wanglab/gogpt-training-data huggingface dataset:
Protein: Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (Q1JU68)
Organism: Rattus norvegicus (Rat)
Function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03000}.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit M
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit J
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 3 subunit D
- Eukaryotic translation initiation factor 5
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 3 subunit F
- Eukaryotic translation initiation factor 3 subunit L
Sequence:
MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEEKTEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVAQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYIKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRVKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERKITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGEDPLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRETRDDERPHRRDEDRLRRLGGDDEERESSLRPDDDRIPRRGLDDDRGPRRGPDEDRFSRRGTDDDRPSWRNADDDRPPRRIGDDDRGSWRHTDDDRPPRRGLDDDRPPRRGLDDERGSWRTAEEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGMDDDRGPRRGLDDDRGPWRNAAEDRISRRGADDDRGPWRNMDDDRVPRRGDDARPGPWRPFVKPGGWREKEKAREESWGPPRESRPPEEREWDRDKEKDRDNQDREENDKDLERDRDRERDGDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRDRDDRRDLRDLRDRRDLRDDRDRRGPPLRSEREEASSWRRTDDRKDDRTEERDPPRRVPPPTLSRERERERDREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR
Protein: Citronellyl-CoA dehydrogenase involved in catabolism of citronellol (Q9HZV8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Geranyl-CoA carboxylase, beta-subunit
- Biotin carboxylase
- Isohexenylglutaconyl-CoA hydratase
- Peroxisomal trans-2-enoyl-CoA reductase
- Very-long chain acyl-CoA synthetase
- Expressed protein with apparent function in citronellol catabolism
- Short chain dehydrogenase involved in catabolism of citronellol
- Repressor of atu genes
- Electron transfer flavoprotein subunit alpha
- Probable acyl-CoA dehydrogenase
Sequence:
MIFTQEHEELRRTVRSFVEREINPNVDQWEKDGRFPIHEIFRKAGELGLLGISKPEKFGGMGLDYSYSIVAAEEFGSITCGGIPMAIGVQTDMCTPALARFGSDELREEFLRPAIAGEMVGCIGVSEVGAGSDVAGLKTTARKDGDDYVINGSKMWITNSPSADFMCLLANTSDDKPHVNKSLIVVPMKTPGITLSPHLDKLGMRSSETAQVFFDNVRVPQRNRIGAEGAGFMMQMLQFQEERLFGAANMIKGLEHCIDVTIEYCKERRTFGQPLIDNQVIHFRMAEMMTEVEALRALVYQATELYVKGRDVTRLASMAKLKAGRLGREVSDACLQYWGGMGFMWDNPVSRAYRDTRLVSIGGGADEIMLGIICKLMGILPGKKKG
Protein: Liver-expressed antimicrobial peptide 2 (Q6QLQ6)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MHCLKIMAFLLFFSLLLSQVYCASLHQPQPLLRLKRMTPFWRGVSLRPVGASCRDNSECITMLCRKNRCFLRTASE
Protein: Cilia- and flagella-associated protein 206 (Q8IYR0)
Organism: Homo sapiens (Human)
Function: Essential for sperm motility and is involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract (By similarity). Required for the establishment of radial spokes in sperm flagella (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q6PE87}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q6PE87}.
Interaction partners:
- Radial spoke head protein 4 homolog A
- Cilia- and flagella-associated protein 263
Sequence:
MPPTQAESVIRSIIREIGQECAAHGEIVSETLIAFMVKAVVLDPSNGFNMDRTLMKSDVQNLVKLCMTRLLDTKNPSLDTIKMQVYFDMNYTNRVEFLEEHHRVLESRLGSVTREITDNRACAKEELESLYRKIISYVLLRSGLGSPTDIKTVREVTAALQSVFPQAELGTFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAVLHVAIPATMQHIDYQLETARSQVYRYTAILEKAANDPLMRAELQPYMLKEALYNIRQYEVFLQIILSDIITGAQEVEMMTKQLGAHLEQLKMTIKSKIAVPTSQVFPIFIALSTLWTSLQDETIVVGVLSNLFTHIQPFLGAHELYFPERVMQCHLNGATVKTDVCRMKEHMEDRVNVADFRKLEWLFPETTANFDKLLIQYRGFCAYTFAATDGLLLPGNPAIGILKYKEKYYTFNSKDAAYSFAENPEHYIDIVREKAKKNTELIQLLELHQQFETFIPYSQMRDADKHYIKPITKCESSTQTNTHILPPTIVRSYEWNEWELRRKAIKLANLRQKVTHSVQTDLSHLRRENCSQVYPPKDTSTQSMREDSTGVPRPQIYLAGLRGGKSEITDEVKVNLTRDVDET
Protein: Large ribosomal subunit protein uL22 (60S ribosomal protein L17) (Q9W3W8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ubiquitin-ribosomal protein eS31 fusion protein
- Large ribosomal subunit protein eL15
- Small ribosomal subunit protein eS28
- Large ribosomal subunit protein eL34
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein eL38
Sequence:
MGRYSRESDNVAKSCKARGPNLRVHFKNTHETAQAIKRMPLRRAQRYLKAVIDQKECVPFRRFNGGVGRCAQAKQWKTTQGRWPKKSAEFLLQLLRNAEANADCKGLDADRLVVHHIQVNRAQCLRRRTYRAHGRINPYMSSPCHVEVILTEKEELVSKATDDEPAKKKLSKKKLQRQKEKMLRSE
Protein: Serpentine Receptor, class T (Q21785)
Organism: Caenorhabditis elegans
Interaction partners:
- Serpentine receptor class r-10
- Seven TM Receptor
- Serpentine receptor class r-10
- Serpentine Receptor, class D
- G_PROTEIN_RECEP_F1_2 domain-containing protein
- Serpentine Receptor, class AB
Sequence:
MSVYGFNPIDNLPEYYNFAYSFNILTIFTIVTATYTIFSFGVTLKMCIFYLKNRNSDVLKSGLRADVFRIFLLMQLWNAFHVLLDFLVVRIPLTSIFTSYCSLYKPEVALKILTLLFTGCVYTSHLLTLAFCVQRVALLYADEYQKDIISKVFDIVCPILIVFGHSLGIPHLLLTTSCFQMGIPYPFGSIVITASRMDMPVYAIIYAISTNAMIVLIVVTTIFMFAKLHQKRKLSAELHRTYNSKSEKVLTATMIFIILPIVMPAILSIVDIFAYGLYPYIFLFRCICLDARAHIVSCYFYFTHQIFKKKQLNRVECESGQK
Protein: 2S seed storage protein 5 (Seed storage albumin 5) [Cleaved into: 2S seed storage protein 5 small subunit; 2S seed storage protein 5 large subunit (2S albumin isoform 5 large subunit)] (Q9FH31)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This is a 2S seed storage protein.
Interaction partners:
- 12S seed storage protein CRB
- 12S seed storage protein CRC
- Vicilin-like seed storage protein At2g28490
- 12S seed storage protein CRA1
- Oleosin 18.5 kDa
- 12S seed storage protein CRD
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Proline-rich extensin-like protein EPR1
- Late embryogenesis abundant protein M17
Sequence:
MAKLILVFATLALFILLANASIYRTVVEFEEDDDVSNPQQGKCQREFMKHQQLRGCKQWIRKRAQQGRIGYEADDFELTLDVDLEDDENPMGPQQQSSLKMCCNELRQVDKMCVCPTLKKAAQQVRFQGMHGQQQVQHVFQTAKNLPNVCKIPTVGSCQFKASPY
Protein: Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8) (Q8R4D5)
Organism: Mus musculus (Mouse)
Function: Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17015441}; Multi-pass membrane protein {ECO:0000269|PubMed:35662242}. Membrane raft {ECO:0000269|PubMed:19176480}. Note=Lipid raft association modulates TRPM8 channel activity. {ECO:0000269|PubMed:19176480}.
Interaction partners:
- Transient receptor potential cation channel subfamily V member 1
- Transient receptor potential cation channel subfamily A member 1
- Transient receptor potential cation channel subfamily V member 2
- Transient receptor potential cation channel subfamily V member 3
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- ADP-ribose pyrophosphatase, mitochondrial
- Transient receptor potential cation channel subfamily V member 4
- G-protein coupled receptor 55
Sequence:
MSFEGARLSMRSRRNGTMGSTRTLYSSVSRSTDVSYSDSDLVNFIQANFKKRECVFFTRDSKAMENICKCGYAQSQHIEGTQINQNEKWNYKKHTKEFPTDAFGDIQFETLGKKGKYLRLSCDTDSETLYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRNSEENIVAIGIAAWGMVSNRDTLIRSCDDEGHFSAQYIMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKAINTSVKSKIPCVVVEGSGQIADVIASLVEVEDVLTSSMVKEKLVRFLPRTVSRLPEEEIESWIKWLKEILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQDKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRRSFWKEDRSSREDLDVELHDASLTTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGLVSFRKKPIDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQEYCNRLNIPFPFVVFAYFYMVVKKCFKCCCKEKNMESNACCFRNEDNETLAWEGVMKENYLVKINTKANDNSEEMRHRFRQLDSKLNDLKSLLKEIANNIK
Protein: Guanine nucleotide-binding protein subunit beta-like protein (Q57TT4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Autophagocytosis associated protein, putative
- Atg6 BARA domain-containing protein
- phosphatidylinositol 3-kinase
- Protein kinase, putative
- Ubiquitin-like modifier-activating enzyme ATG7
- Protein kinase, putative
- non-specific serine/threonine protein kinase
Sequence:
MVTMRMESSKDEEEEVSIRLGARLAARYAPNQILTSTQSWGSLMGVEQFRRLFQCFSKYSISDDGDPALTNEWTIHFVVGIIDARLNVANCSGDPDEDVNMDLTLTMSYDSNWKEYIKEVEEWVNSLSIRLDVHDALWDACELSNKELLKLLLNDSKESRSGSLHSQDEEDEHSSEGSESATIMRVRRKGRHTQMVEQASAGLIELLQKKTRTHSLVRWSDITNNFVRDYEHSHDFGDETISYTQICDKVSSGRYSKDSRKDNEGWPDWARARKDKKRDGKALWKYEIHLQSPDHVLVAPLSAFIITSSKDGFVKVWSAATGAFVRNLFNTGSSWVIGMYLLMDEDYILISTTNNQLTLLDFSSGDIIQKYVGCESLLTACNEVNQPSAQDVQRYGMRPGECGLYRIRLRENEQSIMFHRRRRDAQKDVLPKKVLAKPVVGFLNPTATWFEPHLGMFCFGTAEGKVGAFDVSADVRASALLSGANTKPVRLEFLVTMHKEMVSGLFYSSYATSIFTAGADGFVYRLPVGPSFEPAGEPRRIGHQMRAIRSMEWIPPSKYFITVHVNRRVSVWVIGRHGDPFRSFPPESQEILSASMHPHRGRLAVLLADKTIKVYEVHASKSIATIQQPEPQSNFTASDFSRQMMERSERDSDGVVAWHPFHSTLICALRGPVLYAASKSKDSSSSASRTRRQRCEGATAQSTGAEFGNMVEEDDGEVAEHRGAAVRDSRQPCSHSGGVVAAVIHKASLMVHTFDEGTWRAWKLTTGEMKRHVVVSHAVRMGDISRSHATVASCSWSTSSQVRLVTGGQDCSLITWDPETYAPLESEMLVQDASDQLDSDVFTFSHQSKLIAWAARTCRVTTYSRKVLPSGVEESKSVVFRVPGLTSITACCVARDTYLCIGTGDGTLYVYSIGGGHPIAECRLGEQSEARRSAVLQLAYVNEQGQNLIVAVLDTGVLCIYSFVTQTVISHLRLIRRFDCLIRKALFISDDGLMIYGDSRGRVCGFDLHAVTTPVAELQQFVVRRFAFSGASDEVTTLEVFSFQGHRFIIVGSLDRQVRLFRIEDALRKPSLSNSGLQPAGWSFNKVLLVGVFGRDRWDLEDVTTYAGEPSFVEGKQNCNTMEEVLVESIMKPENSFQSIMNVGAAAAEDGASVPLSRGKRVSVVATTIMPPGTPSVPSFFLTEATAVQGDVACPTTPSSSIQDSMEQLAGQPTCPQTVPVISEGASCSGAPLGSEQTALPQGQTRRSHSHPRSRAASSTTSSAGDESPTNAGNHSLGCSSALELRGSLSGKGSARSHFSSEVHDASRAKAVLVSLTSRLDKVRPYGYARGAFRRKLQGLLPGDGDLSMELDQQALGPSTSSTLRLALETRRRLSERMDEYKRRQEEMKKRRKFDYSSCFARSVLPPVVIPKPSMISPDLMPTSDWMVDGMRKQTQLQPSVTASTVGRTV
Protein: Rad9 (Q76F79)
Organism: Gallus gallus (Chicken)
Interaction partners:
- Checkpoint protein
- DNA topoisomerase II binding protein 1
- Uncharacterized protein.
- Cell cycle checkpoint protein RAD1
- Replication factor C subunit 2
- Uncharacterized protein.
- ATR serine/threonine kinase
- Non-specific serine/threonine protein kinase.
- Uncharacterized protein.
- Replication factor C subunit 4
Sequence:
MKCVIEGGNVKALGHAVHALSRVGDHLYLEPSDAGLSLRAASTSRSAFASFLFVPLFFQRYEPGPPGTRCKVLMKSFLGVFRSLPTLDKSVERCLVLLRPRAGRLVLQLHCKHGVTRTHQLAFQECERLQAVFDTQCCASRLRAPAQLLAEAVVHFPQTLAEVTLGAAAGGRIGLRSHLEEGSEPGKAMVTELWLAPDEFQEVAVVPGSRITFCLKEFRGLLSFAEASSLPLTIHYDEPGRPAIFTLDDSLMEAHLVLATLLDPESDSQPPPATNGRVSHPPAPPDDFADDLESYMVALESSACEGEAGAPPSPNFSLHTPRPAESDPEEEEDGAVPGTPPHKKFRSLFFGSVLTPGGPGPAPSQEVLAEDSDAEC
Protein: Large ribosomal subunit protein uL29A (60S ribosomal protein L35-A) (P0CX84)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Ribosome biogenesis protein RLP24
- Nucleolar GTP-binding protein 1
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL27B
- Ribosome assembly factor MRT4
- Large ribosomal subunit protein uL24A
- Large ribosomal subunit protein uL24B
- Ribosome biogenesis protein NSA2
- Small ribosomal subunit protein uS7
Sequence:
MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA
Protein: Monopolar spindle 1, isoform B (EC 2.7.11.1, EC 2.7.12.1) (A0A0B4KG66)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Mitotic spindle assembly checkpoint protein MAD2A
- Kinetochore protein NDC80
- Spc105-related, isoform B
- Bub1-related kinase
- Serine/threonine-protein kinase polo
- separase
- Mitotic checkpoint protein BUB3
- Bub1 kinase, isoform A
- RE25723p
- Rough deal
Sequence:
MTTPVPRRTKDMMALGLDSDSEDDFNTPYRPRQAAAGERKQQPVASFQVQTRGKENEPHPLPINMLPRRVSELTMMDSDSDEEDIKSNHNLNCAILNDSFVLSPSQELTNSNSNITTRRTPSAAPLKQSDSNLSFLGRFNDMGINCSSQGSPVANSEKQVAKKTAPTLQAAPSATERRPLQETETPLRNELPSTSKTKPDADFITPQVRTIGSTLAGKSRSAVSNDFRAQKVLFQTPMTVSRAAPVASDSISFSLCDTITESPDIPEPPKKAEPPKSQHPSKKSLDHVFRESDKDNVPDKVDNVEPKELVSIPAVAVPPEQPSHKTSNILKIKNHEYTIDKKLGCGGSSSVFLARRSDSGNEFALKVVDLQADPQVVQGYLNETKLLAKLQGNVCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTNLPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLKLIDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYPAIPPYYPIMLVHFTTVSALFADGQELPTVESQKAAVVHRTTTVPIPYDHSAAEPADTQQNRQQQLSTKAQLFISEMSKVKCLSHMCVYIFNSHFIVN
Protein: Protein Largen (Proline-rich protein 16) (A3KMN5)
Organism: Mus musculus (Mouse)
Function: Regulator of cell size that promotes cell size increase independently of mTOR and Hippo signaling pathways. Acts by stimulating the translation of specific mRNAs, including those encoding proteins affecting mitochondrial functions. Increases mitochondrial mass and respiration (Probable).
Interaction partners:
Sequence:
MSAKSKGNPSSSSAAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKEQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVRCEEPQRVVPTANPVKTNGTLLRNGGLAGRPNKIPNGDICCIPNSNLDKAPLQSLMHRPEKDRSPQAGPRERVRFNEKVQYHGYCPDCESRYNIKNREVHLHSEPVHPPGKIPHQGPLLHPPPHLPNFPLENGGLGISHSNSFPPPTPATVPPPAAPKPQKTILRKSTTTTV
Protein: Glycine N-acyltransferase-like protein (EC 2.3.1.13) (Acyl-CoA:glycine N-acyltransferase-like) (AAc-like) (Q5FW57)
Organism: Mus musculus (Mouse)
Function: Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- CEA cell adhesion moleculen23
- Olfactory receptor
Sequence:
MLHLRSSQMLQMLESSLRKYLPESLKVYGTVFHMNQGNPFKLKALVDKWPDFNTVVVRPREQEMGDDLDQHTNTYQIYSKDPKHCLEFLGTPDVINWKQHLQIQSSQSNLNEAIMDLAAGKMVKVKRTQCILYMMPETAKKLVPSLLEDKEYLDHQSGRPRAIDQEMFKLSTLDVTHAPLVDKFWQFGGNERSQRFIGRCIQIFPSSCLLGPEGTPVSWALMDQTGEIRMAGTVPDYRAQGLISHIIYAQTLAMDKRGYPVYNHTEQTNKVIQKMSHTLHHVPMPCDWNQWYCAPL
Protein: Phospholipid/glycerol acyltransferase domain-containing protein (Q9N5S8)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Probable glycerol-3-phosphate acyltransferase, mitochondrial
- Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2
- Probable glycerol-3-phosphate dehydrogenase 2
- Phospholipid/glycerol acyltransferase domain-containing protein
- Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
- Glycerol-3-phosphate dehydrogenase [NAD
- Probable glycerol kinase
- Probable glycerol-3-phosphate dehydrogenase, mitochondrial
- Phospholipid/glycerol acyltransferase domain-containing protein
- Uncharacterized protein F52C9.3
Sequence:
MLGIEHLLFVLTTFAFPPVALTVLLCIILATFGKSLGLRQMYVDTLINIFEWGARQIKTTEKIRRKESALTAPFFLNKLSEEADDDEDEIRSMETPHFEATDGITDDEIEARSETESHDSGEDFPSVDSDFGDESCLKRKFGSTTSLASVGSCCSLRNRKMSESSTLGIIKRETQIYLDDNFSEDIPDEVFVRSRGWAAIRDSVDFVKAGMEAIIEDEVTSRFEAEQLVSWNMLTRTSIKFYQFVNWKLSALWILGFMFRYCVMLPLRFTVFCIGLVFLISSTALIGLVPIGNWKKALNHKCMLICYRILSRSLTAVVYFHDEHYKAQAQGICVANHTSPIDALILSIDNVYALIGQKHEGLLGIVQRALSRASSHIWFERSEAKDRLVVAQKLKEHCTNPDKLPILIFPEGTCINNTSVMMFKKGSFEIGTTIYPIAMKYDSRFGDAFWNSSEQSWCGYIMRMMTSWAIICNVWYLPPMTRRDGEDAVDFANRVKKEIANKGGLVDLEWDGGLKRAKVPPKMVAKQQERYANRLSRYTSVSEVVKDEDVDVTSDYLVDKPVSGYNSLEDLPEDVFIDEEEDETIDAHDENENDDPAGESNILPNKPLSDTVSLVKT
Protein: Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2) (P29034)
Organism: Homo sapiens (Human)
Function: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.
Interaction partners:
- Cellular tumor antigen p53
- Protein S100-A1
- Protein S100-B
- Protein S100-A3
- Hornerin
- Protein S100-A7
Sequence:
MMCSSLEQALAVLVTTFHKYSCQEGDKFKLSKGEMKELLHKELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEYAVFLALITVMCNDFFQGCPDRP
Protein: Quinolinate synthase (EC 2.5.1.72) (Quinolinate synthetase A) (P11458)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00567, ECO:0000305}.
Interaction partners:
- L-aspartate oxidase
- Nicotinate-nucleotide pyrophosphorylase [carboxylating]
- Nicotinamide riboside transporter PnuC
- Trifunctional NAD biosynthesis/regulator protein NadR
- Nicotinate phosphoribosyltransferase
- Nicotinate-nucleotide adenylyltransferase
- NH
- 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
- Nicotinamidase
Sequence:
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
Protein: RRN3 homolog, RNA polymerase I transcription factor (H3BMT1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAPLLHTRLPGDAAASSSAVKKLGASRTGISNMRALENDFFNSPPRKTVRFGGTVTEVLLKYKKGETNDFELLKNQLLDPDIKDDQIINWLLEFRSSIMYLTKDFEQLISIILRLPWLNRSQTVVEEYLAFLGNLVSAQTVFLRPCLSMIASHFVPPRVIIKEGDVDVSDSDDEDDNLPANFDTCHRALQIIARYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNLLRISVYFPTLRHEILELIIEKLLKLDVNASRQGIEDAEETATQTCGGTDSTEGLFNMDEDEETEHETKAGPERLDQMVHPVAERLDILMSLVLSYMKDVCYVDGKVDNGKTKDLYRDLINIFDKLLLPTHASCHVQFFMFYLCSFKLGFAEAFLEHLWKKLQDPSNPAIIRQAAGNYIGSFLARAKFIPLITVKSCLDLLVNWLHIYLNNQDSGTKAFCDVALHGPFYSACQAVFYTFVFRHKQLLSGNLKEGLQYLQSLNFERIVMSQLNPLKICLPSVVNFFAAITNKYQLVFCYTIIERNNRQMLPVIRSTAGGDSVQICTNPLDTFFPFDPCVLKRSKKFIDPIYQVWEDMSAEELQEFKKPMKKDIVEDEDDDFLKGEVPQNDTVIGITPSSFDTHFRSPSSSF
Protein: Multiple antibiotic resistance protein MarR (P27245)
Organism: Escherichia coli (strain K12)
Function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.
Interaction partners:
- Multiple antibiotic resistance protein MarA
- Multiple antibiotic resistance protein MarB
- Transcriptional regulator SlyA
- Redox-sensitive transcriptional activator SoxR
- HTH-type transcriptional regulator AcrR
- Regulatory protein SoxS
- DNA gyrase subunit A
- Transcriptional repressor MprA
- Regulatory protein AsnC
- Arabinose operon regulatory protein
Sequence:
MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP
Protein: Uncharacterized protein (Q558Y3)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Polycystin cation channel PKD1/PKD2 domain-containing protein
- Mechanosensitive ion channel MscS domain-containing protein
- MRH domain-containing protein
Sequence:
MNTLKRTVFSQRLEAVKALENKTREEKATLLAAVETQRNARLVKDLIIHLVFFVVFVLIVVLQLNPQSLFIINTSLKNQILFSQDSQYLEINNPSDFITYLNSTFCESISDMSLENNDAMNKIIGNVIRIRTARVKPDSCSNNGFNLTCYSNNYDKDTKDRSPFGPNDMYTYTSNSHGSYVFGHNQYVWDRSGYYIDIPVSDIKTGVESLIDNGFFDIQTRSVIISFSTLNLNFQSRTSVFTMLTEWTASGSVNPYYSIRTYRIQLYMDALDKFRGFLEVSFFIFILYYFYYFVNEARIDFKLGRFKFYISNFKNIFDVINLTLFIASIALYLAFLGDNSRDLNINSQIQTTTDYPLYLENLGQTALVLYQISAINILLMSFKTFRFLVVHRRLYILWIAISQSRLQLITFTIMFCIMMLGFLFSGWLTFGTDIASFNGFVTSLGTLLQFIIGNPPDYEAMSYTNRALGPIYYLLFTIFMFFILVNMFVAIISDSYQNISNTFEKKQKTKRYLLTRWERTMKSLLLLFTPNSLDIYDLVLMFIDQKPGLIETDGIDPSRFKDEIMIIQPIQRARIKYLDQIQSAKNTGVTFELKLMGQQVHKKDLDTWKKEAKIKEKKKFESIQQNINILNTKLDLLLQAMNVPQQSIPQLINGSTGMPQSPIINNNNNNGGSIPSSSSNGSINGSNHINLSGGTNTP