wanglab/gogpt-training-data huggingface dataset:
Protein: X-ray repair cross complementing 3 (G3V3Q2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGATLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH
Protein: SEC24 homolog C, COPII coat complex component (A0A286YDN4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MNVNQSAPPVPPYGQNQPIYPGYHQSSYGGQPGPAAPATPYGAYNGPVPGYQQAPPQGSLVLSSLVLHWPLWSASQLCFSPMALPPQVHR
Protein: TBC1 domain family member 10B (Rab27A-GAP-beta) (Q4KMP7)
Organism: Homo sapiens (Human)
Function: Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, and RAB35. Does not act on RAB2A and RAB6A.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16923811}. Cell membrane {ECO:0000269|PubMed:19077034}. Note=Predominantly localizes near the plasma membrane (PubMed:16923811). In melanocytes, located at the periphery of cells (PubMed:16923811). {ECO:0000269|PubMed:16923811}.
Interaction partners:
- Ras-related protein Rab-35
- Ras-related protein Rab-27A
- Ras-related protein Rab-22A
- Cell division cycle protein 16 homolog
Sequence:
METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPSAEARQDAYF
Protein: Histidine ammonia-lyase (Histidase) (EC 4.3.1.3) (Q9HU85)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00229}.
Interaction partners:
- Urocanate hydratase
- Imidazolonepropionase
- Probable histidine/phenylalanine ammonia-lyase
- Probable transporter
- Probable amino acid permease
- Formimidoylglutamate deiminase
- Histidine utilization repressor
- N-formylglutamate deformylase
- Histidinol dehydrogenase
- Probable permease of ABC transporter
Sequence:
MSLHLKPGQLTLADLRQAYLAPVRLSLDPSADAPIAASVACVENIIAEGRTAYGINTGFGLLASTRISPADLEKLQRSIVLSHAAGVGEALDDAMVRLVMLLKVNSLARGFSGIRRKVIDALIALINAEVYPHIPLKGSVGASGDLAPLAHMSLVLIGESRARHRGEWLPAAEALAVAGLEPLTLAAKEGLALLNGTQVSTAYALRGLFEAEDLFAAATVCGGLSVEAMLGSRAPFDARIHAARGQRGQIDVAAAYRDLLTASSEVARSHEKCDKVQDPYSLRCQPQVMGACLTQMRQAAEVLEIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALALAEIGSLSERRISLMMDMHMSQLPPFLVANGGVNSGFMIAQVTAAALASDNKALAHPASVDSLPTSANQEDHVSMAPNAGKRLWAMAENVRGILAVEWLGACQGLDFREGLKSSPKLEQARRLLRDKVPYYQEDRFFAPDIEAASQLLASGCLNALLPARLLPSL
Protein: Pre-mRNA-splicing factor slu7 (Q9Y7Y2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Pre-mRNA-splicing factor 18
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-splicing factor brr2
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22
- Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16
- Pre-mRNA-splicing factor cwf14
- Pre-mRNA-splicing factor spp42
- Pre-mRNA-splicing factor cwf4
- Pre-mRNA-splicing factor cwf10
Sequence:
MSYMNNTFQSNYDYSKDKNFMSTDIGPSMREMKAQKRRSRPMDNPDADNPYIPKFISTAPWYAQDDDAVERLAHQRIGKKETPSGGRSSIEGSWYVRGKKLGPAATKYRKGACENCGAMSHKVKDCMERPRKRGARWTGEDIQADEVIQDINVSWDAKRDRWNGYDATDYKKVIERYEKLDELQNKGEENRDASENSAVKASRNSTVSGSEDSASITTPSLRMREDVVAYLRADNKNLQYEPKSRSMRDETGYHMVDDSSGGAGFVKASGGEKEDFEKLQMFAWEAERSGTRVHVVANPTAGELEFRKNKASRMTTQKHIDQSILDRYGDGTSKVKDKKAKNNEKEVPDLAILDKSEKSKGESNTDEESENLVIVEGDL
Protein: Carboxypeptidase A2 (EC 3.4.17.15) (P48052)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q9UI42}.
Interaction partners:
- Chymotrypsin-like elastase family member 3A
- Carboxypeptidase A1
- Mast cell carboxypeptidase A
- Chymotrypsin-like elastase family member 2A
- Chymotrypsin-C
- Chymotrypsin-like elastase family member 3B
- Latexin
Sequence:
MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY
Protein: Protein tiptop (Q9U3V5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Tiptop (tio) and teashirt (tsh) have, on the whole, common activities. Tio and tsh repress each other's expression and tsh has a crucial role for trunk patterning that is in part masked by ectopic expression of tiptop. Both genes share a common activity required for the activation of Ser and svb and the maintenance of en and wg.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- GH22493p
- Paired box protein Pax-6
Sequence:
MMLHEAVMLEIYRQALSASELTSPRCQSRDSNTSAGAGAGMADVRCPSNESHCSANDRLTPAATPTLTPTEATISPNSVGLPLTATLPPAAAVALLPPQSAAMAAYLAAAQQNHLLLTNPLAAAASLVQHATQQAVVEGEVESPALDFSRKRPKSHGDDDQEEDQEQDQEQEQEQEPDHDVQCDNGPLDLSVSTGKRQESVSPPARKIPRSISADYKSPLPPGSWMPPINPYLAAVAAKTGGLGYSKLAPSEASKALEKMTEMSRLETSPTAARSLGATSSVGAGVPAGASSNSGGRHSAWQSHWLNKGADTAKDVFKCVWCKQSFSTLANLTAHMKETQHCGVQIPSPLPTGGVGTPSAPPPTRLATSASNSACSSSSSSTSSSSNSSKSELNMLIKETMPLPRKLVRGQDVWLGKGAEQTRQILKCMWCGQSFRSLAEMTSHMQETQHYTNIISQEQIISWKSGDERERPTNTGVPSTSTAAPSSPSCTAPSVSAVLTCKVCDQAFGSLKELSTHMAQKSHYKESPAPSASPPAAGTGNPKRGRQNRNEKRKKSLPVRKLLELERSGSNSSLDSALKPLRDFAAATKITCEKCGSKIETALFVEHIRKCLGESIPIPPRRSNAGVDRLPSPSLGLGAEKPPSVLNALEQLIEKSFESRTSRTMTHGGYSEAGTPLGASILKRLGIEDSSDYTKPLMDAQAMHLLRSSFASRDRSASESSSASRVESSYTPDRQQATPHKSPDTPAPPPPPPPTIKAEPLEAEPLVGCDREGCSPRQQIQVKKEFSMEACRESPRSVSKSPAPQTERSPPDNGSLLALNSMFDQLSGVENSGNNNSGHCFNNNNSCSSVSAQKPKAHPLAALQKLCETTDPPSTGLRSASSAGSSTASATLPSANGNDLVAFSWACNEAVLSASNGGSAGDSSIIKCSYCDTPFASKGAYRHHLSKVHFVKDAGEDSPRLKSPAVQSPRSMPLASPRRSASRSPATGSQQPPPSPTISPYDESPQSKFLKYTELAKQLSSKNA
Protein: Serine/threonine protein kinase, FIKK family (EC 2.7.11.1) (Q8IFL9)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Small ribosomal subunit protein eS30
Sequence:
MNYFSKYKVIESNRLLYTSNVKYDNYFININKKNQVKNKNESYSFIKLLFRKCIIFFIIYFLFIIPLNEVIYNKYDYSSKSIQHYCIRNLSECFRGKSALNDDSESCRCSNLLKEKKKTEENSEEIRKYLSDKTKKRNSLYKYKLKGSKGKSVKNIVGNKEGSIHENTDLYSDSDVEYDYGNLFYDCYYTEGLIDQGEENEEEKFYEAREDFEGEEKNKCKIKESEKSFKKENDCKVENVENINYERVYSWELGKEALTKLLGCSNKLSVNNVKYSDWKFKSIPTVGFSKDGDRLQEMYKASVCSYTEECQGEVYLFVKKIPIEVWIRQYNLMNDNDGEYLLDGENFIMEAVACAYLSEHYPGLTPKLYKVLYEPECANCNEEDKNMSENNHKKDSKHKGDSNHKSDSNHKSDSNHKSDSNHKSGSNHKSDCNHKSGSNHKSDSNHQSDCNHMSDHNHKSDNNHKSDSSHKSDSSHKSDSSHKSGSNHKSDNNHKSDSSHKSGSNHKSDHNHKSDSNHKSDSNHKNESNHKNESNHKNESNHKNESNHKNESNHKNDSNHKSDSNHMSDHNHKSDNNHKSDHNHMSDHNHKSDNNHKSDNNHMSDHNHKSDNNHKSDNNHKSDNNHKSDHNHMSDHNHKSDNNHKSDHNHKSDSNHMSDHNHMSDHNHKSDHNHKSDHNHKSDNNHKSDSNHKSDSNHKSDHNHKSDSNHMSDHNHMSDHNHKSDHNHKSDNNHKSDSNHKSDSNHKSDHNHKSDSNHMSDHNHMSDHNHMSDHNHKSDHNHKSDNNHKSDSNHKSDSNHKSDSNHKSDHNHKSDHKHMSDNNHKSDNNHKSDHNHKSDNNHKSDHNHKSDSNHKSDSNHKSDSNHKSDSNHKSDNNHKSDHNHNSDSNHMSDHNHKSDHNHKSDHNHKSDNNHKSDNNHKSDHNHKSDHKKNNNNNKDNKNDDNDDSDASDAVHEDIELLESYSDLNKFNEMLTEQLNKNKDGYVVLVTELFGEDLFQYINKRNENEDTRVRDEDKKIIMFEFLKLLIKLHNAGLVHLDISPENILIENNGELRLCDLAKCAPMYTHNLRHIKGNGNDLYSFQSCQPCVGKIPCIPKECWDIIREHIKLKIDNPFEHLSTITDQEERKKYYFDVHCVDKYMLGIFYIWIWNLNYIWKRADPPNDRTFNNFLKYNLNINVFQLAKQWPKGLKDIINKLLSLESRMKTDLNELTEHPWWINED
Protein: Alveolar macrophage chemotactic factor (Neutrophil chemotactic protein) (NPC) (P82535)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Has chemotactic activity for neutrophils.
Subcellular location: Secreted.
Interaction partners:
- C-X-C chemokine receptor type 2
- C-X-C chemokine receptor type 1
- Chemokine
- C-C motif chemokine
- C-C motif chemokine 2
- C-X-C chemokine receptor type 4
- C-X-C motif chemokine ligand 11
- C-C motif chemokine
- Lymphotactin
- C-C motif chemokine
Sequence:
GPVAAVVRELRCVCLSTTAIHPKMIARLQVIAAGPQCSKVEVVASLKNGKEICLDPEAPLIKKAIQKILESGNKEN
Protein: Transcription factor SOX-21 (SOX-A) (Q9Y651)
Organism: Homo sapiens (Human)
Function: May play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can up-regulate the OPRM1 distal promoter activity in mor-expressing neuronal cells. May play a role in ameloblast differentiation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
- Transcription factor SOX-2
Sequence:
MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL
Protein: Kdo(2)-lipid A phosphoethanolamine 7''-transferase (EC 2.7.8.42) (Phosphoethanolamine transferase EptB) (P37661)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the addition of a phosphoethanolamine (pEtN) moiety to the outer 3-deoxy-D-manno-octulosonic acid (Kdo) residue of a Kdo(2)-lipid A. Phosphatidylethanolamines with one unsaturated acyl group functions as pEtN donors and the reaction releases diacylglycerol.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15795227}; Multi-pass membrane protein {ECO:0000269|PubMed:15795227}.
Interaction partners:
- Lipid A 1-diphosphate synthase
- Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
- Lipid A palmitoyltransferase PagP
- Phosphoethanolamine transferase EptA
- Lipid A biosynthesis myristoyltransferase
- Sensor protein PhoQ
- Transcriptional regulatory protein PhoP
- Sensor protein BasS
- Protein YhjJ
- Transcriptional regulatory protein BasR
Sequence:
MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWKGISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRSLAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAWARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDLYAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLIILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVIDQVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQAFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAKEAAAN
Protein: CAG pathogenicity island protein 12 (P97245)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Cag pathogenicity island protein
- Cag pathogenicity island protein
- Cag pathogenicity island protein
- Cag pathogenicity island protein
- Type IV secretion system protein CagE
- Cag pathogenicity island protein
- Cag pathogenicity island protein
Sequence:
MKLRASVLIGATILCLILSACSNYAKKVVKQKNHVYTPVYNELIEKYSEIPLNDKLKDTPFMVQVKLPNYKDYLLDNKQVVLTFKLVHHSKKITLIGDANKILQYKNYFQANGARSDIDFYLQPTLNQKGVVMIASNYNDNPNSKEKPQTFDVLQGSQPMLGANTKNLHGYDVSGANNKQVINEVAREKAQLEKINQYYKTLLQDKEQEYTTRKNNQREILETLSNRAGYQMRQNVISSEIFKNGNLNMQAKEEEVREKLQEERENEYLRNQIRSLLSGK
Protein: EMG1/NEP1 methyltransferase (Q586T6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nop14-like protein
- KRR1 small subunit processome component
- CCAAT-binding factor domain-containing protein
- PIN domain-containing protein
- HEAT repeat-containing protein 1
- Nrap protein domain-containing protein
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- U3 small nucleolar RNA-associated protein 14
- U3 small nucleolar RNA-associated protein 18
- U3 snoRNA-associated protein UTP11, putative
Sequence:
MPPSHTLLNRRGQQFSSRMHVGAKRKRVEDNASPVSSLYRPLCRGLSTRGSGASAVSCPSVVVILEKAGLLLGREGVVDAYDRAGSTTIANASLRDVRPDIVHQCLLALFDSGLAQEQRQLRVFINLFSRGGRTVEVSPSLRPPRTLRRFKGLVAALLRDGVVRSQDGEVLLQVLPGSLAPVLPYGAEVIGLTNAHSAPVRTPTQLARAALENPVDDKLQGGLKGVAGFFCICCSEDGSLDGVDYVTQQVCLSAYPMTAHVMCSRLCEGFSRAAATGNR
Protein: Zinc finger protein CONSTANS-LIKE 3 (Q9SK53)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
Interaction partners:
- B-box zinc finger protein 32
- E3 ubiquitin-protein ligase COP1
- B-box zinc finger family protein
- B-box domain protein 30
- AT5g19430/F7K24_180
- B-box domain protein 31
- Putative F-box protein At1g32420
- Putative F-box/kelch-repeat protein At1g32430
- Kanadaptin-like protein
Sequence:
MASSSRLCDSCKSTAATLFCRADAAFLCGDCDGKIHTANKLASRHERVWLCEVCEQAPAHVTCKADAAALCVTCDRDIHSANPLSRRHERVPITPFYDAVGPAKSASSSVNFVDEDGGDVTASWLLAKEGIEITNLFSDLDYPKIEVTSEENSSGNDGVVPVQNKLFLNEDYFNFDLSASKISQQGFNFINQTVSTRTIDVPLVPESGGVTAEMTNTETPAVQLSPAEREARVLRYREKRKNRKFEKTIRYASRKAYAEMRPRIKGRFAKRTDSRENDGGDVGVYGGFGVVPSF
Protein: receptor protein serine/threonine kinase (EC 2.7.11.30) (Q8IPK9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAAAALSGMEMGSGPGSEGYEDADNEKSKTVENARSLTCYCDGSCPDNVSNGTCETRPGGSCFSAVQQLYDETTGMYEEERTYGCMPPEDNGGFLMCKVAAVPHLHGKNIVCCDKEDFCNRDLYPTYTPKLTTPAPDLPVSSESLHTLAVFGSIIISLSVFMLIVASLCFTYKRREKLRKQPRLINSMCNSQLSPLSQLVEQSSGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRDERVAVKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGNGSWTQMLLITDYHEMGSLHDYLSMSVINPQKLQLLAFSLASGLAHLHDEIFGTPGKPAIAHRDIKSKNILVKRNGQCAIADFGLAVKYNSELDVIHIAQNPRVGTRRYMAPEVLSQQLDPKQFEEFKRADMYSVGLVLWEMTRRCYTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDVLATVSKIMQECWHPNPTVRLTALRVKKTLGRLETDCLIDVPIKIV
Protein: DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Q8K382)
Organism: Mus musculus (Mouse)
Function: Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes. Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P.
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000269|PubMed:17182770, ECO:0000269|PubMed:20159556}; Peripheral membrane protein {ECO:0000269|PubMed:17182770, ECO:0000269|PubMed:20159556}. Presynaptic cell membrane {ECO:0000269|PubMed:17182770}. Note=Associates to membranes via lipid-binding activity. {ECO:0000269|PubMed:20159556}.
Interaction partners:
- Ras-related protein Rab-35
- DENN domain-containing protein 1B
- 14-3-3 protein epsilon
- TOX high mobility group box family member 3
Sequence:
MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQESQWNELLETLHRLPIPDPGVSVHLSVHSYFTVPDSRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFSEEAFVSHYRSGAMKQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDITENGCVSSAEDPLPKTMPSPQAETQDPRLREDRRPITVHFGQVRPPRPHVVRRPKSNITVEGRRTSVSSPEQPQPYRTLKESDSAEGDETESPEQLVREPWGPTPAPPDRAASIDLLEDVFSSLDVEAPLQPLGQAKSLEDLRAPKDLREQPGSFDYQRLDLCRSERGLSMAAALKLAHPYTKLWSLGQDDMAIPSKPSITSPEKPSALLGTSPALPLRPQNQEGILSPSIKEETPIPTPGSITIPRPQGRKTPELGIVPPPPTARPAKLQAAGGPLGDFSSEPLQMDRERQAALSPALLSGLLPRAVPQGPTELLQPPSPAPGAAGTGSDALLALLDPLNTAWSGSTIPSHPATPSAATPFIPQLSFPPTVTPTPFVQTPLNPFVPSVPVVPPSMPLSSTPARPFGTPPASLGPAYAPSILLSSSGFYAPHRSQPNLSALSMPNLFGQIPMGAHTSPLQPLGPPAVAPSRIRTLPLARSSARAAEAKQGLALRPGESPLLPPRPPQSLQPTPQPSVPTQARDPFEDLLRKTKQDVSPSPAPALAPASTSVEQLRRQWETFE
Protein: Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) (P23492)
Organism: Mus musculus (Mouse)
Function: Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (Probable). Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (Probable).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P00491}.
Interaction partners:
- Adenosine deaminase
- Guanine deaminase
- Adenine phosphoribosyltransferase
- Hypoxanthine-guanine phosphoribosyltransferase
- Adenosine kinase
- Xanthine dehydrogenase/oxidase
- Nicotinamide riboside kinase 1
- Uracil phosphoribosyltransferase homolog
- Thymidine phosphorylase
- Nicotinamide riboside kinase 2
Sequence:
MENEFTYEDYETTAKWLLQHTEYRPQVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQSTVQGHAGRLVFGLLNGRCCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFTAWKQMGEQRKLQEGTYVMLAGPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYENLEKANHMEVLDAGKAAAQTLERFVSILMESIPLPDRGS
Protein: Uncharacterized protein (Q57YI4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Elongation factor Ts, mitochondrial
- phenylalanine--tRNA ligase
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- Small ribosomal subunit protein uS4
- Centromere/microtubule binding protein cbf5, putative
- CTP synthase
- Tetratricopeptide repeat domain 5
- Ribosomal protein
- rRNA biogenesis protein, putative
- Plastid-encoded RNA polymerase subunit alpha
Sequence:
MEFVAEAHGYLITGLALDSQGDLFAICSCSGELLRLNKEENTLVSIMATEASPYNIAIEPNSGSVFITDRSENAILKLEDAATVRAEQELREGKDQESQAAYTTVQYLNAFEGRSFLGPTAIAFSPSGELFFTDAGAEGDSSFSDPVGAVYRTTMNHEHLVPICTRGLIRPSAIAVAPDNSVYVCEQGTNRVLRFVQRSTFYVGNVFAQLQGGMGPRAIAVSPRDGSVFVAQYDISAVEAPTEEGESEKGNEDAGEGEGGDDGKVQNQSALESAGEGGIITVLGRDGDVRGIVRTMRPCITAIALDASGETLYVMEGDEANGSSKLYKLQVLPLDDQQCGGQAE
Protein: Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A) (Q3UPL0)
Organism: Mus musculus (Mouse)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:O94979}; Peripheral membrane protein {ECO:0000250|UniProtKB:O94979}; Cytoplasmic side {ECO:0000250|UniProtKB:O94979}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associates with membranes in a GTP-dependent manner (By similarity). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:25201882). {ECO:0000250|UniProtKB:Q9Z2Q1, ECO:0000269|PubMed:25201882}.
Interaction partners:
- Protein SEC13 homolog
- Protein transport protein Sec23A
- SEC24 homolog B, COPII coat complex component)
- Protein transport protein Sec23B
- Protein transport protein Sec24A
- Small COPII coat GTPase SAR1B
- SEC24 homolog D, COPII coat complex component)
- Small COPII coat GTPase SAR1A
- SEC24 homolog C, COPII coat complex component
- Peflin
Sequence:
MKLKEIDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAVAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSIDGLRQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQSAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFESVAVPLQQGAEQQRRQPVFISQVVTEKDFLNRSAQLQHAVQSQGFIGYCQKKIEASQTEFEKNVWSFLKVNFEEDSRGKYLELLGYRKEDLGQKIALALNKVDGPDVALKDSDQVAQSDGEESPAAEEQLLGERIKEEKQECDFLPSAGGTFNISVSGDIDGLITRALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLAQTQKKYFAKSQSKITRLITAVVMKNWREIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLEREGDSLLRTQACLCYICAGNVERLVACWTKAQDGSSPLSLQDLIEKVVILRKAVQLTQALDTNTVGALLAEKMSQYASLLAAQGSIAAALAFLPDNTNQPNIVQLRDRLCKAQGKPVSGQESSQSPYERQPLSKGRPGPVAGHSQMPRVQTQQYYPHGENPPPPGFIMQGNVIPNPAAPLPTAPGHMPSQLPPYPQPQPYQPAQQYSFGTGGAAAYRPQQPVAPPASNAYPNTPYISPVASYSGQPQMYTAQQASSPTSSSAASFPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTPPAASELPASQRTENQSFQDQASILEGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPSGDPQSQGLQQQPSTPGPLSSHASFPQQHLAGGQPFHGVQQPLAQTGMPPSFSKPNTEGAPGAPIGNTIQHVQALPTEKITKKPIPEEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLSPTIINGLHSIARSIETRNYSEGLSVHTHIVSTSNFSETSAFMPVLKVVLSQASKLGV
Protein: Myosin binding subunit, isoform Q (M9PCQ3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKKPTVTIATSTAATAINSPSTTVQTPPIRRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGNETSSASSTSAPTPSILGSNEQQDELQPPPPPTTPPPAVIPTTTTATDETEIEEVVSSPPAGQSQNDTTASFTLSAPVRRSLSTEGEADANSDPEGDQDQTVVSASYTIMPRRERLPESSENVESIRSPQKTEPVAKSSSEDKSEEPPHARPTDLPLIPAPAAPSTEAIKSSSAATTPAALESPVRLRDKRGLSGSQESETKSDTASPVSSHPDFNARDSLLSLYARRTTDSSAGGGGVGGGAGVGAGGASGAATSSSTSAAERRPSWRLKFDAGSKFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSNDKTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFANATTKNSLSELEKRERRAMERKLSELEEELKLLQKLKTENDRLRAENRALTRVVSKLTTSAQSQLAKSK
Protein: SPRY domain-containing protein C285.10c (O74497)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- GID complex subunit 7
- Inactive zinc metalloprotease C354.09c
- GID complex subunit 8
- Putative E3 ubiquitin-protein ligase C36B7.05c
- E3 ubiquitin-protein ligase gid2
- Myo-inositol transporter 1
- GID complex subunit 9
- Probable metal homeostasis protein bsd1
- Uracil permease
- GID complex substrate-recognition subunit 4
Sequence:
MHPDQIRQLRLQESSNTHPNLAILFIFIALAAVIVLLICLLSVILLLRYTRHGRILLKNTNPGELDDEALENEHIDEEGFSLLDDMGKERYLQAREFELNSMKSNVNTDAKLLDFLQVQEKGVLAWHFIPNQEYNCYVKNKTELSFLGNEECCMQTNLPLQRINEVYYFEVKLLDVPIDTLVSIGLATKPYPPFRLPGWNFWSTAYVSDGTRRSNSPFTGKPYSSFYQQGDVIGVGYKPKCNRIFFTRNGRRCAELPCTYRNLYPTVGAIGPCTLHVNLGQAGYVFIEANIKKWRLAPAVGSLAPPPSYSTSQPTISWDAASESSAGTTTQGDTNRPDKSKNRSPPINFDGTSYDAAGNVFSPSSSNNQAYQMHSMPATDEV
Protein: Cysteine desulfuration protein SufE (PfSufE) (O96155)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Plastid, apicoplast {ECO:0000269|PubMed:24086138, ECO:0000269|PubMed:24709262}.
Interaction partners:
- BolA-like protein, putative
- Anamorsin homolog
- Glutaredoxin-like protein
- 1-cys-glutaredoxin-like protein-1
- Glutaredoxin-like protein
Sequence:
MNKKKLKAHFFVLYIICSCFILILSIKHDKYNNESKKKKKFFKIRTKIIFYKLKKVNQIKNAPQLYIQFYKPKCHKTTQSLKDIFNELSGNKNPENPKNIDEYNLTPKLKKTVELFQSMPNSPYYKSQQVILMGKKISSMPDKHKIRQNQVLGCQSVVYIYPKVEENEDKKKVIVWLGHSDGLLTKGIVYILTDGLSGYMPEDILKVNPNFITLTGISEFLTMSRINGYLNIMNKIKIFCTNILKNMDN