wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (I3ISS5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MNHHHTQQQQQKAGEQQLSEPEDMEMEAGDPDDPPRIPQNPVINGNVAMADGHNNTEEDMEDDTSWRSEATFPFVVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAMLKIINYKDDEKSFSRRISHLFFHKENDWGFSNFMSWSDVTDPERGFVEDDKVTFEVYVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRRAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKGKKNIFESFKDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTFPPILHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKPDVKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEATEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQPVTDMDIPQQLVERLQEEKRVEAQKRKERQEAHLYMQVQMVTEDQFCGHQGNDMYDEEKVKYTVFKVLKSSTLAEFVQNLSQTMGFPQDQMRLWPMQARSNGTKRPAMLDYEADCNKSMIDLSDNENPWTIFLETVDPEMAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCERAGFQQGTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDTSELPTAKDYFRDLYHRVDVIFCDKTIHNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKAIWLNSMFREEEITLYPDKHGCVRDLLEECKKAVELSDKGSEKLRLLEIVSYKIIGVHQEDELLECLSPAASRTFRIEEIPLDQVDLDKENEMLIPVAHFHKEVFGTFGIPFLLKIRQGEPFREVMKRIQSMLDIQEKEFEKFKFAIVMMGRHQYINEEDYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRGRYTYLEKAIKIHN
Protein: Pathogenesis-related protein 5-like (Q19876)
Organism: Caenorhabditis elegans
Interaction partners:
- Pathogenesis-related protein 5-like
- Lysozyme-like protein 7
- Saposin B-type domain-containing protein
- Uncharacterized protein ZK1320.2
- NIM-2 protein
Sequence:
MALVKLTLALLLLALGADARTITIYNKCPFTIWPGILGPGNPAGGGFQLTAGQSRNIDVDDAWTAGRVWARTGCDGNFNCETGFCRNSEQCNGAGGVPPASLAEFTLKAWGGQDFYDVSLVDGYNLPVLIDPHGGSGCKRAGGCVKDINAECPAALSVKGHNGNTVACKSGCLGYNTDQECCRGAYGTPDKCHRSATAQMFKDACPTAYSYAYDDGSSTFTCRATASYTVQFC
Protein: Probable sucrose-phosphatase 1 (AtSPP1) (EC 3.1.3.24) (Q9C8J4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the final step of sucrose synthesis.
Interaction partners:
- Sucrose-phosphate synthase 1
- Sucrose-phosphate synthase 4
- Probable sucrose-phosphate synthase 3
- Probable sucrose-phosphate synthase 2
- Sucrose synthase 3
- Sucrose synthase 1
- alpha-D-xyloside xylohydrolase
- Sucrose synthase 4
- Sucrose synthase 6
- Sucrose synthase 5
Sequence:
MERLTSPPRLMIVSDLDETMVDHHKDPENLALLRFNSLWEDAYRHDSLLVFSTGRAQTMYKKLRKEKPLLTPDVIITSVGTEIAYGNSMVPDDNWVEILNKKWDRGIVQEETSKFPELTLQGETEQRPHKLSFNIDKSKVKAVTKELSPRLEKRGVDVKFIFSGGNAFDVLAKGGGKGQALAYLLKKLKTEGKLPINTLACGDSGNDTELFTIPNVYGVMVSNAQEELLEWYAENAKDNANIIHASERCAGGITQAIGHFKLGPNLSPRDVSDFLECKADNVNPGHEVVKFFLFYERWRRGEVENCTTYTSSLKASCHPSGVFVHPSGAEKSLRDTIDELGKYYGDKKGKKFRVWTDQVLATDTTPGTWIVKLDKWEQTGDERKCCTTTVKFTSKEGEGFVWEHVQQIWSEETEIKDDSNWII
Protein: Protein AC142 (P41700)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: Required for occlusion-derived virus (ODV) envelopment and subsequent embedding of virions into polyhedra.
Subcellular location: Host cytoplasm {ECO:0000269|PubMed:18045640}. Host nucleus {ECO:0000269|PubMed:18045640}. Virion {ECO:0000269|PubMed:18045640}. Note=Within virion, localizes primarily to the nucleocapsid fraction. {ECO:0000269|PubMed:18045640}.
Interaction partners:
Sequence:
MSGGGNLLTLERDHFKYLFLTSYFDLKDNEHVPSEPMAFIRNYLNCTFDLLDDAVLMNYFNYLQSMQLKHLVGSTSTNIFKFVKPQFRFVCDRTTVDILEFDTRMYIKPGTPVYATNLFTSNPRKMMAFLYAEFGKVFKNKIFVNINNYGCVLAGSAGFLFDDAYVDWNGVRMCAAPRLDNNMHPFRLYLLGEDMAKHFVDNNILPPHPSNAKTRKINNSMFMLKNFYKGLPLFKSKYTVVNSTKIVTRKPNDIFNEIDKELNGNCPFIKFIQRDYIFDAQFPPDLLDLLNEYMTKSSIMKIITKFVIEENPAMSGEMSREIILDRYSVDNYRKLYIKMEITNQFPVMYDHESSYIFVSKDFLQLKGTMNAFYAPKQRILSILAVNRLFGATETIDFHPNLLVYRQSSPPVRLTGDVYVVDKNEKVFLVKHVFSNTVPAYLLIRGDYESSSDLKSLRDLNPWVQNTLLKLLIPDSVQ
Protein: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B) (BAF60B) (Q92925)
Organism: Homo sapiens (Human)
Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- SWI/SNF complex subunit SMARCC1
- SWI/SNF complex subunit SMARCC2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
- AT-rich interactive domain-containing protein 1A
- Actin-like protein 6A
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
- AT-rich interactive domain-containing protein 1B
Sequence:
MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFRPMGPAGPAAQYQRPGMSPGNRMPMAGLQVGPPAGSPFGAAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGTAGTPGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT
Protein: Protein E7 (P06465)
Organism: Human papillomavirus type 1 (Human papillomavirus type 1a)
Function: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
Subcellular location: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04004}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04004}. Note=Predominantly found in the host nucleus. {ECO:0000255|HAMAP-Rule:MF_04004}.
Interaction partners:
Sequence:
MVGEMPALKDLVLQLEPSVLDLDLYCYEEVPPDDIEEELVSPQQPYAVVASCAYCEKLVRLTVLADHSAIRQLEELLLRSLNIVCPLCTLQRQ
Protein: Fluorescence recovery protein (FRP) (P74103)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Destabilizes orange carotenoid protein-R form (OCP-R), the FRP-OCP interaction accelerates the OCP-R to OCP-O conversion. Increases fluorescence recovery following non-photochemical quenching (NPQ) by OCP, most probably by destabilizing OCP-R binding to the phycobilisome core.
Subcellular location: Cellular thylakoid membrane {ECO:0000269|PubMed:20534537}; Peripheral membrane protein {ECO:0000269|PubMed:20534537}; Cytoplasmic side {ECO:0000305|PubMed:20534537}. Note=Very tightly associated with the membrane. {ECO:0000269|PubMed:20534537}.
Interaction partners:
- Orange carotenoid-binding protein
- Iron-regulated protein
Sequence:
MLQTAEAPWSQAETQSAHALFRKAYQRELDGLLATVQAQASQITQIDDLWKLHDFLSAKRHEIDGKYDDRQSVIIFVFAQLLKEGLVQAEELTFLAADKQSKIKALARL
Protein: Chromatin associated kinesin related protein (KLP38B) (O18390)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSNKSTPVRHASSSSRREESTNPMPASEMRKKVLMTRAEDREHRDRPEQLLNTAFSGSTPQPKPKPTALNACYTPSSLYRNAKLYSWKSKDARHREIPLQQDKGAGLSDEVLPQRVQESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHYEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVDFQLAHQEILQKQEQQLRSELEAEKRAALTKIEQERAQHARDFEERLQCLELEQFKYKCNSEMLETERQALALAQQQEHTPLRHEDAVSTPAQKSTILEDIQRIMLNPSEESLHKTQLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLGVWLDLVRDNAEQQEKLNATTIFQSVEVNWEPLDADLNETLSDTHNSSRIALNLSAMKDVLLNKPLKRLLNASSSKSNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFTTLVQQELQIMQRSAHRLRRHCEATLLERENHQDNGVLAVSLQEALARMDTVLNGMHTSLARAEATACVTSPTKTQKAVRFLID
Protein: Polynucleotide 5'-hydroxyl-kinase GRC3 (EC 2.7.1.-) (Protein GRC3) (Q07845)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Polynucleotide 5'-kinase involved in rRNA processing. Required for the efficient termination by RNA polymerase I and the processing of the IST2 pre-rRNA internal transcribed spacer localized between the 5.8S and 25S rRNAs. May act by maintaining the phosphorylated status of the downstream RNT1 cleavage product, which in turn allows the torpedo activity of RAT1 to efficiently terminate Pol I transcription. In vitro, displays polynucleotide kinase activity on both single- and double-stranded RNA and on single-stranded DNA alone, but not double-stranded DNA alone.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:20814424}. Note=Associates with rDNA.
Interaction partners:
- Protein LAS1
- Pre-rRNA-processing protein IPI3
- 5'-3' exoribonuclease 2
- Decapping nuclease RAI1
- Pre-rRNA-processing protein IPI1
- Pre-rRNA-processing protein RIX1
- Midasin
- Ribosome biogenesis protein YTM1
- Putative uncharacterized protein YLL044W
- Ribosome biogenesis protein ERB1
Sequence:
MVIDSKQDLPQYTKDSGSESDSDSSNNFIVESPSIPSSKSATVVLNSEEYEDDEGDDLNGLDAELIDNITYEGDEDETMFVGLKEKQKLHLSGVFRLQVVKGGIVYNNVHYNASREILTFWHPLSQSIPTIDFSHFAGWQDTFFMPRNNRFKIRDEEFKSFPCVLRVFNSNHTGLLEAGHLYRDVNYLWKPKEPYFPLNERTTYHLLHESDRIQSLSVPGYWSTPLEKLYLSHKNAAYDTRIMVIGGKNSGKSTFLRLLLEKFTQDIRDSTTSQEELVYLDLDPGQPEYSLPDSISLNKILSSPISLGQHLCQGSNFQTLLQFYAGSSSPQDEPTSYLNCADKLIDHLEEQAFFGTSLLNLPGWIKGFGMQILNHIIRKYKPTHLLFLETANSKRHLDELTIPQSFSTSLRDAYAPEVVRVPAHSLNHTLSSRFHASQLRTFKILALFHKITQFDYDFAPLLKSAPLQISYGKGKSGIKGIQFPMEFQDLNPQDIKSALEGTVIGIYTYSGEDSLEVKSLNTFPILQSCTSSSKNFITLGLIHSIDTSQQIMNIYVPPCHTQILDKQPEDAQWIIVRNKTETPFCDFLPSPRTITWDDNIQIPFATFERRKKLEHVWKVRKNVMRRGQFMKR
Protein: Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) (P53588)
Organism: Caenorhabditis elegans
Function: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03220}.
Interaction partners:
- Succinate--CoA ligase subunit alpha, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit
- Dihydrolipoyl dehydrogenase, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- 2-oxoacid dehydrogenase acyltransferase catalytic domain-containing protein
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Probable citrate synthase, mitochondrial
Sequence:
MIGRISQPLLNTSQKFMAPAARTLMLHEHHGMKILQNYEIKVPPFGVAQDAETAFSEAKRIGGKDYVVKAQVLAGGRGKGRFSSGLQGGVQIVFTPDEVKQKAGMMIGANLITKQTDHRGKKCEEVMVCKRLFTRREYYFSITLDRNTNGPIVIASSQGGVNIEEVAATNPDAIVKMPIDVNVGITKELAHEIAVKMGFSKDCEQQASEIIEKLYQMFKGSDATLVEINPMAEDVNGDVYCMDCKLLLDSNAEFRQAKLFDLKDKKQEDELEIRAAAANLNYIRLDGTIGCMVNGAGLAMATMDIIKLHGGEPANFLDVGGGATVEQVTEAFKIITADKDKVSAILVNIFGGIMRCDVIAQGIIQAARELDLKIPIVVRLQGTKVEDAKALIATSQLRILPCDNLDEAAKMVVKLSNIVDLARATNVDVKFELSI
Protein: Uncharacterized protein (Q57YP4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVKLTHEDTQRIKTAFLSYSQGQPKVTEQMMDQLICGAIPGISWEELQAKKGPKAAQGYDRSAFFSLVTSDDRYVQFIVANFPPAPEEEKAPQVDALELKTAKGF
Protein: Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) (Q9SVN5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:16251277, ECO:0000305|PubMed:16297076}.
Interaction partners:
- Lysine--tRNA ligase, cytoplasmic
- ATP binding / aminoacyl-tRNA ligase/ nucleotide binding protein
- Arginine--tRNA ligase, cytoplasmic
- Glutamate--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Proline--tRNA ligase, chloroplastic/mitochondrial
- Proline--tRNA ligase, cytoplasmic
- Aspartate--tRNA ligase 1, cytoplasmic
- Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g24130
- Isoleucine--tRNA ligase, cytoplasmic
Sequence:
MEDDGKSSPKLPIPGKRNILITSALPYVNNVPHLGNIIGCVLSADVYARYCRLRGYNAIYICGTDEYGTATETKALEENCTPKEICDKYHAIHKEVYDWFGISFDKFGRTSTPEQTEVCQAIFNKLWDNKWLSENTMQQLYCDTCKKFLADRLVEGSCPFEGCNYDSARGDQCEKCGKLLNPTELKDPKCKVCQNTPRIRDTDHLFIELPLLKDRLEAYIKKTSVTGSWSQNAIQTTNAWLRDGLRQRCITRDLKWGVPVPHEKYKDKVFYVWFDAPIGYVSITSCYTSEWEKWWKNPENVELYQFMGKDNVPFHTVMFPSTQLGTEENWTLMKTISVTEYLNYEDGKFSKSKGVGVFGNDVKDTNIPVEVWRYYLLTNRPEVSDTSFSWTDLQAKLNGELLSNLGNFVNRVLSFIAKPDNAGYGSVIPDAHDAESHSLTKSLAEKVEKFVAEYVEAMEKVKLKQGLKTAMLISSEGNYYLQASQFWKLYKEDKPLCAVVIRTAAGLVHLLAQLLEPFMPSFSCEVFKQLNLPPQFSLSDERGEVLLASRPWDILPPSHRIGTPQPLFKELENDEVARYREKFAGSQSDRRARDEAANLADQLNKTKLSDAKKQKASSKGGGKPKPQPAADREITMARLDIRVGKIVKAEKHPKADALYVEEIDVGGGEIRTVVSGLVKYIPLEEMQNRMVCVLCNLKPAKMRDIVSQAMVLAASSSDGSKVELVEPPKTANIGERVTFPGFEGEPDDVLNPKKKVWETLLVDLNTKENLVACYKDVPFTTSAGVCKVSSISNGTIR
Protein: Cyclic nucleotide-gated ion channel 2 (AtCNGC2) (Cyclic nucleotide- and calmodulin-regulated ion channel 2) (Protein DEFENSE NO DEATH 1) (O65718)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as cyclic nucleotide-gated ion channel. Permeable to potassium and calcium in a cyclic nucleotide-dependent fashion (cAMP or cGMP). Could also transport lithium, cesium and rubium and displays a strong selectivity against sodium. Seems to directly participate in pathogen-induced calcium influx. May function in homeostasis, re-establishing ionic balance after defense action and/or other stimuli. Could mediate the initiation of the developmentally regulated cell death programs.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Calmodulin-7
- Calmodulin-1
- Calmodulin-like protein 10
- Calmodulin-6
- Calmodulin-2
- Calcium-binding protein CP1
- Topless-related protein 1
- Protein EDS1
- Protein CPR-5
- Serine/threonine-protein kinase BIK1
Sequence:
MPSHPNFIFRWIGLFSDKFRRQTTGIDENSNLQINGGDSSSSGSDETPVLSSVECYACTQVGVPAFHSTSCDQAHAPEWRASAGSSLVPIQEGSVPNPARTRFRRLKGPFGEVLDPRSKRVQRWNRALLLARGMALAVDPLFFYALSIGRTTGPACLYMDGAFAAVVTVLRTCLDAVHLWHVWLQFRLAYVSRESLVVGCGKLVWDPRAIASHYARSLTGFWFDVIVILPVPQAVFWLVVPKLIREEKVKLIMTILLLIFLFQFLPKIYHCICLMRRMQKVTGYIFGTIWWGFALNLIAYFIASHVAGGCWYVLAIQRVASCIRQQCMRTGNCNLSLACKEEVCYQFVSPTSTVGYPCLSGNLTSVVNKPMCLDSNGPFRYGIYRWALPVISSNSLAVKILYPIFWGLMTLSTFANDLEPTSNWLEVIFSIVMVLSGLLLFTLLIGNIQVFLHAVMAKKRKMQIRCRDMEWWMKRRQLPSRLRQRVRRFERQRWNALGGEDELELIHDLPPGLRRDIKRYLCFDLINKVPLFRGMDDLILDNICDRAKPRVFSKDEKIIREGDPVQRMIFIMRGRVKRIQSLSKGVLATSTLEPGGYLGDELLSWCLRRPFLDRLPPSSATFVCLENIEAFSLGSEDLRYITDHFRYKFANERLKRTARYYSSNWRTWAAVNIQMAWRRRRKRTRGENIGGSMSPVSENSIEGNSERRLLQYAAMFMSIRPHDHLE
Protein: RRM domain-containing protein (A8DYS0)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSGAVLPAVLVVPKMESVVVPIAESTVINAKDTTPSTAADNDVSPSPSEPDTDAIKMFVGQIPRQWNETDCRRLFEKYGSVFSCNILRDKSTQASKGCCFVTFYHRKDAIEAQGALHNIKVIEGMHHPVQMKPADTENRNERKLFIGQLSKKHNEENLREIFAKFGHIEDCSVLRDQDGKSRGCAFVTFTNRSCAVVATKEMHHSQTMEGCSAPLVVKFADTQKDKDVKTKSMITGSGAGSPKGGAASLLQNLNPALLQQLGGGQNYQAVASLLSLINGQQGQQQQHQQQQNVLGILGTGNPLLGNPAMAAQNQFDAITMAQIAHQQQMLALQGFAVQQGAPSQQQQGLFLAHQYSTNYSTGSPDSASNATDSSSDDNNVMNNRLTPTSKMAQYGYGPLIPRHPAQLYLQQRFPATAAAYVPGLAGGMAGAKTTSPVAASLANHQQIALTPFAGGAAALDHFQAMQQYALLANLQATGGVGVQATTSAAQMVGNGDVKGPDGANLFIYHLPQDFGDSDLINTFAPFGGILSAKVFIDKVTNLSKCFGFVSYENAQSATNAISAMNGFQIGSKRLKVQLKVDRGNPYNR
Protein: Syntaxin-61 (AtSYP61) (Osmotic stress-sensitive mutant 1) (Protein SYNTAXIN OF PLANTS 61) (Q946Y7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Vesicle trafficking protein that functions in the secretory pathway; the fusion of phospholipid vesicles containing SYP61 and VTI12 is triggered by YKT61 and YKT62. Together with VTI12, required for membrane fusion. Involved in osmotic stress tolerance and in abscisic acid (ABA) regulation of stomatal responses. Plays a role in the exocytic trafficking of cellulose synthases (CESAs) and the transport of cell wall components to the plasma membrane. Together with SYP121, regulates the post-Golgi trafficking of the aquaporin PIP2-7 to the plasma membrane, thus modulating cell membrane water permeability.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:11739776, ECO:0000269|PubMed:15342965, ECO:0000269|PubMed:21826108, ECO:0000269|PubMed:23832588, ECO:0000269|PubMed:25082856}; Single-pass type IV membrane protein {ECO:0000255}. Prevacuolar compartment membrane {ECO:0000269|PubMed:23832588, ECO:0000269|PubMed:25082856}; Single-pass type IV membrane protein {ECO:0000255}. Note=And along the cell wall inner surface (PubMed:23832588). Intracellular trafficking is modulated by TNO1 (PubMed:21521696). {ECO:0000269|PubMed:21521696, ECO:0000269|PubMed:23832588}.
Interaction partners:
- Tlg2p-like protein a
- Vesicle transport v-SNARE 12
- Vacuolar protein sorting-associated protein 45 homolog
- Syntaxin-121
- Syntaxin-42
- VAMP-like protein YKT62
- Putative syntaxin-24
- VAMP-like protein YKT61
- Syntaxin-43
- Syntaxin-21
Sequence:
MSSAQDPFYIVKEEIQDSIDKLQSTFHKWERISPDMGDQAHVAKELVATCGSIEWQVDELEKAITVAAKDPSWYGIDEAELEKRRRWTSNARTQVRNVKSGVLAGKVSSGAGHASEVRRELMRMPNSGEASRYDQYGGRDDDGFVQSESDRQMLLIKQQDEELDELSKSVQRIGGVGLTIHDELVAQERIIDELDTEMDSTKNRLEFVQKKVGMVMKKAGAKGQMMMICFLLVLFIILFVLVFLT
Protein: Inheritance of peroxisomes protein 2 (Q03824)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for peroxisome inheritance. Acts as the peroxisome-specific receptor for the myosin V motor MYO2.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16678774}; Single-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16678774}.
Interaction partners:
- Myosin-2
- vacuole-related protein 17
- Inheritance of peroxisomes protein 1
- GTP-binding protein YPT11
- GTP-binding protein YPT32/YPT11
- Vacuolar protein 8
- Protein BIM1
- Mitochondrial MYO2 receptor-related protein 1
- Peroxisomal biogenesis factor 3
- Peroxisomal membrane protein import receptor PEX19
Sequence:
MTTNSRPSALQAPGLQIFSMLKSSEEDGFMSSSLTLDSDNIIGVTENNRQEFYSTWRKPSLLSSRSVLHEYSPTIVGSNDCTFSPITVGKTTKFFNWDDIISRIFMQQPFGVTHQFFEEFRYSIITSHFLNDMNHYRLSLHLDQSIMNFHKSSTLLKNVPPKSVPFMATKYGKLAVAEDKKLYFRQNFNYLSMIITSYRVLTQLKKYCRKKNSPGLKRVVILILVAVYLSIQQEYFRRHLICYKTLLKVRKVLESLQQVDVMIHKYHLRFKEIKNHSFISRVSLISIADEHSSVIKELLVFSSDALFYKLKSIIPDIVIFSDTSELSKYCELYGIDVPNLYYNNTTTVKDLDGKLYRLKLLKKFMLCCLLSLDMTGNENLSNVNMRNALNKIFPDYMARVQLKKKYNPIGTFQNIVSLLRGLHSLLSTVLVSLNDHKQILYAFPEETSTNTGCERANVCSFSKNDKLFQALNYLKMIENNLLAIDIRNGITENDRNIIEDKLEELITFWKTSKICGNISRIQKVSPTNTINHGFHLDILKGRKSPRSSSVQGLSLERKVDFIDVAESVNDSFENDTELEEYEDYDCQEECSAGSRQNHRVDFIGKDSCRKPDFKQLSDNELRRKLDERILKLAQENREGRERLRTAKSFELLRKAQASMSVKFGFQKPLRDDAFLESRPLSKCKVSSEETIPFLYELKGLLGNDS
Protein: SibL (C0LTM6)
Organism: Streptosporangium sibiricum
Interaction partners:
Sequence:
MSSELSALVPVLFGHAAFQQLNAGCQLGLFELLHERGPLSAEEVADALRLPRRSADILLLGTTALGLSTVTDGGYRNGAPIGAAFRDGLWPVLRDIVQYQDKIAYQPAADYVESLRTGQNAGIRHFPGTTRDLYSRLAAVPGLEELFYRGMHAWSQLSNPVLLAQPDFTRVHRVLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADIFTDSYPAGHDCVLFAHQLVIWSPEQNLTLLRKAYDAVEPGGRVLVFNAFTDDDRTGPLYAALDNVYFTTLPFRHSTIHRWADCESWLREAGFTDVGRTAPPGWTPHGVVSGSRPR
Protein: Spermine oxidase (A0A8I6A6T7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGRRIPKDVVEEFSDLYNEVYNLTQEFFRNGKPVNAESQNSVGVFTREKVRNRIRDDPDDTEATKRLKLAMIQQYLKPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP
Protein: Zcf5p (A0A1D8PME2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MELEASDSNSFSMSTNETGKANPNVQIVQDGKVVKKVQKTRQRRILSCVYCHSKKIKCDRQKPCSQCTKLGMECKYFINERISRGGKKSSRLTADEKKLRGLMNSANENKKAKQESVETAKSQDTQSSSSSSPTNSSTTSTANPLAPSSSIATSIEEVEQQQFDTAPNTKDYTANPNQSQQEQLGIEDETFKTPSGLDISVSLLGFSNKPEASSNSNSLRSFTANVESPFSGADPFAIGGLIQSPMVNQATNSMTSSYFNHNFTTQATNHNNSINGANNQINFNSSSFPLANSDVSITFSSHANSPTMNFSERLQQQQQQQQQIPPRPESASIVKTQPQSSTLYNSLNGYTINTATSVNYLYGTNTYGENSTILNDITEYLPTDKDRSFELIDRYLNSVHLLLPIVVNMKEFLVQHKLYWEIKSRRDSTTADLNNPRVESPGSSHHSGDGGNEPMPSDSNFNYIQFYTLYLPILYASTISEFEEYDNLLLNQEIHKYLMGFKICKKYYNFPEGIKTIPLLLGNVIIQSTSPNPSTMEMAQIIRYAKFLHFHKDPWITLRIKDPEIIKFRRLLWWVIFGLDALSSHNFCLPPNCRSDDFNVLMPDEEEFIGGEKKLNVSIVSMNIKFGYDILLSEIVYHLHNGLCVNINCHQINQLKQSILSYQEQIKKYISKMDKYFQSKQIFADTLNHSPIQLLNVVNFVKIHSWSFLDRALMLLHKKILLGTPKNHNHNDEIENEIVQLGLKEPVMQIRANENPLSLCKFEDTYGQILEANIITNFNNSSISLLKFGDFENFSYGDLANNLIPSILHNFNDFLLYNDFIKFGKFNWFIKRTIPIDSVILLMIIISVKFKYQFITTEELSTYKNLINSVMYIINRKWFKNEKYKRMLSLTNMTWEYLLKKFDVNDVIAFDVKNSEGAKDLVSVNIMDTSQLKEKILYDLRHNFIDVVDYCSFYSSLENLLNELIKYIESK
Protein: Transcription factor hamlet (Q8I7Z8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor that plays a crucial role in external sensory organ (ESO) that elaborates from a single precursor cell (ESOP cell). Mediates the differentiation of lineage branch that generates the internal 'ES' and 'th' cells (external sensory neuron and thecogen cells, respectively) from the IIIB cell. Its absence leads to re-specification of IIIB daughter cells into external tormagen cells (tr cells), or internal multidendritic neurons (MD cells). One of its role in the development of the ESO lineage is to modulate the activity of Notch and PAX2 signals.
Subcellular location: Nucleus {ECO:0000269|PubMed:12193790}.
Interaction partners:
- RT01151p
- Trithorax group protein osa
Sequence:
MDAFFKDRAQAEHILQEWVRRREPVCELDIRDSGGVYAKTPLQRGTRYGPFPMKLSHQPNDPQLAWKAHSRHYNGWLEPTEDVSTWLKKIRSVQDDCIGEANLQSYINAGYLWYETNRYVNAGSEMVVDGRPKSPVQLNEDFMNGGKVLAAAAAAAAAVVAASSSGAKSGGGGSSAPSDDRSDRDNGSLYSGDEFSKDKKNSSLIREGDIDFTDDENGFDIRCEVCDKVYPDLDLLDDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGPGPYRNQHVNRHHQHPHQHPLPHQPHLAATATSTCPAPPRESSESSSSAAAAAVAAMSTPPNPFLMFRTAPSFFPGFPPYGFPPFLPQNPLHPTNIPMFFSKNPMDLGCGGPEITSPVSAFDQKLPFGFLKGENSESQAYDKVTEKELVFKAEEKLKKEPLVQAFEGEEDESRSSLDIKGKLEDTRNDSKSEEQDDMKQEPERVSTPDQQQAEDDRKSIDIMSTPPPADTPSGGDGPLDLSICRKRSAGSFFTAPAEDNLMLHRFMPRLHEFEAERGQPLKMRKSHSSAESSTSQKSHKGSSPTPTPTASPGLTPSPSPPTSAGGELSSTSEGGAVPTMAAAAFAADHSALASGPTLPQTHPTFHPLLLEEIYRSGFPFLCQPGGRRGIEALLAGAASAAAPKRPLPPVKFSAGSVVGLKTKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHESEGNNFRDSPSSSGIAEREEYFDDIRKFMNRVYTPNSLAGNEGDTEEYPNSDDQSVNLEKDSGNFNNNSSNISNNNSSSGNNNNSSKAITISS