wanglab/gogpt-training-data huggingface dataset:
Protein: Putative uncharacterized protein BUD28 (Q07992)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Putative uncharacterized protein YGL217C
- Putative uncharacterized protein YLR125W
- Uncharacterized protein YMR182W-A
Sequence:
MNLFFVFFFVFFWSDLVEGQSVFVGLGRDKSDPVSQLVLLQVLLCQVLQVLTRELGSGNNSNNGTIFSDSDSVTQVTDSTFDLDVVDQVLSVGSWVEDTVFSWRRDIDGKGLGNLLLSGSLYQKN
Protein: Probable xyloglucan 6-xylosyltransferase 5 (EC 2.4.2.39) (Putative glycosyltransferase 5) (AtGT5) (EC 2.4.-.-) (Q9CA75)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable xyloglucan xylosyltransferase involved in the biosynthesis of xyloglucan in roots. May act in association with XXT1 and XXT2. Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:18557833, ECO:0000269|PubMed:22665445, ECO:0000269|PubMed:25392066}; Single-pass type II membrane protein {ECO:0000305|PubMed:25392066}.
Interaction partners:
- Xyloglucan galactosyltransferase MUR3
- Xyloglucan glycosyltransferase 4
- Galactoside 2-alpha-L-fucosyltransferase
- Xyloglucan galactosyltransferase XLT2
- Polygalacturonate 4-alpha-galacturonosyltransferase
- Probable starch synthase 4, chloroplastic/amyloplastic
- Probable galacturonosyltransferase 7
- Probable arabinosyltransferase ARAD1
- Trihelix transcription factor GT-1
- Probable arabinosyltransferase ARAD2
Sequence:
MGQDGSPAHKRPSGSGGGLPTTTLTNGGGRGGRGGLLPRGRQMQKTFNNIKITILCGFVTILVLRGTIGVGNLGSSSADAVNQNIIEETNRILAEIRSDSDPTDLDEPQEGDMNPNATYVLGPKITDWDSQRKVWLNQNPEFPSTVNGKARILLLTGSPPKPCDNPIGDHYLLKSVKNKIDYCRLHGIEIVYNMAHLDKELAGYWAKLPMIRRLMLSHPEVEWIWWMDSDALFTDILFQIPLARYQKHNLVIHGYPDLLFDQKSWIALNTGSFLLRNCQWSLDLLDAWAPMGPKGPIRDEAGKVLTAYLKGRPAFEADDQSALIYLLLSQKDTWMEKVFVENQYYLHGFWEGLVDRYEEMIEKYHPGLGDERWPFVTHFVGCKPCGSYADYAVERCLKSMERAFNFADNQVLKLYGFSHRGLLSPKIKRIRNETVSPLEFVDKFDIRRTPVETKPQN
Protein: Flavonol 3-O-glucosyltransferase UGT76E12 (EC 2.4.1.91) (Flavonol 7-O-beta-glucosyltransferase UGT76E12) (EC 2.4.1.237) (UDP-glycosyltransferase 76E12) (Q94AB5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses quercetin 3-O-glucosyltransferase and 7-O-glucosyltransferase activities in vitro.
Interaction partners:
- Uncharacterized protein T2H7.3
- Uncharacterized protein At1g21520
- At5g11090
- Transcription regulator-like
- Probable dihydroneopterin aldolase 3
- Dihydroneopterin aldolase 1
Sequence:
MQVLGMEEKPARRSVVLVPFPAQGHISPMMQLAKTLHLKGFSITVVQTKFNYFSPSDDFTHDFQFVTIPESLPESDFKNLGPIQFLFKLNKECKVSFKDCLGQLVLQQSNEISCVIYDEFMYFAEAAAKECKLPNIIFSTTSATAFACRSVFDKLYANNVQAPLKETKGQQEELVPEFYPLRYKDFPVSRFASLESIMEVYRNTVDKRTASSVIINTASCLESSSLSFLQQQQLQIPVYPIGPLHMVASAPTSLLEENKSCIEWLNKQKVNSVIYISMGSIALMEINEIMEVASGLAASNQHFLWVIRPGSIPGSEWIESMPEEFSKMVLDRGYIVKWAPQKEVLSHPAVGGFWSHCGWNSTLESIGQGVPMICRPFSGDQKVNARYLECVWKIGIQVEGELDRGVVERAVKRLMVDEEGEEMRKRAFSLKEQLRASVKSGGSSHNSLEEFVHFIRTL
Protein: ATP synthase subunit a (Q36986)
Organism: Oryza sativa (Rice)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion inner membrane {ECO:0000256|RuleBase:RU004450}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU004450}.
Interaction partners:
Sequence:
MNFDHNHVVIMGLNQRDSIWKLLNDYNVNSLKRRRQAEIDAFFEPFERAQYRFNNWQNGIELLDGAEWRNGDIVIPGGGGPVISSPLDQFFIDPLFGLDMGNFYLSFTNESLSMAVTVVLVPSLFGVVTKKGGGKSVPNAWQSLVELIYDFVLNLVNEQIGGNVKQKFFPRISVTFTFSLFRNPQGMIPFSFTVTSHFLITLALSFSIFIGITIVGFQRHGLHFFSFLLPAGVPLPLAPFLVLLELISHCFRALSSGIRLFANMMAGHSSVKILSGFAWTMLFLNNIFYFIGDLGPLFIVLALTGLELGVAILQAHVSTISICIYLNDAINLHQNE
Protein: NADH-dependent phenylglyoxylate dehydrogenase subunit beta (EC 1.2.1.58) (Phenylglyoxylate:NAD oxidoreductase) (Phenylglyoxylate:acceptor oxidoreductase) (Q8L3A9)
Organism: Aromatoleum evansii (Azoarcus evansii)
Function: Involved in the anaerobic metabolism of phenylalanine and phenylacetate. Catalyzes the oxidative decarboxylation of phenylglyoxylate to benzoyl-CoA and CO(2). It can also react slowly with 2-oxo-3-methylbutanoate and use different electron acceptors such as benzyl viologen, methyl viologen, FAD or FMN, but NAD seems to be the physiological electron acceptor. Also catalyzes an isotope exchange between CO(2) and the carboxyl group which proves partial or complete reversibility of the oxidative decarboxylation reaction.
Interaction partners:
Sequence:
MGRAYSTIAFDPAKCDGCGDCMTACAQAKTGTDDIARSRIQIYGREGAADKTFELALCRQCADPKCVTVCPAGALNKDGTSGVIGWDATKCVDCLLCTVGCAYAGIALDEATGHVAKCDTCDGNPACVPACPHGALKHITTANIYNEVGDWEDLFAPGLAGCQGCNTELLMRHTLRRVGPDTVLATPPGCVPGMGSVGFNGTTGTKVPVFHPLLTNTAAMLAGIKRQYKRVGRDVQALAIAGDGGASDVGFQSLSGRAERGEQMLFMVVDNEGYMNTGMQRSSCTPYGAWTSTTPVGETSRGKTQDAKNLPLIMVNHRCAYVATASTAYMEDLYDKLDKAIAASKNGFAYLHVYSPCTTAWRFPSNLNMEVARKAVETNFVMLWEYTPQDGLHFTKPVDDPLPVTDYLKAMGRFRHLTPEQVEHIQKKVVENQKFVERMTEHAHVG
Protein: MutT/nudix family protein (AFU_orthologue AFUA_5G08240) (C8VDH4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- ribose-phosphate diphosphokinase
- Ribose-phosphate pyrophosphokinase
- Phosphoglucomutase
- Phosphoglucomutase, putative
- Decapping enzyme Dcp1, putative
- Topisomerase II associated protein
Sequence:
MSDPMYARSKFLSKGPLDPNEAKWTRLVKTTYCDPNGVERTWESAERQTRPANCEVDGVGIVTILDKSSGPELLLQKQYRPPIDKVVIEVPAGLIDPNETVEECAVRELKEETGYVGVADATSTVMYNDPGFCNTNLNMVHVRVDMSLPENQNPKPQLEDNEFIECFTLPLASLFDELKRLEAEGYAIDARIGTIAEGIELAKKLKL
Protein: Putative rRNA methylase (Q9XBC9)
Organism: Amycolatopsis orientalis (Nocardia orientalis)
Interaction partners:
Sequence:
MEQDVRLLHASSFGAAAASYAEHRPDYAPAAARWALEHAPGPRVLDLGAGTGKLTAALVALGAEVIAVEPDPAMLTELRRAVPTVRALPGNAEAIPLPDASIDAVLAGNALHWFDMSVAGPEIARVLAPGGILAGLWNVMDNRVDWVAGLERVGGSAAIGSRDTFSSWRAATTGLHRPHTGVAARFGSPEQAEFPHGQRRTADSLVATLATRAGLLVMPEQERRATLSRIRAFLASRPETNEGEFTLPMLTGVLRVRQL
Protein: MORC family CW-type zinc finger 2 (H7C1V1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKDIDINTDDELDAYIEDLITKGD
Protein: Nucleophosmin (E5RI98)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
MNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
Protein: Oligoxyloglucan-reducing end-specific xyloglucanase (OREX) (EC 3.2.1.150) (Q5BD38)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Oligoxyloglucan-reducing end-specific xyloglucanase involved in degradation of xyloglucans. Releases the first two glycosyl segments from oligoxyloglucans. Active against cotton xyloglucan, tamarind xyloglucan and tamarind xyloglucan oligomers (Probable).
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Probable beta-glucosidase J
Sequence:
MRAKNGPGSWLALTAIATSLNTLALAAAKTINHSYEFNPVVVSGGGYITGIIAHPTEKNLLYARTDIGGTYRWNADEDKWIPLNDFISGADENLLGTESVALDPNDPDRLYLAQGRYLNSENSAFFVSQDRGATFDVYPAPFKMGANELGRNNGERLAVNPFKTDELWMGTRDAGLMVSEDGAQTWRNVSGFPQANANGIGIYWVIFDPRSEGTVYVGVGVPGGIYVTRDSGESWEAVPGQPVEWDEDILVFPAESQPQSTGPQPMKGVLAENGALYVTYADAPGPYGVTYGGVYVYNTTSSAWTNITPKTNNSFPAPFDNQTFPAGGFCGISVDSKNPERLVVVSLDRDPGPALDSMYLSHDGGKSWKDVSQLSTPSGSGGYWGHPIEEAAFKDGTAVPWLSFNWGPQWGGYGAPSPVRGLTKFGWWMTAVVIDPSDSDHVLYGTGATIWATDNLSKVDKNQSPGWYIQAQGIEESVALALASPNGGDSHLLTGLGDINGYRYGDLDVPQPMFDLPVLSNLNALDWAGQKPEIIIRAGPCGHNYTDGCGLAAYSADGGSSWTKFATCIPGINTSSSNPGVIAIDASGKDIVWSSAMTAYWPTLQAITPRTNQSGPYVTTDLGQTWVSPTGLNVQTPNISADRVQPRTFYSFTDGTWYLSRDGGLSYRAYKAKEVGLPAYSGALPIANFNRAGEIWLGLGDHGIYHTRNFGKKWTKITGRGVTARQLTIGAGARRSSEPTLFIVGKAASHGALSKDGVYRSDDNGKTWVRVNDEKHQYGGIAMIQGDPRVYGRVYLGTGGRGIIYADIKE
Protein: Phosphodiesterase (EC 3.1.4.-) (B1AWC9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLEETDIDIATEDKSPIDT
Protein: LD36945p (Q9VK18)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSKSSAARWVKFFNAAGIPSPAAAGYAHVFVENRIQDDMLLDLNKEYLREMGITLMGDIIAILRHSKTVCEQNAREQVLTTEVVQSVVRPVSPKPKAPVATPKAKVYPPAKPARRVLPEHEGKYKVTLPSGTTERSKQILAKREKLYSDRVSSSKKSDIFTRLHAEDEAQEGIVSSSGESSVRVHVAGASKTAATSSNNSVFARLGGKQGALPEEFTSTREIKSILKNTHRTVGGGGGGGGVTKNSPIVKAKKVAAVTQQKVMLVHKVPLKKGDDDDDSMDDFESDEEDYMSSGEDFDMGAGEKIVKFASTAEVREIVPESAYKNRQGKSFANNIKSRLGMVSKLHATKKTYNLKASPARKPQARLSPVKGKTIRMRSDELFSRQDTVPVHRRLGKTATSAPLRAPPAPPHRQPRPEPQKKYVPPRRHNSMNAGHSRQRDQSGSVFDRLGFNNSM
Protein: serine-rich chaperone protein 1 (HssA/B-like protein 63) (Q54BX3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Chaperone that suppresses aggregation of proteins with long polyglutamine (polyQ) tracts. Acts by promoting degradation of polyQ aggregates by the proteasome.
Interaction partners:
Sequence:
MTILSTFTSFSNPPKLNKSSFSSSTGSSLSMGSNSFAWGGGWGGFGGPKGGSFNVDIAGNLIWGVYGFIRGGVGLVKWRGLQKGCKQP
Protein: Protein-arginine N-acetylglucosaminyltransferase NleB1 (Arginine GlcNAcyltransferase NleB1) (EC 2.4.1.-) (Non-LEE-encoded type III effector B1) (B7UI21)
Organism: Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Function: Protein-arginine N-acetylglucosaminyltransferase effector that disrupts TNF signaling in infected cells, including NF-kappa-B signaling, apoptosis and necroptosis. Acts by catalyzing the transfer of a single N-acetylglucosamine (GlcNAc) to a conserved arginine residue in the death domain of host proteins FADD, TRADD, FAS, TNFRSF1A/TNFR1, TNFRSF25/DR3 and RIPK1: arginine GlcNAcylation prevents homotypic/heterotypic death domain interactions and assembly of the oligomeric TNF-alpha receptor complex, thereby disrupting TNF signaling. Has preference for host FADD as substrate compared to other death domain-containing proteins. Also acts on host proteins without a death domain: catalyzes arginine GlcNAcylation of HIF1A, thereby regulating host glucose metabolism. Also displays intra-bacterial activity by mediating GlcNAcylation of glutathione synthetase GshB. Catalyzes auto-GlcNAcylation, which is required for activity toward death domain-containing host target proteins. Shows a higher enzymatic activity than NleB2.
Subcellular location: Secreted {ECO:0000250|UniProtKB:A0A482PDI9}. Host cytoplasm {ECO:0000269|PubMed:32432056}. Note=Secreted via the type III secretion system (T3SS). {ECO:0000250|UniProtKB:A0A482PDI9}.
Interaction partners:
Sequence:
MLSSLNVLQSSFRGKTALSNSTLLQKVSFAGKEYSLEPIDERTPILFQWFEARPERYEKGEVPILNTKEHPYLSNIINAAKIENERIIGVLVDGNFTYEQKKEFLNLENEHQNIKIIYRADVDFSMYDKKLSDIYLENIHKQESYPASERDNYLLGLLREELKNIPEGKDSLIESYAEKREHTWFDFFRNLAILKAGSLFTETGKTGCHNISPCSGCIYLDADMIITDKLGVLYAPDGIAVHVDCNDEIKSLENGAIVVNRSNHPALLAGLDIMKSKVDAHPYYDGLGKGIKRHFNYSSLHNYNAFCDFIEFKHENIIPNTSMYTSSSW
Protein: Ceramide kinase-like protein (Q49MI3)
Organism: Homo sapiens (Human)
Function: Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis in oxidative stress conditions.
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Enriched in nucleoli. May shuttle between nucleus and cytoplasm. Isoform 5 is not enriched in the nucleoli.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus, nucleolus. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum.
Interaction partners:
- Protein eyes shut homolog
- Tubby-related protein 1
- Retinol dehydrogenase 12
- Cyclic nucleotide-gated channel beta-1
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
- Retinal-specific phospholipid-transporting ATPase ABCA4
- Photoreceptor cilium actin regulator
- Cyclic nucleotide-gated channel alpha-1
- Photoreceptor disk component PRCD
- U4/U6 small nuclear ribonucleoprotein Prp31
Sequence:
MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGITLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMIPK
Protein: Putative protein N-methyltransferase FAM86B2 (EC 2.1.1.-) (P0C5J1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAPEENAGTELLLQGFERRFLAVRTLRSFPWQSLEAKLRDSSDSELLRDILQKTVRHPVCVKHPPSVKYAWCFLSELIKKHEAVHTEPLDKLYEVLAETLMAKESTQGHRSYLLSSGGSVTLSKSTAIISHGTTGLVTWDAALYLAEWAIENPAAFINRTVLELGSGAGLTGLAICKMCRPRAYIFSDPHSRILEQLRGNVLLNGLSLEADITGNLDSPRVTVAQLDWDVAMVHQLSAFQPDVVIAADVLYCPEAIVSLVGVLQRLAACREHKRAPEVYVAFTVRNPETCQLFTTELGRDGIRWEAEAHHDQKLFPYGEHLEMAMLNLTL
Protein: Probable plastid-lipid-associated protein 5, chloroplastic (Fibrillin-3b) (Q6DBN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast thylakoid {ECO:0000269|PubMed:22274653}. Note=Located in thylakoid as a peripheral protein at the stromal side. {ECO:0000269|PubMed:22274653}.
Interaction partners:
Sequence:
MALPWCLKTGVLTSPAAGFNHPSDSGFAVPTKLLSIRKGDRERLRIQAVFSFPPRNGGAEKRKQLKHELVEAIEPLERGATASPDDQLLIDQLARKVEAVNPTKEPLKSDLINGKWELIYTTSAAILQAKKPRFLRSLTNYQCINMDTLKVQRMETWPFYNSVTGDLTPLNSKTVAVKLQVFKILGFIPVKAPDGTARGELEITYVDEELRISRGKGNLLFILKMFDPTYRIPL
Protein: Tryptophan 2-monooxygenase oxidoreductase protein (EC 1.13.12.3) (Q8XUN6)
Organism: Ralstonia nicotianae (strain ATCC BAA-1114 / GMI1000) (Ralstonia solanacearum)
Interaction partners:
- Histidinol-phosphate aminotransferase 2
- Phenylalanine-4-hydroxylase
- Histidinol-phosphate aminotransferase 1
- Aminotransferase
- Aminotransferase
- Aminotransferase
- Catalase-peroxidase
- Aminotransferase
- Cyclohexadienyl dehydratase signal peptide protein
- Bifunctional chorismate mutase/prephenate dehydratase
Sequence:
MGITVMPGLTSMESDTRTQRISTTIGQARLNGRFYRHPDSALVSYPVAVDNALGALPDRAYNIAIVGGGAAGIASLYELSRLAKTLSAGTMTVTLYESDPDSFLTRLEAGTQAINVRGLKAGRVSAARVNQNDTVYEVGAMRFPEIAGLTWHYASVVYGDGAPIKVFPNPGKVPTEFMFGDRIDRYSGSAPEDWLDRESPARKVFLVVASGLAGAPDSQTPIALFPIGGRDPVQVAQLLKSETAGPAQLRAIQERDWPAFIAAHDGTTLEAAVRRIVTREIGKGAASSLPPIAGLDPAETINYYVELFGRFGFGTGGFKPLFNISLVEMMRLILWDYSNEYTLPVEENVEFIAGLYQKALEQGGSRLTVNVRRERVSDVCHSDAARVRQPFVVAYDRAGKLSAPNYDYVILAAPQDQLALAVSRSGYAFGPASLVLGDGALGLGTITIRDALPPLLLSDTSSAPNARIVTALNQLHMVRSSKVFGTIETARLDEPFVPRLKGQPIKAVVSDSGLAASYVVPSPTEPGAPRYSSFLASYTWGDDSTRLQHNFGYYPQNPPTSDGTATAMFRTMINRATRNVRDPAEPAAAPAVWWFSQLLSRVREQDRFVFDWTTNGTAGGFKLDGTGDHHQSNLCFRYHTHALNPRLGNRFFLASDSYSHLGGWLEGAFMSAINAVAGLVVAANGGNAGALSNAAREVVTGLRPIAP
Protein: Caveolin-2 (P51636)
Organism: Homo sapiens (Human)
Function: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
Subcellular location: Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments. {ECO:0000250}.
Interaction partners:
- Caveolin-1
- Caveolin-3
- Epidermal growth factor receptor
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase Fyn
- Calmodulin-like protein 3
- Calmodulin-like protein 5
- Major prion protein
- Calmodulin-like protein 4
- Calmodulin-like protein 6
Sequence:
MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
Protein: Uncharacterized protein (Q2U3V9)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- fumarate hydratase
- Succinate--CoA ligase subunit alpha, mitochondrial
- CoA-binding domain-containing protein
- Succinate--CoA ligase subunit beta, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- 4Fe-4S ferredoxin-type domain-containing protein
- Uncharacterized protein
- NADH-quinone oxidoreductase subunit D domain-containing protein
Sequence:
MISQKVAQQSLRRLAVQQPYAMRWSLMNSATPAAVAMGRFMQTRQAATTSNTSDPTKILAQQRLNRPVSPHLSIYRPQITWIGSSFHRITGFALSGSLYLYATAYLASPLLGWHLESASVAAAFAALPIVAKVLLKGFMALPFTYHCFNGVRHLVWDLGRGITNQQVIKSGWTVVGLSVLSALALAFL
Protein: EUL55 (Nuclear protein) (ORF 4) (ORF4) (UL4) (Q2END6)
Organism: Equid alphaherpesvirus 1 (Equine herpesvirus 1)
Subcellular location: Host nucleus matrix {ECO:0000256|ARBA:ARBA00004428}. Virion tegument {ECO:0000256|ARBA:ARBA00004535}.
Interaction partners:
Sequence:
MLPANRAEHSSDAEPRDIGSHGRNHGGCYSSDCKLGLLVDISNVVSPLPLDLTWSSWETTSQPARSRSYLNTRTYTIRACCDLQTRLHAFFIGVFEKRDPEKQILLPDLTNFKCILNNPRIMQELATEHSVCSAPFSAATQYDCDEDGEESTINGLCFHCHCKTPFSLECWQAANSAQAKILSVARGITSAKERQRENKR
Protein: Formin-like protein 9 (AtFH9) (Q8GX37)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Might be involved in the organization and polarity of the actin cytoskeleton.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Formin-like protein 12
Sequence:
MQNFWFAIFFFLLTCAPPSPLSYASTVTLSRRLLYDYESPLPLPLSPISPPFFPLESSPPSPPPPLPPTPPTTFAVFPTFPANISALVLPRSSKPHHTSPTLLLPALSAVLVIATVIGLALFLYGRHRGQTRHLKNSHCSSSNTSSYGDEQSHITTNFNMAATTSPSEVFYLNTEESDHIRTGGTFFLKQDSPEIRPLPPLPPRSFHHNNYETEVNEEDEEEEEDVFFSPMASLPGSANSSPSHSCSSSCSGWVSPARSFSITMSPPNPRYSDATNLQSPSPERLRVRKNYNGNGSSSLRMFSFWNQNMGFGFPRISSASTSPDRGFIRTPLSSLYSSVSTSPDGLFRKFLDSSPPIWNDFSRNVKSVLLSHTASSRRDFVINIGESSSQQSKVPALPPPTRPPPLVPPSQPFVVQNDVKKQSFSDQPPKQLHWERLRSSSSKLSKEMVETMFIANSSNPRDLPIQNQVLDPRKAQNIATLLQLLNLSTKDVCQALLDGDCDVLGAELLECLSRLAPSKEEERKLKSFSDGSEIGPAERFLKELLHVPFVFKRVDALLFVANFHSEIKRLRKSFSVVQVACEELRNSRMFSILLEAILKTGNMMSVRTNRCGDADAFKLDTLLKLVDVKGLDGRSSLLHFVVQEMMKSEGSVRALEGIRNLNTELSNVKKSADIEYGVLRSNVSRICQGLKNIEALLLLSEESGSYGDQWLKFKERMTRFLKTAAEEIVKIKIRESSTLSALEEVTEQFHGDASKEGHTMRIFMIVRDFLSVLDQVCKEMGD
Protein: At3g51010 (Protein translocase subunit) (Q9SD44)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Putative B3 domain-containing protein At1g05615
- Cysteine/Histidine-rich C1 domain family protein
- Immune-associated nucleotide-binding protein 9
- Large ribosomal subunit protein eL20z
- At1g01640
- Small ribosomal subunit protein uS13m
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein mL53
Sequence:
MGFGAIRSILRPLSRTLVSRAVVNYSSAPFNATIPAAKPELCSFFGGSMTHLRLPWIPMANHFHSLSLTDTRLPKRRPMTHPKRKRSKLKPPGPYAYVQYTPGQPISSNNPNEGSVKRRNAKKRIGQRRAFILSEKKKRQALVQEAKRKKRIKQVERKMAAVARDRAWAERLIELQQLEEEKKKSMSS
Protein: cGMP-specific 3',5'-cGMP phosphodiesterase 3 (EC 3.1.4.35) (Phosphodiesterase 3) (DdPDE3) (B0G0Y8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Phosphodiesterase specific for cGMP, which is not activated by cGMP. Involved in the degradation of intracellular cGMP.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:12429832, ECO:0000269|PubMed:17040207}.
Interaction partners:
- 3',5'-cyclic-AMP phosphodiesterase 4
- cGMP-dependent 3',5'-cGMP phosphodiesterase A
- cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase A
- cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B
- cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase 7
Sequence:
MAPQQNIMKQLQQMQSSPYPSSSPSSTTVSQNNDNLNHNVHSLNNSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSINEKNKINDNNNRGNSDDGNNNNSNNNSNNNNSNNNNRDDEEEEGDDEDNNNNNNSNNNKIRGYNDNNDINDIFSINFSSWSKSKDNLIENGVLIFEESGLYKELNLSKSSILNFLSIVASSYRNNPFHSFNHAIAVTQTIFLILLKTNLFNILSPIEKLSIIIASICHDLDHPALSNRFQINMKSSIAVLYNNKSVLENHHLSICLGILESKIGNELLSTLTVEEKKQFFRRVKILILATDMENHFTYKKQFDDIISTFSWDNSEHRDLLLIMFLKSADISNELRSFDISNKWANALMEEFFNQSDLEKLNNLPLTPFMEREKVVLHLTQVSFIEKFLLPSYQSLQNLLPSLEDFVQRIIENKEIWSNNGSSSSTTSSSPN
Protein: SNF4/AMP-activated protein kinase gamma subunit (O96613)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNSMKVAMQNFSHRQHPAVTITSADGTQSTAKSKYKDGSAHPHQGSDAQYYHTVTAVRPNSSQRSPMTKVMDLFRHRSSSVVSEADKRKARAAAHQQQLAVQSAHMRRASADLEKRRASVGAAGRGLRGDGTLDPHHAAILFRDSRGLPVADPFLEKVNLSDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYALVYNGVRAAPLWDSEKQQFVGMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWRDVLHNQVMPLVSIGPDASLYDAIKILIHSRIHRLPVIDPATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRELKIGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDVSLRKANEHRNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPSGEGVGGSESSLRASDPVLLRKVAEVEIPATAAAATTTTPPRSPSAGSGNRSLIEDIPEEETAPARSDDADSDNNKSASEDKANNNQHDQTTTAATANGDSNNSPVEVSFADEAQEEEAADQVERSNCDDDDQPALAEIERKNASMDDDEDDGMSSAVSAASALGQSLTPAAQEMALVSE
Protein: Noelin-2a isoform X1 (Olfactomedin 2a) (F1R5K6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MSVPLLKIGAVLSTMAMVTNWMSQTLPSLVGLNGTTISRAGTSERIVSALYPSPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLMEKVQNITQSMEVLDLRTYRDLQYVRDTENLMKTVDGKLKTASENPRSLNPKSFQELKDKVTQLLPLLPVLEQYKADARMILRLREEVRNLSLVLMAIQEEMGAYDYEELRQRVLLLETRLHSCMQKLGCGKLTGVSNPITVRASGSRFGSWMTDTMIPSSDNRVWSMDGYFKGRRVLEYRTMNDFMKGQNFVQHLLPHPWAGTGHVVYNGSLYYNKYQSNILIKYHFRSRSVLVQRSLSGAGYNNTFPYSWGGSSDIDLMADENGLWAVYTTIPNAGNIVISRLEPQSLEVLQTWDTGFPKRSAGESFMICGTLYVTNSHLAGAKIYFAYYTNTSTYEYTDIPFHNQYSHISMMDYNPRERVLYTWNNGHQVLYNVTLFQVIKTAED