wanglab/gogpt-training-data huggingface dataset:
Protein: OCIA domain-containing protein 1 (Ovarian cancer immunoreactive antigen domain containing 1) (Ovarian carcinoma immunoreactive antigen) (Q9NX40)
Organism: Homo sapiens (Human)
Function: Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer.
Subcellular location: Endosome {ECO:0000250|UniProtKB:Q9CRD0}.
Interaction partners:
- Complex I assembly factor TIMMDC1, mitochondrial
Sequence:
MNGRADFREPNAEVPRPIPHIGPDYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLILACIMGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGQARRSSPPGHYYQKSKYDSSVSGQSSFVTSPAADNIEMLPHYEPIPFSSSMNESAPTGITDHIVQGPDPNLEESPKRKNITYEELRNKNRESYEVSLTQKTDPSVRPMHERVPKKEVKVNKYGDTWDE
Protein: Retinol dehydrogenase 14 (EC 1.1.1.300) (Alcohol dehydrogenase PAN2) (Short chain dehydrogenase/reductase family 7C member 4) (Q9HBH5)
Organism: Homo sapiens (Human)
Function: Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol. Shows a very weak activity towards 13-cis-retinol. Has no activity towards steroid.
Interaction partners:
Sequence:
MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
Protein: Abasic site processing protein (EC 3.4.-.-) (Q9HVF7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- NADPH-dependent FMN reductase-like domain-containing protein
Sequence:
MSGRYALFRWNPSLAALPGFPADWRAQWNISPANQVLMVREDAGARRADLARWGLTPAWLTDLSRTPSHARAETLAEQPMFREAFQQRRCLLPANGFYEWRGVRKRPYWVSTGERLLFFAGIWEAYPVHGQTWLSVAQVSQAAAEFRRPLLLDEAEQDTWLAPDTPLPALISLLAKPQPNLRSVALAGFVNKPETDGPECLTPA
Protein: Periphilin 1 (F8W6A0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMDHDGTPENEGEETAQSHDASNHTIVGLGPNQVPEMKETTLQAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDITWGMLKKTTQEAERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENKQ
Protein: tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase) (Q53H54)
Organism: Homo sapiens (Human)
Function: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.
Interaction partners:
- Multifunctional methyltransferase subunit TRM112-like protein
- tRNA wybutosine-synthesizing protein 3 homolog
- tRNA wybutosine-synthesizing protein 4
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1
- tRNA
- tRNA wybutosine-synthesizing protein 5
- 18S rRNA
- 18S rRNA aminocarboxypropyltransferase
- tRNA methyltransferase 10 homolog A
Sequence:
MRENVVVSNMERESGKPVAVVAVVTEPWFTQRYREYLQRQKLFDTQHRVEKMPDGSVALPVLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRGVKWSAELEADLPRSWQRHGNLLLLSEDCFQAKQWKNLGPELWETVALALGVQRLAKRGRVSPDGTRTPAVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLSNIADRVILGLIPSSEEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEHWLYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAESAETRIATLLQQVHGKPWKTQILHIQPVKSYAPHVDHIVLDLECCPCPSVG
Protein: Presenilin (EC 3.4.23.-) (M9PFS2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU361148}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361148}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU361148}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361148}.
Interaction partners:
Sequence:
MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI
Protein: Uncharacterized protein (Q57W89)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Gar1/Naf1 RNA binding region
Sequence:
MEAVVAVDGKRPSPATLFIHENTNYNGREAGAACVPMRVNDSITVQQLADEYCITSVVECDATGSVQPRAVALDSPLDVLHGGKYYIARRDVKHFAREPRVTFRGKVTVREFNATHGVIGREGETNANRGQAVAADPVGVAPSRKRPEREEDLFDSGTRTEIYAKEYEFVPFVGDLYNDGRNGMIHLKDVKKLCESVDLDEVEFRARHVQAEKILTHAKQLLLSYADGNGGRTSPEY
Protein: Synembryn (Protein Ric-8) (H0YHS3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}.
Interaction partners:
Sequence:
XASGGARRLPGGSGLGAQSGRGSPAPAAMDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKSDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGL
Protein: Leucine-rich repeat protein (LRRP) (Q582H5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGCNLSSSTKNVNPFGVKGVHVGRDGDVDLTSRSISYFGLDFVGLINTGELHTPRKLHLTDNKLYTLGKEMTLLPDIEEIYIDCNIFERLPVVLGDMPRLCVVDASSNNLGHHVHALDAVSRIANLTRLVLRNCSLTTIPACVLRCPVLKELDVSNNGSLNFGGVQFSQLPMLVRLFIADCGIIGELPNGVRNLQSLETLDVSGNVFEFENPDFFGEFLCASLTELHLRDLYLAAVPRVVIKLRKLATLDLSRNPLETLDVIAGRLVREFTSRGSMKTSISSNLINEHNDDATSVGSQSSAAKSFGQNNRKGCIVAVPQPIPLKTLSLRACSLRTLPKYFHRLTSLVKLDLSDNDQLDDPNLTFISFKHLQELNIVGCPFAVNIRGAKNEWLDIGSLGSLHTLHWESWKGGRNISPYRTRVPLEICGLNLQRINCITLRKGLFVGDTVQTMVNLLMDGYFKVDIAIDDELVPSHLGAVCTLHPLGWFFFSSGEAEEGPTGNNDKSGRCVGNGGGKDEECSAKKPQVADPGENVAPFFSVGNHPSDGKLRRDVLQIVISRYIFFLAMQAANFKAVIVPPVDVMAIHYAQMTQDPVAYRRDCEAVCRQVLNCNYRMLFLQKHEDPQGVKETLAASKHVWDRMIRTVQKDLHWLHYDFWELRAKQNPSSRNALQDGDTVSSIEDEVRDILATFGVSGFINGKPLASSVVGNLDGLHNVNSVADLSAVLDPFITAHFQNQSMDRFAVSLQRFFSMNNHFIEHEEKLKVQFMDWTRYVKYLALYAQINRLKDPKIDTDDGDQAATELKNLSIFSSDSYLPRPQKSIAPLQAALRRSRQADSSKPSSVHGHQNGTDTGNTYHGHNGPPNKKEMFKSQPPSKRPSVLSRRSDTEFHGHRRQRQLSTTDPVPTIGITLLLHCHRTDHVKYKEVLHLLGIDNVDVMWEETTDAVDETMRSWNTLYGEHYVEDVNIAFVSYAAKYKAGDNTHVDPTSRDHIQTSAAVSHRRTKSKRSDKPYREVSFCCADSQKGIY
Protein: Growth hormone (Somatotropin precursor) (A7LFX3)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MARALVLLSVVVASLLFSQGATFESQRLFNNAVIRVQHLHQLAAKMMDDFEEALLPEERKQLSKIFPLSFCNSDSIEAPAGKDEAQKSSVLKLLHTSYRLIESWEFPSRNLGNPNHISEKLADLKMGIGVLIEGCVDGQTGLDENDSLAPPFEDFYQTLSEGNLRKSFRLLSCFKKDMHKVETYLSVAKCRRSLDSNCTL
Protein: RNA helicase (EC 3.6.4.13) (A0A2R8YFS5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Protein: Natural killer cell receptor LY49W1 (Natural killer cell receptor Ly-49W1) (Q9EP57)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MSEQEVTFSAVRFHKSSGLQNRVRLEETGKPQKAGLRVCSVPWQLIVIALGILISLRLVIVSVLVTNIFQNSQQNHELQETLNCHDKCSTTTQSDINLKDELLSSTSIECRPGNDLLESLHKEQNRWYSETKTFSDSSQHTGRGFEKYWFCYGIKCYYFVMDRKTWSGCKQTCQISSLSLLKIDNEDELKFLQNLAPSDISWIGFSYDNKKKDWVWIDNGPSKLALNTTKYNIRDGLCMSLSKTRLDNGDCGKSYICICGKRLDKFPH
Protein: Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase) (Q9BVK2)
Organism: Homo sapiens (Human)
Function: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol before it is transferred to the nascent peptide (By similarity). Required for PKD1/Polycystin-1 maturation and localization to the plasma membrane of the primary cilia (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:15235028}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Dol-P-Glc:Glc
- Dol-P-Glc:Glc
- Dol-P-Man:Man
- Dol-P-Man:Man
- Phosphomannomutase 2
- Dolichyl-phosphate beta-glucosyltransferase
- Neutral alpha-glucosidase AB
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- Chitobiosyldiphosphodolichol beta-mannosyltransferase
Sequence:
MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ
Protein: Homeodomain-like superfamily protein (F4J959)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGEEVQMSDYDVSGDGDRVSEWEMGLPSDEDLASLSYSLIPPNLAMAFSITPERSRTIQDVNRASETTLSSLRGGSSGPNTSSSNNNVEEEDRVGSSSPGSDSKKQKTSNGDGDDGGGVDPDSAMAAEEGDSGTEDLSGKTLKRPRLVWTPQLHKRFVDVVAHLGIKNAVPKTIMQLMNVEGLTRENVASHLQKYRLYLKRMQGLTNEGPSASDKLFSSTPVPPQSFQDIGGGGGSSGNVGVPIPGAYGTQQMMQMPVYAHHMGMQGYHHQNHNHDPYHQNHRHHHGAGGNGSWCLQNFLSFAEFSTAKSQIASVQERIIQSIM
Protein: Septin-7 (Q6GLZ5)
Organism: Xenopus laevis (African clawed frog)
Function: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis (By similarity). Plays a role in ciliogenesis and collective cell movements including convergent extension during gastrulation. Controls cell elongation but not polarization during convergent extension.
