wanglab/gogpt-training-data huggingface dataset:
Protein: Solute carrier family 25 member 19 (J3KS44)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGE
Protein: Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (P38444)
Organism: Rattus norvegicus (Rat)
Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P27038}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Growth/differentiation factor 11
- Inhibin beta A chain
- Bone morphogenetic protein 6
- Activin receptor type-1B
- Bone morphogenetic protein 4
- Bone morphogenetic protein 7
- Growth/differentiation factor 8
- Bone morphogenetic protein receptor type-1A
- Activin receptor type-2B
- Activin receptor type-1
Sequence:
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHMMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSGGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCLGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
Protein: Ribonuclease 2 (EC 4.6.1.19) (P42814)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May remobilize phosphate, particularly when cells senesce or when phosphate becomes limiting.
Interaction partners:
- Ubiquitin-like superfamily protein
- Autophagy-related protein 9
- Proline-rich receptor-like protein kinase PERK13
- Putative clathrin assembly protein At1g33340
- Putative clathrin assembly protein At5g65370
- Putative clathrin assembly protein At5g10410
- Equilibrative nucleotide transporter 3
- Putative clathrin assembly protein At1g14686
- Putative clathrin assembly protein At4g25940
- Putative clathrin assembly protein At5g57200
Sequence:
MASRLCLLLLVACIAGAFAGDVIELNRSQREFDYFALSLQWPGTYCRGTRHCCSKNACCRGSDAPTQFTIHGLWPDYNDGSWPSCCYRSDFKEKEISTLMDGLEKYWPSLSCGSPSSCNGGKGSFWGHEWEKHGTCSSPVFHDEYNYFLTTLNLYLKHNVTDVLYQAGYVASNSEKYPLGGIVTAIQNAFHITPEVVCKRDAIDEIRICFYKDFKPRDCVGSQDLTSRKSCPKYVSLPEYTPLDGEAMVLKMPTEREAL
Protein: Calcium-transporting ATPase (EC 7.2.2.10) (G5EFK9)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|RuleBase:RU361146}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361146}. Sarcoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004326}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004326}.
Interaction partners:
Sequence:
MIETLTSEQAASHEVVPCTHQLRTNLEEGLTTAEATRRRQYHGYNEFDVGEEEPIYKKYLEQFQNPLILLLLASAFVSIVMKQYDDAISITVAVVIVVTVGFVQEYRSEKTLEQLTKLVPPTCHVLRDGKEAMMLARELVPGDIVLLNTGDRIPSDLRIAESFSLQIDESSLTGETEPKHKETRSVPAASATGSDVEHLTCIAFMGTLVCAGRGRGIVISTAANSQFGEVVKMMMGEESPKTPLQKSMDDLGKQLSIYSFGVIAVIFLIGMFQGRNVVDMFTIGVSLAVAAIPEGLPIVVAVTLAIGVMRMAKRRAVVKKMPAVETLGCVTVICSDKTGTLTKNEMTAQAIATPEGKLAEITGIGYSAEGGVVQYQGEQVHQWTHPEFARIIEAGLVCNNATIEADKLIGQPTEGAIVVLAKKAQLEGVRSEYKRLREMPFSSDTKWMGVQCADAHGQNVYFIKGALDRVLDQCGTYYSSDNQRKQCDQYSRQHILEIGKELGQKGLRVLGLARGESMQSLMFLGMIGMMDPPRPGAADAISIVKASGVDVKLITGDAMETAQSIGQSLGILSSSDSCLSGQQVDQMSDHDLELVIRQVTVFYRASPRHKLKIVKALQALGEVVAMTGDGVNDAVALKKADIGVAMGVCGTDVCKEAADMILCDDDFSTMTAAIEEGKAIYHNITNFVRFQLSTSVAALSLIAASTMFKFDNPLNAMQILWINIIMDGPPAQSLGVEPVDDDIIRQRPRNTKQPMLTGKLIADILASAAIIVVGTLSVFYKEMSADNKVTPRDTTMTFTCFVLFDMWNALSCRSSRKMIWQIGLRRNRMFSLAVSASLICQLLVIYWAPLQHIFQTEALSLFDLIFLTTITSSVFIFNETRKYFSLRSKSLNHDPLSVSGI
Protein: Beta-phosphoglucomutase (Beta-PGM) (EC 5.4.2.6) (P77366)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the conversion of beta D-glucose 1-phosphate (G1P) to D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate (Probable). Phosphatase activity with the reaction intermediate beta-G16P has been measured. In vitro interconverts beta D-glucose 1-phosphate, beta-D-allose 1-phosphate, beta-D-galactose 1-phosphate and beta-D-mannose 1-phosphate to their corresponding sugar 6-phosphate product. The beta-D-glucose 1-phosphate substrate may be furnished by YcjT (AC P77154), the apparent upstream enzyme in the putative biochemical pathway encoded in this locus (yjcM to ycjW). It may play a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:20128927}.
Interaction partners:
- Kojibiose phosphorylase
- 3-dehydro-D-guloside 4-epimerase
- D-glucoside 3-dehydrogenase
- D-guloside 3-dehydrogenase
- Glucosylglycerate phosphorylase
- Putative ABC transporter periplasmic-binding protein YcjN
- Inner membrane ABC transporter permease protein YcjO
- Inner membrane ABC transporter permease protein YcjP
- Uncharacterized HTH-type transcriptional regulator YcjW
- Ferredoxin-like protein YgcO
Sequence:
MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESLKGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVNAVLPGIRSLLADLRAQQISVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGLGVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTESLTWPRLSAFWQNV
Protein: Ceramide kinase-like (A2AQH0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
RNTTRSEFVKHLKRHSSVKNQFNFPFVETYIIEEVKIHPKSNSNGYSPQEEGGNHTTASEHGFPWNVDGDLMEAASEVHIRLHPRLIRLYGGSLEEMNDCKVACDCI
Protein: Uncharacterized protein C14G10.04 (O74417)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized protein C1494.08c
- Uncharacterized protein C56F8.02
- Meiotically up-regulated gene 113 protein
- tRNA-aminoacylation cofactor arc1
- Uncharacterized protein C16C6.04
- Uncharacterized protein C9G1.07
Sequence:
MSQVIQYSEADLLYLSKSPLIKKPENLPEWILPEAMKADRERHIRQEKEMKRHDDDGRQYQSDRKFAKSKHDDIILGPPKLSFASSNENGRSVGRHDDLLSLGNVYNGVASLRYRNGASVSRSSSIGHSGSTAPWSSVGRHNRKKDNEHRDEMEGLEKVMKQRAGNTGPLVANSTEEFEAWKRMMKASSGEAGAGNVITPGVTSTTGAPSGKASLSRAASNSSTSARAGISVDSLFGKRSAAQAMATVVPSVSTPGGTPPRFASPALTVESMVHAAPSTTTSSRFSKFFNGLAGPETSKTSTPNMSNNPSPRVANTVVSPAPIPTIGSATIDKDAEGFQRVLAMLGRQASSTTGSPKVALSQMPQVNVNPSNQDLASVKQPSGFSPPSAVAPPPGLGNHNFSNDDSSFFRSLMTSDTRSVPPPPGFSTNAPKAVKSPEISAPPGLYRGLSSGASIPSAPPGFGYQQPSFPYSPGFPPSAYNQNRTGYGFPDTSRPPH
Protein: Reticulocyte-binding protein homolog 5 (PfRH5) (Q8IFM5)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Essential for the invasion of host erythrocytes by blood stage merozoites. By binding P113 at the surface of the merozoite and human BSG/basigin on the erythrocyte membrane, leads to the establishment of a tight junction between the merozoite and host erythrocyte membranes. In addition, the interaction with BSG results in BSG dimerization which triggers an increase in intracellular Ca(2+) in the erythrocyte. This essential step leads to a rearrangement of the erythrocyte cytoskeleton required for the merozoite invasion.
Subcellular location: Secreted {ECO:0000269|PubMed:19000690, ECO:0000269|PubMed:21909261, ECO:0000269|PubMed:25583518, ECO:0000269|PubMed:28409866}. Cytoplasmic vesicle, secretory vesicle, rhoptry lumen {ECO:0000269|PubMed:19000690, ECO:0000269|PubMed:21909261, ECO:0000269|PubMed:28409866}. Host cell membrane {ECO:0000269|PubMed:25583518, ECO:0000269|PubMed:27374406, ECO:0000269|PubMed:30542156}. Note=In late schizonts, localizes in the rhoptry lumen (PubMed:19000690, PubMed:21909261, PubMed:28409866). During merozoite invasion of host erythrocytes, secreted at the merozoite apical surface where it colocalizes with CyPRA and RIPR at the interface between the merozoite and the erythrocyte (PubMed:19000690, PubMed:21909261, PubMed:25583518, PubMed:27374406). {ECO:0000269|PubMed:19000690, ECO:0000269|PubMed:21909261, ECO:0000269|PubMed:25583518, ECO:0000269|PubMed:27374406, ECO:0000269|PubMed:28409866}.
Interaction partners:
- Cysteine-rich protective antigen
- Rh5-interacting protein
- Reticulocyte-binding protein homolog 1
- Reticulocyte-binding protein 3
- Reticulocyte-binding protein homolog 2b
- Apical membrane antigen 1
Sequence:
MIRIKKKLILTIIYIHLFILNRLSFENAIKKTKNQENNLTLLPIKSTEEEKDDIKNGKDIKKEIDNDKENIKTNNAKDHSTYIKSYLNTNVNDGLKYLFIPSHNSFIKKYSVFNQINDGMLLNEKNDVKNNEDYKNVDYKNVNFLQYHFKELSNYNIANSIDILQEKEGHLDFVIIPHYTFLDYYKHLSYNSIYHKSSTYGKCIAVDAFIKKINETYDKVKSKCNDIKNDLIATIKKLEHPYDINNKNDDSYRYDISEEIDDKSEETDDETEEVEDSIQDTDSNHTPSNKKKNDLMNRTFKKMMDEYNTKKKKLIKCIKNHENDFNKICMDMKNYGTNLFEQLSCYNNNFCNTNGIRYHYDEYIHKLILSVKSKNLNKDLSDMTNILQQSELLLTNLNKKMGSYIYIDTIKFIHKEMKHIFNRIEYHTKIINDKTKIIQDKIKLNIWRTFQKDELLKRILDMSNEYSLFITSDHLRQMLYNTFYSKEKHLNNIFHHLIYVLQMKFNDVPIKMEYFQTYKKNKPLTQ
Protein: Probable Ras GTPase-activating-like protein ngap (DdNGAP) (Q54Y08)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May function as a Ras GTPase-activating protein.
Interaction partners:
- PH and Rap-GAP domain-containing protein DDB_G0271806
Sequence:
MMESLTVNENTINEFEIKNDIIIEQQQIQSKTSIPLLNIKDGNTTTTNTINEINNNNNNIETSTMSRKSLMTPSATYESLIRQQKTKDCNLTVKVFEARNLIEARLRKREMVKNGKSFKRAQNLLTEISSPNLMTFSDTTDPYCTVQLEKQKQRTRTIPKKLNPFWCEEFQLEISDPASAKLVLSVMDEKKYSNDEHIGKLVIPINTLKDQKERELWFPLTQPQSSKKVPQIQILFNFKPISLTDPSQPGHIQWKVLFGRNLSHSLATPLPSMSAASMGGSTSTENISNVYTNTTPFINWSVRSKKGDIVIDEEGIAWQDALTNGITRELKDSIECITFTLWRYEPKTFSDDGDISGLKSPRGTNSSASGSGFIPSTPPPSSHQKSNDTTATTTPSSTPSTPISPSSQSNNIKTPDSKTRSSSNASTNTPQTTPKSTGTSGGPAPPETINLSSSINSTSSLISNGSINVIDSSNNLHHHHNNGTNIMNPLKDGYEQYFIGQGIVLASHIDIEKPNDQWLCLYPKQTLDNKFGDIRLKLKYSEEVVLPLQSYQPLLELLQQENLYTITLLGKVTKHRESVSNNLIRVFEKTGKCLYLLKSLTDHEIDSTNNPDIIFRGNSLATKSVDLFMKLIGIPYLSQTIGPLIKKIYSSKKSCEIDPTKLEKGEDIKKNCKNLLSWVKKMTTAILSSVNNCPGPLREVFKSIQDKVVQRYPKDEITRYTAVSGFIFLRFFCPAILAPKLFDLMPDHPGIKTTRSLILIAKTLQNLANQVEFGEYKEDFMKDMNRFVIDNMENMKSFINTLSTVPADCPPGALQSPIILEKELACLYRHLIKQRQDMAEEMESTESEPKTQQEKDSFGKLIKILNSLDEDVQLASN
Protein: Mitotic spindle organizing protein 2B (A0A494C0V9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}.
Interaction partners:
Sequence:
MAAQGVGPGPGSAAPPGLEAARQKLALRRKKVLSTEEMELYELAQAAGGAIDPDVILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQDPAAVSLPTSSVPETRGRNKGSAALGGALALAERSSREGSSQRMPRQPSATRLPKGGGPGKSPTRGST
Protein: R86 (Serine (or cysteine) peptidase inhibitor, clade B, member 9b) (Q9DAV6)
Organism: Mus musculus (Mouse)
Interaction partners:
- Cathepsin G
- Albumin
- Thyroglobulin
- T-cell surface glycoprotein CD4
- Interleukin-4
- Granulocyte-macrophage colony-stimulating factor
- Interleukin-5
- Interferon gamma
- Interleukin-13
- H-2 class II histocompatibility antigen, A beta chain
Sequence:
MSTLSEANGTFAIHLLKMLCQSNPSKNVCFSPVSISSALAMVLLGAKEQTAVQISQALGLKKEKGIHQGFLKLLRKLNKPDRKYSLIVANRLFADKTCEVLQTFKESCFRFYDSEMEQVNFFKAAVESRQCINTWVSKQTEGKIPELLADDSVNFQTRLVLVNALYFKGMWACQFCKESTREMPFYINKDEKRPVQMMCQTDTFMFAFVDELPARLLIMPYEGMELSLMVLLPEKGVDLSKVENDLTFEKLIAWTKPDIMWSTEVKVFLPKFKLQEDYEMKSVLQCLGIVDVFEKEKADLSAMSPERNLCLSKFIHKSVVEVNEEGTEAAAASSAEGIIPLCLGGGPSWFCADHPFLFFIRHNQTNSILFCGRFSSP
Protein: Swarming motility protein SwrB (P40405)
Organism: Bacillus subtilis (strain 168)
Function: Required for swarming motility and for maximal sigma-D activity.
Interaction partners:
- Flagellar biosynthetic protein FliZ
- RNA polymerase sigma-D factor
- Flagellar FliJ protein
- Flagellar biosynthetic protein FlhB
- CheY-P phosphatase CheC
- Flagellar biosynthesis protein FlhA
- Chemotaxis protein CheW
- Flagellar biosynthesis protein FlhF
- Negative regulator of flagellin synthesis
- Chemotaxis protein CheA
Sequence:
MSTLLWLLSFMLHGVLLYAVIILYTRLAAVKETEKQQKQILEETENTLAAFLLELKEENEKLIENKASSASQSDEESQKSGLQTSETYQERDPVQEAENLPEHIEGLITEVDRREELVNSEVQSFEDQVIELYEQGYSASQIAQKMKSGKTEIELFLKFRSKGVKDS
Protein: Nicotinamide nucleotide adenylyltransferase 3 (A0A8I5ZNV6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHGELLRSVAQMDGPDPSKIPSASAALPELKLLCGADVLKTFHTPNLWKDSHIQEIVEKFGLVCVNRSGHDPKRYILDSPILQQFQHNIHLAREPVLNEISATYVRKALSQGQSVKYLLPEAVITYIRDQGLYINDSSGKGKGKTG
Protein: Pluviatolide O-methyltransferase (PhOMT3) (EC 2.1.1.323) (A0A0N9HMN6)
Organism: Sinopodophyllum hexandrum (Himalayan may apple) (Podophyllum hexandrum)
Function: O-methyltransferase involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family. Catalyzes the methylation of (-)-pluviatolide to produce (-)-bursehernin.
Interaction partners:
Sequence:
MEMAPTMDLEIRNGNGYGDSGEELLAAQAHIYNHIFNFISSMALKCAVELNIPEILHNHQPKAVTLSELVQALQIPQAKSACLYRLLRILVHSGFFAITKIQSEGDEEGYLPTLSSKLLLKNHPMSMSPCLLGLVNPTMVAPMHFFSDWFKRSDDMTPFEATHGASLWKYFGETPHMAEIFNEAMGCETRLAMSVVLKECKGKLEGISSLVDVGGGTGNVGRAIAEAFPNVKCTVLDLPQVVGNLKGSNNLEFVSGDMFQFIPPADVVFLKWILHDWNDEECIKILKRCKEAIPSKEEGGKLIIIDMVVNDHNKGSYESTETQLFYDLTLMALLTGTERTETEWKKLFVAAGFTSYIISPVLGLKSIIEVFP
Protein: Trinucleotide repeat containing adaptor 6A (H7C269)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
QQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMERNPYFDKNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM
Protein: Uroplakin-1a (UP1a) (Uroplakin Ia) (UPIa) (P38572)
Organism: Bos taurus (Bovine)
Function: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Uroplakin-2
- Uroplakin-1b
- Uroplakin-3a
- Uroplakin-3b
- Keratin, type I cytoskeletal 20
- Tetraspanin-31
Sequence:
MASAAAATTEKGSPVVVGLLVMGNIIILLSGLALFAETVWVTADQYRIYPLMGVSGKDDVFAGAWIAIFCGFSFFVVASFGVGAALCRRRSMILTYLILMLIIYIFECASCITSYTHRDYMVSNPSLITKQMLTFYSADSNQGRELTRLWDRIMIEQECCGTSGPMDWVNFTSAFRATTPEVVFPWPPLCCRRTGNFIPVNEEGCRLGHLDYLFTKGCFEHIGHAIDSYTWGISWFGFAILMWTLPVMLIAMYFYTTL
Protein: Mucin glycoprotein MUC3 (O35419)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
ADVTTTADVTTTIDVTTTADVTTSAEVTTTADVTTTTEVTTTTEVATTPEPTTTPAPTTTAVNCMNGGFWTGDKCICPNGFGGDRCENIVNVVNCENGGTWDGLKCQCTSLFYGPRCEELVESVEIEPTVAASVGVSVTVTSQEYSEKLQDRKSEEFSNFNKTFTKQMALIYAGIPEYEGVIIKNLSKGSIVVDYDVILKAKYTPGFENTLDTVVKNLETKIKNATEVQVQDVNNNCSALLCFNSTATKVQNSATVSVNPEETCKKEAGEDFAKFVTLGQKGDKWFCITPCSAGYSTSKNCSYGKCQLQRSGPQCLCLITDTHWYSGENCDWGIQKSLVYGLGGAGVAVLLVILVILLVFSIRFRKDAQRQRSRVSEMYKWGEEEGRASPGTFHNFGFDHNEERENYMPLDSVYNTFQPSLNHINPERKIQIQRPQVVMTSL
Protein: Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (mOSCAR) (Ocl178) (Q8VBT3)
Organism: Mus musculus (Mouse)
Function: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- High affinity immunoglobulin epsilon receptor subunit gamma
- TYRO protein tyrosine kinase-binding protein
- Tyrosine-protein kinase SYK
- Transcription initiation factor IIA subunit 2
- Cytokine receptor common subunit gamma
- High affinity immunoglobulin gamma Fc receptor I
- Dendritic cell-specific transmembrane protein
- Low affinity immunoglobulin gamma Fc region receptor III-A
- Low affinity immunoglobulin gamma Fc region receptor III
- Tumor necrosis factor ligand superfamily member 11
Sequence:
MVLSLILQLSTLWPACRADFTPTAPLASYPQPWLGAHPAAVVTPGINVTLTCRAPQSAWRFALFKSGLVTPLLLRDVSVELAEFFLEEVTPAQGGSYHCRYRKTDWGPGVWSQPSNVLELLVTDQLPRPSLVALPGPVVAPGANVSLRCAGRIPGMSFALYRVGVATPLQYIDSVQPWADFLLIGTHTPGTYCCYYHTPSAPYVLSQRSQPLVISFEGSGSLDYTQGNLIRLGLAGMVLICLGIIVTCDWHSRSSAFDGLLPQQN
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (Q8ILV1)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Cleavage and polyadenylation specificity factor subunit 3, putative
- WD repeat-containing protein 82, putative
- Protein phosphatase inhibitor 3
- Protein phosphatase inhibitor 2
- Autophagy-related protein
Sequence:
MALEIDIDNVISKLIEVRGTRPGKNVNLTENEIKILCLSSREIFLNQPILLELEAPIKICGDIHGQFYDLLRLFEYGGFPPDANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYSVKLWKTFIDCFNCLPVAAIIDEKIFCMHGGLSPELNNMEQIRKITRPTDVPDNGLLCDLLWSDPEKEINGWGENDRGVSFTFGQDVVHNFLRKHELDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPVEKKKAAN
Protein: Iron-sulfur cluster assembly protein SufA (P77667)
Organism: Escherichia coli (strain K12)
Function: Member of gene cluster sufABCDSE that mediates iron-sulfur cluster assembly under oxidative stress and iron limitation conditions. Binds [2Fe2S] cluster by mobilizing sulfur atoms provided by the SufS-SufE cysteine desulfurase system and then transfers the assembled Fe-S cluster to target proteins including ferredoxin and aconitase. Seems to act as a Fe-S cluster carrier rather than a scaffold, this role being performed by SufB and SufC.
Interaction partners:
- Iron-sulfur cluster assembly protein SufD
- Probable ATP-dependent transporter SufC
- Iron-sulfur cluster assembly protein SufB
- Cysteine desulfurase
- Cysteine desulfuration protein SufE
- Co-chaperone protein HscB
- Iron-sulfur cluster assembly scaffold protein IscU
- Chaperone protein HscA
- Cysteine desulfurase IscS
- 2Fe-2S ferredoxin
Sequence:
MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV
Protein: histidine kinase (EC 2.7.13.3) (Q1D8M1)
Organism: Myxococcus xanthus (strain DK1622)
Subcellular location: Cell envelope {ECO:0000256|ARBA:ARBA00004196}.
Interaction partners:
- histidine kinase
- histidine kinase
- Sensory/regulatory protein RpfC
- histidine kinase
- Response regulator
- Response regulator/chemotaxis protein CheW
- Response regulator/GGDEF domain protein
- histidine kinase
- Response regulator DotR
- histidine kinase
Sequence:
MNPPSTSPGDRWRPDGGGLFTARRWARLERLPPRFIAIRPNASSQDAAGCIARLRKITPPPCTPTDRVKQLTSQTELPVPGGELGELLRSHDWSRTQLGPYESWPRPLKAFVTMILEMPAPAIIFWGHELIQVYNDGYAVIMGPRHPRYLGATYRECWPDTYPVISPWMRKLLATGEVTQVAKTYFMLTRYGFNEEAYFTFDFSPLRDDAGTIAGILQVVFEVTDVVLSERRLATIRALAPRVNGPSESATTDAIRALADNPKDIPFALIYHWDEGEQRLELAESTGLDGLAQHAVVDLGRITEATKQAVAANVPVLLESVPSLLGARQFGPWPEPTEKALVLPLRRTRTDSLRGVVVLGISPRLRFDDTYRQFFEDLARELATHLAVEQEKRAEREAYTHAKQARAQAEAEVARRAQAEAALRASEERLRMALAAGQLGVVELQYERGVLSWDERALQHLGLPPGKSPTLKEAAARIHPDDVNRARRTIEQALRPGAEAIRLECRVQGWDGVQRFLLAMVKTHFDAQGQPDRVVGALQDVTEQRSAERERERLATIVEQSPDFIGVGDPSGRAVWVNDAGRRLLGLGLDEDITRYHLRDFFLAEDQTYVDEHIAAAILQGGRREGAFRFRHFPTGEPIAAQYHTFALVEHDTQRQMGIATVGRDIRAQKRLEAERERLLARERVAREEAEEANRLKDEFLATVSHELRTPLTAVLGWVQMLRTGTLPPEKRERALATVERNARAQGQLVEDLLDVSRIMTGKLKLDVSSVDVSQVVEAVLESLRPAAEAKGIRIQAALDSGGTIMGDVSRLQQVVWNLLSNAVKFTPKGGRVQVLVERRNSSVEITVADTGQGISPQFLPHVFERFRQADGSTTRKAGGLGLGLAIVRHLVELHGGTVMATSEGEGRGATFIVSLPQAVALRREVLVPPTLRGPLQEQDIPCPPQLASLRVLVVDDEEDTRELLRSIIEACGGIVTTASSSEDALAELREASFDVLVSDVGMPEEDGYRFIARVRALPEEQGGGIPAVALTAYTRMEDRTRALLAGFTTHVPKPIEPVELMAVIASMSNRGPPRRA
Protein: ER membrane protein complex subunit 6 (O59764)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- ER membrane protein complex subunit 3
- ER membrane protein complex subunit 4
- ER membrane protein complex subunit 1
- TPR repeat protein oca3
- UPF0620 protein C83.10
- ER membrane protein complex subunit 5
- Uncharacterized membrane protein C660.17c
Sequence:
MERDKGVAPIVVENVAYNEQVVSFVRNLTSSFFGCAAGILGLTSYEGLALYVLGYFFVSFLLFALKMRGNLTKYYQPGYKFWIAKILDGAPSYVLTWTLFYSLVYVYE
Protein: Ca(2+)/H(+) antiporter (SynCAX) (P74072)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Plays an important role in salt tolerance. Does not transport sodium or lithium.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:14559898}; Multi-pass membrane protein {ECO:0000269|PubMed:14559898}.
Interaction partners:
Sequence:
MSTKSKIFLVLLVFCPLSFAAHWLGWGETTVFILAGLAIVPLAAFMGTATEEIAVVIGPNAGGLLNATFGNATELILAYIALKEGLIEVVKATLTGSIIGNLLLVMGFAVFLGGLRYKEQNFQPLAARLNASTMNLGVVAILLPTALQYTSTGVEETVLQNLSVAVAVVLIGVYLLSLVFSMGTHAYLYDVGVAENMEMPELGEDVSEPEPPTEEEKPNLWLWTGVLLVVTLGVAVESELLVGSLEVATESLGLTALFTGVIVLPIIGNAAEHATAVTVAMKDKMDLSMSVVMGSSLQIAFFVAPVLVIVGWAIGQPMDLNFNPFELVAVLVAVLIVNSISSDGTSNWLEGILLLATYAIVALAFFFHPTLV
Protein: VAN3-binding protein (Protein FORKED 1) (Q8W4K5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- ADP-ribosylation factor GTPase-activating protein AGD3
- Ras-related protein RABA1c
- Type IV inositol polyphosphate 5-phosphatase 6
- Protein DETOXIFICATION 40
- E3 UFM1-protein ligase 1 homolog
- ADP-ribosylation factor GTPase-activating protein
- Vacuolar protein sorting-associated protein 51 homolog
- ADP-ribosylation factor
- Phototropic-responsive NPH3 family protein NPY4
- ADP-ribosylation factor GTPase-activating protein AGD7
Sequence:
MERELRRPNPINSSRRPEIFSSGGSSTQLPESPRGPMEFLSRSWSVSALEVSRALHTAKSASATNRPPSSINTPIPEETLNPEKEECPPENSTSVSSQFSFAASATSQLVLERIMSQSEVSPLTSGRLSHSSGPLNGGGSFTETDSPPISPSDEFDDVIKYFRTHNTIHPLFSGTGGSRGTTGNGSNTPMAGTGPKTVGRWLKDRKEKKKEETRTQNAQVHAAVSVAAVASAVAAVAAATAASSPGKNEQMARIDMAMASAAALVAAQCVEAAEIMGADRDHLTSVVSSAVNVKSHDDIVTLTAAAATALRGAATLKARALKEVWNIAAVLPAEKGASSALCGQVDTKHSDSSFSGELPVAGEDFLGVCNQELLAKGTELLKRTRGGELHWKIVSVYINKAGQAVLKMKSKHVGGTFTKKKKHMVLEVRKDIPAWAGRDLFNGDKHHYFGLKTETKRVIEFECRNQREYEIWTQGVSRLLAIAAEKKQKSSMSKWMAP
Protein: Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP) (Q9H3G5)
Organism: Homo sapiens (Human)
Function: May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.
Interaction partners:
- Beta-chimaerin
Sequence:
MVGAMWKVIVSLVLLMPGPCDGLFRSLYRSVSMPPKGDSGQPLFLTPYIEAGKIQKGRELSLVGPFPGLNMKSYAGFLTVNKTYNSNLFFWFFPAQIQPEDAPVVLWLQGGPGGSSMFGLFVEHGPYVVTSNMTLRDRDFPWTTTLSMLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLIHSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPEDQLYYVKFLSLPEVRQAIHVGNQTFNDGTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTERSLMGMDWKGSQEYKKAEKKVWKIFKSDSEVAGYIRQAGDFHQVIIRGGGHILPYDQPLRAFDMINRFIYGKGWDPYVG