wanglab/gogpt-training-data huggingface dataset:
Protein: Alcohol dehydrogenase 1C (EC 1.1.1.1) (Alcohol dehydrogenase subunit gamma) (P00326)
Organism: Homo sapiens (Human)
Function: Alcohol dehydrogenase. Exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism.
Subcellular location: Cytoplasm.
Interaction partners:
- Aldehyde dehydrogenase, mitochondrial
- All-trans-retinol dehydrogenase [NAD
- Alcohol dehydrogenase 1A
- Cytochrome P450 2E1
- Vasopressin-neurophysin 2-copeptin
- Amine oxidase [flavin-containing] A
- Aldehyde oxidase
- Amine oxidase [flavin-containing] B
- Catechol O-methyltransferase
- Cytochrome P450 26A1
Sequence:
MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLTF
Protein: Semaphorin-3B (Sema A(V)) (Semaphorin-V) (Sema V) (Q13214)
Organism: Homo sapiens (Human)
Function: Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Subcellular location: Secreted {ECO:0000250}. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum.
Interaction partners:
- Neuropilin-1
- Neuropilin-2
- Plexin-A3
- Plexin-A4
- Plexin-A2
- Plexin-A1
- Plexin-B1
- Plexin-C1
- Plexin-B3
- Plexin-D1
Sequence:
MGRAGAAAVIPGLALLWAVGLGSAAPSPPRLRLSFQELQAWHGLQTFSLERTCCYQALLVDEERGRLFVGAENHVASLNLDNISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEHKVFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPLRRLSLHVLSATQAERLARAEEAAPAAPPGPKLWYRDFLQLVEPGGGGSANSLRMCRPQPALQSLPLESRRKGRNRRTHAPEPRAERGPRSATHW
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (A0A0S2Z4B5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
Protein: GH21853p (Q961I4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMGGGGGVAGAGFSAGASGPMLGAGGHMLMGGQGHQVHLQHQTLLPVKMDKLVPNYDNAEHQMKFYDIRSPLVLSCNVKDGTPGGVLIWKKNGTAVTDVPSLRGRFKLIADENKFIIDKTDTNDDGKYSCEFDGVSKEIEVIARVVVRVPSNTAVVEGEKMSVTCSVVGTKPELTWTFANVTLTNATDRFILKPDDNGVPNAILTLDNVTLDDRGEYKCIGRNAANVYGGNTTTPASDVTTVRVKGKFAALWPFLGICAEVLILCIIILIYEKRRNKSELEESDTDPQEQKKKRRNYD
Protein: AP2-like ethylene-responsive transcription factor PLT2 (Protein AINTEGUMENTA-LIKE 4) (Protein PLETHORA 2) (Q5YGP7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366, ECO:0000269|PubMed:15454085}.
Interaction partners:
- Probable polyol transporter 3
- Serine/threonine-protein kinase BSK
- TIC-like protein
- Protein TIME FOR COFFEE
- E3 ubiquitin-protein ligase makorin
- Auxin efflux carrier component 1
Sequence:
MNSNNWLAFPLSPTHSSLPPHIHSSQNSHFNLGLVNDNIDNPFQNQGWNMINPHGGGGEGGEVPKVADFLGVSKSGDHHTDHNLVPYNDIHQTNASDYYFQTNSLLPTVVTCASNAPNNYELQESAHNLQSLTLSMGSTGAAAAEVATVKASPAETSADNSSSTTNTSGGAIVEATPRRTLETFGQRTSIYRGVTRHRWTGRYEAHLWDNSCRREGQSRKGRQVYLGGYDKEEKAARAYDLAALKYWGPSTTTNFPITNYEKEVEEMKNMTRQEFVASIRRKSSGFSRGASMYRGVTRHHQHGRWQARIGRVAGNKDLYLGTFSTEEEAAEAYDIAAIKFRGLNAVTNFEINRYDVKAILESNTLPIGGGAAKRLKEAQALESSRKREEMIALGSNFHQYGAASGSSSVASSSRLQLQPYPLSIQQPFEHLHHHQPLLTLQNNNDISQYHDSFSYIQTQLHLHQQQTNNYLQSSSHTSQLYNAYLQSNPGLLHGFVSDNNNTSGFLGNNGIGIGSSSTVGSSAEEEFPAVKVDYDMPPSGGATGYGGWNSGESAQGSNPGGVFTMWNE
Protein: Uncharacterized protein CXorf38 (Q8TB03)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVLSELAARLNCAEYKNWVKAGHCLLLLRSCLQGFVGREVLSFHRGLLAAAPGLGPRAVCRGGSRCSPRARQFQPQCQVCAEWKREILRHHVNRNGDVHWGNCRPGRWPVDAWEVAKAFMPRGLADKQGPEECDAVALLSLINSCDHFVVDRKKVTEVIKCRNEIMHSSEMKVSSTWLRDFQMKIQNFLNEFKNIPEIVAVYSRIEQLLTSDWAVHIPEEDQRDGCECEMGTYLSESQVNEIEMQLLKEKLQEIYLQAEEQEVLPEELSNRLEVVKEFLRNNEDLRNGLTEDMQKLDSLCLHQKLDSQEPGRQTPDRKA
Protein: Eukaryotic translation initiation factor 4E, putative (Q585M4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable eukaryotic initiation factor 4A
- Polyadenylate-binding protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
Sequence:
MQNLRADAVEYTPSWQKRSSAVAVTAPTPTTLPARATLPTPKTGFTTSMTSTNTITTHSGFSAQATTPQSPSCPPQGQQQQTVVPPPTRSPVSTHVIPTRMSPVHAPSAAFHMSPNAVSYVPRGAAAGSLMPLPTSTADLAVEKELQRKQQSGSPSTSSWVTTCTKSNGVRSATSPVPKAGSTPIVAEISVDKTDEEVLEISRCSSLKASAPAFLPRRTLNRSNMTKPSPFTLTPDSGDMRFGDPWCLFYLPVGGPDSTRESTYDPTLVFRMDCISSFWKVFNNIPEPTRMCAGTLYLFRDGINPKWEDLRNRDGGIVRAKVRPQVVDDAWLHLLCRTVGESWSRSVRNSVNGIALKVRAAAFMLEVWVTEQTSELMSDISELLHKFLGDAFQVPYIPHSVAQERAATNAAALAVKEKKNRGNRRLW
Protein: Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2) (Q6AXM8)
Organism: Rattus norvegicus (Rat)
Function: Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters.
Subcellular location: Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Serum paraoxonase/arylesterase 1
- Serum paraoxonase/lactonase 3
Sequence:
MGRLVALSLLGIGLALLGERFLALRSRLKASREVESVDLPNCRLIKGIETGAEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRALELRVSWGFDLASFNPHGISTFIDDDDTVYLFVVNHPEFKNTVEIFKFQEEENSLLHLKTIKHELLPSVNDVIAVGPSHFYATNDHYFSDPFLKYLETYLNLRWANVVYYSPEEVKLVAEGFDSANGINISPDKKYVYVADILAHEIHVLEKQPNMNLTQLKVLQLGTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNHPPSSEVLRIQNILSEKPSVTTVYINNGSVLQGSSVATIYDRKLLVGTLYQRALYCEL
Protein: Beta-parvin (Q9ES46)
Organism: Mus musculus (Mouse)
Function: Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration (By similarity).
Subcellular location: Cell junction, focal adhesion. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Cytoplasm, myofibril, sarcomere {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Constituent of focal adhesions. Detected at the tips of the leading edge of cells. Colocalizes with F-actin at the tips of lamellipodia (By similarity). {ECO:0000250}.
