wanglab/gogpt-training-data huggingface dataset:
Protein: Paladin (Q9ULE6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:22354871}.
Interaction partners:
Sequence:
MGTTASTAQQTVSAGTPFEGLQGSGTMDSRHSVSIHSFQSTSLHNSKAKSIIPNKVAPVVITYNCKEEFQIHDELLKAHYTLGRLSDNTPEHYLVQGRYFLVRDVTEKMDVLGTVGSCGAPNFRQVQGGLTVFGMGQPSLSGFRRVLQKLQKDGHRECVIFCVREEPVLFLRADEDFVSYTPRDKQNLHENLQGLGPGVRVESLELAIRKEIHDFAQLSENTYHVYHNTEDLWGEPHAVAIHGEDDLHVTEEVYKRPLFLQPTYRYHRLPLPEQGSPLEAQLDAFVSVLRETPSLLQLRDAHGPPPALVFSCQMGVGRTNLGMVLGTLILLHRSGTTSQPEAAPTQAKPLPMEQFQVIQSFLRMVPQGRRMVEEVDRAITACAELHDLKEVVLENQKKLEGIRPESPAQGSGSRHSVWQRALWSLERYFYLILFNYYLHEQYPLAFALSFSRWLCAHPELYRLPVTLSSAGPVAPRDLIARGSLREDDLVSPDALSTVREMDVANFRRVPRMPIYGTAQPSAKALGSILAYLTDAKRRLRKVVWVSLREEAVLECDGHTYSLRWPGPPVAPDQLETLEAQLKAHLSEPPPGKEGPLTYRFQTCLTMQEVFSQHRRACPGLTYHRIPMPDFCAPREEDFDQLLEALRAALSKDPGTGFVFSCLSGQGRTTTAMVVAVLAFWHIQGFPEVGEEELVSVPDAKFTKGEFQVVMKVVQLLPDGHRVKKEVDAALDTVSETMTPMHYHLREIIICTYRQAKAAKEAQEMRRLQLRSLQYLERYVCLILFNAYLHLEKADSWQRPFSTWMQEVASKAGIYEILNELGFPELESGEDQPFSRLRYRWQEQSCSLEPSAPEDLL
Protein: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (BPG-independent PGAM) (Phosphoglyceromutase) (iPGM) (EC 5.4.2.12) (Vegetative protein 107) (VEG107) (P39773)
Organism: Bacillus subtilis (strain 168)
Function: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Interaction partners:
- Phosphoglycerate kinase
- Enolase
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase 1
- Probable fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Pyruvate kinase
- Glycerate kinase
- D-3-phosphoglycerate dehydrogenase
- Uncharacterized protein YvyF
Sequence:
MSKKPAALIILDGFGLRNETVGNAVALAKKPNFDRYWNQYPHQTLTASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAISNAKENNKALHLFGLLSDGGVHSHINHLFALLKLAKKEGLTKVYIHGFLDGRDVGPQTAKTYINQLNDQIKEIGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRSALDVVDDSYANGIYDEFVIPSVITKENGEPVAKIQDGDSVIFYNFRPDRAIQISNTFTNKDFRDFDRGENYPKNLYFVCLTHFSETVDGYVAFKPINLDNTVGEVLSQHGLKQLRIAETEKYPHVTFFMSGGREAEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIEADKHDAIILNFANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAILAKGGHAIITADHGNADILITESGEPHTAHTTNPVPVIVTKEGITLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQK
Protein: Phage shock protein A (Q726W8)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Phage shock protein C
- Psp operon transcriptional activator
- histidine kinase
- histidine kinase
- Sensory/regulatory protein RpfC
- histidine kinase
- Sensory/regulatory protein RpfC
Sequence:
MGIFSRFKDIVSSNINAMLDRAEDPEKLIRLMIREMEETLVELKAACARTMAECRRLGREGEEAERQVSLWDRRAELALDSGREDLAREALLERRRATEHVEALTRETEECEALVARTQEDMDVLEQKLVTAREKQRLLAQRHVHARARRQAREESRRAASFDVMERFETMERRVEHMEAEADAVRVPRSGGAGGVFADLETRDAIERDLAALRQRMGRDG
Protein: TBC1 domain family member 24 (Q9ULP9)
Organism: Homo sapiens (Human)
Function: May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function. Involved in the regulation of synaptic vesicle trafficking.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20727515}; Peripheral membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:20727515}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9VIH7}. Presynapse {ECO:0000269|PubMed:31257402}. Note=Mainly cytoplasmic with partial expression at the plasma membrane (PubMed:20727515). Associates with certain types of membrane phosphoinositides, preferentially those phosphorylated at the D5 position of the inositol ring such as phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity). {ECO:0000250|UniProtKB:Q9VIH7, ECO:0000269|PubMed:20727515}.
Interaction partners:
- ADP-ribosylation factor 6
- Ras-related protein Rab-35
Sequence:
MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEIQLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCSENFLIAAVEAWGFQDPDTQ
Protein: Rifin (Q8IBE3)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKVHYINILLFALPLNILVKLCRVHYQRNHKSPIPHKEKIHRILCECDLYTSIYYNDPEMNSVMQQFDLQTSKRFEEYDEWMKEKRIQCKEKCDKEIQNIILKDKIEKDLKDKFGALQTDLDSDAIPTCVCEKSVADKTEKFCLNCGKNMGAITPCWGLVSGLGYYRWEIAATAAAVQKGIDAGIAKAIELLKQNFGLTSLTNDAWTNLVNAKTFKDSAVLNSSLKELGEKICIFRDGTYDGDPMCMFMEKGPFKFAEITRKHTETVATKAAAEATSVTDANVAEVTASGFTYSTAITASIVAIVVIILVMLIIYFILRYRRKKKITKKLQYIKLLKE
Protein: IAA-alanine resistance protein 1 (Q9M647)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May participate in auxin metabolism or response. Probable transporter.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative zinc transporter At3g08650
- Zinc transporter 7
- Zinc transporter 3
- Metal tolerance protein 1
- Metal tolerance protein C2
- Probable zinc transporter 10
- Metal tolerance protein 11
- Zinc transporter 9
- Zinc transporter ZTP29
- IAA-leucine resistant 2
Sequence:
MSFSLRKLLVPILVLVLFLDLCVESGFSQSTPARDDHVHHHGGGCSHSHDHDHDHDHDHHVKKTTAKVEMKLPEELAEEEDMRLCGFGPCLHDHDHESSSTLTGFALWLNALGCSLLVSLASLICLVLLPIMFVQGKPSKWFVDSLALFGAGAMLGDAFLHQLPHAFGGGHSHSNDHHENHDHHDHSHSDSPSHSHSIQDLSVGLSVLAGIVVFLLVEKLVRYVEENSSGSNTWGHHHHHHHAGSKKLKDEGDHNNLDQQSSSDAIVNSSEKVSGGSTDKSLRKRKTSASDATDKSDSGTEITSDGKSDKPEQVETRSSSLVFGYLNLFSDGVHNFTDGMALGSAFLIYGSVGGWSRTMFLLAHELPQEIGDFGILVRSGFTVTKALFFNFLSALVALAGTALVLVWGNEPGQSSLIEGFTAGGFIYIAVAGVLAEMNNSGKSTLKNSACHLISLILGMSVALCISLIE
Protein: Sushi repeat-containing protein SRPX (P78539)
Organism: Homo sapiens (Human)
Function: May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction.
Subcellular location: Cell surface {ECO:0000305}. Note=Possibly surface of photoreceptor cell.
Interaction partners:
- Bombesin receptor subtype-3
Sequence:
MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPIKVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT
Protein: Scaffold protein ILK (ILK-1) (ILK-2) (Inactive integrin-linked kinase) (p59ILK) (Q99J82)
Organism: Rattus norvegicus (Rat)
Function: Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Regulates cell motility by forming a complex with PARVB. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Subcellular location: Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q13418}. Cell membrane {ECO:0000250|UniProtKB:Q13418}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q13418}; Cytoplasmic side {ECO:0000250|UniProtKB:Q13418}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:O55222}. Cytoplasm, myofibril, sarcomere {ECO:0000250|UniProtKB:Q13418}. Cytoplasm {ECO:0000250|UniProtKB:Q13418}. Nucleus {ECO:0000250|UniProtKB:Q13418}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q13418}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q13418}.
Interaction partners:
- Alpha-parvin
- LIM and senescent cell antigen-like-containing domain protein
- Parvin, beta
- Paxillin
- Gamma-parvin
- Integrin beta-1
- RAC-alpha serine/threonine-protein kinase
- Talin 1
- Talin 2
- FERM domain containing kindlin 2
Sequence:
MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQAPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
Protein: Cysteine rich hydrophobic domain 2 (H0Y8H1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
Protein: Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Hit family protein 2) (P49775)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.
Subcellular location: Cytoplasm. Nucleus. Mitochondrion {ECO:0000269|PubMed:16823961}.
Interaction partners:
- Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2
- Protein APA1
- Deaminated glutathione amidase
- Omega-amidase NIT3
- Ferrochelatase, mitochondrial
Sequence:
MNKPIYFSKFLVTEQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINNVGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL
Protein: Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92) (Q8VII6)
Organism: Rattus norvegicus (Rat)
Function: Probable choline transporter. May be involved in membrane synthesis and myelin production.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19236841}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000269|PubMed:19236841}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- High affinity choline transporter 1
- Solute carrier family 22 member 2
- Solute carrier family 22 member 1
- Solute carrier family 22 member 3
- Choline transporter-like protein 2
- Choline transporter-like protein 4
- Choline transporter-like protein
- Choline transporter-like protein 3
Sequence:
MGCCSSASAAQSSKREWKPLEDRSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQRNAKLEAIANSGLDHTHRKYVFFLDPCNLDLINRKIKSMALCVAACPRQELKTLSDVQKFAEINGSALCSYNIKPSEYTLTAKSSAFCPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVIPEQLQIAEDNLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFLGTTGSAVQNEQGFVEYKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKENACARCMLKSCICCLWCLEKCLSYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKAMKEAGKGGAADARKLKPMASGASSA
Protein: Forkhead box protein F2 (Forkhead-related activator 2) (FREAC-2) (Forkhead-related protein FKHL6) (Forkhead-related transcription factor 2) (Q12947)
Organism: Homo sapiens (Human)
Function: Probable transcription activator for a number of lung-specific genes. Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1.
Subcellular location: Nucleus {ECO:0000269|PubMed:29374064, ECO:0000269|PubMed:9799607}.
Interaction partners:
- GDP-mannose 4,6 dehydratase
- Forkhead box protein F1
Sequence:
MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAAAAAAAAAPETTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGCHSQGGYGGLDMMPAGYDAGAGAPSHAHPHHHHHHHVPHMSPNPGSTYMASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPVPSSPAMASAIECHSPYTSPAAHWSSPGASPYLKQPPALTPSSNPAASAGLHSSMSSYSLEQSYLHQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDIKPCVM
Protein: Regulating synaptic membrane exocytosis protein 3 (Nim3) (RIM3 gamma) (Rab-3-interacting molecule 3) (RIM 3) (Q9JIR3)
Organism: Rattus norvegicus (Rat)
Function: Regulates synaptic membrane exocytosis.
Subcellular location: Synapse {ECO:0000250}.
Interaction partners:
- Interleukin-1 receptor accessory protein-like 1
Sequence:
MFNGEPGPASAGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSEGTFIFPTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKAYLLENGACVAKKKTKVAKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAVVTGWYKFFPTSSVADSTLGSLTRRLSQSSLESATSPSCS
Protein: Signal transducer and activator of transcription (B3DGV1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
- Interferon regulatory factor 9.
- Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase.
- Tyrosine-protein kinase
- Tyrosine-protein kinase
- Tyrosine-protein kinase.
- Interleukin 13
- Interleukin family protein
- Transcription factor GATA-3
- T-box 21 like
Sequence:
MAQWAQMTQHIQFLTTEVLNELYPVTFPLDIRHYLASWIEGQQWDSFDVDNREQESQAQLLSDQMVMLLHQVAKQNPNVVEKVKLQHMSKNWSVLYPQPLQLVRTVREILRKERLILSQTNMQFPPFAPPPTNGIPQQAWEEKKTDVENLMSKVMEIQNRRQTLHQLQEELNWEKETIQGLSEMDTGAKQKRIQQIEYNATICAQERVQFLCDAVGALEQCQSSLMLKIESWRWEQHRSTIGMPFNDILDHLQTWSEQLLIVNGNLRQELMLMKVDHGDAERLRTLEENLARLLKTLIQNSLVVEKQPPQVIKTQSKFSTTVRYLLGDKMAPGKPVLLKAQIITEAQARNLGQQSVIPNENVGELLNSTTILEHNTTSKNTCATFRNMSIRRIKRADRKGSESVTEEKFALLFTTDITITGGERPYSLQSISLPVVVIVHGSQEINAMATIIWDCAFSEPNRIPFLVPERVSWQQMCGALSSKFMSEVQTTRGLDPLNLRFLGQKIFDQPDHPGDFENMLVSWAQFNKEVLPGRNFTFWQWFEGAIDLTKRCLRDYWTDGLIFGFIGKQYIHCMLQDKTNGFFLLRFSDSEIGGITIAYVEPTENGGRRVQNIQPFTKKDLDSAGLGDRIRDISCISHVYPGIPKNEAFKKYFTVPSAPNADGYLPFKLTTVVNPGDNSTSTNNITSENISMNFISPSTSQAFGQNMNQDIYNQHCTPSYSMPDDIMPPQPMYPTDMQVNPPDEFSEMEEFEGLLSSI
Protein: Uncharacterized protein (Q585W6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEHLPTIDSRVETLRLVFGSFLRLIIYSVTYYTGRGLFSQYVLRRRGSVSQSKQSMISYVASQGLEIGVSVIICPVRYLAAVTTPRFLFDYTLTGWSEILRTLDLFSPGRFASYAVYAFSSTSEWDLDFFVWQMPSVALTLAKLWYRRRHLGTKKCCTTRVLLMLPLQILLRAYLSSFSVMIPECGEELLEAIVSAGLEAGVSAYIIRNTSPFVEENNKLRLVGTLKHHSIGSQAGEREDANKKQE
Protein: ATP synthase subunit H, mitochondrial (Q12349)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Subcellular location: Mitochondrion. Mitochondrion inner membrane.
Interaction partners:
- ATP synthase subunit 4
- ATP synthase subunit 9, mitochondrial
- ATP synthase subunit J, mitochondrial
- ATP synthase subunit a
- ATP synthase subunit beta, mitochondrial
- ATP synthase subunit gamma, mitochondrial
- ATP synthase subunit f
- ATP synthase subunit alpha
- ATP synthase subunit delta, mitochondrial
- ATP synthase subunit 5, mitochondrial
Sequence:
MFPIASRRILLNASVLPLRLCNRNFTTTRISYNVIQDLYLRELKDTKLAPSTLQDAEGNVKPWNPPQKPNLPELELQGPEALKAYTEQNVETAHVAKESEEGESEPIEEDWLVLDDAEETKESH
Protein: All-trans retinoic acid-induced differentiation factor (Apoptosis-related protein 3) (APR-3) (Q6PGD0)
Organism: Mus musculus (Mouse)
Function: Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway (By similarity).
Subcellular location: Nucleus envelope {ECO:0000250|UniProtKB:Q6UW56}. Cell membrane {ECO:0000250|UniProtKB:Q6UW56}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q6UW56}. Lysosome membrane {ECO:0000269|PubMed:29745899}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with NELL1 on the nuclear envelope and the perinuclear region. {ECO:0000250|UniProtKB:Q6UW56}.
Interaction partners:
Sequence:
MASRESGGSRAAALLLVLGVERALALPEICTLCPGGMHNLSRVAAYCEDTSKLMQARCCLNQKGTILGLDLQNCSLKDPGPNFLQAYTAIIIDLQANPLKDDLANTFRGFTQLQTLILPQDVPCPGGSNAWDNVTSFKDKQICQGQRDLCNSTGSPEMCPENGSCASDGPGLLQCVCADGFHGYKCMRQGSFSLLMFFGILGSTTLAISILLWGTQRRKAKAS
Protein: Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2) (P68306)
Organism: Gallus gallus (Chicken)
Function: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Subcellular location: Nucleus.
Interaction partners:
- Thyroid hormone receptor alpha.
- Retinoic acid receptor RXR-gamma
Sequence:
MSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYEGKCVIDKVTRNQCQECRFKKCIFVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKTIGHKPEPTDEEWELIKIVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLVCVERIEKCQEGFLLAFEHYINYRKHHVAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
Protein: Ecm29p (A0A1D8PKU7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Proteasome regulatory particle lid subunit
- 26S proteasome regulatory subunit 6A
- Proteasome regulatory particle lid subunit
- 26S proteasome regulatory subunit RPN2
- Proteasome regulatory particle base subunit
- Proteasome regulatory particle lid subunit
- Proteasome regulatory particle lid subunit
- Proteasome regulatory particle base subunit
- 26S proteasome regulatory subunit 8 homolog
- 26S proteasome regulatory subunit RPN8
Sequence:
MQMLVLANSSFRLNSFFSLCCKTKILPLFLLLPKTPKNNQNFSLLMSSQELALVNKVELRIALAENDKQFENALNIYLAPVLLKLASPHIEVRQAVLKIIQHIVPRITAARTIKLPVEALIQQIKTPNVETDPTSVRLYSALFVSRGVDRLNEEEKKQLIPTIIEGLHNYPNSISARIFNIICKLLQNWKMPMKGTDEYDNMRRFLQLDKNPIDEQYLSLLISKFLLLLPESTNKATPGLSVQDNAFFTTDAAVTYKTRDDIFQVKNNLLEFLKSGFIPEQIALPLLIASADPSSSINEPSEIAFRKLGVDFDSIIVYDNISFIDYIISLFLGTNAPAVDSNLQCKILQVLIKSHKVHSQDKIASAALGSDNSRLRSLAIQFIRKLGQSPVPEENLEKFNEDIAHQLRNSIIAEGWPCVEVSMGTNYSNKIKDVNSKYEALGEILKSQPSIFFNDWSFLEFLFDSLGATNQSPELTPSIQQALSGLTVHLSSLSDSRKIELKSLLRKYITIDSAKYIVVKYVNSTYPFQDPEARYLSILGTSKTHAPHTIEEGLNGLHPYWFNINQAGNTTEFKSTSYLLGQESSVEFPSFESFIATLSTEIENAKTSHDNAIFLSLPKAIGFAEQVLVMNAVKDKTTVIACDQDWSIRLEKAIEMNDTVRNLIIAKMQNPTVQESVFKLLSICVDAVTGQFDNSTSITTDTSYGLILARLLSSAFSTAVEALIPKSQDLLRLVDADVLDDISLARVCKSFAIIASHPGVSDEDVGSLLNQLIANATYKKSKGRLLAASYLISRIVLRNRLQVIPTSVLTSILQMLETMLSESGFYYSALDAISQLAMFGVLGPIVNQDLSSFVDRFKDIIRAKVKKIDERSVIAFGYLTLTGKTGSDSESLSDDEQIIFNTHVSKQVEYLFTSGEALVVAAAGWNSKLLSKQLDIPDATVEYIPHDTSRVAALLNNILAACRNTQPSLRKAGCIWLLSLVQYCNNLDAVRSKAAEIHVAFMRFLADRDELVQESASRGLGLVYEMGDFDLKETLVKSLLKSFTQSNTSSFTSGSVEHDTELFEPDLLRTNEGSVSTYKDVLNLAQDVGDPSLVYKFMSLAKSSSLWSSRKGIAFGLESILAQSSLDKLLTDNQQLADRLIPKLFRYRYDPNVGVSTSMNDIWNALIKDTSKAVDANFDKILKELLTSMGKKEWRTRQGSTAAMNDLLQMVELNKYQSKLDDIWTMSFRVMDDIKESVRKEGTNLTKSLATKLTRLLETNSNASTNTKSILSFLIPFLLGSKGLLSDSQEVKDFALETVLKLCKSGNKSMKEYVPELIENFINLFSSLEPEVVNYLVLNASKYNVDHNEIDAKRMKSVGHSPLMDAIEKLLNQLDDLLLPDFITRLERTIKKGVGLPTKVSAAMVIMNMVTHHLHMVKPYGDRLLVVAMTQINDRNDTVASSYAAACGHLCRIAKVETVIKYSNKITKMYFEATDAGDERSRVLASVASESVSKYSGDKFETVASAFLPVAYIGRFDPSKEVVENFEREWIENTSGGNSAIKLYLVEIIDLVKKYLKSNDFLIRKTLAKALSNLCLVIDNLNQFSITIIDEILKLLIESNKGKSWDGKELVFDSLVSFAIMSKTYIAHHQDIYEAINKTVTVEIKRRNKAYQKHAIVSCGKYIHHFHEDDELVDLYIEIMTNVLSDRYDSTDDDSDEEMDDEGDTRKLNAKENIELEEKKLKILNNVAVAFYTQPDINNQLFEFVFDRLVKIFQSQFIENTWRSKLETTEIFKKVLTEIEDSGKQVNANLLISTWEFLKQKCLTVDSIENVKIQFIRLSKQLNLYLNKVHQTSTIIDALEEFSRTENSNVVLTELRKTT
Protein: TBC1 domain family member 22B (Q9NU19)
Organism: Homo sapiens (Human)
Function: May act as a GTPase-activating protein for Rab family protein(s).
Interaction partners:
- Protein PROCA1
Sequence:
MAAENSKQFWKRSAKLPGSIQPVYGAQHPPLDPRLTKNFIKERSKVNTVPLKNKKASSFHEFARNTSDAWDIGDDEEEDFSSPSFQTLNSKVALATAAQVLENHSKLRVKPERSQSTTSDVPANYKVIKSSSDAQLSRNSSDTCLRNPLHKQQSLPLRPIIPLVARISDQNASGAPPMTVREKTRLEKFRQLLSSQNTDLDELRKCSWPGVPREVRPITWRLLSGYLPANTERRKLTLQRKREEYFGFIEQYYDSRNEEHHQDTYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSKLLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKEILDEEDFQGLLMLLQNLPTIHWGNEEIGLLLAEAYRLKYMFADAPNHYRR
Protein: Drug ABC transporter ATP-binding protein (A0A100XE85)
Organism: Mycolicibacterium thermoresistibile (Mycobacterium thermoresistibile)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004429}.
Interaction partners:
- Mycobactin import ATP-binding/permease protein IrtA
Sequence:
MIRTLLRLVPAEKRGAVAGYAVLTLLSVLLRAVGAVLLIPLLAALFSDTPSDAWLWLGWLTAVTLAGWVTDTNTARLGFDLGFAVLSRTQHDMADRLPNVAMSWFTPDNTATARQAIAATGPELAGLVVNLLTPLIGAALLPAAIGVALLFVSVPLGLAALAGVAVLFGALALSGRLSRAADKVAGETNSAFTERIIEFARTQQALRAARRVEPARSQVGSALAAQHGAGLRLLTMQIPGQVLFSLAGQVALIGFAGMAVWLTVRGQLGVPEAIALIVVLVRYLEPFAAIADLAPALETTRATLNRIQAVLDAPTLPAGRRRLDRTGAAPSIEFDDVRFSYGDEVVLDGVSFTLRPGNTTAIVGPSGSGKTTILSLIAGLQQPASGRVLLDGVDVTTLDPEARRAAVSVVFQHPYLFDGTLRDNVLVGDPEADPDDVTAAMRLARVDELLDRLPDGDATVVGEGGTALSGGERQRVSIARALLKPAPVLLVDEATSALDNANEAAVVDALTADPRPRTRVIVAHRLASIRHADRVLFVEAGRVVEDGAIDELLAAGGRFAQFWAQQQAASEWAIGSTAR