wanglab/gogpt-training-data huggingface dataset:
Protein: Guanine nucleotide-binding protein-like 3-like protein (Q9NVN8)
Organism: Homo sapiens (Human)
Function: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:17034816}.
Interaction partners:
- Nucleolar GTP-binding protein 2
- GTP-binding protein 4
- Pescadillo homolog
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- mRNA turnover protein 4 homolog
- Ribosomal L1 domain-containing protein 1
- Ribosome biogenesis protein BOP1
- Nucleolar complex protein 2 homolog
- Protein SDA1 homolog
- Ribosome production factor 2 homolog
Sequence:
MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQALASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD
Protein: DSN1 component of MIS12 kinetochore complex (Q5JW53)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTSVTRSEIIDEKGPVMSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILS
Protein: Ribulose-phosphate 3-epimerase (EC 5.1.3.1) (A0A8I6GEB4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFGSLLSTFYLLSSVCPDAMPPSYPTHFFFLDLDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQKRSLDR
Protein: Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, chloroplastic (EC 1.1.1.8) (Protein SUPPRESSOR OF FATTY ACID DESATURASE DEFICIENCY 1) (Q949Q0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required to supply glycerol-3-phosphate in the chloroplast for the synthesis of glycerolipids. Required for activation of systemic acquired resistance (SAR). Provision of glycerol-3-phosphate may be involved in generating lipid signals necessary for mediating defense responses and SAR.
Subcellular location: Plastid, chloroplast {ECO:0000250}.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial
- Glycerol kinase
- Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
- Dihydroxyacetone kinase
- Glycerol-3-phosphate acyltransferase, chloroplastic
- Lipid phosphate phosphatase 2
- 1-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic
- Putative lipid phosphate phosphatase 3, chloroplastic
- Lipid phosphate phosphatase 1
- Probable lipid phosphate phosphatase 4
Sequence:
MAASVQPACLDLHFSGKHPPLLKHNAIIVRCVSSPNVIPEADSISGPPDIINTNRDQRKVVRIAWEKLVRWSRSLRAKAKTDVLERTRKVVVLGGGSFGTAMAAHVARRKEGLEVNMLVRDSFVCQSINENHHNCKYFPEHKLPENVIATTDAKAALLDADYCLHAVPVQFSSSFLEGIADYVDPGLPFISLSKGLELNTLRMMSQIIPIALKNPRQPFVALSGPSFALELMNNLPTAMVVASKDKKLANAVQQLLASSYLRINTSSDVTGVEIAGALKNVLAIAAGIVDGMNLGNNSMAALVSQGCSEIRWLATKMGAKPTTITGLSGTGDIMLTCFVNLSRNRTVGVRLGSGETLDDILTSMNQVAEGVATAGAVIALAQKYNVKLPVLTAVAKIIDNELTPTKAVLELMNLPQIEEV
Protein: Kelch domain-containing protein 8A (Substitute for delta-EGFR expression 1) (S-delta-E1) (Q8IYD2)
