wanglab/gogpt-training-data huggingface dataset:
Protein: Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein) (HURP) (Q15398)
Organism: Homo sapiens (Human)
Function: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
Interaction partners:
- Hyaluronan mediated motility receptor
- Centrosomal protein of 55 kDa
- Kinesin-like protein KIF11
- Abnormal spindle-like microcephaly-associated protein
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Maternal embryonic leucine zipper kinase
- Cell division cycle protein 20 homolog
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Lymphokine-activated killer T-cell-originated protein kinase
- Targeting protein for Xklp2
Sequence:
MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAKIKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEILAQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVIPKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQTTSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLSSERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILEEGETKISQSELFDNKSLTTECHLLDSPGLNCSNPFTQLERRHQEHARHISFGGNLITFSPLQPGEF
Protein: C2 domain-containing protein (Q965S5)
Organism: Caenorhabditis elegans
Interaction partners:
- MARVEL domain-containing protein
- ATP-grasp domain-containing protein
- Syntaxin-1A homolog
- Ras-related protein Rab-3
- Acetylcholine regulator unc-18
- Synaptobrevin-1
- Phorbol ester/diacylglycerol-binding protein unc-13
- Dynamin
- Putative stoned B-like protein
- Liprin-alpha
Sequence:
MSVSKKKDEDKEKKFLGRLQYKLDYDFDKNSLTVVIIQAEELPAMDLGGTSDPYVKLFLLPDKKKKLQTKVQRKSLNPVFNESFTFKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPLGKVDLAATLERTDLIESPPENRLGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSFDVTSEKMQRVHLHVTVSDYDRVGSNERIGQVIIGTCATGVALKQWNDMLATPRRSVAQWHTLVPFNDD
Protein: Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor) (Q8CHT1)
Organism: Mus musculus (Mouse)
Function: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension.
Subcellular location: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=Associated with membranes. Localizes to axonal growth cones (By similarity). {ECO:0000250}.
Interaction partners:
- Ephrin type-A receptor 4
- Ephrin type-A receptor 1
- Transforming protein RhoA
- Cell division control protein 42 homolog
- Ephrin type-B receptor 2
- Ephrin type-B receptor 1
- Ephrin type-A receptor 2
- Ephrin type-A receptor 3
- Ephrin type-B receptor 4
- Ephrin type-A receptor 8
Sequence:
METKNSEDWGKPQRKSESSSRKSNHGPAEMRPALPPENREAPETGEETQNEEPRRLIPIQRHSLFNRAVRHRHKARSTSERRASDQADLPKMGKSVNERSAFNLPQGRLSPWRTPAQRDTGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQVGEDAGEEEEEEEEGEEEELASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCKGLPFSSFLILPFQRITRLKLLVQNILKRVEERSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ
Protein: Crp/Fnr family transcription regulator protein (D8J1B0)
Organism: Herbaspirillum seropedicae (strain SmR1)
Interaction partners:
- Adenylate cyclase protein
- Coproporphyrinogen-III oxidase
Sequence:
MNQSCHSTPITTPANAAAPLTHCSSLTAAREAAASSALRSCTACGMHQLCLPMGLDESDMKRLDKIIGRRKVARDDFLYRIGDRFTALYAVRVGHFKTYQENLDGDRQITGFQMPGELLGMDAISTEQHQCDAVALQDSEVCEIPFARLEQLFGQIPHLLRHFHRIMSHEITSEQNVIMLLGNMRAEQRFAAFLVNLSSRYAARGYSSTRFQLRMTRQDVGNYLGLTIESISRLISKFRKQGLLAVEQRDVEVVDLAALKRLAAGVDACTATPTRSTS
Protein: Cycloartenol synthase (EC 5.4.99.8) (2,3-epoxysqualene--cycloartenol cyclase) (Oxidosqualene cyclase) (Q55D85)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Converts oxidosqualene to cycloartenol (in vitro).
Interaction partners:
- Probable lanosterol 14-alpha demethylase
- Squalene monooxygenase
- Squalene synthase
- Isopentenyl-diphosphate Delta-isomerase
- Probable farnesyl diphosphate synthase DDB_G0278823
- Probable farnesyl diphosphate synthase DDB_G0268742
- Conditioned medium factor receptor 1
- Farnesyl diphosphate synthase
- Probable cytochrome P450 524A1
- Putative methylsterol monooxygenase DDB_G0269788
Sequence:
MTTTNWSLKVDRGRQTWEYSQEKKEATDVDIHLLRLKEPGTHCPEGCDLNRAKTPQQAIKKAFQYFSKVQTEDGHWAGDYGGPMFLLPGLVITCYVTGYQLPESTQREIIRYLFNRQNPVDGGWGLHIEAHSDIFGTTLQYVSLRLLGVPADHPSVVKARTFLLQNGGATGIPSWGKFWLATLNAYDWNGLNPIPIEFWLLPYNLPIAPGRWWCHCRMVYLPMSYIYAKKTTGPLTDLVKDLRREIYCQEYEKINWSEQRNNISKLDMYYEHTSLLNVINGSLNAYEKVHSKWLRDKAIDYTFDHIRYEDEQTKYIDIGPVNKTVNMLCVWDREGKSPAFYKHADRLKDYLWLSFDGMKMQGYNGSQLWDTAFTIQAFMESGIANQFQDCMKLAGHYLDISQVPEDARDMKHYHRHYSKGAWPFSTVDHGWPISDCTAEGIKSALALRSLPFIEPISLDRIADGINVLLTLQNGDGGWASYENTRGPKWLEKFNPSEVFQNIMIDYSYVECSAACIQAMSAFRKHAPNHPRIKEINRSIARGVKFIKSIQRQDGSWLGSWGICFTYGTWFGIEGLVASGEPLTSPSIVKACKFLASKQRADGGWGESFKSNVTKEYVQHETSQVVNTGWALLSLMSAKYPDRECIERGIKFLIQRQYPNGDFPQESIIGVFNFNCMISYSNYKNIFPLWALSRYNQLYLKSKI
Protein: Probable UMP-CMP kinase 1 (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) (Q8VY84)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03172}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03172}.
Interaction partners:
- Uridine 5'-monophosphate synthase
- UMP kinase
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase 1
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase II, chloroplastic
- Ribonucleoside-diphosphate reductase small chain A
- Ribonucleoside-diphosphate reductase small chain C
- Ribonucleoside-diphosphate reductase large subunit
- Uracil phosphoribosyltransferase, chloroplastic
Sequence:
METPIDAPNKDEHECPRWKKSTVVFVLGGPGSGKGTQCANVVKHFSYTHFSAGDLLRAEIKSGSEFGAMIQSMIAEGRIVPSEITVKLLCKAMEESGNDKFLIDGFPRNEENRNVFENVARIEPAFVLFFDCPEEELERRIMSRNQGREDDNIETIKKRFKVFVESTLPIISYYESKGKLRKINAAKSSEEVFEAVRVLFASET
Protein: Signal transducer and activator of transcription (A7LH49)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
Sequence:
MAQWCQLQLLESKYQEQVDQLYDDSFPMDIRQYLSKWIESIDWENVAVQDSLATVRFHDLLAQLDDQHSRFALENNFLLQHNIRKIKRNLQDHFQEDPVHMAMIISRNLKEEQKILAAAKSIETDRENTQTSMVLEKQKLDNKVKDMKNKVQEADQNVKSLEYLQDEHDFKENTLKNREHEMNGLTQKQLEHEKLQIAEMCFKLKFKRGEVVGQLAEVLNIAEAVQSDLISEELAEWKKRQQISCIGGPPNACLDQLQNWFTAVAESLQQVRQLLKELQELEQKYTYDNDPIKQQKGFLEGRALSLFRNLLEHSLVVERQPCMPTHPQRPLVLKTQVQFTVKLRFLVKLQEFNYQLKVKALFDKDVTEKKGFRKFNILGTNTKVMNMEESNGSLAAEFRHLQLKEQKVAGNRTNEGPLIVTEELHCICFESELNQSGLELKLETISLPIVVISNVSQLPSGWASILWYNMLTSEPKNLKFFLSPPAASWGQLSEVLSWQFSSVTKRGLNEEQLGMLADKLLGQKAQRNPEGLVPWTKFCKSLSEKSFPFWLWIEAILDLIKRHLLSLWNDGCILGFVSKEREKALLTGKCPGTFLLRFSESSRDGAITFTWVEHDQYDKPVFHAVEPYTKKELSAVSLPDIIRTYKVMAAENIPENPLRLLYPDIPKDKSFGKYYAGASEASEPMDVESSSSTGYMKTELISVSEVHPSRLQDNMMPMSPDVFGELKRSVRQCPVLDWS
Protein: SUN domain-containing protein 5 (Sperm-associated antigen 4-like protein) (Q9DA32)
Organism: Mus musculus (Mouse)
Function: Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:21159740, ECO:0000269|PubMed:25775128, ECO:0000269|PubMed:28945193, ECO:0000269|PubMed:29298896}; Single-pass membrane protein {ECO:0000269|PubMed:21159740}. Golgi apparatus {ECO:0000269|PubMed:25775128}. Note=During spermiogenesis, traffics through the Golgi apparatus before reaching the round spermatid inner membrane of the nuclear envelope and later migrates to the coupling apparatus of the sperm during sperm head elongation and differentiation. In mature spermatozoa, is localized to the coupling apparatus of the sperm head and tail in the implementation fossa. {ECO:0000269|PubMed:21159740, ECO:0000269|PubMed:25775128, ECO:0000269|PubMed:28945193}.
Interaction partners:
- Nesprin-1
- Protein KASH5
- Nesprin-4
- Nesprin-3
- Nesprin-2
- Polyamine-modulated factor 1-binding protein 1
- Spermatogenesis-associated protein 6
- SUN domain-containing protein 3
- Sperm-associated antigen 4 protein
- SUN domain-containing protein 1
Sequence:
MPRTRNIGALCTLPEDTTHSGRPRRGVQRSYISRMAEPAPANMNDPLLLPLRMNTPGLSLVQILLGYMSWLTYLACFLRTQTQQVFLNTCRCKLFCQKVMEKMGLLVLCVFGFWMFSMHLPSKVEVWQDDSINGPLQSLRMYQEKVRHHTGEIQDLRGSMNQLIAKLQKMEAISDEQKMAQKIMKMIQGDYIEKPDFALKSIGASIDFEHTSATYNHDKARSYWNWIRLWNYAQPPDVILEPNVTPGNCWAFASDRGQVTIRLAQKVYLSNITLQHIPKTISLSGSPDTAPKDIVIYGLESLPREEVFLGAFQFQPENVIQMFQLQNLPPRSFAAVKVKISSNWGNPRFTCMYRVRVHGSVTPPKDSHLEPLS
Protein: Myocyte enhancer factor 2C (A0A0R4J2G5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLCAVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNMQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGDRTTTPSRYPQHTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPSPDERESPSVKRMRLSEGWAT
Protein: Galectin-4 (Gal-4) (Lactose-binding lectin 4) (Q8K419)
Organism: Mus musculus (Mouse)
Function: Galectin that binds lactose and a related range of sugars.
Interaction partners:
- ELAV-like protein 4
- 4-hydroxyphenylpyruvate dioxygenase
- TATA-box-binding protein
- E3 ubiquitin-protein ligase TRAIP
- SH3KBP1-binding protein 1
- CKLF-like MARVEL transmembrane domain-containing protein 7
- Cellular tumor antigen p53
- Sigma intracellular receptor 2
Sequence:
MAYVPAPGYQPTYNPTLPYKRPIPGGLSVGMSVYIQGMAKENMRRFHVNFAVGQDDGADVAFHFNPRFDGWDKVVFNTMQSGQWGKEEKKKSMPFQKGKHFELVFMVMPEHYKVVVNGNSFYEYGHRLPVQMVTHLQVDGDLELQSINFLGGQPAAAPYPGAMTIPAYPAGSPGYNPPQMNTLPVMTGPPVFNPRVPYVGALQGGLTVRRTIIIKGYVLPTARNFVINFKVGSSGDIALHLNPRIGDSVVRNSFMNGSWGAEERKVAYNPFGPGQFFDLSIRCGMDRFKVFANGQHLFDFSHRFQAFQMVDTLEINGDITLSYVQI
Protein: Growth/differentiation factor 5 (GDF-5) (Bone morphogenetic protein 14) (BMP-14) (P43027)
Organism: Mus musculus (Mouse)
Function: Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction (By similarity). Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG (By similarity). Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P43026}. Cell membrane {ECO:0000250|UniProtKB:P43026}.
Interaction partners:
- Bone morphogenetic protein receptor type-1B
- Bone morphogenetic protein receptor type-1A
- Bone morphogenetic protein receptor type-2
- Noggin
- Activin receptor type-2B
- Gremlin-2
- Activin receptor type-2A
- Chordin
- Neuroblastoma suppressor of tumorigenicity 1
- C-X-C chemokine receptor type 4
Sequence:
MRLPKLLTLLLWHLAWLDLELICTVLGAPDLGQRTPGAKPGLTKAEAKERPPLARNVFRPGGHIYGVGATNARAKGSSGQTQAKKDEPRKMPPRSGGPETKPGPSSQTRQAAARTVTPKGQLPGGKASSKAGSAPSSFLLKKTREPGTPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGNSSVKLEAGLANTITSFIDKGQDDRGPAVRKQRYVFDISALEKDGLLGAELRILRKKPLDVAKPAVPSSGRVAQLKLSSCPSGRQPAALLDVRSVPGLDGSGWEVFDIWKLFRNFKNSAQLCLELEAWERGRAVDLRGLGFERTARQVHEKALFLVFGRTKKRDLFFNEIKARSGQDDKTVYEYLFSQRRKRRAPLANRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR
Protein: Putative 2-hydroxyacid dehydrogenase C1773.17c (EC 1.-.-.-) (O94574)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Branched-chain-amino-acid aminotransferase, mitochondrial
Sequence:
MKQSRTKRVLAIGELKFATNTLKRLSEKYHFEFIVPDPHDRSKTIEKIHEAASKSTFDACFWLFRNAAISPFTEEMLGPLLPTCKLFVTGAAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRLGKWRQNLSLTDDPYGKRVGIIGMGAIGKSFAQKILPLGCEIVYHNRNRLEAEEEKRLGASFVSFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFTVAKTEECVLASIETFLDTGIPTNPVNGPFGMNGC
Protein: Fatty acyl-CoA reductase 1 (EC 1.2.1.84) (Q39152)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. Catalyzes specifically the formation of C18:0 and C22:0 fatty alcohols. Provides the fatty alcohols required for synthesis of suberin in roots, seed coat and wound-induced leaf tissue. Provides the fatty alcohols required for synthesis of alkyl hydroxycinnamates in root waxes.
Interaction partners:
- Wax ester synthase/diacylglycerol acyltransferase 1
- At5g22540
- Pentatricopeptide repeat-containing protein At4g33170
- RING-type E3 ubiquitin transferase
- Probable lysophospholipase BODYGUARD 3
- GDSL esterase/lipase At1g58430
- Cytochrome b561 and DOMON domain-containing protein At4g17280
- Nucleolar GTP-binding protein 1
- GDSL esterase/lipase At1g74460
- Brefeldin A-inhibited guanine nucleotide-exchange protein 1
Sequence:
MESNCVQFLGNKTILITGAPGFLAKVLVEKILRLQPNVKKIYLLLRAPDEKSAMQRLRSEVMEIDLFKVLRNNLGEDNLNALMREKIVPVPGDISIDNLGLKDTDLIQRMWSEIDIIINIAATTNFDERYDIGLGINTFGALNVLNFAKKCVKGQLLLHVSTAYISGEQPGLLLEKPFKMGETLSGDRELDINIEHDLMKQKLKELQDCSDEEISQTMKDFGMARAKLHGWPNTYVFTKAMGEMLMGKYRENLPLVIIRPTMITSTIAEPFPGWIEGLKTLDSVIVAYGKGRLKCFLADSNSVFDLIPADMVVNAMVAAATAHSGDTGIQAIYHVGSSCKNPVTFGQLHDFTARYFAKRPLIGRNGSPIIVVKGTILSTMAQFSLYMTLRYKLPLQILRLINIVYPWSHGDNYSDLSRKIKLAMRLVELYQPYLLFKGIFDDLNTERLRMKRKENIKELDGSFEFDPKSIDWDNYITNTHIPGLITHVLKQ
Protein: AT1G11360 protein (Adenine nucleotide alpha hydrolases-like superfamily protein) (C0Z2J1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Endonuclease or glycosyl hydrolase
- Calcium load-activated calcium channel
- Protein yippee-like At5g53940
- RING-type E3 ubiquitin transferase
- At5g19340
- Cytosolic sulfotransferase 11
- Arginine/serine-rich-like splicing factor
- Calcium-binding EF hand family protein
- Probable pectinesterase/pectinesterase inhibitor 25
- Calcium-binding EF hand family protein
Sequence:
MTSPGKSPRSDRKSPTVVTVQPSSPRFPISTPTAGAQRKIGIAVDLSDESAYAVQWAVQNYLRSGDAVVLLHVQPTSVLYGADWGAMDLSPQWDPNNEESQRKLEDDFDIVTNKKASDVAQPLVEADIPFKIHIVKDHDMKERLCLEVERLGLSTLIMGSRGFGATKRSSKGRLGSVSDYSVHHCACPVVVVRFPDDKDGEDEKSGDSGGENLMDSDKLHTVPEVAEEEGDKDEYHDASDKQ
Protein: Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein (Q9VY02)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Glucose dehydrogenase [FAD, quinone] short protein]
- Phosphoglucomutase 1
- Glucose-6-phosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase 1
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Phosphotransferase
- Phosphotransferase
- Hexokinase type 1
- Hexokinase type 2
- Glyceraldehyde-3-phosphate dehydrogenase
Sequence:
MSAINTFVAMWRFLLTLGPSAMIILLLNKGILEQRPDIVDEQHRVRSIHIEDLRESYDFIVIGGGSAGCVLAARLSENPEWSVLLLEAGGDEPLLIDLPQLYPVFQRSPWDWKYLTEPSDRYCLAMEDQRCFWPRAKVLGGCSSINAMMYIRGNRRDYDQWAALGNPGWNYDNILHYFRKLEDMRVPGFEHSPYHGHGGPISVERYRFPSPLLDIFMRAAQQLGMVHPDGDFNGRSQTGFAPPHGSLRDGLRCSANKGYIRRSWQRPNLDIVLKAFVERIVIDPQSHRAIGVIFEYGLLKHTVRAKREVILSAGSLASPQLLMVSGVGPRDQLEPQGIPVVQHLPGVGGNLQDHISTSGAIYTFDSGQNRHLSFIVPEMMNEQAVEDFVQGSDSFFYAMPVSEVMGFFSTRYQDPRLDWPDVQIFMGSYGYGADGGMIGRRGAAITLDNYAEAFEPVLYQDSFVIAPLLMRPRSRGYLQLRSADPKVHPLIHANYYDDPHDMAVMVEGLKLAHRLTQTPVMQSLNATMNIYEWRNCPEVEYLSDAFWECLARFYSQTIYHPVGTCKMAPASDPAGVVDPRLRVRGMRGLRVIDASIMPTIPTGNTNAPTLMLAERGADIIKEDWRHYRDGGWG
Protein: ABC transporter family-like protein (Q4Q3L0)
Organism: Leishmania major
Interaction partners:
Sequence:
MRLTDAPWFAIPLATVTAVRVVTAIVNLSNRRELRLRVGSRAARDAESLIDAVGRLADNTGDGVYPSTEDPTATVIDLNTTHRRIKVSRARLRSLSCGLLPLFDCYAVACRCGTVPDAAKADVWNCLCAVVEAHLQAYVSADALAANVSEAATALAMCEMLLERRYHVTRFLEAPLASSRLLLSTPPRHLLAEAVRKNRDESCTMRSLVLFARLLHNACTPPAKALLALLAVVNVTYISRLMCTTSSATVPSALRYTIDVLHEGTATGAAQFCTWRRFVRQVATSAPGRMLASATLGAVVSHLFNSAKEAASDAVLRRFHMTLKMDTLLALTRFDFVADAHWPLPGRVYSALGVVTNFSFADVDRLLDVVAERVQRWRTVWRLPVACMVGWLTRQGLDWLQRCWTRACLMTLFLVRYGAGEQGCCTAPRERVGGAECRLSLPLCRAHYGLQVLLLAAVSPSDTASASSAVVQFLAEHIRWPLSPRPCLRATKQVLRAVSTADGAVEVLRVRYNAVRELCASPAEDAQVPASFAATLSLRRASGDGLFLPPSWPSTLTMDFGILGGDVLEDVMNKVFSSSNGIPIMAAVAATEAQSRAQHGTTSLPPEDAVAAVYDVARVVDSGAVFVVPPARPWTLVSSFQFDVQTAQLHYDEHEAYTQSVATLVHVQHTHRPTLDGQPWAHYNTPPSLLCPRNDTSAAWRVTFDHVFFRYPGTERDVLHDITFDVAAGGFLGIVGYSGAGKSTLLLLLSRVYAPTQGHIRINGHPIECIPPRALRRRLGNCWQCDRDTCFLEGISVERNVAYGNLSAACGGAITAALQQACIDTAVAARPSGSREPLRCSEWSGGEVTRLMLARAFMVPADDAGVYMFDECTNGLDSVTEAKLFPRDLCRRRNATRIMVSHRLASVRVADEILVLAHGRIVERGTWAQLLRGGDDSFFCTLYRAQAVS
Protein: Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661) (Q9BSG1)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- CCHC-type zinc finger nucleic acid binding protein
Sequence:
MAAVSPTTRCQESVTFEDVAVVFTDEEWSRLVPIQRDLYKEVMLENYNSIVSLGLPVPQPDVIFQLKRGDKPWMVDLHGSEEREWPESVSLDWETKPEIHDASDKKSEGSLRECLGRQSPLCPKFEVHTPNGRMGTEKQSPSGETRKKSLSRDKGLRRRSALSREILTKERHQECSDCGKTFFDHSSLTRHQRTHTGEKPYDCRECGKAFSHRSSLSRHLMSHTGESPYECSVCSKAFFDRSSLTVHQRIHTGEKPFQCNECGKAFFDRSSLTRHQRIHTGESPYECHQCGKAFSQKSILTRHQLIHTGRKPYECNECGKAFYGVSSLNRHQKAHAGDPRYQCNECGKAFFDRSSLTQHQKIHTGDKPYECSECGKAFSQRCRLTRHQRVHTGEKPFECTVCGKVFSSKSSVIQHQRRYAKQGID
Protein: Probable thioesterase PNKD (EC 3.1.2.-) (Myofibrillogenesis regulator 1) (MR-1) (Paroxysmal nonkinesiogenic dyskinesia protein) (Q69ZP3)
Organism: Mus musculus (Mouse)
Function: Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000250|UniProtKB:Q8N490}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8N490}. Mitochondrion {ECO:0000250|UniProtKB:Q8N490}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000250|UniProtKB:Q8N490}. Mitochondrion {ECO:0000250|UniProtKB:Q8N490}.
Interaction partners:
Sequence:
MAAVVAATALKGRGARNARVLRGILSGATANKASQNRTRALQSHSSPECKEEPEPLSPELEYIPRKRGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAGLAVAVDPSDPRAVQASIEKERVNLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGTAETMLSSLDTVLDLGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRMERKSTCPSTLGEERAYNPFLRTHCLELQEALGPGPGPTSDDGCSRAQLLEELRRLKDMHKSK
Protein: Pentatricopeptide repeat-containing protein At4g32430, mitochondrial (Q84MA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Uncharacterized protein
- Pentatricopeptide repeat-containing protein At3g62470
- AT3g47961
- Transmembrane protein
- Dentin sialophosphoprotein-like protein
- Heavy metal transport/detoxification superfamily protein
- Alternative NAD
- ATP synthase subunit O, mitochondrial
Sequence:
MTLLNYLHCNRSKSFLFQRFYSPYRIAHKLFDGSSQRNATTSINHSISESLRRNSPARALSIFKENLQLGYFGRHMDEVTLCLALKACRGDLKRGCQIHGFSTTSGFTSFVCVSNAVMGMYRKAGRFDNALCIFENLVDPDVVSWNTILSGFDDNQIALNFVVRMKSAGVVFDAFTYSTALSFCVGSEGFLLGLQLQSTVVKTGLESDLVVGNSFITMYSRSGSFRGARRVFDEMSFKDMISWNSLLSGLSQEGTFGFEAVVIFRDMMREGVELDHVSFTSVITTCCHETDLKLARQIHGLCIKRGYESLLEVGNILMSRYSKCGVLEAVKSVFHQMSERNVVSWTTMISSNKDDAVSIFLNMRFDGVYPNEVTFVGLINAVKCNEQIKEGLKIHGLCIKTGFVSEPSVGNSFITLYAKFEALEDAKKAFEDITFREIISWNAMISGFAQNGFSHEALKMFLSAAAETMPNEYTFGSVLNAIAFAEDISVKQGQRCHAHLLKLGLNSCPVVSSALLDMYAKRGNIDESEKVFNEMSQKNQFVWTSIISAYSSHGDFETVMNLFHKMIKENVAPDLVTFLSVLTACNRKGMVDKGYEIFNMMIEVYNLEPSHEHYSCMVDMLGRAGRLKEAEELMSEVPGGPGESMLQSMLGSCRLHGNVKMGAKVAELAMEMKPELSGSYVQMYNIYAEKEEWDKAAEIRKAMRKKNVSKEAGFSWIDVGDTEGSLTMQGFSSGDKSHPKSDEIYRMVEIIGLEMNLEGKVAV
Protein: Afamin (Alpha-albumin) (Alpha-Alb) (P43652)
Organism: Homo sapiens (Human)
Function: Functions as carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier.
Subcellular location: Secreted {ECO:0000269|PubMed:12463752, ECO:0000269|PubMed:15952736, ECO:0000269|PubMed:26902720, ECO:0000269|PubMed:7517938}.
Interaction partners:
- Histidine-rich glycoprotein
- Beta-2-glycoprotein 1
- Protein Wnt-3a
- Serum amyloid P-component
Sequence:
MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN
Protein: High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R) (P17096)
Organism: Homo sapiens (Human)
Function: HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Transcription factor Jun
- High mobility group AT-hook 2
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- Small integral membrane protein 29
- Interferon regulatory factor 1
- Protein arginine N-methyltransferase 6
- Farnesyl pyrophosphate synthase
- Geranylgeranyl pyrophosphate synthase
- Phosphomevalonate kinase
- Interferon regulatory factor 3
Sequence:
MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRPRGRPKGSKNKGAAKTRKTTTTPGRKPRGRPKKLEKEEEEGISQESSEEEQ