wanglab/gogpt-training-data huggingface dataset:
Protein: Retinal guanylyl cyclase 1 (RETGC-1) (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (Guanylate cyclase E) (GC-E) (Rod outer segment membrane guanylate cyclase) (ROS-GC) (P55203)
Organism: Bos taurus (Bovine)
Function: Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity).
Subcellular location: Photoreceptor outer segment membrane {ECO:0000269|PubMed:8102054}; Single-pass type I membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q02846}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Guanylyl cyclase-activating protein 1
- Guanylyl cyclase-activating protein 2
- Peripherin-2
- Neurocalcin-delta
- Opticin
- Neuropeptide Y receptor type 2
- Keratin 6B
- Somatoliberin
- Somatotropin
- Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
Sequence:
MTACTFLAGGLRDPGLCGPTRWAPSPPGLPPIPPRPRLRLRPPLLLLLLLPRSVLSAVFTVGVLGPWACDPIFARARPDLAARLAASRLNHAAALEGGPRFEVALLPEPCRTPGSLGAVSSALTRVSGLVGPVNPAACRPAELLAQEAGVALVPWGCPGTRAAGTTAPVVTPAADALYALLRAFRWAHVALVTAPQDLWVEAGHALSTALRARGLPVALVTSMEPSDLSGAREALRRVQDGPRVRAVIMVMHSVLLGGEEQRCLLEAAEELGLADGSLVFLPFDTLHYALSPGPDALAVLANSSQLRKAHDAVLTLTRHCPLGGSVRDSLRRAQEHRELPLDLNLQQVSPLFGTIYDSVFLLAGGVARARVAAGGGWVSGAAVARHIRDARVPGFCGALGGAEEPSFVLLDTDATGDQLFATYVLDPTQGFFHSAGTPVHFPKGGRGPGPDPSCWFDPDTICNGGVEPSVVFIGFLLVVGMGLAGAFLAHYCRHRLLHIQMVSGPNKIILTLDDITFLHPHGGNSRKVAQGSRTSLAARSISDVRSIHSQLPDYTNIGLYEGDWVWLKKFPGDRHIAIRPATKMAFSKIRELRHENVALYLGLFLAGGAGGPAAPGEGVLAVVSEHCARGSLQDLLAQRDIKLDWMFKSSLLLDLIKGIRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPVLERRGTLAGDVFSLGIIMQEVVCRSAPYAMLELTPEEVVKRVQSPPPLCRPSVSIDQAPMECIQLMKQCWAEQPELRPSMDRTFELFKSINKGRKMNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQMLPPSVAEALKMGTPVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGHRHAAEIANMALDILSAVGTFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASAMESTGLPYRIHVNRSTVQILSALNEGFLTEVRGRTELKGKGAEETYWLVGRRGFNKPIPKPPDLQPGASNHGISLHEIPPDRRQKLEKARPGQFSGK
Protein: ADP-ribosylating toxin CARDS (EC 2.4.2.-) (ADP-ribosyltransferase CARDS) (Community-Acquired Respiratory Distress Syndrome Toxin) (CARDX TX) (P75409)
Organism: Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
Function: The main virulence factor for this bacteria, a mono-ADP-ribosylating toxin (mART), that transfers the ADP-ribosyl group from NAD(+) to multiple target proteins in vitro. Also elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells as well as in mice and baboons. Treatment of mice or baboons with CARDS elicits a response that is consistent with human M.pneumoniae infections and mouse models of both infection and intoxication, suggesting that CARDS toxin is sufficient to cause prolonged inflammatory responses and airway dysfunction. Treatment of baboons with CARDS induces a number of cytokines; G-CSF (40 fold), IL-1Ra (10 fold), IL-6 and IL-8 (333 and 100 fold, respectively), MIP-1a (5 fold), and RANTES (9 fold). Treatment of mice gives a similar response. Binds phosphatidyl choline, dipalmitoylphosphatidylcholine (DPPC) and sphingomyelin via domains D2 plus D3.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16617115, ECO:0000269|PubMed:20199607}. Cytoplasm {ECO:0000269|PubMed:16617115, ECO:0000269|PubMed:20199607}. Cell surface {ECO:0000269|PubMed:15845487, ECO:0000269|PubMed:20199607}. Cell projection, attachment organelle {ECO:0000269|PubMed:20199607}. Host cytoplasm, host cytosol {ECO:0000269|PubMed:25538194}. Host endoplasmic reticulum {ECO:0000269|PubMed:29362229, ECO:0000269|PubMed:34078958}. Note=In bacteria most protein is cytoplasmic, 7-10% is on cell surface, including in the tip (attachment) organelle (PubMed:20199607). In host cells is found in the cytosol and in a punctate pattern in the perinuclear region in the host ER (PubMed:25538194, PubMed:29362229, PubMed:34078958). In host cells, an isolated C-terminal fragment (residues 273-591) is detected in a larger punctate pattern (PubMed:34078958). In 10% of host cells colocalizes with the speck NLRP3 inflammasome complex (purified protein incubated with mouse macrophages) (PubMed:25538194). {ECO:0000269|PubMed:20199607, ECO:0000269|PubMed:25538194, ECO:0000269|PubMed:29362229, ECO:0000269|PubMed:34078958}.
Interaction partners:
- Uncharacterized protein MG337 homolog
- Uncharacterized protein MPN_371
- Uncharacterized lipoprotein MG186 homolog
Sequence:
MPNPVRFVYRVDLRSPEEIFEHGFSTLGDVRNFFEHILSTNFGRSYFISTSETPTAAIRFFGSWLREYVPEHPRRAYLYEIRADQHFYNARATGENLLDLMRQRQVVFDSGDREMAQMGIRALRTSFAYQREWFTDGPIAAANVRSAWLVDAVPVEPGHAHHPAGRVVETTRINEPEMHNPHYQELQTQANDQPWLPTPGIATPVHLSIPQAASVADVSEGTSASLSFACPDWSPPSSNGENPLDKCIAEKIDNYNLQSLPQYASSVKELEDTPVYLRGIKTQKTFMLQADPQNNNVFLVEVNPKQKSSFPQTIFFWDVYQRICLKDLTGAQISLSLTAFTTQYAGQLKVHLSVSAVNAVNQKWKMTPQDIAITQFRVSSELLGQTENGLFWNTKSGGSQHDLYVCPLKNPPSDLEELQIIVDECTTHAQFVTMRAASTFFVDVQLGWYWRGYYYTPQLSGWSYQMKTPDGQIFYDLKTSKIFFVQDNQNVFFLHNKLNKQTGYSWDWVEWLKHDMNEDKDENFKWYFSRDDLTIPSVEGLNFRHIRCYADNQQLKVIISGSRWGGWYSTYDKVESNVEDKILVKDGFDRF
Protein: UDP-glucose:glycoprotein glucosyltransferase, putative (EC 2.4.1.-) (Q582S2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
- alpha-1,2-Mannosidase
- Calreticulin
- Calreticulin
- Sulfhydryl oxidase
- Derlin
- Derlin
- Endoplasmic reticulum oxidoreductin, putative
Sequence:
MSCCTLRSNEIRQLIVFIFVASIHCHVLTVEGKGVYVKVVAPWTETPLLQEGCEAVASLTVPVGTQTHDDAPSGFYKCLEDVWLRAEATNRSGGARTMTQKEQYDVLMDIMQSNKHPPHHVAFLTTKLAVRMHSPTVEAHRQLAGRAINRTGGCAAEGRPFALIGNKAFCDEHKLAKELELKGPSGSDATGCNADRETELNADNAMGVIANLDHVHPHLNGPNLVIMYGIVGEGQTMRLLQAVKRHKQTTKLVFRHLPVSGNQWNDMLAVQGYGVSVDIKSTEYRAVDDRIAGESTANLQHKLGRRDVLGAMGSGEEHLLGGFNISLLQKRYPDQSLQLSHFEDAVGKNIEQGVKVDLHSWEKAHIGIAAAQYVMDPSREPLHALLDVLTNFPNYASLLSRMSFVAAARKDPKFVRELDAIGRSMYHSSSHVFLNGCAVTTENINLFYMMEKIEEYERLLDTLSTILVSRSELHSSNDATRNGNTDVTDVVNGLARIQFQGESLSGGSGDTTARVWLPQDAVTWFNDVENNAYLYRLPTTLRSMLRNGAAAPTLPRRNVLHVVCIADPTTYEGMGTIFEVARRAQQPIRFGVVFVDKHWSPEVTLVGKKFDKVAVSDSSKATLLVAATVWELMQGEADPAAVSDFLMAMTREMMAKQTITELSVKMITQSVLMQARKRAVDDVVLDPAFITHYEKTQKMVRTLGFSKFPVVLLNGRVHTDISIVLQHGIWEEFAHLQKLVEMGALSDDDDNLYESVLELSGARTRYVAALFENKTFADWSHNSVLSFLHKYPFIYPSTSGMNEVSLVSGVLTLHVPVTAQSLQATLNAVRSLLLCKGADETCGRTRLTFAVCGTSLKTNSRTVVDDLHLLLQHCGVADKSECLNLLQEFLLSTFEHSHPGWQLDDPKKYEHVLKGVKFSDQLQALFRASAEGSTRDQAGKLNQLFLLASEFCREMTGSVSAVHEIAPGSVHYYVNGRLFVYDNFTEEDFEVATLEGGHTPKKVWNVLEEATFVGMDPGLEIPGSDQNFYASRIAAVVAALRRDAANNDRREEQKTRLPVSPGPLSFVVGATEKRVPRHRLTVVVDPVARASQQLVSLCNYISQLSIGAVCTVYLNPSLTVGNTIRNYYKFVGELQLRFDAEGRVVAPKAVFSHLPDKHLLTLGIEEAEYWTVFPMEAEYDLDNIILSRLPPSSKYLYATYRINSILISGSAEDDSTGGPSSGLPLQIRSSLYNHTSGSYTNTTRDTIVMTIKGYFQLQSTPGLWYLGVQPGAIARAFYISHHNDDPVLDVAVGSVGRHFNYTAGQSIPVVVSSFTGSFIRLGISRTAGFEEASIESIAAAAVEASNAEWPPKGPRSERPKFPTLNIFTVASGHLYERFLRIMMHTVMRTSSDVHGANTTRIKFWLIENFLSPQFKELVPLLAEHYGFDVGFVTYRWPWWLNKQTEKQRTIWAYKILFLDVLFPLNVDRVIFVDADQIVQADLHELYNMNIGAAAMAYTPFCREYPNDATTNFRFWDQGFWLSHLRGKPYHISALYLVNVQRLRAALGGDKYRATYARLSEDPGSLANLDQDLPNFMQDEMPIFSLPEEWLWCETWCAGESKARAKTIDLCNNPLTKIPKLENVRRIVDGWDEMDRELEDLSKQLLEKRNAELRDGAEKKKGQGKLMDPMDSSGMM
Protein: ATP-binding cassette sub-family B member 5 (ABCB5 P-gp) (P-glycoprotein ABCB5) (EC 7.6.2.2) (Q2M3G0)
Organism: Homo sapiens (Human)
Function: Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:12960149}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12960149}.
Interaction partners:
- ATP-sensitive inward rectifier potassium channel 11
- Prominin-1
Sequence:
MENSERAEEMQENYQRNGTAEEQPKLRKEAVGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISGCLVQTNTTNYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYIQISLWIITAARQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYGLAFWYGTSLILNGEPGYTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFSTAGYKPESIEGTVEFKNVSFNYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTDEEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAKRGLYYSLVMSQDIKKADEQMESMTYSTERKTNSLPLHSVKSIKSDFIDKAEESTQSKEISLPEVSLLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIITMFGNNDKTTLKHDAEIYSMIFVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILSIAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGKKPDTCEGNLEFREVSFFYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRLSAIQNADLIVVLHNGKIKEQGTHQELLRNRDIYFKLVNAQSVQ
Protein: Catechol 1,2-dioxygenase (EC 1.13.11.1) (1,2-CTD) (P07773)
Organism: Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Interaction partners:
- Muconate cycloisomerase 1
- 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
- Muconolactone Delta-isomerase
- Benzoate 1,2-dioxygenase electron transfer component
- Benzoate 1,2-dioxygenase subunit beta
- Benzoate 1,2-dioxygenase subunit alpha
- Anthranilate 1,2-dioxygenase electron transfer component
- Uncharacterized protein ACIAD1444
- HTH-type transcriptional regulator BenM
- Uncharacterized protein ACIAD1443
Sequence:
MEVKIFNTQDVQDFLRVASGLEQEGGNPRVKQIIHRVLSDLYKAIEDLNITSDEYWAGVAYLNQLGANQEAGLLSPGLGFDHYLDMRMDAEDAALGIENATPRTIEGPLYVAGAPESVGYARMDDGSDPNGHTLILHGTIFDADGKPLPNAKVEIWHANTKGFYSHFDPTGEQQAFNMRRSIITDENGQYRVRTILPAGYGCPPEGPTQQLLNQLGRHGNRPAHIHYFVSADGHRKLTTQINVAGDPYTYDDFAYATREGLVVDAVEHTDPEAIKANDVEGPFAEMVFDLKLTRLVDGVDNQVVDRPRLAV
Protein: Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Protein lactyltransferase) (EC 6.-.-.-) (P00957)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the attachment of L-alanine to tRNA(Ala) in a two-step reaction: L-alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). AlaRS also incorrectly activates the sterically smaller amino acid glycine as well as the sterically larger amino acid L-serine; generates 2-fold more mischarged Gly than Ser. These mischarged amino acids occur because the of inherent physicochemical limitations on discrimination between closely related amino acids (Ala, Gly and Ser) in the charging step.
Subcellular location: Cytoplasm.
Interaction partners:
- Valine--tRNA ligase
- Threonine--tRNA ligase
- Methionine--tRNA ligase
- Leucine--tRNA ligase
- Isoleucine--tRNA ligase
- Serine--tRNA ligase
- Aspartate--tRNA ligase
- Histidine--tRNA ligase
- Cysteine--tRNA ligase
- Glutamine--tRNA ligase
Sequence:
MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNTQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
Protein: Ras-related protein Rab-43 (Q8CG50)
Organism: Mus musculus (Mouse)
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium.
Subcellular location: Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:Q86YS6}. Cytoplasmic vesicle, phagosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus {ECO:0000250|UniProtKB:Q86YS6}. Golgi apparatus, trans-Golgi network membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q86YS6}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. {ECO:0000250|UniProtKB:Q86YS6}.
Interaction partners:
- USP6 N-terminal-like protein
- Pre-mRNA-splicing factor ISY1 homolog
Sequence:
MAGPGPGDQDEHYDFLFKLVLVGDASVGKTCVVQRFKTGAFSARQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQERFRTITQSYYRSANGAILAYDISKRSTFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLADFREVPLAEAQSLAEHYDILCAIETSAKDSSNVEEAFTRVATELIMRHGGPMFSEKNTDHIQLDSKDIAESWGCGC
Protein: Probable phosphatase C1620.13 (EC 3.1.3.-) (O94420)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Triosephosphate isomerase
- Phosphoglycerate kinase
Sequence:
MPLNVTVEEETLQIVEEEPQQEITNTILEEDFNLLDNSFQTDISSTSSQNDSKFTCLLVRHAESEHNVRGIRAGARIDSELTVHGYNQAKKLAKSIRNLDIVCVYSSPQKRAKRTAEEITKVANCPLYISDFLMEKDLGSLEGTSFRYTANYRPREPPMKVTNLESRDSLLTRARGFTDILFNEAIGFEGESGKTIVVVSHGIFLPFLLRAILARARTPLPSMIIPWNNASYCLITIDLGGNSIVKMNCNSHLRGIKRTRKLGSSTYDSKQKPITEFCSKLN
Protein: SD01527p (Q8T3L2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQIKEFRVTLPLTVEEYQVAQLFSVAEASKENTGGGEGIEVLKNEPFEDFPLLGGKYNSGQYTYKIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPKFMKDAFKIIIDTLHVGDAGDSENVHELTPDKLKVREVVHIDIANDPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKKHVNPVMTCYKLVTCEFKWFGLQTRVENFIQKSERRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKEELDKARQVGEVWGMRADAD
Protein: Uncharacterized protein C622.14 (O94601)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: GTPase-activating protein for the ADP ribosylation factor family.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- ADP-ribosylation factor GTPase-activating protein glo3
- ADP-ribosylation factor 1
- Probable electron transfer flavoprotein subunit beta
- Uncharacterized protein C211.03
Sequence:
MSYKLDQLTRLPENKKCFDCDAPNPQWASCNLGIFICLDCSGQHRGLGVEKSFVRSITMDNWSERQVKMMEVGGNSNAKTFLSTDPMFSAAGSIREKYNTDIAEDLRQKIRAEVDGVEWVKVDRPKSVSSHASVTSSSTVPTIPSVSKEANDKYFAKLGSINSQRPDDLPPSQGGRYQGFGSSNSVNPNSSARNNGGSFLDQLSSNPVSALSHGWNMFSRSVSQQIQDVNKSYIQPGITKVQDPETRKDYMNAINNFSSNVQEGAKQSFTQLKSFLDENVYSENPQNTRGTYDAEIDSPYSALAASPPPEDYSKKNFDKHD
Protein: Probable glucan endo-1,3-beta-glucosidase At4g16260 (EC 3.2.1.39) (Q8VZJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in plant defense against cyst nematode pathogens.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Actin-related protein 4
Sequence:
MTTLFLLIALFITTILNPTSGESVGVCYGMMGNNLPSQSDTIALFRQNNIRRVRLYDPNQAALNALRNTGIEVIIGVPNTDLRSLTNPSSARSWLQNNVLNYYPAVSFKYIAVGNEVSPSNGGDVVLPAMRNVYDALRGANLQDRIKVSTAIDMTLIGNSFPPSSGEFRGDVRWYIDPVIGFLTSTNSALLANIYPYFSYVDNPRDISLSYALFTSPSVVVWDGSRGYQNLFDALLDVVYSAVERSGGGSLPVVVSESGWPSNGGNAASFDNARAFYTNLASRVRENRGTPKRPGRGVETYLFAMFDENQKSPEIEKNFGLFFPNKQPKFPITFSAARDGTAVE
Protein: Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) (P98070)
Organism: Xenopus laevis (African clawed frog)
Function: Metalloprotease involved in pattern formation in gastrula and later differentiation of developing organs. Able to cleave chordin (chrd), suggesting that it may act in dorsoventral patterning during early development by regulating the chordin (chrd) activity.
