wanglab/gogpt-training-data huggingface dataset:
Protein: Superkiller complex protein 3 (Ski3) (Tetratricopeptide repeat protein 37) (TPR repeat protein 37) (Tricho-hepatic-enteric syndrome protein) (Thespin) (Q6PGP7)
Organism: Homo sapiens (Human)
Function: Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16024656}. Nucleus {ECO:0000269|PubMed:16024656}.
Interaction partners:
- Superkiller complex protein 2
- Superkiller complex protein 8
- HBS1-like protein
- Exosome RNA helicase MTR4
- Exosome complex component CSL4
- Exosome complex component RRP41
- Exosome complex component RRP45
- Small ribosomal subunit protein RACK1
- Ubiquitin-like protein FUBI
- 5'-3' exoribonuclease 1
Sequence:
MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLYYQEKKHLEVARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNNETQQLLFTAFENALGLSDKIPSEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPLEVLCLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLKESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSIVESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATLSKAALNELLKHIKHKDSNYQRCLLTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLLSRVVAQYAQRNAKGGVVAGNVAHILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQKAALLSPGDPAIWAGLMAACHADDKLALVNNTQPKRIDLYLALLSAVSASIKDEKFFENYNQSLEKWSLSQAVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKPLPDAVLEELQKTVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKLSSLLRLALLALKVCMANISNDHWPSLVQEATTEALKLCFCPLAVLLQALLQFKRKMGARETRRLLERVVYQPGYPKSIASTARWYLLRHLYAKDDYELIDVLVNNAKTHGDTRALELNQRLSSQ
Protein: Transcription initiation factor TFIID subunit (A0A8I6A7N8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR003047}.
Interaction partners:
Sequence:
MLSLFQECKKHLAGLGALGLGSLITELTANEELSGTDGTLVNDEGWIRSREDAVDYSDINEVAEDESRRYQQTMGSLQPLCHTDYDEDDYDADCEDIDCKLMPPPPPPPGPVKKERDQDGITGVSEDGEGIILPSIIAPSSLASEKVDFSSSSDSESEMGPQEATQSESKDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEEECSVELEVNQKSLWNYDYAPPPLPEQCLSDDEITMMAPVESKFSQSTGDTDKVMDTKPRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKMKKTEHDSTMKYNIMKKLRKLEENNGVDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFTATLDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQNMPRILEPPVLTLDPNDENLILEIPDEKEEATSNSPSKENKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPESDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAAGGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKAAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCHQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDNSTSLSVSRDASVYQDESNLSVLDIPSATSEKQLTQEGGDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVESGSIRPKQPRMLQENTRMGMENEESMMSYEGDGGEASRGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEQRSGPSVLSQVQLSEDEEDSEDLHSIAGDSDLDSDE
Protein: Coatomer subunit zeta (Q9IB48)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU366053}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU366053}; Peripheral membrane protein {ECO:0000256|RuleBase:RU366053}; Cytoplasmic side {ECO:0000256|RuleBase:RU366053}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000256|RuleBase:RU366053}; Peripheral membrane protein {ECO:0000256|RuleBase:RU366053}; Cytoplasmic side {ECO:0000256|RuleBase:RU366053}.
Interaction partners:
Sequence:
MDTLILEPSLYTVKAVLIMDNDGERLYAKYYDDTYPTVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSNIDLYFYVIGSSHENELMLMSVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGDDVPLTEQTVTQVLQSAKEQIKWSLLR
Protein: Cathepsin 8 (EC 3.4.22.-) (Cathepsin 2) (Q9JI81)
Organism: Mus musculus (Mouse)
Function: Probable protease (By similarity). In placenta, plays a role in promoting giant cell differentiation. Also plays a role in placental spiral artery remodeling by direct degradation of smooth muscle alpha-actin.
Subcellular location: Secreted {ECO:0000269|PubMed:18776147}. Lysosome {ECO:0000269|PubMed:18776147}. Endosome {ECO:0000269|PubMed:18776147}. Note=Localizes to the cytoplasm with a punctate staining pattern indicative of a predominant lysosomal and endosomal localization. {ECO:0000269|PubMed:18776147}.
Interaction partners:
Sequence:
MGPAVLLAILCLGVAEVTQSSDPSLDSEWQEWKRKFNKNYSMEEEGQKRAVWEENMKLVKQHNIEYDQGKKNFTMDVNAFGDMTGEEYRKMLTDIPVPNFRKKKSIHQPIAGYLPKFVDWRKRGCVTPVKNQGTCNSCWAFSAAGAIEGQMFRKTGKLVPLSTQNLVDCSRLEGNFGCFKGSTFLALKYVWKNRGLEAESTYPYKGTDGHCRYHPERSAARITSFSFVSNSEKDLMRAVATIGPISVGIDARHKSFRLYREGIYYEPKCSSNIINHSVLVVGYGYEGKESDGNKYWLIKNSHGEQWGMNGYMKLARGRNNHCGIASYAVYPRV
Protein: Bifunctional purine biosynthesis protein ADE16 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)] (P54113)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR). Also catalyzes the cyclization of FAICAR to IMP.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:10877846}.
Interaction partners:
- Adenylosuccinate lyase
- Bifunctional purine biosynthesis protein ADE17
- Phosphoribosylglycinamide formyltransferase
- Adenylosuccinate synthetase
- Serine hydroxymethyltransferase, cytosolic
- Bifunctional purine biosynthetic protein ADE5,7
- Serine hydroxymethyltransferase, mitochondrial
- Amidophosphoribosyltransferase
- C-1-tetrahydrofolate synthase, cytoplasmic
- Inosine-5'-monophosphate dehydrogenase 3
Sequence:
MGKYTKTAILSVYDKTGLLDLAKGLVENNVRILASGGTANMVREAGFPVDDVSSITHAPEMLGGRVKTLHPAVHAGILARNLEGDEKDLKEQHIDKVDFVVCNLYPFKETVAKIGVTVQEAVEEIDIGGVTLLRAAAKNHSRVTILSDPNDYSIFLQDLSKDGEISQDLRNRFALKAFEHTADYDAAISDFFRKQYSEGKAQLPLRYGCNPHQRPAQAYITQQEELPFKVLCGTPGYINLLDALNSWPLVKELSASLNLPAAASFKHVSPAGAAVGLPLSDVERQVYFVNDMEDLSPLACAYARARGADRMSSFGDFIALSNIVDVATAKIISKEVSDGVIAPGYEPEALNILSKKKNGKYCILQIDPNYVPGQMESREVFGVTLQQKRNDAIINQSTFKEIVSKNKALTEQAVIDLTVATLVLKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKTDNWWLRQHPKVLNMKWAKGIKRADKSNAIDLFVTGQRIEGPEKVDYESKFEEVPEPFTKEERLEWLSKLNNVSLSSDAFFPFPDNVYRAVQSGVKFITAPSGSVMDKVVFQAADSFDIVYVENPIRLFHH
Protein: Auxin efflux carrier component 3a (OsPIN3a) (OSPIN10a) (OsPIN3t) (Q5VP70)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Acts as a component of the auxin efflux carrier. Involved in the polar auxin transport which may regulate crown root development and response to water stress.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22882529}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Auxin efflux carrier component 2
Sequence:
MISGHDFYTVMAAVVPLYVAMFLAYGSVRWWGIFTPDQCSGINRFVAIFAVPLLSFHFISTNDPYAMNLRFLAADTLQKLLVLAGLAAWSRLPSRTGAPRLDWSITLFSLSTLPNTLVMGIPLLIAMYGPYSGSLMVQIVVLQCIIWYTLMLFLFEFRAARMLIADQFPDTAASIVSLHVDPDVVSLEGGHAETEAEVAADGRLHVTVRRSSVSRRSLLVTPRPSNLTGAEIYSLSSSRNPTPRGSNFNHADFFAMVGGGPPPPTPAAVRGSSFGASELYSLQSSRGPTPRQSNFDEHSARPPKPPATTTGALNHDAKELHMFVWSSSASPVSEVSGLPVFSGGGGGGALDVGAKEIHMVIPADLPQNNGSGKEHEEYGAVALGGGGGGENFSFGGGKTVDGAEAVDEEAALPDGLTKMGSSSTAELHPKVVDVDGPNAGGGAAGAGQYQMPPASVMTRLILIMVWRKLIRNPNTYSSLLGLAWSLVAFRWHVSMPAIVEKSISILSDAGLGMAMFSLGLFMALQPSIIACGKSAAVVSMAVRFLAGPAVMAAASIAIGLRGTLLHVAIVQAALPQGIVPFVFAKEYNVHPAILSTAVIFGMLIALPITLLYYILLGL
Protein: Erythrocyte binding protein (Q9N9G9)
Organism: Plasmodium reichenowi
Interaction partners:
Sequence:
SFFVLYFAKARNEYDIKENEKFLEVYKEKFNELDKKKYGNVQKTDKKIFSFIENKLDILNNSKSNKRWKSYGTPDNIDKNMSLINKYNNKETFNNNYQSFLSTSSLIKQNRYVPINAVRVSRILSFLDSKINNGRNTSSNDGDLRNCREKRKGNEWDCKKKNGTSNYVCIPDRRIQLCIVNLSIIKTYTKETMKDHFIEASRRESQLLLKKNDNNYNSKFCNDLKNSFLDYGHLAMGNDMDFGGYSTKAENKIQEVFKGVHGKISEHEIKNFRKKWWNEFREKLWEAMISEHKNNLSDCKNIPEEELQINQWIKEWHGEFLSERNNRLKLPKSKCKNNTLYEACAKECIDPCMKYRDWIIKSKFEWHTLSKEYERKNVSNKDAEKYLIKFSKNNDAKVSLLLDKCDAEYSKYCDCKHTTTLVKSVLNGKDNTSKEERETIDLDDFSKFGCDKNSVDTNRKEWECKKPYILSTKDVCVPPRRQELCLGNIDRIYDKNLLMIKEHILAIAIYESRILKRKYKNKDDNEVCNVINKSFADIRDIIKGSDYWNDLSNRKLVGKINTNSKYVHKNKENDKLFRDEWWNVIKKDVWNVMSWVFKDKTVCKEDDIENIPQFFRWFSEWGDDYCQYKLKMIDTLKVACEEKGYDDITCKNKCSSYKDWISKQKYLYDKQVTIYKEYQRNNNRIYPIVKTMEPKVYLKEYSKKCSNINFEDEFNEEVHSDYKNKCMISTKVLDVPIPAEKNVTEALETVVPKENTEIERKNESDTEEQKNQEIPNNYLKDSQQRVGENGTKVSSQEDLRGSRNEEGVTQEFGLNDEIPKGEEQISGKSGVIQNRSESEMGISTSEESRHEEGHNEQTLSTSVDQSELSDTLQSHEDTKENDELPLASSTITSPMESGSSDTEETQSISEGPKGNEQKERDDDSSSKISVSPEISRTETHDKDTSNLLRLKEDVDISMPKAVIGKDPNDHINNTAEGDHISGVNSSPLSDGVRPDKNHEEVKEHTSNPDNVQQSGENVNMNVENQLKDTLENTSSSLGEGKAHEELSEPNLSSGQDMSNTPAPLDNTSEETTERISNNEYKVNEREDERTLTKEYEDIVLKSHMNRESDDDELDGKNSDVPTVNDESEDVEEKMKRNDTSEISEDSSQHIESDQQENDMKTVGDLGTIHVQNEINDSVTGENKEQTVHGDEGVRLSHKDKHKINLEDKNSNILHLKDMRNEENERKQLANQNINISQQRDLQEHGFHTMNNLHGDGVSEGSQINHGNPVKRQDRGKPSGNVLNMGSNNNNFHNIPSRYNLYDKKLNLDLYVNRNDSTTKELIKKLAEINKCENEISAKYCSDMIDKEIPLKTCTKEKTINLCCAVADYCLSYFTYDSKEYSNCTKREFEDPSYTCFRKKGFSSMIFKFLITNKIYYYFYTYKNAKVTIKKINF
Protein: Erythritol/L-threitol-binding protein (A0QXD9)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: Part of an ABC transporter complex involved in erythritol/L-threitol import. Binds erythritol and L-threitol. Functions in the transport for the degradation pathways of erythritol and L-threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source.
Interaction partners:
- ABC transporter, permease protein
- Transporter
- Trehalose import ATP-binding protein SugC
- Trehalose import ATP-binding protein SugC
- Erythritol/L-threitol dehydrogenase
- D-erythrulose kinase
- D-erythrulose-4-phosphate isomerase 1
- Sugar ABC transporter permease protein
Sequence:
MMSRESQPGLHRQLSRRNMLAAMGLAGAAAVSLPVLSACGVGGRTNAPNGASEVTGGFDWRKASGSTINILQTPHPYQQSYQPLLKEFTELTGINVNVDLVPEADYFTKLNTELAGGTGKHDAFMLGAYFIWQYGPPGWIEDLNPWLQNSSATNAEYDFEDIFEGLRTSTRWDFELGNPLGTGGQWAIPWGFENNVVAYNKAYFDQRGITKLPDNFDDFIQLAIDLTDRSENRYGIATRGSKSWATIHPGFMTQYVREGAVDYTFDGTDLVAEMDSDKAVEFTRKWIEMQHKAGPTSWTTYDYPNATGDLGDGTAMMVYDADSATYPKNKPGASAQAGNLGWYPGPAGPDGNYKTNLWTWTWAMNANSRNKLPAWLFIQWATGKESMNKAVEGGIYADPVRQSVFDTTFKRIAADQHGYLETFETVIGSSKIQFTPQKKFFDTTKDWAVALQDIYGGDDAASRLRSLAKTNTSKVNL
Protein: NMDA receptor 2, isoform E (E1JJC6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}.
Interaction partners:
Sequence:
MHGISFYWHATPCRIRACAPILSTLCKEFLRVNVSAILYMMNNEQFGHSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDLMELVNSEARVMLLYATQTEAITILRAAEEMKLTGENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLEKVMDKHGIKAPQLRLASSSDLLNHHHLKERPPLLGNLSLAASAQDLYRWSYKTEIAEMETVL
Protein: Xanthosine permease (Xanthosine transporter) (P45562)
Organism: Escherichia coli (strain K12)
Function: Uptake of xanthosine. Can also transport other nucleosides such as inosine, adenosine, cytidine, uridine and thymidine. Transport is driven by a proton motive force.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:11466294, ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:7559336}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Purine nucleoside phosphorylase 2
- HTH-type transcriptional regulator XapR
- Nucleoside permease NupC
- Inner membrane ABC transporter permease protein YejE
Sequence:
MSIAMRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVNAMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSLQLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAYGDPSTTGFILLLLSMIVYGCAFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWQTIWLVFAGYALFLAVIFFFGFKYNHDPEKIKHRAVTH
Protein: VP9 (Q9YWN5)
Organism: Banna virus (BAV)
Interaction partners:
Sequence:
MLSETELRALKKLSTTTSRVVGDSTLALPSNVKLSKGEVEKIAVTKKEMFDELAQCNLPTIELITREHTFNGDVIRFAAWLFLMNGQKLMIANNVAVRMGMQYATNLAGNNVKITYVTSNNVVKLGHIAAGVLANPYSNKGSGLFITYEHNLISNQIETGKVCVLFITSLSTTASSTNSFAYSACSVPIEDWDFNMIKLTAETSCASLTAMTNLVNSLVPGERTRPVGLYVDIPGVTVTTSASSGSLPLTTIPAVTPLIFSAYTKQVEEVGVINTLYALSYLP
Protein: Cystathione gamma lyase, putative (EC 2.5.1.-) (Q38DH3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cystathionine beta-synthase, putative
- 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
- Homocysteine S-methyltransferase, putative
Sequence:
MYCYCLCILFFFFFFSFCEGKLCLIFVLLYFIESKMSKQQHLVSDFEDGSGSWSNIEQGFDTLLVHGGVKPDPVTGAVLTPIYQSTTFVQESIELYQSRGFSYTRSANPTVKALEEKLCAVEKGDYATVYSTGMAATTTVVSALMNAGDHAIVTDCSYGGTNRACRVFFTRFGMEFTFVDMRDLSNVEKAIKSNTKLVISETPANPTLTLTDIRALSKICKAKGLLHVCDNTFATAFIMRPIDLGADVSLISTTKFVDGHNMTVGGALVTKRKDLDEKLRLTQNILGNAMSPFVAFLQLQTMKTMSLRVTKQSANAQKVAEFLETHPIVDKVSYPGLKSFPQKELADRQHSNGNHGGMLWFELKGGTAAGRRLMDTVQRPWSLCENLGATESIITCPSVMTHANMTTEDRLKVGITDGFIRVSCGIEDAEDLVAALKKALDAMCH
Protein: Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein) (A2RRV9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.
Interaction partners:
- MMS19 nucleotide excision repair protein homolog
- Probable cytosolic iron-sulfur protein assembly protein ciao1
- Cytosolic iron-sulfur assembly component 2B
- Family with sequence similarity 234 member A.
- Iron-sulfur clusters transporter ABCB7, mitochondrial
- Post-GPI attachment to proteins factor 6
- Regulator of G-protein signaling 11
- Ferredoxin-2, mitochondrial
- Adrenodoxin, mitochondrial
- Amidophosphoribosyltransferase
Sequence:
MAVIFRSISGCITSAESVLITQQSHEELYRVLRHNKQVSSTEQKVVVVSVSPQSRASLAAHYGIGSSEVARKLTSFLKHLGVHHVFDTAFSRSFSLIESQREFLQRFSQREADKKALPMLASACPGWICYAEKTHGEFILPYISTTRSPQQIMGSLVKGYFASQKGVSPQMIYHVTVMPCYDKKLEASRPDFYLSEHETREVDCVITSGEVLKMLEEEKVSLRDVQPAPLDTMFSNVCGEELLGHAGSGSGGYLHHIYKHAAKQLFGVDVDELTYKTMKNKDFQEVTLEKDGQVLLKFAAVYGFRNIQNLVQKLKRGKSPYHFVEVMACPSGCLNGGGQLKPSADQSNKELLQQVEEVYRSEHPSVPEDDSQVAELYQSWLESVGEEKARQLLHTQYHAVEKTANGLSIKW
Protein: Protein RER1 (Q9CQU3)
Organism: Mus musculus (Mouse)
Function: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Surfeit locus protein 4
- Endoplasmic reticulum resident protein 44
- Guanine nucleotide-exchange factor SEC12
- Gamma-secretase subunit PEN-2
- Coatomer subunit epsilon
- Calnexin
- Transmembrane emp24 domain-containing protein 2
Sequence:
MSEGDSVGDSVHGKPSVVYRFFSRLGQIYQSWLDKSTPYTAVRWVVTLGLSFVYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTKQNEEFRPFIRRLPEFKFWHAATKGILVAMICTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRRYKGKEDVGKTFAS
Protein: Large ribosomal subunit protein eL30 (60S ribosomal protein L30) (L32) (RP73) (YL38) (P14120)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22096102}.
