wanglab/gogpt-training-data huggingface dataset:
Protein: ArfGAP with dual PH domains 1 (IP4/PIP3 binding protein) (O88768)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAGERRRALLELLTRPGNSRCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWDETQVEFMTSHGNEAARATFESKVPPFYYRPTFSDCQLLREQWIRAKYERQEFLHVEKQEPYSTGYREGLLWKRGRDNGQFLSRKFVLTEREGALKYFNKNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLEGLPPSTQSHHWPHGITIVTPDRKFLFTCETESDQREWIAAFQKVVDRPMLPQEYAVEAHFKHKP
Protein: Protein kish (Q38BI6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004614}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004614}.
Interaction partners:
Sequence:
MSVFFDIEAAAYVLLLIICTATYLRQYSPTLFHRDHTELHRKFLYKCSVVGDRLSLWVATGCIVVAVRMLFVY
Protein: Protein INO4 (P13902)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcriptional activator of phospholipid synthetic genes (such as INO1, CHO1/PSS, CHO2/PEM1, OPI3/PEM2, etc.).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein INO2
- Transcriptional repressor OPI1
- Phosphatidylethanolamine N-methyltransferase
- Inositol-3-phosphate synthase
- Acetyl-CoA carboxylase
- Phosphatidyl-N-methylethanolamine N-methyltransferase
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- Importin subunit beta-3
- Vesicle-associated membrane protein-associated protein SCS2
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
Sequence:
MTNDIKEIQTIQPGLSEIKEIKGELANVKKRKRRSKKINKLTDGQIRINHVSSEKKRRELERAIFDELVAVVPDLQPQESRSELIIYLKSLSYLSWLYERNEKLRKQIIAKHEAKTGSSSSSDPVQEQNGNIRDLVPKELIWELGDGQSGQ
Protein: Protein kinase, putative (EC 2.7.1.-) (Q382V0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cyclin 9
- Transcription initiation protein, putative
- [RNA-polymerase]-subunit kinase
- Spt4/RpoE2 zinc finger domain-containing protein
- Plastid-encoded RNA polymerase subunit alpha
- DNA damage-binding protein 1
Sequence:
MGMATRSPSPRTVHSGQRQEEGNWVASVPGERTQLGTSDHVKLHPIDRCSPDIPISPPHTSAADVNDVPLAEVVHGGGFGETNIAADIGGCARLVEPATFCVACEDRQSTTLLLAHNQNALDHQKQQQPVDGEGQCPLTAHDGPPRGRLRFGLRSLRVVTEESGTTARRFLRLRRPQVGAEERAEQSIGPGDRHFAPEEGEHPLQEKTNSQFDTQPLPPMHTSVTTDGSSRTNEKVEHPGGTVQHQHTTRMAEAVNASFNGPTPSLSVCKLGKSLGSGVLLSPTPTTPILKRNNGAASRKRHSKVNVFLPHSPVPIDFSSVTTHVESKYEVGKKISEGTYGEVYIGRCRTTGEYVALKRLKVLEGLEGFPITSLREVIALQHINNERQNIAVRNGNASGSNRAKMDAIDEVVRLRDVLLSSTHNDIYLVFPYASCSLAGLMHRRFPFSEKEIAYIFRKVITAVKKLHEMGIIHRDVKADNVLINRDGSVQLGDFGLCAFEGCGTRALTPSLINLNYRPPEMLLGAVAYNAKVDIWSIGCFLSQMFLRVPPFACVRPKAEFDGAGAGNAKVDPHPKEPQQKQKLKQQGYRVQAETELAQLSLITEVLGPLGGDLDEAFPPAQCRNVSLLREVRASLTSCNSQSALRASMASLFEPSHLYSQYRGFRSWFIATAERRRRSPTYPAPSPECLDVLTAIFQLDPRKRPTAAQLLEMPFFDLSRAVSSPARRSYAAYTYAEVEVEKAELLIREEMAEKLQRYEGSHLLPYPSAA
Protein: Whirlin (CASK-interacting protein CIP98) (Q810W9)
Organism: Rattus norvegicus (Rat)
Function: Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q80VW5}. Cell projection, stereocilium {ECO:0000269|PubMed:16434480, ECO:0000269|PubMed:23055499}. Cell projection, growth cone {ECO:0000269|PubMed:12641734}. Synapse {ECO:0000269|PubMed:12641734, ECO:0000269|PubMed:16434480}. Note=Detected at the level of stereocilia in inner outer hair cells of the cochlea and vestibule (PubMed:16434480). Localizes to both tip and ankle-link stereocilia regions (PubMed:23055499). Colocalizes with the growing ends of actin filaments (By similarity). Colocalizes with MPP1 in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) (PubMed:16434480, PubMed:17584769). In photoreceptors, localizes at a plasma membrane microdomain in the apical inner segment that surrounds the connecting cilia called periciliary membrane complex (By similarity). {ECO:0000250|UniProtKB:Q80VW5, ECO:0000269|PubMed:16434480, ECO:0000269|PubMed:17584769, ECO:0000269|PubMed:23055499}.
Interaction partners:
- Unconventional myosin-XV
- Usherin
- G-protein signaling modulator 2
- Taperin
- Adhesion G-protein coupled receptor V1
- Peripheral plasma membrane protein CASK
- Peripheral plasma membrane protein CASK
- Myosin VIIA
- USH1 protein network component sans
- PDZ domain-containing protein 7
Sequence:
MNAQLDGLSVSSSSTGSLGSAAAAAGGGGGAGLRLLSANVRQLHQALTALLSEPEREQFTHCLNAYHARRNVFDLVRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWAAPDGAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSTSPPSSLPHGSTLRQHEDDRRSALHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFLSILHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESITNSAGFPGDLTEEGTNKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLDQYRGGTISVEALVMALFELLNTHAKFSLLSEVRGIISPQDLDRFDHLVLRREIESMKARQPPGPGVGDTYSMVSYSDTGSSTGSHGTSTTVSSARERLLWLIDLMENTLDLEGTCETTQGSTNALPDVSVDDVRSPSEDLPGIKPPPPPPPLAQGHDRLLGQTRKPVREDSAPLSSAAHSGIVFSAPRNRSPPPPPGIAPTPTPGPSSARDSPSSPIYASISHANPSSRKPLDTHLALVNQHPIGPFPRVQSPPHLKSPPAEAPGAGACLPPPSPSEHADAMGANQHFVLVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGETEASTSGRGRQTANTKNKNGKELPQTERTTEGANKPPGLLEPTSTLIRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHREAARVIAEAFKTKERDYIDFLVTEFNVML
Protein: Spanin, inner membrane subunit (i-spanin) (P39504)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit. The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans. Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex (By similarity).
Subcellular location: Host cell inner membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}; Periplasmic side {ECO:0000250}.
Interaction partners:
Sequence:
MHVSNFTAGLLLLVIAFGGTSIILKHKVERLETSVTEITKTANENALALNNLRIQYNYIDAMNNKNREAIAAIERENEKLRKDAKKADVVAHKPGLVEKQINNSFNKFAEDIQDLSK
Protein: Conserved protein (O53319)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Putative aminoglycoside phosphotransferase
- SnoaL-like domain-containing protein
- Probable transcriptional regulatory protein
- Conserved alanine and arginine rich protein
- Polyribonucleotide nucleotidyltransferase
- Uncharacterized protein
Sequence:
MPQMLGPLDEYPLHQLPQPIAWPGSSDRNFYDRSYFNAHDRTGNIFLITGIGYYPNLGVKDAFVLIRRADIQTAVHLSDAIDSDRLHQHVNGYRVEVVEPLRKLRIVLDETEGVAADLTWEGLFDVVQEQPHVLRSGNRVTLDAQRFAQLGTWSGRIVVDGERIAVDPATWLGSRDRSWGIRPVGEPEPAGRPADPPFEGMWWLYVPLAFDDFAVVLIIQEEPDGFRSLNDCTRIWRDGHVEQLGWPRVRIHYRSGTRIPTGATIEASTPDGAPVHFDVESKLAVPTHVGGGYGGDSDWSHGMWKGEKFVERRTYDMTDPTIIARAGFGVIDHVGRALCRDGDGNPVQGWGLFEHGALGRHDPSGFADWSTLAP
Protein: Concanavalin A-like lectin family protein (F4IZV1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Putative L-type lectin-domain containing receptor kinase V.6
- Putative L-type lectin-domain containing receptor kinase V.8
- L-type lectin-domain containing receptor kinase V.7
- Receptor like protein kinase S.3
- Concanavalin A-like lectin family protein
- L-type lectin-domain containing receptor kinase VI.2
- L-type lectin-domain containing receptor kinase V.5
Sequence:
MAIFKTLSFLVLLCFEIHGTAGVDFTFSFDEFVKSQSFDKSVALFGDSKLVNDSSSIQLTDSVNRTEGRVFYKKPINLFQGKERNSVIFSTYFSFSMPNEIGDVLAFVMVPSTLDLSLFGKKDYSSSALGFLLEYAKNETVVAFEFDISKRGNRARVLIGRPESAKIRNLSFVGDLMMDDGGILSCMIDYEASSKRMRVRFRKRGSIKMFDPFFSFSVDLEKLWKGGEVMVGLSSANGNSSKPHFLHSWSFEIWHLDPIWVQPAPLGPNEGLKPDVSTEMEEGRENSECIWRMLGALVLAAVCGAVGAMSAMYLWTICSVRRSMAVVPEECAVSIVVVAVKDGKK
Protein: DNA mismatch repair protein (Q803R6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005813}.
Interaction partners:
Sequence:
MAVQPKQNLSMDSASEHGFLNFYFSMSDKPDTTVRVFDRNDYYTVHGKDAIFAAKEVFKTNGVIKNLGSGNRRLESVVLSKMNFESFVRDLLLVRQYRVEVYKNASKSSKEHDWQIAFKASPGNLTQFEEILFGSGGGPAEGAVGVVGVRLGTGTDGQRVVGVGYVDSTLRKLGVCEFPDNDQFSNLEALLVQIGPKECVLPAGDSGGDQGKLKQVVQRGGILLTDRKKSEFTTKDIVQDLNRLLKARKGETVSSAALPEMEKKIAMSCLEAVIKYLELLADEANFGSFKMTTFDLNQYMRLDNAAVQALNLFQGSSDDATGTHSLAGLLNKCRTPQGQRLVNQWIKQPLIDKNKIEERLDLVETFVEDSELRKSCQEDLLRRFPDLNRMAKKFQRQSSNLQDCYRVYQSVGQLPNVVLALERYSGKHQVLLHAAFISPLNDLISDFSKFQEMIETTLDMNQVEHHEFLVKPSFDPTLSDLRENMDRLEKAMQAALSSAARELGLEAAKTVKLESNAQIGYFFRVTCKEEKSLRNNKKFTTLDVQKNGVRFTNSKLSSLNEEYTKSREEYEEAQNAIVKEIISIAAGYVDPVQTLNEVIAQLDAVLSFAVVSHAAPVPFIRPKILEKGSGRLVLKAARHPCVEAQDEVAFIPNDVTFIRGEKMFHIITGPSMGGKSTYIRQVGVIVLMAQIGCFVPCDEAELSVVDCVLARVGAGDSQIKGVSTFMAEMLETAAILRSATEDSLITIDELGRGTSTYDGFGLAWAISEYIATRLKSFCLFATHFHELTALAQQVPTVRNLHVTALTTDSTLTMLYKVKKGVCDQSFGIHVAELASFPKHVIANAREKALELEEFQDISSVGEEAGPKAKKRCMEKQEGERIIEAFLAKVKSMPVDGMSDKAVKEELRKLKAEVISQNNSFVNEIVSRSGKVKLSSA
Protein: Insulin receptor substrate 53 kDa, isoform E (X2JCT5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEAEEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQSGTGDIGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESYQKAVSTMKKQRKKKATPENTEKELRSLQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLERQCSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAAYESGYSTSNGHNNNNISSSSSSGNNNTSGNMRRLERIKDGDDDHLQGHGAQLKKSRSIDAPYGDMRTLHERENLSGLGGTGPAHYAQNSLPRAKSDFNLALVGTGQSSANKHKIIEEQLATLGDDQRGDQRPLVKALYAYMPSGENQLSFEEGDRIALVGGKAKGWQFGENLRTQHFGWFPVAYTNAEVAEVTTSGGRRYENMLMSYERNGGGSGSGSGGGGLRSYQQQQDYEAQLELMESHEATYRRRRNHSAEDSSPTRMFGDTIKQQKKYRPGSGANPRPGPPPTLPAPVPNGPQSQSSRMLNSSQSFCASNGGGVNAAVERRKQKLLNGVQSSKNHPSGKSGVAAKTSLHSSNDSGFANEPPPQPEVDYSDEEPATQRVAIRASQFATVKLRHTKTNDRSAPMIYRSVNK
Protein: AO66 ankyrin (Q8MQG0)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MSNEGDPPQPQQQQPESQEVQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLRTVTETTVITETTTVDERYKPQNPEAMNETMFSESEDEGQAAEHEAVAAHEKDFSDNLTQGLQDSTGVHMIHTGEQLLQRSQELENGGAIPKINSGGMSPEKEFAKIAPVATSSPIATSNSQSFGIAPRAGSISGQFQQQPLHGAGPEDNLEELVRRAQNHPINAGNYDNGGVAMLENGHADNVPIGHHVTQPSFLISFLVDARGGAMRGCRHSGVRIIVPPRKASQPIRVTCRYLRKDKLAHPPPLSEGEELASRILEMAPAGAKFLGPVILEVPHFASLRDREREIVILRSDDGQHWKEHQLEATEDAVQEVLNESFDAEDLAQLDDLQTPRITRILTSDFPMYFAVVTRVRQEVHCVGPEGGVIISSVVPRVQAIFPDGSLTKTIKVSVQAQPVPQEMVTRLHGNRVAVSPIVTVEPRRRKFHKPITLCIPLPQSNNRGMLTQYSGQQGQEPPTLRLLCSITGGSAPAQWEDITGTTQLTFTGDEVSFTTTVSARFWLMDCQTPRDAARMAQEVYNEAISIPYMAKFAVFARRTFPVEGQLRVFCMTDDKEDKTLEKQEHFKLIAKSRDVEVLKGKHQFLEFSGNLVPITKSGDQLSLFFLPFQENRLAFMVKTRSNDDNEAATEGRIGFMAEPKIRSDALPPQQPICTLAISLPEYTGEIKTAPPPKKDLTPFEQRYGSALEKDLPEFVHQNVLKGIGADWPRLGRALEVPHRDIQHIRQNYPGQECKNTLKIWIHLKKEDANQDNLDQALRQIGRDDIVRSIAYGEPDALINYSQADSPSQKREPIRHFEEVPAATLVKREVRTEDLVTREPVQPTHHVEQATTVVQEPSYSAPVHHSPVPEEPEMEEEAPVAEMRTVVRTERHVHDSEDGPVVEERTITTTYEDDVAVNENIVDRTVPLNEDEQQKWEELNRLADESSPSPAQRSTIVAESTSEQVPEDVEQSVESESHREDDGTIVTTTVTTSHISASGAEQHSGQDSGTTQKKETAEEGFTNEDGSVVVSKKMTRVVTTTRTTLPGEGEEPSAPGE
Protein: Succinyl-CoA:3-ketoacid-coenzyme A transferase (EC 2.8.3.5) (Q386P1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- hydroxymethylglutaryl-CoA lyase
- Hydroxymethylglutaryl-CoA synthase
- Enoyl-CoA hydratase/Enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase, putative
- 3-oxoacyl-[acyl-carrier-protein] reductase
- propanoyl-CoA C-acyltransferase
- HotDog ACOT-type domain-containing protein
Sequence:
MLRRTNFFRIGLDKVMSLSSAVQDIKNGATLAVGGFGTGGMPHAIMQEIKKMGVRDLIIYSDGAGVDGYGIGVLFENKQINKMIVSYVGNNKIFARQYLEGDVELEFCPQGSLAERMRAGGAGIPAFYTPTAVGTVLQTGGQITKYDKNGGVLKESTPRETRFFGGRLYCLENAIKTDFSIVKAWKGDRCGNLVFRGTARNFNVPVGQCGQTVIAEVENLVENGDIDPDEVHLPGVYVDRVVVPERYQTLIEHRTVTRHDGAGNKPTKASTRGEEVRQRIARRAALEFANGMYVNLGIGIPTESSNYIPAGVNVVLQSENGLIGMGPFPTEDKVDADWINAGKQTISHLAGSALFDSATSFAMIRGGHMDLTMLGALEVAANGDLANFMIPGKLVKGPGGAMDLVSCGTRVVVTTTHCSKNGDPKIVERCRLPVTGKHCVCRIITEYAVFDVVDGRLVLKEIAEDTTVDQVKKLTGVGFDADNVITMPLAPLT
Protein: 4-hydroxybutyrate--CoA ligase 1 (EC 6.2.1.40) (Acetate--CoA ligase) (EC 6.2.1.1) (Butyrate--CoA ligase) (EC 6.2.1.2) (Propionate--CoA ligase) (EC 6.2.1.17) (A4YDT1)
Organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Function: Involved in the 3-hydroxypropionate/4-hydroxybutyrate cycle which incorporates carbon dioxide into cellular carbon. Catalyzes the ligation of coenzyme A (CoA) to 4-hydroxybutyrate (4HB). It can also use butyrate, valerate, propionate, acetate and 3-hydroxybutyrate (3HB) as substrates.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Vinylacetyl-CoA Delta-isomerase
- 4-hydroxybutyryl-CoA synthetase
- Succinate-semialdehyde dehydrogenase
- Acetyl-CoA acetyltransferase
- 3-hydroxyacyl-CoA dehydrogenase, NAD-binding protein
- CoA-binding domain protein
- Ala-tRNA
- 4-hydroxybutyrate--CoA ligase 2
- Citrate synthase
- Citrate synthase
Sequence:
MVTVQDFFRKFIEFQNSPNEKSLQEIVKLVGQLDLRRFNWVRDVFEDIHVKERGSKTALIWRDINTGEEAKLSYHELSLMSNRVLSTLRKHGLKKGDVVYLMTKVHPMHWAVFLAVIKGGFVMVPSATNLTVAEMKYRFSDLKPSAIISDSLRASVMEEALGSLKVEKFLIDGKRETWNSLEDESSNAEPEDTRGEDVIINYFTSGTTGMPKRVIHTAVSYPVGSITTASIVGVRESDLHLNLSATGWAKFAWSSFFSPLLVGATVVGINYEGKLDTRRYLGEVENLGVTSFCAPPTAWRQFITLDLDQFRFERLRSVVSAGEPLNPEVIKIWKDKFNLTIRDFYGQTETTAMVGNFPFLKVKPGSMGKPHPLYDIRLLDDEGKEITKPYEVGHITVKLNPRPIGLFLGYSDEKKNMESFREGYYYTGDKAYFDEEGYFYFVGRGDDVIKTSDYRVGPFEVESALLEHPAVAEAAVVGVPDTVRWQLVKAYIVLKKGYMPSKELAEEIREKMKTLLSPYKVPRIIEFVDELPKTISGKIRRVELRKREEEKRKKGEVGQNEYVF
Protein: RNA helicase (EC 3.6.4.13) (F6S4E6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATL
Protein: MADS-box transcription factor 16 (OsMADS16) (Protein APETALA3-like) (Protein SUPERWOMAN1) (Q944S9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor involved in the development of floral organs. Required for normal development of lodicules and stamens (whorls 2 and 3). May function as a heterodimer with MADS4.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MGRGKIEIKRIENATNRQVTYSKRRTGIMKKARELTVLCDAQVAIIMFSSTGKYHEFCSPSTDIKGIFDRYQQAIGTSLWIEQYENMQRTLSHLKDINRNLRTEIRQRMGEDLDGLEFDELRGLEQNVDAALKEVRHRKYHVITTQTETYKKKVKHSYEAYETLQQELGLREEPAFGFVDNTGGGWDGGAGAGAAADMFAFRVVPSQPNLHGMAYGGNHDLRLG
Protein: Manganese lipoxygenase (Mn-LO) (MnLOX) (EC 1.13.11.-) (EC 1.13.11.45) (Linoleate 11S-lipoxygenase) (Linoleate 13R-lipoxygenase) (Manganese 13R-lipoxygenase) (13R-MnLOX) (Q8X150)
Organism: Gaeumannomyces tritici (Wheat and barley take-all root rot fungus) (Gaeumannomyces graminis var. tritici)
Function: Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 11S- and 13R-hydroperoxy fatty acids. At the end of lipoxygenation, the intermediate product 11S-HPODE from linoleic acid is then transformed into 13R-HPODE as the final product. It also acts on alpha-linolenic acid producing 11S-HPOTrE and 13R-HPOTrE with subsequent transformation of 11S-HPOTrE to 13R-HPOTrE as the final product. Gamma-linolenic acid is a poor substrate. Oleate and arachidonate are not substrates.
Subcellular location: Secreted {ECO:0000269|PubMed:12047377, ECO:0000269|PubMed:9582345}.
Interaction partners:
Sequence:
MRSRILAIVFAARHVAALPLAAEDAAATLSLTSSASSTTVLPSPTQYTLPNNDPNQGARNASIARKRELFLYGPSTLGQTTFYPTGELGNNISARDVLLWRQDAANQTATAYREANETFADITSRGGFKTLDDFALLYNGHWKESVPEGISKGMLSNYTSDLLFSMERLSSNPYVLKRLHPTKDKLPFSVESKVVKKLTATTLEALHKGGRLFLVDHSYQKKYTPQPGRYAAACQGLFYLDARSNQFLPLAIKTNVGADLTYTPLDDKNDWLLAKIMFNNNDLFYSQMYHVLFHTIPEIVHEAAFRTLSDRHPVMGVLNRLMYQAYAIRPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQGGGGFQAGYLEKDLRSRGLVGEDSGPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTYGADDGDDGALLRDYELQNWIAEANGPAQVRDFPAAPLRRRAQLVDVLTHVAWVTGGAHHVMNQGSPVKFSGVVPLHPAALYAPIPTTKGATGNGTRAGLLAWLPNERQAVEQVSLLARFNRAQVGDRKQTVRDAFAAPDLLAGNGPGYAAANARFVEDTGRISREMAGRGFDGKGLSQGMPFVWTALNPAVNPFFLSV
Protein: Probable LRR receptor-like serine/threonine-protein kinase At1g69990 (EC 2.7.11.1) (C0LGI5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKTISIFFVIILMSSSHAEDDVLCLKGFKSSLKDPSNQLNTWSFPNSSSSICKLTGVSCWNAKENRILSLQLQSMQLSGQIPESLKLCRSLQSLDLSFNDFSGLIPSQICSWLPYLVTLDLSGNKLSGSIPSQIVDCKFLNSLALNQNKLTGSIPSELTRLNRLQRLSLADNDLSGSIPSELSHYGEDGFRGNGGLCGKPLSNCGSFNGKNLTIIVTAGVIGAVGSLCVGFGMFWWFFIRDRRKMNNYGYGAGKCKDDSDWIGLLRSHKLVQVTLFQKPIVKIKLVDLIEATNGFDSGNIVVSSRSGVSYKADLPDGSTLEVKRLSSCCELSEKQFRSEINKLGQIRHPNLVPLLGFCVVEDEILLVYKHMANGTLYSQLQQWDIDWPTRVRVAVGAARGLAWLHHGCQPLYMHQYISSNVILLDEDFDARVIDYGLGKLVSSQDSKDSSFSNGKFGYVAPEYSSTMVASLSGDVYGFGIVLLEIVTGQKPVLINNGEEGFKESLVEWVSKHLSNGRSKDAIDRRIFGKGYDDEIMQVLRIACSCVVSRPKERPLMIQVYESLKNLGDQHGFFSEYSDEFPLIFNKQEHLK
Protein: E3 ISG15--protein ligase Herc6 (EC 2.3.2.-) (F2Z461)
Organism: Mus musculus (Mouse)
Function: Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:22272257}. Note=Exclusively cytoplasmic.
Interaction partners:
- Ubiquitin-like protein ISG15
- Ubl carboxyl-terminal hydrolase 18
- Ubiquitin/ISG15-conjugating enzyme E2 L6
- Interferon-induced protein 44
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- Antiviral innate immune response effector IFIT1
- Ubiquitin-like modifier-activating enzyme 7
- Interferon-induced helicase C domain-containing protein 1
- Antiviral innate immune response receptor RIG-I
- 2'-5'-oligoadenylate synthase-like protein 2
Sequence:
MYFSWAAGSRKPRRLKAGTSGIELLQAASGEHHSLLLFSNHRVYSCGDNSWGQLGQRRDQSTERPEPIQALNDLHVDLVSCGKEHSVAVCHKGKVFAWGAGSEGQLGIGEFKEISFMPTKIKALAGIKIIQVSCGHYHSLALSEDGHVFSWGRNSEGQLGLGKNSRSQAIPQKVKSLEGIPLAQVAAGGTHSFALSLTGTSFGWGSNRSGQLALSGNKVKEQIYKPHSIGALKNLSVIYISCGYEHTAVLTEEGQVFTFGGNSSGQLQPSPRSGQRGPQLIEGIGGRVSQIECASYHTIAYVYTTGQVVSLGRGPSHTSNPTHQEAPAENSDITCLLAAEDLVDIEVKDIFAGAHANFVTTRRVSHTRSTGVSMKILPEIIRINQSLVKKWRAANKRKDREGAKREISLIFSSSACLTASFLKKRDAGENNLIDVDLKLARDVFKKLTTEKWISSLITTCLEEYLLRDLPYSSPHQEALLVFLLLPECSIMQDPKNWKTLAFEFAKAIHKMGPQSLAFLRTCWASLEVSSLNILVQMLKKAIISQIQYGVATEQYITNIKVLLEVIKEVHKANCQLPESAFIINELSGIFNFDAEAGRMFIRHNDLDCTESSDMVVFSDFLFVFDLPSKIKLMKCDSFVKLMSEVMAFPEKMSSPPYLILKVRRSHLVEDTLRQLRQVEDFDLRKQLSVGFINEIRPEAGGVSSEFFHCIFEEMTDPKYEMFIYPEKGSSMWFPVNPKFEKSSYFLFGILCGLSLHNLKVINLPFPLALYKKLLNQKPSLEDLKELSLPLGRNLQEVLNCEAGDIEELHMYFSIYWDQKDVDLIPDGISVPVNETNKRDYVSKYVDYIFNISIKTIYEEFHRGFYKVCNWDIIRQFQPEELMTAIIGNATCDWKQFENNSKYKDGYDKSHPTILLFWKAFHDLTLDEKKKFLLFLTGCDRLHVKGLQNEGIVFRCSETFSEEDNPRSLTCHRMLDLPKYSSMRRMKEALQVAINNSTGFVSQE
Protein: GID complex associated protein 12 (Glucose-induced degradation protein 12) (Involved in actin patch formation protein 1) (Q12027)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- GID complex subunit 1
- GID complex subunit 5
- GID complex subunit 8
- GID complex substrate-recognition subunit 4
- GID complex subunit 9
- E3 ubiquitin-protein ligase RMD5
Sequence:
MATGRIQFAVSTPCNTKGKPSGYRLFEFKNDRLALVPSERGCTKVDVNANIQAFCYLRPNGRDTSISPDATHILDSCDYMVLAKSNGFIEIISNYQYKIKNGLRLAPSYILRCTPEDFESNFFSDYMIAGLEYSQGLLYCCMCSGRIYVFVMNLPTDYIQYKNMYNPMFPDCFFKVHHDNNTTHSSEEEKLFEGSTRYTGRSCSKHICYFLLPIEPSHLRSSPVVSSFCNMYQGLPIYRPSMYLHIERGISTFHINPLDRFCFMTVSPRSPLFIRKIILPLTYVTFLSTFISLKNSIQGDTCGEILSWDNVAQQNGFGSLFSWISNKFTFDTDIINSTIWDDIVKYSGTGMLDSGIVWKQRQGHAKDDIYELFHTQDMLGSSRRNSSFSTASSEPRPLSRRRRESFQALTRDAFRERMDVPCSTKWELDSFIRGLRRNTFMVDFEIVEKISHRNGNDGVNEDDNTTDESDETMTSFLTDNYKKMDIVCIDHFVTLSAFRPRYYDEPIIKIDSLSNKNGSENGTNEEEWAESQMKVDGQVIDDETAQFKQALGNLCSFKKLFMLDDSLCFILDTHGVLLINRFEIKNTKNLLRNSKDTIRIIPHDFGLINDTIVIINDIDVGTDNVCALTFHLVVTSMAGEITVLKGEFFKNCRLGRIKLCDSLKLNRKDRFVDKLALIDYDGLNAQKRRLDYDEKDLYTFIVKKVKRD
Protein: Citrate synthase (EC 2.3.3.16) (P14165)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Aconitate hydratase B
- Aconitate hydratase A
- Succinate--CoA ligase subunit beta
- Malate synthase G
- Fumarate hydratase class I
- 2-oxoglutarate dehydrogenase E1 component
- NAD-specific glutamate dehydrogenase
- Isocitrate dehydrogenase
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
- Probable malate:quinone oxidoreductase 1
Sequence:
MADKKAQLIIEGSAPVELPVLSGTMGPDVVDVRGLTATGHFTFDPGFMSTASCESKITYIDGDKGVLLHRGYPIEQLAEKSDYLETCYLLLNGELPTAAQKEQFVGTIKNHTMVHEQLKTFFNGFRRDAHPMAVMCGVIGALSAFYHDSLDINNPKHREVSAHRLIAKMPTIAAMVYKYSKGEPMMYPRNDLNYAENFLHMMFNTPCETKPISPVLAKAMDRIFILHADHEQNASTSTVRLAGSSGANPFACIASGIAALWGPAHGGANEAVLRMLDEIGDVSNIDKFVEKAKDKNDPFKLMGFGHRVYKNFDPRAKVMKQTCDEVLQELGINDPQLELAMKLEEIARHDPYFVERNLYPNVDFYSGIILKAIGIPTSMFTVIFALARTVGWISHWQEMLSGPYKIGRPRQLYTGHTQRDFTALKDRG
Protein: DnaJ heat shock protein family (Hsp40) member B12 (V9GYN7)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
Sequence:
XAVKRVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHRRVTDHLGVVYYVGDTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCSRLSEVQASLHG
Protein: Nucleoid-associated protein Rv3716c (P9WNR9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
Subcellular location: Cytoplasm, nucleoid {ECO:0000255|HAMAP-Rule:MF_00274}.
Interaction partners:
- Recombination protein RecR
- ATP-dependent Clp protease proteolytic subunit 2
- Hydrolase
- N-acetylmuramoyl-L-alanine amidase Rv3717
Sequence:
MQPGGDMSALLAQAQQMQQKLLEAQQQLANSEVHGQAGGGLVKVVVKGSGEVIGVTIDPKVVDPDDIETLQDLIVGAMRDASQQVTKMAQERLGALAGAMRPPAPPAAPPGAPGMPGMPGMPGAPGAPPVPGI