Subcellular location: Cytoplasm {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cleavage furrow {ECO:0000250}. Midbody {ECO:0000250}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:20671153}.
Interaction partners:
Sequence:
MVAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYAPDYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDGLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKYDTGEGMSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEKVNWETQQRILEQQNTSRTLEKNKKKGKIF
Protein: Metacaspase-5 (AtMC5) (EC 3.4.22.-) (Metacaspase 2b) (AtMCP2b) (Metacaspase-6) (O64518)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. May be involved in the modulation of programmed cell death activated by oxidative stress.
Interaction partners:
- Putative NAC domain-containing protein 94
- NAC domain-containing protein 89
- D111/G-patch domain-containing protein
- Remorin family protein
- bZIP transcription factor 28
- bZIP transcription factor 60
- Aspartic proteinase 39
Sequence:
MAKKAVLIGINYPGTKAELRGCVNDVRRVHKSLVDRFGFSERNITELIDTDESSTKPTGKNIRRALLNLVESAKPGDVLVVHYSGHGTRLPAETGEDDDTGYDECIVPCDMNLITDDEFRDLVEKVPKEAHITIISDSCHSGGLIDEAKEQIGESTKKKPKKESGGSSGLGIKGFVREAVEEALESKGIAIPHHKDEKDENKTKELKLEDGAKVHVVNKSLPLQTLIDILKQNTGNNDIEVGKIRPTLFNVFGEDASPKVKKFMKVILTKLQEGKTEGGILGMIGKLAQEFLKHKLNDDEEYVKPAMKTHVGNKQEVYAGASNGSLADNGILISGCQTDQTSADASPQGHPEMAYGAFTNAVQIILEETKGMITYKELVLKARKLLKKQGFSQRPGLYCSDSFVNAPFIC
Protein: Ribonuclease J (RNase J) (EC 3.1.-.-) (Q72DQ3)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01491}.
Interaction partners:
- Metallo-beta-lactamase family protein
- 4-hydroxy-tetrahydrodipicolinate synthase
- Lipoprotein
- Fumarylacetoacetate hydrolase family protein
- FtsK/SpoIIIE family protein
- Phosphoesterase
Sequence:
MAEHAPHFTITPLGGLGEIGLNCQVWSTADSTVLIDCGLMFPDDYHLGVDVVIPRFDHILQQRDKVRGIILTHGHEDHIGALPWLVPHLRGIPIFGSRFTLALVEHKLREHGLADRVEFVPVTPGTPLALGDMTFHFLPVCHSIIEGYAVGVETPVGRVLHTGDFKIDPHPLEGSGTDLDLFRSFAGDEGVRLLLSDSTNIEREGHSLPEREILSSFRHIFTEAQGRIVITLFSSHIQRIQEVFDLAAEFGRTVVVSGRSLMTNIELAREHGFLRVPPALHMDAAGLPPVADRDMVLLVTGSQGEPLSALSRITMGEHKHLTIHEGDTVVMSSRIIPGNARAITRLINQIYRLGAEVYYDKFRAIHASGHAHRDELRAMIETMRPQCFVPVHGEYRHLVKHARLAQECGVAPERAFILENGDPLTLLPQGVRLGERIHVESILVDGKGVGDVGHSVLKERHILGGEGMVIVVLVVDEVTWDVLHGPEMLSKGFVFEQHYNHVLEDAKCIVLDIFENIPPGETERLQDRIRSALRRFFRKVLERDPIVVPVITTI
Protein: S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] (P21182)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the decarboxylation of S-adenosylmethionine, a key step in the biosynthetic pathway for spermidine and spermine. It is essential for normal growth, sporulation, and maintenance of ds-RNA virus.
Interaction partners:
- Spermidine synthase SPE3
- Spermine synthase SPE4
- Ornithine decarboxylase
- S-adenosylmethionine synthase 2
- S-adenosylmethionine synthase 1
- Deoxyhypusine synthase
- Arginase
- Deoxyhypusine hydroxylase
Sequence:
MTVTIKELTNHNYIDHELSATLDSTDAFEGPEKLLEIWFFPHKKSITTEKTLRNIGMDRWIEILKLVKCEVLSMKKTKELDAFLLSESSLFVFDHKLTMKTCGTTTTLFCLEKLFQIVEQELSWAFRTTQGGKYKPFKVFYSRRCFLFPCKQAAIHQNWADEVDYLNKFFDNGKSYSVGRNDKSNHWNLYVTETDRSTPKGKEYIEDDDETFEVLMTELDPECASKFVCGPEASTTALVEPNEDKGHNLGYQMTKNTRLDEIYVNSAQDSDLSFHHDAFAFTPCGYSSNMILAEKYYYTLHVTPEKGWSYASFESNIPVFDISQGKQDNLDVLLHILNVFQPREFSMTFFTKNYQNQSFQKLLSINESLPDYIKLDKIVYDLDDYHLFYMKLQKKI
Protein: Uncharacterized protein, isoform A (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform E) (Q0E949)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Growth factor receptor-bound protein 2
Sequence:
MMRYSEISRDLSTDNLRYSELSRKPTTDYNGYTGQAYAATQFKQSSPPPPPSQQQQQPTRVSKQRSPNTNGSAHTMACLRQEKTYKEQQMEPPSMQPQASKTLNIKSTRRKNSIGCLNSFSSSPDSPGCYYTIAASAAPPSKSQSLPAHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYLESLRLPCIPYLGLFLTDLIYIDLAHPHKGGLEPEQRRNKMNNILRVISNYQQSNYKHLQKHEATQKYLTSIRYIEELQNIFEEDQYKRSLNLEPASPSGPSSSSCSSKESFNVEVVTPALGCLNLSPAKTIGSMRMASGTKFVPGHRKCRSLGTKFRSSSLPRNFAEKCQCCIVMIAPGIGTISNKRCRCRRIFGKIATHNHSDGHPHHLHLELDPSQVQPRHHLLDDSVLEHSDALSQADLTSLESAEGIMCDFTGSDCDLMSPEAAAAMHGCVRRKTVQKEGRKPAVASWQRYWLQIWANSLVYFPPKSFKGSERNDFKREPCKVCPLDGWYAHVSDNTKHKNTFELCHRTLGTVYRFRTDSPQMTHLWSNAICKLATMRVPKPLPTNLMSFE
Protein: DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (B44.5) (DNA-directed RNA polymerase II 45 kDa polypeptide) (P16370)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft. Seems to be involved in transcription termination.
Subcellular location: Nucleus.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- Transcription initiation factor IIF subunit alpha
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase II subunit RPB7
- Mediator of RNA polymerase II transcription subunit 14
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- Mediator of RNA polymerase II transcription subunit 17
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerases I and III subunit RPAC2
Sequence:
MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYSNASQMGNTGSGGYDNAW
Protein: Troponin I, slow skeletal muscle (A0A060VTL6)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Troponin T type 2b
- Uncharacterized protein
- Uncharacterized protein
- Troponin T type 3a
- Uncharacterized protein
- Troponin T, slow skeletal muscle
- Troponin C, slow skeletal and cardiac muscles
- Troponin C, slow skeletal and cardiac muscles
- Troponin T, slow skeletal muscle
- Troponin C, slow skeletal and cardiac muscles
Sequence:
MADAPKPKEKSKISSARRLGLKIRLLTVAGQMLEVETEEKKREREEALAERVPPLKLSGLSVDELMDLCKDLHRKIDVVDEERYDVGLKVTKTDKECHELGLKIIELQSKFKKPSLKRVKISAEMMLSVLLGSKHKETIDFKSNLKTVKKAEEKKEEVTDWRQNVDAMSGMEGRKKMFDA
Protein: Calcium-binding protein 7 (CaBP7) (Calneuron II) (Calneuron-2) (Q86V35)
Organism: Homo sapiens (Human)
Function: Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000305|PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305|PubMed:19338761}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:19338761}. Cell membrane {ECO:0000305|PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305|PubMed:19338761}.
Interaction partners:
Sequence:
MPFHPVTAALMYRGIYTVPNLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFVTLLGPKLSTSGIPEKFHGTDFDTVFWKCDMQKLTVDELKRLLYDTFCEHLSMKDIENIIMTEEESHLGTAEECPVDVETCSNQQIRQTCVRKSLICAFAIAFIISVMLIAANQVLRSGMK
Protein: Dysferlin (D4A6X1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004401}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}. Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004483}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004483}.
Interaction partners:
Sequence:
MLCCLLARASNLPNVKKDRRSDPVASLIFREAKIPLQEVLATPSLSASFNAPLLDSKQQPTGASLVLQVSYTPPPGAAPLFPPPASLAPSPTLPDMDLVADTGGEEDTEDQGLTGDEAELFPDPSVAVGPGGPTTPKKPPSHPPPHYPGGKRKRSSAPPRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIQKGNSPLFNETLFFNVFDSPLELFDEPIFITVVDSRSLRTDALLGEFRMDVGTVYREPRHAYLRKWLLLSDPDDFSAGARGYLKASLCVLGPGDEAPLDKKDPSEDKEDIEGNLLRPTGVALRGAHFCLKLFRAEDLPQMDDAVMDNVKQIFGFDSNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRVMDWDRLTHNDTVATTYLGMSKISATGGEIEEEPAGVLKSPATDLDDNLGFLPTFGPCYVNLYGSPREFTGFPDPYAELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDTTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRVETQNQLLRIADRLEANLEQVHLALKAQCSSEDVDALVAQLTDELLADCSQPLCDIHEIPSATHLDQYLFRLRSRHLSQIKEAALALKLGHSELSTALEQAEDWLLHLRALAEEPQNSLPDIIIWMLQGDKRVAYQRVPAHEVLFSRRGPSYCGRNCGNLQTIFLKYPMEGMPGPRMPVQIRIKLWFGLSVDEKEFNQFAEGKLSVFAETYENQTKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWAWAGDWFVCPEKTLLHDADAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPDRKPKHWVPVEKMYYTHRRRRWVRLRRRDLSQMEALKKHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGMVDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYLYQARDLPAMDKDSFSDPYAIVSFLHQSQKTVVEKNTLNPTWDQTLIFYEIEIFGEPASVAERPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPAGELLAAFELIQREKPAIHHIPGFEMHETSRILDETEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNIKSYQMASVSSPSLVVECGGQTVQSCVIRNLRKNPNFDVCTLFMEVMLPREDLYCPPIVVKVIDNRQFGRRPVVGQCTIRSLENFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPVQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFGGLSDFCNTFKLYRGKTQEDTEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIIRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVIDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVTFQDKEYTIQEIEAGRLPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWIDIFPKVLGRPGPPFNITPRKARRFFLRCIIWNTKDVILDDLSLTGEKMSDIYVKGWMVGFEEHKQKTDVHYRSLGGEGNFNWRFVFPFDYLPAEQVCAVAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAEKCSLDQLDDTFHPEWFVSLFEQKTVKGWWPCVTEEGAKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRCAIILFIILFILLLFLGVFVYAFPNYAAMKLVKPFR
Protein: CG11153 (Q8STH7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
LIPGHENAQSVPTHHHSHPQSEAFSTHKMALAPMWSTAAVAAAHIQAALAAAAVAAANNNKNSSHFSNNTNIVGLATRGNELLNTDSDPQMEIGETRRGGNGGSCRSRPESPTYENPPYEILSYSHNTPPESPHGRTADCSKNFSPSPTDNLSIASVSEAQDSEMDAPLNLSKPKGSPSSSPNSSSQRDHCENLTPVVSSPPLSWHQGQPHYAEIELPLLKSH