wanglab/gogpt-training-data huggingface dataset:
Protein: Protein YSY6 (P38374)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation (Potential).
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q9R2C1}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9R2C1}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9R2C1}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9R2C1}.
Interaction partners:
- ATPase GET3
- ER lumen protein-retaining receptor
- Protein FMP32, mitochondrial
Sequence:
MAVQTPRQRLANAKFNKNNEKYRKYGKKKEGKTEKTAPVISKTWLGILLFLLVGGGVLQLISYIL
Protein: Inactive hydroxysteroid dehydrogenase-like protein 1 (A5WWC6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:19026618}.
Interaction partners:
- Very-long-chain enoyl-CoA reductase
- Short-chain dehydrogenase/reductase family 42E member 1
- Dehydrogenase/reductase SDR family member 7C-A
Sequence:
MAAVDSFQLLYREIARSCSGYVETLALVGACYMASKTVIFMRDCYSLIRLYFVPRLVRHRDLSQQYGQWAIICGASEAIAKAYAEELARHGICVILISKDLSSVSDTARLISNNYGVEAICIEADFNQGPSACKPIKDAISSKDIGFLVNSFDGTLEISQNFLELSESVLWGTINRNIAATTLVTRLALPAMMEKGRGAVVNISSGHCFHPIPRKAAFSASTAFLDNFSRSLHYEYGDQGVFVQSLLPFRVASQRPEGSAPPASWLVPSPQVYASHALSTLGISHRTTGYWPHSMQLGLVKMMPEWVWMLGSRVFTMAT
Protein: THUMP domain containing 3 (H7C3J3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
XRNVKKEFTSHALDSHILDYYENPAIKEDVSTLIGDDLASCKDETDESSKEETEPQVLKFRVTCNRAGEKHCFTSNEAARDFGGAVQDYFKWKADMTNFDVEVLLNIHDNEVIVGIALTEESLHRRNITHFGPTTLRSTLAYGMLSKPSWGLPIDAVQWDICNLPLRTGSVDIIVTDLPFGKRMGSKKRNWNLYPACLREMSRVCTPTTGRAVLLTQDTKCFTKALSGMRHVWRKVDTVWVNVGGLRAAVYVLIRTPQAFVHPSEQDGE
Protein: 109 kDa U5 small nuclear ribonucleoprotein component GFL (Protein GFA1-LIKE) (SNU114 homolog) (F4JWP9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Splicing factor involved in pre-mRNA splicing and component of the spliceosome.
Subcellular location: Nucleus speckle {ECO:0000250|UniProtKB:Q9LNC5}.
Interaction partners:
- Pre-mRNA-processing-splicing factor 8B
- Protein STABILIZED1
- Pre-mRNA-processing-splicing factor 8A
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein E
- DExH-box ATP-dependent RNA helicase DExH13
- Tetratricopeptide repeat
- Small nuclear ribonucleoprotein SmD1a
- Small nuclear ribonucleoprotein-associated protein
Sequence:
MDGSLYGECGNYIGPEIESDRDSDDSVEDEDLQEPGGSNGWITTINENQNIVLPEDKKYYPIAKEVYGEDVETLVMDEDEQSLEQPIIKPVRDIRFEVGVIKDQTTTYVSTLFLIGLMSNPALVRNVALVGHLQHGKTVFMDMLVEQTHRMSTFNAENDKHMRYTDTRVDEQERNISIKAVPMSLVLEDSRSKSYLCNIMDTPGNVNFSDEMTASLRLADGAVFIVDAAQGVMVNTERAIRHAIQDHLPIVVVINKVDRLITELKLPPRDAYYKLRYTIEVINNHISAASTNAADLPLIDPAAGNVCFASGTAGWSFTLQSFARMYAKLHGVAMDVDKFASRLWGDVYYHPDTRVFNTSPPVGGGERAFVQFILEPLYKIYSQVIGEHKKSVETTLAELGVTLSNSAYKLNVRPLLRLACSSVFGSASGFTDMLVKHIPSPREAAARKVDHSYTGTKDSPIYESMVECDPSGPLMVNVTKLYPKSDTSVFDVFGRVYSGRLQTGQSVRVLGEGYSPEDEEDMTIKEVTKLWIYQARYRIPVSSAPPGSWVLIEGVDASIMKTATLCNASYDEDVYIFRALKFNTLPVVKTATEPLNPSELPKMVEGLRKISKSYPLAITKVEESGEHTILGTGELYLDSIIKDLRELYSEVQVKVADPVVSFCETVVESSSMKCFAETPNKKNKLTMIAEPLDRGLAEDIENGVVSIDWNRVQLGDFFRTKYDWDLLAARSIWAFGPDKQGTNILLDDTLPTEVDRNLMMGVKDSIVQGFQWGAREGPLCDEPIRNVKFKIVDARIAPEPLHRGSGQMIPTARRVAYSAFLMATPRLMEPVYYVEIQTPIDCVTAIYTVLSRRRGYVTSDVPQPGTPAYIVKAFLPVIESFGFETDLRYHTQGQAFCLSVFDHWAIVPGDPLDKAIQLRPLEPAPIQHLAREFMVKTRRRKGMSEDVSGNKFFDEAMMVELAQQTGDLHLQMI
Protein: BHLH transcription factor Mesp-a (Mesoderm posterior aa) (Q9IB70)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDASTFSLQLQNCSFFLPDSQNQSFAVSDAGYYSATGSLSPTSSIDSCSFSPPAYSLLPQIFPKSIQKTDVQPPKRTGRPKSKFPGVKRQTASEREKLRMRDLTKALHHLRTFLPASVAPVGKTLTKIETLRLAIQYISCLSDQLGCGEDVEICEAQDEVISTSASVFDNFSSASSASQSLPAQQFMSMSCYQTQNPVQGDFHSFPAQDVWFSQRHNFFHGQC
Protein: TLC domain-containing protein 4 (Transmembrane protein 56) (Q96MV1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MEINTKLLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSLVVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIGDKFFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAIVINGILMTVVFFIVRIASMLPHYGFMYSVYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKGCIKVISHIRQEKAKNSLQNGKLD
Protein: DiSHevelled related (H2KZ17)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAESPPPVDSSLNAPNVGSPTTMMERLRLRDQTEENGKEDDFDNKSVSSAQYSQTSEATTAVKQQPFLHTMTKVYCHIDDETDPYMLEVHVPPDLITLGDLKRVLMRTNFKYYRKALDPDSGYEVKAEIRDDSQRLTPSPNNLFELFLLTIEGSTHSDGSSGKMRKYPSVPGPAPSNRNGPPMNYQHAAYQFDNSMMSTDSESMISAAIPGYLKSAAYNRRFPQHYLGHRRHLEESTIGSESDARVFSDDDDRGSTTTDFTSVSRQHEKMAKKKKNKRNFRKPSRASSFSSITESSMSLDVITVNLNMDTVNFLGISIVGQTSNCGDNGIYVANIMKGGAVALDGRIEAGDMILQVNETSFENFTNDQAVDVLREAVSRRGPIKLTVAKSFENGQSCFTIPRNSREEPVRPIDTQAWIQHTNAMRGMPSIVEESAPTPIPGEWPHGRPPSSSTVTSNGSNGQNTVVGGGAHIILDIHTDKKKVVEIMAMPGSGLDIKNRTWLKIPIPMSFLGSDLVEWLLDHVEGLRERKTARNFAADLLKLKYIAHVVNKVTFTEQCYYVLGDECSDYARFRNEDGGPKYQWTIGMNGMSAGNGSSVMLPPPHLPGGMAGPPGAFKGMAPSMVSGYASMPASPFPPAQLQQQRREGSTTSGSSGGGIRKQRVVVLPRKPSSSANVPFDDSSTIYEESNNSFLMATGQRYEY
Protein: Glutathione hydrolase 2 (EC 3.4.19.13) (Gamma-glutamyltransferase 2) (Gamma-glutamyltranspeptidase 2) (EC 2.3.2.2) (Q680I5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be required for glutathione transport into developing seeds.
Subcellular location: Secreted, extracellular space, apoplast {ECO:0000269|PubMed:17316175}. Note=Associated with the plasma membrane and cell wall.
Interaction partners:
- 5-oxoprolinase 1
- Glutathione synthetase, chloroplastic
- Puromycin-sensitive aminopeptidase
- Gamma-glutamylcyclotransferase 2-2
- Gamma-glutamylcyclotransferase 2-3
- Leucine aminopeptidase 1
- Glutathione reductase, cytosolic
- 1-Cys peroxiredoxin PER1
- Leucine aminopeptidase 3, chloroplastic
- Leucine aminopeptidase 2, chloroplastic
Sequence:
MNSFMSLVRTATIALLLIAFLQNANAVKNLQSIVAYHGAVATDDGRCSAIGTNVLRQGGNAIDASVAAALCLGVVSPASSGIGGGAFTMIKLANGTEVAYDSRETAPLSATEDMYGDNPERKKKGSLSVGVPGEVAGLYTAWTQHGKLPWKQLVEPAEKLAAEGFKISKYLYMQMNATRSDILADKGLSELFVSNGELKKPGAICRNPKLADTLSQIAEYGPKAFYNGTVGFNLVSDIQKAGGIITLKDLQNYNVKVKEPLSTEILGYRLLGMPPPSSGGPAMMLILNILAQYGIPSGVSGPLGVHRLVEALKHAFAVRMNLGDPDFVPEVTNVVADMLSPKFAQDLKSKINDEKTFDPKYYGGKWGQIKDHGTSHLSIIDSERNAVSMTSTINGYFGAIMLSPSTGIVLNNEMDDFSIPTKSGGDPDVPPPAPANFIRPGKRPLSSMTPTIVLKDGKVKAALGASGGMYIIAGTTQVYLNHFFLNMDPLSSVVAPRIYHQLIPNKASYENWTTVYSDHFEIPEEIRLVLEKKGQVLTPIAGGTISQLIVEQSDGKSGGISKLVAVSDPRKGGFPSGY
Protein: Mitotic-spindle organizing protein 2B (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B) (Q6NZ67)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20360068}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:20360068}.
Interaction partners:
Sequence:
MAAQGVGPGPGSAAPPGLEAARQKLALRRKKVLSTEEMELYELAQAAGGAIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQDPAAVSLPTSSVPETRGRNKGSAALGGALALAERSSREGSSQRMPRQPSATRLPKGGGPGKSPTRGST
Protein: Hypocretin neuropeptide precursor (Hypocretin) (Hcrt) (Orexin precursor) (Prepro-orexin) (Preprohypocretin) [Cleaved into: Orexin-A (Hypocretin-1) (Hcrt1); Orexin-B (Hypocretin-2) (Hcrt2)] (O55241)
Organism: Mus musculus (Mouse)
Function: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.
Subcellular location: Rough endoplasmic reticulum {ECO:0000250|UniProtKB:O55232}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:O55232}. Synapse {ECO:0000250|UniProtKB:O55232}. Note=Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. {ECO:0000250|UniProtKB:O55232}.
Interaction partners:
- Orexin receptor type 2
- Orexin/Hypocretin receptor type 1
- Pro-MCH
- Leptin
- Oxytocin-neurophysin 1
- Pro-opiomelanocortin
- Pro-neuropeptide Y
- Appetite-regulating hormone
- Pro-thyrotropin-releasing hormone
- Oxidation resistance protein 1
Sequence:
MNFPSTKVPWAAVTLLLLLLLPPALLSLGVDAQPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLGKRRPGPPGLQGRLQRLLQANGNHAAGILTMGRRAGAELEPHPCSGRGCPTVTTTALAPRGGSGV
Protein: Siroheme decarboxylase NirH subunit (EC 4.1.1.111) (P95415)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in heme d1 biosynthesis. Catalyzes the decarboxylation of siroheme into didecarboxysiroheme (By similarity).
Interaction partners:
- Pre-heme d1 synthase
- Siroheme decarboxylase NirG subunit
- Dihydro-heme d1 dehydrogenase
- Cytochrome c55X
- Protein NirF
- Siroheme decarboxylase NirD subunit
- Siroheme decarboxylase NirL subunit
- Nitrite reductase
- Cytochrome c-551
- uroporphyrinogen-III C-methyltransferase
Sequence:
MSACISPSDALLARRLIELTQAGLPLVADPWAWIAAQLRLSEAETLALLKRLRDAGVIRRIAAVPNHYRLGYRHNGMTVWDVADERIERLGRLVGGLSFVSHCYRRPRHLPQWRYNLFAMVHGRSEAEIEGYRQQIRLLLGEDCRADEMLVSSRILKKTGLRLAQKEERPC
Protein: Cadherin-3 (Placental cadherin) (P-cadherin) (P22223)
Organism: Homo sapiens (Human)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Catenin beta-1
- Nephrin
- Catenin delta-1
- Cadherin-1
- Podocin
- Tight junction protein 1
- Catenin alpha-1
- Immunoglobulin kappa variable 1-33
- Cadherin-2
- CD2-associated protein
Sequence:
MGLPRGPLASLLLLQVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKVFMGCPGQEPALFSTDNDDFTVRNGETVQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVLGAVLALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD
Protein: Protein NRT1/ PTR FAMILY 5.16 (AtNPF5.16) (Q9SK96)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Chloride channel protein CLC-b
- Leucine-rich repeat
Sequence:
MAIAEEEAALIEDSVSDSVDHRGLPAGKSSTGGWRSAWYIIGVEVGERFAYFGIGSNLITYLTGPLGQSTATAAVNVNTWSGTASILPVLGAFIADAYLGRYRTIVVASLIYILGLGLLTLSSILILMGLSEQRQHNRNASAKPFFWVNILFFCSLYLVAIGQGGHKPCVQAFGADQFDVGDPKERISRGSFFNWWFLSLSAGITLSIIVVVYVQDNVNWALGFGIPCLFMVMALALFLFGRKTYRYPRGDREGKNNAFARIGRVFLVAFKNRKLKLTHSGQLEVGSYKKCKGQLEFLAKALLPGEGGVEPCSSRDVEDAMALVRLIPIWITSVVSTIPYAQYATFFTKQGVTVDRKILPGFEIPPASFQALIGLSIFISVPTYERVFLPLARLITKKPSGITMLQRIGAGMVLSSLNMVVAALVEMKRLETAKEHGLVDRPDATIPMSIWWFVPQYLLLGMIDVFSLVGTQEFFYDQVPTELRSIGLALSLSAMGLASFLSGFLITVINWATGKNGGDSWFNTNLNRAHVDYFYWLLAAFTAIGFLAFLLLSRLYVYRRVDQV
Protein: Split discs, isoform G (X2J9Z8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTSLAAVPQASATGSSSNSNINNNNALAALQDGGAAAAAAADFYQQLAAAATATATATSANGSNTSADSPVSSFPAAAAAVAVAAVAASSYQQQQQQQQLLNNEQQQQQLLEANNKMQELHKQMERFRSEQMQLETRITELLPYQSEVAKLKGDLVKMQSLQEKSQMEIGNLKYENESLRNRLRDVVNSPLSDAEKHQIIQDSQRLHSSAPASIALPSTHDAHDGTPCLTPDWDKQSSSSEISVACLQDKIIQMEETHYSTNEELQATLQELADLQTQLTDTQTENERLAEEKDVLFQSLCRQTEKLNESRTQISTLQELLLRDTKQPAPEVSASEREQKLLDLIKTSQEEREAVLLKQEELGAELAEMKQAREAGQLELQRQRERIALLDSQLDAANAERRQGEAQFSQAMEEISQRAIEISRLSTLLENARSKIEELEADLSRGDKTDLSEVLDVARKEKDALEERVAELQDQCSRSQAELRRLRDQLSGLTEECKVVKNNAKCAVSHLEYRLEQLQRDKDKIAGEWQALEERVAELQVQCKCHQEDKAQLQSLLAETQRHLGDVQLKLGEAECRLDQETQLRRKEAEEWQQFQADLLMTVRVANDFKTEALSAREQLVLDNKTQKEKIRLLEQQLEKLTKQQMQQSETPQSVLSTVQREMEMATRRSKLSFSRQDSRLSVKTLIESIENNKAQGKADESESHYSSTSSLNSGTPDLGTTPIIFPPSSDWHESIRLPVLQSTNLHVNVGNEVGAGQGTNTSSGSGGDLASTTKATLPLRDQQQLAITSTQSQVQNVSQPSTPATPSSAGSSSSGGLPFGNVSKSFISGERKDPLNMLAKNGGSKRNALLKWCQNKTVGYRNIDITNFSSSWNDGLAFCAILHSYLPDRIPYDQLTPANKRRNFSLAFAAAESVGIGTTLVHICTYMLQPKETQTRWQMWK
Protein: Nuclear export mediator factor (A0A8I6A2E1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MKTRFSTVDLRAVLAELNANLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYLILNILRFRTDEADDVKFAVRERYPIDHARAAEPLLTLERLTEVIARAPRGELLKRVLNPLLPYGPALIEHCLIENGFSGNVKVDEKLESKDIEKILVCVQRAEDYLEKTANFNGKGYIIQKREVKPSLDANKPAEDILTYEEFHPFLFSQHLQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGVIVKEAQAQGDPVASAIKELKLQTNHITMLLRNPYLLSEEEDGDGDGSIENSDAEAPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQRTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGDPIPPRTLTEAGTMALCYSAAWDARVITSAWWVHHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHRGERKVRVQDEDMETLTSCTSELMSEEMEQLEGGDSSEEETEELRGTTEEVELRTQADPEDIAAHSGREELSSEDGEAIKTATKDEEPIGEVREEEEEPFEYPDTTIDLSHLQSQRPLQKLTPREESFNSSDSKSQSRRHLSAKERREMKKKKLPCDSGDLEVIEEKDKEKESAVHSEADQNTSKNVAAGQPMKRGQKSKMKKMKEKYKDQDDEDRELIMKLLASAGSNKEEKGKKGKKGKTKDEPVKKNPQKPRGGQRVLDVVKETPSLQASTPDLQDFAVDEPHDDKEEHDLDQQGNEENLFDSLTGQPHPEDVLMFAIPICAPYTIMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLHVKRK
Protein: Endoplasmic reticulum-resident calcium binding protein (PfERC) (Pf39) (Pfs40) (Q8IIR7)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:23061985, ECO:0000269|PubMed:32098818, ECO:0000269|PubMed:9364972, ECO:0000269|PubMed:9497061}.
Interaction partners:
Sequence:
MMKINLYKLLCFICVIFLLHKNVVRSGDNMKYNDMKGLDDLSKLNDDQVKDILGLKIDGAKERIEKLFHLIDKNNDKEITEEELNTWSSFLKNEIFLKQVQAEMGQIDSDKDGFISLNELNDAFAQNLDAKEVEKHSEGLLKRFQIVDKDKDGKLSINEVGLLIDPMKDEELKELEINEILEHHDVNKDGKISLDEFKQTRSDESSGVKKDDEMALDDFNFFDANKDGFIDKEEIIKVYFDPAHESGAINVNEIKENIFEGKKITYDLWNEKALKIAVTSLTDYGDVIRYPEDFKLDIGKNVILPTARSRAFEDDDMDADNTEDDKDEADDASQQKSPAIDEL
Protein: Glutamate racemase (EC 5.1.1.3) (Q9ZLT0)
Organism: Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Function: Provides the (R)-glutamate required for cell wall biosynthesis.
Interaction partners:
Sequence:
MKIGVFDSGVGGFSVLKSLLKARLFDEIIYYGDSARVPYGTKDPTTIKQFGLEALDFFKPHEIELLIVACNTASALALEEMQKYSKIPIVGVIEPSILAIKRQVEDKNAPILVLGTKATIQSNAYDNALKQQGYLNISHLATSLFVPLIEESILEGELLETCMHYYFTPLEILPEVIILGCTHFPLIAQKIEGYFMGHFALPTPPLLIHSGDAIVEYLQQKYALKNNACTFPKVEFHASGDVIWLERQAKEWLKL
Protein: Rho GTPase-activating protein 44 (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2) (F1LQX4)
Organism: Rattus norvegicus (Rat)
Function: GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. Acts as a GAP at least for CDC42 and RAC1. In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity. Limits the initiation of exploratory dendritic filopodia. Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces. Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation. In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation (By similarity).
Subcellular location: Cell projection, dendritic spine {ECO:0000269|PubMed:23739967, ECO:0000269|PubMed:25498153}. Recycling endosome {ECO:0000250|UniProtKB:Q5SSM3}. Presynapse {ECO:0000269|PubMed:23739967}. Cell projection, dendrite {ECO:0000269|PubMed:25498153}. Note=In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites (By similarity). Located in convoluted dendritic plasma membrane sections enriched in polymerized actin and myosin (patches) along dendrites where often emerge filopodia (PubMed:25498153). {ECO:0000250|UniProtKB:Q5SSM3, ECO:0000269|PubMed:25498153}.
Interaction partners:
- Cdc42-interacting protein 4
- SH3 and multiple ankyrin repeat domains protein 3
Sequence:
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDELAQELIHFELRVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLMISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNIQEQDKRLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQSEGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGSYGSPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTSWVARRGSSAGRKAACAPPSMQPPAPPSELAAPLPSPLPEQVPDSPATPAPALSPSGASLQPTPERPSVSKSKELSPGSGQKGSPGSIQGTTCPGTQLGPQPAASPSQLPADQSPHTLRKVSKKLAPIPPKVPFVQPGTVSDQPTGQPSPVSLSPTPPSTPSPYGLSYPPGYSMASGQLSPASAPPLASPSVFTSTLAKSRPTPKPRQRPTLPPPQPPSVSLSASSPQSTEHPMLDGMSPGESMSTDLVHFDVPSIHIELGSTLRLSPLEHARRHSVTDKRDSEEESESTAL
Protein: Solute carrier family 16 member 3 (J3KTM6)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGGAVVDEGPTGVKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
Protein: Alginate regulatory protein AlgR3 (Q500P4)
Organism: Pseudomonas syringae pv. syringae (strain B728a)
Interaction partners:
Sequence:
MSAKKKPVNTPLHLLQQLSGSLLEHLEDACSQALADAEKLLAKLEKQRGKAQEKLHNSRIKLQDAATAGKSKAQAKAKGAVSELEELLDALKDRQTETRTYILHLKRDAQESLKLAQGIGRVKEAVGKILTTRDAKPVAPKAVAKTPAAKAPAKTAAKAPVKTAAAKPVAKAAAKPSAAAKPAAKTAVAKAPVKAAAKPAPRATAAAKPVAAKTTAAKPAAARTTAAKPAAAKPAATKAPVAKTTASNAAKPAAAKAAAAKAPVKAPVKAPAKAPAKAPVKAAAKPVAKPAAKPAVKPAAAKPATPAPAAAKPTTPAPAAPAAAPATPANGATPTSAS
Protein: MIP05887p (Seminal fluid protein 78E) (C0PPK1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNIFISLILVVLAILSFADHTVADGDRHLNEDLNRATVKKTKYGWQCAGVTCPIKFTASCKVTKVLKPSDLQHTELLILCMDKNDKPMCGITRTRKGVIQEVLDVDENGNTIYDKKEVISENDGTKIPRCPRK
Protein: SLC51 subunit beta (D3ZYJ2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Solute carrier family 51 member A
- Ileal sodium/bile acid cotransporter
- Bile salt export pump
- Hepatic sodium/bile acid cotransporter
- Cytochrome P450 7A1
- Bile acid receptor
- Nuclear receptor subfamily 0 group B member 2
- Cytochrome P450 family 8 subfamily B member 1
- Fibroblast growth factor
- Gastrotropin
Sequence:
MDHSAEGAAASAEVPQELLEEMLWYFRSEDATPWNYSILVLAVLVMVIGVVLLRRSILANRNRKKQPQDNGMPEDLHLDDSMKENSSLGILRETLISEKADLAPGETELNKRETSVVFLPDPQETES
Protein: Nuclear egress protein 1 (F5HFZ4)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Plays an essential role in virion nuclear egress, the first step of virion release from infected cell. Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2. Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space. There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
Subcellular location: Host nucleus inner membrane {ECO:0000255|HAMAP-Rule:MF_04023}. Note=Remains attached to the nucleus inner membrane through interaction with NEC2. {ECO:0000255|HAMAP-Rule:MF_04023}.
Interaction partners:
Sequence:
MSSVSGVRTPRERRSALRSLLRKRRQRELASKVASTVNGATSANNHGEPPSPADARPRLTLHDLHDIFREHPELELKYLNMMKMAITGKESICLPFNFHSHRQHTCLDISPYGNEQVSRIACTSCEDNRILPTASDAMVAFINQTSNIMKNRNFYYGFCKSSELLKLSTNQPPIFQIYYLLHAANHDIVPFMHAENGRLHMHVIFENSDVHIPCDCITQMLTAAREDYSVTLNIVRDHVVISVLCHAVSASSVKIDVTILQRKIDEMDIPNDVSESFERYKELIQELCQSSGNNLYEEATSSYAIRSPLTASPLHVVSTNGCGPSSSSQSTPPHLHPPSQATQPHHYSHHQSQSQQHHHRPQSPPPPLFLNSIRAP
Protein: Pleckstrin homology domain-containing family J member 1 (PH domain-containing family J member 1) (Guanine nucleotide-releasing protein x) (Q9NW61)
Organism: Homo sapiens (Human)
Interaction partners:
- Sesquipedalian-1
- Sesquipedalian-2
- Inositol polyphosphate 5-phosphatase OCRL
Sequence:
MRYNEKELQALSRQPAEMAAELGMRGPKKGSVLKRRLVKLVVNFLFYFRTDEAEPVGALLLERCRVVREEPGTFSISFIEDPERKYHFECSSEEQCQEWMEALRRASYEFMRRSLIFYRNEIRKVTGKDPLEQFGISEEARFQLSGLQA
Protein: DnaJ homolog subfamily C member 15 (Cell growth-inhibiting gene 22 protein) (Methylation-controlled J protein) (MCJ) (Q9Y5T4)
Organism: Homo sapiens (Human)
Function: Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:23263864, ECO:0000269|PubMed:23530063}; Single-pass membrane protein {ECO:0000269|PubMed:23263864, ECO:0000269|PubMed:23530063}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM16
- Mitochondrial import inner membrane translocase subunit TIM44
- Stress-70 protein, mitochondrial
- Mitochondrial import inner membrane translocase subunit Tim17-A
- Mitochondrial import inner membrane translocase subunit Tim17-B
- GrpE protein homolog 1, mitochondrial
- Mitochondrial import inner membrane translocase subunit Tim23
- Mitochondrial import inner membrane translocase subunit Tim21
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit TIM14
Sequence:
MAARGVIAPVGESLRYAEYLQPSAKRPDADVDQQRLVRSLIAVGLGVAALAFAGRYAFRIWKPLEQVITETAKKISTPSFSSYYKGGFEQKMSRREAGLILGVSPSAGKAKIRTAHRRVMILNHPDKGGSPYVAAKINEAKDLLETTTKH
Protein: UL37 (Q89815)
Organism: bovine alphaherpesvirus 1
Interaction partners:
Sequence:
MSGDPVRALWAALERLDGEVAGPAALAEARAAVSEFLLASGPSSLDFVAPRWAALQRAACRAYERLHTPDAALLAENLPGLVLWRLPGAARDTADFMAGVRDLANSMIAEAPLGYLAAARLRATAAFGPVNMQRVVVEWASLFLEIYAREDAACVGVLGPDPACRSPAGSAAVIRPLLQSRFRLLYDMPFFQAGLSALAHAANWKVPMAAVARRAADAAAPPLARALFAVALVDEYFPEPDDEDTAPGLAEAFAEIADLVPPEALVPAGEANAFARSSHDVRVSAALAYRDPFVRGAAAGSVAARVRADAGLLADDTLLGRDAVAVHAGAVVRLLERAAARATPAALGRVAEHAAAVWDAVQASATPDQAVETLAAAGFTPGTCAMLERAVLAQLSRPEPRAPADVLQAVGCVAVAGGVLFKLFDAYGPSADYLAHYTATIANLHPYYADVLPLLGLPDGGLEQTIRHCMAPRPRTDYVAAIRAALAAEAAAADKRAASASARAAVENSGDRAAAGAAAREALLTWFDLRASERWGVAPPAAEAPPAAEAARSPAAGGASAAELARAARALEFPRTDAVPAAVLRDPAFAPHFAAAVLSDVLVAADALPFSANGVAQLMALIAWARDCGAGAVANVDGYRTKLSALAAGLWPFVDASAPAPTTTQVRNAEAVLGELHTVATTAAECLPPEVRPPVPARPRVGGCVFLASMYLHAAFARLQGYVAETEALAASMAAAVGDVAGAVARLGVLFDCHFASVPGQQMLAIYATRGAPCALGAWRSADLADAVRGARAEAARARAEVRVSLAALQRAAAQTTQALQECEAADARPPGGGLDDEHRALLAGHSALVRAQTALALAAGKLVAGAEAPGLHEVGRFLQRWDAIGAALGRALDDSAGERDVAELVARLRGVWDEVQEDRRVAAPGPPRSAANAAAAEEAVLALLEGYPEVRGDEGSPALLDARADVADWAGVDRGPLQRRASAGADAAASAAAANTAAGPWLTTEDLLAEVDGVCASRPAAAR