wanglab/gogpt-training-data huggingface dataset:
Protein: 2-oxoacid:ferredoxin oxidoreductase 2, subunit beta (OFOR2) (EC 1.2.7.11) (Q96XT4)
Organism: Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
Function: Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
Interaction partners:
- 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha
- 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha
- 2-oxoacid oxidoreductase
- pyruvate synthase
- pyruvate synthase
- 2-oxoacid oxidoreductase
- Pyruvate kinase
- Succinate--CoA ligase subunit alpha
- Succinyl-CoA synthetase beta subunit
- Citrate synthase
Sequence:
MVERKPVFVDWCPGCGDFGILRAEEMAIRELGINPKSVVIVSGIGCSGKIPHFMNLPISGVHTLHGRSIAFATGIKLSNPSLEVIVNVGDGDGLGIGMGHFVHLGRRNIDIAVLVHNNGVYGLTKGQASPTLHRGEKTKSLPKPNIMDAVNPLAVALAAGYTFVARGYAYDVMHLKELIKKAILHKGSALVDILQPCPTYNDINTKEWYDKRVYKLDNVPGWDPVVRKEEEAQKKFEQAIMKSYEWGEKIPIGIFYQNELVPTFEDRLTSNIPNYREYYPAKQQIEINGISTTKIDELIKAKRI
Protein: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) (Malate dehydrogenase [quinone] iron-sulfur subunit) (EC 1.1.5.-) (P21912)
Organism: Homo sapiens (Human)
Function: Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:37098072}; Peripheral membrane protein {ECO:0000269|PubMed:37098072}; Matrix side {ECO:0000269|PubMed:37098072}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Fumarate hydratase, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- Succinate dehydrogenase cytochrome b small subunit, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- Succinate dehydrogenase assembly factor 2, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial
Sequence:
MAAVVALSLRRRLPATTLGGACLQASRGAQTAAATAPRIKKFAIYRWDPDKAGDKPHMQTYEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV
Protein: Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity-regulated gene) (p53-inducible protein U) (PIG-U) (Q8IXH6)
Organism: Homo sapiens (Human)
Function: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Subcellular location: Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.
Interaction partners:
- Gamma-aminobutyric acid receptor-associated protein-like 2
- GABA type A receptor associated protein like 1
- Vacuole membrane protein 1
- Gamma-aminobutyric acid receptor-associated protein
Sequence:
MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY
Protein: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Q5W015)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQPLLGQACL
Protein: Troponin C, slow skeletal and cardiac muscles (A0A8J8XJV6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MLKVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKMMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
Protein: Stevor (C6KT16)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MNIYYVKILIFTFLVNTLILSHNENCQNNQYNISLIKNNTQRTTIKPRLLAQTKNHNPHYHNDPELKEMIDKLNKEAIKKYQKIHEPYEQLQELVEKKGTKPVGEHGTEPMSTIEKELLETYEKMFGDKKDIMLKSGMPPNDDDRSDKSITCECTDINNPDLTKAKSKDKYLKRLKEGCTRGICTCSVGSAFLTLIGLAAAKKAAVAAFSAPYDACVSSTSLFYIFDSGTLASALKVGSTCASVATDMAGTVSSAATTAIIPFSISIYVLIVITVLLIILYIWLYRRRKNSWKHECKKHLCK
Protein: Cytochrome P450 monooxygenase (Q2TW05)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Interaction partners:
Sequence:
MDLMLALITLSLVEGFLLQRTVFVDLTFRTVTLSSVGVNLVLLTIWNTLIYPYFVTPLRHLPTISGNLNNARIVFDDPRGRLPLEWMKTVPNEGLIHFRDIVNRSYLLATNHQALLDIMSTNTYDFEKPWRARDFLARIIGFGLILSEGSAHKKQRRALTPSFNVKNIRALYSLMWEKTGLLMDELEKQIKQNPMDGTNAQSGEGKIEMSVWASRLTLDIIGPAAMGRDFRSLHNPENKVADSFLAILEPTKEKMAFLAVNFALPQWFARRIPWRLNKVINDETGFLRDLCRDIVHEKRASITATKATAKELEADILGTMMLGGDFTDDELIDQMLTFLAAGHETTASAFTWACYLLTLYPDVQERLRTEIRERIPSGNHPITWSDLETLPLLNGVCQEVLRLYPTVPMTIREAVRDSVVAGKHIPKGTRILLCPYAINRSPEFWGNDGEEFRPERWIDTDKNGQLVTNNTGGASTNFAQITFLHGQRSCIGKDFARAELRCAVAGVVGRFRFEMQNPKQKIHIAGAVTTKPVEGMHLRMSRVDDW
Protein: cDNA FLJ53174, highly similar to Numb-like protein (B7Z5W0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGDLQKTFEIEL
Protein: Major centromere autoantigen B (Centromere protein B) (CENP-B) (P27790)
Organism: Mus musculus (Mouse)
Function: Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P07199}. Chromosome, centromere {ECO:0000250|UniProtKB:P07199}.
Interaction partners:
- Histone H3-like centromeric protein A
- Centromere protein S
- Centromere protein H
- RNA-binding protein Ro60
Sequence:
MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVACSGVTRSRARSSAPRAPAAPAGPATVPSEGSGGSTPGWHTREEQPPSVAEGYASQDVFSATETSLWYDFLSDQASGLWGGDGPARQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQGGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLGLVEALHFVAAAWQAVEPSDIATCFREAGFGGGLNATITTSFKSEGEEEEEEEEEEEEEEEEEGEGEEEEEEEEEGEEEGGEGEEEGEEEVEEEGEVDDSDEEEEESSSEGLEAEDWAQGVVEASGGFGGYSVQEEAQFPTLHFLEGGEDSDSDSDEEEDDEEEDEEDEDEEDDEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS
Protein: Small ribosomal subunit protein eS12y (40S ribosomal protein S12-2) (Q9SKZ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein eS28x
- Small ribosomal subunit protein eS1y
- Small ribosomal subunit protein eS21y
- Small ribosomal subunit protein eS24y
- Small ribosomal subunit protein uS12y
- Large ribosomal subunit protein uL18y
- Small ribosomal subunit protein eS6y
- Small ribosomal subunit protein uS2z
Sequence:
MSGDEAVAAPVVPPVAEAAVIPEDMDVSTALELTVRKSRAYGGVVRGLHESAKLIEKRNAQLCVLAEDCNQPDYVKLVKALCADHSIKLLTVPSAKTLGEWAGLCKIDSEGNARKVVGCSCLVIKDFGEETTALNIVKKHLDSN
Protein: leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (A0A6I8PL42)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAESPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVLMENIVYLTNSLELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGDTIIYLVH
Protein: Thrombospondin-3a (Thbs3a) (Q8JHW2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen (By similarity).
Interaction partners:
- Platelet glycoprotein 4
- Syndecan 4.
- Integrin alpha-5 precursor
- Integrin, alpha 10
- Integrin alpha-11a precursor
- Integrin alpha-2 isoform X1, tandem duplicate 2)
- Tetraspanin.
- Integrin, alpha 6,-like
- Integrin alpha-9
- Integrin, alpha 6b
Sequence:
MEQMFVHIWVSLVVLMSVWSAQSDKKQDVPVIDVLGLEDVKQTVAAVEKLSLALKTLSDVYVMSTFRLPPKLGGVLLGLYNKQDNKKYLEVAIMSKINKVLVRYVREDGKLHTVNMQSPNVADGRPQSLILRVGGLRREYLSLELYVNCRLADSAQRLPPLVDLPRDAELVEIRNGHKAYARMQGSMDTLKLALGGTVAQAGALTDCPFQGDASSYNIVNGEVNSILGDHTKALIGQLIIFNQILGELREDIREQVKEMSLVRNAILECQMCGFHEPRSRCQPNPCFKGVSCMETFEYPGYRCGPCPDGMTGNGTHCQDIDECSEAQPCYTPGACVNTARGFTCESCPPGMWGPPLSGVGVEYAKSHRQECSDIDECVDLANACTPNSVCINIIGSFRCGQCKTGYVGNQTAGCFPRKSCSSLSFNPCDANAHCVMQRNGDVSCACNVGWAGNGHTCGKDTDIDGYPDRSLPCMDNHKHCRQDNCVYTPNSGQEDADNDGIGDQCDEDADGDGIKNVEDNCRLVSNKDQQNSDTDSFGDACDNCPTVPNIDQKDTDSNGEGDACDDDIDGDGIQNVLDNCPKVPNPMQTDRDRDGVGDACDSCPEISNPMQTDVDNDLVGDVCDTNQDTDGDGHQDTRDNCPDIPNSSQLDSDNDGIGDDCDEDDDNDGIPDNHAINGIGPDNCRLISNPNQKDSDSNGVGDVCENDFDNDSVMDLVDVCPESAEVTLTDFRAYQTVILDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDCAGSIFGYQDSSSFYVVMWKQTEQTYWQSIPFRAMAEPGLQLKAVKSRTGPGEFLRNALWHAGDTDGEVKLLWKDPRNVGWLDKTSYRWQLSHRPQVGYIRVKLYEGSEMVADSDVVIDTSMRGGRLGVFCFSQENIIWSNLRYRCNDTVPEDFSSHRKQVLMHIKV
Protein: Acidic leucine-rich nuclear phosphoprotein 32 family member (A3RL83)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU369103}.
Interaction partners:
Sequence:
AAGSARLGSGGLAFSSARFGSAQAGTGGGRMEMKKRLTLELRNKKPGEVKELVLDNCRSDDGKIVGLSSDFENLEFLSMINVNLLSISNLPKLNKLRKLELSDNRISGGLEVLAERTPNLTHLNLSGNKIKDINTLEPLKKLPNLHSLDLFNCEVTMLINYRESVFTLLPQLTYLDGFDADEQEAPDSDPEADGDGLEDEYENGEEGEEEEDDDEEDDLDEEVIDEEDDEDDDLEGEEEEDGVDDEEEDEEEDGEDEGDDEADDDLPRGEKRKRNLEDEGEEDPEDEEDDEDD
Protein: tissue kallikrein (EC 3.4.21.35) (A0A0G2K6G1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MWFLILFLDLSLGQIDAAPPGQSRVIGGYKCEKNSQPWQVALYSFSKYLCGGVLIDPSWVITAAHCSSNNYQVWLGRNNLLEDEPFAQHRLVSQSFPHPDYKPFLMRNHTRKPGDDHSNDLMLLHLSQPADITDGVKVIDLPTEEPKVGSTCLASGWGSTKPLIWEFPDDLQCVNIHLLSNEKCIKAYKEKVTDLMLCAGELEGGKDTCTTLGFLPYGSDVSWEGRILELVLFLLIDLASGTGLSTPHSL
Protein: E3 ubiquitin-protein ligase bre-1 (EC 2.3.2.27) (RING finger protein rfp-1) (RING-type E3 ubiquitin transferase bre-1) (P34537)
Organism: Caenorhabditis elegans
Function: E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-117' of histone H2B (By similarity). H2B 'Lys-117' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (By similarity). Involved in regulating stem cell proliferative fate.
Subcellular location: Nucleus {ECO:0000269|PubMed:14732404}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 1
- SWIM-type domain-containing protein
- E3 ubiquitin-protein ligase ubr-1
- Glycosyltransferase-like protein LARGE
- RNA polymerase-associated protein RTF1 homolog
- Suppressor of Ty 6 homolog
- TPR_REGION domain-containing protein
- Cell division cycle protein 73
- RNA polymerase II-associated factor 1 homolog
- Histone-lysine N-methyltransferase
Sequence:
MMKRSNEGIGGENYASSPSDDGQQKRRKIQFEPVRMPAVSNVNDIRARAVVYQTSKLKQQLLYKNKRIAELEKENERSKRRQQTDESNFLKVYNMFSDIEKYICTQTKNEFGEYIGGDTAPTGIDVLGMTNETYNKFFDQAKQNLRNAFVSYAKARHDRAHESTIFIDKLKTLIDSPTFNPNGVHKELTAKAASLAIQNEKLQSEVTKVQSDCYNLERKKRILTDKLSVQENRVQELEHQLEDARFETDKHMRLANKFEYKLATLVSEGQSGGNGGATPSSSGTTNATEKKISAPDIPPSETAAKEIENLRLERDEQESIASRRLQDLEEMNKKVQTLTQENSKLRLETQTFFSVDSIVNSEEYKNLKKYYSLAIKEYERVSKDLEDITTERDAFRSAKEARAMLMSEEHQKTLKEIQCQSDIHNSFYKVSHDSEVLRCEFETVKEEYNKTVKQSEWDEMKATLNTLRSMNRSLKSEKIRLREKDKQSQKDINTLKSELTSLKEAQDKCLLVPLEDVSNAPPEDVNKIRQEYESLCKEVKRLGAMEKQEKQKQVENLQKEVNRQIADKLSELETLRKTNEMLTNDEECISDELEAIGTAVEEEQERNAQLYIEKREQEDRNLKMMNDRMIQNQTFNRLREKLSCLESKAQTDAQIAKMHEFEKKANEELVTKLSESVQFKSAELTRLTNLMEQHRKNIQEVGMSRDENQIKADRCEGQMKQIQELYAAKAREIEDFKFKRQRAEEELETLRIKYERVKRNESVPAQSGDQVLEEANRQMKETLTCPSCKTRPKDCIMLKCYHLFCETCIKTMYDTRQRKCPKCNSNFGANDFHRIFI
Protein: 60S ribosomal protein L39 (C0H4H3)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- 40S ribosomal protein S8
- 60S ribosomal protein L13, putative
- 40S ribosomal protein S4
- 40S ribosomal protein S19
- 60S ribosomal protein L30e, putative
- 60S acidic ribosomal protein P0
- 40S ribosomal protein S15
- 60S ribosomal protein L27
- Small ribosomal subunit protein eS30
- 40S ribosomal protein S23, putative
Sequence:
MGSIKRFRLKQRLGKCRRQNRPVPHWYRLKKDTKIRYNTKRRHWRRTKLGL
Protein: FI07211p (Virus-induced RNA 1, isoform A) (Virus-induced RNA 1, isoform B) (Q0E8R1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Protein Vago
- Protein Turandot M
Sequence:
MKLLFGLLMTVLALSGVFTLPARNDPQDDAEVIKVPSRPQPESDFHNFRGVIDTGSGYPFLQPNPSSFNVGIFDSFDDLFRRLRTRLWPVIGRDSGEEGASPTGDSDDSSDGSGAGFPFGVRPLIPLDSKNANTTSTIKVVNGHKVEINETVYGDSNSVFKVRLVNVRPLESGEEVAQGVHTSGGDFQPALEPSTSAPPKKFEEFDEEDDDDRREPLEKQPQDNEVRDIDEPKSTTPTNTSYTTNLHTSAPIDSEFEASDISEDIVETQPEEQKNTMDQLQQMMEPLREEIRHEEDLEQEHEDKEYLERKEKKEREEFDSSDDEDGEATTPVVMSETFNDEWAEFDQDQDREHDRNEDQDHDLDFENDLNNEIDIEENFVPIDLSNDIAVNDLAAADPNFPINEDAEFIVHPAVIRTMPMFEKLSLGEPAK
Protein: Kinesin-like protein KIF16B (B1AVY7)
Organism: Mus musculus (Mouse)
Function: Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q96L93}. Early endosome membrane {ECO:0000250|UniProtKB:Q96L93}. Cytoplasm {ECO:0000250|UniProtKB:Q96L93}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q96L93}. Note=It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14. {ECO:0000250|UniProtKB:Q96L93}.
Interaction partners:
Sequence:
MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEALFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYSDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDAEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLHQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGREDASTEQDIVLHGLDLESEHCVFENAGGTVTLIPLRGSQCSVNGVQIVDATQLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSCENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETRRKETEIVQRQIRKQEESLKRRSFHIENKLKDLLAEKERFEEERLREQQGLEQQRRQEEESLFRIREELRKLQELNSHEQAEKVQIFQELDRLHQEQNAQSAKLRLEKRRLEEEEKEQVQRVAHLEEQLRKRQDTAPLLCPGEAQRAQEEKRELESIREALLQAKEMRAGGDHTCRDELERAQQYFLEFKRRQLVKLASLEKDLVQQKDLLSKEVQEEKVALEHVKCDAGGDPSFLATDDGNILGGPPDLDKIKTAETRLQSREHQLQDLLQNHLPALLEEKQRVLDALDSGVLGLDTTLCQVEKEVGEKEEQIAQYQANASQLQQLRATFEFTANVARQEEKVRRKEKEILESQEKQQREALEQAVAKLEQRRSALQRCSTLDLEIQEQRQKLGSLHTSEWSGWQASLETDGEALEMDPARLEHEIHQLKQKICEVDGVQRPHHGILEGQAVLSSLPPSGGNSHLAPLMDARISAYIEEEVQRRLHDLHRAIGDANHTPADVMKSNEELHNGTTQRKLKYERMYSRSLGTNRDDLKDPIKISIPRYVLCGQGKDEHFEFEVKISVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVVAERRTHLEKYLREFFSVMLQSETSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG
Protein: Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16) (Q9Y5Y5)
Organism: Homo sapiens (Human)
Function: Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER). May function as receptor for PEX3.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:11390669, ECO:0000269|PubMed:21768384}; Multi-pass membrane protein {ECO:0000269|PubMed:11390669}.
Interaction partners:
- Peroxisomal biogenesis factor 19
- Peroxisomal biogenesis factor 3
- Peroxisome assembly protein 12
- Peroxisomal membrane protein PEX13
- Peroxisomal membrane protein PEX14
- Peroxisome biogenesis factor 10
- Peroxisome biogenesis factor 2
- Peroxisomal targeting signal 1 receptor
- Peroxisomal ATPase PEX6
- Peroxisome assembly protein 26
Sequence:
MEKLRLLGLRYQEYVTRHPAATAQLETAVRGFSYLLAGRFADSHELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALVQLAKAVLRMLLLLWFKAGLQTSPPIVPLDRETQAQPPDGDHSPGNHEQSYVGKRSNRVVRTLQNTPSLHSRHWGAPQQREGRQQQHHEELSATPTPLGLQETIAEFLYIARPLLHLLSLGLWGQRSWKPWLLAGVVDVTSLSLLSDRKGLTRRERRELRRRTILLLYYLLRSPFYDRFSEARILFLLQLLADHVPGVGLVTRPLMDYLPTWQKIYFYSWG
Protein: Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Cell cycle regulation and translation initiation protein) (Eukaryotic translation initiation factor 3 90 kDa subunit) (eIF3 p90) (Translation initiation factor eIF3 p90 subunit) (P06103)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03001, ECO:0000269|PubMed:14562095}.
Interaction partners:
- Eukaryotic translation initiation factor 5
- Eukaryotic translation initiation factor 2 subunit gamma
- Eukaryotic translation initiation factor 3 subunit A
- Eukaryotic translation initiation factor 3 subunit J
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 2 subunit alpha
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 2 subunit beta
- Small ribosomal subunit protein RACK1
Sequence:
MKNFLPRTLKNIYELYFNNISVHSIVSRNTQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFNEEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE
Protein: Rac-like GTP-binding protein ARAC8 (GTPase protein ROP10) (Q9SU67)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a negative regulator of abscisic acid (ABA) responses.
Subcellular location: Membrane {ECO:0000269|PubMed:12368496}; Lipid-anchor {ECO:0000269|PubMed:12368496}.
Interaction partners:
- Rho GDP-dissociation inhibitor 1
- Guanine nucleotide exchange factor SPIKE 1
- KOW domain-containing protein
- Rop guanine nucleotide exchange factor 1
- Kinesin-like protein KIN-14E
- Actin binding protein family
- Cysteine/Histidine-rich C1 domain family protein
- Dol-P-Glc:Glc
- Phosphatidylinositol 4-phosphate 5-kinase 3
- At1g12070
Sequence:
MASSASKFIKCVTVGDGAVGKTCMLICYTSNKFPTDYIPTVFDNFSVNVVVEGITVNLGLWDTAGQEDYNRLRPLSYRGADVFVLAFSLISRASYENVFKKWIPELQHFAPGVPIVLVGTKMDLREDRHYLSDHPGLSPVTTSQGEELRKHIGATYYIECSSKTQQNVKAVFDAAIKVVIKPAVKQKEKKKKQKPRSGCLSNILCGKN
Protein: Eukaryotic peptide chain release factor GTP-binding subunit (EC 3.6.5.-) (ERF-3) (ERF3) (ERF2) (G1 to S phase transition protein 1) (Omnipotent suppressor protein 2) (PSI no more protein 2) (Polypeptide release factor 3) (Translation release factor 3) (P05453)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in translation termination. Stimulates the activity of ERF1. Binds guanine nucleotides. Recruited by polyadenylate-binding protein PAB1 to poly(A)-tails of mRNAs. Interaction with PAB1 is also required for regulation of normal mRNA decay through translation termination-coupled poly(A) shortening.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Eukaryotic peptide chain release factor subunit 1
- ATP-dependent helicase NAM7
- Heat shock protein 104
- Polyadenylate-binding protein, cytoplasmic and nuclear
- [PIN+] prion protein RNQ1
- Heat shock protein SSA1
- Protein SIS1
- Nonsense-mediated mRNA decay protein 2
- Mitochondrial protein import protein MAS5
- Nonsense-mediated mRNA decay protein 3
Sequence:
MSDSNQGNNQQNYQQYSQNGNQQQGNNRYQGYQAYNAQAQPAGGYYQNYQGYSGYQQGGYQQYNPDAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYKNFNYNNNLQGYQAGFQPQSQGMSLNDFQKQQKQAAPKPKKTLKLVSSSGIKLANATKKVGTKPAESDKKEEEKSAETKEPTKEPTKVEEPVKKEEKPVQTEEKTEEKSELPKVEDLKISESTHNTNNANVTSADALIKEQEEEVDDEVVNDMFGGKDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYNIKTDVVFMPVSGYSGANLKDHVDPKECPWYTGPTLLEYLDTMNHVDRHINAPFMLPIAAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPGFVLTSPKNPIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKIVKIAE