wanglab/gogpt-training-data huggingface dataset:
Protein: Neurofibromin-A (DdNF1) (Q55AR6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Regulator of the GTPase activity of Ras, mainly RasG and RasB.
Interaction partners:
- Ras-like protein rasG
- Ras-like protein rasD
- Ras-like protein rasB
- Ras-like protein rasC
- Protein VASP homolog
- RGS domain-containing protein
Sequence:
MDVDKQMLQWRKRAWLNSNQLYGELTDIIIKDTGFTSSFANLIDNSEVDSFSKNIVNIFTTANKTLPLIKDLIYNEFNTKVLAEGEGSILRGNSIVNKIEGAYVRLIGANYLRFVLSDLVTKVVLDSDLKLEIDPRKLNDYYEDKIEFEKKVAEVELRDNQKSLHNIAQQFLDRITDPSVVVEMPREIRAIADYTAESALRYAPESLAPLVGGFIMLRFFSPAIVTPEYSKLLSSEVAPSKRAKRNLVLLAKVLQNASNGVLFGGKEEFMTCMNDFIIGNKEKMSAYFNLICKDPLNQNNKWSDLEGVKSATTTTTILTPTNTTTSSNGSGGTTWAKPIVGGSKWLATTPSGNTPSPAISNASSAHNGKSNNTTNNNNNNNNNNNNNNNNNNNNNNNSNKTTTTATTISSNSWDVYIKNVQIQDLFDLHRIFDSYKEKIVNKIINTNNNNANNANNNNTNNINNKTAIRVIEILKELGPSPKTKTERKKKETDAAEEPTTSLQNGASMGSAFDECTHMLERSRFLFQGPNDKNDRSVFYLIVNRVKPEVFDNVNPLIAHIFKVMDICVNSPYTLVVDMSWAHISNDLKKAIFTHLPKLAEIFSRKYKKNIDKIFIVHPSAYTRAVIYFMSAFTSRKLKRKIHDIYNWKDLSQYIDIENIALPETSKDFITKSYRVVKVNSKGKRQERLIKFTSNSLLNIDPKTHRIQNEKRINEIDEITSRLGSIEINMKLSGESKKSGSILGTKIGFLSINNNNNNNNDDSNGNHDINESNSRKYICNHELERDHILQDIFETGFKMGLQSKSTKSLPTEYKVIKVNNVGKHQERIFKLTIDSLLNLDQQRIKSENSFAGIEEVILDPHDDDIVWLKFKSEPSRRKIICTVKGEGKLLLEVLTDAINKYQTTIDIQEGALKLDAEEGFL
Protein: Dizzy isoform AII (Gef26 dizzy AI isoform) (PDZ domain-containing guanine nucleotide exchange factor, isoform A) (Q9VMF3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ras-related protein Rap1
- GTP-binding protein Rheb homolog
- small monomeric GTPase
- DE-cadherin
- protein-tyrosine-phosphatase
- Tyrosine-protein phosphatase
- Canoe, isoform E
Sequence:
MDPYHHIRHHYPPTSIAGTGVVVGSSTTINRPELHQKCNRGSHSSDTSSAYSGSDTMASNYASSLEAEEIDLSGLVESVVDSDEEDLAESMDSLTVRDAVRDCLEKDPAERSEEDVEVLLEFTQGLKAFTNITLAVRRALCSVMVFAVVDKAGTVVMSDGEELDSWSVLINGAVEIEHANGSREELQMGDSFGILPTMDKLYHRGVMRTKCDDCQFVCITQTDYYRIQHQGEENTRRHEDENGFVVMVTELRSIGGAGTDSAGSGGSATGASASLNMKRGHVVIRGTPERLLQQLVEENSMTDPTYVEDFLLTHRIFIQNPQEVTSKLLHWFDLEQVDAHKTQELRDRVTRVVLLWVNNHFTDFEADYEMMEFLEVFEALLERKKLLSQLRLLHIACAAKARMRSCTLTRSSRDEPLNFRIVGGYELRGVAIATGNAAVGIYISHVEPGSKAQDVGLKRGDQIHEVNGQSLDHVTSKRALEILTGTTHLSISVKSNLLGFKEIMQALEHGGGTAGSGSISAGSGSFKSVRSPRRICANDIAKLHGRSDSTTDELSSVSASNRAHMVRLSSVDMLLDQPDCAPPQTPPVSGSGNMASNFMQQLLQSVNNSSAKKSGGNSNSDQQDTKGGFMTLAPKRRLQKALAKMNLLNKQNHGSSLNDSSDTLLNDPKSKLSAVSSCSSSTQSSINGCTVSGGGRLYQSQSNPDLTSLNYDGGSDAGGNGGGRLQVNYLNAHIHRPSAASTLTTNSTQSHLLPDYPDHVLKVYKADQTCKYVLIYKETTAHEVVMLTLQEFGIHDPSSNFSLCEVSVGDGGMVKQRRLPDQLQNLAERISFAARYYLKLNDSTEPLVPDELALELVRESNVHFLHLNAYELAIQLTLQDFANFRQIESTEYVDELFELRSRYGVPMLSKFAELVNREMFWVVSEICAEHNIVRRMKIVKQFIKIARHCKECRNFNSMFAIVSGLGHGAVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAELLAQHPIIPFYPIVKKDLTFIHLGNDTRVDGLINFEKLRMLAKEVRLLTHMCSSPYDLLSILELKGQSPSNALFSLNQMSASQSNAAAGTVIAANAGQATIKRRKKSTAAPNPKKMFEEAQMVRRVKAYLNSLKILSDEDLLHKFSLECEPAHGSTYSGSISHGNTSHRSGGGGSISGGAGGSSGGGGGGSSSLNAGDQLSIYSHTSSSSAPNSSLSLRKRHPSSPTLSTTSSTSSTSDHQRRQMHNNGPKFGTASPQAVKKMLSLSESSKIRPHQPFVPRHGSTMAGVIPPLHHMHAAHGFSTPSPGGVVTSPATSAVANVQCTPSPSPCSHRRLASGGNIIPSRAIHERSHSDTPAPPPPLPSVDLSLESSSVTTFRDLPLRKSVTSGSISSCDSGYVHQQQHYHLQYQQQQQQNSSQHEPSPPVYTAADCRLLQQISNNAVTRNLNSPCQSTNTPPSTPTPPPNQPTATIQLSAPPTAAAYMHARSQHQQLQQQQQSLAMPPPPPPPYNVPPLGSIYSHHQGTAGSRHLNHMHGKTTGPQERWFPDCRPTTKQQMQSGS
Protein: Antitoxin VapB21 (P9WJ43)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC21.
Interaction partners:
- Ribonuclease VapC21
- Ribonuclease VapC42
- Putative antitoxin VapB42
- Possible type I restriction/modification system specificity determinant HsdS
- Winged helix-turn-helix domain-containing protein
Sequence:
MHRGYALVVCSPGVTRTMIDIDDDLLARAAKELGTTTKKDTVHAALRAALRASAARSLMNRMAENATGTQDEALVNAMWRDGHPENTA
Protein: Forkhead box protein D3 (HNF3/FH transcription factor genesis) (Hepatocyte nuclear factor 3 forkhead homolog 2) (HFH-2) (Q61060)
Organism: Mus musculus (Mouse)
Function: Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- POU domain, class 5, transcription factor 1
- Transcription factor SOX-10
- Paired box protein Pax-3
- Transcription factor SOX-2
- Zinc finger protein ZIC 1
Sequence:
MTLSGSGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPDLRLDEADEGPPVSAHHGQSQPQALALPTEATGPGNDTGAPEADGCKGGEDAVTGGGGPGAGSGATGGLTPNKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALMMQSFGAYSLAAAAGAGPYGLHPAAAAGAYSHPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPSLQLQLNTLGAAAAAAGTAGAAGTTSLIKSEPSARPSFSIENIIGAGSAAPGGSAGGGGSGGGAGGGGGSGGGGGAQSFLRPPGTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAVQAKWPAQ
Protein: C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369) (Q6QLQ4)
Organism: Mus musculus (Mouse)
Function: Lectin that functions as pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and activation of NF-kappa-B: upon beta-glucan binding, recruits SYK via its ITAM motif and promotes a signaling cascade that activates some CARD domain-BCL10-MALT1 (CBM) signalosomes, leading to the activation of NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation. Induces phosphorylation of SCIMP after binding beta-glucans.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10779524, ECO:0000269|PubMed:15213161}; Single-pass type II membrane protein {ECO:0000269|PubMed:10779524, ECO:0000269|PubMed:15213161}. Note=Enriched on zymosan phagosomes. Enrichment does not depend on opsonization.
Interaction partners:
Sequence:
MKYHSHIENLDEDGYTQLDFSTQDIHKRPRGSEKGSQAPSSPWRPIAVGLGILCFVVVVVAAVLGALGEYGHNSGRNPEEKDNFLSRNKENHKPTESSLDEKVAPSKASQTTGGFSQPCLPNWIMHGKSCYLFSFSGNSWYGSKRHCSQLGAHLLKIDNSKEFEFIESQTSSHRINAFWIGLSRNQSEGPWFWEDGSAFFPNSFQVRNTAPQESLLHNCVWIHGSEVYNQICNTSSYSICEKEL
Protein: Acetylglutamate kinase (EC 2.7.2.8) (N-acetyl-L-glutamate 5-phosphotransferase) (NAG kinase) (NAGK) (P9WQ01)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00082}.
Interaction partners:
- N-acetyl-gamma-glutamyl-phosphate reductase
- Argininosuccinate synthase
- Acetylornithine aminotransferase
- Ornithine carbamoyltransferase
- Arginine biosynthesis bifunctional protein ArgJ
- Arginine repressor
- Argininosuccinate lyase
- Amino-acid acetyltransferase
- Nitrogen regulatory protein P-II
- Probable histone acetyltransferase Rv0428c
Sequence:
MSRIEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGRIPVVSTLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDRDSLVSEIDTGTLAQLLPTLESGMVPKVEACLRAVIGGVPSAHIIDGRVTHCVLVELFTDAGTGTKVVRG
Protein: U3 small nuclear ribonucleoprotein (SnRNP), putative (Q583Q6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- AATF leucine zipper-containing domain-containing protein
- U3 small nucleolar RNA-associated protein 18
- HEAT repeat-containing protein 1
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- Bms1-type G domain-containing protein
- rRNA biogenesis protein, putative
- U3 small nucleolar ribonucleoprotein protein MPP10, putative
- Nucleolar RNA binding protein, putative
- Small-subunit processome Utp21 domain-containing protein
Sequence:
MRRSVIRQRKEFLERRQNEHVHAAIYTKKEQFRDAIQNATPLPGHLRKDALALKKFSELDDDQTKVLQTTVDDEYAKAGVEDPHVLVTTSREPSQKLLEFAKEVRLIIPNAVRLNRGNLNIRQLMEAARRDQYSDVVVLQESQGVPDSLTISHLPLGPTVVFTIHNLVTRHDIEDVGTMSEQYPHLIFENFTTKLGCRIRDVLKYLFPVPKPEATRVLTFDNQNDFISFRHHTFKMVKKSNVQLTEVGPRMELSPCRIMLGTLEMDDAETEWVLQPYMNTAKKRRLM
Protein: N-carbamoylputrescine amidohydrolase (Q9I6J8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Agmatine deiminase
- ornithine decarboxylase
- Polyamine aminopropyltransferase 1
- Polyamine aminopropyltransferase 2
- Transcriptional regulator AguR
- Putrescine--pyruvate aminotransferase
- Spermidine acetyltransferase
- Secreted protein
- Fe2OG dioxygenase domain-containing protein
- S-adenosylmethionine decarboxylase proenzyme
Sequence:
MTRNVTVAATQMACSWDRPANIARAEKLVRQAAARGAQIILIQELFETPYFCQKPNPDYLQLATTVEENAAIAHFQALARELQVVLPISFFERAGRARFNSIAVIDADGGNLGVYRKSHIPDGPGYHEKYYFNPGDTGFKVWQTRYARIGVGICWDQWFPESARSMALLGAELLFYPTAIGSEPHDASISSRDHWQRVQQGHAGANLMPLVASNRIGREEQDGYDITFYGSSFIADPFGEKVEELNRTEEGILVHTFDLDALERTRSAWGVFRDRRPNLYGPLKTLDGSLES
Protein: Rifin (Q8IM83)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKVHYTKILLFSLPLNILVTSSSNAHSKNKTYITLRHTPPIKSRVLSECDLYIPKYDNDAEMKSVKGTFDRQASQRFEEYEERIKDKRQKRKEERDKDIQKIILKDKVEKSLAEKVEKGCLKCGCGLAGVATSVSIIGPIAVNEWTKAALLSAKSSAIAEGNIKGIEAGVNAGIKAVIDGLKSKFSLDIVAGKALEDLVTKTTYLNKNLLSEPFHIQYQSMCVGPTADIDKPLCAFNIKNDTTWALKAIDGNVEKIISEAIKTTDTVTSNVTASEIPSIEALEKAAIEITCSNFHTAIIVSVVAILVIVLVMVIIYLILRYRRKKKMNKKQQYTKLLNQ
Protein: Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B) (P61956)
Organism: Homo sapiens (Human)
Function: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. Plays a role in the regulation of sumoylation status of SETX.
Subcellular location: Nucleus. Nucleus, PML body.
Interaction partners:
- SUMO-conjugating enzyme UBC9
- Ran GTPase-activating protein 1
- Sentrin-specific protease 1
- SUMO-activating enzyme subunit 2
- E3 SUMO-protein ligase PIAS4
- E3 SUMO-protein ligase RanBP2
- SUMO-activating enzyme subunit 1
- Sentrin-specific protease 2
- E3 ubiquitin-protein ligase RNF4
- BRCA1-A complex subunit RAP80
Sequence:
MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY
Protein: Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Proline dipeptidase) (Prolidase) (P21165)
Organism: Escherichia coli (strain K12)
Function: Splits dipeptides with a prolyl residue in the C-terminal position and a polar or nonpolar amino acid at the N-terminal position. With much lower efficiency, also catalyzes the stereoselective hydrolysis of a wide variety of organophosphate triesters and organophosphonate diesters. Is able to hydrolyze the organophosphorus insecticide paraoxon and the p-nitrophenyl analogs of the nerve agents GB (sarin), GD (soman), GF, Vx and rVX.
Interaction partners:
- IMPACT family member YigZ
- Methionine aminopeptidase
- Aminopeptidase N
- Peptidase T
- Cytosol non-specific dipeptidase
- Trk system potassium uptake protein TrkH
Sequence:
MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
Protein: RuvB-like helicase (EC 3.6.4.12) (Q8IIU3)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RuvB-like helicase
- DNA methyltransferase 1-associated protein 1, putative
- Zinc finger protein, putative
- Probable ATP-dependent helicase PF08_0048
- Actin-related protein, putative
- DNA repair protein RAD5, putative
- PIH1 domain-containing protein, putative
- Nucleolar protein 5, putative
- YL1 nuclear protein, putative
- Histone H2A
Sequence:
MEINISNITNSSNNKKERVNIHSHIKGLGVNTNIYLHENEISLSDEKYSMFFDNSCGLVGQFKAREASLFLVDLIKQKKLAGKCILLAGPSGSGKSALAIGISREINRKMPFVFLSGSEVYSNEIKKTEVILEAFRKSIHIKIKEEKLVYEGEVVDMVVEENECLYSLNKAKQINAIIITLKSVKGSKTLRLAPKIHEQIAREKIKIGDVIYIETNTGHVKRLGRCNDYAKEYDIEFDEYVSLPKGEVHKKKEVVQQISLHDIDLANANPTVGEDLASVLNSYLRPKKTEITEKLRVEINKTVNKFLESGLAEIIPGVLYIDEAHMLDIECFSYLNRAIESPLAPILIMATNRGICTVKGTDNIEPHGIPVDLLDRLIIIKTFPYTLKEIVQILALRAQTEKINITEEGMNYLAKIGIQSSLRFAMLLLEPSRILATLEGNTIIDIKHIEQADELFMDAKTSAHRVVDQSNKFVN
Protein: Collagen alpha-1(X) chain (Q03692)
Organism: Homo sapiens (Human)
Function: Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Collagenase 3
- Collagen alpha-1
- Runt-related transcription factor 2
- Aggrecan core protein
- A disintegrin and metalloproteinase with thrombospondin motifs 4
- Collagen alpha-2
- Stromelysin-3
- Transcription factor SOX-9
- Integrin-binding sialoprotein
- Collagen alpha-1
Sequence:
MLPQIPFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM
Protein: Phosphatidylinositol 3-kinase pik3 (PI3-kinase vps34) (PI3K vps34) (PtdIns-3-kinase vps34) (EC 2.7.1.137) (Vacuolar protein sorting-associated protein 34) (P50520)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Phosphatidylinositol 3-kinase homolog required for vacuolar sorting and segregation.
Interaction partners:
- Vacuolar protein sorting-associated protein atg6
- Vacuolar protein sorting-associated protein 38
- Serine/threonine-protein kinase vps15
- Serine/threonine-protein kinase atg1
- PtdIns3K complex I subunit atg38
- 1-phosphatidylinositol 3-phosphate 5-kinase fab1
- GTP-binding protein ypt5
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Autophagy-related protein 101
Sequence:
MDRLVFSYCPSSKVTARFLVKFCFIEYQDSQEPCICTIQLFSGNESGSLMQKCFVSKIPNKSLLPTELSKISTHEWLDFGVTVSELSLNAKFVVSAWKPSFNDEEVYEFVGCTTYRLFDENNLLRQGLQKIPLQTSKEIKKYSPTSLELEQVKEINRLDGLLLKLQLGDVPSVNWLDDISFGKIKDFRSKHMSLVTIPILYLDFLQFSFPVVFQRSYYPKSENRVYYSSFDLELNLDSPAELKHRRLVRSQRNGPLDKDLKPNSKIRKELESILSYPPSEELSLEEKDLIWKFRFYLTRNKKAMTKFLKSVVWTDSSEVNQALSLLDSWTEIDIDDALELLSPSFVHPKVRAYAVSRLETASNEELLLYLLQLVQALRYDNPISSDERFQPSPLALFLVNRAISSPSIGNDLYWYLVVEIEDEPVSKLFSSVMFLFQKELSKSVEGRLIRETLSAQAKFVEKLLRISKSVQSFRGTRLKKIEYLKVLLEDHKYHLLDFHALPLPLDPSVNIVGIIPDACTVFKSTMQPLRLLFKCQDGSKYPIIFKNGDDLRQDQLVIQILTLMDKLLKKEKLDLHLKPYRILATGPTHGAVQFVPSKTLATILAEYHGSVLAYLRENNPDDGLNSANYGIDPVAMDNYVRSCAGYCVITYLLGVGDRHLDNLLITKDGHFFHADFGYILGRDPKLFSPAMKLSKEMVEGMGGYNSPFYQQFKSYCYTTFTALRKSSNLILNLFSLMVDANIPDIKFDKEKVVYKVKERFCLQMSESDAIKYFEQLINDSVSALFPQIIDRMHNLAQYMRS
Protein: Neuroligin 1 (Neuroligin-1 isoform X3) (Neuroligin-1 precursor) (B6EUL6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MPFQQPNRLSSIWKAMCPRLGLSASLDLPFLCWIVGLALHAQLAASEKLDETDPIVTTTYGKVRGFKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIRNATQFAPVCPQTLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKKICRKGDIRESGSPKPVMVFVHGGSYMEGTGNMFDGSILASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLAKKVGCNLKDTVEMVECLQKKHYKELVEQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVELIVDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSSFGSPTYFYAFYHHCQTEQVPPWADAAHGDEIPYVFGLPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYNQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHSLNEVSQIISTTKLPPPEVTPRTPKKIPVNTKRPYPTPFPTETQDSHNQNQNQPFLVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHEVHRRCSPQRTTANELPHTQEEEIMSLQMKHSDLERECREAMHPHEVVLRTACPPDYTLAMRRSPDDIPLMTPNTITMIPNSMPGLTSLHPFNSYSSGQNNTLPHPHPHSHSTTRV
Protein: Synaptobrevin-type vesicle transport protein, putative (Q387Z8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00046280}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00046280}.
Interaction partners:
- Syntaxin 5
- SNARE protein, putative
- t-SNARE coiled-coil homology domain-containing protein
- Golgi vesicular membrane trafficking protein, putative
- Vesicle-associated membrane protein, putative
- Golgi SNARE protein-like
- Vesicle transport v-SNARE N-terminal domain-containing protein
- Sec1 family transport protein, putative
- Longin domain-containing protein
- Protein kinase
Sequence:
MASKGCFIAVLIARTHDHVPLCSFTDENYANWNQIRQQEQRILERMESPASVPDSAGTRGSYYQSFDHKDCIYFAFQDAGTGLTIITVLNKLLLRNSSDVTSTNHLACSLLDMIFSEFTQAYSTSEISARTVRPFQFIKFESTLEKLIHRVQRERQNDVVSDSHGGQRRQVNTQYDAIKQELTDVHFVMRKNLEDLMVRGEKLETMNQFSAQLVDESSRFYKKTARMNRMRLLKLYGPPAVVISILALFFYLYLF
Protein: KapC (C8VUP5)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- GTP-binding nuclear protein
- Nuclear polyadenylated RNA-binding protein Nab2, putative
- Peptidase S59 domain-containing protein
- Importin subunit beta-4, putative
- Importin beta-3 subunit, putative
- Nucleoporin NSP1
- Heterogeneous nuclear ribonucleoprotein HRP1
- RNP domain protein
- Nonsense-mediated mRNA decay protein
Sequence:
MQWQPEEGPLGQLAYCFRDSLNSHNSAAQKQAEQMLVQATSSPDYVKYITYLFCTPQKPSVLNMQPAEYDIVRVAAAMNLKMKIHVAYNTIPQDSLAYIRSATLIGLRDDNGQVRNSAGIVITELIAKAGLLAWPEVLHELLTLVENPAGDASTTTREAAMSALFKVCEDNRKILEREYSGQCPLDVIIPKLLSFSSIDSFRIRESALKAILIFLPHRPKSLIAQMDVFLSQLFQLSNDPSLEVQRTVCQAFAQLVDFAPEKLIPHMDGLVNYIIMQQQSQIDPELNLDAAEFWLVAGEQAALQQPLAPHMPKIVPVLLQSMVYDEEEAIRLAGEGEDADVEDREEDLKPQFARSKASRMDVSKAGGQQNGNASAQAPEDEDDDLSEGEIEDSEFGDDPEDEWTLRKCSAAALDVFSNVYHEPIFEIILPYLKETLRHEQWVQREAAVLTLGAVADGCMDAVTPHLPELIPYLISLLNDTQPVVRQITCWCLGRYSEWASHIADPAERARFFEPMMEGILRRMLDGNKKVQEAAASAFASLEEKSDANLIPYCEPILRQFVLCFGKYKDRNMYILYDCVQTLAECVMGELGKPHLVEILMPALIDRYNKVSDQSRELFPLLECLGYVAAAYGDTFAQFAPPLFQRCTKIIYENLQEYVASVNNNTIDEPDKDFLVTSLDLLSAIIQAIDPNKSGELIVNSQPRFFDLLCFCMEDPNYEVRQSSYALLGDCAMYIFPQLEPFINNIMPILIKQLDLDMIRDDDRHTGFSVLNNACWSCGEIAVNEKAALAPYAEKLYHGLLAIINNEEIIDSVNENAAMALGRLGICCSDQLAPRLAEYAGTFLKSMSRIDFTREKASAFLGFNQVVMKNPAAMESSLVDYFQAIAAFPSKSLHQDEYHDIQSSFQQVLQGYKNMIPDFDSFMSQLPPPVAQKLRSVYQI
Protein: Probable glycerol-3-phosphate acyltransferase (G3P acyltransferase) (GPAT) (EC 2.3.1.15, EC 2.3.1.n5) (Lysophosphatidic acid synthase) (LPA synthase) (P60782)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4) (Probable).
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Phosphate acyltransferase
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate acyltransferase
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- Aerobic glycerol-3-phosphate dehydrogenase
- Glycerol kinase
- Anaerobic glycerol-3-phosphate dehydrogenase subunit A
- Anaerobic glycerol-3-phosphate dehydrogenase subunit B
- Anaerobic glycerol-3-phosphate dehydrogenase subunit C
- Bifunctional protein Aas--phospholipid O-acyltransferase); Acyl-[acyl-carrier-protein] synthetase
Sequence:
MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
Protein: Small ribosomal subunit protein uS2 (40S ribosomal protein SA) (K14) (Laminin receptor homolog) (Protein stubarista) (P38979)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Required during oogenesis and imaginal development.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015, ECO:0000269|PubMed:12150910}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03015, ECO:0000269|PubMed:12150910}. Note=May associate with nascent RNP complexes within the nucleus.
Interaction partners:
- Small ribosomal subunit protein uS14
- 60S ribosomal protein L27
- 40S ribosomal protein S27
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL13
- Small ribosomal subunit protein eS10A
- Large ribosomal subunit protein eL21
- Large ribosomal subunit protein uL6
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein eL38
Sequence:
MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNILNLGKTWEKLQLAARAIVAIDNPSDIFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPNTDHQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRSVEWPVVVDLFFYRDPEEAEKEEAAAKELLPPPKIEEAVDHPVEETTNWADEVAAETVGGVEDWNEDTVKTSWGSDGQF