wanglab/gogpt-training-data huggingface dataset:
Protein: Probable nitrate/nitrite transporter NarK2 (P9WJY7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Permits nitrate and nitrate transport into E.coli.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Nitrate reductase-like protein NarX
- Nitrate reductase-like protein NarX
- Nitrate reductase alpha subunit
- Probable respiratory nitrate reductase
- assimilatory sulfite reductase
- Probable nitrite extrusion protein 1 NarK1
- Probable respiratory nitrate reductase
- Nitrate/nitrite transporter
- Nitrite reductase small subunit
- Probable integral membrane nitrite extrusion protein NarK3
Sequence:
MRGQAANLVLATWISVVNFWAWNLIGPLSTSYARDMSLSSAEASLLVATPILVGALGRIVTGPLTDRFGGRAMLIAVTLASILPVLAVGVAATMGSYALLVFFGLFLGVAGTIFAVGIPFANNWYQPARRGFSTGVFGMGMVGTALSAFFTPRFVRWFGLFTTHAIVAAALASTAVVAMVVLRDAPYFRPNADPVLPRLKAAARLPVTWEMSFLYAIVFGGFVAFSNYLPTYITTIYGFSTVDAGARTAGFALAAVLARPVGGWLSDRIAPRHVVLASLAGTALLAFAAALQPPPEVWSAATFITLAVCLGVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFPPLVMGATYDPVDNDYTVGLLLLVATALVACTYTALHAREPVSEEASR
Protein: Twitchy (Q9VTN6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- 5'-3' exoribonuclease 2 homolog
- Uncharacterized protein
- LD38910p
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- Protein cutoff
- Decapping and exoribonuclease protein Rai1
- Hexosyltransferase
- Protein Cep89 homolog
Sequence:
MNFNDDPLAELLSDNSLDNDNFFETPAGVGHKKPAKLAKPKGKLEDLFGIQEETEADVQGQGTGARKTPNAISTPRIVKQKPSISLDDDLVEDDDLGFDPKRPKSGGTKRSLFDDLLTSNAEPKKNIFDEILAGDAVKRPATSKPSMSRQSTDTTTDNSQARPKTSTGRRSSAQSATINMNADPLGLFGRDTNATVSGMSTPVSKKRGTTADWLGLEQEPDQRPITPKAQTAKAQPSSESPSKNTADILRLPDSDENGMEQEAEMAAVPAPSVVTAATQNILMLSNLNLESNHKFNALQQQEAQLVIAAQMKSQERTLLEMQRRQEDQDRKFQALIQQQLQRQQQMEEHIKGQQERINMHLQLMMSQPVRVQDVVSTPPLVEKPEPEPERKEHHKATSQEQEHLLLLEMDAKRNLLEKQRLDELVANMKVNYEQEIEMIDSSYKKQIKVLEEHLSVVEKRLKDENSELRQYYIEKLEKQKEDYVEQISSLRQDHEDEVRKLRQSHELDLEGIRQAKMVELSAVQDHGNYLDTLRLASSNLQELRDGMSDNQERERQLEARERRLADQERRLKMDEETADDEKRRLMELVSTLELQLGRLSKESAEENWQLRQRMSSLEAERKAFEREKEFHREQMQRDEKRVEDLKALQLAEMERLHHDLQEERNQLTVERQQIELRQQLNEHGDPDRDRRELEAQLQVAREAIRRADEERDRYHKLQREMEQRKRHLLDKEHALNLKEDELGQATGAYRLATSRQHLAEQKAREADQLLQAKLKVMAKRAQEIAEKEAQLAHERMLVAQDRMALVNLKKQISRSRCAICKMGAESAEIAQRRANVNPTAATDLQLPQVTPSHAELLLKMSQEPGQVQSDIVDRMLDENIEASYRRMYNAPPSSSIDDPDYLLTLAGGLDDDSKVAMDHGLNVDEAFM
Protein: Dpr-interacting protein eta, isoform B (Dpr-interacting protein eta, isoform D) (Q9VMN9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Defective proboscis extension response 1, isoform A
- Defective proboscis extension response 4
- Defective proboscis extension response 3, isoform B
- Defective proboscis extension response 7, isoform F
- Defective proboscis extension response 2, isoform F
- Common Dpr-interacting protein
Sequence:
MQSNFCQCRKQTCALSVILLLILMSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQRIGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRERGEIVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIPPNAVNYVENFEARHKGKKRTKSSESHHPARAQEHSGEDMENPGKRKADLSLGAESIDSIYGNSAAGSRRRQDLGGVLLLLLPVAVAVAMSLATAGVMRETQMTLPPQTLTHV
Protein: Variant surface glycoprotein (VSG), putative (Q380Y2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MRSLLQIFLTVAASLVAGAAIQKAEAAAGQGIHEEDFNPLCAVSDELKKSEGYAKHLISELDAAASVGINQALRLKIYAETLSTATQRTKLRTLANAYIDYCIAEFTDTVNNCQTALGYTAATNYVAAGVDAVMDLLIGAEAGAAGANGACTRTGDATSSTAKTKSQLNAACTERYKADRPHNPAKKPTAANVRLAPRSGTALTSTNHQTCALTSTQSDCLFHSGHVNTRTIDFLDGLVGLKKDGLKTKAFDPSTAQEATHLALFTEKTALQTLNAIEGKAGAAAGNKSTEQLATLSTLASRAAASQEKKDSEGAELKTQEFGDAGSKINQALWHVVEKLEVAKEALPEASDRKLGSINSFQELTRVTGYYEALKDQQLEKLQKQLTELQETTKKKSKTREQICNEKKDADTCKADKNCKYDETKKEEPQCVLSDKGKQAAKEAESHAEKVGKTTIITGNNCFVIHKAPLLFAFLLL
Protein: Mitochondrial import receptor subunit TOM70 (Translocase of outer mitochondrial membrane 70 homolog A (Yeast)) (Q6PBY6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004572}.
Interaction partners:
Sequence:
MAASKPVEPQSGSGLPRWQLALLVGTPIVLGVGAVYLWNRSRAKEKQGKRNGERKTPEGSASPVQGQHGATNPELENLSPLDRAQSAKNKGNKYFKAGKYDHAIKCYTEAIGLCPKEKKGDLSTFYQNRAAAYEQQMKWTEVIQDCSQAVELNPRYVKALFRRAKALEKLDNKKECLEDVTAVCILEVFQNQQSMLLADKVLKQLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKKDEDKDKEGEASEVKGSSGYLKAKQYMEEENYDKIISECTKEIESGGRYSAEALLLRATFYLLIGNATAAQPDLDRVINMNDASVKLRANALIKRGSMYMQQQQPQLSTQDFNMAAEIDHRNADVYHHRGQLKILLDQVEEAVGDFDECIKLRPDSALAQAQKCFALYRQAYTGNNPSQVQKAMDGFEDVIRRFPKCAEGYALYAQALTDQQQFGKADEMYDKCIELEPDNATTYVHKGLLQLQWKQDLEMGLELISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIDMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVAKKYGLKPPTL
Protein: Leukocyte cell-derived chemotaxin-2 homolog (Chondromodulin II) (Q21241)
Organism: Caenorhabditis elegans
Function: Muscle-derived dendritic guidance cue, which is required for the formation of somatosensory dendritic arbors which extend from PVD and FLP sensory neurons during development. Ligand of a multi-protein dma-1 receptor-ligand complex, which is activated upon binding of lect-2, mnr-1 and sax-7 ligands to control the growth of dendrites that extend anteriorly from the PVD neuronal cell body. Enhances the binding of the mnr-1 and sax-7 ligands to the dma-1 receptor-ligand complex. Restricts the growth of secondary PVD dendritic branches and any irregularly positioned ectopic tertiary dendritic branches that originate from secondary branches, and promotes the formation of stable higher order dendritic branches. In particular, it is required for the formation of quaternary PVD dendritic branches and promotes their innervation of body wall muscles. Promotes self-avoidance of tertiary dendritic branches of PVD sensory neurons. Not required for the growth of dendrites that extend from AIY and PVQ interneurons, DVB GABergic neurons, PLM and ALM mechanosensory neurons, AFD sensory neurons and DD/VD and DA/DB motor neurons.
Subcellular location: Secreted {ECO:0000269|PubMed:27451901, ECO:0000269|PubMed:27705746}. Cell junction {ECO:0000269|PubMed:27451901}. Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:27451901}. Cell projection, dendrite {ECO:0000269|PubMed:27451901, ECO:0000269|PubMed:27705746}. Perikaryon {ECO:0000269|PubMed:27451901}. Cell surface {ECO:0000269|PubMed:27451901}. Note=Secreted by body wall muscles and taken up by coelomocytes (PubMed:27451901, PubMed:27705746). Localizes to the basement membrane of hypodermal tissues, body wall muscles and along fibrous organelles in larvae and adults (PubMed:27451901). Co-localizes with sax-7 at dendrites (PubMed:27451901, PubMed:27705746). Dendritic localization is dependent on sax-7, but not mnr-1 or dma-1 (PubMed:27451901, PubMed:27705746). {ECO:0000269|PubMed:27451901, ECO:0000269|PubMed:27705746}.
Interaction partners:
- Neuroglian
- Menorin
- Clc-like protein
- LRRCT domain-containing protein
- DH domain-containing protein
- Actin-4
Sequence:
MHLRTLHFLILIGIFIGGQTLGCMKKVCGNNAKNDFRRCPDTDGSCGNYHTERTSGEIIDGVDVRCHLGEPIYAPIEGEMYFWRPYGGKREKSCADQGVRIEGTGQWQGYAVHISSVKLSFFGGHVEAGDEIGEALNRYCFNDRGQNDVEPHVEIRLYKEGRLIDPTHHLQNCMCTGQICESNTRNVLLGDPFKTDKRYNGVRGWDVECQMIDDDDEDSPRAPMIYSPIAGEIVGRIRLFTDSNGAYTGCDNDGIFIVGIDDWLGFEARLYNVKARADIGFGRKRIIQGEPIATRLACENSPDSVFVEIRFEGRVVNITDIITAANCKTPNFPVF
Protein: A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein) (O75969)
Organism: Homo sapiens (Human)
Function: May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:O88987}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:O88987}. Note=Dorsal margin of the acrosomal segment. Ribs of the fibrous sheath in the principal piece of the sperm tail. {ECO:0000250|UniProtKB:O88987}.
Interaction partners:
- Ropporin-1A
- Calcium-binding tyrosine phosphorylation-regulated protein
- Sperm surface protein Sp17
- Ropporin-1-like protein
- Rhophilin-1
- A-kinase anchor protein 1, mitochondrial
- Outer dense fiber protein 1
Sequence:
MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKMDTSTDPVRVLSWLRRDLEKSTAEFQDVRFKPGESFGGETSNSGDPHKGFSVDYYNTTTKGTPERLHFEMTHKEIPCQGPRAQLGNGSSVDEVSFYANRLTNLVIAMARKEINEKIDGSENKCVYQSLYMGNEPTPTKSLSKIASELVNETVSACSRNAAPDKAPGSGDRVSGSSQSPPNLKYKSTLKIKESTKERQGPDDKPPSKKSFFYKEVFESRNGDYAREGGRFFPRERKRFRGQERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKIQVKDTTIATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSHGSQKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMKGMGDPKNRNVNFAMKSETKLREKMYSEPKSEEETCAKTLGEHIIKEGLTLWHKTQQKECKSLGFQHAAFEAPNTQRKPASDISFEYPEDIGNLSLPPYPPEKPENFMYDSDSWAEDLIVSALLLIQYHLAQGGRRDARSFVEAAGTTNFPANEPPVAPDESCLKSAPIVGDQEQAEKKDLRSVFFNFIRNLLSETIFKRDQSPEPKVPEQPVKEDRKLCERPLASSPPRLYEDDETPGALSGLTKMAVSQIDGHMSGQMVEHLMNSVMKLCVIIAKSCDASLAELGDDKSGDASRLTSAFPDSLYECLPAKGTGSAEAVLQNAYQAIHNEMRGTSGQPPEGCAAPTVIVSNHNLTDTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGCSVGEVLQSVLRYEKERQLNEAVGNVTPLQLLDWLMVNL
Protein: Phosphoinositide 3-kinase regulatory subunit 5 (D4A4I3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- phosphatidylinositol-4,5-bisphosphate 3-kinase
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
- Phosphatidylinositol 3-kinase regulatory subunit alpha
- Phosphatidylinositol 3-kinase regulatory subunit beta
- Phosphatidylinositol 3-kinase regulatory subunit gamma
- Guanine nucleotide-binding protein G
- RAC-alpha serine/threonine-protein kinase
Sequence:
MQPAATTCTEDRIQHALERCLHGLSLGRRSAPWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTQEVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLLLKAASTYHCFLTWPVPYCSICREMLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVADKLSTPGQSPHGAYTTLLLHAFQATFGTHCDLPKLHRKLQSKTLEELEDIFTETTEAQELASGIGDVAEARQWLRTKLQAVGEKAGFPGILDTASPGKLHTIPIPVARCYTYSWNQDSFDILQEVLLKEQELLQPGILGDDEEEEEEDLEIDRHIAERDSLLSTGSLVSHDSELLLTSSQASGPVLSRQVLTTFVSGLSDGMDSGYVEDSEESSSEWPKKPGSQQRQGHRRPRQKFNRFYKLLKSTSQLVLRRDSRSLECSPDPTLPLRRAGSLSSPLDFPTQLPSRAQRSRSLPQPKLSTQLPSWLLAPPSHHQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSKLRRLENSHPILTRFFKLQFFYVPVKRSHGASSSACLSSLNQASPLLPDSLKHPSPADLGKAPWEDSTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAESRPLEGSATQLPILADMLLYYCRFAARPVLLQVYQTELTFVTGEKTTEIFIQSLELGHSATTRAIKASGPGSKRLGIGDDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLSKACQKPEELDSSMEALTLTLTEVVKRQNPKSKKGFNQISTSYIKVDKVQIISSSSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSSLPPEGSLSQPAEAGSDLCSLLCLPIMTFSGALP
Protein: Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed] (P01040)
Organism: Homo sapiens (Human)
Function: This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21944047}.
Interaction partners:
- Cathepsin B
- Procathepsin L
- Pro-cathepsin H
- Cathepsin L2
- Solute carrier family 12 member 8
- Cathepsin S
- Protein-glutamine gamma-glutamyltransferase K
- Collagen alpha-5
- Desmoplakin
- Loricrin
Sequence:
MIPGGLSEAKPATPEIQEIVDKVKPQLEEKTNETYGKLEAVQYKTQVVAGTNYYIKVRAGDNKYMHLKVFKSLPGQNEDLVLTGYQVDKNKDDELTGF
Protein: Large ribosomal subunit protein uL13 (60S ribosomal protein L13a) (P35427)
Organism: Rattus norvegicus (Rat)
Function: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P40429}.
Interaction partners:
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein eL20
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein uL30
Sequence:
MAEGQVLVLDGRSHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLLRLRKQAEKNVEKKICKFTEVLKTNGLLV
Protein: Rifin (Q8IK34)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKVHYINILLFALPLNILEHNKNEPHTTPNHTQTTRSLCECKLYSPANYDSDPEMKRVMQQFEDRTTQRFHEYDEKMQSKRIQCKDRCDKEIQKIILKDKLEKQMVEQFSTLQTDIQSDSIPTCICEKSLEDKMEKECLKCAQNLGGIVAPSTGVLGEIAALAVNAWKTEAIKAAIAAAEKSGLAAGKVAGDIEGAAKVIELVKSTFKIEKLGFSTLESIINTNTYTNVTLISRSIHSEYIRSDCGNILSLSSRKNPICTSVEKQIVAKKVGNGVSPKDFIETIVEEVVEAADGVADTEAARVTATKTAAFEARNIAAVEATTTPYYTPIIVSIVAIVVIILIMVIIYLILRYRRKKKMKKKLQYIKLLKE
Protein: Keratin-associated protein 12-3 (High sulfur keratin-associated protein 12.3) (Keratin-associated protein 12.3) (P60328)
Organism: Homo sapiens (Human)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Interaction partners:
- Keratin-associated protein 10-8
Sequence:
MCHTSCSPACQPTCCIHSPCQASCYVPVSCQSSVCMPVSCTRIVCVAPSCQPSVCVPVSCRPIIYVTPSCQSSGCCQPPCTTALCRPISCSTPSCC
Protein: Secreted frizzled-related protein 1 (sFRP-1) (Q9R168)
Organism: Rattus norvegicus (Rat)
Function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Subcellular location: Secreted {ECO:0000250}. Note=Cell membrane or extracellular matrix-associated. Released by heparin-binding (By similarity). {ECO:0000250}.
Interaction partners:
- Protein Wnt
- Protein Wnt
- Protein Wnt-5a
- Protein Wnt
- Protein Wnt-4
- Frizzled-2
- Protein Wnt
- Tumor necrosis factor ligand superfamily member 11
- Protein Wnt
- Protein Wnt
Sequence:
VRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKKKELKRLVLFLKNGADCPCHQLDNLSHNFLIMGRKVKSQYLLTAIHKWDKKNKE
Protein: Uncharacterized protein, isoform H (Q9V9N5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFDQPPENELQKSHDHNPGALSEHQLRVQASLQRLNIPDWFRHYNKGPEKAADGENACTSATGGGYRPGNFTRKRAQESGRWQGLNSKTTSLSSLGSQRSDRSPLLMSPSAHSHHGGQSSYSCGSTTIHGPAPVQIGMGATRWSTSHLNSTQMSPGASQRGSFTRGAPINSSFISVASGSGLLRNSYRQPYLGWRSTEKLSQRTPHERLANSLLTQRTAPPSTRAGNETRTLHSVSTEIQSSIKEVTSAIVHFVNDQQQSQHPRSRSTSPNSRCWLESSFVGTRTLDSPQTPVIDNSPPELARKQQQLHPHQVHLDVGLSPVVSAGQLPHRMNGINRIGNGGACAASRQQLEVQSAAELQRLRRRSEGDAPTQEKHYSKEQSHKSNSHSVEAVDSAQPNNPKESRRASLGDPALAATRSDIGSGQLQLIEGPTTGFGSGQHVRCRNTKCDQSTSPSDAKKLYKSCHNCSHLYCSRECRRAHWEKHRKACLHSRASNICRQVLATCKDDIDSQRHLSLLARKGSLSQGRGVVRVLFRSAEAAEGFIKNGFQCMGEASYVRWPDLMPAEMGLELYSELLKLSTEYKPETKMLIYVAICVVSEAPGMGQAPVRWERQLVSRCAKLKLCKTVLAELEQHQAALLQPVSVVAVPERTEILILTFNPGQHSNRELILSNILDILSRRGVMLSKHYPEVFERLQTYSEGQSDKFNPVTLHPRDTQTGQNFVCIIMAVHTDNELTKLPSAADGGNRVTTIDVGSTSALVQLELGDDQICKTKSRES
Protein: CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99) (Q8TCZ2)
Organism: Homo sapiens (Human)
Function: Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}. Cell junction {ECO:0000250}. Secreted {ECO:0000269|PubMed:25326458}.
Interaction partners:
- CD99 antigen
- Paired immunoglobulin-like type 2 receptor alpha
- Paired immunoglobulin-like type 2 receptor beta
- Hematopoietic progenitor cell antigen CD34
- RNA-binding protein EWS
- Synaptophysin
- Gamma-enolase
- Platelet endothelial cell adhesion molecule
- Receptor-type tyrosine-protein phosphatase C
- Apoptosis regulator Bcl-2
Sequence:
MVAWRSAFLVCLAFSLATLVQRGSGDFDDFNLEDAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTTKRPVTTRAPANTLGNDFDLADALDDRNDRDDGRRKPIAGGGGFSDKDLEDIVGGGEYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEPQVKYSTLHTQSAEPPPPPEPARI
Protein: KICSTOR subunit 2 (J3KNH0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGESIPLAAPVPVEQAVLETFFSHLGIFSYDKAKDNVEKEREANKSAGGSWLSLLAALAHLAAAEKVYHSLTYLGQKLGGQSFFSRKDSIRTIYTSLHNELKKVVTGRGALGGTAPHVEELLSHLSEQLCFFVQARMEIADFYEKMYTLSTQKFINAEELVGLLDAIMKKYSSRFHHPILSPLESSFQLEVDVLCHLLKAQAQVSEWKFLPSLVNLHSAHTKLQTWGQIFEKQRETKKHLFGGQSQKAVQPPHLFLWLMKLKNMLLAKFSFYFHEALSRQTTASEMKTLTAKANPDFFGKISSFIRKYDAANVSLIFDNRGSESFQGHGYHHPHSYREAPKGVDQYPAVVSLPSDRPVMHWPNVIMIMTDRTSDLNSLEKVVHFYDDKVQSTYFLTRPEPHFTIVIIFESKKSERDSHFISFLNEVSLALKNPKVFASLKPGAKGSCYQCNYFVAFCLNYSKLLLQRK
Protein: Cyclin-dependent protein kinase-like (Protein kinase superfamily protein) (Q9LSM7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGCVLCKESTGDKRKHNNPDEPPPADLRNTEDLPSSSSTTTAAISVEIGEKKKKDLDSIQIQPERRTWHTGDFSAGSSRRPGMSLRTPEGWPPWLIAACGDSIKDLTPRRATTYEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLNHPNVIKLQGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSRVVTLWYRPPELLLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKKYRLPNATLFKPQHPYKRCVAEAFNGFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTEPLPCDPSSLPKYPPSKELNVKLRDEELRRQKGLAGKGSGIDGARRIRYRGDRTGRAIPAPEANAESQANLDRWRSISQTNGKSKSEKFPPPHQDGAVGYPLEDLSKKTSVFGAKTETSFGLSRSLKSGEGTSMRKISNKDGARGASSRKYIWGLKPPPALGLSMDLLFRSRSEVFGIRR
Protein: ACT domain-containing protein ACR4 (Protein ACT DOMAIN REPEATS 4) (Q8LJW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May bind amino acids.
Interaction partners:
Sequence:
MSFSQDMDNEYEKLIRRMNPPRVVIDNDSCKKATVIRVDSANEYGILLEVVQILTDLNLTITKAYISSDGGWFMDVFNVTDQDGNKVTDEVVLDYIQKSLGPEACFSTSMRSVGVIPSTDSTVIELTGCDRPGLLSELSAVLTHLKCSVLNAEIWTHNTRAAAVMQVTDDLTGCGISDPERLSRIKNLLRNVLKGSNTPREAKTVVSHGEVHTDRRLHQMMFEDRDYEHRLVDDDSSIQDERQRPDVCVDNWLDKDYSVVTVRCKDRPKLLFDTVCTLTDMQYVVFHGSVDTEGTEAFQEYYVRHIDGSPVKSEAEKQRVIQCLEAAIKRRVSEGLKLELCTTDRVGLLSNVTRIFRENSLTVTRAEVKTKGGKALNTFYVSDASGYSIDAKTIDSIRQTIGQTILKVKNNPQEQQQRQKSPSHESPTRFLFGGLFKSKSFVNFGLVRSYS
Protein: ASCIZ zinc finger protein, isoform A (ASCIZ zinc finger protein, isoform B) (AT25633p) (Q9VZU1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Dynein light chain 1, cytoplasmic
- RH23915p
- LD29420p
- LD24318p
- Serine/threonine-protein kinase ATM
- Brickwall, isoform A
Sequence:
MHSEKHTPDIRELMPVREHRCERCPSLVFGNLSHYQLHLRRRHQEVIPPSVIGPIVAFHCPVEKCIYHVATKGARSFTSLRLLRQHYQKSHLDKNYKCLACGGKFLLQHHLEKHQCSKHKCPVCELTYNSKAGLRTHMRRKNHLVHHESDKVPIPSLATWKRLNPQPIPVSADSLTAHSLKTGSDLHPSEEYINNLPSNLAGVTELYAEIPNPEANMPSTLELDTNLPAAEEHILCFLPIMDVSYALEMSSQKLDMETQTEEDDLNEIRNEVLAPLLRDIETQTPDTRGDIGTMTDDFPEEQEPVAVGSHFHAYSETEPMFDLQTSAHMYTQTCDDLFEELGLSHIQTQTHWPDGLYNTQHTQTCDEIMDELFPDNFQSTCTQTRWLD
Protein: Wilms tumor protein 1-interacting protein homolog (WT1-interacting protein homolog) (xWtip) (A9LS46)
Organism: Xenopus laevis (African clawed frog)
Function: May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Acts as a transcriptional corepressor for snai1 and snai2/slug and plays a role in regulating neural crest development. Involved in the organization of the basal body. Involved in cilia growth and positioning.
Subcellular location: Cell junction, adherens junction {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MEKYDEDIALQASKFLEDLSLCDGHSRLYGPVGDMLLSNDHILVADHRGRRLNGSLTQYLPHSSSDKVYPLGSSQLRSMNGSRGDGYMDEGIYKSDVALPCYSGISEKNKRYSAELYRHSCGNSFEGVPISAKQGGITALYSGGKMSNSCMSATSPRSSMASSASSSQEHSKYSSPRSSISSNALSLDKFSSPRSSLVVPGQQEKYTSPRSSLGQYEGGVLSPRSSYASTTSDTSKHSSPRASLTSYDCGSKPSSNRTSGISMGYDQRHISPRSSTASQYSCTTSPRSSYSDSRYVPSGNPDLDGVGGHGSLVSPRSSMCLQEGRSATLGSCNPSVVSPRSSISSHSSRSSRSSRGSMGAYTDLTVPSPRSSMLGTSLQEETLVQDLGEACHYKVLTQSPPRQEQHQTITSSHDLNSGAVASYNFSSAKGSATVHRFKLPYQVTPSRESGPSQAERRLEALTLELEKELELHMKKEYFGICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECYHCEDCQLQLNDEEGRRCYPLEGHLLCHSCHIRRLSVNVPPHQPPSYPMHVTEL
Protein: Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate) (Q9UGK3)
Organism: Homo sapiens (Human)
Function: Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10980601}.
Interaction partners:
- Protein-tyrosine kinase 6
- Signal transducer and activator of transcription 3
- Macrophage colony-stimulating factor 1 receptor
- Epidermal growth factor receptor
- Myeloid differentiation primary response protein MyD88
- Leptin receptor
Sequence:
MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH