wanglab/gogpt-training-data huggingface dataset:
Protein: Staphylokinase (Q99SU7)
Organism: Staphylococcus aureus (strain N315)
Function: Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules (By similarity).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDSKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVIEKK
Protein: Pyruvate decarboxylase (EC 4.1.1.1) (Q4WXX9)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- alcohol dehydrogenase
- Aldehyde dehydrogenase
- alcohol dehydrogenase
- Aldehyde dehydrogenase
- aldehyde dehydrogenase
- Lactate dehydrogenase
- Aldehyde dehydrogenase, putative
- Pyruvate kinase
- pyruvate, water dikinase
- Alcohol dehydrogenase, putative
Sequence:
MATDIATRELRKPVDVAEYLFRRLHEVGIRSVHGVPGDYNLAALDYLPKCGLHWVGNCNELNAGYAADGYARVNGISALITTFGVGELSAINAIAGAYSEFVPIVHIVGQPHTRSQRDGMLLHHTLGNGDYNVFARMNAGVSTTVGRLNDTHEVATLIDNAIRECWIRSRPVYITLPTDMVTKKIEGERLNTPIDLSLPANDPEKEDYVVDVVLKYLHAAQRPVILVDACAIRHKVLQEVHDLMEASGLPTFVAPMGKGAVDETHKNYGGVYAGDGSNTGVREQVESSDLILSIGAIKSDFNTAGFTYRIGQLNTIDFHSTYVRVRYSEYPDINMKGVLRKVIQKLGRVNAQPVPHLSNNLPDDEPKSGDQPITHRWFWPKIGQWLKENDIVITETGTANFGIWETRFPAGVTAISQVLWGSIGYSVGACQGAALAAKEQGNRRTILFVGDGSIQLTLQEISTMIRNKLNPIIFVICNEGYTIERYIHGWEASYNDIQQWDYKSLPVAFGAGKDYKGYRVKTKDDMIKLFENTEFASAPFLQLVELYMPREDAPSALKLTAEAAASRNK
Protein: Histone acetyltransferase (EC 2.3.1.48) (Q9VM15)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU361211}.
Interaction partners:
- Double parked, isoform A
- Protein MBD-R2
- Inhibitor of growth protein 5
- histone acetyltransferase
- Chromatin modification-related protein MEAF6
- Transcription-associated protein 1
- Cell division control protein
- Enhancer of polycomb-like protein
- Bromodomain-containing protein homolog
- DNA methyltransferase 1-associated protein 1
Sequence:
MALESGSSSSESGSSSTSGSTSSETGSSSDTDSSSATPEEKPSTNSSAKSQTQTQQQTNSGNAQRRKPVPAASEDKPKPSVAPSSKKVNNPPKSKLSSDDDEYEDSAPPAKKNSRAMGSSTVTAAAAASAARRKPPASVNKPSNPANKPSNPTQRSANNNTNRSLENGEGKRPSLSSSSNSTDDSMKIVKNGRKVPLKMASTVRPKQIRGKLPPAKKNGGGPVISSDGSSGSESGSNSGDESSSGSESEGSDSSNSYSSQPVKGGAKGKRSGPTKIQNSDSEEERKDKANPMRKLTRSLSMRRTKQQPKQETDSESDGDLEDDKIMISKSPAKKPAPSNLNASKSKVKREPIGISSGVLSSIKSRPVSPITQTEKKCPIEGCDSSGHLSGNLDKHFLPEACPIYHNMSASECKERANERKLRNEQRLKMPVNIVTAPGNQNTNLKTLSPEQREFLAKIRESRANFKPANNNFLDSKVKLEKDVTDEDREPNLAGLVPDYDLQLFREAQAQASERIEDELKDLPVGKGIKYISMGKYKMKVWYQSPYPDDAARLPKMYICEFCLRYQKSETGIKRHAEKCVWRHPPGDEIYRKGKLQVWQVDGKRYKQYCQHLCLLAKFFLDHKTLYYDVEPFLFYIMTLADVDGCHIVGYFSKHIPFLQEKNSFYNVSCILTLPPYQRKGYGRLLIDFSYLLTRVEGKIGSPEKPLSDLGLISYRSYWKDVLLDYLCNRSGNTIAIKDVSQETAIYSYDIVSTLQALGMMKYWKGKHIVLKKQDVLDEYEERVKRRGTFPKIDDSCLRWQPFINIQPSSSP
Protein: DNA ligase B (EC 6.5.1.2) (Polydeoxyribonucleotide synthase [NAD(+)] B) (P25772)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
Interaction partners:
- DNA ligase])
- Ribosomal RNA small subunit methyltransferase B
Sequence:
MKVWMAILIGILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRKMVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVTDGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWLGAKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP
Protein: Dephospho-CoA kinase domain-containing protein (Q8WVC6)
Organism: Homo sapiens (Human)
Interaction partners:
- Bifunctional coenzyme A synthase
- Adenylosuccinate lyase
- Ribonucleoside-diphosphate reductase large subunit
- V-type proton ATPase subunit F
- Endonuclease 8-like 3
Sequence:
MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEVLLENGDINRKVLGDLIFNQPDRRQLLNAITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMRRNSLNRKDAEARINAQLPLTDKARMARHVLDNSGEWSVTKRQVILLHTELERSLEYLPLRFGVLTGLAAIASLLYLLTHYLLPYA
Protein: Solute carrier family 2, facilitated glucose transporter member 3 (GLUT-3) (Glucose transporter type 3) (F1NTJ1)
Organism: Gallus gallus (Chicken)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU368110}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU368110}. Cell projection {ECO:0000256|ARBA:ARBA00004316, ECO:0000256|RuleBase:RU368110}. Perikaryon {ECO:0000256|ARBA:ARBA00004484, ECO:0000256|RuleBase:RU368110}.
Interaction partners:
Sequence:
MADKKKITASLIYAVSVAAIGSLQFGYNTGVINAPEKIIQAFYNRTLSQRSGETISPELLTSLWSLSVAIFSVGGMIGSFSVSLFVNRFGRRNSMLLVNVLAFAGGALMALSKIAKAVEMLIIGRFIIGLFCGLCTGFVPMYISEVSPTSLRGAFGTLNQLGIVVGILVAQIFGLEGIMGTEALWPLLLGFTIVPAVLQCVALLFCPESPRFLLINKMEEEKAQTVLQKLRGTQDVSQDISEMKEESAKMSQEKKATVLELFRSPNYRQPIIISITLQLSQQLSGINAVFYYSTGIFERAGITQPVYATIGAGVVNTVFTVVSLFLVERAGRRTLHLVGLGGMAVCAAVMTIALALKEKWIRYISIVATFGFVALFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMLFPYAEKLCGPYVFLIFLVFLLIFFIFTYFKVPETKGRTFEDISRGFEEQVETSSPSSPPIEKNPMVEMNSIEPDKEVA
Protein: ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) (H7BXY3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000256|ARBA:ARBA00004436}.
Interaction partners:
Sequence:
MCVNPTPGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPLRDSRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLRGPCGSFDVRKTADD
Protein: Bifunctional purine biosynthesis protein ade10 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)] (O74928)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR). Also catalyzes the cyclization of FAICAR to IMP.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P54113}.
Interaction partners:
- Phosphoribosylglycinamide formyltransferase
- Adenylosuccinate synthetase
- C-1-tetrahydrofolate synthase, mitochondrial
- Adenylosuccinate lyase
- Inosine-5'-monophosphate dehydrogenase
- C-1-tetrahydrofolate synthase, cytoplasmic
- Bifunctional purine biosynthetic protein ADE1
- Probable serine hydroxymethyltransferase, cytosolic
- Serine hydroxymethyltransferase, mitochondrial
- Adenine phosphoribosyltransferase
Sequence:
MYALLSVYDKTGLLELAKALTSKGVKLLGSGGTAKMIRESGMEVADVSSITNAPEILGGRVKTLHPAVHGGILARDIPSDEKDLVEQSIEKIDIVVCNLYPFRETIAKPNVTIPEAVEEIDIGGVTLLRAAAKNHARVTILSDPADYATFTDKFLSDKLTQDDRNTYALKAFASTASYDAAITDYFRKQYAAGVDQLTLRYGANPHQSPAQAFMEQGPLPFKVLCGSPGYINLMDALNSWPLVKELRENIGIPAAASFKHVSPAGAAVGLPLSDVEKKVYFVSDITEFTPLACAYARARGADRMSSFGDFIALSDTVDVCTARIISREVSDGVIAPGYEPEALELLKKKKGGKYCVLQMDPKYVPAEIETRQVYGISLQQHRNHAKIDFSLFEKVVSKNKDLPKSALIDLVIATTALKYTQSNSVCYAKNGMVVGLGAGQQSRIHCNRLAGDKADNWWLRHHPKVLGMQFKKSAKRPEKSNAIDLYVLDAVPAEGSEREQWESAFETIPEPLTKKEREEFLATCKDVVCASDAFFPFPDNIYRLAQSGVKYVAAPGGSVMDQAVRDTANEFNMVFSEIPLRLFHH
Protein: Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Suppressor of K(+) transport growth defect 2) (Protein SKD2) (Vesicular-fusion protein NSF) (P46460)
Organism: Mus musculus (Mouse)
Function: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack GRIA2 leads to influence GRIA2 membrane cycling (By similarity).
Subcellular location: Cytoplasm.
Interaction partners:
- Alpha-soluble NSF attachment protein
- Beta-soluble NSF attachment protein
- Synaptosomal-associated protein 25
- Sec1 family domain-containing protein 1
- Gamma-aminobutyric acid receptor subunit gamma-2
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit beta-3
- Gamma-aminobutyric acid receptor subunit beta-1
- Glutamate receptor 2
- Gamma-aminobutyric acid receptor subunit alpha-4
Sequence:
MAGRTMQAARCPTDELSLSNCAVVNEKDFQSGQHVMVRTSPNHKYIFTLRTHPSVVPGCIAFSLPQRKWAGLSIGQDIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALMREEGASPLDFD
Protein: Orthodenticle homolog 5 (Q6NYT9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MMSYMKQPHYSVNGLTLTGTGMDLLHSAVGYPNTPRKQRRERTTFTRAQLDVLEALFSKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQTSGQTKPRPPKKKSSPARDSSASEPSASTSGPYSPPPPPPGTAITPSSSSATVSIWSPASISPLPDPLSAPSTACLQRSSYPMTYSQAPAYGQSYAASSSYFTGLDCSSYLSPMHPQLSASGGALSPMSGALSQSPASLSSQGYTAASLGFGTVDCLDYKDQTSAWKLNFNAADCLDYKDQNSWKFQVL
Protein: Nuclear distribution protein nudF (Lissencephaly-1 homolog) (LIS-1) (Nuclear migration protein nudF) (Q00664)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip, and this requires clipA and nudE. Localizes to the mitotic spindle poles, specifically to the spindle pole bodies (SPBs).
Interaction partners:
- Dynein heavy chain, cytoplasmic
- Nuclear distribution protein nudE
- Nuclear movement protein nudC
- Dynein light chain, cytoplasmic
- Cytoplasmic dynein intermediate chain
- Lysophospholipase
- Putative phospholipase
- Putative phospholipase
- MBOAT family protein, putative
- Patatin-like phospholipase domain-containing protein
Sequence:
MSQILTAPQAEALHKAMLAYLSVINAPQTAETLREELHFDESYNEATCKKFEGVLEKKWTGIARLQRRINDLEAEVRSLQAELEASPSAARAKNQDPTNWLPKPSSTHTLTSHRDAVTCVAFHPVFTSLASGSEDCTIKIWDWELGEIERTLKGHIRGVSGLDYGGQKGNTLLASCSSDLTIKLWDPSKDYANIRTLSGHDHSVSSVRFLTSNDNHLISASRDGTLRIWDVSTGFCVKVIKSATESWIRDVSPSFDGKWLVSGGRDQAITVWEVSSAEPKAALLGHENFIECCVFAPPASYEHLATLAGLKKPPPATSSCEFVATGARDKTIKLWEARGRLIKTLHGHDNWVRGLVFHPGGKYLFSVSDDKTIRCWDLSQEGRLVKTISGAHEHFVSCIRWAPSPNTDNPDPAGEKAGKKDAVKPSYRCVIATGCADNSVRVFS
Protein: XK-related protein (B7ZMN2)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}.
Interaction partners:
Sequence:
METVFEEMDEESTGGVSSSKEEIVLGQRLHLSFPFSIIFSTVLYCGEVAFGLYMFEIYRKANDTFWMSFTISFIIVGAILDQIILMFFNKDLRRNKAALLFWHILLLGPIVRCLHTIRNYHKWLKNLKQEKEETQVSITKRNTMLEREIAFSIRDNFMQQKAFKYMSVIQAFLGSVPQLILQMYISLTIREWPLNRALLMTFSLLSVTYGAIRCNILAIQISNDDTTIKLPPIEFFCVVMWRFLEVISRVVTLALFIASLKLKSLPVLLIIYFVSLLAPWLEFWKSGAHLPGNKENNSNMVGTVLMLFLITLLYAAINFSCWSAVKLQLSDDKIIDGRQRWGHRILHYSFQFLENVIMILVFRFFGGKTLLNCCDSLIAVQLIISYLLATGFMLLFYQYLYPWQSGKVLPGRTENQPEAPYYYVNIEKTEKNKNKQLRNYCNSCNRVGYFSIRKSMTCS
Protein: Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (P11980)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the final rate-limiting step of glycolysis by mediating the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Subcellular location: [Isoform M2]: Cytoplasm {ECO:0000250|UniProtKB:P14618}. Nucleus {ECO:0000250|UniProtKB:P14618}. Note=Translocates to the nucleus in response to various signals, such as EGF receptor activation or apoptotic stimuli. {ECO:0000250|UniProtKB:P14618}.; SUBCELLULAR LOCATION: [Isoform M1]: Cytoplasm {ECO:0000250|UniProtKB:P14618}.
Interaction partners:
- Alpha-enolase
- L-lactate dehydrogenase A chain
- Fructose-bisphosphate aldolase A
- Glucose-6-phosphate isomerase
- L-lactate dehydrogenase B chain
- Beta-enolase
- Hypoxia-inducible factor 1-alpha
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Enolase 4
- Gamma-enolase
Sequence:
MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
Protein: Son of sevenless homolog 2 (F1R019)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Growth factor receptor-bound protein 2
- Growth factor receptor-bound protein 2a
- Epidermal growth factor receptor precursor.
- GTPase NRas
- small monomeric GTPase
- HRas proto-oncogene, GTPase a.
- RAS-related
- RAS-related 2
- Muscle RAS oncogene homolog
- Ras-related protein M-Ras
Sequence:
MQHDFSSSEENSARWRGLFVQGLRKVQVQVHPNLSAKEDALQHIEALILQLLNKLCVTQPRTIADVEDRVQKTFPNPIDKWAMGDAQNAIEKRKRRNPLLLPVDKIHPLLKEVLGYKIDYNVCLYIVAVLEYISADILKLAGNYVSNIRHYEISQQDITVSMCADKVLMDMFDQEEEMGLLSQSVEEVSSSGVLTYDDLVRLEIAEERQYLRELDLIIKVFRQAFMSNSKLFSAQDVELAFSNILEVQELTVKLLGLIEDAVEMTADGSPHPLVGSCFEDLAEEQAFDPYETLSQDILSKEFCQHFNTLMSRPTVALHFQSIAEGFKEAVQYVLPQLMMVPVYHCIHYFELLQQLQECSEEQDDRECLKQAQTALINLQCSIERIYAKHQPRRKQGEPLYRLYSRASRSKQAAIKRMNDIQKSIDGWEGKDIGQCCSQFILEGALLRAGAKHERHNFLFDGLMISCKANQSSRLPGAGSGAEFRLKEKFVLRKYRIVDREDSPEFRHAFELVGREESGAVFSARSAEEKSAWMAALVTLQYRPTLDRMLDTVLHREEQAQPLRLPSPDVYRFAIQDSEENIVFEEGAQSKTGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQDLLTLLIERIEIPEPEPSEADREALWNGEQPMAAELQRFRREYVQPVQLRVLNVFRQWVEHHFYDFENDPELYERLEGYLISTTQLRGKSMRKWVESISKIMRRKIQMQSNGISHNITFESPPPPIEWHISRPGQVDTFDLMTLHPIEIARQLTLLESDLYRAVRPSELVGSVWTKEDKEKNSPNLLRMIRHTTNLTLWFEKCIVEAENVDERVAVFSRIIEILQVFQELNNFNGVLEIVSAINSVPVYRLDHTFEAVPERKRRILEEAVELSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNPDFLKRDGKELINFSKRRKVAEITGEIQQYQNQPYCLKVEHDIKRFFENLNPMGNMNEKDFSDYLFNKSLEIEPRNSKQPPRFPRKTTYSLKSPGVRPVRQAVGGGGTLKGHPVPLEREPPHKITFRSIAETEPETPPSLPTSPNTPTPPQSASSDFNSVFEQDFMPYGNNTIFAPVFLPQSKFQSVSCGSLHQLMSDEPLKPPPLPPRRKDTSSDKNSRSDSPPAIPPRLPPPPRLQPRVPVINGPTDGPLPSPPPPLPRDPLPDTPPPVPQRPPEIFINYPVNMQPSPGGRFHWDFTTSPSTPNTPPGTPSPRAVLPGTPSPRVPRRPCTPSVSQPILVHLPPPTPAPPIPPRHNSTSALPKLPPKTYKRELSQSSHTLSQPSLHTLSLVDNRDSNE
Protein: Protein CANDIDATE G-PROTEIN COUPLED RECEPTOR 2 (AtCand2) (Protein PHYTOMELATONIN RECEPTOR 1) (Q94AH1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in plants and microbes interactions. G-protein coupled receptor involved in root growth mediated by the bacterial quorum-sensing signals N-acyl-homoserine lactones (AHLs). Binds to melatonin. Phytomelatonin receptor required, in collaboration with GPA1, for melatonin-mediated stomatal closure involving H(2)O(2) and Ca(2+) signals.
Subcellular location: Cell membrane {ECO:0000269|PubMed:29702752}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein CANDIDATE G-PROTEIN COUPLED RECEPTOR 7
- Acetylserotonin O-methyltransferase
- Protein CANDIDATE G-PROTEIN COUPLED RECEPTOR 6
- Guanine nucleotide-binding protein alpha-1 subunit
- LanC-like protein GCR2
- AT3g59090/F17J16_140
- Heptahelical transmembrane protein 5
Sequence:
MRVLSEIAESPFVISRLSPDSTATGGFIGGWVGKCHGFLHNTVLVLASILFVAYLAYEAKKSLSKLSNRRSYIMIAYYGFLWLVSLLNLAWCCLQAWECTPGKEVIWNLLTLFTTSGMLFLEVSLVAFLFQGNYASGAEALTRTFLISGLVIGLDLLLKAIYLFGFGVPLFIDNNEHIHKFKWGLWVIHKLLLAGIYGMIFFMYNSKWRERLPARPAFYKYITVMLALNGLSLFACALTANGAHFGLWLYGITSVCYHAFYLPLLYVTFLADFFQEEDLNLENVYYSEMKDAGFFDADWE
Protein: Proteasome subunit beta (O17312)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU004203}. Nucleus {ECO:0000256|RuleBase:RU004203}.
Interaction partners:
Sequence:
MDLDNARELPRAGFNFDNCKRNATLLNRGFKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRYQGHISAALVLGGVDKTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDADPTGVFNDLGSGSNIDLCVIRKGSVEYLRNYELANKKGKRQLDYRFKTGTSTVLHTNIKDLLVTERVQAVPMEIS
Protein: Tubulin--tyrosine ligase-like protein 5 (Q9VBX5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- LD38689p
- Spastin
Sequence:
MPSSLCEALTNSSISFDYQKEDDWITSGKLGSREAVLVFRTNILNPKIRKTLSEKSSAQVLTDTKDNEEKPVQSPQKLAEEEPTSSEPSSKEALSGSTQQKIFLLKKPQQCDKSDKLTFSSPFKKILNRYSSSDTSISSEGEEPANSSENKSRVLKTSQNAINIKLATDLSNESGYESIAPAKTISNTEVIEEDQEETSEDDAECGINMPASKLKITYKFHQTETKLLRKLFNVHGLTEVQGENNNFNLLWTGVHMKLDIVRNLAPYQRVNHFPRSYEMTRKDRLYKNIERMQHLRGMKHFDIVPQTFVLPIESRDLVVAHNKHRGPWIVKPAASSRGRGIFIVNSPDQIPQDEQAVVSKYIVDPLCIDGHKCDLRVYVLVTSFDPLIIYLYEEGIVRLATVKYDRHADNLWNPCMHLCNYSINKYHSDYIRSSDAQDEDVGHKWTLSALLRHLKLQSCDTRQLMLNIEDLIIKAVLACAQSIISACRMFVPNGNNCFELYGFDILIDNALKPWLLEINLSPSMGVDSPLDTKVKSCLMADLLTCVGIPAYSPEMKSHYDQKWSRFRSSSCQRIATFPSTSQKTKKSKKKGAAINLNLTGEEQRILRNARLQYSRRGGFVRIFPTDDSMQRYGNFLDSANGIPISTPNVQSQTFQTPIIQHNYNQMLHQNLYSKDGRQKQDDNNEADRIWQYERALETDSEIPFVKKPTVEKCEVEGRRLRKIMLKKISNGSELTPFQARQTFSMYLESVLRRLTEDPKDNHEKIILKFLNKFGGSVKPPVMFRNMQTIKVASKARSAMVAKLLGDFLENYKRDTEAYVDSFDHFGMIPSSAYNQFLMHAQESDLEAVLTLHTNVTGIMPFLYNRCGLSVPPTPPIPSGLHGFLRALPSMVSSTGINRELSKYDGYFKNFDKEKVFL
Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase) (P9WNS5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Interaction partners:
- Flavin-dependent thymidylate synthase
- Thymidylate synthase ThyA
- Putative lipoprotein LprE
- Nucleoside diphosphate kinase
- Thymidylate kinase
- dCTP deaminase, dUMP-forming
- Probable conserved alanine rich transmembrane protein
- Conserved alanine and glycine and valine rich protein
- Protein RecA
- Putative lipoprotein LppK
Sequence:
MSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGHGSSGGHASL
Protein: Ras-related protein RAB7 (EC 3.6.5.2) (C0H516)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Vacuolar protein sorting-associated protein 16, putative
- Vacuolar protein sorting-associated protein 18, putative
- Vacuolar protein sorting-associated protein 33, putative
- RING finger protein PFE0100w
- GDP dissociation inhibitor, putative
- Rab GDP dissociation inhibitor
- Vacuolar fusion protein MON1, putative
- Vacuolar protein sorting-associated protein 3, putative
- CCZ1/INTU/HSP4 first Longin domain-containing protein
- Tubulin alpha chain
Sequence:
MSNKKRTILKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKETIVDNEQITMQIWDTAGQERFQSLGVAFYRGADCCVLVFDLTNYKTYESLESWKDEFLIQASPKDPENFPFVIIGNKVDETNKRKVQSLKVLQWCKSNNNIPYFETSAKNAINVDQAFDEIARKAMKQEHQEEQIYLPETFALNNQSEQKMYKSRCC
Protein: Visual system homeobox 1 (Homeodomain protein RINX) (Retinal inner nuclear layer homeobox protein) (Transcription factor VSX1) (Q9NZR4)
Organism: Homo sapiens (Human)
Function: Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Dispensable in early retinal development (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q91V10}.
Interaction partners:
- Collagen alpha-2
- Nucleoredoxin-like protein 1
- Transcription factor ATOH7
- Collagen alpha-3
Sequence:
MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMIRKPGSEDKLAGLWGSDHFKEGSSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPGKVGAT
Protein: EG:52C10.2 protein (O96842)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSCTVSELPSGCRLRGMTASSQQSAANNSGNNGNGNGNGGGGGVVGGGGSLGGVSPTVGGSVGILGSTSNVLQESNATTLQRPQSQKPCCFCWCCCCSCSCLAIKNADENAPTKRDLVNAEFLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPR