wanglab/gogpt-training-data huggingface dataset:
Protein: Chitin deacetylase 2 (EC 3.5.1.41) (J9VND2)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitosan is required to anchor melanin to the cell wall, for maintenance of cell wall integrity, and for proper cytokinesis. Chitosan offers an advantage during infection as it is less readily detected than chitin by host immunosurveillance mechanisms.
Subcellular location: Secreted {ECO:0000269|PubMed:22354955}. Secreted, cell wall {ECO:0000269|PubMed:22354955}. Cell membrane {ECO:0000269|PubMed:22354955}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:22354955}. Note=GPI-anchored cell membrane protein (GPI-PMP) (PubMed:22354955). Non-covalently associated to the cell wall independently of both its GPI-anchor and beta-1,6-glucan (PubMed:22354955). Cell membrane localization is critical for effective deacetylase activity (PubMed:22354955). {ECO:0000269|PubMed:22354955}.
Interaction partners:
Sequence:
MIPSTAAALLTLTAGAAFAHTGCGGHEIGRRNVGGPMLYRRAVTDEASAAVSTDINTECTAYSYAPVTELISSFPTIWQTASIPSNDTEAQQLFGKINSTLNTKIPNDVPHGTPTGDWTGVNYSNSDPDCWWTHNKCTTPSNDTGLQADISIAPEPMTWGLGFDDGPNCSHNALYDLLLENNQKATMFFIGSNVLDWPLQAMRAHDEGHEICVHTWSHQYMTALSNEVVFAELYYTQKAIKAVLGVTPQCWRPPYGDVDNRVRMIAEGLNLTTIIWSDDTDDWAAGTNGVTEQDVTNNYQSVIDKAGNGTYTTHGPVVLNHELTNYTMSVFMTMFPKIKSAFNYIVPICTAYNITQPYAESNITCPNFETYISGVTNISSSTTQKDGSSSTNTASGSGAAGSASATSSSDDSSSSGGSSGSSGSNNASSGALGMFDSLSGVGLILGGVVAGVMLL
Protein: Elongation factor 2 (EF-2) (EC 3.6.5.-) (P29691)
Organism: Caenorhabditis elegans
Function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Involved in the morphogenesis of epidermal tissues.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P32324}.
Interaction partners:
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein uL10
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein eS6
- Large ribosomal subunit protein uL2
- Small ribosomal subunit protein uS2
- Probable elongation factor 1-gamma
- Small ribosomal subunit protein eS1
Sequence:
MVNFTVDEIRALMDRKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERCITIKSTAISLFFELEKKDLEFVKGENQFETVEVDGKKEKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLGAEELFQTFQRIVENINVIIATYGDDDGPMGPIMVDPSIGNVGFGSGLHGWAFTLKQFAEMYAGKFGVQVDKLMKNLWGDRFFDLKTKKWSSTQTDESKRGFCQFVLDPIFMVFDAVMNIKKDKTAALVEKLGIKLANDEKDLEGKPLMKVFMRKWLPAGDTMLQMIAFHLPSPVTAQKYRMEMLYEGPHDDEAAVAIKTCDPNGPLMMYISKMVPTSDKGRFYAFGRVFSGKVATGMKARIQGPNYVPGKKEDLYEKTIQRTILMMGRFIEPIEDIPSGNIAGLVGVDQYLVKGGTITTYKDAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIFEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVQSESNQICLSKSPNKHNRLHCTAQPMPDGLADDIEGGTVNARDEFKARAKILAEKYEYDVTEARKIWCFGPDGTGPNLLMDVTKGVQYLNEIKDSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHADAIHRGGGQIIPTARRVFYASVLTAEPRLLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEESQVTGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPLEAGTKPNQIVLDTRKRKGLKEGVPALDNYLDKM
Protein: Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain] (Q9JJS8)
Organism: Rattus norvegicus (Rat)
Function: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Subcellular location: Secreted.
Interaction partners:
- Mannose-binding protein C
- Plasma protease C1 inhibitor
- Mannose-binding protein A
- Complement C4
- Mannan-binding lectin serine protease 1
- Ficolin-1
- Ficolin-2
- Complement C4A
- Complement C2
- Complement C3
Sequence:
MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSLGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVLKDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKPGDFPWQVLLLGETTAAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSLIYTQAWPEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDRGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF
Protein: Tiger protein D1 (Loose aggregate C2 protein) (Loose aggregate D1 protein) (Transmembrane, IPT, Ig, E-set, Repeat protein D1) (Q9U8Q1)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May be involved in the regulation of aggregation. Activates tgrC1.
Subcellular location: Cell membrane; Single-pass type I membrane protein; Extracellular side.
Interaction partners:
- EGF-like domain-containing protein comC
- Tiger protein E1
- Tiger protein B1
Sequence:
MIHKMYFFLILLFSLFIIVYSAPNRVTRNETSIVYTYSLDSDYYTRFVMYLNATTLRTDIAPNYFDCSQIVNSERYCVFHFADSFSRLWGAVYSRVCTRTVSDPTEDCQSTWITDNAFPEPLNVKFSGYPSTSGGDVVFTGLFLRLAGGPNTLANSFTNPSKTFLIKVHGNFSDPNFNCNNFTATFPPSSGYIKVYFDDTGKSSLQLRYASPTVSSFILDESKKLVTINGDNYFTKNSLVQVFFDGIIQNNINITVNHSQIQVNNFIRVDPGPMSVNITINAVSIDNNYTYCFPAVISSISSVSNHLGGVVTIKGSKLSSTSIIPTIKIGDKQCTFIKSTTTELECQLEPNETGGKHLPVDVNFGGCNSTSSGSDAVTFTYSIPTLSSGTLSNGIVTLIGTNLGTINDSFIQLNSNGAIDNVKNDQFNISSDETTATFKLPLLKCKSFYINFTRVDISANNKPSISAPLLIYVINKPTVSNGSINIELYYIDCPISPSSTPSITVGNSSSATQCSIPSLKNLSEYYQTTCSIPYGTGTNKQFKFKYNSEESNSEFSYEPPKVESRSFSKGLFNITINGNNFGNSTSLIKVYFNGSDISSEIQSLNDNQFTFKRLNSYENGPINITVDGNSNMEPSFYLTLPPVIYSIINKENKTIGCGGLITISGKNLLTSDDKFKVRVLANNENTTVIVPDEKTLIVRANNKDSPLFVSTLIGDDLGPNTTLTYFEPRITVIPTVKNKKDGISIRVGGVSLSGIINASLGISSENVSLSCDLQCSLSPNETFYLSNPILSSNEKDITNSTDCLSCHSMNSIVVDETSGVLYLQLGPTSYHYDVKIEEIQSSLNPSSSNGGERKSSKLSGGAIAGITIGCVAGAGALVGSVFYFKLITRVKKAFN
Protein: Cystinosin, lysosomal cystine transporter (A0A669KAZ5)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MIVAAVGVTTWLQFLFCFSYIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGVFSIVFDVVFFIQHFCLYRKRPGYDQLN
Protein: Probable L,D-transpeptidase YcbB (EC 2.-.-.-) (P22525)
Organism: Escherichia coli (strain K12)
Function: Responsible, at least in part, for generating a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable L,D-transpeptidase YnhG
- Probable L,D-transpeptidase YcfS
- Probable L,D-transpeptidase ErfK/SrfK
- Probable L,D-transpeptidase YbiS
- Penicillin-binding protein 1B
- Putative L,D-transpeptidase YafK
- Peptidoglycan L,D-endopeptidase MepK
- D-alanyl-D-alanine carboxypeptidase DacC
- D-alanyl-D-alanine carboxypeptidase DacD
- D-alanyl-D-alanine carboxypeptidase DacA
Sequence:
MLLNMMCGRQLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAVSEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARDMQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGYLHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYAAMHESLLALLCDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGDDTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGLGADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNGNQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESHGYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYLHDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNIRQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR
Protein: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2) (Q9NX74)
Organism: Homo sapiens (Human)
Function: Dihydrouridine synthase. Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15994936}. Endoplasmic reticulum {ECO:0000269|PubMed:15994936}. Note=Mainly at the endoplasmic reticulum. {ECO:0000269|PubMed:15994936}.
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- tRNA
- tRNA dimethylallyltransferase
- tRNA
Sequence:
MILNSLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDDRVVFRTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKGGMGAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREERPQHPVSCEVIKAIADTLSIPVIANGGSHDHIQQYSDIEDFRQATAASSVMVARAAMWNPSIFLKEGLRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSREICEAFGLGAFYEETTQELDAQQARLSAKTSEQTGEPAEDTSGVIKMAVKFDRRAYPAQITPKMCLLEWCRREKLAQPVYETVQRPLDRLFSSIVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGRLGEESPSLHKRKREAPDQDPGGPRAQELAQPGDLCKKPFVALGSGEESPLEGW
Protein: Uncharacterized protein Rv0943c (P9WKN7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized formamidopyrimidine-DNA glycosylase-like protein
- Uncharacterized oxidoreductase Rv0945
Sequence:
MAGVSEAERRGHRKLVRFQARRAIGPIRPTSAAWDRDFDPAGKRIAVVGTDAAAAHYISRLSESAASVTVFTQAPRRVVTGVPLWTTRAKRWLRRRTGAEHPAVAWATAAIDALTSSGIRTSDGVEHPVDAIIYGTGFAIADQVGDQTLVGAGGVTIRQAWDDGMEPYLGVAVHGFPNYFFITGPDTAAQARCVVECMKLMERTASRRIEVRRSSQQVFNERAQLKPAQPHRQTGGLEAFDLSSAATEDDQTYDGAATLTLAGARFRVRVRLTGHLDPIDGNYHWQGTVFDSLPETSLTHARAATLTIGGRSAPARITEQTPWGTHSVAGVGPPPYARSGPASATT
Protein: Matrin-type domain-containing protein (Q3TMV1)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFNPQLQQQQQLQQQQQQLQQQLQQQQLQQQQQQILQLQQLLQQSPPQASLSIPVSRGLPQQSSPQQLLSLQGLLSTSLLNGPMLQRALLLQQLQGLDQFAMPPATYDGASLTMPTATLGNLRAFNVTAPSLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGVPINPSQLNHSGRNTQKQARTPSSTTPNRKDSSSQTVPLEDREDPTEGSEEATELQMDTCEDQDSLVGPDSMLSEPQVPEPEPFETLEPPAKRCRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPEHLAPQQDQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATEPQLSSHAAEAGSDPDKALPEPVSAQISEDRSREASAGGLDLGECEKRAGEMLGMWGAGSSLKVTILQSSNSRAFNTTPLTSGPRPGDSTSATPAIASTPSKQSLQFFCYICKASSSSQQEFQDHMSEAQHQQRLGEIQHSSQTCLLSLLPMPRDILEKEAEDPPPKRWCNTCQVYYVGDLIQHRRTQEHKVAKQSLRPFCTICNRYFKTPRKFVEHVKSQGHKDKAQELKTLEKETGSPDEDHFITVDAVGCFESGQEEDEDDDEEEEEEGEIEAEEEFCKQVRPRETSSEQGKGSETYNPNTAYGEDFLVPVMGYVCQICHKFYDSNSELRLSHCKSLAHFENLQKYKAKNPSPPPTRPVSRKCAINARNALTALFTSSHQPSPQDTVKMPSKVKPGSPGLPPPLRRSTRLKT
Protein: Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2) (Q804R0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor required in several developmental processes. Involved in axis formation during embryonic development by inhibiting tle3a/gro2 from binding to tcf7l1a, thereby facilitating ctnnb1-mediated transcription of canonical Wnt/CTNNB1 signaling target genes. Regulates convergent extension movements and hypaxial myogenesis during gastrulation by activating non-canonical Wnt signaling via wnt5b. Required for the formation of myofibrils and fusion of fast muscle precursor cells, potentially via transcriptional regulation of genes specific to thick and thin myofilaments. Regulates the migration of the posterior lateral line primordium during embryonic development, possibly via regulation of cxcl12a/sdf1a expression in the posterior lateral mesoderm, thereby modulating the deposition of neuromasts at correct intervals.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MTSSSKDMKAGSVLQSSGEERRRGPLDQLPPPANSNKPLTPFSIEDILNKPSVKKSVGSLCPPRVLEKVTGSSASRNGISAPSSPLCALEELASKTFKGLEVSVIQAAEGREHINAFGQRQASKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESLKKIPPQALQKLVSMEDMEDAHGGSGPISPSLSPRAFPQSPSSSRGQTTDEFSEEDEEIEVDD
Protein: Calcium-gated potassium channel MthK (O27564)
Organism: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Function: Calcium-gated potassium channel.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MVLVIEIIRKHLPRVLKVPATRILLLVLAVIIYGTAGFHFIEGESWTVSLYWTFVTIATVGYGDYSPSTPLGMYFTVTLIVLGIGTFAVAVERLLEFLINREQMKLMGLIDVAKSRHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAERYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAGDIILGIGKPEEIERLKNYISA
Protein: Small ribosomal subunit protein uS11 (40S ribosomal protein S14) (Q54EG3)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62263}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62263}.
Interaction partners:
- Large ribosomal subunit protein eL34
- Small ribosomal subunit protein eS19
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS4
- 50S ribosomal protein L20
- Small ribosomal subunit protein eS1
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein eS12
Sequence:
MSGKKEVKAPKVVEALSAKIPCGPSELVFGVAHIFASFNDTFVHVTDLSSKETIVRVTGGMKVKTDRDESSPYAATMAAQDVALRCKELGVTALHIKLRATGGNGSKTPGPGAQSALRALARSGMRIGRIEDVTPIPTDSTRRKSGHRGRRL
Protein: GH02446p (Q86NV2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
TITTVTTTTLSTESISESVTPMEPKKVAEPVPEPLKEETLVEEVVEEKPIVEVSVVDDSKTITTVTTTTTTTETISELPIPEEPKKVVELEKKPEEPKKPAYAGLPVDDSTNSWMDVLDEPMNFSDDEEEPVPEPVKEETVVQEVVEEKPIVEVSVVDDSKTITTVTTTTTNTETISELPIPEEPKKVVELEKKPEEPKKPAYAGLPVDDSTNSWMDVLDEPMNFSDDEEEPIPEPQKEESLVKEVVEEKPIVEVSVVDDSKSITTVTTTTTTTETISEIAIPEEPTKVVEPEKKPEEPKKPAYAGLPVDDSTNSWMDVLDEPMNFSDDEEEPVPEPLKEETVVEEVVEEKPIVEVSVVDDSKTITTVTTTTTTTETISELPIPEEPKKVVEPEKKPEEPKKPAYAGLPVDDSTNSWMDVLDEPMNFSDDEEEPVPEPLKEETVVEEVVEEKPIVEVSFVDDSKSITTVTTTTTTTETISELPIPEEPKKVVEPEKKPEEPKKPAYAGLPVDESSSSLMDVLDEPMNFSDDEEEPVPEPVKEETLVKEVVEEKPIVEVSVVDDSKSITTVTTTTTTTETISELPIPEEPKKVVEPEKKPEEPKKPAYAGLPVDDSSNSWMDVLDEPMNFSDDEEEPIPEPLKEETVVEEVVEIKPIVEVSVVDDSKTITTVTTTTITTETISELPISEEPKKVVEPEKKPEEPKKPAYAGLPVDDSTNSWMDVLDEPMNFSDDEEEPVPEPVKEETLVEEVVEEKPIVEVSVVDDSKTITTVTTTTTTTETISEPVISEQPKKTVEPVKKPEESTEVEPKPLSSNIWELHSSYADVLRHTVDFISLEKNNVEVPTESNLGKVPTVKEPAKLPEPLIKTKAKKEKPLKKEKGAKLLTPKDEVLPIERESAKDETKTSWSTMVENDFDDNVQTNILSADSTLWSSIVRQGAQEPITKMTQSADHDGKVLEPAFQNSQEINKFISQERSSTVIEKTKKQKSKKEKKHNKIESVVEVALEPYVDSTFMRDDPKTQQNAEIPSVLESLPIQPKSWSSIVSQTEVLPPTSIESKISQKAVDPHRSKEVQEFISKEQIFSTTVNADSKKPEDKKPLKKKKK
Protein: NAD(P)H dehydrogenase subunit H (C5MRJ2)
Organism: Oryza sativa (Rice)
Interaction partners:
Sequence:
FCDYFLRGVIEYQQLITQNPIFLERVEGVGFISGEEAVNWGLSGPMLRASGIQWDLRKVDLYESYNQFDWKVQWQKEGDSLARYLVRIGEMRESIKIIQQAVEKIPGGPYENLEVRRFKKAKNSEWNDFEYRFLGKKPSPNFELSKQELYARVEAPKGELGIYLVGDDSLFPWRWKIRPPGFINLQILPQLVKKMKLADIMTILGSIDIIMGEVDR
Protein: Protein maestro (Male-specific transcription in the developing reproductive organs) (Q7TNB4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12889070}.
Interaction partners:
- Olfactory receptor
- Olfactory receptor
Sequence:
MEQTRKIPNQPLPTPTSQSKKRRTPLLSFLSKVSWKLRLQKRELLKNALFVLAERARDPNAKKRHLAMRGLGALAREAPDKQVRKYKKVMLDLLVRGLYDPVSSEVIHESVKTLTIMLGKIQGHGLGSFFIDITLQARTLLDDEDDSVRYSAFVLFGQLASFAGWRWKKFFTQQVNQTQDSLLGHLQDESPKVAKACKMTVRACVPYLKPRKVPSFQSEEEQKNHRLSRQLSHCHPEILLFFYANKIL
Protein: Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein) (P08050)
Organism: Rattus norvegicus (Rat)
Function: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:18636092}; Multi-pass membrane protein {ECO:0000255}. Cell junction, gap junction {ECO:0000269|PubMed:15213231, ECO:0000269|PubMed:18636092, ECO:0000269|PubMed:2472402}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P23242}. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65. {ECO:0000250|UniProtKB:P23242}.
Interaction partners:
- Tight junction protein ZO-1
- Gap junction alpha-5 protein
- Proto-oncogene tyrosine-protein kinase Src
- Gap junction gamma-1 protein
- Mitogen-activated protein kinase 3
- Gap junction alpha-4 protein
- Gap junction alpha-8 protein
- E3 ubiquitin-protein ligase NEDD4
- Tubulin beta-3 chain
- Cadherin-2
Sequence:
MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVEMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGRSDPYHATTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNAKKVAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
Protein: AT-hook motif nuclear-localized protein 21 (Protein GIANT KILLER) (O82166)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs). Binds to the MARs present in the ETTIN (ETT) promoter leading to a negative regulation of its gene expression. Functions as a molecular node downstream of the homeotic protein AGAMOUS (AG), regulating patterning and differentiation of reproductive organs. Acts as a chromatin remodeling factor that modifies the architecture of ETTIN (ETT) chromatin by modulating H3 methylation leading to the regulation of ETT expression. Seems to be involved in the regulation of a set of reproductives genes including CRABS CLAW (CRC), JAGGED (JAG) and KNUCKLES (KNU).
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:19956801}.
Interaction partners:
- Protein CRABS CLAW
- Auxin response factor 3
- F25P12.91 protein
- Probable receptor-like protein kinase At1g11050
- EEIG1/EHBP1 protein amino-terminal domain protein
- At3g47680
- Downstream target of AGL15 2
- Alpha/beta-Hydrolases superfamily protein
- At5g60630
- Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MOK16
Sequence:
MAGLDLGTTSRYVHNVDGGGGGQFTTDNHHEDDGGAGGNHHHHHHNHNHHQGLDLIASNDNSGLGGGGGGGSGDLVMRRPRGRPAGSKNKPKPPVIVTRESANTLRAHILEVGSGCDVFECISTYARRRQRGICVLSGTGTVTNVSIRQPTAAGAVVTLRGTFEILSLSGSFLPPPAPPGATSLTIFLAGAQGQVVGGNVVGELMAAGPVMVMAASFTNVAYERLPLDEHEEHLQSGGGGGGGNMYSEATGGGGGLPFFNLPMSMPQIGVESWQGNHAGAGRAPF
Protein: Laccase (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase) (Diphenol oxidase) (Urishiol oxidase) (D0VWU3)
Organism: Trametes maxima (White-rot fungus) (Cerrena maxima)
Function: Lignin degradation and detoxification of lignin-derived products.
Subcellular location: Secreted {ECO:0000269|PubMed:16944230, ECO:0000269|PubMed:17012782}.
Interaction partners:
Sequence:
AVGPVADNTITDAATSPDGFSRQAVVVNGVTPGPLVAGNIGDRFQLNVIDNLTNHTMLKTTSVHWHGFFQQGTNWADGPAFINQCPISPGHSFLYDFQVPNQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPHASRYDVDNDDTVITLADWYHTAAKLGPRFPAGADATLINGKGRAPSDTSAELSVIKVTKGKRYRFRLVSLSCDPNFTFSIDGHNLTIIEVDSSNSQPLSVDSIQIFAAQRYSFVLNANQAVDNYWIRANPNFGNVGFNGGINSAILRYDGAPAVEPTTNQTTSVKPLNEVNLHPLVSTPVPGSPSSGGVDKAINMAFNFNGSNFFINGASFVPPSVPVLLQILSGAQTAQDLLPSGSVYVLPSNASIEISFPATAAAPGAPHPFHLHGHTFAVVRSAGSTVYNYSNPIFRDVVSTGTPAAGDNVTIRFLTNNPGPWFLHCHIDFHLEGGFAVVQAEDVPDVKATNPVPQAWSDLCPTYDANAPSDQ
Protein: Sr-CI (Q6V6S1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
EFFWTLAVIVIYCIGHIHGRCERSIDLDNGSINYRQRNVVRFRCNRGYTLQGTVMQTCDRDGRLRGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGAYGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGTNGFSTTTEPTAPTGSNEQPLVYDMMSCSGRCGTSISASNITNNGIVMGCGCNDECLSDETCCLNYLEECTKELLTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTTTSTTTTKRPTTTTTTTKATTTKRTTTTKKPTTTSTTPKPTTTTSTTPKSXXXTTSTTSTTSTTPTTTTTINVFTTKKTTIMIPTSSTEKTTGINTTMKTRKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLAIVLVVVLANVVNRWIIPITGSKTSSEKAVRFKKAFDSLKKQRKRNS
Protein: Formyl peptide receptor-related sequence 7 (Q71MR7)
Organism: Mus musculus (Mouse)
Function: May have an olfactory function associated with the identification of pathogens or of pathogenic states.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Heme-binding protein 1
Sequence:
MEANFSIPQNGSEVVFYDSTTSRVICIFLVVVLSITFLLGVIGNGLVIYVAGFRMTHTVTTICYLNLALSDFSYMTSLPFQITSIVMNGEWLFGWFLCKFVHMIINVNLFLSIFLITFIAMDRCICVLHPVWAQNHRTVNLARKVILGSWILVLMLIFPHFFFLTTVKDESGKVHCICNFESWAATPEEQVNMSMTVSLISVTLSFIVGFSIPMIFIVICYGLMAAKIGRRGLVNSSRPLRVLTAVAFSFFVCWFPFQLIFLLGNIGNKETQNNIDAWVNPASTLASFNSCLNPILYVFLGQQFRERLIYSLSASLERALREDSALNSDKIRNLSSQT
Protein: NADH-dependent phenylglyoxylate dehydrogenase subunit delta (EC 1.2.1.58) (Phenylglyoxylate:NAD oxidoreductase) (Phenylglyoxylate:acceptor oxidoreductase) (Q8L3B2)
Organism: Aromatoleum evansii (Azoarcus evansii)
Function: Involved in the anaerobic metabolism of phenylalanine and phenylacetate. Catalyzes the oxidative decarboxylation of phenylglyoxylate to benzoyl-CoA and CO(2). It can also react slowly with 2-oxo-3-methylbutanoate and use different electron acceptors such as benzyl viologen, methyl viologen, FAD or FMN, but NAD seems to be the physiological electron acceptor. Also catalyzes an isotope exchange between CO(2) and the carboxyl group which proves partial or complete reversibility of the oxidative decarboxylation reaction.
Interaction partners:
Sequence:
MSRHQSYPLFNLEQAGVPDDLCPVATVVSPMLPGDWRSMRPVVDRDKCVKCAVCWLYCPVQCVEEHAAWFDFNLKTCKGCGICANECPQRRSR
Protein: Protein HVA22 (Q07764)
Organism: Hordeum vulgare (Barley)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MGKSWALLTHLHSVAGPSITLLYPLYASVCAMESPSKVDDEQWLAYWILYSFITLLEMVAEPVLYWIPVWYPVKLLFVAWLALPQFKGASFIYDKVVREQLRKYRGRNRNGDADHKVHILKAEADHGRVH
Protein: Type II secretion system protein H (T2SS minor pseudopilin H) (General secretion pathway protein H) (PilD-dependent protein PddB) (Q00515)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates. Type II pseudopilus confers increased bacterial adhesive capabilities.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:8331069}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Type II secretion system protein J
- Type II secretion system protein K
- Type II secretion system protein I
- Type II secretion system core protein G
- Type II secretion system protein L
- Type II secretion system protein M
- Type II secretion system protein E
- Type II secretion system protein F
- Secretin XcpQ
- Type II secretion system protein H
Sequence:
MRASRGFTLIELMVVMVIISVLIGLAVLSTGFASTSRELDSEAERLAGLIGVLTDEAVLDNREYGLRLERDAYQVLRYDEAKARWLPVARDSHRLPEWAELTFELDGQPLVLAGSKGEKEQKKGTDQPQLLILSSGELSPFRLRLAERGPEGRALSLSSDGFRLPRVEVARR