wanglab/gogpt-training-data huggingface dataset:
Protein: Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) (P70404)
Organism: Mus musculus (Mouse)
Function: Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Subcellular location: Mitochondrion.
Interaction partners:
- Isocitrate dehydrogenase subunit alpha, mitochondrial
- Isocitrate dehydrogenase subunit
- Aconitate hydratase, mitochondrial
- Isocitrate dehydrogenase, mitochondrial
- Isocitrate dehydrogenase cytoplasmic
- 2-oxoglutarate dehydrogenase complex component E1
- Succinate--CoA ligase subunit alpha, mitochondrial
- Cytoplasmic aconitate hydratase
- 2-oxoglutarate dehydrogenase-like, mitochondrial
- Dihydrolipoyl dehydrogenase, mitochondrial
Sequence:
MALKVAIAAGGAAKAMLKPTLLCRPWEVLAAHVAPRRSISSQQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAHYPQITFDSMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSQAIQDIIRHIRIINGRAVEA
Protein: Oxysterol binding protein like 5 (E9PIJ6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDMEPNGPSLPRDEGPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKET
Protein: Thioredoxin-1 (TR-1) (Trx-1) (O14463)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
Interaction partners:
- Peroxiredoxin tpx1
- Thioredoxin reductase
- Glutathione reductase
- AP-1-like transcription factor
- Probable peptide methionine sulfoxide reductase
- Glutathione peroxidase-like peroxiredoxin gpx1
- Peroxisomal membrane associated protein 20
- Glutaredoxin-2
- Thioredoxin-like protein 1
- Glutaredoxin-1
Sequence:
MVKQVSDSSEFKSIVCQDKLVVVDFFATWCGPCKAIAPKFEQFSNTYSDATFIKVDVDQLSEIAAEAGVHAMPSFFLYKNGEKIEEIVGANPAKLEASIKANL
Protein: Ethylene-responsive transcription factor ERF055 (Q9SKW5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DUF241 domain protein, putative
- Uncharacterized protein AT4g35200
- 2-Cys peroxiredoxin BAS1, chloroplastic
- AT4G23670 protein
- Defensin-like protein 99
- HVA22-like protein i
Sequence:
MADLFGGGHGGELMEALQPFYKSASTSASNPAFASSNDAFASAPNDLFSSSSYYNPHASLFPSHSTTSYPDIYSGSMTYPSSFGSDLQQPENYQSQFHYQNTITYTHQDNNTCMLNFIEPSQPGFMTQPGPSSGSVSKPAKLYRGVRQRHWGKWVAEIRLPRNRTRLWLGTFDTAEEAALAYDRAAFKLRGDSARLNFPALRYQTGSSPSDTGEYGPIQAAVDAKLEAILAEPKNQPGKTERTSRKRAKAAASSAEQPSAPQQHSGSGESDGSGSPTSDVMVQEMCQEPEMPWNENFMLGKCPSYEIDWASILS
Protein: Uncharacterized transporter C1683.12 (Q9P6J0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Small ribosomal subunit protein mS43
- Adenosylhomocysteinase
- Inheritance of peroxisomes protein 2
Sequence:
MSTMEEEKVISKSTSVDISEGTFDDITIEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAAVSVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLGICEGGFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNWGWLYIIEGLISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQRQKYMGSPNFDWTQFRKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGISVYVICLLSDRTNIRGWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVALNITWINNNMAPHYRRATALGCNQTIGNLAGVIAGQVYRSSPYKLGHGFALGCTVVGTLTATAMRFYLQRQNKIKQEILNGERVDEKKERDGCDALDFVYVL
Protein: Calponin-like domain protein (F4HWC3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
- Uncharacterized protein
- AT-hook motif nuclear-localized protein 1
- Protein kinase superfamily protein
- B-box type zinc finger family protein
- Winged-helix DNA-binding transcription factor family protein
- Cytosolic sulfotransferase 11
- Actin-depolymerizing factor 3
Sequence:
MPVEVERDQGEVSVKVDFENATEIKPEVVVSATKEDVVNGISHGGSNNGNGNDTDGSYDFITENDTVGDDFVESDYVKPVDDANVEKDLKEGENVKVDAPSIADDDVLGVSQDSQTLEKSELESTDDGPEEVVEIPKSEVEDSLEKSVDQQHPGNGHLESGLEGKVESKEEVEQLHDSEVGSKDLTKNNVEEPEVEIESDSETDVEGHQGDKIEAQEKSDRDLDVSQDLKLNENVEKHPVDSDEVRESELVSAKVSPTEPSDGGMDLGQPTVTDPAETINGSESVNDHVGSEPVTVLEPVSVENGHPPVESELERSSDVPFTSVAEKVNASDGEVLPDSGTVDVVVSEVSSDVPAETQALNAISLDSQPSGKDSVVENGNSKSESEDSKMQSEIGAVDDGSVSDGSINTHPESQDASDPTCDQGGKQHISSEVKEVLDAPASEEISDAVIVAKDNGSEAAISDGLSCTNQQGSESDEISGLVEKLPSHALHEVVSSANDTSVIVSDDTKSQGLSEDHGVDTNQTIQDDCSAELEEVTDVNVKHAPNEKVQGDNSEGNLNVGGDVCLNSAEEAKELPTGDLSGNASHESAETLSTNIDEPLSLLDTKTAVSDFAESSAGVAGEIDAVAMESEAAQSIKQCAEAHVAPSIIEDGEIDREVNCGSEVNVTKTTPVAVREDIPPKEVSEMEESDVKERSSINTDEEVATASVASEIKTCAQDLESKVVTSTDTIHTGAKDCVDSQPAENKEGNVVDRTDDKVASTGEVSVLDASEGLTVAAEIEKRPFYFLPRVPRYDDEKLAEQLKHAEEQVDQKTQNRDALRADIQKIRAICKDYDISYKAVMAEERSARKAMHSKRQEIEALQSMISRVKSAASVDDIDSRVRNMEHTMQHTTLSLNEEKGFMREIKQLKQLREQISSSMGTKDEVKQALDEKEKTEERLKVLRKELDALRNDLSKAEEITKAAKKKCDGEWEAQSKLQEQFRAADAVRQEAFVHLQDLKKQQREKNKYFFKYRDNSRAASEMALKKDRAALQSLCSDQVENFMNMWNNDDEFRKYYVKSNTRSTFRRLGTLDGRSLGPDEEPPRITYAPRTDKLRTSSDRAEKHEAVPAQKEKVVKFEGSKVENNGKEVAKPTEQKSQTTKSKKAVKPDQPPSIVTELVSGKEEIEKSATPEEEEPPKLTKEEEELIKKEEEKRKQKEAAKMKEQHRLEEIAKAKEAMERKKKREEKAKARAVLKAQKEAEEREKEREKKLRKKERRKGIFTSEETATENPIPTAETVVETPREIETPKKQTVEESQQMKKSHKPSSQFLKQNKSKSVPLPLRNRGSKRKLRQWMWIGLIVVIIIALFLLGNANLSSPANLWFT
Protein: GM01959p (Q86P95)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGNKIINMPAARIGTQWLVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEEQSDSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTSNANNKAIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAESGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEKGYYK
Protein: Probable acyl-CoA dehydrogenase FadE10 (EC 1.3.-.-) (P9WQF7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable fatty-acid-CoA ligase FadD34
- Probable fatty oxidation protein FadB
- Electron transfer flavoprotein subunit alpha
- Electron transfer flavoprotein subunit beta
Sequence:
