wanglab/gogpt-training-data huggingface dataset:
Protein: SWI/SNF and RSC complexes subunit arp9 (Actin-like protein arp9) (Actin-related protein 9) (Chromatin structure-remodeling complex subunit arp9) (Q9UTQ7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- SWI/SNF chromatin-remodeling complex subunit sol1
- Chromatin structure-remodeling complex subunit snf21
- SWI/SNF chromatin-remodeling complex subunit snf5
- Chromatin structure-remodeling complex subunit rsc7
- SWI/SNF global transcription activator complex subunit snf59
- Chromatin structure-remodeling complex subunit rsc1
- SWI/SNF chromatin-remodeling complex subunit snf22
- SWI/SNF and RSC complexes subunit ssr3
- Chromatin structure-remodeling complex subunit rsc9
- Chromatin structure-remodeling complex subunit rsc4
Sequence:
MPSFRDDHIIVIQTGSLYHRATFGLAESLEPPTIRVRTRVGKNDNGEYVFTNKEDINMEDPNVKTDETKVETSESTSEQPSNSNVTEEKNMGSSFHSECKVDDFTPLPNEIQPIQRGRVVDWEALKAFWKHLYSLLLKDPNDTTFRYPVCLVIPTYWSLYDRELATQFFFEECQVPGFTIAYEPLMGLYAIGILHGLVIDIGYEKTDITPILDGQIIFTATQQLPLGGRYMTQHLQNLLRESLPTLKSSGQYVSKEDITELFAEQVKCSEIAQVVRDEQDTAKDPVKALTSTNNVEEEDPAEDIGKIIASGQTRAYLAQKEREKNGESEKDEKPDNTDVEFQTIAIEPLGDCIVGRERFKICEPIFHRPSNETVSLPEAIYITIKNYAANYKRRNDLWENIIVLGCGSRIRGFRECLIQQLQFKYQLSGSLEPYYAAQGTDSILGMTTMPPTPYPALINPCKILPDYFPSWKPDAGTNAMFEELAFLGGSIVAKTSFNESVSSHYVTLEEYAQHGPTAIHTKQ
Protein: Protein SPMIP7 (Post-meiotic spermatogenesis protein 1) (Sperm microtubule inner protein 7) (Spermatogenesis-associated protein 48) (Q5NC83)
Organism: Mus musculus (Mouse)
Function: Essential for normal spermatogenesis.
Interaction partners:
- Zona pellucida-binding protein 1
- Fidgetin-like protein 1
- Fidgetin-like protein 2
Sequence:
MDMEVKTMPGKISIPRRFIFSEGKAIEHPDYPHYSNLLQKMNMPSVKGLEDRHNCVRFEKKCNPTFLKFHPYPPSVLPDYHLHYPYPPPYGRAYPLAPLRDDVPLGDPCSGFMSPGGDANLKPNIGRAIPNLVSFHDVKPQNRVPRPDKGFQTTIKRQTILAEELKQDRRWNSRKVPDISIKAKLGGWTSPMKVVPVPVHEHEVGTLSRIYTFDEEAISTDDSEPLVQLDKKYNIKDSFYKSSTQKAYEDVPWDKMLPPKLDPEETTVEKAADHISQCFSLKRYERLPAITQMVGGLWDRFQTRLFSAPAKPINFVSPSTRSKYIPLYTGHVQSTDADNVDNPYGDIKSVASPRHSKLQYTNSSRSANIPGYTGKVHFTATHPTNSNIPSREPSADSEMNRLLLQEMRVDRFRHQGPMSQMVTTVKPYNPFNKKEKETLEY
Protein: Im:7162391 (Nephrocystin-1) (Q08CL9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MPPKRRGPLQIVQRETDDIKRQVDALVQQAAKADVSENKEALQRCRELQRLVDDIMKRLKKLSKADEPAPVGNYDQCKREEEKRLLTLHDHLQSLALQLLPHDETAGPSSSHTEQDSEEEDSDEEDESSEEEDAKGDVHEEDDDADSADEDTDMAAAAEQGSASYITLSSFTAKEEGDLSIQKGEILKVLSKNKDGWWLAQNSNGQKGLVPKTFLKMSSSLQDSERENEDEEDSEEEQESSKTSNWNTVRKAVTEIDATDVLSAMGAIPPGFRPSTLSRLLEEGSSYRASHFIQPKLSQSQLSFKDLHMDPDTGKVHGRPSRVSLTLTLWSCRMIPSPGVGLQVLSRHVRLCAFNGTQVLSNIHTVRATYNSKNPKTWSFSPRMTGMLPCLLDGDCFLRCDSESSDLGILFELGVTYIRNSTGERGDLSCGWTFLKLFDESGAPIALRTQELTIHGGTPFEKDLDMDTMSTKKGYQTGVFHQMLLSRKMPKLVVKLKSLNSSSRSRLNLLPDTIVGSLSTLHLLATYRQILADALLLDRVTMCNADLICSSVLASFPNVLDQPDLMDAFRKSWSESESNLKRSEKRDINILKQMFVSVYMGSVFPLLFSAEMPTPCWADEETESQRARIIYNPSQKTSIETLLSSQNSHQAFDITQVTYDLISSARQ
Protein: Protein YhcC (P0ADW6)
Organism: Escherichia coli (strain K12)
Function: In vitro, can cleave S-adenosyl-L-methionine into methionine and 5'-deoxyadenosine (AdoH).
Interaction partners:
- Putative nuclease YhcG
- Uncharacterized protein YoeI
Sequence:
MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRGHDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE
Protein: Polygalacturonase ADPG2 (AtADPG2) (PG ADPG2) (EC 3.2.1.15) (Pectinase ADPG2) (Protein ARABIDOPSIS DEHISCENCE ZONE POLYGALACTURONASE 2) (Q8RY29)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Polygalacturonase involved in cell separation in the final stages of pod shatter, in anther dehiscence and in floral organ abscission.
Subcellular location: Secreted, cell wall {ECO:0000250}.
Interaction partners:
- Polygalacturonase 1 beta-like protein 2
- Dof zinc finger protein DOF4.7
- Polygalacturonase 1 beta-like protein 3
- Receptor-like protein kinase 5
- LRR receptor-like serine/threonine-protein kinase HSL2
- CASP-like protein 2A2
- Probable LRR receptor-like serine/threonine-protein kinase At4g36180
- GDSL esterase/lipase At5g03810
- Proline-rich family protein
- Plant invertase/pectin methylesterase inhibitor superfamily protein
Sequence:
MARCTNLVTVFLLWALLMFSWCKASRISPNVYDHSYKRFKSDSLIKRREDITGLRSFVRASLRTPTTVSVSDFGAKGDGKTDDTQAFVNAWKKACSSNGAVNLLVPKGNTYLLKSIQLTGPCNSILTVQIFGTLSASQKRSDYKDISKWIMFDGVNNLSVDGGDTGVVDGNGETWWQNSCKRNKAKPCTKAPTALTFYNSKSLIVKNLKVRNAQQIQISIEKCSNVQVSNVVVTAPADSPNTDGIHITNTQNIRVSESIIGTGDDCISIESGSQNVQINDITCGPGHGISIGSLGDDNSKAFVSGVTVDGAKLSGTDNGVRIKTYQGGSGTASNIIFQNIQMDNVKNPIIIDQDYCDKSKCTTEKSAVQVKNVVYRDISGTSASENAITFNCSKNYPCQGIVLDRVNIKGGKATCTNANVVDKGAVLPQCNST
Protein: DNA topoisomerase I (EC 5.6.2.1) (DNA topoisomerase 1) (Q4Q2K0)
Organism: Leishmania major
Interaction partners:
- DNA topoisomerase type IB small subunit
- DNA topoisomerase 2
- DNA topoisomerase 2
- DNA topoisomerase
- DNA topoisomerase
- Tyrosyl-DNA phosphodiesterase 1
- Putative small ubiquitin protein
- SUMO-conjugating enzyme UBC9
Sequence:
MKVENSKMEVKREQSYSNEDEEINEEDLNWWEQENLRIAMKGERRWETLAHNGVLFPPEYEPHGIPIFYDGREFKMTPEEEEVATMFAVMKEHDYYRMEVFRRNFFESWREILGKRQHPIRRLELCDFEPIYQWYLVQREKKLSRTKEEKKAIKEKQDAEAEPYRYCVWDGRREQVANFRVEPPGLFRGRGKHPLMGKLKVRVQPEDITINIGETAEVPVPPAGHKWAAVQHDHTVTWLAMWRDNVAGNMKYVMLAPSSSVKGQSDMVKFEKARKLKDKVDDIRASYMEAFKSNDLHVAQRAVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHIQLMPDNIVRFDFLGKDSIRYQNDVAVLPEVYALLQRFTCRKSPGMDIFDQLNPTQLNDHLKSFMDGLSAKVFRTYNASITLDRWFKEKPVDPKWSTADKLAYFNKANTEVAILCNHQKSVSKNFKLQMMQLTTKSEYTRKTLELLEKAEVTAKKKSVEEAAKEFLEEQDRMQREWLESYGTEEQKKEFEEIVAKRAAPRVRSEKKSSSGTKKAKSASGKTRAATKKKSAKKSGKASSKKAARKSSKKAPKRSKEEDEDDVPLMSMAAKTKKTAGVKRQRAVKVASDDDDVPLAALRV
Protein: Patellin-5 (Q9M0R2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Carrier protein that may be involved in membrane-trafficking events associated with cell plate formation during cytokinesis. Binds to some hydrophobic molecules such as phosphoinositides and promotes their transfer between the different cellular sites (By similarity).
Subcellular location: Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly membrane-associated. Also cytoplasmic (By similarity). {ECO:0000250}.
Interaction partners:
- AT1G14820 protein
- Two-component response regulator ARR22-like protein
- AT3g10210/F14P13_19
- SEC14 cytosolic factor family protein / phosphoglyceride transfer family protein
- Transmembrane protein
- Sec14p-like phosphatidylinositol transfer family protein
- Sec14p-like phosphatidylinositol transfer family protein
- Copper ion binding protein
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH14
- Appr-1-p processing enzyme family protein
Sequence:
MSQDSATTTPPPPLTSDVSMPSGEEDEPKHVTSEEEAPVTSETNLKLPLMPELEESNHTAEVVSEKVTPETMTLESEGLNHAAEDSEQTHEVTPETETAKLEVLNHTAEDSEQTHEVTPEKETVKSEFLNHVAEDSEQTHEVTPETETVKSEVLNHAAEDSEQPRGVTPTPETETSEADTSLLVTSETEEPNHAAEDYSETEPSQKLMLEQRRKYMEVEDWTEPELPDEAVLEAAASVPEPKQPEPQTPPPPPSTTTSTVASRSLAEMMNREEAEVEEKQKIQIPRSLGSFKEETNKISDLSETELNALQELRHLLQVSQDSSKTSIWGVPLLKDDRTDVVLLKFLRARDFKPQEAYSMLNKTLQWRIDFNIEELLDENLGDDLDKVVFMQGQDKENHPVCYNVYGEFQNKDLYQKTFSDEEKRERFLRWRIQFLEKSIRNLDFVAGGVSTICQVNDLKNSPGPGKTELRLATKQALHLLQDNYPEFVSKQIFINVPWWYLAFYRIISPFMSQRSKSKLVFAGPSRSAETLLKYISPEHVPVQYGGLSVDNCECNSDFTHDDIATEITVKPTTKQTVEIIVYEKCTIVWEIRVVGWEVSYGAEFVPENKEGYTVIIQKPRKMTAKNELVVSHSFKVGEVGRILLTVDNPTSTKKMLIYRFKVKPLACE
Protein: Casein kinase 1-like protein 6 (EC 2.7.11.1) (Plasmodesmal-associated protein kinase 1) (Protein CASEIN KINASE I-LIKE 6) (Q8LPJ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins (By similarity). Phosphorylates tubulins and microtubules in vitro. Involved in anisotropic cell growth and cell shape formation via the regulation of microtubule organization.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P48730}. Cell junction, plasmodesma {ECO:0000269|PubMed:16126836}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18945931, ECO:0000269|PubMed:19820321}. Endomembrane system {ECO:0000269|PubMed:19941015}. Cell junction {ECO:0000269|PubMed:19941015}. Note=Present in punctate particles with granular structure (PubMed:16126836, PubMed:18945931, PubMed:19820321, PubMed:19941015). Associates transiently with cortical microtubules. Shuttles between microtubules and punctate particles in a kinase activity-dependent manner (PubMed:18945931, PubMed:19820321). Localizes to motile vesicle-like structures (late endosomal-like compartments) found both in the cytoplasm and at the cell periphery, especially at the cellular junctions (PubMed:19941015). {ECO:0000269|PubMed:16126836, ECO:0000269|PubMed:18945931, ECO:0000269|PubMed:19820321, ECO:0000269|PubMed:19941015}.
Interaction partners:
- At3g49990
- Bystin
- Serine/threonine-protein kinase RIO2
Sequence:
MDLKMDNVIGGKFKLGRKIGGGSFGELFLAVSLQTGEEAAVKLEPAKTKHPQLHYESKIYMLLQGGSGIPSLKWFGVQGDYNAMVIDLLGPSLEDLFNYCNRRLTLKAVLMLADQLISRVEYMHSRGFLHRDIKPDNFLMGLGRKANQVYIIDFGLAKKYRDLQTHRHIPYRENKNLTGTARYASVNTHLGVEQSRRDDLESLGYVLMYFLRGSLPWQGLKAGTKKQKYDRISEKKVSTPIEVLCKSYPPEFVSYFQYCRSLRFEDKPDYSYLKRLFRDLFIREGYQFDYVFDWTALKHPQSSARSHSSTHERHRTGKPGMGAGPSAEKPERISVGNIRDKFSGAVEAFARRNVRGPSPHQNHTRHRTLDEIPSMKPAVNMVSEKGRNTSRYGSASRRAVASGSRPSSSGEQRESRDSSRVASSGGGVRPSVFQRTQAAAAVSGYESKTASAFNRDRVAASRTARDEALRSFELLSIRK
Protein: Inactive serine protease 45 (Inactive testis serine protease 5) (Q6IE62)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Galactosidase, beta 1-like
Sequence:
MATSLRLLDAGPGSLRRWIPTCFAALLLLPPRPNLGYNEDHAEPVCGAPWWSDSLEERHHWPWEVSLQIENEHVCGGALIDQSWVVSAAHCIQGNKEYLVMLGSSTLQPSGSPWALKIPVGDIIMHPKYWGQNFIRSDIALLCLETPVTFNKYIQPICLPEHNFNLKVGMKCWVTGWGQAKQHPSAKLTRSLELWEAEVSIVDNKNCDRVFHKKTFYPQVIPLIRKNMICTTNHRENPCYGDPGGPLACEVHGRWILAGIFSWEKACTKAPNLSVYTRIDKYTGWIKEQVSRGARSGRCRTSCLLFLPWLLQLPVSPGPPHPFLFLLCLC
Protein: Regulator of sigma-E protease RseP (EC 3.4.24.-) (S2P endopeptidase) (Site-2 protease RseP) (S2P protease RseP) (Site-2-type intramembrane protease) (P0AEH1)
Organism: Escherichia coli (strain K12)
Function: A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA, residue 'Val-148' of RseA may be required for this. This provides the cell with sigma-E (RpoE) activity through the proteolysis of RseA. Can also cleave sequences in transmembrane regions of other proteins (such as LacY) as well as liberated signal peptides of beta-lactamase, OmpF, LivK, SecM, PhoA, LivJ, OmpC, Lpp and TorA, probably within the membrane.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:11689431, ECO:0000269|PubMed:11750129, ECO:0000269|PubMed:11867724, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:11689431, ECO:0000269|PubMed:11750129, ECO:0000269|PubMed:11867724, ECO:0000269|PubMed:15919996}.
Interaction partners:
- Outer membrane protein assembly factor BamA
- Anti-sigma-E factor RseA
- Serine endoprotease DegS
- Sigma-E factor regulatory protein RseB
- Ditrans,polycis-undecaprenyl-diphosphate synthase
- Phosphatidate cytidylyltransferase
- Periplasmic serine endoprotease DegP
- ECF RNA polymerase sigma-E factor
- Chaperone protein Skp
- Outer membrane protein assembly factor BamB
Sequence:
MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGFGKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIAAGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETPDWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPRGPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEIERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKTWQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGIINLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
Protein: L-type lectin-domain containing receptor kinase IV.2 (Arabidopsis thaliana lectin-receptor kinase a4) (AthlecRK-a4) (LecRK-IV.2) (EC 2.7.11.1) (Protein SMALL, GLUED-TOGETHER, AND COLLAPSED POLLEN) (Q9M345)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required during pollen development.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9LSR8}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- DUF7650 domain-containing protein
- Two-pore potassium channel 2
- Large ribosomal subunit protein eL8z
- NADH-Ubiquinone/plastoquinone
- Nuclease
- Probable pectinesterase/pectinesterase inhibitor 21
- COBRA-like protein 7
Sequence:
MFVKLKLIFFFFLLCQIMISSSQNLNFTYNGFHPPLTDISLQGLATVTPNGLLKLTNTSVQKTGHAFCTERIRFKDSQNGNVSSFSTTFVFAIHSQIPTLSGHGIAFVVAPTLGLPFALPSQYIGLFNISNNGNDTNHIFAVEFDTIQSSEFGDPNDNHVGIDLNGLRSANYSTAGYRDDHDKFQNLSLISRKRIQVWIDYDNRSHRIDVTVAPFDSDKPRKPLVSYVRDLSSILLEDMYVGFSSATGSVLSEHFLVGWSFRLNGEAPMLSLSKLPKLPRFEPRRISEFYKIGMPLISLSLIFSIIFLAFYIVRRKKKYEEELDDWETEFGKNRFRFKELYHATKGFKEKDLLGSGGFGRVYRGILPTTKLEVAVKRVSHDSKQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTHVVGTLGYLAPEHSRTGRATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLRGDMALPELTPLDLSAGSVMNLGGRDGFSGIAMTDFSTVFKGFTGGSSIADSLLSGGR
Protein: Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Glutathione S-transferase LTC4) (EC 2.5.1.-) (Leukotriene-C(4) synthase) (Q60860)
Organism: Mus musculus (Mouse)
Function: Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 with high specificity. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions (By similarity).
Subcellular location: Nucleus outer membrane {ECO:0000250|UniProtKB:Q16873}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q16873}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q16873}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q16873}. Nucleus membrane {ECO:0000250|UniProtKB:Q16873}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q16873}.
Interaction partners:
- Leukotriene A-4 hydrolase
- Polyunsaturated fatty acid 5-lipoxygenase
- Glutathione hydrolase 5 proenzyme
- Glutathione hydrolase 1 proenzyme
- Cysteinyl leukotriene receptor 1
- Cysteinyl leukotriene receptor 2
Sequence:
MKDEVALLATVTLVGVLLQAYFSLQVISARRAFHVSPPLTSGPPEFERVFRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLFYLFARLRYFQGYARSAQLRLTPLYASARALWLLVAMAALGLLVHFLPGTLRTALFRWLQMLLPMA
Protein: Internal alternative NAD(P)H-ubiquinone oxidoreductase A1, mitochondrial (EC 1.6.5.9) (Internal alternative NADH dehydrogenase NDA1) (Internal non-phosphorylating NAD(P)H dehydrogenase 1) (StNDI1) (NADH:ubiquinone reductase (non-electrogenic) NDA1) (Q9ST63)
Organism: Solanum tuberosum (Potato)
Function: Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:10571867}; Peripheral membrane protein {ECO:0000269|PubMed:10571867}; Matrix side {ECO:0000269|PubMed:10571867}. Peroxisome {ECO:0000250}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
Sequence:
MPWFKNLIKISKTITNQSSSYKSITPLASPLLTQFLQFTKQYSTNDHVVGLEATKSDQKPRIVVLGSGWAGCRLMKDIDTNIYDVVCVSPRNHMVFTPLLASTCVGTLEFRSVAEPIGRIQPAVSTQPASYFFLANCNAIDFDNHMIECETVTEGVETLEAWKFNVSYDKLVIASGAHALTFGIKGVNEHATFLREVHHAQEIRRKLLLNLMLSDVPGVSEEEKRRLLHCVVVGGGPTGVEFSGELSDFILKDVHQRYAHVKDYIHVTLIEANEILSSFDDRLRVYATNQLTKSGVRLVRGLVQHVQPDNIILSDGTNVPYGLLVWSTGVGPSPFVNSLDIPKAKGRIGIDEWLRVPSVQDVYSIGDCSGFLESTGRQVLPALAQVAERQGKYLASLLNKVGKQGGGHANCAQNINLGDPFVYKHLGSMATIGRYKALVDLRESKEAKGVSLAGFTSFFVWRSAYLTRVVSWRNKIYVLINWLTTLVFGRDISRI
Protein: Putative hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 9) (RBBP-9) (O88851)
Organism: Mus musculus (Mouse)
Function: Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1.
Interaction partners:
- Protein phosphatase methylesterase 1
Sequence:
MASPNKAVIVPGNGGGDVATHGWYGWVKKGLEQIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHQVYALVLVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIVQFGSTDDPFLPWKEQQEVADRLDAKLYKFTDRGHFQNTEFHELISVVKSMLKGPE
Protein: Protein lgg (E2JKY9)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MDRCKFLVPEHITVAELMSIVRRRLQLHPQQAFFLLVNERSMVSNSMSMSNLYSQERDPDGFVYMVYTSQPAFG
Protein: Kunitz type trypsin inhibitor 106 (G7LCV1)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Protease inhibitor that, together with SCP1, controls mycorrhiza establishment and arbuscule development during root colonization by arbuscular mycorrhizal (AM) fungi (e.g. Rhizophagus irregularis), probably by degrading SCP1 in the apoplast of the periarbuscular region.
Subcellular location: Secreted {ECO:0000269|PubMed:23662629}. Secreted, extracellular space, apoplast {ECO:0000269|PubMed:23662629}.
Interaction partners:
Sequence:
MSMRLSIRTLIILAHVCLFITTTTIAQFVLDTVGEPVEGDEEYFIRPVITNKGGRSTMVSRNESCPLHVGLELTGLGRGLVVKFTPFAPHHDFDDVRVNRDLRITFQASSSCVQSTEWRLGEKDTKSGRRLIITGTDSATNGSYGNFFRIVETPLEGMYNIQWCPTEVCPSCKFECGTVDMLNENGKILLALDGGPLPLVFQKE
Protein: NB-ARC domain-containing protein (Q4GZE5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Guide RNA associated protein, GAP1
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- NADH dehydrogenase subunit NI8M
- NADH-ubiquinone oxidoreductase complex I subunit
- Uncharacterized protein
- Adrenodoxin reductase, putative
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase complex I subunit
Sequence:
MWRLLRRACVKKFPGGQTASTTFGCSVKRGATTIGMSDDPPAADPILFDAPVASRVVGREREIMQLWQNLLAGRHCQVIAGLDGIGKTTIAVEFCSRARRSGRFTCVHWFDWDDSLESHLLQFFQSMKGRKEKDVLLVVDGTPNPQVVLQLIPDHPNVYALVTSSADPVGNLKIPVLKAGSFTEVDADQFLQGINVEERATSSTRDVMHAVCRVPILMHLACCLMESGSVSPEELRSLLLAKGVGAEGTISVSHALNVFLDVALNELESHFPDGTKQLRTLAFFDARNIPYAVVDSVVGSERGEEFVMFLTGLGICGQRWEDSSLFIHSCIADALLTGADDAILLRSAEVLQALWPRRWRSAGSSTAHELVRHTTALLKWFNARKLSLSNDLLLGLDRSATFLALNEGKELRKAAEFWIRVVNSDQHADRRTTEAVRVGRECGRLLHFLRDQRASSVLQYAYHLGVAVYGQQSPEAALILGCYAPYLPSSHETVQLLCQSAAALKNRLGCAEAVLGREEERMLLETVFVLYMCQGQMLQELGELVPDSLWESLQSVEKELKGGKHSKLK
Protein: Tyrosine-protein phosphatase 69D (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (DPTP) (P16620)
Organism: Drosophila melanogaster (Fruit fly)
Function: Possible cell adhesion receptor.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Liprin-alpha, isoform E
- Tyrosine-protein phosphatase 99A
- Tyrosine-protein phosphatase 10D
Sequence:
MALLYRRMSMLLNIILAYIFLCAICVQGSVKQEWAEIGKNVSLECASENEAVAWKLGNQTINKNHTRYKIRTEPLKSNDDGSENNDSQDFIKYKNVLALLDVNIKDSGNYTCTAQTGQNHSTEFQVRPYLPSKVLQSTPDRIKRKIKQDVMLYCLIEMYPQNETTNRNLKWLKDGSQFEFLDTFSSISKLNDTHLNFTLEFTEVYKKENGTYKCTVFDDTGLEITSKEITLFVMEVPQVSIDFAKAVGANKIYLNWTVNDGNDPIQKFFITLQEAGTPTFTYHKDFINGSHTSYILDHFKPNTTYFLRIVGKNSIGNGQPTQYPQGITTLSYDPIFIPKVETTGSTASTITIGWNPPPPDLIDYIQYYELIVSESGEVPKVIEEAIYQQNSRNLPYMFDKLKTATDYEFRVRACSDLTKTCGPWSENVNGTTMDGVATKPTNLSIQCHHDNVTRGNSIAINWDVPKTPNGKVVSYLIHLLGNPMSTVDREMWGPKIRRIDEPHHKTLYESVSPNTNYTVTVSAITRHKKNGEPATGSCLMPVSTPDAIGRTMWSKVNLDSKYVLKLYLPKISERNGPICCYRLYLVRINNDNKELPDPEKLNIATYQEVHSDNVTRSSAYIAEMISSKYFRPEIFLGDEKRFSENNDIIRDNDEICRKCLEGTPFLRKPEIIHIPPQGSLSNSDSELPILSEKDNLIKGANLTEHALKILESKLRDKRNAVTSDENPILSAVNPNVPLHDSSRDVFDGEIDINSNYTGFLEIIVRDRNNALMAYSKYFDIITPATEAEPIQSLNNMDYYLSIGVKAGAVLLGVILVFIVLWVFHHKKTKNELQGEDTLTLRDSLSRALFGRRNHNHSHFITSGNHKGFDAGPIHRLDLENAYKNRHKDTDYGFLREYEMLPNRFSDRTTKNSDLKENACKNRYPDIKAYDQTRVKLAVINGLQTTDYINANFVIGYKERKKFICAQGPMESTIDDFWRMIWEQHLEIIVMLTNLEEYNKAKCAKYWPEKVFDTKQFGDILVKFAQERKTGDYIERTLNVSKNKANVGEEEDRRQITQYHYLTWKDFMAPEHPHGIIKFIRQINSVYSLQRGPILVHCSAGVGRTGTLVALDSLIQQLEEEDSVSIYNTVCDLRHQRNFLVQSLKQYIFLYRALLDTGTFGNTDICIDTMASAIESLKRKPNEGKCKLEVEFEKLLATADEISKSCSVGENEENNMKNRSQEIIPYDRNRVILTPLPMRENSTYINASFIEGYDNSETFIIAQDPLENTIGDFWRMISEQSVTTLVMISEIGDGPRKCPRYWADDEVQYDHILVKYVHSESCPYYTRREFYVTNCKIDDTLKVTQFQYNGWPTVDGEVPEVCRGIIELVDQAYNHYKNNKNSGCRSPLTVHCSLGTDRSSIFVAMCILVQHLRLEKCVDICATTRKLRSQRTGLINSYAQYEFLHRAIINYSDLHHIAESTLD
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (Q17911)
Organism: Caenorhabditis elegans
Interaction partners:
- Gamma-aminobutyric acid type B receptor subunit 2
- Putative protein tag-53
- BRO1 domain-containing protein
Sequence:
MGQIASVFRGRNTHERGNSHDDEDPEAQITFSNAAGSYFGSHFLMCGCKFEMARPEAYLFGENSDLDQLGSRALSFPYPPGPLGNDEIRPLNLLVNIRKESVKFQRVKKDNGELNANLYQLTFVFDCDSACVIQVHFHAKEMYHDGEIQFAYRNRRPQSSETFHFETGADQVFGGYVFDTSRWDTNDLSYSSGLYYPFVISITTSGVESTQMQTTMCTIETGNDSSKALVLKPLRQKIACDGVTYLLQEIFGIENKSVETMDDDSGLECIICLSDIRDTVILPCRHLCVCSNCADSLRYKHNNCPICRSPFRALIRLRAHRQTRNQIYETVSLVEGLNGSPTPIPTVTDPVNPTVNSSTRRKRHSSSKSSNGKSMHQVLTMEQLGDEEVKECIEMSYIANEHDTDEDDEDEKKRVSEKDVPISQVESEDGSSGSSSQPLQKHHSSVSDISESEEESEPPQREVSKPSEDCESKKSEESEDDERKSQAAHSDDDSVTANEDSARRNSEKRRSFQTSSRNSSSQLLEQNKN
Protein: Insulin [Cleaved into: Insulin B chain; Insulin A chain] (P01308)
Organism: Homo sapiens (Human)
Function: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Subcellular location: Secreted.
Interaction partners:
- Insulin-like growth factor 1
- Insulin-like growth factor 1 receptor
- Insulin-degrading enzyme
- Insulin receptor substrate 1
- Insulin receptor
- Albumin
- Pro-glucagon
- Insulin receptor substrate 2
- High affinity nerve growth factor receptor
- Pro-epidermal growth factor
Sequence:
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Protein: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase) (P32264)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline.
Subcellular location: Cytoplasm.
Interaction partners:
- Gamma-glutamyl phosphate reductase
- Pyrroline-5-carboxylate reductase
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
- Ornithine aminotransferase
- Proline dehydrogenase, mitochondrial
- Uncharacterized protein YHR033W
- Urea amidolyase
- GMP synthase
- Tryptophan synthase
- General control transcription factor GCN4
Sequence:
MKDANESKSYTIVIKLGSSSLVDEKTKEPKLAIMSLIVETVVKLRRMGHKVIIVSSGGIAVGLRTMRMNKRPKHLAEVQAIAAIGQGRLIGRWDLLFSQFDQRIAQILLTRNDILDWTQYKNAQNTINELLNMGVIPIVNENDTLSVREIKFGDNDTLSAITSALIHADYLFLLTDVDCLYTDNPRTNPDAMPILVVPDLSKGLPGVNTAGGSGSDVGTGGMETKLVAADLATNAGVHTLIMKSDTPANIGRIVEYMQTLELDDENKVKQAYNGDLTDLQKREFEKLKALNVPLHTKFIANDNKHHLKNREFWILHGLVSKGAVVIDQGAYAALTRKNKAGLLPAGVIDVQGTFHELECVDIKVGKKLPDGTLDPDFPLQTVGKARCNYTSSELTKIKGLHSDQIEEELGYNDSEYVAHRENLAFPPR