wanglab/gogpt-training-data huggingface dataset:
Protein: Phosphatidylinositol transfer protein beta isoform (PI-TP-beta) (PtdIns transfer protein beta) (PtdInsTP beta) (P53811)
Organism: Mus musculus (Mouse)
Function: Catalyzes the transfer of phosphatidylinositol, phosphatidylcholine and sphingomyelin between membranes (By similarity). Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function (By similarity).
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:7654206}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P53812}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P53812}.
Interaction partners:
- Membrane-associated phosphatidylinositol transfer protein 3
Sequence:
MVLIKEFRVVLPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYENDGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVHIDIADRSQVEPADYKADEDPALFHSVKTKRGPLGPNWKKELANTPDCPRMCAYKLVTIKFKWWGLQSKVENFIQKQEKRIFTNLHRQLFCWIDKWIDLTMEDIRRMEDETQKELETMRKKGSVRGTSAADA
Protein: Putative endoplasmic reticulum mannosidase MNL2 (EC 3.2.1.-) (Mannosidase-like protein 2) (Q12205)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Putative mannosidase involved in glycoprotein quality control since it is involved in the targeting of misfolded glycoproteins for ER-associated protein degradation (ERAD).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21971548}; Single-pass type II membrane protein {ECO:0000269|PubMed:21971548}.
Interaction partners:
- Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
- ER degradation-enhancing alpha-mannosidase-like protein 1
- Initiation-specific alpha-1,6-mannosyltransferase
- Protein RER1
- Alpha-1,2-mannosyltransferase ALG9
- Mannosyl-oligosaccharide glucosidase
Sequence:
MSIARLVYSLFRRVRSVLLLFITISLLFYYTFQNEIDILNSYALNDSLPSINNYEHNTEGSSKLDPPDLSSTGSDRIATDKENGNVAVDLSDPATLREKNKYFPLLLKGSSHQIGSNLPISSLLTYKEKYPVLFEYSSPSLTSISQNDVHKIQPAMQLPPDVDMIKQIKDIFMKSWNQEQLLLKSNLRRESTWPIDLIDSLDTLYLCGETKLFQDSVNIIEDFDFRVPPLAMEVIDIPDITTRVLEGLLSAYELSMDKRLLNKAKHVADFILRSFDTPNRIPILKYFWKSDLRNRFPDRTVPSGQLTTMALAFIRLSQLTRLNKYFDAVERVFTTIRQSYNEFDMEFMLPDVVDASGCQLLTQEEIENGAHLKGSSIMKSINENFKFVHCQQLGKFLNPPIDDNSLQEQSQYQAYRINEKTVPILENLFKINDLFQSSYDILDGSSKNANAATMDPSIGSEVEAVDEIIEKRNFKDGTKKDSTKNTVGDKSLIDSQTFLTNSISNIFKFMTFRPMLPKQTENKKFNFLNSILTKSQFMPTTNELDVTIRKSYDVSLYSCRLGGILGLSSRVPHRGGVNTKYILPSSLLEMSEIITESCFMLMEEFDGLLPQKFELDPCTDETNGNCEFNGETKSRMIANGEYETFENDLDVGIKVSNYGKGGNDQKAKRNVLSKDGITETQNIKGDTVGSSKSIAEIDGDEVTQIRRVFTLGKDIKPHITTDDTMGSQWKNHPDWPFWVNKVESRRLLDSNIIESIFYMYRISGEQKWRSMGKQSFGILMQELMELNSGAKGLWQIKEFYENGEKVNNDLPSYWFSRTLKYYLLLFSDGDKVSLDKHILTQGGHIIKKK
Protein: UDP-galactose/UDP-glucose transporter 1 (At-UDP-Glc/GalT) (AtUTr1) (O64503)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential sugar transporter required for the transport of UDP-galactose and UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum, to ensure quality control of protein folding. Essential for pollen development and involved in embryo sac progress.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16467298, ECO:0000269|PubMed:19906043}; Multi-pass membrane protein {ECO:0000269|PubMed:16467298, ECO:0000269|PubMed:19906043}.
Interaction partners:
- Calnexin homolog 1
- GDP-fucose transporter 1
- NADH kinase
- NAD
- NAD kinase 2, chloroplastic
- soluble epoxide hydrolase
- GDP-mannose transporter GONST3
- Uncharacterized GPI-anchored protein At5g19250
- UDP-xylose transporter 2
- Protein disulfide isomerase-like 1-2
Sequence:
MEVHGSGFRRILLLALCISGIWSAYIYQGVLQETLSTKRFGPDEKRFEHLAFLNLAQSVVCLIWSYIMIKLWSNAGNGGAPWWTYWSAGITNTIGPAMGIEALKYISYPAQVLAKSSKMIPVMLMGTLVYGIRYTFPEYMCTFLVAGGVSIFALLKTSSKTISKLAHPNAPLGYALCSLNLAFDGFTNATQDSIASRYPKTEAWDIMLGMNLWGTIYNMIYMFGLPQGIGFKAIQFCKLHPEAAWDILKYCICGAVGQNFIFMTISNFGSLANTTITTTRKFVSIVVSSVMSGNPLSLKQWGCVSMVFGGLAYQIYLKWKKLQRVEKKKQKS
Protein: Calmodulin-like protein 6 (Q9ZR02)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potential calcium sensor.
Interaction partners:
- Probable calcium-binding protein CML48
- At2g03740
- Probable calcium-binding protein CML49
- Probable calcium-binding protein CML50
- GDSL esterase/lipase EXL6
- Probable calcium-binding protein CML22
Sequence:
MDSTELNRVFQMFDKDGDGKITTKELNESFKNLGIIIPEDELTQIIQKIDVNGDGCVDIEEFGELYKTIMVEDEDEVGEEDMKEAFNVFDRNGDGFITVDELKAVLSSLGLKQGKTLEECRKMIMQVDVDGDGRVNYMEFRQMMKKGRFFSSLS
Protein: Uncharacterized protein YceK (P0AB31)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized lipoprotein YfgH
- Acidic protein MsyB
Sequence:
MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDSAWRYVTILDLPFSLVFDTLLLPIDIHHGPYE
Protein: V-type proton ATPase subunit e 1 (V-ATPase subunit e 1) (D-serine-regulated transcript 1 protein) (DSR-1) (V-ATPase 9.2 kDa membrane accessory protein) (V-ATPase M9.2 subunit) (Vacuolar proton pump subunit e 1) (Q794C0)
Organism: Rattus norvegicus (Rat)
Function: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase subunit H
- V-type proton ATPase subunit D
- V-type proton ATPase subunit C 1
- V-type proton ATPase subunit S1
- V-type proton ATPase subunit F
- V-type proton ATPase subunit E 1
- V-type proton ATPase 116 kDa subunit a 1
- V-type proton ATPase subunit B, brain isoform
- V-type proton ATPase 16 kDa proteolipid subunit c
Sequence:
MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP
Protein: Eukaryotic translation initiation factor 4E nuclear import factor 1 (Eukaryotic translation initiation factor 4E transporter) (Q5BL27)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MEKDENGENLVDPIKDSVMTSAYRYTKEELMEIKELPISNERPECLSEKYDSDGVWDPEKWHASLYPSSESSCPTEGYKKDYVDDRVPLKRRIADPRERVKDDDLEVVLSPQRRSFGGGCQVAQTALPRRPTSPLENKENESLRLGGARRIGSGRIMASRVFERDARVDKERERDRERDFKDKRFRRDFGDKRVFSERRRNDSYAEEEPEWFSGGPTSQSETIELIGFDDKILEDDKRRTKRSKKRPESVKEVECNGGLSDGPEVVRESGADQEVPHAELPEQTPGDFDFNEFFNLEKTMPGLASPQQQSVDPVLVSLTEAQVPAPQQKNIFQELLVTPHGPVPVPGLIHHRASPPLFPQRSQMQDFFPGMSPATGFHGGPQTVLDQIPDLHRARNTQPMRALPMGVDQTNLEALFQQDLAVLNRPQYQQAYNKQAHDKMFRNRPTRMNRSPVPHLPGRTSPGSTVTSVLSPSFTPTSVIKKMYESKEKSRDDLGSRPGSKEETVNSHNSQDDGPPSPSSFLEDVDTSGPQTGGVKACSTPVPTQNRHIKDPERPRPPSVTGPHTPTMLSPGPSSPFPRPQMYPVPLLPHVPLVRPPPQLHPGVMQRMLAQGIQAQQLGPTLLQTGMFPQAVDLSQLQGLPPALLGQPLYPLSPAGHPLMAPRAAGTHVQLAVMQQQLQQQQRPNLHVAPSGGPQSQSHGPHRTNQRRGASPPLGLAKWFGSDMLQQPLPSMPSTKVISVDELEFRQ
Protein: Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (P29410)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Subcellular location: Mitochondrion intermembrane space {ECO:0000255|HAMAP-Rule:MF_03168}.
Interaction partners:
- Adenosine kinase
- Adenine phosphoribosyltransferase
- Adenylosuccinate lyase
- Nucleoside-triphosphatase, cancer-related
- Adenylate kinase isoenzyme 5
- Adenylate kinase 9
- Pyruvate kinase PKLR
- Adenylate kinase 7
- Adenylate kinase 8
- Pyruvate kinase PKM
Sequence:
MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV
Protein: Transcription factor TIP2 (Basic helix-loop-helix protein 142) (OsbHLH142) (Basic helix-loop-helix protein TIP2) (TDR INTERACTING PROTEIN2) (Q5JNS0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor that binds to the E-box-containing promoter regions of the transcription factors TDR and EAT1, activating their expression. May have a role in specifying the cell pattern of the inner anther walls and functioning in meiosis progression. Required for male reproduction. Acts downstream of UDT1 and GAMYB, but upstream of TDR1 and EAT1 in pollen development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:24755456}.
Interaction partners:
- PHD finger protein PERSISTENT TAPETAL CELL 1
Sequence:
MYHPQCELLMPLESLEMDVGQSHLAAAVAAAMPGELNFHLLHSLDAAAAAASSTAASASSQPTVDYFFGGADQQPPPPAAMQYDQLAAPHHHQTVAMLRDYYGGHYPPAAAAAAATEAYFRGGPRTAGSSSLVFGPADDESAFMVGPFESSPTPRSGGGRKRSRATAGFHGGGPANGVEKKEKQRRLRLTEKYNALMLLIPNRTKEDRATVISDAIEYIQELGRTVEELTLLVEKKRRRREMQGDVVDAATSSVVAGMDQAAESSEGEVMAAAAMGAVAPPPRQAPIRSTYIQRRSKETFVDVRIVEDDVNIKLTKRRRDGCLAAASRALDDLRLDLVHLSGGKIGDCHIYMFNTKIHSGSPVFASAVASRLIEVVDEY
Protein: Elongation factor 1-alpha 4 (EF-1-alpha 4) (eEF-1A4) (Q8GTY0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21245040}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:21245040}.
Interaction partners:
- Probable elongation factor 1-gamma 2
- Adenylyl-sulfate kinase 4, chloroplastic
- Adenylyl-sulfate kinase 1, chloroplastic
- Adenylyl-sulfate kinase 2, chloroplastic
- Adenylyl-sulfate kinase 3
- Elongation factor 1-delta 1
- Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic
- Actin-2
- Small ribosomal subunit protein eS1z
- Large ribosomal subunit protein uL18y
Sequence:
MGKEKFHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKAERERGITIDIALWKFETTKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTTGGFEAGISKDGQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYDEIIKEVSSYLKKVGYNPDKIPFVPISGFEGDNMIERSTNLDWYKGPTLLEALDQINEPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGMIKPGMVVTFAPTGLTTEVKSVEMHHESLLEALPGDNVGFNVKNVAVKDLKRGYVASNSKDDPAKGAANFTSQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFSEILTKIDRRSGKEIEKEPKFLKNGDAGMVKMTPTKPMVVETFSEYPPLGRFAVRDMRQTVAVGVIKSVDKKDPTGAKVTKAAVKKGAK
Protein: Cup2p (Q5AKX6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Cu
Sequence:
MLIKGVKYACERCIRGHRVTTCTHSNEPLTMIKPKGRPVTQCQHCRENRKSKNLHVTCSCGKKGKNGSHLPSCACHKTNHCTCSTNMTKKTTTKGDIHHMTASEKAKKKSLIDAANAGLKKRSDSVSTTQSAASSSASPSSAASPNKKSSVPPPGPTNSQQKKQQSTSPNQSRQTTQPAYNNLSDQNFVIEDIVFPFNTDNGLFDMFSSNATSEVGGAGSGTRDSQIATSNLASDNSTPFNSNYDTGISYSNKDVGLPLSPNETEADPMFPLFPLVGTQSFDRENQPLSALSNEKEPPQPQQPTPVRPSHNVSTAMNNISSNSYSSIPSAVEVSSINHQQSRPKRPESVLSIASNSSTRSFDFFGNNHTNYNSSFMNGSLPTSFTSAAFPPSNGFDENSLSNLNPDDHNNMQHHFGRTGLGAVKFGSQLSKIESEMYTDNFFDDPYAPQSQNVDQLQFPDTTTIPNLYNVTEFNPSDNYASSNPSNYDVNNNSDVITNGGNNHRNNNNNNDTIYPSYSNENKITINDNSININGNTVGNENHPNITSTSSVQLPGNSEIPNLYNVQDILSDSAFDDFIPTLTDNTKDQNNI
Protein: 5-aminovalerate aminotransferase DavT (EC 2.6.1.48) (5-aminovalerate transaminase) (Delta-aminovalerate aminotransferase) (Q88RB9)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Function: Catalyzes the conversion of 5-aminovalerate to 5-oxopentanoate.
Interaction partners:
- Glutarate-semialdehyde dehydrogenase
- 5-aminopentanamidase
- Succinate-semialdehyde dehydrogenase
- NAD+-dependent succinate semialdehyde dehydrogenase
- Medium chain aldehyde dehydrogenase
- Aminotransferase, class III
- Gamma-aminobutyraldehyde dehydrogenase
- NAD+-dependent succinate semialdehyde dehydrogenase
- 4-guanidinobutyraldehyde dehydrogenase
- Agmatinase
Sequence:
MSKTNESLMQRRVAAVPRGVGQIHPIFVDTAKNSTVIDVEGRELIDFAGGIAVLNTGHLHPKVVAAVQEQLTKVSHTCFQVLAYEPYVELCEKINKLVPGDFDKKTLLVTTGSEAVENAVKIARAATGRAGVIAFTGGYHGRTMMTLGLTGKVVPYSAGMGLMPGGIFRALFPSELHGISVDDAIASVERIFKNDAEPRDIAAIILEPVQGEGGFLPAPKELMKRLRALCDQHGILLIADEVQTGAGRTGTFFAMEQMGVAPDLTTFAKSIAGGFPLAGVCGKAEYMDAIAPGGLGGTYAGSPIACAAALAVIEVFEEEKLLDRSKAVGERLTAGLREIQKKYPIIGDVRGLGSMIAVEVFEKGTHTPNAAAVGQVVAKAREKGLILLSCGTYGNVLRILVPLTAEDALLDKGLAIIEECFAEIA
Protein: Ribonucleoprotein p18, mitochondrial, putative (Q57ZP0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ATP synthase subunit beta
- ATP synthase alpha chain
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Transmembrane protein
- Uncharacterized protein
- ATP synthase delta chain
- Uncharacterized protein
- ATP synthase F1 subunit gamma protein, putative
Sequence:
MMRRVYAPVFCSVAAARFAATSAAKKYDLFGYEVDTNTAPWIEKIKKCKYYDEAGEVLVNMNVSNCPPDIATYNATLQCIYQSPSKQSTPVDNESKFCAMMDLLEEMQHRNRLKPNEESWTWVMKECVKSGQFRLGYCIQQVMETECKGCPADLVKANEANAQKAKTEGKEHPGHLSQQAGLFDVKVE
Protein: dUTP diphosphatase (EC 3.6.1.23) (B4LTG5)
Organism: Drosophila virilis (Fruit fly)
Interaction partners:
- Ribonucleoside-diphosphate reductase
- Thymidylate synthase
- Sulfotransferase domain-containing protein
- Trifunctional purine biosynthetic protein adenosine-3
- protein xylosyltransferase
- Replication factor C subunit 3
- Proliferating cell nuclear antigen
- Proliferating cell nuclear antigen
- Uncharacterized protein
- Probable deoxycytidylate deaminase
Sequence:
MASPVIDDIQTAKKMKLDKKCVLRYAKIIEHALEPQRGSERAAGFDLRSAYDLIVPARGKAIVKTDLQVQVPEGSYGRVAPRSGLAVKNFIDVGAGVVDEDYRGNLGVVLFNHSDTDFEVKRGDRIAQFICERISIPELEQVDKLDDTVRGESGFGSTGVKELPGDKQQIVTAKTPTDKKCVLRFAKLTEHALEPQRGSEKAAGLDLRSAYDLKVPSRGKAIVKTDLQVQLPEGSYGRVAPRSGLAVKNFIDVGAGVVDEDYRGNLGVVLFNHSDTDFEVKRGDRIAQFICERIFYPELEQEDKLDDTERGEAGFGSTGVKELPGDKQQIVTAKTPTDKKCVLRFAKLTEHALEPQRGSEKAAGLDLRSAYDLIVPAHGKAIVKTDLQVQLPEGSYGRVAPRSGLAVKNFIDVGAGVVDEDYRGNLGVVLFNHSDTDFEVKRGDRIAQFICELIFYPEPKEEDKLDDTERGEAGFGSTGVKELPEAKLAKQQNGNGKTPLGENDATPIST
Protein: Probable phosphoglycerate mutase PMU1 (EC 5.4.-.-) (Phosphomutase homolog 1) (P36069)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable phosphomutase that may have a function related to the manipulation of phosphate groups on carbohydrates. Reduces trehalose-6-phosphate levels when overexpressed in TPS2-deleted cells. Reduces 5'-Phosphoribosyl-4-carboxamide-5-aminoimidazole (AICAR) levels, a metabolic intermediate at the crossroads between AMP and histidine biosynthesis pathways, when overexpressed in a ADE3-ADE16-ADE17 triple deletant.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Putative uncharacterized protein YBR013C
Sequence:
MSLRAVPGYFAAYPSEGFQGLDSTKYDHLELINHKNWKELYHAIPRNTKNRHYKLLILARHGQGYHNAAILRYGMEKWDAYWSLLSGDEHGEWLDSKLTPLGKDQVRRTGSNVLLPMAKQLGMLPHVFFSSPMRRCLETFIESWTPVLAETQELPAGTKISTRIIEGLRETLGSHTCDKRVAHSMAVDEYQDFSTESGHTVHWQYVPDYPEDDELWLPDHRETCAEMDKRTLNGLFELFNQLSSEEKFISLTCHSGVIQSVLRNLQHPPIYNLDTGKVVAVVVEVPVNTADRGRL
Protein: Four and a half LIM domains (Q7T327)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MASRSNCFYCREDLSGKKFVRKDEKQVCVRCFDKFCANTCTECRRTISTDSKELHHKGKYWHSDCFRCAKCYKNLAKESFTSKDDRILCGTCSSREDAPRCHGCYKPILPGTENVEYKGNSWHDECFKCYQCQKPIGNKSFITKNNNVYCSPCHEKKFAKQCACCKKPITTGGVNYQDQPWHSECFVCSSCRKPLAGTRFTSHEEKVYCVDCYKSTVAKKCSGCQNPITGFGKATNVVNYEGGSWHDYCFNCKKCSLNLADKRFVAHSGHIYCSDCSKKL
Protein: Superoxide dismutase [Fe] (EC 1.15.1.1) (P9WGE7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular location: Secreted {ECO:0000269|PubMed:1904126, ECO:0000269|PubMed:9933629}.
Interaction partners:
- Superoxide dismutase
- Catalase-peroxidase
- Large ribosomal subunit protein bL17
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL15
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL3
- Alkyl hydroperoxide reductase C
- Aconitate hydratase A
- Protein RecA
Sequence:
MAEYTLPDLDWDYGALEPHISGQINELHHSKHHATYVKGANDAVAKLEEARAKEDHSAILLNEKNLAFNLAGHVNHTIWWKNLSPNGGDKPTGELAAAIADAFGSFDKFRAQFHAAATTVQGSGWAALGWDTLGNKLLIFQVYDHQTNFPLGIVPLLLLDMWEHAFYLQYKNVKVDFAKAFWNVVNWADVQSRYAAATSQTKGLIFG
Protein: Zinc finger protein 330 (Nucleolar autoantigen 36) (D6RBR7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MPKKKTGARKKAENRREREKQLRASRSTIDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMS
Protein: ETS translocation variant 2 (Ets-related protein 71) (O00321)
Organism: Homo sapiens (Human)
Function: Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Subcellular location: Nucleus.
Interaction partners:
- Endothelial transcription factor GATA-2
Sequence:
MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTATAETCWKGTSSSLASFPQLDWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIPAAGSEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ
Protein: Signal recognition particle protein (SRP) (EC 3.6.5.4) (Fifty-four homolog) (P9WGD7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity). Most of the substrate proteins are involved in stress regulation, lipid metabolism, intermediary metabolism, and cell wall processes. Shows GTPase activity.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00306}. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane. {ECO:0000255|HAMAP-Rule:MF_00306}.
Interaction partners:
- Signal recognition particle receptor FtsY
- Protein translocase subunit SecA 1
- Protein translocase subunit SecY
- Sec translocon accessory complex subunit YajC
- Protein translocase subunit SecE
- Protein translocase subunit SecA 2
- Probable protein-export membrane protein SecG
- Membrane protein insertase YidC
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS5
Sequence:
MFESLSDRLTAALQGLRGKGRLTDADIDATTREIRLALLEADVSLPVVRAFIHRIKERARGAEVSSALNPAQQVVKIVNEELISILGGETRELAFAKTPPTVVMLAGLQGSGKTTLAGKLAARLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFAPHPGASPESGPGDPVAVAAAGLAEARAKHFDVVIVDTAGRLGIDEELMAQAAAIRDAINPDEVLFVLDAMIGQDAVTTAAAFGEGVGFTGVALTKLDGDARGGAALSVREVTGVPILFASTGEKLEDFDVFHPDRMASRILGMGDVLSLIEQAEQVFDAQQAEEAAAKIGAGELTLEDFLEQMLAVRKMGPIGNLLGMLPGAAQMKDALAEVDDKQLDRVQAIIRGMTPQERADPKIINASRRLRIANGSGVTVSEVNQLVERFFEARKMMSSMLGGMGIPGIGRKSATRKSKGAKGKSGKKSKKGTRGPTPPKVKSPFGVPGMPGLAGLPGGLPDLSQMPKGLDELPPGLADFDLSKLKFPGKK
Protein: LD28763p (PDGF- and VEGF-related factor 1, isoform A) (VEGF2-A ligand long isoform) (Q9VWP6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- PDGF- and VEGF-receptor related, isoform J
- Latrophilin Cirl
- Epidermal growth factor receptor
- PDGF- and VEGF-related factor 2
- FI06402p
- Furin-like protease 1, isoforms 1/1-X/2
- Signal transducer and transcription activator
- Ras-like protein 1
- Tie-like receptor tyrosine kinase
Sequence:
MAMSRIRILKPMQHPLLILPVLLLVLIVSEAAAGSLVSPNNRQPSQRFFYAAATSSSSTQTKVRLLRQADDPSAAPGALEGSCCQGAAAEAGTPLTLPLSVSAELTNVTADYDVSGEMPSSKENFKRSIMKSTVRNATPASCSPQPTIVELKPPAEDEANYYYMPACTRISRCNGCCGSTLISCQPTEVEQVQLRVRKVDRAATSGRRPFTIITVEQHTQCRCDCRTKAEDCNVYQSYRKDLCRCECHNTDARDKCLEQAENKYWVDDNCTCVCRYNQSCTTGTVFDETQCKCTDPAAPIDVLDRKRFIVQAVQVDPDNTTLYSV
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (Q8QGU2)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Ryanodine receptor 2.
- Uncharacterized protein.
- Calmodulin, striated muscle
- Calmodulin
- Protein phospatase 3 regulatory subunit B alpha isoform type 1
- Serine/threonine-protein kinase TOR
- TGF-beta receptor type-1
- Uncharacterized protein
Sequence:
MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFRFKIGRQEVIKGFEEGVTQMSLGQRAKLTCTPEMAYGATGHPGVIPPNATLLFDVELLRLE
Protein: Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (MRF-1) (Microglia response factor) (P55009)
Organism: Rattus norvegicus (Rat)
Function: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play an role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O70200}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:O70200}; Peripheral membrane protein {ECO:0000250|UniProtKB:O70200}; Cytoplasmic side {ECO:0000250|UniProtKB:O70200}. Cell projection, phagocytic cup {ECO:0000250|UniProtKB:O70200}. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. {ECO:0000250|UniProtKB:O70200}.
Interaction partners:
- TYRO protein tyrosine kinase-binding protein
- Glial fibrillary acidic protein
- Interleukin-1 beta
- RNA binding protein fox-1 homolog 3
- Macrosialin
- Integrin alpha-D
- CX3C chemokine receptor 1
- Tumor necrosis factor
- T-lymphocyte activation antigen CD86
- Interleukin-6
Sequence:
MSQSKDLQGGKAFGLLKAQQEERLDGINKHFLDDPKYSSDEDLQSKLEAFKTKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMYEEKNKEHQKPTGPPAKKAISELP
Protein: Endonuclease IV (EC 3.1.21.9) (Deoxyribonuclease IV) (P39250)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Cleaves single-stranded DNA in a dC-specific manner. The cleavage occurs exclusively at the 5'-proximal position (dC1) within a dCs tract having a minimal size of 6 bases. These specific cleavages may have a detrimental effect on the replication of host dC-containing DNA.
Interaction partners:
Sequence:
MQKTNPGLQRLFQIPTFTLSNSDLTCEMKVKIADTARYSLKQNPNQDKAEVIERCRIAVYAEFFVADWLSGYVNKGQEDVDDPYTYAWDVLAHPKYCGLRVEVKTHQTDSRWISVTTGCSGEYPYGSGINLGPILNHQVADCIIIFNTKEIHPGVIQYTPKFIGDREDLRKVVRKSNYNGWYLSI