wanglab/gogpt-training-data huggingface dataset:
Protein: Zygote arrest protein 1 (Q86SH2)
Organism: Homo sapiens (Human)
Function: mRNA-binding protein that mediates formation of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes. MARDO assembly around mitochondria is directed by an increase in mitochondrial membrane potential during oocyte growth. Promotes formation of MARDO phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs. Maternal mRNAs stored in the MARDO are translationally repressed. Essential for female fertility and oocyte-to-embryo transition by coordinating maternal mRNA storage, translation and degradation.
Subcellular location: Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000250|UniProtKB:Q80SU3}. Cytoplasm {ECO:0000250|UniProtKB:Q80SU3}. Note=Specifically localizes to MARDO (mitochondria-associated ribonucleoprotein domain), a mitochondria-associated membraneless compartment that stores mRNAs in oocytes. {ECO:0000250|UniProtKB:Q80SU3}.
Interaction partners:
- Growth/differentiation factor 9
- NACHT, LRR and PYD domains-containing protein 5
Sequence:
MAALGDEVLDGYVFPACPPCSYRYPYPAATKGKGAAGGSWQQRGRGCLPASSPCSAGAASLSFPGCGRLTAAEYFDSYQRERLMALLAQVGPGLGPRARRAGSCDVAVQVSPRIDAAVQCSLGRRTLQRRARDPESPAGPGAEGTTGGGSFSQQPSRRGLEQGSPQNGAPRPMRFPRTVAVYSPLALRRLTAFLEGPGPAAGEQRSGASDGERGPPPARLQGPEEGEVWTKKAPRRPQSDDDGEAQAAVRASWEQPADGPELPPREAQEGEAAPRSALRSPGQPPSAGRARDGGDGREAAVAGEGPSPRSPELGKERLRFQFLEQKYGYYHCKDCNIRWESAYVWCVQGTNKVYFKQFCRTCQKSYNPYRVEDITCQSCKQTRCSCPVKLRHVDPKRPHRQDLCGRCKGKRLSCDSTFSFKYII
Protein: Lipid-anchored plasma membrane protein uvi15 (UV-induced protein uvi15) (P40388)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the maintenance of viability of cells in stationary phase and in starvation conditions.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P38216}; Lipid-anchor {ECO:0000250|UniProtKB:P38216}. Cell tip {ECO:0000269|PubMed:16823372}. Note=Also localizes to the site of cell division. {ECO:0000269|PubMed:16823372}.
Interaction partners:
- UV-induced protein uvi31
- EKC/KEOPS complex subunit SPAC4H3.13
- Protein-lysine N-methyltransferase rrg1
- Vacuolar-sorting protein snf7
- rRNA 2'-O-methyltransferase fibrillarin
Sequence:
MSAQQFYGDKGYAPAPPQQAYGGPNYYPPQQNYPQQGYAPPQGYPQGGYPAQQPMYVQQPQASDPGGDLCCGLLTGLACCCCLDAMF
Protein: Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-52); Kisspeptin-10 (Metastin45-54)] (Q6Y4S4)
Organism: Mus musculus (Mouse)
Function: Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.
Subcellular location: Secreted.
Interaction partners:
- KiSS-1 receptor
- Progonadoliberin-1
- Tachykinin-3
- Neuromedin-K receptor
- Gonadotropin-releasing hormone receptor
- Pro-FMRFamide-related neuropeptide VF
- Pro-FMRFamide-related neuropeptide FF
- Uridine 5'-monophosphate synthase
- Leptin
- Appetite-regulating hormone
Sequence:
MISMASWQLLLLLCVATYGEPLAKVAPLVKPGSTGQQSGPQELVNAWEKESRYAESKPGSAGLRARRSSPCPPVEGPAGRQRPLCASRSRLIPAPRGAVLVQREKDLSTYNWNSFGLRYGRRQAARAARG
Protein: EVE domain-containing protein (Q38AF0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNRKRPRSPAGVQYWLMKSEPNKFSIDDLKKCTRSPWDGVRNYAARNNMKLMKVGDCVLFYHSNAKPSGVVGLASVVKTAYPDHTALDPKSEYYDARASKKNPWEMVDVQFEEKFASIVSLEELKKEKKLQAMQLFSQSRLSVQPVEKSEYDHVVSLGRKK
Protein: Uncharacterized protein (Q38ED2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGAGASSDNAAISALAKSNTRAKLLVNGHTREVSSRSSIISRNTAVKKPNKTHKEEVARGDEEFHVVDEADEATLQVLNAVKEAERLVDVRGTVKLQLLHSCYPLLEQVPAHRFDHLAVLVYQKEGDVFASLGDVESAKTVYARAIQIAETRVARGEKEMYMVLKRYVLAMVGMARIWYEQERNTIGFTFANNQAQPPTSSNSSVCSDTSFTSSVLSDSSIFSLNQEVLKSIVPKQPRRRVGPTVSVVKIPRPKVTKPNYTTEDDFVLRSQMTRELKASPCELLLLRCIEVVEIGHRRQSELLIPALVELAQIYEDLHLYNRALLLVRRCLGILCVVYDYDHPWIIQLRRRSDYLVKCMEHWSKGKCATKIQATWKMYRAMCLLESVLGRTVTRHVWMPRPKVATNEDMAFLNDFVNDLPDGAVLAGGDGSTGETTPDRGPSIPVSRSSPNADASPEVLRRRFSHTSVPSTVVIHDSRVVGNSRNTHTDTTMQKTDQGDVVTVRTVTTHRVVTEQVVDSDKDSNGEECLEESYEDGSAAQRQSSGDTAKQVGRGNAMQITTVGGRGGGEEVVGAESLVQSISSYLSSPGDSKRRLRAWKAGKPE
Protein: Transcription factor bHLH155 (BHLH transcription factor gamma) (bHLH gamma) (Basic helix-loop-helix protein 155) (AtbHLH155) (bHLH 155) (LONESOME HIGHWAY-like protein 3) (bHLH transcription factor bHLH155) (Q58G01)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that may regulate root development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor bHLH168
- AT-rich interactive domain-containing protein 2
- Transcription factor bHLH153
- TRF-like 10
- Probable pectinesterase 8
Sequence:
MGSTSQEILKSFCFNTDWDYAVFWQLNHRGSRMVLTLEDAYYDHHGTNMHGAHDPLGLAVAKMSYHVYSLGEGIVGQVAVSGEHQWVFPENYNNCNSAFEFHNVWESQISAGIKTILVVAVGPCGVVQLGSLCKVNEDVNFVNHIRHLFLALRDPLADHAANLRQCNMNNSLCLPKMPSEGLHAEAFPDCSGEVDKAMDVEESNILTQYKTRRSDSMPYNTPSSCLVMEKAAQVVGGREVVQGSTCGSYSGVTFGFPVDLVGAKHENQVGTNIIRDAPHVGMTSGCKDSRDLDPNLHLYMKNHVLNDTSTSALAIEAERLITSQSYPRLDSTFQATSRTDKESSYHNEVFQLSENQGNKYIKETERMLGRNCESSQFDALISSGYTFAGSELLEALGSAFKQTNTGQEELLKSEHGSTMRPTDDMSHSQLTFDPGPENLLDAVVANVCQRDGNARDDMMSSRSVQSLLTNMELAEPSGQKKHNIVNPINSAMNQPPMAEVDTQQNSSDICGAFSSIGFSSTYPSSSSDQFQTSLDIPKKNKKRAKPGESSRPRPRDRQLIQDRIKELRELVPNGSKCSIDSLLERTIKHMLFLQNVTKHAEKLSKSANEKMQQKETGMQGSSCAVEVGGHLQVSSIIVENLNKQGMVLIEMLCEECGHFLEIANVIRSLDLVILRGFTETQGEKTWICFVTESQNSKVMQRMDILWSLVQIFQPKANEKG
Protein: Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2) (Q7TSU7)
Organism: Mus musculus (Mouse)
Function: May regulate basal insulin secretion.
Subcellular location: Cell membrane {ECO:0000269|PubMed:26324709}; Single-pass type I membrane protein {ECO:0000305}. Note=Localized along the sites of the cell contacts (PubMed:26324709). Colocalizes with E-Cadherin and beta-catenin (PubMed:26324709). {ECO:0000269|PubMed:26324709}.
Interaction partners:
- Nephrin
- Podocin
Sequence:
MLASALLVFLCCFKGHAGSSPHFLQQPEDMVVLLGEEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDSRPAPELLWFRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTVNAPPVVTALQPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRIVAGAASAATSLLMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSSRGPEEETGSSEDRGPIVHTDHSDLVLEEKEALETKDPTNGYYRVRGVSVSLSLGEAPGGGLFLPPPSPIGLPGTPTYYDFKPHLDLVPPCRLYRARAGYLTTPHPRAFTSYMKPTSFGPPELSSGTPPFPYATLSPPSHQRLQTHV
Protein: Prostaglandin E2 receptor EP4 subtype (Prostanoid EP4 receptor) (A3QK20)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Prostaglandin E synthase 3b
Sequence:
MKRTCGKYDRQVDWGSEYITSMNFHDMDLQLNATNNSVVKMSKTTLNGYPIPVIMFIVGVVGNVIAIVVLRKSRKEQKETTFYTLVCGLAVTDLLGTLLASPVTIATYVKGEWPGGMPLCQYSGFILLFFSLAGLSIICAMSVERYLAINHAYFYNHYVDQRVAGLTLGGIYVSNALFCALPSMGLGSVVIQHPGTWCFIDWHNKTDTTTATFSYMYASFSSVLILATVVCNVLVCAALIMMHKRFVRRTSLGTDQGRVAEIRRRRSFARLAAAEIQMVIVLIATSTVVLICSTPLVVQVFVNQLFNSAADSSARPNPDPDLKAIRIASVNPILDPWIYILLRKTVVQKILEKIKCLFCRIGGRSHRRNTSDFHCDNDLRTSSVVSRDLPSMGLPELPEVISTSQTYLYPLEAGQGMGCCGDSVPSRTCSTSTEQTLLQDSQVADFSSGENRTEKSTDFEESSLCEHSNTNEEQCSKHQPLQVTFTDETLSFQERTI
Protein: Uncharacterized transcriptional regulatory protein YLL054C (Q12244)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for growth on non-fermentable carbon sources.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- High affinity cysteine transporter
- Uncharacterized transcriptional regulatory protein YLR278C
Sequence:
MSIASQKKVKPSFVCLRCKQRKIKCDKLWPTCSKCKASSSICSYEVEPGRINKSPTIENAPHRDIRNITPASMSASGSFTSILNPSTKDWEMKNFAMNLSNAHDKLVVMNNTTIVDSPFAFHSILQHDLYAKALTTCIHERILIDVERHRENVSANNKKRELNLTIGDIGPLFFIDKAALKFIENTSKTSKLYPPIDFLYNTYDYEQAHPEENNDKISINILLEELSKYFLNKNEVDGLIVDFYKTIYPVYPLLEISLFEDNIRELLQLNEFNGYNIVFAGKDSRRKLETITLLTIILAFSYRRLSLSTSHSFKESFGVKSNNLTLLAHKLLALMNVFQYVNEHTLCCLLYFFILRYLNPDQADMYPTHSDILNLKFLENVAIKLGLNEEPFQYTRYVSESDDYPRLFNLRRKLWLGVQFLKFGILIPEGDSDILSLEYLRSFMKTDESLPELFERNYASTNNLDLSLMATAENIYHLHLSLQVLLTSCFPINGPSYLKEVLDNIDKTKDFLNQKFPLILSSLGEPRMKSLHINVPSSLANEESFDFSTFEENETFIANVISYTCTMNIYDSLSLHFENQCFKNALEYKTYYHRFTFTAIQDYLTLLKLISEYFNGSLLHLREPFGFATQKVVRFSIHRLLIFQATLLVRLFYKKDTCDRSSAAMGMLNDRNGRLSRVIEKMIKLMSYHMKLLVEIVISKLEKSYLGSFISVSIFRYIIYLVDTDALSAFISDYWKSDAVMDERYSRIHRIVGLKWGMGRDKSFSFTSKLNNPQFLGSLDLEILEELEKLISAQEFSRNFTEDVDESLQSEIDLMNYDNEALNQLMAIDLDKLLGIFPNLSNF
Protein: Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11) (Q8K2V6)
Organism: Mus musculus (Mouse)
Function: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPL12, and of UBE2E3 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 E3
- Importin-4
- Importin-13
- Importin-5
- Importin subunit beta-1
- Transportin-3
- Transportin-1
- Transportin-2
- Ubiquitin-conjugating enzyme E2 E2
Sequence:
MDLNSASSVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLVESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQHVSSGNEAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLEGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKTQLLPELQVSHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSCVIERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCVTPELLRIFQNMSPLLELSSENLRTCFKIINGYIFLSSTEFLQTYAAGLCQSFYELLPEITTEGQVQVLKVVENALKVNPVLGPQMFQRILPCVFRGVIEGERYPVVMSIYLAVMGRVLLQNTSFFSSLLNEMGHEFNQEMDQLLGNVIEMWVDRMDNITQPERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSQHEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQEFLQGF
Protein: Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (h-CPEB) (hCPEB-1) (Q9BZB8)
Organism: Homo sapiens (Human)
Function: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress. Required for cell cycle progression, specifically for prophase entry.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18923137, ECO:0000269|PubMed:28383716}. Nucleus {ECO:0000269|PubMed:18923137}. Cytoplasm, P-body. Cytoplasmic granule. Synapse. Membrane. Postsynaptic density {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Continuously shuttling between nucleus and cytoplasm (PubMed:18923137). Also found in stress granules. Recruited to stress granules (SGs) upon arsenite treatment. In dendrites (By similarity). Localizes in synaptosomes at dendritic synapses of neurons (By similarity). Strongly enriched in postsynaptic density (PSD) fractions (By similarity). Transported into dendrites in a microtubule-dependent fashion and colocalizes in mRNA-containing particles with TACC3, dynein and kinesin (By similarity). Membrane-associated (By similarity). Colocalizes at excitatory synapses with members of the polyadenylation and translation complex factors (CPSF, APLP1, TACC3, AURKA, SYP, etc.) including CPE-containing RNAs (By similarity). {ECO:0000250, ECO:0000269|PubMed:18923137}.
Interaction partners:
- Poly
- Symplekin
- Neuroguidin
- Fragile X messenger ribonucleoprotein 1
- Aurora kinase A
- Eukaryotic translation initiation factor 4E
- Probable ATP-dependent RNA helicase DDX6
- Cyclin-dependent kinase 1
- Poly
- Serine/threonine-protein kinase PLK1
Sequence:
MALSLEEEAGRIKDCWDNQEAPALSTCSNANIFRRINAILDNSLDFSRVCTTPINRGIHDHLPDFQDSEETVTSRMLFPTSAQESSRGLPDANDLCLGLQSLSLTGWDRPWSTQDSDSSAQSSTHSVLSMLHNPLGNVLGKPPLSFLPLDPLGSDLVDKFPAPSVRGSRLDTRPILDSRSSSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSLSGGGPRDPLKMGVGSRMDQEQAALAAVTPSPTSASKRWPGASVWPSWDLLEAPKDPFSIEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSAAFVEIKTTKFTKKVQIDPYLEDSLCHICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKNRDSS
Protein: Large ribosomal subunit protein uL16 (60S ribosomal protein L10) (Protein QM) (Ribosomal protein L10) (Q7ZV96)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the large ribosomal subunit (Probable). Plays a role in the formation of actively translating ribosomes. Plays a role in the embryonic brain development.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q6ZWV3}.
Interaction partners:
- Large ribosomal subunit protein eL20
- Ribosomal protein L15
- Small ribosomal subunit protein uS9
- Ubiquitin-ribosomal protein eL40 fusion protein
- 40S ribosomal protein S12
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS2
Sequence:
MGRRPARCYRYCKNKPYPKSRFCRGVPDPKIRIFDLGRKKAKVDEFPLCAHMVSDEYEQLSSEALEAARICANKYMVKTCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSVRTKAQNKEHVIEALRRAKFKFPGRQKIHVSKKYGFTKFNTCDFDNMLAEKRLIPDGCGVKYIPSRGPLSRWKALHAN
Protein: Probable deoxyhypusine synthase (DHS) (EC 2.5.1.46) (Q9VSF4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Interaction partners:
- Eukaryotic translation initiation factor 5A
- Deoxyhypusine hydroxylase
- Spermidine synthase, isoform A
- Arginase
- S-adenosylmethionine decarboxylase proenzyme
- Ornithine decarboxylase 1
- Trafficking protein particle complex subunit 2-like protein
- Ornithine decarboxylase 2
- Meiotic recombination protein W68
- Delta-1-pyrroline-5-carboxylate synthase
Sequence:
MSTEPSVAKDAVLKRSEALAENTPQVSGYDFNEGLDYSKLFESYVNTGFQATNLGLAIREINRMLDCRDQPLEADQIDSHETDDFIRRRSKCTVFLGYTSNLVSSGLRETIRFLAEHRMIDCIVTTAGGVEEDFIKCLAPTFMGSFELSGRDLRERGINRIGNLLVPNDNYCKFEDWVMPLLDEMLEEQKSQGTIWSPSKIIHRLGERIGDPSSIYYWAAKNQIPVFCPALTDGSLGDMMYFHSFRQPGLVVDILSDLRRLNTMAVKAVNSGMIIVGGGVIKHHICNANLMRNGADYSVFINTASEFDGSDSGARPDEAISWGKIRKDATPVKVYAEASLVFPLIVGETFAKRHHCAGKELPRETNQV
Protein: CRISPR-associated endonuclease Cas1 (EC 3.1.-.-) (P9WPJ5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRNA is required for all activities (Probable). This CRISPR-Cas system protects bacteria against transformation with plasmids containing DNA homologous to its spacer regions.
Interaction partners:
- CRISPR-associated endoribonuclease Cas2
- CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1
- CRISPR system Cms endoribonuclease Csm3
- CRISPR-associated endoribonuclease Cas6
- CRISPR system endoribonuclease Csm6
- CRISPR system Cms protein Csm4
- CRISPR system Cms protein Csm5
- CRISPR system Cms protein Csm2
Sequence:
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
Protein: 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (EC 1.1.1.141) (EC 1.1.1.232) (Eicosanoid/docosanoid dehydrogenase [NAD(+)]) (Prostaglandin dehydrogenase 1) (F6Q486)
Organism: Equus caballus (Horse)
Interaction partners:
Sequence:
MHVNGKVALVTGAAQGIGRAFAEELLHKGAKVALVDCNLEAGVKCKAALDEQFEPQKTLFIQCDVANQEQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLIPVAQQPVYCASKHGIIGFTRSAAMAANLMNSGVRLNAICPGFVNTPILESIEKEENMGQYIEYKDHIKDMMKFYGILDPSMIANGLITLIEDDALNGAIMKITTSKGIHFQNYDTIPFHTKTQ
Protein: Nuclear transcription factor Y subunit B-2 (AtNF-YB-2) (AtNF-YB2) (Transcriptional activator HAP3B) (Q9FGJ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the NF-Y/HAP transcription factor complex (By similarity). The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Nuclear transcription factor Y subunit C-3
- Nuclear transcription factor Y subunit C-9
- Nuclear transcription factor Y subunit C-4
- Nuclear transcription factor Y subunit C-2
- Nuclear transcription factor Y subunit C-1
- Nuclear transcription factor Y subunit A-2
- Nuclear transcription factor Y subunit A-4
- Nuclear transcription factor Y subunit A-5
- Nuclear transcription factor Y subunit A-1
- Nuclear transcription factor Y subunit C-7
Sequence:
MGDSDRDSGGGQNGNNQNGQSSLSPREQDRFLPIANVSRIMKKALPANAKISKDAKETMQECVSEFISFVTGEASDKCQKEKRKTINGDDLLWAMTTLGFEDYVEPLKVYLQRFREIEGERTGLGRPQTGGEVGEHQRDAVGDGGGFYGGGGGMQYHQHHQFLHQQNHMYGATGGGSDSGGGAASGRTRT
Protein: Hedycaryol synthase (EC 4.2.3.174) ((2E,6E)-hedycaryol synthase) (Terpene synthase 1) (CbTps1) (A0A140KFG9)
Organism: Camellia brevistyla
Function: Sesquiterpene synthase that catalyzes the formation of sesquiterpenes and sesquiterpenoid alcohols. Converts farnesyl diphosphate (FPP) to hedycaryol. Hedycaryol is likely to be one of the terpenes that attract insects for pollination of Camellia brevistyla (Probable).
Interaction partners:
Sequence:
MASSQVGDMVNGNAEPTRHLAKFPPSLWGDRFTSFTLDKQLWDKYGNEIEVLKEQVRSMVVAGGRKAAEQINLINVLERLGVSYHFEKEIEEQLEQLFAKFEDNEDYDLFTIALHFRIFRQHGYKMSCDVFNKFRDSNGEFKETVSNDVRGMLSLYEATYLKIRGEGFLDEAHAFTIAQLESLVGGPHLSSDLSEQVMHALKQSIHRGFPRLEAKHFISFYEKDAARNETLLRLAKLDFNQLQLSHREELCHIFRWWKELDLISKVPYARDRAVECFFWSTCAYYEPQHSVGRAVLTKIVLLLSVTDDTYDAYGTYDELKLYTNAVQRWDASAMDELPDYMKTLYRALLNVYDEVERDLAKQGRAYGVHHSKEAFKEIVRSYEIEAEWFKEGYVASFEEYMKNALVTSTGRLHTTSCFMGLEADVATTEAFEWILTKPKMVAASGAIGRLVDDVMSNDEEQERGHVATGLDCYMKQHGVSKQEAIVELYKMIENAWRDINEEMLKPTAISMKLLIHVLNLSRISDVVYKYVDGYTHPEIIKDHVISLFEDPIPM
Protein: Uncharacterized protein (Q387L0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Small ribosomal subunit protein mS29
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- DUF4460 domain-containing protein
- Ubiquitin-like domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Potassium voltage-gated channel, putative
Sequence:
MSRSTVFGPGSLYSFTKFGSFNRSPTNCTLNKRMKDIFRLENQKHIRNDFDRERRYRMCTKCGITTVTINFNNVPSARVGLWGRCADDKDYTHHRMVDITQREYEVLRESPVEKRLNWWRYER
Protein: Ribosomal protein S14 (Q6PBW3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Ribosomal protein S3
- Large ribosomal subunit protein eL21
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein eL34
- Ribosomal protein L37
- Large ribosomal subunit protein uL22
- 60S ribosomal protein L32
- Large ribosomal subunit protein eL36
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
Sequence:
MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQKCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL
Protein: Mitochondrial pyrimidine nucleotide transporter RIM2 (Replication in mitochondria protein 2) (P38127)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:7891656}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Mitochondrial RNA-splicing protein MRS3
- Mitochondrial RNA-splicing protein MRS4
- Protein CCC1
- Mitochondrial GTP/GDP carrier protein 1
- mRNA-binding protein PUF3
Sequence:
MPKKSIEEWEEDAIESVPYLASDEKGSNYKEATQIPLNLKQSEIENHPTVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINYVIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYAKAFNNGQETPMIHLMAAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGLSASYLGSVEGILQWLLYEQMKRLIKERSIEKFGYQAEGTKSTSEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRLRQTPKENGKRKYTGLVQSFKVIIKEEGLFSMYSGLTPHLMRTVPNSIIMFGTWEIVIRLLS