wanglab/gogpt-training-data huggingface dataset:
Protein: WIZ zinc finger (A0A669KAV7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEGSLAGSLAAPDRPQGPERLPGPAPRENIEGGAEAAEGEGGIFRSTRYLPVTKEGPRDILDGRGGISDGQPHPGLSEALPRVTSATHRISSCCWDGGSLDFRPGSPPPHLLGHFPGTPDGRGPWEHPLVQEAGEGILSERRFEDSVIVRTMKPHAELEGSRRFLHHRGEPRLLEKHAQGRPRFDWLQDEDEQGSPQDAGLHLDLPAQPPPLAPFRRVFVPVEDTPKTLDMAVVGGREDLEDLEGLAQPSEWGLPTSASEVATQTWTVNSEASVERLQPLLPPIRTGPYLCELLEEVAEGVASPDEDEDEEPAVFPCIECSIYFKQKEHLLEHMSQHRRAPGQEPPADLAPLACGECGWAFADPTALEQHRQLHQASREKIIEEIQKLKQVPGDEGREARLQCPKCVFGTNSSRAYVQHAKLHMREPPGQTTKEPFGGSSGAGSPSPEASALLYQPYGAAVGLSACVFCGFPAPSESLLREHVRLVHAHPHWEEDGEAYEEDPASQPGTSQDAHACFPDTAVDYFGKAEPSLAPMWRENPAGYDPSLAFGPGCQQLSIRDFPLSKPLLHGTGQRPLGRLAFPSTLASTPYSLQLGRNKSTVHPQGLGERRRPWSEEEEEEEEEEDVVLTSEMDFSPENGVFSPLATPSLIPQAALELKQAFREALQAVEATQGQQQQLRGMVPIVLVAKLGPQVMAAARVPPRLQPEELGLAGAHPLDFLLLDAPLGGPLGLDTLLDGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAEQPPSPLGREPGGPPGSFLTSRRPRLPLTVPFPPTWAEDPGPAYGDGLGSEENAMVAMDLGSPSLPKKSLPVPGALEQVASRLSSKVAAEVPHGSKQELQDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAHLGLPPGLAKKSSSLKEVVAGAPRPGLLSLAKPLDAPAVNKAIKSPPGFSAKGLGHPPSSPLLKKTPLALAGSPTPKNPEDKSPQLSLSPRPASPKAQWPQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGVQIRLPPRRGALAHPGRPPPTSAALSLLPPPPPAKKAKLKAAGMASPWGKQDLSAAAAAGIFWASDVEPSPLNLSSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPPGPSPKALAKMMGGAGPGSSLEARSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFPGLAAPSLPKKLKPEQIRVEIKREMLPGALHGELHPSEGPWGAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALAEDGPPTVAPGPVQSPLPLSPLAGRPGKPGAGPAQVPRELSLTPITGAKPSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKVGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPSLGLAPGGLAVVGRSAGGEPGPEAGRAADGGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGGEDTNDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEESQAPQAQTAAAEAP
Protein: Transmembrane protein 114 (Claudin-26) (Q9D563)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000269|PubMed:21689651}; Multi-pass membrane protein {ECO:0000269|PubMed:21689651}. Note=N-glycosylation at Asn-54 and Asn-88 is required for plasma membrane localization.
Interaction partners:
- Charged multivesicular body protein 4b
- Lens fiber membrane intrinsic protein
- Alpha-crystallin A chain
Sequence:
MRVRLGALAGAAALSGALSFVLLAAAIGTDFWYIIDTERLERSSQRMRDQGPANRSQQEPLSSHSGLWRTCRVQSSCTPLMNPFWQENVTVSDSSRQLLTMHGTFVILLPLSLIVMVFGGMTGFLSFLLRAHLLLLLTGILFLFGAMVTLTGISIYIAYSAVAFREAVCLLEERALLDQVDIRFGWSLALGWISFVSELLTGVVFLAAARALSLSQRQDQAI
Protein: Ferredoxin--NADP reductase, leaf isozyme 2, chloroplastic (EC 1.18.1.2) (Leaf FNR 2) (AtLFNR2) (FNR-2) (Q8W493)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|Ref.5}. Plastid, chloroplast thylakoid membrane {ECO:0000269|Ref.5}; Peripheral membrane protein {ECO:0000269|Ref.5}; Stromal side {ECO:0000269|Ref.5}. Note=More abundant in the soluble fraction. The presence of LFNR1 is required for association with the thylakoid membrane.
Interaction partners:
- Protein TIC 62, chloroplastic
- Rhodanese-like domain-containing protein 4, chloroplastic
- Ferredoxin-2, chloroplastic
- Ferredoxin-1, chloroplastic
- Photosystem II 22 kDa protein, chloroplastic
- Ferredoxin--nitrite reductase, chloroplastic
- Assimilatory sulfite reductase
- ATP synthase gamma chain 1, chloroplastic
- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic
- Photosystem I reaction center subunit V, chloroplastic
Sequence:
MATTMNAAVSLTSSNSSSFPATSCAIAPERIRFTKGAFYYKSNNVVTGKRVFSIKAQITTETDTPTPAKKVEKVSKKNEEGVIVNRYRPKEPYTGKCLLNTKITADDAPGETWHMVFSHQGEIPYREGQSVGVIADGIDKNGKPHKVRLYSIASSALGDLGNSETVSLCVKRLVYTNDQGETVKGVCSNFLCDLAPGSDVKLTGPVGKEMLMPKDPNATVIMLATGTGIAPFRSFLWKMFFEKHDDYKFNGLAWLFLGVPTTSSLLYQEEFDKMKAKAPENFRVDYAISREQANDKGEKMYIQTRMAQYAAELWELLKKDNTFVYMCGLKGMEKGIDDIMVSLAANDGIDWFDYKKQLKKAEQWNVEVY
Protein: Protocadherin gamma subfamily C, 5 (A0A0A6YXZ9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MRPMASPQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNA
Protein: Beta carbonic anhydrase 4 (AtbCA4) (AtbetaCA4) (EC 4.2.1.1) (Beta carbonate dehydratase 4) (Q94CE4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Reversible hydration of carbon dioxide. Together with BCA1, involved in the CO(2) signaling pathway which controls gas-exchange between plants and the atmosphere by modulating stomatal development and movements. Promotes water use efficiency.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17407539, ECO:0000269|PubMed:20010812}; Peripheral membrane protein {ECO:0000269|PubMed:17407539, ECO:0000269|PubMed:20010812}.
Interaction partners:
- Cyanate hydratase
- Alpha carbonic anhydrase 4
- Protein DETOXIFICATION 56
- Alpha carbonic anhydrase 2
- Serine/threonine/tyrosine-protein kinase HT1
- Alpha carbonic anhydrase 1, chloroplastic
- BTB/POZ domain-containing protein At3g50780
- Alpha carbonic anhydrase 3
- CO
- Tubulin-folding cofactor D
Sequence:
MAPAFGKCFMFCCAKTSPEKDEMATESYEAAIKGLNDLLSTKADLGNVAAAKIKALTAELKELDSSNSDAIERIKTGFTQFKTEKYLKNSTLFNHLAKTQTPKFLVFACSDSRVCPSHILNFQPGEAFVVRNIANMVPPFDQKRHSGVGAAVEYAVVHLKVENILVIGHSCCGGIKGLMSIEDDAAPTQSDFIENWVKIGASARNKIKEEHKDLSYDDQCNKCEKEAVNVSLGNLLSYPFVRAEVVKNTLAIRGGHYNFVKGTFDLWELDFKTTPAFAFS
Protein: Protein PHYLLO, chloroplastic [Includes: Inactive isochorismate synthase (MENF); 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (EC 2.2.1.9) (MEND); o-succinylbenzoate synthase (EC 4.2.1.113) (MENC); 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) (MENH)] (Q15KI9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Multifunctional enzyme required for phylloquinone (vitamin K1) biosynthesis.
Subcellular location: Plastid, chloroplast membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- 2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomal
- indole-3-glycerol-phosphate synthase
- Indole-3-glycerol phosphate synthase, chloroplastic
- Chorismate synthase, chloroplastic
- anthranilate synthase
- Anthranilate synthase beta subunit 2, chloroplastic
- Anthranilate synthase beta subunit 1, chloroplastic
- anthranilate synthase
- Anthranilate phosphoribosyltransferase
- Anthranilate phosphoribosyltransferase, chloroplastic
Sequence:
MRSSFLVSNPPFLPSLIPRYSSRKSIRRSRERFSFPESLRVSLLHGIRRNIEVAQGVQFDGPIMDRDVNLDDDLVVQVCVTRTLPPALTLELGLESLKEAIDELKTNPPKSSSGVLRFQVAVPPRAKALFWFCSQPTTSDVFPVFFLSKDTVEPSYKSLYVKEPHGVFGIGNAFAFVHSSSVDSNGHSMIKTFLSDESAMVTAYGFPDIEFNKYSTVNSKDGSSYFFVPQIELDEHEEVSILAVTLAWNESLSYTVEQTISSYEKSIFQVSSHFCPNVEDHWFKHLKSSLAKLSVEEIHPLEMEHMGFFTFSGRDQADVKELKSIQSSCQFHCKLSPDVVFSNNMLNRETEVSNFLRDEANINAVWASAIIEECTRLGLTYFCVAPGSRSSHLAIAAANHPLTTCLACFDERSLAFHAIGYAKGSLKPAVIITSSGTAVSNLLPAVVEASEDFLPLLLLTADRPPELQGVGANQAINQINHFGSFVRFFFNLPPPTDLIPVRMVLTTVDSALHWATGSACGPVHLNCPFRDPLDGSPTNWSSNCLNGLDMWMSNAEPFTKYFQVQSHKSDGVTTGQITEILQVIKEAKKGLLLIGAIHTEDEIWASLLLAKELMWPVVADVLSGVRLRKLFKPFVEKLTHVFVDHLDHALFSDSVRNLIEFDVVIQVGSRITSKRVSQMLEKCFPFAYILVDKHPCRHDPSHLVTHRVQSNIVQFANCVLKSRFPWRRSKLHGHLQALDGAIAREMSFQISAESSLTEPYVAHMLSKALTSKSALFIGNSMPIRDVDMYGCSSENSSHVVDMMLSAELPCQWIQVTGNRGASGIDGLLSSATGFAVGCKKRVVCVVGDISFLHDTNGLAILKQRIARKPMTILVINNRGGGIFRLLPIAKKTEPSVLNQYFYTAHDISIENLCLAHGVRYVHVGTKSELEDALFVPSVEEMDCIVEVESSINANAIVHSTLERFARQAAENSLGIVSASSFLHPMIKNVLLCQVSGIQYSQYRVKLCDRPTICSDEFSQFHREGFILSLTLEDGSIGYGEVAPLNSNVENLMDVEGQLQLVLHLMNEAKFSYMLPLLNGSISSWIWSELGITASSIFPSVRCGLEMALLNAMAVRHDSSLLGILHYQKEENGSAQPHSVQICALLDSEGTPLEVAYVARKLVQEGFSAIKLKVGRRVSSVQDALVMQEVRRAVGVQIELRADANCRWTFEEAREFGLLVNSCNLKYIEEPVQNKDDLIRFHEETGLPVALDETLDDFEECPLRMLTKYTHPGIVAVVIKPSVVGGFENAALIARWAQQHGKMAVISAAYESGLGLSAYILFASYLEMENVKASTEQKQGTPPSVAHGLGTYRWLSEDVMMNTLGIFRSPYSGFVEGFIADASRNLKDVKINNDVIVRTSKGIPVRRYELRVDVDGFSHFIRVHDVGENAEGSVALFLHGFLGTGEEWIPIMTGISGSARCISVDIPGHGRSRVQSHASETQTSPTFSMEMIAEALYKLIEQITPGKVTIVGYSMGARIALYMALRFSNKIEGAVVVSGSPGLKDPVARKIRSATDDSKARMMVDNGLYIFIENWYNGGLWKSLRNHPHFSKIAASRLLHGDVPSVAKLLSDLSSGRQPSLWEELEDCDTNISLVFGEKDVKYKQIATRMYREMSKSKKSVNNIIEIVEIPEAGHAVHLESPLRVILALRKFLTRVHNSSTETELSQKLLLALKEM
Protein: Cystinosin, lysosomal cystine transporter (A0A669KB82)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MNWRRKSVIGLSFDFVALNLTGFVAYSVFNIGLLWVPYIKEQFLLKYPNGVNPVNSNDVFFSLHAVVLTLIIIVQCCLYERGGQRVSWPAIGFLVLAWLFAFVTMIVAAVGVTTWLQFLFCFSYIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGVFSIVFDVVFFIQHFCLYRKRPGYDQLN
Protein: Myosin-8 (Myosin XI B) (AtXIB) (F4I460)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17288617}. Note=Colocalizes with cytoplasmic vesicles and/or organelles.
Interaction partners:
- T-complex protein 1 subunit alpha
Sequence:
MVATFNPAVGSHVWVEDPDEAWLDGEVVEINGDQIKVLCASGKQVVVKDSNIYPKDVEAPASGVEDMTRLAYLHEPGVLQNLQSRYDINEIYTYTGSILIAVNPFRRLPHLYSSHMMTQYKGASLGELSPHPFAVADAAYRQMVNEGVSQSILVSGESGAGKTESTKLLMRYLAFMGGRGAATEGRTVEQKVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDQSGRISGAAIRTYLLERSRVCQVSDPERNYHCFYMLCAAPEEDAKKFKLGDPKIYHYLNQSKCIQLDAMNDAEEYHATKKAMDVVGISSEEQDAIFRVVASILHLGNIEFAKGTEIDSSIPRDEKSWFHLKTAAELLMCNEKSLEDSLCKRIMATRDETITKTLDPEAALLSRDALAKVMYSRLFDWLVEKINTSIGQDPDSKYLIGVLDIYGFESFKTNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEINWSYIEFVDNQDILDLIEKKPGGIIALLDEACMFPRSTHETFAQKLYQTYKNHKRFTKPKLARSDFTICHYAGDVTYQTELFLDKNKDYVIAEHQALLNASTCSFVANLFPPVSDDSKQSKFSSIGTRFKQQLVSLLEILNTTEPHYIRCIKPNNLLKPGIFENQNVLQQLRCGGVMEAIRISCAGYPTRKHFDEFLNRFGIIAPQVLDKNSNEPAACKKLLDKAGLEGYQIGKSKVFLRAGQMADLDTRRTEILGRSASIIQRKVRSYLAQKTFIQLRISATQIQAVCRGYLARSIYEGMRREAAALKIQRDLRKFLARKAYTELFSATILIQAGMRGMVSRKELCLRRQTKAATIIQTRCRVYLARLHYRKLKKAAITTQCAWRGKVARKELKNLKMAARETGALQEAKNKLEKQVEELTWRLQLEKRMRTDLEEAKKQENAKYESSLEEIQNKFKETEALLIKEREAAKTVSEVLPIIKEVPVVDQELMEKLTNENEKLKGMVSSLEIKIDETAKELHETARISQDRLKQALAAESKVAKLKTAMQRLEEKISDMETEKQIMLQQTILNTPVKSVAGHPPTATIKNLENGHRTNLENQFNEVEVNGNAGKSAAERQLENVDTLIDCVKENIGFSNGKPIAAFTIYKCLLHWKCFESEKTSAFDRLIEMIGSAIENEDDNGHLAYWLTNTSALLFLLQKSLKPAGAGATASKKPPITTSLFGRMALSFRSSPNLAAAAEAAALAVIRPVEAKYPALLFKQQLAAYVEKIFGMIRDNLKKELSALISMCIQAPRISKGGIQRSARSLGKDSPAIHWQSIIDGLNSLLAILKDNYVPLVLIQKIHTQTFSFVNVQLFNSLLLRKECCTFSNGEFVKSGLAELELWCGQVNEYAGPSWDELKHIRQAVGFLVIHQKYRVSYDDIVHDLCPILSVQQLYRICTLYWDDCYNTRSVSQEVISSMRALMTEESNDADSNSFLLDDNSSIPFSIDEISNSMHEKDFASVKPAKELLENPEFVFLH
Protein: Elongator complex protein 2 (F4I1S8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSENTKVEAKRVFIGAGCNRVVNNVSWGASGLVSFGAQNAVAVFCPKTAQILTTLPGHKASVNCTHWLPTSKFAFKAKKLDRQYLLSGDSDGIIILWELSTLNNDQQWRHVLQLPLSHKKGVTCITAYMVSETDAMFASASSDGVVNVWDVSFPSQPSEECKVVCLDSICVDTKAIVTLSLAELPQNPGRFALALGGLDNKIKLYSGERTGKFTSVCELKGHTDWIRSLDFSLPLHTTEEIPNSIMLVSSSQDKVIRIWKLVLVGDVGSWRREITLASYIEGPVFVSGTFTYQISVESVLIGHEDWVYSVEWQPPVIDFIDGRLVNHQPLSILSASMDKTMMIWRPEKKTGVWVNVVCVGELSHCALGFYGGHWSPNSLSILAHGYGGAFHLWRNVSSSKESENWQMQKVPSGHFAAVTDVTWARTGEYLLSVSQDQTTRVFSAWKNDEGNEAEDEHWHELARPQVHGHDINCVAMVQGKGNHRFVSGAEEKVVRVFEAPLSFLKTLNHTCAGGEGSFPEDLQADVQVLGANMSALGLSQKPIYLHSSSEPLERNGGGEGLDTFETVPEAAPAELKEPPIEDQLAFHTLWPESHKLYGHGNELFSLCSDHKGNLVASSCKAQSASMAEIWLWEVGTWKAVGRLQSHSLTVTHLEFSYDDTLLLSVSRDRHFSVFSIQRTDNGEVSHKLMAKVEAHKRIIWACSWNPFGHQFATSSRDKTVKIWSVENDARIKQILVLPPFGSSVTAVAWTGLDRNEKSGCVAVGMESGLIELSNVKIIETEEGTTATAALALRLEPFMCHVSAVNRLAWRPTEKCESNQSLRWLTSCGDDNCVRVFNFKF
Protein: Phospholipid-transporting ATPase 10 (AtALA10) (EC 7.6.2.1) (Aminophospholipid flippase 10) (Q9LI83)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in transport of phospholipids.
Subcellular location: Cell membrane {ECO:0000305|PubMed:15308754}; Multi-pass membrane protein {ECO:0000305|PubMed:15308754}.
Interaction partners:
- ALA-interacting subunit 5
- ALA-interacting subunit 1
- Delta
- Acyl-lipid omega-3 desaturase
- S-protein homolog 1
- Expressed protein
- Monogalactosyldiacylglycerol synthase 1, chloroplastic
- AT5g23340/MKD15_20
- Probable LRR receptor-like serine/threonine-protein kinase At4g37250
- At4g27652
Sequence:
MAGPSRRRRRLHLSKIYSYTCGKSSFQEDHSNIGGPGFSRVVYCNEPGSPAAERRNYAGNYVRSTKYTVASFFPKSLFEQFRRVANFYFLVTGILSLTDLSPYGAVSALLPLALVISATMVKEGIEDWRRKQQDIEVNNRKVKVHDGNGIFRQEEWRNLRVGDIVRVEKDEFFPADLLLLSSSYEDSVCYVETMNLDGETNLKVKQGLEATSSLLNQDSDFKDFRGVVRCEDPNVNLYVFVGTLALEEERFPLSIQQILLRDSKLRNTEYVYGAVVFTGHDTKVIQNSTDPPSKRSRIERTMDKIIYLMFGLVFLMSFVGSIIFGVETREDKVKNGRTERWYLKPDDADIFFDPERAPMAAIYHFFTATMLYSYFIPISLYVSIEIVKVLQSIFINRDIHMYYEETDKPAQARTSNLNEELGMVDTILSDKTGTLTCNSMEFIKCSIAGKAYGRGITEVERAMAVRSGGSPLVNEDLDVVVDQSGPKVKGFNFEDERVMNGNWVRQPEAAVLQKFFRLLAVCHTAIPETDEESGNVSYEAESPDEAAFVVAAREFGFEFFNRTQNGISFRELDLVSGEKVERVYRLLNVLEFNSTRKRMSVIVRDDDGKLLLLSKGADNVMFERLAKNGRQFEAKTQEHVNQYADAGLRTLVLAYREVDENEYIEFNKSFNEAKASVSEDREALIDEITDKMERDLILLGATAVEDKLQNGVPECIDKLAQAGIKIWVLTGDKMETAINIGFASSLLRQEMKQIIINLETPQIKSLEKSGGKDEIELASRESVVMQLQEGKALLAASGASSEAFALIIDGKSLTYALEDEIKKMFLDLATSCASVICCRSSPKQKALVTRLVKSGTGKTTLAIGDGANDVGMLQEADIGVGISGVEGMQAVMSSDIAIAQFRYLERLLLVHGHWCYSRIASMICYFFYKNITFGVTVFLYEAYTSFSGQPAYNDWFLSLFNVFFSSLPVIALGVFDQDVSARFCYKFPLLYQEGVQNILFSWKRIIGWMFNGFISALAIFFLCKESLKHQLFDPDGKTAGREILGGTMYTCVVWVVNLQMALSISYFTWVQHIVIWGSIAFWYIFLMIYGAMTPSFSTDAYMVFLEALAPAPSYWLTTLFVMIFALIPYFVYKSVQMRFFPKYHQMIQWIRYEGHSNDPEFVEMVRQRSIRPTTVGYTARRAASVRRSARFHDQIYKDLVGV
Protein: Protein NIF3 homolog (O94404)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Probable aminomethyltransferase, mitochondrial
- Probable cytosolic Fe-S cluster assembly factor SPAC806.02c
- Iron-sulfur cluster assembly factor IBA57
Sequence:
MSKANISSKLKKVVESIYNPKLADSWDNTGLLLEAPFPRTNASSVLLTIDLTEKVAEEAISNKLVSSIVAYHPIIFRGLKAITMEDPQQRSLLKLAAEGIHVYSPHTAVDAAVDGVNDWLAQGIAGGRNNIKSVVPTQQNSVMAEAEGYGRICELKIPTTLRELVQRAKELTGLQYVQVCAPNGLDSHISKVSLCAGSGGSVVMNTDADLYFTGELSHHQVLAAMAKGISVILCGHSNTERGYLKDVMCQKLASSFHKEGVDANVIVSSMDADPLTTM
Protein: PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4) (Q9UKN5)
Organism: Homo sapiens (Human)
Function: May function as a transcription factor involved in cell differentiation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 16
- Protein arginine N-methyltransferase 5
- Beta-nerve growth factor
Sequence:
MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK
Protein: Lymphocyte transmembrane adapter 1 (Linker for activation of X cells) (Membrane-associated adapter protein LAX) (Q8IWV1)
Organism: Homo sapiens (Human)
Function: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12359715}; Single-pass type III membrane protein {ECO:0000269|PubMed:12359715}.
Interaction partners:
- Ras-related protein Rab-8A
- T-cell receptor-associated transmembrane adapter 1
- Growth factor receptor-bound protein 2
- Growth factor receptor-bound protein 7
Sequence:
MDGVTPTLSTIRGRTLESSTLHVTPRSLDRNKDQITNIFSGFAGLLAILLVVAVFCILWNWNKRKKRQVPYLRVTVMPLLTLPQTRQRAKNIYDILPWRQEDLGRHESRSMRIFSTESLLSRNSESPEHVPSQAGNAFQEHTAHIHATEYAVGIYDNAMVPQMCGNLTPSAHCINVRASRDCASISSEDSHDYVNVPTAEEIAETLASTKSPSRNLFVLPSTQKLEFTEERDEGCGDAGDCTSLYSPGAEDSDSLSNGEGSSQISNDYVNMTGLDLSAIQERQLWVAFQCCRDYENVPAADPSGSQQQAEKDVPSSNIGHVEDKTDDPGTHVQCVKRTFLASGDYADFQPFTQSEDSQMKHREEMSNEDSSDYENVLTAKLGGRDSEQGPGTQLLPDE
Protein: NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit 4L) (NADH-plastoquinone oxidoreductase subunit 4L) (P0C334)
Organism: Oryza sativa subsp. japonica (Rice)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01456}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01456}.
Interaction partners:
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NADH-ubiquinone oxidoreductase chain 1
- NAD
- NADH-ubiquinone oxidoreductase chain 5
Sequence:
MMFEHVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNFLNN
Protein: Spore germination protein GerPE (A0A2P0HB91)
Organism: Bacillus anthracis
Interaction partners:
Sequence:
MLHHVSVVQNVSIISLGITAVFQVGDANQMELKSRALAVHREIPCYIKDEGRLDAFEIFTDEYITIPKRTTDVKLNIVNECPFIEVNSVELRTLLNSGCFQIGNVDYVFNNSRIMQIRQYITDEPSVQ
Protein: Uncharacterized protein YHR033W (P38690)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11914276}.
Interaction partners:
- Gamma-glutamyl phosphate reductase
- Ornithine aminotransferase
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
- Glutamate 5-kinase
- Urea amidolyase
- Pyrroline-5-carboxylate reductase
- Tryptophan synthase
- Protein ARG5,6
- Glutamate synthase
- GMP synthase
Sequence:
MTKAYTIVIKLGSSSLVDESTKEPKLSIMTLIVETVTNLKRMGHKVIIVSSGGIAVGLDALNIPHKPKQLSEVQAIAAVGQGRLIARWNMLFSQYGEQTAQILLTRNDILRWNQYNNARNTINELLAMGVIPIVNENDTLSISEIEFGDNDTLSAITAALVGADFLFLLTDVDCLYTDNPRTNPDARPIVLVPELSEGLPGVNTSSGSGSEVGTGGMRTKLIAADLASNAGIETIVMKSDRPEYVPKIVDYIQHHFRPPRHIGNGTQQQFLDLQDTELEQLRRYDVPMHTKFLANDNKHKLKNREFWILHGLITKGAIIIDENSYDKLLSKDMASLTPNAVIEVRDNFHELECVDLKIGQRLPNGELDISKPIQSVGCVRSNYTSLELAKIKGLPSEKIHDVLGYSVSEYVAHRENIAFPPQF
Protein: FAD-binding PCMH-type domain-containing protein (Q57ZU1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Isopentenyl-diphosphate delta-isomerase, putative
- Dihydroxyacetone phosphate acyltransferase, putative
- 4-hydroxybenzoate polyprenyltransferase, mitochondrial
Sequence:
MGQETMSDGTWTNFANIGKCFPRKHHYPNTVEEVSSIIKVINSAGERCRVVGGGKSPNSCTFTNGHLIHMDRLNRITSIDEKSMTIVCEGGALISDVFERLSAHDLMLRCVPSFVQTTVGGVIATATHSSGIRSRSISDCVVRLQLVDGRGILHTFDASTPKELSLSACHLGMLGVVVSVTLQAEKKRLWRIESRPIPFRKLTEGDTLKKRIAESEFYRFFWMPNTDQCYESTAEFVGEEGADQTKRVDESIKLAMGKKHEATLPMTAGNTITKLTSSKLRNFSSEKCNSTGEDYQMWLRNQRTLRTRICKILKGSWLRHGVVEAALAAAVIQPGIQPYINRTYRRLFYNAPEVQYGTSLECFTFDCLFKQWACEWAIDISNVMPAFHYLRGLISSENLSVHFPVEFRFTGADTAALSPAHGRQTCWIGIVMYRPYLRHARDTLRYYDAFSKAMTVMGGRPHWAKYYTWGPEQMLKAYGKNWEDFLLFRKKMDPEGVFLNGWFNSLSGNSPVLNSTISHL
Protein: Pre-mRNA-splicing factor URN1 (U2-U5-U6 snRNP, RES complex and NTC-interacting pre-mRNA-splicing factor 1) (Q06525)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the spliceosome involved in mRNA processing.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pre-mRNA-splicing factor CLF1
- U1 small nuclear ribonucleoprotein component SNU71
- Pre-mRNA-splicing factor RSE1
- Pre-mRNA-splicing factor CEF1
- Protein LUC7
- Protein HSH49
- Cold sensitive U2 snRNA suppressor 1
- Pre-mRNA-processing protein PRP40
- U2 small nuclear ribonucleoprotein A'
- Pre-mRNA-splicing factor SYF1
Sequence:
MRGEWQEFKTPAGKKYYYNKNTKQSRWEKPNLKKGSNLESNAKESQTERKPTFSLELVNGWHLIIYNDGTKLYFNDDSKEFKNDISQEDDSRCRSLIESLDKEKLVLLIGVARGYTMREEDIDKILESCNEEIHLFKRNQDEVERKDEISEEAGDVKSPLQESHTGLVSGYGSSSGEEDEEEDEEEDEENEEQIVNQDISIIDDLNRIDTDDIDERNIFFELFDRYKLDKFSTWSLQSKKIENDPDFYKIRDDTVRESLFEEWCGERSGNATAEESDSEDNSEDDSEVLEPTKYHYLAQIVANAGTIAPDTIPQDIRKQQKALYKAYKIKEYIPSKRDQDKFVSQLLFYYKTFDLEQRKEIFCDCLRDHERDFTGAVESLRQDKELIDRWQTLLKAPADSSSIEDILLSIEHRCCVSPIVVTEPRYYVVGILEKTVVWVRWLAAEVGPSSRFTPVGAGNEPINPE
Protein: Oxysterol-binding protein homolog 3 (Oxysterol-binding protein-related protein 3) (ORP 3) (OSBP-related protein 3) (P38713)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Lipid transport protein (LTP) involved in non-vesicular transfer of lipids between membranes. Functions in phosphoinositide-coupled directional transport of various lipids by carrying the lipid molecule in a hydrophobic pocket and transferring it between membranes through the cytosol. Involved in maintenance of intracellular sterol distribution and homeostasis. May serve as a sensor of PI4P levels at PM-ER membrane contact site, regulating PI4P phosphatase SAC1 activity. May be involved in ergosterol transport from the plasma membrane (PM) to the ER, however it does not bind sterols directly. Plays a role in the positive regulation of vesicular transport of ceramide from the ER to the Golgi, negatively regulating COPII-mediated ER export of cargos.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11408574, ECO:0000269|PubMed:12727870, ECO:0000269|PubMed:20008566}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:20008566}. Note=Enriched at the cell periphery in a SCS2-dependent manner (PubMed:12727870). Enriched on regions of the ER in close proximity with the plasma membrane (PM), which may represent PM-ER membrane contact sites (MCS) (PubMed:20008566). Localizes to PM-ER membrane contact sites dependent upon PM PI4P levels (PubMed:21295699). {ECO:0000269|PubMed:12727870, ECO:0000269|PubMed:20008566, ECO:0000269|PubMed:21295699}.
Interaction partners:
- Vesicle-associated membrane protein-associated protein SCS2
- Vesicle-associated membrane protein-associated protein SCS22
- Oxysterol-binding protein homolog 4
- Phosphatidylinositol-3-phosphatase SAC1
- Phosphatidylinositol 4-kinase STT4
- Oxysterol-binding protein homolog 2
- Oxysterol-binding protein homolog 1
Sequence:
METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKLKSSVDDHASAVHIAPDTKTLLDYTTKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKRKERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQGDLEVKDTDYYYAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDKIIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPDILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERRNKGQDVEPKYFEKVSKNEWKYITGPKSYWERRKKHDWSDISQLW
Protein: Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (P84140)
Organism: Thermococcus litoralis
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MKYKEPFGVKLDFETGIIENAKKSVRRLSDMKGYFIDEEAWKKMVEEGDPVVYEVYAIEQEEKEGDLNFATTVLYPGKVGNEFFMTKGHYHSKIDRAEVYFALKGKGGMLLQTPEGEARFIEMEPGTIVYVPPYWAHRTINTGDKPFIFLALYPADAGHDYGTIAEKGFSKIVVEENGKVVVKDNPKWRM