wanglab/gogpt-training-data huggingface dataset:
Protein: Putative tyrosine-protein kinase YveL (EC 2.7.10.2) (P71051)
Organism: Bacillus subtilis (strain 168)
Interaction partners:
- Uncharacterized protein YveK
- Probable capsular polysaccharide biosynthesis protein YwqC
- Probable polysaccharide biosynthesis protein EpsC
- Putative glycosyltransferase EpsE
- Tyrosine-protein phosphatase YwqE
- Uncharacterized sugar transferase EpsL
- Putative glycosyltransferase EpsD
- Putative pyridoxal phosphate-dependent aminotransferase EpsN
- Putative glycosyltransferase EpsF
- Putative pyruvyl transferase EpsO
Sequence:
MIFRKKKARRGLAQISVLHNKSVVAEQYRTIRTNIEFSSVQTNLRSILVTSSVPGEGKSFSAANLAAVFAQQQEKKVLLVDADLRKPTINQTFQVDNVTGLTNVLVGNASLSETVQKTPIDNLYVLTSGPTPPNPAELLSSKAMGDLISEIYEQFSLVIFDSPPLLAVADAQILANQTDGSVLVVLSGKTKTDTVLKAKDALEQSNAKLLGALLNKKKMKKSEHYSY
Protein: Kunitz-type serine protease inhibitor RsTIQ2 (P84554)
Organism: Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)
Function: Serine protease inhibitor. Inhibits trypsin, elastase, plasmin and kallikrein.
Interaction partners:
Sequence:
EAVDFDSQCVPTADPGKCKFYFPMWNVNVFT
Protein: Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30) (Q3UN04)
Organism: Mus musculus (Mouse)
Function: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy. Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signaling. Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (By similarity). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:24513856}.
Interaction partners:
- Ubiquitin-ribosomal protein eS31 fusion protein
- Polyubiquitin-B
- Polyubiquitin-C
- Ubiquitin-ribosomal protein eL40 fusion protein
- Mitochondrial import receptor subunit TOM20 homolog
- ubiquitinyl hydrolase 1
- Mitochondrial ubiquitin ligase activator of NFKB 1
- Mitochondrial Rho GTPase 1
- Zinc finger-containing ubiquitin peptidase 1
- Mitochondrial import receptor subunit TOM70
Sequence:
MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTRGSPHPTTNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEARGTLTGEKVEHQRSTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKATENPGSAPEVQDAQAAPKPGLSQPGAPKTQIFLNGACSPSLLPALPSPVAFPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRSEE
Protein: Nimrod C1, isoform A (Q9VJU5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSHIQCLWVCLGFFMLLVDFIQPIGLNVCNRSQVVTYKRYVERSRVIPYQHRSFWSGWQTKYRTEYYTDEETAYRTVMRPSCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGGIDCHPVCPTVCGKNEFCDRPGVCSCQNGYKRTSPSDNCLPVCEKECGHHSFCSEPGKCECEPGYEKVGNGTVFPDGYKNNSNGNCSPICPKDCGQNSRCVRPGVCECENGYAGDDGGTNCRPVCSTCPENGLCLSPGVCVCKPGYVMRNDLCQPHCEKCSDNAHCVAPNQCECFPGYESSGADKKCVPKCSKGCTNGFCFAPETCVCSIGYQMGPNQVCEPKCSLNCVHGKCTSPETCTCDPGYRFKDNSHHECDPICDSGCSNGHCVAPNFCICHDGYQLNSTNPVTSMCQPICKGCQFGDCVAPNVCECNVGYENINGLCELQTTTDSYEYSTTTVELQSSTVDPQLQTSTSEVPHSNCTAGCMCWIEYDGMGTFNTAKCAKICVDPQDKPCLNLDNCQCDLSSGQLVCQEDSDMDYSGENSRYVCHILPEQGARSEAEVRIPDRTGSSNKWMIIVGSCAGMIIGVAATIIGIKYYRRSTSRRNFEAEEAIVECDFE
Protein: SKP1 component POZ domain-containing protein (Q382K3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAACDVTLVSPNGETVSIPAASAWNHIGLLQRLAELDESGCTEMPEIELGFSTEVLRAVADYLEKSSRFVIDARRPLTGSLRDFVPEWNLDFVRGAERREILMPLFECACFLCVVELRELLGAYVAERVNEIAKEAPSIMEGAARLRTYLQLENEWTEEETEHLEQEMRYAKQVDPFAY
Protein: Taxoid 14-beta-hydroxylase (EC 1.14.13.146) (Taxane 14b-hydroxylase) (Q84KI1)
Organism: Taxus cuspidata (Japanese yew)
Function: Catalyzes the conversion of 5-alpha-acetoxy-10beta-ol to 5-alpha-acetoxy-10beta,14beta-dihydroxy taxadiene. Also acts on taxa-4(20),11-dien-5-alpha-yl acetate.
Subcellular location: Microsome membrane {ECO:0000269|PubMed:12729625}; Multi-pass membrane protein {ECO:0000269|PubMed:12729625}.
Interaction partners:
Sequence:
MDVFYPLKSTVAKFNECFPAILFIVLSAVAGIVLPLLLFLRSKRRSSVGLPPGKLGYPFIGESLLFLKALRSNTVEQFLDERVKNFGNVFKTSLIGHPTVVLCGPAGNRLILANEEKLVQMSWPKSSMKLMGEKSITAKRGEGHMIIRSALQGFFSPGALQKYIGQMSKTIENHINEKWKGNDQVSVVALVGDLVFDISACLFFNINEKHERERLFELLEIIAVGVLAVPVDLPGFAYHRALQARSKLNAILSGLIEKRKMDLSSGLATSNQDLLSVFLTFKDDRGNPCSDEEILDNFSGLLHGSYDTTVSAMACVFKLLSSNPECYEKVVQEQLGILSNKLEGDEITWKDVKSMKYTWQVVQETLRLYPSIFGSFRQAITDIHYNGYIIPKGWKLLWTPYTTHPKEMYFSEPEKFLPSRFDQEGKLVAPYTFLPFGGGQRSCPGWEFSKMEILLSVHHFVKTFSTFTPVDPAEIIARDSLCPLPSNGFSVKLFPRSYSLHTGNQVKKI
Protein: Nuclear export protein (NEP) (Non-structural protein 2) (NS2) (A4ZNR2)
Organism: Influenza A virus (A/lvPR8/34(H1N1))
Subcellular location: Virion {ECO:0000256|HAMAP-Rule:MF_04067, ECO:0000256|RuleBase:RU362104}. Host nucleus {ECO:0000256|HAMAP-Rule:MF_04067, ECO:0000256|RuleBase:RU362104}.
Interaction partners:
Sequence:
MDPNTVSSFQDILLRMSKMQLESSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNEKWREQLGQKFEEIRWLIEEVRHKLKITENSFEQITFMQALHLLLEVEQEIRTFSFQLI
Protein: Cell division control protein 73 (RNA polymerase-associated protein CDC73) (Q06697)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II. Also has a role in transcription-coupled histone modification. Required for activation of RAD6 ubiquitin conjugate and the BRE1 ubiquitin ligase which ubiquitinate 'Lys-126' histone H2B. Activates the SET1 histone methyltransferase complex for methylation of 'Lys-4' of histone H3 and for methylation of 'Lys-73' of histone H3 by DOT1 and 'Lys-36' of histone H3 by SET2.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:15643076, ECO:0000269|PubMed:9032243}.
Interaction partners:
- Antiviral protein SKI8
- FACT complex subunit POB3
- RNA polymerase-associated protein RTF1
- Transcription elongation factor SPT5
- RNA polymerase II-associated protein 1
- RNA polymerase-associated protein CTR9
- RNA polymerase-associated protein LEO1
- FACT complex subunit SPT16
- CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4
- DNA-directed RNA polymerase II subunit RPB1
Sequence:
MANSLDRLREHLKNGDKLVLKNNEGQSTDDITKATMVETLSSDGSTQDSFPLNEETEIEIDGSLVQLRIIVHCWMNKDSSAADYLADCQNKQLTNVSFLQRTDLINWLSGNTESSQYLKAPGQKGETSDKVDIENKTLAGELSTVKSTTSASLENDSEVSDPVVVETMKHERILVDHNSALRGAKPINFGYLIKDAELKLVQSIKGSLRGSKLPPGHKGAHGRISKTNGSSGGPRKDPIILIPSAASSILTVANIKQFLLESKYVNPRNLPSVPNGLVNIEKNFERISRPIRFIIVDNTRMFTKPEYWDRVVAIFTTGHTWQFNNYQWNSPQELFQRCKGYYFHFAGDSVPQHVQQWNVEKVELDKNKRFKDVEVVRYFWHSLEKELISRGYR
Protein: Lethal (3) neo38, isoform G (Lethal (3) neo38, isoform J) (A0A0B4K6S1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MQYGQNISIPYSQPQGDLNFLNAAAAADHKVLNQQILQNVNQSWQTLANTANTVDYSSHLLSATLPISIQHFLKYSETIKKESTGDVLKNGTNLASLALGGVALTPSNNGANGGHHNGLVGMDHGGHMTNMTDANGAALTNGASNGVNGNANGTVTNGGAGAVSSSGSVGTTNASGGTGTASGKKTKKKKPPKEKKPRPKPGEIRETKALDGSTLYCCPECQMAYPDRSLIEQHVISHAVERRFVCDICNAALKRKDHLTRHKLSHIPDRPHVCNICMKSFKRKEQLTLHIVIHSGEKKHVCIECGKGFYRKDHLRKHTRSHIARRVKSEVSAQNVNGSAGGGGGGGGGNSAQSNALHGS
Protein: Alpha-mannosidase (EC 3.2.1.-) (Q9VKV2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MINVHLVPHSHDDVGWLKTVDQYYYGSQNKIQHAGVQYILDTVVEELLKDSSRRFIQVETFFFAKWYSEQTETVQRAVKKLVAQGRLEFAGGAWSMNDEATVHYQSVVDQFNLGLRYLKDTFGDCGRPTVGWQIDPFGHSREMASIFAQMAFNGEFFARMDYVDKKQRMLDLEMEMIWQSSESLKNSNIFTGMLYNHYSAPPGFCFDINCEDAPIIDGESYDNNVDARVSEFIDYVKNMSKSYRSTHIMVPMGDDFQYEDAAVNFKNMDKLIKYVNDRQSTGSQVNVFYSTPSCYLYELHQLKQTWPNKTEDFFPYSSDSHSYWTGYFTSRPTQKRFHRDGNHFFQTVKQLSVLANLSGTQYSEDLDNLSQAMGIMQHHDAVTGTEKQAVASDYDRLLFKAIVGAENSARDALRSLTNLTSGEFESCLELNISVCAFTQDTANNVIVTLVNPLAHSSTQYVRVPAKNENYIVTDEKGREVFSEVVPVPWQVLALEHRPNDTQHELVFEASVDKIANFLIRVLPSPKNIAEDQVQFPVERSQDELTVETSLVKLTFDTTTGGLKTVKMNGFTENIQQTFGIYKGYRGNNGESKNRSSGAYVFRPYGDIEIVNNKVELSFYNGTKVKEVHQHVNEWISQVIRIYEDVNRVEFEWLVGPIPTDDDVGKEIITRFSSNISSKGKFYTDSNGREILERERNQREHFTPDMSEAISGNYYPVTGQISLQDDEKRITLLNDRAQGGTSLKDGELELMLHRRLLNDDAFGVGEALNETQYGTGLIARGKIYLILDAVDGKPNQRLLQHQLDQHFWKFFSKSNGVASVNRNMIPDFFGIPESVELLSLEPYSKDQILIRLENFNTEGNVVSFNIYPLFESLDGYQIWETTLDGNMLLEDVKRFKFAQDGTGSIPSSVEYYHAPHNPLTANSTMNASGFVVTLVPMQIRTFIIQQKYIPS
Protein: Ubiquitin-like-specific protease 2 (EC 3.4.22.-) (P40537)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Insertion mutation in SMT4 confers temperature and benomyl sensitivity; high copy suppressor of a temperature sensitive mutation in MIF2.
Interaction partners:
- Ubiquitin-like protein SMT3
- Ubiquitin-like-specific protease 1
- SUMO-conjugating enzyme UBC9
- Monopolin complex subunit CSM1
- Ubiquitin-activating enzyme E1-like
- E3 SUMO-protein ligase SIZ1
- E3 SUMO-protein ligase SIZ2
- DNA damage tolerance protein RHC31
- E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5
- E3 SUMO-protein ligase MMS21
Sequence:
MSARKRKFNSLKPLDTLNSSRASSPRSSASLPPKRYNTFRKDPKIVDHLNNASTKDFLPVLSMNSESKRQIELSDNDVDNNDEGEGVNSGCSDQDFEPLQSSPLKRHSSLKSTSNGLLFQMSNNLGNGSPEPAVASTSPNGSIISTKLNLNGQFSCVDSKTLRIYRHKAPCIMTFVSDHNHPKFSLYFQQSVIYNSQVNLLDDVELIILDKKNSFMAIILKDLKKVKMILDVNNSSININTNILIWSTASSASNKKIKSIKRFLLMSYSSSIKVEILDHKEQILERLKHLIHPISSSSPSLNMERAINSTKNAFDSLRLKKTKLSTNDDESPQIHTHFLSNKPHGLQSLTKRTRIASLGKKEHSISVPKSNISPSDFYNTNGTETLQSHAVSQLRRSNRFKDVSDPANSNSNSEFDDATTEFETPELFKPSLCYKFNDGSSYTITNQDFKCLFNKDWVNDSILDFFTKFYIESSIEKSIIKREQVHLMSSFFYTKLISNPADYYSNVKKWVNNTDLFSKKYVVIPINISYHWFSCIITNLDAILDFHQNKDKNDAINSDEISINNPLVNILTFDSLRQTHSREIDPIKEFLISYALDKYSIQLDKTQIKMKTCPVPQQPNMSDCGVHVILNIRKFFENPVETIDVWKNSKIKSKHFTAKMINKYFDKNERNSARKNLRHTLKLLQLNYISYLKKENLYEEVMQMEEKKSTNINNNENYDDDDEEIQIIENIDQSSKDNNAQLTSEPPCSRSSSISTTEREPTELHNSVVRQPTGEIITDNEDPVRAASPETASVSPPIRHNILKSSSPFISESANETEQEEFTSPYFGRPSLKTRAKQFEGVSSPIKNDQALSSTHDIMMPSPKPKRIYPSKKIPQLSSHVQSLSTDSMERQSSPNNTNIVISDTEQDSRLGVNSESKNTSGIVNRDDSDVNLIGSSLPNVAEKNHDNTQESNGNNDSLGKILQNVDKELNEKLVDIDDVAFSSPTRGIPRTSATSKGSNAQLLSNYGDENNQSQDSVWDEGRDNPILLEDEDP
Protein: Kinetochore-associated protein NNF1 (P47149)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules. NNF1 is required for a number of nuclear functions. Cells depleted of NNF11 or containing a temperature-sensitive NNF1 mutation have elongated microtubules and become bi- and multinucleate. They also have a fragmented nucleolus and accumulate poly(A)+ RNA inside the nucleus.
Subcellular location: Nucleus {ECO:0000269|PubMed:12455957}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:12455957, ECO:0000269|PubMed:14657030}. Note=Associated with the kinetochore (PubMed:12455957, PubMed:14657030).
Interaction partners:
- Kinetochore-associated protein DSN1
- Kinetochore-associated protein NSL1
- Kinetochore-associated protein MTW1
- Inner kinetochore subunit AME1
- Outer kinetochore KNL1 complex subunit SPC105
- Kinetochore protein NUF2
- Inner kinetochore subunit MCM21
- Inner kinetochore subunit CTF19
- Kinetochore protein SPC25
- Histone H3-like centromeric protein CSE4
Sequence:
MVNSHGIRYIRLKQVFNRALDQSISKLQSWDKVSSCFPQYVNSKQGAINVANCQRQLTEFWTELCQREFKEIMEERNVEQKLNELDELILEAKERYTDRDQDEVNKGPAIDELSSKELVECHLYSQRMHAIHEIDERLAKVNEMNDQLAQELKDLETQVEVEKNEIGKMYDEYLGSHTDQPANVLLVQSLNDMVLELKENY
Protein: NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1) (O60285)
Organism: Homo sapiens (Human)
Function: Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1. May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53. May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1. Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR. Regulates UV radiation-induced DNA damage response mediated by CDKN1A. In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:21317932}. Cytoplasm {ECO:0000269|PubMed:21317932}.
Interaction partners:
- Serine/threonine-protein kinase STK11
- Ubiquitin carboxyl-terminal hydrolase 9X
- Cellular tumor antigen p53
Sequence:
MEGAAAPVAGDRPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEVMLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGVVGPALPSTFKMEQDLCRTGVLLPSSPEAEVPGKLSPKQSATMPKKGILKKTQQRESGYYSSPERSESSELLDSNDVMGSSIPSPSPPDPARVTSHSLSCRRKGILKHSSKYSAGTMDPALVSPEMPTLESLSEPGVPAEGLSRSYSRPSSVISDDSVLSSDSFDLLDLQENRPARQRIRSCVSAENFLQIQDFEGLQNRPRPQYLKRYRNRLADSSFSLLTDMDDVTQVYKQALEICSKLN
Protein: Appr-1-p processing enzyme family protein (At1g69340/F10D13.28) (Q94JV1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- 2-oxoglutarate
- Protein LURP-one-related 4
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH8
- At4g36640
- Sec14p-like phosphatidylinositol transfer family protein
- At4g08690
- At1g55840/F14J16_2
- SEC14 cytosolic factor family protein / phosphoglyceride transfer family protein
- Transmembrane protein
- AT1G14820 protein
Sequence:
MMYQTIPTAPTIRGGTPTESGDYVVTLDQIPRWSDVEQRSSLEDETGDPEHSNPRYANPLASSSEAGSSGNGMVSKFPVDHEINSRIYLWRGEPWNLEVDAVVNSTNENLDEAHSSPGLHVAAGPGLAEQCATLGGCRTGMAKVTNAYDLPARRVIHTVGPKYAVKYHTAAENALSHCYRSCLELLIDSGLQSIALGCIYTEAKNYPREPAAHVAIRTVRRFLEKQKDKISAVVFCTTTSSDTEIYKRLLPLYFPRDEHEEEVAISKLPADVGDENGETVIDERKIRIQALPNKPPPRSFPTPLERPSTDLTLLRRNSNHLDSYLDPAFMSLIKDPDERRKEQWEKTAQAQSGFNFVKLLGFGDLGGPPLSAAEEYSLHSRYLAKANSINLSEIAEMKIVYRGGVDTEGHPVMVVVGAHFLLRCLDLERFVLYVIKEFEPVIQKPYSIVYFHSAASLQVQPDLGWMKRLEQILGRKHQRNLQAIYVLHPTFHLKATILTMQFFVDNVVWKKVVYADRLLQLFKYVPREQLTIPDFVFQHDLEVNGGKGLIVDPRTKYVYQRP
Protein: Probable glutamate carboxypeptidase VP8 (EC 3.4.17.21) (Protein VIVIPAROUS8) (Protein WIDOW'S PEAK 1) (A0A1D6L709)
Organism: Zea mays (Maize)
Function: Involved in the regulation of meristem development and seed maturation processes. Mediates regulation of embryonic regulatory genes and genes controlling abscisic acid (ABA) biosynthesis and turnover in developing seeds. May be required for the synthesis of small signaling molecules that integrates meristem and embryo formation in seeds.
Subcellular location: Cell membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MPHSVLARLPPGSVRLVAAFGLLLLVSLLVLHRRPGRPHVAAAAASDRLTDPSRSRLFLSQSPGANASIAADLRALTAGPHLAGTPASAGAAAHVLARLRAAGLQTLTREYEPLLSYPGHASLALLRPDGSLLARLSLEEPADEGRRVVPPYHAYAPSGGAVAEAVFVNLGREEDYVVLERLGVGVRGRVAVARRGGGYRGGVVARAADKGAVAVLIAGNADGGVERGVVLLGGPGDPLTPGWAATSGAERLKFDDKAVKQRFPSIPSMPVSAKTAAAIIRSLGGPAIPAEWKDGLGVDTGGLGPGPTLVNFTYQEDRKFYKIRDIFGIIKGQEEPDRYVILGNHRDAWTYGAVDPNSGTAALLDIARRLGIMLQSGWKPRRSIILCSWDGEEFGMIGSTEWVEDNLEDLHSKAVAYLNVDCAVQGVGFFAGSTPQLDKLLVDITRQVRDPDVTGKMVHDTWNEMSGGIKIERLARTDSDFAPFLHHAGIPSVDLYYGEEFPGYHTALDTYNWMEKHGDPFFLRHLAITEIWGLLALRLANDPVLPFDYQAYTSQLQEHIKTLSALTSNGHAVNLMNGCVNDLSGAAMEVLKEMKKLQQMDLYDEHARMRRRLLNDRLLLAERSFLQPEGLQGRGWFKHLLYSPPEDYESKLSFFPGIADAISRSANLSDKEQEVAMQHEVWKVCRAIQRAASVLRGEFSEQKPTNFSSLVTP
Protein: Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48) (Q86UV5)
Organism: Homo sapiens (Human)
Function: Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16214042}. Nucleus {ECO:0000269|PubMed:16214042, ECO:0000269|PubMed:36293380}. Cell projection, cilium {ECO:0000269|PubMed:36293380}.
Interaction partners:
- TNF receptor-associated factor 2
- Ubiquitin-like modifier-activating enzyme 6
- Nucleoporin NUP188
- Ubiquitin carboxyl-terminal hydrolase 5
- Ubiquitin carboxyl-terminal hydrolase isozyme L3
- Ubiquitin carboxyl-terminal hydrolase 13
Sequence:
MAPRLQLEKAAWRWAETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCKGNPNCLVGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNHACLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKECVVERCRILRLKNQLNEDYKTVNNLLKAAVKGSDGFWVGKSSLRSWRQLALEQLDEQDGDAEQSNGKMNGSTLNKDESKEERKEEEELNFNEDILCPHGELCISENERRLVSKEAWSKLQQYFPKAPEFPSYKECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPEDTDVLYIVSQFFVEEWRKFVRKPTRCSPVSSVGNSALLCPHGGLMFTFASMTKEDSKLIALIWPSEWQMIQKLFVVDHVIKITRIEVGDVNPSETQYISEPKLCPECREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILSDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH
Protein: Alanine- and arginine-rich domain-containing protein (Q4LEZ3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGPGDFRRCRERISQGLQGLPGRAELWFPPRPACDFFGDGRSTDIQEEALAASPLLEDLRRRLTRAFQWAVQRAISRRVQEAAAAAAAREEQSWTGVEATLARLRAELVEMHFQNHQLARTLLDLNMKVQQLKKEYELEITSDSQSPKDDAANPE
Protein: p44-87 outer membrane protein, truncated (Q2GLI4)
Organism: Anaplasma phagocytophilum (strain HZ)
Interaction partners:
Sequence:
VEISHSEIDGKVCKTKSAGTGKNPCDHSQKPCSTNAYYARRTQKSRSSGKTSLCGDSGYSGQELITGGHYSSPSVFRNFVKDTLQGNGSENWPTSTGEGSESNDNAIAVAKDLVNELTPEERTIVAGLLAKIIEGSEVIEIRAISSTSVTMNICSDITISNILMPYVCVGPGMSFVSVVDGHTAAKFAYRLKAGLSYKFSKEVTAFAGGFYHHVIGDGVYDDLPLRHLSDDISPVKHAKETAIARFVMRYFGGEFGVRLAF
Protein: Peroxidase 3 (Atperox P3) (EC 1.11.1.7) (ATPRC) (RCI3A) (Rare cold-inducible protein) (O23044)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000255|PROSITE-ProRule:PRU00297}.
Interaction partners:
- Potassium transporter 5
- AT5g45310/K9E15_9
- Monolignol oxidoreductase AtBBE-like 13
- Pentatricopeptide repeat-containing protein At3g22670
- UDP-glycosyltransferase 72E3
- UDP-glycosyltransferase 72E2
- Cytochrome P450 84A1
Sequence:
MNCLIAIALSVSFFLVGIVGPIQAQLQMNFYANSCPNAEKIVQDFVSNHVSNAPSLAAALIRMHFHDCFVRGCDGSVLINSTSGNAERDATPNLTVRGFGFIDAIKSVLEAQCPGIVSCADIIALASRDAVVFTGGPNWSVPTGRRDGRISNAAEALANIPPPTSNITNLQTLFANQGLDLKDLVLLSGAHTIGVSHCSSFTNRLYNFTGRGGQDPALDSEYAANLKSRKCPSLNDNKTIVEMDPGSRKTFDLSYYQLVLKRRGLFQSDSALTTNPTTLSNINRILTGSVGSFFSEFAKSMEKMGRINVKTGSAGVVRRQCSVANS
Protein: Omp-1N (Q2GIQ0)
Organism: Anaplasma phagocytophilum (strain HZ)
Interaction partners:
Sequence:
MVFGSLRCLFFTYCLLVSFCLVERGEAGGFYASLGWGESVVDFGVEHLKVRGITGSVMGPRKSELDAVKYGHDTFSKGIGGVGSGEFGDKYRPVYTEDFGLSGSFGYRFGNLGIEIEGSEQEFHPSAAGYKIEGNAVHFAFTTGKSGAKGEVSGFVGENPGMHLGLVLLNGCYSGLRLDEKNGIYSCLGLGLAATDYLGGLGRLRALWNAKIGVELQFTKNLTMFGEVYYRGFGVLRGKVRVFSVAAVEGVDTLLSSGMNVSYVGNACGVRYLF
Protein: Ectodysplasin A (HCG14664) (A0A0C4DGX3)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKIAVKMVHADISINMSKHTTFFGAIRLGEAPAS
Protein: Molybdenum transport system permease protein ModB (P0AF01)
Organism: Escherichia coli (strain K12)
Function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Molybdate-binding protein ModA
- Molybdenum import ATP-binding protein ModC
- Sulfate/thiosulfate import ATP-binding protein CysA
- Glutamine transport ATP-binding protein GlnQ
- DNA-binding transcriptional dual regulator ModE
- L-cystine transport system ATP-binding protein TcyN
- sn-glycerol-3-phosphate import ATP-binding protein UgpC
- Lipopolysaccharide export system ATP-binding protein LptB
- Glutamate/aspartate import ATP-binding protein GltL
- Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZ
Sequence:
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
Protein: Cationic amino acid transporter C-terminal domain-containing protein (Q54EJ9)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MASYLNRSSEQQNIPLLKNRKIYSLNSLIRKYPVNGFQDDDDNNNQQTNNGEGNLNKCLTVFDIISYGIGSTVGAGVFVSIGIAISSYAGPGTLLSFLFSAIACLISAFCYSEFSARIPASGSAYTFAYVSLGEYMGWFVGWNLTLEYAISASAVARGWVGYFSVIFSIFGAKTPQFIQGYQINDWININPIAPLIIVFCTIILVFGIKDSARFNMIITCINILTILFFIVLGSIYVKVENWTPFLPFGFDGVFNACSVVFFSYVGFDSVTTLAGEVKNPKRDLPIGVIGSLVIATSLYIGVTLVLSGMVNFREVSQGSPLSDAFIHNGLDMKWAAMIIAFGTLTSLTASTLCCLIGQPRIYLQMAKDGLFFKKFGELNKKQVPVFGILFTCGFASLLAIVLDLDNLTNMISIGTLLAFTCVCAGVVVMRYRNEDGSENGPIPSTLVLFVLFVVACVFGAASYNGWKIWIQIVLAVIQLALIILLCFKKQTLDKSTCNYFLCPLVPIIPCLGIIINTYFIMHLDSASFIRMAIWTVVGTIVYFVYSIRNSKLNNTNNNSYIN