wanglab/gogpt-training-data huggingface dataset:
Protein: Transmembrane protein 9 (B1ALM4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MKLLSLVAVVGCLLVPPAEANKVREVSLQHLVTTTVHGHPVYRADSESSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLIRKPDAYTEQLHNEEENEDARSM
Protein: 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H) (Q8QZS1)
Organism: Mus musculus (Mouse)
Function: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- 3-hydroxyisobutyrate dehydrogenase, mitochondrial
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein mS35
- Enoyl-CoA hydratase, mitochondrial
- Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS10m
Sequence:
MGQPYAWRLLSRVSSFRRASVILQHLRMSMHTEAAEVLLERRGCGGVITLNRPKFLNALSLNMIRQIYPQLKTWEQDPDTFLIIIKGAGGKAFCAGGDIKALSEAKKARQNLTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYFLALTGYRLKGRDVHRAGIATHFVDSEKLRVLEEELLALKSPSAEDVAGVLESYHAKSKMDQDKSIIFEEHMDKINSCFSANTVEQIIENLRQDGSPFAIEQMKVINKMSPTSLKITLRQLMEGSSKTLQEVLIMEYRITQACMEGHDFHEGVRAVLIDKDQTPKWKPANLKDVTDEDLNSYFKSLGSSDLKF
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit (Q5AJG7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU363103}; Peripheral membrane protein {ECO:0000256|RuleBase:RU363103}; Matrix side {ECO:0000256|RuleBase:RU363103}.
Interaction partners:
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit MCI4
- NAD-dependent epimerase/dehydratase domain-containing protein
- Fesur1p
- NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- Cytochrome b-c1 complex subunit 7, mitochondrial
- Nuc2p
- Complex 1 LYR protein domain-containing protein
- Uncharacterized protein
Sequence:
MSTSIFRTLKNIYSSGLKRAAWQIHHHNDTKRGWLVGIDDFGNKYYETDAPEEIHLRTRWVEYSQWNQDMSQVEPGWHYWLGYGTNTPPNALIGDAKTTRAYPLPAHHKPNLTNTPGAYVCYNTAKPKFKSWTPEVKERA
Protein: Heat shock factor protein 5 (HSF 5) (Heat shock transcription factor 5) (HSTF 5) (Q4G112)
Organism: Homo sapiens (Human)
Function: May act as a transcriptional factor.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q5ND04}. Chromosome {ECO:0000250|UniProtKB:Q5ND04}. Note=Expressed primarily in the XY body of pachytene spermatocytes. {ECO:0000250|UniProtKB:Q5ND04}.
Interaction partners:
Sequence:
MEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGEGLLIDQPLFEAELLSPPGPGGGGGTAGAGAEPELFKTTSFTSFIRQLNLYGFRKVVLGGPGGGKPAGNGPLHHFHNPHFRRDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNRFQRLLITSASAATAPLQHQQPPPPAGPRPEPHGPVAVGQFHRSFRRDSLSPYSCVSTPSHDHSTYPLKGLDRTPVPHRIWQNSLGMHPGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSTTSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSPTHMDALSSCVTPTASSYAHCNYFQNPSMQSSYPVEFLPSNWPCSTTDENTKTEVNLEAVFQIVDELHSSPKLEMVKVEPVENQCPTSPSYRGQHILANSNNSNPCSASQASQLEPLTPVGSDIMSFVVGTEQAVACSLPQSPEYIYTIHTAQPVENSTIQESAAIQQAHVKLKEHLNHNPSPSSVVFVQEGPPFSTHQVDANIKCQTSSRENILPSEQMGFLISEMGPASKPSEDTGLATPARYREHRSNSQQGKSPDLHLLVDVACKQERFPKEEELKE
Protein: Prohibitin-2 (O94550)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P50085}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P50085}; Intermembrane side {ECO:0000250|UniProtKB:P50085}.
Interaction partners:
- Prohibitin-1
- ATP-dependent zinc metalloprotease YME1 homolog
- Elongation factor Tu
- Probable mitochondrial-processing peptidase subunit beta
- Mitochondrial inner membrane m-AAA protease component yta12
- RQC trigger complex subunit RQT4 homolog
- Uncharacterized protein C16G5.07c
- Mitochondrial Rho GTPase 1
- Mitochondrial import inner membrane translocase subunit tim13
- Non-selective voltage-gated ion channel
Sequence:
MNRQRPFQQMNDLMKRGLPKGKYAFTGTGLLLALGLAGFAVQTSLFNVDGGHRAIKYSRIGGIKNLIYPEGTHFLIPWIETAIDYDVRAKPRNISSLTGTKDLQMVNINCRVLSRPDVHALPKIYRTLGGDYDERVLPSIVNEVLKSVVAQFNASQLITQRERVSRLVRENLMKRAARFNILLDDVSLTHVQFSPEFTAAVEAKQIAQQDAQRATFYVDRARMEKQGFIVRAQGEGRAAQLIGEAIKNKPGFIELRKLETAREIANILSKSNNKVMLNASTLLLDDIK
Protein: Transcriptional regulatory protein KdpE (P9WGN1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon. Upon phosphorylation by KdpD, functions as a transcription regulator by direct binding to promoter regions of target genes to positively regulate their expression.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Sensor protein KdpD
- Sensor-type histidine kinase PrrB
- Potassium-transporting ATPase potassium-binding subunit
- Sensor histidine kinase TrcS
- Transcriptional regulatory protein TrcR
- Potassium-transporting ATPase KdpC subunit
- Potassium-transporting ATPase ATP-binding subunit
- Probable transcriptional regulatory protein
- Sensor histidine kinase component HK1
- Transcriptional regulatory protein EmbR
Sequence:
MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
Protein: Bromodomain-containing protein 1 (O74350)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- NuA4 acetyltransferase complex subunit Tra2
- Histone acetyltransferase mst1
- Protein AF-9 homolog
- Chromatin modification-related protein eaf3
- Chromatin modification-related protein png2
- SWR1-complex protein 4
- Actin-related protein 4
- Chromatin modification-related protein vid21
- Chromatin modification-related protein png1
- Probable chromatin modification-related protein eaf7
Sequence:
MNIAQEVAVLQYLDIQQENPNAPNEELFNRTAESSLLLEPIEQDQLKDLVEEWMHDSNKSDSKLLSNQVSQNDNDARKNLRKRLRNDVLKDLAEEIQGCEKKLESLYEEVAKAKAKAVEDQLALEEADKEAKKAKTEAPVEAANKSLRSRKKTPEIAAPANIEPEVAPTTKTPKKRAALSNEEKQSLKKFQSAMLPMLDNISNHRFGAPFSHPVNRKEAPDYDSLVYKPQDLRTLKNMIKEGNITEVDELYREVLRIFANCKMYNGSDPANAMSIWGDECFRYTEELFDIYRQASTRSQ
Protein: Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) (Q586Z6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Triosephosphate isomerase
- Phosphoglycerate kinase
- Phosphoglycerate kinase
- Phosphoglycerate kinase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Phosphoglycerate kinase
- Transaldolase
- Transketolase
- Glucose-6-phosphate 1-dehydrogenase
Sequence:
MSVALFFSSFLAVPYFPCICLSFCGAEFIRANQTSKRLTTNLNMTIKVGINGFGRIGRMVFQALCDDGLLGNEIDVVAVVDMNTDARYFAYQMKYDSVHGKFKHSVSTTKSKPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTVKSAAEGHLRGGARKVVISAPASGGAKTFVMGVNHNDYNPREHHVVSNASCTTNCLAPLVHVLVKEGFGISTGLMTTVHSYTATQKTVDGVSVKDWRGGRAAALNIIPSTTGAAKAVGMVIPSTQGKLTGMAFRVPTADVSVVDLTFIATRDTSIKEIDAALKRASKTYMKNILGYTDEELVSADFISDSRSSIYDSKATLQNNLPNERRFFKIVSWYDNEWGYSHRVVDLVRHMAARDRAAKL
Protein: Abhydrolase domain-containing protein C22H12.03 (EC 3.1.-.-) (O94437)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Cardiolipin synthase
- Tryptophan--tRNA ligase, mitochondrial
- Multifunctional tryptophan biosynthesis protein
- Putative acyl carrier protein, mitochondrial
Sequence:
MSLKPVKLAFEKYSATVAKHPPVLIFHGLLGSKRNWRSLAKKFSCKLDRDIYAIDQRCHGDSPCVAPLSYSAMALDAFQFMKDHKLDKASIIGHSMGAKTAMVTALKWPDKVEKLVVVDNSPWYQDLPRDYGAYFRKMIQIDEANITKYSEADKMMSTVEKDILVRSFLLSNLKKDSNNSNTFKFRVPIELISKSLKTIEGFPASLNDLVYDSPTLVIRALKAPFIPDSALPVFKKFFPKYELVSLDCGHWVHFEKPKEFSESIINFLNN
Protein: Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon) (L7RTI5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR000551}. Cytoplasm, cytoskeleton {ECO:0000256|PIRNR:PIRNR000551}. Cell membrane {ECO:0000256|PIRNR:PIRNR000551}. Cytoplasm, perinuclear region {ECO:0000256|PIRNR:PIRNR000551}. Nucleus {ECO:0000256|PIRNR:PIRNR000551}. Note=Translocated to plasma membrane in epithelial cells stimulated by HGF. Associated with the Golgi at the perinuclear site in pre-passage fibroblasts. In passaging cells, translocated to the cell periphery. Translocated to the nucleus in PMA-treated cells. {ECO:0000256|PIRNR:PIRNR000551}.
Interaction partners:
Sequence:
MVVFNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIALNVDDSRIGQTATKQKTNSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQFEELLQNGSRHFEDWIDLEPEGRVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQGAVRRRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEEDRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP
Protein: Guanylate kinase (EC 2.7.4.8) (GMP kinase) (P46195)
Organism: Bos taurus (Bovine)
Function: Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP). Involved in the cGMP metabolism in photoreceptors.
Subcellular location: Photoreceptor inner segment {ECO:0000250|UniProtKB:Q64520}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q64520}. Note=Colocalizes with RD3 in photoreceptor inner segments and to a lesser extent in the outer plexiform layer. {ECO:0000250|UniProtKB:Q64520}.
Interaction partners:
- GMP synthase
- Adenine phosphoribosyltransferase
- Nucleoside diphosphate kinase
- Nucleoside diphosphate kinase A 2
- Cilia- and flagella-associated protein 206
- Ribonucleoside-diphosphate reductase
- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
- Inosine triphosphate pyrophosphatase
- Nucleoside diphosphate kinase, mitochondrial
- Nucleoside diphosphate kinase homolog 7
Sequence:
MSGPRPVVLSGPSGAGKSTLLKKLLQEHGSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLRPIYIFVQPPSLDVLEQRLRQRNTETEESLAKRLAAARADMESSKEPGLFDLIIVNDSLDKAYWALKEALSEEIKKAQGTGQS
Protein: Multiple organellar RNA editing factor 3, mitochondrial (RNA editing-interacting protein 3) (Q84JZ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in organellar RNA editing. Required for the processing of RNA editing sites in mitochondria.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25583991}.
Interaction partners:
- Pentatricopeptide repeat-containing protein At3g02330, mitochondrial
- AT4g30010/F6G3_40
- Pentatricopeptide repeat-containing protein At5g13270
- Pentatricopeptide repeat-containing protein At2g45350, chloroplastic
- Protoporphyrinogen oxidase 1, chloroplastic
- Pentatricopeptide repeat-containing protein At4g14050, mitochondrial
Sequence:
MALISTRRTLSTLLNKTLSSSTSYSSSFPTLSSRSRFAMPLIEKVSSSRTSLGPCYISTRPKTSGSGYSPLNDPSPNWSNRPPKETILLDGCDYEHWLIVMEFTDPKPTEEEMINSYVKTLTSVLGCEEEAKKKIYSVCTSTYTGFGALISEELSCKVKALPGVLWVLPDSYLDVPNKDYGGDLYVEGKVIPRPQYRFTEQRHTRPRPRPRYDRRRETMQVERREPSMGLHSPVNPGEFNKPSA
Protein: ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (EC 3.6.-.-) (ATP-dependent metalloprotease FtsH1) (YME1-like protein 1) (O88967)
Organism: Mus musculus (Mouse)
Function: ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (By similarity). Plays an important role in regulating mitochondrial morphology and function by cleaving OPA1 at position S2, giving rise to a form of OPA1 that promotes maintenance of normal mitochondrial structure. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins (By similarity). Required for normal, constitutive degradation of PRELID1. Catalyzes the degradation of OMA1 in response to membrane depolarization. Required to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1) (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q96TA2}. Mitochondrion {ECO:0000250|UniProtKB:Q96TA2}.
Interaction partners:
- Complex I assembly factor TIMMDC1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- ATP-dependent clpX-like chaperone, mitochondrial
- Metalloendopeptidase OMA1, mitochondrial
- ATP-dependent Clp protease proteolytic subunit, mitochondrial
- Presenilin-associated rhomboid-like protein, mitochondrial
- Lon protease homolog, mitochondrial
- Stomatin-like protein 2, mitochondrial
- YjeF N-terminal domain-containing protein 3
- Prohibitin-2
Sequence:
MFSLSSTVQPQVTIPLSHLINAFHSPKNISVSVNTPVSQKQHRDTVPEHEAPSSEPVLNLRDLGLSELKIGQIDKMVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLRSICSDLQYFPVFIQSRGFKTLKSRTRRLQSTSERLVEAQNIAPSFVKGFLLRDRGTDLESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR
Protein: C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) [Cleaved into: CXCL10(1-73)] (P02778)
Organism: Homo sapiens (Human)
Function: Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects. Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization. In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation. Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site. This recruitment is an essential element for neuronal reorganization (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:21183794}.
Interaction partners:
- C-C motif chemokine 5
- C-C motif chemokine 8
- C-C motif chemokine 21
- Eotaxin
- Stromal cell-derived factor 1
- C-C chemokine receptor type 5
- C-C motif chemokine 13
- Platelet basic protein
- C-X-C chemokine receptor type 3
- Platelet factor 4
Sequence:
MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
Protein: DNA-binding and peroxide stress resistance protein YaaA (UPF0246 protein YaaA) (P0A8I3)
Organism: Escherichia coli (strain K12)
Function: Involved in the cellular response to hydrogen peroxide (H(2)O(2)) stress. During H(2)O(2) stress, prevents oxidative damage to both DNA and proteins by diminishing the amount of unincorporated iron within the cell.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Uncharacterized transporter YaaJ
- Cyanate transport protein CynX
Sequence:
MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPPQISTLMRISDKLAGINAARFHDWQPDFTPANARQAILAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALAAQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFFDEDSSSNGELVFKRYEQR
Protein: Equilibrative nucleoside transporter 2 (mENT2) (36 kDa hydrophobic nucleolar protein) (36 kDa nucleolar protein HNP36) (Delayed-early response protein 12) (Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter) (Equilibrative NBMPR-insensitive nucleoside transporter) (Nucleoside transporter, ei-type) (Solute carrier family 29 member 2) (Q61672)
Organism: Mus musculus (Mouse)
Function: Mediates equilibrative transport of purine and pyrimidine nucleosides, and the purine base hypoxanthine.
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:Q14542}; Multi-pass membrane protein {ECO:0000305}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q14542}; Multi-pass membrane protein {ECO:0000305}. Nucleus membrane {ECO:0000250|UniProtKB:Q14542}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Equilibrative nucleoside transporter 3
- Equilibrative nucleoside transporter 1
- Sodium/nucleoside cotransporter 1
- Sodium/nucleoside cotransporter 2
- Solute carrier family 28 member 3
- Adenosine kinase
Sequence:
MARGNAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQGRLAGTNSSAETMGTNHTSPTDTFNFNNWVTLLSQLPLLLFTLLNSFLYQCIPESVRILGSLLAILLLFALTAALVKVDLSPGLFFSVTMASVWFINSFCAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLMSLASGVDAQTSALGYFITPCVGILLSIVCYLSLPHLKFARYYLTEKLSQAPTQELETKAELLQADEKNGVPISPQQASPTLDLDPEKEPEPEEPQKPGKPSVFVVFRKIWLTALCLVLVFTVTLSVFPAITAMVTTSSNSPGKWGLFFNPICCFLLFNVMDWLGRSLTSYFLWPDEDSQQLLPLLVCLRFLFVPLFMLCHVPQHARLPIIFRQDAYFITFMLLFAVSNGYLVSLTMCLAPRQVLPHEREVAGALMTFFLALGLSCGASLSFLFKALL
Protein: AP-4 complex subunit mu (Adaptor protein complex AP-4 subunit mu) (Adaptor protein-4 mu-adaptin) (Adaptor-related protein complex 4 subunit mu) (At-muC-Ad) (Mu4-adaptin) (Q9SB50)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Subcellular location: Golgi apparatus, trans-Golgi network {ECO:0000250}. Membrane, coated pit {ECO:0000250}. Note=Associated with the trans-Golgi network. {ECO:0000250}.
Interaction partners:
- AP-4 complex subunit epsilon
- AP-4 complex subunit sigma
- AP-1 complex subunit gamma-1
- Chlorophyllase-1
- Chlorophyllase-2
- AP-1 complex subunit gamma-2
- Beta-adaptin-like protein A
- AP-1 complex subunit sigma-2
- AP-1 complex subunit sigma-1
- Beta-adaptin-like protein C
Sequence:
MMISQFFVLSQRGDNIVFRDYRAEVPKGSTETFFRKVKFWKEDGNAEAPPIFNVDGVNYFHVKVVGLYFVATTRVNVSPSLVLELLQRIARVIKDYLGVLNEDSFRKNFVLVYELLDEVIDFGYVQTTSTEVLKSYIFNEPIVVSPARLQPIDPAAIFTQGAKRMPGTAVTKSVVANDPGGRRREEIFVDIIEKISVTFSSSGYILTSEIDGTIQMKSYLSGNPEIRLALNEDLNIGRGGRSVYDYRSSSGSGVILDDCNFHESVRLDSFDSDRTLSLVPPDGEFPVMNYRMTQEFKPPFHVNTLIEEAGRLKAEVIIKIRAEFPSDIIANTITVQMPLPNYTSRASFELEPGAAGQRTDFKESNKMLEWNLKKIVGGGEHTLRAKLTFSQEFHGNITKEAGPVSMTFTIPMYNVSKLQVKYLQIAKKSSSYNPYRWVRYVTQANSYVARI
Protein: V-SNARE coiled-coil homology domain-containing protein (A8WFN4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MALANQACQYILYPFTSCFNLCQKTAFSDHGLGVYMASQTEMEKYTMCSEIAEQTGESLGELFVPCEMPEQPKNNSFLKGVSSIFGGTPRNDPNDIDAILSENMGVKNSSGVNPMRSVARTIPGPSVQMDRAQAGGVSAGQAAAMALQNLNERTEKLNATVDATENLKNNAMSLSSRTGKLVEKYEKKKWYNF
Protein: Aquaglyceroporin (PfAQP) (Aquaporin-1) (Q8II36)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:A0A509APT1}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase
- glycerol kinase
- NADH-cytochrome b5 reductase, putative
- cAMP-dependent protein kinase regulatory subunit
- Haloacid dehalogenase-like hydrolase, putative
- Oocyst capsule protein
- Glideosome-associated connector
- Zinc finger protein, putative
- 26S proteasome regulatory subunit 4 homolog
- Uncharacterized protein
Sequence:
MHMLFYKSYVREFIGEFLGTFVLMFLGEGATANFHTTGLSGDWYKLCLGWGLAVFFGILVSAKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKIPQFAWETSRNPSISLTGAFFNELILTGILLLVILVVVDENICGKFHILKLSSVVGLIILCIGITFGGNTGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVFCQFYDKVICPLVDLANNEKDGVDL
Protein: Galactitol 1-phosphate 5-dehydrogenase (EC 1.1.1.251) (P0A9S3)
Organism: Escherichia coli (strain K12)
Function: Converts galactitol 1-phosphate to D-tagatose 6-phosphate.
Interaction partners:
- PTS system galactitol-specific EIIB component
- PTS system galactitol-specific EIIA component
- D-tagatose-1,6-bisphosphate aldolase subunit GatZ
- Putative permease IIC component
- Putative phosphotransferase enzyme IIB component SgcB
- Putative deaminase AgaI
- ATP-dependent 6-phosphofructokinase isozyme 1
- D-tagatose-1,6-bisphosphate aldolase subunit GatY
- ATP-dependent 6-phosphofructokinase isozyme 2
- Putative phosphotransferase IIA component SgcA
Sequence:
MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP
Protein: Orexin receptor type 2 (Hypocretin receptor type 2) (Q5TMB6)
Organism: Gallus gallus (Chicken)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MSGTQPEDVSPPCRDWTSSPELNETREPFLNPSADYDDEEFLRYLWKEYLHPKGYEWALIAGYIVVFIVALVGNVLVCIAVWKNHHMRTVTNYFIVNLSLADILVTITCLPATLVVDITETWFFGHHLCKAIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIIIIWIVSCIIMIPQAIVMECSSVFPGLANKTTLFTVCDEHWGAEVYPKMYHTCFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQKKWKSLQSSAQQRGLGQSTKSKISAVAAEIKQIRARRKTARMLMVVLLVFALCYLPISILNILKRVFGMFNHADDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCIFGIHSHHDERLTRGRASTESRKSLTTQISNFDNVSKHSEHVLLTNINTLTANGITATFSPLKSMELHLHIPGVNVSSNLDEAVRISAGCTGNTENAEWDKFVPSVTKLTSMELQQG
Protein: GDP-fucose transporter 1 (Solute carrier family 35 member C1) (Q8BLX4)
Organism: Mus musculus (Mouse)
Function: Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP. Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q96A29}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Solute carrier family 35 member C2
- Alpha-
- Nucleotide sugar transporter SLC35B4
- GDP-mannose 4,6 dehydratase
- CMP-sialic acid transporter
- Adenosine 3'-phospho 5'-phosphosulfate transporter 2
- Adenosine 3'-phospho 5'-phosphosulfate transporter 1
- Nucleotide sugar transporter SLC35D1
Sequence:
MNRAPLKRSRILRMALTGVSAVSEESESGNKPFLLRALQIALVVSLYWVTSISMVFLNKYLLDSPSLQLDTPIFVTFYQCLVTSLLCKGLSTLATCCPGMVDFPTLNLDLKVARSVLPLSVVFIGMITFNNLCLKYVGVPFYNVGRSLTTVFNVLLSYLLLKQTTSFYALLTCGVIIGGFWLGIDQEGAEGTLSLTGTIFGVLASLCVSLNAIYTKKVLPAVDHSIWRLTFYNNVNACVLFLPLMIVLGELRALLAFTHLSSAHFWLMMTLGGLFGFAIGYVTGLQIKFTSPLTHNVSGTAKACAQTVLAVLYYEEIKSFLWWTSNLMVLGGSSAYTWVRGWEMQKTQEDPSSKDGEKSAIRV