wanglab/gogpt-training-data huggingface dataset:
Protein: ADP-ribosylation factor 1 (EC 3.6.5.2) (O00909)
Organism: Dictyostelium discoideum (Social amoeba)
Function: GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Subcellular location: Golgi apparatus {ECO:0000250}.
Interaction partners:
- Coatomer subunit gamma
- Ras guanine nucleotide exchange factor S
- Coatomer subunit beta
- Phosphatidylinositol 4-kinase
- Rac guanine nucleotide exchange factor B
- Uncharacterized protein
Sequence:
MGLAFGKLFSRFFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEFKNINFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEACDELTKMLNEDELRDAVLLVFCNKQDLPNAMSVAEVTDKLNLHSLRSRKWYIQSTCATSGDGLYEGLDWLSNTLTSSSK
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (B3KX59)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHRKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW
Protein: Leukosialin (Leukocyte sialoglycoprotein) (Sialophorin) (W3/13 antigen) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)] (P13838)
Organism: Rattus norvegicus (Rat)
Function: Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment. Promotes the expression of IFN-gamma by T-cells during T-cell receptor (TCR) activation of naive cells and induces the expression of IFN-gamma by CD4(+) T-cells and to a lesser extent by CD8(+) T-cells. Plays a role in preparing T-cells for cytokine sensing and differentiation into effector cells by inducing the expression of cytokine receptors IFNGR and IL4R, promoting IFNGR and IL4R signaling and by mediating the clustering of IFNGR with TCR. Acts as a major E-selectin ligand responsible for Th17 cell rolling on activated vasculature and recruitment during inflammation. Mediates Th17 cells, but not Th1 cells, adhesion to E-selectin. Acts as a T-cell counter-receptor for SIGLEC1.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. Cell projection, microvillus {ECO:0000269|PubMed:9472040}. Cell projection, uropodium {ECO:0000250|UniProtKB:P15702}. Note=Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN). {ECO:0000250|UniProtKB:P15702, ECO:0000269|PubMed:9472040}.; SUBCELLULAR LOCATION: [CD43 cytoplasmic tail]: Nucleus {ECO:0000250|UniProtKB:P15702}. Nucleus, PML body {ECO:0000250|UniProtKB:P15702}. Note=The sumoylated form localizes to the PML body. {ECO:0000250|UniProtKB:P15702}.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase C
- E-selectin
- Radixin
- CD19 molecule
- Ezrin
- Sialophorin like 1
- Moesin
- Intercellular adhesion molecule 1
- L-selectin
- T-cell surface glycoprotein CD5
Sequence:
WAQVVSQENLPNTMTMLPFTPNSESPSTSEALSTYSSIATVPVTEDPKESISPWGQTTAPASSIPLGTPELSSFFFTSAGASGNTPVPELTTSQEVSTEASLVLFPKSSGVASDPPVTITNPATSSAVASTSLETFKGTSAPPVTVTSSTMTSGPFVATTVSSETSGPPVTMATGSLGPSKETHGLSATIATSSGESSSVAGGTPVFSTKISTTSTPNPITTVPPRPGSSGMLLVSMLIALTVVLVLVALLLLWRQRQKRRTGALTLSRGGKRNGTVDAWAGPARVPDEEATTASGSGGNKSSGAPETDGSGQRPTLTTFFSRRKSRQGSVALEELKPGTGPNLKGEEEPLVGSEDEAVETPTSDGPQAKDGAAPQSL
Protein: Yop proteins translocation protein O (P40294)
Organism: Yersinia pseudotuberculosis serotype I (strain IP32953)
Function: Component of the yop secretion machinery.
Interaction partners:
Sequence:
MIRRLHRVKVLRVERAEKAIKTQQACLQAAHRRHQEAVQTSQDYHLWRIDEEQRLFDQRKNTTLNCKDLEKWQRQIASLREKEANYELECAKLLERLANERERLTLCQKMLQQARHKENKFLELVRREDEDELNQQHYQEEQEQEEFLQHHRNA
Protein: AT13908p (Q86NT8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
RFLKLQKEIRTTCRDLAMGIKGIIVMTPDLENVMTAMKFNRIPTKWMSKSYPCLKPLGSYVQDLYKRLNWLHDWHHHGKPPTFWLSGFFFTQAFLTGAMQNFARKYKIPIDTLTFDYDVLKVETKTSPPDDGVYCNGLYLEGARWEWRENTLVEQFPKVLIYAMPVIFFRPVGLVDVVEGSRYRCPLYKTAERKGTLSTTGHSTNYVVPLLLNTHVKASHWVKRSVALICQTSD
Protein: Burkholderia TALE-like protein 2 (Modular DNA-binding domain protein BurrH2) (E5AW45)
Organism: Mycetohabitans rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454) (Paraburkholderia rhizoxinica)
Function: Binds to DNA in a sequence-specific manner.
Interaction partners:
Sequence:
MPATSMHQEDKQSANGLNLSPLERIKIEKHYGGGATLAFISNQHDELAQVLSRADILKIASYDCAAQALQAVLDCGPMLGKRGFSRADIVRIAGNGGGAQALYSVLDVEPTLGKRGFSQVDVVKIAGGGAQALHTVLEIGPTLGERGFSRGDIVTIAGNNGGAQALQAVLELEPTLRERGFNQADIVKIAGNGGGAQALQAVLDVEPALGKRGFSRVDIAKIAGGGAQALQAVLGLEPTLRKRGFHPTDIIKIAGNNGGAQALQAVLDLELMLRERGFSQADIVKMASNIGGAQALQAVLNLEPALCERGFSQPDIVKMAGNSGGAQALQAVLDLELAFRERGFSQADIVKMASNIGGAQALQAVLELEPALHERGFSQANIVKMAGNSGGAQALQAVLDLELVFRERGFSQPEIVEMAGNIGGAQALHTVLDLELAFRERGVRQADIVKIVGNNGGAQALQAVFELEPTLRERGFNQATIVKIAANGGGAQALYSVLDVEPTLDKRGFSRVDIVKIAGGGAQALHTAFELEPTLRKRGFNPTDIVKIAGNKGGAQALQAVLELEPALRERGFNQATIVKMAGNAGGAQALYSVLDVEPALRERGFSQPEIVKIAGNIGGAQALHTVLELEPTLHKRGFNPTDIVKIAGNSGGAQALQAVLELEPAFRERGFGQPDIVKMASNIGGAQALQAVLELEPALRERGFSQPDIVEMAGNIGGAQALQAVLELEPAFRERGFSQSDIVKIAGNIGGAQALQAVLELEPTLRESDFRQADIVNIAGNDGSTQALKAVIEHGPRLRQRGFNRASIVKIAGNSGGAQALQAVLKHGPTLDERGFNLTNIVKIAGNGGGAQALKAVIEHGPTLQQRGFNLTDIVEMAGKGGGAQALKAVLEHGPTLRQRGFNLIDIVEMASNTGGAQALKTVLEHGPTLRQRDLSLIDIVEIASNGGAQALKAVLKYGPVLMQAGRSNEEIVHVAARRGGAGRIRKMVALLLERQ
Protein: Poly (ADP-ribose) polymerase family, member 6 (A0A8I6GLB1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILYMFTSQQWKHLSNDLLKTQQEKRHSWFKASGSIRKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQIMKYAEQRVPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLQLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFQ
Protein: Translation initiation factor eIF2B subunit epsilon (eIF2B GDP-GTP exchange factor subunit epsilon) (Q9W541)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
- Eukaryotic translation initiation factor 2 subunit 1
- Translation initiation factor eIF2B subunit gamma
- Translation initiation factor eIF2B subunit beta
- Translation initiation factor eIF2B subunit alpha
- Translation initiation factor eIF2B subunit delta
- Eukaryotic translation initiation factor 2 subunit 3
- Eukaryotic translation initiation factor 2 subunit 2
- Eukaryotic translation initiation factor 5
- non-specific serine/threonine protein kinase
- Guanine nucleotide exchange factor MSS4 homolog
Sequence:
MAQFEKEIVQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLYRSSIREHIRAGIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGADTVTNADLRPVLEQHKRQAKFDKGTAATLVFKECANNVRTGNEVLIAVDRRNDRLHYHQRLRMHHKENRYQLPLDVFLGNSCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQTRDDFVRGLLINEELLDSRIYVALLPAAQYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGLYKLQQEYVFHKDNIYKSPEAHVSKVALLQNVVIEAGSHVDSGSVISDSVIGANCRIGKNCRLTNAFLMADVTVMDNCRLEHCVVGEGAIINEDCDVSAGCVLGAKSVLPAKKTLAKTLITRTPSRRRSDDEVVVELKSIGPHAYIVSDLTTGDPEDSECEDLLPQQPLSIPKMGDLLAPLDEISYCSDFSEDDEDASRAVTPLPDDTNIFLGEVIDSLTRGFREKSNPDFLVLEINSSRYAYNMSLKEVNFNVVKAVFGMQSIVEPANDNVLVAINAAFKQLGPVVSNYIKSEDSMMDCLKALEDVYEENHLVRGKISQIVHYLYDKDFVSESAIQAWYAQLDEEEHAHLRQSLAKLVAWLDQSSEEDDDEEDDD
Protein: Tubulin BtubB (Q8GCC1)
Organism: Prosthecobacter dejongeii
Interaction partners:
Sequence:
VREILSIHVGQCGNQIADSFWRLALREHGLTEAGTLKEGSNAAANSNMEVFFHKVRDGKYVPRAVLVDLEPGVIARIEGGDMSQLFDESSIVRKIPGAANNWARGYNVEGEKVIDQIMNVIDSAVEKTKGLQGFLMTHSIGGGSGSGLGSLILERLRQAYPKKRIFTFSVVPSPLISDSAVEPYNAILTLQRILDNADGAVLLDNEALFRIAKAKLNRSPNYMDLNNIIALIVSSVTASLRFPGKLNTDLSEFVTNLVPFPGNHFLTASFAPMRGAGQEGQVRTNFPDLARETFAQDNFTAAIDWQQGVYLAASALFRGDVKAKDVDENMATIRKSLNYASYMPASGGLKLGYAETAPEGFASSGLALVNHTGIAAVFERLIAQFDIMFDNHAYTHWYENAGVSRDMMAKARNQIATLAQSYRDAS
Protein: Small ribosomal subunit protein uS12 (30S ribosomal protein S12) (P0A7S3)
Organism: Escherichia coli (strain K12)
Function: With S4 and S5 plays an important role in translational accuracy.
Interaction partners:
- Alternative ribosome-rescue factor A
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein bS6
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein uL30
- GTP pyrophosphokinase
- Large ribosomal subunit protein uL14
Sequence:
MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
Protein: ATP-dependent RNA helicase dbp2 (EC 3.6.4.13) (p68-like protein) (P24782)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Protein gar2
- H/ACA ribonucleoprotein complex subunit cbf5
- rRNA 2'-O-methyltransferase fibrillarin
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43
- ATP-dependent RNA helicase has1
- Nucleolar protein 58
- Uncharacterized protein C1A4.11c
- Uncharacterized protein C12G12.07c
- Probable nucleolar GTP-binding protein 1
- mRNA export factor elf1
Sequence:
MSYRDNEYSGNYNGKEDGYNSRGRYGGGYRNNYSRGGGRGGFNDGASYGYDQRGQGRNFYESDGPGANLVKKDWKNETLIPFQKDFYKEHENVRNRSDAEVTEYRKEKEIVVHGLNVPKPVTTFEEAGFPNYVLKEVKQLGFEAPTPIQQQAWPMAMSGRDMVGISATGSGKTLSYCLPAIVHINAQPLLSPGDGPIVLVLAPTRELAVQIQQECTKFGKSSRIRNTCVYGGVPRGPQIRDLIRGVEICIATPGRLLDMLDSNKTNLRRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTVMFSATWPKEVQRLARDYLNDYIQVTVGSLDLAASHNIKQIVEVVDNADKRARLGKDIEEVLKDRDNKVLIFTGTKRVADDITRFLRQDGWPALAIHGDKAQDERDWVLNEFRTGKSPIMVATDVASRGIDVKGITHVFNYDFPGNTEDYVHRIGRTGRAGAKGTAYTYFTSDNAKQARELVSILSEAKQDIDPKLEEMARYSSGGRGGNYRRGGYGRGGFRRGGGYGNRNRGFTGSNSAPLARSRW
Protein: Putative lysophospholipase SPBC1348.10c (EC 3.1.1.5) (Phospholipase B) (P0CU03)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the release of fatty acids from lysophospholipids.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MYVNYIGLFAFVQISLTLAYPPGRVEISEIYDFEESSSYKGQDIDTSVLYTLSKRKPALVKRSTDASYAPFNVTCSNDNLLRPASEGLNEGEQSYINKRISKVNSELRSFISKTGLNVDLDKVVNSSDGPRLGIAFSGGGLRAMVNGGGAFNAFDSRFESDSPLSGLLQSAMYISGLSGGSWLVGSVAINNFTNITYLRDNVWNLEHSVFAPHGDNVIENLNYYNDLRKEIDQKKHAGFDCSLTDLWGRALSRKLVDAERGGPGITYSSMRNQSWFQNADYPYPIIVADSRLEEETAIPANTSIFEFTAYEFGTWDNGIKAFIPMEYVGTHLLDGVPPDKSCIHNYDNAGFVMGTSATLFNSFLLDWNENVKKNDTYYDILHAILEDLSKHQDDIAPYPNPYQNYTTSNTSVVNAFEPYDTIDLVDGGEDRENIPLWPLLHPQRFVDVVFAIDSTYNDPYGWPLGSSIVATYERVVTFNANKSVDVRGFPYIPDENTIISLGLNTRPTFFGCDGKNTTAGNHDVDNNTPPLLVYFPNYPWTYYSNISTFTMSMDDKMANGILENAFMSTTQNNNESFAVCLACAIIQRSLERKKLSTPTQCSSCFQEYCWDGTLATSTASVYDPTVMSAATTSRAPSGTTSGTASSTTSSSVASATPTHKHWWDSIFEAKENP
Protein: NAD(P)(+)--arginine ADP-ribosyltransferase 1 (EC 2.4.2.31) (Mono(ADP-ribosyl)transferase 1) (AT1) (P55806)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted, extracellular space. Note=The mature enzyme is probably secreted from granulocytes into the extracellular space.
Interaction partners:
Sequence:
MELLALRWVLLAGTLLSTSAASSALQEGDLGSITVIMDMALNSFDDQYLLCEDRMRARLQMENITEFSTNIAYAVTWRQAAAEWQKRWGHLARPMQLIREQAIALLAYSASSRMCTLFNEATRQGGRSHQDYIHSYHFKTLHFFLTQALFALRASQPRCYYVYRGVRGIRFMTQRGKSVRFGQFTSTSLRKEATVNFGQDTLFVVKTCYGVPIKQFSFFPSEDEVLIPPFEVFEVINFSNDRGSVKIQLHSKGKMSTHNCELLKPQGGQWGRGHQEVGLGLSPGLSLPVLPCRRRVWEGLGHREGDPIPAAV
Protein: Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (A0A2R8Q685)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004135}. Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Lateral cell membrane {ECO:0000256|ARBA:ARBA00004124}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}. Synapse, synaptosome {ECO:0000256|ARBA:ARBA00034102}.
Interaction partners:
- FAU ubiquitin-like and ribosomal protein S30 fusion b
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- Potassium voltage-gated channel, shaker-related subfamily, beta member 2 a.
- Voltage-gated potassium channel subunit beta-1
Sequence:
MEKPSAGMSKVGSRSTASLPPEPVDIIRSMSCYRRVKLNVGGLPHEVLWRTLDRLPRTRLGKLRDCKTHESLMEVCDDYNLEDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELKREADTLKDREGEEFDNTCCSEKRKKLWDLLEKPGSSVAAKILAIISILFIVLSTIALSLNTLPELQETDEFGQTTDNTQLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNVREAFSRGTDLLDVVVMDKGERSQDNHLSPSRWKWSSKRGTSETSSNRSFNPDQGSPSKARASSPQRLNAQKLEDMYNQMAKTQSQPNLNTKDRNSSRAGHRRDEIELGALPGQGGDPMNGGREGVVDMKSLSSIDSYISCATDFQENPRFHYSPAGGLSLPESSRFSHSPGSGLSSRVSANPSLQTTLEHETMLTPPFSGAKPLNTDGSRQQGLLGNSQKMHSVRVNPRNCAESSPSGGPLSDSSILSDHSILSPEVSVYTTASTRTPPKTPERKVLTPTVFTFHDASISKYIDADTDDEEHLRESGPSDRLLGGLSSKPRLGGYQGATNHLEAAQRLLGQNCLFPLGSSPSVGHENHVASENSRRPKGDRGHSNAFDKGL
Protein: Dynactin subunit 4 (Q5B3G3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000256|ARBA:ARBA00004529}. Cytoplasm, myofibril {ECO:0000256|ARBA:ARBA00004657}.
Interaction partners:
- Dynactin subunit 5
- Dynamitin homolog
- Arp11 homolog
- P150 dynactin NUDM
- F-actin-capping protein subunit beta
- ER membrane protein complex subunit 1
- ER membrane protein complex subunit 3
- Actin, gamma
- Actin-related protein
- Cytoplasmic dynein intermediate chain
Sequence:
MACPFPYTFISCPCADASVPDPSRKRRSRESPHKASPVKPRPQPVISDDEDEDEQTFDPRAPRSNFSLYPPEQLLYCEDCHQIKCPRCITEEILCWYCPSCLFETPSSLVRYEGNRCGRNCFNCPSCTAPLAVTALQGDPPSGEQAGPWVLSCNYCMWTTLDIGIKFDKPTNIRAQLSKLTTEPSSTTASRSRGASRSFGDLKSPLSMYSSIDEQLPSAGTNQPGEEQPTNTHTPRTRDARFAALKAFYKDQMTATNTTGVDPGDFAGQFSSPNTLQRFMVIYTQSRLFTLYGTLTPSEGLFIPNRPESEVAIIRRLASDDCGWDGVASIEQRTAQPQSFSARFVEDLLPLPTLLRTKRSKRCKSCKHILVKPEFKPQSVRYRIKLIAISYIPLPTLRPLVLPPSASQPLPPPPPDLNSLQPQKPIQLLLTLKNHMFDPVRITLATPSVTPGRVASKVTILCPQFDIGANKDAWSEALEPVAPPYERVAEAGKVWEKGRNWTTVVLEVVPGSLPGLGARRSATGTGSNSDDDDDNADNDPDDSEDAAKGVSGQFDWSGQASDPSQQIQPDEDVLEIPVFVRMEWDSDSPMESEEGGKDSLGAAAGLGVGGTKRELAYWMVLGVGRIVSLSAGSSSSS
Protein: Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R) (O08786)
Organism: Mus musculus (Mouse)
Function: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Cholecystokinin
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-11
- Gastrin
- Gastrin/cholecystokinin type B receptor
- C-C motif chemokine 28
- Guanine nucleotide-binding protein subunit alpha-14
- Guanine nucleotide-binding protein G
- Neurotensin/neuromedin N
Sequence:
MDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSAVQILLYSFIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLIPGVVMVVAYGLISLELYQGIKFDASQKKSAKEKRLSSGGGGGGGSSSSRYEDSDGCYLQKSRPPRKLELQQLSTSSSGGRINRIRSSGSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPTGVRGEVGEEEDGRTIRASLSRYSYSHMSTSAPPH
Protein: Pentatricopeptide repeat-containing protein At3g48810 (Q9M302)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Surfeit locus protein 1-like
- Surfeit locus protein 1
- Heme A synthase COX15
- Cytochrome c oxidase assembly protein COX11
- Cytochrome c-type biogenesis CcmH-like mitochondrial protein
- Replication factor C subunit 2
- ATP synthase subunit a-1
- Glycine-rich RNA-binding protein 2, mitochondrial
- Uncharacterized mitochondrial protein AtMg01280
Sequence:
MYLKEGCSLLLKVQKPLIPFVLNTNLNVNHLLTESPNHAEIKELDVVKRLRQESCVPLALHFFKSIANSNLFKHTPLTFEVMIRKLAMDGQVDSVQYLLQQMKLQGFHCSEDLFISVISVYRQVGLAERAVEMFYRIKEFGCDPSVKIYNHVLDTLLGENRIQMIYMVYRDMKRDGFEPNVFTYNVLLKALCKNNKVDGAKKLLVEMSNKGCCPDAVSYTTVISSMCEVGLVKEGRELAERFEPVVSVYNALINGLCKEHDYKGAFELMREMVEKGISPNVISYSTLINVLCNSGQIELAFSFLTQMLKRGCHPNIYTLSSLVKGCFLRGTTFDALDLWNQMIRGFGLQPNVVAYNTLVQGFCSHGNIVKAVSVFSHMEEIGCSPNIRTYGSLINGFAKRGSLDGAVYIWNKMLTSGCCPNVVVYTNMVEALCRHSKFKEAESLIEIMSKENCAPSVPTFNAFIKGLCDAGRLDWAEKVFRQMEQQHRCPPNIVTYNELLDGLAKANRIEEAYGLTREIFMRGVEWSSSTYNTLLHGSCNAGLPGIALQLVGKMMVDGKSPDEITMNMIILAYCKQGKAERAAQMLDLVSCGRRKWRPDVISYTNVIWGLCRSNCREDGVILLERMISAGIVPSIATWSVLINCFILDDIVRAHDQFTI
Protein: Transmembrane protein 201 homolog (Spindle-associated membrane protein homolog) (Q22747)
Organism: Caenorhabditis elegans
Function: Plays a role in nuclear migration in hypodermal cells.
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:25057012}; Multi-pass membrane protein {ECO:0000255}. Note=Localization at the nuclear envelope does not require lmn-1. {ECO:0000269|PubMed:25057012}.
Interaction partners:
- Sun domain-containing protein 1
- Nuclear migration and anchoring protein unc-84
- MEiosis-to-MItosis transition associated
- Barrier-to-autointegration factor 1
- KASH
- Lamin-1
- Kettin homolog
Sequence:
MEVAAAVGVIASVPILYKAIRPRIKTSVECWFCRKSTKVEYQQRNSFTCPSCEQYNGFTEDGDYNRRIPGQAWTTPKRYCEPGKMQSEKPSTFLDRFGGVNMSPKASNGLCSECNLGQEIIMNKVAEFEPIDEDRWNEELEDYRYKLERMYQLCPRCTIQVHGKLEEDKKKYSYLLKVKYKLKHAIGSTLREVMNNQKRSRRFFFAGGSTCEALHFGCLISSIILFLANIDFLQQDAGASLINLPKALQDILPEVYKYSFVINFLIFTTHLIAAFNNKCRVTLPDLLLPILLILAMLTVLTSSDNLSQDVALVRGACASFSTILSMAVTLLPRKKLHKKRPNKIVSSAFSVASTPISQCSSQNSRNASLLDHDHTILRRSPHTPSASPPAMNSSPPLLREITNGPVWSAMRSRENKENMQSYQTKPNNHVESMDWDDSESMAAQSVAQSTRSSHFKPGLLSRNINERMTAQQLTPSVANLNLDTRSVDSPSIFSRQHRQMAQQQNHTPTRSLFGPPRSMVASQYDRSHYMAPEAHTRPGSVFTSVSQQDGHSTVSGAWQCRVIGILFALVFIVLIMQIGLFYVLFTRN
Protein: SMP-LTD domain-containing protein (Q4GZ88)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSLLVALVRVIGFVLFFTALLRVKKTRVRHLPSRRTRVSRHQGETCIWLERLTSAVFDIFYSAMREGNEPDTREQRGQSQNNSCEGDFAANSARREDKSCGGGGGVGGDAWRFVRLIEEHVEALLEDRGIAACATFNIHSLGDKPPIIRAIRVINRTGMESVPPGSAAPATGSGSPGSGDKDTATPSTVVVPPALNANTSTSINATGVKPVVSHKTKLRPSQLTLYPTGDGTEKWHNEMHPDEAVAAAPSAANPILSCLPPLPATAIELEAEVEYAGDIDVRLQADICLARGRRLPVFIRVSDVEYIKAHVRLHATLKHENATMDTQRKPYLQCTLWLESEPTFSFKMSTVFSFHGIRDFFAVPVVAKFLFLRLVNYRMLYPRGAGLSFNIPLPEDVVDGGVYPWFSPMDDVGTVATPSLNSFMMGRGAL
Protein: G-protein coupled receptor 135 (Q8IZ08)
Organism: Homo sapiens (Human)
Function: Orphan receptor. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization.
Subcellular location: Cell membrane {ECO:0000269|PubMed:28827538}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:28827538}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome. {ECO:0000269|PubMed:28827538}.
Interaction partners:
- Platelet-activating factor receptor
Sequence:
MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGPGLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTAVTKQPKSEAGDTSL
Protein: Protein naked cuticle homolog 2 (Naked-2) (Protein naked cuticle homolog 2-A) (Naked-2A) (A4ZNR4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Cell autonomous antagonist of both the canonical and non-canonical Wnt signaling pathways.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q969F2}. Cytoplasm {ECO:0000250|UniProtKB:Q969F2}.
Interaction partners:
Sequence:
MGKLHSKHACKRRENPEGDSFVVNGFIAKRAAEEGERYGNNLKDYKNEELKDSQPTLLHCPLQVVLPPEKAEGCESFLQYLSPDDEERDAQKVTKRISLQDLECNVSLAEDNRQEWVFTLYDFDNSGKVTKEDMSSLMHTIYDVVDASVKHSCNSKRRSLRVKLSVTPEPAARRRDATHTERETSHLSQVEPVRSEEHRSADRRQSTHIRGQTEAHEGNHYCVDENTERRNHYLDLAGIENYTSRFDSSSPDADQDPPSRSSHSQSRPHSQEPETHVYQRRSQLMEPCVAPDPRLRTGPQLIRSRSPKGSSRYPGVIPNVTKTSKCHGHHQPISAGQDVYHLTQQSHTHAHTPSGLQHSHSRRIRSRAREQQALTPVKNTNATALVQRHEHHHHHEHHHHHHYHHYHQT
Protein: LYSozyme (Q09975)
Organism: Caenorhabditis elegans
Interaction partners:
- C-type lectin domain-containing protein
- C-type LECtin
- VWFA domain-containing protein
- Polypeptide N-acetylgalactosaminyltransferase 4
- CUB-like domain-containing protein
- Saposin B-type domain-containing protein
Sequence:
MLLKSVALLSVLAVLCHSASVSVKVLPFVDSSLPVKFREVIAEAAPRVPPNLASYAFAVDLSVPVSLSQLQCLKQAGYSAVFVRAYNPAGQGSFDTNSCNTIQNAYNAGLGTEIYMTPQPASSKQGYQQLDEIYQGLTARGITIRSVWIQVTSPTNWPSNANNNVNFINSIVSRARQYGMTVGIYTSYYDWNQITNGWSSIGNDVLLWYWNVLGGGVNGETPASFADFRAFGCWTTPSVKQFAQVEQVCQFTVNRDVYAAGTMLKAADAVEEDGKIYAGGFIQGSQ
Protein: DNA replication licensing factor MCM2 (EC 3.6.4.12) (Q8ILR7)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- DNA helicase
- DNA helicase
- DNA replication licensing factor MCM3
- DNA helicase
- DNA replication licensing factor MCM6
- DNA helicase
- Origin recognition complex subunit 1
- MCL1 domain-containing protein, putative
- ATPase AAA-type core domain-containing protein
- Origin recognition complex subunit 2
Sequence:
MEDKKKLEEDLESNKYDIDEEDLLEDEGRLNEEERQAELEGESLFEEDEGFIFGADDEKKEMQKLRNLGLDNDDYDDDFIDDELDYEDNLKARRAAERHMQMQRKQEGKYEKNKFWKTLEDQLEGDDEEEDIFDKVAEKVAKRRENLHLTAEETDIPDLSNLESAKICLSVNPKDVVFDERYQQAADTCFRYFLHKFSLKDSMGLNIDESNTELHEEEHMNSSHQYYIDKIEKMILNDKHTLIVSAKHLIQFHCENLVQWIEFKPEQILEVLHECLMVEAYRISPKLYKGRICKVVLRDWPYSTQLRNLRCTELNTLIKVTGVCIKRGYVLPKLRVMYLKCNSCDTTLSEVPIYFADGKKPVLPRRCPHCQSATFSVDRIKTAYTDYQKITLQESPCSVPAGRAPRQREVVVTGDLVDKVKPGEEVEVLGIYKTKYDIGLNIKYGFPILQTEIEANNIERKEDIQLSELTEDDIKDILKLSKDPNIRERIITSIAPAIWGHKDIKTSIAYALFGGVQKGGDKSFSKNNETNNFGVQNRDILNNFKGGHTIRGDINVLLLGDPGLGKSQVLQYVHKTNLRTVYTTGKGASAVGLTAGVRKDHTTNEWTLEGGALVLADEGICIIDEFDKMTDKDRVSIHEAMEQQSISISKAGIVTTLRARCAVIAAANPIYGRYDPSLTFKENVDLSDPILSRFDLITVLRDIPNVDEDFYLAEYVVTNHQLSHPKLENTQNYQKRIENLKNVIVSSSAYEPIPQDLLQKYIIYARTNCKPSLSDVPYAEISAKLSNFYSRVRQKASASGGYPLTLRHIESIIRIAEANAKMRLSHQIYSKDVDYAIATLLESYVSCQRFAVAKQLSKEFARYRALFRGGYEVLRELLRRTVQQMIQRQNLKNASAKDFQNDSESGTESEAEILNPNNVFLPLHIFMKTAMQNKFSEYQVVNWMKSKVFNEHYAVIKRDGVEGIISKKFKV