wanglab/gogpt-training-data huggingface dataset:
Protein: Centrosomal protein of 72 kDa (Cep72) (Q9D3R3)
Organism: Mus musculus (Mouse)
Function: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (By similarity). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9P209}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000250|UniProtKB:Q9P209}. Note=Localizes to the centrosome and centrosome-surrounding particles throughout the cell cycle. These particles disappear after microtubules are depolymerized using nocodazole, suggesting that CEP72-associating particles localize in a microtubule-dependent manner (By similarity). {ECO:0000250|UniProtKB:Q9P209}.
Interaction partners:
- Serine/threonine-protein kinase PLK1
- Pericentriolar material 1 protein
- Centrosomal protein of 290 kDa
- HAUS augmin-like complex, subunit 6
- Centrosomal protein of 131 kDa
- Coiled-coil domain-containing protein 14
Sequence:
MAPGQRLVLCEETVRERSGLGPHRDLAELRSLSIPGTYQEKITHLGNSLMHLTALKSLDLSRNSLVSLEGIQYLVSLESLNLYYNCISSLAEVFRLHTLLELQDVDFRLNPVVKNESDYRLFVVHMLPKLRQLDDRPVRESERKASQLHFAPEDSLNSKENFSTTLTVGRPHHLRNRCTETSAKKCLVMDADDEAVLNLIAECEWDLSNPPGNMSSSQKEHEADLHYAQESRHLLSPLSIQHQCGDSARRGHEKKKVTSRGCPGHSPQDQLCGELPLQHGLPEACHMHVQHARITSQPDSVDVEDCASSAQKSSLSSQKTVNPLPVPEKYRKRRMPGGRFQVPSDRECLSFLERADGPSSLEDSLSRQDGLEGQSQVALSHSEALEAEERTSHGTSDPRVLSPKLCSAAVPERRSTLEVALLEALLDLIDRCSSGSGSLHGNEAFLAQAKHVLSSLQEFTATRDSSALEKEGIGYLSLENKTLQSRLAEQQQQYTATVTKMTAELNNTKRELDTLRQHLDKSLEENSHLKSLLYNVKKEVKTADTSTALTLQITGLQASMKQLSGEVVELKQHVEHYDKIQELTQMLQESHSSLVSTNEHLLQELSRTRAQHRAEVEQMRWSFQEFKKTTALIPHRSSRRGGRQSC
Protein: Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1) (A0A2R8YFU2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU369118}.
Interaction partners:
Sequence:
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
Protein: DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1) (Inhibitor of differentiation 1) (P41135)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus.
Interaction partners:
- ETS proto-oncogene 2, transcription factor
- Ras-related protein Rap-1b
- Ras-related protein Rap-1A
- Transcription factor E2-alpha
- Myoblast determination protein 1
- Transcription factor COE2
Sequence:
MKVASSSAAATAGPSCSLKAGRTAGEVVLGLSEQSVAISRCAGTRLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVATAGGRGLPVRAPLSTLNGEISALAAEVRSESEYYIILLWETKATGGGCPPYFSGA
Protein: Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13) (P15144)
Organism: Homo sapiens (Human)
Function: Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:2564851, ECO:0000269|PubMed:9056417}; Single-pass type II membrane protein {ECO:0000305|PubMed:1350662}. Note=Also found as a soluble form. {ECO:0000269|PubMed:7902291}.
Interaction partners:
- Reticulon-4 receptor
- Cytosol aminopeptidase
- T-cell antigen CD7
- 14-3-3 protein sigma
- Glutathione hydrolase 6
- Myeloid cell surface antigen CD33
- Low affinity immunoglobulin gamma Fc region receptor III-A
- Glutathione hydrolase 7
- Glutathione hydrolase 1 proenzyme
- Glutathione hydrolase 5 proenzyme
Sequence:
MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK
Protein: DNA-binding transcriptional repressor Mlc (Making large colonies protein) (Membrane linked control) (P50456)
Organism: Escherichia coli (strain K12)
Function: Transcriptional repressor that regulates the expression of proteins that are part of the phosphotransferase system for sugar uptake. Regulates the expression of malT.
Subcellular location: Cytoplasm {ECO:0000305}. Note=Interaction with dephosphorylated PtsG leads to the sequestration of Mlc in the inner membrane fraction. {ECO:0000269|PubMed:11032803, ECO:0000269|PubMed:12529317, ECO:0000269|PubMed:18319344}.
Interaction partners:
- PTS system glucose-specific EIICB component
- Mlc titration factor A
- DNA-binding transcriptional dual regulator CRP
- D-allose kinase
Sequence:
MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAPASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALRDLSSKLVVEESQELALKDDLPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTENGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQVVIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILELAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFNPQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKDAMYNGSLLIRLLQG
Protein: Venom allergen-like protein (Q19348)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MAVLAVVLLLACLERAVAQTFGCSNTKINDQARKMFYDAHNDARRSMAKGLEPNKCGLLSGGKNVYELNWDCEMEAKAQEWADGCPSSFQTFDPTWGQNYATYMGSIADPLPYASMAVNGWWSEIRTVGLTDPDNKYTNSAMFRFANMANGKASAFGCAYALCAGKLSINCIYNKIGYMTNAIIYEKGDACTSDAECTTYSDSQCKNGLCYKAPQAPVVETFTMCPSVTDQSDQARQNFLDTHNKLRTSLAKGLEADGIAAGAFAPMAKQMPKLVKYSCTVEANARTWAKGCLYQHSTSAQRPGLGENLYMISINNMPKIQTAEDSSKAWWSELKDFGVGSDNILTQAVFDRGVGHYTQMAWEGTTEIGCFVENCPTFTYSVCQYGPAGNYMNQLIYTKGSPCTADADCPGTQTCSVAEALCVIP
Protein: Receptor-like protein kinase 5 (EC 2.7.10.1) (EC 2.7.11.1) (Protein HAESA) (P47735)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates that controls floral organ abscission. May interact with the 'INFLORESCENCE DEFICIENT IN ABSCISSION' (IDA) ligands family.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10640280}; Single-pass type I membrane protein {ECO:0000269|PubMed:10640280}.
Interaction partners:
- Protein IDA
- Protein IDA-LIKE 1
- Somatic embryogenesis receptor kinase 1
- ADP-ribosylation factor GTPase-activating protein AGD5
- Polygalacturonase ADPG2
- ADP-ribosylation factor GTPase-activating protein
- Homeobox protein knotted-1-like 1
- Protein CLAVATA 3
- Homeobox protein knotted-1-like 2
- Protein IDA-LIKE 4
Sequence:
MLYCLILLLCLSSTYLPSLSLNQDATILRQAKLGLSDPAQSLSSWSDNNDVTPCKWLGVSCDATSNVVSVDLSSFMLVGPFPSILCHLPSLHSLSLYNNSINGSLSADDFDTCHNLISLDLSENLLVGSIPKSLPFNLPNLKFLEISGNNLSDTIPSSFGEFRKLESLNLAGNFLSGTIPASLGNVTTLKELKLAYNLFSPSQIPSQLGNLTELQVLWLAGCNLVGPIPPSLSRLTSLVNLDLTFNQLTGSIPSWITQLKTVEQIELFNNSFSGELPESMGNMTTLKRFDASMNKLTGKIPDNLNLLNLESLNLFENMLEGPLPESITRSKTLSELKLFNNRLTGVLPSQLGANSPLQYVDLSYNRFSGEIPANVCGEGKLEYLILIDNSFSGEISNNLGKCKSLTRVRLSNNKLSGQIPHGFWGLPRLSLLELSDNSFTGSIPKTIIGAKNLSNLRISKNRFSGSIPNEIGSLNGIIEISGAENDFSGEIPESLVKLKQLSRLDLSKNQLSGEIPRELRGWKNLNELNLANNHLSGEIPKEVGILPVLNYLDLSSNQFSGEIPLELQNLKLNVLNLSYNHLSGKIPPLYANKIYAHDFIGNPGLCVDLDGLCRKITRSKNIGYVWILLTIFLLAGLVFVVGIVMFIAKCRKLRALKSSTLAASKWRSFHKLHFSEHEIADCLDEKNVIGFGSSGKVYKVELRGGEVVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWCCCSSGDCKLLVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKSSNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTDSELGDKDMAKWVCTALDKCGLEPVIDPKLDLKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEVSGAVPCSSPNTSKRSKTGGKLSPYYTEDLNSV
Protein: Amyloid beta precursor like protein 1 (A0A8I6AD03)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MGPSSPTTRGQGRRRGPPPLPLLLPLSLLLLRAQLAVGNLAGGSPSAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLLDPQRVLEYCRQMYPELHIARVEQAAQAIPMERWCGGTRSGRCAHPHHEVVPFHCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPATPNPSGMAVGDPSTRSWPLGGRAEGGEDEEEVESFPQPVDDYFVEPPQAEEEEEEEEERAPPPSSHTPVMVSRVTPTPRPTDGVDVYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADSQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDPPQAERVLMALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVQTHLQVVQERMNQSLGLLDQNPHLAQELRPQIQELLHAEHLGPSELEASVPGSSSEDKGSLQPPESKDADAPVTLPKGSTDQESSSSGREKLTPLEQYEQKVNASAPRGFPFHSSDIQRDELAPAGTGVSREALSGLLIMGAGGGSLIVLSLLLLRKKKPYGTISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
Protein: Immunoglobulin alpha Fc receptor (IgA Fc receptor) (CD antigen CD89) (P24071)
Organism: Homo sapiens (Human)
Function: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Subcellular location: [Isoform A.1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform A.2]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform A.3]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform B]: Secreted.; SUBCELLULAR LOCATION: [Isoform B-delta-S2]: Secreted.
Interaction partners:
- High affinity immunoglobulin epsilon receptor subunit gamma
- High affinity immunoglobulin gamma Fc receptor I
- Immunoglobulin heavy variable 4-38-2
- Polymeric immunoglobulin receptor
- Low affinity immunoglobulin gamma Fc region receptor II-a
- High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
- TYRO protein tyrosine kinase-binding protein
- Low affinity immunoglobulin gamma Fc region receptor III-B
- Low affinity immunoglobulin gamma Fc region receptor III-A
- Transferrin receptor protein 1
Sequence:
MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCK
Protein: EGF-like domain-containing protein (Q54L31)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Latrophilin receptor-like protein A
Sequence:
MGRYFVFLLVFILFFNGFNSQIHKDDYSCLNKLAVKILNLSLYSLNSTTKQYNFCSKVNKNEINCNSDGRITGIQVVHFKKINLLSPNDFICFPFLKSIGVESFVISKNFLYGPFPDSLDERVFLLNGDLLSIFDVDTEIGFNNTIKRTEIDILRVNGGVATSLNTTVYMSTISHFKNIEFIYGTAAITNKTNFIIENDLNENKKSSFKDFTSYCSNIPPLSYNNGTIDFVELTFLPSFDKESVSNFSSYSNVLDIYLYSWDPNQVFPFPLGLSNIPPGNKLIYLTIDSPGNLFNFNGKFPFSSFYKNLEHFALNDGNFSELPKLEDVFKEKITVINLNNNSIGGNVQTTLDFGKLPNLKVLKLKNNKLTGSIDESWCRVNFDISNNLISGEAPGCVICHVPDHHPRIRGINFTNWDPKPPCTSIIPNLMYDNSSDLLLLYGQDIGFSPMDMYILDISYKFSFSCDMPGYPEIYNTQFCLKYISTDGPNPYSFNITYQHLPPGSKTTFELAAYNMFLPLVNTAILDYSNESLTIAGRYFSYNKTVINIQVNGKTCNIESCDFNEIKCNFSNDNNNNSNFNGSNVFVQIMNVSSEICISKCNDDVPYECEFKFERCNCSEGWEGDNCETLKRCPNDCSGAGICNHITGICLCNSGRIQDDCSVLGFECKSDCLNGSKCNYAIGKCDCILGWEGDDCSSELSSSEPSSSSELSSSEPSKSNKIILLSVLLPSLALLGLILSF
Protein: Lysophospholipase (EC 3.1.1.5) (A0A1D8PU17)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- PNPLA domain-containing protein
- Glycerophosphocholine phosphodiesterase GDE1
- Lysophospholipid acyltransferase
Sequence:
MELLNIIVVLFLSIYTNPIIAWSPTDSYAPGEIQCPSNSSLTRNADSLSPQEQEWLKGRSPIANENLISFLNSANMTDFDPESFINGLNRSIKIGLSFSGGGYRAMLNGAGQLAALDNRTRGGFESGLGGLLQASTYLVGLSGGNWMVGTIAYNNFTSVQHILDQDSIWDLSHSIMNPGGWNIKKTYNYYKNISDALDDKRNAGFDVSITDTWGRALSHQFFPGLDDGGDALTWSTLQDVDVFKNYEMPFPIVVADGRTPGTYVISGNSTVFEFNPFEMGSWDPAVYQFSQVKYLGTEVKDGKPSSNGKCIGGFDNAGFIMGTSSSLFNQFILQINTTSLSSTIKSLLTSILQDLSNDDNDIAVYKPNPFKDSDVAGSKSIASNDTLYLCDGGEDLQNIPLYPLLQEQRQVDVIFAYDNSADTNQYWPNGASMVASYQRQFGNQSNGTSFPYVPDVATFVNSNLTAKPTFFGCDAKNLTSLTTTQNKTSVYDIPLLVYTANRPFSYWSNTSTFQMKYETKERNAIIQNGFEVATRMNLTLDNEWKACVGCAIIRRQQERQGLEQSDQCKKCFEKYCWDGKLTTNADAININFTTEGTTNDTESMKVNSGVLTSVSWSLWAMMLAALSVFILG
Protein: Feruloyl-CoA synthase (EC 6.2.1.34) (Feruloyl coenzyme A synthetase) (Feruloyl-CoA synthetase) (Q9EY88)
Organism: Amycolatopsis sp
Function: Catalyzes the formation of (E)-feruloyl-CoA, AMP and diphosphate from (E)-ferulate, CoA and ATP. Involved in the degradation pathway of lignin-derived aromatic compounds of plant cell walls. Catalyzes the first enzymatic step in the conversion of ferulic acid into high value compound vanillin.
Interaction partners:
Sequence:
MRNQGLGSWPVRRARMSPHATAVRHGGTALTYAELSRRVARLANGLRAAGVRPGDRVAYLGPNHPAYLETLFACGQAGAVFVPLNFRLGVPELDHALADSGASVLIHTPEHAETVAALAAGRLLRVPAGELDAADDEPPDLPVGLDDVCLLMYTSGSTGRPKGAMLTHGNLTWNCVNVLVETDLASDERALVAAPLFHAAALGMVCLPTLLKGGTVILHSAFDPGAVLSAVEQERVTLVFGVPTMYQAIAAHPRWRSADLSSLRTLLCGGAPVPADLASRYLDRGLAFVQGYGMTEAAPGVLVLDRAHVAEKIGSAGVPSFFTDVRLAGPSGEPVPPGEKGEIVVSGPNVMKGYWGRPEATAEVLRDGWFHSGDVATVDGDGYFHVVDRLKDMIISGGENIYPAEVENELYGYPGVEACAVIGVPDPRWGEVGKAVVVPADGSRIDGDELLAWLRTRLAGYKVPKSVEFTDRLPTTGSGKILKGEVRRRFG
Protein: Metacaspase-1 (EC 3.4.22.-) (PfMCA1) [Cleaved into: Large subunit p20; Small subunit p10] (Q8IDF3)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Cysteine protease that cleaves specifically after arginine or lysine residues. May play a role in apoptosis.
Interaction partners:
Sequence:
MEKIYVKIYELSGLEDKDNFSCYIKIYWQNKKYKSCILQKNPYKFNEIFLLPIDIKNNVKDEKNNILSIEVWSSGILNNNKIAYTFFELDHIRRERISSEKINLIDVVKKCTLQISVHIINNNQDILFCNIKDIFGNNKNDKEIHDAILKYGGNERHIIKELRKEKEIGQYNNIYFNDYVNVLNTDPSQNYIYNDMPKITPNNIYNNMNNDQTNHTYLKAPNSLYNNENTIYSSNVHYSTYMNNSPTYKNSNNMNHVTNMYASNDLHNSNHFKPHSNAYSTINYDNNNYIYPQNHTNIYNRASPGSDQTLYFSPCNQKKALLIGINYYGTKYELNGCTNDTLRMKDLLVTKYKFYDSSNNIVRLIDNEANPNYRPTRRNILSALMWLTRDNKPGDILFFLFSGHGSQEKDHNHIEKDGYNESILPSDFETEGVIIDDELHKYLIQPLNEGVKLIAVVDSCNSGSSIDLAYKYKLKSKKWKEDKNPFHVICDVTQFSGCKDKEVSYEVNTGQIAPGGSLVTAMVQILKNNMNTPSIITYEYLLHNIHAHVKQHSNQTVTFMSSQKFNMNRLFDFEHIIKNKNNQLGQIINKYIEKNKSKNKNKLKHELKNLFFF
Protein: Uncharacterized protein C18H10.07 (O60138)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- U1 small nuclear ribonucleoprotein usp102
- Pre-mRNA-processing factor 31
- Uncharacterized protein C30D11.14c
- Pre-mRNA-splicing factor brr2
- Peptidyl-prolyl cis-trans isomerase cyp3
- LSM complex subunit lsm6
- U2 snRNP component prp10
- U4/U6.U5 tri-snRNP-associated protein snu66
- Large ribosomal subunit protein eL30B
- Pre-mRNA-splicing factor sap114
Sequence:
MADYWKSIPKYYCKYCQIFVKDTPFARRSHEQTYKHQDAIKKVMDDIHRSNLLRQELEKNLSIPKSATATTASAVSSELASYEKPKKEHPKLRPSKKKATLDDWDIPTSSTETDTISTTHTSYIPTLLAKQEENEETKETTTNKNESLPGTSLKRNREIIEKEERSSFHFRVKPKNLDKVPKLAENEGNKSLESKESNENKVVFKKKKSGKLRTKSSLKEYDQS
Protein: Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) (P00954)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the attachment of tryptophan to tRNA(Trp). Amino acylates tRNA(Trp) with both L- and D-tryptophan, although D-tryptophan is a poor substrate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00140}.
Interaction partners:
- Phosphoglycolate phosphatase
- Tyrosine--tRNA ligase
- Ribulose-phosphate 3-epimerase
- Arginine--tRNA ligase
- Leucine--tRNA ligase
- Methionine--tRNA ligase
- Valine--tRNA ligase
- Isoleucine--tRNA ligase
- Glutamate--tRNA ligase
- Histidine--tRNA ligase
Sequence:
MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDIAQRFNALYGEIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP
Protein: Nop14-like protein (Q587G6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- AATF leucine zipper-containing domain-containing protein
- BING4 C-terminal domain-containing protein
- Uncharacterized protein
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 6 N-terminal domain-containing protein
- KRR1 small subunit processome component
- Bms1-type G domain-containing protein
- rRNA biogenesis protein, putative
- U3 small nucleolar ribonucleoprotein protein MPP10, putative
- RNA 3'-terminal phosphate cyclase-like protein
Sequence:
MTLSLHAFPFSTLGARFFFPFLCLVMRASSANARLVQRHERQKAQSAAKASSARFNAKQSRFQLRQEEAQVRNEIQKEPLPISSAVTAPNRDQTSTFSRFDRPPARASTAMVATTNTTTTTTATFGLAPVRRTTNANAMGHVGTRTSRRAARFRLEDAEGTHSSAVGDNNMPEVGGLLGTVRRPRQAEVDDDASGDAGRKKTRVEKFQEVMANSKEHRAHLQREREQRSVQTKAIDQEFNNVLHLLERRDKVKEDREAFNAAGTPEVRALLQSFRTNHVAKVLSLRSDGSYTVAPLSAPDEKAANVSTTTATAATSVTAEGTKQETTSFLDSADMELLRKVRSGVAEREVVPGAKESDIAMGSARPSRSNVVDEEANAEADEFDRMMQSMRLETRRAIAGDRTLTEEEQKQKLLEQELLEADRGAMPTISHNREQLTRAELLSRGGDFPEMGDDDGSVPEGELEDNLDISTAYDSDGASQRSDDDGTGNYDGKEAYEGDDVHQELGVTGAGAGGLGALEILLSEVETLSRSGNGTRSARAARGEAYHALLIRLYRYAQSHVLHTAQTFRALLIEAQRSFLRHGSLDRATLLLLHTTSRIFPMTDYRHAVTTPFFIFLCSTLLQMKLKTVAQARDYAVLAGLLCSCMLQGGKFCAEAIIAPLNLIALQVPRSVLEPARLQGICVPFPLVGRGDTEVALLLTNEKESLSAPTAHDGDDNVKEGDGTAEAKAANNEEDVDEPLLEGTLAVLETDVSAERIVRYAYRLLSVQADALRNVPAFEYCLAAPFRALHERLTAAAITSTAKRGKGKSSSDSKVMACWKPSPLVQADHEALLEKLTQFTSDARNRRTPLAMRNFRPRPIRQFDPLLHEREDIGGDANMSTSVLKSEVRQMKRELREDRKRVVRHLQAEANVERRQRERAAAEVEAQRERKYRELMGSLQAQQHIMKTVDGLQAKARSKKRRSISGLPGKAEDNTDGGGA
Protein: Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) (Q6FUP6)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Interconversion of serine and glycine.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Aminomethyltransferase
- Glycine cleavage system P protein
- Methylenetetrahydrofolate dehydrogenase [NAD
- Phosphoribosylglycinamide formyltransferase
- Candida glabrata strain CBS138 chromosome A complete sequence
- Glycine cleavage system H protein
- alanine--glyoxylate transaminase
- Tryptophan synthase
- phosphoserine phosphatase
- thymidylate synthase
Sequence:
MPYALSDKHLKMVSGHLSETDPEVEQIIKDEVDRQKHSIDLIASENFTTTSVFDALGTPLCNKYSEGYPGARYYGGNEHIDRIERLCQQRALEAFHVTPDRWGVNVQTLSGSPANLQVYQALMKPHERLMGLYLPDGGHLSHGYATENRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKILVAGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFFRRGIRSVNQKTGKEIPYDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEFKEYQTQVLKNAKALENEFQTLGYRLVSNGTDSHMVLVSLREKGVDGARVEYVCEKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVRYIDQAVKFAEQTQSSLPKEANKLKDFKAKVDEIADQLAPLKKEIYDWTAEYPLAV
Protein: Glideosome associated protein with multiple membrane spans 1 (Q8IE80)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Inner membrane complex sub-compartment protein 3
Sequence:
MFFTYVVRPGEAPEGRGPQFEPFWDFFMNFNLRVGFLIQFISYILLVGAITIIGKNPLGMLNFLRALPGSVGTAPMPLVLFSIGGFLMGTLLIMSFLQLTEDDSSIKQSRGYRAGTKFLLQATSMGTVSWSLSLICLMASSYYFDDPWMEEKIGAGSSWILYFSSRLIDAFCLFLYGSGCFFLEVYHSEGAGEAWGWLCGMCFIATSFVEVLALTLFNTPLFSSLDWFYCLFLGLSLFFSVIWGLLFEPISHRYDVKLTQSAMRNEYYKSRNAMAYYGPAVVTANGELDIEASTENIAACKQC
Protein: Uncharacterized protein (Q582A8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRRGFFLRARPDFVAALLTQGRLVDVLLFQHFGAEPAITDTNDNNGIGPAATKKDGNTDGVKVNASDVEKSSGKAAELTTAKSPVTAPSQRSLLRERCDAVRTATKRSAHPVMWPVDVGTAATEWRAPPNSQDHVRVALGSDGSNEPGRKVVLHGSFIAIAAPGSIPKTMQLLASQECGKEDQVKGTASNREPLLLSLPMQQAGGHISVSPATGGLCTVTLSGAEAAIVSNSAAAVDAFTAEHNLLAAAASSGMIDRLLEICALHATHAVRHDALLIRNPFVQKALAAMACSRYGIDALTSFVVGCSADDPSQLAKDTNPVDSKENEVGDARHPPLAECVAVSTYAGQALATALQLTREVINGVLQLDPQGGVPHASKPDRLIDYAYAVRMVRDESQILAALSFRGSLQHQRYIAPLLLHTESGLQGAAGSVSKGIGSSLFMRAISAPSDVPRLVSPHVYLRLSANELEGDVATFLKLLREGERRRDAAFIRTTAQYVAEVFASVAVLYRATAALTRTGNNAPRDWLLAQAFCGESAVCRAALLRNFEMSKAARTALLSAGNNSGTIHPVELMNAQPVRKMAKTPTH
Protein: HTH-type transcriptional regulator KmtR (O53838)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Represses expression of Rv2025c and its own expression. Acts by binding to the promoter regions.
Interaction partners:
- Probable cation efflux system protein Rv2025c
- Zinc uptake regulation protein
- Transcriptional regulatory protein EmbR
- Probable hydrogen peroxide-inducible genes activator
- Probable transcriptional regulatory protein
- Uncharacterized HTH-type transcriptional regulator Rv0377
- HTH-type transcriptional regulator VirS
- Probable transcriptional regulatory protein
- Transcriptional regulatory protein KdpE
- HTH-type transcriptional regulator Rv1931c
Sequence:
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQHLAKLRMARLVRTRRDGTTIFYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSVAKASATKDVG
Protein: Regulator of chromosome condensation 1 (C9JQZ4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSPKRIAKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIP
Protein: Transmembrane protein 18 (Q6DGF8)
Organism: Rattus norvegicus (Rat)
Function: Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats (By similarity). Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q96B42}. Nucleus membrane {ECO:0000250|UniProtKB:Q96B42}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glucosamine-6-phosphate isomerase
- Kctd15 protein
- Neuronal growth regulator 1
- Alpha-ketoglutarate-dependent dioxygenase FTO-)-demethylase FTO)
- Protein transport protein Sec16B
- Melanocortin receptor 4
- Mitochondrial carrier 2
- SH2B adapter protein 1
Sequence:
MASPYSVRVFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSAQRYKLQIGHFLCLVVLVYCAEYINEVAAMNWRLFAKYQYFDSRGMFISLVFSAPLLFNAMVIVIMWVRKTLTVMSDLKNLQERRKERKRRRKEE