wanglab/gogpt-training-data huggingface dataset:
Protein: FA complementation group D2 (Fancd2 protein) (Fanconi anemia group D2 protein isoform X1) (B3DJT4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- FA complementation group I
- FA complementation group G.
- BRCA2 DNA repair-associated.
- FA complementation group L.
- Fanconi anemia, complementation group E.
- FA complementation group M.
- FA complementation group F.
- Ubiquitin-conjugating enzyme E2 T
- Fanconi-associated nuclease 1
- FA core complex-associated protein 24.
Sequence:
MMRKKKRSSVTVDEDPTLDVSKAKKSKSSGRSTKSSVQDSCQDSVFVQFLKESGVTLTPGSTANEIAVDQVIFQKRLQQRLRKSPRFPNIIQEFISALETYIEDPERFRNCLLPCVPAPTSQQDTNSSSYQESLVRLLLGIEMLQTLVINTLFEKLPEFMFEGASEDGLNVPRLIVNQLKWLDRIVDGKDLSSKLMQMVSVAPVEIQRDIITSLPEILEDSQHGDMAKELNGLLQQNTQLAVPILDALSSLNLSSTLLSEVREAVMGTLSAVQLEDLPVVVKFVLHSISASDANEVVCDLRKKLELEQCVLPAVLQASQSRMKNKTVSRSSSVPSCSSGQDSVALILDVIKSAIRFQKTISEAWLKAIENIDESEDHKVVDLLVLFILHSTNANHSRRGAERVLKVKVRKGLIQESLLQKTFKGHAQVMRGYFPSILALAQGLLRSPDCCVVPFGGHMYKQAFTAFDSYCQQEVVGSLVTHACSGVSGEVDVALELLCELVSQKPAEMSQFTVFVKGILDYMDNLTSQQIRRLFHLLSRLAFGQEQHGGHIQDDMHIVIRKQLSSTVPKYKRIGIIGAVMMVGSMGACRNKHDGSQGGTLPKETNRQVMALLELVRSCSESSPEAAALCYDELANLLQTCKLDPLVQAWIGKSVLEDFQDDFVVDLGPDISGAFMFPTSVLYNLDEEESEGGIAVNLLPLMALDQQHKTDTSQPAGVKRERRVSPLCLSPFFRLLRLCEEVQHEGDLEEIDALLGCPLILTDMEVVEKVDSLSKSEREFLCSLLFHTINWFREVVNAFCRQNDPEMKMKVVTRIQNITYLQSLLQTCLAATPGYIPPQANFDGESADVMIPSSSVVQQKKGKKESSGRKRKASASKNSSGDKSQLEGAADAEESQPDPPEKESEKEKEKDGKSGVSLSSYWPFFRELDVEALSVLQCGLLSRTLLDTELHSKLREEVQLGPAELLFLLEDMWRKLDFSLTSAPAKKAPFLKGKMDKAVGFAHLQQKNAKEIATCCSDLLPTLCTHLENCHNHFQTLLTENQGVVDAPNVDVKENQLMCSAYQLLLQVLHTMFSWSGFSIPEHRGLLKSALGILAGRLKEDQADLTLDQLSRHAFEYLQNFRSTVPSLNTALCLTQLLIVLSQYGGSNHRTYREQITSLTKHFLCQEWVTASGEKERGNKYNETLQTLLSIYLEHTDDVLKAVEEIAGEGVPELLNAAKDANSRSWPTLNRQTFLVYYKCMMSELEKAVRKIPPSKQMDNQEMQSEKLLTWNLAVRDFHILINLVKMFDSRPVLTVCLKYGRLFLESFLKLGMPLLDYSFKKHKEDVQGLLKTFQLSTRQLHHMCGHSKIRQDTGLTNHVPALKKSLEQFVYRVKAMLTLNHCQEAFWLGNLKNRDLKGEEILSQRSQAADEEEEESSQLQSEAEESDSDERNDGQEEVEESDESD
Protein: Small ArfGAP2 (X6RCC3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MWKPMEHSQRRRQDFEIYGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGL
Protein: Serine/threonine-protein kinase cot-1 (EC 2.7.11.1) (Colonial temperature-sensitive protein 1) (P38679)
Organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function: Protein kinase required for hyphal elongation.
Interaction partners:
- Cell wall biogenesis protein phosphatase Ssd1
- Cell morphogenesis protein
- protein-tyrosine-phosphatase
- Probable maintenance of ploidy protein mob1
- Protein kinase activator
- MOB-2A
- Conidiophore development protein hymA
- pH-response transcription factor pacC/RIM101
- Cell morphogenesis protein Sog2
Sequence:
MDNTNRPHLNLGTNDTRMAPNDRTYPTTPSTFPQPVFPGQQAGGSQQYNQAYAQSGNYYQQNHNDPNTGLAHQFAHQNIGSAGRASPYGSRGPSPAQRPRTSGNSGQQQTYGNYLSAPMPSNTQTEFAPAPERNPDKYGPNANNNQKKCSQLASDFFKDSVKRARERNQRQSEMEQKLGETNDARRRESIWSTAGRKEGQYLRFLRTKDKPENYQTIKIIGKGAFGEVKLVQKKADGKVYAMKSLIKTEMFKKDQLAHVRAERDILAESDSPWVVKLYTTFQDANFLYMLMEFLPGGDLMTMLIKYEIFSEDITRFYIAEIVLAIDAVHKLGFIHRDIKPDNILLDRGGHVKLTDFGLSTGFHKLHDNNYYTQLLQGKSNKPRDNRNSVAIDQINLTVSNRAQINDWRRSRRLMAYSTVGTPDYIAPEIFTGHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHSLYFPDDITLGVDAENLIRSLICNTENRLGRGGAHEIKSHAFFRGVEFDSLRRIRAPFEPRLTSAIDTTYFPTDEIDQTDNATLLKAQQAARGAAAPAQQEESPELSLPFIGYTFKRFDNNFR
Protein: COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) (P61201)
Organism: Homo sapiens (Human)
Function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9535219}. Nucleus {ECO:0000269|PubMed:10207062}.
Interaction partners:
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 8
- COP9 signalosome complex subunit 7b
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 7a
- COP9 signalosome complex subunit 3
- E3 ubiquitin-protein ligase RBX1
- Cullin-2
Sequence:
MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA
Protein: Golgi apparatus membrane protein TVP18 (TLG2 compartment vesicle protein of 18 kDa) (Q04767)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Golgi membrane protein involved in vesicular trafficking.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16107716, ECO:0000269|PubMed:17178117}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16107716, ECO:0000269|PubMed:17178117}.
Interaction partners:
- Golgi apparatus membrane protein TVP15
- Golgi apparatus membrane protein TVP23
- Nuclear transport factor 2
- Golgi apparatus membrane protein TVP38
- DNA repair protein RAD10
Sequence:
MALSLGQFINVGGMVKDLKSFNFSVYGRWFGYINIILCIALGIANLFHVSGVIAFGIISIIQGLVILFIEIPFLLKICPLSDNFIEFIKRFETNGWRCLFYLAMAIIQYISIAVMATSLIVVAVGLTISSISYAVAYTKHQEFQNTNIIKNPTDDDFPHEAVVREML
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (Complex I-B14.7) (NADH-ubiquinone oxidoreductase subunit B14.7) (K7EMT4)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004292}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004292}; Matrix side {ECO:0000256|ARBA:ARBA00004292}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 7
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- Acyl carrier protein, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial
- Partner and localizer of BRCA2
Sequence:
XPKVFRQYWDIPDGTDCHRKAYSTTSIASVAGLTAAAYRVTLNPPGTFLEGVAKVGQYTFTADTGSERPRGSCCARLEALALPVYPAAAVGAVFGLTTCISAHVREKPDDPLNYFLGGCAGGLTLGARTTLTHGSPGPSQATVAVAPLSGRAAVSAAGGCVFLLLPACV
Protein: SEC24 homolog B, COPII coat complex component (F6VJC5)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
Sequence:
PPPPPSQHQQQQQQQQQQQQQQQSHSGYSSLPWSGPALPPAQDSLIRNQMGSLATANSHPTNNENVQPPKSSSVVSTVLPGPSSTRMPPAPSHPVGPVPSAPPPPEQMQTKGVDSSSTTSSASPLPNSYDALEGGSYPDMHSSSASSPVPDHALEPSPTLAQALSAAPTPPAAQPAKVAKPFGYGYPALQPAYQNAAPPPMPAAHPSGPAYTGYPQHYPGVNQLSSGLGGLSLQSSPQPESLRPVNLTQEKNILPPTPIWAPVPNLSAELSKLNCSPDSFRCTLTSIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFLYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTVLCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPSMFINTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVHHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIFYYPSFHSTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTALVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAVCLLANMAVDRSVSSSLSDARDALVNA
Protein: GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (G5EER4)
Organism: Caenorhabditis elegans
Function: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Interaction partners:
- GDP-mannose 4,6 dehydratase 1
- GDP-mannose 4,6 dehydratase 2
- L-fucokinase domain-containing protein
- Ubiquitin-conjugating enzyme E2 ubc-18
- UDP-glucose 4-epimerase
- Ubiquitin-like domain-containing protein
- Alpha-
- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Alpha-
- Fatty acid synthase
Sequence:
MKTILVTGGTGLVGSAIKKVVETTEKRDDEKWVFIGSKDCDLENLEETRELFESVKPTHVIHLAAMVGGLFHNLAHNLQFFRKNMAINDNVLALCHEFDVIKCVSCLSTCIFPDKTSYPIDETMVHLGPPHDSNFGYSYAKRMIDVLNKGYAQEHGRKYTSVVPCNVFGPHDNYNLQSGHVLPALIHKAYVAQRDGTPLQVYGSGTPLRQFIYSIDLARLFIRVVREYEDVEPIILSVNESDEVSIRDAVSAVVKAIDFTGDVEYDTSKADGQFKKTASNEKLLKLFPDFQFTPFEQAIQESVQWFVDNYETARK
Protein: Aquaporin TIP4-2 (Tonoplast intrinsic protein 4-2) (ZmTIP4-2) (ZmTIP4;2) (Q9ATL5)
Organism: Zea mays (Maize)
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Tonoplast.
Interaction partners:
- Aquaporin SIP2-1
Sequence:
MAKLVNKLVDSFDHDEAPAPDVGCVRAVLAELVLTFLFVFTGVSASMAAGAGGKPGEAMPMATLAAVAIAHALAAGVLVTAGFHVSGGHLNPAVTVGILVRGHITKLRALLYVAAQLLASSLACILLRYLSGGMVTPVHALGAGIRPMQGLVMEVILTFSLLFVTYAMILDPRSQVRTIGPLLTGLIVGANSLAGGNFTGASMNPARSFGPAMATGVWTNHWVYWIGPLLGGSLAGFVYESLFMVNKTHEPLLNGDI
Protein: ATP-dependent Clp protease ATP-binding subunit ClpA (P0ABH9)
Organism: Escherichia coli (strain K12)
Function: ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins.
Interaction partners:
- ATP-dependent Clp protease proteolytic subunit
- ATP-dependent Clp protease adapter protein ClpS
- ATP-dependent Clp protease ATP-binding subunit ClpX
- ATP-dependent protease subunit HslV
- Stringent starvation protein B
- ATP-dependent protease ATPase subunit HslU
- Protein GrpE
- Chaperone protein DnaK
- ATP-dependent zinc metalloprotease FtsH
- Lon protease
Sequence:
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
Protein: Transient receptor potential cation channel subfamily V member 6 isoform X1 (Transient receptor potential cation channel, subfamily V, member 6) (F1QN56)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Sodium calcium exchanger 1n
- Cleavage and polyadenylation-specific factor 4.
- Transient receptor potential cation channel, subfamily M, member 4a.
- Calmodulin
- Solute carrier family 12 member 10, tandem duplicate 2
- Transient receptor potential cation channel, subfamily A, member 1a.
- Sodium/hydrogen exchanger
- Short transient receptor potential channel 6a isoform X1
- Short transient receptor potential channel 4b isoform X1
- Forkhead box I3a.
Sequence:
MPPAISGEINHWWRQMRFRLQHKKGWNEMLDETFLMQTKRVNDIPLFSATKENNAACIKKLLDCSSTDIFERGELGETALHVAVMNDNFEAAVALMNGAPELINEPMTSELYHGLTALHIAVINQNPNLIWEMIKRGADVTTPRVTGMYFRKRREGLFYYGEHILAFAACVGNKDIMSMLIKAGANIRAQDSRGNTILHLLVLQPNKTTACQIFDFLLAQDAEQDSALPLDMVPNYKGLTPFKLAARDGNVVVFQHLVNRRKVVQWSLGPVSSYLYDLTEIDSRVDEHSVLEIIATSHKKEARRILELTPVRQLITLKWNLYGKHYFRSLMVIYLVYISIFTVCCINRPLKGIPENYTKAGNDHTIKIKKTFKESYQSYTDQLRLIAEIISLIGAIIILLIEIPGILAVGVKRFFGQTALGGLFHVTLISYALLVLLLCGLRVTGIQGELIPMAFSLILGWFSLVYFARGFEMLGPYVIVIQKSIFGDITKFMWLSIIFLIGSSAALWIFYMTQEPLALPQYRSFPITLFSQFEVSVGQIDLPVDHTLFTHPVVYWTHVCFSLISNVLLFNLLVAMMSDTQWRVTQERDELWRTQVVATTLMLERKLPQCLWPRLGVCGLMFGLGERWYLRVEDRNDIMAQKLKRYVDAFSKDVEAPKEEKPSKSDGEQSIAESNKEKSKKSKQYWSLIRRSIECEKEECVDCPNFKFL
Protein: High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form] (O15431)
Organism: Homo sapiens (Human)
Function: High-affinity, saturable copper transporter involved in dietary copper uptake.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11734551, ECO:0000269|PubMed:12023893, ECO:0000269|PubMed:15326162, ECO:0000269|PubMed:17525160, ECO:0000269|PubMed:20451502, ECO:0000269|PubMed:26205368, ECO:0000269|PubMed:26945057, ECO:0000269|PubMed:35913762}; Multi-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000269|PubMed:26945057}; Multi-pass membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000269|PubMed:26945057}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:Q8K211}; Multi-pass membrane protein {ECO:0000255}. Late endosome membrane {ECO:0000250|UniProtKB:Q8K211}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8K211}; Multi-pass membrane protein {ECO:0000255}. Note=The localization is controlled by the intra and extra-cellular copper concentration (PubMed:15326162, PubMed:19740744, PubMed:23658018, PubMed:26205368, PubMed:26945057). Under conditions of elevated extracellular copper concentrations, it is rapidly internalized by endocytosis from the plasma membrane by a clathrin- and dynamin-mediated process and degradated in order to prevent intracellular copper accumulation and to reduce the transport of the copper across the membrane (PubMed:15326162, PubMed:19740744, PubMed:23658018, PubMed:26205368, PubMed:26945057). The internalized SLC31A1 is then localized in early endosomes, and, upon a low extracellular copper concentrations, it is transported back to the plasma membrane in a RAB11A-dependent recycling pathway (PubMed:26945057). Localizes to the apical membrane in intestinal epithelial cells (By similarity). Mainly localized on the basolateral side of renal tubular cells (By similarity). Localizes to the neuronal cell body plasma membranes (By similarity). {ECO:0000250|UniProtKB:Q8K211, ECO:0000250|UniProtKB:Q9JK41, ECO:0000269|PubMed:15326162, ECO:0000269|PubMed:19740744, ECO:0000269|PubMed:23658018, ECO:0000269|PubMed:26205368, ECO:0000269|PubMed:26945057}.
Interaction partners:
- Copper-transporting ATPase 2
- Copper-transporting ATPase 1
- Copper transport protein ATOX1
- Copper chaperone for superoxide dismutase
- Cytochrome c oxidase copper chaperone
- Solute carrier family 22 member 2
Sequence:
MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH
Protein: ADP-ribosylation factor-like 6 interacting protein (ADP-ribosylation factor-like 6-interacting protein 1) (ADP-ribosylation factor-like protein 6-interacting protein 1) (Arl6ip1 protein) (Q7ZWB4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- FAU ubiquitin-like and ribosomal protein S30 fusion b
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein uL15m
- 40S ribosomal protein S15
- Ribosomal protein S3
- Mitochondrial ribosomal protein S9.
- Large ribosomal subunit protein bL36m
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein uS10m
Sequence:
MAEGDNKSANLLAQETSQLEEQLQGWGEVILAGDQILRWEKPWFPGALVSVTTILFTLIYYLDPSVLTGLSCTVMILCLADYLVPTLAPRVFGSNKWTTEQQQRFHEICGNLVKTQRRVLGWWKRLFALKEEKPKMYFLSVISSLVAVAWIGQQVHNLFLTYLIVSFLLLLPGLNQHGIITKYAGMAKREINKLLKQKEKKNE
Protein: Uncharacterized protein Rv1342c (P9WM19)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative lipoprotein LprD
Sequence:
MTAPETPAAQHAEPAIAVERIRTALLGYRIMAWTTGLWLIALCYEIVVRYVVKVDNPPTWIGVVHGWVYFTYLLLTLNLAVKVRWPLGKTAGVLLAGTIPLLGIVVEHFQTKEIKARFGL
Protein: Cation channel sperm-associated auxiliary subunit delta (CatSper-delta) (CatSperdelta) (Transmembrane protein 146) (Q86XM0)
Organism: Homo sapiens (Human)
Function: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CATSPER1 stability before intraflagellar transport and/or incorporation of the CatSper complex channel into the flagellar membrane.
Subcellular location: Cell projection, cilium, flagellum membrane {ECO:0000250|UniProtKB:E9Q9F6}; Single-pass type I membrane protein {ECO:0000255}. Note=Specifically located in the principal piece of sperm tail. {ECO:0000250|UniProtKB:E9Q9F6}.
Interaction partners:
- Cation channel sperm-associated auxiliary subunit beta
- Cation channel sperm-associated protein 1
- Cation channel sperm-associated auxiliary subunit gamma
- Cation channel sperm-associated protein 2
- Cation channel sperm-associated protein 3
- Cation channel sperm-associated protein 4
- Cation channel sperm-associated auxiliary subunit epsilon
- Cation channel sperm-associated auxiliary subunit zeta
- EF-hand calcium-binding domain-containing protein 9
- Cation channel sperm-associated auxiliary subunit TMEM262
Sequence:
MLMLMLVAAVTMWLRPLVTAQLCRSRTVRTGKVFNLIQDVQGDRLYFHPTTTRLIKHPCEKNIALYLGKQVFFTMDNFETSLLPFTIPTSMQVGVPEVTSAHFAGSLLLLVVDQKVYIYDYENNSWSMSLGIKHPVTHVSGDNCCYTGSLFCVHVSNLVFAYFRGDQISQTYIYYSNTGGFSFWKYHYDRQAEIIGSLGGIFHFFSLSQVAMLVVNQGKGMFKYSDHPLNRSFGLSFDYNGTLDILIAPGQRGILLLWFENSLLFSHNAGQLVDTVRVKKGDQTLFSSIFEAKITIHNIAVTENELAVITREDNLYYGNLGIVPSSIIKFADQYIWSEDVALMFRSPGTLEILTPLRDTAFPAFDFQKCLVNIQALLMDPELHVGKCKIEFLTGEFIYRMYTIDMHSQLELTASLIPQPGTSLIPLVMVSNPHSLGFQATFYENGYTSDGNTKYKLDIFLKQQQHWGRTDSNFTSSLKKATMSTLTVDIANKEISCVDIKPLSTLISVGCDLDKKIVIQNKVSACSMGILDPLTLQDNYSFIIEKEFYDPGFQGQQSSEDLHVFYSYQQLGCPLLVYYDTLWKPVVELWRKDSFQEVIDAEYVLLEVNGQFSYSYSLTAQSAMCTSQPQNWTTMIKEFGGPFFWNRENYVSCHDPNNNAPLRWPDVQYQILGGRTANQIIFGHNGFYVFYISIVDPYYSYCQLETIFSIYVYGAFPVQLVSAGVVILLIISSILGSVWLAYKTPKLLRTARGRRIKKCATQLCRRCKTVCQFRASATARAGTEPPGRHRTPHGGRSDH
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (C9JRV0)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAG
Protein: Probably inactive leucine-rich repeat receptor-like protein kinase At3g28040 (Q9LRT1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- At5g19500
- Protein DAY-LENGTH-DEPENDENT DELAYED-GREENING 1, chloroplastic
- Small ribosomal subunit protein uS4m
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- F14J22.5 protein
- Rac-like GTP-binding protein ARAC2
- Membrane lipoprotein
- ADP,ATP carrier protein
Sequence:
MGKQRRTMISFTLFLTLTMMSSLINGDTDSIQLNDDVLGLIVFKSDLNDPFSHLESWTEDDNTPCSWSYVKCNPKTSRVIELSLDGLALTGKINRGIQKLQRLKVLSLSNNNFTGNINALSNNNHLQKLDLSHNNLSGQIPSSLGSITSLQHLDLTGNSFSGTLSDDLFNNCSSLRYLSLSHNHLEGQIPSTLFRCSVLNSLNLSRNRFSGNPSFVSGIWRLERLRALDLSSNSLSGSIPLGILSLHNLKELQLQRNQFSGALPSDIGLCPHLNRVDLSSNHFSGELPRTLQKLKSLNHFDVSNNLLSGDFPPWIGDMTGLVHLDFSSNELTGKLPSSISNLRSLKDLNLSENKLSGEVPESLESCKELMIVQLKGNDFSGNIPDGFFDLGLQEMDFSGNGLTGSIPRGSSRLFESLIRLDLSHNSLTGSIPGEVGLFIHMRYLNLSWNHFNTRVPPEIEFLQNLTVLDLRNSALIGSVPADICESQSLQILQLDGNSLTGSIPEGIGNCSSLKLLSLSHNNLTGPIPKSLSNLQELKILKLEANKLSGEIPKELGDLQNLLLVNVSFNRLIGRLPLGDVFQSLDQSAIQGNLGICSPLLRGPCTLNVPKPLVINPNSYGNGNNMPGNRASGGSGTFHRRMFLSVSVIVAISAAILIFSGVIIITLLNASVRRRLAFVDNALESIFSGSSKSGRSLMMGKLVLLNSRTSRSSSSSQEFERNPESLLNKASRIGEGVFGTVYKAPLGEQGRNLAVKKLVPSPILQNLEDFDREVRILAKAKHPNLVSIKGYFWTPDLHLLVSEYIPNGNLQSKLHEREPSTPPLSWDVRYKIILGTAKGLAYLHHTFRPTTIHFNLKPTNILLDEKNNPKISDFGLSRLLTTQDGNTMNNNRFQNALGYVAPELECQNLRVNEKCDVYGFGVLILELVTGRRPVEYGEDSFVILSDHVRVMLEQGNVLECIDPVMEEQYSEDEVLPVLKLALVCTSQIPSNRPTMAEIVQILQVINSPVPHRIMDSF
Protein: Lipid-anchored plasma membrane protein CPP1 (C-terminally palmitoylated protein CPP1) (Cysteine-rich protein CPP1) (P38216)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cell membrane {ECO:0000269|PubMed:38159851}; Lipid-anchor {ECO:0000269|PubMed:38159851}. Note=Predominantly localizes to the growing bud and this localization pattern is dependent on endocytosis and polarized secretion. {ECO:0000269|PubMed:38159851}.
Interaction partners:
- Uncharacterized protein YBL081W
- Lipid-anchored plasma membrane protein CPP2
Sequence:
MSANDYYGGTAGEKSQYSRPSNPPPSSAHQNKTQERGYPPQQQQQYYQQQQQHPGYYNQQGYNQQGYNQQGYNQQGYNQQGYNQQGYNQQGHQQPVYVQQQPPQRGNEGCLAACLAALCICCTMDMLF
Protein: Exotoxin A (ETA) (EC 2.4.2.36) (NAD(+)--diphthamide ADP-ribosyltransferase) (Pseudomonas exotoxin) (PE) (P11439)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38.
Interaction partners:
- Exotoxin A regulatory protein
- Lysyl endopeptidase
- Non-hemolytic phospholipase C
- Protease LasA
- Exoenzyme T
- Acyl-homoserine-lactone synthase
- Elastase
- Hemolytic phospholipase C
- Secreted exoenzyme S
- Transcriptional activator protein LasR
Sequence:
MHLTPHWIPLVASLGLLAGGSFASAAEEAFDLWNECAKACVLDLKDGVRSSRMSVDPAIADTNGQGVLHYSMVLEGGNDALKLAIDNALSITSDGLTIRLEGGVEPNKPVRYSYTRQARGSWSLNWLVPIGHEKPSNIKVFIHELNAGNQLSHMSPIYTIEMGDELLAKLARDATFFVRAHESNEMQPTLAISHAGVSVVMAQAQPRREKRWSEWASGKVLCLLDPLDGVYNYLAQQRCNLDDTWEGKIYRVLAGNPAKHDLDIKPTVISHRLHFPEGGSLAALTAHQACHLPLETFTRHRQPRGWEQLEQCGYPVQRLVALYLAARLSWNQVDQVIRNALASPGSGGDLGEAIREQPEQARLALTLAAAESERFVRQGTGNDEAGAASADVVSLTCPVAAGECAGPADSGDALLERNYPTGAEFLGDGGDISFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTGLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYASQPGKPPREDLK
Protein: Ferric uptake regulation protein (H7C6K3)
Organism: Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU364037}.
Interaction partners:
- DNA-directed RNA polymerase subunit alpha
- Bll7632 protein
Sequence:
MSENTAPHHDDDVHAAALLSGRQPALTGCPWHDVNEMLQSAGLRPTRQRMALGWLLFGKGARHLTAEMLYEEATLAKVPVSLATVYNTLNQLTDAGLLRQVSVDGTKTYFDTNVTTHHHYYLENSHELVDIEDPHLALSKMPEVPEGYEIARIDMVVRLRKKR