wanglab/gogpt-training-data huggingface dataset:
Protein: 2'-5'-oligoadenylate synthase 1A ((2-5')oligo(A) synthase 1A) (2-5A synthase 1A) (EC 2.7.7.84) (p42 OAS) (P11928)
Organism: Mus musculus (Mouse)
Function: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15899864}. Mitochondrion {ECO:0000250|UniProtKB:P00973}. Nucleus {ECO:0000250|UniProtKB:P00973}. Microsome {ECO:0000250|UniProtKB:P00973}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P00973}. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions. {ECO:0000250|UniProtKB:P00973}.
Interaction partners:
- Antiviral innate immune response effector IFIT1
- Interferon-induced, double-stranded RNA-activated protein kinase
- Interferon regulatory factor 7
- Ubl carboxyl-terminal hydrolase 18
- Interferon-induced protein 44
- Ubiquitin-like protein ISG15
- Interferon-induced helicase C domain-containing protein 1
- 2'-5' oligoadenylate synthase
- 2-5A-dependent ribonuclease
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
Sequence:
MEHGLRSIPAWTLDKFIEDYLLPDTTFGADVKSAVNVVCDFLKERCFQGAAHPVRVSKVVKGGSSGKGTTLKGKSDADLVVFLNNLTSFEDQLNRRGEFIKEIKKQLYEVQHERRFRVKFEVQSSWWPNARSLSFKLSAPHLHQEVEFDVLPAFDVLGHVNTSSKPDPRIYAILIEECTSLGKDGEFSTCFTELQRNFLKQRPTKLKSLIRLVKHWYQLCKEKLGKPLPPQYALELLTVFAWEQGNGCYEFNTAQGFRTVLELVINYQHLRIYWTKYYDFQHQEVSKYLHRQLRKARPVILDPADPTGNVAGGNPEGWRRLAEEADVWLWYPCFIKKDGSRVSSWDVPTVVPVPFEQVEENWTCILL
Protein: Mitochondrial ribosomal protein S2 (RE59650p) (Q8MSS7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein bS6m
- Mitochondrial ribosomal protein S11
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS9m
- 28S ribosomal protein S14
- Small ribosomal subunit protein uS10m
Sequence:
MLRKSFANLPRFGQMCGLPRRLQSTQPEQSVETEPEDIALVEQRILKHPDYFQVHNLFTVRDLFNARVHYGHKEGSLDDRMRPYLFGSRLGHLIFDLDKTASHLRDALNFAAHIAFRDGIILFFNRNAMNSHLVERKAQEAGEFSHTRFWRGGIFTNANVQFDAVTRLPDLCIFLNTQNNVMAQHTAVRDAAKMAIPTIGIVDSNCNPNLITYPVPGNDDSPAAVELYCNLFKEAILRGKRERRQLLGLPPLDESQPRRSRKTK
Protein: RNA binding protein, putative (Q57XU8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- G-patch domain-containing protein
- Probable eukaryotic initiation factor 4A
- PHD finger-like domain-containing protein 5A
- U2 small nuclear ribonucleoprotein B, putative
- Splicing factor 3B subunit 1, putative
- Sm protein F
- Splicing factor 3A, putative
- SURP motif domain-containing protein
- RNA helicase
- RNA helicase
Sequence:
MPNSDHSYSYGYGYSGSRGGSNSAGAKRERSTSPKGSHNRHYHHGSYHRYRDSDSGRSYHSGRSGDEPQYVIAASAPCLQVPSDLPVDVAAFIDLVAFYIVQGGPTAEEEIMRREANNHHFAFLRGTWKDPQQLYYRWRLYSLLQGDTLLKWRTEPFQIERGKDAYAWIPPPPISSGPECLLGACTGGPRETKGKPTDGSGRSSNASAVGAARPQPSALWLSRMCVSEGTYFVALGKEEVEKWEKLLSMDHIVEELGGVATTSTTTTTAPPSSSSTAGSSATCCGMTLEERIGKLAASLLNGERIAERMVFAVEHQKAALHLMSFILDEVVRLAYASADAARGNGNTNTTVAARTGSCSSGGNSCRNPAFLAAARCCMCLSYLFTLNDIGRNGGAHPLLDEDVANMVASHGGHQGGGANKPAGSGNNSRGTSADPSLVPPASVLANTSARGPLPLMPLPNTAVITPTAASHSVRALNRAVEKIMPTLIEATLLVALNTVRQYGSLQVVKALDADKNEEKPPGVEGTEGILPMGTDHTAHLHVQARISTTAVSADVMDLRKEDRDAVCMIGLLLLSWLKQLCSSWSDGDVIGSRCWSTLASKYNFLVSQTIETT
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q57X39)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MHILKFATLIAAAVIATAGADKQSKNRADCTDPCTCMARIDVALNRLEGAMPQTLQKIASNAAYMSELQMAAGSTDAELAKLVQPLLAVAIDVQQDATTDLPTASKTISETLNALTQRKALFEAIKKLSGTYDGSIITKTSGHFGTAQYTAAPIVAVQREPCPKLSGTEEYTYDELNFDHGQGIGLPQLAIELDQACYKNTEGTPCDANDGSDKLKTKIKFGTKHGPAGTSPLANGRFATTVQGTINLSNETAADNKKKLSKAAAADAKLTNIPDLSKRETYTSHPAFSLLVNRLLMSTAPTVEITGQVATATEAFINKNYGSDQEQFKAKIWDKIKTATTVYYENKAKKTKKVSALSGDQKVTALPAAFFKEQKETTTTKKETAEDAPKKTDTEDKKGEKKDGDKTSGESFSSYQTKDACEAVNKDGKKHCGWKRKVIATPKRIKKPAQTVVFSSIKKLALCVAAAFVSILVF
Protein: GDSL esterase/lipase At5g33370 (EC 3.1.1.-) (Extracellular lipase At5g33370) (Q8LB81)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Acetyl-CoA:benzylalcohol acetyltranferase-like protein
- At1g62510
- GDSL esterase/lipase At5g62930
- Probable lysophospholipase BODYGUARD 3
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- At2g10940/F15K19.1
- CHY-type/CTCHY-type/RING-type Zinc finger protein
- Probable inactive patatin-like protein 9
- Non-specific lipid transfer protein GPI-anchored 31
Sequence:
MTNSVAKLALLGFCILQVTSLLVPQANARAFLVFGDSLVDNGNNDFLATTARADNYPYGIDFPTHRPTGRFSNGLNIPDLISEHLGQESPMPYLSPMLKKDKLLRGANFASAGIGILNDTGIQFLNIIRITKQLEYFEQYKVRVSGLVGEEEMNRLVNGALVLITLGGNDFVNNYYLVPFSARSRQFSLPDYVVFVISEYRKVLRKMYDLGARRVLVTGTGPMGCVPAELAQRSRNGECATELQRAASLFNPQLIQMITDLNNEVGSSAFIAANTQQMHMDFISDPQAYGFVTSKVACCGQGPYNGIGLCTPLSNLCPNRDLFAFWDPFHPSEKASRIIAQQILNGSPEYMHPMNLSTILTVDSMT
Protein: Communication mutant protein F (Q557B8)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MKIYKKNHFLKILIIFIYLSCNILKVNADGTFSTIQPSTDIKFDKSNLEFVAEWDVSANSISNVVGSTDSSEFSLNYGVWGPTYNYLIAKNKSPSIKANVDYTFSFDFKLGKALGEYNNYQSMVLSFYIPEDIAYFPWEIRTPLYTTNEFSGNFASTSYQSKILTFRSTVDIGNSIMVLRINRATETGPTASSVYFRNMKITIPSKPITTPTDLLTKDSELIVIPKPPISLDLQDLTKCPYLTASDLYNWHDPTIWPNGVVPSPNQNITIPAGKRVLISASSISQTQIYSRIVVPVNSELIFNDQNFTMNIRDIYVQGKFIMGTSLCRYNSFINIIFHGEKTLQDTIAQFYGSKGIAVASGGFISVQGKQYHNTWSKLASNVWSGDRVIWIQDNVNWEVGQQVLITTSVYKDELDNQNEILTIKAIEGKKIEFTEPIKWFKYGSQEYQSEVALLSRRIVFSSDESSSVSTSFGGHILSSGEMQFAGVQLKRMGQKNVKARYPLHYHLGGTLNNSFISDCSVTNSYYRCYTIHGTNNVTLTRNVAYDAFGHCYYLEDGVEVDNRISFNLGAYVHTIGKPAAGASQIGETFYQSSELTQPADSAASCFYITNSWNSFIGNAASGGWAGFAFPNLPKPIGNHRTLNIIPMQYPIKEWQGNTAHSSGYYFEDGASIYVGGNLTFNEANGMLIYNSGRLGRTTYVNGVKNENNVVFDRLNNTKIFLSNLGVGYWGENIEIVGYESHDNTRPVSLFGNVWLHNALVNGQSGNILTKNSETTRQGFRFYDFYVQTIISNTIFRNFIHSTAATKRDEDNVVITATTFSDVFKPQFISATKNITFQNVPQSQIIGHEDVANSGSSRLFNFLDGDGSVTSSFTGKPGIPQIVGSHVSWWKFDDSCLFSTEWNVWVCNKGTKGLANIEFWVPGFMERELEQDPDSYIGSISLFGSGINDERKTLLTRNPGITGVSNMGWYAYFTIGTPNYLRIWTAQIAFGEYIFLAIPYPTGTTFTITSEYDYSNQYTYTITKTTSALAVKQGNGKQYYFDGTHLFLKLVNFMNTGGSWESFDRVGIKIPDVYWTYIYNIRATNTAKPSVNGYFLNLPDVRPSSTL
Protein: Achromobactin siderophore NIS synthase (E0SIF3)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Interaction partners:
- Achromobactin siderophore NIS synthase
- Diaminopimelate decarboxylase
- 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
- Achromobactin-binding periplasmic protein
- Putative AcsD
Sequence:
METLSPVVLQDIACDWLPHMDAQRYQLVEQRVVGQLLQTLLYEDVLPYRRTPIGDGNSQFAITGRDARQVPVEYRCNGLFSDSFDLIRLDYASVRRIGPDGDAQSPNLHQMLEELLGEQESNPFLTRFVQELEQTQLKDLQSRAQDYQPGKPAHQLSFDQLERHFMDAHSYHPCYKSRIGFSLQDNAQWGPEFGQPFAIVWLALAKPLASANHSSKLDLDDFLQTEFGAARWQAFSEQLARQGRKAQDYQLIPVHPWQWKNVIAPVFYPELVSGELIYLGASDDRWQAQQSIRTLANVTEKTRPYVKLAMSMTNTSSTRILARHTVMNGPIITDWLQQLIDTDQTARNLKFVILGEVAGVSFDTQPLPATRMAQAYGVMGAIWRESIHQYLQLDEQAVPFNGLSHVEHRYDGGEQAPFIDAWIRQYGLEAWTRQLLEVTVSPIIHMLYAEGIGMESHGQNIVLVVRDGWPQRIALKDFHDGVRYSPDHLARPAMRPDLVPLPASHAKINRNSFILTEDVNAVRDFTCDSFFFICLAEMAIFLRRHYQLPEARFWEMTAEVVLRYQAEHPQHRSRYSLFDVFAPTYEVEELTKRRLLGDGERRFKSVPNPLHPFRPSSC
Protein: UDP-glucuronosyltransferase 1A6 (UGT1A6) (EC 2.4.1.17) (Phenol-metabolizing UDP-glucuronosyltransferase) (UDP-glucuronosyltransferase 1-6) (UDPGT 1-6) (UGT1*6) (UGT1-06) (UGT1.6) (UDP-glucuronosyltransferase 1-F) (UGT-1F) (UGT1F) (P19224)
Organism: Homo sapiens (Human)
Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity).
Subcellular location: Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- UDP-glucuronosyltransferase 1A9
- UDP-glucuronosyltransferase 1A3
- UDP-glucuronosyltransferase 1A1
- UDP-glucuronosyltransferase 1A8
- UDP-glucuronosyltransferase 1A4
- UDP-glucuronosyltransferase 1A10
- Cytochrome P450 3A4)
- UDP-glucuronosyltransferase 1A7
- UDP-galactose translocator
- Cytochrome P450 1A1
Sequence:
MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
Protein: Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (Na(+)-dependent ileal bile acid transporter) (Solute carrier family 10 member 2) (Q7T3A9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Gastrotropin
- Transmembrane and immunoglobulin domain-containing 1.
- ATP-binding cassette, sub-family B
- Sodium/bile acid cotransporter 7
Sequence:
MCTLEPVCPVNATICTGTSCLVPRDPFNDILSVVMSVAITVMLAMVMFSMGCTVEARKLWGHVRRPWGIFIGFLCQFGIMPFTAFILSLLFNVLPVQAVVIIIMGCCPGGSSSNVFCYWLDGDMDLSISMTACSSILALGMMPLCLLIYTTIWTAGDAIQIPYDNIGITLVSLLVPVGLGMLVKHKWPKAAKKILKVGSVVGIVLIIVIAVIGGVLYQSSWTIAPSLWIIGTIYPFIGFGLGFLLARFVGQPWHRCRTIALETGMQNAQLASTITQLSFSPAELEVMFAFPLIYSIFQLVVAGIAVSIHYSIKRCRHQTLVEEDGEGTTEDCDKHSYSLENGGFSCDENGNNQNKDKGTKL
Protein: Nucleolar protein SWM2 (Synthetic With MUD2-delta protein 2) (P40342)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Trimethylguanosine synthase
- Splicing factor MUD2
- U1 small nuclear ribonucleoprotein component PRP42
- Uncharacterized membrane protein YGL140C
- Pre-mRNA-splicing factor CWC21
Sequence:
MIDLYNYSNLEGLLDGLTDLNRIPKEYSAVLEPYFQNIARNAHLKSRALKICRSNFHKWNEEGAKTVNPEIIRRCLNLWYVLKGKEYKKLKDPPPADNIIKDEIDVSYVKNLNVVRLEFDEFGKLISNPLENLILEEVEVNDFIQE
Protein: Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase (EC 2.4.2.43) (4-amino-4-deoxy-L-arabinose lipid A transferase) (Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase) (Polymyxin resistance protein PmrK) (Undecaprenyl phosphate-alpha-L-Ara4N transferase) (P76473)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
- Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
- Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
- Bifunctional polymyxin resistance protein ArnA
- Phosphoethanolamine transferase EptA
- UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase aminotransferase)
- Lipid A palmitoyltransferase PagP
- Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF
- Lipid A 1-diphosphate synthase
- Kdo
Sequence:
MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPNFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK
Protein: Probable CCR4-associated factor 1 homolog 9 (EC 3.1.13.4) (Q9LXM2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- Transcription regulator
- Probable NOT transcription complex subunit VIP2
- Cell differentiation, Rcd1-like protein
- Cell differentiation, Rcd1-like protein
- Cell differentiation, Rcd1-like protein
- RNA binding
- RNA binding
- Carbon catabolite repressor protein 4 homolog 1
- Transcription regulator NOT2/NOT3/NOT5 family protein
- NOT2 / NOT3 / NOT5 family
Sequence:
MAIIKPNRDLKPDGVTVVTREVWAENLESEFELISEIIDDYPFISMDTEFPGVIFKSDLRFTNPDDLYTLLKANVDALSLIQVGLTLSDVNGNLPDLGDDLHRGFIWEFNFRDFDVARDAHAPDSIELLRRQGIDFERNCRDGVESERFAELMMSSGLVCNEEVSWVTFHSAYDFGYLMKILTRRELPGALGEFKRVMRVLFGERVYDVKHMMKFCERRLFGGLDRVARTLEVNRAVGKCHQAGSDSLLTWHAFQRMRDLYFVQDGPEKHAGVLYGLEVF
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q9LUK3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSKQTPNLESLQDCSSSNYNNANASPVSGSASFKTSSNGSEDVRLNNSISLSFCSSNSVSSEANLEKTQSFDANEANFKRVFAPSKPHKGNDLRWDAIQNVKCSKNEDLGLGHFRLLKKLGCGDIGSVYLAELREMGCFFAMKVMDKGMLIGRKKLVRAQTEREILGLLDHPFLPTLYSHFETEKFSCLLMEFCSGGDLHILRQKQPGKHFSELAARFYASEVLLALEYLHMMGVVYRDLKPENVMVREDGHIMLSDFDLSLQSFVSPTLIQSTSQPSCHIASYCIQPPCIDPSCKLPVACIQPSCFKPRFLNNKPRKAKTEKAGSDSLPMLIAEPTAARSMSFVGTHEYLAPEIIRGDGHGSSVDWWTFGIFLYELLTGKTPFKGNGNRETLFNVVGQPLKFPEGSISFAAKDLIRGLLTKDPKKRLGFKKGATEIKQHPFFNNVNWALIRSTTPPEIPKPIDLSILNETLKSSVQQQGKHSKQSDSSSGPYLDFEFF
Protein: Chelated iron transport system membrane protein YfeD (Q56955)
Organism: Yersinia pestis
Function: Part of an ATP-driven transport system YfeABCD for chelated iron.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Chelated iron transport system membrane protein YfeB
- Iron-binding protein YfeA
- Chelated iron transport system membrane protein YfeC
- Zinc import ATP-binding protein ZnuC
- High-affinity zinc uptake system protein ZnuA
- Divalent metal cation transporter MntH
Sequence:
MNMLFSLISEPFAYPFMQRAIVAAIVTGVVCAILSCYLVLKGWSLMGDAISHAVLPGIVLAFWLGIPLVIGAFVSGIFCAVATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRIDTDQHLSHILFGNMLGISLTELKQTLWIAGFTLLVVLLKRKDFMLYCFDPNHARVIGLPVKFLHYGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMICRSFDQMLVVATLVSVVACVLGTLISFHIDGATGPCIVIIQALFFVVALIYNHIKPIKDRKMAPLTKAVNPENTAPSNLP
Protein: Probable peptidoglycan muropeptide transporter SLC46 (Solute carrier family 46 member) (A1Z7R6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasmic vesicle, phagosome membrane {ECO:0000305|PubMed:28539433}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized protein, isoform A
- Oligopeptide transporter 1
Sequence:
MNEEPHAHENLVAKAQRSGDADPEVASTASEKQRSSGASAIAVGTEFPGNPQASRPQSLGMYLLEPFILILLFAYNFSSTVLKNEVIYQSCTAGFGYPDSVCQLLGTKNITNETKRIEEQVQPYAAQVTLAMRLVECFIPAFCGLFAGSWADHYGRKPLLMCSFLGYGLQYLISAAIAYCAMYTQGLVSPWWYVLSIVPLSCLGSSVTYSVAAVCFIADVSGGKVRSYRMIAYELAIYVGLLLGSLGSGYAYEATDAYIVFSISAVCIFTALFLMALLLPESLPARNRTLSTPTTDTSVVSMLKSLWSTCSKPREHQNRFMLTTIMVVLLLTAFVSDGSNSVFYKFMRIKFHWTVKQFTEYETVGILVPAVAGSGGVLFIWSLRKCTNSAILWLALVSLLSHCSSSLMKGFALESWQIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTLYVAIYTRTLNTEPGIFNVFSAFLFGIGIILLGTVWHKKSRNLVYYEPVFK
Protein: Protein NLP3 (AtNLP3) (NIN-like protein 3) (Nodule inception protein-like protein 3) (Q9SVF1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00852}.
Interaction partners:
- MOB kinase activator-like 1B
- Putative MOB kinase activator-like 2B
- MOB kinase activator-like 2A
- Protein RKD3
- Protein RKD1
- Protein RKD2
- Rop guanine nucleotide exchange factor 14
- Protein RKD5
- Transcription factor HRS1
- MOB kinase activator-like 1A
Sequence:
MVGPFKKILHAHNQRFPPSSSSSLDPVVDDSSRKQTRIILSYLLHLSLSLHITYSLCLLHFFFGSSNPFSPMEESNNSAVVDFPDNFMDQLLWEECWEEEATQHDQALSSPSGLKERVACAMGHLQEVMGERELLIQLWVPVETRSGRVLSTEEQPYSINTFSQSQSLALYRDASAGYSFAAEVGSEQLVGLPGRVFLRRMPEWTPDVRFFRKEEYPRIGYARRYQVRATLALPLFQGTSGNCVAVMEMVTTHRNLEYASQLSTICHALEAFDLRTSQTSIVPASLKVTSSSSSSSRTEVASILQGICSSHGLPLAVTWGHQDSSSCLSALISASYAADHGSRCFLAACSEHHLLGGEGIAGRAFATKKQCFATDVAIFSKWSYPLSHYAKMFDLHAALAVPILTRGNRTVQFVLELFFPRDCLDIQTHSLTLASQLKLRFQSSPHLMVDDNQIAEEVRDAATPPLTQEDPKGKQVSFSFSSASSLENRKRKTKAEKDITLDTLRQHFAGSLKDAAKNIGVCPTTLKRICRQNGISRWPSRKIKKVGHSLRKLQVVMDSVEGVQGSLHLASFYSSFPQLQSSSSSSFPFINPTQTVHVPPKSPPSSSGSQSSSGSSTCCSSEEQQLGGFQKPALSHPQLLTLSSMHEDQRPVRVTSSLPPLPSATTPRKAKDGMKVKAMFGDSMLRMSLLPHSRLTDLRREIAKRFGMDDVLRSNFSLKYLDDDQEWVLLTCDADLEECIQVYKSSSLKETIRILVHHPLSRPSFGS
Protein: Glutamate dehydrogenase 1, mitochondrial (EC 1.4.1.3) (Q8JHY0)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
VEGFFDRGANIVEDKLVEDLKNKETPVQKRHRVRGILKIIKPCNHILSVSFPIKRDDGEWEVIEGYRAQHSQHRTPCKGGIRYSTEVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINVKNYTDNELEKITRRFTIELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYANSMGHHDINAHACVTGKPISQGGIHGRISATGRGVFHGIENF
Protein: Methyl-CpG-binding domain-containing protein 13 (AtMBD13) (MBD13) (Methyl-CpG-binding protein MBD13) (Q9LTJ8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcriptional regulator.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Methyl-CpG-binding domain-containing protein 3
- Methyl-CpG-binding domain-containing protein 1
- Methyl-CpG-binding domain-containing protein 5
- Methyl-CpG-binding domain-containing protein 6
- Methyl-CpG-binding domain-containing protein 7
- Putative methyl-CpG-binding domain protein 12
- Methyl-CpG-binding domain-containing protein 8
- Methyl-CpG-binding domain-containing protein 11
- Methyl-CpG-binding domain-containing protein 2
- Methyl-CpG-binding domain-containing protein 10
Sequence:
MNGEGISDGLSAERKVEIRVRKNGRKDKVIVEKSAAQGLPEGWIKKLEITNRSGRKTRRDPFFIDPKSEYIFQSFKDASRYVETGNIGHYARKLKESDIEDDDSGNGKTVLRLEYVDKRSADDVLEKEKTIDDVRRSKRRNLSSSDEHSKNCKMTSDLSIVTSQVLEDLGKKEEVKDPIEKQLIAKRVTRSQTKASTTEEVVVDLKRNLSSSNAKSEKDSVNSSVRSQKPKKEAVMKEEEEQDSSEKRITRSKVEEKKNELSNSVARRTSKRLAGIELEPTPELKTRAKVQRIVPLDDEPTPELKTRTKVQRVVPPDDEPTPELKTRTKIQRIVPPDDEPTLELKTRTKVQRILPPDDELTPELKSRTKVQRIVPPDDELTPEFKTRTKVQQRIPPDDGRAGKCKQPVNHVTTSGSKKTEIPLNKEVAQSCNEQSSQKPHAAAATSNNRVSADSAVGIQNIGKAVGRKPSKDKKTLKSPLIVYELNPVFHLDGYKQKEEMSPVSPLSCQTSATKCEKTAAGKRVGRSSPKANLTTSVKPTQISPLRSPNKGKQPHPSDSGSAIQRRNKLANEYSNSSVVRGTCSEVMEKSTNSFSSAFDSTLADLCKDPCIAFAIKTLTGESLCLLNTPAISSNPINNHTKQKGVSFTPETPGNVNTCSEKLVFPSPPPGANIWQDPCIDFAIKTLTGAIPIGLDEPDTKSKSQGMTSTTAATQEAKGRQNNCDYMTNKTVGKPDDLRFTQSFSKD
Protein: Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) (P15848)
Organism: Homo sapiens (Human)
Function: Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity).
Subcellular location: Lysosome {ECO:0000250|UniProtKB:P50429}. Cell surface {ECO:0000250|UniProtKB:P50429}.
Interaction partners:
- Alpha-L-iduronidase
- Arylsulfatase A
- Formylglycine-generating enzyme
- Arylsulfatase G
- Hyaluronidase-1
- Hyaluronidase PH-20
- Hyaluronidase-2
- Hyaluronidase-4
- Hyaluronidase-3
- Arylsulfatase K
Sequence:
MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM
Protein: Transcriptional regulator, LysR family (Q9K1H8)
Organism: Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Interaction partners:
- Cell division topological specificity factor
- Septum site-determining protein MinD
- Probable septum site-determining protein MinC
Sequence:
MTLTELRYIVAVAQERHFGRAARRCFVSQPTLSIAIKKLEEELAVSLFDRSSNDIITTEAGERIVAQARKVLEEAELIRHLANEEQNELEGAFKLGLIFTVAPYLLPKLIVSLRRTAPKMPLMLEENYTHTLTESLKRGDVDAIIVAEPFQEPGIVTEPLYDEPFFVIVPKGHSFEELDAVSPRMLGEEQVLLLTEGNCMRDQVLSSCSELAAKQRIQGLTNTLQGSSINTIRHMVASGLAISVLPATALTENDHMLFSIIPFEGTPPSRRVVLAYRRNFVRPKALSAMKAAIMQSQLHGVSFICD
Protein: HECT-type E3 ubiquitin transferase (EC 2.3.2.26) (Q382A4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Polyubiquitin, putative
- Ubiquitin-like modifier-activating enzyme 5
- E3 ubiquitin-protein ligase
- Ubiquitin-conjugating enzyme E2, putative
- Ubiquitin-conjugating enzyme E2, putative
- Ubiquitin-conjugating enzyme E2, putative
- E2 ubiquitin-conjugating enzyme
- Ubiquitin-protein ligase, putative
- Ubiquitin fusion degradation protein 2, putative
- E2 ubiquitin-conjugating enzyme
Sequence:
MEHILSRLMMDAEGGGLQRQAMKDVITARENLASNDEARVTTGLLELCDLLNMATPITIGSIRPNVFVPLVVNCMKKDNIDLVILAARALTYMVDAISSTVFVLVSEGGIDVLLQHFQEVKDIELSEQCLTCVEKITQNSVCAATVLQSMGVPALLMYVDFFNAASQRKAWTSVAAMCRRVNESNFGCVECSLQDISARIDHDDAKISEKAITCLYRIISGVGSNPELVARAFGDSCNPLISVLSRQDLSETTFTTALSLIACAIDCSTEAARRTLESGIVEYMFTLIASSSEQQQRQDLAGFAGRTDGVSRASAAREPSAQRESVETVPQRDRRLSVEQTKALCLALTALLPKLNKGYLVHGDALNKLIAEGHGESHRHAGASSSEADEGMGGDDDEDGDGDMDDDDDEEEEEECTHEEILSRVSERGILLENNEKYRTCRLRHMCDGCGKSCIPTSWFRCNKCRDYDLCGRCLLMNWDSHSPDGETHSFCDMLVFFPKVSDSVTPEEGKESNNSDLTAERERLYESNPHLLALILGGIPTVVALFNESEAHLVRNHCLAFIDRAVVLATPEQLAGIKGLSEAALCEMIVTAMVDSSLILNVQVMYLCRMLLEKLPKVYLPCFVHEGVTNSLVKIQEQNKSFVHCSEEPTPVKEPPSSERFNSVSGWRELLATEAEEMLGMFTSLSDDTRILRLKEVDRLLRGGKLKEAFDSLRVALLDETTAFELSATDVLHSLVEALKSVDDVKAIVALLKTLAKQEPNTTSTLTRFVRLLQTALSHLDQFQLPNFGAVNTIQTQIPLRLVPHVAGHAPKPKASTPPAKGNASKRVASGSTAGPPVPTREVVTRRPTGTSAARPAAVTSRNKKDQSASPASTNTGGGKSSVENREVRVSVEPLTNLEALMGFVGSNVLSGGGEFIGSPVTGGGRRRNDDDEVEEVLPELANGVDPEGLPKKKKPVQEKSCRPVYMRCGKYVLPPSLTILQLLQRYHTPSQSSSRKRKAHSKGASASLRLLALLEGMQTNVGDMITLHYSVDPFGPEYVHVPALIDVPLGTPAHPVEIKLPSDDITPPGAFEVMRALHNEYPFSSQFLTVAQKDILTLLGILHAALRNWSALISSTAEATTSGGVSDEASAPSTSLGEFIHGKLNNKAMRHCSNLLLAGQHMTTWAVNLALDCNFLFSSMTRKYLFDVGFCGSIRSLVQMQENMEKYGMRDTLNADHQFVRSYRLQREKKRVWRDKALACAMHIMGKERISGSVVLEFEYYNENGSGSGPTMEFYTLVSDELRETKLRLWRRTDETPDDKYYRPHVGVYPRPIPPSSPELDDMERYFSLLGRLIARALLDKRILSIPLSPVLLKMLRGDPCGVHDLADISESLGASVLAIARAARRGDGAVQMPNSTVMCSVEDLGLDFTLPGDEFVELTEGGASIPVTKVNAMEYCDAVTEFVLRRGVERFVHALRTGFHDYVPLYALRMLSIGELFEVLNGHPARVTVEELDANCQADHGYTMGCRHVRQLFEIIASLTEKEQSAFFHFLTGSAHLPAGGLASLRPKFTIVRKASSDPNVREQDQLPSAMTCQNYLKLPAYDTKQQMEEKLKIAINEGCGEFLLT