wanglab/gogpt-training-data huggingface dataset:
Protein: Iron-sulfur cluster assembly 1 homolog, mitochondrial (Lethal (1) G0136) (Putative magnetoreceptor subunit MagR) (Q8T3X9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity). Required for maintenance of circadian rhythms under constant darkness.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9BUE6}.
Interaction partners:
- Iron-sulfur cluster assembly 2 homolog, mitochondrial
- Iron-sulfur cluster assembly enzyme IscU
- GH14121p
- Cysteine desulfurase, mitochondrial
- Glutaredoxin-related protein 5, mitochondrial
- Adrenodoxin-like protein 1, mitochondrial
- Cytosolic Fe-S cluster assembly factor Nubp2 homolog
- LYR motif-containing protein 4 homolog
- Adrenodoxin-like protein 2, mitochondrial
- BolA-like protein DDB_G0274169
Sequence:
MATRVVATATVRAVKGRKLIPTRAALTLTPAAVLRIKTLLQDKPDMVGLKVGVRQRGCNGLSYTLDYASQKDKLDEEVVQDGVKVFIDKKAQLSLLGTEMDFVESKLSSEFVFNNPNIKGTCGCGESFSM
Protein: Uncharacterized protein (Q385Z2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQQPIGLTVQGLHGRSRQERTVQQKPIRRRWSSPPSPSPSLAPSTPPTAAASVINKNNQTNTAVVCLPSSPSTVSQLDPSVPSSSALAALEGPLPAEVREIIHNSCTGEDAELAERQARRLLSTSRRVHVYRAELQSAIEEVKDVEQLLKRHQVIQTALRTELNDLNGRIEQLLKERRLCEIQLQQQGDEEQRRAAKLQEANMRVDILRSTIDKITNETLAGHVLLQKLVPNLHVNNYLT
Protein: Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha) (P08240)
Organism: Homo sapiens (Human)
Function: Component of the signal recognition particle (SRP) complex receptor (SR). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SRP subunit SRP54. SRP receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P32916}; Peripheral membrane protein {ECO:0000250|UniProtKB:P32916}; Cytoplasmic side {ECO:0000250|UniProtKB:P32916}. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain. {ECO:0000250|UniProtKB:P32916}.
Interaction partners:
- Signal recognition particle receptor subunit beta
- Signal recognition particle subunit SRP54
- Large ribosomal subunit protein uL23
- Signal recognition particle subunit SRP72
- Signal recognition particle subunit SRP68
- Signal recognition particle 9 kDa protein
- Large ribosomal subunit protein uL18
- Signal recognition particle 19 kDa protein
- Large ribosomal subunit protein uL14
- Protein transport protein Sec61 subunit alpha isoform 1
Sequence:
MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA
Protein: Auxin-responsive protein IAA4 (Auxin-induced protein AUX2-11) (Indoleacetic acid-induced protein 4) (P33077)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
Subcellular location: Nucleus.
Interaction partners:
- Protein TRANSPORT INHIBITOR RESPONSE 1
- Auxin-responsive protein IAA2
- Auxin response factor 5
- Auxin response factor 7
- Auxin-responsive protein IAA1
- Auxin response factor 8
- Auxin transporter protein 1
- Auxin response factor 9
- AGAMOUS-like 83
- Auxin response factor 3
Sequence:
MEKVDVYDELVNLKATELRLGLPGTEETVSCGKSNKRVLPEATEKEIESTGKTETASPPKAQIVGWPPVRSYRKNNVQTKKSESEGQGNYVKVSMDGAPYLRKIDLTMYKQYPELMKSLENMFKFSVGEYFEREGYKGSDFVPTYEDKDGDWMLVGDVPWEMFVSSCKRLRIMKGSEVKGLGCGGL
Protein: Homeodomain-like protein (F4JV48)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKREMKAPTTPLESLQGDLKGKQGRTSGPARRSTKGQWTPEEDEVLCKAVERFQGKNWKKIAECFKDRTDVQCLHRWQKVLNPELVKGPWSKEEDNTIIDLVEKYGPKKWSTISQHLPGRIGKQCRERWHNHLNPGINKNAWTQEEELTLIRAHQIYGNKWAELMKFLPGRSDNSIKNHWNSSVKKKLDSYYASGLLDQCQSSPLIALQNKSIASSSSWMHSNGDEGSSRPGVDAEESECSQASTVFSQSTNDLQDEVQRGNEEYYMPEFHSGTEQQISNAASHAEPYYPSFKDVKIVVPEISCETECSKKFQNLNCSHELRTTTATEDQLPGVSNDAKQDRGLELLTHNMDNGGKNQALQQDFQSSVRLSDQPFLSNSDTDPEAQTLITDEECCRVLFPDNMKDSSTSSGEQGRNMVDPQNGKGSLCSQAAETHAHETGKVPALPWHPSSSEGLAGHNCVPLLDSDLKDSLLPRNDSNAPIQGCRLFGATELECKTDTNDGFIDTYGHVTSHGNDDNGGFPEQQGLSYIPKDSLKLVPLNSFSSPSRVNKIYFPIDDKPAEKDKGALCYEPPRFPSADIPFFSCDLVPSNSDLRQEYSPFGIRQLMISSMNCTTPLRLWDSPCHDRSPDVMLNDTAKSFSGAPSILKKRHRDLLSPVLDRRKDKKLKRAATSSLANDFSRLDVMLDEGDDCMTSRPSESPEDKNICASPSIARDNRNCASARLYQEMIPIDEEPKETLESGGVTSMQNENGCNDGGASAKNDQETSGSFFELRLCSPGMTRARPDNKVNASAKDLSNQHKISLGDFPTEEMSSEPLCTVDSIPLSAIDKTNTAETSFDIENFNIFDGTPFRKLLDTPSPWKSPLLFGSFLQSPKLPPEITFEDIGCFMSPGERSYDAIGLMKHLSEHSATAYADALEVLGNDTPESILKKRQLNKSIQGKENQHQPHDQLGNRSQVECRALDFSDCGTPGKAKVPSASPGGYSSPSSYLLKSCR
Protein: V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 55 kDa subunit) (Vacuolar proton pump subunit B) (P31409)
Organism: Drosophila melanogaster (Fruit fly)
Function: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Essential for the proper assembly and activity of V-ATPase (By similarity).
Interaction partners:
- V-type proton ATPase subunit H
- V-type proton ATPase subunit C
- V-type proton ATPase subunit G
- V-type proton ATPase catalytic subunit A isoform 2
- V-type proton ATPase subunit d 1
- V-type proton ATPase subunit E
- V-type proton ATPase subunit D 1
- V-type proton ATPase catalytic subunit A isoform 1
- V-type proton ATPase 16 kDa proteolipid subunit c
- V-type proton ATPase subunit F 1
Sequence:
MNAQQAQREHVLAVSRDFISQPRLTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKNTLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKSVLDDHTDNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGKDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLLRIFPKEMLKRIPASILAEFYPRDSRH
Protein: Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8) (P48029)
Organism: Homo sapiens (Human)
Function: Creatine:sodium symporter which mediates the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:22644605}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:12433955}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Guanidinoacetate N-methyltransferase
- Glycine amidinotransferase, mitochondrial
- Creatine kinase U-type, mitochondrial
- Creatine kinase B-type
- Hyaluronan and proteoglycan link protein 1
Sequence:
MAKKSAENGIYSVSGDEKKGPLIAPGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
