wanglab/gogpt-training-data huggingface dataset:
Protein: Phototropin-1B (EC 2.7.11.1) (Q2RBR1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Protein kinase that acts as a blue light photoreceptor in a signal-transduction pathway for phototropic responses. Regulates a wide range of physiological activities in plants that maximize the efficiency of photosynthesis, such as chloroplast relocations, stomata opening, and leaf expansion (By similarity).
Interaction partners:
- Serine/threonine-protein phosphatase BSL1 homolog
Sequence:
MASKGTEGGHGGVERKEQQQQRGYQLPRDSRGSLEVFNPSSASSFRTAAAAPKSASPFLAIPDREEDNVVAQQRAAEWGLVLQTDHHTGLPQGVSARPSSGSARTSSEDNPQQQQSAAAIPRVSEELRAALSVFQQTFVVSDATHPNHPIMYASAGFFNMTGYTSKEVVGRNCRFLQGSGTDPHEIDKIRQSLANGSNYCGRILNYKKDGTPFWNLLTIAPIKDEDGRLLKFIGMQVEVSKYTEGKKDTVVRPNGLSESLIKYDARQKDHARSSVSELLLALKNPRSLSESSNNTLKRKSQESLSMSMSEVPSKRSSESGSRRNSRSGTRSSLQKINEVPDQVNRTRKSGLRAFMGFLGMGHGSVEKNMLKPRDEDPLIDSDDERPESFEDEFRRKEMRRGIDLATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYNREEILGRNCRFLQGPETDRATVRKIRDAIDNQAEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVQDDAAKEGVVLVKKTADNIDEAAKELPDANLRPKDLWANHSKVVLPNPHMKDTASWRAIQKVLESGESIGLKHFRPVKPLGSGDTGSVHLVELLNTGEYFAMKAMDKSIMLNRNKVHRATAERQILDLLDHPFLPTLYASFQTKTHICLITDYCPGGELFVLLDNQPLKVLHEDAVRFYAAEVVVALEYLHCQGIIYRDLKPENILLHRDGHISLTDFDLSCLTSCRPQVFLPEDADEKKGRKNGSYPIFFAEPMRASNSFVGTEEYIAPEIITGAGHTSAVDWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLAARQLMYRLLHRDPANRLGSYEGANEIKGHPFFRGINWPLIRATAPPKLEIPLFSKDDMEKKGLVTNNRTDMF
Protein: Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase) (Q4FZV0)
Organism: Rattus norvegicus (Rat)
Function: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
Subcellular location: Lysosome {ECO:0000250|UniProtKB:Q95327}.
Interaction partners:
- Glucosidase, alpha; neutral C
Sequence:
MHLHLLFLLALCGAGCMAAGPSYSLRGSWRVSNGNSSLELPATVPGYVHSALQQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNRSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTRYSFDVTNVVKDVNSLKLRFQSAVQYAECQSKAHTQYRVPPECPPVEQKGECHVNFIRKEQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDHLTFLPLYDNTSQAWTIEIEASFDVVSTKPVGGQVTIAIPELKTQQANHIELQHGQRIVKLLVKIRKDVTVETWWPHGHGNQTGYNTTILFALDGGLKIEKAAKVYFRTVQLIEEPITGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSELLQLLLQSAVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLESVRKEVTYQVRRLKSHPSVIIWSGNNENEVALRVNWFHVNPRDLGTYINDYVTLYVKTIREIVLSEDRSRPFIASSPTNGVKTMTEGWISKDPYSTQYGDMHFYDYFSDCWDWKVFPKARLVSEYGYQSWPSFSTLQKVSRQEDWSYSSRFSLHRQHHGNGNNEMLHQVQLHFQLPQRRDPVRAFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVNGEGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFAQRFFAPLLPVGFEDEGVFYVYGVSDLHKDYPTKLTVRLHRWSSQKPLCTFVSLSAVIKAGEAMVLFQMPVSKLLKRCKECTRDTCVVSFYLSTDNELFSPTNYHFLSSLKDAKGMVKANITVSISQKGDLFVFDLKSSTSAITPFVWLDVGSIPGRFSDNGFLMIKKELSVLFYPWKPTSKSELQQAFSVTSLTDLY
Protein: Spondin-2 (Mindin) (Q9WV75)
Organism: Rattus norvegicus (Rat)
Function: Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
Sequence:
MENVSFSLDRTLWVFLLAMLGSTAGQPLGGESVCTARPLARYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNEYVSNGLRDFAERGEAWALMKEIEAAGEKLQSVHAVFSAPAVPSGTGQTSAELEVHPRHSLVSFVVRIVPSPDWFVGIDSLDLCEGGRWKEQVVLDLYPHDAGTDSGFTFSSPNFATIPQDTVTEITASSPSHPANSFYYPRLKSLPPIAKVTFVRLRQSPRAFAPPSLDLASRGNEIVDSLSVPETPLDCEVSLWSSWGLCGGPCGKLGAKSRTRYVRVQPANNGTPCPELEEEAECAPDNCV
Protein: Ligand of numb-protein X 2a (F1R5N4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- NUMB endocytic adaptor protein.
- NUMB-like endocytic adaptor protein
- Kelch-like family member 11.
- PDZ domain containing 4
Sequence:
MGSLGEGVDPGMVSEALLEALCSECGQIHRTWENHLYNYRLEVDDDLVCHICLQPLVQPLDTPCGHTFCARCLRSFLQERDFCPLDRAHLQLQVCRRSSILVHKLLDKLSVTCPLTPSCSLSMPRCDLEAHLKHRCPGTQSQRTKLERTQMEGSEDRVTATNPPKSPQTEIKEDTPSPPAGSNACNNVPTWTEEPGIDNPAFEESTEEDSVHGLECALPRVKRPLSNPCIHLLRTGSSASSGWDFVETLPLSAEEGCVKLPSLPEGEITTIEVHRTNPYSEMGISIVGGNETPLINVVIQEVYRDGVIARDGRLLAGDQILQVNNVDISNVPHNFARSTLARPCATLQLTVLRERRCSARPPAATASPKGSPASIRITLHKRESSEQLGIKLVRRTDEAGVFILDLLEGGLAAKDGRLCSNDRVLAVNEHDLRHGTPELAAQIIQASGERVNLLISRSSKQTMAVHTGSTLTRDIWSHDHIPPLPSTATPSPVPSLHLARSSTQRDLSQCVNCKEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVQPHGCLSRDGRIKRGDVLLSINGQDLTYLSHSEAVGTLKSSATSCSVQLKALEVTMVEEPGLDEELLPPHENDYDASWSPSWVLWLGLPSYLHSSHEIVLRRSHPGSWGFSIVGGYEENHSNQAFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTAGMSHSALVPMLKEQRSRVALTVVSWPGSLI
Protein: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (O22854)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Accepts electrons from ETF and reduces ubiquinone. May act downstream of IVD and D2HGDH in the degradation of phytol or chlorophyll during dark-induced senescence and sugar starvation.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:16055629}.
Interaction partners:
- Electron transfer flavoprotein subunit beta, mitochondrial
- Electron transfer flavoprotein subunit alpha, mitochondrial
- Isovaleryl-CoA dehydrogenase, mitochondrial
- D-2-hydroxyglutarate dehydrogenase, mitochondrial
- L-2-hydroxyglutarate dehydrogenase, mitochondrial
- Geranylgeranyl diphosphate reductase, chloroplastic
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
Sequence:
MHRFLVKLSSSSSPFSNQLRSLKNQRLILPLLPSSKPFTSSSVSPPPSPLNASNRFGYPYSADLFRNLSPLNPNSRILGVNGITSSRCISSEAVRESIEYDVLIVGAGPAGLSAAIRLKQLSQEKNIDLSVCVVEKGAEVGGHIISGNVFEPLALDELLPHWRQEHAPIEIPASSDKFWFLTKDRAFSLPSPFDNKGNYVISLSQLVRWLGGKAEELGTEIYPGFSASEVLFDASDKVVGIATKDMGISKDGSKKENFQPGVDIKGRVTLFAEGCRGSLSERIIKKYKLREEVNAQHQTYALGIKEVWEIDESKHNPGEVIHTLGWPLDPKTYGGSFLYHMNDRQVALGLVVALNYHNPFLNPYEEFQKLKHHPAIKGILEGGTVLQYGARTLNEGGFQSIPYPVFPGGAIIGCSAGFLNVPKIKGTHTAMKSGMLAAEAAFGALHEGLNMNTYWDNLRDSWVWKELYAARNYRPAFEYGLLPGLAISAMEHYVLKGKVPFTLKHGKADHEATDLARKWTPIVYPKPDGVLSFDVPTSLYRSNTNHDHDQPSHLRLRDPKIPEKVNFPEYAAPESRYCPARVYEYIEDEEGKPKLQINAQNCLHCKACDIKDPKQNIEWTVPEGGGGPAYSLM
Protein: PCI domain-containing protein 2 homolog (CSN12-like protein) (Q9VTL1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for the export of nuclear mRNAs and involved in mRNA trafficking in the cytoplasm. Component of the nuclear pore complex (NPC)-associated TREX-2/AMEX complex (anchoring and mRNA export complex) which functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), thereby enabling the export of mRNAs to the cytoplasm through the nuclear pores. Within the complex, specifically promotes the association of factors involved in regulating nuclear mRNA export, such as Moe, sbr/NXF1 and the ORC complex, to the mRNPs particles. In the cytoplasm, functions independently of its role in the TREX-2/AMEX complex, to promote cytoplasmic mRNA trafficking together with nudC. Associates with translationally active polysomes.
Subcellular location: Nucleus {ECO:0000269|PubMed:18086857, ECO:0000269|PubMed:27016737}. Cytoplasm {ECO:0000269|PubMed:18086857, ECO:0000269|PubMed:33602059}. Nucleus membrane {ECO:0000269|PubMed:33602059}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:33602059}. Note=Shuttles in and out of the nucleus by a emb/Crm1-dependent mechanism (PubMed:18086857). The ubiquitinated forms are localized to the cytoplasm, the nonubiquitinated forms are localized to the nucleus, and both forms are associated with the nuclear membrane (PubMed:33602059). Associated with cytoplasmic microtubules (PubMed:33602059). Associates with mRNA in the nucleus and cytoplasm (PubMed:33602059). {ECO:0000269|PubMed:18086857, ECO:0000269|PubMed:33602059}.
Interaction partners:
- Protein xmas
- Enhancer of yellow 2 transcription factor
- Probable 26S proteasome complex subunit sem1
- Uncharacterized protein, isoform A
- SAC3/GANP/THP3 conserved domain-containing protein
- Uncharacterized protein, isoform B
- Nuclear RNA export factor 1
- Protein Rae1
- Dipeptidase
- Uncharacterized protein
Sequence:
MFGTVNNYLSGVLHAAQDLDGESLATYLSLRDVHVQNHNLYIAQPEKLVDRFLKPPLDEVVSAHLKVLYHLAQEPPGYMEAYTQQSAACGAVVRLLQQLKDENWCLPLMYRVCLDLRYLAQACEKHCQGFTPGHVLEKAADCIMACFRVCAADGRASEEDTKRLGMMNLVNQLFKIYFRINKLHLCKPLIRAIDNCIFKDSFPLPEQITYKYFVGRRAMFDSNYQAAVQYLSYAFSNCPDRFASNKRLILIYLVPVKMLLGYLPSKSLLQRYDLLLFLDLAMAMKAGNVNRFDEIVRDQELVLIRSGIYLLVEKLKFLVYRNLFKKVFVIRKSHQLDMGDFLSALHFVGLTDVSLDETHCIVANLIYDGKIKGYISHAHNKLVVSKQNPFPSVSL
Protein: RNA polymerase sigma factor sigF, chloroplastic (Sigma factor F) (Sigma-F) (Protein SINGLET OXYGEN-LINKED DEATH ACTIVATOR 8) (RNA polymerase sigma factor sig6) (Atsig6) (Sigma factor 6) (Q9LD95)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released. Regulates transcription in chloroplast in a DG1-dependent manner. Involved in light-dependent chloroplast development. Required during early plant development and primary leaf formation.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:10984613}.
Interaction partners:
- DNA-directed RNA polymerase subunit alpha
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Large ribosomal subunit protein bL28c
- Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain-containing protein
- Pentatricopeptide repeat-containing protein At5g67570, chloroplastic
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase 3, chloroplastic
- DNA-directed RNA polymerase subunit beta'
- 50S ribosomal protein L33
- Chloroplast sensor kinase, chloroplastic
Sequence:
MEATRNLVSSSPSFQTKTHLKSSYSSPSSVVMLHDQTTTPVVNSRHLNSLSRHFPASVLSQEPREESRPLSHALRDDRTSQLTLERRQFDELVSSREDEKFEQQLLHSTGLWNLLISPLTSETKLPAVVSPLADAELCDVVALAQKALSASKQAALLVDDTEANPSDNIKDSLSTSSSMSLPEKGNIVRSKRQLERRAKNRRAPKSNDVDDEGYVPQKTSAKKKYKQGADNDDALQLFLWGPETKQLLTAKEEAELISHIQHLLKLEKVKTKLESQNGCEPTIGEWAEAMGISSPVLKSDIHRGRSSREKLITANLRLVVHIAKQYQNRGLNFQDLLQEGSMGLMKSVEKFKPQSGCRFATYAYWWIRQSIRKSIFQNSRTIRLPENVYMLLGKVSEARKTCVQEGNYRPSKEELAGHVGVSTEKLDKLLYNTRTPLSMQQPIWSDQDTTFQEITPDSGIETPTMSVGKQLMRNHVRNLLNVLSPKERRIIKLRFGIDGGKQRSLSEIGEIYGLSKERVRQLESRALYRLKQNMNSHGLHAYADLLV
Protein: Replication factor A protein 1 (Q9GYL9)
Organism: Caenorhabditis elegans
Interaction partners:
- BTB domain-containing protein
- DUF38 domain-containing protein
- non-specific serine/threonine protein kinase
- DNA repair protein RAD51 homolog
- Endoplasmic reticulum junction formation protein lunapark-1
- Nematode Specific Peptide family, group D
- Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
- DNA replication complex GINS protein SLD5
- F-box domain-containing protein
- Protein TIPIN homolog
Sequence:
MDRELTPISSLSPEISNFAICERVTFMKEITNGVSFDLTDTYGESIRCVAFGAAGEYCKRELKLNELCYVMDGKIQLKSDDYPSYTTHACEIIIFNEHNVKIRQEDPATDQNVDAPPAAVTPIANLNDSVDNFKIHGRVTLMDDKRRPEKVFSFEITDVNGYTIRCVAFGELGVRLYGSIAKDQSYYLTGGKVKNGHTLYNQTGHAFEIILDEFPTIEPAPAVLTVPKLNLNRVMLCNVQNEQYYRKPIDVIVAVEEINDFLDDYHPIENKPPVLRNMVVIDDSNFRIRLTLWGYRAMDSGVEEFQNKIVAFKGIVPTQFEGEL
Protein: Flagellin (Phase 1-I flagellin) (P06179)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Subcellular location: Secreted. Bacterial flagellum.
Interaction partners:
- Flagellar secretion chaperone FliS
- Flagellar hook-associated protein 2
- Flagellar hook-associated protein 1
- Flagellar hook protein FlgE
- RNA polymerase sigma factor FliA
- Flagellar hook-associated protein 3
- Flagellar basal body rod protein FlgB
- Flagellar basal-body rod protein FlgG
- Flagellar motor switch protein FliM
- Phase 2 flagellin
Sequence:
MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Protein: Tubby-like F-box protein 10 (AtTLP10) (SKP1-interacting partner 26) (Q9FRH7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q86PC9}.
Interaction partners:
- Protein TWIN LOV 1
- Phospholipid scramblase
- SKP1-like protein 1A
Sequence:
MSFRGIVQDLRDGFGSLSRRSFDFRLSSLHKGKAQGSSFREYSSSRDLLSPVIVQTSRWANLPPELLFDVIKRLEESESNWPARKHVVACASVCRSWRAMCQEIVLGPEICGKLTFPVSLKQPGPRDAMIQCFIKRDKSKLTFHLFLCLSPALLVENGKFLLSAKRTRRTTRTEYIISMDADNISRSSNSYLGKLRSNFLGTKFLVYDTQPPPNTSSSALITDRTSRSRFHSRRVSPKVPSGSYNIAQITYELNVLGTRGPRRMHCIMNSIPISSLEPGGSVPNQPEKLVPAPYSLDDSFRSNISFSKSSFDHRSLDFSSSRFSEMGISCDDNEEEASFRPLILKNKQPRWHEQLQCWCLNFRGRVTVASVKNFQLVAARQPQPQGTGAAAAPTSAPAHPEQDKVILQFGKVGKDMFTMDYRYPLSAFQAFAICLSSFDTKLACE
Protein: Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4) (Q9WTY9)
Organism: Rattus norvegicus (Rat)
Function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K. Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. Mediates UV irradiation induced up-regulation of the gene expression of CXCL14. Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development. Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway. MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells.
Interaction partners:
- non-specific serine/threonine protein kinase
- MAP kinase-activated protein kinase 3
- Cyclic AMP-dependent transcription factor ATF-2
- mitogen-activated protein kinase kinase
- mitogen-activated protein kinase kinase
- Transcription factor Jun
- Dual specificity mitogen-activated protein kinase kinase 1
- Dual specificity mitogen-activated protein kinase kinase 2
- Protein c-Fos
- Cellular tumor antigen p53
Sequence:
MSLIRKRGFYKQDINKTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVYTPATSVRNFQDFYLVMPFMQTDLQKIMGMEFSEEKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDKAAKSYIQSLPQSPKKDFTQLFPRASPQAVDLLDKMLELDVDKRLTAAQALAHPLFEPLRDPEEETEAQQPFDDALERENLSVDEWKQHIYKEIANFSPIARKDSRRRSGMKLQ
Protein: Tropomyosin 2 (beta) (Tropomyosin beta chain) (Zgc:86810) (Q6IQD7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Slow troponin T
- Troponin T type 1
- Fast muscle troponin I, tandem duplicate 4)
- Novel slow skeletal troponin T family protein
- Troponin T2d, cardiac.
- Troponin T type 2a
- Tnnt3b protein)
- Troponin I, fast skeletal muscle
- Troponin C, slow skeletal and cardiac muscles
- Tropomodulin 2.
Sequence:
MEAIKKKMQMLKLDKENAIDRAEQAEIDKKGAEDKCKQLEEELLALQKKLKGVEDELDKYSESLKDAQEKLEQAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRATKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERSEERAEVAEAKSGDLEEELKNVTNNLKSLEAQAEKYSTKEDKYEEEIRVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKLKGKALSEELDLALNDMTTL
Protein: Immunoglobulin lambda-like polypeptide 1 (CD179 antigen-like family member B) (Ig lambda-5) (Immunoglobulin omega polypeptide) (Immunoglobulin-related protein 14.1) (CD antigen CD179b) (P15814)
Organism: Homo sapiens (Human)
Function: Critical for B-cell development.
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:P20764}. Secreted {ECO:0000269|PubMed:9419212}. Note=In pre-B cells, localizes predominantly to the endoplasmic reticulum. {ECO:0000250|UniProtKB:P20764}.
Interaction partners:
- Immunoglobulin iota chain
- B-cell antigen receptor complex-associated protein alpha chain
- B-cell antigen receptor complex-associated protein beta chain
- Immunoglobulin heavy variable 4-38-2
- Pre-B lymphocyte protein 3
- Immunoglobulin J chain
- Phosphoacetylglucosamine mutase
- B-cell linker protein
- Immunoglobulin lambda-like polypeptide 5
- V
Sequence:
MRPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSRSSLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTHVFGSGTQLTVLSQPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGSTVEKTVAPAECS
Protein: dynamin GTPase (EC 3.6.5.5) (A0A0R4IIR1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Caveolin
- Myotubularin 1.
- Dynamin 2b
- SH3 domain-containing GRB2-like 2a, endophilin A1
- Clathrin heavy chain
- WASP-like actin nucleation-promoting factor a.
- Clathrin heavy chain
- Nitric oxide synthase-trafficking.
- Ryanodine receptor 1a
- Cyclin G-associated kinase.
Sequence:
MGNRGMEELIPLINKLQDAFSSIGQSCNLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLVNNKAEYAEFLHCKGRKFVDFDEVRQEIEAETDRITGSNKGISPIPINLRVYSPNVLNLTLIDLPGMTKVAVGDQPPDIEHQIRDMIMQFITRESCLILAVTPANMDLANSDALKVAKEVDPQGLRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIDGRKDIRAALAAERKFFLSHPSYRHMAERMGTPHLQKALNQQLTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKCIEGSGDQVDTAELSGGARINRIFHERFPFELVKIVFDEKELRREISHAIKNVHGVRTGLFTPDLAFEAIVKKQIIKLKEPCLKCIDLVIQELINTFRQCTNKLSSYPRLREETERIVTTYVREREGKTKDQVLLLIDTELSYINTNHEDFIGFANAQQRNIVNKKRAIPNQGEILVIRKGWLTLNISIMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKLRDVEKGFMSTKHIFAIFNTEQRNVYKDLRQIELACDSQEDMDSWKASFLRAGVYPEKDQVESEEAAPADSFSMDPQLERQVETIRNLVDSYIGIVNKTIRDLMPKTIMHLMINSAKDFIHSELLAYLYSSGDQNSLMEESADQAQRRDEMLRMYHAIKEALSIIGDISTSTISTPVPPPVNDSWIPETSPTPQRRPPTSAPPPNRPPAVRGPTPGPPPLNPTPSFAAPPIPSRPGQPMNAFGNSSQDPFSAPPQIPSRPARIPPGVPSRRPPGAPNRPTIIRPAEPSLLD
Protein: Uncharacterized protein T21J18_100 (Q9M300)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAVLSVGFFACRSHFPVLPLFYCFSKVQLNTVAAAMETVDDKDSDHHHDKGSNKTSKAPEWKKLNSKDLGITTSMISKPTRIVLNGLKSKGYDVYLVGGCVRDLILKRTPKDFDILTSAELREVVRSFSRCEIIGKKFPICHVHIGNDMIEVSSFSTSAQNSLRNTRTGSGKSNGSYDEDSIRFNNCLQRDFTINGLMFDPYAKVIYDYLGGIEDIKKAKVRTVFHAGTSFQEDSARILRGTRIAARLGFTISKETAHFLKNLSFLVQRLHRGRILLEMNYMLAYGSAEASLRLLWKFGILEILLPIQAAYLVRTGFKRRDKRSNLLLSLFGNLDKLLAPDKPCHSSLWLTILALHKALADQPRYPSVVAAFSLAVHNGGDVLEAVKNTRKVTKPHNRSFFELLEPEEMDSQTLLDEVMDFDSSIKEALGQMTDGRFISKAMAAYPQAPYSDMVFIPLQLYLDARRIFECVKENGQKGFVPKQDSKREPEDDLETKPILKKHKENSEEENKEQIKGTVELLETKSDQAPVKETVEGLDETPDSVEVPKKYMSGLLIRCFPSRKKTLYVCCLPRDTKMPDIIDFFKDVGQVVSVQLTTKRNGLRLSTGFVEFASANEAKKALDMKNGEYLCGNKLILGMASCENIAQPKYEDYIQQESLPIEEEETPPKIVQSGANTLGCSIQAAAFSMTDILSFHFYRLDFFNDVGEVVSVRLIVSPESKHVGYGFVEFASPCLANMALEKKNGEYLHDHKIFLGVAKTAPYPPRIKYNLAEKLWYEDYLLRDSLLIEEDETVEGLDETPSCVEAVALREKVLIIAHVPRRTKISHIIDFFKDAGQVVNVRLIVDQKGKPFGRGFVEFTSADEAKKVRLVYSNDEKYFTSH
Protein: Serine/threonine-protein kinase ZRK1 (EC 2.7.11.1) (Protein RESISTANCE RELATED KINASE 1) (Quantitative resistance to Xanthomonas campestris pv. campestris 568) (Quantitative resistance to Xcc568) (Q9SVY5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine/threonine-protein kinase that confers a broad-spectrum quantitative disease resistance (QDR) to the pathogenic biotrophic bacteria Xanthomonas campestris (e.g. pv. campestris (Xcc), pv. raphani, pv. armoriaceae and pv. incanae) by restricting bacterial spread to the vascular system from the infection site; X.campestris causes black rot disease in crops. Seems to not have any kinase activity.
Interaction partners:
- Disease resistance RPP13-like protein 4
- Probable serine/threonine-protein kinase PBL2
- At5g22540
- Disease resistance protein RRS1
- Apoptosis inhibitory protein
- Prolamin-like protein
- Large ribosomal subunit protein P1y
Sequence:
MKKQYLKSGSGTRKEKDKAKRWFLDNGSIFLRELVADCNGKSIPIRSFSPEQILKATNNFDSSCFVSQDVYYKWYRGEIEDRSYMIKRFSEDEITGKRHRVKEVYNDIVLSARMSNHSNFLQLLGCCLEFPFPVLVFEFAEHGAMNQRGGVIVNGEESLLPWSVRLKIGKEIANAVTYLHTAFPKIIIHRDVKPMHVFLDKNWTAKLSDLSFSISLPEGKSRIEAEWVLGTFGYIDPLYHKTCFVTEYTDVYSFGICLLVIITGKPAIMTISDGDLQGILSLVRELCENGKLDEVIDPRLMKDITSGQRLQVEACVVLALRCCKERDEDRPKMIQVAKELKQIEASLKNSS
Protein: Envelope glycoprotein M (gM) (Q6SW43)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Envelope glycoprotein important for virion assembly and egress. Plays a role in the correct incorporation of gH-gL into virion membrane. Directs the glycoprotein N (gN) to the host trans-Golgi network.
Subcellular location: Virion membrane {ECO:0000255|HAMAP-Rule:MF_04035}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_04035}. Host Golgi apparatus, host trans-Golgi network {ECO:0000255|HAMAP-Rule:MF_04035}. Host endosome membrane {ECO:0000255|HAMAP-Rule:MF_04035}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_04035}. Host nucleus inner membrane {ECO:0000255|HAMAP-Rule:MF_04035}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_04035}. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs. {ECO:0000255|HAMAP-Rule:MF_04035}.
Interaction partners:
Sequence:
MAPSHVDKVNTRTWSASIVFMVLTFVNVSVHLVLSNFPHLGYPCVYYHVVDFERLNMSAYNVMHLHTPMLFLDSVQLVCYAVFMQLVFLAVTIYYLVCWIKISMRKDKGMSLNQSTRDISYMGDSLTAFLFILSMDTFQLFTLTMSFRLPSMIAFMAAVHFFCLTIFNVSMVTQYRSYKRSLFFFSRLHPKLKGTVQFRTLIVNLVEVALGFNTTVVAMALCYGFGNNFFVRTGHMVLAVFVVYAIISIIYFLLIEAVFFQYVKVQFGYHLGAFFGLCGLIYPIVQYDTFLSNEYRTGISWSFGMLFFIWAMFTTCRAVRYFRGRGSGSVKYQALATASGEEVAALSHHDSLESRRLREEEDDDDEDFEDA
Protein: Mitochondrial translocase subunit (Q385M9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Tim10-like domain-containing protein
- Mitochondrial import inner membrane translocase subunit
Sequence:
MNQSSSLWGEEFEVLKQMQEDRMNFANNMTCHERCVSQYWFNNFYGPEHRCMRNCLEKLNQVGVITNIVFTKHEQGKTGSKGK
Protein: Metallothionein (MT) (Copper-binding metallothionein) (Cu(I)-binding metallothionein) (Mycobacterial metallothionein) (P9WK09)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Metallothioneins are small proteins that have a high content of cysteine residues wich allow them to bind heavy metal ions through clusters of thiolate bonds. MymT binds up to seven ions of Cu(+), with a preference for four to six Cu(+) ions, in a solvent-shielded core. MymT protects M.tuberculosis from copper toxicity.
Interaction partners:
- Copper-sensing transcriptional repressor RicR
- Lipoprotein LpqS
- Putative permease Rv2963
- Multicopper oxidase MmcO
- Copper-sensing transcriptional repressor CsoR
Sequence:
MRVIRMTNYEAGTLLTCSHEGCGCRVRIEVPCHCAGAGDAYRCTCGDELAPVK