wanglab/gogpt-training-data huggingface dataset:
Protein: Tyrosine decarboxylase (OsTyDC) (EC 4.1.1.25) (Trypthophan decarboxylase) (Q94EE9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the decarboxylation of L-tyrosine to tyramine, which can be converted to the hydroxycinnamic acid amides feruloyltyramine and 4-coumaroyltyramine. Possesses low tryptophan decarboxylase activity.
Interaction partners:
- Serotonin N-acetyltransferase 1, chloroplastic
- Serotonin N-acetyltransferase 2, chloroplastic
- Delta-1-pyrroline-5-carboxylate synthase 1
- Delta-1-pyrroline-5-carboxylate synthase 2
- histidinol-phosphate transaminase
- Os07g0182100 protein
- Aspartate aminotransferase
- Tryptophan synthase
- Aspartate aminotransferase, cytoplasmic
- Tryptophan decarboxylase 2
Sequence:
MAPPSHCHTINGGAPRNGAIPEVETTTSTPAASDTALLLDADEFRRLGHQVVDFIADYYAGLGDYPVHPSVTPGFLRRQLPADAPSRPEPEAFAAALRDVRDLILPGVTHWQSPRHFAHFPASSSTVGALGEALAAGINVVPFTWAASPAATELEMVVVDWLGRALHLPESLLFAGGGGGTILGTSCEAVLCALVAARDRKLAEIGARRIGDLVVYCSDQTHFAFRKAARIAGIPREHCREIPTCRDDVFALSPTALHAAMQADVDAGLVPLFLCATVGTTQTTAVDPVRELCAVAARHGGVWVHVDAAYAGSALVCPEFRDVIAGAEAVDSLSMNAHKWLLANNDCCAVWVAAPSALVAALGTEQEYILRDAAAEGHDVVDYKDWGTTLTRRFRALKVWLVLRCYGVEGLRSHVRSHVAMAAAFEAMVRGDARFEVVAPRRFALVCFRLRSPPERLGVGVGVGGEKAANELNRRLLEEVNAASSGPYMSSAMVGGVYMLRCAIGSTLTEERHVREAWKVVQERATSILRKRG
Protein: Probable peroxidase (Q9HY81)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Alkyl hydroperoxide reductase subunit F
- Catalase HPII
- Thioredoxin reductase
Sequence:
MSVLVGKKAPDFNVAAVLGNGEIVESFTLSEAIKGKYGLVFFYPLDFTFVCPSELIALDHRIPEFQARNVEVIGVSIDSHFTHNAWRNTPVDKGGIGAVKYTLAADTKHEIAKAYDVESDGGVAFRGAFLIDKEGVVRSQIVNDLPLGRNMDELLRLVDALQFHEEHGEVCPANWKKGDKGMTASPEGVAKYLAENASKL
Protein: Protein pkiA (Protein DD-1) (Q23921)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSESVGNIRIDPRDTIFAKIISGAIPSKKFYDDEYCIAIEDINPQAPVHLLVIPKLAVGGLSDVANVDLEKYKESMGHIMSKIHHIASLKGADSYRLVINEGVLGQQSVRWLHIHILGGRQMNWPPG
Protein: glucuronosyltransferase (EC 2.4.1.17) (F1R1P2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
Sequence:
MPLCSTSFGGMKRTLFVPALGLFAFLCLFSSESVQAGKVLVMPVDGSHWLSMKILVEEMSSRGHEMVVLVPETSILIGKSGNFTTKSFRVPYSFDELNAHVDHIRKTAIEKAPRFIDIVGALGNLIQFTNMQVKACEGLLYDEPLMKSLRDMKFDALLTDPFLPCGSVIADYFSIPAVYFLRGIPCRLDEAAAQCPSPPSFIPRFFTGYTDKMTFPQRMINTFMTVFEKYLCHQLFASFDELATRYLKKDTSYAELLGHGAVWLLRYDFSFEYPKPQMPNMVQIGGINCAKRAPLTKELEEFVNGSGEHGFVVFTLGSMVSQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA
Protein: (+)-menthofuran synthase (EC 1.14.14.143) ((+)-pulegone 9-hydroxylase) (Q947B7)
Organism: Mentha piperita (Peppermint) (Mentha aquatica x Mentha spicata)
Function: Monoterpene synthase that catalyzes the formation of (+)-menthofuran from (+)-pulegone.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAALLVFFSVSLILLAVLFHKRKSSLSSRKRPPPSPLRLPVIGHFHLIGALSHRSFTSLSKRYGEVMLLHFGSAPVLVASSAAAAREIMKNQDVIFASRPRLSIFDRLMYSGKGVAFAPYGEHWRNARSMCMLQLLSAKRVQSFGGIREEETSAMIEKIRRSKPTTVVNLSEMFMALTNGVIHRAVLGRKGDGGDDFNRILIKVIKLLGSFNVGDYVPWLSWINRINGVDAEVEKVGTKLDGSMEGILRKYRRKKVGDDETNFVDTLLQFQRESKDTDPVEDDVIKALIFDMVSAGTDTTFAALEWTMAELIKNPRTLKTLQNEVREVSRNKGGITEDDVDKMPYLKAVSKEILRLHPPFAILLPRELTQDANMLGYDIPRGTVVLVNNWAISRDPSLWENPEEFRPERFLETSIDYKGLHFEMLPFGSGRRGCPGSTFAMALYELALSKLVNEFDFRLGNGDRAEDLDMTEAPGFVVHKKSPLLVLATPRQS
Protein: Peroxiredoxin (EC 1.11.1.15) (Q88NW9)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Interaction partners:
- DNA-binding stress protein
- Thioredoxin reductase
- Glutaredoxin
- Alkyl hydroperoxide reductase subunit F
- Glutathione-dependent peroxiredoxin
- N-methylproline demethylase
Sequence:
MSVLVGKKAPDFTVPAVLGNGEIVDSFNLASAIKGKYGLVFFYPLDFTFVCPSELIALDNRIPDFQARNVEVIGVSIDSHFTHNAWRNTPVNNGGIGQVKYTLAADMTHEICKAYDVESEGGVAFRGAFLIDTNGVVRSQIVNDLPLGRNMDELLRLVDALQFHEEHGEVCPANWKKGDKGMNASPEGVAAYLSENAGKL
Protein: Beag (LD21347p) (Q9VHH8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- WD40 repeat-containing protein SMU1
- Mst85C, isoform A
- Pre-mRNA-processing factor 6
- Microfibrillar-associated protein 1
- 116 kDa U5 small nuclear ribonucleoprotein component
- RE15976p
- WD repeat-containing protein 55 homolog
- Splicing factor 3B subunit 3
- Pre-mRNA-splicing factor 38
- U5 small nuclear ribonucleoprotein 40 kDa protein
Sequence:
MSDAHLEAPPSVRLTNDDFRKLLATPRAPPPGSGTSSTSAGGSLATATFATPSTAPGTTGLSGEKKKGQSSSERNDLRRKKKNFYAALKKQEDVKLQELSEKYRDRARERRDGANPDYVNVSTPGHGSSTNAYRAVAPDMKSGIDAQERRRRIIQESKFLGGDIQHTHLVKGLDYALLQKVRSELHSKEAEEEEIAAAVAREKLAEAAAAAEQLEAERRESEDINAINGALARNIYNLVQARRSKEVPRNELFAPGRMAYVIDLDDELGESDIPTTLKRSKFEVPVSQEDVATLTTNDIVINKLSQILSYLRAGGRNKKNKKRDKDKPLFYEKEVENLRGSSSNGGSSRHATSSSSNMGGKSAPLGDNIYDDIGDYQPSATRPERNRQEQGKSAPSYFGDGPPEASEEPIISSIPPPPKISKAMAARFAEPEGYAECYPGLEEMNDAIDDSDDEVDYTKMDLGNKKGPIGRWDFDTQEEYSDYMSTKEALPKAAFQYGVKMQDGRKTRKNKTEKNEKAELDREWQKIQTIIQKRKLPKDGGGGGAGGDEPDYKSAKY
Protein: POC1 centriolar protein homolog B (WD repeat domain 51B) (A2CEH0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q8TC44}.
Interaction partners:
- Protein FAM161A
- Centrosome and spindle pole-associated protein 1a.
- Centrosomal protein POC5
- Serine/threonine-protein kinase PLK4
- Spindle assembly abnormal protein 6 homolog
- Centrosomal protein of 135 kDa
- Single-strand DNA endonuclease ASTE1
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Retinoblastoma-binding protein 5.
- Centrin, EF-hand protein, 2
Sequence:
MASVMEDPTLERHFKGHKDVISCADFNPNNKQLATGSCDKSLMIWNLAPKARAFRFVGHTDVITGVNFAPSGSLVASSSRDQTVRLWTPSIKGESTVFKAHTASVRSVHFSRDGQRLVTASDDKSVKVWGVERKKFLYSLNRHTNWVRCARFSPDGRLIASCGDDRTVRLWDTSSHQCINIFTDYGGSATFVDFNSSGTCIASSGADNTIKIWDIRTNKLIQHYKVHNAGVNCFSFHPSGNYLISGSSDSTIKILDLLEGRLIYTLHGHKGPVLTVTFSRDGDLFASGGADSQVLMWKTNFDSLNYRELLSKHSKRVTPDPPPHLMDIYPRSHHRHHPQNGTVEINPVADTQSTDPQVVEVGRVVFSTTDARNYDGASSSRAQFTSGMDSGPFRTHTQAREEEDENQEERFAGGMTASPAERSGIPSSLTSTLENIVQQLDILTQTVAVLEERLTLTEDKLRTCLDNQVLLMQQNQQLDRSDEESEGPPL
Protein: Tudor domain-containing protein 7 (PCTAIRE2-binding protein) (Tudor repeat associator with PCTAIRE-2) (Trap) (Q8K1H1)
Organism: Mus musculus (Mouse)
Function: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11527406, ECO:0000269|PubMed:17141210, ECO:0000269|PubMed:21436445}. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids.
Interaction partners:
- ATP-dependent RNA helicase TDRD9
- Piwi-like protein 2
- Dead end protein homolog 1
- Piwi-like protein 4
- Nanos homolog 1
Sequence:
MLEADLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVVRIEASRSGEIVCYAVACTETARIAQLVARQRTSKRKIGRQINCQMRVKKAMPFFLEGKPKATLRQPGFASDYSISRKPNSALLRDRGSALGVKADVDMPPYPDTPVQRHASMSANSRFSPKSSLPASFQTHISRACPTEVNDNLNQTVEKPNITPPASYTNKMDEVQNRIKEILDKHNNGIWISKLPHFYKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGGQDSLLYPARREQPLKSDQDPEKELPPPPPAPKQEVPSQGSPAVMPDVKEKVAELLGKYSSGLWASALPKAFEDMYKVKFPEDALKNLASLSDVCTINYISGNTQKAILYAKLPLPTDKILKDEGQAQGDFDIKSMIEQEYLQIEKNMAESADEFLEDITVPPLVIPTEASPSVLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEFYSKNPRVTPIQTVHVGQLLAVNAEEDAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSFQATKCKLAGLEVLNDDPDLVKAVESLTCGKIFAVEILDKSDVPLVVLYDTSGEDDININATCLKAICDRSLQVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKMDETKGVAYVYLFTPNNFPDPHRSINRQITNADLWKHQKDVFLSAVSTAASSPGNRNGGTPAPGSPAESLRKSHPEVIKKSVLDHTSSFSLEELPPPVHLSRSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVERDQVYAAKVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDVFRKLPFQAVTAQLAGVKCSQWSEEASMVFRNHVEKKALVALVQTVVEHTNPWDRKVVLYLVDTSLPDTDTWIHDFMSQYLLELSKVN
Protein: Prolyl-tRNA editing protein ProX (Prolyl-tRNA deacylase ProX) (Q9L4Q7)
Organism: Acetoanaerobium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / CCUG 9281 / NCIMB 10654 / HF) (Clostridium sticklandii)
Function: Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro). Has weak activity on correctly charged tRNA(Ala), tRNA(Gly) as well as tRNA(Cys), tRNA(Met), tRNA(Pro), tRNA(Ser) and tRNA(Leu).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Proline--tRNA ligase
- 5'-deoxynucleotidase
Sequence:
MDMDAKQAVIAKLDELKINYTLIEHDPVYTIEEMEKIDIENVDYIVKNLFLRDAKGRQHYLVVADKDQKIDLKTLQDKIGSTKLSFASEDRLQKYLKLTKGAVSPFGVLNDETAEVEVVFDKNLVGRSCVAVHPNDNSATVVLSYEDLEKIVKANGNTFKAIEL
Protein: Heat shock factor protein 4 (HSF 4) (mHSF4) (Heat shock transcription factor 4) (HSTF 4) (Q9R0L1)
Organism: Mus musculus (Mouse)
Function: Heat-shock transcription factor that specifically binds heat shock promoter elements (HSE) (By similarity). Required for denucleation and organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light (By similarity). In this process, may regulate denucleation of lens fiber cells in part by activating DNASE2B transcription (By similarity). May be involved in DNA repair through the transcriptional regulation of RAD51 (By similarity). May up-regulate p53/TP53 protein in eye lens fiber cells, possibly through protein stabilization (By similarity). In the eye lens, controls the expression of alpha-crystallin B chain/CRYAB and consequently may be involved in the regulation of lysosomal acidification.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9ULV5}.
Interaction partners:
- Phakinin
- Alpha-crystallin A chain
- Gamma-crystallin S
- Gamma-crystallin D
- Gap junction alpha-8 protein
- Filensin
- Beta-crystallin B1
- Beta-crystallin B3
- Beta-crystallin B2
- Gamma-crystallin C
Sequence:
MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDSRWRPEDLSRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGAKRKLSLMLDEGSACSASAKFNACPVSGALLQDPYFIQSPLPETTLGLSPHRARGPIISDIPEDSPSPEGHRLSPSGGCRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPMLLRPAPETLEPVAPVDVLGPSLHGREWTLMDLDMELSLMQPLAPETDEAELTVKELNSSGVGKDHTLGTPLMLDVQADLEGAALSVPGALTLYNVTESNASYLDPGASPSSP
Protein: Zyxin (A0A8I6AV84)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MAAPRPPPAISVSVSAPAFYAPQKKFAPVVAPKPKVNPFRPGDSESPVAAGAQRAQMGRVGEIPPPPPEDFPLPPPPVIGEGDDSEGALGGAFPPPPPPLIEEPFPPAPLEEDIFPSPPPPLEEEGGPEAPTQLPPQVSSGYVPPPVATPFVPKPSTKPAPVGTAPLPPWKAPSSSQPPPQPQAKPQVQLHAQPQAKPHVQPQSVSSANTQPRGPLSQAPTPAPKFAPVAPKFTPVASKFSPGAPSGPGPQPSQKSVPLEAPSSVGTGSPQPPSFTYAQQKEKPLVQEKQHPLPPPAQNQNQVRSPGGPGPLTLKEVEELEQLTQQLMQDMEHPQRQSVAVNESCGKCSQPLARAQPAVRALGQLFHITCFTCHQCQQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGQPITDRMLRATGKAYHPHCFTCVVCACPLEGTSFIVDQANQPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKALSIEADDNGCFPLDGHVLCRKCHSARAQT
Protein: Death domain associated protein (Q4VX54)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQS
Protein: Ankyrin repeat protein (Q83F76)
Organism: Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Interaction partners:
- Uncharacterized protein
- Hypothetical cytosolic protein
- Uncharacterized protein
- GIY-YIG domain-containing protein
Sequence:
MQLAAREGRVAMVEWLVRQGLSLEYSDPTRNLVLIAATHERLNLLKWLEEKGLSLDVRDQNGNDPVLLASANRDVLMLEWLVLEKELPLDSQNDQKLTALNHAVGKKYSNDFDNRHLATVLFIVDKLLRQGINLDCEGWSLLSWKMRASWLRSLAHQLNQDGFYEQAEIIYDIIWKKLETGEEKEKLGYQLASLILAGSSEQQEKIKIQKVLRTKNEKAASKSTMEEALSLDEDETNKPPKTQEEAFASLLSEENLCLFASTLKTEDSVHRTLNEKIALQRRAARALSYIMENKDDASLELKGRLIENLKGNFSLQQAEGKEEKEKTYQPQTPIAAAHFLNNPPSSLSPPNLAEFYRLHLGDQLVQMQRILERNAELEEECRLKSGQQDENNYSGPGLF
Protein: P2X purinoceptor 5 (P2X5) (Q91VE2)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q93086}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P56373}.
Interaction partners:
Sequence:
MGQAAWKGFVLSLFDYKTAKFVVAKSKKVGLLYRVLQLTILLYLLIWVFLIKKSYQDIDTSLQSAVVTKVKGVAYTNTTMLGERLWDVADFVIPSQGENVFFVVTNLIVTPNQRQGICAEREGIPDGECSEDTDCHAGESVVAGHGLKTGRCLRVGNSTRGTCEIFAWCPVETKSMPTDPLLKDAEGFTIFIKNFIRFPKFNFSKANVLETGNKHFLKTCHFSSTNLYCPIFRLGSIVRWAGADFQDIALKGGVIGIHIEWDCDLDKAASHCNPHYYFNRLDNKHTQSISSGYNFRFARYYRDPHGVEFRDLMKAYGIRFDVIVNGKAGKFSIIPTVINIGSGLALMGAGAFFCDLVLIYLIRKSEFYRDKKFEKVRGQKEEDNVEVEANEMEQELPEDKPLERVHQDEQALELAQSGRKQNSNCQVLFEPARSGLQENAFVNMKPSQILQTVKT
Protein: GATOR2 complex protein WDR24 (Q86BR7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPDSVEDTSTISLRICLEGHANALALNKDNNQIALAGRSLLKVYSINSNGFTESCNMRGKNQNLSYSANDVAWSTLDSNLLATAATNGVVSVWDLSKFGRQKQLLVYNEHERTAHTVTFHSSEPNILISGSQDGTIKCFDIRSDKSINTYFCNSESVRDVKFSPHTQNIFSAVSENGTVQLWDMRKWDKCMVQFTAHYGPVYTCDWHPTRNWLATGSRDKQIKVWNMDGRPGLEHTIHTIAVVGRVKWRPERTYHIASCALVVDYSVHVWDIRRPYIPFASFNEHTNVTTGIAWQGSDSHCLLSISKDSTIYKHAFKDATRPALKANAQGASLGRFGDISFANKIKEYEPKTSGASNTKSSSFISRRKTNVAGSIQFHLDHSKMYKFMVNDTFSGYPLSESVSRPTQEHESFIGCARELVISGKKLSELCEHNAEVSKKYGKHNATTLWNFIKLFYGSNHFEPPFEHRSSFSNQKNPMNSRRATQVASDWPQQRTELGQDLNGNTPETAHEIDVANVDDDTLGSSGVEHPPTSSVILSETQIISEITFDNFELLRNGFIYVGPTECPKALAFPALHHDVQAARPQLDLKASDHEKSPPPHVPTVLKVSHVPPIPMWEPHKFVSDALMLMNDVGDVQTALTVLIALGEARKLLPIDDALVEHWFYTYVDQLHRYELWNEACEVINRSWLRSVQQLNQHSTAMHTNCGECGRPMGGKVGWYCDKCKSMQSAKCCVCGLIVRGVYAWCQGCSHGGHIEHLQKYFAKHSKCPKCGHLCAYS
Protein: Coiled-coil domain-containing protein 24 (Q8N4L8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLRHSPSLWELVEEHVPLRERREVKRILGEAAVDLSLELRAEVAMLRALLQEARSSQAPSSRPISDPSSLLAPPPLLKDLLRQELRQLLQGLRHKAICEGRDQAQAWVQYSPRVLHFALEEPRCDLPEQEIFQMRGGGPSSGHRDLSIIKDQLNVSNIDQVARHLRGLLEEECHTLEREILILQRCLEEEYLRPCHPSEAALEPTLAELKEQKKAMEQELQASVGPSCVSPNHRQRPLGSSTQGLRPPLPLCGVAPLQCCLPAPPLEPYLRPRGQSATHRWGRQLQCSPREGPASTPMSSAAPQAPA
Protein: Cytochrome b559 subunit beta (PSII reaction center subunit VI) (P62095)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00643}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00643}.
Interaction partners:
- Photosystem II D2 protein
- Photosystem II reaction center protein J
- Expressed protein
- Photosystem II reaction center protein Z
- Photosystem II reaction center protein K
- Photosystem II reaction center protein I
- Photosystem II reaction center protein L
- Oxygen-evolving enhancer protein 1-1, chloroplastic
- Photosystem II CP43 reaction center protein
- Photosystem II CP47 reaction center protein
Sequence:
MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
Protein: Zinc finger protein 2, putative (Q57WV5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Polyubiquitin, putative
Sequence:
MQGYFAVNPPLLPAGWQIAYTANGQPYYLDHNTKTTHWNLPETVGYSFGGYYDPVMVAGGNRGGRGGRGGRNGIDQGKRKTKMCIYWEKNGECSWGDRCAFAHGPGELRASVGPDSSQMQQVGHDVPPMA
Protein: Novel opsin (Parapinopsin b) (Q8JFR3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}.
Interaction partners:
Sequence:
MDFFPEFLNDSSTHYDGPGLKVPLPRAGFITLSLLMAVFSITSVVLNATVIVVTLRHKQLRQPLNFALVNLAVADLGTTLTGSVPSVVTNAVGYYIMGRIGCVLEGFCVAFFGISALCTVALIAVERLFVVCRPLGSITFQCRHAAGGLLSCWLWSLIWNTPPLLGWGSYQLEGAGTSCGPHWQSRELRDVSYIICYFSVCFAVPFAIILVSYSWLLYTLRQVLLEMVNNLGTFGMLFSAYYDLGHIFKHYKHCNAALTLVLFFVVEYHWLPYAALALTVVSKPEVQLAVLVKVLPIYMAKSSTVYNPLIYIYMNKQVSRTS
Protein: Mitogen-activated protein kinase 12 (AtMPK12) (MAP kinase 12) (EC 2.7.11.24) (Q8GYQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Negative regulator of the auxin transduction signaling pathway. Involved in stomatal movement regulation by phosphorylating and repressing HT1 and HT1-mediated GHR1 phosphorylation. Required for CO(2)-mediated stomatal movements (e.g. closure).
Subcellular location: Nucleus {ECO:0000269|PubMed:19000167}. Cell membrane {ECO:0000269|PubMed:27923039}; Peripheral membrane protein {ECO:0000269|PubMed:27923039}; Cytoplasmic side {ECO:0000269|PubMed:27923039}. Note=Seems to translocate at the plasma membrane upon interaction with HT1. {ECO:0000269|PubMed:27923039}.
Interaction partners:
- Protein-tyrosine-phosphatase IBR5
- Mitogen-activated protein kinase kinase 6
- Dual specificity protein phosphatase 1B
- Dual specificity protein phosphatase 1
- Protein-tyrosine-phosphatase PTP1
- Protein-tyrosine-phosphatase MKP1
- Guard cell S-type anion channel SLAC1
- LRR receptor-like serine/threonine-protein kinase GHR1
- Protein DETOXIFICATION 56
- Mitogen-activated protein kinase kinase 1
Sequence:
MSGESSSGSTEHCIKVVPTHGGRYVQYNVYGQLFEVSRKYVPPIRPIGRGACGIVCAAVNSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLRHMDHENVITIKDIVRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSDQCRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDTDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSSLGFLRSDNARRYVRQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRISVDEALGHAYLSPHHDVAKEPVCSTPFSFDFEHPSCTEEHIKELIYKESVKFNPDH
Protein: Cytochrome b5 reductase like (E9PMD3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MMAEREEDDDTEEAWMQLRPTEPLPSQCCGSGCSPCVFDLYHRDLARWEAAQASKDRSLLRGPESQSCPSKLNPETFVAFCIIAMDRLTKDTYRVRFALPGNSQLGLRPGQHLILRYTQVAGGPKLHSPALLFASCWP
Protein: Origin recognition complex subunit 6 (Q9Y1B2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Origin recognition complex subunit 1
- Cell division control protein
- Origin recognition complex subunit 5
- Origin recognition complex subunit 4
- Origin recognition complex subunit 3
- Origin recognition complex subunit 2
- Double parked, isoform A
- DNA replication licensing factor Mcm7
- DNA replication licensing factor Mcm5
- CDC45L
Sequence:
MTTLIEQLITKMGLREEPNVLEKTTELVRLLELRSTNVPLQINEYGKIVLCADLASCMIGIAFDKEQALKLSGLRKSQYLNNKRMFEKLLDLNKLASVNDICVQLGLNEVARKAEELMTLFKGVAATEDMGTDTSHPQYATMAVFQACRLLKKKVSKSKLMPFSNLRPSQFQLLEQQWERMIAKHHKESKVPSSTDMEGKLKENQNENIKGHEAKKAHKPPPEDYEIWKARMLAKAQAKLKELEASQSHMDSQLLEA
Protein: Probable serine/threonine-protein kinase WNK9 (AtWNK9) (EC 2.7.11.1) (Protein kinase with no lysine 9) (Q2V338)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May regulate flowering time by modulating the photoperiod pathway.
Interaction partners:
- Protein kinase family protein
Sequence:
MMNNLSHLESDYSEYVEVDPTGRYGRYNEVLGKGSSKTVYRGFDEYQGIEVAWNQVKLYDFLQSPQELERLYCEIHLLKTLKHKSIMKFYASWVDTDNRNINFVTEMFTSGTLRQYRLKHKRVNIRAVKNWCRQILRGLNYLHTHDPPVIHRDLKCDNIFINGNQGEVKIGDLGLAACLQHSHAAHCVGTPEFMAPEVYKEEYNQLVDIYSFGMCVLEMVTFDYPYSECSHPAQIYKRVISGKKPDGLDKVKDPEVRGFIEKCLATVSLRLSACELLDDHFLCIDESDMRRVESEKGLIDEAGTPLRHSYHIPHYSNGYYSLYNQNQWDYNGDETVESHEIDLLEFQNDDDEEEEDKRFGSVDISIKGKRRDNGDGLFLRLKTVNKEGCVRNIYFPFDIETDTAISVAREMVEELEMDDRDVTKIANMIDGEIASLVPNWSIFCSSESNRSSVGSVMDFNEMQCGRDGCEEKHGRFEEITFEITVNDSDEED
Protein: Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein) (Q14728)
Organism: Homo sapiens (Human)
Function: Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.
Subcellular location: Nucleus inner membrane {ECO:0000250|UniProtKB:Q9D2V8}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000305|PubMed:18638446}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Serine incorporator 5
- Glycerol-3-phosphate acyltransferase 3
- Glycerol-3-phosphate acyltransferase 4
Sequence:
MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFRDAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
Protein: Opossum, isoform A (Opossum, isoform C) (Q9VXY9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00037847}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00037847}. Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}.
Interaction partners:
- Transmembrane emp24 domain-containing protein bai
- Transmembrane emp24 domain-containing protein eca
- LD24704p
Sequence:
MQAIWLGMPGLVLLLSIAALLLGVQDAEAYDKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGHGDLDISFTLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGEELQGDTQWNEADELTGLSRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESNFQKVNHWSMVQISAMIGVGLIQVFMLRSIFATGGRMHNLWRKLGI
Protein: Mitotic-spindle organizing protein 2A (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A) (Q6P582)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
Interaction partners:
- Mitotic-spindle organizing protein 1
- Gamma-tubulin complex component 2
- Gamma-tubulin complex component 5
- Gamma-tubulin complex component 4
- Protein NEDD1
- Tubulin gamma-1 chain
- CDK5 regulatory subunit-associated protein 2
- Nucleoside diphosphate kinase homolog 7
- Gamma-tubulin complex component 6
- Mitotic spindle organizing protein 2B
Sequence:
MAAQGVGPGPGSAAPPGLEAARQKLALRRKKVLSTEEMELYELAQAAGGGIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQDPAAVSLPTSSVPETRGRDKGSAALGGVLALAERSNHEGSSQRMPRQPSATRLPKGGGPGKSPTQGST
Protein: Histidine triad nucleotide binding protein 1, pseudogene 1 (D4A269)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Zinc finger, HIT-type containing 1
- Cytochrome c oxidase subunit 7C, mitochondrial
- ATP synthase F
Sequence:
MADEIAKAQVAQPGGDTIFGKIIRKEIPAKIIFKDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQMNWPPG