wanglab/gogpt-training-data huggingface dataset:
Protein: Arpin (Q1LWJ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors (By similarity). Involved in steering cell migration by controlling its directional persistence.
Subcellular location: Cell projection, lamellipodium {ECO:0000250}.
Interaction partners:
- AP-3 complex subunit delta-1
- AP-3 complex subunit sigma-2
- AP-3 complex subunit mu-1 isoform X1
- AP-3 complex subunit mu-2.
- Adaptor-related protein complex 3 subunit beta 1a.
- Adaptin_N domain-containing protein.
- AP-3 complex subunit beta.
Sequence:
MSRIYDNTALLNKPVHNEKLSFTWDPIVHQSGHGVILEGTVVDFSRHAITDVKNRKERYNVLYIKPSRVHRRKYDSKGNEIEPNFSDTKKVNTGFLMSSYKVEAKGETDCLDERQLREIVNKEQLVKVTIKHCPREAFAFWISEAEMDKTELEPGQEVRLKTKGDGPFIFSFAKLDSGTVTKCNFAGDENAGASWTEKIMANKSNQENTGKSAAQGEGADDDEWDD
Protein: NAD(+) kinase (EC 2.7.1.23) (A0A8I6AFT7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MCSFWKDSTQVSGVPTREHPDCSSTSVFFISTMEMEQEKMNLSKELNPDSASYNCSACHGDETWSYNHPIRGRAKSRSLSASPALGSTKEFRRTRSLHGPCPVTTFGPKACVLQNPQTIMHIQDPASQRLTWNKSPKSVLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKVLEDPAIVGDENFGPVKKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEPRDKKTAIHNGLSENGLDTEGGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVCDPVSDWFESLAQCLHWNVRKKQAHFPEDEEDQDEEDS
Protein: Disco-related, isoform A (Disco-related, isoform B) (Disco-related, isoform C) (Disco-related, isoform D) (Q9VXJ5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNIGHEKHPPHFHPHPQPHPHPRAAAASEVHRLAAGGSVSPPPPPSTSSSLLYHLPANTNAATAATVATVSASYRHPLQGHERQQNQHHHPYQHQHHHHYHQHHPHLPTGGGNVHLSRESSPASMVMTPSRRSSPPLPPLPLTTHPIHPHSHSHSHPHPHPHPLPLALPLRHPLALNANAGGHQSPSRSSGSVQQTSSHAQSSAQSMSVHFSQLAHAQLHLQNQLQQKLSAAASRNNNNNNNNNNNNSSSTGSGTGTGNSTPTHDPNPMNPLSDLQNMQPFDFRKISSAAALGAFGGPLPLPQSPTEFGQHHHHSQQQQHQHHLHRNQFFNAMAMAYHLPPPPPPPPPDSRSPPSPPPGVGQYQHQAGSGSGSGSGSGSGSSSGAGSVDDSAGKQQRNSDKVSASGSCSSSQRMTRLALSSNMRSSRKTPHSPGGGGAGGNGGSVGGGGGKRQWGSMPANLGTQFINPVTGKKRVQCNVCLKTFCDKGALKIHFSAVHLREMHKCTVDGCSMMFSSRRSRNRHSANPNPKLHSPHLRRKISPHDGRSAQPHPLLLQAPNGLMAGLAPFGSFPLLTPPPDLRHHAMGGSGAGSGAGVGALELKHGQDYLQRSYLDAGRFEGQRRKLAMENEHTEDEDDDEILEVGIHMAGDDDDDEADGDEDEDDDDPDGIVVVGDEIDSMPLDHENDNDNENENDESDERSTSAVSSLSQTKEQSSPGKVVQSGLEECHTYAHAHAHALTHGHAHSLGHAHALAQMAANKRKRKSQNPVRCPVQSDENSGENSIDYDVAADLSIKKVRLPAQAAASAKESEVGESTKSIPSPPLTPYGDLRPVGLCIKTEQDHEQELDQEQGQERKREQEQEPEPDPVATASKSEMKLEEQETRPADKEDDNEEDEQVSPPVVTTLDLSRAAAAIKLEPLEEINYEADENRYVRIKQELMGGDESLAEESSDKTANHNNNNNNNNNININNSVRLESDNGLEASELEEREPEPETEIEPEHEHEHEPEPETEVEVPEVPIDKENPLKCTACGEIFQNHFHLKTHHQSVHLKLHHKCNIDGCNAAFPSKRSRDRHSSNLNLHRKLLSTSDDHGLLHAPVMPATDPLLELMSLNLNNNKSGFHHSAMVGSSAGGAGGVNPAAVGSIQAEILARICAGAHAHGLNVPLCFEALQHRFAVGHGHAGYPLIAGDGSPPSPRLFLNHGGGASPLLFAGLPRMPRFPQLTPHMLAASAGNTAAAAAAAAAAAAGMGGLSPFCRRTSSDSNSQHSITPPPKRSRSQSRSPDHCVHPAHAGDTTGITEDSGQRQSPDRIS
Protein: Asteroid homolog 1 (O14061)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Secretory component protein psh3
- Adenine DNA glycosylase
- DNA repair protein rad60
- Very-long-chain 3-oxoacyl-CoA reductase
Sequence:
MGVPRLGRFLEPFGKPVYFSSYPEVPLNCSLVIDGPSFAFWLWFSQGIVCSDFQGYQKAVLDFHHLLSRLRFKEIEYIFDGGLPFSKHQVRVNRYQQKINDLRSAYINLCVPIAQHVLMGLAKAKVIVCNEEADKYCAFQAKKLDAVILSQDSDFLLYDIDTPHYGYIPLQSLDVTSNGISGRKYRFDEIQKDFHFDLHILAAYLGVEGHPLDLVIDYHNTFEHICKILENSVKDKFIEKLVSKEELTRVHAFYSLNDLKLETSTINTFMWGRVQELLNSQLQPAEIWLPQLLELPSKHCSWLESAPLRLQAYANFSKQMPEFGTEVLEYFRLSDRLSKRLISVDYDYATVCETLDSKFSNWNLPHRLVLWTLRCMKNLNNITATSFLLMHVSLFLGSPMNLQPVEPTQEDIASVSRFIATIYSICMLIFSEDKEQSSISFQEFVSFSPLSSTLNFALFHQAASKLKTGKSPLSIVTDKTTASLTYKMYKDLTNDYSDIYMIMDIWKPKRKRKTKKDQS
Protein: Beta-caryophyllene synthase (LaCARS) (EC 4.2.3.57) ((-)-beta-caryophyllene synthase) (U3LVZ7)
Organism: Lavandula angustifolia (Lavender)
Function: Sesquiterpene synthase that catalyzes the formation of sesquiterpenes and sesquiterpenoid alcohols. Converts farnesyl diphosphate (FPP) to beta-caryophyllene. Can use geranyl diphosphate (GPP) to produce myrcene, limonene and camphene.
Interaction partners:
Sequence:
MAAPISTNNVCSDDARPVTYHPNVWSDYFLRYTSELTEISVAKKEEHERQKEAIRNLLLQTRDDSTLKLELVDAIQRLGIGYHFEEEIHNSLRNIYDTNPIYNAEDDNLRVAALRFRLIRQQGFPAPCDVFRKFVDEEGEFKSWVSNDVEGLLNLYEASNFAVHGEEILEKALEFCSLRLEFLTQGMTNSLSMRVKEALKIPISKTLTRLGARKFMSMYQEDESHNETLLNFAKLDFNLVQKIHQKELNQITRWWKELDFGKNLPFARDRPVECYFWIVGVYFEPRYGIARTLLTKIIYLASVLDDIYDVYGTLAELTIFTQIIRRWDSDAMDQLPPYMRIYCKALFDVYVEMEEEMGKIRKSYAVEYAKKEMKRLAEMYFQEAQWAFSKYKPTMKEYLKVALISSGYMMMTINSLTTIEDLITEEEFNWILSEPRILRASLTITRLMDDLAGYGTEGKMSAVHYYMAENGVSEGEAFKEVSGIIKSAWKDVNAECVEPRAASTTILRCVVDFTRVIVLLYSDEDAYGNSQTKTKDLIKSVLVDPLII
Protein: Nucleolar GTP-binding protein 1 (F4I4A6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR038919}.
Interaction partners:
- 60S ribosomal export protein NMD3
- Probable ribosome biogenesis protein RLP24
- Nuclear/nucleolar GTPase 2
- Pescadillo homolog
- Ribosome assembly factor mrt4
- Ribosome production factor 2 homolog
- AT5g04600/T32M21_200
- Ribosome biogenesis protein BOP1 homolog
- Ribosome biogenesis protein WDR12 homolog
- Nucleolar complex-associated protein 3
Sequence:
MTIVSTCCPFGLSNVTKCINFVQIKEAKTMVKYNFKKITVVPNGKQFVDIVLSRTQRQTPTVVHKGDRICKLRSFYMRKVKFTESNFNEKLSAIIDEFPRLKEIQPFYEDLLHVLYNKDHYKLALGQVNTAKNKISKIAMDYVKLLKHGDSLYRCKCLKVAALGRMCTVMKGIGPSLAYLEQVRQHIARLPSIDPNTRTLLICGCPNVGKSSFMNKVTRADVAVQPYAFTTKSLFLGHTDYKCLRYQVIDTPGLLDREIEDRNIIELCSITALAHIRAAVLFFLDISGSCGYTIAQQASLFHNIKSVFKNKPLVIVCNKTDLMPMENLSEEDRKLIEEMKDEAMKTEMGASEEAVILEMSTLTEEGVMSRLLDQRVAAKMKSKKIGDHLNRFHVAMPKSRDDQERLPCIPQVAGEKEKRKTEKDLEDENGGAGVYSASLKKNYILAKEEWKDDIIPEICDCHNVADFVDSDILNRLEELTSEESLRKAEEEEVGFEIEGEELTEKEKNDLAAIRKKKALLIEESRLKKSNAQNRAAVPRKFDKDKKFTRKRMGRELSSLGLDPSSALNRARSKSRGRKRERYDDLSNDAMDVDVNDDEQHKKKKMCLRSKSRSLSRSRSVSRPPHEVVPGEGFKDSSQKIKAIKIGHKSHRKRDKAARRGEADRVIPSLKPKHLFSGKRGNGKNQRR
Protein: Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (E9PLZ3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGL
Protein: Plant-specific TFIIB-related protein 2 (AtPBRP2) (TFIIB-related protein PBRP2) (Q9LIA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant-specific TFIIB-related protein involved in the regulation of endosperm proliferation during the syncytial phase of endosperm development. Does not contribute to RNA polymerase IV or V activities in reproductive tissues.
Subcellular location: Nucleus {ECO:0000269|PubMed:21390310}.
Interaction partners:
- Plant-specific TFIIB-related protein 1
- Transcription initiation factor IIF subunit alpha
- DNA-directed RNA polymerase II subunit 4
- Transcription initiation factor IIA subunit 2
- General transcription and DNA repair factor IIH subunit TFB2
- DNA-directed RNA polymerases II, IV and V subunit 11
- General transcription factor IIH subunit 2
- General transcription and DNA repair factor IIH subunit TFB4
- Transcription initiation factor TFIID subunit 1b
- Pentatricopeptide repeat-containing protein At4g30825
Sequence:
MEEETCLDCKRPTIMVVDHSSGDTICSECGLVLEAHIIEYSQEWRTFASDDNHSDRDPNRVGAATNPFLKSGDLVTIIEKPKETASSVLSKDDISTLFRAHNQVKNHEEDLIKQAFEEIQRMTDALDLDIVINSRACEIVSKYDGHANTKLRRGKKLNAICAASVSTACRELQLSRTLKEIAEVANGVDKKDIRKESLVIKRVLESHQTSVSASQAIINTGELVRRFCSKLDISQREIMAIPEAVEKAENFDIRRNPKSVLAAIIFMISHISQTNRKPIREIGIVAEVVENTIKNSVKDMYPYALKIIPNWYACESDIIKRLDGVITSWDSAKFSV
Protein: Interferon gamma (B3IXK1)
Organism: Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus)
Function: Cytokine which binds to interferon gamma receptor 1 (ifngr1). Also binds with lower affinity to interferon gamma receptor 1-like (ifngr1l). Has activating effects on macrophages and neutrophils (By similarity).
Subcellular location: Secreted {ECO:0000305|PubMed:29742458}.
Interaction partners:
Sequence:
MMVSTARAVVCLSLCLCVCQVRGSHIPARMNKTIQNLLQHYNISNKDRFNGKPVFPKEPLSGRMETKMLFMGGVLETYEKLIGQMLEQLPNTTPPTAGSREGLNSAAPEVSVRTDLNYILKKVQELRTNRFKEQSKLLQGLHDLGDIKMNNFIIQSKALWELQWMYEEASSLSNNTKMQRRRRRRRRQARKVKTPTRA
Protein: KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog) (A0A0B4KHH6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSSFSPNQLRQCARFTGTPCTPDKEHQLREQIHSELVKIKYCANPTYECSLMRIEGYEYCIRHILRDPRSNFRQCSHVYSNGRKCINAVAKYDNKKELILTTLCFEHNRQTQLQKTHMNVGRIRSRVETNETLLHSLSSHINVEDIKPEVKKIERDDDEIDVVSPHVTPFVTQDHRNSIGHVVESSRKRRRILDYASDSSSNDADPPCLRNTAQDIEFYESDHESIDSEDDDPLKHAGVFTRAEAVKIAETKLIKLQGLYREQISYLQNVLRQRRRKYLHDIRRERELYCSIHDQLKDTPHERKLYEQLKALNSYHRRQGVEAVLYKKLKEKRARDALYAAKSSSNPKCVFTEGGVKCGERTLPCCKHCRKHILEDKRQVLFRACGVERSGVVCQEPVASILEDSSCVLHLTVAPAKRQYIQKVR
Protein: Eukaryotic translation initiation factor 3 subunit E (eIF3e) (O94513)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential). Required for maintaining the basal level of atf1 and for transcriptional activation of core environmental stress response genes (CESR genes) in response to histidine starvation. May positively regulate proteasome activity. Required for nuclear localization of the proteasome subunit rpn501/rpn502.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03004, ECO:0000269|PubMed:11071922, ECO:0000269|PubMed:11071923, ECO:0000269|PubMed:11134033, ECO:0000269|PubMed:15904532}.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit H
- Eukaryotic translation initiation factor 3 subunit A
- Probable eukaryotic translation initiation factor 3 subunit J
- Eukaryotic translation initiation factor 3 subunit M
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 3 subunit F
- Eukaryotic translation initiation factor 3 subunit D
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit I
Sequence:
MGSELKSTSPLAVKYDLSQKIMQHLDRHLIFPLLEFLSLRQTHDPKELLQAKYDLLKDTNMTDYVANLWTNLHGGHTDEDMANAFAEKRRSVLQELSELEEEVQGILGVLENPDLIAALRQDKGQNLQHLQEHYNITPERIAVLYKFAQFQYNCGNYGGASDLLYHFRAFSKDPELNASATWGKFASEILTVDWDGAMEELGKLREMVDSKSFKDSAVQLRNRTWLLHWSLFPLFNHANGCDTLCDLFFYTPYLNTIQTSCPWLLRYLTVAVVTNQNNANQKPRNPRQSYQRRMRDLVRIISQENYEYSDPVTSFISALYTEVDFEKAQHCLRECEEVLKTDFFLVSLCDHFLEGARKLLAEAYCRIHSVISVDVLANKLEMDSAQLIQLVENRNNPSVAAASNVAADQSTEDESIESTSTNVVADDLITEAETATEAEEPEPEVQFGFKAKLDGESIIIEHPTYSAFQQIIDRTKSLSFESQNLEQSLAKSISELKHATV
Protein: CC-NB-LRR-type protein (R9RU01)
Organism: Oryza sativa subsp. indica (Rice)
Interaction partners:
Sequence:
MDAPASFSLGAMGPLLRKLDSLLVAPEIRLPKPLKEGIELLKEDLEEIGVSLVEHSVVDSPTHKARFWMDEVRDLSYHIEDCIDTMFSMRSGGDDGKPRSERRHKVGRAKIDGFSKKPKPCTRMARIAELRALVREASERLERYQLGDVCGSSSPVVFTADGRARPLHHGVSANLVGVDEFKTKLNRWLSDEEGPHLKVAAIVGPAGIGKTALATELYRDHRWQFECRAFVRASRKPDMQRLLGGILSQVQRRQRSSDAYADSTVQSLIDNLREHLQDRRYLIIIDGLWETAVWNIANSAFPDVNSFSRILITADIEQVALECCGYKYDYIMRMEPLGSLDSKKVFFNKVFGSEDQCPPELKEVLNTILEKCGGLPLAIISIAGLLGSQPENPVLWDYVTKYLCSSLGTNPTLKDVVKETLNLSYNSLPHPFKTCLLYLGMYPDGHIMLKADLMKQWSAEGFVSANEAKDTEEIVDKYFDELVNRGILEPVEINKNGKVLSCTLHHAVHDLVMPKFNDDKFTMSVDYSQTITGPSTMVRRLSLHFSSTRYATKPAGIILSRVRSLAFFGLLNCMPCIGEFKLLRVLILEFWGSHGEQRSLNLIPVCRLFQLRYLKTSGDVVVQLPAQISGLQYLETLEIDARVSAVPFDLVHLPNLLHLQLQDETKLPDGIGCMRSLRTLQYFDLGNNSVDNLRGLGELTNLQDLHLSYSAPSSNEGLMINLNAITSSLSRLSNLKSLILSPGAISMVIFFDISSIISVVPVFLQRLELLPPICIFCRLPKSIGQLHKLCILKVSVRELLTTDIDNLTGLPSLTVLSLYAQTAPEGRFIFKDGTLPVLKYFKFGCGELCLAFMAGAMPNLQRLKLVFNIRKSEKYRHTLFGIEHLVSLQDIATRIGVDTSTGESDRRAAESAFKETVNKHPRCLRSSLQWVVSTEEESHPLEKQHHKREKGSSAGHGVLEKESVEDSEKNTDRVQTLLSPQLSNMESVVESALTGQRTKIVVKVPCGKSRAKAMALAASVNGKSAQIYSSGCAVLISTPTSLCLYACRGEQRGDNGGGQRPAGGGRLWH
Protein: Acetylcholinesterase (AChE) (EC 3.1.1.7) (P21836)
Organism: Mus musculus (Mouse)
Function: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Subcellular location: Synapse. Secreted. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform H]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Interaction partners:
- Choline O-acetyltransferase
- Glycerophosphocholine phosphodiesterase GPCPD1
- Choline/ethanolamine kinase
- Acetylcholinesterase collagenic tail peptide
- Choline kinase alpha
- Phosphoethanolamine/phosphocholine phosphatase
- Amyloid-beta precursor protein
- Neuronal acetylcholine receptor subunit alpha-7
- Muscle, skeletal receptor tyrosine-protein kinase
- Basement membrane-specific heparan sulfate proteoglycan core protein
Sequence:
MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL
Protein: Tubulin beta-1 chain (Beta-1-tubulin) (P10653)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Tubulin alpha-1 chain
- Tubulin alpha-2 chain
- Dynein heavy chain, cytoplasmic
- Tubulin beta-2 chain
- RNase H type-1 domain-containing protein
- Miscellaneous Zn
- Cytoplasmic dynein intermediate chain
- Dis1/XMAP215 protein AlpA
- EB1 homolog
- Tubulin alpha chain
Sequence:
MREIVHLQTGQCGNQIGAAFWQTISGEHGLDGSGVYNGTSDLQLERMNVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGELFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVVDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICMRTLKLSNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAYSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVSMKEVEDQMRNIQSKNQSYFVEWIPNNIQTALCSIPPRGLKMSSTFIGNSTSIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASISEGEEEYAEEEIMEGEE
Protein: Estrogen receptor beta (W5UDK8)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR002527}.
Interaction partners:
Sequence:
MSSSLSPTLQTVNGMDQDEPLPLFPSHYPTSLGVDRGTVCIPSPYADNGHAEMSFCGPSAPENPAIAPPLSPSLFWSSHNPHAMPALPLHCPPALPYSEPHIHTAWVDTKPHTSGRHSSFLSRPKLFGKRPEDGDGDEALDDDDSSSSSSGAVVKRDMHFCVVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEMGMMKCGARRERCGYRASRRTAPMRDGSARPVGVRGQSQRLPHTPLHVSLSIPVSRASTESGFSGLSPEQLVYCILEAEPPQIYLKQQMKKPYTESTVMMSLTQLADKELVLMISWAKKIPGFVELSLAHQVQLLECCWLEVLMLGLMWRSIDHPGKLIFSLDLKLNRDEGNCVEGIMEIFDMLLAGSSRFRELKLQKEEYVCLKALILLNSSMYMTSSACEKDLESRTKLLRLLDAVTDALVWAISRTGLSTQQQSARLAHLLMLLSHIRHLSNKGMEHLSSMKRKNVVLLYDLLLEMLDANMAQSRHVSTSVCTDPVTPATSPNTPLPPQLHSPVAHHVTQVNESQCSQE
Protein: Chorismate mutase (CM) (EC 5.4.99.5) (Q9P4D8)
Organism: Pichia angusta (Yeast) (Hansenula polymorpha)
Function: Catalyzes the Claisen rearrangement of chorismate to prephenate. Acts at the first branch point in the aromatic amino acid pathway where it steers biosynthesis towards phenylalanine and tyrosine, and away from tryptophan.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P32178}.
Interaction partners:
Sequence:
MDFMKPETVLDLGNIRDALVRMEDTIIFNFIERSQFYASPSVYKVNQFPIPNFDGSFLDWLLSQHERIHSQVRRYDAPDEVPFFPNVLEKTFLPKINYPSVLASYADEINVNKEILKIYTSEIVPGIAAGSGEQEDNLGSCAMADIECLQSLSRRIHFGRFVAEAKFISEGDKIVDLIKKRDVEGIEALITNAEVEKRILDRLLEKGRAYGTDPTLKFTQHIQSKVKPEVIVKIYKDFVIPLTKKVEVDYLLRRLEDEEDDDATQKSGGYVDRFLSSGLY
Protein: LisH domain-containing protein (Q38BU5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNSFVSHSSPPLSAGINEMSLAELRLGIHEFLRSSGALGSLKTQLRGVITSELLKRRRTKDITAGECNSRELDAGADVSNKDGEGESAWIQRLADAIVEQHLRQTGRAFSLAIFSSEADVSFRATGDDALAVLLHLDNPVLTTAGWRAGPDSTPANAKVAHHRSSSFLQILTAAHLRHVGDSRGQRPRYAVGTQTDSDFGSEFSGESAKPPVEVRLAAVDAKYALCFARMEHSTREELDRHMETYREELKLQMEQTYQQRLRAFEQQKLLEVRREAEEHFRLLLQHKMEEQREIERLSAQRVEAERVRLSQAREDIQLQRVELERRQREIQLLLDERDKATVEMEGRLHDAKQQIRVLTSQLQQFEELCASRLAEAEAARDREMRRVGDIRRLQAEHVAELQLKDEEICRLRFRLKSLAASNTGGSWHHNALNTTENGVIMVHEVPSGATRQHKQGSRQQASHEATYLASTPVPREAAWQSIWHSTDVVGPTEVVTAPWRGEEGVVERRSHLVDPSLHSSDVHRQGKRGSRDTNDAAIESQERSMSIQPRRAATTESGSTVTTTSSRVGSRVLLADAAVAKSAHESATAEKQETPVPQECGSSERSGRAGNDEKDEVAHSKSSSGSTKVTRSNTTGEINGEVDRSHPPVVQGSHSEGPLSLNASEGNTAIASSSKMSSVRSHKSQSVTTPRAAASHALSDLVGRINAEEEDKRKEIEKEEETNRGGIKWAATSQHNLLVQRQTAMEEFSGREESNVVLLDRTTISDDGSEDDILYRKGDDSDDSI
Protein: Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (MST3b) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 35 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)] (B0LT89)
Organism: Rattus norvegicus (Rat)
Function: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12 (By similarity). Acts as a key regulator of axon regeneration in the adult optic nerve and radial nerve.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Membrane {ECO:0000250}. Note=The truncated form (MST3/N) translocates to the nucleus. Colocalizes with STK38L in the membrane (By similarity). {ECO:0000250}.
Interaction partners:
- Striatin
- Programmed cell death protein 10
- Striatin-interacting protein 1
- Striatin-3
- CTTNBP2 N-terminal like
- Striatin interacting protein 2
- Serine/threonine-protein kinase 25
- MOB-like protein phocein
- Suppressor of IKBKE 1
- non-specific serine/threonine protein kinase
Sequence:
MAHSPVQSGLPGMQTLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLEGSYSRPLKEFVEACLNKEPSFRPTAKELLKHKFIIRNAKKTSYLTELIDRYKRWKAEQSHEDSSSEDSDVETDSQASGGSDSGDWIFTIREKDPKNLENGTLQPSDLERNKMKDFPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGASAH
Protein: Aquaporin-5 (Q683N0)
Organism: Gallus gallus (Chicken)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004424}. Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004439}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004439}.
Interaction partners:
Sequence:
STLIFVFIGLGSALKWPSALPSILQISLAFGLAIGTLVQAFGHISGAHINPAVTIAFFVGNQISFLRTLFYVIAQLVGAIAGAGILYGVTPANTRGNLAINSLNNNTTPGQAVVVEMILTFQLAACIFASTDNRRYGNVGSPALSIGLSVAVGHLVGIYFTGCSMNPARSFGPAVIVRKFSSTHWVFWVGPILGACLAALLYFYILVPYCMNMSDRVAIVKGTYESEEEWEEQREERKKSMELTPP
Protein: Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Oxidized protein hydrolase) (OPH) (Q84LM4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. Can degrade the glycated RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) protein but not the native protein. May be involved in the elimination of glycated proteins. Plays a homeostatic role in sustaining the cytoplasmic antioxidative system. May contribute to the elimination of the oxidized proteins in the cytoplasm.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22398639}. Nucleus {ECO:0000269|PubMed:22398639}.
Interaction partners:
- Prolyl endopeptidase
- Prolyl endopeptidase
- Prolyl endopeptidase
- Probable carboxylesterase 12
- Cystathionine beta-lyase, chloroplastic
- Cystathionine gamma-synthase 1, chloroplastic
- Methylesterase 3
- Alpha/beta-Hydrolases superfamily protein
- Intermediate cleaving peptidase 55, mitochondrial
- Alpha/beta hydrolase domain-containing protein WAV2
Sequence:
MDSSGTDSAKELHVGLDPTTEEEYATQSKLLQEFINIPSIDKAWIFNSDSGSQAMFALSQANLLANKKKKFMLSGHISNESNQSVNFHWAPFPIEMTGASAFVPSPSGLKLLVIRNPENESPTKFEIWNSSQLEKEFHIPQKVHGSVYVDGWFEGISWDSDETHVAYVAEEPSRPKPTFDHLGYYKKENSLDKGIGSWKGEGDWEEEWGEAYAGKRQPALFVINVDSGEVEPIKGIPRSISVGQVVWSPNSNGSAQYLVFAGWLGDKRKFGIKYCYNRPCAIYAIKFTSDEPKDDDANEFPIHNLTKSISSGFCPRFSKDGKFLVFVSAKTAVDSGAHWATESLHRIDWPSDGKLPESTNIVDVIQVVNCPKDGCFPGLYVTGLLSDPWLSDGHSLMLSTYWRSCRVILSVNLLSGEVSRASPSDSDYSWNALALDGDSIVAVSSSPVSVPEIKYGKKGLDSAGKPSWLWSNIQSPIRYSEKVMAGLSSLQFKILKVPISDVSEGLAEGAKNPIEAIYVSSSKSKENGKCDPLIAVLHGGPHSVSPCSFSRTMAYLSSIGYSQLIINYRGSLGYGEDALQSLPGKVGSQDVKDCLLAVDHAIEMGIADPSRITVLGGSHGGFLTTHLIGQAPDKFVAAAARNPVCNMASMVGITDIPDWCFFEAYGDQSHYTEAPSAEDLSRFHQMSPISHISKVKTPTLFLLGTKDLRVPISNGFQYVRALKEKGVEVKVLVFPNDNHPLDRPQTDYESFLNIAVWFNKYCKL
Protein: WSC domain protein, putative (Q4WWU1)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- ER membrane protein Wsc4, putative
Sequence:
MSRKILHLAFLSLISLTPHVLASKDSSACYNSPGDLTLAESSEFMSRGMCEAKCEKNAVLAVQGTDCYCGSSIPSSSAKVSDDKCDTLCPGYAVDYCGGSKTWTIMYDTRLLKEDSDDSTSTSLTVNPTLVATITKDSANPTATIPAEILTAPSATFTKHPGVAQDMPSVNVTSSAAAAASKSAGTSSASASASSSTPSASPSGSAGSGASLSRSVGAAGPIIGAVFIPLVMSWF
Protein: Pyruvate kinase (Q8JGL9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
SNDPTEVTAIGAVESSFKCCAGAVIVLTTTGRSAQLLSRYRPRCPIVAVTRSPQVARQAQLLRGVFPVLFHPLPAPVWADDVDNRVNFGMNIGKARGFFKTGDMVIVVTGWIPGSGHTNIMRAVHVP