wanglab/gogpt-training-data huggingface dataset:
Protein: ABC transporter ATP-binding protein ARB1 (EC 3.6.5.-) (ATP-binding cassette protein involved in ribosome biogenesis 1) (P40024)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Stimulates 40S and 60S ribosome biogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16260602}. Nucleus {ECO:0000269|PubMed:16260602}. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000269|PubMed:16260602}.
Interaction partners:
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL13A
- Large ribosomal subunit protein uL24A
- Large ribosomal subunit protein uL29A
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein uL18
- Translation initiation factor RLI1
- Large ribosomal subunit protein uL22A
- Large ribosomal subunit protein uL30B
Sequence:
MPPVSASKAKRDAKKAEREAKKAAAGKTIRKLGRKKEAAAEESEVDAAAREIKMMKLQQDKDGLSDRVVTGVLSSLETSRDIKLSSVSLLFHGKVLIQDSGLELNYGRRYGLLGENGCGKSTFLKALATREYPIPEHIDIYLLDEPAEPSELSALDYVVTEAQHELKRIEDLVEKTILEDGPESELLEPLYERMDSLDPDTFESRAAIILIGLGFNKKTILKKTKDMSGGWKMRVALAKALFVKPTLLLLDDPTAHLDLEACVWLEEYLKRFDRTLVLVSHSQDFLNGVCTNMIDMRAQKLTAYGGNYDSYHKTRSELETNQMKQYNKQQEEIQHIKKFIASAGTYANLVKQAKSRQKILDKMEADGLVQPVVPDKVFSFRFPQVERLPPPVLAFDDISFHYESNPSENLYEHLNFGVDMDSRIALVGPNGVGKSTLLKIMTGELTPQSGRVSRHTHVKLGVYSQHSQDQLDLTKSALEFVRDKYSNISQDFQFWRGQLGRYGLTGEGQTVQMATLSEGQRSRVVFALLALEQPNVLLLDEPTNGLDIPTIDSLADAINEFNGGVVVVSHDFRLLDKIAQDIFVVENKTATRWDGSILQYKNKLAKNVVL
Protein: mRNA cap guanine-N(7) methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7))-methyltransferase) (mRNA cap methyltransferase) (Q9D0L8)
Organism: Mus musculus (Mouse)
Function: Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O43148}.
Interaction partners:
- mRNA-capping enzyme
- RNA guanine-N7 methyltransferase activating subunit
- RNA guanine-7 methyltransferase activating subunit like
- Transcription elongation factor SPT5
- Eukaryotic translation initiation factor 4E
- Nuclear cap-binding protein subunit 2
- Nuclear cap-binding protein subunit 1
- Eukaryotic translation initiation factor 4E type 2
- Cap-specific mRNA
- Eukaryotic translation initiation factor 4E type 3
Sequence:
MEGSAKASVASDPESPPGGNEPAAASGQRLPENTPPCQQVDQPKMQKEFGEDLVEQNSSYVQDSPSKKRKLDVEIILEEKHSEDDGGSAKRSKLERGDVSEDEPSLGRLNQTKRKLQPQDDEVPQKLQKLEEGHSSAVAAHYNELQEVGLAKRSQSRIFYLRNFNNWIKSILIGEILEKVRQRKTRDITVLDLGCGKGGDLLKWRKGRISRLVCADIADISMKQCQQRYEDMRCRRDNEHIFSAEFITADCSKELLVEKFRDPEMYFDVCSCQFACHYSFESQVQADTMLRNACGRLNPGGYFIGTTPNSFELIRRLEASETESFGNEIYTVKFQKKGNYPLFGCKYDFNLEGVVDVPEFLVYFPLLTEMAKKYNMKLIYKKTFLEFYEEKIKNNENKMLLKRMQALEQYPAHENSKLASEKVGDYTHAAEYLKKSQVRLPLGTLSKSEWEATSIYLVFAFEKQQ
Protein: Keratin, type II cytoskeletal 80 (Cytokeratin-80) (CK-80) (Keratin-80) (K80) (Type-II keratin Kb20) (Q6KB66)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MACRSCVVGFSSLSSCEVTPVGSPRPGTSGWDSCRAPGPGFSSRSLTGCWSAGTISKVTVNPGLLVPLDVKLDPAVQQLKNQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWSFLQGQDSAIFDLGHLYEEYQGRLQEELRKVSQERGQLEANLLQVLEKVEEFRIRYEDEISKRTDMEFTFVQLKKDLDAECLHRTELETKLKSLESFVELMKTIYEQELKDLAAQVKDVSVTVGMDSRCHIDLSGIVEEVKAQYDAVAARSLEEAEAYSRSQLEEQAARSAEYGSSLQSSRSEIADLNVRIQKLRSQILSVKSHCLKLEENIKTAEEQGELAFQDAKTKLAQLEAALQQAKQDMARQLRKYQELMNVKLALDIEIATYRKLVEGEEGRMDSPSATVVSAVQSRCKTAASRSGLSKAPSRKKKGSKGPVIKITEMSEKYFSQESEVSE
Protein: At5g17690 (Q058P7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKGASGAVKKKPQVLNEAGEAETAVETVGESRKISGDGGFGSDDGGGGGGGGSGESILREIGDDRPTEDGDEEEEEDEDEDDGGDEEDEEGEGEGGQEERPKLDEGFYEIEAIRRKRVRKGKVQYLIKWRGWPETANTWEPLENLQSIADVIDAFEGSLKPGKPGRKRKRKYAGPHSQMKKKQRLTSTSHDATEKSDSSTSLNNSSLPDIPDPLDLSGSSLLNRDVEAKNAYVSNQVEANSGSVGMARQVRLIDNEKEYDPTLNELRGPVNNSNGAGCSQGGGIGSEGDNVRPNGLLKVYPKELDKNSRFIGAKRRKSGSVKRFKQDGSTSNNHTAPTDQNLTPDLTTLDSFGRIARMGNEYPGVMENCNLSQKTKIEELDITKILKPMSFTASVSDNVQEVLVTFLALRSDGKEALVDNRFLKAHNPHLLIEFYEQHLKYNRTP
Protein: Mitogen-activated protein kinase (EC 2.7.11.24) (A0A1D8PT38)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Serine/threonine-protein kinase STE7 homolog
- Transcription factor CPH1
- Cyclin-dependent protein serine/threonine kinase inhibiting protein
- Dual specificity protein tyrosine phosphatase CCP1
- Cst5p
- Guanine nucleotide-binding protein subunit alpha
- Extracellular signal-regulated kinase 1
- protein-tyrosine-phosphatase
- Tyrosine protein phosphatase
- G protein subunit beta
Sequence:
MKKSTGPTQTRQVVFNISQNFKVLKILGEGAYGIVALAVHLPTETKVAIKKIEPFERPLFCLRTLREIKLLTKFKNHDNIVRLYDVQKPMNYDSFNEVYLIQEYMPSDLHNIIHTHLLSDQHVQYFIYQILKGLKMIHSARVIHRDLKPSNILVNEKCDLKICDFGLARLDTKHYNFDEAPRISMLTEYVATRWYRAPEIMLSASNYSTAIDLWSVGCILAELLTYRALFPGSDYINQLKLIFEVLGTPTDEDLQIIKSERAQKFIRSLPTKVKIDLSEFINNHPYRNIKHRGRDQVNPLAIDLLEKLLVFDPAKRITVQDALEHPYLNSYHEQLDEPVTSPIPIEEFDFDIDKKNLDTNDLKKQIFEIVMS
Protein: Metabotropic glutamate receptor 2 (mGluR2) (Q14BI2)
Organism: Mus musculus (Mouse)
Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Subcellular location: Cell membrane; Multi-pass membrane protein. Synapse. Cell projection, dendrite.
Interaction partners:
- Guanine nucleotide-binding protein G
- 5-hydroxytryptamine receptor 2A
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Metabotropic glutamate receptor 3
- Metabotropic glutamate receptor 7
- Guanine nucleotide-binding protein G
- Glutamate receptor 1
- Metabotropic glutamate receptor 4
- Metabotropic glutamate receptor 8
Sequence:
MESLLRFLALLLLRGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATLSDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSERAAEGAITIELASYPISDFASYFQNLDPWNNSRNPWFREFWEERFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTDDEVRFDRFGDGIGRYNIFTYLRAGNGRYRYQKVGYWAEGLTLDTSIIPWASPSAGTLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGIGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAPRASANLGQGSGSQLVPTVCNGREVVDSTTSSL
Protein: Pyrophosphate-energized vacuolar membrane proton pump 1 (EC 7.1.3.1) (Pyrophosphate-energized inorganic pyrophosphatase 1) (H(+)-PPase 1) (Vacuolar proton pyrophosphatase 1) (Vacuolar proton pyrophosphatase 3) (P31414)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Contributes to the transtonoplast (from cytosol to vacuole lumen) H(+)-electrochemical potential difference. It establishes a proton gradient of similar and often greater magnitude than the H(+)-ATPase on the same membrane. In addition, facilitates auxin transport by modulating apoplastic pH and regulates auxin-mediated developmental processes. Confers tolerance to NaCl and to drought by increasing ion retention.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:17151019}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:21600394}; Multi-pass membrane protein {ECO:0000255}. Note=Mostly vacuolar, tonoplast (PubMed:17151019). Also present in endosomes and plasma membrane (PubMed:21600394). Localizes in sieve element-companion cell complexes (PubMed:21600394). {ECO:0000269|PubMed:17151019, ECO:0000269|PubMed:21600394}.
Interaction partners:
- Sodium/hydrogen exchanger 1
- V-type proton ATPase subunit a3
- Soluble inorganic pyrophosphatase 5
- Soluble inorganic pyrophosphatase 4
- Soluble inorganic pyrophosphatase 1
- Soluble inorganic pyrophosphatase 2
- Soluble inorganic pyrophosphatase 3
- Sodium/hydrogen exchanger 2
- Sodium/hydrogen exchanger 7
- V-type proton ATPase subunit c4
Sequence:
MVAPALLPELWTEILVPICAVIGIAFSLFQWYVVSRVKLTSDLGASSSGGANNGKNGYGDYLIEEEEGVNDQSVVAKCAEIQTAISEGATSFLFTEYKYVGVFMIFFAAVIFVFLGSVEGFSTDNKPCTYDTTRTCKPALATAAFSTIAFVLGAVTSVLSGFLGMKIATYANARTTLEARKGVGKAFIVAFRSGAVMGFLLAASGLLVLYITINVFKIYYGDDWEGLFEAITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGKIERNIPEDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYAEASCAALVVASISSFGINHDFTAMCYPLLISSMGILVCLITTLFATDFFEIKLVKEIEPALKNQLIISTVIMTVGIAIVSWVGLPTSFTIFNFGTQKVVKNWQLFLCVCVGLWAGLIIGFVTEYYTSNAYSPVQDVADSCRTGAATNVIFGLALGYKSVIIPIFAIAISIFVSFSFAAMYGVAVAALGMLSTIATGLAIDAYGPISDNAGGIAEMAGMSHRIRERTDALDAAGNTTAAIGKGFAIGSAALVSLALFGAFVSRAGIHTVDVLTPKVIIGLLVGAMLPYWFSAMTMKSVGSAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGCLVMLTPLIVGFFFGVETLSGVLAGSLVSGVQIAISASNTGGAWDNAKKYIEAGVSEHAKSLGPKGSEPHKAAVIGDTIGDPLKDTSGPSLNILIKLMAVESLVFAPFFATHGGILFKYF
Protein: SRY-box transcription factor 18 (Transcription factor Sox-18) (E7F9I2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- COUP transcription factor 2
- Vascular endothelial growth factor C
- Lymphatic vessel endothelial hyaluronic receptor 1b
- Vascular endothelial growth factor receptor 3
- Collagen and calcium-binding EGF domain-containing protein 1
- Prospero homeobox 1a
Sequence:
MNISESSCCQEASSQPSQVAERGTWGASSSTPGPERGHGFDRSRTTELAPVPGSGTRTVSRTAAEARTGSPDSTRPGALTLGSSEGKSGGESRIRRPMNAFMVWAKDERKRLAIQNPDLHNAVLSKMLGQSWKALSTLDKRPFVEEAERLRLQHLQDHPNYKYRPRRKKQPKKMKRVEPGLLLQGLAHGGPGDAYSPHRHAHHLLPPLGHFRDLHPSGAPELESFGLPTPEMSPLDVLEEGGGDSVFFPPHMQEDVGLSSWINYHQHPNHQPGHHPHHNSHNLQHSHPHLNQKSPLACLPLQEKCLVVESPNPGGLYPNMTLPESSKAGYYGQIYGSSQPQPAFTSHLGQLSPPPETSAVAQVAPPSLDAVDQLGPSAEFWGEVDRIEFDQYLSASRTRVSRSAPCEESSALISALSDASSAVYYSACITG
Protein: Suppressor of tumorigenicity 20 protein (Human cervical cancer suppressor gene 1 protein) (HCCS-1) (Q9HBF5)
Organism: Homo sapiens (Human)
Function: May act as a tumor suppressor. Promotes apoptosis of cancer cells.
Interaction partners:
- Cyclin-dependent kinase 2-associated protein 1
Sequence:
MARSRLTATSVSQVQENGFVKKLEPKSGWMTFLEVTGKICEMLFCPEAILLTRKDTPYCETGLIFLTLTKTIANTYFYF
Protein: Segmentation protein even-skipped (P06602)
Organism: Drosophila melanogaster (Fruit fly)
Function: May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair-rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes.
Subcellular location: Nucleus.
Interaction partners:
- Protein hunchback
- Protein sister of odd and bowel
- Protein odd-skipped
- Protein bowel
- Zygotic gap protein knirps
- Protein twist
- Huckebein
- Transcription factor Zelda
- Protein tailless
- Fork head domain transcription factor slp1
Sequence:
MHGYRTYNMESHHAHHDASPVDQKPLVVDLLATQYGKPQTPPPSPNECLSSPDNSLNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHPHMMGSSATGSSYSAGAAGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSAPSVPAPAPLTTTSPLPAPGLLMPSAKRPASDMSPPPTTTVIAEPKPKLFKPYKTEA
Protein: Transaldolase (EC 2.2.1.2) (Q6FXG5)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Transketolase
- Glucose-6-phosphate isomerase
- Triosephosphate isomerase
- Fructose-bisphosphate aldolase
- ATP-dependent 6-phosphofructokinase
- Fructose-1,6-bisphosphatase
- Fructose-1,6-bisphosphatase
- ATP-dependent 6-phosphofructokinase
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Glyceraldehyde-3-phosphate dehydrogenase 1
Sequence:
MSEPVQKKQKTNSSLDQLKASGTVVVADTGDFESIAKFQPQDSTTNPSLILAAAKQPAYAKLIDVAVEYGKKHGKTVEEQTEAAVDRLLVEFGKEILKIVPGRVSTEVDARLSFDKEATIAKALQIIKLYEEQGISKSRVLIKIASTWEGIQAARELESKHGIHCNLTLLFNFAQAVACAEANITLISPFVGRIMDYYKAKTGETYTGETDPGVKSVRAIYNYYKKYGYKTIVMGASFRNIDEIKALAGVDYLTISPNLLDQLLNSNDPVPKILDPATAKDEAGEKVTFVDNESAFRFALNDDAMATDKLSDGIRKFSADIITLFDMIEKKVKA
Protein: Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1) (Q9BXT4)
Organism: Homo sapiens (Human)
Function: Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Also present in chromatoid body (By similarity). {ECO:0000250}.
Interaction partners:
- Piwi-like protein 2
- Piwi-like protein 1
- Piwi-like protein 4
- RNA helicase Mov10l1
- Putative ATP-dependent RNA helicase TDRD12
- Probable ATP-dependent RNA helicase DDX4
- Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
- Transcription factor E2F1
- ATP-dependent RNA helicase TDRD9
- Protein maelstrom homolog
Sequence:
MSVKSPFNVMSRNNLEAPPCKMTEPFNFEKNENKLPPHESLRSPGTLPNHPNFRLKSSENGNKKNNFLLCEQTKQYLASQEDNSVSSNPNGINGEVVGSKGDRKKLPAGNSVSPPSAESNSPPKEVNIKPGNNVRPAKSKKLNKLVENSLSISNPGLFTSLGPPLRSTTCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSAHSIVCRPVQPNFHKLENKSSIETKDVEVNNKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIELPVDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDACCAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVHTVSVEKCSENGTVDVADKLVTFGLAKNITPQRQSALNTEKMYRMNCCCTELQKQVEKHEHILLFLLNNSTNQNKFIEMKKLLKS
Protein: Dorsal interacting protein 2 (SD09045p) (Q9NHV6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MATRSCAYKDCEYYYVGHENALTKGRTLFAFPKQPQRARIWHENGQVHPKIPHSQLFMCSLHFDRKFISSSKNRTLLVGEAVPFPYEESSSKPEEEPQQVASTSHESYYINLSDDELSINNVDTTSITTIDAVHDSPPQKRPKESSIVIALKEAVKMEPNPNAGRVRAEPDNIDTTEVSVFNFKGQEYVQMSMEYYLQEKRKMAKLLQDYKNALRSIKKHISHLDL
Protein: Probable activator protein in leuABCD operon (Q8Z9H8)
Organism: Salmonella typhi
Interaction partners:
- Conserved hypothetical regulatory protein
- Conserved hypothetical regulatory protein
Sequence:
MPEVKTEKPHLLDMGKPQLRMVDLNLLTVFDAVMQEQNITRAAHTLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPGSGFEPTSSERVFNLCVCSPLDNILTSQIYNRVEKIAPNIHVVFKASLNQNTEHQLRYQETEFVISYEEFRRPEFTSVPLFKDEMVLVASRKHPRISGPLLEGDVYNEQHAVVSLDRYASFSRPWYDTPDKQSSVAYQGMALISVLNVVSQTHLVAIAPCWLAEEFAESLELQILPLPLKLNSRTCYLSWHEAAGRDKGHQWMEDLLVSVCKR
Protein: Serine/threonine-protein kinase PBL36 (EC 2.7.11.1) (PBS1-like protein 36) (Receptor-like cytoplasmic kinase PBL36) (F4J0D2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in chitin-triggered immune signaling and is required for reactive oxygen species (ROS) production. Acts downstream of SD129 in defense signaling triggered by the pathogen-associated molecular pattern (PAMP) 3-OH-C10:0, a medium-chain 3-hydroxy fatty acid.
Subcellular location: Cell membrane {ECO:0000269|PubMed:31922267}; Lipid-anchor {ECO:0000250|UniProtKB:O48814}.
Interaction partners:
- Transcription factor MYB104
- Senescence associated gene 20
- Scarecrow-like protein 27
Sequence:
MATKLESFKVVEKLGVEKGEKGKMMSKKKNVKKDGDESESGFWFRFKFIFSCISSRSKVDSSMNATAVIAEPKKVIEKLEGHPAPTKDTGCAESGSSTPLMSGELKYSSKLRIFMFNDLKLATRNFRPESLLGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPDGLQGHKEWLAEINFLGNLVHPSLVKLVGYCMEEDQRLLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLHEEAEKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEKKSHVSTRVMGTYGYAAPEYVMTGHLTTKSDVYSFGVVLLEILTGRRSVDKSRPNGEQNLVEWVRPHLLDKKRFYRLLDPRLEGHYSIKGAQKATQVAAQCLNRDSKARPKMSEVVEALKPLPNLKDFASSSSSFQTMQPVAKNGVRTQGGGFVSRNGPPMRSLSSLNLPQASPYRYARQSPKPKGKEP
Protein: Reticulon-2 (xRTN2) (Q4FZ76)
Organism: Xenopus laevis (African clawed frog)
Function: Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (By similarity). Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity). Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15765506}; Multi-pass membrane protein {ECO:0000255}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:O70622}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q6WN19}; Multi-pass membrane protein {ECO:0000255}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:O70622}; Multi-pass membrane protein {ECO:0000255}. Cell membrane, sarcolemma, T-tubule {ECO:0000250|UniProtKB:O70622}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:O70622}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O70622}.
Interaction partners:
Sequence:
MGHVLSFTHCKDAPSTASSTPDSCPLEGEDDDTPVTEVDFWPLPSPHEPTFSYITIGSSAPLSRPPVRARRGLGQGRVHEAPREETEEKEVKDVVNYVLLENTCELKQISPLQVQEEVVFVAKPQPQVEVFRAVKDLLYWRDTLLSTGCLTGVTLSLLCLSQFSVISVFAYGCLIILSVTLTLRLYTKLLHALKRGNGANPFQYYLDTDLKLTTKQAEEIVARAFSLASTTLCTLRSLFLVEELKDSLKFLVIVYLLTYVGAVFNGITVLLLCVIGAFTFPILYKQHQTQVDHYVSLVSKKVNAFRSKFQGAAKKPPAKQK
Protein: Sperm-tail PG-rich repeat (Q57XU0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDTYSKLSLVKENDVDVNDVQAQVDVMYASILASVDMIMEKEAAAARKGAPTRGAAHHFKQRGTQAASSCASAAPPKPETRCALPATETKEPDEAAETCASQCGCSCAHECTSMGPKASSGCQHVRRHNSQLAATKCRRPHEASAEKVKIPYSTPTGRVVNAATVTRSSQHRFPPSTFGSGRKGMSEPIRKDTSPGPGSYFIADDSNNDSGDCYRGRGAEAGHSKKSHTSGPHHTGVEVVEQKAEKNELLKRQMEILCQCYWKQMPDIDAPKNPAAHASDCPCQSLRTVCTEGDNDDHTSSRSNSGSEAAQPCGSSTKKNSNKKSGATKAHDSFQKSPSVVSPRLVGRLSNRGAVFGISPRCTIFAVDTSDTNTHPKHRSSQRRRGRSEEEVRSGQRAVGDSDVHGSVPSYLKPTKRVDGASAGVSPGPGAYDVSGELGMSALSPGKTATGGVLIGRAERKLHAVNNFPGPGAYDVKEKSMTETSSKKSARTLSSSRRQLSILPTKEAVLIPGPGEYHPEAATLSDARRRSPPAFSFGRAKLLRYGRVPLTSSPPSEPANVPGPGTYDTASVPSDRCTAVSGRSAVITNVRRGGSPWSKERTSPHEVPGPGAYEPVRRESGPAYLMGRRPAERVDTTPGPGHYELPQMSTGPRWLVSESPSAPLEPHPTPGPGEYSVSTYELKHSHSSAPLFPTAPRVLHEGTKVAETLPGPGTYETERQTSPVRSAIMGTAQRVSTLGFDCCADVPGPGTYTALTTVQEPRVVSPLLNAAAPRFAESSEPGAEGAAGVVATPGPGHYDADCGDVGTRGRAAVFGSAPRELPFNEDEAAKKPGPGAYEIAMPKNSPSFSIGQKLDGPEPSVSVPGPGEYDPQDPMPNTRAVVIGEAARFQTSGGEKDRQDVPGPGAYTIERPPEYRGAAVFGTEPRLLTIDHSVGNHDGNDGIGPGSYDPQVPKGPASGAVWSAGPRFAADTLNEVPGPGAYDTRQSPTPTNVVNFGISCGKPSQRADPAEAVPGPGAYAPKDPHGRTIPGVVFGSSPQHPTSPEEREALMRPGVGPGSYEVILPVPHTFHTTFGSAADGRIQEERHGELAVGPGHYNPHDSKASCARSAIIGMAPRLQSHEDSWSIPGPGAYSLDPTTGGASPVGPVSFTTAPRFDNVAGAAAGGDNDVTPGPGYYSIEDRGTLTAAAGVPVFSRGPRVLDLKEREHALLPGPGQYHPEDLSTKVGGAAYSFGVEPRMPQDATENDGTTPGPGAYDVTIPTLTATGTRFGVEPRALGSLNHEEGPGPGTYNVGASRTTSPTAPVYRFPTATREAPSLEGSDVPGPGQYDYTGEDLSHRRAVVSAFPISPRFATERGEDEAPGPGQYMPHHPQWDSSQAYSFPMGGRNASLTLGTDGPGPGTYSPQEPSLTATAALFGIGPRQTSGGLNNLSGQNHPGPGHYNPALPTDTPSVIFGTAQRDVANTGGIEDAPGPGSYDLRVENREGIAYSIGRAAAQDRMAVDMQKAELPGPGTYSVQPAFPAVDGGSGATSFVKAARFPDGQAAQTEGPGPGAYSIQSAQRTSGPFIGRAPRVATGVGANNNDLREQPGPGHYEVSSGGLGSIVDGGVAMRFTSERFPGLSGGAVGESPGPASYSPAEARGTKDGVSFPQAPRHSPAELNDASSRPGPGDYDIPSTWNTTAGNTYSFGAEERMKAPTVDADVPGPGSYDTNRYLNAYQAGPAFTLKSKPGQNENGGDLPGPGSYDASRYIDESRAGRAFTLRGKSTFNGSSGNGDVPGPGSYDPNRYLEQCQAGPSVSLRGKAAPVGGHDADVPGPGSYDASSYLERCQMGPAFSLKGKPTCVDENSAGIPGPGSYDANRYLEQFQSGPAFTLRGKGACNGNDSEADVPGPGSYDPNRYLEQHHAGPSFTLKGKATYNGENGIDAPGPGSYDINRCMEQSQAGPSFTLRGKPSDTGQKGPDIPGPGSYDASQYLERCQAGPAFTLRGRDAFNSNSADGDVPGPGSYDVNRYLKQCQSGVSFTLKGKSAQNDNEADAPGPGSYDPNRYLEQHHAGPSFTLKGKATYNGENGIDAPGPGSYDINRYMELCQAGPAFTLKGKASQVEGSADVPGPGSYDVSRYTEQFQSGPAFTLKGKQVTSDGVDADVPGPGSYNVSSYAEQFKPGPAFTVKGKPSGAAENSDGLPGPGSYDTDRYMQQCHSGPAFTLKGKPTYGDGRQTEDVPGPGAYCPRPTETTRAVSFGPLPTVDSTAVFEVRVNATPGPAAYVIPSTLNQKAVPFGAAEREVQCRAEDVPGPGAYLTGGPVVLKPGPAFTFGRGPRSMTLESAQEDAPGPGEYHHPVDARPTVLAFTFASADRFAEFEAGNGVGPGEYYHPYPTETHGGPAFRFPKSMRAA
Protein: Tumor necrosis factor alpha-induced protein 8-like protein 3 (TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3) (Q3TBL6)
Organism: Mus musculus (Mouse)
Function: Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25479791}. Cell membrane {ECO:0000269|PubMed:25242044}. Note=On PDGF activation, translocates from cytoplasm to plasma membrane. {ECO:0000269|PubMed:25242044}.
Interaction partners:
Sequence:
MDSDSGEQSEGEPGTAAGPHVFSSKNLALQAQKKILSKIASKTVANMLIDDTSSEIFDELYKVTEIHTHNKKEAHKIMKDAIKVAIKIGILYRNKQFSQEEVIIVEKLRKKLNQTAMTMVSFYEVEYTFDTNVLSKLLHECKDLVHELVQRHLTPRTHGRINHVFNHFADVEFLSTLYGPHGNCRPNLKRICEGINKLLDDKIL
Protein: Protein CHLORORESPIRATORY REDUCTION 7, chloroplastic (Q9FL87)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for both formation and activity of the chloroplast NAD(P)H dehydrogenase (NDH) complex of the photosynthetic electron transport chain. May function in assembly or stabilization of the NDH complex. Required for the accumulation of NDH subcomplex A, which is a core part of NDH. May be involved in post-translational steps during the biogenesis of subcomplex A.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:20444231}. Note=Previously localized in chloroplast thylakoid membrane fraction. {ECO:0000269|PubMed:16359395}.
Interaction partners:
- NAD
- Protein CHLORORESPIRATORY REDUCTION 6
- Protein CHLORORESPIRATORY REDUCTION 42
- Dihydrodipicolinate reductase-like protein CRR1, chloroplastic
- NAD
- NAD
- NAD
- At1g78995
- Photosynthetic NDH subunit of subcomplex B 5, chloroplastic
- Photosynthetic NDH subunit of subcomplex B 4, chloroplastic
Sequence:
MECSLQKQLFNNGDKLFSSRHNRRVSIEQVHVTDSLSVNSINLFHKPICYPISSIITSRKSKSHFSVCATRRRRVHSNSDTYVLLEAGQDEQFVTEDELKAKLRGWLENWPVNSLPPDLARFDDLDEAVDFLVKAVCELEIDGEVGSVQWYQVRLE
Protein: RE12039p (Q8IGW6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKRAYYAATVIRQMQRMALNSNSNANFDSSNSSNQDSTTPTAATGAWTSNVLSSQQSVQSHAQEMNKSGGSTNAASQ
Protein: Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP) (P50238)
Organism: Homo sapiens (Human)
Function: Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein.
Interaction partners:
- Rhombotin-1
Sequence:
MPKCPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCNHPCYAAMFGPKGFGRGGAESHTFK