wanglab/gogpt-training-data huggingface dataset:
Protein: NAD-dependent protein deacetylase Sir2B (PfSir2B) (EC 2.3.1.286) (Regulatory protein SIR2 homolog B) (SIR2-like protein B) (Q8IKW2)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Regulates the expression of the surface antigen-coding var genes central to the malaria pathogenesis. Cooperates with Sir2A to mediate silencing and mutual exclusive expression of only 1 of the 60 subtelomeric var genes at a time, coding for functionally different but epitopically variant versions of the erythrocyte membrane protein 1 (PfEMP1) molecule, to evade the detection by host immune surveillance.
Interaction partners:
- NAD-dependent protein deacylase Sir2A
- 3'-5' exonuclease
Sequence:
MSCMNYASRLSKNEYKGPLGEEEFFEDTEEEKKKVKELIEKIRSSEYIVVHSGAGISTSSGLQDFRGPTGIWTNEHLNELKNKKKRNHDFKDNKRKLKSNDINCKNTSDMCSPSFFHKEKKENTLNIVKRERYYNEDNVDMNACNERVVHPNHVYVNHEDDNNNNNNNNNNDNNLYNNVYNSVGSNDHTNKESILIKKENNSENVRKDIHDKVNTKNVKKIDVKETNNLDPENYVIFGKRKKKVIELHLALPSKTHIMINELINKNIIKFMITQNIDSLHHRCGKHFSKTAEIHGNIFTERCDFCGRRYLRDYLISTISFKPTGSLCFLCSFPPIGVCTDVLLDWNNSYEEFFHLNSIKHSQIADFHFCLGSSFYIVPASSYPSKKKYANANSYSCVINYQKSFLSKEVNLNIHSNVNNISDIIIKEFSLNPLSIRSARITIVRCPINTLDVICDKLISIHNIKMKHKSMRQHSIDYSQMGNKDEKYNNEKYVKRNMTECLYYNKEGECYEKRKYKLMEKKFFPNNQQNEFIPNRINIFEQKFHEHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSSIDSSCSINSNYHISKNINPDFSFVENQSNIYENYKEQTFILICPMIINIKTVRLESFHKVYIKLLDDIKGLWFIKTNFSCILEVELWYHSFILLKLDFNKSDPFIQLNAWNVNVAYTYGDDIDDFDYFKNDENIKKPFNLYKNKYISNMRREGHVNNLYTLDNEKVKSNTSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNNNNNISDHNIYDDHNNNNNKNHNNYDKDNSNESYYCSEILNEHVHVGYNPNNYEPNCKVYILAYLDNLRTRNINNNVNNNNFSRFNLTQSCKLLYNIYCVLNKDNEQKKNSTIKETYDKLDYFIKNFDFNRDSCLYTNNFINMLIQNERHGNQSRYKFRERRKRLLNDYSSCSSDDDQSGKNIFIFYNLYMNQYKKKEDNEINDIYKKYDVHEKNIYDESKQYVHKVRVRTDLINHKSVYKILKNNYLVNINNMKLMEKKNNSEKLFLINDKDNNSLLSINNKENFNCIPSRQNNVKKNSEYMHEEENNKTNSNENIARLNNNDFIQVMETEKQKKYNSFDKYNSDRSSINDTFDEIKYNKNNDNNNDDNNYDDNKNDDDNNNDDNNNNDDNNNNDDNNNNDDNNNGYIYSPVLFINKKFKLGELVYKIPKYVKPQKIYTPYKKISRNKKYSNTLQKDRYEKWKMLYEELINNENKTYIIDSVLYKEISYLPYWILNYVNDLFECM
Protein: Phosphatidylinositol 5-phosphate 4-kinase, isoform A (EC 2.7.1.149, EC 2.7.1.68) (Phosphatidylinositol 5-phosphate 4-kinase, isoform B) (RH07911p) (Q8SXX1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Phosphatidylinositol 4-kinase beta
- Phosphatidylinositol 4-kinase alpha
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- phosphatidylinositol 3-kinase
- EG:86E4.5 protein
- phosphoinositide 5-phosphatase
- Phosphatidylinositol-3-phosphatase SAC1
- Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform E
- Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl
Sequence:
MEKKISSSSQPRILKKKHFRVKHQKVKLFRANEPILSVFMWGINHTINELSHVNIPVMLLPDDFRAYSKIKVDNHLFNKENMPSHFKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKSLTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFDLKGSTVDREASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSLLVGVHDCVRAEEEALQGDNILTVGRSENSESEECDSGERWTYNTPPDSPRGAQYKEVVYEVDIYDIPSIEEKREIYFIAIIDVLTQYGVKKQAAKAAKTVKYGSNVDGISTCDPEQYAKRFLDFMDKAIE
Protein: Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR) (Q923M1)
Organism: Rattus norvegicus (Rat)
Function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
Subcellular location: [Isoform 1]: Mitochondrion.; SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion.; SUBCELLULAR LOCATION: [Isoform 3]: Mitochondrion.; SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm.
Interaction partners:
- Methionine-R-sulfoxide reductase B2, mitochondrial
- L-methionine
- Thioredoxin
- Methionine-R-sulfoxide reductase B1
- Thioredoxin, mitochondrial
- Thioredoxin domain-containing protein 3
- Superoxide dismutase, mitochondrial
Sequence:
MLSASRRTLQLLSSSIPVRMMGDSSSKVISAEEALPGRTESIPVAAKHHVSGNRTVEPFPEGTQMAVFGMGCFWGAERKFWLLKGVYSTQVGFAGGYTRNPTYKEVCSEKTGHAEVVRVVYRPEHVSFEELLKVFWENHDPTQGMRQGNDCGTQYRSAVYPTSAVQMEAALKSKEEYQKVLSKHGFGPITTDIREGQVFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPTAIKK
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (F1QZR2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Cell division control protein 42 homolog
- Rho guanine nucleotide exchange factor
- Rho guanine nucleotide exchange factor
- Mitogen-activated protein kinase kinase 1
- Raf-1 proto-oncogene, serine/threonine kinase b.
- Raf-1 proto-oncogene, serine/threonine kinase a.
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
- Cell division cycle 42-like 2
- Cell division control protein 42 homolog
Sequence:
MFSKKKKQRIQISAPSNFEHRVHTDFDEQEQKFVGLPRQWQSLIEDTAKRPKPFIDATVITTVEPRKTIVRGRKIGDDGSLTWLLDEFETMSVIRSNSLRRGSPPLQPRSDSGSSGGHENGEHPQYRHTDRYGDSKEREKPRQEHPGTDPRQSQRPGRSSREDGRPQQQPRGQEPSRHKEPDWITPGQHREREWDREREPRDYSDHVVRREGANDKRPKSSYTGRDSSPQSPREKRPLSGPNIRTPNLPVTEGVIKAAQQTGRPFNTYPRSESDSGRTPSGQDLKPAKSHESTHHNGPSAGPVRGGSSSSSSGGGQTSSQGPHRSEPQHHASHPALGPEPPHGQPMPPPPKPSGPAAPSQPTRSPQREPQRVSHEQFRAALQMVVDPGDPRTYLDHYIKIGEGSTGIVCIATVKTTGKLVAVKKMDLRKQQRRELLFNEVVIMRDYHHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQISTVCLSVLKALSVLHSQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVQRRKSLVGTPYWMAPELISRLPYGPEVDIWSFGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPKLKNLHKVSPLLKGFLDRMLVRDPAQRATAQELLKHPFLTKAGPPSCIVPLMRQNRMR
Protein: Coatomer subunit beta (Beta-coat protein) (Beta-COP) (P45437)
Organism: Drosophila melanogaster (Fruit fly)
Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets.
Subcellular location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity). Present within the clusters of tubulo-vesicular structures of Golgi membrane and cis-Golgi membranes. {ECO:0000250}.
Interaction partners:
- Coatomer subunit alpha
- Coatomer subunit gamma
- Coatomer subunit zeta
- Coatomer subunit delta
- Coatomer subunit beta'
- Coatomer subunit epsilon
- ADP-ribosylation factor GTPase activating protein 3, isoform H
- ADP-ribosylation factor 1
- Protein transport protein SEC23
- General vesicular transport factor p115
Sequence:
MTSQVPCYTIINSPDLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVLPVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIASFLDTQQDMSCKRNAFLMLLHADQERALNYLASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLNSSSNAVRYESAGTLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMDVLRVLAAPDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNVEHEDTGKYRQLLVRTLHTCSIKFPDVAANVIPVLVEFLSDTNELAAADVLIFIREAIQKFPALRALIIEHLIEAFPQIKSSKIHRAAVWILGEYVEGSQILEVIAVIQQTLGEVPMVEAEQRRLAGDQTEEQKQQQGSAGGNAAGSAAEGSGSGNASNKVTSDGTYATQSAYSLAPVAKAEKRPPLRQYLMDGDFFIGAALSATLTKLALRYAELETEARAQNRLTTQVMLIMSSILHLGKSGFPSKPITNDDTDRIFVCLRTLSERTPEAISVFTLYCREALGKMLDAQHDEDQRMLKEKQKATAKVQPDDPVLFAQLSNGRDNQLGENVFESSLNQALAGSKNAQLSDVASPNSKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQNCTLELATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVYETALNTNVVVLNTIHIDIMDYIIPASCTDTEFRQMWQDFEWENKVTVNTSFTDLHEYLKHLLKSTNMKCLTPEKALSGQCGFMAANMYAKSIFGENALANLSIEKPVDDPDSKVTGHIRIRAKSQGMALSLGDKISSSQKQSVQAA
Protein: Myoneurin (Q99MD8)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000269|PubMed:14694499}.
Interaction partners:
- Leucine-rich repeat-containing protein 34
- Leucine-rich repeat and IQ domain-containing protein 4
- Actin-related protein T3
Sequence:
MQYSHHCEHLLERLNKQREAGFLCDCTVVIGEFQFKAHRNVLASFSEYFGAIYRSTSENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAFIASPSSTEISSITGNIELNQQACLLTLRDYNNREKSEVSTDSVQANPKPRALTKKSSQSKKKKKAFSSQKPGQSKAVQYPSDVLESASVELFLETSKLSSPVVEQIIQGNDSSELELTSVVENTFPTQDIVQTVTVKRKRRKSQSHCALKEHSMSNIASVKSPYELENAGEELDARFSKAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVRTHTGERPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGERPFICELCGNSYTDIKNLKKHKTKVHSGTDKNPDCSVDDHAVSEQDSVQRSPLSETLDVKPSDMTLPLALPLGTEDHQMLLPVTDSQSPASDTLLRSTVNGYSEPQLIFLQQLY
Protein: Ring finger and CHY zinc finger domain containing 1 (A0A8I5ZWY8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAATAQEDGVRSPAPGPRGCEHYDRACLLKAQQTCEDCSTLFGEYYCSICHLFDKDKKQYHCESCGICRIGPKEDFFHCLKCNLCLAMTLRGKHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDIEVAQTPMPSEYQNVTVDILCNDCNGRSTVQFHILGMKCKLCDSYNTAQAGGRTVSMDEQ
Protein: Casein kinase II subunit beta (CK II beta) (Q383J7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- FACT complex subunit
- Nrap protein domain-containing protein
- ATP-dependent RNA helicase
- Small-subunit processome Utp21 domain-containing protein
- Glycogen synthase kinase 3
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- KRR1 small subunit processome component
Sequence:
MNYPMYVGEYSDDRTGFDEEVDEEVIPWIVWFCEMKSHEFFCVVDRDFIDDEFNLTGLSSMVSFYHYALDLILDLETQSSSRLTEEQQRLVESSAETLYGLIHARFITTPRGLKLMEEKFVEGEFGRCPRVFCGGQAVLPVGQSDVVRESSVKLFCPKCQDIYYPRSSRHRALDGAFWGTTFPHLFLMHLRENGKVIGRPKQQYIPRIYGFRLHNKEKCVRDEDVERAGSVGGGAAGADEGDAEEEEEQEEEEGSHHQQQIGGEGSTRQNTPNSRKGRSGARGPRGEPEETPKR
Protein: Cysteine-rich receptor-like protein kinase 19 (Cysteine-rich RLK19) (EC 2.7.11.-) (Q8GWJ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- CDPK-related kinase 5
- CDPK-related kinase 7
- Protein MODIFYING WALL LIGNIN-1
- Protein MODIFYING WALL LIGNIN-2
- CDPK-related kinase 2
Sequence:
MSSLISFIFLFLFSSITASAQNTFYLYHNCSVTTTFSSNSTYSTNLKTLLSSLSSLNASSYSTGFQTATAGQAPDRVTGLFLCRVDVSSEVCRSCVTFAVNETLTRCPKDKEGVFYYEQCLLRYSNRNIVATLNTDGGMFMQSARNPLSVKQDQFRDLVLTPMNLAAVEAARSFKKWAVRKIDLNASQSLYGMVRCTPDLREQDCLDCLKIGINQVTYDKIGGRILLPSCASRYDNYAFYNESNVGTPQDSSPRPGKGGNSSVIIIAVVVPITVLFLLLVAVFSVRAKNKRTLNEKEPVAEDGNDITTAGSLQFDFKAIEAATNCFLPINKLGQGGFGEVYKGTLSSGLQVAVKRLSKTSGQGEKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFVPNKSLDHFLFDSTMKMKLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLDDDMNPKIADFGMARIFGMDQTEAMTRRVVGTYGYMSPEYAMYGQFSMKSDVYSFGVLVLEIISGMKNSSLYQMDESVGNLVTYTWRLWSNGSPSELVDPSFGDNYQTSEITRCIHIALLCVQEDAEDRPTMSSIVQMLTTSLIALAEPRPPGFFFRSKQEQAGPSIDSSTHCSVDEASITRVTPR
Protein: Signal transducer and activator of transcription (B0S790)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
Sequence:
MSQWKQVQQLDIKFLEQVDYFYDDNFPMELRQVLANWIESQDWETASNHESMATVLFNNFLIQLERQCSQEQNFLHRHNLKRIFHQIQVKYKANPLQMAAVICNCLREERRILSTASMQEQGPLEKSMQNSAALEKQKVLDNKVAVIRSSVQMLDQAVKYLEDMQDDFDFRYKTLQLRDPLERNSSSMKQEVTTLQEILNRLDFKRKEFLSKTADVIKEIDALISSQLNPELKEWKRRQQIACIGGPVLIGLDQLQNWFTLTAQSLFQIKRQLDKLGELILKVTYESDPIPLQRPQMEEQVKYLIYHLIKSSFVVEKQPCMPTHLQKPLIIKTQVQFTTKVRLLVKLPEVDYQLKVKTTFDKDLPPGKVNRQFFILTNNTKVMDVEESTGCLSVEFRHLLKERKCPTGGKGNEGPLSVTEELHSLNFEAMLMLQGLDIDLETCSLPLVVISNVSQLPGGWASVMWYNLLTDDPKNLAFFSNPLRASWSQLSEVLSWQFSSFAGRGLNKEQLNMLGDKLLGQHGSYNDCQVSWSKFCKEVIPGKSFSFWMWLDSILDLIKKHLLPVWIDGCIMGFVSKEMERALLKEKEPGTFLLRFSESHLGGITFTWVEQDENGDPKFISVEPYTKNRLNALPIADIIRDYKVIADGVVPENPLNFLYPDIPKDEAFGKHYNSQQNKVCPYIPTHLVPISHRVPAQHSCSSPEPPMSPGMYEIITQHLSPFEFESAMSSP
Protein: Heparin-binding fibroblast growth factor receptor 2 (Q63242)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
ITSVQMGLTSTWRYGTGPGIGTVTMVSWGRFICLVLVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDSSEDFVSENRSNQRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPVREKEITASPDYLEIAIYSIGVFLIACMVVTVIFCRMKTTTKKPDFSSQPAVHKL
Protein: Nitrous-oxide reductase (EC 1.7.2.4) (N(2)OR) (N2O reductase) (P19573)
Organism: Stutzerimonas stutzeri (Pseudomonas stutzeri)
Function: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
Subcellular location: Periplasm.
Interaction partners:
Sequence:
MSDKDSKNTPQVPEKLGLSRRGFLGASAVTGAAVAATALGGAVMTRESWAQAVKESKQKIHVGPGELDDYYGFWSGGHQGEVRVLGVPSMRELMRIPVFNVDSATGWGLTNESRHIMGDSAKFLNGDCHHPHISMTDGKYDGKYLFINDKANSRVARIRLDIMKCDKMITVPNVQAIHGLRLQKVPHTKYVFANAEFIIPHPNDGKVFDLQDENSYTMYNAIDAETMEMAFQVIVDGNLDNTDADYTGRFAAATCYNSEKAFDLGGMMRNERDWVVVFDIHAVEAAVKAGDFITLGDSKTPVLDGRKKDGKDSKFTRYVPVPKNPHGCNTSSDGKYFIAAGKLSPTCSMIAIDKLPDLFAGKLADPRDVIVGEPELGLGPLHTTFDGRGNAYTTLFIDSQVVKWNMEEAVRAYKGEKVNYIKQKLDVHYQPGHLHASLCETNEADGKWLVALSKFSKDRFLPVGPLHPENDQLIDISGDEMKLVHDGPTFAEPHDCIMARRDQIKTKKIWDRNDPFFAPTVEMAKKDGINLDTDNKVIRDGNKVRVYMTSMAPAFGVQEFTVKQGDEVTVTITNIDQIEDVSHGFVVVNHGVSMEISPQQTSSITFVADKPGLHWYYCSWFCHALHMEMVGRMMVEPA
Protein: COBRA-like protein 11 (Protein POLLEN SPECIFIC GENE 4) (Q9T045)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the deposition of apical pectin cap and cellulose microfibrils in pollen tubes. Implicated in pollen tubes growth in the female transmitting tract of pistil and toward micropyles, via the perception of ovule guidance cues.
Subcellular location: Cell membrane {ECO:0000269|PubMed:23384085}; Lipid-anchor, GPI-anchor {ECO:0000255}. Note=Localized at the apical plasma membrane of pollen tubes (PubMed:23384085). In the cytoplasm, observed in motile punctate vesicles (PubMed:23384085). {ECO:0000269|PubMed:23384085}.
Interaction partners:
- Probable inactive nicotinamidase At3g16190
- Nicotinate phosphoribosyltransferase 1
- Nicotinate phosphoribosyltransferase 2
- Nicotinamide adenine dinucleotide transporter 2, mitochondrial
- Nicotinamidase 1
- Glutamine-dependent NAD
- Nicotinamide adenine dinucleotide transporter 1, chloroplastic
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase
- NAD kinase 2, chloroplastic
- NAD
Sequence:
MKKLRYVHLNLLLLLLPLINLQFPTLSLAQDYDEPKKDDTPPPGLARCNGVYMSYSSGGREKLYPRTTNATAQAWSFKSTAMIVNTGIEEVKGWQMFVGFHHREIIVSATGAVSSDGDFPVDATNGTTFIGSQNTDLKTSILTAGDYTQISTNIEITGTVFGGKGTATPMPKSIKLTNDGWQCPAATSKGGTMQVCCKRNPKFKAKEKVKTKFMPRQHGDLNIIYDVLQAYASSYMAQVTIDNTSPLGRLDHWNLTWEWMRGEFIHSMRGAYAAEKNTLECLSSKAGQFYGDLDFSQVANCQKKPIIKDLPAERKDDNVTGKLPFCCKNGTLLPTHMDPSKSKAIFQLQVYKVPPDQNRTAFFPPRNWKIDGIVNPTYKCGPPIRVDATPFPDPSGLQATTYAIASWQVICNITKPKPQAARCCVSFSAFYNDSAIPCNTCACGCKDIDTDTCNANARQLLLPTDTLLVPFDNRTLKAKVWAKQKHMAYPKKLPCPDNCGISLNWHLNSDYGNGWSARVTLFNWGNNAVEDWFGALDLGKAGLGYENIYSFNGSRVPPKNQTIFFQGLPGMNYLIGITNGTNPARDPQIPGKMQSVISFKKKNLGSLNIIGGDGFPKRVFFNGEECELPKYFPKKSSGMRLSGIRFLPSILLAITTFHAITDRLLTGV
Protein: V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) (P50516)
Organism: Mus musculus (Mouse)
Function: Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity). May play a role in neurite development and synaptic connectivity (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23863464}. Cytoplasm, cytosol {ECO:0000269|PubMed:31786107}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P38606}. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:P31404}; Peripheral membrane protein {ECO:0000305}. Lysosome {ECO:0000269|PubMed:31786107}. Note=Co-localizes with WFS1 in the secretory granules in neuroblastoma cell lines. {ECO:0000250|UniProtKB:P38606}.
Interaction partners:
- V-type proton ATPase subunit D
- V-type proton ATPase subunit C 1
- V-type proton ATPase 16 kDa proteolipid subunit c
- V-type proton ATPase subunit E 1
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase subunit F
- V-type proton ATPase subunit B, brain isoform
- V-type proton ATPase 116 kDa subunit a 1
- V-type proton ATPase subunit G 2
- V-type proton ATPase subunit H
Sequence:
MDFSKLPKIRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTYIAPPGNYDASDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED
Protein: External NADH-ubiquinone oxidoreductase 2, mitochondrial (EC 1.6.5.9) (External NADH dehydrogenase 2) (Q07500)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: External NADH dehydrogenase required for optimum cellular growth with a number of nonfermentable carbon sources, including ethanol. With NDE1, performes the mitochondrial oxidation of cytosolic NADH under these growth conditions. Regulates the mitochondrial glycerol-3-phosphate dehydrogenase, GUT2, also involved in cytosolic NADH oxidation.
Subcellular location: Mitochondrion intermembrane space {ECO:0000269|PubMed:14576278}.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- D-lactate dehydrogenase [cytochrome] 1, mitochondrial
- L-lactate dehydrogenase
- External NADH-ubiquinone oxidoreductase 1, mitochondrial
- 6-phosphogluconate dehydrogenase, decarboxylating 2
Sequence:
MLPRLGFARTARSIHRFKMTQISKPFFHSTEVGKPGPQQKLSKSYTAVFKKWFVRGLKLTFYTTLAGTLYVSYELYKESNPPKQVPQSTAFANGLKKKELVILGTGWGAISLLKKLDTSLYNVTVVSPRSFFLFTPLLPSTPVGTIEMKSIVEPVRSIARRTPGEVHYIEAEALDVDPKAKKVMVQSVSEDEYFVSSLSYDYLVVSVGAKTTTFNIPGVYGNANFLKEIEDAQNIRMKLMKTIEQASSFPVNDPERKRLLTFVVVGGGPTGVEFAAELQDYINQDLRKWMPDLSKEMKVILIEALPNILNMFDKTLIKYAEDLFARDEIDLQVNTAVKVVEPTYIRTLQNGQTNTDIEYGMLVWATGNEPIDFSKTLMSRIPEQTNRRGLLINDKLELLGSENSIYAIGDCTAHTGFFPTAQVAHQEGEYLAKILDKKLQIEQLEWDMLNSTDETEVSRLQKEVNLRKSKLDKFNYKHMGALAYIGSETAIADLHMGDSSYQLKGMFAFLFWKSAYLAMCLSIRNRILIAMDWTKVYFLGRDSSV
Protein: Cuticle collagen dpy-2 (Protein dumpy-2) (P35799)
Organism: Caenorhabditis elegans
Function: Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-2 affects the body shape.
Interaction partners:
- LiPocalin-Related protein
- Cuticle collagen dpy-7
- Leucine-rich repeat-containing protein let-4
- NOmpA Homolog
- LiPocalin-Related protein
- Fungal lipase-like domain-containing protein
- YitH/HolE acetyltransferase
- WaRThog
- Apple domain-containing protein
- dTDP-4-dehydrorhamnose 3,5-epimerase
Sequence:
MKSQTSGYVDPQTEEYDESREKSYQVLIAVSGVLSITSLLILVLFVPSMYNYVDNISRFSRRDFEFCQASANDLETEMMSVREGLLRGRNVTKRAAGYGHYNPSMLAADSPQFQECPACCIPGERGPSGDSGLPALPGAPGPDGAPGRPGTTPNASCIPERVFEPPPCLPCPQGPRGVPGHPGFPGDPGEYGIGGRPGSDGMPGKPGDPGLAGPIGPPGESGPIGDKGRTPEAHVIPGPPGDSGLPGPWGPPGSAGMPGEDGYAGTPGEKGWPGPPGAPGPGGMPGPNGPTGEQGPSGTPGTCVCQDTEVVMNDEKGRVPAPRDNVAPGATGGSYEPQGGNDAAAPSAISQSQNRRIRKW
Protein: Interleukin 4 receptor (Q5EAS6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MSSSLFLYQIILTLVCQALCDDPIKDFNCFNDYEAEMTCSFSSESLRNCSGYNMNVTQKLAYEINRYSCVFEGSHHNAICECKIEVEGFITEEIFSTTLLKGTKVLLQRDFKTIDYIKPKTPVLFVKKTENGNFHVTWVDSYEQRNVFTDNLFITLTYRIKGEIETNSTKVANTVGFCDIVGSLLQPKTEYILTAKMSSNYNGQKIYSDQSAAVHFTTGL
Protein: Topisomerase II associated protein (Pat1), putative (AFU_orthologue AFUA_5G10770) (Q5B9M9)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm, P-body {ECO:0000256|ARBA:ARBA00004201}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm5
- U6 snRNA-associated Sm-like protein LSm2
- U6 snRNA-associated Sm-like protein LSm3
- U6 snRNA-associated Sm-like protein LSm6
- Small nuclear ribonucleoprotein
- U6 snRNA-associated Sm-like protein LSm4
- Decapping enzyme Dcp2, putative
- ATP-dependent RNA helicase DHH1
- poly
- Enhancer of mRNA-decapping protein 3
Sequence:
MSFFGFDTTLPRDRAPQGGQRGIFDTPDPFAEVARARAAAQHEDDDDVLNFEDTYDGLGDQLDDDQDAFNEDTFGDVGSGPVGKDFDFFGKTAQVSDVIGEEQVRYNLKNPQASVAPRATEPQKTATTTAQQPKRTGYEKYSDPDYIPDLQAKSSVWGLPSKPESAPQATTQTKKMMSLEEVEAQIRNQGAAAPGFGPQVSLPQHVPEPPLPLQRPPGLPEGFPQLPPEYLEAQFGRGVPPQFLHPRTIAPEPFPHPAQAPNIPLHLLQNPIQNPNAPPSHMGPLQHQAIPSRDQPPQRLPQQHLPQHGRGLSAGLPLITNPQQLMNLTEEQRVAYLMEDAKRAKRNHKIFLLSKGNGLMTPQDKNFITRIQLQQLVAQAGNMADTDSDAVLAEDFYYQVYSQIRGAPRQHPHQPLGHFAQTYLLQTGNRIGGHSRKHGQSADNHMQRMQQQVQRAVEAAKAKPKNKQLIIEGSLGKISFGNAKAPKPSLNIKRPESSEGGKATKKLPTDLSPSDRKSILANLEGVYNTLMELEDMARTMPPPPDENDSEAIQTHMEWRQKLNALNQKLWNQMKVMEAIVPNSNTPHPFIALLSYPKGKKAIPRIFRHIDQEQRITILTMIVVNLDNLDVVRRALPAPGEAQPPLAAREAIDLFSQAVMPCLLGYVNEAPFNIIIGLLGLVLTHTHAQFVARTRIGLGILTMLLSRAEIVKEAGQASEQDWKQWVEKFNILFDTLEPTFADIFPNSINAGDDMYVWQFLAAIGIGASPEQQQRLVIAVKDRVMETVTHSKTLPADMASQRLGNVNLFMRAIGLDVELLG
Protein: Insulin-like growth factor I (M1T4V2)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU000406}.
Interaction partners:
Sequence:
MEKINSLSTQLVKCCFCDFLKVKMHTVSYIHFFYLGLCLLTLTISAAAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRLHHKGIVDECCFQSCDLRRLEMYCAPIKPPKSARSVRAQRHTDMPKAQKEVHLKNTSRGNTGNRNYRM
Protein: K-box region and MADS-box transcription factor family protein (F4KB90)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRGRVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEVALIIFSNRGKLYEFCSSSNMLKTLDRYQKCSYGSIEVNNKPAKELENSYREYLKLKGRYENLQRQQRNLLGEDLGPLNSKELEQLERQLDGSLKQVRSIKTQYMLDQLSDLQNKEQMLLETNRALAMKLDDMIGVRSHHMGGGGGWEGGEQNVTYAHHQAQSQGLYQPLECNPTLQMGCCFGDDDDDDRYDNPVCSEQITATTQAQAQQGNGYIPGWML
Protein: Protein Malvolio (P49283)
Organism: Drosophila melanogaster (Fruit fly)
Function: Putative transporter required for normal taste behavior. May be a nitrite/nitrate transporter.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- FI03373p)
- Multicopper oxidase 3
- Mitoferrin
- P-type Cu
- Proton-coupled zinc antiporter SLC30A9, mitochondrial
- Zinc transporter ZIP13 homolog
- Ferritin
- Superoxide dismutase
- LD23375p
- Cytoplasmic aconitate hydratase
Sequence:
MSSNEAYHEPGAGGDGPGGSSGASGGGSQRSNQLHHQQILNETTYLKPAAKQAYFSDEKVLIPDDDSTNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVENMEIKGGLLALVCIFAILYILFNLYLVIHMAACMGNQRLMNSRWVQRFVLPSQNSFSIKNANSTYARIATSSDQEPEGLAGEDA