Subcellular location: Golgi apparatus, trans-Golgi network {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
Sequence:
MDYSYDLEEVVEETIDYKDPCKAAAFWGDIALDEEDLANFKIDRIVDLTKHTIHTVSGAATNISRPEKGRRTRKERRRSREKRASTSRPERVWPDGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEYNFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYDVNGVRPPIGQRTRLSSGDVAQARKLYKCPACGETLQDSQGNFSSPGFPNGYSAYMHCVWRLSVTPGEKIILNFTSLDLYRSRLCWYDYIEVRDGFWKKAPLRGRFCGDKIPESIISTESRLWIEFRSSSNWVGKGFQAVYEALCGGEVKKDSGHIQSPNYPDDYRPNKACVWKLSVSEGFHVGISFQSFEIERHDSCAYDYLEIRDGSSETSPLVGRFCGYDKPDDIKSSTNQLWIKFVSDGSINKAGFSLNYFKEVDECSRPNNGGCEQRCVNTLGSYKCACDPGYELGQDKKSCEAACGGFLTKLNGSINSPGWPKEYPPNKNCIWQLVAPTQYRISLKFDQFETEGNDVCKYDFVEVRSGLTSDSKLHGKFCGSELPAVITSQYNNMRIEFKSDNTVSKKGFQANFFSEKKNNIQKLQQLNEVNRGQQNQAPKRVRPRMRLRTVKKTRPP
Protein: Barrier-to-autointegration factor-like protein (BAF-L) (Barrier-to-autointegration factor 2) (Q9H503)
Organism: Homo sapiens (Human)
Function: May play a role in BANF1 regulation and influence tissue-specific roles of BANF1.
Subcellular location: Nucleus. Cytoplasm.
Interaction partners:
- Emerin
- Inner nuclear membrane protein Man1
- LEM domain-containing protein 2
- Histone H3.2
- Histone H3.1
- Histone H3.3
- Histone H3.1t
- Histone H3-7
- Histone H3.3C
- Prelamin-A/C
Sequence:
MDNMSPRLRAFLSEPIGEKDVCWVDGISHELAINLVTKGINKAYILLGQFLLMHKNEAEFQRWLICCFGATECEAQQTSHCLKEWCACFL
Protein: Tyrosine-protein phosphatase yvh1 (PTPase yvh1) (EC 3.1.3.48) (O13632)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May be directly involved in signal transduction and/or cell cycle regulation. It is necessary for maintaining growth rate or spore germination. Could show both activity toward tyrosine-protein phosphate as well as with serine-protein phosphate (By similarity).
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- 60S ribosomal export protein nmd3
- Probable metalloprotease arx1
- Ribosome assembly factor mrt4
- Large subunit GTPase 1
- Ribosome biogenesis protein rlp24
- Eukaryotic translation initiation factor 6
- Cytoplasmic 60S subunit biogenesis factor SPCC550.15c
- Ribosome biogenesis protein nsa2
- Ribosome production factor 2 homolog
- Curved DNA-binding protein
Sequence:
MSNKSAWQPQFDEIHSSVQEAEGFLQSSNDVQKAIDEVHYPDSLNDLSEISKNLYISSWKTASELVSTSDKGIDYTLSAMSINPNLSVPEQQHLWLQIEDSSSQNILQYFEKSNKFIAFALSKNAKVLVHCFAGISRSVTLVAAYLMKENNWNTEEALSHINERRSGISPNANFLRQLRVYFECNYQLDRSLRPYRQWLFRRYGDFAVLNTRVPSEVAYAETVRARAGQLELRCKKCRFVLASSDYLVSHEPKDENNYSHTRCTHYFLEPIRWMQPELELGNLEGRFDCPKCNSKIGSYKWQGLQCSCLQWVCPALSILQSRVDAVRKLG
Protein: Hyperkinetic, isoform K (M9PE66)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSMALCNLNGDGSAAQSTSQSQSQSPAATAAAAPLLPHSHSHTLQPESTPLLLGHEQSGSAAPEGSGGGDVTDGAVTSIEMPTVVADDAGVPPLPLPLPQSTPQPLLMALPANLNFITGPTTQQLMIGNGAMGVIPSTNDSNNNNNNNNNVDNTSDESNPVTIYRCRAPIASLDCMEEFSGRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAHSETEIGKILQRAGWKRTAYVITTKVYWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCPMEVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMISTLALR
Protein: Bardet-Biedl syndrome 8 protein (Q382T6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- PTHB1 N-terminal domain-containing protein
- FG-GAP repeat protein, putative
- FG-GAP repeat protein, putative
- BBSome complex member BBS5 PH domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Anaphase-promoting complex subunit 5
- Uncharacterized protein
- Uncharacterized protein
- Dynein axonemal assembly factor 4
Sequence:
MGVRAITLYVLFLSNIFHYLHSLPMAEMTEAPSTGHANPIEVDSEAPPGIDPMYYALSLLRRRRLEECVAISSRSLATLVSSGNSAEKKVCGQSPNDGHIERTVTRFWSIQMKALAQQNWFEEIDVDDDGVNDVLLDGEQTVPSNATAVGTSLGGGQPPAAANPGKPPSRMSCGKGTMRPLSSRCGFARPGTHSARLGSSSMSPVTARLARVGTASLQSVPGGTHLDLQKLDVVKYVQDKPIVAKLLCDYLLHVAHRPRMVLELCNYILSQEEQRNWWWLSRLGQAHYRLGQLREAEQQFKSALALQENVMDVLRLAKVFVRMDQPLKALEVLSGASSKNVTDHHLRIAMARLYEELQDKEKSCDMYRRVLQLDSTNVEAIACIAAHHFYENQQPEVALRLYRRLLQMGVQTTELWNNLGLCCFYSSQYDIALSCLQRAAAVAPDDESLSDVWFNIGHVGIATGDLSLAERAFRVAVAANPQRAEALNNLAVLQLRAGNVEAAYSDITMALAVQPLQLESLYNAALIAYSSGFFEQAYAQLQRALDVCPDHPESVGLQAEIRKILAAP
Protein: Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (tRNA-t(6)A37 methylthiotransferase) (Q9C7H2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- NifU-like protein 3, chloroplastic
- Lipoyl synthase, chloroplastic
- Lipoyl synthase, mitochondrial
- NifU-like protein 2, chloroplastic
- Ribosomal RNA-processing protein 40
- Ribosomal RNA-processing protein 40
- NifU-like protein 4, mitochondrial
- MMS19 nucleotide excision repair protein homolog
- Amidophosphoribosyltransferase 1, chloroplastic
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
Sequence:
MEDIEDLLAGGVGGAPPGFRLPLNAVGINPKTNKSKRISSKPDQITASNRDSLAPPSMKIPGTQTIYIKTFGCSHNQSDSEYMAGQLSAFGYALTEVPEEADLWLINTCTVKSPSQSAMSTLITRGRSGKKPLVIAGCVPQGSRDLKELEGVSVVGVQQIDRVVEIVEETLKGHEVRLLTRKTLPALDLPKVRRNNFIEILPINVGCLGACTYCKTKHARGHLGSYTVDSLVERVRTVISEGVKEIWLSSEDTGAYGRDIGVNLPILLNAIVKELPSDQSTMLRIGMTNPPFILEHLKEIAAVLRHPCVYTFLHVPVQSGSDSVLTAMNREYTASEFRTVVDTLTELVPGMQIATDIICGFPGETDEDFSQTVELIKDYKFPQVHISQFYPRPGTPAAKMKKVQSKIVKQRSRELTSVFEAFAPYTGMECREERIWITEVATDGIHLVGHTKGYVQVLVTGPESMLGTSAMARITSVGRWSVFGEVIETFSSANRETKSREETKLPCSSNVSTCETCTCSAESCGEERSGEACNISGNISGQDDNKGKSKKEEKEVQEVVVPGSSVANWGFIDKALVCGVFVSSVTILVLLISIACRVLLR
Protein: HCG2025883, isoform CRA_b (POLR2C protein) (cDNA FLJ76636, highly similar to Homo sapiens polymerase (RNA) II (DNA directed) polypeptide C, 33kDa (POLR2C), transcript variant alpha, mRNA) (Q6FGR6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN