wanglab/gogpt-training-data huggingface dataset:
Protein: Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (Q6DLV9)
Organism: Rattus norvegicus (Rat)
Function: Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down-regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9BSM1}.
Interaction partners:
- E3 ubiquitin-protein ligase RING1
- E3 ubiquitin-protein ligase RING2
- RING1 and YY1 binding protein
- YY1 associated factor 2
- Lysine demethylase 2B
- BCL6 co-repressor
- Chromobox 2
- S-phase kinase-associated protein 1
- Chromobox protein homolog 7
- Chromobox homolog 8
Sequence:
MRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIRDFYQSRGLDRVSQPSGEEPALRGLGLPFTSFDHYYRYDEQLSLCLERLSSGKDKNKNVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQLWLSRWFGKPSPLLLQYSVKEKRR
Protein: Kinetochore protein ndc-80 (CeNDC-80) (Hec1 homolog) (Q17635)
Organism: Caenorhabditis elegans
Function: Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules.
Subcellular location: Nucleus {ECO:0000269|PubMed:14522947}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:14522947, ECO:0000269|PubMed:18765790}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24231804}. Note=Localizes to kinetochores (PubMed:14522947). The NDC80 complex localizes to microtubules. {ECO:0000269|PubMed:24231804}.
Interaction partners:
- Kinetochore protein Nuf2 homolog
- Kinetochore-binding protein 3
- Zygote defective protein 9
- Mitotic checkpoint serine/threonine-protein kinase bub-1
- Mitotic chromosome and X-chromosome-associated protein mix-1
- Kinesin-like protein
- Aurora/IPL1-related protein kinase 2
- KNL
- Outer kinetochore KNL1 complex subunit knl-1
- Calponin-homology
Sequence:
MFGDRRKTGGLNLNGRASIAITPTKRFTDYTGSTSVRKTDARPSLSQPRVSLFNTKNSSVAPRDVKSLVSLNGSKIYNFLVEYESSDAPSEQLIMKPRGKNDFIACFELIYQHLSKDYEFPRHERIEEEVSQIFKGLGYPYPLKNSYYQPMGSSHGYPHLLDALSWLIDIIRINSAVSEDTQNILFGDFMEQGKAQEKTLNYAWMTSTFRDYTNDRKAAENPSSSYWDDTKHRLRKYFEQSNEFEDMTKTAASALEMLNYECDEIEADKGNEASLKEEISRIRDDIRKAKDYLEQNLHVKQHMEKELAMVKSEQEEKISENEKVQKMVDDLKNKIELQKQIHGLTGKEVRQMNLDNNKDKEVVLEIQSELDRLSKETWKLKDEDFFKEQKSKFIHLAEQIMKILSGLNIQMNLEPLRAPTNERDLKDYWETLNKIWVPEISRQLHQRKLELETEQSRFSNKAVTAEERIQIQSETLCEAKKNEAREERIRRNERDSWKDARKHIEQRYEQLLNEKEVLLKQMKLDGSLEKEIEDETARMSATGEEHIQKRSQLEAGIRQILDLMVVEIAEIENKKIGFHVQCAGIEKAVL
Protein: Proteasome subunit beta (Q8IJT1)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU004203}. Nucleus {ECO:0000256|RuleBase:RU004203}.
Interaction partners:
- Proteasome subunit beta
- Proteasome subunit alpha type
- Proteasome subunit beta type-6, putative
- Proteasome subunit beta
- Proteasome subunit alpha type-2
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit alpha type
- Proteasome subunit beta
- Proteasome subunit alpha type-3, putative
Sequence:
MVIASDESFMNEIDNLINDVEDERIDNDELEFCVAPVNVPRNFIKYAQTQNKKLFDFHKGTTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLGKIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYDHTGFNMFYVDDSGKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFHIHKNGYDKIIEGEDVFDLHYHYTNPEQKDQYVM
Protein: Aquaporin PIP1-2 (Plasma membrane intrinsic protein 1-2) (MusaPIP1-2) (MusaPIP1;2) (P0DO53)
Organism: Musa acuminata (Banana) (Musa cavendishii)
Function: Water channel required to facilitate the transport of water across cell membrane; mercury-insensitive (By similarity). Contributes to the tolerance to multiple abiotic stresses including salt (NaCl), cold and water deprivation, by modulating cytosolic K(+)/Na(+) ratio, maintaining osmotic balance, and reducing membrane injury (e.g. oxidative injury).
Subcellular location: Cell membrane {ECO:0000269|PubMed:23745761}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MEGKEEDVRLGANKFTERQPIGTAAQSQDKDYKEPPPAPLFEPGELSSWSFYRAGIAEFVATFLFLYITILTVMGVVKSSTKCSTVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRALFYMVMQCLGAICGAGVVKGFQKGLYENNGGGANVVAPGYTKGDGLGAEIVGTFILVYTVFSATDAKRSARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKGHAWDDHWI
Protein: Protocadherin alpha-7 (PCDH-alpha-7) (Q91Y13)
Organism: Mus musculus (Mouse)
Function: Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination. Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27161523}; Single-pass type I membrane protein {ECO:0000269|PubMed:27161523}.
Interaction partners:
Sequence:
MVNLRGYNWKSQQLLLFLIIVAAWEAGSGQLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNPPMFPATQKALFILESRLLDSRFPLEGASDADVGSNALLTYRLSTNEHFSLDVPPNHEQVKPLGLVLRKPLDREEAAEIRLLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRSLYTVKLPENVPNGTLVIKVNASDLDEGVNGDVMYSFSSDVSSDIKSKFHMDTVSGEITVIGIIDFEESKAYKIPLEARDKGFPQLPGHCTILVEVVDANDNAPQLTVSSLSLPVSEDSQPGRVVTLISVFDRDSGANGQVTCSLTPHIPFKLVSTFKNYYSLVLDSALDRETIANYDVIVTARDGGSPSLWATASVSVEVADVNDNAPLFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLGPLANGVGGTMNEVVSRALVPGQVVAKVRAVDEDSGYNAWLSFELQPVAGGVRSPFRVGLYTGEISTTRALEETDALRQCLLVLVKDHGEPSLTATATVLLSLVDSGQTQKVSSKVSAGASRVDQRLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSATPTDGACAPGKPMLVCSSAVGSWSYSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Protein: AINTEGUMENTA-like 6 (F4KGW7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MMAPMTNWLTFSLSPMEMLRSSDQSQFVSYDASSAASSSPYLLDNFYGWSNQKPQEFFKEEAQLAAAASMADSTILTTFVDPQSHHSQNHIPKLEDFLGDSSSIVRYSDNSQTDTQDSSLTQIYDPRHHHNQTGFYSDHHDFKTMAGFQSAFSTNSGSEVDDSASIGRTHLAGDYLGHVVESSGPELGFHGGSTGALSLGVNVNNNTNHRNDNDNHYRGNNNGERINNNNNNDNEKTDSEKEKAVVAVETSDCSNKKIADTFGQRTSIYRGVTRHRWTGRYEAHLWDNSCRREGQARKGRQVFYSFFGMCYLIWGCILALLKINSGYDKEDKAARAYDLAALKYWNATATTNFPITNYSKEVEEMKHMTKQEFIASLRRKSSGFSRGASIYRGVTRHHQQGRWQARIGRVAGNKDLYLGTFATEEEAAEAYDIAAIKFRGINAVTNFEMNRYDVEAIMKSALPIGGAAKRLKLSLEAAASSEQKPILGHHQLHHFQQQQQQQQLQLQSSPNHSSINFALCPNSAVQSQQIIPCGIPFEAAALYHHHQQQQQHQQQQQQQNFFQHFPANAASDSTGSNNNSNVQGTMGLMAPNPAEFFLWPNQSY
Protein: Transcription factor BEE 2 (Basic helix-loop-helix protein 58) (AtbHLH58) (bHLH 58) (Protein Brassinosteroid enhanced expression 2) (Transcription factor EN 80) (bHLH transcription factor bHLH058) (Q93VJ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Positive regulator of brassinosteroid signaling.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor IBH1
- Transcription factor PAR1
- Protein transport protein SEC31 homolog B
- Protein transport protein SEC31 homolog A
- Transcription factor PRE1
- Protein transport protein SEC23 D
- Protein transport protein SEC24 A
- Transcription factor BIM1
- SEC12-like protein 2
- SEC12-like protein
Sequence:
MDLSVLDRLKWLQQQQMVSPEFLQILGSDGREELKRVESYLGNNNDELQSFRHFPEFGPDYDTTDGCISRTSSFHMEPVKNNGHSRAITLQNKRKPEGKTEKREKKKIKAEDETEPSMKGKSNMSNTETSSEIQKPDYIHVRARRGEATDRHSLAERARREKISKKMKCLQDIVPGCNKVTGKAGMLDEIINYVQSLQQQVEFLSMKLSVINPELECHIDDLSAKQFQAYFTGPPEGDSKQSIMADFRSFPLHQQGSLDYSVINSDHTTSLGAKDHTSSSWETHSQCLYNSLRTDSVSNFFSLK
Protein: PWWP domain-containing protein 6 (Q9LK91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May influence gene expression by regulating the function of the PRC2 complex and modulating H3K27me3 level.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- WD-40 repeat-containing protein MSI4
- WD-40 repeat-containing protein MSI5
- PWWP domain-containing protein 5
- PWWP domain-containing protein 3
- Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1
- PWWP domain-containing protein 1
- PWWP domain-containing protein 4
- Putative E3 ubiquitin-protein ligase RING1b
- VIN3-like protein 2
- Putative E3 ubiquitin-protein ligase RING1a
Sequence:
MGNILPTGSRVSENEGSDDNKLKEHDVKMENVKEDSEQIGDNVRSGVSSLRDNFEELENGFHVGDFVWGEEANSQQWWPGQIYDSLDASDLALKTMQKGKLLVAYFGDGSFFGWCNPLELKPFLENFKEFSKMSDSRRFLLAVEDAVREIGEHVEKFLVCDDAALVSSVALNLGIKDGVVVPDVRRKIISSLVLENPGVVLEDVKRLAMTVRFDDLLEIEVLRRKISAFYRCKGRFDLAKFDEHRYIIGLEDKEHESCQRLLRKCSGFASKKRKCGDVATTGSTTLRKKRLSEVSKIETAEKEISNGKSLSSRKRKSKRGLDENDDDGIEKREESNDSNHLEESEKKDDLATPLASICKRLNVDVSSCVKRCNGNGEAILQTGKRERKKSKYLSPEYMTDFSCRARKIKIESAESSQIQVAVRMTTPNTAIDVVKLGATPEEMLALIRAAALNAQYPKDYNSTSCDMVREFVSNYRSFNNKRNLSDVEKQPEVKQEIVDEKEKTRNEPGVELYIKTGFGSTLPSKDDLIKTYEKFGALDKERSYMFNNNSCSCVAFVNASDGEEAFNRSLEKCPFATTSTVTFKLEYPSSASSEKKEAETRKGVTEIECLKEKLEGIRALLDQSEGKITEELKMKLEDESRNLLDKVRKMII
Protein: Patatin-like phospholipase domain-containing protein 5 (EC 3.1.1.3) (GS2-like protein) (Q7Z6Z6)
Organism: Homo sapiens (Human)
Function: Has abundant triacylglycerol lipase activity.
Interaction partners:
- 1-acylglycerol-3-phosphate O-acyltransferase ABHD5
Sequence:
MGFLEEEGRWNLSFSGAGYLGAHHVGATECLRQRAPRLLQGARRIYGSSSGALNAVSIVCGKSVDFCCSHLLGMVGQLERLSLSILHPAYAPIEHVKQQLQDALPPDAHVLASQRLGISLTRWPDGRNFLVTDFATCDELIQALVCTLYFPFYCGLIPPEFRGERYIDGALSNNLPFADCPSTITVSPFHGTVDICPQSTSPNLHELNVFNFSFQISTENFFLGLICLIPPSLEVVADNCRQGYLDALRFLERRGLTKEPVLWTLVSKEPPAPADGNWDAGCDQRWKGGLSLNWKVPHVQVKDVPNFEQLSPELEAALKKACTRDPSRWARFWHSGPGQVLTYLLLPCTLPFEYIYFRSRRLVVWLPDVPADLWWMQGLLRNMALEVFSRTKAQLLGPISPPATRVLETSPLQPQIAPHREELGPTHQA
Protein: At5g08720 (Polyketide cyclase/dehydrase/lipid transporter) (Q9C5A5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL18y
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Small ribosomal subunit protein uS2y
- Small ribosomal subunit protein uS2z
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein uL18z
- Large ribosomal subunit protein eL38z/eL38y
- Small ribosomal subunit protein uS4c
Sequence:
MSVSKFPHLSHGVHTINFLNEPVFLSVLLPSPSRIRVFSSISTSGIGGGVAKCHGTRHSGAGGRGDNGLRRDSGLGFDERGERKVRCEVDVISWRERRIRGEIWVDSDSQSVWNVLTDYERLADFIPNLVWSGRIPCPHPGRIWLEQRGLQRALYWHIEARVVLDLHECLDSPNGRELHFSMVDGDFKKFEGKWSVKSGIRSVGTVLSYEVNVIPRFNFPAIFLERIIRSDLPVNLRAVARQAEKIYKDCGKPSIIEDLLGIISSQPAPSNGIEFDSLATERSVASSVGSLAHSNELNNNWGVYGKACKLDKPCTVDEVHLRRFDGLLENGGVHRCAVASITVKAPVCEVWKVLTSYESLPEIVPNLAISKILSRDNNKVRILQEGCKGLLYMVLHARAVLDLHEIREQEIRFEQVEGDFDSLEGKWIFEQLGSHHTLLKYTVESKMRKDSFLSEAIMEEVIYEDLPSNLCAIRDYIEKRGEKSSESCKLETCQVSEETCSSSRAKSVETVYNNDDGSDQTKQRRRIPGLQRDIEVLKSEILKFISEHGQEGFMPMRKQLRLHGRVDIEKAITRMGGFRRIALMMNLSLAYKHRKPKGYWDNLENLQEEIGRFQQSWGMDPSFMPSRKSFERAGRYDIARALEKWGGLHEVSRLLALNVRHPNRQLNSRKDNGNTILRTESTEADLNSTVNKNNKPYVSQDTEKWLYNLKDLDINWVQY
Protein: Probable serine/threonine-protein kinase C70.05c (EC 2.7.11.1) (O74526)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10759889}.
Interaction partners:
Sequence:
MPSDKPVFDIGSQAPERSDSESPSSRSIGSGTPAPVRKGLSKFKNSFLSRKNSSQIKSPSDYKSSAHEQRVNHTTDSMAHVPGNNSPLQTPQKSPPRQKHTAPATPIPVSASRHHKPHHSGLKNLLEKAMHPGHKSNANSPTSESPSKGFGSFINNHILHKNTSSHPSSPVNGKSSDIHKSQSYQHLKNSPPNSRTARKPVPRRANSASHNLGSTKSPNGNAKESLSRSAELPSKAKPMEINNGYRKKPSPLSPNSSIRNREGGNGSYFDGPLTASPTPSSPTGTPNSMSKSPSLSSLASTGASYRPGPSKPLVSRVRDNYANTSYESWPHSTEFDMFTYAVSGSLKLTPQGTGFDCINPANPFSPGYSGKSSMKSDDNVGSSANTAPNSPTSANSSEGNQGNGPTTYPIKPPTNISEIPRKLKSGFIPPYAKRVVPRLSAKYKLVDETKDMGSGATAVIRIVTLKNPKENEKNLRFAVKAYRRKADDETDGQYIAKLASEWLVQCRMEHPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFGSDPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTYPFRKASQNDQLYAKYCKAWREYNLICDVQNIRISKTLPYFKPVNDLPMHMQRLFFCLANPTAEQRITAQEALNLPFVQEIECCSVDDCTCTHDAPEECLEWANPPVQKLSTPHNHL
Protein: Protein RESPONSE TO LOW SULFUR 4 (Q8L8S2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for flower development in short-day conditions.
Interaction partners:
- Proteinase inhibitor I25, cystatin, conserved region
- Hydrolase-like protein family
- Nonsense-mediated mRNA decay-like protein
- tRNA-specific adenosine deaminase TAD3
Sequence:
MGKGGNYVMVAASEVEELRQKNGEMEKAVEEMRKEMLQLWRRTQVAEEAEEHLCSQLAELEAESLDQARDYHTRIIFLTNQLSRFSSDSASP
Protein: Hexosyltransferase (EC 2.4.1.-) (Q57VH7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}.
Interaction partners:
- Dolichol-phosphate mannosyltransferase subunit 1
Sequence:
MAIKSRGVKVVIIVFIAVYVLTITNVLISLHRFHQNSQKEVVKIQRDEPLPDFEYTEDDKMALEFVTPHIIKKWRNHNYLVALGIPSPDNEERRRRRQLQRDTCWKYPGVATVENNFEGDMLVAYVLARHPQFDYKYSPELKDEANKWRDVITLPINEGRVTTKKKLGEVAHWGIDAEIGMSRKIYLWFELGARLLPKTSYFSKGDDDAFFHSPQYIIDLRTLPRRGVYWAFHWRINPVRPFIFGRGLLYTMSRDVVNKFVTYEPVRRLVHVPFSFDRLLEFKQSIMEYEDAMVGHALSYQNPEELLFVNESCCRFIILNGNECKPPKNNNFVVVHGIQEEEYAIMMERFKNYTTPVPVQFIPSKYGWMANCTLPPDPQRRRDAEWTA
Protein: Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) (Q6Q1S2)
Organism: Human coronavirus NL63 (HCoV-NL63)
Function: S1 region attaches the virion to the cell membrane by interacting with host ACE2, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Subcellular location: Virion membrane {ECO:0000255|HAMAP-Rule:MF_04200}; Single-pass type I membrane protein {ECO:0000255|HAMAP-Rule:MF_04200}. Host endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000255|HAMAP-Rule:MF_04200}; Single-pass type I membrane protein {ECO:0000255|HAMAP-Rule:MF_04200}. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. {ECO:0000255|HAMAP-Rule:MF_04200}.
Interaction partners:
Sequence:
MKLFLILLVLPLASCFFTCNSNANLSMLQLGVPDNSSTIVTGLLPTHWFCANQSTSVYSANGFFYIDVGNHRSAFALHTGYYDANQYYIYVTNEIGLNASVTLKICKFSRNTTFDFLSNASSSFDCIVNLLFTEQLGAPLGITISGETVRLHLYNVTRTFYVPAAYKLTKLSVKCYFNYSCVFSVVNATVTVNVTTHNGRVVNYTVCDDCNGYTDNIFSVQQDGRIPNGFPFNNWFLLTNGSTLVDGVSRLYQPLRLTCLWPVPGLKSSTGFVYFNATGSDVNCNGYQHNSVVDVMRYNLNFSANSLDNLKSGVIVFKTLQYDVLFYCSNSSSGVLDTTIPFGPSSQPYYCFINSTINTTHVSTFVGILPPTVREIVVARTGQFYINGFKYFDLGFIEAVNFNVTTASATDFWTVAFATFVDVLVNVSATNIQNLLYCDSPFEKLQCEHLQFGLQDGFYSANFLDDNVLPETYVALPIYYQHTDINFTATASFGGSCYVCKPHQVNISLNGNTSVCVRTSHFSIRYIYNRVKSGSPGDSSWHIYLKSGTCPFSFSKLNNFQKFKTICFSTVEVPGSCNFPLEATWHYTSYTIVGALYVTWSEGNSITGVPYPVSGIREFSNLVLNNCTKYNIYDYVGTGIIRSSNQSLAGGITYVSNSGNLLGFKNVSTGNIFIVTPCNQPDQVAVYQQSIIGAMTAVNESRYGLQNLLQLPNFYYVSNGGNNCTTAVMTYSNFGICADGSLIPVRPRNSSDNGISAIITANLSIPSNWTTSVQVEYLQITSTPIVVDCATYVCNGNPRCKNLLKQYTSACKTIEDALRLSAHLETNDVSSMLTFDSNAFSLANVTSFGDYNLSSVLPQRNIRSSRIAGRSALEDLLFSKVVTSGLGTVDVDYKSCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGMVLGGLTSAAAIPFSLALQARLNYVALQTDVLQENQKILAASFNKAINNIVASFSSVNDAITQTAEAIHTVTIALNKIQDVVNQQGSALNHLTSQLRHNFQAISNSIQAIYDRLDSIQADQQVDRLITGRLAALNAFVSQVLNKYTEVRGSRRLAQQKINECVKSQSNRYGFCGNGTHIFSIVNSAPDGLLFLHTVLLPTDYKNVKAWSGICVDGIYGYVLRQPNLVLYSDNGVFRVTSRVMFQPRLPVLSDFVQIYNCNVTFVNISRVELHTVIPDYVDVNKTLQEFAQNLPKYVKPNFDLTPFNLTYLNLSSELKQLEAKTASLFQTTVELQGLIDQINSTYVDLKLLNRFENYIKWPWWVWLIISVVFVVLLSLLVFCCLSTGCCGCCNCLTSSMRGCCDCGSTKLPYYEFEKVHVQ
Protein: Acyl-CoA-binding domain-containing protein 5 (B7Z2R7)
Organism: Homo sapiens (Human)
Subcellular location: Peroxisome membrane {ECO:0000256|ARBA:ARBA00004549}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004549}.
Interaction partners:
Sequence:
MFQFHAGSWESWCCCCLIPADRPWDRGQHWQLEMADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVLQRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYLYYQRRRRKLN
Protein: Cytochrome P450 2A3 (EC 1.14.14.1) (CYPIIA3) (Coumarin 7-hydroxylase) (P20812)
Organism: Rattus norvegicus (Rat)
Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Interaction partners:
Sequence:
MLASGLLLVASVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNYLQLNTEKMYSSLMKISQRYGPVFTIHLGPRRVVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSSGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIESFRKTNGALIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEQNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQAKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFREFLLPKGTEVFPMLGSVLKDPKFFSNPNDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFCFKSPQAPQDIDVSPRLVGFATIPPNYTMSFLSR
Protein: TSET complex member tstD (Protein TSPOON) (C0HLF1)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cell membrane {ECO:0000269|PubMed:24867644}; Peripheral membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:24867644}.
Interaction partners:
- WD40 repeat-containing protein DDB_G0271002
- Coatomer subunit delta
- Coatomer subunit gamma
- Coatomer subunit epsilon
- Coatomer subunit beta'
Sequence:
MINSLLITNNNGNIVFSKYYSNINDEKQSEYEKLLYQFTKDEWVNSKNEKHLVTEFSGYITVFTNVGDLMLFLCGSEEMDELALSDVFFPIIESLKDICKKKGVTEQNFIEQIPKFILYLDEIIQRGHLDQVQLESIQNYSSLKHDQPIKKDNV
Protein: Nitrogen-responsive transcriptional regulator (A0A1D8PNX9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein URE2
- Ammonium transporter
- Serine/threonine-protein kinase TOR
Sequence:
MTTSNSQSKQFETVPSIVDLLYSAKKLLNLQPRIDNLHLRRSNSRTQLVMQSQALSMNNRNTASNGKDDNQSFSISPVNNQALGATHDKVLDLLSPLSIDDLKNNTITTTTTTTTSYHQNKSNQRLNGNVNTNPTHNTGNNSDTRSTLFKPRSPHSENTSPKNILSSSSSSATTTVVAVPKVNNLNHNTTTNNDGGNSEFKSSNSSLPSKKVTKCYNCNTTATPLWRRDAEGNTLCNACGLFLKLHGTCRPLSLKSDVIKKRNSRKTSTSSKVGTSTNQFINTSVRGNDVRMKQTPIAIAATSSSTSLSGSGGVSGANSLPSSQRFKNVLILPKPPSGTNLTGSARTKSIPIPANNAPSPDGPFSPSLKRKKSEVDVGPRTPTSLSASASASFSMRNRVPSSSSLTGTSFTNSIKRNNSFSNRKSSLTSLMQRKNTLGTTPTTTNSLTSSNINILNQRFPQPTYFENFGNNNSGPQSPAISRHNSTTTLMNSNQVILENVNTPGSYNSTNSFPSYVPHETPNSIPETPLNVNDLLPSSFNRRSSQMSTRQERVLEEYRASKPPAMPHKGIDDEMMIMDALNDFPGLEAIDMGNPNGMSTDNYNNEYNDLFRKFTSLENDPFVDQTANSNQNNNYGFQQIPTGNNFYKVGNNGNIGSANKNNSSNVSNNSGDYKDLDWLKFDI
Protein: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (HepA-related protein) (Sucrose nonfermenting protein 2-like 1) (H7BYI2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
QLLSYELGQGHAQASPEIRFTPFANPTHKPLAKPKSSQETPAHSSGQPPRDAKLEAKTAKASPSGQNISYIHSSSESVTPRTEGRLQQKSGSSVQKGVNSQKGKCVRNGDRFQVLIGYNAELIAVFKTLPSKNYDPDTKTWNFSMNDYSALMKAAQSLPTVNLQPLEWAYGSSESPSTSSEGQAGLPSAPSLSFVKGRCMLISRAYFEADISYSQDLIALFKQMDSRRYDVKTRKWSFLLEEHSKLIAKVRCLPQVQLDPLPTTLTLAFASQLKKTSLSLTPDVPEADLSEVDPKLVSNLMPFQRAGVNFAIAKGGRLLLADDMGLGKTIQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPDCINVVVTGKDRLTAGLINIVSFDLLSKLEKQLKTPFKVVIIVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRMPWGWDYSGSSNLGELKLLLEEAVMLRRLKSDVLSQLPAKQRKIVVIAPGRINARTRAALDAAAKEMTTKDKTKQQQKDALILFFNRTAEAKIPSVIEYILDLLESGREKFLVFAHHKVVLDAITQELERKHVQHIRIDGSTSSAEREDLCQQFQLSERHAVAVLSITAANMGLTFSSADLVVFAELFWNPGVLIQAEDRVHRIGQTSSVGIHYLVAKGTADDYLWPLIQEKIKVLAEAGLSETNFSEMTESTDYLYKDPKQQKIYDLFQKSFEKEGSDMELLEAAESFDPGSASGTSGSSSQNMGDTLDESSLTASPQKKRRFEFFDNWDSFTSPL
Protein: Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB) (P16989)
Organism: Homo sapiens (Human)
Function: Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Tight junction protein 1
- Decorin
- Cyclin-dependent kinase 4
- G1/S-specific cyclin-D1
- Symplekin
- Y-box-binding protein 1
- Ras-related protein Ral-A
- Ras-related protein Ral-B
- Eukaryotic initiation factor 4A-III
- Tight junction protein 2
Sequence:
MSEAGEATTTTTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPNRIQAGEIGEMKDGVPEGAQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENPAPPTQQSSAE
Protein: Rifin (Q8I3E1)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKLNYTKILLFFFPLNILVTSYHAYNKNKPYLKTRHTPRYTSRVLSECDIRSSIYDNDAEMKSVKGTFDRQTSQRFEEYQERIKDKRQKRKEERDKNIQEIIEKDKMDKSLAEKVETGCLKCGCGLGGVAAGVGIIGGIAINIWKPTALDAAIEAAIAKSAAKGATAFKSAVIEGIEKEFGVSILRVHRFESFIDVENYMKVSVISEKVYSHYNTTCIPSGSVHLPSVSDPICTLVSKKLPHASQGSSRTVIESTVKTVVSEAEVSAGMAVKKATDEAIQRSIGVVDAKYAICQTAIIASVVAILIIVLVMIIIYLVLRYRRKKKMNKKLQYTKLLNQ