wanglab/gogpt-training-data huggingface dataset:
Protein: Cell junction protein VAB-9 (Transmembrane protein 47) (G5ED30)
Organism: Caenorhabditis elegans
Subcellular location: Cell junction {ECO:0000256|ARBA:ARBA00004282}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Tight junction protein ZO-1
- Apical junction molecule ajm-1
- Clc-like protein
- Juxtamembrane domain-associated catenin
- cGMP-dependent protein kinase interacting domain-containing protein
Sequence:
MVAVQRTTIEAVSAVRPLKIISLICLVIAVGLMIVALCSTSWLKTGSFRTGLFKECTSTNEPTHAAPFPGAPAPGSCHKPSRNSGFLTAAAVLLIVALFLTALSTIFNIVGLSKSDVRGKYRWYRIATMISGFSVLLELTALIMFPAAFYVKISDYGSRRNWEVDWSYGIAWGATLFTIGATIMLICDKEHEEVYYKEKTIYNPPPELSDR
Protein: Small polypeptide DEVIL 16 (Small polypeptide ROTUNDIFOLIA 4) (Small polypeptide ROT-FOUR) (Q7XXN8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs (e.g. leaves) and coordinating socket cell recruitment and differentiation at trichome sites. Regulates the positional cue and cell proliferation along the body axis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15125775, ECO:0000269|PubMed:20826883}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Small polypeptide DEVIL 1
- Protein BRICK 1
- Small polypeptide DEVIL 4
- Small polypeptide DEVIL 2
- Small polypeptide DEVIL 15
- Small polypeptide DEVIL 5
- Small polypeptide DEVIL 14
- Small polypeptide DEVIL 17
- 3-epi-6-deoxocathasterone 23-monooxygenase CYP90C1
- Small polypeptide DEVIL 23
Sequence:
MAPEENGTCEPCKTFGQKCSHVVKKQRAKFYILRRCIAMLVCWHDQNHDRKDS
Protein: Sulfite reductase [NADPH] flavoprotein alpha-component (SiR-FP) (EC 1.8.1.2) (P38038)
Organism: Escherichia coli (strain K12)
Function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
Interaction partners:
- Sulfate adenylyltransferase subunit 1
- Sulfate adenylyltransferase subunit 2
- Phosphoadenosine 5'-phosphosulfate reductase
- Cysteine synthase A
- Sulfite reductase hemoprotein beta-component
- Sulfate/thiosulfate import ATP-binding protein CysA
- Thiosulfate-binding protein
- Adenylyl-sulfate kinase
- Sulfate transport system permease protein CysW
- Cysteine synthase B
Sequence:
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGMRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKDGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
Protein: Tetratricopeptide repeat domain 39A (E9PHX9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKAAYLSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDE
Protein: Transcription factor SOX (O57399)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR038098}.
Interaction partners:
- Glycogen [starch] synthase
- POU domain protein
- POU domain protein
- Catenin beta-1
- CTNNB1 binding N-teminal domain-containing protein
Sequence:
MVQQTEHSETESSREATDTEESELMACSPVPLKSVKADWCKTATGHIKRPMNAFMVWSKVERRKIMEQSPDMHNAEISKRLGKRWKLLKDSEKIPFIREAERLRLQHMADYPDYKYRPKKKPKLDSSTKPAAQSPEKTNIKPVKAPGKKFAKLKTMKAVTTRPSHDPRYDYVFTSFTTSKSVKMEYSDEDDDEEDYEEEVFSRIKMEEDEEPIPYNIAKVPASPTLSSTAESEGASMYEESRNANAAPTRLFYNFKNITKQNTICPASLSPASSFRSVSTSSSSSEDADDLLVDFSLNLASSAHGVELGTSNSGNLSLSLVDKDLDSFSEGSLSSHFEFPDYCTPELSEMIAGDWLDANFSDLVFTY
Protein: Mitogen-activated protein kinase pmk-3 (EC 2.7.11.24) (Stress-activated protein kinase pmk-3) (p38 MAP kinase 3) (O44514)
Organism: Caenorhabditis elegans
Function: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Involved in axon regeneration after injury, probably downstream of dlk-1 and mkk-4 and upstream of mak-2. May phosphorylate mak-2. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord.
Subcellular location: Nucleus {ECO:0000269|PubMed:11703092, ECO:0000269|PubMed:26657059}. Cytoplasm {ECO:0000269|PubMed:26657059}. Cell projection, axon {ECO:0000269|PubMed:26657059}. Cell projection, dendrite {ECO:0000269|PubMed:26657059}. Cell projection, cilium {ECO:0000269|PubMed:26657059}.
Interaction partners:
- MAP kinase-activated protein kinase mak-2
- Tyrosine-protein phosphatase vhp-1
- Cytosolic carboxypeptidase 6
- Dual specificity mitogen-activated protein kinase kinase sek-1
- Forkhead box protein O
- Dual specificity protein phosphatase lip-1
- Dual specificity mitogen-activated protein kinase kinase mek-1
- Protein skinhead-1
- ETS domain-containing protein
- Putative ribosomal protein S6 kinase alpha-2
Sequence:
MASVPSSSSLPVSHVRRHEDVSTPSAPPTKRSNNQSQPPESYEPNTWLQQQREQEQQKKLAAENIKKQSIEATGNNEMVGEEEEDILSKPCGPHKRRFQFVMIRNITFAIPEGYDVEPNSIEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTSLTQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIENDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLAEFSLPEDEPRADHIFDLDDSQARTRFEWRDAVWKEIMNYKRLSSSPLIPGEADR
Protein: Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) (Q9UBF2)
Organism: Homo sapiens (Human)
Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi. {ECO:0000250}.
Interaction partners:
- Coatomer subunit beta'
- Coatomer subunit beta
- Coatomer subunit zeta-1
- Coatomer subunit alpha
- Coatomer subunit delta
- Coatomer subunit epsilon
- Coatomer subunit zeta-2
- Coatomer subunit gamma-1
- N-terminal kinase-like protein
- Mesoderm-specific transcript homolog protein
Sequence:
MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMALNATYIFNGLTVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKPEKLAPSRQDIFQEQLAAIPEFLNIGPLFKSSEPVQLTEAETEYFVRCIKHMFTNHIVFQFDCTNTLNDQLLEKVTVQMEPSDSYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGSFSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVGDTFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGIFRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG
Protein: Keratinocyte differentiation factor 1 (Q8NAX2)
Organism: Homo sapiens (Human)
Function: Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:A2A9F4}. Cell junction {ECO:0000250|UniProtKB:A2A9F4}. Note=Localized at cell borders in single layered keratinocytes. Localized at cell borders in the basal and spinous layers but is more diffusely localized in the granular layer. Colocalized with actin near the cell membrane, especially in cellular protrusions (By similarity). {ECO:0000250|UniProtKB:A2A9F4}.
Interaction partners:
- Ras-related protein Rab-25
Sequence:
MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPALESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTFASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASHDSSFQGTDTDSSGAPLLQVYC
Protein: Sorting nexin 7 (Sorting nexin-7 isoform X1) (A0A0R4IBS8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSVPAVDNTVSSGNASVAIPADMSGQMLDLDEDDDLEVFSKDTTITDGSSFNASMQTSPASMINQYKFEEEEEDVGTKDIFVTVDNPESHVTAIETYITYRVMTKTTRSEFDSSEFEVRRRYQDFLWLKGRLEEAHPTLIVHPLPEKFVMKGMVERFNEDFIETRRRALHRFLNRIAEHPIFSSTEDFKIFLTAASEELISHKKQGPGFLSRMGETVKAVAASVRGVRNRPEEFNDMQEYVEAFSQKINSLDKVTQRIIREQREYLEELKECGPTYTLWSNSEQELAEPLKNMADCLDRCYKETDEQVKQLNDQLSPALHEYVLCTETLKAVIRRRDNIQADFEAKTEALATKKADREADSKVLSLAWDSLVGRSPEEVKQQRQQKLKAEIKEMKDDLEKLEDRLEWANNALKSDWTRWNKVMRTDLRSAFVDTAERNVSYYEKCLAIWESFLHSQRTDAEANGKADFS
Protein: Nuclear RNA export factor 1 (Protein small bristles) (Protein tip-associating) (Q9U1H9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm. In ovarian follicle cells, plays a role in transposable element silencing regulation by enabling the nuclear export of flamenco (flam) transcripts and subsequent piRNA biogenesis.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:14729961}. Cytoplasm {ECO:0000269|PubMed:14729961}. Nucleus envelope {ECO:0000269|PubMed:14729961}. Note=Localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:14729961}.
Interaction partners:
- NTF2-related export protein
- LD24793p
- Uncharacterized protein
- THO complex subunit 5
- Protein Rae1
- RNA and export factor binding protein 2, isoform A
- Nuclear pore complex protein Nup214
- FI21285p1
- Nuclear pore complex protein Nup153
- Nuclear pore glycoprotein p62
Sequence:
MPKRGGGSSQRYNNNVGNGGGRYNAPEDFDDFDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIKLRPEDLRRWDEDDDMSDMTTAVKDRPTSRRRGSPIPRGKFGKLMPNSFGWYQVTLQNAQIYEKETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDDYEAAERIQHLGKNGHLPDGYRLMPRVRSGIPLVAIDDAFKEKMKVTMAKRYNIQTKALDLSRFHADPDLKQVFCPLFRQNVMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSEQGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISMPSASQAGRLNSFWKFNRNLRRLLNGEENRTRNLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVFTVTGLFKELNDETNNPASMELYDVRHFARTYVVVPQNNGFCIRNETIFITNATHEQVREFKRSQHQPAPGAMPSTSSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPGAQDESTKMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAFMK
Protein: Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Q7T1S9)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
GSGRGRPRSLPALPLLGSLLQLAGHPQLHLRLWRLQGRYGSLYALWMGSHYVVVVNSYRHAREVLLKKGKDFAGRPRTVTTDLLSRGGKDIAFASYGPLWKFQRKLVHTALSMFGEGSLALERIICREAASLCETLSAAQDTALDMAPELTRAVTNVVCSLCFNSSYRRGDPEFEAMLEYSQGIVDTVAKESLVDIFPWLQIFPNKDLALLKKCLQVRDQLLQQKFTEHKEAFCGDTVKDLMDALLQVRLSAENSSPLEPGLELTDDHLLMTVGDIFGAGVETTTTVLKWAVLYLLHYPEIQRKIQEEMDHKIGQVRHPHLSDRPLLPYLEATISEVLRIRPVSPLLIPHVSLADTSIGEYSIPRGARVIINLWSVHHDEKEWDKPEEFNPGRFLDERGQHIHSPSPSYLPFGAGIRVCLGKVLAKMELFLFLAWVLQRFTLECPEDQPLPSLEGKFGVVLQVQKFQVKARLREAWRAAS
Protein: CTD small phosphatase like 2 (H0YMH7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDS
Protein: DNA-directed RNA polymerases IV and V subunit 5B (DNA-directed RNA polymerase 23kD subunit) (Q9ZVB9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA-directed RNA polymerases II, IV and V subunit 8B
- DNA-directed RNA polymerases II and V subunit 8A
- DNA-directed RNA polymerases II and V subunit 6B
- DNA-directed RNA polymerases IV and V subunit 3B
- DNA-directed RNA polymerases II, IV and V subunit 10
- DNA-directed RNA polymerases II, IV and V subunit 6A
- DNA-directed RNA polymerases II, IV and V subunit 9B
- DNA-directed RNA polymerases II, IV and V subunit 3
- DNA-directed RNA polymerases II, IV and V subunit 9A
- DNA-directed RNA polymerases II, IV and V subunit 11
Sequence:
MEGKGKEIVVGHSISKSSVECHKYYLARRTTMEMLRDRGYDVSDEDINLSLQQFRALYGEHPDVDLLRISAKHRFDSSKKISVVFCGTGIVKVNAMRVIAADVLSRENITGLILVLQSHITNQALKAVELFSFKVELFEITDLLVNVSKHVLRPKHQVLNDKEKESLLKKFSIEEKQLPRLSSKDPIVRYYGLETGQVMKVTYKDELSESHVTYRCVS
Protein: Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein) (Q8JZU2)
Organism: Mus musculus (Mouse)
Function: Mitochondrial electroneutral antiporter that exports citrate from the mitochondria into the cytosol in exchange for malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis-aconitate and to a lesser extend cis-aconitate, maleate and succinate. In the cytoplasm citrate is important in the regulation of glycolysis through a feedback mechanism and in the production of acetyl-CoA which is needed for the synthesis of fatty acids, sterols, prostaglandins, dolichol and coenzyme Q (CoQ). Required for proper neuromuscular junction formation.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:12865426}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:18775783}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Citrate synthase
- Citrate synthase, mitochondrial
- ATP-citrate synthase
- 39S ribosomal protein L40
- Transport and Golgi organization 2 homolog
- DNA polymerase epsilon subunit 2
- UPF0235 protein C15orf40 homolog
- Progranulin
- Developmentally-regulated GTP-binding protein 1
- STING ER exit protein
Sequence:
MAAPRGPRALSAAAPGSGKPKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSRRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSSNPKYRGFFHGVREIIREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDNHNKPMNPLITGVFGATAGAASVFGNTPLDVIKTRMQGLEAHKYRNTLDCGLKILKNEGPKAFYKGTVPRLGRVCLDVAIVFIIYDEVVKLLNKVWKTD
Protein: Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (D3Z941)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
- Lysine--tRNA ligase
- Isoleucine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Bifunctional glutamate/proline--tRNA ligase
- Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
- Glutamine--tRNA ligase
- Aspartate--tRNA ligase, cytoplasmic
- Tyrosine--tRNA ligase, cytoplasmic
- Arginine--tRNA ligase, cytoplasmic
Sequence:
MRLFVSEGSPGSLPVLAAAARARGRAELLISTVGPEECVVPFLTRPKVPVLQLDSGNYLFSASAICRYFFLLCGWEQDDLTNQWLEWEATELQPVLSAALYCLVVQGKKGEDVLGPLRRVLTHIDHSLSRQNCPFLAGDTESLADIVLWGALYPLLQDPAYLPEELGALQSWFQTLSTQEPCQRAAETVLKQQGVLALRPYLQKQPQPQPLPPEGRAVSNEPEEEELATLSEEDIIAAVAAWEKGLENLPPLQPQQHPVLPVPGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKAMEEGLTPQEICDKYHAIHVDIYRWFNISFDTFGRTTTPLQTKITQDIFQRLLTRGFVLQDTVEQLRCEQCARFLADRFVEGVCPFCGYEEARGDQCDKCGKLINAIELKRPQCKVCRSHPVVKSSKHLFLDLPKLEKRLEDWLGKTMPGSDWTPNARFIIRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWWKNPEQVDLYQFMAKDNVPFHGLVFPCSALGAEDNYTLVKNLIATEYLNYEDGKFSKSRGIGVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLIKNNSELLNNLGNFINRAGMFVSKFFGGCVPEMVLTHDDRRLVAHVSWELQRYHQLLEKVRIRDALRSILTISRHGNQYIQVNEPWKRIKGDEMDRQRAGTVTGMAVNIAALLSVMLQPYMPTVSSTIQTQLQLPEAACRILATSFICTLPAGHRIGTVSPLFQKLENDQIENLRQRFGGGQAKGSPKPAVVEAVTTAGSQDIQVLVDEVTKQGNIVRELKAQKADKNQVAAEVAKLLDLKKQLALAEGKPIETPKGKKKK
Protein: MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Q0WYX8)
Organism: Gallus gallus (Chicken)
Function: Required for radial migration of cortical neurons in the superficial layer of the neocortex.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16782075}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:16782075}. Note=Associated with lipid rafts. {ECO:0000250|UniProtKB:Q8NFP4, ECO:0000269|PubMed:16782075}.
Interaction partners:
- Neuroligin 2.
- Neuroligin 1
- Neuroligin 4
- Calsyntenin 3.
- Gamma-aminobutyric acid receptor subunit gamma-3
Sequence:
MEMICVLFLSLVPAYSRGQGVYAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIRSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR
Protein: UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) (Q92575)
Organism: Homo sapiens (Human)
Function: Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16968747}; Peripheral membrane protein {ECO:0000269|PubMed:16968747}. Nucleus envelope {ECO:0000269|PubMed:16968747}. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER. {ECO:0000269|PubMed:16968747}.
Interaction partners:
- Transitional endoplasmic reticulum ATPase
- UBX domain-containing protein 6
- UBX domain-containing protein 8
- NSFL1 cofactor p47
- UBX domain-containing protein 1
- UBX domain-containing protein 2A
- Small VCP/p97-interacting protein
- Ubiquitin conjugation factor E4 A
- FAS-associated factor 2
- Ubiquilin-1
Sequence:
MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNSFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSSGDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRKRVLEKRGDDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM
Protein: Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain) (Protein EGFL6-like) (Q6UXI9)
Organism: Homo sapiens (Human)
Function: Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Trapped on the cell surface or in the extracellular matrix. {ECO:0000250}.
Interaction partners:
- Integrin alpha-8
- Integrin beta-1
- FRAS1-related extracellular matrix protein 1
- FRAS1-related extracellular matrix protein 2
- Extracellular matrix organizing protein FRAS1
Sequence:
MDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSIGLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSMANCQYGCDVVKGQIRCQCPSPGLQLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNIRGSYKCKCKEGYQGDGLTCVYIPKVMIEPSGPIHVPKGNGTILKGDTGNNNWIPDVGSTWWPPKTPYIPPIITNRPTSKPTTRPTPKPTPIPTPPPPPPLPTELRTPLPPTTPERPTTGLTTIAPAASTPPGGITVDNRVQTDPQKPRGDVFIPRQPSNDLFEIFEIERGVSADDEAKDDPGVLVHSCNFDHGLCGWIREKDNDLHWEPIRDPAGGQYLTVSAAKAPGGKAARLVLPLGRLMHSGDLCLSFRHKVTGLHSGTLQVFVRKHGAHGAALWGRNGGHGWRQTQITLRGADIKSVVFKGEKRRGHTGEIGLDDVSLKKGHCSEER
Protein: 40 protein (Helicase-primase) (O41957)
Organism: Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68)
Interaction partners:
Sequence:
MCRLQWHDVQVLNVSLYNISMPHKTGIWVITALKTATWDLCAFFRLEQLSETVPHIPGEMDPRPMSPFMHNENICLFDLLMRYQSPLLRKLINLGRMKLGTSGKEILAVEEVETALTHQLTGGYLMCFGTTIRQEDDRGKLTSWKEHLLKDFNLCQPQVYLKTCRGVYVYDSRDIPAKKGRLDSLTIEDIFSPVDTILHVAGSPITVRTFETPFHILWIDKDSVWNGYLSEFFRALYVKLYGNFIGLKPILAYVFPAAVESPTFFNTIFTSFPFLCLRFGKPVKTSCVHLQKDCLKILAKLPNVIRSPLADKVLDIKAQKKPITSMWPLLTKELNGSFAEDNKVIITKECNVVEIDFTKAFLISCNMPYAVYWHEQMVEIVNVITDEMKDSLVSRYNEFLYAIISSGNKHNFTWVSISKCTVHMVGPDLVNDTQFLDEIFHRLSSVYNGHVGDITVSSQKLKVAMFTDILDEIKLIKPLCLEENRQPETFQSACEDILRYSLCLCKHSKEDILWKILLTMWQQRRNTSFWLKETMNIEHPTIRPKGLFFTIAPAFYLHTKHGMSFWMQDKPLPSCFDYTPYIMELCDILQLNDEERDMILSNYETLLNLS