wanglab/gogpt-training-data huggingface dataset:
Protein: NADPH oxidase 2 (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b-245 heavy chain) (Heme-binding membrane glycoprotein gp91phox) (Neutrophil cytochrome b 91 kDa polypeptide) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome) (Q9ERL1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Neutrophil cytosolic factor 1
- small monomeric GTPase
- Cytochrome b-245 light chain
- NADPH oxidase 4
- NADPH oxidase 1
- Neutrophil cytosol factor 4
- NADPH oxidase 3
- Dual oxidase 1
- Ras-related C3 botulinum toxin substrate 1
- Vascular cell adhesion protein 1
Sequence:
MGNWAVNEGLSIFVILVWLGLNVFLFVKYYKVYDDEPKYNYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRIRRQLDRNLTFHKMVAWMIALHTAIHTIAHLFNVEWCVNARVGTSDPYSVALSNIGDKENEEYLNFAREKIKNPEGGLYVAVTRLAGITGIVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTSDSLKEHNLDVCADKIKEWGKIKECPVPKFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPQVSKLEWHPFTLTSAPEEDFFSIHIRIVGDWTEGLFNACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCDNATSLRLKKIYFYWLCRDTHAFEWFADLLQLLETQMQERNNANFLSYNIYLTGWDESQANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQHPNTRIGVFLCGPEALAKTLSKQSISNSESGPRGVHFIFNKENF
Protein: Synaptic vesicle glycoprotein 2C (Q496J9)
Organism: Homo sapiens (Human)
Function: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q9Z2I6}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Z2I6}. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas. {ECO:0000250|UniProtKB:Q9Z2I6}.
Interaction partners:
- Synaptic vesicle glycoprotein 2B
- Pancreatic secretory granule membrane major glycoprotein GP2
- Synaptic vesicle glycoprotein 2A
- Laminin subunit gamma-2
- Synaptotagmin-1
- Laminin subunit gamma-3
- Laminin subunit gamma-1
Sequence:
MEDSYKDRTSLMKGAKDIAREVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEDDDDYYPAGETYNGEANDDEGSSEATEGHDEDDEIYEGEYQGIPSMNQAKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRDNTIKLTIVWFTLSFGYYGLSVWFPDVIKPLQSDEYALLTRNVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFFHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKSIPILLASTVLVCGGLVGLCLPDTRTQVLM
Protein: Zinc finger CCCH domain-containing protein 59 (AtC3H59) (Zinc finger CCCH domain and WD40 repeat-containing protein 3) (Q9FKR9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- PPPDE putative thiol peptidase family protein
- Zinc finger CCCH domain-containing protein 12
- Zinc finger CCCH domain-containing protein 14
- Zinc finger CCCH domain-containing protein 15
- Zinc finger CCCH domain-containing protein 46
- Zinc finger CCCH domain-containing protein 17
- RING-box protein 1a
- RING-box protein 1b
- Zinc finger CCCH domain-containing protein 28
- Zinc finger CCCH domain-containing protein 51
Sequence:
MGHQSSWMKQTVIDSVVQSSKVGVFSMFSMDYKAPRKYSHGRNFGVARQQDFAADIVTRRPYAPYDNGMKKGPNKLSRNLVWTSKEYKSPEGNRPRQNAANGSAKPQVIGTGHRVSNQPRKNAVYGPRSSSLSDTRGCGPRLNGSPKKSVCNFWKDGNCKKGEKCQFLHSWSCFPGLAMVAALEGHKNDIKGIALPQGSDKLFSVSGDGTLLIWDCNSGQCVRSINLQAEAGSLISEGPWVFLGLPNAVKAFNVQNSKDVHLEGVVGQVHAMTAANGMLFAGTSSGSILVWKATDSESDPFKYLTSLEGHHSGEVTCFVVGGEVLYSGSVDKTIKVWDLNTLQCRMTLKQHIGTVTSLLCWDKCLISSSLDGTIKLWACSENESLKVVQTRKQELSVHTLCGMHDAEAKPIMFCSYQNGAVGIFDLPSFEERGKMFSTQTICTLTIGPGGLLFSGDKSGNLRVWSLASGTKV
Protein: Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) (O18276)
Organism: Caenorhabditis elegans
Function: GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel.
Subcellular location: Postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Ligand-Gated ion Channel
- Ligand-Gated ion Channel
- Neurotransmitter-gated ion-channel ligand-binding domain-containing protein
- Acetylcholine receptor-like protein cup-4
- Gamma-aminobutyric acid type B receptor subunit 1
Sequence:
MRRSKTRRIFHVSITLLLVSTIFCQNGTKPHNNSTSDQMSSSWSNRSQTMYSNASSLLSDLLLDYDIRLRPGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTDERLRWSNEIPIDEMTLSGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAYGMRLTSTLSCSMNLRNFPLDSQNCTVEIESYGYTTSEVLMKWNYPLAVHGVEQADVPQFTITGFHTEDSIVSTATGSYQRLSLVFQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRQSLPRISYVKSIDIYLVMCFVFVFAALLEYAAVNYSYWGRERGKGGGGNEWPVNGANKEDRESAVNVQKWVPSGLMDGVPQPQDRRVEALEEAMSTSNTAAQNNNFESTSKPKKRSSSPIPPLCRAGNTISEESESPDYPRYSTTSLKGARPHASLNHKTHHLKGRSSARAKRRMTLARMNVSMKQSISGIGRRARKVIPTIRVRDVNLIDKYSRVVFPVCFIVFNLFYWSYYMMVPS
Protein: V-type proton ATPase subunit a (F6ZFB8)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
VSAVAHRIPCQDMPPTLIRTNRFTSSFQGIVDAYGVGRYREVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAMVLTENRPAVKAAQNE
Protein: Cyclin N-terminal domain-containing protein (Q9BL45)
Organism: Caenorhabditis elegans
Interaction partners:
- MutS protein homolog 5
- Zip homologous protein 3
- Meiotic recombination protein spo-11
- HORMA domain-containing protein
- Double-Strand Break factor
- MutS protein homolog him-14
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- DNA repair protein RAD51 homolog
- HORMA domain-containing protein
- Synaptonemal complex protein 3
Sequence:
MSSSRSHRKNTSTLGTPAVSAANQTVKNPNLKKNEPKSDNEPPKTLVSMEPDFYDPRGACHMIYWTDCIAQMAVDIRERQNAANQSDFDFMKPKLVEYVFTVCVRLRLPNEVRFTAALILNSFMLRHLCSLHDFMERQEMSIQRKKREWENLESNMERQIPLRILTAIQISSKFHSYHDSLSSRQVVNTLRKIGLPYTISAVLESEQRVFKLIGFKMPDSPLDACEMALKVLTFTMKKRGMIDEEKYNDLWQHTLIVLDVCFINHIELYERFIRKCPAICRTEERLNISKFKWDIQLLAAATVQTAYILLLGTSQIANVSVIINNLLRCDNAYVEPLKQSIIELACAKKNESIPECSTSS
Protein: Transcription factor HHO5 (MYB-domain transcription factor HHO5) (Protein HRS1 HOMOLOG 5) (Protein ULT1 INTERACTING FACTOR 1) (F4JRB0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional repressor that functions with ULT1 in a pathway which regulates floral meristem homeostasis and organ number in the flower. Binds specifically to the DNA sequence motif 5'-GTAGATTCCT-3' of WUS promoter, and may be involved in direct regulation of WUS expression. Binds specifically to the DNA sequence motif 5'-AAGAATCTTT-3' found in the promoters of AG and the NAC domain genes CUC1, CUC2 and CUC3, and may be involved in direct regulation of these gene expressions.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:26903506}. Cytoplasm, cytosol {ECO:0000269|PubMed:26903506}. Note=Localizes in cytosolic foci. {ECO:0000269|PubMed:26903506}.
Interaction partners:
- Protein ULTRAPETALA 1
- Berberine bridge enzyme-like 17
- Putative defensin-like protein 244
- Homeodomain-like superfamily protein
- Duplicated homeodomain-like superfamily protein
- Polynucleotide 5'-hydroxyl-kinase NOL9
- Protein ULTRAPETALA 2
- At1g49010
- ELM2 domain-containing protein
Sequence:
MVQTETDQRMGLNLNLSIYSLPKPLSQFLDEVSRIKDNHSKLSEIDGYVGKLEEERNKIDVFKRELPLCMLLLNEEIVFLCVAIGALKDEARKGLSLMASNGKFDDVERAKPETDKKSWMSSAQLWISNPNSQFRSTNEEEEDRCVSQNPFQTCNYPNQGGVFMPFNRPPPPPPPAPLSLMTPTSEMMMDYSRIEQSHHHHQFNKPSSQSHHIQKKEQRRRWSQELHRKFVDALHRLGGPQVATPKQIRDLMKVDGLTNDEVKSHLQKYRMHIRKHPLHPTKTLSSSDQPGVLERESQSLISLSRSDSPQSPLVARGLFSSNVGHSSEEDEEEEDEEEEKSDGRSSCRNDETKKKRQVLDLEL
Protein: Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain) (Q07009)
Organism: Rattus norvegicus (Rat)
Function: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon Ca(2+) binding. {ECO:0000250}.
