wanglab/gogpt-training-data huggingface dataset:
Protein: U-box domain-containing protein 17 (EC 2.3.2.27) (Plant U-box protein 17) (RING-type E3 ubiquitin transferase PUB17) (Q9C7R6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as an E3 ubiquitin ligase.
Interaction partners:
- BTB/POZ domain-containing protein POB1
- CF9 protein
- Squamosa promoter-binding-like protein 11
- Probable inactive ATP-dependent zinc metalloprotease FTSHI 1, chloroplastic
- Exocyst complex component EXO70B2
Sequence:
MASAAIFSSLRRRRSPSLEAFLAPVDLSGVALVQTLASISSEVVSCFTSVRFSFQRKNARSLIRKIEIFVVLFEFLVDSNWGSTTTRTRARRRSKSSVSESTALLCLKELYLLLYRSKILVDYCAQSSKLWLLLQNPSISGYFHDLNQEISTLLDVLPVNDLGLSDDIREQIELLQRQSRKARLYIDKNDESLRESFYSFLDGFENGKIPSSVDLRMFFVEKLGIRDSKSCRSEIEFLEEQIVNHDGDLEPTGSVINGFVAITRYCRFLLFGFEEDGMEWWIENNPKKPRKGFVAQEIGDTFITVPKDFVCPISLDLMTDPVIISTGQTYDRNSIARWIEEGHCTCPKTGQMLMDSRIVPNRALKNLIVQWCTASGISYESEFTDSPNESFASALPTKAAVEANKATVSILIKYLADGSQAAQTVAAREIRLLAKTGKENRAYIAEAGAIPHLCRLLTSENAIAQENSVTAMLNLSIYEKNKSRIMEEGDCLESIVSVLVSGLTVEAQENAAATLFSLSAVHEYKKRIAIVDQCVEALALLLQNGTPRGKKDAVTALYNLSTHPDNCSRMIEGGGVSSLVGALKNEGVAEEAAGALALLVRQSLGAEAIGKEDSAVAGLMGMMRCGTPRGKENAVAALLELCRSGGAAVAEKVLRAPAIAGLLQTLLFTGTKRARRKAASLARVFQRRENAAMRSGVYGFVGNTNGNRDGGFTTDVSVPISISISVPVL
Protein: GTP-binding protein (A0A1D8PI64)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- GTP-binding protein
- Serine/threonine-protein kinase TOR
- Ubiquitin-binding TORC1 subunit
- Nitrogen permease regulating protein
- Nitrogen permease regulator 3
- Restriction of telomere capping protein 1
- Vacuolar membrane-associated protein IML1
- Uncharacterized protein
- UDENN FLCN/SMCR8-type domain-containing protein
- GTPase
Sequence:
MSTSASSRKKLLLMGRSGSGKSSMRSIIFSNYSALDTRRLGATIDVELSHLRFLGNMTLNLWDCGGQTVFMDNYFTNQKDHIFKMVQVLIHVFDVESKSINKDIEIFIKSLTNLQQYSPGAKVFVLLHKMDLVQIDKRQELFEIMMEKLQKISNPYHFKLIGFPTSIWDESLYKAWSQIVCSLIPNINLFNNNLIEFNSILDAEEIILFEKTTFLVISSTASIQQQQQQQQQQQQQQQQQQQQQQQQQKSIDNDQDSTNEELDPKRFEKISNIIKTYKQSITKLRTNFKNLIIRGSNGTNFYIDIITDNMFIMIVLKDKKDTQNMIQQHEELLILDNIKAARRWFEKIENNE
Protein: Aluminum tubes, isoform A (Aluminum tubes, isoform B) (Aluminum tubes, isoform D) (Aluminum tubes, isoform E) (Aluminum tubes, isoform F) (Aluminum tubes, isoform H) (Q9VEH0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDFHILIVIGCVVSASLLSFLFINKIFRRKTFEEVVAEKRALSANLYKAAGGAATKKPKKKELKREKKQRQREQQRDVNNEPEPEEAEDYSDGQSEGQGSVAGEEPGLSKQHVEFEPDAEVLTDQRRPSSVAEKENQPSGAGKKGKKDKRNGANNKTAGILVNKNETVAVKPAANAEETPTLNNFETKIPKDVVELKKQEQKERKEDNNNKQQSQKKIAGGNVSKKEKVVAVETEAPVVTKQILKQQQQQQNGSPKTQHNQANNKTKQQQQNKKQNQKETLTGKDLAHALDKLADHQNQTIGVNALMNVFSRAELNRSEIQILIDYLLNKQQDMPASHSEWSDDICQKLKRQLEEKEKLLAEEQEASIGIQAKLRELRQEVNTERAQMHARNQAYIDKLQGKEQELAALNQELSSLNDKLTLERQQLTTLRREKQANSQDLVQLQHLQQDLAHKEKCLAEMTAFVNAETQQKNEVIQQQAQQLQALELQREELEARQNNSIFELEQRKQLEAENADLKQELSAVQQTQSELQRVHAAELQELRQNLSVLEARNVALSQQLTQAANSAVQATAAQSEQAQVQTEALAQKQQELSALRSQVGSLTDAHAQQQKQANALQSQLQEAQQRAEQLQAKEQHLQQELQEQREKNNQQHKELQLQQQKAVAANGGGSASSAKSEQQRIRDLYQRLYPDAVKAQSGNALQASFDQWLEQVLATHVKQQQDKLRQKLDAEKSEKQSSSSHKSTQSSNSSSSNHNSTHNNISSNNSSSNSQSSSAAEQQELHKQNLQLRECNDKLTQLVTKTTNTLMDLEERAREQDEHWRGIVEQKEQLILTLQQHASNGE
Protein: ATP synthase subunit delta, mitochondrial, putative (EC 3.6.3.14) (Q8IHP4)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}.
Interaction partners:
- ATP synthase subunit C, putative
- ATP synthase subunit beta
- ATP synthase subunit gamma
- ATP synthase subunit alpha
- ATP synthase subunit epsilon, mitochondrial, putative
- ATP synthase subunit O, mitochondrial, putative
- JmjC domain-containing protein, putative
- V-type proton ATPase proteolipid subunit
- V-type proton ATPase 21 kDa proteolipid subunit, putative
- Cytochrome c1, putative
Sequence:
MFYRTRRIFFSTAKNSNLYLSISSSSESIFRNQVIKRASFPGIEGYFTVTNNHSPLVTLLRNGIITVEFDDKEKKQFFISDGIFIYKKSNDNNSSNNAEIVGVEIVPLEYLDKNKTIKVLQEMCAINDATDDKWRKIKTLLGKELCSSILRVAT
Protein: Serine-threonine kinase receptor-associated protein (Q9W1N4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RNA helicase
- Serine-threonine kinase receptor-associated protein
- deoxyribose-phosphate aldolase
- Survival motor neuron protein
- Probable small nuclear ribonucleoprotein Sm D1
- N-alpha-acetyltransferase 38, NatC auxiliary subunit
Sequence:
MAANNLRQIPLTCSGHTRPVVHLDFSDICDAGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATLNRNATLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDSENIVTGSNEKLVRVFNLEQPEAQPEEYAGHTGAIKRALFCRGDKCIISAAEDKTVRLWDRMTGIEVQRLQFNSNPNSLEISSDNHILTISHGSSISFWEIDTLKKLKEVKVPTNVASASLHPDKHVFVCGGEDFKMYKFDYITGNEIESFKGHFGPVHSVKFSPDGELYASGSEDGTLRLWQTTVGKTYGLWKCTEPADLGNSISSPREVQAN
Protein: Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG) (Q9UQK1)
Organism: Homo sapiens (Human)
Function: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
Interaction partners:
- Glycogen [starch] synthase, muscle
- Glycogen [starch] synthase, liver
- Laforin
- Protein phosphatase 1 regulatory subunit 3D
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Glycogenin-1
- E3 ubiquitin-protein ligase NHLRC1
- Protein phosphatase 1 regulatory subunit 3A
Sequence:
MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR
Protein: Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10) (E9QJQ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells (By similarity). Essential factor in the regulation of muscle development including myogenesis. Likely plays a key role in muscle cell proliferation, adhesion and motility. May control the balance between skeletal muscle satellite cells proliferation and differentiation through regulation of the notch signaling pathway (Ref.4).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q96KG7}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- receptor protein-tyrosine kinase
- PTB domain-containing engulfment adapter protein 1
- Selenoprotein N
Sequence:
MMSSCGPLLLAVSCCLVALTSSLNLDDPNVCSHWESYSVTVQETYAHPFDQIYYTSCTDILNWFKCTQHRVSYRTAYRRGEKTMHRRKSQCCPGFYESGDICVPHCAEKCVHGRCVAPNTCQCEPGWGGADCSSACDRDHWGPHCSSRCQCKNEALCNPITGACICAPGYHGWRCEDLCDHSTYGNNCQQKCLCQNNATCHHITGECVCSPGYTGAFCEDLCPPGKHGQQCEERCPCQNGGVCHHVTGECSCPAGWGMVCGQPCPTGRFGKNCSQECQCHNGGICSPSTGQCVCSSGYTGERCQDQCQVGTYGIGCSQACRCVNGAQCYHVSGACLCEQGYTGESCEERICPDGQYGLKCDRKCPCNTNNTRSCHPMSGECSCQSGWSGLYCNETCAPGFYGEACQEVCRCQNGADCHSVSGECICAPGYKGSDCAIACPPGTYGINCTSLCSCKNGAICSPIDGSCSCQAGWHGVDCSINCPSGTWGLGCNLSCVCGNGGACNALDGKCTCTPGWRGDRCDQHCQDGTYGLDCRERCDCSHADGCHPSTGHCRCLAGWTGIHCDSVCAEGRWGPNCSLSCNCKNSASCSPDEGACECAPGFRGTTCQHICSPGVFGHRCSQACPHCVHSNGPCHHVTGQCECLPGFKGALCNEVCPSGKFGKNCGGSCTCTNNGTCSPMDGSCQCYPGWIGSDCSQPCPPGQWGPNCIHTCNCHNGAFCSAYDGECKCTAGWTGLYCTQRCPLGFYGKDCVQACQCENGADCNHISGQCTCRTGFMGRHCETKCPAGSYGYGCRQVCDCLNNSTCDHMTGTCYCNPGWKGTRCDQAGGNIAESPNSLTSAALPMDSYQIGAITGIIILVLLVLILLLLFIIYRKKQKGKESSMPSVTYTPTMRANTDYAIAESLPQTEVLPNSNYFSNPSYHTLTQCSSPPHINNIPYGKMNNNQLFVNLKNTEPRKRLSLLDHTGTLPADWKQGGSFSELGAYGVDRRYMGKSLRDLVKSLPYHASSCSLNSSENPYATIKDPPLLLTKSTECGYVEMKSPAHRDSPYAEIHSSSPANKNVYEVEPTISSVQALTNNNCNGPFCQDPYDLPKNSHIPCHYDLLPTRDSSPSPTEDSK
Protein: Chaperone protein SicA (Salmonella invasin chaperone) (P69066)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Type III secretion-associated chaperone required for SipB and SipC stabilization. Prevents premature association of SipB with SipC, which may lead to their targeting for degradation. Along with InvF, required for transcription activation of sigDE (sopB pipC), sicAsipBCDA, and sopE.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- SPI-1 type 3 secretion system translocon protein SctB
- Cell invasion protein SipD
- SPI-1 type 3 secretion system translocon protein SctE
- Cell invasion protein SipA
- Inositol phosphate phosphatase SopB
- SPI-1 type 3 secretion system ATPase
- Protein PrgH
- Surface presentation of antigens protein SpaK
- Invasion protein InvF
- Surface presentation of antigens protein SpaM
Sequence:
MDYQNNVSEERVAEMIWDAVSEGATLKDVHGIPQDMMDGLYAHAYEFYNQGRLDEAETFFRFLCIYDFYNPDYTMGLAAVCQLKKQFQKACDLYAVAFTLLKNDYRPVFFTGQCQLLMRKAAKARQCFELVNERTEDESLRAKALVYLEALKTAETEQHSEQEKE
Protein: Homeobox protein DLX-5 (P56178)
Organism: Homo sapiens (Human)
Function: Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Runt-related transcription factor 2
- Homeobox protein DLX-6
- Bone morphogenetic protein 2
- Homeobox protein MSX-2
- Osteocalcin
- Transcription factor Sp7
- Melanoma-associated antigen D1
- Protein Wnt-3a
- Methyl-CpG-binding protein 2
- Bone morphogenetic protein 7
Sequence:
MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCSPTSASYGKALNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASGTLY
Protein: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) (A0A1D8PQG3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Glucosamine-6-phosphate isomerase
- N-acetylglucosamine kinase 1
- Glutamine--fructose-6-phosphate aminotransferase
- Phosphoacetylglucosamine mutase
- Glucosamine 6-phosphate N-acetyltransferase
- Phosphotransferase
- Hexokinase-2
- Phosphotransferase
- Ngt1p
- Beta-hexosaminidase
Sequence:
MSFTRFTNCHLIDNGELYEFTDLYVNNATKRICHPPANPELVSEVIDLKQQILAPGFIDIQNNGIYGLNFSNLGEESTAEDVAEFKRFYRDAMAKYLSTGVTATCPTVTSSFPEVYAKVLPMYKRSVLASQTDSLGAHVEGPFINVQKKGCHPVETFVDAKEGESKLLEVYGDLFDNVCIVTAAPEIAGVLDLIPVVKSKNCVFSIGHTMSDYDTAVKAVEKGATMITHLYNAMPQPHHRNAGVVGLINSPIVDTPYFGLICDGVHVDPSMVNLAYRSNPSKCVLVTDAMHLIGLPDGHYKWDSQVIVKTGDRLYLENTDTLAGAATTLPQCVRNLVKWSQISLPQAVMTVTNNAAKSIGVDHERGFLNVGCLADFVVLDKSGFVRKVYKLGREVQSSDIPLDRATDKLTAVL
Protein: Cytochrome P450 724B1 (OsCYP724B1) ((22S)-22-hydroxycampesterol synthase) (EC 1.14.14.-) (Dwarf protein 11) (OsDWARF11) (Q6F4F5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in brassinosteroid biosynthesis. May catalyze a C6-oxidation step and may be involved to supply 6-deoxotyphasterol and typhasterol. Involved in internode elongation and seed development. Catalyzes the conversion of campesterol (CR) to (22S)-22-hydroxycampesterol (22-OHCR, 22-hydroxyCR).
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Steroid
- Steroid 5-alpha-reductase DET2
- Os10g0397400 protein
- Cytochrome P450 90A4
- Cytochrome P450 90D2
- Cytochrome P450 90A3
- Steroid 5-alpha-reductase DET2
- Os05g0200400 protein
- Nitrate reductase
- Nitrate reductase 1
Sequence:
MVGGELVLAALVILLALLLTLVLSHFLPLLLNPKAPKGSFGWPLLGETLRFLSPHASNTLGSFLEDHCSRYGRVFKSHLFCTPTIVSCDQELNHFILQNEERLFQCSYPRPIHGILGKSSMLVVLGEDHKRLRNLALALVTSTKLKPSYLGDIEKIALHIVGSWHGKSKDKGMVNVIAFCEEARKFAFSVIVKQVLGLSPEEPVTAMILEDFLAFMKGLISFPLYIPGTPYAKAVQARARISSTVKGIIEERRNAGSSNKGDFLDVLLSSNELSDEEKVSFVLDSLLGGYETTSLLISMVVYFLGQSAQDLELVKREHEGIRSKKEKDEFLSSEDYKKMEYTQHVINEALRCGNIVKFVHRKALKDVRYKEYLIPSGWKVLPVFSAVHLNPLLHGNAQQFQPCRWEGASQGTSKKFTPFGGGPRLCPGSELAKVEAAFFLHHLVLNYRWRIDGDDIPMAYPYVEFQRGLPIEIEPLCSES
Protein: Inner membrane protein YibH (P0AFV0)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Uncharacterized protein YibI
- Uncharacterized protein YbiU
- Macrolide export ATP-binding/permease protein MacB
Sequence:
MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLILLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQARVDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFSERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLEQTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGDDAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPNDDIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH
Protein: Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (mGBP-2) (mGBP2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2) (Q9Z0E6)
Organism: Mus musculus (Mouse)
Function: Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (By similarity). Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity). Confers protection to the protozoan pathogen Toxoplasma gondii.
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000269|PubMed:18025219, ECO:0000269|PubMed:31964735}; Lipid-anchor {ECO:0000250|UniProtKB:P32456}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P32456}; Lipid-anchor {ECO:0000250|UniProtKB:P32456}. Cytoplasm {ECO:0000250|UniProtKB:P32456}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P32456}. Note=GBP2-GBP5 dimers localize to the Golgi apparatus. {ECO:0000250|UniProtKB:P32456}.
Interaction partners:
- Guanylate-binding protein 3
- Guanylate-binding protein 1
- Guanylate-binding protein 5
- Interferon-inducible GTPase 1
- Immunity-related GTPase family M protein 3
- Interferon regulatory factor 1
- Immunity-related GTPase family M protein 2
- Immunity-related GTPase family M protein 1
- Interferon-induced helicase C domain-containing protein 1
- Interferon-induced protein with tetratricopeptide repeats 2
Sequence:
MASEIHMSEPMCLIENTEAQLVINQEALRILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKRTGFSLGSTVQSHTKGIWMWCVPHPKKAGQTLVLLDTEGLEDVEKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSGVDDSANFVGFFPTFVWTLRDFSLELEVNGKPVTSDEYLEHSLTLKKGADKKTKSFNEPRLCIRKFFPKRKCFIFDRPAQRKQLSKLETLREEELCGEFVEQVAEFTSYILSYSSVKTLCGGIIVNGPRLKSLVQTYVGAISNGSLPCMESAVLTLAQIENSAAVQKAITHYEEQMNQKIQMPTETLQELLDLHRPIESEAIEVFLKNSFKDVDQKFQTELGNLLVAKRDAFIKKNMDVSSARCSDLLEDIFGPLEEEVKLGTFSKPGGYYLFLQMRQELEKKYNQAPGKGLQAEAMLKNYFDSKADVVETLLQTDQSLTEAAKEVEEERTKAEAAEAANRELEKKQKEFELMMQQKEKSYQEHVKKLTEKMKDEQKQLLAEQENIIAAKLREQEKFLKEGFENESKKLIREIDTLKQNKSSGKCTIL
Protein: Serine protease 56 (EC 3.4.21.-) (P0CW18)
Organism: Homo sapiens (Human)
Function: Serine protease required during eye development.
Interaction partners:
- Transmembrane protein 98
- Membrane frizzled-related protein
Sequence:
MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQVLSAQGTQALQAAQRSAQWAINRVAMEIQHRSHECRGSGRPRPQALLQDPPEPGPCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSASSSREPSCRELLAWDPPQELQADAARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLRRLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQKLAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGLEPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQP
Protein: Protein-arginine kinase activator protein (P37569)
Organism: Bacillus subtilis (strain 168)
Function: Activates the phosphorylation activity of the protein-arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles.
Interaction partners:
- Transcriptional regulator CtsR
- Protein-arginine kinase
- Negative regulator of genetic competence ClpC/MecB
- Protein-arginine-phosphatase
- ATP-dependent Clp protease proteolytic subunit
- ATP-dependent Clp protease ATP-binding subunit ClpE
- Heat-inducible transcription repressor HrcA
- DNA repair protein RadA
- DNA integrity scanning protein DisA
- Uncharacterized PIN and TRAM-domain containing protein YacL
Sequence:
MICQECHERPATFHFTKVVNGEKIEVHICEQCAKENSDSYGISANQGFSIHNLLSGLLNMDSSFQNAGTQMFSHSEQISACPKCGMTFQQFRKIGRFGCSECYKTFHSNITPILRKVHSGNTVHAGKIPKRIGGNLHVRRQIDMLKKELESLIHQEEFENAAHVRDQIRLLEQSLKSTDSEEEQE
Protein: Erythrocyte membrane protein 1, PfEMP1 (C6KSK8)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MAPQRAEDSNKSAKEVLDEFGQQVYKEKVEKDAKIYKGELEGNLASSSILGETASTDKPCTFEYNKLLGARGKRHPCGNRQTVRFSDEYGGQCTFNRIKDSEHNNNDVGACAPFRRLHLCDYNLEKMGSTKIKDKNVLLAEVCMAAKYEGQSLLKQYEEHKNNYPHTNICTVLARSFADIGDIVRGKDLFLGHQQRKRKLEENLKQMFENIKKNNDKLDKISIEQVREYWWNANRDQVWEAITCHAAHSDEYFRKSTDGVTLYFDGRCGRELSSVPTYLDYVPQFLRWFDEWSEEFCRKRNITLKSAKEECQNDSKKLYCSLNGYNCTRLIPNKNYCSRDPICTPCSNKCIPYDLWLRNRRDEFNMQKGKYENEIKTYESDNDISNSNINTEYYKSFYKKFAKSDYKKVHDFLTLLNNGRYCKEGVDGKDAIDFNKTDDKDAFDRSEYCQPCPACVVECDGGKCEEKKNSDGTCIEAQIYTVVRDETPTPIKVLFSGDHQKDITKKLSSFCKNPESENNRDYQTWQCYYKSSDYNNCEMKGSLYKVEGDPNIIVSHECFHLWVQSLLIDTIKWETKLKKCINNTNVTNCYNKCNKNCECFENWVEQKKKEWENVNDVYKDQKQSLGIYYEKLENLFKSNFFQVMKALEGDEKGKWYQFKDDLKKKFEPSEKNTRTTDSQDAIKLILDHLKDNATTCKDNNSLEEDENCPKTKINPCIKRTRIPTRGASNNLVSVKHIAELMQRSARKQLEAGAGEINLKGDATKGKYTKKNGKAVALNDICSIDVQHSNSTYRSEKPCAGKNTGRFDIGTPWKTGTNVKMTEDQAYMPPRREHMCTSNLEYLETDQGPLKNSDGKFVNHSFLGDVLLAANHEAKKIKELYTKDNGLNDLKDKETVCRAMKYSFADLGDIIRGRDMWDNETGMKHAKKHLKDVFDNIRKSLKNKGNQKYNYDDKKLPPYKELREDWWEANRHQVWRAMKCAIKEATIDNCNGIPIEDYIPQRLRWMTEWAEWYCKMQSQEYKKLQDACTGCKKKVDSCTKGTPDCEQCDKQCKQYTEFITKWQPQWETMSYKYQTLYEEAERDATSGSVKKRTQLSKEDQRVVDFLKQLLLRNSAAARNRVIRAAGSSATGGTTAMTPNTPYSTAAGYIHHELGKTVGCNVQTKFCKHKIGSKASGTENKEYAFREKPYDHDDACACRPPKPTGGPGAGESPARSDADSRGPATVGAGEVEEDGDEVDSEEEEDEVEEEPPAEEVCEMVDTLLDESNGGKNGINGCNPKDQVQPYPGWDCKLSTFKDKEHGSCMPPRRIKLCVSGLTQTNNIINKEDIRTHFITCAAIETYFAWLRYKKINTEADKELKEGKIPDEFKRQMFYTFGDYRDIFFGTDISTHNHIPEVSSKVITILEKENGTKSEDKQKFNNVLLEDWWKEHGPEIWEGMLCALTNGLTDDEKKNEIKTKYSYDELNNAKKGDSSLEEFAQTSQFLRWMTEWGEDFCKKRKEQVETLQKACKFYECNINAEDTKTKCEKECKVYEQFIKQWKPQYEQQSKKFTTDKVQPEYAVDADVKKSTHAYQYLSKKLKKICQNGTTTDKCDYKCMENASRQPQTSACSQEQQQQNKSSTENNYPEAFDCPPKEIADKCNCPKPPEPKYCVDKTAYDIRKEREKKSDNSLKGNGTDIPLTDCTKVDTITFFNDNIGTTTINEKEMYKVFPPNSDSCDNKSSNRFNSEKQWLCNNINLKKKNICLPPRRQYMCLRKIERMITKDVDDKDKFFQVVMKAAKEEGIRILKNYKEQNKTDFSEICDDMKYSFADLGDIIRGKDLWNTDKNYKNIQDKIRYVFDYMHKKLNSDDQKRYKDLVNHYDLRSDWWDANRRDIWKAMTCAAPRNAYIYKTTENSETKIRSTDMYYYCGHKDDPPDNDYIPQKLRWMTEWSEYFCKELNRKLEQMKTNCDSCKLNDSNCRDSNDGNNCRKCQQNCQEYTKLVNQGKKQFILQDNQYKEIYKKISNNSDGKAYVGTHVVEFLKKVEKNKCSDLNSADKYLYKGSNCKNLTFTENDNEHRTRTYAFTEKPIEYKNKCTCEITNHPLDKCPTPQNRIICNNLKLINSYKKNYTINLKEWNNNLVPKISSDNYGVLVPPRRKHICLRNITANFLENKIYGKEKLRNAVLNAAYNEAYFLWTVYNKDSTTAFEAIKYSFADYGDIIKGTDIMESSLSDKIGNIFTNTKDTNARSKWWNEIKYQVWHAMLCGYRTANDKFVIDADTCKLPTEDEIPQFHRWLIEWAKQACKEYRIRKSAFEQFCHCSTAGGLSGLDLLKNHSCNYELTQYIGWNTMVKQYMDGFDIKFQKVKNASTNSSISENSAQEYIKGKIEGNECDFNDMENIYEKITNRKNKDFQEILGILCPNKKIDKDKSKEILDETSSKPKEEDTSHVQPPPLPPKPSTPEVEPLPSDEPFDPTILQTTIPFGVALALGSIAFLFLKKKTLSPVDLFSVINIPKGDYNIPTLKSSNRYIPYASDRYKGKTYIYMEGDSSGDEKYAFMSDTTDITSSESEYEELDINDIYVPRAPKYKTLIEVVLEPSKSNGNTLGDDIPHTNKFTDEEWNELKHDFISQYVQRESMGVPQYDVSTELPMNIGGNVLDDGINEKPFIMSIHDRNLYSGEEYSYNVNMVNSMDDIPINRDNNVYSGIDLINDTLSGNKHIDIYDEVLKRKENELFGTNHTKKNTSTNSVAKNTNSDPILNQINLFHTWLDRHRDMCEKLKNDNERLAKLKEEWENETHSGNTHPSDSNKTLNTDVSIQIHMDNPKPINQFTNMDTILEDLEKYNEPYYDVQDDIYYDVNDHDASTVDSNAVNVPSKVQIEMDVNTKLVKEKYPIADVWDI
Protein: Allyl alcohol dehydrogenase-like protein (Q8VZ93)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGILSWFTGSPKPSQSETSKPEMIQMPKSETPAPGMNGAIEVPRPDRATVFEFGSVAATGDRVTLAGYCPVSDDLEPCRWEILPADGKDAPQFRVVF
Protein: Chromogranin-A (CgA) (Pituitary secretory protein I) (SP-I) [Cleaved into: Vasostatin-1; Chromofungin; Chromostatin; Chromacin; Pancreastatin; WE-14; Catestatin; GE-25; Serpinin-RRG; Serpinin; p-Glu serpinin precursor] (P05059)
Organism: Bos taurus (Bovine)
Function: Strongly inhibits glucose induced insulin release from the pancreas.
Subcellular location: [Serpinin]: Secreted {ECO:0000269|PubMed:10781584}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P26339, ECO:0000269|PubMed:11584008}. Note=Pyroglutaminated serpinin localizes to secretory vesicle. {ECO:0000250|UniProtKB:P26339}.; SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P10354}. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle {ECO:0000250|UniProtKB:P10354}. Secreted {ECO:0000269|PubMed:11451958}. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. In pituitary gonadotropes, located in large secretory granules. {ECO:0000250|UniProtKB:P10354}.
Interaction partners:
- Secretogranin-1
- Carboxypeptidase E
- Secretogranin-2
- Leucine-rich repeat-containing G-protein coupled receptor 5
- Synaptophysin
- Somatostatin
- Secretogranin-3
- Pro-glucagon
- Peptide YY
- Neurogenin 3
Sequence:
MRSAAVLALLLCAGQVIALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSKECFETLRGDERILSILRHQNLLKELQDLALQGAKERTHQQKKHSSYEDELSEVLEKPNDQAEPKEVTEEVSSKDAAEKRDDFKEVEKSDEDSDGDRPQASPGLGPGPKVEEDNQAPGEEEEAPSNAHPLASLPSPKYPGPQAKEDSEGPSQGPASREKGLSAEQGRQTEREEEEEKWEEAEAREKAVPEEESPPTAAFKPPPSLGNKETQRAAPGWPEDGAGKMGAEEAKPPEGKGEWAHSRQEEEEMARAPQVLFRGGKSGEPEQEEQLSKEWEDAKRWSKMDQLAKELTAEKRLEGEEEEEEDPDRSMRLSFRARGYGFRGPGLQLRRGWRPNSREDSVEAGLPLQVRGYPEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHQLEELRRG
Protein: Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) [Cleaved into: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha-mannosidase E peptide] (O00754)
Organism: Homo sapiens (Human)
Function: Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. Cleaves all known types of alpha-mannosidic linkages.
Subcellular location: Lysosome.
Interaction partners:
- Alpha-mannosidase 2C1
- Beta-mannosidase
- Epididymis-specific alpha-mannosidase
- Alpha-N-acetylgalactosaminidase
- T-cell surface glycoprotein CD1e, membrane-associated
Sequence:
MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG