wanglab/gogpt-training-data huggingface dataset:
Protein: adenylate cyclase (EC 4.6.1.1) (G5EE33)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit
- Guanine nucleotide-binding protein G
- cAMP-dependent protein kinase regulatory subunit
Sequence:
MGFSSEWLEQSYLDWRHAASARLIRIVLFITSGSAFLRTLGHIPGFYALWTAVILLLSTVTIIFHILRPARIAAFQILAGIVLLLDVAFALPGYESLFPALLAVFSLYTFFSLPFYAILATSTLISIVQTCSFLLFVEPLHTNELLAIIVVHIWTNFTGIYLCSTADRLARNAFLSARNSSEAESTAEFQSNRLNKLLSSFLPYHLINQARHQITLYKPHLYNETYSQVSVAYGRLVGFESVLAQCSSIDAARVLKELDSRIERLAASNGCTRVASEGITAVCSIPGIDSQHATKLCRFSMELETLINSFRDATGADVSVCIGIDSGPVTAGVVGVSKWHYDVIGSVFDNALLMQSNATEPGVYVSNETRRFLGSTGEFELEKCPIGWKLYGHLPSPELFPVNKRFSLVTVPQAVNRVLQSIVAMNPTLKTMGTNKKRKGEKSQEKFDMQKKKVEHSTIISTLSQRFRNPGLEAEYHKETDHWFIPSLAISIFFLVVYGIYHMLVMPRLITSLALIVGALTVMFFILLMLYIDYFHTFSQFITRTSAGHAVSIILIIVILFVCGIVNTFSCPQPNAPDVCQKAHFSTYSFAMWTITTAVFVRFPSVYLAILLIISLLTYGLQIYVTRPDEFGPREFMTELDLSCFLISLVSMVFLHSRRCERLLRLDFLAVVKGIEETSMKDKLINLNNQMLLNLVPAHVAPGVIQKAGDVWHHSHQSVGIAYIAVSGFDLEGEAGINGLNYVFSHFDQAIANYKGVEKVKSANRFYIVAVGLLPDAAQNVNETPWTIGELMSTLAHFIISISQFAMENEFHVQIGVDCGSTLAFVANTDQPRYEIFGETLDRSRTLMQAAGHDTTLVSEEVFLALRPRPLRFSSQPVKVAMNLNAYELVTGLRDVSVDIPTMPREEQERHTQGMVEAQFANQSRMYDTQTSEMASSMASSFSSELRSIDGDAETDSDLEWITPETALMKDPQPQRSHRFVLKNSDYDPYREPVHRNIRAMSAEQDYRNRRIQSGSDMSDAECGGPSTSRANSRNSYRRGWRPSSKNSLRNGFGLFRKGHSDNEQSVDGIDKIEAAANRVDRMIQELNAFGDFAEIKPLEYQPFPANFGSVKSIHRAMSSACHTEYDNAESDAVISDVESNANSISQLRNSKSRQKRRWKEARRWHRDAADGDTESQCSSMAGSIDLDPIRWKSTHSIGYENEYEMQSDVEGLAFEEMAALSRDIRNNFGDFQLSTFDDIDQD
Protein: Fanconi anemia group I protein (P90790)
Organism: Caenorhabditis elegans
Interaction partners:
- Probable NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase 1 beta subcomplex subunit 8
- NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial
- Probable NADH dehydrogenase 1 alpha subcomplex subunit 12
- Probable NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Probable NADH dehydrogenase iron-sulfur protein 6, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
Sequence:
MTEIRKVVQETMVGKPEDEIQTFEKCLRLVGSNRTRKEQELGFCLMSRMIIKCSSQTLRAVQSRLANRLAHISDHFQLCGSLYTRELLVRNPQAGELHSPIVFKIILNCMDAAAQTSDPNIRGLAAELFGLRISNQNLTMLLNTLEVLLSATKIKNVSNDLLQLRTLGVSSHRDSLTSLLFEVLALSLGYASKPGLFVERKDIIQVIELGINNPKNRSVAFACLRSMCVNTKYSLIPMIGRIVSTLISELESPDVDLIKTLAFISKTFGPVTSTLYKHFYVIFTALKHPIHEQCYGEHVGNLLSSIIESAASLIKPEVFATVQKAVCESAIMHPDSSIYLQLLAAFLTLNNEYVPSPLQVARVISSRTRNTSEHSHRLRALCNVASRPRTTDLANVKAKKTLVLKEENTIQAPTAASEDLKEKEEVEQEFEEMETEDKEEEIVPVVVEKKIEEVPEASSRKKKNSESSTTATSTVAKKKKKSVVNDVKTNLLEGEASVDDILNLFDMS
Protein: Plasmodium RESA N-terminal domain-containing protein (Q8IK58)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MEEENDLNHFVLKYILVIILGVLCAEFCVMVIHIMNSRVVPRAVWPNQSLHHVLPSVRITSAKRRRMNYNDDDAYDESHYNHNSTNNGNSDKAEDIWNGIDSIFNRIMQNIKDNSYKDYPSLHRVVDYNDLSRNLSREELNAVLRGLNDDTPRNDLISIWNHVVRINRDGMVDIINSILLYVNNFVRNYKNGKLDVKEILEELKIDEKSLRLFKTSSLKEISSCDFKYYNDFYTLLNNEKKIEDIKDLINSYMKFADDTKKKIYHNYIKQFKESFEKYIEKKNNTPKESTE
