wanglab/gogpt-training-data huggingface dataset:
Protein: Probable pterin-4-alpha-carbinolamine dehydratase, chloroplastic (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (PCD/DCoH-like protein 1) (Protein AIRP2 TARGET PROTEIN 1) (Protein SDIR1-INTERACTING PROTEIN 1) (Q9LU63)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in tetrahydrobiopterin biosynthesis (By similarity). Interacts with and acts downstream of the E3 ubiquitin-protein ligase SDIR1 in abscisic acid (ABA) and salt stress signaling. Regulates the expression of the bZIP transcription factor ABI5, which mediates responses to ABA during seed germination and salt stress. The SDIR1-ATP1/SDIRIP1 complex plays an important role in ABA signaling through the ubiquitination pathway. Acts downstream of AIRP2 in regulation of ABA signaling during drought stress.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:18245455, ECO:0000269|PubMed:25616872}. Cell membrane {ECO:0000269|PubMed:25616872}; Peripheral membrane protein {ECO:0000269|PubMed:25616872}. Nucleus {ECO:0000269|PubMed:25616872}.
Interaction partners:
- E3 ubiquitin-protein ligase SDIR1
- E3 ubiquitin-protein ligase AIRP2
- E3 ubiquitin-protein ligase AIRP1
- Homogentisate 1,2-dioxygenase
- E3 ubiquitin-protein ligase RMA1
- RING-H2 finger protein ATL14
- E3 ubiquitin-protein ligase KEG
- Probable E3 ubiquitin-protein ligase XERICO
Sequence:
MAATSSSPPCNISASSLLLRQPSRSILKVFGLLPPVSRNNRKLGRLTVTRSNLAQDFLGDFGARDPYPEEIASQFGDKVLGCQSTEHKILIPNASVLSLSQLQCSPVSSSQPPLSGDDARTLLHKVLGWSIVDNEAGGLKIRCMWKVRDFGCGVELINRIHKVAEASGHYPSLHLESPTQVRAELFTSSIGGLSMNDFIMAAKIDDIKTSDLSPRKRAWA
Protein: Uncharacterized protein (Q583S1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWFSRFSLSLASTDAGEKLLRSIRGRDITLRVSTKDGNARIVFASTTNLLRETMRRHKLLTRMKGQTPFLELVGTHLTFTNILAALQEGEERVATRLSANEGTIVTESLAIGECRCYVGGHNGTTLEEEPHFPLKVDRFLYGQSQPFSSITAASLTQLIDRDYNATVSSSEGFCSTAQTPETAVPLLGLGMLSPEVVDAYYRRNITLHGHTFFRQSEGSVAALWCCAYLDDPSLLEAFALYSEASAASESPEAVDRVDEMMRKTACSCGVLVQPVVAGRVVEEKIHLLQRLLVRASIVQPEIFSVLKERGVHEGLACQDSIALVTGDHEGAYEVAKAARQFTQDPSVSAPVVEKVREGLGLDKGERFFIDQASVVRNGIDYFCRCSKNNFLRALVALPEEQLSSLMEETSFRCTFCAKEHVLQPEDWSKLLRDRTSFKK
Protein: E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (A0A8I5ZWU2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAGNVKKSSGAGGSGSGGSGAGGLIGLMKDAFQPHHHHHHHLSPHPPCTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTVLSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQASSSSLHKDKPLPIPPTLRDLPPPPPPDRPYSVGTETRPQRRPLPCTPGDCPSRDKLPPVPSSRPGDSWLSRPIPKVPVATPNPGDPWNGRELTNRHSLPFSLPSQMEPRADVPRLGSTFSLDTSTTMNSSPVAGPESEHPKIKPSSSANAIYSLAARPLPVPKLPPGEQGDSEEDTEYMTPTSRPVGVQKPEPKRPAETAQSSRACDCDQQIDSCTYEAMYNIQSQALSVAENSACGEGNLATAHTSTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGEPTNFNEGSQVPERPPKPFPRRINSERKASSYQQGGGAMANPAAAAPSPQLSSEIERLMSQGYSYQDIQKALVIAHNNIEMAKNILREFVSISSPAHVAT
Protein: Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)) (P23378)
Organism: Homo sapiens (Human)
Function: The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:28244183}.
Interaction partners:
- Aminomethyltransferase, mitochondrial
- Glycine cleavage system H protein, mitochondrial
- Serine hydroxymethyltransferase, mitochondrial
- Serine hydroxymethyltransferase, cytosolic
- Dihydrolipoyl dehydrogenase, mitochondrial
- Myosin-binding protein H
- Sarcosine dehydrogenase, mitochondrial
- Glycine cleavage system H protein
- Glycine cleavage system H protein
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase
Sequence:
MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATLHAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYTGVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSEGLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINFRLFEDGTLGISLDETVNEKDLDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEKDLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFLPNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYMAKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHWDRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS
Protein: Protein rogdi (Q9VVE2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in promoting sleep by enhancing metabotropic transmission of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in GABAergic neurons upstream of a wake-inducing dopaminergic pathway.
Subcellular location: Nucleus envelope {ECO:0000250|UniProtKB:Q9GZN7}. Presynapse {ECO:0000250|UniProtKB:Q4V7D2}. Cell projection, axon {ECO:0000250|UniProtKB:Q4V7D2}. Perikaryon {ECO:0000250|UniProtKB:Q4V7D2}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q4V7D2}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q4V7D2}. Note=Detected primarily at presynaptic sites on axons, and to a lesser degree in soma and dendrites. Not detected at post-synaptic sites. {ECO:0000250|UniProtKB:Q4V7D2}.
Interaction partners:
- Rabconnectin-3A
- V-type proton ATPase subunit E
- V-type proton ATPase subunit B
Sequence:
MKMLADTEREEALNLQIEFEWVLRQEVHAILKQLRSILVECAHRFPVPLYENEGKKTEKFILTVSPDQLKAVLTLTGDAITQADISFKLCKAPSQTQRTSITHDSPWKLQQVQDAANHLQTAINHIDDVDDSYHFKTSDEVLHVIGNILDALQRGRNSLLVPKKKPIDELIKGRNMKSLVPNLPEDLAVSFYLQSHKLIIAVYQLLNNQGTMRFDSRQAEASVQWLNDVLLLLMNGQKLCQQLKDKISVFSVYKDFTVGSRSPSALSY
Protein: Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) (P53609)
Organism: Homo sapiens (Human)
Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B.
Interaction partners:
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Hairy/enhancer-of-split related with YRPW motif-like protein
- Geranylgeranyl transferase type-2 subunit alpha
- Coiled-coil domain-containing protein 112
Sequence:
MAATEDERLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLLDLHQSWKTKDSKQCSENVHIST
Protein: Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma) (F1RME6)
Organism: Sus scrofa (Pig)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
Sequence:
MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGGPAANPDAAAGLPSASAAAVNADFMSNLSLLEESGDFQQAPGSVAAAAAAAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQQPPPPGPLSQHPPVPPAAAGSLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKASLQSGQEGAGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGDGDVHSMVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTIMQQTPCYSFAPPNTSLNSPSPNYQKYTYGQSSMSPLPQMPMQTLQDSKSSYGGMAQYNCAAGLLKELLTSDSPPHNDIMTPVDPGVAQPNSRVLGQNVLMGPSSVMPAYGGQASHNKMMNPSSHSHPGHAQSTSAVNGRALPHAVNTMPHASGMNRLAQAKTALQVPLPHPMQMNALGGYSPASTCNGYGRMGLLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG
Protein: Id2 (Inhibitor of DNA binding 2, HLH protein) (O73933)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Oligodendrocyte transcription factor 2
Sequence:
MKAFSPVRSVRKNGLSEHNLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPSIVSLHHQRPGQNAASRTPLTTLNTDISILSLQAAEFPSELMASDSKALCG
Protein: Kinesin-related protein 3 (Kinesin family member 3) (Kinesin-1) (Q54UC9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end. The maximal velocity in an inverted motility assay (moving microtubules on fixed motors) was 1.96 um/s.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18160177}. Note=Local concentrations were found in vesicular structures around the nucleus in live cells.
Interaction partners:
- Lis-interacting protein
- Kinesin-related protein 1
- Tubulin beta chain
- Kinesin-related protein 2
Sequence:
MSSIRVVCRFRPQNKLELAQGGDSIVSIAPENDSVTINGSESNHSFSFDYVFPSNTTQRDVYDHAAKPVIEDIMAGYNGTLFVYGQTGSGKTFSMTGINDPNGDQELRGIVPRMIETVFEFISNADENIEFIVKASYIEIYMERIRDLLDTRKDNLKVREEKGKGVWVEGTSEVYIYREEDILDVINTGISNRAIAETRMNAESSRSHSIFILTIQQKNLKVGSIKTGKLYLVDLAGSEKISKTGAQGTTLDEAKMINKSLSSLGNVINALTDGKSTHIPYRDSKLTRVLQESLGGNSRTTLIINCSPSSYNEAETISTLRFGSRAKNIKNKAKINQERSAAELKILLSKAENEIENLKGYIKELETVSGVTVSNLKSSGSGSGSGSGSSSSSSGSSGGSGSGGSSNLSNSVNSTSNLNTSSNTSSSNVNANANVITTSVSAPTSPKDTELIKVLQEKCIQLEKQLFKKEEEKKEILEQLEQQQEQIQDKDQEIEGLNSMIESSNNINSLYQNSTNENSVLNVQLSELKLALEKSRFEATEQSLTIEGLNEENQSIKSQLEILKDRIAQSGDSSIASLVPSTPKSSAEMDPLATASKHADEWNEKAEQLKLLQRTPSKAVGSSKSNTATSSPIISLNISESDNIGSGATTTTNNNNATITPATSSNNNVEQQQQQVEELLPSVNEQLLESENQKLQKRIQEIELEFETYKIAKENLTMQKDLEIEQLLESQRISSSFVVDPRNLDDELPAEMMLQAEQIRKLIAENSEQKVHFEATKNENSKLKNRIEMIEEETRQRMEEELNVLREQTNQKLSEFGSLKESLIRDLENRCQKVIDLELVLDELQDRIVTLNERLKRVNKPGGGDQEAAFVQSKLDEITAVKHQLVIENNKHKTEVERLKKLLSHRGEHILILEKTMAINQESLFKLALNHNALTIEHDRAKNELEKLNNLLSQVGVDAQNTGGARVARVIRGGGGNNQLKKFNHSSSSSTSSSSALNHSSINNNHTTPTPLSANLYSNTKRSTKELNTGVKAEPLSLSGSPFNTSIPSSPNHTSSNNINNNSNNNNNNNNNNNIGNSGNIGGVGNNNSSISNSNNNSSSNLNANLNGNTPVKITSENSSSSLWNIFKKKSPSSTPPSSTNNLSPQSPQTPSHLSADGSGNISPNLSPPIPVNFSYTPAVVTSSTINKDQQKD
Protein: Protein FAM124A (Q86V42)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDPKAGGGGEEDDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDNVLAWIHPDLPLFRVSERRASRRRRKPPKGAQPALAVVLFLQEEYGEEQILQLHRTLQQPPWRHHHTEQVHGRFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTVYCRYDNYADSLRFYQLILRRSPSQKKADFCIFPIFSNLDVDIQFSLKRLPCDQCPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRVHKKFPKPGRVHHASEKKRHSTPLPSTAVPSHTPGSSQQSPLNSPHPGPIRTGLPPGHQQEFAGRANSTPNPPWSFQRSKSLFCLPTGGPSLASSAEPQWFSNTGAPGHRASEWRHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSTVETPLPSERCSSHWAAHKDSREGPLPTVSRVTTEASWASLPFFTKRSSSSSATARAAPPAPSTSTLTDSSPQLPCDTPKVKQTDGDMPPPPGSAGPGDNDMEEFYI
Protein: Cytokinin riboside 5'-monophosphate phosphoribohydrolase (EC 3.2.2.n1) (Protein LONELY GUY homolog) (LOG homolog) (O05306)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the hydrolytic removal of ribose 5'-monophosphate from nitrogen N6-modified adenosines, the final step of bioactive cytokinin synthesis. Is involved in the synthesis of isopentenyladenine (iP) and 2-methylthio-iP (2MeS-iP), the most abundant cytokinins detected in M.tuberculosis lysates and supernatants. Is also able to convert trans-zeatin-riboside monophosphate (tZRMP) to trans-zeatin (tZ) in vitro; however, it may not be involved in the biosynthesis of this minor cytokinin in vivo. Accumulation of Rv1205 sensitizes M.tuberculosis to nitric oxide since cytokinin breakdown products synergize with NO to kill M.tuberculosis. Shows a slow AMP hydrolase activity, but is not able to hydrolyze ATP. Displays no lysine decarboxylase (LDC) activity (L-lysine conversion to cadaverine).
Interaction partners:
- tRNA dimethylallyltransferase
- Medium/long-chain-fatty-acid--CoA ligase FadD6
- Glucosyl-3-phosphoglycerate synthase
- TIGR00725 family protein
- Inactive dihydropteroate synthase 2
Sequence:
MSAKIDITGDWTVAVYCAASPTHAELLELAAEVGAAIAGRGWTLVWGGGHVSAMGAVASAARACGGWTVGVIPKMLVYRELADHDADELIVTDTMWERKQIMEDRSDAFIVLPGGVGTLDELFDAWTDGYLGTHDKPIVMVDPWGHFDGLRAWLNGLLDTGYVSPTAMERLVVVDNVKDALRACAPS
Protein: Protein FAM76B (Q5HYJ3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:19266028, ECO:0000269|PubMed:27018871}.
Interaction partners:
Sequence:
MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHSSSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP
Protein: WD40 repeat-containing protein HOS15 (HIGH OSMOTIC STRESS GENE EXPRESSION 15) (Q9FN19)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as repressor of cold stress-regulated gene expression. Interacts specifically with and promotes deacetylation of histone H4. Plays a role in gene regulation for plant acclimation and tolerance to cold stress.
Subcellular location: Nucleus {ECO:0000269|PubMed:18356294}.
Interaction partners:
- Histone deacetylase 9
- Histone deacetylase 6
- Histone deacetylase 19
- PX domain-containing protein EREX
- PX domain-containing protein EREL1
- PX domain-containing protein EREL2
- Duplicated homeodomain-like superfamily protein
- Cullin-4
- Histone deacetylase 7
- Histone deacetylase 17
Sequence:
MSSLTSVELNFLVFRYLQESGFTHAAFTLGYEAGINKSNIDGNMVPPGALIKFVQKGLQYMEMEANLSNSEVDIDEDFSFFQPLDLISKDVKELQDMLREKKRKERDMEKERDRSKENDKGVEREHEGDRNRAKEKDRHEKQKEREREREKLEREKEREREKIEREKEREREKMEREIFEREKDRLKLEKEREIEREREREKIEREKSHEKQLGDADREMVIDQTDKEIAGDGSTGAEPMDIVMTPTSQTSHIPNSDVRILEGHTSEVCACAWSPSASLLASGSGDATARIWSIPEGSFKAVHTGRNINALILKHAKGKSNEKSKDVTTLDWNGEGTLLATGSCDGQARIWTLNGELISTLSKHKGPIFSLKWNKKGDYLLTGSVDRTAVVWDVKAEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDSMIYLCKIGETRPAKTFTGHQGEVNCVKWDPTGSLLASCSDDSTAKIWNIKQSTFVHDLREHTKEIYTIRWSPTGPGTNNPNKQLTLASASFDSTVKLWDAELGKMLCSFNGHREPVYSLAFSPNGEYIASGSLDKSIHIWSIKEGKIVKTYTGNGGIFEVCWNKEGNKIAACFADNSVCVLDFRM
Protein: Conserved protein (O07222)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized protein Rv1352
- Putative lipoprotein LppO
Sequence:
MQLQRTMGQCRPMRMLVALLLSAATMIGLAAPGKADPTGDDAAFLAALDQAGITYADPGHAITAAKAMCGLCANGVTGLQLVADLRDYNPGLTMDSAAKFAAIASGAYCPEHLEHHPS
Protein: Electron transfer flavoprotein subunit beta (Beta-ETF) (Electron transfer flavoprotein small subunit) (ETFSS) (P9WNG7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
Interaction partners:
- Electron transfer flavoprotein subunit alpha
- Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH
- Possible acyl-CoA dehydrogenase FadE19
- Probable acyl-CoA dehydrogenase FadE25
- Probable acyl-CoA dehydrogenase FadE13
- Probable acyl-CoA dehydrogenase FadE21
- Possible acyl-CoA dehydrogenase FadE16
- Probable acyl-CoA dehydrogenase FadE18
- Probable acyl-CoA dehydrogenase FadE3
- Probable iron-sulfur-binding reductase
Sequence:
MTNIVVLIKQVPDTWSERKLTDGDFTLDREAADAVLDEINERAVEEALQIREKEAADGIEGSVTVLTAGPERATEAIRKALSMGADKAVHLKDDGMHGSDVIQTGWALARALGTIEGTELVIAGNESTDGVGGAVPAIIAEYLGLPQLTHLRKVSIEGGKITGERETDEGVFTLEATLPAVISVNEKINEPRFPSFKGIMAAKKKEVTVLTLAEIGVESDEVGLANAGSTVLASTPKPAKTAGEKVTDEGEGGNQIVQYLVAQKII
Protein: M-phase phosphoprotein 6 (Q99547)
Organism: Homo sapiens (Human)
Function: RNA-binding protein that associates with the RNA exosome complex. Involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and play a role in recruiting the RNA exosome complex to pre-rRNA; this function may include C1D.
Subcellular location: Nucleus, nucleolus. Cytoplasm. Note=Cytoplasmic in M phase.
Interaction partners:
- Exosome complex component RRP41
- Exosome complex component RRP42
- Exosome complex component RRP43
- Exosome complex component RRP46
- Exosome complex component MTR3
- Exosome complex component CSL4
- Exosome complex component RRP40
- Exosome complex component 10
- Exosome complex component RRP45
- Exosome complex component RRP4
Sequence:
MAAERKTRLSKNLLRMKFMQRGLDSETKKQLEEEEKKIISEEHWYLDLPELKEKESFIIEEQSFLLCEDLLYGRMSFRGFNPEVEKLMLQMNAKHKAEEVEDETVELDVSDEEMARRYETLVGTIGKKFARKRDHANYEEDENGDITPIKAKKMFLKPQD
Protein: Cystathionine gamma-lyase (gamma-CTLase) (EC 4.4.1.1) (Gamma-cystathionase) (Sulfur transfer protein 1) (P31373)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the production of cysteine from cystathionine in the reverse transsulfuration pathway for the biosynthesis of sulfur-containing amino acids cysteine and methionine. In this pathway, homocysteine sulfur is converted to cysteine sulfur (Probable). Also has cystathionine beta-lyase and cystathionine gamma-synthase activities in vitro. Cystathionine beta-lyase may be physiological, while cystathionine gamma-synthase activity is not, as the required substrate O-succinyl-L-homoserine(OSH) does not occur naturally in S.cerevisiae.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Cystathionine beta-synthase
- 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- Putative cystathionine gamma-synthase YML082W
- Putative mitochondrial cysteine synthase
- Cystathionine gamma-synthase
- Homocysteine/cysteine synthase
- Thiosulfate sulfurtransferase TUM1
- Homoserine dehydrogenase
- Glutamate--cysteine ligase
- Adenosylhomocysteinase
Sequence:
MTLQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLERAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETSFTNDLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNTFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVFDDLVRISVGIEDTDDLLEDIKQALKQATN
Protein: Kinetochore Mis12-Ndc80 network component 2, isoform D (E1JJ86)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MENFSLQQLIELQNIQKELNSNKDTYLKTYRQVLKKKFRSELNNLVRADFNIVKTELKVPQLPPLPPEDEKTTATFSDMAKDYEFTKDCLSLL
Protein: Fluoride export protein 1 (P0CU19)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q08913}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized protein PB16A4.07
- Probable L-asparaginase 2
- Uncharacterized exonuclease C637.09
- Uncharacterized protein C25B8.20
Sequence:
MLLTQSYFCIMSMLGTLARLGLTALNTYPGAPFSGLLWVQFVGCVIMGFCQTESVFFPRPKHNATFLLAITTGFCGSLTTFSSWMLQMFTGMANLDPFERRGRGYSFLSVVSDFMVTMCIAMSSLIWGKQIGKTTGQWRIGKVAFAWPIPAHTHIVVRVLLLLLSICFFVGAAFYTAYTTNVTHRGIGFSLIFSPFAALTRLYLARFLNSPQYFIPYGTLCANVFATLLLSIMYMIPQITHCTPVSRSVMYGIQNGFCAVLSTLSTFSNELHTMPIKRAYIYCIISVAISFSICVIVDGATAWGHGYTEKY
Protein: Nuclear pore complex-interacting protein family member B13 (A6NJU9)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKVINTLADHHHRGTDFGGSPWLHVIIAFPTSYKVVITLWIVYLWVSLLKTIFWSRNGHDGSTDVQQRAWRSNRRRQEGLRSICMHTKKRVSSFRGNKIGLKDVITLRRHVETKVRAKIRKRKVTTKINHHDKINGKRKTARKQKMFQRAQELRRRAEDYHKCKIPPSARKALCNWVRMAAAEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSITDNSLSLKTPPECVLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSAPPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAFHPQRMIISRHLPSVSSLPFHPQLHSQQMIISRYLLSVCGFRFHHQPMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPQRMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGGRFHPQRMIISRHLPSVSSLPFHPQLHPQQMIISRHLPSVCGERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRRPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPPLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKPKRRRAADVEPSSPKPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRRRLS
Protein: Uncharacterized protein C3orf36 (Q3SXR2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQAETILEGLEAGLPQAVSSGLSLVPAPGLVLTCLSAPSGPGGMALEPPPTTLRKAFLAQSTLLESTLEGAPEWAAPHPEEQRRSPPACSQHTPPLPSTPTGPPPCSPGGNHPLCALSGRGGGRCSIPSLSSSSTFSLFSSGCWNPRVKLRVRKSQSQGRAGQLI
Protein: Immune-induced peptide 18 (DIM-18) (P82701)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000269|PubMed:9736738}.
Interaction partners:
Sequence:
MKLIALCCLLLLGLLGFLAAPGVASPSRHTGPGNGSGSGAGSGNPFRSPSSQQRPLYYDAPIGKPSKTMYA
Protein: Os06g0607900 protein (Q69V64)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Two pore calcium channel protein 1
Sequence:
MNYLAKMRKEVGKKINLRSAQTNAAFRKLFNLPPEEFLIDDFTCHLKRKMPLQGRLFFSPRIIGFYSNIFGHKTKFFFLWDDVDDIQVIPPTLSIGSPSLTIILRKGRGLEAKHGAKGTDPNGRLKYYFQSFVSFNDAHRIIMAIWKMRSLSPEQQGDMIEKESDTKELQLEEGGTLFTHEDVKMSEIFSSALSVDVESLMEMFSGGPLEHRMMQKAGCIDYSPTEWELVSRNIYQRQISYKFDKNLSRYGGEATTTQQRYALVNQEGWAIEEVMSLQGVLLGDCFNVQMKYTVVNVPSKPNTCSVQVLLGIAWLKSTKQQKKITKSVISNSSIRLKELFAEVEKDLTSRSGAS
Protein: Universal stress protein PHOS32 (Phosphorylated protein of 32 kDa) (AtPHOS32) (Q8VYN9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Transducin/WD40 repeat-like superfamily protein
- TCP-1/cpn60 chaperonin family protein
- Calmodulin-binding protein 60 E
- Tetratricopeptide repeat protein SKI3
- Carbohydrate-binding-like fold
- Calmodulin-binding protein 60 D
- Mitogen-activated protein kinase 3
- At1g58270/F19C14_8
- At1g13730
- Mitogen-activated protein kinase 6
Sequence:
MNPADSDHPQLPNIKIHHPPSPRHSHHHHSSSTPSSAATPTPTAGARRKIGVAVDLSEESSFAVRWAVDHYIRPGDAVVLLHVSPTSVLFGADWGPLPLKTQIEDPNAQPQPSQEDFDAFTSTKVADLAKPLKELGFPYKIHIVKDHDMRERLCLEIERLGLSAVIMGSRGFGAEKKRGSDGKLGSVSDYCVHHCVCPVVVVRYPDDRDGPVPIVTVKSGGDDDGDVVAASASAHHEHIKDE