wanglab/gogpt-training-data huggingface dataset:
Protein: Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (G4SRS5)
Organism: Caenorhabditis elegans
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
- Iron-sulfur cluster assembly 1 homolog
- 2Fe-2S ferredoxin-type domain-containing protein
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- GST_C_6 domain-containing protein
- cysteine desulfurase
- Transmembrane protein 50A
- NFU1 iron-sulfur cluster scaffold homolog
- ABC transporter domain-containing protein
- Inositol-pentakisphosphate 2-kinase
- ABC transporter domain-containing protein
Sequence:
MLQLRLIAGLRNASNTIRSQAVYRSFSSLTKSPALIRNATQILSKNKRAVVQVFTRTCFHPGASSQVPLQASGQLSGYQLVQRLLKFVWPKDKPEIKRRVLVALCLLIAAKLANVSVPFLLRDIVNYYNGKAPEFLKLTFDGTPSQTIFTAGIATCIAYGIARATASLFNELRNAVFAKVAQNSIRSISRSIFLHLHSLDLSFHLNRQTGALSKAIDRGTRGMSFVLSSLIFNLIPTAVEIGMVSALFTGTLGPEFAYMTMGSIGMYGIATLGVTKWRTKFRHQMNQADNDAGNKAIDSLINYETVKYFNNEKFEADRYDHFLKKYEGASLKTTSSLALLNFTQNAIFSGALIGVMCMAGTRIAAGDLTIGDLILANTLLFQLSIPLNFLGSVYREVRQGLVDMNQMFSLLTLKPKIVEAADAKRLEIVDNDISLKFENVHFGYLPEKPILKGLDLEIPVGKKVAIVGGSGSGKSTIVRLLYRLYDTESGNVRINGLETRDLTLDSLRQSISIVPQDSVLFHDTIFYNLAYGRPSASMEEVYQAAKLADLHESVLAMPNGYETLVGERGLKLSGGEKQRVAIARAILKNAPFVIYDEATSSLDAITESNIMKALKGAVEKRTSLFIAHRLATIVDADIIYVLQDGKVAEKGSHFDLLAVDGLYAQLWKSQNIHGVAPKKSKEEDDDLMLELDLDKCCGSSSCNR
Protein: Lantibiotic lacticin 3147 A1 (O87236)
Organism: Lactococcus lactis subsp. lactis (Streptococcus lactis)
Function: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually lacticin 3147 A1 exhibits strong activity towards L.lactis strain AM2, weak activity towards L.lactis strain HP and no activity towards L.lactis strain IFPL359, but when combined with lacticin 3147 A2 it displays strong activity towards all three strains.
Subcellular location: Secreted {ECO:0000269|PubMed:10608807, ECO:0000269|PubMed:10971756}.
Interaction partners:
Sequence:
MNKNEIETQPVTWLEEVSDQNFDEDVFGACSTNTFSLSDYWGNNGAWCTLTHECMAWCK
Protein: T-cell antigen CD7 (GP40) (T-cell leukemia antigen) (T-cell surface antigen Leu-9) (TP41) (CD antigen CD7) (P09564)
Organism: Homo sapiens (Human)
Function: Not yet known.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- T-cell surface antigen CD2
- Secreted and transmembrane protein 1
- T-cell surface glycoprotein CD5
- Aminopeptidase N
- Low affinity immunoglobulin gamma Fc region receptor III-B
- T-cell surface glycoprotein CD4
- Neural cell adhesion molecule 1
- T-cell differentiation antigen CD6
- Myeloid cell surface antigen CD33
- Low affinity immunoglobulin gamma Fc region receptor III-A
Sequence:
MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALPAALAVISFLLGLGLGVACVLARTQIKKLCSWRDKNSAACVVYEDMSHSRCNTLSSPNQYQ
Protein: Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein) (P31209)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Eukaryotic translation initiation factor 4 gamma
- Eukaryotic peptide chain release factor GTP-binding subunit
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-splicing factor cwf14
- U2 small nuclear ribonucleoprotein A'
- Putative ATP-dependent RNA helicase ste13
- Pre-mRNA-splicing factor brr2
- Probable heat shock protein ssa2
- G-patch domain-containing protein C1486.03
- ATP-dependent RNA helicase eIF4A
Sequence:
MPSTDLKKQADAAVESDVNTNNEAVESSTKEESSNTPSTETQPEKKAEEPEAAAEPSESTSTPTNASSVATPSGTAPTSASLYVGELDPSVTEAMLFELFNSIGPVASIRVCRDAVTRRSLGYAYVNFHNMEDGEKALDELNYTLIKGRPCRIMWSQRDPSLRKMGTGNVFIKNLDPAIDNKALHDTFSAFGKILSCKVAVDELGNAKGYGFVHFDSVESANAAIEHVNGMLLNDKKVYVGHHVSRRERQSKVEALKANFTNVYIKNLDTEITEQEFSDLFGQFGEITSLSLVKDQNDKPRGFGFVNYANHECAQKAVDELNDKEYKGKKLYVGRAQKKHEREEELRKRYEQMKLEKMNKYQGVNLFIKNLQDEVDDERLKAEFSAFGTITSAKIMTDEQGKSKGFGFVCYTTPEEANKAVTEMNQRMLAGKPLYVALAQRKEVRRSQLEAQIQARNQFRLQQQVAAAAGIPAVQYGATGPLIYGPGGYPIPAAVNGRGMPMVPGHNGPMPMYPGMPTQFPAGGPAPGYPGMNARGPVPAQGRPMMMPGSVPSAGPAEAEAVPAVPGMPERFTAADLAAVPEESRKQVLGELLYPKVFVREEKLSGKITGMLLEMPNSELLELLEDDSALNERVNEAIGVLQEFVDQEPGFTE
Protein: Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) (P33527)
Organism: Homo sapiens (Human)
Function: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation. Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:16230346, ECO:0000269|PubMed:31273342}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:9426231}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Broad substrate specificity ATP-binding cassette transporter ABCG2
- Small ribosomal subunit protein uS7m
- Major vault protein
- Leukotriene B4 receptor 2
Sequence:
MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV
Protein: Rho-related GTP-binding protein RhoU (Rho GTPase-like protein ARHU) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1) (Q9EQT3)
Organism: Mus musculus (Mouse)
Function: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q7L0Q8}; Lipid-anchor {ECO:0000250|UniProtKB:Q7L0Q8}; Cytoplasmic side {ECO:0000250|UniProtKB:Q7L0Q8}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q7L0Q8}; Lipid-anchor {ECO:0000250|UniProtKB:Q7L0Q8}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q7L0Q8}. Cell projection, podosome {ECO:0000250|UniProtKB:Q7L0Q8}. Note=Localizes to podosomes in SRC-transformed cells. {ECO:0000250|UniProtKB:Q7L0Q8}.
Interaction partners:
- Serine/threonine-protein kinase PAK 4
- Intersectin-2
- Cytoplasmic protein NCK2
- Intersectin-1
- SH2/SH3 adapter protein Nck1
- Serine/threonine-protein kinase PAK 1
- Growth factor receptor-bound protein 2
- Partitioning defective 6 homolog alpha
Sequence:
MAPQQGRPALPARCEPPAAPPVPPRRERGGRGARGPGVSGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPTSFQNVGEKWVPEIRRHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEVKAVSYIECSALTQKNLKEVFDAAIVAGIQHSDSQLQPKKSKSRTPDKVRDLSKSWWRKYCCLA
Protein: Somatoliberin (Growth hormone-releasing factor) (Growth hormone-releasing hormone) (A0A181)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Growth hormone-releasing hormone receptor,-like
- Growth hormone-releasing hormone receptor a
- Vasoactive intestinal peptide receptor 2
- Adenylate cyclase-activating polypeptide 1a
- Pro-thyrotropin-releasing hormone
- Vasoactive intestinal peptide receptor 1a
- Vasoactive intestinal peptide receptor 1b
- Appetite-regulating hormone isoform X1
- Corticotropin-releasing hormone a.
- Corticotropin-releasing hormone b.
Sequence:
MQVGVIQRTALLVLCCLLLSASSSPVYPALKFGRHADAIFTNSYRKVLGQISARKFLQTVMGKRLGPETESNVKRQSSMYGNTYKQDVDMNVIESEQSYRDPQKFKFALIMH
Protein: Heterogeneous nuclear ribonucleoprotein R (Q8VHM5)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein L
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoproteins C1/C2
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Serine/arginine-rich splicing factor 1
- Serine/arginine-rich splicing factor 3
- Heterogeneous nuclear ribonucleoprotein Q
Sequence:
MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPMRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK
Protein: Gamma-aminobutyric acid type B receptor subunit 1 (H2L0Q3)
Organism: Caenorhabditis elegans
Function: Component of a heterodimeric G-protein coupled receptor for GABA, formed by gbb-1 and gbb-2 (By similarity). Within the heterodimeric GABA receptor, only gbb-1 seems to bind agonists, while gbb-2 mediates coupling to G proteins (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase (By similarity). Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis (By similarity). Calcium is required for high affinity binding to GABA (By similarity). Plays a critical role in the fine-tuning of inhibitory synaptic transmission (By similarity). Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials (By similarity). Along with gbb-2, may couple to the G(o)-alpha G-protein goa-1 to negatively regulate cholinergic receptor activity in the presence of high levels of acetylcholine in ventral cord motor neurons. As acetylcholine depolarizes body wall muscles, modulation of acetylcholine levels most likely results in the control of locomotory behavior. Acts in neurons to regulate lifespan, and this may be through G-protein-egl-8/PLC-beta signaling to the transcription factor daf-16/FOXO.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9UBS5}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Gamma-aminobutyric acid type B receptor subunit 2
- Muscarinic acetylcholine receptor gar-2
- Muscarinic acetylcholine receptor gar-3
- Gamma-aminobutyric acid receptor subunit beta
Sequence:
MFVRSSWLLLWGTIVWASAEPVTLHIGGTFPMESGSGGWAGGEACLPAVEMALKDVNSRLDILPGYVLNMTNHNSQCQPGLAMQQLYDFLYKPPTKLMLLTGCSPVTTVIAEAAPVWKLVVLSYGGSSPALSNRNRFPTLFRTHPSANMQNPTRIHIMEKFKWKRFTILMSVEEVFVTTAKDLEAIARKKGIKVDRQSFYGDPTDAMKTLQRQDARIIVGLFYVTEARKVLCQAYHHGLYGRRYVWFFIGWYADTWYIPPPEEHLNCTAEQMTEAAEYHFTTESVMLSRDNIPAISEMTGMQFQQRLTQYFQKDTANVGGFPEAPLAYDAVWALALAFNCTRNNLPSHIRLENFTYDNKVIADTLFQCVKNTSFRGVSGKVMFSDSGDRIARTQIEQMQGGKYKIMGYYDTTSGDLEWYNKEQWLNGKGPPPDSTVIKKHAMTVSNEFYYPTILFAVLGIAACVFIYLFTQKHHERLIIFQSQPECNNILLIGCSLCLFSLFLIGLPSDDISISESLFPLLCHARVTILLFGFTFAYGSMFAKVWIVHRMGATENQQLASRQKDEEENTPWEGIRTLISTMVGRQALMRKSSGQAYGALLEKRNTVLNQPISSSKFYVIVAALTAVDVFVCFVWVLIDPLHLTEQKFPLFTPADSEEDEMIMPVLQQCQSNQQEVWIGIIMGFKCLLLVFGTFLSYETRNLKLRFINDSRFVGLAIYNVAVMTLVTAPVVTLLIHGKVDANFAFISLTVLICTYISVGLIYGPKIRHIIKVPPSADEIQLNGNVGPGVMSKVDQKRYDMLKKENETLQIQIEEKERKIHECKERLEELTKNSETEDMNAQLLCENDKQIADENLTYSTATTLTTTIPLIDLQNGNHPGQIYENDNDDDGSSTSSDEILL
Protein: Murein hydrolase activator EnvC (Septal ring factor) (P37690)
Organism: Escherichia coli (strain K12)
Function: Activator of the cell wall hydrolases AmiA and AmiB. Required for septal murein cleavage and daughter cell separation during cell division. In vitro, exhibits weak endoproteolytic activity on beta-casein.
Subcellular location: Periplasm {ECO:0000269|PubMed:12113939, ECO:0000269|PubMed:15165230, ECO:0000269|PubMed:19525345}. Note=Localizes at the septal ring.
Interaction partners:
- Cell division protein FtsX
- N-acetylmuramoyl-L-alanine amidase AmiB
- Uncharacterized protein YibQ
- N-acetylmuramoyl-L-alanine amidase AmiA
- Cellulose synthase operon protein C
- Cell division ATP-binding protein FtsE
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Sequence:
MTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADERDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKKTLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR
Protein: BcDNA.GH04120 (Uncharacterized protein, isoform A (EC 3.2.1.52)) (Uncharacterized protein, isoform B) (Q9VEB8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Probable beta-hexosaminidase fdl
- beta-N-acetylhexosaminidase
- beta-N-acetylhexosaminidase
- Alpha-
- IP11976p
- Latrophilin Cirl
Sequence:
MHSNLWIFIWRRKLSFLLVVSGLVLLGLWTWAILIDTTASAQPPAAPISNSERQQQQQQSTGYQQVHIIQKLIEQANRVLRAERLKDNAVEKSPSPVQRLGNVRSLRPTQAKKAPLPMSESFLFEQERLKILEQQQRQRNAGMEELNANAEDERMLSSAERQTQYEHELQRMGVPVVAGIGPDGPRAPAERLVHLDLKGAPPKLSFLKQLLPVLRALGATGLLIEYEDMFPYSGVLQPLAAHNAYKEDELRDFLECAALHGLSVMPLVQTFGHMEYVLKLSGFEQLRELAESPQSICPSQPQSMALLEQMLTQVIELHSQCLGQATPATNVPVARIRFTHIHIGCDEVQRMGECTTCRQRLRSELFLSHVVSMAHFIRRQWPHLGVVIWDDQLRSMSLSELQHSQVGSYVEPMVWVYASDIYRFIQPQLWDTYAKVFPSAWTASAFKGAFGESLLVPPLQHHLENNIRWLAVIAKEGGRFSKGLRGLALTGWQRYDHFAVLCELLPVGIPSLMTSLSTVSKGYFSTNPRDNELLRVLQCVFQPDSRRSGRPWLELHPNAHHSQLFAVCNYPGHLVFKYALRLFDKLAEIRLYLQQTRDQSAWLSDYNVRHNFSSPLRVRELTARTPMLIEELRAMAREAQQLLWEVYDEYTVTEFVEQHIYPTIEALQRQLARAEMLLQRRTWPQRPLPLPLKVQEDMGLVTHQQEQQ
Protein: RE54856p (Q8MQY7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSVWSDCNAKQAEFGIAKCNFDQESKPHRLNLDVGDAVIILKETAHWYYGYRQKAKEIRGIFPKSYIHLCEYNIVNGEYCIQRTDIVEEITKVLLEWGSIAKDYFLTTNPSFPKIRRKMNELNNNRAALISGNLPLDEVRKVKLLATNQIDTGNKLLGLDMVVRDESGDILDTNAICTTELYEQHMHAVQRIDKANRLSSERGTTRTPNKYSHNILLHVNAFVCKFQEDSDLLFTLFDGETHKPISENYVVKWSRTGIARDTDQIDNNRVLFTDLSKSDLAIAKMYLVCYAIRIGSMEFKDSAESKRTSMSIANSMLNASSRKASQLSVSSSGSSSSNGEYIIRRPFGVACKDLTPFINKSDDFRGNIDLPFIMCEKETLDGTLRKLIANKDIGKIDSKMAVTIEVLRGDIKQIKEEFPRLMHTNVPVARKMGFPEVILPGDVRNDLYLTICSGEFARIAKTSEKNVEVSVCVANEQGYLMPGVLSIGAGHQPIDEYKSVVYYHDDKPKWQETFKIHVPIEDFKQCHLRFVLKHRSSNEQKDRTEKPFGLAYVRLMQANGTTITQGQHILAVYKIDHKKYDKTVANCYLELPATVAELQGAKPSIGGLTLLPKDQLSIGVNLCSTKLTQSVSLLGLLNWSAHKETLEQSLNALSTVPGEEVVKFLQDILDALFNILVENDHPEKYDQLVFMSIIHLIETVSDLKYQHFLSVLDVYINESFSFTLAYTKLMDVLQKNISEAISPKEKSADGNDLEESPEVRRLYKTTRYLRYVMKFVIRSRVLYAEMNCNTDYMDFATRLQELLRMFIDMIGCPSNLLKSEGALLKNLHIIATDLMQVFEHVRLSISIVEILEKFPPRRLTQSKMGCIKDFVETKLFTLPKCRAILLPVFCKHIKDHLESKEEIAECINIMNNILKLLFRSDVGSTHNDIRDIMIILFRTVMKAAHALDRDTGLVGKFFAIMLGILQRMDAQHYEYFVKDLHQSGELKHFVIEILLVFEELVSPHQKAVFPRDWMDMIMHQNTVILGALKHLTVVITDYFLCPFEKQIWSNFFQCSIAFLVQSPLQLNDFNDNKRQIVFARYRDIRKDTAMEIRKMWFQLGQHKPKFVPQLVEPILEMSMIPEKELRQETIPIFFDMMQCEYYSSRLEHESYGDTKFNNAHHKGNFSDFKTAMIEKLDILIGAGKGDAEYKHLFETIMLERCAAHNTLNVDGTAFVQMVTRLMDKLLEYRFIIQDESKENRMACTFSLLQFYSEVDLKEMYIRYVNKLCALHMEFENYTEAAFTLKLHTELLRWTDTELSHQLRSYRHNNCRTHRQLKEALYFEIMEYFDKGKQWECAIDMCRVLARQYEEEIFDYLKLAELLNRMALFYEKIIKELRHNSEYFRVCFYGRGFPRFLQNRVYIFRGKEYERHSDFCARMLVQHPQAELMQTLEAPGDDITNSDGQYIQVNKVEPIMGQAFNKFNDKIINNEIVKYFTANNVQKFQFSRPFRDSTNGGDRDDVRNLWLERTELRISYPLPGILRWFPVVETNTFKISPLEQRSKL
Protein: Putative cyclic nucleotide-gated ion channel 7 (Cyclic nucleotide- and calmodulin-regulated ion channel 7) (Q9S9N5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative cyclic nucleotide-gated ion channel.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative respiratory burst oxidase homolog protein J
- Putative respiratory burst oxidase homolog protein H
- Glutamate receptor 3.7
- Glutamate receptor 1.2
- Glutamate receptor 1.4
- Glutamate receptor 2.1
Sequence:
MYKSQYISGQREKFVRLDDIDSSSSPATGMMMQRNCFGFNLKNRGGEKKKASKSFREGVKKIRSEGLITIGKSVTRAVFPEDLRITEKKIFDPQDKTLLVWNRLFVISCILAVSVDPLFFYLPIVDNSGSSCIGIDTKLAVTTTTLRTIVDVFYLTRMALQFRTAYIAPSSRVFGRGELVIDPAKIAERYLTRYFVVDFLAVLPLPQIAVWKFLHGSKGSDVLPTKTALLNIVIVQYIPRFVRFIPLTSELKKTAGAFAEGAWAGAAYYLLWYMLASHITGAFWYMLSVERNDTCWRFACKVQPDPRLCVQILYCGTKFVSSGETEWIKTVPELLKSNCSAKADDSKFNYGIYGQAISSGIVSSTTFFSKFCYCLWWGLQNLSTLGQGLQTSTFPGEVLFSIAIAIAGLLLFALLIGNMQTYLQSLTVRLEEMRIKRRDSEQWMHHRSLPQNLRERVRRYDQYKWLETRGVDEENIVQSLPKDLRRDIKRHLCLNLVRRVPLFANMDERLLDAICERLKPSLFTESTYIVREGDPVNEMMFIIRGRLESVTTDGGRSGFFNRGLLKEGDFCGEELLTWALDPKAGSNLPSSTRTVKALTEVEAFALEAEELKFVASQFRRLHSRQVQQTFRFYSQQWRTWASCFIQAAWRRYSRRKNAELRRIEEKEEELGYEDEYDDESDKRPMVITRSESSSRLRSTIFASRFAANALKGHRLRSSESSKTLINLQKPPEPDFDAE
Protein: RE07880p (Q5BIA1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLWIVFWLAVLWLWHEAKIPQETRPIASSANPAPAGITRSVRSCNCCPYGYHIDLDFVRYCEALALEKPSEEEQRRRDRRRSRKSMEFMLGFESLFGGDWQAESRVQGKLSETSHESEPDSPHPIGGGGSLHMSQSYTTTPCYRPRSSSVPRFTYGSIPPRSESPFGTASSTCSSLRGGVESDAGIYHQRHRPAISPPETRAFLHEALDEVCSDFERTLERTSVKRRKSPYGAGSLSMDRNNNKLSLSISNGHGALKELKSHRLGNSTWDRHFDVADSCIGGNQSPTGTPRPFLRSNTLPLRQRPSPAEVQYESYVQATVAANAKSPVEQLESAKSPGAPPPPPPRRHHLLATTPTGKPTFKEDRPQENGSVSSSSLQSPVISETGQTTADAQALFQIREQMALSLRRLKDLEEQVKVIPDMELELNSLRSEKQKLLRRNEELMRSQRQTPSPPSPGLKTASPVQFTPQRISPVSLESLGARMRSSSTSASPSPSVVRRDVSTQAVVRPPATRDVSVGHQPTTRNVGVQPSETVYSKEELDKKVEQALTNAQKQQLRKLISVGTQMYVPQRDQKDSGVQTTPERPKLKYHVGVTVKPATRENFTSCKPDVRHVGSSDDRLDDVLCEKCAVSKRSVACGPETPAEKVKPAPQMPGRSNTFSLGENETVSVVRKTIGCQTPVTLVLSSGSQTTTAVVRSTGAQVNPQQQHSGVQCATEQVSRQTDTKGLQRLTRSQTKAEQVSESVPRPTTRHTASNTDKVEEAEPAKVRTSHSACNTEEVRKRDVGCGDIVKPHISIACAANYCDSCKEAIQDLARGFSKASPTATRTGGAVRRSTSADSRIPRPKHLSSPSPVRKEFMRQNTYTLATPSPTPSPQVERKARLSSLQEKPPSVSSFQASEPLPESQSFIRQPQKDSLDLSLLGEDELIVREEKRVSISWSRDASPAPLMTSSGTTKSESPEQEPAMSSSSDSSPPIDVQIAQGARKKSSTPLKSSQSEGSQVTVIEQPATKAQLHQLAQADSEPRKKTELSQSLRDALKIINDSLLKKLGAKPISSQSLKSAKATIQDHWFTNSSTGKSDPHQVEDYLDYFESLSIPLLEYCVNLSDSNGNTAMHYAVSHGNFDVVSILLDSKVCDVNQMNNAGYTSVMLASLAKLKQPAHRTVVERLFKMADVNIRAKKHCQTALMLAVSHGNGDMVNMLLDAGADINIQDEDGSTALMCAAEHGRVDVIKHLLSHPECDSLVTDVDGSTAFKIAWQAGHRDVGLLIYVHEQMLRSKLPNRGDATRSSLISPPRHKRQPSQ
Protein: Repression factor of MSEs protein 1 (Q12192)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Tethering factor required for histone deacetylase HST1-mediated repression. Probably involved in targeting HST1 to a subset of SUM1-regulated genes.
Subcellular location: Nucleus.
Interaction partners:
- Suppressor of mar1-1 protein
- NAD-dependent protein deacetylase HST1
- NAD-dependent histone deacetylase SIR2
- Meiosis-specific transcription factor NDT80
Sequence:
MSTNTEIIKNSDLQSLINDKRRLINEIKDFNKSIKPLEFESYQDYFLIKTFKKGISASGHVDIDSLRNKEYGIYYKKIKRNSTQEVGEPIPRNTSSSSSSTRSNSSADISDTEYSGENTPTTTGAASRRRRTRSRAIQRENSLPASLPSISEANANNDDVTISEINGSELPFPIPISEVENIDIASDITERDGIRRRSSRISERDKRRSQSRLGSEEDEEGDGHDGDEGETKIQDLYESLVPKILESRRRSDWILPPKARYTPEKQMRTKPSFKSIKINELVGNKRIRSILSRFEGGVAGIRKRDWDSTQ
Protein: D-arabinono-1,4-lactone oxidase (ALO) (EC 1.1.3.37) (L-galactono-gamma-lactone oxidase) (P54783)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Can oxidize L-gulono-1,4-lactone as well as D-arabinono-1,4-lactone and L-galactono-1,4-lactone.
Subcellular location: Mitochondrion membrane. Note=Membrane-embedded.
Interaction partners:
- Probable electron transfer flavoprotein subunit alpha, mitochondrial
- Sorting assembly machinery 35 kDa subunit
Sequence:
MSTIPFRKNYVFKNWAGIYSAKPERYFQPSSIDEVVELVKSARLAEKSLVTVGSGHSPSNMCVTDEWLVNLDRLDKVQKFVEYPELHYADVTVDAGMRLYQLNEFLGAKGYSIQNLGSISEQSVAGIISTGSHGSSPYHGLISSQYVNLTIVNGKGELKFLDAENDPEVFKAALLSVGKIGIIVSATIRVVPGFNIKSTQEVITFENLLKQWDTLWTSSEFIRVWWYPYTRKCVLWRGNKTTDAQNGPAKSWWGTKLGRFFYETLLWISTKIYAPLTPFVEKFVFNRQYGKLEKSSTGDVNVTDSISGFNMDCLFSQFVDEWGCPMDNGLEVLRSLDHSIAQAAINKEFYVHVPMEVRCSNTTLPSEPLDTSKRTNTSPGPVYGNVCRPFLDNTPSHCRFAPLENVTNSQLTLYINATIYRPFGCNTPIHKWFTLFENTMMVAGGKPHWAKNFLGSTTLAAGPVKKDTDYDDFEMRGMALKVEEWYGEDLKKFRKIRKEQDPDNVFLANKQWAIINGIIDPSELSD
Protein: [histone H3]-lysine(27) N-trimethyltransferase (EC 2.1.1.356) (A0A0A0MSY9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQSMKPCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL