wanglab/gogpt-training-data huggingface dataset:
Protein: Receptor-like protein 41 (AtRLP41) (Q9LJS2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in ABA-induced senescence responses.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- RPW8-like protein 3
Sequence:
MSELLLRLNFLLLLLLSCVSPSSFVTFNNPVVGLGACGPHQIQAFTQFKNEFNTRACNHSSPWNGVWCDNSTGAVTKIQFMACLSGTLKSNSSLFQFHELRSLLLIHNNFTSSSISSKFGMLNKLEVLFLSSSGFLGQVPFSFSNLSMLSALDLSDNELTGSLSFVRNLRKLRVLDVSYNHFSGILNPNSSLFELHHLTYLSLGSNSFTSSTLPYEFGNLNKLELLDVSSNSFFGQVPPTISNLTQLTELYLPLNDFTGSLPLVQNLTKLSILALFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGSIEVPNSSSSSRLESLYLGKNHFEGKILKPISKLINLKELDLSFLSTSYPIDLSLFSSFKSLLVLDLTGDWISQAGLSSDSYISLTLEALYMKQCNISDFPNILKSLPNLECIDVSNNRVSGKIPEWLWSLPRLSSVFIGDNLLTGFEGSSEILVNSSVQILVLDSNSLEGALPHLPLSIIYFSARYNRFKGDIPLSICNRSSLDVLDLRYNNFTGPIPPCLSNLLFLNLRKNNLEGSIPDTYFADAPLRSLDVGYNRLTGKLPRSLLNCSALQFLSVDHNGIEDTFPFYLKVLPKLQVLLLSSNKFYGPLSPPNQGSLGFPELRILEIAGNKLTGSLPQDFFVNWKASSLTMNEDQGLYMVYSKVVYGIYYLSYLATIDLQYKGLSMEQKWVLTSSATIDLSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPLSLANLVKIESLDLSSNQLSGTIPNGLGTLSFLAYVNVSHNQLNGEIPQGTQITGQPKSSFEGNAGLCGLPLQQRCFGTNAPPAHQFKEEEDEEQEQVLNWEGVAIGYGVGVLLGLAIAQLIASYKPEWLACLIKSRNR
Protein: Protein WALLS ARE THIN 1 (Q94AP3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for secondary wall formation in fibers, especially in short days conditions. Promotes indole metabolism and transport (e.g. tryptophan, neoglucobrassicin and auxin (indole-3-acetic acid)). May prevent salicylic-acid (SA) accumulation.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:17151019, ECO:0000269|PubMed:20497379}; Multi-pass membrane protein {ECO:0000269|PubMed:17151019, ECO:0000269|PubMed:20497379}. Note=Also detected in transvacuolar strands.
Interaction partners:
- Auxin efflux carrier component 8
- Auxin efflux carrier component 5
- Auxin transporter protein 1
- Nodulin/glutamine synthase-like protein
- Protein PIN-LIKES 2
Sequence:
MADNTDNRRSLWGVPEKLQLHIAMLTLQFGYAGFHVVSRAALNMGISKLVFPVYRNIIALLLLLPFAYFLEKKERPAITLNFLIQFFFLALIGITANQGFYLLGLDNTSPTFASSMQNSVPAITFLMAALLRIEKVRINRRDGISKILGTALCVAGASVITLYKGPTIYTPASHLHAHLLTTNSAVLAPLGNAAPKNWTLGCIYLIGHCLSWSGWLVFQAPVLKSYPARLSVTSYTCFFGIIQFLIIAAFCERDSQAWVFHSGWELFTILYAGIVASGIAFAVQIWCIDRGGPVFVAVYQPVQTLVVAIMASIALGEEFYLGGIIGAVLIIAGLYFVLYGKSEERKFAALEKAAIQSSAEHGIERAPVSRNSIKSSITTPLLHQSTDNV
Protein: Fatty acid-binding protein, intestinal (Fatty acid-binding protein 2) (Intestinal-type fatty acid-binding protein) (I-FABP) (P02693)
Organism: Rattus norvegicus (Rat)
Function: FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity).
Subcellular location: Cytoplasm.
Interaction partners:
- Fatty acid-binding protein, liver
- Aspartate aminotransferase, mitochondrial
- Gastrotropin
- Platelet glycoprotein 4
- Long-chain fatty acid transport protein 1
- Diacylglycerol O-acyltransferase 1
- Peroxisome proliferator-activated receptor gamma
- Fatty acid-binding protein 5
- Apolipoprotein B-100
- Peroxisome proliferator-activated receptor alpha
Sequence:
MAFDGTWKVDRNENYEKFMEKMGINVVKRKLGAHDNLKLTITQEGNKFTVKESSNFRNIDVVFELGVDFAYSLADGTELTGTWTMEGNKLVGKFKRVDNGKELIAVREISGNELIQTYTYEGVEAKRIFKKE
Protein: serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (Q384V4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Acyl carrier protein
- isoleucine--tRNA ligase
- methionine--tRNA ligase
- glycine--tRNA ligase
- Valine--tRNA ligase, mitochondrial
- arginine--tRNA ligase
- Tyrosyl/methionyl-tRNA synthetase, putative
- proline--tRNA ligase
- tyrosine--tRNA ligase
- tRNA
Sequence:
MVLDIQLFRDETGANIIRESQRRRFADPDIVDAIIEADKKWRRTQFLTEASKKLINICSKAVGAKKKAKEADGDTSEIPPQVKEAYENGTLKGEQVEQLCVLQLKQLSKDLSDQVAGLAKEAQQLEEERDKLMLNVGNILHESVPIAQDEETGNTVVRTFGNTTKRAKLNHVSIMERLGMMDTSKAVTSMAGGRSYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVMGEVAQLSQFDEELYQVSGDGDKKYLIATSEMPIAAYHRGRWFTELKEPLKYAGMSTCFRKEAGAHGRDTLGIFRVHQFDKIEQFVVCSPRQEESWRHLEDMITTSEEFNKSLGLPYRVVNICSGALNNAAAKKYDLEAWFPASGAFRELVSCSNCTDYQSQSVNCRYGPNLRGTAAQNVKEYCHMLNGTLCAITRTMCCICENYQTEEGVVIPDVLRPYMMGIEMIRFENNAQAEGTTPDKGE
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (A0A8I6GBZ8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLTYYEGRAEKKYRKGFIDISKIKCVEIVKNDDGIIPCQNKFPFQVVHDANTLYIFAPSPQSRDRWVKKLKEEIKNNNNIMIKYHPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKRRPPPPIPPEEENTEEIVVAMYDFQATEAHDLRLERGQEYIILEKNDTHWWRARDKYGSEGYIPSNYVTGKKSNNLDQYEDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLPRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVECEETFGR
Protein: HTH-type transcriptional regulator TreR (Trehalose operon repressor) (P36673)
Organism: Escherichia coli (strain K12)
Function: Repressor of the treBC operon. It is able to bind trehalose-6-phosphate and trehalose.
Interaction partners:
- PTS system trehalose-specific EIIBC component
- Trehalose-6-phosphate hydrolase
Sequence:
MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQLTRERVEAVMNQHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQFSPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDEGAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAMKQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPEIVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS
Protein: Glutathione S-transferase A3 (EC 2.5.1.18) (GST class-alpha member 3) (Glutathione S-transferase A3-3) (Q16772)
Organism: Homo sapiens (Human)
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. Has substantial activity toward aflatoxin B1-8,9-epoxide (By similarity).
Subcellular location: Cytoplasm.
Interaction partners:
- Glutathione S-transferase A1
- Glutathione S-transferase A2
- Epoxide hydrolase 1
- Glutathione reductase, mitochondrial
- Cytochrome P450 1A1
- Cytochrome P450 1A2
- Cytochrome P450 2E1
- Peroxiredoxin-6
- Phospholipid hydroperoxide glutathione peroxidase GPX4
- Cytochrome P450 3A4)
Sequence:
MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
Protein: Keratin-associated protein 10-10 (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10) (P60014)
Organism: Homo sapiens (Human)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Interaction partners:
- Keratin-associated protein 10-11
- Keratin-associated protein 10-7
- Keratin-associated protein 10-9
- Keratin-associated protein 10-1
- Keratin-associated protein 10-3
Sequence:
MAASTMSICSSACTDSWRVVDCPESCCEPCCCAPAPSLTLVCTPVSCVSSPCCQTACEPSACQSGYTSSCTTPCYQQSSCQPDCCTSSPCQQACCVPVCCVPVCCVPVCNKPVCFVPTCSESSPSCCQQSSCQPTCCTSSPCQQACCVPVCSKSVCYVPVCSGASTSCCQQSSCQPACCTASCCRPSSSVSLLCHPVCKSTCCVPVPSCGASASSCQPSCCRTASCVSLLCRPVCSRPACYSLCSGQKSSC
Protein: THAP domain-containing protein 7 (Q9BT49)
Organism: Homo sapiens (Human)
Function: Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- THAP domain-containing protein 11
- 52 kDa repressor of the inhibitor of the protein kinase
- THAP domain-containing protein 1
- Histone H4
- TATA box-binding protein-associated factor RNA polymerase I subunit B
- Nuclear receptor corepressor 1
- Histone H4-like protein type G
- Protein SET
Sequence:
MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEYIYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDFAMQLSSSMA
Protein: Pelophylaxin-1 (Q2WCN8)
Organism: Pelophylax fukienensis (Fukien gold-striped pond frog) (Rana fukienensis)
Function: Antimicrobial peptide.
Subcellular location: Secreted {ECO:0000255, ECO:0000269|PubMed:16139927}.
Interaction partners:
Sequence:
MFTMKKSLLLVFFLGTIALSLCEEERGADDDNGGEITDEEIKRGILTDTLKGAAKNVAGVLLDKLKCKITGGC
Protein: Proton-coupled amino acid transporter-like protein pathetic (Q9VT04)
Organism: Drosophila melanogaster (Fruit fly)
Function: Amino acid transporter which has pH-dependent electrogenic transport activity for alanine and glycine but not for proline. Plays a role in positive regulation of growth by directly or indirectly modulating the effects of the TOR signaling pathway. Required in a cell-autonomous manner for dendrite growth in neurons with large dendrite arbors.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22574197, ECO:0000269|PubMed:26063572}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:22574197}; Multi-pass membrane protein {ECO:0000255}. Late endosome membrane {ECO:0000269|PubMed:22574197}; Multi-pass membrane protein {ECO:0000255}. Cell projection, axon {ECO:0000269|PubMed:26063572}. Cell projection, dendrite {ECO:0000269|PubMed:26063572}. Perikaryon {ECO:0000269|PubMed:26063572}. Cytoplasm {ECO:0000269|PubMed:22574197}. Note=Localizes to endolysosomes in class IV da neurons. {ECO:0000269|PubMed:26063572}.
Interaction partners:
Sequence:
MVNIVDSGSKHAPQEMEQFLPGEGKVMYKIQPRKSDTEQALAGNDFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTRRTKMTFAEIAEAAFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGTAVSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQDLPPVEERESVVWSTLPQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPTLVNYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWESGFGKYNWILWKNAIITLCGIGALVFGTQAAIKDIVKAYSNNENVGE
Protein: Pre-mRNA-splicing factor SPF27 homolog (Modifier of SNC1 member 4) (Protein BCAS2 homolog) (Q949S9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Involved in mRNA splicing.
Subcellular location: Nucleus {ECO:0000269|PubMed:17575050, ECO:0000269|PubMed:29588169}.
Interaction partners:
- Protein pleiotropic regulatory locus 1
- Cwf15 / Cwc15 cell cycle control family protein
- Pre-mRNA-processing factor 19 homolog 2
- Cell division cycle 5-like protein
- Protein pleiotropic regulator PRL2
- Pre-mRNA-processing-splicing factor 8A
- Pre-mRNA-processing factor 19 homolog 1
- DExH-box ATP-dependent RNA helicase DExH12
- Zinc finger CCCH domain-containing protein 4
- Tetratricopeptide repeat
Sequence:
MATNNGDVLMLEATPEAARPWASAANAEVIDALPYIDDDYGNPLIKSEVDRLVEEEMRRSSKKPADFLKDLPPLPKFDFKNCPVLGKEYERVRAGKPPVRIDFESRYKLEMPPANKRNDDAAWKQYLQKNQRSLQQKLIELENLELMSKLGPELWRQNNHRLEVFLTRMQRLAQEQNEEIEKVNRERKYHQQTTSYELNALSQEWRQLCVKNMEIQSACAMLETQIDSFKKEAAERGWNLEEKLENVEPLQMQ
Protein: Perilipin 6 (Zgc:162150 protein) (A4IG34)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Lipid droplet {ECO:0000256|ARBA:ARBA00004502}.
Interaction partners:
- BSCL2 lipid droplet biogenesis-associated, seipin.
- Scavenger receptor class B member 1
- SEC14-like lipid-binding 8
- Tetratricopeptide repeat domain 39B.
Sequence:
MIKTRNSEGNVLNRVVKLPLVSSALQQASSVYTVVKGRYPLLGFVGGVAELSVRSASTAALQQAAPLLQNLQPEIEAVNTYAMVGLDQLEKYFPILQQPTDEVVANLKDAFFSRLDDAQSRLNDELDRAVDRWDRLIDQMWRLLAEAQGSGPGRAITAGLDELITQSEEAVAYYLPLPPTLRYEYERMVQSYEDEHLHNDDDEDDDEEEPPMWMRIRSLLLCLYFQLYYRLMKLRERVDNILQMLGAAAETVGLKRLMEMVEMLLQLLLSFYTARVHHVEELRSQLVSRLTAGLQALTVWPPVQQMLVLPTQVRALTNDLLELGQILIQLLINTTPLYDLVKQVSDLDAANNPTPDEVPESPSGRASANSLFLKAMDGRPRRRRSLYARSRRGSSSGVPTSPVQSPTPTPSPVPANGRKGSLKTDSNSVGPPELDTLAVPTTDMIRRRSSTTEVLLAPIMQLVTQSQRAFEYLSSSNEDQVLPVVETTEH
Protein: Potassium channel tetramerization domain containing 1 (A0A2U3U043)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MARMPGSGDCNTSAGGSASAAAAAAENNGERGEGERGAGGRGRRHSRPHYCSAGEEEEEEEEEDEIQEVQITGDEEEEEDGGGGLEEDEEEEEEEEMGLDWDEPLEPEDSAGEELEPEPVHMINMDQSAALEPEAPPRLLAPRARGGPPGDGSELDPDVLQRPERARLSENTRLATRYAVRIFREYLSEKAQSPDFETMDKGALCRVLRSFYAEARSKSGQLYSKSSLISIRSSLNRYLNEPPYCRTLDLTKDPELRSANLTLAAVIRKLEEQGAGPVVQKQAITRADLRKLYTSSVFSTNTPFGLLNKVWFETCMYFCTRGRENQRELEEDSFGLAMDEDGRKFVYFKSLGPYHKSRSSSWSKKRAESSDEENLPRMYETGTEFCPYASFVKYLSKRNPLCKAFFQRPRDHCSEGDVTWYENKAIGKNLLGTRMQMLSKAAKLSKTYTNHCIGAVSIATLNSIAGIGTKLGSPAPQGCYAEALNGAARHHSHHPPTHPSHHHRPQPPSLGNTYILPKDSQVGPDVKSEAAPKRALYESVFGSGEICGPTSPKRLCIRPSEPVDAVVVVSVKHDPLPLLPEANGHRSTNSPTIVSPAIVSPTQDSRPNMSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELRRTPRVPSVIRIKQEPLD
Protein: Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2) (Q8BSS9)
Organism: Mus musculus (Mouse)
Function: Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O75334}. Cell surface {ECO:0000250|UniProtKB:O75334}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:O75334}. Note=Colocalizes with PTPRF at the cell surface. {ECO:0000250|UniProtKB:O75334}.
Interaction partners:
- Peripheral plasma membrane protein CASK
- Rho GTPase-activating protein SYDE1
- ARF GTPase-activating protein GIT1
- Regulating synaptic membrane exocytosis protein 1
- Regulating synaptic membrane exocytosis protein 2
- Protein lin-7 homolog A
- Amyloid-beta A4 precursor protein-binding family A member 1
- Receptor-type tyrosine-protein phosphatase S
- Protein unc-13 homolog B
- Liprin-beta-1
Sequence:
MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEAGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLTALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESENFRKNLEESLHDKVSLAEEIEKLRSELDQMKMRTGSLIEPTISRTHIDTSTELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAVRMTHTLPSSYHNDARSSLSASLEPDSLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLTAPAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC
Protein: Kelch-like protein 23 (Q8NBE8)
Organism: Homo sapiens (Human)
Interaction partners:
- Cullin-3
Sequence:
MALKGQEDYIYLFKDSTHPVDFLDAFRTFYLDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKNKIKLSGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACERFLVRHLDIDNCIGMHSFAEFHVCPELEKESRRILCSKFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAIIEPVIKWTAHDVENRIECLYNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIEALDTVWIYNSESDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWIPIANMIKGVGNATACVLHDVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITSSPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWREIAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV
Protein: Ecdysone-inducible gene E1, isoform A (Ecdysone-inducible gene E1, isoform C) (Q7KUB3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTATARQSATSRKQPAIAMLNGNAFTVKRLLALLIIFTVVDASRSLELGDKCQHDMDCTDFIKGSSCSALGYCECAPYFVQLDSKRCLSSQLLGGDCQLSEQCSMKVANSSCLEGACRCVEGFLQFRKHTCLGPAHPGAVCYSHAHCQMFDTRTHCDFLIPNLFGRCQCTSPAKMVGGLCVAPAADQEDQKQEQAVEKVEQPASSTTTTTTTTTTPRPTTRTTSRTTTTTTAAPPTTTRRTTTTTTTTTPAPILLEDELPASVEEQSLEEDDGETTKLRPEVVEVDNGEKLEAVDLAHEETELTQQQNQLDEQQHQEEEQKHQEEEQHRIEQQQNQEEEQQQQQHQQQVIDQASDAELPQSSQDATTGVQQLLTPADVPTEDAINAEQETEAGPTEDYPYKIDEEYTEEHNDKPEAPELTVDQPEHEESPVATEIVPIEADEEAAEASGGQEIASSPIDDTMKFDYETSVDDVEPAKPEDEKETEAVHQATNEGVVPIDTESETDAETSTEPQIQTQLLQEDGEPETSQTVADEELIPVNEGETESVTKAADETEEIPEEETPEDLASGDHELDVAAASHDDEVETPKQEEPTEALKIEQPAQVESESQNVDEVGKPEEPQAEMEIEKEKEETAATEAAEVELPATEAKPDMESEIDQVEQSADIKPTSGEDDLNEANQLNQDQVTEPAALEQEEIEEKEPEQVVDMHEDADEATTEKPVQDHDQEEVEAITEAEHGQLTYPTNDDELAPVEIEPELTTEEPEIAENTTELPEQQQQQQDEEEIEEAALAHEEQVQQVEPEENANAIKTPEVSEAIAEPQADLETPSATEKEIEPQTADHVEEEPVAITERIQEAEPEPEIEPTNDEVSQVDADQAEPELPIKSDADIAEEAAEEPAQTEVAPEVETETEASESAQTSPEISVEQDEVAIDKNENDNIIQGAEPNEEDELIPEPQPMPEEEELPVQQEASAVPEDHKLTKPEMDYTSVEHLQELSRPEETTAAIEAEESDSRESTLAPEAPDAPIAIVSEERDPEHDPQNFHESESIADILSDLMLEADSTVPPVPFGQQPAQTVPMVEANSENEEEQAHEAISDLQAEADETQEHAEQVQPVNEPGTAIPELFAEAAKDEEDVPALPESDESKTEQPSALEVEQHIASEAEQTPVEDEHQYDEEEHQQDQEEHQQDEDEPLKEVETESLPEEATTEKFQEPEPEEVNTPLPEELPFDLTDHSDVNRFNELQSESLILESTTNIDGLQELDNNHIEEEEPAAHAIPHEEATPNPADIVEITTQTMLGLASRVTLMEPAAPVVTTLMPLMTADEPTPEPVSPAAIPSASLAAIKPGTELRKRVDLGLEAVSLGLACSSDRQCQLADPHTVCNRRGVCDCAAGEEGSQCSAERTGCSPGTFQCRSSGVCISWFFVCDGRADCNDASDEECTHNARLNQTCPTESFRCQRSGRCISRAALCDGRRQCPHGEDELGCDGSVKGGNACPEHTFRCGSGECLPEYEYCNAIVSCKDGSDEPPHLCGSRALPNLFMRLIEAGGLLGGGRREADAYCPHRCSNGLCRSTAIVCSGRDGCGDGTDEQTCSVCRCPAPTAASLPAFLARQRPMPLW
Protein: PDZ/DHR/GLGF domain protein (A0L9W2)
Organism: Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Probable membrane transporter protein
- Peptidase S1 and S6, chymotrypsin/Hap
- Probable periplasmic serine endoprotease DegP-like
- PDZ/DHR/GLGF domain protein
- Cation diffusion facilitator family transporter
- Tetratricopeptide TPR_2 repeat protein
Sequence:
MKIRGTTIVALGMLVVAITVLASMIDLPGSDMSVTPPPVETPVGAPIAGNTGDPAMGIAVAMRRGVVEQRAPIPALSSANGSFVAPNVQFSEAHWQGMEALPLTIELKRKLKLPLDLEGLLIDETTLNAAVSGLLAGDVLIAINGRKVKSLKQMQDETRRSQMDRRASLAVYRKGRLLTLTLVDEANLGLAQVETAPMILPGDIMPHPYRGPCTQCHAIGTAGLMMPDPDLIVLPPGPIRAGATMPHRDRGPCGACHAIIQ
Protein: Tissue-type plasminogen activator (t-PA) (t-plasminogen activator) (tPA) (EC 3.4.21.68) [Cleaved into: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B] (P19637)
Organism: Rattus norvegicus (Rat)
Function: Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy.
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Plasminogen activator inhibitor 1
- Annexin A2
- Plasminogen
- Plasminogen activator inhibitor 2 type A
- Protein S100-A10
- Glia-derived nexin
- Aa1018
- Urokinase plasminogen activator surface receptor
- Serpin family F member 2
- von Willebrand factor
Sequence:
MKGELLCVLLLCGVAFTLPDQGIHRRFRRGARSYRATCRDEQTQTTYQQHQSWLRPMLRGNRVEYCRCNSGLAQCHSVPVRSCSEPRCFNGGTCQQALYFSDFVCQCPDGFVGKRCDIDTRATCFEGQGITYRGTWSTAENGAECINWNSSALSQKPYSARRPNAIKLGLGNHNYCRNPDRDVKPWCYVFKAGKYTTEFCSTPACPKGPTEDCYVGKGVTYRGTHSFTTSKASCLPWNSMILIGKTYTAWRANSQALGLGRHNYCRNPDGDAKPWCHVMKDRKLTWEYCDMSPCSTCGLRQYKQPQFRIKGGLFTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCFVERFPPHHLKVVLGRTYRVVPGEEEQTFEIEKYIVHKEFDDDTYDNDIALLQLRSDSSQCAQESSSVGTACLPDPDVQLPDWTECELSGYGKHEASSPFFSDRLKEAHVRLYPSSRCTSQHLFNKTITSNMLCAGDTRTGGNQDVHDACQGDSGGPLVCMIDKRMTLLGIISWGLGCGQKDVPGIYTKVTNYLNWIQDNMKQ
Protein: protein kinase C (EC 2.7.11.13) (A0A0R4IJZ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}. Midbody {ECO:0000256|ARBA:ARBA00004214}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAADPMQAGMVSEQLGLGHNLDLSDTMVQQKLDEIKEQIKREIRKELKIKEGVENLRKVTTEKKRLAYVDNMLKKSNKKLEELHQELQELNAHIVVKDPEDLLLECPLTLDSPKSESRTCTSSSRLAALKKQNDIELKVKQGAENMIQMYSNGSSKDRKLLATAQQMLQDSKTKIEFIRMQILKASQTSELSFDNNDVIAKPIISPLDLRVEELCHHTRIEFAVAEGAKNVMKLLGSGKLAEKRAHSEAQARFNESSQKLDLLKYSLEQRLNELPKNHPKCSLIMEELSLMSSPALSPRQSFISTQNHNSTVKNQYSTKPAALTGKLEVRLMGCQDLLESVPGRSKATSVPLPGWSPSETRSSFMSRGNRRGTSVRNLSKNDDLSNEISAVLKLDNTVVGQTSWKPVSNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRTKLQRQKKIFSKQQGRTFLRAPQMSIGTWGRLVRRAIPSPNNSFSPLAAETGHSSHPGTPALRSDPIVTKLDFDRDTTPKNYSPVSVREVLPEDKISNKERERGALTAFAYRNDRNSIIVQSGLEEIVEHDTPPSALQLINVQKSTEIRDEEEQFHFSLKDFKCVAVLGRGHFGKVLLAEYTITGEMFAIKALKKGDIVARDEVESLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHADVFSEPRATFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRVLSTEAISIMRRLLRRNPERRLGAAERDAEDVKKHLFFRDIDWDGLLAKKVKPPFVPTIQCSSDVSNFDDEFTSEAPVLTPPREPRPLNQHEQDLFTDFDYIADWC
Protein: Low density lipoprotein receptor (Low density lipoprotein receptor a precursor) (Q7ZZT0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Proprotein convertase subtilisin/kexin type 9
- Low density lipoprotein receptor adaptor protein 1b.
- Low density lipoprotein receptor adaptor protein 1a.
- Si:ch211-204c21.1.
- Low density lipoprotein receptor adapter protein 1 isoform X1
- Apolipoprotein Ba.
- Transmembrane serine protease 5
Sequence:
MEISFMLLLAVTLFCPVQSGALTCDSRQYQCGNGKCITARWVCDETDDCGDGTDELPAACLAKTCRPSQFSCGGRLNQCIPKSWKCDGKADCENNADEEGCDPRQCHDGEFRCGSGQCVTAAFVCDDEIDCEDGSDEVSCPPTTCGSSSFRCNNAQCVPRLWVCDGDADCADNSDELPEKCGPGTSKPTKNPCTSMEFHCGSGECIHGSWKCDGGADCLDHSDEQNCSLPTCRPDEFQCGDGSCIHGSRQCNHVYDCKDMSDELGCVNATHCEPPYRFKCRSGECISMEKVCNKQRDCRDWSDEPLRECDSNECLYNNGGCSHICNDLKIGYECLCPTGFRLVDKRRCEDIDECANPDTCSQICVNQMGSYKCECEDGYQMDPASKACKAIGTIAYLFFTNRHEVRKMTLDRSEYIRVIPRLKNVVALDMNIASRDIYWSDLSLKKIYSIRGAISVATADGSRRKTLFKENLAKPRAIVVDPIKNFMFWTDWGTPAKIEKSGLNGVDRSTLVADDIVWPNGITLDLLTERLYWVDSKLHTLSSISVQGDGRRTLIIDQGKLAHPLSLTVFEEKVFWTDVSNNAILSANRVTGGDITKVAEHLSSPEDIVLFHNLKQPTGINWCRINNGGCEFLCLAAPQINRFSPKYTCACPDNMMLARDMRKCVPAVVTAATPVRPEIPTTIRPQVPSETTPKPARPSTTNSQPLPTPAPKIPNRPTQAATLVPSQATTKLPFFTQTDVHFGDVKAVSDTSSSTLWALYIVVPLVPFIIHSGMNHQLIQHVFRQRMPFQPQPISRKHPHTLIHTDTDNLAYPIHLYRLTVGETGAPGGSPHEHRENIQTPHRNTSCGLNQRPSCSLLCLVVGGAALFWRKWRQKNTNSIHFDNPVYQKTTEDQVHLCRNNSSDGYFYPQV