wanglab/gogpt-training-data huggingface dataset:
Protein: Phosphate acetyltransferase (EC 2.3.1.8) (Phosphotransacetylase) (P71103)
Organism: Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Acetate kinase
- Pyruvate:ferredoxin oxidoreductase
- Pyruvate:ferredoxin oxidoreductase
- Acetyl-CoA acetyltransferase
- Acyl-CoA dehydrogenase, short-chain specific
- Formate acetyltransferase
- 2-oxoacid:ferredoxin oxidoreductase, alpha subunit
- Butyrate kinase 2
- Butyrate kinase 1
- 2-oxoacid ferredoxin oxidoreductase, beta subunit
Sequence:
MDLIESIWECAKQDKKRIILAEGEEKRNLIAADKIIKEGLAELVLVGDENKIKEKASELNLDISKAEIMDPETSLKTETYARDFYELRKHKGMTIEKSEKMVRDPLYFATMALKDGYVDGMVSGAVHTTGDLLRPGLQIIKTAPGVKIVSGFFVMIIPDCDYGEEGLLLFADCAVNPNPTSDELADIAITTAETARKLCNVEPKVAMLSFSTMGSAKGEMVDKVKNAVEITKKFRPDLAIDGELQLDAAIDSEVAALKAPSSNVAGNANVLVFPDLQTGNIGYKLVQRFAKAKAIGPICQGFAKPINDLSRGCSSEDIVNVVAITVVQAQRGI
Protein: Serine/threonine-protein kinase DBF20 (EC 2.7.11.1) (P32328)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Is probably a Ser/Thr-protein kinase that may function in initiation of DNA synthesis and also in late nuclear division.
Interaction partners:
- DBF2 kinase activator protein MOB1
- Tyrosine-protein phosphatase CDC14
- Protein TEM1
- Cell cycle protein kinase DBF2
- Cell division control protein 15
- Guanine nucleotide exchange factor LTE1
- Sporulation-specific protein 12
- Cytokinesis protein 2
- Ingression protein 1
- CBK1 kinase activator protein MOB2
Sequence:
MFSRSDREVDDLAGNMSHLGFYDLNIPKPTSPQAQYRPARKSENGRLTPGLPRSYKPCDSDDQDTFKNRISLNHSPKKLPKDFHERASQSKTQRVVNVCQLYFLDYYCDMFDYVISRRQRTKQVLRYLEQQRSVKNVSNKVLNEEWALYLQREHEVLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPINRVRSFEQVRKMSYFAEINFETLRTSSPPFIPQLDDETDAGYFDDFTNEEDMAKYADVFKRQNKLSAMVDDSAVDSKLVGFTFRHRDGKQGSSGILYNGSEHSDPFSTFY
Protein: Uncharacterized protein C1F7.10 (Q09921)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MIRILVINPNSTVQMTESVKSVLDDCTPPNVQLEYLTCPPEGPKAIECVSDGVRSAAVLMKYFEDHPPQVDAFLVSCYSDHPLVTTLRETYRKPCTGIMQASILTALSLGRKVSVVTTTKRYEPLLTDGIHAMGISDSVFAGIASTGLAPLELDSKPRAEVDALLARTALRAVNEMGADVICLGCAGMTHMAHVLEKAVGPNIPIIDGTKAGVELLASLVRMNLFTSKQGVYQAVGSD
Protein: Acyl-CoA--sterol O-acyltransferase 1 (EC 2.3.1.-) (Sterol O-acyltransferase 1) (Q9SV07)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the esterification of cycloartenol. Not implicated in the formation of sterol esters in flowers or during seed maturation. Has a substrate preference toward saturated fatty acyl donors (16:0 > 18:0 > 16:1 > 18:1). Does not require triacyglycerols (TAGs) as a fatty acyl donor, and is unable to acylate diacylglycerol to produce TAG.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Phospholipid--sterol O-acyltransferase
Sequence:
MASFIKAWGLVIISLCYTFFIAKLVPKGIKRLILFFPVFLIFFIVPFLIYSLHLLGITAFFIAWLANFKLLLFALGRGPLSSNHKPLSLPIFLAVSCLPIKIQLSPKPTKTHSHEGSTEGPLIYTIKAVFVVLIIKAYEYSTKLPEKVVLTLYAIHIYFALEIILAATAAAVRAMSDLELEPQFNKPYLATSLQDFWGRRWNLMVTGILRPTVYEPSLQLFSVLGPNYSQILAAFGTFVVSGIMHELIFFYMGRLRPDWKMMWFFLINGFCTTVEIAIKKTINGRWRFPKAISQVLTLTFVMVTALWLFLPEFNRCNIVEKALDEYAAIGAFAVEVRRKLTAYLF
Protein: Homeobox protein DBX1 (Developing brain homeobox protein 1) (A6NMT0)
Organism: Homo sapiens (Human)
Function: Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGKPSDFSDSEEEEEGEEQEEITVS
Protein: Uncoordinated 115b, isoform D (Q8INN7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MYILIYISIPKHPQTDKTRPIYPSTLGTELRTELGKQKIYCAKCTKKCSGEVLRVADNHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKCANCQQYVEGEVVSTMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAESPTRATAHQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRCKACQAVLNGEYMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYLQGSAIWHPRCGPGPSESGIILNGGGGTSSVVGGASNGNFTDTECDRMSSSALSEMHYRTVSPGLILREYGRPNAEDISRIYTYSYLTDAPHYLRKPIDPYDKTPLSPHFHRPSSYATTASNAGSVAGSRPPSRPHSRTRSAMKVLVDAIRSETPRPKSPGMNNEEPIELSHYPAAKKPPPGEQPKIERDDFPAPPYPYTDPERRRRYSDTYKGVPASDDEDENVENGKPNGKVKNGEEQQRLQREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNASRTPSASKEPLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSYRSPPKPGYGFKTTTLPYIRNGFSSDFSYGGLGDKTHSTDLSCGKSEASVDSITEGDRRALMGGDLPASSTYSGALSYHYPQAGLIRRSLPNMSHSIISCANAKL
Protein: Roundabout 1 (O44924)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MHPMHPENHAIARSTSTTNNPSRSRSSRMWLLPAWLLLVLVASNGLPAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGALFFYRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEGNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQYVAADGTLQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSVDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGETSWAATLTVEKPGSTSLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIGYTVEYFSPDLQTGWIVAAHRVGDTQVTISGLTPGTSYVFLVRAENTQGISVPSGLSNVIKTIEADFDAASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLHVSADEKYVEGLRIHYKDASVPSAQYHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPSNSKTALTYEDVPSAPPDNIQIGMYNQTAGWVRWTPPPSQHHNGNLYGYKIEVSAGNTMKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMDPTHHVHPPRAHPSGTHDGRHEGQDLTYHNNGNIPPGDINPTTHKKTTDYLSGPWLMVLVCIVLLVLVISAAISMVYFKRKHQMTKELGHLSVVSDNEITALNINSKESLWIDHHRGWRTADTDKDSGLSESKLLSHVNSSQSNYNNSDGGTDYAEVDTRNLTTFYNCRKSPDNPTPYATTMIIGTSSSETCTKTTSISADKDSGTHSPYSDAFAGQVPAVPVVKSNYLQYPVEPINWSEFLPPPPEHPPPSSTYGYAQGSPESSRKSSKSAGSGISTNQSILNASIHSSSSGGFSAWGVSPQYAVACPPENVYSNPLSAVAGGTQNRYQITPTNQHPPQLPAYFATTGPGGAVPPNHLPFATQRHAASEYQAGLNAARCAQSRACNSCDALATPSPMQPPPPVPVPEGWYQPVHPNSHPMHPTSSNHQIYQCSSECSDHSRSSQSHKRQLQLEEHGSSAKQRGGHHRRRAPVVQPCMESENENMLAEYEQRQYTSDCCNSSREGDTCSCSEGSCLYAEAGEPAPRQMTAKNT
Protein: Peptide ABC transporter, permease protein (O69633)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363032}.
Interaction partners:
Sequence:
MGWYVARRVAVMVPVFLGATLLIYGMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLGGILHGDLGRAYSGLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLRQGGIFDSAVLVTGLVIIAIPIFVLGFLAQFLFGVQLEIAPVTVGERASVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADYVRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFNIHGVGGVLYQAVTRQETPTVVSIVTVLVLIYLITNLLVDLLYAALDPRIRYG
Protein: Hemogen (R4GDZ7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MEDPLEKEIPPTEIKDSDEGGIRRRLRDRDLLKKRKAEAEEKATNQAQSIKRVKKRTTTGTPGRKGRPRKEPIVIAEDLGLAQEVDPSPITIPVTEPELPTIAEIEPLQPVEPQQELVPEEAISEKPQEEFLIEDLGPDEEEDMPQKHLVIDTGDDEKPYNDVPEQSSIAIPMFAPAPDSSQPDNLSLTENLLF
Protein: Intraflagellar transport protein 122 homolog (Q38B65)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}.
Interaction partners:
- Uncharacterized protein
- WD repeat-containing protein 19
- Intraflagellar transport protein 140
- Uncharacterized protein
- IFT80/172/WDR35 TPR domain-containing protein
- Intraflagellar transport protein IFT88, putative
- Intraflagellar transport protein component, putative
- Intraflagellar transport protein 56 homolog
- Intraflagellar transport protein 57/55
- Intraflagellar transport protein A1
Sequence:
MLNTVKWAEHSGAEDEPNPPVYSLSYHPSGETIVAGCGVRVVVFDATTGAVRLSLKGHTDAVYTVTCFSDGKYFASGGADKTVILWTIDGEGVLKYQHRESVQALAHNPVTGGLVSVAGRDYGTWSAEQMKVGKSSLPAKGLCCAWSRNGQTLAIGLSDGSIIFVPSQGGEKVTVKRTAPVWAVVFSPISESGADVLVVGSCDRRLSFYTSDGKPASKEKEISCEPCSLSFYGGGKFLLVGGSNCEVSLFTKDGNLLVKVADADDCIWSVQASPKHQQLCCGTNSGVLKVVDINIPVVHSIFNDQFVFRDKMSDAVVHQLTLDKRLRIPCNGYIIKLAVYRDRVAVQLCDKFIVFELFYDDERKMKFQNVAIIRKRVSCDHLCVTFNGLVICCDRRLTMYDFQGNMRQEWTVESSVCCIKVIGGVEGRECLLLGLKNGLTLRMFVDNPFPTTLAKVNNSVKALDLSCDKTKLAVVDDNGLLQAFDLRNKNEVLFMANGVQAVAWNSEYDDMICYTTAVNTLNIKTGALPPHEQRLPGYVIGFKANRVFNVCGTIVDKIDVPHSQSLYRYIEKRDFESAHRIARLGVPDGDWKMLGMHAMMHLQLDVARKAFINIREVKLVELLNRLEMQQRLKGSKGEEDDGLLMGDIFAFQGKYQEASRHFLKAGHENKAIDMFCDLKMWTDAQRVCSNESHLKELIRQQARWAEDSENYIEAAALFQACGDKSRAIAMLCNAGDADKLMEMCRAMSKSEVALITECANYFKKQKLMQPAMYAYEKVGDYRSLICLHMEMKEWRKAFALLDLYPQYIREVYVPWANWLADNGNFTAALDAYRKAKWPREAVRMMESLAANSVICRRFQEAAFYFIHLAGEYGVLEDDQQLTEAEWAVRMKRSAECVRRAEIYYAYHFVYLHVTQPFTYDEVTLFNASRFVIAMTSNTTVPLNVGRGEVLYTLAHIASQLDMTRTARMAFERLHNVVLPTKVMEQIDVDSLVLRSKGFNDNEDLLDVCFRCKQIVQQFANAGDRCPTCAHPFVRSFVTFVNLPLVEFTLSNELSDTEAERIILTGAGRKNTENKTDGNNGEYNGWKADTGADVITFAEEEDNIDALMDHQLAALGRGGAMGTDPFSAQLKYILRPGRTNKGYQPFVVNADMLCRMRRDEVFIVKAGFGKLPVQNKYYRLVNRSVGIILCPGCQHFFKDDDYEYECMKGNGCPLCQYRMGKKPEKSMTKVLNDVLASMEKKKE
Protein: Putative lipoprotein LppJ (P9WK77)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Uncharacterized protein Rv2078
- Uncharacterized protein Rv2079
Sequence:
MPHSTADRRLRLTRQALLAAAVVPLLAGCALVMHKPHSAGSSNPWDDSAHPLTDDQAMAQVVEPAKQIVAAADLQAVRAGFSFTSCNDQGDPPYQGTVRMAFLLQGDHDAYFQHVRAAMLSHGWIDGPPPGQYFHGITLHKNGVTANMSLALDHSYGEMILDGECRNTTDHHHDDETTNITNQLVQP
Protein: RING finger protein PSH1 (POB3/SPT16 histone-associated protein 1) (Q12161)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Histone H3-like centromeric protein CSE4
- Polyubiquitin
- Histone H3
- FACT complex subunit SPT16
- Ubiquitin-ribosomal protein eS31 fusion protein
- Protein SCM3
- Histone H4
- FACT complex subunit POB3
- E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5
- Kinetochore-associated protein DSN1
Sequence:
MGDELHNRLLHQNDGTKDAILYKIIESLVCSICHDYMFVPMMTPCGHNYCYGCLNTWFASNTQKELACPQCRSDITTIPALNTTLQQYLSFILEKLRDQNDESFKKLLTTKTKEENDYKNDKEKDTLFDKVFKNSALAVADDSDDGITRCSNCHWELDPDEVEDGNVCPHCNARIRNYAGGRDEFDEEEYSEGELDEIRESMRRRRENRFASTNPFANRDDVSSEDDDSSEEEPMREHIPLGRWARSHNRSIAVDAVDDEDDEEEDEEEEEEMDSDLKDFIEDDEDDEDEDGSRRNLVLSALKNRHVIITDDEEEEQRRHATEEEDRDSDFYEHNDDGFVSGDSLDEDQKEVTRIQSSSDSEDRSLSYSGSSDVKDNNDDNTEELDDPQPKRQKRFRVVLGDSDDE
Protein: Non-classical export protein 1 (Q02820)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. May be part of the export machinery or may also be a substrate for non-classical export.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- mRNA-binding protein PUF3
- ATP synthase subunit J, mitochondrial
Sequence:
MVQYAPFLLGKFSDPLLAIMVGCLSYYVYERKMGRPQGHHLHELIKKRWDDRK
Protein: Immunoglobulin mu Fc receptor (IgM FcR) (Fas apoptotic inhibitory molecule 3) (FAIM3) (Regulator of Fas-induced apoptosis Toso) (O60667)
Organism: Homo sapiens (Human)
Function: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19858324, ECO:0000269|PubMed:21908424, ECO:0000269|PubMed:22675200, ECO:0000269|PubMed:30840890}; Single-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000269|PubMed:21908732}; Single-pass membrane protein {ECO:0000255}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:21908732}; Single-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:21908732}; Single-pass membrane protein {ECO:0000255}. Note=Continuously recycles between cytoplasmic pool and the plasma membrane to bind as much IgM as possible. {ECO:0000269|PubMed:30840890}.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted {ECO:0000269|PubMed:21908424}. Note=Detected in the serum. {ECO:0000269|PubMed:21908424}.
Interaction partners:
- B-lymphocyte antigen CD19
Sequence:
MDFWLWPLYFLPVSGALRILPEVKVEGELGGSVTIKCPLPEMHVRIYLCREMAGSGTCGTVVSTTNFIKAEYKGRVTLKQYPRKNLFLVEVTQLTESDSGVYACGAGMNTDRGKTQKVTLNVHSEYEPSWEEQPMPETPKWFHLPYLFQMPAYASSSKFVTRVTTPAQRGKVPPVHHSSPTTQITHRPRVSRASSVAGDKPRTFLPSTTASKISALEGLLKPQTPSYNHHTRLHRQRALDYGSQSGREGQGFHILIPTILGLFLLALLGLVVKRAVERRKALSRRARRLAVRMRALESSQRPRGSPRPRSQNNIYSACPRRARGADAAGTGEAPVPGPGAPLPPAPLQVSESPWLHAPSLKTSCEYVSLYHQPAAMMEDSDSDDYINVPA
Protein: GEO09167p1 (Nucleophosmin, isoform A) (Nucleophosmin, isoform B) (Q9VAC4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nucleoplasmin-like protein
- GH03795p
- Large ribosomal subunit protein uL18
- NHP2-like protein 1 homolog
- Single-stranded DNA-binding protein, mitochondrial
- Nucleolar protein 58
- Small ubiquitin-related modifier
- CG6459 protein
Sequence:
MESESFYGVTLSEKEAIAQFEVPDVPEEYIVHSHKLIIKQISLGPEAKTGEFNVVQAETNINDDGEKKTLKIPIAVLKVGETRSLRPNVEFPNGSVTFKLVQGSGPVHVCGKVEMNFGEFDDGQIYEEYSDEEEDSELEFDEEAAPQTNGKSNKKK
Protein: Uncharacterized protein C27B12.07 (O42997)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:16823372}; Single-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- mRNA export factor elf1
Sequence:
MFSLLRKAIDVNRSRITLHGIKVHSINTFRLIPYSLSLTKQIRFYASEGTDAGEMEKGLSVVNANHENRPFRDLEGYHFNTFTFLKTLMDKGYTEKEAEGLLEVTNMFVTDMLRHSHLNYLSEADFENCSYLFRTALSELRSEKINMRKDQISSLRSGLFSNQREVESLEQLVHEQLNKLNTESKMEFENRKNDTKNEVQQLSARIVELHNLLAVSLGKLRAENERQKWDQIRKAAGVVMAFTGFLVLVIPFGLGVRSRKKEKQDELDNLGSFNLDNKRDDYTDTNLSHM
Protein: (2R)-sulfolactate sulfo-lyase subunit alpha (EC 4.4.1.24) (Sulfolactate sulfo-lyase A) (Q58Y44)
Organism: Paracoccus pantotrophus (Thiosphaera pantotropha)
Function: Together with SuyB, desulfonates sulfolactate to pyruvate and sulfite.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:15758220}.
Interaction partners:
Sequence:
MLCVVTSDNSDFRLTAKADIPIGHKVALKALKAGDTVIKYHEDIGKMVGDAEVGGHVHTHNCKTKRW
Protein: ADP-ribosylation factor GTPase-activating protein effector protein 1 (ARF GAP effector protein 1) (Suppressor of ARF1 thermosensitive mutant protein 1) (Q04412)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: GTPase-activating protein (GAP) for the ADP ribosylation factors ARF1 and ARF2. May be involved in the endocytic pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Arf guanine nucleotide exchange factor SYT1
Sequence:
MDFYTTDINKNVVPLFSKGTVARTASKAQYPSWCNNALKLTNILLKSLRCKFQTNRCEDDRGFEVYCVILKSIALLMAAKESLILLQIPPSLPSGFPFRSPQLSFTYLSTRLSGSQHKSTHSHHINHQTHPIHSSSSNSNSNNRIPTKTDSSKQHTQHFSFANAGASNRDELLSIVRKIDKSNLKCCDCGSTATVEWVSINLLCILCIKCSGVHRSLGSHISKIRSLTLDNFTSLELMHLLQNNVSNSNVNAIYESNLRNFPVKKITANSDDSERSKFIIDKYQFKKFVIDSNQGREASLKSLIKAIHLDSVFMMQRAIAQSKYSLRELTASEKEQNDLNHSSIFQYSLKHYEIVDGTPIFFITEFLLCNGIHIDNLPKITTNWSPKVLEYWETKLEMYGTFQAVNTSRPRSGPHLNMHSNVDSASSYNKKHDLRVNIPERSASASKRWSLSSIPKSSQNLMSPTNLLTMHKSLKLAKKDKK
Protein: (2Z,6E)-hedycaryol synthase (HcS) (EC 4.2.3.187) (E4MYY0)
Organism: Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) (Streptomyces setae)
Function: Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (2Z,6E)-hedycaryol via a 1,11-cyclization.
Interaction partners:
- Uncharacterized protein
- Terpene synthase
- Putative nucleotide-binding protein
- Putative nucleotide-binding protein
- Putative nucleotide-binding protein
Sequence:
MAEFEIPDFYVPFPLECNPHLEEASRAMWEWIDANGLAPTERARDRMRRTGADLSGAYVWPRADLDTLTIGLKWIALTFRIDDQIDEDDTAERLPARMTAIDELRGTLHGLPVSGRSPTARALGALWQETALGRPATWCDAFIGHFEAFLQTYTTEAGLNAHGAGLRLDDYLDRRMYSVGMPWLWDLDELRLPIFLPGSVRTCGPMNKLRRAGALHIALVNDVFSVERETLVGYQHNAVTIIREAQGCSLQEAVDQVAVLVEAQLHTVLQARQELLEELDRQALPSRAREAAVDYAANVAANLSGQLVWHSSVERYAVDDLQSAADPRATPTTSSLGI
Protein: DSN1 component of MIS12 kinetochore complex (Q5JW54)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTSVTRSEIIDEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ
Protein: E3 ubiquitin-protein ligase ari-1.1 (EC 2.3.2.31) (O01965)
Organism: Caenorhabditis elegans
Function: E3 ubiquitin-protein transferase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 ubc-18 (By similarity). Acts with ubc-18 to regulate pharyngeal development.
Subcellular location: Nucleus {ECO:0000269|PubMed:16457801}. Cytoplasm {ECO:0000269|PubMed:16457801}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 ubc-18
- UBC core domain-containing protein
Sequence:
MSSDDEINMDDSDSSQGEIDDGCMSDDDGIVLESREQNSSDYKDNGEPDNEVLNHDSLEAEMKKTITDVQAVLQVKTGVCRILLHKYKWNKESLLERFYEHPDTTTFLIDAHVIPRRQERLPAGDAECDICCSLGELSGLSCNHRACTQCWKAYLTNKIANNAQSEIECMAPNCKLLIEDEKVMFYITDPTVIATYRKLIVASYVETNRLLKWCPGIDCGKAVRVSHWEPRLVVCSCGSRFCFSCGHDWHEPVNCRLLKLWLKKCNDDSETSNWINANTKECPKCMITIEKDGGCNHMTCKNTACRFEFCWMCLGPWEPHGSSWYSCNRFDDSAAKNARDAQEVSRANLQRYLFYYNRYMGHQQSLRLEGKLYATVKSKMEQMQTLSMSWIEVQFLRKAVDVLSECRRTLMFTYAFAFYLKRDNNAIIFESNQKDLEMETEQLSGFLERDLDNENLVTLKQKVQDKYRYVEHRRKVLLDHCSEGADQELWVFNE
Protein: Red-sensitive opsin-1 (Opsin-1, long-wave-sensitive 1) (Opsin LWS-1) (Red cone photoreceptor pigment 1) (Q9W6A7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Cone transducin alpha subunit, alpha transducing activity polypeptide 2) subunit alpha-2)
- Red-sensitive opsin-2
- Guanine nucleotide binding protein
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
- Gnb1l protein, beta polypeptide 1, like), beta polypeptide 1b isoform X1), beta polypeptide 1b)
Sequence:
MAEHWGDAIYAARRKGDETTREAMFTYTNSNNTKDPFEGPNYHIAPRWVYNVATVWMFFVVVASTFTNGLVLVATAKFKKLRHPLNWILVNLAIADLGETLFASTISVINQFFGYFILGHPMCIFEGYTVSVCGIAALWSLTVISWERWVVVCKPFGNVKFDAKWASAGIIFSWVWAAAWCAPPIFGWSRYWPHGLKTSCGPDVFSGSEDPGVQSYMVVLMITCCIIPLAIIILCYIAVYLAIHAVAQQQKDSESTQKAEKEVSRMVVVMIFAYCFCWGPYTFFACFAAANPGYAFHPLAAAMPAYFAKSATIYNPVIYVFMNRQFRVCIMQLFGKKVDDGSEVSTSKTEVSSVAPA
Protein: Cytoplasmic protein (J9W473)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Interaction partners:
Sequence:
MPPPPEVSPVTGNPVSPHYIHSSTLHFQDVNGRSLVLRGVNLSGSAKHPNNQPSHIREGFWETAEAGKGDFINKPLNLDDGSADLHLARLKAWGYNLLRYVFTWESLEHAGPKEYDYAYMDYIIAVLRKCKEWGFRVFMDPHQDVWSRFTGGSGAPLWTLYACGIDPYHLTATAAAYLHCEWPSAESPKPQDFPAMIWGTNYTHLANQTIWTFFFAGKTYAPKCIIDGKNIQDFLQDHFIDAVGELAKRIAEEAGDLLDECVIGWDSINEPGEGLIGCKDLAVIPAEQQLKKGPSPTPIEGMRLGMGEAQDVQAWNFGPMGPYRGSRQTIDPKGVKLWLSKEDDVKRGSGKWGWTRGKEWALGTCIWAHHGVWEIATSTLLRPDYFSTLPTNPGHQVDFVDDFWALHWLAYSSRIRLHHPESIHFIQAPVLRQPPKLPESFLKGRACSSPHFYDGLTLMTKHWNWFNADAIGVIRKKYWSIVQAVRIGEGPIRKMIQGELAVLKQDTIDILGNYPTLVGEIGIPYDMDDKKAYGYVDGGRGEGDYSSQQKAMDCSMNACDGPNCLNYAIWNYVPDNVHEWGDNWNGEDLSLWSVDDKEQESYHDSPRSDTPNFSTNSNSLTNSSATLTVPMSGASKLRPSPSVIDSGDFSPTLILDGSRAVAAFCRPYPVATVGIPERIDFDITSTKFKYAVRVRADDIANEQVYTEIYLPFVHYAASLNASRSAGHNPNLGQTTSTSADGDDSTVSSRQTSKVDLIEDERAIKSSDPSSVSIRSVPYSSFAQLSLDVTIVASHGRVEIQGQTLRWWYPVPGTGEEVYTIEVQRNGGALRRDLGYVQQGNFLDVCPECVIA
Protein: Copper-sensing transcriptional repressor RicR (Regulated in copper repressor) (O07434)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Under low copper conditions, represses the expression of lpqS, Rv2963, mymT, socA, socB, mmcO and its own expression. In the presence of copper, RicR dissociates from DNA, leading to the expression of the target genes. Members of the RicR regulon are important for copper resistance during infections and full virulence in a mouse model of infection.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Multicopper oxidase MmcO
- Putative permease Rv2963
- Lipoprotein LpqS
- Metallothionein
- Chloramphenicol efflux pump Rv0191
- Dihydroxy-acid dehydratase
Sequence:
MTAAHGYTQQKDNYAKRLRRVEGQVRGIARMIEEDKYCIDVLTQISAVTSALRSVALNLLDEHLSHCVTRAVAEGGPGADGKLAEASAAIARLVRS
Protein: Collagen alpha-4(IV) chain (Q9QZR9)
Organism: Mus musculus (Mouse)
Function: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000255|PROSITE-ProRule:PRU00736, ECO:0000269|PubMed:7962065}. Note=Colocalizes with COL4A3 and COL4A5 in GBM, tubular basement membrane (TBM) and synaptic basal lamina (BL). {ECO:0000250|UniProtKB:P53420, ECO:0000269|PubMed:7962065}.
Interaction partners:
- Collagen alpha-3
- Col4a5 protein
- Collagen, type IV, alpha 6
- Collagen alpha-1
- Collagen alpha-2
- CD44 antigen
- Platelet glycoprotein VI
- Integrin alpha-3
- Integrin alpha-1
- Integrin beta-6
Sequence:
MRCFFRWTKSFVTAPWSLIFILFTIQYEYGSGKKYGGPCGGRNCSVCQCFPEKGSRGHPGPLGPQGPIGPLGPLGPIGIPGEKGERGDSGSPGPPGEKGDKGPTGVPGFPGVDGVPGHPGPPGPRGKPGVDGYNGSRGDPGYPGERGAPGPGGPPGQPGENGEKGRSVYITGGVKGIQGDRGDPGPPGLPGSRGAQGSPGPMGHAGAPGLAGPIGHPGSPGLKGNPATGLKGQRGEPGEVGQRGPPGPTLLVQPPDLSIYKGEKGVKGMPGMIGPPGPPGRKGAPGVGIKGEKGIPGFPGPRGEPGSHGPPGFPGFKGIQGAAGEPGLFGFLGPKGDLGDRGYPGPPGILLTPAPPLKGVPGDPGPPGYYGEIGDVGLPGPPGPPGRPGETCPGMMGPPGPPGVPGPPGFPGEAGVPGRLDCAPGKPGKPGLPGLPGAPGPEGPPGSDVIYCRPGCPGPMGEKGKVGPPGRRGAKGAKGNKGLCTCPPGPMGPPGPPGPPGRQGSKGDLGLPGWHGEKGDPGQPGAEGPPGPPGRPGAMGPPGHKGEKGDMVISRVKGQKGERGLDGPPGFPGPHGQDGGDGRPGERGDPGPRGDHKDAAPGERGLPGLPGPPGRTGPEGPPGLGFPGPPGQRGLPGEPGRPGTRGFDGTKGQKGDSILCNVSYPGKPGLPGLDGPPGLKGFPGPPGAPGMRCPDGQKGQRGKPGMSGIPGPPGFRGDMGDPGIKGEKGTSPIGPPGPPGSPGKDGQKGIPGDPAFGDPGPPGERGLPGAPGMKGQKGHPGCPGAGGPPGIPGSPGLKGPKGREGSRGFPGIPGSPGHSCERGAPGIPGQPGLPGTPGDPGAPGWKGQPGDMGPSGPAGMKGLPGLPGLPGADGLRGPPGIPGPNGEDGLPGLPGLKGLPGLPGFPGFPGERGKPGPDGEPGRKGEVGEKGWPGLKGDLGERGAKGDRGLPGDAGEAVTSRKGEPGDAGPPGDGGFSGERGDKGSSGMRGGRGDPGRDGLPGLHRGQPGIDGPPGPPGPPGPPGSPGLRGVIGFPGFPGDQGDPGSPGPPGFPGDDGARGPKGYKGDPASQCGPPGPKGEPGSPGYQGRTGVPGEKGFPGDEGPRGPPGRPGQPGSFGPPGCPGDPGMPGLKGHPGEVGDPGPRGDAGDFGRPGPAGVKGPLGSPGLNGLHGLKGEKGTKGASGLLEMGPPGPMGMPGQKGEKGDPGSPGISPPGLPGEKGFPGPPGRPGPPGPAGAPGRAAKGDIPDPGPPGDRGPPGPDGPRGVPGPPGSPGNVDLLKGDPGDCGLPGPPGSRGPPGPPGCQGPPGCDGKDGQKGPMGLPGLPGPPGLPGAPGEKGLPGPPGRKGPVGPPGCRGEPGPPADVDSCPRIPGLPGVPGPRGPEGAMGEPGRRGLPGPGCKGEPGPDGRRGQDGIPGSPGPPGRKGDTGEAGCPGAPGPPGPTGDPGPKGFGPGSLSGFLLVLHSQTDQEPACPVGMPRLWTGYSLLYMEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLSSAAPLPMMPLSEEEIRSYISRCAVCEAPAQAVAVHSQDQSIPPCPRTWRSLWIGYSFLMHTGAGDQGGGQALMSPGSCLEDFRAAPFVECQGRQGTCHFFANEYSFWLTTVNPDLQFASGPSPDTLKEVQAQRRKISRCQVCMKHS