wanglab/gogpt-training-data huggingface dataset:
Protein: Multiprotein-bridging factor 1 (Suppressor of frameshift mutations protein 13) (O14467)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein eS30A
- Small ribosomal subunit protein uS4A
- Small ribosomal subunit protein eS10A
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein eS21B
- Small ribosomal subunit protein uS7
Sequence:
MSDWDTNTIIGSRARAGGSGPRANVARSQGQINAARRQGLVVSVDKKYGSTNTRGDNEGQRLTKVDRETDIVKPKKLDPNVGRAISRARTDKKMSQKDLATKINEKPTVVNDYEAARAIPNQQVLSKLERALGVKLRGNNIGSPLGAPKKK
Protein: Probable histone H2A.2 (HTA13) (Q9LHQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
Interaction partners:
- Histone H4
- Histone H2B.4
- Histone H2B.1
- Lysine-specific demethylase ELF6
- C2H2-type zinc finger family protein
- Histone H2B.10
- Histone H2B.8
- Zinc ion binding / DNA binding protein
- PHD finger family protein / SWIB complex BAF60b domain-containing protein / GYF domain-containing protein
- Defensin-like protein 11
Sequence:
MAGRGKTLGSGVAKKSTSRSSKAGLQFPVGRIARFLKNGKYATRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIVPRHIQLAVRNDEELSKLLGDVTIANGGVMPNIHSLLLPKKAGASKPSADED
Protein: Mesoderm induction early response protein 3 (Mi-er3) (Q7Z3K6)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624}.
Interaction partners:
- Histone deacetylase 2
- Histone deacetylase 1
- Bromo adjacent homology domain-containing 1 protein
- UPF0547 protein C16orf87
Sequence:
MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEEMMDEGKNFSSEIEDLEKEGTMPLEDLLAFYGYEPTIPAVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSDFFPRPLRSNTACDGDKESEVEDVETDSGNSPEDLRKEIMIGLQYQAEIPPYLGEYDGNEKVYENEDQLLWCPDVVLESKVKEYLVETSLRTGSEKIMDRISAGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDETEALGGTVNASALTSNRPEPIPDQQLNILNSFTASDLTALTNSVATVCDPTDVNCLDDSFPPLGNTPRGQVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMNMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSANETNGFISAHALHQHAALHSE
Protein: Transcriptional-regulating factor 1 (Breast cancer anti-estrogen resistance 2) (Transcriptional-regulating protein 132) (Zinc finger protein rapa) (Zinc finger transcription factor TReP-132) (Q96PN7)
Organism: Homo sapiens (Human)
Function: Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:11349124, ECO:0000269|PubMed:16371131}.
Interaction partners:
- Deoxynucleotidyltransferase terminal-interacting protein 1
- Histone deacetylase 1
- Mitotic deacetylase-associated SANT domain protein
- Steroidogenic factor 1
Sequence:
MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
Protein: RH24480p (Q86LF6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVAQWKIINENYKNLEGYKRVAWPPASEERIIREFTPQPQTQSPAPGAGGYYPQAHAPTAAAAAPPQPQLPYSQDQTDLQQQQQQQQQQYPGAYAGQDSYRGASPGIITLRKEAPVSQKPAPVYTSQPAAVSYQGGSKLRGDLKWPPPEYKEAAARENEERRQLALGPVCRPRRVNRDYTPFFAKHQLNNGYPSYKVPPGTQHIFG
Protein: Cytoplasmic FMR1-interacting protein (D4A8H8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Synapse, synaptosome {ECO:0000256|ARBA:ARBA00034102}.
Interaction partners:
- Nck-associated protein 1
- Actin-binding protein WASF1
- Abl interactor 1
- Fxr2 protein
- NCK associated protein 1 like
- RNA-binding protein FXR1
- Eukaryotic translation initiation factor 4E
- Fragile X messenger ribonucleoprotein 1
- Protein BRICK1
- Abl-interactor 2
Sequence:
MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSSSSPQYNICEQMIQIREDHMRFISELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKDCPDNAEEYERATRYNYTTEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTKFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSLELAIGRFESEDLTSVVELDGLLEINRMTHKLLSRYLTLDSFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAVLFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERVDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRTFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITILDKYLKSGDGESTPVEHVRCFQPPIHQSLASS
Protein: Protein mono-ADP-ribosyltransferase PARP8 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 16) (ARTD16) (Poly [ADP-ribose] polymerase 8) (PARP-8) (Q8N3A8)
Organism: Homo sapiens (Human)
Function: Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
Interaction partners:
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL18
Sequence:
MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPRSVSYSVHVSEDYPDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCCLSIKSKLQKENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGLGHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKVKSPLHLFSTLRRSPSYPPPGCGKSKSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSSDPRAEQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEELYGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSSSSSQLAPNGAKCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIHKEILRVIGNQTATG
Protein: Suppressor of fused homolog (Q9VG38)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR011844}. Nucleus {ECO:0000256|PIRNR:PIRNR011844}.
Interaction partners:
- Kinesin-like protein costa
- Serine/threonine-protein kinase fused
- Transcriptional activator cubitus interruptus
- Protein smoothened
- cAMP-dependent protein kinase catalytic subunit 1
- cAMP-dependent protein kinase catalytic subunit 2
- Protein hedgehog
- Protein patched
- Serine/threonine-protein kinase ULK3
- Kinesin-like protein
Sequence:
MAEANLDKKPEVKPPPGLKAIIDHLGQVYPNQPNPLQVTTLLKYWLGGQDPLDYISMYNYPGDVDRNVPPHWHYISFGLSDLHGDERVHLREEGVTRSGMGFELTFRLAKTEIELKQQIENPEKPQRPPTWPANLLQAIGRYCFQTGNGLCFGDNIPWRKSLDGSTTSKLQNLLVAQDPQLGCIDTPTGTVDFCQIVGVFDDELEQASRWNGRGVLNFLRQDMQTGGDWLVTNMDRQMSVFELFPETLLNLQDDLEKQGSDLAGVNADFTFRELKPTKEVKEEVDFQALSEKCANDENNRQLTDTQMKREEPSFPQSMSMSSNSLHKSCPLDFQAQAPNCISLDGIEITLAPGVAKYLLLAIKDRIRHGRHFTFKAQHLALTLVAESVTGSAVTVNEPYGVLGYWIQVLIPDELVPRLMEDFRSAGLDEKCEPKERLELEWPDKNLKLIIDQPEPVLPMSLDAAPLKM
Protein: Response regulator (Q9WYT9)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Interaction partners:
Sequence:
MSKKVLLVDDSAVLRKIVSFNLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQEKEEWKRIPVIVLTAKGGEEDESLALSLGARKVMRKPFSPSQFIEEVKHLLNE
Protein: Myosin phosphatase targeting subunit 75D, isoform B (M9PFV2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MIKGILIQRKSQEDASYTKQLKMEHADLVAEMQTVESLPTHERLQLARLRRAQQLKLSRQKDKEWAKLQRAKGNTASGGSGTGSLGNGLMNGNGDTTHHFRHANGSGTLSGRRHISFENSVVLLEAASRNDMPEVAALLQHGITPDAANEDGLTAMHQACIDNNVEMLQLLLEYGANVDAQDSDKWTPLHAAATCGHLELVRILIRHGANLLAVNTDGNMPYDLCDDEKTLDFIEGEMAQRGVTQELIDETRSSTERIMLRDLMELARTGGDLEEPDYQCATPLHIAAANGYVRVVEFLLEQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDETPSDICEDPEIRERIEQLKTEQESKRLAEAQRRRVRRSQSNNTRAQSVRRTSLRDKTLTTKKDAVEETRLRLQAQEATDSEAPSSAGDPLTNGYGYGNNNGEKRPSTGSSNGQPLPHSKSADALDNATAALSANATHSYPSRRPPDGRENDELLRLKAAGAAGEMQRATSAAAVILTEKGTAASAEAVQIQSSKEAANGKINVQVTVLVGAGGSSSNNNNNLSTSNNNNNGSAPISTQPTLGHMGAGSVLSDFEGSSPAGSSLNKFSGITGDVVTDSTSSSRRCCVLM
Protein: Superoxide dismutase (EC 1.15.1.1) (B5Z862)
Organism: Helicobacter pylori (strain G27)
Interaction partners:
Sequence:
MFTLRELPFAKDSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFAILTKSSGGVFNNAAQIYNHDFYWDCLSPKATALSDELKGALEKDFGSLEKFKEDFIKSATTLFGSGWNWAAYNLDTQKIEIIQTSNAQTPVTDKKVPLLVVDVWEHAYYIDHKNVRPVYLEKFYGHINWHFVSQCYEWAKKEGLGSVDYYINELVHKKA
Protein: Zinc-finger homeodomain protein 7 (AtZHD7) (Homeobox protein 28) (AtHB-28) (Q9SVL0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription factor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm. {ECO:0000250}.
Interaction partners:
- Pathogenesis-related homeodomain protein
Sequence:
MELGGKCNAITTTTMISTEVKPHTDPEPEAKPESDPSMALFPIKKENQKPKTRVDQGAKYRECQKNHAASTGGHVVDGCCEFMAGGEEGTLGALKCAACNCHRSFHRKEVYGHRNSKQDHQLMITPAFYSSNSSYKPRVMHPTGEIGRRTSSSSEDMKKILSHRNQNVDGKSLMMMMMRKKKRVRTKINEEQKEKMKEFAERLGWRMQKKDEEEIDKFCRMVNLRRQVFKVWMHNNKQAMKRNNSNISE
Protein: Neurochondrin homolog (dNeurochondrin) (Q9VI25)
Organism: Drosophila melanogaster (Fruit fly)
Function: Strongly up-regulated in Mhc mutants suggesting a role in muscle function.
Interaction partners:
- LD15807p)
- Troponin C, isoform 3
Sequence:
MTDVPEPVRKCASLLKGTKSDTEKFAALFMVTKLVKGKDCNAAGKKLLFEAIGFPFLKKLLVSKDLPNDCPPLVYKSVALSILTCFCQEEELATHKDIIDAIPTLLEIVEQADDEDYEDNLIVVSEAYSCLKSIASHEPGQQALLATGAIPKMSQIYSAQSFQTDEALHLIVLLVKQFGVVSWPEDPTAFHALIQRIALDMETDDTERKYELCRILADILITCRREIVINSLEGQIWPESLFKGCGDILKAKIGPKQRDPALHLIATTLHVLGIQWAFMDEQKTFFLQLLQLGAIEVRMQMDEKKLETTFKQAELLTCCFSILEHCIEYMATDQLDLEPKEKQTTYTALKGAFNQVLAVLTRVSQDKIRESSNPKDKKFVFAIVKVLSAWLAQETTAMRPAIYKLLPFMLKVANESFQELKTWRAGTREGEPPIDVLRIMLPALCHFAVEEEARRVLFTHKQDEVLLESLEFYFSIAHWKRPPIPRAERLKRMNEPDPVPTPEQQAEMKVARSAIVALCNILMNFTVLEPKKAEDGPTFANLLKFVVENLPELKDTPDNLVIHGNLAVLGLLLLKQQSKKVKQNDFSICRYIQATIRFLWDAYNIDESNDPTALVVSIAYKGYWSDLSELWFLGMQTMCGVLPLVPWLSEFALESGWAEGIVKTLKKVKIGTLPANVKSAYEDFLSQLVDVNGDVQAVLKKADALRVCRNHRMMDLGKKLFGD
Protein: Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] (P54802)
Organism: Homo sapiens (Human)
Function: Involved in the degradation of heparan sulfate.
Subcellular location: Lysosome.
Interaction partners:
- Heparan-alpha-glucosaminide N-acetyltransferase
- N-sulphoglucosamine sulphohydrolase
- N-acetylglucosamine-6-sulfatase
- Transmembrane emp24 domain-containing protein 9
- Alpha-L-iduronidase
- Transmembrane emp24 domain-containing protein 10
- Transmembrane emp24 domain-containing protein 4
- 17-beta-hydroxysteroid dehydrogenase type 1
- Lysosome-associated membrane glycoprotein 2
- N-acetylgalactosamine-6-sulfatase
Sequence:
MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGELTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYLALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTPVLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELIKEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQFWGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGALEAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAARRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAWRLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAYELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPRWVAGSW
Protein: Aldose 1-epimerase (EC 5.1.3.3) (Q8MT28)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVNVTEDVFANGAVNPFTKSKDTIKRFTLTNGAGMSVQLITRGATITSIKTPDASGQIDDVTLGFDDLAGYQSERNPYFGATIGRVCNRIANGSFYLDGKLVQVSKNRDNKFQLHGGFVGFDKAHWEVVEVRVDGVTLSHTNPDGHEGYPGKVTATASFTLSEDNCLHVQMSALADKTTPVNLTNHSYFNLAGHKSGANGLYEHTIKINAYGITETDQSSIPTGRITPVEGTGFDLRVSSNLGERLKALQPARGYDDNFCVTFSPPQPLAKVARATHPPSGRWLEVVSNQPGVQFYTSNFMPDVERGESPIPGKDGAAYAKHCAFCLETQKFPDSVNHSNFPSTILRPGESYQHEVIYKFGVSH
Protein: Uncharacterized protein C651.12c (O94670)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Zinc finger SWIM domain-containing protein sws1
- Uncharacterized protein C22G7.03
- DNA repair protein rlp1
- DNA repair protein rdl1
Sequence:
MSSKKVKYNPRKSASQNEATSASAGSKAFGFNSAKKEKLHRMALSMEAIEDVEDQSFNGKSSNLVRKRRGLDEDIDEFSSSSEDERKPARHPQSSSQKPFASSTYNVELPTSPTKITNIGQSSPRALRYLSPESQRIKNAKMKSPISTHLAKYSIHHMGTPPSKPSFLSSSVSSPASSKQKSLFQCTKDLEKRYINRVHRSSETELVQLSSIKVLDRFLSDIYLVEAEKNEEKCTVLLLKRSNTDVDNSSSLSLTLPLCKFTKNGHQVHIHPC
Protein: Probable inactive tRNA-specific adenosine deaminase-like protein 3 (tRNA-specific adenosine-34 deaminase subunit ADAT3) (Q96EY9)
Organism: Homo sapiens (Human)
Interaction partners:
- tRNA-specific adenosine deaminase 2
- tRNA-specific adenosine deaminase 1
- Single-strand selective monofunctional uracil DNA glycosylase
- Thymidylate synthase
- Uracil phosphoribosyltransferase homolog
- Thymidine kinase, cytosolic
- tRNA
- 5'-nucleotidase
- tRNA
- Double-stranded RNA-specific adenosine deaminase
Sequence:
MEPAPGLVEQPKCLEAGSPEPEPAPWQALPVLSEKQSGDVELVLAYAAPVLDKRQTSRLLKEVSALHPLPAQPHLKRVRPSRDAGSPHALEMLLCLAGPASGPRSLAELLPRPAVDPRGLGQPFLVPVPARPPLTRGQFEEARAHWPTSFHEDKQVTSALAGRLFSTQERAAMQSHMERAVWAARRAAARGLRAVGAVVVDPASDRVLATGHDCSCADNPLLHAVMVCVDLVARGQGRGTYDFRPFPACSFAPAAAPQAVRAGAVRKLDADEDGLPYLCTGYDLYVTREPCAMCAMALVHARILRVFYGAPSPDGALGTRFRIHARPDLNHRFQVFRGVLEEQCRWLDPDT
Protein: SUMO1/Ulp2, putative (Q38FU0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Small ubiquitin protein, putative
- Las1-like
- Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop domain-containing protein
- Guanine nucleotide-binding protein subunit beta-like protein
- Leucine-rich repeat protein
- Importin subunit alpha
- Sperm-associated antigen 6
- Ribosome biogenesis protein BOP1 homolog
- Pescadillo homolog
- Importin beta-1 subunit, putative
Sequence:
MADILLNAAGWILPSLHRSRRAPTTSEETCEAGTNPCTPPLGQRPANEAGSRSVTPSPPPQQQSRATANDAAGDVYPSGHLCAHKRLKGKSSRHMGTSVIAKGMESLLRCILSEDKRDTPLSMSVADDSLSPLERDAAWTTPNNSQEITTESEKERQWQKLKISQPAARATYRLPDAQIEGSEHYSVEQLSTHSVGHVRQRFTSPYLSEWEKPMSLMCEPVHDRGDRFIMERTNNQLLPTSGKEAPKRPKQVREQHLSAAAASFKRQCRDAAENYGADVGRCIRDKRGDKLAACLRDVEGKLRGDSKGGSITSVTMNAEEKRQHLYPRWPQQYSALNDSNETLLRAVDTDVDRKVRYIYEIVLGDFVRSAVEVEARKCINFFNHMAQRALESYVMRALVAKVEPTSKSLVATKALSHGIRRHIECGKAAYICELAEDEDDRAVFETTLTTGKWDSSRSQNSGEQERVAVSLKSGIAITYRQLSTLAPGVWLNDQIINAYLGLICDEYNVRAGCEAAVSMGTHFYAKVQQEMRIGNAGLNPSSGGFPTLEQNSGVLRWLKRRRHILQSGTTRIVLVPVNLWQSHWTLAVLDWERNRWTYYDSLLYGNAPVPQGSTVLGALHHTFEEARRILCDSDDANSNHTVKAERGYQPRVNGAADQRRLTVATPVGSCCGYDATNGWFDVAPQQQNSSDCGVFVCHVAWCVVNGVALTFTQEDVTALRRVMLHELLLQRLLRRLPLALYTKA
Protein: Expression site-associated gene 9 (ESAG9) protein, putative (Q38EL2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMLMIATSLFLILMLCVAGVEQRVVSAVDVTMSRDSCTEYRTSPTTGVLECGTVTANRRSSTHQQNPPVTASAIQQPQSQLQEETSTQKPLGPRSTDSSSNGGNGSSHQTSKPQEKSPEVATELDDGQPHGSPESSVKSSNELPQANYVGAAAVTSDHQRVQAKKKMGDEGETKTRRENRQGNEEETQKFVPPPQVTGQDDRYVASPLRSAASEPEVSRPSDVVTSGTNETSSSKESEQRRNGVGHKRHAMILSTVLSFIIF
Protein: PHO85 cyclin-7 (PHO85-associated protein 1) (P40186)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Together with cyclin PCL6, controls glycogen phosphorylase and glycogen synthase activities in response to nutrient availablility. The PCL7-PHO85 cyclin-CDK holoenzyme has GLC8 kinase activity and phosphorylates and inactivates the phosphatase PP1-2 inhibitor GLC8, causing activation of PP1-2, which then dephosphorylates and activates glycogen phosphorylase. PCL7-PHO85 also phosphorylates MMR1 and YJL084C.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Cyclin-dependent protein kinase PHO85
- PHO85 cyclin-5
- Cyclin-dependent kinase 1
- PHO85 cyclin-9
- Proteasome subunit beta type-1
- Phosphate system positive regulatory protein PHO81
- PHO85 cyclin CLG1
Sequence:
MELSSPSKKTTTSPINIPGGNRDNLIIGPHSHSFKTDPFSSNNSSLLSKISTNPSLESPFSSKSLLDCSPVQAVKKSLESEAKTHSLDEETNEQTDVKILNIADFPTDELILMISALLNRIITANDETTDVSQQVSDETEDELLTPILAFYGKNVPEIAVVQYLERIQKYCPTTNDIFLSLLVYFDRISKNYGHSSERNGCAKQLFVMDSGNIHRLLITGVTICTKFLSDFFYSNSRYAKVGGISLQELNHLELQFLILCDFKLLVSVEEMQKYANLLYKFWNDQ
Protein: Trp operon repressor (P0A882)
Organism: Escherichia coli O157:H7
Function: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- DUF1145 family protein
- DUF1145 family protein
- Arginine repressor
- HTH-type transcriptional regulatory protein TyrR
- Arginine repressor
- HTH-type transcriptional regulatory protein TyrR
- Aromatic amino acid permease
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive
- Macrodomain Ter protein
- Macrodomain Ter protein
Sequence:
MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD
Protein: Protein PLANT CADMIUM RESISTANCE 2 (AtPCR2) (Q9LQU4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Zinc transporter acting in both zinc extrusion and long-distance zinc transport. Involved in the loading of zinc into the xyleme and in the detoxification of excess zinc at the epidermal cells. Acts independently from the zinc transporters HMA2 and HMA4. May be also involved in cadmium resistance.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20647347}; Single-pass membrane protein {ECO:0000269|PubMed:20647347}.
Interaction partners:
- Putative cadmium/zinc-transporting ATPase HMA4
- Cadmium/zinc-transporting ATPase HMA2
- Metal tolerance protein 1
- Chromo domain-containing protein LHP1
- Putative inactive cadmium/zinc-transporting ATPase HMA3
- Protein ZINC INDUCED FACILITATOR 1
Sequence:
MEAQHLHAKPHAEGEWSTGFCDCFSDCKNCCITFWCPCITFGQVAEIVDRGSTSCGTAGALYALIAVVTGCACIYSCFYRGKMRAQYNIKGDDCTDCLKHFCCELCSLTQQYRELKHRGYDMSLGWAGNVERQQNQGGVAMGAPVFQGGMTR
Protein: Ribosome quality control complex subunit TCF25 (TCF-25) (Transcription factor 25 homolog) (Q8T2A4)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May act as a transcriptional repressor.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9BQ70}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9BQ70}.
Interaction partners:
- E3 ubiquitin-protein ligase listerin
- DUF814 family protein
- RING-type domain-containing protein
Sequence:
MSTKALKKKQHINVQHVNSSSDEGSEKKVVVVVNSVKPKFSMLNLSDEDDDKSDQDENEDKKDSESEESEEEEEEEEIEKEKPQAKEQLSSKQQKQKQQQQASKKKQAKKKQQQKKKQQQQEKDELELNEIEKSSPPIILSEIEIKDKEFRELFKINTVNLNPDNELKKLFGCKSSDIKGQKKKSVHHFKKKNYIFVQPKPEWPDVMGGFMVMEICNDDKVPSSPTNATTTTTTTTTTTNTVSPKLKSQQQSLDGINYFKIKWGQTYSNIQEEFYLALTTHDPMSLVEIIRYHPYHIDSLLQLGQVCLQTADYSKAGDFVEMAVFAFENVFHHLFNPLNGNCRFEYRHDQNKSCFLAIFRFIQIIGRRACHRTALELCKILLTWDYSDPLYVRLIIDYYSIRSKQYRFLVDLFTKLKTITPTNQGDLSLLPNFCYSAALAMYHLEREKSTTTTSTSTSTSSSKSSSVEESSDILLQKALISFPMVLQPLLEKLKTNFSIPKNGKIITLENDPFFKDDPLEKRIDHLVTLFVERNYQCWQTPEILDWLKSNVIIVLDKVAAKHPMVKQLSDSIKAEYETVNQEVFDHLVLSEYSDVINRLTPDIIEAMHAEGFRDILPQRDPNQAPPQHLRRGGIGQGFQIHQRNQQQQRRVQQQLRQLQQQQQQNLQHQQQQPLEPLLQENPDYTGPANPVLNFLHSLLPWNDPSIQRERQLAATQGTQQPAPGFLDDYVDFSDEDENEN
Protein: Phospholipase A and acyltransferase 2 (EC 2.3.1.-) (EC 3.1.1.32) (EC 3.1.1.4) (HRAS-like suppressor 2) (Q9NWW9)
Organism: Homo sapiens (Human)
Function: Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor. Exhibits high phospholipase A1/2 activity and low N-acyltransferase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18163183}. Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. Note=Exhibits a granular pattern in the cytoplasm with preferential perinuclear localization. {ECO:0000269|PubMed:18163183}.
Interaction partners:
Sequence:
MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