wanglab/gogpt-training-data huggingface dataset:
Protein: Small ribosomal subunit protein uS9y (40S ribosomal protein S16-2) (Q9M8X9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein uS17z
- Large ribosomal subunit protein uL23y
- Small ribosomal subunit protein eS6y
- Small ribosomal subunit protein uS13z/uS13y/uS13x
- Small ribosomal subunit protein eS10y
- Small ribosomal subunit protein uS12z
- Small ribosomal subunit protein eS28z/eS28y
- Small ribosomal subunit protein eS12z
Sequence:
MATQPAKESVQCFGRKKTATAVTYCKRGSGMIKLNGSPIELYQPEILRFKIFEPVLLLGKHRFAGVDMRIRATGGGNTSRVYAIRQSIAKALVAYYQKYVDEQSKKEIKDILMRYDRTLLVADPRRCESKKFGGPGARARFQKSYR
Protein: proton-translocating NAD(P)(+) transhydrogenase (EC 7.1.1.1) (Q72GR8)
Organism: Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Interaction partners:
Sequence:
MVTVAVPKERAPGERRVALVPEVVARLVKGGARVRVERGAGEGAYHPDEAYQEAGAEVVERGELLKGAHLLFTVQPPPEDLIQALEPGAIVVGFVQPHKNLELVRALQAKKATVIAMELIPRITRAQSMDALSSQATVAGYLAAIHAARLSPRFFPMLTTAAGTIRPAKVMVMGVGVAGLMAIATAKRLGAQVFAYDVRKAALEQALSLGAKPIELPISAEGEGGYARELTEEEKRIQHEALRDHVAGMDVLITTAQVPGRRAPILLTEDMVERLKPGTVVVDLAAESGGNCVLTKPGEVVEVRGVRVYGPLNLPSELSVHASEMYAKNLYNLSSLLIEKGAFAPKWEDEIVRAALLMKEGEVLHGPTKALLGGA
Protein: Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2) (Q9H5Q4)
Organism: Homo sapiens (Human)
Function: S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Stimulates transcription independently of the methyltransferase activity.
Subcellular location: Mitochondrion.
Interaction partners:
- DNA-directed RNA polymerase, mitochondrial
- Transcription factor A, mitochondrial
- Bystin
- Pre-rRNA-processing protein TSR1 homolog
- Protein LTV1 homolog
- Serine/threonine-protein kinase RIO2
- Periodic tryptophan protein 2 homolog
- Uncharacterized protein.
- Ribosome biogenesis protein BRX1 homolog
- Transcription termination factor 1, mitochondrial
Sequence:
MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
Protein: Protein IQ-DOMAIN 2 (AtIQD2) (Q93ZH7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity). May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:28115582}.
Interaction partners:
- Protein KINESIN LIGHT CHAIN-RELATED 1
- Protein NETWORKED 3C
- Protein NETWORKED 4A
- At5g61865
- Mitochondrial import inner membrane translocase subunit PAM16 like 2
- Tryptophan aminotransferase-related protein 4
- Tryptophan aminotransferase-related protein 3
- Mitochondrial import inner membrane translocase subunit PAM16 like 1
- Mitochondrial import inner membrane translocase subunit TIM44-1
- Mitochondrial import inner membrane translocase subunit TIM44-2
Sequence:
MGKKAKWFSSVKKAFSPDSKKSKQKLAEGQNGVISNPPVVDNVRQSSSSPPPALAPREVRVAEVIVERNRDLSPPSTADAVNVTATDVPVVPSSSAPGVVRRATPTRFAGKSNEEAAAILIQTIFRGYLARRALRAMRGLVRLKLLMEGSVVKRQAANTLKCMQTLSRVQSQIRARRIRMSEENQARQKQLLQKHAKELAGLKNGDNWNDSIQSKEKVEANLLSKYEATMRRERALAYSYSHQQNWKNNSKSGNPMFMDPSNPTWGWSWLERWMAGRPLESSEKEQSNSNNDNAASVKGSINRNEAAKSLTRNGSTQPNTPSSARGTPRNKNSFFSPPTPSRLNQSSRKSNDDDSKSTISVLSERNRRHSIAGSSVRDDESLAGSPALPSYMVPTKSARARLKPQSPLGGTTQENEGFTDKASAKKRLSYPTSPALPKPRRFSAPPKVESGGVTVTNGAGS
Protein: H/ACA ribonucleoprotein complex subunit 2 (Nucleolar protein family A member 2) (Q38F38)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU366039}.
Interaction partners:
- Bms1-type G domain-containing protein
- Nucleolar RNA binding protein, putative
- U3 small nucleolar ribonucleoprotein protein MPP10, putative
- Uncharacterized protein
- Nucleolar protein 56
- AATF leucine zipper-containing domain-containing protein
- Uncharacterized protein
- Small ribosomal subunit protein uS4
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 15 C-terminal domain-containing protein
Sequence:
MTAEISEKAFPLAGDRLTQTILDIVQEASNAKMIKKGANEATKALNRGIADLIVLAGDTNPIEILLHLPLLCEDKNVPYVFVPSKTALGRAAQVSRNAVALAILQMENSPISAKIQAVKLEIERLL
Protein: Kinesin-like protein KIF9 (Q9WV04)
Organism: Mus musculus (Mouse)
Function: Essential for normal male fertility and for progressive motility of spermatozoa.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:32072696}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000305|PubMed:32072696}.
Interaction partners:
- Kinesin-associated protein 3
Sequence:
MGTRKKVQAFVRVRPTDDFAHEMIKYGEDNKSIDIHLKKDTRRGVVNNQQTDWSFKLDGVLHNASQDLVYETVAKDAVSQALDGYNGTIMCYGQTGAGKTYTMTGATENYKHRGILPRALQQVFRMIEERPTHAITVRVSYLEIYNENLFDLLSTLPYVGPSVTPMTIVENPQGIFIKGLSVHLTSQEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYMEAHSRTLSDEKYITSKINLVDLAGSERLSKTGSEGRVLKEATYINKSLSFLEQAIIALGDQNRDHVPFRQSKLTHALKDSLGGNCNMVLVTNIYGEAAQLDETLSSLRFASRMKLVTTEPAINEKYDAERMVKNLEKELALLKQELAIHDSLSNRTLVNYDPMDEIQIAEINSQVRRYLEGTLDEIDIINLRQIQEVFNQFRVVLSQQEQEVESALRRKYTLIDKNDFAAISAVQKVGLMDIEGNLVGEPDGQSFGLGVAPFSVKPGKKPKTKKTPKDQFSSSARKEGASSPVSGKDFDVASISKTQLIPSSKDGDLKDMLARERETSSIEPLISDSPKEELRAPRPSTPPSRTVAFEEFKNERGSEINRIFKENKSILNERKKRASETTQRINAIKQEIDETKDALNFQKSLREKQGEYENKGLMIIDEEEFLLILKLKDLKKQYRNEYQELRDLRAEIQYCQRLVDQCRHRLLMEFDIWYNESFMIPEDVQVALKLGSSIRPGMVPISRIVCLGEDDQDRFSHLQQTVLPEGLDSITFYNAKVKTDQKHNYMKTMVGLQQSHRK
Protein: Ig heavy chain V region 3-6 (Ig heavy chain V region M315) (P18531)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MKVLSLLYLLTAIPGILSDVQLQESGPGLVKPSQSLSLTCSVTGYSITSGYYWNWIRQFPGNKLEWMGYISYDGSNNYNPSLKNRISITRDTSKNQFFLKLNSVTTEDTATYYCAR
Protein: Serine/arginine-rich SC35-like splicing factor SCL30 (At-SCL30) (AtSCL30) (SC35-like splicing factor 30) (Serine/arginine-rich splicing factor 30) (Q8L3X8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in intron recognition and spliceosome assembly (Probable). Probably active at the 5' splice sites.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:15133128}.
Interaction partners:
- Serine/arginine-rich splicing factor RS31
- Serine/arginine-rich splicing factor RS2Z33
- Serine/arginine-rich splicing factor RSZ21
- Serine/arginine-rich splicing factor SR30
- Serine/arginine-rich splicing factor SC35
- Serine/arginine-rich-splicing factor SR34
- Serine/arginine-rich SC35-like splicing factor SCL30A
- Serine/arginine-rich SC35-like splicing factor SCL28
- Glycine-rich RNA-binding protein RZ1B
- Eukaryotic translation initiation factor 2 subunit alpha homolog
Sequence:
MRRYSPPYYSPPRRGYGGRGRSPPPPPPRRGYGGGGGGGGRRGSSHGSLLVRNIPLDCRPEELREPFERFGPVRDVYIPRDYYSGQPRGFAFVEFVDAYDAGEAQRSMNRRSFAGREITVVVASESRKRPEEMRVKTRTRSREPSGSRDRSHGRSRSRSISRSRSPRRPSDSRSRYRSRSYSPAPRRRGGPPRGEEDENYSRRSYSPGYEGAAAAAPDRDRNGDNEIREKPGYEAEDRRRGGRAVSRSPSGSRSRSVEVSPR
Protein: Disease resistance protein RPS5 (Resistance to Pseudomonas syringae protein 5) (pNd3/pNd10) (O64973)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Disease resistance (R) protein that specifically recognizes the avrPphB type III effector avirulence protein from Pseudomonas syringae. Also confers resistance against Hyaloperonospora parasitica (downy mildew). Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Requires PBS1 to trigger the defense reaction against avrPphB. In case of infection by Pseudomonas syringae, AvrPphB triggers RPS5-mediated defense mechanism via the cleavage of PBS1, suggesting that the cleavage of PBS1 could trigger an exchange of ADP for ATP, thereby activating RPS5. May function as a fine-tuned sensor of alterations in the structure of the effector target PBS1.
Subcellular location: Cell membrane; Lipid-anchor {ECO:0000269|PubMed:22046960, ECO:0000269|PubMed:22331412}.
Interaction partners:
- Serine/threonine-protein kinase PBS1
- Lysine-specific demethylase JMJ29
- Disease resistance protein
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
Sequence:
MGGCFSVSLPCDQVVSQFSQLLCVRGSYIHNLSKNLASLQKAMRMLKARQYDVIRRLETEEFTGRQQRLSQVQVWLTSVLIIQNQFNDLLRSNEVELQRLCLCGFCSKDLKLSYRYGKRVIMMLKEVESLSSQGFFDVVSEATPFADVDEIPFQPTIVGQEIMLEKAWNRLMEDGSGILGLYGMGGVGKTTLLTKINNKFSKIDDRFDVVIWVVVSRSSTVRKIQRDIAEKVGLGGMEWSEKNDNQIAVDIHNVLRRRKFVLLLDDIWEKVNLKAVGVPYPSKDNGCKVAFTTRSRDVCGRMGVDDPMEVSCLQPEESWDLFQMKVGKNTLGSHPDIPGLARKVARKCRGLPLALNVIGEAMACKRTVHEWCHAIDVLTSSAIDFSGMEDEILHVLKYSYDNLNGELMKSCFLYCSLFPEDYLIDKEGLVDYWISEGFINEKEGRERNINQGYEIIGTLVRACLLLEEERNKSNVKMHDVVREMALWISSDLGKQKEKCIVRAGVGLREVPKVKDWNTVRKISLMNNEIEEIFDSHECAALTTLFLQKNDVVKISAEFFRCMPHLVVLDLSENQSLNELPEEISELASLRYFNLSYTCIHQLPVGLWTLKKLIHLNLEHMSSLGSILGISNLWNLRTLGLRDSRLLLDMSLVKELQLLEHLEVITLDISSSLVAEPLLCSQRLVECIKEVDFKYLKEESVRVLTLPTMGNLRKLGIKRCGMREIKIERTTSSSSRNKSPTTPCFSNLSRVFIAKCHGLKDLTWLLFAPNLTFLEVGFSKEVEDIISEEKAEEHSATIVPFRKLETLHLFELRGLKRIYAKALHFPCLKVIHVEKCEKLRKLPLDSKSGIAGEELVIYYGEREWIERVEWEDQATQLRFLPSSRWRWRET
Protein: Interleukin-5 receptor alpha chain (Q99PS3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MVPVLLILMGASATLHADLLSPEKFLLLPPVNFTIKATGLAQVLLHWDPNPDQDPVDLEYHVKINVPQEDEYDTKNTESKCVTPLHECFAASVRTILKSIHSPLASSWVSAELKAPPGSSGTSVMNLTCTTNTVKSSHTHFRPYQVSLRCTWLVGKDAPEDTQYFLYYRFSVWTEECQEYSRDALNRNIACWFPRTFINSKGFEQLAVHINGSSKHAATKPLDQLFTLYAIDQVNPPMNVTVEIENNSLYIQWGKPLSAFPVHCFKYKLKIYNTKNGYSQMENLVTNKFISKIDDVSTYSIQVRAAVSSPCRMSGSWGEWSQPIYVGKKKKPLVEWHLIVLPTAICFILLIFSLICRVYHLWTRLFPPVPAPKSSIKDLPVVTEYEKPPWNETKIEIVHFVEEDGFEVMENSLF
Protein: Cyclin (Q382C9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Protein artemis
- Cyclin 6
Sequence:
MTIMMDGPKSSTRATETINQSDGQHRQQWCDRQQTGRNCNSAGSDSQSADPQQSGLHELGQLTAVAVERRCVEQRHLEHLYQSAFHSSHVPAISVWNYMRRIGKYSRCSPECFIICIIFIDRYVAATNCPITFRNIHRLLITSMLVSVKLRDDSFYSNSYFAGIGGVSNEELNRLEIEFLMTIDWRTWVEPSDFNMYCEQLRSRCSANQEQ
Protein: Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14 homolog) (Q9D1C9)
Organism: Mus musculus (Mouse)
Function: Nucleolar protein that is involved in ribosomal RNA (rRNA) processing. Also plays a role in primary cilia resorption, and cell cycle progression in neurogenesis and neocortex development.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9Y3A4}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9Y3A4}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9Y3A4}.
Interaction partners:
- Nucleolar protein 6
- WD repeat-containing protein 46
- Protein RRP5 homolog
- KRR1 small subunit processome component homolog
- U3 small nucleolar RNA-associated protein 4 homolog
- BMS1 homolog, ribosome assembly protein
- WD repeat domain 36
- U3 small nucleolar RNA-associated protein 18 homolog
- WD repeat-containing protein 43
- Transducin beta-like protein 3
Sequence:
MVSRRKKRKAGGHEESIPSPPGYSAVPVKFSAKQQAPHYLYMRQHRVRQGTQSTWPPDRTLFILNVPPYCTQESLSRCLSCCGTIKTVELQEKPDLAESPTEPKSQFFHPKPVPGFQVAYVVFQKPSGVSAALNLKGPLLVSTESHLVKSGIHKWISDYEDSVLDPEALRMEVDAFMEAYDKKIAEEEAKAKEEEGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLEKEKRKRARKELLNFYAWQHRETKMEHLAQLRKKFEEDKQRIELMRAQRKFRPY
Protein: Retinol dehydrogenase 14 (EC 1.1.1.300) (Alcohol dehydrogenase PAN2) (Q9ERI6)
Organism: Mus musculus (Mouse)
Function: Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol. Shows a very weak activity towards 13-cis-retinol. Has no activity towards steroids.
Interaction partners:
Sequence:
MAVASVAAALLAALGGALWLAARRFSGPRNQRQQGGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK
Protein: Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2) (P29460)
Organism: Homo sapiens (Human)
Function: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Subcellular location: Secreted.
Interaction partners:
- Interleukin-12 subunit alpha
- Interleukin-23 subunit alpha
- Interleukin-12 receptor subunit beta-1
- Interleukin-23 receptor
- Interleukin-12 receptor subunit beta-2
- Immunoglobulin heavy variable 3-43D
- Interferon gamma receptor 1
- Interleukin-2 receptor subunit alpha
- Non-receptor tyrosine-protein kinase TYK2
- Protein disulfide-isomerase
Sequence:
MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCS
Protein: Fcr3p (A0A1D8PN91)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- very-long-chain enoyl-CoA reductase
Sequence:
MNFKTENSTTPNGDWSQSKAFTNSGSSFPVLNGTCELDQENLALSNSGQPESIFTQDSGLHGIDVAAPSDITDLNNQSGYQYNNNLAHDLYFTGSMEMPTTQHPYITNTNNHLSYSNSSEEFSPIGNNMSPDSTGGANSNNFTSGNKRKASNESFSPLSGHHYGTESGNNNNNNGTSRSSQYSSHKSRKKLLDEKDAALIARDDSELTEEELQMKRKAQNRAAQRAFRERKESKLKELEAKLLASEEERQKLLDELEQIKKQNISIATENEILKHNGMGNINNDVQIGNLSSYGRLQVDKFNFPKTQKDFIEHVLQGTNHQLKDENKDKVYNDNQGHKLLALGAVWDYLQIKAEEADLDFNSIDFNDVMEKLKGNEKCHGYGPAYPLELVNEAIESSLN
Protein: Glucan 1,3-beta-glucosidase BGL2 (EC 3.2.1.58) (Exo-1,3-beta-glucanase) (Q5AMT2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Cell wall glucan 1,3-beta-glucosidase involved in cell wall biosynthesis and virulence. Crucial for delivery of beta-1,3-glucan to the biofilm matrix and for accumulation of mature matrix biomass. Plays a role as a major antigen in human systemic candidiasis patients.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:19013773}. Cytoplasm {ECO:0000269|PubMed:19013773}. Note=Tightly bound to cell wall. A fraction of unprecessed protein is found in the cytoplasm.
Interaction partners:
- Glucan 1,3-beta-glucosidase
- Glucoamylase 1
- Glucoamylase 1
- beta-glucosidase
- 1,3-beta-glucan synthase
- beta-glucosidase
- 1,3-beta-glucan synthase
- 1,3-beta-glucan synthase
- glucan 1,3-beta-glucosidase
- Glucan 1,3-beta-glucosidase 2
Sequence:
MQIKFLTTLATVLTSVAAMGDLAFNLGVKNDDGTCKDVSTFEGDLDFLKSHSKIIKTYAVSDCNTLQNLGPAAEAEGFQIQLGIWPNDDAHFEAEKEALQNYLPKISVSTIKIFLVGSEALYREDLTASELASKINEIKDLVKGIKDKNGKSYSSVPVGTVDSWNVLVDGASKPAIDAADVVYSNSFSYWQKNSQANASYSLFDDVMQALQTLQTAKGSTDIEFWVGETGWPTDGSSYGDSVPSVENAADQWQKGICALRAWGINVAVYEAFDEAWKPDTSGTSSVEKHWGVWQSDKTLKYSIDCKFN
Protein: THO complex subunit 2 (F1M0V4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAATVVVPAEWIKNWEKSGRGDFLHLCRILSENKSHDSSTYRDFQQALYELSYHVIKGNLKHEQASSVLNDISEFREDMPSILADVFCILDIETNCLEEKSKRDYFTQLVLACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAELGQDLSGTITSDLILENIKSLIGCFNLDPNRVLDVILEVFECRPEHDDFFISLLESYMSMCEPQTLCHILGFKFKFYQEPSGETPSSLYRVAAVLLQFNLIDLDDLYVHLLPADNCIMDEYKREIVEAKQIVRKLTMVVLSSEKLDERDKEKDKDDEKVEKPPDNQKLGLLEALLKIGDWQHAQNIMDQMPPYYAASHKLIALAICKLIHITVEPLYRRVGVPKGAKGSPVSALQNKRAPKQVESFEDLRRDVFNMFCYLGPHLSHDPILFAKVVRIGKSFMKEFQSDGSKQEDKEKTEVILSCLLSITDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNGHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTTISSWLQSLASFCGAVFRKYPIDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQEGGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQHKVHKYITSCEMVMAPVHEAVVSLHVAKVWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKSTKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRATGFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVNKICQEEKEKRPDLYALAMGYSGQLKSRKSHMIPENEFHHKDPPPRNAVASVQNGPGGGTSSSSIGSASKSDESGAEETDKSRERSQCGTKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKVKEKEKEKKEKTPATTPEARVLGKESKEKPKEERPNKDDKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPSVESKSTQEREREKEPSRERDVAKEMKSKENVKGGEKPPVSGSLKSPVPRSDISEPDREQKRRKIDTHPSPSHSSTVKVSILYINHNPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDITKRRKEENGTMGVSKHKSESPCESQYPNEKDKEKNKSKSSGKEKGSSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKQYPFYLYISLTVVEGFLIPFMFRIKPFM
Protein: At1g14950/F10B6_18 (Major latex protein type1) (Major latex-like protein) (Polyketide cyclase/dehydrase and lipid transport superfamily protein) (Q39132)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized protein At1g24000
- Uncharacterized protein
- UNC93-like protein 1
- Defensin-like protein 199
- Putative methylesterase 14, chloroplastic
- Tetraspanin-19
- Nuclear-pore anchor
- Small ribosomal subunit protein uS5w
- Protein PLASTID MOVEMENT IMPAIRED 1
- Receptor-like kinase LIP1
Sequence:
MATSGTYVTEVPLKGSAKNHYKRWKSENQLFPDAIGHHIQGVTVHEGDWDSHGAIKSWNYTCDGKQEVFKEKRELDDQKMAVTFRGLDGHVMEQLKVYDVIFQFVPKSQEGCVCKVTMFWEKRYEDSPEPIKYMKFVTSLAADMDDHILKNQSKA
Protein: Antitoxin epsilon (Q57231)
Organism: Streptococcus pyogenes
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate zeta toxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. Continuous synthesis of the epsilon antitoxin is required to counteract the zeta toxin.
Interaction partners:
Sequence:
MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEVNLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA
Protein: Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID50) (TID56) (Q27237)
Organism: Drosophila melanogaster (Fruit fly)
Function: May act as a tumor suppressor in larval imaginal disks.
Subcellular location: Mitochondrion outer membrane.
Interaction partners:
- Heat shock 70 kDa protein cognate 5
- GrpE protein homolog, mitochondrial
- Dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase Alg3
- Hsc70Cb, isoform G
- Mitochondrial import inner membrane translocase subunit TIM14
- Heat shock protein 75 kDa, mitochondrial
Sequence:
MMISCKKLFVFRQLPAVRRCLAAAAFSTPRATSYRILSSAGSGSTRADAPQVRRLHTTRDLLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRREYDTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQSWQFRSSIDPEELFRKIFGEGNFRTNSFDDFADSKFGFGQAQEMVMDLTFAQAARGVNKDVNVNVVDQCPKCAGTKCEPGTKPGRCQYCNGTGFETVSTGPFVMRSTCRYCQGTRQHIKYPCSECEGKGRTVQRRKVTVPVPAGIENGQTVRMQVGSKELFVTFRVERSDYFRREGADVHTDAAISLAQAVLGGTVRVQGVYEDQWINVEPGTSSHHKIMLRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIEAYAELEEDTPGQIHGIANRKDGSKQATAGASEEPGAGAAAKASAAAAGSGASKPGPGAEESEGKDQWTDNKKTKAKEGGGSGSGQGDGGGGGFISKIKSMFN
Protein: Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (mPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) (Q9JI78)
Organism: Mus musculus (Mouse)
Function: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11562482, ECO:0000269|PubMed:12606569, ECO:0000269|PubMed:16055502}.
Interaction partners:
- UV excision repair protein RAD23 homolog B
- E3 ubiquitin-protein ligase AMFR
- Transitional endoplasmic reticulum ATPase
- UBX domain-containing protein 1
- 26S proteasome regulatory subunit 4
- Derlin-1
- UV excision repair protein RAD23 homolog A
- Cytosolic endo-beta-N-acetylglucosaminidase
- Tripartite motif-containing protein 14
Sequence:
MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSSKKVQFSQHPAAAKLPLEQSEDPAGLIRHSGNQTGQLPSLPSAPMVVGDSTILKVLQSNIQHVQLYENPVLQEKALTCIPVSELKRKAQEKLFRARKLDKGTNVSDEDFLLLELLHWFKEEFFRWVNNIVCSKCGGETRSRDEALLPNDDELKWGAKNVENHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHDEVMSRRTKVKEELLRETINGLNKQRQLSLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETGLERKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNNINISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDTVSIRTSSQSFESGSVRWKLRSETAQVNLLGDKNLRSYNDFSGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDSGENGLEIIITFNDL
Protein: CST complex subunit STN1 (Suppressor of cdc thirteen homolog) (AtSTN1) (Q9LMK5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Associates with enzymatically active telomerase. Plays a genomewide role in DNA replication and facilitates re-replication at non-telomeric loci.
Subcellular location: Nucleus {ECO:0000269|PubMed:19064932}. Chromosome, telomere {ECO:0000269|PubMed:19064932}.
Interaction partners:
- CST complex subunit TEN1
- CST complex subunit CTC1
- Protection of telomeres protein 1a
- Telomerase reverse transcriptase
- Protection of telomeres protein 1b
- Protection of telomeres protein 1c
- Thylakoidal processing peptidase 1, chloroplastic
- Telomere repeat-binding protein 1
- ATP-dependent DNA helicase 2 subunit KU70
- DNA polymerase alpha catalytic subunit
Sequence:
MDRSLQSTHAKLVARDIQRLTQSPTESNSFSLLGGACVSRVEIVGTIVSRDLTPKFLKFGVDDGTGCVTCVMWLNQLTSSYFSRWDPATILLLASAARKQAAQIRIGAVARVRGRVGSYRGVMQITANVAVAERDPNAEILHWLECLKLGQSCYRVRIQS