wanglab/gogpt-training-data huggingface dataset:
Protein: Guanylate cyclase 2D (EC 4.6.1.2) (Guanylate cyclase, olfactory) (ONE-GC) (Olfactory guanylyl cyclase GC-D) (GC-D) (P51839)
Organism: Rattus norvegicus (Rat)
Function: Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity).
Subcellular location: Cell projection, cilium membrane {ECO:0000269|PubMed:11580282}; Single-pass type I membrane protein {ECO:0000269|PubMed:18178149}. Note=Colocalized with NCALD at the apical region of the cilia (PubMed:11580282). Coexpresses with PDE2 (By similarity). {ECO:0000250|UniProtKB:A0A0U1RPR8, ECO:0000269|PubMed:11580282}.
Interaction partners:
- Neurocalcin-delta
- Guanylyl cyclase-activating protein 2
- Guanylyl cyclase-activating protein 1
- Retinal guanylyl cyclase 2
- Retinal guanylyl cyclase 1
- Inosine triphosphate pyrophosphatase
- Phosphodiesterase
- cGMP-dependent 3',5'-cyclic phosphodiesterase
- Phosphodiesterase
- Phosphodiesterase
Sequence:
MAGLQQGCHPEGQDWTAPHWKTCRPCQGPRGLTVRHLRTVSSISVFSVVFWGVLLWADSLSLPAWARETFTLGVLGPWDCDPIFAQALPSMATQLAVDRVNQDASLLLGSQLDFKILPTGCDTPHALATFVAHRNTVAAFIGPVNPGYCPAAALLAQGWGKSLFSWACGAPEGGGALVPTLPSMADVLLSVMRHFGWARLAIVSSHQDIWVTTAQQLATAFRAHGLPIGLITSLGPGEKGATEVCKQLHSVHGLKIVVLCMHSALLGGLEQTVLLRCARKEGLTDGRLVFLPYDTLLFALPYRNRSYLVLDDDGPLQEAYDAVLTISLDTSPESHAFTATKMRGGTAANLGPEQVSPLFGTIYDAVILLAHALNHSEAHGTGLSGAHLGNHIRALDVAGFSQRIRIDGKGRRLPQYVILDTNGEGSQLVPTHILDVSTQQVQPLGTAVHFPGGSPPARDASCWFDPNTLCIRGVQPLGSLLTLTITCVLALVGGFLAYFIRLGLQQLRLLRGPHRILLTPQELTFLQRTPSRRRPHVDSGSESRSVVDGGSPQSVIQGSTRSVPAFLEHTNVALYQGEWVWLKKFEAGTAPDLRPSSLSLLRKMREMRHENVTAFLGLFVGPEVSAMVLEHCARGSLEDLLRNEDLRLDWTFKASLLLDLIRGLRYLHHRHFPHGRLKSRNCVVDTRFVLKITDHGYAEFLESHCSFRPQPAPEELLWTAPELLRGPRRPWGPGKATFKGDVFSLGIILQEVLTRDPPYCSWGLSAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPDDRPSLDQIYTQFKSINQGKKTSVADSMLRMLEKYSQSLEGLVQERTEELELERRKTERLLSQMLPPSVAHALKMGTTVEPEYFDQVTIYFSDIVGFTTISALSEPIEVVGFLNDLYTMFDAVLDSHDVYKVETIGDAYMVASGLPRRNGNRHAAEIANMALEILSYAGNFRMRHAPDVPIRVRAGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSRNTVQALLSLDEGYKIDVRGQTELKGKGLEETYWLTGKTGFCRSLPTPLSIQPGDPWQDHINQEIRTGFAKLARVG
Protein: Uncharacterized GMC-type oxidoreductase Rv0492c (EC 1.1.-.-) (P9WMV7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized protein Rv0493c
- Uncharacterized protein
- 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
- Tetratrico peptide repeat group 5 domain-containing protein
- Cytochrome bc1 complex cytochrome c subunit
- Outer membrane protein Rv1973
- Probable conserved Mce associated membrane protein
- Sulfotransferase
- Omega-hydroxy-beta-dihydromenaquinone-9 sulfotransferase Stf3
- Uncharacterized HTH-type transcriptional regulator Rv0494
Sequence:
MSRLADRAKSYPLASFGAALLPPELGGPLPAQFVQRVDRYVTRLPATSRFAVRAGLASLAAASYLTTGRSLPRLHPDERARVLHRIAALSPEVAAAVEGLKAIVLLANGADTYAHELLARAQEHDAARPDAELTVILSADSPSVTRADAVVVGSGAGGAMVARTLARAGLDVVVLEEGRRWTVEEFRSTHPVDRYAGLYRGAGATVALGRPAVVLPMGRAVGGTTVVNSGTCFRPSLAVQRRWRDEFGLGLADPDQLGRRLDDAEQTLRVAPVPLEIMGRNGRLLLQAAKSLGWRAAPIPRNAPGCRGCCQCAIGCPSNAKFGVHLNALPQACAAGARIISWARVERILHRAGRAYGVRARRPDGTTLDVLADAVVVAAGATETPGLLRRSGLGGHPRLGHNLALHPATMLAGLFDDDVFAWRGVLQSAAVHEFHESDGVLIEATSTPPGMGSMVFPGYGAELLRWLDRAPQIATFGAMVADRGVGTVRSVRGETVVRYDIAPGEIAKLRVALQAIGRLLFAAGAVEVLTGIPGAPPMRSLPELQDVLRRANPRSLHLAAFHPTGTAAAGADEQLCPVDATGRLRGVEGVWVADASILPSCPEVNPQLSIMAMALAVADQTVAKVVGVR
Protein: Cytokine receptor family member B7 (Interleukin-10 receptor subunit alpha precursor) (A0FJI2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDWTLWICFLVCCTPGLIAGEQKKLNLTFDIWEGNVTVLWDPPNKAPVPAFYQVKLALDTGPHAKWNIVQECDMITETKCNLGNFIFKPTMKVKIELISGNNESSWLVIRRIRLDYIKLLSPDFDLFSGPNTVKVKIHRKPFLKELFPYGLSYSAILYPRGQESKAKTLSDDDDEDGEVEFTDLSYWQTYCVRVRLEITSIAVSNTSLPRCIHPPTDLSVVISIGVIGVVGVITLFMLFVCFFLRRPGKMPAVLKLAVNGWLPMNVGQTEVESVTQKGWLLNSNKIAEKTKAFDEIEELSEDEKERRESTDSGVSIGQQDSIKNRPQREEDSGCGSLTGTEDSLSSGRRSLEELPFLDGGGNSSSVEGTREDSGLGIQTQDISDKPKPMHDDLLSEIVVIGDGYRSQSPSAEAETETTIQCDEDANMVSRTNGYRSGQVTCLCSDSETCMWCKTRKHLTDCDSFSHKQTVNDNDRSSYLKKSPLETVNMFGLDDLSCHSDKTEESSLFITCPLLLKEPYKLDTLPLTLGDVELTFT
Protein: Carbamoyl phosphate synthase arginine-specific small chain (CPS-A) (EC 6.3.5.5) (Arginine-specific carbamoyl phosphate synthetase, glutamine chain) (O60060)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:200419}. Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Carbamoyl phosphate synthase arginine-specific large chain, mitochondrial
- Amidophosphoribosyltransferase
- Argininosuccinate synthase
- Glutamine synthetase
- Glutamate synthase
- Ornithine carbamoyltransferase, mitochondrial
- Protein arg11
- Multifunctional protein ura1
- Probable glutamine--fructose-6-phosphate aminotransferase
- Dihydroorotate dehydrogenase
Sequence:
MLRFLKPFPLRFGKRFYSKVPPVTNHERILPKQPSFPTAPAQNEIATLTIRNGPIFHGTSFGANRNVSGEAVFTTSPVGYVESLTDPSYKQQILIFTQPLIGNYGVPDCKKRDENGLLRHFESPHIQCAGVVVNDYATKYSHWTAVESLGEWCAREGVAAITGVDTRAIVTFLREQGSSLAKISIGEEYDANDDEAFINPEEVNLVSQVSTREPFFVSGGDGMLNIAVIDCGVKENILRSLVSRGASVTVFPFDYPIQNVASNYDGIFLTNGPGDPTHLTKTVNNLRELMNTYNGPIMGICMGHQLLALSTGAKTIKLKYGNRGHNIPALDIASGNCHITSQNHGYAVDASTLPAEWKATWTNLNDQSNEGIAHVSRPISSVQFHPEARGGPMDTFYLFDNYIKEAIKYQKSRTA
Protein: Monoterpene epsilon-lactone hydrolase (EC 3.1.1.83) (Q9EX73)
Organism: Rhodococcus erythropolis (Arthrobacter picolinophilus)
Function: Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone derivatives of dihydrocarvone (4R)-4-isopropenyl-7-methyl-2-oxo-oxepanone and (6R)-6-isopropenyl-3-methyl-2-oxo-oxepanone, and ethyl caproate.
Interaction partners:
Sequence:
MSATDTARAKELLASLVSMPDATIDDFRALYEQVCATFELPDDAQVEPVDANGADALWVSAPGVSADTVAVVVHGGGFTMGSAHGYRELGYRLSKSGNLRALVVDYRLAPESPFPAPVDDVVAAYRYARSLDGVENVFLVGDSAGGGIAMSALITLRDAGEQLPDAAVVLSPLVDLAGESPSLVDRAHLDPLPAAVLVNGMGGLYLNGLDVRHPVASPMHGDLTGLPATLVLVGTDEGLHDDSTRLVDKLKAADVEVQLEIGEGLPHIWPIFSFHPDAVAATDRIGEFLRSHVAAPR
Protein: Outer envelope pore protein 37, chloroplastic (Chloroplastic outer envelope pore protein of 37 kDa) (PsOEP37) (Q4LDF9)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: Voltage-dependent peptide-sensitive high conductance rectifying cation channel with a strong affinity for TIC32 that is imported into the chloroplast. Conductance is pH-dependent decreasing with decreasing pH values.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MDSATRNPNYSPEVDPQPLPSTNPIHSRPIFSFPKRPALRITTEFDSESTVFFHKISCKFLDSLAKLKFAFHNNSKGEIAEPQISFVSKYLSLHYDLEDHSALVKSSVDVGPKLKLIGTHDVKAQQGEVTMVANLDDPGYALQLSTPLPSIALPKATFKFPQGEISLQEINDHDEDEQVKNSLSVSGTLKGQLLKGLCTAQYKDQEFKLRYRYKDDEMSFLPILSLPSNALSFAFKRRFGPSDKLSYWYNCDSNYWSAVYKHTYGEDFKFKAGYDSEVRLGWASLWVGDEGGKAKTAPMKMKVQFMLQVPQDDIKSSVLMFRVKKRWDI
Protein: Tubulin alpha chain (A9PL14)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Uncharacterized protein LOC107899987
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta chain
Sequence:
MREIISVHIGQAGIQVGNSCWELYCLEHEIHPDGTMPSDTSVGVAHDAFNTFFSETGSGKHVPRAVFVDLEPTVIDEVRTGPYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRVRKLADNCTGLQGFMVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVLLDNEAIYDICRRSLDIERPTYTNLNRLISQIISSLTTSLRFDGAINVDITEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVPEITNAVFEPSSMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTVQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNNTAVAEVFARIDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAEGGDDEEEGEEY
Protein: Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase) (Q9D1I5)
Organism: Mus musculus (Mouse)
Function: Methylmalonyl-CoA epimerase involved in propionyl-CoA metabolism.
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Methylmalonyl-CoA mutase, mitochondrial
- Propionyl-CoA carboxylase beta chain, mitochondrial
- Propionyl-CoA carboxylase alpha chain, mitochondrial
- Malonate--CoA ligase ACSF3, mitochondrial
- Ethylmalonyl-CoA decarboxylase
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Cobalamin trafficking protein CblD
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Methylmalonic aciduria type A homolog, mitochondrial
- Corrinoid adenosyltransferase MMAB
Sequence:
MRRVVKAAALAAGATGLFSRVQTSVAIGRSFSTPQSQFQESSPVWKLGRLNHVAVAVPDLEKASSFYRDVLGAQVSEVVPLPEHGVSVVFVNLGNTKMELLHPLGSDSPITGFLQKNKAGGMHHVCIEVDNISAAVMDLKKKKIRSLSDEAKIGAHGKPVIFLHPKDCGGVLVELEQA
Protein: Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (Q95QP3)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU365061}. Chromosome, telomere {ECO:0000256|RuleBase:RU365061}.
Interaction partners:
Sequence:
MSTFLASSENISNIRDTVVLLEINKLSQSILSSRNIFELRKLKPTRKMVEIEHCFVSKNDTFVACSKLISMFHLEKYIGSTNCANILEWITKMLNNGGYHKMKPFVYKEAPFTRAFRASKVMKNVDPNVKRNIQTSIVNNLKSGVHWWALMALRQVMIPIVIKEERVLLWRDGYLNILTKEIKDFKQRYIVQKAPHFIRPNVATFKLSISRQKLRPLFKRKAIDKKTETMQWKRLNSMLSWCLERSGVYRHTIRDSCKKVSDFLKKNSQNSKIIGYTADVSKCFSTVNHDVLISIIDRLFSQEHDIYTVCGKGRNHGGFHKLIFCSAGTELNAHEALRRKMELKGVFNFEVCYREMSSSTTLYSVIRTTLSTYYYKRGPTSWRITKGVPQGHPISSNLAHMYLNNFEQKYWSNEKEDSRIVFCRYEDDFIFITTENSLFEKMMKPLSTGNNTHFLTANPKKFKKSERCGASQVLQWCGVKLDFQSGNCFIRRRCKDGVARQFLIKLQ
Protein: DUF218 domain-containing protein (Q57X82)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRTRFRNKRRTWPLIAIVFIVLMFSLLRAKLLLQADTPGGAAEREANPKYLSTDTLIIVPGHGVLNAPNASEWKNESEWCLEPHQLRAGVVLPLCFASHIRRGLEILRDQINTSILIFSGGQTCGIAGPRSEALGYYIVAKESKLFGIFEPEYVAKDIMNGRIFTEEFARDSYENLLFSIARFYEVTGHFPGSVVVVGWKHKAERFTMYHREAIRFPADKFTYVGLDFADAEPFVEDLQPYQVAKPYTDENALSSVSKDMYLCDAGRRTRSKRNPYFRVPPYLVSCPPLRQLLQHCGPELIDTRRVPWK
Protein: Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11) (Q8R361)
Organism: Mus musculus (Mouse)
Function: Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
Subcellular location: Cytoplasm {ECO:0000250}. Recycling endosome membrane {ECO:0000269|PubMed:19335615}; Peripheral membrane protein {ECO:0000269|PubMed:19335615}. Early endosome membrane {ECO:0000269|PubMed:19335615}; Peripheral membrane protein {ECO:0000269|PubMed:19335615}. Golgi apparatus membrane {ECO:0000269|PubMed:19335615}; Peripheral membrane protein {ECO:0000269|PubMed:19335615}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:19335615}; Peripheral membrane protein {ECO:0000269|PubMed:19335615}. Mitochondrion membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Ras-related protein Rab-11A
- Ras-related protein Rab-11B
- Rab11 family-interacting protein 2
- Rab11 family-interacting protein 1
- EH domain-containing protein 1
- Rab11 family-interacting protein 3
- Unconventional myosin-Vb
- Rab11 family-interacting protein 4
- Spermatogenesis-defective protein 39 homolog
- Kinesin-like protein KIF3A
Sequence:
MALVRDPEPAAGSSRWLPTHVQVTVLRASGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTQGCPEWCEECSFELPPGALDGLLRAQEADAGPAPWASGPNAACELVLTTMHRSLIGVDKFLGRATVALDEVFRAGRAQHTQWYRLHSKPGKKEKERGEIQVTIQFTRNNLSASMFDLSMKDKPRSPFSKLKDRVKGKKKYDLESASAILPSSALEDPELGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSTSGSLVYQGPGAELLTRSPSHSSWLSTEGGRDSIQSPKLLTHKRTYSDEASQLRAAPPRALLELQGHLDGASRSSLCVNGSHVYNEEPQPPLRHRSSISGPFPPSSSLHSVPPRSSEEGSRSSDDSWGRGSHGTSSSEAVPGQEELSKQAKGASCSGEEEGARLPEGKPVQVATPMVASSEAVAAEKDRKPRMGLFHHHHHQGLSRSEQGRRGSVGEKGSPSLGASPHHSSTGEEKAKSSWFGLRESKEPTQKPSPHPVKPLTAAPVEASPDRKQPRTSLSTALSSGLERLKTVTSGGIQSVLPASQLGSSVDTKRPKDSAVLDQSAKYYHLTHDELIGLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQISPGPPK
Protein: Fascin (Q08C47)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR005682}.
Interaction partners:
Sequence:
MTANGTSDMLKIQFGLINCGNKYLTAETFGFKINASATSMKKKQIWTLEQDGDDSNMFFLKSHLGRYIAADKDGNVTGDSETPGEDCRFIITAHDDGRWSLQSEPHKRYLGGTEDRITCFAQTISIAEKWSVHIAMHPQVNIFSVTRKRYAHLSSEQNEIAIDRDVPWGVDSLITLVFQDQRYHLQTSDNRFLKNDGSLSQTADKTTGYTLEFRSGKVAFRDCTGKYLAPSGPSGTMKSGKSMKVGKDELFVLEQSLPQVVLTAGNDRNVSTRQGMDLSANQDEEGDQETFQMEISKDTKKCAFRTCTGKYWTLTANGGLQCTASTKSANCYFDIEWRGKKITLRATNGKYVAAKKNGQLAATIDSAGETEEFLMKLINRPLIVLRGEHGFIGCRRVTGTLDSNRSSYDVFGLDFNDGAYSLRDCTGKYWMVGSESNVLSSSDTPVDFFLEFCNYNKVAIKTTEGKYLKGDHAGVLKANADDLDSSTMWEY
Protein: High-affinity zinc uptake system protein ZnuA (Q9HT75)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
Interaction partners:
- Zinc import ATP-binding protein ZnuC
- High-affinity zinc uptake system membrane protein ZnuB
- Probable permease of ABC transporter
- Probable ATP-binding component of ABC transporter
- High-affinity zinc uptake system protein ZnuA
- Transcriptional regulator np20
- Type IV pilus biogenesis factor PilY1
- Stringent starvation protein B
- Type IV major pilin protein PilA
- PA-I galactophilic lectin
Sequence:
MTLRPFALLSTCFALFLLASPARAEVSVLTSIKPLQLVAAAIQDGVGQPDVLLPPGASPHQYALRPSDVRRLREVQLFYWIGPDLENFLPKVLAGRQGTSVAVQDLPGMHLRKFVNFEEEEHAGHDEHDHDHRPGMLDAHLWLLPANARTIAARMAEDLAQVDPANAGRYRANLKAFDERLGGLDGKLRERLGKLAGKPFFVFHEAFDYFEEAYGLRHTGVFAVSAEVQPGARHVAAMRAQLKAAGPACIFSEPPLRPRLADTLSEGLPVRLAELDDLGVNVSVDANGYENLLNNLAGEFAGCLEKL
Protein: Nuclear receptor coactivator 4 N-terminal domain-containing protein (Q9CXF3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MNTSLEQSGCYSNRETLLRCSDARRELELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFNCLIHQLEYTQNKDPANQVSVCLERLGSLALKPEDSTVLLFEADTSALRQTITTFGSLKTIQIPEHLMAHASSSSIGPFLEKRGYIQVPEQKSASSGTAVSLSEWLLVSKPAIGLQAPYVPSTNPQDWLIPKQTSENSQTSARACSFFSDAWGNLKGLENWLLNSHQQEIAGKPSSSKCNSHCSTSSFSPEAEKAEDVELLDQDELDLSDWLVTPQEPCELEKPVDGSWETSEKFKLLFQVFREPYNVSDWLVKPDSCTNCQGNQPRGVEIENLGNLKCLNDHL
Protein: ER oxidoreductin (A0A1D8PER8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004367}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004367}; Lumenal side {ECO:0000256|ARBA:ARBA00004367}.
Interaction partners:
- protein disulfide-isomerase
- Protein disulfide isomerase
- Protein disulfide isomerase
- Thioredoxin domain-containing protein
- Endoplasmic reticulum chaperone BIP
- Autophagy-related protein 22
- Hsp70 family chaperone
Sequence:
MKIFRLFSLLIVQFIINTTVAVSPVSAVLPKSSFSPFDSPEFCSQIITPTCNTTFTYIDELNKDIRPYLSELVKTSYFRYFKVNLDKQCRFWNAQHFCASENCAVEILEDFNWSQVTNESLKPSGLGKISLPDKSSIDNSIETEEVQTCEDLDYSEIDDDHHCVYVNLVNNPERFTGYGGNQSFDVWKAIYSENCFPNTNPMSVTNDADNGGEQCIEKNLFYRVVSGMHASIAVHLSREYLNSETGEFYPNLKVFMERVGMHNDRLSNIYFNYALVSQAIVKLSEILPLREFIQSGYDDITPAQKQHLLANNDVESVEVYDRLLLDDIIPSLEANVVFNTSNLFDNSNLRDEFRSRFRNISAIMDCVGCDRCRMWGKIQTIGYGTALKILFEDDNYDNHNLKFRRIEIVALINTFDRLSKSIESINMFKEMYLQHLKDVAEGLTQPGVYDKIQNNKPGNGFAFPFVSPLPQKKPDQTNTPKNQQQKQPQETDKKRLTLEEIAHTKPEDRTFIEDFRLSFDEVWQALRFVLTSYQRFPAVLSRFTLVQLNEWWNKLLGKPTVYEYESAIDVDAQQYSQVIG
Protein: Protein NAM8 (Nuclear accommodation of mitochondria protein 8) (U1 snRNP component NAM8) (Q00539)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the U1 small nuclear ribonucleoprotein complex (U1 snRNP) involved in the initiation of meiotic recombination. Involved in the formation of DSBs at recombination hot-spots through meiosis-specific splicing of REC107 pre-mRNA. Collaborates with MER1 to promote splicing of essential meiotic mRNAs REC10, AMA1, MER3, HFM1, SPO22 and PCH2. NAM8 interacts with the pre-mRNA downstream of the 5' splice site, in a region of non-conserved sequence and is required for efficient splicing of uncapped RNA precursor.
Interaction partners:
- Branchpoint-bridging protein
- U1 small nuclear ribonucleoprotein A
- U1 small nuclear ribonucleoprotein 70 kDa homolog
- Splicing factor MUD2
- Protein HSH49
- Protein LUC7
- U1 small nuclear ribonucleoprotein component SNU71
- Small nuclear ribonucleoprotein Sm D1
- Pre-mRNA-splicing factor PRP21
- U2 snRNP component HSH155
Sequence:
MSYKQTTYYPSRGNLVRNDSSPYTNTISSETNNSSTSVLSLQGASNVSLGTTGNQLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRSAKQTALLQQAMLSNSLQVQQQQPGLQQPNYGYIPSSTCEAPVLPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLLADTSSMDLSGTGGQQVIMQGSEAVVNSTNAMLNRLEQGSNGFMFA
Protein: DUF1663 domain-containing protein (Q57XP1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Flagellar attachment zone protein 1 conserved domain-containing protein
- Flagellar attachment zone protein 1 conserved domain-containing protein
Sequence:
MRSRNTDAPSRRRGGLARAAGLLKRAATRRDSLESKTVASFTSSPPPSAPQDRVSRTSTVGMWEDVDTRSASRYYEKNPPSPIRLNSAFHRSYGGQVGQGFKAARAHPMSATTSIGRFGSILFSGDTVSVPRGRGHSKSPALSPAADIIAHIVTDDLKGSVERSRREVSTDPPCWRVQHDEDIARHELHIEEMEAYSALIQKMMTHRVLQVKAYQQRLDAEEKMWLALQNVHAVIEKEEERRNLIVSKESVDRRNLTRKVDGGECSDEEEPAVEINPGEWISYAYPLQTEKLRIQESAQRQRMYLEHAIAIHKLQTRMRLALKMLNAARIKKEEIDEKGHPTEKYPVRKSNTNESLLLWNSWDSDLDEAMDQEIYELINILWKNDKVSHSTPTTLNETQDMASTQSPTKRHIKADDEEPEKIKTTEREGIINTHEQRKNYKQRIICREEHERDKIMENEVNAMFNILRNTNKTQKEEIYEDANKEKIQKKIEEKKKDEYSHEIKENNHQGISDKDNENSTKNNSAETNNKSNETRIRSTSTKVDCAFDLHDQFTDDMLAISMDNATTTETQDREGLQGDECRERFALCASAIEGEEDASRKDIVCAYDDCAFDLHDQFTDDMLAISMDNVTTTETQDREGLQGDECRERFALCASAIEGEEDASRKDIVCAYDDCAFDLHDQFTDDMLAISMDNVTATETQDREGLQGDECRERFALCASAIEGEEDASRKDIVCAYDDCAFDLHDQFTDDMLAISMDNVTTTETQDREGLQGDECRERFALCASAIEGEEDASRKDIVCAYDDCAFDLHDQFTDDMLAISMDNVTTTETQDREGLQGDECRERFALCASAIEGEEDASRKDIVCAYDDCAFDLHDQFTDDMLAISMDNATTTETQDPKGLYFFAETLITFSAGESTESTFGDKAGDVPYSGFDSERRGLALGAFNTYGAGTSLQNDGLRAGEGVDSLRPFSAGETAESTFGDKAGDVLYSGFDSDRRGLALGAFNTYGAGTSLQNDGLRAGEGVDASGSFSCSLMDVEEDERILLLQEEDRRFKRLLKRFVSRPVNDLEKRRGTPNMRVDVASFTCGCVLERWVIRNR
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 15.6) (Np15.6) (p15.6) (O09111)
Organism: Mus musculus (Mouse)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:38575788}; Single-pass membrane protein {ECO:0000255}. Note=The interaction with BCAP31 mediates mitochondria localization. {ECO:0000250|UniProtKB:Q9NX14}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 6, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 3
- NADH dehydrogenase 1 beta subcomplex subunit 6
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- NADH-ubiquinone oxidoreductase chain 4
- NADH dehydrogenase 1 alpha subcomplex subunit 11
- NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial
Sequence:
MAARLLSLYGRCLSAAGAMRGLPAARVRWESSRAVIAPSGVEKKRQREPTMQWQEDPEPEDENVYAKNPDFHGYDSDPVVDVWNMRAVFFFGFSIVLVFGTTFVAYVPDYRMQEWARREAERLVKYREVNGLPIMESNYFDPSKIQLPEDD
Protein: EG:63B12.5 protein (Peroxin 5, isoform B) (Q7KW08)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
Interaction partners:
Sequence:
MSFRPLVEGDCGGVNPLMQLGGQFTRDVAHKDEGYVQRHFERAARPEDQLINEFLGQVTAPPQSFQMDTLLQEMRDINIHGNPQQQMHSQQAEQWGQDFARGLAPALPNKMIHMQAQQQDLQHAQEFFDEPLISSQNFRSLPPLRQPLMPIAAGQQQDPFFDSAMETIITDHLPQAPQGESLDDWISDYQRSTEQKEQTAANFNEKFWERLQDEWQKLADENEHPWLSEYNDNMDAYKEYEFAEGNPMSDVENPFEKGKEYLSKGDIPSAVLCFEVAAKKQPERAEVWQLLGTSQTENEMDPQAIAALKRAYDLQPDNQQVLMALAACYTNEGLQNNAVRMLCNWLTVHPKYQHLVAAHPELQAEGTSLASSLIGPSKLRDLQQIYLEAVRQHPSEVDAEVQDALGVLYNLSGEFDKAVDCYQSALQVDPQNAKTWNRLGASLANGSRSVEAVEAYQQALQLQPGFIRVRYNVGVCCMNLKAYKEAVEHLLTALTMQAHTNAARELPNAAMAATFRGQNQMSESIWSTLKMVISLMGRSDLQSYVSDRNLAALNEAFKD
Protein: U6 snRNA-associated Sm-like protein LSm1 (D3ZWB1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU365047}. Cytoplasm, P-body {ECO:0000256|RuleBase:RU365047}.
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm4
- U6 snRNA-associated Sm-like protein LSm7
- Protein PAT1 homolog 1
- U6 snRNA-associated Sm-like protein LSm3
- 5'-3' exoribonuclease 1
- U6 snRNA-associated Sm-like protein LSm2
- U6 snRNA-associated Sm-like protein LSm5
- U6 snRNA-associated Sm-like protein LSm6
- Probable ATP-dependent RNA helicase DDX6
- U6 snRNA-associated Sm-like protein LSm8
Sequence:
MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGRKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQSRLEAEKLKVQALKDRGLSIPRADTLDEY
Protein: Sucrose synthase 1 (OsSUS1) (EC 2.4.1.13) (Sucrose synthase 2) (RSs2) (Sucrose-UDP glucosyltransferase 1) (P31924)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
Interaction partners:
- Probable sucrose-phosphatase 3
- Probable sucrose-phosphatase 1
- Sucrose-phosphatase 2
- Starch synthase, chloroplastic/amyloplastic
- Granule-bound starch synthase 1, chloroplastic/amyloplastic
- UTP--glucose-1-phosphate uridylyltransferase
- UTP--glucose-1-phosphate uridylyltransferase
- Os01g0196600 protein.
- Glucose-1-phosphate adenylyltransferase large subunit 4, chloroplastic/amyloplastic
- Glucose-1-phosphate adenylyltransferase small subunit 2, chloroplastic/amyloplastic/cytosolic
Sequence:
MGEAAGDRVLSRLHSVRERIGDSLSAHPNELVAVFTRLVNLGKGMLQAHQIIAEYNNAISEADREKLKDGAFEDVLRSAQEGIVISPWVALAIRPRPGVWEYVRVNVSELAVELLTVPEYLQFKEQLVEEGTNNNFVLELDFEPFNASFPRPSLSKSIGNGVQFLNRHLSSKLFHDKESMYPLLNFLRAHNYKGMTMMLNDRIRSLSALQGALRKAEEHLSGLSADTPYSEFHHRFQELGLEKGWGDCAKRSQETIHLLLDLLEAPDPSTLEKFLGTIPMVFNVVIMSPHGYFAQANVLGYPDTGGQVVYILDQVRAMENEMLLRIKQQGLNITPRILIVTRLLPDATGTTCGQRLEKVLGTEHTHILRVPFRTENGIVRKWISRFEVWPYLETFTDDVAHEIAGELQANPDLIIGNYSDGNLVACLLAHKMGVTHCTIAHALEKTKYPNSDLYWKKFEDHYHFSCQFTTDLIAMNHADFIITSTFQEIAGNKDTVGQYESHMAFTMPGLYRVVHGIDVFDPKFNIVSPGADMSIYFPYSESRKRLTSLHPEIEELLYSEVDNNEHKFMLKDRNKPIIFSMARLDRVKNLTGLVELYGRNPRLQELVNLVVVCGDHGNPSKDKEEQAEFKKMFDLIEQYNLNGHIRWISAQMNRVRNGELYRYICDTKGAFVQPAFYEAFGLTVVESMTCGLPTFATAYGGPAEIIVNGVSGFHIDPYQGDKASALLVEFFEKCQEDPSHWTKISQGGLQRIEEKYTWKLYSERLMTLTGVYGFWKYVSNLERRETRRYLEMLYALKYRTMASTVPLAVEGEPSNK