wanglab/gogpt-training-data huggingface dataset:
Protein: SPRY domain-containing protein (Q38AN1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDSINSVTFEWVRAGPAYTLDGPHVYHSGCLGSYQPAIGGLEMPAGHGKYFYEIQTSDTRCKVGVCTEDAFLSNVNLGDVELHAAQPSSSLNSRLSEANCCLFNCLTCAVEVNGVEVRSLWRLLVPSAGARFGFLVNTDEGAVQLYVNGEYQGLIADTATGFKGKKLRPCIALDAPPTCGAGAEANKSSASVVPPRKIIASTA
Protein: Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2) (TNF alpha-induced protein 8-like protein 2) (TNFAIP8-like protein 2) (Inflammation factor protein 20) (Q6P589)
Organism: Homo sapiens (Human)
Function: Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21459448, ECO:0000269|PubMed:27043859, ECO:0000269|PubMed:32460619}. Nucleus {ECO:0000269|PubMed:21459448, ECO:0000269|PubMed:27043859}. Lysosome {ECO:0000269|PubMed:32460619}.
Interaction partners:
- Caspase-8
Sequence:
MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLDEGKL
Protein: VSG-like protein (Q26807)
Organism: Trypanosoma brucei
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MPRNSGRTTSTLALAVALKLLAVPVSPSGTAFDEEPVKKVCKVEKNLADVAGIALAKINNLIKQVSAATEAEARMTLAAASTDHSNISALYAAASNIVTRCVLNAVHALTSLAPIALTAATNGAKTSGHISEVIDILQQASQGKTEGKCIVKSGGGTTTVAIRQLYNKIGDLEKQTTNNCGTSVTEVLEHILKQEALKEAVLSIVKKPKGAPDKTAADELVTALINGVVPNSTAQTQKLKEKILNTLVPKLVEGSKSQVKLRILKYPGKIQKSKLVSIQELKTRVEPESSTESCKQQVATNQAQEAFCNAIGDDKDKCNNETRCSYDDSKGSDKKCTYNAEKAEANGAPATQPQGGVNEATTGNCKGKLEPGCTKAQEYEWEGKESKDSSFLVDMKLALNMVAAFVAFLF
Protein: Synchronized import protein 1 (Symportin 1) (Q07395)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Nuclear import adapter that specifically recruits the two functionally and topologically linked ribosomal proteins RPL5 and RPL11 (encoded by RPL11A and RPL11B). Guarantees that this cargo pair remains bound together from the time of synthesis in the cytoplasm until delivery to the nascent 5S rRNA in the nucleus.
Subcellular location: Cytoplasm. Nucleus. Note=The SYO1/RPL11/RPL5 complex is transported into the nucleus by KAP104.
Interaction partners:
- Large ribosomal subunit protein uL18
- Ribosome assembly protein RRB1
- Ribosome biogenesis protein RPF2
- Assembly chaperone of RPL4
- Ribosome assembly protein 4
- Protein BCP1
- Large ribosomal subunit protein uL5A
- Probable metalloprotease ARX1
- Pre-rRNA-processing protein TSR2
- Ribosome assembly protein SQT1
Sequence:
MGRSKKRSRASSSRLNPLRKAGSNDNNKDTNVVNKKLQPLLQNLSSVVPNDRSIALSSISVLCEDAHMRQLLLKEKLVPIILNKLLNDSNSDIVVESFGLLRNLSLEEGYDVSIYLWRSDIWTSITSNFGRIVESLSALQAAEQQPQLKPAGKSKIESKRLLFDFADNLLSLVVALSNGSDDILNEILTESKINEIFQVISQLLKYGVEKLPINLFNTTLDLIYDLSSESFEFIDHVSNNELLSQFLNGLSPALHPQANELTKVLIEGIHCQFLDMKITYDQCNKMIHSVCHSINNIDPVQLVNDINNPVEIGPATSKDESSKVITKIKDYNAKRNESMIKLQSIEIAIDLITAIIEIVASKYESPESQEVAIPEELINTLTNFLPHVFMILKDTFTSRILIGWNNLIWLFVSLSLTELSGELLTTLWSYVTQLDSQDDLSIKIGRMGCIWALLKLIFPDGAFESENRALINVQMLNNSGFARGIIEEFQNNNDLELQQKCINVLSTYAMIQGQIDANKEIGQFFIQTLTQLNVRPEILIEMTNSLFQIYGDASYDYNEPIFVRGGFLSILKDQVVPNLRQQFKMVDKNKNPELKERCHDCFTTLDSFIHYKMNENSTNQ
Protein: oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) (Q9FLH2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1, mitochondrial
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2, mitochondrial
- Dihydrolipoyl dehydrogenase 2, mitochondrial
- Dihydrolipoyl dehydrogenase 1, chloroplastic
- Dihydrolipoyl dehydrogenase 2, chloroplastic
- Dihydrolipoyl dehydrogenase 1, mitochondrial
- Peroxisomal isocitrate dehydrogenase
- Isocitrate dehydrogenase, chloroplastic/mitochondrial
- Succinate--CoA ligase subunit alpha-1, mitochondrial
- Cytosolic isocitrate dehydrogenase
Sequence:
MVWFRIGSSVAKLAIRRTLSQSRCGSYATRTRVLPCQTRCFHSTILKSKAESAAPVPRPVPLSKLTDSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRNFVGQASTSPGISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLEKREIPEDLTPGLYGFTEADLDREFFLGVWRMSGFLSENRPVQTLRSILSRLEQAYCGTIGYEYMHIADRDKCNWLRDKIETPTPRQYNSERRMVIYDRLTWSTQFENFLATKWTTAKRFGLEGAESLIPGMKEMFDRSADLGVENIVIGMPHRGRLNVLGNVVRKPLRQIFSEFSGGTRPVDEVGLYTGTGDVKYHLGTSYDRPTRGGKHLHLSLVANPSHLEAVDPVVIGKTRAKQYYTKDENRTKNMGILIHGDGSFAGQGVVYETLHLSALPNYCTGGTVHIVVNNQVAFTTDPREGRSSQYCTDVAKALSAPIFHVNADDIEAVVHACELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRSHPSSLQIYQEKLLQSGQVTQEDIDKIQKKVSSILNEEYEASKDYIPQKRDWLASHWTGFKSPEQISRIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWGLGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLIKNQDPEMFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPYVIPEMDPTLRKQIQECNWQVVNVTTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKQCVSNLSEFDDVKGHPGFDKQGTRFKRLIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERKKSETKDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEPMNMGGYQYIALRLCTAMKALQRGNFNDIKYVGRLPSAATATGFYQLHVKEQTDLVKKALQPDPITPVIP
Protein: mRNA cleavage and polyadenylation factor CLP1 (Q08685)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the cleavage factor IA (CF IA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation. Associates with HRB1/CF IB to form the cleavage factor I (CF I) complex. CF I is required for correct positioning of a larger protein complex, the cleavage and polyadenylation factor (CPF) complex, which contains the catalytic subunits executing mRNA cleavage and polyadenylation. CLP1 mediates interactions between CF IA and CPF factors. CLP1 is also involved in maintaining the CF IA interaction with the C-terminal domain of RNA Pol II largest subunit via PCF11, which links pre-mRNA 3'-end processing to transcription termination.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03035}.
Interaction partners:
- Protein PCF11
- mRNA 3'-end-processing protein RNA15
- mRNA 3'-end-processing protein RNA14
- Transcription factor tau 131 kDa subunit
- mRNA 3'-end-processing protein YTH1
- Pre-mRNA polyadenylation factor FIP1
- Endoribonuclease YSH1
- Cleavage factor two protein 2
- Nuclear polyadenylated RNA-binding protein 4
- Protein CFT1
Sequence:
MASLPGIDEHTTSEELITGDNEWHKLVIPKGSDWQIDLKAEGKLIVKVNSGIVEIFGTELAVDDEYTFQNWKFPIYAVEETELLWKCPDLTTNTITVKPNHTMKYIYNLHFMLEKIRMSNFEGPRVVIVGGSQTGKTSLSRTLCSYALKFNAYQPLYINLDPQQPIFTVPGCISATPISDILDAQLPTWGQSLTSGATLLHNKQPMVKNFGLERINENKDLYLECISQLGQVVGQRLHLDPQVRRSGCIVDTPSISQLDENLAELHHIIEKLNVNIMLVLCSETDPLWEKVKKTFGPELGNNNIFFIPKLDGVSAVDDVYKRSLQRTSIREYFYGSLDTALSPYAIGVDYEDLTIWKPSNVFDNEVGRVELFPVTITPSNLQHAIIAITFAERRADQATVIKSPILGFALITEVNEKRRKLRVLLPVPGRLPSKAMILTSYRYLE
Protein: Sorting nexin-12 (Q9UMY4)
Organism: Homo sapiens (Human)
Function: May be involved in several stages of intracellular trafficking.
Subcellular location: Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Sorting nexin-3
- Vacuolar protein sorting-associated protein 35
- Sorting nexin-6
- Sorting nexin-5
- Vacuolar protein sorting-associated protein 26A
- Vacuolar protein sorting-associated protein 26B
- Sorting nexin-1
- Vacuolar protein sorting-associated protein 29
- Sorting nexin-2
- Sorting nexin-27
Sequence:
MSDTAVADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVRQ
Protein: Metallopeptidase AprA (EC 3.4.24.-) (Heat-resistant peptidase) (A0A0C5CJR8)
Organism: Pseudomonas marginalis (Pseudomonas panacis)
Function: Peptidase able to cleave azocasein and the milk substrates beta-casein and Na-caseinate. Can withstand UHT processing of milk, and is able to spoil UHT milk over the storage period.
Subcellular location: Secreted {ECO:0000269|Ref.1}.
Interaction partners:
Sequence:
MSKAKDKAIVSAAQASTAYSQIDSFSHLYDRGGNLTINGKPSYTVDQAATQLLRDGAAYRDFDGNGKIDLTYTFLTSASSSTMNKHGISGFSQFNAQQKAQAALAMQSWSDVANVTFTEKASGGDGHMTFGNYSSGQDGAAAFAYLPGTGAGYDGTSWYLTNNSYTPNKTPDLNNYGRQTLTHEIGHTLGLAHPGDYNAGEGAPTYNDATYGQDTRGYSLMSYWSESNTNQNFSKGGVEAYASGPLIDDIAAIQKLYGANYNTRAGDTTYGFNSNTGRDFLSATSNADKLVFSVWDGGGNDTLDFSGFTQNQKINLNEASFSDVGGLVGNVSIAKGVTIENAFGGAGNDLIIGNNAANVIKGGAGNDLIYGAGGADQLWGGAGNDTFVFGASSDSKPGAADKIFDFTSGSDKIDLSGITKGAGLTFVNAFTGHAGDAVLTYAAGTNLGTLAVDFSGHGVADFLVTTVGQAAVSDIVA
Protein: Beta-1,4-galactosyltransferase 1 (EC 2.4.1.38) (UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1) (Q567N4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSESVGFFTKACVVLVLLCGLHLIVALIFYLSESPLAKFRNYRHISFISDMVNSQTHGELGQADNETLDVAVYKRIYNNETVIIGDVEKPAEVLESCPETSPLLVGQLRVEFSTPVDFNLVRQGNKHLTMGGRYTPTKCVALQKVAMITPYRNREEHLKYWLYYLHPILKRQLLDYGIYIIEQDGENTPNKTLKSLTICILGLSLRISVTLMVE
Protein: Glutaredoxin-C1 (AtGrxC1) (Q8L8T2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Monothiol glutaredoxin-S14, chloroplastic
- Bifunctional monothiol glutaredoxin-S16, chloroplastic
- Monothiol glutaredoxin-S15, mitochondrial
- Protein BOLA2
- Thioredoxin H1
- Monothiol glutaredoxin-S13
Sequence:
MGSMFSGNRMSKEEMEVVVNKAKEIVSAYPVVVFSKTYCGYCQRVKQLLTQLGATFKVLELDEMSDGGEIQSALSEWTGQTTVPNVFIKGNHIGGCDRVMETNKQGKLVPLLTEAGAIADNSSQL
Protein: Phosphodiesterase (EC 3.1.4.-) (A0A8I5Y792)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MGSTDTDIEELENATYKYLIGEQTEKMWQRLKGILRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIFVERMYRKNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAVHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILVNLSKDDWRKRKEGPRIDRAKTMSLILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLIEEASKPESSNYGASSSSTMIGFHVADALRRSNTKGCMSDGTYAPDYSLSAVDLKSFKNNLVDIIQQNKERWKELAAQGELDLHKNSEDLEEKHADTHP
Protein: Protection of telomeres protein 1 (E7F0D5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome, telomere {ECO:0000256|ARBA:ARBA00004574}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- ACD shelterin complex subunit and telomerase recruitment factor.
- TERF1
- Telomerase reverse transcriptase
- Telomeric repeat-binding factor
- WRN RecQ-like helicase.
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- Eukaryotic translation initiation factor 2 subunit 3
- CST complex subunit CTC1
- Telomeric repeat-binding factor 2-interacting protein 1
Sequence:
MPVEKVNNSSDLDTKVPSCLQLTSIGQLTLTSDPSHRCVKARVLRKGPVISCAQRDGLEMLRAEIREEDPLQSTTEHTSINVIFFDTLAKDFSQSVKQGDIVLLANFTISKSPTFLRDKLHPCQLEMDNKDACVYVCPSAIPGPSSSEAKYVYVPLNKLKSKTLVNVYGVVTFFKQPFPSKGSDYCTTLKITDQSDVKVICTIFCKKLEDHPLIFRVGDIIRLHRFKAEAFRDSITLINTFGWSTVTFNGIIDSPIVPRTSSKSFFYGEADKRRVQELRQWAANQSLCSDLNTSLSSVQPHMYFDFTCQLLAKAVMHSGCILLKVWDGTRCQLPLLQVAVPPDELEGECTLAKDKMNLTANVLVYDNHLEVARDLKPGAFLRFYNLRALLQKVPGQLPDQPEHLGFHLHGGTVYGRGLRSLPAETPDLLSLKSVLEKHVDLDEHEEVNDGTLLEIWYTPPESIVLPNDENPGAEENAGPAYTVQTCEHNTQRITLAQVKRSTPPLSCHVRARVKKYLPQQLYQCLKLFCSKCKTMKDVPDDSAVANIFLESARDNQPCDEQWAATSSANSREPGRTISMHVSKDMVGKSSHMQLIFIEGMTLDEISVLSRDHKNLVPVRSENSKMTRMDLTAPFLFSGKKRYYGCKQCSRNTFENPVFTGVETWDEQAVAAVLGVQMMQYRFLIQFELDDVTDTIEALLWEDAERFFHISAVDASGCQDLQDRIQTIMDTIQPPESSLEERPWMDFCLSVYTVKDNDRNKVCYQITNTEIVKQ
Protein: SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1) (A6NKF1)
Organism: Homo sapiens (Human)
Function: Involved in centrosome duplication and mitotic progression.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Localizes on centrosomes in interphase cells and at spindles in mitosis. {ECO:0000250}.
Interaction partners:
- Transcription and mRNA export factor ENY2
- PCI domain-containing protein 2
Sequence:
MAGRRAQTGSAPPRPAAPHPRPASRAFPQHCRPRDAERPPSPRSPLMPGCELPVGTCPDMCPAAERAQREREHRLHRLEVVPGCRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPSVLLATVRYLAGEVAESADIARAEVASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLLTVVARLGPDAARGPADPVLLQAQVQEGFGSLRRCYARGAGPHPRQPAFQGLFLLYNLGSVEALHEVLQLPAALRACPPLRKALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGHARREALARFARAFSTPKGQTLPLGFMVNLLALDGLREARDLCQAHGLPLDGEERVVFLRGRYVEEGLPPASTCKVLVESKLRGRTLEEVVMAEEEDEGTDRPGSPA
Protein: Serine carboxypeptidase 24 (EC 3.4.16.6) (Bri1 suppressor 1) (Carboxypeptidase D) (Serine carboxypeptidase II) [Cleaved into: Serine carboxypeptidase 24 chain A (Serine carboxypeptidase II chain A); Serine carboxypeptidase 24 chain B (Serine carboxypeptidase II chain B)] (Q9M099)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Active serine carboxypeptidase with broad substrate preference, including basic and hydrophilic groups. Processes a protein involved in an early event in the brassinosteroid signaling pathway.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:16123046}.
Interaction partners:
- Serine/threonine-protein kinase BSK1
- Serine/threonine-protein phosphatase BSU1
- Protein BRASSINOSTEROID INSENSITIVE 1
- Protein BRASSINAZOLE-RESISTANT 2
- Shaggy-related protein kinase eta
- Protein BRASSINAZOLE-RESISTANT 1
- BRI1 kinase inhibitor 1
- BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1
- Serine/threonine-protein phosphatase BSL1
- Transcription factor PRE3
Sequence:
MARTHFIFLLLVALLSTTFPSSSSSREQEKDRIKALPGQPKVAFSQYSGYVNVNQSHGRALFYWLTESSSPSPHTKPLLLWLNGGPGCSSIAYGASEEIGPFRINKTGSNLYLNKFAWNKDANLLFLESPAGVGYSYTNTSSDLKDSGDERTAQDNLIFLIKWLSRFPQYKYRDFYIAGESYAGHYVPQLAKKINDYNKAFSKPIINLKGFLVGNAVTDNQYDSIGTVTYWWTHAIISDKSYKSILKYCNFTVERVSDDCDNAVNYAMNHEFGDIDQYSIYTPTCVAAQQKKNTTGFFVRMKNTLLRRRLVSGYDPCTESYAEKYFNRPDVQRAMHANVTGIRYKWTACSDVLIKTWKDSDKTMLPIYKELAASGLRIWIFSGDTDSVVPVTATRFSLSHLNLPVKTRWYPWYTDNQVGGWTEVYKGLTFATVRGAGHEVPLFEPKRALILFRSFLAGKELPRSY
Protein: Iron(III) enterobactin esterase (EC 3.1.1.108) (Enterochelin esterase) (Ferric enterobactin esterase) (O51900)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Function: Catalyzes the hydrolysis of ferric enterobactin (Fe-Ent). Is responsible for the release of iron from ferric enterobactin.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P13039}.
Interaction partners:
- isochorismatase
- Chrysobactin synthetase cbsF
- Ferric chrysobactin binding proteinpermease periplasmic component
- 2,3-dihydroxybenzoate-AMP ligase, chrysobactin biosynthesis
- MbtH-like protein
- Enterobactin exporter EntS
- Nonribosomal peptide synthetase
- isochorismate synthase
- Dimodular nonribosomal peptide synthetase
- 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
Sequence:
MPAAQPSGFVATLLSSPQAGEEAWWQQVARLGTPLVEAQDSGRVRMTFLWRDPDGDERYSAIRRVYADINGVTDHHSTDPQSLERLPGTDVWHWSMAIEHDWRGSYSLIPIVAAQLPPVFSDDGQLRDEQQREWWCSLFPCAIADPLNRDQSWGEQLSAAHMPAAPSQQAWRAVDNGTALPPDAARLTVLDWKSEQLDNQRRIWLYTTGISDEPAQRPLCIVLDGQKWAEETPLFAALEAETAAGHLPPAVWLFIDAIDGETRCRELPCDAAFWLAVQDELLPQAARLAPFSDDPDRTVVSGQSYGGLAALYAGLHWPQRFGRVLTQSGSFWWPNLQFITDFDQRDTLEPGVLVTEVRQGGQTAWPLVIFQEAGRREADIAFVNQQMHEALVAAGHQVHQRVYAGGHDTLCWRGGLIDGFRWLLTGDDPQAASRD
Protein: Non-structural protein 1 (NS1) (A5A5U1)
Organism: Influenza A virus (strain A/Vietnam/1203/2004 H5N1)
Subcellular location: Host nucleus {ECO:0000256|RuleBase:RU362113}. Host cytoplasm {ECO:0000256|RuleBase:RU362113}.
Interaction partners:
Sequence:
MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGNTLGLDIETATRAGKQIVERILEGESDKALKMPASRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIKMDQAIMDKTIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTGEDVKNAIGVLIGGLEWNDNTVRVTETIQRFAWRNSDEDGRLPLPPNQKR
Protein: Cytochrome c oxidase subunit 2 (Q2F979)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000457}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU000457}.
Interaction partners:
Sequence:
MILRSLECRFLTIALCDAAEPWQLGSQDAATPMMQGIIDLHHDIFFFLILILVFVSRMLVRALWHFNEQTNPIPQRIVHGTTIEIIRTIFPSVILLFIAIPSFALLYSMDGVLVDPAITIKAIGHQWYRPYEYSDYNSSDEQSLTFDSYTIPEDDPELGQSRLLEVDNRVVVPAKTHLRMIVTPADVPHSWAVPSSGVKCDAVPGRSNLTSISVQREGVYYGQCSEICGTNHAFTPIVVEAVTLKDYADWVSNQLILQTN
Protein: FI20019p1 (Fimbrin, isoform C) (Q8IQZ8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLDANKDGFIDLHELKDALNQVGFKLAGYQVREMIDEYKGKQLTAFQGKLNLEEFEALCLDLKSKDVASTFKTVVSKKENLETLGGMSSISSEGTTHSVRLEEQLAFSDWINSNLGHDKDLQHLLPIDSEGKRLYLSIKDGILLCKIINHSCPDTIDERAINKKNLTVYREFENLTLALVSSQAIGCNIVNIDAHDLAKGKPHLVLGLLWQIIRIGLFSHITLDSCPGLAGLLFDNERLEDLMKMSPEAILLRWVNHHLERAGISRRCTNFQSDIVDSEIYSHLLKQIAGNDADVNLDALRESDLQSRAEIMLQQAAKLNCRSFLTPQDVVNGVYKLNLAFVANLFNNHPGLDKPEQIEGLESIEETREEKTYRNWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWSRVHKRFSPLRKFMEKLENCNYAVDLGKQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPIIEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQEDNLANAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMMALDYVPNMDSVDQNNHNSSANNSN
Protein: Symplekin (Q8MSU4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of a protein complex required for cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:18042462}. Note=Concentrates in the histone locus body. {ECO:0000269|PubMed:18042462}.
Interaction partners:
- LD24014p
- Factor interacting with poly
- Probable cleavage and polyadenylation specificity factor subunit 2
- polynucleotide adenylyltransferase
- Cleavage and polyadenylation specificity factor subunit 1
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Cleavage and polyadenylation specificity factor subunit 4
- Cleavage and polyadenylation specificity factor 73
- Cleavage stimulation factor 64 kD subunit
- Protein suppressor of forked
Sequence:
MDSIIGRSQFVSETANLFTDEKTATARAKVVDWCNELVIASPSTKCELLAKVQETVLGSCAELAEEFLESVLSLAHDSNMEVRKQVVAFVEQVCKVKVELLPHVINVVSMLLRDNSAQVIKRVIQACGSIYKNGLQYLCSLMEPGDSAEQAWNILSLIKAQILDMIDNENDGIRTNAIKFLEGVVVLQSFADEDSLKRDGDFSLADVPDHCTLFRREKLQEEGNNILDILLQFHGTTHISSVNLIACTSSLCTIAKMRPIFMGAVVEAFKQLNANLPPTLTDSQVSSVRKSLKMQLQTLLKNRGAFEFASTIRGMLVDLGSSTNEIQKLIPKMDKQEMARRQKRILENAAQSLAKRARLACEQQDQQQREMELDTEELERQKQKSTRVNEKFLAEHFRNPETVVTLVLEFLPSLPTEVPQKFLQEYTPIREMSIQQQVTNISRFFGEQLSEKRLGPGAATFSREPPMRVKKVQAIESTLTAMEVDEDAVQKLSEEEFQRKEEATKKLRETMERAKGEQTVIEKMKERAKTLKLQEITKPLPRNLKEKFLTDAVRRILNSERQCIKGGVSSKRRKLVTVIAATFPDNVRYGIMEFILEDIKQRIDLAFSWLFEEYSLLQGFTRHTYVKTENRPDHAYNELLNKLIFGIGERCDHKDKIILIRRVYLEAPILPEVSIGHLVQLSLDDEFSQHGLELIKDLAVLRPPRKNRFVRVLLNFSVHERLDLRDLAQAHLVSLYHVHKILPARIDEFALEWLKFIEQESPPAAVFSQDFGRPTEEPDWREDTTKVCFGLAFTLLPYKPEVYLQQICQVFVSTSAELKRTILRSLDIPIKKMGVESPTLLQLIEDCPKGMETLVIRIIYILTERVPSPHEELVRRVRDLYQNKVKDVRVMIPVLSGLTRSELISVLPKLIKLNPAVVKEVFNRLLGIGAEFAHQTMAMTPTDILVALHTIDTSVCDIKAIVKATSLCLAERDLYTQEVLMAVLQQLVEVTPLPTLMMRTTIQSLTLYPRLANFVMNLLQRLIIKQVWRQKVIWEGFLKTVQRLKPQSMPILLHLPPAQLVDALQQCPDLRPALSEYAESMQDEPMNGSGITQQVLDIISGKSVDVFVTDESGGYISAEHIKKEAPDPSEISVISTVPVLTSLVPLPVPPPIGSDLNQPLPPGED
Protein: Vomeronasal secretory protein 1 (Lipocalin-3) (Vomeronasal secretory protein I) (VNSP I) (Q62471)
Organism: Mus musculus (Mouse)
Function: Transport of lipophilic molecules, possible pheromone-carrier.
Subcellular location: Secreted.
Interaction partners:
- Epididymal-specific lipocalin-8
Sequence:
MRALLLIISFCLVAVLQAQDSSFLAFNNGNFSGKWFLKALVSEDDIPINKVSPMLILVLNNGDIELSITHMIYDQCLEVTTILEKTDVPGQYLAFEGKTHLQVQLSSVKGHYMLYCDGEIEGMRFLMTQLIGRDPQENLEALEEFKVFTQIKGLVAENLVILEQMEKCEPESFYELPSRPSE
Protein: Kinesin-like protein tea2 (Kinesin-like protein 4) (Tip elongation aberrant protein 2) (Q1MTQ1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Promotes microtubule growth, possibly through interactions with the microtubule end, and is important for establishing and maintaining polarized growth along the long axis of the cell. Acts as a kinesin motor protein that moves along microtubules and is required for proper localization of tea1 and tip1 to the cell tips and microtubules, respectively. ATPase activity stimulated via interaction with mal3.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:11018050, ECO:0000269|PubMed:15177031}. Note=Localized in large clusters at cell tips and also in punctate dots within the cell that are coincident with the ends of cytoplasmic microtubules.
