wanglab/gogpt-training-data huggingface dataset:
Protein: AP-1 complex subunit beta (Adaptor protein complex AP-1 subunit beta) (Adaptor-related protein complex 1 subunit beta) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Q54X82)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.
Subcellular location: Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}.
Interaction partners:
- Rac guanine nucleotide exchange factor B
- Uncharacterized protein
- AP-2 complex subunit sigma
- AP-2 complex subunit mu
- AP-2 complex subunit alpha-2
- Clathrin heavy chain
- AP-1 complex subunit gamma
- AP-1 complex subunit sigma-1
- AP-1 complex subunit sigma-2
- AP-1 complex subunit mu
Sequence:
MSDSKYFQTTKKGEIHELKEELLSQREDKKKEAVKKVIAAMTVGKDVSMLFTHVLNCMQTHNLELKKLVYLYVMNYAKNHPDRAILAVNTFQKDASDPNPLIRALAVRTMGCIRVDNITEHLCEPLRHALKDQDPYVRKTAAVCVAKLYDVNPELVENQGFLNILNDLLGDSNPMVVANAVASLTEIDEVSKKEVFRIHSGNLNKLLAALNECTEWGQVFILNSLCKYTPRDSQEAENVCERVAPRLQHANSAVVLSAVKVLMKYMNSIGNNDVIRLFCKKMAPPLVTLLSKEPEIQFLGLRNINLIVQKRPEILQYEMKVFFCKYNDPIYVKMEKLEIMIMLANEKNIEEVLLEFKEYATEIDVEFVRKAVRAIGRCAIKIDRASERCIQVLLDLIQTKVNYVVQEAIIVIKDIFRKYPNKYEGIIATLCANLESLDEPEAKASMIWIIGEYAERIDNAHELLNSFLEGFKDENSQVQLQLLTSIVKLFLKRPKDAQQMVQTVLNLSTQESDNPDLRDRGFVYWRLLSTDFEAAKAVVLSEKPLITDTTSHLDESLLNELILNISTLASVYHKPPETFVTKLKGLNKRGLRNKEEEDEEEPDYVDDDNMNNQQGGQQQQGGYQQQQQQQQQGGYQQQQPQQQQPKSGNLIDLDLSDLGGALPNNNNNNYGNNNNNNMYSPQPQQFNGNSNDLSFLGGGGGGGEVQAPVNKVVVFGGDRSQAIQISGAFTRFQGRINLELNLLNTSQQGMSKFKIQFYQNSFGISPADQILSCGAIEVGQSTDVTIPISCNGQISNPLNPVIDMAMMVLPSQERFYFKMNFPLLCLLTETGRLDRESYLSMWKSIPESNERSVEIQVRLPHVDVDSILRRLNSKNIFEIVRKKAPNQEISFLSCKTESSVYILIELAFNISTNTCRCSSKTTSPDIMALFEHNLNLLINNQI
Protein: Storkhead-box protein 1 (B2RQL2)
Organism: Mus musculus (Mouse)
Function: Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta (By similarity). Required for regulation of inner ear epithelial cell proliferation via the AKT signaling pathway. Involved in cell cycle regulation by binding to the CCNB1 promoter, up-regulating its expression and promoting mitotic entry (By similarity). Induces phosphorylation of MAPT/tau (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:25677106}. Cytoplasm {ECO:0000269|PubMed:25677106}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q6ZVD7}. Note=In epithelial cells, diffusely expressed in the cytoplasm, particularly in peri-membrane cortical regions (PubMed:25677106). Concentrated at centrosomes during metaphase (By similarity). {ECO:0000250|UniProtKB:Q6ZVD7, ECO:0000269|PubMed:25677106}.
Interaction partners:
Sequence:
MARPVQLAPGSLALVLSPREAGQAAGEPGGRALFRAFRRANARCFWNARLARAASRLAFLGWLRRGVLLVRAPQPCVQVLRDAWRRRALRPPRGFRITAVGDVFPVQMSPIAQCRFVPLAEVLCCAIADMNAAQVMVTQQSLLEHLIKHYPGIAVPSPDILYSTLGALIQERKIYHTGEGYFIVTPSTYFITNTPMQGNKSALLSNEGCSGPTSGTYLVSVDCCAEPTQENEALFSHCPSCQCYPDTSMCDSKDLLTAAEVTRKSQEGLEETTALTENQVVSASEDTHICVNPKPLPYTKDKGKRFGFGFLWRSLSRKEKPKAEYHSFSAQFPPEEWPVRDEDSSTKIPRDVEHALIKRINPVLTVDNLTKHTALMQKYEEQKKYNSQGTSMDILTTRHKDSSKEVIGKRQGQFAKSRRRGSSHKGRHKARSQGSELEPGNPGQEKEKQPKVPAAQPAPRTKSPSEQVHHLQGRNPAVLGSHLIYKKQINNPFQGMHLRKHSVSKGHAVQKTHGLKPTCVGPEEKPFWSAGSSDPSGVFDGEAQPPYPEQCRDKLEAGSTQVAKAPVHPVSDDFRGGPGNYPPRRVLPGPSRCCSFRESMLRPGVYHEENKDLPEVLRKSWSTCDMFLGTKEKKQALPAQRCSLDPDSSSVHAEDKTVDKILHQFQNLGLLDCPAGANRLRTHERQDGNSEELSRKALQIPEAEIVNMENEGLSDSEQDQVALSHSDPGAGDDGGCSSLCLEDDDFSETDDFCPSLPGHTQHSFAGGGTWNHLGTPAMTGKSLTDCNSKAHRLELLAIERNPWYKATGLFSNAGESPNPDLSDNPGQNSRIPWGFNYEGEPTVAHVQTPAAAAGRSLLACSTVRTTSFPVEILQESPGDRGKSPIVWRQSLPSQEMKEHFTDKLQLVKTSHGPVSAQEPQGEHLEGTENYSMTGDSGIDSPRTQSLVSTNSAILDGFKRRQHFLPNREGVQKSQNLASNSLFQLTPAINV
Protein: NEDD1 gamma-tubulin ring complex targeting factor (Protein NEDD1 isoform X1) (F1QAL1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Tubulin gamma chain
- Mitotic-spindle organizing protein 1
- Gamma-tubulin complex component
- Gamma-tubulin complex component
- Serine/threonine-protein kinase PLK
- Mitotic spindle organizing protein 2B
- HAUS augmin-like complex subunit 6
- Nucleoside diphosphate kinase 7
- Pericentrin
- Serine/threonine-protein kinase PLK4
Sequence:
MEDVTRLVSSGDCLKIWDSSSMTVVEQFNPHSATHPVAQVCWSSSNQYVVSASSIGDKLVVSSLKSSPVPVMELGEGKKQTRVSLNSTSQFLVSGGLDNTVNIWDLKTKRLHRTLKDHKEEVTCVSFNGGDSYIASGSTSGDIILHSITTNLSSKPFGHGPNVPIHDLRYSLVKRSLLGTVSDSGSVALWDANTQKELHLFEGAHKAPCSGLAFSPANDLLFVTVGLDKKIVCYDTSSKIVFRNKQVESPLTAIDFTPDGAGLVVGSTQGRIYLYDLRNLSAPVKINTAHKTSVTCIRFQNSTSKLKSTKSSSKSSQSNKRISVKLGSSQQTGPSTPTSTVPPIVSGSEFPGDGQAQVPGPSAEVFSREAEGQLSQDQMPNVEKFSSIGRNSLNLDIFSPLNDGFKSHGFADTSRNGGSIDVFSREAEGQQTADRFRVGRNSLDIFSPVRDDYKGHRLSDVSSGKKDFEYLPHFPGGSSQRKTPLGTPGSRCYSPSVVQTPPIKEEESTTTPPQQTDVQNGTKVEKSNGVRQEYDAITTPPAAQSTRIQSVQPQFNTPEPSQRRDLSTQLTYDSPISRAPASPAAAAAAAAPAAAVDSAPLTSVQMNFVRNMIHEALEDFRDTCHRDIINLQVEMVRQFYIQLNEIHGLIEKYSVNDSLVEEIERLKEENKRLRANY
Protein: Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin) (O88338)
Organism: Mus musculus (Mouse)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MISARPWLLYLSVIQAFTTEAQPAESLHTEVPENYGGNFPFYILKLPLPLGRDEGHIVLSGDSNTADQNTFAVDTDSGFLVATRTLDREEKAEYQLQVTLESEDGRILWGPQLVTVHVKDENDQVPQFSQAIYRAQLSQGTRPGVPFLFLEASDGDAPGTANSDLRFHILSQSPPQPLPDMFQLDPHLGALALSPSGSTSLDHALEETYQLLVQVKDMGDQPSGHQAIATVEISIVENSWAPLEPVHLAENLKVVYPHSIAQVHWSGGDVHYQLESQPPGPFDVDTEGMLHVTMELDREAQAEYQLQVRAQNSHGEDYAEPLELQVVVMDENDNAPVCSPHDPTVNIPELSPPGTEIARLSAEDLDAPGSPNSHIVYQLLSPEPEEGAENKAFELDPTSGSVTLGTAPLHAGQSILLQVLAVDLAGSESGLSSTCEVTVMVTDVNNHAPEFINSQIGPVTLPEDVKPGALVATLMATDADLEPAFRLMDFAIEEGDPEGIFDLSWEPDSDHVQLRLRKNLSYEAAPDHKVVVVVSNIEELVGPGPGPAATATVTILVERVVAPLKLDQESYETSIPVSTPAGSLLLTIQPSDPMSRTLRFSLVNDSEGWLCIKEVSGEVHTAQSLQGAQPGDTYTVLVEAQDTDKPGLSTSATVVIHFLKASPVPALTLSAGPSRHLCTPRQDYGVVVSGVSEDPDLANRNGPYSFALGPNPTVQRDWRLQPLNDSHAYLTLALHWVEPGEYMVPVVVHHDTHMWQLQVKVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGVLLGTLAAIGFILILVFTHLALARKDLDQPADSVPLKAAV
Protein: Sperm-associated antigen 6 (Protein PF16 homolog) (Repro-SA-1) (Sperm flagellar protein) (O75602)
Organism: Homo sapiens (Human)
Function: Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10493827}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:10493827}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9JLI7}. Note=Associated with microtubules. Detected on the sperm flagellum (PubMed:10493827). Localizes in the cilium axoneme in a SPEF1-dependent manner (By similarity). {ECO:0000250|UniProtKB:Q9JLI7, ECO:0000269|PubMed:10493827}.
Interaction partners:
- Sperm-associated antigen 16 protein
- Meiosis expressed gene 1 protein homolog
- Sperm-associated antigen 17
- Cilia- and flagella-associated protein 221
- Sperm flagellar protein 2
- Cilia- and flagella-associated protein 45
Sequence:
MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPFLYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSCYPEEIVRYYSPGYSDTLLQRVDSYQPLNN
Protein: Calmodulin-2 A (P0DP34)
Organism: Xenopus laevis (African clawed frog)
Function: Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.
Interaction partners:
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
Protein: Regulator of microtubule dynamics protein 2 (RMD-2) (mRMD-2) (Protein FAM82A1) (Q8BSE0)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cytoplasm. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. Also detected as large dots in the perinuclear region (By similarity). {ECO:0000250}.
Interaction partners:
Sequence:
MPHSTNKELILGIMAGTAGISLLAFWYHKVLKPRTTMNFPKLLSLGKKFGSLTLPEESHSAQGASVVFQRRQLQILEKLNELLTNMEELKEEIRFLKETIPKLEECIQDEFGGKVTVHKISPQHRARKKKGTTVQRSATSNSSEEAESEGGYITANTDTEEQNFPFPKALNTHIEELKLDVLLQKADHLRTNESHKMESFELLCDHKEKFSEETEFLWRLARAYGDMYDLSTSTQEKKHYANIGKTLGERAITRAPMNGHCHLWYAVLCGYVSEFEGLQNKINCGHLFKKHLEIAIQLLPEEPLLYYLKGRYCYTVSRLSWIEKKMAATLFGEIPYSTVHEALHNFLKTEELQPGYSMSNYMYTAKCYVELGEPQEACKFCNLALLLPVVTKEDKDAHKEVKKMISSLKR
Protein: Cobra1 protein (Cofactor of BRCA1) (Negative elongation factor B) (Q7ZVU3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MFAGLPELGISNGEDLKETLTNCTEPHKAIDQFQTENGILLPTLQSALPFLDLHGTPRLEFHQSVFDELRDKLMERVATIAEGKEEDRYVKLEELLEKSFPLVKMPSIQPVVMQVLKHLPKVPEKKLKQVMADKELYKVCAVEVKRQIWQDNQALFGDEVSPLLKQYIVEKEAALFSNDLSILHNFFSPSPKTRRQGEVVLKLTQMIGKNVKLYDMVLQFLRTLFLRTRNVHYRTLRAELLMSLHDLDISEICSVDPCHKFSWCLDACIREKFVDAKRARELQGFLDGVKKGQEQVLGDLSMILCDPFACNTLVLSTVRNLQELLSQDALPRDSPDLLLLLRMLSLGQGAWDMIDSQVFKEPRMDLEVVTRFLPAMMSIVVDDYTFTVEQKLPSEEKTSLAYPTTLPETFSRYILDNRVACEIGLYYALHIAKLRNKNALQRLLPALVDTYNDMAFGDIFLHLLTGHLTLLSDEFGTEGFCTAVFDNFLLTSFSSKENVHRHCLRLLNHLHQKVLPTYMETLMKTLEPPKQSSESVKELYNLLKEKLEASKKSPPQPEEAPSLDLGLHPVTVPPTPSTPTTPV
Protein: SUMO1 activating enzyme subunit 1 (M0QX65)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTT
Protein: EDAR associated via death domain (F1LYE0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Tumor necrosis factor receptor superfamily member EDAR
- TNF receptor-associated factor 6
Sequence:
MASPDDPLRSDHMAKEPVEDTDPSTLSFAMSDKYPIQDTGLPKAKECDAVTSNCPPNSDDQHQGEENDFPDSTGDPLSGVSRNQPCKEGCPCSSCSPRAPTISDLLNDQDLLDVIRIKLDPCHPTVKNWRNFASKWGMPYDELCFLEQRPQSPTLEFLFRNSQRTVGQLMELCRLYHRADVEKILRRWVDEEWPHRGPLDGSMHF
Protein: Prephenate dehydrogenase (P73906)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Prephenate dehydratase
- 3-dehydroquinate synthase
- Histidinol-phosphate aminotransferase
- Chorismate synthase
- Aspartate aminotransferase
- Indole-3-glycerol phosphate synthase
- Tryptophan synthase alpha chain
- Purine nucleoside phosphorylase slr1573
- Anthranilate synthase component 1
Sequence:
MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQLVDEAGQDLSLLQTAKIIFLCTPIQLILPTLEKLIPHLSPTAIVTDVASVKTAIAEPASQLWSGFIGGHPMAGTAAQGIDGAEENLFVNAPYVLTPTEYTDPEQLACLRSVLEPLGVKIYLCTPADHDQAVAWISHLPVMVSAALIQACAGEKDGDILKLAQNLASSGFRDTSRVGGGNPELGTMMATYNQRALLKSLQDYRQHLDQLITLISNQQWPELHRLLQQTNGDRDKYVE
Protein: S-adenosylmethionine synthase (EC 2.5.1.6) (Q2U2Q7)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Interaction partners:
- RmlD-like substrate binding domain-containing protein
- 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
- Hcy-binding domain-containing protein
- adenosylmethionine decarboxylase
- Aminotransferase class I/classII large domain-containing protein
- DNA
- S-adenosylmethionine synthase
- aromatic-amino-acid transaminase
- GAF domain-containing protein
- aromatic-amino-acid transaminase
Sequence:
MGSVANLPKSGTFLFTSESVGEGHPDKIADQVSDAILDACLAEDPLSKVACETATKTGMVMVFGEITTKAQLDYQKVIRGAIQDIGYDSSEKGFDYKTCNVLVAIEQQSPDIAQGLHYDEALEKLGAGDQGIMFGYATDETPELLPLTVILSHKLNKAMTDARKNGTIPWLRPDTKTQVTIEYAHDNGAVKPLRVDTVVISAQHSDDLSTEEIRVALKEKIIKQVIPAELLDDRTVYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYSKVDRSAAYVARWVAKSLVNAGLARRALVQLSYAIGVAEPLSVFVETYGTSQKSSEELVQIVRNNFDLRPGVIVKELDLAKPIYFQTAKNGHFTNQEFSWEKPKTLKF
Protein: Membrane-spanning 4-domains subfamily A member 3 (CD20 antigen-like protein) (Hematopoietic-specific transmembrane protein 4) (HTm4) (Q96HJ5)
Organism: Homo sapiens (Human)
Function: Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).
Subcellular location: Endomembrane system {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Located in the perinuclear area.
Interaction partners:
- B-lymphocyte antigen CD20
- Myeloperoxidase
- Defensin alpha 4
- Eosinophil cationic protein
- Neutrophil elastase
- Cell adhesion molecule CEACAM8
- Myeloblastin
- Cathepsin G
- Azurocidin
- Bactericidal permeability-increasing protein
Sequence:
MASHEVDNAELGSASAHGTPGSEAGPEELNTSVYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFFTFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSSESPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSPPNSV
Protein: Glucose-methanol-choline oxidoreductase (Eurofung) (C8VER6)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MGSIADPENTYDYIVCGGGTSGCVVAGRLAENKDVRILLLEAGQHNRDLENVHMAGGWSNNFDSETDWNLITKPMAGVDNRQVKLSRGRFLGGSSGCNGTLCIRGSKQDYDDWGLEGWSGDEFFEAMKKSETFHGKPWFKADESAHGYSGPLHTEPHDLAPIADRLIDSFVDQGLPLHHDMFSTGDVPHGCGHVPRTVYKGVRTTSADFITKEYDRTNITIQTDATVDRIIIERKDDGLRAVGALTRSADGTSKAYYARREVIVSGGAYCSPAILMRSGIGARDELAQFGIDCLVDLPGVGKNLMDHLIVFIFYEASKSGLTNCDKVYHDNALEKALQEYREHKTGFLSTFPFGSFAFARLDDRLKDEPLWRDAPRLPGRDPMGLTPKQPNIEFFSTETYGGPKQYNQFPIDHKHAFSIIAELFSPKSRGTVTLASADPLQNPVIDCNYLDHPLDLLVLSEACRFANEIVTKGAGTKDIVKGSWPENLDHHTYTTREQWVPYVKEHATTCYHAAGTCAMGKPDDPNAVLDNKLRVRGVKGLRVADCSIMPTLHGGHTQMPAYGIGERCADFIKEEW
Protein: Disease resistance protein (TIR-NBS-LRR class) family (Disease resistance protein-like) (Q9FHF4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Pentatricopeptide repeat-containing protein At5g46460
- Protein DA1-related 5
- Uncharacterized protein At5g49220
- GDSL esterase/lipase At1g31550
Sequence:
MASSRNWVYDVFPSFSGTDVRRNFLSHLLKGLHKSVNSFRDQNMERSQSLDPMLKQAIRDSRIALVVFSKNYASSSWCLNELLEIVKCKEEFGQMVIPIFYCLDPSHVRHQDGDFGKNFEETCGRNTEEEKIQWEKALTDVANLAGFDSVTWDDEAKMIEEIANDVSGKLLSTSSTDSAENSIGIEDHIANMSVLLQLEAEEVRMVGIWGSSGIGKTTIARALFNQLSRHFPVSKFIDRAFVYKSRETYKGANPDDPNMKLHLQGCFLSEILGKKDIKIDHLGALGERLKHQKTLIIIDDLDDLVVLDSLVGKTNWFGCGSRIIVITNNKQFLRAHGIDHIYEVSLPSKERAQEMFCQSAFGENSPPEGFEELVVEIAWLAGSLPLGLTVFGSALRGRKKEYWVKMLPRLQNDLDGNIEETLKVSYDAIGNVKDQALFRLIACLFNHVKVRDIELLLADSGLDVNIALENLVDKSLIHVRNDHVEMHRLLQETGRNIVRSQSTDNPGEREFLVDSNDSRTVLSEGIGTRKVLGISLDTSKVSEFCVHENAFKGMGNLLFLDISSKTFIEEEVKVHLPEKINYYSVQPKQLIWDRFPLKCMPYTFLRNLVKLEMHDSKLEKLWEGAMSFTCLKELDMWASKYLKEIPDLSKATNIEKLDFGHCWSLVELPSSIRNLNKLLELNMEYCGELETLPTGFNLKSLDYLNFNECWKLRTFPEFATNISNLILAETSIEEYPSNLYFKNVRELSMGKADSDENKCQGVKPFMPMLSPTLTLLELWNIPNLVELSSSFQNLNNLERLDICYCRNLESLPTGINLESLVSLNLFGCSRLKRFPDISTNIKYLDLDQTGIEEVPWQIENFFNLTKLTMKGCRELKCVSLNIFKLKHLGEVSFSNCGALTRVDLSCYPSGVEMMKADNADIVSEETTSSLPDSCVLNVNFMDCVNLDREPVLHQQSIIFNSMILPGEEVPSYFTYRTSDSQPFGTSSSLPIPLLPTQLSQPFFRFRVCAVVSASNGVYIGVYSRFKGRIGNKFDSFGELHKFMEIEKGIHLCIFDCRIRLYKDNVPLSQLNYDHVDINIHITSGDWRSTVVLKEWGIRLLEDCSSAENRLGNPNSTLPHVCVEDEENLVNGTEQGDRGDVVTETSSKQNEDVILLQRSADSMFSRMSGKEMISYFTHRTTGTSLTNIPLPHTSPSQPFFRFKAFAVVGCKSSGQFSYFVTHISCRFKDGFENQPRRLYKAENGNHLDIYECSFPLYQGNASPAEMNYDRVDIQLHLRYRSDSTVRLIVWGIRLIEDCSSSENQLDSETDQFEECGNSDIGHEIDQSEECEDMDDTGGICIGIDQSEERGDSDE
Protein: Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4) (P02651)
Organism: Rattus norvegicus (Rat)
Function: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Subcellular location: Secreted.
Interaction partners:
- Apolipoprotein B-100
- Apolipoprotein C-III
- Apolipoprotein E
- Apolipoprotein A-II
- Apolipoprotein C-I
- Apolipoprotein A-I
- Apolipoprotein C-II
- Clusterin
- Beta-2-glycoprotein 1
- Apolipoprotein C-IV
Sequence:
MFLKAVVLTVALVAITGTQAEVTSDQVANVMWDYFTQLSNNAKEAVEQLQKTDVTQQLNTLFQDKLGNINTYADDLQNKLVPFAVQLSGHLTKETERVREEIQKELEDLRANMMPHANKVSQMFGDNVQKLQEHLRPYATDLQAQINAQTQDMKRQLTPYIQRMQTTIQDNVENLQSSMVPFANELKEKFNQNMEGLKGQLTPRANELKATIDQNLEDLRSRLAPLAEGVQEKLNHQMEGLAFQMKKNAEELQTKVSTNIDQLQKNLAPLVEDVQSKLKGNTEGLQKSLEDLNKQLDQQVEVFRRAVEPLGDKFNMALVQQMEKFRQQLGSDSGDVESHLSFLEKNLREKVSSFMSTLQKKGSPDQPLALPLPEQVQEQVQEQVQPKPLES
Protein: Cecropin-C (O16829)
Organism: Drosophila melanogaster (Fruit fly)
Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
Subcellular location: Secreted.
Interaction partners:
- Cecropin-B
- Nuclear factor NF-kappa-B p110 subunit
- Diptericin B
- Attacin-A
- Dorsal-related immunity factor Dif
- Metchnikowin
- Diptericin A
- Drosocin antimicrobial peptides
- Defensin
- Attacin-C
Sequence:
MNFYKIFVFVALILAISIGQSEAGWLKKLGKRIERIGQHTRDATIQGLGIAQQAANVAATARG
Protein: Protein FRIGIDA (P0DH90)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the regulation of flowering time in the late-flowering phenotype. Involved in the enrichment of a WDR5A-containing COMPASS-like complex at the 'FLOWERING LOCUS C' that trimethylates histone H3 'Lys-4', leading to FLC up-regulation and RNA levels increase. Variants with an early-flowering phenotype (Including cv. Columbia, cv. Landsberg Erecta and cv. Wassilewskija) show loss-of-function mutations of FRI. Able to delay flowering independently of FRL1 activity. Dispensable for the reactivation of FLC in early embryogenesis, but required to maintain high levels of FLC expression in later embryonic and vegetative development. Suppresses the repression of FLC by the autonomous pathway, but has no effect on the expression of the genes involved in this pathway.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:17138694}.
Interaction partners:
Sequence:
MSNYPPTVAAQPTTTANPLLQRHQSEQRRRELPKIVETESTSMDITIGQSKQPQFLKSIDELAAFSVAVETFKRQFDDLQKHIESIENAIDSKLESNGVVLAARNNNFHQPMLSPPRNNVSVETTVTVSQPSQEIVPETSNKPEGGRMCELMCSKGLRKYIYANISDQAKLMEEIPSALKLAKEPAKFVLDCIGKFYLQGRRAFTKESPMSSARQVSLLILESFLLMPDRGKGKVKIESWIKDEAETAAVAWRKRLMTEGGLAAAEKMDARGLLLLVACFGVPSNFRSTDLLDLIRMSGSNEIAGALKRSQFLVPMVSGIVESSIKRGMHIEALEMVYTFGMEDKFSAALVLTSFLKMSKESFERAKRKAQSPLAFKEAATKQLAVLSSVMQCMETHKLDPAKELPGWQIKEQIVSLEKDTLQLDKEMEEKARSLSLMEEAALAKRMYNQQIKRPRLSPMEMPPVTSSSYSPIYRDRSFPSQRDDDQDEISALVSSYLGPSTSFPHRSRRSPEYMVPLPHGGLGRSVYAYEHLAPNSYSPGHGHRLHRQYSPSLVHGQRHPLQYSPPIHGQQQLPYGIQRVYRHSPSEERYLGLSNQRSPRSNSSLDPK
Protein: Kinesin-like protein (C8V3Q8)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Kinesin-like protein
- Uncharacterized protein
- Dis1/XMAP215 protein AlpA
- Kinesin-like protein bimC
- MAP65/ase1 homolog
- Clip 170 homolog
- EB1 homolog
- Uncharacterized protein
- Kinesin class 4
- Probable kinetochore protein ndc80
Sequence:
MSTLPQPSRTASGPPLGAAAQLPIPKSRKSLPTSVESPRAVSPSKLRTPSSPRPTLSKSPLSNSATNISAARSTTVARTPSSPDKSLRRTISIAAFPQPPRPGSRPSTASSMTAPHGLQSSGSVKSKRGSRPSAGTTSQRSSKTHSLLSVGAAVPGTDMEASPSQSRSSSAEGSYSTSATTFDEGEPASTKSKETKGNVIVSVRVRPNVGGESSANPEWIVDARRGLLVYNGKEGGDYYYDNVFSAMENNARVYDSAAKRLVRRVMEGYHGTVFAYGMTGTGKTFSMQGTATSPGVIPLAITDIFSFIRETPHREFLLRVSYLEIYNEKIHDLLSASTGSSSEDIKLREDSKRGVYATPLKEEIVQSPTQLLRVIARGDHARRTGSTQFNARSSRSHAVVQIVVESRERVPTGTTQDRRSGLAPGGVRVSTLSLIDLAGSERAADDKERRTEGAHINKSLLTLGNIISRLSETKGKTAADKDGKHLPFRDSKLTRLLQPALSGNSLVSILCTVQLSSLVASETLNTLKFAARAKNNIVSHAKRAEEAFGGGGGDAGSRVLLERYRMEIQALRCQLENQTKAQAEKELKLEEQKLEQEAQERHEEQMLEMQLARTALKERIEHLNRLILSSKSTGVNSQGAMSALGRLSRLSSIDPGSRSLRSSVSQSTLGTSMRPVSFLSVHSQEFHLSNEDEDTIGEFADGKASAQRQIAALQADLADKNRYIATLERRLLQARRSSHSRMSLGIKANSSTDNPNFVAQLREKDMEINELRLQLDDKDRMLTALRSAARHRDLAQLTLDNQSLPKETSSPDREPPPTSQAPDPGAKRKSMDEVSRILDEMIQDRVESGHLIKGARGSVRVAPGSRRASESHQAAGPTGTTPLNSRPSA
Protein: CASP-like protein 1A1 (AtCASPL1A1) (Q9XI72)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:24920445}; Multi-pass membrane protein {ECO:0000269|PubMed:24920445}.
Interaction partners:
- GDSL esterase/lipase At1g74460
- Cytochrome b561 and DOMON domain-containing protein At4g17280
- GDSL esterase/lipase At1g28650
- GDSL esterase/lipase At2g30310
- Cytochrome b561 and DOMON domain-containing protein At5g47530
- GDSL esterase/lipase At5g45960
- GDSL esterase/lipase At5g37690
- GDSL esterase/lipase At2g23540
- CASP-like protein 4B1
- Uclacyanin 1
Sequence:
MEEAKHNEAEEAQGIEAREAKQIEAGETSRSSRKLITFEPKLVINKGISVLGFVLRLFAVFGTIGSALAMGTTHESVVSLSQLVLLKVKYSDLPTLMFFVVANAISGGYLVLSLPVSIFHIFSTQAKTSRIILLVVDTVMLALVSSGASAATATVYLAHEGNTTANWPPICQQFDGFCERISGSLIGSFCAVILLMLIVINSAISLSRH
Protein: F-box and leucine-rich repeat protein 18 (Q4V8X1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MNNQIETAQCCSDNISQVSVTISDFSDEILLNILRFIPSHDLILNVSRVCRKLRTLCLDKSLRVHVHLHKEYTANDDAVKQLLKVISADIQTLNLNGCYWLAGSTVDQVTRCKSLVSLDLSGCRLTSVRLSHLLSSLSSLKSLALDVGPGFDLHQLSAEGKSALARLQELKQTLLTPSYGVVPCCSALRRLHLYLEASEVWREAGGCAQLMVGQSSVPHYQNLRWFSARLAPGEVNRTLLALYLAVFSMRVPEGLTGLVLSVPGPAPPPPVAMTALMESMASTVGNTVSALQLPRTWLDGAILGRVLAHGCPAYLNVSRCSSPGFNPLHVLLSAGRDLTPLRSLNLRGCGRGPLSESCGKGDEEMDTDSVKALAECCPHLNHLNLSATHYHHNLSTGQDGHLCGTLGRLTGLCSLALPVCALAQSPPTQINNQDSNTDLASRSLLLGLKKTTRIGVPTYRPTSEIAVGQGEERTDRGLCIQPLLQGCPYLVELELIGAGFSSAMPRNEPAIRKDPAACSWSYSVGDGELAALGGMKFLRKLTLAHLPGVLKGTGLIELLQGCKDLHSLSLANLGSLKTMNYTQALLEALSYCTQLRELRLEQPYFNANAAFFEALSQCGQLRRLCLVSRHGTFQPAAVTAFMQSCSDVIMCHMFMGGTLVACKTLQKTLLDSFSVSRPALSVVIYPLLHEDLAHVIRGMPLCHLDEMTLFKSRVAEEPMRR