wanglab/gogpt-training-data huggingface dataset:
Protein: LD32040p (Msb1l) (Q9VIT3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform D
- Inner centromere protein, isoform A
- What else, isoform A
- Cyclin-dependent kinase 1
- Serine/threonine-protein kinase polo
- Kinesin-like protein Klp61F
- Aurora kinase B
- Mitotic spindle assembly checkpoint protein MAD2A
- Protein claret segregational
- Cyclin-dependent kinases regulatory subunit
Sequence:
MGAKATKMEGEYLPDTPTLNKMRLASEKREQMEMTTPNREQNNALLDPRSPNGCRTPLTFLQASKPRVEEEEQHVTTSENAFSMLRKRLLKGFSLNDPRSPQLNRTPLVLDEVRSLNMDDTFADLFVDTRVGTAQRAVPASPPQVDLEESCDSFGTPPSAAHNNISLEIVSLPYDQEETLPCEQQLLPYQEPNLEQGQVKMATPPPEQQPHGDPRSPSLGVDRTPIIFCDDEEEEAREAQMLEHILETLTLNLSTGSSMASFVAGEEQLPEVPSNKHLERVRLGHKRRVPPRKPARANKPKIYVDQEEGSPVTGGSITPKTNSTPLSAQKRTPLSCVKNKPHLRSRSMEKDSKKNQIPPAQSFNDQLRIISGTEGFSGPVY
Protein: Protein AF-10 (ALL1-fused gene from chromosome 10 protein) (P55197)
Organism: Homo sapiens (Human)
Function: Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation.
Subcellular location: Nucleus {ECO:0000269|PubMed:10860745}.
Interaction partners:
- Histone-lysine N-methyltransferase, H3 lysine-79 specific
- Protein AF-9
- Protein ENL
- AF4/FMR2 family member 1
- Protein AF-17
- Phosphatidylinositol-binding clathrin assembly protein
- RNA polymerase II elongation factor ELL
- Afadin
- YEATS domain-containing protein 4
- Histone-lysine N-methyltransferase 2A
Sequence:
MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPEQHQAFLYQLMQHHHQQHHQPELQQLQIPGPTQIPINNLLAGTQAPPLHTATTNPFLTIHGDNASQKVARLSDKTGPVAQEKS
Protein: Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Protein underwhite) (Solute carrier family 45 member 2) (P58355)
Organism: Mus musculus (Mouse)
Function: Proton-associated glucose and sucrose transporter. May be able to transport also fructose. Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis. Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR.
Subcellular location: Melanosome membrane {ECO:0000269|PubMed:32966160}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- 5,6-dihydroxyindole-2-carboxylic acid oxidase
- Sodium/potassium/calcium exchanger 5
- P protein
- Tyrosinase
- G-protein coupled receptor 143
- L-dopachrome tautomerase
- Melanocyte protein PMEL
- Melanocyte-stimulating hormone receptor
- Melan-A
Sequence:
MSGSNGPTDTHTYQSLAEDCPFGSVEQPKRSTGRLVMHSMAMFGREFCYAVEAAYVTPVLLSVGLPKSLYSMVWLLSPILGFLLQPVVGSASDHCRARWGRRRPYILTLAIMMLLGMALYLNGDAVVSALVANPRQKLIWAISITMVGVVLFDFSADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYILGAIDWVHLDLGRLLGTEFQVMFFFSALVLILCFITHLCSIPEAPLRDAATDPPSQQDPQGSSLSASGMHEYGSIEKVKNGGADTEQPVQEWKNKKPSGQSQRTMSMKSLLRALVNMPSHYRCLCVSHLIGWTAFLSNMLFFTDFMGQIVYHGDPYGAHNSTEFLIYERGVEVGCWGLCINSVFSSVYSYFQKAMVSYIGLKGLYFMGYLLFGLGTGFIGLFPNVYSTLVLCSMFGVMSSTLYTVPFNLIAEYHREEEKEKGQEAPGGPDNQGRGKGVDCAALTCMVQLAQILVGGGLGFLVNMAGSVVVVVITASAVSLIGCCFVALFVRYVD
Protein: Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Malate dehydrogenase [quinone] cytochrome b560 subunit) (Succinate-ubiquinone oxidoreductase cytochrome B large subunit) (CYBL) (D0VWV4)
Organism: Sus scrofa (Pig)
Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:17480203}; Multi-pass membrane protein {ECO:0000269|PubMed:17480203}.
Interaction partners:
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- Fumarate hydratase, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Cytochrome c oxidase subunit 2
- Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
Sequence:
MAALLLRHVGRHCLRAHLSPQLCIRNAVPLGTTAKEEMERFWNKNLGSNRPLSPHITIYRWSLPMAMSICHRGTGIALSAGVSLFGLSALLLPGNFESHLELVKSLCLGPTLIYTAKFGIVFPLMYHTWNGIRHLIWDLGKGLTIPQLTQSGVVVLILTVLSSVGLAAM
Protein: Chaperone DnaJ-domain superfamily protein (Q0WQM3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DnaJ domain protein
Sequence:
MMSHGGGGGVSNGGGGDAERMLAQAEKLLLSGDLNGSKTYAIRACEADHSLVDHAELILAVADTLVAGESRIRGTTSDLPDWYAVLRLVRLTHNPELVATQYSRLAVLLNPSRNRYPYSEQAFRLISDAWYVLSDPSRKTLYDRELHLSQFGQLGQLGFQLFNQTPQSQSQSPQHHQQQSQSPQHPNQNQTVSFQNQQLPFQLHQPHFAQAVQTQSQSQQQRSQFDQQLLQEQQQASWRQQVGQEHSSGSSGDWKRPVEEVRLINLNNATERVQSSRRFAEPERPPSRSFEGSSHRTPSTELTWASKPTPVSEPVRHSELVPWQYSEPARQYQLSSRSSEAAQLSLLPSVSDSSHASQPTRSNQSHAVSKPQPVSKPHPPFPMSQPPPTSNPFPLSQPPSNSKPFPMSQSSQNSKPFPVSQSSQKSKPLLVSQSSQRSKPLPVSQSLQNSNPFPVSQPSSNSKPFPVSQPQPASNPFPVSQPRPNSQPFSMSQPSSTARPFPASQPPAASKSFPISQPPTTSKPFVSQPPNTSKPMPVSQPPTTSKPLPVSQPPPTFQSTCPSQPPAASSSLSPLPPVFNSTQSFQSPPVSTTPSAVPEASTIPSPPAPAPVAQPTHVFNQTPPPEQTPKSGAARTDSEPEVSSFWTTCPYCYVLYEYPIIYEESVLKCQTKSCRRAYQAVKVPSPPPVAEEDSYYCCWGFYPIGFSEVVTKIPVTGLHTKIPVSDLPKSAPKKPSPKVYYYDDEEEDDDSYIGSDPSEDDDDDDWLMNGTKRRKNVKQSKAKATTKPKRQKVIEVD
Protein: Calcium binding tyrosine phosphorylation regulated (J3KTE8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE
Protein: Rho-associated protein kinase (EC 2.7.11.1) (Q9U779)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MPAGRETVTKQRSMDVERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIPEKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKGFDGNHLPFIGFTYTGDYQLLSSDTVDAESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEALLERERGRSEALEQQDAGLRQQIELITKREAELQRIASEYEKDLALRQHNYKVAMQKVEQEIELRKKTEALLVETQRNLENEQKTRARDLNINDKVVSLEKQLLEMEQSYKTETENTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQKHKEELGQENAELQALVVQEKNLRSQLKEMHKEAENKMQTLINDIERTMCREQKAQEDNRALLEKISDLEKAHAGLDFELKAAQGRYQQEVKAHQETEKSRLVSREEANLQEVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLEGECRQESEKVAALQSQLDQEHSKRNALLSELSLHSSEVAHLRSRENQLQKELSTQREAKRRFEEDLTQLKSTHHEALANNRELQAQLEAEQCFSRLYKTQANENREESAERLSKIEDLEEERVSLKHQVQVAVARADSEALARSIAEETVADLEKEKTIKELELKDFVMKHRNEINAKEAALATLKEAENELHKKLGQKAAEYEDLVQQHKKQQEELALMRSSKDEEITKLLDKCKNEVLLKQVAVNKLAEVMNRRDSDLPKQKNKARSTAELRKKEKEMRRLQQELSQERDKFNQLLLKHQDLQQLCAEEQQLKQKMVMEIDCKATEIENLQSKLNETASLSSADNDPEDSQHSSLLSLTQDSVFEGWLSVPNKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLYAGEGASHRPDEQNQLDVSVLHGNCNEERPGTIVHKGHEFVHITYHMPTACEVCPKPLWHMFKPPAAYECKRCRNKIHKEHVDKHDPLAPCKLNHDPRSARDMLLLAATPEDQSLWVARLLKRIQKSGYKAASYNNNSTDGSKISPSQSTRSSYKPYAVNVQRSATLPANSSLK
Protein: BetaIV-spectrin sigma6-A (BetaIV-spectrin sigma6-B) (BetaIV-spectrin sigma6-C) (Q8VBX2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLMARDGTREDSHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKRLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQTAALPLEQASKELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQVAHDLDDELAWVQERLPLAMQTERGTGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGVLASLRSPEAEAVRRGQEQLQSAWTGLREAAERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETGTAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTAPPEPRPSASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELAACQELGRSLLLNKSAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPTELAAKAAPLLRPGGYDRGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPETSGKVEPAAPTAAALDTTDTPGTPAATEQVRPRSERQELADRAEELPRRRRSERQESVDQPEETARRRRPERQESADHEGPHSLTLGRYEQMERRRERRERRIERQESSEQETPTRGELVKGKATLADIVEQLQEKEAGPGIPAGVPSLPQPRELPPGRLPNGLEPPERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDANRKSSNRSWVSLYCVLSKGELGFYKDSKGPASGGTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAVANSVAEHAEIARWGQTLPTTSSTDEGNPKREGGERRASGRRK
Protein: Myosin-6 (AtMYA2) (Q9LKB9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in the tip growth of root hair cells. Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development. Targets the peroxisome through an interaction with RABC2A. Required for development of pavement cells, trichomes, and stigmatic papillae.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15792961, ECO:0000269|PubMed:17288617, ECO:0000269|PubMed:17500056}. Note=Colocalizes with peroxisome and cytoplasmic vesicles.
Interaction partners:
- Ras-related protein RABC2a
- Ras-related protein RABD1
- Myosin-binding protein 2
- Myosin-binding protein 1
- Myosin-binding protein 3
- Fimbrin-1
- WPP domain-interacting tail-anchored protein 2
Sequence:
MVANFNPSVGSFVWVEDPDEAWIDGEVVQVNGDEIKVLCTSGKHVVTKISNAYPKDVEAPASGVDDMTRLAYLHEPGVLQNLHSRYDINEIYTYTGSILIAVNPFRRLPHLYSSHMMAQYKGASLGELSPHPFAVADAAYRQMINDGVSQSILVSGESGAGKTESTKLLMRYLAYMGGRAAAEGRSVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDEKGRISGAAIRTYLLERSRVCQVSDPERNYHCFYMLCAAPQEDVKKFKLEEPKKYHYLNQSKCLELDSINDAEEYHATRRAMDVVGISTEEQDAIFSVVAAILHIGNIEFAKGEEIDSSIPKDDKSLFHLKTAAELLSCDEKALEDSLCKRIMVTRDETITKTLDPEAATLSRDALAKVMYSRLFDWLVDKINSSIGQDHDSKYLIGVLDIYGFESFKTNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEINWSYIEFVDNQDILDLIEKKPGGIIALLDEACMFPRSTHETFAQKLYQTFKTHKRFTKPKLARSDFTICHYAGDVTYQTELFLDKNKDYVIAEHQALLNSSSCSFVASLFPPMSDDSKQSKFSSIGTRFKQQLVSLLEILNTTEPHYIRCIKPNNLLKPGIFENENILQQLRCGGVMEAIRISCAGYPTRKHFDEFLARFGILAPEVLVKNSDDPAACKKLLDKVGLEGYQIGKTKVFLRAGQMADLDTRRTEVLGRSASIIQRKVRSYLAKKSFIVLRNSAKQIQSVCRGYLARSVYEGMRREAAALKIQRDLRRFLARKAYTELYSAAVSVQAGMRGMVARKELCFRRQTKAAIIIQTWCRGYLARLHYRKLKKAAITTQCAWRSKVARGELRKLKMAARETGALQAAKNKLEKQVEELTWRLQLEKRIRTDLEEAKKQESAKAQSSLEELQLKCKETEALLIKEREAAKKIAETAPIIKEIPVVDQELMDKITNENEKLKSMVSSLEMKIGETEKKLQETTKISQDRLNQALEAESKLVKLKTAMQRLEEKILDMEAEKKIMHQQTISTPVRTNLGHPPTAPVKNLENGHQTNLEKEFNEAEFTTPVDGKAGKSAAERQIMNVDALIDCVKDNIGFSNGKPVAAFTIYKCLLHWKCFESEKTNVFDRLIQMIGSAIENEDDNSHLAYWLTSTSALLFLLQKSLKTNGSGATQSKKPPASTSLFGRMAMSFRSSPASGNLAAAAEAAALAVVRPVEAKYPALLFKQQLAAYVEKMFGMVRDNLKRELSTLLSLCIQAPRSSKGGMLRSGRSFGKDSPAVHWQSIIDGLNSLLVTLKENHVPLVLIQKIYSQTFSYINVQLFNSLLLRKECCTFSNGEFVKSGLAELELWCCQAKEYSGPSWEELKHIRQAVGFLVIHQKYRISYDEIANDLCPVLSVQQLYRICTLYWDDSYNTRSVSQEVISSMRTLMTEESNDADSDSFLLDDDSSIPFSIDDISSSMEEKDFVGIKPAEELLENPAFVFLH
Protein: BCL9 like (A0A087WZX0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNVGSKGVGAGNHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRDRSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCNVADPAMAAPQLGPGQTTQLPLSESSVPGAPHGPPPGLRPDAPGGGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPPPPQQPPTAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPPGGDMGQQMNMMIQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGGMMVRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQSMPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYSQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF
Protein: Diheme cytochrome c5 peroxidase CcpA (EC 1.11.1.5) (Q8EF24)
Organism: Shewanella oneidensis (strain ATCC 700550 / JCM 31522 / CIP 106686 / LMG 19005 / NCIMB 14063 / MR-1)
Subcellular location: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
Interaction partners:
- Periplasmic monoheme cytochrome c5 ScyA
- SoxA-like diheme cytochrome c
- Fumarate reductase
- Flavocytochrome c heme submit
- Monoheme cytochrome c
Sequence:
MTKLTAIAITLTAIFASSYAVAAEPIEVITPAKITEPEKVELGKMLFFEPRLSKSGFISCNSCHNLSTGGVDALPTSIGHHWQEGPINSPTVLNADFMLAQFWDGRASNLKEQAAGPIANPKEMGFTHELATETIASMPAYRARFAKVYGDEKVDIDRLTDAIAAFEKTLVTPNSPFDQYLLGKQDAISGDAKAGYQLFKDKGCVSCHNGPAVGGTMFMKMGLIKPFHTNNPAEGRKGVTGKDADKFVFKVPTLRNIELTYPYFHDGSVWTLEEAVNTMADIQLGQKLTEKETKEMVAFLNSLTGEQPQISLPILPPSNKETPRPVPFATGAK
Protein: Protein IRX15-LIKE (Q9FH92)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for xylan biosynthesis, but not directly involved in catalyzing the addition of sugars to the growing polymer.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Also located in an unknown intracellular compartment that may have some role in the transport of cell wall polysaccharides into the cell wall. {ECO:0000269|PubMed:21251108}.
Interaction partners:
- Probable beta-1,4-xylosyltransferase IRX10
- Probable galacturonosyltransferase 12
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 2
- Beta-1,4-xylosyltransferase IRX9
- Probable galacturonosyltransferase-like 1
- Probable beta-1,4-xylosyltransferase IRX14H
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 1
- Beta-1,4-xylosyltransferase IRX14
- Protein REDUCED WALL ACETYLATION 3
- Probable beta-1,4-xylosyltransferase IRX10L
Sequence:
MKSGGNTNTKLILVHPYIQKQTSTNRLWLLAFVSFFTIAFLLTLLYTTDSIISSKNNSATVSSAVNSAVTTATISQLPTTAINAMLHYASRSNDSYHMSYGEMKSISDVLRRCSPPCNLLVFGLTHETLLWKSLNHNGRTVFIEENRYYAAYFEEIHPEIEVFDVQYTTKAREARELVSAVKEAARNECRPVQNLLFSDCKLGLNDLPNHVYDVDWDVILVDGPRGDGGDVPGRMSSIFTAAVLARSKKGGNPKTHVFVHDYYRDVERLCGDEFLCRENLVESNDLLAHYVLEKMDKNSTQFCRGRKKKRSVSSPSA
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q7SYN3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MENLKADPEELFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLEGNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIVRFAKKTSYLTELIDKYKRWKAEQSRAESSSDESDSEPDGQASGGNDFGNDDWIFTIREKDPKKLQNGASLVGEEKPNKRPLSQSLSTVITPVLTELKEGAGEAAAATTVKPEVLEQLGEAIFLAEEAYPGISDVMVTQLIQRLQRFSRARTSSSSHQ
Protein: Small COPII coat GTPase SAR1A (EC 3.6.5.2) (COPII-associated small GTPase) (Secretion-associated Ras-related GTPase 1A) (Q9NR31)
Organism: Homo sapiens (Human)
Function: Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23433038, ECO:0000269|PubMed:32358066}; Peripheral membrane protein {ECO:0000305|PubMed:23433038, ECO:0000305|PubMed:32358066}. Golgi apparatus, Golgi stack membrane {ECO:0000305|PubMed:34290409}; Peripheral membrane protein {ECO:0000305|PubMed:34290409}. Cytoplasm, cytosol {ECO:0000269|PubMed:34290409}. Lysosome membrane {ECO:0000305|PubMed:34290409}. Note=Active at endoplasmic reticulum exit sites (ERES) where it inserts into the membrane and recruits the remainder of the coat protein complex II/COPII (PubMed:23433038, PubMed:32358066). Upon leucine deprivation, associates with lysosomal membranes to repress TORC1 signaling (Probable). {ECO:0000269|PubMed:23433038, ECO:0000269|PubMed:32358066, ECO:0000305|PubMed:34290409}.
Interaction partners:
- Protein transport protein Sec23B
- Guanine nucleotide-exchange factor SEC12
- Protein SEC13 homolog
- Protein transport protein Sec31A
- Protein transport protein Sec24B
- Protein transport protein Sec24A
- Protein transport protein Sec23A
- Protein transport protein Sec24C
- Protein transport protein Sec24D
- Protein transport protein Sec31B
Sequence:
MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID
Protein: V-set and transmembrane domain-containing protein 2A (Q8TAG5)
Organism: Homo sapiens (Human)
Function: Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q8R0A6}. Note=Secreted by adipose precursor cells (By similarity). Not detected in the nucleus (PubMed:28052263). {ECO:0000250|UniProtKB:Q8R0A6}.
Interaction partners:
Sequence:
MMGIFLVYVGFVFFSVLYVQQGLSSQAKFTEFPRNVTATEGQNVEMSCAFQSGSASVYLEIQWWFLRGPEDLDPGAEGAGAQVELLPDRDPDSDGTKISTVKVQGNDISHKLQISKVRKKDEGLYECRVTDANYGELQEHKAQAYLKVNANSHARRMQAFEASPMWLQDMKPRKNVSAAIPSSIHGSANQRTHSTSSPQVVAKIPKQSPQSGARIATSHGLSVLLLVCGFVKGALL
Protein: Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) (P00958)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the attachment of methionine to tRNA(Met) in a two-step reaction: methionine is first activated by ATP to form Met-AMP and then transferred to the acceptor end of tRNA(Met).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11726524}. Note=Largely excluded from the nucleus.
Interaction partners:
- Isoleucine--tRNA ligase, cytoplasmic
- Glutamate--tRNA ligase, cytoplasmic
- tRNA-aminoacylation cofactor ARC1
- Putative proline--tRNA ligase YHR020W
- Leucine--tRNA ligase, cytoplasmic
- Glutamine--tRNA ligase
- Lysine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase, mitochondrial
- Aspartate--tRNA ligase, cytoplasmic
- Glutamate--tRNA ligase, mitochondrial
Sequence:
MSFLISFDKSKKHPAHLQLANNLKIALALEYASKNLKPEVDNDNAAMELRNTKEPFLLFDANAILRYVMDDFEGQTSDKYQFALASLQNLLYHKELPQQHVEVLTNKAIENYLVELKEPLTTTDLILFANVYALNSSLVHSKFPELPSKVHNAVALAKKHVPRDSSSFKNIGAVKIQADLTVKPKDSEILPKPNERNILITSALPYVNNVPHLGNIIGSVLSADIFARYCKGRNYNALFICGTDEYGTATETKALEEGVTPRQLCDKYHKIHSDVYKWFQIGFDYFGRTTTDKQTEIAQHIFTKLNSNGYLEEQSMKQLYCPVHNSYLADRYVEGECPKCHYDDARGDQCDKCGALLDPFELINPRCKLDDASPEPKYSDHIFLSLDKLESQISEWVEKASEEGNWSKNSKTITQSWLKDGLKPRCITRDLVWGTPVPLEKYKDKVLYVWFDATIGYVSITSNYTKEWKQWWNNPEHVSLYQFMGKDNVPFHTVVFPGSQLGTEENWTMLHHLNTTEYLQYENGKFSKSRGVGVFGNNAQDSGISPSVWRYYLASVRPESSDSHFSWDDFVARNNSELLANLGNFVNRLIKFVNAKYNGVVPKFDPKKVSNYDGLVKDINEILSNYVKEMELGHERRGLEIAMSLSARGNQFLQENKLDNTLFSQSPEKSDAVVAVGLNIIYAVSSIITPYMPEIGEKINKMLNAPALKIDDRFHLAILEGHNINKAEYLFQRIDEKKIDEWRAKYGGQQV
Protein: Low-density lipoprotein receptor-related protein 11 (LRP-11) (Q86VZ4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MASVAQESAGSQRRLPPRHGALRGLLLLCLWLPSGRAALPPAAPLSELHAQLSGVEQLLEEFRRQLQQERPQEELELELRAGGGPQEDCPGPGSGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVAACCSEPRCSVAVVELPRRPAPPAAVLGCYLFNCTARGRNVCKFALHSGYSSYSLSRAPDGAALATARASPRQEKDAPPLSKAGQDVVLHLPTDGVVLDGRESTDDHAIVQYEWALLQGDPSVDMKVPQSGTLKLSHLQEGTYTFQLTVTDTAGQRSSDNVSVTVLRAAYSTGGCLHTCSRYHFFCDDGCCIDITLACDGVQQCPDGSDEDFCQNLGLDRKMVTHTAASPALPRTTGPSEDAGGDSLVEKSQKATAPNKPPALSNTEKRNHSAFWGPESQIIPVMPDSSSSGKNRKEESYIFESKGDGGGGEHPAPETGAVLPLALGLAITALLLLMVACRLRLVKQKLKKARPITSEESDYLINGMYL
Protein: MifR (Q9HT62)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- C4-dicarboxylate transport sensor protein DctB
- C4-dicarboxylate transport sensor protein DctB
- C4-dicarboxylate transport transcriptional regulatory protein DctD
- Probable MFS dicarboxylate transporter
- histidine kinase
- RNA polymerase sigma-54 factor
- C4-dicarboxylate transport sensor protein DctB
- AB hydrolase-1 domain-containing protein
Sequence:
MSDQVIFVDDEATIREAVQQWLELSGFEVRLCLRAEECLGALDKSFAGVVISDVRMPGMDGLQLLANLQAVDRDLPVIMVTGHGDVPMAVEAMRQGAYDFIEKPFTPERLLGSLRRALEKRRLVLENRRLKEQASLKDQVDARLLGVSKPMEALRRQVLALAPTPVNVLIRGETGSGKELVARCLHDFGPRADKPFVALNCAAIPEQLFESELFGHESGAFTGAQGKRIGKLEHAHGGTLFLDEIESMPLAQQVKLLRVLQEQQLERLGSNQSIHVDLRVIAATKPDLLAEARAGRFREDLVYRLNVAELRLPPIRERREDIPLLFEHFASVASQRLGREPQPAAPAELARLMAHDWPGNVRELANAAERHVLGLERGDAEEGGGLTSGLAERMEAFEAECLRQALGQCRGDIKAVMELLQLPRRTLNEKMLRHGLSRSDFVGEEPA