wanglab/gogpt-training-data huggingface dataset:
Protein: P-loop containing nucleoside triphosphate hydrolases superfamily protein (F4I5A3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004572}.
Interaction partners:
- Alba DNA/RNA-binding protein
- Defensin-like protein 4
- Inositol oxygenase 5
- Transducin/WD40 repeat-like superfamily protein
- Putative pectate lyase 11
- Transcription factor DUO1
- Protein DMP9
- TLC domain-containing protein At5g14285
Sequence:
MDSKQMLLSALGVGVGVGVGLGLASGQAVGKWAGGNSSSNNAVTADKMEKEILRQVVDGRESKITFDEFPYYLSEQTRVLLTSAAYVHLKHFDASKYTRNLSPASRAILLSGPAELYQQMLAKALAHFFDAKLLLLDVNDFALKIQSKYGSGNTESSSFKRSPSESALEQLSGLFSSFSILPQREESKAGGTLRRQSSGVDIKSSSMEGSSNPPKLRRNSSAAANISNLASSSNQVSAPLKRSSSWSFDEKLLVQSLYKVLAYVSKANPIVLYLRDVENFLFRSQRTYNLFQKLLQKLSGPVLILGSRIVDLSSEDAQEIDEKLSAVFPYNIDIRPPEDETHLVSWKSQLERDMNMIQTQDNRNHIMEVLSENDLICDDLESISFEDTKVLSNYIEEIVVSALSYHLMNNKDPEYRNGKLVISSISLSHGFSLFREGKAGGREKLKQKTKEESSKEVKAESIKPETKTESVTTVSSKEEPEKEAKAEKVTPKAPEVAPDNEFEKRIRPEVIPAEEINVTFKDIGALDEIKESLQELVMLPLRRPDLFTGGLLKPCRGILLFGPPGTGKTMLAKAIAKEAGASFINVSMSTITSKWFGEDEKNVRALFTLASKVSPTIIFVDEVDSMLGQRTRVGEHEAMRKIKNEFMSHWDGLMTKPGERILVLAATNRPFDLDEAIIRRFERRIMVGLPAVENREKILRTLLAKEKVDENLDYKELAMMTEGYTGSDLKNLCTTAAYRPVRELIQQERIKDTEKKKQREPTKAGEEDEGKEERVITLRPLNRQDFKEAKNQVAASFAAEGAGMGELKQWNELYGEGGSRKKEQLTYFL
Protein: Lupus La protein homolog (La autoantigen homolog) (La ribonucleoprotein) (P32067)
Organism: Mus musculus (Mouse)
Function: Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- RNA-binding protein Ro60
- Heterogeneous nuclear ribonucleoproteins C1/C2
- Nucleolin
- Heterogeneous nuclear ribonucleoprotein K
- ELAV-like protein 1
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Zinc finger CCCH domain-containing protein 15
- Peptidyl-prolyl cis-trans isomerase G
- Serine/arginine-rich splicing factor 3
- Heterogeneous nuclear ribonucleoprotein L
Sequence:
MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRRRGPMKRGRDGRDREEPASKHKKRENGARDK
Protein: ATP-dependent protease subunit ClpQ (EC 3.4.25.2) (Q8I5B6)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- ATP-dependent Clp protease proteolytic subunit
- ATP-dependent Clp protease proteolytic subunit
- Heptatricopeptide repeat-containing protein
- riboflavin kinase
- ATP-dependent zinc metalloprotease FTSH 1
Sequence:
MFIRNFVNIIGSQKSITKTIARNYFSDNSKLIIPRHGTTILCVRKNNEVCLIGDGMVSQGTMIVKGNAKKIRRLKDNILMGFAGATADCFTLLDKFETKIDEYPNQLLRSCVELAKLWRTDRYLRHLEAVLIVADKDILLEVTGNGDVLEPSGNVLGTGSGGPYAMAAARALYDVENLSAKDIAYKAMNIAADMCCHTNNNFICETL
Protein: At1g56580/F25P12_18 (F25P12.97 protein) (Q9FXB0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein kinase superfamily protein
- Protein OCTOPUS-like
- AT3g07470/F21O3_18
- Glutaminyl-peptide cyclotransferase
- GDSL esterase/lipase At5g14450
- Homeobox-leucine zipper protein HDG2
Sequence:
MGLVTDEVRARAEKYTGDEICREKTKEFLKEVSMPNGLLPLKDIEEVGYDRETGIVWLKQKKSITHKFEAIGKLVSYATEVIAQVEVGKIKKLTGVKAKELLIWVTLNELVLEQPTSSGKINFRTPTGLSRTFPVSAFVVPEVEKPATEKNNGTTEVKEAVAVTDA
Protein: ABC-type glycine betaine transport system substrate-binding domain-containing protein (Q9HTI6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable permease of ABC transporter
- Probable ATP-binding component of ABC transporter
- Probable permease of ABC transporter
- Quaternary amine transport ATP-binding protein
- Probable glycine betaine-binding protein
- Electron transfer flavoprotein alpha/beta-subunit N-terminal domain-containing protein
- Lipoprotein-releasing ABC transporter permease subunit
- Glycine betaine monooxygenase oxygenase subunit
- ABC-type glycine betaine transport system substrate-binding domain-containing protein
- Quaternary amine transport ATP-binding protein
Sequence:
MKGCKSWLLAVSLCAPLAAQAAEPESCASVRFADVGWTDITVTTAVTRQVLESLGYKTKVNLLSVPVTYRSLANNDLDVFLGNWMPTMTNDIKQYAEKGTVETLRANLEGAKYTLAVPQYVYDGGLRSFADIAKFSDKLGNKIYGIEPGNDGNRVAQSMIDKNAFELGKFKLVESSEAGMLSQVQRAIRRNQWVVFLGWEPHPMNTRFQMKYLEGGDDFFGPNYGGATIYTNVRKGYAQECANVGQLLKNLSFTLEMENKLMDAVLNENKKPEEAAKAWLKDHPEQLDAWLAGVTTRDGQPAAAAAKLAFAK
Protein: CRAL-TRIO domain-containing protein (Guanine nucleotide exchange factor UNC-73B) (Q7KPP4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGDYDGKMTMKAEDILHVLRDGIAVLPGGRCRAGQAVIVCPSREQPVNQDNLRNVFLYLFEVTSKMAREKGFLVVIDMRGKQTWTNVRHILKALSSIESSSTVQVFIIKPEKFWEKQKAQMSLGTWDFEVEMISFESLIKIIDSSHLPKTVGGSYPYDHDEWLELRLDLEKWIWNITEIMEKLESVRREICEGEQPVDVTTANAALKKSQHAKNSIFNVPVEGIETEGNKIATRILKPSKGVKNPDLEATTPYISNLTDSLRLLKGEVAKNWEVRQMELSKVYQQKQFERDAEHMIETLRPYKKACERSMGDVGGCANDVVRLSAEFEQFQIAVRGMEVSVKQVFDKENHLRTIGARNQITDHVAARLAEEWHLVKELMERRSAVLHNAKEFFTSAQRYFAEVPRWTAQPGVNPNDVLFNQESLEEAIRKHDAFWAQVEEVYAQAYDDASKVTRALKEADAEDNVAREHSSRLQRAHKQLMEKWKERQVLLHHMLAMIAFETDVRLVVDWLEQHGEPYLRRNIHIGENVNQARSFQRNHTNFQRVAANTYGNVQKLHQVYQDVTKSGSKICDVDTMHGLMTDLSAKIEKFTKIENSRELLLRQSVLFHTHYKELTDWYGKMGEKYKDRRIDLTVPTCDKNKERFVLETDETAQAYAMTIDEGKTLIEMMQRATRVFDVDYSASVAHIQLLISDIEDKNTQISSEWSPRRTLLHIASKFAMFEQNQFEVLEQIKSWEVDMREMAESDSFYDKADSVLPFHKDNQQQVRNAIADIQKSAKELSQALYSQKLTDLRDKRDRVVLEAIREHVRELEIAESRVMTYANETSMRMQAASEVGDLRRISNSVCKLIDNQLSALTQLGVIPNDYNDTVQKQEELRAFRDAVQHKLKEPYDAFVIRFRELMENRLANRDEVVYHNEAIQAKYCRLMNLCEDRNKLLKSAHGCYKTYETAVLPILNQLESEYHSPTVTDWCAGCTSSIDADRAAYVADLLSKHMDYKERFGKGCTYALRNGDFLLRYIRRSTVNQSERKRHETKIADMKNNIRERQSNILELWMQKKLLLEGCQSFIFIEASAKELLEFMKGEGNRKLKHFEKKGRRESTDDDDEFAKFKSEVKQKKTDIQTFLMLSTNETMSRGVHGDEIDRCIEQVKDEFSRFSRRVGDCEVVLRGENGSTQSSKDEFSLDRHSDTAIFNEKKINERREENRKMLEPMRELIQSERDYIKDLERCVNIYVKEFDQAAKNGTIPTLNPLKYEIFGNIEKIFKFHNDKLLHELIKYENQPEAVGASFIVWIDLLNELYTEYCVNKEQKNHVIATPDAVSFFTGIRERHGLEINNEIASLLIKPVQRITRYRLLIEQLMRSCTDKTNDLKEAYEVVCSVPRKVNDLIHYNCLDLKDFKVDELGPFVTQDTLTFWEPRAYFKGRGKERQVFLFDISIVFAKRIEVSPKNIKYVIKGKPLPLSEVSIVEHVEGDTCRFGLRVGTVSSNDNRIDLKANNHHTKVKWVQKIRDLTAGMLPLGLGVSEAYSVGTLSTARSVSVRSGASTSSGGENRQSQDVESLLRHRYSVHSCDSEQSSEVWIVTADFDGQVEGHLTVHKGDRVEIVEDQATDCAEYVQVVLCDQPTKHGLVPASIIAPQNSE
Protein: Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-) (Q8CBY0)
Organism: Mus musculus (Mouse)
Function: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03149}.
Interaction partners:
- Glutamyl-tRNA
- Glutamyl-tRNA
- Glutamine--tRNA ligase
- Asparaginyl-tRNA synthetase
- Asparagine--tRNA ligase, cytoplasmic
Sequence:
MWSRAASVRFRAPLDAGRSFASKANPQGKVQAAGLGTQAPRLVPQGSGRVSPAVIEHLERLALVNFGSREAVDRLEKAIAFADQLHAVDTDGVEPLESVLEDRCLYLRSDNVAEGSCAEELLQNSNHVVEEYFVAPPGNISLPDMVNKIPSSTAE
Protein: Solute carrier family 25 protein Shawn (Solute carrier family 25 member 39 homolog) (Q9VWG0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Mitochondrial transporter required for glutathione import into mitochondria.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:26865615}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MATREACGQFAAASAAMAAASSQNPSKATMTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGVVEPTFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYNIDQHNRSNQATKGPGS
Protein: Eukaryotic translation initiation factor 4B2 (AtTif4B2) (eIF4B2) (Protein SPONTANEOUS NECROTIC SPOTS) (Q9SAD7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes the eIF4F and eIF4A RNA-dependent ATP-hydrolysis activity with different efficiency depending on mRNAs, thus providing mRNA discrimination during initiation of translation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- F14J8.16 protein
- F3F19.7
- Oxidoreductase/transition metal ion-binding protein
- Large ribosomal subunit protein uL5m
- Pentatricopeptide repeat-containing protein At1g13040
- Eukaryotic translation initiation factor isoform 4G-2
- Probable mediator of RNA polymerase II transcription subunit 19b
- Pentatricopeptide repeat-containing protein At1g12300
- Large ribosomal subunit protein P3y
- Large ribosomal subunit protein P3z
Sequence:
MSKPWGGIGAWADEAERADEEQAAEATATAADSQSFPSLKEAATAKSSKKKKKMTLSEFTKGAYTAPSSAGLTREQMLQLPTGPRQRSEDEMQPGRLGGGFSSYGGGRSSGPPGRMSRDREDSDGSWGGGGGGRRSYGGFDDDQRGSNSRVSDFPQVSRADEDDDWGKGKKSLPSFDQGRQGSRYGGGGGSFGGGGGGGAGSYGGGGAGAGSGGGGGFSKADEVDNWAAGKAKSSTFGSGFRESGPEPDRWARGVLPSGGGVQEERRRLVFEPRKADTEVSETPTAVKTSKPSPFGAARPREQVLAEKGLDWKKLDSDIEAKKGQTSRPSSAQSSRPSSAQSNRSESSALNNVENVVKPRPKVNPFGDAKPREVLLEEQGKDWRKIDSELEHRRVDRPETEGERMLKEEIEELRKKLEKEAAIAPESKESQQESDSNHQNLPDLIREKEKNLDLLIRELDDKVRFRPRAVERPGSSASRGGSYSERPHSRAGSIDESRSVESMERPRSHGTGDNWPRPVDDRRNFQGSKERGFFNNRNFDRSSSAREGW
Protein: Protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) (Transglutaminase protein A) (TGase A) (Q9HZX3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Displays transglutaminase activity (TGase) in vitro. Plays a critical role in the viability of P.aeruginosa. Might contribute to an essential function linked to the cell wall.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:23209712}; Multi-pass membrane protein {ECO:0000269|PubMed:23209712}.
Interaction partners:
- Uncharacterized protein
- CHAD domain-containing protein
- AAA family ATPase
- Methyltransferase domain-containing protein
- Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal domain-containing protein
- Type IV pilus inner membrane component PilN
- Type IV pilus inner membrane component PilP
- LysM domain-containing protein
- Type 4 fimbrial biogenesis protein PilZ
- Type IV pilus inner membrane component PilO
Sequence:
MNAIPRVALVWLLVAQVLVILPHLAYMPLWIAAMWLGCAAWRVQVFRMRAGYPRAWVKLALALLAGAGVWLSRGSLVGLDAGAVLLIAAFILKLVEMKTRRDALVLVFLGFFAVVVGYLFDDGFLAALYSLLPVTALLAALIGLQQSAFASRPWPTLRLAGGLLLQALPLMLLLFLFFPRLGPLWSLPMPGNKGVTGLSESMAPGDIAELGRSAELAFRVRFEGALPPREQLYWRALTMERFDGRRWAQAPQWSGEDALHWQKRGPELRYDVIMQPSSQPWLFALDVAQTDQTDTRLMSDFHLQRRQPVEQRLFYRVSSWPQALRESSIDPRTRWRNLQLPMHGNPRARALADELRQAHAQPQALVAALLQRFNHEPFAYTLKPPATGADGVDDFLFDTRSGFCAHYAGAMAFVLRAAGIPARVVAGYQGGELNPAGNYLLVHQFDAHAWVEYWQPEQGWLSVDPTYQVAPERIEQGLEQALAGDSEYLADAPLSPLRYRGLPWLNDMRLAWDSLNYGWQRWVLAYQGEQQGAFLQRWFGGLDPTRLGLLLGAAAILSVGLLALFLLKPWQGRGDLRSRQLRRFERLLEMHGLRRSPGEGLRSYGERAARVLPAQAPAIAAFVGAFEAQRYGHGGADDPGLRLRALRRALPWRLVRTPTRDGRGEEQA
Protein: UV excision repair protein RAD23 (Q8IMB7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU367049}. Cytoplasm {ECO:0000256|RuleBase:RU367049}.
Interaction partners:
Sequence:
MLTRDSSSSNRNQLSVKESNKLTSTDDSKQSMPCEEANHTNSPSSTNTEDSVLSRETRPLSSDELIGELAQASLQSRAESNLLMGDEYNQTVLSMVEMGYPREQVERAMAASYNNPERAVEYLINGIPAEEGTFYNRLNESTNPSLIPSGPQPASATSAERSTESNSDPFEFLRSQPQFLQMRSLIYQNPHLLHAVLQQIGQTNPALLQLISENQDAFLNMLNQPIDRESESGATVPPVSNARIPSTLDNVDLFSPDLEVATSAQRSAAGTSAAHQSGSAADNEDLEQPLGVSTIRLNRQDKDAIERLKALGFPEALVLQAYFACEKNEEQAANFLLSSSFDD
Protein: Small ribosomal subunit protein eS19 (40S ribosomal protein S19) (Q6PBW7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MPGGVTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDENWFYIRAASTVRHLYLRGGVGVGSMTKIYGGRKRNGVCPSHFSVGSKNVARKVLQALEGLKMVEKDPNGGRRLTPQGTRDLDRIAGQVAAASKKV
Protein: Serine protease 1 (EC 3.4.21.4) (Anionic trypsin I) (Anionic trypsin-1) (Beta-trypsin) (Cationic trypsinogen) (Pretrypsinogen I) (Trypsin I) (Trypsin-1) (P00762)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Chymotrypsinogen B
- Proteinase-activated receptor 1
- Serine protease inhibitor Kazal-type 1
- Proteinase-activated receptor 2
- Serine protease inhibitor Kazal-type 1-like
Sequence:
MSALLILALVGAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGDEQFINAAKIIKHPNYSSWTLNNDIMLIKLSSPVKLNARVAPVALPSACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAYPGEITSSMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALPDNPGVYTKVCNFVGWIQDTIAAN
Protein: Lymphocyte antigen 75 (Ly-75) (DEC-205) (CD antigen CD205) (Q60767)
Organism: Mus musculus (Mouse)
Function: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B lymphocytes (By similarity).
Subcellular location: Membrane {ECO:0000269|PubMed:7553896}; Single-pass type I membrane protein {ECO:0000269|PubMed:7553896}.
Interaction partners:
- CD302 antigen
- C-type lectin domain family 9 member A
- C-type lectin domain family 4 member K
- Integrin alpha-X
- Leukocyte elastase inhibitor
- NK13
- R86
- Leukocyte elastase inhibitor B
- Leukocyte elastase inhibitor A
- Leukocyte elastase inhibitor C
Sequence:
MRTGRVTPGLAAGLLLLLLRSFGLVEPSESSGNDPFTIVHENTGKCIQPLSDWVVAQDCSGTNNMLWKWVSQHRLFHLESQKCLGLDITKATDNLRMFSCDSTVMLWWKCEHHSLYTAAQYRLALKDGYAVANTNTSDVWKKGGSEENLCAQPYHEIYTRDGNSYGRPCEFPFLIGETWYHDCIHDEDHSGPWCATTLSYEYDQKWGICLLPESGCEGNWEKNEQIGSCYQFNNQEILSWKEAYVSCQNQGADLLSIHSAAELAYITGKEDIARLVWLGLNQLYSARGWEWSDFRPLKFLNWDPGTPVAPVIGGSSCARMDTESGLWQSVSCESQQPYVCKKPLNNTLELPDVWTYTDTHCHVGWLPNNGFCYLLANESSSWDAAHLKCKAFGADLISMHSLADVEVVVTKLHNGDVKKEIWTGLKNTNSPALFQWSDGTEVTLTYWNENEPSVPFNKTPNCVSYLGKLGQWKVQSCEKKLRYVCKKKGEITKDAESDKLCPPDEGWKRHGETCYKIYEKEAPFGTNCNLTITSRFEQEFLNYMMKNYDKSLRKYFWTGLRDPDSRGEYSWAVAQGVKQAVTFSNWNFLEPASPGGCVAMSTGKTLGKWEVKNCRSFRALSICKKVSEPQEPEEAAPKPDDPCPEGWHTFPSSLSCYKVFHIERIVRKRNWEEAERFCQALGAHLPSFSRREEIKDFVHLLKDQFSGQRWLWIGLNKRSPDLQGSWQWSDRTPVSAVMMEPEFQQDFDIRDCAAIKVLDVPWRRVWHLYEDKDYAYWKPFACDAKLEWVCQIPKGSTPQMPDWYNPERTGIHGPPVIIEGSEYWFVADPHLNYEEAVLYCASNHSFLATITSFTGLKAIKNKLANISGEEQKWWVKTSENPIDRYFLGSRRRLWHHFPMTFGDECLHMSAKTWLVDLSKRADCNAKLPFICERYNVSSLEKYSPDPAAKVQCTEKWIPFQNKCFLKVNSGPVTFSQASGICHSYGGTLPSVLSRGEQDFIISLLPEMEASLWIGLRWTAYERINRWTDNRELTYSNFHPLLVGRRLSIPTNFFDDESHFHCALILNLKKSPLTGTWNFTSCSERHSLSLCQKYSETEDGQPWENTSKTVKYLNNLYKIISKPLTWHGALKECMKEKMRLVSITDPYQQAFLAVQATLRNSSFWIGLSSQDDELNFGWSDGKRLQFSNWAGSNEQLDDCVILDTDGFWKTADCDDNQPGAICYYPGNETEEEVRALDTAKCPSPVQSTPWIPFQNSCYNFMITNNRHKTVTPEEVQSTCEKLHSKAHSLSIRNEEENTFVVEQLLYFNYIASWVMLGITYENNSLMWFDKTALSYTHWRTGRPTVKNGKFLAGLSTDGFWDIQSFNVIEETLHFYQHSISACKIEMVDYEDKHNGTLPQFIPYKDGVYSVIQKKVTWYEALNACSQSGGELASVHNPNGKLFLEDIVNRDGFPLWVGLSSHDGSESSFEWSDGRAFDYVPWQSLQSPGDCVVLYPKGIWRREKCLSVKDGAICYKPTKDKKLIFHVKSSKCPVAKRDGPQWVQYGGHCYASDQVLHSFSEAKQVCQELDHSATVVTIADENENKFVSRLMRENYNITMRVWLGLSQHSLDQSWSWLDGLDVTFVKWENKTKDGDGKCSILIASNETWRKVHCSRGYARAVCKIPLSPDYTGIAILFAVLCLLGLISLAIWFLLQRSHIRWTGFSSVRYEHGTNEDEVMLPSFHD
Protein: Tau-cadinol synthase (EC 4.2.3.173) (Terpene synthase 7) (ZmTPS7) (Q5GJ59)
Organism: Zea mays (Maize)
Function: Sesquiterpene synthase that catalyzes the formation of a blend of sesquiterpenes and sesquiterpenoid alcohols. Converts farnesyl diphosphate to tau-cadinol.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q6Q3H2}.
Interaction partners:
Sequence:
MATTGTTSMPAPVFHPTVWGDYFIKFVPEPLQVSDETMAERIRHLREEVSGMFQACKNVVDKTNLVDVVQRLGIDHHFEEQIATALASIHSAGLFNSSSLHEAALRFRLLRQQGFWVPADELVKFIKNEDGSFIDGITNDPKGLLSLYNAAHLVTHDEGTTTLEDAIAFARQHLEAARRCSLKSPLAEQVGRALGIPLPRTLKREEAIAFIPEYSSQQDQQVYSPVILELAKLDFNLLQHLHQEELKEISQWWKDLSGEIGLGYVRDRIVECYFWSYTVHYERGQARARMILAKVFMLTSLLDDTYDVHATLEEARELNKAIQRWDESDVSLLPEYLKKFFVKVISNFREFEDELESHEKYRNVYNIKGFQTLSKHYLQEAEWFHHGCTPSFKDQVNVSVITGGAQVLSIGLLVGMGHEATREAFEWAIGDTDAIWACGEVSRFMDDMSAFKNGRNKMDVASSVECYIKEHNVPSEVALARINSLVEDAWKTINQAPFKYPALFPVVQRVTSLAKSMTLLFLDKRDAYTYSKDFQTTLETHFVRHIPL
Protein: Fatty acid hydroxylase domain-containing protein (G8B7T4)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Fatty acid hydroxylase domain-containing protein
- Delta
- Fatty acid hydroxylase domain-containing protein
- Squalene synthase
- C-22 sterol desaturase ERG5
- Sterol 24-C-methyltransferase
- C-8 sterol isomerase
- 3-keto-steroid reductase ERG27
- Terpene cyclase/mutase family member
- Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating
Sequence:
MDIVLEVCDYYLFDRLYAAALPKGGKVDQFIQNSPVFQQVSSKISQFLPSSSCSGCSDTVDNALFGNTTASSTFSNALNFQFNATSVNVANLPSYLWSKVMSLQNKSEIYGLKPTFLPAGDYFSSSILARSNLLRESLTILVITTIFGWLLYLIVAYLSYVFVFDRRIFNHPRYLKNQMWLEIERAMTAIPVMVALTNPFFLLELKGFSRLYFDINECTGGWKFVFLQIPMFILFTDCLIYCIHRWLHWPSVYKRLHKPHHKWIVCTPFASHAFHPVDGWAQSLPYHLYPLLFPLHKVLYLGLFTFVNFWTVMIHDGNYMSNDPVVNGTACHTVHHLYFNYNYGQFTTLWDRIGRSYRRPDDSFFIKETTAEKEKQEWKKQVTQMEEIRNELEGKVDDREYAEES
Protein: Vacuole membrane protein hfl11 (Q09906)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:30451685}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Autophagy-related protein 8
- CUE domain-containing protein 5
- Probable cysteine protease atg4
- SUMO-conjugating enzyme ubc9
Sequence:
MDNEIVALCGFFVAIALVLSCISIITHLKNYKKPVLQRSVVRILMMIVIYSSVSFLSVYNEKIGSIFEPFREIYEAFALYCFFCLLIDYLGGERAAVISLHGHLPRPRLWPLNYLQDDIDLSDPYTFLSIKRGILQYTWLKPFLVIAVLLTKVTGVYDREDQPVYASADLWIGLVYNISITLSLYSLTTFWVCLHEELAPFRPFPKFLSVKAIIFASYWQQTVLSITNWLGLLNGTGWIYSLLNQNVLMCLEMPFFALSHWYAFRIEDYDTPTWLSCARLPLLKAFKDVIGLKDVWCDSLQTLHGDRYVYQNFEPGENLIPSRNDGRINRTSHGLRYSQGGQSKYWISRYDQSRVRLINNSQNSPQSNKSYFSIPGMSTSHFENGLQFEIDDEMEPLYNQAKQMRYGDYNYPVLLVNNTHASSSYT
Protein: E3 ubiquitin-protein ligase RNF135 (EC 2.3.2.27) (RING finger protein 135) (RING-type E3 ubiquitin transferase RNF135) (Q9CWS1)
Organism: Mus musculus (Mouse)
Function: E2-dependent E3 ubiquitin-protein ligase that functions as a RIGI coreceptor in the sensing of viral RNAs in cell cytoplasm and the activation of the antiviral innate immune response. Together with the UBE2D3, UBE2N and UB2V1 E2 ligases, catalyzes the 'Lys-63'-linked polyubiquitination of RIGI oligomerized on viral RNAs, an essential step in the activation of the RIG-I signaling pathway. Through a ubiquitin-independent parallel mechanism, which consists in bridging RIGI filaments forming on longer viral RNAs, further activates the RIG-I signaling pathway. This second mechanism that synergizes with the ubiquitin-dependent one would thereby allow an RNA length-dependent regulation of the RIG-I signaling pathway. Associated with the E2 ligase UBE2N, also constitutively synthesizes unanchored 'Lys-63'-linked polyubiquitin chains that may also activate the RIG-I signaling pathway (By similarity). It is not involved in the innate immune response against DNA viruses.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:28469175}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q8IUD6}.
Interaction partners:
- Antiviral innate immune response receptor RIG-I
- Interferon-induced helicase C domain-containing protein 1
- Mitochondrial antiviral-signaling protein
- Ubiquitin-conjugating enzyme E2 N
- ATP-dependent RNA helicase DHX58
- RNA-binding E3 ubiquitin-protein ligase MEX3C
Sequence:
MAAVCSGNAVPVWLSEDDLSCIICQGLLDQPTTLPCGHSFCLRCLHDLWVSKRGAVDGCPWACPICRKGPLTKPKLHKNPLLQDLVDKYLQAAREVEAGSEPEPAPAPRSAPQVTVQKSTTNVIQELTDMVRQLVDDVKSLQTQRPNLGSGQDNAQGTPPTDSSSEGEHSLDSPKLVTFSISQKKIQEILHNLEEIQEKLQGSVPGRAPPRERVQEMTSSLCLLPDQRRPAPRKASHLSLWAISPTFDLRTLSYNLEVSNNSRRVTVSRGDLHTYHWSPQRFSISQVFCSQALSSGQKYWEVDTRNCSHWAIGVASWGMKRDGMLGRTMDSWCIEWRGPGQFSAWAKMKKTDLQSDLPEVVGVWLDLESGELAFYAVADHERLLYECEVSSSSPLHPAFWLYGLSPGNYLEIKQLNT
Protein: Viking, isoform A (Viking, isoform B) (Viking, isoform C) (Q9VMV5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
Interaction partners:
- Nidogen
- Collagen alpha-1
- Pericardin
- Integrin beta-PS
- Integrin beta-nu
- Laminin subunit alpha
- BM-40
- Laminin subunit gamma-1
- Protein decapentaplegic
- Peroxidasin
Sequence:
MLPRDLRHLSGLLGVVYLLGSLVSVTLADGKICNTTLCDCKGIKGRMGAPGPIGVPGLEGPAGDIGPPGRAGPLGEKGDVGEYGEQGEKGHRGDIGPKGEMGYPGIMGKSGEPGTPGPRGIDGCDGRPGMQGPSGAPGQNGVRGPPGKPGQQGPPGEAGEGGINSKGTKGNRGETGQPGGVGPPGFDGDRGSKGDTGYAGLTGEKGDPGLPGPKGDTGAVSELPYSLIGPPGAKGEPGDSLSGVLKPDDTLKGYKGYVGLQGDEGPQGPTGEQGAVGRNGLPGARGEIGGPGERGKPGKDGEPGRFGDKGMKGAPGWTGADGLDGSPGERGEDGFTGMPGVQGGAGPPGIYDPSLTKSLPGPIGSQGDIGPPGEQGPPGLPGKPGRRGPIGLAGQSGDPGLNGSRGPPGRSERGEAGDYGFIGPPGPQGPPGEAGLPGRYGLHGEPGQNVVGPKGEPGLNGQPGLEGYRGDRGEVGLPGDKGLPGEGYNIVGPPGSQGPPGFRGLPGDDGYNGLRGLPGEKGLRGDDCPVCNAGPRGPRGQEGDTGYPGSHGNRGAIGLTGPRGVQGLQGNPGRAGHKGLPGPAGIPGEPGKVGAAGPDGKAIEVGSLRKGEIGDTGDSGHRGDTGDDGEKGRDGSDGSKGERGETGQRGDYGDAGYQGRDGEPGRDGRDGAPGRNATTPKVYLIGEPGYDGIKGERGDDGDTGFKGVKGEPNPGQIYDNTGEPGEDGYTGPKGVKGAKGEQGAIGLRGEIGDRGPAGEVIPGPVGAKGYPGPTGDYGQQGAPGLPGRDGEPGLDGGIGYKGQRGVPGQEVIQGEIGPPGRSGIKGFPGDVGAPGQYGLAGRPGPKGVKGEQGPDGAVGQTGLPGNKGQRGDFLVGPPGPKGQPGRNGRQAPHGAKGQKGEVGSLGQNGQNGAKGSIGFSGRRGLLGNAGLQGLPGSPGIPGLPGMIGEIGERGEIGYNGRQGDIGPRGPNGEFGPKGLSGDDGPDGYPGANGLPGRKGETGNPGFPGRPGAKGVAAYSGIKGDDGESGLTGPIGYPGAPGAKGQRGPVGDSQPALDGVAGRKGEVGSPGPNGLPGRHGLKGQRGDRGLPGQQGRPGEPGAKGLGGYPGRNGINGLKGATGFPGPQGPKGPQGESGVVGLDGRNGQIGDQGPRGLIGEQGEQGEQGDEGEVGIPGRLENLRDRSFYRGFTGDQGLQGERGEQGDMGPIGFIGPPGAKGERGDIGYAGQLGFDGAEGLKGFQGDQGPRGPPGITLPAEKGDEGVAGLDGRAGRPGHFGQKGAPGPPGENGPNGAIGHRGPQIQGPPGPQGDVGFPGAPGHNGRHGLIGPKGELGDMGRQGERGESGYAIVGRQGDIGDIGFQGEPGWDGAKGEQGYPGLPGKNGRVGAPGPRGPTGDAGWGGIDGMDGLVGPKGQPGVTYSYSMARPGDRGEPGLDGFQGEEGDGGAPGLIGFQGQRGAVGYRGDQGEVGYTGADGPQGQRGDKGYMGLTGAPGLRGLPGPQGEPAPAPPAPKSRGFIFARHSQSVHVPQCPANTNLLWEGYSLSGNVAASRAVGQDLGQSGSCMMRFTTMPYMLCDITNVCHFAQNNDDSLWLSTAEPMPMTMTPIQGRDLMKYISRCVVCETTTRIIALHSQSMSIPDCPGGWEEMWTGYSYFMSTLDNVGGVGQNLVSPGSCLEEFRAQPVIECHGHGRCNYYDALASFWLTVIEEQDQFVQPRQQTLKADFTSKISRCTVCRRRGNSFVARTAKSRADASSGFTDGSASSNPSGSLKTDGNYRANWQSGRSSSPGSQSSPGSSSGSWSSGSNAGAYPGSNAGAYSGSNAGAYPGSNAGAYPGSNAAWQSRTNAGSSWHSGPVAGSVSNPGSYSSWSTGSSPGSNPESNAGSTRSSWITRSRGPSNYLNGRYQQRVHPSNLQAYDEYARHGGNTRQYNRRPREDTTAP
Protein: Rho-associated protein kinase (EC 2.7.11.1) (Q961D4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MPAGRETVTKQRSMDVERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIPEKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKGFDGNHLPFIGFTYTGDYQLLSSDTVDAESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEALLERERGRSEALEQQDAGLRQQIELITKREAELQRIASEYEKDLALRQHNYKVAMQKVEQEIELRKKTEALLVETQRNLENEQKTRARDLNINDKVVSLEKQLLEMEQSYKTETENTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQKHKEELGQENAELQALVVQEKNLRPQLKEMHKEAENKMQTLINDIERTMCREQKAQEDNRALLEKISDLEKAHAGLDFELKAAQGRYQQEVKAHQETEKSRLVSREEANLQEVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLEGECRQESEKVAALQSQLDQEHSKRNALLSELSLHSSEVAHLRSRENQLQKELSTQREAKRRFEEDLTQLKSTHHEALANNRELQAQLEAEQCFSRLYKTQANENREESAERLSKIEDLEEERVSLKHQVQVAVARADSEALARSIAEETVADLEKEKTIKELELKDFVMKHRNEINAKEAALATLKEAENELHKKLGQKAAEYEDLVQQHKKQQEELALMRSSKDEEITKLLDKCKNEVLLKQVAVNKLAEVMNRRDSDLPKQKNKARSTAELRKKEKEMRRLQQELSQERDKFNQLLLKHQDLQQLCAEEQQLKQKMVMEIDCKATEIENLQSKLNETASLSSADNDPEDSQHSSLLSLTQDSVFEGWLSVPNKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLYAGEGASHRPDEQSQLDVSVLHGNCNEERPGTIVHKGHEFVHITYHMPTACEVCPKPLWHMFKPPAAYECKRCRNKIHKEHVDKHDPLAPCKLNHDPRSARDMLLLAATPEDQSLWVARLLKRIQKSGYKAASYNNNSTDGSKISPSQSTRSSYKPYAVNVQRSATLPANSSLK