wanglab/gogpt-training-data huggingface dataset:
Protein: F-box protein At1g67340 (Q9FYF9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Probable transcription factor PosF21
- Elongin-C
- At5g57860
Sequence:
MLPSRKTKRVFSCDFTPGRKRRRCVVVPSSVSPVPENTTGADLLDSIPDDLVISILCKLGSTSRCPADFINVLLTCKRLKGLAMNPIVLSRLSPKAIAVKAHNWSEYSHRFLKRCVDAGSLEACYTLGMIRFYCLQNRGNGASLMAKAAISSHAPALYSLAVIQFNGSGGSKNDKDLRAGVALCARAAFLGHVDALRELGHCLQDGYGVPQNVSEGRRFLVQANARELAAVLSSGIQARSTWLSLSQPPPPVVPNHGQQTCPLLSDFGCNVPAPETHPANRFLADWFAVRGGDCPGDGLRLCSHAGCGRPETRKHEFRRCSVCGVVNYCSRACQALDWKLRHKMDCAPVQRWLEEGDGGEGNVQIDGNGNGDNVLLPMS
Protein: Sll1507 protein (P72989)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- Slr1579 protein
Sequence:
MDLVVMNVRFPHFCLSLMFASLLAGAGTLPLAAAERVVLTYSVLRESISIEELGELSRTGKVSPSLKAYLKMANKNPEELRGWLNRPFQADPVTLSRVLNSFAGEYVLNQVGQVIHTPSKRDNKEALRGAIISSAEKDNQVRLIEVLENYPTPELHVNGDRLMELYQQVEGLTAMLGRLPF
Protein: Epididymis secretory protein Li 114 (Thioredoxin-like 1, isoform CRA_c) (V9HW51)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH
Protein: Zinc finger protein 658 (Q5TYW1)
Organism: Homo sapiens (Human)
Function: Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription intermediary factor 1-beta
Sequence:
MNMSQASVSFQDVTVEFTREEWQHLGPVERTLYRDVMLENYSHLISVGYCITKPKVISKLEKGEEPWSLEDEFLNQRYPGYFKVDHIKGIREKQEKPLWQEIFISDADKTLSKEGQKVLEKPFNLEIAPELSEKISCKCDSHRMNLPVASQLIISERKYSRKKTEYMNVCEKLQLDIKHEKAHAEEKSYEHGENAKAFSYKKDQHWKFQTLEESFECDGSGQGLYDKTICITPQSFLTGEKSCKDDEFRKNFDKITLFNHMRTDTRGKCSDLNEYGTSCDKTTAVEYNKVHMAMTHYECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEHNECTDALYQKLDFTAHQRIHTEDKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRIHTGEKPYECDECGKTFVRKAALRVHHTRMHTREKTLACNGFGKS
Protein: Chromosome 12 open reading frame 5, isoform CRA_b (TP53 induced glycolysis regulatory phosphatase) (A0A0U1RQD1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
Protein: Uncharacterized protein (Q38AZ3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNNGGPYNGYPLMRSGCGTSKQRKNGPPERAATGGVEIAGGGDWLNIVSQTSYQRAILSRSSAQSNDVGGSTPQQGTSTCERSHKDAVSGSNSTFTLADPAAVAFPPLAVGSTSKSSFQSTERCAAVPVDISCPLPIDFLWPRAFFGRMHVATGGAAASRRDTHGMGPPAVGMEDMSSGCSLKENATKGGSVAVRETQLSSPSIDDSSTMNSLQAPYPVDWTPTLGDDLAAPGERGFRELRGLLGAVFRECCPKLFSALRVPHYFMEKGVLDDAKLRQHRGGRRQEAELSERDMIPLPLLNEINNVVDERDRSPKYTMTSQSDSSDLLDHKTAVFRDPSSLQNAPQEGQNEEDPAQIFAGLLHQLAVAGNDSSATDGVSVSFTLGNNGDSVQDSATGGEGTFSPQWLRSYSYR
Protein: protein-tyrosine-phosphatase (EC 3.1.3.48) (A0A8I6A706)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MDQREILQQLLKEAQKKKINREEFANEFLKLKRQSTKYKADKIYPTTVAQRPKNIKKNRYKDILPYDHSLVELSLLTSDEDSSYINASFIKGVYGPRAYIATQGPLSTTLLDFWRMIWEYRVLVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFSISCETEKKKSDYKIRTLKAKFNSETRIVYQFHYKNWPDHDVPSSIDPILQLIWDMRCYQEDDCVPLCIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLELFKRHVDIISDNHREREIQAECSIPEQKLTIEADSYPLDFPKNAVRDAKMTNQQSKQGAEAESTEVSSFGLRTSKISAKEELVLHSKSSPSFDCLELNCECNKAVITRNGQARASLVVGEPLQKYQSLDFGSILFGSCPSALPINTASRCHNSKGPVKRTKSTPFELIQQRKTNELAVEDGSSCLESQLLEHGLMELQAQKVAHASSEELNYSLPRACERPACDASCVPQDGPGALREHLCMSLAEDPYFSSSPPNSAGSKMSFDLPEKQDGATSPGAQLPASSAASSSYSNPRDSLMESTLTSFPPPINQETAIEATSARTDDEIPPPLPERTPESFIVAEAAGEPSPSITESLPLAGKSGVTLECGGTSESQSHDLVAFTSSKNVELGSPKSDQHQDGSPPPPLPERTLESFFLADEDCIQAQPMKPSSISYPETTEISTSSKQTLKTPGKSFTRIFTLHIFPLVTGVCNSPSPSKPTECVQPKNSSSFLNFGFGTRFSKPKGPRNPPSTWNI
Protein: 18.6 kDa class III heat shock protein (18.6 kDa heat shock protein) (OsHsp18.6) (Q6K7E9)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MTELFDTAVTSLLHLPEVLDRLGAAAGDRRSAGDHAHHAAHGHGQHRISGIGGGAPVDIMETPGEYAFVLDVPGLSKSDIQVTLEEDRVLVMKSSNGAGNGKRKREEEEGECKYIRLERRASPRAFARKFRLPEDADTGGISARCENGVLTVTVKKRPPPEKKTKSVQVTIA
Protein: Ras-associated protein 2-like, isoform C (Ras-associated protein 2-like, isoform D) (A0A0B4LGJ4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00046278}; Lipid-anchor {ECO:0000256|ARBA:ARBA00046278}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00046278}.
Interaction partners:
Sequence:
MRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAEGNALAQLWDCPFIEASAKDRINVNEVFATIVREMNLTQENRQKKNYCCCTLL
Protein: Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-) (Q5VVL7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}.
Interaction partners:
Sequence:
MAAVRMLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPSFKYSHPHHFLKTTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLSFMPFFLKYYFSWKS
Protein: Catalase (EC 1.11.1.6) (P04762)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Subcellular location: Peroxisome matrix {ECO:0000269|PubMed:26961980}.
Interaction partners:
- 2-Hydroxyacid oxidase 2
- 2-Hydroxyacid oxidase 1
- Kynureninase
- 3-hydroxyanthranilate 3,4-dioxygenase
- Superoxide dismutase, mitochondrial
- Superoxide dismutase
- Regucalcin
- Trehalase
- Extracellular superoxide dismutase
- Protein YIPF6
Sequence:
MADSRDPASDQMKQWKEQRAPQKPDVLTTGGGNPIGDKLNIMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAMLFPSFIHSQKRNPQTHLKDPDMVWDFWSLCPESLHQVTFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLPVEEAGRLAQEDPDYGLRDLFNAIASGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPANYFAEVEQMAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMHDNQGGAPNYYPNSFSAPEQQGSALEHHSQCSADVKRFNSANEDNVTQVRTFYTKVLNEEERKRLCENIANHLKDAQLFIQRKAVKNFTDVHPDYGARVQALLDQYNSQKPKNAIHTYVQAGSHIAAKGKANL
Protein: Pentatricopeptide repeat-containing protein At5g61370, mitochondrial (Q9FLJ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- non-specific serine/threonine protein kinase
Sequence:
MMSTTVRLNRFTYLTSTAKLTRYFCSHHLVDRSETALHEVIRIVSSPVGGLDDLEENLNQVSVSPSSNLVTQVIESCKNETSPRRLLRFFSWSCKSLGSSLHDKEFNYVLRVLAEKKDHTAMQILLSDLRKENRAMDKQTFSIVAETLVKVGKEEDAIGIFKILDKFSCPQDGFTVTAIISALCSRGHVKRALGVMHHHKDVISGNELSVYRSLLFGWSVQRNVKEARRVIQDMKSAGITPDLFCFNSLLTCLCERNVNRNPSGLVPEALNIMLEMRSYKIQPTSMSYNILLSCLGRTRRVRESCQILEQMKRSGCDPDTGSYYFVVRVLYLTGRFGKGNQIVDEMIERGFRPERKFYYDLIGVLCGVERVNFALQLFEKMKRSSVGGYGQVYDLLIPKLCKGGNFEKGRELWEEALSIDVTLSCSISLLDPSVTEVFKPMKMKEEAAMVDRRALNLKIHARMNKTKPKLKLKPKRRSKTKKKNLQH
Protein: Collagen alpha-2(I) chain isoform X1 (Collagen alpha-2(I) chain precursor) (Collagen, type I, alpha 2) (Q6IQX2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Collagen, type I, alpha 1a.
- procollagen-lysine 5-dioxygenase
- Cartilage-associated protein.
- procollagen-proline 3-dioxygenase
- Collagen, type VI, alpha 3.
- Collagen alpha-2
- Peptidyl-prolyl cis-trans isomerase
- Integrin beta
- Sp7 transcription factor.
- Periostin
Sequence:
MLSFVDTRILLLLAVTSYLASCQSGLKGPKGPRGERGPKGPDGKPGRPGLPGPAGPPGPPGLGGNFAAQYDGAKGPDPGPGPMGLMGPRGPSGSPGAPGAQGLQGHAGEPGEPGQAGAIGARGPPGPPGKNGEDGNNGRPGKPGDRGVLGAQGARGFPGTPGLPGMKGHRGYNGIDGRKGEPGAAGAKGENGAAGSNGTPGQRGGRGLPGERGRVGPAGPAGARGADGNTGPAGPAGPLGSAGPPGFPGAPGPKGELGPAGPTGPSGAQGQRGEPGPNGAVGPVGPPGNPGANGINGAKGAAGLPGIAGAPGFPGPRGGPGPQGPSGASGPRGLGGDPGPVGVKGDSGVKGEPGSAGPQGPPGPSGEEGKRGSTGEQGPTGPLGLRGPRGAAGTRGLPGLAGRSGPMGMPGPRGGVGAPGARGPPGDAGRAGEAGLVGARGLPGSPGSSGPPGKEGPSGAAGQDGRTGPPGPTGPRGQPGNIGFPGPKGPSGEAGKPGEKGPVGPTGLRGSPGPDGNNGPAGPVGLAGAPGEKGEQGPSGAPGFQGLPGPAGPVGEAGKPGDRGIPGDQGVSGPAGVKGERGNPGPAGAAGAQGPIGARGPSGTPGPDGNKGEPGAVGPAGAPGPQGAAGMPGERGAAGTPGAKGEKGEAGYRGLEGNAGKDGARGAPGPSGPPGPAGANGDKGETGSFGPPGPAGPRGAPGERGESGPAGPSGFAGPPGADGQTGPRGEKGPAGGKGDAGPAGPAGPAGNTGPLGPSGPVGPPGARGDSGPTGLTGFPGAPGRVGPPGPAGIVGPAGLTGPAGKDGPRGPRGDVGPAGPPGENGMIGPLGLAGEKGPPGEAGAPGAPGPAGPQGQLGSQGFNGLPGSRGDRGLPGIPGSVGEPGRVGPAGAPGARGPGGNIGMPGMTGPQGEAGREGSPGNDGPPGRPGAAGIKGDRGEPGSPGTAGPVGAPGPNGPSGAVGRPGNRGESGPSGPTGAVGPAGARGAPGPAGPRGEKGVAGEKGDRGMKGLRGHPGLQGMPGPNGPSGDSGPAGIAGPSGPRGPAGPNGPAGKDGSNGMPGAIGPPGHRGPAGHVGPAGPPGSPGLPGPPGPSGGGYDTSGGYDEYRADQASLRAKDYEVDATIKSLNTQIENLLSPEGSKKNPARTCRDIRLSHPEWSSGFYWIDPNQGCTMDAIKAFCDFSTGQTCIHPHPESIPRKNWYRSSQEKKHTWFGETINSGTEFAYNDETLSPQSMATQLAFMRLLANQAVQNITYHCKNSIAYMDAENGNLKKAVLLQGSNDVELRAEGNSRFTFSVLEDGCSRHTGQWSKTVIEYRTNKPSRLPILDIAPLDIGGADQEFGLDIGPVCFK
Protein: Large ribosomal subunit protein uL15m (39S ribosomal protein L15, mitochondrial) (Q8T9L3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAHLRETSDKALKLLRTLPRVQIGNLRPNPNSKQNDKRGRAQHGGDKHGAGNKGSGQRQNFMRLGYETGNQPFYLRFPYEPYYKGHHLKRQYPPISLLQLQVLIDTNRIDISQPIDISTLCNSGLLKLKPAEMEYGFQLTDDGLDNFQAKINIEVQHASEAVIAAIEKNGGVIRTAYYDPRSLHMLANPKKWFEKGVPIPRRMLPPQDAVDYYTDPKNRGYLANPEAISQDRLVLAQKYGYQLPKIEEDSAYEMLTTAKDPRQVFYGLEPGWLINIVDKTIIKRKQ
Protein: Serine/threonine-protein kinase OXI1 (EC 2.7.11.1) (AGC serine/threonine-protein kinase subfamily 2 member 1) (Protein OXIDATIVE SIGNAL-INDUCIBLE 1) (Q9LSF1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in oxidative burst-mediated signaling. Required for basal resistance to P.parasitica infection and root hair growth. Partly required for the activation of MPK3 and MPK6 by hydrogen peroxide and cellulase elicitor.
Interaction partners:
- non-specific serine/threonine protein kinase
- Mitogen-activated protein kinase 6
- PTI1-like tyrosine-protein kinase 2
- Probable receptor-like protein kinase At2g47060
- Mitogen-activated protein kinase 8
- Respiratory burst oxidase homolog protein D
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit P
- G-type lectin S-receptor-like serine/threonine-protein kinase At1g61370
- Respiratory burst oxidase homolog protein C
Sequence:
MLEGDEKQSRALDFNRLEVLSLLGRGAKGVVFLVRDDDAKLLALKVILKEAIEKKKKGRESEDDEYKRVSFEQGVLSRFDHPLFPSLHGVLATDKVIGYAIDYCPGQNLNSLRKMQSESMFSDEIIRFYAAELVLALDYLHNQGIVYRDLKPDNVMIQENGHLMLIDFDLSTNLAPRTPQPSPSLSKPSPTMKRKKRLFRFTSFCNSGISPQESISVHSSSTLAVSDSSGEKSNSFVGTEEYVAPEVISGDGHDFAVDWWSLGVVLYEMLYGATPFRGSNRKETFYRILSKPPNLTGETTSLRDLIRRLLEKDPSRRINVEEIKGHDFFRGVDWEKVILVSRPPYIPAPDDGGDKGTDVNTKMDVENIVQEIFAARQEREKQSGDNNKNANMKIKDNTSGEWVKGLNNNHDLESDNNFLVF
Protein: Transmembrane 4 L6 family member 1 (Membrane component chromosome 3 surface marker 1 homolog) (Tumor-associated antigen L6) (Q64302)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane; Multi-pass membrane protein. Note=Colocalizes with SDCBP2 in the apical region of the cell. {ECO:0000250|UniProtKB:P30408}.
Interaction partners:
- Epithelial discoidin domain-containing receptor 1
Sequence:
MCYVKCARYIGYSLVWAAVFCIVANALLYFPNGETKYATEDHLSRFVWYFAGIVGGGLLMLLPAFVFIGMDEEDCCGCCGYENYGKRCSMLSSVLAALIGIVGSAYCVIVASLGLAEGPKCSDAHGVWNYTFASTEGQYLLNSSMWSKCYEPKHIVEWHVTLFSILLAFAAVEFILCLIQVINGMLGGLCGYCCSRQQQYNC
Protein: Mucin 21 (A8QW50)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
STTTASSTVSDSTPTPSTNASSSASGSTPTQTTTASRSASGSVPTLTTIAFSTASGSTPTLTTTASNSASSSSPTPTTTGLSKTSASSLSLTSTMTSITSASTFTPASIRTSKASASTSTSASIRTSIAFASTSTPTTSGPSTASVSTLNSTSIRTSTGSSSSLSATHTSSSLTVSTGTHTTSNHTGTPVMEVKPSGSLKPWEIFLITLASVIVVMGLSAGLFIYVRRYLSLRNAADGIFYNSHPDPGGSAMTPGSLTCSWRRPRTFNVVEMTRI
Protein: Sulfotransferase 6B1 (EC 2.8.2.-) (Thyroxine sulfotransferase) (EC 2.8.2.n2) (F1QYJ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including dopamine, T3 (triiodo-L-thyronine), T4 (thyroxine), flavonoids, isoflavonoids, and other phenolic compounds.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P0CC03}.
Interaction partners:
- Cytochrome P450, family 2, subfamily AA, polypeptide 11
- Si:dkey-65b12.6.
- Palmitoyltransferase ZDHHC23-B
- WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein
- MAM domain-containing 2b
- Galactose-3-O-sulfotransferase 1a
- Chemerin-like receptor 2
- Splicing factor YJU2
- Deoxyribonuclease
Sequence:
MSQMKSRMETAAKMKDEDKLYRRDGILYSTVLSPPETLDKLKDLQAREDDLILVAYPKCGFNWMVAVLRKIINASTGKDEKPPERPPLVEFLPPTVQEEMAQMPPPRLLGTHLHPDNMPATFFTKKPKILVVFRNPKDTVVSYYHFMNKNPVLPNAESWDKFFSDFMTGDVSWGSYFDHALAWEKRIDDPNVMIVMYEDLKQNLPEGVKKISEFFSLPLTDEQVSSIAGQSTFSAMVENSQKSHGNFGSIFFRKGEVGDWKNHFSEAQSKQMDELYHSKLAGTKLAARMNYDLYCQ
Protein: Heat shock transcription factor 1 (A0A8I6AMW4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSSSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKEEPPSPPHSPRVLEASPGRPASMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAPPAPSTPEKCLSVACLDNLARAPQMSGVARLFPCPSSFLHGRVQPGNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDIQELLSPQEPPRPIEAENSNADSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
Protein: C2 domain-containing protein (Q95QH7)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MVKLDFSSQDEENDEDLTKEFVRDEAPMEETTSEAVKQIATTTKETLKDVVVNKVIDVKDVVKEKVMQQTGMPEWAFVFLGFVFILLVLACAFCLIRKLFGKKRHGEKNKKGGLKGFFGKGQDVVDGKNIQGMAQDLEELGDAMEQNEKEQAEEKEEVKLGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKLEMFGEDRKRLKKKKTNIKRKTLNPYFNESFVFDKLPLHKMKKVSLMITVMDYDKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTLGPVEEEGDKKDDKK
Protein: HMG box domain-containing protein (Q3US89)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MKQLPAATVRLLSSSQTITSVVSVVKELIENSLDAGATSIEVKLENYGFDKIEIRDNGEGIKAVDVPVMAVKYYTSKISSHEDLGNLTTYGFRGEALGSICNVAEVVVTTRTSADDFSTQYVLDGSGHILSQKPSHLGQGTTVTALKLFKNLPVRKQFYSTAKKCKDELKNVQDLLISYGVLKPDVRITFVHNKAVIWQKSRVPDHRMALMSVLGTAVMGNMESVEQHCEQSQIYLSGFFPKHDADHNSTSLSTPERSFIFINSRPVHQKDILKLIRRYYNLKCLKESTRLYPIFFLKIDVPSAEVDINLTPDKSQVLLQNKESVLIALENLMMTCYGPLPTTESSENNRVDISSANMVVSQTTETDVLFNKMESFGNNYPNADTSAIHFQKDESRKNIDHHLNEQINIGNYFDGHFSGDINKDTFQNIPMNNLSSETNQSNHSETHSVGSMEHIQGENGRNGTGGSGGDGRETLPEKALEICADDWSKGNLCNSMGENIEPVKILVPQKSLSCKVTSSHPRLEPETLSDGPCSRTSDVIHNRSGRLTAYDLISSRAVKKPMSASALFIQDHRTQFLTENPKTGLEDATEQIKARWETLSEEEKHKYEEKAKKDLERYNNQMKKAIEQETQVSLKDGRKKRATSSWGWTQKHKVKDSSNQPKLDELFQS
Protein: Porphobilinogen deaminase (PBG) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (Q09899)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Interaction partners:
- Uroporphyrinogen-III synthase
- Delta-aminolevulinic acid dehydratase
- Probable uroporphyrinogen-III C-methyltransferase
- Uroporphyrinogen decarboxylase
- Probable oxygen-dependent coproporphyrinogen-III oxidase
- Protoporphyrinogen oxidase
- Ferrochelatase, mitochondrial
- 5-aminolevulinate synthase, mitochondrial
- Siroheme biosynthesis protein met8
- Iron-sulfur assembly protein 1
Sequence:
MPSCTSFPIGTRKSKLAVIQSEIIREELEKHYPHLEFPIISRDTIGDEILSKALFEFKRQLAKSLWTRELEALLVTNQCRILVHSLKDLPSEMPDGMVIACIPKRSCPLDAIVFKAGSHYKTVADLPPGSVVGTSSIRRRALLARNFPHLRFVDIRGNVGTRLAKLDAPDSQFDCLVLAAAGLFRLGLKDRIAQMLTAPFVYYAVGQGALAVEVRADDKEMIEMLKPLQHQETLYACLAERALMKRLQGGCAIPIGVQTDVLAISNSSYRISLLGTVLSADGLRAAFGNAEAVVSSEEEAEELGITVALALLKNGAGPILEEHQRSSDSEESLKNY
Protein: Protein MHF2 homolog (AtMHF2) (Q8L7N3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts in the same pathway as FANCM to restrain class II meiotic crossing over (CO), and acts with FANCM during meiosis to repair interstrand cross-links (ICLs).
Subcellular location: Nucleus {ECO:0000305|PubMed:25038251}.
Interaction partners:
- Protein MHF1 homolog
- DEAD-box ATP-dependent RNA helicase FANCM
- E3 ubiquitin-protein ligase CCNB1IP1 homolog
- ATPase family AAA domain-containing protein FIGL1
- ATP-dependent DNA helicase Q-like 4B
- ATP-dependent DNA helicase Q-like 4A
- DNA mismatch repair protein MSH5
- Protein SHORTAGE IN CHIASMATA 1
- Fanconi-associated nuclease 1 homolog
- Crossover junction endonuclease MUS81
Sequence:
MDANNTFDSDLIHAIFKHIWARRFRERERSDAIDATEAEVALGTTKKNRLASANANALKLSCELLKSFVSEAVQRAAIIAEAEGMEKIEATHLERILPQLLLDF
Protein: Fibromodulin (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) (Q06828)
Organism: Homo sapiens (Human)
Function: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- Transforming growth factor beta-1 proprotein
- Biglycan
- Aggrecan core protein
- Transforming growth factor beta-3 proprotein
- Decorin
- Fibronectin
- Lumican
- Elastin
- Cartilage oligomeric matrix protein
- Mimecan
Sequence:
MQWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI
Protein: Putative transcriptional regulator HVO_1357 (Bacterioopsin activator-like protein) (Receiver/bat box HTH-10 family transcription regulator) (D4GXP4)
Organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Function: May be part of a signal-dependent gene regulation cascade that is relevant to swimming motility. May be involved in the transcription regulation of target genes.
Interaction partners:
- histidine kinase
Sequence:
MVTERSARESPEQRAAEQVVLVVDDDEDLADTCRYWLDGERFAVETAYGGEEALHRLDDTVDVVLLDRRMPNVTGDDVLEEIRERGLDCRVAMMTAVEPDTDIVEMPFDAYLVKPVSESEVKETVEELLVRSGFESGVREYFALESTEAALDSRDVEELREPEALSDLRSRLEAVRAEHEAAIRNREAQLDRLNRTNELLRDVDRALIDARTRDEIEQTVCDVVADAHEAAVVLRRTAAGTLRCTAAAGHGLDPAGVDLDFVDEAFGVDGAAEDGFVFEDIPGAHRAAVLGDDADDLDAVSALCVSIDYRETMYGALVVYDETDGFDDESAGLFSDLGATVGNGINATQSKRLLNGDSVVELEFQVGRDAGVLARLSAALDCQLSLDGVTRLDDGLACFISVAGASGCDAVAAAIDAVDVSQARVVADGDEESVVELRTDAEAVLSTAIDHGASVERLTLSEGSGTLTLHVAADADHGALVEAVTTAAAGVSVVAKREVERSVQSADSFRRALDSKLTDRQRTVLETSLVSGYFEWPRGSTAEEVADSLGISPPTLHEHLRTAERKLIETYFDELNQAPADD
Protein: Rootletin, isoform D (Rootletin, isoform E) (Rootletin, isoform F) (Q9VCD1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Centrosomal protein 135kDa, isoform B
- Nimrod A, isoform E
- Spindle assembly abnormal protein 6 homolog
- Transcription elongation factor SPT5
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB2
Sequence:
MQAYRDNFKQTPCPSAVDLQAAGPAHQSATASRLPFSRSQRGRDPSASGASVSASVAGGLTPRMMSPGPPGAGGGGGGGVSGGGSGDPSALLRQNQELRQRLADESHSYRRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETIKPTAGVGPKLTTGPTNQVLCSTSLTLGQSSLPCSSSLDSPPPSCSRDYVDDVLVTGGGAGAAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINCVGKDINGSNATVAFAVQQAKRAADDELKQSQRSNDELQNQLATLKVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAALASRYSDEIERLNNSMREIAQAVVQDAENADREADAEVTGGVMQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAKWNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDRAEKSNSFYGGAAESGEFDSNRYDVGGGNAGGGSFNCGLDHSVIEQETRDLRLKVRRLETLLAEKESELARCKARMNDSAKCHDGLDGDRYRSAQMHAEKLLDAREQSHRQQVLRLENQISMLREQLAQEAKRRQQYILRSSKANREMQHLRSTLGDSLRNVSQHPVDPHLLESESRRLDSAVSMSLPPSSCRDYDRD
Protein: BBSome complex member BBS5 (Bardet-Biedl syndrome 5 protein homolog) (Q7ZWB7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for ciliogenesis.
Subcellular location: Cell projection, cilium membrane {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000250}.
Interaction partners:
- Bardet-Biedl syndrome 1.
- Bardet-Biedl syndrome 9.
- Bardet-Biedl syndrome 7 protein homolog
- BBSome complex member BBS2
- BBSome-interacting protein 1
- Tetratricopeptide repeat domain 8.
- Bardet-Biedl syndrome 12
- Bardet-Biedl syndrome 10.
- Leucine zipper transcription factor-like 1.
- BBSome complex member BBS4
Sequence:
MASVLDALWEDRDVRFDITAQQMKTRPGEALIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSVGYNCIINITTRTANSKLRGQTEALYILTKSNNTRFEFIFTNVVPGSPRLFTSVIAVHRAYETSKMYRDLKLRGALIQNKQLRLLPQEQVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNESFNVSIPYLQIRSIRIRDSKFGLALVIESSQQTGGYVLGFKIDPMDKLQDAVKEINSLHKVYSANPIFGVEYEMEEKPQPLEELTVEQPPDDVEIEPDEHTDAFTAYFADGNKQHDREPVFSEELGLAIEKLKDGFTLQGLWEVMG