wanglab/gogpt-training-data huggingface dataset:
Protein: Copper chaperone for superoxide dismutase, chloroplastic/cytosolic (AtCCS) (Superoxide dismutase copper chaperone) (Q9LD47)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Copper chaperone for the superoxide dismutases CSD1, CSD2 and CSD3. Binds copper ions and delivers them specifically to CSDs. Is required for assistance in CSDs disulfide bond formation and thereby activation of CSDs. May be involved in the negative regulation of heat stress-responsive genes and thermotolerance.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:15848163}. Cytoplasm, cytosol {ECO:0000269|PubMed:15848163}. Note=It is unclear whether the chloroplastic and cytosolic proteins result from 2 different transcripts or from alternative translation initiation from the same transcript. {ECO:0000269|PubMed:16126858}.
Interaction partners:
- Superoxide dismutase 2, chloroplastic
- Superoxide dismutase 1
- Superoxide dismutase 3
- Copper-transporting ATPase RAN1
- Probable copper-transporting ATPase HMA5
- Putative cadmium/zinc-transporting ATPase HMA4
- Probable cadmium/zinc-transporting ATPase HMA1, chloroplastic
- Cadmium/zinc-transporting ATPase HMA2
- Copper-transporting ATPase PAA1, chloroplastic
- Putative inactive cadmium/zinc-transporting ATPase HMA3
Sequence:
MASILRSVATTSAVVAAASAIPIAIAFSSSSSSSSTNPKSQSLNFSFLSRSSPRLLGLSRSFVSSPMATALTSDRNLHQEDRAMPQLLTEFMVDMTCEGCVNAVKNKLETIEGIEKVEVDLSNQVVRILGSSPVKAMTQALEQTGRKARLIGQGVPQDFLVSAAVAEFKGPDIFGVVRFAQVSMELARIEANFTGLSPGTHSWCINEYGDLTNGAASTGSLYNPFQDQTGTEPLGDLGTLEADKNGEAFYSGKKEKLKVADLIGRAVVVYKTDDNKSGPGLTAAVIARSAGVGENYKKLCSCDGTVIWEATNSDFVASKV
Protein: Delta(12)-fatty-acid desaturase (Fatty acid desaturase 2) (EC 1.14.19.22) (EC 1.14.19.6) (Omega-6 fatty acid desaturase, endoplasmic reticulum) (P46313)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: ER (microsomal) omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. Delta(12)-desaturase with regioselectivity determined by the double bond (delta(9) position) and carboxyl group of the substrate. Can use both 16:1 and 18:1 fatty acids as substrates. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine (PC) and, possibly, other phospholipids. Very low constitutive hydroxylation activity. Required for desaturation of fatty acids present in extraplastidial membranes, including mitochondria. Required for salt tolerance during seed germination and early seedling growth.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14690501, ECO:0000305|PubMed:7907506}; Multi-pass membrane protein {ECO:0000255}. Microsome membrane {ECO:0000269|PubMed:1730697}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- 3-ketoacyl-CoA synthase 18
- Oleoyl-acyl carrier protein thioesterase 1, chloroplastic
- Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic
- Palmitoyl-acyl carrier protein thioesterase, chloroplastic
- Phospholipid:diacylglycerol acyltransferase 1
- Diacylglycerol O-acyltransferase 3
- Stearoyl-[acyl-carrier-protein] 9-desaturase 7, chloroplastic
- Oleoyl-acyl carrier protein thioesterase 2, chloroplastic
- Phospholipid-transporting ATPase 10
- Beta-ketoacyl-[acyl-carrier-protein] synthase III, chloroplastic
Sequence:
MGAGGRMPVPTSSKKSETDTTKRVPCEKPPFSVGDLKKAIPPHCFKRSIPRSFSYLISDIIIASCFYYVATNYFSLLPQPLSYLAWPLYWACQGCVLTGIWVIAHECGHHAFSDYQWLDDTVGLIFHSFLLVPYFSWKYSHRRHHSNTGSLERDEVFVPKQKSAIKWYGKYLNNPLGRIMMLTVQFVLGWPLYLAFNVSGRPYDGFACHFFPNAPIYNDRERLQIYLSDAGILAVCFGLYRYAAAQGMASMICLYGVPLLIVNAFLVLITYLQHTHPSLPHYDSSEWDWLRGALATVDRDYGILNKVFHNITDTHVAHHLFSTMPHYNAMEATKAIKPILGDYYQFDGTPWYVAMYREAKECIYVEPDREGDKKGVYWYNNKL
Protein: Kinase like protein (Protein kinase superfamily protein) (Putative kinase) (O23334)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEKKSEEDGNNTTKEKIFRADKIDLKSLDRQLEKHLSRVWSRNLEVNPKAKEEWEIDLAKLETSNVIARGTYGTVYKGIYDGQDVAVKVLDWEDDGNETTAKTATNRALFRQEVTVWHKLNHPNVTKFVGASMGTTNLNIRSADSKGSLPQQACCVVVEYLPGGTLKQHLIRHKSKKLAFKAVIKLALDLARGLSYLHSEKIVHRDVKTENMLLDAQKNLKIADFGVARVEALNPKDMTGETGTLGYMAPEVIDGKPYNRRCDVYSFGICLWEIYCCDMPYPDLSFVDVSSAVVLHNLRPEIPRCCPTALAGIMKTCWDGNPQKRPEMKEVVKMLEGVDTSKGGGMIPEDQSRGCFCFAPARGP
Protein: T-complex protein 1 subunit delta (Q6PH46)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- T-complex protein 1 subunit gamma.
- T-complex protein 1 subunit eta
- T-complex protein 1 subunit theta
- Chaperonin-containing TCP1, subunit 6A
- T-complex protein 1 subunit epsilon
- Tcp1 protein.
- Chaperonin-containing TCP1, subunit 2
- Chaperonin-containing TCP1, subunit 2
- Prefoldin subunit 5
- MKKS centrosomal shuttling protein
Sequence:
MPEAVVAASGIKNKGSAYVDRDKPAQIRYSNINAGKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAAKMMVELSKAQDIEAGDGTTSVVVIAGALLDACAKLLQKGIHPTIISESFQKAVDKGVEVLTSISTPLLLSDRESLLNSASTSLCSKVVSQNSSLLAPMSVDAVMKVIDPATATSVDLRDINVVKKLGGTIDDCELVDGMVLTQRVASTGVSRVEKAKIGLIQFCLSPPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQVKKAGCTVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREEIEFICKTIGTKPIAHIDQFTPEMLGSAELVEEVSLDGSGKLVKITGCASPGKTVSIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLAEYARSLGGMEAYCVRAYADALEVIPSTLAENAGLNPISTVTELRNRHAQGETTAGINVRKGGISNILEELVVQPLLVSISALTLATETVRSILKIDDLVNTR
Protein: Protein DEPP1 (Decidual protein induced by progesterone) (Fasting-induced gene protein) (FIG) (Q9NTK1)
Organism: Homo sapiens (Human)
Function: Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24530860, ECO:0000269|PubMed:25261981}. Peroxisome {ECO:0000269|PubMed:25261981}. Mitochondrion {ECO:0000269|PubMed:25261981}. Note=May localize to aggresomes (PubMed:24530860). {ECO:0000269|PubMed:24530860}.
Interaction partners:
- Cornulin
- Repetin
Sequence:
MRSRLLLSVAHLPTIRETTEEMLLGGPGQEPPPSPSLDDYVRSISRLAQPTSVLDKATAQGQPRPPHRPAQACRKGRPAVSLRDITARFSGQQPTLPMADTVDPLDWLFGESQEKQPSQRDLPRRTGPSAGLWGPHRQMDSSKPMGAPRGRLCEARMPGHSLARPPQDGQQSSDLRSWTFGQSAQAMASRHRPRPSSVLRTLYSHLPVIHEL
Protein: Raptor N-terminal CASPase-like domain-containing protein (Q387I9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- ethanolamine kinase
- Ras-family member, GTP-binding protein, putative
- Small GTPase, putative
- Choline/ethanolamine kinase, putative
- non-specific serine/threonine protein kinase
- PI3K/PI4K catalytic domain-containing protein
- non-specific serine/threonine protein kinase
- Serine/threonine-protein kinase TOR
- Serine/threonine-protein kinase TOR
Sequence:
MKRGTRIITPCRVVFSRLPIQSIMRNRRRVSVTSSTSALVNELLAAFAPHHLPSLSTGFDMGRSSEDIQDIDGHREWYRGGRGRRCPRLLLILCLNNGNDPPDFSRIDPCARLECWEEPYIARMPHIVTGGGSERIAALLQRQYHSQLQGAVSSMAVEVELEDAKKRMANIRLDAREELVVFHYNGHGMPRATGYGEIWMFDKKRTSYVPLSLAEMAEHLSSPTLYVFDCNSAGSLLKFWCEERLHETRPDDMFICACSAGAFLPLNPQLPADVLTSSLTTPLRMASEWYINFSHRKHLLPHVTAEMIRNVPGDISDERTPLGELQLILTAVTDIVAWCIVPSPLYCKLFRRDETTMVLFRNFLLADRLLREVGCVPQTHPPIPEEAHLHHAWDLWDYTLENVICQLPDLLTRDLVLNPNYTYKPSTFFEDQLMSFEVWLKSGDMREQPEELPSVLSALKRPQCCVAALTLLVTYLDSDVIAGKWAILCGILTHITSLLRNQELFLMASVLWMQVLRVDESLGTSELIKRRLGNRFIKVLTLTEKDLCVQTVERGQVAPLRALNNVNRRVGRGDTQASGNNSACPAQISCYLMEGVDLGRCKEIACYLFCQLLRHGGTTACVECWNGGLLNAAASLLESPSAEVRSWSCLVLAQLLFSLQFAKDFVSRKCTTHVGLFTHLLQDKSPIVRGSCVTLLSSLIGFRVSEAPGEHAVRRLQVEKTLLIKLRGMVYDASVIVRQELVLFACTVLFHYGPFLPSLQDTTAKTRYVVYMQEVGQCFPSWFLDEPDVQVKSMLNTSRPTANRCFNSKSVFENAPCAPADLTEPPWTPLAMDDIRSEDLPVLRGMVHDAALMLFSLYQACDKVMVTAALEKLGDNKRPESQRFTNESLRSMSSVVSANSTHFMSEAERARVTRNADNMQRIVLDLHDQKTEPPSMCTTAANRTRSLAVDGHSATYNANHSSGIPGAGDEKVNLDLVYAPHQILQSLLPCDQVICSTLRVLETAMVIATRNQYIYHVSYESYSVQETVHSFQVHLASPLHDILVINDASEQAGLLLVNQRGGYSLIRDCWEKTQGSPVEVAVFSACPPQRTVDIKSAYRSHNANLIYGGPIGYGGGTEIHILSLDEEQVIQQLKVSGDPTITSLSAHTTGRAVFAGCSDGLVRYYDDRQKQGFLGAVGSLRCGTTSYSPMEAVLGAGPVERDVAQLTIAMASRSAVYLYDTRKVNAPYLEVRVNELCDAVVPSSAAKPPPIRAFDAGTHTGMLGVLFADGTYTALNARGRPILRRAIQTRVQGPIFPGSLAVHPLRRVMSVGGEILVVH
Protein: Ribonuclease Z (RNase Z) (EC 3.1.26.11) (tRNA 3 endonuclease) (tRNase Z) (P36159)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Mitochondrial nuclease
- CCA tRNA nucleotidyltransferase, mitochondrial
- Exosome complex exonuclease RRP6
- ATP-dependent RNA helicase SUV3, mitochondrial
- Exportin-T
- Glucose-6-phosphate 1-epimerase
- Ribonuclease 3
- tRNA-splicing endonuclease subunit SEN34
- RNA exonuclease 1
- Multisite-specific tRNA:
Sequence:
MFTFIPITHPTSDTKHPLLLVQSAHGEKYFFGKIGEGSQRSLTENKIRISKLKDIFLTGELNWSDIGGLPGMILTIADQGKSNLVLHYGNDILNYIVSTWRYFVFRFGIDLNDHIMKDKEVYKDKIIAVKSFNVLKNGGEDRLGVFDSFQKGVLRSIVAKMFPKHAPTDRYDPSSDPHLNVELPDLDAKVEVSTNYEISFSPVRGKFKVEEAIKLGVPKGPLFAKLTKGQTITLDNGIVVTPEQVLENERHFAKVLILDIPDDLYLNAFVEKFKDYDCAELGMVYYFLGDEVTINDNLFAFIDIFEKNNYGKVNHMISHNKISPNTISFFGSALTTLKLKALQVNNYNLPKTDRVFSKDFYDRFDTPLSRGTSMCKSQEEPLNTIIEKDNIHIFSQNKTVTFEPFRMNEEPMKCNINGEVADFSWQEIFEEHVKPLEFPLADVDTVINNQLHVDNFNNSAEKKKHVEIITLGTGSALPSKYRNVVSTLVKVPFTDADGNTINRNIMLDAGENTLGTIHRMFSQLAVKSIFQDLKMIYLSHLHADHHLGIISVLNEWYKYNKDDETSYIYVVTPWQYHKFVNEWLVLENKEILKRIKYISCEHFINDSFVRMQTQSVPLAEFNEILKENSNQESNRKLELDRDSSYRDVDLIRQMYEDLSIEYFQTCRAIHCDWAYSNSITFRMDENNEHNTFKVSYSGDTRPNIEKFSLEIGYNSDLLIHEATLENQLLEDAVKKKHCTINEAIGVSNKMNARKLILTHFSQRYPKLPQLDNNIDVMAREFCFAFDSMIVDYEKIGEQQRIFPLLNKAFVEEKEEEEDVDDVESVQDLEVKLKKHKKN
Protein: GDP-fucose transporter 1 (GDP-mannose transporter GONST4) (Protein GOLGI NUCLEOTIDE SUGAR TRANSPORTER 4) (Q84L08)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as the major nucleotide-sugar transporter for the import of GDP-Fucose into the Golgi lumen. Transports GDP-Fucose in a strict counter-exchange mode. Is required for proper plant growth and development. Acts also as a GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:15480787, ECO:0000269|PubMed:27381418}; Multi-pass membrane protein {ECO:0000269|PubMed:15480787}.
Interaction partners:
- GDP-mannose transporter GONST5
- UDP-galactose/UDP-glucose transporter 1
- UDP-xylose transporter 3
- Probable sugar phosphate/phosphate translocator At5g25400
- Probable sugar phosphate/phosphate translocator At4g32390
- UDP-rhamnose/UDP-galactose transporter 2
- GDP-mannose 4,6 dehydratase 2
- UDP-xylose transporter 2
- UDP-xylose transporter 1
- UDP-galactose/UDP-glucose transporter 2
Sequence:
MSSSRFDSNKQLTTSSLVIGYALCSSLLAVINKLAITYFNYPGLLTALQYLTCTVAVYLLGKSGLINHDPFTWDTAKKFLPAAIVFYLAIFTNTNLLRHANVDTFIVFRSLTPLLVAIADTVFRSQPLPSRLTFLSLVVILAGAVGYVATDSSFTLTAYSWALAYLVTITTEMVYIKHMVSNIKLNIWGLVLYNNLLSLMIAPVFWFLTGEFTEVFAALSENRGNLFEPYAFSSVAASCVFGFLISYFGFAARNAISATAFTVTGVVNKFLTVVINVLIWDKHATPVGLVCLLFTICGGVGYQQSVKLDKPIEKVSEKDSEKGEEDEELTQLVPGKLASVV
Protein: RAS p21 protein activator 3 (Ras GTPase-activating protein 3 isoform X4) (E7F916)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Amine oxidase.
Sequence:
MAVEEEGLRVFQSVKIKIGEAKNIPPYPGPNKMRDCYCTVNLDQEEVFRTKTIEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSSIGKVAVKKEDLQKYHGKDHWFPLQPVCADSEVQGKVHLELRLSELITDSGGLCHKLATRVLECQDLPIVNGQCDPYAAVSLLGPSRSEAKKTKVKRKNNNPQFDEIFFFEVTKPLSFTKRQFDVEEDDVDKLALKVDLWNASNLKFGDEFLGEVRVPLKVLGQAGVHDAWYFLQPRDNGHKSVKADELGSLRLNIVYTEDHVFPTEHYNPLRDLLLQSAHVQPVSASAAHILGEVCREKQEAAVPLVRLFLHYGKIVPFLSAIAHAEISRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLRVTLKPIIDEICSDHKPCEIDPVKLKESENLDTNRENLRQYVDRIFSVITSSGVSCPTVMCDIFFSLRESAASRFQVDADVRYTAVSSFIFLRFFAPAILSPNLFHLRPHHPDPCTSRTLTLISKTIQTLGSLAKSKSANFKESYMAAFYDYFNEQKYADAVKNFLDLISSSARWDQKSIETPIMLKEGFMIKRAQGRNRFGLKNFKKRWFRLTNHEFTYHKTKGEGALCSIPIENILAVERLEEESFKMKNMFQVIQPERALYIQANNCVEARDWIDILTKVSQCNRKRLSTFHPSAFLNGHWLCCKLSADTAPGCTPCTGGLPANIQLDVDGDRETERIYSLYSTYMSKLVKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLRLVISAVQTLEQQHTQYKRDKFRKTKYGSQEHPIGDQSFQCYIRQQSESSTYSI
Protein: Filamin A-interacting protein 1-like (130 kDa GPBP-interacting protein) (90 kDa GPBP-interacting protein) (Protein down-regulated in ovarian cancer 1) (DOC-1) (Q4L180)
Organism: Homo sapiens (Human)
Function: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18794120}. Membrane {ECO:0000269|PubMed:18794120}. Nucleus {ECO:0000269|PubMed:18794120}.
Interaction partners:
Sequence:
MRSRGSDTEGSAQKKFPRHTKGHSFQGPKNMKHRQQDKDSPSESDVILPCPKAEKPHSGNGHQAEDLSRDDLLFLLSILEGELQARDEVIGILKAEKMDLALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNGRRISDPQVFSKEVQTEAVDNEPPDYKSLIPLERAVINGQLYEESENQDEDPNDEGSVLSFKCSQSTPCPVNRKLWIPWMKSKEGHLQNGKMQTKPNANFVQPGDLVLSHTPGQPLHIKVTPDHVQNTATLEITSPTTESPHSYTSTAVIPNCGTPKQRITILQNASITPVKSKTSTEDLMNLEQGMSPITMATFARAQTPESCGSLTPERTMSPIQVLAVTGSASSPEQGRSPEPTEISAKHAIFRVSPDRQSSWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVASPVRPASPSAPLQDNRTQGLINGALNKTTNKVTSSITITPTATPLPRQSQITVEPLLLPH
Protein: N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase (EC 5.1.3.26) (GlcNAc-P-P-Und 4-epimerase) (Q8X7P7)
Organism: Escherichia coli O157:H7
Function: Involved in biosynthesis of the repeating tetrasaccharide unit of the O-antigen. Catalyzes the reversible epimerization of the hydroxyl group at position C4 of undecaprenyl pyrophosphate-N-acetylglucosamine (UndPP-GlcNAc) to yield undecaprenyl pyrophosphate-N-acetylgalactosamine (UndPP-GalNAc).
Subcellular location: Cell membrane {ECO:0000269|PubMed:19923219}.
Interaction partners:
- UTP--glucose-1-phosphate uridylyltransferase
- UTP--glucose-1-phosphate uridylyltransferase
- ECA polysaccharide chain length modulation protein
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS14
- Colanic acid biosynthesis protein WcaM
- Small ribosomal subunit protein uS12
- Colanic biosynthesis UDP-glucose lipid carrier transferase
- Colanic biosynthesis UDP-glucose lipid carrier transferase
- Small ribosomal subunit protein uS3
Sequence:
MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQIGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVKNIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIRPTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGYEVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAVSSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE
Protein: Probable xylan O-acetyltransferase 10 (EC 2.3.1.-) (Protein trichome birefringence-like 5) (OsTBL5) (Q84TW8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan. Possesses extremely low activity in vitro.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q2QYU2}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MMKPQHGGMAGHGGGRTRSPFLTSYALTLAFITFVSVLYFKDFSSTLHQPFLTRPPPHRRQIARPRAPSHHHGGGSSSGGGDVVPPFAVGAAAAAGCDVGVGEWVYDEAARPWYEEEECPYIQPQLTCQAHGRPDTAYQHWRWQPRGCSLPSFNATLMLEMLRGKRMMFVGDSLNRGQYVSLVCLLHRSIPESSKSMETFDSLTVFRAKNYNATIEFYWAPFLAESNSDDAVVHRIADRIVRGTALEKHARFWKGADILVFNSYLWWMTGQKMKILQGSFEDKSKDIVEMETEEAYGMVLNAVVRWVENNMNPRNSRVFFVTMSPTHTRSKDWGDDSDGNCYNQTTPIRDLSYWGPGTSKGLMRVIGEVFSTSKVPVGIVNITQLSEYRKDAHTQIYKKQWNPLTPEQIANPKSYADCTHWCLPGLQDTWNELLYSKLFFP
Protein: CG13350 (Q2XY08)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
LRYAHTNGYTGLLYTPRGEFIITCGTDGDIRHWTCISDDDPRSSCLGEFVMCIAHTGTRLLASTDRNTIHAYTFPEMDSDGILMRFTAPATCLKVSGGYTAAGSEDTTIKVLKGDTAGNETVLEGHTGPILALDLFAERKLLVSVAGDGQLKVWNFEEGKELKTIGGLPKVNSFESASLYGTPHFEPQSGELLAYAVDNEIVVLNTANWEVAFKLRDDSVSSNYSCCQFSPNGERLAAGTTKGEVSIFDVKKRKAVTVEIPPSDCNAITCLAWNLSGEVEVAFCDATGQLGTVFLGDAVDTGNGDGLVDDQAELLGDDYEFEAGDDVDTAADDGDGVSLEQLKRKVMNFADPVDHDDASNQSLDSSSRTVPAPVAPQIKLFKQQTAFQPSATPADLEHRYMAWNDVGIVTAHVEPSGDSSIDVEFHDASIHHALHISNYNQHNLASVSSGALALASNESSKLVVIALAAAGNKEWSLSLPDCESAEAVVATRFLVAVATSSSFLRIFTVMGTQREVLTIPGPVVAIAGHEHSLMVVYHSSAPSQTQQHLAAMLVNINGLSLRQEYLPVPLTPGRQLTWFGYSDTGSPSIADNMGLLQLYRRSSNAWFPICDTMKQSTSVSHNFFVVAVSEKRQIVQAVLCRGTSYPMTNPRPMLQELRMQIPLCDVEVEKSELEDALLRSSLMQMDGAEKMQKETAIKLFALACSSECETRARELIESIACTDLLQLAVKYATKRGRIHLSDRLCELLPQLEAVQEARKQQTLLGASGIAATIVLPMTPTSASQSGPKPKAIELSSAKRGTLKRLVNSPNMFKAAAASAASRPSTPDITPSPLDTQENIFGESESEVPMGKATDHRSPLNSVNPFAMKRKLGDTGVIF
Protein: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) (Q582B0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion {ECO:0000256|RuleBase:RU365024}.
Interaction partners:
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Phosphatidate cytidylyltransferase
Sequence:
MLFLLAYALVFGTSLLLAFRLFSLSGSVQTSTCHSNGTLFHALDNKVTVGGRTRGASSVVTDGPQAEMLRFLGETCCTLPARGKDLRVLAGPKQFFSELLRQISAAQHRIVLSALYIGDGPLARQLVTALRNRVSKARSDKKALDVCILLDYNRMHVRQNLKTVAELLNLQSEAASPGADSAVNVRLFLFQSPCRWNWLVAPFGRAREALGVQHTKIFCFDNCQTILTGANLSDDYFDTRVDRYLAVHDNPHVAAWFSGLVDALCALSYPVGIHKECNTNAGSATVAGCGDTKKWGQNANSSSGEFVVHAGSNLTIFPNMAGVDPSTQWYEFCEVAERRLRDFAHSSGAVAAEAWQVEQHPEMEDEATGHYDTLLFPTMQCARANIFHDSFIVQMLLRMAPRSTHIYLASPYLNMYGHFVDELLASSSPYDFITASVSTNGWYGSKGFARYIPYFYLQLQRAFRYLMKEYKCAHRIRLHEFSAEGKTYHAKGLWFMKDQKQGGAPVGRVGISSACAGGANNNDVVNCEETWDHVGEPYLVSYGSTNYGSRSVHRDVEVEVFLYTTNEGLRGALRQDLISLLQESTSVSDERFVGNGEGRFQPLVSLMAQMGQDLL
Protein: Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Q9BWU0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:15764369}. Cytoplasm {ECO:0000269|PubMed:15764369}. Note=Mainly nuclear. Small amounts are found in the cytoplasm.
Interaction partners:
- tRNA N6-adenosine threonylcarbamoyltransferase
- Band 3 anion transport protein
- U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
Sequence:
MADILSQSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEVQKEGPTALQDSNSGEPDIPPPQPDCGDFRSLQEEQSRPPTAVSSPGGPARAPPYQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPEGQSGDGRTHLNDKYGY
Protein: Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) (P41566)
Organism: Sus scrofa (Pig)
Function: Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Subcellular location: Mitochondrion.
Interaction partners:
- Isocitrate dehydrogenase subunit alpha, mitochondrial
- Isocitrate dehydrogenase subunit beta, mitochondrial
- Aconitate hydratase, mitochondrial
- Isocitrate dehydrogenase, mitochondrial
- Isocitrate dehydrogenase
- 2-oxoglutarate dehydrogenase complex component E1
- Cytoplasmic aconitate hydratase
- 2-oxoglutarate dehydrogenase-like, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- Glutamate dehydrogenase 1, mitochondrial
Sequence:
FSQQTIPPSAKYGGILTVTMSPGDGDGPELMLTVXXXXXSACVPVDFEEVVVSSNADEEDIRTSLDLYANVIHCKLGDGLFLQCCKNIANPTATLLASCMMLDHLK
Protein: Ferripyoverdine receptor (P48632)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Receptor for the siderophore ferripyoverdine.
Subcellular location: Cell outer membrane {ECO:0000255|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU01360}.
Interaction partners:
- FpvR
- Pyoverdine biosynthesis protein PvdE
- L-ornithine N
- phosphoribosylglycinamide formyltransferase 1
- Sigma factor PvdS
- FpvI
- Pyocin-S2
- PepSY domain-containing protein
- Pyoverdine synthetase D
- Protein TonB
Sequence:
MPAPHGLSPLSKAFLMRRAFQRRILPHSLAMALSLPLAGYVQAQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTGASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF
Protein: Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25) (P42331)
Organism: Homo sapiens (Human)
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Interaction partners:
Sequence:
MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
Protein: Conserved protein (O06418)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- o-succinylbenzoate synthase
- Putative non-heme bromoperoxidase BpoC
- UPF0045 protein Rv1898
- Uncharacterized protein Rv0874c
- Probable acyl-CoA dehydrogenase FadE20
- Medium/long-chain-fatty-acid--CoA ligase FadD8
- GDP-mannose-dependent alpha-mannosyltransferase
- Probable conserved integral membrane protein
Sequence:
MADADLVMTGTVLTVDDARPTAEAIAVADGRVIAVGDRSEVAGLVGANTRVIDLGAGCVMPGFVEAHGHPLLEAVVLSDRFVDIRPVTMRDADDVVAAIRGEVARRGPAGAYLVGWDPLLQSGLGEPTLTWLDSLAPNGPLVIIHNSGHKAYFNSHAAWLNGLTRDTADPKGAKYGRDGNGELDGTAEEIGAILPLLAGVADPSNFGAMLRAECARLNRAGLTTCSEMAFDPGYRPMVEAVRAELTVRLCTYEISNARMCTDATPGQGDDMLRQVGIKIWVDGSPWVGNIDLTFPYLDTPATRAIGVPPGSRGCANYTREQLAEIVGAYFPRGWQIACHVHGDGGVDTILDVYEEALRRNPRDDHRLRLEHVGAIRPDQLRRAAELGVTCSIFVDQIHYWGDVIVDDLFGAQRGSRWMPAGSAVAAGMRISLHNDPPVTPEEPLRNISVAATRVAPSGRVLAPEERLTVEQAIRAQTIDAAWQLFAEDAIGSLQVGKYADMVVLSADPRTVPPEQIADLAVRATFLAGRQVYRR