wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)] (P63053)
Organism: Sus scrofa (Pig)
Function: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Subcellular location: [Ubiquitin]: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.; SUBCELLULAR LOCATION: [Large ribosomal subunit protein eL40]: Cytoplasm {ECO:0000250|UniProtKB:P62984}.
Interaction partners:
- Large ribosomal subunit protein eL32
- Polyubiquitin-C
- Ubiquitin-ribosomal protein eS31 fusion protein
- Proteasomal ubiquitin receptor ADRM1
- Large ribosomal subunit protein uL3
- Ubiquitin B
- Ribosomal protein L26
- Large ribosomal subunit protein uL16
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein eL42
Sequence:
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK
Protein: Ras-related protein Rab-2A (EC 3.6.5.2) (P53994)
Organism: Mus musculus (Mouse)
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi.
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor {ECO:0000250|UniProtKB:P61019}; Cytoplasmic side {ECO:0000305}. Melanosome {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000305}; Lipid-anchor {ECO:0000250|UniProtKB:P61019}; Cytoplasmic side {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:34714330}; Lipid-anchor {ECO:0000250|UniProtKB:P61019}; Cytoplasmic side {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:34714330}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:28063257}; Lipid-anchor {ECO:0000250|UniProtKB:P61019}; Cytoplasmic side {ECO:0000305}. Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid. {ECO:0000269|PubMed:34714330}.
Interaction partners:
- TBC1 domain family member 1
- Golgi reassembly-stacking protein 2
- Solute carrier family 2, facilitated glucose transporter member 4
- Golgin-45
- Vam6/Vps39-like protein
- Islet cell autoantigen 1
- Glyceraldehyde-3-phosphate dehydrogenase
- Mitogen-activated protein kinase 3
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNASHGSNQGGQQAGGGCC
Protein: Pre-mRNA processing factor 3 (A0A8I6GK69)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MALSKRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPFLDDSTLRFVDKLFEAVEEGRSSRHSKSSSDRSRKRELKEFQEALAPG
Protein: Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23) (CDK-activating kinase 1-At) (CAK1-At) (O80345)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: CDK-activating kinase that modulates CDKD-2 and CDKD-3 activities by phosphorylation of the T-loop. Activates CDKD-2 C-terminal domain (CTD) kinase activity. Activates CDKA-1 probably by phosphorylation. Posseses a CDK kinase activity independently of association with cyclin CYCH1-1. Phosphorylates the CTD of the large subunit of RNA polymerase II.
Interaction partners:
- Cyclin-H1-1
- Retinoblastoma-related protein 1
- Cyclin-dependent kinase D-2
- Cyclin-dependent kinase D-3
- Dual specificity phosphatase Cdc25
- Cyclin-dependent kinases regulatory subunit 1
- Cyclin-dependent kinases regulatory subunit 2
- Wee1-like protein kinase
- Serine/threonine-protein kinase ATR
- Origin of replication complex subunit 2
Sequence:
MDKQPATSWSIHTRPEIIAKYEIFERVGSGAYADVYRARRLSDGLIVALKEIFDYQSAFREIDALTILNGSPNVVVMHEYFWREEENAVLVLEFLRSDLAAVIRDGKRKKKVEGGDGFSVGEIKRWMIQILTGVDACHRNLIVHRDLKPGNMLISDDGVLKLADFGQARILMEHDIVASDENQQAYKLEDKDGETSEPPEVIPDYENSPRQGSDGQEREAMSKDEYFRQVEELKAKQVVRDDTDKDSNVHDGDISCLATCTVSEMDDDLGRNSFSYDADEAVDDTQGLMTSCVGTRWFRPPELLYGSTMYGLEVDLWSLGCVFAELLSLEPLFPGISDIDQISRVTNVLGNLNEEVWPGCVDLPDYKSISFAKVESPLGIEGCLPNHSGDVISLLKKLICYDPASRATTMEMLNDKYLSEEPLPVPVSELYVPPTMSGPDEDSPRKWNDYREMDSDSDFDGFGPMNVKPTSSGFTIEFP
Protein: Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CPB-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha) (P14668)
Organism: Rattus norvegicus (Rat)
Function: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Interaction partners:
- Caspase-3
- Apoptosis regulator Bcl-2
- Caspase-8
- Cholecystokinin
- Actin, cytoplasmic 1
- Glyceraldehyde-3-phosphate dehydrogenase
- Cellular tumor antigen p53
- Caspase-9
- T-cell surface glycoprotein CD4
- Peroxidasin
Sequence:
MALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
Protein: Serine/threonine protein phosphatase 2A regulatory subunit (A0A0B4KHB9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDNEALDPTIKSSTSAATPTAAASETTTTAASSVVETTTTIAAATASAAESKNETTATNNNSNTSGSISSSSSNNIVIPASATNGIKESNSNLSTTTTAAAVAAATTVEGVAPAITSTIVVTGGTPPLSSLAAQLRRQGFAQSKANKLKDNTPPYDAPPPTPISKVLNITGTPIVRKEKRQTSARYNASKNCELTALIPLNEKTAASEREELFIQKIQQCCTLFDFSEPLSDLKFKEVKRAALHEMVDFLTNQNGVITEVIYPEAINMFAVNLFRTLPPSSNPNGAEFDPEEDEPTLESSWPHLQLVYELFLRFLESPDFQPSMAKRFIDHQFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNVFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQLTYCVVQFLEKDPSLSEAVIKSLLKFWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIAKCVSSPHFQVAERALYYWNNEYIMSLITDNSAVILPIMFPALNRNSKTHWNKTIHGLIYNALKLFMEIDQRLFDECSKNYKQEKQMEREKLSQREELWQQVESLAKTNPEWTKARRFNDCLPVSDSRALCDQYSENSDSAYDQSEQRARQPPPPLPPQKQAHQEPREIRGERNKDKPLLRRKSDLPSDSGTVKALNEHKRTDEYLTTPPPDGNY
Protein: Trivet, isoform F (A0A0B4KH70)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLAMPTLMMPATAQMTLSAAHGKPYETKLLAIHQTHLQQQQQQQAPAPPQQQQQVQQSQQQAPNGKQQSQQMTIVTTQQQQQQQHPQSQSPHQQQQSQQQAAAAAAAAAAAAHHQQQQAVAAAVCAAQQQAVVVQQQQQQQYQIHSQQQSPQQQQVLCISPKQEQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVTPAAASAAAVQNQFLQGIQGYHFGQYGGYQQGYMGMGVQIPATWQGVTQAQISPAQQLATGVAGTAIPQAAGVVAYPIQQFQVSPQAQ
Protein: E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM9) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9) (Q91ZY8)
Organism: Rattus norvegicus (Rat)
Function: E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions (By similarity). May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000269|PubMed:11524423}. Synapse {ECO:0000269|PubMed:11524423}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11524423}. Cytoplasm {ECO:0000250|UniProtKB:Q9C026}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9C026}. Note=Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (By similarity). Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (PubMed:11524423). {ECO:0000250|UniProtKB:Q9C026, ECO:0000269|PubMed:11524423}.
Interaction partners:
- Netrin receptor DCC
- Beta-transducin repeat containing E3 ubiquitin protein ligase
- Vasodilator-stimulated phosphoprotein
Sequence:
MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSRRASGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPPTHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRTMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVAADGYILELDDGSGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIIFSNDNLTVTCSSYDDRVVLGKTGFSKGVHYWELTIDRYDNHPDPAFGVARIDVMKDMMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKTLTFFVNNEQQGPIAFENVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
Protein: Eomesodermin (P79944)
Organism: Xenopus laevis (African clawed frog)
Function: Functions as a transcriptional activator playing a crucial role during development. Functions in gastrulation, regulating mesoderm differentiation. Activates wnt8, t/bra, chrd and mix-A/mix.1 expression.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MVPGAWHSLLFTTSSASEKEENRSQRMQLGEQLLNSSTPNLPHTFYPLTGDPSSAVHSPSLEFSVGHKGQQHKKYSSGSSRGLQLDSPREAGSSSTMLSETGEGFSVAKTLPDNVRKGSPSAEEELNTAVPTSAPRYLDGSLQAASERYYLQPQGQQLQQTTTELGSPCSIFPYAPPQHSAVYPAGGAARYPPYGSMLPPAGFSPPVCPSRPQYSSGYQYSQAPGTMYSPYPPAGTGSGLSALGLPGGGAGVRAQVFLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNITGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKVYVHPESPNTGAHWMRQEISFGKLKLTNNKGANNNSTQMIVLQSLHKYQPRLHIVEVSEDGVEDLNDSAKNQTFTFPENQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASESDRLTPSPADSPRSHQIVPGTRYSVQPFFQDQFVNNLPPARYYSGERTVPQANGLLSPQTNEEVANVPPQRWFVTPVQQAAANKLDMGAYETDYSSGSLLTYGIKSLPIQTSHPMAYYPDAAFASMAGWGSRGSTYQRKMTTSLPWSSRSSPSGFSEDLLPKDKVKEEMSSSWVETPPSIKSLDSNDSGVYTGACKRRRLSPSTSSNENSPPIKCEDIGTEDYKDATKGLGYYSFYSSS
Protein: Protein LTV1 (Low-temperature viability protein 1) (P34078)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in protein transport. Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome.
Subcellular location: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Interaction partners:
- Pre-rRNA-processing protein PNO1
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS13A
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS4B
- Small ribosomal subunit protein eS12
- Small ribosomal subunit protein uS9A
- Casein kinase I homolog HRR25
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS11B
Sequence:
MSKKFSSKNSQRYVVVHRPHDDPSFYDTDASAHVLVPVSNPNKTSPEADLRKKDVSSTKPKGRRAHVGEAALYGINFDDSEYDYTQHLKPIGLDPENSIFIASKGNEQKVEKKNIEDLFIEPKYRRDEIEKDDALPVFQRGMAKPEYLLHQQDTTDEIRGFKPDMNPALREVLEALEDEAYVVNDDVVVEDISKKTQLQGDNYGEEEKEDDIFAQLLGSGEAKDEDEFEDEFDEWDIDNVENFEDENYVKEMAQFDNIENLEDLENIDYQADVRRFQKDNSILEKHNSDDEFSNAGLDSVNPSEEEDVLGELPSIQDKSKTGKKKRKSRQKKGAMSDVSGFSMSSSAIARTETMTVLDDQYDQIINGYENYEEELEEDEEQNYQPFDMSAERSDFESMLDDFLDNYELESGGRKLAKKDKEIERLKEAADEVSKGKLSQRRNRERQEKKKLEKVTNTLSSLKF
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q9U722)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MECLSARDRHGYTPAHWIALNGXVQLMRYLIERTAPIDLPCLGTQGPRPIHWACRKGHASVVQVLLQAGVAVNAADFKGLTPLHLACMYGRTATAAYLLGMGALNNLTDINGDTALHWAAYKGHADLMRLLMYSGVELQKTDNFGSTPLHLACLSGNMTCVRLLCEKSQLDLEPRDKNGKTPIMLAQAHQHQDVVRLLYGEVKKKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWNILRRSHYCFIYWNAVMWISWAIANRRDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEGFTMLYVLGLIEAVVFCGLGWILTCTSVSASFPKILIVLTSFALADPARLHESHHKRDV
Protein: Photosystem II D2 protein (PSII D2 protein) (EC 1.10.3.9) (Photosystem Q(A) protein) (P0C435)
Organism: Oryza sativa (Rice)
Function: Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01383}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01383}.
Interaction partners:
Sequence:
MTIALGRVTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFALIGFMLRQFELARSVQLRPYNAISFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
Protein: Thioredoxin F-type, chloroplastic (Trx-F) (P09856)
Organism: Spinacia oleracea (Spinach)
Function: Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The F form is known to activate a number of enzymes of the photosynthetic carbon cycle.
Subcellular location: Plastid, chloroplast.
Interaction partners:
Sequence:
MALHLSLSHQSWTSPAHPITSSDPTRSSVPGTGLSRRVDFLGSCKINGVFVVKRKDRRRMRGGEVRASMEQALGTQEMEAIVGKVTEVNKDTFWPIVKAAGDKPVVLDMFTQWCGPCKAMAPKYEKLAEEYLDVIFLKLDCNQENKTLAKELGIRVVPTFKILKENSVVGEVTGAKYDKLLEAIQAARSS
Protein: Protein VERNALIZATION INSENSITIVE 3 (Q9FIE3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a central role in vernalization by mediating the initial transcriptional repression of the homeotic gene FLC, a floral repressor, after a cold treatment. However, due to its transient expression, it cannot maintain repression of FLC, which is then maintained by Polycomb Group complexes containing VRN2 throughout development. Required to deacetylate histones on the FLC promoter. Together with VIL1, required during vernalization for the modifications of FLC and FLM chromatin that are associated with an epigenetically silenced state (e.g. chromatin modifications, histone deacetylation, and trimethylated H3 'Lys-4' H3K4me3 and 'Lys-27' H3K27me3) and with acquisition of competence to flower.
Subcellular location: Nucleus. Nucleus speckle. Note=Probably DNA-associated; interacts directly with the FLC regulatory regions.
Interaction partners:
- Polycomb group protein VERNALIZATION 2
- VIN3-like protein 1
- Histone-lysine N-methyltransferase EZA1
- Histone-binding protein MSI1
- Polycomb group protein FERTILIZATION-INDEPENDENT ENDOSPERM
- VIN3-like protein 2
- Inactive protein FRIGIDA
- B3 domain-containing transcription factor VRN1
- Histone-lysine N-methyltransferase CLF
- MADS-box protein SOC1
Sequence:
MQAASLSKIWRFDGNVGPENMDSSSFEDNECIETCKPNVLNVSERRELIHALSNQPEEASELLNSWSRNEIMKIICAEMGKERKYTGLNKPKLIENLLNLVSRPLGETSCSDRRNSRKKEKKMIGYIICCENLACRAALGCDDTFCRRCSCCICQKFDDNKDPSLWLTCDACGSSCHLECGLKQDRYGIGSDDLDGRFYCAYCGKDNDLLGCWRKQVKVAKETRRVDVLCYRLSLGQKLLRGTTKYRNLLELMDEAVKKLEGDVGPLSGWAMKMARGIVNRLSSGVHVQKLCSQAMEALDKVVSPSESVSGQGDKMTVRVEEIQARSVTVRVDSEEPSSSTQNKITGFRLFCRKSKDEECSSQGNCVVYLPETTSAIQGLEPDTEFCLRVVSFNEEGDLDESELRFTTLKDDGDEAGDQQSPLTNSSSGLCSNPSLPEDESNNVNKSCSKGNGDKDNTEHCSAGEVESELEEERLVKRKANKIDGRDLLVTPCKRDIYKGKQGGNKRFKSRTVSLNEKPEINNAANGVGDKDLGHIVKTIRCLEEEGHIDKSFRERFLTWYSLRATHREVRVVKIFVETFMEDLSSLGQQLVDTFSESILSKRSSTNGVVPAGICLKLWH
Protein: Trypanothione synthetase (EC 6.3.1.9) (Q8IEX1)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MTKSALADTKEEPHVPFGEIQGYTPCGVPAYSNGHDGFFSGERSIDGNLFCGFKYQCVEFARRWLYEAKGLVLPDVNWAAHIFDLTEVHDASTATPVPCVKVSNGTAAKPVADSLLIYAVNEDAPWGHVAVITEVGDKWVRIADQNHRFHKWKGTYSAELLLKHEGSVWTVEDHAAEGIFVPLGWVTFPSRPNRNPKEPLVLHESLYFKQPEKPFLRRVVFTPENRKTDWLDLTNEAEAEFYKTFGKEATRGGVYESCYYLMNRELYLNCVRYGTQLHSFFLEATKQVLESDDKLRRFRIPEEYWPRIRHSWKTQPHAITGRFDFVFDENTQEFKCFEYNADSASTLLECAVIQEKWANSVGLDDNATRSSGKFMPQTLVRAWEMTGLKGRVHFLVDDDGEERYTALYVMEKAREAGIDAKLCVMFDEFHFDEKGAVVDSDGIPVTAVWKTWMWETAISDHQAAREQRGAEWKPTPKDKVRLCDILLGNNWDIRVFEPMWKLIPSNKAILPIIYNNHPDHPAILPASYELTDELRRTGYAKKPIVGRVGRNVTVTEPDGKVLAESDGNFSNRDMVYQQLFRIPKRGDYYAILGGWMLGDTYSGTGVREDKKLITGLESPFGPVRIQM
Protein: Protein ANTHESIS POMOTING FACTOR 1 (Q9LYK6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of a chromatin regulatory complex involved in regulating chromatin structure in the nucleus (By similarity). Promotes flowering under long days (LD) via the regulation of bolting.
Subcellular location: Nucleus {ECO:0000269|PubMed:27968983}.
Interaction partners:
- Flowering time control protein FY
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Cleavage and polyadenylation specificity factor subunit 2
- Protein TRAUCO
- 30-kDa cleavage and polyadenylation specificity factor 30
- Cleavage and polyadenylation specificity factor subunit 3-I
- Protein RBL
- Cleavage stimulating factor 64
- FIP1[V]-like protein
- Zinc finger CCCH domain-containing protein 65
Sequence:
MSLTELDDGLVRRMAMGAVFSDFGGKIHSVGFHRTDDLLVTSSEDDSLRLFDIANAKQLKITYHKKHGTDRVCFTHHPSSLICSSRYNLESTGESLRYLSMYDNRILRYFKGHKDRVVSLCMSPINDSFMSGSLDRSVRLWDLRVNACQGILHLRGRPAVAYDQQGLVFAIAMEGGAVKLFDSRCYDKGPFDTFLVGGDTAEVNDIKFSNDGKSMLLTTTNNNIYVLDAYRGEKKCGFSLEPSQGTPIEATFTPDGKYVLSGSGDGTLHAWNIENPSEVARWENNIGVVSCLKWAPRRAMFVAASTVLTFWIPNDGESPAPADPPTDQQQ
Protein: Inactive serine/threonine-protein kinase PLK5 (Polo-like kinase 5) (PLK-5) (Q4FZD7)
Organism: Mus musculus (Mouse)
Function: Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:20100802}. Cytoplasm {ECO:0000250}.
Interaction partners:
- Separin
- Kinesin-like protein KIF23
Sequence:
MEPRSRRRRSRQLVATFLRDPGSGRVYRRGKLIGKGAFSRCYKLTDMSTSAVFALKVVPRGGAGRLRLRGKVEREIALHSRLRHRNIVAFHAHFADRDHVYMVLEYCSRQSLAHVLKVRRTLTEPEVRYYLRGLVSGLRYLHQQRIVHRDLKPSNFFLNKNMEVKIGDLGLAARVGPAGRCHRVLCGTPNFQAPEVVSRNGHSCKSDIWALGCIMYTVLTGTPPFAAAPLSEMYQNIRDGHYLEPTHLSPSARSLIARLLAPDPAERPSLDHLLQDDFFSQGFTPERLPPHSCHSPPVFAFPPPLGRLFRKVGQLLLTQCRPPCPFTSKEASGPGEEGTEPDHMEAGNEERDPLCTEGRIHLLTLGTPRTGLAGPKGSLALQLEVATRKLFLCLDAGPMAGQDPPGEQRPVLWAPKWVDYSLKYGFGYQLSDGGSGVLFRDGSHMALRPQGGHVSYQPDQGTLWTFTLRDVPSPLRAKLAVLRLFACYMQRRLREEGTVPMPATPASPDISLLSFIADSQAMVMLFSNGTVQVSLKTSQTQLVLSGEDEDLLLTLQEPGGPAVGVSYTLDVLRSHGFTLAVHHHLRHGLHLLQSV
Protein: Synaptosomal-associated protein (O62414)
Organism: Caenorhabditis elegans
Subcellular location: Synapse, synaptosome {ECO:0000256|ARBA:ARBA00034102}.
Interaction partners:
Sequence:
MSGDDDIPEGLEAINLKMNATTDDSLESTRRMLALCEESKEAGIKTLVMLDDQGEQLERCEGALDTINQDMKEAEDHLKGMEKCCGLCVLPWNKTDDFEKTEFAKAWKKDDDGGVISDQPRITVGDSSMGPQGGYITKITNDAREDEMDENVQQVSTMVGNLRNMAIDMSTEVSNQNRQLDRIHDKAQSNEVRVESANKRAKNLITK
Protein: D-mannonate oxidoreductase (EC 1.1.1.57) (Fructuronate reductase) (P39160)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Mannonate dehydratase
- Uronate isomerase
- Starvation-sensing protein RspA
- Uxu operon transcriptional regulator
- PTS system mannitol-specific EIICBA component
- Starvation-sensing protein RspB
- 2-dehydro-3-deoxygluconokinase
- Altronate dehydratase
- Hexuronate transporter
- Exu regulon transcriptional regulator
Sequence:
MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHHLLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALHPEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKSAIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENVTFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKVGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTVTNPAYRKAAFALMMQEQAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQNGGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLSGIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL
Protein: Alpha-humulene synthase (EC 4.2.3.104) (Terpene synthase TPS-Hum) (PgTPS-Hum) (F2XF97)
Organism: Picea glauca (White spruce) (Pinus glauca)
Function: Terpene synthase (TPS) involved in the biosynthesis of sesquiterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens. Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to (1E,4E,8E)-alpha-humulene.
Interaction partners:
Sequence:
MAQISESAAIPRRTANHHGNVWDDDLILSLDSPYGAPAYYERLAKLIEEMKHLLLREMEDSNHDLIRRLQIVDTLECLGIDRHFQHEIKTAALHYVYRCWNEKGIGMGSSDSGSKDLDATALGLRALRLHRYNVSSGVLENFQDENGKFFCNLTGDKRVRSMLSLLRASEISFPGEKVMQEAKAFTREYLTQVLAGSGDVTDVDQSLLREVKYALEFPWYCSAPRWEAKSFIEIYGQNQSWLKSNINQEVLELAKLDFSILQCIHQKEIQCITRWWRDSEIAQLNFYRRRHVELYFWAVTCIFEPEFSPSRIAFAKITTVGAVLDDLYDTHGTLDELKTITEAVRRWDLSLIDDLPNNIKIACQFFFNTANELAVEVVKKQGRDMTALLKATWQRYVESYLQEAEWIETRHVPSFNEYIKNALVSSGMCIVNLIPLLLLGQLLANNIVEQILSPSKIQELSELTIRLIDDIRDFEDEKERGEIASIVECYMKDNPDSTLENALNHIKGILHVSLEELNWEFMKDDSVPLCCKKFTFNIVRGLQFLYKYGDGISISNKEVKDQIFKILVDQIPIED
Protein: Flagellum transition zone component (O76228)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MQSGVGNITTPTSPQQLVVEAPAELLETCGVQYPAAADVNEGEVVDSKALSAAPGERDVSGCGPTLLSLLYSTQKKDEVGHRAVTPMLWECNGAQKRCHSSKRDFTTCVKARKSPPPGSATGSGTGAIRDFLRPYRESHSKRFRAKVVDCRAALSVDDQIITLKNENAKYKAQLLTKDVQLKELEAALRAFRAPRVPVPSGVTEPAEVGGCYNGTDTEVARLTRENGEVWRRLQQSHAQLAVWKRDARVSKLQELKMELAVYQAQVARLVAEVPSSGGAGGAQNHPARSKLQREAETSRAKDLFIAELKERASENATALRKCMDDAMRTKSTLEQVREENELISKELCLFRKTALALTRVQEELRATQCELAEARERLQAFEQMMHTVGGPEEVKAVVKERDALLTLLKQHNAREAAYHREFFTRQREMKESMERCLQEAVQQERALAQDREMQLRRSCLMWKERCERLLPDKSFEQGRLIEGGGTVVGDEEQQTELHQLPKKIVTPFMDNSQRQRLLTKHIDDVLIVRQVSSTSAPASSSTTLSPVSGLSKLSITDTTQSQSSSHGMQVSHPGNEDASSPVKGNVMSSQKGSSGDAPVPPTERTDPDGGAVSYPASSAVISAERTSLVESSKGDIVTSISTEEGAVQLPRGLMTAGVDSSDDSGSELSDLAVGIEEGKTPSFRLHGNSDGQLIPEVVSRMPLTLRTVSSNGVPAVLTVASPPPRVSVPPAPVPRESAGSIASSENKLSDVNVAVPPPRVSVPPAPVPQESAGSIASSENKLSDVNVAVPPPRVSVPPAPVPRESAGSIASSENKLSDVNVAVPPPRVSVPPAPVPRESAGSIASSENKLSDVNVAVPPPRVSVPPATVP