wanglab/gogpt-training-data huggingface dataset:
Protein: Cytoplasmic linker associated protein 2 (E7EW49)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKDKSFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGPKVGAGASKEGGAGAVDEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSLQRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRVRAKLSAPLAGMGNAKADSRGRSRTKMVSQSQPGSRSGSPGRVLTTTALSTVSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALLLGDIRTKKKPARRRYESYGMHSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHGKVFSMFLETLVDFIQVHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKVKVAILKYIETLAKQMDPGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRAGGDATDSSQTALDNKASLLHSMPTHSSPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDLSLDHSDLVAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGGADPTTDVSGQS
Protein: Rab40c, member RAS oncogene family (A0A8I5ZWU0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}.
Interaction partners:
Sequence:
MAAAHPGAGLRGCAVPCGKRRAAAAAAVAAAARRLRSGGGAVGRGAAGGRMGTQGSPVKSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNDSHTQGKVLELTGAKTRVYVYSGIDYKTTTILLDGRRVKLELWDTSGQGRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGSGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS
Protein: Protein LKAAEAR1 (LKAAEAR motif-containing protein 1) (Q8TD35)
Organism: Homo sapiens (Human)
Interaction partners:
- Transmembrane protein 191C
Sequence:
MPPPAKEGGRKGPRERSGKSAPGTAQGEERAKGAPATEPPKPGWALTPQGLAAMLPAQRHRHLLFGDLLEDVGAAASTFPCGSVEPGYRMPDPRPWTQSLELPAERQNRLLGVLKAAEARGRVRALRLRYTRMRAEEIALLIQRQKSARAAIRLELFLPPQLKPARIPDPLDRQERRRVETILEENVDGTIFPR
Protein: WUSCHEL-related homeobox 14 (Homeodomain protein PALE-2) (AtPALE2) (Q9LM84)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts redundantly with WOX4 downstream of the TDR/PXY receptor kinase to regulate procambial cell proliferation and differentiation in vascular tissue, independently of any role in vascular. Involved in the regulation of gibberellin (GA) biosynthesis pathway. Regulates positively the expression of the GA biosynthesis gene GA3OX1, and negatively regulates the expression of GA2OX1 during secondary growth, which increases bioactive GA content in the inflorescence stem. Promotes vascular cell differentiation in the inflorescence stem.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- CLAVATA3/ESR
- Leucine-rich repeat receptor-like protein kinase TDR
- CLAVATA3/ESR
- LOB domain-containing protein 4
- Dof zinc finger protein DOF5.3
- Protein CLAVATA 3
- CLAVATA3/ESR
- Leucine-rich repeat receptor-like protein kinase
- Leucine-rich repeat receptor-like protein kinase PXL1
- Probable leucine-rich repeat receptor-like protein kinase At5g05160
Sequence:
MVKKKKEKEKSKEIEEMDREIQNGAYSGRVMTEEQMEILRKQIAVYAVICDQLVLLHNSLSSYHPLSSGVRPMVGGYFDPMGASSSSHRISTRHRWTPTSTQLQILESIYDEGSGTPNRRRIREIATELSEHGQITETNVYNWFQNRRARSKRKQPQTTTANGQADDVAVTTEERRSCGDSGGLESYEHILFPSPDLGIEHLLSIGKFMET
Protein: RNA-binding protein, putative (Q38EA2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MYSQPFTQNSLYGAPNMMPYQNMMPPQVSQHGNPGMMQNYGNPGQGRGGFDAQKQPQQLQIGRQMVQRPPRTRNNEIGEVSRVIHMRNITPNVTQLSIQNLVQNFGNIKHIVMLRQMNQALVEMESTKSAQQLVDFFREAGYAEIDGRRVYIRYSNHQELTATQHTSKTLLVSMFNTQYDVSAATSITPMIVYQIFCNYGAVQKIVVLPKNESSQRNHNRVQALVQFDSKATAENVKNILQGQPVTIGETVTFTLDIQFSRMDNIKTSNPAISLVVNEDGVPQPPQPQPPQPPQQQQQQQPQQQPPPPPQQQQMQGNVYPGITQQWS
Protein: J domain-containing protein (Q387J4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- PRP8 protein homologue
- U5 small nuclear ribonucleoprotein component, putative
- RNA helicase
- PRP1 splicing factor N-terminal domain-containing protein
- Uncharacterized protein
- Spliceosomal U5 snRNP-specific protein, putative
- Pretranslocation protein, alpha subunit, putative
- Small nuclear ribonucleoprotein E
- Sm protein F
- Small nuclear ribonucleoprotein SmD1
Sequence:
MNRSCSRVTVLRGAPSALYLRAPHTVSVRLRRSAVASLLGPTFLRVQVRTQFAQIPGKRDQEAFLAQFNPLDVLGLNESCTVDDIDEAFKRMSAKYGPNGPTPNAQMVDRVFRAHEVLKDPASPYYLRAHSSDSDRQRLQFQLLPKRQRRLIKAQAGMLVLFLAGIAMLVISMTFRPVKRMLRAATR
Protein: Small capsomere-interacting protein (D3XDN6)
Organism: Murid herpesvirus 1 (strain Smith) (MuHV-1) (Mouse cytomegalovirus)
Subcellular location: Virion {ECO:0000256|HAMAP-Rule:MF_04021}. Host nucleus {ECO:0000256|HAMAP-Rule:MF_04021}.
Interaction partners:
Sequence:
MSTNVSSAASGGGSSGGSSGASSGGGGGGSGGSSKKEEERRKQFGANVLNLAPAMVAQPVISTMIPKYMKMGGHEDKLAYQLDLLRMLSIAKKATVIQ
Protein: Mitochondrial pyruvate carrier 1 (MPC1) (Protein FMP37) (P53157)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mediates the uptake of pyruvate into mitochondria.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Mitochondrion inner membrane {ECO:0000269|PubMed:22628554, ECO:0000269|PubMed:22628558}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Mitochondrial pyruvate carrier 2
- Mitochondrial pyruvate carrier 3
- NAD-dependent malic enzyme, mitochondrial
Sequence:
MSQPVQRAAARSFLQKYINKETLKYIFTTHFWGPVSNFGIPIAAIYDLKKDPTLISGPMTFALVTYSGVFMKYALSVSPKNYLLFGCHLINETAQLAQGYRFLKYTYFTTDEEKKALDKEWKEKEKTGKQ
Protein: Golgi to ER traffic protein 4 (Guided entry of tail-anchored proteins 4) (Q12125)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- ATPase GET3
- Ubiquitin-like protein MDY2
- Small glutamine-rich tetratricopeptide repeat-containing protein 2
- Maintenance of telomere capping protein 1
- Golgi to ER traffic protein 1
- UPF0303 protein YBR137W
- Golgi to ER traffic protein 2
- Heat shock protein 104
- Mitochondrial protein import protein MAS5
- SRP-independent targeting protein 2
Sequence:
MVPAESNAVQAKLAKTLQRFENKIKAGDYYEAHQTLRTIANRYVRSKSYEHAIELISQGALSFLKAKQGGSGTDLIFYLLEVYDLAEVKVDDISVARLVRLIAELDPSEPNLKDVITGMNNWSIKFSEYKFGDPYLHNTIGSKLLEGDFVYEAERYFMLGTHDSMIKYVDLLWDWLCQVDDIEDSTVAEFFSRLVFNYLFISNISFAHESKDIFLERFIEKFHPKYEKIDKNGYEIVFFEDYSDLNFLQLLLITCQTKDKSYFLNLKNHYLDFSQAYKSELEFLGQEYFNIVAPKQTNFLQDMMSGFLGGSK
Protein: Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) (Q2A865)
Organism: Rattus norvegicus (Rat)
Function: Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity.
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q695T7}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Angiotensin-converting enzyme 2
- Collectrin
- Neutral amino acid transporter B
- Amino acid transporter
- b
- Angiotensin-converting enzyme
- Y+L amino acid transporter 1
- Amino acid transporter heavy chain SLC3A2
- Excitatory amino acid transporter 3
Sequence:
MVRLVLPNPGLEDRIPSLDELEVIEKEEASSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSSIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNQNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSIINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTAENFEAYQHWCNATNPEAYAQLTFQTCDINTFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKQLMYSVWDPDYEEFPKSQKVPYPDWVYAVVVIVAGVPCLTIPCFAIYKLIRNYCQKSGDQHGLVNALSTASVNGDLKN
Protein: Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (dC stretch-binding protein) (CSBP) (P61980)
Organism: Rattus norvegicus (Rat)
Function: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest (By similarity). As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P61978}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:P61978}. Cell projection, podosome {ECO:0000250|UniProtKB:P61978}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoproteins C1/C2-like
- Heterogeneous nuclear ribonucleoprotein C
- Heterogeneous nuclear ribonucleoprotein A3
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Polypyrimidine tract-binding protein 1
- RNA-binding motif protein, X chromosome
- RNA binding motif protein, X-linked-like-1
- Heterogeneous nuclear ribonucleoprotein F
Sequence:
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF
Protein: E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (Muscle RING finger protein 1) (RING-type E3 ubiquitin transferase TRIM63) (Tripartite motif-containing protein 63) (Q38HM4)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15601779}. Nucleus {ECO:0000269|PubMed:15601779}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Localizes to the M- and Z-lines in skeletal muscle (By similarity). Colocalizes with TNNI3 in myocytes. {ECO:0000250}.
Interaction partners:
- Titin
- F-box only protein 32
- Forkhead box protein O1
- Telethonin
- Glucocorticoid receptor
- Myosin-1
- Nebulin
- Growth/differentiation factor 8
Sequence:
MDYKSGLIPDGNAMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTNRGGSVSMSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHPMCKEHEDEKINIYCLTCEVPTCSLCKVFGAHQACEVAPLQSIFQGQKTELSNCISMLVAGNDRVQTIISQLVDSCRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEEKLGFIEALILQYREQLEKSTKLVETAIQSLDEPGGATFLSSAKQLIKSNVEASKGCQLGKTEQGFENMDYFTLDLEHIAEALRAIDFGTDEEEEEFTEEEADEEEGVTTEGHQ
Protein: Calcium-dependent protein kinase 28 (EC 2.7.11.1) (Q9FKW4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger (Probable). Acts as developmentally controlled regulator for coordinated stem elongation and vascular development. Acts as key component which contributes to the developmental switch that establishes the transition from vegetative to reproductive growth. Involved in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling. Interacts with and phosphorylates the kinase BIK1, a central rate-limiting kinase in PTI signaling. Facilitates BIK1 turnover and negatively regulates BIK1-mediated immune responses triggered by several PAMPs. Its kinase activity is necessary and sufficient for its function in PTI signaling.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12913141}; Lipid-anchor {ECO:0000269|PubMed:12913141}.
Interaction partners:
- Respiratory burst oxidase homolog protein D
- U-box domain-containing protein 25
- U-box domain-containing protein 26
- Extra-large guanine nucleotide-binding protein 2
- Probable E3 ubiquitin-protein ligase ATL44
- At4g34150 family protein)
- At1g58420
- Probable protein phosphatase 2C 38
Sequence:
MGVCFSAIRVTGASSSRRSSQTKSKAAPTPIDTKASTKRRTGSIPCGKRTDFGYSKDFHDHYTIGKLLGHGQFGYTYVAIHRPNGDRVAVKRLDKSKMVLPIAVEDVKREVQILIALSGHENVVQFHNAFEDDDYVYIVMELCEGGELLDRILSKKGNRYSEKDAAVVVRQMLKVAGECHLHGLVHRDMKPENFLFKSAQLDSPLKATDFGLSDFIKPGKRFHDIVGSAYYVAPEVLKRRSGPESDVWSIGVITYILLCGRRPFWDRTEDGIFKEVLRNKPDFSRKPWATISDSAKDFVKKLLVKDPRARLTAAQALSHAWVREGGNATDIPVDISVLNNLRQFVRYSRLKQFALRALASTLDEAEISDLRDQFDAIDVDKNGVISLEEMRQALAKDLPWKLKDSRVAEILEAIDSNTDGLVDFTEFVAAALHVHQLEEHDSEKWQLRSRAAFEKFDLDKDGYITPEELRMHTGLRGSIDPLLDEADIDRDGKISLHEFRRLLRTASISSQRAPSPAGHRNLR
Protein: 4-pyridoxolactonase (EC 3.1.1.27) (Q988B9)
Organism: Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099))
Function: Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Hydrolyzes 4-pyridoxolactone to 4-pyridoxic acid. Has lower activity toward N-hexanoyl-D,L-homoserine lactone, but is not active toward 5-pyridoxolactone and gamma-butyrolactone.
Interaction partners:
Sequence:
MSDTKVYLLDGGSLVLDGYHVFWNRGPGGEVRFPVYSILIEHAEGRFLIDTGYDYDHVMKVLPFEKPIQEKHQTIPGALGLLGLEPRDIDVVVNSHFHFDHCGGNKYFPHAKKICHRSEVPQACNPQPFEHLGYSDLSFSAEAAEARGATAQLLEGTTRANSTFEGIDGDVDLARGVKLISTPGHSIGHYSLLVEFPRRKPILFTIDAAYTQKSLETLCQAAFHIDPVAGVNSMRKVKKLAEDHGAELMYSHDMDNFKTYRTGTQFYG
Protein: Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)] (P01133)
Organism: Homo sapiens (Human)
Function: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Receptor tyrosine-protein kinase erbB-2
- Epidermal growth factor receptor
- Receptor tyrosine-protein kinase erbB-4
- Receptor tyrosine-protein kinase erbB-3
- Protransforming growth factor alpha
- Amphiregulin
- High affinity nerve growth factor receptor
- Insulin-like growth factor 1 receptor
- Insulin-like growth factor 1
- Growth factor receptor-bound protein 2
Sequence:
MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPHQMELTQ
Protein: Microtubule-associated protein 70-1 (AtMAP70-1) (70 kDa microtubule-associated protein 1) (Q9C9X0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant-specific protein that interact with microtubules. In association with MAP70.5, is essential for the normal banding pattern of secondary cell wall and for the proper development of xylem tracheary elements and wood formation.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15860013, ECO:0000269|PubMed:17567681, ECO:0000269|PubMed:20399097}. Cytoplasm, cytoskeleton, phragmoplast {ECO:0000269|PubMed:15860013}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:15860013}. Note=Associated with microtubules in interphase arrays, preprophase bands, spindles, and phragmoplasts. Associated with microtubules in tracheary elements. {ECO:0000269|PubMed:15860013}.
Interaction partners:
- AT5g59210/mnc17_100
- 65-kDa microtubule-associated protein 1
- Plasma membrane-associated cation-binding protein 2
- 65-kDa microtubule-associated protein 8
- 65-kDa microtubule-associated protein 5
- 65-kDa microtubule-associated protein 6
- Microtubule-associated protein RP/EB family member 1A
Sequence:
MSDVSADGGFLSAEQATTPVAIPTPYPSLTVSASYKEKSSGRRRPVRPSFDAAADNEFITLLHGSDPVKVELNRLENEVRDKDRELSEANAEIKALRLSERQREKACEELTDELAKLDGKLKLTESLLQSKNLEIKKINEEKKASMAAQFAAEATLRRVHAAQKDDDMPPIEAILAPLEAELKLARSEIGKLQEDNRALDRLTKSKEAALLDAERTVETALAKAALVDDLQNKNQELMKQIEICQEENKILDRMHRQKVAEVEKLTQTVRELEEAVLAGGAAANAVRDYQRKFQEMNEERKTLDRELARAKVTANRVATVVANEWKDGNDKVMPVKQWLEERRFLQGEMQQLRDKLAISDRAAKSEAQLKDKFQLRLRVLEETLRGTSSISIRNTPEGRSMSNGPSRRQSIGGSDNLQKFASNGFLSKKTPMRNSFTSNSTSVLKNAKGTSKSFDGGTRSLDRGKALLKGPGNYSFNKACDETKESESPNTWKEDSEEKPPSELPAPATEDNVPGVLYDLLQKEVVALRKSSHEKDQSLKDKDDAIEMLAKKVETLTKAMEVEAKKMRREVAAMEKEVAAMRVDKDQDNRAKRSSNTKPSSNTAQILAARAAGRSGLTRSTQ
Protein: Gonadal somatic cell derived factor isoform X2 (Gonadal somatic cell-derived factor) (A0A0R4IHC8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MLLRLVLLLLAFPLGEMFVLHPSPEDQSHREQEIKKIILKSLHLPKEPSNSLSQLEHLRESLKNSIHSPPGNSSLPEDSGNSSCCRRSSQVLMKDLGWDGWVVLPESVAFVQCVSCGSGTSVQCCKPTAHHIVPFVYMDASGLVLSTVRLPRDCGCDLAEDTLDPAAMSPP
Protein: AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog) (Q8WV93)
Organism: Homo sapiens (Human)
Function: Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain. Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress.
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:26759378}.
Interaction partners:
- ATPase family gene 2 protein homolog A
Sequence:
MAASWSLLVTLRPLAQSPLRGRCVGCGAWAAALAPLATAPGKPFWKAYTVQTSESMTPTATSETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFSKLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRLKQSLPKRKPGFMAKSYDPIAPIAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFKNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKEYCNTVQLDSGIDYRKRELPAAGKLYYLTSEADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASDYLELSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQHHDSELEQSRILMDDLGLSQDSAEGLSMFTGEEEIFAFQRTISRLTEMQTEQYWNEGDRTKK
Protein: GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (Q5H8A4)
Organism: Homo sapiens (Human)
Function: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15632136}; Multi-pass membrane protein {ECO:0000269|PubMed:15632136}.
Interaction partners:
- Transmembrane emp24 domain-containing protein 10
- GPI ethanolamine phosphate transferase, stabilizing subunit
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit A
- GPI alpha-1,4-mannosyltransferase I, catalytic subunit
- GPI alpha-1,2-mannosyltransferase 3
- GPI-anchor transamidase
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit H
- N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
- GPI alpha-1,6-mannosyltransferase 2
Sequence:
MRLGSGTFATCCVAIEVLGIAVFLRGFFPAPVRSSARAEHGAEPPAPEPSAGASSNWTTLPPPLFSKVVIVLIDALRDDFVFGSKGVKFMPYTTYLVEKGASHSFVAEAKPPTVTMPRIKALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKLFPKHFVEYDGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLGLDHIGHISGPNSPLIGQKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSETGSHGASSTEEVNTPLILISSAFERKPGDIRHPKHVQQTDVAATLAIALGLPIPKDSVGSLLFPVVEGRPMREQLRFLHLNTVQLSKLLQENVPSYEKDPGFEQFKMSERLHGNWIRLYLEEKHSEVLFNLGSKVLRQYLDALKTLSLSLSAQVAQYDIYSMMVGTVVVLEVLTLLLLSVPQALRRKAELEVPLSSPGFSLLFYLVILVLSAVHVIVCTSAESSCYFCGLSWLAAGGVMVLASALLCVIVSVLTNVLVGGNTPRKNPMHPSSRWSELDLLILLGTAGHVLSLGASSFVEEEHQTWYFLVNTLCLALSQETYRNYFLGDDGEPPCGLCVEQGHDGATAAWQDGPGCDVLERDKGHGSPSTSEVLRGREKWMVLASPWLILACCRLLRSLNQTGVQWAHRPDLGHWLTSSDHKAELSVLAALSLLVVFVLVQRGCSPVSKAALALGLLGVYCYRAAIGSVRFPWRPDSKDISKGIIEARFVYVFVLGILFTGTKDLLKSQVIAADFKLKTVGLWEIYSGLVLLAALLFRPHNLPVLAFSLLIQTLMTKFIWKPLRHDAAEITVMHYWFGQAFFYFQGNSNNIATVDISAGFVGLDTYVEIPAVLLTAFGTYAGPVLWASHLVHFLSSETRSGSALSHACFCYALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITAAVCVFFTAMDQTRLTQS
Protein: Protein unc-1 (Uncoordinated protein 1) (Q21190)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Cell junction, gap junction {ECO:0000269|PubMed:27015090}. Note=Co-localizes with unc-9 at the gap junctions formed between PLM and other neurons. {ECO:0000269|PubMed:27015090}.
Interaction partners:
- Innexin unc-9
- Innexin unc-7
- Degenerin unc-8
- Nematode cuticle collagen N-terminal domain-containing protein
- Sodium/potassium-transporting ATPase subunit beta-1
Sequence:
MSNKERTEPQWVTPSSNQDVPPDYETIGTIFGYALQALSWILIIVTFPFSMCVCLKVIKEYERVVIFRIGRLVFGGARGPGMIFIIPCIDTYRKIDLRVVSYAVPPQEILSKDSVTVSVDAVVYFRTSDPIASVNNVDDAIYSTKLLAQTTLRNALGMKTLTEMLTEREAIAQLCETILDEGTEHWGVKVERVEVKDIRLPQQLTRAMAAEAEAAREARAKVVAAEGEQKASRALKEAADVIQANPVALQLRHLQALNSIAAEHNSTIVFPVPVEMFGAFMKKDQ