wanglab/gogpt-training-data huggingface dataset:
Protein: C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1) (O60271)
Organism: Homo sapiens (Human)
Function: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q58A65}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q58A65}. Lysosome membrane {ECO:0000269|PubMed:29146937}. Note=Perinuclear distribution in response to stress signals such as UV radiation. {ECO:0000250|UniProtKB:Q58A65}.; SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:15693750}. Note=Associated with the plasma membrane of the acrosomal compartment and also localizes in the acrosome matrix. {ECO:0000269|PubMed:15693750}.
Interaction partners:
- ADP-ribosylation factor 6
- Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
- Hyaluronidase-3
- Hyaluronidase PH-20
- Kinesin light chain 1
- Hyaluronidase-2
- C-Jun-amino-terminal kinase-interacting protein 1
- Mitogen-activated protein kinase 8
- C-Jun-amino-terminal kinase-interacting protein 2
- DNA polymerase subunit gamma-1
Sequence:
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYEREKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEMIHNYMEHLERTKLHQLSGSDQLESTAHSRIRKERPISLGIFPLPAGDGLLTPDAQKGGETPGSEQWKFQELSQPRSHTSLKVSNSPEPQKAVEQEDELSDVSQGGSKATTPASTANSDVATIPTDTPLKEENEGFVKVTDAPNKSEISKHIEVQVAQETRNVSTGSAENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNIVKNDLIAKVDELTCEKDVLQGELEAVKQAKLKLEEKNRELEEELRKARAEAEDARQKAKDDDDSDIPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTTKKPEPPVNLKYNAPTSHVTPSVKKRSSTLSQLPGDKSKAFDFLSEETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGQGENKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYKDVAGLDTEGSKQRSASQSSLDKLDQELKEQQKELKNQEELSSLVWICTSTHSATKVLIIDAVQPGNILDSFTVCNSHVLCIASVPGARETDYPAGEDLSESGQVDKASLCGSMTSNSSAETDSLLGGITVVGCSAEGVTGAATSPSTNGASPVMDKPPEMEAENSEVDENVPTAEEATEATEGNAGSAEDTVDISQTGVYTEHVFTDPLGVQIPEDLSPVYQSSNDSDAYKDQISVLPNEQDLVREEAQKMSSLLPTMWLGAQNGCLYVHSSVAQWRKCLHSIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLSNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRKESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETNKTSGVPGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGESELLGEDLPLEPSVTKAERSHLIVWQVMYGNE
Protein: Notch homolog 2 N-terminal-like protein C (P0DPK4)
Organism: Homo sapiens (Human)
Function: Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signaling pathway in a non-cell-autonomous manner via direct interaction with NOTCH2. Also promotes Notch signaling pathway in a cell-autonomous manner through inhibition of cis DLL1-NOTCH2 interactions, which promotes neuronal differentiation (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:29856954, ECO:0000269|PubMed:33693509}.
Interaction partners:
Sequence:
MWICPGGGGGGGGGGGGGDREDARPAPLCCGRCWRSGCAARPPRMCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPETVRRGTELWERDREVWNGKEHDEN
Protein: Leucine aminopeptidase 1 (EC 3.4.11.1) (P34629)
Organism: Caenorhabditis elegans
Function: Probably acts as a digestive enzyme.
Interaction partners:
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
Sequence:
MTQVLVRNGIQAVGDGLTSLIIVGKKSVLKNVTFEGKFKEVAQKFVTDGDSWNSMISRIPASGRHPLHYELAHLITVPDASSRGNTPTNAHSIYKELKPINYPEDTKNVHFVLFAEYPDVLSHVAAIARTFCKFSMKTSGIRELNVNIDVVCDKLTNEDAVFLTDLSESVRETARLIDTPANILTTDALVDEAVKVGNATGSKITVIRGEELLKAGFGGIYHVGKAGPTPPAFVVLSHEVPGSTEHIALVGKGVVYDTGGLQIKTKTGMPNMKRDMGGAAGMLEAYSALVKHGFSQTLHACLCIVENNVSPIANKPDDIIKMLSGKTVEINNTDAEGRLILADGVFYAKETLKATTIFDMATLTGAQAWLSGRLHGAAMTNDEQLENEIIKAGKASGDLVAPMLFAPDLFFGDLKSSIADMKNSNLGKMDGPPSAVAGLFIGAHIGFGEGLRWLHLDIAAPAEVGDRGTGYGPALFSTLLGKYTSVPMLKQ
Protein: Protein ELC-like (ESCRT-I complex subunit VPS23 homolog 2) (Protein VACUOLAR PROTEIN SORTING 23B) (Vacuolar protein sorting-associated protein 23 homolog 2) (Q9FFY6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).
