wanglab/gogpt-training-data huggingface dataset:
Protein: BCL-6 corepressor (BCL6 corepressor) (Q6W2J8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MVDASTTCRMNPLSALGIDRTSLMRESLRVHGGMVYPPGIQTLQSEKGYVGDRIPNLLYKPDVSLDSRKTANSFVGLYKSSPPGIQKPLIVPGAGADTLGLDRRVVPGDKPPELSLNGGSSYLRVPSWMSPYHETGMYPFLDSSKYAALNMYKASILSQPPPYLPQHLAYQSLCAGAGGSVAGTERLFYMPTYPPAPISSPLAPPLRIPPATVAPTTLSPMMHHQDKTVQSIGPRIHHEPSAFGQQTIHQHTQPHHQSPIDRQHSSSGNSSSNSKSIRTSSSKNLSSTSSIVSSSAGISSCTSSIVSVDSCPSLVMQPPRPTPRPPQPPAAPPPPLMDSTMEFQKPLYRSPSSSSSSSPSVSHPVYISSASQELRSPIRSSGQKPKAKEATMESTRGMGNERKGSSSPVKTSSDKSPQQGPITKDPADKPLDLSAKIMEFEGHTNGYPSKLEALAKLGYSPAARYGLPPNRELLKETLSPSSSAVSTSKTPERPEIISTLPSSWVVPSPTQTISSEASQNKGSSIIKNKNLENVVPQSRSSSCPKVDDQNNGSVSSSAPIIITSTSRPSSVSPSPKMNGDWAKSVPTPPEKTPINNHSGSHSSATKPSKTAKKTETPDIGFKPQQSHLENGHTPSHLYMQQGETYLSPGLAYSSRYLSYPVPESLSLSHLQLSGKGPVYPHPVLLGANSLYSTRLPPKPGIPFGIPPNHAEYLTYHDSQEMVHPLMSPHLPLDHKVTERLDLRPRTLDKTWHHDEPPYKRQSITDIDPDYKSEKESERQEVLGSKSLSKPHTVNKDEIVCIDLVQDDTDGSPEPDKHSTIDAKCKEPAKPVGSGTGMGNESGSNSEGKEPELMQILRSGQPAVSWPTDSEQRAEVCSPPRPHKQSDSPLHSQSEESSSEHSPLPDMLEEQTLRCARTSGERARADGAEFRVDRHHTNRQYVDLGKDGLEDTESHEDEEEGHGCSKGKRSSLAKRIANSSGYVGDRFKCVTTELYADSSKLSREQRALQRAMMRFSELELKEKEGCVSSAAPGLGREQERERELAESQHGAGDWERSQPSSRPSAALSALSDSTEQRNGTTPACANNRVPVLQRCGLPADVLQPHRTEEKRARDVKGEEEGSVGTATGRKRALGLEHSQGHPDCTHTTEERDGERPTRGEEDNGIASKRARLISDVWPQPSEQEVKKLKVRIELTGLRLSKPRHLHNLQELWDRQGQLNHDRPQFGATNLGLPPTSKASIPPLQTTRREKLDPCTPEVPRVAHGVPAVDRKVKTNGIEEKGLKRKAEVERGWTKEQLEYAESNTAIPALSDSFCSDSIRKFSSAVPPHHLSDKRQRLKEHRKSVGSSSPSPDPDCTFPGRLRRHGDPEKPKGKRQCKTKHLSQQERRMLLQSTNQECPELSPAHQHKVVKCSAQKRPALLSNYESSPIKPHPPSPAYQPAASPTPPCAVADVPVPPLAPAPPVSAEPPVNRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKVCDVNHRDNAGYCALHEACSRGWLSIVQHLLEHGADINCSAQDGTRPLHDAVENDHLDVVRLLLSYGADPTLATYSGRGLLKMTHSDIMECFLSDYFADLQGRVDDDPSVYWEFYGSAVCEPADDSSGYDILANPPGPGEDEDEQRDVFEFEFSDRPLLPCYNIQVSLSQGPRNWLLLSDVLKRLKMSARTFRATFTHIEVVTIAEAEFYKQASLSQLFSCPEELEGFMPDSKELLDLVEISGELVALLGSSIECLDDRWEPASRPRS
Protein: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (Q5GA10)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MASSVGNVADSTGLAELAHREYQSGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINALHKPAYEHPKDLKASSGRLRVGYISSDFGNHPTSHLMQSIPGMHNSEKFEVFCYALSPDDGTNFRVKVMAEAHHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLAYPGTSGAPFMDYIVSDKATSPIEVAEQYSEKLAYMPNTFFIGDHANMFPHLKKKAVIDFKSNGHIFDNRIVLNGIDLKAFLESLPDVKVVKMECDGQEVADSNGALSMPIIPMNTAAEAIINMINQGQIQVTINGFTVSNGLATTQINNKAATGEEVPRTIVVTTRSQYGLPEDSIVYCNFNQLYKIDPPTLQMWANILKRVPNSVIWLLRFPAVGEPNIQQYAQNLGLPASRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCPELIAQSRQEYEDVAVKLGTDMEFLKKVRARVWKQRICSPLFNTKQYTMDLEKLYLQMWENHASGGKPDHLVKMQSLETSEST
Protein: CG5273 (RE67565p) (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform C) (Q9W5D6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform A
Sequence:
MMASSGGACSPFAYVAWALFALLLTHGGDNVVDARRNQGNQRKTSSSSSSSNYGHVTQPSYNTNGHAAGNSHADVAKLSYPNYNSQPNRPMAAGSSGSPGSAPQPGWNVPQGPPPAYSASNPAGGARPNMHEPPPAYHAPNYGAAPPNYGAATGSNVHQPQYSGVPAGATYYPAAGPGSGYSPNIPAGATYYPSAGHVPMGGGYHPAAAPPPGATYYQAGSALPPGATYYSAPPQQSSSGLGFGTGLLAGGLGGALLGHALTPSGGSSSSQPVAAAPAAGQDRIIIINNGVPVNASDGTTVINAAGVAAAPGAVPAAPVPSSNTTQDAQQPAVPMAPMPFNPETSNMTAPDPAAPPPPGGIICVPTKVNETDPADSTKMIEVEKIACYPAPPPPAASAGEGPAPLAPMAADQPGSQQVQQVQQAQDVAAPIQASVRSHTGGARALEGLTMRTLLLVLMSGVVAKRLAGF
Protein: Odorant receptor 49a (Q9V6A9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. Involved in the behavioral responses to butanol and 2-heptanone.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Odorant receptor 56a
- Odorant receptor 30a
- Odorant receptor 74a
Sequence:
MEKLRSYEDFIFMANMMFKTLGYDLFHTPKPWWRYLLVRGYFVLCTISNFYEASMVTTRIIEWESLAGSPSKIMRQGLHFFYMLSSQLKFITFMINRKRLLQLSHRLKELYPHKEQNQRKYEVNKYYLSCSTRNVLYVYYFVMVVMALEPLVQSCIMYLIGFGKADFTYKRIFPTRLTFDSEKPLGYVLAYVIDFTYSQFIVNVSLGTDLWMMCVSSQISMHLGYLANMLASIRPSPETEQQDCDFLASIIKRHQLMIRLQKDVNYVFGLLLASNLFTTSCLLCCMAYYTVVEGFNWEGISYMMLFASVAAQFYVVSSHGQMLIDLSTNLAKAAFESKWYEGSLRYKKEILILMAQAQRPLEISARGVIIISLDTFKILMTITYRFFAVIRQTVEK
Protein: Inner membrane protein ALBINO3, chloroplastic (Q8LBP4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the insertion of some light harvesting chlorophyll-binding proteins (LHCP) into the chloroplast thylakoid membrane. Required for the insertion of LHCB1, LHCB4.1 and LHCB5 proteins into thylakoid membrane, while it is not required for insertion of proteins PsbX, PsbW and PsbY.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:12217076, ECO:0000269|PubMed:9165749}; Multi-pass membrane protein {ECO:0000269|PubMed:12217076, ECO:0000269|PubMed:9165749}.
Interaction partners:
- Preprotein translocase subunit SCY1, chloroplastic
- Signal recognition particle 43 kDa protein, chloroplastic
- Cell division protein FtsY homolog, chloroplastic
- Signal recognition particle subunit SRP54, chloroplastic
- Sec-independent protein translocase protein TATA, chloroplastic
- Membrane-associated protein VIPP1, chloroplastic
- Thylakoid membrane protein TERC, chloroplastic
- Nucleoid-associated protein At2g24020, chloroplastic
- Protein LPA3
- Photosystem II CP43 reaction center protein
Sequence:
MARVLVSSPSSFFGSPLIKPSSSLRHSGVGGGGTAQFLPYRSNNNKLFTTSTTVRFSLNEIPPFHGLDSSVDIGAIFTRAESLLYTIADAAVVGADSVVTTDSSAVQKSGGWFGFISDAMELVLKILKDGLSAVHVPYAYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALSNVANEGLFTEGFFWIPSLGGPTSIAARQSGSGISWLFPFVDGHPPLGWYDTVAYLVLPVLLIASQYVSMEIMKPPQTDDPAQKNTLLVFKFLPLMIGYFALSVPSGLSIYWLTNNVLSTAQQVYLRKLGGAKPNMDENASKIISAGRAKRSIAQPDDAGERFRQLKEQEKRSKKNKAVAKDTVELVEESQSESEEGSDDEEEEAREGALASSTTSKPLPEVGQRRSKRSKRKRTV
Protein: ARM repeat superfamily protein (F4IYK3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Snurportin-1
- Importin subunit beta-1
- ARM repeat superfamily protein
- Ribosomal RNA-processing protein 8
- GTP-binding nuclear protein Ran-2
- GTP-binding nuclear protein Ran-3
- GTP-binding nuclear protein Ran-4
- GTP-binding nuclear protein Ran-1
- Nuclear cap-binding protein subunit 2
- Nuclear/nucleolar GTPase 2
Sequence:
MAMEITQFLLAAQSADARVRTEAEASLRQFQEQNLPLFLLSLSFELENNDKPAESRRLAGILLKNSLDAKDSATKDHLVKQWFAIDVALKSQIKDRLLRTLGSSALEARHTSAQVIAKVASIEIPQKQWPELVGSLLNNMTQQGSPAHLKQSTLETLGYVCEEISHHDLVQDEVNSVLTAVVQGMNQSENTAEVRLAATKALLNALDFSQTNFENEMERNYIMKMVCETACSKEAEIRQAAFECLVSIASTYYEVLEHYIQTLFELTSNAVKGDEESVALQAIEFWSSICDEEIDRQEYDSPDSGDSSPPHSCFIEKALPHLVQMLLETLLKQEEDQDHDDDVWNISMAGGTCLGLVARTVGDGVVPLVMPFVEKNISSPDWRSREAATYAFGSILEGPTIDKLAPMVAAGLEFLLNATKDQNNHVRDTTAWTLSRIFEFLHXPDSGFSVISPENLPRIVSVLLESIKDVPNVAEKVCGAIYNLAQGYEDSGASSSLLSPYLTEIITHLLAAAERTDGAESKLRGAAYETLNEVVRCSNLSEASSIIAHLLPAIMKKLAETMDLPIISTDDREKQAELQASLCGVLQVIIQKLSSRDDMKPIIVQNADDIMRLFLRVFGCHSSSVHEEAMLAIGALAYATGTEFVKYMPELFKYLQMGLQNFEEYQVCSITVGVIGDICRALDEKILPFCDQIMGLLIQNLQSGALHRSVKPPIFSCFGDIALAIGAHFERYVAPAVQIMQGAAQVCAQMDTLDEELMDYANQLRRSIFEAYSGILQGFKDAKAELMMPYAQHLLQFVELVSKDSLRDESVTKAAVAAMGDLADVVGENTKQLFQNFTFCDEFLNECLESEDEDLKVTARWTQGMIARLVL
Protein: Zygote arrest protein 1 (Oocyte-specific maternal effect factor) (Q80SU3)
Organism: Mus musculus (Mouse)
Function: mRNA-binding protein that mediates formation of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes. MARDO assembly around mitochondria is directed by an increase in mitochondrial membrane potential during oocyte growth. Promotes formation of MARDO phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs. Maternal mRNAs stored in the MARDO are translationally repressed. Essential for female fertility and oocyte-to-embryo transition by coordinating maternal mRNA storage, translation and degradation.
Subcellular location: Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000269|PubMed:31598710, ECO:0000269|PubMed:36264786}. Cytoplasm {ECO:0000269|PubMed:12539046}. Note=Specifically localizes to MARDO (mitochondria-associated ribonucleoprotein domain), a mitochondria-associated membraneless compartment that stores mRNAs in oocytes. {ECO:0000269|PubMed:36264786}.
Interaction partners:
- Growth/differentiation factor 9
- NACHT, LRR and PYD domains-containing protein 5
Sequence:
MFPASTFHPCPHPYPQATKAGDGWRFGARGCRPAPPSFLPGYRQLMAAEYVDSHQRAQLMALLSRMGPRSVSSRDAAVQVNPRRDASVQCSLGRRTLQPAGCRASPDARSGSCQPRGHAGAGRSPRSWQTVAPFSSVTFCGLSSSLEVAGGRQTPTKGEGSPASSGTREPEPREVAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEDRNSVAAMQSEPGSEEPCPAAEMAQDPGDSDAPRDQASPQSTEQDKERLRFQFLEQKYGYYHCKDCKIRWESAYVWCVQGTSKVYFKQFCRVCEKSYNPYRVEDITCQSCKRTRCACPVRLRHVDPKRPHRQDLCGRCKDKRLSCDSTFSFKYII
Protein: RNA polymerase-binding protein RbpA (P9WHJ5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Binds to RNA polymerase (RNAP), stimulating and stabilizing the formation of stable RNAP promoter complexes up to 2-fold from principal sigma factor SigA-dependent but not alternative sigma factor SigF-dependent promoters. Increases the affinity of core RNAP for SigA, increasing the transcriptional activity of RNAP. Unlike the case in M.smegmatis or S.coelicolor, has no effect on rifampicin inhibition of transcription. Has no effect on E.coli RNAP.
Interaction partners:
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit omega
- RNA polymerase sigma factor SigA
- RNA polymerase-binding transcription factor CarD
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit beta'
- RNA polymerase sigma factor SigB
- Protein PafC
- Probable transcriptional regulator WhiB7
- Protein PafB
Sequence:
MADRVLRGSRLGAVSYETDRNHDLAPRQIARYRTDNGEEFEVPFADDAEIPGTWLCRNGMEGTLIEGDLPEPKKVKPPRTHWDMLLERRSIEELEELLKERLELIRSRRRG
Protein: Cyclin-D1-binding protein 1 (Grap2 and cyclin-D-interacting protein) (Human homolog of Maid) (O95273)
Organism: Homo sapiens (Human)
Function: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Pre-mRNA-splicing factor SYF2
- GRB2-related adapter protein 2
- TCF3 fusion partner
- G1/S-specific cyclin-D1
Sequence:
MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
Protein: JmjC domain-containing protein (Q57VR2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPNEKAQTLTVAEAFAETSKALQQFNIERIRVDGLSRGNACDEEKFRMLTEQEFMREFVFHSRPCIIVGALCDWPALQRWRDDRYLFDLDEKLPMVYEKERTSKGNGEINENDSFHEDEEIVTESDAEDSKNGTSNNEAESQGTLGPRRVTVALTPNGRADAVTYVTYNAVKNESQVHDKLEGKSDFVVTEKLFMSAAELRVTLPELYRLLRANPLVPPLKSQFVDLRRPQRSIAYAQMQNNCLAEEYQHLHADIDTALDRFGTRVFGGKREAANIWLGTPASVSSMHQDWVENLYAVVRGVKEFILVPPWEGVFVPKPELPAAAFTLKAAANCKEGEEEYIFSDSPTRDGTSVPWMDVELTPAAVDDPLHIKEELRDKLHPLIAYVQPGEVLYLPALWLHRVAQHADSEDSRVIEEASTEEIAKVSRHDQKHSAPLPLIAAVNYWYDMSFTNPAVVMLREFGLLL
Protein: Uncharacterized protein (G5EAY7)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Calcium-channel protein CCH1
- mitogen-activated protein kinase kinase
- MADS-box domain-containing protein
- Transcription factor
- Response regulatory domain-containing protein
- MAP kinase kinase
Sequence:
MQRQNAPAQSRFGARVSVTILLAVLISAFATGTDLGPLTSDYGQGRLLAKDDTLGGFPYLLGSFSGLGIDREGDRAREPQGLDILNRASDDRRSLGNNRFGESEILMGELQQWLFVPDSTAGNSSDAQSDNISKRASTAVYVSLTICSAPILNESISNTAQALPQLAVYVSTSDSLQDPGPHHKSDSGQTVYHSSEGYMSATVSATSEVYIAVAAPSNGNFSGSYSYQLAVSTEDFFHNVDDRAALLSFNDSGSETALLTTVSPADEILTEEQRKQWENNTTVYKLFVNNANSTIGSGLSRSYCALAQHSQASNGHNVEASMSRRKSDDSTFQEQFYVTGLNRSSTYVGILAMGNTTEFGNGIVGGGGKVWKAKKFSTKSDGNCDVIYDLDFCSDVAHSVPSNPSMNMSEVRAKYDNYAANLYRNFNFSLQQIQCNTSNETIYSMAVSCDDCAAAYKSWLCAVTIPRCDDYSSTSNRTAVMVRNAAQPFPNGTEITNQTLRDSPITNRPRNSGLIDTEINPGPYKEVLPNVSFCHNLVRSCPMSLGFSCPSGKYLTYSYDTSAAPSGRISNPLWAVIMVYFTIVMVF
Protein: Voltage-dependent calcium channel alpha13 subunit (Q963J1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
EIVKYIAHLWRRFKRRMLKKYRLYKYQRQQRKEGLLPNADNLTFSPSRIKCHHPKCPKYSNRKPSSIQDQMITVMVPLNSASNNINNNNNNNSNSSNHNGSGNHTAAGGGNNNNNNNNNNAASCTTVALVNGINGSAASVTMSSAHHQQHQLLQHQQQQHQNQQQQQQQQQHSSSDNTEQSLAPDGLPRSSSLKKSTAHHQLKPEGSAAEQKTILLKFPQQMIDSEQLILQLGNLGKSHPCTSGFLSPPTSASRRPSVMFNEYVLLHTPPALNADPATAGTTTTVAPTVATVAGTAAAAAAAAATGSGSGNNNHQNGGASGGAGTGGTTEKSNIFSTEKMTQAGDGSIWQVNLPQTIGTIANPYADCSELGIHDAMTCQELLAFSVAFSAALPTGQSTLESFYTSLARCDPHTAEALRAHHKPRSVPTGQNQTTPGAEGATVMVASTAGDTGQTLQPSTVSAVVGGTIDSHAANHRRKEHHQQSHHHHNNNNTTSHSRNYRSRQGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIE
Protein: ATPase family AAA domain-containing protein 3C (Q5T2N8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSKDALNLAQMQEQTLQLEQQSKLKQLVNEDLRKQEESVQKHHQTFLESIRAAGTLFGEGFRAFVTDRDKVTATVAGLTLLAVGVYSAKNATAVTGRYIEARLGKPSLVRETSRITVLEALRHPIQQVSRRLLSRPQDVLEGVVLSPSLEARVRDIAIMTRNIKKNRGLYRHILLYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLYRTGQHSNKFMLILASCHPEQFDWAINACIDVMVHFDLPGQEERARLVRMYLNEYVLKPATEGKRRLKLAQFDYGRKCLEIARLTEGMSCRKIAQLAVSWQATAYASKDGVLTEAMMDACVQDFVQQHQQMMRWLKGERPGPEDEQPSS
Protein: Membrane-spanning 4-domains subfamily A member 8 (Four-span transmembrane protein 4) (Membrane-spanning 4-domains subfamily A member 8B) (Q9BY19)
Organism: Homo sapiens (Human)
Function: May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Membrane-spanning 4-domains subfamily A member 6E
- Putative membrane-spanning 4-domains subfamily A member 4E
Sequence:
MNSMTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQPVQKALKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPPSYSSEIQANK
Protein: Meiotically up-regulated gene 94 protein (O42647)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MDFNKIGDENVVFQIFKLEMLIMSEFPSFIEEKDKLLCLNVLANLLGGIFENEDKIIPNYKEAVIAALFERLLLSSNQKSTSKSNQMIKLLNNSLAHNNGLPSQRCNHDSKLVYMSLVQNNGLPGQRSNYVCCPLCMEQHCIELLTYQLFAKWRNFPRIDFSPVLQGNRGPRFFYTCFLCNSTFLASA
Protein: ATP synthase subunit beta (EC 7.1.2.2) (H0YH81)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
XFVGRVAAAPASGALRRLTPSASLPPAQLLLRAAPTAVHPGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQ
Protein: Sister chromatid cohesion protein PDS5 homolog A (Q6A026)
Organism: Mus musculus (Mouse)
Function: Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q29RF7}. Note=Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase (By similarity). {ECO:0000250|UniProtKB:Q29RF7}.
Interaction partners:
- Wings apart-like protein homolog
- Structural maintenance of chromosomes protein 3
- Nipped-B-like protein
- Structural maintenance of chromosomes protein 1A
- Cohesin subunit SA-2
- Double-strand-break repair protein rad21 homolog
- Sororin
- Cohesin subunit SA-1
- MAU2 chromatid cohesion factor homolog
- N-acetyltransferase ESCO2
Sequence:
MDFTQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNTKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPQLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDSAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVYLLRLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRKPYVRSAGTETGSNINANSELSPSAGSRSREQSSEASETGVSENEENPVRIISVTPVKNIDTVKNKEINSDQSTQGNISSDRGKKRIVTAAGAENIQKPDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPVSKGRKRAAGSQESLEAGNAKAPKLQDGAKKAVPAERQIDLQR
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (Q4WCD2)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
- Ubiquitin-protein ligase Sel1/Ubx2, putative
- Derlin
- Protein OS-9 homolog
- Cell division control protein Cdc48
- Ubiquitin-conjugating enzyme E2 2
- AAA family ATPase, putative
- RING-type E3 ubiquitin transferase
- UV excision repair protein RAD23
- Protein png1
- UBX domain protein, putative
Sequence:
MRLAAYAGASAALATAIVLKALHQRANFYAACVYLSQSSANLMILTNLCLLVVGFFLFWLQRLLYGPLRPIETEQLYEKAWFAVTETCLAMTIFRGELGGWFLVMFVCLLVGKVWGWIGEGRVEFLEQQPPANPRLFHTRLAISLVLAVLYDSFMLKYCITTVLEQARPDMMVMFGFEFAILTILSSSTAARYTISLVELYITRQQIKAKVEERRREIRAAREEALRQNAQTGETPPAADLPDENDIDQMEIDVPGWEEKGRWIFYLDLLTDFFKLTVYLSFFAILFMFYGLPIHILRDVVVTIRSFVRRITDFVRYRNATRDMNERYPDATPEEVAREDVCIICREEMAHWQEPAGVGEGGAAPAQPRPRIPERLRPKKLPCGHILHFSCLRSWLERQQNCPTCRRPVMAPTRGRDHPPANINLVQGNGGAGPQPNVPAGNQPFGQNGPADNLPRARIFQFGPFRIGFGAGRGDLFRNFHQQIHQGNAPAQQANNGIPPGARQIGFGLGFGRPTPAPVPQALPTNTPSNFVQMQNQLHQMELQIMQEINNLRVTAEQLHYVRLLQAELQRLRNPPAASSDPNTTITPASTFQPSSSLSATLRRQFTSDPQASAIPSGDSRLPEGLSLPEGWSLIPLQSAGQGPSGISSPVPTTAPEPIPTVQVREGPSVTENSAPAAGMNGESSSTVDAARSPTSSLPDWGSETPTAAAHSYIESSPQNLDKELFGKPSETKESSAWDDEATNTDKSPESSSSKGKARVVTVEDAADEET
Protein: Ixosin-B (A7UDM9)
Organism: Ixodes sinensis (Hard tick)
Function: Has antifungal activity against C.albicans. Has antibacterial activity against the Gram-positive bacterium S.aureus and the Gram-negative bacterium E.coli. Lacks hemolytic activity against rabbit erythrocytes.
Interaction partners:
Sequence:
MASGWTHRLLLLAAVVTLGATPIAAASMEYLVTAPGYLTPNADIKITAVVTNPSSAGQLKVDLWGTRSGIQPEQHSSGKSDVRRWRSRY
Protein: Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1) (Q00286)
Organism: Mus musculus (Mouse)
Function: Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P28069}.
Interaction partners:
- Homeobox protein prophet of Pit-1
- Homeobox expressed in ES cells 1
- Thyrotropin subunit beta
- LIM/homeobox protein Lhx4
- Growth hormone-releasing hormone receptor
- LIM/homeobox protein Lhx3
- Prolactin
- Pituitary homeobox 1
- T-box transcription factor TBX19
- Prolactin-5A1
Sequence:
MSCQSFTSADTFITLNSDASAALPLRMHHSAAECLPASNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPLHQPLLAEDPAASEFKQELRRKSKLVEEPIDMDSPEIRELEQFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISVAAKDALERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
Protein: Large ribosomal subunit protein mL45 (39S ribosomal protein L45, mitochondrial) (A0A087X2D5)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MAAPIPQGFSCLSRFLGWWSRQPVLVTQSAAIVPVRTKKRFTPPIYQPKFKTEKEFMQHARKAGLVIPPEKSDRSIHLACTAGIFDAYVPPEGDARISSLSKEGLIERTERMKKTMASQVSIRRIKDYDANFKIKDFPEKAKDIFIEAHLCLNNSDHDRLHTLVTEHCFPDMTWDIKYKTVRWSFVESLEPSHVVQVRCSSMMNQGNVYGQITVRMHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFEKQLTNPYGSWRMHTKIVPPWAPPKQPILKTVMIPGPQLKPEEEYEEAQGEAQKPQLA
Protein: RNA-dependent RNA polymerase (EC 2.7.7.48) (Q9Y7G6)
Organism: Neurospora crassa
Interaction partners:
Sequence:
MNPITPRKRNSPVEEIINRLNNDYNLGLQCVADTTLTPHRRKELAESDEDFGRHDKIYRALNFLYWRKDDSLNQAEANFFIEAKAASSNWVPKAHADPDTLPWSKEPPRAATAGQQWALQTVLLEVLNRFMPPPNNTPGRTFGRTLSGPSGLSRPTSTNTKRKDEPANVTFADPPKRSLTRSATGPPIHGAAIPLKFPDPVNTGSKRPSLESENLNQCTKRAKGKLSDNVAAAAAPPVPIASALDKVPTRRHANTRDPTATGHRRADQVDSFDTSQGTSYGSSVFSACRHNQSTTQSSFEAPPSQPREKRPVDATVFEAGHLIESPSKGRTTKSHIDNQPLSSSSQGETSFSTYYESFPSSGGEGAIPEPSRSNGLARSEESARSQVQVHAPVVAARLRNIWPKFPKWLHEAPLAVAWEVTRLFMHCKVDLEDESLGLKYDPSWSTARDVTDIWKTLYRLDAFRGKPFPEKPPNDVFVTAMTGNFESKGSAVVLSAVLDYNPDNSPTAPLYLVKLKPLMFEQGCRLTRRFGPDRFFEILIPSPTSTSPSVPPVVSKQPGAVEEVIQWLTMGQHSLVGRQWRAFFAKDAGYRKPLREFQLRAEDPKPIIKERVHFFAETGITFRPDVFKTRSVVPAEEPVEQRTEFKVSQMLDWLLQLDNNTWQPHLKLFSRIQLGLSKTYAIMTLEPHQIRHHKTDLLSPSGTGEVMNDGVGRMSRSVAKRIRDVLGLGDVPSAVQGRFGSAKGMWVIDVDDTGDEDWIETYPSQRKWECDFVDKHQRTLEVRSVASELKSAGLNLQLLPVLEDRARDKVKMRQAIGDRLINDLQRQFSEQKHALNRPVEFRQWVYESYSSRATRVSHGRVPFLAGLPDSQEETLNFLMNSGFDPKKQKYLQDIAWDLQKRKCDTLKSKLNIRVGRSAYIYMIADFWGVLEENEVHVGFSSKFRDEEESFTLLSDCDVLVARSPAHFPSDIQRVRAVFKPELHSLKDVIIFSTKGDVPLAKKLSGGDYDGDMAWVCWDPEIVDGFVNAEMPLEPDLSRYLKKDKTTFKQLMASHGTGSAAKEQTTYDMIQKSFHFALQPNFLGMCTNYKERLCYINNSVSNKPAIILSSLVGNLVDQSKQGIVFNEASWAQLRRELLGGALSLPDPMYKSDSWLGRGEPTHIIDYLKFSIARPAIDKELEAFHNAMKAAKDTEDGAHFWDPDLASYYTFFKEISDKSRSSALLFTTLKNRIGEVEKEYGRLVKNKEMRDSKDPYPVRVNQVYEKWCAITPEAMDKSGANYDSKVIRLLELSFLADREMNTWALLRASTAFKLYYHKSPKFVWQMAGRQLAYIKAQMTSRPGEGAPALMTAFMYAGLMPDKKFTKQYVARLEGDGSEYPDPEVYEVLGDDDFDGIGFTGNGDY