wanglab/gogpt-training-data huggingface dataset:
Protein: GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O) (Q8TEQ8)
Organism: Homo sapiens (Human)
Function: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9JJI6}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- GPI-anchor transamidase component PIGT
- GPI-anchor transamidase
- GPI alpha-1,2-mannosyltransferase 3
- GPI-anchor transamidase component GPAA1
- GPI-anchor transamidase component PIGS
- GPI-anchor transamidase component PIGU
- GPI ethanolamine phosphate transferase, stabilizing subunit
- GPI alpha-1,6-mannosyltransferase 2
- N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
- Acyltransferase PGAP2
Sequence:
MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEATLPTVIAELQQFLRGARAMCIESWARFSLVRMAGGTALLAASCFICLLASQWAISPGFPFCPLLLTPVAWGLVGAIAYAGLLGTIELKLDLVLLGAVAAVSSFLPFLWKAWAGWGSKRPLATLFPIPGPVLLLLLFRLAVFFSDSFVVAEARATPFLLGSFILLLVVQLHWEGQLLPPKLLTMPRLGTSATTNPPRHNGAYALRLGIGLLLCTRLAGLFHRCPEETPVCHSSPWLSPLASMVGGRAKNLWYGACVAALVALLAAVRLWLRRYGNLKSPEPPMLFVRWGLPLMALGTAAYWALASGADEAPPRLRVLVSGASMVLPRAVAGLAASGLALLLWKPVTVLVKAGAGAPRTRTVLTPFSGPPTSQADLDYVVPQIYRHMQEEFRGRLERTKSQGPLTVAAYQLGSVYSAAMVTALTLLAFPLLLLHAERISLVFLLLFLQSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR
Protein: Uncharacterized protein (Q387G7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Paraflagellar rod component
- Uncharacterized protein
Sequence:
MGHAFCLPEKRGNDARPYFGAPISDLIVCEQNEVQKSTNCILGVPLILQDVVFYWNAQSNTKGENGKADVSPNSSWVDEVEQTFNNFVRKRKLLTSSASAVKAPKKNAKKTNKHEKRLFQKPFEALTSKTTLHAQHFMAIITLFLRKLPEPLLPVPVARKMEDILTSGPLTPTAKLRAIGKVFRETYSLANPREYASFQYLRQVLHQHHAELKTNEVEALVRAMLRDHRAPVEEYLIELLWPTADGEGKMKAGTAEADSTTPADERDNAVDGEAKALPQHLHDSNSETDSSPPKVVDRPTDVVKAGKQKKEDVANDECVRKNAAPPPAEKDCKVEEDAAGAQSQREDMSPHSSRTSDTHILEVEEHGDEVEAFHHVNGEHCGDVDGLDHDKSVECRVTQVGSESCAGPGEGTVDEEGPLQDVVESPTVSDGASCVDRRGGLAHAITDASETEVCDVVQRGSREDRGCVELDNVVDTPDGGHYSTAAAKGKLRQANRPVHRDERLSASGDAASQIGGPLTATTASLTNNQFAPRKPRDKPRTGRSRKNLRVLTERHPQQVALLRAKQLFLAGGAGATELPSLPNQPASSPPGGELDDGDCCVSSVDPSSTRIAGGHTGVQYTAAEEQPLSPEGHLQSAAVFSNTDDNQDTRKCGPDNEWMAAQHLQLAFVQPLMEQMAQLRMQCDALSQQQLRSATEGETLQLVSNDIKLVKEALCQLTQSHAETVGDLLKLHGELKKLAKRETFELEKRHYCEEDLEARKTALEVLQRCTKLETQQYEDQQKVKSLTTKVRELTAKVDRSEKENLDLKMKLATAQRQTTLMREKLMSSGREGRSV
Protein: Ubiquitin-like modifier-activating enzyme atg7 (ATG12-activating enzyme E1 atg7) (Autophagy-related protein 7) (Q86CR9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the atg8 association to autophagosomes membranes (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium.
Subcellular location: Cytoplasm {ECO:0000250}. Preautophagosomal structure {ECO:0000250}.
Interaction partners:
- Ubiquitin-like protein atg12
- Autophagy-related protein 3
- Autophagy-related protein 8
- Autophagy-related protein 8-like protein DDB_G0290491
- Autophagy protein 5
- Autophagy-related protein 18
- Ubiquitin-like-conjugating enzyme ATG10
- Autophagy-related protein 9
- Probable serine/threonine-protein kinase vps15
- Serine/threonine-protein kinase atg1
Sequence:
MTNTLQFKEFSSFVNISFWHELSNKKLDELKLSEESIPLNGHYTFSPSQQLDPFLCLEFNAFLRNNVTNSTENQYVLPPRSYLSHGTLYNYNTVDDFKQSPKIKLFNDASKRIWNDINNGNIDKDTSLLNRFILLTYADIKNHQFYYMFGIPALLPSQPIQQFTEKPESINIESLKSFSNQILPQYFCLKQQQQESSTTTTTSFELIGSIEEKGNQYLNECLENDLIPLVGFCDPCSLPLNPGWPLRNFLIYLSIKYPMLKKIKVLCYRGNGSTSNSILLSLELPSMGEQLIKKQQEEDAGEWSGKSVGWEKDSNGKIAPRFVSLASTMDPLKLAEQSVDLNLKLMRWRVMPSLELEKIKTTSCLLLGSGTLGCNVARSLMSWGVRNITFVDSSKVSYSNPVRQSLFTFADCSPKAKEKSIAAADALKKIFPAINANAHVFSIPMPGHSVPQSEYQSIRNTIELLENLIKQHDVIYLLTDSRESRWLPTMLSRAHGKLCINAALGFDSYLVIRHGIKDQCQNELNPSISSKLGYQGSDLGCYFCNDVIAPTDTLKDRTLDQMCTVTRPGLSMMASSIAVELLISTIHHPYGGRAKGETETDVYVQGSTPLGIIPHQLRGFISHYQTLPLFSNPYKHCTACSDYIIDEYNSKGFDFIINVMNDSSCLTKICGIDDLKNTEVNIDWDIDISDDDDDNNNNNNKEKNDDF
Protein: Cytokine-dependent hematopoietic cell linker (Mast cell immunoreceptor signal transducer) (Q9QZE2)
Organism: Mus musculus (Mouse)
Function: An adapter protein which plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Together with FGR, it acts as a negative regulator of natural killer cell-activating receptors and inhibits interferon-gamma production. Acts as a positive regulator of both T-cell receptor and natural killer T (NKT) cell receptor signaling in CD4-positive NKT cells. Together with MAP4K1, it enhances CD3-triggered activation of T-cells and subsequent IL2 production. May be involved in tumor necrosis factor induced cell death by promoting reactive oxidative species generation, and MLKL oligomerization, ultimately leading to necrosis. Involved in phosphorylation of LAT. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q7Z7G1}.
Interaction partners:
Sequence:
MTSQGNKRTTKEGFGDLRFQNVSLLKNRSWPSLSSAKGRCRAVLEPLPDHRRNLAGVPGGEKCNSNNDYEDPEFQLLKAWPSMKILPARPIQESEYADTRYFQDTMEAPLLLPPKASVSTERQTRDVRMTHLEEVDKPTFKDVRSQRFKGFKYTKINKTPLPPPRPAITLPKKYQPLPPAPPEESSAYFAPKPTFPEVQRGPRQRSAKDFSRVLGAEEESHHQTKPESSCPSSNQNTQKSPPAIASSSYMPGKHSIQARDHTGSMQHCPAQRCQAAASHSPRMLPYENTNSEKPDPTKPDEKDVWQNEWYIGEYSRQAVEDVLMKENKDGTFLVRDCSTKSKAEPYVLVVFYGNKVYNVKIRFLESNQQFALGTGLRGNEMFDSVEDIIEHYTYFPILLIDGKDKAARRKQCYLTQPLPLARLLLTQYSSQALHE
Protein: Spermine oxidase (A0A8I6AJG4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGRRIPKDVVEEFSDLYNEPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP
Protein: sn-2 acyl-lipid omega-3 desaturase (ferredoxin), chloroplastic (EC 1.14.19.35) (Omega-3 fatty acid desaturase 7, chloroplastic) (P46310)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000269|PubMed:12766230}; Multi-pass membrane protein {ECO:0000269|PubMed:12766230}.
Interaction partners:
- Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic
- Stearoyl-[acyl-carrier-protein] 9-desaturase 7, chloroplastic
- Fatty acid desaturase 4, chloroplastic
- Glycerol-3-phosphate acyltransferase, chloroplastic
- Oleoyl-acyl carrier protein thioesterase 1, chloroplastic
- Delta-9 acyl-lipid desaturase 2
- Monogalactosyldiacylglycerol synthase 1, chloroplastic
- Phospholipid:diacylglycerol acyltransferase 1
- Palmitoyl-acyl carrier protein thioesterase, chloroplastic
- Beta-ketoacyl-[acyl-carrier-protein] synthase III, chloroplastic
Sequence:
MANLVLSECGIRPLPRIYTTPRSNFLSNNNKFRPSLSSSSYKTSSSPLSFGLNSRDGFTRNWALNVSTPLTTPIFEESPLEEDNKQRFDPGAPPPFNLADIRAAIPKHCWVKNPWKSLSYVVRDVAIVFALAAGAAYLNNWIVWPLYWLAQGTMFWALFVLGHDCGHGSFSNDPKLNSVVGHLLHSSILVPYHGWRISHRTHHQNHGHVENDESWHPMSEKIYNTLDKPTRFFRFTLPLVMLAYPFYLWARSPGKKGSHYHPDSDLFLPKERKDVLTSTACWTAMAALLVCLNFTIGPIQMLKLYGIPYWINVMWLDFVTYLHHHGHEDKLPWYRGKEWSYLRGGLTTLDRDYGLINNIHHDIGTHVIHHLFPQIPHYHLVEATEAAKPVLGKYYREPDKSGPLPLHLLEILAKSIKEDHYVSDEGEVVYYKADPNLYGEVKVRAD
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (A0A8J8XJJ2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
LIHAVPFPPTRRLTLKEVFENGKPKMDVLKNHLVKEGRVEEDVALKIINDGAAILKQEKTMLEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSELVYEACMHTFDCLPLAALLNQQFLCVHGGMSPEITCLDDIRKLDRFAEPPAFGPVCDLLWSDPLEDYGSEKTLEHYTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDEEMSLVEEEDHYISSCPKGATSVRKEVIRNKIRAIGKMARVFTVLREESENVLILKGLTPTGTLPLGVLSGGKQTIETAKLQAAEEREAIRGFTIAHRIRSFEEARGLDRINERMPPRKEASYHHDAGKTHPHPSKRSDHGKKAL
Protein: Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A) (Q96JJ3)
Organism: Homo sapiens (Human)
Function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20679435}. Cytoplasm, cytosol {ECO:0000269|PubMed:20679435}. Membrane {ECO:0000269|PubMed:20679435}.
Interaction partners:
- Rho-related GTP-binding protein RhoG
- Dedicator of cytokinesis protein 1
- Adapter molecule crk
- Adhesion G protein-coupled receptor B1
- WD repeat-containing protein 35
- Engulfment and cell motility protein 1
- Engulfment and cell motility protein 3
- Ras-related C3 botulinum toxin substrate 2
- Dedicator of cytokinesis protein 4
- Crk-like protein
Sequence:
MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG
Protein: Cleavage stimulating factor 64 (AtCstF-64) (AtCstF64) (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (Protein ENHANCED SILENCING PHENOTYPE 1) (Protein SUPPRESSORS OF OVEREXPRESSED FCA 19) (SOF19) (Q9M9G6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: One of the multiple factors required for polyadenylation and 3'-end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3' non-coding region. Required for the targeted 3' processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P33240}.
Interaction partners:
- 30-kDa cleavage and polyadenylation specificity factor 30
- FIP1[III]-like protein
- Cleavage and polyadenylation specificity factor subunit 2
- Symplekin
- FIP1[V]-like protein
- Polyadenylate-binding protein 3
- Cleavage stimulation factor subunit 50
- HEAT repeat-containing protein
- Cleavage stimulation factor subunit 77
- Cleavage and polyadenylation specificity factor subunit 1
Sequence:
MASSSSQRRCVFVGNIPYDATEEQLREICGEVGPVVSFRLVTDRETGKPKGYGFCEYKDEETALSARRNLQSYEINGRQLRVDFAENDKGTDKTRDQSQGGPGLPSTTTVTESQKQIGGPVDSNMHQPVGLHLATTAASVIAGALGGPQVGSQFTQSNLQVPASDPLALHLAKMSRSQLTEIISSIKLMATQNKEHARQLLVSRPQLLKAVFLAQVMLGIVSPQVLQSPNIVQAPSHMTGSSIQDAQLSGQNLLPPLAQRSQQLSRAPHSQYPVQQSSKQPFSQIPQLVAQPGPSSVNPPPRSQVKVENAPFQRQQVVPASTNIGYSSQNSVPNNAIQPSQVPHQALPNSVMQQGGQTVSLNFGKRINEGPPHQSMNRPSKMMKVEDRRTTSLPGGHVSNSMLPNQAQAPQTHISPDVQSTLLQQVMNLTPEQLRLLTPEQQQEVLKLQQALKQDHMMQPS
Protein: DNA gyrase subunit B (EC 5.6.2.2) (A0QNE0)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01898}.
Interaction partners:
- DNA gyrase subunit A
- Topoisomerase subunit TopoM
- Pentapeptide repeat protein MfpA
- DNA-directed RNA polymerase subunit beta
- Protein RecA
- DNA-directed RNA polymerase subunit beta'
- Beta sliding clamp
- DNA replication and repair protein RecF
- DNA topoisomerase
- DNA-directed RNA polymerase subunit alpha
Sequence:
MAAQKNNAPKEYGADSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDGRGIPVEMHATGMPTIDVVMTQLHAGGKFDGETYAVSGGLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKLKQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERVTAEEVVDDVVKDTAEAPKTADEKAAEATGPSKVKHRVFHYPGGLVDYVKHINRTKTPIQQSIIDFDGKGPGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRAALTSVVNRYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVAEPQFEGQTKTKLGNTEVKSFVQKICNEQLQHWFEANPAEAKTVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPSKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQSIITALGTGIHDEFDISKLRYHKIVLMADADVDGQHISTLLLTLLFRFMKPLVENGHIFLAQPPLYKLKWQRSEPEFAYSDRERDGLLEAGRAAGKKINVDDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVEARRSFITRNAKDVRFLDV
Protein: 12-oxophytodienoate reductase 3 (EC 1.3.1.42) (12-oxophytodienoate-10,11-reductase 3) (AtOPR3) (OPDA-reductase 3) (Protein DELAYED DEHISCENCE 1) [Cleaved into: 12-oxophytodienoate reductase 3, N-terminally processed] (Q9FUP0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. Required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program. In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).
Subcellular location: Peroxisome {ECO:0000269|PubMed:12445129}.
Interaction partners:
- Allene oxide cyclase 3, chloroplastic
- Allene oxide cyclase 2, chloroplastic
- Allene oxide cyclase 1, chloroplastic
- Allene oxide cyclase 4, chloroplastic
- Peroxisomal OPC-8:0-CoA ligase 1
- Lipoxygenase 3, chloroplastic
- Allene oxide synthase, chloroplastic
- Lipoxygenase 4, chloroplastic
- Lipoxygenase 2, chloroplastic
- Transcription factor MYC2
Sequence:
MTAAQGNSNETLFSSYKMGRFDLSHRVVLAPMTRCRALNGVPNAALAEYYAQRTTPGGFLISEGTMVSPGSAGFPHVPGIYSDEQVEAWKQVVEAVHAKGGFIFCQLWHVGRASHAVYQPNGGSPISSTNKPISENRWRVLLPDGSHVKYPKPRALEASEIPRVVEDYCLSALNAIRAGFDGIEIHGAHGYLIDQFLKDGINDRTDQYGGSIANRCRFLKQVVEGVVSAIGASKVGVRVSPAIDHLDATDSDPLSLGLAVVGMLNKLQGVNGSKLAYLHVTQPRYHAYGQTESGRQGSDEEEAKLMKSLRMAYNGTFMSSGGFNKELGMQAVQQGDADLVSYGRLFIANPDLVSRFKIDGELNKYNRKTFYTQDPVVGYTDYPFLAPFSRL
Protein: Meiotic PUF family protein 1 (Q10238)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: RNA-binding protein essential for meiotic progression.
Interaction partners:
- mRNA export factor crp79
- Meiotically up-regulated gene 103 protein
- Rsm22-cox11 tandem protein 1
- Meiotically up-regulated gene 60 protein
- Meiotically up-regulated gene 28 protein
- Meiotically up-regulated gene 110 protein
- Meiotic expression up-regulated protein 6
- Uncharacterized ribonuclease C609.01
- RNA-binding protein mde7
Sequence:
MQRDEERPIDFGMSLELPKTPNDVNYVKKLITQILYLQTLVSEQQKKIESSTLEVQKKKDQIRELERIYEMNPKSFLTLRRTPALKLLPETLSVELSNEVNLTSSTTSSCVKPSPYLTNCNLKNKDTFPVSKNNCSLSSGIFTNSNGTNNCFSTHPKSLDDAKDNVVPKKLNDTDQFPLWSKNETIDPIDLGYSFISPFSMSFASKGNEILDPGESTNKNLFYEFPNGTTEPFEKNSVHSGKETLQYSATISKWKAMIEQIIFQNDQAASLSLQQQLKNEDIEDNINLINTILPFSVTLMKNKFGNFLIQKCFEYSTEAQLQSFSYFLKKHVKELSIDAFGSHVLQKSLEIYPERFTNNLIEELIECLPATLMQRHSCHVWQKFFETRRKSLVDGIFDHFNKKMQGKWLQVSVSEMGSLVVQTIFENCKEKDKRTCLDEIINNMDQIICGQWGNWVIQHIIEHGSEPDKQRILNSLLKEVESYSTNRYASKVVERALRVCHVTFFDRYVKEITTPQNELPTIFLQEIASNQYGNYIVQYLLQVATPSQINLMAEHLKKHMVSLRGHKYGQRIAALVEKSKS
Protein: Inhibitor of glycogen debranching 1 (P43598)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as an inhibitor of GDB1, enhancing the ability of cells to store glucose as glycogen.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Glycogen debranching enzyme
- 1,4-alpha-glucan-branching enzyme
- Translation machinery-associated protein 10
- Respiratory growth induced protein 1
- WD repeat-containing protein YPL247C
- Glycogen [starch] synthase isoform 1
- Phosphoglucomutase 2
- Inactive diphosphatase DCS2
- 6-phosphogluconolactonase 4
Sequence:
MTDPHLNTPQVSTSPTFERSQDFLNIDEPPCAQETPSVSTFNLPGPSAPAQSVDKPVPMIRRRSTNYMDALNSREQARERESSIGEHAPGAERRSSGPMDFQNTIHNMQYRTTNDSDLSHAGVDMGDSISHTPICSRAGNRPIFKNSYLDNNSNGNSARVPHGSPPQLGTRRKSSFKYEDFKKDIYNQLHMFGEK
Protein: F-box protein At5g52880 (Q9FLX3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F-box/kelch-repeat protein At3g24760
- F-box/kelch-repeat protein At2g24250
- F-box/LRR-repeat protein At1g67190
- F-box/kelch-repeat protein At1g64840
- Putative F-box protein At1g47730
- F-box protein At4g27050
- F-box protein At1g30790
- F-box/kelch-repeat protein At3g04660
- F-box/LRR-repeat protein At3g03360
- F-box protein SKIP19
Sequence:
MKRYQNLKVGEAFSKNRIYPFACNELSSILNLAYSLSPKNVKALIFQDTLSAFRLLPDINTSAAVSAANLLLKSVEAVLPKQKKNLAIVEFKQAKVALKRRSKNREEEDIDIPSLPQDILIHIFSFLEISSLVSSAQVSRSWNQATHENSLWQSQFDLHFNHKVLIRMQSDIDWREAFKKAYIAANSSEALRSGRGYCSYCDSIVWHENLRCLNKQCRLKSGNKPLDLITTHQVVNYLLGIESSDDESESDDEAFPGRLWKLSYVPDYL
Protein: Pilotin OutS (Lipoprotein OutS) (Q01567)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Function: Out proteins are required for the translocation of pectate lyases and cellulases across the outer membrane.
Subcellular location: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
- Secretin OutD
Sequence:
MHVSSLKVVLFGVCCLSLAACQTPAPVKNTASRSAASVPANEQISQLASLVAASKYLRVQCERSDLPDDGTILKTAVNVAVQKGWDTGRYQSLPQLSENLYQGLLKDGTPKATQCSSFNRTMTPFLDAMRTVR
Protein: Amine oxidase (EC 1.4.3.-) (G1T7Z9)
Organism: Oryctolagus cuniculus (Rabbit)
Interaction partners:
- Histamine N-methyltransferase
- Amine oxidase
- Histidine decarboxylase
- aldehyde dehydrogenase
- Aldehyde dehydrogenase
- 4-trimethylaminobutyraldehyde dehydrogenase
- aldehyde dehydrogenase
- Antizyme inhibitor 2
- Ornithine decarboxylase
- Aromatic-L-amino-acid decarboxylase
Sequence:
MGREKLALGWTTVAAVLLVLHMASAEPSPQTLSSKAGVFADLSSQELKAVHSFLWSRKELGLQPSRAPTMAKNSVFLIEMLLPKKHHVLKFLDKGEKRPVREARAVIFFGAQEHPNVTEFAVGPLPRPYYMRALSPRPARRPSWASRPISAAEYTLLHQVVQEATKPLHQFFIDTTGFSYQDCHNRCLTFTDVAPRGLASGQRRSWLILQRSVEGFFLHPTGLELLVDHGSTNAQDWTVEQVWYNGKFYRSPEELAQKYADGEVDVVILEGPLPSGQGAESMEEPPLFSSYKPRGDFPTPINVDGPRLVQPQGPRYKLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERVAYEVSVQEAVALYGGHTPAGMQTKYIDVGWGLGTVTHELAPGIDCPETATFLDTFHYYDADEPVRYPRALCLFEMPTGVPLRRHFDSNFSGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVLEAKMHATGYVHATFYTPEGLHYGSRLHTHLMGNLHTHLVHYRIDLDVAGTKNSFQTLQMKLENITNPWSPSHHLVQPTLKETQYLRERQAAFRFGRTLPKYLLFASPKENPWGHKRSYRLQIHSMADQVLPPGWQEERAVTWARYPLAVTKYRESEQCSSSIYNQNDPWDPPVVFEEFLRNNENIEHEDLVAWVTVGFLHIPHSEDIPNTSTPGNSVGFLLRPFNFFPEDPSVASKDTVIVWPRAEGPNHVQRWIPEDQDCLMPPPFSFNGTYRPV
Protein: Collectin-11 (Collectin kidney protein 1) (CL-K1) (Q9BWP8)
Organism: Homo sapiens (Human)
Function: Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis.
Subcellular location: Secreted {ECO:0000269|PubMed:25912189}.
Interaction partners:
- Collectin-10
- MBL associated serine protease 1
- Mannan-binding lectin serine protease 2
- Ficolin-3
- Mannose-binding protein C
- Ficolin-1
- Ficolin-2
- C-type lectin domain family 12 member A
- Complement C1s subcomponent
- Complement C1r subcomponent
Sequence:
MRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYFMCEFDKENM
Protein: Mitogen-activated protein kinase (EC 2.7.11.24) (Q6FPF2)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- mitogen-activated protein kinase kinase
- protein-tyrosine-phosphatase
- Transcription factor
- Candida glabrata strain CBS138 chromosome L complete sequence
- Candida glabrata strain CBS138 chromosome I complete sequence
- Candida glabrata strain CBS138 chromosome H complete sequence
- Candida glabrata strain CBS138 chromosome M complete sequence
- Candida glabrata strain CBS138 chromosome K complete sequence
- protein-tyrosine-phosphatase
- Mitochondrial import inner membrane translocase subunit
Sequence:
MGKKIVFNISSDFQLKSLLGEGAYGVVCSAVHKPTGEIVAIKKIVPFDKPLFALRTLREIKILRRFQHENIISIFDIQKPESFEKFNEVYIIQELMQTDLHRVIATQTLTDDHIQYFIYQTLRAIKTLHGSNVIHRDLKPSNILINSNCDLKVCDFGLARIIDSGENGDNEVDKIGMTEYVATRWYRAPEVMLTNAKYSRAMDIWSCGCILGELFLKRPLFPGKDYRHQLLLIFGLIGTPDSSDKSMECIESRRARQYIASLQKYPPVRPLQKAFPGVNPVGVDLLSRMLVFDPRERISADDALAHPYLSTYHVPEDEPAGEPIPPDFFQFDQYKEVLTTKDLKKLLWNEIFHEQAT
Protein: Large ribosomal subunit protein bL20c (50S ribosomal protein L20, chloroplastic) (P0C447)
Organism: Oryza sativa (Rice)
Function: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).
Subcellular location: Plastid, chloroplast.
Interaction partners:
Sequence:
MTRVPRGYIARRRRAKMRSFASNFRGAHLRLNRMITQQVRRAFVSSHRDRVRQKRDFRRLWISRINAATRIHKVFDNYSKLIHNLYKKELILNRKILAQVAVLNSNNLYTISNKIKIIN