wanglab/gogpt-training-data huggingface dataset:
Protein: Heterogeneous nuclear ribonucleoprotein U like 1 (M0R3F1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ
Protein: Ig delta chain C region membrane-bound form (P01882)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
DKKEPDMFLLSECKAPEENEKINLGCLVIGSQPLKISWEPKKSSIVEHVFPSEMRNGNYTMVLQVTVLASELNLNHTCTINKPKRKEKPFKFPESWDSQSSKRVTPTLQAKNHSTEATKAITTKKDIEGAMAPSNLTVNILTTSTHPEMSSWLLCEVSGFFPENIHLMWLGVHSKMKSTNFVTANPTAQPGGTFQTWSVLRLPVALSSSLDTYTCVVEHEASKTKLNASKSLAISGIVNTIQHSCIMDEQSDSYMDLEEENGLWPTMCTFVALFLLTLLYSGFVTFIKVK
Protein: Gamma-terpinene synthase 1 (EC 4.2.3.114) (Alpha-terpinene synthase 1) (EC 4.2.3.115) (Terpene synthase 1) (TvTPS1) (A0A0M3Q1Q3)
Organism: Thymus vulgaris (Thyme)
Function: Involved in the biosynthesis of phenolic monoterpenes natural products thymol and carvacrol which have a broad range of biological activities acting as antimicrobial compounds, insecticides, antioxidants and pharmaceutical agents. Monoterpene synthase which catalyzes the conversion of geranyl diphosphate (GPP) to gamma-terpinene and the minor products alpha-thujene, alpha-terpinene, myrcene, sabinene, (+)-R-limonene, alpha-pinene and alpha-phellandrene.
Interaction partners:
Sequence:
MRRSGNYQAPVWNNDFIQSFSTDKYKDEKFLKKKEELIAQVKVLLNTKMEAVKQLELIEDLRNLGLTYYFEDEFKKILTSIYNEHKGFKNEQVGDLYFTSLAFRLLRLHGFDVSEDVFNFFKNEDGSDFKASLGENTKDVLELYEASFLIRVGEVTLEQARVFSTKILEKKVEEGIKDEKLLAWIQHSLALPLHWRIQRLEARWFLDAYKARKDMNPIIYELGKIDFHIIQETQLQEVQEVSQWWTNTNLAEKLPFVRDRIVECYFWALGLFEPHEYGYQRKMAAIIITFVTIIDDVYDVYDTLDELQLFTDAIRKWDVESISTLPYYMQVCYLAVFTYASELAYDILKDQGFNSISYLQRSWLSLVEGFFQEAKWYYAGYTPTLAEYLENAKVSISSPTIISQVYFTLPNSTERTVVENVFGYHNILYLSGMILRLADDLGTTQFELKRGDVQKAIQCYMNDNNATEEEGTEHVKYLLREAWQEMNSAMADPDCPLSEDLVFAAANLGRTSQFIYLDGDGHGVQHSEIHNQMGGLIFEPYV
Protein: Probable indole-3-acetic acid-amido synthetase GH3.6 (EC 6.3.2.-) (Auxin-responsive GH3-like protein 6) (OsGH3-6) (Q60EY1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May catalyze the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin.
Interaction partners:
Sequence:
MAATAWGIRSSGIRGASPVMSACVSPAEVILGADHQQQMYCHLLCGLRRWDAVDCIRAPYAAALARALRLLQSKWRQLCDDLECGTVCADVVTDAAMRGAVQDGVLAGPCPELAGRVRRICERDDWRGVLRQLWPDARYISCVTTGTMEQYFPAIKHFAGEALPVLGTDYLASECAIGINLERTSPPEETTYVLLPRAAYFEFIPFDMDAAGRGAAAAEPVDIAGVEAGKTYELVATTFRGLYRYKVGDVVKIAGFHHSSPRLQFVTRAPPPQEHGEVLTERDVMAAMDTFQLMLKDGGEVIEFAAFIIDGDGGQRRRRCATIAVEVSNGSKLLDHERSAAFLRRCTAPLEGCLGGAYRLSRATGDVAPLEVAVVRPGTFDRLAEAAIRGGAPANQYKPPRSSGTGTSSMCCNPPWCAAAAQSLNQLLTSICLIVSLNQRQFLDRESNSGTDKVFISDSILNFQHWGGFSLRFDLQEESLTLYKDHPS
Protein: Geranylgeranyl diphosphate synthase (Q24K59)
Organism: Paracoccus haeundaensis
Interaction partners:
Sequence:
MRRDVNPIHATLLQTRLEEIAQGFGAVSQPLGAAMSHGALSSGRRFRGMLMLLAAEASGGVCDTIVDAACAVEMVHAASLIFDDLPCMDDAGLRRGRPATHVAHGESRAVLGGIALITEAMALLAGARGASGTVRAQLVRILSRSLGPQGLCAGQDLDLHAAKNGAGVEQEQDLKTGVLFIAGLEMLAVIKEFDAEEQTQMIDFGRQLGRVFQSYDDLLDVVGDQAALGKDTGRDAAAPGPRRGLLAVSDLQNVSRHYEASRAQLDAMLRSKRLQAPEIAALLERVLPYAARA
Protein: Homeobox protein siamois (Q91848)
Organism: Xenopus laevis (African clawed frog)
Function: Essential for Wnt/beta-catenin-mediated formation of the Spemann organizer and for induction of the organizer precursor, the Nieuwkoop center. Acts as a transcriptional activator, cooperating with TGFbeta signals to induce a program of organizer-specific gene expression and to generate an organizer with both head- and trunk-inducing activity. Activates the head organizer gene cer1 by acting synergistically with otx2 and mix-A/mix.1 through the 5'-TAATCT-3' element of the cer1 promoter. Also binds as a complex with lhx1/lim1 and mix-A/mix.1 to the 3x 5'-TAAT-3' element of the cer1 promoter. Required for subsequent dorsoventral axis formation in the embryo, dorsalizing ventral mesoderm and cooperating with t/bra to induce dorsal mesoderm. Also involved in neural induction, inducing the cement gland and neural tissue in overlying ectoderm. Later in development, has the second function of indirectly repressing ventral genes, probably by activating the expression of a transcriptional repressor.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MTYEAEMEQIVSTALTLQDDYIKFTPRNQNMACHAEIIGIFHDIHPTVEIKEPHQDKSVLQETLVELYSVLGIPQEPQVSKTMKFEEPEQHKESSSTVTRSDSLVNSLQSTGLKRPFCEDEHREYKKPLIQAEDISPATSTRSRKRTIYSKEQTNFLQNQFDLNPYPDFVNRCRIAKITGIPEPRIQVWFQNRRARHLPRATTFHSPQGRKSPTSEGPRSFLSREAHYPDEWGQAPNPSNTQPYPN
Protein: T cell receptor beta constant 1 (P01850)
Organism: Homo sapiens (Human)
Function: Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation. The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity.
Subcellular location: Cell membrane {ECO:0000303|PubMed:20452950}.
Interaction partners:
Sequence:
DLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFPDHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSVSYQQGVLSATILYEILLGKATLYAVLVSALVLMAMVKRKDF
Protein: Thymidine kinase, cytosolic (EC 2.7.1.21) (P27158)
Organism: Rattus norvegicus (Rat)
Function: Cell-cycle-regulated enzyme of importance in nucleotide metabolism. Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate. Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration.
Subcellular location: Cytoplasm.
Interaction partners:
- Thymidylate synthase
- Thymidine phosphorylase
- Thymidine kinase 2, mitochondrial
- dTMP kinase
- Deoxycytidylate deaminase
- Cytidine deaminase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- Uridine phosphorylase
- Uridine phosphorylase
- UMP-CMP kinase
Sequence:
MSYINLPTVLPISPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLKDVAQEALGVAVIGIDEGQFFPDIVDFCETMANTGKTVIV
Protein: Transcription initiation factor TFIID subunit 13 (TBP-associated factor 13) (O60076)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- SAGA complex/transcription factor TFIID complex subunit Taf6
- Transcription initiation factor TFIID subunit 2
- SAGA complex/transcription factor TFIID complex subunit Taf12
- SAGA complex/transcription factor TFIID complex subunit Taf10
- Transcription initiation factor TFIID subunit 11
- SAGA complex/transcription factor TFIID complex subunit Taf9
- Transcription initiation factor TFIID subunit 7
- Transcription initiation factor TFIID subunit 4
- Transcription initiation factor TFIID subunit 8
- TATA-box-binding protein
Sequence:
MSMENRRGRPPTRRQHLFTKDLKSLMYAFGDDVNPAPDSINVLEEIVVDYINEMCLEAARIAGNRNKVKVDDFKFALRDDPKKLGRVEELLVLQKMIADTRNVMKYNKDHF
Protein: L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59) (P00338)
Organism: Homo sapiens (Human)
Function: Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
Subcellular location: Cytoplasm.
Interaction partners:
- Pyruvate kinase PKM
- Pyruvate kinase PKLR
- L-lactate dehydrogenase C chain
- NAD-dependent malic enzyme, mitochondrial
- Pyruvate carboxylase, mitochondrial
- Glucose-6-phosphate isomerase
- Fructose-bisphosphate aldolase A
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase, mitochondrial
- Putative aspartate aminotransferase, cytoplasmic 2
Sequence:
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
Protein: Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (M9T5Z6)
Organism: Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei)
Interaction partners:
Sequence:
MPLFCRYYSQKYPEMDDVVMVTVRSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSMNKLIRVGKTEPVVVIRVDKEKGYIDLSKRRVSKEDVERCTEKFAKAKAVNSIIRHVGELLGYTSEEQVEELYQKTAWHFEEKFKKQAYAYDVFKQAVIDPTILDECNLDEETRTVLLSQIQRKLQSQAVKIRADIEVSCFEYEGIDAVKSSLREGIAQSTQEIPIRINLIAPPLYVMTTQTTEKQDGLRALESAITEVTSKITSYGGTLSVKMAPKIVTDVEETDLARQLEKAEEENREVGGDDDDEEEVGMGELDVDSEEEEEKDSEDKKDDE
Protein: Small ribosomal subunit protein uS10 (40S ribosomal protein S20) (O74893)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein eS27
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS3
Sequence:
MSQVAKDQKEQQIPSTVHRIRITLTSRNVRNLEKVCSDLVNRAKDKQLRVKGPVRLPTKILKITTRKTPNGEGSKTWETYEMRIHKRLIDLHSPSEIVKQITSIHIEPGVEVEVTIAQ
Protein: Glycogen phosphorylase, liver form (EC 2.4.1.1) (P09811)
Organism: Rattus norvegicus (Rat)
Function: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P06737}.
Interaction partners:
- Glycogen debranching enzyme
- 1,4-alpha-glucan branching enzyme
- Phosphoglucomutase-1
- Pancreatic alpha-amylase
- Alpha-amylase.
- UTP--glucose-1-phosphate uridylyltransferase
- Receptor-interacting serine/threonine-protein kinase 3
- Phosphoglucomutase 2-like 1
- Glycogen phosphorylase, brain form
- Glycogen phosphorylase, muscle form
Sequence:
MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAGTKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVGDDIFLREIAKVKQENKLKFSQFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEAYVKCQEKVSQLYMNQKAWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKESSNGVNANGK
Protein: GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (A0A1W2PNQ8)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367138}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367138}.
Interaction partners:
Sequence:
MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLRLCGKPKSHFM
Protein: Xylanase inhibitor protein 2 (Class III chitinase homolog h) (Q53NL5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Fungal xylanase inhibitor. Possesses competitive inhibiting activity against several fungal endo-1,4-beta-D-xylanases belonging to glycoside hydrolase family 10 (GH10) and family 11 (GH11). May function in plant defense against secreted fungal pathogen xylanases. Is similar to class III chitinases, but does not exhibit chitinase activity.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MGLVHALLPFAAAAALLLLAAPPPATADDPGLAVYWGRHKEEGSLREACDTGRYTTVIITFYNAFGHGRYSLDISGHPLAAVGADIKHCQSRGITVLLSIGGQGGAYSLPTNASAADVADNLWNAYLGGHRAGVARPFGDDAAVDGIDFFIDQGGADHYDDLARRLDGYNKYYRGRVGVLLTATTRCSYPDHRLEKALATGVFARIHVRMFGDEQCTMSPRYSWEKWAAAFPGSKVYIGLVASPEQDSAWMFQKDLYYEMLQFVRSLPNYGGLAIYDRYFDKKANYTGEG
Protein: Adaptor related protein complex 1 subunit mu 3 (LOC570897 protein) (A9JT98)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
Sequence:
MAASAIFILDLKGKVLICRNYMGNIDMNVIDNFMPIMMKREEEAELSPVVIHGSTHFLWIKHSNLYLVAMTKKNTNAALVYSFLYKLVEVFTEYFKSLEEESIRDNFVTVYELMDEVMDFGFPQTTDSKILLEYITQQGHKLEVGAPRPPATVTNAVSWRSEGIKYRKNEVFMDVIESVNLLVSATGSVLRSEILGCIKLKVVLSGMPELRLGLNDKVLFEITGREKTKSVELEDVKFHQCVRLSRFENDRTISFIPPDGESELMSYRLNTTVKPLIWIESVIEKFSHSRVEIKVKARSQFKSRSTANNVSILVPVPSDADSPKFKTTTGQAKWVPEKSAVEWNIKSFPGGKEFMMRAHFGLPSVESDELEGKRPITVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYTTQSGDYQLRTN
Protein: Dual specificity phosphatase ibp1 (EC 3.1.3.48) (Cdc25-like phosphatase ibp1) (Itsy bitsy phosphatase 1) (Q8WZK3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May play a role in DNA replication checkpoint via regulation of hsk1 or may act downstream of hsk1 in an S phase regulatory pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Meiotically up-regulated gene 153 protein
Sequence:
MSTLSYVSPDALKGWLMESPNEISIIDVRDYDYEGERIPGSVRIPSDTFLASVDQHVDDLMKKRSLIVHCTYSQVRGPKAARVLSEILRNRITESKEKLSLSQKEKLFQNLPTVYILHGGFSAWKRRYGGQQGLIEYD
Protein: OspR (Q9I018)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Glutathione peroxidase
- Organic hydroperoxide resistance protein
- OxyR
Sequence:
MSTRGKVARPDGVEESLLLDNQLCFKLYAASRAVIRGYRPLLEQIGLTYPQYLVMLVLWEWHASPPEQPTVKALGDRLLLDSGTLTPLLKRLEQLGLVDRRRASHDEREVHLTLTVPGITLRERVIPLRQQLICSTGFDLNEMFDLHQRLGGLLSRFRLVVGG
Protein: Probable TonB-dependent receptor (Q9HVC0)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell outer membrane {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}.
Interaction partners:
- Second ferric pyoverdine receptor FpvB
- Insulin-cleaving metalloproteinase outer membrane protein
- VreA
Sequence:
MPRSIPLRPAPLALSLSLFASFSAPALAADPVEQQMVVIGSRAPTSISELPGTVWVIEREQLDQQTQAGVPLKEALGQLIPGLDIGSQGRTNNGQNLRGRSVLVMIDGVSLNSSRGISRQFDSIDPFNIERIEVMSGASAVYGGGATGGIINIVTKKGVGGDTRFNTELGARSGFQSHEDHDLRAAQSISGGNDLFNGRLAIAYQKNGAAYDGSGDQVLTDITQTDLQYNRSVDLMGSLGFTFANGHSLDLGLQYYDSGYDGDRGLDLGRNFDALRGRAPYSIKGGVDLDREPESKRHQFNATYHAPEVLGHDLYLQAYYRNEKMAFNPFPTIRYSNTGAINYGTSYYSASQQDTDYYGMKLALVKTWERASLTYGVDLDREKFTSDQMLFNLPLAAASGGLVASEQAKLGRYPDIDTDSRAFFLQGSWKATDDLTLSAGVRRQSMSTDVSDFVAANQQILIANGLGKTADAVPGGSKDYDVNLVNVGAIYKLNLQQQVWANYSEGFELPDPAKYYGFGRYGAADGNGHYPLLQGVSVNDSPLDGIKTKQVELGWRHTDGALDTQVAAFYSWSDKSIKYDSKTLAVLQQDTKKRNYGLEGQATYWLDDHWQVGVNGLAIRSQEKVDGRWLKQDVTSASPSKAGAFVGWKDDQRSLRLQGVRTFNLNDEPGNKIDGYALFDLLGTQALPVGTLTAGIQNLLDKDYTTVWGQRAQVYYGGLAPAGLFDYKGRGRTYSLTYSVEF
Protein: Type-1 angiotensin II receptor B (AT3) (Angiotensin II type-1 receptor B) (AT1 receptor B) (P29089)
Organism: Rattus norvegicus (Rat)
Function: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P30556}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P30556}.
Interaction partners:
- Angiotensinogen
- Guanine nucleotide-binding protein G
- Type-2 angiotensin II receptor
- Plasminogen activator inhibitor 1
- Type-1 angiotensin II receptor A
- Guanine nucleotide-binding protein subunit alpha-12
- Guanine nucleotide-binding protein subunit alpha-11
- Prothrombin
- Guanine nucleotide-binding protein subunit alpha-13
- Angiotensin-converting enzyme 2
Sequence:
MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
Protein: Chelated iron transport system membrane protein YfeC (Q56954)
Organism: Yersinia pestis
Function: Part of an ATP-driven transport system YfeABC for chelated iron.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Iron-binding protein YfeA
- Chelated iron transport system membrane protein YfeB
- Chelated iron transport system membrane protein YfeD
- Zinc import ATP-binding protein ZnuC
- High-affinity zinc uptake system protein ZnuA
- Divalent metal cation transporter MntH
Sequence:
MLELLLQPFNYNYMVKAIWVSAIVGAVCAFLSAYLMLKGWSLMGDALSHSVVPGVAGAYALGFPYAAGAFFTGMLAALAMTLVRHITRLREDAIIGFIFSTFFAVGLLIVSLNPTSVNVQSIIFGNILGIADEDVLQVEIIILVSFVILCLIWKDLLAVFFDESHAMSIGLSPLRLKILFFTLLSACTVAALQTVGAILVIAMVVTPGATAYLLTDRFGRLLIIAIAIGAITSAFGAYLSFYLDGATGGVIVTLQTLVFLPAFFFAPKHGLLATRYRTRLKRRHPPVHLPEDNL
Protein: Cell division control protein 15 (Q09822)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Cell division control protein 12
- Ingression protein fic1
- Anillin-related medial ring protein mid1
- Ras GTPase-activating-like protein rng2
- LIM domain-containing protein C4F6.12
- Myosin type-2 heavy chain 1
- Myosin regulatory light chain cdc4
- cytokinesis protein 3
- Myosin regulatory light chain 1
- 1,3-beta-glucan synthase component bgs1
Sequence:
MEVNGVSQSEAAPYVTKSSVKFRDNFWGSEDAGMDALMSRTKSSLSVLESIDEFYAKRASIEREYASKLQELAASSADIPEVGSTLNNILSMRTETGSMAKAHEEVSQQINTELRNKIREYIDQTEQQKVVAANAIEELYQKKTALEIDLSEKKDAYEYSCNKLNSYMRQTKKMTGRELDKYNLKIRQAALAVKKMDAEYRETNELLLTVTREWIDRWTEVCDAFQHIEEYRLEFLKTNMWAYANIISTACVKDDESCEKIRLTLENTNIDEDITQMIQNEGTGTTIPPLPEFNDYFKENGLNYDIDQLISKAPSYPYSSSRPSASASLASSPTRSAFRPKTSETVSSEVVSSPPTSPLHSPVKPVSNEQVEQVTEVELSIPVPSIQEAESQKPVLTGSSMRRPSVTSPTFEVAARPLTSMDVRSSHNAETEVQAIPAATDISPEVKEGKNSENAITKDNDDIILSSQLQPTATGSRSSRLSFSRHGHGSQTSLGSIKRKSIMERMGRPTSPFMGSSFSNMGSRSTSPTKEGFASNQHATGASVQSDELEDIDPRANVVLNVGPNMLSVGEAPVESTSKEEDKDVPDPIANAMAELSSSMRRRQSTSVDDEAPVSLSKTSSSTRLNGLGYHSRNTSIASDIDGVPKKSTLGAPPAAHTSAQMQRMSNSFASQTKQVFGEQRTENSARESLRHSRSNMSRSPSPMLSRRSSTLRPSFERSASSLSVRQSDVVSPAPSTRARGQSVSGQQRPSSSMSLYGEYNKSQPQLSMQRSVSPNPLGPNRRSSSVLQSQKSTSSNTSNRNNGGYSGSRPSSEMGHRYGSMSGRSMRQVSQRSTSRARSPEPTNRNSVQSKNVDPRATFTAEGEPILGYVIALYDYQAQIPEEISFQKGDTLMVLRTQEDGWWDGEIINVPNSKRGLFPSNFVQTV
Protein: Protein YrdA (P0A9W9)
Organism: Escherichia coli (strain K12)
Interaction partners:
Sequence:
MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAGLRYSANNYVKWKDEYLDQGNQTQP