wanglab/gogpt-training-data huggingface dataset:
Protein: Nucleoprotein (Protein N) (Nucleocapsid protein) (P22677)
Organism: Bovine respiratory syncytial virus (strain A51908) (BRS)
Function: Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases (Probable). RNA replication depends on the availability of soluble nucleoprotein (By similarity). The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication (By similarity). Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway. May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs (By similarity).
Subcellular location: Virion {ECO:0000250|UniProtKB:P03418}. Host cytoplasm {ECO:0000269|PubMed:32878896}. Note=Localizes in cytoplasmic inclusion bodies. {ECO:0000269|PubMed:32878896}.
Interaction partners:
Sequence:
MALSKVKLNDTFNKDQLLSTSKYTIQRSTGDNIDIPNYDVQKHLNKLCGMLLITEDANHKFTGLIGILYAMSRLGREDTLKILKDAGYQVRANGVDVITHRQDVNGKEMKFEVLTLVSLTSEVQGNIEIESRKSYKKMLKEMGEVAPEYRHDSPDCGMIVLCVAALVITKLAAGDRSGLTAVIRRANNVLRNEMKRYKGLIPKDIANSFYEVIEKYPHYIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTTEELEAIKNQLNPKDNDVEL
Protein: Microsomal signal peptidase 12 kDa subunit (Q582V5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MAGAKEVQSVHPFTRWVAGLSSPMSLTDQRAAATRISHLMLTTVFVATVCGYFVGNVHTAFFAVAAACGVSLIVWGPNWYQNEDPDQRWCDENEVKKYYETLEQLRDEAKQKIIDEFESKGEKKRN
Protein: Rifin (Q8IJ00)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKLHFPKILLFFFPSNILLTSYHVHSKNKPHTTPHHTPTTTTRVLSECDIRSSIYDNDAEMKSVKETFDRQTSQRFEEYEERMKGKRQKRKEERDKNIQEIIEKDRMDKSLAEKVEKGCLKCGCGLGGVAASIGIFGTIAVNEWTKAATATATQKGIEAGINVVIDTLKNLFHIDGVTDLKWKTLITAQNYTDKSLVDGVIRELARTLCRGSEDTAGGFCLFTDKANTLTQAINGHVPKAISKGTAEFVTVTEAEIGNVTTTGGAYFTGIIVSVVVIVVIVLVMIIIYLVLRNRRKTKMTKKLQYMKLLKE
Protein: Elongation factor 2b (EF-2) (EC 3.6.5.-) (Q6P3J5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P13639}. Nucleus {ECO:0000250|UniProtKB:P13639}.
Interaction partners:
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- FAU ubiquitin-like and ribosomal protein S30 fusion b
- Elongation factor 1-gamma
- Ribosomal protein L3
- Ribosomal protein L4
- 40S ribosomal protein S6
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS2
- Ribosomal protein S3
Sequence:
MVNFTVDQIRAIMDKKSNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASARAGETRFTDTRKDEQERCITIKSTAISMYYELTENDLAFIKQCKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEDEGGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGEAQLSPADRCKKVEDMMKKLWGDRYFDPAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDTEDKDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPGDDEAAMGIKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFDQAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSAESDQMCLSKSPNKHNRLYMKARPFPDGLAEDIDKGDVSSRQELKTRARYLADKYEWEVTEARKIWCFGPDGTGPNMLVDVTKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHTDAIHRGGGQIIPTARRVLYACQLTAEPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVMGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPKDAASKPCQIVADTRKRKGLKEGIPALDNFLDKL
Protein: Inositol polyphosphate-5-phosphatase B (B1ARF3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRYPSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGSAGGGKLGWGAGPGAAVRPALGWAGSAVWPVDARGEDQSPGGPLEAGTLGQKFCDVLLRRA
Protein: Complement C8 alpha chain (A0A8I5ZRH5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MFTVAFFGLSLMAWHSGVTAQEKVNQRVTRAVTPGAVACQLSDWSEWTDCFPCQNEKYRYRSLLQPSKFGGTICSGDIWDKANCDSPTPCLRQAQCGQDFQCRETGRCLKRHLVCNGDQDCLDGSDEDNCDDARVIEDDCRQYEPIPGSERAALGYNILTQEEGQSVYDAKYYGGQCETVYNGDWRRLQYDPTCERLYYGEDEKYFRKPYNFLKYHFEALADTLISSEFYDDANDLFSKIQRDKSQSNSVTFGISPAKSPITLDASVSWSDESSFMKELSKYNEKKYSFMRVSTKVQTAHFKMRRHNIVLDEGMMESLMELPEQFNYGMYSKFINDYGTHYITSGTMGGIYEYVLVLDKEKMRIHGITVEDVKKCIGGGVGLQFGEKIIGEGDLSGESCVMTGDGNQDKRKKDLAVEDIISRVQGGSSRWSTGLAHNSSAITYRSWGRSLKYNPVVIDFEMQPIYQLLQHTNLGPLETKRRNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCSCQCSMGRQGPACESMVLEAMEGAKADGRWSCWSSWSECRGGSRERRRQCNNPAPQNGDQQGGDF
Protein: BUD13 homolog (Q9BRD0)
Organism: Homo sapiens (Human)
Function: Involved in pre-mRNA splicing as component of the activated spliceosome.
Subcellular location: Nucleus {ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:29361316}.
Interaction partners:
- Smad nuclear-interacting protein 1
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- Microfibrillar-associated protein 1
- RNA-binding motif protein, X-linked 2
- Splicing factor 3B subunit 2
- Pre-mRNA-splicing factor CWC22 homolog
- Splicing factor 3A subunit 2
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
- Splicing factor 3B subunit 1
- Cell division cycle 5-like protein
Sequence:
MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKWSVEDM
Protein: RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) (P52756)
Organism: Homo sapiens (Human)
Function: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Subcellular location: Nucleus {ECO:0000269|PubMed:18851835}.
Interaction partners:
- ATP-dependent RNA helicase DHX15
- RNA-binding protein 25
- RNA-binding protein 39
- Cell division cycle and apoptosis regulator protein 1
- Splicing factor U2AF 65 kDa subunit
- ATP-dependent RNA helicase A
- Serine/arginine repetitive matrix protein 1
- Splicing factor 45
- Probable ATP-dependent RNA helicase DDX5
- Pre-mRNA-processing factor 40 homolog A
Sequence:
MGSDKRVSRTERSGRYGSIIDRDDRDERESRSRRRDSDYKRSSDDRRGDRYDDYRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERESKTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESVQSVDYYCDTIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLSDGNRVSAFSVASTAIAAAQWSSTQSQSGEGGSVDYSYLQPGQDGYAQYAQYSQDYQQFYQQQAGGLESDASSASGTAVTTTSAAVVSQSPQLYNQTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGTKYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSHQQSGLPPAKEGKEKKEKPKSKTAQQIAKDMERWAKSLNKQKENFKNSFQPVNSLREEERRESAAADAGFALFEKKGALAERQQLIPELVRNGDEENPLKRGLVAAYSGDSDNEEELVERLESEEEKLADWKKMACLLCRRQFPNKDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAGTVNYEQPTKDGIDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME
Protein: Zinc finger protein 444 (Endothelial zinc finger protein 2) (EZF-2) (Zinc finger and SCAN domain-containing protein 17) (Q8N0Y2)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
Interaction partners:
- Zinc finger protein 446
- Zinc finger protein 24
- Scavenger receptor class F member 1
- Zinc finger and SCAN domain-containing protein 30
- RNA-binding protein EWS
- SCAN domain-containing protein 3
- Zinc finger protein with KRAB and SCAN domains 3
- SCAN domain-containing protein 1
- Zinc finger protein with KRAB and SCAN domains 4
- Zinc finger and SCAN domain-containing protein 32
Sequence:
MEVAVPVKQEAEGLALDSPWHRFRRFHLGDAPGPREALGLLRALCRDWLRPEVHTKEQMLELLVLEQFLSALPADTQAWVCSRQPQSGEEAVALLEELWGPAASPDGSSATRVPQDVTQGPGATGGKEDSGMIPLAGTAPGAEGPAPGDSQAVRPYKQEPSSPPLAPGLPAFLAAPGTTSCPECGKTSLKPAHLLRHRQSHSGEKPHACPECGKAFRRKEHLRRHRDTHPGSPGSPGPALRPLPAREKPHACCECGKTFYWREHLVRHRKTHSGARPFACWECGKGFGRREHVLRHQRIHGRAAASAQGAVAPGPDGGGPFPPWPLG
Protein: Cyclin D (Q24158)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
QMSSPAIIRDQSSICSSLGDAESDSHPDAQNNAVVCNMKELVYIYASVDSAAKNPEQLEPPPPPPPPPPPPPTATQSIQSYPRYISQEPPTSHCQRLDERLTTTADPPATDNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKDITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGLKWHLRSGHNLHFFLSLMTDLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLPLPKAPAECVEQHQQQHNFGSAAPHRTHTCKMQAQAQAQNEIQDVTF
Protein: Aspartyl-tRNA synthetase 2, mitochondrial (A0A3B3ITK9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIMESQRLELIRLMETQEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLWVVDFPLFLPKEENPRELESAHHPFTAPHPSDIHLLYTEPKKARSQHYDLVLNGNE
Protein: Stress-activated map kinase-interacting protein 1 homolog (Q9NA80)
Organism: Caenorhabditis elegans
Function: May interact with a MAP kinase. May act on Ras-regulated pathways (By similarity).
Interaction partners:
- Target of rapamycin homolog
- RICTOR_N domain-containing protein
- Target of rapamycin complex subunit lst8
- Serine/threonine-protein kinase smg-1
- DAF-15
- ethanolamine kinase
- Serine/threonine-protein kinase sgk-1
- TPR_REGION domain-containing protein
- Transthyretin-like protein 1
- Ribosomal protein S6 kinase beta
Sequence:
MGHVDREDLLNVIRHELRLEDDDGPGLCSRLLLNPDRKCRAGGLPLDFRLKNGDLMDDGDAGFDDIYEIPLYEEPIHTRTLINDSLALRTAEKIKEEGRRDNFYTGPLDELFVKQEVNWPPKTPISTEKSAIERYLEENSANLNNPLGEYSKFAATTTDPSRQIEIIIPMSCDEEIGFKTLKIEVLTTARIREVIGYCLLQYYLTFDSYLPGEVDDYQFYLAEEDGEIEHELPPLDSSKLVGQVGFTCLGLVSRIKKNGNSRQKRAVAVWFVDKDQYVIEVDNMEKPLRWLRDEAFRLREETVKEREPLFQGLLDIKEYYMEAVDNFDVKLDLEASISSARSLEFVMIRKNSSRAGFHPRGGRYGRQMSAMLTLKMPNSPIAAGPMTPLPTVMEESPAVAGTSNGFGFPKAESCGAIASTPGVTWNDDGGQLSSFIVQRIHKFKPKWKANLIFRWTCFEIEKYREDRSAFLPQGYQKHTKVPWEYVGGVRTQLKDAKAGRVDMWQITFFWLPVLSDETVKDVIGDAEWNLNLVAKIYANEEKWRSVTLETFFKQDVDEIFSQTNSILQARDASIYKAFSHSSFGTLSPAASADLALMESAEAIVSPSSDAPSRSSNGKNGGKFRKMSSLMASVMGRRKSDSK
Protein: Tagatose kinase (EC 2.7.1.101) (A9CES5)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Function: Involved in galactitol and D-altritol catabolism. Catalyzes the phosphorylation of D-tagatose to D-tagatose 6-phosphate.
Interaction partners:
- D-tagatose 6-phosphate 4-epimerase
- Galactitol 2-dehydrogenase
Sequence:
MRQASVLAPHTNGPTVTAGEILVEIMATTVGDGFLEPQTLIGPFPSGAPAIFIDQVARCGGTAGIIAAVGDDDFGRLNIERLRRDGVDVSAITTIADRPTGSAFVRYRENGARDFVFNIAHSAASETRMTDEAQALIEKAGHVHIMGSAFAIAGIGAIILEAVKSVKARGGSVSFDPNIRKELAQGDEGRRLIDDLLAVTDLLLPSGEELQAASGLDDEEAAIEKLLAAGIGEIVLKRGANGASHFSRAHGRIDAPGLEVEEIDPTGAGDCFGATYLTCRRLGMRPGKALVYANASGAHNVTKRGPMEGAASLAELDAFMAAQLSEEVL
Protein: Muscle wasted, isoform D (RE27864p) (Q8MS31)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00810}.
Interaction partners:
Sequence:
MFCSNTNSKTAAQPKRSRSDDEAAKLRRANRQEEMLRQMLQPDTTEERNRKDAIFAMNFYEKVEEALLSANRLDDCKKFNSILQNFDPRQEKVSSLYLKVEEILLPTHPELAEVFLNFLLPAEAAEMGKFFEHFMICNATNFINKLNIYFSKQPAQIRKIYACLNELAEMPNVSMKKVENKIMPLLKGNQFLIDWFVQQFPQGKPPKRILSPVETINLHDVQNNTTGEYTETIQEFTDVPTPSKPGCHLKYINGRIFYGAKILLPAKLSFMAASIYNEQSHDVPPVSSDSINCAHGIRAQGEKLLSMASNTDSDDGADRSEEDDASRALIIDTTSDEQNSCSSIEMCDETGLRAHAIRLNPGLYTNSSFNNAATSTPNLGNSHQSHHPHAKKTAINFGEISPRKQSAFNNSGLSPLSAAPNSSPQVDKRKSPTKKIRSPLNQTQSRQRANNQPMVVIHESQPSSSPAIECAKRLRTLIDQESVRDAADTKAGIRIIAQAKQQPPNQCSSEAITKVEVVSLDESAENMPFCTNLKMDTDQSEEELEPLQLSAGNTPQHVITTQFDSDEDCKLDVVATLANCTTTEDRSESAAALPATTSHSESGSSHSAPWTREEDKVILIEMKIGARDREQLIRRMRAKLKNRSIEELRSRHQFLMDFLSKLQGK
Protein: Neuronal acetylcholine receptor subunit beta-3 (P12391)
Organism: Rattus norvegicus (Rat)
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: Synaptic cell membrane {ECO:0000250|UniProtKB:O70174}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O70174}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Neuronal acetylcholine receptor subunit alpha-3
- Acetylcholine receptor subunit alpha
- Acetylcholine receptor subunit epsilon
- Neuronal acetylcholine receptor subunit beta-4
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor subunit beta-2
- Neuronal acetylcholine receptor subunit alpha-9
- Acetylcholine receptor subunit delta
- Acetylcholine receptor subunit beta
- Neuronal acetylcholine receptor subunit alpha-2
Sequence:
MTGFLRVFLVLSATLSGSWVTLTATAGLSSVAEHEDALLRHLFQGYQKWVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEEYGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRREGFYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQRLPRWLCMKDPMDRFSFPDGKESDTAVRGKVSGKRKQTPASDGERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIASVLGSILIFIPALKMWIHRFH
Protein: TFIIH basal transcription factor subunit (Q388I1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- TFIIH basal transcription factor subunit
- TFIIH basal transcription factor subunit
- TFIIH basal transcription factor subunit
- TFIIH basal transcription factor subunit
- Uncharacterized protein
Sequence:
MRAQSDLSPSSVSELRSKLKGVRVEVGSLVSFRDEPAFEMVMRLNKRHNGNLVSAVLSKGNAACGLGGDASGSGEGIGEGRVMADRSRHVEELRMVFIPKAYGAFLEDEMQKWLDPFRGRGEANRTKRKRDEVDDNEVTDIDSDVDTDECDDADSFRSV
Protein: GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Glycosylphosphatidylinositol-anchor biosynthesis protein 10) (P86936)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- GPI mannosyltransferase 1
- GPI ethanolamine phosphate transferase 3
- Dolichol-phosphate mannosyltransferase subunit 1
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Alpha-1,3-mannosyltransferase, putative
Sequence:
MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVFFPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFRMGATLDELLAKRELELAEEMRQSKTKGFSYFREVFVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFTRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIATCYTVPGYSYMHRKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSFNMGDLEESRKASELQSVVMPKSAPHPDAMVMTRAVAKEIEEPFLKRHGYRLYRTFLHSPLTLAPYEDIYIQMWVKVTK
Protein: BTB (POZ) domain containing 10, isoform CRA_a (Epididymis secretory sperm binding protein) (GMRP1) (D3DQW7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAGRPHPYDGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML
Protein: Uncharacterized protein At3g10930 (Q84TK4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein MKS1
- Kinesin-like protein KIN-12F
- Kinesin-like protein KIN-12E
- Ethylene-responsive transcription factor 5
- Kinesin-like protein KIN-14Q
- Kinesin-like protein KIN-14R
Sequence:
MLFRKGVVRGLDPARKLTTSRLSTILSRVFCPNSYFFLFLFFRDSLIFRFQIEIIVNVTCITEIYSRSLGKMRILFGNVSRNDQDLDYHLVSFHQYFFDKR
Protein: Nerve growth factor receptor b (Nerve growth factor recptor) (E2DGP8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
- Neurotrophin-7
- Nerve growth factor
- Neurotrophin-3
- Neurotrophin receptor-associated death domain
- Nerve growth factor receptor a
- Adenosine receptor A2c.
- Fibroblast growth factor
Sequence:
MFTVTVVFLLVGEALSSRDTCPSGAFTTRGECCKQCQPGEGMVKPCGATQTVCEPCLDSETFSENFSHKDKCLPCTQCSELMRMLTPCTDANDALCVCDYGFFLNQLSGRCEACTVCPVGQGVQVPCNFERDTVCEKCEDDTYSDQDTSFDPCLPCTVCDQPEMEVKSCTPVSDAVCQDFDAPNSSPSPSAPPPTPYFTPSPSIHKFSSPGPSVVSYTEKLLPDNPTESVTTTDPGQKRLHGLSDNLIPIYTSILAAVLLGLVAFIIFKRWNSCKQNKQANNRACSANPSQTPSPEGEKLHSDSGISVDSQSLQDGQGPPHTVVKIDGGSALSLPLHTREEVEKLLNRTNEGEESAANEETDWCSLAGLLGYKEEHIANFKQEERPIQALLSHWASQDSANIDTLCTALKKINREDIAQSIIVKPTATSAV
Protein: Gap junction delta-3 protein (Connexin-30.2) (Cx30.2) (Gap junction alpha-11 protein) (Gap junction chi-1 protein) (Q91YD1)
Organism: Mus musculus (Mouse)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}.
Interaction partners:
- Gap junction gamma-1 protein
- Gap junction alpha-1 protein
- Gap junction alpha-5 protein
- Gap junction beta-2 protein
- Gap junction beta-4 protein
- Gap junction alpha-4 protein
- Gap junction alpha-8 protein
- Gap junction alpha-3 protein
Sequence:
MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQLAPPCARGRAEAPCSPCALRARRARRCYLLSVALRLLAELAFLGGQALLYGFRVDPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRAKLLPPPPPSPSLPSQRGDPDPFGPPAYAHRSPAGDSEGEGGSGHSKASLATVRQDLAI
Protein: Uncharacterized protein (Q9HUD6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable transcriptional regulator
- TonB-dependent receptor
- histidine kinase
- Outer membrane assembly lipoprotein YfiO
- Metallo-beta-lactamase domain-containing protein
- Uncharacterized protein
- L,D-TPase catalytic domain-containing protein
- PNPLA domain-containing protein
- Probable outer membrane protein
- Protein TonB
Sequence:
MKPAIKRACLLGTALFSLCASAAQAAGVLVGTWDLRGNGQLAAVYRDGANLQVVEGGSTRNYSFGNVVWSVFGATDTDGQPGAEILVKAGPDLVIVSHASTTQRKYPVGNVSWAIMRATDVDNVAGDEVILSIGNGVRTVFDRTRTQRDATFSYNGTWGLFDVADVDGAPGKELVLNMGNGVKVIDPRTSGAKDFTFSGYHALAQIADLDGQPGAEIIGRTSTGIYVISNASSRKEYSIGASAWALYGGTADTDGKPGNELIVVMQGKVRVIHHASGASSDYRIGDVNYSIDSVADMDGQPGAEILVRDANGKLFVINDRTGKVSS
Protein: Telomere repeat-binding protein 3 (Protein TRF-LIKE 9) (Telomeric DNA-binding protein 2) (AtTBP2) (Q9C7B1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds specifically to the plant telomeric double-stranded DNA sequences. At least 2 repeats of telomeric sequences are required for binding. Induces DNA bending.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
- DExH-box ATP-dependent RNA helicase DExH6
- UV-stimulated scaffold protein A homolog
- Protein FAR1-RELATED SEQUENCE 9
Sequence:
MVFKRKLDCLSVGFDFPNIPRAPRSCRRKVLNKRIDHDDDNTQICAIDLLALAGKILQESESSSASSNAFEEIKQEKVENCKTIKSESSDQGNSVSKPTYDISTEKCVVNSCFSFPDSDGVLERTPMSDYKKIHGLMDVGCENKNVNNGFEQGEATDRVGDGGLVTDTCNLEDATALGLQFPKSVCVGGDLKSPSTLDMTPNGSYARHGNHTNLGRKDDDEKFYSYHKLSNKFKSYRSPTIRRIRKSMSSKYWKQVPKDFGYSRADVGVKTLYRKRKSCYGYNAWQREIIYKRRRSPDRSSVVTSDGGLSSGSVSKLPKKGDTVKLSIKSFRIPELFIEVPETATVGSLKRTVMEAVSVLLSGGIRVGVLMHGKKVRDERKTLSQTGISCDENLDNLGFTLEPSPSKVPLPLCSEDPAVPTDPTSLSERSAASPMLDSGIPHADDVIDSRNIVDSNLELVPYQGDISVDEPSSDSKELVPLPELEVKALAIVPLNQKPKRTELAQRRTRRPFSVTEVEALVQAVEELGTGRWRDVKLRAFEDADHRTYVDLKDKWKTLVHTASISPQQRRGEPVPQELLDRVLRAYGYWSQHQGKHQARGASKDPDMNRGGAFESGVSV
Protein: DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein homolog) (O60870)
Organism: Homo sapiens (Human)
Function: Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo (By similarity). Binds via its C-terminal domain to RNA in vitro.
Subcellular location: Nucleus {ECO:0000269|PubMed:11880372, ECO:0000269|PubMed:12359749, ECO:0000269|PubMed:12754299, ECO:0000269|PubMed:12853634, ECO:0000269|PubMed:15831485}. Cytoplasm {ECO:0000269|PubMed:11880372, ECO:0000269|PubMed:12359749, ECO:0000269|PubMed:12754299, ECO:0000269|PubMed:12853634, ECO:0000269|PubMed:15831485}. Note=During S phase, strongly associated with the nuclear matrix, and to chromosomal DNA in the presence of DNA damage. Also shows cytoplasmic localization in elongated spermatids. {ECO:0000250|UniProtKB:Q8K339, ECO:0000269|PubMed:11880372, ECO:0000269|PubMed:12359749, ECO:0000269|PubMed:12754299, ECO:0000269|PubMed:12853634, ECO:0000269|PubMed:15831485}.
Interaction partners:
- Methyltransferase-like protein 22
- RNA-binding motif protein, X-linked 2
- Splicing factor 3B subunit 3
- Splicing factor 3A subunit 3
- Splicing factor 3B subunit 1
- Splicing factor 3A subunit 2
- BUD13 homolog
- Pre-mRNA-splicing factor 38A
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- Zinc finger matrin-type protein 2
Sequence:
MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQEVPTFTELSRENDEEKVTFNLSKGACSSSGATSSKSSTLGPSALKTIGSSASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVKIITKKLGEKYHKKKAIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEGIQYEDISKLA
Protein: alpha-amylase (EC 3.2.1.1) (Q8MLY6)
Organism: Drosophila kikkawai (Fruit fly)
Interaction partners:
Sequence:
MFLTKSIVCLAILALASAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGFAGVQVSPVNENAVKDSRPWWERYQPISYKLVTRSGNEEQFASMTRRCNAVGVRIYVDVIFNHMAANGGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAISNYNDANQVRNCELVGLRDLNQGNSYVQEKIAEFLNHLIDLGVAGFRVDAAKHMWPADLGVIYGRLKNLNTDHGFSSGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKAFRGKDQLRYLSNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFSDTDQGPPTTDGHNIASPSFNSDNSCSGGWVCEHRWRQIYNMVAFRNAVGSDAIQNWWDNGSNQIAFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGTKNGSSCTGKTVTVGSDGRASIYLGNSEDDGVLAIHVNAKL