wanglab/gogpt-training-data huggingface dataset:
Protein: Contig An02c0090, genomic contig (A2QCD2)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Interaction partners:
Sequence:
MPTISSAHLDQDSPPPSHLLYSQSPPSVDPIPVSTSPVETRPRTASAPSLQHNSAPSAVVAPSQPATTTTTTTATNNSTGFTGSVIGSISRRNRRSFAALAREKTSNALANLSSIGAPNYPLRSSASSGSLSKHSRKASQVSVSEAPGATPLTPPLSDGSASSERSSPAPFDAATSRSSPAVVEQQTSSVERRRYTLQRAPSPLEQLPEVGPTVSPAKMHQTSSRLLRMTEDDRPFTKDFMDLFSTLMVSLKLDSHRVRFTKYDHSFTSEEAINNLGSLKFSQSNRMPDPKDPSRIVTTTTTTTFSMAKEMARSVCQRFVDARFIEAVDGKSAQIFPLKGALYQLTPKGINILQRFCQRNGITARHVIDVLESPRNTMQLVNLERDTDTDKLSHDRATIEVIFRRFAGQDGPNVKSSISTSDSDSLSDYSNGLVGVKMAKERKINDKIVINTFTGKAAVDWLMDCSTTIERRETVLIAELFVKYGLITMLQEDRFINQPDDSIVAFQPSKNAIYGITDRGQRVCGWIARDKSRETTMYDNRGIPKDSNNARLNHILHDPALRLLFREFLRFSLCEENLSFYLDVSEFTSAYHKAEKLGTFRKPDAVRETLAAAYGLYNAFLAPGSPCELNIDHALRNSLASRMTKAVGDDESMLKSLQEVVHLFEMAQTSVFKLMSSDSVPKFLRDPKCASILQEHDVDLIGAPRAYSPTPAPVPERSASRSARS
Protein: Cytoplasmic 60S subunit biogenesis factor SPCC550.15c (pre-60S factor REI1 homolog) (O59811)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Pre-60S-associated factor involved in the cytoplasmic maturation of the 60S subunit. Involved in the dissociation and recycling of other late pre-60S factors before newly synthesized large ribosomal subunits enter translation (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Eukaryotic translation initiation factor 6
- 60S ribosomal export protein nmd3
- Ribosome biogenesis protein rlp24
- Probable metalloprotease arx1
- Ribosome assembly factor mrt4
- Large subunit GTPase 1
- Ribosome biogenesis protein nsa2
- Ribosome biogenesis protein ytm1
- Nucleolar GTP-binding protein 2
- Probable nucleolar GTP-binding protein 1
Sequence:
MSTSFACTTCTVAFNNAESQKIHWKSDWHHYNLKRKVASLPPLSAEVFAGKILSIQKQNEEVQKKAEFYQNCEVCNKKFYSEGAYSSHMASKKHRDNLSKFQRNSRIKKLQSEDASSIASSTLSMGEPVVDSEIEEEEDLASQLTSRAISLSNLSLHGRESEPSKTELATSIPQSNEASKSHLFTQEPTPEEIEAELARRSSQRLSPRDCLFCAASFSSFDTCKKHMKASHSLYIPEREYLVDEPSLFDYLAEKISIGFTCLTCNREFKSLEAVRAHMQQKGHTSIAYDTEDEQLELSDFYDFTTSYPDYAVKQDETVVEEDGSSGEGDWEDVSDDSDNSSLDSLEMGRVPIADEYELHLPSGNRVGHRSLSRYFRQNLHSSSTAVGDGASIHQNVARRAMSGNARAYRQAVETSIAGVRDGRKNYSASHIKSFQDQRRREEFANKMGIKNNTKKHFRDALLQ
Protein: Mangetout, isoform D (B7YZT0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MTTANIVAAPAAPTISPAITSTATRIGGKAVPTPRLLGSGAANVAQILAKSLDSPSPSSSSGWPVKHAAVLEGDVILGGLMMVHSREDSITCGPIMPQGGIQALEAMLYTLDQVNKQQLLPNVTLGAHLLDDCDKDTYGLEMAVDFIKAHIQINSEYITVKTEAKAKMKTFCDESKWSVQICLLLLLVVLSTCHILQTESQVVGDIEQADDGVASSHRRSRSHSASHQAHVGNGNNPGCKHLHHRQHRGKSHARKHRQSHYEMLELEQRQQRMGKHWRQWMSHLQSPDYANDDPLPDGRRSSPANADLTYDHFELEDYQRYANIDLASPRSGRHRGRHLPLNNMNLMLPLSSADGSGKYLRSLPDSVSFQNDRLYATQPQRHWPVKREAIVEGDVILGGLMMVHSREDSITCGPIMPQGGIQALEAMLFTIDRINREQLLPNITLGAHILDDCDKDSYGLEMAVDFIKGSISNIDDAEYHCNKTQVRKVISGVVGAASSVTSIQVANLLRLFRIPQVSYFSTSPELSNKQRFEYFSRTIPSDHYQVKAMVEIVKRMGWSYVSIIYEESNYGIKAFEELEELLARHNICIAIKEKLVKDSGVAEDIAYDNIVQKLLTKPRARGAIIFGSDQEVRQVMRAVRRANATGSFSWIGSDGWSARNLVSDDYEPEVEGTLSVQPQANPVRGFEEYFLSLTVENNQRNPWFVEFWEDHFQCRYPGSTSTPYNNYTKQCTTKERLSRQNTDFEDQLQFVSDAVMAFAYALRDMHRDLCGGGPSLCEAMKPTKGADLLKYLRKVEFEGLSGDEFRFDGNGDGPARYNIIHFKQSQAGQYHWVKVGEYTEGELRLNMTEVKFKRLSPKPPESVCSLPCLVGQAKKYVEGESCCWHCFNCTTYQIRHPDDETHCKLCKLGTLPDAHKQYCRPIPEIYLRPESAWAIGAMAFSATGILVTLFVMGVFVRHNDTPIVRASGRELSYILLAGIFMCYGVTFALVLKPTNIVCAIQRFGVGFCFTVVYAALLTKTNRIARIFKAGKQSAKRPSFISPKSQLVICACLVSVQILINGVWMVIAPSHAMHHYPTREDNLLVCDSYIDASYMIAFSYPIFLIVICTVYAVLTRKIPEAFNESKHIGFTMYTTCVIWLAFVPLYFGTANHVPLRITSMSVTISLSASVTIACLFSPKLYIILIRPERNVRQSMMPPRYGNMHRTAGTGPSSMMAAAVVTAATCAQEEKIQKHITPTNTENSLKTKKLCEMATQTISSIITSLDINAYNQIPYADQYVPNNATTATTTPTDKGSGNGNSNSNSNTNGSSNSNSNSNGDGDVATEQVVANNNKINQRQHGQPAVAFAITSTNNHISGPAATITTTAATGETTTEALVATITTPLATVDGSETMSVAPNNGHGNNGSQRPPVLQTNL
Protein: NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) (A3F7Q3)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MATKVYIVYYSMYGHVEKLAEEIRKGAASVEGVEAKLWQVSETLSEEVLGKMSAPPKSDVPVITPNDLAEADGFVFGFPTRFGMMSAQFKAFLDATGGLWRTQQLAGKPAGIFYSTGSQGGGQETTALTAITQLVHHGMIFVPIGYTFGAGMFEMEQVKGGSPYGAGTYAGDGSRMPSELELAQAFHQGKYIAGITKKLKTAA
Protein: Cyclin-dependent kinase 7 (EC 2.7.11.23) (Cell division protein kinase 7) (D6R9G1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
METDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
Protein: Phospholipase A-2-activating protein (PLA2P) (PLAP) (P27612)
Organism: Mus musculus (Mouse)
Function: Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (By similarity). Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (By similarity). Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:28413018}. Cytoplasm {ECO:0000269|PubMed:28413018}. Synapse {ECO:0000269|PubMed:28413018}. Note=Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains. {ECO:0000250|UniProtKB:Q9Y263}.
Interaction partners:
- Ubiquitin thioesterase OTU1
- Ubiquitin recognition factor in ER-associated degradation protein 1
- Transitional endoplasmic reticulum ATPase
- Nuclear protein localization protein 4 homolog
- UBX domain-containing protein 6
- NSFL1 cofactor p47
- Fanconi anemia core complex-associated protein 100
- UBX domain-containing protein 2B
- FAS-associated factor 1
- UBX domain-containing protein 1
Sequence:
MASGASRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFLGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYFGHTNYIYSISVFPNSKDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLENGDIVVGASDGIIRVFTESEERTASAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLSEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQTADPFTGAGRYMPGSAGMDTTMTGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGTAPEEKKLTEDDLVLLEKILSLICNNSSEKPTAQQLQILWKAINWPEDIVFPALDILRLSIKHPNVNENFCNEKGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYVSVSEPAKVSECCRLVLHLL
Protein: Interleukin-1 receptor-associated kinase 3 (B0UYS2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Myeloid differentiation primary response protein MyD88
- Interleukin-1 receptor-associated kinase 1
- TNF receptor-associated factor 6
- Interleukin-1 receptor-associated kinase 4.
- TNF receptor-associated factor
- Interleukin-1.
Sequence:
MKHPNIITFTPGSTRNMSGNTEPSTLLFDVPPVLMESFCRLMDSGVDGLGWRTLASRILSSQLEVRCIEMYAVAGKSPTKELMWSWAQRNKTVEDLLKVLDEMGHARARSLFQSQDSCVLKSSSPPHYPTYLRSTGKSCQVSDLHAESVSVEGEKQKCFITYFDVIEGTRHFHQDLKIGGSGFAEVYCGRWGNRSFAVKVFKQENKTDWKALWEKFTKEIEVLQLNQHPNILELWGSFSDSDRFCLVYPFLQNGSLFHRLHEHVDKPLSWQERLNIIKGTAKAVHHLHTSQPCTVICGNITSSNILLDENMQPKLCDFGLARLRPHSVDQSCTIVMNTALHSNLGYLPEEYIRDGKLSVKLDVYSLGVVILETCTGQKVKQESSKNLFLRDVLHSEVEEKGCVDACLRFLDLKFEHWPPAVALCLLRLGLECTGSKMRVRPDMEMVLQRLIPLHPLPAFSEDQPHTLDDTIPPQRPYKSFPIEDDEMHSQLEELHSPRVSKPADPCECSQSEVTFLSNEDRSFLRDCHQESDQRVSSSESVHSDSAARLDLYGSWPVECSCSTETEAQACADCCANGFSQSVVYVTIDDDNALPAPNDARNPAKEKMKNKIHLYNQGLIKTEELLSLQSE
Protein: Lys144p (A0A1D8PJ02)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Zinc finger PHD-type domain-containing protein
Sequence:
MGSSSPNPTKSPLGETSQQEATTTTAKPTKKVIKKSKYSRGGCAECRRRKIKCDELKPYCHNCTRLNKLCVYPTKPKFKFETPKTTLNNDNNMSNDQALPNGNNIGNNSVSYQFLHDKSNISNLQIYYNETQKRILNGSNGNNIPNLQQHQQNVIPYIDTGNLGTLPPPHHHRPPTKKFKISDMLSPDNDNQSNTTTTNNNSNNRNAYDFINMDYYNWDTLPITDIQNLFDDASLLVQDSLGLFTALENELNLPINADENNFGENNNNDIQLPILDSSSDKVSSSNSPSTTLSPSSFAVPQKSLSNKKLIEKTLLMHDIQGPHKLYLDKLTKTKLSYHVYPFAESIETNQVLRILLQYSLGSPYLLTAILATSATFQFIETRQMIHKDHQFKYTNISLKYLSEAFPQESNKDIHNSNNSGTTDNANFKMMTKDVEKLLLTILVLTLNFTALAYFQSNNRDGSTGISSVNKNNWKIHLRGVKDLLLKYSKLAHSNNQQYITDGLALAKTWFFAIESVAELNDPLGGTIKYSTKNISSHVDIIKTNQNVLDCSDSSRLWVETGYFNRGKNQDYHDALYRIGMVTNPNLPISTQFNMFLGFSIDVVKLIDEMTKSLDLLRENKPGQLSGTSIANIFTLISRARNNDIVPKVNKETFVIPKESIGHPEYKEFDKLVLPKSCYTHEIINDNSTTTSKDGSSKETIYYSWYDWSEQLHIDSVYMKLFHIKGLMKLPRDHPLVQELKDKVLTSMFFLKDKQQNIVDKEINNDSKIFLESDHYYLHSDLFDTRAIMAQSSYRECIKIANGLLDFEKLELYFQGLIKLGNGSSLLALDNVKRFKQNFIDGKDVEDDVDLAFDSEIIPFS
Protein: BCL2 interacting protein 3 (BCL2/adenovirus E1B 19 kDa-interacting protein 3) (RDCR-0202-2 protein) (Q9ET45)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
- Gamma-aminobutyric acid receptor-associated protein
- Apoptosis regulator Bcl-2
- Bcl-2-like protein 1
- GTP-binding protein Rheb
- Microtubule-associated protein 1 light chain 3 alpha
- Gamma-aminobutyric acid receptor-associated protein-like 1
- FUN14 domain-containing protein 1
- Gamma-aminobutyric acid receptor-associated protein-like 2
- Microtubule-associated protein 1A
- Beclin-1
Sequence:
MSQSGEENLQGSWVELHFSNGNGSSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRAEIDTHSFGEKNSTLSEEDYIERRREVESILKKNSDWIWDWSSRPENVPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSADFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF
Protein: DNA polymerase (G0YV93)
Organism: Pseudomonas phage PaP1
Interaction partners:
Sequence:
MQQRFETIEQYLEWMGNNNVTNMTWDIESTGLLDETSIDYTASPYKIKPSYSHHCVVVEEHGGNILAFYDGPTYVFDGREYTEKLPKASSMLHTEEVVTLKDYTPVEYIHLPLKEFKNYVLKRKIKRVVAHNMINFDLMSMKLVEDMDFTIGVEHRDGGLTTWSADTWMGKQVVFDDTLVISKTCNPDLFGGHSLDKLSRRAGGDTKIDFRKHLAPDVRFLDFAADMLYYCIYDVKANTAVWHWLQDHEDYQLSDRDNYIKNWLSPIQLEKKVAEIITYQEHRGFVLNVELCEKAVKDLDAKMEERRARVEPVLPPRPATKKFMADYTPPVRQFKKNGEITTYLQKFIEKIGAQLKEGDDRTMIFEGKEYKLPLPADVPLKTEMPAKIGDTTHIKQWLMGEFGWIPSEWKETDLTVDQKKIKLPMENIVAKIDRWLDVTYSTAYKEERLDGFGDYMKITPRSTRAYVRQRLIDRASKGGCKVLTNPSFTKGQEKEMCPDLERIAEQFPFAKDVIEYLTFKHRRSAILGGGMDWDEMEDGEEPEKGYLASIRQDGRIPTPADTCGAATSRMKHRKVANVPRITSLYGAELRELFGVEDGYFQIGYDFDSLEARKESAYCDQYDPTKEYCKSLMMEKPFDVHTMMAKRISEIIGRQFNRSPAKNVKYGCTYGAQAGKVAKTIGADLQTGQLVFDAFWDAAFPLKALKDDLTKQWEANGKKYIVGVDGRRVPTRSAHAILNSLFQSGGVICAKRAMVIHDQLLEKEGLKVDFFKEDWKNKPEFCQQMIAYHDEAQLEVTAKSVSFKMFPWSLVGGKPEGEKEREAAEKELKALAQAYKDEQLATTGKVWSDIAHYSKGEGGVFVAYCRAGELATKAVGAAGEFYSTPLVPIELTAGYIVGRSWKDCH
Protein: Major royal jelly protein 1 (56-kDa protein 4) (p56kP-4) (Apalbumin 1) (Apisin subunit MRJP1) (Bee-milk protein) (Royal jelly protein RJP57-3) (RJP-3) (Royalactin) [Cleaved into: Jellein-1 (Jelleine-I); Jellein-2 (Jelleine-II); Jellein-4 (Jelleine-IV)] (O18330)
Organism: Apis mellifera (Honeybee)
Function: Induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vitellogenin (Vg) and juvenile hormone, and reduces developmental time by increasing the activity of mitogen-activated protein kinase and inducing the 20-hydroxyecdysone protein (20E). Most abundant protein found in the royal jelly which is the food of the queen honey bee larva. The royal jelly determines the development of the young larvae and is responsible for the high reproductive ability of the honeybee queen.
Subcellular location: Secreted {ECO:0000269|PubMed:14709007, ECO:0000269|PubMed:15203237, ECO:0000269|PubMed:15607658, ECO:0000269|PubMed:15693061, ECO:0000269|PubMed:19203288, ECO:0000269|PubMed:20017154, ECO:0000269|PubMed:31410279, ECO:0000269|PubMed:9395329}. Cytoplasm {ECO:0000269|PubMed:19203288}. Cell projection, rhabdomere {ECO:0000269|PubMed:19203288}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19203288}. Note=Incorporated into royal jelly and pollen-bread (PubMed:14709007, PubMed:15607658, PubMed:15693061, PubMed:20017154, PubMed:31410279, PubMed:9395329). Found in the cytoplasm of neuronal cells in the brain, associated with cytoskeletal-like filaments (PubMed:19203288). Also secreted into the intercellular spaces of the mushroom body (PubMed:19203288). It is unclear if this protein is found inside ommatidial rhabdomeres or is secreted into the intercellular space of the rhabdom (PubMed:19203288). {ECO:0000269|PubMed:14709007, ECO:0000269|PubMed:15607658, ECO:0000269|PubMed:15693061, ECO:0000269|PubMed:19203288, ECO:0000269|PubMed:20017154, ECO:0000269|PubMed:31410279, ECO:0000269|PubMed:9395329}.
Interaction partners:
- Apisimin
Sequence:
MTRLFMLVCLGIVCQGTTGNILRGESLNKSLPILHEWKFFDYDFGSDERRQDAILSGEYDYKNNYPSDIDQWHDKIFVTMLRYNGVPSSLNVISKKVGDGGPLLQPYPDWSFAKYDDCSGIVSASKLAIDKCDRLWVLDSGLVNNTQPMCSPKLLTFDLTTSQLLKQVEIPHDVAVNATTGKGRLSSLAVQSLDCNTNSDTMVYIADEKGEGLIVYHNSDDSFHRLTSNTFDYDPKFTKMTIDGESYTAQDGISGMALSPMTNNLYYSPVASTSLYYVNTEQFRTSDYQQNDIHYEGVQNILDTQSSAKVVSKSGVLFFGLVGDSALGCWNEHRTLERHNIRTVAQSDETLQMIASMKIKEALPHVPIFDRYINREYILVLSNKMQKMVNNDFNFDDVNFRIMNANVNELILNTRCENPDNDRTPFKISIHL
Protein: Protein N-terminal glutamine amidohydrolase (EC 3.5.1.122) (Protein NH2-terminal glutamine deamidase) (N-terminal Gln amidase) (Nt(Q)-amidase) (WDYHV motif-containing protein 1) (Q96HA8)
Organism: Homo sapiens (Human)
Function: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q80WB5}. Nucleus {ECO:0000250|UniProtKB:Q80WB5}.
Interaction partners:
- E3 ubiquitin-protein ligase UBR2
- Protein N-terminal asparagine amidohydrolase
- E3 ubiquitin-protein ligase UBR1
- Arginyl-tRNA--protein transferase 1
Sequence:
MEGNGPAAVHYQPASPPRDACVYSSCYCEENIWKLCEYIKNHDQYPLEECYAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQNFIYDLDTVLPFPCLFDTYVEDAFKSDDDIHPQFRRKFRVIRADSYLKNFASDRSHMKDSSGNWREPPPPYPCIETGDSKMNLNDFISMDPKVGWGAVYTLSEFTHRFGSKNC
Protein: Required for respiratory growth protein 7, mitochondrial (Q08774)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Required for respiratory growth protein 9
- Genetic interactor of prohibitin 5, mitochondrial
- Required for respiratory growth protein 8
- Increased recombination centers protein 19
- Glutamyl-tRNA
- Mitochondrial 15S rRNA processing factor CCM1
Sequence:
MIKNYLGRRWLNNPAIQAYVKQNAAVAHSTVFQGNLYEYTVMRELSEKLRMTKLRKTGGAHDGGVDIKGSWPVDDIYWKISSLMPNLEMASNIKRTNSQNGFVLKPLKYRIIDHTFEPLKVLVQCKAFTKSKLSPREFRELVGTFTSLVSHSQRNKTVCIMCSPHMLTKDTLNLINNITLPLIYLRVEMLKEKTDGHFDLINSGKLINYYENSYASTLMQDCKISEWLKLKLYKNSDFNSEK
Protein: Translocator protein 2 (Peripheral-type benzodiazepine receptor-like protein 1) (Q5TGU0)
Organism: Homo sapiens (Human)
Function: Cholesterol-binding protein involved in the redistribution of cholesterol from lipid droplets to the endoplasmic reticulum. Required to meet cholesterol demands during erythropoietic differentiation. May play a role in transport processes at the plasma membrane of erythrocytes, including regulating VDAC-mediated ATP export, and import of the heme precursors protoporphyrin IX and 5-aminolevulinic acid.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19729679}; Multi-pass membrane protein {ECO:0000269|PubMed:19729679}. Cell membrane {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:31989647}; Multi-pass membrane protein. Note=Localizes to the plasma membrane and intracellular membranes in developing and mature erythrocytes. {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:31989647}.
Interaction partners:
- Glycophorin-A
Sequence:
MRLQGAIFVLLPHLGPILVWLFTRDHMSGWCEGPRMLSWCPFYKVLLLVQTAIYSVVGYASYLVWKDLGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPINKLAALLLLPYLAWLTVTSALTYHLWRDSLCPVHQPQPTEKSD
Protein: Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (B4E1C5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC
Protein: Cytoplasmic dynein 2 light intermediate chain 1 (Q19119)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
- Dynein light intermediate chain
- Cytoplasmic dynein 2 heavy chain 1
- Dynein light chain roadblock
- Tctex1 domain-containing protein 2
- WD_REPEATS_REGION domain-containing protein
- WD repeat-containing protein dyf-2
- Intraflagellar transport protein 52 C-terminal domain-containing protein
- Intraflagellar transport protein 88 homolog
- Intraflagellar transport protein che-13
- TRAF3-interacting protein 1
Sequence:
MNIWDLAKQKLVENKQRAAELKQKLDDENGTQSDNYLSEVRRRHESHIIFAGNRKSGKSSFMLNFLERKEDLKDSVGLEYTYARRTRGNVKDIANLWELGGGATVTELLSVPITMKNVEICSLILLLDMTNLDEMWITIEKTVDSVRRLVENLERQDINLQTRLAEKMRLRLEKYDDGSLKMCNPCPIPVTIVASKYDEFQNFESEKRRHLCQFLRFLAYSYGANLMMFSSRMEQFPKLVKNMTSHFAFGTVCPQGYMTDHNKPMFVKCGFDSLESIGIPPASDNFMGASSPFNLWRESFISLWPQKTGTIDIEDTKKQDPMIDPVFKEPNIDNLVEIKRKELKNHIRSKRDREAAEARAADRIAKINVR
Protein: Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) (Q8TCX1)
Organism: Homo sapiens (Human)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles. Involved in the regulation of ciliary length.
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:11907264}. Cytoplasm {ECO:0000269|PubMed:26130459}. Cell projection, cilium {ECO:0000269|PubMed:26130459, ECO:0000269|PubMed:29742051}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:26130459, ECO:0000269|PubMed:29742051}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q8K0T2}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:26130459}. Note=Localizes to the apical cytoplasm. {ECO:0000250|UniProtKB:Q8K0T2}.
Interaction partners:
- Cytoplasmic dynein 2 heavy chain 1
- Cytoplasmic dynein 2 intermediate chain 1
- Cytoplasmic dynein 2 intermediate chain 2
- Dynein light chain 1, cytoplasmic
- Dynein light chain roadblock-type 1
- Dynein light chain Tctex-type protein 2B
- Dynein light chain 2, cytoplasmic
- Cytoplasmic dynein 1 light intermediate chain 2
- Dynein light chain Tctex-type 3
- Cytoplasmic dynein 1 heavy chain 1
Sequence:
MPSETLWEIAKAEVEKRGINGSEGDGAEIAEKFVFFIGSKNGGKTTIILRCLDRDEPPKPTLALEYTYGRRAKGHNTPKDIAHFWELGGGTSLLDLISIPITGDTLRTFSLVLVLDLSKPNDLWPTMENLLQATKSHVDKVIMKLGKTNAKAVSEMRQKIWNNMPKDHPDHELIDPFPVPLVIIGSKYDVFQDFESEKRKVICKTLRFVAHYYGASLMFTSKSEALLLKIRGVINQLAFGIDKSKSICVDQNKPLFITAGLDSFGQIGSPPVPENDIGKLHAHSPMELWKKVYEKLFPPKSINTLKDIKDPARDPQYAENEVDEMRIQKDLELEQYKRSSSKSWKQIELDS
Protein: Integrin-linked kinase (Q9NHC7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm, myofibril, sarcomere {ECO:0000256|ARBA:ARBA00004204}.
Interaction partners:
Sequence:
MEDIFHWCREGNSIQVRLWLDETEHDNNLGDDHGFSPLHWVAKEGHAKLVETLLQRGSRVNATNMGDDIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNTPLHYACFWGYDMICEDLLNAGAQVGIANKDGHTPLEKAKPSLAKRLQDLVEKSGREVKVISFKEQSWQGLKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRISRDFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRLSLFSLLHGATGVVVDTSQAVSFALDVARGMAFLHSLERIIPTYHLNSHHVMIDDDLTARINMGDAKFSFQEKGRIYQPAWMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWSPMECGNEIALEGLRVKIPPGTSTHMAKLISICMNEDPGKRPKLDMVVPILEKMRR
Protein: Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) (Q99PD7)
Organism: Mus musculus (Mouse)
Function: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9HC58}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MPPPGDQDCARRRSRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLIGEDRKWMVGRKLMQVNDTLTSEDAGLQSSKNCTEPALHEFPRDIFSNEDRRQGAVVLHVLCAMYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDIVAETDNETENENEDNENNENDEEEEEDEDDDEGPYTPFDPPSGKLETVKWAFTWPLSFVLYFTVPNCNKPHWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLFLYGVFLCFSIMTEFNVFTFVNLPMCGD
Protein: Geranylgeranyl pyrophosphate synthetase (A5E2T5)
Organism: Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Interaction partners:
- Diphosphomevalonate decarboxylase
- Farnesyl pyrophosphate synthase
- Isopentenyl-diphosphate Delta-isomerase
- Squalene synthase
- Alkyl transferase
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Hexaprenyl pyrophosphate synthetase
- Alkyl transferase
- ditrans,polycis-polyprenyl diphosphate synthase [
- Protein farnesyltransferase subunit beta
Sequence:
MDYKKVVNSLAQPTVVDPAVIEPYKYIRKLASNNNNVRSRFINAFNETFFHITDQEVLQLINEVIEILHNASLLIDDVEDSSNFRRGYPSAHMKYGVPLTINCGNLMYFEAIEKVYNLWRLKLGKEDTTLATLALVWEIVMPEMKNFHKGQGLDIYWRDNLPDLESLPSVVDYCQMAKDKTGGLFRLAVRLLRLFSSGSTHLDSEYNGVFESIANCLGVIYQIRDDYLNIVDERYSHMKGIRGEDLIEGKLSFPILVSLTKDFNQKHTEISSLSPLYELLYNHRSTEERLRRRDLHDQAIEQLESPDIVSETNRLLQELKAQACRLIMENARDANPLMIMVDTLCTI