Protein: SD06626p (Q8T9D1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLAQEISPTEIGKHANIIRAAQEELANMDVLVCGRCLRAYNFVEEFQAHKEDACEKENANLKESLDPKPTIWAFTLWKATQLHSRKDASGNSWALYQHWVKLDDSVREPWIVAGKTIQSFGKIAHGQLQDMPVRITKTVVNPNNNNTSNSNNNNTSVSPTRKSPTGKLPTLANQLKDTENERPKSKPSTPTPSSVPSAGAVKPNNRIAIRIDSKTDQRTEEPVEKIVAKRFNPRRKTHEYLVKWVDRSHHENTWEVMANLERVPYFLQMFEKQLARQKLTREKGLDALKRMQSSGTNAKSDTASPHSPLPASSQVSPSSRPSRTSKTKAMDAFKQWVNETVAGDGSSSPSSANEDESSTEQEWPPSSGAIKRKLNNTDSSLEGSGLNDSMDLEDLEEDLPSHTVKRLKNGGSSVQLNKPRIQSTEKQQTKINGNSTVVSPLTEQKMGEIIYTEDSTSSGMFRKPEMPNTINLKKEKPECPVRYLSRSEVGSSTRGVFRVENSEAPAPVSPAPVPQKVIAAPPAAGIAKRLPMARPAHSGANSPITVGQRQHALRTPGHGPVTAALHRRPGVGGASHVRQNLQQAPGRAHPGGRVLARAGVGTPQHRQQVQTPQGAKAVTPEQKILQLSKSGDLKVTRKVVTREELLAQRSAQARQRQALSQQQSSQQQKATPARQRIVSKSTIQPTPLQMELEEEIHQHQAQLCPITGKLIGQEETQLQMEQEQQQEQQREQLEAAAQALLGSDQQVLTNEDGSALLVRGEDGTVYQVAGKNAEGQTILVTQGPDGEQQFAYVAAAEGEDQDVLSLDHAVAEAVQAGEQVESHGVGAATADGEQILVSMTEEELAQHQVLQQAEASAAGTGTPPTAQIHITTSDSDGTESQIPAEVVQADLPSPGGTRRVVLLLQDGTFMMTEMHEDQFKTLNIPT
Protein: Probable L-type lectin-domain containing receptor kinase I.2 (LecRK-I.2) (EC 2.7.11.1) (Q7FK82)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in resistance response to the pathogenic fungus Alternaria brassicicola.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9LSR8}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAQRFYLLLLLLIFLVNLICFSSQQDLSFVFNGFNQDQAGDELLLDGFARIQSPERVLQLTDGTTQQKGHAFFNRPFDFGSASSQSLSFFTQFVCALVPKPGFYGGHGIAFVLSSAHNLKKAYASSYLGLFNRSTNGSPSSHVLAVELDTVQSAETDDMDNNHVGIDENRIQSVVSASASYYSDREGKNISLILLSGDPIQVWVDYEDTLLNVTLAPLRNQKPSKPLLSRTINLTAIFPDRKAFVGFSAATGSSISNQYILGWSFSRSRRLLKSLDISELSTVPLFTEQKRKRSPLLIVLLVILTLVVIGGLGGYYLYRRKKYAEVREPWEKEYGPLRYSYESLYKATKGFNKDGRLGKGGFGEVYKGSLPLVGDIAVKRLSHNAEQGMKQFVAEVVTMGSLQHKNLVPLLGYCRRKGELLLVSKYMEGGSVDQYLFNGDKPPLSWSQRLAILRDIASALCYLHTGASQVVLHRDIKASNVMFDDHGANLSATAAVGTIGYMALELISTGTSTKTDVYAFGAFMLEVTCGRRPFDPEMPVEKRHLVKWVCECWRKHSLVDAIDTRLRDKFTLGEVEMVLKLGLLCTSIIPESRPNMEKVMQYINRDQALPDFSPDTPGIGVSTPMVMGIPGLAITSTSVTSSASVPLVSPPSTNNSMFISHTILNGDGR
Protein: Serine/arginine (SR)-type shuttling mRNA binding protein (Q9P3U1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Pre-mRNA-splicing factor srp2
- Small ribosomal subunit protein bS18m
- Uncharacterized RNA-binding protein C106.12c
- SAC3 family protein 2
Sequence:
MPKPIEWNEFDSGMGSKLDVSSSLNSSSSNMDRDRSESPKRHVNGSNSLKRGLHFDGEHTERDPHLGNGQKYTQQERRVYVGNLSYQVRWFELKEFMGQVGNVLNCEILNLPNGLSKGCAIIEYSTAEEARTAIKTLSNQKFMGRLVYIREDREQNARFGSSSVSPSASSNGKDSEPDRQLFVGNLPYNVRWQDLKDLFRQAGSVIRADIQMNQEGRSRGIGIVVMSSMKEAMHAIQMLHNTDFMGRTLEVRLDRFAHHKSKPYSTHGNGYTFPAEMQMTTSSTYLPMLGANTQVEDLVYHAYPHGPCSDCIYVGNLPWATSDRNLLDLFTDIGSVIRARIAYEPTGRSKGFGVVQFENENDAASSIEKLNGYRYGGRPLQLSYAHYATPLPAVPTVLSGLPSVAYTPPVMHIPTTNSPLTPQSFTNSFLGYLPISMPVANMPAIAPISVALPENNIEHSLEPS
Protein: Rhomboid protease GlpG (EC 3.4.21.105) (Intramembrane serine protease) (P09391)
Organism: Escherichia coli (strain K12)
Function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:16216077}; Multi-pass membrane protein {ECO:0000269|PubMed:16216077}.
Interaction partners:
- Thiosulfate sulfurtransferase GlpE
- Sec-independent protein translocase protein TatA
- Lactose permease
- ATP-dependent zinc metalloprotease FtsH
Sequence:
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
Protein: Protein PATRONUS 1 (Protein COPPER MODIFIED RESISTANCE 1) (Q9LJG6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the maintenance of centromeric cohesion during interkinesis, until meiosis II. Required for regular configuration and segregation of sister chromatids in meiosis II. Also required for centromere cohesion during meiosis I. Involved in spindle organization at the end of telophase I and in meiosis II. Required to prevent precocious release of pericentromeric cohesins during meiosis, but not for cohesion establishment and monopolar orientation of kinetochores at meiosis I. Involved also in somatic development. Regulates mitotic cell division and ploidy stability in somatic cell types. May be involved in the organization of microtubules dynamics. Involved in abiotic stresses and mono- or divalent ions tolerance and may play a role in maintaining meristematic activity under saline conditions. PANS1 and GIG1 are part of a network linking centromere cohesion and cell cycle progression through control of APC/C activity. Regulates the number of dividing cells in root meristem and is necessary for the anaphase onset control through an APC/C-mediated pathway. Involved in maintaining correct chromosome arm cohesion under stress conditions.
Subcellular location: Nucleus {ECO:0000269|PubMed:24134393, ECO:0000269|PubMed:26272661}. Cytoplasm {ECO:0000269|PubMed:24134393}. Note=Excluded from the nucleolus. {ECO:0000269|PubMed:26272661}.
Interaction partners:
- Cell division cycle 20.1, cofactor of APC complex
- SHUGOSHIN 2
- Cell division cycle protein 27 homolog B
- SHUGOSHIN 1
- Shugoshin
- Separase
- Protein GIGAS CELL1
- Separase
- Protein PHYTOCHROME KINASE SUBSTRATE 1
- Cell division cycle protein 27 homolog A
Sequence:
MANMNALQQMIFPDENAPIHRKKSVTAASVKSKGTVLGQKKPGGARKALNDITNKSGIHAKAAASSKNKQIASAAVKEIDIAGERFLHDHSKCIKEQQNLWDDHYSADLMLLHHGSSIKEKHLNWDIEKMDAKDDLTYEEPEEMASPKFSDWLKNSTPWRSPIRHGSMMPSTPLAWRFDSCEFTLKEDSDDLF
Protein: Beta-lactoglobulin (Beta-LG) (allergen Bos d 5) (P02754)
Organism: Bos taurus (Bovine)
Function: Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
Subcellular location: Secreted.
Interaction partners:
- Alpha-lactalbumin
- Kappa-casein
- Albumin
- Lactotransferrin
- Beta-casein
- Alpha-S2-casein
- Alpha-S1-casein
- Lactoperoxidase
- Myoglobin
- Serpin domain-containing protein
Sequence:
MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI
Protein: Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Natrium iodide transporter) (Sodium-iodide symporter) (Na(+)/I(-) symporter) (Solute carrier family 5 member 5) (Q92911)
Organism: Homo sapiens (Human)
Function: Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland. Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18372236, ECO:0000269|PubMed:18708479, ECO:0000269|PubMed:20797386, ECO:0000269|PubMed:31310151}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q63008}. Cytoplasm {ECO:0000269|PubMed:18372236, ECO:0000269|PubMed:31310151}.
Interaction partners:
- Thyroglobulin
- Thyrotropin receptor
- Thyroid peroxidase
- Pendrin
- Iodotyrosine deiodinase 1
- Paired box protein Pax-8
- Dual oxidase maturation factor 2
- Forkhead box protein E1
- Homeobox protein Nkx-2.1
- Dual oxidase 2
Sequence:
MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL
Protein: Transcription factor MYB15 (Myb-related protein 15) (AtMYB15) (Myb-related protein Y19) (AtY19) (Q9LTC4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor involved in cold-regulation of CBF genes and in the development of freezing tolerance. May be part of a complex network of transcription factors controlling the expression of CBF genes and other genes in response to cold stress. Binds to the MYB recognition sequences in the promoters of CBF1, CBF2 and CBF3 genes. Involved in drought and salt tolerance. May enhance expression levels of genes involved in abscisic acid (ABA) biosynthesis and signaling, as well as those encoding stress-protective proteins.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:17015446}.
Interaction partners:
- Transcription factor ICE1
- Zinc finger protein ZAT12
- Zinc finger protein ZAT10
- E3 ubiquitin-protein ligase HOS1
- Dehydration-responsive element-binding protein 1B
- Calmodulin-binding transcription activator 3
- E3 SUMO-protein ligase SIZ1
- Dehydration-responsive element-binding protein 1C
- Dehydration-responsive element-binding protein 1A
- Probable WRKY transcription factor 33
Sequence:
MGRAPCCEKMGLKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLLRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIISLHQILGNRWSAIAAKLPGRTDNEIKNVWHTHLKKRLEDYQPAKPKTSNKKKGTKPKSESVITSSNSTRSESELADSSNPSGESLFSTSPSTSEVSSMTLISHDGYSNEINMDNKPGDISTIDQECVSFETFGADIDESFWKETLYSQDEHNYVSNDLEVAGLVEIQQEFQNLGSANNEMIFDSEMDFWFDVLARTGGEQDLLAGL
Protein: Coiled coil domain containing 88A (A0A8I5ZW24)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKTESQRVNKKVNNDASLRIHNLSILVKQIKFYYQDTLQQLIMMSLPNILVIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDTEPLLKSMASHLRRLIDERDEHSETIIELSEERDGVHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELCRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTMDSAEGSTSKILKVEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSGKLSKIEFEKRQMKKELELYKEKGERAEELENELNRLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEISVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLQDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSLPISGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKVEQEKMLLESKNHEMVAAEYKKLCGDNDRLNHTYSQLLKETEILQTDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQDSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAAFRSKQLVNNKDTTSFEDVSPQGISDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAANIQSRPQSHSSGDFSLLHDHETWSSSGSSPVQYLKRQTRSSPMLQHKMSETVDSQAHHKMNAGSPGSEVVTLQQFLEESNKLTSIQLKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCTLARSVSGKAPGDFYDRRTAKPEFLRTGPQKTEDAYSISSAGKPTPSTQGKIKLVKETSVLRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLSKDSRLPVSVEPAPPPAGGSSTAASNVNKVQESRNSKSRSREQQSS
Protein: SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1) (Q8N5H7)
Organism: Homo sapiens (Human)
Function: Acts as an adapter protein that mediates cell signaling pathways involved in cellular functions such as cell adhesion and migration, tissue organization, and the regulation of the immune response. Plays a role in integrin-mediated cell adhesion through BCAR1-CRK-RAPGEF1 signaling and activation of the small GTPase RAP1. Promotes cell migration and invasion through the extracellular matrix. Required for marginal zone B-cell development and thymus-independent type 2 immune responses (By similarity). Mediates migration and adhesion of B cells in the splenic marginal zone via promoting hyperphosphorylation of NEDD9/CASL (By similarity). Plays a role in CXCL13-induced chemotaxis of B-cells (By similarity). Plays a role in the migration of olfactory sensory neurons (OSNs) into the forebrain and the innervation of the olfactory bulb by the OSN axons during development (By similarity). Required for the efficient tyrosine phosphorylation of BCAR1 in OSN axons (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12432078, ECO:0000269|PubMed:17174122}. Cell membrane {ECO:0000269|PubMed:12432078}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QZS8}. Cell projection, axon {ECO:0000250|UniProtKB:Q9QZS8}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:Q9QZS8}. Note=Associated with the membrane when EGF-stimulated (By similarity). Expressed at the cortical actin ring in B cells (By similarity). {ECO:0000250|UniProtKB:Q9QZS8}.; SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:17174122}; Peripheral membrane protein {ECO:0000269|PubMed:17174122}.
Interaction partners:
- Serine protease 57
- Breast cancer anti-estrogen resistance protein 1
- Eukaryotic translation initiation factor 4 gamma 1
- SH2 domain-containing protein 3A
- Cytospin-B
- Interferon regulatory factor 3
- Ras GTPase-activating protein-binding protein 1
- Zinc finger CCCH domain-containing protein 7B
- Ubiquitin-like protein ISG15
- Myomesin-2
Sequence:
MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLEPDTFEATQDDMVTVPKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAARQAQEAGPKPNLVPGGVPDPPGLEAAKEVMVKATGPLEDTPAMEPNPSAVEVDPIRKPEVPTGDVEEERPPRDVHSERAAGEPEAGSDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL
Protein: Tachykinin-related peptide 2 (TKRP-2) (P86588)
Organism: Pentatoma rufipes (Forest bug) (Cimex rufipes)
Subcellular location: Secreted {ECO:0000269|PubMed:19084564, ECO:0000305}.
Interaction partners:
Sequence:
APAAGFFGMR
Protein: Peptidyl-prolyl cis-trans isomerase C (PPIase C) (EC 5.2.1.8) (Par10) (Parvulin) (Rotamase C) (P0A9L5)
Organism: Escherichia coli (strain K12)
Function: PPIases accelerate the folding of proteins (Probable). It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates.
Subcellular location: Cytoplasm.
Interaction partners:
- Chaperone SurA
- Periplasmic chaperone PpiD
- FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase
Sequence:
MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN