wanglab/gogpt-training-data huggingface dataset:
Protein: Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic (AtBSD2) (Q9SN73)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Chloroplast chaperone required for RuBisCo biogenesis and translational regulation of the RuBisCo large subunit (RbcL). Stabilizes an end-state assembly intermediate of eight RbcL subunits until the small subunits (RBCSs) become available to produce a complete stable RuBisCo complex containing eight small and eight large subunits.
Subcellular location: Plastid, chloroplast stroma {ECO:0000250|UniProtKB:Q9XF14}. Note=Associates with chloroplastic polysomes. {ECO:0000250|UniProtKB:A0A2K3DZC4}.
Interaction partners:
- Rubisco accumulation factor 1.2
- Thylakoid lumenal P17.1 protein
- Co-chaperone protein p23-1
- Co-chaperone protein p23-2
- Chaperone protein dnaJ-like protein
- Protein disulfide-isomerase LQY1, chloroplastic
- DnaJ/Hsp40 cysteine-rich domain superfamily protein
- Ribulose bisphosphate carboxylase large chain
- 20 kDa chaperonin, chloroplastic
- Protein PHOTOSYSTEM I ASSEMBLY 2, chloroplastic
Sequence:
MANSLCFFSSPPTFCFQSPSKNPKPSHFFSTNDNTSSLVQKRELLQTSRSQSFEVKAANNNPQGTKPNSLVCANCEGEGCVACSQCKGGGVNLIDHFNGQFKAGALCWLCRGKKEVLCGDCNGAGFIGGFLSTFDE
Protein: Ubiquitin-conjugating enzyme 28 (F4I5B8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MASKRILKELKDLQKDPPTSCSAVDNASKLLVLIELEDCCRRFSNCSCILLLEKSQDIAMAHVLLCPVAEDMFHWQATIMGPSDSPYSGGVFLVTIHFPPDYPFKPPKVAFRTKVFHPNVNSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLVPEIAHMYKTDRAKYESTARSWTQKYAMG
Protein: E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E) (P98105)
Organism: Rattus norvegicus (Rat)
Function: Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P16581}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P16581}.
Interaction partners:
- Golgi apparatus protein 1
- Selectin P ligand
- CD44 antigen
- L-selectin
- Leukosialin
- Vascular cell adhesion protein 1
- Integrin beta
- Intercellular adhesion molecule 1
- Alpha-
- P-selectin
Sequence:
MNASCFLSALTFVLLIGKSIAWYYNASSELMTYDEASAYCQRDYTHLVAIQNKEEINYLNSTLRYSPSYYWIGIRKVNNVWIWVGTQKPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPKDSGMWNDERCDKKKLALCYTASCTNTSCSGHGECVETINSYTCKCHPGFLGPKCDQVVTCQEQEYPDHGSLNCTHPFGLFSYNSSCSFSCERGYVPSSMETTVRCTSSGEWSAPAPACHVVECKALTQPAHGVRKCSSNPGSYPWNTTCTFDCEEGYRRVGAQNLQCTSSGVWDNEKPSCKAVTCDAIPRPQNGSVSCSNSTAGALAFKSSCNFTCEHSFTLQGPAQVECSAQGQWTPQIPVCKASQCEALSAPQRGHMKCLPSASAPFQSGSSCKFSCDEGFELKGSRRLQCGPRGEWDSEKPTCAGVQCSSLDLPGKMNMSCSGPAVFGTVCEFTCPEGWTLNGSSILTCGATGRWSAMLPTCEAPANPPRPLVVALSVAATSLLTLSSLIYVLKRFFWKKAKKFVPASSCQSLQSFENYQGPSYII
Protein: Formylglycine-generating enzyme (FGE) (EC 1.8.3.7) (I6Y8I5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile.
Interaction partners:
- Possible hydrolase
- Possible arylsulfatase AtsA
- Ribonuclease Z
- Linear primary-alkylsulfatase
- Uncharacterized oxidoreductase Rv0484c
- Conserved protein
- Probable arylsulfatase AtsB
- Probable sulfatase
- Possible arylsulfatase AtsD
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2
Sequence:
MLTELVDLPGGSFRMGSTRFYPEEAPIHTVTVRAFAVERHPVTNAQFAEFVSATGYVTVAEQPLDPGLYPGVDAADLCPGAMVFCPTAGPVDLRDWRQWWDWVPGACWRHPFGRDSDIADRAGHPVVQVAYPDAVAYARWAGRRLPTEAEWEYAARGGTTATYAWGDQEKPGGMLMANTWQGRFPYRNDGALGWVGTSPVGRFPANGFGLLDMIGNVWEWTTTEFYPHHRIDPPSTACCAPVKLATAADPTISQTLKGGSHLCAPEYCHRYRPAARSPQSQDTATTHIGFRCVADPVSG
Protein: Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (A0A8I5ZKV9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
GAPGVPREYKGRFRGRLFGAPRFGGSRTGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVANMHNGMNQQAYAYPATAAAAPMIGYPMPTGYSQ
Protein: Pyruvate kinase (EC 2.7.1.40) (Q9SJQ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- L-lactate dehydrogenase
- Bifunctional enolase 2/transcriptional activator
- Cytosolic enolase 3
- Enolase 1, chloroplastic
- D-lactate dehydrogenase [cytochrome], mitochondrial
- Malate dehydrogenase 2, mitochondrial
- Inosine triphosphate pyrophosphatase
- Malate dehydrogenase 1, mitochondrial
- NADP-dependent glyceraldehyde-3-phosphate dehydrogenase])
- Malate dehydrogenase, chloroplastic
Sequence:
MHSSHLLLEEPIRMTSILEPSKSSFFPALTKIVGTLGPKSRSVEVIAGCLKAGMSVARFDFSWCDADYHQETLENLKIAVKSTKKLCAVMLDTVGPELQVINKTEKAISLKADGLVTLTPSQDQEASSEVLPINFDGLAKAVKKGDTIFVGQYLFTGSETTSVWLEVEEVKGDDVICISRNAATLGGPLFTLHVSQVHIDMPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQARELLNSCGDLSQTQIFAKIENEEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVLTRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICCEAEKVFNQDLFFKKTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLTTNQLKWSFSGAFEARQSLIVRGLFPMLADPRHPAESTSATNESVLKVALDHGKQAGVIKSHDRVVVCQKVGDASVVKIIELED
Protein: Toll-like receptor 2 (F1QWS9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MFACLFSFIMSTAKLQFTHRRGVDTIMAVRMRLVGTMTAIILIMFILAQGLECSQTCKCDQMYFCNCSSNNLHQVPTVPSDVLGLDLSFNQIESINMTDLSSYNELIILNLHKNKLRHIHRDAFKSQHNLEVLDLSLNNLNNLSPSWFHKLKSLQQLNLVGNPYSTVGPAPIFKSLVNLRTLHLGSPSLRELHKNGLDVLTHLDEMTFFGSNLRSYENGSLKAARPIGSVSLSLQNLFESDPELVSKVLQDVSHPETLLIIKDVTMKTNTSTEPFKMVKEGGTKSLTFQNSSTTDQALTSFLEFMDGSPLSFIGLEDIQFVGIGEWQKAKYTHHDSLRTAYLRNIEIEGFFGFSSMIELGFLLKHFHNVSVINATVFVIPKETTFLLKNLEYMDLSQNLLTDLTIQPTLYTGSGAYQNLNMLNVSQNVLKSLGLMSRLVTNLKKLKYLDLSYNSFVSMPEKCSWPVTLRFLNLSSTKLSTLTPCLPSSLTVLDLSENDLKAFKQRFPHLTTLILTGNRLMKLPDGKLFPSLNTLLIQRNALRMFNQSSLRSFKTLLYLEAGANNFVCSCKFVSFFKKDVEDLITLQDGRQNYVCNTPFTLRGNAIDSVRLSVFECYMIPAVSVLCFGIITALGLVVLTCHKLHVIWYLQMTKAWIQAKRKPAVGRLPEELRYDAFVSYSQHDAEWVEEILVAELEDTQPSFSLCLHKRDFRPGRWIVDNIIDSIEKSYRTLFVLSEHFVSSEWCRYELDFSHFRIMDEHNDSAVLVLLEPIKKETIPKRFCKLRKIMNSRTYLEWPEDEDKRDEFWSNLRAALQRDEC
Protein: Uncharacterized protein (Q9VUI7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Transporter
- Sodium-dependent nutrient amino acid transporter 1
- Transporter
- Transporter
Sequence:
MKAIRCKSSSQVSSQVMIRVVLMPLYLVLVAAVKTSVVAQTTPSNAKVNAAFQIFHGDIDKYELCVKLIRVCRKVWDQAPDYSDSEEKTPDENEVNGEDMAEYKRGDCIPTGLSKDGERLFWKIVAKWQKEIDDRFLIQNLFVVIMTTENGRNTKLTFGKWNGWCNRTDNYDEITEVANDSNEFVSDLKKRQNALENCNIDATFGRWIFNEIRSTRQLDKDINIISDFMSKFDKNAKSKCCPYELIRDRLEIINDGIDFLEELQGIESSLVTNYTDVNTDLFHLKERVENFSNLIQSEGGNYSTGKCCPNILSELETFRNDFADNLKFEGTTTLKLDHQPYIQKEKSLREMILSYVGDIDLLETSLMNQTKKSTYCEGEQTQIKNLEQIINDIRPEKFLGELLKQIEPLNENLAEANKTISDAEKLLNLEKENLQKLNSLYGEEWHQKNILKDLESKVSQLEYKINNLSLLEDVNWPKLRKSVDDVNKMFENSPSFFANITVISMKNGMKFKGQSTSDFAINLKKKSEVRFCTNESIKLNDYLEKIEKDKNKIVAYYNQQENVVRAHFNELLDKEKELKYHSPKSLTLKKSDMTYKVDPSVSSTSSLQLDINQLEKDIDNLTENGIEKFERQLQYTRLKFEMDKQQIDRKLEEQLRNINLFREEMKREENLIAERLAKLDTPKEYDEKLSKLEAEAMDFPKQIANSEKTLLDQIASLQQQIKTLEKEAENTEHRADLCDAECDFGDLDSIDELMNRVQAVKNKLNN
Protein: Stromal processing peptidase, chloroplastic (EC 3.4.24.-) (Chloroplast processing enzyme) (Q9FIH8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cleaves presequences (transit peptides) from chloroplastic protein precursors. Initially recognizes a precursor by binding to the C-terminus of its transit peptide and then removes the transit peptide in a single endoproteolytic step. In a next step, pursues the cleavage of transit peptide to a subfragment form (By similarity).
Subcellular location: Plastid, chloroplast stroma {ECO:0000250|UniProtKB:Q40983}.
Interaction partners:
- Alpha/beta-Hydrolases superfamily protein
- At2g41950/T6D20.26
- Probable CCR4-associated factor 1 homolog 2
- Serine carboxypeptidase-like 34
- Serine carboxypeptidase-like 26
- Prolyl carboxypeptidase like protein
- Serine carboxypeptidase-like 42
- Presequence protease 1, chloroplastic/mitochondrial
- Alpha/beta-Hydrolases superfamily protein
- Prolyl endopeptidase
Sequence:
MASSSSSIFTGVKFSPILAPFNSGDSRRSRYLKDSRNKVRFNPSSPRLTPHRVRVEAPSLIPYNGLWAAQPNSHKGRLKRNIVSGKEATGISLSQGRNFCLTCKRNQAGIRRALPSAFVDRTAFSLSRSSLTSSLRKHSQIVNATLGPDEPHAAGTAWPDGIVAERQDLDLLPPEIDSAELEAFLGCELPSHPKLHRGQLKNGLRYLILPNKVPPNRFEAHMEVHVGSIDEEEDEQGIAHMIEHVAFLGSKKREKLLGTGARSNAYTDFHHTVFHIHSPTHTKDSEDDLFPSVLDALNEIAFHPKFLSSRVEKERRAILSELQMMNTIEYRVDCQLLQHLHSENKLGRRFPIGLEEQIKKWDVDKIRKFHERWYFPANATLYIVGDIDNIPRIVHNIEAVFGKNGLDNESTPSSPSPGAFGAMANFLVPKLPAGLGGTFSNEKTNTADQSKMIKRERHAIRPPVEHNWSLPGTSVDLKPPQIFKHELLQNFAINMFCKIPVSKVQTFGDLRNVLMKRIFLSALHFRINTRYKSSNPPFTSVELDHSDSGREGCTVTTLTVTAEPQNWQNAVKVAVQEVRRLKEFGVTRGELTRYMDALLKDSEHLAAMIDNVSSVDNLDFIMESDALSHTVMDQTQGHETLVAVAGTVTLEEVNTVGAKVLEFISDFGRPTAPLPAAIVACVPTKVHVDGVGESDFNISPDEIIESVKSGLLAPIEAEPELEVPKELISQSQLKELTLQRNPCFVPIPGSGLTKLHDKETGITQLRLSNGIAVNYKKSTTESRAGVMRLIVGGGRAAETSDSKGAVVVGVRTLSEGGRVGDFSREQVELFCVNHLINCSLESTEEFIAMEFRFTLRDNGMQAAFQLLHMVLERSVWLEDAFDRARQLYLSYFRSIPKSLERATAHKLMIAMLNGDERFVEPTPKSLQSLNLESVKDAVMSHFVGDNMEVSIVGDFSEEEIERCILDYLGTVKASHDSAKPPGSEPILFRQPTAGLQFQQVFLKDTDERACAYIAGPAPNRWGFTVDGDDLFQSVSKLPVAHDGLLKSEEQLLEGGDRELQKKLRAHPLFFGVTMGLLAEIINSRLFTTVRDSLGLTYDVSFELNLFDRLNLGWYVISVTSTPGKVYKAVDACKSVLRGLHSNQIAPRELDRAKRTLLMRHEAELKSNAYWLNLLAHLQASSVPRKELSCIKELVSLYEAASIEDIYLAYNQLRVDEDSLYSCIGIAGAQAGEEITVLSEEEEPEDVFSGVVPVGRGSSMTTRPTT
Protein: Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2) (V9HW91)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTSFRLALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYGAKYFPEYAEKIPGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKKP
Protein: Nuclear receptor subfamily 1 group I member 3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67) (O35627)
Organism: Mus musculus (Mouse)
Function: Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (By similarity).
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Recruited to the cytoplasm by DNAJC7.
Interaction partners:
- Retinoic acid receptor RXR-alpha
- Nuclear receptor coactivator 2
- Nuclear receptor coactivator 1
- Nuclear receptor subfamily 0 group B member 2
- Cytochrome P450 2B10
- Cytochrome P450 3A11
- Mediator of RNA polymerase II transcription subunit 1
- Cytochrome P450 2B9
- Nuclear receptor corepressor 2
- Nuclear receptor corepressor 1
Sequence:
MTAMLTLETMASEEEYGPRNCVVCGDRATGYHFHALTCEGCKGFFRRTVSKTIGPICPFAGRCEVSKAQRRHCPACRLQKCLNVGMRKDMILSAEALALRRARQAQRRAEKASLQLNQQQKELVQILLGAHTRHVGPMFDQFVQFKPPAYLFMHHRPFQPRGPVLPLLTHFADINTFMVQQIIKFTKDLPLFRSLTMEDQISLLKGAAVEILHISLNTTFCLQTENFFCGPLCYKMEDAVHAGFQYEFLESILHFHKNLKGLHLQEPEYVLMAATALFSPDRPGVTQREEIDQLQEEMALILNNHIMEQQSRLQSRFLYAKLMGLLADLRSINNAYSYELQRLEELSAMTPLLGEICS
Protein: Uncharacterized protein AT4g09430 (Q9M0P9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MASSSTSSPTRVKEYDVFLSFRGADTRNNIVSYLHKALVDVGIRTFKDDKELEEGDIISEKLVNAIQTSWFAVVVLSEKYVTSSWCLEELRHIMELSIQDDIIVVPIFYKVEPSDVRYQKNSFEVKLQHYRDPEKILKWKGALTQVGNMSGKHFQTCSDEATNIAEIVSKISNRLRKMKPTDLINLVGMDAHMEKMQLLLDKEPKSEVRMIGILGMGGIGKTAIANYLYNQFSHEYWAHCFIEDAWNTNDPTHLQRKLLSHICNDENAKLFTREAGAMKIKGILKHKKFFLVIDGVNKAEQVHALAKERSWFGPGSLIIITTRDRGLLNSCGVNNVYEVKCLDSKDALQVFEKFAFGGRNPPFHGSERLFTRASQLAHGLPYALVAFASHLSEQTTIEGWEDELFRLEDYPQKNVEEILRASYDDLDYYEQSVFLQVACLFNGSFLWLIRAFLGKLGSRINSLRAKSLLDISNDGRLIMHFLVEQIGKEIVRQQSNCIPSEQKFLWKPEEIYDVLARNIFLKHVVDITSKLQLISDVSSITHGLKLLHWDAYPLETLPFSFQSSTLVEINLRYSNLKHFWDETKVYRSKQLPNLRRLDVTGSTSLVELPDLSDSMNLEELIMEGCRSLRQTPWSLNRLPLRKLNMVKCDSLMGLLLVTDDHNQPKASRPSPYRHINLLLLDTVTALSSLTELSIQGEISVKLLHTLIGSAEHLSFTCEQQIPDQLKITMAQKTGSIQPLHLIKTLVIERFNYGAREAPFSCQSFSSFPCLTELKLINLSIREIPQDIDCLLSLRKMDLTGNDFVHLPKTMAQLTKLECLTLRNCRQLKALPLLTPTLTLPGLDNQPRGLIELCIDNCKNLQSLQDQLLCYNTSLAYLDLSNHDFERIPTSIRHLSSLNTLCLKNCKKLKYVEELPLSLNHLYAHGCDYLENVTLSPNHTIKHLDLRDCPRLKQSEQIKTLVSNERHGEAFGLRSGSSGFSNYSQNPKTSGREIPKTALPKLGLQLKLPQTHTEIVILCGARLTTNKINMEHHFSCHFIL
Protein: Post-transcriptional regulator MKT1 (Inactive endonuclease MKT1) (Q587E3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Involved in post-transcriptional regulation of gene expression. Promotes mRNA stabilization by recruiting a complex containing PBP1, LSM12 and XAC1 to mRNAs. Recruited to mRNAs by sequence-specific RNA binding proteins. May regulate translation through interactions with the EIF4E6-EIF4G5 translation initiation complex.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:24470144}. Cytoplasm, Stress granule {ECO:0000269|PubMed:24470144}. Note=Localizes to polysomes (PubMed:24470144). Partially localizes to starvation-induced stress granules but not to heat shock-induced stress granules (PubMed:24470144). {ECO:0000269|PubMed:24470144}.
Interaction partners:
- PAB1-binding protein 1
- F-box domain-containing protein
Sequence:
MYPRHDDVSLFQRFVNDHKLEEKGLPLYQLAQLEGTDQVMLGVDGTKIIDMITQAVREREKMAIYTYTTPYTVYEKINEFRTMFQSIKNCTPVFVFNGIQYSPDSAEEFGREKNVVPSEVAALTGTDSSRLSNTTNVRFAEIHKKTANRFVVEEDVEGQIIRIFRSEFKNTIRAPYLAWAQLSSFRHCNHRHISEVYGCLELLAFPGIDRVVTNINPTRGTFDVVYKARVLEAARLSEEDLSSLILVESRSRVMRTVTLKFSSLEDMIKKVVRYKGSTIGASFAQQLHEEAIRASEANRMRASNQRGAAFRNLSAFASPVLTLTPPHCLPLHFLYGIPGFPHADAESFVGLPLPPVLYYIMSAGLLSPSLFAAVSQETVVDDWPLVDSIKYRDVAETVLPLRVQTIYQLAWTMSRGLGSISWFRRYNVLPARVSKLHVPPAIQLDGWALHSVTVPRGLHLVDVMEFAHLACSVDQVIYNTMEETYAAILLQSLDLLGYLTHETQDLHEEGQSSEPSTFGRALQLCSVPTLSEYTVLLIELARTNAISTEPFRITTEEVSPRDTPRDIVFASRVLSIIPLNVSGPWTAPIDAELAAFSMLSRMISRSIRQLLEAITTLMFSKGRTHVPLHRIGEIQRLLPFSTPVEFGCGVLVEYMLMKDKCTLKDLEEAFPECTYLRHDLATLFYFWDLAVQVLQRIETKENFCVDQHCLSSANERMKRAQKNLNILTGVRETYY
Protein: Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (P24483)
Organism: Rattus norvegicus (Rat)
Function: Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:2170421}.
Interaction partners:
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- Cholesterol side-chain cleavage enzyme, mitochondrial
- Iron-sulfur cluster assembly enzyme ISCU
- Cysteine desulfurase
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH-ubiquinone oxidoreductase chain 3
- Fatty acid desaturase 6
- NADH-ubiquinone oxidoreductase chain 4
- NADH-ubiquinone oxidoreductase chain 1
Sequence:
MAAAPGARLLRAACASVAFRGLDCRRLLVCGTRAGPAVPQWTPSPHTLAEAGPGRPLSVSARARSSSEDKVTVHFKNRDGETLTTKGKVGDSLLDVVIENNLDIDGFGACEGTLACSTCHLIFEDHIYEKLDAITDEENDMLDLAFGLTNRSRLGCQVCLTKAMDNMTVRVPEAVADVRQSVDMSKNS
Protein: Mitochondrial ribosomal protein S28 isoform 1 (A0A0S2Z563)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAALCRTRAVAAESHFLRVFLFFRPFRGVGTESGSESGSSNAKEPKTRAGGFASALERHSELLQKVEPLQKGSPKNVESFASMLRHSPLTQMGPAKDKLVIGRIFHIVENDLYIDFGGKFHCVCRRPEVDGEKYQKGTRVRLRLLDLELTSRFLGATTDTTVLEANAVLLGIQESKDSRSKEEHHEK
Protein: Stress-response A/B barrel domain-containing protein At5g22580 (Uncharacterized protein At5g22580) (Q9FK81)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in stress response.
Interaction partners:
- Electron carrier/ protein disulfide oxidoreductase
Sequence:
MATSGFKHLVVVKFKEDTKVDEILKGLENLVSQIDTVKSFEWGEDKESHDMLRQGFTHAFSMTFENKDGYVAFTSHPLHVEFSAAFTAVIDKIVLLDFPVAAVKSSVVATP
Protein: Voltage-dependent L-type calcium channel subunit beta-2 (Calcium channel voltage-dependent subunit beta 2) (A2SZ54)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004278}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004278}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004278}.
Interaction partners:
Sequence:
MKASWIRLLKRATGNRVKNNIGGSADSYTSRPSDSDVSLEEDKETLRREAERQAQAQLDKAKSKPVAFAVRTNVGYSASSEDDVPVPGTGISFDPKDFLHVKEKFNNDWWIGRLVKEGCDIGFIPSPVKLESSRLRQEQRAKQGRFYSSKSGANSSSSLGDIVSNSRKSTPPSSAKQWQKSTEHAPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRITITRVAADISLAKRSVLNNPSKHAIIERSNTRSNLAEVQSEIERIFELARTLQLVVLDADTINHPSQLGKTCLAPIIVYIKITSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPSELFDIILDENQLEDACEHMADYLELYWKSTHPPSGAPSTPLLDKLSAVTAAAVACKEQLTNTQPKGTGSDQHADRAAADRTSFYEDYHHHHHPQQQHYQTQKQESFEEEEEEEDDDEEENTDERHDNRDQQDHHKNQHSSSTRTERHHHHRHHHHHHHHRHHHSRTGRTLSKQETLESTETQTHSQPQQEEEQESVQPNHHRHHHHHHRHHHRNEKEKEHDHNERNSRQRGKQKSQREHHHHERRKHYIEQ
Protein: Probable serine/threonine-protein kinase nek2 (EC 2.7.11.1) (Never in mitosis protein A-related protein kinase 2) (NimA-related protein kinase 2) (Q55BN8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in centrosome biogenesis. Seems to be required for recruitment of centrosomal material and might be involved in de novo centrosome formation.
Interaction partners:
- Probable inactive serine/threonine-protein kinase bub1
- Mitotic spindle assembly checkpoint protein MAD2A
- Anaphase-promoting complex subunit cdc20
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 1
- Anaphase-promoting complex subunit 8
- Anaphase-promoting complex subunit 6
- Anaphase-promoting complex subunit 2
Sequence:
MDQYEILGALGKGSFGVVSKIKRKEDGRVLVWKEICYENMQEKEKQLLVNEVNILQKLKHQNIVRYYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCRNERTYMDEEVIWRTLLQILSALQEIHNRKDGVILHRDIKPGNLFLDENKNIKLGDFGLAKILNESLYAHTFVGTPYYMSPEQIHGLKYNERSDVWSVGCLIYEMATLSPPFEATNQAQLTSKIQVGRYNPIPSQYSEHLSKVISLMINVDPKSRPNVNELLGYSFISFKVKERKLNIYYQGLKQMDEDLKIKEKKLSDIERDLQVKEQHLLLREQQINQREKLLLDKENFETQSRINIMNQQLQQQQQNQLQHQISNLSLNCNNSVNSCSSSSNNNTTNSINTQQQIHIQHNTQQQQQQQQTFQPYQIKRTFTTPLPNFK
Protein: Gelsolin-like protein 1 (Q21253)
Organism: Caenorhabditis elegans
Function: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). Binds actin but does not nucleate actin polymerization, albeit slows down elongation by blocking the barbed ends. By promoting actin depolymerization, required for the elimination of presynaptic components downstream of the egl-1, ced-4 and ced-3 apoptotic pathway during larval development.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q07171}.
Interaction partners:
- Actin
- Profilin-3
- Actin-depolymerizing factor 2, isoform c
- Conserved oligomeric Golgi complex subunit 8
- HP domain-containing protein
- Profilin-2
- Profilin-1
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 3
- Cell death protein 3
Sequence:
MGGTSLDPALAEIGKKNGLLVWRINKFVLEPVPEVDHGVFYIGDAYIALYQKYDGCWDVHFWLGKNASTDEIGVAAIKTVEIDDSLGGIPTQHREIQNYESPLFLSYFPDGIRYVSGGYESGYRHVDDQFKNWKPHLFHCKGKRNVRCTEVECEVNSLNLGDVFILDLGKDLYVWMPPESGRLERIKGMARAKNIADHERMGIPKVHILDDVEWDNDSTFWSYFGGVSSVRKVSKGKDDDDNYWKRLTEQITLWKVSDASGAAKVSMVSQGENIRKEQLDPKDAFILDAINGGIFVWIGHECTLEERSKALIWGQNYLKQHHLPRWTQVTRVLESAESTQFTQWFRDWVDEKKKNTFTPLLFQVSDESGLLHVEEIANFTQEDLDGDDVMILDALNSIYVWVGANANANEKKEALNTAKLYLEKDKLPRHKKTAIDTIFQGKEPPTFKKFFPSWDDNLFKNEVRSVQNMRRLLFH
Protein: Cysteine-rich receptor-like protein kinase 13 (Cysteine-rich RLK13) (EC 2.7.11.-) (Q0PW40)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- CDPK-related kinase 5
Sequence:
MKQRSLLSILCFILLASGVASVSAQTCIENRKYFTPNGTYDSNRRLILSSLPNNTASRDGFYYGSIGEEQDRVYALGMCIPKSTPSDCSNCIKGAAGWLIQDCVNQTDAYYWALDPTLCLVRYSNISFSGSAAFWEIEPQYLVLNTATIASNLTEFKTIWEDLTSRTITAASAARSTPSSSDNHYRVDFANLTKFQNIYALMQCTPDISSDECNNCLQRGVLEYQSCCGNNTGGYVMRPICFFRWQLFTFSKAFHNITLATTPPLSPPPLQRPVVASQPPSADNRDKKRDNSSGKISMKTILAIVVVGIVILIIISGILARRFARKEKPYQEVELNQTGITSVRSLQYKFKTIETATNNFSERLGHGGSGHVFKGRLPDGKEIAVKRLSEKTEQSKKEFKNEVVLVAKLQHRNLVRLLGFSVKGEEKIIVYEYLPNRSLDYILFDPTKQGELDWKKRYKIIGGTARGILYLHQDSQPTIIHRDLKAGNILLDAHMNPKVADFGTARIFGMDQSVAITANAAGTPGYMAPEYMELGEFSMKSDVYSYGVLVLEIICGKRNTSFSSPVQNFVTYVWRLWKSGTPLNLVDATIAENYKSEEVIRCIHIALLCVQEEPTDRPDFSIIMSMLTSNSLILPVPKPPPSFIPGRPNQSTTRPSSQNINDGRWSLLKMMFH
Protein: Transmembrane 4 L six family member 5 (Transmembrane 4 L6 family member 5) (Q6DHT3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Tetraspanin
- Integrin alpha-5 precursor
- Integrin alpha-2 isoform X1, tandem duplicate 2)
Sequence:
MCTGKCARLVGLMLLPSAFLSIIANLLLFFPNGEQLDTKNISLQVWLMGGILGGGLFMMCPSCSAIRAGGKGCCGAGCCGNRCRMLNSVFSSLFGVIGSVYCACVAIAALAVGPKCQVEGEIDWKYPFEDRKGNSSYLVDKSSWSECIFPENMVLWHIVLFSILLSLSALQAVLCVIQVVNGCVGCICGDCRKRKSDEGGL
Protein: Protein SWT21 (Synthetic With TGS1 protein 21) (P53873)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in mRNA splicing. Helps to stabilize the U1 snRNP-5' splice site interaction.
Subcellular location: Nucleus {ECO:0000269|PubMed:15020406, ECO:0000269|PubMed:19451230}.
Interaction partners:
- Protein NAM8
- U1 small nuclear ribonucleoprotein A
- H/ACA ribonucleoprotein complex subunit CBF5
- Uncharacterized protein YPL034W
- Nuclear cap-binding protein subunit 2
- Splicing factor MUD2
Sequence:
MEKKVICQDIFWSCDGTSFVSVHNDFGIRQYLVPEESNTDKLNRNLLLPFTRFFRNQSIVSCAIDPFYTLYNENSDRLAGDRIVVGGKNFPLQLYSLMDGQCILSYDTMNKINGEYETVYSVKIDVESRVYTGSCRNKVAIYDKSRRDAVWMNQSTKKASKGRQSIISCFEEQPMGGQALSRGSLLCGSYANEMFQVDCRHQRLERLNYTRTVAGGIVQILTSDNGRYVYVVRRNSDAISIYDRRNLQHELNVLRLPFRIHHNSAKLKAYIDTAYGLSMGTPQGTILNWGRDLVEFGGVPSHNSVEDPLITSIPPESEWRTNLDSTIPATVVKNCPGDPELFALSHGGTISLCRFGG
Protein: Paired box 6 (A0A1W2PSB5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ
Protein: glucan endo-1,3-beta-D-glucosidase (EC 3.2.1.39) (Q9SRT4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Beta-glucosidase 16
- Beta-glucosidase 45
- Beta-glucosidase 44
Sequence:
MSLLLHLFALSLLISVSGAKFSGRPGINYGQLGNNLPSPSDSVNLIKSLNAKRVKLYDANPKILAALNGTDITVSVMVPNELLVNISKSASLSDDWIRSNILPFYPTTKIRYLLVGNEILSLPDSELKSSLVPAMRKIQRSLKSLGVKKVKVGTTLATDVLQSSFPPSSGEFREDISGLIMKPMLQFLNRTKSFLFVDVYPYFAWAQDPTHVDLDYAIFESTNVTVTDPVSNLTYHNLFDQMIDAFVFAMKRVGYPDIRIWVAETGWPNNGDYDQIGANIYNAATYNRNVVKKLAADPPVGTPARPGKVLPAFVFALYNENQKTGPGTERHFGLLHPNGTQVYGIDLSGKTEYKESLPAPENNDLYKGKIWCVVAKGANWTQLGDALSYACSQGNNTCDPIQRGGPCQKPDLTVLHASYAFSSYWAQFRKIGGTCSFNGLATQTIKDPSYGRCEFPSVTL