wanglab/gogpt-training-data huggingface dataset:
Protein: Calcium-activated potassium channel subunit beta-4 (BK channel subunit beta-4) (BKbeta4) (Calcium-activated potassium channel, subfamily M subunit beta-4) (Charybdotoxin receptor subunit beta-4) (K(VCA)beta-4) (Maxi K channel subunit beta-4) (Slo-beta-4) (Q9ESK8)
Organism: Rattus norvegicus (Rat)
Function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations (By similarity).
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Calcium-activated potassium channel subunit alpha-1
- Potassium channel subfamily U member 1
- Calcium-activated potassium channel subunit beta-1
- Small conductance calcium-activated potassium channel protein 3
- Small conductance calcium-activated potassium channel protein 1
- Intermediate conductance calcium-activated potassium channel protein 4
- Calcium-activated potassium channel subunit beta-2
- Small conductance calcium-activated potassium channel protein 2
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit alpha
Sequence:
MAKLRVSYEYTEAEDKSIRLGLFLIVSGILSLFIFGFCWLSPALQDLQATAANCTVLSVQQIGEVFECTFTCGTDCRGTSQYPCVQVYVNNSESNSRALLHSDQHQLLTNPKCSYIPPCKRENQKNSESVMNWQQYWKDEIGSQPFTCYFNQHQRPEDVLLQRTHDEIVLLHCFLWPVVAFVVGVLIVVLTICAKSLAVKAEAMKKRKFS
Protein: Uncharacterized TPR repeat-containing protein At1g05150 (O23052)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable inactive receptor kinase At2g26730
- Probable inactive receptor kinase At3g02880
- Probable inactive receptor kinase RLK902
- Probable inactive receptor kinase At5g16590
- Probable purine permease 18
- NADPH-dependent diflavin oxidoreductase 1
Sequence:
MATRGSRSEKVKRIFQQFDGNHDGGLNREEMAALVVAVNPRVKFSDEQINAILDEVFRTYAEFIDPNKGLTYDGLLRTYDDGAGDVDRDFDALGLELNADETTIKGSEAASSSSITDERAVEAQKKQRTAAWAVSPNHGIVFDETWKLVDDLEILVKRLKSKQEKDGKLKADNNNNNVDAFSDAGWSRELGPSSEISEKRIYWEESSHDYGVFVKELGVLRSKADGARSREEAFDGHMAIGRVLYEHQLFKEALVSFKRACELQPTDVRPHFKAGNCLYVLGKCKESKDEFLLALEAAESGGNQWAYLLPQIYVNLGIALEGEGMVLSACEYYREAAILCPTHFRALKLLGSALFGVGEYRAAVKALEEAIYLKPDYADAHCDLASSLHSMGEDERAIEVFQRAIDLKPGHVDALYNLGGLYMDLGRFQRASEMYTRVLTVWPNHWRAQLNKAVSLLGAGETEEAKRALKEALKLTNRVELHDAISHLKHLQKKKGKNNGNGNGGEGPFIVVEPSKFKTVGEKTTLRPDLATALQIRAFQRVTRLGKCDVEAVRKEMRDNDVPVSYSGSGGPTKSIRKPNLEEILRRLLSSLKPDTFQGAIKAINEKILALLDDSGSGRVDMGMFYAVIAPLCGGHSDKRKRVAFDALLWRPVNEGSSQITKTDAVKYIKLLRAIYIPSHGMSEMLEVHGEEEAESSVTVTFNQFLAMFDDPDWGFGIMSTILKLEANDRNRHGNQVCSVCRYPVIGSRFKEVKARFSLCNQCYGEGKVPPSFKQEEYKFREYESEAEAMKAKCVCFSMQSHKKAIAT
Protein: Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29) (P38876)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Peptidyl-tRNA hydrolase involved in the recycling of tRNA-Lys from diacetyl-lysyl-tRNA-Lys and is important for mitochondrial function.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Peptidyl-tRNA hydrolase 2
- Putative uncharacterized protein YOL114C
- Obg-like ATPase 1
- Glutamyl-tRNA
Sequence:
MSGKWRLVLTGIGNPEPQYAGTRHNVGLYMLELLRKRLGLQGRTYSPVPNTGGKVHYIEDEHCTILRSDGQYMNLSGEQVCKVWARYAKYQARHVVIHDELSVACGKVQLRAPSTSIRGHNGLRSLLKCSGGRVPFAKLAIGIGREPGSRSRDPASVSRWVLGALTPQELQTLLTQSEPAAWRALTQYIS
Protein: Outer dynein arm-docking complex subunit 3 (Coiled-coil domain-containing protein 151) (Q8BSN3)
Organism: Mus musculus (Mouse)
Function: Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (By similarity). May be required for motile cilia function.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:24067530}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:24067530}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:24067530}. Note=Enriched at centrioles in IMCD3 dividing cells. {ECO:0000269|PubMed:24067530}.
Interaction partners:
- Outer dynein arm-docking complex subunit 1
- Outer dynein arm-docking complex subunit 4
- Outer dynein arm-docking complex subunit 2
- Calaxin
- Thioredoxin domain-containing protein 3
- Dynein axonemal intermediate chain 2
- Dynein axonemal intermediate chain 1
- Dynein axonemal assembly factor 19
- Dynein axonemal heavy chain 5
- Coiled-coil domain-containing protein 39
Sequence:
MTSPLCWAAATTTVTSPEQAPAPSSKAKGSKVHRSKSMGRAQAWPAHHPKSATSFHAMKSSVHAQVLELQRKIQLLEGDRKAFYESSQWNMKKNQDTINQLQEETKALHVQLKDLLQGDSKVIQAIIQEWKSEKPFLKNRTCEQALEHLEHQLREKMNQLNALRHQVILRQKRLEDLRLQHSLRQLEMAEVQDSNMEAAKTMRNLENRLEKARMKAEEAEHITNVYLQLKSYLQEESLNLESRLDSMEAEVMNTKHEVQELKVVNQEAINARDIAKNQLQYLEESAIRDRKKREHYITDCKKRAEEKKLQTERMERKTHRDHVLLQSEDTIQDHQRHREEELRQRWSMYQMEVMFGKVKDATGVAESHAVVRRFLAQDETFTQLENLKKDNELALAKLKEEKQRLQRELENLKYSGDATLVSQRRLHEEMQKTFKKEEQRHNDVHERLEHTSRILQLVKDCLEHLANKLSHVKLDDTVLAGKKLDRDSEDYAYNLLVVVQEKLLKLQDQLESQDVPELLRHIADREFLATLEGKLPLYNTRILLPVASVKDKFFDEEESEDDDRDVVTRAAFKLRSQKLIEARSKKRNRLRRS
Protein: GH23305p (Mf2 protein) (Myofilin, isoform C) (Myofilin, isoform Q) (Q8I062)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFKNHLEMIGRNESPSKKAKFWQSYIRSLKGSEDIRAHEAPRASRPYSSYLDSPSYRSIYDEPATANERVQSSGYRYLPVSRDTYGYSPRAIYDHHYSRTIPANYDAEKAWNDHLKRMQEIERRYPSRYGLYLRDKPLTPNSLVPLEYEPEDKLLAELNKGKDIKDIF
Protein: MLO-like protein 2 (AtMlo2) (Q9SXB6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity).
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Arabidiol synthase
- Oleosin 20.3 kDa
- AT3G21215 protein
- Putative syntaxin-24
- At5g10750)
- Callose synthase 12
Sequence:
MADQVKERTLEETSTWAVAVVCFVLLFISIVLEHSIHKIGTWFKKKHKQALFEALEKVKAELMLLGFISLLLTIGQTPISNICISQKVASTMHPCSAAEEAKKYGKKDAGKKDDGDGDKPGRRLLLELAESYIHRRSLATKGYDKCAEKGKVAFVSAYGIHQLHIFIFVLAVVHVVYCIVTYAFGKIKMRTWKSWEEETKTIEYQYSNDPERFRFARDTSFGRRHLNFWSKTRVTLWIVCFFRQFFGSVTKVDYLALRHGFIMAHFAPGNESRFDFRKYIQRSLEKDFKTVVEISPVIWFVAVLFLLTNSYGLRSYLWLPFIPLVVILIVGTKLEVIITKLGLRIQEKGDVVRGAPVVQPGDDLFWFGKPRFILFLIHLVLFTNAFQLAFFAWSTYEFNLNNCFHESTADVVIRLVVGAVVQILCSYVTLPLYALVTQMGSKMKPTVFNDRVATALKKWHHTAKNETKHGRHSGSNTPFSSRPTTPTHGSSPIHLLHNFNNRSVENYPSSPSPRYSGHGHHEHQFWDPESQHQEAETSTHHSLAHESSEPVLASVELPPIRTSKSLRDFSFKK
Protein: Insulin-like growth factor-binding protein complex acid labile subunit (ALS) (P70389)
Organism: Mus musculus (Mouse)
Function: May have an important role in regulating the access of circulating IGFs to the tissues.
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Insulin-like growth factor-binding protein 3
- Insulin-like growth factor 1
- Insulin-like growth factor-binding protein 5
- Insulin-like growth factor 2
Sequence:
MALRTGSPALVVLLAFWVALGPCYLQGTDPGASADAEGPQCPVTCTCSYDDYTDELSVFCSSRNLTQLPDGIPVSTRALWLDGNNLSSIPSAAFQNLSSLDFLNLQGSWLRSLEPQALLGLQNLYHLHLERNLLRSLAAGLFRHTPSLASLSLGNNLLGRLEEGLFRGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKLTYLQPALLCGLGELRELDLSRNALRSVKANVFIHLPRLQKLYLDRNLITAVAPRAFLGMKALRWLDLSHNRVAGLLEDTFPGLLGLHVLRLAHNAITSLRPRTFKDLHFLEELQLGHNRIRQLGEKTFEGLGQLEVLTLNDNQIHEVKVGAFFGLFNVAVMNLSGNCLRSLPEHVFQGLGRLHSLHLEHSCLGRIRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTANQLTHLPRQLFQGLGQLEYLLLSNNQLTMLSEDVLGPLQRAFWLDLSHNRLETPAEGLFSSLGRLRYLNLRNNSLQTFVPQPGLERLWLDANPWDCSCPLKALRDFALQNPGVVPRFVQTVCEGDDCQPVYTYNNITCAGPANVSGLDLRDISETLFVHC
Protein: Nuclear pore complex-interacting protein family member A3 (F8WFD2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAKICKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAAEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPPECLLTPLPPSALPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPKCVCSLPFHPQRMIISRN
Protein: DCAPL4 (Q966U8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MIHQTLAPHRSKSSSYSKSKAVHWRQKLHSSCNDLELEDEPYPAPQGMWHSQEINENPWQRPQSSGADGSSNNNVCDIPNCGKILWIHRREYDYNRSAPLRPPSPSNYHGVPSAVGYHVVGLPLTPQPNQRQAYLANQHAIGATMPLLLWQQQQQLLQQQRQHQQNLQQLQHRKYQDMQHRWPSNVNIHFKTPIRHEQRQNLSEEELAIRQAEHMQKLYHEERRRKYLQELQDMNSRRHTDNFTPSQKSPIALNRYDDFPTDVTLKSLVGPKTVARALFNFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPSKRPSEGQARAKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTSSEPLAYRALYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYVERA
Protein: DELLA protein SLR1 (Gibberellic acid-insensitive mutant protein) (OsGAI) (Protein SLENDER RICE1) (Q7G7J6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. In contrast, its overexpression prevents the GA signaling pathway and induces a dwarf phenotype.
Subcellular location: Nucleus {ECO:0000269|PubMed:10713441, ECO:0000269|PubMed:11826299, ECO:0000269|PubMed:24131983}.
Interaction partners:
- Gibberellin receptor GID1
- F-box protein GID2
- Protein SLENDER RICE1-LIKE 1
- Transcription factor APG
- Transcription factor PHYTOCHROME INTERACTING FACTOR-LIKE 15
- Os04g0618600 protein.
- Transcription factor PHYTOCHROME INTERACTING FACTOR-LIKE 13
- Helix-loop-helix DNA-binding domain containing protein, expressed
- Os01g0885250 protein
- Protein SLENDER RICE1-LIKE 2
Sequence:
MKREYQEAGGSSGGGSSADMGSCKDKVMAGAAGEEEDVDELLAALGYKVRSSDMADVAQKLEQLEMAMGMGGVSAPGAADDGFVSHLATDTVHYNPSDLSSWVESMLSELNAPLPPIPPAPPAARHASTSSTVTGGGGSGFFELPAAADSSSSTYALRPISLPVVATADPSAADSARDTKRMRTGGGSTSSSSSSSSSLGGGASRGSVVEAAPPATQGAAAANAPAVPVVVVDTQEAGIRLVHALLACAEAVQQENFAAAEALVKQIPTLAASQGGAMRKVAAYFGEALARRVYRFRPADSTLLDAAFADLLHAHFYESCPYLKFAHFTANQAILEAFAGCHRVHVVDFGIKQGMQWPALLQALALRPGGPPSFRLTGVGPPQPDETDALQQVGWKLAQFAHTIRVDFQYRGLVAATLADLEPFMLQPEGEADANEEPEVIAVNSVFELHRLLAQPGALEKVLGTVHAVRPRIVTVVEQEANHNSGSFLDRFTESLHYYSTMFDSLEGGSSGQAELSPPAAGGGGGTDQVMSEVYLGRQICNVVACEGAERTERHETLGQWRNRLGRAGFEPVHLGSNAYKQASTLLALFAGGDGYRVEEKEGCLTLGWHTRPLIATSAWRVAAA
Protein: Uncharacterized protein (Q9D927)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSLTSLALSLRSRRVVLASASPRRKEILGLTGVALEVVPPRFPETLSKAAWPRPQDYARETATGKAQEVAARLVQEDPETPTIVIGADTVVAVDGRILEKPKDREDALGDLRSLSGKQHQVITGVAIVTWGGCEGPAQEVTAFHEETSVTFSPLSEELIREYTDSGEGWDKAGAYAIQARGAMLVQDVAGDVLNAVGFPLNRFCRELARVPPTRTGSEEVTSQTTGIDSKDVK
Protein: Ferritin (EC 1.16.3.1) (B6DMH6)
Organism: Pseudo-nitzschia multiseries (Marine planktonic diatom) (Nitzschia pungens f. multiseries)
Interaction partners:
Sequence:
MKSPFFFLSALALTLRDSSPSFATAFRLAVTRCARQGIHAPSSSSSSSSRCLVASASALAGPSEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSFLGPCLFRSV
Protein: Neutrophil collagenase (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (O88766)
Organism: Rattus norvegicus (Rat)
Function: Can degrade fibrillar type I, II, and III collagens.
Subcellular location: Cytoplasmic granule. Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Stored in intracellular granules.
Interaction partners:
- Metalloproteinase inhibitor 1
- Metalloproteinase inhibitor 2
- Elastase, neutrophil expressed
- Matrilysin
- Metalloproteinase inhibitor 4
- Metalloproteinase inhibitor 3
- Alpha-2-macroglobulin
- Neutrophil gelatinase-associated lipocalin
- Myeloperoxidase
- Matrix metalloproteinase-9
Sequence:
MLHLKTLPFLFFFHTQLATALPVPPEHLEEKNMKTAENYLRKFYHLPSNQFRSARNATMIAEKLKEMQRFFGLPETGKPDAATIEIMEKPRCGVPDSGDFLLTPGSPKWTHTNLTYRIINHTPQMSKAEVKTEIEKAFKIWSVPSTLTFTETLEGEADINIAFVSRDHGDNSPFDGPNGILAHAFQPGRGIGGDAHFDSEETWTQDSKNYNLFLVAAHEFGHSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIYGPSDNPVQPTGPSTPTACDPHLRFDAATTLRGEIYFFKDKYFWRRHPQLRTVDLNFISLFWPFLPNGLQAAYEDFDRDLVFLFKGRQYWALSAYDLQQGYPRDISNYGFPRSVQAIDAAVSYNGKTYFFVNNQCWRYDNQRRSMDPGYPTSIASVFPGINCRIDAVFQQDSFFLFFSGPQYFAFNLVSRRVTRVARSNLWLNCP
Protein: Glucose-6-phosphate 1-dehydrogenase 2 (G6PD) (EC 1.1.1.49) (P97324)
Organism: Mus musculus (Mouse)
Function: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P11413}. Membrane {ECO:0000250|UniProtKB:P11413}; Peripheral membrane protein {ECO:0000250|UniProtKB:P11413}.
Interaction partners:
- 6-phosphogluconate dehydrogenase, decarboxylating
- 6-phosphogluconolactonase
- Glucose-6-phosphate isomerase
- GDH/6PGL endoplasmic bifunctional protein
- Cellular tumor antigen p53
- Hexokinase-3
- Hexokinase-2
- Glucose-6-phosphatase 3
- Glyceraldehyde-3-phosphate dehydrogenase
- Pyruvate kinase PKM
Sequence:
MAEQVTLSRTQVCGILREELYQNDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPKETFIVGYARSQLTVDDIQKQSEPFFKATPEERPKLEEFFTRNSYVVGQYDDPASYKHLNSYINALHQGMQANHLFYLALPPTVYEAVTKNIQETCMSQTGFNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLDKEMVQNLMVLRFANRIFGPIWNGDNIVCVILTFKEPFGTEGRGGYFDEFGIIRDVMQSHLLQMLCLVAMEKPATTDSDDVRNEKVKVLKCISEVETDNVILGQYVGNPNGEGEAANGYLDDPTVPRGSTTATFAAAVLYVKNERWDGVPFILRCGKALNERKAEVRLQFRDIPGDIFHQKCKRNELVIRMQPNEAVYTTMMTKKPGMFFNPEESELDLTYGNKYKNVKLPGAYERLILDVFCGCQMHFVRTDELREGWRIFTPLLHKIEREKPQPFPYVYGSRGPTEADELMRRVGFQYKGTYKGTHKH
Protein: Tyrosine protein-kinase src-2 (EC 2.7.10.2) (SRC oncogene related protein 2) (O45539)
Organism: Caenorhabditis elegans
Function: Non-receptor tyrosine-protein kinase which may play a role in larval and pharynx development. Unlike src-1, does not play a role in embryonic development.
Interaction partners:
- Sperm-Specific family, class R
- Ig-like domain-containing protein
Sequence:
MGSCIGKEDPPPGATSPVHTSSTLGRESLPSHPRIPSIGPIAASSSGNTIDKNQNISQSANFVALFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATGRTGYIPSNYVAREKSIESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVRENDSVKHYRIRQLDHGGYFIARRRPFATLHDLIAHYQREADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWNVNVPVAVKKLKAGTADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIVTELMQENLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDKRPTFETLQWKLEDLFNLDSSEYKEASINF
Protein: Anaerobic glycerol-3-phosphate dehydrogenase subunit A (G-3-P dehydrogenase) (EC 1.1.5.3) (P0A9C0)
Organism: Escherichia coli (strain K12)
Function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.
Subcellular location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase.
Interaction partners:
- Anaerobic glycerol-3-phosphate dehydrogenase subunit B
- Anaerobic glycerol-3-phosphate dehydrogenase subunit C
- Glycerol kinase
- Aerobic glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate transporter
- Glycerophosphodiester phosphodiesterase, periplasmic
- Glycerol uptake facilitator protein
- Glycerol-3-phosphate dehydrogenase [NAD
- Probable glycerol-3-phosphate acyltransferase
- Glycerol-3-phosphate acyltransferase
Sequence:
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
Protein: Biorientation defective 1, isoform B (Biorientation defective 1, isoform D) (Q8IMM6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDDFIKTLIAEVKSQGVFDEFRFNCCLADVDTKPAYQNVRTQVETAVNDFLAKQQWTPETNKVQLRERLRKHLMDSDVLDKGVDQIVDQVVNPKVATIFEPKIESIVYKYLGITPPARPTMLSAPPLPPFGAHLNGSSLLNVETTVGLLPTDLEQISPDSDRATVKSESRDDELPPGVDDEDTSPSYELVSERKTLAIKEELNNVSLNNSDSVNGVSQASQLSQVSSDSRLTMASSTESMVDSHQHTAAHNSGEPENICEEAQMPKFSENSWDASAGTGRSEGRQLHFDIKQDAITFEGTERKNSVSETTSTGLQILSIEDEIMSEVKANIDDANNASIESIAPEPVQVPAPPKVNPPPPPRPASPKVEPPPPAPPGVESPPGPQPPASPRFDPPPPHTIEPPPPPAPPTLVPPPPPAPPTIKPPPPPAPPTVEPPPPPPPAPPTVEPPPPPPPAPTKVEPPPPPAPAEVEPPPPPAPTELEPPPPPAPPKVELPPPPAPPKAEAAITPRRAKGSNGFITELAVTPKESETRDKPHNVNTDVKEDEQPATTEDKQDKPLELGLDAPKDAVSTASESTESPTSTSSQSKSHSKSRDKEKEKDRRHHRHSDDKHRRRSTDRDRDRSRDKSHSKHSSSSSSKHSSSNSSSSKHKSSSSKNDKSSSSSSSRSNRESSSSKRSGTTSSSRHESSSHKKHKSSSSSSRSERDKGKEKDKEREKDSQSRSHHSSSSSSSSSRRKDHDRGRDRDRNKSNTSGSAENKAIHDDHSESKEKYKQRRGSDSNDEGKPPSSGGPAKNSQPEDSAATMKSDAPVENANGTNGNSNGSTNGACDNVSGVVIVSDILQQSTSSFVELTAGSQSHDRAESSKHEPEDIDGKEADNQPEKTELEARQDECASQNEVPTVEPQTLADSVPDLPAKESMDTLEDEKVETNVEENKSEEESKPENPPEECVDEPAQVGDVEDPPQDADKPATPVPISNEQSDEFSADFVTHFEENTDEFRTRLQLINQLIEDRKNLLNRLSEDGTQEEAVDIRALRRSLSKRRRSSMQEQHRVERETTPPQPRSPSSSSTAGSPAKRLRQDEPKSSPTPSDASINSKENEALEKQEHDALSARRLSKKLCQQQRYTNDDLYKPRPILSQRSRRRGLDSIL
Protein: tRNA-specific adenosine deaminase subunit tad2 (EC 3.5.4.33) (tRNA-specific adenosine-34 deaminase subunit tad2) (O94642)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Deaminates adenosine-34 to inosine in many tRNAs.
Interaction partners:
- tRNA-specific adenosine deaminase subunit tad3
- tRNA
- Histone-lysine N-methyltransferase, H3 lysine-37 specific
- Putative tRNA pseudouridine synthase C16C4.06c
- tRNA
- General transcription and DNA repair factor IIH subunit tfb1
- 18S rRNA
- Multifunctional methyltransferase subunit trm112
- tRNA
- tRNA
Sequence:
MAGDSVKSAIIGIAGGPFSGKTQLCEQLLERLKSSAPSTFSKLIHLTSFLYPNSVDRYALSSYDIEAFKKVLSLISQGAEKICLPDGSCIKLPVDQNRIILIEGYYLLLPELLPYYTSKIFVYEDADTRLERCVLQRVKAEKGDLTKVLNDFVTLSKPAYDSSIHPTRENADIILPQKENIDTALLFVSQHLQDILAEMNKTSSSNTVKYDTQHETYMKLAHEMARTSLSNREVPVSCVFVYKGEVIGRGFNETNCSLSGIRHAELIAIEKILEHYPASVFKETTLYVTVEPCLMCAAALKQLHIKAVYFGCGNDRFGGCGSVFSINKDQSIDPSYPVYPGLFYSEAVMLMREFYVQENVKAPVPQSKKQRVLKREVKSLDLSRFK
Protein: Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) (Q9NSD5)
Organism: Homo sapiens (Human)
Function: Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA). Mediates transport of beta-alanine. Can also mediate transport of taurine and hypotaurine (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:22932902}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:P31649}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium- and chloride-dependent GABA transporter 3
- Putative protein CASTOR3P
- Gamma-aminobutyric acid receptor subunit delta
- Gamma-aminobutyric acid receptor subunit alpha-5
Sequence:
MDSRVSGTTSNGETKPVYPVMEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWERRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAEDLPQRNPAGPSAPATPRTSLLRLTELESHC
Protein: CHP-rich zinc finger protein-like (Cysteine/Histidine-rich C1 domain family protein) (Q9FJG5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Chaperone protein dnaJ 11, chloroplastic
- Early light-induced protein 2
Sequence:
MEEPKNIHPAALYTKGCRLAHPTHPHTLSPKLSKNTKSNCFTCGKQVSTSSRGFHYHCTICDVDFHEECVNIPRKILHPFHLQHPLFLTYGKHDNIIDGSNMSEQGPYEDQGTSDPGKSGWGNIFDNCTWCGKYIPTPSSHPRMTVFYRCSICNFCLDTMCTQTKPPLTIENPKGHHHSLVLFPRPLLVPCDACGLVNASEASYACFQCNYVVHQYCVDLPRVIKITRHPHRLSFSPYLPPPNSLCRVCYKTVDIKYGQYSCKDEDCSYVLHTKCATHVMVWDGKELEWEPEEPGVIEDIAPFKNVGDGLIEHFSHEHHLKLEKYDSVRDARKQCEACVLPIHLHDFYKCMQCDFFLHVVCACLPKKVDHALHNHSIILDPSPLPTDGNLQCSACSRTSTGFKYKCAEKNCKIHWFKIDVPCFLVPEYSIDKVHEHPLFIAPFNYDYEPFRCNGCKRGLTKNRLQCSTLCEYSICYECATIPSELHYKYDKHPLTLCYGEDTDDKYWCEECEKEVNTSEWFYTCNECCTTIHRNCLFGFHVYLKPGNTFKYHNRRMVEVLDNKSSTRPVCSRCEDRCQGSIYFKVDVRNVCASCLLKCL
Protein: ETS homologous factor (E9PN75)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVAESPDMKK
Protein: Tripartite motif-containing protein 16 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM16) (Estrogen-responsive B box protein) (Q99PP9)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin ligase that plays an essential role in the organization of autophagic response and ubiquitination upon lysosomal and phagosomal damages. Plays a role in the stress-induced biogenesis and degradation of protein aggresomes by regulating the p62-KEAP1-NRF2 signaling and particularly by modulating the ubiquitination levels and thus stability of NRF2. Acts as a scaffold protein and facilitates autophagic degradation of protein aggregates by interacting with p62/SQSTM, ATG16L1 and LC3B/MAP1LC3B. In turn, protects the cell against oxidative stress-induced cell death as a consequence of endomembrane damage.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O95361}.
Interaction partners:
- Galectin-3
- Vesicle-trafficking protein SEC22b
- Autophagy-related protein 16-1
- Galectin-8
- Beclin-1
- S-phase kinase-associated protein 1
Sequence:
MAELDLIAPGPLTGVTAHPLAPLGPDPVSAIPVEKEDADPLSKSGEETQEQGHDPAELGAPGEEDQILCDFCLGASRVRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPAKDQDLRTCPAHHSPLVSFCHTHQQCICQECGEGEHRGDSTVSLDAARRNKEVDLRCMQLDLEQKLKLNENAIARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQADVMVFLEEKEQAALNQVNSIKTHLEHRSLEMEKSKQELERLAAISNTVLFLEEYCKLKKTEDTASPSIYIGLKDKLSGIRKVITDSTLNLIQLLESYKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQEDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVELSGGGTYVGLTCKGIDRKGEERNSCISGNSFSWSIHWNGKEFTAWHSDTETPLKVSPFRRLGIYVNFPGGILSFYGVEYDAMTLIHKFDCKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAGSSVEAAP
Protein: Uncharacterized protein (Q57Z84)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Transmembrane protein
- Uncharacterized protein
- ATP synthase, epsilon chain, putative
- ATP synthase delta chain
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MSSGFHFHDVSNDAIKGMPPSEALHKHLENAQLAHRICLAKALKAGEPPVEKCALTWGEVLIRYQAWSEYRPPFQDSVAQAKYKKYWSKKRQEEDDKNPFK
Protein: Galactokinase (EC 2.7.1.6) (Galactose kinase) (Q9R0N0)
Organism: Mus musculus (Mouse)
Function: Catalyzes the transfer of a phosphate from ATP to alpha-D-galactose and participates in the first committed step in the catabolism of galactose.
Interaction partners:
- Galactose-1-phosphate uridylyltransferase
- Galactose mutarotase
- UDP-glucose 4-epimerase
- Interleukin-11 receptor subunit alpha-1
- Xylulose kinase
- Interleukin-11 receptor subunit alpha-2
Sequence:
MAAWRPPRVEELLAEARRAFMEEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELVTVMVGSPRTDGLVSLLTTSKDADEPQRLQFPLPSAQWSLEPGIPQWANYVKGVIQHYPASPLVGFSAVVVSSVPLGGGLSSSASLEVATYTFIQQLCPDSGAIAARAQVCQRAEHSFAGVPCGIMDQLIALLGQKGYALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLGSSEYPVRRRQCEEVAQALGKESLREVRMEELEAGRELMSKEGFRRARHVVSEIRRTAQAAAAMSRGDYKAFGRLMVESHYSLRDDYEVSCPELDQLVEAALSVPGVYGSRMTGGGFGGCTVTLLEASVAPLVIDHIQEQYSGTATFYLSQAADGAQVLSL