wanglab/gogpt-training-data huggingface dataset:
Protein: Transcriptional regulatory protein ASH1 (Daughter cells HO repressor protein) (P34233)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5'-YTGAT-3' sites. Also involved in pseudohyphal growth.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:8625408, ECO:0000269|PubMed:8625409, ECO:0000269|PubMed:9566907, ECO:0000269|PubMed:9809065}. Note=Preferentially accumulates in daughter cell nuclei at the end of anaphase.
Interaction partners:
- SWI5-dependent HO expression protein 2
- SWI5-dependent HO expression protein 3
- Histone deacetylase RPD3
- Transcriptional regulatory protein RXT2
- Transcriptional regulatory protein SIN3
- Transcriptional regulatory protein PHO23
- Transcriptional regulatory protein UME1
- Transcriptional regulatory protein SDS3
- Transcriptional regulatory protein DEP1
- Myosin-4
Sequence:
MSSLYIKTPLHALSAGPDSHANSSYYDNLLLPSFSNLSSNISRNNITTDNNINSASPRKYSFHSLNVSPILSPISLANEILGKKSNTAPASPHHMDYNPISSLTPGNSPEFNKASLSQISFTNPLNYGSGLGFSSNSQPRLPLLDRLSSVSLSKRPERPQQSLPSLRHLQLLPSPLLQENAARFPDTSKRTSNWKTDLTHWCKDTNYQDYVKIREEVAHFKPLSIPNLTNNQNNDSFNYGKELESTRSSKFHSPSKESFDRTKLIPSILEAKDQFKDLSNNAWSITPPVTPPMSPPTNRTMERTTLRGVEASFFEGKSSNNDSIFNPIISEKLVQEVKHQRQLRGNSFPMPNASHKKTNSFKALQIKKLLANRDILSNNSKSNVRKPSKNKISKQASNVFGNTARQLVMKLDNASYSSVSASSSPSPSTPTKSGKMRSRSSSPVRPKAYTPSPRSPNYHRFALDSPPQSPRRSSNSSITKKGSRRSSGSSPTRHTTRVCVSCHSSDSPCWRPSWSPRKQDQLCNSCGLRYKKTHTRCLNDLCRKIPTKGEINIMKSNGIDKEFVPERNCEIEGYRCLFCNYITETVEN
Protein: Ferrochelatase (EC 4.98.1.1) (D3ZBM3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000607}.
Interaction partners:
- Amine oxidase
- Uroporphyrinogen decarboxylase
- ATP-binding cassette sub-family B member 10, mitochondrial
- Heme oxygenase 2
- Heme oxygenase 1
- Protoheme IX farnesyltransferase, mitochondrial
- Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
- Ceruloplasmin
- Hephaestin
- Porphobilinogen deaminase
Sequence:
MLSAGANMAAALRAAGALFREPLVYGSSRACQPWRCQSGPAVVATTEKAHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPDTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVHRVMEQLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHIQSNKLCSTQLSLSCPLCVNPVCRKTKSFFTSQQL
Protein: SbsB protein (Q45664)
Organism: Geobacillus stearothermophilus (Bacillus stearothermophilus)
Interaction partners:
Sequence:
MAYQPKSYRKFVATTATAAMVASAVAPVVSAASFTDVAPQYKDAIDFLVSTGATKGKTETKFGVYDEITRLDAAVILARVLKLDVDNAKDAGFTDVPKDRAKYVNALVEAGVLNGKAPGKFGAYDPLTRVEMAKIIANRYKLKADDVKLPFTDVNDTWAPYVKALYKYEVTKGKTPTSFGAYQNITRGDFAQFVYRAVNINAVPEIVEVTAVNSTTVKVTFNTQIADVDFTNFAIDNGLTVTKATLSRDKKSVEVVVNKPFTRNQEYTITATGIKNLKGETAKELTGKFVWSVQDAVTVALNNSSLKVGEESGLTVKDQDGKDVVGAKVELTSSNTNIVVVSSGEVSVSAAKVTAVKPGTADVTAKVTLPDGVVLTNTFKVTVTEVPVQVQNQGFTLVDNLSNAPQNTVAFNKAEKVTSMFAGETKTVAMYDTKNGDPETKPVDFKDATVRSLNPIIATAAINGSELLVTANAGQSGKASFEVTFKDNTKRTFTVDVKKDPVLQDIKVDATSVKLSDEAVGGGEVEGVNQKTIKVSAVDQYGKEIKFGTKGKVTVTTNTEGLVIKNVNSDNTIDFDSGNSATDQFVVVATKDKIVNGKVEVKYFKNASDTTPTSTKTITVNVVNVKADATPVGLDIVAPSEIDVNAPNTASTADVDFINFESVEIYTLDSNGNRLKKVTPTATTLVGTNDYVEVNGNVLQFKGNDELTLLTSSSTVNVDVTADGITKRIPVKYINSASVPASATVATSPVTVKLNSSDNDLTFEELIFGVIDPTQLVKDEDINEFIAVSKAAKNDGYLYNKPLVTVKDASGKVIPTGANVYGLNHDATNGNIWFDEEQAGLAKKFSDVHFDVDFSLANVVKTGSGTVSSSPSLSDAIQLTNSGDAVSFTLVIKSIYVKGADKDDNNLLAAPVSVNVTVTK
Protein: Adhesion G protein-coupled receptor B2 (Brain-specific angiogenesis inhibitor 2) (Q8CGM1)
Organism: Mus musculus (Mouse)
Function: Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O60241}; Multi-pass membrane protein {ECO:0000255}. Secreted {ECO:0000250|UniProtKB:O60241}.
Interaction partners:
- E3 SUMO-protein ligase RanBP2
Sequence:
MTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCTHFAPRLLPLDHYLVNFTCLRPGPEEATARAESEVGRPEEEEEEAAAAASGLELCGGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGANPATTTSPGPPVAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGPCSSSCANGTQQRSRKCSVAGPAWATCAGALTDTRECSNLDCPATDGKWGPWNAWSLCSKTCDTGWQRRFRMCQASGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKRAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSADDVQRFFQVVSFMVDSENKDKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPISAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATPGAATAGSPGRGRGPGTVPPGPGHAHQRLLPADPEESSSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADTNSGDWNTESCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGAPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGVSDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGGLSFSPLPGNILVPMAASPGLGEPPPPQETNPVYMCGEGGLRQLDLTWIRQSEPGSEGDYMVLPRRTLSLQPGGGGTAGEEAPRARPEGTPRRAAKTVAHTEGYPSFLSVEHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGERSRTMPRTVPGSTMKLGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQSSAKEKPSPPGGRPGLSQHRRHQSWSTFKSMTLGSLPPKPRERLALHRTAAWEPTEPPDGDFQTEV
Protein: Odorant receptor coreceptor (E2BJ30)
Organism: Harpegnathos saltator (Jerdon's jumping ant)
Function: Odorant coreceptor which complexes with conventional odorant receptors (ORs) to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity). Obligate coreceptor of all odorant receptors (By similarity). Orco is a universal and integral part of the functional odorant receptor, involved in the dendritic localization of other olfactory receptors. Can form functional ion channels in the absence of an odor-binding odorant receptor (By similarity). Plays a central role in the perception of olfactory stimuli in ants and is essential for ant social organization. Required for pheromone sensing and mating behavior. Also required for the development and maintenance of odorant receptor neurons (ORNs) and of antennal lobe glomeruli.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MMKMKQQGLVADLLPNIRVMKFFGHFVFNYYDDNSSKYLHKIFCCVNLFLLLLQFALCAVNLIIESADVDDLTANTITLLFFTHSIVKIIYFAVRSKYFYRTWAIWNNPNSHPLFAESNARYHAIALKKMRLLLFLVGATTVLSAIAWTVLTFFEHPIRKLVDPVTNETTIIELPQLLLRSYYPFDASKGIMHVIVLIYQFYWVLFMLIDANSLDVLFCSWLLFACEQLQHLKQIMKPLMELSATLDTVVPNSSELFKAGSAEHLRESENQPPPPVPPQGDSMLDLDLRNIYSNRQDFTATFRPTAGMTFNGGVGPNGLTKKQEMLVRSAIKYWVERHKHIVRLVTAVGDAYGFALLLHMLTTTITLTLLAYQATKVNGVNVYAASTIGYIIYTFGQVFLFCIFGNRLIEESTSVMEAAYSCHWYDGSEEAKTFVQIVCQQCQKAMSISGAKFFTVSLDLFASVLGAVVTYFMVLVQLK
Protein: FXYD domain-containing ion transport regulator (Q58K79)
Organism: Sus scrofa (Pig)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004183}; Single-pass type III membrane protein {ECO:0000256|ARBA:ARBA00004183}.
Interaction partners:
Sequence:
MAGLSTDDGGSPKGDVDPFYYDYETVRNGGLIFAALAFIVGLIIILSKRLRCGGKKHRPINEDEL
Protein: Protein SLX4IP (SLX4-interacting protein) (Q5VYV7)
Organism: Homo sapiens (Human)
Interaction partners:
- Structure-specific endonuclease subunit SLX4
- Structure-specific endonuclease subunit MUS81
- Structure-specific endonuclease subunit SLX1
- Telomeric repeat-binding factor 2-interacting protein 1
- DNA excision repair protein ERCC-1
- Structure-specific endonuclease subunit EME1
- DNA repair endonuclease XPF
- Telomeric repeat-binding factor 2
- DNA mismatch repair protein Msh3
Sequence:
MASKKFAVKCGNFAVLVDLHILPQGSNKDTSWFSEQKKEEVCLLLKETIDSRVQEYLEVRKQHRPSNAEFTRSNPLSLKGYGFQITAYFLKRGIRLRCIRSTQNAELCVFPDRFVVCVSQLAFSRDLLASQNEDLTERVLHGVSDYFAECAESSLPPSAKLRRNALKEIVKRTETKSSVTSKSQTRRDTVETSSDSVIAEIARRRNDGQASSSPPSESMGQAKDSIKAAESHWGLPVQKLEKVNQTQPEDTSGQQKPHPGERLKTGLLSRSPVCSCESASPCPKQSPRVAKTQQKRRNCSSAEDFDHHGRVSLGSDRLVPREIIVEKSKAVRVLPASELSDPGLLLKQDLAKTTSKEELHVLESLSSRHLMKNNPGQAQQTGLATNTERLSTIQNSPTKKRKKYERGH
Protein: Type II secretion system protein F (T2SS protein F) (General secretion pathway protein F) (Q00513)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Type II secretion system protein E
- Type II secretion system protein L
- Type II secretion system core protein G
- Type II secretion system protein M
- Type II secretion system protein I
- Secretin XcpQ
- Type II secretion system protein H
- Prepilin leader peptidase/N-methyltransferase
- Type II secretion system protein J
- Type II secretion system protein K
Sequence:
MAAFEYLALDPSGRQQKGVLEADSARQVRQLLRERQLAPLDVKPTRTREQSGQGGRLTFARGLSARDLALVTRQLATLVQAALPIEEALRAAAAQSTSQRIQSMLLAVRAKVLEGHSLAGSLREFPTAFPELYRATVAAGEHAGHLGPVLEQLADYTEQRQQSRQKIQLALLYPVILMVASLAIVGFLLGYVVPDVVRVFIDSGQTLPLLTRVLIGVSDWVKAWGALAFVAAIGGVIGFRYALRKDAFRERWHGFLLRVPLVGRLVRSTDTARFASTLAILTRSGVPLVEALAIAAEVIANRIIRNEVVKAAQKVREGASLTRSLEATGQFPPMMLHMIASGERSGELDQMLARTARNQENDLAAQIGLMVGLFEPFMLIFMGAVVLVIVLAILLPILSLNQLVG
Protein: Phosphatidylinositol-4-phosphate 5-kinase related (Q4GZE4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFVRRLVRLCVSRLPNGVVLQGKLNPRRPDLLLEGSVKMPDGRAYSGVFDEEYGFPLKGSRLEDDGDLYCGEFNTKWQRHGEGEAWLADGTHYKGRFCEDDLVEGTVCIPNGTTETVFVGTLENESFVRGKLTQHDFTYEGEFHNNKPHGRGRLSFTTGAEQEGTFFAGKLHGTNCKMKLDGGFVYVGEFVDGCIRRGQLFAPTYIYDGEFNEHGRAHGEGTQTYLANEPRLLFTGIWDSGALVRGTCSDEYGNPVDWQDNHELQTKVFSEEGGASAVAMNCYSAAKLKDADRLHRDMNTSYAKDAERVSRNSGHYPSKMDLGYEGGIRQEQDAFERASRKCVEDTRRAREAMETKGEDINRLCDNVIGEASIEVNPNMAKMHFIKQEGAQQLAAEHVDEQFERFMKSFDRPTDVGASRRLIDCNAPWKAFTSKG
Protein: TIMEOUT (Q9NG27)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSILLADIDATCAALGYSDGQKYQAEPDAAEGLKHLIWILRRDLDNHEYRRHLGRSKVLQTDLVYMLPDYVHHEELSDLLIRLLVILTNPTLLLYREGAPKDNHGRKVFMELIDILQGYKAAFAKDKVWSALFEKLKQALEIAFAIRSEEQNLLIERILVLVRNVLQVPANPEAECRADNDASLHDQVIWALHQTGMLDLVLFVISSPDEEQFHLHGLEIVCLLFREQSAESLADASLQRSLSEKQRDQQELLAARRRERARRQARPPPGRHSRFGGTYVIRNMKSVSDRDVICHQALERVSSIDFDREKQQQKRSHRHIQEEAQVTRRSAFTVRLCLREYCIEVLRSAYNTLVRQVRRVLERNAGSSSHDDSYLLWAIRFFMEFNRLSGLQLQLVSESLSVQCFHWVLTRMQHDMDMIVSDKKQARLWAKRLHVALKTFRELLQSLLALQKLKDDNNARALFDMLLNNVCYVLEYRETVLHLLMNYNEAHSTKVFLRDVVETANVFIKMMERFCQDSVVVQDKKRGRGASRKKKQAATKSKPPAAPQPTEEELSSKWAELATEVCSLLSTELEMPEDEQPLPFDAASEKSIDDQREDCMIRINKLLRSEKLDQAIALLRAAREVWPENEVFGAISAAPEDELLLLREIFMSNITTVESEDKENEKDQKQDEYEDEDDDLDNEEYEEQDNGLTEKTFKFDDFARRLLNPKIVRACTLVLSDWADIPTRSLKAAVTILHRIAYGCKCAGMLFQAKLFRIFQQVFSVERDVHQEELRRLAIFVVRKFVEVAPTNPKIYAELLFYKGIREANELESGYCDAYEAGTKGAWTEEQESELRFLFEENQRNPETDKDVIDWILDNLVDKTRNRRTVLKKLKELGLLFKAPTKRSTKSAQSGKNVWQPEEDDELRSLYDQHRIEPDCLERLVNEFAERRSKQQIIKRMLQIHLIADKSEILPAKKGRGKDKPKKDVEMEGEGDEFDFAEEPMFEDQGYKKPKSKPKKVQKRQMVRTPLDVGTIRALIGQVDSEKYQSAIEWLQECLQDASEDTEEAVEDDDGVPLLPLMENQKNAMEDGDFQKVLVALGMQPPISGMEAYWRIPIYLNSADLILRSKILAGEEVDAEPEDEAADDEDGEEAEESDEEEDFLEKHSRQRKENIATQQQRKLDSLMFNQSDDETEQRAPPKAKDKPKASEKKAKRKVKGKAKESKDCNDDGTDKAELEKPNTDDLFNQLRAKRATKIKLSDMALNESTNAAQEADDDAFNFNSEDYRARLLELEDEEQNSKDADENGGDKENITNKSLQRARRVNVIDSDSDNDDDGALPADKTNKRPRSDDDGDSGHMDANAEEDSDEEANFLARKKPAKVDGEPAKRRRLAIIDDDDEDDF
Protein: Endonuclease/exonuclease/phosphatase domain-containing protein (Q38FG5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLRISTPRLDGPMVTGGPVKGLQGRMRSLIKPSVAEHVLRDVAVVRQRFAELTDAGVEDPASTYKPSIPRPWVKAPLSRLSTSVSRRDWFRIMQFNIMADAWSNGGTTVERTTPVHGVLPWVPGFTRRGTDPCGFYPYDHSVDEEVPPFLQEDIRRAYIVNEICYYDPDIVCLQEVNRSFFNETFSKYIRYRGYGTLYQSSRGYKVRALRRGDDPTLLRHKGKIEEREDIGNVILFHKGRFVPILMPGKDLVQHLHFAHIVAMRDRVTNMTLNVACAQFTAGDSAEASEIRLHEARQTMQILDALNRNDTDRSHMSNVICGDFNNVEDEEPCVQFMRERLFSTYDVVGGPRWTTWFHEDAQSNARYQKYYSCNRAGYFATNAAKRAEQEVAKFTWLRSGGLNGRRQDVSGGDSAPPGTRSATISSLDKVVGANEPNTAARTLERGGTCGDVLVEQKQALKADGIIRRTQDFVLYDPKTLALHQVLDVPEDEHIDSQQLLPCSGHPSHHLHLVVDVSFTDVCPDVGEISIKD
Protein: MAP3K epsilon protein kinase 2 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase 6) (Q9SFB6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine/threonine-protein kinase involved in the spatial and temporal control system organizing cortical activities in mitotic and postmitotic cells. Required for the normal functioning of the plasma membrane in developing pollen. Involved in the regulation of cell expansion and embryo development.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q8T2I8}. Nucleus, nucleolus {ECO:0000269|PubMed:15292395}. Cell membrane {ECO:0000250|UniProtKB:Q9LJD8}. Note=Accumulates in the nucleolus during interphase (PubMed:15292395). Localized to the plasma membrane in developing pollen grains (By similarity). {ECO:0000250|UniProtKB:Q9LJD8, ECO:0000269|PubMed:15292395}.
Interaction partners:
Sequence:
MARQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIGLDLENGDFVAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIVKYLGSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEADFNTHSVVGTPYWMAPEVIELSGVCAASDIWSVGCTIIELLTCVPPYYDLQPMPALYRIVQDDTPPIPDSLSPDITDFLRLCFKKDSRQRPDAKTLLSHPWIRNSRRALRSSLRHSGTIRYMKETDSSSEKDAEGSQEVVESVSAEKVEVTKTNSKSKLPVIGGASFRSEKDQSSPSDLGEEGTDSEDDINSDQGPTLSMHDKSSRQSGTCSISSDAKGTSQDVLENHEKYDRDEIPGNLETEASEGRRNTLATKLVGKEYSIQSSHSFSQKGEDGLRKAVKTPSSFGGNELTRFSDPPGDASLHDLFHPLDKVPEGKTNEASTSTPTANVNQGDSPVADGGKNDLATKLRARIAQKQMEGETGHSQDGGDLFRLMMGVLKDDVLNIDDLVFDEKVPPENLFPLQAVEFSRLVSSLRPDESEDAIVTSSLKLVAMFRQRPGQKAVFVTQNGFLPLMDLLDIPKSRVICAVLQLINEIVKDNTDFLENACLVGLIPLVMSFAGFERDRSREIRKEAAYFLQQLCQSSPLTLQMFISCRGIPVLVGFLEADYAKHREMVHLAIDGMWQVFKLKKSTSRNDFCRIAAKNGILLRLVNTLYSLSEATRLASISGDALILDGQTPRARSGQLDPNNPIFSQRETSPSVIDHPDGLKTRNGGGEEPSHALTSNSQSSDVHQPDALHPDGDRPRLSSVVADATEDVIQQHRISLSANRTSTDKLQKLAEGASNGFPVTQPDQVRPLLSLLEKEPPSRKISGQLDYVKHIAGIERHESRLPLLYASDEKKTNGDLEFIMAEFAEVSGRGKENGNLDTAPRYSSKTMTKKVMAIERVASTCGIASQTASGVLSGSGVLNARPGSTTSSGLLAHALSADVSMDYLEKVADLLLEFARAETTVKSYMCSQSLLSRLFQMFNRVEPPILLKILECTNHLSTDPNCLENLQRADAIKQLIPNLELKEGPLVYQIHHEVLSALFNLCKINKRRQEQAAENGIIPHLMLFVMSDSPLKQYALPLLCDMAHASRNSREQLRAHGGLDVYLSLLDDEYWSVIALDSIAVCLAQDVDQKVEQAFLKKDAIQKLVNFFQNCPERHFVHILEPFLKIITKSSSINKTLALNGLTPLLIARLDHQDAIARLNLLKLIKAVYEKHPKPKQLIVENDLPQKLQNLIEERRDGQRSGGQVLVKQMATSLLKALHINTIL
Protein: Uncharacterized protein (Q38C57)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- GST N-terminal domain-containing protein
- Small ribosomal subunit protein uS5
- 40S ribosomal protein S25
- 60S acidic ribosomal protein P0
- 40S ribosomal protein S26
- 40S ribosomal protein S23, putative
- Eukaryotic translation initiation factor 3 subunit I
- 40S ribosomal protein S33, putative
- 60S ribosomal protein L4
- 40S ribosomal protein S14
Sequence:
MGQWLCFRGGSTEGGKECDGDELSVYSEVGEKMSREERYSNADCPDSGSSLLPGVMWSEQPVEQARFEDFGGSSCGSVFPPHRKHRDYKLFGGLFDANVSLLSLCSCEDAGMPQHILLGGEGGGIVLLNYASGEVVRRWSEAHSGDVNKLTRPLETGMFASCSRDSTVKVWDTECNEALCTLRGHRANVTSITQLLNGTFLVSGSRDNSVRLWDIIEGQEVACCDVKQNIVHFVRWVPSLGCVAQGGEDLTVRLWDVRTSSDGMKAIDLSLGFTMACIDYHPICCELSPDEGSYTLLTGHNGFNGHGAYVVEWDLRMQDRVRTFKAHNGTVRSIRSCPLAKGMPNRHYMSAADDGTVAFFSTADVDGAVEVSVDPANIHKVSGASVKCIDTSSGGDIFASTSDGAVIVCCQTQRGSEAVASLYHYRYFGASPG
