Protein: DnaJ homolog subfamily C GRV2 (Protein GRAVITROPISM DEFECTIVE 2) (Protein GREEN FLUORESCENT SEED 2) (Protein KATAMARI2) (F4IVL6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for endosome formation, vacuolar protein sorting and determination of the embryo growth axis. Necessary for the transport of proteins into protein storage vacuoles (PSVs). Participates in vesicle trafficking from the endosome to the central vacuole. Involved in the regulation of shoot phototropism and gravitropism, probably through the positioning of specialized amyloplasts (statoliths) in endodermal cells.
Subcellular location: Endosome membrane {ECO:0000269|PubMed:17259264, ECO:0000269|PubMed:17971043}; Peripheral membrane protein {ECO:0000269|PubMed:17259264}.
Interaction partners:
- Protein SHOOT GRAVITROPISM 6
- Hyperosmolality-gated Ca2+ permeable channel 4.1
- Vacuolar protein sorting-associated protein 29
- PX domain-containing protein EREL1
- Syntaxin-22
- Protein transport protein SEC24 A
- Vesicle transport v-SNARE 11
- Vacuolar-sorting receptor 1
- ADP-ribosylation factor C1
- Chaperone protein dnaJ C76, chloroplastic
Sequence:
MDSVSRGAVASTTGGAVEEPEYLARYLVVKHSWRGRYKRILCISSGGIVTLDPNTLAVTNSYDTGSNFDGASPLVGRDENTESVGGEFTVNVRTDGKGKFKAMKFSSRCRASILTELYRLRWNQIRPVAEFQVLHLRRRNAEWVPYKLKITFVGLELVDSKSGNSRWILDFRDMGSPAIILLSDAYRTKSADSAGFVLCPMYGRKSKAFRAAPGTTNSSIVASLAKTAKSMVGVFLSVDDSQLLTVSEYMTRRAKEAVGAEETPNGWWSVTRLRSAAHGTLNMPGLSLAIGPKGGLGEHGDAVALQLILTKASLVERRIDNYEVVIVRPLSSVSSLVRFAEEPQMFAIEFSDGCPVLVYASISRDNLLAAILDTLQTEGHCPIPVLPRLTMPGHRIDPPCGRVSLISGPQHLVADLETCSLHLKHLAAAAKDAVAEGGSVPGCRARLWRRIREFNACIPYTGVPANSEVPEVTLMALITMLPSTPNLPVDAPPLPPPSPKAAATVIGFVTCLRRLLSSRSAASHIMSFPAAVNRIMGLLRNGSEGVAAEAAGLIASLIGGWSADLSTAPDSRGEKHATIMHTKSVLFAQQGYVTILVNRLKPMSVSPLFSMAIVEVFEAMVCDPHGETTQYTVFVELLRQIAALRRRLFALFAHPAESVRETIAVIMRTIAEEDAIAAESMRDAALRDGALLRHLLNAFSLPASERREVSRQLVALWADSYQPALDLLSRVLPPGLVAYLHTRPDDVVDDTDQEGSSTNRRQKRLLQQRRGRIAKGMGAQDIPLPPGNNVEAGDAAKHMSANASVPDNFQRRAADSSSEASNPQASAFPGVDSTIAGVSQNGYPAFASVTTNANGHEQPETNASDVVGSDPNLYGIQNSVLPAPAQVIVESTAVGSGKLLLNWREFWRAFGLDHNRADLIWNERTRQELIEALKAEVHNLDVEKERTEDISPGDVEATTGQEIIPRISWNYSEFSVSYRSLSKEVCVGQYYLRLLLESGNAGKAQDFPLRDPVAFFRALYHRFQCDADMGLTIDGAVPDELGSSGDWCDMSRLDGFGGGGGASVRELCARAMAIVYEQHYNTIGPFEGTAHITALIDRTNDRALRHRLLLLLKALVKVLLNVEGCVVVGGCVLAVDLLTVVHENSERTPIPLQSNLIAATAFMEPPKEWMYIDKGGAEVGPVEKDVIRSLWSKKDIDWTTKCRALGMSDWKKLRDIRELRWAVAVRVPVLTPSQVGDAALSILHSMVSAHSDLDDAGEIVTPTPRVKRILSSTRCLPHIAQALLSGEPVIVEAGAALLKDVVTRNSKAMIRLYSTGAFYFALAYPGSNLYSIAQLFSVTHVHQAFHGGEEATVSSSLPLAKRSVLGGLLPESLLYVLERSGPAAFAAGMVSDSDTPEIIWTHKMRAENLICQVLQHLGDYPQKLSQHCHSLYDYAPMPPVTYPELRDEMWCHRYYLRNLCDEIQFPNWPIVEHVEFLQSLLVMWREELTRKPMDLSEGEACKILEISLNNVSSDDLNRTASVELNEEISNISKQIQNLDEEKLKRQYRKLAMRYHPDKNPEGREKFLAVQKAYECLQATMQGLQGPQPWRLLLLLKAQCILYRRYGHVLRPFKYAGYPMLLDAVTVDKDDNNFLSNDRSPLLVAASELVSLTCAASSLNGEELVRDGGVQLLSTLLSRCMCVVQPTTSQHEPAAIIVTNVMRTLSVISQFESARAGFLELPSLIEDIVHCTELERVPAAVDAALQSIAKVSVFPELQHGLLKAGALWYILPLLLQYDSTAEESNSVESHGVGVSIQIAKNEHALQASQALSRLTGLCADESLTPYNATAADVLKALLTPKLASLLKDEVAKDLLSKLNTNLETPEIIWNSATRSELLNFVDEQRACQCPDGSYDLKNAQSFSYDALSKEVFVGNVYLKVYNDQPDSEISEPESFCNALIDFISSLVHTELPSVSEDQNLIEDRNSSNDTPELQSSVAEPSLIEEHSDHQPSSEGMKNEECFLIDHLQLGLTALQNLLTKYPDLASVFSSKERLLPLFECFSVAIASKTDIPKLCLNVLSRLTAYAPCLETMVSDGSSLLLLLQMLHSAPSFREGALHVLYALASTPELAWAAAKHGGVVYILELLLPLQKEIPLQQRAAAASLLGKLVAQPMHGPRVAITLVRFLPDGLVSIIRDGPGEAVVHALERTTETPELVWTPAMAASLSAQIATMASDIYREQQKGSVIEWDVPEQSAGQQEMRDEPQVGGIYVRRFLKDPKFPLRNPKRFLEGLLDQYLSAMAATHYEQHPVDPELPLLLSAALVSLLRVHPALADHIGHLGYVPKLVAAVAYEGRRETMSSGEVKAEEIGSDGVNESTDPSSLPGQTPQERVRLSCLRVLHQLAASTTCAEAMAATSAGNAQVVPLLMKAIGWLGGSILALETLKRVVVAGNRARDALVAQGLKVGLIEVLLGLLDWRTGGRYGLSSHMKWNESEASIGRVLAVEVLHGFATEGAHCSKVREILDASEVWSAYKDQKHDLFLPSNTQSAAGVAGFIENSSNSLTYALTAPPPPSHP