Subcellular location: Endosome {ECO:0000250|UniProtKB:Q9LHG8}. Prevacuolar compartment {ECO:0000269|PubMed:25438943}.
Interaction partners:
- Vacuolar protein sorting-associated protein 28 homolog 2
- Vacuolar protein sorting-associated protein 28 homolog 1
- Vacuolar protein-sorting-associated protein 37 homolog 1
- Vacuolar protein sorting-associated protein 36
- Vacuolar protein-sorting-associated protein 37 homolog 2
- Putative vacuolar protein sorting-associated protein 24 homolog 2
- Vacuolar protein sorting-associated protein 32 homolog 1
- Vacuolar protein sorting-associated protein 32 homolog 2
- Vacuolar protein sorting-associated protein 24 homolog 1
- Vacuolar protein sorting-associated protein 2 homolog 3
Sequence:
MAPPPAKMQEIHQFLSSALTQRGPSALPYAENTKSLIRQHLLNLISSYTSLDPKTATFTHNDGRSVILLQADGTIPMPFQGVSYNIPVVIWLLESYPQYPPCVYVNPTRDMIIKRPHSNVSPSGLVSLPYLQNWIYPSSNLVDLASHLSAAFSRDPPLYSQRRPPPQPSPSIGSGYSRPLPPRQTDDAAEVYKKNAINRIVEMVHGDIVLMRSAREVETEGLLSLQSDLKRREEEINNGFKEMVIEKETLEQQLQVIAMNTDVLGSWIRENQGKAKDLLVDLDVDDSFECIDSLSKQMLECTALDLAIEDVVYSMDKSFRDGSLPFDQYLRNVRLLSREQFFHRATAEKVREIQMDAQVASIAARLHS
Protein: FI07225p (Ski6, isoform A) (Ski6, isoform B) (Q9VK19)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Nuclear nucleic acid-binding protein C1D
- Exosome complex component RRP45
- Csl4
- FI06805p
- Exosome complex component 10 homolog
- Exosome complex exonuclease RRP44
- FI01414p
- Ribosomal RNA-processing protein 42
- Exosome complex component RRP4
- RNA helicase
Sequence:
MSGKYDLLSEQGLRLDGRRPHELRRIKCKLGVFEQPDGSAYMEQGNTKVLAAVYGPHQAKGNQTESVINCQYSQATFSTAERKNRPRGDRKSLEFKLYLQQALSAAIKSELYPRSQIDIYVEVLQDDGANYAVALNAATLALIDAGICLNEFIVACTASLSKSNIPLTDISQFEEVSGGPKLTVAALPTAEKIAFLEMSERFHIDHLETVIETAMAGCREIRDILEAAVKEHLLHMGSASDFAKVG
Protein: Cyclic AMP receptor protein (Cyclic AMP receptor protein/Fumarate and nitrate reduction regulator superfamily protein TTHA1437) (CRP/FNR superfamily protein TTHA1437) (cAMP receptor protein) (CRP) (Q5SID7)
Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Function: Activates transcription. Positively regulates six promoters upstream of the TTHB186, TTHB147, TTHB178, TTHB159, TTHA0771 and TTHA0176 genes in a cAMP-dependent manner. Regulated genes include clustered regularly interspaced short palindromic repeat (CRISPR) associated (Cas) genes, and the genes encoding a putative transcriptional regulator, a protein containing the exonuclease III-like domain of DNA polymerase, a GCN5-related acetyltransferase homolog, and some T.thermophilus-specific proteins of unknown function. The consensus DNA-binding site of this transcriptional regulator is 5'-(CT)NNG(G/T)(G/T)C(A/C)N(A/T)NNTCACAN(G/C)(G/C)-3' in which N is G, A, T or C.
Interaction partners:
Sequence:
MKGSPLFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQERTLALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALIRRLPLVAHNLAALLARRLREADLELDLLSFEEARNRVAYALLKLLRQGLGPLFQIRHHELAALAGTSRETVSRVLHALAEEGVVRLGPGTVEVREAALLEEIAFGLA
Protein: Uncharacterized protein YLR363W-A (Q3E747)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Nonsense-mediated decay protein 4
Sequence:
MPQKPLKVTKKAKDPRRVTKKQKNLRKAAPLQLKSKKKSLQHLKKLKKSSSLTETTERLVASKVGHLELLRGTRKELEKGKKNSK
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (Q8AVL7)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
RRAEKQEAKNSSDRQTDRQTDRQTDMGVDLETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFKIGRQEVIKGWEEGVAQMSLGQRAKLTCSPDVAYGATGHPGVIPPNATLIFDVELIRIE
Protein: START domain-containing protein (Q38BX2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWDVVSRVGKAAYRTAALTGLAAGTEQPPYPCALPLKTVSSDSDVDSMREVLNSAFDASKDMLENNGEHQWQLVDYVDPEEGGDLHLFTRPRVGPFNFVKATLSFMGVSPQNVLDTMHSDNADDRKRYSANLSHFEVLAKPMAGCAIELHKYWAPPPVAGREFVFAAEKKYVESENVYYVHGCSIDYTPQMETSKGFVRAACLWAWKLMPVGDNTLATYVSCMNPRGWTPPFIFGWLKSEIGKELVACRRVLYGETVKVERTTLQGMGLSDEVNNLTDEERKRMSEGEPQPEAS
Protein: Globin domain-containing protein (A3RMS5)
Organism: Caenorhabditis elegans
Interaction partners:
- Neuropeptide receptor npr-1
- Globin-like protein 26
- Soluble guanylate cyclase gcy-35
- Soluble guanylate cyclase gcy-36
- Globin-like protein 6
- RNA cytidine acetyltransferase
- Globin
- Globin-like protein
- Globin domain-containing protein
- Globin-like protein 9
Sequence:
MNETTVGVGKMYEEFRITQLVNETLTTVIEKVQTNHEKISTKAKPRPLSAINEEIREYDQLSRELEKDYRRSMRIVDDDFELARTHWIQLQKSNKQGLAIRGCFLTMLEKYPQVRPIWGFGKRIEGRGDETWKPEIVEDFYFRHHCASLQAALNMIIQNKDDKSGMRRMLNEMGAHHFFYDACEPHFEVFQDSLLESMKLVLNGGDSLDDDIEQSWICLLQTIRLHMGEGIEIQRANYLTQCLIPKEMEEVRANWMQVENYGFRKAGLLLCQSAFDNYSELLKTHNLSMTLPIEANKTSDSFVALSDQIMQALDKTIQSYTPEEGFLNLIQEIKDFVIKFLVVEVCPPLIRKSFIDGLIHMLCKILSIKHVKEDFLHIWKKVYRVMEQAMVANIVEY
Protein: Receptor-binding cancer antigen expressed on SiSo cells (Cancer-associated surface antigen RCAS1) (Estrogen receptor-binding fragment-associated gene 9 protein) (O00559)
Organism: Homo sapiens (Human)
Function: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:12672804}; Single-pass type III membrane protein {ECO:0000269|PubMed:12672804}. Note=According to PubMed:10426319, it also exists as a soluble form which has the same biological activities. The existence of such soluble form is however uncertain.
