wanglab/gogpt-training-data huggingface dataset:
Protein: Protein HUA2 (Q12134)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May have a role in actin patch assembly.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Actin-binding protein
- Transmembrane 9 superfamily member 2
- F-actin capping regulator BSP1
Sequence:
MQQTKFGKMYLDHDSVVEYSEDEIVEADRITLGYKKRLSMIENQMRHLLEDFSLDVQQIEPILADLQKYYDAFLQLLQKRNKSLQCKRSTHQPVPSPMNSQTSTNAKVNLSGKLMKFQLNSVQKFDEENILRILQNKIEFEHYFQIDKGKKQKVLLLAVYQCLNGPTRLHKVLNIEGIIHNNSIRTILGKQVSSSKWTVFLYDVKLVLLAHRQDVPNLETSKMIVRYGDLFPCALYFKDHTAY
Protein: At2g23280 (MYB family transcription factor) (MYB transcription factor) (Myb domain protein 70) (O22179)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit
Sequence:
MSGSTRKEMDRIKGPWSPEEDDLLQSLVQKHGPRNWSLISKSIPGRSGKSCRLRWCNQLSPEVEHRGFTAEEDDTIILAHARFGNKWATIARLLNGRTDNAIKNHWNSTLKRKCSGGGGGGEEGQSCDFGGNGGYDGNLTDEKPLKRRASGGGGVVVVTALSPTGSDVSEQSQSSGSVLPVSSSCHVFKPTARAGGVVIESSSPEEEEKDPMTCLRLSLPWVNESTTPPELFPVKREEEEEKEREISGLGGDFMTVVQEMIKTEVRSYMADLQLGNGGGAGGGASSCMVQGTNGRNVGFREFIGLGRIE
Protein: G-box-binding factor 3 (bZIP transcription factor 55) (AtbZIP55) (P42776)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter. G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:8672884}.
Interaction partners:
- Rho GTPase-activating protein 2
- Basic leucine-zipper 75
- Basic leucine zipper 8
- Choline transporter-like protein
- ABSCISIC ACID-INSENSITIVE 5-like protein 8
Sequence:
MGNSSEEPKPPTKSDKPSSPPVDQTNVHVYPDWAAMQAYYGPRVAMPPYYNSAMAASGHPPPPYMWNPQHMMSPYGAPYAAVYPHGGGVYAHPGIPMGSLPQGQKDPPLTTPGTLLSIDTPTKSTGNTDNGLMKKLKEFDGLAMSLGNGNPENGADEHKRSRNSSETDGSTDGSDGNTTGADEPKLKRSREGTPTKDGKQLVQASSFHSVSPSSGDTGVKLIQGSGAILSPGVSANSNPFMSQSLAMVPPETWLQNERELKRERRKQSNRESARRSRLRKQAETEELARKVEALTAENMALRSELNQLNEKSDKLRGANATLLDKLKCSEPEKRVPANMLSRVKNSGAGDKNKNQGDNDSNSTSKLHQLLDTKPRAKAVAAG
Protein: LPS-assembly protein LptD (Organic solvent tolerance protein) (P31554)
Organism: Escherichia coli (strain K12)
Function: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Contributes to n-hexane resistance.
Subcellular location: Cell outer membrane {ECO:0000255|HAMAP-Rule:MF_01411, ECO:0000269|PubMed:12207697, ECO:0000269|PubMed:12724388, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:20446753}.
Interaction partners:
- Lipopolysaccharide export system protein LptA
- Lipopolysaccharide export system protein LptC
- Lipopolysaccharide export system permease protein LptF
- LPS-assembly lipoprotein LptE
- Lipopolysaccharide export system ATP-binding protein LptB
- Lipopolysaccharide export system permease protein LptG
- Outer membrane protein assembly factor BamA
- Chaperone SurA
- Outer membrane protein assembly factor BamD
- Outer membrane protein assembly factor BamE
Sequence:
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
Protein: MutS protein homolog 5 (hMSH5) (O43196)
Organism: Homo sapiens (Human)
Function: Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis (By similarity).
Interaction partners:
- MutS protein homolog 4
- DNA mismatch repair protein Mlh3
- DNA mismatch repair protein Mlh1
- Probable ATP-dependent DNA helicase HFM1
- Mismatch repair endonuclease PMS2
- Holliday junction recognition protein
- PMS1 protein homolog 1
- DNA repair protein RAD51 homolog 1
- Meiotic recombination protein SPO11
- Protein SPO16 homolog
Sequence:
MASLGANPRRTPQGPRPGAASSGFPSPAPVPGPREAEEEEVEEEEELAEIHLCVLWNSGYLGIAYYDTSDSTIHFMPDAPDHESLKLLQRVLDEINPQSVVTSAKQDENMTRFLGKLASQEHREPKRPEIIFLPSVDFGLEISKQRLLSGNYSFIPDAMTATEKILFLSSIIPFDCLLTVRALGGLLKFLGRRRIGVELEDYNVSVPILGFKKFMLTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQEFSDDLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLLKKNQMENCQTLVDKFMKLDLEDPNLDLNVFMSQEVLPAATSIL
Protein: MAP-homologous protein 1 (P43638)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential for the formation and/or stabilization of microtubules. Binds to microtubules in vitro.
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic microtubules and mitotic spindles.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-2
- DUB-associated factor 1
Sequence:
MDSKDTQKLLKEHRIPCIDVGWLVRPSASTSKSSRPGKSESKANSVAPDIQMDTARPPVFETSVDSSSSILSSNDKGRRHSVAASLLMDNQRANAGSTSVPTNIPPPRGRSKSVVETNLSNVEADSGHHHHHRHHHHTEDAPAPKKVGFFKSLFGHRKKDQEQQEKERERKERSPSPTHVDRGAAIRRERTATISAESPPPLQYNAPPSYNDTVVPLTRSKTESEVYYENHPQSYYHGRMRTYHSPEEGKVDGTSPADDHNYGGSRPDPRLMDFLRYYKSKDYKLAAFKEGNFIKSSASPTTKKNRRASFSLHNDKPQPAKSLAHQKFDAKGRPIPPHPDAPKLPSAFRKKHPSNASIVDTVDSNSDVSSSAQNNNQTPSSHKFGAFLRKVTSYGNNNNNSTNASSLSANVNNPDTSSTSLWSSSSMEFDPSKITTVPGLENIRPLKHVSFATNTYFNDPPQQICSKNPRKGEVEVKPNGSVVIHRLTPQERKKIMESTSLGVVVGGTGQLKLLNPEEDDANAKSKEEMAPQKQNEVEAHDEEDNNSQRRNIVMAAAEAAAEARAKEAPNELKRIVTNNEEEVTVSKTASHLTIDKPMISRRGASTSSLASMVSSDTNGTNADDEGEILPPPSLKIPHDIVYTRCCHLREILPIPATLKQLKKGSTDPIPILQLRNPRPSMVEIWSFSDFLSIAPVLCLSLDGVQLTVQMLRIILSSLVYKQHFQKLSLRNTPLDEEGWKVLCYFVSKAKSLHSIDLTMVPSIKTNVQKPSKSSLKSKILRMQCNLENRSDMNWDLLTASIALMGGLEEIVISGAKMNSAQFKNFILVACIATERLGLAYNGLSKSQCDDLAKWMVQSKVTGLDVGFNDLNGKLSSFTDAVLGKIQKANEKNVFKFLSLNGTNLRVNEHDTFENNEVLKLISVLCYLENLKFLDISNNPAIFPHCVPTLIDFLPVFVNLVRLHIDYNNLSSTSVVMLAEILPMCSRLNYFSMLGTELDLASSKALAEAVRKSSSLMTLDVDYVYMPENIKEKISLYALRNIQGELKRVNSDDKDIKDSQFSSLQDQLSLLLTEKADNSEHYNKMVENFMAKIALARIKISKVVHDLFDLKLNGQLNLEGKEALIRLCFIEASLERGCDLLKQRHNNTLKSPEAVSKSRKGGNQAQPNSESCQRMLLSSSILQNSDHIALMPFGSAIVEKSSPDAEDAVEFREGDDSNVNHEDVPANDQQFRDEVDIKNKYSIIKRELEHEKLVGGGDLPVDKEILNRAAQSLDSDQIKEFLLKNDVSTILGVIDELHSQGYHLHHIFKKQGNQEETAFRTKDEQQSSQSNDSSANASPTTDPISTGSNTSRTNDNAHIPPTDAPGFDKFMNNAEENAIDAAYDDVLDKIQDARNSSTK
Protein: Nuclear receptor coactivator 4 (E9PZ59)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MITRMLELKGLFLHPFSWTLGLGTVSRMNTSLEQSGCYSNRETLLRCSDARRELELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLNEQVDLIYQ
Protein: PH-sensitive chloride channel 1, isoform I (M9NFY2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTETQTEVAAVVAIATDAGAETETETEAEAQKEPATGPEHLKAAAQVLLTIRQARQENNKHSSSQVAETHKDEGEDALARQGSIVDTAAGRIGIDIAATTIQVAERHEDGQHWQQHNVRRRRRQPDPAAHPASITKLSAISLHFHALAALAKTLQKHEDLSPVQDRQPLAYRAWQEHPYAETQMPATMSAAIIANVGATAAATSAAAFQYLGQHYKHYSQSISFYAASSVLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLEKKRYDKRLLPPVNGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALHHHDSIWTPDTYFIMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLRVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARSMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHYKGFS
Protein: Javelin-like, isoform F (A0A0B4K6H8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPTTKTQTQTTTTCSEEEEAAIIRENCDTPMATPANATTANTTTAAPITTTTTTVNTRRQEEAAAVASTPSVTKTATTTNILAAAAGCHKPLFFSRRFQDKRNFSSLPLFVYATSPSTHAHSADGVGVAKEAAAFCHKNEGFEPATHGISKTDGSCISHHSQSNGNGIEGVNGGGIVGHHLGGVLRTTDLASGAMECLPMSSAAHHPHLMAGASAVGAVSASPTATVVVGATYPHHLHHHHLSHHTPYSNSYGSHHIHSEQTKSLQELQHEVGALLEFRDLVIETFPDLKHKMASMSATPSTPTSSVGAIGGSHSVGGGSSSLATSRREWEPGIRMKRKQSHKEPSTSSAAAAPSSGAEASSSSLTRSRSNSHSGKKEPKSGENNNGSVVQDSGFSTETSSSKEGHSASSTNGAMTVAIAANRLSCAESDDELLNLLDVIHRKSNRLREEVEHLQSYERQHGDAQKTGGEGQGASKEGMTAQQFREQVERLNREDIKQLRKERDRLLDKLAEMEAETLTGRIKAAKMSDQVEELVGVKKDLEEQLKLAMAQKLELSSRVQQLQQQQQSKSSSSGSQSDYSSQRNFLSSATTVLSNGSRPSSNVISNNTFQPVVLDQPAQEAFHQSPGSDIPLRKQQQQSLGRLDGIVSTPGTRNSKCRLTDSKRFAAILLETNVLELQRHLLTLTVQNQVLAQKLESSSKSKTLLAKRLDKNSEEFEHLRYQLEEKNIELEGTKAQLRLVESRLQASNSTSNSYLHSSQHDYETNRSSASTTLMLSRRGVSDSVDSTSTAMPAPPVTQISTPSMKAMVPLAMDELQQHSSSTESAHEHENQGLQTPNSTSSPLSKTIINASPCPVGSSTPSNIAARVMSISVGGVSPFEAMTPPPRQNAFRKFGSASKPSKIPLPGSKAAAYFSGKPPTGRPSTAGRSPPSANNSSSTSYGSKSSLSRSTGNLQSLRRAETSASNHSLSTNTSRSSTSSSIPLATTPYSSGSTGNRSQPTAATTPSPRVLQNSPLPKLKRDTISSRVRHLDSLSRAQQTPEGLKGTTTNSTSIAAQLSSTLRKDLQLSGNGTGAPYNQHHLNHRRSGHSPASNSSGSGVSRRYSSASTGGSGGRAIGRDQGEPTTPTSSYGGDSDSGKVRTLKSTFLGWFK
Protein: Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9) (P62079)
Organism: Homo sapiens (Human)
Function: Regulates ADAM10 maturation and trafficking to the cell surface. Promotes ADAM10-mediated cleavage of CD44.
Subcellular location: Cell membrane {ECO:0000269|PubMed:26686862, ECO:0000269|PubMed:31792032}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Disintegrin and metalloproteinase domain-containing protein 10
- Glutamate-rich protein 3
- Tetraspanin-15
Sequence:
MSGKHYKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW
Protein: Transaldolase A (EC 2.2.1.2) (P0A867)
Organism: Escherichia coli (strain K12)
Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Transketolase 2
- Transketolase 1
- Glucose-6-phosphate isomerase
- Fructose-bisphosphate aldolase class 1
- Triosephosphate isomerase
- Fructose-bisphosphate aldolase class 2
- Fructose-1,6-bisphosphatase 1 class 2
- ATP-dependent 6-phosphofructokinase isozyme 2
- ATP-dependent 6-phosphofructokinase isozyme 1
- Fructose-1,6-bisphosphatase class 1
Sequence:
MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
Protein: 5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein) (Q9CRB3)
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Subcellular location: Peroxisome {ECO:0000305}.
Interaction partners:
- Uricase
- 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
- Retinol-binding protein 4
Sequence:
MATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS
Protein: Toxin RelE (EC 3.1.-.-) (Putative endoribonuclease RelE) (O50461)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Toxic component of a type II toxin-antitoxin (TA) system. Has RNase activity (By similarity). Overexpression in M.tuberculosis or M.smegmatis inhibits colony formation in a bacteriostatic rather than bacteriocidal fashion. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB (shown only for M.smegmatis).
Interaction partners:
- Antitoxin RelB
- Antitoxin RelF
- Antitoxin RelJ
- Toxin RelK
- Probable endoribonuclease HigB1
- Possible cytochrome C-type biogenesis protein CcdA
- Probable endoribonuclease MazF2
- Endoribonuclease MazF3
- Probable endoribonuclease MazF5
Sequence:
MSDDHPYHVAITATAARDLQRLPEKIAAACVEFVFGPLLNNPHRLGKPLRNDLEGLHSARRGDYRVVYAIDDGHHRVEIIHIARRSASYRMNPCRPR
Protein: Sulfate transporter (Diastrophic dysplasia protein homolog) (Solute carrier family 26 member 2) (O70531)
Organism: Rattus norvegicus (Rat)
Function: Sulfate transporter. May play a role in endochondral bone formation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:9575183}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:20369363}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Solute carrier family 13 member 1
- Solute carrier family 13 member 2
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- Cystic fibrosis transmembrane conductance regulator
Sequence:
MSSENKEQHNLSPRDLPEEAYGFPPELPLGAQRGSSTDLRQFEPSDRRRAFRRIHMELHEKPDTNIRQLVMRKLQKSCQCNATKIRNRIFDFFPVLRWLPKYDLKKNILGDMMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASIIYFLFGTSRHISVGIFGILCLMIGEVVDRELHKACPDIDTTSSSIAMFSNGCVVVNHTLDGLCDKSCYAIKIGSTVTFMAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSNGVGSVITTWIHIFRNIHKTNICDLITSLLCLLVLVPTKELNEYFKSKLPAPIPTELIVVVAATLASHFGKLNENYNSSIAGQIPTGFMPPQAPDWSLIPNVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTSLVLLLVLLLIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQMPKISLLGLEEESEIFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKKTLNPVLVKAAWKKAAKRKLKEETVTFHGDPDEVSMQLSHDPLELHTVVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPSVRDSLAKGEYCKKEEENLLFYSLSEAVAFAEESQKEKGVCVVNGLSLSGD
Protein: Hepatic nuclear factor 4alpha (Q5ILH0)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MEMADYSAALDPAYTTLEFENMQVLAMGSDTSPSEAANLNTSNSIGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFNRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINVLLQAEVLAQQISSPVLVMNGDIRGKKIANIADVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGVAKRSMVFKDVLLLGNDHIVPRNCPELVEVRVAIRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPSKIKRMRYQVQVSLEDYINDRQYDSRGRFGELLLLLPVLQSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSSSETPHAHHPLHPHLIQENLGTNVIVANTMPPQMHNGQMSTPETPQPSPPAGSGPEQYKLLPGAIATVAKQPTSIPQPAITKQEVI
Protein: Mitochondrial fission regulator 2 (DUF729 domain-containing protein 1) (Q8VED8)
Organism: Mus musculus (Mouse)
Function: May play a role in mitochondrial aerobic respiration essentially in the testis. Can also promote mitochondrial fission.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:20568109}. Note=Associated with membranes.
Interaction partners:
Sequence:
MPRDGTNEQRFLELPSPMSFILNILRNVLEYFGVPVDQDLLICQNKNCGSARSIVRIIGRRLPLKPCRRPHFELIPHVNSTESDDYELRVPSFADVLCVANDEEASCLRFRHSLWQKKEERKIAPFYPSKLTWDPSSPGLRQNKTETDDLPVNEAAIKKIAALEDELTFLRSQIAAIVAMQDLRESRETGFIDLSDEQVPPSSATTGLSVEPDHAPSVVLPPPPPPPPPPQFSLQPPSSLPMQPGSANTHDIDSLATEMERQLSGVKKTDDSHHSKSQRLRDVPNMLDVLKDVNKVRLRPVERSPGGRPVQKRKRRSSEWDPVSLISNALKQKFAFQDDSFDRENSSWECSPFSSPETSRF
Protein: Peroxisomal membrane protein 11D (Peroxin-11D) (AtPEX11d) (O80845)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in peroxisomal proliferation. Promotes peroxisomal duplication, aggregation or elongation without fission.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:17220199, ECO:0000269|PubMed:18539750, ECO:0000269|PubMed:20179140}; Multi-pass membrane protein {ECO:0000269|PubMed:17220199, ECO:0000269|PubMed:18539750, ECO:0000269|PubMed:20179140}.
Interaction partners:
- Mitochondrial fission 1 protein B
- Peroxisomal membrane protein PEX14
- Peroxisomal membrane protein 11B
- Mitochondrial fission 1 protein A
- Peroxisome biogenesis protein 3-2
- Peroxisome biogenesis protein 19-2
- Peroxisome biogenesis protein 19-1
- Peroxisome biogenesis protein 16
- Peroxisome biogenesis protein 12
- Dynamin-like protein ARC5
Sequence:
MGTTLDVSRAELALVVMYLNKAEARDKLCRAIQYGSKFLSGGQPGTAQNVDKSTSLARKVFRLFKFVNDLHGLISPVPKGTPLPLVLLGKSKNALLSTFLFLDQIVWLGRSGIYKNKERAELLGRISLFCWMGSSVCTTLVEVGEMGRLSSSMKKIEKGLKNGNKYQDEDYRAKLKKSNERSLALIKSAMDIVVAAGLLQLAPTKITPRVTGAFGFITSIISCYQLLPTRPKIKTP
Protein: Bromodomain and extraterminal domain protein 9 (F4K6Q7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTERNGGFPGDYCFEAPGGDYDEGSDSPRVSEGSNCSKRKVGETFGVSKMVLPLSGLSSSDRKELIRRLRQELEQIRVFQKNFELSRTVALTSSSASGLTRVKSFGMSRCSTGPGKTVNPISAASKPTPVTTAVMLLMKQCEALLKRLMSHQYGWVFNTPVDVVKLNILDYFNVIEHPMDLGTVKNKLTSGTYSCPSEFAADVRLTFSNAMTYNPPGNDVYVMADTLRKFFEVRWKTLEKKLSGTKVHTEPSNLDAHKEKHIVIPVPMAKKRKTTAVDCENVVDPAKRVMTDEDRLKLGKDLESLTEFPAQLINFLRDHNSNEGGIGDDEIEIDINDLSDHALFQLRDLLDEHLREIQNKKSSVEPCEIELLHGSVPGNSSMQHCDGSELDDEVVDIGENEHPTSSISPVTIEKDLVLGNSNGNSLGSVSGDPKMSSLPRASKGLGTIDLEPMLDGATSASPTRGLASVGGLDQLESASPEKISSVEADCQQDGNSAQNEKQLPPEKSYRAAILKNRFADIILKAREKPLNQNDTRDPEKLQREREELELQKKKEKARLQAEAKAAEEARRKAEAQAAAEAAAEAKRKLELEREAARQALMEMEQSVELNENAKFLEDLELLKTVDTDHLTNTIEEEDGPDVGLRSFSFGGSNPLEQLGLFMKQDEDEEEADPLTSPAPEIDIEEGEID
Protein: Calcitonin (P70160)
Organism: Mus musculus (Mouse)
Function: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Subcellular location: Secreted.
Interaction partners:
- Calcitonin receptor
- Calcitonin gene-related peptide type 1 receptor
- Receptor activity-modifying protein 2
- Receptor activity-modifying protein 1
- Guanine nucleotide-binding protein G
- Troponin T, cardiac muscle
- Receptor activity-modifying protein 3
- Guanine nucleotide-binding protein G
- Calcitonin gene-related peptide 2
- Protachykinin-1
Sequence:
MGFLKFSPFLVVSILLLYQACSLQAVPLRSILESSPGMATLSEEEVRLLAALVQDYMQMKARELEQEEEQEAEGSSLDSPRSKRCGNLSTCMLGTYTQDLNKFHTFPQTSIGVEAPGKKRDVAKDLETNHQSHFGN
Protein: Major immediate early protein (PE-38) (P23801)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: Plays some regulatory role in both viral DNA replication and transcriptional transactivation.
Subcellular location: Host nucleus {ECO:0000269|PubMed:10400766, ECO:0000269|PubMed:11262179, ECO:0000269|PubMed:7636971}.
Interaction partners:
Sequence:
MPRDTNNRHRSTPYERPTLEDLRRQLQDNLDSINRRDRMQEEQEENLRYQVRRRQRQNQLRSIQMEQQRMMAELNNEPVINFKFECSVCLETYSQQSNDTCPFLIPTTCDHGFCFKCVINLQSNAMNIPHSTVCCPLCNTQVKMWRSLKPNAVVTCKFYKKTQERVPPVQQYKNIIKVLQERSVISVEDNDNNCDINMENQAKIAALEAELEEEKNHSDQVASENRQLIEENTRLNEQIQELQHQVRTLVPQRGITVNQQIGRDDSAPAELNERFRSLVYSTISELFIENGVHSIQNYVYAGTSAASSCDVNVTVNFGFEN
Protein: Klarsicht, isoform E (M9PGK7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus membrane {ECO:0000256|ARBA:ARBA00004126}.
Interaction partners:
- Muscle-specific protein 300 kDa, isoform G
Sequence:
MEMQQENETGREGVIPNSEKEVALISNQETEKAAMISGGKEGSVRDLESPNETATTQKIEHTTKPLKLDGIFAMPATPPNRAGLTTKSASSSRSSSLKKQRRGSRGSANLNVAGTGDGAPKRSAPGGGQLNYGTNSVGNDLMKQSQSMTSLKASNEEQQESRDVIQAKLHLERPYNSLKKNSHSNKMHRYSWGSGNSQCSSTSLHSSATLGLGSSGKDDLWAAIQTNYNYIMDTNLLDTCKEARCEIEGAATVLEKSSECSFKMLDETQRPEGLCEDPKELRRWLREMENKLESSPTITELTLFGNAELQRHLAVHSVLYHEIASHARVVSSCIRAAEKEQQLQQQQQLSSQQPASLTSNCSSESTSESATKSSSLSSGFASDPVTTPIGTAAAAPPSSSTHPSKKGEGNLERLRDRYHLLYLKAFELQLCLDNLLRKRSSAANGLDDDEDEEEDTEDDSFGYEGEATEDDLNEVNSDLDLENSESKSATPAELILQRCQIAATQIVCGLDETQSQSRSQQVPSQAKSPSADQPRDCLAPQKPGDEADEELEEEDEDPDIGTDVVDFLIAKRSWRQVNHPNPSGTATLTDFEADSESSDFEQVQQLSRRGLPPTVGSTRRVLNLIEMPQSSNSNISSSNSLLQQRNHNIGNKMLPNKAHGKNIAVAVITPNSHGNTSHGHGLGHGLGHELNKSPLGLRKTRHHHNDTSKFNRSNRKSKNCAIFYFKHLDTDNEQGNAAGSDLQSEDDPSLIHRRRAGGDILKSADASTDDDDEGWLYTATAAATLEVATAATAAPTAAAATSSVDGLQSTAVSSTTATGGPLPPSDDSDKENKVALVSATTITAAATATATSIATLHSSNYDSSSACSSSNSNSNSNSNSNGRLTETSATSRVTQLQMQIHSQSQSQSQMELQINGNAIDGRHIISNNNCYSSMQHQPQNNNEGEAAEDLAKIKMGDDEAAADMANGNATKSQQMSNGVYSRADSCNFTVWAAETVASCHLPPRSPAKSAKSSKSQASNATVSGSTLVSPVKGKVSHDSIKQLVLEAEHLVRDAQETALKTPTKQKHSIIKISSTVKKREVTMPHPIKQRVEEWLEHQPSTPQLLTRSHTHELLPSCKPDDCEASGEASETDSVPQAGAGVNGGAPNGAGSDTSEGFTDSIATCMQTSTNSYGNSTERIGGSAEPIGQPVTPLGFGSSNQSLNVKIVKRSQTRRKSERPWSVSCLSQLTTDAAQLTTARIVENSPSGLASHSISESALDSLSPGPRPRAASSSGTGSNAAKKADSKGSLRRRKARKKRISAASAGRKSDSGSELGGDLTQTLMKSCESMSSQQLQEFTNALLSIQKGAVVAPLSPKGDVSGVPSLADGEGGETQLMLPKFRVGSFTTAGLLATDTRLGALAALSNYMNEDEQQAAPKPVQTRLKELSTEDHHSSISETAWDNYQEKYNSENYSEGFDSDAARRLLEFGDDYRNFIDSQSDCCSSLSAANNLDSFSPPRMDSLQKHELKTLHINQDTITSTVDHARRQRALELQYERRRKTLEVRRKSCQDMDESLMASPQSDQQQQQLQVTPSLSASATALMTTPKIQSTSHQISHRAESVGRKLDFGGMSHSAQSLLRRTSESDTSTRRRRTVTADERRRSSRNLEKCIKLIPATTSSSSGSDSEDGEQEMRSLLQQSRDRLDDTRALKIRCHLLRPEDYNEIINTCRDNIRCLEAVLRGPPGTVLSNHCAGQTKDLLGAWEDLLSWSENASAARKLQQEMSVLKSSLQRLGDKPTPELLDTEPAIQIAVEALKLEQTQLTSYRTNMLRLNASVHSWLTKQERRLQSALEEQEQQQESEQLKQQKLVEEEKGADVQKELASTGAVAITVTDSNGNQVEALATGEASTSTPAWDVHTLMSSEQEFHKHLKNEVSDMYSSWDEADARINTQLEMLTNSLIAWRQLESGLSEFQLALGQDRGTLKGLEGALDKGQATPVELAQNVKLVAKLLSEKVHVSQEQLLAVQQHLDPNHIYHITKFTASNGSLSDSGISDGGATSDGGLSERERRLGVLRRLAKQLELALAPGSEAMRSIAARMESAEADLKHLQNTCRDLIVRTAASHQQKQQIQQNQTQQVSPKANGHIKKQAAKGKAEPQSPGRRGKGARKARQAKKAGEDQQVEEPSLSPEQQKMVLKQLKTLTSGDGGDDPSDDPSLLFNLESSEEDGEGADPAQTSKRGWAWRIARAAVPMQVALFTIFCAACLMQPNCCDNLNNLSMSFTPQLRYIRGPPPI
Protein: Major DNA-binding protein (P17470)
Organism: Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)
Function: Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA.
Subcellular location: Host nucleus {ECO:0000255|HAMAP-Rule:MF_04007}. Note=In the absence of DNA replication, found in the nuclear framework-associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments). {ECO:0000255|HAMAP-Rule:MF_04007}.
Interaction partners:
Sequence:
METKPKTATTIKVPPGPLGYVYARACPSEGIELLALLSARSGDADVAVAPLVVGLTVESGFEANVAVVVGSRTTGLGGTAVSLKLTPSHYSSSVYVFHGGRHLDPSTQAPNLTRLCERARRHFGFSDYTPRPGDLKHETTGEALCERLGLDPDRALLYLVVTEGFKEAVCINNTFLHLGGSDKVTIGGAEVHRIPVYPLQLFMPDFSRVIAEPFNANHRSIGENFTYPLPFFNRPLNRLLFEAVVGPAAVALRCRNVDAVARAAAHLAFDENHEGAALPADITFTAFEASQGKTPRGGRDGGGKGPAGGFEQRLASVMAGDAALALESIVSMAVFDEPPTDISAWPLCEGQDTAAARANAVGAYLARAAGLVGAMVFSTNSALHLTEVDDAGPADPKDHSKPSFYRFFLVPGTHVAANPQVDREGHVVPGFEGRPTAPLVGGTQEFAGEHLAMLCGFSPALLAKMLFYLERCDGGVIVGRQEMDVFRYVADSNQTDVPCNLCTFDTRHACVHTTLMRLRARHPKFASAARGAIGVFGTMNSMYSDCDVLGNYAAFSALKRADGSETARTIMQETYRAATERVMAELETLQYVDQAVPTAMGRLETIITNREALHTVVNNVRQVVDREVEQLMRNLVEGRNFKFRDGLGEANHAMSLTLDPYACGPCPLLQLLGRRSNLAVYQDLALSQCHGVFAGQSVEGRNFRNQFQPVLRRRVMDMFNNGFLSAKTLTVALSEGAAICAPSLTAGQTAPAESSFEGDVARVTLGFPKELRVKSRVLFAGASANASEAAKARVASLQSAYQKPDKRVDILLGPLGFLLKQFHAAIFPNGKPPGSNQPNPQWFWTALQRNQLPARLLSREDIETIAFIKKFSLDYGAINFINLAPNNVSELAMYYMANQILRYCDHSTYFINTLTAIIAGSRRPPSVQAAAAWSAQGGAGLEAGARALMDAVDAHPGAWTSMFASCNLLRPVMAARPMVVLGLSISKYYGMAGNDRVFQAGNWASLMGGKNACPLLIFDRTRKFVLACPRAGFVCAASNLGGGAHESSLCEQLRGIISEGGAAVASSVFVATVKSLGPRTQQLQIEDWLALLEDEYLSEEMMELTARALERGNGEWSTDAALEVAHEAEALVSQLGNAGEVFNFGDFGCEDDNATPFGGPGAPGPAFAGRKRAFHGDDPFGEGPPDKKGDLTLDML