wanglab/gogpt-training-data huggingface dataset:
Protein: G1 to S phase transition 1 (Q7T358)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Elongation factor 1-gamma
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2a.
- 3'-phosphoadenosine 5'-phosphosulfate synthase 1
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
- Eukaryotic peptide chain release factor subunit 1
- Eukaryotic translation termination factor 1a.
- Src-like adaptor 1a.
- Valine--tRNA ligase
- Ribosomal protein S3
Sequence:
MDAIDTAPDSWDQEDDGEAQVDVQLSKALTSLNVDAKPFVPNVHAAVFVPSFQQKGSAETVESAGPDTDANVEVAEPEAPPMENGDAEMATDDTWEQKGSEPSEAEAEPGGPARDGGQPEEDSPQEEGMEEEEEVPTPKVVPTQPNAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLVNKMDDPTVNWSLERYEECKEKLVPFLKKVGFNPRKDVHFMPCSGLNGANLKEPAENCPWYTGLPFIPHLDSLPNFNRSSDGPVRLPIVDKYKDMGTVILGKLESGSIGKAQQLVMMPNRHTVEVLSLLSDEVETDEAGPGENLKLRLKGIEEEEILPGFILCNAENLCHTGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVQITALICLVDKKTGDKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVAEKD
Protein: DNA-directed RNA polymerase II, putative (Q386T9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription initiation protein, putative
- Plastid-encoded RNA polymerase subunit alpha
- Spt4/RpoE2 zinc finger domain-containing protein
- DNA-direcetd RNA polymerase II, subunit 9, putative
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- RNA polymerase-like protein
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit, putative
- Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2
Sequence:
MSTSHGMLIYNNDITADSLLDTKDCRKIVEEVSSKMPNSSLFKLDREDHTLANLLRMRLHENPLVHIAGYRVPHPTQHRVELRVQTSSDGTGKPIPTPKEALLEAVGSCMKDLEEFEGAFLREAQSKGLDVE
Protein: Protein transport protein SEC39 (Dependent on SLY1-20 protein 3) (Q12745)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15958492}; Peripheral membrane protein {ECO:0000269|PubMed:15958492}.
Interaction partners:
- Protein transport protein TIP20
- Protein transport protein DSL1
- Protein transport protein SEC20
- Syntaxin UFE1
- Protein transport protein USE1
- Synaptobrevin homolog YKT6
- Protein SLY1
- Protein transport protein SEC22
Sequence:
MLEEQLYLLACIFASRADTRNIKKLSTRLGSQSKYLEILCVLWPELDDPKNLLFLRELEEEVQSPEGEETTDEDVIVELLESDSSLIPLIESDTTTRSNRYHELQEFISKKLNNKTLENFEEWLRERILICNEMIPETPLLYSVLWETAKSKVLSTKFIGWVEGVLKPLDHLNKRLHLIFKINEWEKMPDSELFKIIFDGVEDMQGYIGIADVIEDELAPTLSYGKKWETFITEFFNKQQFSLKSDTNYQLFIKLYYSLEKGVKDNSEASRKLQSNVVDILFHNSENLFNLSSLTHKLDELWSILSGFPDEITIEEQKTITALEMKQFMEFFIKCSTKFSFKEIFAITQEEESAQLAHFSSLCHEEFNKANEISSFLQAMYETVLDISKDDKIFTRISMDEKLYSILEILLQMNEFAYIEAIIERFDYSNNTQIYELLVKFFWHFFNNASNGLRKEPEMKKASQTLQIIQKHMSQRAGTNLTKLEVLLEISDKLSHYSINLNKSHNGARDTAFKPSNILEYRDCPLDIISNLLELNPRLYKDLPTTKSLLFGIYDSLSINREGQTGKVEVDLMVLHIDYALVNLDFGTAYELGKQVFEICQEAGQHMMKALGDEHWLTFYQMGKFVDPNWVDNEIPTEIIVLQMSILGRLLEVCPLEEVEIVTSQWSTLELELSARDLVKDKYALDGQNDNKSKVGGIAREIFHNVTNF
Protein: DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1) (Q9JHY8)
Organism: Rattus norvegicus (Rat)
Function: DNA ligase that seals nicks in double-stranded during DNA repair. Also involved in DNA replication and DNA recombination.
Subcellular location: Nucleus.
Interaction partners:
- Flap endonuclease 1
- DNA repair protein XRCC1
- DNA polymerase beta
- Proliferating cell nuclear antigen
- DNA ligase
- Exonuclease 1
- X-ray repair cross-complementing protein 5
- DNA helicase
- X-ray repair cross-complementing protein 6
- E3 ubiquitin-protein ligase UHRF1
Sequence:
MQRSIMSFFQPTTTEGKAKKPEKEIPSSIREKEPPPKVALKERNRAVPESDSPVKRPGRKVAQVLSSEGEDEDEAPGTPQVQKPVSDSKQSSPPSPDSCPENSPVFNCSPSMDISPSGFPKRRTARKQLPKRTIQDTLEEPNEDKAKAVKKRKKEDPQTPPESLTEAEEVNQKEEQVEDQPTVPPEPTESPESVTLTKTENIPMCKAGVKQKPQEEEQSKPPARGAKPLSSFFTPRKPAVKTEVKQEESDTPRKEETKGAPDPTNYNPSKSNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPTDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPSPPLTVSGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRYSEARFIARSLSGRLRLGLAEQSVLAALAQAGSLTPPGQEFPTVVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLESLPEHCKLSPGVPLKPMLAHPTRGVREVLKRFEEVDFTCEYKYYGQRAQIHVLEGGEVKIFSRNQEDNSGKYPDIISRIPKIKHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLARQPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGRGKRPGRYGGFLLAAYDEESEELAAICKLGTGFSDEELEEHHQNMQALLLPTPRPYVRIDGAVAPNHWLDPSIVWEVKCADLTLSPIYRAARGMVDKEKGISLRFPRFIRVREDKQPEQATTSDQVASLYRKQSQIQNQQSSDLDSDVEDY
Protein: Serine peptidase inhibitor, Kazal type 5 (Q148R4)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Kallikrein c
- Filaggrin
- Desmoglein-1-alpha
- Kallikrein-7
Sequence:
MKTATVPMLLTLAFYLTQDAAGEKGNQDPCMKFQAQMKNGTLTCPKGNNSSQSLNDIIFQSECILCKRALEQGAPTKIMNVKVLSRANRATDPAKLNCESFKQRRKDGDFICPSDTSSVCGTDGKTYRSRCELCAENAKSQNHVDVKSEGECGSSHLETDMCSDFRAYVQDGRLGCTRESDPILGPDGRTHGNRCAMCAELFLKEAKENATRNRESRIRRDAEKELCKEFENQVRNGRLFCTRESDPIRGPDGKMHGNKCALCAEIFMRQFTEEKGKAEKNQKDAEERAKAKMEIQKRCSEFQDRARNGTLFCTRENDPIRGLDGKTHGNLCSMCQAFFKTEAEEKKAEAGSRNRRGSEESETYAKLCDEYRKARKNGQLYCTRENAPIRGPDGKIHGNTCSMCQAFFIQEDKARAKVKREAAKEMCSEFRNQARNGMLMCTRENDPVVGPDGKRHSNKCAMCASVFLLEEEEKKKDDKTEKVDAGKAKKEAVQELCRKYHTQLRNGPLRCTRRNNPIEGLDGKMYKNACFMCWAFFQQEAKKSGAGFRPKVKREVKVDCSEYLALSKRGEIFCTRENDPVRGPDGKTHGNKCAMCKAVFKKENEERKRKEGENQRITSGESSSGGNPKAKDECAQYRESMKHGQLSCTRESDPVRGVDGEHYNNKCVMCKELLQKEMEETNKNSASRSNGTGSATGKDVCDQFRSQMKNGKLLCTRESDPTRGPDGAMHGNKCAMCKERLEKEAAEKKKKEDEEKRNTETNKSDKEDKCHEYRSMQLDGRLICTRENDPVRDADGKMHVNKCAMCQMMFEREANERKMREENSRSQPTNEAKDQCGEVHNSVEDAKPRPARSSLPSIRGISKDECSEFQNLMKNEKLTCPETDDPVRGADGTFYQNKCHMCRDVLKNEAMKRSGLQEKSSDIRSTKEGDPEFSSSSRDSDMCKNYRILPRMGYLCPKNLNPVCGDDGQTYSNPCMLCHENLMRQTNTRIHKQGACEESSNLKTVSTGTPASEKMMQ
Protein: Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cytoplasmic tRNA adenylyltransferase 1) (Q94480)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03053}.
Interaction partners:
- Cytoplasmic tRNA 2-thiolation protein 2
- Elongator complex protein 3
- Adenylyltransferase and sulfurtransferase MOCS3
- DNA replication licensing factor mcm5
- Molybdopterin synthase catalytic subunit
- Molybdenum cofactor biosynthesis protein 1
- Molybdopterin synthase sulfur carrier subunit
- Iron-sulfur cluster assembly 2 homolog, mitochondrial
- Iron-sulfur cluster assembly 1 homolog, mitochondrial
Sequence:
MENTATKKKSKLCEVCNVSRPVLKRPKTGEMICKECFYTVFEDEIHHTIISNNLFKRGDRVAIGASGGKDSTVLAEIMTLLNKKYDYGLDLFLLSIDEGITGYRDDSLETVKRNQEQYQIPLKILSYKELYNWTMDDIVKEIGLKGNCTFCGVFRRQALDRGAVMLKANKIVTGHNADDIAETVLMNLLRGDIPRLQRCVNIITGSEGALPRSKPFKYTYQKEIVMYAYFKKLDYFSTECIYAPNAYRGHARDFLKDLEAVRPSIIIDIIHSAENFHFREENKMPVQRNCIQCGYICSNDICMACDLLKNLNSGLAKVKLSINLKRGKDNNNNSNNNDNNNTLKLESTSAATTTTTTVSN
Protein: Calcium-transporting ATPase (EC 7.2.2.10) (G5EC26)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|RuleBase:RU361146}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361146}. Sarcoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004326}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004326}.
Interaction partners:
Sequence:
MIETLTSEQAASHEVVPCTHQLRTNLEEGLTTAEATRRRQYHGYNEFDVGEEEPIYKKYLEQFQNPLILLLLASAFVSIVMKQYDDAISITVAVVIVVTVGFVQEYRSEKTLEQLTKLVPPTCHVLRDGKEAMMLARELVPGDIVLLNTGDRIPSDLRIAESFSLQIDESSLTGETEPKHKETRSVPAASATGSDVEHLTCIAFMGTLVCAGRGRGIVISTAANSQFGEVVKMMMGEESPKTPLQKSMDDLGKQLSIYSFGVIAVIFLIGMFQGRNVVDMFTIGVSLAVAAIPEGLPIVVAVTLAIGVMRMAKRRAVVKKMPAVETLGCVTVICSDKTGTLTKNEMTAQAIATPEGKLAEITGIGYSAEGGVVQYQGEQVHQWTHPEFARIIEAGLVCNNATIEADKLIGQPTEGAIVVLAKKAQLEGVRSEYKRLREMPFSSDTKWMGVQCADAHGQNVYFIKGALDRVLDQCGTYYSSDNQRKQCDQYSRQHILEIGKELGQKGLRVLGLARGESMQSLMFLGMIGMMDPPRPGAADAISIVKASGVDVKLITGDAMETAQSIGQSLGILSSSDSCLSGQQVDQMSDHDLELVIRQVTVFYRASPRHKLKIVKALQALGEVVAMTGDGVNDAVALKKADIGVAMGVCGTDVCKEAADMILCDDDFSTMTAAIEEGKAIYHNITNFVRFQLSTKLNSTQTNYKL
Protein: Dye-decolorizing peroxidase Tfu_3078 (DyP) (EC 1.11.1.19) (Peroxidase Tfu_3078) (Q47KB1)
Organism: Thermobifida fusca (strain YX)
Function: Peroxidase that is able to convert a large number of compounds, but its physiological substrate is not known. Shows high reactivity towards anthraquinone dyes (e.g. Reactive Blue 19) and a modest activity towards standard peroxidase substrates (such as guaiacol and 2,6-dimethoxyphenol) and azo dyes (e.g. Reactive Blue 5). Is also able to oxidize aromatic sulfides enantioselectively, resulting in the corresponding (R)-sulfoxides, but with a poor efficiency. Does not display catalase activity.
Subcellular location: Secreted {ECO:0000305|PubMed:19967355}.
Interaction partners:
- Copper chaperone PCu
- Similar to Cu resistance protein CopC
- GST C-terminal domain-containing protein
- Similar to Uncharacterized protein SCO1/SenC/PrrC involved in biogenesis of respiratory and photosynthetic systems
Sequence:
MTEPDTERKGSSRRGFLAGLGAAALTGAGIGMAAGEVLRPLLPDSDPAASPEAEQRLRMAAQRADATAAPQPGISGPAPAFVHVIALDLAEEARKNPDTARDSAAAALRSWTELAARLHEESPHDIAEGAASAGLLPASLMVTVGIGGSLLSAIDAEDRRPDALADLPEFSTDDLHPRWCGGDFMLQVGAEDPMVLTAAVEELVAAAADATAVRWSLRGFRRTAAAARDPDATPRNLMGQIDGTANPAQDHPLFDRTITARPADNPAHAWMDGGSYLVVRRIRMLLTEWRKLDVAARERVIGRRLDTGAPLGSRNETDPVVLSARDEEGEPLIPENAHVRLASPENNLGARMFRRGYSYDQGWRDDGVRDAGLLFMAWQGDPATGFIPVQRSLADQGDALNRYIRHEGSALFAVPAAREGRYLGQDLIEG
Protein: Glutathione reductase (EC 1.8.1.7) (V9HW90)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU365016}.
Interaction partners:
Sequence:
MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
Protein: Nuclear receptor corepressor 1 (J3KS29)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XTQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGRPGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTT
Protein: Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin) (Q13444)
Organism: Homo sapiens (Human)
Function: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:12243749}; Single-pass type I membrane protein {ECO:0000269|PubMed:12243749}. Cell junction, adherens junction {ECO:0000269|PubMed:12243749}. Cell projection, cilium, flagellum {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Note=The majority of the protein is localized in a perinuclear compartment which may correspond to the trans-Golgi network or the late endosome. The pro-protein is the major detectable form on the cell surface, whereas the majority of the protein in the cell is processed (By similarity). {ECO:0000250}.
Interaction partners:
- Sorting nexin-9
- SH3 and PX domain-containing protein 2A
- Growth factor receptor-bound protein 2
- SH3 and PX domain-containing protein 2B
- Proto-oncogene tyrosine-protein kinase Src
- Cadherin-1
- Endophilin-A1
- Mitotic spindle assembly checkpoint protein MAD2B
- Tyrosine-protein kinase HCK
- SH2/SH3 adapter protein NCK1
Sequence:
MRLALLWALGLLGAGSPLPSWPLPNIGGTEEQQAESEKAPREPLEPQVLQDDLPISLKKVLQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQGRVRGYAGSWVSICTCSGLRGLVVLTPERSYTLEQGPGDLQGPPIISRIQDLHLPGHTCALSWRESVHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIVADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPLNVRVALVGLEAWTQRDLVEISPNPAVTLENFLHWRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLPGLNFSNCSRRALEKALLDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTCQLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTGRTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLGSDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLGAQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTTQLKATSSLTTGLLLSLLVLLVLVMLGASYWYRARLHQRLCQLKGPTCQYRAAQSGPSERPGPPQRALLARGTKQASALSFPAPPSRPLPPDPVSKRLQAELADRPNPPTRPLPADPVVRSPKSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPTVSSLYL
Protein: Uso1_p115_head domain-containing protein (G5EGG0)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
- Putative syntaxin-5
- BET1 homolog
- Golgi SNAP receptor complex member 1
- PDZ GRASP-type domain-containing protein
- Golgi SNAP receptor complex member 2 homolog memb-1
- YKT6
- RAB family
- Golgi SNAP receptor complex member 2
- Golgin subfamily A conserved domain-containing protein
- Conserved oligomeric Golgi complex subunit 6
Sequence:
MFAYSTSSITGSTLSVRSFSSDTTISNAFFNLPQSNFRQRLQAKKRSPKRVSKRAPLRTHPPIPRQMSLFRNFFGGGQQDEDEDNGAEYVETLVERAETCTAPEDRRDALRGLKGVAKKYRLAVGTMGMNAFIDVLETDRMNTEAMTIVLDTMAIVLSTDDDSSESDELGERLAEVMIKRKGFISSVLCAVEQFDIGVRRTAIQLISNLLRHRGTEVQKAVMEHPQGIAKLVDVIHDNREIIRNEAILMICELSRANSQVQQLLAYDNIFLDLLNIIETEPLDSIVIEDCMFVMLNLLRKHAMNQQIFREDQFVARLGKILHTFLYGNEETEDIEVTEWAKQRTANVIFLLQIIRTLVSPDNTSENTHAAQKVLNQTKILEELCRVLLSEIGASVEILTESIIVVAEAIRGNYTNQELFANTVLDNGEDVPRTSLVVLLISMTAEKQPYKLRCAVFYCFLSYLFDNEFGKARVIETLLPQSHNSSSSLTTGALILQAISSAESVQAWFGCVTLMHCLYDVDHLSEQLLRVNLTVVTEDPPLTLLNHVCQLLVSTGNRRPQTRAGLLMLLGTWLQNCPAAVSDFMAKDEHIQYLTTNLVDECGEGSESEQQVLRGLMAFVLLSCLKNLQSKEARSSMEILIQRRVGKELILSALEGLSRTEQFVRAAQKQQPTNELFLDFHFVKLFKSLEGTLAKQLKPNGEFNGTSNDSIIQSYKELIKRQDGDIAQLKQDNKRMSLEIEKLNAEVQNKQMEREVENLRVRLEESEAFKTQNEVLNSQLVESQRLTQQWYAEAERYKQWAQQWQAYQLAQLPNGVETGLAQLQQQVNELEQQLGFGYQAFEQQSQTMLHYTSENANLKDRLAKTEAALAEANYKIEQLNLKPISNGIVVEHEPQADSEEFSKLKQEQEELLMLLADQHNKMSAYRRLLRNLKQPVTDDEDE
Protein: SXP/RAL-2 family protein Ani s 5 (allergen Ani s 5) (A1IKL2)
Organism: Anisakis simplex (Herring worm)
Subcellular location: Secreted {ECO:0000269|PubMed:18618144}.
Interaction partners:
Sequence:
MKTLIVAALFCTIGMALADDTPPPPPFLAGAPQDVVKAFFELLKKDETKTDPEIEKDLDAWVDTLGGDYKAKFETFKKEMKAKEAELAKAHEEAVAKMTPEAKKADAELSKIAEDDSLNGIQKAQKIQAIYKTLPQSVKDELEKGIGPAVPQ
Protein: Na(+)/H(+)-K(+) antiporter GerN (Q9KI10)
Organism: Bacillus cereus
Function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Can also use potassium as a coupling ion, without completely replacing H(+). This Na(+)/H(+)-K(+) antiport is much more rapid than Na(+)/H(+) antiport. Can also extrude lithium. Important for the inosine-dependent germination of spores.
Subcellular location: Membrane {ECO:0000269|PubMed:11566988}; Multi-pass membrane protein {ECO:0000269|PubMed:11566988}.
Interaction partners:
Sequence:
MEFEFFFQIALILLSTKLAGDLSVRLGQPSVLGKLIVGIVIGPAVLGWIENSELLTQLSNVGVILLMFMAGLETDLEELNANRNSSLAVALGGIILPFVGGYVSGLVMGMEQGNAVFLGLLLCATSVSISVQTLRDLGKMKTRESTTMLGAAVFDDILVVILLAFAMSFLGTDDVNLTMVILKKVVFFASIILIGWKGVPAIMRWLSPLRVSESIVSAALIICFSFAYFGELLGIAGIIGAFAAGIAISQTNYKHEVEKKVEPIAYAMFVPVFFVSIGMNITFDGIGNQIWFILALTVIAVLTKLIGCGFGARMTGFDAKSSAIIGAGMVSRGEVALIIAGTGLSSGLLAQDYFTAIVIVVILTTMITPPMLKYTFGAKDKAMKASK
Protein: Synaptosomal-associated protein 25-B (SNAP-B) (Synaptosome-associated protein 25.2) (SNAP-25.2) (Q6PC54)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
Subcellular location: Synapse, synaptosome {ECO:0000250|UniProtKB:P36978, ECO:0000250|UniProtKB:P60880}. Cell membrane {ECO:0000250|UniProtKB:P60881}. Note=Complexed with macromolecular elements of the nerve terminal. {ECO:0000250|UniProtKB:P36978, ECO:0000250|UniProtKB:P60880}.
Interaction partners:
- Syntaxin 1A
- Vesicle-associated membrane protein 2
- VAMP/synaptobrevin
- Vesicle-associated membrane protein 3
- Syntaxin 1B
- Synaptotagmin
- Uncharacterized protein LOC436805
- Syntaxin 4
- Vesicle-associated membrane protein 7
- N-ethylmaleimide-sensitive factor attachment protein, beta a.
Sequence:
MADESDMRNELNDMQARADQLGDESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGNLCGLCPCPCNKLKGGGQSWGNNQDGVVSSQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVGSIIGNLRHMALDMGNEIDTQNRQIDRIMDMADSNKTRIDEANQRATKMLGSG
Protein: Resistance to inhibitors of cholinesterase protein 3 (Q22472)
Organism: Caenorhabditis elegans
Function: Required for maturation and cell surface expression of acetylcholine receptors.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:11867529}; Multi-pass membrane protein {ECO:0000305|PubMed:11867529}.
Interaction partners:
- Protein unc-50
- Acetylcholine receptor subunit alpha-type acr-16
- Acetylcholine receptor subunit alpha-type deg-3
- Acetylcholine receptor subunit alpha-type unc-63
- Acetylcholine receptor subunit alpha-type unc-38
- Acetylcholine receptor subunit beta-type unc-29
- AcetylCholine Receptor
- Acetylcholine receptor subunit beta-type lev-1
- AcetylCholine Receptor
- CUB domain-containing protein
Sequence:
MPKTERRRDRDRDRDRERRNRRKRDDSYDDYDEEGGISGWKLGLVFGVIVVCFAMLYPTLFHPMLMGFLGRSPPSSPSINQQRPPIHPAMGGGSGQRHPGGGADVHPAMRMAQAQAESQSGGSKGMFTWMLPVYTIGVVLFLLYTLFKSKGKKSKRKKRNYFDSEDDDDESESETKYGGKFGKKKLEGLQKRLRETESAMSKILEQLESVQAGANPVDLDAADKRSEQLEEDPSVKEAVGLTETNEQYIKDLEVALKEFQSLSKEYDKAKMKKLKRKDSSSDEDEEDEEENSSELSEIEEEEEEVKPVKKSKSSSQSVGKRKNRPKSTSEEEDEGEEESRKVAEDAEEEGIDIDSEIREHAEKEKKDKNVRRRRPKKT
Protein: Filamin A interacting protein 1 (A0A075B6G6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKRYSRALRPSVNGRRMVDVPVTSTGVQTDAVSGEAAEEETPAVFIRKSFQEENHIMSNLRQVGLKKPVERSSVLDRYPPAANELTMRKSWIPWMRKRENGPSITQEKGPRTNSSPGHPGEVVLSPKQGQPLHIRVTPDHENSTATLEITSPTSEEFFSSTTVIPTLGNQKPRITIIPSPNVMPQKQKSGDTTLGPERAMSPVTITTFSREKTPESGRGAFADRPTSPIQIMTVSTSAAPAEIAVSPESQEMPMGRTILKVTPEKQTVPTPVRKYNSNANIITTEDNKIHIHLGSQFKRSPGTSGEGVSPVITVRPVNVTAEKEVSTGTVLRSPRNHLSSRPGASKVTSTITITPVTTSSARGTQSVSGQDGSSQRPTPTRIPMSKGMKAGKPVVAAPGAGNLTKFEPRAETQSMKIELKKSAASSTTSLGGGKG
Protein: Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1) (Q08AG7)
Organism: Homo sapiens (Human)
Function: Required for gamma-tubulin complex recruitment to the centrosome.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20360068}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:20360068}.
Interaction partners:
- Gamma-tubulin complex component 3
- Gamma-tubulin complex component 6
- Gamma-tubulin complex component 4
- Gamma-tubulin complex component 5
- Mitotic-spindle organizing protein 2A
- Mitotic spindle organizing protein 2B
- Gamma-tubulin complex component 2
- Tubulin gamma-1 chain
- Nucleoside diphosphate kinase homolog 7
- Protein NEDD1
Sequence:
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEALSSVIKELRKATEALKAAENMTS
Protein: Protein FAM136A (Q9CR98)
Organism: Mus musculus (Mouse)
Interaction partners:
- Dystrobrevin alpha
Sequence:
MAEVQQLRVQEAVDAMVKSVERENIRKMQGLMFRCSANCCEDTQASMQQVHQCIERCHAPLAQAQALVTSELERFQDRLARCTMHCNDKAKDSMDAGTKELQVKRQLDSCVTKCVDDHMHLIPTMTKKMKESLSSIGK
Protein: Sodium-dependent lysophosphatidylcholine symporter 1-B (NLS1-B) (Sodium-dependent LPC symporter 1-B) (Major facilitator superfamily domain-containing protein 2A-B) (Q6DEJ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9DA75}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9DA75}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Major facilitator superfamily domain-containing 13A
- Major facilitator superfamily domain-containing 11.
- Major facilitator superfamily domain-containing protein 6-like
- Major facilitator superfamily domain-containing 9.
- Major facilitator superfamily domain-containing protein 6-A
- Putative transporter SVOPL
- SV2-related protein a.
- Major facilitator superfamily domain-containing 10.
- Protein spinster homolog 3
- Major facilitator superfamily domain-containing protein 3
Sequence:
MAKGEGAEQYTNTSLLQKPSPDEVKLAKHETKSRLSVCSKLCYAIGGAPYQITGCAIGFFLQIYLLDVALLDPFYASIILFVGRAWDAVTDPTVGFLVSRTPWTRFGRMMPWIVLSTPFAVLCYFLIWYVPSVDQGKVVWYLIFYCCFQTLQTCFHVPYSALTMFISTEQKERDSATAYRMTVEVLGTLIGTAIQGQIVGMANAPCISTEIDLNSTGLEVAPDVNITDPHVSLQDLRNAYMIASGVICAIYVVCAVVLFLGVKEQKDTCRVRTEPMSFFQGICMVMGHGPYAKLVMGFLFTSLAFMLLEGNFALFCIYNLGFRNDFQNVLLVIMLSATLAIPFWQWFLTKFGKKTAVYIGTTSVVPFLISVVLVPSSLAVTYIASFAAGVSVAAAFLLPWSMLPDVVDDFKVQNPESQGHEAIFYSFYVFFTKFASGVSLGVSTLSLDFAGYVTRGCTQPGEVKLTLKILVSAAPIVLIIIGLLIFISYPINEEKRQGNRKLLNEQRENEMDSETDSTELNVV