wanglab/gogpt-training-data huggingface dataset:
Protein: Nanos-type domain-containing protein (O18218)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSGQQFQQHSQQQQQRAPTVYNNNNKKNGGSAANSNQNNNNPHHTSTTDSVPNSTANVSSAISFEYSEPPGNTTRTTPDSGLGTDDQKGTPQQTRAPPGFHRAAYHRNSGQQQFSQMRPQPPHTGPPNGMTYYGGTVGAPGYQQQQPPPQEGYDQQQQFGGGSDGGQYQRGPPGGYRQYQQMESGGPPSGYADDNNGGNNNFVIHGPNDNFDGRPQYNPQAGPPPQNQQQMMNSGNYEIDQYRGQGPPPGNTYQQQGHSGQAQYYAGPVIQQRPPPPHNAQSYGQYRGPQGPQGQIIQMMPHNPQNQQQQQQHPMLYPMVYVPVPAPRVFRQEPAGGASSLEKDGGNARKSKRNSQNEDDGQQHQHQNEQQPQQGYHQQDFVSNPLWNQMPVGYAPPGNFTQPQQQHQQMDQQQAVQMQHQMQQMQPYGMPQGGPPPPHAAASMMNHPHQQNHPHMNAQMTQQQHPGQYLPQQYMQMVPPPHHQMQQMQQQGRRPGGVEPLMGGPPYQMSGQINQMGGPIRGGFGMQQQQPMGYFNSGRGGNAGSGRGRGGSRGHGYQHSRQNSNQSYNSSQSYPQNRGNFDSSSQYQSDSQQVDESVTQLTNRIEHLQPVSSRAGSPSKQILQLVESKDDQTSTENSESPSRSSTPKHRKKTPKKDFKVDQEASIEATKTEISEENPKTDDIQSKDDVTSKSELHCYRCEHYQLPAEEVSSHNIRKDNGDLWCEHMKKIKCGHCEATGEQGHHPLICPKKKEEERVAKSRESSQKPIDPQEISDDQDDTVPDVPDQIVEQDNQSHKSRHNSENRSGGRGYGQNYSHSYGGNSTGSYRGRSSGGSGGSGRGGGRGGYSRGHGGGSGGGQRGNYQFPE
Protein: Small ribosomal subunit protein uS2 (30S ribosomal protein S2) (P0A7V0)
Organism: Escherichia coli (strain K12)
Function: Required for ribosomal protein S1 to bind to the 30S subunit.
Interaction partners:
- Large ribosomal subunit protein uL16
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein uL3
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein bL25
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein bL17
- Small ribosomal subunit protein uS3
Sequence:
MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
Protein: Protein B4 (Histone H1-like protein) (Linker histone B4) (P15308)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00837, ECO:0000269|PubMed:3060404}. Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837, ECO:0000269|PubMed:3060404}.
Interaction partners:
Sequence:
MAPKKAVAAPEGGNKENAAVKGSSKVKVKRKSIKLVKTQSHPPTLSMVVEVLKKNTERKGTSVQAIRTRILSAHPTVDPLRLKFLLRTALNKGLEKGILIRPLNSSATGATGRFKLAKPVKTTKAGKENVASENVDPNAEQETQKKAPKKEKKAKTEKEPKGEKTKAVAKKAKEDSDEKPKVAKSKKDKEAKEVDKANKEAKEVDKANKEAKEVDKAPAKKPKAKTEAAKAEGGGKAKKEPPKAKAKDVKAQKDSTDEGAPVKAGKKGKKVTN
Protein: Profilin (allergen Citr l 2.0101) (Q5XWE1)
Organism: Citrullus lanatus (Watermelon) (Citrullus vulgaris)
Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity). Has a high affinity for poly-proline.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P35081}.
Interaction partners:
Sequence:
MSWQAYVDDHLMCEIEGNHLTSAAIIGQDGSVWAKSENFPQLKPEEITGILNDFNEPGTLAPTGLYIGGSKYMVIQGEPGAVIRGKKGPGGVTVKKTALALVIGIYDEPMTPGQCNMIVERLGDYLIEQGL
Protein: Double-stranded RNA-specific adenosine deaminase (A0A3B3IRQ9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQTPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLRSQGLQRGFQHPSPRGRSLPQRGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Protein: Longitudinals lacking protein-like (Lola-like protein) (Protein Batman) (Q7KRI2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required, together with Trl, for maintaining the repressed state of target genes including homeotic genes Scr and Ubx. May also be involved in the activation of homeotic genes. Binds to a DNA Polycomb response element (PRE) at the bithorax complex. Also binds to polytene chromosomes at several hundred sites, many of which are shared with Trl and ph-p. Required during embryonic development.
Subcellular location: Nucleus {ECO:0000269|PubMed:12556479}.
Interaction partners:
- Protein argonaute-1
- Transcription activator GAGA
- Protein Gawky
- Transcriptional coactivator yorkie
- Centrosomal and chromosomal factor
- Polyhomeotic-proximal chromatin protein
Sequence:
MMSSDQQFFLKWNDFQTNMVTSFRHLRDEKSFTDVTLACEGQTCKAHKMVLSACSPYFKALLEENPSKHPIIILKDVSYIHLQAILEFMYAGEVNVSQEQLPAFLKTADRLKVKGLAETPSSIKREG
Protein: Transcriptional regulatory protein sds3 (Clr6 histone deacetylase complex I subunit Sds3) (Q9UTB6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the clr6 histone deacetylase complex I responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Histone deacetylase clr6
- Transcriptional regulatory protein rxt2
- Chromatin modification-related protein png2
- Paired amphipathic helix protein pst3
- RbAp48-related WD40 repeat-containing protein prw1
- Transcriptional regulatory protein rxt3
- Paired amphipathic helix protein pst1
- Paired amphipathic helix protein pst2
- Putative histone deacetylase complex subunit cti6
- Chromatin modification-related protein eaf3
Sequence:
MDVLSRVFDNEKEELDPLLNNPLTASEFRAKKAELEAELESIRNGTCKTLLDLADELRRSRDEELEIAERWRTFLVNRAQEEYEVEMKAAKEEYEYRCKTLKEMVLSHLNEKKRKIYEAKDMFDIGSESSTLLLHDASSQFIDRRKLRHRRNAGNQQNTQQLPSLNFFDDYLLFPTDETAVIPQSVKNAVRNSVNSVKPTSAEASLFSPLLSMANANPTNGRERDPRASERAERDREKAVEKGLSGATEEDIQSDLQLLKKELAKKK
Protein: BTB/POZ domain and ankyrin repeat-containing protein NPR1 (OsNPR1) (NPR1 homolog 1) (OsNH1) (Q9FDY4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Key positive factor of disease resistance. Plays an essential role in benzothiadiazole (BTH)-induced resistance to the blast fungus disease caused by Magnaporthe oryzae. Involved in defense response against the bacterial blight disease caused by Xanthomonas oryzae pv. oryzae (Xoo). Over-expression of NPR1/NH1 confers disease resistance to Xoo, but also enhances herbivore susceptibility. Functions as a transcriptional coactivator of TGA2.1 and LG2 in vitro. Involved in defense response against herbivore. Plants silencing NPR1/NH1 have increased herbivore-induced trypsin proteinase inhibitors and volatiles, which reduces the performance of the striped stem borer (SSB) Chilo suppressalis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17309686}. Nucleus {ECO:0000269|PubMed:17309686}. Nucleus, nuclear body {ECO:0000250|UniProtKB:P93002}. Note=Accumulation as monomer in nucleus after induction by salicylic acid (SA) treatment or after pathogen infection. {ECO:0000269|PubMed:17309686}.
Interaction partners:
- Transcription factor TGAL6
- BTB/POZ domain and ankyrin repeat-containing protein NPR3
- Transcription factor TGAL10
- Transcription factor TGA2.2
- BTB/POZ domain and ankyrin repeat-containing protein NPR2
- Transcription factor TGA2.3
- Transcription factor TGA2.1
- Os12g0138800 protein
- Transcription factor TGAL1
- Os05g0492000 protein
Sequence:
MEPPTSHVTNAFSDSDSASVEEGGADADADVEALRRLSDNLAAAFRSPEDFAFLADARIAVPGGGGGGGDLLVHRCVLSARSPFLRGVFARRAAAAAGGGGEDGGERLELRELLGGGGEEVEVGYEALRLVLDYLYSGRVGDLPKAACLCVDEDCAHVGCHPAVAFMAQVLFAASTFQVAELTNLFQRRLLDVLDKVEVDNLLLILSVANLCNKSCMKLLERCLDMVVRSNLDMITLEKSLPPDVIKQIIDARLSLGLISPENKGFPNKHVRRIHRALDSDDVELVRMLLTEGQTNLDDAFALHYAVEHCDSKITTELLDLALADVNHRNPRGYTVLHIAARRREPKIIVSLLTKGARPADVTFDGRKAVQISKRLTKQGDYFGVTEEGKPSPKDRLCIEILEQAERRDPQLGEASVSLAMAGESLRGRLLYLENRVALARIMFPMEARVAMDIAQVDGTLEFNLGSGANPPPERQRTTVDLNESPFIMKEEHLARMTALSKTVELGKRFFPRCSNVLDKIMDDETDPVSLGRDTSAEKRKRFHDLQDVLQKAFHEDKEENDRSGLSSSSSSTSIGAIRPRR
Protein: Exosome component 2 (A3KFL2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG
Protein: T-cell acute lymphocytic leukemia protein 2 (TAL-2) (Class A basic helix-loop-helix protein 19) (bHLHa19) (Q16559)
Organism: Homo sapiens (Human)
Interaction partners:
- Rhombotin-2
- Rhombotin-1
- Transcription factor E2-alpha
- Transcription factor 4
Sequence:
MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDRTLLENYQVPSPGPSHHIP
Protein: Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit) (P48591)
Organism: Drosophila melanogaster (Fruit fly)
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Interaction partners:
- Ribonucleoside-diphosphate reductase subunit M2
- DNA replication licensing factor Mcm5
- Thymidylate kinase
- Thymidylate synthase
- DNA replication licensing factor MCM4
- Proliferating cell nuclear antigen
- DNA replication licensing factor Mcm2
- DNA replication licensing factor Mcm7
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- DNA replication licensing factor Mcm6
Sequence:
MLKNKSMKTSKLYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFVTPEKTYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNKKQGAVSMNGQNGTAEGSPQKYEEDRERKMADMVCSLENKDACMSCGS
Protein: DNA replication regulator SLD3 (P53135)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for loading and maintenance of stable association of CDC45 with chromatin during initiation and elongation of DNA replication. Also involved in temporal regulation of origin firing. Required for the association of PSF1 with origins.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA replication regulator DPB11
- Cell division control protein 45
- DNA replication complex GINS protein PSF1
- DNA replication licensing factor MCM2
- DNA replication complex GINS protein PSF2
- Mitochondrial morphogenesis protein SLD7
- DNA replication regulator SLD2
- DNA replication complex GINS protein SLD5
- DNA replication complex GINS protein PSF3
- DNA replication licensing factor MCM4
Sequence:
METWEVIASVKEATKGLDLSLDHPLIIKSEDVPSNILQLLQQKNRRQLKHICMKSRKEYFLLEEYGPGFWVKWPYNYFNGYSLPERRTEVVTTVERERAKRETLKTWDELKFKELLHLWSEEPKGSCKLEKDKDLKLDMNPPDMKGESKINDYYSDPKEYIESKYYDALFSIHTPLAYFVKSNLVRLKNTCRTKYGSDSYKIAYQAMLQKFLLSIVQFKDRHDNRLLLEPFSSPIADEKRKNCLTKFVIQDENKNSSTIADLCVVLKSREIKLQILLLLEIIGLNDLDWNFRDFEKKYKLKLKKRSLNLTKKGLVRRRSKKKTSEKDKGIERITTSLDYCEQLDLYLDRACILDILLSSETPNPDAIEASNGTIQEHKKNILDKSKEASLVGFINYVLIPYFNKKVPHAVEFIIQKLKGPSMRPKRALKKVNDSTNVSSPNTVETYNRLSTSQRASRSSIINSVPSSPALRRVDANLFSRKSIASPTPELLNSRTNSNLNEFLESETRSLKRPSQLGRTKSDLTMNHLQKRQFSVSDLSTTRVPNSSTITLKTPFSHSTINAYKTMNNSFRRVGKRKDINETIRLHERVDSEENVQVQATPAVKKRTVTPNKKAQLQSIIESPLNFKDDDTHEGRKNTSNITSTPTNKPPENSSKRRVRRRLFAPEST
Protein: Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)] (Q02955)
Organism: Rattus norvegicus (Rat)
Function: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein. Cell membrane {ECO:0000305}. Secreted {ECO:0000250}.
Interaction partners:
- Interleukin-1 beta
- Interleukin-1 alpha
- Myeloid differentiation primary response protein MyD88
- Interleukin-1 receptor accessory protein
- Interleukin-1 receptor antagonist protein
- TNF receptor-associated factor 6
- Interleukin-1 receptor-associated kinase 1
- Interleukin-1 receptor type 2
- Interleukin-1 receptor-associated kinase 4
- Interleukin-1
Sequence:
MENMKVLLGFICLIVPLLSLETDKCTEYPNEVISFSSVNEIDIRSCPLTPNEMHGGTIIWYKNDSKTPISADKDSRIHQQNEHLWFVPAKMEDSGYYYCIMRNSTYCLKTKITMSVLENDPGLCYNTQASFIQRLHVAGDGSLVCPYLDFFKDENNELPKVQWYKNCKPLPLDDGNFFGFKNKLMVMNVAEEHRGNYTCRTSYTYQGKQYPVTRVITFITIDDSKRDRPVIMSPRNETMEADPGSTIQLICNVTGQFTDLVYWKWNGSEIEWDDPILAEDYQFLEHPSAKRKYTLITTLNVSEVKSQFYRYPFICFVKNTHILETAHVRLVYPVPDFKNYLIGGFAIFTATAVFCACIYKVFKVDIVLWYRDSCSDFLPRKASDGRTYDAYVLYPKTYGEGSFAYLDTFVFKLLPEVLEGQFGYKLFICGRDDYVGEDTIEVTNENVKRSRRLIIILVRDMGSFSCLGQSSEEQIAIYDALIREGIKIILLELEKIQDYEKMPESIQFIKQKHGAICWSGDFKERPQSAKTRFWKNLRYQMPAQRRSPLSKHHLLTLDPVLDTKEKLQAETHLPLG
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 1 (Protein acetyltransferase BLOC1S1) (A0A8I6AE76)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MPLYGDHPELREPRWGEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKGQLQSAPS
Protein: G-protein coupled receptor family C group 5 member B (A-69G12.1) (Retinoic acid-induced gene 2 protein) (RAIG-2) (Q9NZH0)
Organism: Homo sapiens (Human)
Function: Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10945465}; Multi-pass membrane protein {ECO:0000269|PubMed:10945465}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:10945465}; Multi-pass membrane protein {ECO:0000269|PubMed:10945465}. Note=Localized in the plasma membrane and perinuclear vesicles.
Interaction partners:
Sequence:
MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW
Protein: Zinc finger CCCH domain-containing protein 61 (AtC3H61) (Tandem CCCH Zinc Finger protein 5) (AtTZF5) (Q9FKW2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, Stress granule {ECO:0000269|PubMed:26978070}. Cytoplasm, P-body {ECO:0000269|PubMed:26978070}.
Interaction partners:
- Cysteine proteinase RD21A
- Protein MARD1
- Zinc finger CCCH domain-containing protein 14
- tRNA-dihydrouridine
- Zinc finger CCCH domain-containing protein 17
- Uncharacterized protein PHLOEM PROTEIN 2-LIKE A4
- Zinc finger CCCH domain-containing protein 15
Sequence:
MDVEHHKSGHISRPTVDIPPRKLLSSAKSPSSVSSPLRDYKEQKDYCYDSDSEDPYAGDHFRMYEFKIRRCTRSRSHDWTDCPFSHPGEKARRRDPRRFHYTGEVCPEFSRHGDCSRGDECGFAHGVFECWLHPSRYRTEACKDGKHCKRKVCFFAHSPRQLRVLPPSPENHISGGCGGSPSSSPASVLSNKNNRCCLFCSHSPTSTLLNLSRSPSSSPPLSPADKADAFSRLSRRRTAVLNELISSLDSLSLTEALAASSSSPVTMPISTATMIASSNLSSNHHHHRLPPWLDVGDRDLQLQQSSPLRFALSPSSTPSYLHGQLQPPPSSFFGDEFTPRGGRLSDFSVAAAAAAQARDKNSFEVGSSGDLDLGWVNDLLT
Protein: Nuclear hormone receptor family member nhr-86 (Q965W2)
Organism: Caenorhabditis elegans
Function: Orphan nuclear receptor.
Subcellular location: Nucleus {ECO:0000269|PubMed:20461074}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 15
- Nuclear hormone receptor family member nhr-79
Sequence:
MEPLDNTSLEESQFRPEKKEKSTCSICREDGDGYHFGAEACRACAAFFRRSVSLDKTYLCRGNNDCEITANIRCMCRSCRFAKCLEVGMNPAGVQQRRDTIGKREIKPDSTDLMQLLGSVGDGYPPTTSAQSALVEDLHPSFNDRMPILMKMRVNYRKMDNARLVIHRKDGQSLFKEKTPKAVNYKEACAQSIREVSLVADWVAWCFDDFVTLPMDQKKVLFRNFYTPFSVLEGAFLCHINDTSNALILPSGDYIDTNNLKSFFNIPDEEQPMTDDEIEKFCRMFKPSFELNRRGLVLPMMAEKIDVFEFFALCTFVFWDFGLDEQTDDCMMIGKSVKDRVMKELAFYLRCAKRLEEPSLRVASLLTLLPALQRCVRRFQEDIEITNVFNVYAPPKDFYDLVNGKFC
Protein: Transcription initiation factor TFIID subunit 9B (Neuronal cell death-related protein 7) (DN-7) (Transcription initiation factor TFIID subunit 9-like) (Transcription-associated factor TAFII31L) (Q9HBM6)
Organism: Homo sapiens (Human)
Function: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription initiation factor TFIID subunit 7
- Transcription initiation factor TFIID subunit 6
- TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 11
- Transcription initiation factor TFIID subunit 1
- TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 4
- Transcriptional adapter 3
Sequence:
MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTSQRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKRKHEDDDDNDIM
Protein: Xanthine permease XanP (P0AGM9)
Organism: Escherichia coli (strain K12)
Function: Specific, proton motive force-dependent high-affinity transporter for xanthine.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:16096267}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Guanine/hypoxanthine permease GhxP
- Adenine permease AdeP
- Phosphoribosylformylglycinamidine synthase
- Guanine/hypoxanthine permease GhxQ
- Phosphoribosylglycinamide formyltransferase
- Formate-dependent phosphoribosylglycinamide formyltransferase
- N5-carboxyaminoimidazole ribonucleotide mutase
- Adenine permease AdeQ
- N5-carboxyaminoimidazole ribonucleotide synthase
- Phosphoribosylformylglycinamidine cyclo-ligase
Sequence:
MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQGTSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPLVSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLMLVFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGITAIVLNLIFPPEKQ
Protein: Bcl-2-like protein 15 (Bcl2-L-15) (Bcl-2 family kin) (Bfk) (Q5TBC7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRMLGDQFNGELEASAKNVIAETIKGQTGAILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLLEYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES
Protein: CHROMATIN STRUCTURE MODULATOR (Q8SRG7)
Organism: Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Interaction partners:
- TFIIS N-terminal domain-containing protein
- DNA-directed RNA polymerase II subunit RPB1
- TRANSCRIPTION ELONGATION FACTOR SII
- Chromatin elongation factor SPT5
- RNA polymerase II subunit A C-terminal domain phosphatase
- FACT complex subunit POB3
- FACT complex subunit
- Transcription elongation factor SPT4
- DNA-DIRECTED RNA POLYMERASE II THIRD CHAIN
- Tetratricopeptide repeat protein
Sequence:
MGDSSSEEVINISRREHQVARKRVLEDLFEEDEREISEESISSIDYGDRDSLFFEIFGTGEEYRYVLESDPHEVAEEAGRCDEPTPESKTVDLDKVYEYAANNMRTRTESLKKIIELVGRGYTIHFALLHSGIEDVGIEEGYEVVDIFDEYREFVDLKEKMRRRYGNDKLLQDIEGIQGLKWYSAYKKHLDKDLSLPDELLSAEDFCENIKAKKKIHEPRNSSFLSDFANEDKLIQRISLHPVFRSALYTVFRNHGIRSEKNGLDVRDDVMKRDLVDFYLSDISSEDPWNRYRERIIRSSAEKAAKEAIVPLVLKETDLREMKRRVFVEAVDRIVNGSIGIKGDGTHVCGVTREKKYLKAVTVNFEGDLVDYITVKEEEKDELLRFIEKFDPCCVAVSGSTTSIRYLMKDLSPWNPVYVESRLAHTKAEDTYSFCCNIARIIQCPEIEYSDMLEKGIVYIQQQILPRNVMVETIRKGILTAISIVGVDVNYLLNNRRKEGLLSLIPTSSSLKSSLSDLRCVMKLEDLKDLCESEVEYDNLVTYIRVHPRVLSRVSGSEILDATPVHPKNYDVVRKLCTDLCNEEGVDEKNLDPVKKALSNAKELLKTSRPKILECGDPLTIDVYKTLVDGDRPIYSGLPDHLVFKELTGCDESLIGKVVEGRISKCGNTYYLLDSNATPAAIYIRKNRGQQELFLNQLVTVRIEYMNDFLLSYTASIAVSEQKKPNHSRFMTHPLFKDLNSEQSEEYLKDHSSSILLRRSRKDCSPVVVLKVSDGIYIHMKIQEAEKYYYKGNSYDDLDEFISRVAKKMLTNFKNIKNHKYYFENEEKLLDYLNQGGSYIRYGFCLSRKYPGKLCMLYRDGRNHKEYITVDEHLVYEGRNFASLDEFVRYRKSL
Protein: Proteasome assembly chaperone 2 (Alpha-1-proteinase inhibitor-degradation deficient protein 66) (Proteasome biogenesis-associated protein 2) (P36040)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in 20S proteasome assembly. Required for maximal proteasome activity. Affects the chymotrypsin-like activity of the proteasome. Can be degraded by the proteasome. Involved in the endoplasmic reticulum-associated degradation (ERAD).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17634286}.
Interaction partners:
- Proteasome chaperone 1
- Proteasome maturation factor UMP1
- Proteasome subunit alpha type-6
- Proteasome subunit alpha type-5
- Proteasome subunit beta type-4
- Proteasome subunit beta type-7
- Proteasome subunit alpha type-3
- Probable proteasome subunit alpha type-7
- Proteasome subunit alpha type-1
- Proteasome subunit beta type-2
Sequence:
MSCLVLPLVSVGNIPQLSIDWLLNSQANEWEYLEALDSKYLVEFVGPLDRPEDGSDSLYKDADMKYSSALEVFYNKKRGLFAIQQRTPLVSVNYLNNFIVEIILPFLSKYNISEICIWDSLYAMEDENGVIVRPQEVYSLGEFYFDDEAELLSNLHLNDQESMVNNWLHFTPTSFQDKISVDQPIFKILFQILNASQRPKALRSIKYCSCLANEGDNSLDSQQFLQWIISQKVIKNAPPIVKFVRPISWQGAYGMADARDKFVDLYN
Protein: 40S ribosomal protein S19 (C0H5C2)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- 40S ribosomal protein S11, putative
- 40S ribosomal protein S28e, putative
- 60S ribosomal protein L29
- Small ribosomal subunit protein eS12
- 60S ribosomal protein L3
- 40S ribosomal protein S15
- 60S ribosomal protein L27
- Small ribosomal subunit protein eS30
- Eukaryotic translation initiation factor 4C
- 40S ribosomal protein S23, putative
Sequence:
MEDANKPKKRTFRTFQYRGVDLDKLLDLSQDELIKLFKARQRRKFQRGISKKAKSLLKKIRKSKKNCEPGEKPNPVPTHLRNMTIIPEMVGSIVAVHNGKQYTNVEIKPEMIGYYLGEFSITYKHTRHGKPGIGATHSSRFIPLK