Interaction partners:
- Large ribosomal subunit protein eL20A
- Small ribosomal subunit protein uS8A
- Large ribosomal subunit protein uL5B
- Small ribosomal subunit protein eS7A
- Large ribosomal subunit protein eL33A
- Large ribosomal subunit protein eL31A
- Small ribosomal subunit protein uS4A
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL5A
- Large ribosomal subunit protein eL21A
Sequence:
MAPVKSQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVSILEAGDSDILTTLA
Protein: Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme atg3) (O43035)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity). Plays a role in meiosis and sporulation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Autophagy-related protein 8
- Autophagy protein 5
- Ubiquitin-like modifier-activating enzyme atg7
- Ubiquitin-like protein ATG12
- Serine/threonine-protein kinase atg1
- Putative lipase atg15
- Probable cysteine protease atg4
- Phosphatidylinositol 3-kinase pik3
- Vacuolar protein sorting-associated protein atg6
- Autophagy-related protein 18
Sequence:
MAQRLTSAFLNWREHITPASKTSDFENTGMISPEEFVLAGDYLVSKFPTWSWECGDRIRGFLPKDKQYLVTRHVFCVQRNINIGVNEEWVDIETDDTRNKDDDQDDDAISSIHSDTSDIASAERLKGQSKELSDSGPLPLKDEEDDDQMVSPVIKEDEGRYYDLYIVYDKYYRTPRLFLRGWNAGGQLLTMKDIYEDVSGEHAGKTVTMEPFPHYHSHNTMASVHPCKHASVLLKLIKQHRERNDPIRVDQYMVLFLKFVSTMLPYFEIDYTIQA
Protein: Anthranilate phosphoribosyltransferase (EC 2.4.2.18) (P9WFX5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
Interaction partners:
- Anthranilate synthase component 2
- Anthranilate synthase component 1
- Indole-3-glycerol phosphate synthase
- Tryptophan synthase alpha chain
- Tryptophan synthase beta chain
- Salicylate synthase
- Probable para-aminobenzoate synthase component I PABD
- Phosphoribosyl isomerase A
- Probable cytochrome c oxidase subunit 3
- Pyrroline-5-carboxylate reductase
Sequence:
MALSAEGSSGGSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
Protein: ER-derived vesicles protein ERV46 (P39727)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. The C-terminal Phe-Tyr motif is required for exit from the endoplasmic reticulum. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Recycles between endoplasmic reticulum and Golgi. Resides in the endoplasmic and Golgi compartments, and then packaged into endoplasmic reticulum derived vesicles.
Interaction partners:
- ER-derived vesicles protein ERV41
- Vacuolar protein sorting-associated protein 45
- tRNA modification GTPase MSS1
- Endoplasmic reticulum vesicle protein 25
- Protein EMP47
- Signal peptidase complex subunit 1
- Small COPII coat GTPase SAR1
- Endoplasmic oxidoreductin-1
- Protein transport protein SEC13
- Protein RER1
Sequence:
MKRSTLLSLDAFAKTEEDVRVRTRAGGLITLSCILTTLFLLVNEWGQFNSVVTRPQLVVDRDRHAKLELNMDVTFPSMPCDLVNLDIMDDSGEMQLDILDAGFTMSRLNSEGRPVGDATELHVGGNGDGTAPVNNDPNYCGPCYGAKDQSQNENLAQEEKVCCQDCDAVRSAYLEAGWAFFDGKNIEQCEREGYVSKINEHLNEGCRIKGSAQINRIQGNLHFAPGKPYQNAYGHFHDTSLYDKTSNLNFNHIINHLSFGKPIQSHSKLLGNDKRHGGAVVATSPLDGRQVFPDRNTHFHQFSYFAKIVPTRYEYLDNVVIETAQFSATFHSRPLAGGRDKDHPNTLHVRGGIPGMFVFFEMSPLKVINKEQHGQTWSGFILNCITSIGGVLAVGTVMDKLFYKAQRSIWGKKSQ
Protein: Flagella synthesis protein FlgN (P0A1J7)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Required for the efficient initiation of filament assembly.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Negative regulator of flagellin synthesis
- Flagellar hook-associated protein 3
- Flagellar hook-associated protein 1
- Flagellar secretion chaperone FliS
- Flagellar FliJ protein
- Flagella basal body P-ring formation protein FlgA
- Flagellar hook-associated protein 2
- Flagellum-specific ATP synthase
- Basal-body rod modification protein FlgD
- Flagellar hook protein FlgE
Sequence:
MTRLSEILDQMTTVLNDLKTVMDAEQQQLSVGQINGSQLQRITEEKSSLLATLDYLEQQRRLEQNAQRSANDDIAERWQAITEKTQHLRDLNQHNGWLLEGQIERNQQALEVLKPHQEPTLYGADGQTSVSHRGGKKISI