Protein: Adenosine monophosphate deaminase, putative (EC 3.5.4.6) (Q38EM6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Inosine-5'-monophosphate dehydrogenase
- Inosine-5'-monophosphate dehydrogenase
- Adenylosuccinate lyase
- Adenylosuccinate synthetase
- adenine phosphoribosyltransferase
- adenine phosphoribosyltransferase
- Adenosine kinase
- Adenosine kinase
- Hypoxanthine phosphoribosyltransferase
- Hypoxanthine phosphoribosyltransferase
Sequence:
MEQQVSNRGSNSDPPASSQCEEETKQHEVSETTFCGSEFAEGSGGTLLQTVAPDAPSVRSCGSHQVPSSSKGAPFASRAQALMSGAASVVAPLSVHSGSQHTSRKGNTHNLARLAVKHNLYAVQLDGDSGGIEMQAASQYLLRAVTTREKYKSVDKGQKEGTGRLVPPVVFSFETGVAQFTDQKTEVLPWEQFYDDVIELCATMQHPDCRRACSQRLQVLEEKYNLYKLCSSNVENPDHHRHDVGVFSDCTKVDNSVYLSCMVNSELLREYIQDKVEYCGSDEVRYSADKTEVHTLSTTCDQLGFTEVEQLTIEGLGLSPPNEKQRYHYDPLDLELNRTGRNCAELLQLFLTHNTLNKGKYFAEIVKPTLSENEQRMRNPQATECIVELCGTSAEDWEQLAAWAQEHNLLRMWHNRWFVALPRRRIRSDSTKDALENHQQHLENIFLPLFTATLAPEDPKNASIVALLQNLGGFVIVSDEEERNSTFERKLRRPVEVPWSENVCDLYFAYHVWANLCSLNALRRRKGLNTLQLRAFAGNRDGQIDVLVYSYLLCDSLVNGVLLEHNPVLQYLYGAGKIGLVMMPLCNNGMGLPYMQNPFPVFFRRGLLVTLTTNQPLLFHHSKEPLIEEYGTASKLFQLSGTDACEIALNSVIVSSFPADVKALWLGDSFLQEGIQGNMLEFSKVPTCRLVLRQELWQTELNIIHQAAVRNTRGKRGAFPLPTLLSTPPPLMASGSHAGDSTEVEPSGVTLQQAVTMMQSSQMPFLARDPHTDFPRVVFLGPLERDPSDTLVVTLLHRALQLRSQYVRQHNIRDVDGRVLRSDDIEHAFRRDDTFDEDEWMFKTVEGVVVPHEVHQIPRLPKDMFHFDDFRQHVQELRAMLENAHVRNFATRRLNLLERKFMLHLAVNRSLEAGTTASKASQNRDFYQATKVDNNVRMESGMTARQLLNFIVSKANNNGDDIVAHQEGKEPQTLRQLLQELNISPSTLTVDDLNVQVDTTLGVGSAQYTPGGRDVLCTLLLNTDNQMKGRYFAELTKLTFENFEHDRFTFTENRLPIYGASPNEWGLLSDWFDTHGMASVHNRWMVQIPRIYGYLRECGKVQSFTEYIENIFKPLWTVSLHPSKDPRLFHFLNHISGFDCVEDERRHDIPLNNATKPPHEWTTEEEPPYNYYMYHVWANIYSLNEFRRRRKFSTFTFRPSCGETGPVEHLIGGFLLANAINYGVTLADDTPLQYLFYLARIGVTVSPLSNNTKVLGYLDNPFPTFFRRGLNVSLGTDSPLMFHHTQEPLLEEYSIASKVWKLSPNDMCEIARNSVLLSGFDAAFKRERLGDLFFLSSSRSNDASHTHLSDIRVAYRFETYHAEIAFLEMISTLNFPKALLTLSEERALEADFLEAVKKKEKQLGCIIEVKTEEEDIKRLEQSRAALLRQVREAEDTVEELRRQNKQLTEKLAEERARDQHAQQMRRKGLKERVVGISDPEGRRQTSSSNADMSSDHQPSLEISVLEQVAKEETNGEDATAAGQSQHLGGAKVGLTALSPTALEDTSPRSAGFISSGNVADLDDNLDTAATTSALVGMLESMWKEKPAGASHSGGHTVTGGDASSTFPPINVDAVTLSERKPSGASGSTTKRGPPPPRRTSANSAFVFPKPSGEGGSHRASLQGFANVQQAAREQEAKETGSSHRSSERGV
Protein: Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3) (Q5DTK1)
Organism: Mus musculus (Mouse)
Function: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Chondroitin sulfate synthase 1
- Chondroitin sulfate synthase 2
- Chondroitin sulfate N-acetylgalactosaminyltransferase 2
- Chondroitin sulfate N-acetylgalactosaminyltransferase 1
- Polypeptide N-acetylgalactosaminyltransferase 3
- Hexosyltransferase
Sequence:
MAVRSRRPWVSVALGLVLGFTAASWLIAPRVAELSEKRRRGSSLCSYYGRSATGPRADAQQLLPQPQSRPRLEQSPPPASHELPGPQQPEAAPGGPSFRSSPWQQPALLPQRRRGHTPEGATALPGAPAAKGEPEEEDGGAADPRKGGRPGSSHNGSGDGGAAVPTSGPGDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQSPSAALGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNTEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGRTPSFNHFQPRERNEVMEWEFLTGKLLYSAAENQPPRQSINSILRSALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQPFSKPFFREVEELDVNRLVESINSGTQSFSVISNSLKILSSLQEAKDIGGHNEKKVHILVPLVGRYDIFLRFMENFESTCLIPKQNVKLVIILFSRDAGQESIKHIELIQEYQSRYPSAEMMLIPMKGEFSRGLGLEMASSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTVQGQQVYYPIIFSQYDPKVTHMRNPPTEGDFVFSKETGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRDNRTLS
Protein: Glutaredoxin 3 (Q6EZG4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MPIQEIKSGEEVAAFIKEPSPAVLHFYASWAPSCEQVNQLLDDLLAEIALPLRAAFIDAEALPGISLNFKITAAPTLVFFSNGKEVDRIDGFVPKEIQSKVVLVASRSLSQSSSDASSTTSSTPSLTPQQEKEALNARLGALVNSQKVMVFMKGDPSAPRCGFSRTIVELLNSHKIKFGSFDIFSDEAVRQGLKEYSNWPTYPQLYFDGELIGGLDVVKEEFSDPQFIKQLPKVGENSEGGSLEDRLKKLVSSQRLMLFMKGDRETPKCGFSRTIVDLLNKARADYHTFDILEDEEVRNSPIGQLIHSSISTESSSEGLMSSRKSSWIRISFVRFQELEMIN
Protein: Tubulin alpha-1A chain (F8VRZ4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGS
Protein: Melanoregulin (Dilute suppressor protein) (Whn-dependent transcript 2) (Q6NVG5)
Organism: Mus musculus (Mouse)
Function: Probably functions as cargo-recognition protein that couples cytoplasmic vesicles to the transport machinery. Plays a role in hair pigmentation, a process that involves shedding of melanosome-containing vesicles from melanocytes, followed by phagocytosis of the melanosome-containing vesicles by keratinocytes. Functions on melanosomes as receptor for RILP and the complex formed by RILP and DCTN1, and thereby contributes to retrograde melanosome transport from the cell periphery to the center. Overexpression causes accumulation of late endosomes and/or lysosomes at the microtubule organising center (MTOC) at the center of the cell. Probably binds cholesterol and requires the presence of cholesterol in membranes to function in microtubule-mediated retrograde organelle transport. Binds phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate and phosphatidylinositol 3,5-bisphosphate, but not phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 4,5-bisphosphate. Required for normal phagosome clearing and normal activation of lysosomal enzymes in lysosomes from retinal pigment epithelium cells. Required for normal degradation of the lipofuscin component N-retinylidene-N-retinylethanolamine (A2E) in the eye. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (Probable).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:17260955}; Peripheral membrane protein {ECO:0000269|PubMed:17260955}. Melanosome membrane {ECO:0000269|PubMed:22275436, ECO:0000269|PubMed:22940130}; Lipid-anchor {ECO:0000269|PubMed:22940130}. Lysosome membrane {ECO:0000269|PubMed:22940130, ECO:0000269|PubMed:30174147}; Lipid-anchor {ECO:0000269|PubMed:22940130}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:19240024}. Note=Localizes to the inner segment and basal outer segment of rods in the retina. {ECO:0000269|PubMed:17260955}.
