wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquitin fusion degradation protein, putative (Q38AI5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- UBX domain-containing protein
- MPN domain-containing protein
- Guanine nucleotide-binding protein subunit beta-like protein
- Ubiquitin thioesterase OTU
- Ubiquitin fusion degradation protein 2, putative
- UBX domain-containing protein
- Intraflagellar transport protein 56 homolog
- Polyubiquitin, putative
- Katanin p60 ATPase-containing subunit A-like 2
- DNA polymerase eta
Sequence:
MYPGKESPEIFRGSLRAFPSVFASTDAKINSGSRVILPPTCLQKLSTMRVAYPLQFKLRNGKRGVTCYAGVLEFSAEEGHIVMPAWMFTAMGLCEGSTVAIETCTLPPGGLIKLRPQESNFLQLSNPKNVLEMRLSDYPVLTKGTSIVLDYLDRDFVIDVISITDDTGKSVDAISTVRADTQATELKVEFERPLDMPPSPTESERQMPQGGNIIGADDAVEFAPFVLQPPTIGNQPQPARTKQPKEEAKAAFVPFMGVGRRIDGKSTVEEKSDTGGHRVAKTQEEMAQEAREMRLKAFGRFNAAKN
Protein: Fatty acid-CoA racemase (O53867)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MTTGGPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPGGLTMPSEDRDLLHRGKRIVDLDVKTQPQAMLELAAKADVLLDCFRPGTCERLGIGPDDCASVNPRLIFARITGWGQDGPLASTAGHDINYLSQTGALAAFGYADRPPMPPLNLVADFGGGSMLVLLGIVVALYERERSGVGQVVDAAMVDGVSVLAQMMWTMKGIGSLRDQRESFLLDGGAPFYRCYETSDGKYMAVGAIEPQFFAALLSGLGLSAADVPTQLDVAGYPQMYDIFAERFASRTRDEWTRVFAGTDACVTPVLAWSEAANNDHLKARSTVITAHGVQQAAPAPRFSRTPAGPVRPPPAAATPIDEINW
Protein: Short integuments 2, mitochondrial (DAR GTPase 1) (Q8L607)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: GTPase that may function in mitochondrial ribosome assembly (Probable). Involved in a variety of growth processes during vegetative development and promotes growth and cell division in the developing integuments.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16849600}.
Interaction partners:
- Protein Iojap-related
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein uL24c
- Large ribosomal subunit protein uL14my
- At4g38020 family protein)
- Pseudouridine synthase family protein
- Ribosome biogenesis protein BOP1 homolog
- Pescadillo homolog
- AT5G58370 protein
Sequence:
MVMMLKKTVKKGLIGGMSFAKDAGKINWFPGHMAAATRAIRNRLKLSDLVIEVRDARIPLSSANEDLQSQMSAKRRIIALNKKDLANPNVLNKWTRHFESSKQDCIAINAHSRSSVMKLLDLVELKLKEVIAREPTLLVMVVGVPNVGKSALINSIHQIAAARFPVQERLKRATVGPLPGVTQDIAGFKIAHRPSIYVLDSPGVLVPSIPDIETGLKLALSGSVKDSVVGEERIAQYFLAILNIRGTPLHWKYLVEGINEGPHADCIDKPSYNLKDLRHQRTKQPDSSALHYVGDMISEVQRSLYITLSEFDGDTEDENDLECLIEQQFEVLQKALKIPHKASEARLMVSKKFLTLFRTGRLGPFILDDVPETETDHPNSKRVVVL
Protein: Lon protease homolog, mitochondrial (EC 3.4.21.53) (Q7KUT2)
Organism: Drosophila melanogaster (Fruit fly)
Function: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner. Regulates mitochondrial DNA (mtDNA) copy number and transcription by stabilizing the mitochondrial TFAM:mtDNA ratio via selective degradation of TFAM.
Subcellular location: Mitochondrion matrix {ECO:0000255|HAMAP-Rule:MF_03120, ECO:0000269|PubMed:20930118}.
Interaction partners:
- ATP-dependent Clp protease proteolytic subunit
- GrpE protein homolog, mitochondrial
- Caseinolytic protease chaperone subunit, isoform C
- AFG3 like matrix AAA peptidase subunit 2, isoform A
- ATP-dependent zinc metalloprotease YME1L
- Paraplegin, isoform A
- Heat shock protein 75 kDa, mitochondrial
- LD23779p
- Heat shock protein 83
- Heat shock protein 83
Sequence:
MLARAIRVRPMMRGIASSSVWNRNRPIQSSLMQYCRDRSLRLQRLHGANLMVQRFYSRKRDDSNGDIIMGPDLMSDQDTHLPATVAVPDVWPHVPLLAMRKNPLFPRFMKIVEVSNPIIMDLLRRKVKLNQPYVGVFLKKTDGEEELITNLNDVYNLGTFAQIQELQDLGDKLRMVVVAHRRIRITGQVVEDVPPPKPVKMTTLHYPLFNIKLQIPAEDQSTDQADAAPIKSRSDPARKPRGRIPRSRTGKSRESAAAEELIQNQTLEPPLKSGKVESSSLPKPPTEEKIVEPETGAKENVNQSAPSAQPVLIVEVENVKQPIYKQTEEVKALTQEIIKTLRDIITMNPLYRESLQQMLHQNQRVVDNPIYLCDLGASLSAGEPAELQKILEETDIPERLQLALTLLKKELELSRLQQKIGREVEEKVKQQHRKYILQEQLKVIKKELGIEKDDKDAIGEKYREKLKDKVVPEAIMTVIDEELTKLNFLESHSSEFNVTRNYLDWLTSLPWGVISTENLCLEKATETLNDDHYGMEDIKKRILEFIAVSSLKGSTQGKILCFHGPPGVGKTSIAKSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKLIQCLKKTKIENPLVLIDEVDKIGKGYQGDPSSALLELLDPEQNANFLDHYLDVPVDLSRVLFICTANVIDTIPEPLRDRMELIEMSGYVAEEKIAIARQYLMPQAMKDCGLTDKHINISEDALNMLIRSYCRESGVRNLQKHIEKVIRKVAFRVVKKEGEHFPVNADNLTTFLGKQIFSSDRMYATTPVGVVMGLAWTAMGGSSLYIETSRRHIRQGAKTDPNTVAGSLHITGNLGDVMKESAQIALTVARNFLYSLEPNNLFLEQEHIHLHVPEGATPKDGPSAGITIITALVSLATGKPVRQDIAMTGEVSLKGKVLPVGGIKEKTIAARRSGVNCLILPVDNKKDFEELPTYITDGLEVHFATTYEDVYKIAFTDVTETTTNNVEEQEPLQKLSSAAAAKSETWPYS
Protein: Thioredoxin-like protein CDSP32, chloroplastic (Chloroplastic drought-induced stress protein of 32 KDa) (AtCDSP32) (Q9SGS4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable thiol-disulfide oxidoreductase involved in resistance to oxidative stress. May participate in the reduction of alkyl hydroperoxides derived from oxidative stress by acting as a physiological electron donor to the BAS1 peroxiredoxin. May regenerate methionine sulfoxide reductase B1 (MSRB1) activity through sulfenic acid reduction.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:12084836, ECO:0000269|PubMed:19259774}.
Interaction partners:
- NADPH-dependent thioredoxin reductase 3
- 2-Cys peroxiredoxin BAS1, chloroplastic
- 2-Cys peroxiredoxin BAS1-like, chloroplastic
- Thioredoxin M4, chloroplastic
- Peroxiredoxin Q, chloroplastic
- Peroxiredoxin-2E, chloroplastic
- Thioredoxin F1, chloroplastic
- Thioredoxin-like protein HCF164, chloroplastic
- Thioredoxin-like 2-1, chloroplastic
- Peptide methionine sulfoxide reductase B1, chloroplastic
Sequence:
MATVANFLAKPISTVVPRPSSAVASTSSFVFFNHKTNPLFRRKNLPKRLFSAVKIKAGAASPGKVGTPPANDEKVQKIHSGEEFDVALKNAKSKLVVAEFATSKSDQSNKIYPFMVELSRTCNDVVFLLVMGDESDKTRELCRREKIEKVPHFSFYKSMEKIHEEEGIEPDQLMGDVLYYGDNHSAVVQLHGRPDVEKLIDENRTGGKLIVLDVGLKHCGPCVKVYPTVLKLSRSMSETVVFARMNGDENDSCMEFLKDMNVIEVPTFLFIRDGEIRGRYVGSGKGELIGEILRYSGVRVTY
Protein: Vacuolar protein sorting/targeting protein 10 (Carboxypeptidase Y receptor) (CPY receptor) (Sortilin vps10) (Vacuolar carboxypeptidase sorting receptor vps10) (O42930)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:16622069}; Single-pass type I membrane protein {ECO:0000269|PubMed:16622069}. Prevacuolar compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Cycles between the Golgi apparatus and the prevacuolar compartment. {ECO:0000250}.
Interaction partners:
- Carboxypeptidase Y
- Vacuolar protein sorting-associated protein 35
- Vacuolar protein sorting-associated protein 26
- Vacuolar protein sorting-associated protein 29
- Sorting nexin-3
- V-type proton ATPase subunit a
- Vacuolar protein sorting-associated protein vps5
- Putative mannose 6-phosphate receptor-like protein C530.09c
- Uncharacterized carboxypeptidase C24C9.08
- Vacuolar protein sorting-associated protein 17
Sequence:
MFFLTKILPLRGRIFPMFGCLLLIVSLITGCIASPAAEVAETVFDSKPVDFMTFKDSTNTLFLNAEFGDVYLSQDNGQSWRNGVISGQVCPIKKLIKHSFENSRVFALTECDTVYYSYDNGENWDYFTIDHPISITQLPFHFHAKNPDYVIFNNQYCSSSGTWVGKICKPDLYYTKDGFQSDPEPMPVGSSYCIFADSSEKMVVSSEEQIICISLNPNSAARPPFSHHIVYSDDWFQSIVPVQLHNFLGSDGAYGILSTGSFLVAALIDAATRKLFVYVSQDGYYWEEALKFHKGFEFDAFTILPSTEYSFFIDSLDSHPNNPTGILYSLDSESNTFVIRQMNTNRYVDGYTDFMLIDYLDGLQFVNVVENVDEIEVDPQVDKVLSSRITFDGGKTWSTVASPESSCNSMKQCSLHLFLDPHVSHASIASSKFAPGILLASGSVGDRLLSENQMDLFVSEDGGRNWTLSRDGMHLFAMSGFGSIFFASEYLDVINEVYYSLDHGQSWVTVTLDKTIVPIKLFASEDPYAEIFYLLAMTDDGEQSNYSLFSFNFGKFLPKECQFSNSESNKNDFEKWYTRYANGSPICSEMGKKEFFWRKKATSVCSVPKSITDLHGSFDACECTDEDYECNTQFISNDQGECKLLDFIGSLLCASEDLDTFQKIPYRLVPGNKCTPNKRDSHREPQTFNCDSFNEPGTEITSFLYDFDEKIVDVVYLEGTVPEENTFLIGISVNSHVYFSEDEGKTWDKFSKEEFSSVLPHAYNKNSVYMVTSKNIVYFTTNRGKNFYKFKAPSPPNQNGKSLFSFHPSRPAWLLYAGSENCEKNPFADDCRDVVFVSLDFGDTWSRLPSNLEYCSWAKAEKLVVDDTLIFCIRQNTNDPFKKELISSIDFFEYEQDEILNDVVGFMIEDEYVIVAVQDEEGTSLSLDVSINGLNFASCSFPAYLNVHPKQAYTILDSQTHSLFIHVTTNTHLGSEWGDILKSNSNGTYFMTSLANVNRDSVGYVDFERLEGIQGIALANIVSNTKELTDGGTKKLQTLITFNDGLDWSYLNLVGGEKIVPKCGKNCYLHLHGYTERNQFSDPTSTNAAVGLIIGVGSFSPFLIPYEESQTFISRDAGVTWYRIFDSPHLWAFLDSGSIIIAVESISPTNVIKYSADEGRTWQEYQFSEKSKVVVDVSTKPSGVGHQVLLLTTDDENAPISSVLIDFDALYRRTCVFDEENSEESDFVRWVPTDISGKPLCLRGRISSFYRKSIHKKCRVGSSLLVKEEVLSKCECTRADFECDYNYRRLKDGTCVLVSGLQPPDTREEQCSVDDAFEWRQPTGYKRTPLTECEGGVPLDAGTLHPCPGKEDDYYKAHPKPGGWSIFLTIIFSILLAAVAGCILYYYSRRFLKGAIRLGSDSATENPLESGISYTRGAFSSIPIFFSALYQSVRSLFIRSTPTNGEFENAAFLQNYEIDDDDEESV
Protein: Peptidyl-prolyl cis-trans isomerase pin1 (PPIase pin1) (EC 5.2.1.8) (O74448)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in the G1/S stage transition of mitosis where it is involved in the dephosphorylation of cdc25 and wee1.
Subcellular location: Nucleus {ECO:0000269|PubMed:11707530}.
Interaction partners:
- SH3 domain-containing protein C23A1.17
- DNA-directed RNA polymerase II subunit rpb1
- Protein scd2/ral3
- Large ribosomal subunit protein uL14m
- RNA polymerase II subunit A C-terminal domain phosphatase ssu72
- Peptidyl-prolyl cis-trans isomerase
- Phosphatidylinositol 4-phosphate 5-kinase its3
- SAM50-like protein SPAC17C9.06
Sequence:
MSNTGLPKPWIVKISRSRNRPYFFNTETHESLWEPPAATDMAALKKFIANELQESVTPTEASNSPKIRASHLLVKHRESRRPSSWKEEHITRSKEEARKLAEHYEQLLKSGSVSMHDLAMKESDCSSARRGGELGEFGRDEMQKPFEDAAFALKPGEISGVVETSSGFHIIQRHA
Protein: Uncharacterized protein C22H10.11c (Q10304)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Enoyl-[acyl-carrier-protein] reductase, mitochondrial
- Target of rapamycin complex 1 subunit toc1
Sequence:
MALTNGRIEEYDIQNGYQNTEEIKKLPAELNFPVDFDKMPTFIFQEERQKLDLPLSDSEENQFHDFSDSKLSLGFEIGRSKEKFVDEKPFYSNKEPLKINSWKKSSSHPKSKEVSNGLLKVSTPPTEFVKRENAGIRRRSSNQGSFALEAPKILKRDAMFKESWKNKCFISPQKDNQGFSKSKHLSTYEGETENGFSTSTEEEEEEEEDIVSASWVDNLDMDMASFNSHRERFLTEHVNMDERSDDDFLLGLISSDSSVDDHDNEQDDVDLIGWECFFDDSSDELNTLSHQADDEGDTTDEETPELQNNKLLNLSTPKKSFGQTPRIKTELSESPNSQRTLLSAVPTPLELSAELAYKEDLTSLASRANISDNSTGLTPTLAKATLAQPVSTVVSVASFELDPRLNITQPKPPVMGTWAKEPNHLIGIIDGKHSHSLHHDKFDACTKGENTANNGYGPQTLNETSEEPSLDDILDTSLLQPSTQTDLQEENSVSFAQEDNSLSRWEKIPIGTFRKNQYIKSMARRDELIRDEWFTLAIKTREKRRHKINATGMTTTNSVPLRPKSRKARRALKKKARKMTFRQMHSDFQSALEDEHNDGSYLDNDYETVGLGLGPELSPLFEILESSGY
Protein: RRM domain-containing protein (Q3U8W9)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMSPPMRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK
Protein: Alpha-glucosides permease MPH3 (Maltose transport protein 3) (P0CE00)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High-affinity uptake of maltose and maltotriose. Also transports alpha-methylglucoside, glucose and turanose but not melezitose or trehalose.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein.
Interaction partners:
Sequence:
MKNLSFLINRRKENTSDSNVYPGKAKSHEPSWIEMDDQTKKDGLDIVHVEFSPDTRAPSDSNKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSLLVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEIVGLQLTGPSVDLVGNRYTLIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQWILPVPLALGIFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGSILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLGCSSTHGSKMGSGSLLMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLGVSARKFKSTKVDPFVVKTPPKDVSHNDPKGDIEASIAEE
Protein: SNW domain-containing protein 1 (G3V4X8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU367140}.
Interaction partners:
Sequence:
MPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE
Protein: Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48) (P28828)
Organism: Mus musculus (Mouse)
Function: Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation. Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P28827}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P28827}. Note=Localizes in regions of cell-cell contact. {ECO:0000250|UniProtKB:P28827}.
Interaction partners:
- Catenin beta-1
- Catenin delta-1
- Neuropilin-1
Sequence:
MRTLGTCLVTLAGLLLTAAGETFSGGCLFDEPYSTCGYSQADEDDFNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAAPGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAISTFWPNFYQVIFEVVTSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMICTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYGYQVGGQEQVREEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYEFETPLNQTDNTVTVMLKPAQSRGAPVSVYQIVVEEERPRRTKKTTEILKCYPVPIHFQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATKGAVTPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMGTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDETHTMASDTSSLAQPHTYKKREAADVPYQTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQMLEGDNNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIDTELLAEYVIRTFAVEKRGIHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRIYNASRPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG
Protein: Mas-related G-protein coupled receptor member X1 (Mas-related G-protein coupled receptor member C11) (Sensory neuron-specific G-protein coupled receptor 1) (Q8CIP3)
Organism: Mus musculus (Mouse)
Function: Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception.
Subcellular location: Cell membrane; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MDPTISSHDTESTPLNETGHPNCTPILTLSFLVLITTLVGLAGNTIVLWLLGFRMRRKAISVYILNLALADSFFLCCHFIDSLLRIIDFYGLYAHKLSKDILGNAAIIPYISGLSILSAISTERCLCVLWPIWYHCHRPRNMSAIICALIWVLSFLMGILDWFSGFLGETHHHLWKNVDFIITAFLIFLFMLLSGSSLALLLRILCGPRRKPLSRLYVTIALTVMVYLICGLPLGLYLFLLYWFGVHLHYPFCHIYQVTAVLSCVNSSANPIIYFLVGSFRQHRKHRSLKRVLKRALEDTPEEDEYTDSHLHKTTEISESRY
Protein: Rab1 protein (O02591)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MITAASPGGDCDYIFKIIVIGDSGVGKSSLTVRLSEDVFYKDYASTIAIDFRMHQMTYMDKRVRLQIWDTAGQERFQSVATAFYRGANGVMLCFDLTHRPSFLHLEHWMERVRQQSLPGIPCLLVGCKSDEARTSRQVSKEEAMAWAKQHGMSYIDTSAKEKENVQSAFQKIAQEIFEDMKERTGKGLSPSGGAGGAGNGVRLAGNEGQKGSKRGGCC
Protein: Galactose oxidase (Q383Z5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEWVPCTEQTGSVGCREGHCATSLQEKSTGEEWVLVVGGYCEGERDGAVMAARADGLPMLRWVRLDKPNMTWFECDGASLTHVTGDTAYFFGGLNEHMNHSNQLLCLSLHQGQQGDLSLDVVKVETTGDVPLPRARHSAGSAGRYFVVFGGETEDAEQNNDGYILDTDTMVWTRIPTGHQVPNPRLLAGPLVFYSPHGCILYGGAHFVNGDIRSMSDVWNLHIPLGGTWFNVSYGDGAPACRFPRSNGHAGGVLGRVGGETVVLFVGGKDAAEGCDRVKQVQPPKSAEDKFHLRLVDPVLAGGEGPHWRYTPAAVDTRRGVLLLGGQCRHPQEVAAFLLKQTGVTLQR
Protein: Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Hepatoma-associated antigen) (HAb18G) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147) (P35613)
Organism: Homo sapiens (Human)
Function: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.
Subcellular location: Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000269|PubMed:17081065}.; SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:25957687}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453}. Photoreceptor inner segment {ECO:0000250|UniProtKB:P18572}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P18572}.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane {ECO:0000269|PubMed:11992541, ECO:0000269|PubMed:15688292, ECO:0000269|PubMed:15946952, ECO:0000269|PubMed:17127621, ECO:0000269|PubMed:21536654, ECO:0000269|PubMed:25825981, ECO:0000269|PubMed:26195724, ECO:0000269|PubMed:28409866, ECO:0000269|PubMed:29739904}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453}. Endosome {ECO:0000269|PubMed:29739904}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:15688292}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453}. Basolateral cell membrane {ECO:0000269|PubMed:17267690}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453}.; SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane {ECO:0000269|PubMed:21536654}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453}.; SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane {ECO:0000269|PubMed:21536654}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453}.
Interaction partners:
- Monocarboxylate transporter 1
- Peptidyl-prolyl cis-trans isomerase A
- Monocarboxylate transporter 4
- Monocarboxylate transporter 3
- Peptidyl-prolyl cis-trans isomerase B
- Caveolin-1
- CD44 antigen
- Interstitial collagenase
- Monocarboxylate transporter 5
- RING-type E3 ubiquitin-protein ligase PPIL2
Sequence:
MAAALFVLLGFALLGTHGASGAAGFVQAPLSQQRWVGGSVELHCEAVGSPVPEIQWWFEGQGPNDTCSQLWDGARLDRVHIHATYHQHAASTISIDTLVEEDTGTYECRASNDPDRNHLTRAPRVKWVRAQAVVLVLEPGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS
Protein: Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C) (Allergen Gal d IV) (allergen Gal d 4) (P00698)
Organism: Gallus gallus (Chicken)
Function: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.
Subcellular location: Secreted.
Interaction partners:
- Ovotransferrin
- Src substrate protein p85
- Ovotransferrin
- Ovotransferrin
- Ovalbumin
- Uncharacterized protein.
- Uncharacterized protein.
- Ovomucoid
- Uncharacterized protein.
- Lysozyme g
Sequence:
MRSLLILVLCFLPLAALGKVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Protein: Nuclear transcription factor Y subunit C-9 (AtNF-YC-9) (Transcriptional activator HAP5C) (Q8L4B2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity). Interacts with REF6 to directly regulate SOC1 transcription in response to flowering signals from photoperiod and gibberellic acid pathways.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Nuclear transcription factor Y subunit B-3
- Nuclear transcription factor Y subunit B-2
- Nuclear transcription factor Y subunit B-1
- Nuclear transcription factor Y subunit B-10
- Nuclear transcription factor Y subunit B-8
- Nuclear transcription factor Y subunit A-2
- Nuclear transcription factor Y subunit B-6
- Nuclear transcription factor Y subunit B-4
- Nuclear transcription factor Y subunit B-7
- Nuclear transcription factor Y subunit A-4
Sequence:
MDQQDHGQSGAMNYGTNPYQTNPMSTTAATVAGGAAQPGQLAFHQIHQQQQQQQLAQQLQAFWENQFKEIEKTTDFKNHSLPLARIKKIMKADEDVRMISAEAPVVFARACEMFILELTLRSWNHTEENKRRTLQKNDIAAAVTRTDIFDFLVDIVPREDLRDEVLGSIPRGTVPEAAAAGYPYGYLPAGTAPIGNPGMVMGNPGGAYPPNPYMGQPMWQQQAPDQPDQEN
Protein: DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed] (Q9BRT9)
Organism: Homo sapiens (Human)
Function: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Subcellular location: Nucleus {ECO:0000305|PubMed:35585232}. Chromosome {ECO:0000305|PubMed:35585232}. Cytoplasm {ECO:0000250|UniProtKB:Q99LZ3}. Note=Associates with chromatin. {ECO:0000305|PubMed:35585232}.
Interaction partners:
- DNA replication licensing factor MCM6
- TIMELESS-interacting protein
- DNA replication licensing factor MCM2
- WD repeat and HMG-box DNA-binding protein 1
- Cell division control protein 45 homolog
- DNA replication complex GINS protein PSF3
- DNA replication licensing factor MCM3
- DNA replication complex GINS protein PSF2
- DNA replication licensing factor MCM7
- DNA replication complex GINS protein PSF1
Sequence:
MTEEVDFLGQDSDGGSEEVVLTPAELIERLEQAWMNEKFAPELLESKPEIVECVMEQLEHMEENLRRAKREDLKVSIHQMEMERIRYVLSSYLRCRLMKIEKFFPHVLEKEKTRPEGEPSSLSPEELAFAREFMANTESYLKNVALKHMPPNLQKVDLFRAVPKPDLDSYVFLRVRERQENILVEPDTDEQRDYVIDLEKGSQHLIRYKTIAPLVASGAVQLI