wanglab/gogpt-training-data huggingface dataset:
Protein: RNA-binding protein, putative (Q385I3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPVLPEFIPLGKQKEMFAVSSWRDSPQASTPALSNVANQPMSPALLPAAQCEKDVGQQGKGQRTRKSKGRGKNQSSQRQPDVEDFFVNFVLPPGISFANIKEELQLFATTPLHIYDVGPPHTLLVKKSTGAVGNADADVSAASQQADGTAPLIDKGVSKCAAHEQSPIRTPNIMCGVTADCSGEVAGAAMPGISLPPSIPAETLSKGYLISLLFAESSEAEKVSELLKKKWPQSTVTIVPRNRSMLNASLVLKGLPNLPKTEVIIEELDKIIPHKPSYIRLHRGERGVFKNVVFIKYPNREIAEECKLRLERLYIGSRPLKVEFKKKEKPAAEKDEGMTLQQLVRDLRVSSEHEGFRYQRSDLSKEDLKVLKQLCNSYGLSFDLDDRTVTVRRILPLSGRPSPAMRPAAANGCASHTLTATMPTPGTLQPMDFRGIRHWRELNSQQVSLGIARPKEPGSVQPFAPGRGRPL
Protein: Protein EMP47 (47 kDa endomembrane protein) (Endosomal P44 protein) (P43555)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the secretion of glycoproteins and in nucleus architecture and gene silencing. Required for the endoplasmic reticulum exit of EMP46.
Subcellular location: Golgi apparatus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Interaction partners:
- Protein EMP46
- Endosomal protein P24B
- Coatomer subunit alpha
- Protein transport protein SEC23
- ER-derived vesicles protein ERV46
- Protein RER1
- Coatomer subunit gamma
- ER-derived vesicles protein ERV14
- Endoplasmic reticulum vesicle protein 25
- Protein ERP2
Sequence:
MMMLITMKSTVLLSVFTVLATWAGLLEAHPLGDTSDASKLSSDYSLPDLINARKVPNNWQTGEQASLEEGRIVLTSKQNSKGSLWLKQGFDLKDSFTMEWTFRSVGYSGQTDGGISFWFVQDSNVPRDKQLYNGPVNYDGLQLLVDNNGPLGPTLRGQLNDGQKPVDKTKIYDQSFASCLMGYQDSSVPSTIRVTYDLEDDNLLKVQVDNKVCFQTRKVRFPSGSYRIGVTAQNGAVNNNAESFEIFKMQFFNGVIEDSLIPNVNAMGQPKLITKYIDQQTGKEKLIEKTAFDADKDKITNYELYKKLDRVEGKILANDINALETKLNDVIKVQQELLSFMTTITKQLSSKPPANNEKGTSTDDAIAEDKENFKDFLSINQKLEKVLVEQEKYREATKRHGQDGPQVDEIARKLMIWLLPLIFIMLVMAYYTFRIRQEIIKTKLL
Protein: Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2) (O95140)
Organism: Homo sapiens (Human)
Function: Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (By similarity). Plays an important role in the regulation of vascular smooth muscle cell proliferation (By similarity). Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PRKN recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress (By similarity). Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions (By similarity).
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:11181170, ECO:0000269|PubMed:11950885, ECO:0000269|PubMed:12499352, ECO:0000269|PubMed:23620051, ECO:0000269|PubMed:26214738}; Multi-pass membrane protein {ECO:0000269|PubMed:11181170, ECO:0000269|PubMed:11950885, ECO:0000269|PubMed:12499352, ECO:0000269|PubMed:23620051}. Note=Colocalizes with BAX during apoptosis. {ECO:0000269|PubMed:12499352}.
Interaction partners:
- E3 ubiquitin-protein ligase parkin
- Serine/threonine-protein kinase PINK1, mitochondrial
- E3 ubiquitin-protein ligase MARCHF5
- Mitofusin-1
- Non-selective voltage-gated ion channel VDAC1
- Mitochondrial fission 1 protein
- Dynamin-1-like protein
- Mitochondrial antiviral-signaling protein
- Mitochondrial Rho GTPase 2
- Mitochondrial Rho GTPase 1
Sequence:
MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDTYRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
Protein: RING-type domain-containing protein (Q385T2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAVAYVFDGAVLKQMSLEAGHPKFTVLDTPLCSDSAVTCFGKDEFYFINGSVPNVLRHFGGRSGCTEHFLPGPAHCLLVHRQKVYCCGVDCLYVFDPLGEEVETIELGQQIKELTAADHGFVFVNDRHELYAFHFTRGVKIVGTKGPVSKLLGHHNRYAVVLLDNGDVISVNEEAEVRENLFPLKIKERFVALDTGMTLALREDELALHMNGTWLCLDGFKGRELQFLGVPLTPAEDACTICFCDFEDGDGVRLDCGHPFHRDCLAEFSTHAKSFVEKGEHIVFTYAVCPSGCGTHIRHAAAPLSAYMNDLYRAVTKDAEGRLREMENKTLEDLYYYVCCRCEKPYYGGNRWCSRTISGEPCKKPSELICSDCNDDFLCPSHNHDFVLYKCRYCCNPATHLSFGNRYMCDACNKKWEGTEPEPMECPGAEKCPLGGAHPTGGSQPLGCMLCTLFDKCDAKHFFPPQ
Protein: Growth-regulating factor 1 (ZmGRF1) (Growth-regulating factor 6) (A0A060D764)
Organism: Zea mays (Maize)
Function: Transcription activator that plays a role in the regulation of cell expansion in developing leaves. Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function and the transition between cell division and cell expansion in growing leaves.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU01002}.
Interaction partners:
- C2C2-YABBY-transcription factor 12
- Beta expansin8
- 14-3-3-like protein GF14-6
Sequence:
MAMPYASLSPAGAADHRSSTATASLVPFCRSTPLSAGGGLGEEDAQASARWPAARPVVPFTPAQYQELEQQALIYKYLVAGVPVPPDLVVPIRRGLDSLATRFYGQPTLGYGPYLGRKLDPEPGRCRRTDGKKWRCSKEAAPDSKYCERHMHRGRNRSRKPVETQLAPQSQPPAAAAVSAAPPLAAAAAATTNGSGFQNHSLYPAIAGSTGGGGGVGGSGNISSPFSSSMGGSSQLHMDSAASYSYAALGGGTAKDLRYNAYGIRSLADEHNQLIAEAIDSSIESQWRLPSSSFPLSSYPHLGALGDLGGQNSTVSSLPKMEKQQPPSSFLGNDTGAGMAMGSASAKQEGQTLRHFFDEWPKARDSWPGLSDETASLASFPPATQLSMSIPMASSDFSVASSQSPNDD
Protein: Putative phage portal protein (A1BTV4)
Organism: Rockefellervirus CNPH82
Interaction partners:
Sequence:
MISINWPWDKPYHEQVVEQIKPKYETQEEMILRLVREHKENIDNITMGERYYNHHPDILDAPFKRDVNGDYDETKPDWRMYTNYHQNLVDQKVAYAVANPVTFGVDNDKALKQIQHTLNHKWDDKLVDILTAASNKGIEWVQPYVDEEGEFKTFRVPAEQAVPIWTNKERDELQAFIRVYELDGAERVEYWTKDDVTFYELKEGQLIPDFYRSEDHIQPHYYQGNKLMSWGRVPFIPFKNNPQEVSDLFMYKTIIDALDKRLSDTQNTFDESVELIYILKGYEGEDMKDFMHNLKYYKAISVAGESGSGVDTIKVEVPIDSVKEYTKMLRDYIIEFGQGVDFQQDKFGNSPSGIALKFMYSNLDLKANKLKNKTLTALQELLQYIIDFYRLDVRVQDIEITFNFNVMVNELENSQIAMNSTGLLSKETILGNHSWVQDPVAEMERIEQENIELNQQLPDIEEGLNDEQQRQSEDNQSE
Protein: Myricetin 3-O-methyltransferase 3 (ShMOMT3) (EC 2.1.1.-) (3',5'-dimethyl myricetin 3-O-methyltransferase) (Syringetin 3-O-methyltransferase) (EC 2.1.1.-) (3'-methyl myricetin 3-O-methyltransferase) (Laricitrin 3-O-methyltransferase) (EC 2.1.1.-) (3'-methyl quercetin 3-O-methyltransferase) (Isorhamnetin 3-O-methyltransferase) (EC 2.1.1.-) (4'-methyl kaempferol 3-O-methyltransferase) (Kaempferide 3-O-methyltransferase) (EC 2.1.1.-) (7-methyl quercetin 3-O-methyltransferase) (Rhamnetin 3-O-methyltransferase) (EC 2.1.1.-) (Kaempferol 3-O-methyltransferase) (EC 2.1.1.-) (Quercetin 3-O-methyltransferase) (EC 2.1.1.76) (M9Z1G5)
Organism: Solanum habrochaites (Wild tomato) (Lycopersicon hirsutum)
Function: Flavonoid 3-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as myricetin derivatives, aroma compounds possessing antioxidant properties and exhibiting pharmacological activities such as anti-carcinogen, anti-viral, anti-thrombotic, anti-diabetic, anti-atherosclerotic, and anti-inflammatory effects. Catalyzes S-adenosylmethionine-dependent regioselective 3-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates. Active with myricetin, quercetin, kaempferol, 4'-methyl kaempferol (kaempferide), 3'-methyl quercetin (isorhamnetin), 7-methyl quercetin (rhamnetin), 3'-methyl myricetin (laricitrin) and 3',5'-dimethyl myricetin (syringetin), thus producing 3-methyl myricetin, 3-methyl quercetin, 3-methyl kaempferol, 4',3-methyl kaempferol, 3',3-methyl quercetin, 7,3-dimethyl quercetin, 3',3-dimethyl myricetin and 3',5',3-dimethyl myricetin, respectively. Inactive with flavonol substrates methylated at the 3-hydroxyl position such as 3-O-methyl quercetin.
Interaction partners:
Sequence:
MALSMDNIVISNEEEIYMMKAMHIPCGLYLNMVLKAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSFLTCNITKNDDGIVHTSYNLTPLSQSLISDKDGSSIAPFLLLATDPVAVNSWFHFKDAILEGEIPFNKAHGVHAFEYHGKDSRMNGLFNRAMQNVTCTEMKRIVECYNGFQGVKEIIDVGGGLGISLATIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMFKSVPQRELILLKAILHDWDDEYCVKILKNCWRALPKDGKVVVIEQMQPEYPETNLISKNSSSVDMLMMTMLDGGKERTKQQFEDLAKQAGFTVFKIVARAYYCWVIELYK
Protein: Hes-related family bHLH transcription factor with YRPW motif 1 (A0A8I5ZYX7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
EALKDCHGLPEPKRQHPLIGAPGSAPRAGGHHPNERRLGRLFLQDPPTVRASRRWAPTAVPRAGRGQGLPGPAGARTPITGSHQEPGRRALAQPRSPARLFFSIHADAQSCRRRRQRGRRRRPSGLAGGRGAGTFPRPAARAAHRRRCRRGPGTRPGQSGRAGWGGSVAIAGLVSPAGPPFLPAAGPPPPAAPSRAPAEPTHCRRAGAGSRGGAQRAWSARPAPLRLPIRVARRRLAGARGCPGAAAPPLPQPPRLLRPPPIPGKGRSVGKGWLSFNQRLSVSGISVHAPPAAERRAAAQLTPPCPPRDPPGSPRSATMKRAHPDYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQVLARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHGGLGHIPWGSAFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLASAHPEAPALRAPPSGGLGPVLPVVTSASKLSPPLLSSVASLSAFPFSFSSFHLLSPSTPSQAANLGKPYRPWGTEIGAF
Protein: tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6) (C9K020)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MDALEDYVWPRATSELILLPVTGLECVGDRLLAESGFGFPKCPDYRREPPHPAETKDFLRFKLQDCEGPDVLVYSLDFGGHLRMIKRVQNLLGHYLIHGFRVRPEPNGDLDLEAMVAVFGSKGLRVVKISWGQGHFWELWRSGLWNMSDWIWDARWLEGNIALALGHNSVVLYDPVVGCILQEVPCTDRCTLSSACLIGDAWKELTIVAGAVSNQLLVWYPATALADNKPVAPDRRISGHVGIIFSMSYLESKGLLATASEDRSVRIWKVG
Protein: Homeobox protein Rhox13 (Reproductive homeobox protein 13) (F6YCR7)
Organism: Mus musculus (Mouse)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000255|RuleBase:RU000682, ECO:0000269|PubMed:18675325}.
Interaction partners:
Sequence:
MAHGVPFDHNYYIVECKEETNAEAQAGAMAATSTEEAPGAVEVAQAAVASSHDSGGAIGCATVKESESDSESESDSESESDSSDSSDESDDDSSTSDEDTSDPEEAAAPSVAAVAAAAAPPTVPAAAAIQIPGPYRYRPPRRHVRRRRRGPPFHFAQWQVEEMESLFEETQYPDLLTRGELARTLNVPEVKVKVWFTNRRAKQRKIERREMLRNIPPGAEDFIFITDFEEPS
Protein: High affinity iron permease ftrA (E9QT42)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: High affinity iron permease; part of the reductive iron assimilatory system (RIA), a siderophore-independent high affinity iron uptake mechanism.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Iron transport multicopper oxidase fetC
- GATA-type transcription factor sreA
Sequence:
MAKDVFAVPIFFICFRECVETSIIVSVLLSFIKQTLGQEQDATTRKRLIRQVWWGVAIGLFISVCIGAGMIGAFYGYGKDHFASTEDLWEGIFSLIASVIITIMGAALLRVTKLQEKWRVKLAQALEAKPLTGGTFKNNLKLWAEKYAMFLLPFITVLREGLEAVVFIGGVSLSFPATAFPLPVFTGILAGVAIGYLLYRGGNQASLQIFLIISTCILYLVAAGLFSRGVWYLENNTWNHVIGGDAAETGAGPGSYDIRQSVWHVNCCSPLVNGGGGWGIFNAILGWTNSATYGSVLSYNLYWIAVIVWFVAMRHKERHGRLPVVDPLLNRLRGRKSAEPGNGEQDVEVSTIPSDLQTESKIPKSGASLV
Protein: DIS3-like exonuclease 2 (EC 3.1.13.-) (O14040)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23503588}. Cytoplasm, P-body {ECO:0000269|PubMed:23503588}.
Interaction partners:
- Exosome complex component ski6
- Exosome complex component rrp46
- Exosome complex component csl4
- Exosome complex component rrp45
- Exosome complex component rrp42
- Exosome complex component rrp43
- Exosome complex component mtr3
- Exosome complex component rrp40
- Terminal uridylyltransferase cid1
- Exosome complex component rrp4
Sequence:
MDLKPNIRRKEKRNLLKGEAALEKKGSIDRKTKNKAYPSTTHDPHQNDDSNIPGLGSGLLERIKDIVQRPTDTQLKGQDSNHKKASLTETKTEKAKVKPKAKKKNSKEKISKSSKQDEHKTDVHKESVSKLSKNLESRNNRDENSAKREKNNSHQVEADTNNATEMVSSNAKKSVYPLYYDSATVKKGLKSGTLFKGTLRILENHRSAFACMEDIPDFYVDGPIARNRAFHNDVVIVEPVMNNDSPTEKSNFLQNGVEKVKIKDHDDELGGAMEHLERLEIKSVASFKGDSRTRARVVAIEKRAEISKIVGILRAPGWSLKNVEYVSKKSSYAIFIPKDKRLPFITIHKNDLSDLSGENWIENILKHHDQLFSVEITRWSIYSRYPMGVLGEKLGNITDVEAYTNALLLENGISSSPFSDEVLNCLPPDDWIISHEEIKKRRDLRNELIITIDPETARDLDDAVSCRALDNGTYEVGVHIADVTHFVKPDSALDKEAASRATTVYLVQKAIPMLPPLLCERLCSLNPNVERLAFSVFWKLDSNGKEIGKRWFGKTVIKTCARLAYSEAQGVIEGKSWDDAVGKPIGGTHTPKDVETSILTLCEISRKLRKDRFAKGAVEINSTELKFQLDEYGMPNKCEVYEQTDANHLIEEFMLLANRSVAEHISKNFSNNSLLRRHASPKEKQINEFCHFLKSMNFDFDASSSAAFNASMVRLRSTFNEELVELFENMAVRSLNRAEYFCTGDFGEKTDWHHYALSFNHYTHFTSPIRRYPDIIVHRLLERSLKNTSPGIDKKNCSLVAAHCNEKKEKSTTVQEDSQQLFLSVYIAEYCKKHDKKSMPVQAFATRISGNSIDVYISEYGISNRVDLSSDDRIKSFIVAPDDSSVKITLFDDSQKTIALTDRFQVYLYSDYSRTFFSIRCSLVSLN
Protein: Ligand-Gated ion Channel (G5EEC1)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Tyramine receptor tyra-2
- G-protein coupled receptors family 1 profile domain-containing protein
- Tyrosine decarboxylase
- Tyramine receptor Ser-2
- Neurotransmitter-gated ion-channel ligand-binding domain-containing protein
- Rab-3-interacting molecule unc-10
Sequence:
MVFSFILTFTISVVAAFDDECIKCDLRSSYCKTWENSTQSCECRDGFARISNGSCAMVSDLARGGLGLSQDSEEDEPFCVLGQAEKAATRILTELLSKYDRNLVPKMKGVDVDVELLIQRVSEISEIQSSSTMHILFSQIWHDPGLSFEHEEGAHCLTNLSLSHRMVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYRVVVESPCEMDFSFFPMDRVMCTTIFESYAFNVGKVRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKATFIYPAGVWDQLNIKLLFRRSYGFYILQIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSNVSRSLPKVSYVKGLDLFMFGCIVYIFLSIVELAVVGSLEQRKQQRTNADGDFLSDDDIKKNIFQRTFSTKSFKSGYGARHHQFSECASPEDGGEWPKTRTEWAERTYVECPEPEPPESNRHPEVENDSNNKMLVLVRQRRASRKRRKRLMSGKLFQRWTAEDMDRFCQKLFPITFTFCNLIYWMYYTAKSKD
Protein: CLaudin-like in Caenorhabditis (H2KYF7)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAMQFTGLQVVSWILLLVGTGMLVIALISDYWSIHQPRNQMDNLQMHRGVLRQCITTRQYGSCNFRLSSMFKQLRNFMDGYDMYSERSMYRHLPTQTYEVFVALFLAISCMIASTVLLFGPFCCQRCKPSTTLLIFITGVFSGSGCLIYWNANREGKTFTLQQLQFQDVYHYDYGSDMNILSWSFWMAVVSTGILLCSAFLLCML
Protein: SAFB-like transcription modulator (Modulator of estrogen-induced transcription) (Q9NWH9)
Organism: Homo sapiens (Human)
Function: When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis.
Subcellular location: Nucleus {ECO:0000250}. Note=Detected in punctate structures. {ECO:0000250}.
Interaction partners:
- RNA-binding protein 25
- Peptidyl-prolyl cis-trans isomerase G
Sequence:
MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF
Protein: Large ribosomal subunit protein uL18m (39S ribosomal protein L18, mitochondrial) (L18mt) (MRP-L18) (Q9CQL5)
Organism: Mus musculus (Mouse)
Function: Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA (By similarity).
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9H0U6}.
Interaction partners:
- Large ribosomal subunit protein mL44
- 39S ribosomal protein L40
- Large ribosomal subunit protein mL62
- Small ribosomal subunit protein mS25
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein mL65
- Small ribosomal subunit protein uS10m
- Large ribosomal subunit protein mL49
- Large ribosomal subunit protein bL32m
- Large ribosomal subunit protein mL45
Sequence:
MALRPRFWKCLSVCRKLECGFAALSTSSVPAVQPDVESKENEAVAPEFTNRNPRNLELLGVARKERGWATVWPNREFWHRLRVVKTQHHVEAFVEHLNGQVVVSASTREWAIKKHLYSTRNVVACESIGRVLAQRCLEAGINFMVYQPTPWEASSDSIKRLQNAMTESGVMLREPRRIYE
Protein: Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3) (Q13232)
Organism: Homo sapiens (Human)
Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:30587587, ECO:0000269|PubMed:37584589}; Peripheral membrane protein {ECO:0000269|PubMed:30587587, ECO:0000269|PubMed:37584589}. Cytoplasm {ECO:0000269|PubMed:26945015}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9WV85}.
Interaction partners:
- Nucleoside diphosphate kinase A
- Nucleoside diphosphate kinase B
- Nucleoside diphosphate kinase
- Inosine triphosphate pyrophosphatase
- Thymidylate kinase
- Adenylate kinase 9
- Guanosine-3',5'-bis
- Guanylate kinase
- Nucleoside diphosphate kinase, mitochondrial
- Cancer-related nucleoside-triphosphatase
Sequence:
MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE
Protein: Glutamate decarboxylase (Q8I4E0)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSSAAADESDAVLENLIAKEILPQTGNWEGTEEFLNRIVQVLLKYIKDQNDRDQKILEFHHPDKMQMLMDLSIPEKPESLLKLVKSCEDVLRLGVRTGHPRFFNQISCGLDLVSMAGEWLTATANTNMFTYEIAPVFILMEKSVMARMWEAVGWDPEKADGIFAPGGAIANLYAMNAARHQLWPRSKHLGMKDIPTLCCFTSEDSHYSIKSASAVLGIGADYCFNIPTDKNGKMIPEALEAKIIECKKEGLTPFFACCTAGSTVYGAFDPLERVANICERHKLWFHVDAAWGGGMLLSPEHRYKLAGIERANSVTWNPHKLMGALLQCSACLFRQDGLLFQCNQMSADYLFQQDKPYDVSFDTGDKAIQCGRHNDVFKLWLMWKSKGMEGYRQQINKLMDLANYFTRRIKETEGFELIIENVSFARIPEHLFLVRAFKDSKLGAC
Protein: Protocadherin 9 (F8VPK8)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNTSYIYDLIRRTMETPLDRNIGDSGQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQGIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSYSKNDNIPVTHQKCPGSTSFHIRENEESHSESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWIKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYGSNEGHFNNGGHMADIPLANLKSYKQAGGTIESPKEHQL
Protein: Probable amino-acid permease PB1C11.02 (Q9C0V0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000269|PubMed:10759889}; Multi-pass membrane protein {ECO:0000269|PubMed:10759889}.
Interaction partners:
Sequence:
MDASVSLLPEGESLHRSLSASQIQMLAFGGIIGTGLFLGIGSSLAESGPASLLISFSVLGVSVYCTMLALGEMSVYMPVAGSFCTYVGRYVDEALSFSLTWNYWLNDTIALASHVLATRLVVDFWLIPTEGDPVSASLSLPPWKEAVRIITPITSLSANIILNMLPVGGFGEIEYWLSSIKVFTVAAFIVNGILCNLGVNNEKKFIGFRYWKDPGAFNNGIIGVISSFVNAAFAYAGTESIALTAGEAKSPITTLPKAIRFTAHRVLLLYIISVLVVGINLPYNTPGLDGDSVRMSPFTFVFKKFGVPGAASIMNLVILSSALSAGNHSLYAGTRLLYSLAKSGHAPKVFSKCNKHGIPWLSVLATSATAILCLMSSQAGKTWGFLLNVIAVSNQISWIFIAVSSLRFRKALRVQGKTHRLYFPNWTYPVGPYIIILLNGVFLFLQGYKSLYPFRLSLFVSYYMEIPIVLGLYLIWKIYKKTKLVSSSEADLETDWKSLEDTDSA
Protein: RAN binding protein 3 (K7ESQ0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQ
Protein: Na(+)-translocating NADH-quinone reductase subunit B (Na(+)-NQR subunit B) (Na(+)-translocating NQR subunit B) (EC 7.2.1.1) (NQR complex subunit B) (NQR-1 subunit B) (A5F5X0)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00426, ECO:0000305}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00426}.
Interaction partners:
Sequence:
MGLKKFLEDIEHHFEPGGKHEKWFALYEAAATLFYTPGLVTKRSSHVRDSVDLKRIMIMVWLAVFPAMFWGMYNAGGQAIAALNHLYSGDQLAAIVAGNWHYWLTEMLGGTMSSDAGWGSKMLLGATYFLPIYATVFIVGGFWEVLFCMVRKHEVNEGFFVTSILFALIVPPTLPLWQAALGITFGVVVAKEVFGGTGRNFLNPALAGRAFLFFAYPAQISGDLVWTAADGYSGATALSQWAQGGAGALINNATGQTITWMDAFIGNIPGSIGEVSTLALMIGAAFIVYMGIASWRIIGGVMIGMILLSTLFNVIGSDTNAMFNMPWHWHLVLGGFAFGMFFMATDPVSASFTNSGKWAYGILIGVMCVLIRVVNPAYPEGMMLAILFANLFAPLFDHVVVERNIKRRLARYGKQ
Protein: Rca1p (Q5AB69)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Amino acid starvation-responsive transcription factor
Sequence:
MEELKDAREERSVCWASCRTSSSSVDDMTTPLFLHRKKIEGIFFFLSVSQLSLPAMNFPPFEQPLFDPNQAELLEEAERAKNSSIPFHNPFDVNSYPITNPPIFDSTMTVPYTTDGVPRRRRISISNGQIGQIVSHEAYFAEDLDVPPEFESRPQTSVIEPPPPPPPQPQPQLPVEIAGVPPPNHQLIYNNEVIYNPENGPIPGTAAWKKERLLERNRIAASKCRQRKKQEQVQIQNNIAKMEKELKKKDAKIAELEYTVELLKASIKSCIEDGNTDRLKQFI