wanglab/gogpt-training-data huggingface dataset:
Protein: Small ribosomal subunit protein uS4B (40S ribosomal protein S9-B) (RP21) (S13) (YP28) (YS11) (P05755)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uS4 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22096102}. Nucleus, nucleolus {ECO:0000269|PubMed:15590835}.
Interaction partners:
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein eS12
- Small ribosomal subunit protein uS13A
- Small ribosomal subunit protein uS12A
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS9A
- U3 small nucleolar RNA-associated protein 22
- Small ribosomal subunit protein eS24A
- Small ribosomal subunit protein eS4A
Sequence:
MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKREIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAAEEAEDEE
Protein: Hexosyltransferase (EC 2.4.1.-) (Q580Q5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}.
Interaction partners:
Sequence:
MFVPSNVAAVWKAQRFLAVLGIPSVDNSERSRRRDLQRQTCWKYSGVATRSNNFSGSLLPLYLLAPHQSNSYLISHSLKEEAARTHDIITLPTNDVSPSTRKKIGENGNWGIEAEVAMSRKTYLWLRFALHMFPNVSYIVKGDDDIFIRVPKYLADLRVMPRHGLYMGRYNYYNRIWRRNQLTYVNGYCITLSRDTAQAIISYKPLERLVNMPFSMWDYFDFLDLGMFYEDVMVGMILREKVVYRNLISVEMGRCHFHNAGKFGVKKSVRNMSVVIHHIQEADYEMLMDYFPEGVIPPAPSKLMWLNSNWAAMQCEFRLGRKREILPSFPFWRKRA
Protein: Uncharacterized protein YgaM (P0ADQ7)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein YqjD
- Protein ElaB
- DNA protection during starvation protein
- Osmotically-inducible putative lipoprotein OsmE
- Serine/threonine kinase YeaG
- Uncharacterized HTH-type transcriptional regulator YiaG
- Uncharacterized lipoprotein YbaY
- Potassium binding protein Kbp
- Uncharacterized protein YdiZ
- UPF0337 protein YjbJ
Sequence:
MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAEAARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGALLSMRKS
Protein: Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18) (Q15543)
Organism: Homo sapiens (Human)
Function: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF13, together with TAF11 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes.
Subcellular location: Nucleus {ECO:0000269|PubMed:9695952}.
Interaction partners:
- Transcription initiation factor TFIID subunit 7
- Transcription initiation factor TFIID subunit 3
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 4
Sequence:
MADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLVIEFITEMTHKAMSIGRQGRVQVEDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEANYGS
Protein: N-alpha-acetyltransferase 20 (EC 2.3.1.254) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB catalytic subunit) (A8MZB2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLSQSCNLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
Protein: Two-component response regulator ORR22 (OsRRB4) (Q5SML5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional activator that binds specific DNA sequence. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. May directly activate some type-A response regulators in response to cytokinins (By similarity). Functions as a response regulator in response to cytokinins.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:22383541}.
Interaction partners:
- Histidine-containing phosphotransfer protein 2
- Pseudo histidine-containing phosphotransfer protein 2
- Pseudo histidine-containing phosphotransfer protein 5
Sequence:
MLLGALRMEERKGLMGRERDQFPVGMRVLAVDDDPVCLKVLETLLRRCQYHVTSTNQAITALKLLRENRDMFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSVNGETKTVMKGITHGACDYLLKPVRIEELRNIWQHVVRRKFGNRERNNLDFSKECNKPQSADTDHGPYQPTCGSSDQNGRSSRKRKELHGEDDDEGDDNDYQENDEPSAAKKPRVVWSVELHRKFVAAVNQLGIDKAVPKRILELMNVEKLTRENVASHLQKYRLYLKRLGAVASQQASIVAAFGGRDPSFLHIGAFEGLQSYQPFAPSAALPSFNPHGLLTRTSAAAAFGLQELAAPSSTIQTSTGNVTVGHCLEENQQANLAQGLTAAIGQPQLQQNWIHQEGNGLSDVFSGSSLTNTLSSTLQRVPSSSLPPQELLECKQAKVSMPPSIRIPPSSSALLERTLGVSTNLGDSSISQQGALPIDGGFSADRLPLHSSFDGAVATKLDTSLAASQREIGQQGKFSVSMLVSPSDNLALAKNAKTGASSSGSTIILPLDTARHSDYLQFGGASNSLQKMDGQKQDHIQSSNIIWSSMPSTQLPSDTQIHNTQNQRLDSGSFNHNIGAHLADQTNASASILPQMKFDTRISEEKMKQKNTYDLGSSKLQGGFNSSGCNFDGLLNSIIKVEKDDLPFMDNELGCDLFPLGACI
Protein: SSD domain-containing protein (Q21883)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MTGASALDPPAFVRLLNRLFRQCGLFVADNDKAVLIVTLLLTAFCSSKICFTKQEDDIKTGYTPVGARSLDEIEVFSDFFASTGDPIAVFLFITAKDNSSMADYNTMKEVVDIMDYVGSNLTHKGESFYTLCTDFCQINEPVRQYYNGLAMKQQNLSEVGSRFQLTFPMMQVLGKELDLSPNFFGVKTDEDGNVEYVKIIMLQIRANIPNDWKKEDAAEYERMISQYFHFKYDSTHVTPLAMSLTYTGDEVVRTGLTIFPFIGVGFIIMTTFSIITIYYSSSRLDQWSVHKVSEAILACVCPLLATSSALGTLFWFGFRFGTILCVTPFLILAIGVDDAYLQVHACMRLTAEDSSMTKREKIARMLVEVGPSIAITSMTNLFAFLVGIYTPTPEISLFCAGNAVAILFDFIYQITMYTAILSICENLEMRKNATKRKDSGLSFKNEQFTVMLDSYCDWVANAYTHLLVLFCFIVYIFVSIRGALNINIILSPDKLVIGDSPLLQVNYLRDQFVLPNYTTVNIFVQNPGNLTIQSNLDYMNSLFDSFESYPECLGKKFSHYFVRDYESFRESSLEEMEMMEDEEGDTNKTALEPFSKAAMSEFLAWPEFQHWNGFVKFDKNGMLSKYWATVSYHGEGLGDFQVRRRMLNRWRATADQFAPLNVSIFDDYAPFVDTLETILPATISTSVCTLICMMIVCFLFMYNVFTVFVATLAITSICIGVFGFLSMWGIDLDPISMACLIMSIGFSVDFPAHITFHYFREGLHDPQSTPAKRVARSLAAIGFPLLQCGLSTILFVLCLLFVPTYMGEVFVKTMILVVTLGLIHGLFIVPAFLCAFTAIHQTCFSSSRVAHSQSFSSLAKLFSWRISPSTSDNKISA
Protein: Calumenin (Crocalbin) (IEF SSP 9302) (O43852)
Organism: Homo sapiens (Human)
Function: Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:10222138}. Golgi apparatus {ECO:0000269|PubMed:10222138}. Secreted {ECO:0000305}. Melanosome {ECO:0000269|PubMed:12643545}. Sarcoplasmic reticulum lumen {ECO:0000305}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000269|PubMed:12643545}.
Interaction partners:
- Calreticulin
- Protein disulfide-isomerase
- Endoplasmic reticulum chaperone BiP
- Aurora kinase A
- Vitamin K epoxide reductase complex subunit 1
- Extracellular serine/threonine protein kinase FAM20C
- Endoplasmin
- Protein disulfide-isomerase A3
- Translocation protein SEC63 homolog
- Vitamin K-dependent gamma-carboxylase
Sequence:
MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
Protein: Dynein axonemal assembly factor 4 (Q6AZN0)
Organism: Xenopus laevis (African clawed frog)
Function: Axonemal dynein assembly factor required for ciliary motility.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8WXU2}. Cytoplasm {ECO:0000250|UniProtKB:Q5VJS5}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q5VJS5}. Dynein axonemal particle {ECO:0000269|PubMed:30561330}.
Interaction partners:
Sequence:
MPIIANDYTWEQSENDVYISVPLKGTKASASNVLCSESYLKVNFPPFLFEAFLFAPIDDSTSSAKIGNGVILFNLHKKEPAVWDALTLAHMEKEEMQKIRENAVAKEQEKAQEETKAKAERKRENEKYSLEVTMKIDEVERKRIEDVKEEERKKATEELEKWKEKQRIQKLNEMIQKKQIRQENERNKALHTGSLKHCSTATTVQNDRTINVKQKEKILPPTRSTGCIQIQFTPRVFPTALRESRVAEEEEWLHKQAEARRATNTVDLGLEDLTEEEKNPEWLKDKGNKLFAAGDYLAAVNALNLAIRLNNKIPGLYLNRSACHLKLRNLHKTIEDSSKALELLTPPVPGNASARIKAHVRRGTAFCELELYVEGLQDYEAALKIDPTNQNMKSDAEKIRRVIQSSLPDIERGIMLDIKDL
Protein: Uncharacterized protein (Q386K2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Uncharacterized protein
Sequence:
MEEREEGEVRRESFNAPEATTMSKHGSLKDAMRQVLETKGVIDHVKAELRAAIFHSLQESNSQGDDIESARPPIPPENLLLNELIKDYMAFNGMEHSLSVFKAESGAGKEATSAIMPRAILASQLGLTGAPASVPLLYAMLHELRICSENS
Protein: Phosphate transporter PHO1 homolog 4 (Protein PHO1 homolog 4) (AtPHO1;H4) (Q6R8G6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May transport inorganic phosphate (Pi).
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable WRKY transcription factor 10
- Receptor-like protein kinase HAIKU2
- Protein HAIKU1
- WRKY transcription factor 44
- Leucine-rich repeat receptor protein kinase EMS1
- Auxin response factor 2
- Agamous-like MADS-box protein AGL61
- Cytochrome P450 78A5
- Agamous-like MADS-box protein AGL62
- Probable E3 ubiquitin-protein ligase RHB1A
Sequence:
MRFGKEFVSQMIPEWQEAYIDYAYLKTILQDIQASRNRSDSNNQSSTPSFARNLTRRYNRDALVSENHDIVVNTVTRLEEGLETAAYETTFLKAGEAGGDFEVTFFRTLDREFNKVNNFYRLKVETARTEALALNKQMDALIAFRHKVMDQNQKNPSVFDSVSEDINGSASEVGSSSKCTEHNVALADLMRNEDTSNESILERIRMNKTREITPLSAIKTILKVHKQDELKFTRDNLKEVEKRLQVAFIEFYQKLRHLKNYSFLNASAVSKIMKKYDKIAKRNAAKLYMEMVDKSFLSSSEEVHKLLLKVESIFIEHFSNSNRREGMSHLRPKINKERHLITFSTGFFFGCGISLIVALGLIIHARNIMGTPGQRTYMETMFPLYRFFGFVVLHMDVYAANIYFWRRYRVNYSFIFGFKQGTELGYRHVLLLSFGLGTLSLCAVLLNLDMEMDAQTKDYRLVTELIPLFLLVLVIIIVLCPFNILYRSSRFFFLSVLFRCIAAPFYAVHLPDFFLGDQLTSQVQALRSLEFYICYYGFGDFRYRRRNTCTSNIGFRTFYFIVAVIPYWLRFLQCIRRMVEDRDLSHGYNGIKYLLTIVAASLRTAYTLNRGSNWNITAWVFSGVATFYGTYWDIVLDWGLLQRGCKNSFLRDKLLVPHKTVYYAAMVLNVLLRLVWLQTVLDLKFSFLHRETMVALMACLEIIRRGIWNFFRLENEHLNNVGRYRAFKTVPLPFNYEEDGDHHNN
Protein: Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (Malate dehydrogenase [quinone] cytochrome b560 subunit) (QPs-1) (QPs1) (Succinate dehydrogenase complex subunit C) (Succinate-ubiquinone oxidoreductase cytochrome B large subunit) (CYBL) (Q99643)
Organism: Homo sapiens (Human)
Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:37098072}; Multi-pass membrane protein {ECO:0000269|PubMed:37098072}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Succinate dehydrogenase assembly factor 2, mitochondrial
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Fumarate hydratase, mitochondrial
- Succinate dehydrogenase assembly factor 2
- Succinate--CoA ligase subunit beta, mitochondrial
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
Sequence:
MAALLLRHVGRHCLRAHFSPQLCIRNAVPLGTTAKEEMERFWNKNIGSNRPLSPHITIYSWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSGVVVLVLTVLSSMGLAAM
Protein: Catenin beta like 1 (A2A2P1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRRKQTGTRERGRYREEEMTVVEEADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQV
Protein: Multifunctional fusion protein [Includes: Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (L-glutamate gamma-semialdehyde dehydrogenase); L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88)] (Q5AK46)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Proline dehydrogenase
- Pyrroline-5-carboxylate reductase
- glutamate-5-semialdehyde dehydrogenase
- Ornithine aminotransferase
- NAD-specific glutamate dehydrogenase
- Glutamate 5-kinase
- Transaminase A
- Aspartate aminotransferase
- Glutamate dehydrogenase
- Put3p
Sequence:
MLRSTTRNTLRLATRYTKVSSSIIRHTLPTMFGSSTGGSGIRFASQLAHVKTPPNLQNEPVKNFSFKDTKDWDLLRASITKFTDEGALKVPLVVGGKKIYRDEIKTQVNPAKHSQVLADVSQATPEDIIAAIDAAKAAKAKWATTSWTDRAAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCVAELIDFFKFNVKYAEEMYQQQPIQTSPGVWNRAEYRPLEGFVYAVTPFNFTAIAANLVGAPALMGNTVVWKPSATAALSNYLLLTILEEAGLPAGVINFIPGDPVEVTDIVLNDKEFSALHFTGSTDVFKSLYSKISNNVAADKYRDFPRIVGETGGKNFHLIHPSASINHSVLSTLRGAFEYQGQKCSATSRLYVPESIWPEFKDQLVGAMSQITIGNSSEPENLNTFMGPVIHEQSFKKLSDAIEQAKSDPELEIVTGGSYDNTKGFYVQPTLIKTTNPNHEFLTKEFFGPILTTYVYPDGEFENIIKSIDSITKYGLTGSIFARDRDAVRTAEENLRYAAGNFYINDKSTGAVVGQQWFGGARASGTNDKAGSGNILSRFVSIRNIKENFYELTDFKYPSNYQ
Protein: Uncharacterized protein C11E3.14 (O13693)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MFNIKNHLRLPIIGKREPEEQPDPIDHDLHVQRLRELLYGLDLMLDDDAQGVKSAFSDDTVESAVGRSGSAFYNAILGLEPKAIEEATEALYHAEQVTEERKKHFEHHDRPIGSYPAGMELQLCLSDIYLMQSALGFVSDSIVDSMKAAYRIRKTFLSFSKMMEHVRDVQHKKETGEIKSLSPNATFIDEFIESGVITGYGVLTFLVSMFPPSLSRILSLFSFHGVRKESLELLWRASKYPNIQGAIALLCLYAFNAMIQSLGSIPPSNYDQELEHCLQAVKDIRKRYSKGALWAVMEAKIYFLTGESQMALEMEELSIDSSMEQIIAMKGFDTAMLYVGMRKFKQAADAIIELEDLNSWSHAFYRYFAGCCLLQHGKEILGSGGSEEEAKASIDHGIEYLKNAPTLVQKKKKRRTLPVEAYLIRKVQKWEDRAEKLNISIADAMDVPPYAELIYIFVICSLKDPKEAEALRADLETCKCSEEDEAGLKEFLLGVIDRHLKEYDSCRVRMEHVLQLDQGYLSRDNRELWILPFAYYELAALYWDMHGMAAEKEVNHYLKKAQEFNDYDLQNRLSMLAQAATQTLQSEK
Protein: Uncharacterized GTP-binding protein C9.07c (Q9UT21)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- mRNA export protein 33
- RWD domain-containing protein C1393.09c
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS15
- DNA polymerase epsilon subunit B
- Large ribosomal subunit protein uL23B
- Syntaxin-like protein psy1
- Probable citrate synthase, mitochondrial
Sequence:
MATTAQKIKEVEDEMAKTQKNKATAKHLGMLKAKLAKLKRELITPTGGGGGGGLGFDVARTGIGTVGFIGFPSVGKSTLMTQLTGTRSEAAAYEFTTLTTVPGVLQYNGAKIQILDLPGIIEGAKDGRGRGKQVITVARTCNLIFIVLDVLKPMSHKRIIEEELEGFGIRLNKEPPNIVFKKKERGGINITNTVPLTHIDLDEIRAVCSEYRVNSADIAFRCDATIDDLIDVLEGNRVYIPALYVLNKIDSISIEELDLIDRIPNAVPICGNRGWNIDELKETMWDYLNLVRVYTRPRGLEPDYSEPVILRTGHSTVEDFCNNIHSSIKSQFKHAYVWGKSVPYPGMRVGLSHVLLDEDVVTIVKK
Protein: Magnetosome protein MamX (Magnetochrome MamX) (V6F2C2)
Organism: Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)
Function: Required for correct biomineralization of the magnetosome, maybe via redox control. May function with MamY, MamZ amd Mms6 in biomineralization (Probable).
Subcellular location: Magnetosome membrane {ECO:0000305|PubMed:30367002}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Magnetosome protein MamZ
- FtsZ-like protein
- Liposome tubulation protein MamY
- Magnetosome protein MamH
- Magnetosome protein MamT
- Multi-heme protein MamP
- Magnetite biomineralization protein Mms6
- Magnetosome protein MamB
- Probable membrane transporter protein MamO
Sequence:
MNTKAVAHPDIAVWIMALGIAFSMALVLTALFNANPWEDHTYDLAPPIVAGMAAPHRDGREKMVCSSCHIVTPASAATGPGAGTLPIVEGTPAPHVDGREKMACASCHTIVKKGSVAKSGKASPAPVAFSQGMPLPEAMSVALAVTPAPAPLGNEAHERMVPFRYQGKIVSVAGAGTRSVWGDIYIQINDGINPPMWIDLAPLWFLQAEGCLVRPGMFVKGTAFRDPTQASAGLDYAMSVMANGEVCALRDDHLNGLWANVGGVDAEER
Protein: SWI5-dependent HO expression protein 2 (P36068)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruits the MYO4-SHE3 complex to the ASH1 mRNA. Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12499354, ECO:0000269|PubMed:14561888, ECO:0000269|PubMed:18566598}. Nucleus {ECO:0000269|PubMed:12499354, ECO:0000269|PubMed:14561888, ECO:0000269|PubMed:18566598, ECO:0000269|PubMed:19244342}. Note=Shuttles between the nucleus and cytoplasm and is exported in an mRNA-dependent manner (PubMed:12499354, PubMed:14561888, PubMed:18566598). The presence in the nucleus is essential for PUF6 and LOC1 to bind the ASH1 mRNA. {ECO:0000269|PubMed:12499354, ECO:0000269|PubMed:14561888, ECO:0000269|PubMed:19244342}.
Interaction partners:
- Myosin-4
- SWI5-dependent HO expression protein 3
- Transcriptional regulatory protein ASH1
- 60S ribosomal subunit assembly/export protein LOC1
- Heterogeneous nuclear rnp K-like protein 2
- Pumilio homology domain family member 6
- Increased sodium tolerance protein 2
- Myosin-2
- Protein SCP160
- Actin
Sequence:
MSKDKDIKVTPGTCELVEQILALLSRYLSSYIHVLNKFISHLRRVATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASMFVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIESLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSILDGKLSALDEEFDVVATKWHDKFGKLKN
Protein: Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1) (O42661)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:24298023}. Cytoplasm {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:24298023}. Note=Localizes to the nucleus predominantly. {ECO:0000269|PubMed:24298023}.
Interaction partners:
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein-associated protein B
- Pre-mRNA-splicing factor cwf2
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-splicing factor prp1
- U1 small nuclear ribonucleoprotein 70 kDa homolog
Sequence:
MKLVRFLMKLTNETVSIELKNGTIVHGTITSVDMQMNTHLKAVKMTVKGREPVPVETLSIRGNNIRYYILPDSLPLDTLLIDDSTKPKQKKKEVVRGRGRGRGRGTRGRGRGASRGF
Protein: High mobility group protein HMGI-C (High mobility group AT-hook protein 2) (P52926)
Organism: Homo sapiens (Human)
Function: Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED
Protein: Ank3 protein (Q3T1J5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MALPHSEDAITGDTDKYLGPQDLKELGDDSLPAEGYVGFSLGARSASSDRSYTLNRSSYARDSMMIEELLVPSKEQHLPFTREFDSDSLRHYSWAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLSELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKVRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKAEKADRRQSFTSLALRPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETPSGSLESPAQARRITGGLLDRLDDSSDQVRDPITSYLTGEAGKFEANGNHAEVIPEAKAKAYFPESQNDIGKQSIKENLKPKTHGCGRAEEPVSPLTAYQKSLEETSKLVIEDAPKPCVPVGMKKMTRTPADGKARLNLQEEEGSARSEPKQGEGYKVKTKKEIRNVEKKAH
Protein: MADS-box transcription factor 4 (OsMADS4) (Q40703)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor involved in the development of floral organs. B-class protein required for normal development of lodicules and stamens (whorls 2 and 3). May function as a heterodimer with MADS16.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MGRGKIEIKRIENSTNRQVTFSKRRAGILKKAREIGVLCDAEVGVVIFSSAGKLSDYCTPKTTSVFPPLSRILEKYQTNSGKILWDEKHKSLSAEIDRVKKENDNMQIELRHMKGEDLNSLQPKELIAIEEALNNGQANLRDKMMDHWRMHKRNEKMLEDEHKMLAFRVHQQEVELSGGIRELELGYHHDDRDFAASMPFTFRVQPSHPNLQQEK
Protein: Nucleoside transporter 4 (Q8I2A8)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MLKKSEEIQIKVIFFFIGLLLSLPSHILINVSFLINHIYKEEIAITVMGFLSGFMIISSFLQLTFEFTSFKWIMICNGLNVFNLLLLLIFVCVMKCSKYYIYGISGIIGFFIGYLYSSCTKYSLLFPLKVNGYMVTGISFSSLFFFAINLIMSYFSIEDGNISSYYNTIYLSIGTIVFIEFIILVCIIFIQYNSPYFKEQKEKIESAQNKKCIEYNGSNDLCEVEKGKNKSSENIQSNNVSMISKCKNKIKNVGKMFNCANIIEGACLIRYYYLCLIPIFFSFFVTSIIYPHMIPNKLKKNVYYKYLFMFLYQLSDLIFHIIVTVYYSAFNFFKQKYVAILCLSRILLLLLSFKIKNLTEASFLYSNTFLSFLIFVIGGTNGSLINISYARISDCFEESNKKTKQIAVASSFCALCLLMSFALAPWFCNAIIHL