wanglab/gogpt-training-data huggingface dataset:
Protein: Ubp5-interacting protein ftp105 (Down-regulated in multiple cancers 1 homolog 3) (Hid-1 family protein ftp105) (O13776)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the localization of ubp5 to the Golgi apparatus. Involved in detoxification of cadmium ion.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi apparatus {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:20838651}.
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 5
- UBP9-binding protein bun107
- Ubp4-interactor sfp47
- UBP9-binding protein bun62
- Ubiquitin carboxyl-terminal hydrolase 11
- Ubiquitin thioesterase otu2
- Probable ubiquitin carboxyl-terminal hydrolase 16
Sequence:
MGGQESKLAFQRGIARLASQPDIPLDDEVWVSLWSVPESCPEVYDFFPPGLIREMRDHAFVNLEKLLLVLTSRLFALKNDKKFPNPETAPASEALNCIRLLTRIIPFLNEKLDLEEWHQKFWWSLRKKRNLPKENSELDLSNFQDDLDFENSISQKNEFSQKSPSVPLSPVSTFPASSISLDASSDVSAADVSVGGSSTIKEIGSIEETFTHEKTLMEELLDTVFRLLFCRGFTLPLSSPEQYAYIIWENGIGTTETQEKTTKELAFNRIEVLRLLLVLISKRLYRSSEVASHTLTYLTCVANKQLILVFLYSLINTTLRLRPDSWKASYSTLVPYNDSSIALSKLTSQILLLFLDHTPHETTVEYFRQRLNLSPGAAIENQYRLYFSRLQLQADYEFLVNELYRLLNAPVSAISAYISIVQKPNIAFPEIILFLWQAILYNKRFRAFLITSPYATEFLTSIQFYALRYREDNEHSGLVRICLFIVHYLSCEKVLCEKLNRNCMNAQSLMSSLGFSVPPMSYAEFLIISSFHISAVKRSPFSSLSPVILLTICNIAPFVENLSFVTCAKLMQLCSSLSSPRFLFRNPRNHLLLEYLLQAISSIVENKFSQNPNLSYSIIRLQQVFLNLNSMKLPAVAQTKSQPLVALNSEGSSDFESKSSDNTSLDGTPLQNTDFKKVATVEDDSPFDELDKFSSPFSSSSSRGGLSHISSRNVSISVPTVLQDVFSDSPLVLSRKLRGKIPENVSSSELIKKCASNPFGKDLEIDSNLFAPSNSWFNSWHSRLELDSILAIISQFSLPVYKKMNEELSTTDEAVKLLANSVLNDVHPRVPNFRYFIWSVPMNNWFQSLVWLYTLSFDEKGLMATPSLFTTSKVYKQHGNIMKVASPENSSNSMENATKSILDKLDLLYLQLPSSVNHDSSLRNK
Protein: PAX4 protein (Q3KNR5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MAWSSKSWLCLIASSCPRDTLLPSAHHASPVPASHLTQVSNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISAQGPTVFMSRKY
Protein: Probable multidrug resistance protein EmrY (P52600)
Organism: Escherichia coli (strain K12)
Function: Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- Probable multidrug resistance protein EmrK
- Multidrug export protein EmrA
- Outer membrane protein TolC
- Acetyl-CoA:oxalate CoA-transferase
- Uncharacterized transporter YfdV
- Formyl-CoA:oxalate CoA-transferase
- Probable aminoglycoside efflux pump
- Multidrug resistance protein MdtB
- HTH-type transcriptional regulator YdeO
- Multidrug efflux pump subunit AcrA
Sequence:
MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSLSTNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWESTSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSSSQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTAKGVG
Protein: 1-acylglycerol-3-phosphate O-acyltransferase Pnpla3 (EC 2.3.1.51) (Acylglycerol transacylase) (Adiponutrin) (ADPN) (Calcium-independent phospholipase A2-epsilon) (iPLA2-epsilon) (EC 3.1.1.4) (Lysophosphatidic acid acyltransferase) (Patatin-like phospholipase domain-containing protein 3) (EC 3.1.1.3) (Q91WW7)
Organism: Mus musculus (Mouse)
Function: Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides (By similarity). In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety (By similarity). However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity (By similarity).
Subcellular location: Membrane {ECO:0000269|PubMed:11431482, ECO:0000269|PubMed:22560221}; Single-pass membrane protein {ECO:0000269|PubMed:11431482}. Lipid droplet {ECO:0000269|PubMed:22560221}.
Interaction partners:
- Diacylglycerol O-acyltransferase 2
- Diacylglycerol O-acyltransferase 1
- Lipoprotein lipase
- Monoglyceride lipase
- Hepatic triacylglycerol lipase
- 2-acylglycerol O-acyltransferase 1
- Endothelial lipase
- Pancreatic lipase-related protein 2
- 2-acylglycerol O-acyltransferase 2
- Pancreatic triacylglycerol lipase
Sequence:
MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTRSRASKDDHRMLKHGHHPSPHKPQGNSAGL
Protein: Uroporphyrinogen decarboxylase (EC 4.1.1.37) (A0A1B0GVZ4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Protein: Ras homolog family member T1 (A0A0G2K777)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004200}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004200}.
Interaction partners:
- Trafficking kinesin protein 1
- Trafficking kinesin-binding protein 2
- Kinesin-1 heavy chain
- Unconventional myosin-XIX
- Kinesin heavy chain isoform 5A
- Mitofusin-2
- E3 ubiquitin-protein ligase parkin
- Mitochondrial import receptor subunit TOM20 homolog
- Serine/threonine-protein kinase PINK1, mitochondrial
- Syntaphilin
Sequence:
MRAGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNESGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIVCDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSVSPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRGSLSRDMGSTDRIENLRKIWVFLKTAFHARLRCMCTCNRCTFCICQNLLNSDLLQSVKNKVFTAVLNRLKARVAEWGAMLLADDEGSITHQVHAVRSVEDSIFMESSRGQIFLDNRHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR
Protein: Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45) (Q8K387)
Organism: Mus musculus (Mouse)
Function: Catalyzes the deubiquitination of SPDL1 (By similarity). Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites (By similarity). May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development (By similarity). Plays a role in cell migration (By similarity).
Subcellular location: Photoreceptor inner segment {ECO:0000250|UniProtKB:Q70EL2}. Cytoplasm {ECO:0000250|UniProtKB:Q70EL2}. Nucleus {ECO:0000250|UniProtKB:Q70EL2}.
Interaction partners:
- DNA excision repair protein ERCC-1
Sequence:
MRVKDPSKDLPEKGKRNKRPLLPHDEDSSDDIAVGLTCQHVSYAVSVNHVKKAVAESLWSVCSECLKERRFCDGQPVLPADVWLCLKCGLQGCGKNSESQHSLRHFKSSGTESHCVVISLSTWVIWCYECNEKLSTHCNKKVLAQIVDFLQKHAFKTQTGAFSRIIKLCEEKREAGEIKKGKKGCTVPSVKGITNLGNTCFFNAVIQNLAQTYILFELMNEIKEDGTKFKISLSSAPQLEPLVVELSSPGPLTSALFLFLHSMKEAEKGPLSPKVLFNQLCQKAPRFKGFQQQDSQELLHHLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTMKDPFIDISLPIIEERVSKPVLLGKMSKCRSLQETDQDHNKGTVTVGNAHQPRASRKHSSPNDKNQLSHDRKHLRKWPSEEEKTVVTHPKNDNLEASPPASTLSTEASLNESLTDGSERDASLESSVDADSEASEPEIASKQPVLLRSRGDSCGHAEQHPHLPLASELPQAKETHGGEEEMAEAIAELHLSGTVTGNRDFHREKQPLNVPNNLCFSEGKHTRLHSAQNAFQTLSQSYVTTSKECSVQSCLYQFTSMELLMGNNKLLCEDCTEKRRKCHKETSSAEKKAGGVYTNARKQLLISAVPAILILHLKRFHQAGLSLRKVNRHVDFPLTLDLAPFCAATCKNISVGEKVLYGLYGIVEHSGSMRGGHYTAYVKVRVPSRKLSECITGRKTAAGLKEPDGELGGHWVHVSDTYVQVVPESRALSAQAYLLFYERIL
Protein: RE60377p (Stem cell tumor, isoform A (EC 3.4.21.-)) (Q9W0F1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSGKRTRSFKCAVHHRDREVCSENDFQLVLNEPPLFRKMVHAVAMEILPEERDRKYYADRYTCCPPPFFIILVTLVELGFFVYHSVVTGEAAPRGPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQMRYGVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNIMNGFAMFNIRVEKIRVTETIFNDFQV
Protein: Nitric oxide reductase QnorB (A1JHG0)
Organism: Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
Interaction partners:
Sequence:
IWLVLMMRGILPALRARGTDRNLLALLTSSVVAIGLFYGAGLAYGERTSLTVMEYWRWWVVHLWVEGFFEVFATTALAFIFSTLGLVSRPMATAASLASASLFMLGGIPGTFHHLYFAGTTTPVMAVGAAFSALEVVPLIVLGHEAWENWSLKRRAPWMADLKWPLMCFVAVAFWNMLGAGVFGF
Protein: Dynactin subunit 5 (Q9N4I1)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Dynactin subunit 6
- Dynactin subunit 4
- Actin-related protein 10
- Probable dynactin subunit 2
- Dynactin subunit 1
- DyNactin Complex component
- Actin
- F-actin-capping protein subunit beta
- F-actin-capping protein subunit alpha
- Protein sumv-1
Sequence:
MDLPIVYYDETEWAKTHTGNKVNKKHAIAGTQNILIAGKTIIEEGVTIRGDLATVKIGKYCVLKSRCNIRPCMKIFSKKPTMCNVMIGDYVFIEEECVVNAAQIYAFVHLGARAVLGNGCVIRECSRVLPDTVVPADALFPPYSTIGGNPAQVVGTEPRCTENLMMEAITMYYDNFVPKQRAIA
Protein: Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (Q69FE3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR038189}.
Interaction partners:
Sequence:
MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS
Protein: LIM domain binding 3 (A0A0G2JYM0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, myofibril, sarcomere, Z line {ECO:0000256|ARBA:ARBA00004216}.
Interaction partners:
Sequence:
MGAARADISVDSILSQLFLGALHSLTRQQGTQQARPEEATAVGTSMSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPIQSPLPVIPHQKVVANSPANADYQERFNPSVLKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGASPLASLPVKDLAVDSASPVYQAVIKTQSKPEDEADEWARRSSNLQSRSFRILAQMTGTEYMQDPDEEALRRSSTPIEHAPVCTSQATSPLLPASAPSPAAASPIAASPTLATAAAAHAVAASAAGPASSPVENPRPQASAYSPAAATSPAPAAHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASPYSPSPGANYSPTPYTPSPAPAYTPSPAPTYTPSPAPTYSPSPAPAYTPSPAPNYNPTPSAAYSGGPSESASRPPWVTDDSFSQKFAPGKSTTSVSKQTLPRGAPAYNPTGPQVTPLARGTFQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFNCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPICAKCNTKIMGEVMHALRQTWHTTCFICAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLCKKHAHAINV
Protein: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (Alpha 2,3-ST 1) (Beta-galactoside alpha-2,3-sialyltransferase 1) (EC 2.4.3.4) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (Monosialoganglioside sialyltransferase) (EC 2.4.3.2) (ST3Gal I) (ST3GalI) (ST3GalA.1) (ST3O) (Sialyltransferase 4A) (SIAT4-A) (P54751)
Organism: Mus musculus (Mouse)
Function: A beta-galactoside alpha2-3 sialyltransferase involved in terminal sialylation of glycoproteins and glycolipids. Catalyzes the transfer of sialic acid (N-acetyl-neuraminic acid; Neu5Ac) from the nucleotide sugar donor CMP-Neu5Ac onto acceptor Galbeta-(1->3)-GalNAc-terminated glycoconjugates through an alpha2-3 linkage. Adds sialic acid to the core 1 O-glycan, Galbeta-(1->3)-GalNAc-O-Ser/Thr, which is a major structure of mucin-type O-glycans. As part of a homeostatic mechanism that regulates CD8-positive T cell numbers, sialylates core 1 O-glycans of T cell glycoproteins, SPN/CD43 and PTPRC/CD45. Prevents premature apoptosis of thymic CD8-positive T cells prior to peripheral emigration, whereas in the secondary lymphoid organs controls the survival of CD8-positive memory T cells generated following a successful immune response. Transfers sialic acid to asialofetuin, presumably onto Galbeta-(1->3)-GalNAc-O-Ser. Sialylates GM1a, GA1 and GD1b gangliosides to form GD1a, GM1b and GT1b, respectively.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q11201}; Single-pass type II membrane protein {ECO:0000255}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q11201}; Single-pass type II membrane protein {ECO:0000255}. Secreted. Note=Membrane-bound form in medial and trans cisternae of Golgi (By similarity). Secreted into the body fluid. {ECO:0000250|UniProtKB:Q11201}.
Interaction partners:
- Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
- Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
- C1GALT1-specific chaperone 1
- Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4
- Galactoside alpha-
- Beta-1,3-galactosyltransferase 4
- Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
- Beta-1,3-galactosyltransferase 5
- Galactoside alpha-
- Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Sequence:
MRRKTLKYLTFFLLFIFLTSFVLNYSNTGVPSAWFPKQMLLELSENFRRFIKSQPCTCRHCISQDKVSYWFDQRFNKTMQPLLTVHNALMEEDTYRWWLRLQRERKPNNLSDTVKELFRLVPGNVDPMLNKRLVGCRRCAVVGNSGNLKDSSYGPEIDSHDFVLRMNKAPTVGFEADVGSRTTHHLVYPESFRELGENVNMVLVPFKTTDLQWVISATTTGTITHTYVPVPPKIKVKQEKILIYHPAFIKYVFDNWLQGHGRYPSTGILSIIFSIHICDEVDLYGFGADSKGNWHHYWENNPSAGAFRKTGVHDGDFEYNITTTLAAINKIRIFKGR
Protein: Ferritin-3, chloroplastic (EC 1.16.3.1) (Q9LYN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
Subcellular location: Plastid, chloroplast {ECO:0000250}.
Interaction partners:
- CDGSH iron-sulfur domain-containing protein NEET
- Thioredoxin domain-containing protein PLP3B
- Metal-nicotianamine transporter YSL3
- Probable nicotianamine synthase 4
- At3g56360
- Metal transporter Nramp4
Sequence:
MLLKAASTFSLLNIHGEKKDISPLFSSSSSISSPVSSGKSGNLSFPLRASKSSTTTTSTLSGVVFEPFEEVKKEMDLVPSGQQLSLARHLYSPECEAAVNEQINVEYNVSYVYHALYAYFDRDNVALKGLAKFFKESSVEEREHAELLMEYQNKRGGRVKLQPMVLPQSEFDHPEKGDALYAMELALSLEKLVNEKLLNLHSVASKNDDVQLADFIESVFLNEQVEAIKKISEYVSQLRRLGKGHGTWHFDQELLGAAA
Protein: Large ribosomal subunit protein uL24 (60S ribosomal protein L26) (P61254)
Organism: Homo sapiens (Human)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23636399}.
Interaction partners:
- Small ribosomal subunit protein eS8
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL43
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein uL2
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL23
Sequence:
MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE
Protein: SEC24 homolog D, COPII coat complex component (Sec24 related gene family, member D (S. cerevisiae)) (Q6NXL1)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004397}.
Interaction partners:
- Protein SEC13 homolog
- Protein transport protein Sec16A
- Protein transport protein Sec31A
- Protein transport protein Sec31B
- Protein transport protein Sec23A
- Protein transport protein Sec23B
- Protein transport protein Sec24A
- SEC24 homolog B, COPII coat complex component)
- SEC24 homolog C, COPII coat complex component
- Protein transport protein Sec16B
Sequence:
MSQQGYVATPPYSQSQPGMGISPPHYGHYGDPSHASSPPGVMKPLGPSAAPSGMLPPGPLPPGPPQFGPNGAHTPGHPPQRFPGPPPVNSVAPSYASGQTLPQSSYPGPGSTSSVTQLGSQFSSMQINSYGVGATPQSQGPPGPQSAGAFQGPPQPAQPSILQPGHQVPPPPPTALNGPGASPMSPPTHRQDGLPGPAPLNAQYQPPPPPGQTLGPGYPPQQATNYGPQMGGAQMSYPGGFPGGPAQMAGPAPQLQRKLDPDSIPSPIQVIENDRATRGGQVYTTNTRGQVPPLVTTECVIQDQGHSSPRYIRCTTYCFPCTSDMAKQAQIPLAAVIKPFADIPPNETPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCSCVNEVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPSPPAFIFMIDVSYSNIKNGLVKLICEELKTALKRLPKEEHEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYEESQSVIHNLLDQIPEMFADSNENETVFAPVIQAGMEALKAAECPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTAVYESLAKDCVANSCSVTLFLFPSQFVDVASLGLVPLLTGGTLYKYNVFQIHSDSQRFLTDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDVGALIQCAVLYTTISGQRRLRIHNLALNCSTQLADLYKSCETDALINFFAKSAFKAVLNQPLKAIREILVNQTAHMLACYRKHCASPSAASQLILPDSMKVLPVYMNSLLKNCVLLSRSEISPDERAYQRQLVMTMGVADSQLFFYPLLLPIHTLDVKSAALPPAVRCSESRLSEEGIFLLANGLNMFLWFGVGSPPELIQGIFNVPSFAHINTDMTSLPEVGSPHSQQLRMIMNNIQQKKPYSMKLIVVKQREQREMAFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN
Protein: Replication protein A1 (F7FI87)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
TIKCLLDAGLNPALPEGKDQQEAAVLHFLGHAQQQAVSAPASAATPPASKPQPQNGSLGVGSTVAKAYGASKPFGKPAGTGLLQPTSGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSIELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGTLKIANKQFSAVKNDYEMTFNNETSVLPCEDGHHLPTVQFDF
Protein: F-box protein DAS1 (DST1-delta 6-azauracil sensitivity protein 1) (P47005)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity).
Interaction partners:
- Suppressor of kinetochore protein 1
- Cell division control protein 53
- COMPASS component SWD1
- COMPASS component BRE2
- Histone-lysine N-methyltransferase, H3 lysine-4 specific
Sequence:
MPFQDYFQKKKAAFINRNNKSNADASALRDINDININFAAKSKNYVFPLTKLPDELMQEVFSHLPQPDRLQLCLVNKRLNKIATKLLYRRIYLNDSNVVKSDFMHLAINWTLLNLPSSLKEEESRDIANCKLKKLIETLQNNIHITEVIQWIRINWDLDSTLQRSILSILCNQGKSLQRLENVTDPACNDIISNGHFSRSNVSSFDMAPPNSLPEMVVPENYIPNLTKYLSQRISSRLSHMTLFIDPLKLFNYLYPLDIKLQIIDLKLHWRREFYNNDYFVKKIRPGNPLTKLSEVFDKRTLKILTIISWNDTLLKRETEMLKDFKEFENLEDLSLISIKQDVHILVDLFSSLTNLKRLKMDFLEEYVPEPTNPHIFLSILLACSKLQFIDLRYDGLIPQIINIQENKFQLNQQCNCTNCQIVFSDILKGKIFMFPEDYYIHDLQDIAAKDIFKMMKYLSLLPYSKACDAYPSVRTQPMNLTNFVTKMNRNLLEYRNSKSQLVPKIVNNPHQHSTVTSTSTAHMSEPEMIIIDDDDDDDEINAAIPPSSDDTAATISTDLELPHESLTKRDIIMCYHALIHHFKSIYVTFLKSFPHLRFLMLNDIPTIVMEENNERIFEPVFYHYDYKSNLYGWSKESNKNLENDSNNNNNNSDTIARIATVM
Protein: Leucine-rich repeat protein (LRRP), putative (Q580F0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVVPVMNMTREPAVDSPENSRKISLAGYPEVAGLFCVTVFKSTLDLEVRDCCGLLTLDGVGKCVELKKFSISNCGMLTNISDLKDCVNLEMLTLSGCKTLRNLTPLKGHRTLSCITISHCERMMELDLEGATNLMQLNISDCEELKDVHVSRCTRLEVIDIHDCVKLEKLHGLTYLRELKTLILAGNRELSAVEGINELINRVEKLSLKNCEKLEDLKFLDFCNFLKEVVVAGSNVTEEKKQELRGKGVRIVNEVKVADG
Protein: GH14252p (Mf3 protein) (Myofilin, isoform D) (RH68506p) (Q95U15)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFKNHLEMIGRNESPSKKAKFWQSYIRSLKGSEDIRAHEAPRASRPYSSYLDSPSYRSIYDEPATANERVQSSGYRYLPVSRDTYGYSPRAIYDHHYSRTIPANYDAEKAWNDHLKRMQEIERRYPSRYGLYLRDKPLTPNSLVPLEYEPEDKLLAELNKARRSASPFRPARTTRAGSEPYVPPPSYWNREGSVPRGGPSVFDRATSLAPFTRPSFRASSLEPLDELFERLPIFHPRNRFRDLLSPSPNLPISSIVRDPFWWDVDDLVPFRATSVPRASSPVARDSYLSPVKNRYLWSKHPARPLTPHRSIL
Protein: Uncharacterized protein (Q389J7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSTVRTGGVCVKTEAKTNGPRTGLEDVHRFTLSVEETQRAEERRRVEASKRLLLSTDGGLIPNSCGGPSSQERSRFGSSIAEALRLRSETRERVLLQRILRQRREEEGNEELAEKDMEVGVFITPQYLSALKRQRSTRATSPGGLAKQTENTEDMDPLELYVQELEERRRVVGKKDHDSSDVGTNRNDGGRDQDMGLRVHSAQVVSGNKQPEHVERSGVTGIPCGHDVVYSVKASSGAWVPTGTNGAVIDVSGAAAPASPSPTANSATPQEALQEVRWRRQKPRADRSFIESAATRFNRRSMDRFV
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q86U11)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
ELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVFSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
Protein: Large ribosomal RNA subunit accumulation protein YCED homolog 1, chloroplastic (23S rRNA accumulation protein YCED) (Protein DUF177A) (Q9LT27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in synthesis, processing and/or stability of 23S rRNA. Required for embryogenesis.
Subcellular location: Plastid, chloroplast stroma, chloroplast nucleoid {ECO:0000269|PubMed:27574185}.
Interaction partners:
- Large ribosomal RNA subunit accumulation protein YCED homolog 2, chloroplastic
- Large ribosomal subunit protein bL35c
- Transcription termination factor MTERF8, chloroplastic
- Pre-mRNA-processing-splicing factor 8A
Sequence:
MSLVCSLSCVAPLPQTKQSRPSFLKLETCTLSLSSPAGYPNFTTGIRKHISYLFTEPIKLPRLAKSRILVSQESFTETSTIDMDWEDQEEIEDTGSPWEGSVMYRRNASVTHVEYCTTLERLGLGRLSTDVSKKRASAMGLRVTKDVKDYPDGTPVQVSVDVIRKKKKLRLDGIVRTVITLGCNRCGESTGESIFSNFSLLLTEEPVEEPDVIDLGFTFGNDKEEGEDDDDNDDSWIDWEDKLHFPPEVKEIDISKHIRDLVHLEITITAICDSACKGMCLKCGANLNKRKCDCGREEKDKGYGPLGNLREQMQQKEGLRN