wanglab/gogpt-training-data huggingface dataset:
Protein: Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase) (Q00667)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Maleylacetoacetate isomerase
- 4-hydroxyphenylpyruvate dioxygenase
- Fumarylacetoacetase
- Xylose isomerase-like TIM barrel domain-containing protein
- homogentisate 1,2-dioxygenase
- Fumarylacetoacetase
- homogentisate 1,2-dioxygenase
- Fumarylacetoacetase
Sequence:
MPVTEFSFKDPYTYQNGFDSYHESEAIEGALPVGHNSPQKAPYGLYAEKLSGTAFTAPRHENKQTWVYRILPAAAHENFVEEDASSYHTLSDAKKLQHIPNQLRWDPFDLDETVDWVHGLHLVAGSGDPTVKQGLGILLYAAGKDMGKEAFYSADGDFLIVAQHGVLDIQTELGRLLVRPNEICVIPRGVRYRVTLPDGPVRGYICELYQGHYQLPELGPIGSNGLANARDFQAPVAAFDDEEGPTEYRLYSKFNNHLFSARQDHTPFDIVAWHGNYYPYKYDLGRFNTMGSVSFDHPDPSIYTVLTGPSDHVGTAIADFVIFPPRWLVAEKTFRPPWYHRNTMSEFMGLITGNYDAKTGGGFQPAGASLHNIMSAHGPDMHAFEGASNADLKPTKIGDGSMAFMFESSLMVGVSEWGLKTCQKVQEEYNEHSWQPLKRHFKDPRKAQ
Protein: HTH-type transcriptional regulator IscR (P0AGK8)
Organism: Escherichia coli (strain K12)
Function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. Transcriptional repressor of the iscRSUA operon, which is involved in the assembly of Fe-S clusters into Fe-S proteins. In its apoform, under conditions of oxidative stress or iron deprivation, it activates the suf operon, which is a second operon involved in the assembly of Fe-S clusters. Represses its own transcription as well as that of toxin rnlA.
Interaction partners:
- Cysteine desulfurase IscS
- Iron-sulfur cluster assembly scaffold protein IscU
- Co-chaperone protein HscB
- Iron-binding protein IscA
- Chaperone protein HscA
- 2Fe-2S ferredoxin
- Protein IscX
- Fe/S biogenesis protein NfuA
- Iron-sulfur cluster insertion protein ErpA
- Redox-sensitive transcriptional activator SoxR
Sequence:
MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKLRA
Protein: LP10213p (Q5BI58)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
LGVHRRQTKLSNRNLNYGRRGRSRRGGGEYVSGTIITMRTMPAHPHQIPVFLSKNLRDSLYLFQYPTKTELPNHDDSVIVNCCVKPIAQEVKVDFGLDIESAHFDRFKGEQFAVAADGKNTYGAVPPKGQERPTYKRGIMDKQAFTSSRSITDVAKYIVGIFTDREVHLSPLTSIVQMRPVLSHFDKDDKRKKAELKAQTEDTDDDEVLQQVTVKFARGNAKNSGKEQRVGTYDSFVQRIADEPWCEAYWHSRGTPTAELERKKLFATSHHGSSSLALAPDEYLRKLLPYDEHVQTVAPAAASAAAQVLPVYNKAMLKSMPLLEQLTVLLRDARMLSFSDVISILAEHVDPHVAADKVLALLPQVGILLHGNWVPKSEVVFPEKVLSHANGVSAEQMIRARDYILFRFSRTPYLFRAQVMAATQLPPAETLDVLKTVARVNNTKRWELLLPPDKEFEQKYPELVSRQEYHWTASEQHYNEMDWARETKRVRKRSTRKSESQSLTSAMPPPAMNHSTTGSVDA
Protein: Transcriptional regulatory protein moc3 (Multicopy suppressor of overexpressed cyr1 protein 3) (Q9UT46)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Induces sexual development and ascus formation. Also involved in calcium homeostasis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227, ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16273369, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Ataxin-10 homolog
- Protein sds23/moc1
Sequence:
MNPYVSYPEIHMKRNRTGSINSNPLYIPNPNVEPTPKPTKRRTKTGCLTCRRRRIKCDETKPFCLNCTKTNRECEGYPNSAAQMQAMGSVSPPELSVHSAQQPLIPTSIASSSAQTGDTFSGSSQSNFNTNDLNQMTSSSNLSTVTPIKQDHQKPMNLQGFPSAYQQHQYLQSNHNVPTNNSSSATSSTKPSVQSVGQASYPFLSSVSNFPSNFNSELFPFYFHDVVPSICAFEFDNNIALHFWSVTVPQFAQSMPCIANSLMAFASIKKLDVFGAYSHLTRALRCPMPGPNSFEYLLVSAFLTLTQLNLPAYDLNFCNNFIRKLSWSSSTKSNYVSLLIAMVVRELVFAILPRGCIWGFNGKPLSEVSVSRSHAPVSDSLFTIGLDILSQPTLSDDLHRERMVAWRDEYHVHLYSASRSPLTKVIDCVGHAVTKNNNDVLSGLQQLMQEECTDIAVLRTSYLCVLSLQNVFASNSKEFKLRAQIESHFGRLMLEHFMDCNVLNRPVL
Protein: Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase) (Q99JF5)
Organism: Mus musculus (Mouse)
Function: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12736493}.
Interaction partners:
- Mevalonate kinase
- Farnesyl pyrophosphate synthase
- Isopentenyl-diphosphate Delta-isomerase 1
- Phosphomevalonate kinase
- Geranylgeranyl pyrophosphate synthase
- Isopentenyl-diphosphate delta-isomerase 2
- Lanosterol synthase
- Hydroxymethylglutaryl-CoA synthase, cytoplasmic
- Squalene monooxygenase
- Squalene synthase
Sequence:
MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTVAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTEDGDTLPLSLSYKVHVASVNNFPTAAGLASSAAGYACLAYTLAQVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRILILVVSADKKQTGSTVGMQTSVETSTLLKFRAESVVPERMKEMTRCIQEQDFQGFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNTHQGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKAALAVEPSPGGVQYIIATQVGPGPQVLDDTHDHLLGQDGLPQRDL
Protein: E3 ubiquitin-protein ligase ORTHRUS 5 (EC 2.3.2.27) (Protein VARIANT IN METHYLATION 2) (RING-type E3 ubiquitin transferase ORTHRUS 5) (Q680I0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase. Participates in CpG methylation-dependent transcriptional regulation and epigenetic transcriptional silencing. Mediates ubiquitination with the E2 ubiquitin-conjugating enzyme UBC11.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00358, ECO:0000269|PubMed:18704160}. Note=Broadly distributed in the nucleus and enriched in the heterochromatic chromocenters.
Interaction partners:
- DNA
- DNA
- DNA
- Reverse transcriptase-like protein
- Alpha/beta-Hydrolases superfamily protein
- DNA
- Endoglucanase 20
Sequence:
MAIQTQLPCDGDGVCMRCQVNPPSEETLTCGTCVTPWHVSCLLPESLASSTGDWECPDCSGVVVPSAAPGTGISGPESSGSVLVTAIRAIQADVTLTEAEKAKKRQRLMSGGGDDGVDDEEKKKLEIFCSICIQLPERPVTTPCGHNFCLKCFEKWAVGQGKLTCMICRSKIPRHVAKNPRINLALVSAIRLANVTKCSGEATAAKVHHIIRNQDRPDKAFTTERAVKTGKANAASGKFFVTIPRDHFGPIPAANDVTRNQGVLVGESWEDRQECRQWGVHFPHVAGIAGQAAVGAQSVALSGGYDDDEDHGEWFLYTGSGGRDLSGNKRVNKIQSSDQAFKNMNEALRLSCKMGYPVRVVRSWKEKRSAYAPAEGVRYDGVYRIEKCWSNVGVQGLHKMCRYLFVRCDNEPAPWTSDEHGDRPRPLPDVPELENATDLFVRKESPSWGFDEAEGRWKWMKSPPVSRMALDTEERKKNKRAKKGNNAMKARLLKEFSCQICRKVLSLPVTTPCAHNFCKACLEAKFAGITQLRDRSNGVRKLRAKKNIMTCPCCTTDLSEFLQNPQVNREMMEIIENFKKSEEEAEVAESSNISEEEGEEESEPPTKKIKMDKNSVGGTSLSA
Protein: Protein ALWAYS EARLY 2 (AtALY2) (Q6A333)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Retinoblastoma-related protein 1
- Histone-binding protein MSI1
- Transcription factor E2FC
- Transcription factor-like protein DPA
- Transcription factor-like protein DPB
- Paired amphipathic helix protein Sin3-like 4
- Transcription factor MYB3R-3
- Protein ALWAYS EARLY 3
- Protein ALWAYS EARLY 1
- Paired amphipathic helix protein Sin3-like 5
Sequence:
MAPVRKSRSVNKRFTNETSPRKDAGKSKKNKLRKKLSDKLGPQWTRLELERFYDAYRKHGQEWRRVAAAIRNSRSVDMVEALFNMNRAYLSLPEGTASVAGLIAMMTDHYSVMEGSGSEGEGHDASEVPRKQQKRKRAKPQRSDSPEEVDIQQSIGSPDGCLTFLKQARANGTQRHATGKRTPRVPVQTSFMRDDREGSTPPNKRARKQFDANDDVAHFLALALTDASRRGGSPKVSESPNRRTELSDSSPIKSWGKMSRTRKSQSKHCGSSIFEEWMESSRERKLDSDKDTTLLMDMERAGEMEAPRKGKRVYKKRVKVEEAECNDSDDNGEACSATQGLRSKSQRRKAAIEASREKYSPRSPKKRDDKHTSGAFDALQALAELSASMLPANLMESELSAQLKEERTEYDMDEKSSTPEATSTSSHGEKANVEPDDSLLHAISSVENANKRKSKPSRLVSTDCDDVPTGKLQPQTSGSLRKRKPKVLGDEAPAEFSQNKSINKKELPQDENNMKSLVKTKRAGQVPAQSKQMKTVKALEESAITSDKKRPGMDIVASPKQVSDSGPTSLSQKPPNRRKKSLQKSLQEKAKSSETTHKAARSSRSLSEQELLLKDKLATSLSFPFARRRCIFEWFYSAIDHPWFSKMEFVDYLNHVGLGHIPRLTRLEWSVIKSSLGRPRRFSERFLHEEREKLKQYRESVRKHYTELRTGAREGLPTDLARPLAVGNRVIAIHPKTREIHDGKILTVDHNKCNVLFDDLGVELVMDIDCMPLNPLEYMPEGLRRQIDKCLSMKKEAQLSGNTNLGVSVLFPPCGLENVSFSMNPPLNQGDMIAPILHGKVSSNTSSPRQTNHSYITTYNKAKEAEIQRAQALQHALDEKEMEPEMLEIVKGSKTRAQAMVDAAIKAASSVKEGEDVNTMIQEALELVGKNQLLRSSMVKHHEHVNGSIEHHHNPSPSNGSEPVANNDLNSQDGSEKNAQMPSELITSCVATWLMIQMCTERQYPPADVAQLIDAAVTSLQPRCPQNLPIYREIQTCMGRIKTQIMSLVPT
Protein: Chaperone protein DNAJ, putative (Q4GYE8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
Sequence:
MAHISVTDTHFRVLGIPRGCDETALRKAFRQKALDLHPDRNPNGADEFKKVNEAYEALQQHFRRNGGRDVLPHAPPSNAGTGFQYARQAREPPCHFTEEELFGCSPGGFSHERRGYGAKCYARFGGRRWQASGNSGDNNVGGGIDLDGGSMPFGGFPVGSKEEHQRVDERWRQAHGRRVPVSGYSYARGGAASCHARSHPFSHNHNQQQQQQQQRPPQSSSPPFNGASGSPMTEPKPNGGEKARGTGEGSSSAGGGAAGSNDKSYTHASSSPPSYDGSYTQQPNEKRMSSDELYREWERLMREFDSKTSATGGAFRDPCEWEWDNSDTSVVSDGEDSQDTDDDDNDDDDGEENYVVNKKKHPASSSSRRARTCSSRFSERNRLNETHMRSIIEEKIQLKKILFTQRYTPDPADVALMSDNEVYVLCEVLRDVEQRMQKVLVGRLTKGLCSRCMKAPKMQGSKLFTCGHASVCSECACTCAVCPICAATSRR
Protein: LD15094p (Q8MRJ0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVQKYYEVMAKVDWVADELQLEHRLHQVYGLVRNKFRNYAMNALETADMYREAKTKFVFDPEVGIIDLEQKLPMSWHAFNETPRFEEIPEYQVLAKAQSFFSETNSSIVMKLYNMRTHLDPKTWLPPYYSRALLIDSRHYMTFDQRYVGLNLNFDELGNGRSTSQCSYLLAHDFFKRNFTLLLEPASKSLAGQGLTRKLSFIANGQLIEIDLETDHISINGNPQPILPLKLGDVNIHRDLDVLSITSDTEFSLHCNVQFDLCWFEVSGWYFGRTAGLLGTLNNEPYDEYTMSSGVISNETQLFTDSWSLKQCRQNKLAQTQEVSQEVSDACTSFFRTGILATCSAVLDPTPFYEMCMDLGMKSPPIRKGHPAVKGACAAALAYIEACTALKVPMRVPSQCVFCQLSNGSYVPEGTFMELSGPEIPKSSDVVFIVEAKECNANLKTSKNIMTVVSSIEEQLQAAKITNNRYAVVAFGGVSPYDKARSVIYEHNEFTSKPEQLADYFGHINTGNGSSNDILMAISAAAKLNFRPGVSKTFILLSCSKCAARDMRFDYTSILQYLLEEGVNLHILADTEFDFERNKKLRHFFGLDSKLVYSKRFPEGDAETRNTTHIPKSNLGICTTLAVETQGSVFSARKLQPERKYPIKRFATIFAKRVALSATPIQSQTCECSAHNTGVSYMACSPQALPEEKYDLDDYDSFNNWDWGDEPESETNVMS
