wanglab/gogpt-training-data huggingface dataset:
Protein: 3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (Keen to exit meiosis leaving testes under-populated protein) (Ketu) (YTH domain-containing protein C2) (mYTHDC2) (B2RR83)
Organism: Mus musculus (Mouse)
Function: 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability. Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs. Acts by binding and promoting degradation of m6A-containing mRNAs: the 3'-5' RNA helicase activity is required for this process and RNA degradation may be mediated by XRN1 exoribonuclease. Required for both spermatogenesis and oogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:29033321, ECO:0000269|PubMed:29087293, ECO:0000269|PubMed:29360036}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9H6S0}.
Interaction partners:
- 5'-3' exoribonuclease 1
- Meiosis-specific coiled-coil domain-containing protein MEIOC
- ATP-dependent RNA helicase DHX8
- ATP-dependent RNA helicase A
- N
- Pre-mRNA-splicing regulator WTAP
- RNA demethylase ALKBH5
- N
- Protein virilizer homolog
- Zinc finger CCCH domain-containing protein 13
Sequence:
MSRPSSVSPRPPAPSGGGTGGGGGGSGGGGGGGGGGPASCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQVPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQREEKQQTTLTEWYSAQENTFKPESQRQRAVASVSEEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDVDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFTSQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGNDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAILIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCTIADFLMKAPEPPPALIVRNAVQMLKTIDAMDAWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGTFSDHMALLRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENVILTGPKEKKVRFHPTSVLSQPQYKKIPPANGQAAAIQALPTDWLIYDEMTRAHRIANIRCCSAVTPVTVLVFCGPARLASNALQEPSSFRADGIPNDSSDSEMEDRTTANLAALKLDEWLNFKLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSTADTEFADGSTTGERVLMKSPSPALHPPQKYKDRGILHPKRSTDDRSDQSSVKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPIRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSMVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPQVGEQLLQLWERLPLGEKTTSD
Protein: Iron-sulfur cluster-binding protein (Q726S3)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- LUD domain-containing protein
- Heterodisulfide reductase, iron-sulfur-binding subunit, putative
- LUD domain-containing protein
- Glycolate oxidase iron-sulfur subunit
- Pyruvate:ferredoxin oxidoreductase
- Heterodisulfide reductase, A subunit
- Hydrogenase, iron-sulfur cluster-binding subunit, putative
- DRTGG domain-containing protein
- Phosphate acetyltransferase
- Periplasmic [NiFe] hydrogenase large subunit
Sequence:
MQNSKTLKEYRKELQESLDNEFLRNAMDKFAVAYRASRANAFKDIDEKAIIAEVADAKDHAAKNMDTLYAQFKAEAEKRGVKVHLARTAAEANEIIARIARDNNCKKAIKSKSMTAEETHLNHRLEEDNVEVIETDLGEWIIQMRHEGPSHMVMPAIHLSRYQVADLFSEVTKQKQEVDIQRLVKVARRELRTHFATADMGISGANFAVAETGTIGLVTNEGNARLVTTLPRVHVALAGLDKLVPTLHDALRSLKVLPRNATGQAITSYVTWIGGANECEACVDGRKEMHIVFLDNGRRALAEDPLFSQVLRCVRCGACANVCPVYRLVGGHKMGHIYIGAIGLILTYFFHGRDKARNLVQNCINCESCKHICAGGIDLPRLIKEIRARLNEEEGMPVETTLMGKMLKNRKLFHTLLRFAKWAQKPVTGGTPYIRHLPQIFAKDHGFKALPAIADKPFRDEWETVRPRIAKPKLRIALFSGCVQDFVYPEQMKAAVKVIASQNVDIDFPMDQSCCGLPVQMMGEREATIEVARQNVMAFDAARYDYIVTLCASCASHLKETYPKLLTGHPEMTTRVRQFSNKIIDFSSFVHDVLGMKSDAFKGGSNEKVAYHSSCHLCRGLGVVEQPRNLIAASGATYCKAEEEDVCCGFGGTFSAKFPELSAELLRKKLDNVEATGAGRLVADCPGCIMQLRGGMEKRGGKVKVGHVAELLAENLK
Protein: Calcium/calmodulin-regulated receptor-like kinase 2 (AtCRLK2) (EC 2.7.11.1) (Q9LFV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Transcription factor ICE1
Sequence:
MVNRSDLVVIGISVGLALGLLLALLLFFAIKWYYGRSHLRRCANEQNSPTLPVHTAKRGVVIPDDRANTESSQPPENGAPTQHQPWWNNHTKDLTVSASGIPRYNYKDIQKATQNFTTVLGQGSFGPVYKAVMPNGELAAAKVHGSNSSQGDREFQTEVSLLGRLHHRNLVNLTGYCVDKSHRMLIYEFMSNGSLENLLYGGEGMQVLNWEERLQIALDISHGIEYLHEGAVPPVIHRDLKSANILLDHSMRAKVADFGLSKEMVLDRMTSGLKGTHGYMDPTYISTNKYTMKSDIYSFGVIILELITAIHPQQNLMEYINLASMSPDGIDEILDQKLVGNASIEEVRLLAKIANRCVHKTPRKRPSIGEVTQFILKIKQSRSRGRRQDTMSSSFGVGYEEDLSRVMSRIKDQHVELGLLAGVKEENHQERNIATT
Protein: Putative transcription factor bHLH041 (Basic helix-loop-helix protein 41) (AtbHLH41) (bHLH 41) (Transcription factor EN 51) (bHLH transcription factor bHLH041) (Q9LTS4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor bHLH30
- Transcription factor bHLH133
- Transcription factor bHLH123
- Transcription factor bHLH36
- Transcription factor bHLH70
- Transcription factor bHLH144
- Transcription factor bHLH94
- Transcription factor bHLH106
- Transcription factor bHLH147
Sequence:
MMHLILSCSYLISMDGYYNEASEEPSSSSSSGSLARSLFHEYRQSVIPLQNGHVPSMAFMNNLPYVEIRPQESQRLAFNDTQRLFYQMKIEASLREWFPEDFNRKSSPANSDYLRPPHYPSSSSSSLSPNNISEYSSLLFPLIPKPSTTTEAVNVPVLPPLAPINMIHPQHQEPLFRNRQREEEAMTQAILAVLTGPSSPPSTSSSPQRKGRATAFKRYYSMISDRGRAPLPSVRKQSMMTRAMSFYNRLNINQRERFTRENATTHGEGSGGSGGGGRYTSGPSATQLQHMISERKRREKLNESFQALRSLLPPGTKKDKASVLSIAREQLSSLQGEISKLLERNREVEAKLAGEREIENDLRPEERFNVRIRHIPESTSRERTLDLRVVLRGDIIRVDDLMIRLLEFLKQINNVSLVSIEARTLARAEGDTSIVLVISLRLKIEGEWDESAFQEAVRRVVADLAH
Protein: Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y) (Proteasome subunit beta-1) (beta-1) (P28072)
Organism: Homo sapiens (Human)
Function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB6 displays a peptidylglutamyl-hydrolizing activity also termed postacidic or caspase-like activity, meaning that the peptides bond hydrolysis occurs directly after acidic residues.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12181345, ECO:0000269|PubMed:34711951}. Nucleus {ECO:0000269|PubMed:12181345, ECO:0000269|PubMed:34711951}. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9. {ECO:0000269|PubMed:34711951}.
Interaction partners:
- Proteasome subunit alpha type-2
- Proteasome subunit alpha type-7
- 26S proteasome non-ATPase regulatory subunit 4
- Proteasome subunit alpha type-1
- Proteasome subunit beta type-7
- Proteasome subunit beta type-5
- Proteasome subunit beta type-4
- Proteasome subunit alpha type-4
- Proteasome subunit alpha type-5
- Proteasome subunit alpha type-6
Sequence:
MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA
Protein: Radial spoke head protein 9 homolog (Q5TYW6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the axonemal radial spoke head which plays an important role in ciliary motility. Required for motility of olfactory and neural cilia and for the structural integrity of ciliary axonemes in both 9+0 and 9+2 motile cilia. Essential for both the radial spoke head assembly and the central pair microtubule stability in ependymal motile cilia (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:27687975}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9D9V4}. Cell projection, kinocilium {ECO:0000269|PubMed:27687975}.
Interaction partners:
- Radial spoke head component 4A.
- Radial spoke head 1 homolog
- Radial spoke head 3
- Dynein axonemal assembly factor 1
- Coiled-coil domain-containing protein 39
- Dynein regulatory complex subunit 2
- NME/NM23 family member 8
- Dynein, axonemal, heavy chain 5.
- Dynein regulatory complex protein 1
- Coiled-coil domain-containing protein 40
Sequence:
MDSDSLHYSLDLAAANGLTLSSEQRAALQSSLLIVKRNYKFSRVLFWGKILGIKSDYFIAQGVEDDELKNRKSLYSLNCVDWHLLPPATESMIADVALAATGRFTGDPSHEYEHTEIRTEGEGDEATHEEVTVKVIEASRLAAIVSNIDKDVSVVPRGAFIKSPNGKVQTNRSFGGLHPTEAAKLRNYLHFREPVNLRNKSILEMSELNPALDFLDPLSEDILKGSWSLQLDRGGTVCVLRSLLWLGFTFFHVPQTPQHGYIYMGDGLMNLDLPFML
Protein: F-box and leucine-rich repeat protein 18 (E9PYR1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MPHPTWRPHRVHPGASGSTSRRAPQPRPLPGSLWSCGRAGFEHPYAGRLGDCEAAAPAASSGEDMSSEEEAAAEAAGDTHLLGFSDEILLHILSHVPSTDLVLSVRRTCRKLAALCLDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLSGSTIEHVARCHSLVKVNLSGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPKSWLNGSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLLRKAEDDIDSSILETLVESCCNLHHLNLSAAHHHSSDGLGRHLCQLLARLCHLRSLSLPVCSVADSAPRPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNPFVGQSAPQPASVFWSLLKKLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLTFLRHLTLAQLPGMLTGSGLVSIGLQCQHLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNANAQFFQALGQCSSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHMFTGESLTTCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPMLHLDEITLFKSRVAEEPPNLWW
Protein: Glycine--tRNA ligase beta subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase beta subunit) (GlyRS) (P00961)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm.
Interaction partners:
- Glycine--tRNA ligase alpha subunit
- Isoleucine--tRNA ligase
- Leucine--tRNA ligase
- Valine--tRNA ligase
- Proline--tRNA ligase
Sequence:
MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLDAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFTEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRVADISLLQ
Protein: tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (O36015)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03162}.
Interaction partners:
- tRNA
- tRNA
- tRNA
- tRNA
- tRNA
- tRNA
- tRNA
- tRNA
- Multisubstrate pseudouridine synthase 7
- tRNA
Sequence:
MGRSSKDKRDAYYRLAKEQGWRARSAFKLLQLNEQFNLFEGAKRVVDLCAAPGSWSQVLSRELLKNIDTSIAADEKPMIVAVDLQPMAPIDGVCTLQLDITHPNTLSIILSHFGNEPADLVVSDGAPDVTGLHDLDEYIQAQILLAAFNLAVCVLKPGGKFVAKIFRGRDVSLLYSQLRLMFRKVSCAKPRSSRASSIESFVVCEDFNPPSNFQPDLTKPLCVIDPTNAHEIAPFIACGDLDGYDADATYPVEINMKKATLDVIQPPTAPPYKRAIELKHSKMMS
Protein: HTH-type transcriptional repressor AllR (Negative regulator of allantoin and glyoxylate utilization operons) (P0ACN4)
Organism: Escherichia coli (strain K12)
Function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS-allA intergenic region. Binding to DNA is abolished by glyoxylate.
Interaction partners:
- Ureidoglycolate lyase
- HTH-type transcriptional activator AllS
- Glyoxylate carboligase
Sequence:
MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP
Protein: Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (Q5XFW8)
Organism: Rattus norvegicus (Rat)
Function: Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum.
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:P55735}; Peripheral membrane protein {ECO:0000250|UniProtKB:P55735}; Cytoplasmic side {ECO:0000250|UniProtKB:P55735}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P55735}; Peripheral membrane protein {ECO:0000250|UniProtKB:P55735}; Cytoplasmic side {ECO:0000250|UniProtKB:P55735}. Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P55735}. Lysosome membrane {ECO:0000250|UniProtKB:P55735}. Note=In interphase, localizes at both sides of the NPC. {ECO:0000250|UniProtKB:P55735}.
Interaction partners:
- GATOR2 complex protein MIOS
- GATOR2 complex protein WDR24
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein Nup133
- Nuclear pore complex protein Nup85
- Nucleoporin 160
- LOC683983 protein
- Nucleoporin Nup37
- Nuclear pore complex protein Nup107
- Protein transport protein Sec31A
Sequence:
MVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHSGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWREEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNMWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASITEGQQNEQ
Protein: Acylphosphatase-2 (EC 3.6.1.7) (Acylphosphatase, muscle type isozyme) (Acylphosphate phosphohydrolase 2) (P56375)
Organism: Mus musculus (Mouse)
Interaction partners:
- Aldehyde dehydrogenase X, mitochondrial
- Aldehyde dehydrogenase family 3 member A2
- Acylphosphatase-1
- Alpha-aminoadipic semialdehyde dehydrogenase
- Acetyl-coenzyme A thioesterase
- 4-trimethylaminobutyraldehyde dehydrogenase
- Acetyl-coenzyme A synthetase 2-like, mitochondrial
- Aldehyde dehydrogenase, mitochondrial
- Acetyl-coenzyme A synthetase, cytoplasmic
Sequence:
MLLGRRLAAMTELLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVDAMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSDFSIRY
Protein: I[[h]] channel, isoform B (A1Z9N8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNPESNTITAVVNALAAEADDCKDDDMDLKENLLHGSESSIAEPVQTIREGLPRPRSGEFRALFEGNTP
Protein: GATA binding protein 5 (F1NZV5)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MYQGLALAPNHGQSAYSHDSGNFLHSSAGSPVYVPTTRVPSVLQTLPYLQSCEPHQSHLGNPPGWAQSSGETTAFNAGSPHPPSGFSYPHSPPGSSPPGRDGAYQGPLLLGGGGREQYGNALVRSVNGSYSSPYPAYVTPELPPSWTAGHFESSVLHSLQTRQAALPGRRSTFEYLEEFPGDGRECVNCGAMSTPLWRKDGTGHYLCNACGLYHKMNGINRPLKPQKRLSSSRRAGLCCTNCHTTNTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNITKGKTSTGSTTSATNSPSSITNSDSTVTLKSEPSTTSQYPGQGIVSVSQAQSQSDEALAGGEFKFEPEDYPFSPSSMAPQPGLSVPLRQDSWCALALA
Protein: Possible transcriptional regulatory protein (Probably MarR-family) (P71699)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized HTH-type transcriptional regulator Rv0043c
- Chaperone protein HtpG
Sequence:
MSVVRSIGKKMQRISGPNALAVKGRPTQVYGHTHVRLDCRFMADSEFTAPEVTQLAEGLHRALSKLISMLRRGDPNGAAAGDLTLAQLSILVTLLDQGPIRMTDLAAHERVRTPTTTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHGESLANRRAALAALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA
Protein: UPF0479 membrane protein YFL068W (P0CX99)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized membrane protein YFL067W
- Uncharacterized protein YFL064C
- Uncharacterized protein YFL065C
- Y' element ATP-dependent helicase YFL066C
- Uncharacterized protein YCR108C
- UPF0320 protein YOL166W-A
- Putative uncharacterized protein YHR214C-E
- Putative UPF0320 protein YFL063W
- Uncharacterized protein YHR213W-B
- Uncharacterized protein YHR213W-A
Sequence:
MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFLVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKKFQIPYRVPMIWLDVFQVFFVFLVISQHSLHS
Protein: DNA repair protein RAD51 homolog 3 (J3QKK3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLATACIQHLQLIAEKHKGEEHRKALEDFTLDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLVPALGESWGHAATIRLIFHWDRKQRLATLYKSPSQKECTVLFQIKVSII
Protein: Syndecan (F1DFN3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU000649}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU000649}.
Interaction partners:
Sequence:
MKLPCWITLLLLQTALAQHSKSQPSDDESSGDEPYDDEDFYSGSGSGYPDIKVRPSSVGVVFTTEEPLPLSTTQATGPAPSASPAAEPSSPPPPEVERESGLGQDVDSKLEIEKKYEEYDEEEEIRPTRKEQEPDTEKVQEREQDRSKATVAPRLTDVPIVFLGSSTVGGATETTTDLEDLGGREEETDEDLYITKETIVLDPSSETDMITDEITTTEFIPTTIPSTTAKPTRPRPILTTPSPTAVRPRQPQTTPSRAAPTESSTRSVMTTTQTQVPDETVNNEVAGPGPSGDFEIRENEVRQNNDLGRGRAVPGEPDLTGNTVDAAGSSAAQLPQKNILERKEVLIAVIVGGVVGALFAAFLVMLLVYRMKKKDEGSYTLEEPKQATVTYQKPDKQEEFYA
Protein: CST complex subunit TEN1 (Protein MERISTEM DISORGANIZATION 1) (Protein telomeric pathways with STN1 homolog) (Q6NME7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the maintenance of meristems and stem cells through the reduction of DNA damage. Promotes telomere integrity by maintaining telomere length and proper architecture of the chromosome terminus. Negatively regulates telomerase repeat addition processivity. Hampers contacts between enzymatically active telomerase and CST complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:23572541}. Chromosome, telomere {ECO:0000269|PubMed:23572541}. Note=Associates transiently with telomeres. {ECO:0000269|PubMed:23572541}.
Interaction partners:
- CST complex subunit STN1
- CST complex subunit CTC1
- Protection of telomeres protein 1a
- Protection of telomeres protein 1b
- Protection of telomeres protein 1c
- Telomerase reverse transcriptase
- Thylakoidal processing peptidase 1, chloroplastic
- Telomere repeat-binding protein 1
- ATP-dependent DNA helicase 2 subunit KU70
- Telomere repeat-binding factor 1
Sequence:
MAKSQIEPGVPITLQELYPSSLFYKEGVSLRVTAMLRGYSVETAIGVIEDGGRSLKINTQNIRDVSFRVGSIYQFIGELHIEQPNNEAILQARTGRNVDGIDMNLYRKTIELLRQFLKEEDNSNMVE
Protein: HLA class I histocompatibility antigen C alpha chain (MHC class I antigen) (Major histocompatibility complex, class I, C) (Q53YP1)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MRVMAPRTLILLLSGALALTETWAGSHSMRYFYTAVSRPGRGEPHFIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSLRNLRGYYNQSEAGSHIIQRMYGCDVGPDGRLLRGYDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQLRAYLEGLCVEWLRRYLKNGKETLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQWDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWEPSSQPTIPIVGIVAGLAVLAVLAVLGAVVAVVMCRRKSSGGKGGSCSQAASSNSAQGSDESLIACKA
Protein: SEC63-like (S. cerevisiae) (Translocation protein SEC63 homolog) (Q6DGY6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYIWPRDQNAEQLRLKSLRRVHGRCLWYRLRLMKSQQSIVPTLKKAALLFGWAVFLLLAYKVSKLDREYQEYNPYEVLNLEAGASVAEIKKQYRVLSLKHHPDKGGDEATFMKLAKAYSALTNEESRKNWEMYGNPDGPRVTSFGIALPAWIVDQKNSMLVLLVYGLAFMVILPVVVGTWWYRSIRYSGDQILINTTQLFMHFMYKTPTMNMKRLVMVLTAAFEFDPRSNKEAIIRPTDNIEVPQLIRELGNINVKKKEPPFCYPYSLKARVLLLAQLARMDVSENIEEDQRFVVKKCPALLQEMINVGCQLTMMATSRGGLRAPRLTSIENCMKLSQMVVQGLQEAKSPLLQLPHFEEEHLRYCISKKYKVRTLQDLVSLKDSDRRNMLRFLGEEKYDEVIGVLGSFPYINMETKLQVLDDEDSNNITAGSIVTVTVILTRKRMSEMFEKEENAPLPAEEVNTEEQGDAKNKTKVWQNKNKGAKKAAKPKKKKLTKKKPVTQQQAKGDKAKQANGNVAGNEVVSKEEEEDLSDKGSESDEAEGNKDSPSERDDESDKQSDTEGDEIARDDEEEWEALQQSIQRRERALLETKSKVTHPVYSLFFPEEKQEWWWLYIADRKEQTLVSMPNHVCTLKDTEEVELKFPAPSKTGNYQYSVILRSDSFMGLDQIKPLKLEVHEAKAMMDNHPQWDIPETEEEEDDQEDSDGIEESEEDEEDND