Organism: Homo sapiens (Human)
Interaction partners:
- Peroxisomal targeting signal 2 receptor
Sequence:
MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGGVGTNQLPLKVVEMYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGSLSGRVIVAGGLGNQPTVLETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQGLSDAVEALCVSDS
Protein: Musashi (Q7JN15)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MHALQEGATVLHHQQPPPPTSGEDHLLTADSFFYARSNPMENAAAAAAAAAAGLIDPHHNRDLHQALVASIANNSVAAIGGGLTTAAVLKSAAQQSQQAVQQNQNAVVVTPGLEQPKQEPAQQAALALLKENVNASAGAGQNNGQAAMGGSNKSGSSGRSTPSLSGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQ
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Q9UAV3)
Organism: Caenorhabditis elegans
Interaction partners:
- Ubiquitin-ribosomal protein eL40 fusion protein
- Polyubiquitin-A
- Ubiquitin-like domain-containing protein
- Ubiquitin carboxyl-terminal hydrolase 46
Sequence:
MAAPWTPLESNPSVINPMIEKMGVSGVKTVDVLFFDDESIGKPQHAVILCFPEYKKVDEIMKPIYEQAKAADDSVFFMKQKISNACGTFALFHSLANLEDRINLGDGSFAKWLAEAKKVGIEERSDFLANNAELAGIHAAAATDGQTAPSGDVEHHFICFVGKNGILYEIDSRRPFAREIGPTSDATLVKDAGAACQHLIEKLDNVSFSAIAVVNQ
Protein: HMG box domain-containing protein (A1Z7I6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGRAVKNNRVRSAHCNSAAKATSISGHSMLKQNNDCNGRNPFFQFLAYFRKCSNNCLGHLPSDRVTLIAGKVWNYMSLSEKEPFIAAARRFNYTYRSRSRKVNWVLAQLRKSAAGEECRPQAQWMLMNFLKSWQESVVRNLLDLDHNQN
Protein: Chaperonin-containing T-complex member BBS12 (Bardet-Biedl syndrome 12 protein) (Q6ZW61)
Organism: Homo sapiens (Human)
Function: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:19190184}. Note=Located within the basal body of the primary cilium of differentiating preadipocytes. {ECO:0000269|PubMed:19190184}.
Interaction partners:
- BBSome complex assembly protein BBS10
- BBSome complex member BBS7
- Protein PTHB1
- Molecular chaperone MKKS
- BBSome complex member BBS2
- BBSome complex member BBS4
- BBSome complex member BBS1
- BBSome complex member BBS5
- T-complex protein 1 subunit alpha
- Tetratricopeptide repeat protein 8
Sequence:
MVMACRVVNKRRHMGLQQLSSFAETGRTFLGPLKSSKFIIDEECHESVLISSTVRLLESLDLTSAVGQLLNEAVQAQNNTYRTGISTLLFLVGAWSSAVEECLHLGVPISIIVSVMSEGLNFCSEEVVSLHVPVHNIFDCMDSTKTFSQLETFSVSLCPFLQVPSDTDLIEELHGLKDVASQTLTISNLSGRPLKSYELFKPQTKVEADNNTSRTLKNSLLADTCCRQSILIHSRHFNRTDNTEGVSKPDGFQEHVTATHKTYRCNDLVELAVGLSHGDHSSMKLVEEAVQLQYQNACVQQGNCTKPFMFDISRIFTCCLPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIEGDLTENYRHLGFNKSANIKTVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSERLIEKCINSKRLVIGSVNGSVMQAFAEAAGAVQVAYITQVNEDCVGDGVCVTFWRSSPLDVVDRNNRIAILLKTEGINLVTAVLTNPVTAQMQIKEDRFWTCAYRLYYALKEEKVFLGGGAVEFLCLSCLHILAEQSLKKENHACSGWLHNTSSWLASSLAIYRPTVLKFLANGWQKYLSTLLYNTANYSSEFEASTYIQHHLQNATDSGSPSSYILNEYSKLNSRIFNSDISNKLEQIPRVYDVVTPKIEAWRRALDLVLLVLQTDSEIITGHGHTQINSQELTGFLFL
Protein: Fibroblast growth factor 10 (Q60GK9)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MCKWILTNGASAFSHLPCCCLLLLFLVSSVPVTCHDLGQDMLSPEATNSSSSSSSSFPSSFSSPSSAGRHVRSYNHLQGDVRKRKLYSYNKYFLKIEKNGKVSGTKKENCPF
Protein: Short-form leptin receptor 2 (S4VG78)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MKTMILSAMLTFLVHILIISHSAVLVEPVEVSPHGDLLDLPWQTELCCSSTPAQLHHGGEEEDTGSAPSDTGHPHTLQCLFRNFTSTLGPHPESELSRATCWDILCRVDETWDNVICDLKHPATSSDTSIPGSVALSLQHLTTLPDIEVNSTHGTDCVGEDSITCSVALHVVSSIVVVTANVSNTTAGPLVMLSVPPRTSQRLWKPSPPLNLTHTQTTEGELILSWSDPQPHASPVQLSYEVRYNTSQSTSHPNWLHVNVSGAQWVSLTGLGPGLQYTLQIRSHHPALPHLWSDWSQQHRIRLENVTYLPERVVASFGDSVTVYCVCNDLRVNASTMVWILNSRDRLPKSQYAAVNDRVSKITVRPSEQRLSGTLHCCQPFGEMYSCNYHYSTIYIKDPVIDISCVTSGDLDSMTCRWNNLPIGGINFMSRVADLSCDVMEEAERVGVPVGVVRQAKCESSGYRGVKSCNLQPIRVTSCYKLWMEAKTDNSTRSHPVYITPMDHVKPHPPSGLEAVSMPSGVLKLAWVPPELPIYDMQYQVRYALSTGKAHPFWQVLALQTESWAEVLEPDVCGVYNVQVRCMHINGSGTWSDWSHLLYTTTHNSRAPDQGPDFWRVFQEDPASMQTNVTLLFEHSPIVEPTYCVEELVVQHQDSGGTVTEERIGLVSSYSFEWRGEVHSVTVKAQNSQGSSTRNTHMTLDRHPKRQCVRSFSAAHFQELLCWDEFTLKNRKKENKGLFFEKVYFLSDGCFELDGLYSIST
Protein: Nucleosome assembly protein 1, like 1 (B5DGT5)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MADMDNKDQAELDPADLEDVEDVEEEETGEDVNSKARQLTVQMMQNPQILAALQERLDGLVGSPSGYMESLPKVVKRRVNALKNLQVKCAHIEAKFYEEVHELERKYAALYQPLFDKRSDIVKAAYEPTEEECEWKADEEEELTEEMKEKAKVEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMLQEHDEPILKHLQDIKVKFSDPGQPMSFSLEFYFEPNEFFTNTLLTKTYKMRSEPDENDPFSFDGPEIMGCTGCTIDWTKGKNITLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFTPPDVPESGDLDEDSEAVLAADFEIGHFIRERIVPRAVLYFTGEAIEDDDDDYDEEGEEADDEEGEEEGEEENDPDYDPKV
Protein: Beta-D-xylosidase 1 (AtBXL1) (EC 3.2.1.-) (Alpha-L-arabinofuranosidase) (EC 3.2.1.55) (Q9FGY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in pectic arabinan modification in mucilage secretory cells. Acts also as a beta-D-xylosidase during the remodeling of xylans in vascular development.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000305}.
Interaction partners:
- Alpha-L-arabinofuranosidase 1
- Alpha-L-arabinofuranosidase 2
- Beta-galactosidase 6
- Xyloglucan endotransglucosylase/hydrolase protein 4
- Glutathione S-transferase U10
- Xyloglucan endotransglucosylase/hydrolase protein 24
Sequence:
MSCYNKALLIGNKVVVILVFLLCLVHSSESLRPLFACDPANGLTRTLRFCRANVPIHVRVQDLLGRLTLQEKIRNLVNNAAAVPRLGIGGYEWWSEALHGISDVGPGAKFGGAFPGATSFPQVITTAASFNQSLWEEIGRVVSDEARAMYNGGVAGLTYWSPNVNILRDPRWGRGQETPGEDPIVAAKYAASYVRGLQGTAAGNRLKVAACCKHYTAYDLDNWNGVDRFHFNAKVTQQDLEDTYNVPFKSCVYEGKVASVMCSYNQVNGKPTCADENLLKNTIRGQWRLNGYIVSDCDSVDVFFNQQHYTSTPEEAAARSIKAGLDLDCGPFLAIFTEGAVKKGLLTENDINLALANTLTVQMRLGMFDGNLGPYANLGPRDVCTPAHKHLALEAAHQGIVLLKNSARSLPLSPRRHRTVAVIGPNSDVTETMIGNYAGKACAYTSPLQGISRYARTLHQAGCAGVACKGNQGFGAAEAAAREADATVLVMGLDQSIEAETRDRTGLLLPGYQQDLVTRVAQASRGPVILVLMSGGPIDVTFAKNDPRVAAIIWAGYPGQAGGAAIANIIFGAANPGGKLPMTWYPQDYVAKVPMTVMAMRASGNYPGRTYRFYKGPVVFPFGFGLSYTTFTHSLAKSPLAQLSVSLSNLNSANTILNSSSHSIKVSHTNCNSFPKMPLHVEVSNTGEFDGTHTVFVFAEPPINGIKGLGVNKQLIAFEKVHVMAGAKQTVQVDVDACKHLGVVDEYGKRRIPMGEHKLHIGDLKHTILVQPQL
Protein: Uncharacterized protein FAM241A (Q8N8J7)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Reticulon-4
Sequence:
MCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQDVEDSQNHTGEPVGDDYKKMGTLFGELNKNLINMGFTRMYFGERIVEPVIVIFFWVMLWFLGLQALGLVAVLCLVIIYVQQ
Protein: Protein TESPA1 (Thymocyte-expressed positive selection-associated protein 1) (Q3U132)
Organism: Mus musculus (Mouse)
Function: May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment (By similarity). Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:A2RU30}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:23650607}. Note=May localize to mitochondria-associated endoplasmic reticulum membrane (MAM). {ECO:0000250|UniProtKB:A2RU30}.
Interaction partners:
- Protein THEMIS
- Linker for activation of T-cells family member 1
- Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1
- Stress-70 protein, mitochondrial
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Lymphocyte cytosolic protein 2
- Growth factor receptor-bound protein 2
- Brain acid soluble protein 1
- COP9 signalosome complex subunit 3
- NCK-interacting protein with SH3 domain
Sequence:
MEASVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDALDPEPSSLDDVFQEGNPINKIEDWLQGCGCRDTEEGLSEESGQSNYSGYSSHGTSFEDDLSLGAEATLLSTNGNLFSRNFLQTPRLCQLLDLGSSLASSSMTGGTNKTSSSISEILDQVQEDAEDILFSLGFGHENHKDTSRIPARFFSNPSQAKGINFQLFLKSQVQRMEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVSKTPVQKFTPSNMFWNFDPTDVPSIRILAPEPEPYSPRERLRRAISKMCLYTGSRDRLSSSYNNPKKNSLDQIVWEVMDRVKGEKIQQDPEHRQALGEESVPPIQNTNPSTSSLPCVSYPKEETQGDMCHAHALARPGPQYHINSTQVRRQLWVLQDINEKPRSAENESPWERKSKARKNLFQRVPVDKNIKSLNLPTIQQKQNQGQARHELTNL
Protein: Glucosamine-6-phosphate deaminase 2 (GlcN6P deaminase 2) (EC 3.5.99.6) (Glucosamine-6-phosphate isomerase 2) (Glucosamine-6-phosphate isomerase SB52) (Q8TDQ7)
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway. Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P. At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- N-acetylglucosamine-6-phosphate deacetylase
- N-acetylglucosamine-6-phosphate deacetylase
- Glucosamine-6-phosphate deaminase 1
- Glutamine--fructose-6-phosphate aminotransferase 2
- Glutamine--fructose-6-phosphate aminotransferase 1
- Glucosamine 6-phosphate N-acetyltransferase
- Glucose-6-phosphate isomerase
- Transmembrane protein 18
- BTB/POZ domain-containing protein KCTD15
- Hexokinase-1
Sequence:
MRLVILDNYDLASEWAAKYICNRIIQFKPGQDRYFTLGLPTGSTPLGCYKKLIEYHKNGHLSFKYVKTFNMDEYVGLPRNHPESYHSYMWNNFFKHIDIDPNNAHILDGNAADLQAECDAFENKIKEAGGIDLFVGGIGPDGHIAFNEPGSSLVSRTRLKTLAMDTILANAKYFDGDLSKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTIFVCDEDATLELRVKTVKYFKGLMHVHNKLVDPLFSMKDGN
Protein: Beta-mannosyltransferase 2 (EC 2.4.1.-) (Repressed during hyphae development protein 1) (WRY family protein 7) (Q59MA6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Beta-mannosyltransferase involved in cell wall biosynthesis. Required for the addition of beta-mannose to the acid-labile fraction of cell wall phosphopeptidomannan.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLAWLRHRIRSYNTSTYSSILPSASFGKVYKIGTKLNFTLLALCLLLACSVFFNYFYLADNNGLDIDTKGEEEENVFKDRKMVIFPNNFEITDKNLLEYYLKTLEEPLHPQDTIYRNRFIYKVPDVSYTSQTINLFSGLSQNSQSSKCEDLSSSYSFDVSGPQNKNCDLYKVLGKFLNDDSEYFQEISPLFPKLKEMLVKKEIEKHWFQLIGSSVWLEQYGVHLMTSRIFYSSTGDKVKPVVSLTYVQVFDHEWREIENVELIVPDGEGKYKPMTYPTFLPMSVYHNEKQQQGRFYGVEDPRITLVRNKLGYDEPIIVYNSHHRKITDAKSDNDGESNIHFKAYRSIFMAWLWQNQKGKNNVEEIETGKMKNRVYVKSKELIKPNNKREDKEKNWAPFINYQQRLQQGFDSHVYFMYQFQDLKILKCSLLDEEDCVWEYQFNDKNGAGRLRGGTELVNINQLLTTFDHPEIKRVKDLMPQNREIWIGVARAALEKCGCGDKMYRPNIVILIKDGDDQYRLSHVSPFVGLGIPILPWWPDKGLCDGKNLIIPNGISSWHLNKDEDNSVQDYLTLSISRADSTVDLLHIKGLLKSILFDDPNSKLLELNDYGFNNKNIECAVKSSDAFCKKYGSEYKLNNNKEEDKANGNGKGSSS
Protein: V-set and transmembrane domain-containing protein 4 [Cleaved into: Peptide Lv] (Q8IW00)
Organism: Homo sapiens (Human)
Function: Peptide Lv enhances L-type voltage-gated calcium channel (L-VGCC) currents in retinal photoreceptors.
Subcellular location: [Peptide Lv]: Secreted {ECO:0000250|UniProtKB:T1NXB5}.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MRLLALAAAALLARAPAPEVCAALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGSSATEMRVISLKASEESSFEKTKETWAFFEDLYVYAVLVCCVGILSILLFMLVIVWQSVFNKRKSRVRHYLVKCPQNSSGETVTSVTSLAPLQPKKGKRQKEKPDIPPAVPAKAPIAPTFHKPKLLKPQRKVTLPKIAEENLTYAELELIKPHRAAKGAPTSTVYAQILFEENKL
Protein: Anterior gradient protein 2 homolog (Zagr2) (Q5RZ65)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000255, ECO:0000305}. Endoplasmic reticulum {ECO:0000250|UniProtKB:O88312}.
Interaction partners:
- Mucin 2.2, oligomeric mucus/gel-forming.
- SAM pointed domain-containing Ets transcription factor
Sequence:
MLKGLLSVLLVMVALSSALGKPEKTTPKKEKEKRVPQTLSRGWGDQLIWAQTYEEALFWSRSKNKPLMVIFHLEDCPHSQALKKAFAEDKEIQKLADEDFVILNLVYETTDKHLSPDGQYVPRIIFVDPSMTVRADITGRYSNRMYAYEPADMKLLLSNMQRALKFLKTEL
Protein: Protein amnionless (D3ZFK9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
- Cubilin
- Low-density lipoprotein receptor-related protein 2
- Cobalamin binding intrinsic factor
Sequence:
MGALGRVLLWLQLCALTRAAYKLWVPNTSFDTASNWNQNRTPCAGDAVQFPADKMVSVLVRDSHAISDMLLPLNGEFVLASGAAFSAAGGDSDPACNPGAPLLFRNPDRFSWLDPHLWSSGTQESGIFFVDAERVPCTYDDVLFPRNGSFRVALGPGPNPVHVRSVSAVGQTFTRDEDLAAFLASREGRLRFHGSGALRVGSQACTDATGCVCGNAETLPWICASLLQPLGGRCPEATCQDPVRPQGQCCDLCGAIVSLTHDPTFDLERYRARLLDLFLKQPQYQGLQVAVSKVLRDAHTEIQVVLLETRPATGAAGQLGHALLQDAVAQGSVLGIVSATLRQSGKPTAANSALDQNGSGAGLAGGVAAVVLLALVGTVLLLLHRSGRLRWRRHGDAEPTSAGLPLGFRNPIFDVMVFKQQQASVEFADSTQKVDILDIDTNFGCFVNPLFAGEAEAEA
Protein: Nicalin (Q9VKZ7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
- PAT complex subunit CCDC47
- BOS complex subunit TMEM147
- Calcium load-activated calcium channel
- LD28380p
- DSec61alpha
- Nodal modulator 3
- Buddy of Hmr 1
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein eL19
- Protein transport protein Sec61 subunit beta
Sequence:
MMNEADSLTEIFRGGLPHCLLIVFSLLLTCSPVMPSEFEVISMSKYDLNGQHYGSRVASISLEARSLYSWNTSRHCVLTRLTDLSIHDFDKLRQGAGGLILMLPANILNLDPETKELITILEQSMLTHTAAVPIYFAPYNKDLEKIIDDITYTTTDSPGQNQTALAQLVVTVSANRYHINVGGGSIAANKNSKIPIIHGELIPNQLALKPTESVADGQKLPVILITANLKTFGIYNDYPVNADAAVLLVLMELFSKLHYTSSMAPKYRLRFLLSDAGVLLNFQGSKKWLEVDDNALQNVEFVLCLDTISESLSYTTENALYMHVSKPPKDKTSISNFFKLLKSSAEKYSNGLAVEGVHKKINLADTKLAWEHERFSIKRYPSFTLSSVKSPRSPIRTTIFKNDESRLVEHTLNTTRIIAEALASFMYKVDPTSSIFEGQLAIKEENILPYFGVKSILHNNDVKDAFEKYLNNVKIIYDKPDARDPEFMFYNENEVKLNVYRVKPAIFDLFLTFVIGAYLLAVFLAIQYFPRFYDEVSKLTKEDPAGQSNGHSSERVRMKSH
Protein: Protein kinase, putative (EC 2.7.1.-) (Q57WV2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MENYQLLNQLGDGTFGCVVKALHKSSGQFVAIKKMKQKYYSWDECMKLPEVVVVRRVHGHPNIVKMREVIREKNELFFVFEFMDGDLLGVIRRAKQMQSYGSGTSGPALAYPKIKSYTFQILQSLAYLHRAGYFHRDMKPENLLVRKDPSTSAQEIVKLADFGLVKEIRARPPYTDYVSTRWYRAPELLLQDRCYSSPVDIWAVGCIIAEMITTRPLFAGSNEVDQLHKIMAVLGSPNESVWPNGMVLAKKIRYNFPSINGVGLERVMPPHVPPHAMDLMKQMLNYDPKRRPTAQQCLQHPYFNVGVDEENFAPTNVPKQMAEALKKHTSGPQSAPSGAVVPNSDTKGDRPPVGATTAVPKAGGPSNSPPVVPQQNSYSPSNESSDRKPDVQPKFGSNVKTTLANMKTSPLPPEAKPGKFSPSNNKEIPSRTVAQPPPASNNDELDLDGLIDDFAGELKTLGLHPQQKQHGSTSLQSNATPGKDITNCGSSGSQRKSGVDFAKPPPMEGGMVATLLNSTRYKLSSFQSSENKTYTNSLGKAHPQGNSPATLASVGPSVGSQAVSPSIKALLAKHREHNQGSNS
Protein: Killer cell immunoglobulin-like receptor 3DS1 (Natural killer-associated transcript 10) (NKAT-10) (Q14943)
Organism: Homo sapiens (Human)
Function: Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
Sequence:
MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHREWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKKKCCCNGPRACREQK
Protein: Vacuolar import and degradation protein 27 (Q1MTR3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in the negative regulation of gluconeogenesis. Required for vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase) (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- tRNA
- Uncharacterized protein C4.03c
- GTPase-activating protein gyp7
- Protein kri1
- Ribosome quality control complex subunit 1
- Nuclear membrane organization protein apq12
Sequence:
MFMLKSLGKYIWGNTNSTEIVQIPYGQLYSVHENYRECMFKDASASIRRTTAEFQYQLVIQRAYEEGEEELEDDGDEAEDEQSFLLDEKLHLRFDVNKDSITIMWDNPDFQDGTLYEFTCENCLQEGVAYTFEMVALQCMYERKYRQSHEKATLADLEQFSNPITRPSKEVDSLENIVTKLDLESEDLMRLKKQEQLDDEIAKKYLLGQQEAEEPLVQQQTSIVNPEKEEVTKTENIKSLEGELMGTISAELHLFDAVEEVFILQDPNVEASVFDLGDWNYWFTISTEEKTWLSQSVDADMNPVFSFEHLSFIWNYFDANSNAFSWLLRFDSQVRMEQFQELLMRALWESLNQQRWLKIDDEQRDYVMETFHEDEELEDSEDEEFARQQLLSRKEEEEEEDEEASDFEDSFADFSDGEADDLDESRWRKEAAKEHNSLLAVGYKNDRSYVVRNNKIGVFKHVDEKGLKFQTALNNLSTPKGKSLRPSKLMLHNQDSSILFQTENAPHSLYHMDIEYGKIVDEWKVHDDVPLVTFTPDNKFAQMTAEQTLIGLSNNSIFRIDPRVEGNKLVAEQFKQYATKNDFSSAATTENGYIAVASNKGDIRLFDRIGVNAKTALPALGEAIIGVDVTASGDFVLATCKTYILLIDTRIKEGRYAGRLGFERNFAKDKKPKPKRLQLSPQHIAMMQRELKGGASFTPAKFNTGIDAKETTIVSSIGPFLISWNLDRVKRGFTDSYKIRRYDANVQAEDFRFGTDRSLIVALPDDVAMVDKSSLRRPTRESICTPVKKLRSKHDIVNAPY
Protein: Type 3 secretion system ATPase (EC 7.4.2.8) (Q3BYK0)
Organism: Xanthomonas euvesicatoria pv. vesicatoria (strain 85-10) (Xanthomonas campestris pv. vesicatoria)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Type 3 secretion system stator protein
- Lipoprotein
- Flagellar biosynthetic protein FlhB
- HrcT protein
- HrcV protein
- HrcR protein
- HrcQ protein
- Flagellar motor switch protein FliN
- Flagellar biosynthesis protein FlhA
- HrpB2 protein
Sequence:
MLAETPLLETTLERELATLAVGRRYGKVVEVVGTMLKVAGVQVSLGEVCELRQRDGTLLQRAEVVGFSRDLALLAPFGELIGLSRETRVIGLGRPLAVPVGPALLGRVLDGLGEPSDGQGAIACDTWVPIQAQAPDPMRRRLIEHPMPTGVRIVDGLMTLGEGQRMGIFAAAGVGKSTLMGMFARGTQCDVNVIVLIGERGREVREFIELILGADGLARSVVVCATSDRSSIERAKAAYVGTAIAEYFRDRGLRVLLMMDSLTRFARAQREIGLAAGEPPTRRGFPPSVFAELPRLLERAGMGESGSITAFYTVLAEDDTGSDPIAEEVRGILDGHLILSREIAAKNQYPAIDVLASLSRVMSQIVPYDHSQAAGRLRRLLAKYNEVETLVQVGEYRQGSDAVADEAIDRIDAIRDFLSQPTDQLSAYENTLELLTSVTDDA