wanglab/gogpt-training-data huggingface dataset:
Protein: Aquaporin-9 (Q7JMQ6)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MILDKLRAKFHIRKELLRAVLAEFTGTYLLCLIGLSVVAQKVLPRPEVNEFIGVNVGFGIAIVFGVAVSAKLSGGHINPAVSFAFLSVGQITIVQFIAYFVAQFFGAFFGAATVYAVYNDAINVFDGGVRTVGGPKDTAGIFASYPAPHLGLVNGFVDQFVATAVFVFLIAHIVDKRNSYPTWLQPILVGTGFVAIGAAFGYNCGYPVNPARDFAPRLFTSIFYGGAVFTKWFWVPIVGPFVGAVVGIWLYYFLIGFHTPQDAEEKYVVLTGNQELKPLTAKESA
Protein: Ubiquitin carboxyl-terminal hydrolase, putative (EC 3.1.2.15) (Q381H6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Small ribosomal subunit protein uS5
- Ribosomal protein L11, putative
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein bL21m
- Polyubiquitin, putative
- KOW domain-containing protein
- 40S ribosomal protein S18, putative
Sequence:
MRSGGFASEAPSGDTTTADEGSDVAPHASGCVQYDMDGMPAFKGSVCPKSPIQDPLVNPLDGYVEALVKRLGEALDPLGLAGALLRSSHVVTTFKEGVAVFDLPWVALLRDASEKAFSSVDPALEELVSRDTFPAADNGASLNNARGNLVCGMTELAGVLRRCYSALGAAPLCSFDDVHERLLSISRRFVGDIGSSRGPFSTAQVPLSMEELKALLLQDVNRWGLSTFPYLVFAVSSRHPLQLVWNDATVDKAELAFHVYYMVARINRWEEETGSGRGILFPVEWMDELLRWLTDRDEVPLLPLRCPSQSLTPVSQMDYSPVPCAPGPFDISRVLRVTAEDPSKHMVQYDDGGVDVIPEDLFDYLWSLFGGGAKYIVMGKFRNKSKIMELLKPKRVSIAVTFEGSDREGQLRVDSLLLDDVLPRASLSEVSRRAIGELLDKHQYGWENGMELFGLTRPDNVIEMCVTHVHGKELQASRLVEVVDGKTVEDLLGDFRSSTEVVTDHCGPVLRVSLLVRHPAGLTSPAGPGFCGLTNVGNTCYMNSALQCLLSLGAVCRLLFSLRLSEYANLSITREFVNLLRDMLAGRRVAKTLPLKTAIGSVERRFNTYEQQDAVEFIEVLLDRIHEEMNHVYGKRYRERLDTDKDIPKSKLANCFWEDAKANNQSFVPQLFSHQSVHFFVCCNCKGTSTVFDNGSTLVATIAPPTRRVFDVDVLLPGELVRRVQVKVACGSDDRVRASDIEKEIWERLHSTNTDFFSSMATSVGCPEAQAPLKGKGQDNKQSLGDYRAVLCADSHTCFSDGGHVLHAAVLWRGAGLGAGEKRVLPTGPSLANRNSTEEFAEAQPMCNEFQQQREMKDQCVYIWYFLQPQGSSSPRDALLCHVECSSVDALGDRKSSLAYIIERSVNLGDHFLSWKLGCVDQCTSLEQDGGENKHLQRGPKKNLRVWFCSTMGDNGYYLNLEDTGDGRDWIDSGDLPLTLSMDSRVVIQYDDQMMQLSDAIRVTNFHSVGSSPFPGEPTFYSCNGTNKEAVDVHECLKSTFSSDILTGENSLNCSKCGGFCDGRVERRLFRLPPCLIISLKRFKLDIRGVTKDTAFVRFSEELDMKQFMDEESPEKHTKYKLVGVVFHRGGLSYGHYTAARFSKATKQWFCCDDSSVMVRDKGPWAWPAAGDAYILCYEQLVEG
Protein: Deneddylase 1, isoform C (E1JH43)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ubiquitin-like protein NEDD8
- Nedd8-activating enzyme E1 catalytic subunit
- Nedd8-activating enzyme E1 regulatory subunit
- Nedd8-conjugating enzyme UbcE2M
- DCN1-like protein 1
- Aconitate hydratase, mitochondrial
- Aconitate hydratase, mitochondrial
- Cytoplasmic aconitate hydratase
- Cytoplasmic aconitate hydratase
Sequence:
MLPHDRKILRQHTRQNQNTNRRRPRFTNNSFHTKMGSNSKADPISLTFHDSCLRMSDVQLLHGPHWLNDQILSFYYEYLAHMKYKTNADLHFIAPEITQCMKYMGDQELKQLLDQSNTTGKPFIFFALNDNETTDAGGSHWSLLVFSRPEKTFYHFDSYGNNNTGNSLELMNKIKDLLGVRMAKFRPMRCLQQANGYDCGIHVICMTDHIADYLNRYEVIDGLPSLHIDTVKAKRTELLKLILSLGGKG
Protein: Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18) (Q6NYC8)
Organism: Homo sapiens (Human)
Function: May target protein phosphatase 1 to F-actin cytoskeleton.
Subcellular location: [Isoform 1]: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24434620}.; SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17374523}.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Sequence:
MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGLRTKALIVDESCRR
Protein: Aldehyde reductase 1 (ALR 1) (EC 1.1.1.2) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase I) (P27800)
Organism: Sporidiobolus salmonicolor (Yeast-like fungus) (Sporobolomyces salmonicolor)
Function: Catalyzes the asymmetric reduction of aliphatic and aromatic aldehydes and ketones to an R-enantiomer. Reduces ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate.
Interaction partners:
Sequence:
MVGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIKEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGNNTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSVIPKSVTPSRIGENFKQVSLSQEDVDAVSKLGEGSGRRRYNIPCTYSPKWDINVFGEEDEKSCKNAVKIK
Protein: 4-sulfomuconolactone hydrolase (EC 3.1.1.92) (4-carboxymethylen-4-sulfo-but-2-en-olide hydrolases) (A6XIG7)
Organism: Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Function: Involved in the degradation of 4-sulfocatechol which is a central intermediate in the degradation of substituted sulfonated benzenes. Catalyzes the hydrolytical desulfonation of 4-sulfomuconolactone to yield maleylacetate.
Interaction partners:
Sequence:
MLPADQAGIPPCQGPRARSAPISFAIPKGAWDTHLHVFGPTAVFPYAEKRPYTPPDSPLEDYLALMERLGIERGVCVHPNVHGIDNSVTIDAVERSDRRLLGIIKPHRVMTFTELRDLKTRGVRGVRFAFNPQHGSGALDTELFERMHGWCRELDWCINMHFAPDALEGLCDLIAGAETPIIIDHFGRVETAAGVNQLPFKILRDLATLDHVWIKLTGADRISHSGVPYDDVVPFAHALSEIAPDRLLWGSDWPHSGYFDPKRMPDDGDLLNLVARFAPDVALRHKILVDNPARLFGVI
Protein: GEO13282p1 (RE20019p) (Sosie, isoform B) (Sosie, isoform C) (Q8SXV1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVCQYENSNRTIGVAKFMSSKTKLCLCDNDNGYVEDILHDICSGANLQGLVSFLVSICSLLAPFLVSAHMRKHF
Protein: S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] (P17707)
Organism: Homo sapiens (Human)
Function: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
Interaction partners:
Sequence:
MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
Protein: Respiratory burst oxidase homolog protein A (EC 1.11.1.-) (EC 1.6.3.-) (NADPH oxidase RBOHA) (AtRBOHA) (O81209)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Calcium-dependent NADPH oxidase that generates superoxide.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Calcium-dependent protein kinase 10
- Calcium-dependent protein kinase 1
Sequence:
MMNRSEMQKLGFEHVRYYTESPYNRGESSANVATTSNYYGEDEPYVEITLDIHDDSVSVYGLKSPNHRGAGSNYEDQSLLRQGRSGRSNSVLKRLASSVSTGITRVASSVSSSSARKPPRPQLAKLRRSKSRAELALKGLKFITKTDGVTGWPEVEKRFYVMTMTTNGLLHRSRFGECIGMKSTEFALALFDALARRENVSGDSININELKEFWKQITDQDFDSRLRTFFAMVDKDSDGRLNEAEVREIITLSASANELDNIRRQADEYAALIMEELDPYHYGYIMIENLEILLLQAPMQDVRDGEGKKLSKMLSQNLMVPQSRNLGARFCRGMKYFLFDNWKRVWVMALWIGAMAGLFTWKFMEYRKRSAYEVMGVCVCIAKGAAETLKLNMAMILLPVCRNTITWLRTKTKLSAIVPFDDSLNFHKVIAIGISVGVGIHATSHLACDFPRLIAADEDQYEPMEKYFGPQTKRYLDFVQSVEGVTGIGMVVLMTIAFTLATTWFRRNKLNLPGPLKKITGFNAFWYSHHLFVIVYSLLVVHGFYVYLIIEPWYKKTTWMYLMVPVVLYLCERLIRAFRSSVEAVSVLKVAVLPGNVLSLHLSRPSNFRYKSGQYMYLNCSAVSTLEWHPFSITSAPGDDYLSVHIRVLGDWTKQLRSLFSEVCKPRPPDEHRLNRADSKHWDYIPDFPRILIDGPYGAPAQDYKKFEVVLLVGLGIGATPMISIVSDIINNLKGVEEGSNRRQSPIHNMVTPPVSPSRKSETFRTKRAYFYWVTREQGSFDWFKNVMDEVTETDRKNVIELHNYCTSVYEEGDARSALITMLQSLNHAKHGVDVVSGTRVMSHFARPNWRSVFKRIAVNHPKTRVGVFYCGAAGLVKELRHLSLDFSHKTSTKFIFHKENF
Protein: (-)-limonene synthase, chloroplastic (PsTPS-Lim) (EC 4.2.3.16) (Q20HU7)
Organism: Picea sitchensis (Sitka spruce) (Pinus sitchensis)
Function: Monoterpene synthase (mono-TPS) involved in the biosynthesis of monoterpene natural products. Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) into (-)-limonene. Not able to use geranylgeranyl pyrophosphate (GGPP) and farnesyl pyrophosphate (FPP) as substrates.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MSPVSAIPLAYKLCLPRSLISSSRELNPLHITIPNLGMCRRGKSMAPASMSMILTAAVSDDDRVQRRRGNYHSNLWDDDFIQSLSTPYGEPSYRESAERLKGEIKKMFRSMSKEDEELITPLNDLIQRLWMVDSVERLGIDRHFKNEIKSALDYVYSYWNEKGIGCGRDSVVADLNSTALGFRTLRLHGYNVSSEVLKVFEDQNGQFACSPSKTEGEIRSALNLYRASLIAFPGEKVMEDAEIFSSRYLKEAVQKIPDCSLSQEIAYALEYGWHTNMPRLEARNYMDVFGHPSSPWLKKNKTQYMDGEKLLELAKLEFNIFHSLQQEELQYISRWWKDSGLPKLAFSRHRHVEYYTLGSCIATDPKHRAFRLGFVKTCHLNTVLDDIYDTFGTMDEIELFTEAVRRWDPSETESLPDYMKGVYMVLYEALTEMAQEAEKTQGRDTLNYARKAWEIYLDSYIQEAKWIASGYLPTFQEYFENGKISSAYRAAALTPILTLDVPLPEYILKGIDFPSRFNDLASSFLRLRGDTRCYKADRARGEEASCISCYMKDNPGSTEEDALNHINSMINEIIKELNWELLRPDSNIPMPARKHAFDITRALHHLYKYRDGFSVATKETKSLVSRMVLEPVTL
Protein: Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14) (Q6PVZ1)
Organism: Gallus gallus (Chicken)
Function: The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P02533}. Nucleus {ECO:0000250|UniProtKB:P02533}. Note=Expressed in both as a filamentous pattern. {ECO:0000250|UniProtKB:P02533}.
Interaction partners:
- Type II alpha-keratin IIA
- IF rod domain-containing protein
- Cadherin-1
Sequence:
MSTTVRQFSSSTSLKGLGGGSSRLSCGRAAGYQAPSVHGGSSSYSVSSRIVSGLGAGYGGGYCSSVGGGLGGGFGASYGAGYGAGFGGGFGAGFGGGFGGGDGILPAGEKETMQNLNDRLAAYLDKVRALEEANTDLEVKIREWYKKQGPGPERDYSPYYRTIEELRSKILAATVENANIVLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEISVEMDAAPGIDLTKILAEMREQYESLAEKNRRDAEQWFFSKTEELNREVAVNTEQLQSGKTEITELRRTIQSLEIDLQSQLSTKAALEGTLADTEARYGTQLAQLQALITSVEEQLAELRCDMERQNHEYRVLLDVKCRLEQEIATYRRLLEGEDAHISSQYSSAMSSHSGRDAITTSRQVRTIVEEVQDGKVVSSREQMALTTR
Protein: Solute carrier family 4 member 1 adaptor protein (A0A087WWF4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MADILSQSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPEGQSGDGRTHLNDKYGY
Protein: Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) (Q9JJS6)
Organism: Mus musculus (Mouse)
Function: Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9I993}.
Interaction partners:
- Retinol dehydrogenase 10
- Retinal dehydrogenase 2
- Retinol dehydrogenase 11
- Retinol dehydrogenase 1
- Retinol dehydrogenase 19
- Aldehyde dehydrogenase 1A1
- Retinaldehyde dehydrogenase 3
- Retinol dehydrogenase 16
- Retinol dehydrogenase 12
- Short-chain dehydrogenase/reductase 3
Sequence:
MEIIFGQNKKEQLEPVQAKVTGSIPAWLQGTLLRNGPGMHTVGESKYNHWFDGLALLHSFSIRDGEVFYRSKYLQSDTYIANIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDFTDNCLINIMKCGEDFYATTETNYIRKIDPQTLETLEKVDYRKYVAVNLATSHPHYDEAGNVLNMGTSVVDKGRTKYVIFKIPATVPDSKKKGKSPVKHAEVFCSISSRSLLSPSYYHSFGVTENYVVFLEQPFKLDILKMATAYMRGVSWASCMSFDREDKTYIHIIDQRTRKPVPTKFYTDPMVVFHHVNAYEEDGCVLFDVIAYEDSSLYQLFYLANLNKDFEEKSRLTSVPTLRRFAVPLHVDKDAEVGSNLVKVSSTTATALKEKDGHVYCQPEVLYEGLELPRINYAYNGKPYRYIFAAEVQWSPVPTKILKYDILTKSSLKWSEESCWPAEPLFVPTPGAKDEDDGVILSAIVSTDPQKLPFLLILDAKSFTELARASVDADMHLDLHGLFIPDADWNAVKQTPAETQEVENSDHPTDPTAPELSHSENDFTAGHGGSSL
Protein: Probable peptidyl-prolyl cis-trans isomerase C27F1.06c (PPIase) (EC 5.2.1.8) (Rotamase) (Q10175)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Interaction partners:
- Histone H2A.Z-specific chaperone chz1
- Nucleolar protein 58
- ERAD-associated E3 ubiquitin-protein ligase doa10
- Cell division cycle protein 48
- N-acetyltransferase eso1
- mRNA export factor elf1
- Ribosome production factor 2 homolog
Sequence:
MSKEETLYSVKVDQERVPLFDEDFYKGFRSELSVRFTMAALDPRAKSNDAVTVNVITRLEHPEEDGEESDEELFQEEKFTLCTLKKGSVYQQPIDIIFSPGEEVFFERVGGDIPVYLSGTCIITNIPEEEDSSDLENDFLYGADEFSSDEEEMDDISVTSSEEEEEENGARIEELNSDEEDAEQAEEEILEKPVPKDEVAEKHSKDKLKKEEKEKKTAVDVSDSVNGKKRKTEPAGEGEQTEKKSKSTKTYPKQVLEGNVTVQDKVKGDGPAAKRKKRVSMRYIGRLTNGKVFDKNITGKPFTFNLGLEEVIKGWDVGIVGMQVGGERTIHIPAAMAYGSKRLPGIPANSDLVFDVKLLAVN
Protein: Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (3-demethylubiquinone 3-O-methyltransferase) (EC 2.1.1.-) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114) (Q63159)
Organism: Rattus norvegicus (Rat)
Function: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Subcellular location: Mitochondrion inner membrane {ECO:0000255|HAMAP-Rule:MF_03190}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03190}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03190}.
Interaction partners:
- Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
- NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial
- 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial
- Ubiquinone biosynthesis protein COQ9
- Atypical kinase COQ8A, mitochondrial
- 4-hydroxybenzoate polyprenyltransferase, mitochondrial
- Atypical kinase COQ8B, mitochondrial
- Inter-alpha-trypsin inhibitor heavy chain 5
- All trans-polyprenyl-diphosphate synthase PDSS2
Sequence:
MWRGGRLSSRGVRFLETLGFACPSAVAEPPRVTSWTAFSGNQLTRNLQIKPWEFSGHRTMWLRSYRITFSCLTRLKTYRSSWKKLYSTSQTVDSKEVKTFQALAHSWWDEQGKFAPLHSMNDLRVPFIRDNLLKTSTNHDPGKPLSGMKILDVGCGGGLLTEPLGRLGASVVGIDPVAENIKIAQHHKSFDPVLDKRIQYRVCSLEETLNENAECFDAVVASEVVEHVNNLEMFIQCCYQVLKPGGSLFITTVNKTQLSYVLGIVFSEQIAGIVPKGTHTWEKFVSPEKLESILEPNGLSVETVAGMVYNPFSGYWHWTENTSLNYAAHAVRARAQEHLEPAESA
Protein: Eukaryotic translation initiation factor 3 subunit B (eIF3b) (eIF-3-eta) (eIF3 p110) (Q9M4T6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_03001, ECO:0000256|PIRNR:PIRNR036424}.
Interaction partners:
Sequence:
MAAVVDIDVLTAQLGINWSDVNLDSIQLPPGNDFGIESDDESVYQDDQSEFDTGFGNIIVVDHLPVVPKEKFEKLEGVVKKIYNQLGVIKENGLLMPVDPDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKSHIFAVNMFDDFDRLMNVKEEWEPPQERPYVPGENLQKWLTDDKARDQLVIRFGHDTEVYWNDARQKKPEPVHKRSYWTESYVQWSPIGTYLVTLHKQGAAVWGGADTFTRLMRYQHSMVKLVDFSPGEKYLVTYHSQEPSNPRDASKVEIKVFDVRTGRMMRDFKGSADEFSIGGPGGVAGASWPVFRWACGKDDKYFAKLSKNTISVYETETFSLIDKKSMKVDNVVDICWSPTDSILSLFVPEQGGGNQPAKVALVQIPSKVELRQKNLFSVSDCKMYWQSSGEYLAVKVDRYTKTKKSTYSGFELFRIKERDIPIEVLELDNKNDKIIAFAWEPKGQRFAGIHGDQPNRDVSFYSIKTGTKTLERVSKLATLKAKQAKCPLLVAPQASTSFLAGLKGFNGQLEFFNVDELETMATAEHFMATDIEWDPTGRYVATSVTTVHEMENGFTIWSFNGNMVYRILKDHFFQLAWRPRPASFLTAEKEEEIAKNLRNYSKRYEAEDQDVSLLLSEQDREKRRALNEEWQKWVMQWKSLHEEEKLVRQNLRDGEVSDVEEDEYEAKEVEFEDLIDVTEEIVQELM
Protein: Uncharacterized protein (Q5ANP4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MPYTIGDRRITLDSNLLESDKQLLITHPEIFKYCLNNAVFRSIINLKNLVHLYSDIITIYATFLRKIPHYDDVTLMANKSKLNLLKLEHDFNDIFGQYTTMHEYKKFNSNWEDKTYEGDIVPSALLIIDVATQAFETVYKSLSCIELFFNHYDNLKKLLIPSLVVRTKSILDSFAKIEQFLKLTFPVDKMARGEIVTFDESTFENVRRVEKVTSGIERESIFLETFFLAFDASLTSYTSILLGKGILKRDVPPRDCEIISRRRICYQAAEHVVTIPLSEDSPNKSKSAMEYLGKYIAYIGVSLLILISVVFYRLFKVLFG
Protein: Disintegrin and metalloproteinase domain-containing protein 19 (ADAM 19) (EC 3.4.24.-) (Meltrin-beta) (O35674)
Organism: Mus musculus (Mouse)
Function: Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- SH3 and PX domain-containing protein 2A
Sequence:
MPGRAGVARFCLLALALQLHWPLAACEPGWTTRGSQEGSPPLQHELIIPQWRTSESPGRGKHPLRAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTSTLKSEDHCFYHGTVRDVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDSQHRIYRSEHLTLPPGNCGFEHSGPTSKDWALQFTHQTKKQPRRMKREDLHSMKYVELYLVADYAEFQKNRHDQDATKRKLMEIANYVDKFYRSLNIRIALVGLEVWTHGDKCEVSENPYSTLWSFLSWRRKLLAQKSHDNAQLITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAHCCSASAADGGCIMAAATGHPFPKVFSWCNRKELDRYLQTGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEEECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDLCFERVNAAGDTYGNCGKGLNGQYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLNGRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNKNCHCFPGWSPPFCNTPGDGGSVDSGPLPPKSVGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKPSALPFKLRHQFSCPFRVSQSGGTGHANPTFKLQTPQGKRKVTNTPESLRKPSHPPPRPPPDYLRVESPPAPLPAHLNRAAGSSPEAGARIERKESARRPPPSRPMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTGPRSGGTSLLQPPTSGPQPPRPPAVPVPKLPEYRSQRVGAIISSKI
Protein: LIM domain containing preferred translocation partner in lipoma (Lipoma-preferred partner) (Lpp protein) (Q7ZU85)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MWGGHNDGDQQGHVSARMETSLPMGTTSISISQQQAPKKFAPVVAPKPKFNPYKQPGDATHEGDYPPPPPPVVDPSGLPSPSSFPPPPPMDETSLGFQIKGPEKTLEERRSSLDAEIDSLTSILADLESSSPYKPRTQQNSASPAATGSTAPVTGYRRMVIPTQPPLTATKKSTPKPQAPQNVTPPASSSPRPQYQPAPQPVPASYTTASTPSQPTFNVQVRAAQPAPQQQPVRGPGQVQYMPAQPRAPEFAYGPPQPGFCPAPSGGYQDQHYGGAPGYGGQNTWRAEPSHHPAPTPSQGYQPAPPKKTYITDPPASLAPFAGGSSAPHKGRPEEELDRLTKKMLYDMDNPPSEEYFGRCSSCGENVVGEGTGCTAMDQVFHVDCFICMTCGSKLRGKPFYAVEKKAYCEPCYINTLETCNICYKPIMERILRATGKAYHPQCFTCVVCHRSLDGIPFTVDASNHIHCIEDFHKKFAPRCSVCNEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGCLLSEGDNQGCYPLDGHVLCKNCNTSRIQALTAKATTDL
Protein: Uncharacterized protein (Q385J3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVRSQSRPFSSGKRGVGQQQQQQQQKQQQQQKQQVQPQKQQQQQHQEQQQQQRQQQPTLTEQKDKVVALSSSSSDVSVSAVTEYKTGEETASSPQPSPGIVNHAEGPQNWREQLFLRNFPTGETAQQHAKGHSPKRRKSANSFSTIGRRGSFVLSHTVTPRKKPLESQEEQLETYRSLQDRQFVSVHEELQHLRVMYTNLQKVVSRKNEEIEKLHQEVLTKTKEIERLTGLVDKLSKRRGNSTGSALDEGRAASARGSRPSFSPSLALYAKGASEDKLSNKVNGAGGAPAKMLLELRQNVASRDTIIDNLRMELHSAQHEKKESESKANKLGTELEDAKAQVTKLRSDLTTRDAVIEDMQRRLVSLPETTVGSSSQGLYRTPNSSNNSGPPTKQPMLHELGGNCLASNGALEHMRHDSQQLGGAGTLPYKSALCPGTQHQDLESAFRLELEHLRRCLEREKDTNSELEKHWRRRQEVEKRMAEVELNTARAEAEAFRRELTRLQQQQAMSNFAENQLQTARSENDVLQQRVQELREENAAQASREMELRNNVRLLRETCERHEEEVETLHRRMKVMKDNEIRLQEDIDILEEKLSRAERMRAAEQNGNNSLSCDIGSYVSLMSLNEKLQRRTEELEEQIRKMEECHAATPHDDFKKECGQEHVFTTPDVEAGAIGGISPASLDSQGGVIEFLTPPVSTGGGDAAACSTHEAGDSMICNGQAVGGSRKSVNNLPLEVKETTDVSTVVQQLQDELQGVRDRLRVTESELAMLREKQALSEERVRETVKRKVTSLRAAREEAARCWEMLRQQEVLVKRLQKQCEYQREIIESRDPPLLGPMRLSTQASAPTVCAPTTCIETKDGNTANETSREDKLIEEALRWESMRLDEEMKLLRQKLRRTVEERDHWKNLATGNSGEII
Protein: Histone H2B 1.1 (H2B1.1) (P02281)
Organism: Xenopus laevis (African clawed frog)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
Sequence:
MPEPAKSAPAPKKGSKKAVTKTQKKDGKKRRKSRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Protein: choline-phosphate cytidylyltransferase (EC 2.7.7.15) (Q7K4C7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RE24176p
- choline-phosphate cytidylyltransferase
- diacylglycerol cholinephosphotransferase
- Glyoxylate reductase/hydroxypyruvate reductase
- Phosphatidylserine decarboxylase proenzyme, mitochondrial
- GH11618p
- FI05338p
Sequence:
MATSSILAKSTINSTSPPATPSSSASPGSTLTTRKRTYEIAIAMPSSTASSSATKVSEVQDQRTNSPGKSKSRPGQLESVLVVGEGASEPTTSATTLRDSTRTISQSDADDGGEAAAAEDLLPPQSDYLNGVKRKYVPQQQASPNHRVVPASTSQQFFSGASDFATICKPAPYSHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPNVYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARIVKDYDLYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKSRGKRELSKVKVDIITKWEEKSREFIDTFLLLFGRENLNHLWNESKGKLLQALSPPGSPSGSVNGDDTEGGEDYSETIDEYLEMAEKLSGGSGSGSSGSLNGKQRPKQKRSSLARRSYQSLQSQSPDLEADGDEDADADAEYERRSN
Protein: Lipopolysaccharide induced TNF factor (I3L329)
Organism: Homo sapiens (Human)
Subcellular location: Endosome membrane {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004125}. Late endosome membrane {ECO:0000256|ARBA:ARBA00004414}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004630}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004630}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004630}.
Interaction partners:
Sequence:
MSVPGPYQAATGPSSAPSAPPSYEETVAVNSYYPTPPAPMPGPTTGLVTGPDGKGMNPPSYYTQPAPIPNNNPITVQTVYVQHPITFLDRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLG
Protein: ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme) (Q91V92)
Organism: Mus musculus (Mouse)
Function: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P53396}.
Interaction partners:
- Fatty acid synthase
- Citrate synthase, mitochondrial
- Citrate synthase
- Acetyl-CoA carboxylase 1
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Pyruvate carboxylase, mitochondrial
- Malate dehydrogenase, mitochondrial
- Aconitate hydratase, mitochondrial
- Cytoplasmic aconitate hydratase
- Succinate--CoA ligase subunit alpha, mitochondrial
Sequence:
MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWAHLLQDHPWLLSQSLVVKPDQLIKRRGKLGLVGVNLSLDGVKSWLKPRLGHEATVGKAKGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNTEDIKRHLLVHAPEDKKEVLASFISGLFNFYEDLYFTYLEINPLVVTKDGVYILDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTREKHPEGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQGKSATLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMKKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPVVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVAKGAIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQRRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDFVKQHFPATPLLDYALEVEKITTSKKPNLILNVDGFIGVAFVDMLRNCGSFTREEADEYVDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM