wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40) (rpL40)] (P62987)
Organism: Homo sapiens (Human)
Function: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Subcellular location: [Ubiquitin]: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.; SUBCELLULAR LOCATION: [Large ribosomal subunit protein eL40]: Cytoplasm {ECO:0000269|PubMed:39048817, ECO:0000269|PubMed:39103523}.
Interaction partners:
- Small ribosomal subunit protein uS9
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS12
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein eL34
- Large ribosomal subunit protein eL15
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein uL29
Sequence:
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK
Protein: SibC (C0LTL7)
Organism: Streptosporangium sibiricum
Interaction partners:
Sequence:
MSATPPKAVIVGAGPVGCLLAVELRRRDFDVEIYEKCDADTVLRPGVGRSFNLTLTHRGLSVLHPWLRDRVYEIGSVLRQRIVHHTDGTLTRQPYGISDDQHLLSVPRRELQRILLAEARASGARMFFGHSCVGADAHRGEAMFVDPRGTVRHAAGDILIGCDGANSALRYELSKGGARMQVHQRYIAHGHVELTLTPEGSAALAPDGMHLWPRSDHFLQAQPNRDGSTTTTLFMPVGNEGGELRFRSLTGTEAVREHFEREYPDIAPHLPLAADEVIRARPALLKVVDCAPYNYGRAVLVGDSAHTIVPFFGQGINCSFEDADILCRLLDKYWRSGVDRHEAIRAAGAEFSEQRVAAGQAISQLSMDNLHELSKSIDDAGFHRRQRLERMLHEYRPAEFTQLYQLVAFTRTPYDEIIRRSRIDKLALDTLCELYDPDTEAETIISSYAEVRRGLDEHDTREPALALTATPAKGEH
Protein: CUB-like domain-containing protein (O02357)
Organism: Caenorhabditis elegans
Interaction partners:
- CUB-like domain-containing protein
- CUB-like domain-containing protein
- CUB-like domain-containing protein
- ShKT domain-containing protein
- Protein irg-1
- Mitogen-activated protein kinase pmk-1
- C-type lectin domain-containing protein
- C-type lectin domain-containing protein
- CUB-like domain-containing protein
- CUB-like domain-containing protein
Sequence:
MLSRSVVLLLATSTFVAAQFSCPLNTISKNNGMSGSIPPGAASMVQVPAGSTCTFKFDIPKGFALKIETTADYDISKRDSIKFDDFYITSPAEKKIEYAVRKTLPYNVVSKSGSLKFFATYTYVDISNYQQVIKATGTFFNTTLEANKFTTVRAANNDQVALKYGSRETGFHDETMYQTFVFDGNDFMNSEYLGRYTDLYHGPDYTAFSTSNTLTLLNLYRTPSDSLFISNDASAVKKYDQYKILVVSSANQISGLMYNFHDNADAWYTIICDGCNSINIKSLDFDTSYNGYLEVQELSPTQKLPPKFRFQAGNNQLPQLVSAPMTTFHTYKARVSFTVQGEN
Protein: Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2) (Q16827)
Organism: Homo sapiens (Human)
Function: Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
Sequence:
MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDGFHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Protein: Negative regulator of differentiation 1 (Multicopy suppressor of sporulation protein msa2) (Q09702)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Negative regulator of sexual differentiation. Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes until cells reach a critical level of starvation. RNA-binding protein that preferentially binds poly(U).
Interaction partners:
- Small ribosomal subunit protein RACK1
- Multicopy suppressor of sporulation protein msa1
- Negative regulator of sexual conjugation and meiosis
Sequence:
MSSSSPSSQSRLSVPGRTPHLPPLTIPHTVSAEGLATPNTPHALLPTGLLMGSPFVQSPTSYTSMHGLPFSTTQMAAAPAHPTTGYNVSRVTSPNVANFAPGYFPLPNNTTQPVKTVYVGNLPPNTPIDEILSCVRTGPIESAWILPEKNCAFISFLDPSHATAFFQDAALKRLTIRGTEVKVGWGKNSASNSSVLLAVQQSGACRNVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERNIAFVHFLNIAAAIKAVQELPLNPKWSKRRIYYGRDRCAVGLKQPAYFSKGQVGVVGGYPVMGYPPPSPVLQKPDLIMTGNRTVYIGNIHADTTIEEICNAVRGGLLHNIRYLQEKHICFVTFVDPVSAFRFFEMSNIHGLVIRNRRLKIGWGKHSGPLPSNIALAVAGGASRNIYIGNADDSLTIERLKEDFEEFGEIEYVNFFREKNCAFVNFTSLASAINAIDRIKQKKGYENYRISYGKDRCGNPPRTNSKSDVLSVSSDMSMPVDLVVPQQGISGFMPTNSNI
Protein: Non-structural 5A protein (O39474)
Organism: Hepacivirus hominis
Interaction partners:
Sequence:
MGSGSWLKDVWDWICTVLADLKTWLQSKLLPRLPGVPFLSCQRGYKGVWRGDGIMNTTCPCAAQITGHVKNGSMRIVGPKTCSNTWHGTFPTNAYTTGPCTPSPAPNYSRALWRVAAEEYVEVTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLRDEVVFQVGLNQFPVGSQLPCEPEPDVAVLTSMLTDPSHITAETAKRKLARGSPPSLASSSASQLSAPSLKATCTTRHDSPDADLIEANLLWRQEMGGNITRVESENKVVILDSFDPLHAEEDEKEVSVPAEILRKSKRFPPALPIWARPDYNPPLLEPWKDPDYVPPVVHGCPLPPNKAPPIPPPRRKRTVVLTESTVSSALAELATKTFGSSGSSAVDSGTASAPPDQSTDNGDTGSDVESYSSMPPLEGEPGDPDLSDGSWSTVSEEAGEDVVCCSMS
Protein: Phosphoprotein (Protein P) (Protein M1) (P16286)
Organism: Rabies virus (strain SAD B19) (RABV)
Function: Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body (By similarity).
Subcellular location: [Phosphoprotein]: Virion. Host cytoplasm {ECO:0000269|PubMed:36640307}.; SUBCELLULAR LOCATION: [Isoform P2]: Host cytoplasm {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform P3]: Host nucleus {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform P5]: Host nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MSKIFVNPSAIRAGLADLEMAEETVDLINRNIEDNQAHLQGEPIEVDNLPEDMGRLHLDDGKSPNHGEIAKVGEGKYREDFQMDEGEDPSFLFQSYLENVGVQIVRQMRSGERFLKIWSQTVEEIISYVAVNFPNPPGKSSEDKSTQTTGRELKKETTPTPSQRESQSSKARMAAQIASGPPALEWSATNEEDDLSVEAEIAHQIAESFSKKYKFPSRSSGILLYNFEQLKMNLDDIVKEAKNVPGVTRLAHDGSKLPLRCVLGWVALANSKKFQLLVESDKLSKIMQDDLNRYTSC
Protein: Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (O45321)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU365061}. Chromosome, telomere {ECO:0000256|RuleBase:RU365061}.
Interaction partners:
- DNA/RNA-binding domain-containing protein
- ATP-dependent DNA helicase II subunit 2
- WD_REPEATS_REGION domain-containing protein
- Ku domain-containing protein
- Putative H/ACA ribonucleoprotein complex subunit 4
- Protection of telomeres homolog 2
- Protection of telomeres homolog 1
- RuvB-like 2
- PIN domain-containing protein
- Double-strand telomeric DNA-binding proteins 2
Sequence:
MAPTIKSSLTTLHEEIRKYDKRRHWNTIIRKSAHLSLVRNIFKKKRRQKLNYRHMSTFLASSENISNIRDTVVLLEINKLSQSILSSRNIFELRKLKPTRKMVEIEHCFVSKNDTFVACSKLISMFHLEKYIGSTNCANILEWITKMLNNGGYHKMKPFVYKEAPFTRAFRASKVMKNVDPNVKRNIQTSIVNNLKSGVHWWALMALRQVMIPIVIKEERVLLWRDGYLNILTKEIKDFKQRYIVQKAPHFIRPNVATFKLSISRQKLRPLFKRKAIDKKTETMQWKRLNSMLSWCLERSGVYRHTIRDSCKKVSDFLKKNSQNSKIIGYTADVSKCFSTVNHDVLISIIDRLFSQEHDIYTVCGKGRNHGGFHKLIFCSAGTELNAHEALRRKMELKGVFNFEVCYREMSSSTTLYSVIRTTLSTYYYKRGPTSWRITKGVPQGHPISSNLAHMYLNNFEQKYWSNEKEDSRIVFCRYEDDFIFITTENSLFEKMMKPLSTGNNTHFLTANPKKFKKSERCGASQVLQWCGVKLDFQSGNCFIRRRCKDGVARQFLIKLQ
Protein: Putative F-box protein At3g10790 (Q9SG85)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEEVKGKRTISNTWKLVTRSQTDPFEGMPLHLKEKILMKLKAKIISTFILLSKSWSSIVLNKDFTNMYLIIKFFESLNRPRLLLAVDDREINMQFFHSCSREDPSSDHQTVGCYPDSYPRIWYDFSPPVRGLICCLNNSTKVVIGNPTTCQFETLPRVRTKIYQEIFPFFGYDHVKDEYKVLCMTISDEYYSRSGNIVSKEHKVFTLGCKQKKWRMIECTINHYLTPGTQGIFSNGVIYYFARVNDDQSLMCFVVGSEKFSVVELPRPAVEVLANYGEKIAVTNLLYASNDRLFVWILEDASKQEWSNFCVLVPSWVDI
Protein: Transcription initiation factor TFIID subunit 9 (RNA polymerase II TBP-associated factor subunit G) (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII31) (Transcription initiation factor TFIID 32 kDa subunit) (TAFII-32) (TAFII32) (Q5BKE0)
Organism: Rattus norvegicus (Rat)
Function: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF9 is also a component of the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TAF9 and its paralog TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. Essential for cell viability. May have a role in gene regulation associated with apoptosis.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPTVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKAPTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQAMSVSTKVGTPMSLTGQRFTVQMPASQSPAVKASIPATPAVQNVLINPSLIGSKNILITTNMVSQNTANESANALKRKREEEDDDDDDDDDDYDNL
Protein: Uncharacterized protein, isoform B (Q7KUK9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GH14967p
Sequence:
MLRLLLVHIITICVLITIVKCGVPIGTGGPSIILESKDALLTCVVSDNSSNNTVIWKKGDEILTAGTVRVTKDHRVRILHDENPKGKNLETGGEVWVLLIKTLKPNDSGAYICELNSDPVLRSIHILTVKELHSSTGGPGNSTDTSTAESSDVFLLPPPLDAQDNRSFWRPSQVPPLVTHDFTECCERANVSTQCMGFCNVHNILDGTTGIDPEACERDFPGIVRCMADGRNHVPCCVDKQIPDLCQDMCRGEYTPFTDKLKTRVSCVQHTLSGLQCILKGVQLIPSSPTFVTIENVSETSVTIGWTAPDKLADRVSGYTINLTTLHSFDEDELSGEIVHRTASDSPESISLYSVPTNQTQLTLSNLSPLTMYAVIVTATNEFGSSLPTERLRFFTHTSASAAESKAGTTDKQAMPQLPDTRQCCEDNGMTHRMCLDKMCDPQKTDQANLPDFMVCAPWSNITFNCLANNIDHTPCCRARGIPSACFPLCAGKLTSLDFSLFKCLRFMSEYNSCLFQGYGVLADPPSKLRTVAKTDSFVILDWNKPKRLADTVSTYHVKFRRLGVGDDYLTVEKRQPPLILEGLESDIYYEFYVVSINAYGKSEASPRLITRTLPAEPVQQTAARYNMTTCCQASGLLPQCAPLCSYNIRLSDIERLGPACRAQMPILARCAAGGRDHSPCCSRRGVINACMPLCRGVMPLALTTKSSSASAAAAATSSSSGATAATSASATSNSNAAGAPSSSSSSASSGTSSNVPDCLSYAGNILQCFEEGTQNIPGPPEDVHATFVNQSSVSLAWTQPDVDNSNSSSSGNASPGDMITGDELAAGAVDPANAGKDVPNAGDATSGTTGTEDIEFIVQYGKVNNMTMYETVAKLENELTTNETSIDLTNLDANALYRITVVTRGKFGTSLPASMLLLNTTDQQRTGEAWGAPSPPHSLTVVAHSATWMQLTWQPPEYAHPHERITYRVYHKAMRAEQFIKIETKLAWLRMNNLKPSSQHVLYVEAVGERGDSLPSETLVAWTDPALPAFVDPPTVHPADNIPEGGSMTILCLAFGNPAPTISLYVGGHLVRQDASRHMVTVIHNVSADMEHVSCYADNGYGVPMQATRRVNICYPPKIQAAGITVANIGDEIELRCTVDSKPAPKTIFWREKDGRVPVINGGNYFISVKANESRPSIYTMSLRISKLQANDVGDYFCHADNPFGATTTPVSVRIRNTPALNHNVSECCAAQNVSMACRSACSYYVDFDAIADRPECIVDFDKLMRCAADGSDHRSCCADEHVPRKCLNWCRGESVRSKEICSLQYARTIVGCFEKNRDRLPGPPENIVVSVVSDSEVNVRWDAPTKNPNAVDGYRIFYHEAAILPPTSSSSSGSPSSDSGSSMENPGMDTLAAMNNATSMGNSNNAMAALEIRRIDVKDTTISINGLKKDVLYELVVKAGNSYGASVLTDPIRFTLGEHHVTSATSSYSSAVGTISGIVASILAILLAAAAIVFYRRQRSSYGKSANGNVAFENPTYTRGLEQVQLPTVTSAITTQNGNHHGMSSSNNNGSSNSHSHGRNGIAATMTTSTTTTAPTAAAAASATSAGVALTGNRQHQQQQQQQQQQQQQHKSAADAAHHFHNPLSNTQCNEVNPTIYEELKLGQEGAGFKKLVP
Protein: Serine/arginine (SR)-type shuttling mRNA binding protein HRB1 (Hypothetical RNA-binding protein 1) (Polyadenylate-binding protein HRB1) (Protein TOM34) (P38922)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Binds to intron-containing transcripts and is involved in quality control for the export of spliced mRNAs from the nucleus. Binds to pre-mRNAs until splicing is completed or until faulty mRNAs are degraded. On correctly spliced mRNAs, GBP2 and HRB1 recruit MEX67 to allow nuclear export. On faulty mRNAs, GBP2 and HRB1 associate with the TRAMP complex that guides those pre-mRNAs to the exosome for degradation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14676199, ECO:0000269|PubMed:24452287, ECO:0000269|PubMed:9499403}. Nucleus {ECO:0000269|PubMed:14676199, ECO:0000269|PubMed:24452287, ECO:0000269|PubMed:9499403}. Nucleus {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:23222640}. Cytoplasm, P-body {ECO:0000269|PubMed:23222640}. Cytoplasm, Stress granule {ECO:0000269|PubMed:23222640}. Note=Shuttles between nucleus and cytoplasm (PubMed:9499403). Nuclear at steady state and its import is mediated by the karyopherin MTR10. Export is dependent on active transcription and the export of mRNAs in general. Depends on MFT1 and HPR1 for nuclear export (PubMed:14676199). {ECO:0000269|PubMed:14676199, ECO:0000269|PubMed:9499403}.
Interaction partners:
- THO complex subunit 2
- RNA annealing protein YRA1
- THO complex subunit THP2
- THO complex subunit HPR1
- mRNA export factor MEX67
- ATP-dependent RNA helicase SUB2
- Serine/arginine
- THO complex subunit MFT1
- Small ribosomal subunit protein RACK1
- Protein TEX1
Sequence:
MSDQERGSENNNRSRSRSRSPVRRRMSDDHGYERDNHLSRRSGNYNGRRKFADTYRGSRDRGEYRGGRERSDYRERERFNNRDNPRSRDRYDDRRRGRDVTGRYGNRRDDYPRSFRSRHNTRDDSRRGGFGSSGARGDYGPLLARELDSTYEEKVNRNYSNSIFVGNLTYDSTPEDLTEFFSQIGKVVRADIITSRGHHRGMGTVEFTNSDDVDRAIRQYDGAFFMDRKIFVRQDNPPPSNNIKERKALDRGELRHNRKTHEVIVKNLPASVNWQALKDIFKECGNVAHADVELDGDGVSTGSGTVSFYDIKDLHRAIEKYNGYSIEGNVLDVKSKESVHNHSDGDDVDIPMDDSPVNEEARKFTENVVGGGERNRLIYCSNLPFSTAKSDLYDLFETIGKVNNAELRYDSKGAPTGIAVVEYDNVDDADVCIERLNNYNYGGCDLDISYAKRL
Protein: RUN domain-containing protein 3A (A0A0G2JW67)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MEASFVQTTMALGLPSKKASSRNVIVERRNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDNRTTRRFYDSGAIMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYNKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLPDPPPPPRTGLIPGDHAPLAQGSKELTTALVNQWPSLSTLSRPEGASNSKLFRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIGSSEPN
Protein: Homeobox protein NOBOX (Homeodomain-containing protein OG-2) (Newborn ovary homeobox protein) (Oocyte-specific homeobox protein) (Q8VIH1)
Organism: Mus musculus (Mouse)
Function: Transcription factor which plays an essential role in postnatal follicle development. Binds preferentially to the DNA sequences 5'-TAATTG-3', 5'-TAGTTG-3' and 5'-TAATTA-3'. Directly regulates the transcription of POU5F1 and GDF9 during early folliculogenesis.
Subcellular location: Nucleus.
Interaction partners:
- Factor in the germline alpha
- Growth/differentiation factor 9
- Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
- Bone morphogenetic protein 15
- Zona pellucida sperm-binding protein 3
- Zona pellucida sperm-binding protein 1
- Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
- LIM/homeobox protein Lhx8
- Forkhead box protein L2
- Y-box-binding protein 2
Sequence:
MEPTEKLCKKMQGQEAGDKPRTAALETEGPLQDSALPIQDDQDKQSSLPRASLGKRPLSKTSEELMDAGTCRVHKAPTAAACGPQSEEEGCSPPERKAESLKPSISAVPGQATAGSLNSHEGDLKKESLEVTCQFRKKTRTLYRSDQLEELERIFQEDHYPDSDKRHEISQMVGVTPQRIMVWFQNRRAKWRKVEKLNEKETKNGPAAPSADSSQHRSAPELLDPMPTDLEPGPVPPENILDVFPEPPMLLTSEQTLTPFQNNEGAERVAVTPPLLSPPPIRRANLPLPLGPVQTPQVLPPMRDVPGSDSIYKDKAYVSWGTSIASPPTYSNLEDLGSQDYQASSQLGSFQLSQAPHLPLFPSLQSQFPYLPPFPYPIPSSMPFLPPEDSLFSFPFGFSGDSSQDYCPGPPPGQILLQPPAENMGTGPWSGHCLPEPPFPRPHYPQALGQPLGAEGYFPNLLPTPYALTMSKQSSLGLNGLLEGTRVETGSSLSKMSDEQTSSSLEQPALEEVRDKNKNSHAAGAKE
Protein: Tubulin beta-5 chain (Beta-5-tubulin) (Q6VAF7)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Classical arabinogalactan protein 5
- Tubulin-specific chaperone A
- Tubulin-specific chaperone A
Sequence:
MREILHIQGGQCGNQIGAKFWEVICDEHGVDNTGKYNGDSDLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLATPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTACAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESDMNDLVAEYQQYQDATADDEYEEGEEEEEEAA
Protein: Signal peptide peptidase (A3CWV0)
Organism: Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
- Cell division protein SepF
- Peptidase S26B, signal peptidase
- PRC-barrel domain protein
- PRC-barrel domain protein
- Uncharacterized protein
- Putative phosphoserine phosphatase
- KEOPS complex Cgi121-like subunit
Sequence:
MQIRDWLPLLGMPLMLLFVQIIAIVLVMPMQAAGLVAFEDPESVANPLIFIGMLLAFTLVLLVLLRTGGRRFIAAFIGFALFMTFLYIFGALSLLALGPTTAAAAGTLIGAVAVTALLYLYPEWYVIDILGVLISAGVASIFGISLAVLPVLVLLVLLAVYDAISVYRTKHMITLAEGVLETKAPIMVVVPKRADYSFRKEGLNISEGEERGAFVMGMGDLIMPSILVASSHVFVDAPAVLWTLSAPTLGAMVGSLVGLAVLLYFVNKGNPQAGLPPLNGGAILGFLVGAALAGSFSWLPF
Protein: Protein HID1 (Q7Z135)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGAQGSRVDFKQVVLDVTSKPGKDDETFWDQAWWPDSVNEIFAMISGEDIRKLRDESPKNLATLVYKTVEKLQFSRNHPATIDQKKTINAIRLLTRIVPYLLEDAEWRGYFWSPIPHGDAAKPLAAVLLETLSDLLFCPEFTITHANGQKIDDLSTIDSCEYIWEAGVGSGNKPPMVALHYQNRTEILKLLLTCFAELIYAPVSDETRLRWVIHFTSVTNPHVLPIFTSLLNIVCAYDPVGYGLPYNYLLFNDSREPLVEIALQVLIVCLDKETQPNTDDSGYKDNYFINYLSRIHREEDFDFMLKGITRLLSNPIHSSSSYLPNSTKRVNFHQELLVLLWKCCEINQKFMFYVLKTSDVLDILVPILYHISDARNDSGRVGLIHMGVFIILLLSGERNFGVRLNKPYTAKANINVQTFTGTHADLLILVIHKLITTGNYRLQTLFDCFLTIMVNVSPYMKSLSMVAANKLVHLVEAFSTPWFLFSSPTNPQLVFSLLEVFNNVIQYQFDGNSNLIYTIIRKRNVFYQLSNLSTDAASIAKTLSGRKSKSANRDEMVDQLKSPTSTAPPEIPAADAPAAQTLGGVSTTTGLAATPALASMTGNVGNWEERPESSQDNEWIATQEWADAWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPIVIRRYQTNIGTNHWFRIYMWGVIYLK
Protein: ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase) (P0DOB5)
Organism: Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Function: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00339}.
Interaction partners:
Sequence:
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGIEVYGINHGYAGMVAGDIFPLTSASVGDKIGRGGTFLYSARYPEFAQVEGQLAGIEQLKKFGIEGVVVIGGDGSYHGAMRLTEHGFPAVGLPGTIDNDIVGTDFTIGFDTAVSTVVDALDKIRDTSSSHNRTFVVEVMGRNAGDIALNAGIAAGADDICIPEKEFKFENVVNNINKGYEKGKNHHIIVLAEGVMTGEEFATKLKEAGYKGDLRVSVLGHIQRGGSPTARDRVLASRMGARAVELLRDGIGGVAVGIRNEELVESPILGTAEEGALFSLTTEGGIKVNNPHKAGLELYRLNSALNNLNLN
Protein: RING-type domain-containing protein (Q387D3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSTSIEGDNCGICFTSIHPQCNPRGKLNSCGHIFCAYCIKKWAESTNVCPHCKARFTTITVSNTKGKNEVKKVRKRNYKLWELSDSESEGEGGEALALPRGSVRCGVCGEGDNAIRMIFCDRSQCDYTVHLDCVGMSDRPSEFFCSECRAMFGEGETSTCPPPNVGKDRSCNPTEYNGSSSSPSSNVCAPAPSPCTTTARKISVPPPAFLREAMERSAGKRLRDANVENRSETPVMPRRNANDWSPEGGYVNVDNGTINHAAQTAMQQYLQRMEQRAHREKLQCAHRPAQRQGGGDCLRQNTQLRLDRRCAQVRSAANAAEMEALLNPITRQREEERLARQLAKDLMPVLRRNQYLKDNRLVLDSDGCVVMNPPPSELEASGREAELYSQAMVEGRRMAQQRISAKVASARLRKEQLLMIQAEREALALNQLAMMIASRRTGGGDPKVD
Protein: RNA-binding protein YhbY (P0AGK4)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16980477, ECO:0000269|PubMed:33639093}. Note=Comigrates with the pre-50S ribosomal subunit (PubMed:16980477, PubMed:33639093). {ECO:0000269|PubMed:16980477, ECO:0000269|PubMed:33639093}.
Interaction partners:
- Dual-action ribosomal maturation protein DarP
- Ribosomal silencing factor RsfS
- Nicotinate-nucleotide adenylyltransferase
- Ribosomal RNA large subunit methyltransferase E
- Putative RNA-binding protein YbcJ
Sequence:
MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHHELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR
Protein: Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3) (Q6P5Z2)
Organism: Homo sapiens (Human)
Function: Contributes to invasiveness in malignant prostate cancer.
Subcellular location: Nucleus {ECO:0000269|PubMed:10441506}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:10441506}. Note=Nuclear and perinuclear Golgi region.
Interaction partners:
- Rho GTPase-activating protein 10
- Rho GTPase-activating protein 26
- 3-phosphoinositide-dependent protein kinase 1
- Serine/threonine-protein kinase N1
- Rho-related GTP-binding protein RhoC
- Serine/threonine-protein kinase N2
- Transforming protein RhoA
- Ras-related C3 botulinum toxin substrate 1
- Rho-related GTP-binding protein RhoB
Sequence:
MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSSNRRLEQLHGELRELHARILLPGPGPGPAEPVASGPRPWAEQLRARHLEALRRQLHVELKVKQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLAEELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLLEQLPPAHPLRSRVTRELRAAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSPAAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVIPLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVIERRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMNLLPPCSSPSTISPPKGCPRTPTTLREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTSEETPRTKRPHMEPRTRRGPSPPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP