wanglab/gogpt-training-data huggingface dataset:
Protein: Phosphomethylpyrimidine synthase (EC 4.1.99.17) (Hydroxymethylpyrimidine phosphate synthase) (HMP-P synthase) (HMP-phosphate synthase) (HMPP synthase) (Thiamine biosynthesis protein ThiC) (P9WG79)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
Interaction partners:
- Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
- Thiazole synthase
- Thiamine-phosphate synthase
- FO synthase
- Possible protein ThiS
- KANL3/Tex30 alpha/beta hydrolase-like domain-containing protein
- Phosphoribosylformylglycinamidine cyclo-ligase
- N5-carboxyaminoimidazole ribonucleotide synthase
- Putative DNA processing protein DprA
Sequence:
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPITQ
Protein: Stellate protein CG33247 (Q7KV23)
Organism: Drosophila melanogaster (Fruit fly)
Function: Unknown. In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
Interaction partners:
- Casein kinase II subunit alpha
- Casein kinase II subunit beta
- Stellate protein CG33246
- Segment polarity protein dishevelled
- Stellate protein CG33239/CG33241
- Stellate protein CG33236/CG33240/CG33244/CG33245
- Stellate protein CG33237
- Stellate protein CG33238
- Ste:CG33242
- Stellate protein CG33243
Sequence:
MSSSQNNNSSWIDWFLGIKGNQFLCRVPTDYVQDTFNQMGLEYFSEILDVILKPVIDSSSGLLYGDEKKWYGMIHARYIRAERGLIAMHRKYMRGDFGSCPNISCDRQNTLPVGLSAVWGKSTVKIHCPRCKSNFHPKSDTQLDGAMFGPSFPDIFFSLLPNLTSPLDDPRT
Protein: Nuclear pore complex protein NUP98B (Nucleoporin 98B) (Nucleoporin autopeptidase) (F4ID16)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
Interaction partners:
- Protein SEH1
- Protein RAE1
- Protein transport protein SEC13 homolog B
- Nuclear pore complex protein NUP54
- F7H2.18 protein
- Protein transport protein SEC13 homolog A
- Nuclear pore complex protein NUP107
- Nuclear pore complex protein NUP205
- Nuclear pore complex protein NUP160
- Nuclear pore complex protein NUP88
Sequence:
MFGSSNNNPFGQSSISSPFGTQTHSLFGQTNNNASNNPFATKPFGTSTPFGAQTGSSMFGGTSTGVFGAPQTSSPFGASPQAFGSSTQAFGASSTPSFGSSNSPFGGTSTFGQKSFGLSTPQSSPFGSTTQQSQPAFGNSTFGSSTPFGASTTPAFGASSTPAFGVSNTSGFGATNTPGFGATNTTGFGGSSTPGFGASSTPAFGSTNTPAFGASSTPLFGSSSSPAFGASPAPAFGSSGNAFGNNTFSSGGAFGSSSTPTFGASNTSAFGASSSPSFNFGSSPAFGQSTSAFGSSSFGSTQSSLGSTPSPFGAQGAQASTSTFGGQSTIGGQQGGSRVIPYAPTTDTASGTESKSERLQSISAMPAHKGKNMEELRWEDYQRGDKGGQRSTGQSPEGAGFGVTNSQPSIFSTSPAFSQTPVNPTNPFSQTTPTSNTNFSPSFSQPTTPSFGQPTTPSFRSTVSNTTSVFGSSSSLTTNTSQPLGSSIFGSTPAHGSTPGFSIGGFNNSQSSPLFGSNPSFAQNTTPAFSQTSPLFGQNTTPALGQSSSVFGQNTNPALVQSNTFSTPSTGFGNTFSSSSSLTTSISPFGQITPAVTPFQSAQPTQPLGAFGFNNFGQTQIANTTDIAGAMGTFSQGNFKQQPALGNSAVMQPTPVTNPFGTLPALPQISIAQGGNSPSIQYGISSMPVVDKPAPVRVSPLLTSRHLLQRRVRLPTRKYRPSDDGPKVPFFSDEEENSSTPKADAFFIPRENPRALFIRPVERVKSEHPKDSPTPLQENGKRSNGVTNGANHETKDNGAIREAPPVKVNQKQNGTHENHGGDKNGSHSSPSGADIESLMPKLHHSEYFTEPRIQELAAKERVEQGYCKRVKDFVVGRHGYGSIKFLGETDVCRLDLEMVVQFKNREVNVYMDESKKPPVGQGLNKPAVVTLLNIKCMDKKTGTQVMEGERLDKYKEMLKRKAGEQGAQFVSYDPVNGEWTFKVEHFSSYKLGDEYDV
Protein: Arginine/serine-rich-like splicing factor (At2g17240/T23A1.10) (Expressed protein) (Q9SII4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Calcium load-activated calcium channel
- Endonuclease or glycosyl hydrolase
- Protein yippee-like At5g53940
- Cytosolic sulfotransferase 11
- AT1G11360 protein
- Probable pectinesterase/pectinesterase inhibitor 25
- Vesicle-associated protein 1-2
- Protein ECS1
- At3g56360
- Eukaryotic translation initiation factor 3 subunit D
Sequence:
MASLCSARFLPSPSLDILSTKTKISSDSRSLGCSSSRVFAFSSVHRSSSRRNRNQLQVVSMAPEEEKLTRRNPLDFPIEWERPKPGRRPDIFPKFSPMKTPLPPPMPYDPPEEDEEEEEKKEEEEENPDQEEEEQPEKQQ
Protein: Protein BTG1 (B-cell translocation gene 1 protein) (P62324)
Organism: Homo sapiens (Human)
Function: Anti-proliferative protein.
Interaction partners:
- CCR4-NOT transcription complex subunit 7
- CCR4-NOT transcription complex subunit 8
- Forkhead box protein O3
- Protein arginine N-methyltransferase 1
Sequence:
MHPFYTRAATMIGEIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEKPCKGSGYRCIRINHKMDPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGEDGSICVLYEASPAGGSTQNSTNVQMVDSRISCKEELLLGRTSPSKNYNMMTVSG
Protein: VEL1-related protein AC977.05c (Q9P7U4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm, cytosol {ECO:0000250}. Note=Intracellular soluble fraction. {ECO:0000250}.
Interaction partners:
- UPF0494 membrane protein SPAC212.01c
- NAD-dependent malic enzyme
- Zinc finger protein C25B8.19c
- Transposon Tf2-7 polyprotein
- Transposon Tf2-8 polyprotein
- F-box/WD repeat-containing protein pof1
Sequence:
MIFKNLISLFFIGLATAIRFNLTDLECSRLRGPHCGTYLLKVVGTNATYVGEKSFIGLDALTESKGEFFQRMLEQEPRLIPRLFTIAENDTANFTPLTFTTYLKTCNPQSIENAMIPFVNTVTSEISFDAWAYTAQNSSRITGLSNQLMNSTLYNVQVATCTPGFSALLLDSPTINVFNNEEGMPSWCQPIELIPVCPLDEGFN
Protein: Retinal guanylyl cyclase 1 (RETGC-1) (EC 4.6.1.2) (Guanylate cyclase 2E) (Guanylyl cyclase GC-E) (P51840)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane.
Subcellular location: Membrane {ECO:0000269|PubMed:7831337}; Single-pass type I membrane protein. Photoreceptor outer segment membrane {ECO:0000269|PubMed:7831337, ECO:0000269|PubMed:9153227}; Single-pass type I membrane protein. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q02846}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Guanylyl cyclase-activating protein 1
- Guanylyl cyclase-activating protein 2
- Neurocalcin-delta
- Retinal guanylyl cyclase 2
- Phosphodiesterase
- Guanylate cyclase 2D
- Inosine triphosphate pyrophosphatase
- Phosphodiesterase
- Aryl-hydrocarbon-interacting protein-like 1
- Phosphodiesterase
Sequence:
MSAWLLPAGGFPGAGFCIPAWQSRSSLSRVLRWPGPGLPGLLLLLLLPSPSAFSAVFKVGVLGPWACDPIFARARPDLAARLATDRLNRDLALDGGPWFEVTLLPEPCLTPGSLGAVSSALTRVSGLVGPVNPAACRPAELLAQEAGVALVPWGCPGTRAAGTTAPAVTPAADALYVLLKAFRWARVALITAPQDLWVEAGRALSTALRARGLPVALVTSMVPSDLSGAREALRRIRDGPRVRVVIMVMHSVLLGGEEQRYLLEAAEELGLTDGSLVFLPFDTLHYALSPGPEALAAFVNSSKLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLDLKQVSPLFGTIYDAVFLLAGGVTRARAAVGGGWVSGASVARQMREAQVFGFCGILGRTEEPSFVLLDTDAAGERLFTTHLLDPVLGSLRSAGTPVHFPRGAPAPGPDPSCWFDPDVICNGGVEPGLVFVGFLLVIVVGLTGAFLAHYLRHRLLHMQMVSGPNKIILTLEDVTFLHPQGGSSRKVAQGSRSSLATRSTSDIRSVPSQPQESTNIGLYEGDWVWLKKFPGEHHMAIRPATKMAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQRDIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPALERRGTLAGDVFSLGIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMAQCWAEHPELRPSMDLTFDLFKGINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKGKGVEDTYWLVGRVGFNKPIPKPPDLQPGASNHGISLQEIPPERRKKLEKARPGQFTGK
Protein: Glycine N-acyltransferase (EC 2.3.1.13) (Acyl-CoA:glycine N-acyltransferase) (AAc) (Aralkyl acyl-CoA N-acyltransferase) (Aralkyl acyl-CoA:amino acid N-acyltransferase) (Benzoyl-coenzyme A:glycine N-acyltransferase) (Glycine N-benzoyltransferase) (EC 2.3.1.71) (HRP-1(CLP)) (Q6IB77)
Organism: Homo sapiens (Human)
Function: Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:22475485}.
Interaction partners:
- Bile acid-CoA:amino acid N-acyltransferase
- Gamma-glutamylcyclotransferase
- Aldo-keto reductase family 1 member D1
- N
Sequence:
MMLPLQGAQMLQMLEKSLRKSLPASLKVYGTVFHINHGNPFNLKAVVDKWPDFNTVVVCPQEQDMTDDLDHYTNTYQIYSKDPQNCQEFLGSPELINWKQHLQIQSSQPSLNEAIQNLAAIKSFKVKQTQRILYMAAETAKELTPFLLKSKILSPNGGKPKAINQEMFKLSSMDVTHAHLVNKFWHFGGNERSQRFIERCIQTFPTCCLLGPEGTPVCWDLMDQTGEMRMAGTLPEYRLHGLVTYVIYSHAQKLGKLGFPVYSHVDYSNEAMQKMSYTLQHVPIPRSWNQWNCVPL
Protein: Histone-lysine N-methyltransferase mes-2 (EC 2.1.1.356) (E(z) homolog) (Maternal-effect sterile protein 2) (O17514)
Organism: Caenorhabditis elegans
Function: Polycomb group (PcG) protein. Catalytic subunit of a the mes-2/mes-3/mes-6 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. In association with the nfya-1-NF-Y complex, may play a role in repressing the expression of the homeobox protein egl-5 in tissues such as the head. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes-6 complex may participate in the global inactivation of the X chromosomes in germline cells. This complex is required to exclude mes-4 from the inactivated X-chromosomes in germline cells. Required for small-RNA-induced H3K27 trimethylation. Involved in the negative regulation of lifespan in a germline-independent fashion.
Subcellular location: Nucleus {ECO:0000269|PubMed:9609829}.
Interaction partners:
- Polycomb protein mes-6
- Polycomb protein mes-3
- Probable histone-binding protein lin-53
- Probable histone-binding protein rba-1
- JmjC domain-containing protein
- PHD-type domain-containing protein
- Multifunctional procollagen lysine hydroxylase and glycosyltransferase
- E3 ubiquitin-protein ligase RING2 homolog spat-3
- Polycomb group RING finger protein 3 homolog mig-32
- Histone-lysine N-methyltransferase set-25
Sequence:
MSNSEPSTSTPSGKTKKRGKKCETSMGKSKKSKNLPRFVKIQPIFSSEKIKETVCEQGIEECKRMLKGHFNAIKDDYDIRVKDELDTDIKDWLKDASSSVNEYRRRLQENLGEGRTIAKFSFKNCEKYEENDYKVSDSTVTWIKPDRTEEGDLMKKFRAPCSRIEVGDISPPMIYWVPIEQSVATPDQLRLTHMPYFGDGIDDGNIYEHLIDMFPDGIHGFSDNWSYVNDWILYKLCRAALKDYQGSPDVFYYTLYRLWPNKSSQREFSSAFPVLCENFAEKGFDPSSLEPWKKTKIAEGAQNLRNPTCYACLAYTCAIHGFKAEIPIEFPNGEFYNAMLPLPNNPENDGKMCSGNCWKSVTMKEVSEVLVPDSEEILQKEVKIYFMKSRIAKMPIEDGALIVNIYVFNTYIPFCEFVKKYVDEDDEESKIRSCRDAYHLMMSMAENVSARRLKMGQPSNRLSIKDRVNNFRRNQLSQEKAKRKLRHDSLRIQALRDGLDAEKLIREDDMRDSQRNSEKVRMTAVTPITACRHAGPCNATAENCACRENGVCSYMCKCDINCSQRFPGCNCAAGQCYTKACQCYRANWECNPMTCNMCKCDAIDSNIIKCRNFGMTRMIQKRTYCGPSKIAGNGLFLLEPAEKDEFITEYTGERISDDEAERRGAIYDRYQCSYIFNIETGGAIDSYKIGNLARFANHDSKNPTCYARTMVVAGEHRIGFYAKRRLEISEELTFDYSYSGEHQIAFRMVQTKERSEKPSRPKSQKLSKPMTSE
Protein: Homeobox-containing protein PKNOX1 (PBX/knotted 1 homeobox 1) (Q96I87)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSEPDAEGVSPPPVESQTPMDVDKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTISPQGIVVPASALQQGNVAMATVAGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEEDAGALAPAHISGLVLENSDSLQ
Protein: Elongator complex protein 1 (O59704)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the elongator complex, a multiprotein complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. ELP1 binds to tRNA, mediating interaction of the elongator complex with tRNA (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Elongator complex protein 3
- Elongator complex protein 2
- Elongator complex protein 4
- Elongator complex protein 5
- Elongator complex protein 6 homolog
- Protein kti12
- Cytoplasmic tRNA 2-thiolation protein 1
- Adenylyltransferase and sulfurtransferase uba4
- Ubiquitin-related modifier 1
- DNA replication licensing factor mcm5
Sequence:
