wanglab/gogpt-training-data huggingface dataset:
Protein: Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit (EC 2.4.1.15) (Trehalose-6-phosphate synthase) (UDP-glucose-glucosephosphate glucosyltransferase) (Q9UUI7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Alpha,alpha-trehalose-phosphate synthase
- Cytosolic neutral trehalase
- Trehalose-phosphatase
- Trehalose-phosphatase
- Probable UTP--glucose-1-phosphate uridylyltransferase
- Probable UTP--glucose-1-phosphate uridylyltransferase
- Uncharacterized protein C922.04
- Putative alpha,alpha-trehalose-phosphate synthase 106 kDa subunit
- Probable gluconokinase
Sequence:
MGRQFICSIYLPYTINFHLDELEGNHESHPAITHQEKVTQTHRDSVKIDDILTRLSISKSESGQATPVLTPQLEGMNDYFSLGPSKRTGGSMTPGLGAMSPIPGSGRSSPLYTQPRSRATSPSRVRQADRFAAPGIGAGALPIRRKRRDSLAKSVALFESARWSVERGVVGNSGLFHAVDAAVRDHGLQNPLWVGLLGMPTESLSEKTKNAISGALLVKHQSLVVYTSDSNFEGHYNHYCRKILWPSLHYQHNEIFSFFHEESNWDDYVAVNRAFADALIKNYKTGDTIWVNDYHLLLVPNMVRERIPSAIIGLFIHVSFPSSEVFRCFARRKELLQGMLGSNLIGFQTEEYKRHFLQSCSRVLYAESTFDRILLDDRYIDVYAHPIGADPVLVDKWLENPETLEVKEVLEKRYANLNIFVGCDKMDPIRGIREKLLAFEQFLYDNPEYQKNTILIQTSTFTEEQKEYGVAISDIVTRINSAFGDFSLDHLPVTILSSDLSYPQYLALLSVADAFIVTSLREGMSLTCHEFILTQRQKKSPLIVSEFIGCASMFSNGAFIVNPWSTLELSLSMKKALTLSTNERNQRYSNCLDVVLTHSASNWVTGFETKLKKSWTSQQKRDFSRLPRFTLNFIGNRYDHAKKRLLILNFDGNAVTWEGRHEFVDFHYGYMVSILSKLIADDRNIVYIASCLEEDELESLFMHVPGVGLIAENGCYVLPHYAENVHQSWIRLYKKQQMDWREPLHDIIQYYSERTPGSSLIDHGFAMEFNYVKAENRENGLRSAGELASSINETQHGCRAVPLDGRVLCEPTTISKATAANYIMTHLIKNPEELDLILVAGNNRTDESVFAWANKSKVSSFTVSMGVGNTEAKAYTDGIPSFFNVLNSLCA
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q38G44)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MLLLLALTATIIRNDAQAQIHEAPKIIASACDSTRQTEHVLTQIKSKIETAFQQIVLGKKTSAKLSVAAAASTGEKAVAYAALAASAAVKLQAAEQNLQSNLDALLKGAAAAAELTATEELVSEAADLSLEARSGARTSTASGTQGGLPLRFARFGGGKSKCDTAKEAADQRKAAPGTKGGDKISFAHLQNRPKIGNDKKLAALCGDDNTPPNNCDGSADADLTYFEITTGTLLTEKMKQYNKGPQPTDGYTPDTPEPTALLPRETYVTGRLNIIKQAGHAYDSITFTADSLKNSALVTDGTTQALLETTLLTQKEREQTDIRQNKLEEITARLYGKAGTDVKARIWEPIEIIPIQAEATEDNKATELKHLTDIGKLRRAAAFYLAKQATKAETAAVQKATESTEKTERAKTTENRKYGDKKDEVCKATDEKDCDKNKCEWNKEKNECKVKESAFIISVSIKAILLLKYFGFSVKYLIFFQINSIKLIGFFDFERILYFERLW
Protein: N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] (P20933)
Organism: Homo sapiens (Human)
Function: Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
Subcellular location: Lysosome.
Interaction partners:
- Gamma-glutamylcyclotransferase
- Glutaminase kidney isoform, mitochondrial
- Glutathione hydrolase light chain 3
- Inactive glutathione hydrolase 2
- Glycine N-acyltransferase
- Glutathione hydrolase 1 proenzyme
Sequence:
MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAWRALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI
Protein: Transmembrane protein 19 (Q96HH6)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Seipin
Sequence:
MTDLNDNICKRYIKMITNIVILSLIICISLAFWIISMTASTYYGNLRPISPWRWLFSVVVPVLIVSNGLKKKSLDHSGALGGLVVGFILTIANFSFFTSLLMFFLSSSKLTKWKGEVKKRLDSEYKEGGQRNWVQVFCNGAVPTELALLYMIENGPGEIPVDFSKQYSASWMCLSLLAALACSAGDTWASEVGPVLSKSSPRLITTWEKVPVGTNGGVTVVGLVSSLLGGTFVGIAYFLTQLIFVNDLDISAPQWPIIAFGGLAGLLGSIVDSYLGATMQYTGLDESTGMVVNSPTNKARHIAGKPILDNNAVNLFSSVLIALLLPTAAWGFWPRG
Protein: Probable RNA 3'-terminal phosphate cyclase-like protein (Q54S38)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9Y2P8}.
Interaction partners:
- BMS1-like ribosome biogenesis protein
- RNA-binding protein pno1
- WD40 repeat-containing protein
- Periodic tryptophan protein 2 homolog
- U3 snoRNP protein
- U3 small nucleolar ribonucleoprotein protein
- Ribosomal RNA-processing protein 7 C-terminal domain-containing protein
- Bystin
- WD40 repeat-containing protein
- WD40 repeat-containing protein
Sequence:
MLKFQGSTHFRQRIICSTLSGKAIRITNIRDEDEKPGLRDYEASFLRLVDKITNGSKIEINSTGTQITYIPGIIIGGKGITHECGTVRGIGYFVEALICLGPFAKAPLDITLNGITNNDIDLTIDTIRTTTLPIIRKFGIEEGLIIKIIKRGAPPNGGGSVNFKCPIVPHLKAIQLIDEGKIRRIRGIAYATRISPQFSNRVLDKAKGLLLEYTPDVYISSDHYKGNESGLSPGYGLTLVAETTTGCCLSAECMSNTGIATTEQQLQKQKSTSETPEDLGERTAFALLEEIFNGGCIDSHNQSLALLFMVLCPEDISKVRLGKITPYTIEFIRQLRDFFGVTFKIEPDQNSKTVLFTCLGIGYKNMARSTF
Protein: Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Q8VIJ5)
Organism: Rattus norvegicus (Rat)
Function: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:8034696}. Cytoplasm {ECO:0000269|PubMed:8034696}.
Interaction partners:
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- Glutamine--fructose-6-phosphate aminotransferase 1
- Hepatitis A virus cellular receptor 1 homolog
- Cystatin-C
Sequence:
MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPSALTKEEEKKQPDEEPMDMVVEKQEESEHKSDNQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCINDIAPMQTDEQANKEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL
Protein: At5g64090 (Hyccin) (Q9FMI8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
- Protein NPGR1
- Phosphatidylinositol 4-kinase alpha 1
- Phosphatidylinositol 4-kinase alpha 2
- Protein NPGR2
- Protein NPG1
- Uncharacterized protein
- ARM repeat superfamily protein
- Uncharacterized protein
- ARM repeat superfamily protein
Sequence:
MDFSVKPSGGSPSPSSSTSSSTPHRFKSVTTPTATAAAVSGFSPSAAADRDPMHSWWESVSKQRSRILSLSSLLSGDSHFEDGDVTPISSLADSDRPALSLLSSRAAYSLISNSLCNPASGSGSDPLCQWLYETYLSSDPPLRLVVLSFFPLLVGMYLSRIHSSDSTSLPSLSGFEAVLLAIYAAEVKARAGKPILVHIPDLSQPSLYHTPRNGVDKSRDSNPTASVGVLSPQLEPQIAVKSTKRASIVGVGLQCYFKEISQMPAWSKLEFCKFSASWAGQDCDCKEKIDEDEDKVLALTNGFGDSSSFNGSSGRSLEIEEDFDRLAIRENEEQLSSNGGGGGVGRGVRIPLPWELFQPTLRILGHCLLSPLNTEDVKDAASNAVRSLYARASHDLNPQAILATRSLVNLDTSARTSGKTVAAETVNGSSNVNTPSKAKKPEILLASK
Protein: Nucleolar protein Dnt1-like N-terminal domain-containing protein (A0A1D8PJL3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Ras family GTPase
- Tyrosine-protein phosphatase CDC14
- Serine/threonine protein kinase
- Mob1p
- Protein phosphatase PP2A regulatory subunit B
- Mitosis inhibitor protein kinase SWE1
- Cell cycle protein kinase DBF2
- Chromatin-binding protein
Sequence:
MSKIKLKALLIPKEFEQIDASNIDPRKYVKFLYLVDRTANIESLEEGLITRFSKRYPRERKLRVLAFQNKDLCDLDPEFAVEDVFNESNDELRVLVDNKFKSITYTPEPAISTPINFSQAETIRGGVYSTVDITDDKTTPKKSKQSPLSSPVSLAPPPESRSNRKIPQKKKSVSSLKQRITSGMLEAPPATPMNNPDKVYFDERSFTSPKKKQQKAKKNDSFVASSSLDEVSSGDEYKESEESAAETADYEPEEEEKIQPEELLSMYEELDFHENDDLPLSQTSNPKHSTINKALQIDMVEGNPAMYLSRTKRRAAREANLVFTSSKKAAKTPSSTPKPASTIKTTPKPGKVQKSTPTTKQKHTSPVVGVNGQSKSLPKPTQTAGTEKKSSISTSSKQAKTTVGKAQTKATPVTHTKTALTTTSQSSNKALPKSTNKPSVSKSTLEDLYDRMKVFGQKVKTLMVHGEDGNIIGYEKIPNDFGDGIQLAHDISSEAIDTALRLTVQKDSQDSDIVKTEEKVSNPEPISSNPEPSLQPVEKIVSISSDTEVKSKTSANNLDSEDTDDIVIKPPVKNRKTGSTKAASKDLDSDDDLKEIASATAPPNVTSTKPISKESDSHVANDNGSDSDDIDIKAADAAFVPAKISTATSAPISTNVNSNVANDNGSDGIDIDIKAADAAFVPAKISTAASASIVNNNAANESDSDDIDIDIKTASAAFVPVKTGTASSASIVNSNVANESDSDGVDIDIDIKAAGQAFVPVKTGTTEALAPIVNRKVTNDSDSDDMDIDIKTAGAAFVPTRSGTTETSAPIAIIVDSSEEETGNNKTGNNTISISREQLKTFAKIINKSKMGSGSFSNNSSNGQDVVDNKILPDTAPSAFAGMVEISDDGNGISGNNTPNRLNYDDNESYIPKSFASNFRAHERKTQALGSLQIVHQDPVVDKTPTKNYELASDNMLSYIYVGDSGGEDINAVGRGIDDRSRGYNKSSDPSSPFGKTDTSSSFLFGGGGSSTNANTSIPKPAFGAGDLFATKPNNGNGTNNRNDYSMGNNNGNSSISVGGINANNTTGSEWNNNNTHRNGTGATSGSVLSNKTSNSNDQNSSIPSAQQQANNNINSATRAALSRLSSLQNLVNSNKRSRPDSESEESDDGEDEEDEDHDEPERVRKKSKLIASTPIPKPIMTPLSGNGNKLRSNLIPWSSKAKPIIPKXNTST
Protein: Probable RNA-binding protein 19 (RNA-binding motif protein 19) (F1QF98)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- BMS1 ribosome biogenesis factor
- IMP U3 small nucleolar ribonucleoprotein 4)
- PWP2 small subunit processome component.
- Bystin-like.
- Ribosome biogenesis protein wdr12
- Apoptosis-antagonizing transcription factor
- Pescadillo
- Nucleolar MIF4G domain-containing protein 1
- WD repeat domain 36
- ATP-dependent RNA helicase
Sequence:
MSRLIVKNLPNGMKEDRFRKMFADFGTLTDCALKFTKDGKFRKFGFVGFKTEEDAQKALKHFNKSFVDTSRVTVELCTDFGDPNKARPWSKHTRQPSSKKDTEEKKTHEQGEKEKKKPKKILNVLGDLEKDESFQEFLAVHQKRGQVPTWANDTVEATAVRPEMEKKKEKKQKAAVEDDYLNFDSDESEESSDDGEDAADEEDKQDNEKEALKTGLSDMDYLRSKMVEKSDMLDEKDDDSSASAADENEEDEGKEEEESIVQHADSAYESGEKTSSQKSTRPAIEPTTEFTVKLRGAPFNVKEQQVKEFMMPLKPVAIRFAKNSDGRNSGYVYVDLRSEAEVERALRLDKDYMGGRYIEVFRANNFKNDRRSAKRSEMEKNFVRELKDDEEEEDVAESGRLFIRNMPYTCTEEDLKEVFSKHGPLSEVLFPIDSLTKKPKGFAFVTYMIPENAVSALAQLDGHTFQGRVLHVMASRLKKEKADQGPDAPGSSSYKRKKDAKDKAASGSSHNWNTLFLGTSAVADAIAEKYNTTKSQVLDHESDGSLAVRMALGETQIVQETRQFLLDNGVSLDSFSQASGERSKCVILVKNLPSGVQVADLEALFSPHGSLGRVLLPPSGLTAIVEFLEPTEAKRAFMKLAYTKFQHVPLYLEWAPVAVFTTPSAPRPEPQTKEKSAVKNDSVQNEEEEEEEEEDDQILPGSTLFIKNLNFITSEETLQKTFSKCGVVKSCTISKKRDKAGKLLSMGYGFVQYKTPEAAQKAMRQLQHCTVDEHQLEVKISEREVKSGVAQAKRKKQTARKQTTSKILVRNIPFQATVKELRELFCTFGELKTVRLPKKGIGGSHRGFGFIDFLTKQDAKKAFSALCHSTHLYGRRLVLEWADAEETVDDLRRKTAQHFHDAPKKKRKAEVLEGILEQMEVGDGDGE
Protein: Large ribosomal subunit protein uL2cz/uL2cy (50S ribosomal protein L2, chloroplastic) (P56791)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL16c
- Large ribosomal subunit protein uL14c
- Small ribosomal subunit protein uS7cz/uS7cy
- Large ribosomal subunit protein bL20c
- Large ribosomal subunit protein uL6c
- Large ribosomal subunit protein uL16m
- Small ribosomal subunit protein uS8c
- DNA-directed RNA polymerase subunit alpha
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS19c
Sequence:
MAIHLYKTSTPSTRNGAVDSQVKSNPRNNLICGQHHCGKGRNARGIITARHRGGGHKRLYRKIDFRRNAKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGRGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPVTPWGYPALGRRTRKRKKYSETLILRRRSK
Protein: bZIP transcription factor 60 (OsbZIP60) (Q8LIB3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor involved in endoplasmic reticulum (ER) stress response. Acts as ER stress sensor and activates the transcription factor BZIP50 and the chaperone BIP1.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:24153418}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000305|PubMed:24153418}. Note=The bZIP domain is translocated into the nucleus in response to ER stress. {ECO:0000305|PubMed:24153418}.
Interaction partners:
- Kinetochore protein NDC80
- Kinetochore protein SPC25
- Kinetochore protein SPC25
- bZIP transcription factor RISBZ5
- bZIP transcription factor RISBZ2
- bZIP transcription factor RISBZ1
- bZIP transcription factor RISBZ4
- Os12g0601800 protein
- bZIP transcription factor RISBZ3
- Os08g0163100 protein
Sequence:
MAEPDLLAPFADLPFPPGDDFPDFPTLGDDAFALEDFDLDDLDFDFDVDLFPPDAPPPVTTSSSSSAAGSPEAGTSSAGDGGSKNEESADSSSPSRSGSDGGGGKDGKDDEAKRRARLVRNRESAHQSRQRKKQYVEELEGKVKVMQATIADLTARISCVTAENAALKQQLGGAAGAGAAAPPPPMPMYPAVYPLPMPWIHPAYAMRGSQVPLVPIPRLKTQQPASTPEPPAKKARKTKKVAGVSLLGLLFLMMVCGCLVPAVNRMYGAAYTGEGAAIVPSHHGRILAVEGPQNSVSNGVDPKVPQNGSETLPALLYLPRNGKHVKINGNLVIKSIVASEKASSRLSNYGEKGSGNQGKEETSLAIPGYVAPLEAGEVMDSAKGMNELMALAPGDGSIYREDDGMLPQWFSEAMSGPMLNSGMCTEVFQFDLSPTTADANGIVPVYSGSVTNTSQNYTENLPSGPVQKVKNRRISYSEAIPLRGSTSNDTDHFKAPPKNHSQSHAGRKPVSSVVVSVLADPREASDRDGEGRISSNSLSRIFVVVLIDSVKYVTYSCVLPFKSHSPHL
Protein: C3H1-type domain-containing protein (Q388X0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTMDIIEGDSMDNELLPMWAIDEIWEQWKQSNELCGSTNFPLSVSTENCANANLTKVFDAEFKCLYEVPSHLIVHMPSARLNITRLVACRNYKSYEPSSCTMGSGCKFVHADVDYNTLETHPIHVNYIWRHESECTYERLPAGEVLEVLSADMTTVNLIPSEQVLNTRGACARHDIAEPLIRCKYFETNQTCFTGERCNFIHVVCVDPNAQGAFKRAPKVVAEPNASACTSPQHSNNIKGKKSVVGNNGSGFNKEEHSAGMRKAPEEGRHDGGSGWVPNVSSPSFEPSPVVQMALRQGLNGTCGLPQNAPQKPTSGPRSPSATTPPMGDTNTQEILAALRTAGVCGTGYASATTGRTVPQDQMNTLLSQLVSIMAQQAAAPRTITVAPSPQLDDPAAVGTLLFLPRGAAEAVAVQPVFDGSFLSTVVTLGAGQRRCTGTIQQPRPQPLGDVWQLYNSQIPGHDGTVPLNWPYAR
Protein: Uncharacterized oxidoreductase Rv1714 (EC 1.-.-.-) (P9WGQ3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Cyclase
- Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3
- Beta-D-galactosidase Rv1717
- 3-keto-5-aminohexanoate cleavage protein
- Probable conserved two-domain membrane protein
- HTH-type transcriptional regulator Rv1719
- Probable fatty acid synthase Fas
- Probable conserved integral membrane protein
- Probable short-chain type dehydrogenase
Sequence:
MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLAELVNGAGIDDAAVVTCRPDSLADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLLEQGQGGSVVLVSSVRGGLGNAAGYSAYCPSKAGTDLLAKTLAAEWGGHGIRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPEDFVGALIYLLSDASSFYTGQVMYLDGGYTAC
Protein: Regulator of length of O-antigen component of lipopolysaccharide chains (Q8XBV8)
Organism: Escherichia coli O157:H7
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Mg
- Mg
- Uncharacterized protein
- Oxidoreductase subunit
- Oxidoreductase subunit
- YdhW family oxidoreductase system protein
- YdhW family oxidoreductase system protein
- HTH-type DNA-binding transcriptional activator EutR
- HTH-type DNA-binding transcriptional activator EutR
- Chaperone NapD
Sequence:
MSSLNIKQGSDAHFPDYPLASPSNNEIDLLNLISVLWRAKKTVMAVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKTFTKLRVLDLDIKIDRTEAFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNASKKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISALVVKESIENVRNKLEIKTQFEKEKLAQDRIKMKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGADGIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKANINDVNFTPFKYQLSPSLPVKKDGPGKAIIVILSALIGGMVACGSVLLRYAMASRKQDAMMADHLV
Protein: Taiman, isoform F (Taiman, isoform H) (M9MRG5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSIAAAENAGLSPSDLPDHWASGTSNPSTSTSSSSSSSISASGSNNNKYNSGNISVCNLPRSSPAAATAAVTLSSAAGGIGSNLLSGLHHGLAPGTHPLQRATAASGGGAGAGGVAGASTAAALTLQQHQHQQQQQQQQQQAQHQHQHQHQQQTQQQQLAYQHQQLQQQIISHRSIQNKAAATAAAQTANLAAALQRSAAIMNAVASPISANSANSATSGRKIRRKTDSKVNLPQSQINKCNNEKRRREAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTSTNNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPEPSLLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYSGDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGLGGAGGAAAGKKRSISTKVRMLVKDTRTATQTSSNCEEKPLRQSGHQDKYEEVVLIAAPVKDDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPTALREPFKQHLQTWVGRLWQDLCHPHDLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGAPDVYVHVKANSRLFLNQTPGEGDFIMSVQTLLNSENDMNSSNTGAGSGGLGLGQLCAMAPSPSLASSLLSSLSMDGLHGGTGSGSSSSPAASGMLPTHLLGGLVGGGQQGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASPAPAEHSFYGSDTFEFDIAAHSSSFELDPSGGVGAWTDSRPNSRASVATPVSTPRPPSGHGFSPAVCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQQSNNNSSSSNPLLGGGLPNGVGGMLLSQQQQQQQTPPQQQQQQQQQESSERLRHLLTKSQSMAGGLGGLGDDEKYFKPEGSEEEKHASGGFKMGGQPGGMGMFGPMGSMGRGVGNSSMLHKAGNSQNPMLLKLLNEKSEDDDGNGSGGGPGSMNNSRQSELMRQLKNPDGGSHGMHRNSASGNMSTEDLKAMLKIQSDPSLNRKRSLNEPDDDPSAKRSEDKPSKLCTQNKMLAKLLQNPPKIPKAPNPEQPLQVKTLPDITSSTVSSTLAAPGNLISAGSTGPKAAANRNRKQQQQQQQQQQQQQQQQVAGIPSQQQQQQPNDVYLSQQQQQQLQSPQLAFQHQQLATTATTSITTAASTSAAAAAAAAILGEGDSELSKLLDSVMEYYPDDTPIVTNAPSEASAINDIQKSLMLDVESAAFGNDLNQQLMMTQQQQHQQQQQQQQLLALQLAQQQQQQRQQHLQQPPAYPGMLNMQQQQHQQQQQQNQQHIMQRLEAMRNQGNQGFQRPPPMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQQLAAAQQKERLLQQQQKQQLLVPENATGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQLSPNFAQTLMQQQLSPGRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQQQLAYQQQQVGDGGRSNTPFGSNSGMQSPGMQNSPQQWGSGGGGGGGPGGPLPSGNAGRTLQQHNPMLIAQLQGVSPYNARQYQQNQRRGLNSPGAVGPGGNPAAQAALQRQNSFQGQGGGGATTPDGSGVGFGGPQSPYGTNVNVFQQQQLQRLQRQGSVPQATQHLPAGGGGSVAGGNANSEFVKQELRAVVSVRAQQAAAAATGGAGVGGGVAQRGQTPQSPLQQGSVIGGGGGIVGGVNSTNTMGNVTPTGSGNVSNSMLNTPPDPTLSFSFETPDFFTSSATR
Protein: Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6) (Q3TWW8)
Organism: Mus musculus (Mouse)
Function: Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:12549914}. Nucleus speckle {ECO:0000250|UniProtKB:Q13247}.
Interaction partners:
- SRSF protein kinase 1
- Transformer-2 protein homolog beta
- Transformer-2 protein homolog alpha
- Serine/arginine-rich splicing factor 1
- Nuclear RNA export factor 1
- RNA-binding protein 25
- Splicing factor U2AF 65 kDa subunit
- Serine and arginine-rich splicing factor 11
- Serine/arginine-rich splicing factor 3
- Heterogeneous nuclear ribonucleoprotein M
Sequence:
MPRVYIGRLSYNVREKDIQRFFSGYGRLLEIDLKNGYGFVEFEDSRDADDAVYELNSKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDKYGKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSHSPLPAPPSKARSMSPPPKRASRSRSRSRSRSRSSSRD
Protein: ATP synthase subunit O, mitochondrial (A0A3B3ITX4)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
MAQFVRNLVEKTPALVNAAVTYSKPRLATFWYYAKVELVPPTPAEIPRAIQSLKKIVNSAQTGSFKQLTVKVPQLKRDEETLETVLRRLKR
Protein: Cellular tumor antigen p53 (Tumor suppressor p53) (Q761V2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}. Nucleus, PML body {ECO:0000256|ARBA:ARBA00004322}.
Interaction partners:
Sequence:
YSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSD
Protein: Ran-binding protein M homolog (AtRanBPM) (F4HYD7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22676313}. Nucleus {ECO:0000269|PubMed:22676313}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:22676313}. Note=Associates predominantly in the form of large cytoplasmic complexes. {ECO:0000269|PubMed:22676313}.
Interaction partners:
- Protein RMD5 homolog
- Protein MAEA homolog
- WD repeat-containing protein 26 homolog
- WD repeat-containing protein WDS homolog
- Protein GID8 homolog
- ARM repeat superfamily protein
- Protein yippee-like
- Protein yippee-like At5g53940
- At3g08890
- ARM repeat superfamily protein
Sequence:
MNSSPPPANSANGDTTNNGENGQDLNLNFLDKIRLSAKRDAKEDEGEELPTELNTINSAGGFLVVSPDKLSVKYTNTNLHGHDVGVVQANKPAPIKCLTYYFEIFVKDSGIKGQIAIGFTKESFKMRRQPGWEVNSCGYHGDDGYLYRGQGKGEPFGPKFTKDDAVGGGINYASQEFFFTKNGTIVGKIPKDIRGHLFPTVAVHSQNEEVLVNFGKKKFAFDIKGYEASERNKQQLAIEKISIPPNIGYGLVKTYLLHYGYEETLDAFNLATKNTVPPIHIDQENAIDEDDSSYALKQRKNLRQLVRNGEIDTALAELQKLYPQIVQDDKSVVCFLLHCQKFIELVRVGKLEEGVNYGRLELAKFVGLTGFQDIVEDCFALLAYEKPEESSVWYFLEDSQRELVADAVNAAILSTNPNKKDVQRSCHLQSHLEKLLRQLTVCCLERRSLNGDQGETFRLRHVLNNNR
Protein: Heterogeneous nuclear ribonucleoprotein H1 (H0YBK1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA
Protein: GTP-binding protein rho3 (O13928)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in controlling cell shape and septation. Regulates cell separation by modulating the function of the exocyst complex. Involved in post-Golgi vesicle transport. Involved in driving sexual development in a palmitoylation-dependent manner.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12415007, ECO:0000269|PubMed:12930742}; Lipid-anchor {ECO:0000269|PubMed:12415007, ECO:0000269|PubMed:12930742, ECO:0000269|PubMed:23843742}. Note=Found at the cell periphery and the growing tips of interphase cells. Localized to the division site during cell division.
Interaction partners:
- Exocyst complex component exo70
- Formin-3
- Exocyst complex component sec8
- Probable Rho-type GTPase-activating protein 4
- Probable Rho-type GTPase-activating protein 3
- Rho GDP-dissociation inhibitor
- Rho guanine nucleotide exchange factor gef3
- Exocyst complex component sec15
- Exocyst complex component exo84
- Exocyst complex component sec10
Sequence:
MSSCFGSKKKPIYRKIVILGDGAAGKTSLLNVFTKGYFPQVYEPTIFENYIHDIFVDGNSIELSLWDTAGQEEYDQLRSLSYSDTHVIMICFAVDSRDSLENVITKWLPEVSSNCPGVKLVLVALKCDLRGADEEQVDHSKIIDYEEGLAAAKKINAVRYLECSAKLNRGVNEAFTEAARVALAAQPRGTKDGADESHGTGCIIA
Protein: Transcription factor 15 (TCF-15) (Meso1) (Paraxis) (Protein bHLH-EC2) (Q60756)
Organism: Mus musculus (Mouse)
Function: Early transcription factor that plays a key role in somitogenesis, paraxial mesoderm development and regulation of stem cell pluripotency. Essential for the mesenchymal to epithelial transition associated with somite formation. Required for somite morphogenesis, thereby regulating patterning of the axial skeleton and skeletal muscles. Required for proper localization of somite epithelium markers during the mesenchymal to epithelial transition. Also plays a key role in regulation of stem cell pluripotency. Promotes pluripotency exit of embryonic stem cells (ESCs) by priming ESCs for differentiation. Acts as a key regulator of self-renewal of hematopoietic stem cells (HSCs) by mediating HSCs quiescence and long-term self-renewal. Together with MEOX2, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells. Acts by forming a heterodimer with another helix-loop-helix (bHLH) protein, such as TCF3/E12, that binds DNA on E-box motifs (5'-CANNTG-3') and activates transcription of target genes.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:23395635}.
Interaction partners:
- Homeobox protein MOX-2
- Homeobox protein MOX-1
Sequence:
MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGLEAARRGPGPGSGRRASNGAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGDAADDGQPCFRAAGGGKSAVPAADGRQPRSICTFCLSNQRKGGSRRDLGGSCLKVRGVAPLRGPRR