wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein YhaP (O07523)
Organism: Bacillus subtilis (strain 168)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized ABC transporter ATP-binding protein YhaQ
Sequence:
MNKFWIMLSHTYKNKIMAKSFIISTVITVLLVLVVTNLESIISLFQGDDAKEKIAVVDETNELYPVFSKQLKAVDTDGDLDVKLSKQSEDEVTKQVKDESLDGMLIIKRDEKGTISGTYKALTISDESTYQTLQQALTQTKTAVGTAELGVSQETISSLYAPVTVGQKALKEGAKSEEELGQTVGLVYIMLFVIYFSVIMYASMIAMEVATEKSSRVMEILISSMPPIQQMFAKLLGIGLVGITQLAIIIGAGSLSLKLNQKSETASSVGGFLNLTDVSATTVIYAVIFFLLGYFLYATLAAFLGSVVSRIEDVQQTITPMTLLVVAGFMIAMFGLNAPDAGFITVTSFIPFFTPMIMFLRVGMLDIPFWQAAVGIGITLLTIVILAVIGARIYKGGVLIYGNSSAFKAIKQALRLAKN
Protein: Beta-glucuronidase (EC 3.2.1.31) (A0A0B4LGY4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRIMGLWRFLKSLILVNKEVPQTRGMLYPRESETREVRSLDGIWNFVRSDQANPTQGVRDEWYAKELSKSRPTIPMPVPASYNDITTDNLRDHVGTVWYDRKFFVPRSWSKDQRIWLRFGSVHYEAYVWINGQKVVKHEMGHLPFEAEVTDLLSYGAENRITVMCDNALIQTTVPQGRITEVPNDGGMTIVQSYTFDFFNYAGIHRSVHLYTTPRTFIEEVEVTTNLSKDATVGEVFYSVSVNGSAANEADNVLQIQANLYDKDGILVANATSDQKLGGKLQVNPVKPWWPYLMHSEPGYLYQLEIKLLATNDELLDVYRLKVGIRTLSWNSQQFLINGKPVYFRGFGRHEDSDIRGKGLDNALMVRDFNLLKWIGANAYRTSHYPYSEESMQFADEHGIMIIDECPSVDTENFSQELLGKHKSSLEQLIHRDRNHPSVVMWSIANEPRTGSVSADSYFELVANFTRSLDKTRPITAAIAVSNTQDKAGRSLDIISFNRYNAWYSNAGRLDMITQNVIDEAIAWNKRYNKPIIMSEYGADTLEGLHMQPAYVWSEEFQTEVFSRHFKAFDELRKKGWFIGEFVWNFADFKTAQSYTRVGGNKKGVFTRARQPKAAAHLLRKRYFALGRDLDQCSFPEDLFTYIADLIS
Protein: Zinc metalloproteinase nas-34 (EC 3.4.24.-) (Defective hatching protein 1) (Nematode astacin 34) (Q21059)
Organism: Caenorhabditis elegans
Function: Metalloprotease (By similarity). Required for normal hatching and migration of neuroblasts. May act by degrading eggshell proteins at hatching.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- UPF0375 protein Y45F10C.4
- UPF0375 protein Y45F10C.2
Sequence:
MVSYWPVLIVLCLLPICHAKSYFADFVNGKGPFKQADALKFMDKMTILNKLQADILGIPQPDEFSALDFEDKIESKPDEIPYLFEGDMVLTDEQMDLIIKNVRDQYWARKSSTNEFLYAIRGKRSMTSFLSERWSFPVPYYIDTSSGVNTNAVLAGVAKWEQETCARFTRLNSYSSSSRQNALRFISGNGCYSNIGKVSRFPQDVSIGWGCTSLGTVCHEIGHALGFYHEQARYDRDDYVSILTQNIQDMYLSQFTKQSASSMVDYGVGYDYGSVMHYDQAAFSSTGGNTIATRDPNFQATIGQRVAPSFADVKRINFAYCNSTCSNYLDCQNGGYINPNDCNNCKCPPGFGGQLCDVAGTNSNGCGAGDITATSSIQTISASGALTCNYVIKAPVGAKVYFQMTAATFSRYSPCTTNYLEINYGRDFSRVGARFCASYPTISLSETNTLVVIYKGVNGARFSLNYRYDPVTFSTSAPTTTSTTTTTAPITVPTVSPTTTTTRQTTTTARTSTTTTTTQAPPTTTTSTSQCASWSACSAQCGGCGTQSRRCGTYVETVYCNTNPCTGGYCCRPFFYVTSFGTGYCRRPGADTPAAPQRYVEQRKG
Protein: SWR1 complex subunit swc3 (Q10210)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}. Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Multicopy suppressor of chk1 protein 1
- Histone H2A.Z
- Actin-like protein arp6
- Probable actin-related protein 8
- SWR complex protein 2
- Helicase swr1
- Chromatin-remodeling ATPase INO80
- Chromatin-remodeling complex subunit ies6
- SWR1-complex protein 4
- RuvB-like helicase 2
Sequence:
MSLNGTFSHNNGLPSGEREESETPGGSTSIISSSFLLQPRASDSRPDALEGKYDKNVLARALKKSRDSCLNGALFEKFLPEENYKLSGGTVFSHVRYIDTATLCVGPLRFEDTKFYFVHYSNSPIEPFAKPNISYVNPQWNELDYRPDSQKLSPGKEKNTLDLKHCLLPSPEYKAPPAKKPEDYEASPGEPVEPLITDASLQRLKSRANEDPTIFNILKRISKGLGTPEQCMLLHNELIGPSTFPLPKRAKKPPRKRITLSINQQDKDEFFDSLINNKKEVRRHFDIVMEFSDAPDTKWIFPRESVLSHVFNTDKKKLEALSLLFHVYRPTEDRNVIDVKTEIKIRDFTPTLRSAIELLTSGTHADRLLSEKRRRMSNLEPKYYMQFHEQT
Protein: Frost (Q9BH93)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKVLTLILFTALVAVASGRPNGGWFGNFGSNWARRFGWGSGDDEIVQEQRWNSQNQWNPNGNGQGQWDGENGQGQSHGNNQGLGQGNGHGNNHHGHHGNNHGHGNGQGHGGQRPPPPPPTDLPELTTEDDVVSTTDVTSPAEETTLAPEVPEESTSQAPEEITTGSEEGSGSSEDTTTLAPEVPEESTTQAPEESTTDSEDDSGSEDTTQAPEETTTEEPEESTSEAPEESTSEAPEESTTEEPEESTTEALVESTSEAPEESTTEAPEESTIDSSAV
Protein: Protein KINESIN LIGHT CHAIN-RELATED 1 (O81629)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:23204523}. Cytoplasm {ECO:0000269|PubMed:23204523}. Note=Recruited by IQD1 to microtubules. {ECO:0000269|PubMed:23204523}.
Interaction partners:
- Protein IQ-DOMAIN 1
- Protein NETWORKED 3C
- Protein IQ-DOMAIN 2
- Protein IQ-DOMAIN 20
- Protein IQ-DOMAIN 5
- Protein IQ-DOMAIN 16
- Protein IQ-DOMAIN 12
- Protein IQ-DOMAIN 9
- Protein IQ-DOMAIN 25
- Calmodulin-2
Sequence:
MPAMPGLVSVKTPSDTPPLRVAVPDTQPLSNPPRTPMKKTPSSTPSRSKPSPNRSTGKKDSPTVSSSTAAVIDVDDPSLDNPDLGPFLLKLARDAIASGEGPNKALDYAIRATKSFERCCAAVAPPIPGGSDGGPVLDLAMSLHVLAAIYCSLGRFDEAVPPLERAIQVPDPTRGPDHSLAAFSGHMQLGDTLSMLGQIDRSIACYEEGLKIQIQTLGDTDPRVGETCRYLAEAYVQAMQFNKAEELCKKTLEIHRAHSEPASLEEAADRRLMAIICEAKGDYENALEHLVLASMAMIASGQESEVASIDVSIGNIYMSLCRFDEAVFSYQKALTVFKASKGETHPTVASVFVRLAELYHRTGKLRESKSYCENALRIYNKPVPGTTVEEIAGGLTEISAIYESVDEPEEALKLLQKSMKLLEDKPGQQSAIAGLEARMGVMYYTVGRYEDARNAFESAVTKLRAAGEKSAFFGVVLNQMGLACVQLFKIDEAGELFEEARGILEQERGPCDQDTLGVYSNLAATYDAMGRIEDAIEILEQVLKLREEKLGTANPDFEDEKKRLAELLKEAGRSRNYKAKSLQNLIDPNARPPKKESSAKKWPSLGFKF
Protein: Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31) (Q9EST6)
Organism: Rattus norvegicus (Rat)
Function: Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription. Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis. Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes. Also plays an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1 (By similarity). Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:10913355, ECO:0000269|PubMed:11162633}. Note=Accumulates in the nuclei at the S phase.
Interaction partners:
Sequence:
MDMKRRIHLELRNRTPAAVQELVLDNCKANDGKIEGLTDEFVNLEFLSLINVGLFSVSDLPKLPKLKKLELSENRIFGGLDRLAEELPSLTHLNLSGNNLKDISTLEPLKRLDCLKSLDLFGCEVTNRSDYRETVFRLLPQLSYLDGYDREDQEAPDSDVEVDSVEEAPDSDGEVDGVDKEEEDEEGEDEEEEEDEDGEEEEDEDEEDEDEDEDVEGEDDEDEVSGEEEEFGHDGEVDEDEEDEDEDEDEEEEESGKGEKRKRETDDEGEDD
Protein: G protein-coupled receptor 63 (cDNA FLJ78200, highly similar to Homo sapiens PSP24) (A8K1C4)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV
Protein: Dolabradiene synthase KSL4, chloroplastic (EC 4.2.3.196) (Ent-kaurene synthase-like 4) (ZmKSL4) (A0A1D6KUI6)
Organism: Zea mays (Maize)
Function: Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses. In response to fungal infection and in associtation with AN2, is involved in the production dolabradiene, a type of antifungal phytoalexin. Converts ent-copalyl disphosphate (ent-CPP) to dolabradiene.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Dolabradiene monooxygenase
Sequence:
MASLSFASSHASLFCCQQSSSAIILRPAGALLRLSRRQPSSHTISTTDQLFPRRSRMPRNVDTHAAAERNSPSTMSSLEAVDELETNGDSAVVVVREQQQQQHLLMGATDDGLPPSPYDTAWVAMVPAPGNPLVPRFPQCVDWILQNQRSDGSWGPDGGSGDHPSSPLGKDALMSTLACVLALKTWDAGEEHVRKGLSFVGNNSPSCVMTGDERDAPVGFSVIFPGMLARAIDMGLDIPMMTQANVDAFIRLRDTELNRMAATTGSKAFMSYVAEGLGDVLDWDEAAMVYQRQNGSFFNSPATTAAAAIHGNNDRALRYLDSLVNMFGSSVPTVYPRSTYSRLHMVDTLQKMGLSRSFVSEINEMLDMTYRSWLANDDEEMMLDMSTCAMAFRLLRMHGYDVSSDGLAQFSSESSFRDSVHGQANDTEALLELYKASQIQITEDELVLVDIRSWSAKLLKEQLGSDKVSRSVDAQEVQQVLKFPFYTTLDRLEHRRHIEQFKAGGFHMLKSAYRFCKEDEELVSLAVQGFHSSQALYQQELQFLTRWAKEARLHDLEFARIMPMNTFFPNAALMYAPELSEARILCTKNCMLATAVDDLFDVGGSREEMENLVRLIDMWDEHEEVGFCSERVEILFRAIYDTSKELAAKAMAVQNRSVINHVAELWADLVRAMMTEAEWSMRGHVPSSMEEYMQVAETSFALGPIVLMPLYLIGPELPEAVVRCPEYKQLFHHMNVCGRLLNDLQSYEREAKQGKINSVLLVAPRHGGSIEAAKSEVRRAIEASRRELLRMLVAEADATVPRPFRQEFWNMCKMVHLFYMEDDCYSSPKELVHAANMVVFDPLRVREL
Protein: Co-chaperonin GroES (10 kDa chaperonin) (Chaperonin-10) (Cpn10) (P61493)
Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Function: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00580}.
Interaction partners:
Sequence:
MAAEVKTVIKPLGDRVVVKRIEEEPKTKGGIVLPDTAKEKPQKGKVIAVGTGRVLENGQRVPLEVKEGDIVVFAKYGGTEIEIDGEEYVILSERDLLAVLQ
Protein: Alcohol acyl transferase 1 allele RGc (AAT1-RGc) (EC 2.3.1.-) (A0A498KE69)
Organism: Malus domestica (Apple) (Pyrus malus)
Function: Involved in the biosynthesis of volatile esters which confer ripe apple fruit flavor (By similarity). Alcohol acyl transferase that can use a wide range of alcohols as substrate to produce esters (By similarity).
Interaction partners:
Sequence:
MMPFSVLQVKRLQLELITPAKPTLQETKFLSDIDDQEGLRFQVPVIMCYKDNPSLNKNCNPVKVIREALSRALVYYYPLAGRLKEGPNRKLMVDCNGEGILFVEASADVTLEQLGDKILPPCPLLEEFLFNFPGSDGIIGCPLLLVQVTCLTCGGFILALRVNHTMCDAPGLLLFLTAIAEMARGAHAPSILPVWERELLFSRDPPRITCVHHEYEDVIDHSDGSYASSNQSNMVQRSFYFGAKEMRVLRKQIPPHVISTCSTFDLITACLSKCRTLALKINPKQAVRVSCVVNARGKHHNVRLPLRYYGNAFAFPTAVSKAEPLCKNPLGYALELVKKAKATMNEEYLRSVADLLVLRGRPQYSSTGSYLIVSDNTRAGFGDVNFGWGQPVFAGPAKALDLISFYVQHKNNTEDGILVPMCLPSSAMERFQQELERITQEPKEDICNNLRSTRIMSMM
Protein: BBSome-interacting protein 1 (BBSome-interacting protein of 10 kDa) (A8MTZ0)
Organism: Homo sapiens (Human)
Function: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for primary cilia assembly and BBSome stability. Regulates cytoplasmic microtubule stability and acetylation.
Subcellular location: Cell projection, cilium {ECO:0000269|Ref.4}. Cytoplasm {ECO:0000269|Ref.4}. Note=Localizes inside the primary cilium but not at centriolar satellites.
Interaction partners:
Sequence:
MLKAAAKRPELSGKNTISNNSDMAEVKSMFREVLPKQGPLFVEDIMTMVLCKPKLLPLKSLTLEKLEKMHQAAQNTIRQQEMAEKDQRQITH
Protein: Fasciclin-like arabinogalactan protein 12 (Q8LEE9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be a cell surface adhesion protein.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
- Fasciclin-like arabinogalactan protein 3
- Chitinase-like protein 2
- Fasciclin-like arabinogalactan protein 21
- Fasciclin-like arabinogalactan protein 14
- At4g29980
- COBRA-like protein 4
- Fasciclin-like arabinogalactan protein 19
- Putative fasciclin-like arabinogalactan protein 20
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
Sequence:
MEHSLIILLFTVLLLLTTTPGILSQPSPAVAPAPPGPTNVTKILEKAGQFTVFIRLLKSTGVANQLYGQLNNSDNGITIFAPSDSSFTGLKAGTLNSLTDEQQVELIQFHVIPSYVSSSNFQTISNPLRTQAGDSADGHFPLNVTTSGNTVNITSGVTNTTVSGNVYSDGQLAVYQVDKVLLPQQVFDPRPPAPAPAPSVSKSKKKKDDSDSSSDDSPADASFALRNVGSVCDAVSFCVMSVMLAWFYL
Protein: Sulfotransferase 1A4 (ST1A4) (EC 2.8.2.1) (Aryl sulfotransferase 1A3/1A4) (Sulfotransferase 1A3/1A4) (P0DMN0)
Organism: Homo sapiens (Human)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P0DMM9}.
Interaction partners:
Sequence:
MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL
Protein: Kallikrein-13 (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4) (Q9UKR3)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Serine protease inhibitor Kazal-type 6
- Sialic acid-binding Ig-like lectin 9
Sequence:
MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ
Protein: CDKN1A interacting zinc finger protein 1 (Q5SYW2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Protein: Extra-large guanine nucleotide-binding protein 2 (Extra-large GTP-binding protein 2) (Extra-large G-protein 2) (C6KIE6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (By similarity). Binds GTP with specificity. Plays a role in the root morphogenesis by regulation of the cell proliferation. Acts as a positive regulator in resistance to pathogen that triggers the salicylic acid (SA) pathway. Promotes the DNA binding activity of RTV1 specifically to promoter regions of FT and SOC1 in vivo leading to the activation of floral integrator genes.
Subcellular location: Nucleus {ECO:0000269|PubMed:17999646}.
Interaction partners:
- Guanine nucleotide-binding protein subunit beta
- Guanine nucleotide-binding protein subunit gamma 1
- Guanine nucleotide-binding protein subunit gamma 2
- Serine/threonine-protein kinase BIK1
- Guanine nucleotide-binding protein subunit gamma 3
- AUGMIN subunit 6
- Respiratory burst oxidase homolog protein D
- Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380
- Protein LYK5
- Chitin elicitor receptor kinase 1
Sequence:
MAAVIRKLLPFPSPNPKRDNRESDDDDETSSGYRIEYSFASEYKGPLIANVPRALPVEVDQIPTALPVSFSSLRSGISYPVAPLVMTKDTKRPPDSGIEKKNGFVDSAAGSSVVLIGRDVVSGSSSSSSSKRLDVPEEVKSPADFRLSPSSPLSASAREEDHLDDDRVSDVGPRAVRFVEPFQSSECDESSYVSDGESIAATHRAERKGKRGSCYRCQLGNRFTEKEVCIVCDAKYCFNCVRRAMGAMPEGRKCQACIGYRIDESKRASLGKCSRMLKRHLTDSELRQVMNAEITCKANQLPSRLIIVNDKPLSEDELYTLQTCPNPPKKLKPGHYWYDKVAGYWGKIGEKPSQIISPNNSIGGYISEKVSNGDTEIYINGREITKPELTMLKWAGVQCEGKPHFWVDSDGSYREEGQKHPIGNIWSKKRAKIACAVFSLPVPPASSAVEPYDVPLYEQKMLNKLLLIGSEKGGATTIYKQARSLYNVSFSLEDRERIKFIIQTNLYTYLAMVLEAHERFEKEMSNDQSSGNVGDETSAKPGNSINPRLKHFSDWVLKEKEDGNLKIFPPSSRENAQTVADLWRVPAIQATYKRLRDTLPRNAVYFLERILEISRSEYDPSDMDILQAEGLSSMEGLSCVDFSFPSTSQEESLESDYQHDTDMKYQLIRLNPRSLGENWKLLEMFEDADLVIFCVSLTDYAENIEDGEGNIVNKMLATKQLFENMVTHPSLANKRFLLVLTKFDLLEEKIEEVPLRTCEWFEDFNPLISQNQTSRHNPPMAQRAFHYIGYKFKRLYDSILEPVNMRGRSFKPKLFVCQVSLESDTVDNALRYAREILKWHVEETSMFQEMSTTSIEASSSS
Protein: Protocadherin gamma subfamily A, 7 (A0A0A6YXT1)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
MAPGQRGWGSHYRGFVLLSILLGMRWEAWAGQILYSVSEETDKGSFVGNITKDLGLQPRELAERGVRIITKGKTQLFSLNPRSGSLVTAGRIDREELCAQSPRCLVSFNILIEDKMNLYPIEVEIMDVNDNAPRFLTEEINIKIMENAAPGVRFPLKEATDSDVGKNSLQRYQLSPNHHFSLVVQSGDDGTKYPELVLEKALDREEEGLHHLVLTAYDGGDPLRSGTASIRVTVVDVNDHTPVFSLPLYQATVPENVPVGTRLLTVNAIDLDEGIYGEVTYSFWKITPELLQIFHLSSLTGELSTLKGLDYEQSSFYELEVQAQDGAGSLTKAKVLITVLDVNDNAPEVTVTSVSSPVPEDTPPGTVIALFYLQDKDSGKNGEVTCSLPENLPFKLERSIDNYYRLVTARNLDREKMSVYNITLKATDGGIPPLSTETRMSIHVSDTNDNPPTFSDSSYSIYVPENNPRGASIFSVTAQDPDSDKNAQVTYALAEDTIQGVPVSSYVSINSDTGILYALGSFDYEQFRDLQLRVTARDSGDPPLSSNVSLKLFVLDKNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGPNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQNLVVVVQDHGQPPLSATVTLTVAVANSIPDVLADLGSIRTPSEPDDSDITLYLVVAVATVSCVFLVFVTVLLALRLWRWHKSHMLQASSGGGLEDVPASHFVGLDGVQAFLQTYSHEVSLTADSRKSHIIFPQPNYVDTLISQDSCEKSDSLLTSIDFQECKGEAPSSQVS
Protein: Folate-binding protein 1 (AtFBP1) (Q94BQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Folic acid-binding protein involved in salicylic acid- (SA-) induced folate accumulation by triggering uptake and accumulation of folic acid in cells. May be implicated in the transport of the folates from the site of production (leaves) to the site of storage (fruits and seeds) and utilization (roots) (Probable).
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGRCLTKKVFLIQSPILFLHLLISLSSGAVKPDLKGVCVSKGGRFPPYELEGKPPKSVGRGSKDLTLCRVFRKKTCCSSVQTNPAFVAVRNLATYGEASQECLELFELLECSICNPNVGIQPGPPRICASFCDRVFEACKDAYFASNALKRVIGPCGVNDDIICIKASNWESNGTSFCEAAGFAVQRNDDSREKPCYGSKASLESVVESWSRDSRKETPLKTETLSCFKDLLQWVREMTTIQKISLGMSFLIAGMFLIRQSNNRNQKQRLAAIQRTARRLRGNGNGDSYSAAINRRTSSD
Protein: All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2) (Q33DR3)
Organism: Mus musculus (Mouse)
Function: Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone. Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively. The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. May play a role during cerebellar development. May regulate mitochondrial respiratory chain function.
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- 4-hydroxybenzoate polyprenyltransferase, mitochondrial
- All trans-polyprenyl-diphosphate synthase PDSS1
- Geranylgeranyl pyrophosphate synthase
- Farnesyl pyrophosphate synthase
- Dehydrodolichyl diphosphate synthase complex subunit Dhdds
- Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
- Protein farnesyltransferase subunit beta
- Dehydrodolichyl diphosphate synthase complex subunit Nus1
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Squalene synthase
Sequence:
MSLRQLLLRLSGYLGASGPPSRHWWYFRSLDSISSAGSWRGRSSRSPAHWNQVVSEAEKIVGYPASFMSLRCLLSDELSNIAMQVRKLVGTGHPLLTTARALVHDSRHNLQLRGLVVLLISKAAGPSTRNAACQNYDMVSGVYSCQRSLAEITELIHTALLVHRGIVNLSELQSSDGPLKDMQFGNKIAILSGDFLLANACNGLALLQNTKVVELLSSALMDLVHGVYQENSASTKENSIPDDIGISTWKEQTFLSHCALLAKSCQAAMELAKHDAAVQDMAFQYGKHMAMSHKINADLQPFIKDKASDSKTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGSLNYSKLRETIKAGKGVTSAIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS
Protein: Small ribosomal subunit protein bS16c (30S ribosomal protein S16, chloroplastic) (P0C474)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Uncharacterized protein
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS12cz/uS12cy
- Small ribosomal subunit protein uS2c
- 50S ribosomal protein L31
- S5 DRBM domain-containing protein
- Small ribosomal subunit protein uS9c
- Uncharacterized protein
- Small ribosomal subunit protein uS7cz/uS7cy
- Large ribosomal subunit protein bL33c
Sequence:
MLKLRLKRCGRKQRAVYRIVAIDVRSRREGRDLRKVGFYDPIKNQTCLNVPAILYFLEKGAQPTRTVSDILRKAEFFKEKERTLS
Protein: Uncharacterized protein, isoform B (Uncharacterized protein, isoform E) (Q8IR75)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform A
- Femcoat
- Kazal-like domain-containing protein
- IP19005p
- Chorion protein S18
- Mucin 12Ea
- Mucin related 11Da
- Chorion protein S16
- MIP16848p
- Uncharacterized protein
Sequence:
MFHPRSQSSSLALLLTFVLAFVGVKGDYDWYSDYSGSELDYIFADVNYDAVCPPGGYAVCATDGYSYHPFSSKCRLDSQNLKLLFAGKKELIQTDLSYCPSYPPRPYGPPAPAYGYQSKPVQNYAPVRYSSSSGQNSYAYAAASGPYGAKAVAEAPGPYPVASPSYSVSYPAAPAAYAPPPPKYPSPPSSYPVYAKPVPAYAAVYSYADTTKAPSTGSTTASATTGTTKSNRYPGYPTKYATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTAAPSNP
Protein: Lepidopteran-selective toxin (BTChl2) (ButaIT) (P81761)
Organism: Hottentotta tamulus (Eastern Indian scorpion) (Mesobuthus tamulus)
Function: Toxin with unknown function in healthy organisms. On glioma cells, interacts with chloride channels (probably ClC-3/CLCN3) and MMP2 at the surface of glioma cells. This complex is then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation (By similarity). Induces flaccid paralysis in H.virescens larvae. Is not toxic to S.falculata larvae or mice.
Subcellular location: Secreted {ECO:0000269|PubMed:11782289}.
Interaction partners:
Sequence:
MKFLYGVILIALFLTVMTATLSEARCGPCFTTDPQTQAKCSECCGRKGGVCKGPQCICGIQY
Protein: Brother of bearded A (GEO12108p1) (IP06720p) (P83262)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- BARBU
- Brother of Bearded protein A
- Bearded
- GEO09613p1
- Uncharacterized protein
- GEO04221p1
Sequence:
MFTETALVSNFNGVTEKKSLTGASTNLKKLLKTIKKVFKNSKPSKEIPIPNIIYSCNTEEEHQNWLNEQLEAMAIHLH