wanglab/gogpt-training-data huggingface dataset:
Protein: Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase) (F1C7I4)
Organism: Taenia solium (Pork tapeworm)
Function: Malate dehydrogenase. Has no activity with NADPH as substrate. Does not show lactate dehydrogenase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19277715}.
Interaction partners:
Sequence:
MPGPLRVLITGAAGQIAYNLSNMVANGNLFGKDQKIILHLLDIPEAKTVLEGVVMELQDCAFTVLEGIVPTHCLKEAFTDIDVALMVGAMPRKQGMERRDLLSSNVKIFKDQGEALEKYAKKTVKVLVVGNPANTNCLIMSKYAPSIPKENFTALSRLDHNRAIYQVAAKVGVPSECVKNVCIWGNHSNKQFPDLAHAVVTKGGKQHPAKELINDEKWVKEVFTPCVQNRGAAVIGLRKLSSAASAAKAIVDQMHDWWFGTKEGEWVSMSVYSTGEHYGAPKDIYFSFPVTIKNGHYKVVDGLAMDEWGKGLFKITADELVDEREVALSSFK
Protein: Collagen triple helix repeat containing 1a (Collagen triple helix repeat-containing protein 1a precursor) (Q6AXL0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MGTKLTQLLICFWISLPFCVTQKAKERIPRQRDAEFTDKYQACVQGVPGVQGRDGNPGINGIPGTPGIPGRDGLKGEKGECVSERFEEPWKPNFKQCAWNSLNYGIDLGKIAECTFTKQRSDSALRVLFSGSLRLKCKTACCQRWYFTFNGAECTGPLPIESIVYLDQGSPELNSTINIHRTSTVEGLCEGIHAGLVDVGIWVGTCADYPRGDASTGWNSVSRVIIEELPK
Protein: Forkhead transcription factor (Eurofung) (Q5AS72)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
- Polo-like kinase
- Serine/threonine-protein phosphatase 2A activator 1
- Serine/threonine-protein phosphatase 2A activator 2
- Translation factor guf1, mitochondrial
Sequence:
MSPKQPAKRVLGAHSSQDRTTTIKPQPRLEPSPLPLQSTENPPSHHKYVLNPTSTSPNRVSPTKFSRESRTSGCAQARLGYVPITAPAPPTFTTDSPIKKIPLETYSHPTPSSAPMPQSALFTTFSSVRNVKHTTTGDLDVDVPSADTFADFPEPSQLAKHSFKRSLLDAAPLKERTKKPKGEEVTTVQLPEPHELPPIEDDGTKPPYSYATLIGMSILRAPNRRLTLAQIYRWISDTFSYYKNSDPGWQNSIRHNLSLNKAFIKQERPKDDPGKGNYWAIEPGMETQFIKDKPVRRATMTSMPTLSITPQQEPTYSQGSSATTWAVPPPAQHPVSKSSKHVDLSSDATIPASDPALQEDIGDDTAACLTTNPPRSSPPQPIHSSPPVAPPRFARPATPPTPCHPSIPSDGPRHRKRKSNTMNDSGYFSSLESSAMRSNKASHYLTSDTDIEPPRIKRGRAEEEIARIRSSSRDISPSHSGYLKETGIVVGSSPVRNEYINVLAGPLTPVIKFKKPAKPPPSVSPNTNLRNHRKKIQHMVNSPIKRLGLDEDLPWSPAFNIHDEAYTPHDGLHVSFDVFADPTTEPVSNPAYGSPEKRSAKRARTEAHGPTGNALADITALSANNRIGGLKPLSPNKSKRLFFSDSPSKLPDSGRFIDSAHDDFFSWHLFDDSPQEVDGVDLLQGFQKIGGSSKDDASKSRSHISQPTFQRGSNTRP
Protein: Klarsicht, isoform D (A8JNH2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEMQQENETGREGVIPNSEKEVALISNQETEKAAMISGGKEGSVRDLESPNETATTQKIEHTTKPLKLDGIFAMPATPPNRAGLTTKSASSSRSSSLKKQRRGSRGSANLNVAGTGDGAPKRSAPGGGQLNYGTNSVGNDLMKQSQSMTSLKASNEEQQESRDVIQAKLHLERPYNSLKKNSHSNKMHRYSWGSGNSQCSSTSLHSSATLGLGSSGKDDLWAAIQTNYNYIMDTNLLDTCKEARCEIEGAATVLEKSSECSFKMLDETQRPEGLCEDPKELRRWLREMENKLESSPTITELTLFGNAELQRHLAVHSVLYHEIASHARVVSSCIRAAEKEQQLQQQQQLSSQQPASLTSNCSSESTSESATKSSSLSSGFASDPVTTPIGTAAAAPPSSSTHPSKKGEGNLERLRDRYHLLYLKAFELQLCLDNLLRKRSSAANGLDDDEDEEEDTEDDSFGYEGEATEDDLNEVNSDLDLENSESKSATPAELILQRCQIAATQIVCGLDETQSQSRSQQVPSQAKSPSADQPRDCLAPQKPGDEADEELEEEDEDPDIGTDVVDFLIAKRSWRQVNHPNPSGTATLTDFEADSESSDFEQVQQLSRRGLPPTVGSTRRVLNLIEMPQSSNSNISSSNSLLQQRNHNIGNKMLPNKAHGKNIAVAVITPNSHGNTSHGHGLGHGLGHELNKSPLGLRKTRHHHNDTSKFNRSNRKSKNCAIFYFKHLDTDNEQGNAAGSDLQSEDDPSLIHRRRAGGDILKSADASTDDDDEGWLYTATAAATLEVATAATAAPTAAAATSSVDGLQSTAVSSTTATGGPLPPSDDSDKENKVALVSATTITAAATATATSIATLHSSNYDSSSACSSSNSNSNSNSNSNGRLTETSATSRVTQLQMQIHSQSQSQSQMELQINGNAIDGRHIISNNNCYSSMQHQPQNNNEGEAAEDLAKIKMGDDEAAADMANGNATKSQQMSNGVYSRADSCNFTVWAAETVASCHLPPRSPAKSAKSSKSQASNATVSGSTLVSPVKGKVSHDSIKQLVLEAEHLVRDAQETALKTPTKQKHSIIKISSTVKKREVTMPHPIKQRVEEWLEHQPSTPQLLTRSHTHELLPSCKPDDCEASGEASETDSVPQAGAGVNGGAPNGAGSDTSEGFTDSIATCMQTSTNSYGNSTERIGGSAEPIGQPVTPLGFGSSNQSLNVKIVKRSQTRRKSERPWSVSCLSQLTTDAAQLTTARIVENSPSGLASHSISESALDSLSPGPRPRAASSSGTGSNAAKKADSKGSLRRRKARKKRISAASAGRKSDSGSELGGDLTQTLMKSCESMSSQQLQEFTNALLSIQKGAVVAPLSPKGDVSGVPSLADGEGGETQLMLPKFRVGSFTTAGLLATDTRLGALAALSNYMNEDEQQAELSTEDHHSSISETAWDNYQEKYNSENYSEGFDSDAARRLLEFGDDYRNFIDSQSDCCSSLSAANNLDSFSPPRMDSLQKHELKTLHINQDTITSTVDHARRQRALELQYERRRKTLEVRRKSCQDMDESLMASPQSDQQQQQLQVTPSLSASATALMTTPKIQSTSHQISHRAESVGRKLDFGGMSHSAQSLLRRTSESDTSTRRRRTVTADERRRSSRNLEKCIKLIPATTSSSSGSDSEDGEQEMRSLLQQSRDRLDDTRALKIRCHLLRPEDYNEIINTCRDNIRCLEAVLRGPPGTVLSNHCAGQTKVSACLRRRRRRRLGTELPGPTESGDSRQMVHMVECQCAPITRFVARVIEFVLDVGNMLEHFALYRFLAGTLRSLYELVDRPVGGRLGRFFDGLRGLF
Protein: SNF2 DNA repair protein, putative (Q385P2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Proliferating cell nuclear antigen
Sequence:
MNCNCGTPVRCVVDKSGKICYVCQYHRCRFCANSPIQAEGWRRIVPQPPPRNGSGAVSSMETCAILRFEALLHPEKKVMYCTATPTAPMCKEVLAVLEDEQFKPMWYVKRMAYVYPIESYERLILALRKFSSHQLQVEKIPPFFFSCVQAAKDNVLEHEKQVKVNLSQGPDPDDVVYSQLHPFQKRGVGFVIARGGRGMIADDMGLGKTVQAIAFAHHYRNEWPLLIICPLSLVDNWEKEIIRFCSIPVGRIATAHTTKRFRIDGVHSIVIVPYSSLKCLEGVSVTFKVVIVDESHYIKSGTAQRTTATLKLCRAAKRVLLLSGTPAMSRPVELYSQLQAFVNPSCMPSKTQFCARYCNSFQGRFGVDCTGHSNISELHALIQHFVVRRTKSELANELPSKSRHLLYLYITPKEKAALEKDITKLRECLRNGLALPGLTDPLTPSAFASDPHGTPGGPPSQYSAGKQLNILELRTATARAKTTAVQDYIRGVAEQLVETNEKMIVFAHHRVMLDGIRDAIESVNPRKPLDYILICGNTAAAQREELLNHFRTSPTCHLAVLSMLVCGVGLNLTCATMVVFTELDWNPCTHLQCEDRVHRIGQSSSCFIKYLLAEGTSDTIIWPLLQNKLSVTKALLEDGAAANGVNGRSDGLVSKNTNVESVRRSDLSTTPPLPKGRQLTLGECKSSQTSGPSTPRTPCTERAEETPSSAAEGDGNKKTNATQLPSQGGQTAKSEEKPVFIDIPTLQKQRQERQSSLVVLQSTCSGGQPAPSVVIPVAVSPQISPSGSKPPVTTVLLGKGVVSNEPQISTAEKQVCIASSAALSPMPDLAANITPAAAITSPRTTTTTQGVTKLVESPATGPICSPSTQLRPTPPFCSPCGTVRRTPFVLSPAIAISAPSSVSQGVGGTCVSAVPSNRDVDDGVLLSNASAVSQSEALRSYNSRRTRFTVGSVGEKRVRNNNETGETQ
Protein: Epithelial cell-transforming 2 (Protein ECT2 isoform X3) (F1QVS6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Kinesin-like protein
- Rac GTPase-activating protein 1
- Si:ch1073-416j23.1.
- BUB1 mitotic checkpoint serine/threonine kinase
- Anillin
- Rho-related GTP-binding protein RhoA-B
- Condensin complex subunit 3
- Abnormal spindle-like microcephaly-associated protein
- Maternal embryonic leucine zipper kinase
- Kinesin family member 11
Sequence:
MADSSILTLGPGRSILVDSSVYDSRMAETSKEQYFIGLHSDETEGVLPRVETRVVLVGEACKMAELEKALQAITIMEVPVVKIKEGQPGTEAREKLIKSIVNMDLNTPCIKTDNVCDFGDGENCEFETVFVLKDFQAPEYSFLYKNDSRILGPPAVMHCANKGEPLPFSSRPLYSMTMLNLSLCFTGFRKKDEVVALVNLVHHMGGTIRKDFDSAKVTHLIARSTHGEKYRLAVCMGTPILTPDWIRKAWEHRDDINFHAGNELFRTEFKVPPFQDCVLSFLGFSEEEKNNMEERTQKHGGRFQAVGDERCTHLVVEENSIKELPFTPSKRLYVVKQEWFWGSIQMDARAGESMYSYEKPESPAMKKAVSLLSLTTPNSGRKRRRLRETLAQLTKETEISPFPPRKRPSAEHSLSMGSLLDISNTPDTKSSGENAKIPKSSTPALPKQSARWQVSKELYQTESNYVDILATVLQLFKYPLEKEGQVGGPILAQEEIKTIFGSIPDIYEVHTRIKADLEELVMNWSEERSVGDIILKYSGELVKAYPPFVNFFEMSKETIVRCERQKPRFHAFLKINQSKPECGRQTLVELLIRPVQRLPSVALLLNDIKKHTSDDNPDKLTLEKAIESLKEVMTHINEDKRKTEGQKQIFDVVYEVDGCPANLLSSHRSLVHRVETIALGDKPCDRGEHVTLFLFNDCLEIARKRHKVITNFRSPLGQTRPPAQLKHITLMPLSQIRRVLDIQDTEECQNAFALVVRPPTEQENLLFSFQLTAEDTLKTTWLRTLCRQVANTICRADAEDLIQSTDPDSVQVSTKDMDSTLSRASRAIKKTSKKVTRAFSFTKTPKRVLQRAFMANGTPDERSPCPDADRMSRMSSSSTLAMSRSASTFSLTGSIKSAVVQRSNSLDHAPRPRVPVCVRTPCSPERADEPAAPKSQLRPSILSLPAVQPVAKCRDLLAPPEPGRRLPGSPRRETLL
Protein: Bromodomain-containing protein 2 (Female sterile homeotic-related protein 1) (Fsrg-1) (Q7JJ13)
Organism: Mus musculus (Mouse)
Function: Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly (By similarity). May play a role in spermatogenesis or folliculogenesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:9693039, ECO:0000269|PubMed:9811568}. Chromosome {ECO:0000269|PubMed:28388437}. Note=Detected on chromatin and nucleosomes. {ECO:0000269|PubMed:28388437}.
Interaction partners:
- Histone H4
- Bromodomain-containing protein 3
- Cyclin-dependent kinase 9
- Transcription factor E2F1
- Bromodomain testis-specific protein
- Cyclin-T1
- Histone-lysine N-methyltransferase NSD3
- Histone H2A.Z
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Sequence:
MLQNVTPHKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLTKSSSESSSEESSSESSSEEEEEEEEDEDEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRIGIDEDDKGPRAPRPPQPKKSKKAGGGGSNATTLSHPGFGTSGGSSNKLPKKSQKTAPPVLPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIRKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKASEKTESSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG
Protein: Synaptobrevin homolog 1 (Q92356)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in membrane trafficking during cytokinesis and cell elongation.
Subcellular location: Membrane {ECO:0000269|PubMed:12565827}; Single-pass type IV membrane protein {ECO:0000269|PubMed:12565827}. Note=Accumulates in vesicle-like structures at the medial ring in dividing cells and at the cell ends during interphase.
Interaction partners:
- t-SNARE affecting a late Golgi compartment protein 1
- Vesicle transport v-SNARE protein vti1
- Syntaxin-like protein psy1
- Protein transport protein sec9
- Integral membrane protein sed5
- Syntaxin pep12
- Probable vesicular-fusion protein sec17 homolog
- t-SNARE affecting a late Golgi compartment protein 2
- Protein transport protein gos1
- Syntaxin-like protein fsv1
Sequence:
MSEPYDPYIPAEPSAAVRSGNAAASSTPNMKTAAIQQQIDDTVGIMRENISKVSERGERLDSLQDKTDNLAVSAQGFRRGANRVRKKMWWKDMRMRLCIIIGIIILLVVIIVPIATKFHGK
Protein: ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) (D4A7L6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- ribulose-phosphate 3-epimerase
- Transketolase
- transketolase
- transketolase
- Ribokinase
- ribose-phosphate diphosphokinase
- Phosphoglucomutase-1
- Ribose-phosphate pyrophosphokinase 2
- Ribose-phosphate pyrophosphokinase 1
- Transaldolase
Sequence:
MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNNWGLSGSHVQLPGRTQSETRGDKGGSSAGGPAPSTMSKAEEAKKLASHTAVENHVKNNQVLGIGSGSTIVHAVQRIAERVKQENLDLICIPTSFQARQLILQYGLTLSDLDQHPEIDLAIDGADEVDAELNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNLGDRWHKGIPIEVIPMAYVPVSRAVTQKFGGEVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWGEVNTAIKMTPGVVDTGLFINMAERVYFGMQDGSVNVREKPF
Protein: Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) (TPA-induced sequence 7) (TIS7 protein) (P19182)
Organism: Mus musculus (Mouse)
Function: Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.
Interaction partners:
- Ubiquitin-like protein FUBI
- Paired amphipathic helix protein Sin3b
- Histone deacetylase 1
- Interferon lambda receptor 1
Sequence:
MPKNKKRNAPHRGGGGGGGSGAATSAATAGGPHRTVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGLKNALSSKVLYEFVLERRMTLTDSIERCLKKGKSDEQRAAAAVASVLCIQLGPGFESEEILKTLGPILKKIICDGAASIQARQTCATCFGVCCFIATDDITELYSTLECFENIFTKSYLKEKDTNVTCSTPNTVLHISSLLAWTLLLTICPINEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARGMESDFFYEDMDSLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETVKFGPERMYIDSWVKKHTYDTFKEVLGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADVGEFL
Protein: Nucleosome assembly protein 1;2 (AtNAP1;2) (Nucleosome/chromatin assembly factor group A2) (Q9ZUP3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May modulate chromatin structure by regulation of nucleosome assembly/disassembly (By similarity). May function in nucleotide excision repair (NER). Involved in somatic homologous recombination.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:19228338}. Note=Predominantly located in cytoplasm.
Interaction partners:
- Histone H2A.8
- Protein NAP1
- Histone H2B.6
- ARM repeat superfamily protein
- Nodulin-related protein 1
- Transcription factor GTE2
- Zinc finger CCCH domain-containing protein 42
- Methyltransferase-like protein 2
- Smr
- SNF2 domain-containing protein / helicase domain-containing protein / HNH endonuclease domain-containing protein
Sequence:
MSNDKDSMNMSDLSTALNEEDRAGLVNALKNKLQNLAGQHSDVLENLTPPVRKRVEFLREIQNQYDEMEAKFFEERAALEAKYQKLYQPLYTKRYEIVNGVVEVEGAAEEVKSEQGEDKSAEEKGVPDFWLIALKNNEITAEEITERDEGALKYLKDIKWSRVEEPKGFKLEFFFDQNPYFKNTVLTKTYHMIDEDEPILEKALGTEIEWYPGKCLTQKILKKKPKKGSKNTKPITKTEDCESFFNFFSPPQVPDDDEDLDDDMADELQGQMEHDYDIGSTIKEKIISHAVSWFTGEAVEADDLDIEDDDDEIDEDDDEEDEEDDEDDEEEDDEDDDEEEEADQGKKSKKKSSAGHKKAGRSQLAEGQAGERPPECKQQ
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A0A2U3TZI2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGAPLNQLMRCLRKYQSRTPSPLLHSVPSEIVFDFEPGPVFRGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH
Protein: Stac-like, isoform P (A0A0B4LFF3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGISAHAAPASFWNHPRRIRRTPTSDRDGVDQCRPWICRRKDRRPAHPAANRPPESRVCGPSSTFRWDDWAAPAPRTRERATDCARMCMCTSRIPYSVARICARTTSMHSSRPASRSSSFIRRPLTRRQRMAVGGVTRRLWRTMRVYTIHQGRGVRRARAAQAVAAYLRDRRARIGKGWPAQGHGVRISATEQWADKPVVRRPGDPTRRVAAGAVPVLAERLPKVTGSSVKSSSGRRSRRRRIFGWRGPRGGSLSPQGGSMASYNGVLKDYSHSSLNEAFKSQNNVNFKLIKTVSDFSETLSRLYEEHATALQVAVSNYRKKNAELRKERPACHLAIFQAWETFLQEVETDSQACNDVASVLSRQVSRPMLDKSFHRKVQSRKIFTHRESFETIIAKTEEKLSKCRVDYKQCHLAHRQNPSQHSLTEYIDAHNAYVQQLHATNGMLEAYHTDTLPQQMQELEEIHNDLVAIVSDSLMQGAEVIAGKANDQAKRYNSLSNQCAAVSPQQDLVNFVRLLAQPSQAQKIPRRLFASPQAEVGEEAGDHNEMTPCLRNELVFDRHSTLSQRSALESLKREAIELELQIRQLQDSIEALNRTQTRGIEGQLYNKVNELQEDLSMKKFDLRAKQIHLAAIRAQKDLFVSKVEPTSPRNERKFSAATAPSMKTKWLKAFKSLKPAGSGSAQQADRRNGASSTASEPLRPNLDGSHHLQEYTYKKITACDVCSQILRGHTRQGLRCRICKLNAHGDCAPNLPRCQPKQKLLRRQKSTSELENRVDIEEEKPRYGQFFAPVSNMSSSAYISNGIGINYYTGNTQQVAYMQQVPATSSSISAGTSPAHQQQQQQQPQQCGGSTSGSSINYSTTDPGLRRRLFAGIRPLSVFGRLRQQRSSQHRSISLPETSANPKSETTRPFGEPLMLLKSTESNPDESKGNRRVR
Protein: Anaphase-promoting complex subunit 4-like WD40 domain-containing protein (O17939)
Organism: Caenorhabditis elegans
Interaction partners:
- Actin-depolymerizing factor 2, isoform c
- F-actin-capping protein subunit beta
- Actin-related protein 3
- Actin-4
Sequence:
MSEFSQTAVFPSLPRAARGVPVILGSSPAGDKILYCNGNSVFTIPIDSLNSADIYTEHAHQTTVAKISPTGFYCASGDTQGNIRIWDTTQSTHILKHTIPVFSGPVKDIAWDSESKRIAAVGEGKERFGHVFLLDTTTSNGSLTGQSRTMNSVDFKPTRPFRIISGSDDNTVAIFEGPPFKFKHTFDHHKKFVQSTRYNNDGSLFASTGSDGTVVLYNGVDGEKVGVLEDAKGVAHTGSIFALAWSPDQSRIATASADKSVKIWDVSARKLERTIVMGSKIEDQQLGIVWTKSALITVSVSGFLNFLNPDDGSVEKIRQGHNKAITALSKSSDGKFLFSADAEGHITTWEISSGTSSRKSPHTTMITGAQTSSNGDLFTVGWDDQLKITDGSGDTKSFKLPSQPCGLEVSDDLAIVACYKHVVVLSRGTPTENPIEFHSTCVAFCAEKSLVAVGGKDAKVHVYKLNGDGRLEELKKIEHSAEITAVSFSDDGEYLAVTDLARKVIPYSVSTDFSVTSPNSWTFHTSKVLTVAWSPDNQRLATGSIDTSVIIWDMKKPGEHPVIIKGAHPMSSVNVVRWLDETTVVSAGQDSNIKFWNVPL
Protein: Acyl-CoA desaturase (EC 1.14.19.1) (A0A1D8PHT9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Very-long-chain 3-oxoacyl-CoA reductase
- Elongation of fatty acids protein
- Elongation of fatty acids protein
- Acyl-CoA desaturase
- very-long-chain enoyl-CoA reductase
- Fad2p
- Very-long-chain
- Very-long-chain
- Ferroxidase
- Lanosterol 14-alpha demethylase
Sequence:
MSKHSEDPIKGVKVQKRKVASIASTSSSTSTHQQLMNQATKMKRTKINEMKKQKQDFFKRINYSHLLTVVVLPLLAVLYVVLCKQSIVPENERTLYFTCIYYNITMLAFTSGYHKYFAHNSFKVKAELLKYYFCIFGSSCGLGSVRWWAGLHRAHHHFTDDTERDPYSIKRGFLFSHYAWLLKKPKLTKFYLDFLEQEFPEHAENQKVQNEIVLDKEIETEYNGEDIMRQNYDESLRNLLMWQQRTYLFWFFVTTILIPALITKYVCGDSIVHGILYPGILRMFLCQQSLLSTESICHLKRIQVTIPTQPFNDKNSSTNCNNPLVSFLTYGQSHQNYHHEFPHDYRVDNSYLTYDPTKWFIWILEQLGAVDELSRTPGNLIVQLKLQQQQLIINRTKSQLNWGTPISKLPLISPSDFKKIISSTSNKDRIYIVIQNIIHDITPFMDQHPGGVALLKASHGKDATKAFYGGVYGHSTAAVNLLATMRIGVLDDGDDEEVWRRVAREEREVSNSTDSRPGHHHTAEAA
Protein: Delta(12) fatty acid desaturase (EC 1.14.19.6) (Delta-12 fatty acid desaturase) (Q9Y8H5)
Organism: Mortierella alpina (Oleaginous fungus) (Mortierella renispora)
Function: Catalyzes the desaturation of oleic acid (Delta(9)-18:1) to linoleic acid (Delta(9), Delta(12)-18:2).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAPPNTIDAGLTQRHISTSAAPTSAKPAFERNYQLPEFTIKEIRECIPAHCFERSGLRGLCHVAIDLTWASLLFLAATQIDKFENPLIRYLAWPAYWIMQGIVCTGIWVLAHECGHQSFSTSKTLNNTVGWILHSMLLVPYHSWRISHSKHHKATGHMTKDQVFVPKTRSQVGLPPKENAAAAVQEEDMSVHLDEEAPIVTLFWMVIQFLFGWPAYLIMNASGQDYGRWTSHFHTYSPIFEPRNFFDIIISDLGVLAALGALIYASMQLSLLTVTKYYIVPYLFVNFWLVLITFLQHTDPKLPHYREGAWNFQRGALCTVDRSFGKFLDHMFHGIVHTHVAHHLFSQMPFYHAEEATYHLKKLLGEYYVYDPSPIVVAVWRSFRECRFVEDHGDVVFFKK
Protein: Probable endoribonuclease MazF5 (EC 3.1.-.-) (Toxin MazF5) (P95272)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE5. Probably an endoribonuclease (By similarity).
Interaction partners:
- Antitoxin MazE5
- Endoribonuclease MazF9
- Probable endoribonuclease MazF1
- Endoribonuclease MazF3
- Antitoxin MazE9
- Conserved protein
- Toxin RelE
Sequence:
MTALPARGEVWWCEMAEIGRRPVVVLSRDAAIPRLRRALVAPCTTTIRGLASEVVLEPGSDPIPRRSAVNLDSVESVSVAVLVNRLGRLADIRMRAICTALEVAVDCSR
Protein: HOXB1 protein (Q4VB01)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDYNRMNSFLEYPLCNRGPSAYSAHSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGHSEGDGGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTGRAQMWPPLLRGPKHLCFPCSDMSWVWAGFFSFSGSGRHR
Protein: ER-phagy receptor 1 (Meiotically up-regulated gene 185 protein) (O14213)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Reticulophagy receptor required for autophagosomal sequestration of endoplasmic reticulum (ER) membranes during ER stress (Ref.5). Confers resistance to ER stress by promoting the autophagic degradation of the ER (ER-phagy or reticulophagy) (Ref.5). Acts as a bridging molecule to mediate the association between atg8 on the autophagic membrane and the vesicle-associated membrane protein-associated proteins (VAPs) scs2 and scs22 on the ER (Ref.5). May play a role in meiosis.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16823372, ECO:0000269|Ref.5}. Preautophagosomal structure {ECO:0000269|Ref.5}. Note=Accumulates at the preautophagosomal structure when autophagy occurs. {ECO:0000269|Ref.5}.
Interaction partners:
- Mitophagy receptor atg43
- Cytoplasmic 60S subunit biogenesis factor SPCC550.15c
Sequence:
MNNPFKDMDCYEILQVNHDSDLQEIKANYRKLALQYHPDRNPGIEDYNEIFSQINAAYNILSNDDKRKWHEKDYLRNQYSVQIEDVLQHLQTIEKIPFESTSAFVERLRQDEKIAGSTDDLPTLGDTTWLWTYAKPIYQKWLRFSTKKSFEWEALYNEEEESDAATRRLMKRQNQRQIQYCIQRYNELVRDLIGKACDLDPRRKNVVKLSDGERYNSLQEASRKQSERDRRQYQETFKNQSIASWTIIDQEETSSDDESLSKEIVNSNPIMCMVCNKNFRSQNQLENHENSKKHKKNLRKMNQEIKKHAKEAQKNAESNKQPEDAPSESPYSNKVSSSDFYTRSFEEIEKTFTFVEISDNEFYTASEDGFLNEDDKLDQD
Protein: Uncharacterized protein (A0A1D8PN67)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MDGHDWFLVFVGFFLPPVPVLIKRGFFSADFWINILLCLLGFLPGLLHSYYIISVYPYRATYAALGGDGHNNRSDDYGATTST
Protein: Monocarboxylate transporter 1 (Solute carrier family 16 member 1) (Q5T8R5)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004424}. Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}.
Interaction partners:
Sequence:
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANE
Protein: Cytochrome P450 26C1 (CYP26C1) (EC 1.14.14.1) (Q6V0L0)
Organism: Homo sapiens (Human)
Function: Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Retinal dehydrogenase 2
- Retinaldehyde dehydrogenase 3
- Aldehyde dehydrogenase 1A1
- Cytochrome P450 4A11
- Cytochrome P450 4A22
- Cytochrome P450 3A7
- Cytochrome P450 3A4)
- Cytochrome P450 3A5
- Cytochrome P450 26A1
- Cytochrome P450 2S1
Sequence:
MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL
Protein: Single-stranded DNA-binding protein, mitochondrial (Dm mtSSB) (Mt-SSB) (MtSSB) (Protein low power) (P54622)
Organism: Drosophila melanogaster (Fruit fly)
Function: Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA). Required to maintain the copy number of mitochondrial DNA (mtDNA) and plays crucial roles during mtDNA replication that stimulate activity of the gamma complex polymerase PolG1/tam at the replication fork. Promotes PolG1 activity largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate PolG1 activity.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:7673145}.
Interaction partners:
- Mitochondrial DNA helicase
- DNA polymerase subunit gamma-1, mitochondrial
- DNA-directed RNA polymerase
- Small ribosomal subunit protein bS6m
- Mitochondrial transcription factor A, isoform B
- Ribonuclease H1
- DNA topoisomerase 3-alpha
- Large ribosomal subunit protein bL21m
- DNA polymerase subunit gamma-2, mitochondrial
- Small ribosomal subunit protein uS10
Sequence:
MQHTRRMLNPLLTGLRNLPARGATTTTAAAPAKVEKTVNTVTILGRVGADPQLRGSQEHPVVTFSVATHTNYKYENGDWAQRTDWHRVVVFKPNLRDTVLEYLKKGQRTMVQGKITYGEITDQQGNQKTSTSIIADDVLFFRDANN
Protein: V-type proton ATPase subunit H (Q6PC35)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISGEDCEFIKKFEVAGSEDKQAILTNEGHQCAKTFLNLMAHISKEQTVQYILTLIDDTLQENHQRVNIFFDYAKKTKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGRDLMEGSDLNYYFNWIKTQLSSQSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCITAVLSNKCGFQLQYQMIFCVWLLAFSPQLCEQLRRYNVVPALSDILQESVKEKVTRIILAAFRNLLEKSAERETRQEYALAMIQCKVLKQLENLDQQKYDDEDITDDIKFLLERLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTRLLEVSDDPQVIAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQLVRYNALLAVQKLMVHNWEYLGKQLQSTEQTTPAVAARS