wanglab/gogpt-training-data huggingface dataset:
Protein: SET domain-containing protein (G8JY06)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEYSEAKVIEEQYSNDEEIGSYMYFFEHNNKKWCIDATKESPWKGRLINHSVLRPNLKTKVVEIDGSHHLILVARRQIAQGEELLYDYGDRSAETIAKNPWLVNT
Protein: Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) (Q15116)
Organism: Homo sapiens (Human)
Function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2. Following T-cell receptor (TCR) engagement, PDCD1 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation (By similarity). Suppresses T-cell activation through the recruitment of PTPN11/SHP-2: following ligand-binding, PDCD1 is phosphorylated within the ITSM motif, leading to the recruitment of the protein tyrosine phosphatase PTPN11/SHP-2 that mediates dephosphorylation of key TCR proximal signaling molecules, such as ZAP70, PRKCQ/PKCtheta and CD247/CD3zeta (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:30487606}; Single-pass type I membrane protein.
Interaction partners:
- Programmed cell death 1 ligand 1
- Programmed cell death 1 ligand 2
- Tyrosine-protein phosphatase non-receptor type 11
- T-lymphocyte activation antigen CD80
- T-lymphocyte activation antigen CD86
- Cytotoxic T-lymphocyte protein 4
- Galectin-9
- Tyrosine-protein phosphatase non-receptor type 6
- T-cell surface glycoprotein CD4
- Lymphocyte activation gene 3 protein
Sequence:
MQIPQAPWPVVWAVLQLGWRPGWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQTLVVGVVGGLLGSLVLLVWVLAVICSRAARGTIGARRTGQPLKEDPSAVPVFSVDYGELDFQWREKTPEPPVPCVPEQTEYATIVFPSGMGTSSPARRGSADGPRSAQPLRPEDGHCSWPL
Protein: Fimbrin (LD05347p) (O61604)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MATLNKFTKTLSIDEKAEIKEKFIELDANKDGFIDLHELKDALNQVGFKLAGYQVREMIDEYKGKQLTAFQGKLNLEEFEALCLDLKSKDVASTFKTVVSKKENLETLGGMSSISSEGTTHSVRLEEQLAFSDWINSNLGHDKDLQHLLPIDSEGKRLYLSIKDGILLCKIINHSCPDTIDERAINKKNLTVYREFENLTLALVSSQAIGCNIVNIDAHDLAKGKPHLVLGLLWQIIRIGLFSHITLDSCPGLAGLLFDNERLEDLMKMSPEAILLRWVNHHLERAGISRRCTNFQSDIVDSEIYSHLLKQIAGNDADVNLDALRESDLQSRAEIMLQQAAKLNCRSFLTPQDVVNGVYKLNLAFVANLFNNHPGLDKPEQIEGLESIEETREEKTYRNWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWSRVHKRFSPLRKFMEKLENCNYAVDLGKQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPIIEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQEDNLANAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMMALDYVPNMDSVDQNNHNSSANNSN
Protein: Anaphase-promoting complex subunit CDC16 (Cell division control protein 16) (P09798)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit MND2
- Anaphase-promoting complex subunit 1
- Anaphase-promoting complex subunit DOC1
- Anaphase-promoting complex subunit SWM1
- Anaphase-promoting complex subunit 9
- Anaphase-promoting complex subunit CDC27
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
Sequence:
MKFCLYCCHCYIVICGKATHYYKSSKATSNLKSSNRVLMRNPMSPSEQHSQHNSTLAASPFVSNVSAARTQQSLPTDAQNDRLQQPWNRTNTATSPYQSLANSPLIQKLQANIMTPHQPSANSNSNSNSITGNVVNDNNLLASMSKNSMFGSTIPSTLRKVSLQREYKDSVDGVVRDEDNDEDVHNNGDAAANANNDRESKLGHNGPLTTTTLTTTTTATQLDVSELSAIERLRLWRFDALMQHMYRTAEYIADKVYNISNDPDDAFWLGQVYYNNNQYVRAVELITRNNLDGVNILCRYLLGLSFVKLQRFDDALDVIGEYNPFSEDPSTTAANTMSNNGNNSNTSQPVTDGGIKMESSLCFLRGKIYFAQNNFNKARDAFREAILVDIKNFEAFEMLLSKNLLTPQEEWDLFDSLDFKEFGEDKEIMKNLYKINLSKYINTEDITKSNEILAKDYKLADNVDVVRSKVDICYTQCKFNECLELCETVLENDEFNTNILPAYIGCLYELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSLDRISEAQKYYSKSSILDPSFAAAWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLFLGMQFMAMNSLNLAESYFVLAYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVKDLDPSSRTTISIQLNLGHTYRKLNENEIAIKCFRCVLEKNDKNSEIHCSLGYLYLKTKKLQKAIDHLHKSLYLKPNNSSATALLKNALELNVTLSLDASHPLIDKSNLMSQASKDKASLNKKRSSLTYDPVNMAKRLRTQKEIFDQNNKALRKGGHDSKTGSNNADDDFDADMELE
Protein: Calmodulin-1 (P0DP33)
Organism: Xenopus laevis (African clawed frog)
Function: Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.
Interaction partners:
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
Protein: Uncharacterized protein TP_0183 (O83213)
Organism: Treponema pallidum (strain Nichols)
Interaction partners:
- Chromosomal replication initiator protein DnaA
- SsrA-binding protein
- Nuclease SbcCD subunit D
Sequence:
MKKGVRSSRLLILFVLFAHAVHAAPRVGVYRLEVSGVPAHTETTINDALFSFIRELRGYHVVDCREQAVPHRFPEKGNLDYIFCGAMDLTPEGIRLAVALKGKDHNATRLLSKTYETAARILLDSRHLVRDVFDRSVPLTGNQTETSSMRHTRAGEESVSSLDALAGSWHSTEEGERIVIVSEGRGIAVLRSGLSVPLKLKISDGVLVVSQKGAVNARQFSHFPPEIAQKLAQEARPLQWRFPKISGNNRLSGVRTAPVVRGAGHTASVEYEEVPEEWVRN
Protein: Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60) (Q8C761)
Organism: Mus musculus (Mouse)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I1 plays a major role in retrograde ciliary protein trafficking in cilia and flagella. Requires also to maintain a functional transition zone.
Subcellular location: Cell projection, cilium {ECO:0000250|UniProtKB:Q8WVS4}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8WVS4}. Note=Located at the base of the primary cilium in serum-starved fibroblasts. {ECO:0000250|UniProtKB:Q8WVS4}.
Interaction partners:
- Cytoplasmic dynein 2 intermediate chain 2
- Cytoplasmic dynein 2 light intermediate chain 1
- Cytoplasmic dynein 2 heavy chain 1
- Dynein light chain roadblock-type 1
- Dynein light chain Tctex-type protein 2B
- Dynein light chain 1, cytoplasmic
- Dynein light chain
- Dynein light chain roadblock-type 2
- Dynein light chain 2, cytoplasmic
- Dynein light chain Tctex-type 3
Sequence:
MEPGKRRTKDDTWKADDLRKHLKVQSGSPKEEKKLREKKAHKDSESAAPEYREHKSRDPDREARHKEKTAERDLYTSTEHPRGERDRERHKERRKDAKDREKDKLKERHRDQEAEKAHSRGKDREREKDRRARKEEIRQSMAYHDLLSRDMRGRQMAEKVEKKASKIRTEERERRDEDSERIDEDRERRYRERKLQYGDSKEHPLSYWLYKEDGEKKHRKAKDADREKRLREKSSMREKRERHAREKGSSLSDREVEDRHREKRHKEGLHYDDERRRSHADKKERSSKEEHKKRELKELEKEDNDLEATGPDEYLPNLEDDFVDYEDDFEVCDGDDDSNNEHEAREKAEELPLAQKREIQEIQKAISAENERVGELSLKMFQKQGWTEYTKEPWTDANDSPSRTPVCGIFVDFATASHRQKSRSQALKQKTRSSKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQYNEDNVERDIQTEDIETREVWTQHPGEGTAVSGGSEEKDFSDVTVVPKIDTPRLANFLRAACQVVAVLLEEDRLAAGPSWIPRAQDKALNISDSSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVHDLPEKAFAPSLDSRHLLCVWDIWQPSGPQKVLICESKVTCCCFSPLKAFLLFAGTVHGSVVVWDLREDSRIHHYVRLSNCFWAFRTPTFSTDGILTSVNHRSPLQAIEPVATSAYKKQSFVLSPFSTQEEMAGLSFHIASLDETGVLNVWVVVELPKADISGSMSDLGLIPGGRIKLVHSTVIQLGNSLSHKDSELWGSTQTLSVKFLPSDPNHFVVGTDMGLISHSTRQDWRVSPRVFKPEQHGVRPIKVNVIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGHAVTSLQWSPTRPAVFLVQDDASRIYVWDLLENDLGPVAQQPISPDKLVAMTIVGEPEKTSGSFVALVLARTSGTVDVQNLKRRWTTPAVDEHSQLRLLLQK
Protein: F420H(2)-dependent quinone reductase Rv1261c (Fqr) (EC 1.1.98.-) (P9WP13)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in a F420-dependent anti-oxidant mechanism that protects M.tuberculosis against oxidative stress and bactericidal agents. Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the one-electron reduction pathway. In vitro, catalyzes the reduction of menadione to menadiol; since menaquinone is the sole quinone electron carrier in the respiratory chain in M.tuberculosis, the physiological electron acceptor for Fqr-mediated F420H(2) oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M.tuberculosis.
Subcellular location: Cell membrane; Peripheral membrane protein {ECO:0000269|PubMed:16000731}.
Interaction partners:
- Uncharacterized HIT-like protein Rv1262c
- F420-dependent glucose-6-phosphate dehydrogenase
- Bifunctional F420 biosynthesis protein FbiB
- Phosphoenolpyruvate guanylyltransferase
- Putative coenzyme F420-dependent oxidoreductase Rv3520c
- Possible oxidoreductase
- Phosphoenolpyruvate transferase
- Hypothetical oxidoreductase
- F420-dependent hydroxymycolic acid dehydrogenase
Sequence:
MDISRWLERHVGVQLLRLHDAIYRGTNGRIGHRIPGAPPSLLLHTTGAKTSQPRTTSLTYARDGDAYLIVASKGGDPRSPGWYHNLKANPDVEINVGPKRFGVTAKPVQPHDPDYARLWQIVNENNANRYTNYQSRTSRPIPVVVLTRR
Protein: Protein NRT1/ PTR FAMILY 8.3 (AtNPF8.3) (Histidine-transporting protein) (Peptide transporter PTR2) (P46032)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Peptide transporter. Mediates the transport of di- and tripeptides. High affinity, low capacity transporter. Can also transport histidine.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:17151019}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGSIEEEARPLIEEGLILQEVKLYAEDGSVDFNGNPPLKEKTGNWKACPFILGNECCERLAYYGIAGNLITYLTTKLHQGNVSAATNVTTWQGTCYLTPLIGAVLADAYWGRYWTIACFSGIYFIGMSALTLSASVPALKPAECIGDFCPSATPAQYAMFFGGLYLIALGTGGIKPCVSSFGADQFDDTDSRERVRKASFFNWFYFSINIGALVSSSLLVWIQENRGWGLGFGIPTVFMGLAIASFFFGTPLYRFQKPGGSPITRISQVVVASFRKSSVKVPEDATLLYETQDKNSAIAGSRKIEHTDDCQYLDKAAVISEEESKSGDYSNSWRLCTVTQVEELKILIRMFPIWASGIIFSAVYAQMSTMFVQQGRAMNCKIGSFQLPPAALGTFDTASVIIWVPLYDRFIVPLARKFTGVDKGFTEIQRMGIGLFVSVLCMAAAAIVEIIRLHMANDLGLVESGAPVPISVLWQIPQYFILGAAEVFYFIGQLEFFYDQSPDAMRSLCSALALLTNALGNYLSSLILTLVTYFTTRNGQEGWISDNLNSGHLDYFFWLLAGLSLVNMAVYFFSAARYKQKKASS
Protein: Small ribosomal subunit protein mS31 (28S ribosomal protein S31, mitochondrial) (MRP-S31) (S31mt) (Imogen 38) (Q92665)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11279123}.
Interaction partners:
- Small ribosomal subunit protein mS39
- Small ribosomal subunit protein mS33
- Small ribosomal subunit protein mS22
- Small ribosomal subunit protein uS3m
- Small ribosomal subunit protein mS23
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein uS7m
Sequence:
MFPRVSTFLPLRPLSRHPLSSGSPETSAAAIMLLTVRHGTVRYRSSALLARTKNNIQRYFGTNSVICSKKDKQSVRTEETSKETSESQDSEKENTKKDLLGIIKGMKVELSTVNVRTTKPPKRRPLKSLEATLGRLRRATEYAPKKRIEPLSPELVAAASAVADSLPFDKQTTKSELLSQLQQHEEESRAQRDAKRPKISFSNIISDMKVARSATARVRSRPELRIQFDEGYDNYPGQEKTDDLKKRKNIFTGKRLNIFDMMAVTKEAPETDTSPSLWDVEFAKQLATVNEQPLQNGFEELIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLEKHLESFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKKDILKESNIQFN
Protein: CXXC finger protein 5 (D6RBE0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSSLGGGSQDAGGSSSSSTNGSGGSGSSGPKAGAADKSAVVAAAAPASVADDTPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGSGGGSMMGGESADKATAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLP
Protein: Superoxide dismutase [Fe] 1, chloroplastic (EC 1.15.1.1) (Protein FE SUPEROXIDE DISMUTASE 1) (FeSOD) (P21276)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15060130}. Plastid, chloroplast membrane. Plastid, chloroplast stroma.
Interaction partners:
- Superoxide dismutase 1
- Superoxide dismutase 2, chloroplastic
- Superoxide dismutase 3
- Superoxide dismutase 3, chloroplastic
- Superoxide dismutase 1, mitochondrial
- Superoxide dismutase 2, mitochondrial
- Superoxide dismutase 2, chloroplastic
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL46
- L-ascorbate peroxidase 1, cytosolic
Sequence:
MAASSAVTANYVLKPPPFALDALEPHMSKQTLEFHWGKHHRAYVDNLKKQVLGTELEGKPLEHIIHSTYNNGDLLPAFNNAAQAWNHEFFWESMKPGGGGKPSGELLALLERDFTSYEKFYEEFNAAAATQFGAGWAWLAYSNEKLKVVKTPNAVNPLVLGSFPLLTIDVWEHAYYLDFQNRRPDYIKTFMTNLVSWEAVSARLEAAKAASA
Protein: Uncharacterized protein (Q57ZS6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- 50S ribosomal protein L14, putative
- Uncharacterized protein
- Acyl carrier protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- tRNA/rRNA methyltransferase SpoU type domain-containing protein
- Kinetoplast ribosomal PPR-repeat containing protein 3
Sequence:
MKSVFDIARSHVTFPVSRDGTALRRVLKDWLDYTECQSLQAKPAFPAELCITVHPSVKSMSRVYTQGDPKMSGEVCRRPGEAASLSYTKRVRLLLWSAVLPWEVQRGLSMSVLEPPGNGGSVLGEVGVRHGLGGSGGAVDGGSAVATKGWKEVEDSLGVVTDPTTGTAADFVSGPQCSTLGASIIPGMLFVMSPESAAQGLCFWSGAIRQPIDIAFIAPVEPPAADTPSFSELRQRRLQLSLEGYDISRFFPDGELESPTVTFAVQSHSYLDPFPDCEQRDQQVGCGSSRERNKGIEDSRRYTATPEGVGRGNENVRYVLETRRNLLRDSIRSALRECRCTHGGVVWASNTGCAADGNPTGTGECDVEVTISLTLSDELKEDLREKARLYTNYVVPLEGHVRRHIKCLSGISPHPKGDATDGSDALQQKGTEAVWGEEGCVCTNGSAPFVAPPPIIKPPLPVKVGTLASTRPRSPMLADEAEGRSTRLAPSVFGKHDAPALQRAQQECNQLISASALARIPNTSPRAPEIPPIDYEIFDLCLRLGLCQSEAIYYFYGRIMREWSKELRRLRAAKSHGEGGVNDGNDMVLREEDVHRMLRLVHDPSLQVPPELSACVEAVASLRKITNEVGVPVV
Protein: Mitochondrial intermediate peptidase, mitochondrial (EC 3.4.24.-) (AtOCT1) (F4KDA5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Aminopeptidase which cleaves preproteins, imported into the mitochondrion, to their mature size. Could cleave both preproteins and preprotein intermediates already cleaved by the mitochondrial processing peptidase (MPP).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25732537, ECO:0000269|PubMed:28936218}.
Interaction partners:
- Intermediate cleaving peptidase 55, mitochondrial
- Mitochondrial inner membrane protease ATP23
- Mitochondrial ATP-independent inner membrane protease subunit 2
- Mitochondrial inner membrane protease subunit 2
- Probable mitochondrial-processing peptidase subunit beta, mitochondrial
- NADH dehydrogenase iron-sulfur protein 6
- Mitochondrial metalloendopeptidase OMA1
- Mitochondrial ATP-independent inner membrane protease subunit 1a
- Peptidase S24/S26A/S26B/S26C family protein
- Frataxin, mitochondrial
Sequence:
MWKLTRRLQPHINSTRWLVRNFRNGGAGDATGLYGFDHLKTAKGFQRFVADAIERSGELVSYISGMPSSPEIIKAMDEISDTVCCVVDSAELCRQTHPDREFVEEANKAAIEMNDYLHHLNTNHTLYAAVKKAEQDSNLLTKEASRTAHHLRMDFERGGIHLDPEKLDKVNNLTTNIFQLCREFSENIADDPGHVDIFPGSRIPRHLHHLLNPTYRSTSGGSRGSTRSAHKSKQKGFRINTDPRTVSSILQWTSDEEVRKMVYIQGNSVPHANHGVLEKLIAARHELSQMMGCNSYADIMVEPNLAKSPKVVTSFLQELSKTVKPKADEEFIAIRDFKREKCGNPSAELEPWDETYYTSMMKSSINDVDTAVVASYFPLPQCIEGLKVLVESLFGATFHTIPLAPGESWHPNVVKLSLHHPDEGDLGYLYLDLYSRKGKYPGCASFAIRGGRKISETEYQLPVIALVCNFSRACDSSIVKLNHSEVEVLFHEFGHALHSLLSRTDYQHFSGTRVALDLAEMPSNLFEYYAWDYRLLKRFARHYSTGETIPEKLVNSLQGARNMFAATEMQRQVFYALIDQMLFGEQPETARDVSHLVAELKRQHTSWNHVEGTHWYIRFSHLLNYGAGYYSYLYAKCFASTIWQSICEEDPLSLNTGTLLREKFFKHGGAKDPAELLTDLAGKEIISVHGEGIVPATTYLLNELRL
Protein: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 7.1.1.2) (Q9FNN5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250, ECO:0000305|PubMed:25732537}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13-B
- NADH dehydrogenase 1 alpha subcomplex subunit 8-A
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 9
- Probable NADH dehydrogenase 1 alpha subcomplex subunit 5
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase iron-sulfur protein 2
- NADH dehydrogenase iron-sulfur protein 6
Sequence:
MAPVRGILGLQRAVSIWKESNRLTPALRSFSTQAASTSTTPQPPPPPPPPEKTHFGGLKDEDRIFTNLYGLHDPFLKGAMKRGDWHRTKDLVLKGTDWIVNEMKKSGLRGRGGAGFPSGLKWSFMPKVSDGRPSYLVVNADESEPGTCKDREIMRHDPHKLLEGCLIAGVGMRASAAYIYIRGEYVNERLNLEKARREAYAAGLLGKNACGSGYDFEVYIHFGAGAYICGEETALLESLEGKQGKPRLKPPFPANAGLYGCPTTVTNVETVAVSPTILRRGPEWFSSFGRKNNAGTKLFCISGHVNKPCTVEEEMSIPLKELIERHCGGVRGGWDNLLAIIPGGSSVPLIPKNICEDVLMDFDALKAVQSGLGTAAVIVMDKSTDVVDAIARLSYFYKHESCGQCTPCREGTGWLWMIMERMKVGNAKLEEIDMLQEVTKQIEGHTICALGDAAAWPVQGLIRHFRPELERRIRERAERELLQAAA
Protein: N-sulfoglucosamine sulfohydrolase (Q3URR4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
TILLVLGLCGAHSRNVLLIVADDGGFESGVYNNTAIATPHLDALSRHSLIFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVQSLPLLLNQAGVRTGIIGKKHVGPETVYPFDFAFTEENSSVMQVGRNITRIKQLVQKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGYIPDWTPQIYDPQDVMVPYFVPDTPAARADLAAQYTTIGRMDQGVGLVLQELRGAGVLNDTLIIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPQRWGQVSDAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIQLTGRSLLPALEAEPLWATVFSSQSHHEVTMSYPMRSVYHQNFRLIHNLSFKMPFPIDQDFYVSPTFQDLLNRTTTGRPTGWYKDLHRYYYRERWELYDISRDPRETRNLAADPDLAQVLEMLKAQLVKWQWETHDPWVCAPDGVLEEKLTPQCRPLHNEL
Protein: Small nuclear RNA-activating complex, polypeptide 2 (snRNA-activating protein complex subunit 2) (E7F685)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Small nuclear RNA-activating complex, polypeptide 4
- Small nuclear RNA-activating complex, polypeptide 3.
- Small nuclear RNA-activating complex, polypeptide 1b
- Small nuclear RNA-activating complex, polypeptide 5
Sequence:
MKPPRRQRTVPSRFHKTPEQEQIDSARSLCKGWNRKDLHSFLQALKQQQDFESEIDLTEIQKKIPQRSLKQIENLINKVKLRVLQKVFKQVKSQRKKERKAKVPIETWGEMVQKISTSHGKTISAAFSQMLVVAATEPCSLMHSEPPHPVTQTPVFSRLYPAHTPNTTSRPTTSGVSPSSSVSTASAVSFIRPDSSSSAAGHIGKSDTVSSSLHQEPVMPEASTPTSSSSQSQSEAEAAVSSPVSSRPSPSTSSNKPSPISLELLGHDYPCKPRIMKSVVNFDKIYAYLSDMDSKTCSSALSSMECAVLLDLLMCLPEELPLLDCKGLQHHLLQLHSQLSKPTVKPESYSNGPLSGEANSSTSAQKPSAAAGSSEKHGPVKDSEDWASAGICPLNPLSVPVTLLKRKSVDCDK
Protein: Antisocial isoform 1 (GH15583p) (Rolling pebbles, isoform A) (Rolling pebbles, isoform D) (Q9VTS8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynapse {ECO:0000256|ARBA:ARBA00034110}.
Interaction partners:
Sequence:
MFPLTNRSSSGNRTNNNPSNNNNNQTTSFIIGGTTNINNNNNQLGGTNSAKDKGNFENNWSCNKTTGRRSGSGNSCSFLDLQSIRRLLEHDASGSVCPSCRISFDKGKRRKLIDTCGHERCYSCMFRNDQCPMCMNSSLKDVDGANAQGYDTGIGGSTSTIVSPLGSPQPQLRSHAQRNAALARYMQQHRQESQSPDYHHRYASNGKLPRAAALSTNGNGFTTGTTQTVTVDVHHQLGGGGGGAAAAAKQLMANGISGHSRSSSMSHNIHAAAYSELSAAPPAFATPPTRRRFFNHKNLRSALTGGSGGGSGVGGGVGGAGGVGGGHRRTASNGGCPIDTASILSGGSDAIDHHSSFLNEKLQKDQLHARLGLLLNDPGSNGNSSSSGSGCEPISAHSTTSTTSSSGVGAASTTTSGSSQNVSPEQTLASGAGMLSGSQLSVATSHGVKEDALSLCGKFKAGCSMLHVYEALPSKSRKGNVRRSTRGQQGSSSSASAASAVGSRVTASSLAAVQLALKPLFFEVPLQEPDPPYVGRQWLVQQLSNILLGTETRVVLINGQPGTGKTAFCLQLVEYSCFGRRQMQDDPDGIYSQLQLGAHCERMRGLASHMVGYHFCQADANLTCQVPDFVHSLAAQLCQAPQLTAYRDYLLSEPHLQDILSVRECIADAERVMKLAILEPLAHLHRAGKIPAKVAVIVVDALCEAEYHRPDHGHTIASFLAQLTPHFPAWLKLVATVRTQMLELVKAPSYTQLTLDSWASSQALQQDMLDYIGARLADSPEIRMNIGGGGGQNSQSGSQPQTKFVSHLQSLSRGSMLYAKLILDLIARGQLVIKSSSYKVLPVSLAQIFLLHFNLRFPTARSFEQAAPILNICLAALYPLTLDEIYYSMEALSHGREALSWPDFMQRFKLLDGFLIKRLDNTYMFFHSSLREWLMRRDEGESNKFLCDARLGHAGIAFRLSRLQAPLSPQLTLELGHHMLKAHLYGGTSLTLLSPRDLQSYWLAGAADNISSSLGALRNVYSPNLKVSRLVLLAGASPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGADVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRPHSQDVTRSVALQQALIGAAAQAHCKILEDLLDLNETEFDLDVNGMEPSSGELALTAAARHGCIDVVGILLSRGAQIDARNRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHIDVHGMRPLDRAIACRNIQAVQVFLRKGAKLGPTTWSMAMGKPEILVILLNKLLEDGNVLYRKNRFQEAAHRYQYALRKISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYYARAKARMELGALNEALVDANEAMQQAAQSGVLCEVVEVLKRIQTELLTRISISSEDQTGRMSNIGGGASVAYESHHEITDL
Protein: Big bang, isoform E (PDZ domain-containing protein BBG-LP29) (Q17Q84)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MYRLQRRTALITKQDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEADPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA
Protein: Polyhomeotic homolog 2 (A0A0A0MSI2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQMVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPVPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS
Protein: Hap41p (A0A1D8PM95)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Hap42p
Sequence:
MITATTSSTIATTTTSPEINHIVPQLEHNHKSSMASSNDTFSIAKTIASPTTTQPSLIVKASKDWVLPPRPKPGRKQKENTTTTTNKESKPKKKYVKKSQRKKELSSSLNSQQQQALHCHEDLSANIDDLPSLMKNISIIDSENMELKSHLLSLIHEYKHLKDIVFKQPIDMFSHNTTPISTTATTTTTTTPTASTTTTTTTTTSTSTTTPEVLSAISLQPSLSSVSSSNNNNQDDPLHQYSSIPSPGSPMSSISTPLPSTTNTNNNVTDGSVSTTTTTTSVGTPKSSIFANPLTILSGSTNVNVNVNGGVSRNTIHIPSILNLDSNVHKRSFDELSEFIDYSEGCSGSGSDGEGELISDLSRTTSSYSDQYLMNV