wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger CCCH domain-containing protein 14 (Nuclear protein UKp83/UKp68) (Q7TMD5)
Organism: Rattus norvegicus (Rat)
Function: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:21734151}. Note=Colocalizes with poly(A) RNA in nuclear speckles. {ECO:0000269|PubMed:21734151}.
Interaction partners:
- Aly/REF export factor
- Nuclear cap-binding protein subunit 2
- Transportin-1
- Transportin 2
- Musashi RNA-binding protein 2
- RNA-binding protein Musashi homolog 1
- DAZ associated protein 1, isoform CRA_a.
- Polyadenylate-binding protein 2
Sequence:
MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSPDTSIFDSNVPSNKSSFSRGDERRHEAAIPPLAVSSSRPEKRDSRVSTSSQEHKSTNVRHSYDDGASTRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENSLSQKKPTVTLTYGSSRPSIEIYRPPASRNADTGTHLNRPQLQQQQSSTHTAKQLDGQSSQVYEAGRLCEPEVLGSVEDTYSPFFRNNLDKMNIEEENFRKRKLPVVSSVVKVKRFSHDGEEEEEDEDYGTRVGSLSSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYPAVPQKQTLPVAPRTRTSQEEVLAEMVQGQNRAPRISPPVKEEEAKGDNAEKIEGTQQRQLLSRLQIDPVTVDTMELSQDYYDMESMVHADTRSFILKKPKLSEEIVVTPNQDSGMKTADALRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEEMCFEGMKPVNQTSASNKGLRGLLHPQQLHLLSRQLEDPDGSFSNAEMTDLSVAQKPEKLLERCKYWPACKNGDECVYHHPISPCKAFPNCKFAEKCLFVHPNCKYDAKCTKADCPFTHMSRRGPVLTPKPAVSSPAPSSNGQFCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTITVPPRHALKWIRPQTSE
Protein: Sodium/glucose cotransporter 1 (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1) (Q9I8D9)
Organism: Gallus gallus (Chicken)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004424}.
Interaction partners:
Sequence:
VECLGGYEWNALIFVVVLGWVFVPIYIKAGVVTMPEYLRKRFGGKRIQVYLSILSLILYIFTKISADIFSGAVFIQLAMGLNLYLAIIILLAITALYTITGGLAAVIYTDTLQTFIMVVGSFILMGFAFREVGGYDAFMEKYMNAVPSNITYGNSTIDSKCYTPRADSFHIFRDAVTGDLPWPGLTIGGSILTLWYWCTDQVIVQRCLSGKNMSHVKAGCVMCGYLKLLPMFIIVMPGMISRILYTDVVACAVPEICQQACGTTVGCTNIAYPKMVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYTKVRKQP
Protein: Brevinin-1E (P86149)
Organism: Pelophylax ridibundus (Marsh frog) (Rana ridibunda)
Function: Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.
Subcellular location: Secreted {ECO:0000269|PubMed:18280749, ECO:0000269|PubMed:18855342}.
Interaction partners:
Sequence:
FLPLLAGLAANFLPKIFCKITRKC
Protein: Synaptobrevin (Synaptic vesicle-associated integral membrane protein) (VAMP-1) (P13701)
Organism: Tetronarce californica (Pacific electric ray) (Torpedo californica)
Function: This protein may play a role in packaging, transport or release of neurotransmitters.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Synapse, synaptosome. Note=Neuronal synaptic vesicles.
Interaction partners:
Sequence:
MSAPPSGPAPDAQGGAPGQPTGPPGAPPNTTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGGIGAIIVIVIIIYFFT
Protein: Cyclohexadienyl dehydrogenase (Arogenate dehydrogenase) (ADH) (EC 1.3.1.43) (Prephenate dehydrogenase) (PDH) (EC 1.3.1.12) (Q04983)
Organism: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Function: Can function as either prephenate dehydrogenase or as arogenate dehydrogenase in the biosynthesis of L-tyrosine. Catalyzes two analogous reactions: converts prephenate to 4-hydroxyphenylpyruvate and transforms L-arogenate to L-tyrosine. Is not able to utilize NADP(+) instead of NAD(+) as cosubstrate.
Interaction partners:
- Histidinol-phosphate aminotransferase
- 3-phosphoshikimate 1-carboxyvinyltransferase
- prephenate dehydratase
- chorismate mutase
- Aminotransferase class I and II
- Aminotransferase class I and II
- Aminotransferase class I and II
- Aminotransferase
- Aromatic-amino-acid transaminase
- Chorismate synthase
Sequence:
MTVFKHIAIIGLGLIGSSAARATKAYCPDVTVSLYDKSEFVRDRARALNLGDNVTDDIQDAVREADLVLLCVPVRAMGIVAAAMAPALKKDVIICDTGSVKVSVIKTLQDNLPNHIIVPSHPLAGTENNGPDAGFAELFQDHPVILTPDAHTPAQAIAYIADYWEEIGGRINLMSAEHHDHVLALTSHLPHVIAYQLIGMVSGYEKKSRTPIMRYSAGSFRDATRVAASEPRLWQDIMLENAPALLPVLDHFIADLKKLRTAIASQDGDYLLEHFKESQKARLALKTDHDIRP
Protein: Forkhead box protein pes-1 (Pattern expression site 1) (G5EGC9)
Organism: Caenorhabditis elegans
Function: Transcription factor (By similarity). Plays a role in embryogenesis and later development, perhaps acting redundantly with forkhead protein fkh-2.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089, ECO:0000269|PubMed:8162851}. Cytoplasm {ECO:0000269|PubMed:8162851}.
Interaction partners:
- Zinc finger protein lsy-27
- Putative forkhead-related transcription factor fkh-5
- Zinc finger protein ehn-3
- T-box transcription factor tbx-9
- C2H2-type domain-containing protein
- Putative T-box protein 36
- Homeobox ARX homolog alr-1
Sequence:
MTSSIKSDAPQFLLDLDNCSSLPPTPPKTASPGNSKMKGFNISDLCLDLDSSTSSSCSVSPASSFHTRSESVGQQQSGRNSPVSSSTESPTKRPKYSYNALIAMAIQSSPFKSLRVSEIYKYISSNFSYYKNQKPLQWQNSVRHNLSLHKEFRKVRTLDGKGSYWAMTADLGTDVYISNNCGKLRRQKSKVAKFPPMQQHFPIPQLPTQNIHQLCMQNPQILATLLQNMYLQNMQNLQNIPMVPGFPIIPVPINPTSFHFPKSS
Protein: Protein saf4 (O60141)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May be involved in mRNA splicing.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Pre-mRNA-splicing factor cwf2
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-splicing factor cwf14
- U2 small nuclear ribonucleoprotein A'
- Splicing regulator sde2
- Stress response protein bis1
- Small nuclear ribonucleoprotein F
Sequence:
MQGFNMGKYIPPEGPNAKRKFDKLRNVIRFEMPFPVWCNNCENIIQQGTRFNAVKKEIGSYYTTKIWSFSLKCHLCSNPIDVHTDPKNTEYIVASGGRRKIEPQDINERPAKAENDEKVPSDAIEALETQLTQQKSEKHNSSVINFIYEKNERLWSDPFVSSQRLRKQFRERKKIEKKQEAKDLSLKNRAALDIDILPPSSSDKDKALLLLDNELGKNKFIRKLDYRRTLMPSSRTFSTFAKFAETSFAKKDPFARKFVPSEKLRSEQRKFPTENLKGEKILEDNSVSLVNYEVSDDEG
Protein: U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A) (P09012)
Organism: Homo sapiens (Human)
Function: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
Subcellular location: Nucleus.
Interaction partners:
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein Sm D2
- U2 small nuclear ribonucleoprotein A'
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein Sm D3
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein-associated proteins B and B'
- U1 small nuclear ribonucleoprotein 70 kDa
- U1 small nuclear ribonucleoprotein C
- Small nuclear ribonucleoprotein F
Sequence:
MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK
Protein: Cellulose biosynthesis protein BcsG (P37659)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cellulose biosynthesis protein BcsF
- Cyclic di-GMP binding protein BcsE
- Cellulose synthase catalytic subunit
- Endoglucanase
- Cyclic di-GMP-binding protein
- Protein YhjR
Sequence:
MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHPLLNLVFAAFLLMPLPRYSLHRLRHWIALPIGFALFWHDTWLPGPESIMSQGSQVAGFSTDYLIDLVTRFINWQMIGAIFVLLVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFSLWPAGQPTTTVTTTGGNAAATVAATGGAPVVGDMPAQTAPPTTANLNAWLNNFYNAEAKRKSTFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATSYSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLKEVRENGGMQSELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNTLPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGDRMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIEQPSSFLAISDLVVRVLDGKIFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ
Protein: Aminopeptidase, putative (Q387N9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 60S ribosomal protein L4
- 60S ribosomal protein L5, putative
- 60S ribosomal export protein NMD3
- 60S ribosomal protein L35, putative
- Ribosome biogenesis protein NOP53
- 60S ribosomal protein L19, putative
- 60S ribosomal protein L2, putative
- Large ribosomal subunit protein uL5
- 60S ribosomal protein L18a
- 60S ribosomal protein L10, putative
Sequence:
MSRPEGEEGKIEEWEDVDEQAEEEEEDTTINNSDVVMRYKKAAVWCNETLQVLLDAIVPGAKVYDLCKLGDETIAKKLRTMFRGTEKGIAFPTCISLNNCVAHNCPSPGDDAASQVVQLGDVVHVDLGIHIDGYCAQVAHTVQVTENKELGSDEKAAKVITAAYKILNTAVRKMRPGTNVYEVTEVIEKAAAHYGVTPAEGVLSHMLKRYIVDSFRCIPQKKVAEHLVHDYTLEAGQVWTLDIVMSSGKGKLKERDLRPSVFKVALDSKYTMKMESARELQREIESKYGTFPFAFRNLETKKARLGLSEMVKHSAVVPYPVLYEKDGEVVGHFKVTLLVTAKKIEVVTGLKMQKAPELPPYTDELLLTTSKLPFSLEKKRKE
Protein: Mitochondrial carrier protein, putative (Q57VZ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSDVPWAQKPEENQSNIEKHTAGDAPTEFDGGTATAELGPHEHTNSLNRSYSDLDSMWFVTYAVILCWLRTAAQQPLNLALARKQTSSVANKMTTRQIIRLVYNTEGGLLGLTQGMAALALGCALSEAIYLWLFEYSRENIPLANKPTRDAVSGYIADALCRLVHLPLSIVALRQMTANCEGVQRGRAVKSGCMIHTFASMYREGGLRTIYAGYGTTLVIGCQWTAVWWAMYGVSKGYLYAAADGFLLDGREDPVTEPVFVSSSWLSWKRWLLARDDNVALNTVASVITSAVTAVIFNPYLVVRANLQVAPKARLWGVTCEVYRTRGILGFYGGLALNIGTCLIDGVLASTSYEYAKLWADRAHQSG
Protein: Uncharacterized protein (Q9VMK7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein
- Kazal-like domain-containing protein
- MIP13722p
- Mucin 4B, isoform B
- HDC17346
- MIP15303p
- Femcoat
Sequence:
MAKTMTFWFLVLALVTLNPTWPFWRTGAAEVTSASMFQFLDRHNGEGDHSWSHLLPTNFYSEMNQQYYRRFRRQAGRMDTFRSGKRQQYPFEYARYV
Protein: Clathrin interactor EPSIN 2 (EPSIN-related 2) (Q67YI9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly (By similarity). Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3)P). Plays an important role in protein trafficking.
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:17277094}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:17277094}. Note=Also localizes to a novel cellular compartment, the 'delta compartment', characterized by colocalization of EPSIN2 and DELTA-ADR.
Interaction partners:
- Clathrin heavy chain 2
- Clathrin heavy chain 1
- AP-2 complex subunit alpha-1
- Clathrin coat assembly protein AP180
- Vesicle transport v-SNARE 12
- AP-2 complex subunit alpha-2
- Putative clathrin assembly protein At2g25430
- Beta-adaptin-like protein B
- Calcium-binding EF hand family protein
- Putative clathrin assembly protein At2g01920
Sequence:
MKKVFGQTVRDLKREVNKKVLKVPGVEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMVVIWKRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVALVNDKERIAEVRQKAAANRDKYRSSAPGGMYKPSGGYGDKYDYGSRDEERSSYGREREYGYRDDDRNSRDGDRHSRDSEDRYGRDGNRDDDYRGRSRSVDNYGSRGRSSEREREDDGHSSSRGSGARADDNSQDGRGGLQRKFSEQNIGAPPSYEEAVSDSRSPVYSERDGGETPQVTAPGAASPPPPQVAAPEAASPPTGTNTANTTATFVNESPSQKVETFDEFDPRSAFSAGPPAYASTDGVTAPPTVTSMSAPTTSNSVEMDLLGSLADVFSSNALAIVPADSIYVETNGQANAGPAPSFSTSQPSTQSFDDPFGDSPFKAFTSTDTDSTPQQNFGASFQPPPPAFTSEVSHPDTAHNFGFGDSFSAVANPDPASQNVQPPSNSPGFPQEQFATSQSGIDILAGILPPSGPPVQSGPSIPTSQFPPSGNNMYEGFHSQPPVSTAPNLPGQTPFGQAVQPYNMVPHSQNMTGAMPFNSGGFMHQPGSQTPYSTPSGPAGQFMAHQGHGMPPSHGPQRTQSGPVTLQGNNNVMGDMFSQATPNSLTSSSSHPDLTPLTGAIEIVPPPQKKFEPKSSVWADTLSRGLVNFNISGSKTNPLADIGVDFEAINRREKRLEKQTNTPATSTINMGKAMGSGTGLGRSGATAMRPPPNPMTGSGMPMGGGMGVGSYGGMNQNQPMGMGMGAGMNQNQPMGMGMGPGMNMNMNMGGYGQGYPMQPQNPGMVPSPNMPGNNYNPMMGQGGYNPQQSYGGGYR
Protein: Helix-loop-helix protein 11 (P34474)
Organism: Caenorhabditis elegans
Function: Transcriptional regulator. Component of a feedback loop involving atfs-1, atgl-1 and hlh-11. Binds to the promoter of the atgl-1 lipase to negatively regulate the expression of atgl-1, and thereby promoting fat oxidation in response to mitochondrial stress and mitochondrial respiration in the intestine. In addition, functions with atfs-1 to maintain lifespan. May have a role in fertility and in positively regulating body size.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:33078707}.
Interaction partners:
- Protein mxl-3
- Helix-loop-helix protein 25
Sequence:
MVRSDSAEEDQIIIDDGFDLTEEDEEMMSSGTGALPVTIADWNSVTNARMAPPSIMSAASAFDLTASGMQNSLRSVLPTSTIGHAPMLANRSLSQPAPLSPTSLDPDRRSRMRRQIANCNERRRMQSINAGFLALRALLPRKEGEKLSKAAILQQTADMVHQLLGHKGEDIPDGGEPKKLKLEEDHHDADHQAQIAHLQTILETERAARKALESQVIQLRELLQMTTTSSQASSPVTPRSNGSGGFTLPSSYASSALPTPLRESPERKPSFQDTTSTPLSLLTLNGSPTSSESLASQRIFHPPPTLPSLETTVIRPTPLPPISVEISSPSLSTPSPLTAAPIIFSTAVPTQSSILFQTAAAAVTSAMSTGNSTPVALPHHLQGHNSAFVSTQPSLTLSQSMQTIVEAIRHLEGSHFIPTSPPPTSQTSLVR
Protein: Phosphodiesterase (EC 3.1.4.-) (Q9QXI7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MTAKNSPKEFTASESEVCIKTFKEQMRLELELPKLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFLYDLDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGINTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLEETDIDIATEDKSPIDT
Protein: receptor protein-tyrosine kinase (EC 2.7.10.1) (A0A0G2JY48)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Ephrin-B3
- Ephrin-B1
- Ephrin-A5
- Ephrin B2
- Ephexin-1
- Tyrosine-protein kinase
- Ras GTPase-activating protein 1
- Ephrin-A4
- Tyrosine-protein kinase.
- Ephrin-A1
Sequence:
QMTSTLGCPLLTPSSWLDSGPELAKDWETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDLATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRNGFYLAFQDYGGCMSLIAVRVFYRKCPRVIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAVNRVVALFNHLLCSQQELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEVASRGCPPSLPMAYCGSHLPGCLQVAPALCSCSRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFTNAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEV
Protein: Fidgetin-like protein 1 (EC 3.6.4.-) (Fidgetin homolog) (O16299)
Organism: Caenorhabditis elegans
Function: Has a role in spindle assembly which acts in the progression through mitosis during embryogenesis. Required for fertility.
Subcellular location: Nucleus {ECO:0000269|PubMed:17878235}.
Interaction partners:
- MutS protein homolog him-14
- Protein maternal effect lethal 26
- Meiotic recombination protein spo-11
- IST1 homolog
Sequence:
MYSPKRVKLNVTSGMRKRPETGENNDDLYPPTALARNGISPYFIGKPRRKIVVETPSDSAQQQPPFKSRSQQNGLDDELDGIIIDEDEDRTVDVSFSQKQDTRKLKSRPFLGEKSSFKLGEIPKPKEEKRREEPFTMRGFDFGSDDKVTKIRDKICDIVDPTNARRTDPNFIRQMHENTLKGIEVASNPHFKKTRAPTKNRAAIQNTLGTLYPSFTTAAGQDPQNSKFQVPLDRQSSSQSIGSLAGIPPARRAPDIPKRCSNPLIRKAMGMDTEGGGKDEKMSGLRAEPTLKHFDENIISLIESEIMSVNNEIGWADVAGLEGAKKALREIVVLPFKRPDVFTGIRAPPKGVLLFGPPGTGKTMIGRCVASQCKATFFNISASSLTSKWVGEGEKLVRALFSVARLKLPSVIFIDEIDSLLSSRSESEHESSRRIKTEFLVQLDGVNTAPDERLLVLGATNRPQELDEAARRRFQKRLYIALPEPESRTQIVQNLLVGTRHDITNHNLERIRELTDGYSGADMRQLCTEAAMGPIRDIGDDIETIDKDDIRAVTVMDFAEAARVVRPTVDDSQLDAYAAWDKKFGCLPPPSISR
Protein: Hemogen (R4GE89)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MEDPLEKEIPPTEIKDSDEGGIRRRLRDRDLLKKRKAEAEEKATNQWVYGAQSIKRVKKRTTTGTPGRKGRPRKEPIVIAEDLGLAQEVDPSPITIPVTEPELPTIAEIEPLQPVEPQQELVPEEAISEKPQEEFLIEDLGPDEEEDMPQKHLVIDTGDDEKPYNDVPEQSSIAIPMFAPAPDSSQPDNLSLTENLLF
Protein: Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1) (Q9DCB8)
Organism: Mus musculus (Mouse)
Function: Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q86U28}.
Interaction partners:
- Iron-sulfur cluster assembly 1 homolog, mitochondrial
- Iron-sulfur cluster assembly factor IBA57, mitochondrial
- Iron-sulfur cluster assembly enzyme ISCU
- NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
- Cysteine desulfurase
- Glutaredoxin-related protein 5, mitochondrial
- Ferredoxin-2, mitochondrial
- Iron-sulfur cluster assembly 1 homolog, mitochondrial
- BolA-like protein 1
- Lipoyl synthase, mitochondrial
Sequence:
MAASRALSLTAEAVRAVIPRRSGRLLAVFPRLLTRWETTSSIPEAGEGQIRLTDSCVQRLLEITEGSEFLRLQVEGGGCSGFQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSCGSSFSVKV
Protein: Protein ripply3 (Down syndrome critical region protein 6 homolog) (Q2WG78)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Probable transcriptional regulator involved in developmental processes.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q2WG80}.
Interaction partners:
Sequence:
MLPVCVDADQALRCSVLWRPWSLSPTEARGHKTLAGGVRSARPSGGVFHHPVRLFLPRSRMQEYLSRLGSSVLASFPVQATLHFYNDEDSSSEEEEDEEHANTRCRLWRP
Protein: Stage V sporulation protein AD (P40869)
Organism: Bacillus subtilis (strain 168)
Interaction partners:
- Stage V sporulation protein AC
- Stage V sporulation protein AEB
- Stage V sporulation protein AF
- Stage V sporulation protein AE
- Stage V sporulation protein AB
- Stage V sporulation protein AA
- Germination protease
- Spore germination protein KA
- Spore germination protein A1
- Spore cortex-lytic enzyme
Sequence:
MKLTGKQTWVFEHPIFVNSAGTAAGPKEKDGPLGSLFDKTYDEMHCNQKSWEMAERQLMEDAVNVALQKNNLTKDDIDLLLAGDLLNQNVTANYVARHLKIPFLCMFGACSTSMETVAVASALVDGGFAKRALAATSSHNATAERQFRYPTEYGGQKPDTATSTVTGSGAVVISQTPGDIQITSATVGKVSDLGITDPFDMGSAMAPAAADTIKQHFKDLNRTADDYDLILTGDLSGVGSPIVKDILKEDGYPVGTKHDDCGLLIYTPDQQVFAGGSGCACSAVVTYSHIFKQLREGKLNRVFVVATGALLSPTMIQQKETIPTIAHGVVFERAGGAS
Protein: Spectrin beta chain, erythrocytic (Beta-I spectrin) (P11277)
Organism: Homo sapiens (Human)
Function: Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.
Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Interaction partners:
- Ankyrin-1
- Spectrin alpha chain, erythrocytic 1
- Spectrin alpha chain, non-erythrocytic 1
- Protein 4.1
- Ankyrin-2
- Ankyrin-3
- Band 4.1-like protein 2
- Tropomyosin alpha-3 chain
- Spectrin beta chain, non-erythrocytic 4
- Spectrin beta chain, non-erythrocytic 5
Sequence:
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVRALEDLAQELEKENYHDQKRITARKDNILRLWSYLQELLQSRRQRLETTLALQKLFQDMLHSIDWMDEIKAHLLSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLKFTEGKGYQPCDPQVIQDRISHLEQCFEELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLEQIFQEAHGMVARKQFGHPQIEARIKEVSAQWDQLKDLAAFCKKNLQDAENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKDFLEELEESRGVMEHLEQQAQGFPEEFRDSPDVTHRLQALRELYQQVVAQADLRQQRLQEALDLYTVFGETDACELWMGEKEKWLAEMEMPDTLEDLEVVQHRFDILDQEMKTLMTQIDGVNLAANSLVESGHPRSREVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHNYCVDCEETSKWITDKTKVVESTKDLGRDLAGIIAIQRKLSGLERDVAAIQARVDALERESQQLMDSHPEQKEDIGQRQKHLEELWQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQDSYQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWNALGRMWESRSHTLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRDKVLSPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQNCQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGDADLSIEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEKPTTLELKERQIAERPAEETGPQEEEGETAGEAPVSHHAATERTSPVSLWSRLSSSWESLQPEPSHPY
Protein: (R,R)-butanediol dehydrogenase (EC 1.1.1.4) (P39714)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: NAD-dependent (R,R)-butanediol dehydrogenase which catalyzes oxidation of (R,R)-butane-2,3-diol to (3R)-acetoin, of meso-butanediol to (3S)-acetoin, and reduction of acetoin. Allows the use of 2,3-butanediol as an aerobic carbon source.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Probable diacetyl reductase [
- Magnesium-activated aldehyde dehydrogenase, cytosolic
- Alcohol dehydrogenase 4
Sequence:
MRALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLHEYLDGPIFMPKDGECHKLSNAALPLAMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASSCADLHCWPHSKFYNSKPCDACQRGSENLCTHAGFVGLGVISGGFAEQVVVSQHHIIPVPKEIPLDVAALVEPLSVTWHAVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAKKLGVEVFNPSKHGHKSIEILRGLTKSHDGFDYSYDCSGIQVTFETSLKALTFKGTATNIAVWGPKPVPFQPMDVTLQEKVMTGSIGYVVEDFEEVVRAIHNGDIAMEDCKQLITGKQRIEDGWEKGFQELMDHKESNVKILLTPNNHGEMK
Protein: aspartate--tRNA ligase (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (Q585M3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Tyrosyl/methionyl-tRNA synthetase, putative
- proline--tRNA ligase
- aspartate--tRNA ligase
- Structure-specific endonuclease subunit SLX1 homolog
- leucine--tRNA ligase
- arginine--tRNA ligase
- glutamate--tRNA ligase
- glutamine--tRNA ligase
- isoleucine--tRNA ligase
- Amidase domain-containing protein
Sequence:
MSDPAQSDNTGANEATTANAPKSTNKKQNEKEARKAARLAEEAAKAAEKAALLLRFADVFGAAPLVQSKTYGSRKFTDIAVLSKDDADRVVTIRARVDTTRKKGKLAFTVLRDGVHSLQAMAAVSEEVPKEMVDFIGQLPCESVVDVEGTVCIAAQPITSTSQQDIELRINRIHVVSEALRVLPFTLADASRREDEEGIKINFDTRLACRWLDLRSPASNAIFRIQSRVGQYFRQFLIDSEFVEIHSPKIIATASEGGANVFKLGYFNRDAYLAQSPQLYKQIALQGDLKRVFEVGPVFRAENSNTHRHLTEFVGLDVEMRINEHYYEVLDLAEELFCHMFERLSGHNAELEAIKRQYPFEPLVWQMSAERMKELGVGAIEEDTEPTDTYKARVRNSNLRMLRINYPDCVALLNTVLETKLDPTDDINTTNEKLLGKLVKERYGVDFFISDRFPSAARPFYTMPCPNDERFTNSFDMFIRGEEISSGAQRIHDASLLLQRAQSLQVDLGPVSDYVDSFRLGAWPHGGFGVGLERVVMLYLGLHNVRLTSLFPRDPQRVTP
Protein: Mitochondrial transcription termination factor 4 (H7C316)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
VLDWHRLIPLTWACMARQTPHLGEQRRTTASLLRKLTTASNGGVIEELSCVRSNNYVQEPECRRNLVQCLLEKQGTPVVQGSLELERVMSSLLDMGFSNAHINELLSVRRGASLQQLLDIISEFILLGLNPEPVCVVLKKSPQLLKLPIMQMRKRSSYLQKLGLGEGKLKRVLYCCPEIFTMRQQDINDTVRLLKEKCLFTVQQVTKILHSCPSVLREDLGQLEYKFQKNTTSSFCPFSLLPLFPPTPLFPAPCFSG