MKNLVTHLHHVFPNVNGSIKALAFNSISDKIYVVCGLDNENPGIEIYEISENDDVSKLVEFDSPSFVSDNGDIDEIQSMQFLGEPMAICLSLKGGDIVMVKVDPSPEEAPWEIIGNVENGIVASCWSTDEQVFCIITGGDTILFMTKNFDIISETSLSDADLNEFNKHISVGWGRSETQFRGKRVRAKLRDPTLPEKIDEGKLSDVDDGKTYICWRGDSQYVSINRLEKGPRRAIRVYSREGLLDSISEPQDGQQSLLSWKPSGSVLATIKSDSSDNSSKVIFFERNGLRHGEFSLRRREDEKYTGLAWNVSSSILAVSTENSVMLWTTGNYHWYLKKEINIPQNALISWHPEHANTLYITGKNHIEKVVFDLKYVTEFSTSPNDFGLIPVIDGSSLLVTPLSLCNIPPPMCRYKLSLDYNVQMTSINATSDMLFAADDRRLTAFTFNSQEDIAKFGEFDISTYAEGLNFKSLLGLSGNQVLLLADGTNNCSKFFVFQCDEDNESLKLLASESFESCILNASYCSEMLFFQTSSGKLISYNLNVKSIESISLSFPKPCSDFVVVPVHETFVPIGLTSYGRLYAEQRLLSTGVLSFFCTERFVLFTTTKNLLKFVHLVSTVDDLQVVEDDAVDRHDERCRVVERGSKIVASMPSKMAVVLQMPRGNLETIYPRIMVLDGVRTYIKALKYGDAFKVCRTHRLDLNILFDYDPDLFLKNIPVFVDGLYRVDYLDLFLTSLKPENVTTGMYSDTSKSQSQQSVTTIDNKVNLLCKIIREHLTSKYGDTHFQAIITSYLCESPPKIEAALGMISGLIKAQSETVDLAIEHMCFLVDVNMLFDHALGLYDLKLALLIAQQSQKDPREYVPFLHEFQKQESLRRKFNIDCYLKRYERALGHLKEMENAFDEFKNFTIQHKLYPRALELYKYDKEAQKEVLIIFAQYLRENGKSNEAAIAYESVGKISEAIEAYKSAGMWRECLSILQQTTNSEDLIRETAEDLASLCIEKREHCDAGSINLLYLSNPREAVIQMCKGSQYSEAIRIARATGDSSIYKDLLISVLGESFGEASELVADFRNQIKSQTERILVLREKKKEDPISWMEGTMEDQTPDDISLASTSLSTNRSLYTQYTKSSNSSKMTRNTSKNNRRLERKRARGKKGTVFEEEYLVNSLRRLIARVEEIRPEVHRLLEALVRCNMTTQASELQRNFANVIGTIGEKVIPILSVPVSTFETALGEQPQAPVVPNVKPFEKLSILI
Protein: Dual-specificity RNA pseudouridine synthase RluA (EC 5.4.99.28) (EC 5.4.99.29) (23S rRNA pseudouridine(746) synthase) (Ribosomal large subunit pseudouridine synthase A) (rRNA pseudouridylate synthase A) (rRNA-uridine isomerase A) (tRNA pseudouridine(32) synthase) (P0AA37)
Organism: Escherichia coli (strain K12)
Function: Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs.
Interaction partners:
- tRNA pseudouridine synthase D
- RNA polymerase-associated protein RapA
- Dual-specificity RNA pseudouridine synthase RluF
- tRNA pseudouridine synthase B
- Ribosomal small subunit pseudouridine synthase A
- tRNA pseudouridine synthase A
- Ribosomal large subunit pseudouridine synthase B
- Ribosomal large subunit pseudouridine synthase E
- tRNA uridine
- tRNA modification GTPase MnmE
Sequence:
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
Protein: Armadillo repeat containing 6 (cDNA FLJ50945, highly similar to Armadillo repeat-containing protein 6) (B4E1N1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLSDLQESVASSRPQEVSAYLTRFCDQCKQDKACRFLAAQKGAYPIIFTAWKLATAGDQGLLLQSLNALSVLTDGQPDLLDAQGLQLLVATLTQNADEADLTCSGIRCVRHACLKHEQNRQDLVKAGVLPLLTGAITHHGHHTDVVREACWALRVMTFDDDIRVPFGHAHNHAKMIVQENKGLKVLIEATKAFLDNPGILSELCGTLSRLAIRNEFCQEVVDLGGLSILVSLLADCNDHQMRDQSGVQELVKQVLSTLRAIAGNDDVKDAIVRAGGTESIVAAMTQHLTSPQVCEQSCAALCFLALRKPDNSRIIVEGGGAVAALQAMKAHPQKAGVQKQACMLIRNLVAHGQAFSKPILDLGAEALIMQARSAHRDCEDVAKAALRDLGCHVELRELWTGQRGNLAP
Protein: Sex comb on midleg-like protein 2 (Q9UQR0)
Organism: Homo sapiens (Human)
Function: Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- E3 ubiquitin-protein ligase RING2
- Polycomb complex protein BMI-1
- Chromobox protein homolog 8
- E3 SUMO-protein ligase CBX4
- Polycomb group RING finger protein 2
- Chromobox protein homolog 6
- Polycomb group RING finger protein 1
- Polycomb group RING finger protein 6
- E3 ubiquitin-protein ligase RING1
- Chromobox protein homolog 2
Sequence:
MGQTVNEDSMDVKKENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEAIDKKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPPGTSVPIVKNIAKTESSPSEASQHSMQSPQKTTLILPTQQVRRSSRIKPPGPTAVPKRSSSVKNITPRKKGPNSGKKEKPLPVICSTSAASLKSLTRDRGMLYKDVASGPCKIVMSTVCVYVNKHGNFGPHLDPKRIQQLPDHFGPGPVNVVLRRIVQACVDCALETKTVFGYLKPDNRGGEVITASFDGETHSIQLPPVNSASFALRFLENFCHSLQCDNLLSSQPFSSSRGHTHSSAEHDKNQSAKEDVTERQSTKRSPQQTVPYVVPLSPKLPKTKEYASEGEPLFAGGSAIPKEENLSEDSKSSSLNSGNYLNPACRNPMYIHTSVSQDFSRSVPGTTSSPLVGDISPKSSPHEVKFQMQRKSEAPSYIAVPDPSVLKQGFSKDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHEIDGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLKEGKYS
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q9GSP5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNKADVNRRVLAIQAKKKRHKSRKRGKQNGTNPQEQSNSSQNQNPKPSSNPIPEPNRSSENLQAPDNANNSHLNAPSSAAFSKATATATASTSSGGSAGTPDQYQPPKKTQAKAKPNTQKEHQQQPPRSSSNESYESETFSDNEDQELMEDYCKGGYHPVNIGDLFHDRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYPSLVSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQRDERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLR
Protein: Cytochrome P450 26A1 (G3V861)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004406}. Microsome membrane {ECO:0000256|ARBA:ARBA00004174}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004174}.
Interaction partners:
- Retinal dehydrogenase 2
- Retinol dehydrogenase 10
- Retinaldehyde dehydrogenase 3
- Lecithin retinol acyltransferase
- Aldehyde dehydrogenase 1A1
- Dehydrogenase/reductase
- Cytochrome P450 1A2
- Dehydrogenase/reductase SDR family member 9
- NADP-retinol dehydrogenase
- Short chain dehydrogenase/reductase family 16C, member 5
Sequence:
MGLPALLASALCTFVLPLLLFLAALKLWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGAGCLSNLHDSSHKQRKKVIMQAFNREALQCYVPVIAEEVSGCLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPGPAGGGEDEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGVKARNLIHARIEENIRAKIRRLQAAEPDAGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSHHEDKLDMETLEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADSFTNKEEFNPDRFTSLHPEDTSRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARRCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFQGDI
Protein: Zinc finger protein 256 (Bone marrow zinc finger 3) (BMZF-3) (Q9Y2P7)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:18060868}.
Interaction partners:
Sequence:
MAAAELTAPAQGIVTFEDVAVYFSWKEWGLLDEAQKCLYHDVMLENLTLTTSLGGSGAGDEEAPYQQSTSPQRVSQVRIPKALPSPQKTNPCEICGPVLRQILHLVEHQGTHHGQKLYTDGACRKQLQFTAYLHQHQKQHVGQKHFRSNGGRDMFLSSCTFEVSGKPFTCKEVGKDFLVRSRFLQQQAAHTRKKSNRTKSAVAFHSVKNHYNWGECVKAFSYKHVRVQHQGDLIRERSYMCSECGKSFSTSCSLSDHLRVHTSEKPYTCGECGKSYRQSSSLITHRRIHTGVRPHQCDECGKLFNRKYDLLIHQRVHTGERPYKCSECGKSFSHSSSLITHQRIHTGMRPYECSECGKSFIHSSSLITHQRVHTGTRPYMCSECGKSFSQSCHLIKHRRLHIGEGPYECSECGKLFTYRSRFFQHQRVHTGVRSHECHECGKLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSYLISHWKVHTGARPYECGECGKSFTHSSTLLQHQRVHTGERPYECNECGKFFSQSSSLIRHRRSHTGERPYECSECWKSFSNHSSLVKHRRVHTGERPYECSECGKSFSQSSNLTNHQRIHSGERPYECSDCGKFFTFNSNLLKHQNVHKG
Protein: Nucleobase/nucleoside transporter 8.1 (Q386F1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MALGFSSAGEVYMYATCILLGVSLLMPLNALVSAPRFMVDYYKYVSGKEDAEPNLPFFWKNIFTFYNVVSLASQVIAGPTVLTRAARRLSLSVRFALSITLMMSEVFVVLMMPVIKVPQTVAIVLLCLVTIFAGIGKSYHEATCYVLVASMPSKFMSAVMFGVSLCGVITSTLQCIIKASMEDTYESVLTQSYIYFSLGLLIMAGTLAMALCLRYNSYAQEHVAEYRMLKLQEQGVDAESQNDENEPVAEGKGEGEGKSEGAMTTAEQLTATAVMPVARIIRMMLVTVFCGFFLTLFIFPSLIIPIDRDHNWFATIAILLYNCGDAIGRFSTSFKCVWPPRRALLYATFARFIFVLPFMLCIYQYIPGHVGPYIFSFLLGLTNCVGAMSMVYGPITPGLETAGQKLMAGQLMGISLLSGIAAASVLAMIVVVFLP
Protein: Homeobox protein Hox-D11 (Homeobox protein Hox-4F) (P31277)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-D10
- Homeobox protein Hox-D13
- Homeobox protein Hox-D9
- Sonic hedgehog protein
Sequence:
MNDFDECGQSAASMYLPGCAYYVAPSDFASKPSFLSQPSSCQMTFPYSSNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
Protein: Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Erythrocyte plasma membrane 50 kDa glycoprotein) (Rh50A) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (Rhesus blood group-associated ammonia channel) (Rhesus blood group-associated glycoprotein) (CD antigen CD241) (Q02094)
Organism: Homo sapiens (Human)
Function: Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the erythrocyte membrane. Seems to act in monovalent cation transport.
Subcellular location: Membrane {ECO:0000269|PubMed:15856280, ECO:0000269|PubMed:18931342, ECO:0000269|PubMed:22012326, ECO:0000269|PubMed:27247322}; Multi-pass membrane protein. Note=Localization at the plasma membrane is regulated by ANK1. {ECO:0000269|PubMed:27247322}.
Interaction partners:
- Glycophorin-B
- Glycophorin-A
- Leukocyte surface antigen CD47
- Blood group Rh
- Rh blood group D antigen
- Ankyrin-1
- Protein 4.2
- Band 3 anion transport protein
- Aquaporin-1
- Protein phosphatase 1 regulatory subunit 3A
Sequence:
MRFTFPLMAIVLEIAMIVLFGLFVEYETDQTVLEQLNITKPTDMGIFFELYPLFQDVHVMIFVGFGFLMTFLKKYGFSSVGINLLVAALGLQWGTIVQGILQSQGQKFNIGIKNMINADFSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIGASMTIHAFGAYFGLAVAGILYRSGLRKGHENEESAYYSDLFAMIGTLFLWMFWPSFNSAIAEPGDKQCRAIVNTYFSLAACVLTAFAFSSLVEHRGKLNMVHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFTTKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMGASNTSMAMQAAALGSSIGTAVVGGLMTGLILKLPLWGQPSDQNCYDDSVYWKVPKTR