wanglab/gogpt-training-data huggingface dataset:
Protein: Protein OBERON 1 (Potyvirus VPg-interacting protein 2) (Q9S736)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that acts together with OBE2 for the maintenance and/or establishment of both the shoot and root meristems, probably by controlling the expression of the meristem genes such as WUS, PLT1 and PLT2 and of genes required for auxin responses. Promotes cell meristematic activity via the WUSCHEL-CLAVATA pathway. Involved in the development of the basal pole and in auxin-mediated root and vascular development in the embryo. Confers sensitivity to turnip mosaic virus (TuMV) probably by promoting viral movement and multiplication via interaction with TuMV VPg.
Subcellular location: Nucleus {ECO:0000269|PubMed:18403411}. Nucleus, nucleoplasm {ECO:0000269|PubMed:30338215}. Note=Colocalizes with heterochromatin. {ECO:0000269|PubMed:30338215}.
Interaction partners:
- Nucleolar complex-associated protein 3
- Cysteine/Histidine-rich C1 domain family protein
- PHD finger protein MALE MEIOCYTE DEATH 1
- Uncharacterized protein At3g24150
- Histone acetyltransferase
- Nucleolar complex-associated protein 2
- Chromatin remodeling protein SHL
- Protein SLOW WALKER 2
- Trihelix transcription factor ENAP1
- PHD finger protein ALFIN-LIKE 5
Sequence:
MGTSSGSNLPHQMLPPRQQLQTSLSLVSSDPHLSRSNSGIVRESPAESASSQETWPTSKSIMGRKTDSGKTGPDSHDQHVIRHVSIADKVSLRDIARERLDIVAERMHRLPEEYLEELKNGLKAILEGNGAQPIDEFMFLQKFVQTRSDLTSKTLVRAHRVQLEVLVVINTGIQAFLHPNINLSQSSLIEIFVYKRCRNIACQNELPADGCPCEICANRKGFCNLCMCVICNKFDFAVNTCRWIGCDVCSHWTHTDCAIRDGEISMGVSPKSVSGMGEMLFKCRACNHTSELLGWVKDVFQHCAPNWDRESLMKELDFVSRIFRGSEDTRGRKLFWKCEELMEKIKGGLAEATAAKLILMFFQEIELDSPKSLESGEGGGTIAPQDACNRIAEVVKETLRKMEIVGEEKTRMYKKARMGLEECEREVEEKAKQVAELQMERQKKKQQIEEVERIVRLKQAEAEMFQLKANEAKVEAERLERIVKAKKEKTEEEYASNYLKLRLSEAEAEKEYLFEKIKEQESGGNGGEASQAVMYSKIREMLHGYNASSPRVDPRSNQRNPFRSNP
Protein: Docking protein 3 (Downstream of tyrosine kinase 3) (p62(dok)-like protein) (DOK-L) (Q9QZK7)
Organism: Mus musculus (Mouse)
Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- Tyrosine-protein kinase CSK
- Growth factor receptor-bound protein 2
- TYRO protein tyrosine kinase-binding protein
Sequence:
MESVEPPVKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWDVRDGGLGPAGDRSTGPSRRGERRVIRLADCVSVLPADGESCPRDTGAFLITTTERSHLLAAQHRQSWVDPICQLAFPGTGECSSGSGQAESPKRGFVPMEENSIYSSWQEVTEFPVIVQRTEATSRCQLKGPYLLVLGQDDIQLRETSKPQACFSWPYRFLRKYGSDKGVFSFEAGRRCDSGEGLFAFSSPRAPDICGVVAAAIARQRERLPELAMSPPCPLPRALSLPSLEPPGELREVAPGFELPTPRKLPLTDPGPQSLPLLLSPTQEGPASGLYASVCKQTSKHTGTAEHLYENVCMLEASPGLTNGGPEAQEGPPGGRSPLGSPIYHNTEDLSWPGSAQDSNLEAQYRRLLELELDEAGSAGRSGAQAGIKAKLVTLLTRERKKGPAPCDRP
Protein: Glyceraldehyde dehydrogenase small chain (EC 1.2.99.8) (Glyceraldehyde dehydrogenase subunit C) (Glyceraldehyde dehydrogenase subunit gamma) (Q4J6M5)
Organism: Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Function: Component of the glyceraldehyde dehydrogenase which is involved the nonphosphorylated Entner-Doudoroff pathway. Catalyzes the oxidation of D-glyceraldehyde to yield glycerate. When the artificial electron acceptor 2,6-dichlorophenol-indophenol (Cl2Ind) is used, the enzyme shows a broad substrate range (glyceraldehyde-3-phosphate, formaldehyde, acetaldehyde, propionaldehyde and isobutyraldehyde), but is most active with D-glyceraldehyde. It is not known which acceptor is utilized in vivo.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10095793}.
Interaction partners:
- Glyceraldehyde dehydrogenase medium chain
- Glyceraldehyde dehydrogenase large chain
- Carbon monoxide dehydrogenase large chain
- Carbon monoxide dehydrogenase large chain
- Carbon monoxide dehydrogenase
- Carbon monoxide dehydrogenase large chain
- Carbon monoxide dehydrogenase large chain
- Carbon monoxide dehydrogenase medium chain
- Aldehyde oxidase
- Aldehyde oxidase and xanthine dehydrogenase
Sequence:
MLVVKKGEGVKVRVRVNGVWYEKYVSPRTLLVDFIRDELGLTGTKVGCDTTTCGACTVIMNGKSVKSCTVLAAQADGAEITTIEGLSSDSKLHPIQEAFKDNFALQCGFCTAGMIMQTYFFLKEHPNPTEEEVRDGIHGNICRCTGYQNIVKAVLDASKRLRS
Protein: ribonucleoside-diphosphate reductase (EC 1.17.4.1) (F8RDD9)
Organism: Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)
Interaction partners:
Sequence:
MDSAAPALSPALTAHTGQSATADLAIQIPKCPDPERYFYTSQCPDINHLRSLSILNRWLETELVFVGDEEDVSKLSEGELSFYRFLFAFLSAADDLVTENLGGLSGLFEQKDILHYYVEQECIEVVHSRVYNIIQLVLFHNNDQARREYVAGTINHPAIRAKVDWLEARVRECASVPEKFILMILIEGIFFAASFAAIAYLRTNNLLRVTCQSNDLISRDEAVHTTASCYIYNNYLGGHAKPPPERVYGLFRQAVEIEIGFIRSQAPTDSHILSPAALVAIENYVRFSADRLLGLIHMKPLFSAPPPDASFPLSLMSTDKHTNFFECRSTSYAGAVVNDL
Protein: DNA-directed RNA polymerase subunit alpha (PEP) (EC 2.7.7.6) (Plastid-encoded RNA polymerase subunit alpha) (RNA polymerase subunit alpha) (P56762)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- DNA-directed RNA polymerase subunit beta'
- DNA-directed RNA polymerase subunit beta''
- DNA-directed RNA polymerase subunit beta
- Small ribosomal subunit protein uS8c
- Small ribosomal subunit protein uS14c
- Large ribosomal subunit protein bL20c
- Small ribosomal subunit protein uS14m
- Large ribosomal subunit protein uL2cz/uL2cy
- Large ribosomal subunit protein bL36c
- Small ribosomal subunit protein bS18c
Sequence:
MVREKVKVSTRTLQWKCVESKRDSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRAKSENIPHDYSNIAGIQESVHEILMNLNEIVLRSNLYGTRNALICVQGPGYITARDIILPPAVEIIDNTQHIATLTEPIDLCIELKIERNRGYSLKMSNNFEDRSYPIDAVFMPVENANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHQASRNLINLFIPFLHVEEETFYLENNQHQVTLPFFPFHNRLVNLRKKKKTKELAFQYIFIDQLELPPRIYNCLKKSNIHTLLDLLNNSQEDLIKIEHFHVEDVKKILDILEKK
Protein: CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) (Q9NZN8)
Organism: Homo sapiens (Human)
Function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of embryonic stem (ES) cell identity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21299754}. Nucleus {ECO:0000305|PubMed:21299754}.
Interaction partners:
- CCR4-NOT transcription complex subunit 10
- CCR4-NOT transcription complex subunit 1
- CCR4-NOT transcription complex subunit 11
- CCR4-NOT transcription complex subunit 6
- CCR4-NOT transcription complex subunit 3
- CCR4-NOT transcription complex subunit 8
- CCR4-NOT transcription complex subunit 9
- CCR4-NOT transcription complex subunit 7
- CCR4-NOT transcription complex subunit 4
- CCR4-NOT transcription complex subunit 6-like
Sequence:
MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQPSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF
Protein: Zinc finger protein 346 (Just another zinc finger protein) (Q9UL40)
Organism: Homo sapiens (Human)
Function: Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity. May bind to specific miRNA hairpins.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:15254228}. Cytoplasm {ECO:0000269|PubMed:15254228}. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5.
Interaction partners:
- Myc proto-oncogene protein
- Little elongation complex subunit 2
- Cytochrome c oxidase subunit 1
- Interferon-induced, double-stranded RNA-activated protein kinase
- S-phase kinase-associated protein 1
- HBS1-like protein
- Cullin-1
- Interleukin enhancer-binding factor 3
- Uncharacterized protein
- Salivary acidic proline-rich phosphoprotein 1/2
Sequence:
MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED
Protein: Mitochondrial S-adenosylmethionine carrier protein (SAM carrier) (Solute carrier family 25 member 26) (Q70HW3)
Organism: Homo sapiens (Human)
Function: Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S-adenosylmethionine (SAM) into the mitochondria.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:14674884, ECO:0000305|PubMed:26522469}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cysteine desulfurase
- Mitochondrial carrier homolog 1
- Mitochondrial carrier homolog 2
Sequence:
MDRPGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFSKAGGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
Protein: Mucin-1 (MUC-1) (Episialin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)] (Q02496)
Organism: Mus musculus (Mouse)
Function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
Subcellular location: Apical cell membrane; Single-pass type I membrane protein. Note=Exclusively located in the apical domain of the plasma membrane of highly polarized epithelial cells. After endocytosis, internalized and recycled to the cell membrane. Located to microvilli and to the tips of long filopodial protusions (By similarity). {ECO:0000250}.; SUBCELLULAR LOCATION: [Mucin-1 subunit beta]: Cell membrane. Cytoplasm. Nucleus. Note=On EGF and PDGFRB stimulation, transported to the nucleus through interaction with CTNNB1, a process which is stimulated by phosphorylation. On HRG stimulation, colocalizes with JUP/gamma-catenin at the nucleus (By similarity). Some transportation to the nucleus when infected with C.jejeuni. {ECO:0000250}.
Interaction partners:
- Epidermal growth factor receptor
- Catenin beta-1
- Galectin-3
- Sialoadhesin
- Sialic acid-binding Ig-like lectin 12
- Mucin-4.
- Receptor tyrosine-protein kinase erbB-2
- Intercellular adhesion molecule 1
- Mucin-2
- CD209 antigen-like protein A
Sequence:
MTPGIRAPFFLLLLLASLKGFLALPSEENSVTSSQDTSSSLASTTTPVHSSNSDPATRPPGDSTSSPVQSSTSSPATRAPEDSTSTAVLSGTSSPATTAPVNSASSPVAHGDTSSPATSLSKDSNSSPVVHSGTSSAATTAPVDSTSSPVVHGGTSSPATSPPGDSTSSPDHSSTSSPATRAPEDSTSTAVLSGTSSPATTAPVDSTSSPVAHDDTSSPATSLSEDSASSPVAHGGTSSPATSPLRDSTSSPVHSSASIQNIKTTSDLASTPDHNGTSVTTTSSALGSATSPDHSGTSTTTNSSESVLATTPVYSSMPFSTTKVTSGSAIIPDHNGSSVLPTSSVLGSATSLVYNTSAIATTPVSNGTQPSVPSQYPVSPTMATTSSHSTIASSSYYSTVPFSTFSSNSSPQLSVGVSFFFLSFYIQNHPFNSSLEDPSSNYYQELKRNISGLFLQIFNGDFLGISSIKFRSGSVVVESTVVFREGTFSASDVKSQLIQHKKEADDYNLTISEVKVNEMQFPPSAQSRPGVPGWGIALLVLVCILVALAIVYFLALAVCQCRRKSYGQLDIFPTQDTYHPMSEYPTYHTHGRYVPPGSTKRSPYEEVSAGNGSSSLSYTNPAVVTTSANL
Protein: Chemotaxis protein (EC 2.7.3.-) (Q0PBM1)
Organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Interaction partners:
- protein-glutamate methylesterase
- Histidine phosphotransferase
- histidine kinase
- MCP-type signal transduction protein
- Methyl-accepting chemotaxis signal transduction protein
- MCP-type signal transduction protein
- Methyl-accepting chemotaxis signal transduction protein
- Methyl-accepting chemotaxis signal transduction protein
- Bipartate energy taxis response protein cetA
- MCP-type signal transduction protein
Sequence:
MFDENIVKTGSNEMELVDFRIFKQGHDKVYEGIYGVNVSKVREIIKIPSLTELPGVPDYIEGIFDLRGVVIPVVNLAKWMQITEPESTMLKPRVIITEFSNILIGFIVHEAKRIRRINWKDIEPATFSTGSGALDKGKITGVTRIENDEVLLILDLESVVEDLGIYAPKTDIDFGKIEKFTGTALILDDSMTARKRVKEMMQQMGFQVVEAKDGVEGINKLEELSQIYGESLNDTLKIIVSDVEMPQMDGFHFAARIKEDPRFKDIPIVFNSSLSNEFMNEKGVQEAGGEGYLVKFNASDFFNEIAKVIKKHQSQEQG
Protein: t-SNARE coiled-coil homology domain-containing protein (Q2UA95)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004409}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004409}.
Interaction partners:
- V-SNARE coiled-coil homology domain-containing protein
- t-SNARE coiled-coil homology domain-containing protein
- t-SNARE coiled-coil homology domain-containing protein
- Soluble NSF attachment protein
- t-SNARE coiled-coil homology domain-containing protein
- Vacuolar protein sorting-associated protein 51 homolog
- Protein transport protein SEC22
- Vacuolar protein sorting-associated protein 45
- Vesicular-fusion protein SEC18
- Synaptobrevin homolog YKT6
Sequence:
MDHADPFLHVQADVLATLQTAKPLFSSYLRIRSLAKSPSNPELQQARSELETTLTELTTDLDDLVESVRAIEQDPYRYGLELEEVQRRRKLVEDVGGEIEQMREELQKAVTSSAATGSARLDAPTGSSPSGLPNPSDFDNVLSPSADDRGDDYYAALEQQRQMELMHEQDEQLDGVFRTVGNLRQQADDMGRELEEQAVMIGEVDTLADRVGGKLQSGVSKIKYIVRKNEDTMSSFCIAVLIFVLVLLLILVIAL
Protein: IP10831p (Q9VB92)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- RE23868p
- RH58587p
Sequence:
MRELFFLAALLVAGNALPIEERINGENGWFVPQEDGTFQWMDKKDAKELLENISPLEFRSNEVSFYLYTKQNPTEGQEITADASSIVASHFNKDHGTRFVIHGWKGKYTDSMNVDITKAWLSKGDFNVIVVNWARSQSVDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVIGHSLGAHVAGYAGKQVGQKRVHTIVGLDPALPLFSYDNPDKRLSSEDAFYVESIQTNGGVKGFVKPIGKAAFYVSGGRKQPGCGVDLAGTCSHARSVIYYAEAITENSFGAIQCQDYQAALDNECGSSFSSVRMAEDTNAYNVEGHFYVPVNSEAPFGQTE
Protein: Cell wall protein DAN1 (Covalently-linked cell wall protein 13) (Delayed anaerobic protein 1) (P47178)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the cell wall.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:10322008}. Membrane {ECO:0000269|PubMed:10322008}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:10322008}. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Interaction partners:
- Eukaryotic translation initiation factor 5A-2
- ATP-dependent permease AUS1
- Cell wall protein TIR4
- Sterol uptake control protein 2
- Transcriptional activator/repressor MOT3
- Cold shock-induced protein TIR1
- Repressor ROX1
Sequence:
MSRISILAVAAALVASATAASVTTTLSPYDERVNLIELAVYVSDIGAHLSEYYAFQALHKTETYPPEIAKAVFAGGDFTTMLTGISGDEVTRMITGVPWYSTRLMGAISEALANEGIATAVPASTTEASSTSTSEASSAATESSSSSESSAETSSNAASTQATVSSESSSAASTIASSAESSVASSVASSVASSASFANTTAPVSSTSSISVTPVVQNGTDSTVTKTQASTVETTITSCSNNVCSTVTKPVSSKAQSTATSVTSSASRVIDVTTNGANKFNNGVFGAAAIAGAAALLL
Protein: SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Anthracycline-associated resistance ARX) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2) (Q9Z1F9)
Organism: Mus musculus (Mouse)
Function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention. {ECO:0000250}.
Interaction partners:
- SUMO-activating enzyme subunit 1
- SUMO-conjugating enzyme UBC9
- Small ubiquitin-related modifier 1
- Small ubiquitin-related modifier 2
- Small ubiquitin-related modifier 3
- Ubiquitin-conjugating enzyme E2 D2
- BTB/POZ domain-containing protein KCTD2
- Ubiquitin-like protein NEDD8
- NEDD8-conjugating enzyme Ubc12
- E3 SUMO-protein ligase PIAS3
Sequence:
MALSRGLPRELAEAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEANADQQNEPQLGLKDQQVLDVKSYASLFSKSIETLRVHLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDSPEKVGPKQAEDAAKSIANGSDDGAQPSTSTAQEQDDVLIVDSDEEGPSNSTDCSGDDKARKRKLEENEAASTKKCRLEQMEDPDDVIALD
Protein: 2-oxoadipate dioxygenase/decarboxylase, chloroplastic (EC 1.13.11.93) (2-hydroxyglutarate synthase) (Q9LMJ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Protein ELC
- 4-hydroxyphenylpyruvate dioxygenase
Sequence:
MISLHSSAIKASLYGSFPSSLRSTLSVSFSAGSLIRLPSVGKRNLSVVVSSGRDSSMSSNNVSRGSSSKVAAESFFRSVLGQMETVYLNRNPTPKSVLELVRSVDDQQLCYDHLAFRTFGIGGYGIDSLASFFLDYGYTPMDELKFPAKKLRALWFAPPNASAVPGGSGVNGPLPRVFISELLVDQMSSQTQDVIRKYTEASPNGKKYAGLSSALGTLTWEKPLSSEFEQLARESEYAAWTLVNGYALNHVTISVHRLKSHLNKIKKLNQFLEEKGIKLNSEGGVLKVSPDGGLQQSSTVADSISFKFADGVTKSIPCSYIEFAERLVLPQYQNIPESEIQESHRRDGFEVGNADKIFESTFQEQLSRRTG
Protein: Regulator of G-protein signaling 4 (RGP4) (RGS4) (P49799)
Organism: Rattus norvegicus (Rat)
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-5
- Guanine nucleotide-binding protein G
- Neurabin-2
- Guanine nucleotide-binding protein subunit alpha-11
- Regulator of G-protein signaling 7-binding protein
- Guanine nucleotide-binding protein G
- Calmodulin-like protein 4
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHSSSHSKKDKVVTCQRVSQEEVKKWAESLENLINHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLTNPSSCGAEKQKGAKSSADCTSLVPQCA
Protein: Protein APEM9 (ABERRANT PEROXISOME MORPHOLOGY 9) (Protein DAYU) (Q8W4B2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in peroxisome biogenesis and matrix protein import. Required for pollen maturation and in vivo germination via its role in peroxisomal function, which partially involves jasmonic acid biosynthesis. Transported to peroxisomes via the interaction with PEX19-1. Required for peroxisomal protein import by acting as an anchoring protein for the AAA ATPase complex, which consists of PEX1 and PEX6.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:21487094}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Peroxisomal ATPase PEX6
- Pollen-specific leucine-rich repeat extensin-like protein 1
- Peroxisomal membrane protein 13
- Pollen-specific leucine-rich repeat extensin-like protein 2
- Peroxisome biogenesis protein 5
- Peroxisome biogenesis protein 7
- Peroxisome biogenesis factor 10
- Peroxisome biogenesis protein 16
- Protein JINGUBANG
- Glyoxysomal processing protease, glyoxysomal
Sequence:
MEATDIWGEIERSESYLVCSMYEEAESLSSSILKRIFGNIDVLSDEASQGDHQFHDMLESAGMVLVQSLHGIGRTVEIVNELRDVFGEVAAIPVQVLLTGVCLQISNGSYLGVRDILEEFFRIWVYKDNHYILNDAGVSTKGFHAKNCLDIDEYMEVVELYTFGVLAKFSNDMGLAISWVEKAALPEERRQGILRRLHSLLSLKTASSFEENSKDSSYAVVNNKKSLGNEKNDEIDSFLKLSKQHEPWSLWSSHPLSLKVGNTQFSMSRGKVAVSLVGLIICYALKRKRAALIRIIRRQMESTRKAIVDFWKLAFSYQVNPLAAIQSIPSTTT
Protein: NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1) (P48163)
Organism: Homo sapiens (Human)
Function: Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:8187880}.
Interaction partners:
- Pyruvate carboxylase, mitochondrial
- Fumarate hydratase, mitochondrial
- Malate dehydrogenase, mitochondrial
- Pyruvate kinase PKM
- Citrate synthase, mitochondrial
- Pyruvate kinase PKLR
- L-lactate dehydrogenase A chain
- L-lactate dehydrogenase A-like 6A
- L-lactate dehydrogenase A-like 6B
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Sequence:
MEPEAPRRRHTHQRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEEMKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ
Protein: Transmembrane protein (F4IRF0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MFSVLVFPLLLNCLVYLFNAIAIKPEITNLILESSLLPMTDPNTPEFAAHLMRVFVDFRQFVNSLYIFIAVSSIINLLSTLVMVHASALTHKDDSFEIKDFPILTLKYWKGPLVTNFYIVLFSLGYWFLFFIVLFSIVFFSTKLDSLAAKSRALFIVFAVFESYLAIVWNLSMVISILEDTYGIQALGKAAKIVKGMKPKLFLLNLFFGLLSFGLVQILRLVDWSSSFSVTLTTGLVLMSSVFVVRMFQLVTYTVAYFQCKSLQGQDSLRDVEYTKLSSTTLMGGLP
Protein: Uncharacterized protein At1g66480 (Q6NLC8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT 1
- J domain-containing protein required for chloroplast accumulation response 1
- Protein PLASTID MOVEMENT IMPAIRED 2
- Protein PLASTID MOVEMENT IMPAIRED 1
- Protein PLASTID MOVEMENT IMPAIRED 15
- At1g21660
- Protein CHUP1, chloroplastic
- Uncharacterized protein At5g17350
- At3g10120
- At1g64700
Sequence:
MGNSITVKRKRAKVMKIDGETFRIKTPVTAREVTADYPGYVLLDSQAVKHFGVRSKPLEPNQTLKPKKTYFLVELPKLPPETTAVDTENKLPYRRVMSGIHVGAKERLDMLMLSRRTVSDVTIGRSDGGDGFGPELGPGHTSVRLRLPRSQITKLMEENNNDASAIAEKILGIYMERSGELGGGRGGVDGRRELGSGEIKAREKQVSFAGEGGRELPVLWSRSGK