wanglab/gogpt-training-data huggingface dataset:
Protein: CMRF35-like molecule 5 (CLM-5) (CD300 antigen like family member D) (Leukocyte mono-Ig-like receptor 4) (Myeloid-associated immunoglobulin-like receptor 4) (MAIR-4) (MAIR-IV) (Q8VCH2)
Organism: Mus musculus (Mouse)
Function: Acts as an activating receptor in myeloid cells and mast cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16940041}; Single-pass type I membrane protein {ECO:0000269|PubMed:16940041}.
Interaction partners:
- High affinity immunoglobulin epsilon receptor subunit gamma
Sequence:
MWQFSALLLFFLPGCCTAQDSVTGPEEVSGQEQGSLTVQCRYSSYWKGYKKYWCRGVPQRSCDILVETDKSEQLVKKNRVSIRDNQRDFIFTVTMEDLRMSDAGIYWCGITKGGPDPMFKVNVNIDQAPKSSMMTTTATVLKSIQPSAENTGKEQVTQSKEVTQSRPHTRSLLSSIYFLLMVFVELPLLLSMLSAVLWVTRPQRCFGRGENDLVKTHSPVA
Protein: G1/S-specific cyclin-D1 (P25322)
Organism: Mus musculus (Mouse)
Function: Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also a substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner.
Subcellular location: Nucleus {ECO:0000269|PubMed:19767775}. Cytoplasm {ECO:0000250|UniProtKB:P24385}. Nucleus membrane {ECO:0000250|UniProtKB:P24385}. Note=Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members. {ECO:0000250|UniProtKB:P24385}.
Interaction partners:
- Cyclin-dependent kinase inhibitor 1B
- Cyclin-dependent kinase 4
- Cyclin-dependent kinase inhibitor 1
- Cyclin-dependent kinase 6
- Cyclin-dependent kinase 2
- Retinoblastoma-associated protein
- Cyclin-dependent kinase 1
- Cyclin-dependent kinase inhibitor 1C
- Glycogen synthase kinase-3 beta
- Cyclin-dependent kinase 4 inhibitor B
Sequence:
MEHQLLCCEVETIRRAYPDTNLLNDRVLRAMLKTEETCAPSVSYFKCVQKEIVPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQTIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTTHFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNVDPKATEEEGEVEEEAGLACTPTDVRDVDI
Protein: Trypanin-related protein, putative (Q38CZ5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPPKKEAAAAKAKGSGKGGKGKKQAPEPPLVDGKPPPDGRQLWLATDALQKAKAMRNYFQLERDRIISFWEISKKQLGELKASCRQRDRDKAEAEERHEVEKKVFKQKIRHLLYEHQLQLAEMTSEAERTLAIREEEYRQKERNAAREIHDGKLLLREQENEHREMTSALIAAHDKAIAEQQLSFERKMKEIHLMFEKKTRDLREEMDQQCREEVGLVEKRKADHIAELREMHERTFKEMKDYYSEITSNNMEMIRTLKDEVYARKRTEAHNERAMMDVAQRNRKLTEPLAKLQRQKRELEQELVNYASDKEKLKAMKAEVQQCEQELRSLSWEHEVLFQRFGKLEEDRDIILKKYNDMLQEIQQKATFRRVLIQSKLELVQTQLEGRDARLTELLRRANIDPDGISEIERRVRDLSIEKDAIIGNLQHLIGHLADKQQALVSAYEKYLKGYGITGSSSTL
Protein: PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3) (G0S0Y3)
Organism: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
Function: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03181}.
Interaction partners:
- PAN2-PAN3 deadenylation complex catalytic subunit PAN2
- Polyadenylate-binding protein
- Exonuclease domain-containing protein
- Exonuclease domain-containing protein
- RNA exonuclease 4
- Tethering factor for nuclear proteasome STS1
Sequence:
MAPLDLTRGQTDACSTENKDILCRNVLIYGHCRYEDQGCTYNHDQNKNSSQPEAPSKKMFNVDSPSFTPSGQSTVLPKKTTLSSQAASAAPFTPRGGGTPTLQTTAESTMFNPAAIREFTPQNYDLGNNNANGISQENGLYPDPFTMSTMGTALPTAGQYNLPLYGDHSGLAAPGAPFYPPHAAYPTGPIQPPHYHLYQPFGPYRQELQPWQRATYDFFMPQNLREDLQKKQFATLQVIPNSGLPQLEHWHSLVPLDTSNRKNTSCFGYPSWVYKAQNSRNGRHYALRRLEGYRLTNEKAILNVMKDWKKIKNASIVTIHEVFTTREFGDSSLIFAYDFHPLSKTLQEHHFQPIHGNRYRPPPAVPENTIWGYICQIANALKTIHSNRLAARCLEPSKIILTDINRIRLSACAILDVVQFGMNSRSVVELQQEDFVKFGKLILSLATGTLPAHLNNIPAALETLGNKYSANLKSAVNWLLDTSSGETKTIEHFMTGIASQMTTFFDLALQDNDEKLFHLAREVENGRIARSLMKLLTILERGDYDGVPSWSETGDRYQLKLFRDYVFHRVDADGKPNLSIGHMLTCMSKLEAGVDENILLTSRDNETVFVLSYRELRQMYDRAFNELVKASKTGAPGANT
Protein: Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)] (P41047)
Organism: Mus musculus (Mouse)
Function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity).
Subcellular location: [Isoform FasL]: Cell membrane {ECO:0000269|PubMed:19794494, ECO:0000269|PubMed:7532682}; Single-pass type II membrane protein {ECO:0000255}. Cytoplasmic vesicle lumen {ECO:0000250|UniProtKB:P48023}. Lysosome lumen {ECO:0000250|UniProtKB:P48023}. Note=Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination. Colocalizes with the SPPL2A protease at the cell membrane. {ECO:0000250|UniProtKB:P48023}.; SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 6, soluble form]: Secreted {ECO:0000269|PubMed:10552956, ECO:0000269|PubMed:19794494}. Note=May be released into the extracellular fluid by cleavage from the cell surface. {ECO:0000250|UniProtKB:P48023}.; SUBCELLULAR LOCATION: [FasL intracellular domain]: Nucleus {ECO:0000250|UniProtKB:P48023}. Note=The FasL ICD cytoplasmic form is translocated into the nucleus. {ECO:0000250|UniProtKB:P48023}.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 6
- FAS-associated death domain protein
- Tumor necrosis factor receptor superfamily member 10B
- Tumor necrosis factor receptor superfamily member 1A
- Caspase-8
- Tumor necrosis factor
- Perforin-1
- Tumor necrosis factor receptor superfamily, member 25
- Lumican
- Tumor necrosis factor ligand superfamily member 10
Sequence:
MQQPMNYPCPQIFWVDSSATSSWAPPGSVFPCPSCGPRGPDQRRPPPPPPPVSPLPPPSQPLPLPPLTPLKKKDHNTNLWLPVVFFMVLVALVGMGLGMYQLFHLQKELAELREFTNQSLKVSSFEKQIANPSTPSEKKEPRSVAHLTGNPHSRSIPLEWEDTYGTALISGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNQPLNHKVYMRNSKYPEDLVLMEEKRLNYCTTGQIWAHSSYLGAVFNLTSADHLYVNISQLSLINFEESKTFFGLYKL
Protein: Magnetosome protein MamM (Probable iron transporter MamM) (V6F235)
Organism: Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)
Function: Essential for magnetosome formation; required for stable accumulation of MamB. May nucleate iron crystal formation (Probable). Probably binds and transports iron. Binds divalent cations, possibly up to 3 Zn(2+) per dimer in vitro, probably iron in vivo (Probable). One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis.
Subcellular location: Magnetosome membrane {ECO:0000269|PubMed:14766587, ECO:0000269|PubMed:22007638}; Multi-pass membrane protein {ECO:0000255}. Cell inner membrane {ECO:0000305|PubMed:22007638}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes with magnetosomes in a straight line running through the center of the cell. {ECO:0000269|PubMed:22007638}.
Interaction partners:
- Magnetosome protein MamN
- Probable membrane transporter protein MamO
- Actin-like protein MamK
- Magnetosome protein MamL
- Magnetosome protein MamH
- Multi-heme protein MamP
- Magnetosome formation protease MamE
- Magnetosome protein MamQ
- Magnetosome protein MamS
- Magnetosome protein MamI
Sequence:
MRKSGCAVCSRSIGWVGLAVSTVLMVMKAFVGLIGGSQAMLADAMYSLKDMLNALMVIIGTTISSKPLDAEHPYGHGKVEFILSMVVSVVFIVLTGYLLVHAVQILLDESLHRTPHLIVLWAALVSIGVNVGMYFYSRCVAIETNSPLIKTMAKHHHGDATASGAVALGIIGAHYLNMPWIDPAVALWETIDLLLLGKVVFMDAYRGLMDHTAGEAVQNRIVEAAERVPGVRGVIHLRARYVGQDIWADMIIGVDPENTVEQAHEICEAVQAAVCGKIRRIESLHVSAEAREIGDTTKPSFSDQPLSFDEVMLSKVDN
Protein: PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL (EC 2.7.1.121) (Q9CIV7)
Organism: Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaL-ADP is converted to DhaL-ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone binds to DhaK.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MLTIDTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEVSNFGNVSEIFKKVAMTLMSKVGGASGPLYGSAFLAMSKTAIETLDTSELIYAGLEAIQKRGKAQVGEKTMVDIWSAFLNDLQTDSASKDNLEKVVKASAGLLATKGRASYLGERSIGHIDPGTQSSAYLFETLLEVVA
Protein: Protein TORNADO 1 (Protein LOPPED 1) (Q9FJ57)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the basipetal transport of auxin (IAA) that modulates growth and organs organization. Required for initial divisions in the epidermal/lateral root cap leading to the formation of epidermal cells and a clone of lateral root cap cells, as well as for the maintenance of the radial pattern of cell specification in the root, thus regulating the distinction between the lateral root cap and epidermis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- 28S ribosomal S34 protein
- 28S ribosomal S34 protein
- Protein TORNADO 2
- Tetraspanin-13
- Dipeptidyl peptidase IV-like protein
- BTB/POZ domain-containing protein DOT3
- Tetraspanin-4
- Transducin family protein / WD-40 repeat family protein
- L-type lectin-domain containing receptor kinase IV.1
- Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 13
Sequence:
MESEPDQSFKDLSWFLQAIKDPQQTFFNLQTLSFSSSGNTTHCQLITESSMNINVTRDNLTSLSQIFIELATSLETQTSLRNLEFEGIFWEIELLQSLGLLLDNTSKIKQLAFRKNRFSEQCLNELSEILKRNRFLKEVMFLESSIGYRGATLLGSALQVNDSLEELQIWEDSIGSKGAEELSRMIEMNSSLKLFSIFDSSPFTATPLISAVLGMNREMEVHMWSGDHKRDRSLKLVEFLPESKTLRIYQIDISGSCRVAAALGMNTTVRSLDMTGAKLNSRWAKEFRWVLEQNKTLREVKLSKTGLKDKAVVYIAAGLFKNKSLQSLYVDGNRFGSVGVEDLLCPLSRFSALQLQANITLRSIVFGGSNTKIGRDGLTAVLKMVTTNETVVHLGIHDDASLGPDDFIHIFKSLQKNASLRRFSLQGCKGVRGDRVLEAITETLQINPLIEEIDLARTPLQDSGKADEIYQKLGHNGRKIDEAETDDSLKDMPLTEPKSVRAFLCGQNYAGKTTLCNSILQSSSASGFPYVENVRNLMNPVEQVVKTVGGMKIKTFKDEETKISMWNLAGQHEFFALHDLMFPSPCFFLIVLSLFRKPSNKEPKTPAEVEEELEYWLRFIVSNSRKAIQQCMKPNVTIVLTHSEKINLQSESFQATVGCIQRLRDKFQALVEFYPTVFTVDARSSPSVSKLTHHIRMTSKAILQRVPRVYQLCNDIVQLLSDWRSENSNKPIMRWKAFADLCQFKVPSLRIKSRNENIQIVETRRHAIATCLHQMGEVIYFDDLGFLILDYEWFCGEVLTQLIKLDVRKQSTGERNGFVSRKELEKTLRSSLQSPIPGMTSKVLEHFDACDLVKMMKKVELCYEQDPSSPDSSLLVPSILEEGRGKTQKWQINTHDCVYSGRHLQCDDSSHMFLTAGFFPRLQVHLHNRIMELKNQHGATYSLEKYLIAITIHGINIRVELGGQLGNYIDVLACSSKSLTETLRLIHQLIIPAIQSSCRGVILLEHIIRPQCVQDLTPPRFRQSQFVSLHRLKEALSSVPAETMYDYQHTWDSVLDSGKTVLRAGFDLARNLLSDDDFREVLQRRYHDLHNLAQELQVPTDENPEADNHVPVTNELEKVDPSFGGIAKGVEAVLQRLKIIEQEIRDLKQEIQGLRYYEHRLLIQLHHKVNYLVNYNVQMDERKVPNMFYFIRAENYGRRLITSMVPGMVALRIHMLCEFRREMHVVEDQLGCDVMQIDNQAVKCLAPYMTNFMKLVTFALRIGANWAAGMGHMIPDLSHTIAHLANPAVMTGAAGAAGAIGVAAALGRNRGRDRDIQEQEQRAAQQWLIDYLREQTCSTGRDIAEKFGLWRVRYRDDGSIAWICKRHMITRAHEVIQVPL
Protein: Mitochondrial pyruvate carrier 1 (MPC1) (Q7KSC4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Mediates the uptake of pyruvate into mitochondria.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:22628558}; Multi-pass membrane protein {ECO:0000269|PubMed:22628558}.
Interaction partners:
- Mitochondrial pyruvate carrier
- Mitochondrial pyruvate carrier
- Mitochondrial pyruvate carrier
- Large ribosomal subunit protein eL8
- Transcription elongation factor SPT4
- Small nuclear ribonucleoprotein F
Sequence:
MSIRRAMSTTASKEWRDYFMSTHFWGPVANWGIPVAALADTQKSPKFISGKMTLALTLYSCIFMRFAYKVQPRNWLLFACHATNATAQSIQGLRFLHYNYGSKEQQA
Protein: Multidrug resistance protein fnx1 (Q09752)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Efflux transporter. Confers resistance to a variety of toxic compounds.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}.
Interaction partners:
- GTP-binding protein rhb1
- Vacuolar amino acid transporter 5
Sequence:
MVDQVNLATEQTSLLYPEVSRKKEELSVNKWTILPALWVGGFLSALDMTIVASLYPVIGSEFKLMNNASYIVTAYLITNTAFQPLYGRLSDIFGRRPTVVFANAAFTLGTFWCGISRSLPELCMARALAGIGGGGLGTMSSIISSDIVSLRERGTWQGITNIVWGIGGSLGGPLGGLIAQRWGWRTAFHFQVPMGILSTILVAWRVRVKPTVRNSNASLLSRIDYLGSFLLVTGITALVVTFNMGGDAFPWVSPVIITLLVSSVLILFAFYWVEKNIAVEPIAPVEILSQPTPLNVCLGNFFNAFCSFVIVYELPLFFETTLLMPSSEAGVRIFPYVISTSVGSLCSGLYMKKTGRYRNLVIAGFFFMLMGIVSFAVLTSFGHRTPLILISLCLAMTGCSYGMNLTSTLIAIISSLAPEEQAVATGLSYLFRATGSVIGISLSQTTTLSILMKQLASNLKDDPDKDDLIRRLRESISIIPNLPKDIQKLVIKSYATAFTWTFALVAIIAFAGFWCSLRIKQFYLHTSVDRS
Protein: Inositol polyphosphate-5-phosphatase F (A0A3B3IRJ9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQDLELEVKESKEKEKLERRLLEELLKMFMDSESFYYSLTYDLTNSVQRQSTGERDGRPLWQKTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLSNSAYYVAYYDDEVDKVNQYQRLSLENLEKIEIGPEPTLFGKPKFSCMRLHYRYKEASGYFHTLRAVMRNPEEDGKDTLQCIAEMLQITKQAMGSDLPIIEKKLERKSSKPHEDIIGIRSQNQGSLAQGKNFLMSKFSSLNQKVKQTKSNVNIGNLRKLGNFTKPEMKVNFLKPNLKVNLWKSDSSLETMENTGVMDKVQAESDGDMSSDNDSYHSDEFLTNSKSDEDRQLANSLESVGPIDYVLPSCGIIASAPRLGSRSQSLSSTDSSVHAPSEITVAHGSGLGKGQESPLKKSPSAGDVHILTGFAKPMDIYCHRFVQDAQNKVTHLSETRSVSQQASQERNQMTNQVSNETQSESTEQTPSRPSQLDVSLSATGPQFLSVEPAHSVASQKTPTSASSMLELETGLHVTPSPSESSSSRAVSPFAKIRSSMVQVASITQAGLTHGINFAVSKVQKSPPEPEIINQVQQNELKKMFIQCQTRIIQI
Protein: Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase) (O95819)
Organism: Homo sapiens (Human)
Function: Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14966141}.
Interaction partners:
- Striatin
- Misshapen-like kinase 1
- SH2/SH3 adapter protein NCK1
- Striatin-4
- Striatin-3
- Microtubule-associated protein RP/EB family member 2
Sequence:
MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
Protein: Soluble acetylcholine receptor (Q8WSF8)
Organism: Aplysia californica (California sea hare)
Interaction partners:
Sequence:
MLVSVYLALLVACVGQAHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRAGNGFFRNLFD
Protein: HTH-type transcriptional regulator McbR (P76114)
Organism: Escherichia coli (strain K12)
Function: Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy.
Interaction partners:
- mRNA interferase toxin MqsR
- Ribosomal protein uL3 glutamine methyltransferase
- HTH-type transcriptional repressor RspR
- Uncharacterized HTH-type transcriptional regulator YieP
Sequence:
MPGTGKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWVRMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQYNR
Protein: Pentacotripeptide-repeat region of PRORP domain-containing protein (Q580I7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLNRCYIPRAPSRRNERPNIAKLLYGKRKNALHGASKAKPTVVGMLLQVPIAELHSATRRATGMNELSNEAISEVLRKCRALNRFDRSEIVVEAVDEAKLKLTSSHYCTLMAHANDNRDSKNALRYWERACREKKANSKLHGALLATYRSSGLWKDAVRHYAAMIDDKMGCDPYALHTVMNACRRAGAVDVGLAVFSKAVQNEAAPNSTVYLELLRCMQQTRSPNRWEMSLSVLQSLGGTVDVTAGLYNATISTMAGALWEKGVEVFQAMKENNVQPSKDTLATLVSLNPNNTSHVVRCVTEAHLLGMPVTDSMYRAVLTNLTRLKLDHEAVRFAAREYSRSTEDPGNPVNSTLALGLAILDMLLAHSRPKDAMLFFNVFESQLGNIVSVSTRGLGTVGLRSQRWIVQGRVAVLDHNIILNPRFESLLSHYDSLLVPLSSIRLLVRRVKEESGTVKGSYTKHMLKRLQKLLEDHPAVRVLPLTHQLNAHTYIVDGPITPESVELLRKTVSEPKEGAHGAAFPLVIRKRGDFPNTLETLQDFSPKKGMEVAAMRGEVALHNNEPRLLKYPDRITAPERVLAVAAMLKSLNPDTSVHVLSTTSLQLQVVENWNKLRPFTGLTAVRYPDEVELKAPGEQRKQPKHPAGAVSSGLRHETDGPKPGQPGGLHMKRLFVPS
Protein: U3 small nucleolar RNA-associated protein 9 (U3 snoRNA-associated protein 9) (U three protein 9) (U3 protein 9 required for transcription) (t-UTP9) (P38882)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12068309, ECO:0000269|PubMed:15489292}. Note=Associated with ribosomal chromatin, even in the absence of transcription.
Interaction partners:
- Small ribosomal subunit protein uS17A
- rRNA processing protein RCL1
- RNA cytidine acetyltransferase
- Small ribosomal subunit protein eS7A
- U3 small nucleolar RNA-associated protein MPP10
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 13
- rRNA-processing protein FCF1
- Ribosome biogenesis protein ENP2
- Ribosomal RNA-processing protein 12
Sequence:
MGSSLDLVASFSHDSTRFAFQASVAQKNNVDIYPLNETKDYVVNSSLVSHIDYETNDMKVSDVIFFGWCSDLIDTQSSNIKRKLDEDEGTGESSEQRCENFFVNGFPDGRIVVYSSNGKDIVNIIKNKKEILGADTDESDIWILDSDKVVKKLQYNNSKPLKTFTLVDGKDDEIVHFQILHQNGTLLVCIITKQMVYIVDPSKRRPSTKYSFEISDAVACEFSSDGKYLLIANNEELIAYDLKEDSKLIQSWPVQVKTLKTLDDLIMALTTDGKINNYKIGEADKVCSIVVNEDLEIIDFTPINSKQQVLISWLNVNEPNFESISLKEIETQGYITINKNEKNNADEADQKKLEEKEEEAQPEVQHEKKETETKINKKVSKSDQVEIANILSSHLEANSTEILDDLMSGSWTEPEIKKFILTKINTVDHLSKIFLTISKSITQNPWNEENLLPLWLKWLLTLKSGELNSIKDKHTKKNCKHLKSALRSSEEILPVLLGIQGRLEMLRRQAKLREDLAQLSMQEGEDDEIEVIEHSNVISNPLQDQASPVEKLEPDSIVYANGESDEFVDASEYKD
Protein: Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform) (P04166)
Organism: Rattus norvegicus (Rat)
Function: Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:6840088}.
Interaction partners:
- NADH-cytochrome b5 reductase 3
- NADPH--cytochrome P450 reductase
- NADH-cytochrome b5 reductase-like
- NADH-cytochrome b5 reductase 2
- NADH-cytochrome b5 reductase 1
- Cytochrome P450 2B1
- Steroid 17-alpha-hydroxylase/17,20 lyase
- Mitochondrial amidoxime reducing component 2
- Acyl-CoA desaturase 1
- Cytochrome c, somatic
Sequence:
MATPEASGSGRNGQGSDPAVTYYRLEEVAKRNTAEETWMVIHGRVYDITRFLSEHPGGEEVLLEQAGADATESFEDVGHSPDAREMLKQYYIGDVHPNDLKPKDGDKDPSKNNSCQSSWAYWIVPIVGAILIGFLYRHFWADSKSS
Protein: Large ribosomal subunit protein P2v (60S acidic ribosomal protein P2-5) (Q9LUK2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays an important role in the elongation step of protein synthesis.
Interaction partners:
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein eL19z
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Large ribosomal subunit protein eL21x/eL21w
- Large ribosomal subunit protein eL21z/eL21y
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein eL29z
Sequence:
MKVVAAYLLAKLSGNENPSVADLKKIVESVGAEIDQEKIDLFFSLIKDRDVTELIAVGREKMAALSSGGGAVAVASGGGGGAAPAAEPASVESKKKEEEKEESEDDGGMMSLFD
Protein: Dynein axonemal intermediate chain 1 (Axonemal dynein intermediate chain 1) (Q9UI46)
Organism: Homo sapiens (Human)
Function: Part of the dynein complex of respiratory cilia.
Subcellular location: Dynein axonemal particle {ECO:0000269|PubMed:33263282}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:27120127}.
Interaction partners:
- Dynein axonemal heavy chain 5
- Dynein axonemal heavy chain 11
- Thioredoxin domain-containing protein 3
- Radial spoke head protein 4 homolog A
- Protein kintoun
- Radial spoke head protein 9 homolog
- Dynein axonemal assembly factor 1
- Outer dynein arm-docking complex subunit 1
- Dynein axonemal heavy chain 9
- Dynein axonemal heavy chain 7
Sequence:
MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDAELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRRQHYRDELVAGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT