wanglab/gogpt-training-data huggingface dataset:
Protein: Plasmepsin X (PM X) (EC 3.4.23.-) (Plasmepsin 10) (W7JWW5)
Organism: Plasmodium falciparum (isolate NF54)
Function: During the asexual blood stage, processes key proteins essential for merozoite egress and invasion of host erythrocytes. Cleaves and activates proteases SUB1 and SUB2. May process members of the EBL and Rh protein families (By similarity). Also cleaves apical membrane protein AMA1 (By similarity). During the mosquito vector stage and probably in ookinetes, cleaves CelTOS (By similarity).
Subcellular location: Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:29074774}. Note=In schizonts, localizes to exonemes which are secretory vesicles that discharge their content during egress into the parasitophorous vacuole. {ECO:0000269|PubMed:29074774}.
Interaction partners:
Sequence:
MKRISPLNTLFYLSLFFSYTFKGLKCTRIYKIGTKALPCSECHDVFDCTGCLFEEKESSHVIPLKLNKKNPNDHKKLQKHHESLKLGDVKYYVNRGEGISGSLGTSSGNTLDDMDLINEEINKKRTNAQLDEKNFLDFTTYNKNKAQDISDHLSDIQKHVYEQDAQKGNKNFTNNENNSDNENNSDNENNSDNENNLDNENNLDNENNSDNSSIEKNFIALENKNATVEQTKENIFLVPLKHLRDSQFVGELLVGTPPQTVYPIFDTGSTNVWVVTTACEEESCKKVRRYDPNKSKTFRRSFIEKNLHIVFGSGSISGSVGTDTFMLGKHLVRNQTFGLVESESNNNKNGGDNIFDYISFEGIVGLGFPGMLSAGNIPFFDNLLKQNPNVDPQFSFYISPYDGKSTLIIGGISKSFYEGDIYMLPVLKESYWEVKLDELYIGKERICCDEESYVIFDTGTSYNTMPSSQMKTFLNLIHSTACTEQNYKDILKSYPIIKYVFGELIIELHPEEYMILNDDVCMPAYMQIDVPSERNHAYLLGSLSFMRNFFTVFVRGTESRPSMVGVARAKSKN
Protein: Nuclear fallout, isoform J (Nuclear fallout, isoform K) (M9ND89)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Midbody {ECO:0000256|ARBA:ARBA00004214}. Recycling endosome membrane {ECO:0000256|ARBA:ARBA00004654}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004654}.
Interaction partners:
- Rab11
- Homeobox protein goosecoid
- LP16520p
- Discontinuous actin hexagon
- Phosphatidylinositol 4-kinase beta
- Rab11 interacting protein, isoform A
- ADP-ribosylation factor 6
- Exocyst complex component 6
Sequence:
MSSQPASQPDSIDLAYDMWAGQFEFVGPTNQQSNKNSNNNNNNSNLNNNKCRIGAQQNRKLSTDSLEDLNLSFNTSASQNPLSNAYSLGVTGGAGSDYCGFGKHPPILIDQETFLSLNPADFEDIVPSNSEPNSLVFIENKLETNNNSLESNNNHINNNNNNKIYNLENLTSKFNNKTNNTNTNGFKLENLKNFKNKLLCDFEDTNSGGGGGGGSGGSGPVGMMNGALSAEICDNLNEQLELLQRKVDDLSDTQNIAEDRTTRTKTEYAVLQARYHMLEEQYRESELRAEERLAEEQKRHREILARVEREASLQNENCQMKIRATEIEATALREEAARLRVLCDKQANDLHRTEEQLELARDQIGVLQQEHEEQAQALRRHEQEKKSTEELMLELGRELQRAREESGARAMPTTSPESIRLEELHQELEEMRQKNRTLEEQNEELQATMLTNQATMLTNGVEQGRHLLNGTLNSLAQELEEMSQAQDSVDSATLASLSQLQQAFQEKEDENVRLKHYIDTILLNIVENYPQLLEVKPMERK
Protein: Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Rotamase D) (Q6DGG0)
Organism: Rattus norvegicus (Rat)
Function: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity region. Involved in regulation of UV radiation-induced apoptosis.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q08752}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q08752}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q08752}.
Interaction partners:
- Non-selective voltage-gated ion channel VDAC1
- ADP/ATP translocase 1
- Non-selective voltage-gated ion channel VDAC3
- Non-selective voltage-gated ion channel VDAC2
- ADP/ATP translocase 2
- ADP/ATP translocase
- Peptidyl-prolyl cis-trans isomerase F, mitochondrial
- Prostaglandin E synthase 3
- Stress-induced-phosphoprotein 1
- Heat shock protein HSP 90-beta
Sequence:
MSHPSPAGKPSNSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGTGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARMLENVEVNGEKPAKLCVIAECGELKEGDEWGIFPKDGSGDSHPDFPEDADIDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYAKVLRYLDSSKAVIEKADVSRLQPIALSCVLNIGACKLKMSNWQGAIDSCLEALEMDPSNTKALYRKAQGWQGLKEYDQALADLKKAQEIAPGDKAIQAELLKVKQMIKAQKDKEKAVYAKMFA
Protein: Sorcin (A0A8I6AU02)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
Sequence:
MEIYFGPSLQLLMSKEQEWKSLCGGAPGGPVFPGHTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFSEFRELWTVLSGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQTVNSVAKRYSTSGKITFDDYIACCVKLRALTDSFRRRDSGQQGVVNFSYDDFIQCVMTV
Protein: Pentatricopeptide repeat-containing protein At1g52620 (Q9SSR4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Putative F-box/LRR-repeat protein At5g02700
- At2g18890
Sequence:
MSKTLLSRIKPLSNPHASNSFRSHLPITPRIKKLVSDTVSILKTQQNWSQILDDCFADEEVRFVDISPFVFDRIQDVEIGVKLFDWLSSEKKDEFFSNGFACSSFLKLLARYRIFNEIEDVLGNLRNENVKLTHEALSHVLHAYAESGSLSKAVEIYDYVVELYDSVPDVIACNSLLSLLVKSRRLGDARKVYDEMCDRGDSVDNYSTCILVKGMCNEGKVEVGRKLIEGRWGKGCIPNIVFYNTIIGGYCKLGDIENAYLVFKELKLKGFMPTLETFGTMINGFCKEGDFVASDRLLSEVKERGLRVSVWFLNNIIDAKYRHGYKVDPAESIGWIIANDCKPDVATYNILINRLCKEGKKEVAVGFLDEASKKGLIPNNLSYAPLIQAYCKSKEYDIASKLLLQMAERGCKPDIVTYGILIHGLVVSGHMDDAVNMKVKLIDRGVSPDAAIYNMLMSGLCKTGRFLPAKLLFSEMLDRNILPDAYVYATLIDGFIRSGDFDEARKVFSLSVEKGVKVDVVHHNAMIKGFCRSGMLDEALACMNRMNEEHLVPDKFTYSTIIDGYVKQQDMATAIKIFRYMEKNKCKPNVVTYTSLINGFCCQGDFKMAEETFKEMQLRDLVPNVVTYTTLIRSLAKESSTLEKAVYYWELMMTNKCVPNEVTFNCLLQGFVKKTSGKVLAEPDGSNHGQSSLFSEFFHRMKSDGWSDHAAAYNSALVCLCVHGMVKTACMFQDKMVKKGFSPDPVSFAAILHGFCVVGNSKQWRNMDFCNLGEKGLEVAVRYSQVLEQHLPQPVICEASTILHAMVEKADTKEPVESP
Protein: CG1558-RA protein (Kinetochore Mis12-Ndc80 network component 1, isoform A) (Kinetochore Mis12-Ndc80 network component 1, isoform B) (RE03006p) (Q9VYX4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Nnf1a
- Nuf2
- Kinetochore protein Spc25
- Mis12
- Nnf1b
- HDC12388
- Kinetochore protein NDC80
- Centromeric protein-C, isoform A
- Spc105-related, isoform B
Sequence:
MEPAESPEKLMKFVRRSDVLEYVGNTSAVDLSSGDLSDIDLKDVPAQLEATLKPRRYEASTLFNIDLDDIWDPSCQEDEVQQYKERAQKEQQKFFDFVMHAALDTDNRKVSFKPNKEQQRYLDQGPNLQNFVRSSLAFTNAAIRFQAEHEDMMELQCNMDDHYLFMRNTMINNAIHQNMANQR
Protein: Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) (Q01662)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Plays the major role in N-terminal methionine removal. Less efficient when the second residue is Val.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03174}.
Interaction partners:
- Methionine aminopeptidase 2
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS3
- Zinc-regulated GTPase metalloprotein activator 1
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL29A
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein uL24A
- Large ribosomal subunit protein uL24B
- Guanine nucleotide-binding protein alpha-1 subunit
Sequence:
MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYKAHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGENISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILTARNKKSPGGPRQRIK
Protein: Ubiquitin ligase-binding protein BUL2 (Q03758)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of a RSP5 ubiquitin ligase complex which specifies polyubiquitination and intracellular trafficking of the general amino acid permease GAP1 as well as other permeases such as PMA1. The RSP5-BUL1/2 complex is also necessary for the heat-shock element (HSE)-mediated gene expression, nitrogen starvation GLN3-dependent transcription and pressure-induced differential regulation of the 2 tryptophan permeases TAT1 and TAT2.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- E3 ubiquitin-protein ligase RSP5
- Nitrogen permease reactivator protein
- General amino-acid permease GAP1
- Arrestin-related trafficking adapter 3
- Arrestin-related trafficking adapter 6
- Protein ARG5,6
- Ubiquitin ligase-binding protein BUL1
- Protein ROD1
- Protein LST4
- Putative lipase ROG1
Sequence:
MTFTFSTSSRKNGRPPLKSVSTEDNIHLLRKRRQQQLSSNSTDNSLHPNSGQTPRASDSQDDDIRSASTTNLDRLRQEREENSLEMDCTQSRLSHRANMLVDVLPSFEMYNALHRHIPQGNVDPDRHDFPPSYQEVRTQRMTILPSNDNSVERSQLTAVPGSENACNNATAHSLTNLHPLQTQHLTINSTRSGGQSLHSSSDTNISQIPFEDDLNDSDNIFIDKLYTLPKLSTPIEIDIRITKTASIPHERPEEQSILKEYTSGDIIHGYCLIENRSSQPLKFEMFYVTLEAYISVIDRQKGKRTLKRFLRMVDLSASWSYTNITPSTGINIVPGERDFDDAIIGLSNSRELKPNTKYKKFFMFKLPTQLLDVTCKQEQFSHCLLPPSFGIDKYKNNCKYSGIKVNSVLGCGHLGTKGSPILTLDMADDNLSINYTIDAKIVGKDKRTSKLNIMKEKEYNLRVMPFPFAGVTNQQNEKTCLRQLKNLESLIEDRFEALNKIFKKLELNEAISNVDIHDTDISGTLDGNEDLDSDEILRRKLDQLHINNRIDDTASQSPSYDSKNMAPKENLVETELRYKFKNKNKSNSSLFSHFLSSSETGSSSTGPHVYNSGLIVLSVKKPQSTLPYWSPSLLRKTNKFEAKSEQEKENWQRLMGMLPEGVKTPLTKLDVHLTCIQSNNSAGHKPPEISSVTTEFVVITAKSDNSIPIKFCTELLMNENRLNKLKTKFLTYQKKVHEYRKKFEENHAKLNELYNRNRDHFTPKELLFTNFISDQINNDIDSLAGLKVNIIDLHDIFKKQIHTFEEENEDIISKKGSSNPPSASSSNNNFLQATFSNGASTATKFTQQIVHEWEKVKPLQYKRDVTVNLKLNPNIKETLVPNLETCLCCRFYCVRVNIKFDNHLGSMKVDIPVDVKKLQI
Protein: Egg-lysin (Sperm-lysin) (P04552)
Organism: Haliotis rufescens (California red abalone)
Function: Creates a 3 um hole in the egg vitelline layer through which the sperm passes. Does not have enzyme activity. Species-specific interaction between the sperm protein lysin and the egg protein VERL exposes a basic surface on lysin that may dissociate the egg vitelline layer via electrostatic repulsion. Plays a role in ensuring species-specific fertilization.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome lumen {ECO:0000269|PubMed:7106382}.
Interaction partners:
Sequence:
MKLLVLCIFAMMATLAMSRSWHYVEPKFLNKAFEVALKVQIIAGFDRGLVKWLRVHGRTLSTVQKKALYFVNRRYMQTHWANYMLWINKKIDALGRTPVVGDYTRLGAEIGRRIDMAYFYDFLKDKNMIPKYLPYMEEINRMRPADVPVKYMGK
Protein: 3-dehydroquinate synthase, chloroplastic (EC 4.2.3.4) (Q8VYV7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the second step in the shikimate pathway.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic
- Phospho-2-dehydro-3-deoxyheptonate aldolase 2, chloroplastic
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- Phospho-2-dehydro-3-deoxyheptonate aldolase 1, chloroplastic
- 3-phosphoshikimate 1-carboxyvinyltransferase, chloroplastic
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Shikimate kinase 2, chloroplastic
- Shikimate kinase 1, chloroplastic
- Chorismate mutase 1, chloroplastic
- Chorismate mutase 2
Sequence:
MAANTISLSNVAASKNLNSFQSRAFIAPPTIFFPVASAKSKPGELSLSSTTLSRSRVRAGASQLMNEPLNDQRSISSPTVVEVDLGDRSYPIYIGAGLLDHSELLQRHVHGKRVLVVTNDRVAPLYLDKTIDALTRGNPNVTVESVILPDGEKYKDMDTLMKVFDKAIESRLDRRCTFVALGGGVIGDMCGYAAASYLRGVNFIQIPTTVMAQVDSSVGGKTGINHRLGKNLIGAFYQPQCVLVDTDTLNTLPDREMASGLAEVIKYGLIRDAEFFEWQEKNIEALLARDPAALAFAIKRSCENKADVVSQDEKESGLRATLNLGHTFGHAIETGFGYGEWLHGEAVAAGTVMAVDMSYRLGWIDESIVKRVNKILVRAKLPTTPPESMTVSMFKSIMAVDKKVADGLLRLILLKGPLGNCVFTGDYDREALDATLRAFSKS
Protein: Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein) (Q12851)
Organism: Homo sapiens (Human)
Function: Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extent of the p38 MAPKs signaling pathway. Required for the efficient activation of JNKs by TRAF6-dependent stimuli, including pathogen-associated molecular patterns (PAMPs) such as polyinosine-polycytidine (poly(IC)), lipopolysaccharides (LPS), lipid A, peptidoglycan (PGN), or bacterial flagellin. To a lesser degree, IL-1 and engagement of CD40 also stimulate MAP4K2-mediated JNKs activation. The requirement for MAP4K2/GCK is most pronounced for LPS signaling, and extends to LPS stimulation of c-Jun phosphorylation and induction of IL-8. Enhances MAP3K1 oligomerization, which may relieve N-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. Mediates also the SAP/JNK signaling pathway and the p38 MAPKs signaling pathway through activation of the MAP3Ks MAP3K10/MLK2 and MAP3K11/MLK3. May play a role in the regulation of vesicle targeting or fusion. regulation of vesicle targeting or fusion.
Subcellular location: Cytoplasm {ECO:0000250}. Basolateral cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- TNF receptor-associated factor 2
- Striatin-4
- Mitogen-activated protein kinase kinase kinase 1
- Programmed cell death protein 10
- PHD finger protein 12
- Ras-related protein Rab-8A
- Striatin
- Striatin-interacting protein 1
Sequence:
MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDPHLGTPSPEDCELETYDMFPDTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEPLSSPPGTLPPPPSGPNSSPLLPTAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNGCPLRIHAAVTWIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGATFLLAALPTSLLLLQWYEPLQKFLLLKNFSSPLPSPAGMLEPLVLDGKELPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTILVSFERCVRIVNMQGEPTATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILESIPTDNPEAHSNLYILTGHQSTY
Protein: Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-) (Q54PU2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03149}.
Interaction partners:
- Probable asparagine--tRNA ligase, mitochondrial
- Probable glutamine--tRNA ligase
- Asparagine--tRNA ligase, cytoplasmic
- Glutamyl-tRNA
- Glutamyl-tRNA
Sequence:
MLSIPEDKVEQYCDDLGGFLNSVESIQSVNTENVRPLHSILEDTQLTLHFEQTTVNQDHEHILDHSNNVQGGFFTVPKQISSHTNSQKSNKNNSIDDEF
Protein: Alpha carbonic anhydrase 5 (AtaCA5) (AtalphaCA5) (EC 4.2.1.1) (Alpha carbonate dehydratase 5) (F4HUC4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Reversible hydration of carbon dioxide.
Subcellular location: Plastid, chloroplast stroma {ECO:0000250}. Note=Targeted to the chloroplast via a protein-targeting pathway that uses the secretory system. {ECO:0000250}.
Interaction partners:
- Cyanate hydratase
- Calcium-transporting ATPase 1
- ATPase 6, plasma membrane-type
- ATPase 9, plasma membrane-type
- Ribosome production factor 2 homolog
- ATPase 8, plasma membrane-type
- Large ribosomal subunit protein uL18y
Sequence:
MKIPSIGYVFFLIFISITIVSSSPDHGEVEDETQFNYEKKGEKGPENWGRLKPEWAMCGKGNMQSPIDLTDKRVLIDHNLGYLRSQYLPSNATIKNRGHDIMMKFEGGNAGLGITINGTEYKLQQIHWHSPSEHTLNGKRFVLEEHMVHQSKDGRNAVVAFFYKLGKPDYFLLTLERYLKRITDTHESQEFVEMVHPRTFGFESKHYYRFIGSLTTPPCSENVIWTISKEMRTVTLKQLIMLRVTVHDQSNSNARPLQRKNERPVALYIPTWHSKLY
Protein: CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei) (Tyrosine kinase-associated leucine zipper protein LAZip) (Q91ZR3)
Organism: Mus musculus (Mouse)
Function: Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9NS37}. Note=Colocalizes in promyelocytic leukemia protein nuclear bodies (PML-NB) with CREB3 and HCFC1. {ECO:0000250|UniProtKB:Q9NS37}.
Interaction partners:
- Polynucleotide 5'-hydroxyl-kinase NOL9
Sequence:
MRHSLTKLLAASGRDFPSRRDSREPPATRAPPREPSGAAAGAETPRPGSPDREQPHGDGDGGEPEARSGSRGSVAVRAPAPSPLKMEEEEEDAIAMVPKEEPEDMDFLSGLELADLLDPRQPDWHLEPGLSSPGPLSSSGGGSESGGLLRGDDDDDTAAAEMQRFSDLLQRLLNGIGGCSSGGDRGGGEKRRRKSPGAGGGGANDGNQAATKSPRKAAAAAARLNRLKKKEYVMGLESRVRGLAAENQELRAENRELGKRVQALQEESRYLRAVLANETGLARLLSRLSGVGLRLTTSLFRDSPAGDHDYALPVGKQPPEPREEDDAAGGVCLHVDKDKVSVEFCSACARKASSSLKM
Protein: Mitochondrial GTP/GDP carrier protein 1 (P38988)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mitochondrial GTP/GDP transporter required for GTP uptake and GDP exit from mitochondria. Involved in mitochondrial iron transport and essential for mitochondrial genome maintenance.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:14576278}; Multi-pass membrane protein {ECO:0000269|PubMed:14576278}.
Interaction partners:
- Citrate/oxoglutarate carrier protein
- Mitochondrial pyrimidine nucleotide transporter RIM2
Sequence:
MPHTDKKQSGLARLLGSASAGIMEIAVFHPVDTISKRLMSNHTKITSGQELNRVIFRDHFSEPLGKRLFTLFPGLGYAASYKVLQRVYKYGGQPFANEFLNKHYKKDFDNLFGEKTGKAMRSAAAGSLIGIGEIVLLPLDVLKIKRQTNPESFKGRGFIKILRDEGLFNLYRGWGWTAARNAPGSFALFGGNAFAKEYILGLKDYSQATWSQNFISSIVGACSSLIVSAPLDVIKTRIQNRNFDNPESGLRIVKNTLKNEGVTAFFKGLTPKLLTTGPKLVFSFALAQSLIPRFDNLLSK
Protein: UPF0057 membrane protein YqaE (P0AE42)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- NH
Sequence:
MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIHAFWVQTRD
Protein: Microtubule-associated protein 1B (B2ZZ14)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Gigaxonin.
- Fragile X mental retardation, autosomal homolog 2.
- Fragile X mental retardation, autosomal homolog 1.
- FMRP translational regulator 1.
Sequence:
MATLVDTAETPAPFGGVGSLRSTASPTASTQHFDEGKYYLLVVIGELVTDEHLKCAIADIEKGIRSWDTNLIDCNLDQELKLFVSRHSARFSADVRGQKILHHKSNVLETVVLINPSDEAVSTEVRLMVSDTAHHKLLVLAGQCFENTGELILQSGSFSLSSFIDIFTDQEIGELLSTVHPANKASLTLFCPEHGDWKNSNLDKHNLQDFIYMKLNSPTILPEMEGLSEFTEYLSESVEISSPFDMLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSDRKSCFWKLVRHLDRVDSVLLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTANSDWTKNMISPDIGVMFANMPQNLENLEPNYRIRRNAEEAAFTLQYLNKLSLKPEPLHRSIGNTVEPIILFQKMGVGKLEMYVLNPAKNSKELQFFLKEWSGSDKDKATILLPNGKESELPVSYLSSISSLIVWHPANPSEKIVRVLFPGNSTQNHILEGLEKLKHLDFLKYPVITQNELNLNLAPTLKQAKMKHKTDSKESLKSTSKPSPTKNLHKESREETTEKLKTVSKTEPAEKQEPTQKIEKKEKTLVKKVKAGEKDIKSKVEQTHKTDTPEKKKVEIKPKTIKKESKKSVEKTETVKTEKNVPKKEDKVKKEDKVKKEEVKKEIKRRDVRKDSLLKESRKDEKKESLKDSKEPMKDLRKTGSLKKNAPSTPDVKKPAPKPKVAARGKSPGSPARSKDKAKSKPTKKDAGESVAAPSVSGATVEEPTVEDSATDVLEAERSLMSSPEDLTKDFEALKAEEMAEDDEVLSQTKIDDSNQEEVIRHEEITHCKESPEAAESLDEGIATTEAEEECGGTPGELEPNQKSNGTSEKFEDEGTGLEESSELGDYEEKGETEEVDEQDRAISTLKDEQAELETKEGANYGTDEPEYLDKETKLQCFDVTTPPKLTAPLSPADSVHDETLPAGSESEAASDDENRDEPPEEYTTSGHTQSTIEISSVPTPMDEMSTPRDVMSDETTNDESDSPSQDFVRYGITTEHERKKLSPLQDVPELDHSKSDATEGHDYHVSASTISPPSSLEEDKSVKDFSVKDTFSFDSSRLTTTTNLPFVRSPSVDQNVNIDLVHAGVSSPIELGTTLAGISKGLESYSPDEKTLEGPLSPQSSGHTPFYQSPVEEKAGTLPSEKTSEAQGPVIVDITSDKEYSPREASPIDEAVPVSQPGKKQSPIYEAHLSTNFEFDSKLPSQTDNSDKKIATDDNSSVISATSLPPSKIESLSETKHFTTFKEDSKMSISEGTTSDKSGTPVDEVVADDTFSHIASASTASLATSSLPEPTTDDVSPSLHAEVGSPHSTEVDDSFSVSVVQTPTTMQEAEVSPSKEDSPRPMSISPDVSPKTAKLRMPEQETKSPEKLSAGCEQESPEHSFALDFSKQSPDHPSVGGMQSTATENGPTEVDDSPLDEVGSMGEQHRPGEAGDKAMFFKDSDSTQAASASPSDASQSTPSVTTPCQIAEPREVSPDLDNLSESVTPKQSPSKQSPLSLDSSLVLGRPSISHEEVNKGKLSPNSFYEESAMDKSEDTQNLERTPPKASSPLSPTESLCFSQKTEELKLGSETTTFTGSKSPTSPKMSPPAQLSPSSTQTDTLDKFSTSSSSYSYSCQNVESTQICDGGSIGPETSKACHSQSRAEVDLCLVTSCEYRHPKTELSPSFINPSPLEYFMTEEPNLGEEKPLAKSGEGPPPPEEKQQTKQCEETPPTSVSESAPSQTDSDVPPGTEECPSITADANIDSEDDSETLPTDRTITYRHADPPPVTPRDPAPTPPHPDACMVDPEVLKAEEASGKPKKNISSKTKPSATKSLSKTSAIKESKVSSPKKSTEDKDAKNATNTSASRGVKNSTSGSTKSSGGTSVPNCPTMYMDLVYIPNHCNAKNVDAEFFKRIRSSYYVVSGNDPTAQEPSKAVLDALLEGKSQWGNNMQVTLIPTHDTEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIEL
Protein: Uncharacterized protein (Q389P8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPSSVALRVRLSIANPAVERLLVCIGTLNDEQGSEARGALGRLVARKILETCAPSPSDVQNPDENRIQARDAKGRTRERYAFRQYGPFARHTCSHSGSRFRRPCRNAQTWDSERVSDYMGVWCDRLLLGEHNNPRRCALLEPRVPVVMVGESLERVLLAHRGLRGSDILFIFGSPCFPFGATRLISFSDALLDPLCISYPSRHQLVGTVLHCLECESSIPSALVVGLGSTHGLRTAFEPEEKVLIESRIVPLLGFVSALWTVDPLKASEYLQSNPQNNARLWGTMQSSMLSTRDAALLRAFESGQPLDARLSQQHTAYLAETLLDRLFPQSGQ
Protein: Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1) (allergen Asp f 6) (Q92450)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:Q9UQX0}.
Interaction partners:
- Superoxide dismutase
- Fe superoxide dismutase, putative
- Superoxide dismutase
- Allergen Asp f 4
- Peroxiredoxin Asp f3
- Ribonuclease mitogillin
- Rhodanese domain protein
- 50S ribosomal subunit protein L15
- Small ribosomal subunit protein bS18m
Sequence:
MSQQYTLPPLPYPYDALQPYISQQIMELHHKKHHQTYVNGLNAALEAQKKAAEANDVPKLVSVQQAIKFNGGGHINHSLFWKNLAPEKSGGGKIDQAPVLKAAIEQRWGSFDKFKDAFNTTLLGIQGSGWGWLVTDGPKGKLDITTTHDQDPVTGAAPVFGVDMWEHAYYLQYLNDKASYAKGIWNVINWAEAENRYIAGDKGGHPFMKL
Protein: Myb family transcription factor EFM (MYB-domain transcription factor HHO4) (Protein EARLY FLOWERING MYB) (Protein HRS1 HOMOLOG 4) (Q9ZQ85)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor acting as a flowering repressor, directly repressing FT expression in a dosage-dependent manner in the leaf vasculature.
Subcellular location: Nucleus {ECO:0000269|PubMed:25132385}.
Interaction partners:
- Actin cytoskeleton-regulatory complex pan-like protein
- Polynucleotide 5'-hydroxyl-kinase NOL9
- GATA transcription factor 7
- Aspartic proteinase PCS1
Sequence:
MASSSELSLDCKPQSYSMLLKSFGDNFQSDPTTHKLEDLLSRLEQERLKIDAFKRELPLCMQLLNNAVEVYKQQLEAYRANSNNNNQSVGTRPVLEEFIPLRNQPEKTNNKGSNWMTTAQLWSQSETKPKNIDSTTDQSLPKDEINSSPKLGHFDAKQRNGSGAFLPFSKEQSLPELALSTEVKRVSPTNEHTNGQDGNDESMINNDNNYNNNNNNNSNSNGVSSTTSQSNRKARRCWSPDLHRRFVQALQMLGGSQVATPKQIRELMKVDGLTNDEVKSHLQKYRLHTRRPSPSPQTSGGPGPHLVVLGGIWVPPEYTSAHGGTPTLYHHQVHHHHTNTAGPPPPHFCSSQEFYTTPPPPQPLHHHHFQTFNGSSGGTASTDSTHHQVTDSPTVEGKSPESGGGERKGLAALREECEDHSNINGSEITLKF