wanglab/gogpt-training-data huggingface dataset:
Protein: Frazzled, isoform B (A1Z921)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAITTNRSSRTLWNWLLSSCLIFQLIGSSLASQALSFTLEPQDAVVPEGHSVLLQCAGTASIGRGGKSKSNLPSSVSIRWRGPDGQDLVIVGDTFRTQLKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLNIKKPSDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIWGKPKPVIRWLKNGDLITPNDYMQLVDGHNLKILGLLNSDAGMFQCVGTNAAGSVHAAARLRVVPQGDSPEQDPSVPHPGGKPLDSGLQARLPSQPRDLVAQIVKSRFVTLSWVEPLQNAGDVVYYTVYYKMNNSEREQKMVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFGSGASSAPLEVSTQPEVNIAGPPRNFEGYARSHKEIYVKWEEPTVTNGEILKYRVYYSENDSGADLYHDSTALEAVLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTPSEPPNNVTLEVTSSSSITVHWEPPAEEDRNGQITGYKIRYRKFKDAPQVKSTPANIRYFELSNLDRNAEYQVKIAAMTVNGSGPFTEWNRANTLENDLDETQVPGKPIWISIHPGANNIALHWGPPQHPEIKIRNYVLGWGRGIPDENTIELKETERYHILKNLESNMDYVVSLRARNVKGDGPPIYDNIKTRDEEPVDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNKNQHVTDNRHYTVSYGITGSNRYRYHNTTDLNCMINDLRPNTQYEFAVKVVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVEAFAGEETMLMLPNLKPYTTYYFKVQARTTKGANNAPFSALVSYTTSAAVTMQEPDTIAKGIDNEKLLYIIIAATAVVLLVVLLGVLLLCRRKPQSSPEHTKKSYQKNNVGVPKPPDLWIHHDQMELKNIDKGLHTVTPVCSDGASSSGALTLPRSVVHSEYEVETPVPGHVTNSLDKRSYVPGYMTTSMNGTMERPQYPRTQYSHQNRSHMTMEAGLSQQSLTQPQSNSMAQTPEHPYGGYDANFCNAGNAAAGNGCVSTIESSKRGHPLKSFSVPGPPPTGGATPVTKHTPAVTIRPQNQSPYKKPSFSAATPNRLQGGGSVVHSTDEIQRLAPSTSTEELNQEMANLEGLMKDLSAITANEFEC
Protein: Meiotic recombination protein REC114 (P32841)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the production of double-strand breaks (DSBs) in meiotic recombination initiation; not required for mitosis. Plays a role in activation of the DSB nuclease SPO11 at recombination hotspots. Prevents accumulation of meiotic double strand break intermediates and is needed for the proper timing of the first meiotic division. Component of the MER2-MEI4-REC114 complex which seems to be required for meiotic double-strand break (DSB) formation.
Subcellular location: Nucleus {ECO:0000269|PubMed:16783010}. Chromosome {ECO:0000269|PubMed:16783010}. Note=Localizes to chromosomes.
Interaction partners:
- Meiosis-specific protein MEI4
- Recombination protein 107
- Meiotic recombination protein REC102
- Meiotic recombination protein REC104
- Meiosis-specific protein SPO11
- Antiviral protein SKI8
- Protein RED1
- Meiosis-specific protein HOP1
- Meiotic recombination 1 protein
- Meiotic recombination protein REC8
Sequence:
MYEYCSVVIKKYSKYTIPSFAPNGFQSMLEPPQIDKWQHLSANCTLQFRVLLMDSRQILINVVLNNSTLLENIRLPLGDNQDLIQFSCKSPIISCKYISEEFGPRMLRRFQMNLPNDVEFNRTVVSLKNLNFVLRTARTSIAQSTITSQVQGNNNGTKVCFTEGPKVSSYTNPNTQFQTQNMIMDFSQRYQEESERESNNRSNITLPHDSIQIAQQIWPNTDLNVVQSSQDLNTPMATQTVLGRPESLIVQPLEVSQSPPNTTNCLPNAENKKKKVDTTSDFTSRKEIALCKTGLLETIHIPKERESQMQSVTGLDATPTIIWSPGKDNTAKKNTSNKKNIDDKLTNPQKSGNTHTPDRNKEVLPNGTLNETRKEASPSEGLTIRVKNVNRNASRKISKRLIKEKLKDEEFMKWVNKVETVLNKMFEK
Protein: Papilin (Q5ZR36)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MKGFRSLGKVCIDLNECDNGAVCGPNARCVNEIGSFQCVCDAGFSTDGDCKIGQEACMDEFDVNLTEEDCNNGKQEIKYYYDADSVQCKQFFYGGCKTTSRNFFADLQTCDVICVSNQRDYLKSKGQSLSHHPVLEISSDLNNGNDLKSNHYKIDLFSSPSSPVTPNRPLSADDWPLKPITLKPALNLDFSQGKTKSTAEKHKEADDAEILVHQLTPEHNSCDLKFEPVLREECISADWAEKFFWNSEFKDCEPFWYDSSCDPRDRAGKNFFETFEDCKNKCDGVQSQYVVPITTVPDEQSKIEEVETSETPGIVDETTTTAAPEEESEENGFFFKVKPQNYLEDVLSSETEETQHYGFNPNEFLKQNSQNQKPTEITEILRILPAQTEHDEASELKKEDKIEHDILEHLKNKEPTEKVLSTPSTCDLEYDDALRNECTSADWTELYYWNAQFKECEAFWYDSSCGDQDFSKKNLFKNFDDCNNQCVKKIGEALKKMDPETTTTTSTTTTTTTAPTTTKMEEPKRSNYKQSDPLNLILNKALNPDESSELPEKFPPAHEQGFVNFAIKSEVTATTKFDRLKYMAEFRKKLLALPDNFSTTPKQSSPTSSPTTTRMRSPSTHKSTVSQATKTASSTPQSPSTTTSFDDFVEKEKKTVLETIKILDRPEDLCDEPLHPKLEEDCKNDQWEIQWFFNSDRGACKSFWYGGCEIESRNFFPDHANCRHSCAHKYATPASFSSKVYIPPGELSTPVPPRKDRLTTSLKLTYPHSEDLFPSEEHSTVVELDGNFQRTEKQERIRLFPTKTFRPRAPTPTASNIVNVSEGEKTETAPAFYSHIDRVVHDMKTGEHPGYTKPEEFVRRIESASNDYIKYDLQKPDVVTIIDKSPPTVPSRKERTERTEVTTKLPSTRSINDPCDDEYDPKWDEDCLGDTWVVRSYYDSKAEKCKAFWYGGCHTSSRNIWFDKETCRTSCAHKFPTDMPMYGGAQSSEVSAEILPSPQEENSSKETSSSSSSSSSSNTAHISPEHRFKVDLDQKFADVKREHEGREDLAYSQMVQHPVTVSADCLEVYNASLSKPCGDGKSWSNRYFYDKDTRSCRMFWSNGCFSSSKNNFDDLETCQWKCEGRHPQPAGKSCLDKFDERYLEDCRHGEFTNRFYFDHDRKKCVAFHWGGCQSKSQNFFADMTVCQDLCESPPRELTQACLQPFDTTYETSCSAEKPQQYYYFDMSSGICKMFWFGNCKGENQNIFSTLEACQWICERKRDERKPAICADKFDTKYTESCGDSQWTEKWYFDQSSGDCSSFWWDECTSSSQNIFPDEKSCTSNCKHPGFEISSKLATEESKFRCLEPVEIGSCQETYPAFYYDRASRTCRPFAYSGCGGNSNRFMTVSQCENLCFAFNSMNEAEVDCHLPMHIGYGKNEDSCLPQAGFRFYYDRNYGKCSQMWYLGCGGNANNFYSYEICQRTCSQSDVPRELERKTRASSEVCFEPPGDRGICGKNSSTNPLKRWTYGNQKCTSFTYSGCGGNRNRFATQDICENTCNGLMNSNDPRICSFSPDWGSCNQLRYVWFYNLTRGTCDQFLYGGCGGNPNRFDTFEICQKACEVTGTDPCMESLDRGSWCEAMSNRYYFNKRARQCKGFHYTGCGKSGNNFLTKEECQTKCEKRFPRAAPSKKKAKVKLPVGYSGAKPKDKTPMLRHINLNGNNQTYFKSEPQWMDYSSCYGYRYNVTGRDTILNVHYCAIRGSADCISESYRSTEGEEYCNILRPFLRGQNLYSFYFGLDSVNPMYRPKDGLSGRIQRKNETIAAVLVLKANQCHEIC
Protein: Endolytic peptidoglycan transglycosylase RlpA (EC 4.2.2.-) (Rare lipoprotein A) (P10100)
Organism: Escherichia coli (strain K12)
Function: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
Subcellular location: Cell membrane {ECO:0000255|HAMAP-Rule:MF_02071}; Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_02071, ECO:0000305|PubMed:3316191}. Note=Localizes at the septal ring. Is also associated with some other structures/complexes along the cell cylinder. {ECO:0000269|PubMed:19684127, ECO:0000269|PubMed:19880599}.
Interaction partners:
- Peptidoglycan glycosyltransferase MrdB
- Peptidoglycan D,D-transpeptidase MrdA
- Cell division protein DamX
- Membrane-bound lytic murein transglycosylase D
- Membrane-bound lytic murein transglycosylase B
- Endolytic murein transglycosylase
- Cell division protein DedD
- Soluble lytic murein transglycosylase
- Membrane-bound lytic murein transglycosylase A
- Membrane-bound lytic murein transglycosylase F
Sequence:
MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEISGADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFDPTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSNNTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILPVSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPAMVTPQAVSQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGPFASKAEASTLQQRLQTEAQLQSFITTAQ
Protein: Protein MFI (Mitochondrial fission factor interactor) (Q8NCR3)
Organism: Homo sapiens (Human)
Function: Acts as an inhibitor of mitochondrial fission. Interacts with MFF and prevents DNM1L recruitment to mitochondria, promoting a more fused mitochondrial network.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9D4W2}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9D4W2}. Note=Predominantly localizes to the cytosol, with a minor fraction at the outer mitochondrial membrane. {ECO:0000250|UniProtKB:Q9D4W2}.
Interaction partners:
Sequence:
MPWKEESEFTKQDKAARVIQQAWKSFLNVAIFQHFKSLIDLRRQGEPRQIVKYINPKEAELLDAAAGIHVRFRLGGVKFPPDIYYKIFTHRPIEDLCANSPRNYAKLPAKHTSHNKNDHLQEEDHSGWYHRIENNGWRPVSDTFWLSTDGMVVEDKKESEFHFSKLKRRQDLEKKRKLRKIEWMRQMYYSGSLEAKSTHHETLGLIHTATKGLIRAFEDGGIDSVMEWEVDEVLNWTNTLNFDEYIASWKEIATSNSSANFKGFRFNQAQKNIYNYGGDISKMQMGIPDDTYYENVYQEPNVTRLTPDSTYGL
Protein: BARP protein (Q38CW1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSITFHNLWLLLTVLCTAGIRADASKEECPDKGSYPAAEDVLVLCRVAEQLRGLPDTVSSALVNAATASSKAFEAKVQAEEAVELAESKGLNVTKAKEAAVRATLAAEAAATAASNVEINAANIAAVPWLERRQNVGWQKLAKCIDLDMDMREAARVCRRAADNVTAQSLTAALKDLEKVYTDVSTREALRKETVEFHKELASLEEHVEEAVRAQKRAEDAAAYANQTVGTNTGPVVNSVASPEGSVLLLIAGLFLGSVL
Protein: Uncharacterized protein (Q72CN2)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
Sequence:
MLNARYLDELEEYMSSGRMEDEFEYSPEERRLEILEFLERLMDVAETADATATKLIFKNSQFGTMMGLKDQK
Protein: Cellular repressor of E1A-stimulated genes, isoform C (Q8IN97)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKTFHSLLFALILALVSLDPSSGYSRRKDERIIREYKREQELNHAKIARDLVHRANWAAVGSLSTNERVKGYPMVNIISIDDSDANNRSTGRIRFLLTDLDFTGPDWQKDNKVTLLFSDEQTLRCKEGGKDPMEPTCARSMISGQVKKLTISTFANWKLAISLFWTSMEVLIK
Protein: tRNA-specific adenosine deaminase (EC 3.5.4.33) (P68398)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2). Essential for cell viability.
Interaction partners:
- Bifunctional ligase/repressor BirA
- Histidine biosynthesis bifunctional protein HisIE
- Glycerate 2-kinase
- Uracil-DNA glycosylase
- tRNA
- Adenosine deaminase
- tRNA pseudouridine synthase A
- Cytidine deaminase
- tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
- Cation-efflux pump FieF
Sequence:
MSEVEFSHEYWMRHALTLAKRAWDEREVPVGAVLVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCAGAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFFRMRRQEIKAQKKAQSSTD
Protein: Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) (mu-IRAK-2) (Q8CFA1)
Organism: Mus musculus (Mouse)
Function: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Interaction partners:
- TNF receptor-associated factor 6
- Myeloid differentiation primary response protein MyD88
- Interleukin-1 receptor-associated kinase 4
- Interleukin-1 receptor-associated kinase 3
- Interleukin-1 receptor-associated kinase 1
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
- Tumor necrosis factor receptor superfamily member 16
- NF-kappa-B essential modulator
- Toll-like receptor 4
Sequence:
MACYIYQLPSWVLDDLCRNIDTLSEWDWMQFASYVITDLTQLRKIKSMERVQGVSITRELLWWWSMRQATVQQLVDLLCHLELYRAAQIVLSWKPVPESTSPLPAFPEAVKPGAVATSRRNLKDEQEKVRPVKPRSLLDTGPIMAGAQRQRPCEMDAPCSLKTDAPDSPQSKYCSTSTSAPKQERLLGLPGDRLFWSEADVVQATEDFDQSHRISEGTFADIYQGQRNGVAFAFKKLREVAGSSPGSMDRFLQAEMQLCLRCCHANVLPLLGFCTGRQFHSLIYPYMANGSLHDRLWAQGNSDMLPWPQRASICSGLLLAVEHLHSLDIIHSNVKSANVLLDQHLNPKLAHPVAHPHPDNKKTKYTVMRTHLFQASAAYLPEHFIRVGQLTKQVDIFSCGIVLAEVLTGIPAMDKDRSPVYLKDLLLSEIPNSTSSVCSRKTSMGKAVVKEICQRHVEKRAGLLPEACEEAWATAVSVCLRRRNASVEEARVSLAGVEEQLRGQLSLPWSRVSEATGSSSNTPEETDDVDNSSLSVPSLVMMASCPGAASSPLFTGHGAAQPSTSGRQEADSSSEACTGPQTPQNATETSWKIEINEAKRRLMENIVLYKEERLDSSELFGP
Protein: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 (EC 2.1.1.-) (EC 2.1.1.367) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Protein KRYPTONITE) (Protein SET DOMAIN GROUP 33) (Suppressor of variegation 3-9 homolog protein 4) (Su(var)3-9 homolog protein 4) (Q8GZB6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression. The silencing mechanism via DNA CpNpG methylation requires the targeting of chromomethylase CMT3 to methylated histones, probably through an interaction with an HP1-like adapter. By its function, KYP is directly required for the maintenance of the DNA CpNpG and asymmetric methylation. Involved in the silencing of transposable elements.
Subcellular location: Nucleus. Chromosome. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin and at a lower level with regions of euchromatin.
Interaction partners:
- Histone H3.3
- Histone H3.1
- Histone deacetylase 6
- DNA
- DNA
- Histone H3-like centromeric protein CENH3
- Histone H3-like 5
- Histone H3-like 2
- Histone H3-like 3
- Histone H3-like 4
Sequence:
MAGKRKRANAPDQTERRSSVRVQKVRQKALDEKARLVQERVKLLSDRKSEICVDDTELHEKEEENVDGSPKRRSPPKLTAMQKGKQKLSVSLNGKDVNLEPHLKVTKCLRLFNKQYLLCVQAKLSRPDLKGVTEMIKAKAILYPRKIIGDLPGIDVGHRFFSRAEMCAVGFHNHWLNGIDYMSMEYEKEYSNYKLPLAVSIVMSGQYEDDLDNADTVTYTGQGGHNLTGNKRQIKDQLLERGNLALKHCCEYNVPVRVTRGHNCKSSYTKRVYTYDGLYKVEKFWAQKGVSGFTVYKYRLKRLEGQPELTTDQVNFVAGRIPTSTSEIEGLVCEDISGGLEFKGIPATNRVDDSPVSPTSGFTYIKSLIIEPNVIIPKSSTGCNCRGSCTDSKKCACAKLNGGNFPYVDLNDGRLIESRDVVFECGPHCGCGPKCVNRTSQKRLRFNLEVFRSAKKGWAVRSWEYIPAGSPVCEYIGVVRRTADVDTISDNEYIFEIDCQQTMQGLGGRQRRLRDVAVPMNNGVSQSSEDENAPEFCIDAGSTGNFARFINHSCEPNLFVQCVLSSHQDIRLARVVLFAADNISPMQELTYDYGYALDSVHGPDGKVKQLACYCGALNCRKRLY
Protein: Multidrug resistance protein B homolog (P9WG89)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable conserved integral membrane protein
- Transferase
- Deacetylase
- Probable periplasmic dipeptide-binding lipoprotein DppA
- KsdD-like steroid dehydrogenase Rv0785
Sequence:
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
Protein: Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Q5ZJB4)
Organism: Gallus gallus (Chicken)
Function: Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000250}.
Interaction partners:
- NF-kappa-B inhibitor alpha
- Protein kinase domain-containing protein.
- TNF receptor-associated factor
- Protein kinase domain-containing protein.
- PPM-type phosphatase domain-containing protein.
- Interferon regulatory factor 3
- NACHT domain-containing protein.
- Mitogen-activated protein kinase kinase kinase 7.
- TGF-beta activated kinase 1
- Uncharacterized protein.
Sequence:
MERGAERGPPPAPGGVALRGQPAGGCGPWEMRDRLGTGGFGNVCLYQHQDTGARVAIKSCRLELSVKNKDRWCHEIDIMKKLNHPNVVRACEVPEEMNFLVNDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIQYLHENRIIHRDLKPENIVLQDEGGKIIHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFENKSYSVTVDYWSFGTMVFECIAGFRPFLHNLQPFTWHEKIKKKDPKHIFASEEMNGEVRFSTHLPQPHSICSLIVEPMESWLQLMLNWDPEQRGGGLDPETNSPKCFLLMDHILNLKIVHILNMTSAKIVSFLLHPEESLHFLQNRIESETGISTGNQELLLETGICLDPRKPASQCVIDGVRGWDSYMVYLFDKSKTVYDGPFASRSLSECVNYIVQDSKIQLPIPQLRKVWAEAVHYVIGLKEDYSRLFQGQRAAMLSLLRYNANLIKMKNNMVSASQQLKAKLEFFHQSIRLDLERYSDQMAYGISSEKMLKAWKEMEEKASHCAQAEDIGYLDEQIMALHTEIVELQKSPYARRQGEVMESLEQRAIDLYKQLKTRPPDHAYSDSTDMVKIIVQTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKIEVALNNIKEADNSEMQMQGKRQREIWHLLKIACTQSSSRSLVSSSLEGTASTPAATWVPQSSSEYAPHPLSSMATPGDGENFVDVIEENLNYLDRFSSMLQEAREEQNNSLTNFDWSWLK
Protein: Pancreatic alpha-amylase (PA) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) (P04746)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Probable maltase-glucoamylase 2 pseudogene)
- Maltase-glucoamylase
- Sucrase-isomaltase, intestinal
- 1,4-alpha-glucan-branching enzyme
- Glycogen phosphorylase, brain form
- Glycogen phosphorylase, liver form
- Glycogen phosphorylase, muscle form
- Glycogen debranching enzyme
- Alpha-amylase 2B
- Lysosomal alpha-glucosidase
Sequence:
MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL
Protein: DnaJ heat shock protein family (Hsp40) member C7 (K7EN19)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRK
Protein: Transcriptional regulatory protein PrrA (P9WGM1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Member of the two-component regulatory system PrrB/PrrA that is involved specifically in early intracellular multiplication of Mycobacterium and is essential for its viability. Upon phosphorylation by PrrB, functions as a transcription regulator by direct binding to promoter regions of target genes to positively regulate their expression. Autoregulates its own expression.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Sensor-type histidine kinase PrrB
- Sensor-like histidine kinase SenX3
- Sensor histidine kinase component HK1
- Sensor histidine kinase TrcS
- Probable sensor histidine kinase TcrY
- Signal transduction histidine-protein kinase/phosphatase MprB
- Sensor histidine kinase MtrB
- histidine kinase
- Probable transcriptional regulatory protein
- Protein PafB
Sequence:
MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
Protein: Low-affinity methionine permease (P38734)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Very low affinity permease for methionine.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Oligo-1,6-glucosidase IMA2
- Oligo-1,6-glucosidase IMA3
- Pentafunctional AROM polypeptide
- Cystathionine beta-lyase
Sequence:
MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGVTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHKNEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC
Protein: Pre-rRNA-processing protein las1 (O42936)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for both pre-rRNA processing and heterochromatic gene silencing.
Subcellular location: Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle pole.
Interaction partners:
- Polynucleotide 5'-hydroxyl-kinase grc3
- Pre-rRNA-processing protein crb3/ipi3
- Ubiquitin-like-specific protease 1
- Probable hydroxyacylglutathione hydrolase glo2
- Probable hydroxyacylglutathione hydrolase SPCC13B11.03c
- Exosome complex component rrp40
- Pre-rRNA-processing protein ipi1
- 5'-3' exoribonuclease 2
- Brix domain-containing protein C1B9.03c
- Decapping nuclease din1
Sequence:
MDMKVVPWRLKEDFLYLMSCFYNEGQEGIPDLAALFRGVEIIQAWSTRGRIPHSVESTSQLVSSLISNDRSQKLALAVSISRFVSGLLDPIQQSQYAIPMAVLAKSIDLPTYFVELRHAITHEELPSLPVLRQAAQRALSWLYDHYWNPAATAESEDTYDYTETNELHKFEIKRKVKDLLKQWRSWRKVNVSANMFLPVEEHDYIQQFEALVQELVTTANLRLPYIPASFVDDEKDLDFAIETTNLDIVVSCFLEKRVLIPSRTMPISFFPKLKNVWLPLLQSIASKHSFFLPALFTTLWSEILEISQTVDSLVFLDLKEKEELTDKESAGCYLAKWYAYLMREAYTGQPWTSTLSVTQTDLASVLEICLQRSDPFTKIIIDELSILDKELENKFSPLFQYRSDMFDSRILDEQEFEDITLEQMKTELNKFSVRLNNIEAQADSSTMEFQGHVWYKPSVEPSPIGQIIES
Protein: Uncharacterized protein (Q95ZV9)
Organism: Caenorhabditis elegans
Interaction partners:
- G patch domain and ankyrin repeat-containing protein 1 homolog
- FH2 domain-containing protein
- WD_REPEATS_REGION domain-containing protein
- NUC153 domain-containing protein
- Gem-associated protein 2
Sequence:
MSSEWDNKIIPVIGVPLEARKLPSARIPKKPKETDGNSTETVVNSTEKPEERKEKPPKPPKQKQKQKQNLNNKFLKNLITDTGKPASMNGLFVAEEEAKLTLLEKKAMKIHIEENTLSDPQFPTYTTKHQGRIKFKCRLLWLLNKETFMKRANKPHLANIVVKQAHMEAVPPKQNVNQKKQMKNQEKNKNAKPLMDIKFDEKARSFKQRTGEDYNGGFDISSNYQGSEGSGGYQHIGNTWPNTESQWNYDPSTNGYSTFLASTPDTSTTYQPYQPSEYANFSRQLESSSSSVPVYGGATDPTQTSTSSVISFGVAVHEPISESSASAYDDPTRNHWNPQSATSDYSTVPTSGTSNVFPSYQTSEYSSFPNQTPSSSSSYQQSSQYTPMVPDLINQAINGYTTPQYNQPNQQVNQDFNTNQFSASLASLHSQPLEASEDELLRQKRLMEIEQELHMINAKKMHMQMEAEIRHREMELAKRQQLMELRERELRDRECFENGRTHAGHTGQHNYDNREYSSHHESKNPSVGGNYSSTSRSISINEDPAASHYYGQRVERKKRLGGELARRQGRVYEEVSSPGPLKRSADQSRAGSIQPAEGPSRKQRRRNNKNVQVTVNMEDISDDEEV
Protein: ATP-dependent DNA helicase homolog RECG1, chloroplastic/mitochondrial (EC 5.6.2.4) (DNA 3'-5' helicase RECG1) (F4INA9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Critical role in recombination and DNA repair.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:26462909}. Mitochondrion {ECO:0000269|PubMed:26462909}.
Interaction partners:
- Nucleolar protein
- Protein THALLO
- Something about silencing protein
- KRR1 small subunit processome component
- rRNA biogenesis protein RRP5
- Nucleolar-like protein
- DNA repair protein recA homolog 3, mitochondrial
- ATP-dependent RNA helicase DEAH13
- DNA repair protein recA homolog 1, chloroplastic
- F18K10.11 protein
Sequence:
MAAVTLSPCSMCCGSRRLRSVIVIQAQRGNWNRIRLSNFFFSKVWNISYRSKHKYSDNLLEQVEKYASARLENQSKLITKVAALMECDNVDDFIDKKSDEQVKKDLVLACKRFPSIILGDSRPVELYSNSKSYGESSSILKTPTDNSFLPTPMHGGWFDPDNLSRTLSSFCPELLQNDDSSDPREDILDDGSSFTSKTATSEVEATSDDVFAAQRFLATSIDSMPGLSKRHSNQLDSCGFHTMKKLLHHFPRTYADLQNAQVDIEDGQYLIFVGKVLSSKGVRASSSFSFLEVIVSCEVSGRDRTPEDLSHNAEDKAGKSIFLHLKKFFRGTRFTWQPFLNSIQEKHKVGDLVCISGKVKSLRAEDHFEMREYNIDVLKDEEESSHRAQGRPYPIYPSKGGLNPKFLSDVISRALRVLPANMDPIPKEITKVFGLPSLNDAYVGIHEPKTLDEADLARKRLIFDEFFYLQLARLYQMLQSLGTKIEKDVLLEKFRKPVLNSVYIEEWSTLTKSFLKALPYSLTPSQLSAVSEIIWDLKRPVPMNRLLQGDVGCGKTVVAFLACMEVIGSGYQAAFMAPTELLAIQHYEQCRDLLENMEGVSSKPTIGLLTGSTPAKQSRMIRQDLQSGAISFIIGTHSLIAEKIEYSALRIAVVDEQQRFGVIQRGKFNSKLYGTSMISKSGSSDSDDTSKADLSMAPHVLAMSATPIPRSLALALYGDISLTQITGMPLGRIPVETHIFEGNETGIKEVYSMMLEDLKSGGRVYVVYPVIDQSEQLPQLRAASAELEIVTKKFPKYNCGLLHGRMKSDDKEEALNKFRSGETQILLSTQVIEIGVDVPDASMMVVMNAERFGIAQLHQLRGRVGRGTRKSKCLLVGSSTNSLKRLNMLGKSSDGFYLANIDLLLRGPGDLLGKKQSGHLPEFPVARLEIDGNMLQEAHIAALNVLGDSHDLEKFPALKAELSMRQPLCLLGD
Protein: Uncharacterized protein (Q38CZ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- Peptidyl-prolyl cis-trans isomerase
- NADH-ubiquinone oxidoreductase complex I subunit
- Adrenodoxin reductase, putative
- NB-ARC domain-containing protein
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Uncharacterized protein
Sequence:
MRRTAFSLMIVPPESHRYAKATFHEGVHRQAPGDSTPWRDVASPLNRFKMWWLAPAAKGTMTAAWCMTIVMGAYCFSIQQDAKGTYLLNNVLLRTLHEEAMRADANQERANELQEYLKQRLEKLEAGGKAASRNMGGDAVKEGLINHELEISRERVRSDSIHQRNQQLVDELLKVRQELAVTRKKHSAALSEIDKLQKLLKACT
Protein: SEC31 homolog A, COPII coat complex component (H0YAB3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004406}.
Interaction partners:
Sequence:
XFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRV