wanglab/gogpt-training-data huggingface dataset:
Protein: Trk system potassium uptake protein TrkG (P23849)
Organism: Escherichia coli (strain K12)
Function: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA. Requires TrkE (sapD) for maximal transport activity, low activity is seen in its absence; no further stimulation is seen with SapF. Transport in the absence of SapD is dependent on a high membrane potential and a high cytoplasmic ATP concentration, suggesting this protein may be able to interact with other ATP-binding proteins. Can transport potassium and rubidium.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:2022616}; Multi-pass membrane protein {ECO:0000269|PubMed:2022616}.
Interaction partners:
- Trk system potassium uptake protein TrkA
- Low affinity potassium transport system protein Kup
- Voltage-gated potassium channel Kch
- Putrescine export system ATP-binding protein SapD
- Glutathione-regulated potassium-efflux system protein KefC
Sequence:
MNTSHVRVVTHMCGFLVWLYSLSMLPPMVVALFYKEKSLFVFFITFVIFFCIGGGAWYTTKKSGIQLRTRDGFIIIVMFWILFSVISAFPLWIDSELNLTFIDALFEGVSGITTTGATVIDDVSSLPRAYLYYRSQLNFIGGLGVIVLAVAVLPLLGIGGAKLYQSEMPGPFKDDKLTPRLADTSRTLWITYSLLGIACIVCYRLAGMPLFDAICHGISTVSLGGFSTHSESIGYFNNYLVELVAGSFSLLSAFNFTLWYIVISRKTIKPLIRDIELRFFLLIALGVIIVTSFQVWHIGMYDLHGSFIHSFFLASSMLTDNGLATQDYASWPTHTIVFLLLSSFFGGCIGSTCGGIKSLRFLILFKQSKHEINQLSHPRALLSVNVGGKIVTDRVMRSVWSFFFLYTLFTVFFILVLNGMGYDFLTSFATVAACINNMGLGFGATASSFGVLNDIAKCLMCIAMILGRLEIYPVIILFSGFFWRS
Protein: Armadillo-domain containing rhoptry protein (C0H4A5)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MGNNCCAGRDLLYKNKLQEFGIEGSKTIRKLLSFTSNDILRFDKAYDENDVQEFVNLCSSTCEIEKLEDRMHPWAADPKTIGALSATQLAILASKENEPHYKDAIREANGIAVFINLLKSHELDRVHAAVVALSFLSVDNVKNCICMFESGALPYLISGMKSNIDGMKAACAQTCRNIFVLDKKYKKEFLKLGGITQLVNLLELPSNYDDSQPLYTQLEAIYHLEDFILNDGDEIPEFLEAVKNSNSIKNLKTLQQCPEQDLAEASNVLLLRLTD
Protein: Formate dehydrogenase 2 subunit alpha (cytochrome c-553) (FDH2 subunit alpha (cytochrome c-553)) (EC 1.17.2.3) (Formate dehydrogenase large subunit (cytochrome c-553)) (Q727P3)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Alpha chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The alpha subunit of formate dehydrogenase forms the active site.
Subcellular location: Periplasm {ECO:0000269|PubMed:8566699}.
Interaction partners:
- Formate dehydrogenase 2 subunit beta
- Formate dehydrogenase, beta subunit, putative
- Formate dehydrogenase, beta subunit, putative
- Pyridine nucleotide-disulfide oxidoreductase
- Cytochrome c3))
- Formate dehydrogenase formation protein FdhE, putative
- Iron-sulfur protein CooF
- Formate dehydrogenase, alpha subunit, selenocysteine-containing
- Carbon monoxide dehydrogenase
- Formamidase
Sequence:
MKTTRRSFLKLVGVSVVGLSLGQLGFDLEDAQAYAVKLKIEGAKEVGTVCPFCSVCCQVIAYVRNGKLVSTEGDPDFPVNEGALCAKGAALFSMYTNPHRLTKPLYRAPHSDKWVEKDWDWTLNQIARRVKDARDKDMILKNDKGQTVNRLESIFMMGTSHASNEECAVIHQAMRGLGVVHMDHQARVUHSPTVAALAESFGRGAMTNHWIDIKNTDAVLIIGSNAAEHHPVAFKWIMRARDNGAVLMHVDPKFSRTSARCDFHVPLRSGTDIAFLGGMVNHIIAKDLYFKDYVANYTNAAFVVGKDYAFEDGIFSGYDPKTRTYDRSKWEFEKGPDGGPVMDPTLKNERCVFNLMKKHYERYTLKNVSDVTGVSEENLLRVYDAFCATGRPDKAGTILYALGWTQHTVGVQNIRTSTLIQLLLGNIGVAGGGINALRGEPNVQGSTDHALLYHILPGYNAMPVAQWQTLADYNKANTPVTTLKNSANWWSNRPKYVASLLKGWFGDAATPENDFCYEYLPKLEKGEDYSYMYVMDRMYHGKLKGGFIFGVNPMNSFPNTNKMRAALDKLDWLVCSELHNSETTDNWKRPGVDPKACKTEVFLLPSAHRVEKAGTISNSGRWLQWFDKAVEPGQARNFADIFVPLVNKIRALYKAEGGTLPDPVLKLHWTDKFDPEEWTRRINGFFWADTKVGDKEYKRGQLVPAFGQLKDDGSTSSLNWLYTGSYTEEDGNKSKRRDARQTPMQANIGLFPNWSWCWPVNRRILYNRASVDVNGKPWNPKKAVIEWDGAKWVGDVPDGPWPPMADKEKGKLPFIMNKDGFAQFYGTGRMDGPFPEHYEPAETPLDSHPFSKQLSSPVYKFHTSDMDQIAKAADPKYPIVLTTYSLTEHWCGGGETRNVPNLLETEPQLYIEMSPELAEEKGIKNGDGVIVESIRGRAEAIAMVTVRIRPFTVMGKTVHLVGMPFAYGWTTPKCGDSTNRLTVGAYDPNTTIPESKACLVNVRKADKLTEIA
Protein: Uncharacterized protein C9orf57 (Q5W0N0)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein C9orf85
Sequence:
MKKIEISGTCLSFHLLFGLEIRMRRIVFAGVILFRLLGVILFRLLGVILFGRLGDLGTCQTKPGQYWKEEVHIQDVGGLICRACNLSLPFHGCLLDLGTCQAEPGQYCKEEVHIQGGIQWYSVKGCTKNTSECFKSTLVKRILQLHELVTTHCCNHSLCNF
Protein: Candida glabrata strain CBS138 chromosome M complete sequence (B4UN63)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
Sequence:
MPSKITFESLTALGQDTLGTLTFDEKHHLIDTSGIGEKINKSFVADAVRKSNDELGKLGYQVYEDSKVVGHAFKDGAGKTTVYFHDKKDEKK
Protein: Uncharacterized protein (Q4GYR6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- PBP1-interacting protein XAC1
Sequence:
MSAWASGDTLERLKLKPETAPSNRGNGRQASADATSSTSVKATSNADAEGVVQASMAATIASTNKNKNKKALEGKVSKKNAPKNTAHTADEKQPPTQEQTASSSGGAKRNEPKKGASDSRDCPVTLPSDVAELVVNAFTFIGTVQALRAGTSTDGRESMLSAAVRAPEFVPQRRDYAVQNATSGSDTQHVGELASNAYPMHHHHHHHHYQLHQQQKQPQHTPLVSTSRVQQQEQPPWAPYYNDQQHRQHHSVHHHRHQQQQQQLAYGQPDCTTGKMYHDAYSPVDYDMNLCAAPPYSRMYSGYPGMCMGANMLPNMSGYGGLALRRPLPYFPQQQNQVTAYKSTHVGQQQPWMRNDSGPSNARKGSGAGQWYPGGQAGFNDALSVWNQQRNAGNWARQAEQSGPAGAHTSSAP
Protein: CDC42 small effector protein 1 (CDC42-binding protein SCIP1) (Small effector of CDC42 protein 1) (Q9NRR8)
Organism: Homo sapiens (Human)
Function: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
Subcellular location: Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Recruited to the activated TCR prior actin polymerization.
Interaction partners:
- Cell division control protein 42 homolog
Sequence:
MSEFWHKLGCCVVEKPQPKKKRRRIDRTMIGEPMNFVHLTHIGSGEMGAGDGLAMTGAVQEQMRSKGNRDRPWSNSRGL
Protein: DNA-directed RNA polymerase subunit Rpo2 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit B) (Q980R1)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (Probable). This subunit is involved in DNA promoter recognition (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:B8YB55}.
Interaction partners:
- DNA-directed RNA polymerase subunit Rpo1N
- DNA-directed RNA polymerase subunit Rpo1C
- DNA-directed RNA polymerase, subunit B''
- DNA-directed RNA polymerase subunit Rpo5
- DNA-directed RNA polymerase subunit Rpo3
- DNA-directed RNA polymerase subunit Rpo6
- DNA-directed RNA polymerase subunit Rpo10
- Large ribosomal subunit protein uL16
- Small ribosomal subunit protein uS12
- Large ribosomal subunit protein uL2
Sequence:
MASNLTIDERWRVIEAYFKSKGLVRQHLDSYNDFVRNKLQEIIDEQGEIPTEIPGLKVRLGKIRIGKPRVRESDRGEREISPMEARLRNLTYAAPLWLTMIPVENNIEAEPEEVYIGDLPIMLKSAIDPISQYTLDKLIEIGEDPKDPGGYFIVNGSERVIVTQEDLAPNRVLVDTGKTGSNITHTAKIISSTAGYRVPVTIERLKDGTFHVSFPAVPGKIPFVILMRALGILTDRDIVYAVSLDPEVQNELFPSLEQASSIANVDDALDFIGSRVAIGQKRENRIEKAQQIIDKYFLPHLGTSAEDRKKKAYYLAYAISKVIELYLGRREPDDKDHYANKRLRLAGDLFASLFRVAFKAFVKDLTYQLEKSKVRGRKLALKALVRPDIVTERIRHALATGNWVGGRTGVSQLLDRTNWLSMLSHLRRVISSLARGQPNFEARDLHGTQWGRMCPFETPEGPNSGLVKNLALMAQIAVGINERIVEKTLYEMGVVPVEEVIRRVTEGGEDQNEYLKWSKVILNGRLIGYYQDGGELANKIRERRRKGEISDEVNVGHIVTDFINEVHVNCDSGRVRRPLIIVSNGNPLVTIEDIEKLESGAITFDDLVRQGKIEYLDAEEEENAYVALEPNDLTPDHTHLEIWSPAILGITASIIPYPEHNQSPRNTYQSAMAKQALGLYAANYQLRTDTRAHLLHYPQRPLVQTRALDIIGYTNRPAGNNAILAVMSFTGYNMEDSIIMNRSSVERGMYRSTFFRLYSTEEVKYPGGQEDKIVMPEAGVRGYKGKEYYRLLEDNGVVSPEVEVKGGDVLIGKVSPPRFLQEFKELSPEQAKRDTSIVTRHGEMGIVDLVLITETAEGNKLVKVRVRDLRIPTIGDKFASRHGQKGVIGMLIPQVDMPYTVKGVVPDIILNPHALPSRMTLGQIMEGIAGKYAALSGNIVDATPFYKTPIEQLQNEILRYGYLPDATEVVYDGRTGQKIKSRIYFGVVYYQKLHHMVADKLHARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGFGTAMLLKDRLLDNSDRTMIYVCDQCGYIGWYDKNKNKYVCPIHGDKSNLFPVTVSYAFKLLIQELMSMIISPRLVLEDKVGLSGG
Protein: Puromycin-sensitive aminopeptidase-like protein (EC 3.4.11.-) (A6NEC2)
Organism: Homo sapiens (Human)
Function: Aminopeptidase with broad substrate specificity to several peptides.
Interaction partners:
Sequence:
MWLAAAAPSLARRLLFLGPPPPPLLLLVFSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINCSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDERAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVTSTYLVAFVVGEYDFVETRSKDGVCVCVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWDLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLRLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAAAGNL
Protein: Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein) (Q9H3P2)
Organism: Homo sapiens (Human)
Function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:11150502}.
Interaction partners:
- Negative elongation factor E
- Transcription elongation factor SPT5
- Negative elongation factor C/D
- Negative elongation factor B
- Transcription elongation factor SPT4
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase II subunit RPB9
Sequence:
MASMRESDTGLWLHNKLGATDELWAPPSIASLLTAAVIDNIRLCFHGLSSAVKLKLLLGTLHLPRRTVDEMKGALMEIIQLASLDSDPWVLMVADILKSFPDTGSLNLELEEQNPNVQDILGELREKVGECEASAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLQKSTETAQQLKRSAGVPFHAKGRGLLRKMDTTTPLKGIPKQAPFRSPTAPSVFSPTGNRTPIPPSRTLLRKERGVKLLDISELDMVGAGREAKRRRKTLDAEVVEKPAKEETVVENATPDYAAGLVSTQKLGSLNNEPALPSTSYLPSTPSVVPASSYIPSSETPPAPSSREASRPPEEPSAPSPTLPAQFKQRAPMYNSGLSPATPTPAAPTSPLTPTTPPAVAPTTQTPPVAMVAPQTQAPAQQQPKKNLSLTREQMFAAQEMFKTANKVTRPEKALILGFMAGSRENPCQEQGDVIQIKLSEHTEDLPKADGQGSTTMLVDTVFEMNYATGQWTRFKKYKPMTNVS
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (F5H7T0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASNQNSPIRTFGLNLSSDSSALGAVASDSEQSKTEEERESRSLFPGSLKPKLGKRDYLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAESISSLYGKPQLDDVSQVLLVMDTRTEQTFILKGLRKSSEYSRNRKTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGKLWSYISKFLNRSPEESFDIKEVKKPTLAKVHLQQPTSSPQDSSSFESRGSDGGSMLKALPLKSSLTPSSQDDSNQEDDGQDSSPKWPDSGSSSEEECTTSYLTLCNEYGQEKIEPGSLNEEPFMKTEGNGVDTKAIKSFPAHLAADSDSPSTQLRAHELKFFPNDDPEAVSSPRTSDSLSRSKNSPMEFFRIDSKDSASELLGLDFGEKLYSLKSEPLKPFFTLPDGDSASRSFNTSESKVEFKAQDTISRGSDDSVPVISFKDAAFDDVSGTDEGRPDLLVNLPGELESTREAAAMGPTKFTQTNIGIIENKLLEAPDVLCLRLSTEQCQAHEEKGIEELSDPSGPKSYSITEKHYAQEDPRMLFVAAVDHSSSGDMSLLPSSDPKFQGLGVVESAVTANNTEESLFRICSPLSGANEYIASTDTLKTEEVLLFTDQTDDLAKEEPTSLFQRDSETKGESGLVLEGDKEIHQIFEDLDKKLALASRFYIPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPLERLGAGVAGVEDIKSHPFFTPVDWAELMR
Protein: Uncharacterized protein (Q383L7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEDEPTQILLTREQLERSVERLSKPHSREVNLKPLCKSVRLPQEARERSIKHLYNDSMEHKERRLREIEQSLNAEIEKYHAGKPKLDSADTEGLVSRLYNESIQRKNDNLRQLFEHQVSLSRPKEKKLKKAEQQEFVTRLYQGGMEHNRKKHIALFEEHVLAREPKMAQRSPEDLEIACSKLTSGKSVTDD
Protein: Cytoglobin (Nitric oxygen dioxygenase) (EC 1.14.12.-) (Nitrite reductase CYGB) (EC 1.7.-.-) (Pseudoperoxidase CYGB) (EC 1.11.1.-) (Superoxide dismutase CYGB) (EC 1.15.1.1) (Q9CX80)
Organism: Mus musculus (Mouse)
Function: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14660570, ECO:0000269|PubMed:15663964, ECO:0000269|PubMed:34930834}. Nucleus {ECO:0000269|PubMed:14660570, ECO:0000269|PubMed:15663964}. Note=Nuclear localization is observed in neurons. {ECO:0000269|PubMed:14660570}.
Interaction partners:
- Neuroglobin
- Androglobin
Sequence:
MEKVPGDMEIERRERSEELSEAERKAVQATWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFRHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVEPMYFKILSGVILEVIAEEFANDFPVETQKAWAKLRGLIYSHVTAAYKEVGWVQQVPNTTTPPATLPSSGP
Protein: Pre-protein-C8 [Cleaved into: Immunity protein HalI; Halocin-C8 (HalC8)] (P83716)
Organism: Halobacterium sp. (strain AS7092)
Function: Has antibacterial activity against a wide variety of haloarchaeons. Causes cell lysis and death, possibly by disrupting the cell wall.
Subcellular location: [Halocin-C8]: Secreted. Note=Secreted (PubMed:12811620, PubMed:15978083). {ECO:0000269|PubMed:12811620, ECO:0000269|PubMed:15978083}.; SUBCELLULAR LOCATION: [Immunity protein HalI]: Cell membrane. Note=Exclusively localizes to the cell membrane. {ECO:0000269|PubMed:15978083}.
Interaction partners:
Sequence:
MKEDNNTSEESGRINRRNVLKTVGAAGLFAAGSTGMAAAADSLSQAEEPKLLTGTEKRTLARELAKTPAFRELAQRARADGAQIRSDADSIVAGYARGEDFAREVVQYDLENLTDAAEASIVIGRNPETGEIEVANLDYYYETDDGVLDEVHRFEPTNASETDGVQSAATSDGATVIAVDTDAIREAQNSEIDVDESSPSNAAPTPADIDITGCSACKYAAGQVCTIGCSAAGGFICGLLGITIPVAGLSCLGFVEIVCTVADEYSGCGDAVAKEACNRAGLC
Protein: Palmitoyltransferase ZDHHC16A (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 16A) (DHHC-16A) (B8A4F0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Palmitoyl acyltransferase that mediates palmitoylation of proteins and is required during embryonic heart development. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q969W1}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9ESG8}.
Interaction partners:
- Palmitoyltransferase
- palmitoyl-protein hydrolase
Sequence:
MHPCSSVLHLLLRCMRGCCRHTRSRVPRRLRRHVSYIRLIFKSLYFNSLTNSDVVTDSILEPVFWMVEVVTRWFGMVFVFLVVALTSSVVFIAYFCLLPLVLHTYSPGWMIWHICYGHWNLVMIVFHYYKATKTPPGYPPKMKTDVPFVSVCKKCIIPKPARSHHCGICKTCILKMDHHCPWLNNCVGHFNHRYFFSFCLFLTLGCMYCSVSGRHLFIDAYNTIDQLKHLEAEKQGVPVTGIGLLIGIVPSAGVAGKAVQVAQEVSQPPYTYKDRMFHKSVIYMWVLTSTVSVALGALTLWHALLITRGETSIERHINGKEAKRLAKRGRVYRNPFSYGKLNNWKVFFGVEKRSHWLTRVLLPSGHAPYGDGLTWDIYPLKKDMMPV
Protein: Mitogen-activated protein kinase kinase kinase ANP1 (EC 2.7.11.25) (Arabidopsis NPK1-related kinase 1) (O22040)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in an oxidative stress-mediated signaling cascade that phosphorylates downstream MAP kinases MPK3 and MPK6. May suppress auxin signaling that promotes cell cycle. Functionally redundant to ANP2 and ANP3 in the positive regulation of cytokinesis.
Interaction partners:
- Mitogen-activated protein kinase kinase 5
- Mitogen-activated protein kinase kinase 4
- Kinesin-like protein KIN-7A
- Mitogen-activated protein kinase kinase kinase 2
- Kinesin-like protein KIN-7B
Sequence:
MQDFFGSVRRSLVFRPSSDDDNQENQPPFPGVLADKITSCIRKSKIFIKPSFSPPPPANTVDMAPPISWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLKHPFVMGKHKESASTDLGSVLNNLSTPLPLQINNTKSTPDSTCDDVGDMCNFGSLNYSLVDPVKSIQNKNLWQQNDNGGDEDDMCLIDDENFLTFDGEMSSTLEKDCHLKKSCDDISDMSIALKSKFDESPGNGEKESTMSMECDQPSYSEDDDELTESKIKAFLDEKAADLKKLQTPLYEEFYNSLITFSPSCMESNLSNSKREDTARGFLKLPPKSRSPSRGPLGGSPSRATDATSCSKSPGSGGSRELNINNGGDEASQDGVSARVTDWRGLVVDTKQELSQCVALSEIEKKWKEELDQELERKRQEIMRQAGLGSSPRDRGMSRQREKSRFASPGK
Protein: Dammarenediol II synthase (Dammarenediol synthase) (PgDDS) (EC 4.2.1.125) (Q08IT1)
Organism: Panax ginseng (Korean ginseng)
Function: Component of the dammarane-type triterpene saponins (e.g. ginsenosides or panaxosides) biosynthetic pathway. Oxydosqualene cyclase that produces specifically the 20S isomer of the triterpene dammarenediol II.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P48449}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MWKQKGAQGNDPYLYSTNNFVGRQYWEFQPDAGTPEEREEVEKARKDYVNNKKLHGIHPCSDMLMRRQLIKESGIDLLSIPPLRLDENEQVNYDAVTTAVKKALRLNRAIQAHDGHWPAENAGSLLYTPPLIIALYISGTIDTILTKQHKKELIRFVYNHQNEDGGWGSYIEGHSTMIGSVLSYVMLRLLGEGLAESDDGNGAVERGRKWILDHGGAAGIPSWGKTYLAVLGVYEWEGCNPLPPEFWLFPSSFPFHPAKMWIYCRCTYMPMSYLYGKRYHGPITDLVLSLRQEIYNIPYEQIKWNQQRHNCCKEDLYYPHTLVQDLVWDGLHYFSEPFLKRWPFNKLRKRGLKRVVELMRYGATETRFITTGNGEKALQIMSWWAEDPNGDEFKHHLARIPDFLWIAEDGMTVQSFGSQLWDCILATQAIIATNMVEEYGDSLKKAHFFIKESQIKENPRGDFLKMCRQFTKGAWTFSDQDHGCVVSDCTAEALKCLLLLSQMPQDIVGEKPEVERLYEAVNVLLYLQSRVSGGFAVWEPPVPKPYLEMLNPSEIFADIVVEREHIECTASVIKGLMAFKCLHPGHRQKEIEDSVAKAIRYLERNQMPDGSWYGFWGICFLYGTFFTLSGFASAGRTYDNSEAVRKGVKFFLSTQNEEGGWGESLESCPSEKFTPLKGNRTNLVQTSWAMLGLMFGGQAERDPTPLHRAAKLLINAQMDNGDFPQQEITGVYCKNSMLHYAEYRNIFPLWALGEYRKRVWLPKHQQLKI
Protein: Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10) (Q9WTN0)
Organism: Mus musculus (Mouse)
Function: Catalyzes the trans-addition of the three molecules of isopentenyl diphosphate (IPP) onto dimethylallyl pyrophosphate (DMAPP) to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
Subcellular location: Cytoplasm {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O95749}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:O95749}.
Interaction partners:
- Farnesyl pyrophosphate synthase
- Diphosphomevalonate decarboxylase
- Squalene synthase
- Isopentenyl-diphosphate Delta-isomerase 1
- Isopentenyl-diphosphate delta-isomerase 2
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- All trans-polyprenyl-diphosphate synthase PDSS2
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- Protein farnesyltransferase subunit beta
- All trans-polyprenyl-diphosphate synthase PDSS1
Sequence:
MEKTKEKAERILLEPYRYLLQLPGKQVRSKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDSSKLRRGFPVAHSIYGVPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDTYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLDTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVQYLEDVGSFAYTRHTLRELEAKAYKQIEACGGNPSLVALVKHLSKMFTEENK
Protein: Light-dependent chlorophyll f synthase (Chl f synthase) (EC 1.-.-.-) (Super-rogue PsbA4) (Sr-PsbA4) (P0DOC9)
Organism: Chlorogloeopsis fritschii (strain PCC 9212)
Function: Synthesizes chlorophyll f or chlorophyllide f (Chl f, 2-formyl chlorophyll a), probably by oxidation of chlorophyll a or chlorophyllide a and reduction of plastoquinone. The reaction is probably light-dependent. Chl f absorbs far red light (FRL, 707 nm in 100% methanol), and is synthesized when cells are grown in FRL, where it provides the advantage of extending the spectral range of harvested light in terrestrial cyanobacteria. When ectopically expressed in Synechococcus PCC 7002 (which does not grow in FRL and does not make Chl f) produces Chl f (0.059% of total chlorophyll).
Subcellular location: Cellular thylakoid membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P51765}.
Interaction partners:
Sequence:
MKLESDHVIATSDSSDYTSEPTANKLSKRRKKVNYWEKFCSWVTSTENRLYVGWFGVLMIPCVLTAATVFIIAIIAAPPVDMDGIGVPISGSILSGNNIITAAVVPTSAAIGLHFYPIWEAASIDEWLYNGGPYQLIVLHFLIGIIAYQDREWELSYRLGMRPWISLAFTAPVAASVSVLLIYPVGQGSLSAGMPLGISGTFHFMLQFQADHNILMSPLHQLGVIGVLGGAFAAAMHGSLVTSTLIRSHNHSESESINKGYKLGQQHPTYNFRSAQVYLWHLIWQRVSFPNSRKLHFFLAALPVAGIWSAALGVDIAAFDFDYLQFHQPELKSQGQIIHTWADTIDWASLGIKVLDERHIYDFPENLTAGEVVPWK
Protein: Elongation factor G (C6KSM4)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Small ribosomal subunit protein eS30
- Ribosomal protein S16, mitochondrial, putative
- 40S ribosomal protein S11, putative
- 40S ribosomal protein S18, putative
- 60S ribosomal protein L6, putative
- 40S ribosomal protein S11
- 60S ribosomal protein L5, putative
- 40S ribosomal protein S3
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S19
Sequence:
MIKLFSSKRYNNNNKILLFCLVILILYKYTYSLHNRWNKNNNVYLSNGKVKREKRNGRGKLYILNRYVRNDIIKPHKNIIKNIFRLKLVNGSTKNVELENYRNIGIIAHIDAGKTTTTERILYYTNVIKKIGEVHEGLSTMDYLDIEREKGITINAAVTTCYWNGSEKNLEDYRINIIDTPGHVDFTAEVEKSLRVLDGGVVVFDSSEGVESQSETVWKQANQYNISRIIFLNKLDKVGANFEGCIEEIKRKLNKKILILYVPVFEMSKFISTIDILKEKMIVYKNAHDFIFEDIPKEHYNLFLKYKNLLFEQIAENFNSFLDNYLNDKAMNIQEIEYYIRKLVVEEKYNVVMCGSALKNKNVQMLLDMVVKYLPSPIDSIKNYKKQIIYIHDVNRRGEKIVPANSESNLKKEKVMLKKNINKGEEHNVENKIPAHEINKDSMNIKKGTTESDTSSSTCVADSNNISGPNNISSERSQNNMKDDQINYQDSISDELNESNIKNYKRKMVGLIYKIMNDQHLGNINYVRIYEGQINRGEFIYNNRTKKSEKISKIFFIHSSEKYELENAKAGDIVGLVGLKDTQIGDTLSNVFLRAELKRIKDIPPIISYYIYNKNKNEYEKLINALIKIKKEDHSFFYHINQDTKDLLISGVGELHLQIIINKIEKDFNIPIIYGKPQISYKETFVESVKARGKYIKQSGGRGQYGDVHIEIEPMYNYNEQEDEEGEQTDQEQNGVDEKEKKEQKYIEQDIDNNSMNINTSEVNNNIIIKNEITCGAIPSVYFDAIYTGIREQCNMGILFNSPVINIVVRIVDGSFHPVDSNEHAFKLAAGLAIKEAAKKTSIRLLEPIMNLNVTVPTEYLGDVISDLVKKRGKIQHIDESDEFTKEITARAPMASVLSYVSDLRKITKGRGNYTMTLHKYSLVPEYIQEQILQKKE
Protein: K Homology domain-containing protein (B9F4C9)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MADDHYSSKRKYDDPSPPPRRTGFSSAPPAASPPSGGAPATLFNAAEAKRPRLDAGGDDDDAGAGVGSLGSSGGGGGGRATGLGFSSSAGGGHGSAIPSLSSHGSTPQYSSYGGYQGTSKTIEIPNGRVGVIIGKSGETIKNLQLQSGAKIQVTRDLDALPGSQTRPVELSGTPDQISRAEQLINEVLAEADAASSGNLSSRKYNAPQPGADQFQMKIANNKVGLVIGKGGETIKSMQAKSGARIQVVPLHLPPGDPATERTVYIDGTQEQIETAKQLVIEVTSENRARNPMSGGYSQQGYRPPRPQSNWGPHGGAPMQQPGYGYMQPGAYPGAPPQYGAPQQPYGSYPPASGGYQTGWDQSSNQQSQQAPPGTGYDYYNQQQQPQQQQSAPGTAAPGDATSYNSSQPPAYASQGYDSSYAQQSGGQQQAYDYSSYYQTQGQQQGYSQQTGYDQQGYGTSGYGSAANSTQDGSAPSYGAQGVAGQASPGQQTSTPAAGSHPGYSSQPPTSAASSYPVQGSAPQSGYGAPPPQTGYGTQPQPQGGYSQGSYGAPPQGQKAPPNTSPYGQAPPPGSAPGGYGQYGYSQNQQGYGAPPPYPGAPAASHPGYGQQQSYGDPYGSGSYGQPAAYSTEATTAAASQDQSASAPATGAAPATTAAPAPTAPENSGAQSPAS
Protein: Electron transfer flavoprotein subunit alpha (Alpha-ETF) (H0YKF0)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305, ECO:0000256|PIRNR:PIRNR000089}.
Interaction partners:
Sequence:
MFRAAAPGQLRRAASLLRFQSTLVIAEHANDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAATSGGSASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPMESHSTAQAGVQWCHLGFKQFSCLSLPSS
Protein: Ankyrin 2 (H0Y931)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
XNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKELTEELGELEASSDEEAMVTTRVVRRRVIIQGDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIRRYVSSEGTEKEEIMVQGMPQEPVNIEEGDGYSKVIKRVVLKSDTEQSEVTLCEPSILSSTSQFQAEPVEGRRVSKVVKTTVVLGERMEKHLGDSSLATDLPSAKDDFEEDNNE