wanglab/gogpt-training-data huggingface dataset:
Protein: Protein GAL3 (P13045)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: The GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease.
Interaction partners:
- Galactose/lactose metabolism regulatory protein GAL80
- Bifunctional protein GAL10
- Galactose-1-phosphate uridylyltransferase
- Regulatory protein GAL4
- Galactose transporter
- Galactokinase
- Phosphoglucomutase 2
- Uncharacterized isomerase YNR071C
- Regulatory protein MIG1
- Uncharacterized isomerase YHR210C
Sequence:
MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIVSKPALGTCLYEQ
Protein: Mycobactin import ATP-binding/permease protein IrtA (A0A100XEC2)
Organism: Mycolicibacterium thermoresistibile (Mycobacterium thermoresistibile)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004429}.
Interaction partners:
- Drug ABC transporter ATP-binding protein
- Phenyloxazoline synthase MbtB
- Polyketide synthase pks13
- Polyketide synthase pks5
- Bifunctional enzyme mbtA: salicyl-AMP ligase + salicyl-S-arcp synthetase
- Beta-ketoacyl synthase
- Linear gramicidin synthetase subunit D
- Linear gramicidin synthetase subunit D
- ATPase central domain-containing protein
- Beta-ketoacyl synthase
Sequence:
MARGFQGVMLRGLGARDHQATVVDKEYIAPHFVRVRLVSPTLFDEVIVEPTSWLRFWFPDPDGSDTEFQRAYTITESDPETGRFAVDMVLHEPAGPASTWARTVEPGATIAVMSMGSRGFSVPEDPEDRPVGYLLIGDSASTPAINGIIEVVPHDIPIELYLEQHHDDDVLIPLAEHPRLRVHRVSRDDASSLAAALELRDWSNWYCWAGPEAGALKQVRTRLRDEFGFPKREVYAQAYWTEGRAMGSSRGETSTPAKPAAKTAPAKAAAKPAAASGAGTPEHAAAPAAATTGAPQAAPAPGAAQPRTPVRGRWRAEAGSRLLAPLKKPLIVSGVLQALITLIELAPFVLLVELARLLLGGAEAERLWTLGLTAVSLIGLGAVLAAAMTLWLHRVDARFAHELRGRLLTKLSRLPLGWFTRRGSASTKQLVQDDTLALHYLITHAIPDAVAAVVAPVAVLVYLFVADWRVALVLFIPVLVYLVLMSVMTIQSGSKIAQAPRWAERMGGEAGAFLEGQPVIRIFGGAAASRFRRRLDDYIDFLVSWQRPFVGKKTLMDLVTRPATFLWIILVAGVPLVVTGRMDPVNLLPFLLLGTTFGARLLGIGYGLSGIQTGMLAARRIQTVLDEPELVVRDRTGQAGTDHASGDQARPGTVELDRVSFEYRPGVPVIRDVTLTLRPGTVTALVGPSGSGKSTLAALVARFHDVTQGAIRVDGRDIRTLTADELYRRVGFVLQDAQLVHGSVAENIALAEPDAGLERIRTAARDAQIHDRITRMPDGYDSVLGAGSALSGGERQRVTIARAILADTPVLVLDEATAFADPESEYLVQQAINRLTRDRTVLVIAHRLHTITHADQIVVLDDGRIVEVGTHDELLAAGGRYRGLWDSGRYSSPDAGRPVSADAVEVGR
Protein: AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) (Q9DBT5)
Organism: Mus musculus (Mouse)
Function: AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.
Interaction partners:
- Adenine phosphoribosyltransferase
- Adenylosuccinate lyase
- Adenylosuccinate synthetase isozyme 2
- Adenosine kinase
- Adenylosuccinate synthetase isozyme 1
- Inosine-5'-monophosphate dehydrogenase 2
- Bifunctional purine biosynthesis protein ATIC
- Inosine-5'-monophosphate dehydrogenase 1
- Hypoxanthine-guanine phosphoribosyltransferase
- Inosine triphosphate pyrophosphatase
Sequence:
MASYPGPGKSKAKYPFKKRAGLQASAAAPEARSGLGASPLQSARSLPGNAPCLKHFPLDLRTSMDGKCKEIAEELFSRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRGLWERDVVLEREFQRVIISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQSPDTPVSADAPVHPPALEQHPYEHCEPSAMPGDLGLGLRMVRGVVHVYTRRDPDEHCPEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNKISGKYFAHIIKEVMADLEESKYQNAELRLSIYGRSRDEWDKLARWAVNHKVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEVGIVMSPGP
Protein: Leucine-rich-repeats and calponin homology domain protein, isoform B (Q9VJE6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAATVYQRLHSVAVGVGSAAGSAIGSGSASLPGSGTGSGSGIGHAGNTSSSTSSALLSHSQLTRSLERILEEAHFSGELILTNRKLKDFPRTGTKYSLTDTVIADLSRNRFAELPEEVTTFAFLETLLLYHNTIRSIPESVKQLSSLTYLDLRSNQLSSLPREICFLPLQVLLVSNNRLTSLPDELGRLDQTLTDLDASYNQLANLPARLGELRSLRSLSLRSNHLLYLPRELTCLSLISLDVSNNKIASLPLEIRHMSTLVELQLENNPLTSPPASLCMRGLVHVFKFLETQATKDEKGSRSGGNYDGYTTLRRAPRHNSSGNVLEASTTGSTNNQRRHQVDSGYNTSDGLDKRWSHDAPTKSKTDSPLHCVSNSTAATLPRTLPSAVHSQADLMDASLTSSTSTIVDESLTLSPTASPCKLSYAHSNSSSNGSSPDQDDDIMLDHQERTVHHANGRSGKGLGNIQTYKEYKEALKQQRNQEISVYKQKHPNANHSPNDDEDLSPSPPSISNGSSSNTLPKSIMKQNSNQIGHNGNGNGSANGNGVDDVVIPKKPIQKVIPSRITEIKPASTSDIRSANSSDCLGYVKPQSPMKNGTSKFNTSNGGGVQTTVGIVSSTTIKSPVSSTTKLGTVKTHRSVTWNHDIPAEKLSFTMRREFDRQREETELMSQLRTIIETRLKMTLPVDIASALTDGVILCHLANYVRPRSVASIHVPSPGVNKLTMARCRRNVDNFLEACRRIGVDEELICSCEDVVPQIEPQQPQLPRADDDYDADVYVQDDGSISRSNDSSHLQCSDDCNSSSNHINRVPNALALLRTVSALIAMDENPYHQQLHHHLQLQLEQQHFEQEQFSEPTTCSQQQEQMLLLQQQQQQLEHVLYENGLPRAENDDGVEDRDDDIGKRQQQLATVGQMLLKAKQKTYEKIKHNLLSAHGQHNFQGNNNNRMLHTIVENEHDVAAAGPAGHYQIIDEKQEEDPYQPKSEDLKDAAALGNATKEAISKRIEFFEQQKSGKPKLEVFSIYLPKEKTKELELEQKIKAKTNEAGSSILKHDSHTLTVILSCVFIATFLWLNLICCAADVLEGKGAVQVAITVGELFRLHGNGGCGSGNSSGAATPTKSPTRTTRATMSPTPLA
Protein: THO complex subunit 4C (ALYREF homolog 3) (AtALY3) (Q94EH8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Export adapter involved in nuclear export of spliced and unspliced mRNA.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:11432957, ECO:0000269|PubMed:15299117}. Nucleus, nucleolus {ECO:0000269|PubMed:15299117}.
Interaction partners:
- THO complex subunit 4B
- Protein mago nashi homolog
- RNA-binding protein Y14
- DEAD-box ATP-dependent RNA helicase 15
- THO complex subunit 2
- THO complex subunit 3
- THO complex subunit 5A
- THO complex subunit 5B
- THO complex subunit 1
- Histone deacetylase complex subunit SAP18
Sequence:
MSDALNMTLDEIVKKSKSERSAAARSGGKGVSRKSGRGRGGPNGVVGGGRGGGPVRRGPLAVNTRPSSSFSINKLARRKRSLPWQNQNDLYEETLRAVGVSGVEVGTTVYITNLDQGVTNEDIRELYAEIGELKRYAIHYDKNGRPSGSAEVVYMRRSDAIQAMRKYNNVLLDGRPMKLEILGGNTESAPVAARVNVTGLNGRMKRSVFIGQGVRGGRVGRGRGSGPSGRRLPLQQNQQGGVTAGRGGFRGRGRGNGGGRGNKSGGRGGKKPVEKSAADLDKDLESYHAEAMNIS
Protein: Serine/threonine-protein kinase YPK3 (EC 2.7.11.1) (Ribosomal S6 kinase homolog YPK3) (S6K homolog YPK3) (P38070)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: AGC kinase which plays a role in TOR complex 1 (TORC1) signaling pathway which mediates temporal control of cell growth in response to nutrients. Required for phosphorylation of ribosomal protein S6 (RPS6A/RPS6B) at 'Ser-232' and 'Ser-233'.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Small ribosomal subunit protein eS6A
- Serine/threonine-protein kinase TOR1
- cAMP-dependent protein kinase regulatory subunit
- Serine/threonine-protein kinase TOR2
- Serine/threonine-protein kinase SCH9
- Mitogen-activated protein kinase HOG1
- Mitogen-activated protein kinase KSS1
- Mitogen-activated protein kinase FUS3
- Eukaryotic initiation factor 4F subunit p150
- Eukaryotic initiation factor 4F subunit p130
Sequence:
MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFSITGSDAMRTNTNRLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVITDLELAENFDTEFTSMSYEETYTDSKPININSVSKSPDMFKGFSYKASGSYLEKYF
Protein: Rifin (Q8IJ01)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKLYYFKILLFSLLLNILAHNKNKSYIAPHIPTTTTRVLSECNVYIPNYDNDPDMNSVRENFHKKTEQRFHEYDKRMIKNRQKRKEERDKNIQEIIEKDRMDKSLAEKVEKGCLKCGCGLGGVAASIGIFGTIAVNEWTKAATAAAIDLAIQEGIDAGVKVVIAEIKATNAFKSIWYVELSSFINGSNYNTVDGLSAATKAALDSIGKRCTSSIVDRACNGILNNSDGWFSSIAEAGKQAATAATESAKTTKLVDVTTTSTHLYSAIGYSVLAIFIILLVMVIIYLILRYRRKKK
Protein: CYRIA/CYRIB Rac1 binding domain-containing protein (Q09387)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}.
Interaction partners:
Sequence:
MPSNIRESDASCLEMIRSIIRSTADDNSKWVEIFVDFENAQPTDEEREIYNMAEEVLNDCDLVLADVSSYGNGCYAERNQLKNDSDTQALKVLMTKLEPFVARTCSYYEHVAKIEKIVPIILWELSSGPLPLEEQLANKQSIAKQFARLIGFVLDFDVVKMRTAQITNDYSYYRRAKHIVYQDFEDQGVPELPQVQMFLCEGNPMLKALCNGVDSYMQTHQSLPINNTTDVFVTIINVCRFMLANDECLARLTDSSKHLCCRVMTGLVILFDHVDQNGAFVSNSSIDMRDVVRLIKLNTTPEQSDCLLAGLRFTTKHYNDSSTPKSLRHLIEVK
Protein: Small ribosomal subunit protein bS18m (28S ribosomal protein S18-1, mitochondrial) (MRP-S18-1) (28S ribosomal protein S18c, mitochondrial) (MRP-S18-c) (Mrps18-c) (S18mt-c) (Small ribosomal subunit protein bS18c) (Q9Y3D5)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25838379}.
Interaction partners:
- Small ribosomal subunit protein uS11m
- Large ribosomal subunit protein mL66
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein mS33
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein uS2m
Sequence:
MAAVVAVCGGLGRKKLTHLVTAAVSLTHPGTHTVLWRRGCSQQVSSNEDLPISMENPYKEPLKKCILCGKHVDYKNVQLLSQFVSPFTGCIYGRHITGLCGKKQKEITKAIKRAQIMGFMPVTYKDPAYLKDPKVCNIRYRE
Protein: Anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase (A3G2''XylT) (EC 2.4.2.51) (Q9LVW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Contributes to the last few anthocyanin biosynthetic steps. Converts cyanidin 3-O-glucoside to cyanidin 3-O-xylosyl(1->2)glucoside. Can use 3-O-glucosylated anthocyanidins/flavonols and uridine diphosphate (UDP)-xylose as substrates.
Interaction partners:
- Dihydroflavonol 4-reductase
- Leucoanthocyanidin dioxygenase
- Flavonoid 3'-monooxygenase
- Naringenin,2-oxoglutarate 3-dioxygenase
- UDP-glycosyltransferase 75C1
- Transcription factor MYB75
- 2-oxoglutarate
- Chalcone synthase
- Transcription factor TT8
- Malonyl-CoA:anthocyanidin 5-O-glucoside-6''-O-malonyltransferase
Sequence:
MGVFGSNESSSMSIVMYPWLAFGHMTPFLHLSNKLAEKGHKIVFLLPKKALNQLEPLNLYPNLITFHTISIPQVKGLPPGAETNSDVPFFLTHLLAVAMDQTRPEVETIFRTIKPDLVFYDSAHWIPEIAKPIGAKTVCFNIVSAASIALSLVPSAEREVIDGKEMSGEELAKTPLGYPSSKVVLRPHEAKSLSFVWRKHEAIGSFFDGKVTAMRNCDAIAIRTCRETEGKFCDYISRQYSKPVYLTGPVLPGSQPNQPSLDPQWAEWLAKFNHGSVVFCAFGSQPVVNKIDQFQELCLGLESTGFPFLVAIKPPSGVSTVEEALPEGFKERVQGRGVVFGGWIQQPLVLNHPSVGCFVSHCGFGSMWESLMSDCQIVLVPQHGEQILNARLMTEEMEVAVEVEREKKGWFSRQSLENAVKSVMEEGSEIGEKVRKNHDKWRCVLTDSGFSDGYIDKFEQNLIELVKS
Protein: Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b) (O60315)
Organism: Homo sapiens (Human)
Function: Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Represses expression of MEOX2.
Subcellular location: Nucleus {ECO:0000269|PubMed:16061479, ECO:0000269|PubMed:9853615}. Chromosome {ECO:0000269|PubMed:20516212}.
Interaction partners:
- Cadherin-1
- C-terminal-binding protein 1
- Zinc finger E-box-binding homeobox 1
- Vimentin
- Mothers against decapentaplegic homolog 3
- Histone deacetylase 1
- Rho GTPase-activating protein 31
- Twist-related protein 1
- C-terminal-binding protein 2
- Protein Churchill
Sequence:
MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQETSPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTMGPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
Protein: Dipeptidyl-peptidase V (Q2URT4)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Interaction partners:
Sequence:
MTIRPMKFTPEVLLGAPRRSAAVPNSSGTLAVYTQTSYSFESHAKTSEIRVLDITTGRSSLITNDPSASSPQWLGNDDRLIWLKTKANGNTSFIVGHAREAGKTYTAGTVPGPVANLKVTVIESGKIGFAVTGKANPDGSLHNPQDAKKPHTTGRLYSSLYVRHWDSYIEPQTNSIWYGLLQQAPLTPATRHAGKYSTSALTNLISVCGLTGVESPIPPFGGSGDFDISPSAIVFVAKDPNENPATHTSCSCYYCPMFSWTSVTAMESQKIYAVKGLQGAMSSPVLSSDGSSIALLAMREDGYESDKNRILYVPNPWSGEMIEAFASPDGEGLWHLSPSAVTFANDDQSLLVQVEENGRGVLYQLPIANFRHSRPSALKKLTHSGYVTDVFPASANSSKLLVASNSLVENSRWTIIDPQSPESPKVISSLSRGGAAFGLSPAQVDEIWFRGAKDHPVHAWVVKPSDFKPGNKYPLAYLIHGGPQGAWNDQWSTRWNPAVFAEQGYVVITPNPTGSTGYGQAFTDAIRGSWGGLPYIDLEKGLDYIEKNLDYVDTTRAVALGASFGGYMVNWIQGHELGRRFKALVTHDGIFSMRSLLSTEELYFPVRDLQGPYWKVPENWDKWDPSRFTGNWQTPHLVIHNELDYRLTIAEGLAAFNVLQMRGVDSQFLTFPDENHWVLNPENSLMWHRTIFNFINKYVGLPSESRADLENGVANMSL
Protein: Histone deacetylase 2 (Q381M6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Trans sialidase, putative
- C2H2-type domain-containing protein
- Uncharacterized protein
- Histone-binding protein RBBP4-like N-terminal domain-containing protein
- Uncharacterized protein
- Guanine nucleotide-binding beta subunit-like protein
- Histone deacetylase, putative
- histone deacetylase
- Histone H2A
- Structural maintenance of chromosomes protein
Sequence:
MVVEPPASIPPVAVIVSTDVDAPASLPALQHNKLIIDMVRHYGCTPFPRKEVGGEAAFCNDIFEWVDRNLPSVDVEDMTVFHDESYVRYLSLREVASGDDEHVLSFSGCSNIRGTPSKRFASRRCSAPLPPFVLFPQNGDKRFNLVGDSAPFSGMWRFTQAVVSGTLAATRLLAQPSRFAAIHWMGGKHNAKRASAGGSCLVNDVVLAVLELRKLLPANRNVVLAVDLDAHHGDGAQEAFLSDPRVVTLSLHAYGIGIFPGTGSLEEIGSGLGRGYTMNIPLPVGATDALVVPMAQRGIYSAFRRAGVELGAVVVVCGSNSLSGDPYGLLNLTIGGYQRILRTLLTESASHSAKVLMLGGSCNVDVVAARLAGVLTRDVFSCATALRNGETSYFSWSPDLSTDKGVEVPEDCEYFTMYGPSFLMHSLPLAVVDEVHHFPPDSVLFSRMRQIAAKGERNSQMRDRAARKTVIEDDEEEESESEEEDTDEEEETESEGDENTSSQEGTDEEVVIDEDEETNGEGDEDTSSQEGNDEEEDTDETVLTDHVREGFPCLKERICGSLSEGQ
Protein: superoxide dismutase (EC 1.15.1.1) (Nitrite reductase CYGB) (Pseudoperoxidase CYGB) (Superoxide dismutase CYGB) (Q5QRU6)
Organism: Gallus gallus (Chicken)
Interaction partners:
- Neuroglobin
- GLOBIN domain-containing protein
Sequence:
MSFSEAEVQSARGAWEKMYVDAEDNGTAVLVRMFTEHPDTKSYFTHFKGMDSAEEMKQSDQVRGHGKRVFTAINDMVQHLDNTEAFLGILNPLGQKHATQLKIDPKNFRIICDIILQLMEEKFGGDCKASFEKVTNEICTHLTNIYKEAGW
Protein: UPF0718 protein YraQ (P45468)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Arsenical resistance operon repressor
- Anaerobic sulfatase-maturating enzyme homolog YdeM
- Putative RNA-guided DNA endonuclease InsQ
Sequence:
MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWEPYYGKAFTAAETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLRTLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPATLVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFSRWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVIPTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAVSGVIVGGLALLF
Protein: Ifngr2 protein (Interferon gamma receptor 2) (Q63953)
Organism: Mus musculus (Mouse)
Interaction partners:
- Interferon gamma
- Tyrosine-protein kinase JAK2
- Interferon gamma receptor 1
- Tyrosine-protein kinase JAK1
- Interferon alpha/beta receptor 1
- Signal transducer and activator of transcription 1
- Non-receptor tyrosine-protein kinase TYK2
- Interferon alpha/beta receptor 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Tyrosine-protein kinase JAK3
Sequence:
MRPLPLWLPSLLLCGLGAAASSPDSFSQLAAPLNPRLHLYNDEQILTWEPSPSSNDPRPVVYQVEYSFIDGSWHRLLEPNCTDITETKCDLTGGGRLKLFPHPFTVFLRVRAKRGNLTSKWVGLEPFQHYENVTVGPPKNISVTPGKGSLVIHFSPPFDVFHGATFQYLVHYWEKSETQQEQVEGPFKSNSIVLGNLKPYRVYCLQTEAQLILKNKKIRPHGLLSNVSCHETTANASARLQQVILIPLGIFALLLGLTGACFTLFLKYQSRVKYWFQAPPNIPEQIEEYLKDPDQFILEVLDKDGSPKEDSWDSVSIISSPEKERDDVLQTP
Protein: Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog) (A0A8I5ZVD6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03046}.
Interaction partners:
Sequence:
MKNIFQVSKMNKDAQMRAAINQKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEHVTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL
Protein: Prospero homeobox 1 (A0A8I6A8R7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDVDRLCDEHLRAKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQVYDSTDSENDEDGDLSEDSMRSEILDARAQDSVGRSDNEMCELDPGQFIDRARALIREQEMAENKPKREGSNKERDHGPNSLQPEGKHLAETLKQELNTAMSQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGNVQMPSSTDQTEALPLVVRKNSSEQSASGPATGGHHQPLHQSFRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSPAHPPSTAEGLSLSLIKSECGDLQDMSDISPYSGSAISFYLSPQEQVLTKARRRSAQIWFPCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE
Protein: Neuromedin-S (Q5H8A3)
Organism: Homo sapiens (Human)
Function: Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Neuromedin-U receptor 2
- Neuromedin-U receptor 1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Neuropeptide B
- Neuromedin-B
- Gastrin-releasing peptide
- Neuropeptide S
- Neuropeptide W
Sequence:
MKHLRPQFPLILAIYCFCMLQIPSSGFPQPLADPSDGLDIVQLEQLAYCLSQWAPLSRQPKDNQDIYKRFLFHYSRTQEATHPVKTGFPPVHPLMHLAAKLANRRMKRILQRGSGTAAVDFTKKDHTATWGRPFFLFRPRNGRNIEDEAQIQW
Protein: UPF0220 protein C8D2.02c (O43073)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Vacuolar protein sorting-associated protein 55
Sequence:
MTLLDSSIFRFRLSSLHVSSRSLGVYFAGIMFASAVWVFVDAALYSAFDYARNLHITFIDWIPFLCSILGIVIVNSIDKSRLSGDSFAYTDESLARKARFILFIGFALLAGGLGGSFTVFILKYVVAGYEGKSLLMGSANIISNILFMISATALWITGNMNDDYHYNLQL
Protein: DNA 3'-5' helicase (EC 5.6.2.4) (O53348)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- DNA 3'-5' helicase
- ATP-dependent DNA helicase UvrD2
- Putative bifunctional exonuclease/endonuclease protein Rv2191
- Protein RecA
- Replicative DNA helicase DnaB
- DNA polymerase I
- DNA repair protein RadA
- NAD-capped RNA hydrolase NudC
- Possible transmembrane cation transporter
- ATP-dependent DNA helicase UvrD1
Sequence:
MSHIWGVEAGAALAPGLRGPVLVLGGPGTGKSTLLVEAAVAHIGAGTDPESVLLLTGSGRMGMRARSALTTALLRSRTNGPCRAAIREPVVRTVHSYAYAVLRKAAQRAGDALPRLLTSAEQDAIIRELLAGDAEDGPAATTTWPAHLRPALTTAGFATELRNLLARCAERGLDPLELQQLGRRRGRPEWIAAGQFAQRYEQVMLLRGAVGLAAPQATAPALSAAELVGAALEAFAVDPELLAAERARVRTLLVDDAQQLDPQAARLVRMLAAGTELALIAGDPNQAVFGFRGGEPTGLLADDPPPAGGAPIPSVTLTVSHRCAPAVARAVTGIARRLPGRSVGRRIEGTGTEVGSVTVRLAGSAHAEAAMIADALRRAHLIDGVPWSQMAVIVRSVPRAVRLPRALAAAGVPVAPPAVGGPLSAEPAVRALLTVLEATADGLDGDQALLLLTGPIGGVDPVSLRQLRRTLQRARPGQTSRKFGDLLVEVLGGDAPPSGPGSRALRRVRAVLTAAARCHRSGSLGGQDPRHTLWAAWQRSGLQRRWLAASEHGGAAAVQATRDLETVTALFDITDHYVSRTSGASLRGLVEHVTALQLPVVRPEPAAPTEQVMVLSAHAALGHEWDLVVIAGLQDGLWPNTVPRGGVLGTQRLLDELDGVTKDASMRAPLLAEERRLLVTAMGRARRRLLVTAVDSDAGGGGHEAVLPSAFFFEIAQWADGDGEPVAMQPVSAPRVLSAAAVVGRLRVVVCAPACAVDDADRDCAATQLARLAKAGVPGADPSEWHGLAPVSTSDPLCDSDDLVTLTPSTLQALNDCPLRWLAERHGGTNTRELPSAVGSVLHALFAEPGRSESQLLAELDRVWGHLPFGAQWYSANELARHRAMIQAFVQWRAQSRSELTEVGVEVDIDGALEDGSGQARKIRLRGRADRLERDPAGRLVIVDIKTGKTPVSKDDAQQHAQLAMYQLAVAEGLVRAGDEPGGARLVYVGKSGAAGVAERKQDPLTPAARDEWRNLVRQLAAATAGPQFIARRNDGCTHCPLRPGCPAHVRGSAP
Protein: SPI6 (Serine (Or cysteine) peptidase inhibitor, clade B, member 9) (O08797)
Organism: Mus musculus (Mouse)
Interaction partners:
- Cathepsin G
- Albumin
- Thyroglobulin
- T-cell surface glycoprotein CD4
- Interferon gamma
- Interleukin-4
- Granulocyte-macrophage colony-stimulating factor
- Interleukin-5
- Interleukin-13
- NK13
Sequence:
MNTLSEGNGTFAIHLLKMLCQSNPSKNVCYSPASISSALAMVLLGAKGQTAVQISQALGLNKEEGIHQGFQLLLRKLNKPDRKYSLRVANRLFADKTCEVLQTFKESSLHFYDSEMEQLSFAEEAEVSRQHINTWVSKQTEGKIPELLSGGSVDSETRLVLINALYFKGKWHQPFNKEYTMDMPFKINKDEKRPVQMMCREDTYNLAYVKEVQAQVLVMPYEGMELSLVVLLPDEGVDLSKVENNLTFEKLTAWMEADFMKSTDVEVFLPKFKLQEDYDMESLFQRLGVVDVFQEDKADLSGMSPERNLCVSKFVHQSVVEINEEGTEAAAASAIIEFCCASSVPTFCADHPFLFFIRHNKANSILFCGRFSSP
Protein: Dof zinc finger protein DOF2.2 (AtDOF2.2) (Q9ZV33)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- F12P19.8 protein
- Protein BIG GRAIN 1-like A
Sequence:
MVFSSVSSFLDPPINWPQSANPNNHPHHHQLQENGSLVSGHHQVLSHHFPQNPNPNHHHVETAAATTVDPSSLNGQAAERARLAKNSQPPEGALKCPRCDSANTKFCYFNNYNLTQPRHFCKACRRYWTRGGALRNVPVGGGCRRNKKGKSGNSKSSSSSQNKQSTSMVNATSPTNTSNVQLQTNSQFPFLPTLQNLTQLGGIGLNLAAINGNNGGNGNTSSSFLNDLGFFHGGNTSGPVMGNNNENNLMTSLGSSSHFALFDRTMGLYNFPNEVNMGLSSIGATRVSQTAQVKMEDNHLGNISRPVSGLTSPGNQSNQYWTGQGLPGSSSNDHHHQHLM
Protein: Heme-binding protein 2 (Protein SOUL) (Q9WU63)
Organism: Mus musculus (Mouse)
Function: Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions (By similarity). May have low affinity for heme.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9Y5Z4}. Mitochondrion {ECO:0000250|UniProtKB:Q9Y5Z4}. Note=Mainly localized to the cytoplasm with a much lower abundance in the mitochondrion. {ECO:0000250|UniProtKB:Q9Y5Z4}.
Interaction partners:
- Bcl-2-like protein 1
- Chromatin remodeling regulator CECR2
Sequence:
MAEEPEPDLGVAEGSEDQALEMPSWKAPEDIDPQPGSYEIRHYGPAKWVSTCVESLDWDSAIQTGFTKLNGYIQGKNEKEMKIKLTAPVTSYVEPGSSPFSESTITISLYIPSEQQPDPPRPSESDVFIEDRAEMTVFVRSFDGFSSGQKNQEQLLTLANILREEGKVFNEKVFYTAGYSSPFQLLDRNNEVWLIQKNEPSVENK