wanglab/gogpt-training-data huggingface dataset:
Protein: Chloride intracellular channel protein 1 (Chloride channel ABP) (Glutaredoxin-like oxidoreductase CLIC1) (EC 1.8.-.-) (Glutathione-dependent dehydroascorbate reductase CLIC1) (EC 1.8.5.1) (Nuclear chloride ion channel 27) (NCC27) (Regulatory nuclear chloride ion channel protein) (hRNCC) (O00299)
Organism: Homo sapiens (Human)
Function: Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.
Subcellular location: Nucleus {ECO:0000269|PubMed:12681486, ECO:0000269|PubMed:9139710}. Nucleus membrane {ECO:0000269|PubMed:9139710}; Single-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:10793131, ECO:0000269|PubMed:11551966, ECO:0000269|PubMed:12681486, ECO:0000269|PubMed:9139710, ECO:0000305|PubMed:11978800, ECO:0000305|PubMed:14613939}. Cell membrane {ECO:0000269|PubMed:11551966, ECO:0000269|PubMed:11940526, ECO:0000269|PubMed:14613939, ECO:0000305|PubMed:11978800}; Single-pass membrane protein {ECO:0000269|PubMed:11551966, ECO:0000269|PubMed:14613939}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q6MG61}. Note=Mostly in the nucleus including in the nuclear membrane (PubMed:12681486, PubMed:9139710). Small amount in the cytoplasm and the plasma membrane (PubMed:9139710). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (PubMed:11551966, PubMed:11940526, PubMed:12681486, PubMed:14613939, PubMed:9139710). Might not be present in the nucleus of cardiac cells (By similarity). {ECO:0000250|UniProtKB:Q6MG61, ECO:0000269|PubMed:11551966, ECO:0000269|PubMed:11940526, ECO:0000269|PubMed:12681486, ECO:0000269|PubMed:14613939, ECO:0000269|PubMed:9139710}.
Interaction partners:
- Mitogen-activated protein kinase 15
- Polyhomeotic-like protein 3
- Ezrin
- Annexin A2
Sequence:
MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK
Protein: Leucine-rich repeat-containing protein let-4 (Lethal protein 4) (Q93373)
Organism: Caenorhabditis elegans
Function: Required for apical extracellular matrix organization and epithelial junction maintenance.
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:22278925}; Single-pass type I membrane protein {ECO:0000269|PubMed:22278925}. Note=In the excretory canal cell at the 1.5-fold embryonic stage, localized uniformly at the cell membrane. {ECO:0000255, ECO:0000269|PubMed:22278925}.
Interaction partners:
- WaRThog
- Leucine-rich repeat-containing protein let-4
- NOmpA Homolog
- LiPocalin-Related protein
- Protein let-653
- PAN domain protein
- EGF-like domain-containing protein
- LiPocalin-Related protein
- LiPocalin-Related protein
- Transmembrane cell adhesion receptor mua-3
Sequence:
MRLLLCLLLFSTLLINSTNACPGVITQACFCSEVHSGIVLDCSNSSASGILQIIRTNQAQVGLIQSLTMNQAELVELPPNFFSGLFIRRLDLSQNKIKKIDDAAFAGINPVLEEVVLNHNLIEKVPAAALAGLPNLLRLDLSNNSIVEIQEQEIFPNLNKLYDINLGSNKIFSIHTSTFQNVKNSIQTINLGHNNMTAVPSSAIRGLKQLQSLHLHKNRIEQLDALNFLNLPVLNLLNLAGNQIHELNRQAFLNVPSLRYLYLSGNKITKLTAYQFQTFEQLEMLDLTNNEIGAIPANSLSGLKQLRQLYLAHNKISNISSNAFTNSSIVVLVLSSNELKTLTAGIISGLPNLQQVSFRDNQIKTINRNAFYDAASLVMLDLAKNQLTEIAPTTFLAQLNLLLVDLSENKLPKTPYSAFNSRVGTVLLKENPLVCTENLHMLQQGTGVYVRDSPDIICGRKPTPKPEPVLVPIVTDSLISTQRPALVQIPKMQIHRNVHTTTGDQAPQIPSGAFQQIDLGKSRSLPRGHSRFILDKPSTREQSVEPTEELTPIQPIILPSREDEIRQSSMEAGTSQESVEATSQKIPSTTDIIDRPNVVLPFPVPFLKRGPNLSESKKVESTDMPSTSQVFHTLPPSILIEPGSTPKVAQPSTEANIKSEHIDEFALASSNSNEPTLQPRLEKSFFTTTIIFICVGTAVIVLVVVIAGLCISKHRQLQFENTYSDSSAARTSEYISTQYRQNSLRGTGGRVGRFEESPAWIYNPGSSYCNYYK
Protein: UPF0481 protein At3g47200 (Q9SD53)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Pre-mRNA-processing factor 39-2
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- Protein STRUBBELIG-RECEPTOR FAMILY 5
- At3g57220
- DEAD-box ATP-dependent RNA helicase 10
- Tyrosine-sulfated glycopeptide receptor 1
- ABC transporter C family member 10
- Putative nuclear RNA export factor SDE5
- Transcription termination factor MTERF15, mitochondrial
Sequence:
MADKTDIISSSSDKASPPPPSAFRNYLSSGSKEPVLLLESAGKESCCIFRVPESFVALNPKAYKPKVVSIGPYHYGEKHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHDLMFMMVLDGCFILMVFLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNPIDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQFYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDKKGNGNAAPPPLGLP
Protein: Uncharacterized protein Rv2560 (P9WLA1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized AAA domain-containing protein Rv2559c
Sequence:
MSQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYGPPPGPPPPGYPTHLQSSGFSVGDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGLVVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYIALFALVLYMHAGILTGCLDIADGKPVTIATFFRPRNLGLVLVTGLLIVAVTFIGGLLCVIPGLIFGFVAQFAVAFAVDRSTSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPPGPQLA
Protein: F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A) (Q9UKT7)
Organism: Homo sapiens (Human)
Function: Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:10531035}. Cytoplasm {ECO:0000269|PubMed:10531035}. Note=Predominantly nuclear.
Interaction partners:
- Cryptochrome-2
- Cryptochrome-1
- S-phase kinase-associated protein 1
- Cullin-1
- Circadian locomoter output cycles protein kaput
- Basic helix-loop-helix ARNT-like protein 1
- Period circadian protein homolog 2
- Casein kinase I isoform epsilon
- Casein kinase I isoform delta
- Neuronal PAS domain-containing protein 2
Sequence:
MKRGGRDSDRNSSEEGTAEKSKKLRTTNEHSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW
Protein: T. brucei spp.-specific protein (Q38ER1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHKQGLTYKYGNEPRVFPERRKRERPPPFQPLDPQRDLAATAEIKSAAQTLMAVPPDCYGAQHSSVKRPAYEHRRESFRRSGHRRSQTETEQLSVEQRNFTSRQQNEGCSTQDVEDGAVKTTTHQPEVPPMEAKPPEPSPLQELLRRIIIFEFSSKCTQRSINVVRTICDTLCKNPAGVVEAMLVIEGCFADALKERNQQRLLHYWYIVDAIMKLFRDRQLMLEAVFVALPHLLLVYVPWNNSKLAMEPWFNREKDTENYKNLFNVWESIVPEKITNDIKKLWQDGFPVGIH
Protein: C-X-C chemokine receptor type 2 (High affinity interleukin-8 receptor B) (Q53PC4)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
Protein: Flotillin (Q6IB58)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Membrane, caveola {ECO:0000256|ARBA:ARBA00004543}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004543}. Membrane {ECO:0000256|RuleBase:RU366054}. Endosome {ECO:0000256|RuleBase:RU366054}.
Interaction partners:
Sequence:
MFFTCGPNEAMVVSGFCRSPPVIVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVNHKPLRTA
Protein: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase) (P11507)
Organism: Rattus norvegicus (Rat)
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Involved in autophagy in response to starvation. Upon interaction with VMP1 and activation, controls ER-isolation membrane contacts for autophagosome formation. Also modulates ER contacts with lipid droplets, mitochondria and endosomes.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O55143}; Multi-pass membrane protein {ECO:0000255}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:O55143}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with FLVCR2 at the mitochondrial-ER contact junction. {ECO:0000250|UniProtKB:O55143}.
Interaction partners:
- Phospholamban
- Histidine rich calcium binding protein
- Sarcolipin
- Calcium-transporting ATPase
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
- Histone acetyltransferase KAT5
- RAR-related orphan receptor A
- A-kinase anchor protein 7 isoforms delta and gamma
- Ryanodine receptor 2
- Calreticulin
Sequence:
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELSPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECAQPATKPSCSLSACTDGISWPFVLLIMPLVVWVYSTDTNFSDMFWS
Protein: Erythrocyte membrane protein band 4.1 like 1 (A0A0C4DH22)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANERAGLREGSEEKVKPPRPRAPESDTGDEDQDQERDTVFLKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYHGSAFEDFSRSLPELDRDKSDSDTEGLLFSRDLNKGAPSQDDESGGIEDSPDRGACSTPDMPQFEPVKTETMTVSSLAIRKKIEPEAVLQTRVSAMDNTQVDGSASVGREFIATTPSITTETISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYGATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES
Protein: Preprofallaxidin-6 [Cleaved into: Fallaxidin-1.3; Fallaxidin-1.4; Fallaxidin-3.1] (B5LUQ8)
Organism: Litoria fallax (Eastern dwarf tree frog) (Hylomantis fallax)
Function: Fallaxidin-1.3 shows no antibacterial activity against Gram-positive or Gram-negative bacteria. Does not inhibit the formation of NO by neuronal nitric oxide synthase. Has no effect on splenocyte proliferation or smooth muscle contraction.
Subcellular location: Secreted {ECO:0000269|PubMed:18803332}.
Interaction partners:
Sequence:
MASLKKSLFLVLFLGFVSLSICEEEKRENEGNENEEEDENHEEGSEEKRGLLDLAKHVIGIASKLGKRSEEKRYHPFGKRSEEKRYHPFGKRSEEKRYPPIGK
Protein: Regulator of chromosome condensation (Q383P6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFFWGSYNFFEPRQADPPNRPPLRYPVYVPPSLSMMADAGIAEPEKILKTEQDDIQSTLQHVDNHRIVVKLIGCGQKHLVGLMGLAPKSSMGSALPRREGAVTSDIGSNVTYALYGMGSNHSGQLGHRLPTYSTTLVKLQFEELLPPGVTVSSIACGDKYTVVSTSDGLAFAAGDNSFSQLGTVGKGLGFAPVRGIHNIKRVFAGGNATFALDGNGQLFSWGEAQYGHLCHGDNGQRLDVKTLKTVNTNVSVPTRIEWFVRRHVTIVDVSVSRSHVVCRSGDEVYTCGDGTYGKLCSGSFESSYLPVRVKFPERTHPERVCAIAAGDDHTLILRESSAVGAVVYYFGKAKNGDGQLIPDIISLPSNVQNIFAGRGTFSAATTSDGLLYVWGKQVYTGLSNGTSGKASRSYPCSVVALESHNITSVAAGATFVVATGGERRACEGIANEGERWDIVIPHDDRTESGYGDSFSSRYESAVQAFLTQYLGPSVAGAYISGIPEAPLATNPNANRFKPIGAHSLTVGQKVRLWMTDVYALASITKVFGRKEQSNHVDISGKTNEEERDHQQHLQIKNEEEEKENLGLSEVSGSADAPGYRFCIEWQRDDWRDEEVTLYSDDETLEETNPNRWQPLWFLYDETAGNYVVGK
Protein: Uncharacterized WD repeat-containing protein C4F8.11 (O14186)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Protein transport protein sec13
- Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05
- Nucleoporin seh1
- Uncharacterized WD repeat-containing protein C12G12.01c
- Nitrogen permease regulator 3-like protein
- Nitrogen permease regulator 2 homolog
- Vacuolar membrane-associated protein iml1
- GTP-binding protein gtr1
- GTP-binding protein gtr2
- Mitochondrial inner membrane protease subunit 1
Sequence:
MPSRNSNVLQRPTYAQLASTSVKSSKGLVSYQDWVVDVKASISAISVNKSRTKVGVAGRELLKVLAVNPNSSKPPVCISDLLQKSTQTKHISCNDVKWGSSFASNLIFTCSPLGNLNVWDVNLEALLYDFNEHSRAVHKLDISSFHPSYVLTASQDGLIKLWDYKESSSTITFRGNSEAARDVVFSPSEPNEFVAAYDSGILQKWDIRFPKLPFLKLAAHNGVVLCVNYSPNGVFLASCGRDKTIRIWDSTSNKKKSLITINNVSPLNCVRWRPANQQSRGSNQLASSSLVGDTAINVWDITRPYIPYRTVSCHDSIVSTMHWASTELLWSCSKDGIFSQTRVENAFNCIDMLPRATSSWSTKNSLVFSSNPISNQRLSSLNRVASFESNISSLKSALYASQNSDGSTSNPVPFVPHNFVGIPQELGILAYRSEDVAQFCYLAKNYRISGDISSACKENAFFARNVGAEFAYQIWDALYFSLGVLNNSDKGISELINIPFVSANNSMADDEKGRNLKNLTQISTSSTPAHDNLSLNDFFEPREASTPSESSNSSIESEDNLDKAVLNKQSQWHDLENPIVLKKGQAPVNNFSTDSRASINSSYLLDSAASNYSGTSHNEMFNSFHRSSVTSASIKSREAVLSAGNSSRRASIFLDQLSLHGDTDSEIPIDDLPPIELPYVVTSIISDCISRGDVQTAACVCSVFSYLTIDLPRIQLDDLLESYVDLLRRFGMFSEATLLINMSGSKNLKYIHSSSRDLIFEMENKKATGNEQSEKGKENAKTVTSLKKCVYCELPLRGVLVYPPVCGHIGHESCLRSWYFDNTDDALPVCPVPGCGVKLLDKRALI
Protein: Protein C10 (U3KQ07)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MASASTQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGGSDAGRRVRRGKAGVGSGEGAGSVGP
Protein: RE55923p (Q8IGP1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAALQRKLVHKQFNSPMGLYSQENVKATLNRELKAFGGEGIEVDDQITKPLNLANSAVLRAVEEEEQQAKCGYKRVAWPPASEERIIREFTPQPQTQSPAPGAGGYYPQAHAPTAAAAAPPQGPIYNNVQPRTTQTPQNAYPSAPQTTSTAYPTNQYPDSYSHQEQQQQQQQQQPVQYTQAQFGRQRSREPVQVSAPSPAPATDPSGYPYQANYQSNYPQEPLQAVNNVGGGWKHIGAPQPKSRSEFTAGNGAYPPFQGSYQQQQQQPQQQYGAPSYDGQQPGAQWQQQQQQQQVPQQQYQPQSQAQAPYQPPQWNQPQQQQQQPSYQASPYQQQQQQQPSYYPQQNGGSTYAQPPYNSYSQPQLPYSQDQTDLQQQQQQQQQQYPGAYAGQDSYRGASPGIITLRKEAPVSQKPAPVYTSQPAAVSYQGGSKLRGDLKWPPPEYKEAAARENEERRQLALGPVCRPRRVNRDYTPFFAKHQLNNGYPSYKVPPGTQHIFG
Protein: Cysteine/Histidine-rich C1 domain family protein (Q3E937)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGEIDKIRDGFLGAVKLAVHRHFLFPTNISSKCRVCSIERLEPTKVLTCNQCEFSLHEDCIEITSPSHHKHPLKLHERIIGYRRRDQCCLCRYKLLDMFYNCSRCMFEVCMACLKRPLLIYKTTSHKHPLSLMPIDSVSFTCDACGSVDNSSYPCTCLQCCFIIHRDCIDLPSVISINRHDHRISHVDILRPEEWICGVCHKIINNQYGAYSCSVCHYAVHSKCAIRDDVWDGKELDGIPEEEGDNKTEDITPFEVIDDKVIKHFSHEHILRFIYQDVLIRDENQRCYACVLPFYYDACYICTHCDFILHETCANLPRTKRHELHKNHFTLYPNPKPGEDLELSKSFFTCVACQRPSNGFRYESGNVKLDVRCATISDEFNHDSHLHSLFILSLFPRECSACDQMVYGSLSCVKLDFFLCFKCATLPKEVFNKNDKHPLYLRYSGYRYGNYWCEICEKPTDPRKWFYSCDKCCSTLHIDCVLGKSPYMRPGHSFLLCSREFQVVSNNHTSRPFCTICSLRCKDAFVLKSKDETDTSCLCSLKCLDSLVMSMQRIKL
Protein: Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2) (Stimulated by retinoic acid gene 7 protein) (P48031)
Organism: Mus musculus (Mouse)
Function: May act as a transcription factor for cell pluripotency and differentiation in the embryo.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Proto-oncogene Wnt-1
- Fibroblast growth factor 8
- Homeobox protein OTX2
Sequence:
MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPPPPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQEAAAARKFAPQPLPGGGNFDKAEALQADAEDGKAFLAKEGSLLAFSAAEAVQASLVGAVRGQGKDESKVEDDPKGKEESFSLESDVDYSSDDNLPGQTAHKEEDPGHALEETPQSGGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQARP
Protein: Transgelin (22 kDa actin-binding protein) (Protein WS3-10) (Smooth muscle protein 22-alpha) (SM22-alpha) (Q01995)
Organism: Homo sapiens (Human)
Function: Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Actin, aortic smooth muscle
- Myosin regulatory light polypeptide 9
- Myosin-11
- Myocardin
- Actin, gamma-enteric smooth muscle
- Serum response factor
- Smoothelin
- Caldesmon
- Collagen alpha-1
- Calponin-1
Sequence:
MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
Protein: Armadillo repeat-containing protein 8 (Q8IUR7)
Organism: Homo sapiens (Human)
Function: Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.
Subcellular location: Nucleus {ECO:0000269|PubMed:17467196}. Cytoplasm {ECO:0000269|PubMed:17467196}.
Interaction partners:
- Glucose-induced degradation protein 8 homolog
- Glucose-induced degradation protein 4 homolog
- E3 ubiquitin-protein transferase RMND5A
- WD repeat-containing protein 26
- Ran-binding protein 10
- Ran-binding protein 9
- E3 ubiquitin-protein transferase MAEA
- E3 ubiquitin-protein transferase RMND5B
- Muskelin
- Protein yippee-like 5
Sequence:
MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA
Protein: UDP-glycosyltransferase 74F2 (EC 2.4.1.-) (AtSGT1) (Salicylic acid glucosyltransferase 1) (O22822)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Glycosyltransferase that glucosylates benzoic acid and derivatives. Substrate preference is benzoic acid > salicylic acid (SA) > 3-hydroxybenzoic acid > 4-hydroxybenzoic acid. Catalyzes the formation of both SA 2-O-beta-D-glucoside (SAG) and SA glucose ester (SGE). Has high affinity for the tryptophan precursor anthranilate. Catalyzes the formation of anthranilate glucose ester. Is the major source of this activity in the plant.
Interaction partners:
- Salicylate/benzoate carboxyl methyltransferase
- Isochorismate synthase 1, chloroplastic
Sequence:
MEHKRGHVLAVPYPTQGHITPFRQFCKRLHFKGLKTTLALTTFVFNSINPDLSGPISIATISDGYDHGGFETADSIDDYLKDFKTSGSKTIADIIQKHQTSDNPITCIVYDAFLPWALDVAREFGLVATPFFTQPCAVNYVYYLSYINNGSLQLPIEELPFLELQDLPSFFSVSGSYPAYFEMVLQQFINFEKADFVLVNSFQELELHENELWSKACPVLTIGPTIPSIYLDQRIKSDTGYDLNLFESKDDSFCINWLDTRPQGSVVYVAFGSMAQLTNVQMEELASAVSNFSFLWVVRSSEEEKLPSGFLETVNKEKSLVLKWSPQLQVLSNKAIGCFLTHCGWNSTMEALTFGVPMVAMPQWTDQPMNAKYIQDVWKAGVRVKTEKESGIAKREEIEFSIKEVMEGERSKEMKKNVKKWRDLAVKSLNEGGSTDTNIDTFVSRVQSK
Protein: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 (Q9JMF3)
Organism: Mus musculus (Mouse)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
- Taste receptor type 1 member 2
- Taste receptor type 1 member 3
- Taste receptor type 1 member 1
- Guanine nucleotide-binding protein G
Sequence:
MEEWDVPQMKKEVESLKYQLAFKREMSSKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVEKAKCTIL
Protein: Rano class II histocompatibility antigen, B alpha chain (RT1 class II antigen, Ba chain) (P20037)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Rano class II histocompatibility antigen, D-1 beta chain
- Rano class II histocompatibility antigen, B-1 beta chain
- H-2 class II histocompatibility antigen gamma chain
- RT1 class II, DO beta
- T-cell surface glycoprotein CD4
- T-cell receptor alpha chain V region PHDS58-like.
- Histocompatibility 2, class II antigen E alpha
- MHC class Ib antigen
- Hla-dmb protein
- Major histocompatibility complex, class II, DM alpha
Sequence:
MPLSRALILGVLALTTMLSPCGGQDDIEADHVGSYGITVYQYHESKGQYTHEFDGDERFYVDLDKKETIWRIPEFGQLISFDPQGALRNIAIIKHNLEILMKRSNSTPAVNEVPEATVFSKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKPLTEGVYETSFLINSDYSFHKMAYLTFIPSNDDIYDCKVEHWSLDEPVLRHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFIIQGLRSVAPSRHPGPL
Protein: Tropomyosin 3 (J3KN67)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM
Protein: cathepsin X (EC 3.4.18.1) (Q5XJD4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MARVLFFYLFTLSGVFAGRYFNENEPCYKPQPRRNLQGVKTGPRPYESMNLKELPKEWDWRNIKGVNYVSTTRNQHIPQYCGSCWAHGSTSALADRINIKRKAAWPSAYLSVQNVIDCGDAGSCSGGDHSGVWEYAHNKGIPDETCNNYQAKDQDCKPFNQCGTCTTFGVCNIVKNFTLWKVGDYGSASGLDKMKAEIYSGGPISCGIMATDKLDAYTGGLYSEYVQEPYINHIVSVAGWGVDENGVEFWVVRNSWGEPWGEKGWLRIVTSAYKGGSGSQYNLAIEEDCMYGDPILPKNYL