wanglab/gogpt-training-data huggingface dataset:
Protein: Structural maintenance of chromosomes protein (Q38DK9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005719}.
Interaction partners:
- Structural maintenance of chromosomes protein
- SCD domain-containing protein
- Sister chromatid cohesion protein
- Double-strand-break repair protein rad21 homolog, putative
- EF-hand domain-containing protein
- Nuclear condensin complex subunit 3 C-terminal domain-containing protein
- Sister chromatid cohesion protein
- Uncharacterized protein
- DNA polymerase eta
- Condensin complex subunit 2
Sequence:
MSSRIERVELFNFKSYSGHVTIGPLKDFTCIVGPNGSGKSNLMDALCFVLSSNSTATLRGGSPTDFIHRGAQQRECFVTVVLRHSRADSIGSSIVSVKNGGSDNMPETSFTRIVDSAGRIKHKVNGKPVGEEDFVSALRKVNIGPRVNNFLVFQNEVQSVSKKKAQELTEFLERVSGSIEFKEEYDRLKKTGELAKIELAKAAAARREAGSALTVARDQKKETEKYSETMKRISEERCNEALVELLSIENRIRKQKRQLALQSAELEKLMKTFTSAQDAEEMKRTYAEKNKSYLEEINQNRKDISDLRNLRSSLDNAMVRLEHLKRSHDEKRRKMESVLANEENRSRQKERIEEEIRKQKALLAAFDGRCKEEDKNYTSLSDALNKEQLKEYGRLRVASRCQTSTLRQQVDRVRGEQQSMSEGKKQCLVSIENITMQRDNLLVEVQRSDALITELQQRQEELRERAKELSKNSAMKQAEITHAERRNREAEVELEKINAQLGELHFIEENDKREAKVTEALEELKVLHGVRGRLVDLCTIPNNKYRHAVTVALGKNLEAVVVDTSETAHACVRYLKERRLPPLTFLPLNSVNGSAVDDRLRTLGGTCKPVVDVICFDASIEAAVRYALGQTLVCDTMGEGRRIAYGQSSGERFKVVTCDGTVLRRNGVVQGGLAATRSRAQKWDKKKYEDLRAAQKRLIEGTNGWFESELSQLRHELQGMQEGLRFTEQRQKAVKEEIERARSKVEGLRQKVKQQEAELHAVEERRASYEEGLKRCEKELEAGLAAIKRAEQELFGDFQKRVNIPNLLEYEQNDLRRANEREEQRQTLLMLIGKLELSLNSNHGHVTFGSKDLRAECEEIESLIKKCEAELTATKKVVKEKEVKVNETGARVVQLRGDLMKLKERRDQQDRRQEDERQKLRQVRQVVRILEAGCETFRLQRMNVVRRCQMENVPILLKPVDAVGKKRLRPSDADDLSFSEPFALIEADTPDPSQQSQQQDRRPALKAAAEDGRVMIDFSVLSENLRLVAANDAQLSQYKQRTASLLETLQRTVESLGPNLRAATRVVDCEAKLALCNAQFDAVHKRVREIDSNLMKVKHLRTKRFFETYNKIAVHVGNVYKGLTKSDSDGLVHGIACLNLENEDEPYLGGTLYNATPPMKRCTEIERLSGGERTMAALALLFAVHATSPTPFFVLDEVDAALDAANVQRLAKYTRENCNTTQFIVISLMDQLYHMADMLVGVLKDKERGSSSILTMDLSSYPLVVGGGNKHINGY
Protein: 2S seed storage albumin protein (16 kDa buckwheat protein) (BWp16) (2S albumin) (2S seed storage protein) (Buckwheat 16 kDa major allergen) (allergen Fag e 2.0101) (Q2PS07)
Organism: Fagopyrum esculentum (Common buckwheat) (Polygonum fagopyrum)
Function: Seed storage protein.
Interaction partners:
Sequence:
MKLFIILATATLLIAATQATYPRDEGFDLGETQMSSKCMRQVKMNEPHLKKCNRYIAMDILDDKYAEALSRVEGEGCKSEESCMRGCCVAMKEMDDECVCEWMKMMVENQKGRIGERLIKEGVRDLKELPSKCGLSELECGSRGNRYFV
Protein: Rac-like GTP-binding protein ARAC6 (GTPase protein ROP5) (Q9SBJ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in cell polarity control during the actin-dependent tip growth of pollen tubes.
Subcellular location: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with the membrane when activated.
Interaction partners:
- Immunoglobulin E-set superfamily protein
- At1g12070
- Guanine nucleotide exchange factor SPIKE 1
- Rho GDP-dissociation inhibitor 1
- KOW domain-containing protein
- CRIB domain-containing protein RIC3
- Kinesin-like protein KIN-14E
- CRIB domain-containing protein RIC4
- Coatomer subunit zeta-1
- Dol-P-Glc:Glc
Sequence:
MSASRFIKCVTVGDGAVGKTCLLISYTSNTFPTDYVPTVFDNFSANVVVNGATVNLGLWDTAGQEDYNRLRPLSYRGADVFILAFSLISKASYENVSKKWIPELKHYAPGVPIVLVGTKLDLRDDKQFFIDHPGAVPITTVQGEELKKLIGAPAYIECSSKSQENVKGVFDAAIRVVLQPPKQKKKKNKAQKACSIL
Protein: D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH (EC 3.4.-.-) (DD-alanine-endopeptidase) (DD-carboxypeptidase) (Penicillin-binding protein AmpH) (P0AD70)
Organism: Escherichia coli (strain K12)
Function: Hydrolyzes the cross-linked dimers tetrapentapeptide (D45) and tetratetrapeptide (D44). Removes the terminal D-alanine from muropeptides and disaccharide pentapeptide M5 with a C-terminal D-Ala-D-Ala dipeptide. Associated with recycling and remodeling of peptidoglycan (PG). Also displays a low beta-lactamase activity.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:22001512}.
Interaction partners:
- D-alanyl-D-alanine carboxypeptidase DacB
- Penicillin-binding protein 1A
- D-alanyl-D-alanine carboxypeptidase DacD
- Murein DD-endopeptidase MepH
- D-alanyl-D-alanine endopeptidase
- D-alanyl-D-alanine carboxypeptidase DacA
- D-alanyl-D-alanine carboxypeptidase DacC
- Penicillin-binding protein 1B
- Penicillin-binding protein 1C
- Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase
Sequence:
MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFYGSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLDQGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPTREQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMKDTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQRSNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGFITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS
Protein: Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) (Q9MZ34)
Organism: Bos taurus (Bovine)
Function: Mediates sodium- and chloride-dependent transport of taurine. Can also mediate transport of beta-alanine, hypotaurine and gamma-aminobutyric acid (GABA) (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P31641}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWASRIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVIIGQYTSEGGITCWEKICPLFAGIGYASIVIVSLLNIYYIIILAWAMYYLFQSFQSELPWAKCNHSWNTPHCLEDTLRRNRSLWISNSTANFTSPVTEFWERKVLSLSSGIDEPGALKWDLALCLLLVWLVCFFCIWKGVKSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLHPSLLRKGFHREIFIASICCVTYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFAIAWIYGSDNFYDGIEDMIGYRPGPWMKYCWAVVTPLLCTGCFIFSLVKYVPLTYNKVYTYPTWAIGLGWCLALSSMVCVPLVMVIRLAQTEGPFLVRLKYLLTPREPNRWAVEHEGAMPYSSRMAVNNTLRKPTHIIVETMM
Protein: ATP-dependent protease La (LON) domain protein (Q682J5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g01015
- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
- Fanconi anemia group E protein FANCE protein
- Phosphorylase superfamily protein
- AT5G12460.1
- ARM repeat superfamily protein
- Pentatricopeptide repeat-containing protein At2g18520
- Fanconi anemia group F protein
- Small ribosomal subunit protein mL103
- RING-type E3 ubiquitin transferase
Sequence:
MLFSTAELNGESLNPITAIHIFPMTSTLISSNLSSSFFPTQNIHRIRIPTTSIPGSFNIRARRSKIVAKSLDLPLLPFSMSEVLVPTESKTLHLYEARYLALLEESMKRKKNMFVHFILDPISISETATEASFAARYGCLVLIENVERLDVGALVSIRGAGRVKISRFLGADPYLSGEVRPIQDRMNYESSNELTSKISQLKESIKNLNSLEIKLKAPADSPLQTRLINSLNWAEDEPPVDFDESFVPSLQERLSFSAFQPISGSTKSELSRLQQEKIKAMDMKDTIERLELSMGLIKENISSIAAKLAIQSLDIR
Protein: Probable maleylacetoacetate isomerase 1 (MAAI 1) (EC 5.2.1.2) (Glutathione S-transferase zeta 1) (EC 2.5.1.18) (Q9VHD3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid in vitro. Possesses low glutathione thioltransferase activity toward 4-hydroxynonenal (4-HNE). Has no glutathione thioltransferase activity with adrenochrome, phenethyl isothiocyanate (PEITC), 5-hydroperoxyeicosatetraenoic acid ((5S)-HpETE), prostaglandin A2 (PGA2) or 2-hydroxyethyldisulfide (HED).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Homogentisate 1,2-dioxygenase
- Fumarylacetoacetase
- Probable maleylacetoacetate isomerase 2
Sequence:
MASATQLTHRGIHLAGLYRSSWSKPLFRHLATKPILYSYWPSSCSWRVRVALAIKKIDYDIKPTSLLKTVSGHAYTDEYREVNPMQKVPSLKIDGHTLCDSVAIIHYLEETRPQPALLPQDPVKRAKIREIVELICSGIQPLQNVSVLDHIGKDQSLQWAQHWISRGFQGLEKVLSHSAGKFCVGDELSMADICLVPQVRNARRYKADLTPYPTIVRLNQELQELDVFKATHPSTQPDCPPEFAKK
Protein: Kininogen 1 (Kininogen-1 precursor) (Kng1 protein) (Q5XJ76)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MARDKILTVLAMLWLYFCGGLAQTDSSVPCDDRRVEKVVNLTLGTHNKMITEGAQLALYEILEATKAQNESGDVLLVRFSSRETDCPAGGEKTWHECDYLQQADKALRICHAKVQFTEAGEELLLHDCLEPAIIASVAPCLGCPENIDVHKEELRQPLIHSLSKANSMINHVHFFIFKDLTSATKQVVAGFRYKLQFEIEKSNCTRPEFKIVTEECHPLLEKTEVLKCNSSVDVAPWRHEVPEVHVVCEAGVSKTNSRFKRPPGWSPLRMLPQAKESSEESKESISPPKHVPLNCPTKPWKEFKPIIAPPNATEPSEPSADTALSDLDLIR
Protein: Putative F-box only protein 11 (Q9SYD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F-box/LRR-repeat/kelch-repeat protein At1g09650
- SKP1-interacting partner 15
- Protein UNUSUAL FLORAL ORGANS
- Putative F-box/FBD/LRR-repeat protein At5g44960
- F-box/kelch-repeat protein At5g42360
- F-box/kelch-repeat protein At5g48990
- Putative F-box protein At1g50870
- Putative F-box/kelch-repeat protein At2g44030
- F-box/kelch-repeat protein At5g48980
- Putative F-box protein At1g20800
Sequence:
MVSVNLPWELVEEILCRVPPQSLVKFRTVCKQWNSLFDDNKFVNDHFVQSQPQLIFRTESKIYSVAVNFKGPRIEVHELPLAIPGLKSEMPIRLHDYVDCDGLLFCTSYFNGVLIWNPWLRQTRFFPSIHRYPVTYDIGYDNKKQYKMLDYYKCEGDSSIKSIIYEIGLYSKKVKDLESDSTWSIFQSNSVSLNGTLYWAGVDVNNGIFIRSFSFSTEKPRTFCSLPFMYDDDNVLALAVFRKDRLSLLNLCNKTSEIKIWLTKNNINDREVGLEEDVVWINLMTVLIPNFPKFSFYWYNRPDLTYFLDNDDAKRLVICCYDETDQAYIYIVKGDMFKKIKIDQYEVLSDYSRPHFHTYIPSLVRPSRVKEDNKN
Protein: 24.1 kDa heat shock protein, mitochondrial (OsHsp24.1) (Q6Z7V2)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Os06g0592500 protein
Sequence:
MASIVASKRIPLFRLVEQLLAASPAQGAASALRPVAVAGGSRAYNTGAQLRRHERDESDDDSGRGYDTRRPTRDATMPAFFSDVFRDPFSAPQSLGRLLSLMDDLATPAGRAGAATLRRGWNAKESEEALHLRVDMPGLGKEHVKVWAEQNSLVIKGEGEKEAGEDEGAAPARYSGRIELAPEVYRMDQIKAEMKNGVLKVVVPKVKEEQRRDVFQVNVE
Protein: Epc1 protein (Q4KM29)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESVRVNSPVRPAARPAPSAARGGGGAADPHKMAAIFSPPPTLGRRPGRSPASPGARSRAAEARRSTLEGLPPSSATGTRVPRSSGARKAQRGHVTKPPAAILWSQFLGWALCISGEGSGLGGGGGAASREWAAPAGPSQGR
Protein: Serine/threonine-protein phosphatase 2A regulatory subunit phr2AB (Protein phosphatase 2A 55 kDa regulatory subunit) (Protein phosphatase 2A B55 regulatory subunit) (Protein phosphatase 2A PR55 regulatory subunit) (Protein phosphatase 2A regulatory B subunit) (Q54Q99)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:18673380}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18673380}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A catalytic subunit A
- Protein phosphatase 2A scaffold subunit
- Serine/threonine-protein phosphatase 2A regulatory subunit psrA
- EF-hand domain-containing protein
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
- UDP-N-acetylglucosamine transporter slc35b4
- Serine/threonine-protein phosphatase 4 catalytic subunit
- separase
- Serine/threonine-protein phosphatase 2B catalytic subunit
- Nuclear exosome regulator NRDE2
Sequence:
MTEPLDWRFSQTFGGKGNEDASDANVVPAIEFDQTGDFIAVGDKGGKVLLLKRTHDKQSSKKSKLPEYRFYSEFQSHEPEFDYLKSLEIEEKINKIKWCPKQNDAQFLLTTNDKTIKLWKVYEKKIKQVSTSATTTGPSYNGSLASNNTRSPSHTTYIYNSSGAHNMNNNMNNSNNNNNLNNFKIPKLTTRETVVTATPRKIFQNAHAYHINSISLNSDGETYISSDDLRIHLWNLNINTECFNVVDIKPTNMEDLTEVITSAEFHPTSCNIFMYSSSKGTIKLGDLRSSALCDNHAKVFEEYEDPSNKSFFSEIISSISDIKFSRDGRYILSRDFLTLKLWDINMENKPVKTIQIHDYLKPKLCDLYENDCIFDKFECTLNHDGTQMLTGSYHNYLHIYDRNSKQDVCLEASKQATKSKTKTLTTKMKLRSSKKEPKKPEDIHPDAIEYTKKTLHCAWHPKDNLIAVGAANTVYLYAATENK
Protein: Ankyrin-repeat and fibronectin type III domain containing 1 (Q8CDJ6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MPLSGPLHTAAVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDSSSEQNLKKISSTSSHIDCLPSTSPSPEMHRRKAVSESQPCSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYLSSHDIAQQALSGLSGSAPDVLQVHDMKASMGPGQDPQGPGQGPDTDHSCVEFLHSLTLTGLAPKNHAKMVAGTRPPLGFLGKRKPGKHQHYGGFSRHHRWLRMHSETQSLSLSEGVYTQHLSQACGLAEDPGEAEGPGPVVDGPRGLPLAHAASLPEERRSCLQDPRRPLQRVYVEPYSDTLAGQDPKLWTSLSPTPAGRSSLPSSTSSEMSPDPTSPVSEILSSML
Protein: Protein SLE2 (Em protein) (Protein Glycine max physiologically mature 11) (Protein GmD-19) (Soybean group-1 late embryogenesis abundant protein 2) (Soybean group-1 lea protein 2) (Sle2) (I1JLC8)
Organism: Glycine max (Soybean) (Glycine hispida)
Function: Late embryogenesis abundant (LEA) protein interacting with non-reducing sugars and phospholipids.
Interaction partners:
- Late embryongenesis abundant protein
- 18 kDa seed maturation protein
- 18 kDa seed maturation protein
- Late embryosis abundant group 4 protein PM9
- Seed maturation protein PM28
- Glycinin G2
- 51 kDa seed maturation protein
- Lea protein
- Beta-amylase
Sequence:
MASRQNNKQELDERARQGETVVPGGTGGKSLEAQQHLAEGRSKGGQTRKEQLGTEGYQEMGRKGGLSTVEKSGEERAQEEGIGIDESKFRTGNNKNQNQNEDQDK
Protein: EVI5-like protein (Ecotropic viral integration site 5-like protein) (Q96CN4)
Organism: Homo sapiens (Human)
Function: Functions as a GTPase-activating protein (GAP) with a broad specificity.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase 10
- Ras-related protein Rab-23
Sequence:
MASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKGQVTRAQEAEENYVIKRELAVVRQQCSSAAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNVAQLQEELKALKVREGQAVASTRELKLQLQELSDTWQAHLARGGRWKESPRKLVVGELQDELMSVRLREAQALAEGRELRQRVVELETQDHIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKAEVRLLKGPPPFEDPLAFDGLSLARHLDEDSLPSSDEELLGVGVGAALQDALYPLSPRDARFFRRLERPAKDSEGSSDSDADELAAPYSQGLDN
Protein: Interleukin-1 beta (IL-1 beta) (P21621)
Organism: Ovis aries (Sheep)
Function: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P01584}. Secreted {ECO:0000250|UniProtKB:P01584}. Lysosome {ECO:0000250|UniProtKB:P01584}. Secreted, extracellular exosome {ECO:0000250|UniProtKB:P10749}. Note=The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10. {ECO:0000250|UniProtKB:P01584}.
Interaction partners:
- Interleukin-1 alpha
- Interleukin-1 receptor type 1
- Interleukin-1 receptor type 2
- Apoptosis-associated speck-like protein containing a CARD
- Interferon gamma
- Interleukin-10
- Granulocyte-macrophage colony-stimulating factor
- Interleukin-4
- Interleukin-8
- T-cell surface glycoprotein CD4
Sequence:
MATVPEPINEVMAYYSDENELLFEVDGPKQMKSCTQHLDLGSMGDGNIQLQISHQLYNKSFRQVVSVIVAMEKLRSRAYEHVFRDDDLRSILSFIFEEEPVIFETSSDELLCDAAVQSVKCKLQDREQKSLVLDSPCVLKALHLPSQEMSREVVFCMSFVQGEERDNKIPVALGIRDKNLYLSCVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKNTVEFESVLYPNWYISTSQIEEKPVFLGRFRGGQDITDFRMETLSP
Protein: Malate dehydrogenase, mitochondrial (EC 1.1.1.37) (Q9Y7R8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable citrate synthase, mitochondrial
- Fumarate hydratase, mitochondrial
- Aspartate aminotransferase, mitochondrial
- Pyruvate carboxylase
- Aspartate aminotransferase, cytoplasmic
- NAD-dependent malic enzyme
- Probable ATP-citrate synthase subunit 1
- Probable ATP-citrate synthase subunit 2
- NAD-dependent malic enzyme
- Probable isocitrate dehydrogenase, mitochondrial
Sequence:
MFAKVAFKNFTPLKSIAPRSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGAPGVAADIGHINTTSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETCPEAKYLVVTNPVNSTVPIFKKALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNGKAELLHIPVVGGHSGATIVPLLSQGGVELTGEKRDALIHRIQFGGDEVVKAKAGAGSATLSMAYAGARMASSVLRALAGESGVEECTFVESPLYKDQGIDFFASRVTLGKDGVDTIHPVGKINDYEESLLKVALGELKKSITKGEQFVA
Protein: Ubiquitin carboxyl-terminal hydrolase 17-like protein B (USP17-B) (EC 3.4.19.12) (Deubiquitinating enzyme 1A) (E9Q9U0)
Organism: Mus musculus (Mouse)
Function: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 17-like protein E
Sequence:
MVVALSFPEADPAMSPPSAPELHQDEAQVVEELAANGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAHVTQSLLHTHSGDVMKPSQNLTSAFHKRKQEDAHEFLMFTLETMHESCLQVHRQSEPTSEDSSPIHDIFGGWWRSQIKCHHCQGTSYSYDPFLDIPLDISSVQSVKQALQDTEKAEELCGENSYYCGRCRQKKPASKTLKLYSAPKVLMLVLKRFSGSMGKKLDRKVSYPEFLDLKPYLSQPTGGPLPYALYAVLVHEGATCHSGHYFCCVKAGHGKWYKMDDTKVTSCDVTSVLNENAYVLFYVQQNDLKKGSINMPEGRIHEVLDAKYQLKKSGEKKHNKSPCTEDAGEPCENREKRSSKETSLGEGKVLQEQDHQKAGQKQENTKLTPQEQNHEKGGQNLRNTEGELDRLSGAIVVYQPICTAN
Protein: Endothelial cell-specific chemotaxis regulator (Apoptosis regulator through modulating IAP expression) (ARIA) (Endothelial cell-specific molecule 2) (Q19T08)
Organism: Homo sapiens (Human)
Function: Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.
Subcellular location: Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Interaction partners:
Sequence:
MGTAGAMQLCWVILGFLLFRGHNSQPTMTQTSSSQGGLGGLSLTTEPVSSNPGYIPSSEANRPSHLSSTGTPGAGVPSSGRDGGTSRDTFQTVPPNSTTMSLSMREDATILPSPTSETVLTVAAFGVISFIVILVVVVIILVGVVSLRFKCRKSKESEDPQKPGSSGLSESCSTANGEKDSITLISMKNINMNNGKQSLSAEKVL
Protein: Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (P61764)
Organism: Homo sapiens (Human)
Function: Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:20887364}. Membrane; Peripheral membrane protein.
Interaction partners:
- Syntaxin-1A
- Synaptosomal-associated protein 25
- Syntaxin-1B
- Syntaxin-2
- Amyloid-beta A4 precursor protein-binding family A member 1
- Syntaxin-3
- Vesicle-associated membrane protein 2
- Protein unc-13 homolog B
- Synaptotagmin-like protein 4
- Amyloid-beta A4 precursor protein-binding family A member 2
Sequence:
MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS
Protein: EG:152A3.5 protein (Fbgn0003116;pn protein) (GH15456p) (Prune (EC 3.6.1.11)) (O18399)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Guanosine-3',5'-bis
- Protein PDF
- PDF receptor
Sequence:
MCFLRFLAQARGTLGRHLAEASPVAWAAAPDVSGRKLHLVMGNESCDLDSAVSAVTLAFVYAQRHREHDYVPILNIPRRDYPLKTEVGHLFVKCGIAEPVLLFRDDIPREVVQDVNVILVDHHVSPLAPNVTEILDHRPLEDSSPSFKQLPTLCQLDIDASVGSCATLVAQRYLAEDQPRSTSVAQLLHATIVLDTINFAPAAKRYGPKDEAMVQKLESELNRKDAQRSSLFDELVAARADISKLTLTEVLRKDMKVLQTDRQVVPLAGMPILVRDFVEKSGAEKAVREFGVESNLLVILGMYVSPADGQVQRDLALISLSGQGQFVQRVQQALMESNDPKLELRPHEVDTRFMGGCFLRQHNVQATRKHILPIVKRALLEWEADHACDCDEVYFFKEKPQLGLS
Protein: Interleukin 9 receptor (G3V8S1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MALGRCFPEGCTVEGAAVKQVSWFLIYSCVCSCVCWGVSVPAQEGGRKAGTFTCFSNSVFRIDCHWSAPEPGSRAWLLFTSNQVTDIKHKCTFWDSRCTLVLPKEEAFLPFDNFTITLHRCVMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGISFGLEPLITSLSYELAFKRQEEAWEQARLKDRIVGVTWLVLEAIELNPDTIYEARLRVQMALESYDDKTEGEYYKSHWSEWSQSVSFPSPRRKTQGLLIPRWQGSASILVAVPIFLLLTGLIHFLFRLSPKVKRIFYQNVPSPEAFFHPLYSVYHGDFQTWIGARRAGPQARQDGASAPSGDSESSIWEAIATLTYSPACSVQFPSLKWEATAPGFPGPPGSELVLPAGCLELEGQPSAYLPQEDWAPLGSARPPPLDSDSGSSDYCMLDCREEYDLSVFPEHTLSPEFTLAQPVALAVSSRA
Protein: BBSome complex member BBS5 PH domain-containing protein (Q4GYG4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell projection, cilium membrane {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000256|ARBA:ARBA00004607}.
Interaction partners:
- PTHB1 N-terminal domain-containing protein
- Bardet-Biedl syndrome 8 protein
- FG-GAP repeat protein, putative
- FG-GAP repeat protein, putative
- Uncharacterized protein
- Uncharacterized protein
- Ankyrin repeat protein
Sequence:
MPAGGDTAKSSAKSAPTLLLDRTIRFDTSLSELQEQTSRGERILMRLSPVEDTKGNSGKEGVLYVTNLRFMWHSSHRVRNNLSVGYYGVYNMSVQMVETRLRGHAEALRITARYGSNRFEFFFTHPSEDRRSRLSAVRLVWRAYDTTRIYREVRLRSCAVRDGELLLLKGERLVTRVKGVSNVSSEQGHIGTFFTTNLRLLWCSDTSAEFNISIPFLQIAAMRIQDTEFGLSLMVETTASVDSYVIGFRVDPVARLDQLFKECTSLLNAFKTHPNLGVAVTLQDVTAGNDDEVSAMLGAAEGASVGPQPRELDGENVVQEVATDAFAAYYVGIGQKGADRKPEYNASIGLAVEKLRNGVTLQDLWNVVT
Protein: Josephin-2 (EC 3.4.19.12) (Josephin domain-containing protein 2) (Q8TAC2)
Organism: Homo sapiens (Human)
Function: Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:23625928}.
Interaction partners:
- Polyubiquitin-C
- Polyubiquitin-B
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin carboxyl-terminal hydrolase isozyme L3
- COP9 signalosome complex subunit 5
- Ubiquitin carboxyl-terminal hydrolase 1
- UV excision repair protein RAD23 homolog B
- Zinc finger-containing ubiquitin peptidase 1
- Transitional endoplasmic reticulum ATPase
Sequence:
MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEEKGSWLRTD
Protein: RRM domain-containing protein (A8DYS1)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSGAVLPAVLVVPKMESVVVPIAESTVINAKDTTPSTAADNDVSPSPSEPDTDAIKMFVGQIPRQWNETDCRRLFEKYGSVFSCNILRDKSTQASKGCCFVTFYHRKDAIEAQGALHNIKVIEGMHHPVQMKPADTENRNERKLFIGQLSKKHNEENLREIFAKFGHIEDCSVLRDQDGKSRGCAFVTFTNRSCAVVATKEMHHSQTMEGCSAPLVVKFADTQKDKDVKTKSMITGSGAGSPKGGAASLLQNLNPALLQQLGGGQNYQAVASLLSLINGQQGQQQQHQQQQNVLGILGTGNPLLGNPAMAAQNQFDAITMAQIAHQQQMLALQGFAVQQGAPSQQQQGLFLAHQYSTNYSTGSPDSASNATDSSSDDNNVMNNRLTPTSKMAQYGYGPLIPRHPAQLYLQQRFPATAAAYGLAGGMAGAKTTSPVAASLANHQQIALTPFAGGAAALDHFQAMQQYALLANLQATGGVGVQATTSAAQMVGNGDVKGPDGANLFIYHLPQDFGDSDLINTFAPFGGILSAKVFIDKVTNLSKCFGFVSYENAQSATNAISAMNGFQIGSKRLKVQLKVDRGNPYNR