Interaction partners:
- LIM and senescent cell antigen-like-containing domain protein 1
- Scaffold protein ILK
- Paxillin
- Rho guanine nucleotide exchange factor 6
- Alpha-parvin
- Ras suppressor protein 1
- Alpha-actinin-1
- LIM and senescent cell antigen-like-containing domain protein 2
- Actin, cytoplasmic 1
- Gamma-parvin
Sequence:
MSSAPPRSPTPRAPKMKKDESFLGKLGGTLARKKKTREVTDLQEEGKSAINSPMAPALVDIHPEDTQLEENEERTMIDPTSREDPKFKELVKVLLDWINDVLAEERIIVKQLEEDLYDGQVLQKLLEKLAHCKLNVAEVTQSEIGQKQKLQTVLEAVQDLLRPHGWPLRWNVDSIHGKNLVAILHLLVSLAMHFRAPIHLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEIMMGRFERDAFDTLFDHAPDKLNLVKKSLITFVNKHLNKLNLEVTDLETQFADGVYLVLLLGLLEDYFVPLHNFYLTPDSFDQKVHNVAFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYTLFTKYKDVE
Protein: Histone-lysine N-methyltransferase Set2 (dSet2) (EC 2.1.1.359) (Q9VYD1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:17560546}. Chromosome {ECO:0000269|PubMed:17560546}. Note=Localizes to euchromatin. {ECO:0000269|PubMed:17560546}.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB1
- E3 ubiquitin-protein ligase Bre1
- Transcription elongation factor SPT6
- Histone H2A.v
- DNA-directed RNA polymerase II subunit RPB2
- Histone H3.3A
- Histone H3
- Histone-lysine N-methyltransferase SETD1
- Retinoblastoma-binding protein 5 homolog
Sequence:
MEESGPPSNPSPVASRGRGRGRPPKVALSALGNTPPHINPSLKHADAEASPTAPEDQDSGQSECRRSSRKKIIKFDVRDLLNKNRKAHKIQIEARIDSNPSTGHSQSGTTAASTSMSTATASAASASSAATVSRLFSMFEMSHQSLPPPPPPPTALEIFAKPRPTQSLIVAQVTSEPSAVGGAHPVQTMAGLPPVTPRKRGRPRKSQLADAAIIPTVIVPSCSDSDTNSTSTTTSNMSSDSGELPGFPIQKPKSKLRVSLKRLKLGGRLESSDSGNSPSSSSPEVEPPALQDENAMDERPKQEQNLSRMVDAEENSDSDSQIIFIEIETESPKGEEEQEEGRPVEVEPQDLIDIDMELAKQEPTPDPEEDLDEIMVEVLSGPPSLWSADDEAEEEEDATVQRATPPGKEPAADSCSSAPRRSRRSAPLSGSSRQGKTLEETFAEIAAESSKQILEAEESQDQEEQHILIDLIEDTLKSDNIAASLNKDIFEPKVETKATCGEVVPRPEMVTEDVYITEGIAATLEKSAVVTKPTTEMIAETKLSDEVVIEPPLKDESDPKQTEVELPESKPAVNIPKSERILSAEVETTSSPLVPPECCTLESVSGPVLLETSLSTEEKSNENVETTPLKTEAAKEDSPPAAPEEEASNSSEEPNFLLEDYESNQEQVAEDEMMKCNNQKGQKQTPLPEMKEPEKPVAETVSKKEKAMENPARSSPAIVDKKVRAGEMEKKVVKSTKGTVPEKKMDSKKSCAAVTPAKQKESGKSAKEAILKKETEKEKSSAKLDSSSPNTLDKKGKDTAQWSPQLQTLPKSSTKPPQESAPSVISKTTSNQPAPKEEQHAAKKGLSDNSPPSVLKAKEKAVSGFVECDAMFKAMDLANAQLRLDEKNKKKLKKVPTKVEAPPKVEPPTAVPVPGQKKSLSGKTSLRRNTVYEDSPNLERNSSPSSDSAQANTSAGKLKPSKVKKKINPRRSTICEAAKDLRSSSSSSTPTREVAASSPVSTSSDSSSKRNGSKRTTSDLDGGSKLDQRRYTICEDRQPETAIPVPLTKRRFSMHPKASANPLHDTLLQTAGKKRGRKEGKESLSRQNSLDSSSSASQGAPKKKALKSAEILSAALLETESSESTSSGSKMSRWDVQTSPELEAANPFGDIAKFIEDGVNLLKRDKVDEDQRKEGQDEVKREADPEEDEFAQRVANMETPATTPTPSPTQSNPEDSASTTTVLKELETGGGVRRSHRIKQKPQGPRASQGRGVASVALAPISMDEQLAELANIEAINEQFLRSEGLNTFQLLKENFYRCARQVSQENAEMQCDCFLTGDEEAQGHLSCGAGCINRMLMIECGPLCSNGARCTNKRFQQHQCWPCRVFRTEKKGCGITAELLIPPGEFIMEYVGEVIDSEEFERRQHLYSKDRNRHYYFMALRGEAVIDATSKGNISRYINHSCDPNAETQKWTVNGELRIGFFSVKPIQPGEEITFDYQYLRYGRDAQRCYCEAANCRGWIGGEPDSDEGEQLDEESDSDAEMDEEELEAEPEEGQPRKSAKAKAKSKLKAKLPLATGRKRKEQTKPKDREYKAGRWLKPSATGSSSSAEKPPKKPKVNKFQAMLEDPDVVEELSLLRRGGLKNQQDTLRFSRCLVRAKLLKTRLALLRVLTHGELPCRRLFLDYHGLRLLHAWISENGNDDQLREALLDTLESLPIPNRTMLSDSRVYQSVQLWSNSLEQQLAVVPQEKQAALHKRMVALLQKWQALPEIFRIPKRERIEQMKEHEREADRQQKHVHASTALEDQRERESSNDRFRQDRFRRDTTSSRIGKPIRMSGNNTICTITTQQKGSNGAPDGMTRNDNRRRSDIGPPSEQRRTLSKELRRSLFERKVALDEAERRVCTEDRLEHELRCEFFGADINTDPKQLPFYQKTDTNEWFNSDDVPVPAPPRTELLTKALLSPDIDVGQGATDVEYKLPPGVDPLPPAWNWQVTSDGDIYYYNLRERISQWEPPSPEQRLQTLLEENTTQQPLHELQIDPAVLENELIQVDTDYVGSLSAKSLAQYIEAKVRERRDLRRSKLVSIRLISPRRDEDRLYNQLESRKYKENKEKIRRRKELYRRRKIEVLPDAVDEIPVPGKALPIQPYLFSSDEEETKVAAIEQPAAEEEQDSLNMAPSTSHAAMAALGKAVAQPTGLGTVGKRKLPMPPSVTVKKHRQEQRSKKVKSSQSPLTATSAREAHEKFRFEISGHVANFLRPYRKESCTLGRITSDEDYKFLVNRLSYHITTKEMRYCEVSGNPLSCTESVKHKSYDFINQYMRQKGPVYKKPAEND
Protein: AP complex subunit sigma (Q6NSP1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004180}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit {ECO:0000256|ARBA:ARBA00004600}.
Interaction partners:
- AP-1 complex subunit mu-1
- Adaptor-related protein complex 1 subunit mu 2
- AP-1 complex subunit gamma.
- AP complex subunit beta
- Alpha and gamma adaptin-binding protein.
- AP-1 complex subunit gamma
- Solute carrier organic anion transporter family member.
- AP-3 complex subunit mu-1 isoform X1
- Solute carrier organic anion transporter family member
- AP complex subunit beta
Sequence:
MMRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
Protein: Armadillo repeat containing 10 (C9J5N7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004572}.
Interaction partners:
Sequence:
MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAGALEEGTSEGQLCGRSARPQTGGTWESQWSKTSQPEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQIPMKLVTGITFAIIRELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTE
Protein: DNA-directed RNA polymerase II subunit rpb7 (RNA polymerase II subunit B7) (O14459)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase II subunit rpb1
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerase II subunit rpb4
Sequence:
MPFFLKELSLTISLHPSYFGPRMQDYLKAKLLADVEGTCSGQYGYIICVLDSNTIDIDKGRVVPGQGFAEFEVKYRAVLWRPFRGEVVDAIVTTVNKMGFFANIGPLNVFVSSHLVPPDMKFDPTANPPNYSGEDQVIEKGSNVRLKIVGTRTDATEIFAIATMKEDYLGVL
Protein: Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking protein homolog B) (Q55CR0)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004156}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000256|ARBA:ARBA00024187}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004394}. Golgi apparatus, cis-Golgi network {ECO:0000256|ARBA:ARBA00004222}.
Interaction partners:
- t-SNARE family protein
- V-SNARE family protein
- Golgi SNAP receptor complex member 1
- SNARE-complex protein Syntaxin-18 N-terminal domain-containing protein
- t-SNARE coiled-coil homology domain-containing protein
- Alpha-soluble NSF attachment protein
- Protein transport protein SEC23
- Sec1 family domain-containing protein 1 homolog
- t-SNARE coiled-coil homology domain-containing protein
- Vesicle transport through interaction with t-SNAREs homolog 1A
Sequence:
MVLFAMLCRVTDGLMLSESMDTLNPTFDKYRLQAKAIISKLSRVSDKAVTVDANDKYYFAYIIEHEICYLAFCEKSYSKKLVFRFLDDLQKEFYNTYGFEVPSAKRPYQFIAFESFITKTKKLYQDTRAQKNLSNISVELDEVRNIMTKNIKDIVGRGEKLNELNDKTEFLLADSLKYEKQTVALSSKLFFKKYGPILIIAFFALFLYIYLYYF
Protein: enoyl-CoA hydratase (EC 4.2.1.17) (Q9V397)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- acetyl-CoA C-acyltransferase
- HL08109p)
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
- Acyl-coenzyme A oxidase
- Acetyl-CoA acetyltransferase 2
- Acyl-coenzyme A oxidase
- Acyl-coenzyme A oxidase
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Acyl-coenzyme A oxidase
Sequence:
MSATRFLSAVGQISRQQLLQNKCTRALPISAQLLQRRRLMSTNPAPVANKHLHTKVVNGVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADIGMLEACQTAEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEVMLGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYLEKTAVQVANDLASGKLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGLYPAPLKILDVIRAGVDKGTDAGYEAERKGFGELSATPESKGLIALFRGQTECKKNRFGKPERPVKTVGVLGAGLMGAGIVQVSVDKGYQVVMKDATEAGLARGIGQVQKGLETAVKRKRISALERDQTLASLRPTLDYSDFKNADIIIEAVFEDIKVKHRVIKELEAVVPEHCVIATNTSAIPITKIAAGSSRPEKVVGMHYFSPVDKMQLLEIITHPGTSKDTIAQAVAVGLKQGKVVITVGDGPGFYTTRILSTMLSEAIRLLQEGVDPKDLDQYTKKFGFPVGAATLADEVGIDVGSHIAVDLAKAFGERFSGGNLEVMNDLVLAGFLGRKSGKGIFLYDGQKRGTRPVNNDALEIVKQKYALVSKGANAPEDLTLRMVSRFINEAVLCLEEKILDSPLEGDVGAVFGLGFPPFSGGPFRWVDQYGAGKLVSKMQSYAELYGAPFKPAQTLLDMAKDPSKKFYPKTGSSKL
Protein: Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (Q63617)
Organism: Rattus norvegicus (Rat)
Function: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding (By similarity).
Subcellular location: Endoplasmic reticulum lumen.
Interaction partners:
- Endoplasmic reticulum chaperone BiP
- Endoplasmin
- Protein disulfide-isomerase A4
- Nucleotide exchange factor SIL1
- DnaJ homolog subfamily B member 11
- Ankyrin repeat domain 45
- Protein disulfide-isomerase A6
- Stromal cell-derived factor 2-like 1
- DnaJ homolog subfamily C member 10
- Protein disulfide-isomerase
Sequence:
MAATVRRQRPRRLLCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKENERFLGDSAAGMAIKNPKATLRYFQHLLGKQADNPHVALYRSRFPEHELNVDPQRQTVRFQISPQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPAFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINSTAQNIMFYDMGSGSTVCTIVTYQTVKTKEAGTQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRKGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFDRVPGPVQQALQSAEMSLDQIEQVILVGGPTRVPKVQEVLLKPVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSPEEESTLTKLGNTISSLFGGGTSSDAKENGTDAVQEEEESPAEGSKDEPAEQGELKEEAEAPMEDTSQPPPSEPKGDAAREGETPDEKESGDKSEAQKPNEKGQAGPEGVPPAPEEEKKQKPARKQKMVEEIGVELAVLDLPDLPEDELAHSVQKLEDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSATSTWLEDEGFGATTVMLKDKLAELRKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGARLIPEMDQIFTDVEMTTLEKVINDTWTWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRTEPPLNASAGDQEEKVIPPTGQTEEAKAILEPDKEGLGTEAADSEPLELGGPGAESEQAEQTAGQKRPLKNDEL
Protein: Uncharacterized membrane protein YNL320W (P42840)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:16823961}; Multi-pass membrane protein {ECO:0000269|PubMed:16823961}.
Interaction partners:
Sequence:
MLWKVSKMFLGGLVALTTISVATLYHYQNRLVYPSWAQGARNHVDTPDSRGIPYEKLTLITQDHIKLEAWDIKNENSTSTVLILCPNAGNIGYFILIIDIFYRQFGMSVFIYSYRGYGNSEGSPSEKGLKLDADCVISHLSTDSFHSKRKLVLYGRSLGGANALYIASKFRDLCDGVILENTFLSIRKVIPYIFPLLKRFTLLCHEIWNSEGLMGSCSSETPFLFLSGLKDEIVPPFHMRKLYETCPSSNKKIFEFPLGSHNDTIIQDGYWDIIRDFLIEKGFI
Protein: Dentin sialophosphoprotein-like protein (F4IXI9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Glutamate synthase 1, chloroplastic
- Ferredoxin-dependent glutamate synthase 2, chloroplastic
- Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- Delta-1-pyrroline-5-carboxylate synthase B
- Delta-1-pyrroline-5-carboxylate synthase A
- Diaminopimelate epimerase, chloroplastic
Sequence:
MFKGSSKRGGRGGSGGGGSGPSRNRNSFPPPTNRHPSPIGRMSSGGGGGGSAAPRQRSNSTSVKAAASTTVSSRTVEETFNLVPRESSSAFGMIIRLSPDLVDEIKRVEAQGGAAKIKFDAFPNNSTENIINVGGKEFKFTWSGEKGELCDIYEEHQSGEDGNGLLIEAGCAWRKLNVLRTLDESTTSHMKMRSVEAEQRTKSRKAIVLDPGNPSVTKQLAHAEGSPWRMSNKQKKEPPPKKRKVDPPPVPVGGPKPSFRPGASTPTMKNRLSASPGPSPSNQYNTPPYGIGNMAKTHAANENVTPVQTKGRVNMIEKEPSAWKNNVLRDTSGREAINVNKEIDLQSLLVDILKEAPMSLKALEKAVGDKVPNPAKKIEPILKRIANFQAPRYFLKPEAELESYKKHSPDSGSSPEHQQLLPVTECSRDQLPVPGRNNTEKFSLCEQNGEGSLDCLPVHLVEQLSTQENVDIEHHSPGIFHEEKRSENREAQARSSSDSDSDSDNSDSGSDSKSAAGSDSGSSSDSEASSNSKDGSDEDVDIMSDGDREPLLTTQSLEQDAIDLPGHGSSAVEIEGHNSDAVDIDGHDSDAVDIDGHGSDTVDVEGNSSDEGHGSDADRKKNSDNNWKMETTTGTSPTANGEVGISGQEHFTSGHDNLRERQNFIGQLFDDTENTTKNNFKNDKRDISERLGKDQNQKALDFEHYSQKSAHEKNRKSQSCNQLSAVSKDSQHSELKYDAELRNASASQTIDPLRGLLKSSIEKSNRHGKSNKHSDALGNVRKSDKGDHFPLEMLSSRSGKAFRDNQRDDVHLKNKFPRNKKDGESAIRPSLPTETSDRKPDELDGSDKDPKNVSGLSIGSSPLDSQRTYLAKLPKGNGPVLQKQVSELELGELPEPLGEDTALKPIEEKTSFRQSNLKPSTSEKLGIDSDKRRSKKSDSKKAAPPHTVNGSNEHVVEDSERSQKWALQSHGQNLTGTDTEISSQNKNLEDAAYKSRQKDSRARVGNSVEGYGETNKKTPVVKHGSKRASTSRSSRESKRHSSVSNSINGHKDATSIPGGSVVREKQMTSFGEEDSSYLKYEKASPELKGPISDHLQYKAYMQEYNDKYDSYHSINKILESHRNDFQKLGQDLGFAKGRDVERYNKIVEQIKESYCKYGERHKRLKKVFVVLHEELKHLKQRMRDYASSHGKD
Protein: S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) (Methionine adenosyltransferase II) (MAT-II) (P18298)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
Interaction partners:
- Methionine adenosyltransferase 2 subunit beta
- Methionine synthase
- Betaine--homocysteine S-methyltransferase 1
- S-adenosylmethionine synthase isoform type-1
- S-methylmethionine--homocysteine S-methyltransferase BHMT2
- S-adenosylmethionine decarboxylase proenzyme
- Tyrosine aminotransferase
- Methylenetetrahydrofolate reductase
- DNA
- DNA
Sequence:
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQINDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVIPIRVHTIVISVQHDEEVCLDEMRDALKEKLIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKNNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
Protein: Protein CURVATURE THYLAKOID 1A, chloroplastic (O04616)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Determines thylakoid architecture by inducing membrane curvature.
Subcellular location: Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:16461379}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Located almost exclusively at grana margins. {ECO:0000269|PubMed:23839788}.
Interaction partners:
- DnaJ
- PsbP-like protein 1, chloroplastic
- PGR5-like protein 1B, chloroplastic
- PGR5-like protein 1A, chloroplastic
- Protein THYLAKOID FORMATION 1
- Chloroplast stem-loop binding protein of 41 kDa a, chloroplastic
- Protein LHCP TRANSLOCATION DEFECT
Sequence:
MAISVAASSSMAVMVPRVPAVSTRCSAVPYLPPRSFGRSSFTVPLKLVSGNGLQKVELLKTRASSEETSSIDTNELITDLKEKWDGLENKSTVLIYGGGAIVAVWLSSIVVGAINSVPLLPKVMELVGLGYTGWFVYRYLLFKSSRKELAEDIESLKKKIAGSE