wanglab/gogpt-training-data huggingface dataset:
Protein: Transcription factor GTE10 (Bromodomain-containing protein GTE10) (Nuclear protein X1) (Protein GLOBAL TRANSCRIPTION FACTOR GROUP E10) (Q9FGW9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a negative regulator in plant response to changes in environmental conditions through the control of ABA-regulated gene expression.
Subcellular location: Nucleus {ECO:0000269|PubMed:19759343}.
Interaction partners:
- SWR1-complex protein 4
- Putative DNA glycosylase At3g47830
- Probable WRKY transcription factor 57
- Methyl-CpG-binding domain-containing protein 9
- Autophagy-related protein 9
- Histone deacetylase 9
- Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1
- Ninja-family protein AFP4
Sequence:
MGKARKHSRGRPSGFVPDYMQAVEPDEFVYSERMNSEASPPLKRRRFGLNGDNNGVSKEVLSLSKMSRSERKNLVHKLKMELQQVRDLSKKIASFSSDTVLLSPYNDHSCSDGPRRPPPENFATFVGSQGKKRPPVRSDKQRNKKGPSRLNVPTSYTVASVMKECETLLNRLWSHKSGWPFRTPVDPVMLNIPDYFNVIKHPMDLGTIRSRLCKGEYSSPLDFAADVRLTFSNSIAYNPPGNQFHTMAQGISKYFESGWKSIEKKIPMSKPPVIPLTSSASLESEIPFEVAPMRKKEAAMNDNKLRVEPAKLVMTDGEKKKLGQDLMALEEDFPQKIADLLREQSGSDGQSGEGEIEIDIEALSDEILFMVRKLLDDYLREKKKSMEKSEPCEMEIVHDSGFSNSPLQPSKGDLQIDEDVDIVGGNDPSVSSHPPLKIEKDAACRNNESSSSSSSSSESGSSSSDSDSCSSSGSETDSIKASKPTSREEKKQPGVGIDKKEDDSNSEKIVVNDSLNELDQLEHTVGEKSTTMDAVVLVPDEETAPPERQISPDSPDKRYRAAFLKNRFADTIMKAREKAFTKGEKGDPEKLRIEREEFEKRLREEKERLQAEAKAAEEARRKAKAEAAEKARREREQEREAARQALQKMEKTVEINEGIRFMEDLQMLRATGTEGDQLPTSMEVMSPKFSEDMLGLGSFKMESNSNPLEHLGLYMKMDEDEDEEEDPPHFSQRKVEDNPFDRSEKQEHSPHRVEGEDQLVSGNEEPVSQEAHDNGDQEDGKPINPNEIERQLENMPEQESGVGDKEEQETEVVDMRKQENEVVDMGVEEVHPLDRSEGRTLSPHRKEREDPRASGNEESVSEKAQDYENQRDEKINQSEREEQLENVLEQESSRDDDTGEQETEVVGVGKELSLDKSEGQTLSPHREEGENQLDCGNEELVSQKTQDNGNQEDEKSINKIEGEEQLANVPEQESRVTEKEEQETGVVDLGEQKSEVVEKGVEENEAVDNGEGVQGTEVSDKGGNETVVDGNGKVETEVVDKAGQKTDLVDQGEEDIDVEID
Protein: Sushi repeat-containing protein SRPX2 (Sushi-repeat protein upregulated in leukemia) (O60687)
Organism: Homo sapiens (Human)
Function: Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.
Subcellular location: Secreted {ECO:0000269|PubMed:22242148}. Cytoplasm. Cell surface. Synapse {ECO:0000250}.
Interaction partners:
- Urokinase plasminogen activator surface receptor
- Annexin
- Hepatic leukemia factor
- Urokinase-type plasminogen activator
- Transcription factor E2-alpha
- A disintegrin and metalloproteinase with thrombospondin motifs 4
Sequence:
MASQLTQRGALFLLFFLTPAVTPTWYAGSGYYPDESYNEVYAEEVPQAPALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEPVTPEEIFTFIDDYLLSNQELTQRREQRDICE
Protein: Chloride channel accessory 3A2 (A0A0G2JGF3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
PSRMIVYVRVSQGFLPVLGANVTAIIEAEHGHQVTLELWDNGAGADTVKNDGIYTRYFTDYHGNGRYSLKVRVQARKNKARLSLRQKNKSLYIPGYVENGKIVLNPPRPDVQEEAIEATVEDFNRVTSGGSFTVSGAPPDGDHARVFPPSKVTDLEAEFIGDYIQLTWTAPGKVLDKGRGESNGEFKML
Protein: Galanin receptor type 2 (GAL2-R) (GALR-2) (O08726)
Organism: Rattus norvegicus (Rat)
Function: Receptor for the hormone galanin, GALP and spexin-1. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Galanin peptides
- Spexin
- Galanin receptor type 1
- Galanin receptor type 3
- Galanin-like peptide
- Pro-neuropeptide Y
- Galectin-2
Sequence:
MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTLDPAC
Protein: Ribosomal RNA large subunit methyltransferase G (EC 2.1.1.174) (23S rRNA m2G1835 methyltransferase) (rRNA (guanine-N(2)-)-methyltransferase RlmG) (P42596)
Organism: Escherichia coli (strain K12)
Function: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Ribosomal RNA small subunit methyltransferase D
- Ribosomal RNA large subunit methyltransferase K/L
Sequence:
MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
Protein: Geranylgeranyl diphosphate synthase (GGPP synthase) (GGPS) (EC 2.5.1.29) (O50410)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the condensation of isopentenyl pyrophosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield geranylgeranyl diphosphate (GGPP).
Interaction partners:
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1
- 
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2
- Dimethylallyltranstransferase
- 
- Nonaprenyl diphosphate synthase
- 
- Type B diterpene cyclase
- Isopentenyl-diphosphate Delta-isomerase
- Tuberculosinyl adenosine transferase
Sequence:
MGGVLTLDAAFLGSVPADLGKALLERARADCGPVLHRAIESMREPLATMAGYHLGWWNADRSTAAGSSGKYFRAALVYAAAAACGGDVGDATPVSAAVELVHNFTLLHDDVMDGDATRRGRPTVWSVWGVGVAILLGDALHATAVRILTGLTDECVAVRAIRRLQMSCLDLCIGQFEDCLLEGQPEVTVDDYLRMAAGKTAALTGCCCALGALVANADDATIAALERFGHELGLAFQCVDDLIGIWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAATELAALYQAPAAMTASDVERATALVKVAGGGHVAQRCADERIQAAIAALPDAVRSPDLIALSQLICRREC
Protein: Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)] (P27930)
Organism: Homo sapiens (Human)
Function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Subcellular location: [Isoform Short]: Secreted {ECO:0000269|PubMed:8702856}.; SUBCELLULAR LOCATION: [Isoform Long]: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Interleukin-1 beta
- Interleukin-1 alpha
- Interleukin-1 receptor accessory protein
- Interleukin-1 receptor type 1
- Interleukin-1 receptor antagonist protein
- Interleukin-10
- Tumor necrosis factor
- Interferon gamma
- Interleukin-6
- Interleukin-6 receptor subunit alpha
Sequence:
MLRLYVLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK
Protein: Myocyte-specific enhancer factor 2C (Myocyte enhancer factor 2C) (A0A096MJY4)
Organism: Rattus norvegicus (Rat)
Function: Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:15862299}. Cytoplasm, sarcoplasm {ECO:0000269|PubMed:15862299}.
Interaction partners:
- Transcription factor GATA-4
- Homeobox protein Nkx-2.5
- T-box transcription factor TBX5
- Myoblast determination protein 1
- Myogenin
- Calcineurin-binding protein cabin-1
- Catenin beta-1
- Histone deacetylase
- Histone deacetylase 4
- Heart- and neural crest derivatives-expressed protein 2
Sequence:
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLCAVPPPNFEMPVTIPVSSHNSLVYSNPVSSLGNPNLLPLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNIQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRYPQHTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPSPDERESPSVKRMRLSEGWAT
Protein: Glucocorticoid receptor (Nuclear receptor subfamily 3 group C member 1) (E5KQF6)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTHSDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK
Protein: histidine--tRNA ligase (EC 6.1.1.21) (Q9VWT1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSDTREQILEQIKVQGDLVRQLKAAKESKEKIDEEVARLLALKATLGGDAAPTNQKFTLKTPKGTRDYGPQQMTLRQGVLDKIVQVFKRHGGEAIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVIKLNHRQLLDGMFQACGVPADSFRTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLSGGAELVEQLLANEKLKAVPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGESATVASPAKTSQQNGEQANEPATVGSVAGGGRYDNLVGMFDPRGKAVPCVGVSIGVERIFSVLEARAAASGLKLRTSDVEVYVASAHKGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCEEHQIPLVVVLGDAELAQGLVKLREVTTREETNVKLEDLAAEIRRRQQASA
Protein: Photosystem II 22 kDa protein, chloroplastic (CP22) (Protein NONPHOTOCHEMICAL QUENCHING 4) (Protein PHOTOSYSTEM II SUBUNIT S) (Q9XF91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays an important role in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. Is not necessary for efficient light harvesting and photosynthesis.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:10667783}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Chlorophyll a-b binding protein CP26, chloroplastic
- Chlorophyll a-b binding protein 3, chloroplastic
- Photosystem I reaction center subunit V, chloroplastic
- ATP synthase gamma chain 1, chloroplastic
- Oxygen-evolving enhancer protein 1-1, chloroplastic
- Chlorophyll a-b binding protein
- Oxygen-evolving enhancer protein 3-1, chloroplastic
- Light-harvesting complex-like protein 3 isotype 2, chloroplastic
- Protein CURVATURE THYLAKOID 1B, chloroplastic
- Chlorophyll a-b binding protein 2.1, chloroplastic
Sequence:
MAQTMLLTSGVTAGHFLRNKSPLAQPKVHHLFLSGNSPVALPSRRQSFVPLALFKPKTKAAPKKVEKPKSKVEDGIFGTSGGIGFTKANELFVGRVAMIGFAASLLGEALTGKGILAQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGKFVDDPPTGLEKAVIPPGKNVRSALGLKEQGPLFGFTKANELFVGRLAQLGIAFSLIGEIITGKGALAQLNIETGIPIQDIEPLVLLNVAFFFFAAINPGNGKFITDDGEES
Protein: Uncharacterized protein C27E2.11c, mitochondrial (Q9UTA0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Large ribosomal subunit protein bL33m
- NAD/NADP-dependent indole-3-acetaldehyde reductase
- Putative ATP synthase subunit epsilon, mitochondrial
Sequence:
MYSRVLSVAAIVTMALAVQAANSTAPYGNTTNSTGTTNGTNGTNTTTSSTATQSSAASITNFSSGAFVIAMIAVACSVMSL
Protein: Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (Zinc finger DHHC domain-containing protein 17) (A5WVX9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). Plays a role in axonogenesis.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8IUH5}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q8IUH5}; Multi-pass membrane protein {ECO:0000255}. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q8IUH5}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Palmitoyltransferase
- Palmitoyltransferase ZDHHC22
- Huntingtin.
Sequence:
MADALVGYEKEAGCVPILHPEEIKPQSHYNHGYNESRKSHVDDYSTWDIVKATQYGIFERCRELVEAGYDVRQPDKENVTLLHWAAINNRVDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCVHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEANANVDAQNIKGETPLDLAKQRKNVWMINHLQEARQAKGYDSPSYLKRLKMDKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGVMYAVMWLVVQFLSKSFFDHSMHSALPLGIYLATKFWMYITWFYWFWNDLPFVTIHLPFLLNSLALFYNFGKSWKSDPGIIKASEEQKKKTIVELAETGSLDLSIFCSTCLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRYFMGYLFFLLCMICWMMYGCICYWRIHCATSYTKDGFWIYITQIATCSPWMFWMFLNSVFHFMWVAVLIMCQLYQIAVLGITTNERMNARRYKHFKVTATSIESPFNHGCMRNLIDFFELRCCGLLRPVPIDWTSQYTIEYDQTSGSGYQLV
Protein: Protein regulator of cytokinesis 1 (SPD-1) (G5ED58)
Organism: Caenorhabditis elegans
Interaction partners:
- Kinesin-like protein
- Kinesin-like protein
- Rac GTPase-activating protein 1
- Kinesin-like protein
- Calponin-homology
- Aurora/IPL1-related protein kinase 2
- Kinesin like protein
- Kinesin-like protein klp-19
- Incenp-like protein ICP-1
- Kinesin motor domain-containing protein
Sequence:
MSRRHSVVDAYSTVEGKIRDTMRELSALWDEVDMSEAMRLKRVDNAFTHITLLCDDMLSGEKEMIHNLKVSIREDMQNVKKMRLELEMEDFQRPAEIKDGSIALMRHLQSEVKSLETEFQTRHEDQRVLIEKICNLKKRLESDFEFEYEIHALFPVKAFEKYSASCSEMEELLKHRYHQIERLQTDISQWKSMAQNVADYIGGDDDLKNLLEKNIDSPEFVFSERLLDSLQSYHSELEPLYKHWLEDIEFRWTEKHQQLQELWEKCLVSEADRHYSPIFEPTKNSEQTLKRMEDECDRLEKKYEACRIVFELVDKWRAVWTEKLTIDEKRKQPNYYKTTNVLPDNKRERELLNQMPVLERKIDSAHRKYGNEHDGEQISIQGMAPLEYVRFVQEEHKRELKFELQLKKEEKTRMQSPTPTRTPRTQKRAMFRTPMSTAKMEPVAKKLNFDTDLPPCMSPATSEMISFITPTRRQAVGPKTSSPKDTQPSTSSSSRTTTPMSKRAMTPSSIASSTPSSAKKVLTRRNQFL
Protein: tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase) (Q9Y7T3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
Interaction partners:
- Histidine--tRNA ligase, mitochondrial
- Probable methionine--tRNA ligase, mitochondrial
- Putative tRNA pseudouridine synthase C16C4.06c
- tRNA N
- tRNA
- tRNA
Sequence:
MAKSRFEYVKQYERLDRLLPETYIVIRIDGKGFHKFTKKHDFEKPNDLRCLNLMNAAARVVMSEFTDIVLAYGDSDEYSFVWSKSTELYERRESKLVSHVCSLFTSAFVFNWPKHFDIPLLSLPSFDGRAVLYPNMKVLRDYLHWRQVDCHINNLYNTTFWMLILKGGFTNTQAEEYLKGTVSAEKHEILFSKFGINYNFEPEIYKKGSIWIREPIDQEWHQQDKKFSVKQKKKMVLSILHVSLIDDDFWTSRPFLEVLLQ
Protein: histidine kinase (EC 2.7.13.3) (Q1D1K8)
Organism: Myxococcus xanthus (strain DK1622)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- DNA-binding response regulator
- DNA-binding heavy metal response regulator
- Response regulator
- DNA-binding response regulator
- Chemotaxis protein CheY
- histidine kinase
- histidine kinase
- DNA-binding response regulator
- Response regulator
- DNA-binding response regulator PhoP2
Sequence:
MKRGRPRAHKRGWDAWGEPRECGPWGHRHPPHGYWHMGRLGGFVRARLHRRLFMWFGLSILATGAVVATVMSLVGGGTWKQEGDRVRAFVGHRFEEVWDEPARRDALVASIEKDLQVGVELRDASGAMLAQSQVPCRRPELNLPVVRDGITLGSVRACYASFRPKNPLRMVLPLALSCMVLWLASGKLARRLARPMDALVRATRELGSGRLDSRADVAPHVTGEFAVLADAFNDMAGRIEKQVADQRELLAAVSHELRTPLARLRVLTELLRDGGGNPKTLDQVDREVVELDALVGELLASSRLDFGQLTPRVLDGQTLATQALERAGLASSLLGMDVERAGLVGDATLLGRALANLLENARKHGTGAEALRIQERGEHLAFCVEDRGPGLQPGEDERIFRPFYRRDQGTEAREAGSLGLGLALVQRIAHVHGGDVFAENRPGGGARVGFTVRKNGPPASEGRPTA
Protein: Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (GAP SH3 domain-binding protein 1) (HDH-VIII) (P97855)
Organism: Mus musculus (Mouse)
Function: ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also RIGI-induced type I interferon production probably by helping RIGI at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:15086518, ECO:0000269|PubMed:8649363}. Perikaryon {ECO:0000269|PubMed:15086518}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q13283}. Nucleus {ECO:0000250|UniProtKB:Q13283}. Note=Cytoplasmic in proliferating cells, can be recruited to the plasma membrane in exponentially growing cells. Cytosolic and partially nuclear in resting cells. Recruited to stress granules in response to arsenite treatment. The unphosphorylated form is recruited to stress granules. HRAS signaling contributes to this process by regulating G3BP dephosphorylation. {ECO:0000250|UniProtKB:Q13283}.
Interaction partners:
- Caprin-1
- Cytotoxic granule associated RNA binding protein TIA1
- Ubiquitin carboxyl-terminal hydrolase 10
- Nucleolysin TIAR
- GTPase KRas
- GTPase HRas
- GTP-binding protein REM 1
- Ras GTPase-activating protein 1
- Eukaryotic translation initiation factor 3 subunit B
- ELAV-like protein 1
Sequence:
MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQTVSNDLEEHLEEPVVEPEPEPEPEPEPEPVSDIQEDKPEAALEEAAPDDVQKSTSPAPADVAPAQEDLRTFSWASVTSKNLPPSGAVPVTGTPPHVVKVPASQPRPESKPDSQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGPSGGMRGPPRGGMVQKPGFGVGRGITTPRQ
Protein: Forkhead box P, isoform D (IP01211p) (Q9VH87)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
Sequence:
MHRIHDDEYSEDAKESDFKSSIQKEISVKSRHQISIPDICSDAVKNNCFPPTGFLNNSITFASHVVKCSSPASSIDESSTAAQQHESNPHMHIQGQHMMAPVPDLGFYNVPEFISEQEKLMFSDAERFLRSKDNEVCNNDFSYMHDEFAMRKYYHPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQAMMHHLYLSKQLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRPIRQTNSPSPLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAVRHNLSLHKCFMRVENVKGAVWTVDEIEFYKRRPQRTAGIGNNLTGATNSPDTNYFVAMNIGYVGLK
Protein: Probable conserved transmembrane protein alanine and leucine rich (P72045)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter RfbE
- Probable O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter RfbD
- Galactofuranosyltransferase GlfT1
- Bacterial proteasome activator
- Possible conserved membrane protein
- Possible transferase
- Uncharacterized protein Rv0048c
- Uncharacterized protein Rv0875c
- Possible membrane acyltransferase
- Uncharacterized protein Rv3630
Sequence:
MGLWFGTLIALILLIAPGAMVARIAQLRWPVAIAVGPALTYGVVALAIIPYGALGIPWNGWTALAALAVTCAVATGLQLLLARFRDLDAEALAVSRWPAVTVAAGVLLGALLIGWAAYRGIPHWQSIPSTWDAVWHANTVRFILDTGQASSTHMGELRNVETHAPLYYPSVFHGLVAVFCQLTGAAPTTGYTLSSLAASVWLFPVSAAVLTWRAVRSHPGALWSASCASAEWRAAGAAGTAAALSASFTAVPYVEFDTAAMPNLAAYGIAVPTMVLITSTLRHRDRIPVAVLALVGVFSLHITGGIVVALLVSAWWLFEALRHPVRSRLADLLTLAGVAAMAGLVMLPQFLSVRQQEDIIAGHAFPTYLSKKRGLFDAVFQHSRHLNDFPVQYALIVLAAIGGLILLVKKIWWPLAVWLLLIVMNVDAGTPLGGPIGGVAGALGEFFYHDPRRIAAATTLLLMLMAGVALFATVMLLVAAAKRLTDRFRPQPVSVWASATATLLIGATLVSAWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYLASLPGARDTLIGNANTDGTAWMYAVAGLHPLWTHYDYPLQQGPGYHRFIFWAYGRNGESDPRVLEAIQVLRIRYILTSTPTVRGFAVPDGLVSLETSRSWAKIYDNGEARIYEWRGTAAATHS
Protein: Palustrin-2AJ2 (G3F828)
Organism: Amolops jingdongensis (Chinese torrent frog)
Function: Displays broad-spectrum antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Has low hemolytic activity, low cytotoxicity and low antioxidant activity (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:21816202}.
Interaction partners:
Sequence:
MFTLKKPLLVLLFLGTVSLSLCEQERAADDDEGEVIEEEVKRGFMDTAKQVAKNVAVTLIDKLRCKVTGGC
Protein: 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (KPHMT) (P9WIL7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Pantothenate synthetase
- Aspartate 1-decarboxylase
- 2-dehydropantoate 2-reductase
- Dihydroxy-acid dehydratase
- Branched-chain-amino-acid aminotransferase
- Conserved hypothetical alanine and leucine rich protein
- Pup--protein ligase
- Uncharacterized protein Rv2226
- Proteasome-associated ATPase
- GMP synthase
Sequence:
MSEQTIYGANTPGGSGPRTKIRTHHLQRWKADGHKWAMLTAYDYSTARIFDEAGIPVLLVGDSAANVVYGYDTTVPISIDELIPLVRGVVRGAPHALVVADLPFGSYEAGPTAALAAATRFLKDGGAHAVKLEGGERVAEQIACLTAAGIPVMAHIGFTPQSVNTLGGFRVQGRGDAAEQTIADAIAVAEAGAFAVVMEMVPAELATQITGKLTIPTVGIGAGPNCDGQVLVWQDMAGFSGAKTARFVKRYADVGGELRRAAMQYAQEVAGGVFPADEHSF