Protein: Dynein axonemal heavy chain 11 (Axonemal beta dynein heavy chain 11) (Ciliary dynein heavy chain 11) (F1SC07)
Organism: Sus scrofa (Pig)
Function: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q96DT5}. Note=Located in the proximal region of respiratory cilia. {ECO:0000250|UniProtKB:Q96DT5}.
Interaction partners:
Sequence:
MAASVAAQEAHGFRKVPTLSLTPGVGMEAAGLVELEEEEEEEEEEEAAARRARSFVQDARVRFVGGRLEQMLGFPEEKWSQHLESEDNRQILGEFLESPGPACLVFSIAAAGQLATSHQIPRDAKHKLVYIAKKITENTGVNDFSQTVVFGELPASSVGYVTAFLDEILVPIISNKNNHKSWSCFISQDMERHVEVMRNKMHIFRGKMLRRTLLPIPTIAGNIDLDQKYSETRLEPNERTILHVLESVVIKWSHQIQEVVEKDSVQPLLSGLHSNPETELDFWTMRRENLSCIYDQLQAPIVLKMVKILKNKQSSYFPTLRDIFLSVKNALREAQDVELYLRPLRRHIQCLQETEFPQTRVLIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFIDQARAYLSPEHLLKGELEDSLEKVQVVINVFKTFKNSFFNYRKGLASYFMGKKEMKPWDFRSHLVFWRFDKFLDRFMKIEDIFVTTLEFEKLERLEFGGTKGAIFNGQIHEMSEELMELCKVFKQSTYDPSDYNNMEFESEYAMFKSKTVDFDRRLGTILCVALFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSPHYSTLVHMFNAELDMCKQLYNEHVKQIEQGTVVLNKNMPFTSGNIKWAKEVLDRLQMFWSNFASLRYLSLESPDDAVVYQKYTEMTTLLDQFENHVYNEWKSNVEEICDFSLNQPLIRFSAVNGLLSVNFDPKLVAVLREVKYLLMLKKSDIPDSALAIFKKRDTLLKYIGNLELLVQGYNKLRQTLLDVEYPLIKDELRAVDEELQAAATSLTWQDDCLRDIERVKTATSELERRVEHTHDNVRAIQQMMRAWAEGTLLPRREHRRETALTWEDKGDLFMKKYKQIQEDGCKIHSLVEENRRLFKANPSLDTWKIYVEFIDDIVVEGFFQTIMHDLDFFLMNTEKQLKPAPFFQAQMILMPPEILFKPSLEREAGDGFYDLVEEMLCSSFRMSAQMKRVAAHLGVANYQNDMDNMLGLAEVRQEIMKRVADVISKVLDFRSTLDMYAYLWVDDRAEFMKHFLLYGHIVSSEETDPLADEDIPEQSPTLEQFKEQIDIYEALYVQMSKFDDFRVFDSWFKVDMKPFKVSLLNIIRKWSWMFQEHLLRFVIDSLNELQEFIKETDAGLQRELSEGDHDGLVDIMGHLLAVRSRQRATDELFEPLKETITLLETYGQKMPEQIYVQLEELPERWETTKKIAATVRHEVSPLQNAEVTLIRKKCISFDEKQAEFRERFRLCAPLGFNAENPYTVLDKAHQELEALEEEVLQMQESTHVFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQINVEQMDVELRRFAKEIWSLDKEVRVWDAYSGLEGTVKDMTTSLRAVAELQSPALRDRHWHQLMKAIGVKFSINEAMTLADLLALQLHQVEEDVRSIVDKAVKELGTEKVINEIIQTWATMEFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVTSWQHKLNTADSAIFTWMEVQRTWSHLESIFVCSEDVRIQLKEDARRFDEVDVEFKELMFRTAKIKNVLQATCRPNLCEKLKDLQYRLSLCEKALAEYLETKRVAFPRFYFISSADLLDILSKGAQPAQVTRHLSKLFDSIADLRFEDDQDVSASRAVGMYSKEKEYVPFSATCECTGHVETWLLQLEQIMKETVRHSITEAIAAYEDKPREVWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLIALLLGELLPGDRQKIMTICTIDVHARDVVAKLISQKVRSPQAFAWLSQLRHQWEDTRKHCLVHICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEIMLVAEGFVDARSLAHKFITLYTLCRELLSKQDHYDWGLRAVKSVLVVAGSLKRGDKSRPEEQVLMRALRDFNMPKIVTDDIPVFLGLVSDLFPALDVPRRRAPHFEQMVRQSTVELRLQPEENFILKVVQLEELLAVRHSVFVIGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGNVVYSLIGLFSSLLREQANLRQDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPSMRLLFEIHHLRTATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTVCTLLECLLTPENVPSDSPKDVYEVYFVFACVWAFGGTLSQDQLSGCQAEFSRWWHKEMKAVKFPSQGTIFDYYLDHKTKKFLPWADKIPKFTMDPEVPLQRVLVHTSETTRLRYFIELLLEKGQPLMLVGNAGVGKTVFVGDMLTSLSEAYIVSRVPFNYYTTSAALQRILEKPLEKKAGRNYGPGGNKKMVYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVRLKEIHGCQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSMDALNTIYSQILSSHFQHQAFGPSVLRSGPALIQATIAFHQTMTHNFLPTAIKFHYLFNLRDLSNVFQGILFASSECLKGPNDLIQLWLHESYRVYGDRLIDTKDCNLFQKKMLETANKYFEGVDSQLLLQQPLIYCHFANGKEDLCYMPVKDWEVLKTFLTEALDNYNDLNAAMPLVLFEDAMQHVCRISRILQTPQGSALLIGVGGSGKQSLSRLAAYICGLEVFQVTLTQGFGIQELRVDLANLYIRTGAKNLPTAFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIRNEVRSLGMVDSKENCWKFFLARARLHLKIILCFSPVGHTLRDRARKFPALVNCTAVDWFHAWPREALVTVSRRFIEETRGIEPLDKDSISLFMAHVHTSVNEMSTRFYQNEGRHNYTTPKSFLEQISLFKNLLKKKQKEVSQKKEHLVNGIQKLKTTASQVGALKARLASQEAELQLRNQDAEALIAKIGLQTEKVSREKAIADAEERKVTAIQTEVSQKQRECEADLLKAEPALVAATAALNTLNRVNLTELKVFPNPPNAVTNVTAAVMVLLAPQGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEQYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRHALAQANLELATATEKLEAIRKKLADLDRNLSRLTASFEKAIAEKVRCQEEVNQTNKTIKLANRLVKELEVKKIRWGQSIKSFEAQEKTLCGDILLTAAYVSYVGPFTQQYRQELVDCMWVPFLHWKVSIPMTEGLDVIAMLTDDATIATWNNEGLPNDRMSTENAAILTHCQRWPLMIDPQQQGIKWIKKKYGTDLKVTHLGQKGFLNDIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGKYIKIGDKECEFNHNFRLILHTKLANPHYKPELQAQTTLLNFTVTQDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDCKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLETAKATAAEIERKVIEARENERKINEARERYRPVAARASLLYFVINDLRKINPIYQFSLKAFNLLFQRAIEQADKVEDAQGRISALTESITHAVFLSTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTYPSPVDFLTPQAWSALKAVALREEFRGLDRDVEGSAKQWRRWAESECPEKEKLPQEWKKKSLIQKLIILRALRPDRMTYALRNFVEEKLGAKYVERTRLDLIKALEESSPACPVFFILSPGVDALKDLEILGKRLGFTSDLGTFHNVSLGQGQEMVAEVALEKASKGGHWVMLQNVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPHEHVIPPGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEACSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFSPRDLTICAHVLYNYLEANPHVPWEDLRYLFGEIMYGGHVTDEWDRKLCRVYLEEFMNPSLIDDELMLAPGFAAPPNLDYSGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEIQPKNALSNEELGQSTEDKVKNVLEDILEKLPEEFNMAEIMQKNPNRSPYVLVCFQECERMNILLQEIRVSLQRLDLGLKGELTLSPDMEAQQSALSYDAVPDTWSKVAYPSTYGLAQWFNDLLLRCRELDTWTQDLALPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKMCLTIDVTKKMKEDYGHAPREGAYLHGLLLEGARWDSQSGTIVDAHLKELRSAMPVIFAKAIPMDRQETKHTYECPVYRTKMRGPNYVWTFRLKSKEKTAKWVLAGVALLLEA