wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquitin-like domain-containing protein CIP73 (CCaMK-interacting protein of approximately 73 kDa) (D5LXJ0)
Organism: Lotus japonicus (Lotus corniculatus var. japonicus)
Function: Involved in root nodulation. Required for root nodule organogenesis after infection by symbiotic rhizobia. Probably not involved in arbuscular mycorrhizal (AM) symbiosis. Acts downstream of CCAMK.
Subcellular location: Nucleus {ECO:0000269|PubMed:21209278}.
Interaction partners:
Sequence:
MGSNGTEEITSDISTGNAATTIEIKIKMLDSQTFTLRVDKQMPVPALKAQIESLTGVMSERQRLICQGKVLKDDQLLSAYHVEDGHTLHLVARHPDLTPPGSLPNHSATEPNSSTGHGYSNQVAPGVFIETFNVPVQGDGVPSEINRIVSAVLGSMGLPNFASGGEGIFVREHDSTGLGRTSDFTGNPSRPQPEQAGFRISSDSSRNSFGFPAAVSLGSLGSLQPPVIPDSLTTLLQYLSHINHEFDTIAREGGNNVQAAEAHRNEERGFVSSRLSSTPEGLSSPASLAEVLLSTRRVIIEQAGECLLQLARQLENHADIADPLSRSSTQSRALRTGVMFYNLGAYLLELGRTTMTLRLGQTPSEAVVNGGPAVFISPSGPNHIMVQPLPFQPGASFGAIPVGAAQSNSSLGGGLGSSFFPRRIDIQIRRGASTTPGTNQEEHGDTQSASVQRNTGESSVNQTTSRRPDASIAGEPGVRVVPIRTMVAAVPVLGRFQSSVNTNNEQGSQPASQQHTAPHSTAEFTLHRQSMEDSARNGTLPTPNTQQEPSSSRVVNINILSAGGPENNESERQVPSSVLQFLRALFPGGEIHVEDPSSQGTTAGVTSAATSSGAAQAPEAEPNVSEEGIFLSNLLRGIMPVISQHIGRGGDSSEDQVTRDPSTQVEIGAGTSRRQSDSESSPPNSKRQKME
Protein: Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Neuronal and epithelial glutamate transporter) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1) (P43005)
Organism: Homo sapiens (Human)
Function: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity). Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport (By similarity). Negatively regulated by ARL6IP5 (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:21123949, ECO:0000269|PubMed:26690923, ECO:0000269|PubMed:7521911, ECO:0000269|PubMed:7914198, ECO:0000269|PubMed:8857541}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P43003}. Apical cell membrane {ECO:0000269|PubMed:21123949}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P43003}. Synapse, synaptosome {ECO:0000250|UniProtKB:P51906}. Early endosome membrane {ECO:0000250|UniProtKB:P51906}. Late endosome membrane {ECO:0000250|UniProtKB:P51906}. Recycling endosome membrane {ECO:0000250|UniProtKB:P51906}.
Interaction partners:
- PRA1 family protein 3
- Excitatory amino acid transporter 4
- Sodium/potassium-transporting ATPase subunit beta-3
- Amino acid transporter heavy chain SLC3A1
- Polyadenylate-binding protein-interacting protein 2B
- Disks large-associated protein 3
- Solute carrier family 15 member 1
- Glutamate receptor ionotropic, NMDA 2B
- Zinc finger protein GLIS3
- Adenylate cyclase type 6
Sequence:
MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
Protein: Insulin-like growth factor 1 (Insulin-like growth factor I) (G8HMZ4)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MEKINSLSTQLVKCCFCDFLKVKMHTVSYIHFFYLGLCLLTLTSSAAAGPETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSRRLHHKGIVDECCFPICDLRRLEVYCAPIKPPNSARSVLGQRHTDMPKAQKEVHLKNTSRGNTGNRNYRM
Protein: Erythrocyte membrane protein 1, PfEMP1 (Q8IAK3)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MVPPVRSPRAAGPAPAPASASTTYGSVKDLLEDIGKSIQKQAKDAAEKRSNGELQGDLSKARFKDQKNTTTNPCQLNYRNHSNVRSSFENDNPCYGREEKRFSDSRSGQCTYNRIKDSKEGDNKVGACAPYRRLHICDHNLENINDYKNINNHTLLVDVCLSAKHEGEMIANKLKEYDKSNYESRICTVLARSFADIGDIVRGKDLYLGDQQEKLYLENNLKKIFAKIHENLNDKIKSNYNDSEGNYFKLREDWWTANRDQVWKAITCNAPKDANYFEYNSGKFFKFSNDQCGHNNGGAPPTNLDYVPQFVRWFEEWADDFCRIRKHKLKNIKDVCRNESKPLYCSLNGYDCTKTSWKNDFESREHYCTPCFSACSLYKIWVANQKKEFEKQKKKYEKEIPKYVSKKVKTNSTINNYYYYDFYEKLQKNEYGNIDAFLNLLKEGKYCKENLPEEEVINFTKHDEKKTFSLSNYCVVCPDCGVEYKNGRYTAKDQKYPDCRNEKYDPNNAETTDITVLYSGDVGDFSEKLQDFCNDINNGKVKNYQIWQCYYENSEINKCQMTPSSHKVPKHGYIMSFFAFFDLWVKNLLIDTINWKNELTNCINNTNVTDCKNDCNTNCKCFENWAKTKEKEWENVKTIYKNENRNTNNYYKKLNDLFKGYFFHVMYELNNEEAKWNKLMKNLRTKIDSSRKNAGNEDSEGAIKVLFDHLKDIAERCIDNNSIKPCNSHPKPTPNPCGKNNNGGKLVRVKRPAELKQQKAHIQLEKRGGESNLKGDATRGTYNLGCQGDQLDATFCNIDEKYSNRIPRKSEGPCYGKNPQRFYTGKDWTHVVQEKTSYKDVFLPPRREHMCTSNLENLNLNSKGLSNSSIASNSLLGDVLLAAKYEADDIVKKNDSDKSSICNAMKYSFADIGDIIRGKDMWDLDSGSKDMEKHLISIFEKIKENLDVIKYNSKYKDTQKFLDLRSDWWEANRHQVWRAMKCAIENDKDMKCNGIPIEDYIPQRLRWMTEWAEWYCKAQKKEYDELVKGCKGCMGNGQGCTKDSSDGECKKCTEACNTYKQKIKTWENQWKKIKGKYEKLYEQATKNGETSGTPNEKDKDVVDFLKQLLPRNSAAARNRVIRAAGSSAPGVTALTPITLYSSAAGYIHQELGKTVGCNTQKEFCKNGSGEKYAFKHPPKEYKDACSCNTRDKKSEAPVTKKEEACKIVDGILKGNDGINEISGCNPKESYPEWQCDKSKFKNGEEGACMPPRRQKLCVSGLTQGGKITTIEDIRTQFITCAAIETHFAWHKYKKDNVNAERELNSGIIPHEFKRQMYYTFGDYRDIFFGTDISTHNHIPEVSQKVITILEKENLTKSEVKQKYKNELLDDWWNEHGKEIWDGMVCALCYDTKTKEFKNEVRTQLTGPNSKYQYGTVSFGDKQNTILSKFAERPPFLRWFIEWGEEFCKKRKEQVDQLVNVCKECNVSDSVISSGNKTCNDKEKCDACKKECTQYENWLQTWKGHYNKQKERYAKVKSTSPYNNDNDVNKSTHAYEYLSKKLTNIPCTNGNTTGKCDYKCMDQRTSTDGMPASLEYPPKEINGKCDCTKALPPQEPPSTPESRGRSLNPPPDSPQPPRGPEEQEESASYSEEEEEEEEEEEENDEENDGDEEEVKTEDGGSDDEDEDEEDDEEEEENEVDVDEPQQEEVEEPPAKESAPTTQEPAVPEVKKQEVKVCDIVSKILTKDALQDACKLKYNGKYYGWKCISGATTGGLCIPPRRRKLYVTPLTKWATTAVSSEATPAPSQSESDKLREAFIQSAAIETFFLWHKYKQEKKPPSEQNAGAALVLLQGVTPQEDPQNKLKSGTIPEEFKRQMFYTLGDYADIFFGKNDILIGKTGTGSAKDEMADKESKIKEAIKKFFQNGDSQPLSGKPVTQSSDKRTALWGDFAQDIWHGMICALTYTDSGEKGELPKEDDKVKDKLWDDTKKQPKKEEYQYDKVKLDENSGDGPKTSQPPSAPSDTPTTLDSFIKRPPYFRYLEEWGQNFCKKRTEMLGKIKGDCRVEDGSKNCSGYGEDCDDQLGEDPSTVPSLKCQSCGEECRKYKKWIERKKDEFTKHSNAYGDQKAKCQAKSGGGGNGFCGTLERCSKAAEFLKTLGSCKTNNGNESVEANKTIFDNIGETFKPATNCKPCSQFKIYCKNCKSSGDDTNVGCNCKENGNGYITSDHIKNEDNFTDPVDMLVSDDNTNGNKFADLQACGGAGIFKGIRKDQWKCRNVCGYVVCKSEKGNGETVRGEKNDVKHIITIRALVTHWVEYFLDDYNKINKKLNRCMKDGEGYQCIKDCVEKWIQNKREEWKKIKELYLQEYKNNNQPDYLVKIILEELHPQTQLNEAIKPCKTFDDFKSFCGLNGAESSKKSKNSNDNDLVLCMLNKLEKKIDECKQKHQASGKNTAQCQEYPPLPDEEYENEEENDKKVEPPTFCEIKDTPEPADEDACKAAPKETAPSSEENQPETPVIKPEEEAPAPEEPPPAPPPLAPSDESILHTTIPFGVALALGSIAFLFLKKKTKSTIDLLRVINIPKSDYNIPTKLSPNRYIPYTSGKYRGKRYIYIEGDSGTDSGYTDHYSDITSSSESEYEELDINDIYVPGTPKYKTLIEVVLEPSGNNTTASGKNTPSDTQNDIQNDGIPSSKITDNEWNTLKDEFISQYLQSEQPKDVPNDYKSGDIPFNTQPNTLYFDKPEEKPFITSIHDRNLYSGEEHSYNVNMVNSMDDIPINSHNNVYSGIDLINDTLSGNQHIDIYDELLKRKENELFGTNHVKQTSIHSVAKPISDDPIHNQLELFHKWLDRHRDMCEKWENHHERLAKLKEEWENDTSTSGNTHPSDSNKTLNTDVSIQIDMDNPKTTNEFTYVDSNPNQVDDTYVDSNPDNSSMDTILEDLEKYKEPYYDVQDDIYYDVHDHDTSTVDTNAMDVPSKVQIEMDINTKLVKEKYPIGDVWDI
Protein: SSD domain-containing protein (D2N110)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MRFDCIEKRFAHAFGAYSGVVVRHPFPFFIIPILITAGLSTGLLRHEQAFMKDELELYTPTDAQARKELSQLDHLFHINDSDPFYATRRYDIRRAGYIIVTNQEEDGDILNPLVMHSAMQLWSIVQSLTVEDEDDRRINYPSICVKFPIPPEFSKALHSLFAPNMTTPEEICVSNPLVEIFKLLLVSDRSFLNRSIDEMTLSQISDAIQFDSGGMTHLLGGVTLDDDKRIAGAKAMLLPYALRHSSDDEDWVAEKWEVRLADFLLQYDSPIIRASWWTYETLAAESARDRLQLIHMLLPCFVCVSIFTIACCCVFSWRRSRPWLAIGGVISAAMAIASAVGILLLAGYGMTSVAYSMPFIVFSVGVDNVFILLSAWRSTSSTETLEHRMKETFADAAVSITVTSLTDLISFGVGCATPFPSVQMFCAYAVAAVIFTYIYQLTFFAAVMVYTNRREINNRHCIFFHKLKKDTLPEKIAAQGDRSFEKNTILAQFFRTTYSDFLLNPLVRIVILVTFCVYLGVASYGCTKVKLGLEPNDLLPENSYGKRTLMMAEKYFSDYGSSLHVWMYNLSEVDVAPRKIWNVLEKEVELYEHTEFTASSDSWLRTFLAFVKQAGLLITPENFVYILKNVFLSQPQFAKYNRDVVLTEDGEHLEASRIPVQLRHVGSANQSRAMSSLNNTMQFFRVPFPRSHMQVSLLLQFPLSSFQNLSPLYGYPSR
Protein: Minichromosome maintenance domain-containing protein 2 (MCM domain-containing protein 2) (Q4G0Z9)
Organism: Homo sapiens (Human)
Function: Plays an important role in meiotic recombination and associated DNA double-strand break repair.
Interaction partners:
- DNA replication licensing factor MCM3
- DNA replication licensing factor MCM5
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM7
- DNA helicase MCM9
- DNA replication factor Cdt1
- Cell division control protein 45 homolog
- WD repeat and HMG-box DNA-binding protein 1
- Cell division control protein 6 homolog
- Protein MCM10 homolog
Sequence:
MSNLKMKEAALIYLDRSGGLQKFIDDCKYYNDSKQSYAVYRFKILINPSDVVELDAELGNHILHQPLKAAEVFQSVCFIAVKTLSLIGQLQTETQINIVLKLTHLPPLPSYGLDLCEFPLDYTSQRFYMMQGIVIAMTTITKYTQGARFLCSDEACPLSKGFQYIRVHVPGATESATIRNDFLCNLCASSLQEDRKFRVLGDKQIVEIIATKALRAFQGYSNNQPFRFQSLTIFLRDESVNKMNIGNEYKIIGIPTCVKTSQTAVCIEANSITFCNSKVPSGISDNFRCLLSLTSSSCWKFTAILANIFASQITPPGTYNLLKLCLLMSLVQTTDRNKELEDCLDILIITSDTLLIDRLLNFSINLVPRGIRHLVSTEIFPTLSRNKYGTGAVSIQAGSALLAKGGICFIGDLASHKKDKLEQLQTVLESRSITVYIPGKKFGEDIDQQMTFPVQCSFWSFVDVDSSSRRNAQKINTLIGQMDCSLIPANLVEAFGLLINCNESSPCHPFLPTVQHTLNKAINPEGLFYAASRQFTTEDFEKLLAFAKNLNVEFSLEAERMTHGYYLASRRIRTGSVCGSKLSASALKYLVFLSEAHARLNLRNKVLKEDVLIAALLFETSLTLKYGATVFCVAPNAVFPFELYNEEYLEQRDLYLTQCQQQLEQFIATYGPGTTIFSSDE
Protein: Threonine--tRNA ligase (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Q8PRY4)
Organism: Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Function: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (Probable). Edits incorrectly charged L-seryl-tRNA(Thr) probably via its editing domain (tested with total bovine tRNA). Activates L-serine, but does not detectably transfer it to tRNA (tested with total bovine tRNA).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00184}.
Interaction partners:
Sequence:
MQLLLIHSDYIEYETKKQTPVAEKIEESLKSGRLEEALTAFTAVESVDEANPEEAIKKAVSEIEKVAAQVKTNRIMLYPYAHLSSDLSSPKVAVQVLKGMEAALSSRYEVKRAPFGWYKAFTVSCKGHPLSELSRSIRPEGAAKAEVKTETCEKEEVVSEALKAEGTARSYWRILTPDGELHEVEGFDLTPYPKLQQFVNYEISKSRAVERAPPHVELMRRLELADYEPGSDSGNMRYYPKGRLVKSLLENYVLDVATEFGAMEVETPLMYDMNHPTLKKYLDRFPARQYSIESDKRHMFLRFAACFGQFLMNHDMTISYKNLPLRMIEMTRYSFRKEQRGELVGLRRLRAFTMPDMHTLCEDMDQAVNQFKEQYDLCISVLENVGIHINDYEVAIRFTRDFYEANKDLVVNMAKTVNKPVLVEMWDTRFFYFVLKFEFNFVDALAKASALSTVQIDVENAERYDISYVNADGKLERPTVLHCSPSGAIERCIYALLEKAAMETEEGKVPMLPVWLSPTQVRIVPISEKHIAFAEEVAKKLDFRVDVDDRDLSIGKKVREAGREWVPYVVVIGDKEMEESTINVTIREESGQDKPKKVQMTPEELNARIKEETSGKPYRKLPLAKYLSARPKFL
Protein: Protein pelota homolog (Q57V39)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU362019}.
Interaction partners:
- Elongation factor 1-alpha, putative
- 40S ribosomal protein S23, putative
- 40S ribosomal protein S15, putative
- Small ribosomal subunit protein uS5
- 40S ribosomal protein S16, putative
- 60S ribosomal protein L5, putative
- 60S ribosomal protein L27a
- 60S acidic ribosomal protein P0
- 40S ribosomal protein S17, putative
- 40S ribosomal protein S33, putative
Sequence:
MRLLKKSVTAEGAVEVKLQVSTSEDLWHLYNLVLPGDQVRTNTRRKVVKETSIGSQAAEVRTITLQLQVRNTEFSPDELRVQGVNVKENECVKLGAHHTLSVHAFPPQDVVILKDEWNDVFAARLKEACDNESRADTVAVLMDSGTASVLLVTPSFMYTKAKIEVSIAKKHKNDGTARDRSIQRFFKQVLDALCMHVDFDKAKLILICSPAHVREEFKAYVEAAMAHSEAMAMRNLRKNFSKIVLIKVRDNTNDALREAFADPNIANQMESTRCRDEIKVWQDFQKTMDEDPDRCVYTPQMVYRAAMLGAVGKLMVSDVVFRSEDPTVRRFYLSLIRFVRQGGGGVSVFSSNHVTGEQLTQLGFVAAILHFPCDELDDLEVVENFIDSEEAATFIRENAAASVVV
Protein: Collectrin (B5X131)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
- Angiotensinogen
- Transporter
- Transporter
- Transporter
- Transporter
- Uncharacterized protein LOC106606019
Sequence:
MLVRILVLLYLAGAPALAQTLCQPNASNGYRVRISIKTALGNQAYEWNENEMFLFRATMAFTMRRYYKTETYNVDNIIVCNQTLRVSFWFVVTSPDNSTMLIPKADVEKAVSMSRHRINNAFLLTDRTLEFLGIPPTLAGPVNPDTPPWLIVFGVVIGAVCAGIIVLLVSSLLQKRRKDKGMMEDGQDEEDRQMKGVDNGNVLDGIYNKGFTDDNRFTTL
Protein: Contig An11c0150, genomic contig (EC 1.10.3.2) (A2QW24)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Interaction partners:
Sequence:
MHLHTILAAGWLAASAYAGVSSRSTQACAGNTPHTRGQWCDFDIHTDYYDEAPDTGVVREYWLELGNTTAAPDGVPRNVLTVNGTTPGPTLYADWGDWVRVHVYNGLENNGTSIHWHGVRQNHTNPQDGTNSITQCPTPPGGSVTYEWRATQYGTTYYHSHFALQAWEGVYGGIVINGPASSNYDVDAGVLYLMDWSHRTADQMYSTAETDGEPEMTTGLINGTNIWVKENNETVGSRFLMNVTAGQSYRLRLINGGMSNLFRFMIDDHTLTVIAADFVPIEPYNTTSLNIGVGQRYDVIVTANQAQAGSDFWMRAIPQESCAEIQNTDIKGIFHYEQPDTAVATPTTTAYNYTDSCYDEPLSSLVPVVAIDASGVGYKSHNEANVIMNSAGLYKWYMGPTTFKAEWDNPTLLQIANGNTSWTNTSHVVEVEGNGKWVIVDIEMEINVPHPIHLHGHDFFILAQGKGSYTSNTSLNTYNPPRRDTAMLPALGYLVIAFKTDNPGAWLLHCHIGWHQSEGFAMQFVESISQLEPMIDASALEKNCAAWDKYAAANRIEEDDSGI
Protein: GDP-mannose transporter (GMT) (Q9UTK8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Putative transporter C83.11
- UDP-N-acetylglucosamine transporter yea4
- Protein transport protein got1
- Dolichol-phosphate mannosyltransferase
- Uncharacterized protein C12G12.12
- UDP-galactose transporter homolog 1
- UDP-galactose transporter
- Uncharacterized protein C23A1.02c
- Uncharacterized transporter C22F8.04
- Maintenance of mitochondrial morphology protein 1
Sequence:
MDNHMLNRISKSPILPVVSYCMASILMTLTNKYVLSSPGYNMNFLLLTVQSTVCVAAIGILKRLKVINYRDFDFREAKFWFPISFLLVAMIYTASKALQFLSVPVYTIFKNLTIIIIAYGEVLWFGGHVTALTLFSFGLMVLSSIVAAWADIQSSSFASQTLNSGYLWMVLNCLTNAAFVLAMRKRIKLTNFRDFDTMFYNNLLSIPVLVICTLFTEDWSAENIAQNFPPDAKFGVLMAMAISGVSSVGISYTSAWCVRVTSSTTYSMVGALNKLPLAIAGLVFFDAPITFGSVTAILLGFISGVVYAVAKSQQQRQKDPATILPMTHNPVSASSQSMRDSLSKS
Protein: Kazachoc, isoform G (A0A0B4LGD3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- non-specific serine/threonine protein kinase
- Serine/threonine-protein kinase Wnk
- Cysteine-rich PDZ-binding protein
- Ethanolamine kinase
Sequence:
MQSNSAKDDSDEMEIIPSEHNGTVHETKNEDSGDIHRAEENQKSSIDPNLYLYDDDLETRPHISTFISSIANYENTIPAATDPDAKPAAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDADAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKEDSFLRDIYCPDGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYRKIFSFATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVIIGWPYSWRQEGRNSWKTFIQTVRTVAACHMALMVPKGINFYPESNHKIGGNIDIWWIVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMDYKETPSDNKMSLVQTIVDHHYDATKTASKVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDESTEKADGDFKSSVKPDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMVRGGGREVITIYS
Protein: Transcription factor EC (TFE-C) (rTFEC) (Q63302)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
Sequence:
MTLDHRLFSQTLKRAQPLAASCMPLAEHGPRSPDSDAGCAGNPFTNPLALGKEDGVVEWRLSGSILDVYSGEQGISPVNTGLMNASCPSILPMKKEIAETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDIRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLMLRIQELEIQARAHGLPILASLGTADFGTHITKQQTHSEKNSVGCCQQLTPSQGTSPEFYEQAVAFSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISPAVSKASSRSSLSSEDGDEL
Protein: Actin-like 6A (A0A8I6AT89)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
ILGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGVVLERDDGSTMMEIDGDKGKQGGPTYYIDTNALRVPRESMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFEHYSIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELIPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP
Protein: Small ribosomal subunit protein eS25A (40S ribosomal protein S25-A) (S31-A) (P79009)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein eL39
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS9A
- Elongation factor 3
- mRNA export factor elf1
- Large ribosomal subunit protein eL31
Sequence:
MAPKKKWSKGKVKDKAQHATVFDKSIIDRINKEVPAFKFISVSVLVDRMKINGSLARIAIRDLAERGVIQKVDQHSKQAIYTRVPAATA
Protein: Alpha-crystallin domain-containing protein 22.3 (AtAcd22.3) (Increased DNA methylation 2-like protein) (Q84K79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Methyl-CpG-binding domain-containing protein 7
- Methyl-CpG-binding domain-containing protein 5
- Protein IDA-LIKE 2
- Methyl-CpG-binding domain-containing protein 6
- Protein IDA-LIKE 3
- Protein IDA-LIKE 1
- Increased DNA methylation 1
- Calcium-binding protein CML39
Sequence:
MRSSSGLNGMRENNSFPDNTRNPQILEVTPLNSMPYIGPVTHASMSSNRMNDSVEKVGGPAMIFLPSDSSSEFSNLISQTKTGVALTGSAAMGKIGLTIGLVDIAESEDSYYFRVALPGVSRDEKEFSCEIEPDGKIMIKGATTTGEQTVCKHNQIFKMLTQNLCPPGHFTINFQLPGPVSNEEFNGNFGSDGVLEGVVKKVYYED
Protein: Myocyte-specific enhancer factor 2D (Q63943)
Organism: Mus musculus (Mouse)
Function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251, ECO:0000269|PubMed:18299387}. Note=Translocated by HDAC4 to nuclear dots. {ECO:0000250}.
Interaction partners:
- Myocyte-specific enhancer factor 2A
- Myocyte-specific enhancer factor 2C
- Nuclear factor of activated T-cells, cytoplasmic 1
- Nuclear factor of activated T-cells, cytoplasmic 2
- Nuclear factor of activated T-cells, cytoplasmic 3
- Myoblast determination protein 1
- Nuclear factor of activated T-cells, cytoplasmic 4
- Histone deacetylase 4
- Myogenin
- Histone deacetylase 5
Sequence:
MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSSVPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLPSAELSSLPAFSSPAGLALGNVTAWQQPQPPQQPQPPQPPQSQPQPPQPQPQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK
Protein: UBP1-associated protein 2A (UBP1-interacting protein 2a) (Q9LES2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus. Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs. May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus. However, unlike UBP1, UBA2A does not stimulate pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000269|PubMed:12024044, ECO:0000269|PubMed:16828085, ECO:0000269|PubMed:18278441, ECO:0000269|PubMed:18705666}. Note=Relocalizes into nuclear speckles in response to abscisic acid (ABA).
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 1
- Spc97 / Spc98 family of spindle pole body
- Ubiquitin-activating enzyme E1 2
- La-related protein 1B
Sequence:
MTKKRKLEGEESNEAEEPSQKLKQTPEEEQQLVIKNQDNQGDVEEVEYEEVEEEQEEEVEDDDDEDDGDENEDQTDGNRIEAAATSGSGNQEDDDDEPIQDLLEPFSKEQVLSLLKEAAEKHVDVANRIREVADEDPVHRKIFVHGLGWDTKTETLIEAFKQYGEIEDCKAVFDKISGKSKGYGFILYKSRSGARNALKQPQKKIGSRMTACQLASKGPVFGGAPIAAAAVSAPAQHSNSEHTQKKIYVSNVGAELDPQKLLMFFSKFGEIEEGPLGLDKYTGRPKGFCLFVYKSSESAKRALEEPHKTFEGHILHCQKAIDGPKPGKQQQHHHNPHAYNNPRYQRNDNNGYGPPGGHGHLMAGNPAGMGGPTAQVINPAIGQALTALLASQGAGLAFNPAIGQALLGSLGTAAGVNPGNGVGMPTGYGTQAMAPGTMPGYGTQPGLQGGYQTPQPGQGGTSRGQHGVGPYGTPYMGH
Protein: Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like) (Q6Y288)
Organism: Homo sapiens (Human)
Function: O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:16899492}; Single-pass type II membrane protein {ECO:0000269|PubMed:16899492}.
Interaction partners:
- GDP-fucose protein O-fucosyltransferase 2
- Spondin-1
- Properdin
- Relaxin receptor 2
- A disintegrin and metalloproteinase with thrombospondin motifs 9
- Thrombospondin-1
- ADAMTS-like protein 1
Sequence:
MRPPACWWLLAPPALLALLTCSLAFGLASEDTKKEVKQSQDLEKSGISRKNDIDLKGIVFVIQSQSNSFHAKRAEQLKKSILKQAADLTQELPSVLLLHQLAKQEGAWTILPLLPHFSVTYSRNSSWIFFCEEETRIQIPKLLETLRRYDPSKEWFLGKALHDEEATIIHHYAFSENPTVFKYPDFAAGWALSIPLVNKLTKRLKSESLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTNDVDFYCATTFHSFLPLCRKPVKKKDIFVAVKTCKKFHGDRIPIVKQTWESQASLIEYYSDYTENSIPTVDLGIPNTDRGHCGKTFAILERFLNRSQDKTAWLVIVDDDTLISISRLQHLLSCYDSGEPVFLGERYGYGLGTGGYSYITGGGGMVFSREAVRRLLASKCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQARPVDYPKDYLSHQVPISFHKHWNIDPVKVYFTWLAPSDEDKARQETQKGFREEL