wanglab/gogpt-training-data huggingface dataset:
Protein: Gliding motility lipoprotein GldH (Q8KRP0)
Organism: Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / BCRC 14874 / CCUG 350202 / NBRC 14942 / NCIMB 11054 / UW101) (Cytophaga johnsonae)
Function: Required for gliding motility and chitin utilization.
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:14594839}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:14594839}.
Interaction partners:
- GldK
- GldJ
- GldN
- GldB
- PSP1 domain protein
- GldD
- Candidate bifunctional family GT51 beta-glycosyltransferase/PBP transpeptidase
- Peptidyl-prolyl cis-trans isomerase
- GldM
- GldL
Sequence:
MRIKNSGILLLAAILLFSCDKKRVFDEYKSVGSAWHKDSVVTFDLPVLDSTKKYNLFVNLRDNNNYPFNNLFLIVAIETPSGFTKVDTLEYQMANPDGTLMGNGFTDIKESKLYYKEDVKFKGKYKVHIKQAVRESGKIPGVEALEGITDVGFRIEQKD
Protein: FLICE-associated huge protein, isoform A (FLICE-associated huge protein, isoform B) (LD48056p) (Q7K0L8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- FI05704p
- Histone RNA hairpin-binding protein
Sequence:
METPAYATKSGGELVLPEALEDLMDLEDQDAGGMKSNVKDKSMDLDIYHDLYDIEPAGSKKPDQMDRSLELDIYDDLDDFQKAEDRNTKELQAWEAKYEKALAEIEALKVENKALGKKIKTMEVNLQNLLDTAKAEVKRKETLIAELRNEKDDVCFRRKRARAFDVPGAREPESKRPKEFQSTPIDVRKYPETNRNPFKTAAKDAAKDDARKMMTKKDDTTKVVSKDVERGVKSKEDNKMATNKDDDKKSSSKDDAWKSRTREDAKKSVQRSKSPRPEHSKTTDRKSTAQARRPDPHRSRSPKHNSRRDHHRNQESSSRHAKRRSQSASPSKIQLPREKANAIITLTDDETNDQRSKSPVPVTVKLVTESQPAEKVVSNRRDAALETNANSSKESKVETKDITQPTNGLIAEPCIPKHEIIPGLSLINPESADFSKNEIKLDPVILQDRTEDSGHQLLNKEPIPKVVVLEKCKNILAEDCPADEQPLDKFKDGKESEETQAKLDKKEPFAVETAVETPSKEESNDNIVLSKNTTSQADVCSQHDENDEAEIREPMDQVNSVVESDLGVRIIEDIRLPKMANIDHFAVKVDNHGEAPAAVTDSALNQENLATQDQKICAEMKDPTIFTTSDETPIKSATILYAKPDSTKLDHSDEHDEVILETAIDMLKKEQDAASTAESTYPKLRIAEDAIEMALEQLHQQSPDETVVTSTSNRAPQTPKSLITILTQTPKQADPLRSQTKSKTVSPMATPKKTATEKTPVKKRKVNMDSSPQVPAHDVTIDETLGACSLQDESSTVTKRCSLGHTDYQYEQIKDEVILRVKRRGRRRKPTPMEIPTTAADKPI
Protein: Small ribosomal subunit protein RACK1 (H0Y8R5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWTLFAGYTDNLVRVWQVTIGTR
Protein: Kinesin-like protein (F4IC87)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSTTSGTGGVSYRNGTQRSSLRTQSSASTSSGGQKASVKSKSVLRKSSPAALGGGSSKSGGGGDAGVPGRVRVAVRLRPRNGEELIADADFADCVELQPELKRLKLRKNNWDTDTFEFDEVLTEYASQKRVYEVVAKPVVEGVLDGYNGTIMAYGQTGTGKTYTLGQLGEEDVADRGIMVRAMEDILAEVSLETDSISVSYLQLYMETVQDLLDPSNDNIAIVEDPKNGDVSLPGATLVEIRDQQSFLELLQLGEAHRFAANTKLNTESSRSHAILMVNVRRSMKTRDGLSSESNGNSHMTKSLKPPVVRKGKLVVVDLAGSERINKSGSEGHTLEEAKSINLSLSALGKCINALAENSSHVPFRDSKLTRLLRDSFGGTARTSLVITIGPSPRHRGETTSTIMFGQRAMKVENMVKIKEEFDYKSLSRRLEVQLDNLIEENERQQKAFVDEIERITVEAHNQISEAEKRYANALEDEKLRYQNDYMESIKKLEENWSKNQKKLAAERLALGEKNGLDITSNGNRSIAPALEEVSELKKLLQKEAQSKMAAEEEVNRLKHQLNEFKKVEASGNSEIMRLHKMLENETQQKEKLEGEIATLHSQLLQLSLTADETRRNLEQHGSEKTSGARDSLMSQLRLPQIQDPGNAEKPPVARLFEQVGLQKILSLLEAEDADVRIHAVKVVANLAAEEANQQQIVEAGGLTSLLMLLKNTEDETIHRVAAGAIANLAMNETNQELIMDQGGIGLLSSTAANAEDPQTLRMVAGAIANLCGNDKLQTKLRSEGGIAALLGMVRCGHPDVLAQVARGIANFAKCESRASTQAGTKRGKSLLIEDGALSWIVQNAKTETAAIRRHIELALCHLAQHEGNAKEMVKEGAMWELVRISRDCSREDIRSLAHRTLTSSPTFLTELRRLRVDIR
Protein: Toll-like receptor 3 (F1LN63)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Protein unc-93 homolog B1
- TIR domain-containing adapter molecule 2
- TNF receptor-associated factor 6
- Myeloid differentiation primary response protein MyD88
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- Receptor-interacting serine/threonine-protein kinase 1
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
- Interferon beta
- Glycogen synthase kinase-3 beta
- Mitogen-activated protein kinase kinase kinase 7
Sequence:
MKGRSSYLIYSFGGLLSLWILVVSSTNQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRGLPPANFTRYSQLALLDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFAFCTNLTELHLMSNSIRKIKSNPFKNQKSLIKLDLSRNGLSSTKLGTGVQLENLQELLLAKNKIFALRSEELDFLGNSSLQKLDLSSNPLKEFSPGCFHAIGKLFVLLLNNAQLNLNLTEKLCWELSNTSIQNLSLANNQLLATSNSTFSGLKQTNLTSLDLSYNSLRYVGNDAFSWLPHLKYLSLEYNNIQSLTPHSFRGLSNLRYLSLKRAFTKQSVALASHPNIDDFSFQWLKCLEHLNMDDNTIPGIKSNTFTGLVSLKYLSLSKTFTGLQTLTNETFVSLTHSPLLTLNLTKNHISKIASGTFSWLGQLRILDLGLNEIEQELTGQEWRGLGNIFEIYLSYNKYLQLTSKSFTLVPSLQRLMLRRVALKSVDISPSPFRPLYNLTILDLSNNNIANLNEDLLEGLENLEILDFQHNNLARLWKHANPGGPVNFLKGLSHLHILNLESNGLDEIPVKVFKNLFELKSINLGLNNLNTLLPSIFDDQTSLRSLNLQKNLITSVEKSVFGPAFHNLNSLDMSFNPFDCTCESIAWFVTWLNQTHTNIPELSTHYLCNTPQRYHGLPVKLFDTSSCKDSAPFQLLFIINTSTLLTFILAVLLIHFEGWRISFYWNVSVHRILGFKEIDAQGEQFEYTAYIIHAQKDRDWVWEHFSPMEEQDQSLKFCLEERDFEAGVLGLEAIVNSIKRSRKIIFVITHHLLKDPLCRRFKVHHAVQQAIEQNLDSIILIFLQNIPDYKLNHALCLRRGMFKSHCILNWPIQKERINAFHHKLQVALGSRNSAH
Protein: Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) (F8VW21)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPREDRATWKSNYFLKIIQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEK
Protein: Holin (Protein P35) (Q3T4L9)
Organism: Enterobacteria phage PRD1 (Bacteriophage PRD1)
Function: Isoform Holin: Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space. Determines the precise timing of host cell lysis (By similarity). Participates with the endolysin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell (By similarity).
Subcellular location: Host cell inner membrane {ECO:0000250|UniProtKB:P03705}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P03705}. Note=Classified as a class I holin. {ECO:0000305}.
Interaction partners:
Sequence:
MMENDEWWKYLIFPLVATLGGIVNYSKRALAMKRFSKLEFAVEAVSAAFVGLMVTLGGAAMDLSPHWLGMAAGMSGWMGADFVKAVFSQFVQSKIAPINQPGPIDSDNDKPGRTFND
Protein: Secapin-2 (I1VC85)
Organism: Apis mellifera (Honeybee)
Function: Serine protease inhibitor which exhibits antifibrinolytic, antielastolytic and antimicrobial activities (By similarity). Displays antimicrobial activity against bacteria and fungi (By similarity). Likely functions in the innate immune response to microbial infection and possibly in the venom, as an antifibrinolytic agent (By similarity). Induces hyperalgesia and edema mediated by leukotrienes when injected into mice. Does not induce hemolytic activity, mast cell degranulation, or chemotactic activity for polymorphonucleated leukocytes (PMNL).
Subcellular location: Secreted {ECO:0000269|PubMed:25017240}.
Interaction partners:
Sequence:
MKNYSKNATYLITVLLFSFVTMLLIIPSKCEAVSNDMQPLEARTADLVQQPRYIIDVPPRCPPGSKFVHKRCRVIVP
Protein: Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Pineal night-specific ATPase) (Wilson disease-associated protein homolog) (Q64535)
Organism: Rattus norvegicus (Rat)
Function: Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:P35670}; Multi-pass membrane protein {ECO:0000255}. Late endosome {ECO:0000250|UniProtKB:P35670}. Note=Predominantly found in the trans-Golgi network (TGN). Not redistributed to the plasma membrane in response to elevated copper levels. {ECO:0000250|UniProtKB:P35670}.
Interaction partners:
- Copper transport protein ATOX1
- Copper chaperone for superoxide dismutase
- Ceruloplasmin
- Copper-transporting ATPase 1
- High affinity copper uptake protein 1
- COMM domain-containing protein 1
- Cytochrome c oxidase copper chaperone
- Metallothionein
- Metallothionein 2, pseudogene 1
- Natural resistance-associated macrophage protein 2
Sequence:
MPEQERKVTAKEASRKILSKLALPTRPWGQSMKQSFAFDNVGYEGGLDSTCFILQLTTGVVSILGMTCHSCVKSIEDRISSLKGIVSIKVSLEQGSATVKYVPSVLNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDINKLESTNLKRAAVPPIQNSNHLETPGHQQNHLATLPLRIDGMHCKSCVLNIEGNIGQLPGVQNIHVSLENKTAQVQYDSSCITPLFLQTAIEALPPGYFKVSLPDGLEKESGSSSVPSLGSSQRQQEPGPCRTAVLTITGIPRDSSVQPMEDMLSQMKGVQQIDISLAEGTGAVLYDPSVVSSDELRTAVEDMGFEVSVNPENITTNRVSSGNSVPQAVGDSPGSVQNMASDTRGLLTHQGPGYLSDSPPSPGGTASQKCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEVIQSPRIAQLIEDLGFEAAIMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIGFHASLAHRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLMIYMLIPSSKPHETMVLDHNIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAYKSLRHKSANMDVLIVLATTIAYAYSLVILVVAIAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLVDVATLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCKVSNVESILAHRGPTAHPIGVGNPPIGEGTGPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALASITLKSMGVDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADVGIAIGTGTDVAIDAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMGSAAASSVSVVLSSLQLKCYRKPDLERYEAQAHGRMKPLSASQVSVHVGMDDRRRDSPRATPWDQVSYVSQVSLSSLTSDRLSRHGGMAEDGGDKWSLLLSDRDEEQCI
Protein: Uncharacterized oxidoreductase YghA (EC 1.-.-.-) (P0AG84)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Catalase HPII
- Uncharacterized zinc-type alcohol dehydrogenase-like protein YbdR
- Protein/nucleic acid deglycase 2
- Methylglyoxal reductase DkgA
- Aldehyde reductase Ahr
- Aldehyde reductase YahK
- Uncharacterized protein YbhP
- NADH-quinone oxidoreductase subunit C/D
Sequence:
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
Protein: Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1) (Q9HCP0)
Organism: Homo sapiens (Human)
Function: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN.
Subcellular location: Cytoplasm.
Interaction partners:
- Casein kinase I isoform gamma-2
- Casein kinase I isoform gamma-3
Sequence:
MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK
Protein: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase) (Q9P8I0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Mitochondrion matrix.
Interaction partners:
- Proline dehydrogenase
- Proline dehydrogenase
- Glutamate 5-kinase
- Ornithine aminotransferase
- glutamate-5-semialdehyde dehydrogenase
- Aspartate aminotransferase
- NAD-specific glutamate dehydrogenase
- NADP-specific glutamate dehydrogenase
- aspartate transaminase
- Aspartate aminotransferase
Sequence:
MQSSMLLRVRALPKTASVLSRTKTATYATYKVPRIDNEPNKHYAAGSPDRKALQEALARTQRNAPLSVPLVIAGKEVKSSSSLTQSNPASHGPVATYSNATAKDVQAAIESALEARKSWASTPFADRASVFLKAADLISTKYRYDVMALTMHGQGKNAWQAEIDSAAELCDFFRFGVKYAEDLYAQQPVHHAPGVWNRVEYRPLEGFVYAISPFNFTAIGGNLAGAPALMGNVVVWKPSPSAIASNWLVHQILLEAGLPKNVIQFVPGEAEEVTKTVLDHPDFAALHFTGSTNVFRNLYGQISTRVAAGKYRSYPRIVGETGGKNFHLIHKSADIRNAAVQTVRGAFEYQGQKCSATSRVYVASSIADSFLEQVASEAKSLKVGPPSDFTNFCGPVIHEASFTKLAKVIDEAKNDPELELLAGGSYDSSKGWYIQPTVYRTTNPDHPLLTRELFGPILVVYAYPDATEADFARIAQKIDATGEYGLTGSVFAQDREALAVANDVLRNAAGNFYINCKSTGAVVGQQPFGGARASGTNDKAGSGNLLSRFVSLRSIKEEFVPTYKVAYPSNEA
Protein: S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (P40363)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Serine hydrolase involved in the detoxification of formaldehyde.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10427036}.
Interaction partners:
- S-
- Formate dehydrogenase 1
- Translation machinery-associated protein 17
- Dihydroxyacetone kinase 2
- Dihydroxyacetone kinase 1
- Seipin
- Glyoxalase I
- Putative uridine kinase DAS2
Sequence:
MKVVKEFSVCGGRLIKLSHNSNSTKTSMNVNIYLPKHYYAQDFPRNKRIPTVFYLSGLTCTPDNASEKAFWQFQADKYGFAIVFPDTSPRGDEVANDPEGSWDFGQGAGFYLNATQEPYAQHYQMYDYIHKELPQTLDSHFNKNGDVKLDFLDNVAITGHSMGGYGAICGYLKGYSGKRYKSCSAFAPIVNPSNVPWGQKAFKGYLGEEKAQWEAYDPCLLIKNIRHVGDDRILIHVGDSDPFLEEHLKPELLLEAVKATSWQDYVEIKKVHGFDHSYYFVSTFVPEHAEFHARNLGLI
Protein: SKI family transcriptional corepressor 1 (Functional Smad-suppressing element on chromosome 15) (Fussel-15) (LBX1 corepressor 1) (Ladybird homeobox corepressor 1) (P84550)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional corepressor of LBX1 (By similarity). Inhibits BMP signaling.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MALLCGLGQVTLRIWVSLPSQSENGIGFLAARAFLRSGGMEALTTQLGPGREGSSSPNSKQELQPYSGSSALKPNQVGETSLYGVPIVSLVIDGQERLCLAQISNTLLKNYSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGEHKPPKLPENFAFDVVHECAWGSRGSFIPARYNSSRAKCIKCGYCSMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLSDKSATDELSHAWEDVKAMFNGGTRKRTFSLQGGGGGGANGGSGGQGKGGAGGGGGGGPGCGAEMAPGPPPHKSLRCGEDEAAGPPGPPPPHPQRGLGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKLPPPLFPHPYGFPTAFGLCPKKDDPVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGGAMFWGHQPSGAAKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAGSGAPEPLDGAEPAKESGLGAEERCPSALSRGPLDEDGTDEALPPPLAPLPPPPPPPARKGSYVSAFRPVVKDTESIAKLYGSAREAYGAGPARGPGPGAGSGGYVSPDFLSEGSSSYNSASPDVDTADEPEVDVESNRFPDDEDAQEETEPSAPSAGGGPDGEQPTGPPSATSSGADGPANSPDGGSPRPRRRLGPPPAGRPAFGDLAAEDLVRRPERSPPSGGGGYELREPCGPLGGPAPAKVFAPERDEHVKSAAVALGPAASYVCTPEAHEPDKEDNHSPADDLETRKSYPDQRSISQPSPANTDRGEDGLTLDVTGTHLVEKDIENLAREELQKLLLEQMELRKKLEREFQSLKDNFQDQMKRELAYREEMVQQLQIVRDTLCNELDQERKARYAIQQKLKEAHDALHHFSCKMLTPRHCTGNCSFKPPLLP
Protein: Biorientation of chromosomes in cell division protein 1-like 2 (Biorientation of chromosomes in cell division protein 1 pseudogene) (Protein FAM44C) (Q8IYS8)
Organism: Homo sapiens (Human)
Function: May play a role in proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q96IK1}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:Q96IK1}.
Interaction partners:
- Biorientation of chromosomes in cell division protein 1
- Stanniocalcin-2
Sequence:
MADGGGGGSGGAGPASTRASGGGGPINPASLPPGDPQLIAIIVGQLKSRGLFDSFRRDCKADVDTKPAYQNLSQKADNFVSTHLDKQEWNPPANDNQLHDGLRQSVVQSGRSEAGVDRISSQVVDPKLNHIFRPQIEQIIHEFLVAQKEAAVPALPPEPEGQDPPAPSQDTS
Protein: RNA-binding motif protein, X-linked 2 (Q4QRG7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MNPLTKVKLINELNEREAQLGIKETVSWHSVYKNSAWVFIGGFPYELTEGDIICVFSQYGEIANINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVANYRPPKDTDDIDDITKQLREEGCAPKPVSSSEEESAEEYAVPVKKPKKDKKEKKKKKKEKKEKKKALKEEKREGRSESSASSPVRVKKEKEDVAYEKYSVKGPAANRRDRADEQEQLKEKEREREEGKKTDRRHAETQQRERDREGEREGDKERERDRGRQRDGERQRERDGGRQRDGEKDRERERDGGRQRDGERQRERDGGRQRDGERDRERERDGGRQRDGDRDREQERDGGRQRDVERDQERERDGGRQRDGERDRERERDGGRQRDGVRDRKRERDGGRQRDEERVRERERDRDRERDRGNGKHRDHSREREHRRN
Protein: Probable NOT transcription complex subunit VIP2 (Protein VIRE2 INTERACTING PROTEIN2) (NbVIP2) (Q52JK6)
Organism: Nicotiana benthamiana
Function: Transcriptional regulator required for Agrobacterium-mediated stable genetic transformation by T-DNA integration in host genome, but not for T-DNA transient expression.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MQGTLTSRNTAINNVPSSGVQQSGNNLSGGRFVPNNLPSALSQIPQGNSHGHSGMTSRGGTSVVGNPGYSSNTNGVGGSIPGILPTFAAIGNRSSVPGLGVSPILGNAGPRMTNSVGNIVGGGNIGRSISSGAGLSVPGLASRLNMNANSGSGNLNVQGPNRLMSGVLQQASPQVLSMLGNSYPAGGPLSQNHVQAIGNFNSMGLLNDVNSNDGSPFDINDFPQLSSRPSSAGGPQGQLGSLRKQGLSPIVQQNQEFSIQNEDFPALPGFKGGNADYAMDPHQKEQLHDNTLSMMQQQHFSMGRSAGFNLGGTYSSNRPQQQLQHAPSVSSGGVSFSNINNQDLLSLHGSDVFQSSHSSYQQQGGGPPGIGLRPLNSSGTVSGIGSYDQLIQQYQQHQGQSQFRLQQMSTLGQPFRDQSLKSMQSQVAPDPFGMLGLLSVIRMSDPDLTSLALGIDLTTLGLNLNSAENLYKTFGSPWSDEPAKGDPEFTVPQCYYAKQPPPLNQAYFSKFQLDTLFYIFYSMPKDEAQLYAANELYNRGWFYHREHRLWFMRVANMEPLVKTNAYERGSYICFDPNTWETIHKDNFVLHCEMLEKRPVLPQH
Protein: GTP-binding protein Rab40c (Rab40c, member RAS oncogene family) (Q6Y2E6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}.
Interaction partners:
Sequence:
MGTQGSPVKSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNGIDYKTTTILLDGRRVKLELWDTSGQGRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGSGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS
Protein: O-ureido-serine racemase (EC 5.1.1.19) (D2Z026)
Organism: Streptomyces lavendulae
Function: Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent. Catalyzes the stereoinversion of O-ureido-L-serine to O-ureido-D-serine.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MIRMRTPSTLPFTKMHGAGNDFVVLDLRDGPDPSPELCRALADRHKGVGCDLVLGIREPRSARAVAAFDIWTADGSRSAQCGNGARCVAAWAVRAGLARGPRFALDSPSGTHEVDVLDADTFRVALAVPRFAPESIPLFGHDGEQDLYEADLGDGTRVRFAAVSMGNPHAVIEVDDTATAPVARVGRAVQASGLFLPTVNVGFARVESRDRVHLRVHEYGAGETLACGSGACAAAAVLMRRGRVDRNVSVVLPGGELRISWPDDAADVLMTGPAAFVYEGTFLHASV
Protein: PH domain-containing protein (Q54CZ1)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Arrestin domain-containing protein F
- Ras-interacting protein RIP3
Sequence:
MDCVITSGWLQKWSSKVLSESERSILDRSCSGTYHSSMATHGEGSLKARWFILQNDFLNYYDRPPKKIQDYTCLKGQIYLRGCKLKHGGLITPIYQHWSIGVAPNTSGSNQVWKSIVDQHQVNGQMTISLVTPNGVEYSFTNMGGLTNEDTIKNLENWAYSISYAIFLSNKTKDEPMCGWLNKRGEKGHQFKNTKRRWCTLQGTKLRYFSSIPKHNKIGSLKGIIDLTHLSEIADKVLTEVRSKNGTLVSNGNQDWNAQKPLTNGIGSSGGGGGLDCFGNNNQSFSSSSSSPSSSSTTISSSPNNNSSSSSSIQEFDEVSTIVALSLTINNEKKYVLIFDNKEDRIKWVNAITAAVEKSYTSGNALAETVGGGDVFQSINNNNDKQVLVSGWMRKTKANKWWEKRFFQLTQNSLIYYKEDPPQKTLGSIFLLVSSCRIIKQKSLDSLDWCFSIADSRGVEYFFNTETSDQMERWIKAIKVARKKMLLSLLDQGGKLIIPITIGKDCGLITVQTKESIRVNSLSNKLAFEIPMPNVKSVSVSGDQKLDVSFLPLDGEVSEKKVEFITQNPHGVLQLFKDLFSSQENTIN
Protein: Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) (P58295)
Organism: Rattus norvegicus (Rat)
Function: Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25480793}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glycine receptor subunit alpha-1
- Glutamate decarboxylase 1
- Glycine--tRNA ligase
- Vesicular inhibitory amino acid transporter
- Glycine receptor subunit beta
- Gephyrin
Sequence:
MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC
Protein: Non-structural protein NS-S (P16494)
Organism: Bunyamwera virus (BUNV)
Function: Inhibits host transcriptional machinery, by producing modifications to the phosphorylation state of the C-terminal domain (CTD) of RNA polymerase II. Inhibits phosphorylation at serine 2 in the heptapeptide repeat (YSPTSPS) of the CTD of RNA polymerase II, suggesting that the elongation step of transcription and/or 3'-end processing is prevented. Inhibition of host transcription machinery leads to shut off of host cell protein synthesis and inhibition of the host innate immune response. NSs also seems to be involved in the nuclear relocalization of host PABP1.
Interaction partners:
Sequence:
MMSLLTPAVLLTQRSHTLTLSVSTPLGLVMTTYESSTLKDARLKLVSQKEVNGKLHLTLGAGRLLYIIRIFLATGTTQFLTMVLPSTASVDSLPGTYLRRC