Protein: Neurobeachin-like protein 2 (E7FAW3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis.
Subcellular location: Endoplasmic reticulum {ECO:0000250}.
Interaction partners:
- Serine/threonine-protein kinase greatwall
- RNA-binding protein 8A
Sequence:
MASKERLYELWMLYYTKKDVVYLQQWLEAFVASFEKVIDVHSIEPRRLEEWSADVPLLPKEVLVFLSTQLWHSALHMSGQDQSITAPHPLLLIKFFIIICRNMENIDSEKTPGFVFETIKLLNFCLAQLKKQPDDQSTLQAVVQHGLLLCENLFDPYQTWRRRQAGEEVSMLERSKYKFSPLVLPEELPMLFHEYLQDSELIPEPLVVRLVHLQGAVISGCKRNGLLSITPQAVKDLMSVLRSWCLCPASSPQQPRDPQLLRMALRCLTVMIHLLHSSSVNERQVEIRSALDDYFQLLNWNRPPDSQQGDMHAWEDNLITLLEHMLNAIPEILQCSDRPVLQAIFLNNNCFEHILRLIQNSKLYQSNRFKLECEGQCDLTTRLLTESEVEQVWEKGSDCITVHAIRVLTAIMSNSPSAKEVFKERIGYSQLFDVLKSQGQPTKRLLQELMNMAVEGEHSQAMQLGISNEQPLLLLLQWLPDLGSRSLQLLVSQWLAAVCRGTLSCRTVSVEAGLVGSLLEVLSEPPERLDRQCADSLLGLLQDLGSLSLRPCELKSLLKLLRTEPGAPPHPYCGRVVRVLSAMAARGEGGCSALQYFDLTPPMAGIMVPAIQRWPGSAFAFHAWLCLNTDFPPPQHHYSESHLTNMDNTVRMAKGPRRKQLYSFFTASGTGFEAFFTTEEVLVVAVCTKKEYMAVSLPEHPFNDCAWHSVAIVHVPGRRPFGQNVVTVYVDGVQCKTAPLRFPSLNEPFTSCCIGSAGHRTTTTTMTTSPTLPNPPHSPSEMAFAAHTGPPTLLRSQSFPASFAAAAGGRPGGNRESPVHTIQAGLQDTAWGSPSSLGGLLATAFICHEALQPAQARALFTAGPNNVSLFKADGEPSEVNSKLVLYYTPKAFKSQICLDLSPNHLYDGRLTGHRVVNWDVKDVLSSVGGMGALLPLLEQVCLLDQRETVGQETSDLLGPELTSSRGPAGMLLPLGKSSEGRLEKNSVAAFLLMIKNMLRNHPANQESLLQCHGPAIIGAMLGKVPSSMMDMSVLMACQFLLKQVSNEGNNALLSQLYQYLLFDFRIWSRSHFAVCLGHVQYLTTVINEGKLKTRRKYGVQYILDSIRTHYSVEKDGSPLSDERQTVQISLFSLLKDLLKSPTAEELHSVLAYAAIVQDEQQVISVLDVLHTVLKSSPPPREQVVTVLLDRRVEQLYYLLLKTNYGDEARERLFRVMYKVLKSERVHDRNKQLIKLKDSGYLGLVCSFGDVPITMTTVRCLYEQVLATDPTPSFKDLLAVVYLSHRADLSARLEIVRKLFCLIHSNEEYVKQLAHQSGWQDVLTKLYVKESYESRVRSQSNSLSSPTSSLDPVLSRPVFRRDDSVTEDVRQNVYITLAARHEEEYEEEEGETQDASEGFSDLSQSPPSTGQLKNDSLHFKPFDSGDQSSHSSTLSNTVDFPPSRLQEEDEAVYQPLSPFGSPFELELNHQKGPQTPVGSQPETPSPLEHNKTFLGMRPRKSSSLSNVLDDTSYSTEPPTDTISNTSNPQAPEEELCNLLTNIVFSVLWIGTEGSEDVIWRERGQVFSVLTKLGSSCQLVRPPDDIKRSLLEMMLESSLSDLRDSQGVSLPHVPSLLRLLRLLQDFLFAEGTCNHTLWSEKIFEGVVNLLDRLKAWHTTPGSAGSAELKEMSLIGLRIITGYIQQQQNPQVCEMACLKLHSLLQTVLCLSWEEVCFLLGRLGAPLCPANSASDTSAEGLPSPLVPIVRALLDQHADHTTLQEKLPNLPATNGSPSFAQDLQIYCSTAEWQQFYQNHVEPTMQQYELDTFGKSHDLMSNFWNSCFDDLMSTGQRRDKERSDSKAKFQEVIVDPYLKRVRTENSRYHSVQKMINGQQTVVWRHWRSLRRLLSSDRGAWPLRVQPEVKWKLSSAETYSKMRLKLVPNYSFDSHSDASALRDNMGADSPRSSTEPLPLAVAREAKVSDMDDDKLEDEDIVFLEEAEEAEEESQKEKLVLSEDCELITIVAVVPGRLEVTTHHLYFYDGSSEKEETEEGIGFDFKRPLSQLREVHLRRYNLRRSALELFFIDQSHYFINFRKGVRNKVYSRILGLRPPNLFYFGSRSPQELLKASNLTHRWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSAELDLDDPAVFRDLSKPIGVVNPRHAQNVREKYESFEDPTGTIDKFHYGTHYSNAAGVMHYMIRTEPFTSLHIQLQSGKFDCADRQFHSIAAAWQARMESPADVKELIPEFFYFPEFLENMNGFDLGCLQISQEKVNNVLLPPWASSREDFIRKHRKALESEHVSAHLHEWIDLIFGYKQRGPEAVEALNVFYYCTYEGAVDLDAIANETERKALEGIISNFGQTPCQLLKEPHPPRMSAENAFRRAARLDILPPNLFDQLSKLRSFKEVVSDGLALVQAVVPRNQTRSFIIPGSDILVTVSANGMIGTHSWLPYDKNIANYFTFTRDPSVSNPKTQRFLSGPFSPGVEMGSQVLVVSSDGRLLFSGGHWDCSLRVTMLGKAKLVGRICRHIDVVTCLALDLCGIYLISGSRDTTCMVWQVLQQGGFSSGLSPRPIQVLCGHDQEVTCVAISTELDMAISGSKDGTVIVHSVRRGQYLWTLRPPCENCVSAPVAQLEVGMEGHIVMQTVLEGRSAGKERYALHVYSVNGTLLASETLDEKISALYLVPDYLIVGTQQGNLHIRDLYSLNLAVAPLALKVPVRCVSVTKESSHILVGLEDGKLIVVGAGKPEEVRSGQFSRRLWGSTRRISQVSSGETEYNPVEAPAK