wanglab/gogpt-training-data huggingface dataset:
Protein: Rifin (Q8IIZ2)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKIHYINILLFALPLNILVNNQRNHNNSTYHTSNTKTIKSHRSLCECELYAQSNYENDQEMKDVIKEFNDRTAQRFEEYNERMQVKKDQCKEQCDKEIQQIILKDKIEKELTERFSALETKIDTNDILTCICEKSVTDKFEKTCLKCSGIFATAVPELGLIGGTVVYAAAVKAATKAGMEAALVGLESVNGLRGLLGEKIKDLVTTTNFQCPNALMGLVQNVKDTQCVGAAAQSQVFCKGLLPESTSRIIQKAAAAGREGAEAYNTTFSDSTTITAFLTDPIVISAIVVISIVVILLIIYLILRYRRKIKMNKKLQYIKLLKE
Protein: Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA synthetase domain-containing protein 1) (Q9BTE6)
Organism: Homo sapiens (Human)
Function: Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Alanine--tRNA ligase, cytoplasmic
- Putative protein PTGES3L
- Lysine--tRNA ligase
Sequence:
MAFWCQRDSYAREFTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDDRGTINDISVLRVTRRGEQADHFTQTPLDPGSQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIELDTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEVEQVSGRGLPDDHAGPIRVVNIEGVDSNMCCGTHVSNLSDLQVIKILGTEKGKKNRTNLIFLSGNRVLKWMERSHGTEKALTALLKCGAEDHVEAVKKLQNSTKILQKNNLNLLRDLAVHIAHSLRNSPDWGGVVILHRKEGDSEFMNIIANEIGSEETLLFLTVGDEKGGGLFLLAGPPASVETLGPRVAEVLEGKGAGKKGRFQGKATKMSRRMEAQALLQDYISTQSAKE
Protein: Putative calcium-transporting ATPase 7, plasma membrane-type (EC 7.2.2.10) (Ca(2+)-ATPase isoform 7) (O64806)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Lysine histidine transporter-like 5
- Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B
- Protein ABIL2
- Sulfate transporter 1.3
- Protein ABIL3
- Protein ABIL1
- Alpha carbonic anhydrase 7
- Protein ABIL4
- Sugar transport protein 9
Sequence:
MESYLNSNFDVKAKHSSEEVLEKWRNLCSVVKNPKRRFRFTANLSKRYEAAAMRRTNQEKLRIAVLVSKAAFQFISGVSPSDYKVPEEVKAAGFDICADELGSIVEGHDVKKLKFHGGVDGLSGKLKACPNAGLSTGEPEQLSKRQELFGINKFAESELRSFWVFVWEALQDMTLMILGVCAFVSLIVGIATEGWPQGSHDGLGIVASILLVVFVTATSDYRQSLQFRDLDKEKKKITVQVTRNGFRQKMSIYDLLPGDVVHLAIGDQVPADGLFLSGFSVVIDESSLTGESEPVMVTAQNPFLLSGTKVQDGSCKMLVTTVGMRTQWGKLMATLSEGGDDETPLQVKLNGVATIIGKIGLSFAIVTFAVLVQGMFMRKLSLGPHWWWSGDDALELLEYFAIAVTIVVVAVPEGLPLAVTLSLAFAMKKMMNDKALVRHLAACETMGSATTICSDKTGTLTTNHMTVVKSCICMNVQDVASKSSSLQSDIPEAALKLLLQLIFNNTGGEVVVNERGKTEILGTPTETAILELGLSLGGKFQEERQSNKVIKVEPFNSTKKRMGVVIELPEGGRIRAHTKGASEIVLAACDKVINSSGEVVPLDDESIKFLNVTIDEFANEALRTLCLAYMDIESGFSADEGIPEKGFTCIGIVGIKDPVRPGVRESVELCRRAGIMVRMVTGDNINTAKAIARECGILTDDGIAIEGPVFREKNQEEMLELIPKIQVMARSSPMDKHTLVKQLRTTFDEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKEIADVIILDDNFSTIVTVAKWGRSVYINIQKFVQFQLTVNVVALIVNFSSACLTGSAPLTAVQLLWVNMIMDTLGALALATEPPNNELMKRMPVGRRGNFITNAMWRNILGQAVYQFIIIWILQAKGKSMFGLVGSDSTLVLNTLIFNCFVFCQVFNEVSSREMEEIDVFKGILDNYVFVVVIGATVFFQIIIIEFLGTFASTTPLTIVQWFFSIFVGFLGMPIAAGLKKIPV
Protein: Protein simr-1 (siRNA-defective and mortal germline protein 1) (O01477)
Organism: Caenorhabditis elegans
Function: Acts downstream of piRNA production to promote mediator complex-dependent endogenous siRNA biogenesis from piRNA-target mRNAs in the RNA interference pathway in germ cells. Not required to identify target mRNA by the piRNA pathway. Plays a role in both spermatogenesis and oogenesis and in maintaining fertility over multiple generations, probably by directing mutator-dependent silencing to piRNA-targeted genes.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000269|PubMed:32338603}. Note=Localizes to perinuclear foci in germ cells, called SIMR foci, which are distinct from Mutator foci, P granules and Z granules (PubMed:32338603). SIMR foci are stacked, with znfx-1 localizing between simr-1 and pgl-1 (PubMed:32338603). Its localization at SIMR foci is adjacent to the mutator complex protein mut-16 (PubMed:32338603). Perinuclear localization is not dependent on mut-16 (PubMed:32338603). {ECO:0000269|PubMed:32338603}.
Interaction partners:
- NFX1-type zinc finger-containing protein 1 homolog
- MUTator
- Argonaute protein wago-4
- Protein pid-4
- Cyclin-dependent kinase 12
- Protein pid-2
- Protein pid-5
- RSD-2 domain-containing protein
- Protein hrde-2
- Protein F37C4.5
Sequence:
MSNEKQQWDDAYCLAEEMHDAGRPFKREELNIADQFICSRFSTIFEYDPYKDTYGFRNQELTHAIPVKSKCRHISDVDILELKKNTANADIRFPSYLNICPVYAMHPFTVLAFDLSKPVPMGMNASMENAAPNMKSPTEAEITPGTIYIFKHRDNKCYRCVILFEDGDNNVSDADRKYMVAFLDTPQVVSVKLKTLFHLGKFTIESYPCALYCCRAVGILEIRKDFGADLNGQINEFYKDKVKRKSGVHALIYKKDDRGDKLIFDCPSILGTSMTMALEIKDVIGHRSVAENDPTALSYDELVSKQLPTVDIDDHNSSVVLDLEESVIAQELGSTNGADCPCNNDNIDDFMQSQRQNPLDNNRDNWDRINESRSSMQSFAINQSQAITANPTPQPTFDESSGEVQTIPESINNLALNGRYLEDGRGTEEIREERSVESRQIGNQVVSQASCNYLEARQNSTQTANAESVCAIISESHAALPTDIQVIPSQHVLNENNHTVLPSVAPIIRNATGHSHIFGRQIPSPAFRRESLSSGNSIQVATFAATTGPCGSNTSRPTAQNTANSSINQDMSISNSSTNARLITIAQDNLNDTENWPNSEREQSATEMESGAEATTNSAVDEFAQVSDDMKGLADSMINFLRLTANSNNQDAFKANIFAMELISTKIPNQLTKRFFTLKIAEAKSLAEGFN
Protein: Chaperone protein dnaJ 3 (AtDjA3) (AtJ3) (Q94AW8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a continuous role in plant development probably in the structural organization of compartments.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Heat shock 70 kDa protein 4
- Heat shock 70 kDa protein 1
- Heat shock 70 kDa protein 17
- Heat shock 70 kDa protein 3
- Heat shock protein 90-2
- At5g64360
- FIP1[V]-like protein
- Heat shock 70 kDa protein 5
- Heat shock 70 kDa protein 10, mitochondrial
- Heat shock protein 90-3
Sequence:
MFGRGPSKKSDNTKFYEILGVPKSASPEDLKKAYKKAAIKNHPDKGGDPEKFKELAQAYEVLSDPEKREIYDQYGEDALKEGMGGGGGGHDPFDIFSSFFGGGPFGGNTSRQRRQRRGEDVVHPLKVSLEDVYLGTMKKLSLSRNALCSKCNGKGSKSGASLKCGGCQGSGMKVSIRQLGPGMIQQMQHACNECKGTGETINDRDRCPQCKGDKVIPEKKVLEVNVEKGMQHSQKITFEGQADEAPDTVTGDIVFVLQQKEHPKFKRKGEDLFVEHTLSLTEALCGFQFVLTHLDGRSLLIKSNPGEVVKPDSYKAISDEGMPIYQRPFMKGKLYIHFTVEFPDSLSPDQTKALEAVLPKPSTAQLSDMEIDECEETTLHDVNIEDEMRRKAQAQREAYDDDDEDDDHPGGAQRVQCAQQ
Protein: Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Q63100)
Organism: Rattus norvegicus (Rat)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Subcellular location: Cytoplasm {ECO:0000305}. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}.
Interaction partners:
- Cytoplasmic dynein 1 heavy chain 1
- Cytoplasmic dynein 1 light intermediate chain 1
- Dynactin subunit 1
- Cytoplasmic dynein 1 light intermediate chain 2
- Dynactin subunit 2
- Dynein light chain Tctex-type 3
- Dynein light chain 2, cytoplasmic
- Dynein light chain roadblock
- BICD cargo adaptor 2)
- Dynein light chain 1, cytoplasmic
Sequence:
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVPDDSDLDRKRRETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDDLGPLTRTLQWDTDPSVLQLQSDSELGRRLNKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVEPKVGHDSELENQDKKQETKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEGAYALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELAA
Protein: GH07340p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Q9VWL4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00037847}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00037847}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- LD25575p
- DnaJ homolog shv
- RE54691p
- Mitochondrial import inner membrane translocase subunit Tim16
- Endoplasmic reticulum chaperone BiP
Sequence:
MMMRPELTLAGLLLLCATGASAWHSEELEIFDLVEEVNRNFYEFMGINQTATGAEVKRAFRTLSIVLHPDKNPAEDANIQFRNLVSIYEVLKDPSRREKYDRVLKEGMPNWKSALYYYRRMRKIGLYEGAFILFLITTVGQYLFAWAAYLEKKYTAEQVFGTKLKKLQKKNKNIDMDVILSEIPMPSLLNTLPIQIPLALWNLPRTIKNGFSKANELKELALEKRRQELEAVRRQEELEREAEEQARLRKEHKENLRKRKQNSKAPEKTEEELRGYSQIQTRELTDDDAVRPASQKSTVSGGFWTDEDLTELIRLVKKYPGGAGSRWNTIAESMNRSVQEVTFMAAKMKENGYRIPGQTDSVAEALVQESQQAQRKEKVKKAAANAGASAEKSMLIPETNWTQEQQRALEAAIVKYRKTAGGDRWQKIANSVPEKTKEECLVRYKYLCELVKTQKRAEEEANEPDEDAAAIEEELPEEEPLAPPEPEVAPAAKKLSKREQRRRKRDLSSGEDSDDAYQYEIS
Protein: Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85) (Q9BZL4)
Organism: Homo sapiens (Human)
Function: Regulates myosin phosphatase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- Myosin regulatory light polypeptide 9
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Protein phosphatase 1 regulatory subunit 14A
- cGMP-dependent protein kinase 1
- Protein phosphatase 1 regulatory subunit 12A
- Rho-associated protein kinase 2
- Myosin light polypeptide 6
Sequence:
MSGEDGPAAGPGAAAAAARERRREQLRQWGARAGAEPGPGERRARTVRFERAAEFLAACAGGDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESDAMEGLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEEVLSLLEELARKQEDLRNQKEASQSRGQEPQAPSSSKHRRSSVCRLSSREKISLQDLSKERRPGGAGGPPIQDEDEGEEGPTEPPPAEPRTLNGVSSPPHPSPKSPVQLEEAPFSRRFGLLKTGSSGALGPPERRTAEGAPGAGLQRSASSSWLEGTSTQAKELRLARITPTPSPKLPEPSVLSEVTKPPPCLENSSPPSRIPEPESPAKPNVPTASTAPPADSRDRRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLDPSRRPRVPGVENSDSPAQRAEAPDGQGPGPQAAREHRKVGKEWRGPAEGEEAEPADRSQESSTLEGGPSARRQRWQRDLNPEPEPESEEPDGGFRTLYAELRRENERLREALTETTLRLAQLKVELERATQRQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK
Protein: Exocyst complex component EXO70B1 (AtExo70b1) (Exocyst subunit Exo70 family protein B1) (Q9FGH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of an exocyst subcomplex specifically involved in autophagy-related, Golgi-independent membrane traffic to the vacuole. Regulates autophagosome formation and autophagy-related Golgi-independent import into the vacuole. Positive regulator of both abscisic acid (ABA)-promoted and mannitol (drought)-promoted stomatal closure.
Subcellular location: Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:23944713}. Endomembrane system {ECO:0000269|PubMed:27956469}. Cell membrane {ECO:0000269|PubMed:35249253}. Vesicle {ECO:0000269|PubMed:35249253}. Note=Displays a punctate pattern. Colocalizes with PUB18. {ECO:0000269|PubMed:27956469}.
Interaction partners:
- Exocyst complex component SEC8
- Exocyst complex component EXO84B
- Exocyst complex component SEC5A
- Exocyst complex component SEC6
- Exocyst complex component SEC15B
- Exocyst complex component SEC3A
- Exocyst complex component EXO84C
- Exocyst complex component SEC10a
- Exocyst complex component SEC5B
- Exocyst complex component EXO84A
Sequence:
MAENGEEKLLAVARHIAKTLGHNESMADDILQIFSNFDGRFSREKLAEGQAGEDGSGVATLERALNSIDGQISRFVAADQPIWADPADSAAFLDTIDELVAIIREWSPMASEKPIGICLTRADDMMQQAMFRIEEEFRSLMERGAESFGLNPQGDAGAMNHRFDSEEEEDDDRDFNNGDDIQIPVAQPLTDYDLIIDALPSATINDLHEMAKRMLGAGFGKACSHVYSSCRREFLEESMSRLGLQKLSIEEVHKMPWQELEDEIDRWIKAANVALRILFPSERRLCDRVFFGFSSAADLSFMEVCRGSTIQLLNFADAIAIGSRSPERLFKVLDVFETMRDLMPEFESVFSDQFCSVLRNEAVTIWKRLGEAIRGIFMELENLIRRDPAKAAVPGGGLHPITRYVMNYLRAACRSRQTLEQVFEESNGVPSKDSTLLTVQMSWIMELLESNLEVKSKVYKDPALCYVFLMNNGRYIVQKVKDGDLGLLLGDDWIRKHNVKVKQYHMNYQRSSWNKMLGLLKVDNTAAGMNGLGKTMKEKLKQFNIQFDEICKVHSTWVVFDEQLKEELKISLARLLVPAYGSFIGRFQNLGDIGKNADKYIKYGVEDIEARINELFKGTTTGRK
Protein: Nicotinic acetylcholine receptor Dalpha7 subunit (Q8T5F4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MKKPSRSRPDNPSCPGQDRTRSMSFPQPHSLPEATANGGRMLVYGLGLLIMIPACAAGPHEKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQVTTQLLS
Protein: RE28359p (Zydeco, isoform A) (Q7PLW1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKYINCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKCAKGGVKQARSRSRSSNCSIHTKNSNEKEPELVENRICQNMANIQLNGGLNKEQAKATSTSGAGTTAISITTSTMTTTLSTTHSAGGGGGAVGLCSGPGAIVQMAPLDDAEAESHVAVAAADEGRKEEGYSLLSYPKDKSCFAQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVPWLIKAVFFPIQPGQNYVAINSAGLEYSAITLLSTLFLLYLTFSTNKFKLDKKVGTACLVMYLVFMVFASLIELNVFFRVNLPTCGRS
Protein: Myosin motor domain-containing protein (D3YT13)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNFAPPPTFTYPQQMPMMQYVPVMMTSSMMTPSMMTPSMMPGQQIAMVPQQMMMQPHFSYVPQYPQIPQYCPPEPILSPQSVRSEVPPMMAPVMHDGHGSTRSRDYRIMKRGEVPSQYSTIRNMPVPEHGKDVDQFLDAVFDQVLSKDEQRAAHFNSNQLANTIKGGKLRPEGYYEPPVQTYSPVPPRYPTLRRVDDSPLRSRAKSLPRIISPRHEHFVRRPHSRNSYSNESTSSDDQMNYRTRSRERSLPRFHSNNGYNYDPSQPVYMMPVQMNGHGEMILLSPVASEHKAQSRHRTHDRSHRHHVPSGVERYMAKRSPSVDILKPPMSRRTPDAMVEQTYVRPHLAQSPVGRQTSRFEEFSALPRGDSRARERMENPLLARQIPRAYPYQNGNVVPPPPSSYRAPSPAPTSGDRRGLNRLPQESYTEPAVKNTKNNSEYLSPHRFNLDEQKAVIRHEKETAKNAINMLSDRLRKLPPPVDNVRLIRPITPAQPPITQSPVPSEPVVVRTPSPVPQPTPPPPPPPVREEWVIRDSVERDPVTQGRIRGSFRKEPLVPQPPRPPVVAEKPAVKFVKAPWKLTIRKEMFYPGEVLNDIQIIDQVFAQIVEDCKKSYPYRIREQDRKQVETVLRQYEIPPSDLNNQSNIHPDVKVAVIELARLWPLYFNQVYEVVEKRPDESVSTIFAISEHGIRLIVHTPHDLENPLKIQDFFPFETIADVSLEANDILSVHVRHEDEENAYSAVRIKTNQAPQIKKTLDRCLSGGVVPKRKFVRALEDYVTSEVNHLSFKQGDVIELLQEPEGETPPVGNWLYGKIENRFGFLLAQYVDSTDGDNVPPIRHETSEDRDERVRFFDDEVPFSSERYTMIDFATKYFRKPKDKKKQETWAWEDISQIVRFSEKPISQSLLADLGNEESKYAVETFHAIMKFMGDEPLKKSESMTDVVFKVLLICHRQPTLRDEVYCQLIKQTTSNISQKPNSALRAWRLLTIITAYFPSSLTLKPYVLQYLGDNADEWQRPFHGTARICQTNMIQTFKYGGRKVLLNALEVQQITDGCQLRRQAFYISKDHNVSQTLRPITVAEEMIQELCNLLNVRSLHEQQEFSLCYTVGKDKHLNYCKNDNYLMDIITESEHKKLPFQFYLKRTVWVHPLRYDNAAYIDSMFDQVIDDYLRGSLISTNSLGQLTAATTEEIIKLAAYLFLLLPDNPKGLNAKTLPQIVPKSVIEPKHRHQEEMVTRISRQLKMFGGRMRPAEAKSHFLELLSTWPTFGVLHYRLKSVVENGHQLPEVILTINKSGIQLLQPKSKEVFKERNYDQIVSVESIRKTAYKIVRLVINTMQGEETLDIKTDEADEISHLIGQYMFVTGGAEERGSTEL
Protein: Betaine lipid synthase (Q6DN05)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Interaction partners:
- Ethanolaminephosphotransferase
- ethanolamine-phosphate cytidylyltransferase
- Acyltransferase
- Acyltransferase
- Acyltransferase
- UDP-sulfoquinovose synthase
- Uncharacterized protein
Sequence:
MGSGRDGRPASYTKKNFSLEKLKLSSMKDDLTVLRHMWFGSKKGDDHAARLESFYGPQAAAYDAFRSRFLWGRRPMLAAVAARLAERSNLIWVDLGGGTGENVDMMADYIDLAKFKSIYVVDLCHSLCEVAKKKAKAKGWKNVQVVEADACQFAPPEGTATLITFSYSLTMIPPFHNVIDQACSYLSQDGLVGVADFYVSGKYDLPLRQMPWSRRFFWRSIFDIDNIDIGPERRAYLEQKLERVWEQNTQGSIPYVPWLRAPYYVWIGRLPSVGHALHEERVERPPMFPPTFLYTQSWEDPEPDMEVMEINPKDTVLTLTSGGCNALNLLVQGAGQVVSVDCNPAQSALLELKKVAIQQLEFEDVWQLFGEGVHPRIEELYEKKLAPFLSQTSHNFWSKRLWYFQHGLYYQGGMGKLCWVLQCLAVVLGLGKTVKRLANAPTMEEQRRLWDSNMLIHFVKNGPKPLVWLFVKFVSLVLFNKAVLWFGGGVPGKQYALIKADGIPIENYIARTMDGVAENSHVRKQNYFYYNCLTGKFLRDNCPTYLREAAFATLKSGVVDNLTVSTNFFMEELKARTYTKVILMDHVDWLDMPVANELAECLAKQVAPGGIVIWRSASLSPPYAELIQKAGFDVRCIRRATQGYMDRVNMYSSFYMARRKGAKKDN
Protein: T-complex protein 1 subunit epsilon (CCT-epsilon) (O97282)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- CCT-beta
- T-complex protein 1 subunit eta
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit theta
- T-complex protein 1 subunit gamma
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit zeta
- Serine/threonine-protein phosphatase
- Phosducin-like protein 1, putative
- Cell division cycle protein 20 homolog, putative
Sequence:
MNIAIDEYGQPFVILREEEKKRIKGIEAHKSNILAAKVVADILKSSIGPRGMDKIIVSEDNNVTVTNDGATILEKIDVQHECAKLLVELSKSQDNEIGDGTTGVVIIAGVLLEEAYALIDKGIHPLRIADGFENACNIALKVIEDIALTVDIEENDHKILKKVAKTSLSSKIVSSKKDLLSNIVVDAVLSVADMKRKDVRFDLIKIEGKTGGLLEESTLIKGIVLNKELSHSQMIKEVRNAKIAILTCPFEPPKPKIKHKLNITNVDAYRDLQAIEKKYFYDMVASLKKAGANFVICQWGFDDEANYLLLKENIPAIRWVGGVEMELIAIATGGKIIPRFEDIDESKLGKADLIREISHGTVNNPMVYIEGCSNTKAITILLRGGNQMMIEECERSVHDALCSVRNLIRDNRILPGGGSTEIYAALEIEKVADKCKGIEQYAIRAFGNALLSIPINLCNNMGLNSIDIISEIKTKIIQDKTKNLGIDCLNYKVGDMIERGIFETFNSKYNQFSLATQVVKMILKIDDVIAPNDFN
Protein: TATA box binding protein (A0A8I5Y1F6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPVQNTNSLSILEEQQRQQQQQQQQQQQQQQQAVATAAASVQQSTSQQPTQGASGQTPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTA
Protein: Apoptosis regulator OPG045 (Protein F1) (P68451)
Organism: Vaccinia virus (strain L-IVP) (VACV)
Function: Plays a role in evading host innate immune response by inhibiting host inflammasome activation. Interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells. At the host mitochondria outer membrane, interacts with the BH3 domain of host BAK and prevents BAK from binding active BAX. In turn, host apoptosis is inhibited.
Subcellular location: Host mitochondrion outer membrane {ECO:0000250|UniProtKB:P24356}. Host cytoplasm {ECO:0000250|UniProtKB:P24356}.
Interaction partners:
Sequence:
MLSMFMCNNIVDYVDDIDNGIVQDIEDEASNNVDHDYVYPLPENMVYRFDKSTNILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDINNEVNTILMDNKGLGVRLATISFITELGRRCMNPVKTIKMFTLLSHTICDDCFVDYITDISPPDNTIPNTSTREYLK
Protein: Propionyl-CoA carboxylase, protein PccX subunit (PCC) (EC 6.4.1.3) (I3R7F2)
Organism: Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei)
Function: Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. PccX could be responsible for the interaction of the biotin carboxylase and carboxyltransferase subunits.
Interaction partners:
- Propionyl-CoA carboxylase, carboxyltransferase subunit
- Propionyl-CoA carboxylase, biotin carboxylase and biotin-carboxyl carrier subunit
- Acetyl-CoA C-acyltransferase
- Acyl-CoA synthetase
- 3-ketoacyl-CoA thiolase
- AMP-dependent synthetase
- Methylmalonyl-CoA epimerase
- acetate--CoA ligase
- 2-ketoglutarate ferredoxin oxidoreductase subunit beta
- 2-oxoglutarate synthase subunit KorA
Sequence:
MTEDLLSGLSIPDDADSEEAAAIAAAVGAHLHDQTAAAVAAAADEEETWDEKRWQYAGRLDSVTGCARRVPSGAPTNAWAASGRTDRF
Protein: CBS domain-containing protein CBSX5 (Q84WQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- SNF1-related protein kinase regulatory subunit gamma-like PV42a
- SNF1-related protein kinase regulatory subunit beta-3
- CBS domain-containing protein CBSX3
- CBS domain-containing protein CBSCBSPB3
- CBS domain-containing protein CBSX2, chloroplastic
- CBS domain-containing protein CBSX1, chloroplastic
- Sucrose nonfermenting 4-like protein
- SNF1-related protein kinase regulatory subunit gamma-1
- GMP synthase
- Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial
Sequence:
MALSLLSYNVSDLCLGKPPLRCLSSSSSSVSDAIAALKSSEDTFLSVWNCNHDDDNNTECECLGKISMADVICHLSKDHDHSLCALNSSVSVLLPKTRSIVLHVQPSCSLIEAIDLIIKGAQNLIVPIHTKPYTKKKQHNDNVSVTTTTHSNGQRFCWITQEDIIQFLLGFIAAFSPLPAMSLSDLGVINSTHTVVAVDYHSSASAVVSAVSNALAVQTSVAVVDGEGDDPFTSLIGEISPMTLTCCDETAAAAVATLSAGDLMAYIDGANPPESLVQIVRNRLEDKGLIGLMSLFDSLSSYSTSSGYSSEEEAPVRTTSYGRSMSSSARMARKSEAIVCNPKSSLMAVMIQAVAHRVNYAWVVEKDGCFVGMVTFVDILKVFRKFLENDM
Protein: ribonuclease III (EC 3.1.26.3) (A2RV16)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSFHAGRGCPRGRLPAPGQIYHPAPPRYHYDPSAAPGPVYNPQGGSSYMPPHPDFMSFHFPPPSQASNTLPQCPIRPPVFTEPPPFPPPPPHSSDGSTPMPIQNSYPYMMPNIPPPPLPPMPPSVPPTMPYPPTYPMSYPPQPQLPPPPSFNPAYGQPSGSFKPERSRPPLHYKTDSCSRSPERLRHHDDHRHRGHSYSEYGSRHNREFGGEKRDRGCSSERRRSDSPRRCKSDYDRGRVSSRHRSRDRYRHRDDPGSPSSDRHRKHARNRSGSRERKRRRVEEDKERRTDGSSSSRERSVNSSRSREAEEITIDRHEEDRGQEELHKPAWIRCTHAENYYSNDPMDQVGDSTVVGTSKLRDLYERFEEELGKRQERAKSIRPKWEPPKTKLDQDQDESSSESECESDGGGSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEQPVKQCRPMNNNAGKLFHYRITVSPPTNFLTDRPTVIEYDDHEYLFEGFSCFSHTPLTSIPLCRVIRFNIDYTIHFIEEMAPENYCVKGLELFSSYLFKDILELYDWNLTDPEENSPLGCQRFHFMPRFVRFLPDGGKEVLSMHQVLLYLLHSSKPLVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGMKPSSVRIDQLDREQFNSSVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQIDKQKLMQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYMFKERCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMYMRKKGINTLINIMSRLGQDDPSPSRINHNERLEFLGDAVVEFLTSVHLYHLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGGLEEAKDLFGRLLFNTEDMREVWLNYPPHPLQVQEPLTDRQLIESSPVLQKLTNFEDAIGVLFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEFAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEFVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRRERERQERDSDEG
Protein: Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.1) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2) (O00338)
Organism: Homo sapiens (Human)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Sulfonates p-nitrophenol, a small phenolic compond. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol. Catalyzes the sulfonation of the carcinogenic N-Hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O46503}. Lysosome {ECO:0000250|UniProtKB:Q9WUW8}. Mitochondrion {ECO:0000250|UniProtKB:Q9WUW8}.
Interaction partners:
- Sulfotransferase 1A1
- Sulfotransferase 4A1
- Sulfotransferase 1A2
- Sulfotransferase 1A3
- Sulfotransferase 1C4
Sequence:
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVARNAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILFLFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSILDQSISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFCMEL