wanglab/gogpt-training-data huggingface dataset:
Protein: UBP9-binding protein bun62 (Binding ubp9 protein of 62 kDa) (Q10437)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations.
Subcellular location: Nucleus. Cytoplasm. Cell tip.
Interaction partners:
- Probable ubiquitin carboxyl-terminal hydrolase 9
- UBP9-binding protein bun107
- Ubiquitin carboxyl-terminal hydrolase 11
- Mitochondrial Rho GTPase 1
- Ubiquitin carboxyl-terminal hydrolase 15
- Ubp4-interactor sfp47
- Ubiquitin thioesterase otu2
- Ubp5-interacting protein ftp105
- Probable ubiquitin carboxyl-terminal hydrolase 1
- Probable ubiquitin carboxyl-terminal hydrolase 7
Sequence:
MQTMSSGIARPVLFLTAREGEYVLKDEFQLGSSSRSTPQITGSPLDPNTPVKRLFFMRINIAQFSRWDYPYPREYIEELKKIHGVHHVEENRDVPSILENYRNSKRKSHNFSSSNTPYLKLHRPASRAGAPLINAKSFISSLTFHDNIVRSFQPSIHGKTFVFANHEKSFYWLDVSAANSHSALLKMEFPRASPVCHDINSFTKSPKGLDVIIGFDTGDVLWYDPINFKYLRFNKNGQLNSSSVTAIKWVAGKDSQFLVSFRNGWLVLYDKYRHEQPLHIVVPEKNLKSLYLSSPGTFNILISINHRDDRKLNPVACYAFSKSPINGFCFSPDYQYLALVSERGTLKLFDFVKEHVLDVFHSYFAGLTCVTWSPDGKFIAIGGKDDLVSIYSFPLRKLVARCQGHKSWVTDVIFDAWRCDDDNYRIASVGLDRKLLLWDFSVSAIHRPKSAVYYVNHHSNNSKPAISDFDDVGDLTMGSEIDNSNYVNGDITIHPTLSRSLIPVISPITIYDVDDSPLSSVFFDPDCMITCATNGRIRTWQRP
Protein: NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) (F4K0D0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MATKVYIVYYSMYGHVEKLAEEIRKGAASVEGVEAKLWQVPETLHEEALSKMSAPPKSESPIITPNELAEADGFVFGFPTRFGMMAAQFKAFLDATGGLWRAQALAGKPAGIFYSTGSQGGGQETTALTAITQLVHHGMLFVPIGYTFGAGMFEMENVKAGATASISPRPVHCQHHQEAQGIYCLELKKIMVSIRKKEKNSLVLLFFIFFLFEFGGFCDFSGLIILKYMILFHSNNSYLGFTYR
Protein: Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (Peptide:N-glycanase) (Q7KRR5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- UV excision repair protein RAD23
- UV excision repair protein RAD23
- 26S proteasome regulatory subunit 4
- Transitional endoplasmic reticulum ATPase TER94
- Derlin-1
- GM09977p
- Polyubiquitin
- GH17761p
- Ubiquitin-ribosomal protein eS31 fusion protein
- mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
Sequence:
MVDINLECVHQIEPKTRSAGQQQQERGLKEAYLEAVRILLVLLENILAQPENSMFRTIRQENKAIKEKLLSLPGCERLLEAIGFVRAPSSNAYTLPTEVSLQQVKKYRDALSERRTAWLNGTVSKSPPQQSTTSTTPLFIKPSVEYRHRIAFPRVLRTNNNFLQSLELYSDAVMQYEDNLLLATGRTLIPVEELTEMASEKLIDIQDQIASGERQEKEPCVRDLLLVELVNWFNTQFFQWVNNIPCRVCGSEESRLRRTEREGDIRVEVTVCCGQESKFYRYNDISQLLVSRKGRCGEYANCFTFLCRALDYDARIVHSHFDHVWTEVYSEAQMRWLHVDPSENVIDSPLMYQHGWKRHIDYILAYSRDDIQDVTWRYTNDHQKILHLRKLCGEKEMVQTLDAIRAKRRQNCTADRKLFLSQRNMYEVIGLTLERKPTENELKGRSSGSLSWRQSRGEHTFTNIFVFNLSATELQKRQLNVRYSCATDTYERYAKEGEHITILDSYKTWQKAQFSSKNIFRKVERDWKMAYLARLEDTDCGEIAWTFDFSKTNLKVKSYNLVFETKTFGDGKISVTVDATDGSASVENATGFKIVAKLTGGKGDVAWQHTQLFRQSLNSRDYPFDLQVQLH
Protein: Ras-interacting protein 1 (Rain) (Q3U0S6)
Organism: Mus musculus (Mouse)
Function: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy (By similarity).
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250}. Golgi apparatus, Golgi stack {ECO:0000250}. Note=Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS (By similarity). {ECO:0000250}.
Interaction partners:
- Rho GTPase-activating protein 29
- Ras-related protein Rap-1b
- Krev interaction trapped protein 1
- Cerebral cavernous malformations 2 protein-like
- Transcription factor SOX-18
Sequence:
MLSGERKEGGSPRFGKLHLPVGLWINSPRKQLAKLGRRWPSAASVKSSSSDTGSRSSEPLPPPPPPPHVELRRVGAVKAAGGASGSRAKRISQLFRGSGAGGAGGPGTPGGAQRWASEKKLPELAAGVAPEPPLPTRAAVPPGVLKIFASGLASGANYKSVLATERSTARELVAEALERYGLTGGRGAGDSGCVDAYALCDALGRPAVGVGGGEWRAEHLRVLADAERPLLVQDLWRARPGWARRFELRGREEARRLEQEAFGAADADGTNAPSWRTQKNRSRAASGGAALASPGPGSGSGTPTGSGGKERSENLSLRRSVSELSLQGRRRRQQERRQQALSMAPGAADAQMVPTDPGDFDQLTQCLIQAPSNRPYFLLLQGYQDAQDFVVYVMTREQHVFGRGGPSSSRGGSPAPYVDTFLNAPDILPRHCTVRAGPEPPAMVRPSRGAPVTHNGCLLLREAELHPGDLLGLGEHFLFMYKDPRSGGSGPARPSWLPARPGAAPPGPGWAFSCRLCGRGLQERGEALAAYLDGREPVLRFRPREEEALLGEIVRAAASGAGDLPPLGPATLLALCVQHSARELELGHLPRLLGRLARLIKEAVWEKIKEIGDRQPENHPEGVPEVPLTPEAVSVELRPLILWMANTTELLSFVQEKVLEMEKEADQEGLSSDPQLCNDLELCDEALALLDEVIMCTFQQSVYYLTKTLYSTLPALLDSNPFTAGAELPGPGAELEAMPPGLRPTLGVFQAALELTSQCELHPDLVSQTFGYLFFFSNASLLNSLMERGQGRPFYQWSRAVQIRTNLDLVLDWLQGAGLGDIATEFFRKLSIAVNLLCVPRTSLLKASWSSLRTDYPTLTPAQLHHLLSHYQLGPGRGPPPAWDPPPAERDAVDTGDIFESFSSHPPLILPLGSSRLRLTGPVTDDALHRELRRLRRLLWDLEQQELPANHRHGPPVASTP
Protein: Tb-292 membrane associated protein (Q580S2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable eukaryotic initiation factor 4A
- Elongation factor 1-alpha
Sequence:
MEEDKKHWSYDAENEGVLRDTPSPLQIQESIGNDGNTQTEGNEHGDSTTEENISNSEVKCEIEIVEKVHPDAEEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEESRLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEESRLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEESRLRAEEEARLRAEEEARLRAEEESRLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEESRLRAEEEARLRAEEEARLRAEEEARLRAEEESRLRAEEEARLRAEEEARLRAEEESRLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEARLRAEEEEARLRAEEEAHLESKDSSVKRPIQCDDGCRWIRADEVAAVSAIEGPTGSALDDCLSYSFVGISSSEVSVGGENCDAFMGKGDTSSASDNARSDHLTGRSCSKTVPLKHPLTNNIPCHDEFEICMEEELLRMGYAESDIHVRYLELHHHETSREPGRCLYPPLESGGGVLSPQNIQIGFFRSKQVVIASHSLVSRRVAKRERSAKVGERALSDSRFFFENELMSDTTVTTEDRNLPHNSPDEQLVEEQKLRTNQNNLVAAALSRFTLGDPVQVWEQACGFSLDPVPGIRDGVRQLPTHVTGETSSYIWAHEIATNKPVPAMKAFDSGVLLRVECTSIASRLLEVHKDAIDPVIVSVAFYSMGSSTKLKVSETFFFDSCVDIFYPHKERSELNRESRAMAFIPQEFFASLYLVMRVYRPCCEDQDSYVDLYSRPDRYKSQQVTLMKQNTQLLAMKSDIFEEIGWYMMPCVKNKSVVETLETTKLYQRGAPDAQVFQLVENERAQKALATLPFFASFSLKHCKGCEVEFPSQHDEPLPEENETIIKVCTRSDTEVQEETCRFVPCIIPILNSGFFNSYHNVYYFRLDRVKLVSTGILRTVPSTHRTFVMEINVRDNDTSLSGENLPLLYGNRLSAKTLQTSVWASAVHNSLDFSLSDEFKVQLPLHLGEKFHIFITLYACCKKMDNSSEEMQKMHKVGYAAFPIIHNGVVRVKDEWTIKFIAADQVLEGSEKSYLDKFSEAADEAHLNGGIPVLSVSTQTRTSVHASNAIIASLLKEMPASLESILRNDNLFRVSGNLKDIYRSDDDAIHSSLIRKMRKLPLAEILAFYPLLSFFILSLISSPSKSVSLPCRTAALEVLLDITIKTQHYDLTTRSRQKQHSARGVSKTSVTRFLYHHLTNDLLYNGEKQRLYAGFAETWLHLLVACRPHSENTDQGAGDKTAKDDREQDKRNIRKRMADLSWFLFGVILRSIYIWALENPSIPRAKLLDPGFYSIIGDLCVEALDVLDGFGIDDVLVRRTALFTRNLFNFCDRGKVLNITQRIVEFFEKRQDMEGLGTFMSIILDDVDVVTLMIPSSSYTQPVFLTRILVHAFSLLLSSPSQVVRSSSSDVLYKFICRVTNGVRYPATCLRWMASQLLALVREVSLRWKAYVQMCEKTESVATIEDKRQLCVSILWIIYYAPPGRLRNWLKGERDSDVISGLLSLVSDAQHLFRYTAGVDKANPHGVKEPTQWMREWDARMSTFVAAIGAYVCSAVLHAVPDALKSLRTEKVDPIVFPFFHLLEGVLHLGNSTAALQIGSCALLEVAHSIFPEILCSTSRMCSGMAVLVMSLMSSCSVHVRSMAEEVLFLMCYACYTGCRSVAKIKAPIFSATVYVAESKKRDLRLAGGFLELHLSNLVRKAQQSGDNFPPFSQSYVKRCEADSETPGNEVTAGRRHCGESPFTSVERMSPIPSCLISNGVNGIASLVGNRRTSAIVGSEQGSNNCNEPPSFAEELASVREISMMLFGSVRQLMQTESLRLKEAKALQHFKLAVQLLRVGAVHECLRWFQRLHELHKANNNMGEAGIVLLFVAALCFRLTEAFYQVRGKESRGARIPFIVFSHVFWHDYARLLPEVDTLLTGDVLYTVVSELRVLPSDPCLSLSGHVEVLRGAASLLDKDHYNIFSVGVLSIVERYYRLLNDFKAAASIHSAMADGCYAVSKEDRQKRENHCYFLLWARMNRAEVELHEMDGNESMQNGYSLPLKCVFKMPAKTKLEQFLECSKDFVRPLLKDATPLVVTEMAEEQKDMGALEASKLPPENCCLLSVCEVNPCFSSGRRKLTDSYDRNASLNKFEYMTYTYDNSREYGDAKPDSALLRNRLVVYKYHLERSFPSTTNVIDVATTHIDQLDTAATVAHVLGKSIEMLQAPVDNDELVGTLLRALTPGGFARPGAYIKEVITTMSTNSAVMTQVRSLSKLLKTKLTLCEKHDAPLNSTENYALVLKAVMDIECTLITLDDKVGVACSQ
Protein: Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67) (Testis leucine-rich repeat protein) (TLRR) (Q8R1Z4)
Organism: Mus musculus (Mouse)
Function: Regulates phosphatase activity of protein phosphatase 1 (PP1) complexes in the testis.
Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with alpha tubulin to the manchette of developing spermatids. Detected to nuclear rim in pachytene spermatocytes. Detected at nuclear surface, opposite the acrosome in elongating spermatids. Detected at the microtubule- organizing center (MTOC). Localized to the centrosomal region of late-stage spermatids.
Interaction partners:
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 2
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 8
- Ubiquitin-like protein NEDD8
- Ubiquitin-like protein FUBI
- Cullin-2
- COP9 signalosome complex subunit 7a
Sequence:
MVRLTVDLIAKNSNLKPRKEETLAQCLKKITHINFSDRNIDSIDDLSLCRNLSVLYLYDNRISQVTNLNYTTNLTHLYLQNNCISCIENLSSLKKLEKLYLGGNYIAVIEGLEGLEELRELHVESQRLPLGEKLLFDPRTLRSLAKSLSTLNISNNNIDDIKDLEILENLNHLIAVDNQLMHVKDLELLLKKLMKLWKMDLNGNPVCLKPKYRDKLILTSKSLEFLDGKEIKDMERQFLMNWKASKDAKKISKKRRSRSEDASNSYISNFETVHHIVPVYYPQVGKPKVIFFSDVQRYLVHGNASSKCSQEDKTTITEDIGNLSLKESESSLTKNDIHEPHLLQNPKVKENLSEKKE
Protein: Probable long-chain-alcohol O-fatty-acyltransferase 6 (EC 2.3.1.75) (Wax synthase 6) (Q9FJ77)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the final step in the synthesis of long-chain linear esters (waxes).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- 60S ribosomal L18a-like protein
- KIB1-4 beta-propeller domain-containing protein
- At5g64430
- At5g62770)
- Probable leucine-rich repeat receptor-like protein kinase At5g49770
- Homeobox-leucine zipper protein HDG7
- KH domain-containing protein HEN4
- Cytochrome P450 94B1
Sequence:
MEEELKLFIQVWVSAIISVTYCYYLTPKIKTSLLRLLSVLPVCVLFLIIPIFFSTVHSSFTIAFFLSGLAVPKLILFALEKGPLFPLPPNLPHFVCFACFPIKLQKKPNPENTNHFPKWVFALKVFIFGALLLQAYHYKQFLSTNFLLGLYALHIYLELEISLTLIKFLVSITLGCDLEPQFNEPYLATSLHDFWGHRWNLMVSKILWLAVYNPIRQWRAKSSEWDRFFAIFATFLVSGVAHEILYFYLTREKPTWEVTWFFVLHGFCMAAEVALKRKTKLVQRWPVNPAVSRLLTVGFVFVTGVWLFSPQPIRHGLMERFINEDLFLIDFFNRKLYILLGLFTSL
Protein: E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B) (Q3U319)
Organism: Mus musculus (Mouse)
Function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O75150}.
Interaction partners:
- E3 ubiquitin-protein ligase BRE1A
- Ubiquitin-conjugating enzyme E2 A
- Ubiquitin-conjugating enzyme E2 B
- RNA polymerase II-associated factor 1 homolog
- WW domain-containing adapter protein with coiled-coil
- RNA polymerase-associated protein CTR9 homolog
- Parafibromin
- Histone H2B type 2-B
- Histone H2B type 1-B
- Histone H2B type 1-P
Sequence:
MSGLSNKRAAGDGGSGPPEKKMNREEKTTTTLIEPIRLGGISSTEEMDSKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQRELSSGTEVPGCQEGLTRDVIPRPDPGTSDLREPLPVQFRAPLSEPALAFVVALGASSCEEVELQLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARVRTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLASKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCIPTLSHPDDPGLNALAPGKEDSGPGPGGTPDCKKEMALLAGATSATSSIKKEELVSSEDDAQALTPVTQGLPSRGREPEARPKRELREREGPSLGPPPAASTLSRADREKAKVEEAKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS
Protein: Vertebrate ancient opsin (A8QJE7)
Organism: Gallus gallus (Chicken)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}.
Interaction partners:
Sequence:
MDVFRALGNESLLSNSSGPARWDPFHHPLDSIQPWHFRLVAAVMFVVTSLSLAENLAVILVTFKFKQLRQPVNYVIVNLSVADFLVSLTGGTISFLANLKGYFYMGHWACVLEGFAVTFFGIVALWSLALLAFERYIVICRPVGNMRLRGKHAAQGIAFVWTFSFIWTIPPTMGWSSYTTSKIGTTCEPNWYSGAYNDRSYIIAFFTTCFIVPLLVILVSYGKLLQKLRKVSNTQGRLRTARKPERQVTRMVVVMIIAFLICWMPYAVFSILATAYPSIELDPHLAAIPAFFSKTATVYNPIIYVFMNKQVLYVLKVSSISIV
Protein: E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126) (Q91YL2)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins (By similarity). Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome (By similarity). Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targeting to the proteasome (By similarity). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (By similarity). May play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4, by mediating their ubiquitination. By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (By similarity). May monoubiquitinate AICDA (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9BV68}. Nucleus {ECO:0000250|UniProtKB:Q9BV68}.
Interaction partners:
- Large proline-rich protein BAG6
- Golgi to ER traffic protein 4 homolog
- Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Sequence:
MAEASPQPGRYFCHCCSVEIVPRLPDYICPRCESGFIEELPEETRNTENGSAPSTAPTDQNRQPFENVDQHLFTLPQGYSQFAFGIFDDSFEIPTFPPGAQADDGRDPESRREREHQSRHRYGARQPRARLTARRATGRHEGVPTLEGIIQQLVNGIISPAAVPSLGLGPWGVLHSNPMDYAWGANGLDTIITQLLNQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDYALGESVRQLPCNHLFHDSCIVPWLEQHDSCPVCRKSLTGQNTATNPPGLTGVGFSSSSSSSSSSSPSNENATSNS
Protein: Phospholipid scramblase (C9JE06)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKS
Protein: Dof zinc finger protein (Q2V4K7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00071, ECO:0000256|RuleBase:RU369094}.
Interaction partners:
Sequence:
MFGNCDQNKKMPIISSPNTNPLASMQSKNMIVASSHQQQQQQQPQQPQPQLKCPRCDSSNTKFCYYNNYSLSQPRHFCKACKRYWTRGGTLRNVPVGGSYRKNKRVKRPSTATTTTASTVSTTNSSSPNNPHQISHFSSMNHHPLFYGLSDHMSSCNNNLPMIPSRFSDSSKTCSSSGLESEFLSSGFSSLSALGLGLPHQMSHDHTINGSFINNSTTNKPFLLSGLFGSSMSSSSTLLQHPHKPMNNGGDMLGQSHLQTLASLQDLHVGGNNEDMKYKEGKLDQISGNINGFMSSSSSLDPSNYNNMWNNASVVNGAWLDPTNNNVGSSLTSLI
Protein: Transcription factor LRL3 (Basic helix-loop-helix protein 82) (AtbHLH82) (bHLH 82) (Protein DEFECTIVE REGION OF POLLEN 3) (Protein LJRHL1- LIKE 3) (AtLRL3) (Transcription factor EN 96) (Transcription factor bHLH82) (bHLH transcription factor bHLH082) (Q9LSQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that regulates the development of root hairs. Does not seem to be involved in the regulation of sperm cell development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:16581911}.
Interaction partners:
- Expansin-A7
- Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein
- At5g05960
- PHD finger protein ALFIN-LIKE 6
- Protein SEED AND ROOT HAIR PROTECTIVE PROTEIN
- COBRA-like protein 9
- Homeobox-leucine zipper protein GLABRA 2
- Peroxidase 7
Sequence:
MENGNGEGKGEFINQNNDFFLDSMSMLSSLPPCWDPSLPPPPPPPQSLFHALAVDAPFPDQFHHPQESGGPTMGSQEGLQPQGTVSTTSAPVVRQKPRVRARRGQATDPHSIAERLRRERIAERMKSLQELVPNTNKTDKASMLDEIIEYVRFLQLQVKVLSMSRLGGAGSVGPRLNGLSAEAGGRLNALTAPCNGLNGNGNATGSSNESLRSTEQRVAKLMEEDMGSAMQYLQGKGLCLMPISLATAISSSTTHSRGSLFNPISSAVAAEDSNVTATAVAAPEASSTMDDVSASKA
Protein: N(omega)-hydroxy-L-arginine amidinohydrolase (EC 3.5.3.25) (hydroxyarginase) (D2Z025)
Organism: Streptomyces lavendulae
Function: Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent. Catalyzes the hydrolysis of N(omega)-hydroxy-L-arginine (NHA) to yield hydroxyurea (HU) and L-ornithine.
Interaction partners:
Sequence:
MIDLIVSQGRVADRAAWMIEGAARTARALEERYGLKGHYVGEPAPHADDDWSVALPQARETLVAVREAATESIKGDNLTVLVNNTCSVSLATLPVVAREHPDAVVLYIDGHGDFNTPETTDTGYLGGMVLSGACGLWDSGHGAGLRPEQAVLVGSRDIDEGERELIRKAGVRVIPPGEATAQAVLDAVKDAPVWIHIDWDVLEPGSIPADYTVPDGMLPAQIRAVFEAIPAERLIGVELAELNAPADSERAEQAVAVILDMVAPAFDAAAARP
Protein: Thiol-dependent reductase 1 (EC 1.8.5.1) (Q70GE8)
Organism: Leishmania major
Interaction partners:
- As/Sb Reductase
- GST N-terminal domain-containing protein
- NADH-ubiquinone oxidoreductase 20 kDa subunit,mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH:ubiquinone oxidoreductase 78 Kd subunit-like protein
- Putative NADH-ubiquinone oxidoreductase,mitochondrial
- Mitochondrial carrier protein-like protein
- Trypanothione reductase
Sequence:
MAARALKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNAEKRFVFESMLIAQYLDNSGAPAGALMGASSAQRHQIEFFLAQVGDFIAAAHGLLRDPLSGEKRKAVDDNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPFLVRLKPALMYYAGYDVFCKAPRMKVLWAAAAQRTSVRETSPTAAQCIENYRHLVPESAPMMGANGGHVLYSNLFCPFVDRARLACELRKFQVHTVEVPLHPEPEWYKYINPRDTVPALFTPSGEAVHESQLIVQYIDCVATEGTALVPRGDAEKEYEVGFFVENAGYFVGGLMSWIIRGGEDAKAELQWAAGELEQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGGYDLFAHFPLLNVLAEAGMAAPEAKAVFRTLEEYKEHIRQRQRRAQGG
Protein: Paired mesoderm homeobox protein 2 (PRX-2) (Homeobox protein S8) (Q06348)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}.
Interaction partners:
Sequence:
MDSAAAAFALDPPAPGPGPPPAPGDCAQARKNFSVSHLLDLEEVAAAGRRAAGPVSGPAEARVGAAREPSGGSSGTEAAPQDGDCPSPGRGTKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTMSPDYLSWPASSPYSSVPPYSPGGSSPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN
Protein: F-box and leucine-rich repeat protein 11, isoform CRA_a (Lysine-specific demethylase 2A) (I3VM53)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDLELNGLESGNGDEEAVDREPRRLSSRRSVLTSPVANGVNLDYDGLGKTCRSLPSLKKTLAGDSSSDCSRGSHNGQVWDPQCAPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELANSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSEKAQKRKMEESDEEAVQAKVLRPLRSCDEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRHSPRVLVQHCPARTPQRGDEEGLGGEEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPADKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS
Protein: Possible conserved integral membrane protein (O86339)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU003943}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU003943}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Adhesion protein
- Zinc chaperone Rv0106
- Divalent metal cation transporter MntH
- Small ribosomal subunit protein bS18B
- Large ribosomal subunit protein bL28B
- Zinc uptake regulation protein
Sequence:
MLTVVCLLVVTVLAICYRPLLFATVDPEVAAARGVPVRALGIVFAALMGVVAAQAVQIVGALLVMSLLITPAAAAARVVVAPVAAIATSVVFAEVSAVGGILLSLAPGVPVSVFVATISFVIYLICWLLRRRR