wanglab/gogpt-training-data huggingface dataset:
Protein: ABC transporter C family member 2 (ABC transporter ABCC.2) (Q54VJ0)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
- ABC transporter G family member 1
- ABC transporter G family member 15
Sequence:
MIKNLKQKIKNRFSYSLLSEDDNTDYFSKPCPEDNATLWQRFTFGWTERMLMTGYFNGPLEMKDVSDLPDRNKVNITAPFLDTIDYNSKYPLIKQIYKEFVSRNKISVATKIFVAIVSILSPLCLKYFIYYIKLDESQKTFKFGFLLCVLLFLSSLSLTLSQQYGYWFGLQTSLHARGAITQKIFEKTLRLSNQAKRLYNSGTIMNIISVDVGTFSDFFWNNHIEIFVFPFQILALLILLCWIVGLSGLVGFGVMVVSIPLCTFLSTKIAKNLRISLGYADTRCNLTSEFINGIRFLKLYAWEQLFLDRIEEQRTLQLKYLYRRAIYWILDRMITQVTSALVLVATFSTYALTGNQMTLEVAFTAMTIFVNLRRPLEMLPEAIHRALSLIPSSKRIENFLQSPEIQDQPFLEQYSNNKLSIRNNNNNNNNVSSTSSIASSASSNELFDVKINNGTFDWNEIDDLDSGMIINDVRGFAISSDINDMDEMILGDEKVGKSNDTNNGIEYDGAVQPSSSSYVLNNINFIAPAGKLTVICGIVGSGKTSLVSGLIGEIYRVSGSVNIPNNISFTTQQPFLLSTSLRDNILFGKPMNMERYKKVIDACCLTPDLLQLAAKDLTEIGERGINLSGGQKQRISLARALYSDSDCFILDEPLSAVDPEVASHLFDHCIQGMMKDKTRILVTHQLQFIPSADHIIVVDNGVLTQGTYSELKEKGIDFESIMKTKKLNIDENDQSSTSTTDKKSSTSSSSSELKKSTSLLNSTKELDINTIISEKNDPNLIEKAKLLVKEDRNEGEVGFEVYRQYFRHGSLNLFFLTCALYFISQIIFQLSDFWLTIWTNDETNQHDDKYYILYYCIFIGAFIVFLVVRYFMMASITFAASKKLHSELLNSVAFASCQFFDTNPSGRILNRFSKDISDIDLILMENFSDVLQCGSTVVVALFMMIYITPLISIPFAILVVVYYVIQKLYRASSVELKRMESITRSPVFSLLAEAYNGLVTIRCYQQQKRFIEMMQNHININLRLFFYSFSVHRWVGIRLEFITALIVFFTAFSSLFSSNTGFSVLAVTTALGICSYLNWTIRQMTELEVKMNSVERVESYIKTPREGIRHTSEFEDEIDIDGEIEMDFTKWPSRGEVEFKNVEIKYRPTADPSLKNISFKINAKDHIGVVGRTGAGKSTVGISLFRMVECSKGSIFIDGVDISKVGLHELRDALGIVPQDPFIFSGSIRMNIDPFNKYTDDEIWTALEKVKLKDAISSMPLKLESGVQENGDGLSFGQKQLLCLSRTILKNSKVVLMDEATSGIDYVTAALLKQTIDENFNDCTMLTIAHRLDTIIDSTKIAVIDKGELVEYDTPMNLIKTEGSRFKKLVKYQTDFYEESQKKF
Protein: Daam1l protein (Disheveled-associated activator of morphogenesis 1b isoform X2) (Dishevelled-associated activator of morphogenesis 1b) (B3DJI0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAPRKRGGGGHGASFFFCCFQSSDHPEITYRLREDFALQTMEPALPIPSYDELDAMFSELVDELDLTEKHREAMFALPAEKKWQIYCSKKKEQEENKGATSWPEFYIDQLNSMAARKTLLALEKEEEEERNKTIESLKTALRTQPMRFVTRFIDLDGLTCILNFLKSMDYETTESQIHTSLIGCIKALMNNSQGRAHVLSHTESINIIAQSLATDNIKTKVAVLEIMGAVCLVPGGHKKILEAMLHYQKFACERTRFQTLLNDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGESSLEFRVHLRYEFLMLGIQPIIDKLRSHENSTLDRHLDYFEMLRNDDELTLSRRFEAIHIDTKSATQVFELVRKKLAHTDAYPHFMSVLHHCLLMPHKRSGNTVQYWLLLDRIVQQMVLQNDKGHDPDATPLENFNVKNVVRMLVNENEVKQWKEQAEKMRKDHHELQQKMEKKERECDAKTQEKEEMMQTLNKMKEKLEREMGEHKLVKQQVAEMTTRLHELSTRQIASVPGGPPVSGPLGGPLLPPPPPPPPGGMMPPPPPPPPCGAMMPPPPPPPPGGPPPPPGRPPFGSAPPPPGAPIGPSLKKKNIPQPSNPLKSFNWAKLSENKLEGTVWADVDDGRVFKILDLEDIEKTFSAYQRQQKETEDDTLSSKKVKELSVIDGRRAQNCNILLSRLKLSNEEIKRAILTMDEQEDLPKDMLEQMLKFVPEKSDVDLLEEHKHELDRMAKADRFLYEMSRINHYQQRLQSLYFKKKFAERIAEIKPKVEALTKASKEVLHSRNFKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITILEKKYSKVMLFQEELKNVPEAAKVNMTELEKEINNLRSGLKSVESELDFQKKRPQEYGDKFVSVVSQFITVASFSFSDVEDSLCEAKELFIKTVKHFGEDADKMQPDEFFGIFDQFLQSFAEARQENENIRRRKEEEERRARMEAQLKEQREKERKARKAKENGEDDGGEFDDLVSALRSGEVFDKDLSKMKRNRKRINSQTSDSGRERPITKLNF
Protein: Probable inactive lysine-specific demethylase JMJ19 (Jumonji domain-containing protein 19) (AtJMJ19) (Protein JUMONJI 19) (Q8L7T6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- ATP synthase subunit b, chloroplastic
- ATP synthase subunit d, mitochondrial
- ATPase, F1 complex, OSCP/delta subunit protein
- ATP synthase subunit O, mitochondrial
- ATP synthase subunit delta, chloroplastic
- Polycomb group protein FERTILIZATION-INDEPENDENT ENDOSPERM
- ATP synthase subunit a, chloroplastic
- ATP synthase subunit a.
- ATP synthase subunit a-2
- ATP synthase subunit a-1
Sequence:
MGIEGVSTYLKSGNMDTISAPPGFVSQTSFVLRNVPRDKESPRSVSRQEQTTGFGTDDKDSCNMFLKSRPWIVHGHTIPSSEALRPKKTEVRRRRPLKVSETKVLEEAPVFNPTEEEFRDTLSYISSLRDRAEPYGICCVVPPPSWKPPCLLKEKQIWEASTFFPQVQLFGIQTENRKIKKEVDADSNDAASEGVQLCRVERGPGYTLKSFKNFADTYKKSHFGMKDEVLGSENSSPSLKPNELIVADIEKEYRQIVESPLIEIGVLYGNDLDTATFGSGFPLSAPSESSKYSSGWNLNSTAKLPGSLLSLEDCESVCVPRLSVGMCLSSQFWKSEKERLYSLCYLHVGAPRVWYSVAGCHRSKFKAAMKSFILEMSGEQPKKSHNPVMMMSPYQLSVEGIPVTRCVQHPGQYVIIFPGSYYSAFDCGFNCLEKANFAPLDWLPHGDIAVQVNQEMSKTSLISYDKLLFSAAREAVKCLKEYGLSKKNTACYTRWNDSCGTDGLFSNIIKSRIKLEKNRREFLISSLESQRMDKSYDAVNKRECCVCLGDLYLSAVNCSCSANRYSCLNHMRKLCACPCDRKSFLYRYTMDELNLLVEALEGKKLSSMFRWAGIDQKFCASPATTSSKPEEDKGKETDEVTPCNITRKDVAAGTKDQTRVKARSLADILNVKDGNNDAKETLESCSKKSNRPCDNDSSEANAPKKQKQ
Protein: 3-aminobutyryl-CoA aminotransferase (EC 2.6.1.111) (HemL-like protein) (B0VH76)
Organism: Cloacimonas acidaminovorans (strain Evry)
Function: 3-aminobutyryl-CoA aminotransferase that acts specifically on coenzyme A (CoA) esters and catalyzes the conversion of 3-aminobutyryl-CoA into acetoacetyl-CoA in an alternative pathway of lysine fermentation.
Interaction partners:
- CTP synthase
Sequence:
MAEKLKLARSMSLFEEAKQLVPGGVAGIRRPYNFVPGEYPIFFDHGKGGRVVDVDGNEYIDFLCAYGPIIIGYREDEIDDAVINQIKNKGFCFSLTQEMQNTLVKKLRELIPCCEMAALVKTGSDATTIAIRVARGYTGKTKIARYGYHGWHDWCVEVKGGIPPKLYEDIYEFHYNDLDSLKAILEANKDDMAGIIITPIGHPNGAEVQMPKPGYLEAVRELANQYHCLLIFDEIRSGFRCSLGGAQKLFGVTPDLSTFGKAMANGYAIAALVGKEEYMQVLADKVFLSSTFFPNSDGIVAAIKTIEILERDRILDVVAAKGRKFGAEVEKVVEESGVPVNFTGAPWMPYITFKKDEAGLYKKLRTEYYTQLIRHNVFMQPYHHGYICYRHTDEDLAYTVEAIRESLAEVKKML
Protein: G protein subunit beta 5 (GNB5 protein) (Q96F32)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATEGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKVRHCSQPRYRGFRIPAYLKVLWSSCPALS
Protein: Developmental and secondary metabolism regulator veA (Velvet complex subunit A) (Q2UNT7)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity). The velvet complex hat acts as a global regulator for secondary metabolite gene expression. Controls the expression of the penicillin gene cluster.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:C8VTV4}. Cytoplasm {ECO:0000250|UniProtKB:C8VTV4}. Note=Enriched in the nucleus in the dark (By similarity). {ECO:0000250|UniProtKB:C8VTV4}.
Interaction partners:
- Secondary metabolism regulator laeA
- C2H2 type master regulator of conidiophore development brlA
- Velvet domain-containing protein
- Conidiophore development regulator abaA
- Developmental regulatory protein wetA
- pH-response transcription factor pacC/RIM101
- DNA-binding protein creA
- Orotidine 5'-phosphate decarboxylase
- Trehalase
Sequence:
MATRAPLAPPPNETEASVSRITREGKKLTYKLNVMQQPERARACGAGAKSSADRRPVDPPPVVELRVYESDPNDDLNKTDITFAYNANFFLYATLETARPMAQGRFAPNPTCPVLTGVPVAGVAYLDRPSQAGYFIFPDLSVRHEGVYRLNFHLYEETKESKDANENAPIQSLSNPMPSKPMAPKSFLEFRLEVVSVPFTVFSAKKFPGLATSTSLSRVIAEQGCRVRIRRDVRMRRRGEKRTDDYDYDEERVYRSSDRISTPDTHGYAGTPVERPRSTSTSTVDPSFPYGVDAQRRSSGATEYGFQGAQPYQRPLPPAPGPAPAAVSTPAPPAPPAPPSHNPGYQSHLSFGSTQTQYPAPQLPPTPQTASTLAAPYSPHPSYSHARNPSTSAEYETPGYSYPPSRMSTERSSYPKNGLPPLRLEPPKPLNMPSGEPRSSDPNAYHSVAQSAAPRSQTPSSSLVPSLPPLKALSGDYPNNLSQSSSSTSQSPSHDLGAGKKFFWDTGASLSKRSYEDSFGHDDRPLYNGMRPDTESYPRRLSDASRNFYNETRDEMAYKRANGRMATKISPALQ
Protein: Hepatic and glial cell adhesion molecule (glialCAM) (Hepatocyte cell adhesion molecule) (Protein hepaCAM) (Q14CZ8)
Organism: Homo sapiens (Human)
Function: Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256}. Cell membrane {ECO:0000269|PubMed:22405205}; Single-pass type I membrane protein; Cytoplasmic side {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256}. Note=Colocalizes with CLCN2 at astrocyte end-foot in contact with brain capillaries and other glial cells (By similarity). In MCF-7 breast carcinoma and hepatic Hep 3B2.1-7 and Hep-G2 cell lines, localization of HEPACAM is cell density-dependent. In well spread cells, localized to punctate structures in the perinuclear membrane, cytoplasm, and at cell surface of protusions. In confluent cells, localized predominantly to the cytoplasmic membrane, particularly in areas of cell-cell contacts. Colocalizes with CDH1. {ECO:0000250|UniProtKB:Q640R3}.
Interaction partners:
- ATP-sensitive inward rectifier potassium channel 10
Sequence:
MKRERGALSRASRALRLAPFVYLLLIQTDPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDRPVVKWQLKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKPSYTWLKDGKPLLNDSRMLLSPDQKVLTITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCACWKPSKRKQKKLEKQNSLEYMDQNDDRLKPEADTLPRSGEQERKNPMALYILKDKDSPETEENPAPEPRSATEPGPPGYSVSPAVPGRSPGLPIRSARRYPRSPARSPATGRTHSSPPRAPSSPGRSRSASRTLRTAGVHIIREQDEAGPVEISA
Protein: 14-3-3 protein zeta (14-3-3-like protein) (Protein Leonardo) (P29310)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required in Raf-dependent cell proliferation and photoreceptor differentiation during eye development. Acts upstream of Raf and downstream of Ras, and is essential for viability. Acts as a negative regulator of the slo calcium channel via its interaction with slo-binding protein slob. Inhibits yki activity by restricting its nuclear localization. Binds to and promotes the activity of phosphoinositide 3-kinase Pi3K68D which converts phosphatidylinositol to phosphatidylinositol-3-phosphate and promotes maturation of early endosomes.
Subcellular location: Cytoplasm {ECO:0000250}. Early endosome {ECO:0000269|PubMed:27015288}.
Interaction partners:
- Raf homolog serine/threonine-protein kinase Raf
- AT08303p
- 14-3-3 protein epsilon
- Forkhead box protein O
- Transcriptional coactivator yorkie
- Gigas, isoform A
- LD23779p
- non-specific serine/threonine protein kinase
- Rap GTPase activating protein 1, isoform H
- P-element somatic inhibitor, isoform C
Sequence:
MSTVDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN
Protein: Myosin heavy chain 2 (A0A0G2K484)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, myofibril {ECO:0000256|ARBA:ARBA00004657}.
Interaction partners:
Sequence:
MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESFVKATVQSREGGKVTAKTEGGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEAPSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSGGQAAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFRKMMERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE
Protein: Actin-related protein 2/3 complex subunit 4 (Q9VMH2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR039100}.
Interaction partners:
- Actin-related protein 2/3 complex subunit 2
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 5
- Actin-related protein 3
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit
- Actin-related protein 2
- LD35927p
- Structure-specific endonuclease subunit SLX1 homolog
- RE12101p
Sequence:
MAATLKPYLTAVRHSLTAAMCLQDFPSQVVERHNKPEVEICSSKELVLTPVVVSRNEREKVLIEPSINSVRVSIAVKQADEIERILCHKFTRFMMRRAESFVILRRKPIEGYDISFLITNFHTEQMYKHKLVDFVISFMEEIDKEISEMKLAVNARARTCAEEFLKRF
Protein: Cyclin-dependent protein kinase inhibitor SIM (Protein SIAMESE) (Q9LZ78)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle. Inhibits the kinase activity of CYCD3-1/CDKA-1, CYCD2-1/CDKA-1 and CYCB1-1/CDKB1-1 complexes in a dose dependent manner. Cooperates with SMR1 and SMR2 to promote endoreplication during leaf development. Required for normal trichome endoreplicating cell cycles. Positive regulator of effector-triggered immunity (ETI).
Subcellular location: Nucleus {ECO:0000269|PubMed:17098811}.
Interaction partners:
- Cyclin-dependent kinase inhibitor 1
- GDSL esterase/lipase At5g45910
- Probable F-box protein At2g36090
- CASP-like protein 1E1
- SREBP regulating gene protein
- Peptidyl-prolyl cis-trans isomerase FKBP43
- Transcriptional regulator TAC1
- WAT1-related protein At1g25270
- Cyclin-U2-2
Sequence:
MDLDLIQDLPILNFPPAIKIRANTNRDDDGGGCTTPTSSDHKIPPTTATTPPPPPQKPRPPSTPSSLGIRSCKRKLMTSLSKYEIIVNKDEIERFFSSVYNQTMASSTTTAITVAKRRRSFRSCSRR
Protein: BNIP3, isoform C (BNIP3, isoform D) (BNIP3, isoform E) (RE54374p) (Q8IPU7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
MAGIKSPDRITPLPFNNGEEYLRLLREAQRESNQSSRVVSLASSRRDTPRDSPKSPPNSPQSELCPDDELRNVYINYWTKGGDKQNAGNEDWLKNWNQPPSSWNIEDSSRDAGDEGEKKKTNTGYSIRLKRLGSNSLFSREILYSLLVTNVLSLLLGAGFGLWLSKRGILLTRVVID
Protein: Integrator complex subunit 11 (A0A087WYI0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPEIRVTPLGACPVLSWNLVLPPGRGSRAPSSTDTRTGFHVLPHGVNDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLKQKIEQELRVNCYMPANGETVTLPTSPSIPVGISLGLLKREMAQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLHDTRKEQETALRVYSHLKSVLKDHCVQHLPDGSVTVESVLLQAAAPSEDPGTKVLLVSWTYQDEELGSFLTSLLKKGLPQAPS
Protein: C2H2-type domain-containing protein (Q3V1H6)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYITCLCSMLPSEEAIQEIAKVDCKGVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDDGKEDKQYRRSLSDQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKELFVPHLMEHVKMPPSRSHRSRKKLLLKSAQRGIYPKSPTGSLEQNPEQARGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVLGCKKFYYSKIEYQNHLSMHNVESPDGELKKSVKLEEPGAGGKQDCVDQSHLLDETEKSHSLEDHHLCPGSASAHIDTTETLKDNSDSNSSDQLSHSSSTSITEELIDTLDHSETMQDLLLSHEKVFVPSSLKDKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKP
Protein: Myoferlin (Fer-1-like protein 3) (Q9NZM1)
Organism: Homo sapiens (Human)
Function: Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity).
Subcellular location: Cell membrane; Single-pass type II membrane protein. Nucleus membrane; Single-pass type II membrane protein. Cytoplasmic vesicle membrane; Single-pass type II membrane protein. Note=Concentrated at the membrane sites of both myoblast-myoblast and myoblast-myotube fusions. Detected at the plasmalemma in endothelial cells lining intact blood vessels (By similarity). Found at nuclear and plasma membranes. Enriched in undifferentiated myoblasts near the plasma membrane in puncate structures. {ECO:0000250}.
Interaction partners:
- Neuroblast differentiation-associated protein AHNAK
- EH domain-containing protein 2
- Calpain-3
- EH domain-containing protein 3
Sequence:
MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLDFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDLVIGYDPPSAPHPNDLSGPSVPGMGGDGEEDEGDEDRLDNAVRGPGPKGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQALMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGKDGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKSDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKPNV
Protein: Tubulin alpha-3 chain (EC 3.6.5.-) (Mechanosensory abnormality protein 12) (MEC-12) [Cleaved into: Detyrosinated tubulin alpha-3 chain] (P91910)
Organism: Caenorhabditis elegans
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Component of the large-diameter neuronal microtubules which contains 15 protofilaments. Plays a role in mechanosensory transduction (touch sensitivity).
Interaction partners:
- Tubulin beta-1 chain
- Alpha-tubulin N-acetyltransferase 1
- Tubulin beta-4 chain
- Tubulin beta-2 chain
- Tubulin beta chain
- Tubulin beta chain
- MEC-5
- Mechanosensory protein 2
- Kunitz/Bovine pancreatic trypsin inhibitor domain protein
- Alpha-tubulin N-acetyltransferase 2
Sequence:
MREVISIHIGQAGVQIGNACWELYCLEHGIQPDGQMPSDKSLGGSDDSFSTFFSETGSGRHVPRAVMVDLEPTVIDEIRTGTYRSLFHPEQLITGKEDAANNYARGHYTIGKEIIDLTLDRIRRLADNCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKAKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCSFMVDNEAIYDICRRNLDIERPSYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATFSPVISAEKAYHEQLSVAEITNMCFEPHNQMVKCDPRHGKYMAVCLLFRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVPRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSMEDNGEEGDEY
Protein: Peroxisomal membrane protein 11A (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Peroxisomal coatomer receptor) (Peroxisomal membrane protein 26) (Pmp26p) (Protein PEX11 homolog alpha) (PEX11-alpha) (RnPEX11p) (O70597)
Organism: Rattus norvegicus (Rat)
Function: May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:9548716}; Multi-pass membrane protein {ECO:0000269|PubMed:9548716}.
Interaction partners:
- Peroxisomal biogenesis factor 11 gamma
- Peroxisomal biogenesis factor 19
- Peroxisomal membrane protein PEX13
- Peroxisome biogenesis factor 10
- Peroxisomal biogenesis factor 11 beta
- Peroxisomal membrane protein PEX14
- Peroxisomal biogenesis factor 3
- Peroxisomal membrane protein PEX16
- Peroxisome assembly protein 12
- Peroxisomal ATPase PEX6
Sequence:
MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVLHAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGINREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSSGDPPKYSVANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKLKAR
Protein: UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (A0A8I6G7V9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
ERVVQVLIYIAMSQDGASQFQEVILQELELSVKKELEKILTTATSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNPKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH
Protein: L-Ala-D/L-Glu epimerase (AE epimerase) (AEE) (EC 5.1.1.20) (Q8A861)
Organism: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
Function: Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and may play a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the epimerization of L-Ala-D-Asp, L-Ala-L-Glu, L-Ala-L-Ser, L-Ala-L-Pro, L-Ala-L-L-Val, L-Ala-L-Thr, L-Ala-L-Leu, L-Ala-L-Ile and L-Gly-L-Glu (in vitro).
Interaction partners:
- Dipeptidyl-peptidase VI
Sequence:
MPNRRDFLKTAAFATLGSGIAVSQVLAGECMPSAIHINKYGIGGKMKMTFFPYELKLRHVFTVATYSRTTTPDVQVEIEYEGVTGYGEASMPPYLGETVESVMNFLKKVNLEQFSDPFQLEDILSYVDSLSPKDTAAKAAVDIALHDLVGKLLGAPWYKIWGLNKEKTPSTTFTIGIDTPDVVRAKTKECAGLFNILKVKLGRDNDKEMIETIRSVTDLPIAVDANQGWKDRQYALDMIHWLKEKGIVMIEQPMPKEQLDDIAWVTQQSPLPVFADESLQRLGDVAALKGAFTGINIKLMKCTGMREAWKMVTLAHALGMRVMVGCMTETSCAISAASQFSPAVDFADLDGNLLISNDRFKGVEVVNGKITLNDLPGIGVMKI
Protein: Uncharacterized protein C1711.15c (Q9P776)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Uncharacterized GPI-anchored protein SPAC750.07c
Sequence:
MKKRFDWCLILIDIIEKLLNEADLSILIIVIC