wanglab/gogpt-training-data huggingface dataset:
Protein: RNA-binding protein, putative (Q57WC9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA-binding protein, putative
- Pumilio/PUF RNA binding protein 5, putative
- CYC2-like cyclin
Sequence:
MMSLSISRESPPCPRRHGRRSDRTQPRGPFVKLPESKLTPNECQSKTNLIVRNLSNRVDEAVLKQIFSPYGEILSAAVMRNIHTGDSLGTAFVRFATTEQARAALVGCHGRVVCGRVLSVQWAKRQHDGTPVGEARKKIVKLFIRNIPLDVGPEDVQRLFERFGTVESVSLHKDTAAATPTTDNNRPQRRIAFVTFTESGVADRAAEAVHNTRPFPSHGSVPLMVKLAEDHSERRLAAAAAVAGGGSGHNSRRRPENHQSNSTSSLTASCVGDMTPTISDAGRFSAASVHVAVPDSPEASLINNLPLPRGGVKQQSQPREAERSQLPLAAVLDISLLSCCSALAAEGLPHMSPETSSVSGSDRQWARCYVHDPYNPSRSRQYLDEK
Protein: DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein) (P23025)
Organism: Homo sapiens (Human)
Function: Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:1918083, ECO:0000269|PubMed:19197159, ECO:0000269|PubMed:20304803}.
Interaction partners:
- DNA repair endonuclease XPF
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- DNA excision repair protein ERCC-1
- General transcription and DNA repair factor IIH helicase subunit XPD
- UV excision repair protein RAD23 homolog B
- Replication protein A 32 kDa subunit
- DNA excision repair protein ERCC-5
- DNA excision repair protein ERCC-6
- DNA damage-binding protein 2
- Replication protein A 70 kDa DNA-binding subunit
Sequence:
MAAADGALPEAAALEQPAELPASVRASIERKRQRALMLRQARLAARPYSATAAAATGGMANVKAAPKIIDTGGGFILEEEEEEEQKIGKVVHQPGPVMEFDYVICEECGKEFMDSYLMNHFDLPTCDNCRDADDKHKLITKTEAKQEYLLKDCDLEKREPPLKFIVKKNPHHSQWGDMKLYLKLQIVKRSLEVWGSQEALEEAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWKRETIVHQHEYGPEENLEDDMYRKTCTMCGHELTYEKM
Protein: Voltage-dependent T-type calcium channel subunit alpha (E9Q7P2)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}.
Interaction partners:
- Voltage-dependent T-type calcium channel subunit alpha-1H
- Voltage-dependent T-type calcium channel subunit alpha
- Nitric oxide synthase 1
- Calmodulin-1
- Calmodulin-like protein 3
- Calmodulin-4
- Calmodulin 5
- Short transient receptor potential channel 5
- Short transient receptor potential channel 4
- Short transient receptor potential channel 1
Sequence:
MADSNLPPSSSAAPDPEPGITEQPGPRSPPPSPPGLEEPLDGTNPDVPHPDLAPVAFFCLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMECLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFLEENFTIQGDVALPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKEQGRECCLSKDDMYDFGAGRQDLNASGLCVNWNRYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHRLMLEQRQRYLSSSTVASYAEPGDCYEEIFQYVCHILRKAKRRALGLYQALQNRRQATGPGTPAPAKPGPHAKEPSHCKLCPRHSPLDTTPHTLVQPISAILASDPSSCPRCQHEAGRRPSGLGSTDSGQEGSGSGGSAEAEANGDGPQSSEDGVSSGLGKEEEQEDGAARLCGDVWRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQADGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTTPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSDEDQSSSNLEELDKLPEGLDSSRDLKLCPIPMTPNGHLDPSLPLGGHLGPAGAMGAAPRLSLQPDPVLVALESRKSSVMSLGRMSYDQRSLSSSRSSYYGPWGRSGTWASRRSSWNSLKHKPPSAEHESLLSGERGGSCVRACEGAREDAPPRAAPLHAPHTHHAHHGPHLAHRHRHHRRTLSLDTRDSVDLAELVPVVGAHSRAAWRAAGQAPGHEDCNGRMPNIAKDVFTKMDDRRDRGEDEEEIDYTLCFRVRKMIDVYKPDWCEVREDWSVYLFSPENKFRILCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCVAANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEMAHGLGPGPGPCPCPCPCPCPCPCPGPRMPTSSPGAPGRGSGGAGVGGDTESHLCRHCYSPAQETLWLDSVSLIIKDSLEGELTIIDNLSGSIFHHYSSPAGCDKCHHDKQEVQLAETEAFSLNSDRSSSVLLGDDLSLEDPTACPQGPKESKGELEPPEPMQAGDLDECFFPFAGEPVSAGPESLLCEMGAIPFNPVQSWLKHESNQAPPSPFSPDGSSPLLQMPAEFFHPAVSASQKGQEPGMSSGTLPKIALQGSWASLRSPSVNCTLLRQATVSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPVQVPGPRASLSPATRRRLSLRGRGLFSLRGLRAHQRSHSSGGSTSPGCTYHDSMDPSDEEGRGGAGGGGAGSEHSETLSSLSLTSLFCLPPTLPPPGLTPARKFSSTSSLAAGPGRPGATVSVRGLARSPSWAADRSKDPPGQAQLASGFGSSAPEPQPPPGESTDAASKRKR
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Q9D9S8)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004434}.
Interaction partners:
Sequence:
MAGWRLSLCARSLSAIRRLQAAPLCWKSSSSRAVVARSAAARKEQEEPTVQWMEDPDPEDENVYLKNPHFHGYDDDPKVDALNMHAVFFFGFSIALVLGTTFVAYVPNYKMIEWARREAAMLVKHREASGLPIMESNYFDPTKINLLEDD
Protein: Probable indole-3-pyruvate monooxygenase YUCCA10 (EC 1.14.13.168) (Flavin-containing monooxygenase YUCCA10) (Q9FVQ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in auxin biosynthesis.
Interaction partners:
- Tryptophan aminotransferase-related protein 1
- L-tryptophan--pyruvate aminotransferase 1
- Tryptophan aminotransferase-related protein 2
- Aromatic aminotransferase ISS1
- Nuclear transcription factor Y subunit B-9
- DUF7650 domain-containing protein
- Amidase 1
- B3 domain-containing transcription factor LEC2
- Auxin transporter protein 1
- E3 ubiquitin-protein ligase ORTHRUS 3
Sequence:
METVVVIVGAGPAGLATSVCLNQHSIPNVILEKEDIYASLWKKRAYDRLKLHLAKEFCQLPFMPHGREVPTFMSKELFVNYLDAYVARFDINPRYNRTVKSSTFDESNNKWRVVAENTVTGETEVYWSEFLVVATGENGDGNIPMVEGIDTFGGEIMHSSEYKSGRDFKDKNVLVVGGGNSGMEISFDLCNFGANTTILIRTPRHVVTKEVIHLGMTLLKYAPVAMVDTLVTTMAKILYGDLSKYGLFRPKQGPFATKLFTGKAPVIDVGTVEKIRDGEIQVINGGIGSINGKTLTFENGHKQDFDAIVFATGYKSSVCNWLEDYEYVMKKDGFPKAPMPKHWKGEKNLYCAGFSRKGIAGGAEDAMSVADDIRSILATLKNN
Protein: TBC1 domain family member 5 homolog B (Q54TA5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May act as a GTPase-activating protein for Rab family protein(s).
Interaction partners:
- Vacuolar protein sorting-associated protein 29
Sequence:
MDTSGFLDLDINSGTTTPNIRNSVTTSNDIMSSIFDTIPTKEKKVDAAVESIFGTEAANSPLISSSIPPIPIEASTSTQQQQQQQQQQEEIIPSQPISVTKENTVTTTTTTTATTAVPTTTTTPTSTLINSEPIVVNPLEVNINTKVDDSDSDQDEQIKKENVVHEIFTPIVSIINNNNNNNNNEIDNNNNGNSNENTTTTTTNKDMNNSFSMGVTTASKDEHIISTTTVGTIEQEIHEKQEEPLISPLQSEFNKIFFSTIPLEKKPLEILKMNAFTGALKYSPLRGIAWKLFLGGLDINRVDKWERDITQQRKRYEKLKEEHCFDPRNSNSTYDPLSQNDDSPWNKFFKNLDTQKIIKIDLERTHPDNDFFSNPVIREMMATILFVYSKTNGIISYRQGMHELLAPIIYLYNQEYSSYKKLDENSSSTLVDFIYNIKYLEHDTFAIFERLMKFTSDWYAPAPTQQTNNSNNSNNTNNNNTTTSPSSSSSSSSSSTTTAAATTVSSSTSTSSSSSTITSSSSSTVSPPPPSSSSSPSPPPPPPLGSNSPTVASSSSSSVQDNEEEELSSKCNDVVLKCKYIHSILLKQKDFELYQHLDSLDIEPQIYLLRWIRLLFGREFHFDDVLNIWDALFAYGENLILIDYFCISMLTYIREHLLKSDSIYALKRIYKYPPVEDVYMLIKKALEIKDSNCSIAGMVKTAQPPTTLSSSGSRQIPNNNNNNNNNNNNNNNNNNNNNNSNNNINNNNNNSNNNITTPSTQANTLPFPETSTFESTTSSFQPYSSQLSSANTTPIDPLSNKTTPLISSTSNVSNTPNITSTSTLLSSSSSSSSSTTTPLQSHTPILTHNNNNSHFSPSPSSSSSSLNNSSHVSIPVKSNVKDIFANSKESDLFSLFSTATTPINNNTSSLSISNPTISIGQARTLNKHKSMTLPSSPLISQDSEALKQLKNTQIEFGNQLKEVLPFLEKGKNFLLGNEDELSKSEIDDFIKALEKVKQIQEILSNNNINNNNENKL
Protein: Interleukin-2 (IL-2) (Q13169)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU363134}.
Interaction partners:
Sequence:
MYRMQLLSCIALILALVTNSAPTSSSTKKTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKQLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
Protein: Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (A2THE9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU365061}. Chromosome, telomere {ECO:0000256|RuleBase:RU365061}.
Interaction partners:
Sequence:
MSGQYSTDGGFRPVLEILRSLYPVVQTLEEFTDGLQFPDGRKPVLLEETDGARFKKLLSGLIVCAYTPPQLRVPAQLSTLPEVLAFTLNHIKRKKLRNVLGFGYQCSDVTTSSDPFRFHGDVSQTAASISTSEVWKRINQRLGTEVTRYLLQDCAVFTTVPPSCVLQVCGEPVYDLLMPRSWSGFFLSNSDNERISGAMRKFPAVQKTVAISKKRTRDNEKYISVKRRRVKETVNNNNGNYRSLCFAISKKRAIDNEENISLKRRRMEETDQVAKIRNENHESQSFAISKKRARDNEENISLKRQRMEEIDQVAKIRNENHGSQSWKPADQRPPRPSQCSIRVLSMLYNGRGMKNFLLNRKLKGVGGARRMQGEDLVRMIFLQSESNDSKPKKLPKRFFAMVPLFSRLLRQHRKCPYRLFLQRKCAGNPDVKDMESLLKSHSSPYRVYLFVRECLRHIIPHELWGCQENQLHFLSNVKNFLLLGKFERLTLVQLMWRMKVQACHWLGPKKRQCASEHRYREWMLGQCMGWMLSGFVVGLVRAQFYITESMGHKHTLRFYRGDVWSRLQDQAFRAHLCKGQWRPLSPSQALKVPNSAVTSRIRFIPKTSSMRPITRLSGSRDTLQYFQSCVRVLQNVLSVCVREAPGPMGSTVWGWQDIHRRLQDFSPQQKSSPRPLYFVKVDVSGAYDSLPHLKLVEVLKEVLGPFAEQSFFLRQYSSVWSDPTRGLRKRFCTKAEMSEPLNMKGFVVDEQVSGRLHDAILVERHSSEVRGGDVFQFFQKMLCSYVIHYDQQMFRQVCGIPQGSSVSSLLCNLCYGHMEKALLKDIAKGGCLMRLIDDFLLITPHLSKATEFLTTLLSGVPDYGCQINPQKVAVNFPVCVSWVNSGVSVLPSSCLFPWCGLMIHTHTLDVYKDYSRYDGLSLRYSLTLGSAHSPSTVMKKLLSVLSIKSTDIFLDLRLNSVEAVYRSLYKLILLQALRFHACVRSLPLGQSVNRNPSFFLKMIWRMTRVTNKLLTHINKGLPVCSVDSGGVLQSEAVQLLFCLAFETLFRRFRSVYHCLIPALHKRKRALQRELCGITLARVRQASSPRIPLDFSMRV
Protein: Protein LIFEGUARD 1 (AtLFG1) (F4JIE8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: (Microbial infection) Facilitates the development of the powdery mildew fungus E.cruciferarum.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Heat shock 70 kDa protein 17
- Protein DETOXIFICATION 49
- Subtilisin-like protease SBT1.9
- AAA-ATPase ASD, mitochondrial
- Bax inhibitor 1
- Endoplasmin homolog
- RING-H2 finger protein ATL66
- Putative NAC domain-containing protein 94
- Acireductone dioxygenase 3-requiring) 3)
- Serine/threonine-protein kinase/endoribonuclease IRE1b
Sequence:
MAKSDIETGGGNELYPGMKESSELRWAFIRKLYSILSLQLLVTVGVSAVVYFVRPIPEFITETHRGLAVFFVILLLPLLLLWPLLAFEKKHPINCIVLSIFTLSISFSVGICCSLSQGRIVLEAAILTAVMVFGLTIYTFWAVKRGHDFSFLGPFLFGALLIILVFTLLQIFHPLGKLSSMIFSGIASIVFCGYIIFDTNQLIKKLNYDEYITAAIRLYLDVMNLFLSLLGIISN
Protein: Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog) (D3ZTQ1)
Organism: Rattus norvegicus (Rat)
Function: Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors (By similarity). Represses the splicing of MAPT/Tau exon 10.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MYGAGGGRAKAERKGGVKEEAGPGGTGTGGNRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSAYDAEYATWNRDYQLSEEEARVEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTYGSDYYDPSEPTEEEEPSKQREKSEAENLEENEEPFIAPLGLSVPSDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAESKSEEKKKSGPTSDNEEEDDEEDGSYLHPSLFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQADSSAPAPPTADGTPAQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVATYYSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAESSSGVTSTTTTTSALAPVAIIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGGSTQAASTAEEAPTETAVEESSEAGEDGAPEGMAETGGRGSGKKEAGSSKSTVDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSEEDEESRECQESTSSVANPSPAAAPPSAVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPDAEVGKLEESTFGVEETGVMPCPLLVGGRTLPMLEGKPPERPSSRCRDPPREEEREKKKKKHKKRSRTRSRSPKYHSSSKPRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREDRSVPTAYRMSGSPGVSRKRTRSRSPHEKKKKRRSRSRTKAKARSQSTSPSKQAAQRPSAHSAHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS
Protein: Probable prefoldin subunit 6 (P52554)
Organism: Caenorhabditis elegans
Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Required for positioning of the mitotic spindle.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18062952}.
Interaction partners:
- Probable prefoldin subunit 3
- Probable prefoldin subunit 4
- Prefoldin subunit 2
- Probable prefoldin subunit 5
- Probable prefoldin subunit 1
- Spindle and kinetochore-associated protein 2
- EGF-like domain-containing protein
- EGF-like domain-containing protein
- EGF-like domain-containing protein
- T-complex protein 1 subunit alpha
Sequence:
MADMAKFEEEVNKLRTLEKDREKYFTSRQEMEMRLTESKNVKAELDLMESDSKVYKLIGAVLVRQDLEEARSTVEKRLEFIDSETKRVEASISDISKKCTEQRDKVMNMQKSFQMMAQAAAQAQKK
Protein: Small ribosomal subunit protein eS7z (40S ribosomal protein S7-1) (Q9C514)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS12y
- Small ribosomal subunit protein eS19z
- Large ribosomal subunit protein eL27x
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein eS24z
- Small ribosomal subunit protein eS24y
- Small ribosomal subunit protein eS1z
- U3 small nucleolar ribonucleoprotein protein IMP3
- Small ribosomal subunit protein uS2z
Sequence:
MFSAQHKIHKEKGVELSELDEQVAQAFFDLENTNQELKSELKDLYVNSAVQVDISGGRKAIVVNVPYRLRKAYRKIHVRLVRELEKKFSGKDVILIATRRIVRPPKKGSAAKRPRNRTLTSVHEAILDDVVLPAEIVGKRTRYRLDGTKIMKVFLDPKERNNTEYKVEAFSAVYKKLTGKDVVFEFPITEA
Protein: 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (EC 2.3.1.51) (EC 2.3.1.n4) (Lysophosphatidic acid acyltransferase) (LPAAT) (Phosphatidic acid synthase) (PA synthase) (P26647)
Organism: Escherichia coli (strain K12)
Function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:1557036}; Peripheral membrane protein {ECO:0000269|PubMed:1557036}.
Interaction partners:
- Glycerol-3-phosphate acyltransferase
- Probable glycerol-3-phosphate acyltransferase
- Phosphatidate cytidylyltransferase
- Diacylglycerol kinase
- Phosphate acyltransferase
- Glycerol-3-phosphate dehydrogenase [NAD
- Uncharacterized protein YnbB
- CDP-diacylglycerol pyrophosphatase
- Aerobic glycerol-3-phosphate dehydrogenase
- Anaerobic glycerol-3-phosphate dehydrogenase subunit A
Sequence:
MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPTDAESYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQKIAELDKEVAEREAAGKV
Protein: Cyclic dof factor 2 (Dof zinc finger protein DOF5.2) (AtDOF5.2) (Q93ZL5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The stability of CDF2 is controlled by 'GIGANTEA' and redundantly by ADO3, ADO2 and/or ADO1.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Adagio protein 3
- RNA binding / RNA-directed DNA polymerase
- non-specific serine/threonine protein kinase
- Zinc finger CCCH domain-containing protein 67
Sequence:
MADPAIKLFGKTIPLPELGVVDSSSSYTGFLTETQIPVRLSDSCTGDDDDEEMGDSGLGREEGDDVGDGGGESETDKKEEKDSECQEESLRNESNDVTTTTSGITEKTETTKAAKTNEESGGTACSQEGKLKKPDKILPCPRCNSMETKFCYYNNYNVNQPRHFCKKCQRYWTAGGTMRNVPVGAGRRKNKSPASHYNRHVSITSAEAMQKVARTDLQHPNGANLLTFGSDSVLCESMASGLNLVEKSLLKTQTVLQEPNEGLKITVPLNQTNEEAGTVSPLPKVPCFPGPPPTWPYAWNGVSWTILPFYPPPAYWSCPGVSPGAWNSFTWMPQPNSPSGSNPNSPTLGKHSRDENAAEPGTAFDETESLGREKSKPERCLWVPKTLRIDDPEEAAKSSIWETLGIKKDENADTFGAFRSSTKEKSSLSEGRLPGRRPELQANPAALSRSANFHESS
Protein: DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (Q61881)
Organism: Mus musculus (Mouse)
Function: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Uncomplexed form does not show ATPase or DNA helicase. Required for S-phase checkpoint activation upon UV-induced damage (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q91876}. Chromosome {ECO:0000250|UniProtKB:Q91876}. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. {ECO:0000250|UniProtKB:Q91876}.
Interaction partners:
- DNA replication factor Cdt1
- DNA replication licensing factor MCM6
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM5
- DNA replication licensing factor MCM2
- Cell division control protein 45 homolog
- Cell division control protein 6 homolog
- DNA replication licensing factor MCM3
- DNA replication complex GINS protein PSF1
- DNA replication complex GINS protein SLD5
Sequence:
MALKDYAIEKEKVKKFLQEFYYENELGKKQFKYGTQLVHLAHREQVALYVDLDDIAEDDPELVDSICENAKRYSRLFGDVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNPQNQYPSELMRRFELYFRGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHWIVKMTKSDDDVSGAGELSSEELKQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPQGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNVQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPAQFEPLDMKLMRRYIAMCHERQPTVPESLADYITAAYVEMRREARASKDATYTSARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMSKDSLLGEKGQTARTQRPADVIFATIRELVSRGRSVHFSEAEQRCISRGFTPAQFQAALDEYEELNVWQVNTSRTRITFV
Protein: Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4) (Q96C45)
Organism: Homo sapiens (Human)
Function: May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
Interaction partners:
- Suppressor of fused homolog
Sequence:
MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITNWVRLTREIKHKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQESSVEDLSLSRNTMECSGPQDSKELLQNSQSRQAKGHKSGQPLGHSFRLENPTEFRPKSTLEGQLNESMFLLSSRPTPRTSTAVEVSPGEDMTHCSPQKTSPLTKITSGHLSQQDLESQMRELIYTDSDLVVTPIIDNPKIMKQPPVKFDAKILHLPTYSVDKLLFLKDQDWNDFLQQVCSQIDSTEKSMGASRAKLNLLCYLCVVAGHQEVATRLLHSPLFQLLIQHLRIAPNWDIRAKVAHVIGLLASHTAELQENTPVVEAIVLLTELIRENFRNSKLKQCLLPTLGELIYLVATQEEKKKNPRECWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQSQGFITGEIGPILWYLFRHSTADSLRITAVSALCRITRHSPTAFQNVIEKVGLNSVINSLASAICKVQQYMLTLFAAMLSCGIHLQRLIQEKGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREMLLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLVTSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVEWRLFSLRLLSETTSLLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIFEVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIVRLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQKLLLRILRRMITSNEKHLESLKNAGSLLRALERLAPGSGSFADSAVAPLALEILQAVGH
Protein: Neurolysin, mitochondrial (EC 3.4.24.16) (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase) (Q9BYT8)
Organism: Homo sapiens (Human)
Function: Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity). Acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By similarity).
Subcellular location: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:P42676}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P42676}.
Interaction partners:
- Neurotensin/neuromedin N
- Angiotensin-converting enzyme
- Kininogen-1
Sequence:
MIARCLLAVRSLRRVGGSRILLRMTLGREVMSPLQAMSSYTVAGRNVLRWDLSPEQIKTRTEELIVQTKQVYDAVGMLGIEEVTYENCLQALADVEVKYIVERTMLDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIVHLQETCDLGKIKPEARRYLEKSIKMGKRNGLHLPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKECKDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVDQSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDMFYSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLHNFLKREPNQKAFLMSRGLHAP
Protein: Type II secretion system protein E (T2SS protein E) (EC 7.4.2.8) (General secretion pathway protein E) (Type II traffic warden ATPase) (P31742)
Organism: Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Function: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:Q00512}. Note=Membrane association is not an intrinsic property but requires the XpsL/GspL gene product. {ECO:0000250|UniProtKB:Q00512}.
Interaction partners:
- Type II secretion system protein L
- Type II secretion system protein F
- General secretion pathway protein F
- General secretory pathway related protein
- Fimbrial assembly protein
- Secretin XpsD
- Type II secretion system protein E
- Type II secretion system core protein G
- Prepilin leader peptidase/N-methyltransferase
- Type II secretion system protein I
Sequence:
MEQRSAETRIVEALLERRRLKDTDLVRARQLQAESGMGLLALLGRLGLVSERDHAETCAEVLGLPLVDARQLGDTPPEMLPEVQGLSLRFLKQFHLCPVGERDGRLDLWIADPYDDYAIDAVRLATGLPLLLQVGLRSEIDDLIERWYGQGRSAMGTIVETADGDASSTDDIEALRDLASEAPVIRLVNLVIQHAVELRASDIHIEPFESRLKVRYRVDGVLVEGESPPAKLTAAVISRIKIMAKLNIAERRLPQDGRIMLRVQGKELDLRVSTVPTAHGESVVMRLLDRETVVFDFYKLGFTEDFLPQFRKVLEQPHGIMLVTGPTGSGKTTTLYTALSQLNTSDVKIITVEDPVEYQIEGINQIQAKPQIGLDFANALRSIVRQDPDIIMIGEMRDLETARIAIQSALTGHLVLSTLHTNNAAGGITRLLDMGVEDYLLTSTINGILAQRLVRKLDLANAERYAASPEEIERFDLRRLQPDGEIFLYRPRATAAAPTGYLGRTTIVEFLVMNDELRRAVMRRAGMGEIEQLARKSGMRTMYEDGLSKALRGETTIEEVLRVTEDA