Interaction partners:
Sequence:
MGLRRWLRSACCCCPCRCLEEPARPEKEPLVSGNNPYSSFGATLERDDEKNLWSMPHDVSHTEADDDRILYNLIVIRNQQTKDSEEWQRLNYDIYTLRQIRREVRNRWRRILEDLGFQREADSLLSVTKLSTMSDSKNTRKAREMLLKLAEETSIFPASWELSERYLLVVDRLIALDAAEDFFKIASQMYPKKPGVPCLVDGQRKLHCLPFPSP
Protein: Ferredoxin--NADP reductase, leaf isozyme 1, chloroplastic (EC 1.18.1.2) (Leaf FNR 1) (AtLFNR1) (FNR-1) (Q9FKW6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|Ref.7}. Plastid, chloroplast thylakoid membrane {ECO:0000269|Ref.7}; Peripheral membrane protein {ECO:0000269|Ref.7}; Stromal side {ECO:0000269|Ref.7}. Note=More abundant in the membrane fraction. {ECO:0000269|Ref.7}.
Interaction partners:
- Protein TIC 62, chloroplastic
- Ferredoxin-2, chloroplastic
- Rhodanese-like domain-containing protein 4, chloroplastic
- Ferredoxin-1, chloroplastic
- Photosystem II 22 kDa protein, chloroplastic
- Assimilatory sulfite reductase
- Ferredoxin--nitrite reductase, chloroplastic
- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic
- Protein YCF54, chloroplastic
- Photosystem I reaction center subunit V, chloroplastic
Sequence:
MAAAISAAVSLPSSKSSSLLTKISSVSPQRIFLKKSTVCYRRVVSVKAQVTTDTTEAPPVKVVKESKKQEEGIVVNKFKPKNPYTGRCLLNTKITGDDAPGETWHIVFTTEGEVPYREGQSIGVIPEGIDKNGKPHKLRLYSIASSAIGDFGDSKTVSLCVKRLVYTNDGGEIVKGVCSNFLCDLKPGDEAKITGPVGKEMLMPKDPNATIIMLGTGTGIAPFRSFLWKMFFEEHEDYKFNGLAWLFLGVPTSSSLLYKEEFEKMKEKNPDNFRLDFAVSREQTNEKGEKMYIQTRMAEYAEELWELLKKDNTFVYMCGLKGMEKGIDDIMVSLAAKDGIDWLEYKKQLKRSEQWNVEVY
Protein: Pre-mRNA-processing factor 31 (P49704)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Promotes the association of the U4/U6.U5 tri-snRNP particle with pre-spliceosomes to form the mature spliceosomal complex.
Subcellular location: Nucleus.
Interaction partners:
- U4/U6 small nuclear ribonucleoprotein PRP4
- Pre-mRNA-splicing factor 8
- LSM complex subunit LSM3
- Small nuclear ribonucleoprotein G
- U4/U6 small nuclear ribonucleoprotein PRP3
- Pre-mRNA-splicing factor 6
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein Sm D2
- 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component
- Pre-mRNA-splicing helicase BRR2
Sequence:
MSSEEDYFDELEYDLADEVNEEKEDIQTKKLTTVNCQTEKFNPFEILPESIELFRTLALISPDRLSLSETAQILPKIVDLKRILQQQEIDFIKLLPFFNEIIPLIKSNIKLMHNFLISLYSRRFPELSSLIPSPLQYSKVISILENENYSKNESDELFFHLENKAKLTREQILVLTMSMKTSFKNKEPLDIKTRTQILEANSILENLWKLQEDIGQYIASKISIIAPNVCFLVGPEIAAQLIAHAGGVLEFSRIPSCNIASIGKNKHLSHELHTLESGVRQEGYLFASDMIQKFPVSVHKQMLRMLCAKVSLAARVDAGQKNGDRNTVLAHKWKAELSKKARKLSEAPSISETKALPIPEDQPKKKRAGRKFRKYKEKFRLSHVRQLQNRMEFGKQEQTVLDSYGEEVGLGMSNTSLQQAVGATSGSRRSAGNQAKLTKVMKHRISEANQQADEFLISLGHNTEQPNLSPEMVQMHKKQHTNPEEETNWFSGHG
Protein: 17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6) (17-beta-HSD6) (EC 1.1.1.105) (EC 1.1.1.209) (EC 1.1.1.239) (EC 1.1.1.53) (EC 1.1.1.62) (3-alpha->beta-hydroxysteroid epimerase) (3-alpha->beta-HSE) (Oxidative 3-alpha hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 6) (O14756)
Organism: Homo sapiens (Human)
Function: NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
Subcellular location: Microsome membrane {ECO:0000269|PubMed:11360992}; Peripheral membrane protein {ECO:0000269|PubMed:11360992}; Lumenal side {ECO:0000269|PubMed:11360992}. Early endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Lumenal side {ECO:0000305}.
Interaction partners:
- Aldo-keto reductase family 1 member C3
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1
- Steroid 17-alpha-hydroxylase/17,20 lyase
- 17-beta-hydroxysteroid dehydrogenase type 3
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
- Dehydrogenase/reductase SDR family member 11
- Polyprenal reductase
- 17-beta-hydroxysteroid dehydrogenase type 1
Sequence:
MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYLPTSLADYILTRSWPKPAQAV
Protein: Dynein axonemal assembly factor 1 (Leucine-rich repeat-containing protein 50) (Q7ZV84)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Cilium-specific protein required for the stability of the ciliary architecture. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli (Probable).
Subcellular location: Cell projection, cilium {ECO:0000250}.
Interaction partners:
- Axonemal dynein light intermediate polypeptide 1
- Zinc finger MYND domain-containing protein 10
- Cilia- and flagella-associated protein 298
- Dynein, axonemal, intermediate chain 1, paralog 1.
- Radial spoke head protein 9 homolog
- Dynein axonemal assembly factor 19
- Coiled-coil domain-containing protein 40
- Radial spoke head component 4A.
- Dynein, axonemal, heavy chain 11.
- Dynein axonemal assembly factor 3
Sequence:
MKTKMIVSTSMNAGEGTRTEAEDTSKGVASLADLDSQSAAAEVSESDIKPSGPRITKDFLREHCKKNKLYLTPRLNDTLYLHFKGFSCIEGLEEYTGLRCLWLECNGIRKIENLENQTELRCLFLHQNLIHTLENLEPLSKLCTLNVSNNYIKVIENISSLSDLSTLQISHNTLGNVCDMEELSHCPSISVLDLSHNRISDPALVNILEKMPDLRVLNLMGNEVIKKIPNYRKTLIVRLKQLTYLDDRPVFPKDRACAEAWAAGGLEGEQKEREMWQTRERRKIQESLDAMTAIRETALKRRQDRELSEKGIIEFPSPVAEDQSPHDEISDIEPAESDSDSETTQEQTDASPSPSEMDHNFNSASDDSDQSQPQPNESVHSSFDEEQIRQSATWGLKPKEEKNQILSIYTKPSQSDQRVLISVSGPGALVTELISEDEIESINLSDEPVLTIDDLPDLEDEENSHILPITSQSGMRPKIEVISSIDTESEAVRSLYPWPHSDAVALDQSQQLISVSTTRNSVKQQSTAFTSLAEAGDDVPKAAEKRKTVLIEELD
Protein: Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein) (Q2UK72)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Upf1 domain-containing protein
- ATP-dependent RNA helicase eIF4A
- Uncharacterized protein
- PAN2-PAN3 deadenylation complex subunit PAN3
- PAN2-PAN3 deadenylation complex catalytic subunit pan2
- LsmAD domain-containing protein
- Uncharacterized protein
- ATP-dependent RNA helicase dhh1
- Elongation factor 1-alpha
- Uncharacterized protein
Sequence:
MSADASTTPAADSNVTSTPETSTTPAAPAPEVTAVESTTAPNASQPHSASLYVGELDPSVTEAMLYELFSSIGQVASIRVCRDAVTRRSLGYAYVNYNNTADGERALEDLNYTLIKGKPCRIMWSQRDPALRKTGQGNVFIKNLDSAIDNKALHDTFAAFGNILSCKVAQDEFGNSKGYGFVHYETAEAANNAIKHVNGMLLNDKKVFVGHHISKKDRQSKFEEMKANFTNVYIKNIDQDVTEEEFRELFEKFGEITSATLSRDQEGKSRGFGFVNFSTHESAQAAVDEMNEKEIRTQKLYVGRAQKKHEREEELRKQYEAARLEKASKYQGVNLYVKNLTDDVDDEKLRELFGPYGTITSAKVMRDTNIERTQTPESDKEKENKEATKENEKESSEAEKAEKTEEKPADSGDEKKEDKESKKADKKGLGKSKGFGFVCFSSPDEASKAVTEMNQRMVNGKPLYVALAQRKDVRRSQLEASIQARNTIRQQQAAAAAGMPQPYMQPAVFYGPGQQGFIPGQRGGIAFPPQPGMVMAGIPGGRPGQYPGPFPGQQGGRGMGPNQQLPPNFQGIPMGAMQGPVPNGMGYPQGMAQVQFGRGAGGRGQVPGMPNMGQGMRGPGYGQGRGGVPVQQGQMRPGQGGRGQNAAQAPAGRPEEAVAGGLTAQALSAAPPPQQKQMLGEALYPKIQAQQPELAGKITGMLLEMENTELLSLLEDEEALRAKVDEALNVYDEYMKNKGGESEATGEAAKPKEAAKETSTEENKS
Protein: ETS translocation variant 5 (Q9CXC9)
Organism: Mus musculus (Mouse)
Function: Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}.
Interaction partners:
- DET1 homolog
- E3 ubiquitin-protein ligase COP1
- Solute carrier family 45 member 3
- B-cell CLL/lymphoma 6 member B protein
- Zinc finger and BTB domain containing 16
- Transmembrane protease serine 2
Sequence:
MDGFCDQQVPFMVPGKSRSEDCRGRPLIDRKRKFVDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGAKYGEKCLYNYCAYDRKPPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTSGLTPGAGPVQGVGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPSHPFPPQSGVPGDSRPSYHRQMSEPIVPAAPPPLQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYCADSEVPNCQSSYMRGGYFSSSHEGFPYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECPLNEEDTLPLTHFEDNPAYLLDMDRCSSLPYTEGFAY
Protein: Slr1098 protein (P72742)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- Uncharacterized protein slr1565
- Uncharacterized protein slr1417
- Uncharacterized membrane protein sll0875
- Slr0876 protein
- Thylakoid protein sll1769
- Sll0064 protein
- Phycocyanobilin lyase subunit alpha
- Ycf51-like protein
- Slr1687 protein
- Segregation and condensation protein A
Sequence:
MRKYGAMRNQDDLLLEDSWVDPLDQLDDDVAPPPPDPDEMLVLLTSREAPQRMLAARAFCEIADRRAVEPLINLLGDSCPLVRVSAAYALGRNTDPTIVEPLIQSLQTDFNGYVRKGLVWALGNCGDRRALAPLIHALKTDISAVRLWSASSLPNIAKLAYEDVIATIPPLIEGLRRDKMAAVRSNCAWAVGQLCRELPSNVVYATAIDALLEALVEDEDFGVKEDAKSALLRLGDARGLQMIEDLEMDGLI
Protein: Heme exporter protein B (Cytochrome c-type biogenesis protein CcmB) (P0ABL8)
Organism: Escherichia coli (strain K12)
Function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Cytochrome c-type biogenesis protein CcmE
- Heme exporter protein D
- Cytochrome c biogenesis ATP-binding export protein CcmA
- Heme exporter protein C
- Cytochrome c-type biogenesis protein CcmF
- Thiol:disulfide interchange protein DsbE
- Cytochrome c-type biogenesis protein CcmH
- Cytochrome c-type protein NapC
- Acetylornithine/succinyldiaminopimelate aminotransferase
- Periplasmic nitrate reductase, electron transfer subunit
Sequence:
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWMVTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVLLSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ
Protein: Uncharacterized protein (Q57X59)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRSVIRSCVIFPAAGVAMRHDSSQQWVLNVMYGTGLAPRYGSWKSFGVGDALKENDTPVLYCKALVHASGGGRRARDWVAGCSAALFPSYELLKIAMRHNSSEEDVERYRRHLVETLEKAQGPQTGSANDAGNVTSGEDGSKSDTENDTDINMRLSQMPEVRCFVYDAMRAACFHRYKKVPEEQRVKLFTVAARLGLDEGTTMAIWRLVEKEGIVARDKQRALESPWND
Protein: RNA helicase (EC 3.6.4.13) (D6XG53)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Sas10 C-terminal domain-containing protein
- Nucleolar RNA binding protein, putative
- Sm protein F
- Small nuclear ribonucleoprotein E
- G-patch domain-containing protein
- Sm protein G
- Small nuclear ribonucleoprotein Sm D2
- Sm protein B
- U2 small nuclear ribonucleoprotein B, putative
- Small nuclear ribonucleoprotein SmD1
Sequence:
MLSKRNREGSRGAMGCGEKNPYTGRVLSSRYHALRGVREKLPIFAAKQKIQRLISRYQTLLLVGETGSGKTTQVPQFVLEMNPEHAIACTQPRRVAAISVSERVAEELDVTLGEEVGYCIRFDDTSSDRTRLKYLTDGMLLREAMGDPMLQRYSVIILDEAHERTVHTDILIGAVKDLLHRRPDLRVVVMSATLEERRFQSYFPEAPLVHVSGRMYDVEVYNSRLPEANYLEASIRTAMQIHLYEGPGDILIFLTGEDEIEQAVERLRLGIPMAEHTNADCHKGPVAVLPLYSALPPKEQRKVFQAAPEGTRKIVVATNVAETSLTIDGVVFVIDSGFSKQKVYNPKLRVESLLVTPISQASARQRCGRAGRTRPGKCFRLYTAKAFDTLLQQQTYPEILRCNLGSVILHMKMMGIEDLVNFDFVEPPAPETLMRALELLNYLGAINDDGDMTKFGRRVADFPLEPEMAAMLLHSPEYGCSDDIARICAMMSVQSPFVTPRNDQRGCAMRCRDQFYHPTGDHLALLNVFNAFYEGSNQSGSWASENYLNPRVMKQSVSIYRQLIGIMRRLNLSICSTYSAAQWGGAGDGESDEYANEVRRAVLRGYFTKVALSLPTKNQFLTLKDNVKCLLFPSTFLNRRPKFVVFNELVLTTNTYIRTVTSVSDEWLLEVNPLYFDPSEFEGVSRQVFEELHRRNNRNNAAERDQNKDCLTGHKRRRGGDAPDNGDDDDDDDSS
Protein: IRF tryptophan pentad repeat domain-containing protein (Q3U9K6)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
METPKPRILPWLVSQLDLGQLEGVAWLDESRTRFRIPWKHGLRQDAQMADFGIFQAWAEASGAYTPGKDKPDVSTWKRNFRSALNRKEVLRLAADNSKDPYDPHKVYEFVTPGARDFVHLGASPDTNGKSSLPHSQENLPKLFDGLILGPLKDEGSSDLAIVSDPSQQLPSPNVNNFLNPAPQENPLKQLLAEEQWEFEVTAFYRGRQVFQQTLFCPGGLRLVGSTADMTLPWQPVTLPDPEGFLTDKLVKEYVGQVLKGLGNGLALWQAGQCLWAQRLGHSHAFWALGEELLPDSGRGPDGEVHKDKDGAVFDLRPFVADLIAFMEGSGHSPRYTLWFCMGEMWPQDQPWVKRLVMVKVVPTCLKELLEMAREGGASSLKTVDLHISNSQPISLTSDQYKAYLQDLVEDMDFQATGNI