MAQQTQVTEEQARALAEESRESGWDKPSFAKELFLGRFPLGLIHPFPKPSDAEEARTEAFLVKLREFLDTVDGSVIERAAQIPDEYVKGLAELGCFGLKIPSEYGGLNMSQVAYNRVLMMVTTVHSSLGALLSAHQSIGVPEPLKLAGTAEQKRRFLPRCAAGAISAFLLTEPDVGSDPARMASTATPIDDGQAYELEGVKLWTTNGVVADLLVVMARVPRSEGHRGGISAFVVEADSPGITVERRNKFMGLRGIENGVTRLHRVRVPKDNLIGREGDGLKIALTTLNAGRLSLPAIATGVAKQALKIAREWSVERVQWGKPVGQHEAVASKISFIAATNYALDAVVELSSQMADEGRNDIRIEAALAKLWSSEMACLVGDELLQIRGGRGYETAESLAARGERAVPVEQMVRDLRINRIFEGSSEIMRLLIAREAVDAHLTAAGDLANPKADLRQKAAAAAGASGFYAKWLPKLVFGEGQLPTTYREFGALATHLRFVERSSRKLARNTFYGMARWQASLEKKQGFLGRIVDIGAELFAISAACVRAEAQRTADPVEGEQAYELAEAFCQQATLRVEALFDALWSNTDSIDVRLANDVLEGRYTWLEQGILDQSEGTGPWIASWEPGPSTEANLARRFLTVSPSSEAKL
Protein: ABC transporter C family MRP4 (EC 7.-.-.-) (Multidrug resistance-associated protein 4) (ZmMRP4) (Protein LOW PHYTIC ACID 1) (A7KVC2)
Organism: Zea mays (Maize)
Function: ABC transporter that may affect phytic acid transport and compartmentalization. May function directly or indirectly in removing phytic acid from the cytosol or in vesicle trafficking. Required for phytic acid accumulation in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Inositol-3-phosphate synthase
- Inositol-tetrakisphosphate 1-kinase 1
- Inositol 3-kinase
- Phytase
- Phytase
Sequence:
MPPSFPSLPLPEAVAATAHAALLALAALLLLLRAARALASRCASCLKAPRRRGGPAVVVGDGAGGALAAATAGAWHRAVLASCAYALLSQVAVLSYEVAVAGSRVSARALLLPAVQAVSWAALLALALQARAVGWARFPALVRLWWVVSFALCVVIAYDDSRRLIGQGARAVDYAHMVANFASVPALGFLCLVGVMGSTGLELEFTEDGNGLHEPLLLGRQRREAEEELGCLRVTPYADAGILSLATLSWLSPLLSVGAQRPLELADIPLLAHKDRAKSCYKAMSAHYERQRLEYPGREPSLTWAILKSFWREAAVNGTFAAVNTIVSYVGPYLISYFVDYLSGNIAFPHEGYILASIFFVAKLLETLTARQWYLGVDIMGIHVKSGLTAMVYRKGLRLSNASRQSHTSGEIVNYMAVDVQRVGDYAWYFHDIWMLPLQIILALAILYKNVGIAMVSTLVATVLSIAASVPVAKLQEHYQDKLMASKDERMRKTSECLKNMRILKLQAWEDRYRLQLEEMRNVECRWLRWALYSQAAVTFVFWSSPIFVAVITFGTCILLGGQLTAGGVLSALATFRILQEPLRNFPDLISMMAQTRVSLDRLSHFLQQEELPDDATINVPQSSTDKAVDIKDGAFSWNPYTLTPTLSDIHLSVVRGMRVAVCGVIGSGKSSLLSSILGEIPKLCGHVRISGTAAYVPQTAWIQSGNIEENILFGSQMDRQRYKRVIAACCLKKDLELLQYGDQTVIGDRGINLSGGQKQRVQLARALYQDADIYLLDDPFSAVDAHTGSELFKEYILTALATKTVIYVTHQVEFLPAADLILVLKDGHITQAGKYDDLLQAGTDFNALVSAHKEAIETMDIFEDSDSDTVSSIPNKRLTPSISNIDNLKNKMCENGQPSNTRGIKEKKKKEERKKKRTVQEEERERGKVSSKVYLSYMGEAYKGTLIPLIILAQTMFQVLQIASNWWMAWANPQTEGDAPKTDSVVLLVVYMSLAFGSSLFVFMRSLLVATFGLAAAQKLFIKMLRCVFRAPMSFFDTTPSGRILNRVSVDQSVVDLDIAFRLGGFASTTIQLLGIVAVMSKVTWQVLILIVPMAVACMWMQRYYIASSRELTRILSVQKSPVIHLFSESIAGAATIRGFGQEKRFMKRNLYLLDCFARPLFSSLAAIEWLCLRMELLSTFVFAFCMAILVSFPPGTIEPSMAGLAVTYGLNLNARMSRWILSFCKLENRIISVERIYQYCRLPSEAPLIIENCRPPSSWPQNGNIELIDLKVRYKDDLPLVLHGVSCMFPGGKKIGIVGRTGSGKSTLIQALFRLIEPTGGKIIIDNIDISAIGLHDLRSRLSIIPQDPTLFEGTIRMNLDPLEECTDQEIWEALEKCQLGEVIRSKEEKLDSPVLENGDNWSVGQRQLIALGRALLKQAKILVLDEATASVDTATDNLIQKIIRSEFKDCTVCTIAHRIPTVIDSDLVLVLSDGKIAEFDTPQRLLEDKSSMFIQLVSEYSTRSSCI
Protein: Inward rectifier potassium channel irk-1 (P52192)
Organism: Caenorhabditis elegans
Function: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior.
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Perikaryon {ECO:0000269|PubMed:23152612}. Cell projection {ECO:0000269|PubMed:23152612}. Note=Detected in perikarya and neurites of HSNs.
Interaction partners:
- Probable G-protein coupled receptor egl-47
- G protein-coupled receptor EGL-6 isoform b
- Potassium voltage-gated channel subfamily KQT member 1
Sequence:
MTLSVPDCAEMNRIRMSNHRKMSLGSAPLIANGRPSPPPRRTSLAESIRTLAFTARRNSSPLYRKSTKKLKKSRLVGKNGICNVYNTNVPKKDRQYLRDIFTTMIDVKWRWMLMLFASAFVLSWSIFGTTYYLIALVHGDLSLPTPVNHTACVMNLDSVYSSFLFAVETHHTIGYGHRYITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPKKRAETIIFSDKAVICLRDGQLCFLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKVGPSIADDDRLFLVWPTTLCHVIDSRSPLYNYNQQTLMSAQFEIIVLLEGIVESTGMTAQAKTSYLPSEVLWGHRFRKLVTYQRSNGSYQIDYDLFHSTYPVRTPAMSPAEFYSSKPNLKDYYCHDSHEHKLEDNRSSDSTPLPSPSPYSYPSTPLNHFQSSSNSPVFSNNHSKFNTEAVTCEAGMLCPPTIVVQCPSTCASPNHMRRTRNQMDKSRTSSSCDLTRPSTALSDLEEECSDSGSPTKCQSPPVVPIHIEIVSET
Protein: Poly [ADP-ribose] polymerase 2 (PARP-2) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (Protein ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (Q11207)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Poly
- Probable poly
- ATP-dependent DNA helicase 2 subunit KU80
- Poly [ADP-ribose] polymerase 1
- ATP-dependent DNA helicase 2 subunit KU70
- Protein ADP-ribosyltransferase PARP3
- DNA-repair protein XRCC1
- DNA excision repair protein ERCC-1
- Probable inactive poly [ADP-ribose] polymerase SRO1
- Transcription initiation factor TFIID subunit 4
Sequence:
MANKLKVDELRLKLAERGLSTTGVKAVLVERLEEAIAEDTKKEESKSKRKRNSSNDTYESNKLIAIGEFRGMIVKELREEAIKRGLDTTGTKKDLLERLCNDANNVSNAPVKSSNGTDEAEDDNNGFEEEKKEEKIVTATKKGAAVLDQWIPDEIKSQYHVLQRGDDVYDAILNQTNVRDNNNKFFVLQVLESDSKKTYMVYTRWGRVGVKGQSKLDGPYDSWDRAIEIFTNKFNDKTKNYWSDRKEFIPHPKSYTWLEMDYGKEENDSPVNNDIPSSSSEVKPEQSKLDTRVAKFISLICNVSMMAQHMMEIGYNANKLPLGKISKSTISKGYEVLKRISEVIDRYDRTRLEELSGEFYTVIPHDFGFKKMSQFVIDTPQKLKQKIEMVEALGEIELATKLLSVDPGLQDDPLYYHYQQLNCGLTPVGNDSEEFSMVANYMENTHAKTHSGYTVEIAQLFRASRAVEADRFQQFSSSKNRMLLWHGSRLTNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADMFSKSANYCYANTGANDGVLLLCEVALGDMNELLYSDYNADNLPPGKLSTKGVGKTAPNPSEAQTLEDGVVVPLGKPVERSCSKGMLLYNEYIVYNVEQIKMRYVIQVKFNYKH
Protein: Putative mitochondrial translation system component PET127 (P32606)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Could be a component of the mitochondrial translation system with a role in promoting accuracy of translational initiation.
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- ATP-dependent RNA helicase SUV3, mitochondrial
- DNA-directed RNA polymerase, mitochondrial
- mRNA-binding protein PUF3
- Exoribonuclease II, mitochondrial
- Uncharacterized protein YOR015W
Sequence:
MGFYNCRFLSRRLSVEPCRIGSAAKSYQQRSIYHFGAALTNAPSGRETPDKLRSDLHSALEMVDEIYDTNSTVEDIGNKEKGGRQKYTEEMDKAINLLKTNIKKEYRHDKYLERTKVGTYPGRRTYPGRRTYPARRTYPASRTYSDSNSYTFRINVQKIRHALVRYNQDGVQKHNQKPPRIGHGLTRVLYQPLSLQKLRDNRSRMYNFDPAVENINPEYLEKKSEKDVNTDSSGEGQSKPIFITPHKDESLLKVAKEHRKKYISSSSSMTSVLSQLHYLLSNFRRLNIIDSSISKNFPQKNCNYSESAYFPSAVILRKKRNGICSIDSDRSLDREIVLSVLGHYLEDFLTEKSLKNSSKSENYHYSSIDEFIVRSQLDAYDPNLPGTGVFDLKTRAVSAIRYDLSHVESNNNQTGYEIDKVYGEFESLEREYFELIRSALLKYSLQARIGKMDGIFVAYHNISKMFGFQYLPLDELDYIIHSSYNSKFDSLLKEKNDITKGIYGEEDYILHYDRDDRKIACLVANREFKMSMNLFSNILKHVEQLLNSSNTKWEKCKIMLKTEVEEKRSKSGRFFNEPVLNIVALPLSPEYEDKSLLVKDTSNEQLTEELLNLRSYNENLLEEHLNSLVGFKVNVKHFYHHHPNTTHLPDFALKKNDILDTESRKYISDMMKRDWYKDIPSTQTPNFFHASDVSTWEVNSTFTDINDKQILRKLYFKYLDVKLNALKNQVITRQEPDMSKKDEIMNRIKSLQARNDHRDNGSNKRYSNFGPTRLQTKLRAYAKKGALRRKLLERSNKFHI
Protein: V-type ATPase assembly factor pkr1 (Q9P7Y3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V(0).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein F
- LSM complex subunit lsm2
- LSM complex subunit lsm3
- UPF0587 protein C2D10.03c
- LSM complex subunit lsm7
- LSM2-LSM8 complex subunit lsm8
- Splicing factor saf5
Sequence:
MSYWVELWESIFTPGVTPVLAKSAHVACGALVAVFLGLYIGTKSIHCLILFFLAICLWLSLTWFLVELAHARVNNDLQMSSQSANKNDDNSNNQNPSNNKEMSDKESDSATTTQTFSVPEELLRARTTANNS
Protein: Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) (Vesicle-docking protein SEC34 homolog) (p94) (Q96JB2)
Organism: Homo sapiens (Human)
Function: Involved in ER-Golgi transport.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:11292827}; Peripheral membrane protein {ECO:0000269|PubMed:11292827}. Note=Associated with the peripheral membrane of cis/medial cisternae.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 7
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 2
- Conserved oligomeric Golgi complex subunit 4
- Coatomer subunit beta
- Vacuolar protein sorting-associated protein 52 homolog
- Golgi SNAP receptor complex member 2
Sequence:
MAEAALLLLPEAAAERDAREKLALWDRRPDTTAPLTDRQTDSVLELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTEDILLKGFTSLGMEEERIETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILNDVNSALQHLESLQKQYLFVSNKTGTLHEACEQLLKEQSELVDLAENIQQKLSYFNELETINTKLNSPTLSVNSDGFIPMLAKLDDCITYISSHPNFKDYPIYLLKFKQCLSKALHLMKTYTVNTLQTLTSQLLKRDPSSVPNADNAFTLFYVKFRAAAPKVRTLIEQIELRSEKIPEYQQLLNDIHQCYLDQRELLLGPSIACTVAELTSQNNRDHCALVRSGCAFMVHVCQDEHQLYNEFFTKPTSKLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILKNEVLEDHVQNNAEQLGAFAAGVKQMLEDVQERLVYRTHIYIQTDITGYKPAPGDLAYPDKLVMMEQIAQSLKDEQKKVPSEASFSDVHLEEGESNSLTKSGSTESLNPRPQTTISPADLHGMWYPTVRRTLVCLSKLYRCIDRAVFQGLSQEALSACIQSLLGASESISKNKTQIDGQLFLIKHLLILREQIAPFHTEFTIKEISLDLKKTRDAAFKILNPMTVPRFFRLNSNNALIEFLLEGTPEIREHYLDSKKDVDRHLKSACEQFIQQQTKLFVEQLEEFMTKVSALKTMASQGGPKYTLSQQPWAQPAKVNDLAATAYKTIKTKLPVTLRSMSLYLSNKDTEFILFKPVRNNIQQVFQKFHALLKEEFSPEDIQIIACPSMEQLSLLLLVSK
Protein: Meiosis-specific protein ASY1 (Protein ASYNAPTIC 1) (AtASY1) (F4HRV8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for normal meiosis in male and female gametophytes. Plays a crucial role in coordinating the activity of DMC1, a key member of the homologous recombination machinery. Acts at the interface between the developing chromosome axes and the recombination machinery to ensure DMC1-mediated interhomolog recombination.
Subcellular location: Chromosome {ECO:0000269|PubMed:12186950}. Nucleus {ECO:0000269|PubMed:12186950}. Note=During interphase-early leptotene, distributed as numerous punctuate foci throughout the chromatin. At zygotene and pachytene, shows a continuous localization along chromosomal axes. {ECO:0000269|PubMed:12186950}.
Interaction partners:
- Meiosis-specific protein ASY3
- Meiotic recombination protein DMC1 homolog
- DNA mismatch repair protein MSH4
- Meiotic recombination protein SPO11-1
- DNA repair protein RAD51 homolog 1
- E3 ubiquitin-protein ligase CCNB1IP1 homolog
- Synaptonemal complex protein 2
- Synaptonemal complex protein 1
- Hsp70-Hsp90 organizing protein 1
- Meiotic recombination protein SPO11-2
Sequence:
MVMAQKLKEAEITEQDSLLLTRNLLRIAIFNISYIRGLFPEKYFNDKSVPALDMKIKKLMPMDAESRRLIDWMEKGVYDALQRKYLKTLMFSICETVDGPMIEEYSFSFSYSDSDSQDVMMNINRTGNKKNGGIFNSTADITPNQMRSSACKMVRTLVQLMRTLDKMPDERTIVMKLLYYDDVTPPDYEPPFFRGCTEDEAQYVWTKNPLRMEIGNVNSKHLVLTLKVKSVLDPCEDENDDMQDDGKSIGPDSVHDDQPSDSDSEISQTQENQFIVAPVEKQDDDDGEVDEDDNTQDPAENEQQLARVKDWINSRHLDTLELTDILANFPDISIVLSEEIMDQLVTEGVLSKTGKDMYIKKRDKTPESEFTFVKEEADGQISPGKSVAPEDYLYMKALYHSLPMKYVTITKLHNMLDGEANQTAVRKLMDRMTQEGYVEASSNRRLGKRVIHSSLTEKKLNEVRKVLATDDMDVDVTETINKTNGPDAKVTADVSTCGGIHSIGSDFTRTKGRSGGMQQNGSVLSEQTISKAGNTPISNKAQPAASRESFAVHGGAVKEAETVNCSQASQDRRGRKTSMVREPILQYSKRQKSQAN
Protein: Heat shock factor 2 (Heat shock transcription factor 2) (Q8AWA0)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKQNSNVPAFLTKLWTLVEDSDTNEFICWSQEGNSFLVMDEQRFSKDILPKFFKHNNMASFVRQLNMYGFRKVMHIDTGIVKQERDGPVEFQHHYFKHGQDDLLENIKRKVSNARPNDTKIRQEDLSNILASVQNVHGKQESIDSRLNTLKRDNEGLWREISDLRQKHSQQQQIIKKLIQFIVTLVQKNRMSLKRKRPILLNSNGKKPKYIHEIYDDPPLDHNKPSVSGLKSADLTDDVVICDVTDDDTEITEGPSRALDQSDVEIVGVFNNNTVSQTDSADSIGQTNSLVIEPEETTISTYDSLPTSSTLQLNKQSGLSLEDPMKMMDSILNESGAISQNINLLGKVELMDYLDSIDCSLEDFQAMVYGKQFSIDPDILEATEGSGGPKENAGLLSKGDKSSFSADNQLVQYTSCPLLAFLDGCTPLATEADSSTATELGDSLLQHNTEVPTDLLEPDKEPPRSSLIRLEPLTEAEASESTLFYLCELNPEGDTTDSTQLEIYDLFPVQK
Protein: RHOMBOID-like protein 4 (AtRBL4) (EC 3.4.21.105) (F4JBM4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Rhomboid-like protein 11, chloroplastic
- Rhomboid-like protein 15
- Rhomboid-like protein 14, mitochondrial
- RHOMBOID-like protein 13
- Rhomboid-like protein 16, chloroplastic
- RHOMBOID-like protein 12, mitochondrial
- Rhomboid-related intramembrane serine protease family protein
- Rhomboid-like protein 17, chloroplastic
Sequence:
MGEKDSETAPIWGKTRERERSNNNNIQPMDLESSSSVSGQQRSLTQSRSSYEERGRGVKEFRSWFPWLIPCFVVANVAVFVITMYVNNCPKKSGDCFADFLGRFSFQNTRENPLLGPSSLTLQTMGGLDVKKVVKGDEGWRLLSCNWLHGGVVHLLMNMLTLLFIGIRMEREFGFIRIGLLYLISGFGGSILSALFLRSNISVGASGAVFGLLGGMLSEIFINWTIYSNKVVTIVTLVLIVAVNLGLGVLPGVDNFAHIGGFATGFLLGFVLLIRPHYGWINQRNGPGAKPHRFKIYQGILWTISLLILVAGFIVGLISLFNNVDGNEHCSWCHYLSCVPTSKWSCNREPASCTTTQLGNQLSMTCLRNGKSASYILANPSDSRINSLCVQLCR
Protein: NADPH:adrenodoxin oxidoreductase, mitochondrial (EC 1.18.1.6) (A0A0A0MTR6)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|PIRNR:PIRNR000362}.
Interaction partners:
Sequence:
MASRCWRWWGWSAWPRTRLPPAGSTPSFCHHFSTQEKTPQICVVGSGPAGFYTAQHLLKHPQAHVDIYEKQPVPFGLVRFGVAPDHPEVKTAHSGRCAFWGNVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLPENQELEPDLSCDTAVILGQGNVALDVARILLTPPEHLERTDITKAALGVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQLPGARPILDPVDFLGLQDKIKEVPRPRKRLTELLLRTATEKPGPAEAARQASASRAWGLRFFRSPQQVLPSPDGRRAAGVRLAVTRLEGVDEATRAVPTGDMEDLPCGLVLSSIGYKSRPVDPSVPFDSKLGVIPNVEGRVMDVPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDLKAGLLPSGPRPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLRLLGH
Protein: Protein COS4 (P43542)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein COS2
- Putative uncharacterized protein YLR379W
- Regulator of rDNA transcription protein 1
Sequence:
MKENELKNEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIYKSLAFRIWMLLWLPLSVWWKLSNNWIYPLMVSLLVLFWGPVFVLVIFRLSRKRSLSKQLTQFCKEITKSTPSSDPHDWEVVAANLNSYLYENKAWNIRYFFFNAMGCQEAFRTTLLEPFSLKKDEAAKVKSFKDSVPYIEEALGVYFREVEKQWKLFNSEKSWSPVGLEDAKLPKEAYRFKLTWFLKRISNIFMLIPFLNFLCCIYVSRGMCLLLRTLYLGWILFMLVQGFQNIRVLIMSMEHKMQFLSTIINEQESGANGWDEIARKMNRYLFEKKVWKNEEFFFDGIDCEWFFSHFFYRVLSAKKSMRALSLNVELWPYIKEAQLSCSEESLA
Protein: MUTator (O62011)
Organism: Caenorhabditis elegans
Interaction partners:
- RNA helicase
- MUTator
- RNA-directed RNA polymerase
- RNase NYN domain-containing protein
- PAP-associated domain-containing protein
- Exonuclease mut-7
- NFX1-type zinc finger-containing protein 1 homolog
- Piwi-like protein ergo-1
- SH2 domain-containing protein
- Zc3h12a-like Ribonuclease NYN domain-containing protein
Sequence:
MSESDDDYPELDISDQYIDPLGIVVGPPPASYTETDREETPMQNRTEDDTNSYGNSSGEHDYDSYLDSGDDDFDVDAYYANDNMDEPPPETIPDNLIQNVIGRNDNADYDFSDASNPEIMKRDLQLFLSSSLLSNPLKFRSGYSSDELDDCLKSCMGYSLQVTAVLLLPPEIISQLPNDSKTEHAHALVRGGWLQSKEGAFFPVISDSERETVVSLMNGSEEQHKRQERKKKEADTFESEEKEIRTLLTFNMIAELLMAVRNEYSIRSVKYQILSTAYTNMVTGAAHANIFRKYKDILQLDPEKLWNNDWFKEYTNRGTLKKFLTTARFSEIVVSQANGKTVELYFRADDEGNRPVVLFTDEHIADVRNKWKTGNQRNQNYGSQGNYRAGGQRSDDRRGPQQRRNVIVPDPNYQPSTFAGGISNNADDDGSLQPTTSSHFNRNTDRSTSRPPRAPTSPVNRVMETDPLMGQGTSSGAPQRSAIPNPFGGAPALSRSTITNGNRGPSYGDRGERVQDVGDTTSDSEITSEGSYSDEDPEQKEIKRQRRKDKLKKKQERELRSREKHTKSKQQPPSKIETRFNTYKKKSESSATDTSNTPPVDTVNVALPTPVVESSSTTAAPSIPVSTRPEVVVPPENPAPLREVGNFYSKSNHDEDRRNVQLPFTPADTHKPIKVAPKEPVRNPLLKERPSANGFINRRLPSHPAPPPVNQSQPANQPMQTAVYQNSHPGAPYIPQQPTYQPQLPVQQPQPHQYAPQPIHHQQPIHQPMHGQQYPPVNQQQPIYQQPAPQYPPYNSIQNNPQHGPSPFNYSQVPQPAYNHVGQQPSHMSNQPHINQNGYQNSYNPNQGPTSSDPNYGCNPQFNHYGSRSVYHEDHSSQRRRSPDQFPPNPPEYDPHGNFKLADYERDRMTVGYSQNPHQFDHHGSHMPHQSQPQGYDNFNGNSAPYFNKNGGQSNHQPEAQRSFSVLSSNRQPSNRELIFQDGIEKELRDIILRYRSMNLTVLTVQELRTEVSRRPAIPRYIDIVQYIRDSSSVAIVERGDIEPYVVLKDDIRN