wanglab/gogpt-training-data huggingface dataset:
Protein: Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed] (Q16543)
Organism: Homo sapiens (Human)
Function: Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9482106}.
Interaction partners:
- Heat shock protein HSP 90-alpha
- Heat shock protein HSP 90-beta
- Cyclin-dependent kinase 4
- Prostaglandin E synthase 3
- Serine/threonine-protein phosphatase 5
- Stress-induced-phosphoprotein 1
- RAC-alpha serine/threonine-protein kinase
- Heat shock 70 kDa protein 4
- RAF proto-oncogene serine/threonine-protein kinase
- Serine/threonine-protein kinase B-raf
Sequence:
MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV
Protein: Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) (P62517)
Organism: Escherichia coli (strain K12)
Function: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Glucans biosynthesis protein G
- Glucans biosynthesis protein D
- Cell division protein FtsZ
- Glucans biosynthesis protein C
- Glycerol-3-phosphate acyltransferase
Sequence:
MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWAREDDSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRFWDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTILPYQGWALINPMDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQLLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAKHFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRRWGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPELAIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLFHTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLFWLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQRSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRRLVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ
Protein: Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein) (O54960)
Organism: Rattus norvegicus (Rat)
Function: Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.
Subcellular location: Cell projection, filopodium {ECO:0000269|PubMed:33523862}. Cell projection, podosome {ECO:0000269|PubMed:33523862}.
Interaction partners:
- Nitric oxide synthase 1
- Dexamethasone-induced Ras-related protein 1
- Disks large homolog 4
- Alpha-1-syntrophin
- Synapsin-1
- DEAD
Sequence:
MPSKTKYNLVDDGHDLRIPLHNEDAFQHGISFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVSTATAEETDIDAVEVPLPGNDILEFSRGVTDLDAIGKDGGSHIDTTVSPHPQEPMLAASPRMLLPSSSSSKPPGLGTGTPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQSTMGSQDSLLEITFRSGALPVLCESTTPKPEDLHSPLLGAGLADFAHPVGSPLGRRDCLVKLECFRFLPAEDNQPMAQGEPLLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDSLDDEIAV
Protein: Ras-related GTP-binding protein B (Rag B) (RagB) (EC 3.6.5.-) (Q5VZM2)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9394008}. Lysosome membrane {ECO:0000269|PubMed:20381137}. Note=Recruited to the lysosome surface by the Ragulator complex. {ECO:0000269|PubMed:20381137}.
Interaction partners:
- Ras-related GTP-binding protein A
- Regulatory-associated protein of mTOR
- Ragulator complex protein LAMTOR4
- Ras-related GTP-binding protein C
- Serine/threonine-protein kinase mTOR
- Ragulator complex protein LAMTOR2
- GATOR2 complex protein WDR24
- Ras-related GTP-binding protein D
- Ragulator complex protein LAMTOR1
- Neutral amino acid transporter 9
Sequence:
MEESDSEKTTEKENLGPRMDPPLGEPEGSLGWVLPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR
Protein: Straight fiber protein pb4 (pb4) (Tail protein pb4) (Q6QGF0)
Organism: Escherichia phage T5 (Enterobacteria phage T5)
Function: Probable central straight fiber at the tail tip.
Subcellular location: Virion {ECO:0000269|PubMed:24198424, ECO:0000269|PubMed:36961893}. Note=Component of the tail (PubMed:24198424, PubMed:36961893). Located under the baseplate and the BHP-pb3 trimer (PubMed:24198424, PubMed:36961893). {ECO:0000269|PubMed:24198424, ECO:0000269|PubMed:36961893}.
Interaction partners:
Sequence:
MISNNAPAKMVLNSVLTGYTLAYIQHSIYSDYDVIGRSFWLKEGSNVTRRDFTGIDTFSVTINNLKPTTTYEVQGAFYDSIIDSELLNAQIGINLSDKQTFKMKSAPRITGARCESEPVDVGVGAPIVYIDTTGEADYCTIELKDNSNANNPWVKYYVGALMPTIMFGGVPIGSYKVRISGQISLPDGVTIDSSGYYEYPNVFEVRYNFVPPAAPINIVFKAARIADGKERYDLRVQWDWNRGAGANVREFVLSYIDSAEFVRTGWTKAQKINVGAAQSATIISFPWKVEHKFKVSSIAWGPDAQDVTDSAVQTFILNESTPLDNSFVNETGIEVNYAYIKGKIKDGSTWKQTFLIDAATGAINIGLLDAEGKAPISFDPVKKIVNVDGSVITKTINAANFVMTNLTGQDNPAIYTQGKTWGDTKSGIWMGMDNVTAKPKLDIGNATQYIRYDGNILRISSEVVIGTPNGDIDIQTGIQGKQTVFIYIIGTSLPAKPTSPAYPPSGWSKTPPNRTSNTQNIYCSTGTLDPVTNQLVSGTSWSDVVQWSGTEGVDGRPGATGQRGPGMYSLAIANLTAWNDSQANSFFTSNFGSGPVKYDVLTEYKSGAPGTAFTRQWNGSAWTSPAMVLHGDMIVNGTVTASKIVANNAFLSQIGVNIIYDRAAALSSNPEGSYKMKIDLQNGYIHIR
Protein: DJ-1 protein homolog E (AtDJ-1E) (Protein YELLOW-LEAF-SPECIFIC GENE 5) (Q9ZV19)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in oxidative stress response.
Interaction partners:
- Hydroxyacylglutathione hydrolase 2, mitochondrial
- Hydroxyacylglutathione hydrolase cytoplasmic
- Probable hydroxyacylglutathione hydrolase 2, chloroplastic
- Hydroxyacylglutathione hydrolase 1, mitochondrial
- Probable lactoylglutathione lyase, chloroplastic
- Lactoylglutathione lyase
- Lactoylglutathione lyase GLX1
- Protein DJ-1 homolog C
- Protein DJ-1 homolog D
- DJ-1 protein homolog F
Sequence:
MASAVQKSALLLCGDYMEAYETIVPLYVLQSFGVSVHCVSPNRNAGDRCVMSAHDFLGLELYTELVVDQLTLNANFDDVTPENYDVIIIPGGRFTELLSADEKCVDLVARFAESKKLIFTSCHSQVMLMAAGILAGGVKCTAFESIKPLIELSGGEWWQQPGIQSMFEITDCVKDGNFMSTVGWPTLGHGIKLLLESLGGKVCSLEKKQASVLFLIGDYVEDYGINVPFRALQALGCKVDAVTPNKKKGEVCATAVYDLEDGRQIPAEKRGHNFFVTASWDDICVDDYDCVVVPGGRSPELLVMNEKAVALVKSFAEKDKVFAAIGQGKLLLAATGVLKGKRCASGKGMKVMVKVAGGEAVMEKGCVTDGKVVTAASATDLPAFLFDLSTALGLTVMF
Protein: Ring-exported protein 2 (Q8I2G0)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKMYLAEIFSSGKESLLSLKDTLGSSNFSPLKPCEGLECLPQVLFLYVIFLLLCTGIFMHNKNKLKKQQRLTNMNDSYDAKNSGFAEQYDQQQH
Protein: Calcium uniporter protein, mitochondrial (MaMCU) (E9DVV4)
Organism: Metarhizium acridum (strain CQMa 102)
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:29995856}; Multi-pass membrane protein {ECO:0000269|PubMed:29995856}.
Interaction partners:
- Prohibitin
Sequence:
MGHVLGGTLLAANRLARPPAVVLGKPRVCCWRASPWPVIVSSALQFSSSSARHTNYTSARYEARGRSTTQRKVDDRPWHRESSGSLPKSTSPDPTGGDATKGRLLTTPTRLLKLILPIPFHPEQEYINSDETKTNKPKEDAVEPLALLVHPQQPLSYLERLIQAEIPPLLVKDREKLPEIIFRAEADYTGGNKSNDGRREESNGNGSNVASYSGLGREGPSKGDTHWVRWSGSTEIGDFIRDAARGREFSVTIEGHAEELRVAVPSFKDRTYYMRMRLRRMSQEIDQMATVKRECDLLAHKGAHALAKGGFAALAAWWGIVYYVTFHTDMGWDLVEPITYLAGLASIMGGYLWFLFISRDLSYKAAMNVTVSRRQNALYQERGFDPAKWDQLVHDANGLRREIKFAATEYGVEWDEMKDLGGEEVKEVLEEEKGGKARKREQEDEDGDGDDDHDHDHDHVSHGAELQGQDILHANEAAANVPGD
Protein: Solute carrier family 2, facilitated glucose transporter member 7 (Glucose transporter type 7) (GLUT-7) (hGLUT7) (Q6PXP3)
Organism: Homo sapiens (Human)
Function: Probable sugar transporter. Even if its physiological substrate is subject to discussion, it is able to transport glucose and fructose. Does not transport galactose, 2-deoxy-d-glucose and xylose.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16186102, ECO:0000269|PubMed:28083649}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:29548810}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETIDAGPPTASPAKETSF
Protein: Beta-glucuronosyltransferase GlcAT14B (EC 2.4.1.-) (GT14 family glucuronic acid transferase 2) (AtGlcAT14B) (Q9LFQ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Beta-glucuronosyltransferase involved in the biosynthesis of type II arabinogalactan (AG). Modifies both the beta-1,6-linked galactan and beta-1,3-linked galactan present in type II AG.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9FLD7}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Probable xyloglucan galactosyltransferase GT14
- Beta-arabinofuranosyltransferase RAY1
- Beta-1,6-galactosyltransferase GALT29A
- Beta-1,6-galactosyltransferase GALT31A
- Fucosyltransferase 6
- Hydroxyproline O-galactosyltransferase GALT5
- Probable fucosyltransferase 4
- Hydroxyproline O-galactosyltransferase GALT2
- Beta-1,3-galactosyltransferase 7
- Hydroxyproline O-galactosyltransferase GALT3
Sequence:
MKKLKSYYMQVRNQQQSLDRKWILPLAIGSICSLFLLLLTNLASSSGQTRLIPFSVYGFRSSVFVESKINPVSVSLTVSVSPPPPPRLAYLISGSSGDGQMLKRTLMALYHPNNQYVVHLDRESSPEERLDLSGFVANHTLFQRFQNVRMIVKANFVTYRGPTMVANTLHAAAILLREGGDWDWFINLSASDYPLVTQDDLLHTFSYLPRDLNFIDHTSNIGWKESHRAKPIIIDPGLYMSKKADVFWVSQKRSMPTAFKLFTGSAWMMLSRPFVDYFIWGWDNLPRIVLMYYANFLSSPEGYFHTVICNAREFTNTTVNSDLHFISWDNPPKQHPHHLTLDDFQRMVDSNAPFARKFRRDEPVLDKIDSELLFRSHGMVTPGGWCIGTRENGSDPCAVIGDTSVIKPGLGAKRIEKLITYLLSTENFRPRQCR
Protein: Rotatin (Q8R4Y8)
Organism: Mus musculus (Mouse)
Function: Involved in the genetic cascade that governs left-right specification. Required for correct asymmetric expression of NODAL, LEFTY and PITX2 (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Colocalizes with the basal bodies at the primary cilium. {ECO:0000250}.
Interaction partners:
- Protein phosphatase 1 regulatory subunit 35
- SCL-interrupting locus protein homolog
- Pericentrin
- Centrosomal protein of 85 kDa
- Centrosomal protein POC5
Sequence:
MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERLLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYSPAVQHLIDLGAVEFLSKLRPNVEPVIQAEIDGILDGLFILPSEVPALCSSSYHTDQIELSQQPEVLTGYFPQDKSNFQQMEVPPGPAGNQAVKWLRFSVFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQGLLCLVKLAFGGDGKHRLALQSVSCLQQLCTSLRNRLNFYRDPNFFSSRQDTVSQNSSLSYCHEARGPYHSPNPSPGSSSSRPSVVGRTGQRPRGDGQDWDAVSSSGSSSHTHVNSRISVHSPLDVAPVDLPELEAEDTLELQFQQLSLPQFCISTLEAAAPLLRTGSREMIIRVLELLAEDMLLIGQAISSEIWDDNSLFAINVKEKLLQVLGSLGETMCYRKTSFSMEQAEAVLVHHRMAFVSISLFTVRLLQLLLPVEKASEFLPESMSAALFFVSLDMPISLEYPEIHDTVVAYLEQLDSENYSIYKRTAEAVYSIECTCNFLSDVGKEGEKNLLELVELADQALRSFSYHQHSPLIKEIICICSKIWKSAQASPLLQGESQKVFLHMLSHPLPQVKVETYQCCLEIVKECLGVQNVTKPVSSLCSGIHFLLHPKVLYEISAFGIQESKNEVNAAAKAILLYLLQGRLMMTALTWNKFIESLAPVIPVLQGYADTEDPLGNCILLLSKVSSEAGEGALPCTARLKSVLRLLLVKKPSVRSLALKLLAFHLTSEEGADKKRPFIDAGVLSRVTNLFIVKKPIDLKLDDRRELVIKLETVKKVCDIFTSDDVDLVLRKSAAEQLAVIMQDIKMHTVVKKLCLVEKIIGHLNEFVGQDGEVIECLIQPCLTLLRKVLYADPVIRVSLSQQASLLTLLLRVSLIFHEDCTVVAEVGALFCLLLFDEVSRMDTWSDTLSDKPSLSSVFSLPVSVFRRYHLPVHVTGHHAVSPYSIVLPLPTECLTLKPVSDMLRIAWNLAWYHGSDNLLKQMTSEAKIQEFLDTLQLSTEDILALKITYTDSGLKDCLQSIIQAGGHRDVRAAITRMSFYLLNDKLSLKDDIGPCGVTLKSLAWHTVLNRFLQVLPACTEDEKLLIDIIHFLNKLIKEQRKNPSIELLNWILELLLRHNPSPLLDLLVLTDSHAGEETDDVRTAVRQQLQKELISLLNSLLLVFMTVSDRKCLELFYVFQTQLSLKLLQCLRVTDAPHFYGLPSLERTLAGMAHLTAFPGWSAHSPLSKPLEICGKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTGLCLLHLSHEMIVQAPGSEWMPLWFLPLGSHSEEHAPTQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTIEAGCVALANSCQNISGGLWGTVVNILLDQSECSLVRREAAFILQNLLVIPMPSEIIKDYTWQGPCVHDEDSGLSLSGKPALQALLYHCRFYEHLTHMVKHCYVGRYIFDFNFSAFTETSEYSDLNGLDDSFKFWRAPSGTSTQDHEPSSLSTSETMVAASVVSSEIQPLLPSTLLPETALDQFVTQGQREMRPVRPRDSLLSTSLNRQYVFVTPSLLSAVCSLLDNLLAVTPRDAANAFQQAHLIELLCSTVDASLIEMCIQELKTPLPLPSAVEHIQAQASFFLEYLSSLSQLLKSCLLVEPKLVTQDELLKPLITNVIRVLIVCPKDVLDVQLVLAFYRTWTHLFDLLATLLRKAGAVSLVPLTSALAKHWEAVTDTLCRCVGLSFKCPALTIASLQFLSVLLAEEEKRRVQDKDKTNEGQAPTVALLLDGTQGSLSSSERLNETILQCYEGISPKDVLKRVAANALLSLLAVSRRAQRHALRSDLIENCMEQMKHINAQLNLDLLRPGKAVLKKKEDGFIKELSITMQLLRNCLYQNEECKVAALEARLVPVLHSLWPWLLMEDSLMQIALQLLCVYTANFPAGCSSLCWSNYGQCIQTAHRGTPSSSLILCILKLASQMPAENTTIQQLVFMFLSNLALSHDCKGVIQKSNFLQHFLSLTLPKGGNQHLSTVAILWLKLLLNMSFGEDGQQMILRLDGCLDLLIEMSKYKHKSSPHMPLLIFHNICFSPANKPKILANEKVVTLLAACLESENQTAQRIGAASLWALTYNYQKAKATLKNPSIKRKVDEAYSIAKRTLSNSEENPLNSYYLKCLENLVQLLNYS
Protein: Pleckstrin homology domain protein opy1 (Q96WV2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cell tip {ECO:0000269|PubMed:16823372}. Cell membrane {ECO:0000269|PubMed:33172987, ECO:0000269|PubMed:39239853}; Peripheral membrane protein {ECO:0000269|PubMed:33172987}. Note=Also localizes to the cell division site. {ECO:0000269|PubMed:33172987, ECO:0000269|PubMed:39239853}.
Interaction partners:
- Putative cargo-transport protein ypp1
- Protein efr3
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
Sequence:
MDPGVSSHLRTASLDEARRLPELERVLKSGWLIKKGHATSTKKQLWAVLRRDQLSFYKDEKEYKTKFIFPTQDISAVAYYKEKSPKTFFLYLNEKIIRLIATSNEDAEEWVHVLRSTTGYRAPFSRHPISYILANSSSRTESEPNVQISDTDFDNISTEPRNQTTSPLDLETGQGDHFCTSLYDLIQFGKLRPPGINEENANYPFNPQEVNTLNKHRHSASLQNLYKLLDENKVLMQGTIHWLHGNLHRWSKCWAVVRGYGMTIYNTNREYKPVKVIPIADIQDVAEINVPESSHKYFFTVITQNKPIEFRVDNEDSLILWVAALKTSIDKANGTFTAC
Protein: Glutathione S-transferase omega (GSTO) (EC 1.20.4.2) (EC 1.8.5.1) (EC 2.5.1.18) (Glutathione-dependent dehydroascorbate reductase) (Monomethylarsonic acid reductase) (C1BFM5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH-ubiquinone oxidoreductase chain 4L
- NADH dehydrogenase iron-sulfur protein 4
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- Uncharacterized protein
- Glutathione synthetase
Sequence:
MASEKCFAKGSSAPGLVAKGQIRLYSMRFCPFAHRTRLVLHAKGIKHDTVNINLKDKPEWFLKKNPLGLVPTLETSSGQVIYESPITCDYLDEVYTDKKLLPADPFQKAQQKMMLENFSKVTPYFYKIPMGKKNGEDISVLEGELKEKFVKLNEDLVNKKSKFFGGNAITMIDYMMWPWFERLEIFELKHCLDGTPELKKWTEHMSEDQTVKATMFPTETYKAFYKTYADGKPNYDYGL
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog) (Q9VTC2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis.
Interaction partners:
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- Dysbindin protein homolog
- Biogenesis of lysosome-related organelles complex 1 subunit 5
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- SNAPIN protein homolog
- Hermansky-Pudlak syndrome 4, isoform A
- BLOC-2 complex member HPS5 homolog
- GH27401p
- Uncharacterized protein, isoform A
Sequence:
MQSNIENVSRDYAKILQSADLEKEINPLCTNIEDMLARLDEFETLLASVRAESNGMMANNVCSILGFTDSFEQLKARIDGLEQCVGVVSANLSEVERSVDIAEEELHVTDYSLKGLLLKPLKAKLSASDTSTLSSLPRSNLVEEEYQPVEIYKSDDYFGKSEEENYVAK
Protein: Pulcherriminic acid synthase (EC 1.14.15.13) (CYP134A1) (Cyclo-L-leucyl-L-leucyl dipeptide oxidase) (Cytochrome P450 CypX) (O34926)
Organism: Bacillus subtilis (strain 168)
Function: Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. Catalyzes the oxidation of cyclo(L-Leu-L-Leu) (cLL) to yield pulcherriminic acid which forms pulcherrimin via a nonenzymic reaction with Fe(3+). Substrates with small alkyl groups (cAA, cLG, cLP) exhibit weaker binding to CYP134A1, but substrates with larger hydrophobic side chains bind in a similar regime to cLL.
Interaction partners:
- Cyclo
- Polyketide synthase PksJ
- Dimodular nonribosomal peptide synthase
- Surfactin synthase subunit 3
- Polyketide synthase PksN
- Uncharacterized MFS-type transporter YvmA
- HTH-type transcriptional regulator PchR
- Uncharacterized HTH-type transcriptional regulator YvnA
- Plipastatin synthase subunit E
- Surfactin synthase subunit 2
Sequence:
MSQSIKLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFISRYHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKEHSAKRRIVVRSFIGDALDHLSPLIKQNAENLLAPYLERGKSDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSGVADFITSISQSPEARAHSLWCSEQLSQYLMPVIKERRVNPGSDLISILCTSEYEGMALSDKDILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRYKPPVQLIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQPDVFNIHREDLGIKSAFSGAARHLAFGSGIHNCVGAAFAKNEIEIVANIVLDKMRNIRLEEDFCYAESGLYTRGPVSLLVAFDGA
Protein: Nicotinic acetylcholine receptor subunit Dalpha6 (Q86MN8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MDSPLPASLSLFVLLIFLAIIKESCQGPHEKRLLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTSVVVKHGGSCLYVPPGIFKSTCKMDITWFPFDDQHCEMKFGSWTYDGNQLDLVLSSEDGGDLSDFITNGEWYLLAMPGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKLTLGVTILLSLTVFLNLVAESMPTTSDAVPLIGTYFNCIMFMVASSVVLTVVVLNYHHRTADIHEMPPWIKSVFLQWLPWILRMGRPGRKITRKTILLSNRMKELELKERSSKSLLANVLDIDDDFRHTISGSQTAIGSSASFGRPTTVEEHHTAIGCNHKDLHLILKELQFITARMRKADDEAELIGDWKFAAMVVDRFCLIVFTLFTIIATVTVLLSAPHIIVQ
Protein: Lipoprotein, putative (O51573)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Interaction partners:
Sequence:
MRKCFVSLSLLLIFFACSSNVEIELNDDISGIVSIFVNVNREFEKIRKELLTTLVGEEIANMPLFPVDEIKKYFKNGEEKLGLKLLSIKTQGDSINLVVKFDNLIKILGDYMKKPDISVFKIEKKDGKNIIELNINLENATKNINENKEYISDALAALLPSDEIPMSAKEYKDVLVYFLSDFTSKASELIDNSKLNLVVKTSRNVQEQFGFKQINSNTLRFEMDMVKGLSLETPIKLRLVY
Protein: Oligodendrocyte transcription factor 2 (Oligo2) (Class B basic helix-loop-helix protein 1) (bHLHb1) (Class E basic helix-loop-helix protein 19) (bHLHe19) (Protein kinase C-binding protein 2) (Protein kinase C-binding protein RACK17) (Q13516)
Organism: Homo sapiens (Human)
Function: Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. Cytoplasm {ECO:0000250}. Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. {ECO:0000250}.
Interaction partners:
- DNA-binding protein inhibitor ID-4
- Glial fibrillary acidic protein
- Oligodendrocyte transcription factor 1
- Chondroitin sulfate proteoglycan 4
- DNA-binding protein inhibitor ID-2
- Transcription factor SOX-10
- Homeobox protein Nkx-2.2
- Paired box protein Pax-6
- Myelin basic protein
- Nestin
Sequence:
MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK
Protein: Uncharacterized protein C794.15 (Q9USI0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MSTSRLLLPTTNQQQNSSPVIKEVDLNQNTPIPVVWQKTKKPPFVSFPRHEPSETIVISSKPRLFSFAKKIKPEAEQRKRKRTTEI
Protein: Uncharacterized protein YKR011C (Q02209)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
Sequence:
MSKLETVYLYAGEEQPRVKLTCIKEGLTLTQVIKFVHSIQELYGIELQTSETITENLKIDCAPAYLKPNCIPHFYILEYEEISDTFFIWKSDGRWQLNKLSALLYVDNDANVVKNTSWKEVFQNDQRFKNYDKRAWLQNCLEKMNRDLSKLNVEQFWSQYDKICQSIAKQKKKQEQFNMEVFDNFKNIVSIAIIKTKVLSNKRLLTTTLKNYHNSMKKKYNIQEQNLKENSLASCSNNEPSASLESESRHFSPVNSLSPSSLSTDDEAVSTDYIYKGPESKPNVNFMHSSATNDLIKSNFESYFKLMAEDYETFDLRAWSRQRPRKFQLVEKKKITKNPPNSHHPHKNGKISF
Protein: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha) (P50213)
Organism: Homo sapiens (Human)
Function: Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Subcellular location: Mitochondrion.
Interaction partners:
- Isocitrate dehydrogenase subunit gamma, mitochondrial
- Isocitrate dehydrogenase subunit beta, mitochondrial
- Aconitate hydratase, mitochondrial
- Isocitrate dehydrogenase, mitochondrial
- 2-oxoglutarate dehydrogenase complex component E1
- 2-oxoglutarate dehydrogenase-like, mitochondrial
- Isocitrate dehydrogenase cytoplasmic
- Cytoplasmic aconitate hydratase
- Succinate--CoA ligase subunit beta, mitochondrial
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
Sequence:
MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD