Protein: Polyketide synthase RzxC (Q4KCD7)
Organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- AMP-binding enzyme
- Non-ribosomal peptide synthetase OfaA
- Non-ribosomal peptide synthetase OfaC
- Non-ribosomal peptide synthetase PvdJ
- Non-ribosomal peptide synthetase OfaB
- Non-ribosomal peptide synthetase PvdD
- L-cysteine--[L-cysteinyl-carrier protein] ligase
- Non-ribosomal peptide synthetase PvdL
- [acyl-carrier-protein] S-malonyltransferase
- Cytochrome P450 monooxygenase
Sequence:
MQPLATRHGHVTPAYLQRWLAESLKYVAGVETGDAGALWQQWDEGLSGWRQDPDLAPRALLLDACLKGLPGLLRGEQSAPGLLFPNGSMSLVEGVYKHNRVADYFNQVLIEAVLAYIESRPADAEPLRILEIGAGTGGTSAGLLAALAPWRSQMGEYCYTDLSRAFLQHGSDQFAAQHPFLHTRLFDVSRPCAEQGIDTDHYHLVVATNVLHATPDIRQTLRNAKALLCKGGLLMLNEISEASLFTHLSFGLLEGWWLYRDGPLRLPGCPGLSPAGWQAVLEQEGFSPVLFPARQAHAQGQQIILAESDGIVRQPVVGHQRPVPAAADSRAPRETYSPGPDQSSADAWRRRVADFLRHLVSATLKIPADKMSLSRPLEDYGLDSILVVRLTHAFSEHFAAVDSALFFEVPTLAALTEHFIQQRGEELQRLLGQPEAEQPAPPAPASTPHSSAKAREQGAGGPIAIIGLDGRYPGAQSMSDLWRNLAGGHCAIGEIPEERWDWQRYFSAEKGQPGHLYTRWGGFIEGIDQFDAAFFRISRTEAERMDPQERLFLQVAYHSIEDAGYNPATLHQQGEVGVFVGVMNGSYNPISNYWSIANRVSYQLDLQGPSLALDSACSSSLTAIHLAVESLISGSCDLAIAGGINLIVNPQHYLGLCEMMMLSRGEQCRAFADDADGFVDAEGVGAVLLKPLERALADGDRIYAVIRGGAINAGGKTNGYTVPSAGAQQRVLEKALARAGVNARQISYIEAHGTGTALGDPIEISGLSRVFAGSDGAPCAIGSIKSNIGHCESAAGIAGLSKVLLQLQHCQLVPSLHAAQPNPKIDFAHSPFRLQQQLAPWSTQGEPRIAAISSFGAGGANASLIVEEHLASPDSRPAMPGPWLILLSARDRQRLTQAVTRLQDFLATQDAQQVALADLAWTLQVGREAMAERLALQVDSLAELQRRLAQWLAGETQEQVLQGHSDPYDETLEEPGTQLIEQWLQHQQLRELAAAWVAGAVVDWPKLYRHDAYRRPLRISLPGYPFARNSYWMPGLAHPPAHEVRSAEPSDQDLSGCCYLPRWQAQSADEQAQAPGNGAVLLVTLGESAAASEGLLAALTEHYQDRRQVLRIDCTLGTTAQLAADHWRCSAADPTGWATILAALGPVAQLLVISGQSADELSPAALADSLQHHELPLLRLFKALPSQVPEGHGIDCFLLSFGRYAFAGAPQRGNPLGAGMAGLGYALAQSEHRVHLRNLDLNRDELETPDSRQRLLAQILAEPASQRGEPIKLSRGERFVQQLIPLALPANRGSASALQHNGVYLILGGSGVIGQVISRQLIEHYQARVIWLGRKAADSPQLQQSLGHEQWRGRVDYLQVDGTDLVQLQQAVALVNQRYGRINGAVFCAMVFDFENSIQHSSEAQFQHILEIKSRGSLNFYQALAGQALDFLCYFSSGQGFAFSGAAKLSAYACGITFADAFAEAIGPSACFPVGVINWGFWRASLQAQAVSEHLDALDDDQGFTCFSRFVAHLAGSSLRRLLCIKASPAVRQLMAVPEGLQGRLEPGALASARLPGVELRPAEHERLQQLFDPQMLDQSIAVLLLVQLQTLGIFTSPEVQSAELWRQQAGIGERYRRWWQECLAILLEHGYLQQQGQGLGVATPIARSRHAAILTAWKTQCEHYLADPERRAQVTLVDACLMHLPQILTGQIQATDLLFPDGSMDQVEGIYKHNSLSDFFNAQLASRVSAQVQRLVAAEPGRPLRILEIGAGTGGTTAPLLAALEPWAEHLGEYCYSDLSHAFLQHGHASFAAGRPYFTTQILDISQPPGNRQGYDIVVATNVLHATANMRHTLAHVRSLLRSGGLLALNELNRKTCAATVTFGLLDGWWLYEDPGVRIPGSPLIAEQTWLELLWSSGFEQVDLHLPEPLALGQQIITAHGDALTLHSVAPPLPSTAADDKESGLNEHPVSATATAAPVADRLQQVIIQALARTLKADEQSIGLRTPFSDYGVDSILGVGFIKQLGQQLRIKLNSALLFEHATVSKLQHYLQQAHGPQIAQALAAIPSSEPSSEQAGEAPAVQPAAPSNPVLAAALAGNQPASQPGHSGLGAIAVIGMAGQFPGADDVDALWDNLLAGHHSVQALGPDYLQPEAYSADRQPGKSYCNRAGILKDRDCFDPLFFNLTPHEAESMTPHQRLVLQESWKALEDAGYNPMTLAGQAVSLYVGAEPGGYHHDSFTGSSEAIIASRLSYFLDLKGPAMVVNTGCSSSAVAIHQACESLRHGESRMALAGGVYALLDQRGLISLSAIDMLSPSGQCHAFDAAADGTVISEGVAMVVLKRLEDAEAEGDPIYAVIEASGVNQDGVSNGITAPNGDAQEQLLRDTWRRFGVDPGHISYVEAHGTGTRLGDPVEANALIRALRGFTDAQGYCVLGSAKANLGHAAAAAGVIGLIKVLLSIRHRTLPAMPGFERINPLIELEHSPFYINRQAQAWQASGGQRRVAALNSFGHSGTNAHLVIAEYPDLPPPVPSTAADVVSRVIVLSAKTVESLGDNVRALARWLDRSEAPLSHIAFTLQTAREPMAVRAALVVSDLDQLRTQLTRLAKGDTPAMAEGDSGRLARDWLAGGSIDWAALWPAGSARRIHLPGYQFAKERYWAEQTPIPLVQPPAAQRLESPATGLFLARPVWQEPLSTGADASAELGQSLLLWVGFNDVQVAQLQTLSAAAGVSGEVLACANSGPAACYQALAIALLQRLQALKGRAHLELMIAEQTPEDRLYAGLEGLLKSACLEQPALSARCLLVKTEDEQPLAAAQLALLPGLLGARRLRARSVLQRLDLQGQHQELQWQELADDVAVGRTSDRPLWKDRGVYLITGGAGGLGLIFARTIAEQCRDVTLILLGRSHLDSRQQAQLQAIRDLGAAVVYQPLDLTDAQGLERLIAQICTAHGGLNGVLHGAGVNRDRLLAQKTPQDVVEVFAAKVLGTDLLDRACRRLYLDFFVLFSSCSAVLGSVGQADYAAANAFIDQFAELRNLRVEQGLRFGHTLSLNFPLWRDGGMQISAADQAHIRQQTGMAPMQSVHGIQALQLGLSAGLARLLVIEGDLAQIRGQFGAAEPVDAQPAPGLPRVTVDPAQLSAAVLERLKAVFCAVTKLPPARVECDAPLEHYGIDSIMIIRLNRALEERFSAMTQLRPAERLLSKTLFFEYHSLNALSAYLVAEHQRACLIWSGLAEEAPIAAPAVGQASPVPASMAMAAAEPIAIIGISGRYPQAANLDEYWRNLKAGRDSITEIAPQRWPLEGFYVDSVAEALKQARSYSKWGGFIDGFADFDPLFFNISPREAVNMDPQERLFLQSCWQSLEDAGITKADLATKYQGNVGVFAGITKTGYGLYGPALREQGQLVFPRTSFGSTANRVSYVLDLNGPSEPVDTMCSSSLTALHRACESLRRGECRMAFAGGVNLYLHPSNYVELSAGQMLSKDGRCRSFGEGGNGFVPGEGVGSLLLKPLSQALADRDNIHGVIRAVAVNHGGKTNGYTVPNPQAQAKVIRLAIDQAGLDASQISYIEAHGTGTELGDPIEVSGLTQAFALDQVALGHCALGSVKANIGHLEAAAGIAGVSKVILQLKHRQLVPSLHAATLNPNLRLDATPFYLQQTLDDWQPANAGPRIAGVSSFGAGGANAHVLLQEHDEYRPMPHASDAEVILLSARDADRLRDYAQALLAYIEARPGLSGADLANLAYTLQHGREMMAARLGLIVDGVATLATRLRRFIDHDTTADADFHRGDLQGKRPAAQADAEQAMQVSQWVESGQLHQLLQSWVKGAVIDWSLLQARRSGALPYRISAPVYPFARERYWLPAVQPGAGAVTQTPAAPAPAAAASDGLSYLARWQAVGQGAEASSVEPVPVQQRCVLIVAEAALRPVAEAITANYLLSAGFATGAGRVIRLEPGRQTACLAADHWALDATDPQALEQCLGAVPAIDCLYFFAGHAAAADWQAQLDSPQNHEILLLRLIKWLKQHSPCQAIDSYIISQDNFDISGEAVSAMGGGLTGMAYAIAQGEHRFRVRNLDVASRELADSRRRPSLLRQLQSEAGLARGEVLALRDGVAYRQRLFTLSWQAQPSAVDGGFVTPALKQGGVYVILGGSGTVGSIISRYLLADYQARVIWLGRSSADDPKVQQRLASCVQRVQGSVQPSQLHYLQADANDPASLQRAVAWIKQHHGAINGAIFSAVVFNHEDPITRIPEAQFDAILQVKSRGGIEFYRALADEPLDFMCYFSSGQSFAFSGAARLGAYAAGITFGDTLVRSLRQQAAFPVGVINWGFWLSSLTEQQAADPTAQPMSRHAGALQDREGFECFARFIDALSQGQLDQLLCMAASAPVQQLMQLQPEPIVLGQSAGHAADDGCERYRQAAAPLLAAHDPAPFDRAMAAMTLVQLCRMGLFSQPGQFADSDGLRRQAGIGEQYARWWATSLEMLQQQGLLERRGTQVALTAPVDLLALEQHWCRLRDQLLAEPQRKAQVELVDACLQQLPAILGARTQATDVMFPQGSMHKVEGVYRHNALSDYFNQVVAGVVQQHLEGLSIREPQRQIRILEIGAGTGGTSSIVLPVLQPWRERMAEYCYSDISQAFLMYARNTYGAANPFLTYQLWNVEQPPQAQGLELGGYDIVIAANVLHATGSIRRTLAHAAALLRRDGIVLLNEISDRSLFAHLTFGLLKGWWLYEDPELRIPGTPALYPQSWARVLGESGFHSVAFPAQCAHGLGQQIVVAQRNGVAPAALFVPDEKPQPLPLATRPLAATVASEPLPSAPAANGGGRGALTALALDGLAKTLQLEPGRIQVDQPFADYGIDSILGVSFVSHIGAALGIELNTALLFDYPSLESLVDYLLAQYPAQCAALGGDAAPAAATEPAPSVGQLEAAFLCGELAIDELLQLVNHSTSAHHDAAQATAGKGQS