Interaction partners:
- Calpain small subunit 1
- Calpastatin
- Calpain-1 catalytic subunit
- Talin 1
- Talin 2
- BH3-interacting domain death agonist
- Interleukin-1 alpha
- BCL2-antagonist/killer 1, isoform CRA_b.
- Apoptosis regulator BAX
- Cyclin-dependent kinase 5 activator 1
Sequence:
MAGIAMKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL
Protein: GRB2-related adapter protein-like (Q8TC17)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLGPKSHSRLG
Protein: Acta1a protein (Actin alpha 1, skeletal muscle a) (Actin, alpha 1a, skeletal muscle) (Q567E8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MCDDDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMGSAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEIAALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
Protein: Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (P9WJJ7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the catabolism of quinolinic acid (QA).
Interaction partners:
- L-aspartate oxidase
- Quinolinate synthase
- Nicotinate phosphoribosyltransferase pncB1
- Possible transcriptional regulatory protein NadR
- Probable nicotinate-nucleotide adenylyltransferase
- CinA-like protein
- Nicotinate phosphoribosyltransferase pncB2
- NAD-capped RNA hydrolase NudC
- Conserved protein
- Glutamine-dependent NAD
Sequence:
MGLSDWELAAARAAIARGLDEDLRYGPDVTTLATVPASATTTASLVTREAGVVAGLDVALLTLNEVLGTNGYRVLDRVEDGARVPPGEALMTLEAQTRGLLTAERTMLNLVGHLSGIATATAAWVDAVRGTKAKIRDTRKTLPGLRALQKYAVRTGGGVNHRLGLGDAALIKDNHVAAAGSVVDALRAVRNAAPDLPCEVEVDSLEQLDAVLPEKPELILLDNFAVWQTQTAVQRRDSRAPTVMLESSGGLSLQTAATYAETGVDYLAVGALTHSVRVLDIGLDM
Protein: Kinase suppressor of Ras A (EC 2.7.11.1) (G5EFD2)
Organism: Caenorhabditis elegans
Function: Serine/threonine-protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. Involved in sex myoblast migration. Plays a role in responses to M.nematophilum-mediated bacterial infection by promoting tail swelling and preventing constipation. Functions redundantly with ksr-2 in the Ras-mediated regulation of larval survival, the development of excretory canal and in mpk-1 phosphorylation in somatic cells. In addition, involved in determining vulval precursor cell fate during vulval induction independently of its kinase activity. Plays a role in egg-laying.
Interaction partners:
- Dual specificity mitogen-activated protein kinase kinase mek-2
- Ras protein let-60
- mitogen-activated protein kinase kinase
- Raf homolog serine/threonine-protein kinase
- Connector enhancer of kinase suppressor of ras
- Mitogen-activated protein kinase mpk-1
- Leucine-rich repeat protein soc-2
- 14-3-3-like protein 1
- Nucleoside diphosphate kinase
- 14-3-3-like protein 2
Sequence:
MMQTQVASRAGYSNLPQFGAGIAQDIKTQAINNLKECLKLTTINRFLTSSYEEDAKSVERKIFSAVYQMTKIGLIDREKREINAIWFTFVGLSAQNIRHLEICSITDFNALFSITNQELRSLADRGRLDVETKRKLLQSTVILQNHWNAYHSRTSSGSTDEPSGQSTPAIVTPSPKFNVPSLSVTSAKMIQSSSMGFATTPKSPKTSSRLVHAIPHKWHRSTKFRFSGDAVCHFCQRPLGFGFLNAWEKCRSCKWKVHTQCKGRVGDSCGLTPDHLRFLFDKLIQENNGGMWKDPQSVPGSRSMNEPAFQFPDTAIDSSSSTNSSAPSTPALPAGISGNVSSLTAPYRSERKFLFPDTENYSVHNRLPILVISEGDHPTTTEIQQETENHNKSAAASMSGNIESEGTIVANHEDSTGSQEVDSEAAPSQEAVDKFNKRADGGFTWERHAWNMSTIRGPNAQASWNEVTIQFETIEFDKQAPIIGRGRFGKVLRGFHYGDVAVKVYTMEHISDASKKAEEFKLEVSAYKNTRHDNIALFLGYFMSDGQYGMVMSLSKGSQSLYTLLHVVREKLDLATTRKIAQQICQAVSYLHTKKILHKDLRSKNILLESKNKVVITDFGILSMKRLAHPKQKSGYLTSKFWTNYIAPELAMAMRTEYDEYECDDFPFSENSDVYAFGCVWFEMLTGALPYAGELPHQILFAKTQGIRPVLPNVKCTQELKELLVSCWNTAPQDRPTLTDINLKLTALPKKPRVNRSPSFPVMMKSYESTF
Protein: Small ribosomal subunit protein mS45 (37S ribosomal protein S35, mitochondrial) (P53292)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16823961}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein mS23
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein uS4m
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein bS1m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS8m
- Small ribosomal subunit protein bS18m
Sequence:
MSYGLTGTSSKLRGTSSIFSWTQVRHFSRRRIAYPFYPFKKLGRQHPKKHDTNLKTAMRQFLGPKNYKGEYVMNKYFTVPTNHVPNYIKPDLERGQSLEHPVTKKPLQLRYDGTLGPPPVENKRLQNIFKDRLLQPFPSNPHCKTNYVLSPQLKQSIFEEITVEGLSAQQVSQKYGLKIPRVEAIVKLVSVENSWNRRNRVSSDLKTMDETLYRMFPVFDSDASFKRENLSEIPVPQKTLASRFLTIAESEPFGPVDAAHVLELEPAVETLRNLSTVGEHSSGHQQSTNKNTKVIYGELVEGERSQYKFTNAKVGKVGYRYGSGNRDNKKDRRIGFNKLGQMVYI
Protein: Zinc finger protein, conserved (Q584Z4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Eukaryotic translation initiation factor 6
- 60S ribosomal export protein NMD3
- Ribosome assembly factor mrt4
- Aminopeptidase, putative
- Guanine nucleotide-binding protein-like 1
- GTP-binding protein, putative
- Ribosome biogenesis protein NSA2 homolog
- Protein MAK16 homolog
- 60S ribosomal protein L24, putative
- 60S ribosomal protein L29
Sequence:
MSLPAPQCGACGVAFDSIEASRKHYQSDFHVHNVRMRVEGKRPVTAQEYKHMRIAEGIDVDNDGGPSFACKLCKKTFHCVQTLQAHVRSTAHLIKKEQRILARDSDAASALTSTSLGSAAVGLHRRHNAKRPKALSEGTKKTKEVKVQPEEREEDVSEVRCFACGALSDNVEANLEHLFNVHEFTIPLQEKCTDVAGLLSYVARKTNGLLCLVCGEKTRSFASLEALRAHMREKNHDRIILGPEYDEFYSISLADVDVGERLDLNNMELVVSDSRRCVQRREAEVPRPRKKDSNARIEQHRLLIAAQYETQVALRREEREEMREVHREAHKLLKRQDAHYQEHMMKVSLRSNKLHPKGYDGEGRVN
Protein: Ferric uptake regulation protein (Q5F5Y9)
Organism: Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU364037}.
Interaction partners:
- SsrA-binding protein
- Leucyl/phenylalanyl-tRNA--protein transferase
Sequence:
MEKFSNIAQLKDSGLKVTGPRLKILDLFEKHAEEHLSAEDVYRILLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDHIVCVKCGEVTEFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR
Protein: Beta-mannosidase A (EC 3.2.1.25) (Mannanase A) (Mannase A) (Q9UUZ3)
Organism: Aspergillus niger
Function: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length. Involved in the degradation of polymeric mannan and galactomannan. Releases the terminal mannose residue from mannobiose and mannotriose, as well as from galactosyl-mannobiose (GM2), galactosyl-mannotriose (GM3) and di-galactosyl-mannopentaose (G2M5).
Subcellular location: Secreted {ECO:0000269|PubMed:10553664}.
Interaction partners:
Sequence:
MRHSIGLAAALLAPTLPVALGQHIRDLSSEKWTLSSRALNRTVPAQFPSQVHLDLLRAGVIGEYHGLNDFNLRWIAAANWTYTSQPIKGLLDNYGSTWLVFDGLDTFATISILWTANRIHGQSVSPVSGSMYLPALEACQRRILIRKVSFRGGVTAEVNTCYLHIEWPDDVQLTYEYPNRWFMRKEQSDFGWDWGPAFAPAGPWKPAYIVQLDKKESVYVLNTDLDIYRKNQINYLPPDQSQPWVVNASIDILGPLPAKPTMSIEVRDTHSGTILTSRTLNNVSVAGNAITGVTVLDGLNPKLWWPQSSVIRTSTMFLSLSKVEGTRPWPVWTNGRASAPFFLNQRNITEVQRAQGIAPGANWHFEVNGHEFYAKGSNLIPPDSFWTRVTEERISRLFDAVVVGNQNMLRVWSSGAYLHDYIYDLADEKGILLWSEFEFSDALYPSDDAFLENVAAEIVYNVRRVNHHPSLALWAGGNEIESLMLPRVKDAAPSSYSYYVGEYEKMYISLFLPLVYENTRSISYSPSSTTEGYLYIDLSAPVPMAERYDNTTSGSYYGDTDHYDYDTSVAFDYGSYPVGRFANEFGFHSMPSLQTWQQAVDTEDLYFNSSVVMLRNHHDPAGGLMTDNYANSATGMGEMTMGVISYYPIPSKSDHISNFSAWCHATQLFQADMYKSQIQFYRRGSGMPERQLGSLYWQLEDIWQAPSWAGIEYGGRWKVLHHVMRDIYQPVIVSPFWNYTTGSLDVYVTSDLWSPAAGTVDLTWLDLSGRPIAGNAGTPKSVPFTVGGLNSTRIYGTNVSSLGLPDTKDAVLILSLSAHGRLPNSDRTTNLTHENYATLSWPKDLKIVDPGLKLGYSSKKTTVTVEATSGVSLYTWLDYPEGVVGYFEENAFVLAPGEKKEIGFTVLDDTTNGAWVRNITVQSLWDQKVRG
Protein: Caspase 4 (E9PMT1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFD
Protein: Motile sperm domain-containing protein 1 (Q8VEL0)
Organism: Mus musculus (Mouse)
Function: Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:21792907}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000305|PubMed:21792907}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Motile sperm domain-containing protein 2
Sequence:
MHQQKRQPELVEGNLPVFVFPTELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAAGAVKPQCCVDIVIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVIATLLPSAKEQQKEEEEKRIKEHLTESVFFEQSCQPENRAVSSGPSLLTVFLGVVCIAALMLPTLGDMESLVPLYLHLSVNQKLVAAYILGLITMAILRT
Protein: Kinetoplast DNA-associated protein, putative (Q38A77)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLRVSRLSLAIGTYSLFMKEQKNNPALKGLPVAKRGQATAKLYRELSVTEREELAKRAKAAPSATRKKSVPKTKGKEKVTGGGGKRKASEYTEFVKSNISKYSNLPQRERMTAVAKLWKQQKQMRSK
Protein: Glial cell line-derived neurotrophic family receptor-like, isoform G (Glial cell line-derived neurotrophic family receptor-like, isoform J) (Glial cell line-derived neurotrophic family receptor-like, isoform N) (A0A0B4K785)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
Sequence:
MLKPFAVIIGIFYLGSTIKGVVAILNCILARQLCFEDPSCSAILEIIPRVCGPIPVSCSTVTVTKCQAALRTLQAFQFFRPTCLCKEPGMDPDCNHFRDFLFDHPCGFVLKKAEKDPYPIDALPTCNHALSVCQQERKCLKLFEDFKTHCKVRDNKCKMENRDACHDSWTNLRLSPMFGCICPNNHMKKRCDRIFNIVNHNPCVDRLIFFPNGLPKLKQPRPKAKPRPKPKPKSKPKPRQRHHGMNGTELMTNNIEYHDEPNGLSDPEDEANETVDEDPGGHGDEDEDEEDDDYDDRIRAEIYSNYPHYLHPPSWGINNPLVLASHSPHTLDDDDDVVVEVVANKKPPPVTLHHHNDELDHDVVVVVDAGPHSHSHPHSHTFYSHGDQSSTTGSGLPGPAPTIPSPPNTGTKMHKTAPLGDLVAGSDITHRTYTGPSMDERVRILGMDEKLHQRIFNDNLALIDTPLIAMGSGSGSGTVTTSVSGYGLGMGMGLSGSFNYLGSMHGVPSYPFNISGFHQRHMAAAAADNEPFDIIDTGLGYGGNGNAGVYYQSGQDVEVDLSTEIIKQHFQSTCHTALDTCREDPSCSSSLQPMLTHCELHRCNRNACMSSLQAFYKGPHEDLNLDIAFCLCKKTSSQQNGNGNRHDMCMIAQEKLHPVCAQRPPDNSNPASSNGIYYHPPPACHVVADSCKEDRECRLKLEYYEQACAVDSVTKKCAGRPSGCRTAMIGILGTMLRTTCACQGTDPQHLYQCVGWRRLLWMNPCVVEAQKDFHMKRLAELGFLTTTTTTTTTTTTTTTTTTTRAPPPPPPPTTTTTTTTSMQPRQTPRKPATHIFKDVITAKEKSEPTSVEHNYLDPPDSIPLPSVNVESGGNGGNDDYHNGNGNGHGNGNGNGRRKNGGKGRGGSVDFDDPVIFVDPRETTEFVGISITEPVTTTTTTMATTTTTQPPRNCVVQRPRQSDQLIREGSSKRIYSLDDVECSELCSCGESLILTCHALCVPFAPCRTALAFYSHASPAYQAFRGRCLCYSGRFICMKPPLGEYILPGGIFLLLGYSAADEALLRPHTNLGVQDAVRALQQYVTTYIDNQTQCTLTLFNMTEENIIIAARLPHDGKLKDIELLRKEKDECTAILKTISHQINSEHSELQSHRLLSIFKMSEVEVVWPESTSAAARSGHGPGQFAGCDRLLYAAMLALAYLSSWTTLRMSDVAT
Protein: Casparian strip membrane protein 1 (LjCASP1) (P0DKC2)
Organism: Lotus japonicus (Lotus corniculatus var. japonicus)
Function: Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:24920445}; Multi-pass membrane protein {ECO:0000269|PubMed:24920445}. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Interaction partners:
Sequence:
MKSSPAELISEAKSSTQNSKMKRAVSVLDFILRLIAVVATLASAIAMGTTDESLPFFTQFIRFRAEYDDLPTLRLFVVASAFASGYLILSLPLSILHITRSSARRTRVILIILDMVMLTSLTAASSAAAAIVYLAHKGNAKANWFAFCQQYDSFCERISGSLIGSFIAIPLFIMLILFSALVLSKR
Protein: Transcription factor IIS family protein (Q9SIT3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00649}.
Interaction partners:
- BAH and TFIIS domain-containing protein
- Transcription elongation factor
- Transcription elongation factor
- Transcription factor IIS protein
- DNA-directed RNA polymerase subunit
- Probable mediator of RNA polymerase II transcription subunit 26c
- Probable mediator of RNA polymerase II transcription subunit 26b
- DNA-directed RNA polymerases II, IV and V subunit 11
- DNA-directed RNA polymerase II subunit 4
- RNApolymerase 14 kDa subunit
Sequence:
MIKNDGKMMRVRIAKERSDLCDLTAAAIKATYNTRNPCEVERCIDVLNHLKSLSLSVKDIRLSESIVKLETLRSHRNPRIRKEAQALFHSWLKTFYAHGSDNSFTAALTKDRLKMKKHVLKMCSELKKKEEPGTMARQVTAFSVLKNKEDERSQTTVEAVESKTTIKLSELNRKEDQRSLTRETEKNKARNSFLALKQKEDHRSETCVEKYFKKETKTNLKQLNMKTRRVSLEDVTTKKPHEDGSLIKKTKTEKELKKKKVDEMVKLFEAAKKAADVANAKGVLSGKPEVSRCIDALSLLMKINITPKPKEPRRMMDKLEGLTKHKDRKICHVASALLHLWRQRIREQERKKSVTKASSKTRKLSYVKIIWLEQIKVSCGFKRF