wanglab/gogpt-training-data huggingface dataset:
Protein: Wall-associated receptor kinase-like 6 (EC 2.7.11.-) (Q8GXQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
Subcellular location: Membrane {ECO:0000269|PubMed:14576286}; Single-pass type I membrane protein {ECO:0000269|PubMed:14576286}.
Interaction partners:
Sequence:
MKKTKTYQVFCIAALSVLTLQLINGSSAATPPPPNSNSSTSCNRACGGVSIPFPFGIGKDCYLNGWYEVICNTSTSGSSGTTVPFLSRINSEVVNISLPDGKKLYGVVHIKGPVTSLGCSSSSSSSQVSEMSLPNLNVTGRGSPYFLTDENCLVMVGCGTKALMKDIESEILGCESSCEDSKSSEEVTNSKCDGYKCCQARIPLERPQVIGINIENTSATRGKEGCSVAFLTNKRYAPMNVTEPEQFHAGGYAVVELGWYFDTSDSRYRNPLGCRNMTRYSSYSSFDKCSCEYDYFSGMSYRICYCNYGYTGNPYLRHGCIDIDECEGHHNCGEGTCVNMPGTHSCEPKITKPEKASVLQGVLISLGVLLFVLGILGLYKFIKKRTRIIRNKNFFKRNGGLLLKQQLITKNGNVDMSRIFSSKELKKATDNFSMNRVLGQGGQGTVYKGMLAEGRIVAVKRSKVVGEGKMEEFINEVVLLSQINHRNIVKLLGCCLETEVPVLVYEYIPNGDLFKRLHEKSESNDYTMTWEVRLRIAIEIAGALSYMHSAASIPIYHRDIKTTNILLDEKYRAKVSDFGTSRSITIAQTHLTTLVAGTFGYMDPEYFLSSQYTDKSDVYSFGVVLVELITGEKPLSRKRIGN
Protein: Neurosecretory protein VGF (VGF8a protein) [Cleaved into: VGF(24-63); VGF(180-194); VGF(375-407); Neuroendocrine regulatory peptide-1 (NERP-1); Neuroendocrine regulatory peptide-2 (NERP-2); VGF-derived peptide TLQP-11; VGF-derived peptide TLQP-21; VGF-derived peptide TLQP-30; VGF-derived peptide TLQP-62; VGF-derived peptide HFHH-10; VGF-derived peptide AQEE-30; VGF-derived peptide LQEQ-19] (P20156)
Organism: Rattus norvegicus (Rat)
Function: Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-specific manner. VGF and peptides derived from its processing play many roles in neurogenesis and neuroplasticity associated with learning, memory, depression and chronic pain (By similarity).
Subcellular location: [Neurosecretory protein VGF]: Secreted {ECO:0000250|UniProtKB:O15240}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:O15240}. Note=Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus. {ECO:0000250|UniProtKB:O15240}.
Interaction partners:
- Secretogranin-2
- Secretogranin-1
- AP-1 complex subunit gamma
Sequence:
MKTFTLPASVLFCFLLLIRGLGAAPPGRSDVYPPPLGSEHNGQVAEDAVSRPKDDSVPEVRAARNSEPQDQGELFQGVDPRALAAVLLQALDRPASPPAVPAGSQQGTPEEAAEALLTESVRSQTHSLPASEIQASAVAPPRPQTQDNDPEADDRSEELEALASLLQELRDFSPSNAKRQQETAAAETETRTHTLTRVNLESPGPERVWRASWGEFQARVPERAPLPPSVPSQFQARMSENVPLPETHQFGEGVSSPKTHLGETLTPLSKAYQSLSAPFPKVRRLEGSFLGGSEAGERLLQQGLAQVEAGRRQAEATRQAAAQEERLADLASDLLLQYLLQGGARQRDLGGRGLQETQQERENEREEEAEQERRGGGEDEVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEEAPGHRRKDAEGTEEGGEEDDDDEEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPPPAPARDELPDWNEVLPPWDREEDEVFPPGPYHPFPNYIRPRTLQPPASSRRRHFHHALPPARHHPDLEAQARRAQEEADAEERRLQEQEELENYIEHVLLHRP
Protein: Uncharacterized protein (Q728Z3)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Uncharacterized protein
- DNA-directed RNA polymerase subunit alpha
- DNA gyrase subunit A
- DNA-directed RNA polymerase subunit beta
- FG-GAP repeat protein
- Zinc finger/thioredoxin putative domain-containing protein
- Leucine-binding protein domain-containing protein
- histidine kinase
- Enolpyruvate transferase domain-containing protein
- GAF domain protein
Sequence:
MLDSQWRTAPPEKGEFLAFSLRLDTRRIPAAVIKKYTALSLRDEEERNKQQGKKFISRERKKELKEQVKLRLLSRFLPIPAEFNVVWATTSNMVYFASTQSKMCDLFMEYFTLTFDLHLEAMTPYQLAASMLDENAMSRLDIIEATQFA
Protein: R-linalool synthase QH1, chloroplastic (EC 4.2.3.26) (Q9SPN0)
Organism: Artemisia annua (Sweet wormwood)
Function: Monoterpene synthase that catalyzes the formation of (3R)-linalool from geranyl diphosphate, but not from isopentenyl diphosphate, dimethylallyl diphosphate, chrysanthemyl diphosphate, farnesyl diphosphate, (+)-copalyl diphosphate or geranylgeranyl diphosphate.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
GNAYMRIYSTKTTRITANATVNAADTHVRRSANYKPSSWSFDHIQSLSSKYTGDDYVARANTLKDAVKTMIRKSGNSLRTLELVDELQRLGISYLFEEEISNLLETIYYNYYKFPENWNKINLNLKALGFRLLRQHGYHVPQEIFLNFKDKNQNLNSYLLNDVVEMLNLYEASYHSFEDESILDDARDITTKYLKESLEKIDGSIFSSVTHALEQPLHWRVPRVEAKWFIELYEKKNGMSPTLVELAKLDFDMVQAIHLEDLKHASRWWRDTSWDTKLTFARDLIVENFLWTIGFSYLPNFSRGRRTITKVAVMITTLDDVYDVFGTLGELEQFTDVINRWDIKAIEQLPDYMKICFLGLYKSINDITHETLANKGFLILPYLKKAWADLCKAYLVEAQWYHRGHIPTLNEYLDNACVSISGPVALMHVHFLTSVSSIEEIHQCIQRTENIVHYVSLIFRLADDLGTSLGEMERGDTLKSIQLHMHETGATEPEARSYIKLLINKTWKKLNKERATVNSESSQEFIDYATNLVRMAQFMYGEGDEDFGLDVIKSHVLSLLFTPIQGI
Protein: LD44762p (Rab8) (Rab8, isoform C) (O18338)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Rab GDP dissociation inhibitor
- FI07418p
- Exocyst complex component 6
- Guanine nucleotide exchange factor MSS4 homolog
- Exocyst complex component 5
- Exocyst complex component 4
- Intraflagellar transport 20
- Rab proteins geranylgeranyltransferase component A
- Exocyst complex component 3
- Exocyst complex component 1
Sequence:
MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSRTKDSWLSRCSLL
Protein: ATP-dependent Clp protease proteolytic subunit 1, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp) (Q27539)
Organism: Caenorhabditis elegans
Function: Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:17925224}.
Interaction partners:
- ATP-dependent Clp protease ATP-binding subunit clpX-like
- ATP-dependent Clp protease ATP-binding subunit clpX-like
- Lon protease homolog, mitochondrial
- Homeobox protein dve-1
- Chaperonin homolog Hsp-60, mitochondrial
- Heat shock protein hsp-6
- Stress activated transcription factor atfs-1
- Probable NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Mitochondrial Ribosomal Protein, Large
- AFG3-like protein spg-7
Sequence:
MLRRLVTSSLSASRSMSASVQSRVGIPFVIDNEGKGERTYDIYSRLLRDRIVCLMTPVDDFIASALIAQLLFLQSESGKKPIHMYINSPGGSVTAGLAIYDTIQMISAPVSTWVIGQASSMGSLLLCAGEKGMRSALPNSRIMVHQPSGGAQGTCSDIVIRAEEITRLKRRLNEIYVHHTGMSYDEIEKTLDRDRFMSAHEALKFGLVDQIETHNGSMPSD
Protein: Retinoic acid early-inducible protein 1-beta (RAE-1-beta) (O08603)
Organism: Mus musculus (Mouse)
Function: Acts as a ligand for KLRK1.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10894171, ECO:0000269|PubMed:8982867}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:10894171, ECO:0000269|PubMed:8982867}.
Interaction partners:
Sequence:
MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKDPTPADPLWYEAKCFVGEILILHLSNINKTMTSGDPGETANATEVKKCLTQPLKNLCQKLRNKVSNTKVDTHKTNGYPHLQVTMIYPQSQGRTPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWKDDGEFVKQLKFLIHECSQKMDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFISLLFAFAFAM
Protein: Zinc finger protein 322 (Zinc finger protein 322A) (Q8BZ89)
Organism: Mus musculus (Mouse)
Function: Transcriptional activator. Important for maintenance of pluripotency in embryonic stem cells. Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes. Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly. Promotes inhibition of MAPK signaling during embryonic stem cell differentiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:24550733}. Cytoplasm {ECO:0000269|PubMed:24550733}. Note=Mainly found in the nucleus. {ECO:0000269|PubMed:24550733}.
Interaction partners:
Sequence:
MENHLGENHRRCTLQKRNVTRELKKGKHTMYALKRVKKIYIRVHEITQIDNQTYQCLEREQNFCENLARMCERTYTEEKPYRCDMCEKTFIQSSDLISHQRIHNYEKPYKCSKCEKSFWHHLALSGHQRTHAGKKFYTCDICGKNFGQSSDLLVHQRSHTGEKPYLCNECDKCFSRSTNLIRHRRTHTGEKPFKCLECEKAFSGKSDLISHQRTHTGERPYKCNKCEKSYRHRSAFIVHKRVHTGEKPYKCGACEKCFGQKSDLIVHQRVHTGEKPYKCLECMRSFTRSANLIRHQATHTHTFKCLEYEKSFNCSSDFIVHQRIHMEEKPHQWSMCESDFLLGMDFVAQQKMRAQTEELHYKYSVCDKTFHHSSALLQHQTVHIDDEYICNMSEKGLDLSSHASETSRVS
Protein: Nuclear pore complex protein Nup75 (75 KDa Nucleoporin) (Nucleoporin Nup75) (Nucleoporin Nup85) (A1YK02)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Required for nuclear import of phosphorylated Mad via importin msk. Has no role in classical nuclear localization signal (cNLS)-dependent nuclear import via importin-beta. Facilitates the interaction between Nup93 and sec13 with msk.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q9BW27}. Nucleus membrane {ECO:0000250|UniProtKB:Q9BW27}.
Interaction partners:
- Nucleoporin Nup37
- Nuclear pore complex protein Nup160 homolog
- Nucleoporin 43kD
- Protein SEC13 homolog
- Nuclear pore complex protein Nup133
- Nuclear pore complex protein Nup107
- Nucleoporin seh1
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein Nup205
- Nuclear pore complex protein Nup154
Sequence:
MSDSGVFAFELGDDLATRCGNTLTGVFVPGSRIALSAYRHVTHSSRDEPTENAGQVPVLIYMAQESTLFDEPVLRSVLAEANATFATLQQLGSRATRAEYVNISRAYRSIVRSCLEKLEQAKKSPEVQTDEARLQRLCDAIVVFYAAECLWHLFEILYIQSNQLVVPQLLDWARFHSPHAEDRATDLLLMGEEASESDDYWSIVKSLIMLGEIDVTRAVLSQNRKAGQTSFKAAEQILKSMPVYQEGYALQKFHSQWEFWHVDTERKIQSGLFATEPELEQLIRLVAGDSEQWDAGIKESQDFYEYLPGYLLFTKPTCKPFELKIAAAKWLNRWCLLRPEREQCSMNRMVSQLMDHDLRLFIYDAQKLNDTHWFSTHLIDLIHHCGQLKSYFDQNNIDLPALRHSMIYEYGSYLMTSHNMWQLGIDYLDCCKQEGQAAIELLLPRITLRSERQATKLINLARQRGLISVEREICKVLSKRSYDNERYGNALEWAIRSKDVLLVTAVADFILKHYSKTGCMLCPDTIANVGGRMFASPRLVFLSKYFEFYEFYRTRDFLSASELLVNLLESKITPDYFWPSLLIDSMPLLESKDPKIFAKETVAILHHIETDLVPIIERDVSKYGKHHTETVFKDYRVENVDEIMNLLRLACARNLARALIIENTLPVV
Protein: Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into: Dickkopf-related protein 4 short form] (Q9UBT3)
Organism: Homo sapiens (Human)
Function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Subcellular location: Secreted.
Interaction partners:
- Low-density lipoprotein receptor-related protein 5
- Low-density lipoprotein receptor-related protein 6
- Kremen protein 1
- Protein Wnt-6
- Protein Wnt-2b
- Dickkopf-related protein 1
- Dickkopf-related protein 2
- Protein Wnt-3a
- Protein Wnt-2
- Kremen protein 2
Sequence:
MVAAVLLGLSWLCSPLGALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
Protein: Lipoprotein LpqH (19 kDa lipoprotein antigen) (Putative transporter LpqH) (A0A0H3M9Z0)
Organism: Mycobacterium bovis (strain BCG / Pasteur 1173P2)
Function: Might be involved in ligand transport. A host TLR2 agonist, modifies host gene expression in response to pathogen.
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}. Host cytoplasm {ECO:0000269|PubMed:11123323}. Extracellular vesicle, bacterial extracellular vesicle {ECO:0000269|PubMed:21364279}. Note=Following infection of mouse macrophage cell line J774A.1 by live (not heat-killed) bacteria the protein is detected in host cytoplasm at 1 hr but has decreased dramatically by 3 hrs (PubMed:11123323). Also present in bacterial extracytoplasmic vesicles, both in mouse macrophages and in culture media (PubMed:21364279). {ECO:0000269|PubMed:11123323, ECO:0000269|PubMed:21364279}.
Interaction partners:
Sequence:
MKRGLTVAVAGAAILVAGLSGCSSNKSTTGSGETTTAAGTTASPGAASGPKVVIDGKDQNVTGSVVCTTAAGNVNIAIGGAATGIAAVLTDGNPPEVKSVGLGNVNGVTLGYTSGTGQGNASATKDGSHYKITGTATGVDMANPMSPVNKSFEIEVTCS
Protein: Forkhead box protein J2 (Fork head homologous X) (Q9ES18)
Organism: Mus musculus (Mouse)
Function: Transcriptional activator. Able to bind to two different type of DNA binding sites (By similarity). Plays an important role in spermatogenesis, especially in spermatocyte meiosis.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- POU domain, class 3, transcription factor 2
- MHC class II regulatory factor RFX1
Sequence:
MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGGARKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVPGSGEASLSHEGTPQMSLQSPSSVANYSQGPGSVDGGAVAAGAPGQESTEGAPPLYNTNHDFKFSYSEINFQDLSWSFRNLYKSMLERSSSSQHGFSSLLGDMPPSNNYYVYQQQQQQQPPPQPQPPPQQPQPQQQQAPTQGPSNVGGAPPLHTPSPDGCTTPGGKQAGAEGYGPPTGMAMHPPPLQHGGYHPHQHHPHSHPAQQPPQPQAQSQASINSTGFAFPPDWCSNIDSLKESFKMVNRLNWSSIEQSQFSELMESLRQAEQRNWTLDQHHIANLCDSLNHFLTQTGHMPQQGGSHRPPAPSRITDSCALTSGKPEPSMNQVNSYGHPQASHLYPGPAPMYPISTQDSAGYNRPAHHMVPRPPVPPPGANEEITDDFDWDLIT
Protein: Adenosine kinase (ADK) (AK) (EC 2.7.1.20) (P9WID5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the phosphorylation of adenosine to adenosine monophosphate (AMP). Can also catalyze the phosphorylation of the adenosine analog 2-methyladenosine (methyl-Ado) to methyl-AMP, the first step in the metabolism of this compound to an active form that displays antitubercular activity. Is not active on guanosine, inosine, deoxyadenosine, cytidine, uridine, or thymidine. Prefers dGTP and GTP to ATP as phosphate donors in vitro.
Interaction partners:
- Adenosine deaminase
- Adenylate kinase
- Adenine phosphoribosyltransferase
- Adenylosuccinate lyase
- Purine nucleoside phosphorylase
- Probable nucleoside hydrolase IunH
- cAMP/cGMP dual specificity phosphodiesterase Rv0805
- Possible deaminase
- Ribokinase
- Uncharacterized protein Rv2203
Sequence:
MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIHVGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDYEAAASRLAGAYGEHAAAEIVAVLA
Protein: Forkhead box protein O1-A (A3RK74)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor that regulates metabolic homeostasis in response to oxidative stress (By similarity). Binds to the consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3' (By similarity). Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism (By similarity). May be involved in regulating cellular homeostasis in the eye.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9R1E0}. Nucleus {ECO:0000250|UniProtKB:Q9R1E0}. Note=Shuttles between the cytoplasm and nucleus. {ECO:0000250|UniProtKB:Q9R1E0}.
Interaction partners:
- histone acetyltransferase
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- Non-specific serine/threonine protein kinase.
- Signal transducer and activator of transcription
- cyclin-dependent kinase
- V-akt murine thymoma viral oncogene homolog 2,-like.
- non-specific serine/threonine protein kinase
- Mothers against decapentaplegic homolog 2
- Mitogen-activated protein kinase
Sequence:
MADAAQNQMVEIDPDFEPLSRPRSCTWPLPRPEFPNPAAADSNTSSPAPSVKQEPSSTADFINNLSLLEENEDYPDQKPLMLCSEFQCQENCIHQQQIPSQQQQVPVLSSPVAAAAAAAAAAQRKSSSSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKLALQGGPEGGADSPGSQYGKWPGSPNSHSNDDFEAWTAFRPRTSSNASTLSGRLSPFIDDELGDSDVHMVYPGPGSGTKMTSTLPSLSEMAGSLGHSGSENVMENLLDNLNLLSPKNPSTGGPGSGSNQSSPSSLMQASPGYSPYSSPGLSAVSQQTQQDFRKCLYGQAGMGSMSPMPMQPLPESKPSFGPGGGTMGQFNCTAGLLKELLTSDGEPGDLMPSVDTVVSQSAGGSGCMLPPYSSGRNELMGGGPTHSHTLSHPHNMHGQAPPTSVALNGRSLHPLTAIGHSSVGGRLGSGKSPMQMQYGGSGHLGGGLPPYCSMSSNGYGRGPGMMAHQQLQHLEKLPSDLDGMPIERFECDVESILHDTLMDGESLDFNFDPMNSQQGFVPHSVKTTTHSWVSG
Protein: Lectin-like transmembrane protein (Q588F6)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MSEQEVTYSTVRFHKSSGLQNQVRPEDNQGSREAGHKECSIPWHLIVIAFGILCVLLLVIVAVLVTNILQYKQEKHELQETLNCHHNCSTMQSDINAKEEMPRNMPLECSTGNDLLKSLNREQKRWYSETKSILNSSKHPEVPSVTGYSRQLLDWLLI
Protein: Probable glycosyl transferase WbpJ (Q9HZ80)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase
- LPS biosynthesis protein WbpG
- UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase
- UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate N-acetyltransferase
- Probable glycosyltransferase WbpH
- Probable NAD-dependent epimerase/dehydratase WbpK
- UDP-N-acetyl-D-glucosamine 6-dehydrogenase
- UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase
- O-antigen translocase
- Glycosyltransferase WbpL
Sequence:
MNVWYVHPYAGGPGVGRYWRPYYFSKFWNQAGHRSVIISAGYHHLLEPDEKRSGVTCVNGAEYAYVPTLRYLGNGVGRMLSMLIFTMMLLPFCLILALKRGTPDAIIYSSPHPFGVVSCWLAARLLGAKFVFEVRDIWPLSLVELGGLKADNPLVRVTGWIERFSYARADKIISLLPCAEPHMADKGLAAGKFLWVPNGVDSSDISPDSAVSSSDLVRHVQVLKEQGVFVVIYAGAHGEPNALEGLVRSAGLLRERGASIRIILVGKGECKEQLKAIAAQDASGLVEFFDQQPKETIMAVLKLASAGYISLKSEPIFRFGVSPNKLWDYMLVGLPVIFACKAGNDPVSDYDCGVSADPDAPEDITAAIFRLLLLSEDERRTMGQRGRDAVLEHYTYESLALQVLNALADGRAA
Protein: UBX domain-containing protein 2A (UBX domain protein 2A) (D3ZID8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:19474315}. Endoplasmic reticulum {ECO:0000269|PubMed:19474315}. Perikaryon {ECO:0000250|UniProtKB:Q99KJ0}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q99KJ0}. Nucleus {ECO:0000250|UniProtKB:P68543}. Cytoplasm {ECO:0000269|PubMed:19474315}. Note=Expressed at the axon initial segment. {ECO:0000250|UniProtKB:Q99KJ0}.
Interaction partners:
- Transitional endoplasmic reticulum ATPase
- NSFL1 cofactor p47
- UBX domain-containing protein 10
- UBX domain protein 8
- UBX domain-containing protein 4
- Small VCP/p97-interacting protein
- ASPSCR1 tether for SLC2A4, UBX domain containing
- UBX domain-containing protein 7
- Deubiquitinating protein VCPIP1
- Serine beta-lactamase-like protein LACTB
Sequence:
MKEVDNLDSIKEEWVCETGPPDNQPLNDNPQKDCEYFVDSLFEEAEKAGAKCLSPTEQKKQVDVNIKLWKNGFTVNDDFRSYSDGASQQFLNSIKKGELPSELQGVFDKDEVDVKVEDKKNEVCMSTKPVFQPFSGQGHRLGSATPRIVSKAKSIEVDNKSTLSAVSLNNLEPITRIQIWLANGERTVQRFNISHRVSHIKDFIEKYQGTQRSPPFALATALPFLRFLDETLTLEEADLQNAVIIQRLQKTAEPFRKL
Protein: CSD domain-containing protein (O62213)
Organism: Caenorhabditis elegans
Interaction partners:
- RNA-binding protein 42
- RNA-binding protein FUS
- ATP-dependent RNA helicase cgh-1
- Large ribosomal subunit protein mL44
- RRM domain-containing protein
Sequence:
MAEKNDVAEQPADKPVKATKVKGTVKWFNVKNGYGFINRTDTNEDIFVHQTAIINNNPNKYLRSLGDNEEVMFDIVEGSKGLEAASVTGPDGGPVQGSKYAADRDAENAARGRGGRGRGRRGGRGGIRHDSGSRDAEEGGAPRGGGRGGSRRGGGGRGGGRTNSGGEETARDTDGGERGGRGGGRRGGRGRGGRGRGGRGGQGGQSEA
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (H0Y7R3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGSSTSSLAPGPEPGPQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPGTALSNLPTPPCALPLGQYRGLLPAPVSWGPWAGQVGQLGAQGSWNTPQVPVLPVFLQPPVVSMPGPRLRIT
Protein: Cation channel sperm-associated auxiliary subunit delta (CatSper-delta) (CatSperdelta) (Transmembrane protein 146) (E9Q9F6)
Organism: Mus musculus (Mouse)
Function: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CATSPER1 stability before intraflagellar transport and/or incorporation of the CatSper complex channel into the flagellar membrane.
Subcellular location: Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:21224844, ECO:0000269|PubMed:34225353}; Single-pass type I membrane protein {ECO:0000255}. Note=Specifically located in the principal piece of sperm tail. {ECO:0000269|PubMed:21224844, ECO:0000269|PubMed:34225353}.
Interaction partners:
- Cation channel sperm-associated auxiliary subunit beta
- Cation channel sperm-associated protein 1
- Cation channel sperm-associated protein 2
- Cation channel sperm-associated auxiliary subunit gamma 2
- Cation channel sperm-associated protein 3
- Cation channel sperm-associated protein 4
- Cation channel sperm-associated auxiliary subunit epsilon
- Cation channel sperm-associated auxiliary subunit zeta
- EF-hand calcium-binding domain-containing protein 9
- Solute carrier organic anion transporter family member 6C1
Sequence:
MLVLMLAAAVATMVRAHTLCRVHTVRTGKVFKSNIQLQGDPLFYAFPNTFVLKNVCKADISVYLGQKVFLTIDNFESSLLPLTVPKSLAVGVPSITSAHFVSGSLVLFVISGKGYSYDYYENTWRKLEGISEPVSHISGDVCCFKGSFCLELSNNLFAYLRGGQIPGTNIYFSDNGGFSFQLMNTDKLSHLTGTLGGIFHLHSMSQVGVLMVENNLGTFHYMEYPLNHSMGIAFSYKNLLEVIMKPYQRGFMVLWNQKSILVSSNSGQIVEHVRLIDQKIFTDLDVEHANINIYSVASNAYELAFLVAEDHLYYGSQSYMGTYVIKLPHQPLWSTHTSIYFEDIGILQVLTPVADPHFAAYDFDKCTVNVQSSLMDEKLALQPCNVELLESTMINTMFTIDMNSKLKLSALMIPRKGENPTPLVMVSNPHALGFKANLNEFGNTFDGNSKYKLDIELKQQHHWGNSDFNFTASIKRHAISSVTVDIADKTLSCVDLKPLSTLISVGCDMTKKIVVQNKISACTMGILNPVQLQKNYTYTIEKEAYDPINHNGEAQDDLIVFYEYKDLGCPRLVYYDKPWKPVVELWKNGIVEEIMNAEYVISEINGLVTYSYSLTAATANCRSQPQNWSTFESDIENEEPFLWNRENYVSCHEDNKDNPLLWPNVEYQVLGGQTNNKIIFGQRNGIYTFHLSVVDPYYSYCNLNTIFSVYVHGALPVTKFQPLLTILLMVTTTLLTAWLAYAIPKQLRSEKGQRLLGFCYQILQLCLGVCFCTWLRGKLRQWLRPRRVKDQNRGKVRVAQKHPET
Protein: Whey acidic protein (WAP) (P01173)
Organism: Mus musculus (Mouse)
Function: Could be a protease inhibitor. May play an important role in mammary gland development and tissue remodeling.
Subcellular location: Secreted.
Interaction partners:
- Beta-casein
- Alpha-S1-casein
- Alpha-S2-casein-like A
- Alpha-lactalbumin
- Alpha-S2-casein-like B
- Amine oxidase
- WAP four-disulfide core domain protein 2
Sequence:
MRCLISLVLGLLALEVALAQNLEEQVFNSVQSMFQKASPIEGTECIICQTNEECAQNAMCCPGSCGRTRKTPVNIGVPKAGFCPWNLLQTISSTGPCPMKIECSSDRECSGNMKCCNVDCVMTCTPPVPVITLQ