wanglab/gogpt-training-data huggingface dataset:
Protein: Zormin, isoform K (Q0E8J5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MERRQALDSSMSSLYSVASSSNPNPRQPHTGHQLQTQQSQQSQQSQLDAFNYSATMSSSSPTPSQAMSTAMSTGTGTGTGTTHTTPPSSSSLRATTIGTVVVRCGPIQLVIALLQSPEKIYIKVVELEPKITALGENLDESLRMQREHDETLRNLQSLPGPMDEFVQKADKLLASKRISSELVNAMADTLNIIWQDILNLLQDRQHLLILCTQFHDKMTQCFRKMDQLELACEETLHPPDVPRVQEFLNRFKQLRIDMLTGVMAALKDGNELLAQLEELEKLETLDTRPEHIKRDATRAVHQVQQWLEALHDRRNSLELAWQTRKIQMEQCLALALLGRELVDLEAALQQARMELNTMYSLGECEHTANEMLTKYREWKQQALLLRDRALKITRAKEKVQSAGHFTEEDACARAYAVLSGCTEHLDLVDQREHWLHQSREFFAKAEHTVSVLEKLELELTSVKLPPHSPESYAMFSKVDRDVRNFTEEPLRLGYGILDEVGRTQPETQGVKRVLDELENRKVYIQGICANSSEDQQKVQRALSEFLNHHNELLAWLRASGQHQLQQSVDMGGNLQQAKQFLLQHHELMQDLEIKGELINLLLESIKVHLESLSPQERYDVDSKAESLHKHWIELKDLVLKRVDYVSLLIDFFELANELSSQLDNLQRQLQQTPDEHKLQFLQATWTGIASTFGELKSRGQRFINLKIVDPYLETKSSAQAVQETLNDFSKRQVDVTSSLENWTTSIAEKREVEYLLEKVMSDNEETVAKSTQVDTQLYPVFTSQSVDSKQLLISTREKLTNVIQDIERAQDEIQQRIQTTLGIQTKDQPSLAKIEQVINNLRMLKAKLDGIKYDYRTLVESVIQFLENIVQLRREIDDYFARQQKEPASGADRSIAEHEKFRDQCMDKFRSLITQSELLIDRVRVLEPPGAREIDTDRILKLLENLRLHFESNSSARMSTLERLEKIEQFRSDLEDIDRSLDSVSQQLHEINNQSVDSLAAAKTTSLAFEYFERTIECSMPRQLKSTRHQRRWGQTAHTIELLEKRIEKFTESTSQQLFITNPESERYVKDELRKLNEKWQSFKDQVKQKRKSLNQATDFFEVVEKIDAEYREISYFYTSVSNKVPYLRDSVEAGNLVNDIENYVTSREAALRSKLDSASQCAHDMNKVSSLYNDVMNIFQSFIKLKMDINVVQERLKQEQRQKEQRERDARDQAEREKAIKEAEAKERLHREEQSRLENQRQQAAIEQAQRELAARELALREQAVREEEARLQAIREQATREQLAREQAAREEELRIQSLRDIARREEEVRLQNIRDEETRIRREEEERIRRENESRSKREEEARIQREEITRLQTLRDQVDQQRIVTENIRKDIQVNSIFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQAERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITTQSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFLVSTSGERQVLTIQKLTHDAVGKISCVAENEAGKATCVAFLNIRGSGLPASSDVQTVSQEHNTESSRVTIKKQTFTTTSTSQVNSYEGNAPQTEVHHSSAHIDQSLKQLGQQRPEIVESHHYQELHKSKEMSSPTVQQKSFSFIQSSGANGQSAVAIPDSPTRLRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKSIADCAILEPSPERLQEVVKTIVYETGPVAPASEFKTEGYKYTSSSMTSNYSHNMQSSSSSSHHETKFSSTSAPPPVVTYPSPIPAQRKTPAAEFSDYSSEIDERFRSVSRANESDAEIKGYRVVFPPTPTPRTNIATNGHKSPVVVITPSPMEFEPTPQDYARPKFEPISKEIRHEIKTETSSKQSKFMQNQQQNQPVFKPKPVAAKFIAATQQQQQKQPQATSRPTMYYNAVAGAPMHVAKVATETKNVMQMHESTESSQRVVNMQQTKRIIHFDSPQEQRDQQILEPFPYSPATSRTPSRQSHLPPPATPTKFVPGEFRESDYESEIDGARIQPLWSPYGDGMTKGFRRVAPPQGAGRSCSLPRTYERVLSPMEFDRGPEMPSKIHVDINTLRKEQRGGSTVTTQNRTQSLNRNTTMRQQQQQQQQQSMDQIDRAGTLPRYGYSSLQQQAENQGRRMGSTFLQKSHQFVDDVSREIRSSASNGIRPGFKRAPSEGSSQQPQAFRDESRVSQYDQGTQTDSLLITEEEPAPEATDQPLGNGVNKTPLRKSASFSSTSTSSPASSSMGSATSTMSLRSSTPLRSHNHSQSSRALRSDTINTFQKWETTIESISYVSTKTVSISDFTQEPQLREQTVN
Protein: Uncharacterized protein (Q381N5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase
- 50S ribosomal protein L13, putative
- Uncharacterized protein
- Tetratricopeptide repeat
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein bL21m
- Ribosomal protein L30 ferredoxin-like fold domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MRPTFPALGSRAKGYENRVMVYAHRRHRAWYLPPKLAHARSPLANKSPDEYGNTWDPRTGVEWYHRLRRRGAYRHWPWARWNDDPVRQHQELSCRRTFSAAVTGANEGVPLWNYYAEVGQEYGLPSHFPLSFMAPFIHQYTSRAWSRKEIERHLKVVEERTGLRTIQQACDATSELLEWGEEEMGVVPHGLLQHVVMLAEDIVLQNKKKAYRKAAHERGILRTTTMERYYALPHLRTGPPMPTTLEQPSGEFPWGKFSTMVGGTRIHPLYRPDGFFKDNMYPA
Protein: Venom prothrombin activator trocarin-D (vPA) (EC 3.4.21.6) (Venom coagulation factor Xa-like protease) [Cleaved into: Trocarin-D light chain; Trocarin-D heavy chain] (P81428)
Organism: Tropidechis carinatus (Australian rough-scaled snake)
Function: Snake prothrombin activator that attacks the hemostatic system of prey. This protein is functionally similar to blood coagulation factor Xa. Induces cyanosis and death in mice at 1 mg/kg body weight during blood clotting.
Subcellular location: Secreted {ECO:0000269|PubMed:10397729, ECO:0000269|PubMed:12871464}.
Interaction partners:
Sequence:
MAPQLLLCLILTFLWSLPEAESNVFLKSKVANRFLQRTKRSNSLFEEIRPGNIERECIEEKCSKEEAREVFEDNEKTETFWNVYVDGDQCSSNPCHYRGTCKDGIGSYTCTCLPNYEGKNCEKVLYQSCRVDNGNCWHFCKRVQSETQCSCAESYRLGVDGHSCVAEGDFSCGRNIKARNKREASLPDFVQSQKATLLKKSDNPSPDIRIVNGMDCKLGECPWQAVLINEKGEVFCGGTILSPIHVLTAAHCINQTKSVSVIVGEIDISRKETRRLLSVDKIYVHTKFVPPNYYYVHQNFDRVAYDYDIAIIRMKTPIQFSENVVPACLPTADFANEVLMKQDSGIVSGFGRIQFKQPTSNTLKVITVPYVDRHTCMLSSDFRITQNMFCAGYDTLPQDACQGDSGGPHITAYRDTHFITGIISWGEGCARKGKYGVYTKVSKFIPWIKKIMSLK
Protein: LD31322p (Q9VUR2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- Nucleolar protein 14 homolog
- U3 small nucleolar ribonucleoprotein protein MPP10
- KRR1 small subunit processome component homolog
- Probable ATP-dependent RNA helicase kurz
- DDB1- and CUL4-associated factor 13
- U3 small nucleolar RNA-associated protein 18 homolog
- LD38375p
- LD41718p
- RE67794p
- Nucleolar protein 58
Sequence:
MSDDEEHYEPKAHKKLLQAIGSLGKVQHIQKSTRDERQSLQDEFQLVKGVSSAETDHAPRAVGLNDLVDILRTSTKHSQTGKKLKNIHGSKKVLQKPLEKPAADRIKRTIGYEGVTKKLGRWDAVVAQQRSAETQIFPLPSETVYVNTAANARPLNTRVKSNLAQELEANNRKLRELRKAQIGDTTDEKELAKQERLLLQKKLTRDELFARRKELAYLKMRESQKSAKARMQNKIKSKKFHKLQKRQKMLEQMKEFELLQKTDPEAALEKLNALEKSRVQERASLRHKNTGTWAKNLQIRAKYDKDVRKDLAEQLAVSRELTQKKQVSDSEDETTKKRVLPEEEDNDYDPFNPWTKRKATEQTENGNGESEGSNWRQYWTKRNKNEKLLEEHRRDLEGVQDNDEQEEKETIRKPLIEVKPAKKKLKKSKVKIENGWEVEDICPTDQKEAKASPNSKAIDDIFEKHEDHIRAKLNKKMEKLRERINKLKEVPVKGKKAKKKDVLQNLKSLALKKTKQQIEIDEPLNYEEDKNSQNNIPAHVEGNTESTEIPAVDTIDPNKVTTLVFTQKKGNSGGFNDALIDDEAAEYDEEDAAAERQLTISQAFEDDDIVADFNRDKSKDSELKNTELQLALPGWGSWAGAGISKEVMERRNKRLLLKLAAPEKRRDENKDNLYLNESASKQARQHMVSSIPFPFRSLADYEASIRAPVGRNFVPETAFRMLTRPAVITRKGQVIEPMTESELVKPDRRLRHIVDRRIKRIPKVPPKAKIA
Protein: Uncharacterized protein (A0A060WM81)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Carrier domain-containing protein
- N-acetylserotonin O-methyltransferase-like protein
- AB hydrolase-1 domain-containing protein
- Haloacid dehalogenase-like hydrolase domain-containing protein 3
- Sulfite oxidase
- Cytochrome b5 heme-binding domain-containing protein
- Oxidoreductase FAD/NAD
- Cytochrome b5 heme-binding domain-containing protein
- Cytochrome b5 heme-binding domain-containing protein
- Phospholipase A2
Sequence:
MSSTLLKMDVLHILQTNFVSIIIGFVVIILLWMNRGKQSNSRLPPGPAPIPLLGNLLRMDVKAPYKLYMELSKKYGSVFTVWLGSKPVVVISGFQAIKDAFVTQGEEFSGRANYPVIMTVSKGYGVLVSSGKRSKDLRRFSLMTLKTFGMGRRSIEERVQEEAKMLVKAFGEYRDSVVNPKALLCNCVGNVICSIVFGHRFENDDPMFQLIQKAVDAYFHVLSSPIGAMYNMFPRIVWCFPGNHHEMFAIVNKAKDYIQEQAEIRLKTLNISEPQDFIEAFLVKMLEEKDDPNTEFNNDNMVMTAWSLFAAGTETTSSTLRQSFLMMIKYPHIQESVQKEIDEVIGSRVPTVDDRVKMPYTDAVIHEVQRYMDLSPTSVPHKVMRDTEFYNYHIPEGTMVLPLLSSVLVDPKLFKNPDEFDPENFLDENGVFKKNDGFFAFGVGKRACPGEALARVELFLFFTSLLQRFTFTGTKPPEEINIEPLCSSFGRVPHSYDCYIELRTEE
Protein: Protocadherin-9 (Q8C421)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWIKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYGSNEGHFNNGGHMADIPLANLKSYKQAGGTIESPKEHQL
Protein: Chromosome associated protein G, isoform G (LD29017p) (B3DN53)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
Sequence:
MAKPKAKAGETEKPKTKAAGGKKRLAATKKTKKDGEKENEDQSVATTSDTSAELMYAIMRQAELKESLHKRYSKEMQQLYAKMGHESFRKAFINVLKAVLGAEEGNENANMALNFCATFVTSSDSDGTEPMLAETFHWLLTTYSSNPHIRYRICYFVNLILKELGPNAALDDHQCDDILEAMLDRVKDVSASVRKQAVLAMQRLQNPDNPSDVVVGAYMYHLTSDPSPNVRQCIITCMGRNYITIPHILERLWDVDEKVRRHTYVNMCNYPVRSYKVAQRLTLLEQGLNDTSATVRKTVINFMLKTWIESYQQNYVALIAALKLDSNEEELLRFRRVAKQMLRVIFQQTDIKQLIDQLPLSEDCELHRCIPHDSVTVELLLYWQCLSEYLETEAPEIESLLPELSVFCTYMDKFCQFQKPDMDKFAQVEFQNMLLSLVEILETYDLGDEIGRGNMRLLITNLLKDCLLDHKIVRVLVRCMEQLITDTNDRIQYFIEIIYELCELNTKQNDLIHDRSLINKLLDDLDTPLKMKISSLKVKILELEELEGNYVRQREYIRAQSVNDEKIAVTEEYTELIRPLLEKHGVIEMPTRPKLSKQERVLKGLYISYYMTASPHVHKLTPSLCQLYKDFICRYLPCAEVDIFEWSIKCGTTFSIFYEAYSREVFEVVVVQFCKNNNVRLCEASANCILELLDRYGVDYFNDLNQTGGSLSKTKRRQLYTMQELYDDDDGSQSQNNEQNSDILVVLGHYLERVQHRGVGMAIVRGLCRLVLRGHVDDRTDVLELLLKRYFNPNTEPIINQVLGLFFEELRRLNKHSLLQPCFLPTVWTCNYDSPLHGVQPEHLTKFFLEMTVQEMSTPQTNIHNKIAISFLQYIQNYFTERKDMCRLLAKELTNLSINVLNGPEVKAELLALAENLIQSELDPRMIKCIQNFKLVVNGSFNPPPRRNPDEGESDEEYETATVTTAESETAVPAQSQPPVTEESPNDVTQSAAITAVDATETPKAAAPPAPVPEPIVTTFGKDNIVGIRHLRRSMAISHSDAESLLGPQSPNPEESTESEAVETSKQNLRQPQMRRRLEMAIARSSKTPEKQPSTEEESSDEEISESPNAANKRKVVHLETPLRNGRKRVLRRSPSNSNSRSLRSRDSTALSSPRVSPRRKQQRLDNRSTRRQQMTKNTNSPTDSTSSVKENQIPPVIVIELDSDTESESNAKPESTPPKKPLKKTIPLIRSRPSSSTPKVTTRNEARAQRMNSKVMTRKRMSLEMNLSGGQLQVSTPKRVTRAVALSMSTDGKRSRRK
Protein: Ashwin (Q9BVC5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:18445686}.
Interaction partners:
- Protein FAM98B
- RNA transcription, translation and transport factor protein
- RNA-splicing ligase RtcB homolog
- ATP-dependent RNA helicase DDX1
- Protein archease
- Protein FAM98A
Sequence:
MAGDVGGRSCTDSELLLHPELLSQEFLLLTLEQKNIAVETDVRVNKDSLTDLYVQHAIPLPQRDLPKNRWGKMMEKKREQHEIKNETKRSSTVDGLRKRPLIVFDGSSTSTSIKVKKTENGDNDRLKPPPQASFTSNAFRKLSNSSSSVSPLILSSNLPVNNKTEHNNNDAKQNHDLTHRKSPSGPVKSPPLSPVGTTPVKLKRAAPKEEAEAMNNLKPPQAKRKIQHVTWP
Protein: Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed] (K7EKQ2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU369110}.
Interaction partners:
Sequence:
MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKAHAHAPATLMLMASSPPPPWMGWALRPRPARPRSRRSAALPQPTPPLTLPQSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLP
Protein: Eukaryotic translation initiation factor 3 subunit 7-like protein (Q587A3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit L
- Elongation initiation factor 2 alpha subunit, putative
- RNA-binding protein, putative
- CSN8/PSMD8/EIF3K domain-containing protein
- Translation initiation factor, putative
- protein-synthesizing GTPase
- Eukaryotic translation initiation factor 3 subunit E
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 3 subunit A
- Eukaryotic translation initiation factor 3 subunit 8, putative
Sequence:
MAFVLPQIHINEQSSWGPPEVQGGKIETTVGSLYHKREAVEPFDWLRVLEPVEGGRQREFTIVEDEKRNKILKSTRVKERRQVPDWSAPRRHQNSRRNFQNKPKRNITLPPDTVKVPSDAVILEQFRQAELAKMPNLTSLPTVSDISQHNRPPVYKNEMDKASCKAPIPLNEKETKVDFTRSDSFTDNVLRGILKSEPPGTYPIVVATDEVLALLMTCSRSVYSWHLHFYRVGRFYFISKVDGCNVEKQWVDETADVSRVPSETEVVETDRTSSLEAESSKVNNFFVAQSCTAARYQMDCEKSPFPGKHPRLYRYRRFVMHADTKDRYDLIVRCEVDAMQGDKHIRLFGLLEHCIKGEENDWRKMLASQTATCISEEYRRNAQKMARWIALCHLSGAHMKIGFISRCRKGAGVFDPLRHEVLATFTNDPSPLAAQLGIKVANMWTVADTIITAFVQSDFSEAALVKRSGDTSILLVEKCEEEFYEEEEDEEDDDEEDDDDDGEEDG
Protein: Transducin family protein / WD-40 repeat family protein (Q9FFF8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MFVRKFLQKSSGGQNPPPPIAPPPRGCLMAEDLDPHIITHSGIPSTASLLAFDPIQCLLAVGTLDGRIKVIGGDNIEAILASPKQLPFKNLEFMQNQGFLVSISNENEIQVWDLDLRQPASSLKWESNITAFAILHGTGYMYVGDEYGMVSVLNYSADEGKLLQLPYYVPTDALSEAAGLSSPIDYPVVGLLSQPCSKGTRLLIAFSNGLLFLWDASEDHVVLVRGNKDLPVEGKTVADSLEASHDELSNLELDGKEISSLCWASTDGSVLAVGYVDGDILFWDFSDGQKGKPSNHVVKLQLSSAEKRLPVIVMHWCLDVSRKSSGGKLFIYGGDIIGSDEVLTMLGLDWSSGMGGLKCVGRADLTLSGSFADMVLSPIASSRQSGVFLFLLTNPGQLQAYDDTSLASLMSQKENKISVSPLPYPMVVPTMDPHMTVATFSALNVNDKTSLALSEIVLAAKARTPRTPSGESAQWPLTGGVPSHVDDYKLERLYMAGYQDGSMRIWDATYPCLSLIYILEPKASVIDITGVDASVTAFCFCSKTSCLAVGNECGMVRLYKLVGHTSGGTLEVVTNTEKKGLAIVTTLTLWICYALSHAVGSLLVAHHLHQEDGPQWLAAFSFLSSPVCTLQFVQSTRRLAVGFKCGKVAVLDIGVPSVLFVTNSLSDSGSPIKSLYVKSSSAPTGSKSDPTDHNSINSEDDLLLCAMTKDGQTILLDGNTGKILASCLRPLKNPTAICMHIIENCYENYETPSEKPAENPSGKDKHENKSHIIKASESHSPDGEQNAVTETKLIDQIFANSLFLMCSEDALRLYTVKSLSQGSLESIMEVNLPRPCCWMGILKKDGRECAVLLFYRTGHIEIRSFPNLEVVGESSLLSLLRWNFKPNMEKTVCSDDFGHVVLVNGCEVAILSFLAHANGFRLPESLPLLHDKVLAAAADATFSHISVHKKNHDGAPKFLSNIIKGFRSSTEQKMDQVQDFSHLGNIFSNPPYLKPSDTGGDDEKIVELNIDDIEIDEPVIILPLTEKDKKEKKDKRTDKEKLFDGASSDAQPKTRTVDEIKSKYRKAGETSAIASQAKDKLHERGEKLERISQRTAELQDNAENFASMAHELAKQMEKRKWWNI
Protein: 2-aminoadipate transaminase (A0A1D8PPA8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Phosphomutase-like protein 3
Sequence:
MINFFKGHPTRELLPVNEIADSYKRVLLDSDYLSYDTDPNNQHPLQYGTDPGNLDVREVIAQWVNKKFGAQVSDPNCINLTAGASYGVGNILTSVTSPKITQRVFVVTPTYFLINSCFVDVGLDDRLTAIEETHNGKYSIDLVYLEQQLQKYSQDLEPVHDDINVFPDPVRGTRKYYRFVMYLVPTFSNPGGLNYTLETRQKLVEIARKYDLLLISDDVYEFLDYTDSKPLPRLNQLDKAGATKYGNTISNATFSKIIAPGLRVGWQETATPKLVDQLSITGSNRSGGTPNQLSTLVVADLIKTGTIDEIIAKFKNVYKERVAVLKESIAKYLPQDTQVYGGDGGYFVWVVTPSANCFDVVAKLAKQNVVLAGGEHFEVTGDKRNWGQHCVRLSISYLTTEEIQQGIKIWGELLE
Protein: Parasite-infected erythrocyte surface protein (Q8I488)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MLLFFAKLVVFTFFFWLLKYGKTRSYPKSGHKGHTKLNQPVVRTLADFNDMFANQKNTFNFLKHINHYKNEQDTNNTHTPNHDEYSHNLPKNHEESNANMNNHNSFNDKSVNKKEAFDQFLQTLLNNYEIMHKEDESKESNQHNYKEGPSYEDKKNMYKEILKGYYNVFFENYANDTESNVHNKPEEVHKHEEIHKHRKLHKHEEVHKPEEFHKPEEFHKHEKVHKHEEVHKPEEVHKHEENHKHEENHKPQMVGQAPPEKEIRQESRTLILGSFPQAGEILREDLWNKEDNKFSYALDPNDYASIEDKLLGSIFGYFKKNHDNLVKHLLQQINTYKHKYMELKEQYINEVMKLKKIYNKSIMVIFIASCISILGPVMLHMHQNNPEEFFATILSFSISLGLHNLLLT
Protein: E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (O35445)
Organism: Mus musculus (Mouse)
Function: Membrane-bound E3 ubiquitin-protein ligase that mediates ubiquitination of target proteins. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4 (By similarity). Mediates ubiquitination of PXN/paxillin,thereby regulating cell motility and localization of PXN/paxillin (By similarity). Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N (By similarity). Mediates the 'Lys-48'-linked polyubiquitination of STING1 at 'Lys-150' leading to its proteasomal degradation; the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses (By similarity). Catalyzes ubiquitination and subsequent degradation of ATG4B, thereby inhibiting autophagy.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12861019}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q99942}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q99942}; Multi-pass membrane protein {ECO:0000255}. Note=Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles. {ECO:0000250|UniProtKB:Q99942}.
Interaction partners:
- E3 ubiquitin-protein ligase RNF185
- Derlin-1
- Derlin-2
- Cystic fibrosis transmembrane conductance regulator
- E3 ubiquitin-protein ligase AMFR
- Protein sel-1 homolog 1
- E3 ubiquitin-protein ligase RNF26
- Erlin-1
- Erlin-2
- Derlin-3
Sequence:
MAAAEEEDGGPEGPNRERGGASATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPDRQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDAGGFHFSFGVGAFPFGFFTTVFNAHEPFRRGAGVDLGQGHPASSWQDSLFLFLAIFFFFWLLSI
Protein: Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); Capsid protein p30 (CA); Nucleocapsid protein p10 (NC-pol); Protease p14 (PR) (EC 3.4.23.-); Reverse transcriptase/ribonuclease H p80 (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase p46 (IN) (EC 2.7.7.-) (EC 3.1.-.-)] (A1Z651)
Organism: Xenotropic MuLV-related virus (isolate VP62) (XMRV)
Function: Plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.
Subcellular location: [Gag-Pol polyprotein]: Host cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.; SUBCELLULAR LOCATION: [Matrix protein p15]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Capsid protein p30]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Nucleocapsid protein p10]: Virion {ECO:0000305}.
Interaction partners:
Sequence:
MGQTVTTPLSLTLQHWGDVQRIASNQSVDVKKRRWVTFCSAEWPTFNVGWPQDGTFNLGVISQVKSRVFCPGPHGHPDQVPYIVTWEALAYDPPPWVKPFVSPKPPPLPTAPVLPPGPSAQPPSRSALYPALTPSIKSKPPKPQVLPDSGGPLIDLLTEDPPPYGAQPSSSARENNEEEAATTSEVSPPSPMVSRLRGRRDPPAADSTTSQAFPLRMGGDGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNAAFPLERPDWDYTTTEGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIRREIEEKEERRRAEDEQRERERDRRRHREMSKLLATVVIGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLGDXGGQGQEPPPEPRITLKVGGQPVTFLVDTGAQHSVLTQNPGPLSDKSAWVQGATGGKRYRWTTDRKVHLATGKVTHSFLHVPDCPYPLLGRDLLTKLKAQIHFEGSGAQVVGPMGQPLQVLTLNIEDEYRLHETSKEPDVPLGSTWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSEQDCQRGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQRWLTEARKETVMGQPTPKTPRQLREFLGTAGFCRLWIPGFAEMAAPLYPLTKTGTLFNWGPDQQKAYQEIKQALLTAPALGLPDLTKPFELFVDEKQGYAKGVLTQKLGPWRRPVAYLSKKLDPVAAGWPPCLRMVAAIAVLTKDAGKLTMGQPLVILAPHAVEALVKQPPDRWLSNARMTHYQAMLLDTDRVQFGPVVALNPATLLPLPEKEAPHDCLEILAETHGTRPDLTDQPIPDADYTWYTDGSSFLQEGQRRAGAAVTTETEVIWARALPAGTSAQRAELIALTQALKMAEGKKLNVYTDSRYAFATAHVHGEIYRRRGLLTSEGREIKNKNEILALLKALFLPKRLSIIHCPGHQKGNSAEARGNRMADQAAREAAMKAVLETSTLLIEDSTPYTPPHFHYTETDLKRLRELGATYNQTKGYWVLQGKPVMPDQSVFELLDSLHRLTHLSPQKMKALLDREESPYYMLNRDRTIQYVTETCTACAQVNASKAKIGAGVRVRGHRPGTHWEVDFTEVKPGLYGYKYLLVFVDTFSGWVEAFPTKRETAKVVSKKLLEDIFPRFGMPQVLGSDNGPAFASQVSQSVADLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLTLASGTRDWVLLLPLALYRARNTPGPHGLTPYEILYGAPPPLVNFHDPEMSKLTNSPSLQAHLQALQAVQQEVWKPLAAAYQDQLDQPVIPHPFRVGDAVWVRRHQTKNLEPRWKGPYTVLLTTPTALKVDGISAWIHAAHVKAATTPPAGTAWKVQRSQNPLKIRLTRGAP
Protein: Putative glycosyltransferase HOC1 (EC 2.4.-.-) (M-Pol II subunit Hoc1p) (Mannan polymerase II complex HOC1 subunit) (P47124)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins.
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:9055074, ECO:0000269|PubMed:9430634}; Single-pass type II membrane protein {ECO:0000269|PubMed:9055074, ECO:0000269|PubMed:9430634}.
Interaction partners:
- Mannan polymerase complexes subunit MNN9
- Probable alpha-1,6-mannosyltransferase MNN10
- Mannan polymerase II complex ANP1 subunit
- Probable alpha-1,6-mannosyltransferase MNN11
- Mannan polymerase I complex VAN1 subunit
- Alpha-1,2-mannosyltransferase MNN2
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein uL29m
Sequence:
MAKTTKRASSFRRLMIFAIIALISLAFGVRYLFHNSNATDLQKILQNLPKEISQSINSANNIQSSDSDLVQHFESLAQEIRHQQEVQAKQFDKQRKILEKKIQDLKQTPPEATLRERIAMTFPYDSHVKFPAFIWQTWSNDEGPERVQDIKGMWESKNPGFAHEVLNHDVINALVHHYFYSIPEILETYEALPSIILKIDFFKYLILLVHGGVYADIDTFPVQPIPNWIPEELSPSDIGLIVGVEEDAQRADWRTKYIRRLQFGTWIIQAKPGHPVLREIISRIIETTLQRKRDDQLNVNLRNDLNIMSWTGSGLWTDTIFTYFNDFMRSGVREKVTWKLFHNLNQPKLLSDVLVFPKFSFNCPNQIDNDDPHKKFYFITHLASQFWKNTPKVEQK
Protein: Inositol 3-kinase (EC 2.7.1.64) (Myo-inositol kinase) (Protein LOW PHYTIC ACID 3) (Q5GA22)
Organism: Zea mays (Maize)
Function: Kinase that phosphorylates myo-inositol to produce multiple myo-inositol monophosphates, Ins(1)P, Ins(3)P, Ins(4)P, Ins(5)P and Ins(6)P. Participates in phytic acid biosynthesis in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.
Interaction partners:
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Inositol-3-phosphate synthase
- histidinol-phosphatase
- Inositol-1-monophosphatase
- inositol-3-phosphate synthase
- Inositol-3-phosphate synthase 1
- Inositol-3-phosphate synthase 1
- Inositol-3-phosphate synthase
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Inositol oxygenase
Sequence:
MPLAAEPDDAHEERENQQLLITTKGGPGLEGLVVGSYCHDVLIRGGRIVGETLGGAAAFVSNVLDAASPQGAALNETSPFVVVAKVGHDFIYARAPASARHPPLLCSSPTTSFHAQFSETAASAHAPDRELRRVRACDPIYPADLPDRRFAYGLAVGVAGEVLPETLEQMIRLCRTVLVDAQALIRAFDGDGAVGHVALGDTPYARLLPRVAFVKASSEEAPYVGVETTRRQCCVIVTEGRDGCRLYWDGGEAHVAPFPAVQVDPTGAGDSFLAGFAAGLLWGLSATDAALLGNFFGAAAVSQVGVPTFHPKMLQAVKEILEEKTRKRSSPCMNGASFTLEKSNMHNELHAALQEAAVLMSEQQQADPANGSGGDICSA
Protein: Vascular endothelial growth factor receptor kdr-like (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor-A) (Kinase insert domain receptor-like) (Protein-tyrosine kinase receptor flk-1) (Vascular endothelial growth factor receptor 4) (VEGFR-4) (Q8AXB3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Vascular endothelial growth factor C
- Vascular endothelial growth factor A-A
- Neuropilin-1a
- C-fos induced growth factor
- Fli-1 protein
- Vascular endothelial growth factor Ab
- Platelet endothelial cell adhesion molecule isoform X1
- Neuropilin 1b.
- Protein tyrosine kinase 2ab
- Placenta growth factor
Sequence:
MTPLKTSVKAFFTLHVLFSCISHGLVEGSRLPDPQLLPDGDTHLQHVGGTLTLICRGSTALHWRLASRNVSSVRIESCEERLHKHCSKLVIHNLRHNDTGIYSCSHKKSSDHEVSTYVFVKDPHHPFVEAYSLPHPLFAYRNDPYFVVPCRTTYPNQNVILETQMNPMADDVKRGVQWDPKKGFTVPLKPYDSYHLITCLTRVDNAEFSSVYLLKRLTMEIKNLAIEPERPRVLVGDTLILNCSAETTYNGRIHFEWEFHKERINRTHHFSTTPVQLAQIMVMSKALIVPNVTMEDKGTYTCTGSIEFKKLQMSTKVIVYEHPFLNVTHNKRKFTSTVEGRRVQFEPRVNAVPAPDRVLWYKDGVAISENSTCYETAGYNLTIKQVRQKDAGIFTIALSNQERGLYRNISYKLEVRVKPKIFEEDVAPAGPQTFRYDQRHKLTCTAFGIPMPNITWFWQPCDPSANLTECKLYTDPLPIENVDDHFPQNPIKDVNSKVGLLKSKNRTISTLVVKTANVSGVYSCTARNELGNRTMRIPFYVDDHPQPFEIEPSTAVAGDDITLTCRGTRYLYDRLTWYDPLGHKVPKDETTLRIEPYTISLSIKLPNVSRNHTLGYECQALKINTNKVVNVTSALTIDERQGPWLMQNLTNQDVNSSSTLTLACLAYGVPAPFITWYKDKTPVTEGPGITLKDDGTLIIERVKKDDEGIYECRASNDGGEAKTSAVITVVGEDGKPNIEVIILVSTGAAATFLWIMLILFIRKLRKPSSADLKTGYLSIIMDPEQMPLDEQCDRLPYDSNKWEFPQDRLRLGKTLGHGAFGKVVEASAFGIDKISTCKTVAVKMLKVGATNNEWRALMSELKILIHIGHHLNVVNLLGACTKRGGPLMIIVEFCKYGNLSNYLRSKRGDFVVYKSQDGKAVRSSSGCDLSELIKRRLESVASTGSSASSGFIEDKSYCDSEEEEEEQEDLYKKVLTLEDLICYSFQVAKGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDVYKDPDYVRKGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGDLLQASVQQEGKHYIPINTALLTKADPSNQSPTEETSTRPVSLRDSGTAWNIKIRPESVKTFDEVILENGTNKIHEGGQSDSGIGLSSDDLKTLKRLESLARPRSFMSRAMKRKSKESVLLEGEMDKYPPLVPSLSLEDSSLDSEMECHSPPPDYNYVVRYSTPPV
Protein: Ig-like domain-containing protein (Q9XWM1)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MVLAPFFEKAPSLIIAPDGSVLFECICNANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFTVTLHIKNPTQEDQGVYKVTATNTHGSHSVEQQYIYKCTGKEVFKTLD