Interaction partners:
- Estrogen receptor
- Cytochrome c oxidase subunit 7A2-like, mitochondrial
- Glutamate receptor ionotropic, NMDA 2D
Sequence:
MAITQFRLFKFCTCLATVFSFLKRLICRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEWTSWDEDAPTSVKIEGGNGNVATQQNSLEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGIPDGSTGFSSRLAATQDLPFIHQSSELGDLDTWQENTNAWEEEEDAAWQAEEVLRQQKLADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS
Protein: I[[h]] channel, isoform H (B7YZE9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYVSTSGSFWQRSVL
Protein: Myoglobin (Nitrite reductase MB) (EC 1.7.-.-) (Pseudoperoxidase MB) (EC 1.11.1.-) (Q9QZ76)
Organism: Rattus norvegicus (Rat)
Function: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Subcellular location: Cytoplasm, sarcoplasm {ECO:0000250|UniProtKB:P02144}.
Interaction partners:
- Neuroglobin
- Albumin
- Thyroglobulin
- Cytochrome c, somatic
- Creatine kinase S-type
- Haptoglobin
- Cytochrome b5
- Glycogen phosphorylase, muscle form
- Cytochrome b5 type B
- Myosin light chain 1/3, skeletal muscle isoform
Sequence:
MGLSDGEWQMVLNIWGKVEGDLAGHGQEVLISLFKAHPETLEKFDKFKNLKSEEEMKSSEDLKKHGCTVLTALGTILKKKGQHAAEIQPLAQSHATKHKIPVKYLEFISEVIIQVLKKRYSGDFGADAQGAMSKALELFRNDIAAKYKELGFQG
Protein: Protein YdgA (P77804)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:16079137}; Peripheral membrane protein {ECO:0000269|PubMed:16079137}; Periplasmic side {ECO:0000269|PubMed:16079137}. Note=Has been isolated in association with the inner membrane, suggesting it may be tethered to the membrane.
Interaction partners:
- Mannose-6-phosphate isomerase
- Phosphotransferase RcsD
- Penicillin-binding protein activator LpoB
- Probable phospholipid transport protein YdbH
- Uncharacterized serine protease YdgD
- Protein AsmA
- Cell division protein FtsN
- Membrane-associated protein UidC
Sequence:
MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQLKLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFPLAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLKPLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLKTDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQLDYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELYQEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLAQEVDRSVKSLDAKLTIPVDMATEFMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFRLTTLQDNTITTSLQYANGQITLNGQKMSLEDFVGMFAMPALNVPAVPAIPQQ
Protein: Extracellular serine/threonine protein kinase FAM20C isoform X1 (Family with sequence similarity 20 member C,-like) (Q1MTC0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
- UDP-glucuronic acid decarboxylase 1
- Xylosyltransferase II.
- FAM20A golgi-associated secretory pathway pseudokinase.
Sequence:
MRVCTRRRSLTLRVWLLIVFLSLHLLVVSLVLSVYHTSCELPSTYGIQTTISFSTQNASTSEITMATTRSVSKEMKMVDPTGDLAKLDALFSHPLYNLPTPPVPDGDWLLKVRTKVKEQERSTQQWVSANDDGFDPILWNTSTDTHPPWLRFHLGISRWQMYQHKDPNLSALNQQLASHRIVSAVQKSGGTQLKLVMSFPNYGQALFKPMKQERHEETNVNLYYFSDFERHNAEIAAFHLDRILGFRRIPPVIGRLINVIKEIKEVTTDHKLVTTFFNSPVGNTCFHGHCSYYCSTEHAVCGRPIKLEGSLAVMLPDLSLAPRHSWRSPWRRSYSRTNQAEWETNSNYCDTVKQTPPYDRGTRLVDVIDMSILDFLMSNMDRHHYETFEKFGNDTFLIHLDNGRAFGRHSKDEPSILAPLVQCCRVRRSTLLRLRLLSLPPYRLSDVMRASLSRDPLAEVAPLLTEPHLSALDRRLETVMQAIQDCLQQHQHHSDVIYDDIMDYPQA
Protein: Uncharacterized protein (Q38A93)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MIPVAGRRKGLSQAPNLGSAGNNETNSSLGGGFTTSTGAAPSPATAGDALSFLDFDNDTGPTQASAPVASRRGAPTAAPPQRDTLSFLDFDDDEGPSKPSAPAASRRTAPPVAPAPAQSAPSFLDFDDDDGPTKPPPRSQPPASAASRGAPAQAVPSFLDFDDDAPANVPSTPQPSAAVSLEITNRWHELQKELQRVQVETLSCEEVIRKFESGEHELCLEVGTLDEQVQQKQAAGEKAAAAREELERALELRRQQLTEENEAKHKQLLVEGVNTMRERYEDELSTLTASVEDQKVNLLAVEEKHSTMDGSISSVELYERAVCQLQERLKATLRDISAAVCLRIKPSLTNCIRDTVAQFAQERSDMQCNDRRRRREQLDTFQKNVDKGFSSFCEERRTKHQSRVDSIFGGERFRFQAEVERRFTTSRMEFMERQKELTAEAKKGALITFEEMTRRAAADMEVFQRKMKEELRLMEERYAAELAHLARLQASEKAAALRPRCENDELGSSVTAATPSVCKAVEKDVRYLRERVEQIKQSVSLDIQDLSIASQHPRCESLSALGKERMLAELEEKVRLLSRQFGAQWQRFKSAVGPLHQSVQLMVRGLQDGRVRAAAQQQETECIYREWTQSVRKELSMCLTSGGASSESAELQSGLVSMTRVVEMARAQVQAVLEAQRHRSEVLRGFNSEVQESLSALVKQRVASNGTLHSVFDEYERLSHAAAEVEAKRRALEVAAENYDHAKQVLEKERETFDGRLKVAQELGVKLRIDSEKLERKAARYARARLSGGSQFVRAVTMEKPLRDRLQCGKRMEWRSQSHGHSPRKRAADCVSGHPSPSSAEYRRSATASNGGDVLDFVTLLSFDDAVGQGDSGDLQHKRQPCQYRSTTSFDPSSCGSDGTYFTTPSTLN
Protein: Olfactory receptor 4C12 (Olfactory receptor OR11-259) (Q96R67)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MEKKKNVTEFILIGLTQNPIMEKVTFVVFLVLYMITLSGNLLIVVTITTSQALSSPMYFFLTHLSLIDTVYSSSSAPKLIVDSFQEKKIISFNGCMAQAYAEHIFGATEIILLTVMACDCYVAICKPLNYTTIMSHSLCILLVAVAWVGGFLHATIQILFTVWLPFCGPNVIGHFMCDLYPLLKLVCIDTHTLGLFVAVNSGFICLLNFLILVVSYVIILRSLKNNSLEGRCKALSTCISHIIVVVLFFVPCIFVYLRSVTTLPIDKAVAVFYTMVVPMLNPVVYTLRNAEVKSAIRKLWRKKVTSDND
Protein: Pheromone-binding protein 2 (PBP 2) (Q95VF0)
Organism: Epiphyas postvittana (Light brown apple moth)
Function: This major soluble protein in olfactory sensilla of male moths serves to solubilize the extremely hydrophobic pheromone molecules such as bombykol and to transport pheromone through the aqueous lymph to receptors located on olfactory cilia.
Interaction partners:
Sequence:
MMNHKELVLFAVVCLSLYQAVEPSQDVVKDMSLNFRKGLDACKKELNLPDTINSDFNRFWNDDHVVTNRDTGCAIMCLSSKLELVSDTGLHHGNTLEYAKQHGADDTVAQQIVDLLHSCAQAVPDLEDPCLKVLEWAKCFKAEIHKLNWAPSAEVMAAEMLAEV
Protein: phosphopyruvate hydratase (EC 4.2.1.11) (A8JH98)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Interaction partners:
- Pyruvate kinase
- Chloroplast triosephosphate isomerase
- phosphoglycerate mutase
- Glucose-6-phosphate isomerase
- Uncharacterized protein
- Uncharacterized protein
- transketolase
- Phosphoglycerate kinase
- glyceraldehyde-3-phosphate dehydrogenase
- fructose-bisphosphate aldolase
Sequence:
MSVQEYIEKHGLEKKVEEVLNLCVKEKPEEPLSFMAKALGQLTPPEIVKVVGRQIIDSRGNPTVEADVYTRKGMFRAAVPSGASTGVHEAVELRDGDKSKYLGKGVTKAVENINAIIAPALKGMDPVKQAEIDQKMKDLDGTDNKGKLGANAILAVSMAVCKAGAAEKGVPLYKHIADLAGNSKLILPVPSFNIINGGSHAGNALAMQEFMILPVGASSFSEAMRMGCEVYHALKGLIKAKYGQDACNVGDEGGFAPNIGSNDEGLNLVNEAIEKAGYTGKVKIGMDVASSEFYTEDGMYDLDFKNQPNDGSQKKTKEQMLELYNEFCKKYPVISIEDPFEQDDWEPCAKLTTENICQVVGDDILVTNPVRVKKAIDAKAVNALLLKVNQIGTITESIEAVRMAKEAGWGVMTSHRSGETEDSFIADLAVGLASGQIKTGAPCRSERNAKYNQLLRIEEELGENAVYAGESWRHIGW
Protein: Uncharacterized protein YOR296W (Q08748)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
Sequence:
MNRTVSTLSSTVSDVSVEIPSICNVINTELPTSDVYLYTLKLILLDYINEPRFKEAALLSNRTGTSRVLSDKTNHQQTQHGKKLVVDKQDDMSERDIVQATLRILKGKLAQISGNKNLAPNEMHWKSIVKMYYSMLDSSSADTFSKMGQMEEVVGYFTNIASNELKKMTIKNSRDELFSEVAYFIDLVIDVLPDSCANIIKRLLDYKINLKKGETTVKKKRAASPATVPQYRSISGSTISNKQPSFKVQDISHMKYFMQLFETDETKLHQDVMAVKDDCTNPIFCGELRYLRKKIKKDNGTLTASDFSSDREYNLWKNYELLEIANLMDRFEIGEKVTSHGNRLIPKDAKSVFVRLIGLVLKKECSNAVNAINLSQEALFFFHKSARYWRIEYPSTISSLVYSAANLSVLGDEELNIPITENLFSVIRNKYLCSEDNLDPSAWNAQDRYLWAANLFHTTDQSMRTINNLLTAIFSGTKPKFSPVLSFYYSNIVGDPVMEFYETQSVAVKKYWIKLFKKTLFKASEDYFVSLLQDMLKANAIEIQNVQNLVETIIEAIKAIQKRYNKPLLDEISLPRQCAVFLCEVYGSDSLNLIKTAEKSTMKMTGQKLGPIDALDMYDVLKELRQIYLQVKPKGKFFFNLENYFIKYLTRLCDDVSRNVQKVIKSSLESENWQPVNDQDHFSRSVLDIFKMINESTSMLEKFGWQNEFQLAQMITVILKAFSDGMLSYSAQLMELIQRDLQEGDEPSYSLESSDTRSSLSLNNANVNHEKSRSSRLFEDLKNVVKSTPKMVAPAPYQFKKRTCVLLNDLDKTLFLLESFEEKADPSKISSVIAQYHSSHNLEDNGKSFDDQNMKQVYTLRIIGAENIKGFSKTGLSNTYVSMRNITLQREIGTTKIVARSITPKWDEEFVFESPFGKSNDIMFTIWHHPHSRLKNLAEDDLCGKANMKFTPRKLKDDGFPIDFSLTLNPQGTLYCQISLESEKIDAVSSMGRIYRSFSRSRDRAINLIVNKFSDFIAFAFSRTTLKTVCGHHGSALASDEAVYDAILPLFDYLNANLNILASELSQRLLFMVMLRAWNLVLENADLLLLPALNSAKVNILRSAKKSLWENTLSTTKTVSGYGRPLTQAEIEAVFKWLDALCVDFFHNKGEGPPLAELKNEYYQNILLIPAFYDKSVSELKDEVQRLIPLYEEYLRWFYLKKTPITFTNKSAGTISRKKSLVANIVKEPKEQLERDAEVMNIILRILIAKGQHDYVHRILHDRKELVNTMKNRRAVSRAVTPTGKKGRN
Protein: Protein kinase byr2 (EC 2.7.11.25) (MAPK kinase kinase) (MAPKKK) (Protein kinase ste8) (P28829)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Serine/threonine protein kinase involved in conjugation and sporulation. It is thought that it phosphorylates the byr1 protein kinase which itself phosphorylate the spk1 kinase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12242289}. Cell membrane {ECO:0000269|PubMed:12242289}.
Interaction partners:
- Protein kinase byr1
- Ras-like protein 1
- Protein kinase wis1
- Serine/threonine-protein kinase shk1/pak1
- Sexual differentiation protein ste4
- Guanine nucleotide-binding protein alpha-1 subunit
- Cell division control protein 42 homolog
- Transcription factor ste11
- Mitogen-activated protein kinase spk1
- Rho guanine nucleotide exchange factor scd1
Sequence:
MEYYTSKEVAEWLKSIGLEKYIEQFSQNNIEGRHLNHLTLPLLKDLGIENTAKGKQFLKQRDYLREFPRPCILRFIACNGQTRAVQSRGDYQKTLAIALKKFSLEDASKFIVCVSQSSRIKLITEEEFKQICFNSSSPERDRLIIVPKEKPCPSFEDLRRSWEIELAQPAALSSQSSLSPKLSSVLPTSTQKRSVRSNNAKPFESYQRPPSELINSRISDFFPDHQPKLLEKTISNSLRRNLSIRTSQGHNLGNFGQEILPRSSRRARPSELVCPLSSLRISVAEDVNRLPRIDRGFDPPLTVSSTQRISRPPSLQKSITMVGVEPLYQSNGNEKSSKYNVFSESAHGNHQVLSFSPGSSPSFIEQPSPISPTSTTSEDTNTLEEDTDDQSIKWIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGENILPEFPSNISSSAIDFLEKTFAIDCNLRPTASELLSHPFVS
Protein: Putative uncharacterized protein FLJ37218 (Q8N1Y9)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAKWVPALLLRRVPLFSLRFRPASSTFLPVLAATEPAVSVPSGDLSMPVKTRAEGEDDGFGEAGDPRRLLERPWRFRGCLPGKGNRDVGFEGTEGPTSTRPEWVWSCRCCLGCRASTRERVTSPVRAAGPQPRFTDRETEAAAGTLAHMGFAPPTSFSHFTDQELRDCSSLECLGVVEGDPHVLCSTLSLSRPSPSATLTLLLASSCLLAPAPPSFILLLFTLIAPDLPHS
Protein: PHD finger protein 11 (X6RH80)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEE
Protein: NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) (E1AVU6)
Organism: Gallus gallus (Chicken)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|HAMAP-Rule:MF_03212}; Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_03212}; Cytoplasmic side {ECO:0000256|HAMAP-Rule:MF_03212}.
Interaction partners:
Sequence:
MGDAGMESTVSPPEGTAQDSFLSMTDVFLISLITGLFTYWFFFRKKKEEIPDLPKIHTVSSPARDSSFIEKMKKTGRNIVAFYGSQTGTAEEFANRLSKDAHRYGLRGMAADPEEYDLSDLSRLSEIDKSLAVFCMATYGEGDPTDNAQDFYDWLQEADTDLSGLRFAVFGLGNMTYEHFNAMGKYVDKRLEELGARRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESSIRQYELVVHTDVNMNKVYTGEMGRLKSYENQKPPFDAKNPFLAVVTENRKLNEGGERHLMHLELDISNSKIRYESGDHVAVYPANDASLVNQLGEILGTDLDTVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRTNVLHELAQYATDTGEQEQLRKMASSSAEGKALYLSWVVEARRNILAILQDTPSLRPPIDHLCELLPRLRARYYSITSSSKVHPNSIHICAVTVEYETKTGRLNKGVATNWLKDKVPNENGRNSLVPMYVRKSQFRLPFKPSTPVIMIGPGTGIAPFIGFIQERAWLKEQGKEVGETVLYYGCRREREDYLYRQELARFKQEGVLTQLNVAFSRDQAEKVYVQHLLKKNKEHIWKLVNDGNAHIYVCGDARNMARDVQNTFYEIVSEYGNMNQSQAVDYVKKLMTKGRYSLDVWS