wanglab/gogpt-training-data huggingface dataset:
Protein: Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43) (Q13884)
Organism: Homo sapiens (Human)
Function: Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
Subcellular location: Cell membrane, sarcolemma {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions. {ECO:0000250}.
Interaction partners:
- Dystrophin
- Utrophin
- Gamma-2-syntrophin
- Dystrobrevin alpha
- Alpha-sarcoglycan
- Delta-sarcoglycan
- Gamma-sarcoglycan
- Beta-2-syntrophin
- Dystrobrevin beta
- Dystroglycan 1
Sequence:
MAVAAAAAAAGPAGAGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSSEEGAAAYNGIGTATNGSFCRGAGAGHPGAGGAQPPDSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDSATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTYPLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGFSITTEPQEGAFPKTIIQSPYEKLKMSSDDGIRMLYLDFGGKDGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA
Protein: Tropomodulin, isoform H (E1JJ21)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MAITDDATSATTKTTTLTTPAKLYGKDLSEYDDVDVESLLAQLSPEEITILAKEVDPDDNFLPPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEEIIDLAAILGFHSMMNQDQYHASLLNKGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRIRVKRLNQRK
Protein: Glycine receptor, alpha 4a (F1RDZ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection {ECO:0000256|ARBA:ARBA00004316}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
- Gephyrin
- Gephyrin
- G protein-coupled receptor, class C, group 5, member Bb
Sequence:
MLPQVIRILYVLSFFFFQGGFIRLGSCKEEIKSSSRPAQKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYSEYPDASLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRRQRIEEELVRESRGFYFRGYGLGHCLQTKDGTAVEGSSVFAPPPPVQVLYDGEAVRKRFVDRAKRIDTISRAVFPLSFLIFNVFYWITYKVLRHEDIHANP
Protein: Uncharacterized protein (Q869Z5)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Probable methionine--tRNA ligase, cytoplasmic
- Methionine synthase
Sequence:
MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK
Protein: Eukaryotic translation initiation factor 5 (H0YN40)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDSGTGKKEKEKKNRKGKDKENGSVSSSETPPPPPPPNEINPPPHTMEEEED
Protein: Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.-) (G3V167)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTL
Protein: Beta-glucosidase-like protein NCA3, mitochondrial (P46955)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase.
Subcellular location: Mitochondrion.
Interaction partners:
- Nuclear control of ATPase protein 2
- Mitochondrial translation factor ATP22
Sequence:
MKISAALILSSLSSVAFSAPAPAPADSHHEDHHKDEKPAVVTVTQYIDSNAATSTVESAATTTTLSSSEKDTSEQKRDGGFQDGTVKCSDFPSVNGIVSLDWLGFGGWASVMDMDANTSSECKDGYYCSYACEPGMSKTQWPSDQPSDGKSVGGLYCKNGYLYRTNTDTSDLCSTDETSAKAINKKSDSIALCRTDYPGSENMVIPTVVDGGDSQPISVVDEDTYYQWQGKKTSAQYYINNAGVSAEDGCIWGTSGSDVGNWAPLVLGAGSTNGETYLSLIPNPNSNQAANFNVKIVASDGANVQGSCAYEDGSFTGDGSDGCTVSVLSGSAEFVFY
Protein: Atlastin (EC 3.6.5.-) (Q9VC57)
Organism: Drosophila melanogaster (Fruit fly)
Function: GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate microtubule polymerization and Golgi biogenesis. Required for dopaminergic neurons survival and the growth of muscles and synapses at neuromuscular junctions.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19341724, ECO:0000269|PubMed:19633650}; Multi-pass membrane protein {ECO:0000269|PubMed:19341724, ECO:0000269|PubMed:19633650}. Golgi apparatus membrane {ECO:0000269|PubMed:19341724}; Multi-pass membrane protein {ECO:0000269|PubMed:19341724}. Note=Colocalizes with microtubules (PubMed:19341724).
Interaction partners:
- Spastin
- Receptor expression enhancing protein A, isoform I
- Reticulon-like protein
- Protein spartin
- Dynamin
- Acyl-coenzyme A diphosphatase FITM2
- Seipin
Sequence:
MGGSAVQVINASEEHTFVLNEDALSEVLMRDEVKDRFVCVVSVAGAFRKGKSFLLDFFLRYMYSKYVHHDATDWLGGESDPLEGFSWRGGSERDTTGILMWSDIFLHDYPNGDKIAIILLDTQGAFDSQSTVRDCATVFALSTMLSSVQIYNLSQNIQEDDLQHLQLFTEYGRLALADTGKKPFQRLQFLVRDWSFPYEAEYGALGGDKILKRRLEVSDKQHPELQSLRRHISSCFTEVACFLMPHPGLNVATNPKFDGRLQDITPEFKSSLRSLVPMLLAPDNLVYKEISGQRVRARDLIQYFQSYMNIYKGNELPEPKSMLVATAEANHLTAVAAAKELYGQLMEEVCGGTRPYLSTAHLQTEHLRVKDKALFQFAAKRKMGGEEFTEKFRKQLEDDLEEVFTNYQAHNESKNIFKAARTPAVYFACAVIMYILSGIFGLVGLYTFANFCNLVMGVALLTLALWAYIRYSGELSDFGGKLDDFATLLWEKFMRPIYHGCMEKGIHHVATHATEMAVGGGAASYRSQTSVNASNGKVKRS
Protein: glucan endo-1,3-beta-D-glucosidase (EC 3.2.1.39) (Q6FJK5)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
Sequence:
MFQLLTLLLPLVSKVSADCQMIAGNYYCSKTDAAIYSNVGFSGSYQDVTSMDEQSCVCSQQPFSFGGALAPFDEELSVHFRGPLKLSQFAVYYPASSNSKRAVAEEDCDSVVAKPVHKHKRDVAVEVIEVTETVFIDENGNTVTASGTSTSMSTPTPSNPSQVQSSQAPSQAPVSSSNKGTTTLSSTSKNTPSSSSSFQAASSSAAPIQDGGDWSRVAYFSPGTASGCTFMNHQGGTAGSGVWSSCFGNSISFANSDGVTGAGSPQPLGDVTIKSGQEYMIFSSTQCSANNAECGYYREGIPAYKGFGGNRKIFYFEFSMPSDTNGNGYNQDMPAIWLLNAKIPRTLQYGLSTCSCWATGCGELDLFEVLSPGSDKMITHIHDGQGGGTQDFFQRPTDGIFRAVVIFNASDKTIHLVQVDSAPAGGLSNDQVQQWLNKAGSAAALP
Protein: Protein translocase subunit SecF (Sec translocon accessory complex subunit SecF) (P0AG93)
Organism: Escherichia coli (strain K12)
Function: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. The large periplasmic domain is thought to have a base and head domain joined by a hinge; movement of the hinge may be coupled to both proton transport and protein export, with the head domain capturing substrate, and a conformational change preventing backward movement and driving forward movement. Expression of V.alginolyticus SecD and SecF in E.coli confers Na(+)-dependent protein export, strongly suggesting SecDF functions via cation-coupled protein translocation.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Sec translocon accessory complex subunit YajC
- Protein-export membrane protein SecG
- Protein translocase subunit SecY
- Protein translocase subunit SecD
- Membrane protein insertase YidC
- Protein translocase subunit SecE
- Protein translocase subunit SecA
- Protein-export protein SecB
- Queuine tRNA-ribosyltransferase
- S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Sequence:
MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP
Protein: Olfactory receptor (Q8R469)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
NPLRYPVVMSKAAYVPMAAGSWVSGSITATVQISLAMTLPFCGDNVINHFTCEILAVLKLACADISINVISMAVANAMFLGVPVLFIFVSYIFILSTILRIPSAEGRKKAFSTCSAHLTVVLVFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPML
Protein: Callose synthase 1 (EC 2.4.1.34) (1,3-beta-glucan synthase) (Protein GLUCAN SYNTHASE-LIKE 6) (Q9AUE0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in callose synthesis at the forming cell plate during cytokinesis. Not required for callose formation after wounding or pathogen attack. During plant growth and development, callose is found as a transitory component of the cell plate in dividing cells, is a major component of pollen mother cell walls and pollen tubes, and is found as a structural component of plasmodesmatal canals.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11283334, ECO:0000269|PubMed:11785931}; Multi-pass membrane protein {ECO:0000269|PubMed:11283334, ECO:0000269|PubMed:11785931}. Note=Localized in the forming cell plate during cytokinesis.
Interaction partners:
- Plasmodesmata-located protein 5
- UDP-glycosyltransferase 75B1-beta-D-glucosyl transferase 1)
- Glucan endo-1,3-beta-glucosidase 10
- Plasmodesmata-located protein 1
Sequence:
MAQRREPDPPPPQRRILRTQTVGSLGEAMLDSEVVPSSLVEIAPILRVANEVEASNPRVAYLCRFYAFEKAHRLDPTSSGRGVRQFKTALLQRLERENETTLAGRQKSDAREMQSFYQHYYKKYIQALLNAADKADRAQLTKAYQTAAVLFEVLKAVNQTEDVEVADEILETHNKVEEKTQIYVPYNILPLDPDSQNQAIMRLPEIQAAVAALRNTRGLPWTAGHKKKLDEDILDWLQSMFGFQKDNVLNQREHLILLLANVHIRQFPKPDQQPKLDDRALTIVMKKLFRNYKKWCKYLGRKSSLWLPTIQQEVQQRKLLYMGLYLLIWGEAANLRFMPECLCYIYHHMAFELYGMLAGSVSPMTGEHVKPAYGGEDEAFLQKVVTPIYQTISKEAKRSRGGKSKHSVWRNYDDLNEYFWSIRCFRLGWPMRADADFFCQTAEELRLERSEIKSNSGDRWMGKVNFVEIRSFWHIFRSFDRLWSFYILCLQAMIVIAWNGSGELSAIFQGDVFLKVLSVFITAAILKLAQAVLDIALSWKARHSMSLYVKLRYVMKVGAAAVWVVVMAVTYAYSWKNASGFSQTIKNWFGGHSHNSPSLFIVAILIYLSPNMLSALLFLFPFIRRYLERSDYKIMMLMMWWSQPRLYIGRGMHESALSLFKYTMFWIVLLISKLAFSYYAEIKPLVGPTKDIMRIHISVYSWHEFFPHAKNNLGVVIALWSPVILVYFMDTQIWYAIVSTLVGGLNGAFRRLGEIRTLGMLRSRFQSIPGAFNDCLVPQDNSDDTKKKRFRATFSRKFDQLPSSKDKEAARFAQMWNKIISSFREEDLISDREMELLLVPYWSDPDLDLIRWPPFLLASKIPIALDMAKDSNGKDRELKKRLAVDSYMTCAVRECYASFKNLINYLVVGEREGQVINDIFSKIDEHIEKETLITELNLSALPDLYGQFVRLIEYLLENREEDKDQIVIVLLNMLELVTRDIMEEEVPSLLETAHNGSYVKYDVMTPLHQQRKYFSQLRFPVYSQTEAWKEKIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMDMPPAPKIRNMLSFSVLTPYFSEDVLFSIFGLEQQNEDGVSILFYLQKIFPDEWTNFLERVKCGNEEELRAREDLEEELRLWASYRGQTLTKTVRGMMYYRKALELQAFLDMAKDEELLKGYKALELTSEEASKSGGSLWAQCQALADMKFTFVVSCQQYSIHKRSGDQRAKDILRLMTTYPSIRVAYIDEVEQTHKESYKGTEEKIYYSALVKAAPQTKPMDSSESVQTLDQLIYRIKLPGPAILGEGKPENQNHAIIFTRGEGLQTIDMNQDNYMEEAFKMRNLLQEFLEKHGGVRCPTILGLREHIFTGSVSSLAWFMSNQENSFVTIGQRVLASPLKVRFHYGHPDIFDRLFHLTRGGICKASKVINLSEDIFAGFNSTLREGNVTHHEYIQVGKGRDVGLNQISMFEAKIANGNGEQTLSRDLYRLGHRFDFFRMLSCYFTTIGFYFSTMLTVLTVYVFLYGRLYLVLSGLEEGLSSQRAFRNNKPLEAALASQSFVQIGFLMALPMMMEIGLERGFHNALIEFVLMQLQLASVFFTFQLGTKTHYYGRTLFHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKGIELMILLLVYQIFGQSYRGVVTYILITVSIWFMVVTWLFAPFLFNPSGFEWQKIVDDWTDWNKWIYNRGGIGVPPEKSWESWWEKELEHLRHSGVRGITLEIFLALRFFIFQYGLVYHLSTFKGKNQSFWVYGASWFVILFILLIVKGLGVGRRRFSTNFQLLFRIIKGLVFLTFVAILITFLALPLITIKDLFICMLAFMPTGWGMLLIAQACKPLIQQLGIWSSVRTLARGYEIVMGLLLFTPVAFLAWFPFVSEFQTRMLFNQAFSRGLQISRILGGQRKDRSSKNKE
Protein: Ciliogenesis-associated TTC17-interacting protein (M0RAU5)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in primary ciliogenesis by modulating actin polymerization.
Subcellular location: Nucleus {ECO:0000269|PubMed:24475127}. Cytoplasm {ECO:0000250|UniProtKB:Q7Z7H3}. Cell membrane {ECO:0000250|UniProtKB:Q7Z7H3}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q7Z7H3}. Note=Colocalized with TTC17 at F-actin rich zones and at dynamic plasma membrane protrusions. {ECO:0000250|UniProtKB:Q7Z7H3}.
Interaction partners:
Sequence:
MGDKAKGEGMVWGLEAGPGEASLCHTGLEDMLLFFPETLAILSDTGEPQGELTIEVQKGKYKDDLGILTHCLLVHASSRGFLDKSVCGSSLLGYLNEHLELMEQHSQEFIKFPIIPMERKMSVLKQDDQLVVSRSVKEGEETKTGVSVFPCKSLKGFVSSAANVVLLRVMAWRQSVPSGARFLALDSEGKLCYCTYKSLGFQTIQVGNQQAEMFIVEQTIHSEDGIPFSCQFYLLSDGHLAKRVQVGSPGCCIITKMPLIREEDVIEPPPTFDRKPLVWEEDLELYSKFLDRKEQLRLSHTRYLRQHPEAQALVSDFLLFLLLRRPEDVVTFAAEHFGPFAALRSPIPALRSSHQPSPFRSLEEEEEGEEEEEEEEEEEEGEEEGEGKEEVEEVEIEGDDDYLYVDEEEEVEDDIYYDSYYYKYEDENIYEDENIYYDNYDVDNDNDDIDNYDNDDDDDDDVDDDDDVKVDDDNVDVDNDNVDVDNDNI
Protein: Septin 12 (Q9D451)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Septin-4
- Septin-5
- Septin-6
- Septin-7
- Septin-8
- Septin-11
- Septin-2
- Neuronal-specific septin-3
- Septin-1
- Septin-10
Sequence:
MDERRSPSPCSSRPSSPRTPPNEMFGPVGIEAVLDQLRIKAMKTGFEFNIMVVGQSGLGKSTMVNTLFKSKVWQSTEPNLDVPMPQTLELHSVTHVIEEKGLKLKLTVTDTPGFGDQINNDKCWDPILSYINQQYEQYLQEELLITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLRRLCRTVNVVPVIARADSLTIEERDAFRSRIQQNLKTHCIDVYPQKCFDEDVNDRLLNSKIREQIPFAVVGADREHIVNGRCVLGRKTKWGIIEGKFGNIAGMQWVGGWKSGHTLHAWHPMHASPGVCPTWMATMTCKT
Protein: G protein-coupled purinergic receptor p2y 12 (P2Y purinoceptor 12) (Purinergic receptor P2Y12) (E7F2G6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Transmembrane protein 119a.
- Sal-like protein 1
- Macrophage colony-stimulating factor 1 receptor
- Olfactomedin-like protein 3A
- Macrosialin
- receptor protein-tyrosine kinase
- Interferon regulatory factor 8
Sequence:
MEQTTQLSFSNSSVSNSSSCSRDGALKTIVFPVLYSILLILGLSLNALAAWVFLRIPSKSHFIIYLKNIVVADIIMTLTFPFKILSDANVASVGIRIFVCRVSSVLFYLTMYISILFFGLISIDRCRKTMWPFVGTNPKRLLHRKLLSGVIWTSLLALSLPNVILTSRPNIGERFKCSDLKTELGLQWHEVVNHICQVIFWGNLIIVIICYTLISRELYKSYARTRSPRGTQSKKKHIQVNVFLVLAVFFICFVPFHFARVPYTISQTRALLFSCPQKLFFFKLKESTLWLSSLNSVLDPLIYFFLCKSFRSSLFNVMRLAPGRCRILRELGTDSAGDQQGNALT
Protein: Protein TANC1 (TPR domain, ankyrin-repeat and coiled-coil domain-containing protein 1) (Q6F6B3)
Organism: Rattus norvegicus (Rat)
Function: May be a scaffold component in the postsynaptic density.
Subcellular location: Postsynaptic density {ECO:0000269|PubMed:15673434}. Note=Largly colocalizes with SYP/synaptophysin, DLG1, DLG4 and GRIA1 at synaptic sites.
Interaction partners:
- Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3
- Disks large homolog 4
Sequence:
MLKAVLKKSREGVKGSKKEAGGDFGSETPTLSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSHLTQSRANKKSPGPVRKPKYVESPRVPGDPVMIPFREGSKPAEPIETEAKVDNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRLDNCSPVAEEETTGSAESVLPKAESSAGDGPVPYSQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHSTAGARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFQQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQVASSSPSSSLKTSDPTHDLPGTPLLSPSSSTSALSAARTPPGPGTVDSQRPREDAVKYLASRVVAYHYCQADNTYTCLVPEFVHSIATLLCRSHQLAAYRDLLIREPQLQSMLNLRSCVQDPVAAFKRGILEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDHGDTLSSFITKIIPKFPPWLKLIVTVRADFQEIISTLPFVKLSLDDFPGNQDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSRLVLRNLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQKMEALSCFLIKKRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTVELGHHILKAHIFKGLSKKTGVSSSHPQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLTKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSAVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKLEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVQLLLDRGCDVNPNDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATFKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGPGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPTNQEIKRLLARVEEECKQLQRNQQQKQQAPLPAPPNDSDNDEEAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRPASPQSWAGISKSLRETVAQPGLVMQPTKQAQIVKTNQHLGSGQSSMRNSNTKVQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFSTGTGCGHFGDRLGPSQSLQLQRGESGTAYPLPSKVKAAERLLAHASVAVDMALPSQGGPVSCSDVRHPASLSSSGSSGSPSSSVKMSSSTSSLTSSSSVSDGFKAQGPDCRIRDRGTTQVQGGTAEHRPRNTPFMGIMDKIARFQQQVNPPSRSWHCPVTEGLLTNTATAAGLQTNSEKPALKPGGYCSQAKPCSVPPLGMGVHNGAQVKELEENKCQVPALCQDNRKTKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV
Protein: Peroxin-19 (Q8IP97)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Peroxisomal membrane protein PEX13
- Peroxisomal biogenesis factor 3
- T-complex protein 1 subunit delta
- Peroxin 11
- Peroxisomal membrane protein PEX14
- Peroxisomal membrane protein PEX16
- Peroxisome assembly protein 12
- RING-type E3 ubiquitin transferase
- ATP-binding cassette sub-family D member 3
- Peroxisomal targeting signal 1 receptor
Sequence:
MSEEKKNGDELNDLLDSALQDFDKSGAGDQKEPSASSDVATNAGPEGSEDPDAFFIEQAKVLADRMNTLFGGPDTPSGDIPPLPQDPDQIMAGFKKMAEAAALTLSGENSATDEDVSKYSDSISQALKGLQEGSENLAAPASENDIASMFGSLNLEGAGEGDGNMFLPFMEGMMQSLLSAEILLPSIRELLEKYPKYLEENDAKLSAEDKERYQKQMELYKVIEGHLQSEKTEDSAAVKREKFRVVLDDMRKLQDYGQPPPEILAETGGDLPFGDPTAGVAAGGPGPQCPTM
Protein: Decarbamoylnovobiocin carbamoyltransferase (EC 2.1.3.12) (Novobiocin biosynthesis protein N) (Q9L9F4)
Organism: Streptomyces niveus (Streptomyces spheroides)
Function: Carbamoyltransferase that mediates 3'-carbamoylation of the noviosyl ring to produce novobiocin, the final step in the novobiocin biosynthesis pathway. Novobiocincin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
Interaction partners:
Sequence:
MLILGLNGNVSAAGADVVPNLNELYMHDAAATLVRDGVLVAAVEEERLNRIKKTTKFPSNAIRECLAAAGAKPADVDAIAYYFPEDFFDDIFQQLYTEHPSVPTRYSREMILERLRVDLGWAAPPDILHYVPHHLAHAMSTYYRSGMREALVVVMDGAGERNCTTIYRSDGAELFEIASYPVPKSLGMFYLYGTRHLGYGFGDEYKVMGLAPYGDPSTYRDVFSTLYSLGPNGTYELIPRGGVVFRMTTILREHGLQPRRRGEPFTQAHMDFAASVQETTEQIAMHVIGYWARSTGLRNLAFGGGVAHNSTLNGRILTSGLFDEVFVHPASHDAGSSEGAALVVARERGERVWPLPRLTNASLGPDLGDVDSLERTLKSWSPLVDVERPDDIVEATAHLLAAGEAIGWAHGRSEFGPRALGNRSILADARPKENQTRINAMVKKRESFRPFAPVVTAEAAGDYFDLPETVGHHDFMSFVVQVRADRRELLGAVTHVDGSARVQVVTEETNPRFHRLVTRFGELTGTPVLLNTSFNNHAEPIVQSVDDVLTSYLTTSLDVLVIEDFVVRRRTELPLALEDFTIGFRPVTRLVRRLADVSAGRPGAPEVSHEIYLDHTSGPRATISAAMYELLTHADGVTPLGSLGIELTGELLTELYDLWQGRFVTVAPVGDGAGSAP
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (Q9VQR2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004443}; Matrix side {ECO:0000256|ARBA:ARBA00004443}.
Interaction partners:
- Probable NADH dehydrogenase iron-sulfur protein 7
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH dehydrogenase 23 kDa subunit
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial
- Acyl carrier protein, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase 13 kDa B subunit
Sequence:
MPEPRSPMASFAESVLNVIDGPITWFRESIVEPNQQKQNWYHQRFRRVPTIDQCYTDDAVCRFEADQQFRRDRMVDNEIVNILRQRFEDCTLYEAPDHMVKCRPLMDQYEKATENWFIKYGDLGGYANAKTAYMKQKHRLIWERRHGPVGSGMKEEAAH
Protein: Histone H3 (C1BGV2)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQESSEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Protein: Non-structural protein NS-S (NSs) (I4EPA3)
Organism: Puumala virus (strain Sotkamo/V-2969/81)
Function: Antagonizes host type-I IFN signaling pathway.
Subcellular location: Host cytoplasm, host perinuclear region {ECO:0000250|UniProtKB:P0DTK1}. Host cytoplasm {ECO:0000269|PubMed:33478127}.
Interaction partners:
Sequence:
MNSNLLLPDKNLRMQREQWKWTQMTLIKTHCKPGNKQCQHWRTNSQTTREGWQMLCPGKKWILNLLTRLGLNLMTTSRRDQALGMEMSLM
Protein: SHUGOSHIN 2 (AtSGO2) (Q0WTB8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Dispensable for both meiotic and mitotic cell cycle progression. Required with SGO1 for full protection of centromeric cohesion during anaphase I. Required to prevent precocious release of pericentromeric cohesins during meiosis. Acts redundantly to SGO1.
Interaction partners:
- Protein PATRONUS 2
- Protein PATRONUS 1
- Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform
- Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' alpha isoform
- Sister chromatid cohesion 1 protein 1
- Separase
- Separase
- Sister chromatid cohesion protein SCC4
Sequence:
MVLTEMSLDYSNRVLGSQKDNVKQMDKEETQQKENMLFSSQEYAAKLQKENMTLMKALAHRNKLVELSGIEIQKLRINLRSVQEKNLQLAQANSQMLAELNTNRDRLKDLQHELGCKNALLKVKKHLEEQVLPRTHHESKDKVSASASDGDCKSFQVHDIKHKDTKRKRTTRIKSSVSADVKPIPVNDSNSKANRKRRVSGVIDTTGIPEEICQTEDDIDKGVVSRGVNQDIDNVVNKKFVPDAANPVKESVHRKRQCTRRQSTRFDVQETKQTEKLLEMDGAKESKETASFSLRRRSARLRHEEAEPCKSLHEGDEVRETIKRRRVSLRLSARFDIQEPHVTETSNADDARSIVIEESAGSRSESVEPSESRHETKEITRKRSFSTRRQSTKGKSQTDEAIKEIATDPSLVNTIVQECDQETESKDKPKADENEGMTRRSSVGRPSRHAAEKVQSYREVSLRVKMRRKC
Protein: V-type proton ATPase subunit a (A0A1D8PPB0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- H
- V-type proton ATPase proteolipid subunit
- V-type proton ATPase subunit
- V-type proton ATPase subunit B
- V-type proton ATPase proteolipid subunit
- H
- V-type proton ATPase subunit D
- V-type proton ATPase subunit H
- V-type proton ATPase subunit F
- V-type proton ATPase subunit G
Sequence:
MSPIRLSENSVLSSNNESNEAIFRSAPMTLVQFYVTIELARDMVGVLGKLGNVQFRDLNSKLTPFQRTFITELRSIDGLVSQLDFLHSIMIKQNTIKSDLYVNLHADMKPLPTSSEIDNIKTRLSEFYERIKHLDQSYNNLDRKRLKFIENRCVLNSLNEFHRSNLVGGGYDDEHTEDADYDDNAALLNEQRNHSLEIGYEAHNLDDISFNSLAGTIARDKVPILRNILWRVLRGNLYFHDIALDDEFPATESSMDLVHKNVFIIFIHGDFLRTRVRKIIQSLDGILFDNATGGSVARNETLTEINGKIEDLNNVVQTTKDQLVTELMIFQELYPDYCYIVQREKLIYETLNKFDEDSTRRCLVGEGWIPTNDFDKIRLALRNLIRQKTRRDGSDRDSNESVNISESIATETSLFAIDDSDHELTGFEIEDEDEVGSLIAVVNELATNRTPPTFHKTNKFTAAFQSIIDAYGIATYQEVNPGLATIITFPFMFSIMFGDLGHGFIVFLMAIYLILNEVRFGAMRNRDEIFDMAFTGRYIILLMGVFSMYTGLIYNDIFSKSMAIFSSGWKYVIPENYDATKGATLVAEKIAGKVYPFGLDWAWHGTENNLLFTNSYKMKLSVLMGYTHMNYSLMFSLVNYLFFKSRVDIIGNFIPGFLFMQSIFGYLALTIVYKWSVDWFGSNRQPPGLLNMLINMFLSPGTIEEPLYAGQKYIQVFLVLVAAVCVPWLLIYKPLVLKKQNDRAIQLGYSDLRSQRQHSLQLHEEEQALAMHDQGLNRDPPDDSFELLRGSDEEEQEFRFPNDVEPMFPSAGGHGGDDEDGFNFGDIVIHQVIHTIEFCLNCVSHTASYLRLWALSLAHAQLSTVLWSMTIQNAFGKTGTVGVIMTVVLFAMWFSLTVCILVFMEGTSAMLHSLRLHWVEAMSKFFQGEGYAYEPFTFKSIDI
Protein: Xaa-Arg dipeptidase (EC 3.4.13.4) (Beta-Ala-Lys dipeptidase) (Q8IYS1)
Organism: Homo sapiens (Human)
Function: Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus. Postulated to function in a metabolite repair mechanism by eliminating alternate dipeptide by-products formed during carnosine synthesis.
Interaction partners:
Sequence:
MRPGGERPVEGGACNGRSELELLKLRSAECIDEAAERLGALSRAIWSQPELAYEEHHAHRVLTHFFEREPPAASWAVQPHYQLPTAFRAEWEPPEARAPSATPRPLHLGFLCEYDALPGIGHACGHNLIAEVGAAAALGVRGALEGLPRPPPPVKVVVLGTPAEEDGGGKIDLIEAGAFTNLDVVFMAHPSQENAAYLPDMAEHDVTVKYYGKASHSASYPWEGLNALDAAVLAYNNLSVFRQQMKPTWRVHGIIKNGGVKPNIIPSYSELIYYFRAPSMKELQVLTKKAEDCFRAAALASGCTVEIKGGAHDYYNVLPNKSLWKAYMENGRKLGIEFISEDTMLNGPSGSTDFGNVSFVVPGIHPYFHIGSNALNHTEQYTEAAGSQEAQFYTLRTAKALAMTALDVIFKPELLEGIREDFKLKLQEEQFVNAVE