Protein: CAP, isoform C (RE10170p) (Q7JR75)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
Interaction partners:
Sequence:
MGQEHTQSTTGTAMFAPKFKARAPPGSGVWTPYGSSGDLNQSGATSATPPPPPPPSLPVWTPQPSPVLSGRKEFRPVRFESPTLPRRYTAQQQQKTTTTIPPWSSAENGEGGPPPTAPASLNSVNSNSDYAETDCSGHFGPVAPSASVSDKIRTFERSSSNSELQRPFVRRQLSDASRPAYRPNEVIYKVKHEYMSEPETGSDRPRKMAQLGRRQYDGIGPVTNDGMPIILRSEVKEPHQHEWYKRLYQTIHKQKNGDDFVIRYKCPRARPSYKSNGYVSEPEPNYDSDYSTVRYRTQNPHRVQSVSSAVNVRNLNQDEKLYGTMPNPIKSAQNSYKNQPGRIENYTTGHSSVSEKEKKEWWDEVMDIFNGNLEQSKLSPLYTEGNLSRALAKESGYTSDSNLVFRKKEVPVSSPLSPVEQKQAYKSLQAGGEPPLLGFRKPAPEKPRDLDPNAPPIPPQPPVKGLSSYDFPYSTDTVDGSDVNIHFKTPIRHEQRQNLSEEELAIRQAEHMQKLYHEERRRKYLQELQDMNSRRHTDNFTPSQKSPIALNRYDDFPTDVTLKSLVGPKTVARALFNFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPSKRPSEGQARAKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTSSEPLAYRALYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYVERA
Protein: CYtochrome P450 family (O02628)
Organism: Caenorhabditis elegans
Interaction partners:
- Fatty acid synthase
Sequence:
MFFVLFFSVLLGYLIVRQYQKVSRLPPGPISLPLIGNLPQIIYYLWSTGGIVSTLDLFRKRYGNIFTLWVGPIPHVSIADYETSHEVFVKNAGKYADKFHAPVMRDVRNDIGVLITNGDHWQEMRRFSLQAFRNMGVGKDIMETRIMEELDARCSDIDKLATNGVTITHASEFFDLTVGSIINSILVGKRFEEDTKHEFLKIKETMDASFETFSPFDMTAPVWFLKTFFKHRYDKIWSAQETAKNFAAAEAIKRVESIKSGKYVIDENNLQDYTDAFLLKIQKEGESKDFNIETLKTMIIDLWMTGQETTTTTLISGFNQLLLHPEVMIKAREEILKITENGSRHLSLTDRTSTPYVNAVIGEIQRHASILNVSFWKINKEFTYMGGHPVDAGALVTSQLSALHVNETVFKNPQEFNPERFIRDGKLLQKVIPFGVGKRNCLGESLAKAELYLIFGNLLLRYKFEQHGKLSTTELMPYSAGKRPFKLEMKFVKI
Protein: Protein three rows (P42286)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required specifically for chromosome disjunction during all mitoses; maternally provided protein is sufficient until mitosis 14 then zygotic protein is required. Involved in formation and/or maintenance of epithelial structures: bud extension during Malpighian tubule development, and foregut and hindgut morphogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12231632}. Note=Cytoplasmic during interphase and distributed throughout the cell during early mitosis.
Interaction partners:
- separase
Sequence:
MSTDIATQLKGSRSDVEKVRKTVEAKFRELSGDGLPLRYEVNVLRHICLALKDNLHQNSDLYCDIMGIMLPRVVPCEEKPSLWEAHLSSLRYIHHGLFHQRSIEACQKLYNLIRQQPCRLQEESDYKIYLDIHLTHFNGFHVLLQKQKLPLEATSQLCYALESLGDLFAAMTQRQISLCATLLVQLNESLFGKRSRSFFKSLSFLPSESLAKMFNALLMLLASSTSSNLANLFPECLSLTLALVQIDMFSPQSNQQMSLQLLRMSKELFRQESNLCYALQLMYYYIKLIFVREPTGDFKRTYIDLSSKFQHFFEHKVASHAKEQWLADFLVAIQLLQVLIHQSNSKLQSPFQIFWQQFDGESSPEIYTAHFQLLQTCASLAVNITRSPLGCSCSHEACKSVRRHCILAYGLCALDAYINWKPAAEQRANVSPHKPLLGVVKYSMDVAKTMKCLGPTSVEIIKLVRQLTYVADQVTCPEQMSVLLPLLEPLQKLRPLVADQDMSSLLRRLFKASSHCGDSNIACRIQASYLASITNPARLRSQVCLYYHNLGKKGTEIKRCVYEWHESTPLPFPLTPDQKKQLYDTDFFALLHYLRSPSTAHMESLIRCRTSDYHLVLLARQMRKDDSISKKCIEVHDKLRQQRSLSRMDNLCLGHASVGLLLDALEAQKTKVSTKEITENMFEELLLSKNLWQMNIQREQRLVNYASEAISAFSNFFDRADQEPLSANETSIDWEALIDDAIATANALSSMGYQSEEDDAWLLLLRMGRLLEDRFTYLRALNHFLSQNEVSSRLNLKLGEEVEVAEELLDDLWPQLKNGKFFKRQQTTVMLCFCHLASYYARMECYSHAQLLLLHVEQLREEFPERQGKSDIVLLTLQTVRFRIGYQQRKPTNCRLPTPLRQLDILLDNVRSFCNLSSLDGGSLQLLLSTLVRESTECSANRLSERLSFSNIALHLVLQSGLALRAIEVFLAWLWTNLQMESFDKAQSKLRLIEHCLGIKQLNPTSRPEKEAIKDVAISDLASNMHLLQLVEPIRKQQLLNMASPNLLKMRPHSPNPQLDLDRYITLDVAPANLRENSQLQCLYFVTGCLHARLRFLQRNSEQLEEFYGRAHNWMQEKPPMSSALYPMLHAQQLYHLNYLRFARKHVEAISTAQLGLKMRSRAVDINFEYNFLAQLKTAQLELKPVGQDKPQVKILRRALVFNHSPEDKKRTATGSVSAVKNTASKVKQSAKKAPRFRIYEELELRPPSATSCSSSGGSGTENTPPSDHVDLNACQAIEISDDDDSPLVSTKKTQPKSREKAKPKATSKACKVLTLDNSLEIVETPTITTSTRSTRARLRQPVETPKTATLSSKRTRRQVLEAQAPETESISTRTRHRH
Protein: Transcription factor ETV7 (ETS translocation variant 7) (ETS-related protein Tel2) (Tel-related Ets factor) (Transcription factor Tel-2) (Q9Y603)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.
Subcellular location: Nucleus.
Interaction partners:
- Transcription factor ETV6
- Basic leucine zipper transcriptional factor ATF-like 2
Sequence:
MQEGELAISPISPVAAMPPLGTHVQARCEAQINLLGEGGICKLPGRLRIQPALWSREDVLHWLRWAEQEYSLPCTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYIKTQRRALVCGPFFGGIFRLKTPTQHSPVPPEEVTGPSQMDTRRGHLLQPPDPGLTSNFGHLDDPGLARWTPGKEESLNLCHCAELGCRTQGVCSFPAMPQAPIDGRIADCRLLWDYVYQLLLDTRYEPYIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKMVQDKHSHLEPLESQEQDRIEFKDKRPEISP
Protein: Respiratory burst oxidase homolog protein B (EC 1.11.1.-) (EC 1.6.3.-) (NADPH oxidase RBOHB) (AtRBOHB) (Q9SBI0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Calcium-dependent NADPH oxidase that generates superoxide.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Calcium-dependent protein kinase 5
- Calcium-dependent protein kinase 6
- Calcium-dependent protein kinase 10
- Calcium-dependent protein kinase 1
- Calcineurin B-like protein 10
- Calcium-dependent protein kinase 11
- Calcium-dependent protein kinase 2
- Calcium-dependent protein kinase 3
- Calcium-dependent protein kinase 9
- Calcium-dependent protein kinase 21
Sequence:
MREEEMESSSEGETNKISRCKATGSDNPDEDYVEITLEVRDETINTMKAKATLRSVLSGRLKTMVKSLSFASRRLDRSKSFGAMFALRGLRFIAKNDAVGRGWDEVAMRFDKLAVEGKLPKSKFGHCIGMVESSEFVNELFEALVRRRGTTSSSITKTELFEFWEQITGNSFDDRLQIFFDMVDKNLDGRITGDEVKEIIALSASANKLSKIKENVDEYAALIMEELDRDNLGYIELHNLETLLLQVPSQSNNSPSSANKRALNKMLSQKLIPTKDRNPVKRFAMNISYFFLENWKRIWVLTLWISICITLFTWKFLQYKRKTVFEVMGYCVTVAKGSAETLKFNMALILLPVCRNTITWLRTKSKLIGSVVPFDDNINFHKVVAFGIAVGIGLHAISHLACDFPRLLHAKNVEFEPMKKFFGDERPENYGWFMKGTDGWTGVTMVVLMLVAYVLAQSWFRRNRANLPKSLKRLTGFNAFWYSHHLFVIVYVLLIVHGYFVYLSKEWYHKTTWMYLAVPVLLYAFERLIRAFRPGAKAVKVLKVAVYPGNVLSLYMSKPKGFKYTSGQYIYINCSDVSPLQWHPFSITSASGDDYLSVHIRTLGDWTSQLKSLYSKVCQLPSTSQSGLFIADIGQANNITRFPRLLIDGPYGAPAQDYRNYDVLLLVGLGIGATPLISIIRDVLNNIKNQNSIERGTNQHIKNYVATKRAYFYWVTREQGSLEWFSEVMNEVAEYDSEGMIELHNYCTSVYEEGDARSALITMLQSLHHAKSGIDIVSGTRVRTHFARPNWRSVFKHVAVNHVNQRVGVFYCGNTCIIGELKRLAQDFSRKTTTKFEFHKENF
Protein: Evasin P1095 (A0A0K8RCE3)
Organism: Ixodes ricinus (Common tick) (Acarus ricinus)
Function: Salivary chemokine-binding protein which binds to host chemokine CXCL8.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MELNAFTILQIAVFIAVGYHANTHSPVAGSEVQKLTSDPNDDIDVSYCGMNCTVVNGKSDECSENCKCLHEGDDPKGICVAITYFGDWGDPNDDPKINEATPQTQIFEKKRK
Protein: Zyxin (Q62523)
Organism: Mus musculus (Mouse)
Function: Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1 (By similarity). {ECO:0000250}.
Interaction partners:
- Vasodilator-stimulated phosphoprotein
- Talin-1
- Talin-2
- Vinculin
- Paxillin
- Alpha-actinin-4
- Alpha-actinin-1
- Actin, cytoplasmic 1
- Actin, cytoplasmic 2
- LIM and SH3 domain protein 1
Sequence:
MAAPRPPPAISVSVSAPAFYAPQKKFAPVVAPKPKVNPFRPGDSEPPVAAGAQRAQMGRVGEIPPPPPEDFPLPPPPLIGEGDDSEGALGGAFPPPPPPMIEEPFPPAPLEEDIFPSPPPPLEEEGGPEAPTQLPPQPREKVCSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFVPKPSTKPAPGGTAPLPPWKTPSSSQPPPQPQAKPQVQLHVQPQAKPHVQPQPVSSANTQPRGPLSQAPTPAPKFAPVAPKFTPVVSKFSPGAPSGPGPQPNQKMVPPDAPSSVSTGSPQPPSFTYAQQKEKPLVQEKQHPQPPPAQNQNQVRSPGGPGPLTLKEVEELEQLTQQLMQDMEHPQRQSVAVNESCGKCNQPLARAQPAVRALGQLFHITCFTCHQCQQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGQPITDRMLRATGKAYHPQCFTCVVCACPLEGTSFIVDQANQPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHSARAQT