wanglab/gogpt-training-data huggingface dataset:
Protein: Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog) (Q9H7L9)
Organism: Homo sapiens (Human)
Function: Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Subcellular location: Nucleus {ECO:0000269|PubMed:21239494}.
Interaction partners:
- Histone deacetylase 2
- Histone deacetylase complex subunit SAP30
- Paired amphipathic helix protein Sin3a
- Histone-binding protein RBBP7
- Histone-binding protein RBBP4
- Paired amphipathic helix protein Sin3b
- Histone deacetylase 1
- Histone deacetylase complex subunit SAP18
- AT-rich interactive domain-containing protein 4B
- Inhibitor of growth protein 1
Sequence:
MSAAGLLAPAPAQAGAPPAPEYYPEEDEELESAEDDERSCRGRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
Protein: Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) (P00959)
Organism: Escherichia coli (strain K12)
Function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Subcellular location: Cytoplasm.
Interaction partners:
- Arginine--tRNA ligase
- Leucine--tRNA ligase
- Glutamine--tRNA ligase
- Proline--tRNA ligase
- Lysine--tRNA ligase
- Lysine--tRNA ligase, heat inducible
- Methionyl-tRNA formyltransferase
- Glutamate--tRNA ligase
- Asparagine--tRNA ligase
- Tyrosine--tRNA ligase
Sequence:
MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMRQVEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
Protein: AT11515p (Q8MZD0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSINKSIRGSRRTRRSLASGGGDLIGPYIYCINFYDNGLSAVRDEFVKRLESGLRRAMFVIDLDKEVAEANYQFQRKSRTKKAGSLDMKSLDPLNIVLQCIQNCVEEFDRITKQIESEANFDLYSYWQRNIPAQLKNLLAPKKKGAPDTKRDLNTARSKTGKTSSDKMRLEKIKCSSVTAKEHHKVGKGAPVSKREYIRDNPTFTKMLILIVGQMDNDFYKLLLAYEQPLRAIINFMPEESAYDILVPRPRREQQLQEALAAIQKDIHSLRKRTPTKPVGIFQQRLPQMSACMAAKFTDDIFDQLSWYMYDVETLREWYRSYYVDPYKETNIKMDPSMSLVEAFHIVESLSIQGHYLKTQMPASRNDNGTVYLYLESLMSTFGNPKELMTETEVLLLANPTPSVQTRVLDKVKVYANSFKSIVKMHKNDRIFVEEANGLLSNLISYMDQSLMRNVYHGCLEYNLLRRYFTSGYINSSLKCQPYNGDVEPIYLPKFAELYLTDDSVMQRIIELVKDYDDFSLEEVQPNVHLYTFRRSLNEVFEQENQTVIPTRLCFRDFTLYEMENFLKDLVTPQRFNEVTESYLSRQTESADNIATQDPFIVRCNEENDSVPIDPKVFVRRKSIKEQLAKKKEKERKEQEESRTASRKVSVAQDGLLSSRTFRQSQARATIASILQAKDSTADSKHAFFVGLGRNHPLLEGYNLDDTRQTIKCKTSKYFFEEGRIVLYEERWNFRQMNKCLALEIGGQEVHFRSADNPLGVTAADSSVRIESKNGISLRVLATQTECAKAVLNFPNGLSTYCHDTHTEHVWQYQENVLDESRRVCTPYGCVISFYQSTDTIVIMRYNGEVYQLFTFTEADNEEEEDLNSEFINACSTQSTYSSYQPIRDSKKKQRSCENSLKKTSTTRSVGGLDSIIRPSMFSVDSKKSQSSKKSIGGKRKSQLLKEQQAAALFESIKFELNYLNFIMALYKLSYRHLKLTTSLGSVVHVQRDGKIWCGKPYRNTEWHDYYANESYSMRDDGVKMVWTLGELRCYHNDGTVITSETAEGWDPGTDVDEIDMEISSSSSHANVEIQPSHIFRKETIFINDPEGLPFKDVSISSSQGVVSQRMSLRSKEISSSSDVMPEEEEGEVDLEKSYITFLPNSYFIAHKVYAGIRFTFSHITNVDLHLDTSIFTCDNLKVRVFRAPLTAGVQYSEPVENPSSAADPDEWTKPEVCPSTKSQRSDRSFEETTSSEEQSAEDMDLDVACVEVECSNLALTLFGDRVIIQTHLRKFGCDENAKCDLQVRDDIELKVNFGESLLTTFRNWVDELTSFINCFCPKRRTLYFLETQNRSCQRKGFELHKSVPPLGKYNLCAGNYFIDVNELTSVNSKMQNRHDWYEQDMQKFPRFQTRKKPVKPDFPMVLNSRIYVEIPAQLANTDRIHQFVSEFDSIKYRKQRYRFNEAIMFHLYPRLQLLVQQEISKRSWKNHHEENRRRMFIEQQRFSLYMAMLKHKVYPSYFQFKDQFNSHVRNIEFFQFMTSKCNEKTHPDDIITDPAEEPSPSIKPKFKKNKCVCPKYLKSLD
Protein: Serpin 4 (Q7K8Y5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- PAPS synthetase, isoform D
Sequence:
MDYRLVPCGCWLLPLLGLALFPFPPVHTADVTMADAAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQKDLPLFWGSVVRLEENTFASSEHDEL
Protein: Co-chaperone protein HscB (Hsc20) (P0A6L9)
Organism: Escherichia coli (strain K12)
Function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
Interaction partners:
- 2Fe-2S ferredoxin
- Chaperone protein HscA
- Iron-sulfur cluster assembly scaffold protein IscU
- Iron-binding protein IscA
- Protein IscX
- HTH-type transcriptional regulator IscR
- Cysteine desulfurase IscS
- Iron-sulfur cluster assembly protein SufA
- Iron-sulfur cluster assembly protein CyaY
- Chaperone protein DnaK
Sequence:
MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
Protein: Uncharacterized protein (Q4GYV1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Trans sialidase, putative
Sequence:
MDSLRSLPAHPPIRSSKEREKGLRRLRVIACGIEIDIPAEGETSVRALMRAVVSLAFPDRRSHGTHCCLFHGDRALPESTRVAELPPNAVLHLHFVADGLGTGITRSEERDAVPYTHTVPGANRGILRHSASPVMLSPLDTIQLQQRGGSYDGPRMPNRISSGPSSTSPMPNPLRRYGQWQQRNIGLTASATMMGSSTDAGTGSRATLPLPMGSYPRLRREYQTTSPARDQLTTDGSRISITVMLLKRNTTEDKDNAKGDDQQATSVTSLECGSGGASSSDGTVAYRRLRVESDYPVGTLREFFGITSDYCIYLGETAIKDDRAPFGSLQGVSTQTFSFRPYPTARAGLSLATTSVNVAHTNAGKAKSKVGEGKDKTTKSVNSNLLSSSSPSGVGKTKSELDETKEKEKEKVEVEVAAEKEKEKETRSETVEYMKLNAVPVTDVNSIGDSDGGGGGGGGVSSEGQQKKHKKCVTAEGPESVGKAGNCECSSNDGNASTVGDPLETTMPFESPSKATRSRLAAEALLSQTHPGPFLGSGDALSKARSLVRAELMGEPPLHEFGSLSFGAGLGRRFGGGRVEAGGVRLALRPHSLAPLETSGDVRGWREEGQTQHHYGTVTITPPTPTERGTVVVPVPPLRPVDVLVDDTNVKGHHTLAPLSGVSHPVSILSSGLMQRHRRNVVGSGPVIVEEKQQNNTVSQQTPPSVDPTKEKN
Protein: CRM-domain containing factor CFM2, chloroplastic (Protein CRM FAMILY MEMBER 2) (AtCFM2) (Q8L7C2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds specific group II introns in chloroplasts and facilitates their splicing. Acts on both subgroup IIA and subgroup IIB introns. The substrates of the subgroup IIB also require the CRM domain proteins CAF1 or CAF2, with a simultaneous binding of CFM2 and CAF1 or CAF2. Can bind to and promote the splicing of the single group I intron in chloroplast tRNA transcript of trnL-UAA gene.
Subcellular location: Plastid, chloroplast stroma {ECO:0000305|PubMed:18065687}.
Interaction partners:
- Protein THYLAKOID ASSEMBLY 8, chloroplastic
- Transcription termination factor MTERF4, chloroplastic
- Ribonuclease III domain-containing protein RNC1, chloroplastic
- Pentatricopeptide repeat-containing protein At3g18110, chloroplastic
- At4g39040
- Pentatricopeptide repeat-containing protein At2g15820, chloroplastic
- Pentatricopeptide repeat-containing protein At5g04810, chloroplastic
- NAD
- Protein WHAT'S THIS FACTOR 1 homolog
- ATP synthase subunit b, chloroplastic
Sequence:
MLLPLFHQQPLILAKTFPDRIFPPFLVPNTLVSRRNVSRANSGIFCSSASGRKTLPQSAIQRIAEKLRSLGFVEEKHDSPTRRITGEESGKNSPGEIFVPLPKQLPIHRVGHTIDTSWSTPSYPVPKPGSGTAISRYHELKRVWKKETEMERKKEEKVPSLAELTLPPAELRRLRTVGIRLTKKLKIGKAGITEGIVNGIHERWRTTEVVKIFCEDISRMNMKRTHDVLETKTGGLVIWRSGSKILLYRGVNYQYPYFVSDRDLAHEAASGASSMDQGVVDSREKQSIAESSAPSITNKMVKPMLTQGVGSPDKVRFQLPGEVQLVEEADRLLEGLGPRFTDWWAYDPLPVDGDLLPAVVPDYRRPFRLLPYGVSPKLTDDEMTTIRRLGRPLPCHFALGRNRNLQGLAVAIVKLWEKCELAKIAVKRGVQNTNSELMAEELKWLTGGTLISRDKDFIVLYRGKDFLPSAVSSAIEERRRQTMIMENSSVHGNKLTENEEEIKPRAVKEDIELEAKDQKDHIQTHQMKSRQRNSPEAILEKTSMKLSMALEKKANAEKVLADLENRESPQLSDIDKEGITNDEKYMLRKIGLKMKPFLLLGRRGVFDGTIENMHLHWKYRELVKIICNEYSIEAAHKVAEILEAESGGILVAVEMVSKGYAIIVYRGKNYERPQCLRPQTLLSKREALKRSVEAQRRKSLKLHVLKLSNNIEELNRQLVEDSATNETWSDGESSNMMVEEETENQHTEPEKAREKIELGYSSDLSVPSSGEENWEDDSEGEVDPLTTSSQEYQEDESESASSQRHEGNSLDSTANLSVFAETGSANASSFHDRSLPHNSFLNANRKLPGSSTGSGSQISALRERKSENDGLVTDLSNRERLILRKQALKMKKRPPFAVGRSNVVTGLARTLKMHFQKNPLAIVNVKGRANGTSVQEVIAKLKEETGALLVSQEPSKVILYRGWGAEEEMKSFYPNNNVKSSINLPSTRSFVDDPPHVSPALIEAIRLECGL
Protein: Glycerol-3-phosphate regulon repressor (Q51391)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Repressor of the glycerol-3-phosphate regulon.
Interaction partners:
- Glycerol kinase 2
- Glycerol-3-phosphate dehydrogenase
- Phosphofructokinase
- protein-N
- Glycerol uptake facilitator protein
Sequence:
MNLPPRQQSIIEEVRERGYLSIEEMAQMFAVTPQTIRRDINQLAEQGLLRRYHGGAAYDSSIENTAYTMRADQMRDEKQRIAEAVASLVPDNASLFINIGTTTEAIARALLNHRNLKIITNNLHVAATLSAKEDFEVLVAGGTVRSDGGIVGQAAVDFIQQFRVDFALVGISGIDEDGSLLDFDYQEVRVSQAIIDNARQVFLAADSSKFGRNAVVRLGPISLVNRVISDSPPPAAIARLMAQHKVHLDLV
Protein: Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase) (P49419)
Organism: Homo sapiens (Human)
Function: Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism.
Subcellular location: [Isoform 2]: Cytoplasm, cytosol {ECO:0000269|PubMed:20207735}. Nucleus {ECO:0000269|PubMed:20207735}.; SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:20207735}.
Interaction partners:
- 3',5'-cyclic-AMP phosphodiesterase 4A
- Choline dehydrogenase, mitochondrial
- Alpha-aminoadipic semialdehyde synthase, mitochondrial
- 4-aminobutyrate aminotransferase, mitochondrial
- High affinity 3',5'-cyclic-AMP phosphodiesterase 7A
- Betaine--homocysteine S-methyltransferase 1
- cGMP-specific 3',5'-cyclic phosphodiesterase
- Rap guanine nucleotide exchange factor 3
- Amine oxidase [flavin-containing] B
- Amine oxidase [flavin-containing] A
Sequence:
MWRLPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
Protein: Mevalonate kinase (MK) (EC 2.7.1.36) (Q57Y11)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU363087}.
Interaction partners:
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
- phosphomevalonate kinase
- Diphosphomevalonate decarboxylase
- Diphosphomevalonate decarboxylase
- Hydroxymethylglutaryl-CoA synthase
- Farnesyl pyrophosphate synthase
- Isopentenyl-diphosphate delta-isomerase, putative
Sequence:
MHVAVKDKTTRHHIGYGKVILFGEHFVVYGAESIVAGINEYTTCEISRLKHKPNVVEVIDERPAVPGYIKEKREEQRVAHGLVLRHLNIDTSKDGLLVKLGGPLVPSSGIGASASDVVSLSRALNELYSLNLSEEAVNRSAYAGECGYHGTPSGVDNTAATYGGIILFRRALKKSVFSRLALGKTLSIIVCSTGITASTTKVVADVARLKAAQPSWFDDLFEQYNACVREAKKALQSGNLRRVGELMNINHTLCQKLTVSCPELDAIATCCRTFGALGAKMSGTGRGGLVVALAANTQERDRIAKAVREQCKEAKFVWRYSVQPGGSKL
Protein: Syntaxin-10 (Syn10) (O60499)
Organism: Homo sapiens (Human)
Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Interaction partners:
- Syntaxin-16
- Vesicle transport through interaction with t-SNAREs homolog 1A
- Vesicle-associated membrane protein 3
- Vesicle-associated membrane protein 4
- Alpha-soluble NSF attachment protein
- Vesicle transport through interaction with t-SNAREs homolog 1B
- Syntaxin-5
- Syntaxin-7
- Syntaxin-12
- GRIP and coiled-coil domain-containing protein 2
Sequence:
MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLLLVLILLFSL
Protein: MFS domain-containing protein (Q17675)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MINSMLNEDYRVYPKRWIYLLAVSMINFSNGNTWITYAAITFYTNNYYSNSNAALFFNVIFMVLSIPVGFLACWWIDKFGLRSAYHIGTWANFIGNIIRLVASGTFIDPSLRFPIAITGQAVAAFAQPFVMFLPTKLAAYWFADNERAIANTLSSMSNPIGIAVMYSLAPVFVNKTTPDNFFNMNIAVTAVAVIPVILSLFINKSKPPTPATPSRDTDVDAPPFLEGVKICFKSKTFIVLSICLGGGVGLFNALYNNLQPALCVKGYNPTFNGGMGTLLIMSGLVGAAISGIIVDKWGEFEKVMKVSFCIAGVAAASLSICINYEGVQWWVILSIFIFGAAGFSIYPIGLEMGVEATFPVAEATSTGLIIMIGQVQGVFYVIMTNLAVGKPDPHDMAIQTCVDTNSQNHTVLTWKWPFLIWLICISVLITSFVAFFWPKYKRRNYEQGKKWNELDL
Protein: SAM-dependent MTase RsmB/NOP-type domain-containing protein (Q57V63)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nucleolar complex protein 2
- 60S ribosome subunit biogenesis protein NIP7 homolog
- RNA-binding protein, putative
- Nucleolar GTP-binding protein 1
- Methionyl-trna formyltransferase
Sequence:
MSRNHNRRGGIKRSRSNSEWATDKRDVTTLSNAAFEAYYKDNVIPAEEWESFMEALRRALPTAIRVHPSVPCATAVSEYVRSRLLHAALPVQPIPFIPDNMAFQSSISRGDLKRTTELKEVKRLISALNEGGFLTRQETVSMIPVVLLQVAPGNRVLDMCAAPGSKTSQILEAVISSNQDGVVVANDLNVARLDVLLHQTARSPGAHPHLIVTNYDGTQFPLLPKEDKFDRVLCDVMCSGDGTLRKSMDMWPRWNTVHGADLHVTQVRVLTRGMMLCKKGGIVVYSTCSLNPVEDEAVVSECLSQAKGTFRLIDPAPFLKDFVTVPGQTDWFLLTKDLTQKLRTFEDAEAYNQSKQAHGFRYRKSMFSNAQVLREQNIHFARRVVPHQQDTGGFFFAAMECVEDYPLEDADVCTAATKQPFSLCSPALQEQVRGSLGLPGSFPACQLYVRNEVAREQKFYFASKATCKFFPKLGARIVHVGCKMFESYAKYSNDKLRFSTEGAASLVPLLPSEFIIEADAAFVLRLGANGTVPASELPSPPPPYSNFLLSCKTSLVETIYVAMERKVSGQFGAKVAEWQLSILKLTLGLPFVECTADGTAADECCAEES
Protein: MICOS complex subunit MIC60 (Mitofilin) (C9J406)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU363000}; Single-pass membrane protein {ECO:0000256|RuleBase:RU363000}.
Interaction partners:
Sequence:
MVLGPAAYNVPLPKKSIQSGPLKISSVSEVMKESKQPASQLQKQKGDTPASATAGDTLSVPAPAVQPEESLKTDHPEIGEGKPTPALSEASSSSIRERPPEEVAARLAQQEKQEQVKIESLAKSLEDALRQTASVTLQAIAAQNAAVQAVNAHSNILKAAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKSVIENAKKKEVAGAKPHITAAEGKLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIKANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQLKPPPELCPEDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGTTQVQPE
Protein: Large ribosomal subunit protein bL9 (50S ribosomal protein L9) (P0A7R1)
Organism: Escherichia coli (strain K12)
Function: One of the primary rRNA binding proteins, it binds very close to the 3' end of the 23S rRNA.
Interaction partners:
- Large ribosomal subunit protein uL6
- Elongation factor Tu 1
- Large ribosomal subunit protein uL4
- Alternative ribosome-rescue factor A
- Large ribosomal subunit protein uL15
- Small ribosomal subunit protein bS6
- GTP pyrophosphokinase
- Elongation factor G
- Small ribosomal subunit protein bS18
- Large ribosomal subunit protein uL13
Sequence:
MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
Protein: Transmembrane protein 25 (Q9DCF1)
Organism: Mus musculus (Mouse)
Function: In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.
Subcellular location: Late endosome {ECO:0000269|PubMed:31424425}. Lysosome {ECO:0000269|PubMed:31424425}.; SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MELPLSQATLRHTLLLLPALLSSGQGELAPQIDGQTWAERALRENEHHAFTCRVAGGSATPRLAWYLDGQLQEATTSRLLSVGGDAFSGGTSTFTVTAQRSQHELNCSLQDPGSGRPANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPPANVTWIDQDGPVTVNASDFLVLDAQNYPWLTNHTVQLQLRSLAHNLSVVATNDVGVTSASLPAPGLLATRIEVPLLGIVVAGGLALGTLVGFSTLVACLVCRKEKKTKGPSRRPSLISSDSNNLKLNNVRLPRENMSLPSNLQLNDLTPDLRGKATERPMAQHSSRPELLEAEPGGLLTSRGFIRLPMLGYIYRVSSVSSDEIWL
Protein: Probable 2-oxoadipate dehydrogenase complex component E1 homolog (EC 1.2.4.-) (Oxoglutarate dehydrogenase A) (Q54VG0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q96HY7}.
Interaction partners:
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- Dihydrolipoyl dehydrogenase, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Aromatic amino acid aminotransferase DDB_G0287711
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Pyruvate dehydrogenase complex subunit homolog DDB_G0271564
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Glutaryl-CoA dehydrogenase, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
Sequence:
MIGLRSISKNKQTINSISKSFYCTSSPSSSSVKLSVTRLIDGYRAHGHLAANIDPLARMERIRSQLLDLDRYNLVKGQSIPSTIDLINQDLTNLDQVVSFLENAYCNDVTAQFDHIESIEEKAWLYEKFEQLQHQNPSKSEKINILKNLIKSEIFDQFMQKKFPTFKRYGLEGNESMMVSCDSIFRESAKNQLKNVVIGMPHRGRLNLLVQMCNYPAKDFFWKVKGNSEFSEGILGVGDVTSHIAVSTDLQFNNNKESVHVSLIHNPSHLEAVDPVAAGKTRAKQFYEKNEGGSESLCLMLHGDAAVAGQGVVTETLQLSQLSGFNIGGCVHVIVNNQIGFTTVPTNGRSNRYSSDIGKFIGAPIIVVNSQSPEQVEKVSRLAVEYRQKFKKDIIIDLIGWRKFGHNEVDEPSFTQPTMYQNIRKRQSIPQKYATQIISQGIFSEQELLEFTQKEQAILEEQFQLSTPENFKYSPMDHLQGKWSGLIQSKHIADDSKLDTGYSVEELSEIANDSVKVPSDFQVHQRLLRSFSNARLEKLKQNQADWATAESMAVGSLMKQGYNVRISGQDVGRGTFSQRHFNLTEQNSDRIYQPLNNMGAKGELDVVNSNLSEFAVLCYEYGYSLESPDTLPIWEAQFGDFINGAQIAIDQFVTSGESKWLRQSGIVILLPHGFDGAGPEHSSCRIERFLQLSDTEAVNVKDDTLINQETNFYFINPSTPANYFHALRRQMIRNYRKPLIVAGPKVLLRHPNCFSTLNEMAPGTHFQTVLSDPDTINNASTIKRVIFCSGKVFYDLQEERKAKNFNDVAIIRLEQIAPFPYQRIQEEINRYSNATKFAWVQEEQQNGGCWSFVEPRFKQRYPQTSQIKYIGRPPLAASAIGISSIHKKEVSQLLIDAFNF
Protein: Probable lysophospholipase BODYGUARD 4 (AtBDG4) (EC 3.1.1.-) (Q700D5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in cuticle development and morphogenesis.
Subcellular location: Cell membrane {ECO:0000255}; Lipid-anchor {ECO:0000255}. Secreted, cell wall {ECO:0000250|UniProtKB:Q8LFX7}.
Interaction partners:
- Alpha/beta-Hydrolases superfamily protein
- Alpha/beta-Hydrolases superfamily protein
- Phospholipase A2-alpha
- Patatin
- Triacylglycerol lipase SDP1
- Phospholipase A I
Sequence:
MSFPRKFGTAIHAALSFIVFFFLDLLDAILCVVYEFVDEILEENSTGCYCTAAAPQSQTTDENELSSETLFGRRNIFRGMWFLGFAREFKSKLSRKLRKSKIHQESVNRWSDCGCKSCKSWTKNEDGNLHVVVKDSTSREYSVQEPSENVIFIHGFMGSSHFWTETVFEHIQKDDYRLLAIDLLGFGESPKPRDSLYTLKDHVDTIERSVIKPYQLDSFHVVAHSMGCLIALALAAKHSNIVKSVTLVAPPYFPSSVEGSVLNRIARKRLWPPLAFGTAVMSWYEHIGRCVCFIICKHHKIWEWLIKLCIGKREIHWKIKDITRHTHHSAWHSMHNVICGGSKVADEHLETLIKSGVKIHLMQGDCDQIVPSHCSGNMKRTFPAVEVDIITGADHDSMISGRGEEFAEKLESIWCSC
Protein: Large ribosomal subunit protein mL66 (28S ribosomal protein S18-3, mitochondrial) (MRP-S18-3) (28S ribosomal protein S18a, mitochondrial) (MRP-S18-a) (Mrps18a) (S18mt-a) (Q99N85)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:P82919}.
Interaction partners:
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein mS40
- Large ribosomal subunit protein mL42
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein mS33
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein bS1m
- Small ribosomal subunit protein uS11m
Sequence:
MAALRRLVSGCGRQLQAFLAGPAATGWLWLPARGLREVVKIQEGKTTVIEGRITETPKATPDPPNPSGQCPICRWNLKHKYTYEDVLLLSQFIRPYGGMLPRRVTGLCREEHRKIEECVKMAHRAGLLPNHRPQLPEGCLPKDKPKLNRYLTRWAPKSVKPIYKKGHRWNKVGMAVGSPLLKDNVCYSRRPLKMMH
Protein: Rhamnogalacturonate lyase A (EC 4.2.2.23) (Q5AX45)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin. Active against linseed rhamnogalacturonan.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Alpha-L-arabinofuranosidase B
- Dolichol phosphate-mannose biosynthesis regulatory protein
Sequence:
MLSKTFLLSSAVLWARVANAAFGITDNGSSYTIDANSPNPLKFTVNKSSCDITSIVYYGSEFQYSGKGSHIGSGLGSATVSATQSGDYIKVTCDTSSLTHYFVVHNGDPIIHMATYITAEPDIGELRFIARLNSNLLPNEEPFGDVSTTSGGSAIEGSDVFLVNGETRSKFYSSERFIDDHRHCISGSAHRVCMILNQYESSSGGPFFRDINSNNGGDYNALYWYMNSGHVQTESFRTGLHGPYSMYFSRSGTPSTNIDTSFFASLGIKGYVAANGRGTVTGKASGADSSMDWVVHWYNNDAQYWTYTASDGSFTSPAMKPGTYTMKYYQGEFPVAETTVTVSAGSSTTKNISGSVKTGTTIFKIGEWDGQPTGFRNADKQLRMHPSDSRMDSWSSTYTVGSSSLSDFPMAVFKSVNNPVTIKFTATSAQTGAATLRIGTTLSFAGGRPQATINSYTGPAPSAPTNLNSRGVTRGAYRGLGEVYDVSVPAGTIVTGENTITISVISGSSGDAFLSPNVVFDCIELFQ
Protein: ABC-type glutathione-S-conjugate transporter (EC 7.6.2.3) (Q9I7N0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Vacuole membrane {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004128}.
Interaction partners:
Sequence:
MADDTSSPMDRFCGSTFWNATETWYTNDPDFTPCFEQTALVWTPCAFYWAFVIFDFYYLKASLDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELPLYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFADGMPRQTKYQRGENEIPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWNQNVRKNYKNKARVEPKAQFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWGDEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFIIQHLQEGNEEEEELNQIKRQISSTADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGGSLRRRTKRQDSHDSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWANDQNVANDTGLRDMYLGVYGAFGFGQVLSKYLSGLALAIGGLHCSMNVFNKLLNTGLKWPMELFDTTPLGRILSRYSKDVDTVDSVLPAITVQLLNTCFGVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQTNPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANLV