wanglab/gogpt-training-data huggingface dataset:
Protein: Beta-conglycinin alpha' subunit (CG-alpha'-1) (Beta-conglycinin alpha prime subunit) (allergen Gly m 5) (P11827)
Organism: Glycine max (Soybean) (Glycine hispida)
Function: Seed storage protein. Accumulates during seed development and is hydrolyzed after germination to provide a carbon and nitrogen source for the developing seedling.
Subcellular location: Vacuole, aleurone grain {ECO:0000305}. Endoplasmic reticulum {ECO:0000269|PubMed:15447650}. Protein storage vacuole {ECO:0000269|PubMed:12787246, ECO:0000269|PubMed:15447650, ECO:0000269|PubMed:16900322, ECO:0000269|PubMed:17181539}. Note=Localizes in protein storage vacuoles in cotyledons of developing and mature beans (PubMed:12787246, PubMed:15447650, PubMed:16900322, PubMed:17181539). Synthesized and assembled into trimers in the endoplasmic reticulum, and transported to the protein storage vacuoles by the dense vesicles (PubMed:15447650). {ECO:0000269|PubMed:12787246, ECO:0000269|PubMed:15447650, ECO:0000269|PubMed:16900322, ECO:0000269|PubMed:17181539}.
Interaction partners:
- Glycinin G1
- Glycinin G2
- Uncharacterized protein
- Glycinin G4
- Cupin type-1 domain-containing protein
- Flavonol-3-O-glucoside/galactoside
Sequence:
MMRARFPLLLLGVVFLASVSVSFGIAYWEKQNPSHNKCLRSCNSEKDSYRNQACHARCNLLKVEEEEECEEGQIPRPRPQHPERERQQHGEKEEDEGEQPRPFPFPRPRQPHQEEEHEQKEEHEWHRKEEKHGGKGSEEEQDEREHPRPHQPHQKEEEKHEWQHKQEKHQGKESEEEEEDQDEDEEQDKESQESEGSESQREPRRHKNKNPFHFNSKRFQTLFKNQYGHVRVLQRFNKRSQQLQNLRDYRILEFNSKPNTLLLPHHADADYLIVILNGTAILTLVNNDDRDSYNLQSGDALRVPAGTTYYVVNPDNDENLRMITLAIPVNKPGRFESFFLSSTQAQQSYLQGFSKNILEASYDTKFEEINKVLFGREEGQQQGEERLQESVIVEISKKQIRELSKHAKSSSRKTISSEDKPFNLRSRDPIYSNKLGKLFEITPEKNPQLRDLDVFLSVVDMNEGALFLPHFNSKAIVVLVINEGEANIELVGIKEQQQRQQQEEQPLEVRKYRAELSEQDIFVIPAGYPVVVNATSDLNFFAFGINAENNQRNFLAGSKDNVISQIPSQVQELAFPGSAKDIENLIKSQSESYFVDAQPQQKEEGNKGRKGPLSSILRAFY
Protein: At2g42750/F7D19.25 (DNAJ heat shock N-terminal domain-containing protein) (Expressed protein) (Q9SJI1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cell division cycle 5-like protein
- Protein CONSERVED IN THE GREEN LINEAGE AND DIATOMS 27
- Pre-mRNA-processing factor 19 homolog 2
- Transcriptional regulator ATRX
- AT4g21110/F7J7_50
- Protein pleiotropic regulatory locus 1
- Protein pleiotropic regulator PRL2
- Pre-mRNA-processing factor 19 homolog 1
- U2 small nuclear ribonucleoprotein A'
- rhamnogalacturonan endolyase
Sequence:
MAQILSPVCTDLLKFQNSALSSRSGASPRFSAKTTGASSSWYLPRYAGKRRTDSIGRLRVATEDASSLSTGDVADDYYAVLGLLPDATQEEIKKAYYNCMKSCHPDLSGNDPETTNFCMFINDIYEILSDPVQRMVYDEIHGYTVTAINPFLDDSTPRDHVFVDEFACIGCKNCANVAPDIFQIEEDFGRARACNQRGNPDLVQQAVETCPVDCIHQTSAAQLSLLEDEMRRVERVNVALMLSGMGSGAVDVFRMARSRWEKRQAKVLNQARSRMMKRKNTDETPSYWDNLWGKQNEYQKSEEEVQERAQRAAAAARRWREYSRRGVDKRPTFKLPDSASRGDN
Protein: Serine/threonine-protein kinase ppk35 (EC 2.7.11.1) (Meiotically up-regulated gene 27 protein) (O94487)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Maintenance of ploidy protein mob1
- Tyrosine-protein phosphatase CDC14 homolog
- Cell division control protein 7
- Septum-promoting GTP-binding protein 1
- Rab guanine nucleotide exchange factor sec2
- Serine/threonine-protein kinase plo1
- Sporulation-specific protein 13
- GTP-binding protein ypt2
- Sporulation-specific protein 2
- Protein phosphatase PP2A regulatory subunit B
Sequence:
MDLLGLKELDNNKLVSKAKENGVEFSDLFLLSSGYLRDRENASASVSSKNERMVLNEERQNCWTKRNDPKGLTYYQLLKPSEVEILSRPETRRKRMACQVFFLNYYISTIEYHKLRKERLEEFTACTSSLKQSKQKRLWKEHCGRERAFLRKKRTKIQCSHFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSAVNPQRPYLTQKQRRNIYKALLEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGSTLQETWTNLYYWREMLQRPSKNENGIYDKKARSVSDEAWSFITKCLTEPTSRFQSTIEIQKHPFFKRLHWNGLRKRAVPPFVPRLENQLDTSYFDDFNDEQVLDAYKDVYEKQRKAEQKAKSNGVMNGNQRQFLGFTFKYRPNARKPLVGRHREKRQLRKEKPEKKNNSTKQKDLITVSHNKGTTAIEDLDEDKRSKTKGHKTKSSRVHRLLERKGKDLYEFLL
Protein: Activator of basal transcription 1 (Q8IRM9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- rRNA biogenesis protein RRP36
- KRR1 small subunit processome component homolog
- ATP-dependent RNA helicase
- Probable ATP-dependent RNA helicase Dbp45A
- Bystin
- Uncharacterized protein, isoform A
- Nucleolar protein 14 homolog
- EG:8D8.4 protein
- U3 small nucleolar RNA-associated protein 18 homolog
- RE67794p
Sequence:
MKVEETKLGEVRSGKPQTKEGESANGVANPSNDDKKELANFKATFNSWAPEKKREKMHKVGVILISNIPKDMDGDCLKEIMNLHSVVGRVYVQPETLSSFKTKKNMRKGWVEFISKSGAKKIALELNNKPITDGKSSRFRGLLWKMKFLPRFKWYYLTDRMDYELAVCKVRVWSQARKRATFLYDPDQMEYFKKQVKKMKKVKKAEMATRNAEMAAKKAEMAAKKLKKSA
Protein: C-C motif chemokine 21a (6Ckine) (Beta-chemokine exodus-2) (Small-inducible cytokine A21a) (Thymus-derived chemotactic agent 4) (TCA4) (P84444)
Organism: Mus musculus (Mouse)
Function: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.
Subcellular location: Secreted.
Interaction partners:
- C-C chemokine receptor type 7
- Atypical chemokine receptor 4
- C-C motif chemokine 19
- C-C motif chemokine 21b
- C-X-C chemokine receptor type 4
- C-X-C chemokine receptor type 5
- Stromal cell-derived factor 1
- Fractalkine
- C-X-C chemokine receptor type 3
- C-C chemokine receptor type 5
Sequence:
MAQMMTLSLLSLVLALCIPWTQGSDGGGQDCCLKYSQKKIPYSIVRGYRKQEPSLGCPIPAILFSPRKHSKPELCANPEEGWVQNLMRRLDQPPAPGKQSPGCRKNRGTSKSGKKGKGSKGCKRTEQTQPSRG
Protein: Lysine-specific demethylase JMJ705 (EC 1.14.11.68) (Jumonji domain-containing protein 705) (Lysine-specific histone demethylase JMJ705) (Protein JUMONJI 705) ([histone H3]-trimethyl-L-lysine(27) demethylase JMJ705) (Q5N712)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3 with a specific activity for H3K27me3 and H3K27me2. No activity on H3K4me3, H3K9me3, H3K27me1 and H3K36me3. Involved in biotic stress response. May demethylate H3K27me3-marked defense-related genes and increase their basal and induced expression levels during pathogen infection.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000269|PubMed:24280387}.
Interaction partners:
- Nitrate reductase
- Nitrate reductase
- Nitrate reductase 1
- protein-serine/threonine phosphatase
- WUSCHEL-related homeobox 11
- Os04g0589400 protein
- Small ribosomal subunit protein uS2c
- Os01g0220300 protein
- Os06g0255200 protein
- Os02g0102400 protein
Sequence:
MRPSPPPAAPAAEPVPPWLRSLPVAPEFRPTAAEFADPVSYILKIEPAAAPYGICKVVPPLPPPPKKATFSNLSRSFAALHPDDRSPSFPTRHQQVGLCPRRTRPGLKPVWRSSHRYTLPQFESKAGATRKSLLAGLNFPASRQLTPLDHEVLFWRASADRPIVVEYGSDMSGSGFSPCAAQPQPPPQQQPTARAAAHLGETAWNMRGVARSPGSLLRFMPEDVPGVTTPMLYVGMMFSWFAWHVEDHDLHSLNYMHLGAAKTWYGVPRDAALAFEDVVREHGYGGEVNPLETFATLGQKTTVMSPEVLVESGIPCCRLVQNAGEFVVTFPGSYHCGFSHGFNCGEASNIATPEWLRIAKEAAIRRASINRPPMVSHYQLLYDLALSMRFREPSNGEMETRSSRIKEKKKCEGEQLVKKMFIQNVIEDNELLSHLLNDGSSCIILPANAHDGPGLSTLRSTDQSNMNSRISHNLCSREEAPEASGCLSPNRNGDTRNCISSDTHNMEGDKGDIMSATGLLDQGLLSCVTCGILSFSCVAVLKPRDSTARYLMSADSNSINNQLSISGGSILADAPTNERNGVISRPYSEHCCNEIMADDAEIDKNSALDLLAFAHGGQPDPEEDPLEKILKIAHGINKSQPNSSNNVGCVGTKLSSSSTERQERPSSQNAHCNGSSVISNGPKGVRTRNKYQLKMVLSEGFQAKDIYSAKEKKVQSEPSSSKGDVKETIDVSGTENDVGCKSTTISVSEHRGSTKNMYSVKEKKVQSKPSSLKGTVKETVDVSGTENDARCKSITISVSEHRGSTPMTNSLAASIVKPDKDSSRMHVFCLEHAIEVEKQLHAIGGSNIMLICRPEYPKIEAEARLLGEEMGLVYDWKGIHFKEANMEDRQKIQEVLRDEEAIPTSSDWAVKLGINLYYSANLAKSPLYNKQMPYNRVIYRAFGCDSPNDSPVMFNTCERKQSHQKKIVVAGRWCGKVWMSKQVHPYLAHRVESQEAEEADRICSYHFDEKHKAEPVGNSSRVEASKRKSSSLTDVTESSNRRGEIPGEETNTKRPKHSQENNLRALETAAEVVVPSPAGTGLRVSSRIANRANKLKSKMEKEDVPSSRPKSNIKEKSSHASGQKSNVQEANANSASHLRAMPPKQKAEAEAKKQIRTPKPPKQAVEYSCDIEGCSMSFRTKRDLSLHKSDICPVKGCGKKFFSHKYLLQHRKVHTDDRPLTCPWKGCNMAFKWPWARTEHLRVHTGDRPYVCHEPGCAQTFRFVSDFSRHKRKTGHSVKKKKKAKS
Protein: DNA replication ATP-dependent helicase/nuclease JHS1 (Protein EMBRYO DEFECTIVE 2411) (Protein JING HE SHENG 1) [Includes: DNA replication nuclease JHS1 (EC 3.1.-.-); DNA replication ATP-dependent helicase JHS1 (EC 3.6.4.12)] (A0A1P8ASY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protein required during embryogenesis. Key enzyme involved in DNA replication and damage repair, shoot apical meristem (SAM) maintenance, and development. Involved in Okazaki fragments processing. Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5'-3' helicase and endonuclease activities. While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is atypical: it cannot load onto its tracking strand internally and has an absolute free 5'-end requirement (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:26951435}. Chromosome {ECO:0000250|UniProtKB:P51530}. Note=Localized to nuclear foci in response to DNA damage. {ECO:0000269|PubMed:26951435}.
Interaction partners:
- Protein ENHANCER OF LHP1 1
- Probable DNA primase large subunit
- DNA polymerase alpha catalytic subunit
- Flap endonuclease GEN-like 1
- Single-strand DNA endonuclease 1
- Flap endonuclease 1
- DNA polymerase epsilon subunit B
- DNA primase
- Replication protein A 32 kDa subunit B
- Exonuclease 1
Sequence:
MPPRKKPKSSALKSNKQSSANHSSQPSTFGIQQLFLRHIQNSQSTSNSHTSTADPVDQQNVNGLASDTAVLTPQNPLGTSNEKPDESKDMDQQLTEASPKISKNLKRFSPGMLIKQSQDDCGGEITWKISPVNERLRAAAKNIPKMMDLTENSLGVKSSTIRPCSLNKLVQKQCPTSGITSKVEQWLSSPSKKASKRPAFATNRVMERVNPSPDAEFEIVNTSSSGNSPFQTPPSLSCPHNKLPCTVTCSGACGSMGAGQHKKALLELLDQVEDVIAVDDKTTDDVGIVMPQARVKDDIISSVVDCAVDEGPVSLPKMQNSINPDSYFLVLEVSEKRGSGSSSKGQCPYKVLRLLDEHTGVECALYLWDEWFYSTVSPGDSINVIGEFDGDGKCDVDRQNNFLIVHPDTLVAGTRVAASFGCPRRTVLDERLRSNEHATVALLGTLQHQVFQAGLSQESPSVDGLQEYASTVIEKSIESLYACGVHEGDVRSTLFKAIPKMLNWIEHFRYSKDSEVSKVDFGSTIGKKAVKVSEVIDIEEMSWAPKYGLKGMIDASVRVIVESDMNTVNEKIMPLEFKSGKAPSGQSSIEHSAQVILYTLLMSERYLKHIDNGLLYYLQSDQTQGISVQRSDLVGLIIRRNELANDILVASTTQQLPPMLRNPNICRNCRHLDVCTIYHKADGGNTESSGLGDVFDTHVSHLSTLHFNFLRHWDRLIDLEGREMQLLRKDIAHPHGSKGSHSASYLSSMVLDVTNGFQHHNSHKETRFIYRFVRQKSSESRERVTSEDMIRTGNLATDDLDCKLRTGDRVILRTEVSHLTVANGIIADISRTHISVSLSKRLRLPWSEPSSEVSNLSHELWRIYKDEFMTSFSVMRFNLMQLFVQNGHNIRKMIVDLEPPRFDNGSILSQDPAISYIWSEKSLNNDQRQAILKILTAKDYALILGMPGTGKTSTMVHAVKALLIRGSSILLASYTNSAVDNLLIKLKAQGIEFLRIGRDEAVHEEVRESCFSAMNMCSVEDIKKKLDQVKVVASTCLGINSPLLVNRRFDVCIIDEAGQIALPVSIGPLLFASTFVLVGDHYQLPPLVQSTEARENGMGISLFRRLSEAHPQAISVLQNQYRMCRGIMELSNALIYGDRLCCGSAEVADATLVLSTSSSTSPWLKKVLEPTRTVVFVNTDMLRAFEARDQNAINNPVEASIIAEIVEELVNNGVDSKDIGIITPYNSQASLIQHAIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDWHRINVALTRAKKKLIMVGSQRTLSRVPLLMLLLNKVKEQSGILNLLPGDLKP
Protein: Serine/threonine-protein phosphatase PP1 isozyme 2 (EC 3.1.3.16) (Type one protein phosphatase 2) (P48482)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine/threonine-protein phosphatase that possesses phosphatase activity toward para-nitrophenyl phosphate (pNPP) in vitro.
Subcellular location: Nucleus {ECO:0000269|PubMed:19329567, ECO:0000269|PubMed:21222654}. Cytoplasm {ECO:0000269|PubMed:19329567, ECO:0000269|PubMed:21222654}. Note=Predominantly localizes in the nucleus. {ECO:0000269|PubMed:21222654}.
Interaction partners:
- Protein phosphatase 1 regulatory subunit INH3
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Flowering time control protein FY
- Transducin/WD40 repeat-like superfamily protein
- Protein ANTHESIS POMOTING FACTOR 1
- Cleavage and polyadenylation specificity factor subunit 2
- Cleavage and polyadenylation specificity factor subunit 3-I
- Putative 26S proteasome non-ATPase regulatory subunit 8 homolog B
- 30-kDa cleavage and polyadenylation specificity factor 30
- Serine/threonine-protein phosphatase PP1 isozyme 5
Sequence:
MAQQGQGSMDPAALDDIIRRLLDYRNPKPGTKQAMLNESEIRQLCIVSREIFLQQPNLLELEAPIKICGDIHGQYSDLLRLFEYGGFPPTANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFSVRLWKVFTDSFNCLPVAAVIDDKILCMHGGLSPDLTNVEQIKNIKRPTDVPDSGLLCDLLWSDPSKDVKGWGMNDRGVSYTFGPDKVAEFLIKNDMDLICRAHQVVEDGYEFFADRQLVTIFSAPNYCGEFDNAGAMMSVDESLMCSFQILKPADRKPRFL
Protein: Rano class II histocompatibility antigen, B-1 beta chain (RT1 class II histocompatibility antigen, B-1 beta chain) (RT1.B-beta(1)) (P29826)
Organism: Rattus norvegicus (Rat)
Function: Involved in the presentation of foreign antigens to the immune system.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Rano class II histocompatibility antigen, B alpha chain
- Rano class II histocompatibility antigen, D-1 beta chain
- H-2 class II histocompatibility antigen gamma chain
- Histocompatibility 2, class II antigen E alpha
- T-cell surface glycoprotein CD4
- Major histocompatibility complex, class II, DM alpha
- Hla-dmb protein
- T-cell receptor alpha chain V region PHDS58-like.
- RT1 class II, locus DOa
- RT1 class II, locus Ha
Sequence:
MALQTPSFLLPAAVVVLMVLSSPGTEGRDSPRDFVYQFKGLCYYTNGTQRIRDVIRYIYNQEEYLRYDSDVGEYRALTELGRPSAEYFNKQYLEQTRAELDTVCRHNYEGSEVRTSLRRLEQPNVAISLSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTQLIRNGDWTFQILVMLEMTPQRGEVYICHVDHPSLESPVTVEWRAQSESAQSKMLSGIGGFVLGVIFLGLGLFIRHKRQKGPRGPPPAGLLQ
Protein: Protein unc-87 (Uncoordinated protein 87) (P37806)
Organism: Caenorhabditis elegans
Function: Thin filament-associated protein that is implicated in actin bundling and actin filament dynamics. Exhibits F-actin cross-linking activity. Required for the maintenance of sarcomeric actin organization in striated muscles. Competes with unc-60 isoform b for actin binding and protects actin filaments from depolymerization by unc-60, thereby contributing to actin filament stability. Cooperates with myosin to form actomyosin bundles and inhibits actomyosin ATPase activity and actomyosin motility. Might protect the myofilaments from mechanical stress.
Subcellular location: Cytoplasm, myofibril, sarcomere, I band {ECO:0000269|PubMed:17684058, ECO:0000269|PubMed:25717181}. Note=Absent from the distal edges of the thin filament. Isoform b: Partially overlaps with the region where myo-3 is located. {ECO:0000269|PubMed:17684058, ECO:0000269|PubMed:25717181}.
Interaction partners:
- Calponin-homology
- Ig-like domain-containing protein
- Calponin-homology
- Troponin T
- Troponin I 2
- Paramyosin
- Troponin T
- Disorganized muscle protein 1
- Actin
- EF-hand domain-containing protein
Sequence:
MLSFNNTTSASSFQSASSRYLMSSSSSIGPPQQQSAKLFPEHFYPSGLSPRQSEALERLRPNTASRERNIPIQFTGKNPTTNSALEEYKPVPHVQVTSPKSSIVPNFVSEQRGLQPQPTSQAPTNYRQFVAAPRSPRGYGDYPEMTGKASAAGDSEPVQIPIKTQTPITQARAQETKIPTIVSPHPVYYYDNQEQPIQQIREEQPNATMETKVTGQGQPKRVGRWTLAQLRQTDGIIPSQAGWNKGDSQKLMTNFGTPRNTNTRVKSENLQEIPEDIANRTHGEVRLQSGTNKYCSQRGMTGFGSGRDVCREGVRVAQNPADLAELPEEKIRMSEGIVRLQAGTNKYDSQKGMTGFGTGRRETTKMVDSKHPEYDHEKPDQSEIPLQSGTNKFASQKGMTGFGTARRETTKMVDSNHPDYSHECSIDQTTIPSQMGSNQYASQKGMTGFGQPRWEVLDPSISWQNRKSQGMVRLQSGTNRFASQAGMIGFGTCRNTTFEAEGGELPYEAMKVSETIIPSQAGWNKGDSQKKMTSFGAPRDVKGKHLKRIWELEYPEEAEISLDRL
Protein: AT13539p (GEO08637p1) (Q9VPP7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GH19585p
- Proteasome assembly chaperone 2
- Proteasome assembly chaperone 1
- GEO05038p1
Sequence:
MNHTANKPRQIGFDRQFSADVNGVPTEIVFHCFAKKWFLVITQLGKIPGIYNVHFDVKKDERVVPYLHGPVDNPEFHVSVPITMNCCLGLDTDETRSAIQFLVNRTGLHKCPTEFVVGLGLKKIDGPNLRALAKVLEETLF
Protein: Ankyrin 2 (A0A5F9ZI08)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MTTMLQKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGRASPCLERDNSSFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIRRYVSSEGTEKEEIMVQGMPQEPVNIEEGDGYSKVIKRVVLKSDTEQSEDNNE
Protein: Cyclin-dependent kinase inhibitor 1A (A0A8I5ZZ18)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSDPGDVRPVPHRSKVCRRLFGPVDSEQLSRDCDALMASCLQEARERWNFDFATETPLEGNYVWERVRSPGLPKIYLSPGSRRRDDLGGDKRPSTSSALLQGPGPAPEDHVALSLSCTLVSHAPERPEDSPGGTGTSQGRKRRQTSLTGKDRRRGGKILREAWRGEAAC
Protein: Moesin/ezrin/radixin homolog 1 (B7Z0J2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell junction, adherens junction {ECO:0000256|ARBA:ARBA00004536}. Cell projection, rhabdomere {ECO:0000256|ARBA:ARBA00043944}.
Interaction partners:
Sequence:
MLRFLSRRKVRNNYVDNSREGGGATSSAVGVAGGGGAITSGGSSQIKPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSGRTEFQTTQQSRARRTVQFERRPSQRFASRQSHLLRERQKASQEAAVSAVASVNARAAAAAAAAAASQSPAPATPLVSSQVSTPTPNNDNNNDAFDSLISTDQFITVTPSPSVLTVIQNSAIIEPDAACSGSISSSSQAAANFASLGRNSLKSNFSNEDPAYSKIGSIGKASGLTVKLDPDYTPPYSPNATKNFDETNPFRNATSSHHGSFGKASISSGQLSVKSGLSDKDRELDSLLKSIVKDPSPSVLANEAINDANSIRVTINKTFDMDHNTETLKRLSNANEKPNNQVKLANVNTTALPPGNIKCNILKARVEEELGAGGNAKLTNQMFVPAAHSSNMHTSNTNSSNNHAHSDGPDSLNATYISVGGDKLTLSIPEQKPSTGSSSSSSTSSTATTTTNGNGPYSNATFVSGFSAPLTPPSSLPANLNNTGSGCNTTLTSVTTISTPSSPTATVSTTASESVAPALSNASAAEILINEIFINNIINNNASGSITAETAAKPAGSSTPSAGTLLFSTLSEQERLESQKTNQQMNQSLNLNQNHSEVDAPPSEKV
Protein: Ankyrin repeat and SOCS box protein 13 (ASB-13) (Q8WXK3)
Organism: Homo sapiens (Human)
Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Interaction partners:
- Cullin-5
Sequence:
MEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLTLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSYN
Protein: Transcription factor P14E8.02 (Q9P7G6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable transcriptional regulatory protein Required for G1/S progression.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Double-strand break repair protein rad32
Sequence:
MNISSQNVLLPSPIPSSSPMASHKKSWLSKHPNQSMTFEKPQLGQFVLTPEPSSNTFYAPSSPASAVRREPLSPMSFVRMRSHRVNKIGRSSQQCDHVLSTVDKAISRVHAIVTCTQDRMIIECVGWNGMIVSDKMRKSVFHMKKNDRIVLVRPNSDACPVLDVFGYRVLLGWPSDSEDEWEGNLNAKNYEENREPMSPSPQEALPLMPSSPPSQDYQNDQNHLILYTNSESIPKLNLRSNELVYPPPSKDLLQKLLALEKDGQVEKSDCSKNTQLKPSFLPKNTDDLLNGTDDNNIVLREVKVSFENEKIESDDLDKNEEISEGEEYTPIEESKEPITVRRDSVIQIDESSAGLTDVISELNFTNHNDDSKNSNITTSNDSPVNEVEPMAPELSSAVVEKKEPEDYESISAVDENTNDSNESLPSSHDYSESTKENSAPDSLLLGLVLDELVFSTTSTTPLPALSHLFPSNMPLQLIQDKLRDLAAKHPYFEEVKRYGTDANGDPLWSEWFYNPDVDDDLERRMRYAPLMRPVRSSRRVHKQYYWKKPRARPRSSGHSSRRRRLS
Protein: Ubiquitin-like protein ISG15 (L5LC70)
Organism: Myotis davidii (David's myotis)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
Sequence:
MLSNEFQVPMRDSMLLSELKQLITQKIQVPAFRQRLLVQGSNEVLQDGVPLAHQGLRSGSEVVLVVQSCDRPLSILVRNDRGNNRAYEVQLTQKVARLKEQVAERESTNVDQFWLSFQGQPLDDEKQLGEYDLTPHCTVQMNLRLRGGEEGLGGQR
Protein: 1,4-beta-xylanase (O05775)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MHRRTALKLPLLLAAGTVLGQAPRAAAEEPGRWSADRAHRWYQAHGWLVGANYITSNAINQLEMFQPGTYDPRRIDNELGLARFHGFNTVRVFLHDLLWAQDAPGFQTRLAQFVAIAARYHIKPLFVLFDSCWDPLPRPGRQRAPRAGVHNSGWVQSPGAERLDDRRYASTLYNYVTGVLGQFRNDDRVLGWDLWNEPDNPARVYRKVERKDKLERVAELLPQVFRWARTVDPVQPLTSGVWQGNWGDPGRRSTISAIQLDNADVITFHSYAAPAEFEGRIAELAPLQRPILCTEYLARSQGSTVEGILPIAKRHNVGAFNWGLVAGKTQTYLPWDSWDHPYRAPPKVWFHDLLHPNGRPYRDGEVQTIRKLNGMPSQD
Protein: GPI-anchored protein 13 (Q5A343)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Cell wall protein which contributes to cell wall synthesis and is important for acquiring normal surface properties. Required for virulence in a mouse infection model.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:22343036}. Membrane {ECO:0000269|PubMed:22343036}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:22343036}. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Interaction partners:
Sequence:
MRSPSLAVAATTVLGLFSSSALAYYGNTTTVALTTTEFVTTCPYPTTFTVSTCTNDVCQPTVVTVTEETTITIPGTVVCPVVSTPSGSASASASAGASSEEEGSVVTTQVTVTDFTTYCPYPTTLTITKCENNECHPTTIPVETATTVTVTGEVICPTTTSTSPKESSSEAASSEVITTQVTVTDYTTYCPLPTTIVVSTCDEEKCHPTTIEVSTPTTVVVPGTVVCPTTSVATPSQSEVATKPTTINSVVTTGVTTTDYTTYCPSPTTIVVSTCDEEKCHPTTIEVSTPTTVVVPGTVVHPSTSATIITTTAEQPPASPEVSTIESVVTTPATLTGYTTYCPEPTTIVLTTCSDDQCKPHTVSATGGETVSIPATIVVPSSHTTQVEITVSSASVPASEKPTTPVTVAAVSSSPAVSTETPSLVTPAISIAGAAAVNVVPTTAFGLFAIILASIF
Protein: Golgi to ER traffic protein 1 (Guided entry of tail-anchored proteins 1) (Mitochondrial distribution and morphology protein 39) (P53192)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in mitochondrial distribution and morphology.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion membrane {ECO:0000269|PubMed:16823961}; Multi-pass membrane protein {ECO:0000269|PubMed:16823961}.
Interaction partners:
- ATPase GET3
- Golgi to ER traffic protein 2
- Golgi to ER traffic protein 4
- Ubiquitin-like protein MDY2
- Small glutamine-rich tetratricopeptide repeat-containing protein 2
- SRP-independent targeting protein 2
- ER membrane protein complex subunit 3
- Mitochondrial inner membrane protein OXA1
- ER membrane protein complex subunit 6
- Protein transport protein SEC61
Sequence:
MHWAAAVAIFFIVVTKFLQYTNKYHEKWISKFAPGNELSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSENKAFQAHLHKLRLLALTVPFFVFKIMYGKTPVYKLSSSTSTLFPTFVSGVWSQGWLYVLLHPLRTISQKWHIMEGKFGASKFDDMALQSVSLGIWVWALMNVINGVEFIVKQLFLTPKMEAPASVETQEEKALDAVDDAIILD