wanglab/gogpt-training-data huggingface dataset:
Protein: Filamin B (A0A0G2JXT8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Talin 1
- Talin 2
- Vinculin
- Integrin beta
- Filamin, alpha
- Integrin beta-1
- Dual specificity mitogen-activated protein kinase kinase 4
- Ubiquitin-like protein ISG15
- Serine/threonine-protein kinase PAK 1
- Filamin-C
Sequence:
MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIESTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNSVELLVEDRGNQVYRCVYKPLQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELAVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKTGCTINNPAEFIVDPKDAGNAPLKILAQDGEGQPIDIQMKSRMDGTYVCSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASEEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPVPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGSYAVTYVPLTAGMYTLTMKYGGELVPQFPTWVKVEPTVDTSGIKAFGPGIEGKDVFREATTDFTVDARPLTQVGGDHIKAHIANPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDAPIPNSPFKVAVNEGCQPSRVHAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDTSKAGLAPLEVRVMGPRGLVEPVDVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGQVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEAGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLISVKYGGPNHISRSPFKAKVTGQRLVTPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKEKGDYVLAVKWGEEHIPGSPFHVTVP
Protein: Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)] (O95396)
Organism: Homo sapiens (Human)
Function: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03049, ECO:0000269|PubMed:15073332, ECO:0000269|PubMed:23593335}.
Interaction partners:
- Molybdopterin synthase catalytic subunit
- Ubiquitin-related modifier 1
- Thiosulfate sulfurtransferase
- Cysteine desulfurase
- 3-mercaptopyruvate sulfurtransferase
- Cytoplasmic tRNA 2-thiolation protein 1
- Molybdenum cofactor biosynthesis protein 1
- Cytoplasmic tRNA 2-thiolation protein 2
- Elongator complex protein 3
- Elongator complex protein 4
Sequence:
MASREEVLALQAEVAQREEELNSLKQKLASALLAEQEPQPERLVPVSPLPPKAALSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTDLLDYEAFCGSSATDKCRSLQLLSPEERVSVTDYKRLLDSGAFHLLLDVRPQVEVDICRLPHALHIPLKHLERRDAESLKLLKEAIWEEKQGTQEGAAVPIYVICKLGNDSQKAVKILQSLSAAQELDPLTVRDVVGGLMAWAAKIDGTFPQY
Protein: Dfg16p (Q5AHB5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- pH-response regulator protein palH/RIM21
- pH-response regulator protein palI/RIM9
- pH-response regulator protein palF/RIM8
- Calpain-like protease palB/RIM13
- pH-response transcription factor pacC/RIM101
Sequence:
MGCSIYHLNTGVISLLDYFNKTWVNQSTAILPAYYITNCSVEDMLSYNNITSDPKYLAFDYSPYNKRDNGDTYVALLFVLSGSCVSMWMLSLLLYLSPKYKRKPLLTQLATVFYAIITTFFLNKLTRASEKQYYEDVLDIVELHTILYNNVEYRVLIIIFQVLLLLSWFQIIQKLAKQKYKRIIAIVTGVLMAAFSGCFIYYQVEYNTEGRIHMENISGLYLRWKVVRSVMKLILVLWFAGNLLYYTTVVKNPRKICYCKKLLPLAIFNWFLLILHIILGILHISLFEDNWLVRTWMVLIPYLIEAILITTVWEWIFNIWVIEKRIELMGVLGRRISIDDVLSIQSLRGNNTRKGEKTFTKNGSSSDSGGFHGRSGTRKPMAKFQNWIMNRPKRVTTESEILSNNDINELKEFSTFSNSSSNNDPSQRNSNSQLQNQTQQVNTMQRNNDQILQQHNNLHLQNLDTDSAASSSQSQALALHTEDDDVEYDDEYVDDYEIWDDDEDEEEEEEISHHQRVSSTHLVGSTVEENDMHLGSSNNRHGSGDHMDLPPAFQPHPGFEAGDYWNDRKEG
Protein: Alanine dehydrogenase (EC 1.4.1.1) (Q6LX40)
Organism: Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL)
Function: Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:A0QVQ8}.
Interaction partners:
- Alanine racemase
- Sodium/alanine symporter AgcS
Sequence:
MLIGVPKEIKNNENRVAITPAGVEAFVLAGHKVYIEKGAGLGSAITDEEYVAAGAEILATAKEVFDTAEMIIKVKEPLKSEFELFKEGQILFTYLHLAPEPQLTKALLDKKITGIAYETVQLADRSLPLLTPMSEIAGRMSIQLGAQYLEKQEGGKGVLLGGVPGVEPAEVVIVGGGIVGTNAAKIAVGMGAKVTILDVNTRRLAYLDDIFGNKVTTLMSNSFNIAKAVKKADLLVGCVLIPGAKAPKLVSEEMVKSMQPGSVIVDVAIDQGGSIETIDRITTHDNPTYEKFGVIHYAVANIPGAVARTSTYALTNDTLPYALQIANKGYKQAVIENPALLKGLNTLNGKVTYEAVAKAHDLPYTPAEKALNE
Protein: Ubiquitin-conjugating enzyme E2 35 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 35) (Ubiquitin carrier protein 35) (Q94A97)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Required for postreplication repair of UV-damaged DNA and for adapting root developmental programs to suboptimal availability of iron.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 variant 1D
- E3 ubiquitin-protein ligase UPL4
- E3 ubiquitin-protein ligase UPL3
- Ubiquitin-conjugating enzyme E2 variant 1A
- Ubiquitin-conjugating enzyme E2 variant 1C
- Ubiquitin-conjugating enzyme E2 36
- Ubiquitin-conjugating enzyme E2 variant 1B
- E3 ubiquitin-protein ligase BRE1-like 2
- E3 ubiquitin-protein ligase BRE1-like 1
- Ubiquitin-activating enzyme E1 1
Sequence:
MANSNLPRRIIKETQRLLSEPAPGISASPSEDNMRYFNVMILGPTQSPYEGGVFKLELFLPEEYPMAAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLSENIAKHWKSNEAEAVDTAKEWTRLYASGA
Protein: Augurin (Esophageal cancer-related gene 4 protein) (ECRG4) (Q9H1Z8)
Organism: Homo sapiens (Human)
Function: Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:21349154}. Cytoplasm {ECO:0000269|PubMed:21349154}. Apical cell membrane {ECO:0000269|PubMed:21349154}.
Interaction partners:
Sequence:
MAASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPRSPYGFRHGASVNYDDY
Protein: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.-) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nudix hydrolase 4) (Q9U2M7)
Organism: Caenorhabditis elegans
Function: Asymmetrically hydrolyzes Ap4A to yield AMP and ATP.
Interaction partners:
- Putative nudix hydrolase 2
- CTP synthase
- Inosine triphosphate pyrophosphatase
- Receptor-type guanylate cyclase gcy-15
- Nucleoside diphosphate kinase
- Uroporphyrinogen-III synthase
- Putative nudix hydrolase 1
- adenylate cyclase
- Pyruvate kinase
- Pyruvate kinase
Sequence:
MVVKAAGLVIYRKLAGKIEFLLLQASYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEAKGKPKSVKYWLAKLNNPDDVQLSHEHQNWKWCELEDAIKIADYAEMGSLLRKFSAFLAGF
Protein: Large ribosomal subunit protein uL23 (50S ribosomal protein L23) (P9WHB9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
Interaction partners:
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein bL19
- Large ribosomal subunit protein uL2
- Small ribosomal subunit protein bS18A
- Large ribosomal subunit protein bL34
- Small ribosomal subunit protein uS8
- Small ribosomal subunit protein bS6
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein uL16
Sequence:
MATLADPRDIILAPVISEKSYGLLDDNVYTFLVRPDSNKTQIKIAVEKIFAVKVASVNTANRQGKRKRTRTGYGKRKSTKRAIVTLAPGSRPIDLFGAPA
Protein: Upstream-binding factor 1-like protein 1 (HMG-box preimplantation embryo-specific protein) (HMGPI) (Q3USZ2)
Organism: Mus musculus (Mouse)
Function: Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19915186}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:19915186}. Note=Mainly cytoplasmic from the 4-cell stage to the morula stage. Becomes nuclear at the blastocyst stage. In ES cells, found in both the nucleus and the cytoplasm. {ECO:0000269|PubMed:19915186}.
Interaction partners:
Sequence:
MTSLDNQGLWSEKDILKLLECMEHNIPSDDSREFKKSQADLNWSKVAFGLFSGEMCKQKWMEISYNLRKFRTLTELVQEAKFSFTKKTHKNKILTEHPDRPKRPLTAYLRFYKEQRAKYCQMYPKYSNAQLTKILAEKYRQLPAEIKQRYIMDFKKEKEDFQKKMRQFKKRHPVSGHPKKSVVPQSHPTKVPTKSQGDIKNVKSLVKTESPRTVSSDMKFQGEPRKPPMNAYHKFHQESWSSPELRHLSFRKRWVEISRRWHQVPENEKEHYSNQVKRLQKQYRVKLDLWLKRLSPEEYAAYKEAKATCGKRKNMSMSGGRSSKFGRTEQSSSEKGLQIKPGEVEELLDPGTDSSGTIQGHHDGAQSSRQDFTDDSEEDDSSTSSDSSSTDEDD
Protein: EF-hand domain-containing protein (Q38F99)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSKSSRKITCLLPSASNQSGDKRGELQLKKQGPGEQTANEAITVPDLKLDETVRIREMFTEYINGEYVTTLFDLRVLLSELGVYPSDDEMTLVMTAFENKVSFTNLCRYMRFYKKEFLESNKQRHRSNAAQDECEDTLRAFVSLGGNEDGSGSVLVEDLRQVCRNFGLTIDINEALNGLNESESPLTLRYMEFCNLWKHQSRERGGESGTIRSLSLTDTLYTSGGLDGEASNYIHLLNLLKPHVSNISYEQSTPAICTPLLARGDESDARHSLPKSDEKHLQELKRFLLPSLVGSAEDPDANSYGAQRDDGYQLPSLVQHMTPRADAEERQRPLRQRRTKEAAARRSAGNDDKSHPPTQGGFRAPSPMILSLRNLAAYRQRLQAFAKKKEKSRNRERGKGGHGVSSYYDDDGARI
Protein: Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2) (Q9H329)
Organism: Homo sapiens (Human)
Function: Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells. Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing. May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22006950}. Cell junction, tight junction {ECO:0000269|PubMed:22006950}. Note=Accumulates along apical cell-cell boundaries and is also detected in the cytoplasm in a punctate manner. {ECO:0000269|PubMed:22006950}.
Interaction partners:
- Rho guanine nucleotide exchange factor 18
- Protein kinase C zeta type
- Protein kinase C iota type
- Trace amine-associated receptor 1
Sequence:
MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHPSQPRWHPHSPNVSYPLPSPVLSSSDRLPFGIEENGGTPFLTAASGRHHHQHQHQHQHQHHSNYSLSLTLENKEGPLRSPNSSSKSLTKLSPGTPALFSEAAAHLKKLELETVKAAGPWPPLHININKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQGGKEESPFVNINKKSSLQDASVRSPIPIRVETAQPAVEKPEIKPPRVRKLTRQYSFDEDDLPPDLAEAVGVTTSTTTNTTTAATQVSVPLPSPKVQNVSSPHKSEGKGLLSPGAKSPSDRGGAFTLEPGDLLMDFTEATPLAEPASNPHCAHSRCSPPLSLPMKEETTGVCMYPPIKTRLIKTFPVDTMNPFPDTFTTGPQFTADFRDSKLQCCPGPTSPLIPAATLRPLTETVSTVQTIYTTRKPVSLAASAETLRQELEREKMMKRLLMTEL
Protein: Transmembrane protein, putative (DUF3317) (A8MSB8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MNWVQRKIYLYNVTFGLYMLDWWERYLFNSLVVVLMWFVLYNGTRYFSELFQRHLT
Protein: Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19); Phosphoribosyl-ATP pyrophosphohydrolase (EC 3.6.1.31); Histidinol dehydrogenase (HDH) (EC 1.1.1.23)] (Q5BF83)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- 1-
- histidinol-phosphate transaminase
- ATP phosphoribosyltransferase
- Imidazoleglycerol-phosphate dehydratase
- Histidinol dehydrogenase
- Multifunctional tryptophan biosynthesis protein
- Imidazole glycerol phosphate synthase hisHF
- Histidinol-phosphatase
- tryptophan synthase
- Tryptophan synthase
Sequence:
MATPFLVSYDPASASGGLSLQQIAYFGRVLIKATDLAQAETFIRQNFRLLDIYVDATGISATGDLVDILNAGAAKIFISLDQLNALSEEQSVPSSRLVVYTSSNDQVEAFQKWVVKHIEREEAGLCTDSAVVHSISVKLGLNPEAQLLYRTYSGDVTEDAVKDTMKQGGVSIVPAAALTISREESSGKIQAGSLIAARGVKDQGNGLYATTVTDERGTCLGFVWSSDESIAEALRTGTGVYQSRKRGLWYKGQSSGDVQELIRIGFDCDSDCLVFIVKQIGRGFCHLGTASCFGPYTGLSRLQKTLQARKADAPAGSYTARLFNEPKLTQAKIMEEADELCRAETKEDIAFEAADLLYFALTRCVAAGVSLEDVERNLDLKSLKVKRRKGDAKGPWAEKAGLAEKPAEAKPAPKPEEPKEDTSRIEMTRVATASTPAEKVQEYLKRPSQKSNDAIVGLVKPIIQDVREQGDAGVLKYTHKFEKATSLTSPVLKAPFPAELMKLSPEVQEAIDVSISNIARFHSAQKGSNDALSMETMPGVVCSRFSRPIERVGCYIPGGTAVLPSTAMMLGVPAMVAGCKKIVFASPPRADGSITPEIVYVAHKVGAESIVLAGGAQAVAAMAYGTESVSKVDKILGPGNQFVTAAKMLVSNDTSAGVSIDMPAGPSEVLVIADKAANPAFVASDLLSQAEHGVDSQVILIAIDLNEQELKAIEDEVDRHARALPRMDIVRGSLAHSVTFVVRDLDEAMALSNDYAPEHLILQIQNAEAAVEKVQNAGSVFIGQWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLGSFLKHITSSNLTADGLLRLSKTVETLAAVEGLDAHKRAVSIRVAAMKQEQL
Protein: Ferric enterobactin transport ATP-binding protein FepC (EC 7.2.2.17) (P23878)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex FepBDGC involved in ferric enterobactin uptake. Responsible for energy coupling to the transport system (Probable).
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:3011753}; Peripheral membrane protein {ECO:0000269|PubMed:3011753}.
Interaction partners:
- Ferric enterobactin-binding periplasmic protein FepB
- Ferric enterobactin transport system permease protein FepD
- Ferric enterobactin transport system permease protein FepG
- Iron
- Ferrienterobactin receptor
- Fe
- Enterobactin exporter EntS
- Fe
- Iron
- Iron
Sequence:
MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS
Protein: Longipin (C0HJF8)
Organism: Acutisoma longipes (Neotropical harvestman) (Goniosoma longipes)
Function: Has antifungal activity against yeasts like C.albicans MDM8 (MIC=15-30 uM), C.albicans IOC 4558 (MIC=7.5-15 uM), C.tropicalis IOC 4560 (MIC=3.8-7.5 uM) and C.guilliermondii IOC 4557 (MIC=3.8-7.5 uM) but not against filamentous fungi like A.niger, C.herbarum ATCC26362 or P.farinosus IBC251. Has weak activity against the Gram-positive bacterium M.luteus A270 (MIC=60-120 uM) and against Gram-negative bacteria P.aeruginosa ATCC27853 (MIC=60-120 uM) and S.marcescens ATCC4112 (MIC=60-120 uM). Not active against S.aureus ATCC 29213 and S.epidermidis ATCC 12228, M.luteus BR2, E.coli D31, E.coli SBS363 or E.cloacae beta12. Probably acts by disrupting target cell membranes.
Subcellular location: Secreted {ECO:0000269|PubMed:27997568}. Target cell membrane {ECO:0000303|PubMed:27997568}.
Interaction partners:
Sequence:
SGYLPGKEYVYKYKGKVF
Protein: Sperm protein associated with the nucleus on the X chromosome D (Cancer/testis antigen 11.4) (CT11.4) (Nuclear-associated protein SPAN-Xd) (SPANX-D) (SPANX family member D) (Q9BXN6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with nuclear craters. {ECO:0000250}.
Interaction partners:
Sequence:
MDKQSSAGGVKRSVPCDSNEANEMMPETSSGYSDPQPAPKKLKTSESSTILVVRYRRNFKRTSPEELVNDHARKNRINPLQMEEEEFMEIMVEIPAK
Protein: Zinc finger protein 547 (Q8IVP9)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MAEMNPAQGHVVFEDVAIYFSQEEWGHLDEAQRLLYRDVMLENLALLSSLGCCHGAEDEEAPLEPGVSVGVSQVMAPKPCLSTQNTQPCETCSSLLKDILRLAEHDGTHPEQGLYTCPAHLHQHQKEQIREKLSRGDGGRPTFVKNHRVHMAGKTFLCSECGKAFSHKHKLSDHQKIHTGERTYKCSKCGILFMERSTLNRHQRTHTGERPYECNECGKAFLCKSHLVRHQTIHSGERPYECSECGKLFMWSSTLITHQRVHTGKRPYGCSECGKFFKCNSNLFRHYRIHTGKRSYGCSECGKFFMERSTLSRHQRVHTGERPYECNECGKFFSLKSVLIQHQRVHTGERPYECSECGKAFLTKSHLICHQTVHTAAKQCSECGKFFRYNSTLLRHQKVHTG
Protein: Dehydrogenase/reductase 2 (H0YJP4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAGYSTRL
Protein: Argonaute protein wago-1 (Worm-specific argonaute protein 1) (Q21770)
Organism: Caenorhabditis elegans
Function: Argonaute protein which is involved in the endogenous small interfering RNA (endo-siRNA) pathway. Interacts with secondary 22G-RNAs, which are RNA-dependent RNA polymerase-derived endo-siRNAs, typically 22 nucleotides in length with a 5'guanosine residue. In the germline, functions in a genome surveillance system to silence transposons and aberrant transcripts.
Subcellular location: Cytoplasmic granule {ECO:0000269|PubMed:19800275, ECO:0000269|PubMed:24684931}.
Interaction partners:
- Guanyl-specific ribonuclease pgl-1
- ATP-dependent RNA helicase glh-1
- RNA-directed RNA polymerase
- DEAD-box ATP-dependent RNA helicase rde-12
- NFX1-type zinc finger-containing protein 1 homolog
- Guanyl-specific ribonuclease pgl-3
- MUTator
- Helicase ATP-binding domain-containing protein
- RNA-directed RNA polymerase
- Argonaute protein hrde-1
Sequence:
MSPHPPQPHPPMPPMPPVTAPPGAMTPMPPVPADAQKLHQSTGNDACIKRLQQLNVEDGAKMYMKPTEPGKMGRPVDIQTNVFGIEVTKETTVHRFMVHAKADLTSTKEVTFTKKGKEDFVVQDRRDKCCNIFFLAVEKNPEFFKMKDGNQIVYDGQSTLYTTVNLFSELDANGTKSKVFQINGADTGNDDLKTLPCISLEIYAPRDNSITLSSENLGKRTADQNIEVNNREYTQFLELALNQHCVRETNRFGCFEHGKVYFLNATEEGFDQRDCVDVGDGKQLYPGLKKTIQFIEGPYGRGQNNPSLVIDGMKAAFHKEQTVIQKLFDITGQDPSNGLNNMTREKAAAVIKGLDCYSTYTNRKRHLRIEGIFHESATKTRFELPDGKTCSIAEYYADKYKISLQYPNANLVVCKDRGNNNYFPAELMTVSRNQRVTIPQQTGNQSQKTTKECAVLPDVRQRMIITGKNAVNITLENELLVALGIKVYSEPLMVQARELDGKELVYQRSVMSDMGKWRAPPGWFVKPATVPDLWAAYAVGNPGCRFSIGDVNQLVGMFIDSCKKKGMVIKPPCETGLYSTEKIMTQLEKVAASKCKYVLMITDDAIVHLHKQYKALEQRTMMIVQDMKISKANAVVKDGKRLTLENIINKTNVKLGGLNYTVSDAKKSMTDEQLIIGVGVSAPPAGTKYMMDNKGHLNPQIIGFASNAVANHEFVGDFVLAPSGQDTMASIEDVLQNSIDLFEKNRKALPKRIIIYRSGASEGSHASILAYEIPLARAIIHGYSKEIKLIFIVVTKEHSYRFFRDQLRSGGKATEMNIPPGIVLDNAVTNPACKQFFLNGHTTLQGTAKTPLYTVLADDCKAPMDRLEELTFTLCHHHQIVSLSTSIPTPLYVANEYAKRGRDLWGELTTKGPIEAKESQGERLKELTKEIGYKQTDLNQKRVNA
Protein: Uncharacterized protein (B7WN88)
Organism: Caenorhabditis elegans
Interaction partners:
- Solute carrier family 23 member 2
- MARVEL domain-containing protein
- Serpentine Receptor, class H
- G-protein coupled receptors family 1 profile domain-containing protein
- Receptor L-domain domain-containing protein
- FAM192A_Fyv6_N domain-containing protein
- RUN domain-containing protein
Sequence:
MICWLNLSIFYFVFSLYQCHQEELSQNIEVTASDSAAEHEVFEGISSNIAGKGEKLEEEIDNIGIVMQPEPRVVHEASEVSDNIELNIKDDLNLKSRLDNFTRAKFRQSTTVTPNIVAVEPSIEGVEDDLDHDEQGEPEDSEIRNRNEHHFAELGGKMKERRDHVDDPDIQEPLNKPISAIPEETSNSATIQYERSSSGTQNPQTSLNIPTAQNVPKLKQLKNQEILKDHFISEVSDVSNVADVSAPIVISQVPEILNGEPAGVPANFEEEDKERVEEEEDRISWDLIHFLLLLSPYEEGEVTWWTIVLEAVKCSLRSCHNSSSHWHDRSVYLPRITRHRRQDSDYLPGALSPTTPKPCLCNNLETYFEKLYESVGKKKKEKKISNSTTKFV
Protein: Transcriptional adapter 1 (Transcriptional adapter 1-like protein) (Q5BJQ7)
Organism: Rattus norvegicus (Rat)
Function: Probably involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription factor SPT20 homolog
- SPT3 homolog, SAGA and STAGA complex component
- Transcriptional adapter 3
- Transcription initiation factor TFIID subunit 9B
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 10
- SAGA-associated factor 29
- Transcriptional adapter 2-alpha
- TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
- Transcriptional adapter
Sequence:
MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFPAPCASQNPASHPHTDDAEQQAAFLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC