wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial ATP-binding cassette 1) (M-ABC1) (Mitochondrial sulfonylurea-receptor) (MITOSUR) (Q9NUT2)
Organism: Homo sapiens (Human)
Function: ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane. Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:16259955, ECO:0000269|PubMed:31435016}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
- Mitochondrial potassium channel
- Mitoferrin-2
- ATP-binding cassette sub-family B member 6
- ATP-binding cassette sub-family A member 2
- Lysosomal cobalamin transporter ABCD4
- ATP-binding cassette sub-family G member 5
- ATP-binding cassette sub-family G member 8
- Mitoferrin-1
- Potassium-transporting ATPase alpha chain 2
- Sodium/potassium-transporting ATPase subunit alpha-3
Sequence:
MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRNTWRNGKTGQLHKAEGEYSDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKGGLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS
Protein: Coiled-coil domain-containing protein 107 (Q8WV48)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAGAVSLLGVVGLLLVSALSGVLGDRANPDLRAHPGNAAHPGSGATEPRRRPPLKDQRERTRAGSLPLGALYTAAVAAFVLYKCLQGKDETAVLHEEASKQQPLQSEQQLAQLTQQLAQTEQHLNNLMAQLDPLFERVTTLAGAQQELLNMKLWTIHELLQDSKPDKDMEASEPGEGSGGESAGGGDKVSETGTFLISPHTEASRPLPEDFCLKEDEEEIGDSQAWEEPTNWSTETWNLATSWEVGRGLRRRCSQAVAKGPSHSLGWEGGTTAEGRLKQSLFS
Protein: GH24564p (TipE homolog 1, isoform A) (TipE-like protein 1) (Q9VH54)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRSGSSELLLEQQQQELRLRKIRELAPKKKNGNRRFRSWRERARFYGTSTLAFFSVTAGASLLFLVPLYVDPAISTLSHDFIEKPTLCTTTRREDLVGIFNCSWSSCREGCTSDLYRCVHIYVTFIEQNITIPENMTDYSNFTSDMEQSGEATLLVNIKGCGYPPSVTCKNFNGYYGIEGAIFPCFYSRKNKTVVLTSYNHDDQVAMIIHFFAVPFVITVISSIALCIMHCDCRCKKDRSHRRNRPQCRRPRIENLSDTSISTRVDMLTPAIEVYKPPL
Protein: Uncharacterized protein C12G12.09 (Q09872)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- RNA-binding post-transcriptional regulator cip2
- Deadenylation-dependent mRNA-decapping factor pdc2
- mRNA-decapping enzyme subunit 1
- 5'-3' exoribonuclease 1
Sequence:
MSFYKEKSINETNLGSFVDESNELFFSALSESSMNHGTPDDSILLDLVSRSDNKDLYQDSLDVRDNFSNLSSDEIPQSSSYEQTRKPFFHHFNPFEFLEATSPLQQNGKSRDTEKPPSMKEKDLSSNSSSQHDKAFHERVDQGKNKSSTTKYQEFRTVADYREFSPGQSVNSLKPNSGDEVPSTKSSTSSEMHTQLLKDEQKKILTPAPDVPHDVYCIEPSLGRVFSFPASFVASPLLLEDCNKIASCDLPYSTFYANSQVIDKFSEYFAYVDQDPCHIRVLNANTDQSLILYTQSDVKNLHFGKNKHTKPHLLVMDALSNLYVWKILQKRSEISVSLLFTIRRANYGICDWIPNSSNMFSMIVKNSLYIVDISNIRSNNISPKVYAKDFNGLQAAKVDLPGPINSYTISSDRSVVAILVNSQIFFYSFPVSNLFSTNPSHRGNWAAIATMSLQLPSTANSISFLSSPPNNNDIIDKVICVSYANNTILGLFDFGLCAFTQEIEFSNEKEKSPIQQLLTFNNSNMIVAKRNQLLDIFIYSPSDLSNVGVLSNTAALISAVSKGKRFGDSGYINKVISNEVVDHSIVFVTLIGCDSSKLELILALSSGYFQFCIESDSKFDEGTSLEYPNSDKRILARASLTSGLKSNNTLRALSQDLKNCAKSKDDSTTQNLTESLGSVCYPSMPFFNQYVPQNPNEVRENISSVMKSRIHAKFESLHSRVELVVKNSYMKLLEQTISEAATDEISDLFKLIHSKPFLLEVGFLETGFLANDLENLTSTYRSSNRQLCDFSNRIGNINQKLEKLLMIERLETSDQSPTSSSNFEESESFAVSKKVLELVRISKNKEALICFTKDPSIEAFRSLQDVPDYSLDDCSSIHLLAFIHVLSKLIIKEEQLSFSRLQLLSRATSRLRTMTLSVFNNSGTLTPELFSSVVRIVLKNVREFVLIGNSSIQKSKHEFLITTLQALLREVDIFLNT
Protein: Cyclic di-GMP phosphodiesterase response regulator RpfG (EC 3.1.4.-) (Q4UU85)
Organism: Xanthomonas campestris pv. campestris (strain 8004)
Function: Member of the two-component regulatory system RpfG/RpfC, which is involved in the perception and response to the diffusible signaling factor (DSF), which is essential for cell-cell signaling. Detection of DSF leads to the positive regulation of biofilm dispersal and the production of virulence factors. Activated RpfG degrades cyclic di-GMP to GMP, leading to the activation of Clp, a global transcriptional regulator that regulates a large set of genes in DSF pathway. May also directly control genes involved in biofilm dispersal.
Subcellular location: Cytoplasm {ECO:0000305}. Note=Localizes predominantly at the cell poles. {ECO:0000269|PubMed:20231439}.
Interaction partners:
Sequence:
MQDVLGNPAGVSSAETWGSWSEKADLGLNIVIVDDQMSARTMLRHVIEDIAPELKVYDFGDPLDALSWCEAGRVDLLLLDYRMPGMDGLEFARRLRRLPSHRDIPIILITIVGDEPIRQAALEAGVIDFLVKPIRPRELRARCSNLLQLRQQSESVKQRALSLEQRLLASMNEVEERERETLSRLARAIEYRDGGTSAFLERMSHVAGLVAEQLGLSEEEVRIIEMAAPLHDMGKIAIPDSVLLKPGKLTEDEMNVMKRHPRIGYELLSGSQNRFIQVGALIALRHHERYDGSGYPDGLVGEAIPLEARIVAVADVFDALLSARPYKEAWTMDAALAYLYAQRGRLFDPRCVDALLRGRAQLEQICGQFSTASARPGV
Protein: Dual oxidase maturation factor 1 (Dual oxidase activator 1) (Q8VE49)
Organism: Mus musculus (Mouse)
Function: May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- NAD
- NAD
- NADPH oxidase activator 1
Sequence:
MAALGHTLPFYTGTKPTFPMDTTLAVIITIFLTALVTFIIILPGIRGKTRLFWLLRVVTSLFIGAVILAVNFSSEWSVGHVNANTTYKAFSPKWVSVDVGLQIGLGGVNITLTGTPVQQLNETINYNEAFAWRLGRSYAEEYAKALEKGLPDPVLYLAEKFTPRSPCGLYNQYRLAGHYASAMLWVAFLCWLLANVMLSMPVLVYGGHMLLATGLFQLLALFFFSMTTSLISPCPLRLGTAVLHTHHGPAFWITLATGLLCILLGLVMAVAHRMQPHRLKAFFNQSSEDPVLEWGSEEGGLLSPHYRSIAESPETQDIPMSVASSETCFKEEHPKESDCSL
Protein: Rothein 4.1 (P86515)
Organism: Litoria rothii (Roth's tree frog) (Hyla rothii)
Function: Lacks antimicrobial activity. Does not inhibit the formation of NO by neuronal nitric oxide.
Subcellular location: Secreted {ECO:0000269|PubMed:16124032}.
Interaction partners:
Sequence:
AEILFGDVRPPWMPPPIFPEMP
Protein: Succinate dehydrogenase [ubiquinone] cytochrome b small subunit (A0A1D8PD61)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU364031}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU364031}.
Interaction partners:
- Uncharacterized protein
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- fumarate hydratase
- fumarate hydratase
- Succinate--CoA ligase subunit beta, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- 4Fe-4S ferredoxin-type domain-containing protein
Sequence:
MISTYSRIGLTTLTKSSSSSSLTTTVRPLLLANFTRGIKTIPQPPGYIVGTVNDAYVPPPPHKLEGSLHWTSERIVAIGMLPLVLAPFITGGGASTLIDSTMSALLLFHCHTGFQSCIIDYIPKRVYGSYHNYAMYLLTFGTGIAGYGIYQIETKEGGVSNIISKLWKA
Protein: Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1) (Q8JZM0)
Organism: Mus musculus (Mouse)
Function: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity).
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q8WVM0}.
Interaction partners:
- DNA-directed RNA polymerase, mitochondrial
- Transcription factor A, mitochondrial
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein bS16m
- Putative ribosome-binding factor A
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS7m
- GTPase Era, mitochondrial
Sequence:
MAASGKLGTFRLPPLPTIREIIKLFGLRAVKQLSQNFLLDLRLTDKIVRKAGSLADVYVYEVGPGPGGITRSILNANVAELLVVEKDTRFIPGLQMLSDAAPGKLRIVHGDVLTYKIEKAFPGNIRRQWEDDPPNVHIIGNLPFSVSTPLIIKWLENISLKDGPFVYGRTKMTLTFQKEVAERLVATTGSKQHSRLSIMAQYLCNVEHLFTIPGKAFVPKPKVDVGVVHLTPLIEPKIKQPFKLVEKVVQNAFQFRRKYCHRGLGMLFPEAQRLESTGRLLQLADIDPTLRPTHLSLMHFKSLCDVYRKMCDEDPQLFTYNFREELKQKKSKGQEKDGDPESCGF
Protein: Ras-related protein RABA2a (AtRABA2a) (Ras-related protein Rab11C) (AtRab11C) (O04486)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Intracellular vesicle trafficking and protein transport.
Subcellular location: Endosome membrane {ECO:0000269|PubMed:18239134}. Golgi apparatus, trans-Golgi network membrane {ECO:0000305|PubMed:18239134}; Lipid-anchor {ECO:0000305|PubMed:18239134}. Note=During cytokinesis located to the growing margins of the cell plate.
Interaction partners:
- Geranylgeranyl transferase type-2 subunit beta 1
- Rab escort protein 1
- V-type proton ATPase subunit a1
- Geranylgeranyl transferase type-2 subunit beta 2
- Golgi apparatus membrane protein-like protein ECHIDNA
- Syntaxin-61
- Kinesin-like protein KIN-14E
- Tlg2p-like protein a
- Syntaxin-43
- Vesicle-associated membrane protein 721
Sequence:
MARRPDEEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFCLESKSTIGVEFATRTLQVEGRTVKAQIWDTAGQERYRAITSAYYRGALGALLVYDVTKPTTFENVSRWLKELRDHADSNIVIMLIGNKTDLKHLRAVATEDAQSYAEKEGLSFIETSALEALNVEKAFQTILSEVYRIISKKSISSDQTTANANIKEGQTIDVAATSESNAKKPCCSSS
Protein: Coronin-2B (Q8BH44)
Organism: Mus musculus (Mouse)
Function: May play a role in the reorganization of neuronal actin structure.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
Sequence:
MTVTKMSWRPQYRSSKFRNVYGKAANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKVVFKAPIREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRLRQLQLELKNLRNNPKNC
Protein: Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP) (P53620)
Organism: Bos taurus (Bovine)
Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity).
Subcellular location: Cytoplasm, cytosol. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Predominantly located in the cis-Golgi apparatus. {ECO:0000250}.
Interaction partners:
- Coatomer subunit beta'
- Coatomer subunit zeta-1
- Coatomer subunit delta
- Coatomer subunit alpha
- Coatomer subunit epsilon
- Coatomer subunit beta
- ADP-ribosylation factor 1
- ADP-ribosylation factor 3
- Coatomer subunit zeta
- ADP-ribosylation factor GTPase-activating protein 3
Sequence:
MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDSYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHGLKSPFAYCMMIRVASRQLEDEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDANRSIATLAITTLLKTGSEGSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFSMLREEGGFEYKRAIVDCIISIIEENAESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPRTSNPSKYIRFIYNRVVLEHAEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKALNAGYILNGLAVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPLAEQRTESTPVTAAKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFTDHMVFQFDCTNTLNDQTLENVTVQMEPSEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAVACTFSCVMKFTVKDCDPTTGEADDEGYEDEYVLEDLEVTIADHIQKVMKLNFEAAWDEVGDEFQKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIVLASVG
Protein: Cytochrome P450 71D179 (Gamma-terpinene hydroxylase) (Thymol synthase) (EC 1.14.14.-) (P0DO37)
Organism: Origanum vulgare (Wild marjoram)
Function: Involved in the biosynthesis of phenolic monoterpenes natural products thymol and carvacrol which have a broad range of biological activities acting as antimicrobial compounds, insecticides, antioxidants and pharmaceutical agents. Catalyzes probably the C3-hydroxylation of gamma-terpinene to produce thymol (Ref.1).
Subcellular location: Membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MDISISWVVIIVSVLSYLILMDKWRAAKLPKNIPPGPPKLPSIGHLHLLRGGLPQHLLRGITQQYGPVAHVQLGELFSVVLSSTEAARQAMKVLDPNFADRFVDIGSRIMWYDSEDIIFSRYNDHWRQIRKICVSELLSPKNVRSLGYIRQDEMASLIRLFESSEGKPVNVSEEISKTVCTIVSRVAFGSAVKDQSLLLNLVKESLRMASGFELADLFPSSWLLNLLCFNKYRLWRMRARLDNFLDGFLEEHRVKKSGEFGGEDIIDVLYRMQKDSQMKVPITNNGIKGFIYDVFSAGTDTSAATILWALSELTRYPEKMAKAPAEVRESLKGKTSVDLTEVHELKYLRSVVKEALRLHPPFPMTPRLCVQESEVTGYTIPANTRILINVWSIGRDPLYWEDPDTFNPDRYDEVPRDIIGNDFELIPFGSGRRICPGLHFGLANIEVPLAQLLYHFDWKLPPGMTAADIDMTEKTGLSGPRKNPLILVPIIHNPTS
Protein: Brix domain-containing protein C1B9.03c (O14206)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Ribosomal RNA-processing protein 15
- Ribosome biogenesis protein erb1
- Brix domain-containing protein C4F8.04
- Ribosomal RNA-processing protein 1 homolog
- Ribosomal RNA-processing protein 14-C
- Probable rRNA-processing protein ebp2
- Pescadillo homolog
- Uncharacterized protein C4F10.09c
- Ribosome biogenesis protein nsa1
- ATP-dependent RNA helicase drs1
Sequence:
MGGIGKKRVKKRTHLKADPIQEAAIPKSMVIRSGASEVGRSLSLLTRDLRHMMEPHTAIRLKERKANKIKDYLTMAGPLGVTHLLVLSRTDNNANLRIIRAPRGPSLHFRIHEYMLNKDVRRLQKNPKSPTTEFLTPPLLVMNHFNQNSSKDSPHEALLTTTFQNMFPPISVQHTNINSVKRVLLLNRRDDGYIDLRHFIISTKPVGISRPIRHLLKGEKKDSDIPDLHNVRDISDYVLHGDGISGAASDSEIEEDATVEIDRPVPTKTEENLLSASQLLKPKQQAIKLIEIGPRMTLELIKITEDAMGGKVLYHSHVHKSKEEIKQQDNFHEQSRALKEKRKKEQDENVRRKRENKKRRKDQKKEGITSSNKNDDSGNEGSSAYSDTE
Protein: Protein RDR1 (Repressor of drug resistance protein 1) (Q08904)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcriptional repressor of multidrug resistance genes, such as PDR5. Required for growth on non-fermentable carbon sources like lactate or glycerol.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Pleiotropic ABC efflux transporter of multiple drugs
- Casein kinase I homolog 1
- Casein kinase I homolog 2
- Transcription factor PDR1
Sequence:
MASPGSTALPHKRQRVRKACVPCRERKRKCNGKSPCEMCVAYGYVCHYIDGRVPSASPQVQQVGETSPDTESRPFVLPGIHRNEQPQPINTQNVTSQNIVDPTKSRYTIQHSAVAFPRCLGLELRSTNPPRLHSFAWHCGIRPEENPNSHVLLSDLVTKEEYYRISKVYFSVVHPIFDVVNPEQLAKNVEKYWDGDVKTLEYGAVIAGVIALGSFFMGSLGHPREMDIVQYAKGILDDPTFSRIPTVEQVSAWVLRTIYLRATSRPHVAWLASCVTIHLSEAIGLHHEIDREDIAISNNVPPKRTTVVSEHTRRLFWCAWSINTILSYDYGRSSVTLNRITCKPVKETDGNFTAHLVALAHLIPQDSVNANAAQLLQALAAVHESPNAHPFLSLTKGDICLSLYRRLRLLNHILDKNVVLQIIDIGNTALSAAYALVKLDQAWWNVLSTSFQYVCVLLAIDTPESLSHVATAMKTLDNITQILGTRIAFEAQKTAKLLLEDSMKKKRQEIQQLEQATHQRSNLETTHLLDIDWDALLDPSDTLNFM
Protein: Neuromusculin, isoform I (M9PGA2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MGNMALRQSAKDVAKSNCVAVRSSISLSLVLVLCLALVDSSTAQVDTTISQQESQSVVLPCPVDAEKCGKLHSLNWFKGDDRIAAMLLGDSNVTSVNKEFDERVTVEQNPYRLVIKDLKIADEDIYLCDTTFFIPEETCDNFNGYRIELRVLVPPTEVVILDAKGDRIKNGSVVGPMQERQSLKATCTVRNTRPQPEVSWFRGTKRLTTYSPTHDLVDGLYTSTLELDWTLSREDLAQDIECRVKSAAIQNVTVTKFSVDLQVRPTSIDINGVKHHTVQGSKVVLTCDIHGARPAVNLTWYNTTTIISSGENEITEVRSKSLEKSDGTFHTQSELIFNATRFENDRVFRCEAENIVLQINREKPISSALTLEVLYPPVVKVSPSAITANTSEIVLLNCEYFANPASLTQVEWYRNDILVNVNDTTHYKGGNSENVALVIKSTEKEDIGNYSCQLSNNIGKGTSDQKINLDVQYAPTVEILMIPEGPVKESDESNVTLFCNVLDANPSVLTKVRWYANSTLLKELPDCEETREDLCHIDPSKLLLESIGRGFFYNYSCEGFNAAGWGPRSEDKELLVHYEPGPAALSHFPLVAVKKKSVTFSCSVDDPGFPESNRFRWLRGGRGPLQDIVTKDWTVEPVGLDSRTNYSCYAYNEGGKGVMATVNLEVHAPPFFIKNLPPYTGILHSSPNATLTCRIECVPRCDISWQKDGVPIERNDSRYFIKEKYMDASPATGDFESMLSVLHFNMPNWPDSKFNIEADNANYSCVSTGNIVGGSIRSRTYFGIEYAPENTTVSENIVYVQEDTIPGRVICKSRANPEPSYKWIFKNETIANGNALIINTAMNRNDDGTYTCLAYNKHGSSIAKTVIKVQFKPRCEIERQEIDDQDTLICTAYGNPIEADFSWSIKTENETDENLGSGKKENSVEKSFYILQTDYAISRTYRCVANNTVGYGPFCEIEVAEQLAWWQLWEKNTLIILVAAILGLLLTVIVICCIIICICRRRRRQDKLHDKSSSLREPLTEPGEYENLPFHGLQTAPNKFSTTPTNFNNNTNAVRVAQRPKELIGNINQPSVGLYQDCQATHDPLLYHQKYFCDQDALNDQRSQYTTMHRPPNNVQYNQSLFKPDSNLQDQHNLSNCISKSYTEYYQQHQRSEKLQMIFPQGASKELNSNSLCNTDHTPHSALVNINLRKYDRTEEELLGNMPRARHRKGTLNVENKFYSLKHLGGIEVRNQDLDKDYPIGGTTSSTPSATDDSSLSKCKIHNSLGCNRLCNVGTNVQPMRVYDPPGYQNMVLERADDQITLSKKDECNLATVQTHTHPGKDKIKNHHHWIHQHREKKDEGLGSDFHQLEPERISIYRSDSGISNSSYESQFSKPKMATLNSSSGPLVRKYAHRNIKVHNNVFNTSNVTESEAQLDDSSTLHQSCTVQSFAPSHCNRPQPRNRYSEETTKNECEQHQLGHQSLRPASTPSECISLDTSSRSEYIMSTVPAQSDSVETPNEKIQMLAINPLLVKNWNNESYTGNKINKKQRRQTINNPYEHIQSHPYARPGDVCEVSRKAQSNSSEAFKTYNYGSKSNSSAPQTAAPEHSKVKNATKICKKNGIGANREHYEGMLASKHIQGSRLGSLADIDDFPSQGPLNALVGNPADCLVARRPIRLPLRKHHTFHFQSTQTANGKLQQLRERLQLQLHESRKVDQEKFPLVFDALELSEKHAFKPISPIPSLNNSAVQSTGEQKQVDFPKHGSVRHLKGAEDDEDLGYSFCEEECVVENDINPTSDNLKTAPTNSSCSSTAVESANPINAQIFDDEFIYADLESQHYGPINYKAASLYSQVKKNKESGALDDLK
Protein: Unconventional myosin-XIX (Myosin head domain-containing protein 1) (Q5SV80)
Organism: Mus musculus (Mouse)
Function: Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments. Required for mitochondrial inheritance during mitosis (By similarity). May be involved in mitochondrial transport or positioning (By similarity).
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q96H55}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96H55}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q96H55}.
Interaction partners:
- Mitochondrial Rho GTPase 1
- Mitochondrial Rho GTPase 2
- Trafficking protein, kinesin binding 2
- Trafficking kinesin-binding protein 1
Sequence:
MLQQVNGHSLGSDAEGRASLKGDLREFLGGEIPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHVPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCENHKIAERIEQRILNSNPVMEAFGNACTLRNSNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGATKDERLQWHLPEGTAFSWLPNPESSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEALPCQVMDDTKVSVRTSALLLQLPEKMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADSKSWTAFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSREPSFVVVHFAGPVRYHTAGLVEKNKDPVPPELTELLQQSQDPLLTMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHNTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFIERYKLLRRLGPRMSSGLGGLEPAEGSSEQPLCAKEATLQPLLQDILHALPALIQTAATPSDPAKNTQIPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVLIQAAFRSWLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKPMPQAPGTLRSSMSPAHTRFLGAIIHLWPLGLVLANSADGVRGFQRKLVAHACLRLPSDRPSNKVQTPQQDQAGITSIRALPQGSIKFHCRKSPLQYADICPDPSASCVTGFNQILLESHRPVQV
Protein: Protein root UVB sensitive/RUS domain-containing protein (Q381S4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MYRHSVHTYTLFFPCALTLTGLMMRLVACSLCGTVRRHASNHYVGPTLLRIRHMAPLNGGIRSNRSRAVASCVTDTSFPCEPQSQRIVISPRDGTKGGYSSHASVVTSYNHSNKQKREVSLTPSELGFSQCNVNYSWETVVAHPLEVRLASRRNESLLQRLHLFGMPAGYPDSCGEGFRRYFLLSLCSSFVSSFASSIGYQSILNGFLLASSPQLWMLKDLAPALAAAYLANRVISYENRPKFWFVFSVALHNLSVIAEMIIPTTVPNHLLAAAILTSCVRQSASLMFLVTRASALQHFAISNNLAELTKKFNSFGMVIYTVSTALGIAYTSLVPSVTAQLATVLMCCGANLAISHLSMCNIAFRILNETTLSVILRFYMREEGHQRGRVLSPREVSDAIGLRMIDRGRSDGNDRIGLLYVNPPIGKIRIRYSSLDEDVVYLCSSEMFLFALWEPSAPLSLLDRWHRWEKPQLTQRISKWFFSKKKNVPTSEVLGKRLVLFVHQECDSLHLLTAYLLAYTALLQHADDLAELRRFLRSCNGEQSLWLKRGGELRKSLQAVGWDVEQLSLDPLNFRLSSLSFAAQPRCMRHLNPLN
Protein: Protein aurora borealis (HsBora) (Q6PGQ7)
Organism: Homo sapiens (Human)
Function: Required for the activation of AURKA at the onset of mitosis.
Interaction partners:
- Serine/threonine-protein kinase PLK1
- Aurora kinase A
- Cyclin-dependent kinase 1
- LIM domain-containing protein ajuba
- G2/mitotic-specific cyclin-B1
- Serine/threonine-protein kinase PLK4
- F-box/WD repeat-containing protein 1A
- Protein ECT2
- Rac GTPase-activating protein 1
- HAUS augmin-like complex subunit 6
Sequence:
MGDVKESKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGKFRWSIDQLAVINPVEIDPEDIHRQALYLSHSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSQCHSSKCTNINSDSPVGKKLTIHSEKSDAACQTLLSLPVDFNLENILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPSASPGSPHSGVQTSLEMFYSIDLSPVKCRSPLQTPSSGQFSSSPIQASAKKYSLGSITSPSPISSPTFSPIEFQIGETPLSEQRKFTVHSPDASSGTNSNGITNPCIRSPYIDGCSPIKNWSPMRLQMYSGGTQYRTSVIQIPFTLETQGEDEEDKENIPSTDVSSPAMDAAGIHLRQFSNEASTHGTHLVVTAMSVTQNQSSASEKELALLQDVEREKDNNTVDMVDPIEIADETTWIKEPVDNGSLPMTDFVSGIAFSIENSHMCMSPLAESSVIPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTCEVESKSQAFNMKQDHTTQRCWMKTASPFQCSSP
Protein: Choline/ethanolaminephosphotransferase 1 (mCEPT1) (EC 2.7.8.1) (EC 2.7.8.2) (1-alkenyl-2-acylglycerol choline phosphotransferase) (EC 2.7.8.22) (Q8BGS7)
Organism: Mus musculus (Mouse)
Function: Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Y6K0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Y6K0}. Nucleus membrane {ECO:0000250|UniProtKB:Q9Y6K0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Y6K0}.
Interaction partners:
- Phosphatidylethanolamine N-methyltransferase
- Choline-phosphate cytidylyltransferase A
- Ethanolamine-phosphate cytidylyltransferase
- Choline-phosphate cytidylyltransferase B
- Phosphatidylserine decarboxylase proenzyme, mitochondrial
- Phosphatidylserine synthase 2
- Phosphatidylserine synthase 1
- Lysophosphatidylcholine acyltransferase 2
- Lysophospholipid acyltransferase 5
- Lysophosphatidylcholine acyltransferase 1
Sequence:
MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKLLPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALIFSFFDLIRYCVSVCNQIASHLHIHVFRIKASTAHSNHH