wanglab/gogpt-training-data huggingface dataset:
Protein: Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) (Q11068)
Organism: Caenorhabditis elegans
Function: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:P26572}; Single-pass type II membrane protein {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P26572}.
Interaction partners:
- ILEI/PANDER domain-containing protein
- Alpha-mannosidase
- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Mannosyl-oligosaccharide 1,2-alpha-mannosidase mans-2
- alpha-1,2-Mannosidase
- alpha-1,2-Mannosidase
- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Alpha-
- GLYcosylation related
Sequence:
MHAVTKIFIIFIFVFILWTLYVENDITNRTRNTDNIDDLLESANRLERLLKFEAKKIAALAEDVHKIRANRKGKHVIMEEMVSQDLKQWKDPIPVLVFSCNRAMAVRDHVEKLIRYRPSQEKFPIIVTQDCDNENVKNEVKKFGDKVEYIKHLAGDKANITIPPSHRQYTAYYRIARHYKLALNHVFVDKGYSSVIITEDDLDISPDFFSYFSSTRYLLENDEKLWCVTAWNDNGKQENIDMTAASTLYRSDFFAGLGWMMSSKTWHELEPIWPVGFWDDWMRDPARRKDRQCIRPEISRTGMMSYGKEGASKGQFFSKHLAKIKVNDKYINFGKIDLDYLLPANFAKKTNLEVMKEAVELSIDNVASFVLSSENKGKSVRVMYDGNIDYIRKADKLHIMHDFKAGVPRTAYDGIVTCFINGIRIYLVPDRTKVSAYNPDWSVPPSFGE
Protein: Neurturin (Q811Q5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- GDNF family receptor alpha-1
- GDNF family receptor alpha-2
- Proto-oncogene tyrosine-protein kinase receptor Ret
- GDNF family receptor alpha-3
- GDNF family receptor alpha-4
- Beta-nerve growth factor
- BDNF/NT-3 growth factors receptor
- Syndecan-3
- Neurotrophic factor BDNF precursor form
- Persephin
Sequence:
MRCWKAAALVSLICSSLLSVWMCQEGLLLGHRLGPALAPLRRPPRTLDARIARLAQYRALLQGAPDAVELRELSPWVARPSGPRRRAGPRRRRARPGSRPCGLRELEVRVSELGLGYTSDETVLFRYCAGACEAAIRIYDLGLRRLRQRRRVRKERVRAHPCCRPTAYEDEVSFLDVHSRYHTLQELSARECACV
Protein: Ubiquitin-associated protein 2-like (Protein NICE-4) (RNA polymerase II degradation factor UBAP2L) (Q14157)
Organism: Homo sapiens (Human)
Function: Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage. Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs) (By similarity). Required for efficient formation of stress granules.
Subcellular location: Nucleus {ECO:0000269|PubMed:35633597}. Chromosome {ECO:0000269|PubMed:35633597}. Cytoplasm {ECO:0000269|PubMed:35633597}. Cytoplasm, Stress granule {ECO:0000305|PubMed:29395067}. Note=Associates with nuclear chromatin. {ECO:0000269|PubMed:35633597}.
Interaction partners:
- Regulatory-associated protein of mTOR
- Serine/threonine-protein kinase mTOR
- Polycomb complex protein BMI-1
- Ras GTPase-activating protein-binding protein 1
- Histone-binding protein RBBP7
- Histone-binding protein RBBP4
- Protein PRRC2C
- Polycomb group protein ASXL1
- Polycomb protein EED
- Histone deacetylase 2
Sequence:
MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTSAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSTMENDSSNLDPSQAPSLAQPLVFSNSKQTAISQPASGNTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN
Protein: histone acetyltransferase (EC 2.3.1.48) (F1NGB5)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAENLLDGPPNPKRAKLNSPGFSASDSTDFGSLFDLENDLPDELIPNGELGLLNSSGNLVPDAASKHKQLSELLRGGSGSSLNPGIGNVNSNSPVQQGVGSQVQGQPNSASIGNLGAMGKSPLNQGDSSASGLAKQVASTSGPTTPASQTLNSQAQKQVGMVTSSPATSQTGPGICMNTNFSQTHQSLLNSNSGHSLMNQPQQGQGQMAGHTGLNTAQTGAITKMGMAGNTSPFGQPFSQTGGQQMGATGVNPQLPNKPGMANSLPAFPADIKSTPVTSVPNMSQMQTQVQQVGIVPTQAMATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACALPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQPLLGSPAGGMQNSIGSVGTGQQNNPSLSNPNPIDPSSMQRAYAALGLPYGNQPQTQLQPQVQGQQPAQPQAHQQMRTINALGANQMNLPTGGITTDQQASLISETALPTSLGTNNPLMNDGTNSGNVGNLSSMPTAAPPSSTGVRKAWHEHVTQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGTQPALQTPGPQPPGIPQVAAAMGQAQPVRPPNGPMSMTTVPISRMQVSQGMNQFNPMSIGNVQMPQAPMGPRAASPMNHPVQMNNMGAVPAMAMSPSRMPQPQNMMGAHSNNMMGQAPTQNQFLPQNQFPASTGAMNVNNVGMGQSAAQAGVAQQGQVPSAALPNSMNMLGPQSGQLCPPVTQPPLHQTTPPVSTAAGMPPIQHQTPTGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPNATQTQSTPTGQTAAQAQVTPQPQTPVQPQSVPTPQPSQQQPTSVQAQPPGTPLSQAAASIDNRVPTPASVASADTNSQQLGPDAPMLESKSEVKTEETEPETSETQVEAKTEVEEDLQGSSQTKEETDGTELKQEPMEIEEKKPEIKVDAKEEEESGTNGTTSQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCTKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRTRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHDHKMVKWGLGLDDESNSQGEQQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSATPGTPTQQPSTPQTPQPPPQPQPSPVSMSPAGFPNVSRTQPPTTVSTGKPANPVAAPPPPAQPPPAAVEAARQIEREAAQQQQQQLYRVNNINNGLPPGRPGLVNPTVGSVSQMQQVGMNVPRPSPVSGPVMSNMQPGQWQSPPMPQQQAMQPGMARPVMPMATAQAVAGPRMPGVQQPPRSIPPNALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQAGIQPQPGMQQPQTGMQQPGMHAQPGLQNMNAMQAGVQRPSVPPQQQGIGAMNPQGQAINIMNPGHNTSMASMNHPQYREILRRQLLQQQQQQQQQQGGAGMAAGMAGHSQFQQPQGPGGYPQAMQQQRMQQHISIQGGSMGQMAQMGQLNQMGQPGLGADGTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSSQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLGNPEQSAMLPQLNTPNRSALSNELSLVGDTTGDTLEKFVEGL
Protein: CrmE protein (TNF-alpha-receptor-like protein) (Q8UYL3)
Organism: Vaccinia virus
Interaction partners:
Sequence:
MTKVIIILGFLIINTNSLSMKCEQGVSYYNSQELKCCKLCKPGTYSDHRCDKYSDTICGHCPSDTFTSIYNRSPWCHSCRGPCGTNRVEVTPCTPTTNRICHCDSNSYCLLKASDGNCVTCAPKTKCGRGYGKKGEDEMGNTICKKCRKGTYSDIVSDSDQCKPMTR
Protein: Protein-protein interaction regulator family protein (F4HZI8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- SAP domain-containing protein
- Histone deacetylase complex subunit SAP18
- Protein mago nashi homolog
- At2g29210/F16P2.41
- Regulator of nonsense transcripts UPF3
- RNA-binding protein Y14
- Polyadenylate-binding protein 1
- Polyadenylate-binding protein 3
- Polyadenylate-binding protein 2
- Eukaryotic initiation factor 4A-III homolog
Sequence:
MGDTALEKTAEELRHEIDELHRQQREITERLRDPRGLRRGGFSNVAPRNQGRRGFPRPAERNDVEDEPPAKRRLSSAVVKVDGEDVSKDGEFPVDGNGTQVKVGENGTSDQSDKKQSGLHRGSWSQRDAEQRRTNKRYEAFALPEPAPRVLPKNEDPKLVNRNRRMLGNLLGTLEKFRKEDKQRSGTDAYARRTAALQRAEEKAREESERLRLQERENLTEKRRRDLTLRARVAAKAEQKKLELLFLQWSEHQKKLSNFISDEIANCYVFHLQVIFYFGPKSVHIDNFIEAKISFHSRAYKGNVWCYRTKAEPRIYYAPVKPLEEDTSEVEQQKERTFLEWKAARRQEVSEYQKEIEEQCLGNVEKELERWQNARKARKANNEGMNLQETMDKELETHRMEHGPKKRKIPGGGVGDEDEEDEVEDINGGEDEMIMDDLLEEGGDGTIKEEVATDTVKAEAVEEDIKHEVL
Protein: At5g05090 (Homeodomain-like superfamily protein) (Similarity to unknown protein) (Q9FF65)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MREEDSNWFAKWEEELPSPEELIPLSQSLITPDLAIAFDLHRNNNSNSGQPLPQTTPPQPNSSAEIAGDSTGDEPARTLKRPRLVWTPQLHKRFVDAVAHLGIKNAVPKTIMQLMSVDGLTRENVASHLQKYRLYLKRMKSGGGGGGSGDSDHLFASSPVPPHFLHPTSRQSSDLFIPSFVPISTQQQHIAAPPSQFLHRQISAVNFTSPTKATDQAMFLARQQSELQQPVFKPSSLHLHSQVANYTQDLKSGAKTVLTLFPTRDD
Protein: Mas-related G-protein coupled receptor member H (Q7TN38)
Organism: Rattus norvegicus (Rat)
Function: Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MEPLATTLCPQECTQTTRNETPNETTWSSEHVTKYTYISISLVICSLGLVGNGLLIWFLIFCIKRKPFTIYILHLAFADFMVLLCSSIIQLVNTFHIYDSTLVSYAVLFMIFGYNTGLHLLTAISVERCLSVLYPIWYHCRRPKHQSTVACTLLWALSVLVSGLENFFCILEVKPQFPECRYVYIFSCTLTFLVFVPLMVFSNLILFIQVCCNLKPRQPAKLYVIIMATVILFLVFAMPMKVLLIIGYYSNSTDASVWKSLPYLNMLSTINCSINPIVYFVVGSLRRKRSRKSLKEALQKVFEEKPVVASRENEVQFSLPL
Protein: Vesicle-fusing ATPase (EC 3.6.4.6) (O88975)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU367045}.
Interaction partners:
Sequence:
EQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIK
Protein: Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155) (P15151)
Organism: Homo sapiens (Human)
Function: Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.
Subcellular location: [Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform Beta]: Secreted.; SUBCELLULAR LOCATION: [Isoform Gamma]: Secreted.
Interaction partners:
- T-cell immunoreceptor with Ig and ITIM domains
- CD226 antigen
- T-cell surface protein tactile
- Nectin-3
- Cytotoxic T-lymphocyte protein 4
- Natural cytotoxicity triggering receptor 3
- NKG2-D type II integral membrane protein
- NKG2-A/NKG2-B type II integral membrane protein
- Programmed cell death protein 1
- Hepatitis A virus cellular receptor 2
Sequence:
MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
Protein: Vasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into: Arg-vasopressin (Arginine-vasopressin); Neurophysin 2 (Neurophysin-I); Copeptin] (P01186)
Organism: Rattus norvegicus (Rat)
Function: Neurophysin 2 specifically binds vasopressin.
Subcellular location: Secreted.
Interaction partners:
- Vasopressin V1a receptor
- Vasopressin V2 receptor
- Vasopressin V1b receptor
- Aldehyde dehydrogenase, dimeric NADP-preferring
- Aldehyde dehydrogenase 1A1
- Aldehyde dehydrogenase
- Oxytocin receptor
- Cytochrome P450 2E1
- Oxytocin-neurophysin 1
- Solute carrier organic anion transporter family member 3A1
Sequence:
MLAMMLNTTLSACFLSLLALTSACYFQNCPRGGKRATSDMELRQCLPCGPGGKGRCFGPSICCADELGCFLGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCSDESCVAEPECREGFFRLTRAREQSNATQLDGPARELLLRLVQLAGTQESVDSAKPRVY
Protein: NUDIX hydrolase, conserved (Q383U8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ribose-phosphate diphosphokinase
- ribose-phosphate diphosphokinase
- ribose-phosphate diphosphokinase
- Ribose-phosphate pyrophosphokinase, putative
- 5'-3' exoribonuclease 2
Sequence:
MRDRYIRVGLNVLQERKYLRLCEITYTAEKNGTPEGAREVGDISASKWELVQRTTRQVPLDRYQRTPAPLAVDSTEICAFLSRGNESFLILVAQYRPPLDAVVIEFPAGLIDPGEDAKVAALRELKEETGYSACVEDVFDVSDAVCLEPGLSDSCCQFVKIRVDGDSKINCKPQPQLDDGEDIDVILLPLKLGKNVESDVTPTKMLKRLVAQKEGMNNRTIVDARLYMFLEGLSFFKHTSLKIATL
Protein: GATA transcriptional activator AreA (Q4WCP6)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nitrogen metabolite repression regulator NmrA
- Nitrite reductase [NAD
- Nitrate reductase
- Importin subunit alpha
- GATA-type transcription factor sreA
Sequence:
MSGMSHGGAPKAARPTPTAVSASSGYDIADADRSSSSHFHHTSQLSDDFSLGSPLSPPDSAHVQDGLLQDSLFPEWRNAAPRDGVESPDEMQRKDPLATQIWKLYSRTKAQLPNQERMENLTWRMMAMSLKRKERERLQQNNRPSTKNSGSSEPSGIAQLRQTDRPSFARPSTSTDLASDPMNIDDFIVPIESPADRPRSPPTDKAATSSVAIPIKSRKDQSADATPVPASFPHPPQDQRRNNEFGYVPRRVRKTSIDERQFFNLQIPTRKRPAESSPQVPPVSNAMLAQDPNFSAGVPDYTLDNASSGFALHSNTQNHHNNNNLTSPGVPFGLDTFSLGEDPILSSAGPYQAHFTFSPSDSPMTSANPFANVYAQTPIASSLNSTEFFSPPPSGYQSSVSTPQPTYDGDHSMYFDMPSIDARTQRRIPNYITHRSNLSASLQPRFMFNNNTGSEQQHGMTHGSNSSSAVHSPNYTMSQSQHVDPTQVLNPSDFPTSNTHAGIFSFGADSDNEDDDANNYTERAGLAMPADFGDDNAGDMNGLNWDGQFPGSFHSLSGFSVQHRKHVTIGSADMMDTPSEWNQGGSLGRTHGSAASVSEVRNREQDPRRQKIARTTSTPNTNQLLRQSMNNTSHTSPNTPPESGLSSAVPSRPASPGGSKNGDQNNGPTTCTNCFTQTTPLWRRNPEGQPLCNACGLFLKLHGVVRPLSLKTDVIKKRNRSSANSLAVGASRSSKKSSRKNSVAQISMTTPTSSRAQSNTTSESPPAIPGGAASAAGRTAGATGKSGVVPIAAAPPKATPTSAGQSRSTVQVAPKRQRRLEKASETDAADDSNKPSTSSGGRSKVVPLAPAMPPAAVNPANHSIAGGQGASQEWEWLTMSL
Protein: Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Q6Q477)
Organism: Mus musculus (Mouse)
Function: Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (By similarity). By regulating sperm cell calcium homeostasis, may play a role in sperm motility.
Subcellular location: Membrane {ECO:0000250|UniProtKB:P23634}; Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:15078889}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Nitric oxide synthase 1
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit alpha
- cGMP-dependent protein kinase 1
- cGMP-dependent protein kinase 2
- Calcium-transporting ATPase
- Plasma membrane calcium-transporting ATPase 1
- Phospholamban
- Troponin I, cardiac muscle
Sequence:
MTNPPGQSVSANTVAESHEGEFGCTLMDLRKLMELRGADAVAQISAHYGGVQEICTRLKTSPIEGLSGNPADLEKRRLVFGKNVIPPKRPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPPGGDNEICGHIASSPEEEEEGETGWIEGAAILASVIIVVLVTAFNDWSKEKQFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKTLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGASEEEDDDDKKKKGKKQGAPENRNKAKTQDGVALEIQPLNSQEGLDSEDKEKKIARIPKKEKSVLQGKLTRLAVQIGKAGLIMSVLTVVILILYFVVDNFVIQRREWLPECTPVYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGTHYRQIPQPDVFPPKVLELIVNGISINCAYTSKIQPPEKEGGLPRQVGNKTECGLLGFVTDLKQDYQAVRNEVPEEKLFKVYTFNSVRKSMSTVIRKPEGGFRMFSKGASEIMLRRCDRILNKEGEIKSFRSKDRDNMVRNVIEPMASEGLRTICLAYRDFDGTEPSWDIEGEILTSLICIAVVGIEDPVRPEVPDAIAKCKRAGITVRMVTGDNVNTARAIATKCGILTPKDDFLCLEGKEFNSLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTAGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPLISRTMMKNILGHAVYQLLIVFLLVFAGDTLFDIDSGRKAPLNSPPSQHYTIVFNTFVLMQLFNEINARKIHGEKNVFAGVYRNIIFCTVVLGTFFCQIMIVELGGKPFSCTSLTMEQWMWCLFIGIGELLWGQVISAIPTKSLKFLKEAGHGSDKEDISRDTEGMDEIDLAEMELRRGQILWVRGLNRIQTQIRVVKLFHNNHEVAHKPKNRSSIHTFMTQPEYPADDELSQSFLDIQEGNPELVSKAGTSVLLLDGEAASHDNINNNAVDCHQVQIVASHSDSPLPSLETPV
Protein: D-aminoacyl-tRNA deacylase (EC 3.1.1.96) (Q38AP4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU003470}.
Interaction partners:
Sequence:
MRVVVQRVLEGAVTVGEEVVGSVGRGIVALVGIHHEDDMSDVDYIAHKLLSLRIWRSEDGQKTWDRNVKQVDGGILLVSQFTLMHVLKGNKPDFHLAMKPERASELFNNLREALCRDYAAHKISTGRFQSYMNINMTNDGPVTLVLDSRNK
Protein: Purine ribonucleoside efflux pump NepI (Nucleoside efflux permease-inosine) (P0ADL1)
Organism: Escherichia coli (strain K12)
Function: Involved in the efflux of purine ribonucleosides, such as inosine and guanosine. Adenosine may also be a substrate. Confers resistance to the hypoxanthine analog 6-mercaptopurine, however the level of resistance is rather low.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01189, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized protein YicN
- Inner membrane protein YbcI
Sequence:
MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFILKRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVKMKKS
Protein: Protein aurora borealis (Q8BS90)
Organism: Mus musculus (Mouse)
Function: Required for the activation of AURKA at the onset of mitosis.
Interaction partners:
- Serine/threonine-protein kinase PLK1
- Aurora kinase A
- Cyclin-dependent kinase 1
- Serine/threonine-protein kinase PLK4
- Serine/threonine-protein kinase Nek2
- HAUS augmin-like complex, subunit 6
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Centrosomal protein 192
- Inner centromere protein
- G2/mitotic-specific cyclin-B1
Sequence:
MGDVSELKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSIFKSTKLPTPGKFRWSIDQLAIINPVEIDPEEIHRQASYLRLSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHDGKQPSELHPSKCLSSHDDSPDGKKPSLPSQKCNAACQTLLSLPVDFNLEAILGDYFREEDFVAHTPGNLSSSSLRRKLFLDGNGSICDPLPSPSPGSPPCSARGSLEGQFSSSPIQNSVKKYSLGSVTTSPSAISSPTFSPIALQGGKTPLSEPRKLTFHSPEASCATASTGIVNPSIRSPYIDGCSPIKNWSPRRLRGGPQCLSSLVRIPFTLEAHSEDEEADVSCTGAAPLSTNACGEPRVVTAMSVTQSHSGIAEKERAVLDDAESERENDTVDMVDPTDTVAESTWIKEPVDDGNSPMTDSASGIAFSIENSHMCMSPLAESSVLPYESSAIQMNSDYNTQTCVSNITDIVGTERYCKENVTHTNVPVPFEVEMKSQVNNVTPGHTAQRCWMKSPRPSQCSRP
Protein: Hemagglutinin glycoprotein (Q786F2)
Organism: Measles virus (strain Ichinose-B95a) (MeV) (Subacute sclerose panencephalitis virus)
Function: Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis (By similarity).
Subcellular location: Virion membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Host cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MSPQRDRINAFYKDNPHPKGSRIVINREHLMIDRPYVLLAVLFVMFLSLIGLLAIAGIRLHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLEARATNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLSRGYNVSSIVTMTSQGMYGGTYLVGKPNLSSKGSELSQLSMHRVFEVGVIRNPGLGAPVFHMTNYFEQPVSNDFSNCMVALGELKFAALCHREDSITIPYQGSGKGVSFQLVKLGVWKSPTDMRSWVPLSTDDPVIDRLYLSSHRGVIADNQAKWAVPTTRTDDKLRMETCFQQACKGKNQALCENPEWAPLKDNRIPSYGVLSVNLSLTVELKIKIASGFGPLITHGSGMDLYKTNHNNVYWLTIPPMKNLALGVINTLEWIPRFKVSPNLFTVPIKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPSRSFSYFYPFRLPIKGVPIELQVECFTWDKKLWCRHFCVLADSESGGHITHSGMVGMGVSCTVTREDGTNRR
Protein: ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme) (Q7KN85)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
- Probable citrate synthase, mitochondrial
- Citrate synthase
- Fatty acid synthase
- Acetyl-CoA carboxylase, isoform A
- Malate dehydrogenase
- Malate dehydrogenase
- Malate dehydrogenase
- Pyruvate carboxylase
- Malate dehydrogenase, mitochondrial
- Aconitate hydratase, mitochondrial
Sequence:
MSAKAITEASGKDILNRHLNTHGAGAATCRFSTVNSTTDWSKLAVDHPWLLTTPLVCKPDQLIKRRGKLGLIGVKKNFEQVKQWIGERLNKDQKIGNAVGKLRNFIIEPFVPHTDAEEMYVCIYSHRAADTILFYHQGGVDIGDVDAKAVKLDVPVNSSLSLADVKSKLLKEVKDAGTKERIAKFVSALYTTYVDLYFTYLEINPLVVTADNLYILDLAAKLDSTADFICRPKWGEIDYPPPFGRDAYPEEAYIADLDAKSGASLKLTILNRNGRIWTMVAGGGASVIYSDTICDLGGASELANYGEYSGAPSEQQTYEYAKTILNLMTSSPKHPDGKVLITGGGIANFTNVAATFQGIITALREFQPKLVEHNVSIFVRRAGPNYQEGLRKMRDFGSTLGIPLHVFGPETHMTAICGMALGKRPIPQTASVEFSTANFLLPGGQQAQADLKAASDASEALGSGSALSPTAAKPIKLPPISADEADSAGISGAQRNGSSLNRKFFSNTTKAIVWGMQQRAVQSMLDFDFICRRDEPSVVAMVYPFTGDHKQKYYWGHKEILIPVYKKMSDAIHKHKEVDVMVNFASMRSAYESTLEVLEFPQIRTVAIIAEGIPENMTRKLIIEADKKGVAIIGPATVGGVKPGCFKIGNTGGMLDNILHSKLYRPGSVAYVSRSGGMSNELNNIISKATDGVIEGIAIGGDRYPGSTFMDHILRYQADPETKLIVLLGEVGGTEEYDVCAALKDGRITKPLVAWCIGTCASMFTSEVQFGHAGSCANSDRETATAKNKGLRDAGAYVPDSFDTLGELIHHVYGELVKTGRVVPKEEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPISEVLSKDVGIGGVISLLWFQRCLPSYVCKFFEMCLMVTADHGPAVSGAHNTIVCARAGKDLVSSVVSGLLTIGDRFGGALDGSARQFSEAYDTNLHPMEFVNKMRKEGKLILGIGHRVKSINNPDVRVKIIKEFVLENFPACPLLKYALEVEKITTNKKPNLILNVDGVIATAFVDMLRNSGSFTSEEAQEYINVGAINSLFVLGRSIGFIGHYMDQKRLKQGLYRHPWDDISYVIPEQYN
Protein: Photosystem II reaction center protein J (PSII-J) (Q2LIM2)
Organism: Oryza sp. IRGC 81916
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000256|HAMAP-Rule:MF_01305}; Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01305}.
Interaction partners:
Sequence:
MADTTGRIPLWLIGTVTGIAVIGLIGVFFYGSYSGLGSSL
Protein: Small ribosomal subunit protein eS1 (Q38BK7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03122}.
Interaction partners:
- 40S ribosomal protein S13, putative
- 40S ribosomal protein S26
- 40S ribosomal protein S27, putative
- 40S ribosomal protein S15, putative
- Small ribosomal subunit protein uS4
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S4
- 40S ribosomal protein S25
- 40S ribosomal protein S24
- 40S ribosomal protein S23, putative
Sequence:
MTLGKNKRISKGGKRGKKKAQEAMSRKEWYDVVAPKNFEVRQFAKTICNKTQGTKVAADFLRGRVYEGNLADLNKTQNEDDAYRKVKFTVQEVQGRNLLTQFHGMDMTSDRVYYLLRKWCTTIEATVEAKTADGYGLRLFLIAFTKKQENQLSKNCYAKTRLVKWVRMRATNIIRRRLAKLDINDAVSLLTRNILRDRLAKRCNPIIPLRDLRIRKVKVIRTPKFDAQALIAAHGEVPTSAEGEARVVEEAQEETA