wanglab/gogpt-training-data huggingface dataset:
Protein: Krueppel-like factor 10 (EGR-alpha) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (Q13118)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O89091}.
Interaction partners:
- Paired amphipathic helix protein Sin3a
- Transforming growth factor beta-1 proprotein
Sequence:
MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ
Protein: O-GlcNAcase (EC 3.2.1.52) (RE69909p) (Q9VDC9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- glutamine--fructose-6-phosphate transaminase
- EGF domain-specific O-linked N-acetylglucosamine transferase
- UDP-N-acetylglucosamine diphosphorylase
Sequence:
MADEAGSQADGKRQFICGVIEGFYGRPWTTEQRKDLFRKLKSMGMGSSPSYMYAPKDDYKHRAYWRELYTVEEADHLSSLIAAAKEAGITFYYALSPGLDMTYSSPKEIATLKRKLDQVAQFGCEAYALLFDDIESELSKADKEVFQTFANAHVSVTNEIYTHLGSPRFLFCPTQYCASRAVPTVQESEYLNTLGSKLNNEIDILWTGDKVISKNISLESIQEITEVLRRPPCIWDNLHANDYDQKRIFMGPYSGRSPELIPHLRGVMTNPNCEFYGNFVAIHSLAFWSRCSLDSKVNSSLSADIKLETENDDDLPAEFLSKNVYHPRLALKNAITEWLPEFFMKKEAWGPITKPQPQVQMVMPIIPIIPSINTCMSLTTTTTTSTSSRTVPPTVNTTQLQALADVCVVTSSLTPISNPVMNSLVSPTKVITNDDIINPIPTTAASNIELPKKIPISVVPVPIMETKSVEASVELALDNAVFDDNEIEPNSDSVKERLELEVNLEGKQEPVANLSVDTMLDDDSLSPLSGVVNEPMECSSSITSQVSPREEEAIKVVADDVLMESVNDVHSMHVESGTSSPISNAEMREETEAQSDRTNDNNTIEGEGITVDDLVLLCDLFYLPFEHGSRGHKLLVEFNWLKGNANVILQDRSAGGGGDAIKSDKPEVSEWHQRREQFDQLCSAVVELLIKIANCPNKEICHELYSYMWDISGALSLLNCYVKWLALGHFPQNTSSYTEGSYTWFSKGWKEAFMSGDQEPWVFRGGLIADLQRLMPVDSGNDLFVYKLPEQPTANYYLLRPYCNSDEQQVNDLCTRLYLQWRGELDGGRHIPFPLPANVPNIVADGLIGGYLTLSPQLCIVAYDESNRIIGYSCAALDVNIFRRNLELCWYTELREKYSRDICPLEGGEEVVQLVTSLVESYHDSSGNGALDQCPVEVSGSFPAVLISGTLREAEERDSGITKRMLTVLLAALRANGCFGAHVRVPQQDVAQVNFYSRIGFVDVYREEATKCIYMGRRF
Protein: Putative cell-type specific agglutination protein pfl7 (Adhesin pfl7) (Pombe flocculin 7) (Q9P5N1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed.
Subcellular location: Cell surface {ECO:0000305}.
Interaction partners:
- Putative GPI-anchored protein pfl2
- Putative beta-glucosidase
- Uncharacterized protein C19C7.05
Sequence:
MNSLKSLCLKCIVTLCLLVNAFAFDYASLQEQDENLLAACPQYITIYTNGPVPGTTTIYPTSNVASNTSENYPYTGSKSLSSSSILSNSTISTSSSTPITASVPTSSSILSNSTIPTTSPVPTTSSTPTSSSILSNSTIPSSSSISASTITTTIISGSTQFTTTFVDQSIDTVEVVIPTAGYITTTLTSGSSYPVSTTTLQTVSGTQSGLVEVITPSCGCNPENSFHLRLVGDSINPSYVYKNTNVSDPDEGNMYTSTEGNTEAVNVFYYDPTVERILTCDCVRPVYTIYTDDPDSSFDIIKNNNGTFTFVESSSGEIQTLHVSQYGALWITSPEYDGETGGMDDVGFRADDVILVAY
Protein: Disks large homolog 1 (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97) (Synapse-associated protein 97) (SAP-97) (SAP97) (Q811D0)
Organism: Mus musculus (Mouse)
Function: Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels (By similarity). Functional regulator of Kv1.5 channel (By similarity). May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q62696}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q12959}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q62696}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q62696}. Postsynaptic density {ECO:0000250|UniProtKB:Q62696}. Synapse {ECO:0000250|UniProtKB:Q62696}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q62696}. Cell junction {ECO:0000250|UniProtKB:Q12959}. Cytoplasm {ECO:0000250|UniProtKB:Q12959}. Apical cell membrane {ECO:0000250|UniProtKB:Q12959}. Note=Colocalizes with EPB41 at regions of intercellular contacts. Basolateral in epithelial cells. May also associate with endoplasmic reticulum membranes. Mainly found in neurons soma, moderately found at postsynaptic densities. {ECO:0000250|UniProtKB:Q12959, ECO:0000250|UniProtKB:Q62696}.
Interaction partners:
- Glutamate receptor 1
- Peripheral plasma membrane protein CASK
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Disks large homolog 4
- Glutamate receptor ionotropic, NMDA 2B
- Disks large homolog 2
- Glutamate receptor ionotropic, NMDA 2A
- Tyrosine-protein kinase ZAP-70
- Mitogen-activated protein kinase 12
- Lethal
Sequence:
MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPVTTWEIASLPSTAVTSETLPGSLSPPVEKYRYQDEEVLPPEHISPQVTNEVLGPELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVPPSSPIVPVTPALPVPAESTVVLPSAPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRKPASEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFRFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL
Protein: Type II secretion system protein H (General secretion pathway protein H) (Q59652)
Organism: Pseudomonas aeruginosa
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004377}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004377}.
Interaction partners:
Sequence:
MSYRSNSTGFTLIELLIIVVLLAIMASFAIPNFKQLTERNELQSAAEELNAMLQYARSEAVSQRRAISIQALKDKDWGKGLSIGVLASGSIAAPLRKHDGFRAATLTAKEKSAVEHLTFTANGTLVPPTERTFAICQNGKTDGGRVLSISQAGRIQLEPSSKAPQSCY
Protein: Leucine-rich repeat-containing G-protein coupled receptor 6 (Q3UVD5)
Organism: Mus musculus (Mouse)
Function: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- R-spondin-1
- R-spondin-4
- R-spondin-2
- R-spondin-3
- Leucine-rich repeat-containing G-protein coupled receptor 4
- Leucine-rich repeat-containing G-protein coupled receptor 5
- E3 ubiquitin-protein ligase ZNRF3
Sequence:
MHSPPGLLALWLCAVLCASARAGSDPQPGPGRPACPAPCHCQEDGIMLSADCSELGLSVVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPLAIRTLGRLQELGFHNNNIKAIPEKAFMGSPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSLNGATDIQEFPDLKGTTSLEILTLTRAGIRLLPPGVCQQLPRLRILELSHNQIEELPSLHRCQKLEEIGLRHNRIKEIGADTFSQLGSLQALDLSWNAIRAIHPEAFSTLRSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCAYGICASFFKTSGQWQAEDFHPEEEEAPKRPLGLLAGQAENHYDLDLDELQMGTEDSKPHPSVQCSPVPGPFKPCEHLFESWGIRLAVWAIVLLSVLCNGLVLLTVFASGPSPLSPVKLVVGAMAGANALSGISCGLLASVDALTYGQFAEYGARWESGLGCQATGFLAVLGSEASVLLLTLAAVQCSISVTCVRAYGKAPSPGSVRAGALGCLALAGLAAALPLASVGEYGASPLCLPYAPPEGRPAALGFAVALVMMNSLCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLWPSPRSPGPLAYAAAGELEKSSCDSTQALVAFSDVDLILEASEAGQPPGLETYGFPSVTLISRHQPGATRLEGNHFVESDGTKFGNPQPPMKGELLLKAEGATLAGCGSSVGGALWPSGSLFASHL
Protein: DNA-binding protein SATB (Special AT-rich sequence-binding protein) (Q546B3)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGANVNITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPTKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAETDQR
Protein: Uncharacterized metal-dependent hydrolase TatD (EC 3.1.-.-) (O08343)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Methionine--tRNA ligase
- Ribosomal RNA small subunit methyltransferase A
- Resuscitation-promoting factor RpfB
- 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Sequence:
MVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAAVALHPTRADALTDAARAELERLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWHIDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCFSSDAAMARTCVDAGWLLSLSGTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNRRPEEVALITTSNARRAYGLGWMRQ
Protein: Nuclear localization sequence-binding protein (p67) (P27476)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in pre-rRNA processing. Specifically binds nuclear localization sequences. Candidate for a receptor at the nucleus that may be involved in both RNA and protein transport (Probable). Binds telomeric sequences of the type (TG[1-3])n in vitro.
Subcellular location: Nucleus {ECO:0000269|PubMed:1706724, ECO:0000269|PubMed:23222640}. Nucleus, nucleolus {ECO:0000269|PubMed:12756332}.
Interaction partners:
- Nucleolar protein 56
- rRNA 2'-O-methyltransferase fibrillarin
- Pre-rRNA-processing protein ESF2
- Protein PXR1
- ATP-dependent RNA helicase DBP2
- Protein arginine N-methyltransferase 1
- Nuclear GTP-binding protein NUG1
- H/ACA ribonucleoprotein complex subunit CBF5
- Nucleolar protein 58
- H/ACA ribonucleoprotein complex subunit GAR1
Sequence:
MAKTTKVKGNKKEVKASKQAKEEKAKAVSSSSSESSSSSSSSSESESESESESESSSSSSSSDSESSSSSSSDSESEAETKKEESKDSSSSSSDSSSDEEEEEEKEETKKEESKESSSSDSSSSSSSDSESEKEESNDKKRKSEDAEEEEDEESSNKKQKNEETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFSSPRPNNDGGRGGSRGFGGRGGGRGGNRGFGGRGGARGGRGGFRPSGSGANTAPLGRSRNTASFAGSKKTFD
Protein: Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171) (P32004)
Organism: Homo sapiens (Human)
Function: Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12514225, ECO:0000269|PubMed:20621658, ECO:0000269|PubMed:22973895, ECO:0000269|PubMed:26891472}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q05695}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q05695}. Cell projection, axon {ECO:0000269|PubMed:20621658}. Cell projection, dendrite. Note=Colocalized with SHTN1 in close apposition with actin filaments in filopodia and lamellipodia of axonalne growth cones of hippocampal neurons (By similarity). In neurons, detected predominantly in axons and cell body, weak localization to dendrites (PubMed:20621658). {ECO:0000250|UniProtKB:Q05695, ECO:0000269|PubMed:20621658}.
Interaction partners:
- Neuropilin-1
- Ankyrin-2
- Contactin-2
- Signal transducer CD24
- Neural cell adhesion molecule 1
- Shootin-1
- CD166 antigen
- Ankyrin-1
- Epidermal growth factor receptor
- Ankyrin-3
Sequence:
MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
Protein: RIKEN cDNA 3830403N18 gene (Q9D6C3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MENWDLSSDEKQDWNAPELDLIEEQNPVTHDDENANPEEVVGDTRSPVQNILGKFEGDINKTLHIKRKRMETYIKDSFKDSNQKLEQLWKTNKQERKKINNKFCEQYITTFQKFDMDVQKFNEEQEKSVNNYQKEEQALKLSKCSQSQTLEAIKDMHEKYMEGLMNLETNNYNVLFDVDGELRKEMSVFKKDLMKHTLKYSSTFPSSD
Protein: Gustatory and odorant receptor 22 (Q7PMG3)
Organism: Anopheles gambiae (African malaria mosquito)
Function: Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. GPRgr22 and GPRgr24 together are sufficient for olfactory carbon dioxide-chemosensation.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MIHTQMEDAQYEIRHQVLNPNQRQQLEDRRRIKEQLHQLEQDNESPTHMYRRKLKIASDVNLLDQHDSFYHTTKSLLVLFQIMGVMPIMRSPKGVDMPRTTFTWCSKAFLWAYFIYACETVIVLVVARERINKFISTSDKRFDEVIYNIIFMSIMVPHFLLPVASWRNGSEVAKFKNMWTDFQYKYLIVTGKPIVFPKLYPITWTLCIVSWSLSLVIILSQYYLQPDFQFCHTFAYYHIIAMLNGFCSLWFVNCTAFGTASKAFAKELTDVLATERPAAKLTEYRHLWVDLSHMMQQLGKAYSNMYGIYCLVIFFTTIIATYGSLSEIIEHGATYKEVGLFVIVFYCMSLLFIICNEAHHASKRVGLNFQERLLNVNLTAVDKATQKEVEMFLVAIDKNPPTMNLDGYANINRGLITSNISFMATYLVVLMQFKLTLLRQSAKNAFISALKANLSRIRSLDADKVNT
Protein: CRS1 / YhbY (CRM) domain-containing protein (F4JNR2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000256|ARBA:ARBA00004229}.
Interaction partners:
- Tetratricopeptide repeat
- At1g11210)
- F28K20.8 protein
- Protein SPIRAL1-like 2
- Protein QUIRKY
- Myb family transcription factor PHL12
- NDR1/HIN1-like protein 1
Sequence:
MALCQFPLNLHTISSSTSSSPRFRRLQPLDTSTKPNFLIRRLRFHSFNHPVRFHTRELSVITATIDIDTHQRKKTKRKPKPGFFEEISDKWSSRISPKTEKLPWQKQEEQIQHHEDEEDEEGDESSSNLSSGNGLSDKRTDSNRLYSANEPWSFPRPSGYMSAPWVNNGGSKGVNFTTSSEQGIQSSSFHDVTTVDRYRRDNDSSDRAVDSDLDDGERGMIDSGNNKGIWRTRKSNTVEAERIVPEHELKRLRNVALRMVERVKVGSAGITQALVEAIHEKWEVDEVVKLKFSEPYSLNMKRTHEVLEKKTGGLVIWRSGSSVVLYRGISYKLKCVQTFIKQNNLEANPEIHRSVEARDYVQEDGNYPKNVPKEQLSELCELNDLLDEVGPRFHDWTGCAPFPVDADLLPGYVEGYRCPFRILPQGVKPCLSNTEMTEMRRLARTSPPHFALGRSRELQGLAKAMVKLWAKSAIAKIAIKRGVENTRNERMAEELKRLTRGVLVSRNKEYIVFYRGNDFMPPAVAEALTERQKEITEVLQAKEDQAREMASTRATLTSQAKSPKTQLLAGTLAETIAASSRWAPNASSVDIEELKRESASIKRAALIRDLELRLLYGKQKLRRAERDLAKVQKDLDPSELPTDSEIITEEERLLYRKIGLSMDPFLLLGRREVYDGTIENMHLHWKHRELVKVIVRGKSLPQVKHIAISLEAESGGVLVSVDKTMKGYAIILYRGKNYQMPFRLRPSNLLTRKKAFARSIELQRREALKYHVADLEERIELLKTGQDDDMETRNKSDEEEENLYLRVDESDFSSDEDESLEWESEKNETFLSSEGKEEEEA
Protein: Beta-hydroxyacyl-ACP dehydratase (P71860)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MTVVGAVLPELKLYGDPTFIVSTALATRDFQDVHHDRDKAVAQGSKDIFVNILTDTGLVQRYVTDWAGPSALIKSIGLRLGVPWYAYDTVTFSGEVTAVNDGLITVKVVGRNTLGDHVTATVELSMRDS
Protein: PRE-binding protein (Q8IJS7)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Histone H4
- Peptidyl-prolyl cis-trans isomerase
- Peptidyl-prolyl cis-trans isomerase
- Peptidyl-prolyl cis-trans isomerase
Sequence:
MGRKATTSSILEEKPVNKNSGVVNNMKDALMNDKKQGGSKLNEKKGSKVTELTSNAHMNGSIQKKKEENELENNKKLNHKNNLEENCVIKSKEVVKGGDQKNEGQAKKKNNNNNNNNKKKGTKENDMDKINQSGNTNDDKKKANKNNTTEGNEKNKGSNNKKYVGNKDENMKVELMDVTKNNNSTNTGINNSSNNNNNNKKKNNNNNNNNNNNNNKNKNNNNNNNIISNNNNNNNNNSDVKKDWKKEIKLKEDERKKSENDLKKKFVKLNKADNYKNINDKKEAEIKKKIEIENFISTINSTISRFNGQTTRPINMKLSSADMENKCKDAKSKKKKINPKNLEEIEEANTYINYLEEQLSITKNYENFKNFQNRLISLRKICEEKLKENLKSMNETKIQEKKLRFVDKIIKMKKEKQNVDITEADIIRKDYAIPTDTYNILMKPYNFLNRIQTKYFVYVDNNKLSLTNNNNMMNNNNNNNNNNNNNNNTFINSYDNKTNLHIAGCKDDIEQFISYLQNVNFNSENKNFVHLNNKIFKIMLNMYDGSFKKMEEDTNVFVHVDNDMLYYCGMKDDIENLKELIEKATNNEKNLLNKNISKNIKLDSILARGFNKSILKEIETNTNTLIRMNYDAKTFDASATIKGSKNSDIEEAEEKLNEILKNLDSEFVPFEEKEIFSLYKKCSYELNEIRKNLNLFIIRQDNGLSLVGKKDNITKALEILEYSKNIISNKTVKKKLTEEEAFLFNSNYRGQIKAKTGAEVKIFNKTNHKELNISGNKNDIDKALEMIEELLKKRKCTQVDINEKVIALLLSSKAQKIKDIEKDTCTSIQINKTSHVAQIYGHEDNIHLAKDVLENLVQSEGKEGKEGKFIPNNLYVTVEMNVETEHIGSVIGKKGRTINKIQEDTFAKKIHIDKENKKIYIHGTQKTVDAAQKEIQKILNRSKEEMSNNNNNNNSSSNGGAFNNSYHESRYNNRHSNNSSSAHHRKSHKSTSRSAPRSSHKSESKSKGVYINTNDEKAFPSLHDVTNMQSKKNKKLSQSNQTTNTKKHEQAPQIDKQTNKNEEDKENQPKNEVHAETDVTKNETQEKEEQQQEKKKDKQEENQELNQTEKEQEKEQEKEQEKEQEKEQEKEQEKQSNEN
Protein: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6 (Oligosaccharyl transferase subunit OST6) (Oligosaccharyl transferase 37 kDa subunit) (OTase 37 kDa subunit) (Q03723)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Can participate in redox reactions and is able to catalyze dithiol-disulfide exchange reactions with other proteins, albeit with relatively low efficiency. May form transient disulfide bonds with nascent polypeptides in the endoplasmic reticulum and thereby promote efficient glycosylation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Protein transport protein SBH2
- Protein transport protein SEC61
Sequence:
MKWCSTYIIIWLAIIFHKFQKSTATASHNIDDILQLKDDTGVITVTADNYPLLSRGVPGYFNILYITMRGTNSNGMSCQLCHDFEKTYHAVADVIRSQAPQSLNLFFTVDVNEVPQLVKDLKLQNVPHLVVYPPAESNKQSQFEWKTSPFYQYSLVPENAENTLQFGDFLAKILNISITVPQAFNVQEFVYYFVACMVVFIFIKKVILPKVTNKWKLFSMILSLGILLPSITGYKFVEMNAIPFIARDAKNRIMYFSGGSGWQFGIEIFSVSLMYIVMSALSVLLIYVPKISCVSEKMRGLLSSFLACVLFYFFSYFISCYLIKNPGYPIVF
Protein: Pcf11 cleavage and polyadenylation factor subunit, isoform E (Pcf11 cleavage and polyadenylation factor subunit, isoform H) (A0A0B4LFF9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEQLFQNYRDDERRIGEEYLSSLQDLNCNSKPLINMLTMLAEENINYAHIIVKVVEYYISQVAPEFKLPILYLIDSIVKNVKSSYVQLFGQCIVNIFLHAFESVQHSQSQVLEKVRERMYALRQTWNEVFPPSKMYALDVKVKRLDNNWPITAKQPTNKIHVNPAIHVNPDFLKPGLVPGMPGNPTITSDMEEILQAKTRELLELKKRKLELELEQTKKHLEEQERQLTQTTDAMVGAPIIMPAPTPAAICPPITDPGIAVHNQRAPGVMGNVGPVMHNMPVAPQLFANKPKVHPVNPALLNSVRQRDPRLARQMHAASSHPAAPARNDPRLEAKSSSSQKSSRSRSKSPVRNSSSRSGKSGSSSHSSSSSRKRSESKSSTTSSSSSSSDVRHKGVTASSSNQPTVKRSGKITSKDSDRYVRNGSPLGSAKRKSSSPSSSPSKSKRSTSHKSSSSRGKTSSLRSRSRSPVFMDVDLRTGVRSKSPESRAVAPSSLPLAGASLPASAKAPKDLEKRTPAASLVRQSSPSPSSSSISSQGNVSDALQLSINKLLQVQGGAGEKRPADALPPHIDGEEQPPQQKRSKSAKLDALFGSEDVDLRREILVVKPGVIVVEDDSMDECDVDKPTKKSGSPPKKATLEELRAKLANSARIQNKQGKSDKSRDQAVSQRLKQLAELKVNDDSQEAHDEKVRTILSQAQEMYENNGMNQEQYKDLVQKVVAINENSKIKESRRRDNDLERNAARDAVLRKRIPKLKGNENHSAGSPHTDGSPRYDDQPAAAPEKPSNKRDKTKREMKRRKPTKWGEQVDAGAAQRTAWQLANVNNNNNNNNNKRGGIQLPVQPQAGFRGMPWQQPPAMVLGQSAVPPPPQPPSMISMPPVPPVTMTKAINSLDNPMADVVRSITIDGGSKEIRFYNQVAIIFMDGDQPHEIGFQPGQRVIFIDHNEPLPLCFNDDYKPFHLDGQLHRIRFGFPSRELYIDEHWYEIYFGGPAVSVPIGNKLHIIKAEGPPPNVDIGRVRRDLVVGKINMIADAHTIVPLFLDARQQTFQLGAEQHSLQFVDSFQYALLDGQLQKMEYGGLPKGMMLNGGRSCFIRFGTLPKGVIAGKTHVADMVYIKTDAPAEPPKPPPIIVKPPPVVEQPKPAPVAVAPISLPAAAAALESLNINDLFQKLVSSGIIGGATAAPTLPAADSSAAKEPTASATEPSTASATVAPATLPAGPPAEPIKRIDLRKPESIKTRQAAVVAVLYLGMQCSSCGVRFPPEQTIKYSQHLDWHFRQNRRERDSTRKATSRKWYYDLNDWRQYEEIEDVEEREKNFLEAQGQPGGVEALDELSQQRSLDSPVPTCAAGRDDVDHCCDMCHEKFEQFYNEELEEWHLRSAIRVEDKIYHPLCYEDYKASLNPPTEVKSDQDVDMNNTDDNAMDTLIKVEDDEDEGTPNSSQPIFEDDDDDVIVLPNEEPSVTEIVDDDDEDEYVPGNVTRADMGNESQDKTESNSETKEPKKDQVELGEQQQNESANESDVEIQEPNIPFTDLDTYVEKEMDEATRAALLNVKIKEEPKDEYEEDEDDGFEDVGTVVSLLPLPEDEISIHSSETQTHTIGSSASPATIERPASVTSLSLPANEADELEQGDANTDTDAELNGEKQEATHNLSAVGPALPLASIVNKIKINITKNTSSNSHNSASNTTTTDSQVSAISVIGGSGAAGGASGAGDPVQQVNAIQTISTIPVLCGGNTFVPKIATSTPSNVISSISVIGSTYGASSSSNGSRSTTSTASSAPAASLLAETGSLKSPTPPLATVDPDPEPVVEQKPALRNATLKRTKKVQNGIETSGLCSIM
Protein: Peripherin-2 (Retinal degeneration slow protein) (P17438)
Organism: Rattus norvegicus (Rat)
Function: Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity).
Subcellular location: Membrane {ECO:0000250|UniProtKB:P17810}; Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P15499}. Photoreceptor inner segment {ECO:0000250|UniProtKB:P15499}.
Interaction partners:
Sequence:
MALLKVKFDQKKRVKLAQGLWLMNWLSVLAGIVLFSLGLFLKIELRKRSDVMDNSESHFVPNSLIGVGVLSCVFNSLAGKICYDALDPAKYAKWKPWLKLYLAVCVFFNVILFLVALCCFLLRGSLESTLAYGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLNYYSSLMNSMGVVTLLIWLFEVSITAGLRFLHTALESVSNPEDPECESEGWLLENSVSETWKAFLESFKKLGKSNQVEAEAADAGQAPEAG