wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial import inner membrane translocase subunit TIM44 (O35094)
Organism: Rattus norvegicus (Rat)
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:9538267}; Peripheral membrane protein {ECO:0000269|PubMed:9538267}; Matrix side {ECO:0000269|PubMed:9538267}. Mitochondrion matrix {ECO:0000269|PubMed:9538267}.
Interaction partners:
- Stress-70 protein, mitochondrial
- Mitochondrial import inner membrane translocase subunit Tim23
- Mitochondrial import inner membrane translocase subunit TIM16
- Mitochondrial import inner membrane translocase subunit Tim17-A
- GrpE protein homolog 1, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit Tim21
- Mitochondrial import receptor subunit TOM40 homolog
- Heat shock 70 kDa protein 4
- GrpE protein homolog
Sequence:
MAAAALRGGWCRCPRRCLGSGIQFLSSHNLPRGGSSYQISRPGGELTLTKSYSSGSRKGFLSGLLDNIKQELAQNKEMKESIKKFRDEAKKLEESDALQEARRKYKTIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLGRKIKEGVEEAARTAKQSAESVSKGGEKLGKTAAFKAISQGVESVKKEIDESVLGHTGTYRRPERLRKRTEFAGAKFKESKVFEANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMKMKYDESDNVLIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDRFLHQCETDIIPNILEAMISGELDILKDWCYEATYNQLAHSIQQAKALGLQFHSRILDISNVDLAMGKMMEQGPVLIVTFQAQLVMVIKNPKGEVFDGDPDKVLRMLYVWALCRDQEELNPYAAWRLLDISASSTEQIL
Protein: Anthocyanidin-3-O-glucoside rhamnosyltransferase (EC 2.4.1.-) (Anthocyanin rhamnosyl transferase) (Q43716)
Organism: Petunia hybrida (Petunia)
Function: Controls the rhamnosylation of reddish anthocyanidin-3-O-glucosides, which is the first step in a series of modifications that finally yield magenta or blue/purple coloured anthocyanins. Controls the conversion of anthocyanidin-3-O-glucosides to anthocyanidin-3-O-rutinosides.
Interaction partners:
Sequence:
MENEMKHSNDALHVVMFPFFAFGHISPFVQLANKLSSYGVKVSFFTASGNASRVKSMLNSAPTTHIVPLTLPHVEGLPPGAESTAELTPASAELLKVALDLMQPQIKTLLSHLKPHFVLFDFAQEWLPKMANGLGIKTVYYSVVVALSTAFLTCPARVLEPKKYPSLEDMKKPPLGFPQTSVTSVRTFEARDFLYVFKSFHNGPTLYDRIQSGLRGCSAILAKTCSQMEGPYIKYVEAQFNKPVFLIGPVVPDPPSGKLEEKWATWLNKFEGGTVIYCSFGSETFLTDDQVKELALGLEQTGLPFFLVLNFPANVDVSAELNRALPEGFLERVKDKGIIHSGWVQQQNILAHSSVGCYVCHAGFSSVIEALVNDCQVVMLPQKGDQILNAKLVSGDMEAGVEINRRDEDGYFGKEDIKEAVEKVMVDVEKDPGKLIRENQKKWKEFLLNKDIQSKYIGNLVNEMTAMAKVSTT
Protein: Uncharacterized membrane protein At1g16860 (Q9FZ45)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MGSRYPSHQLSNGLFVSGRPEQPKERAPTMSAVAMPYTGGDIKRSGELGKMFDIPADGTKSRKSGPIPGAPSRSGSFAGTAQSGPGAPMATGRMSGSLASAGSVSMKKTNSGPLSKHGEPLKKSSGPQSGGVTRQNSGSIPILPATGLITSGPITSGPLNSSGAPRKVSGPLDSSGLMKSHMPTVVHNQAVTTLGPEDDFSCLKSFPKPVLWLVVLIFIMGFLAGGFILGAVHNPILLVVVAILFTVVAALFIWNICWGRRGITDFIARYPDADLRTAKNGQHVKVTGVVTCGNVPLESSFHRVPRCVYTSTCLYEYRGWGSKPANSSHRHFTWGLRSSERHVVDFYISDFQSGLRALVKTGSGAKVTPLVDDSVVIDFKQGSEQVSPDFVRWLGKKNLTSDDRIMRLKEGYIKEGSTVSVIGVVQRNDNVLMIVPSSEPLAAGWQWRRCTFPTSLEGIVLRCEDSSNVDAIPV
Protein: Phosphate acetyltransferase EutD (EC 2.3.1.8) (Ethanolamine utilization protein EutD) (Phosphotransacetylase EutD) (PATC EutD) (P41790)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Required for the use of ethanolamide (EA) as carbon, but not nitrogen, source (Probable). Involved in acetate metabolism during growth on EA, when expressed independently of the eut operon it can restore growth to a double pta-acs deletion mutant. Required for acetate excretion during growth on EA.
Subcellular location: Bacterial microcompartment {ECO:0000305|PubMed:23585538}.
Interaction partners:
- Acetate kinase AckA
- Acetaldehyde dehydrogenase
- Propionate kinase PduW
- Acetate kinase EutQ
- Probable acetate kinase EutP
- Corrinoid adenosyltransferase EutT
- Acetyl-coenzyme A synthetase
- Propionate kinase
- Pyruvate-flavodoxin oxidoreductase
- Malate synthase
Sequence:
MIIERARELAVRAPARVVFPDALDERVLKAAHYLQQYGLARPVLVASPFALRQFALSHRMAMDGIQVIDPHSNLSMRQRFAQRWLARAGEKTPPDAVEKLSDPLMFAAAMVSAGEADVCIAGNLSSTANVLRAGLRVIGLQPGCKTLSSIFLMLPQYAGPALGFADCSVVPQPTAAQLADIALASADTWRAITGEEPRVAMLSFSSNGSARHPNVANVQQATELVRERAPQLLVDGELQFDAAFVPEVAAQKAPDSPLQGRANVMIFPSLEAGNIGYKITQRLGGYRAVGPLIQGLAAPLHDLSRGCSVQEIIELALVAAVPRQADVSRERSLHTLVE
Protein: Os02g0691500 protein (A0A0P0VNG4)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSTLVDALCAPCSDTALIYDTFNASAAASFLFDNAAAFCDADILGATATGEKEATSSAAAAAAEAAPPRKKRRRRAKSCKSREETETQRMTHIAVERNRRRQMNEYLAILRSLMPEPYVQRGDQASIVGGAIEFVKELEQQLQSLEAQKRTLLPHHKARCDDATPMHNASGSNVGAGGCMEPTTTTSNCSSSVTEDAPSADAPPFAQFFAYPQYVWCHSPRDSTTTTTAASASASASASSSSPATVAAALQSEHRSGLADIEVSLVETHASVRVMSPRRPGQLLKMIAGLQALRLTVLHLNVTTLDSLVLYTLSVKVEEGCSLTTVDDIAAAVHHVLCIVDAEAAASEHLLAAGQLATTATAVAKRELATYMY
Protein: Kinesin-like protein KIN-12E (F4J1U4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- AT4g37660/F19F18_150
- Uncharacterized protein At3g10930
- Kinesin-like protein KIN-12F
- Kinesin-like protein KIN-14E
- Kinesin-like protein KIN-10A
- Kinesin-like protein KIN-12B
- Chaperone protein dnaJ 3
- Kinesin-like protein KIN-12A
Sequence:
MPFISETASAIKRRFGFNDRPAPSESLRSVPCTPEANTVSRDNHTHQSLLFSSAVRSMPELDEDGAICAGSAQISRSQSFEFNEDPAFWKDHNVQVIIRTRPLSSSEISVQGNNKCVRQDNGQAITWIGNPESRFTFDLVADENVSQEQMFKVAGVPMVENVVAGYNSCMFAYGQTGSGKTHTMLGDIEGGTRRHSVNCGMTPRVFEYLFSRIQKEKEVRKEEKLHFTCRCSFLEIYNEQILDLLDPSSYNLQLREDHKKGIHVENLKEIEVSSARDVIQQLMQGAANRKVAATNMNRASSRSHSVFTCIIESKWVSQGVTHHRFARLNLVDLAGSERQKSSGAEGERLKEATNINKSLSTLGLVIMNLVSVSNGKSVHVPYRDSKLTFLLQDSLGGNSKTIIIANISPSSSCSLETLSTLKFAQRAKLIKNNAIVNEDASGDVIAMRLQIQQLKKEVTRLRGMGGVDNQDMDTISMGCPASPMSLKWDGFNGSFTPLTTHKRMSKVKDYEVALVGAFRREREKDVALQALTAENEASMKLEKKREDEIRGLKMMLKLRDSAIKSLQGVTSGKIPVEAHLQKEKGDLMKEIEVLRAQVDRNQEVTKFATENLRLKEEIRRLKSQGEEGERDILNQQIQALQAKLLEALDWKLMHESDSSMVKEDGNISNMFCSNQNQESKKLSSIQDENEFLRMQAIQNRAEMESLQKSLSFSLDEKERLQKLVDNLSNELEGKIRSSGMVGDDDQMEVKTMVQAIACVSQREAEAHETAIKLSKENDDLRQKIKVLIEDNNKLIELYEQVAEENSSRAWGKIETDSSSNNADAQNSAEIALEVEKSAAEEQKKMIGNLENQLTEMHDENEKLMSLYENAMKEKDELKRLLSSPDQKKPIEANSDTEMELCNISSEKSTEDLNSAKLKLELAQEKLSISAKTIGVFSSLEENILDIIKLSKESKETEEKVKEHQSELGSIKTVSDQTNARKEVAEKKLAALRCSLSNFASSAVYFQQREERARAHVNSFSGYLNQKNEELDVIRSHKREIDAAMGKIQQSEAELKSNIVMLKIKVDEENKRHEEEGVLCTIDNILRTGKATDLLKSQEEKTKLQSEMKLSREKLASVRKEVDDMTKKSLKLEKEIKTMETEIEKSSKTRTESEMELENTIQEKQTIQEMEEQGMSEIQNMIIEIHQLVFESDLRKEEAMIIREELIAEELRAKDVHTNMIERVENALKTLENQNNSVSGKIEEEVENVLSLVHEASRLLEVSH
Protein: ETS domain-containing transcription factor ERF (Ets2 repressor factor) (PE-2) (P50548)
Organism: Homo sapiens (Human)
Function: Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Splicing factor, arginine/serine-rich 19
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 1
- Protein C-ets-2
- RNA exonuclease 1 homolog
Sequence:
MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQLSLEHRDS
Protein: Plasmodium RESA N-terminal domain-containing protein (Q8I2F2)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MAVSTYNNTRRNGLRYVLKRRTILSVFAVICMLSLNLSIFENNNNNYGFHCNKRHFKSLAEASPEEHNNLRSHSTSDPKKNEEKSLSDEINKCDMKKYTAEEINEMINSSNEFINRNDMNIIFSYVHESEREKFKKVEENIFKFIQSIVETYKIPDEYKMRKFKFAHFEMQGYALKQEKFLLEYAFLSLNGKLCERKKFKEVLEYVKREWIEFRKSMFDVWKEKLASEFREHGEMLNQKRKLKQHELDRRAQREKMLEEHSRGIFAKGYLGEVESETIKKKTEHHENVNEDNVEKPKLQQHKVQPPKVQQQKVQPPKSQQQKVQPPKSQQQKVQPPKVQQQKVQPPKVQKPKLQNQKGQKQVSPKAKGNNQAKPTKGNKLKKN
Protein: Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein) (O75027)
Organism: Homo sapiens (Human)
Function: Exports glutathione-coordinated iron-sulfur clusters such as [2Fe-2S]-(GS)4 cluster from the mitochondria to the cytosol in an ATP-dependent manner allowing the assembly of the cytosolic iron-sulfur (Fe/S) cluster-containing proteins and participates in iron homeostasis. Moreover, through a functional complex formed of ABCB7, FECH and ABCB10, also plays a role in the cellular iron homeostasis, mitochondrial function and heme biosynthesis. In cardiomyocytes, regulates cellular iron homeostasis and cellular reactive oxygen species (ROS) levels through its interaction with COX4I1 (By similarity). May also play a role in hematopoiesis (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P40416}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P40416}.
Interaction partners:
- Cytosolic Fe-S cluster assembly factor NUBP1
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
- Ferrochelatase, mitochondrial
- Mitoferrin-1
- Cytoplasmic aconitate hydratase
- Cytosolic Fe-S cluster assembly factor NUBP2
- Glutaredoxin-related protein 5, mitochondrial
- Transmembrane protein 14C
- ATP-binding cassette sub-family B member 10, mitochondrial
- Mitochondrial glycine transporter
Sequence:
MALLAMHSWRWAAAAAAFEKRRHSAILIRPLVSVSGSGPQWRPHQLGALGTARAYQIPESLKSITWQRLGKGNSGQFLDAAKALQVWPLIEKRTCWHGHAGGGLHTDPKEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQIKDKVMASPLQITPQTATVAFDNVHFEYIEGQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSRVQNHDNPKWEAKKENISKEEERKKLQEEIVNSVKGCGNCSC
Protein: Multidrug resistance outer membrane protein MdtP (P32714)
Organism: Escherichia coli (strain K12)
Function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
Subcellular location: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
- Multidrug resistance protein MdtN
- Multidrug resistance protein MdtO
- Uncharacterized protein YtcA
- Multidrug resistance protein MdtF
- Multidrug export protein EmrA
- Multidrug resistance protein MdtE
- Probable multidrug resistance protein EmrK
- Multidrug efflux pump subunit AcrA
- Multidrug export protein AcrF
- Multidrug efflux pump subunit AcrB
Sequence:
MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKLADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDAGSQLQVAALGMLNRQRVSANGFLSPYSMDAPALGMDGPYYTEATVGLFAGLDLDLWGVHRSAVAAAIGAHNAALAETAAVELSLATGVAQLYYSMQASYQMLDLLEQTHDVIDYAVKAHQSKVAHGLEAQVPFHGARAQILAVDKQIVAVKGQITETRESLRALIGAGASDMPEIRPVALPQVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAFFGLDSIHLHTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVLNAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPVLAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAGPVVEKK
Protein: Seminal fluid protein 33A1 (E1JHF8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKFFILISFLLVCQGSNEEEDNIIAELCFNPNSGPPCQKLKTYYWDKEKNRCVLSRYLMQPCGFFDTIDMCDKICTKESWTISHLEVYVRNMP
Protein: C2H2-type transcription factor RPN4 (Q6FN94)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Nucleus {ECO:0000269|PubMed:32571817}. Note=The localization to the nucleus increases upon fluconazole stress. {ECO:0000269|PubMed:32571817}.
Interaction partners:
Sequence:
MTSIDLGLKRTLTDVLEDELYNMRLREQETAQEQLDLREAGKVRQVQLQQQQMFSQYADPSVTMMSGDVACEGVLSTAPANLLANPDIRQAPAPQAQAQMLQVNPEVLISYANKNSAHMNVSAVDDKLNRGLVDENSYYDDVDYSSMNAKMADWQLDDNVAMLDNNDARLIFDNEFADDDDLSDDENLFDEGLENYHNELVSSNSPIESLDVAEHKESVDDRLRKYHLDNIQNILSKTSTNDKDILQIKLPSDFTTTNLHSTNPSGLIEDPSQLVLGSSKKITEDTHVEEESKNLPDLTELTSATEIEDILLAVDSDDDDLYTKPIAKQTTKKDNSKPVEKTVVEKTSSVTKAGSNHSRSTLARPTAHARKLSSSRKQAPKVYNPKTTTKSTHTHSKNNATHEAFVCELVNSVTNEVCGAQFSRTYDLTRHQNTIHAKKRSIFRCSECIRALGDEGFQKTFSRLDALTRHIKAKHENLSLEERQQVTKYAKSNIGFVTA
Protein: SPARC-like protein 1 (High endothelial venule protein) (Hevin) (MAST 9) (Q14515)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Myocilin
- Pleiotrophin
- Neuroligin-1
- Neurexin-1
Sequence:
MKTGLFFLCLLGTAAAIPTNARLLSDHSKPTAETVAPDNTAIPSLRAEAEENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQGKSSSQELGLKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTDSNQQESITKREENQEQPRNYSHHQLNRSSKHSQGLRDQGNQEQDPNISNGEEEEEKEPGEVGTHNDNQERKTELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKTGLEAISNHKETEEKTVSEALLMEPTDDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHLKIEEQREKVHENENIGTTEPGEHQEAKKAENSSNEEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPTCTDFEVIQFPLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDLLLRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDENLLF
Protein: Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain] (P14448)
Organism: Gallus gallus (Chicken)
Function: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots.
Subcellular location: Secreted {ECO:0000269|PubMed:10737772, ECO:0000269|PubMed:11601975}.
Interaction partners:
- Fibrinogen beta chain
- Fibrinogen C-terminal domain-containing protein.
- Uncharacterized protein
- Uncharacterized protein.
- Alpha 2-HS glycoprotein.
- Antithrombin-III
- Plasminogen
- Coagulation factor XIII B chain.
- Plasminogen
- Uncharacterized protein.
Sequence:
MIPVTILCVLLCLNLAWAQDGKTTFEKEGGGGRGPRILENMHESSCKYEKNWPICVDDDWGTKCPSCCRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQQLDENYGHVSTELRRRIVTLKQRVATQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQVDKEGYDNIQKHLTQASSIDMHPDFQTTTLSTLKMRPLKDSNVPEHFKLKPSPEMQAMSAFNNIKQMQVVLERPETDHVAEARGDSSPSHTGKLITSSHRRESPSLVDKTSSASSVHRCTRTVTKKVISGPDGPREEIVEKMVSSDGSDCSHLQGGREGSTYHFSGTGDFHKLDRLLPDLESFFTHDSVSTSSRHSIGSSTSSHVTGAGSSHLGTGGKDKFTDLGEEEEDDFGGLQPSGFAAGSASHSKTVLTSSSSSFNKGGSTFETKSLKTRETSEQLGGVQHDQSAEDTPDFKARSFRPAAMSTRRSYNGKDCDDIRQKHTSGAKSGIFKIKPEGSNKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYRRGFGSVDGKGQGELWLGNENIHLLTQNDTLLRVELEDWDGNAAYAEYIVQVGTEAEGYALTVSSYEGTAGDALVAGWLEEGSEYTSHAQMQFSTFDRDQDHWEESCAEVYGGGWWYNSCQAANLNGIYYPGGHYDPRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLETL
Protein: Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Q0KIB3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nuclear autoantigenic sperm protein homolog
- Chromatin assembly factor 1 p55 subunit
- Histone chaperone asf1
- Origin recognition complex subunit 5
- Origin recognition complex subunit 3
- Origin recognition complex subunit 4
- Origin recognition complex subunit 2
- Origin recognition complex subunit 1
- histone acetyltransferase
- AT07420p
Sequence:
MAQIEKYQDFVIDALEVVDFKLIRDKADINNDALTFHPAMAHQIFGETETIFGYQDLHVRVMYTAGPLHIYLGVDYGKRVNEISGGEIKADDVVSTIAQSLPDGCYFINLDEFLKTLDKADKFQPFGEKISEYRRVSDDGSERLFEIYQCEYKSSSFLKFFARLQTFILWFVDAASYIDTDDPQWCYFLSYEKYKNNDGQWQYATAGYTTVYEYYAYPQNKRPRISQMLILPPFQKLGLATQLVESIYRFYQSQKNVVDITVEDPSEDFQRLRNFVDARSCMKLKSFAPGEIVKGFNKEMVREAREALKLNPLQVRKVYELLRLFYTNVKDEKEYRPYRLEVKKRLNAVYYKQLKDLKKMERFKMDTEMLRARLPTVQQRMEQLHEEYRVVEQEYQSTIAKLRAS
Protein: EWS RNA binding protein 1 (B0QYK0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Protein: adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase) (Q57TY9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- 3', 5'-cyclic nucleotide phosphodiesterase, putative
- Phosphodiesterase
- Phosphodiesterase
Sequence:
MVIFMRELYVRDGVVTCVVFSLLLQVLTASSLASGEIQVKVYNMLYSGKISAKVYDPITAGFNASLTNGKSPSGGKVTVIYVPPKNDSDYVEHLEKNMSFGNNNEISVVLGPVGDKNTLNLTEYFKEKKVIGFSPFTGSSKVRSWNPNLYFLTASPAAEMLALLRYAITQLRLHRLGFMYLKNVSYGDDEYELAVELTTRMDRKLCGVFALNSQLREESDVSTFTAEWDRFADTRPQGVIVFGSPIPDTKRFLVKSLEDERTKNGYLLIPSTLQYVIDNKWSEELNRSKFPADKTIITGTNPLAKDDGYDAIKRFNREMAKFLEDNKNNFSHDKWNVTLDVNENNFTEQDTDAELMVSGWIAGEVLKQAVSCREWLTNRDVFMKSLYNQRRYVIDDLVVGDFGGECQGMAGERGASCLCNQGGNVVYMKKIGKDHRLHPMKEGALTLTSSRCYRDLSQLYAPLSGIVFNITDNPKVLRTAEAIYDGASYVVGKGQLGHSDRFFLHWLSSESHDTSTTLYDEVKERVVTAVFGVVDDSLLRTKGMTFIDPIILTPQLSDPRRNVIHLSPTLEQQLFVIAEHIIQNGTGKMHAIVRGGDAKGIGDMLNKTLDYFFGSLSSLSAIGEGSILRDKLPTAGEVLVAGLTSDDIPIILSHLGKHHKVRIFVPFFDVALLYDELVNAFRDKPFADRLLFATNLPHWRDKNTGSDMVREFHNVVQNESKWKPLSLLGYATARAMINVLQRMGHVTPEELVDAIFGQSVITVDDMRYGPFEDKCTNGVSSEEKHCAVNYGATHISVWSMSRVLNPSVSPVVNSITPSMKYNEPKWIRLINKHIGAVAAGCIVLLALFVTVLALIVKASRRNARDNNNAPKEPTDPVTLIFTDIESSTAQWAAHPEQMPDLVATHHRLIRSLITRYECYEVKTVGDSFMIACKSPFAAVQLACDLQRDFLNHDWNTTELDESYREFERQRAEDDSDYTPPTASLDPEVYRQLWNGLRVRVGIHTGLCDIRHDEVTKGYDYYGRTSNMAARTESVGNGGQVLMTRSTYLSLSGEEREQIDVTPLGDVPLRGVPKPVEMYQLNAVPGRNFAALRLDREAEEEEDNGTGSITSESGSLAHGLTATAQQVAGCIDALLGTFPAAQRQKMLATFCERWRVKKPPGVDSWNEASCRSVTRRIAAKVGCVMDFGTRNTSGSVASFERGGSLFSPGGVAAVMLASSSSSSCVAGRCGTVQLIDPESASAAS
Protein: BIV spectrin (Q9EQM0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
KPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKRLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQTAALPLEQASKELVGERQSAVGERLVRLLEPL
Protein: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha) (H0YNF5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGPAWISKVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
Protein: Glutamate dehydrogenase 2, mitochondrial (EC 1.4.1.3) (A0A140VK14)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}.
Interaction partners:
Sequence:
MYRYLAKALLPSRAGPAALGSAANHSAALLGRGRGQPAAASQPGLALAARRHYSELVADREDDPNFFKMVEGFFDRGASIVEDKLVKDLRTQESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTMELAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEVDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLSVQESLERKFGKHGGTIPIVPTAEFQDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVNAIEKVFKVYSEAGVTFT
Protein: E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Q95ZR5)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGSINTIFHRIHRFVNGTGNNARFVPSTNNSTEALTLSPRAVPSTVSDRRFLLKACKFMDQVVKSCHSPRLNLKNSPPFILDILPDTYTHLMLIFTQNNDILQDNDYLKIFLESMINKCKEIIKLFKTSAIYNDQSEERRKLTKMSLTFSHMLFEIKALFPEGIYIEDRFRMTKKEAESFWSHHFTKKNIVPWSTFFTALEKHHGSTIGKMEAAELKATIDLSGDDFISNFEFDVFTRLFYPFKTLIKNWQTLTTAHPGYCAFLTYDEVKKRLEKLTKKPGSYIFRLSCTRPGQWAIGYVAPDGKIYQTIPQNKSLIQALHEGHKEGFYIYPNGRDQDINLSKLMDVPQADRVQVTSEQYELYCEMGTTFELCKICDDNEKNIKIEPCGHLLCAKCLANWQDSDGGGNTCPFCRYEIKGTNRVIIDRFKPTPVEIEKAKNVAAAEKKLISLVPDVPPRTYVSQCSQSLLHDASNSIPSVDELPLVPPPLPPKALGTLDTLNSSQTSSSYVNIKELENVETSGEALAQVVNRQRAPSIQAPPLPPRLSASEHQPHHPYTNTNSERE
Protein: Thioredoxin (Trx) (P52231)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
Interaction partners:
- Peroxiredoxin sll1621
- Rehydrin
- Slr0600 protein
- Putative peroxiredoxin sll0755
- Chaperonin GroEL 1
- Elongation factor Tu
- Glutaredoxin arsenate reductase
- Elongation factor G 1
- Small ribosomal subunit protein uS3
- Phosphoribulokinase
Sequence:
MSATPQVSDASFKEDVLDSELPVLVDFWAPWCGPCRMVAPVVDEISQQYEGKVKVVKLNTDENPNTASQYGIRSIPTLMIFKGGQRVDMVVGAVPKTTLASTLEKYL
Protein: Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2] (P20239)
Organism: Mus musculus (Mouse)
Function: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor.
Subcellular location: [Processed zona pellucida sperm-binding protein 2]: Zona pellucida {ECO:0000269|PubMed:12799386, ECO:0000269|PubMed:17559063, ECO:0000269|PubMed:22472438, ECO:0000269|PubMed:3845123}.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:22472438}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Zona pellucida sperm-binding protein 3
- Zona pellucida sperm-binding protein 1
- Growth/differentiation factor 9
- Astacin-like metalloendopeptidase
- Oviduct-specific glycoprotein
- Acrosin
- Factor in the germline alpha
- Bone morphogenetic protein 15
- Sonic hedgehog protein
Sequence:
MARWQRKASVSSPCGRSIYRFLSLLFTLVTSVNSVSLPQSENPAFPGTLICDKDEVRIEFSSRFDMEKWNPSVVDTLGSEILNCTYALDLERFVLKFPYETCTIKVVGGYQVNIRVGDTTTDVRYKDDMYHFFCPAIQAETHEISEIVVCRRDLISFSFPQLFSRLADENQNVSEMGWIVKIGNGTRAHILPLKDAIVQGFNLLIDSQKVTLHVPANATGIVHYVQESSYLYTVQLELLFSTTGQKIVFSSHAICAPDLSVACNATHMTLTIPEFPGKLESVDFGQWSIPEDQWHANGIDKEATNGLRLNFRKSLLKTKPSEKCPFYQFYLSSLKLTFYFQGNMLSTVIDPECHCESPVSIDELCAQDGFMDFEVYSHQTKPALNLDTLLVGNSSCQPIFKVQSVGLARFHIPLNGCGTRQKFEGDKVIYENEIHALWENPPSNIVFRNSEFRMTVRCYYIRDSMLLNAHVKGHPSPEAFVKPGPLVLVLQTYPDQSYQRPYRKDEYPLVRYLRQPIYMEVKVLSRNDPNIKLVLDDCWATSSEDPASAPQWQIVMDGCEYELDNYRTTFHPAGSSAAHSGHYQRFDVKTFAFVSEARGLSSLIYFHCSALICNQVSLDSPLCSVTCPASLRSKREANKEDTMTVSLPGPILLLSDVSSSKGVDPSSSEITKDIIAKDIASKTLGAVAALVGSAVILGFICYLYKKRTIRFNH