wanglab/gogpt-training-data huggingface dataset:
Protein: GRF1-interacting factor 1 (AtGIF1) (Protein ANGUSTIFOLIA 3) (Transcription coactivator GIF1) (Q8L8A5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription coactivator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. Appears to function synergistically with GRF1 as a transcriptional coactivator. Acts together with GRF5 for the development of appropriate leaf size and shape through the promotion and/or maintenance of cell proliferation activity in leaf primordia. Plays a role in adaxial/abaxial patterning and growth in leaf morphogenesis. GIFs are involved in the positive regulation of cell proliferation of lateral organs in a functionally redundant manner. Together with GATA18/HAN, mediates cotyledon identity by preventing ectopic root formation through the repression of PLT1 expression.
Interaction partners:
- Growth-regulating factor 5
- Growth-regulating factor 1
- Growth-regulating factor 9
- Growth-regulating factor 4
- Growth-regulating factor 2
- Growth-regulating factor 3
- Transcription factor TCP4
- Growth-regulating factor 6
- Cytochrome P450 78A5
- SWI/SNF complex subunit SWI3C
Sequence:
MQQHLMQMQPMMAGYYPSNVTSDHIQQYLDENKSLILKIVESQNSGKLSECAENQARLQRNLMYLAAIADSQPQPPSVHSQYGSAGGGMIQGEGGSHYLQQQQATQQQQMTQQSLMAARSSMLYAQQQQQQQPYATLQHQQLHHSQLGMSSSSGGGGSSGLHILQGEAGGFHDFGRGKPEMGSGGGGEGRGGSSGDGGETLYLKSSDDGN
Protein: Tubulo-interstitial nephritis antigen (Tubulointerstitial nephritis antigen) (Q9WUR0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MWTGYKILIFFSLTTDICTETHFSQGEAEPGPRFTRNHTIFEGSRHKRAIFQGEYCRRFGCCEARDDTCVTQFYEANALCYCDSFCERDTSDCCPDYKSFCHEEKEEPPFQQPSDPEGCFRDSQHYEEGSVVKENCNSCTCSGQQWKCSQHVCLVHPELIDHINKGDYGWTAQNYSQFWGMTLEEGFKFRLGTLPPSPMLLSMNEMTASFPPRADLPEIFIASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWFLRKRGLVSHACYPLFKDQNTTNNICAMASRSDGRGKRHATKPCPNSFEKSNRIYQCSPPYRVSSNETEIMREIIQNGPVQAIMQVHEDFFYYKTGIYRHVVSTNEEPEKYKKLRTHAVKLTGWGTLRGARGKKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDDP
Protein: Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 (Serine/threonine-protein phosphatase 2A 56kDa regulatory subunit pptr-1) (Serine/threonine-protein phosphatase 2A regulatory subunit B' pptr-1) (O18178)
Organism: Caenorhabditis elegans
Function: Probable regulatory subunit of serine/threonine-protein phosphatase let-92 which negatively regulates the insulin receptor signaling cascade composed of daf-2, age-1, akt-1, akt-2 and sgk-1 by promoting the dephosphorylation of akt-1 on 'Thr-350'. Negatively regulates several functions controlled by the insulin pathway including dauer formation, lifespan, fat storage and stress resistance. Plays a role in the asymmetric segregation of the P granule components during embryonic cell divisions but does not play an essential role in specifying germ cell fate. Within a PP2A phosphatase complex, acts redundantly with pptr-2, to dephosphorylate P granule components including meg-1 and meg-3 to promote the assembly and accumulation of zygotic P granules in the posterior cytoplasm during zygote polarization, and thus maintain P granule distribution and segregation in early stage embryos following meiosis. In adults, required to promote germ cell proliferation and differentiation when exposed to thermic stress.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19249087}.
Interaction partners:
- Probable serine/threonine-protein phosphatase PP2A regulatory subunit
- Serine/threonine-protein phosphatase 2A catalytic subunit
- Serine/threonine-protein phosphatase 2A regulatory subunit sur-6
- Serine/threonine-protein phosphatase 2A regulatory subunit rsa-1
- Serine/threonine protein phosphatase 2A regulatory subunit
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- Uncharacterized protein
- Serine/threonine-protein kinase akt-2
- J domain-containing protein
Sequence:
MHGSGHSLTGAPHQIPPPRTQGAATGGQQLSATANQFVDKIDPFHNKRGTSRRLRINNSSRYNVDSAQELVQLALIKDTAANEQPALVIEKLVQCQHVFDFYDPVAQLKCKEIKRAALNELIDHITSTKGAIVETIYPAVIKMVAKNIFRVLPPSENCEFDPEEDEPTLEVSWPHLQLVYELFLRFLESPDFQASIGKKYIDQRFVLKLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKHINNMFLRFVYETDSFNGVGELLEILGSIINGFALPLKQEHKVFLVKVLLPLHKPKCLSLYHAQLAYCVVQFIEKDSSLTPQVFEALLKFWPRTCSSKEVMFLGEVEEILDIIEPEQFKKIIDPLFRQLAKCVSSPHFQVAERALYFWNNEYILSLIEDTSSLVMPIMFPALYRISKEHWNQTIVALVYNVLKTFMEMNGKLFDELTSTYKGERLREKQREKDRDAFWKKMEALELNPPAEGKEVTPSLFPEKLTDYLKKDGPNMTPLPVATAGGGDKSPSVVKKSSTGSETTTPAKK
Protein: Flagellar motor switch protein FliN (Q57259)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Function: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
Subcellular location: Cell inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Bacterial flagellum basal body {ECO:0000250}.
Interaction partners:
- Flagellar motor switch protein FliM
- Flagellar motor switch protein FliG
- Flagellar basal-body rod protein FlgC
- Flagellum-specific ATP synthase
- Flagellar biosynthetic protein
- Basal-body rod modification protein FlgD
- Flagellar hook protein FlgE
- Flagellar L-ring protein
- Flagellar basal-body rod protein FlgG
- Flagellar M-ring protein
Sequence:
MATKKTPVTDDAALPSFEDGVDLDQAIGDLRGVLKTDAEGSLSDFGDFGDFGSTDEVSTDNDLSAFGGGAADFAMDDFAAAPQVAGVKAPLGSGLSENMEMIMDIPIDVQIVLGTSRMLVSGLMSLEEGATIALDRKIGEPVEIMVNGRRIARGEITVLEDDDTRFGVKLIEVLSTRKA
Protein: Prepronociceptin [Cleaved into: Nocistatin; Nociceptin (ORL1 receptor agonist) (Orphanin FQ) (PPNOC); Orphanin FQ2] (Q62923)
Organism: Rattus norvegicus (Rat)
Function: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.
Subcellular location: Secreted.
Interaction partners:
- Nociceptin receptor
- Proenkephalin-B
- Pro-opiomelanocortin
- Corticoliberin
- Mu-type opioid receptor
- Galanin peptides
- Protachykinin-1
- Kappa-type opioid receptor
- Hypocretin neuropeptide precursor
- Pro-neuropeptide Y
Sequence:
MKILFCDVLLLSLLSSVFSSCPEDCLTCQERLHPAPGSFNLKLCILQCEEKVFPRPLWTLCTKAMASDSEQLSPADPELTSAALYQSKASEMQHLKRMPRVRSVVQARDAEPEADAEPVADEADEVEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNV
Protein: Complex I assembly factor ACAD9, mitochondrial (Acyl-CoA dehydrogenase family member 9) (ACAD-9) (EC 1.3.8.-) (Q8JZN5)
Organism: Mus musculus (Mouse)
Function: As part of the MCIA complex, primarily participates in the assembly of the mitochondrial complex I and therefore plays a role in oxidative phosphorylation. This moonlighting protein has also a dehydrogenase activity toward a broad range of substrates with greater specificity for long-chain unsaturated acyl-CoAs. However, in vivo, it does not seem to play a primary role in fatty acid oxidation. In addition, the function in complex I assembly is independent of the dehydrogenase activity of the protein.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9H845}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9H845}; Matrix side {ECO:0000250|UniProtKB:Q9H845}. Note=Essentially associated with membranes. {ECO:0000250|UniProtKB:Q9H845}.
Interaction partners:
- Complex I intermediate-associated protein 30, mitochondrial
- Complex I assembly factor TMEM126B, mitochondrial
- Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
- Complex I assembly factor TIMMDC1, mitochondrial
- NADH-ubiquinone oxidoreductase chain 6
- NADH dehydrogenase 1 alpha subcomplex assembly factor 3
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
Sequence:
MSGCVLLSRGATAAAAAARASRVLREFTARRRPLHTSLQSCSFAKELFLGNIEQKGVFPFPEVSQHELSEINQFVGPLEKFFTEEVDSRKIDQEGKIPVDTLEKLKSLGLFGIQVPEEYGGLGLSNTMYARLGEIISLDASITVTLAAHQAIGLKGIILVGNEEQKAKYLPKLSSGEHIAAFCLTEPASGSDAASIQTRATLSEDKKYFILNGSKVWITNGGLANIFTVFAKTEVVDSDGSKTDKMTAFIVERDFGGITNGKPEDKLGIRGSNTCEVHFENTRVPVENVLGEVGGGFKVAMNILNSGRFSMGSAVAGMLKKLIELTAEYACTRKQFNRNLSEFGLIQEKFALMAQKAYVMESMAYLTSGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGSGYMKDYPYERMLRDARILLIFEGTNEILRLFIALTGLQHAGRILTSRIKELKSGNVTTVMETIGRKLRDSLGRTVDLGLTGDLGVVHPSLGDSANKLEENVHYFGRTVETLLLRFGKNIVEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANMFCVEAYFQNLFSLSQLDKNAPENLDEQIKKVSRQILEKRAYICAHPLDRAS
Protein: histidine kinase (EC 2.7.13.3) (Q1D0A1)
Organism: Myxococcus xanthus (strain DK1622)
Interaction partners:
- Pilin regulatory protein PilR
- RNA polymerase sigma-54 factor
- Type IV pilus assembly protein PilC
- Response regulator
- Twitching motility protein PilT
- Response regulator/chemotaxis protein CheW
- DNA-binding response regulator
- Response regulator
- Response regulator
- PilG
Sequence:
MRPSERGAFRSRLVWLVLFRTVAASLSLVITLARLLLHPSQELNHADTLSLAVIIIAYVSTVVVGLRLRKGQGGLGDAWVQVVGDVVIATGLVYLSGGSDSPLTFLYSLAVIGASVVLDRRGALWAAAASALCFGALVMGSQLLDGASGGLMPPTRVLFVLGSNSLALGLIAVLSGYLSRQLSATGGALSAREADLQRLGRLQQQILSSMPSGLATCDAQRRVTYVNPAGCGILQVDPTQVAGVEVEALLPGVSVLAPRSPRSELVVGKGAKRRILGLSVTPLEGEPGALLMVFQDLTQLRRMEDDLKRADRLASLGALSAQLAHELRNPLASMRGSAQLLAQDARDDVAQKLTNILMRESDRLARLVEEFLRFARPPVPSLRRVPLASLVTETMDMLRVDPLARDVRVEVTAPEPLPVSVDPDQLRQVLINLVRNGFLAAGPRGEVKVALTRSENEARIRIWDSGGSITEEMMGHLFEPFFTTRDGGTGLGLSTAHSIIRAHGGSIRVRSNRDEGTEFVVGLPL
Protein: Heterogeneous nuclear ribonucleoprotein A/B (F7F9P3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSDAAEEQPMETTGATENGHEAAPEGEAPVEPSPGAAAPATPAGSGGGTTAAPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDSSSVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGQFGEIEAIELPIDPKLNKRRGFVFITFKEEDPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSK
Protein: Cadmium, zinc and cobalt-transporting ATPase (EC 7.2.2.12) (EC 7.2.2.21) (Q59465)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Couples the hydrolysis of ATP with the transport of cadmium, zinc and cobalt out of the cell. This ion efflux may influence the activity of urease, which is essential for the survival of the bacterium in the gastric environment.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- COP-associated protein
- Sigma-54 interacting protein
- Peptide deformylase
- ATP-dependent Clp protease proteolytic subunit
- Trigger factor
Sequence:
MQEYHIHNLDCPDCASKLERDLNELDYVKKAQINFSTSKLFLDTSDFEKVKAFIKQNEPHLSLSFKEATEKPLSFTPLIITIMVFLGAILILHLNPSPLIEKAMFFVLALVYLVSGKDVILGAFRGLRKGQFFDENALMLIATIAAFFVGAYEESVSIMVFYSAGEFLQKLAVSRSKKSLKALVDVAPNLAYLKKGDELVSVAPEDLRVNDIVVVKVGEKVPVDGVVVKGESLLDERALSGESMPVNVSENSKVLGGSLNLKAVLEIQVEKMYKDSSIAKVVDLVQQATNEKSETEKFITKFSRYYTPSVLFIALMIAVLPPLFSMGSFDEWIYRGLVALMVSCPCALVISVPLGYFGGVGAASRKGILMKGVHVLEVLTQAKSIAFDKTGTLTKGVFKVTDIVPQNGHSKEEVLHYASCSQLLSTHPIALSIQKACEEMLKDDKHQHDIKNYEEVSGMGVKAQCHTDLIIAGNEKMLDQFHIAHSPSKENGTIVHVAFNQTYVGYIVISDEIKDDAIECLRDLKVQGIENFCILSGDRKSATESIAQTLGCEYHASLLPEEKTSVFKTFKERYKAPAIFVGDGINDAPTLASADVGIGMGKGSELSKQSADIVITNDSLNSLVKVLAIAKKTKSIIWQNILFALGIKAVFIVLGLMGVASLWEAVFGDVGVTLLALANSMRAMRA
Protein: BBG-LP43 (Q15K30)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
SISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA
Protein: E3 ubiquitin ligase complex SCF subunit (F2Z631)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome J complete sequence
- Candida glabrata strain CBS138 chromosome L complete sequence
- Candida glabrata strain CBS138 chromosome E complete sequence
- Candida glabrata strain CBS138 chromosome M complete sequence
- Candida glabrata strain CBS138 chromosome J complete sequence
- Candida glabrata strain CBS138 chromosome L complete sequence
- Candida glabrata strain CBS138 chromosome M complete sequence
- Candida glabrata strain CBS138 chromosome F complete sequence
- Protein phosphatase PP2A regulatory subunit B
- Candida glabrata strain CBS138 chromosome H complete sequence
Sequence:
MDKKGKYVVLVSGEGEKFTVEKKIAQRSLLLKNYLNDMHESSLDDEDEEQDEDEDEDDEIVMPVPNVRSSVLQKVIEWAEHHRDSNFPDEDDDDSRKSAPVDAWDREFLKVDQEMLYEIILAANYLNIKPLLDAGCKVVAEMIRGRSPEEIRRTFNIVNDFTPEEEAAIRRENEWAEDR
Protein: Alanine racemase, catabolic (EC 5.1.1.1) (O59828)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Putative alanine racemase 2
- D-amino-acid oxidase
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Sequence:
MRGAKSVIDLHAIAHNYNVAKQMMLQKNPSGHVLAIVKANAYGHGAVQVARFLLKHCSSIDGFGVSSIEEALELRHGGIYNKIVLLEGFFTEEDELKLIDDYNFSIIIHSEDQVNSFIKYPFNRPVEIWLKLDSGMNRLGFTPSQFMKFYNLLSNNKNVSNIGKITHFAFADMLENPEHTLKQWDIFEKSVAHLPGPLSAGGSAIILGWLNTVCTDWLRAGIMLYGISPFLSKNKDSKTPESVNIKPAMKLVSTIISVKHVDKGQPIGYGGRYVATRDMKLGVVAMGYGDGFPRQVKDGCPVLVNGVKAPIVGRVSMDMLTVDLSDIPDVKPGDEVIFWGTPELTVADIAKYCSDTSPYELVTKLTRRVPLQYTY
Protein: RNA-binding motif protein 4.2 (RNA-binding protein 4.2 isoform X1) (F1Q7F8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- plus-end-directed kinesin ATPase
Sequence:
MVKIFIGNLSPTSTADDLRSLFSEFGIVKECDVLKNYGFVHMDSKKEAEAAIRKLHHYELKGQAINVELSKGKPRGSTKLHVSNISSGCTNQELRAKFEEYGPVVECDIVKDYAFVHMERMDDAMEAISGLENTTFQGKLIKVQLSTSRLRTAPGMGDQTGCYICGEQGHWSKDCRHSQNGSYGGGMGGYPSRGPPRGGPSYGMGGPGGHPSRGYPAGPLPPPPPMSRRPSYGEYGAEPRERYLTRVPTGYPERPPVYERDRFGSIDYYEKFRAHPAASSYYEDRPHAIPPPPPPPPLSSSSLSRMRLAPPSLDPYERRSLAPPPPTAAAASFARDRSPIRRVGAGAEGYSYERSRLSPVSRSSSAYSLPRAREGYTERVRYAY
Protein: Uncharacterized PPE family protein PPE54 (Q6MWY2)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Probably plays a role in host phagosome maturation arrest.
Interaction partners:
- PE-PGRS family protein PE_PGRS16
- Outer membrane channel protein CpnT
- CRISPR system Cms protein Csm5
- Uncharacterized protein Rv2209
- ESX-1 secretion-associated protein EspK
- Uncharacterized protein Rv2082
- Isoniazid-induced protein IniB
- PE-PGRS family protein PE_PGRS43
- PE-PGRS family protein PE_PGRS2
- PE-PGRS family protein PE_PGRS15
Sequence:
MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGPSSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAETVDPFVIAANRSRLVSLALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAEPAKSLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGEANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGVLWRGDYQGLLGFSSGANVLPVIPLSLDINGGVGAITIEPIHILPDIPININETLYLGPLVVPPINVPAISLGVGIPNISIGPIKINPITLWPAQNFNQTITLAWPVSSITIPQIQQVALSPSPIPTTLIGPIHINTGFSIPVTFSYSTPALTLFPVGLSIPTGGPLTLTLGVTAGTEAFTIPGFSIPEQPLPLAINVIGHINALSTPAITIDNIPLNLHAIGGVGPVDIVGGNVPASPGFGNSTTAPSSGFFNTGAGGVSGFGNVGAHTSGWFNQSTQAMQVLPGTVSGYFNSGTLMSGIGNVGTQLSGMLSGGALGGNNFGLGNIGFDNVGFGNAGSSNFGLANMGIGNIGLANTGNGNIGIGLSGDNLTGFGGFNSGSENVGLFNSGTGNVGFFNSGTGNLGVFNSGSHNTGFFLTGNNINVLAPFTPGTLFTISEIPIDLQVIGGIGPIHVQPIDIPAFDIQITGGFIGIREFTLPEITIPAIPIHVTGTVGLEGFHVNPAFVLFGQTAMAEITADPVVLPDPFITIDHYGPPLGPPGAKFPSGSFYLSISDLQINGPIIGSYGGPGTIPGPFGATFNLSTSSLALFPAGLTVPDQTPVTVNLTGGLDSITLFPGGLAFPENPVVSLTNFSVGTGGFTVFPQGFTVDRIPVDLHTTLSIGPFPFRWDYIPPTPANGPIPAVPGGFGLTSGLFPFHFTLNGGIGPISIPTTTVVDALNPLLTVTGNLEVGPFTVPDIPIPAINFGLDGNVNVSFNAPATTLLSGLGITGSIDISGIQITNIQTQPAQLFMSVGQTLFLFDFRDGIELNPIVIPGSSIPITMAGLSIPLPTVSESIPLNFSFGSPASTVKSMILHEILPIDVSINLEDAVFIPATVLPAIPLNVDVTIPVGPINIPIITEPGSGNSTTTTSDPFSGLAVPGLGVGLLGLFDGSIANNLISGFNSAVGIVGPNVGLSNLGGGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGFGNVGLANSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYRPAVLPQTPFLDLTLTGGLGSVVIPAIDIPAIRPEFSANVAIDSFTVPSIPIPQIDLAATTVSVGLGPITVPHLDIPRVPVTLNYLFGSQPGGPLKIGPITGLFNTPIGLTPLALSQIVIGASSSQGTITAFLANLPFSTPVVTIDEIPLLASITGHSEPVDIFPGGLTIPAMNPLSINLSGGTGAVTIPAITIGEIPFDLVAHSTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVANIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPVFDLGPITVQDITIPALGLDPATGVTVGPIFSSGSIIDPFSLTLLGFINVNVPAIQTAPSEILPFTVLLSSLGVTHLTPEITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRIPVVLDVNALLGPINAGLVIPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGFGNVGQQLAGLIYTGTGP
Protein: Germ cell-specific gene 1-like protein (GSG1-like protein) (D3Z7H4)
Organism: Mus musculus (Mouse)
Function: As a component of the inner core of AMPAR complexes, modifies AMPA receptor (AMPAR) gating.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22632720}; Multi-pass membrane protein {ECO:0000269|PubMed:22632720}. Synapse {ECO:0000250}.
Interaction partners:
- Protein shisa-9
- Protein cornichon homolog 2
- Protein cornichon homolog 1
- Synapse differentiation-inducing gene protein 1
- Protein cornichon homolog 3
- Voltage-dependent calcium channel gamma-8 subunit
Sequence:
MKTSRRGRALLAVALNLLALLFATTAFLTTYWCQGTQRVPKPGCGQGGGANCPNSGANATANSTAAPVAASPAGAPYSWEAGDERFQLRRFHTGIWYSCEEELGGPGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELVHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPEAIKYFRERIEKGDVSEEEDFRLACRHERYPTRHQPHMGDSWPRSSAHEAAELNRQCWVLGHWV
Protein: Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (O44512)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion inner membrane {ECO:0000256|RuleBase:RU004495}.
Interaction partners:
- Probable NADH dehydrogenase 1 alpha subcomplex subunit 12
- Cytochrome c oxidase subunit 6A, mitochondrial
- Probable NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- Cytochrome c oxidase subunit 4
- Cytochrome c oxidase subunit 5A, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3
- Cytochrome c oxidase subunit 1
- Cytochrome b
- Probable NADH dehydrogenase iron-sulfur protein 8, mitochondrial
Sequence:
MASLARSGGFAVKVISGSQQHVNFVAATPAADNVAAFRDVPAEFSTAEARQAAVSHSTGGVFTNGLAVKGINVTSRRLAHTDVTFPDMSNYRRDSTKNTQVPARDTEDQRRALPTALYYGAGGVLSLWAGKEVVQTLVSYKAMAADQRALASIEINMADIPEGKTKTFEWRGKPVFVKHRTKAEIAKEKAVPVADLRHPQHDDERVQKDEWSVVIGVCTHLGCVPIADAGDYGGYYCPCHGSHYDASGRIRKGPAPLNLHVPAYSFKDATIVIGSS
Protein: Polyketide cyclase / dehydrase and lipid transport protein (Q9M120)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MQSSPILLDFSSAFHHPRAAALATTSGLTNSHSPTKKYRLITSFSPSSTLLASSRRCFTCRFGDSSPRFNSNEDETETETDDEDDYCLTDGKTEELVVGDDGVLIELKKLEKSSRRIRSKIGMEASLDSVWSVLTDYEKLSDFIPGLVVSELVEKEGNRVRLFQMGQQNLALGLKFNAKAVLDCYEKELEVLPHGRRREIDFKMVEGDFQLFEGKWSIEQLDKGIHGEALDLQFKDFRTTLAYTVDVKPKMWLPVRLVEGRLCKEIRTNLMSIRDAAQKVIEGVIHDL
Protein: Cyclin-D3-2 (G1/S-specific cyclin-D3-2) (CycD3;2) (Q9FGQ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes divisions in the guard cells (GCs) after the guard mother cells (GMC) symmetric division when in the presence of CDKA-1.
Interaction partners:
- Retinoblastoma-related protein 1
- Cyclin-dependent kinase A-1
- Cyclin-D3-3
- Cyclin-D3-1
- Cyclin-dependent kinases regulatory subunit 1
- Cyclin-dependent kinase B1-1
- Cyclin-dependent kinase B2-1
- Cyclin-dependent kinases regulatory subunit 2
- Cyclin-dependent kinase B1-2
- Cyclin-U4-1
Sequence:
MALEKEEEASQNGAFCVLDGLYCEEETGFVEDDLDDDGDLDFLEKSDESVVKFQFLPLLDMFLWDDDEILSLISKENETNPCFGEQILDGFLVSCRKEALDWVLRVKSHYGFTSLTAILAVNYFDRFMTSIKLQTDKPWMSQLVAVASLSLAAKVEEIQVPLLLDLQVEEARYLFEAKTIQRMELLILSTLQWRMHPVTPISFFDHIIRRFGSKWHQQLDFCRKCERLLISVIADTRFMRYFPSVLATAIMILVFEELKPCDEVEYQSQITTLLKVNQEKVNECYELLLEHNPSKKRMMNLVDQDSPSGVLDFDDSSNSSWNVSTTASVSSSSSSPEPLLKRRRVQEQQMRLPSINRMFLDVLSSPR
Protein: Semaphorin-3F (Sema III/F) (Semaphorin IV) (Sema IV) (Q13275)
Organism: Homo sapiens (Human)
Function: May play a role in cell motility and cell adhesion.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Neuropilin-1
- Neuropilin-2
- Plexin-A3
- Plexin-A1
- Plexin-A4
- Neuronal cell adhesion molecule
- Plexin-D1
Sequence:
MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQDYIFYLEPERLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQSPAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSKRRSRRQDVRHGNPIRQCRGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPGDRRREIRAEDRFLRTEQGLLLRALQLSDRGLYSCTATENNFKHVVTRVQLHVLGRDAVHAALFPPLSMSAPPPPGAGPPTPPYQELAQLLAQPEVGLIHQYCQGYWRHVPPSPREAPGAPRSPEPQDQKKPRNRRHHPPDT
Protein: GH24215p (Q8T0L4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQVC
Protein: Protein kinase, putative (Q38E60)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQKYAILGKKGEGTFSEVLKAQDVETKAYVAIKCMRKPFQSKEQVNRLREIQAVRRLQPHPNIVPLIEVMFDKTTGRLALVFELMDMNLYEFIRGRRHQLDEHCVMTLMYQLFKALDHAHRKGIFHRDIKPENILLREDGTLKLADFGSCRGLHVSQPLTEYVSTRWYRAPECLLTSGYYTHKMDLWAAGCVFFEIIALTPLFPGTTEMDQIHKIHDVLGTPPVDVLNTLKKFGAPINFQFSEKKGTGVARLLPEGTSKEAIDLIGRLLQYDEKERVTAKEALRHPYFKPLRGKERQERHRAMEYSTEKAKTLEVDSVLPCLTRVVVSKRGPMTTENRPHVRLEDLSNANGRISAQSVLPKLQG
Protein: F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (Q5BJ29)
Organism: Mus musculus (Mouse)
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. During mitosis, it mediates the ubiquitination and subsequent proteasomal degradation of AURKA, causing mitotic arrest. It also regulates mitochondrial function by mediating the ubiquitination and proteasomal degradation of the apoptosis inhibitor BIRC5.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22306998}. Note=Localizes to the centrosome during spindle formation. {ECO:0000269|PubMed:22306998}.
Interaction partners:
- S-phase kinase-associated protein 1
- Cullin-1
- E3 ubiquitin-protein ligase RBX1
- Aurora kinase A
Sequence:
MGANNGKQYGSEGKGSSSVSSDVSSSTDHTPTKAQRNVATSEDSDLSMRTLSTPSPALICPPTLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRITDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF