wanglab/gogpt-training-data huggingface dataset:
Protein: Protein FERTILITY RESTORER RF2, mitochondrial (F1SZ41)
Organism: Oryza sativa subsp. indica (Rice)
Function: Restores fertility in rice varieties with LD-type cytoplasmic male sterility (CMS). CMS is caused by genetic incompatibility between nuclei and mitochondria within male reproductive organs. Corresponds to the functional allele of RF2, which is dependent of the presence of Ile-78 in the japonica cultivars Fukuyama and Owarihatamochi (AC F1SZ42), and indica cultivar Kasalath (AC F1SZ41). Non-functional RF2 alleles are found in japonica cultivars Taichung 65 and Nipponbare (AC F1SZ44), where Ile-78 is replaced by Thr-78.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:21265890}.
Interaction partners:
Sequence:
MSTLVTCSLPGAVTTHASTRRFGGSQFQTSQASCISFKREVSAKAVLRSVRCNATQTQSAQRKSSTATVKRSDPKGKIQGPKLDDGSGGFPPFRFGKGGGGGGGGGGGSNYFGGFLLFTCVLLLDYLKEFEKNLIARRQRAGYDANNDMFQQ
Protein: Soluble inorganic pyrophosphatase 6, chloroplastic (EC 3.6.1.1) (Inorganic pyrophosphatase 6) (Pyrophosphate phospho-hydrolase 6) (PPase 6) (Q9LXC9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:15135060}.
Interaction partners:
- ATP synthase subunit b, chloroplastic
- Putative ATPase, plasma membrane-like
- Serine/threonine-protein kinase ATR
- ATP synthase subunit delta, chloroplastic
- Adenylyl-sulfate kinase 3
- ATPase 4, plasma membrane-type
- ATPase 7, plasma membrane-type
- ATPase 6, plasma membrane-type
- ATPase 8, plasma membrane-type
- ATPase 9, plasma membrane-type
Sequence:
MAATRVLTAATAVTQTTSCFLAKQAFTLPAKKSCGGFGGLCFSRRALVLKSKRPFSCSAIYNPQVKVQEEGPAESLDYRVFFLDGSGKKVSPWHDIPLTLGDGVFNFIVEIPKESKAKMEVATDEDFTPIKQDTKKGKLRYYPYNINWNYGLLPQTWEDPSHANSEVEGCFGDNDPVDVVEIGETQRKIGDILKIKPLAALAMIDEGELDWKIVAISLDDPKAHLVNDVEDVEKHFPGTLTAIRDWFRDYKIPDGKPANRFGLGDKPANKDYALKIIQETNESWAKLVKRSVDAGDLSLY
Protein: Ubiquitin-conjugating enzyme E2 Q1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q1) (Protein NICE-5) (Ubiquitin carrier protein Q1) (Ubiquitin-protein ligase Q1) (Q7Z7E8)
Organism: Homo sapiens (Human)
Function: Catalyzes the covalent attachment of ubiquitin to other proteins. May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q7TSS2}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q7TSS2}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q7TSS2}.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 Q2
- Ubiquitin-conjugating enzyme E2Q-like protein 1
- Ubiquitin-conjugating enzyme E2 Z
- Ubiquitin-conjugating enzyme E2 R2
Sequence:
MQQPQPQGQQQPGPGQQLGGQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG
Protein: ARF GAP-like zinc finger-containing protein ZIGA4 (F4HXP0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MMGSKREEERNEKIIRGLMKLPPNRRCINCNSLGPQYVCTTFWTFVCMACSGIHREFTHRVKSVSMSKFTSKEVEVLQNGGNQRAREIYLKNWDHQRQRLPENSNAERVREFIKNVYVQKKYAGANDADKPSKDSQDHVSSEDMTRRANSYHSYSQSPPYDYQYEERRYGKIPLGFTGKSASVKGLHAKASSFVYSPGRFSDHMFEDQFSNEDSAPRASDYSVSSAGDPFRSDIQSPNFQQEAEFRSPQFQHSNAPPSENLFPGRQHQRTTSSGSVRSVDSNFMSIKSYTSGGLGEAVSESRQNTGSQQGKTSNHVPLVAESTKAPIDLFQLPGAPVAQSVDTFQPSIAPRSPPVNLQQAPQTYSFTPANSFAGNLGQQPTSRPSELSAPKNEGWASFDNPMPAAKSTNVITSPGDFQLELKIEEILQPSTSMQLPPYPSTVDQHALSIPSPWQEDLSNVLKDVVDNPQPWNAFPDSIEANPLDSSRNIHQQVDGASTSSYNTDHQHLESQVLESQELSNDGTQTTRIPAGSSAFGFPGNIGMAPSYSEEAWQHVNEQKSANPFDLPYDSEFDSNDMFLDMSSLQGALPDIQTPQAFLNGVSQPWLAADSVPSYLPAPAVAQGGLAYMAGQASTNSAAQGPVAFTGGNPFA
Protein: Thrombospondin, isoform A (Thrombospondin, isoform F) (Q9VM97)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- AT06841p1
- Integrin beta-PS
- Integrin beta-nu
- RE20510p
- GH19763p)
Sequence:
MNWTRVLLIGLTALALTFVDVASLSLDPVASAELEQFIRKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKHKMSFFLDRKQQRVTLDISANGATESRNFEIPNINETSTIRSLALQFSKNRITLHVDCKASTHHDIDMNLAKLYTQMDDPVIKLFRERKYPLHFDGDMEHSLQRANCQKGNHRRGNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHRHQEVPTDVERGDIPVLNGDCEDALARSLSDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVECLDSAAGPRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSGAQCLQVGYPPYFHCISCPMGHEVNGTSCRDMNECLLYDPCDELATCTNLSPGFQCSPCPVGFDGTHAHGYFADYYSVDYRRQTCLDVDECRTGFFRCPEHSTCINEIGSYRCQCHEGYVTNGTYSCLDRSSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAGNGLICGRDTDVDGWPDQAIGCPELRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDGDKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPNYKDNCPLAKNPKQDDFNRNGKGDSCEDDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVKPLIYNDLSDYLKTKVELQD
Protein: Apelin (APJ endogenous ligand) (Q4TTN8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Endogenous ligand for the apelin receptor (aplnra and/or aplnrb). Drives internalization of the apelin receptor (By similarity). Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis. Plays a role in early coronary blood vessels formation. Mediates myocardial contractility in an ERK1/2-dependent manner. May also have a role in the central control of body fluid homeostasis (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q9TUI9}. Secreted, extracellular space {ECO:0000250|UniProtKB:Q9TUI9}.
Interaction partners:
- Apelin receptor A
- Apelin receptor B
- Apelin receptor 2
- Apelin receptor early endogenous ligand
- Pro-opiomelanocortin protein
- Type-1 angiotensin II receptor
- Peptide YY-A
- Arrestin, beta 2a.
- Neuropeptide B
- Beta-arrestin-1
Sequence:
MNVKILTLVIVLVVSLLCSASAGPMASTEHSKEIEEVGSMRTPLRQNPARAGRSQRPAGWRRRRPRPRLSHKGPMPF
Protein: Carnitine O-Acetyl-Transferase, isoform B (EC 2.3.-.-, EC 2.3.1.7) (Q0KIA8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MYKYQSPTSERILEKTEAEMKFRGNGKLLWNLTKNSLAQQSPNGIAKKVLPASSYSTVQKTIPLEQPNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLLEETGSKEKNWLAHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTARVIYGLGEFNDMVHANKIPIVKMGKNELDNSQFGKVFGTCRIPRRGTDEIVYNPDSDYVVVIYKNHFYQLKIYSKEGKLIAAPCLAAQLENIVLKETQVGVPYGILTTDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDEGTILKEGEETDELILSLIHGSGSKINSGNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIAMMMDYVVQKMKEDPSFGQSGSQDFAPAQKIQFSSSNKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATKYDAFMGYGPATDDGYACCYNPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEMKNVLEKNPPETKSKL
Protein: Small GTPase, putative (Q38A82)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
- Ras-family member, GTP-binding protein, putative
- Vacuolar membrane-associated protein Iml1 N-terminal domain-containing protein
- WD repeat protein mio zinc-ribbon like domain-containing protein
- Raptor N-terminal CASPase-like domain-containing protein
- Raptor N-terminal CASPase-like domain-containing protein
- Uncharacterized protein
- WD repeat protein mio zinc-ribbon like domain-containing protein
- WD repeat protein mio zinc-ribbon like domain-containing protein
- non-specific serine/threonine protein kinase
- Serine/threonine-protein kinase TOR
Sequence:
MTSSFLAHPKVLLMGLRKSGKTSIQKVVFEGMQPHHCVDLTTTVQPEKSTVCSYDFVNFEVWDFPGQTDPFDLNNTVHYDVGVLLENCGAIVFVMDCGELIDDSHARLVETVCAAYDRDPELSVEVFIHKVDKLSEDHQADLLTSLQRRVEAEARQRLNATAQLRLNFNLTSIYDHSVFQAFSSVVQKLMKLQIPYITELLQILNSNSNLDLSYLFLSRSKIFLSVDERNRVKTRTYEICSDAIEVMMGMNRIYSKGKEQGEGDEEEVSSGARGTEAEVYAGANIVIKLSSDDCIYVKELPNSLTLVSMVKNESFRNRILIDHNISAFYNAAYSIFRRN
Protein: Ran-binding protein 6 (RanBP6) (O60518)
Organism: Homo sapiens (Human)
Function: May function in nuclear protein import as nuclear transport receptor.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- GTP-binding nuclear protein Ran
- THO complex subunit 4
- Importin subunit beta-1
- Transportin-1
- Importin-4
- Sentrin-specific protease 2
- Sentrin-specific protease 1
Sequence:
MAATASAGVPATVSEKQEFYQLLKNLINPSCMVRRQAEEIYENIPGLCKTTFLLDAVRNRRAGYEVRQMAAALLRRLLSSGFEEVYPNLPADVQRDVKIELILAVKLETHASMRKKLCDIFAVLARNLIDEDGTNHWPEGLKFLIDSIYSKNVVLWEVALHVFWHFPGIFGTQERHDLDIIKRLLDQCIQDQEHPAIRTLSARAAAAFVLANENNIALFKDFADLLPGILQAVNDSCYQDDDSVLESLVEIADTVPKYLGPYLEDTLQLSLKLCGDSRLSNLQRQLALEVIVTLSETATPMLKKHTNIIAQAVPHILAMMVDLQDDEDWVNADEMEEDDFDSNAVAAESALDRLACGLGGKVVLPMTKEHIMQMLQSPDWKYRHAGLMALSAIGEGCHQQMESILDETVNSVLLFLQDPHPRVRAAACTTLGQMATDFAPNFQKKFHETVIAALLRTMENQGNQRVQSHAASALIIFIEDCPKSLLVLYVDSMVKNLHSVLVIKLQELIRNGTKLALEQLVTTIASVADTIEEKFVPYYDIFMPSLKHIVELAVQKELKLLRGKTIECISHIGLAVGKEKFMQDASNVMQLLLKTQSDLNNMEDDDPQTSYMVSAWARMCKILGKDFQQYLPLVIEPLIKTASAKPDVALLDTQDVENMSDDDGWQFVNLGDQQSFGIKTSGLEAKATACQMLVYYAKELREGFVEYTEQVVKLMVPLLKFYFHDNVRVAAAESMPFLLECARIRGPEYLAQMWQFICDPLIKAIGTEPDTDVLSEIMNSFAKSIEVMGDGCLNDEHLEELGGILKAKLEGHFKNQELRQVKRQEENYDQQVEMSLQDEDECDVYILTKVSDILHSLFSTYKEKILPWFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPTSFKYVEYFRWPMLLNMRDNNPEVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKTKKNVIATENCISAIGKILKFKPNCVNVDEVLPHWLSWLPLHEDKEEAIQTLSFLCDLIESNHPVVIGPNNSNLPKIISIIAEGKINETINYEDPCAKRLANVVRQVQTSEDLWLECVSQLDDEQQEALQELLNFA
Protein: Battenin (O95085)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}. Lysosome membrane {ECO:0000256|RuleBase:RU361113}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361113}.
Interaction partners:
Sequence:
MCRLAAALFGFRGLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGSSSSLSLRERWTVFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQMLYQAGVFASRSSLRCCRIRFTWALA
Protein: tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6) (Q5XFW6)
Organism: Rattus norvegicus (Rat)
Function: Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9NNW5}. Note=Colocalizes in the cytoplasm with STK11/LKB1. {ECO:0000250|UniProtKB:Q9NNW5}.
Interaction partners:
- Putative tRNA
- rRNA methyltransferase 2, mitochondrial
- U3 small nucleolar RNA-associated protein 15 homolog
- pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3
- Nucleolar protein 56
- GPALPP motifs-containing protein 1
- Armadillo repeat-containing protein 6
- DALR anticodon-binding domain-containing protein 3
- Transducin
- 15-oxoprostaglandin 13-reductase
Sequence:
MDAFGDYVWPRATSELILLPVTGLECVGDRLLAGEGPDLLVYNLDFGGHLRMVKRVQNLLGHYLIHGFRVQPEPKGDLDSEAMIAVFGSKGLRVVKISWGQSHLRELWRSGLWNMSDWIWDARWLEGNVALALGHNSVVLYDPVIGCMLQDVPCTDRCTLSSACLIGDTWKELTIVAGAVSNELLVWYPATALPDNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLISAGEDCVCLVWSHEGEILQAFRGHQGRGIRAIAAHERQTWVITGGDDSGIRLWHLVGRGYPGLGVSSLSFKSPSRPGALKAVTLAGSWRVLAVTDVGGLYLYDLEVKCWEQLLEDNRFQSYCLLEAAPGPEGFGLCALANGEGLVKVVPINTPTAAVDQNLFQGKVHSLSWALRGYEELLLLASGPGGVVACLEISAAPTGKAIFVKERCRYLLPPSKQRWHTCSAFLPPGDFLVCGDRRGSVLLFPARPCLFKKPGVGPKAITAAEAPQAGSSSGGSESVVTGLGPVSSLHSLHGKQGVTSVTCHGGYVYSTGRDGSYYQLFVHGGRLQPVLRQKACRGMNWIAGLRMAPDGSMVVLGFHANEFVVWSPRSHEKLHIVNCGGGHRSWAFSDTEAAMAFAYLKDGDVMLYRALGGCIRPNVILREGLHGREITCVKRVGTVTLGPEFEVPNLEHPDSLEPGSEGPGLIDIVITGSEDTTVCVLALPTTTGAAHALTAVCNHISSVRALAVWGVGTPGGPQDSHPGLTAQVVSAGGRAEMHCFSLMITPDASTPSRLACHIMHLSSHRLDEYWDRQRNRHRMIKVDPETRYMSLAICELDSDRPGLGPGPLVAAACSDGAVRLFLLQDSGRILHLLAETFHHKRCVLKVHSFTHEAPNQRRRLILCSAATDGSIAFWDLTTAMDRGSTTLEPPAHPGLPYQMGTPCLTVQAHSCGVNSLHTLPTPEGHHLVASGSEDGSLHVFTLAVKMPELEEADGEAELVPQLCVLDEYSVPCAHAAHVTGIKILSPKLMVSASIDQRLTFWRLGNGEPTFMNSTVYHVPDVADMDCWPVNPEFGHRCALAGQGLEVYNWYD
Protein: C2 calcium-dependent domain-containing protein 4A (Nuclear-localized factor 1) (Protein FAM148A) (Q8NCU7)
Organism: Homo sapiens (Human)
Function: May be involved in inflammatory process. May regulate cell architecture and adhesion.
Subcellular location: Nucleus {ECO:0000269|PubMed:15527968}.
Interaction partners:
- Rho-related GTP-binding protein Rho6
- Sodium leak channel NALCN
- Protein unc-79 homolog
Sequence:
MWCLERLRLGPECLRRSGDWLLPGRARGAKSRTTAACANVLTPDRIPEFCIPPRLMPRLALAALRNSWVEEAGMDEGAGRTDWDPRSQAALSLPHLPRVRTAYGFCALLESPHTRRKESLLLGGPPAPRPRAHTYGGGGGPDALLGTLRVPRAPGPATPAAPGCPRPPQDALARRPRGCRLLRVPDGLLSRALRAGRSRRLTRVRSVSSGNEDKERRAGSQSPARAPSTSPPSSRVPFPERLEAEGTVALGRAGDALRLAAEYCPGTGRLRLRLLRAESPAGGAPGPRAVSCRLSLVLRPPGTALRQCSTVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRERGRLLGQGELSLGALLLL
Protein: 12S seed storage protein CRA1 (Cruciferin 1) (AtCRU1) (Cruciferin A1) (Legumin-type globulin storage protein CRA1) [Cleaved into: 12S seed storage protein CRA1 alpha chain (12S seed storage protein CRA1 acidic chain); 12S seed storage protein CRA1 beta chain (12S seed storage protein CRA1 basic chain)] (P15455)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Seed storage protein.
Subcellular location: Protein storage vacuole {ECO:0000305}.
Interaction partners:
- 2S seed storage protein 2
- 2S seed storage protein 1
- 2S seed storage protein 3
- NADPH-dependent aldehyde reductase 1, chloroplastic
- 2S seed storage protein 5
- Nucleolin
- Late embryogenesis abundant protein 29
- 1-Cys peroxiredoxin PER1
- Oleosin 21.2 kDa
- DNA repair protein XRCC3 homolog
Sequence:
MARVSSLLSFCLTLLILFHGYAAQQGQQGQQFPNECQLDQLNALEPSHVLKSEAGRIEVWDHHAPQLRCSGVSFARYIIESKGLYLPSFFNTAKLSFVAKGRGLMGKVIPGCAETFQDSSEFQPRFEGQGQSQRFRDMHQKVEHIRSGDTIATTPGVAQWFYNDGQEPLVIVSVFDLASHQNQLDRNPRPFYLAGNNPQGQVWLQGREQQPQKNIFNGFGPEVIAQALKIDLQTAQQLQNQDDNRGNIVRVQGPFGVIRPPLRGQRPQEEEEEEGRHGRHGNGLEETICSARCTDNLDDPSRADVYKPQLGYISTLNSYDLPILRFIRLSALRGSIRQNAMVLPQWNANANAILYVTDGEAQIQIVNDNGNRVFDGQVSQGQLIAVPQGFSVVKRATSNRFQWVEFKTNANAQINTLAGRTSVLRGLPLEVITNGFQISPEEARRVKFNTLETTLTHSSGPASYGRPRVAAA
Protein: Glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) (Peptide N-myristoyltransferase) (dNMT) (O61613)
Organism: Drosophila melanogaster (Fruit fly)
Function: Adds a myristoyl group (tetradecanoyl group) to the N-terminal glycine residue of certain cellular proteins (Probable). Such protein modification are critical for the developmental processes that involve cell shape changes and movement.
Subcellular location: Membrane {ECO:0000269|PubMed:9044045}; Peripheral membrane protein {ECO:0000269|PubMed:9044045}.
Interaction partners:
- Methionine aminopeptidase
- G protein alpha i subunit subunit alpha 65A)
- Methionine aminopeptidase
- Methionine aminopeptidase 2
- Acyl-CoA-binding domain-containing protein 6
Sequence:
MPNENAEDLSGQELKQKAKEVADASEAMLEKVVAGLNIQDTASTNAAGNEDAEQPDGAKNEASVSANASKQALLQAVSDAMASTRQMAKKFAFWSTQPVTKLDEQVTTNECIEPNKEISEIRALPYTLPGGFKWVTLDLNDANDLKELYTLLNENYVEDDDAMFRFDYQPEFLKWSLQPPGWKRDWHVGVRVEKSGKLVGFISAIPSKLKSYDKVLKVVDINFLCVHKKLRSKRVAPVLIREITRRVNLTGIFQAAYTAGVVLPTPVATCRYWHRSLNPKKLVDVRFSHLARNMTMQRTMKLYKLPDQPKTKGYRRITAKDMDKAHKLLEDYLKRFQLSPVFSKEEFRHWFTPKEGIIDCFVVADEKGNITDLTSYYCLPSSVMHHPVHKTVRAAYSFYNVSTKTPWLDLMNDALISARNVQMDVYNALDLMENKKYFAPLKFGAGDGNLQYYLYNWRCPSMQPEEIALILM
Protein: Notch 3 protein (Q14962)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
GGRSQVGAQFLPDYPPPHSTDSKCFPSRRWWIGAAASLVKTGVAASRLGPIAFFPLDGADASXTSEACPAGRPQPRSVSGSMWAGVWGLWKGLMHVPPASXSRMGG
Protein: Tail-specific protease (EC 3.4.21.102) (C-terminal-processing peptidase) (PRC protein) (Protease Re) (P23865)
Organism: Escherichia coli (strain K12)
Function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses.
Subcellular location: Cell inner membrane; Peripheral membrane protein; Periplasmic side.
Interaction partners:
- Lipoprotein NlpI
- RNA chaperone ProQ
- Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase
- Periplasmic serine endoprotease DegP
Sequence:
MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
Protein: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) (EC 1.17.7.1) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) (Q8DK70)
Organism: Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)
Function: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate, using ferredoxin I (PetF) as the reducing agent.
Interaction partners:
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
- 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
- 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
- 1-deoxy-D-xylulose-5-phosphate synthase
- 1-deoxy-D-xylulose 5-phosphate reductoisomerase
- 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
- Dihydroxy-acid dehydratase
- cysteine desulfurase
- Tll0464 protein
- Quinolinate synthase
Sequence:
MQTLPSPVQATPTETAIVRRKTRPVPIGSVVIGGGHPVAVQSMINEDTLDIEGSVAAIRRLHEIGCEIVRVTVPSLAHAKAMEEIRDRLYKTYKPVPLVADVHHNGMKIALEVAKYVDNVRINPGLYVFEKPKPNRTEYTQAEFDEIGAKIRETLEPLVISLRDQGKSMRIGVNHGSLAERMLFTYGDTPEGMVESALEFIRICESLNFYNLEISLKASRVPVMIAANRLMVKRMDELGMDYPLHLGVTEAGDGEYGRIKSTAGIATLLAEGIGDTIRVSLTEAPEKEIPVCYGILQALGLRRTMVEYVACPSCGRTLFNLEEVLHKVREATKHLTGLNIAVMGCIVNGPGEMADADYGYVGKQPGYISLYRGREEVKKVPEAEGVAALVELIKADGRWVDP
Protein: Oxidoreductase, short-chain dehydrogenase/reductase family (O06172)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVTVDVRPADLADPQERSKLADELAARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATKAFVNTFSESLRGELRGSGVHVTVLAPGPVRTELPDASEASLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSKAMSVASQYAPRAIVAPIVGAFYKRLGGS
Protein: Glycosidase (EC 3.2.-.-) (G8BI19)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Cell envelope {ECO:0000256|ARBA:ARBA00004196}. Membrane {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004589}.
Interaction partners:
Sequence:
MLISRAFSLASILITTVSAATSTASCNPIKSSSCSPNPALGGSMQENFQNGLGSYFTNSGNQGDVKTGDEGLSLTVNKRFDNPSIHSDFYLMFGYVEVELKAGEGKGIVSSFFLQSDDLDEIDIELFGGDEYEWQSNYFVQGNTSTYDRGGYHSINPSPLTNYHKYAINWTKDSLDWIVDGSVIRSLHITNSQGYPQSPMRIYAGIWAGGDPSNEEGTILWAGGETDYSQAPFTMHIKSITAIDYSTGSEYSYSDQSGYWQSIDAKDGEVNGRYSDAQSDVNKAVNGDSIENSGSSDSPSTTQSSSESSSTTESSSESSSTTESSSESSSTTESSSESSSTTESSSESSSTTESSSESSSTTESSSESSSTTENSSSFSESTQESQSSSEPNSSASSAETTETSESTQTTRGGANKVETDASSFSSSVATTSAETDSSEQETTTSSSSSSDETHSVSSSSENSACRFTSPRSMQFVTVLVSFVSFGFVLV
Protein: ferroxidase (EC 1.16.3.1) (Q7ZU12)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MKGLQFALLWVLCCAGIASSITREYFFAIKEIQWDYAPSGKNLIQNKTVQQDEAARVFLERGEQRIGRVYKKAVYHQYTDATYRQEIDKPKWLGYLGPLISAEEDDTVIVHLKNMARRAYSLHAHGLSYNKTNEGALYPDSSEKVEKHDDSVAPGTTFTYIWTLPASHAPGKDDTNCLTRIYHSHVNAPKDIASGLIGPLIVCKKGSLDVHGDKTGDYLYTLMFTVSDENLSWYLDENIKTYCSAPAKVNKDDEAFQESNKMHSINGYVYGNLPDLSMCMGNKIHWHLFGMGNEVDIHSAFFHGQILTDKRQHVDTVSLFPATFVNVEMVADNPGQWLLSCQVNDHLEAGMQAFFEIKKCFPNVHKPRPFGEVRQYYIAAEEIIWDYGPTEINQYTMKKLVDDIVSDTFFDNRNDRIGGKYKKVQYVEYTDDTFTKRKEKTPEEQHLGILGPVIRAEEEDTIKVTFRNKASRPFSIQPHGVQYNIDMDGTLYHNVLEESYTDKKLRELKKQPRVIEPLPAAMVRPDTTYKYEWVVPKDGGPTEKDPDCLTYLYYSAVDPIRDTNSGLVGPLLICKPKTLKSGKQKNVDKEFHLLATVFDENLSWYLDDNINRYAKQPKSVNKEDADFQESNKMHSLNGYMYGNLKGLNMCKGDKVSWHLSGLGSETDIHGLYFEGNRFLYKETRRDTINVFPHISHTVIMEPDSMGQFEVNCKTTDHYHGGMRANYTVEKCRFWNRQSETMLHQKKYYIAAVEMDWDYSPTRTWEDKMHNGLKESPGNEFLKKEGKFIGSKYKKVLYKEYTDETFTKLKERTADMEHLGIMGPMIHGKVGEKVKIVFKNMARRPYSIHAHGVKTDSPQVPLTRPGETQTYTWYLPKNSGPTEEQEECSVGAYYSTVDVIKDMYSGLVGPLVICKKSLARTLGLKKEVEEFALLFMVFDENESWYLEENIKTHVKNPPKALTEDQQFIESNKMHGINGLVFGNLKGLNMKVGDKVYWYLMGLGNEVDIHTAHFHGHSFDYKVSGTHRADVFDLVPGTFQTVTMRPLYSGTWLLHCHVTDHIQAGMETTYTVLEKDGRKRGFLGIFGSG
Protein: Heterogeneous nuclear ribonucleoprotein H (hnRNP H) (Ratsg1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed] (Q8VHV7)
Organism: Rattus norvegicus (Rat)
Function: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:19343716}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein A1
- Serine/arginine-rich splicing factor 2
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoprotein A3
- Heterogeneous nuclear ribonucleoprotein C
- Heterogeneous nuclear ribonucleoprotein Q
- Serine/arginine-rich splicing factor 1
Sequence:
MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSEEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIETGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA
Protein: Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (3-OST-2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2) (Q9Y278)
Organism: Homo sapiens (Human)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS. Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Sulfotransferase 1C3
- Sulfotransferase 1C4
- Sulfotransferase 1B1
Sequence:
MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE