Protein: BEACH domain-containing protein lvsA (Large volume sphere mutant protein A) (Q55DM1)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in myosin-independent cytokinesis and early steps of phagocytosis. Also involved in contractile vacuole-mediated osmoregulation.
Subcellular location: Contractile vacuole membrane {ECO:0000269|PubMed:11872142, ECO:0000269|PubMed:15086784}; Peripheral membrane protein {ECO:0000269|PubMed:11872142, ECO:0000269|PubMed:15086784}.
Interaction partners:
- Drainin
- Autophagy protein 5
- DNA helicase
- FK506-binding protein 1
Sequence:
MFRRFKDLIGTSEDPTPQVPHSPGHPPHQPPQQQQQQQQQQQQQQQQQQQQQQQQQQPQPQQPLSPRSVSSPIGSTTSSNSTSSFSSPVRKYSSATEESSSINSNNNNNNNKNNNNNNNSNIIESNINVWTIMIGSEVEVIRSQATAQKLKLLWQEFLSSKSDKDKVMRLNKLLPYFIGLYEDKKIDTKSPMVDIFGNNSKSFSFAISRRLVKDINEIMKQANSPQQPPQPPQLIKETIAKEIYKFFSTTSGQVSGFELLYSIEILSESNTSCAEAMAEASIPSMLVRCLQYFFLVPYTTMMETTKGIIEEKLIRTLCFLSKQKSAIEELQKTDTLSTLFALMSNECPPSHRPLRAKIGSFGLELTDLYPPTITYINSKRVIANIIKDLTNYYMFTPESYVTLCRIIIKILSESSKKSTILLDEFQRNDGYTFLVDSLFRLESSKDKPALFEQLLDSICSLVYIGYGNVSLPVENSSVPYQTSINNIKEISNQNYISKNGNAFKVLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYESLSNGLKYHVMKIVCFVVTVLNCVPFQELSTFSLLVGENPSFYTLEMINQLITTLVNFEFRYKHIFRETGLLDILVKVIDVIAQDIIRLNNSKKIDDDDENNNNNNNNNNNNNNNNNNNNDNDNNNNNDNNNEENGSGSNGPIVPCMTGNGEKEADSNDQALNSIIKVESFQILLDSLFILISENPDNISLIRSFSIFNILLRFLPYSSVRGKSLRILQQLIKYDPEPTQKEFDGLIKVLTSVNKENYPMKSDILNATRKLFNISKHARDSFREHGGFVSIISVFISLESSFSPNRKDSRNWDMEKLELIESICRCTTSALCGNVINRENFEQQIGYKTFSSCLIMTGVLGTEFSKSVVDFIFDMVTENLNASDQISNQMIINNVESFNVILDIIPHIENKDFRLQIISRINKMAEYGRYNQEALSKLSIPDWILSRFPSNLSNANDPLQPLLLSLIQTVGANCLSGSELRQFVKLLQPEHSPEVLLKILSSMAKSPPTPPYFEFNLSKIPFGYIRVPITERAWPPTNGYTIMFWLYIDKFPTVNNNNNNNNSSNNSNNSNNSNNNNNNNNNNDQIDLVHIYSDDKKSSLYIYLKNGIITVNIINSSKYVIEIPSYKFVEGKWYHIGIVHARRLLGGTDFKLFVDGFLKYTATKAQYPAQITSGSMLICDIGVSNQNRFPTDSIWRIGTFYLLEDSLGAKHINTIYFLGPNYASNFKGRFSPYQTYEIVNSANLMAIKDLDYGDQLGPLNLAKVSMQIDENKILVGLCASNKLIRTNNSSKVVYNEIFNGIINELSQNHGVALNVFSSPNGTSPNLTGLQNNNNNNNNSGGSNSKKDLEGRVEIINQADLTTKLRGVLIGSVEAFRRNKVADSIKKIGGMPISLLLLEKANSEETLFDSLGLLVGLIQYHPTNTHEMSQINGYELLAWVLKKKASLGLFNSNILELLFDLIGINGNCSTTITSRAPQEGTVANWNACKYIMMNWDIWRLTTPALQRHVINGYNSLIVNNIQRRFNIDSLRKVNVIQEIFDILSSSTNEEPLPESVASSVINVLYNILSYGGLIEDDIRQISAFLISHLHKDIPTPSSSSSSSSTSSTSSRRKSIHRSKLATMELSNTATIQLVNHVFYTFLKVVSNCQTQETAAIFRRVSSYWCFFFIDENLPPLTVSLALRVTCIFFLYKYDYCSTFIKKSGFKLLEKVLPSLSGHQEIYLCLLHLLLGGDPKLLVDLDLSSSSGGAGGTTIVFHELLRIFTPFEKSLYCIEAAQLILSLIKRSYEDNYQYLEQKQQELQNANQGLDNDELLSSLISNVNINNSINNNDNSNSPLSTFQTISRSVSSSSISSNISSSSSSSTLVNSSNSNNNNNTPTSGLASTITKFGNLWNKFEEKTLEFAVTTGAIDENSTGATDAQQAALKKKNRMSIQSSPFQSKNLGTGGDDSVTNTPNGSSLHNRVTGMDDDSKLNGALGGGGGGGGGGVSVGDNQPINFNLYDEMLPELKISQFATPEESSNLQYTMLTYFIYLFHENQYFQQECYSQPMVEELISILFPNGKINLPPLYNSTGQTNGIKDRVLDLVVKFLCQIMLSAMRKTSKAISIIEMVLEGAPTTATDEEFILYHSRILLDLMYVVETNITKTEFFDNERVHSNLIKLSSMLVDRVNLDQLVKNNKIIIAKRIFLFIVKILEKLEADRVGLQKTVQSLYKSLNRIILYLINHTTDTDLSFVANHIINHQRIIFSENNLDSDFMNAFCYPLYKLVISDQHEHVDNSIKLWRLLLSLKTSSYIESLATVLQLKVSSGSNQRQSEIIDLKPGFELLRNTSGNGAFNNDEFKLWINDNIQTITQVFEENPKKQHLSFKNNEKKHSSEHTLPSLKSRRTERLSKKQRQDRKDQSHQEEKSKHITKKAQYFVRSESDRRKKIKQLESDKQKFNAIQWENMRAQITRERAVWGPSEPHPLDKWKLDSTEGPYRMRKKMEKNYNFYKNYPYVPPSFDEQNNSLLPIPCSADSETYMNIVGTEEANLLESSYWKFDLLSTNQVITSSTNTSSITNNNNNNNNNNNNNNNNNNNTITKSTSQNANNNNNANNMNQSTSSSSSNTTTTTTPQQSSSQIKVSSPELSSNEITPPTSPVQSSSEDVFKSPKLQSSTVEGQLSRNPSSSELFNDNSSTISEENSSLTSASTTLSPPPPSTQTTTTTTTSTPTTQSSVATTTTGNTNEVDEETSTNNQTTSEDETQAFIRLLDPYDQSYLKDAMRKDPRLNGIMYNCGSVDGMDKIEGILIFCPVYMYIFDGYYKDENTGDISEVEEKINSEWLPEGTVLPMKKKIIHYFLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLVNNVSSHNTIGGDAQGITGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKFRERFENWDDQEPNEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWASSSQGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAATIAQINNFGQTPKQLFDKPHPKRNATLMGLPFYAKALTGNFIKDIGEPVGQIRLINDRATCVGFNKVLLPPNHSKYMLWGLPDGSIRYNTGDKIKVLEDHHDGPLTCLTATEDGRICVSGGSDSLICVYNLKRFSLAKRLSGHTGSITCVSASRPYSIIVSGSDDRTCIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISVYTVNGELLINYKTSQIANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLETRLLPDNNNSNNNNNNNNNNNNNATQIPSTNNNKLKFKNVIILRATFSNSQSHSTAITSIFLTNDQQKFYTGDITGRVCMWSDNEASQVKQRGWINTDIRGILQSEKK