Interaction partners:
- Tip elongation protein 1
- Microtubule integrity protein mal3
- Tip elongation aberrant protein 1
- Anaphase spindle elongation protein 1
- Kinesin-like protein cut7
- Kinetochore protein ndc80
- Kinetochore protein nuf2
- Tubulin alpha-2 chain
- Tip elongation aberrant protein 3
- Spindle pole body component alp14
Sequence:
MSSSSSKPVNTGLVTPRRYSTMTGIRTGPSQSGTGSIPYSPTSPLSRNFSNYSIPMLRSNSTQTNVNGPTAFDLGVTEKLMSPGTLDRYTRPALYPSKDLDYLKNEYVNYESTTSQQTNSKGLKESNFVGSGIITSIRIRPIGKNQGVWSHGKLSNDPYGREYIRQQTSTSSSTIQQEYLFNNVFGMESKNYDIYKRSVKSVVRNVFSGYNGIVFAYGMTGTGKTYSMQGTENEPGIIPLAMNDLFEMVENNSDDDTFQIRISYLEIYNERIRDLIGNSDEEPRIRENASGEVNVTPLTRVLVTSPEEVSQVIEQCNAIRKTAATDFNTYSSRSHAILQVFLIRNNPTAHTSQISSLSLVDLAGSERASAHHERRKEGAFINKSLLTLGTVISRLSAAANPSLTSNSGHIPYRESKLTRLLQQSLSGQSQISLLATISIESNHTMETTNTLKFASRAQNLPQDIRQAEAVTNVQAELASLHSALEKNAQEVEYYASLVKQLTSDLEERDTYIAMLEAERSQGTAISRARLRMEELLSDHNFEIADLRDELQDKEQIIYALRYAQKQRDIADFNQSLAKFPHKILKKNVTRGSRSSSDQFSNETKTEILPDDQQQSKKDSVTQETQLLS
Protein: Increasing suppression factor 1 (Mitochondrial biogenesis regulation protein 3) (P32488)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Could influence the NAM7/UPF1 function, possibly at the level of mRNA turnover. Participates in mitochondrial biogenesis.
Interaction partners:
- Uncharacterized protein YMR206W
Sequence:
MIASEIFERGVQDPFCQDCDYEDETDVQSFLGSNDLNDFVNSKLASFSFQNSSKSNNSHHSSSTNAGNTSRHIGNHTIGHHLRKIKTAPHHLYGFVPANSTNNSNEPIRPSPRRIRANSSTLIHQLSRQSTRQSSLGDAADSCFDHKCIKPRSRHSSCYGIPTHLYGLEKYVSSELDSLAVANDQSNDLTSPLTSVSTPASNSNSYLNLNSSSAAYPSSYLSNEKNNRLKLISHGKISSNNVPGHSGNLNHYHRERTPSNLRRESFSLLSNGSSSSPLQTRNNSYSNSLVKSPSNSSLNTSVASSNEESSPHTSNCLEERNPRRKSFIKLSLASSFSN
Protein: Putative mitochondrial import inner membrane translocase subunit Tim8 A-B (Q4FZG7)
Organism: Mus musculus (Mouse)
Function: Putative mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit Tim10
- Mitochondrial import inner membrane translocase subunit Tim13
- Mitochondrial import inner membrane translocase subunit Tim9
- Mitochondrial import inner membrane translocase subunit Tim10 B
- Mitochondrial import inner membrane translocase subunit Tim8 A
Sequence:
MESAWSSRGTSLGSSDPQLQRFMEAEVQKQRVQLLIHHMTELCWEKCMDKPGPRLDGRAELCLVNCVERFIDTSQFILNRLEQTQKARPLFSERLSD