Protein: X-ray repair cross complementing 4 (A0A8I5Y5Z6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPRHSESVIGFCYRKRSSEMERKVSRISLASEPNVTYFLQVSWEGTIGSGFVITLTDGHSAWTAKVSESEIAQEADDMAMEQEKYMDELRRALVPESGAAGAYKFIFSKDTQHFSLEKELKDVSFRLGSFNLDKVTNPTEVIRELICYCLDTIAEKQAKNEHLQKENERLLRDWTDVQGRFEKCVSDKEALEADLYQRFILVLNEKKTKIRSLLSEVQQLEKSTKPERETPSSDKIPEEDGLYDGSTDEESGAPVLGADTLDKDDSLFSSPDVTDIAPSRKRRHRMQTNLGTEPKMAPQELPLQEKERLGSSPPQTLKEEGTSAAKMSLETLRNSSPEDLFD
Protein: SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP) (Q5HYK7)
Organism: Homo sapiens (Human)
Function: May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14551139}. Nucleus {ECO:0000269|PubMed:14551139}. Note=Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein.
Interaction partners:
- SH3 domain-containing YSC84-like protein 1
- Clathrin interactor 1
- Pumilio homolog 1
- Zinc finger protein 687
Sequence:
MNIMNTEQSQNSIVSRIKVFEGQTNIETSGLPKKPEITPRSLPPKPTVSSGKPSVAPKPAANRASGEWDSGTENRLKVTSKEGLTPYPPLQEAGSIPVTKPELPKKPNPGLIRSVNPEIPGRGPLAESSDSGKKVPTPAPRPLLLKKSVSSENPTYPSAPLKPVTVPPRLAGASQAKAYKSLGEGPPANPPVPVLQSKPLVDIDLISFDDDVLPTPSGNLAEESVGSEMVLDPFQLPAKTEPIKERAVQPAPTRKPTVIRIPAKPGKCLHEDPQSPPPLPAEKPIGNTFSTVSGKLSNVERTRNLESNHPGQTGGFVRVPPRLPPRPVNGKTIPTQQPPTKVPPERPPPPKLSATRRSNKKLPFNRSSSDMDLQKKQSNLATGLSKAKSQVFKNQDPVLPPRPKPGHPLYSKYMLSVPHGIANEDIVSQNPGELSCKRGDVLVMLKQTENNYLECQKGEDTGRVHLSQMKIITPLDEHLRSRPNDPSHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVIIDIPEGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQIS
Protein: Putative protein FAM10A4 (Suppression of tumorigenicity 13 pseudogene 4) (Q8IZP2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MDPRKVNELRAFVKMCKKDPSILHTQEMRFLREWVESMGGTATQKAKSEENTKEEKPDSKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEVMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKRRGKAHRLLGHWEEAAHDLALACKFDYDEDASAMLKEVQPRAQKIAEHQRKYERKREE
Protein: Ras-related protein Rac1 (AjRac1) (A0A286QZ36)
Organism: Stichopus japonicus (Sea cucumber)
Function: Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P63000}; Lipid-anchor {ECO:0000250|UniProtKB:P63000}; Cytoplasmic side {ECO:0000250|UniProtKB:P63000}.
Interaction partners:
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRTKWYPEVSHHCPSTPIILVGTKLDLRDDKETMNKLSERSLRPIAYPQGLQMQKEIHAVKYLECSALTQKGLKTVFDEAIRAVLCPPAKNKSKRSCQLL
Protein: Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein) (A2ACR0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLGGMLTRQPFAIGGSGSTFI
Protein: Holliday junction resolvase (EC 3.1.-.-) (Q9J546)
Organism: Fowlpox virus (strain NVSL) (FPV)
Function: Nuclease that specifically cleaves and resolves four-way DNA Holliday junctions into linear duplex products.
Interaction partners:
Sequence:
MIICSVDIGIKNPAYAIFNYDNTSNTIKLIAIEKSDWTKNWERSVARDLTRYNPDVVILEKQGFKSPNSKIIYFIKGFFYNSNTKVIVRNPTFKGGSYRNRKKQSIDVFIQKISEYTDYKNDILNKYTKLDDIADSFNLGLSYMESLLKKCKISKD
Protein: Uncharacterized protein YmfJ (P75973)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Prophage excisionase-like protein
- Uncharacterized protein YmfL
- Prophage integrase IntE
- Prophage transcriptional regulatory protein
- Uncharacterized protein YmfM
- Uncharacterized protein YmfI
- Uncharacterized protein YmfE
- Uncharacterized protein StfP
- Uncharacterized protein YmfR
- Prophage repressor CohE
Sequence:
MNEQNLKHVIALLLEDAKRLQQIEPNAGTEARILLAKQALKTCGAQAPGRTEFMNFMANTLTPLPCNGEKVSRVYHDTMVKALRIELDGLRRKIVMNEIVTN
Protein: Pumilio homolog 12 (APUM-12) (AtPUM12) (Q9LVC3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20214804}. Nucleus {ECO:0000269|PubMed:20214804}.
Interaction partners:
- Pumilio homolog 26
- Pumilio homolog 24
- Pumilio homolog 23
- Putative receptor-like protein kinase At2g30940
- F28K20.8 protein
- At1g31240
- Probable acyl-activating enzyme 9
- HVA22-like protein j
- MEI2 C-terminal RRM only like 2
- At3g14700
Sequence:
MDQRRGNELDEFEKLLGEIPKVTSGNDYNHFPICLSSSRSQSIKKVDQYLPDDRAFTTSFSEANLHFGIPNHTPESPHPLFINPSYHSPSNSPCVYDKFDSRKLDPVMFRKLQQVGYLPNLSSGISPAQRQHYLPHSQPLSHYQSPMTWRDIEEENFQRLKLQEEQYLSINPHFLHLQSMDTVPRQDHFDYRRAEQSNRNLFWNGEDGNESVRKMCYPEKILMRSQMDLNTAKVIKYGAGDESQNGRLWLQNQLNEDLTMSLNNLSLQPQKYNSIAEARGKIYYLAKDQHGCRFLQRIFSEKDGNDIEMIFNEIIDYISELMMDPFGNYLVQKLLEVCNEDQRMQIVHSITRKPGLLIKISCDMHGTRAVQKIVETAKREEEISIIISALKHGIVHLIKNVNGNHVVQRCLQYLLPYCGKFLFEAAITHCVELATDRHGCCVLQKCLGYSEGEQKQHLVSEIASNALLLSQDPFGNYVLQYVFELQLQWATFEILEQLEGNYTELSMQKCSSNVVEKCLKLADDKHRARIIRELINYGRLDQVMLDPYGNYVIQAALKQSKGNVHALLVDAIKLNISSLRTNPYGKKVLSALSSKK
Protein: Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3) (O70137)
Organism: Mus musculus (Mouse)
Function: Transcriptional regulator with a possible role in patterning of mesoderm during development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MDPERCAPFSVGPAAGPYAAAGDEAPGPQGTPDAAPHLHPAPPRGPRLSRFPACGPLEPYLPEPAKPPAKYLQDLGPGPVLNGGHFYEGSAEAEEKASKAASFPQLPVDCRGGPRDGPSNVQASPGPCLASLSVPLSPGLPDSMELAKTKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKMQEGRNPFTTAYDISVLPRTDSHPQLQNSLWPSPGSGSPGGPCLMSPEGIPSPCMSPYSHSHGNVAGFMGVPASPAAHPGIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPPGLLNWTT
Protein: Diacylglycerol kinase 7 (AtDGK7) (DAG kinase 7) (EC 2.7.1.107) (Diglyceride kinase 7) (DGK 7) (F4JQ95)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress xhibits high specificity for 1,2-dioleoyl-sn-glycerol (1,2-DOG), 1-palmitoyl, 2-oleoyl-sn-glycerol (1,2 POG), 1-stearoyl, 2-linoleoyl-sn-glycerol (1,2-SLG) and 1-oleoyl, 2-palmitoyl-sn-glycerol (1,2-OPG).
Interaction partners:
- Sulfoquinovosyl transferase SQD2
- Choline/ethanolaminephosphotransferase 1
- Choline/ethanolaminephosphotransferase 2
- Putative phospholipid:diacylglycerol acyltransferase 2
- Phospholipid:diacylglycerol acyltransferase 1
- Triacylglycerol lipase SDP1L
- Triacylglycerol lipase SDP1
- Phosphoinositide phospholipase C 5
- 1-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic
- Non-specific phospholipase C6
Sequence:
MEETPRSVGEASTTNFVAARPSAKTDDAVTMRGCGFANLALVGIDKEELRGRLAMPEYLRIAMRDCIKRKDSTEISDHLLLPGGAAADMAPHAPMVVFINPKSGGRHGPVLKERLQQLMTEEQVFDLTEVKPHEFVRYGLGCLDTLAAKGDECARECREKIRIMVAGGDGTVGWVLGCLGELHKDGKSHIPPVGVIPLGTGNDLSRSFSWGGSFPFAWRSAMKRTLHRATLGSIARLDSWKIVVSMPSGEVVDPPYSLKPTIEETALDQALDADGDVPPKAKSYEGVFYNYFSIGMDAQVAYGFHHLRNEKPYLAQGPVTNKIIYSSYSCTQGWFCTPCVNNPALRGLRNIMKIHIKKANCSEWEEIHVPKSVRSIVVLNLYNYGSGRHPWGNLRPKYLEKRGFVEAHCDDGLIEIFGLKQGWHASFVMAEIISAKHIAQAAAIRFELRGGDWKNAFLQMDGEPWKQPMKSDYSTFVEIKKVPFQSLMINGE
Protein: Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1) (Q8K4K5)
Organism: Rattus norvegicus (Rat)
Function: Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane.
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:21856246}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:21856246}. Golgi apparatus membrane {ECO:0000269|PubMed:21856246}. Cell projection, axon {ECO:0000269|PubMed:21856246}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localized to the lateral membrane during the polarization and formation cell-cell contacts (By similarity). Enriched in developing axons. {ECO:0000250}.
Interaction partners:
- LLGL scribble cell polarity complex component 2
- Protein kinase C zeta type
- Protein kinase C iota type
- Disks large homolog 4
- Protein scribble homolog
- Disks large homolog 1
- Disks large homolog 3
- Ubiquitin-protein ligase E3A
- Disks large homolog 2
- Disks large homolog 5
Sequence:
MMKFRFRRQGADPQREKLKQELFTFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLPGQGRLLTLLDDSSLHLWEIIQRNGCAHLEEGLSFHPPSRPSFGNASFPAGLTRVTVVLLAAGDTVVLGTESGSIFFLDVATLALLEGQTLSPDEVLRSVPDDYRCGKALGPVESLQGHLQDPSKILIGYSRGLLVIWSQATQSVEHVFLGNQQLESLCWGRGGSNIISSHSDGSYAIWSTDTGSPPTLQPTVVTTPYGPFPCKAINKILWRSCESGDHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRVIDFFTVHSTQPEDGFDNPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPSKLWARIVSAGERQSPQPASSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEHADSLAQAVEDDWPPFRKVGCFDPYSDDPRLGIQKVALCKYTAQMVVAGTAGQVLVLELSDVPGEHTVSVASVDLLQDREGFTWKGHERLSPHTGPLPWPAGFQPRVLIQCLPPAAVTAVALHAEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRATTASSKLQEANAQLAEQTCPHDVEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDATHHGPTMWAGTNSGSVFAYALEVPAATAGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVMSEDYAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDISWPQNATQPRLQESPKLSQANGTRDIILAPESCEGSPSSAHSKRADTMEPPEAALSPVSIDSAASGDTMLDTTGDVTVEYVKDFLG
Protein: Glycerol kinase (GK) (Glycerokinase) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (P32190)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- Glycerol-1-phosphate phosphohydrolase 1
- Glycerol 2-dehydrogenase
- Glycerol-1-phosphate phosphohydrolase 2
- Glycerol-3-phosphate O-acyltransferase 2
- Glycerol-3-phosphate O-acyltransferase 1
- Monoglyceride lipase
- NADP-dependent alcohol dehydrogenase 7
- NADP-dependent alcohol dehydrogenase 6
- Potassium-activated aldehyde dehydrogenase, mitochondrial
Sequence:
MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSDYVPLIASIDVGTTSSRCILFNRWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARETPNAGDIKTSGKPIFSAEGYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTINSERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNYGIVWNDTRTIKIVRDKWQNTSVDRQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLTKQKAFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIPDWIMEKLHDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAFWFPHLQEYGGQKPELSKPHFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILGPCVKVRRSPTAECTALGAAIAANMAFKDVNERPLWKDLHDVKKWVFYNGMEKNEQISPEAHPNLKIFRSESDDAERRKHWKYWEVAVERSKGWLKDIEGEHEQVLENFQ
Protein: Btbd2 protein (Q91YK4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
KVLGKALSLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
Protein: Fatty acid-binding protein 5 (Cutaneous fatty acid-binding protein) (C-FABP) (DA11) (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein, epidermal) (P55053)
Organism: Rattus norvegicus (Rat)
Function: Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (By similarity). Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q05816}. Nucleus {ECO:0000250|UniProtKB:Q01469}. Synapse {ECO:0000250|UniProtKB:Q05816}. Postsynaptic density {ECO:0000250|UniProtKB:Q05816}. Secreted {ECO:0000250|UniProtKB:Q05816}. Note=Localizes primarily to the cytoplasm. Upon certain ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into nucleus (By similarity). Secreted by astrocytes, but not by neurons (By similarity). {ECO:0000250|UniProtKB:Q01469, ECO:0000250|UniProtKB:Q05816}.
Interaction partners:
- Gastrotropin
- Fatty acid-binding protein, liver
- Fatty acid-binding protein, adipocyte
- Fatty acid-binding protein, heart
- Fatty acid-binding protein, brain
- Peroxisome proliferator activated receptor delta, isoform CRA_b.
- Aspartate aminotransferase, mitochondrial
- Fatty acid-binding protein, intestinal
Sequence:
MASLKDLEGKWRLVESHGFEDYMKELGVGLALRKMGAMAKPDCIITLDGNNLTVKTESTVKTTVFSCTLGEKFDETTADGRKTETVCTFTDGALVQHQKWEGKESTITRKLKDGKMVVECVMNNAICTRVYEKVQ