wanglab/gogpt-training-data huggingface dataset:
Protein: Histidine rich calcium binding protein (G5E8J6)
Organism: Mus musculus (Mouse)
Interaction partners:
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
- Triadin
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
- Creatine kinase S-type, mitochondrial
- Beta-taxilin
Sequence:
MGFQGPWLHTCLLWATVAILLVPPVVTQELRGAGLGLGNWNNNAGIPGSSEDLSTEFGHHIHRGYQGEKDRGHREEGEDFSREYGHRVQDHRYPGREVGEENVSEEVFRGHVRQLHGHREHDNEDLGDSAENHLPRQRSHSHEDEDGIVSSEYHRHVPRHAHHGHGEEDDDDDGGEEEERVDVMEDSDDNEHQVHGHQSHSKERDELHHAHSHRHQGHSDDDDDDGVSTEHGHQAHRYQDHEEEDDGDSDEDSHTHRVQGREDENDDEDGDSGEYRHHTQDHQGHNEEQDDDDDDDDDDEDKEDSTEHRHQTQGHRKEEDEDESDEDDHHVSRHGRQGYEEEEDDDDDDGDDDSTEHVHQAHRHRDHEHKDDEDDSEEDYHHVPSHGRQSHQNEEEEDEAVSTEHWHQSPRHAHHDLGRESEEEVAVKYSHHVASHRPQGHNADREEDSLEEHMNEVPGHHHHRASRGDDEDISTEFGHKAPSHRLQDQDERARQGHREPVQGEIAHQPLQPTGPSSRESRKEGDHSSQEGDEDPEQRQAHSEEEKEEEEEEEEEEEEEKEGGHSLPMSQEDDEEEEKDEKESKVDRAAVSAPLSHHRKQGEEEEEEEEEEEEEILEENLLPFTIIPNPLAGREVAREGSSEEESREVTGQQDAQEYENYQPGSLCGYCSFCNRCTECESCHCDEENMGEHCDQCQHCQFCYLCPLVCDTLCTPGSYVDYFSSSLYQALADMLETPEP
Protein: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4) (P9WPX9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00110}.
Interaction partners:
- 3-dehydroquinate dehydratase
- Chorismate synthase
- Shikimate kinase
- Probable shikimate 5-dehydrogenase AroE
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Phospho-2-dehydro-3-deoxyheptonate aldolase AroG
- Prephenate dehydrogenase
- Histidinol-phosphate aminotransferase
- Prephenate dehydratase
Sequence:
MTDIGAPVTVQVAVDPPYPVVIGTGLLDELEDLLADRHKVAVVHQPGLAETAEEIRKRLAGKGVDAHRIEIPDAEAGKDLPVVGFIWEVLGRIGIGRKDALVSLGGGAATDVAGFAAATWLRGVSIVHLPTTLLGMVDAAVGGKTGINTDAGKNLVGAFHQPLAVLVDLATLQTLPRDEMICGMAEVVKAGFIADPVILDLIEADPQAALDPAGDVLPELIRRAITVKAEVVAADEKESELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELARLAGRLDDATAQRHRTILSSLGLPVSYDPDALPQLLEIMAGDKKTRAGVLRFVVLDGLAKPGRMVGPDPGLLVTAYAGVCAP
Protein: Transcriptional regulator (H9L4T0)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Interaction partners:
Sequence:
MSLPHVILTVLSTRDATGYDITKEFSASIGYFWKASHQQVYRELNKMGEQGLVTCVLEPQEGKPDRKVYSITQAGRSALGEWFDQPTAHPTVRDEFSAKLMACSVQSAEPYRLQLAELVEESRKLVAHYQEIEAAYYANPAVLDKQQRLERLTLRRNLLVRQAWIQWADEVLAELNAMA
Protein: Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase I beta) (CaM kinase IB) (CaM-KI beta) (CaMKI-beta) (Pregnancy up-regulated non-ubiquitously-expressed CaM kinase homolog) (O70150)
Organism: Rattus norvegicus (Rat)
Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro, isoform 1 and isoform 2 phosphorylate CREB1, SYN1/synapsin I. Phosphorylates and activates CAMK1.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Neuronal migration protein doublecortin
- Calmodulin-1
Sequence:
MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDAALDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGEEASRQGMTRHSHPGLGTSQSPKW
Protein: Gar1/Naf1 RNA binding region (Q587F8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Centromere/microtubule binding protein cbf5, putative
- 50S ribosomal protein L7Ae, putative
- Nucleolar protein 10
- H/ACA ribonucleoprotein complex subunit
- C2H2-type domain-containing protein
- H/ACA ribonucleoprotein complex subunit 2
- Uncharacterized protein
Sequence:
MSSRCSSRGSSCQIVEDVTVVRRRRVSLSSTDSEPFVKRVRTEASPTGASVYEADDADSISSGDGRCGGNRACPPPFVGLNDTAEPPEEAVNLYGKNGEPLYEIPLECISGVHVAVVTALFPHRPGSRVSTSTSTCGAAVAATASTGVKFHSCHGISNTTEGNIYHNSSDKNYSNNNNNNNINSNNNNNNRITNKDIESSVTTVSSGNSNNSWCMVVADSVPGIFVLDCGTRVCLPDGAVVGVVTAVMGPVNACVYAILCNGDVFSRLHASGRLEAGTGLHYDLGAQHIISNPAEQCDTTRGTDASYVNDEELPFNARPDFSDDEEERRWKMERRAKKAEGHFPPSVSDDDLSEDERVEVDWVKLAEVEDYLQGIRDAPAVHNNSFCAGNAVGNGFCPVSVRVGVEGKPPEVKQVSNTVRVVVPSWIAR
Protein: Protein myomaker (Myoblast fusion maker) (Transmembrane protein 8C) (Q6IQ69)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers. Actively participates in the membrane fusion reaction by mediating the mixing of cell membrane lipids (hemifusion) upstream of mymx (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9D1N4}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes on the cell surface of myoblasts. {ECO:0000250|UniProtKB:Q9D1N4}.
Interaction partners:
- Myogenin.
- Myoblast determination protein 1 homolog
- Myogenic factor 6
- Junctional adhesion molecule 2A
- Adhesion G protein-coupled receptor B3
- Myogenic factor.
Sequence:
MGAFIAKMLLPTISSLVFVPAASVAAKRGFHMEAMVYFFTMFFTAIYHACDGPGLSILCFMKYDILEYFSVYGTAISMWVTLLALGDFDEPKRSSLTMFGVLTAAVRIYQDRLGYGIYSGPIGTAVFMITVKWLQKMKEKKGLYPDKSVYTQQVGPGCCFGALALMLRFYFEEWDYAYVHSFYHVSLAMSFILLLPKKNRYAGTGRNAAKLNCYTLCCCV
Protein: H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) (P51796)
Organism: Rattus norvegicus (Rat)
Function: Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:P51795}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P51795}. Endosome membrane {ECO:0000250|UniProtKB:P51795}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P51795}. Cell membrane {ECO:0000250|UniProtKB:P51795}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P51795}.
Interaction partners:
- Low-density lipoprotein receptor-related protein 2
- Inositol polyphosphate 5-phosphatase OCRL
- Cubilin
- Cofilin 2
- Osteoclastogenesis associated transmembrane protein 1
- Cofilin-1
- Barttin
Sequence:
MAMWQGAMDNRGFHQGSFSSFQSSSSDEDLMDIPGTAMDFSMRDDVPPLDREIEGNKSYNGGGIGSSNRIMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSEHVTFEDRDKCPEWNSWSQLIISTDQGAFAYIVNYFMYVLWALLFAFLAVSLVKAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENHFNTSKGGELPDRPAGVGVYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHHDWGIFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPMPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPESILFN
Protein: 7-deoxyloganetic acid glucosyltransferase (EC 2.4.1.323) (UDP-glucose glucosyltransferase 8) (CrUGT8) (UDP-glycosyltransferase 709C2) (U3U992)
Organism: Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
Function: Iridoid glucosyltransferase acting exclusively on 7-deoxyloganetic acid. No activity with 7-deoxyloganetin. Catalyzes the fourth to last step in secologanin biosynthesis.
Interaction partners:
Sequence:
MGSQETNLAPHVLIFPLPIQGHVNSMLRLAELLCLAELDITFIVSEFSHSRLIKHTNVASRFARYPGFQFQPISDGLPDDHPRAGERVMDILPSTKNVTGPLFKQMMVENKCFSSATRRPITCIIADGVLSFAGDFAQEKGIPLIYFRTVSACSFWACFCMPELIESGDIPIKGNGMDLIVKSVPGMETFLRRRDLPGFCRVNDINEPKLQILKTETRQTTRAQAAILNTFEDLEGPILSQIRKHMPRLFTIGPSHSHLTSRLETKNIKTLISSGSFWEEDRSCVDWLDAQPPRSVLYVSFGSITVVTRDQLLEFWYGLVNSGQRFLWVMRPDSIMGKDGQSQIPADLEEGTKARGYMVGWAPQEEVLNHPAIGGFLTHSGWNSTLESIVAGVPMICWPYFADQMINSRFVSEIWKIGLDMKDTCDRETIVKMVRELMEIRKDEFLQRADHMAKLAKEAVSEGGSSYSNLDGLVDYIKSLII
Protein: Alpha-crystallin domain 32.1 (At1g06460) (Peroxisomal small heat shock protein Acd31.2) (Q208N7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At2g24860/F27C12.22
- Pentatricopeptide repeat-containing protein At3g04760
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 244
- At3g22970
- AFG1-like ATPase family protein
- Methionine aminopeptidase 2B
- Transmembrane protein
- 15.7 kDa heat shock protein, peroxisomal
- 2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomal
Sequence:
MEHESITARRRLAAFAAHFPATSYDSASTASLVPLNCSSSLNTVIQRCDNKISFARQASSEQGFFMRPASPDDVLENLGMNLKNTVVRRGDNRLYFARQASSAQGFFMRQASTNERTIPHDAAASTKFSATKTTGFDSSSPAYAAPHFSKPAKEDIFFPSLSPNLQKERPKLDLPKLANLGTVWSPRSNVAESTHSYVVAIELPGASINDIRVEVDNTNLTVTGRRTSICQKVDAGTKASILGYHKQEILQGPFKVSWPLPSNVNKDNVSAEFMDGILRIVIPKL
Protein: Small GTPase (Q381T2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 1-phosphatidylinositol 4-kinase
- Rab GDP dissociation inhibitor
- Exocyst complex component EXOC6/Sec15 N-terminal domain-containing protein
- Intraflagellar transport protein 56 homolog
- Geranylgeranyl transferase type-2 subunit beta
- Exocyst complex component Sec3 coiled-coil domain-containing protein
- Small GTP-binding protein RAB6, putative
- Uncharacterized protein
Sequence:
MSLKVKKLIDNKPDDERKPVKVILLGDSAVGKSKLVERFLMQRYVPVQMSTYALTLFHYDFVTEDDEAIDVDIWDTAGQERFSTMHPAYYHEAHACILVFDVTRKATYKNLEKWLGELRNYREHIPCIVACNKIDTDPSVVNKAFAFVEKHNLSLFYVSAADGTNVVQLLESAISEAVKYKKSPKKDDLMSQVLGFIKE
Protein: Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5) (P50615)
Organism: Mus musculus (Mouse)
Function: Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.
Interaction partners:
- CCR4-NOT transcription complex subunit 7
Sequence:
MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTQILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENEDENKDEISKKVSRALDKVTSDYHSGSSSSDEDTSKEVDVKPSSVAATPSPVYQISELIFPPLPMWHPLPRKKPGMYRGSGHQTHYPPPVPFAYPNPGRKNKPFRPIPVTWVPPPGMHCDRNHWINPHMLAPH
Protein: Interleukin-36 alpha (FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6) (Q9UHA7)
Organism: Homo sapiens (Human)
Function: Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1, and the production of pro-inflammatory cytokines such as TNF-alpha, IL-8 and IL-6. In cultured monocytes up-regulates expression of IL-1A, IL-1B and IL-6. In myeloid dendritic cells involved in cell maturation by up-regulating surface expression of CD83, CD86 and HLA-DR. In monocyte-derived dendritic cells facilitates dendritic cell maturation and drives T-cell proliferation. May play a role in pro-inflammatory effects in the lung.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:32272059}. Secreted {ECO:0000269|PubMed:32272059}. Note=The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. {ECO:0000269|PubMed:32272059}.
Interaction partners:
- Interleukin-1 receptor-like 2
- Interleukin-1 receptor accessory protein
- Interleukin-36 receptor antagonist protein
- Interleukin-1 alpha
- Interleukin-36 beta
Sequence:
MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
Protein: Mechanosensitive ion channel protein 3, chloroplastic (Mechanosensitive channel of small conductance-like 3) (MscS-Like protein 3) (Q8L7W1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Controls plastid size, shape, and perhaps division during normal plant development by altering ion flux in response to changes in membrane tension. Acts as a component of the chloroplast division machinery.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:16401419}; Multi-pass membrane protein {ECO:0000269|PubMed:16401419}.
Interaction partners:
- Mechanosensitive ion channel protein 10
- Mechanosensitive ion channel protein 8
- Mechanosensitive ion channel protein 4
- Mechanosensitive ion channel protein 9
- Mechanosensitive ion channel protein 7
- Mechanosensitive ion channel protein 6
- Mechanosensitive ion channel protein 5
- Protein MID1-COMPLEMENTING ACTIVITY 1
- Protein MID1-COMPLEMENTING ACTIVITY 2
- Cell division topological specificity factor homolog, chloroplastic
Sequence:
MMMRTVALPLSHDLNVHKIHEASGFHNSAAGKNRVYLTRTGLSSCATRQDVWSLQLLESLSGSIVPVSSRCNAFVCRSALSPGNGNEGPILKSTAVIFTRVYDALGGNPHLVKLIPAVGILAFATWGLRPLLRLARTTLFEKGNDANSQKSSTQYIVVSYLQPLLLWSGAILLCRTLDPIVLPSSAGQAIKQRLLIFARSISTVLAFSCCLSSLLQQVQKFFMETNNPADTRNMGFSFAGKAVYTAAWVAAASLFMELLGFSTQKWLTAGGLGTVLLTLAGREILTNFLSSIMIHATRPFVLNEWIQTKIGGYEVSGTVEQVGWWSPTIIRGDDREAVHIPNHQFSVNIVRNLTQKTHWRIKTHLAISHLDVSKINNIVADMRKVLSKNPQIEQQKIHRRVFLEDIDPENQALRILISCFVKTSRFEEYLCVKEAVLLDLLTVIRHHGARLATPIRTVQRMRNEAEVDTAGFSDIVFNQAAMNRRYMLIEPSYKINSDDNSKSPSPSPGQKSPSPGQKSEERDLQEEPSETKAETENNGSVPVSNAKKENQKAALGSNSNTGTKGSSTSTSDQPVAQKSEEKKKESVGDPHKAEKDEVSDDEATIEQTLKSKAKQGSEKNNGESKARDGGGSGTSSLLEENLVLGVALDGSKRTLPIDEEHKASGALMDSEELGIGSE
Protein: Acyl-lipid (8-3)-desaturase (EC 1.14.19.30) (AN Delta(5)-fatty-acid desaturase) (Acyl-lipid 5-desaturase) (Delta-5 desaturase) (A4KDP0)
Organism: Rebecca salina (Marine microalga) (Pavlova salina)
Function: Fatty acid desaturase that introduces a cis double bond at the 5-position in 20-carbon polyunsaturated fatty acids incorporated in a glycerolipid that contain a Delta(8) double bond.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MPPRDSYSYAAPPSAQLHEVDTPQEHDKKELVIGDRAYDVTNFVKRHPGGKIIAYQVGTDATDAYKQFHVRSAKADKMLKSLPSRPVHKGYSPRRADLIADFQEFTKQLEAEGMFEPSLPHVAYRLAEVIAMHVAGAALIWHGYTFAGIAMLGVVQGRCGWLMHEGGHYSLTGNIAFDRAIQVACYGLGCGMSGAWWRNQHNKHHATPQKLQHDVDLDTLPLVAFHERIAAKVKSPAMKAWLSMQAKLFAPVTTLLVALGWQLYLHPRHMLRTKHYDELAMLGIRYGLVGYLAANYGAGYVLACYLLYVQLGAMYIFCNFAVSHTHLPVVEPNEHATWVEYAANHTTNCSPSWWCDWWMSYLNYQIEHHLYPSMPQFRHPKIAPRVKQLFEKHGLHYDVRGYFEAMADTFANLDNVAHAPEKKMQ
Protein: C2H2-type domain-containing protein (H2KYD4)
Organism: Caenorhabditis elegans
Interaction partners:
- C-type LECtin
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein
Sequence:
MTSLIDSRVLYESDFSIFNGRLCSLRISAVTNNEEGIEKIRITSPSDATILLDTSISSDECSSFIEILKEISTARKSDPSILGPRIETIHSENEYPFQMVIEPINREKHSGKTLPLSHPPPQERCDYVLQLYAKEKVQHQSQKTKVEELTKQLQQARVDYNTLKQRCDFQEKEIALLRQITSSTGSGNRKRSRDDSETTHIKKRRCGCGDDGESCGSDCDGMDDDEEDETDTDVQMFRAATAQLQMAAAGRNTQNGTSSHQKLKRKIPKSQSVSIGNARGMVTLPNLLQPKLEESDDGYNYSGRSSTQSNIDKLELAVRRESIVDIGRAVIDGIKNKTLTENQLEEFCKTTHRPNISIFRFYKDSEECTKEENEAIMMGQTVMMKMLDPQEKAIAGVQASISSLSASFANQTKLGLIKHQRLTRSYVTLPVDYFPSIDLTEAYNSSNLFGADATMQLTNFYQTVLKNVLNPVYMIWIYTYRPSTVRTCDKHFVEFPQNVITTLFDMTTDIVGLYLPEYLLDGEIDPMDPFLLTIDAVDPFEEIMRRRTERKLANTTFNHALGRAMKNLRSYHYDPTRGILLNCSEKKNCGMHLQWEQMRKFREYCRKENVACDDATPEEMIAFNLRASKVHYEDYSPGNVSSEEGNKNEMPNFMEQLEKFSSVIVKGPNLPSTSTMSTMHIKMENGKEQSGPLLLRNSPNDQNQKVVGVVQYVICQLCPEEEQKSMDLSNQKQMEEHFLNKHVDKEKKKCEACPSDQFQPHNIGQHYRLHTNSVFACEHCGKRGRRNFLKTHIRTHTGERPYRCDTCSKSFTDASTLRRHGLVHTGEKKYQCPVCGRAIARKDNVKAHIRSHGIQI
Protein: Calcium-dependent mitochondrial ATP-magnesium/phosphate carrier protein 1 (AtAPC1) (Mitochondrial ATP-Mg/Pi carrier protein 1) (Q9FLS8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Calcium-dependent mitochondrial carrier protein that catalyzes the import of ATP co-transported with metal divalent cations across the mitochondrial inner membrane in exchange for phosphate (Pi). Can transport phosphate, AMP, ADP, ATP, adenosine 5'-phosphosulfate and, to a lesser extent, other nucleotides. Binds calcium ions Ca(2+). Mediates also calcium uptake (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:22062157}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Anaphase-promoting complex subunit 5
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Anaphase-promoting complex subunit 1
- Anaphase-promoting complex subunit 8
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase iron-sulfur protein 1, mitochondrial
- Anaphase-promoting complex subunit 13
- Anaphase-promoting complex subunit 6
- NADH dehydrogenase 1 alpha subcomplex subunit 9
- NAD
Sequence:
MEAEKSKQNPGKKPVEATMEHVLVALRETKEKREIRIQKLFEFFDNSKLGFLDDTQIEKGLSSLSIPPKYRYASDFLKVCDSNRDGRVDYQEFRRYMDAKELELYKIFQAIDIEHNGDICPAELWEALDKAGIKIKDEELASFMEHVDKDNNGIITFEEWRDFLLLNPHEATIENIYHHWERVCLIDIGEQAVIPDGISAHAQRSKLLLAGGIAGAVSRTATAPLDRLKVALQVQRTNLGVVPTIKKIWREDKLLGFFRGNGLNVAKVAPESAIKFAAYEMLKPIIGGADGDIGTSGRLLAGGLAGAVAQTAIYPMDLVKTRLQTFVSEVGTPKLWKLTKDIWIQEGPRAFYRGLCPSLIGIIPYAGIDLAAYETLKDLSRAHFLHDTAEPGPLIQLGCGMTSGALGASCVYPLQVIRTRMQADSSKTSMGQEFLKTLRGEGLKGFYRGIFPNFFKVIPSASISYLVYEAMKKNLALD
Protein: Slit1 protein (Q90Z45)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
VSELHLTVNQLESVRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQISTIAPGAFDTLQSLSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQHPDFLRQIPLQDVAFPDFRCEEGQEETSCIPRPQCPQECTCLDTVVRCSNKHLKALPRGIPKNVTELYLDGNQFTQVPGQLSTFKYLQLVDLSNNRISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFEGLRSLRLLSLHGNDISTLPEGIFADVTSLSHLAIGANPLYCSCNLRWLSSWVKTGYKEPGIARCAGPPDMEGKLLLTTPAKKFECQGPPSLIVQAKCNPCLSSPCRNQGTCHNDPLGSYRCACPIGYKGRDCEVALDGCSQNPCANGGTCQPQDGDRDGFRCLCAAGFEGPSCRTASDPCKEHSCENGGSCVAGATNYTCLCPAHYTGDFCEQPPDFCSAELSPCQHGSTCIPTSQGPRCECAPGYVGTNCSKDFDDCQDHRCQNNARCVDEVNGYSCLCAEGYSGQLCEMPPHAAGQPGLCERAECQNGAACVERGSRALCQCLPGFGGPKCEKLLSVNFVDRDTYLQFTDLQDWPRANITLQVSTAEDNGILLYNGDSDHMAVELYQGHVRVSYDPGTHPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNSGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQLLNGTSFHGCIRNLYINNELQDFTK
Protein: Phosphatidylcholine synthase (PC synthase) (PCS) (EC 2.7.8.24) (CDP-diglyceride-choline O-phosphatidyltransferase) (D0B707)
Organism: Brucella melitensis biotype 1 (strain ATCC 23456 / CCUG 17765 / NCTC 10094 / 16M)
Function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:Q9KJY8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9KJY8}.
Interaction partners:
Sequence:
MGGQKEMADSVKTKLTGKLKAKKVTAPQAKAFSVHLLTASGSFLAFLSVVAASDGRYTAMWWWLGLALFVDGIDGPIARKLEVKYVLPNWSGELLDSIIDYVTYVLIPAFALYQSGFMGTNLSFISGAIIVVSSAIYYADTGMKTKENFFKGFPVVWNMVVFTLFIVRPGEWVAFGTVVASAILSFLPINFLHPVRVVRLRPLNLTIFLLWCAFGVIALYYMLDAPLWVRIGISVTGLYIYFIGAIMQLFPSLGREAALAKARKLVEKQQKSGEAP
Protein: ATP synthase subunit a (A0PJ36)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion inner membrane {ECO:0000256|RuleBase:RU004450}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU004450}.
Interaction partners:
Sequence:
MNFDHNHVVIMGLNQRDSIWKLLNDYNVNSLKRRRQAEIDAFFELFERAQRIRFNNWQNGIELLDGAEWRNGDIVIPGGGGPVISSPLDQFFIDPLFGLDMGNFYLSFTNESLFMAVTVVLVLSLFGVVTKKGGGKSVPNAWQSLVELIYDFVLNLVNEQIGGNVKQKFFPCILVTFTFLLFCNLQGMIPFSFTVTSHFLITLALSFSIFIGITIVGFQRHGLHFFSFLLPAGVPLPLAPFLVLLELISYCFRALSLGIRLFANMMAGHSLVKILSGFAWTMLFLNNIFYFIGDLGPLFIVLALTGLELGVAILQAYVFTILICIYLNDAINLHQNE
Protein: Dymeclin (Dyggve-Melchior-Clausen syndrome protein) (Q7RTS9)
Organism: Homo sapiens (Human)
Function: Necessary for correct organization of Golgi apparatus. Involved in bone development.
Subcellular location: Cytoplasm. Golgi apparatus. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol.
Interaction partners:
- Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Sequence:
MGSNSSRIGDLPKNEYLKKLSGTESISENDPFWNQLLSFSFPAPTSSSELKLLEEATISVCRSLVENNPRTGNLGALIKVFLSRTKELKLSAECQNHIFIWQTHNALFIICCLLKVFICQMSEEELQLHFTYEEKSPGNYSSDSEDLLEELLCCLMQLITDIPLLDITYEISVEAISTMVVFLSCQLFHKEVLRQSISHKYLMRGPCLPYTSKLVKTLLYNFIRQEKPPPPGAHVFPQQSDGGGLLYGLASGVATGLWTVFTLGGVGSKAAASPELSSPLANQSLLLLLVLANLTDASDAPNPYRQAIMSFKNTQDSSPFPSSIPHAFQINFNSLYTALCEQQTSDQATLLLYTLLHQNSNIRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSNDVPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQAGAELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFTMDSD
Protein: 60S ribosomal protein L18A-1 (A8MRF3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDEEAAKPRDSTVNQQHQYYYGTFQGVANFPTPTPPPQFMQPQHPITTFPGHAYQNLQGHGGGVNYAQGFPVVVPDYTVVEVRPMIEHELPCCGLGMGWFLFIMGFLFGGIPWYLGAFIVLVTSVDHREKAGYVACSIALHQYQVVGRALPTEKDEQPKIYRMKLWATNEVLAKSKFWYYLRRQKKVKKSNGQMLAINEIFEKNPTTIKNFGIWLRYQSRTGYHNMYKEYRDTTLNGAVEQMYTEMASRHRVRFPCIQIIKTATVPASLCKRESTKQFHNSKIKFPLVFRKVRPPTRKLKTTFKANKPNLFM
Protein: L-asparaginase 1 (EC 3.5.1.1) (L-asparaginase I) (L-asparagine amidohydrolase I) (ASP I) (P38986)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm.
Interaction partners:
- Asparagine synthetase 2
- Asparagine synthetase 1
- Multifunctional protein URA2
- Argininosuccinate synthase
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase, mitochondrial
- L-asparaginase 2-1
- Adenylosuccinate synthetase
- Aspartokinase
- Glutamate decarboxylase
Sequence:
MKSDSVEITTICPDVENSQFVVQSNCPETIPEILKSQNAAVNGSGIACQQRSLPRIKILGTGGTIASKAIDSSQTAGYHVDLTIQDLLDAIPDISKVCDIEYEQLCNVDSKDINEDILYKIYKGVSESLQAFDGIVITHGTDTLSETAFFIESTIDAGDVPIVFVGSMRPSTSVSADGPMNLYQAICIASNPKSRGRGVLVSLNDQISSGYYITKTNANSLDSFNVRQGYLGNFVNNEIHYYYPPVKPQGCHKFKLRVDGKHFKLPEVCILYAHQAFPPAIVNLVADKYDGIVLATMGAGSLPEEVNETCMKLSLPIVYSKRSMDGMVPIANVPKKGSKEDNLIASGYLSPEKSRILLQLCLAGNYTLEEIKHVFTGVYGG
Protein: Thiamine-triphosphatase (EC 3.6.1.28) (F1QC87)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Thiamine pyrophosphokinase
- Nucleoside-triphosphatase, cancer-related.
- Inositol-tetrakisphosphate 1-kinase
- protein phosphatase 1, regulatory
- Inositol-tetrakisphosphate 1-kinase
Sequence:
MGILIVSWCFLYPSTKMTVEVERKFVCDAEIMRKLQDIGAECVGEREFGDQYFDSPDFLLTLKDFWLRCRDGQWELKSPAVSEAPAETLCTRYREITSLPVIQSEVSKIIRESNCSQRKQIGQTEDTPICSTGDTKWLNELGLVCFAEFRTQRCSYVLEREDGAVRVDLDRADFGYCVGEIEVLVPEGGDVNAALQSITSIAEQLGLNSEKKVKGKMDVFLQRNRPDHYNKLLSAHIL