Protein: Inositol 1,4,5-trisphosphate receptor (Q57XB2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
- Adenosylhomocysteinase
Sequence:
MSQSRVPIRYGAFIHLSCDEGYVTAGGLGNEGLFIRNKNELSDDAEPLPLFGFETSVFQILPPTVAKVAAEEGLSKGNRAPNSNPLSDGVSNIYSTQQVTFGQLFVLVHAVSRLHVAALPSEPSERDPDCARLVLAPPGEIEQTFCQFIFTPRYTTHGEGDVVCRGDEVLVQLSSIPIFLQTTVVSPTRPVKHETFGSASFPYEPTDGCGRGNSWSAGTRMALSAVLGAPEVNLSEAKALVFVVERYDIDRDKAEHQRILHRIPRPCVSAGVPVIFYHLEHKRVLATSVAMPPCQGGGKIGVSGVAPRGNEGGGERDHLLKTRQTHSVMGNVTVICHASGRFAAAGSSKSQGSDSHSAGATSLDSDPCSTKGKAPDDRKRVNGVGGAALPLFAVDKGVADGTFSEEGALSGLQCSCTALWILENEQPTVGGAVNMNSGVYRLRQACSNLYVAVEGSAVDTILEGDGSPEGSVVSQRSCCNLTGDIVNEEGGDVVRPTTLSMIPPPRTPKDLQRTLFRLSPMFNTDCGYLIENDCLLLQNVATDMYLCTSEGSETLSLSWKPSNIDLIVVRRAATDVQDSVLFLWSQCETLSGYRDAFQVLTTEGTATHQQQTETDGEHGQGRYPSAEGSTSPTLMEGRMAIVSDYNHIPESFVRPSKTCPKGSNVGTGYASLLPVICACQRTLAELIIFCSISPERNVLRRDGIPIPNHQHMLVELCVHRLVIDVILAPFSKFGVRADRSVGKHAQCCGQWGCSSWLPPLPLSGGVVDVNDLLLKMHREIHIVCRLGFRLLRQMVRQAPELKAGFENYIPYFLAFDGYKLEVVDSLTRLFSENPAVRNSSLELVVNHYIAGLHLTRSGRYLQLLCSMCSVGTHGVTERQRLVCQKLLVENANALYSFVLDSGGEWAVKTDKDEPPIPCNILFSGQQQDGGEEEGTKLREYVQSELELLGALCLDGCPPLCREEVAKVFPSPVLLMALRNFSPKWPEVSDRSRVCDVVRSHLIRLAMHCYILPYIDDPAVQLREGAVLLGSSKLHLKVDEKTAFSGKPDSELTQAVKEGTLHVIRSNTHFVRSDTGRSILIRAALAAWLRFVSAHQVSATETACLVPLLLELLDSRDDEAHDGSSKIAEYTWTRLEVSEAGLLVVRAREMICQILLQILETATYRAANEINLLLHGILVTDHGASLAHQHDYCSLLRRADVSSTGDPFVTSPTERDALLWHKGKANDGNGNRCFGLNRRKGPSDYQSTVAGSAVTTQLSGSTKDVAAFLDYVKGICSCIVRPLRVDQLVPRLVDLAHHDGSQLAPYAMELLVRICTVRRSVARLVLQVHPFPSSEVIQCFDNMYFAAVQVRSSYIRGSVEEAIDVALQGIDGLSTQTQNEVTGTTNEGRVDDGGTDEYYNDLTEDDEEIEEIGICEEQEVEASSSSAPEDQHEVGGESKARRLWSKAAGAARIVVYRNAIIARRRSVGLSETSRVPLRVVVRAETVRHWQVHITMLEMYPFIGPSSPAFSKWMRFFYVFTLSQSNAESLKAYIDIFMGAFNLSSNCVVMGLHIVLSILATIKDPTPHLTDAFLRESARYIDGEIAALHPDGEFATKLGLHVFTKTTVGGIPRRRMLQLLRDYDAFRCLPSPGVTEKHGRGRFTACIVEMVCRICGTSMGAVALGRSALPVTHLLEITLSYGTSYTPLVEVPRPRALWESNSFHLLGAYLLALVSLYIAAGDAGGDGGRRQRQMEWMANRDWWSVVLLLSRQLKELTRLMQSRTETVLWRGRRILQRYRRLWLVNLPLALLTFMTECFNEAGFYRYRDVVGATFHEMCMSVAGFSEVLLASADAIRLQAREMVGYRRLVALLQVQTGNLVGHELLSGTMLTTRRNLRHGVICYYKKINEAEEEARGLHPDALLLAETGPQAENDGIQGGLIATADVPTHTQNDADDSSPMGLLISGAATKCLDAERLRGALRSLVNRDQLITMEDSTDLGEPAGIMNALLLSCRERSNVLDFVSTTLGCMRERSFGSITLIGMLNIFSNALHTALREQERERLKHVSAENSSVITDIFTVRSFETDYAKENAGRLLQTTFSDLGATRAIASLCAVDDQVVAYSAVQLCVGLLEGGNEHAQKALLAYFQEHQERFFHNIRDMLHKAVDWVQCTNAEHQIVVLERGGVVPNVSNAHEFTRMLLTNALTTPPSLYSSLKVRVGRGTAVARRRLSAWDRAGGSLNQRFVCTLFRMLQLFCEGHNLSMQNYIRSQYDNLHSVNAVHEVMNLITEIAAVVHPATVRMLQSAFALLTELCQGPCHENQEALLGYGVCVVISKLLSRLNLPDVTGTPSTGTGITNWGGGDSNSTDNKASVDCCTLNETDSEGNAFLRLQGGFLLSKDDAGNLRIALTQCLLSLIEGCRSRDVFHQLLEQIPVEVIERELTTVDPGAYDSILENEELASDPGVEALFNWLIFLKTVRPYAEADYLKRIDAMLQHTNKLCTRLGFIEIQRADGMLEKVLFRIPHVWRGLMRRNRKQMLAEINCSSRAAKLGDFMYHSDNVIFEVERSYAFQCWVERRTRWRLDNRSSGWRGKECDAGKVDTSVDAGKPRWTPKWKQCSDAPKYFWNHFIAPVLFCTHLGFYEYSSLLVAVVLNIALINGEGRHRNLEESQLWANIISGLCVLQLVLSLIAITVDTIVFFPVSLYVHYRQKQQRFSGRAKFNETLQGVLRGLSAKEISLLLVTRFSFQYRLLLVVMAVLSIFVSYYFAAAHLTLMVYTFPTLRTFVSAITHNGRQLLLTALLGVMGLYLFAIAGRIMFPEQFGSNGEVDENSGKKNDENGNCDTLLRCFTFILWQGLRQGGGVGDVMDEVSWNSSTLVPRVSYDLIFFALVNVVFLNIMFGIIIDTFGELRDDRRERENELRSTCFICGLDADTLEKGQVGGFRAHVEDAHNMWMYLYFIHYLRHKDPNEFTGQESYVHEKIQRNDLSFFPEEDCLALQECREGNGKRTGDDEADSDDELASSVVVGGSAPRGPKPESAHPDTGVKLVLKELAAVREAVSALAREATMEGERTRGLAQQLELINRSSQSSSLRKFPGGGSAASVAETSTSKGTWLRHSEPEH