wanglab/gogpt-training-data huggingface dataset:
Protein: Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (Q63739)
Organism: Mus musculus (Mouse)
Function: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:10747914}; Lipid-anchor {ECO:0000269|PubMed:10747914}. Early endosome {ECO:0000269|PubMed:10747914}. Endoplasmic reticulum {ECO:0000269|PubMed:10747914}. Cytoplasm {ECO:0000269|PubMed:10747914}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:10747914}. Nucleus {ECO:0000250|UniProtKB:Q78EG7}. Note=And mitotic spindle.
Interaction partners:
- PHD finger protein 3
Sequence:
MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
Protein: DNA 5'-3' helicase (EC 5.6.2.3) (A8MX75)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHR
Protein: Peroxisomal succinyl-coenzyme A thioesterase (EC 3.1.2.3) (Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (EC 3.1.2.2) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib) (Q8N9L9)
Organism: Homo sapiens (Human)
Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Functions as a peroxisomal succinyl-coenzyme A thioesterase that can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs.
Subcellular location: Peroxisome {ECO:0000269|PubMed:16940157}.
Interaction partners:
- Cytosolic acyl coenzyme A thioester hydrolase
- Acyl-coenzyme A thioesterase THEM4
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Fructose-1,6-bisphosphatase 1
- Acyl-coenzyme A thioesterase THEM5
- Acyl-coenzyme A thioesterase 1
- Very-long-chain enoyl-CoA reductase
- Fructose-1,6-bisphosphatase isozyme 2
- ATP-dependent 6-phosphofructokinase, liver type
- ATP-dependent 6-phosphofructokinase, muscle type
Sequence:
MSATLILEPPGRCCWNEPVRIAVRGLAPEQRVTLRASLRDEKGALFRAHARYCADARGELDLERAPALGGSFAGLEPMGLLWALEPEKPFWRFLKRDVQIPFVVELEVLDGHDPEPGRLLCQAQHERHFLPPGVRRQSVRAGRVRATLFLPPGPGPFPGIIDIFGIGGGLLEYRASLLAGHGFATLALAYYNFEDLPNNMDNISLEYFEEAVCYMLQHPQVKGPGIGLLGISLGADICLSMASFLKNVSATVSINGSGISGNTAINYKHSSIPPLGYDLRRIKVAFSGLVDIVDIRNALVGGYKNPSMIPIEKAQGPILLIVGQDDHNWRSELYAQTVSERLQAHGKEKPQIICYPGTGHYIEPPYFPLCPASLHRLLNKHVIWGGEPRAHSKAQEDAWKQILAFFCKHLGGTQKTAVPKL
Protein: RNA-binding protein MEX3D (RING finger and KH domain-containing protein 1) (RING finger protein 193) (TINO) (Q86XN8)
Organism: Homo sapiens (Human)
Function: RNA binding protein, may be involved in post-transcriptional regulatory mechanisms.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. {ECO:0000250}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein K
- mRNA-decapping enzyme 1A
- Protein argonaute-1
Sequence:
MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALARECVVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFS
Protein: Transmembrane protease serine 3 (EC 3.4.21.-) (Q8K1T0)
Organism: Mus musculus (Mouse)
Function: Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival. Activates ENaC (in vitro).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12393794, ECO:0000269|PubMed:21454591}; Single-pass type II membrane protein {ECO:0000269|PubMed:12393794, ECO:0000269|PubMed:21454591}.
Interaction partners:
- Pejvakin
- Transmembrane channel-like protein 1
Sequence:
MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDGDAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKNAEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKIACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLSDDKVTALHHSVYMREGCTSGHVVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT
Protein: Transcription factor bHLH114 (Basic helix-loop-helix protein 114) (AtbHLH114) (bHLH 114) (Transcription factor EN 65) (bHLH transcription factor bHLH114) (Q9M0X8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:16581911}.
Interaction partners:
- Myb family transcription factor PHL5
Sequence:
MTEEFEIAGISTGAWWSSPTNTAAVFSGYSLPCSTEISPDVTNFGWQNFDNKINDHNDGCMNMHNSFFEGLLIDPNDQLLPDPWSKSTIPNAKSELLENFPFLDNMFLVDSEAESLLDHEIRNHKSSKEQITQDYKNLTSKRSEELEENSDEYSPRLLKRPRLETLSPLPSFKVRKEKLGDRITALQQLVSPFGKTDTASVLNEAVEYIKFLQEQVTVLSNPEQNTIGSVQQQQCSNKKSINTQGEVEEDECSPRRYVDLSSRGLCLMPISASYPVAAAAASAAEMNVHLVSGIFHSL
Protein: Olfactory receptor 11H6 (Olfactory receptor OR14-35) (Q8NGC7)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MFFIIHSLVTSVFLTALGPQNRTMHFVTEFVLLGFHGQREMQSCFFSFILVLYLLTLLGNGAIVCAVKLDRRLHTPMYILLGNFAFLEIWYISSTVPNMLVNILSEIKTISFSGCFLQFYFFFSLGTTECFFLSVMAYDRYLAICRPLHYPSIMTGKFCIILVCVCWVGGFLCYPVPIVLISQLPFCGPNIIDHLVCDPGPLFALACISAPSTELICYTFNSMIIFGPFLSILGSYTLVIRAVLCIPSGAGRTKAFSTCGSHLMVVSLFYGTLMVMYVSPTSGNPAGMQKIITLVYTAMTPFLNPLIYSLRNKDMKDALKRVLGLTVSQN
Protein: Activin beta A subunit (Inhibin subunit beta Aa) (Inhibin, beta Aa) (Q8QGE3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Follistatin-A
- Follistatin 2
- Receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- Serine/threonine-protein kinase receptor
- Serine/threonine-protein kinase receptor
- receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- Follistatin-like 3
- Nodal-related 1.
Sequence:
MSPLPLLSGILLLLIRSCSLSAMVTKGSLPMSEQQAGATVCPSCALARFRKGVSESEDEGAQQDVVEAVKRHILNMLHLQERPNITHPVPRAALLNAIRKVHVGRVAKDGSVLIEDEASNRAETEQAEQTEIITFAETGEAPGIVNFLISKEGGEMSVVDQANVWIFLRLPKGNRTRANVNIRLLLQQGAGEKILAEKSVDTRRSGWHTFPASESVQSLLQRGGSTLSLRVSCPLCADARATPVLVSPGGSEREQSHRPFLMAVVRQMDELSLRRRRKRGLECDGKARVCCKRQFYVNFKDIGWNDWIIAPSGYHANYCEGDCASNVASITGNSLSFHSTVISHYRIRGYSPFTNIKSCCVPTRLRAMSMLYYNEEQKIVKKDIQNMIVEECGCS
Protein: Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) (P11415)
Organism: Cavia porcellus (Guinea pig)
Function: Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding.
Subcellular location: Cytoplasm.
Interaction partners:
- Sulfite oxidase, mitochondrial
- Hydroxysteroid dehydrogenase-like protein 2
- Fatty acid synthase
- EI24 autophagy associated transmembrane protein
- Hydroxyacid-oxoacid transhydrogenase, mitochondrial
- NAD
- Katanin p60 ATPase-containing subunit A-like 2
Sequence:
MATGQKLMRAIRVFEFGGPEVLKVQSDVAVPIPKDHQVLIKVHACGINPVETYIRSGTYTRIPLLPYTPGTDVAGVVESIGNDVSAFKKGDRVFTTSTISGGYAEYALASDHTVYRLPEKLDFRQGAAIGIPYFTACRALFHSARAKAGESVLVHGASGGVGLAACQIARAYGLKVLGTAGTEEGQKVVLQNGAHEVFNHRDAHYIDEIKKSIGEKGVDVIIEMLANVNLSNDLKLLSCGGRVIIVGCRGSIEINPRDTMAKESTISGVSLFSSTKEEFQQFASTIQAGMELGWVKPVIGSQYPLEKASQAHENIIHSSGTVGKTVLLM
Protein: Aconitate hydratase (Aconitase) (EC 4.2.1.3) (Q8IDR8)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Isocitrate dehydrogenase
- Citrate synthase
- Citrate synthase-like protein, putative
- Succinate--CoA ligase subunit beta, mitochondrial
- 60S ribosomal protein L11a, putative
- 50S ribosomal protein L19
- Raf kinase inhibitor
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- 40S ribosomal protein S15A, putative
- Superoxide dismutase
Sequence:
MHFRRCIRKYCINKKIVNPFEHVQRTLNEKNYYYYDINELHDSRIKSLPYSIRVLLESAVRNCDNLKVSEKNVETILGWKENCKKKKEVPFMPTRVLLQDLTGVPCIVDLATMRDTAEKLGCDAERINPLIPVDLVIDHSVQVDYSRREDALELNEKKEYERNLERFKFLKWGMNSFKNMLILPPGSGIVHQINLEYLAHCVFNKDNLLYPDSVVGTDSHTTMINGLGILGWGVGGIEAEATMLGLPISMTLPEVVGINVVGKLSDYLLSTDIVLYITSFLRKEVGVVNKYVEFFGTGLKDLKLADRATISNMAPEYGATVGFFPVDDITLEYLLQTGRDKEKVELIREYLMKNSMFNTYKDNVEYTDVYTLDLSKLNLSLSGPKRPHDNVLLSELHKDFTMCLESPIGFKGYNIAKEEREKKISFVCSKDGKEYVLSQGSVVLCAITSCTNTSNSSSMIAAGLLAKKAIEEFGLKSLPYIKSSLSPGSKTVQKYLEAGGLLKYLEQLGFYNVGYGCMTCIGNSGHLDEEVEEVINKNDLIVSSVLSGNRNFEGRVHPLIKANYLASPVLVVLFSIIGNVNVDLSNYTFNYKGKKINALDLIPRKEEIEEYESTYIKPEMYTEIYKNIKYVNKYWNDIQIKKNKLYEWDKNSTYIHKPPYFENMTLEIEKIQDIKDAHVLLFLGDSITTDHISPAGMIHKTSEAYKFLKTKNIKDQDLNTYGARRGNDEVMIRGTFANIRLINKLCPDKGPNTIHIPTNQLMSVYQAAMKYKQDNIDVIIIAGKEYGCGSSRDWAAKGPNLLGVKAVIAESYERIHRSNLIGMSVLPLQFINNQSPQYYNMDGTEKFTILLNDGNIKAQQTIKVQMNQKGKIIIFDVLCRIDTEIEERYFRNGGILKYVLRSLVNEANK
Protein: Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1) (Q2TB90)
Organism: Homo sapiens (Human)
Function: Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases. Has low glucose phosphorylating activity compared to other hexokinases. Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:30085091}. Mitochondrion membrane {ECO:0000305|PubMed:30517626}; Peripheral membrane protein {ECO:0000305}. Photoreceptor inner segment {ECO:0000250|UniProtKB:Q91W97}. Note=The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrion. {ECO:0000305|PubMed:30517626}.
Interaction partners:
- Glucose-6-phosphate isomerase
- Hexokinase-1
- Hexokinase-3
- ATP-dependent 6-phosphofructokinase, liver type
- ATP-dependent 6-phosphofructokinase, platelet type
- ATP-dependent 6-phosphofructokinase, muscle type
- Glucose-6-phosphatase catalytic subunit 1
- Glucose-6-phosphatase 3
- Glucose-6-phosphatase 2
- Phosphopentomutase
Sequence:
MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIWTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQQAQKEN
Protein: V-type proton ATPase subunit H (E9PTI1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRCSEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISASDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLRILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS
Protein: Cyp6g1 homolog a (EC 1.14.-.-) (B4LJS7)
Organism: Drosophila virilis (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004406}. Microsome membrane {ECO:0000256|ARBA:ARBA00004174}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004174}.
Interaction partners:
Sequence:
MALTEALFLIVGALSAIYLWFQRNHSYWHRKGLPFMPPSPIIGNTASVFKQESSFGMYISKVYSEPRMQDEAVVGIYVINKPALVIREPELIKSVLIKDFNRFSNRYGRCDPHGDALGSNNLFFVRNPQWKEIRTKLTPVFTSGKVKQMYPLMLEIAADLESHLARHRPAQGTEYITEVKDICARFTTDSIATIAFGVRANSLANPEAEFRNQGRKVLGASLSRSKDYFVAFFMPKLVSLLRIKFFTEEYSNFIRNTINHVMSEREGTATVRNDLIDVLVGLRKEAALDPSKPHLANNNDFLVAQAGVFFTAGFETSSSTMAFGLLELAKQPELQERLRQEINEALVEEGGKLSYEKINSLEYLAMVVDEVLRLYPVLPFLDREYQSIQGLPDLSLKPYYDYKMENGTPVFIPVYGLQRDPKYWPNPNHFDPERFSPENRKSIEPMAYQPFGLGPHNCIGSRIGLLQAKLGLVHILKNHYVRCCSQTSKDIQFDAKTFVLQLDKEMLLEIVNDRLYDEKAV
Protein: PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein) (Q96HC4)
Organism: Homo sapiens (Human)
Function: May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May be required to restrain postsynaptic growth of excitatory synapses. Isoform 1, but not isoform 2, expression favors spine thinning and elongation.
Subcellular location: Postsynaptic density {ECO:0000250|UniProtKB:Q62920}. Presynapse {ECO:0000250|UniProtKB:Q62920}. Postsynapse {ECO:0000250|UniProtKB:Q62920}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q62920}. Note=Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons. {ECO:0000250|UniProtKB:Q62920}.
Interaction partners:
Sequence:
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (K4P3M7)
Organism: bovine alphaherpesvirus 1
Interaction partners:
Sequence:
MAPPAAAPELGSCCICLDAITGAARALPCLHAFCLACIRRWLEGRPTCPLCKAPVQSLIHSVASDECFEEIPVGGGPGADGALEPDAAVIWGEDYDAGPIDLTAADGEASGAGGEAGAADGSEAGGGAGGAEEAGEARGAGAGRAAGAAGGRAGRGADAAQEFIDRVARGPRLPLLPNTPEHGPGAPYLRRVVEWVEGALVGTFAVTARELAAMTDYVMAMLAECGFDDDGLADAMEPLIGEDDAPAFVRSLLFVAARCVTVGPSHLIPQQSAPPGGRGVVFLDTSDSDSEGSEDDSWSESEESSSGLSTSDLTAIDDTETEPETDAEVESRRTRGASGAARARRPAERQYVSTRGRQTPAVQPAPRSLARRPCGRAAAVSAPPSSRSRGGRRDPRLPAAPRAAPAAQARACSPEPREEGRGAGLGVAAGETAGWGAGSEEGRGERRARLLGEAGPPRVQARRRRRTELDRAPTPAPAPAPAPAPISTVIDLTANAPARPADPAPAAAPGPASAGAQIGTPAAAAAVTAAAAAVTAAAAAPSVARSSAPSPAVTAAATSTAAAISTRAPTPSPAGRAPAADPRRAGAPALAGAARAEVGRNGNPGRERRPASAMARGDLDPGPESSAQKRRRTEMEVAAWVRESLLGTPRRSSAALAPQPGGRQGPSLAGLLGRCSGGSAWRQ
Protein: Troponin C, skeletal muscle (A0A060YT85)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Troponin T type 3a
- Troponin I, fast skeletal muscle
- Troponin I, fast skeletal muscle
- Troponin I, fast skeletal muscle
- EF-hand domain-containing protein
- Troponin I, slow skeletal muscle
- Troponin I type 1a
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- Uncharacterized protein
Sequence:
TMTDAQQEARSYLSEEMLNEFKAAFDMFDTDGGGDISTKELGQVMRMLGQNPTREELDEIIEEVDEDGSGTIDFEEFLVMMVRLLKEDQAGKSEGELAECFRVFDKNADGYIDREEFAIIIRSSGEQISEEEIDELLKDGDKNADGMLDFDEFLKMMENVQ
Protein: Arginase, mitochondrial (EC 3.5.3.1) (Agmatinase ARGAH) (EC 3.5.3.11) (Arginine amidohydrolase) (MtARGAH) (G7JFU5)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Catalyzes the hydrolysis of L-arginine to urea and L-ornithine (Probable). The latter can be utilized in the urea cycle or as a precursor for the synthesis of both polyamines and proline (Probable). Possesses agmatinase activity. Catalyzes the formation of putrescine from agmatine (By similarity).
Subcellular location: Mitochondrion {ECO:0000255}.
Interaction partners:
- ornithine decarboxylase
- ornithine decarboxylase
- Arginine decarboxylase
- ornithine carbamoyltransferase
- ornithine carbamoyltransferase
- argininosuccinate lyase
- Arginine biosynthesis bifunctional protein ArgJ
- Acetylornithine deacetylase
- N-acyl-aliphatic-L-amino acid amidohydrolase
- N-acyl-aliphatic-L-amino acid amidohydrolase
Sequence:
MSTIARRGFHYMQRLNSANVSPALLEKAQNRVIDAALTFIRERAKFKGELMRSLGGVAATSSLLGVPLGHHSSFHEGSAFAPPRIREAIWCDSTNSTTEEGKNLRDPRVITNVGDVPIEEIRDCGVDDKRLANVISESVKLVMDEDPLRPLVLGGDHSISFPVVRAVSEKLGGAVDILHFDAHPDLYHDFEGNYYSHASPFARIMEGGYARRLVQVGIRSITNDVREQVKKYGVETHEMRTLSRDRPILENLKLGEGVKGVYVSIDVDSLDPSIAPGVSHHEPGGLLFRDILNILQNLQGDIVGGDVVEYNPQRDTYDGITALVAAKLVRELAAKMSK
Protein: Hiphop (B4M926)
Organism: Drosophila virilis (Fruit fly)
Interaction partners:
Sequence:
MPPTPKSTSPTTRKRYCGLGNHHLRTPHKTISDEKILSFAKHINPELRSTTLLCGSCYDTLVKIYRVKLRHAIQLQKGKKRAAGNTNSISDVSSSQQVHSQSSSAVSAYSTTSENSSKSTISDNQPTPSNTTKRKRVEQRTPDNDDDAIDDDEEPLLSLNAVNGTRLPNIQPIPKRRQFVHLNKDVMDIYLSGTTGG
Protein: BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15) (O35152)
Organism: Rattus norvegicus (Rat)
Function: Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex.
Subcellular location: Golgi apparatus membrane; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane. Note=Present throughout the Golgi apparatus, with strongly increasing concentration from cis-Golgi to the trans-Golgi face of the stacks.
Interaction partners:
- Syntaxin-5
- Golgi SNAP receptor complex member 1
- Synaptobrevin homolog YKT6
- Golgi SNAP receptor complex member 2
- General vesicular transport factor p115
- Vesicle-trafficking protein SEC22b
- Sec1 family domain-containing protein 1
- Vesicle transport through interaction with t-SNAREs homolog 1A
- BET1 homolog
- Vesicle-associated membrane protein 7
Sequence:
MADWTRAQSSGAVEEIVDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTVARSGRDTRKLLCGMAVVLIVAFFILSYLFSRTRT
Protein: Large ribosomal subunit protein uL11m (54S ribosomal protein L19, mitochondrial) (YmL19) (P53875)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein uL1m
- Large ribosomal subunit protein uL5m
- Large ribosomal subunit protein bL36m
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL33m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein uL23m
Sequence:
MSQAAKNVIVKLIVGAGQAAPSPPVGPALGSKGIKAIDFCKEFNARSANYQPGVPVPVLITIKPDRTFTFEMKSPPTGYLLLKALKMDKGHGQPNVGTMLGSAPAKGPTRALGELSLKHVYEIAKIKKSDERHSLLEMEGIVKSIVGVAKSMGIKVVP
Protein: Putative F-box protein At3g21130 (Q9LJB9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MMKKRNTVYLSEDLIVEILSRVSAVSLARLRTTSKRWNALVKDERLAKKHSAYAPRQSLVITLIDSRVYLMNVSLQYGIEKVDLSAKLTGQFSLKDPLSNSLEEVDIRNVFHCDGLLLCSTKDNRLVVWNPCSGETRWIQPRSSYKVSDIYALGYDNTSSCHKILRMDRSEDRIPIQTEYQVYDFTSKSWLVDGVAGGLFIPSIGTRRRGLSVKGNTYWLALTEDGPPFDMFLLCFDFSTDGFRRLSLPTDTPCTYYDVSLSVTREEQQLCMFKSHGSELWIATKMESTGAISWSKSHRFHFRIDEMTVLADQEKPVFVYRFKPKSNMLHIVGEHIYIIQVDQHSADSKCPYLLTYVPSLVQIQQSI
Protein: ELAV-like protein (A0A2R8QLQ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAVRRGHIRYLKQEVYDMPNGYEDPMGDEPSDAKTNLIINYLPQNMSQEELRSLFSSIGEVESAKLIRDKMAGHSLGYGFVNYVNPSDAERAINTLNGLRLQSKTIKVSYARPSSDGIKDANLYISGLPKTMTQKNVEDMFTQYGRIINSRILVDQASGLSRGVAFIRFDKRSEAEEAIKDLNGSKPSGASEPITVKFAANPNQSKNSQLLSQLYHTQSRRFGGPVHHQPQRFRFSPMSVDHSVSSMNVASSSSSGWCIFVYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTSKCKGFGFVTMTNYEEAAMAISSLNGYRLGDKVLQVSFKSSKSHK
Protein: SR-related CTD associated factor 11 (F8VXG7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
Protein: Serine protease (Q23986)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
WVVTEAHCVVERPFDTLYSVRVGSVWKNLGGQHARVAVIREHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLADSAPAAGTEASVSGWGEIGILWLQPTSLLKTSVKILDPNVCKRSYQYITKTMISAAALLKDSCHGDTGGQL