wanglab/gogpt-training-data huggingface dataset:
Protein: Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3) (Q9UPY6)
Organism: Homo sapiens (Human)
Function: Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Nck-associated protein 1
- Abl interactor 1
- Cytoplasmic FMR1-interacting protein 1
- Abl interactor 2
- Protein BRICK1
- Cytoplasmic FMR1-interacting protein 2
- Nck-associated protein 1-like
- Actin-binding protein WASF2
- Actin-binding protein WASF1
- ABI gene family member 3
Sequence:
MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNPVADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSRRIAVEYSDSDDDSEFDENDWSD
Protein: Peptidase S53 domain-containing protein (Q2U9N2)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Interaction partners:
- Dipeptidyl peptidase 4
Sequence:
MRSSFLLAGVFGSLAAPALAIVHEKVAAVPNGWTLVKQAPESDPITLSIALARQNLDQLESKLTALSTPGNAEYGQWLDQSGIETLFPTASDEAVLRWLRNAGVTHISRQGGLVNFATSVGTVNKLFDTKFSYYKNGQVQKLRTTQYSIPDDLADGIDLVAPTVFFGKQQESVALPTHHKFAAGTKTAAGNVSCADIITPDCLADMYNFRGYKPSASSGSKVGFGSFLNESANYVDLALYEKRFNIPSQNFSVELINGATNDQNWTTASLGEANLDVELIVGVSHPLPVKEYITAGTPPFIPNALQPTPADNQNEPYLEYYEYLLAKPNSALPQVLSNSYGDEEQTVPEYYAKRVCNLIGLMGLRGITVLESSGDTGIGASCMSNDGTETPEFTPIFPATCPYLTSVGGTQAYAPEVAWDASSGGFSNYFSRAWYQESAVSKYLDQQITAETKDYYSQYTNFSGRGFPDVAAHSLTPRYEVVVKGKRATSGGTSAAAPVFAGLVGMLNDARLRAGKPTLGFLNPLLYSGALKDFTDITAGSSIGCDGVNPQTGKNVTGGGVIPYAHWNATAGWDPVTGLGVPDFMKLKDLVLSL
Protein: Large proline-rich protein BAG6 (BCL2-associated athanogene 6) (HLA-B-associated transcript 3) (G1SU30)
Organism: Oryctolagus cuniculus (Rabbit)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Nucleus {ECO:0000256|ARBA:ARBA00004123}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
Interaction partners:
- UBX domain-containing protein 1
- Ubiquitin-like domain-containing protein
- FAS-associated factor 2
- Natural cytotoxicity triggering receptor 3
- E3 ubiquitin-protein ligase RNF115
- E3 ubiquitin-protein ligase RNF115
- palmitoyl-protein hydrolase
- palmitoyl-protein hydrolase
Sequence:
MEPSDSTSTTMEEPDSLEVLVKTLDSQTRTFIVGAQMSVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTQLPSGASSGTGSASATHGGGPLPGTRGPGATVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQAQHSQPPPQTPPVAQEPGTLSSQTAEAVENDSPAREPMEAEEVEERTPVQNPELTPPGPAPTGPAPATETNTPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGSAGSTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACAPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPAPNAEAPSSGPGQASSLAPSSTTVESSTEGASTPGPAPQPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQTGGVPSAPTGPLGPPGHGQTLGSTLIQLPSLPPEFMHAVAHQITHQAMVAAVASAAAGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGALQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPPQPPAADLQFSQLLGNLLGPAGPGSGGPGVASPTITVAMPGVPAFLQGMSDFLQATQAAPPPPPPPPPPPPAPEQQSTAPPGSPSGGTGSPGGLSPESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPGNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERTSPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSQDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKQLQEDPNYSPQRFPNAHRAFADDP
Protein: Fragile X messenger ribonucleoprotein 1 (A8MQB8)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cell projection, dendritic spine {ECO:0000256|ARBA:ARBA00004552}. Cell projection, filopodium tip {ECO:0000256|ARBA:ARBA00004495}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. Cytoplasm, Stress granule {ECO:0000256|ARBA:ARBA00004210}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. Presynaptic cell membrane {ECO:0000256|ARBA:ARBA00034111}. Synapse, synaptosome {ECO:0000256|ARBA:ARBA00034102}.
Interaction partners:
Sequence:
MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
Protein: Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1) (P13053)
Organism: Rattus norvegicus (Rat)
Function: Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis. Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P11473, ECO:0000255|PROSITE-ProRule:PRU00407}. Cytoplasm {ECO:0000250|UniProtKB:P11473}. Note=Localizes mainly to the nucleus. Translocated into the nucleus via both ligand-dependent and ligand-independent pathways; ligand-independent nuclear translocation is mediated by IPO4. {ECO:0000250|UniProtKB:P11473}.
Interaction partners:
- Nuclear receptor coactivator 2
- Mediator of RNA polymerase II transcription subunit 1
- Retinoic acid receptor RXR-alpha
- Fibroblast growth factor 23
- Runt-related transcription factor 2
- 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
- Mothers against decapentaplegic homolog 3
- Parathyroid hormone
- 1,25-dihydroxyvitamin D
- Vitamin D-binding protein
Sequence:
MEATAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMDGSTGSYSPRPTLSFSGNSSSSSSDLYTTSLDMMEPSGFSNLDLNGEDSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNEIS
Protein: (H+)-ATPase G subunit, putative (EC 3.6.3.14) (Q57XF8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ATP synthase, putative
- Uncharacterized protein
- H
- V-type proton ATPase subunit a
- Vacuolar ATP synthase subunit D, putative
- V-type proton ATPase subunit
- V-type proton ATPase subunit F
- V-type ATPase, C subunit, putative
- Vacuolar proton pump subunit B
- V-type proton ATPase subunit C
Sequence:
MPPKYDNVQRLLDAERRRNEVIANAKAQKQAKVKQAKVDAEREVAAFHAEKEREYEAYRQQQEALTEKEKEQLRSDTDVWLQQLNAMAANRMQAVETMMTGLILRCQDN
Protein: Uncharacterized protein, isoform B (A0A0B4LGT9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTTLARWRAAKEVESGEKERRPYLASECHDLPRCEKFRLEIIRDISKKVAQIQNAGLGEFRIRDLNDEINKLLREKRHWENQISSLGGPHYRRYGPKMFDAEGREVPGNRGYKYFGAAKDLPGVRELFEQDPPPPPRKSRAELMKDIDAEYYGYRDDEDGVLIPLEERIERAAIQKAVQEWREKMARDGRIIDDEEEDEIYPLSGPAREAIEDAKARAAVEDPHGLLASKFTAHVPVPTQQDVQEALLRQRKRELLEKYAGGTN
Protein: Suppressor protein SRP40 (Q8I4L0)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSSRYTSSYTPSSRYGSGWDYSSSYSSSRTSRDRDTGSYRDRDYSSTSYTSTRPRYSTYASKYSTDLGKSTDRMDDYSAAPIAKDEIEELSYDAKTPTTPTEETVDAPREVLQESQISDFVEEDDDQQTEVEEVKLTLASEPEESEEEEDDEDVRKAQELLAASTQIRESSPVSSPVKEVSSAASLFANDNGNETENRTPSPTVLNAKKLGGIPWPPKSSDVKKEGGDAEALPKKRVSDLIARFNTGVVEESKKTDDAYKNEYGAGTNVGKVSTHNFA
Protein: Aminopeptidase M1 (EC 3.4.11.2) (Alpha-aminoacylpeptide hydrolase) (Q8VZH2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Metallopeptidase that binds to the auxin transport inhibitor N-1-naphthylphthalamic acid (NPA). Required for embryonic and seedling development as well as cell cycle progression. Homodimerization is required to proper localization and activity. May play a negative role in the regulation of PIN auxin transport proteins.
Subcellular location: Membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm. Note=The dileucine internalization motif may be involved in intracellular sequestration.
Interaction partners:
- Dynamin-related protein 3A
- Carboxypeptidase SOL1
- Alkaline ceramidase TOD1
- Furry
- Aminopeptidase
- Mitochondrial fission protein ELM1
- Subtilisin-like protease SBT4.15
- F-box/LRR-repeat protein 15
- Small ribosomal subunit protein uS3c
- Transcription initiation factor TFIID subunit 2
Sequence:
MDQFKGEPRLPKFAVPKRYDLRLNPDLIACTFTGTVAIDLDIVADTRFIVLNAADLSVNDASVSFTPPSSSKALAAPKVVLFEEDEILVLEFGEILPHGVGVLKLGFNGVLNDKMKGFYRSTYEHNGEKKNMAVTQFEPADARRCFPCWDEPACKATFKITLEVPTDLVALSNMPIMEEKVNGNLKIVSYQESPIMSTYLVAIVVGLFDYVEDHTSDGIKVRVYCQVGKADQGKFALHVGAKTLDLFKEYFAVPYPLPKMDMIAIPDFAAGAMENYGLVTYRETALLYDEQHSAASNKQRVATVVAHELAHQWFGNLVTMEWWTHLWLNEGFATWVSYLATDSLFPEWKIWTQFLDESTEGLRLDGLEESHPIEVEVNHAAEIDEIFDAISYRKGASVIRMLQSYLGAEVFQKSLAAYIKNHAYSNAKTEDLWAALEAGSGEPVNKLMSSWTKQKGYPVVSAKIKDGKLELEQSRFLSSGSPGEGQWIVPVTLCCGSYEKRKNFLLESKSGAYDLKELLGCSIADGSDKINGTCSWIKINVDQAGFYRVKYDDSLAAGLRNATESQSLTSIDRYGILDDSFALTMARQQSLASLLTLCSAYKKELDYTVLSNLIAISYKVVKIGADANQELMSGIKHFFIGVFQFAAGKLGWDPKQGESHLDAMLRGEVLTALAVFGHDETLKEAVRRFDAFLADRNTPLLPPDIRRAAYVAVMQRANKSDKSGYESLLRVYRETDLSQEKTRILGSLASCPDPTIVQDVLNFVLSDEVRNQDALYGLSGVSWEGREVAWKWLQEKWEYIGNTWGSGFLITRFISAVVSPFASFEKAKEVEEFFATRSKPSMARTLKQSIERVHINANWVESIKKEDNLTQLVAQLSSN
Protein: General odorant-binding protein 56d (Q8SY61)
Organism: Drosophila melanogaster (Fruit fly)
Function: Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- GEO07291p1
- General odorant-binding protein 19d
Sequence:
MKFLIVLSVILAISAAELQLSDEQKAVAHANGALCAQQEGITKDQAIALRNGNFDDSDPKVKCFANCFLEKIGFLINGEVQPDVVLAKLGPLAGEDAVKAVQAKCDATKGADKCDTAYQLFECYYKNRAHI
Protein: Ras-related protein Rab-11B (EC 3.6.5.2) (O35509)
Organism: Rattus norvegicus (Rat)
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11B plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
Subcellular location: Recycling endosome membrane {ECO:0000250|UniProtKB:P46638}; Lipid-anchor {ECO:0000250|UniProtKB:P46638}; Cytoplasmic side {ECO:0000250|UniProtKB:P46638}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000305|PubMed:14627637}; Lipid-anchor {ECO:0000305|PubMed:14627637}; Cytoplasmic side {ECO:0000305|PubMed:14627637}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:Q15907}; Lipid-anchor {ECO:0000250|UniProtKB:Q15907}; Cytoplasmic side {ECO:0000250|UniProtKB:Q15907}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q15907}. Note=Colocalizes with RAB11AFIP1 on punctate vesicles. {ECO:0000250|UniProtKB:Q15907}.
Interaction partners:
- Rab11 family-interacting protein 2
- Rab11 family-interacting protein 1
- Rab11 family-interacting protein 5
- TBC1 domain family member 1
- Solute carrier family 2, facilitated glucose transporter member 4
- Ras-related protein Rab-11A
- Phosphatidylinositol 4-kinase beta
- Rab GDP dissociation inhibitor beta
- Rab GDP dissociation inhibitor alpha
- Rab11fip3 protein
Sequence:
MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVPPTTDGQKPNKLQCCQNL
Protein: Hemolysin A (EC 4.6.1.1) (Q1R2T5)
Organism: Escherichia coli (strain UTI89 / UPEC)
Subcellular location: Host cell membrane {ECO:0000256|ARBA:ARBA00004598}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004598}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MPTITTAQIKSTLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNKLGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKKQKSGSNVSSSELAKASIELINQLVDTAASINNNVNSFSQQLNKLGSVLSNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDMLIGELASVTRNGDKTLSGKSYIDYYEEGKRLERRPKEFQQQIFDPLKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDDELQVQGNSLAKNVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSGYGHHIIDDEGGKDDKLSLADIDFRDVAFKREGNDLIMYKAEGNVLSIGHKNGITFKNWFEKESDDLSNHQIEQIFDKDGRVITPDSLKKAFEYQQSNNKVSYVYGHDASTYGSQDNLNPLINEISKIISAAGNFDVKEERSAASLLQLSGNASDFSYGRNSITLTASA
Protein: Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR) (P50637)
Organism: Mus musculus (Mouse)
Function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. According to some reports, it is not required for steroid hormone biosynthesis.
Subcellular location: Mitochondrion membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane; Multi-pass membrane protein.
Interaction partners:
- Non-selective voltage-gated ion channel VDAC1
- Steroidogenic acute regulatory protein, mitochondrial
- Golgi resident protein GCP60
- ADP/ATP translocase 2
- Peripheral-type benzodiazepine receptor-associated protein 1
- Non-selective voltage-gated ion channel VDAC3
- Non-selective voltage-gated ion channel VDAC2
- ADP/ATP translocase 4
- Acyl-CoA-binding protein
- ADP/ATP translocase 1
Sequence:
MPESWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIVWKELGGFTEDAMVPLGLYTGQLALNWAWPPIFFGARQMGWALADLLLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATVLNYYVWRDNSGRRGGSRLPE
Protein: Fanconi anemia core complex-associated protein 20 (FANCA-associated protein of 20 kDa) (Fanconi anemia-associated protein of 20 kDa) (Q6NZ36)
Organism: Homo sapiens (Human)
Function: Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.
Subcellular location: Nucleus {ECO:0000269|PubMed:22343915, ECO:0000269|PubMed:22705371}. Chromosome {ECO:0000305|PubMed:22343915, ECO:0000305|PubMed:22705371}. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8. {ECO:0000269|PubMed:22705371}.
Interaction partners:
Sequence:
MEAARRPRLGLSRRRPRPAGGPSGGRPWFLLGGDERERLWAELLRTVSPELILDHEVPSLPAFPGQEPRCGPEPTEVFTVGPKTFSWTPFPPDLWGPGRSYRLLHGAGGHLESPARSLPQRPAPDPCRAPRVEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW
Protein: Transmembrane domain-containing protein TMIGD3 (P0DMS9)
Organism: Homo sapiens (Human)
Function: Plays a suppressive role in osteosarcoma malignancy by inhibiting NF-kappa-B activity.
Subcellular location: Membrane {ECO:0000269|PubMed:27886186}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- V-set and immunoglobulin domain-containing protein 4
Sequence:
MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM
Protein: Non-selective voltage-gated ion channel VDAC2 (Outer mitochondrial membrane protein porin 2) (Q5JSD1)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
Interaction partners:
Sequence:
MATHGQTCARPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGS
Protein: Dixin-A (Coiled-coil protein DIX1-A) (Coiled-coil-DIX1-A) (DIX domain-containing protein 1-A) (Q804T6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Functions as a positive effector of the Wnt signaling pathway regulating antero-posterior neural patterning.
Subcellular location: Cell junction, focal adhesion {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- DISC1 scaffold protein.
Sequence:
MGAKQMKCLSSSSPSHTPKEEYIIAKSEDSGELVGNHTEQPQSLEDVVKSSATDPYPGPEHVVKEESSTWEEQLCAQQEQLEKEMQETRKMVSRLQALLLHGSLPEDEQTSTLSFGDTASSEQQLILTRSRLDQSMEESLDLKRELLRYKQEARNLQAVKDALQQRMSVQEDSVLQLKQELLRSSMTREELEGQNVELERKLSERNRLLSEYKKELGQKDRLLQQQQTKLDDALRRISESYHRLSGCENNGYSHMMDTSSAVFQHRMGDELQLVRDALRSLRDSFSGHDPQHHTLDTLEQGVASLVDRLHTSDTKKRPERKGSTRSPGRKANHTDRESWPSTSKIAHSHSSPVLSAAASTKVLYYTDRSLTPFLVNIPKRLGDVTLQDFKAAVDRHGSFRYHFKSLDPEFGTVKEEVFQDDAVIPGWEGKIVAWVEEDHGEGR
Protein: Uncharacterized protein (A0A1D8PJ62)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MFRNVVITVKNTIRKLNQSYKYRGQFLRLQHNSTMLNHNNNNHHHQYRSITNSKPSSLSKYPKFNSTHGKNSLSNNHISSKQLTNISLDQILLNISKCNDYNSLTKYISTINHQYLNSQNSILQLITKWIKFNNKFNNKLPSFNALNGIFESLIRRQHEVTTTKNINYVSNLLTLYLYLYRFNHSALNILPLNLIWIQYGNRLIYNIYFITYLENLFNTNQNQLCITTLINKLKTFQFDQDMEEIKILENIPRSMILYMIEMKNFDSLNFLISRFLIHKVVIDNELWNLLLQLGLENNNYQLVTLVYDNYIMKDFHQGKITLDDIILNTKLVSQNSNIDLQSFGDSLIFQILHTISMNGDIKRTEELITSHFIYKSLSNMDHGLSKELCIKIIESYCYYKPNNIKSSSFNIPDNSVKEILSLIDVMLDNQKDLSSIDFFECMNYKFKNWTITSFNENKSDSQQQHQEEEEEEEEDKKELPLLQGNKNLHNSEYGIILANLSNLHEFINIHMNYMDENNHKLKTKTIFINCLLNHIMIFLNHSGIVSLLKNLHYLKGSSIIITNNYLDSISWKLILKSLSDSTSKKCGKIYYNYLKTRQNDIEITPMMYSQLIMTCMNGDSNGYFHDVLFYIIEYFKQYSKLSSEIKGVLDYGGQYDINVKTLLDNIINWQNSNENIEILLSKLKDIQLKPIDNPIKRQYLEKYDSRDSETLMKIFQ
Protein: Eukaryotic translation initiation factor 5B (Translation initiation factor IF-2) (Q9VZP5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Eukaryotic translation initiation factor 5
- Small ribosomal subunit protein uS3
- Eukaryotic translation initiation factor 4C
- Eukaryotic translation initiation factor eIF1
- 40S ribosomal protein S15
- Large ribosomal subunit protein uL18
- Eukaryotic translation initiation factor 3 subunit C
- Small ribosomal subunit protein uS4
- FI01658p
- Small ribosomal subunit protein uS17
Sequence:
MVKAKKGKKEILTKVEGGSSVDEISDVDSDQLSLNNKQNHALKGNQAGDDDVKAVTKGVKKLNVKGKGKAGKNDDSDEEEVVPAKGKASKKSAFELLMDDDEQDEPAAQESQSEKEEKVVVSKPQKNEKKGKKAKRKGKDDDDEDLDKVLAELQAEYAGEAAPAATTVVSPEELADEFSKKKKNKKQAKQAAVAENAGEDEASDDEEGGSTVKSAAQKKKEKKERQKREAALAKQKAATEPKPKPVEKPAPEPEPVATEEVQPAAEEEEEKSSKNKKKGKKDKKAEPEEEKKDAKKKGMSASMVAAMQEQLRKRKEEEERLEREEAERIRLEDEREEARLEAVRLEAERKEKKKQREAERKARLKAEGKLLTKKQKEDRARAQALLESLKAQGLEIPDPNDKRPTRPGTRIRPNKKKGPKEEAAEEEAKAAEAEAQSAAAAAAAAAAEKAEEERVKESWDATDSEAEPEPEEETSQATNNGKTEAAEEENEDTDDDEDDDDDEDDSDDSDGDSDDSREVSVLANDPESRRLRAEARILKRQAEAEKKRSTDELRAGVVCVLGHVDTGKTKILDKLRRTHVQDSEAGGITQQIGATNVPIEAIKEQTKYVKAAAGFEHRLPGLLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESIQLLKKKKCPFIVALNKIDRLYDWKQLARRDVRDVLKEQQSNTQLEFQQRTKDVILQFAEQGLNAALFYENTDPKTYISLVPTSAISGEGMGNLLFMIADFCQNMLAKRLMYSEELQATVLEVKALPGLGTTIDAILINGKLREGQTMVVAGTDGPIVTQIRSLLMPQPMKELRVKNAYVEYKEVKAAQGVKIAAKDLEKAIAGINLLIAHKPDEVEICTEEVARELKSALSHIKLAQTGVHVQASTLGSLEALLEFLRTSKIPYSAIRIGPVVKRDVMKASTMLEHEAQYATILAFDVKIEREAQEMADSLGVKIFQADIIYHLFDKFTAYREELKQKKREEFRSVAVFPCKLRILPQFVFNSRDPIVMGVMVENGIVKVGTPICVPSKEFVDIGIVTSIESNHKQIEFARKGQEICVKIDPIPGESPKMFGRHFEADDMLISKISRQSIDACKDYFRDDLIKADWALMVELKKLFEIL
Protein: Transcription factor ETV7 (Zgc:158758 protein) (A2RV31)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU004019}.
Interaction partners:
Sequence:
MSDASSPPPLIKLQHGCNGNKPSVCSPTLPDPQNEPSSVSEAVPEELCKLPGRLRINPSLWNKEDVNLWLRWAQREYSLRRADHQGFEMNGKALCLLTKEDFRLRCPSSGDVLYELLQHVKQQRRCAIFSPSSSSGTQISHETTTGLYVPSNRSVPVCPVNPNSRAVSAACSTAQMQDRTHLFADPEHPQDMQTEIFHHSLKEKMPQISPDKSRQAIAVFSTEEPLNLSNKPERPAKNTQPSEATGRIPDCKLLWDYVYQLLSDSRYEAFIRWEDPNDMIFRVVDPNGLARLWGNHKNRANMTYEKMSRALRHYYKLNIIKKETGQRLLFRFLKTPEEIIQGRSDRAEVPESPDSPVSPDYREEALEVSPASTPTTLSPSSDHNFCISPIP
Protein: Xylan O-acetyltransferase 1 (EC 2.3.1.-) (Protein trichome birefringence-like 12) (OsTBL12) (Q8S237)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan. Catalyzes the 2-O-acetylation of xylan, followed by nonenzymatic acetyl migration to the O-3 position, resulting in products that are monoacetylated at both O-2 and O-3 positions (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q2QYU2}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MANRRKFSQAGGGGGGGVFDPFGTKQAVSSLRKGGRLPVYVAGVFFVIFVIIMYGEDIRSLTLDPIARAGTTPARIVEPVVTEERHVARVNPPRREVSSAEKAAALPLDVDERPKLATPTPTEAAKEVPKVEKIRKPKKPKTTKKKPRKPRPAKKTVAAAAGGLLGVPETCDLSKGEWVFDNTSYPLYREEQCEFLTSQVTCMRNGRRDDTYQKWRWQPKDCSMPRFDAKLFMERLRGKRFMFVGDSLNRNQWESMVCLVQSAMSPGKKYVTWEDQRVVFHAVEYNATVEFYWAPFLVESNSDDPKIHSIQHRIIKADAIAAHAQNWRGVDYLVFNTYIWWMNTLNMKIMRPGGQSWEEHDEVVRIEAYRKVLTTWASWVNDNIDPARTSVFFMSISPLHISPEVWGNPGGIRCAKETMPLLNWHGPIWLGTDWDMFHAAANVSRTAATRVPITFVDVTTMSERRKDGHTSVHTIRQGKVLTPEQQADPGTYADCIHWCLPGVPDIWNLILYTRIMSRPQLV