wanglab/gogpt-training-data huggingface dataset:
Protein: rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (Q22053)
Organism: Caenorhabditis elegans
Function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins (By similarity). Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (By similarity). Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity). Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity). Plays a role in modulation of nucleolus size most likely through regulating the ribosomal RNA (rRNA) pool.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:22768349, ECO:0000269|PubMed:36329008}. Nucleus, nucleoplasm {ECO:0000269|PubMed:22768349}. Note=Fibrillar region of the nucleolus. Predominantly localizes to the nucleolus, but also localizes to small punctate structures throughout the nucleoplasm. Co-localizes with dao-5 in nucleoli. Localizes to a sub-nucleolar compartment in pachytene germ cells (PubMed:36329008). Co-localizes with garr-1 in nucleoli (PubMed:36329008). {ECO:0000269|PubMed:22768349, ECO:0000269|PubMed:36329008}.
Interaction partners:
- WD_REPEATS_REGION domain-containing protein.
- Putative H/ACA ribonucleoprotein complex subunit 2-like protein
- Small nuclear ribonucleoprotein associated homolog 13
- Putative H/ACA ribonucleoprotein complex subunit 4
- Nucleolar protein 56
- Nop domain-containing protein
- WD_REPEATS_REGION domain-containing protein
- Nucleolar protein 6
- WD repeat-containing protein 46
- Periodic tryptophan protein 2 homolog
Sequence:
MGRPEFNRGGGGGGFRGGRGGDRGGSRGGFGGGGRGGYGGGDRGSFGGGDRGGFRGGRGGGDRGGFRGGRGGGDRGGFGGRGSPRGGFGGRGSPRGGRGSPRGGRGGAGGMRGGKTVVVEPHRLGGVFIVKGKEDALATKNMVVGESVYGEKRVSVDDGAGSIEYRVWNPFRSKLAASIMGGLENTHIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLGVAKKRPNVVPIVEDARHPHKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGGHAVISIKANCIDSTAEPEAVFAGEVNKLKEEKFKPLEQVTLEPYERDHAVVVAVYRPVKGKKV
Protein: Xylan O-acetyltransferase 12 (EC 2.3.1.-) (Protein trichome birefringence-like 2) (OsTBL2) (Q2RBL8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan. Catalyzes the 2-O-acetylation of xylan, followed by nonenzymatic acetyl migration to the O-3 position, resulting in products that are monoacetylated at both O-2 and O-3 positions (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q2QYU2}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MWSALFSHLREVHKRSGVKEEKLIMKSPAAAGEAAGCHKPQATATNKMTVLQSPLGLRTILTSLVAFFIVVSSVSLLFDRSQDAQAQLAVAQHQHQEVQLKQKPASAAVGEQKSVFVDQSSLRSQEAQVQWTSELQDVATDSGDGGVDGEEECNWSLGRWVYDNSSRPLYSGLKCSFIFDEVACDKYGRNDTKYQHWRWQPHGCNLPRFNATKFLEKLRNKRLVFVGDSVNRNQWVSMVCMVEHFIPDGRKMRVYNGSLISFKAFEYNATIDFYWSPLLLESNSDNPIIHRVEYRIIRADRIEKHANVWKDADFIVFNSYLWWRKQRDGMTMKVMYGSFEDGDAKLDEVEMVDGYEIALKKLTEYLGANINKNKTRIFFAGSSPAHSWASNWGGDDNNKCLNETEPIQIEDYRSATTDYGMMDKAKEIFGTLEPKGIHVQILNITQLSEYRKDAHPTIFRRQYVPLTKEQIANPSIYADCTHWCLPGVPDVWNEFLYAYLMHK
Protein: Heterogeneous nuclear ribonucleoprotein U like 1 (M0R0K8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVC
Protein: Zinc finger protein GLI2a (Zinc finger transcription factor gli2) (Q9YGS4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
METTSPTSTEKKELKPSVLDGSSFTDLPKKPSPTTASRAPHLFSTFHTPIPIDMRHHEGRYHYEPHPLHPMHGPHGLAGSPVISDISLIRLSPHAAATGESPFNPPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPAELTHEHLKERSLFGLPPPPPGANPSEYYHLIASHRSPYGDLLMQTGAAAAHLPDYMSPVDMSRFPSPRLTPRVSRKRALSISPVSDASIDLQTMIRTSPNSLVAYINNSRSSSAASSSYGHLSVGAISPSFTFPHPITPVAYHQLLSQQRGLNAFGHTPPLLQPSPALSSRQQTLVAAAALNNTTSSSTSSSTADTSTESSQNAGGDPAVSSTVNPMIFKRSKVKTEAEGPHPISPGSQDHLELREELDKDECKQEPEAVYETNCHWEGCAKEYDTQDQLVHHISNDHIHGEKKEFVCRWVECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDAPPKPHPPKGNGENEAHTKHVRGRTDGSGEANSTTRGVEDCQHVKTIKTENTVMYQSSPGGQSSCSSEPSPLGSATNNDSGVEMAMHSGGSLGDLSALDDTPVVDSTGSPGTSAGVGLQLRKNRAGLLQLEHIKKEKLKTVRDSCSWANAPPQVRNTKLPPIPSIDSLLDAPNMGTQMSVPPTQHLGDLSSYEMTMLNQLHERRDSSTSTMSSAYISRRSSGISPCYSSRRSSEASQFGVRNNNVSSADSYDPISTDLSRRSSEASQCGGTGGLPSLLNLTPAQHYSLKAKYAAATGGAPPTPLPNMDRMSLKTRMAMYNDSQDSSAHLHHAQGVVNSRRCSDTGYGAPGMMPHEVPANLPRRASDPVRRTTLDPLSLPRVQRFNSISNMNLSRLPAYDRRAFNMQNNTWSDGSLHRHPFSQRPPSISENILMENMATDGGDQQGDDLVLPDDMVQYLRSQNGNSNHDSGISVNGGHALEFHGNMTSQQQQFYGQRRMGMAGINGSHVEPVPEQIADPQGMNKNNMPVQWNEVSSGSADAVSRVPKQQQQQLRGNLTVVQQKQNFGSYQGFGSNQQIVPMSQNLASLQQAYPQRNIQRMNTVQQFRQSISNPCQNIGEQVNRQDLSYNSNQRLICNSMGPPNGRMVQNQELQNYRSNLMHMNNINQQNYVPLTQTAFQNAGRGLIQPRPPSEPKPLNRQHSGSGMVQPNGCSLSNVNSSEASPKRPGEVGQHSNGNGTMYYSGEIHMLDNGIDYGSPMSPCTNQAPVASVSTMASPGVNQVTSTVDSTQSLDHTQIDFDAMLDDGDHSSLMSGTLSPGLLQSISQNSSRLTTPRNSVTLASVPAGIGNMAIGDMSSMLTALAEESKFLNMMA
Protein: Small ribosomal subunit protein uS11c (30S ribosomal protein S11, chloroplastic) (Q6ENE1)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS8c
- Uncharacterized protein
- Small ribosomal subunit protein uS7cz/uS7cy
- Small ribosomal subunit protein uS12c
- Small ribosomal subunit protein uS14c
- Large ribosomal subunit protein uL14c
- S5 DRBM domain-containing protein
- Small ribosomal subunit protein bS18c
- Large ribosomal subunit protein mL46
- Small ribosomal subunit protein uS4c
Sequence:
MTKAIPKIGSRRKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
Protein: Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (Myosin heavy chain, cardiac muscle beta isoform) (Q910C5)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm, myofibril, sarcomere {ECO:0000256|ARBA:ARBA00004204}.
Interaction partners:
Sequence:
MEALLGAAAPFLRAPEGPRPTPAGDTRGLCFVPHPQLEFIRARVTARAGNGVTVTTEMGETLTVPEADVHPQNPPKFDRIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRTEVPPHIFSISDNAYQNMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGHRKKEVANSSKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLEMLLITNNPYDYSYVSQGEVTVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHFGNMKFKQKQREEQAEPDGTEDCDKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVVRINNSLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLFDNHLGKSANFGKPRNVKGKSEAHFSLIHYAGTVDYNIIGWLEKNKDPLNETVVGLYQKSALKLLASLFSNYAGADAGGDGGKGKGAKKKGSSFQTVSALHRENLNKLMANLKTTHPHFVRCLIPNERKEPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIPNPTAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSLIITRIQAQARGQLMRIEFKKILERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMQTMKEEFGHLKEALEKSAARRKELEEKMVSMLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEEEEEMNAELAAKKRKLEDECSELKKDIDDLELSLAKVEKEKHATENKVKNLTEEMAGLDENITKLTKEKKILQESHQQALDDLQAEEDKVNTLAKAKGKLEQQVDDLESSLEQEKKIRMDLERAKRKLEGDLKLAQESIMDLENDKQQLEERLKKKDFELNTLNARIEDEQAISAQLQKKLKELQARIEELEEELEAERTGRAKVEKLRSELLQELEETSERLEEAGGATSVQLELNKKREAEFQKLRRDLEEATLQHEATAATLRKKHADSVAELSEQLDNLQRVKQKLEKEKSELKLELDDVNSNTEQLIKAKTNLEKMCRTTEDQMNEHRSKLEEAQRTVTDLSTQRAKLQTENSELSRQLEEKEAFINQLTRGKLTYTQQLEDLKRQLEEEAKAKNALAHALQSAQHDCDLLREQYEEEMEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMADVERSNAAAAALDKKQRNFDKILSEWKQKFEESQTELEASQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEILDLTEQLGASQKSIHELEKVRKQLDAEKLELQAALEEAEASLEHEEGKILRAQLEFNQVKADYERKLAEKDEEIEQSKRNHLRVVDSLQTSLDAETRSRNEALRLKKKMEGDLNEMEIQLSHANRTAAEAQKQVKALQGYLKDTQLQLDDVVRANEDLKENIAIVERRNNLLQSELEELRAMVEQSERARKLAEQELIEASERVQLLHSQNTSLINQKKKMEADISQLQTEVEEAIQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQLQKLEVRVRELENELEAEQKRNAESIKGLRKSERRVKELSYQTEEDRKNMVRLQDLVDKLQLKVKAYKRQAEEAEEQANSNLAKFRKVQHELDEAEERADMAESQVNKLRARSRDIGAKKGLNEE
Protein: BcDNA.LD26519 (Debra, isoform B) (Debra, isoform C) (Debra, isoform D) (Debra, isoform E) (Debra, isoform F) (Q9V474)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Transcriptional activator cubitus interruptus
Sequence:
MDAQFEHLCRICAANTKSKTNSVVESVFIFKTQGLKDKISRHLYLNVAEEDPLPKVLCKSCYRQVEATASLSNIAKHTQLVFRDFLLSTLPKNAREAAAAQLSVPATQIPHRHDEVQAEIDEFRPILLTHVPESGNTASKPQPANCLELAPKTGENYLAASSSSSSLSKPAGSVKSYLNTGRRNSVFTDTRYGSAPLSIAQRTMQCLPSLVPLNTESLGSNAMRKSPDTKLSPKGVINFIQTHGRITGNIPEVQAEDNTGNINVTDSRNTVTASVLISSNVSNPGTKSQDSNLFLQKSRNLKNTLNNIKAMRTGQVSLLKGAQNRNPIEDVRPLVTTTLVPQYGGEPSVEEALPEHMIFAAPKKKREDEEQFLQTALPQLKKTVPSQSKTKSTKLDLTISVDSHVSPPSTSISNVKSLTDAIFLGSVIRDPDLLMLILKALKWPVTAENCDEQMSRLKSSKFAVIMSDTNLLQDTDLTQLLGPYLAPMLPVVQQQDQHPLSSAIGSASSNHSSQATKDVLKLADLSSAMPYKLPPETSVQLVPSSPTEQEPQPVRHKKAVSVPTVKRHQRKMRALDLPAVDKTRRIISLSTSKAAYVSNELSNINSVLFSQFESNPADAINEALISLLKQQQQETKDQRKTRQSCIGSDSAVNLEDIVLIDPQPPLAVDPHNVKYLEDDYVSPQSQPGSQYNFKRRKTDIRSSEPSEVVVLDNSGSPNEKNSKEVFPSTKQTLSRETKKSAVTVRKESLGQLKQAPTSTVPEDICDPKARAINAKENPEVCEPVPDNGGSDDIDDSKAGSVSVRKSEVKAALGQKLLEAIGLSQLGADAAPENSRDTLRSALKRSIKQAQEQQLQLKRGNHEEPVKQLADSTTKLSAAESADEHKKAIAERELALLNRGFKAGEENTISLKDDKWERTDVSSSSSRNRRGRKSKIDSNVEDFGDEEKKDSRWDEDDDLPLKADTEKPSERNSTNARPTRTSKTLSKYYKGPTSKSHHSMGTRSTRQR
Protein: Methyl-CpG binding domain protein 2 (A0A8I6AFM4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGAGGCGVGSSGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKLWFVTPTLIGL
Protein: Protein DOM34 (P33309)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in protein translation. Together with HBS1, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. The complex formed by DOM34 and HBS1 has ribonuclease activity towards double-stranded RNA substrates, but does not cleave single-stranded RNA. Acts as endonuclease; has no exonuclease activity. Increases the affinity of HBS1 for GTP, but nor for GDP. Promotes G1 progression and differentiation and is involved in mitotic and meiotic cell divisions.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Elongation factor 1 alpha-like protein
- Superkiller protein 7
- Translation initiation factor RLI1
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein eS30A
- Small ribosomal subunit protein uS12A
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS10
- Eukaryotic peptide chain release factor GTP-binding subunit
- Small ribosomal subunit protein eS7A
Sequence:
MKVISLKKDSFNKGGAVITLLPEDKEDLFTVYQIVDKDDELIFKKKFTSKLDEAGKKKSTDLVKLKIKVISEDFDMKDEYLKYKGVTVTDESGASNVDIPVGKYLSFTLDYVYPFTIIKQNFNKFMQKLLNEACNIEYKSDTAAVVLQEGIAHVCLVTSSSTILKQKIEYSMPKKKRTTDVLKFDEKTEKFYKAIYSAMKKDLNFDKLKTIILCSPGFYAKILMDKIFQYAEEEHNKKILDNKGMFFIAHCSTGYLQGINEVLKNPLYASKLQDTKYSKEIMVMDEFLLHLNKDDDKAWYGEKEVVKAAEYGAISYLLLTDKVLHSDNIAQREEYLKLMDSVESNGGKALVLSTLHSLGEELDQLTGIACILKYPLPDLDEDDGEE
Protein: Electron transfer protein, putative (Q388Y9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Acyl carrier protein
- NADH-ubiquinone oxidoreductase, mitochondrial, putative
- Reiske iron-sulfur protein, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial
- Uncharacterized protein
- Mitochondrial carrier protein, putative
- 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein
- Mitochondrial processing peptidase alpha subunit, putative
Sequence:
MRRFSNCLLCFGAITPVGDSKRFFKSDGTPYNRDAANNLYGSEHTHRGGVEALSEGVAAGQYGEHKPRAIMFVNKRPVEIIPQEENLLEVLEREGIRVPKFCYHPILSVAGNCRMCLVQVDGTQNLVVSCATVALPGMSIITDSRLVRDAREGNVELILINHPNDCPICEQATNCDLQNVSMNYGTDIPRYKEDKRAVQDFYFDPQTRVVLNRCIHCTRCVRFLNEHAQDFNLGMIGRGGLSEISTFLDELEVKTDNNMPVSQLCPVGKIYLGDADENNLIAEQLDVSYESECGDRGTVTLGK
Protein: MADS-box transcription factor 58 (OsMADS58) (Q2V0P1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor involved in the development of floral organs. Acts as a C-class protein in association with MADS3. Involved in the control of lodicule number (whorl 2), stamen specification (whorl 3), floral meristem determinacy and regulation of the carpel morphogenesis (whorl 4). Plays a more predominant role in floral meristem determinacy than MADS3.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MHIYKEQEAEPSTGLMMPEPAPVASPGSGGSGGSGSVGAEKIGSRGKIEIKRIENTTNRQVTFCKRRSGLLKKAYELSVLCDAEVALVVFSSRGRLYEYSNNSVKETIERYKKANSDTSNASTVAEINAQHYQQEAAKLKQQITNLQNSNRTLVGDNITTMNHRELKQLEGRLDKGLGKIRARKNELLCAEIEYMQRRETELQNDNMYLKSKVAESERGLQTVNMMGSASTSEYVQNMIHYDPRNFLQFNIMHQPQYYPEQEDRKAFMSDER
Protein: Armadillo repeat-containing protein 7 (Q9H6L4)
Organism: Homo sapiens (Human)
Interaction partners:
- RNA-binding protein 48
- Sodium channel modifier 1
- RING-type E3 ubiquitin-protein ligase PPIL2
- Cysteine-rich PDZ-binding protein
- G-patch domain and KOW motifs-containing protein
- BUD13 homolog
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
- E3 ubiquitin-protein ligase RNF113A
- RNA-binding motif protein, X-linked 2
- Splicing factor 3B subunit 4
Sequence:
MAQKPKVDPHVGRLGYLQALVTEFQETQSQDAKEQVLANLANFAYDPSNYEYLRQLQVLDLFLDSLSEENETLVEFAIGGLCNLCPDRANKEHILHAGGVPLIINCLSSPNEETVLSAITTLMHLSPPGRSFLPELTATPVVQCMLRFSLSASARLRNLAQIFLEDFCSPRQVAEARSRQAHSALGIPLPRSVAPRQR
Protein: Heterogeneous nuclear ribonucleoprotein A0 (B5XFP5)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MDNSSQLCKLFVGGLNVDTDDDGLRKHFEQYGQLTDCVVVVNKQLQRSRCFGFVTYSSAEEADAAMAARPHVVDGTNVELKRAVAREDAGKPEALAKVKKIFIGGLKDDIEDEHLNEYFSQFGEIEKAEVIAEKETGKKRGFGFVHFTDNDSADKAVVLKFHNINGY
Protein: BCL2 interacting protein 3 like (H0YBC7)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
EQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGCGN
Protein: Transcription factor bHLH70 (Basic helix-loop-helix protein 70) (AtbHLH70) (bHLH 70) (Transcription factor EN 13) (bHLH transcription factor bHLH070) (O81037)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor bHLH10
- Putative transcription factor bHLH041
Sequence:
MFVLRVSNQSFKLHQQVQCKDEIFCLDQKVNVRRSLQVQETVEDHQSFALEEEEQQLSTPSLLQDTTIPFLQMLQQSEDPSPFLSFKDPSFLALLSLQTLEKPWELENYLPHEVPEFHSPIHSETNHYYHNPSLEGVNEAISNQELPFNPLENARSRRKRKNNNLASLMTREKRKRRRTKPTKNIEEIESQRMTHIAVERNRRRQMNVHLNSLRSIIPSSYIQRGDQASIVGGAIDFVKILEQQLQSLEAQKRSQQSDDNKEQIPEDNSLRNISSNKLRASNKEEQSSKLKIEATVIESHVNLKIQCTRKQGQLLRSIILLEKLRFTVLHLNITSPTNTSVSYSFNLKMEDECNLGSADEITAAIRQIFDS
Protein: Armadillo repeat-containing X-linked protein 3 (Q8BHS6)
Organism: Mus musculus (Mouse)
Function: Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the Trak2-kinesin motor complex via its interaction with Miro and Trak2. Mitochondrial distribution and dynamics is regulated through Armcx3 protein degradation, which is promoted by PCK and negatively regulated by Wnt1. Enhances the Sox10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:19304657, ECO:0000269|PubMed:22569362}; Single-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:22569362}. Nucleus {ECO:0000269|PubMed:22569362}.
Interaction partners:
- Trafficking protein, kinesin binding 2
Sequence:
MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDAGDCSGARYNDWSDDDDDSNESKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHILANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKEYKEVILKLLIIFENINDNFKWEENEPAQNHFSEGSLFFFLKEFQVCADKVLGIESRHDFQVRVKVGKFVAKLTERMFPKSQE
Protein: AT-hook motif nuclear-localized protein 18 (Q9LZX7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity). Acts redundantly with AHL22, AHL27 and AHL29 in the regulation of flowering and regulation of the hypocotyl elongation.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8VYJ2}.
Interaction partners:
- Pentatricopeptide repeat-containing protein At3g53700, chloroplastic
- E3 ubiquitin-protein ligase RFI2
- Protein SHI RELATED SEQUENCE 3
Sequence:
MDEVSRSHTPQFLSSDHQHYHHQNAGRQKRGREEEGVEPNNIGEDLATFPSGEENIKKRRPRGRPAGSKNKPKAPIIVTRDSANAFRCHVMEITNACDVMESLAVFARRRQRGVCVLTGNGAVTNVTVRQPGGGVVSLHGRFEILSLSGSFLPPPAPPAASGLKVYLAGGQGQVIGGSVVGPLTASSPVVVMAASFGNASYERLPLEEEEETEREIDGNAARAIGTQTQKQLMQDATSFIGSPSNLINSVSLPGEAYWGTQRPSF
Protein: AMP deaminase (AtAMPD) (EC 3.5.4.6) (Protein EMBRYONIC FACTOR 1) (O80452)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: AMP deaminase plays a critical role in energy metabolism. Essential for the transition from zygote to embryo.
Subcellular location: Membrane {ECO:0000269|PubMed:16543243}; Single-pass membrane protein {ECO:0000269|PubMed:16543243}. Microsome membrane {ECO:0000269|PubMed:16543243}. Note=Might be associated with the inner mitochondrial membrane. {ECO:0000250}.
Interaction partners:
- Inosine-5'-monophosphate dehydrogenase 1
- Inosine-5'-monophosphate dehydrogenase 2
- Adenylosuccinate synthetase, chloroplastic
- Adenine phosphoribosyltransferase 5
- Hypoxanthine phosphoribosyltransferase
- Adenylosuccinate lyase
- Adenylosuccinate lyase
- Adenine phosphoribosyltransferase 1, chloroplastic
- Adenine phosphoribosyltransferase 3
- Adenine phosphoribosyltransferase 4
Sequence:
MEPNIYQLALAALFGASFVAVSGFFMHFKALNLVLERGKERKENPDGDEPQNPTLVRRRSQVRRKVNDQYGRSPASLPDATPFTDGGGGGGGDTGRSNGHVYVDEIPPGLPRLHTPSEGRASVHGASSIRKTGSFVRPISPKSPVASASAFESVEESDDDDNLTNSEGLDASYLQANGDNEMPADANEEQISMAASSMIRSHSVSGDLHGVQPDPIAADILRKEPEQETFVRLNVPLEVPTSDEVEAYKCLQECLELRKRYVFQETVAPWEKEVISDPSTPKPNTEPFAHYPQGKSDHCFEMQDGVVHVFANKDAKEDLFPVADATAFFTDLHHVLKVIAAGNIRTLCHRRLVLLEQKFNLHLMLNADKEFLAQKSAPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLREVFESLDLTGYDLNVDLLDVHADKSTFHRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLGEITKQVFSDLEASKYQMAEYRISIYGRKMSEWDQLASWIVNNDLYSENVVWLIQLPRLYNIYKDMGIVTSFQNILDNIFIPLFEATVDPDSHPQLHVFLKQVVGFDLVDDESKPERRPTKHMPTPAQWTNAFNPAFSYYVYYCYANLYVLNKLRESKGMTTITLRPHSGEAGDIDHLAATFLTCHSIAHGINLRKSPVLQYLYYLAQIGLAMSPLSNNSLFLDYHRNPFPVFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSACDLCEIARNSVYQSGFSHALKSHWIGKDYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQQVYLGKAVISDEVVP
Protein: Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein) (Q8CF97)
Organism: Rattus norvegicus (Rat)
Function: Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs) (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96JH7}. Cytoplasm {ECO:0000250|UniProtKB:Q96JH7}. Endoplasmic reticulum {ECO:0000269|PubMed:12473691}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:12473691}. Note=Associated with Golgi stacks and endoplasmic reticulum (PubMed:12473691). Displays cytoplasmic to nuclear translocation in response to DNA-protein cross-links (DPCs)-inducing agents (By similarity). {ECO:0000250|UniProtKB:Q96JH7, ECO:0000269|PubMed:12473691}.
Interaction partners:
- Transitional endoplasmic reticulum ATPase
- Ubiquitin recognition factor in ER-associated degradation protein 1
- NSFL1 cofactor p47
- Nuclear protein localization protein 4 homolog
- UBX domain-containing protein 2B
- UBX domain-containing protein 2A
- Syntaxin-5
- UBX domain-containing protein 7
- Cyclin-dependent kinase 1
- UBX domain-containing protein 7
Sequence:
MSQPPPPPPLPPPPPPPEAPQTSSSLAAAATPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDPVKDVLLPDYGLSNLTACNWCHGTSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWEGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDPSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRIGDVQGQELESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKGKAEGGPSTAAHSAHTVRQEEIAVTGKLSSKELQEQADKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASSNPHMDPRARETLAVRKHNTGTDFSNSSIKTEPPVFTAASSNSELIRIAPGVVTMRDGRQIDPDVVEAQRKKLQEMVSSIQASMDKHLRDQSTEQTPSDLSQRKVEAVSSSVRPGNLQTGLPESFSLTGGTENLNTETTDSRVADVLGAAFATRSKAQKENSMEEPEEMDSQDAETTNTTEPMDHS
Protein: Uncharacterized protein (Q385L8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 30S Ribosomal protein S17, putative
- Mitochondrial SSU ribosomal protein
- Mitochondrial SSU ribosomal protein
- Uncharacterized protein
- 30S ribosomal protein S8, putative
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Superoxide dismutase, putative
Sequence:
MLRCTVVGHHRSGKARAFVFRDPSLRMMRAGSGYQQLRRMGMPMQVGMGWRKVDSFHANTQYQHAWPLLSHDDLGNSDQSNNTKNIMYSMYMPKRNKGTAPWFRGADTYSVKYCEQGRYEYQRYLMINRFPSEYKKHFLSFLSNIRMSSGSATIPQEALHWLLRMIVDNFNPQHVHYIAAMKTLQSAGELDMARDVWKIMERQQTWPCTATICAYLDVCVEAGEKTWAMEAWNRYCTELKFLEPGEVDPKPISRVPFSLTREELLYLPKWKKHFDHDPNLDVMDLNRFNRTREVYLRMAQVMLAGGERNAFQHFFTKLEEAMLNKPTPVPEPPNPHLVRRPRWAPYEHCKSVHHSPWRLQNNGRALALGPSVTIEDEMQSRFFSNDQFLVHSVKEVLRIVLQEHKRAHPTECTRCKTEAFFYKTKDADETLKFCDDLIERLFASLGVRLSNLNTSSLLSTILEVFRVVGKESGAALLQRANEFLERKASLGDAEGSRENLTASNYLQVLSGFADESAFVYNTKKDGTCQYKTGFDPRTTMRHLADVVQEIAGNPHVTWAADMHLQVVETMVGCGTMKANDYFVRNVLRQFSWDSRFLEVLYVEYRRQDDVDMWAELTKRALVWTARYNAPASERLRRLIEDDYDTIRVQTRTFRELAVFQFRDVEERRHSRDVVNELPNPWYDYVAHALPFPDRDAGYPDEYGDLGQWRAPGGPGSPVRGPGYYAPPMEGEHQRGYTAEWRDLRNPMRPPEFPTPWERKYRQYARGQHPSYDMVYAGPMPEIFPMRRDFRKPTRWDFHDIEKQGKYRTSGPY