wanglab/gogpt-training-data huggingface dataset:
Protein: Serine/threonine-protein kinase AtPK2/AtPK19 (EC 2.7.11.1) (Ribosomal-protein S6 kinase homolog 2) (Q39030)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Downstream effector of TOR signaling pathway. May be involved in adaptation of plant to cold or high-salt conditions. Mediates the phosphorylation of MRFs (e.g. MRF1).
Interaction partners:
- Small ribosomal subunit protein eS6z
- Small ribosomal subunit protein eS6y
- Serine/threonine-protein kinase TOR
- 3-phosphoinositide-dependent protein kinase 1
- 3-phosphoinositide-dependent protein kinase 2
- Regulatory-associated protein of TOR 2
- Peptidyl-prolyl cis-trans isomerase FKBP12
- Regulatory-associated protein of TOR 1
- Transmembrane protein
- Uncharacterized protein
Sequence:
MVSSQCSVANKNQTGKPFQKHLSLSISPPKSVLGDNLELQFSDVFGPMPEANSEEACDVAYDEPAVVYSRSHSLVGPSLVVSHSLKMNKLTLRETEDSVDLVECVEGESIKENDEFSGNDDTDSEKSPEEVSGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFDKCWTDMSVLDSPASSPNSDAKANPFTNFTYVRPPHSFLHRTTSNL
Protein: CCR4-NOT transcription complex subunit 9 (Cell differentiation protein RQCD1 homolog) (Rcd-1) (EPO-induced protein FL10) (Q9JKY0)
Organism: Mus musculus (Mouse)
Function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation. Required for retinoic acid-induced differentiation of F9 teratocarcinoma cells. Does not bind DNA by itself. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors. May play a role in cell differentiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:15209511}. Cytoplasm, P-body {ECO:0000269|PubMed:20133598}. Note=NANOS2 promotes its localization to P-body. {ECO:0000269|PubMed:20133598}.
Interaction partners:
- CCR4-NOT transcription complex subunit 7
- CCR4-NOT transcription complex subunit 1
- CCR4-NOT transcription complex subunit 4
- CCR4-NOT transcription complex subunit 2
- CCR4-NOT transcription complex subunit 3
- CCR4-NOT transcription complex subunit 8
- CCR4-NOT transcription complex subunit 11
- CCR4-NOT transcription complex subunit 6
- CCR4-NOT transcription complex subunit 10
- CCR4-NOT transcription complex subunit 6-like
Sequence:
MHSLATAAPVPTALAQVDREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ
Protein: Mpv17-like protein 2 (Q8VIK2)
Organism: Mus musculus (Mouse)
Function: Required for the assembly and stability of the mitochondrial ribosome (By similarity). Is a positive regulator of mitochondrial protein synthesis (By similarity).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q567V2}.
Interaction partners:
- Mitochondrial inner membrane protein Mpv17
- Mpv17-like protein
Sequence:
MALGGWRWARKALAAGRPLFQGRALLLTNTLGCGVLMAAGDGARQVWEVRARPGQRFSARRSASMFAVGCSMGPFLHFWYLWLDRLLPASGLRSLPSVMKKVLVDQTVASPILGVWYFLGLGSLEGQTLEESCQELRAKFWDFYKADWCVWPAAQLVNFLFIPSHFRVTYINGLTLGWDTYLSYLKYWVPEPLQTPGCAD
Protein: Squamosa promoter-binding-like protein 13B (P0DI11)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- AP2-like ethylene-responsive transcription factor SNZ
- AP2-like ethylene-responsive transcription factor TOE2
- AP2-like ethylene-responsive transcription factor TOE3
- AP2-like ethylene-responsive transcription factor SMZ
- Ethylene-responsive transcription factor RAP2-7
- Selenium-binding protein 2
Sequence:
MDWNFKLSSGYLSGFDQEPDLSPMDGSISFGGSSQSKADFSFDLKLGRNIGNSSSVFGDTEQVISLSKWKDSALAKPEGSRSSSSKRTRGNGVGTNQMPICLVDGCDSDFSNCREYHKRHKVCDVHSKTPVVTINGHKQRFCQQCSRFHALEEFDEGKRSCRKRLDGHNRRRRKPQPEHIGRPANFFTGFQGSKLLEFSGGSHVFPTTSVLNPSWGNSLVSVAVAANGSSYGQSQSYVVGSSPAKTGIMFPISSSPNSTRSIAKQFPFLQEEESSRTASLCERMTSCIHDSDCALSLLSSSSSSVPHLLQPPLSLSQEAVETVFYGSGLFENASAVSDGSVISGNEAVRLPQTFPFHWE
Protein: Regulatory associated protein of MTOR, complex 1 (A0A8I6AHQ2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MESEMLQSPLMGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNCIQLAACEAHELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPGRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWLTMGVENRSPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPVRTEPHSSPTACMSPVHTRGSCLQGNLIAICLEQLSDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLINDGSPMVRKELVVALSHLVVQYESNFCTVALQFMEEEKNYPLPSPAATEGGSLTPVRDSPCTPRLRSVSSYGNIRAVTTARNLNKSLQNLSLTEESGSSVAFSPGNLSTSSSASSTLGSPENEEYILSFETIDKMRRVSSYSALNSLIGVSFNSVYTQIWRVLLHLAADPYPDVSDLAMKVLNSIAYKATVNARPQRILDTSSLTQSAPASPTNKGMHIHQVGGSPPASSTSSCSLTNDVAKQTVSRDLPSSRPGTAGPTGAQYTPHSHQFPRTRKMFDKGPDQTTDDADDAAGHKSFICATMQTGFCDWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNTRVRKQAQQVIQKGKCTAPPRGAGLLSSPPQPPSTVCAALVDQSTDCFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQDCSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDRETKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWVVKAYLQKHPEGHIVSVSVNGDVRFFDPRMPESVNVMQIVKGLTALDIHPQANLIACGSMNQFTAIYNGNGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGSNDYYISVYSVEKRVR
Protein: Ribosome binding protein 1 (F8W7S5)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
Sequence:
MVFNEGEAQRLIEILSEKAGIIQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAEDGSSSKEGTSV
Protein: Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3) (Q9H1J1)
Organism: Homo sapiens (Human)
Function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.
Subcellular location: Nucleus {ECO:0000269|PubMed:11163187}. Cytoplasm {ECO:0000269|PubMed:11163187}. Note=Shuttling between the nucleus and the cytoplasm. {ECO:0000269|PubMed:11163187}.
Interaction partners:
- Protein mago nashi homolog
- Nonsense-mediated mRNA decay factor SMG5
- RNA-binding protein 8A
- Eukaryotic initiation factor 4A-III
- Protein CASC3
- Regulator of nonsense transcripts 1
- Nuclear RNA export factor 1
- RNA-binding protein with serine-rich domain 1
- Regulator of nonsense transcripts 2
- Serine/arginine repetitive matrix protein 1
Sequence:
MRSEKEGAGGLRAAVAARGPSGREKLSALEVQFHRDSQQQEAETPPTSSSGCGGGAGKPREEKRTALSKVVIRRLPPGLTKEQLEEQLRPLPAHDYFEFFAADLSLYPHLYSRAYINFRNPDDILLFRDRFDGYIFLDSKGLEYPAVVEFAPFQKIAKKKLRKKDAKTGSIEDDPEYKKFLETYCVEEEKTSANPETLLGEMEAKTRELIARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRIKLLKKPEKGEEPTTEKPKERGEEIDTGGGKQESCAPGAVVKARPMEGSLEEPQETSHSGSDKEHRDVERSQEQESEAQRYHVDDGRRHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPGEAMERLGRAQRCDDSPAPRKERLANKDRPALQLYDPGARFRARECGGNRRICKAEGSGTGPEKREEAE
Protein: Aerolysin-like protein (Jacalin-type lectin domain-containing protein 5) (Q5CZR5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Pore-forming protein which might play a role in host defense. Exists as an antiparallel dimer in solution. Can also assemble into an octameric pore-like structure spanning the cell membrane. Oligomerization may be triggered by binding of the jacalin-type lectin domain to high-mannose cell-surface proteoglycans, and also requires a low pH environment. In vitro, shows high binding affinity for S.cerevisiae mannan and human HIV virus glycoprotein gp120.
Subcellular location: Cell membrane {ECO:0000305|PubMed:26711430}.
Interaction partners:
- Transcobalamin beta b
- Complement component C9
- Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
- PAN2-PAN3 deadenylation complex catalytic subunit PAN2
- ferroxidase
- U3 small nucleolar RNA-interacting protein 2
Sequence:
MTYPTNLEIIGGQGGSSFSFTGENNGASLEKIWVWVGGWQIKAVRAWLSDGRDETFGVPSGSHQEYVFTPGECFTSLSLWGNGAGTRLGAIKFKTNKGGEFFAHMTSWGLKTEYPMDVGSGYCLGIVGRGGSDIDCMGFMFLNAVQSTVLTNVNYPTINQLIPKVATEEIKSVSFENKTSVKQEQKVETSKKVIKTSSWSMTKSFSSTFSVEVSAGIPEIAEVSTGFSISFGVESTHSLEQTDEKNETLTTTVEVPPKKKVDVHITIGRASFDLPYTGTVKITCKNGSVLQYETKGQYKGVAYTDIKVNTVEKDL
Protein: Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Q09028)
Organism: Homo sapiens (Human)
Function: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:10220405, ECO:0000269|PubMed:10866654, ECO:0000269|PubMed:14609955, ECO:0000269|PubMed:20523938, ECO:0000269|PubMed:28977666, ECO:0000269|PubMed:29499137, ECO:0000269|PubMed:30026490, ECO:0000269|PubMed:33283408, ECO:0000269|PubMed:8858152}. Chromosome, telomere {ECO:0000269|PubMed:30045876}. Note=Localizes to chromatin as part of the PRC2 complex. {ECO:0000269|PubMed:29499137}.
Interaction partners:
- Histone-binding protein RBBP7
- Paired amphipathic helix protein Sin3a
- Histone deacetylase complex subunit SAP30
- Polycomb protein EED
- Chromodomain-helicase-DNA-binding protein 3
- Histone H4
- Chromodomain-helicase-DNA-binding protein 4
- Polycomb protein SUZ12
- Chromatin assembly factor 1 subunit B
- Metastasis-associated protein MTA2
Sequence:
MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
Protein: Glucose-6-phosphatase catalytic subunit 1 (EC 3.1.3.9) (Glucose-6-phosphatase) (A2VD27)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MDTMHGFGVSSTQYLQTHYKDAQGWFLFVSFAADLRNTFFIFFPIWFHLKESVGIKLIWVAVIGDWLNLVFKWILFGERPYWWVHETSYYMNSSAPHIEQYPMTCETGPGSPSGHAMGAAGVYYTLVTSILAIMLSKGKKSTSNSLYLRGSLWTLFWTVQICVCLSRVFIAAHFPHQVFAGVISGMIVAEAFNRQKWIYSASLKNYFNVTLFLLSFAVGLYVLLKALGVDLLWTLEKAQKWCANPAWVHLDTTPFASLLRNMGTLFGLGLGLHSPLYTESKKSSNAFVRITCIIASLLLLHLFDSIKPPTHTAALFYLLSFCKSATVPLVTVSIIPYCLSGALGLQSKKQL
Protein: Carnosine dipeptidase 2 (J3QL02)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAALTTLFKYIDENQDRYIKPVQLQQPQRVSLECGNVTGASSPSRTPFQNPSLLLVHKQKLAKWVAIQSVSAWPEKRGEIRRMMEVAAADVKQLGGSVELVDIGKQKLPDGSEIPLPPILLGRLGSDPQKKTVCIYGH
Protein: Small ribosomal subunit protein RACK1 (Activated protein kinase C receptor homolog) (Guanine nucleotide-binding protein subunit beta-like protein) (P69103)
Organism: Trypanosoma brucei brucei
Interaction partners:
Sequence:
MAVAYEGQLTGHRGWVTSLACPQTPETATKVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTKGEALSEMAAGAPINQICFSPNRYWMCAATEKGIRIFDLENKDIIVELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVIRVWGVSENA
Protein: Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma) (O00505)
Organism: Homo sapiens (Human)
Function: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Recognizes NLSs of influenza A virus nucleoprotein probably through ARM repeats 7-9.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:34564892}. Nucleus {ECO:0000269|PubMed:34564892}.
Interaction partners:
- Importin subunit beta-1
- Importin subunit alpha-3
- Exportin-2
- Regulator of chromosome condensation
- Transcription factor p65
- Nuclear factor NF-kappa-B p105 subunit
- Importin subunit alpha-5
- Nuclear cap-binding protein subunit 2
- GTP-binding nuclear protein Ran
- E3 SUMO-protein ligase RanBP2
Sequence:
MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF
Protein: Protein CBR-EGL-20 (A8WV58)
Organism: Caenorhabditis briggsae
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- Protein CBR-LIN-17
- Protein CBR-CFZ-2
- Protein CBR-MOM-5
- Protein CBR-MIG-1
- Protein CBR-SFRP-1
- Protein-serine O-palmitoleoyltransferase porcupine
- receptor protein-tyrosine kinase
- receptor protein-tyrosine kinase
- Protein CBR-MIG-14
- Protein CBR-CWN-1
Sequence:
MQFSIFQLFLFVLLVYAQHIPLSGNQNSPQVPYNWLTLAFVGSNDYLPRPHYHSSDRDHFKELCRRLDGLNPNQQAMCAENPFSIPFVARGVREAIRECENKFKFERWNCSSRDEVTETRHGKFQDILGKTLRSSNKEAAFLSAIMAASIVHSITKGCNTGNLTECGCDSKPGMQRYQADSDSAMSRDQFSWGGCSDNVPYGIRYARRFLDEWEVQQFEETKNVAHLVRRHNNFVGREAIAQNIRRQCRCHGVSGSCEFKTCWLQMQKFSQVSDLLKKRYDHFAVQVELEDVTRKATKRLRRKERTERKIPLRGNEMAYVHRSPSYCERNLTAGILGTSGRECIHNSYSSESCDLLCCGRGYNTRLEIRQTQCECKFVWCCEVKCKTCTEEVAVHTCK
Protein: DNA replication complex GINS protein PSF1 (GINS complex subunit 1) (Q9CZ15)
Organism: Mus musculus (Mouse)
Function: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q14691}. Chromosome {ECO:0000250|UniProtKB:Q14691}. Note=Associates with chromatin. {ECO:0000250|UniProtKB:Q14691}.
Interaction partners:
- DNA replication complex GINS protein PSF2
- Cell division control protein 45 homolog
- DNA replication complex GINS protein SLD5
- DNA replication complex GINS protein PSF3
- DNA replication licensing factor MCM3
- DNA replication licensing factor MCM6
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM5
- DNA replication licensing factor MCM2
- DNA replication licensing factor MCM7
Sequence:
MFCEKAMELVRELHRAPEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSAGRGDLIPTVKFRHCALLRNRRCTIAYLYDRLLRIRALRWEYGSVLPNSLRFHMSAEETEWFNHYKKSLATYMRSLGGDEGLDITQDVKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHVLS
Protein: Probable glutamate--tRNA ligase, cytoplasmic (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) (O13775)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- tRNA-aminoacylation cofactor arc1
- Probable methionine--tRNA ligase, cytoplasmic
- Putative leucine--tRNA ligase, cytoplasmic
- Putative proline--tRNA ligase C19C7.06
- Isoleucine--tRNA ligase, cytoplasmic
- Probable arginine--tRNA ligase, cytoplasmic
- Putative leucine--tRNA ligase, mitochondrial
- Isoleucine--tRNA ligase, mitochondrial
- Probable glutamine--tRNA ligase
- Elongation factor 1-gamma
Sequence:
MSVSVALKAKPIAYGAVACANYVNLSGAGSISVKYEDVALLDKQNKESNVSIQLNGSDSPVFGSKLALQTFSQVYPKLFIGENDRSLVESWVETASALAGNHNFLELSSLLAQLDDHLIMRSLFVGYSLTSADFSIWGALKSNNMAAGAVRTGQYFNLARWYKFMDSQNAVSVTMEEFTKAVNISKKQKSSGPNYEIGLPDAIDGKVVTRFPPEPSGYLHIGHAKAALLNQYFANKYHGKLIVRFDDTNPSKENSEFQDAILEDVALLGIKPDVVTYTSDYLDTIHQYCVDMIKSGQAYADDTDVETMRHERTEGIPSKHRDRPIEESLEILSEMDKGSDVGLKNCIRAKISYENPNKAMRDPVIYRCNLLPHHRTGTKYRAYPTYDFACPIVDSLEGVTHALRTTEYRDRNPLYQWMIKAMNLRKIHVWEFSRMNFVRTLLSKRKLTEIVDHGLVWGWDDPRFPTVRGVRRRGMTIEALQQYIVSQGPSKNILTLDWTSFWATNKKIIDPVAPRHTAVESGDVVKATIVNGPAAPYAEDRPRHKKNPELGNKKSIFANEILIEQADAQSFKQDEEVTLMDWGNAYVREINRDASGKVTSLKLELHLDGDFKKTEKKVTWLADTEDKTPVDLVDFDYLITKDKLEEGENYKDFLTPQTEFHSPVFADVGIKNLKKGDIIQVERKGYYIVDVPFDGTQAVLFNIPDGKTVNRYGVKN
Protein: GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Q7M8G0)
Organism: Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / CCUG 13145 / JCM 31913 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
Interaction partners:
- Isoprenyl transferase
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
- POLYPRENYL SYNTHETASE
- 1-deoxy-D-xylulose-5-phosphate synthase
- Uncharacterized protein
- THIF-type NAD/FAD binding fold domain-containing protein
- 5'-nucleotidase SurE
- Nucleoid-associated protein WS1681
- Aspartate 1-decarboxylase
Sequence:
MNLESVMEGFERFLEEEAPLFEGFHPHYNEYLWEMVRNGGKRFRPRLLLGVVSALAPLLVKSAYAPALALEILHTYSLIHDDLPAMDNAATRRGHPTLHVKYDEASAVLAGDALNTHAFYLLAQAPLGSDTKVALVRELASAGGAGGMVLGQALDCYFEHQKLEIEKLRFIHLHKTGRLIAASLKMGAIIAALSKEEQARLEEIGLKLGLLFQVQDDIIDATWSEEEAGKTTQNDGAKNSYVNLLGLEGARMEHARLKEEVRVLLGFFPEALSLTLLEILEKQFKS
Protein: Transcription factor MYB21 (Myb homolog 3) (AtMyb3) (Myb-related protein 21) (AtMYB21) (Q9LK95)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor involved in photomorphogenesis in the light. May act downstream of the light receptor network and directly affects transcription of light-induced genes. In darkness, its probable degradation prevent the activation of light-induced genes. Required to activate expression of PAL. Acts redundantly with MYB24 and MYB57 to control stamen filament elongation in the late developed flowers. Contributes with MYB24 to induction of MYB108 by jasmonate. Repressed at the transcript levels by DELLA proteins.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor MYC2
- Transcription factor MYC4
- Transcription factor MYC3
- Protein TIFY 3A
- Protein TIFY 5A
- Protein TIFY 10A
- Transcription factor GLABRA 3
- Protein TRANSPARENT TESTA GLABRA 1
- Transcription factor TT8
- Transcription factor EGL1
Sequence:
MEKRGGGSSGGSGSSAEAEVRKGPWTMEEDLILINYIANHGDGVWNSLAKSAGLKRTGKSCRLRWLNYLRPDVRRGNITPEEQLIIMELHAKWGNRWSKIAKHLPGRTDNEIKNFWRTRIQKYIKQSDVTTTSSVGSHHSSEINDQAASTSSHNVFCTQDQAMETYSPTPTSYQHTNMEFNYGNYSAAAVTATVDYPVPMTVDDQTGENYWGMDDIWSSMHLLNGN
Protein: ER membrane protein complex subunit 4 (Q584P6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
- ER membrane protein complex subunit 1
- ER membrane protein complex subunit 3
- ER membrane protein complex subunit 2
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 7 beta-sandwich domain-containing protein
- Vacuolar protein sorting-associated protein 28 homolog
- MPN domain-containing protein
Sequence:
MRKQLNMQEEGDASTARTHRRLNDLRMQPLSSLPMTIFMMWMVGNDVSIFSIVFVGMAVTNPLQSMLGAAKVFEEFNEEAEKDPHVRSAVGHSKLIYIACCFAALAVALIKLNWMGLMPVNAMDWLDSTPPQYKEQSMGTFFS
Protein: Protein S100-G (Calbindin-D9k) (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (P97816)
Organism: Mus musculus (Mouse)
Interaction partners:
- Calbindin
- Transient receptor potential cation channel subfamily V member 6
- Transient receptor potential cation channel subfamily V member 5
- Plasma membrane calcium-transporting ATPase 1
- Parvalbumin alpha
- 45 kDa calcium-binding protein
- S100 calcium binding protein A2
- Calcium-binding protein 4
- Calretinin
Sequence:
MCAEKSPAEMKSIFQKYAAKEGDPDQLSKEELKLLIQSEFPSLLKASSTLDNLFKELDKNGDGEVSYEEFEAFFKKLSQ