wanglab/gogpt-training-data huggingface dataset:
Protein: Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (robl/LC7-like protein) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (P62628)
Organism: Rattus norvegicus (Rat)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9NP97}.
Interaction partners:
- Cytoplasmic dynein 1 heavy chain 1
- Dynein light chain Tctex-type 1
- Cytoplasmic dynein 1 light intermediate chain 2
- Cytoplasmic dynein 1 light intermediate chain 1
- Dynein light chain Tctex-type 3
- Cytoplasmic dynein 1 intermediate chain 2
- Cytoplasmic dynein 2 light intermediate chain 1
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic dynein 2 intermediate chain 2
- Dynactin subunit 1
Sequence:
MAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYANLMHNFILKARSTVREIDPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPTE
Protein: Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Q5MD89)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P35917}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P35917}. Cytoplasm {ECO:0000250|UniProtKB:P35917}. Nucleus {ECO:0000250|UniProtKB:P35916}. Note=Ligand-mediated autophosphorylation leads to rapid internalization. {ECO:0000250|UniProtKB:P35917}.
Interaction partners:
- C-fos induced growth factor
- Vascular endothelial growth factor C
- Vascular endothelial growth factor A-A
- Lymphatic vessel endothelial hyaluronic receptor 1b
- Placenta growth factor
- Vascular endothelial growth factor Ab
- Protein tyrosine kinase 2ab
- Platelet-derived growth factor beta polypeptide a
- Angiopoietin 2b.
- Cadherin 5
Sequence:
MKRDFTFFCRIWIGIPFFSGLVNGFSMSPPTLDNTKDQLVINANDTLNITCRGQRILDWSWPEESLSKVEFTDRQGQQSPTDTPGYREIRLKECQGVAGKPYCKILILTNAQANDSGYYRCFYKDIKAVIDGTTAASIFVFVRDPEHPFIKRGDNDMETIFITDSETHIEVPCLVSDPDLKVTLFSLVPYPEPVDGSVVTWNNKKGWSIPRHIIQNTSTFIGFYCSISVQNSQHTSSIYVVQVIGLKFYEFKLFPEDSPVELMQGESLVLNCTALVDFNTGVDFQWDYPGKKENRLASLQPLRNVLDEATEISSILSIRNIHLDDSGYYTCWANTLEMKRELTTVVIVHEKPFISLDYRNGSVIEAKEGQKSVRLSVKVSAYPSPEIQWYKNGKLISSKNSSRFKVQQHSLQIRDVCKQDAGEYMLVLKNSPAALEKRLNFTLIVNVPPQIHEKEAAPPTNLYGKGTRQILTCTADGSPPASISWQWRPWSPCDLERTRRALRRRGGRDQSPFCHNWMDLDPEHAVNPIESIDTLTQMVDGKEKTVGRVVIQNASVPAMYKCLAENRVGKDERLIYFYVTTIPEGFDIEMEPSEDPLEQDLVQLKCNADNFTYENLRWYRLDPQTVPPELDCKSLHQYATFLEGQLSFQTTSNNWVLQLNITNIQLQDEGNYVCEVQNRRTGVKHCHRKYIPVKAMEAPRYRHNPTNHTVNVSESLQMNCDVEGTPFPQLSWFKDNQPLHQISGILLQDSNRTLSIQRVREEDAGLYTCSACNQKGCVQSSATVSVIGSDDKTNVEIVILIGTGVIAIFFWVLLLVIFCNVKRVNPADIKTGYLSIIMDPGEVPLEEQCEYLPYDSSQWEISRDRLRLGKVLGHGAFGKVIEASIFGHDKKSSANTVAVKMLKEGATASEHKALMSELKILIHIGNHLNVVNLLGACTKPNGPLMVIVEYCKYGNLSNFLRAKREFFLPYRDRSPKTQSQVRRMIEAGQASQSEHQPSTSSTNPPRVTVDDLWKTPLTIEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDYVRKGNARLPLKWMAPESIFDKVYTSQSDVWSFGVLLWEIFSLGASPYPGIQIDEDFCKRLKDGTRMRAPDNASPEIYGIMLACWQGEPRERPTFPALVEILGDLLQENSLPEIPFNVSQSSEDDGFSQASSRPPSQEEIRLACNTLPTRYYNCVPFAGCVMVGPSSTCHSRVKTFEELPMEMTSHKTQHDSQTDSGMVLASDELERFEHKHRGAMLTTATTGQSTDRLISCPSVSSSGSGGGLLRPVFFTQLSGQTFYNNEYGHLSEEGVSDYFSSSDQAV
Protein: Transcription factor atf-7 (cAMP-dependent transcription factor family member 7) (Q86MD3)
Organism: Caenorhabditis elegans
Function: Transcription factor which regulates the transcription of various genes, including those involved in innate immunity and oxidative stress responses. Binds to promoter regions of genes, probably at 5'-[GACGTCA]-3' consensus sequences. Together with transcription factor daf-19, involved in regulation of the serotonergic response of ADF neurons to pathogenic food. Modulates response to infection by the Gram-negative bacterium P.aeruginosa, acting downstream of the p38 signal transduction pathway effector serine/threonine kinase pmk-1. May act with transcription factor elt-2 to control p38 gene induction in response to bacterial infection. May be phosphorylated by pmk-1. Regulates transcription of the metallothionein gene, mtl-1, perhaps acting downstream of pmk-1.
Subcellular location: Nucleus {ECO:0000269|PubMed:20369020}. Chromosome {ECO:0000269|PubMed:30789901}.
Interaction partners:
- Transcription factor jun-1
- Mitogen-activated protein kinase pmk-1
- Transcription factor zip-2
- Transcription factor atf-2
- Dual specificity mitogen-activated protein kinase kinase sek-1
- Mitogen-activated protein kinase kinase kinase nsy-1
- Protein skinhead-1
- NAD
- ShKT domain-containing protein
- BZIP domain-containing protein.
Sequence:
MATTMMTSSASPPESGELDVASAVASAAAALISPMVMPTSMTNGKDMTKTSQILNEYFNMMVGKRVQLMGDTTSPFSLDTPNPKLMFTPLDLPTTAELMQRCLAVNPFEAKFREANQKISSGSMQPNTSGANQSLEALEANGGSQFSGSNAGTMSDLLLKIPQASLQHSPGIFSNMLLNAGDSEGTTRENLKTADISKLLSVAGDFSAQAPRTADVLNAVLDMHSDRLHTINYLNNKPDFSALLRSPSSSAPNSASVLTNAMAIPSTSGAPFPGTTLLVPPKTVSSYHSPLGASSQPPSTQKSPADGSWDHINGEKQIKKEIPYFNDDAMMLMERSNMSSSGSDQDQSADMSNAGSTASTSTGNPVGRPQNGTPGRGRGRGRSTTADMQPDERRNTILERNKAAAVRYRKRKKEEHDDMMGRVQAMEAEKNQLLAIQTQNQVLRRELERVTALLTERESRCVCLKGVPMSDEQHADHHHRNTNGMYSGSDMLNGLGQINGMQLKLPKLQ
Protein: Uncharacterized protein (Q384P6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLANYDYESDLRGRTDELGRAQHVDAYDKHPTFLESPYAGQEDLLRDAPQSYMDGPPPGYGGHDAYEHVDMNGGGYDLPLQPQAQTQAVDTRRLSKDRLARGGLNIFSWNTDAPTLNHPREVRERDCAELQRLRPVDSAAQRDKEVREKFEGNTQSRFLCFSESDSPGKRRGVRVFNPNNKNGNLNSGTGHENPIQNRFNEEPQPFKIRQQQPRPLPQQNLPPAGRATHSNRQESGGIPGFAGMGEGRQHNARRGRGSYRG
Protein: Neuronal acetylcholine receptor subunit beta-2 (Neuronal acetylcholine receptor non-alpha-1 chain) (N-alpha 1) (P09484)
Organism: Gallus gallus (Chicken)
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: Synaptic cell membrane {ECO:0000250|UniProtKB:P12390}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P17787}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor subunit alpha-5
- Neuronal acetylcholine receptor subunit alpha-3
- Neuronal acetylcholine receptor subunit alpha-2
- Acetylcholine receptor subunit alpha
Sequence:
MALLRVLCLLAALRRSLCTDTEERLVEYLLDPTRYNKLIRPATNGSQLVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVISYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCILITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMPPWVRTLFLRKLPALLFMKQPQQNCARQRLRQRRQTQERAAAATLFLRAGARACACYANPGAAKAEGLNGYRERQGQGPDPPAPCGCGLEEAVEGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTVGMFLQPLFQNYATNSLLQLGQGTPTSK
Protein: ATP-dependent permease PDR11 (P40550)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transporter involved in the uptake of sterol.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Oligomycin resistance ATP-dependent permease YOR1
- Metal resistance protein YCF1
- Transcription factor PDR3
- ABC transporter NFT1
- Transcription factor PDR1
Sequence:
MSLSKYFNPIPDASVTFDGATVQLEESLGAVQNDEESASEFKNVGHLEISDITFRANEGEVVLVLGNPTSALFKGLFHGHKHLKYSPEGSIRFKDNEYKQFASKCPHQIIYNNEQDIHFPYLTVEQTIDFALSCKFHIPKQERIEMRDELLKEFGLSHVKKTYVGNDYVRGVSGGERKRISIIETFIANGSVYLWDNSTKGLDSATALEFLSITQKMAKATRSVNFVKISQASDKIVSKFDKILMLGDSFQVFYGTMEECLTHFHDTLQIKKNPNDCIIEYLTSILNFKFKETSNSIVGLDTPSVVSEENQALNINNETDLHTLWIQSPYYKHWKAITSKTVQECTRKDVNPDDISPIFSIPLKTQLKTCTVRAFERIIGDRNYLISQFVSVVVQSLVIGSLFYNIPLTTIGSFSRGSLTFFSILFFTFLSLADMPASFQRQPVVRKHVQLHFYYNWVETLATNFFDCCSKFILVVIFTIILYFLAHLQYNAARFFIFLLFLSVYNFCMVSLFALTALIAPTLSMANLLAGILLLAIAMYASYVIYMKDMHPWFIWIAYLNPAMFAMEAILSNELFNLKLDCHESIIPRGEYYDNISFSHKACAWQGATLGNDYVRGRDYLKSGLKYTYHHVWRNFGIIIGFLCFFLFCSLLAAEYITPLFTRENLLRWNNYLKRYCPFLNSQKKNNKSAITNNDGVCTPKTPIANFSTSSSSVPSVSHQYDTDYNIKHPDETVNNHTKESVAMETQKHVISWKNINYTIGDKKLINDASGYISSGLTALMGESGAGKTTLLNVLSQRTESGVVTGELLIDGQPLTNIDAFRRSIGFVQQQDVHLELLTVRESLEISCVLRGDGDRDYLGVVSNLLRLPSEKLVADLSPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALTIVQFLKKLSMQGQAILCTIHQPSKSVISYFDNIYLLKRGGECVYFGSLPNACDYFVAHDRRLTFDREMDNPADFVIDVVGSGSTNIPMDDAEKPTSSKIDEPVSYHKQSDSINWAELWQSSPEKVRVADDLLLLEEEARKSGVDFTTSVWSPPSYMEQIKLITKRQYICTKRDMTYVFAKYALNAGAGLFIGFSFWRTKHNINGLQDAIFLCFMMLCVSSPLINQVQDKALQSKEVYIAREARSNTYHWTVLLIAQTIVELPLAISSSTLFFLCCYFCCGFETSARVAGVFYLNYILFSMYYLSFGLWLLYSAPDLQTAAVFVAFLYSFTASFCGVMQPYSLFPRFWTFMYRVSPYTYFIETFVSLLLHDREVNCSTSEMVPSQPVMGQTCGQFMKPFIDEFGGKLHINNTYTVCAYCMYTVGDDFLAQENMSYHHRWRNFGFEWVFVCFNIAAMFVGFYLTYIKKIWPSVIDGIKKCIPSMRRSKTSHNPNEQSV
Protein: Carboxypeptidase Q (EC 3.4.17.-) (Hematopoietic lineage switch 2 related protein) (Hls2-rp) (Liver annexin-like protein 1) (LAL-1) (Plasma glutamate carboxypeptidase) (Q6IRK9)
Organism: Rattus norvegicus (Rat)
Function: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:22127294}. Golgi apparatus {ECO:0000269|PubMed:22127294}. Lysosome {ECO:0000269|PubMed:22127294}. Secreted {ECO:0000269|PubMed:22127294}. Note=Secretion is stimulated by TSH/thyroid-stimulating hormone, INS/insulin and SST/somatostatin.
Interaction partners:
Sequence:
MRFLFFLFVAVVHLFSLGSGKAIYKSGVSQRTFQEIKEEIANYEDVAKAIINLAVYGKYQNRSYERLGLLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLENVHLEQVRIPHWERGEESAVMVVPRIHKLAILGLGGSIGTPPEGITAEVLVVASFVELQRRASEARGKIVVYNQPYTDYGKTVQYRERGAVEAAKVGAVASLIRSVASFSIYSPHTGHQGYQDGVPKIPTACITIEDAEMMSRMASRGDKIVIHLKMGAKTYPDTDSFNTVAEITGSKYPEEVVLVSGHLDSWDVGQGALDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTAEEQGGVGASQYYELHKANISKYSLVMEADSGTFLPTGLQFTGSDKARAIMKEVMSLLQPLNITKVFNDAEGTDINFWIQAGVPGASLRDDLYKYFFFHHSHGDTMTAMDPKQMNVAAAVWAVVAYVVADMEEMLPRS
Protein: Deoxyribonuclease-1-like 1 (EC 3.1.21.-) (DNase X) (Deoxyribonuclease I-like 1) (DNase I-like 1) (Muscle-specific DNase I-like) (XIB) (P49184)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16107205}.
Interaction partners:
Sequence:
MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDEDDVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLLHTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCPAA
Protein: L3MBTL histone methyl-lysine binding protein 3 (E9PLL7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATATTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEER
Protein: Early growth response protein (A0A0H2UHR3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU363046}.
Interaction partners:
Sequence:
MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAPQFLGAAGTPEGSGGNNSSSSSSSSSGGGGGGGSNSGSSAFNPQGEPSEQPYEHLTTESFSDIALNNEKALVETSYPSQTTRLPPITYTGRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPTSSSSAPSPAASSSSSASQSPPLSCAVPSNDSSPIYSAAPTFPTPNTDIFPEPQSQAFPGSAGTALQYPPPAYPATKGGFQVPMIPDYLFPQQQGDLSLGTPDQKPFQGLENRTQQPSLTPLSTIKAFATQSGSQDLKALNNTYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKSVVASSAASSLSSYPSPVATSYPSPATTSFPSPVPTSYSSPGSSTYPSPAHSGFPSPSVATTYASVPPAFPAQVSTFQSAGVSNSFSTSTGLSDMTATFSPRTIEIC
Protein: LD21810p (Q9VJ64)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- DCN1-like protein 3
Sequence:
MSLEDLKIKLRRHPKLLGLGGVGLITAAGFLLYESPQVRRFLSQYVDKKSPEPDKRRAEYIYIKYHIYRESMRKLKQKEEDEKKWISVIINPIGKWWKAAKHSVAWRLLNIAQTGSQPERLKAVQQLICMDHLKDWDFRHLAQICDARTAVSLARCNADTRWFMPVPRRGCIKNPKMLLSELHVMLARLRPMACIDHFFSKYFPEQDPIEDIHEYLTQEQTIVLSTADTDLLKEIISFLHHITKDPEVSARLMRDGGLVHLMELRKIFNDDNETLSTLCKVLANMSLVPDAVEHFFTSGWVGALAEWQQCPDLRLQVISAKTMANLDHDDPNQCTYPPNVYPLHPRVRTRRKPKADIVFVHGLLGGVFITWRQRDRKPTELGLYGKNAFYTSETDDVFLVGEQKRLSGGKLKPGEAVKNVNGNQKTETIKDPVLKASKKVEEQRLNISDAATKEFVETLRNEAELDSDWEVVHPDVPLNANEECEGKFSVCGSEWRNQDTSEEYTNCWPMEWLPDDYPDSRILGIDYTSAVTEWSANFTKYCPCEKGQGHIDVRANTLLDRISASDVGNDRPIVWIGHSMGGLLTKLILLKSLDSQEPKVQQLTKNTKGIVFLGTPHRGSPIAKWKQHMQMILSPSIEVKEMEENSPKLLEMHRRFMGCLHTLLRHVKVVSVAEGSPTMLTSFKFPLRIVTEESSKIDFGDFYLLKDDHLSLSKPIYRQSFLYQRLLHVIREAIKERSDPKDQDGQSQSTSNQDVVLVKIVAALLEGAKGLFESLPRVALRFST
Protein: Transmembrane protein 11, mitochondrial (Protein PM1) (Protein PMI) (P17152)
Organism: Homo sapiens (Human)
Function: Plays a role in mitochondrial morphogenesis.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:21274005}; Multi-pass membrane protein {ECO:0000269|PubMed:21274005}.
Interaction partners:
- DnaJ homolog subfamily C member 11
- Stress-70 protein, mitochondrial
- MICOS complex subunit MIC27
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
- Ras-related GTP-binding protein A
- Metaxin-2
- MICOS complex subunit MIC10
- MICOS complex subunit MIC60
- MICOS complex subunit MIC13
- MICOS complex subunit MIC19
Sequence:
MAAWGRRRLGPGSSGGSARERVSLSATDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTACLFTPLALPLDYSHYISLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV
Protein: Tubulin glycylase 3E (EC 6.3.2.-) (Q23AS2)
Organism: Tetrahymena thermophila (strain SB210)
Function: Probable glycylase which modifies tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of tubulin.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:19531357}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:19531357}. Note=Mainly present in locomotory and oral cilia.
Interaction partners:
Sequence:
MILPFEYYFLNDADNSSKSNYNNIQFINENQNNNLRQKPKFYPNNQFLIEQEQDKYENKKIKNYISDQIQLQPKNTPINKMNHFANINNYQDNKFSLESLNQAQQDNLQKEEDLSILSFDSQEELNYLQEGEENNQFLNEGDIFGYQTRYTFFENRNNLLVEDATNKNNNNYNYNYNNNNSSTQRNYDFNYQNTNEMLQKKKKSNFQNKSQSQLNNHKNEEKKPSQQRKEQLMKRFESLSRIYNKELSQTVTNGWLKPSQAKTISQDNNLGSSAAKSSKVFYQQQKPFSAQITNSSLKYAAASNGFQNLDFSYKQKQQLIQQETKNKIKEQQNVESNNRISMKPPKSANLNSYKNISNLKNFKEIILTRPNSKQVKFQQQNSVNSQPSSLVSQPLKIQSIEKNNLNSNLNDQNFYDDFAELGSTETTGFSFQNVFQLAGVPKDFIASPRSPVQELNQKQENRENELDQMLNDHHIYVASSVTNQNQIKNEQTERKPNMFGKTLTTLARPFSKEYSNRKDILKSAQQNVRFNKNLDYLDSQNKVVAKNKKRTIFKINQNNLQGNQKDLQSNQTSSVISQQNSIQQYGDDNYQQNQVLNDDQSPLIKQNSIDLNAAEIIQNDENENTQKENVLQQKKNQSNQIVTSQQQSNNYFKQETTTNTSNFSTTSNRIISLQALRQKNNSTVKNSDNNNQNQTNPQNQNTNLKENNDKQNLKKTKIQSASANQAGQSNNQLQKTFFINSQDEYVRRTLLRMGWKENKLLLNNNFDLKWIYIDSNDDYKFLNDNQFYNHFKNNTELTQKGRLLYNLKNNTQFGVNQELFFPRCYDLGNDQERGEFSNEFNRMNVMNLLKKHIQYIKLRRSQTYQEIKQAYQQKQANKLNAQVKDGIFFAKVTKQKFFSPLMYEDTKRDNRFIFNITVIAEAVEILKKLKRQQEEYIDETRQSRDCQLYIYQTNFKLESMISQYVKINVPFDEEKFVFEKIVGMSKEHWSSPSMKLMKKLYSLYKYFKDADPQFKVSGTKNIWIIKPSANSRGSGIYLVDKLDEAIDSGLKMQARIVQKYIERPLIFQGAKYKKLNNKKFDIRQWVLVTSFKPLKIYFFTSSYLRVCSQSFDLDNIKILSKHLTNFSLNKNSLAKENWDETVVELKDFISYLKEFKNIDYQEDVKPKIKDLVIETIKCAADKIVNRKKSFELYGFDILLDEYAHPWLLEVNLSPACSERSSFLTEMLDAMAYKMFQIVFKQNNLQEDLEINKETAISTAPASCQNPDYDWEEIYNEEQKEYFCEEDNNMQLAFNNDIQLMVIGQKADLKKEKNLDKKYFQYWGAIKIQSKIRSFLAKKKLQRLKNQKFTFAAIKIQQKMRQFLAKKQLNILKKQQQTNINIPIEDFNQVSVIEV
Protein: Uncharacterized protein (Q388Y4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cytoplasmic dynein 2 light intermediate chain 1
- Cytoplasmic dynein 2 heavy chain 1
- Intraflagellar transport protein IFT88, putative
- Dynein heavy chain, putative
- C2H2-type domain-containing protein
- Intraflagellar transport protein A1
- Uncharacterized protein
- Intraflagellar transport protein 57/55
- Intraflagellar transport protein 80
- Intraflagellar transport protein component, putative
Sequence:
MGDDTTTKSKRDETEEERRARKEKERAERKAKEKEEKKEKEEKEVGNDGEKERKSKRDETEEERRARKEKERAERKAKEKEEKKEKEEKEVGNDGEKERKSKRDETEEERRARKEKERAERKAKEKEEKKEKEEKEVGNDGEKERKSKRDETEEERRARKEKERAERKAKEKEEKKEKEEKEVGNDGEKERKSKRDETEEERRARKEKERAERKAKEKEEKKEKGKKEMEKEKEETIDEDGDDLQDILSNKKGAKQASPRNEQGVSPESRRGRTTALVAGQKTEELAAAMAAENHAIRQAAHEAKEAAQQNERRRAEEEREREALERRELRRKEREEKRNKRGNDSKATTGPLGTSAFAAEDLQRQGYVTQFDKDLQRATALRRLVDMDDVAAALVDAPPQSQYDMYIRSFGESGRKQVGVQNPAEEDRTDVGVQAERVRVKSRGVEVPRDLGLCPELHTNNVAQFTTGKGGTDGGTVTENTQQQQFADGALLAGFLNRVFPIIRAAMDENEGVGSDATKAKSETQFSSSCVSFCFSAARNRPVLKVLFNPCNPTYIVALHGSCVEEGPSKEMDRYMSVILLWSIYDNTAPEKVLVSPSVITCISASPRKPYLIYGGSEDGSVFLWDTREPERNHTTAGRYEGHRFRLPSFSTSWQAGNHLAPLVSVTVAGYNTATGIRKDEAEQLVSLDAFGETHFWVVNEKDQAKGAIIDNENGLNMFSTVRLLLAASKGSDRANSASLSQEAFAIDFVPSDPSHYVVACAEGVRHISRFGSVAAPSVYGPSSRFFNQPIVVPSCVQYNPVDNRILMVGYDDGSVRVYLHTEGSPQISIPLSTHRVTEIRCSLMDKWLYWVLDAGGMFYLLDLAKGERELPVFSQSLSQTNAGICTCFDTPPEAKAESRMVVFGFEKGEVQLHTLNDLTHSLNPDRNELWL
Protein: HIG1 domain-containing protein (Q59QA9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Cytochrome c oxidase subunit
- Cytochrome c oxidase subunit
- Cytochrome b-c1 complex reductase subunit, mitochondrial
- Cytochrome c oxidase subunit 4, mitochondrial
- Cytochrome c oxidase subunit 1
- Cytochrome b-c1 complex subunit 8, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase subunit 3
- Cytochrome b-c1 complex catalytic subunit, mitochondrial
Sequence:
MKILSKEEKDAHISHIISEGAKGLFYGGALSVGLYQYLKHRHPARFATFNPSIKAAIIAMPTISVAAFFADQGSVEFDRKMHQSEYQEAKYLEEYREWNRLSLSDKCFTVLNDNKYKIIISAWAGSLYGSWVLVNRDKIMDTAQKAVQARMYAQGITIILLLGTLLLAMKEEEINKKKPKPIPEWKRIIMEKEAEDKRLVDEANKVAQEKATQ
Protein: SP-RING-type domain-containing protein (Q586P7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Small ubiquitin protein, putative
- SUMO-conjugating enzyme UBC9
Sequence:
MLPPISVQSPCFPILSLVRRFDLSSSGGSDGIVLQKVGVPPSSARNVASFSDRVDLVLFPCKLGDPAQPIGWPQTNQQEFTVMVNDRFITSEFPRCPSRSASHRTLAGMPLSSFLPKGPDGGIAAEAELKILVVRRGKWTATFLLAWCNVIEPEVIIDRTIARLLREPLSTPAKANEWDSASSSASAAESAAGDSDIDVDSGWVDDKADNTHNSGGRNGRKSADAPNLPNGTAGDNGVQDGEAVVTLRCPLSYGRMKIAGRGNHCSHLTCFDLLTYLSASLQSNSWNCPICDGPVFIGDVCIDSTLQAALEGLDSNAFSVVLFGRDHKEWRSVEGATCGSDEESVDGCEVMMVEEEEEEINQQEKQQSECPSLPLTT
Protein: Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) (F1QMH7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004135}. Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}. Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Interaction partners:
- Agrin
- Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
- Heparan sulfate proteoglycan 2.
- Protein O-mannosyl-transferase 1
- Protein O-mannosyl-transferase 2
- Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase
- Dystrophin
- Gamma-sarcoglycan
- UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
- Protein O-mannose kinase
Sequence:
MRNKLREFRDGGRPMLGQWDRTLVVLLMALALTVTDVRASWDQMEVLGDVKLEASMHSAVLSDIREAEAVVAAVSQPSGFPDSSAVVGRVFRLQVPIKAKDSGSIVKITEASKDVLPAWLHWDAESGTLQGLPLETDKGVHYISVSVSNESKVSQSPDVFSIEVHPEEHAETDPFQLAIQQSASNDAQPFICGNEEPVTVLTVILDADLTKMSSKQRVELLAKMKKFSGMGLQHMKILPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCSLDQSSIPDISSVQVPAKEGTMSAQLGYPVVGWHIANKKPHVPKRVRRQLNNTPTPIPSLLPPTTYPEPPIRIVPTPTSPSIAPTSESSAPPVRGPVPLPVKPTIRNRDSAPSTPTLGPPLPTRVMVTTSTIAIQPTMTRPVYVGASVTPATPTTRKPTKRPPKKPKTTPIPREPKTTTTKPPRRSTPAVIGDSNIKPELRNPIDQVNAYVGTYFEVKVPSDTFFDKEDGTTDKLRLTLRKGNDVVADDSWIQFNSTSQLLYGLPDQEHAGKHEYFMQATDKGGLYAMDAFEVRVSMWGNSVKPPVLFTAVFDGDARTVTNDIHKKILLVKKLSQSFGDRNSSTITLKSITKGSIIVEWTNNSLQQSPCPKDQIQQLSKKISDPEGKPSSIFKFTMEPDFRPSNITVRGTASCRNYMFVPLGEIPDPTPSPGTPAVGAGRQSTDDVYLHTVIPAVVVAAILLIAGIIAMICYRKKRKGKLTIEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILQEEKPPLPPPEYPNMATPETTPLNQDLLGEYTPLHDEDPNAPPYQPPPPFSTPMEGKGSRPKNMTPYRSPPPYVPP
Protein: Tumor necrosis factor receptor superfamily member 4 (OX40 antigen) (OX40L receptor) (CD antigen CD134) (P47741)
Organism: Mus musculus (Mouse)
Function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Tumor necrosis factor ligand superfamily member 4
- Tumor necrosis factor ligand superfamily member 9
- T-lymphocyte activation antigen CD80
- CD70 antigen
- T-lymphocyte activation antigen CD86
- ICOS ligand
- Tumor necrosis factor receptor superfamily member 9
- Inducible T-cell costimulator
- Tumor necrosis factor receptor superfamily member 5
- CD40 ligand
Sequence:
MYVWVQQPTALLLLALTLGVTARRLNCVKHTYPSGHKCCRECQPGHGMVSRCDHTRDTLCHPCETGFYNEAVNYDTCKQCTQCNHRSGSELKQNCTPTQDTVCRCRPGTQPRQDSGYKLGVDCVPCPPGHFSPGNNQACKPWTNCTLSGKQTRHPASDSLDAVCEDRSLLATLLWETQRPTFRPTTVQSTTVWPRTSELPSPPTLVTPEGPAFAVLLGLGLGLLAPLTVLLALYLLRKAWRLPNTPKPCWGNSFRTPIQEEHTDAHFTLAKI
Protein: Protein Notchless (Q9VPR4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in regulating Notch activity.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Nucleolar GTP-binding protein 1
- Ribosome biogenesis protein NOP53
- Protein SDA1 homolog
- Nucleolar GTP-binding protein 2
- Guanine nucleotide-binding protein-like 3 homolog
- FI20216p1
- Ribosome biogenesis protein NSA2 homolog
- Ribosome assembly factor mrt4
- Uncharacterized protein, isoform A
- Ribosome production factor 2 homolog
Sequence:
MLAKKQKMQETDTEQEATPHTIQARLVSDTGEEAGPPIDLPAGITTQQLGLICNALLKNEEATPYLFFVGEDEIKKSLEDTLDLASVDTENVIDIVYQPQAVFKVRPVTRCTSSMPGHAEAVVSLNFSPDGAHLASGSGDTTVRLWDLNTETPHFTCTGHKQWVLCVSWAPDGKRLASGCKAGSIIIWDPETGQQKGRPLSGHKKHINCLAWEPYHRDPECRKLASASGDGDCRIWDVKLGQCLMNIAGHTNAVTAVRWGGAGLIYTSSKDRTVKMWRAADGILCRTFSGHAHWVNNIALSTDYVLRTGPFHPVKDRSKSHLSLSTEELQESALKRYQAVCPDEVESLVSCSDDNTLYLWRNNQNKCVERMTGHQNVVNDVKYSPDVKLIASASFDKSVRLWRASDGQYMATFRGHVQAVYTVAWSADSRLIVSGSKDSTLKVWSVQTKKLAQELPGHADEVFGVDWAPDGSRVASGGKDKVIKLWAY
Protein: GTP-binding protein RHO1 (O42825)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Rga2p
- Protein kinase C-like 1
- Rho family guanine nucleotide exchange factor
- Lrg1p
- Sac7p
- Formin BNI1
- Rho family guanine nucleotide exchange factor
- Formin BNR1
- Bem2p
- Mitogen-activated protein kinase kinase kinase
Sequence:
MVNGPAELRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGRKVELALWDTAGQEDYDRLRPLSYPDSNVILICFSVDSPDSLDNVLEKWISEVLHFCQGVPIILVGCKSDLRDDPHTIEALRQQQQQPVSTSEGQQVAQRIGAADYLECSAKTGRGVREVFEAATRASLRVKEKKEKKKKCVVL