wanglab/gogpt-training-data huggingface dataset:
Protein: Aspergillus nidulans myosin V homolog (Eurofung) (Q5AS68)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Ras GTPase similar to RAB11B
- Calmodulin
- Kinesin-like protein
- Calmodulin
- Actin, gamma
- Rab GTPase SrgA
- Myosin II homolog
- Actin-related protein
- GTP-binding protein ypt1
- Exocyst complex component Sec8
Sequence:
MAHNYEVGTRAWQPDATEGWVASEVKEKLVDGDKVRLVFVLENGEPKEIETTQAELQVDNNPNLPPLMNPAMLEASEDLTNLSHLNEPAVLQAIKLRYAQKEIYTYSGIVLIATNPFARVDSLYVPQMVQVYAGKHRASQAPHLFAIAEEAFGDMLRDGKNQTIVVSGESGAGKTVSAKYIMRYFATRESSDQPGKYTTSRADAISETEEQILATNPVMEAFGNAKTTRNDNSSRFGKYIEIMFDDKTNIVGAKIRTYLLERSRLVFQPLKERNYHIFYQLVAGASDTEKQELGLTSVEDFDYLNQGGTPIIDGVDDKTEFIATKKSLGTIGVPETIQSEIFRVLAALLHLGNVKITATRTDSTLSPSEPSLSRACEILGIDANEFAKWIVKKQLITRGEKITSNLTQQQAIVVRDSVAKFIYSSLFDWLVDKINRGLATDEVLNKFKSFIGVLDIYGFEHFAKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVREQIDWTFIDFSDNQPCIDLIEAKLGILSLLDEESRLPMGSDEQFVTKLHHNFAADKQKFYKKPRFGKSAFTICHYAVDVTYESDGFIEKNRDTVPDEHMEILRNSSNNFVKEILDTAASVREKDSAAVSSKPVTAPGRKIGVAINRKPTLGGIFKSSLIELMSTINSTDVHYIRCIKPNEAKEAWVFEGPMVLNQLRACGVLETVRISTAGYPTRWTYEEFAIRYYMLCHSSQWTSEIKDMCHAILRKALGDATQQKHDKYQLGLSKIFFRAGMLAFLENLRTSRLNECAIMIQKNLRCKYYRRRYLEARLSVLATQSLVRGFLARQRAAEIRRIKAATTIQRVWRGQKERKRYNQIRDNVILLQSLSKGFLCRRNILNSIHGNAAKTIQRAFRSWRQLRAWRQYRRQVIIVQNLWRGKKARREYKVLREEARDLKQISYKLENKVVELTQYLESLKRENKSLNSQLENYETQLKSWRSRHNALENRSRELQAEANQAGITAARLTALEEEMSILQQNHADGQATIKRLQEEERISRDSIRSANQELEKLKQLNAEAESERTSLRQQVIDLEEQLEVAKRTLPLQALNGDQQNGGSVPPPANGLINLVSSKKTKPKRRSAGAERIDTDRFSGAYNPRPVSMAIPSALGRQNYSVAALSSGLDSVEAELETLLSEEDELNEEVAIGLIRNLKIPAPNSTPPPTEKEVLFPAYLINLVTSEMWNNGFVKESERFLANVMQSIQQEVMQHDGDDTISPGAFWLSNVHEMLSFVFLAEDWYEAQKTDNYEYDRLLEIVKHDLESLEFNIYHTWMKLLKKKLYKMIVPAIIESQSLPGFVTNETNRFLGKLLPSNNNPAYSMDNLLSLLNNAYKAMKAFYLEDSIITQTVTELLRLVGVTAFNDLLMRRNFLSWKRGLQINYNITRIEEWCKSHDMPEGTLQLEHLMQATKLLQLKKATLNDIEIIQDICWMLSPNQIQKLLNQYLVADYEQPINGEIMKAVASRVTEKSDVLLLTPVDMEDSGPYEIAEPRVITALETYTPSWLQTPRLKRLAEIVSAQAMAQQDKPENTENGVME
Protein: Tumor necrosis factor receptor superfamily member 16 (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (CD antigen CD271) (Q9Z0W1)
Organism: Mus musculus (Mouse)
Function: Low affinity neurotrophin receptor which can bind to mature NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF (proNGF), BDNF (proBDNF) and NTF3 (proNT3) with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. The heterodimeric receptor formed with SORCS2 plays a role in proBDNF-dependent synaptic plasticity, in hippocampal long term depression (LTD) and long term potentiation (LTP). Plays a role in the inactivation of RHOA (By similarity). Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Necessary for the circadian oscillation of the clock genes BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11559852, ECO:0000269|PubMed:1317267, ECO:0000269|PubMed:22155786, ECO:0000269|PubMed:9857182}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000250|UniProtKB:P08138}. Perikaryon {ECO:0000269|PubMed:22155786}. Cell projection, growth cone {ECO:0000269|PubMed:22155786}. Cell projection, dendritic spine {ECO:0000269|PubMed:29909994}.
Interaction partners:
- Neurotrophic factor BDNF precursor form
- High affinity nerve growth factor receptor
- Neurotrophin-4
- Neurotrophin-3
- Sortilin
- Beta-nerve growth factor
- Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
- Melanoma-associated antigen D1
- Neurotrophin receptor-interacting factor 1
- Protein BEX3
Sequence:
MRRAGAACSAMDRLRLLLLLLLLLGVSFGGAKETCSTGMYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPCTECLGLQSMSAPCVEADDAVCRCSYGYYQDEETGRCEACSVCGVGSGLVFSCQDKQNTVCEECPEGTYSDEANHVDPCLPCTVCEDTERQLRECTPWADAECEEIPGRWITRSTPPEGSDVTTPSTQEPEAPPERDLIASTVADTVTTVMGSSQPVVTRGTADNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEKLHSDSGISVDSQSLHDQQTHTQTASGQALKGDGNLYSSLPLTKREEVEKLLNGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWGAQDSATLDALLAALRRIQRADIVESLCSESTATSPV
Protein: Kinesin K39, putative (Q57UD0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MISNIRRAGEQNSGKNNSTMTDESRNSLTTTEMTTNACDESIKVAVRVRPQNTSEMSGTHKLALRANTSYSTITLIDHHSKSSQCPRAQTFQFDNIFCSCGCTDEGGLPPAGQLEVYEAIGRPLVMHAFNGYNSCLFAYGQTGSGKTYTMMGGDPGSVSGVDAGVIPRLCLEIFEKRARIEGKGHSRWKVTVGYVEVYNERVSDLLARRRKGSREDVFVDVREHPTMGVFIEGQRLQEVSSVEEVVELIELGNRVRHTASTKMNDRSSRSHAIFMLILHEERSTQTASGQVITTAGMSSRMNLVDLAGSERVAQSEVVGQQFNEARYINLSLTTLGRVIDMLADMAKNKSSQWSTPPYRESKLTYILKDSLGGNSKTFMIATVSPSALNYEETLSTLRYASRARDIVNMTRVNEDPRARRIRELEEQMEQMRQDIKGKDPTYVRELEEKLVLLEAEAQKRAADLHALEKEREKNIIREKMLYATEVEREELLIKATELERQVEESKRRAEYHEEMSQRLKDEYAQREQELLEKVRQHRAEIEGIRERKDAEMLSSQQQLSRVMSELEQERHSREEALHILRERQEQLSAALCNSQQSSEKHTELQQQNEELSHRMQKLLEECEAQQRILSDLEVFRLERNELEEIAQFLDLKLEETEHRHIKTINHLLTTIGMHNLWQAELLTAVGTEVETQLTKCNQHHFDQRAAMEKNHKLFQMEQHQMTKKLEQKILMLEKEIEEAKKQLDTTKQSEAAITNKARQAEDARAAVERNLETVEAERDELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDVFERECAVLNIRLSYLRRKLLSGFVVGEEPYKLTRKIINIGK
Protein: SUN domain-containing protein 2 (Q54MI3)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein TAPT1 homolog
Sequence:
MIINKKYILFILLLLFITSCTIVFSQQQQQQTEQSEQTEQAINNDVNNSINDIFENDSSKQLRQPQQQHTIVDDGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNPIDNKDILGLKKLALLKQFEEQKSKSENDINNDIVILNLENDNPNQIIETTTTTLNNSNDNKNNIIDDNQDEKLNENIKEDKNEIKNEIKNENQEKDKGIIDVEKDENQPNIEEKGKEKQNLLEKGIENENQNENQIQIEKEKEIEIEIEKEKEKENKELIEESKTEKDNQQKENKENTNEINVTVVEEPEQPQPQQQNQQEQQEQQQQEHKEEQQQQEQQQQEQQTQQEQQTHQQQQEHQETQKNSSEETKTQSPIQVNTTDVNNEIELKNEGDNNSQLNDSSIPITSPLTNDNDTLKTTKEDSNNNNKNEVINNQTPLIDEKNHQHNYEGNNRNGDDVSIISNIPKTNKAPETQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVVLTPNDLPDKFNYASSECGANVLQTNKEAWEVSSILASSRDRYLLNECNKSQWFVVELCEEIGVQIIELANFEFFSSMFKDFIVLGSNRYPAQSWHYLGQFTAENSRKQQYFVLKEKAWYKYLKVKILSHYGDQLYCPISSFKVYGSTMVDDLKNQVDINISELEKFQRDLSSIPYPMEIGSDTSYSTTTSTTSSSSTSSSYPSSKTKSSNSEYPSWERIQSFSEKLRKNVEQQLIQPPSVLNTNDNNNNNNNNNNNNNNNNNNNNNNNNNEEQFIYYETNGNGGPPSTSTSTSSSSSQNHQARTPQSVFKTLADKIKAIEFNQSIGNKFMEKLERYYSEEIKNLKFDVSEFLNDIIKLGNSLDEKLKDHRKYDDNKFKETSKEIKILKEKIEKLEEQKSADRNFYLVVTLVSLLIGLLLKPLFTSSSSSSNKSYPNSMPNSPTYLNSGSNNYNNNGIINSSGGSGGGGGNLQNSSFIGINGQLNFSDDNISAFLNSSCSNFGLNNNNNNNNGINNNNNNSNSNSNNNSINNGSININSNNSLQQRIHHNKYIHQRRNSSPLVGVQLESFFSPNAIPPTIPIVPQDDNNINYNYNNNNNTNNINNNYNYNNNNNNNNNNNNNNNNNNNNNSDNYNNNNNSNNNVNSPSSPTPSSIILSPKFITSIPKNINYYNNGGSGSHLKNRFSRQASESVLSQNHYQINHQNHSLNGVTTNINNNNSNSNGNSNGNSNNMTNGLPPVSMPSSSSHDNLLLHRGNNQSKKYKRRSHL
Protein: Nuclear mitotic apparatus protein 1 (A0A8I6AMK5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MTLHATRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQKVMEGSEMELAKMVMLFLYHSTMSSRNPRDWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFLEKVPSTYPSTLSEELSPPSHQAKRKIRFLEIQRIASSSSENNFLSGSPSSPVGDILQTPQFQMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLETSLDSLGDAFPDSGRKTRSARRRTTQIINITMTKKLELEEPDSANSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRPTTRSSARRSQTRTSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNRVCPPHLKTCYPLESRPALSLATITDEEMKTGDPRETLRRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATSCFPRPMTPRDRHEGRKQNSTADAQKKAAPVLKQSDRRQSMAFSILNTPKKLGNSLLRRGTSKKTPAKVSPNPRSGTRRSPRIATTTAGAATAATTPRAKGKAKH
Protein: Aquaporin 1a (Aquaporin-1a.1) (Zgc:85890) (Q6NZ72)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Aquaporin-10b
- Aquaporin
- Anion exchange protein
- Uncharacterized protein.
- Aquaporin-3
- Aquaporin 7
- Aquaporin 9b
Sequence:
MNELKSKAFWRAVLAELLGMTLFIFLSITAAVGNTNTQNPDQEIKVALAFGLSIATLAQSLGHISGAHLNPAVTLGLLASCQISLLRAVMYILAQMIGATVASAIVLGVSKGDALGLNQIHTDISAGQGVGIELLATFQLVLCVLATTDKRRRDVSGSAPLAIGLSVCLGHLTAISFTGCGINPARTFGPAMIRLDFANHWVYWVGPMCGGVAAALIYDFLLYPKMDDFPERVRVLVSGPATDYEVNGTDDPPAVEMSSK
Protein: B3 domain-containing protein At1g16640 (Q9FX77)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326}.
Interaction partners:
- Putative B3 domain-containing protein REM4
- AP2/ERF and B3 domain-containing transcription factor RAV1
- B3 domain-containing protein REM3
- B3 domain-containing protein REM14
- B3 domain-containing protein REM5
- Major facilitator superfamily protein
- B3 domain-containing protein At1g20600
- Putative B3 domain-containing protein At4g03170
- B3 domain-containing transcription factor VRN1
- Serine/threonine-protein kinase RHS3
Sequence:
MADTGEVQFMKPFISEKSSKSLEIPLGFNEYFPAPFPITVDLLDYSGRSWTVRMKKRGEKVFLTVGWENFVKDNNLEDGKYLQFIYDRDRTFYVIIYGHNMCSEYRDFPQVAVEVDDYENGEEEEDGDDQDKHQ
Protein: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta) (Q9NRZ5)
Organism: Homo sapiens (Human)
Function: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8K4X7}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
- 1-acyl-sn-glycerol-3-phosphate acyltransferase beta
- Membrane-bound glycerophospholipid O-acyltransferase 2
- Membrane-bound glycerophospholipid O-acyltransferase 1
- 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
- Phosphatidate cytidylyltransferase 1
- Phosphatidate cytidylyltransferase 2
- 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
- Phospholipid phosphatase 4
- Phospholipid phosphatase 5
Sequence:
MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSDSKQKLND
Protein: Sorbitol dehydrogenase 2 (SDH 2) (EC 1.1.1.-) (Polyol dehydrogenase) (Xylitol dehydrogenase) (EC 1.1.1.9) (Q07786)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) and xylitol as substrates, leading to the C2-oxidized product D-fructose and D-xylulose, respectively.
Interaction partners:
- NADPH-dependent aldose reductase GRE3
- Xylulose kinase
- Sorbitol dehydrogenase 1
- Hexokinase-2
- Glucokinase-1
- Hexokinase-1
- N-acetylglucosamine kinase
- Putative glucokinase-2
- Mannitol dehydrogenase DSF1
- Transaldolase
Sequence:
MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYDYNIAHGGEVVKTIIFGPE
Protein: Protein GRE1 (Genes de respuesta a estres protein 1) (Hydrophilin) (Q08969)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Protein SIP18
- 12 kDa heat shock protein
- 6-phosphogluconate dehydrogenase, decarboxylating 2
- Transketolase 2
- Sporulation-specific wall maturation protein
- Stationary phase protein 4
- Transaldolase NQM1
- Aldehyde dehydrogenase [NAD
- Catalase T
- Protease A inhibitor 3
Sequence:
MSNLLNKFADKLHGNDHDERYEDDNDDQTRQQRHEKHQQREFRNQGSKADPYGEENQGNFPQRQQPQSNLGGNTQFGGNDFQQQTTDYTAGTGGGTYTQTYRETNTQGQLDDDEDDDFLTSGQQQKQGRTRGAQSNRYQSSNIGSGRRDLSGSGNDEYDDDSGNQGVW
Protein: RIB43A-like with coiled-coils protein 2 (Q32LJ7)
Organism: Bos taurus (Bovine)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37327785}.
Interaction partners:
- Tektin-2
- Tektin-3
- Parkin coregulated gene protein
- EF-hand domain-containing protein 1
- Outer dynein arm-docking complex subunit 2
- Meiosis-specific nuclear structural protein 1
- Outer dynein arm-docking complex subunit 1
- Tektin-4
- EF-hand domain-containing family member C2
- Tektin-1
Sequence:
MEVAQPKDLKEDFVLAKRRHAELVRQKRIFNARNRIIGGDTTAWDAQVCDQNIKAATEKARDEAFAAEMRQNDKIACLSENRERRDRKNLCKAINDFQQSFQRPETRREFDLSDPLALKKDRPARQSDYDARNTISGMQKFMGEDLNFHLRKKFQEEQNREWSLQQQKEQMIGRENQKCAEDLYLKTRLQFDETAKHLQNLETATRKAVCATVKEFNKNQALESAEKKIQERKQEQEDNLAEISNMLRGDLLSENPQQAASSFGPHRVVPDRWKGMSQEQLEEIRLVQRQQVQEKLRLQEEERQRDMDWDRRRIQKARATLLFEQQQQRLQRGLRRALDCSNLSLAREQLLQKKHMKELCTNHATEDYFTQFNTGSR
Protein: Double C2-like domain-containing protein alpha (Doc2-alpha) (Q7TNF0)
Organism: Mus musculus (Mouse)
Function: Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Synapse, synaptosome {ECO:0000250}. Lysosome {ECO:0000250}.
Interaction partners:
- Protein unc-13 homolog B
- Protein unc-13 homolog A
- Synaptosomal-associated protein 25
- Rab effector Noc2
- Myeloid leukemia factor 2
Sequence:
MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRRGPGPEGGGGGGGTGCGEAPAHLAPLALAPPAALLGATTPDDGAEVDSYDSDDTTALGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEAQKHWNDCLHQPDTALERWHTLTSELPPAAGAYPLA
Protein: Cell cycle checkpoint control protein (O96533)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Rad17
- DNA repair protein Rad1
- Checkpoint protein Hus1-like
- Mutagen-sensitive 101
- Replication factor C subunit 2
- Replication factor C subunit 2
- Replication factor C subunit 3
- Replication protein A 70 kDa DNA-binding subunit
- Serine/threonine-protein kinase ATM
- Activator 1 subunit 5
Sequence:
MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPPHSDFYCKISMKGCLAVFRNMNEVEYCELNLLDNQTNLQVNLRCKLETTKEATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAECLNASLTLEFDEAGMPFLLKIKKHGEIECLLIMSTLSPDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKRKGSSSEPAAVQPKRRVEETQLESSLDNPLFQFRDSEAPSVQHPRILAEVDTVVLIEDEAEQEALMLAAADAALEASMAPAPEPPNSTEVCFINTDDSQQPKPAKSSSDEDETIPQSPERPNKVLGVLLGLLQGCVSRLKTMLRLDEHLISGYELL
Protein: Protein transport protein BOS1 (Bet one suppressor 1) (P25385)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Interaction partners:
- Golgi SNAP receptor complex member 1
- Protein transport protein SFT1
- Protein transport protein SEC22
- Integral membrane protein SED5
- Synaptobrevin homolog YKT6
- Protein transport protein BET1
- Protein SLY1
- Intracellular protein transport protein USO1
- Protein transport protein SEC9
- Syntaxin UFE1
Sequence:
MNALYNHAVKQKNQLQQELARFEKNSVTAPISLQGSISATLVSLEKTVKQYAEHLNRYKEDTNAEEIDPKFANRLATLTQDLHDFTAKFKDLKQSYNENNSRTQLFGSGASHVMDSDNPFSTSETIMNKRNVGGASANGKEGSSNGGGLPLYQGLQKEQSVFERGNAQLDYILEMGQQSFENIVEQNKILSKVQDRMSNGLRTLGVSEQTITSINKRVFKDKLVFWIALILLIIGIYYVLKWLR
Protein: Small ribosomal subunit protein eS10B (40S ribosomal protein S10-B) (O13614)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS13B
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein eS24B
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS9A
- Small ribosomal subunit protein uS14
Sequence:
MLIPKENRKAIHQALFQQGVLVAKKDFNLPKHPEVGVPNLQVIKACQSLDSRGYLKTRYNWGWFYYTLTNEGVEYLREYLHLPAEVVPATHKRQVRPAAPRAGRPEPRERSSAADAGYRRAEKKDDGAAPGGFAPSFRGGFGRPVAA
Protein: UDP-2,3-diacylglucosamine hydrolase (EC 3.6.1.54) (UDP-2,3-diacylglucosamine diphosphatase) (UDP-2,3-diacylglucosamine pyrophosphatase) (P43341)
Organism: Escherichia coli (strain K12)
Function: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Is essential for E.coli growth. Does not cleave the unacylated UDP-GlcNAc, the mono-acylated UDP-3-O-(R)-3-hydroxymyristoyl-GlcNAc, and CDP-diacylglycerol.
Subcellular location: Cell inner membrane {ECO:0000305|PubMed:12000770}; Peripheral membrane protein {ECO:0000269|PubMed:12000770}; Cytoplasmic side {ECO:0000305|PubMed:12000770}. Cytoplasm {ECO:0000269|PubMed:12000770}.
Interaction partners:
- Lipid-A-disaccharide synthase
- UDP-3-O-
- Tetraacyldisaccharide 4'-kinase
- Lipid A biosynthesis myristoyltransferase
- 3-deoxy-D-manno-octulosonic acid transferase
- UDP-3-O-acyl-N-acetylglucosamine deacetylase
- Lipid A biosynthesis lauroyltransferase
- Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
- Peptidyl-prolyl cis-trans isomerase B
- Lipopolysaccharide assembly protein B
Sequence:
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
Protein: T-box transcription factor TBX20 (T-box protein 20) (Q9UMR3)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Homeobox protein Nkx-2.5
- Transcription factor GATA-4
- Heart- and neural crest derivatives-expressed protein 2
- Homeobox protein goosecoid
- Transcription factor GATA-6
- PHD finger protein 13
- Mitochondrial 2-oxodicarboxylate carrier
- Transducin-like enhancer protein 1
- Myosin-6
- Deoxyribonuclease-1-like 2
Sequence:
MEFTASPKPQLSSRANAFSIAALMSSGGSKEKEATENTIKPLEQFVEKSSCAQPLGELTSLDAHGEFGGGSGSSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGGEEDVLGDESQTTPNRGSAFTTSDNLSLSSWVSSSSSFPGFQHPQSLTALGTSTASIATPIPHPIQGSLPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLRHSSAVMTPFV
Protein: Purotoxin-2 (PT2) (OMICRON-lycotoxin-Am1b) (OMICRON-LCTX-Am1b) (B3EWH0)
Organism: Alopecosa marikovskyi (Wolf spider) (Lycosa kazakhstanicus)
Function: Enhances the high-affinity desensitization of human P2RX3 purinoceptors. At 50 nM, the toxin decreases the IC(50) for ambient ATP from 2.67 nM to 0.77 nM in human P2RX3.
Subcellular location: Secreted {ECO:0000269|PubMed:22842000}.
Interaction partners:
Sequence:
AKACTPLLHDCSHDRHSCCRGDMFKYVCDCFYPEGEDKTEVCSCQQPKSHKIAEKIIDKAKTTL