wanglab/gogpt-training-data huggingface dataset:
Protein: Guanine nucleotide-binding protein subunit beta-5a (A1L271)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). Along with gnb5b, plays an important role in neuronal signaling, including in the parasympathetic, but not sympathetic, control of heart rate.
Subcellular location: Membrane {ECO:0000250|UniProtKB:P62881}.
Interaction partners:
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
- T-complex protein 1 subunit epsilon
- Adenylate cyclase-inhibiting G alpha protein
- Regulator of G-protein signaling 9
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein
- Si:ch73-167i17.6.
- Guanine nucleotide-binding protein G
Sequence:
MAAQEEPAQPGDSLATLKSESDTLKSKLEEERAKLHDVELHQVAEKIEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDAFTTNKEHAVTMPCTWVMACAYAPSGCAVACGGLDNKCSVYPLSLDKNENLAAKKKSVAMHTNYLSACCFTNSDMQILTSSGDGTCALWDVESGQMLQSFHGHAADVLCLDLAPSETGNTFVSGGCDKKACVWDMRTGQCVQSFESHDSDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFGGYNDYTINVWDVLKGARVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRIWA
Protein: Outer surface 22 kDa lipoprotein (Antigen IPLA7) (P0CL67)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Subcellular location: Cell outer membrane; Lipid-anchor.
Interaction partners:
- Neutrophil activating protein A
- Probable M18 family aminopeptidase 1
Sequence:
MYKNGFFKNYLSLFLIFLVIACTSKDSSNEYVEEQEAENSSKPDDSKIDEHTIGHVFHAMGVVHSKKDRKSLGKNIKVFYFSEEDGHFQTIPSKENAKLIVYFYDNVYAGEAPISISGKEAFIFVGITPDFKKIINSNLHGAKSDLIGTFKDLNIKNSKLEITVDENNSDAKTFLESVNYIIDGVEKISPMLTN
Protein: Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1) (Q9JM90)
Organism: Mus musculus (Mouse)
Function: May function as an adapter molecule downstream of KIT in the proliferation or differentiation of hematopoietic stem cells.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000305}. Mitochondrion {ECO:0000250}.
Interaction partners:
Sequence:
MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLVKRSDHQEYKHYWTELRGTTLFFYTDKKSTIYVGKLDIIDLVCLTGQHSTEKNCAKFTLVLPKEEVHVKTENTESGEEWRGFILTVTELTVPQHVSLLPGQVIRLHEVLEREKKRRIETDQLPLMPPEKEKEPVQDYADVLNPLPECFYAVSRKEATAMLEKNPSWGNMILRPGSDSKNYSITIRQEIEMPRIKHFKVTRTGNNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFIHSADDNFGQDPNIEDRSEKFKKNPHNA
Protein: t-SNARE affecting a late Golgi compartment protein 2 (Syntaxin TLG2) (Q08144)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: t-SNARE that functions in transport from the endosome to the late Golgi and on the endocytic pathway.
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Endosome membrane; Single-pass type IV membrane protein.
Interaction partners:
- Synaptobrevin homolog YKT6
- t-SNARE VTI1
- t-SNARE affecting a late Golgi compartment protein 1
- Vacuolar protein sorting-associated protein 45
- Synaptobrevin homolog 2
- Alpha-soluble NSF attachment protein
- Synaptobrevin homolog 1
- Protein SSO1
- Integral membrane protein SED5
- Vacuolar protein sorting-associated protein 54
Sequence:
MFRDRTNLFLSYRRTFPHNITFSSGKAPLGDDQDIEMGTYPMMNMSHDISARLTDERKNKHENHSDALPPIFIDIAQDVDDYLLEVRRLSEQLAKVYRKNSLPGFEDKSHDEALIEDLSFKVIQMLQKCYAVMKRLKTIYNSQFVDGKQLSREELIILDNLQKIYAEKIQTESNKFRVLQNNYLKFLNKDDLKPIRNKASAENTLLLDDEEEEAAREKREGLDIEDYSKRTLQRQQQLHDTSAEAYLRERDEEITQLARGVLEVSTIFREMQDLVVDQGTIVDRIDYNLENTVVELKSADKELNKATHYQKRTQKCKVILLLTLCVIALFFFVMLKPHGGGSGGRNNGSNKYNNDDNKTVNNSHDDGSNTHINDEESNLPSIVEVTESENDALDDLL
Protein: Paired box 6 (A0A1W2PQ31)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPD
Protein: receptor protein serine/threonine kinase (EC 2.7.11.30) (Q7JPN8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MESNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKELPAVPQNSVQTHPRYKCYSCEPPCRDPYEFTHTCQNAIQCWKLRTRDADGQVQESRGCSTSPDQLPMICSQNSLKINGPSKRNTGKFVNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSNSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASADEKIRLDFDEVCV
Protein: PA2394 (PvdN) (Q7B469)
Organism: Pseudomonas aeruginosa
Interaction partners:
Sequence:
MNDRRTFLKQAGILAAGLPLLSAAQSLRAEGVPSDAGNKWKALRQQFDLDPQYLHFANFLLTSHPRPVREAIERLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGTGVIIARSEQLQEHLVPSIPTFSRADNFGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNAYLKQRLGEHPKVRLVTPTSPELSSGFTFFRVEGRDCEAVAKHLMAHRVISDAVDRDVGPVVRLAPSLLNDEAEIDRVLEILAPQLA
Protein: Liprin-beta homolog (LAR-interacting protein beta) (Q94071)
Organism: Caenorhabditis elegans
Function: Involved in the regulation of synaptic function at neuromuscular junctions. Together with the liprin-alpha protein syd-2, may play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. Does not seem to be required for neuronal development. May regulate the disassembly of focal adhesions (By similarity). Does not bind receptor-like tyrosine phosphatases type 2A (By similarity).
Interaction partners:
- Liprin-alpha
- Tyrosine-protein phosphatase Lar-like
Sequence:
MVYSSSSMSNTNIRRRSVPITIQKSRMDGFAEANQLLSSALEQLDDIIRNGNSTSRSTTTIGSAGPTPIIKKSFRDLLPPPPALRSTFSPRIMENGHSNLAHKQHINDDIDNGNADDERSSREINRQWISTDWKHRTDLGSDGSSGVESPPSDLPTSSSSLFSPPRVYQEFVKAIDEQTMTERPDLETRLKIMQWVAGRTSPSPSMSTVSCPEYPELQDKLHRLAMARDSLQLQVSVLSEQVGAQKEKIKDLETVIALKRNNLTSTEELLQDKYHRIDECQELESKKMDLLAEVSSLKLRYATLEREKNETEKKLRLSQNEMDHVNQSMHGMVVQQQLAHHTNGHSSGGYMSPLREHRSEKNDDEMSQLRTAVQRLMADNEHKSLQINTLRNALDEQMRSRSQQEDFYASQRNYTDNFDVNAQIRRILMDEPSDSMSHSTSFPVSLSSTTSNGKGPRSTVQSSSSYNSSLSAVSPQHNWSSAGAGTPRQLHPIGGNQRVNNITSAQYCSPSPPAARQLAAELDELRRNGNEGANHNYSSASLPRGVGKASSTLTLPSKKLSVASGTSVGELGGSMSSVAQPTPKRNYRAQMNRWINEKLRRKRAVSAPNLVESDDEIARGRNLNNATSQSNLKNFSRERTRSSLRNIFSKLTRSTSQDQSNSFRRGSAARSTSTARLGSTNHLGTVSKRPPLSQFVDWRSEQLADWIAEIGYPQYMNEVSRHVRSGRHFLNMSMNEYEGVLNIKNPVHRKRVAILLRRIEEDIMEPANKWDVHQTLRWLDDIGLPQYKDVFAENVVDGPLLLSLTANDAVEMKVVNAHHYATLARSIQFLKKADFRFNAMEKLIDQNIVEKYPCPDVVVRWTHSATCEWLRKIDLAEFTQNLLFAGVPGALMIYEPSFTAESLAEILQMPPHKTLLRRHLTSHFNQLLGPKIIADKRDFLAAGNYPQISPTGRVKVVKKGFSLTRKKAKNEICLEPEELLCPQVLVHKYPTGAGDNSSFESSNV
Protein: Melittin (MEL) (MLT) (Allergen Api m 3) (Allergen Api m III) (allergen Api m 4) (P01501)
Organism: Apis mellifera (Honeybee)
Function: Melittin: Main toxin of bee venom with strong hemolytic activity and antimicrobial activity. It has enhancing effects on bee venom phospholipase A2 activity. This amphipathic toxin binds to negatively charged membrane surface and forms pore by inserting into lipid bilayers inducing the leakage of ions and molecules and the enhancement of permeability that ultimately leads to cell lysis. It acts as a voltage-gated pore with higher selectivity for anions over cations. The ion conductance has been shown to be voltage-dependent. Self-association of melittin in membranes is promoted by high ionic strength, but not by the presence of negatively charged lipids. In vivo, intradermal injection into healthy human volunteers produce sharp pain sensation and an inflammatory response. It produces pain by activating primary nociceptor cells directly and indirectly due to its ability to activate plasma membrane phospholipase A2 and its pore-forming activity.
Subcellular location: Secreted {ECO:0000269|PubMed:20403370, ECO:0000269|PubMed:20472009, ECO:0000269|PubMed:5592400}. Target cell membrane {ECO:0000269|PubMed:11509361, ECO:0000269|PubMed:456586, ECO:0000269|PubMed:6269667}. Note=Alpha-helical peptides form toroidal pores in the prey. {ECO:0000269|PubMed:11509361, ECO:0000269|PubMed:20403370, ECO:0000269|PubMed:20472009, ECO:0000269|PubMed:456586, ECO:0000269|PubMed:5592400, ECO:0000269|PubMed:6269667}.
Interaction partners:
- Apamin
- Hyaluronidase
- Hyaluronidase.
- Phospholipase A2
- Calmodulin-like protein 4
- Uncharacterized protein
- Uncharacterized protein
- Phospholipase A
Sequence:
MKFLVNVALVFMVVYISYIYAAPEPEPAPEPEAEADAEADPEAGIGAVLKVLTTGLPALISWIKRKRQQG
Protein: KIAA0100 protein (Q08E86)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVLKVDTSESLWHIQISRSRFLLDSDGKRLICEVSLCKINSKVLKSGQLEDTCLVELSLALDLCLKVGISSRHLTAITVDVWTLHAELHEGLFQSQLLCQGPSLASKPVPCSEVTENLVEPTLPGLFLLQQLPDQVKVKMENTSVVLSMNSQKRHLTWTLKLLQFLYHRDEDQLPLRSFTANSDMAQMSTELLLEDGLLLSQSRQRIVCLNSLKASVQVTTIDLSASLVLNTCIIHYRHQEFSHWLHLLALETQGSSSPVLKQRKKRTFPQILAPIIFSTSISNVNISIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEASDTCAQCLSRILSLMGPQSGKSAVSRHSSFGESVSLLWKVDLKVEDMNLFTLSALVGASEVRLDTLTILGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPETVPSLALETSGTTSELEGRAPEPLPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSFGSVSVEFPYQYDFSRTLDEAVGVQKWLKGLHQGTRAWASPSPVPLPPDLLLKVEHFSWVFLDDVFEVKLHDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPEHVVEQVQELDPGSPFPPEGLDLVIQWCRMLKCNVKSFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPLKFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGDLDINVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIKMDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVTQMVSDLSQVTVHLMASPTEENADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSARDGDPTFHTHQLHLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAKKPKRGVPTSASAPPRVNTPSFSGQPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVLENQEKEDLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRSVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGPGKGVAQGLTRSSGVRRSFRKSPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKSATGSEVRGKLETKSDLNMQQQEEEEKARLLIGLSVGDKNPGKKSIFGRRK
Protein: Programmed cell death 6 (A0A087WZ38)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000256|ARBA:ARBA00049643}.
Interaction partners:
Sequence:
MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV
Protein: glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (Q72C60)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Probable glycine dehydrogenase
- Glycine cleavage system H protein
- aminomethyltransferase
- Serine hydroxymethyltransferase
- 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase
- Threonine aldolase, low-specificity
- Aminotransferase, class V
- L-glutamate gamma-semialdehyde dehydrogenase
- Phosphoribosylformylglycinamidine synthase I
- Succinate--CoA ligase subunit alpha
Sequence:
MKTVFAKSVPGRSAALPSAPSRKAADMLPAGLLRSKAPRLPEVSELDVVRHFTGLSRLNYSVDGNFYPLGSCTMKYNPKFTEHVAALPGFTRLHPLMAQLKGAGQYTQGALEVMWETERLLCEINGMAAFTLHPMAGAHGELTGVMLIAAYHKDKGNRKTKIICPDSAHGTNPASAALAGYEVVNIESKDGLVDPDALEAVLDDEVAALMMTCPNTLGLFEKHLPRIVEKLRAVDALLYYDGANLNAIMGKMRVGDVGFDVVHLNLHKTFGTPHGGGGPGSGPVGVSARLEPYLPISRVEKERDGHFFLNYDYPKSIGYVAPFYGNFGVLLKAYAYILRLGAEGLTRASEFAVLNANYMRCKLRGVLDIPHDRTCMHEFVASACNTAECGVRALDIAKALLDKGYHAPTIYFPLIVKECLMFEPTETESRETLDAFMDDLASIVEQGRQTPDALHDAPLHTPVRRLDETAAARNMVLTDDL
Protein: alpha-1,3-glucan synthase (EC 2.4.1.183) (Q4WRQ8)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- chitin synthase
Sequence:
MFTETQRSVALILSLLSVSALCWPYTESLVDYNLNENRSAESPIDYWGEWPNHKYHPSPDNWRFPVYTIFLDRIANGDPTNDDINGTTFEHVLNSNQMRHGGDLVGLIDTLDYIRGMGFKGIYFAGTGLMNLPWAYDGYSPVDTTLLDMHHGTLEDWRRTITEIHNRDMYVIMDNTLATLSNLIGFKGHLNTSADFRPDEYEVEWITDRRYADFKFSNEYNKTCDYPKFWNETGFPLYSGGVEELKGCYNSDFDQYGELEAFGNFPDWKRQLTKFASVQDRLREWHKPVRDIITRHYCIQIASLDIDGFRYDKAVQATLEPLGEMSAAFRECAKKYGKHNFFLPGEITSGNTFGSLYLGRGRQPNQRPESAGAAVKLKNDSEAQYFLREDGYQALDAAAFHYTIYRSMTRFLGMDGNLVAGFDLPTDFIEAWNGMLVSNDFLNPLTGQLDPRHMYGVSNQDNFRWPAIINGTEKYLLGLFIVTLELPGIPLILWGEEQDMYVFDATATNYLFGRQPMTYQTAWWTHGCFNLNTTKFYNFPNERGLYGCHDITVTYDQRNPAHPLRNIMKRMFEIREHYPVANDGFYLQTLSQLTKDVYLPGSSNTPTVTGLWSVLRSYFPEVQPEASKGNNSIWLVYHNDNKTVTYGGDCKNRNTALLAPYKSGTKLKNVFAPYDELTLEDGPGDIEVHGTTESYGCARNMTLLPWEYRAYVEADRFVEPGPTVTEFVPGHDARLLSAEDTGETVDIQLGYSKEMDCTGVTRAISLNSTTEKGITPTLDTSSVNCGNITPRTSSHHYVGEVPTVWTWSAKLKNVHHGIHELTVKNVSTTSGVRTNAVDRFLFRMGTPTNPLITPLANYSTSLVHKSDDGSIYIQHEAAGADMFRYSTTFGRTWSNWTTYTGGNTTIEIAPFTGTDAQKWKGTHVRVQYFSRLTGSSDYIQEGDHDWEDGVPRRFPHLWWIGPYNQFGYDAGLDSKMRYDVKEGRWKYDFVYEWPSTGQISVWGVGPDGLPDPTEVYGDVDNASVVQKLPPSYLSSNVINITTPPPFPHLGWTISLNDANLRYEMTPVGSGWVQLVLFVLLWVVPILMGLAGAFIFMRTFYRVKLNTDGTAAKEDKLPLLWRKVRAQFTGADYSEMAISDKAVLPDSAIAGAAAGAPEHRRTVLIATMEYLIQDWKVKVKIGGLGVMAQLMSEHLRHQNLIWVVPCVGDIEYPEDTPAEPMMVTILDKPYLVNVQYHVVENITYVLLDAPVFRQQTKAEPYPPRMDDLDSAVYYSAWNQCIAETIKRFPSIDLYHINDFHGCLAPLYLLPTRTVPVCLSLHNAEFQGLWPLRTQQEKKEVCSVFNIPIETATKYCQFGNVFNLLHTGASYLRFHQRGFGAVGVSKKYGKRSWARYPIFWSLDKIGSLPNPDPSDTGAVGDGAETNVSIPSPEDRIRDKLQAQKWAGLKEDPNADLLVFVGRWSKQKGVDLIADVMPAILSARPHVQLICVGPIIDLYGKLAAIKLERIMAMFPGRVFSKPEFTILPPYVFSGANFALIPSRDEPFGLVAVEFGRKGALGIGSRIGGLGQMPGWWYTVESDATRHLLHQLRTAIKSALDSDQETREEMRMNSAKQRFPVLEWIQKLETLQQTAIQIHHTKNKNTVAGPMPEPQIYWEMQNMRDSTASLPGLAQSVPDGLETPPSRVMLNAESRLRELQTDVGNRSSLGRKLSLGRRAGPGQGRNRLVKKALRDSQVAESPLDEEATDAEGEVDEDDSNSHRVDYISTDEAMRAVSHALGLQDNGESVGNGNGNGNNSVTPPYHSMPGSPYLVSRASSPVPRTPSDMPQYPFQFALNSGEGMPFAHSRNVSVLSLPSVMGDHNQQVFELQKVDPTFTDSMGHFTRRFEQLLNNLDKKNSMTDCCIETYLMKSERKFYNMYNDAQLKKHHAKESISSSASPEQLDHETQYNRLSTATAGSDPSDSDEIDRWLSRLGYRRPVAIQRFMRRRIGTWPVYALFLGLGQIIATNSAQITLLVGQVGETATKLYVIAAIYCVSSISWWFMYARLPAVIVLSLPWFIYCLAFIVIGVSPFGLSEVGRGWAQNVAAGVYAVASSSGSLFFALNFGDQGAVPVKDWMFRASLIQGISQLYTVALWYWSSKVTATEIGGVSTFALSTWRLTAVVMPIAALCFAIGVILALGLPKYYRQAPSRILFFYTSLFRRRIVLWFFLMVIVQNWFLAAAFGRNWSFLWSSKHAKTWEVVILVVGFFIIIWVLILFAFRALSKEHSWILPVFGLSLGSPRWAQTWWGTSNIGYYLPWAGGLTSGAIVSRCLWLWLGVLDEIQQVGLGMILLQTLTRVHVCFVLLAAQAVGSVATICARGFAPNRLGPDGISPNIGTSVDKIANAWFWIALFFQLLASFGFLLFYRKEQLNRP
Protein: Slr2060 protein (P73812)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- Sll1752 protein
- Uncharacterized protein ssl0461
- Slr0397 protein
Sequence:
MESPIQAQPPLDFLAPNLQPWLLRLGPLILPWWIRSQTAIAKIEAENLQVLAQAYGDFSQGKNRLLLAFRHPSINDPLCMGYLFWNLLPPALKKGALQPPPVSHSHFMYDRGIPLWGGDFLQWLFPRLGGTSIQRGKLDRPGLRSARDLMLNGQYPLAAAPEGATNGHNELISPLEPGIAQLGFWCAEDLRKAQRPEQTLILPVGIQYFYLTPPWREIENLLSQLENDCGIGPTTDHSLGEARLYERLYSLGEVMLDLMENFYRQFYQQNLPAVEDLAQSLQENFNNLETDPNQLLASRLQNLLHAALTVGEEYFQITPKGTLPDRCRRLEQAGWDCIYREDLRDEQTLFPVKKGLADRIAEEADLRMWHMRLVENFVAVTGHYVKEKPTVERFADTLLLLWNVITRMKGGNLNNRPILGRQRVQLTIGEPILVDDHYEDYKGNRKLAIAKVTEVLQEKLSALII
Protein: Cuticular protein 49Ac, isoform A (LP07813p) (Q960H8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFTKSMLSFSLVVALFVVCHASPVPDNNGRSGSQESIGRYHHMPIPYRHVSDQRELGKYHHIPYPYDGGYGPYAGSNIPYVHDDRPYNHDLYTSTTTKKPTTTTKRTTTSTTTTTTTPRNILFNYDDEGRHKILHKEEVRKQDKYDHSYLTENGIYGEEQAKLHHTGGTHAKGFYEYTGDDGKLYRVNYASNDGGFMPQGDHIHPIPDAIVRALKYVEEQHKINGGAQFDHRGFRINHMTKDLKAQIKAIHLEEMPKELTEQIHMLEHEVELAEEEEREEQAALERLRQAAKSH
Protein: ScaB cellulosomal scaffoldin protein (Q9AE52)
Organism: Ruminococcus flavefaciens
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKKLLSAVTSVAMSFTLMAGAFASSVSAAGGLSAVQPNVSLGEVLDVSANRTAADGTVEWLIPTVTAAPGQTVTMPVVVKSSSLAVAGAQFKIQAATGVRYSSKTDGDAYGSGIVYNNSKYAFGQGAGRGIVAADDSVVLTLAYTVPADCAEGTYDVKWSDAFVSDTDGQNITSKVTLTDGAIIVKKDNNTGKIKWVLDKVTAAPGETVTVKATVDASGEGTVAVAGAQFDVNADSPIVYDSAKEGGAYITSLTVNDAKHKFAFGRTTGTGIVAADKATVAAFTYKVPSDCTEGTYDVKWSGGFVSDADGKDITSRVTFVDGSITVKNDVQTVGKWVLDNVTAAQGETVTLKAVVDDSAKAAVPVAGAQFKLQAADAVKYSSFTDGTAYGAAFTKNDDKQSFAFGNTGGKGVAAADKAAIYTVSYTVPTDCPDGTYPVKWADTFVSDTDGRNITSNIIFVDGSITVGKPVTGTVEWVIPKVDADAGDNVTLQVAVKGDADLPVSAAQFDVNGATPLNYQESAGKPYGVDLVVNDTKQHFAFAQASGISKTAKDGDKLFTITFKVPEDCADGIYPVTWAKQFVSDENGNNITDKVTFTDGWVRVGNPPTTTTTTTTSVTTTTTTTTVTAPKGGIIWAIDTVTVEPGQTATLNIKVVDEDNSKLPIAGAQFNIVNKDGVNYSSIAGSEAYGPTITANDAKKKFDFANASGVETVGANNANVAVLTYTVPATAEEGVYPVQFAEGSLKIFDKDGKDISDKIIGVDGAIIVKKPVVTDVTSTTTVTSNVNTTTSTTTVTAPQGGIIWAIDTVTVEPGQTATLNIKVVDLDNSQLPIAGAQFNIVNKDGVNYSSIAGSEAYGPKITANDAKKKFDFANASGVETVGANDAIVAVLTYTVPATAEEGVYPVQFAEGSLKIFDKDGKDISDKIIGVDGAIIVKKPVITETSTTTTVTGKPNTSTTTTTGTDVTTSGNETTDTTVTTVTTTDVTGPTTTSTDTTVTSSVVGPTTTSTIVTDTTVTSSVIGPTTTTTVVTDTTVTSSVIGPTTTTTVVTDTTVTSSVIGPTTTTTVVTDTTVTSSVIGPTTTTTVVTDTTVTSSVIGPTTTSTTVTTEVTGPTDTTATSTGTSTTDVTGPTDTTVTSTGTSTTDVTGPTDTTVTSTGTSTTDVTGPTDTTVTSTSTTTDVTGPTDTTVTDTTVTTVVTNPTTTLTTTTIVVPKDSIAWVVDTVAAYPGDEVTLKITVKDPNAANLGIAGAQFKVTPDGDVQLVKSGDKSGYGADIIPSKDGYKFVFADGAGVAHVAPDGTVVIELTYKVGEEVAPGTVIPVSIKDLYVVDEDGNDITKYVMPVDGSIIVFEKPAPTSTTTNVTVTTVTTDVTGPTDTTVTSTGTSTTDVTGPTDTTVTSTGTSTTDVTGPTDTTVTSTSTTTDVTGPTDTTVTSTSTTTDVTGPTDTTVTSTSTTTDVTGPTDTTETSTSTTTDVTGPTTTSTTSTSTETTSTDTTTSTSTSSTSTTSTTDANYDHSYAVIETQVGYYFSHDDGVRANGQVGGFNKGQVVTLKIVDVYKDGSEVERPEVNMDLINFNNNTPEKAYNSRTHINKQTTITDFKYDIPVYYGDMPLVDKSGKALTVTAYIGVKGDITLSNMVDSNDASVALSYYTLISTGSNTPANTICQITEEGLQVSSALDELDNLAAFLGDVNTNEWDPDNWKTTKMGRKIDSNDASQILAFYSKRTSHVYDDVSSNDIWNEILGDARFGK
Protein: Dynein light chain Tctex-type 3 (Q5XI90)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Dynein light chain 2, cytoplasmic
- Cytoplasmic dynein 1 intermediate chain 1
- Dynein light chain roadblock
- Dynein light chain roadblock-type 1
- Dynein light chain 1, cytoplasmic
- Cytoplasmic dynein 1 light intermediate chain 1
- Dynein light chain Tctex-type 2B
- Cytoplasmic dynein 1 heavy chain 1
- Dynactin subunit 1
- Cytoplasmic dynein 1 intermediate chain 2
Sequence:
MDGYQRPCDEIGFNAEEAHNIVKECVEGVLGGNDYNQNSINQWTASIVEQSIAHLVKLGKAYKYIVTCAVVQRSPYGFHVASSCFWDTTSDGTCTVRWENRTMNCVVNVFAVAIVL
Protein: Claudin (Q7YS66)
Organism: Sus scrofa (Pig)
Subcellular location: Cell junction, tight junction {ECO:0000256|RuleBase:RU060637}. Cell membrane {ECO:0000256|RuleBase:RU060637}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU060637}.
Interaction partners:
Sequence:
VTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVGAVLLALVALFVTLAGAQCTTCVAPGPGKARVALTGGALYALCGLLALVPLCWFANIVVREFYDPTVPMSQKYELGAALYIGWAASALLMCGGKP
Protein: Signal transducer and transcription activator (d-STAT) (Protein marelle) (Q24151)
Organism: Drosophila melanogaster (Fruit fly)
Function: Might play a role in signal transduction and activation of transcription. Plays an important role in the segmental pattern formation in the early embryo by activating specific stripes of pair rule gene expression in early development as part of the Janus kinase-STAT pathway. Might play a role in male germline stem cell maintenance.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocated into the nucleus in response to phosphorylation. {ECO:0000250}.
Interaction partners:
- Tyrosine-protein kinase hopscotch
- Cytokine receptor
- Suppressor of variegation 2-10, isoform I
- Outstretched
- FI03911p
- Suppressor of cytokine signaling at 36E, isoform D
- Transcription factor Jra
- Histone deacetylase HDAC1
- Tyrosine-protein phosphatase non-receptor type 61F
- Heterochromatin protein 1
Sequence:
MSLWKRISSHVDCEQRMAAYYEEKGMLELRLCLAPWIEDRIMSEQITPNTTDQLERVALKFNEDLQQKLLSTRTASDQALKFRVVELCALIQRISAVELYTHLRSGLQKELQLVTEKSVAATAGQSMPLNPYNMNNTPMVTGYMVDPSDLLAVSNSCNPPVVQGIGPIHNVQNTGIASPALGMVTPKVELYEVQHQIMQSLNEFGNCANALKLLAQNYSYMLNSTSSPNAEAAYRSLIDEKAAIVLTMRRSFMYYESLHEMVIHELKNWRHQQAQAGNGAPFNEGSLDDIQRCFEMLESFIAHMLAAVKELMRVRLVTEEPELTHLLEQVQNAQKNLVCSAFIVDKQPPQVMKTNTRFAASVRWLIGSQLGIHNNPPTVECIIMSEIQSQRFVTRNTQMDNSSLSGQSSGEIQNASSTMEYQQNNHVFSASFRNMQLKKIKRAEKKGTESVMDEKFALFFYTTTTVNDFQIRVWTLSLPVVVIVHGNQEPQSWATITWDNAFAEIVRDPFMITDRVTWAQLSVALNIKFGSCTGRSLTIDNLDFLYEKLQREERSEYITWNQFCKEPMPDRSFTFWEWFFAIMKLTKDHMLGMWKAGCIMGFINKTKAQTDLLRSVYGIGTFLLRFSDSELGGVTIAYVNENGLVTMLAPWTARDFQVLNLADRIRDLDVLCWLHPSDRNASPVKRDVAFGEFYSKRQEPEPLVLDPVTGYVKSTLHVHVCRNGENGSTSGTPHHAQESMQLGNGDFGMADFDTITNFENF
Protein: Metabotropic glutamate receptor 3 (mGluR3) (Q14832)
Organism: Homo sapiens (Human)
Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:8840013}; Multi-pass membrane protein {ECO:0000269|PubMed:8840013}.
Interaction partners:
- Metabotropic glutamate receptor 2
- Glutamate receptor ionotropic, NMDA 2A
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Glutamate receptor ionotropic, NMDA 2B
- Glutamate receptor 1
- Adenylate cyclase type 8
- Glutamate receptor 4
- Calcium/calmodulin-dependent protein kinase type II subunit gamma
Sequence:
MKMLTRLQVLTLALFSKGFLLSLGDHNFLRREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNHRRVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLADEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNVVTHRLHLNRFSVSGTGTTYSQSSASTYVPTVCNGREVLDSTTSSL
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (Q5ZIM8)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MSAKEGSKVLLLPPHATSERAVKAVPFPPTHRLTSEEVFDTDGKPRVDILKNHLIKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMEAFDCLPLAALLNQQFLCVHGGLSPEINTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNESSPEHFSHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGTAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSAIRGFSPQHKICSFEEAKGLDRINERMPPRKDALQQDGINTINTTNANGNNGTGNNNAQ