGGTGGRDTAGLGGKGGPYRLDAGHPVYQVSEVEKDAVPEDVKRAAREMAQKAFQQRLKEIQMSEYDAATYERFSSAVQRQVHALRIILDNLQAKGKERQWLRHQATGELDDAKIIDGLAGEKSIYKRRGDLEPQLGSPQQKPKRLRLVVDVSGSMYRFNGVDRRLERSMEAVCMVMEAFENYEEKFKYDIAGHSGDGYNIKLVPVNQIPKNNKQRLEILKTMHEHSQFCMSGDHTLEGTEHAIKDITTEEADEYFVIILSDANLSRYGINPARFAQILTSDPQVNAFAIFIGSLGDQAARLQRTLPAGRSFIAMDTKKIPQILQQIFTSTMLSSI
Protein: E1 ubiquitin-activating enzyme (EC 6.2.1.45) (Ubiquitin-activating enzyme E1) (Q8T0L3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-conjugating enzyme E2-22 kDa
- FI11905p
- Ubiquitin-conjugating enzyme E2-17 kDa
- Ubiquitin-conjugating enzyme E2-17 kDa
- Ubiquitin-conjugating enzyme E2 N
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-conjugating enzyme E2 C
- Ubiquitin-conjugating enzyme E2 S
- E2 ubiquitin-conjugating enzyme
Sequence:
MSSGQQLMADSPACSSSDHSPLAKKRRLELLGDGVGAMGMEEEEAGGATSSSSSNNYENHDKAGGVDISGKCQSKTTSEHQLELCVSSSTSDTCGVNAAAKRAEKQKLKQSQGSGDDVSTSSAVEKEGSKRPEKRNYLNTTTIESQEASSSASATSNSNNNVSSSNNNSNNSTNNRQLEGSSNMAGNSAAAGGDIDESLYSRQLYVLGHDAMRRMANSDILLSGLGGLGLEIAKNVILGGVKSITLHDTATCGLHDLSSQFYLTEADIGKNRAEASCAQLAELNNYVRTVSHTGPLTEEFLRKFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPISTMIASITHDAQGVVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTFSIGDTSKFGEYKSGGVATQVKMPKTISFKPLAQATEEPEFLISDFAKLDSPATLHVAFNALSCYRKAHNGALPRPWNEEDANSFLEVVRASSNAEVDEKLVLQFAKICSGNTCPLDAAVGGIVAQEVLKACSGKFTPIYQWLYFDALECLPTEGVEEADAQPVGSRYDSQIAIFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPLEILDSIKKALIDDKPKSFAHCVEWARLYWEDQYVNQIKQLLFNFPPDQITSSGQPFWSGPKRCPDPLVFDVNDPMHLDFIYAAANLRAEVYGIEQVRNRETIAELVQKVKVPEFKPRSGVKIETNEAAAAASANNFDDGELDQDRVDKIISELLKNADKSSKITPLEFEKDDDSNLHMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIATTTSVLSGLAVLEVIKLIVGHRDLVKFKNGFANLALPFMAFSEPLPAAKNTYYGKEWTLWDRFEVTGELSLQEFLNYFEENEKLKITMLSQGVSMLYSFFMPKAKCSERLPLPMSEVVRRVSKRRLEPHERSLVFEICCNDVDGEDVEVPYVRYTLP
Protein: Outer membrane protein B (Q9Z752)
Organism: Chlamydia pneumoniae (Chlamydophila pneumoniae)
Subcellular location: Cell outer membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Major outer membrane porin
- Large cysteine-rich periplasmic protein OmcB
- Porin AaxA
Sequence:
MNSKMLKHLRLATLSFSMFFGIVSSPAVYALGAGNPAAPVLPGVNPEQTGWCAFQLCNSYDLFAALAGSLKFGFYGDYVFSESAHITNVPVITSVTTSGTGTTPTITSTTKNVDFDLNNSSISSSCVFATIALQETSPAAIPLLDIAFTARVGGLKQYYRLPLNAYRDFTSNPLNAESEVTDGLIEVQSDYGIVWGLSLQKVLWKDGVSFVGVSADYRHGSSPINYIIVYNKANPEIYFDATDGNLSYKEWSASIGISTYLNDYVLPYASVSIGNTSRKAPSDSFTELEKQFTNFKFKIRKITNFDRVNFCFGTTCCISNNFYYSVEGRWGYQRAINITSGLQF
Protein: Fructose-1,6-bisphosphatase (FBPase) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase) (P09201)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- ATP-dependent 6-phosphofructokinase subunit alpha
- Phosphoenolpyruvate carboxykinase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Transketolase 1
- Transketolase 2
- Transaldolase
- GID complex substrate-recognition subunit 4
- ATP-dependent 6-phosphofructokinase subunit beta
- Transaldolase NQM1
Sequence:
MPTLVNGPRRDSTEGFDTDIITLPRFIIEHQKQFKNATGDFTLVLNALQFAFKFVSHTIRRAELVNLVGLAGASNFTGDQQKKLDVLGDEIFINAMRASGIIKVLVSEEQEDLIVFPTNTGSYAVCCDPIDGSSNLDAGVSVGTIASIFRLLPDSSGTINDVLRCGKEMVAACYAMYGSSTHLVLTLGDGVDGFTLDTNLGEFILTHPNLRIPPQKAIYSINEGNTLYWNETIRTFIEKVKQPQADNNNKPFSARYVGSMVADVHRTFLYGGLFAYPCDKKSPNGKLRLLYEAFPMAFLMEQAGGKAVNDRGERILDLVPSHIHDKSSIWLGSSGEIDKFLDHIGKSQ
Protein: Stromal cell-derived factor 1 (C-X-C motif chemokine 12) (Q8AV10)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Atypical chemokine receptor 3b
- C-X-C chemokine receptor type 4b
- Chemokine
- Atypical chemokine receptor 3a
- Chemokine
- Chemokine
- C-C motif chemokine 21
- Chemokine
- Chemokine
- C-X-C chemokine receptor type 2
Sequence:
MDLKVIVVVALMAVAIHAPISNAKPISLVERCWCRSTVNTVPQRSIRELKFLHTPNCPFQVIAKLKNNKEVCINPETKWLQQYLKNAINKMKKAQQQQV
Protein: Glutathione hydrolase proenzyme (EC 2.3.2.2) (EC 3.4.19.13) [Cleaved into: Glutathione hydrolase large chain; Glutathione hydrolase small chain] (O25743)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Interaction partners:
- Glutamine synthetase
- L-glutamate gamma-semialdehyde dehydrogenase
- Cytosol aminopeptidase
- NADP-specific glutamate dehydrogenase
Sequence:
MRRSFLKTIGLGVIALFLGLLNPLSAASYPPIKNTKVGLALSSHPLASEIGQKVLEEGGNAIDAAVAIGFALAVVHPAAGNIGGGGFAVIHLANGENVALDFREKAPLKATKNMFLDKQGNVVPKLSEDGYLAAGVPGTVAGMEAMLKKYGTKKLSQLIDPAIKLAENGYAISQRQAETLKEARERFLKYSSSKKYFFKKGHLDYQEGDLFVQKDLAKTLNQIKTLGAKGFYQGQVAELIEKDMKKNGGIITKEDLASYNVKWRKPVVGSYRGYKIISMSPPSSGGTHLIQILNVMENADLSALGYGASKNIHIAAEAMRQAYADRSVYMGDADFVSVPVDKLINKAYAKKIFDTIQPDTVTPSSQIKPGMGQLHEGSNTTHYSVADRWGNAVSVTYTINASYGSAASIDGAGFLLNNEMDDFSIKPGNPNLYGLVGGDANAIEANKRPLSSMSPTIVLKNNKVFLVVGSPGGSRIITTVLQVISNVIDYNMNISEAVSAPRFHMQWLPDELRIEKFGMPADVKDNLTKMGYQIVTKPVMGDVNAIQVLPKTKGSVFYGSTDPRKEF
Protein: L-lysine 4-hydroxylase (EC 1.14.11.-) (Alpha-ketoglutarate-dependent dioxygenase) (KDO3) (L-lysine hydroxylase) (A5FF23)
Organism: Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / BCRC 14874 / CCUG 350202 / NBRC 14942 / NCIMB 11054 / UW101) (Cytophaga johnsonae)
Function: Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-lysine, leading to (4R)-4-hydroxy-L-lysine. To a lesser extent, can also use (3S)-3-hydroxy-L-lysine as substrate, producing the dihydroxylated product (3R,4R)-3,4-hydroxy-L-lysine. Cannot use D-lysine or L-ornithine as substrate.
Interaction partners:
- AMP-dependent synthetase and ligase
- IucA aerobactin siderophore synthesis-like protein
- Carrier domain-containing protein
- Nonribosomal peptide synthetase
- IucC aerobactin siderophore synthesis-like protein
- Pyridoxal-dependent decarboxylase
Sequence:
MKSQSLIEDEIPVKENYAYQIPTSPLIVEVTPQERNILSNVGALLEKAFKSYENPDYIEALHLYSFQLLPERIARILSRFGTDFSADQYGAIIFRGLLEVDQDHLGPTPANWQSADYSKLNKYGFICSLLHGAVPSKPVQYYAQRKGGGILHAVIPDEKMAATQTGSGSKTNLYVHTEDAFLLHQADFLSFLYLRNEERVPSTLYSVRSHGKVNKIMEKLFDPIYQCPKDANYQEEINDGPLASVLYGNKKLPFIRFDAAEQIFNENAGQTPEALYNLTEFWNEAKELINSDYIPDSGDVIFVNNHLCAHGRSAFTAGQKEENGKLVPCERRQMLRMMSKTSLIHIRSMTHTDDPYFVMEEHLGKVFDQA
Protein: K+/Cl-Cotransporter (Potassium chloride cotransporter isoform b) (G5EEC9)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSGGRFRVQSVADGGGGGAGSVGALDSVSDSNLAVNSATKKENEGAERIPLCEQHSPLALYEQDYDTQGQKIGTMLRKLSVYNATEATSVEADEKPKAAAAKMGTIMGVFLPCLQNIFGVLFFIRLAWIIGTAGVFQAFFVVLTCVSVTFLTSISLSAIATNGVVPSGGPYYMISRNLGPELGGAVGILFYLGTTIAASMYITGAIEILLLYIYPQAKLFDDIYHNFRVLGTVLLLILGLIVMAGVKFVNRCALPLVIVVILCILSAILGVFVRYDGSDSLKFCMVGDRPVDLSTYFEKTQVQPNCTADGLQDLFCSTNGTCDHYYDRMKNIKVWKSSGMPAIREERAIKGIASGVFFDNLWPKYLRAGEVLSKDRKDKGDLNRGGHPSYIYAESVTNFMILVGVFFPSATGIMAGSNRSGNLRDAAKSIPLGTLAAQNFSSFIYLLGVVLFGASVSEMFIRDKYGRSAMGKLIISEISWPFPQVILFGCFMSTAGAGMQSLTGAPRLLQAIAADDVLPFLKPFRKMDSRGEPIRAILLTLAICECGILIAVIENITALITQFFLMCYLGVNAACALQSLLKSPGWRPGFRYFHWSLSMIGAILCVAVMFISAWHFALFAIIIGAGVYKYIEYAGAEKEWGDGLRGLGLSAARFALLNLDDKPQHSRNWRPQLLVLAPDVESANTNGILSFVSQLKAGKGLTLVAHCMEGEYADNYLKAQAVQEKLKAVVKKNKIKGFCDVLVTSNVIEGISCLVQTSGLGGMRHNTVVLSWPNDWKAEQEWVVANKFVSAIRAISAAKCAIMVPKYAEKFPANGTKVSGFIDVWWVVHDGGLLMLLPFLLRQHKTWKNTTVRLFAIAQMEDNNVQMKTDLEKFLYHLRIDAAVNVIEMTDSDISDYTYERTMKMEERNQYLKNLNKSDRDKDIQNHLEIVTRERKLSRINEEAPAVVPEQRNLEVVDEEQEDGKSENGSAKIEHKGVRFSDDEDSKEVKVGNGTLERDREERQRKRRYNVHKMHTAVKLNELMRQKSSDAQLVFVNLPGPPDADSDSYYMDFIEALTEGLDRVLLVRGTGAEVVTIYS