wanglab/gogpt-training-data huggingface dataset:
Protein: Myeloid differentiation primary response protein MyD88 (Q4LBC6)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MSASLDLWNIPLRALNINVRKRLGLFLNPRNTVASDWMSVAENMGFSYLEIKNYEDCQDPTRKIYRTGKPLSRAQVGKLVSILDNVTRKDVVEDLRVLIEEDCKRYIERQNEPPVQVPEVDSCVPRTPERQGITLEDDPEGGIPELFDAFICYCQSDFDFVHEMIQQLEQTDHKLKLCVFDRDALPGSCVWTITSELIEKRCKRMVVVISDEYLDSDACDFQTKFALSLCPGARSKRLIPVKYKSMKKPFPSILRFLTVCDYPRPCTQSWFWVRLAKALSLP
Protein: Small ribosomal subunit protein uS8m (37S ribosomal protein S8, mitochondrial) (Q03799)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein uS17m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS7m
Sequence:
MSLVKLANTCAHLQNCSKVRVALTSIPYTKLQLQFAYNLYQQGFLSSLQKGSTMGPDKDFVEVTPDNISTRRLWVGLKYRDNKPVLSSCKLISKPNSRIHLPMEDMKKLCSGVTIRNIKPLQPGELILVRAHNNIMDINEAISKKLDGEVLCRVK
Protein: Bifunctional uridylyltransferase/uridylyl-removing enzyme (UTase/UR) (Bifunctional [protein-PII] modification enzyme) (Bifunctional nitrogen sensor protein) [Includes: [Protein-PII] uridylyltransferase (PII uridylyltransferase) (UTase) (EC 2.7.7.59); [Protein-PII]-UMP uridylyl-removing enzyme (UR) (EC 3.1.4.-)] (Q8VS59)
Organism: Gluconacetobacter diazotrophicus (Acetobacter diazotrophicus)
Interaction partners:
Sequence:
MEGRPPSGPTPMQEIDPPAMSTPSSPSQASTPSAVRDLTTSLAASLLSPEDGAAVPREQAIALFRRHLARFQASVREEFEAHRLHGTSAAKQLALHTDGMIRTLVDFTLDHALAGSIGPGARSLAVTATGGYGRGMLAPFSDIDLLFLTTDEPSADVSRVVEYILYFLWDLGLKVGHATRSIAQCIAEAEADTNRPHHIAGRPAAGPATRRCSPCSRPGYIVACVEAGAARFISDKHKERTARHNRFGDSPYLVEPNVKEGRGGLRDLQTLYWMCRYTFGTRHVSDLLAPGFSRLGLLTEQEAKRARRSWDFLWSVRLHLHYISGRAEERLTFDVQPVVGARMGYTRHGRQVGVERFMRHYFLTVREVMRLTHVLEPAVMRQALGPAANAPQADSAMRDAGFTVLDGQILPERGTSFDAEPIQMMRLLEWARTRKLPIHPLAMHQLIRWERRAASLRGDPEAARIFLELLCGTPPERIGRPPHSAEAENAAGEEVPSFHATAQDRRQGNAYWLHILNETGIMGRLMPDWSRIVGQMQFDTYHVFTVDEHTIEAIRIFGRIEHGAMADEIPQAYDLARNLQSRRALYMAILLHDIAKGRGGDHSELGSEIALDVCPEMGLTGEETETVSWLVLHHLLLSHTAFQRDIDDPKTILDLADTIQSPEALRLLLLLTIVDMRAVSPRVWNAWKATLLHELYMRVAEVLEGGLATTERDVRVARAKDAAAEILEDDGFKRADIDHFLGLGYGSYWLSFDQDTHARHAELIREAERHKAPLTVETQPLPARGVTEVTIYTADHPGLFSRMAGALAIAGASIVDARIHTLINGMALDTFWIQDAGGEAFEEPHQLARLSALVEQALSGRVDIPKEIVSAGRMRYGRRMRAIHVPPRVVIDNRASNTYTVIEINGRDRPGLLHDVTQAISDHKLQIASAHITTYGVRAVDVFYVKDLFGLKITDERRLGEIREALLHGLRQAEEAMTSEIGPPAESLIA
Protein: 1-aminocyclopropane-1-carboxylate synthase 2 (ACC synthase 2) (OsACS2) (EC 4.4.1.14) (Q7XQ85)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants (Probable). Involved in defense response by producing ethylene after pathogen infection. Involved in several phospate deficiency-induced adaptive responses, such as lateral root elongation.
Interaction partners:
- Mitogen-activated protein kinase 5
- Mitogen-activated protein kinase 1
- S-adenosylmethionine synthase 3
- S-adenosylmethionine decarboxylase proenzyme
- Aminopropyl transferase
- Spermidine synthase 1
- Os06g0112200 protein
- Os06g0573900 protein
- S-adenosylmethionine decarboxylase proenzyme
- 1-aminocyclopropane-1-carboxylate oxidase 1
Sequence:
MAYQGIDLLSTKAAGDDHGENSSYFDGWKAYDTNPFDLRHNRGGVIQMGLAENQLSLDLIEEWSKNHPEASICTPEGVSQFKRIANFQDYHGLPEFRKAMAQFMGQVRGGKATFDPDRVVMSGGATGAQETLAFCLANPGEAFLVPTPYYPAFDRDCCWRSGIKLLPIECHSFNDFRLTKEALVSAYDGARRQGISVKGILITNPSNPLGTITDRDTLAMLATFATEHRVHLVCDEIYAGSVFATPEYVSIAEVIERDVPWCNRDLIHVVYSLSKDFGLPGFRVGIIYSYNDAVVAAARRMSSFGLVSSQTQYFLARMLSDEEFIGRFLQESKCRLVARHERFTSGLREVGIGCLRGNAGLFSWMDLRRMLREKTAEAELELWRVIVHQVKLNVSPGTSFHCREPGWFRVCHANMDDETMEVALGRIHDFVRQHQQRRVKAERWAANRQLRLSLPHHHHLSPAHLSSPLALLSPQSPMVRATS
Protein: Cytochrome b6-f complex iron-sulfur subunit, chloroplastic (EC 7.1.1.6) (Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein) (Proton gradient regulation protein 1) (Rieske iron-sulfur protein) (ISP) (RISP) (Q9ZR03)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protein for photoautotrophism. Confers resistance to photo-oxidative damages by contributing to the thermal dissipation of light energy and to lumenal acidification (increase of pH gradient). Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity).
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000255}. Mitochondrion inner membrane {ECO:0000269|PubMed:31118221}; Single-pass membrane protein {ECO:0000255}. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer. {ECO:0000250}.
Interaction partners:
- Cytochrome b6
- Cytochrome f
- Cytochrome b6-f complex subunit 4
- Cytochrome b-c1 complex subunit 9, mitochondrial
- Cytochrome b6-f complex subunit 5
- Cytochrome c1 2, heme protein, mitochondrial
- Cytochrome c1 1, heme protein, mitochondrial
- Cytochrome b-c1 complex subunit 7-1, mitochondrial
- Cytochrome b-c1 complex subunit 7-2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
Sequence:
MASSSLSPATQLGSSRSALMAMSSGLFVKPTKMNHQMVRKEKIGLRISCQASSIPADRVPDMEKRKTLNLLLLGALSLPTGYMLVPYATFFVPPGTGGGGGGTPAKDALGNDVVAAEWLKTHGPGDRTLTQGLKGDPTYLVVENDKTLATYGINAVCTHLGCVVPWNKAENKFLCPCHGSQYNAQGRVVRGPAPLSLALAHADIDEAGKVLFVPWVETDFRTGDAPWWS
Protein: Pheromone-binding protein Gp-9 (PBP) (Putative odorant-binding protein Gp-9) (Q8WP90)
Organism: Solenopsis invicta (Red imported fire ant) (Solenopsis wagneri)
Function: Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9. Colonies are headed by either a single reproductive queen (monogyne form) or multiple queens (polygyne form). Differences in worker Gp-9 genotypes between social forms may cause differences in workers' abilities to recognize queens and regulate their numbers.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MKTFVLHIFIFALVAFASASRDSARKIGSQYDNYATCLAEHSLTEDDIFSIGEVSSGQHKTNHEDTELHKNGCVMQCLLEKDGLMSGADYDEEKMREDYIKETGAQPGDQRIEALNACMQETKDMEDKCDKSLLLVACVLAAEAVLADSNEGA
Protein: Copine 3 (A0A087WUS8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKGSITISAEEI
Protein: ATP-dependent zinc metalloprotease YME1 homolog (EC 3.4.24.-) (O59824)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Putative ATP-dependent protease.
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:16823372}; Single-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Mitochondrial escape protein 2
- Lon protease homolog, mitochondrial
- Prohibitin-2
- Prohibitin-1
- Mitochondrial metalloendopeptidase OMA1
- Mitochondrial import inner membrane translocase subunit tim54
- TPR repeat-containing protein P27G11.02
- Mitochondrial import inner membrane translocase subunit tim9
Sequence:
MSRVLHPIFLFGKTSFLYSGCSKFGGRLFNNSIVHGWLRTRSYALASGLHPLRKQKLAHFEDLANANMSDPYMQAKLYKELADNFPEAIISRYETQGVARNSACDRYYQEALRKKSWSRSLSNNISLSQSSSSPATSSFSDPKAFSAGVPKFTSDTSSTVSSTPSLNHSLQNSMPPSTPTPPPVWAPTIVSSALGTSSKTPVYVVVDEPRFTKFFRIFKFIAGLSVASYFVLLGMSIFAETSGLNNIMTNTTEQEPMEERAINVRFSDVQGVDEAKEELEEIVDFLRDPTHFTRLGGKLPRGVLLTGPPGTGKTMLARAVAGEANVPFFFMSGSQFDEMYVGVGAKRVRELFAAARKQAPSIIFIDELDAIGQKRNARDAAHMRQTLNQLLVDLDGFSKNEDLAHPVVFIGATNFPESLDPALTRPGRFDRHIHVPLPDVRGRLAILLQHTRHVPLGKDVDLSIIARGTSGFAGADLANLINQAAVYASKNLSTAVSMRDLEWSKDRILMGAERKSAFITPENKLMTAYHEGGHALVALFTKNAMRPYKATIMPRGSSLGMTISLPDMDKDSWTREEYLAMLDVTMGGRAAEELLYGKDKITSGAHNDIDKATQVARRMVTEFGMSDRIGPVSLEAEMDNLSPATRALVESEIKSLLEASYERSLSLLKSHKKELDALATALVDYEFLTAEEMNRVVKGDRDLLRNKLS
Protein: Asparagine synthetase [glutamine-hydrolyzing] 1 (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase 1) (Protein DARK INDUCIBLE 6) (P49078)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential for nitrogen assimilation, distribution and remobilization within the plant via the phloem.
Interaction partners:
- Aspartate aminotransferase 3, chloroplastic
- Probable isoaspartyl peptidase/L-asparaginase 2
- Isoaspartyl peptidase/L-asparaginase 1
- Aspartate aminotransferase, cytoplasmic isozyme 1
- Aspartate aminotransferase, mitochondrial
- Adenylosuccinate synthetase, chloroplastic
- Aspartate aminotransferase, chloroplastic
- Aspartate aminotransferase, cytoplasmic isozyme 2
- Aspartokinase 3, chloroplastic
- Aspartokinase 2, chloroplastic
Sequence:
MCGILAVLGCSDDSQAKRVRVLELSRRLRHRGPDWSGLYQNGDNYLAHQRLAVIDPASGDQPLFNEDKTIVVTVNGEIYNHEELRKRLKNHKFRTGSDCEVIAHLYEEYGVDFVDMLDGIFSFVLLDTRDNSFMVARDAIGVTSLYIGWGLDGSVWISSEMKGLNDDCEHFETFPPGHFYSSKLGGFKQWYNPPWFNESVPSTPYEPLAIRRAFENAVIKRLMTDVPFGVLLSGGLDSSLVASITARHLAGTKAAKQWGPQLHSFCVGLEGSPDLKAGKEVAEYLGTVHHEFHFSVQDGIDAIEDVIYHVETYDVTTIRASTPMFLMSRKIKSLGVKMVLSGEGADEIFGGYLYFHKAPNKKEFHQETCRKIKALHKYDCLRANKSTSAFGLEARVPFLDKDFINTAMSLDPESKMIKPEEGRIEKWVLRRAFDDEERPYLPKHILYRQKEQFSDGVGYSWIDGLKDHAAQNVNDKMMSNAGHIFPHNTPNTKEAYYYRMIFERFFPQNSARLTVPGGATVACSTAKAVEWDASWSNNMDPSGRAAIGVHLSAYDGKNVALTIPPLKAIDNMPMMMGQGVVIQS
Protein: Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA) (P23708)
Organism: Mus musculus (Mouse)
Function: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component BMAL1.
Subcellular location: Nucleus.
Interaction partners:
- Nuclear transcription factor Y subunit gamma
- Nuclear transcription factor Y subunit beta
- TATA-box-binding protein
- MHC class II transactivator
- TATA box-binding protein-like 1
- TATA box-binding protein-like 2
- CCAAT/enhancer-binding protein zeta
- Chromatin accessibility complex protein 1
- Speedy protein A
- Cyclic AMP-dependent transcription factor ATF-2
Sequence:
MEQYTTNSNSSTEQIVVQAGQIQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS
Protein: AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin) (P53680)
Organism: Homo sapiens (Human)
Function: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif (By similarity). May also play a role in extracellular calcium homeostasis.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P63010}. Membrane, coated pit {ECO:0000269|PubMed:33859415}; Peripheral membrane protein {ECO:0000305|PubMed:33859415}; Cytoplasmic side {ECO:0000305|PubMed:33859415}. Note=AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV. {ECO:0000250|UniProtKB:P63010}.
Interaction partners:
- AP-2 complex subunit beta
- AP-2 complex subunit mu
- AP-2 complex subunit alpha-1
- AP-2 complex subunit alpha-2
- AP-4 complex subunit beta-1
- AP-1 complex subunit beta-1
- Clathrin light chain A
- Clathrin light chain B
- AP-4 complex subunit epsilon-1
- Clathrin heavy chain 1
Sequence:
MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE
Protein: Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7) (Keratin-37) (K37) (O76014)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGSTPLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCTSCPSCGPVTGGSPSGHGASMGR
Protein: Bet1-like protein At1g29060 (Q8L9S0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE associated with ER-derived vesicles (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Interaction partners:
- VAMP-like protein YKT62
- Golgi SNAP receptor complex member 1-1
- Golgi SNAP receptor complex member 1-2
- Syntaxin-31
- VAMP-like protein YKT61
- Syntaxin-32
- Bet1-like protein At4g14600
- Protein YIP
- AAA-ATPase At5g17760
- Protein OXIDATIVE STRESS 3 LIKE 4
Sequence:
MASNRGAGGSLYGGADPYRSREGLSTRNASGSEEIQLRIDPMHSDLDDEILGLHGQVRQLKNIAQEIGSEAKSQRDFLDELQMTLIRAQAGVKNNIRKLNLSIIRSGNNHIMHVVLFALLLFFILYMWSKMFKR
Protein: Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6) (A0A087WYL7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR023869}.
Interaction partners:
Sequence:
MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPEKRMRLHYIILSIKINSC
Protein: Matrilin 1 (E1BMV3)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Annexin A10
Sequence:
MRALSGPRLMLCGLLLLLFQAPCALGLAPLSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGLVNYASSVKQEFPLRAHSSKAELLQAVRRIQPLSTGTMTGLAIQFAITKALSDAEGGRPRSPDISKVVIVVTDGRPQDSVRDVSARARAGGIELFAIGVGRVDKATLQQIASEPQDEHVDYVESYSVIEKLSKKFQEAFCLVSDLCATGDHDCEQVCVSSPGSYTCACREGFTLNSDGKTCNVCNGGGGSSATDLVFLIDGSKSVRPENFELVKKFINQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKRICVEEDPCACESIVKFQTKVEGLLQALTRKHILSQKPLRGEGAVRRALWWRGGESLAPCVVGSGRLLLKTGWILAREAGLGFGTEKGEAETKS
Protein: Arginine attenuator peptide (AAP) (Arg-2 leader peptide) (P22702)
Organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function: Arginine attenuator peptide (AAP) that has a regulatory role in the production of arginine-specific carbamoyl phosphate synthetase. Encoded by an upstream open reading frame (uORF) within the 5'-leader region of arginine-specific carbamoyl phosphate synthetase small chain (arg-2) mRNA, it attenuates the translation of the downstream arg-2 ORF. In the presence of high concentrations of arginine, ribosomes translating the uORF encoding AAP stall at the termination codon, resulting in reduced translation from the downstream arg-2 initiation codon.
Interaction partners:
- Carbamoyl phosphate synthase arginine-specific small chain
Sequence:
MNGRPSVFTSQDYLSDHLWRALNA
Protein: IK cytokine (Protein Red) (Q860B9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- WD40 repeat-containing protein SMU1
- WD40 repeat-containing protein SMU1
- Pre-mRNA-processing factor 6
- WD repeat-containing protein 55
- Microfibril-associated protein 1.
- Elongation factor Tu GTP-binding domain-containing 2.
- Splicing factor 3B subunit 3
- Pre-mRNA-splicing factor 38A
- U6 snRNA-associated Sm-like protein LSm4
- U5 small nuclear ribonucleoprotein 40 kDa protein
Sequence:
MPERETDVYSNPLAPDGHEVEDHRSALQSKLTNDDFRKLLMTPRATPSSAPPSKTRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEMERERELAEKYRDRARERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEITSKEREEEDMIEKVQKEVKKDEDPEQKIEFKTRMGRNIYRNVFKGRQLERNELFLPGRMAYVVDLEDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGRLDEKKAPEADLSIFDDIGDYIPSTSKGFRDKEKERYREREREKDRERERERERERERDRDEEKRRHSYFEKPRADEEVIDIDDKGPGSVKDQIKLINEKFAGAAHQLGPEAGSRRDEKKHLGDFFGMSNSYAECYPATMDDLAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSDYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNEKAELDRQWKKISAIIEKRKKMEADGVDIKRPKY
Protein: Uncharacterized protein (Q383M4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMDAQTSSLRIDVSDCVPVSEYSTGSPDSVGWSPHNILHVATQFAVFLHANELTAADAIIRPVYLPRADDASPMCISGAKWALGLTSDNMYPSTCRLCVLTTRDLFIYRVVRYGNGRVRTSAALCIIPSQRPAQTQIGETSPDFKKSVKRRGRDGLELLLRGDIDEDCGSDDGGGEPVRRWGNKTFDVIGECIIGYEWFPRDLLVVVTFRSIYIVDEPNKANSVDEGKESQQQTEYLPPPSYRFTGNPEASLRPSCAARVVGANAESMRLVVASPLFLRVFSISVEGGVNLLCCVQIPLLGGVPASLCCVQASEERPDIRVLVSVPLRVIHGNIIMSGAVGEPHNRGEGFRGGSCVAATAEQTAEWQLVNVWGCESGFGDDITVSRFVTISLGSFALRGSDFTTPSSVAGGGPFVVLGVCRRRLVGFFGKSCINLIQCSRMDCFVPPDEEGTELTGLAFHPSCTLAVVALQTASRRHPPFQLFPCPVERSGGFLERLLYFQEGFASVFDVEQSQARGVHGPALAGRVSALNNLQCRQTSTSYFMWEKLLPRSALSGNFLQGDGLRQYGSCRLPLISCPALLDSSDTSPGLLAALRMTYLNLRCEYGIELFLRFPETNALWRQTLIRLQRLSVDSYVITELILANAIQLLADKVSYSGFRRDGFQKYALPNDEYSLSLAYAAALQFIRLYHQMCEEKEADEMWSHSGEFKKQLNKFMACLEREGGGNGISNKGQPEPDPRFPCSVCGEVEKNRLSLSLFSRNQNVPKEGEQTTSDCSEGHHITAFSGRNFATLCFLSQDEVLSQCHACSVFDYAVGPYCGVCEGLMA
Protein: CG9617 protein (CG9617-PA) (FI02883p) (Suppressor-of-G2-allele-of-skp1) (Q9VHT3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cysteine and histidine-rich domain-containing protein morgana
- Heat shock protein 83
- Protein phosphatase PHLPP-like protein
- Heat shock protein 83
- LD23779p
- Heat shock protein 75 kDa, mitochondrial
- Cytosolic Prostaglandin E synthase
- Hsp90 co-chaperone Cdc37
Sequence:
MSVRHDWYQSETKVVITVLLKNAVDKNYAVEITQKRVHMTADGYELDLKLLHPIVVERSSYKAFSTKVEITLAKETGIRWENLEEAIVAAPVKPKAKNWDQLVSEEEKIDEKEAKGEAALTNLFKKIYSSSSPEVQKAMNKSFSESGGTVLSTNWNEVGKERVTVKPPNGTEFREWEK
Protein: Mitogen-activated protein kinase p38b (MAP kinase p38b) (MAPK p38b) (EC 2.7.11.24) (O61443)
Organism: Drosophila melanogaster (Fruit fly)
Function: Kinase involved in dpp signal transduction pathway in the process of wing morphogenesis when the levels of dpp are enhanced or inhibited. May down-regulate insect immunity gene expression after prolonged infection.
Subcellular location: Nucleus.
Interaction partners:
- mitogen-activated protein kinase kinase
- Activating transcription factor-2
- MAP kinase-activated protein kinase 2
- Mitogen-activated protein kinase p38a
- Forkhead box protein O
- Putative mitogen-activated protein kinase 14C
- Myocyte-specific enhancer factor 2
- Dual specificity mitogen-activated protein kinase kinase dSOR1
- protein-tyrosine-phosphatase
- Tyrosine-protein kinase Src64B
Sequence:
MSRKMAKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSFEENELPVEKWREMVFSEVTAFKPTAAFAELLPKEQ
Protein: RING-type domain-containing protein (Q586K9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFSGNPYITPAEFIYASEGNVAALRTWLQSNRERVNLPNPNTRHTLLYTATCADRGSVVAMLVTEFNADISVPCGAIDNTCLHVAAEHCNEDILSFLLSFGIPPKRNALNQLPLDLARQQLGRHPSAQNCIVMLQMVEEQPDKQGLTSATETFNPFMSITQPVSSADQLRPSAYQSPMSGGEFNYSDLLEREKQWLAVDSVAASSPGGLPSAQRVKKWYEGMPRDTRHLDRSKPLPYDLQELRRAYKGVFKFYETCQNYRAQGMLPYKYNGEMYYTPVILVVTKTHAGDRYKSGSESGVNPSTSDKDRTALTSSCVLDNSSGVRSSPYRALIDIKALAGLSINRRATYIDPRSGAIIPSSADAKVRSLVQYVSDVILANFSLIAPLTRSNESTKVVNNSGPLFYPFSHRREITTRVLRALSQFCDNAFTYDAVTCTAEGHLPITKVSPFSSASVDLHEPTVTSGGISKAAPLDLLEGDVVMKLPLRIKFDPNGDFTDAPRLYFPTALDSSPERRALQPIIEDSTSGKLDLRNFTSIQDWSTHGSLQAVLKEVQEKATDLIVKYCKENPGPAHSASGSGGSFEPSENSAVTPALSPIAAGSGSSQHVRAHGHSTAETHVKERELSTKCVTCLDAEKDVLLLPCRHLALCSTCSVTYIERQMDGMLCPICRVVVEQAMQIYT
Protein: Olfactory receptor 1J21 (Olfactory receptor 136-6) (Olfactory receptor 50) (Olfactory receptor I-D3) (Q8VGK5)
Organism: Mus musculus (Mouse)
Function: Odorant receptor. Activated by (+) and (-)-carvone.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MMKSNQSTVSEFILLGLPIQPEDQAVYFALFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISHAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHPLHYTTIMSQSLCVLLVMVSWAFSSSNGLVHTLLFARLSLFRDNTVHHFFCDLSALLKLSSSDTTINELVILTLAVVVITVPFICILVSYGHIGATILRTPSIKGICKALSTCGSHLCVVSLYYGAIIGLYFFPSSNNTNDKDVIVAVLYTVVTPMLNPFIYSLRNRDINGALRKTLSRRLCSH