wanglab/gogpt-training-data huggingface dataset:
Protein: Teichoic acid translocation permease protein TagG (P42953)
Organism: Bacillus subtilis (strain 168)
Function: Part of the ABC transporter complex TagGH (TC 3.A.1.34.1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Teichoic acids export ATP-binding protein TagH
- Teichoic acid poly
- Teichoic acid glycerol-phosphate primase
- Glycerol-3-phosphate cytidylyltransferase
- Probable undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase
- N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase
- Poly
- UDP-N-acetylglucosamine 2-epimerase
- Minor teichoic acid biosynthesis protein GgaB
Sequence:
MNDLLRILREQITSFPLILRLAAYETKSKYQMNYLGVLWQFLNPLIQMLAYWFVFGMGIRKGGPVTTGAGEVPFIIWMLAGLIPWFFISPTILDGSNSVFKRINMVAKMNFPISSLPSVAIASNLFSYMIMMVIYIIVLLVNGVFPSVHWLQYIYYFICMIAFMFSFSLFNSTISVLIRDYQFLLQAVTRLLFFLLPIFWDVNAKLGQSHPELVPVLKLNPLFYIIEGFRNSFLDGAWFFHDMKYTLYFWLFTFLLLLVGSILHMKFRDKFVDFL
Protein: Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18) (P05523)
Organism: Escherichia coli (strain K12)
Function: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG) and its derivatives such as guanidinohydantoin:C and spiroiminodihydantoin:C, however it also acts on thymine glycol:G, 5,6-dihydrouracil:G and 5-hydroxyuracil:G. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Cleaves ssDNA containing an AP site.
Interaction partners:
- Endonuclease III lyase)
- DNA polymerase I
- Adenine DNA glycosylase
- Dephospho-CoA kinase
- 8-oxo-dGTP diphosphatase
- Endonuclease 4
- Exodeoxyribonuclease III
- UvrABC system protein A
- DNA mismatch repair protein MutL
- Uracil-DNA glycosylase
Sequence:
MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q9PW62)
Organism: Xenopus laevis (African clawed frog)
Interaction partners:
Sequence:
MSNNALVIEDKPPPPPMRINSTIGGGNTNDWNFGTKPLSTNQEEKEKKKKKGQKNNKKDKKDRLEISSPFGYEHIYHVGIDPATGEFTGMPNQWARLLKHANISKIDQKKNPQAVLDVLNFYSSETTSKSQKYMSFTDNSREAYDSIAILGEDANPVSEAAEVPPVPEAEDGEVAPAFPPRPEHTKSIYTRSVIEPPVPPLAAKSSAENGTSATDGAESSVDKTKKKPKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYIAVDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKHPNIVNYLDSYLVGEELWVVMEYLAGGSLTDVVTETCLQEGEIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGAVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQQPEKQSSAFRDFLSRCLEMDVEKRVSARDLLQHPFLKIAKPLSSLTPYIITGKQIAKGGH
Protein: DNA repair protein Rad9 (Q4QF86)
Organism: Leishmania major
Interaction partners:
Sequence:
MCVCVCVCVSLSERVEHAPTKQRSCLPAEKFDHNGLSTSTFTHNARAAAETPAKLAKSRDIHRRLRRPAFPHNSHPHYHHHHRHHRHPVLFPYRDESGSHLQRMSLQFTVSGPNIRVLLSILTCVSRLGDAVYIVGLSDGIEISAVSPGRNGHIAVRVHKRCFDRFLLELPSRRSGADDGSGLATSDAAAEGRADDAGADGPKPYLCLLTKTLVATVLRQHNTNVQSLDFQYRTAESSDSAAAAAAASDAGNDSADADQCLWKGRTDADVVRWHCTYARSLTKTFLLRLAEGEPTSVYADLSRYRFEVCGDARAYGSLLASLPSSANQCALTLPESGGLELRSVRQAGSSSSSSSSAAAAAAASGRESGSAAAPSGNIRAADGSSTVVTAFESTFTLFRFFEPAASPSATDADGAAMVTEYGPSEVPQTPFPHTPPPPPPPPQQQQSPRRDSVLSAPDPAPSATVTAGFIPLPGKTFDVKPFKNAAWLAEQLGVQLHLLTGEEGMPIIIASITPEEVQKRRIASSGVMLARHESLPGTGGAGARPFLVTNNAPSVPVPAPISFILYVAALDSAPSGGRASGSGGAPGGAADTSIATAISSAVNTPRPSTHQRTLKGDGGAPAAVAATPTPGYGDGENGERDGMPVSSGNSTTSGTLSHVEASFASTNAATAAAGMVGRLSRESNNTVGSAYATPRPTASPSDLVMVMTGGDTPGTRSGDAGGVHAARKSVDFLTGVTASSLPMNSAVAMTGAAPPSASLPPSPSHTPTATALNSMYPLDFEAFVRTYTSANEVGEEDAQDAELREFLASCVASMSRGPTQN
Protein: Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1) (O08755)
Organism: Mus musculus (Mouse)
Function: Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. Stimulates the expression of Onecut3 in the developing endoderm.
Subcellular location: Nucleus.
Interaction partners:
- Hepatocyte nuclear factor 1-beta
- Hepatocyte nuclear factor 3-beta
- Nuclear receptor subfamily 1 group D member 1
- Transcription factor SOX-9
- Hematopoietically-expressed homeobox protein Hhex
- Hepatocyte nuclear factor 4-alpha
- CCAAT/enhancer-binding protein alpha
- Neurogenin-3
- Pancreas transcription factor 1 subunit alpha
- Homeobox protein Nkx-6.1
Sequence:
MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVGHRGSHLPPAHPRSMGMASLLDGGSGGSDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSGSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGGSNSGSSSSSSSTCTKA
Protein: GroES-like zinc-binding alcohol dehydrogenase family protein (Putative quinone reductase) (Quinone reductase-like protein) (Q9LXZ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Calcium-transporting ATPase 1
Sequence:
MEALVCRKLGDPTATNPGSPESPVEVSKTHPIPSLNSDTSVRVRVIATSLNYANYLQILGKYQEKPPLPFIPGSDYSGIVDAIGPAVTKFRVGDRVCSFADLGSFAQFIVADQSRLFLVPERCDMVAAAALPVAFGTSHVALVHRARLTSGQVLLVLGAAGGVGLAAVQIGKVCGAIVIAVARGTEKIQLLKSMGVDHVVDLGTENVISSVKEFIKTRKLKGVDVLYDPVGGKLTKESMKVLKWGAQILVIGFASGEIPVIPANIALVKNWTVHGLYWGSYRIHQPNVLEDSIKELLSWLSRGLITIHISHTYSLSQANLAFGDLKDRKAIGKVMIALDHKTALSSKL
Protein: Protein GrpE (HSP-70 cofactor) (HSP24) (Heat shock protein B25.3) (P09372)
Organism: Escherichia coli (strain K12)
Function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Chaperone protein DnaJ
- Chaperone protein DnaK
- Chaperonin GroEL
- Chaperone protein ClpB
- Co-chaperonin GroES
- ATP-dependent protease ATPase subunit HslU
- Curved DNA-binding protein
- ATP-dependent protease subunit HslV
- Chaperone protein HtpG
- Small heat shock protein IbpA
Sequence:
MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKVANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA
Protein: Sclerostin (Q9BQB4)
Organism: Homo sapiens (Human)
Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:20551380}.
Interaction partners:
- Low-density lipoprotein receptor-related protein 5
- Low-density lipoprotein receptor-related protein 6
- Dickkopf-related protein 1
- Tumor necrosis factor ligand superfamily member 11
- Parathyroid hormone
- Bone morphogenetic protein 4
- Osteocalcin
- Protein Wnt-3a
- Transcription factor Sp7
- Catenin beta-1
Sequence:
MQLPLALCLVCLLVHTAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY
Protein: DUF614 family protein (B0G108)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSNWEHGLCDCTSDIRVCCISYLWPQLQVMQQRATVDGRQCEITDCLFTALCFPCVTCLTRSQIREKHGIEGSGVMDCLTVCYCTLCVIHQQTMQLQAKGEKPSGLFMN
Protein: Uncharacterized protein YPR159C-A (Q8TGQ7)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MATLDFTTKPLALVIYMSVVLLLMVGVPLLFSS
Protein: GATOR1 complex protein NPRL2 (Gene 21 protein) (G21 protein) (Nitrogen permease regulator 2-like protein) (NPR2-like protein) (Tumor suppressor candidate 4) (Q8WTW4)
Organism: Homo sapiens (Human)
Function: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Subcellular location: Lysosome membrane {ECO:0000269|PubMed:28199306}. Note=Localization to lysosomes is mediated by the KICSTOR complex and is amino acid-independent. {ECO:0000269|PubMed:28199306}.
Interaction partners:
- Ras-related GTP-binding protein A
- KICSTOR complex protein kaptin
- GATOR1 complex protein NPRL3
- GATOR2 complex protein WDR59
- GATOR2 complex protein WDR24
- KICSTOR subunit 2
- KICSTOR complex protein ITFG2
- Nucleoporin SEH1
- GATOR1 complex protein DEPDC5
- GATOR2 complex protein MIOS
Sequence:
MGSGCRIECIFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSMEESKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQRPDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDVFQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVTREEQSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK
Protein: Homeobox protein ceh-51 (Q9U1R1)
Organism: Caenorhabditis elegans
Function: Required for mesoderm development, including specification of muscle and coelomocyte precursors.
Subcellular location: Nucleus {ECO:0000255|RuleBase:RU000682, ECO:0000269|PubMed:19605496}. Note=Nuclear localization most obvious in the 8 embryonic cells derived from the MS blastomere. {ECO:0000269|PubMed:19605496}.
Interaction partners:
- T-box transcription factor tbx-35
- T-box protein 37
- C2H2-type domain-containing protein
Sequence:
MSSSNYNINNGGDYYPLSSSNLNSTSAITNATVMEYSTMPSSSPGSMSSSPAYPAAYQAPSPCYVADPNQLYYQQQLAHNGNDMLVQAHAQAYQAQCFAWFQQQYSQLSPSSFPHPMVAHHAGFIPPPPSFLHHQHQQHPRAPSEKRRGARTPFSDSQLYALRTRFEQCDTIKVDERRKLGAVIGLSPEQIKIWFQNRRFKLRKEKYKQIKQDAVQQQKSAKEEAEEDQKHVIS
Protein: Uracil phosphoribosyltransferase 2 (UPRTase 2) (EC 2.4.2.9) (UMP pyrophosphorylase 2) (Q9HE15)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
Interaction partners:
- Uridylate kinase
- Putative uracil phosphoribosyltransferase urg2
- Putative purine nucleoside phosphorylase
- Orotidine 5'-phosphate decarboxylase
- Uridine kinase
- Golgi apyrase
- Pseudouridine-metabolizing bifunctional protein C1861.05
- Uracil phosphoribosyltransferase 1
- Protein urg3
- Uncharacterized protein C1683.06c
Sequence:
MSIPLEQPENVVVLRQTMYLLSLMTILRDQQTGHSEFVRTANLIINMLMQEALSALPYKKCLIKTSSGGTYTGVQPARDICGVSILRAGESMEYGLAAACNYSVPVGKLLVQRDETTFEAKLMFCKLPKDAQDRLVLLLDPLLATGNSVILAIQTLINKGIPEENIVFVNLIACNEGITNVFAKFPKLRMVTASIDPELNANKYVVPGCGDFGDRYFGTC
Protein: Protein E6 (Q9IR59)
Organism: Human papillomavirus 82
Subcellular location: Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04006, ECO:0000256|RuleBase:RU363123}. Host nucleus {ECO:0000256|HAMAP-Rule:MF_04006, ECO:0000256|RuleBase:RU363123}.
Interaction partners:
Sequence:
MFEDIRERPRTLHELCEACNTSMHNIQVLCVYCKKELCRADVYNVAFTELRIVYRDNTPYAACKKCLMFYSRIREYRRYSRSVYGATLEAITNKSLYELLIRCHRCQRPLGPEEKQKVVDDKKRFHEIAGRWTGQCANCRKPPRQRSETQV
Protein: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART) (P04161)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Bifunctional purine biosynthetic protein ADE5,7
- Phosphoribosylformylglycinamidine synthase
- Amidophosphoribosyltransferase
- Bifunctional purine biosynthesis protein ADE17
- Bifunctional purine biosynthesis protein ADE16
- C-1-tetrahydrofolate synthase, cytoplasmic
- Adenylosuccinate lyase
- Methylenetetrahydrofolate dehydrogenase [NAD
- Serine hydroxymethyltransferase, cytosolic
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
Sequence:
MARIVVLISGSGSNLQALIDAQKQGQLGEDAHIVSVISSSKKAYGLTRAADNNIPTKVCSLYPYTKGIAKEDKAARAKARSQFENDLAKLVLEEKPDVIICAGWLLILGSTFLSQLQSVPILNLHPALPGCFDGTTHAIEMAWRKCQDENKPLTAGCMVHYVIEEVDKGEPLVVKKLEIIPGEETLEQYEQRVHDAEHIAIVEATYKVLQQLHK
Protein: Small oligopeptide transporter, OPT family (Q4WZZ4)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKDKIVEPTVAVSDNSLADETAPDEVLKHLKHIKEQHQWDPNLPDDVAEELDVALHTDDKGARVGVAHELMEDSPYVEVRSAVPNYDEGGHTNTIRAWTIGLVFATLGSALNMLFSMRQPYIVIPSYVIQVIAYPVGVAWYKVMPNKQFKFFGIDCNLNPGPFSKKEHALIVIMSNATFAGGAAYATDVLLAQRAFYKQRFSWAFELLLCISTQTLGFGLAGFFHRFLVTPAAMIWPSTLINSALFNALHDRSKPDPQKVSGWTIGKYRLFLYCMIGSFVWYWFPGYIAPFLSTFAFITWIKPQSPIVNQLFGGWTGLSLIPITFDWTQISGFNFSPLISPWHAHMNTLIGMVIFFWITTMGLHYSGMWYGKYLPISDSNSYDNTAQRYQVSKILTPNYEFDQAKYEQYSPLFLSTTFALNYGLSFATIIAVLIHTGLFHGKELWARFRKFGEEEEDVHARLMSRFKTVPLWWYAVLSLVMIGMGLGVVLGYPTHLSWWAFFVSLIIAAVWFVPIGLVQATTNIQIGLNVITEFIIGYMQPGRPMAMMLFKTFGYITMSQGLYFCQDMKLGHYMKLPPRVTFAGQLVACLWSSIVQICTMNWALGAINNVCDPEQANHYTCPNGRVFFNASIIWGVIGPSRMFSPGQIYSGLMWFWLAGAILPVVIYLGARYWPKSPIRFLSAPVIFGGAGLIPPATPLNYLSWGIVGLVFNRHIRNRFRGWWMHYTYVLSAGLDVGLALCTILIFLTLQLTNTDFPSWWGTNIAADTMDASGSAIQVVLPEGETFGPKSWS
Protein: Spliceosome-associated protein, putative (Q584V6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- SURP motif domain-containing protein
- Splicing factor 3B subunit 10
- RNA helicase
- Pre-mRNA-processing factor 19
- Uncharacterized protein
- Small nuclear ribonucleoprotein SmD1
- Uncharacterized protein
- Splicing factor 3A, putative
- Cell division control protein, putative
- Splicing factor 3B subunit 1, putative
Sequence:
MKEAKKKKLLRRQRQEELRERTKFIRERLQNAEEVEVQYVLSSDSDGEKSPAGDVTSRAVAETGNVDVEDEDRVQLPSITVNEAAGSKSKKNKQQRQKMSWEALKLAVAQRYGSDVSAMVSEHDGNAEDPLFTVFLKSVRRTVPVPQHWNRLRAFMANQADREKATDLVPPEIALLGVERIRATRDKKASIDQVAFVSCFITGTPLQRKRFNVSLSRFGDVFYEGKWLPKGCHTPGVLSQRLRTGLGMGPHSPPPWLYGMQAMRRLPPAYPGLKVPGLNAPIPPGAQWGNGEGQWGQPPRTESNTFLFPGVMDEVAVEEAPPVYWGTVPPLTSSSGSHQQQKSVVSHSVQAQPTPATVSTTKTPAPVTTPPPAINPVPFHPQAYTPATAVGYVPTTPQEYVRVQDSTVGATVALGSVLVPKAAVGAATMNQQQRQQQPQQQPPAKQVVPPRAPTKF
Protein: 26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55) (O00232)
Organism: Homo sapiens (Human)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Interaction partners:
- Proteasome subunit alpha type-1
- Proteasomal ubiquitin receptor ADRM1
- 26S proteasome non-ATPase regulatory subunit 6
- Proteasome subunit beta type-4
- Proteasome subunit beta type-7
- 26S proteasome regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 4
- Ubiquitin carboxyl-terminal hydrolase 14
- Proteasome subunit alpha type-2
- 26S proteasome non-ATPase regulatory subunit 3
Sequence:
MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
Protein: Developmental protein PhdA (PH domain-containing protein) (O76765)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Sequence:
MRLERDELLLQALNYKSIKDKVIYSTVMKKAGGNKKGFLSRLFVLYKGFVIYYKTKTLLTSPEKPQGYIDLRECDPSKVKTILDDTDMTFQIVHRAGRTFLIKGEEPKPFRRFFEICKCVALKLTQITFTLPVEKQTLLNQILDCNMSKEDFKHNIELFLKDGFVFNVNLISQERTEEVKTLVKYILDLRKEEIAAQSRIAKITIESGGKKNLSMGAPPPTHAATPDLMVTLVIPPENEPIPEIIKIQNELHKIRLDIEEHRMNIFNIQIRDHVEVLKQRYPEK
Protein: Triplex capsid protein 2 (F5HIN9)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04019}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04019}.
Interaction partners:
Sequence:
MAAMEANIFCTFDHKLSIADVGKLTKLVAAVVPIPQRLHLIKHYQLGLHQFVDHTRGYVRLRGLLRNMTLTLMRRVEGNQILLHVPTHGLLYTVLNTGPVTWEKGDALCVLPPLFHGPLARENLLTLGQWELVLPWIVPMPLALEINQRLLIMGLFSLDRSYEEVKAAVQQLQTITFRDATFTIPDPVIDQHLLIDMKTACLSMSMVANLASELTMTYVRKLALEDSSMLLVKCQELLMRLDRERSVGEPRTPARPQHVSPDDEIARLSALFVMLRQLDDLIREQVVFTVCDVSPDNKSATCIFKG
Protein: Anti-sigma-factor antagonist (STAS) domain protein (Q2RIF5)
Organism: Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Interaction partners:
- Putative anti-sigma regulatory factor
- Anti-sigma-factor antagonist
- Serine phosphatase
- Anti-sigma F factor
- CheC, inhibitor of MCP methylation
- Serine phosphatase
- Putative anti-sigma regulatory factor
- Diguanylate cyclase
- Flagellar motor switch protein FliG
- Flagellar hook protein FlgE
Sequence:
MSSRVPILKVDDYWVVAIEETLHDQSVIQFKEELLHNITGVAGKGLVIDISALEVVDSFVTRVLIEISRLAELLGLPFVLTGIKPAVAITLTEMGLDLRGMATALNLQKGLDKLKNLARMEQR
Protein: Short chain oxidoreductase (CsgA), putative (AFU_orthologue AFUA_4G00910) (Q5BBP1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MSSFLVTGASRGLGLAFVQRLSALPVSEVSIVFATARSQSPELEELAKQSAGRVIVIKLEVTNETSIKQAATEVEDRLGGKGLDVLINNAGVCDYTPDGVKTLDNLEQIFSVNVLGVHWVTRAFIPLLQKGVQKKVVNISTTLASITLARASHGLPTPAYKVSKAAMNALTVQYALDYEKEGFTIFALSPGWLKTELGGGDAADLTADEGARLSLDIILGPSRGLNGQFTRIHLPGWENSRHQYDGSNAPW
Protein: Rho GTPase activating protein 33 (D4A9G6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MGRASACPLARPSWGARQSPPAAVRGGACGRPRAPHALPFVSPWRRRRRQRGLRTRARKPSGSEEATATMVARSTDSLDGPGESSVQPVPPTGGPGTKGKPGKRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPEREGPSLSGENELVFGVQVTCQGRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGARAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSEEASLNIPAVAAAHVVKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRGFQVGFFPSECVELFTERPGPGLKADAEGPLCGIPAPQGISSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGLGGAAAFREVRVQSVVVEFLLTHVEVLFSDTFTSAGLDPAGRCLLPRPKSLAGSSPSTRLLTLEEAQARTQGRLGTPTEPTTPKTPASPVERRKRERVEKQRKPGGSSWKTFFALGRGPSIPRKKPLPWLSGSRAPPQPSGSRPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGPAPAGSCESLSSSSSSSSSSSSSSSSESSAAGLGPLSGSPSHRTSAWLDDGDELDFSPPRCLEGLRGLDFDPLTFRCSSPTPGDPAPPASPAPPASASAFPPRATPQALSPHGPKPASPTALDISEPLAVSVPPAVLELLGAGGAPASATPTPALSPNPGLRPHLIPLLLHGAEAQLSDTCQQEISSKLAPTRGAPGQHSPGGMDSPLLPPALSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQGQGGTPPAPLSPFRRSLSLEVGGEPVGTSGSGLHPPSLAHPGAWAPGPTPYLPRQQSDGSLVRSQRPLGTSRRGPRGPSQVSAHLRASGAYRDTPEMAAQSPCSIPSQGSNPSFLSTPRECLPSFLGVPKQGLYSLGPPSFPPNSPAPVWRNSLGAPPALDRGENLYYEIGVGEGTYSGPSRSWSPFHSMPPDRLNASYGMLGQSPPLHRSPDFLLNYPPPPSCFPPDPLTHSVSQHLARRPTRPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPVPRLPQKQRAPWGPHNPHRVPGPWGSPEPFLLYRAAPPSYGRGGEVRGSLYRNGGHRGEGAGPPPPYPTPSWSLNSEGQTRSYC
Protein: Mannonate dehydratase (EC 4.2.1.8) (D-mannonate hydro-lyase) (P24215)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the dehydration of D-mannonate.
Interaction partners:
- D-mannonate oxidoreductase
- Uronate isomerase
- Altronate dehydratase
- 2-dehydro-3-deoxygluconokinase
- Altronate oxidoreductase
- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
- Starvation-sensing protein RspA
- 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
- Uxu operon transcriptional regulator
- Ribose-5-phosphate isomerase B
Sequence:
MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
Protein: Persephin (PSP) (O70300)
Organism: Mus musculus (Mouse)
Function: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.
Subcellular location: Secreted {ECO:0000250|UniProtKB:O60542}.
Interaction partners:
- GDNF family receptor alpha-1
- GDNF family receptor alpha-3
- GDNF family receptor alpha-2
- GDNF family receptor alpha-4
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Neurturin
- Glial cell line-derived neurotrophic factor
- Artemin
- GDNF family receptor alpha-like
Sequence:
MAAGRLRILCLLLLSLHPSLGWVLDLQEASVADKLSFGKMAETRGTWTPHQGNNHVRLPRALAGSCRLWSLTLPVAELGLGYASEEKVIFRYCAGSCPQEARTQHSLVLARLRGRGRAHGRPCCQPTSYADVTFLDDQHHWQQLPQLSAAACGCGG
Protein: L-ribulose-5-phosphate 3-epimerase UlaE (EC 5.1.3.22) (L-ascorbate utilization protein E) (L-xylulose-5-phosphate 3-epimerase) (P39305)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization.
Interaction partners:
- 3-keto-L-gulonate-6-phosphate decarboxylase UlaD
- L-ribulose-5-phosphate 4-epimerase UlaF
- 3-keto-L-gulonate-6-phosphate decarboxylase SgbH
- Ascorbate-specific PTS system EIIB component
- Ascorbate-specific PTS system EIIA component
- Ascorbate-specific PTS system EIIC component
- L-xylulose/3-keto-L-gulonate kinase
- L-ribulose-5-phosphate 4-epimerase SgbE
- Probable L-ascorbate-6-phosphate lactonase UlaG
- L-ribulose-5-phosphate 4-epimerase AraD
Sequence:
MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDDRLSRLNWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMSSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA