wanglab/gogpt-training-data huggingface dataset:
Protein: Dynamin-like GTPase (A0A1D8PN45)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Sla2p
- Regulator of cytoskeleton and endocytosis RVS167
- Fgr32p
- Clathrin heavy chain
- SNAP receptor
- Clathrin light chain
Sequence:
MDETLIATINKLQDALAPLGGGSSSPVDLPQITVVGSQSSGKSSVLENVVGRDFLPRGTGIVTRRPLVLQLINRRPSKDLKKANDLVDVNASESTGGQSENNADEWGEFLHLPGKKFFNFEDIRNEIVRETDAKTGKNLGISPVPINLRIYSPHVLTLTLVDLPGLTKVPVGDQPKDIERQIKDMIMKFISKPNAIILSVNAANTDLANSDGLKLAREVDPEGARTIGVLTKVDLMDQGTDVIDILAGRVIPLRFGYVPVINRGQKDIEAKKTIRDALKDERNFFENHPSYRAKAQFCGTPYLAKKLNGILLHHIKSTLPDIKMRIEHSLKKYQQELSMLGPEMAESPASIALSMITNFSKDYTGILDGESKELSSQELSGGARISFVFHEIFKNGVNAIDPFDQIKDADIRTIMHNTSGSAPSLFVGTQAFEVLVRQQIKRLEEPSIRCINLIFDELVRILSQIISQPQYSRYPGLKEQLSQNFILYLRDLLIPTTEFVNDIIQAEETYVNTAHPDLLKGTQAMSIVEEKFHPKPQVAVDPKTGKPLPPSQQPAQATSPKPEDGSSNGFFGGFFSSKNKKRLQQMEAPPPVLRATGTMSERETMETEVIKLLISSYYNIVKRTVGDVVPKAIMLKLINKSKDEIQKTLLEKLYSSPDLDDLVKENELTVQKRKECVRMVEVLRNASEIVSSV
Protein: Large ribosomal subunit protein bL20m (39S ribosomal protein L20, mitochondrial) (L20mt) (MRP-L20) (Q2TBR2)
Organism: Bos taurus (Bovine)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11279069, ECO:0000269|PubMed:16510155}.
Interaction partners:
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL32m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein uL13m
- Ribosomal protein
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL9m
Sequence:
MVFLSAPLWLRNRITDRYWRVQEVLKHARHFRGRKNRCYRLAVRAVTRAFVRCTRARSLKKRHLRTLWINRITAASQEHGLKYPAFILNLIKCQVELNRKVLADLAIYEPKTFKSLAALSKRRREEGFVAALGDGKEPEGIFSRVAQHH
Protein: 11-beta-hydroxysteroid dehydrogenase type 2 (11-DH2) (11-beta-HSD2) (11-beta-hydroxysteroid dehydrogenase type II) (11-HSD type II) (11-beta-HSD type II) (Corticosteroid 11-beta-dehydrogenase isozyme 2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) (F1QLP1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as cortisol, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as cortisone, in the presence of NAD(+). Cortisol is the primary glucocorticoid in teleosts and is released to increase glucose bioavailability in order to meet the increased energy demands in response to stress. Functions as a dehydrogenase (oxidase), thereby decreasing the concentration of active glucocorticoids, regulating the hypothalamus-pituitary-interrenal (HPI) axis function in adult fish. Decreasing the excess glucocorticoids may be of relevance to brain function and neural proliferation. Plays a key role by catalyzing the oxidation of 11beta-hydroxytestosterone (11beta,17beta-dihydroxyandrost-4-ene-3-one) to 11-ketotestosterone (17beta-hydroxyandrost-4-ene-3,11-dione), the major fish androgen, that activates androgen receptor transcriptional activity. Catalyzes the conversion of 11beta-hydroxyandrostenedione (11beta-hydroxyandrost-4-ene-3,17-dione) to 11-ketoandrostenedione (androst-4-ene-3,11,17-trione), which can be further metabolized to 11-ketotestosterone. Exerts a dual role in fish by inactivating glucocorticoids and activating androgens.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cytochrome P450, family 11, subfamily C, polypeptide 1
- Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
- Hydroxysteroid 11-beta-dehydrogenase 1-like protein
- Hydroxysteroid
- 17-beta-hydroxysteroid dehydrogenase type 3
- Mineralocorticoid receptor
- Aromatase
- Cytochrome P450, family 17, subfamily A, polypeptide 1
- Solute carrier family 3 member 2b
Sequence:
MEDFAVSFWIYIGVMSIFVGGAVKKFLAFNIGAMPSVVVWLGATLLVERLCALCMPAVLARLVLCVCCWLYFTWATPKPSLPVEDKAVFITGCDSGFGNATAKKLDAMGFEVFATVLNLEGEGAKHLRKVCSSRLTLLQVDITQPQQVQQALLDTKAKLGIRDLWGLVNNAGWCVNIGDAELSLMSNYRGCMEVNFFGTVTVTRTFLPLLRQSKGRIVTISSPSGEHPFPCLASYGASKAALNLFINTLRHELDPWGVKVSTILPSAYKTGQSSNAEYWEKQYKSLLQGLSPNLLEEYGEEYLLETKELFQNYAKTANEDLSPVIDTIVEALLSPQPQVRYYAGPGLILMYFICSYLPLSISDRFLQKLFVQKKVMPRALIKQQGLSPNDNNNSIKENMNDSSSNNSNFTKCID
Protein: Protein CREG2 (Cellular repressor of E1A-stimulated genes 2) (Q8BGC9)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000269|PubMed:12408961}.
Interaction partners:
Sequence:
MSLSGRERPAWPGSRLSWLLCCSALLSPAAGYVIVSSVSWAVTNEVDEELDSASTEEALPALLEDSSSIWQQSFPASAHKEDTHLRPRGSARARPAPAARGMFSYRRESGSSEASPGPRVHAGTARSLAHASSWGCLATVSTHEKIQGLPFGSCLAISDGPVHNSTGIPFFYMTAKDPAVADLVKNPTASLVLPESEGEFCRKNIVDPEDPRCARLTLTGRMVTVPPGEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMWVEHIWLQKWYGGVSDIPREEYFKAAPRKA
Protein: Pseudouridine synthase family protein (Q5XVC2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Short integuments 2, mitochondrial
- At4g38020 family protein)
- Large ribosomal subunit protein mL43
- Protein Iojap-related
- Large ribosomal subunit protein uL24c
- Large ribosomal subunit protein uL29m
- Nucleolar complex-associated protein 3
- Large ribosomal subunit protein bL21m
- At1g01640
- Large ribosomal subunit protein uL13c
Sequence:
MKLSRTVLSCLPSLLKPYSSLSWTTKIATIATNFEGMKTVDEADVGISCFISQLPGFRGILKQRYADFIVNEVDMDGNVVHLTSLDLPPEMAVKEEDKAKSCDNVPQNYTSAVESFKSISSVTDAERLEILINQVTSGTDGEVLPVVLDPSSDKSKRTAIHNFVKENFKFLVTDTVDGPDSTSKCIRVRVNSGANNNRGNRSKKRKERGDKPFDSRGSEHWPEHVGKFLRFHLYKENKDTQEALGLIGKMLGVQPKSFGFSGTKDKRSVSTQRVTVFKQQASKLAALNKRLFGIKVGDFCNVKEGLLLGQLMGNRFTITLRGVVADSEETIKQSAESLGKDGFINYFGLQRFGSGSVPTHHVGAALLKGEWKDAVDMILDPRETERHVVNDAREYYKETGDIDGTLRQLPRYLVAERAILQCLKKCPGNYLQALKGIPRTLRMMYVHSYQSYLWNNAASLRVKNYGTSQVVLGDLVSTKVDAAKRMVDSLTSEHNESSEEALDCDQVDDTAVVDLPAERSDLVKVVSIEDLEAGTYSTSDIVLPLPGSRVIYPSNDIAEIYHDLAKKDGISLTESIHGVKEFSITSMTGGYRRVFQKPIDFEWELLTYTDSNKPLAETDLDRIPMNKPVEKVGSTEEIEDESMKSDTNPHDSGETNLKDQTDSNEAEKDTGNPDSEQTQMALKMALTLPSSCYATMAIRELLKTSTSVAYHKTLN
Protein: Protein NRT1/ PTR FAMILY 8.4 (AtNPF8.4) (Peptide transporter PTR4) (Q84WG0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MASIDEERSLLEVEESLIQEEVKLYAEDGSIDIHGNPPLKQTTGNWKACPFIFANECCERLAYYGIAKNLITYFTNELHETNVSAARHVMTWQGTCYITPLIGALIADAYWGRYWTIACFSAIYFTGMVALTLSASVPGLKPAECIGSLCPPATMVQSTVLFSGLYLIALGTGGIKPCVSSFGADQFDKTDPSERVRKASFFNWFYFTINIGAFVSSTVLVWIQENYGWELGFLIPTVFMGLATMSFFFGTPLYRFQKPRGSPITSVCQVLVAAYRKSNLKVPEDSTDEGDANTNPWKLCTVTQVEEVKILLRLVPIWASGIIFSVLHSQIYTLFVQQGRCMKRTIGLFEIPPATLGMFDTASVLISVPIYDRVIVPLVRRFTGLAKGFTELQRMGIGLFVSVLSLTFAAIVETVRLQLARDLDLVESGDIVPLNIFWQIPQYFLMGTAGVFFFVGRIEFFYEQSPDSMRSLCSAWALLTTTLGNYLSSLIITLVAYLSGKDCWIPSDNINNGHLDYFFWLLVSLGSVNIPVFVFFSVKYTHMKV
Protein: Polygalacturonase (EC 3.2.1.82) (E0SKR3)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Interaction partners:
- Pectinesterase A
- Pectin acetylesterase
- Xylosidase/arabinosidase
- 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
Sequence:
MKAMRFSQHHALVLITSVYLFSNQVQAIPTSEPTSPALQAVAPSLDDHSVVLAWHAPEDTSAIADYQIYQNGQPIGLASQNNDKNSPAKPYISAFYKNDASNFHHKVVMQNAKIDGLKANTDYQFTVQTVYADGTTSADSNEVTVTTTTTPQVINITEYGAKGDGTTLNTTAIQKAIDACPTGCRVDIPAGVFKTGALWLKSDMTLNLLQGATLLGSDTAADYPDAYKLYSYSSQVRPASLINAIDKTSSAAGTFKNIRIIGKGAIDGNGWKRSADGKDELGNSLPQYVKSDSSKVSNDGILAKNQVAAAVAKGIDIKLAYSQLRSSLVTLRGVKNAYIADVTIRNPANHGIIFLESRNVVENSVIHQTFDANNGDGVEFINSQNIMVFNSVFDTGDDSINFGAGLGQDAQKQEPSQNAQLFNNYFRHGHGAVVMGSNTGAGIVNVLAENNVISQSDVGLRAKSAPAIGGGAHGIVFRNSAMKNLAKQAVIVTLSYSDNNGTIDYTPAKVPARFYGFTVKNVTVQDSTGSSPSIEITGDSSKDIWHSQFLFSNMKLSGVMPASISDLSNSQFNNIAFSDLRGGTSPWKFGAVKNVTVDGKVVSPSP
Protein: Recombination activating protein 2-like (Q45ZT5)
Organism: Strongylocentrotus purpuratus (Purple sea urchin)
Interaction partners:
Sequence:
MESLDDFGMILLQQASKEGKRKISRKKPQSDLKLNEYYLAEGHFAVMCPVLGAEEPEKKKRIFSSGGARRGGDNSWGDAGRIIEYVVEMDKNDDVTLASVVSCKTTGGRMPALQSAAAIESDSRFYVWGGFDLMEYRCKDDLIILEEGRRRGATGAPVFDIKYVPTTANMVASRRGNTVPVQKGTVPHARTGHTLTRLGETKEALLFGGVMEQEERKSFSVEWELACRDGTFYILDLDTFIWRRVPVPSATLARTYHTAECLETVRSFVIAFVGGVMHDKNTTTRIPINEVLLLTMNSQDTDTAVLSTVTLASDGPSTPVPYISYHATAQVNYNILVSGGFQLQHSSDIPKTSRHASSRVFILDIVGKKYKLLPKTQNNNQFGTAGHVLLTLAPDCIISVGGTSKQISMLSDRKYKPEKCDLLPSCTIAEAEGTVEIQWVQCETPRCGKWVHVYCLKLNSIPEIYFCPHCKNKNDISVCVCSIHLKTCRIHLKKCTIPN
Protein: Berberine bridge enzyme-like C-1 (NtBBLc) (EC 1.1.1.-) (F1T161)
Organism: Nicotiana tabacum (Common tobacco)
Function: Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN). Catalyzes a late oxidation step subsequent to the pyridine ring condensation reaction in the biosynthesis of alkaloids.
Subcellular location: Vacuole {ECO:0000269|PubMed:21343426}.
Interaction partners:
Sequence:
MFPLIILISFSFTFLSASATSGAGEGVANLSTCLINHNVHNFSMYPTSRNYFNLLDFSLQNLRFAASNMPKPTVIILPNSKEELVSTILCCRQTSYEIRVRCGGHSYEGTSSVSFDGSPFVIIDLMKLDDVSVDLDSETAWAQGGATIGQIYYAIAKASDVHAFSAGSGPTVGSGGHISGGGFGLLSRKFGVAADSVVDALLIDADGRLLDRKAMGEDVFWAIRGGGGGNWGIIYAWKIRLVKVPKIVTTFKISKPGSKQYVAPLLYKWQIVAPNLADDFTLGVQMIPIDLPADMKYGNPTPIEICPQFNGLYLGPKTEAVSILNEAFPELNVKNDDAKEMTWIESALFFSDLDNIFGNSSDDISHLKERYLGVKICFKGKSDYVKTPFSMDGIMTALVEHEKNPNAFLVFDPYGGAMDKISAQAIAFPHRKGNLFAIQYYAQWNEEDDAKSNEHIEWIRGFYNKMAPFVSSSPRGAYVNYLDMDLGMNMDDDYLLRNASSRYSSSVDAVERARAWGEKYFLNNYDRLVKAKTKIDPLNVFRHEQSIPPTLGSTQEHNYSSE
Protein: V-type proton ATPase subunit E3 (V-ATPase subunit E3) (Vacuolar H(+)-ATPase subunit E isoform 3) (Vacuolar proton pump subunit E3) (P0CAN7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).
Subcellular location: Vacuole membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- V-type proton ATPase subunit D
- V-type proton ATPase subunit F
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase subunit B2
- V-type proton ATPase subunit H
- V-type proton ATPase subunit B1
- V-type proton ATPase subunit d2
- V-type proton ATPase subunit C
- Vacuolar ATP synthase catalytic subunit-related / V-ATPase-related / vacuolar proton pump-like protein
- V-type proton ATPase subunit a3
Sequence:
MNDADASIQIQQMVRFIRQEAEEKANEISISSEEEFNIEKLQLVEAEKKKIRQEYEKKEKQVDVRKKIDYSMQLNASRIKVLQAQDDIVNAMKEEAAKQLLKVSQHGFFNHHHHQYKHLLKDLIVQCLLRLKEPAVLLRCREEDLDIVESMLDDASEEYCKKAKVHAPEIIVDKDIFLPPAPSDDDPHALSCAGGVVLASRDGKIVCENTLDARLEVAFRNKLPEIRKSLFGKVGAA
Protein: Sodium channel protein (Q20JQ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU361132}.
Interaction partners:
Sequence:
MATMLLPAGPDGLRPFTRESLAAIEQRISEERARNTKDYKADPGDVEEPKPRADLEVGKVLPRIFGEIPAGLVGVPLEDIDPFYFRNQKTFIVLNKGKAIFRFSATSALYIFSPFHCIRRISIRILVHSLFSLFIMCTILTNCCFMAMSDPPLWTKYLEYTFTGIYTFESLIKILARGFCTECFTFLRDPWNWLDFSVIVMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLADVMILTVFCLSVFALIGLQLFMGILRQKCVRSIGHCVNSTYPGNGSFVCNNKTWLSVKDFLTNEDNFYKIEGSKDALICGYSSDAGKCPDGFDCLKTSRNPNYGYTSFDTFGWAFLGLFRLMTQDYWESLYHQTLRSAGKTYMIFFVLVIFLGSFYLVNLILAVVAMAYEEQNQATIAEAWAKEREFQLAMEHLRKEQRALAKQRRKEAEMALAADFCPSPFSRKDSIKCRTRTRSHRTLSEEIEDSFLPKFEPLDEKPAHPLLATLSSHPLSTRRGSQMSIFTFRPRNSSEADFADDEHSVADYGRSRAGSMATPWHKHRTGSIRSHSSQVFTPTLANGRLNISLEQNGITGIGLHTPTTGPKFSMEKVKEGTEPECQNEQVKLTVDVQEEVLPPRRKRGLSSVSFFSDAMDELEEARQKCPPCWYEFAQKYLIWTCSPAWLRVKEGLKVMVMDPFLDLAITICIVLNTLFMALEHYPMTDEFNSMLSIGNLVFTGIFTAEMVLKIFALDPYYYFQQGWNIFDGIIVCLSLMELGLSNVEGLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYQDCVCKISYDCTLPRWHMKDFFHSFLIVFRVLCGEWIETMWDCMEVAGQPLCILVFMLVMVIGNLVVLNLFLALLLSSFSSDNLSAPDEDGEMNNLQIAIARIHCGFSWLLNGIKDLFSGNLTRHRRKSKEAQVTLNHTECNGGLGSLEKYVFPETEDSYMTNPNLTICVPIAPGESDVEFLEEEEEEEDTESSEDEEEKQEVISLSEGSTVDLRKPGEDEEEYSEMADDGMDPEECFPEFCMQRCKCCNINTTQGLGQMWWRLRKTCYQIVEHSWFETFIILMILLSSGALAFEDIYIEQRKVVKVVLEYADKVFSYIFVLEMFLKWIAYGFKKYFTNYWCWLDFLIVDVSLISLVANSLGYSDFGAIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGKCVNRTGFIHNASIVNNKTECLSMNDTQFYWTKVKVNFDNVGLGYLSLLQVATFKGWMEIMYAAVDSRGVEDQPIKEINLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKRMIGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPMNILQGFFFDLVSKQAFDITIMMLIILNMITMMVETDEQSARMETILNNINLAFIVIFTTECLIKIFALRCYFFTISWNIFDFVVVILSIVGIVLADIIEKYFVSPTLFRVIRLARIGRVLRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMANFAYVKKQGGIDDMFNFETFGNSMICLFQITTSAGWNNLLDPILNNSPEECSSSFANTGTNTKGNCGHPSVGITFFVSYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFEMFYEVWEKFDVEATHFIEYAKLSNFADSLSEPLRIAKPNKIKLIHMDLPMVNGDRIHCLDILFAFTKRVLGETGEMDALKQQMEEKFMVTNPSKISHEPITTTLRRKQEEISATLIQRAYRAHLIRRQMKQASYLYRHINQETPWSEEDSAPEQEGLIASMIKENYGPEKMVGTLCYASSPPSYEAVTRSPRDHFKLLISDSRSNEPHKSEETYEETFL
Protein: Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (mACDP1) (Cyclin-M1) (Cyclin-like protein 1) (CLP-1) (Q0GA42)
Organism: Mus musculus (Mouse)
Function: Probable metal transporter.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14723793}; Multi-pass membrane protein {ECO:0000269|PubMed:14723793}.
Interaction partners:
- Transient receptor potential cation channel subfamily M member 6
Sequence:
MAAAAAAAAALGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPVPAAPVPAPSLAPGENGTGDWAPRLVFIEEPPGAGGAAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYASLPPGVGDPGEDSGEAGVHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTSACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYTPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPVLTLLSNRTSLPCSRSDGLRSPGEVVYLRMEEMAFPQEEMPNFEEHRSQQVSLSPVAVPTTAASDPECCNIHLDPEASPCSSDSEENMGKKLLRTLSGRKRKKSADGERASEENSNLTPLIT
Protein: B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein) (O08664)
Organism: Mus musculus (Mouse)
Function: May play an anti-apoptotic role.
Interaction partners:
- Protein SSXT
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
- SWI/SNF complex subunit SMARCC1
- AT-rich interactive domain-containing protein 1A
- Bromodomain-containing protein 9
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- B-cell CLL/lymphoma 7 protein family member A
- BRD4-interacting chromatin-remodeling complex-associated protein-like
Sequence:
MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGTSPRGGGPLILLDLNDENSNQSFHSEGSLQKGAEPSPGGTPQPSRPGSPTGPPEVITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPELLEAEAPEAYPVFEPVPSVPEAAQGDTEDSEGAPPLKRICPNAPDP
Protein: EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) (Q9VQB7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains. Involved in epithelial cell adhesion/interaction with the extracellular matrix by mediating glycosylation of proteins in the secretory pathway, such as Dumpy (Dp).
Subcellular location: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:22158438}.
Interaction partners:
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- protein O-GlcNAcase
- Dystroglycan 1
- GDP-fucose protein O-fucosyltransferase 1
- Protein O-mannosyl-transferase 2
- Protein O-mannosyltransferase 1
- Neurogenic locus Notch protein
Sequence:
MPILPILIGILHLSLAEDAKHLDGFSLPSLPSEHLIRYLNTFPKLKQQLPTNLTGKGTISSACWGHERDCTPAGRFQTPQCPGEHTGWARSKEAQVRTFYNQADFGYIQEQLSQLTPQCVPTYLGDSSLECTHYLRFCRGRNLLFDFRGLEQREERIRYHMDVLGPGQLLGHCKLNRTRLSGEMEHIGSALQSWGPELRNFDVLPHPVLESGLCDVVVNTPTFIMKIDATYNMYHHFCDFFNLYASLFVNQSHPAAFNTDVQILIWETYPYDSPFRDTFKAFSQRPVWTLSDVEGKRVCFKNVVLPLLPRMIFGLFYNTPIIQGCSNSGLFRAFSEFILHRLQIPYKPPQQKIRITYLSRRTKYRQVLNEDELLAPLEANDKYDVQRVSYERLPFTNQLAITRNTDILIGMHGAGLTHLLFLPNWACIFELYNCEDPNCYKDLARLRGVRYRTWEQRDLVYPQDEGHHPEGGAHAKFTNYSFDVKEFVHLVDGAAEEILSHKEFPRRASENPSKTQRNEL
Protein: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.-.-) (E0SIF4)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Interaction partners:
- Achromobactin siderophore NIS synthase
- Achromobactin siderophore NIS synthase
Sequence:
MLRTNQLKRKLAAGTPVYGLIASIPSPVSVELIAEAGFDFVIIDTEHVLINPETVENMIRVAESYALTPLVRVADANPKTMLRLLDGGAQGIVLPMVEQVDQVRAAVRACHYHPQGERSLNSGRPGAFGKHSLAEYVALANREIMLVAMIESAEGVRQADAIAGVAGLDMILEGAADLSQSLGMPWQTAAPPVQAALAEVRRAADAHGVTYCAIPRQHDDHARWREQGVHAFVLGDERGIAFRALQARLAATISAEGK
Protein: Neurotrophin receptor-interacting factor 2 (Zinc finger protein 369) (Q921B4)
Organism: Mus musculus (Mouse)
Function: Transcription regulator which may participate in NGFR/p75(NTR)-mediated apoptosis. Probably acts as a transcription repressor: specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11750124}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187, ECO:0000269|PubMed:11750124}.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 16
- Neurotrophin receptor-interacting factor 1
- TNF receptor-associated factor 6
Sequence:
MASTLPTTWPHESVKFEDVSLRFTEEEWALLDRQQKCLYREIMMENLNNMISVEHHFSKANVMPQLEEVEDCWPMQREIPQDTLPECSGHSLDPEMNSFPAESPLMKIKVVEVLTLNKDMAGPRNALIQSLYPESGEDLNPGNLKPAQQPSKHLTDTEASRQKFRHFQYEESAGPQKSVSQLRKLCHQWLQPSTRSKKQILELLVLEQFLNALPEKLRVWVESQHPEDCKAVVALLENMTSVSKDDAWLACSSEATDELKEKRKDVATLPVTVPPEAPVTFQDVAVDFSQEEWQLLGPMQRTKYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNPKDLSRNRTQSTLFESISPDEVQGRHTIESNPVGLLQEKGHPQQKLSESSKSQNQTCIDKSQCSLNEVLPRNHVKVKQKGTGKGKGRTNTISMTGGLRIRNQQKDSVEWRDRSGSTPVTHGSSIKNQQLGSEQGKTQTSRDPITLTVPAEFYQEATGSEEGRFRNSSNAMAADAPPKIHQKGPEWHKAGKSNNSMLQGSSAQNHQMGSRAGRARDNSILTHVKIHQKGYKEGKIQGNNNYLKHVKPHRKGSKEERLRELSTCQKHVPYVKQHLKTSGRGKGRKINASIKCGPYIKTYYRGSDVGRLRRANNCRKAISRHAQQISFIKIHKGSQVCQCSECGKMFRNARYFSVHKKIHTGERPYMCMSCGKAFVQSSSLTQHLRIHSGERPFECSECGRTFSDRSAASQHLRTHTGAKPYQCQHCGKAFRQSSHLTRHVRIHTGERPYVCTKCGKAFTQSSNLIGHQKTHRKKFKKQPKL
Protein: Homeobox protein HMX3 (Homeobox protein H6 family member 3) (Homeobox protein Nkx-5.1) (P42581)
Organism: Mus musculus (Mouse)
Function: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MPEPGPDASGTASAPPPQPPPQPPAPKESPFSIRNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATTATPGSEDWKAGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV
Protein: Calcium-transporting ATPase 2, endoplasmic reticulum-type (EC 7.2.2.10) (O23087)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to an endomembrane compartment.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- NC domain-containing protein-like protein
- AT4g00920 protein
- Putative clathrin assembly protein At4g02650
- Wall-associated receptor kinase-like protein
- Putative clathrin assembly protein At1g03050
- Putative clathrin assembly protein At5g57200
- ATPase, F1 complex, OSCP/delta subunit protein
- Uncharacterized protein At4g00950
- F-box protein At4g00893
- Putative clathrin assembly protein At5g35200
Sequence:
MEEEKSFSAWSWSVEQCLKEYKTRLDKGLTSEDVQIRRQKYGFNELAKEKGKPLWHLVLEQFDDTLVKILLGAAFISFVLAFLGEEHGSGSGFEAFVEPFVIVLILILNAVVGVWQESNAEKALEALKEMQCESAKVLRDGNVLPNLPARELVPGDIVELNVGDKVPADMRVSGLKTSTLRVEQSSLTGEAMPVLKGANLVVMDDCELQGKENMVFAGTTVVNGSCVCIVTSIGMDTEIGKIQRQIHEASLEESETPLKKKLDEFGSRLTTAICIVCVLVWMINYKNFVSWDVVDGYKPVNIKFSFEKCTYYFKIAVALAVAAIPEGLPAVITTCLALGTRKMAQKNAIVRKLPSVETLGCTTVICSDKTGTLTTNQMSATEFFTLGGKTTTTRVFSVSGTTYDPKDGGIVDWGCNNMDANLQAVAEICSICNDAGVFYEGKLFRATGLPTEAALKVLVEKMGIPEKKNSENIEEVTNFSDNGSSVKLACCDWWNKRSKKVATLEFDRVRKSMSVIVSEPNGQNRLLVKGAAESILERSSFAQLADGSLVALDESSREVILKKHSEMTSKGLRCLGLAYKDELGEFSDYSSEEHPSHKKLLDPSSYSNIETNLIFVGVVGLRDPPREEVGRAIEDCRDAGIRVMVITGDNKSTAEAICCEIRLFSENEDLSQSSFTGKEFMSLPASRRSEILSKSGGKVFSRAEPRHKQEIVRMLKEMGEIVAMTGDGVNDAPALKLADIGIAMGITGTEVAKEASDMVLADDNFSTIVSAVAEGRSIYNNMKAFIRYMISSNVGEVISIFLTAALGIPECMIPVQLLWVNLVTDGPPATALGFNPADIDIMKKPPRKSDDCLIDSWVLIRYLVIGSYVGVATVGIFVLWYTQASFLGISLISDGHTLVSFTQLQNWSECSSWGTNFTATPYTVAGGLRTIAFENNPCDYFTLGKVKPMTLSLTVLVAIEMFNSLNALSEDNSLLTMPPWRNPWLLVAMTVSFALHCVILYVPFLANVFGIVPLSFREWFVVILVSFPVILIDEALKFIGRCRRTRIKKKIKTM