wanglab/gogpt-training-data huggingface dataset:
Protein: Protodermal factor 1 (Q9S728)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the regulation of meristem growth.
Interaction partners:
- Defensin-like protein 18
- Defensin-like protein 178
- Defensin-like protein 176
- Defensin-like protein 10
- Protein SPIRAL1-like 3
- HAD superfamily, subfamily IIIB acid phosphatase
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
- Homeobox-leucine zipper protein MERISTEM L1
- Homeobox-leucine zipper protein PROTODERMAL FACTOR 2
Sequence:
MRGMVSFAVWALFAALLSQQLFASVASVRFEDAKTYYLSPPSGSHGTPPSHTPPSSNCGSPPYDPSPSTPSHPSPPSHTPTPSTPSHTPTPHTPSHTPTPHTPPCNCGSPPSHPSTPSHPSTPSHPTPSHPPSGGYYSSPPPRTPVVVTPPSPIVDPGTPIIGGSPPTPIIDPGTPGTPFIPAPFPPITGTCDYWRNHPTLIWGLLGWWGTVGGAFGTVSIPSSIPGFDPHMNLLQALSNTRSDPIGALYREGTASWLNSMVNHKFPFTTPQVRDHFVAGLSSNKAATKQAHTFKLANEGRLKPRV
Protein: Hepatic and glial cell adhesion molecule a precursor (Zgc:112363) (Q502A9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00046288}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00046288}.
Interaction partners:
Sequence:
MKAEREASCKETAIPSLFLLLWLFIFSLADVGGVNISSPSPVVRGTLGGSALLSVTYTSTSLDHPVIKWQLKRDKPVTVVQSIGTDIIGNLRPEYRGRILLYENGSLLLHNLRLSDEGSYEVEISITDDTFTGERHVNLTVDIPVSRPFIHMVASSVLELTEFFILNCTHESGTKPTYSWLKGGKSLTNDSRLLLSHDQKVLTISRVMMSDDDVYSCRVENPISSMKSMPVKLTVYRRSSLYIILSTGGIFLLITLVTVCACWKPSKKKREQLARQSVAEQSNGSHEVVDIVPARNYHNRRNPGGLYVLNETDFPGGTDESSGNYINPIDPLSPPCYPSMAPPPSSQSPDAYMHSGRRYPRTPVPSPPPTPHGTFSPPLSCPIYPGSLTRKPHPPRLSSSPPHAEDPPTDGENTMHHHSLPR
Protein: Integrin subunit beta 1 binding protein 1 (C9JZ07)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFRKGKKRHSSSSSQSSEISTKSKSVDSSLGGLSRSSTVASLDTDSTKSSGQSNNNSDTCAEFRIKYVGAIEKLKLSEGKGLEGPLDLINYIDVAQ
Protein: Conserved membrane protein (O06583)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- 2-methylcitrate synthase
- Putative flavin-containing monoamine oxidase AofH
- Probable PhiRv1 phage protein
- DUF1023 domain-containing protein
- propanoyl-CoA C-acyltransferase
- Possible protease IV SppA
- 2-methylcitrate dehydratase
- Probable conserved Mce associated transmembrane protein
Sequence:
MGFLQPRLPDIDLAEWSQGSRSQKIRPMAQHWAEVGFGTPVLLHLFYVAKILLYVLVGWLIVLTTKGIDGFTDAAAWYAEPIVFEKVVLYTMLFEVIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPWTRGTKRKPVDVALYALLVMMLLSALFTDGAGPIPELGTTVGLLPAWQIVLILLLLGVLGLRDKVIFLAARGEVYATLTVTFLFGRLNGIDMIVAAKLVFLVIWIGAATSKLNRHFPFVISTMMSNNPLFRPRFIKRMFFKKFPGDLRPGLLSRIVAHVSTVIEMCVPVVLFVAHGGWPTVVAATIMVCFHLGILTAIPMGVPLEWNVFMIFGVLSLFVGHACLGLADVKNPVPLAILIAVVAGIVIAGNVFPRKISFLAAMRYYAGNWDTTLWCIKPSAEDKINRGIVAIASMPAAQLERFYGKDRAQIPMYLGYAFRAMNSHGRALFTLAHRAMAGHDEDDYVITDGERVCSTAVGWNFGDGHLHNEQLIAAMQQRCGFQPGEVRVVLLDAQPIHRQTQEYRLVDAATGEFERGYVRVADMVNRQPWDDDVPVHVLPG
Protein: Inner membrane protein YjdF (P39270)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MTRTLKPLILNTSALTLTLILIYTGISAHDKLTWLMEVTPVIIVVQLLLATARRYPLTPLLYTLIFLHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDKLGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQGADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITG
Protein: Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity tyrosine phosphatase YVH1) (Q9UNI6)
Organism: Homo sapiens (Human)
Function: Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro) (By similarity). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates.
Subcellular location: Nucleus {ECO:0000269|PubMed:10446167}. Cytoplasm, cytosol {ECO:0000269|PubMed:10446167}. Note=Primarily nuclear. Detected in a mesh-like pattern in the cytosol. {ECO:0000269|PubMed:10446167}.
Interaction partners:
- Mitogen-activated protein kinase 1
- Protein c-Fos
- Mitogen-activated protein kinase 14
- mRNA turnover protein 4 homolog
- Transcription factor Jun
- Mitogen-activated protein kinase 8
- Cyclic AMP-dependent transcription factor ATF-3
- Protein FosB
- Mitogen-activated protein kinase 3
- Very-long-chain 3-oxoacyl-CoA reductase
Sequence:
MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREGSGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI
Protein: Putative AKH receptor (Q71EB3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MAKVAEENDHRDLSNWSNVNDTNGTIHLTKDMVFNDGHRLSITVYSILFVISTIGNSTVLYLLTKRRLRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRVLKDVIAERFRRSNDDVLSRAKKRTLKMTITIVIVFIICWTPYYTISMWYWLDKHSAGKINPLLRKALFIFASTNSCMNPLVYGLYNIRGRMNNNNPSVNNRHTSLSNRLDSSNQLMQKQLTNNSLLNGRGQVMAAAVSATTKLANVVSLKGTANGNGSAAAAGTVPITPPLTVTIAPLATDDEANDDSCLSAVTIRCQDQSPIRQKCGESIELTSVVK
Protein: Type 3 secretion system secretin (T3SS secretin) (Type III secretion protein YscC) (Q56974)
Organism: Yersinia pestis
Function: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
Subcellular location: Cell outer membrane {ECO:0000255|HAMAP-Rule:MF_02219}.
Interaction partners:
Sequence:
MAFPLHSFFKRVLTGTLLLLSNYSWAQELDWLPIPYVYVAKGESLRDLLIDFSANYDATVVVSDKINDKVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKLALQRSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQAKVEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALGSLIDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHHETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIDGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYLGALFRRKSELTRRTVRLFIIEPRIIDEGIAHHLALGNGRDLRTGILAVDEISNQSTTLNKLLGGFQCQPLNKAQEVQKWLSQNNKSSYLTQCKMDKSLGWRVVEGACTPAESWCVSAPKRGVL
Protein: Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit) (O43424)
Organism: Homo sapiens (Human)
Function: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex.
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q61625}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cerebellin-1
- Delphilin
- Neurexin-1
- Neurexin-2
- Cerebellin-3
- Glutamate receptor 2
- Glutamate receptor 1
- Glutamate receptor ionotropic, kainate 2
- Beclin-1
- Cerebellin-2
Sequence:
MEVFPFLLVLSVWWSRTWDSANADSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMRGVVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYGIALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSFAGVFCILAAGIVLSCFIAMLETWWNKRKGSRVPSKEDDKEIDLEHLHRRVNSLCTDDDSPHKQFSTSSIDLTPLDIDTLPTRQALEQISDFRNTHITTTTFIPEQIQTLSRTLSAKAASGFTFGNVPEHRTGPFRHRAPNGGFFRSPIKTMSSIPYQPTPTLGLNLGNDPDRGTSI
Protein: Transmembrane protein (Q57TW9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MYPQQQMSPPGNMQQWNAANSGYSMPYARPYSGYSNGTPPQQPQQPQQQVHMQMLPDAQMQQIPQQQMQQQPQQQMQMQQAPPQQFQQQQMQGDSNGQQPMWGYPPPNYQGYRGNPNMYDRRYSEAAAVPGCCNYERPGAASSGCCCTATEGTNPYCCGPPTEPGGPLNCCASMCDRTFVAMVFFFLLSTSAFATVMSLGDKDNILVKFKVPNTRALQAKINSNIVSSSGGCTDGFFTDSRLCMGDGIDAFALTVQLKTWSTQRNAMYFLAMIYSLFTLLYAYLINFHRRSNRGANDENDPLASSQHQHGGHQGSAMGYPSVKGQLDATINDSQQGSQNTQMQPGLQMSPRTGAADPIQVYGTPFYETMRCAWFVMGFAVVTWTYTLMASYMAQSQQYRDRASGELQQFLTAFHQRFIATVVCVTIYLAWPISNILIEIALWFVLIIPWLIYRTMCNPGLGNLRPDVPLDEMPGCIRLDMFFMDFADTRRLGFSDSQWRLLTGTGKPFFASCVDESTIDRDPSMPSLRYASNWAAGAQPGSYPQVPMNPGQMQPHGQQLQQQQQQQHVQQQLQQQQRMMQSSMTGDEAEGGEVHERSRRRRRDHSRRRGDRSHSRGGAETGETMEPSGFGTSPGRSVTGEDEGDIQADRGRRSRSRRRGHRDGSRNARSGDFNDWDDQSGGEGGRRHSRRGRSETNNSTMNSTGFLNPQDIDRMLNEV
Protein: Chronophage, isoform G (A8JV12)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFPGNMISPKVRGTNSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEA
Protein: Calcium-activated potassium channel subunit beta-2 (BK channel subunit beta-2) (BKbeta2) (Hbeta2) (Calcium-activated potassium channel, subfamily M subunit beta-2) (Charybdotoxin receptor subunit beta-2) (Hbeta3) (K(VCA)beta-2) (Maxi K channel subunit beta-2) (Slo-beta-2) (Q9Y691)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Calcium-activated potassium channel subunit alpha-1
- Calcium-activated potassium channel subunit beta-4
- Small conductance calcium-activated potassium channel protein 1
- Small conductance calcium-activated potassium channel protein 3
- Calcium-activated potassium channel subunit beta-1
- Intermediate conductance calcium-activated potassium channel protein 4
- Potassium channel subfamily U member 1
- Small conductance calcium-activated potassium channel protein 2
- Calcium-activated potassium channel subunit beta-3
- cGMP-dependent protein kinase 1
Sequence:
MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
Protein: Protein PROLINE CONTENT ALTERNATIVE 22 (F4IIS6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:28369480}.
Interaction partners:
- E3 ubiquitin-protein ligase RZF1
- Kinesin-like protein KIN-5A
- 3-ketoacyl-CoA synthase 12
- At5g11090
Sequence:
MNEEERVGSSSSSSSSLPVSYGVDCEKYDFSSSVSSLSQPFSPEGSSNKSHVLENNLSFVFSLDHNSNSSLMFPRDRPCSCLHHVFEWILQRCCGCLC
Protein: Adenosine deaminase (EC 3.5.4.4) (S-methyl-5'-thioadenosine deaminase) (EC 3.5.4.31) (A5KE01)
Organism: Plasmodium vivax (strain Salvador I)
Function: Catalyzes the hydrolytic deamination of adenosine to produce inosine. Unlike mammalian adenosine deaminases, also catalyzes the deamination of 5'-methylthioadenosine (MTA), a by-product of polyamine biosynthesis, to produce 5'-methylthioinosine (MTI). Plays an essential role in the purine salvage pathway which allows the parasite to use host cell purines for the synthesis of nucleic acids.
Interaction partners:
- IMP-specific 5'-nucleotidase 1
- Bifunctional dihydrofolate reductase-thymidylate synthase
- Inosine-5'-monophosphate dehydrogenase
- Lysine decarboxylase-like protein
- Adenylosuccinate synthetase
- GMP synthase
Sequence:
MNILQEPIDFLKKEELKNIDLSQMSKKERYKIWKRIPKCELHCHLDLCFSADFFVSCIRKYNLQPNLSDEEVLDYYLFAKGGKSLGEFVEKAIKVADIFHDYEVIEDLAKHAVFNKYKEGVVLMEFRYSPTFVAFKYNLDIELIHQAIVKGIKEVVELLDHKIHVALMCIGDTGHEAANIKASADFCLKHKADFVGFDHGGHEVDLKEYKEIFDYVRESGVPLSVHAGEDVTLPNLNTLYSAIQVLKVERIGHGIRVAESQELIDMVKEKNILLEVCPISNVLLKNAKSMDTHPIRQLYDAGVKVSVNSDDPGMFLTNINDDYEELYTHLNFTLEDFMKMNEWALEKSFMDSNIKDKIKNLYF
Protein: Adenylyl cyclase-associated protein 2 (CAP 2) (P52481)
Organism: Rattus norvegicus (Rat)
Function: May have a regulatory bifunctional role.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Drebrin
- Drebrin-like protein
- Profilin-4
- PH domain leucine-rich repeat protein phosphatase 1
- PH domain leucine-rich repeat-containing protein phosphatase 2
- Glutaredoxin domain-containing cysteine-rich protein 1
Sequence:
MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVAPSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQENEVAVLLKPISEKIQEIQTFRERNRGSDMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKIWSELQAYIKEHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEEPSPSRSALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGDDYREFPIPEQFKTIWDGSKLITEPAEIMA
Protein: Uncharacterized protein (Q582X9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQRLFFRSTCARVRCADLRLKPPVSIPQVTFQTVAFSSSAAGAAVRSGAEGTNTTTKRRSGFGGGAGGGGPVKDRYPPPATDLGDPRRRLAVLVDASSVDPRVFRNTILPAALKVGTPVLIRIFSVQLSSEWEPLVAGSGGTRESATSTEPEWKTSGTANDGREEVSGAAGSRDSGAWCPPVEFFRVERFIPVPMQMEADANHIFDFRKQNQIEAVAFVCGEVDRGVFEGFLPNIAGNGFNQYVLDELGMAKEVLEDGRSEDGTPTVQK
Protein: Translocase of chloroplast 125, chloroplastic (PpTOC125) (EC 3.6.5.-) (125 kDa chloroplast outer envelope protein) (A9SY64)
Organism: Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens)
Function: GTPase involved in protein precursor import into chloroplasts (Probable). Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis (Probable). Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast (Probable).
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Bacterial surface antigen
- Bacterial surface antigen
- Bacterial surface antigen
- Bacterial surface antigen
Sequence:
MDALRKLGSLGRRRDEVDTASSPLKNEASAAEIPRDPVQISGKDEASPSGLTPIRVRVPEDVRSESEVKRDGDEESVGSGESFDSALERMEASSITSFEPPSPMESIDGRFQFEDGVREDLAESGLDGNFSYDDDDDDEEEEEDGSEEGESTSSSIINSEYSSSASNTEDEMDISGYGASSARTMLVSNDASKSDEEAIDEPKYKLRNVVTGEENMSGGLSVENEARGVALSSWKSELEDFYEASLEDNDVQEELAEKIIKVASEQNDEEDEEVHFPVIANELPGRITRNRTMIDSPAHLYSAVKAVDSTLPALKSESTKSITQGFVEAEEAESDVFTEGEDGYDDEDEDGDIQMDVSQATEKSGTPDESESNPSMGAGGPRLPSLPQRSSARRSAATTATGVPRPNTASSTQSAATSDASISSESSEANEIREKLQNIRIKFLRLARRLNQSPQNVVVAQVLYRLGLAESLRGGSSLNRTRAFSFDHANALAEEQEAAKYEDLDFACTILVLGKTGVGKSATINSIFDECKTVTSAYYPSTTKVHEVSGTVLGVKVRFIDTPGLLPSTADQRHNKNIMRQVKKYIKKVSPDIVLYFDRMDMQTRDSGDVPLLRTITDVFGAAVWFNATVVLTHASKAPPDGSNGTPMSYDYFVAQRSHFVQQTIRQAAGDARLQNPVSLVENHPACRINRSGQRVLPNGQPWKQQLLLLCFASKILAEANTLLKLQEASTPGKPFGQRSRVPPLPYLLSSLLQSRAQLKMPDEQHGESEDSDDDSDEEDEEEGDEYDDLPPFRPLSKQELEDLSKEQRQEYAEELADRERLFQKKQYREQIRRRRERKKQASVMSKEEPSIPGDGAEDESGQPATVAVPMPDMALPPSFDSDNPTHRYRYLETANQWLVRPVLETHGWDHDAGYDGFNVEKMFVVKEKIPASVSGQVTKDKKEAQVNFEAAASLRHGEGKVTLTGFDVQTIGKDLAYTVRAETRFNNFKRNKTTAGVTATYLNDTIAAGVKLEDRVLIGKRVKLVVNGGVLTGKGDKAYGGSLEATLRGKEYPLSRTLSTLGLSVMDWHGDLAIGGNLQSQFMVGKTMMVGRANLNNRGSGQVSIRASSSEQLQMVLIGIVPILRSLINCRFGFGGQPQQ
Protein: Solute carrier family 4 member 11 (Sodium borate cotransporter 1) (NaBC1) (Q8NBS3)
Organism: Homo sapiens (Human)
Function: Multifunctional transporter with an impact in cell morphology and differentiation. In the presence of borate B(OH)4(-), acts as a voltage-dependent electrogenic Na(+)-coupled B(OH)4(-) cotransporter controlling boron homeostasis. At early stages of stem cell differentiation, participates in synergy with ITGA5-ITGB1 and ITGAV-ITGB3 integrins and BMPR1A to promote cell adhesion and contractility that drives differentiation toward osteogenic commitment while inhibiting adipogenesis (By similarity). In the absence of B(OH)4(-), acts as a Na(+)-coupled OH(-) or H(+) permeable channel with implications in cellular redox balance. Regulates the oxidative stress response in corneal endothelium by enhancing antioxidant defenses and protecting cells from reactive oxygen species. In response to hypo-osmotic challenge, also acts as water permeable channel at the basolateral cell membrane of corneal endothelial cells and facilitates transendothelial fluid reabsorption in the aqueous humor. In the presence of ammonia, acts as an electrogenic NH3/H(+) cotransporter and may play a role in ammonia transport and reabsorption in renal Henle's loop epithelium.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18024964, ECO:0000269|PubMed:25007886, ECO:0000269|PubMed:31273259}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:23813972}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Collagen alpha-2
- Cytosolic carboxypeptidase 4
- Lipoxygenase homology domain-containing protein 1
- Zinc finger E-box-binding homeobox 1
- Transcription factor 4
Sequence:
MAAATRRVFHLQPCENSPTMSQNGYFEDSSYYKCDTDDTFEAREEILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHLLSDTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP
Protein: Nuclear receptor subfamily 4 group A member 2 (F8W6I3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEEYEHRHFCLLLHCCPGYGHRETRAQGTQESGRTAKQDCKLSQRPRDFQQWGVEPPQLFVQTVGEAPRTSYPLHTGATAHFLPEIGRLGATASNN
Protein: Fanconi anemia group A protein (Protein FACA) (O15360)
Organism: Homo sapiens (Human)
Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Subcellular location: Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Interaction partners:
- Fanconi anemia group F protein
- Centromere protein S
- Centromere protein X
- Fanconi anemia group E protein
- Fanconi anemia group C protein
- Fanconi anemia group B protein
- Fanconi anemia group M protein
- Fanconi anemia core complex-associated protein 24
- FA core complex associated protein 20
- Fanconi anemia group I protein
Sequence:
MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLEAVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQMFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFGVFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYRRLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFESCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQQAAPDADLSQEPHLF
Protein: Protein Wnt-9a (Wnt-14) (O42280)
Organism: Gallus gallus (Chicken)
Function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a role in embryonic chondrocyte maturation and in embryonic bone mineralization (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:O14904}. Secreted {ECO:0000250|UniProtKB:O14904}.
Interaction partners:
- Wnt inhibitory factor 1
- Porcupine O-acyltransferase.
- Low-density lipoprotein receptor-related protein
- Notum, palmitoleoyl-protein carboxylesterase.
- Frizzled-2
- Secreted frizzled-related protein 2
- Cerberus
- Frizzled-1
- Secreted frizzled-related protein 1
- Frizzled-4
Sequence:
MALLRALLGLLACTPRPSAAYFGLTGNEALTILPLTSEMEEAAVKAHYKVCDRLKLEKKQRRMCRRDPGGAETLMEAISMSALECQYQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHAMAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSNKFVKEFLGRKPNKDLRARVDFHNNLVGMKVIKAGVETTCKCHGVSGSCTVRTCWRQLSPFHEIGKQLKQKYETSLKVGSTTNEATGEGDISPPKKSIPGHSDQIPRTTDLVYIDDSPSFCLMSRYSPGTSGRKCYKDKNCDSICCGRGHNTQSRVVTRPCQCQVRWCCYVECKQCTQREEVYTCKD