wanglab/gogpt-training-data huggingface dataset:
Protein: Ncx4a (Sodium/calcium exchanger 4 isoform a) (Solute carrier family 8 member 4a) (Solute carrier family 8 member 4a precursor) (A4UQV6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Dynamin 1a
- V-type proton ATPase subunit a
- E2 ubiquitin-conjugating enzyme
- Troponin I, fast skeletal muscle
- Inositol-pentakisphosphate 2-kinase
- Protein phosphatase 1, regulatory
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase catalytic subunit alpha
Sequence:
MFHLRLSRSSFSSITPCLSSVLLLIFLSGLTHLSQASGDVSHSGPGNCSGEDSCSEGVVLPIWNPQNPSVGDKVARAIVYFVALIYMFLGMSIIADRFMSSIEVITSQEKEITIKKPNGETTTATVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHKFEAGHLGPSTIVGSAAFNMFIIIALCVYVVPDGEVRKIKHLRVFFVTAAWSIFAYIWLYLILSVFSPGVVEVWEAVLTFLFFPLCVVQAWIADRRLLFYKYVHKRYRTDKNRGIIIETEGDGMFTKMDMEMDGQGANSHHKEALDGMLAGVEEGGGGGEEEEARREMARTLKELKQRHPEKDMEQLIEMANYQVLVQQQKSRAFYRIQATRMMIGAGNILKKHAADQARKVVSCHEANPQEEDPHTIYLEFEPSHYQCFENCGSLKLSVTRHGGDSGCTVKVDYRTEDGTANAGSDYEFAEGTLVFKPGETVKELTVGVIDDDIFEEDEHFYVHLSNPRVVHRAEVSILDPNAVSPGNSIIGSSHVPPKAALGNAHSATVTIYDDDHAGIFTFESNSTRVSESVGIMQVKVHRTSGARGKVAVPYHTTEGTAKAGEDYDEVAGKLEFLNDETMKILEVKIIDDEEYEKNKTFTIHLGEPVLLEIGQKHGDSNDNKPAVGAEEEEVAKMGCPSLGEHTKLEVVIEESYEFKNTVDKLIKKTNLALVVGSSSWREQFVSAVTVSAGDDDEEESGEERLPSCFDYIMHFLTVFWKVLFAFVPPTEYWNGWACFIVSITLIGVLTAVTGDLASHFGCTVGLKDTVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWTIAAVYWHSQGKKFQVPPGSLAFSVTLFTILALVCVVTLLYRRRPSVSGGELGGPRTPKLLTAFLFIVLWLIYIMLASLEAYCHVPGF
Protein: Long-chain-fatty-acid--CoA ligase ACSBG1 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 1) (Gonadotropin-regulated long chain acyl CoA synthetase) (GR-LACS) (Q924N5)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11381125}. Cytoplasmic vesicle {ECO:0000250}. Microsome {ECO:0000250}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q96GR2}. Cell membrane {ECO:0000250|UniProtKB:Q96GR2}.
Interaction partners:
- Fatty acid synthase
- Palmitoyl-protein thioesterase 1
- Lysosomal thioesterase PPT2
- Lipoprotein lipase
- Carnitine O-palmitoyltransferase 1, liver isoform
- Fatty acid CoA ligase Acsl3
- Long-chain-fatty-acid--CoA ligase 6
- Palmitoyl thioesterase CPT1C
Sequence:
MPRSSEAGYCCLSRDSNMPDSRDDQQQGASMGTSPDNSQTSSLIDGRTLSKESPSHGLELSAPEKARAASLDASEEALWTTRADGRVRLRLEPFCTQLPYTVHQMFYEALDKYGNLSALGFKRKDKWERISYYQYYLIARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAHDCRANVIVVDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIELGQEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFADPDALKGTLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNFYGAAPMTAETQRFFLGLNIRLYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKLVNQDADGIGEICLWGRTIFMGYLNMEDKTHEAIDSEGWLHTGDMGRLDDDGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLNPETSEPTDNLTEQAVEFCQRVGSKASTVSEIVGQKDEAVYQAIHEGIQRVNANAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKDIIDSFYQEQKQ
Protein: Rho GTPase-activating protein 29 (Rho-type GTPase-activating protein 29) (Q8CGF1)
Organism: Mus musculus (Mouse)
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho (By similarity). In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.
Interaction partners:
- Ras-interacting protein 1
- Cell division control protein 42 homolog
- Transforming protein RhoA
- Tyrosine-protein phosphatase non-receptor type 13
Sequence:
MIAHKQKKAKKKRVWASGQPSAAITTSEMGLKSVSSSSSFDPEYIKELVNDVRKFSHMLLYLKEAILSDCFKEVIHIRLDELLRVLKSILSKHQNLSSVDLQSAAEVLTAKVKAVNFTEVNEENKNDIFREVFSSIETLAFTFGNILTNFLMGDVGSDSILRLPISRESKSFENISVDSVDLPHEKGNFSPIELDNLLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRSSIGIQEFMPLQSLFTNALLSDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKDLWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLAKNLNKQLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKATSSSELEEKVDGNVNKQMTNSPQTSGYEPADSLEDVARLPDSCHKLEEDRCSNSADMTGPSFVRSWKFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNSLGAFKKTLMSKAALTHKFRKLRSPTKCRDCDGIVMFPGVECEECLLVCHRKCLENLVIICGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEVNRILLKSKDLLRQLPASHFNSLHYLIAHLRRVVDHAEENKMNSKNLGVIFGPTLIRPRPTTAPVTISSLAEYSNQARLVEFLITYSQKIFDGSLQPQAVVISNTGAVAPQVDQGYLPKPLLSPDERDTDHSMKPLFFSSKEDIRSSDCESKSFELTTSFEESERRQNALGKCDAPLLDNKVHLLFDQEHESASQKMEDVCKSPKLLLLKSNRAANSVQRHTPRTKMRPVSLPVDRLLLLASSPTERSSRDVGNVDSDKFGKNPAFEGLHRKDNSNTTRSKVNGFDQQNVQKSWDTQYVRNNFTAKTTMIVPSAYPEKGLTVNTGNNRDHPGSKAHAEPARAAGDVSERRSSDSCPATAVRAPRTLQPQHWTTFYKPPNPTFSVRGTEEKTALPSIAVPPVLVHAPQIHVTKSDPDSEATLACPVQTSGQPKESSEEPALPEGTPTCQRPRLKRMQQFEDLEDEIPQFV
Protein: Evasin P974 (A0A023FDY8)
Organism: Amblyomma cajennense (Cayenne tick) (Acarus cajennensis)
Function: Salivary chemokine-binding protein which binds to host chemokines CCL1, CCL3, CCL4, CCL8, CCL17, CCL18 and CCL22.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MKVLLCIAASCLMLLALNVSAENTQQEEQDYDYGTDTCPFPVLANKTNKAKFVGCHQKCNGGDQKLTDGTACYVVERKVWDRMTPMLWYECPLGECKNGVCEDLRKKEDCRKGNGEEK
Protein: Small ribosomal subunit protein eS19B (40S ribosomal protein S19-B) (S16-B) (P79016)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS9A
- Elongation factor 3
- Small ribosomal subunit protein eS7
- mRNA export factor elf1
Sequence:
MAGVSVKDVDAQQFINAYAAFLKRSGKMTTPQWIDIVKTGTHKELAPYDPDWYYVRAAAIARHIYLRKQVGVGRLCKVYGGSVNRGMRPSHHRDGSGSVQRKVVQSLEKIGVLEKSDNGGRRISQQGQRDLDRIAYSLLEDEE
Protein: Transport protein particle subunit trs31 (TRAPP subunit trs31) (Q9P7N9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: TRAPP plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
Subcellular location: Golgi apparatus {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Interaction partners:
- Uncharacterized protein C13G6.05c
- Transport protein particle subunit trs120
- Transport protein particle 20 kDa subunit
- Uncharacterized protein C15A10.12c
- Transport protein particle subunit bet3
- Transport protein particle subunit trs23
- Transport protein particle subunit bet5
- Uncharacterized protein CC285.14
- GTP-binding protein ypt1
- Transport protein particle subunit trs85-2
Sequence:
MQSTNKELFRSSVSESLKSTAPLMGKSVYEQNLNKIRNSDVNLSSFAFIFSELIQRIQSQVSGIQEFEEKLNEHGYRVGQKLVELVVWRERNPKRETRILGILQYIHSSVWKYLFGKHADSLEKSKEASDEYMIVDNNPLLNKFISVPKEMNQLNCCAYLAGIIEGFLDSAQFPCKASAHSVPLSQYPYRTVILIKLDPSVIAREEVLG
Protein: glutathione transferase (EC 2.5.1.18) (E7EZ94)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Glutathione S-transferase
- Glutathione S-transferase omega 1
- glutathione transferase
- Maleylacetoacetate isomerase
- Glutathione S-transferase rho
- Glutathione S-transferase omega 2.
- Glutathione S-transferase
- Glutathione S-transferase kappa
- Microsomal glutathione S-transferase 2.
Sequence:
MPLELYLDLHSQPCRSVFIFAKINKIPFEYKAVDLSAGEQYGDEFGKVSIIRKVPALKDGDFLLTESIAILLYLAGKHSTPDHWYPADLQKRAQVDEFLSWQHTNIRSHGSKVFWFKGVLPAVTGAPVPKEKMDSALEDLNMSLKIFEDKFLQSRPFIIGDKISLADIVAIVEMMQPVATGVDVFEGRPALSAWRDRVKKEVGVELFDEAHKVIMNVESLPQTFENKGLPEFFKLKIQKMFN
Protein: Transcription factor MYB108 (Myb-related protein 108) (AtMYB108) (Protein BOTRYTIS-SUSCEPTIBLE 1) (Q9LDE1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor contributing to the regulation of stamen maturation and male fertility in response to jasmonate signaling. Required for correct timing of anther dehiscence. Acts as a negative regulator of abscisic acid-induced cell death. Not involved in the regulation of BOI. Regulated by MYB21 and at a lower level by MYB24. Negatively regulated by the proteasome in an SCF(COI1) E3 ubiquitin-protein ligase complex-dependent manner.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:20921156}.
Interaction partners:
- E3 ubiquitin-protein ligase BOI
- NAC domain-containing protein 3
Sequence:
MDEKGRSLKNNNMEDEMDLKRGPWTAEEDFKLMNYIATNGEGRWNSLSRCAGLQRTGKSCRLRWLNYLRPDVRRGNITLEEQLLILELHSRWGNRWSKIAQYLPGRTDNEIKNYWRTRVQKHAKQLKCDVNSQQFKDTMKYLWMPRLVERIQSASASSAAAATTTTTTTTGSAGTSSCITTSNNQFMNYDYNNNNMGQQFGVMSNNDYITPENSSVAVSPASDLTEYYSAPNPNPEYYSGQMGNSYYPDQNLVSSQLLPDNYFDYSGLLDEDLTAMQEQSNLSWFENINGAASSSDSLWNIGETDEEFWFLQQQQQFNNNGSF
Protein: Innexin (C8JQR8)
Organism: Caenorhabditis elegans
Subcellular location: Cell junction, gap junction {ECO:0000256|ARBA:ARBA00004610}. Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU010713}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU010713}.
Interaction partners:
Sequence:
MILYYLASAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNNVDRSPTQFWDAEHGQGTID
Protein: Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein) (P07197)
Organism: Homo sapiens (Human)
Function: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P08553}. Cell projection, axon {ECO:0000250|UniProtKB:P08553}.
Interaction partners:
- Neurofilament light polypeptide
- Alpha-internexin
- Neurofilament heavy polypeptide
- Kinesin-1 heavy chain
- Kinesin heavy chain isoform 5C
- Kinesin heavy chain isoform 5A
- Kinesin light chain 1
- Kinesin light chain 2
- Kinesin light chain 3
- Kinesin light chain 4
Sequence:
MSYTLDSLGNPSAYRRVTETRSSFSRVSGSPSSGFRSQSWSRGSPSTVSSSYKRSMLAPRLAYSSAMLSSAESSLDFSQSSSLLNGGSGPGGDYKLSRSNEKEQLQGLNDRFAGYIEKVHYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIVKEVTQSD
Protein: Uncharacterized protein (Q580D1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQSPSAFVAAADQSNYRVPDAQLATCTKHGGAAVLCATAGKVGRNGRTAAVGATLFWLTCPYLNTIVARFERHSAISALQRLLDNDRKVSEAHVASHARYEERAKELLSSERWAFFDAHFVTGAAESAGGRKYGNAAVSHATDLKCLHALVAQSLCGASNPIGDAVIHYILLLAEKVKTIKNASAPLSSEKGSSGDCSTAEVCGGENSFAAESLALDEVSLLVEFVKQRLTDDIRGDRSDLRSVHDADKLCSSACEVLTFLDGRPPRSRKKHRIN
Protein: Photosystem I reaction center subunit II-2, chloroplastic (Photosystem I 20 kDa subunit 2) (PSI-D2) (Q9SA56)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PSAD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center. PSAD may encode the ferredoxin-docking protein (By similarity).
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Stromal side {ECO:0000250}.
Interaction partners:
- Photosystem I reaction center subunit psaK, chloroplastic
- Photosystem I reaction center subunit IV B, chloroplastic
- Photosystem I P700 chlorophyll a apoprotein A1
- Photosystem I reaction center subunit IV A, chloroplastic
- Photosystem I reaction center subunit III, chloroplastic
- Photosystem I reaction center subunit XI, chloroplastic
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I iron-sulfur center
- Photosystem I reaction center subunit VI-2, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 3-1, chloroplastic
Sequence:
MATQAAGIFSPAITTTTSAVKKLHLFSSSHRPKSLSFTKTAIRAEKTESSSAAPAVKEAPVGFTPPQLDPNTPSPIFAGSTGGLLRKAQVEEFYVITWNSPKEQIFEMPTGGAAIMREGPNLLKLARKEQCLALGTRLRSKYKITYQFYRVFPNGEVQYLHPKDGVYPEKANPGREGVGLNMRSIGKNVSPIEVKFTGKQSYDL
Protein: Probable ATP-dependent RNA helicase DHR1 (EC 3.6.4.13) (DEAH box RNA helicase DHR1) (Extracellular mutant protein 16) (Q04217)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable ATP-binding RNA helicase. Required for 18S rRNA synthesis. May play a role in restructuring of the pre-rRNA.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:10982841}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 6
- Nucleolar protein 6
- Nucleolar protein 58
- KRR1 small subunit processome component
- Essential nuclear protein 1
- Ribosomal RNA-processing protein 9
- Periodic tryptophan protein 2
- U3 small nucleolar RNA-associated protein 16
- U3 small nucleolar RNA-associated protein MPP10
- rRNA processing protein RCL1
Sequence:
MGTYRKRFNEKARSGHMAKLKELKRIRNKQFTRQDENDERVENPDSAPAESSTTEPNANAEILEPLTEEEKKMKKRKLQELFTPKESKVSRLKKKRLDKFIEHQLKREERKTIIGKLQDYKIDTSLLTSSKRLGEGRQTKKEEFKEALSLERQGRGNEQTNEILYEEYEPKVWDEYGEGGSSEDDDGEDDFEASFGSMPKPTDNEEKKSSGFIDHRPAKFGGSGLSFGFSNIKVINKESKTPKKKYNWRQRVEMEELKKHGKEDEMDFDTTSEDDDEEEDQEEEDKMHPSENPLEEVESADSETGSEKFDQNDVANEFKDWANQEIKKLEGRDQELVTPTLNIDYKPIIRKEDLDDGLQEAYVPINENSTRKAFYVEVSRSDEIQKARIQLPVFGEEHKIMEAIHHNDVVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGMVGITQPRRVAAVSMAERVANELGDHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLTKYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATLRVSDFSENKTLFPIAPPVLQVDARQFPVSIHFNRRTAFNYTDEAFRKTCKIHQKLPPGAILVFLTGQQEITHMVKRLRKEFPFKKNSKYNKDLETPVSKMGINSKTTDLEAEDIDFSVQVIDQDKFKSAIRYEEDEGNSGNGEDEEDEEEEGFEEVLTEGQTANDPLYVLPLYSLLPTKEQMRVFQKPPQGSRLCIVATNVAETSLTIPGVRYVVDSGRSKERKYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDFEQFSKPEILRMPVESIVLQMKSMAIHNIINFPFPTPPDRVALSKAIQLLQYLGALDNKEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSALSVGDPFINEFELGINEISRKPNPDENLDDKIREHDESTPGMDPELKKELRSKFYKSRSQFSKLDKFSDVFRLLSVVSAMDYVPKEQKEIFMKKNFLRGKLMEEIVKLRKQLMYIIKSNTSKENIAVVIRNEDLKSDIPSVIQIKLLKQMICAGFVDHVAVRADVLFPDDAKITNRTSIINIPYIPVLATRTPNIEDCFVYIHPTSILNNLGEMPPKYMLYYSLHLGGNNKTRMNTLCDIASTPLANIARKGLLLTYSKPLTGQGLKTVNLSPTERYCYVVPRFGSTVDNDLKIGWDLNPIAVHQKKQKGQWTVIKFITRKGFQTITGEEKEKK
Protein: Uncharacterized protein C12G12.16c (Q09708)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- DNA polymerase delta catalytic subunit
- Inheritance of peroxisomes protein 2
- Proliferating cell nuclear antigen
- DNA ligase 3
- DNA ligase 1
- DNA replication ATP-dependent helicase/nuclease dna2
- Double-strand break repair protein rad32
- DNA damage checkpoint control protein rad1
- General transcription and DNA repair factor IIH subunit tfb1
Sequence:
MGVHGLLPIIRKVASEGIRWLQPEFFSKYYPVLAVDGNLLLYRFFRSPNTPLHTNYQHVLWALKLSRYCRKLKTSPIVVFDNLKPNDFKAEEHEKRSLISSQIVNQRQVVQEQMYFLCNLKNCLIDNNFPTGNFYYEIGPLLSQIGKLLFDLRSLNERDNPFHAQNNAENLENATFVRLIVDKLNDREKTLMIQEKKNHLIHSLRQLLAFSEINDFPSEIRSYLEFILSNLDLECLTLCLKIIKGILTLDELQKAIKLKQTELDKLERRLYRPSPQNIFEIFEILKILGIPASFSPIGVEAEAFASAISQNNLAYAVATQDTDVLLLGSSMISNFLDLNDNFHLPLQIMDPRKIAQELNLTFDGFQDYCLMCGTDFTSRIPKIGPVRALKLIRYYGNAFDVLKALNVEEKYIIPTDYIKKFLTAKKLFTDLPSNNELFSFIHNIPKEFLHLSDSTYLDLEKQVLRIFNVQIEELDAKTPWYYHYELEKDVKSTYEY
Protein: TOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B) (Q6A070)
Organism: Mus musculus (Mouse)
Function: Involved in ciliogenesis. It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (By similarity). Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:26378256}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:26378256}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9Y4F4}. Note=Detected along the length of primary cilia and at the basal body. Colocalization with the cytoplasmic microtubule cytoskeleton upon heterologous expression is most likely an artifact. {ECO:0000269|PubMed:26378256}.
Interaction partners:
Sequence:
MAAAPSELLPLPPPATPGSYRLLSRCRPYAPGTDGRRSGGTMRGEKNYYCRGAAGDHGSCPATPSPLASTLLLPAEAVSTSWSGPGSGLSGGDEEETRLLQLLRTAPDPSEAFQALQAALPRRGGRLGFPRRKEALYRALGRVLVEGGSEEKRLCLQLLSDVLRGQGEAGQLEEAFSLALLPQLVVSLREDNPALRKDALQILHICLRRSSGQVLRTLIQGLESPDARLRASTALLLPILFTPEDLLQGLDLTEVIISLARKLGDQEMEEESETAFSSLQQIGERLGQERFHSYISRLPSALRRHYNRRLESQYGSQVPYYLELEASGFSEDAAPCVVNLSSSNLKFEIIPQELHARLLDQEDYKNRTQAVEELKQLLGKFNPSSTPHASLVGFISLLYNLLDDSNFKVVHGTLQVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQRVLSLLLENLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFAVLASSMGSGKTNVLFKAVDTVELQDNGDGVMNAVQARLARKTLPRLTEQGFVEYAILMPSSAQGRSSHLAHGADTDWLMSGNRTQSAHCYCGDHTRDSMQLYGSYSPTICTRRVLSAGKGKNKLPWENEQPGVMGENQTSNSKDIKDTEQFSAHDLIPSPKLKPSQGMPASDDLCFSKKRSSRNLFQSSRDFNSESVPTCGAGNTADLQTNLPGKCGQLGLSQIGCRTGSVGSDLQFLGTANGHQDKVYASIDFGSKTQQTFGSQSERTSSYSGSNASPGSFILPSYPLASPRTSPKHTSPLSVAPKKSQDNSISFSNSWPLKSFEGLSKPSPQKKLANQKSSDPTGENFQEKTTAVQLTPALVRSPSSRRGLNGTKPVPPIPRGINLLPDKADLSTMGHMKKQPDDIWKSEKDNLTIDLSELNFRDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSSSTSDVDSPDSAMKLELTIDSPSRASSPNISSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCSTRLSSAKKTSHAAEQSPSAGFTRSSNLQQISSFDFTSTNTLSEDSVVIVGKGVFGNPNSAPTTCSQPVISSVESEDTFPVKPSIEPPSGVYGRAVQHNAPLYPEVENDKDTKVSIAKSTYEKMRQKRKEEKELLDAKDCERKETNPWERIKHLGSEKMTSENEPSSGVIPQYKERMSSVTHSPEIMDSLELRPFSKPDIALTEALRLLADEDWEKKMEGLNFVRCLAAFHSDLLNTKLHETTFAVVQEVKNLRSGVSRAAVVCLGDLFTYLKKSMDQELDSAVRALLHKAGESNTFIREDVDKALKAMVNNVTPARAVTSLINGGQSHLHIAVRRCTAQHLADVVECMDPERISSGTKDMADRLLPAAAKFAQDSSQETRYYGRKMLFLMMGHPNFEKLLEKYIPSKDLPYIKESVKNLRLKGLGEIPLDTASAKGRRSHPGSVGNTRSSSVSRDAFSSSEREVTEVREVPRKSAPRNSLESAEYIKVITGLLNAKDFRDRINGIKQLLSDTENNQELVVGNIVKIFDAFKSRLHDSNSKVNLVALETMHKMIPLLRDNLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVHALSQHVDNYLLLQPFCTKAQFLNGKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMTHSGSLPGAGGNIRTATAKLSKALFTQMGQNLLNQAASQPPHIKKSLEELLDVTVLSEL
Protein: SUZ domain-containing protein (D2KT99)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSKENVSLVVADSWDDADADPVKELMDKVEKVKLLQRKEEKKEAFFEKVKAEESSGVVSKLQTEEGLGPSAEEPKRVFLRRPKDGFAASENVIEASPPTSADTEEQPVTNVRSRSHHKLNQKEKQPAPTYEERQAAYQAARNRILGTEYKPDNQEIKEIKFIDRSKSPETLKMTQQNMVEHYGEELSRELMEQPAEIVPPERQYTPDFTNYIPYNLPNMAYPPPNFQPQGQLHHQMNAGQLHQIQQQQQQCQQIQHQPPQQHQQVINGQVMNQQNQRNQVNSYPQQNGAGRGQNRQPMMYQMPCNSGPTAKPPPLMNQMQNRCMTNNGQNYQNRNMQQQGQQRSYSSQPQNGQFYQNGNSNQNNPNNGRKQQHQPQQQQNKSGKFGQNRNDMQKNNYQPNLQQPPMSQNPIPFGCPPRNVNAIREQHANNGSPNTGAGILGPHPMMSASQWPALQQNRPQ
Protein: Mitochondrial Rho GTPase (MIRO-1) (EC 3.6.5.-) (Ras homolog gene family member T1) (A1L1L6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8IXI2}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q8IXI2}. Note=Colocalizes with MGARP and RHOT2 at the mitochondria. {ECO:0000250|UniProtKB:Q8IXI2}.
Interaction partners:
Sequence:
MRAGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNESGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIVCDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSVSPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR
Protein: Cohesin loading complex subunit SCC4 homolog (V9GZ52)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
AIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEVHPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTISTLHDDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKSKSVLDCSPILSSFQVILLEHIIMCRLVTGHKATALQEISQVC
Protein: Collagen alpha-5(IV) chain (P29400)
Organism: Homo sapiens (Human)
Function: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane.
Interaction partners:
- Collagen alpha-6
- Beclin-1
- CD44 antigen
- Platelet glycoprotein VI
- Collagen alpha-3
- Collagen alpha-4
- Collagen alpha-2
- Nuclear protein AMMECR1
- Procollagen galactosyltransferase 2
- Collagen alpha-2
Sequence:
MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQVCMKRT