wanglab/gogpt-training-data huggingface dataset:
Protein: Plastid division protein PDV2 (Protein PLASTID DIVISION2) (Q9XII1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the plastid division machinery consisting in a binary fission accomplished by the simultaneous constriction of the FtsZ ring on the stromal side of the inner envelope membrane, and the ARC5/DRP5B ring on the cytosolic side of the outer envelope membrane. Positive factor of chloroplast division required, with a dosage effect, to mediate the recruitment and dimerization of ARC5/DRP5B at the midplastid constriction site in the cytoplasm at plastid outer envelope membranes (OEMs). Prevents ARC5/DRP5B GTPase acrivity. Relays plastid division site position between stroma and outer surface via interactions with the cytoplasmic ARC5/DRP5B and the inner membrane ARC6 that recruits stromal FtsZ ring. Binding to phosphatidylinositol 4-phosphate (PI4P) modulates negatively chloroplast division.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000269|PubMed:18812496, ECO:0000269|PubMed:19453460, ECO:0000269|PubMed:32005784}; Single-pass membrane protein {ECO:0000269|PubMed:18812496, ECO:0000269|PubMed:19453460}. Note=Plastid equatorial positioning in a discontinuous ring mediated by ARC6 (PubMed:18812496). Colocalizes with ARC5/DRP5B at the chloroplast division site (PubMed:32005784). {ECO:0000269|PubMed:18812496, ECO:0000269|PubMed:32005784}.
Interaction partners:
- Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic
- Dynamin-like protein ARC5
- Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3
- Cell division protein FtsZ homolog 1, chloroplastic
- Plastid division protein CDP1, chloroplastic
- Protein MULTIPLE CHLOROPLAST DIVISION SITE 1
- Dynamin-related protein 3B
- Dynamin
- Chromophore lyase CRL, chloroplastic
- Cell division protein FtsZ homolog 2-1, chloroplastic
Sequence:
MEDEEGIGLILARATELRLKISDCIDNSSTTVSDNGDGNEDLSPGEGRKSEIIGNQDKDFDSISSEDVDEAEAERLLRIRDALEALESQLASLQNLRQRQQYEKQLALSEIDYSRKMLLEKLKEYKGKDFEVLRETTTFAGERVDYENDLLLPPYPVHPPLSLGLDNNNGYLSHLPSKKKSDANGFGSGHVRNEAEAKSPNGGSGGSSHGVIRFLGSVAKIVLPIIGVISLLSASGYGPEMRKRGASLNLFGLLPHRATRGKRTPNQCPPGKVLVIEDGEARCLVKERVEIPFDSVVAKRDVTYGYG
Protein: Proteasome subunit alpha type-1 (Proteasome subunit C2) (Q27562)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Proteasome subunit beta type-5
- Proteasome subunit beta type-3
- Proteasome subunit alpha type-7
- Proteasome subunit alpha type-2
- Proteasome subunit beta type-7
- Proteasome subunit beta type-1
- Proteasome subunit alpha type-3
- Proteasome subunit beta type-6
- Proteasome subunit beta type-2
- Proteasome subunit alpha type-4
Sequence:
MYRNQYDSDITTFSPSGRIHQIEYAMEAVKQGGAAVALKSKQFAVLVSLKRSSSELGSYQKKIFVVDDHVGIAISGLTADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHTQRYGRRPYGVGLLVAGYDQLGAHIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEECTLEQLITHGLRALRETIPNTDDTLNSKNVSIGIVGEGQPFKIIEEADAQPYLNLLENEEPVEMQTN
Protein: Cell division protein FtsP (P26648)
Organism: Escherichia coli (strain K12)
Function: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
Subcellular location: Periplasm {ECO:0000255|HAMAP-Rule:MF_00915, ECO:0000269|PubMed:10593889, ECO:0000269|PubMed:19135451}. Note=Localizes to the division septum. Localization requires FtsZ, FtsQ, FtsL and FtsN.
Interaction partners:
- Sec-independent protein translocase protein TatC
- Sec-independent protein translocase protein TatB
- Sec-independent protein translocase protein TatA
- Trimethylamine-N-oxide reductase 1
- N-acetylmuramoyl-L-alanine amidase AmiC
- Cell division protein FtsN
Sequence:
MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRRGQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMTVAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGMWLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQSPYVEVSRGWVRLRLLNASNSRRYQLQMNDGRPLHVISGDQGFLPAPVSVKQLSLAPGERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTDSLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADEPQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNSQTLEMADRGSIGQLLVNPVP
Protein: Protein NLP5 (AtNLP5) (NIN-like protein 5) (Nodule inception protein-like protein 5) (Q9SFW8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00852}.
Interaction partners:
- MOB kinase activator-like 1B
- Putative MOB kinase activator-like 2B
- MOB kinase activator-like 2A
- Rop guanine nucleotide exchange factor 14
Sequence:
MENNSLPMDPAMDSSFMDGLLLEGCWLETTDASEFLNFSPSTSVAPFDPSSFMWSPTQDTSNSLSQMYGQDCPERSSLEDQNQGRDLSTFNRRWWIGPSGHHGFSVMERLVQAVTHIKDFTSERGSLIQLWVPVDRGGKRVLTTKEQPFSHDPMCQRLAHYREISENYQFSTEQEDSDSSSRDLVGLPGRVFLGKVPEWTPDVRFFKNEEYPRVQHAQDCDVRGTLAIPVFEQGSQICLGVIEVVMTTQMVKLSPDLESICRALQAVDLRSTEIPIPPSLKGPDFSYQAALPEIRNLLRCACETHKLPLAQTWVSCLKQSKTGCRHNDENYIHCVSTIDDACYVGDPTVREFHEACSEHHLLKGQGVVGEAFLTNGPCFSSDVSSYKKSEYPLSHHATMFGLHGTVAIRLRCIHTGSVDFVLEFFLPKNCRDIEEQRKMLNALSTIMAHVPRSLRTVTQKELEEEGDSMVSEVIEKGVTLPKIENTTEVHQSISTPQNVGLVFDGGTTEMGELGSEYGKGVSVNENNTFSSASGFNRVTEKKRTKAEKNITLDVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGIQRWPSRKIKKVGHSLQKIQRVIDSVEGVSGHHLPIGSFYASFPNLAASPEASSLQQQSKITTFLSYSHSPPAKSPGSSCSHSSSCSSETQVIKEDPTDKTRLVSRSFKETQTTHLSPSSQEDDFLRVKVSYEEEKIRFKMRNSHRLKDLLWEIAKRFSIEDVSRYDLKYLDEDNEWVLLRCDDDVEECVDVCRSFPGQTIKLLLQLSSSYLPERSSVSGCLS
Protein: Inner membrane protein YqjE (P64585)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Uncharacterized protein YqjD
- Uncharacterized protein YqjK
- Protein YqjC
- Uncharacterized protein YgaM
- Uncharacterized protein YccJ
Sequence:
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
Protein: Genetic suppressor element 1 (Q14687)
Organism: Homo sapiens (Human)
Interaction partners:
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
- Histone deacetylase 1
- High mobility group protein 20A
- Lysine-specific histone demethylase 1A FAD-dependent demethylase 1A)
- REST corepressor 1
- REST corepressor 3
- Histone deacetylase 2
- Zinc finger protein SNAI1
- Zinc finger MYM-type protein 2
- Zinc finger MYM-type protein 3
Sequence:
MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCLALPAMHWPRGYLKGYPR
Protein: Zinc finger chaperone ZPR1 (P53303)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9852145}. Nucleus {ECO:0000269|PubMed:9852145}. Note=Translocates to the nucleus after nutrient stimulation. {ECO:0000269|PubMed:9852145}.
Interaction partners:
- Uracil phosphoribosyltransferase
- Transcription corepressor MIG3
- Regulatory protein MIG2
- Uncharacterized GTP-binding protein YGR210C
- Elongation factor 1-alpha
Sequence:
MSEQKEDLFKPVGEAAAEVEDESIAEQNKANDGVKLTGAQDAMGHPVQEIESLCMNCGKNGTTRLLLTSIPYFREIIIMSFDCPHCGFKNCEIQPASQIQEKGSRYVLKVECREDFNRQVIKSETATCKFVELDIEIPAKRGQLTTVEGLLSEMIDDLSQDQEMRKSIDEALYKKIDDFIQKVKSYINCEPNTIPITFILDDPAGNSWIEYKPGEPQHKWSHTQYVRTDEQNVQVGIITRDQLEQRRQEQLKQLANRERNPSESVKVGSANPQFLSDATDIENFNNEVQTFRASCPSCTQECETHMKPVNIPHFKEVIIMSTVCDHCGYKSNEVKTGGAIPDKGRRITLYCDDAADLSRDILKSETCSMVIPELHLDIQEGTLGGRFTTLEGLLRQVYEELESRIFTQTSDSMDEATKARWVEFFAKLKEAIAGKVKFTVIMEDPLAGSYIQNVYAPDPDPNMTIEDYERTKEQNEDLGLSDIKVE
Protein: Stomatin-like protein stl-1 (H2FLJ1)
Organism: Caenorhabditis elegans
Subcellular location: Mitochondrion {ECO:0000269|PubMed:24385935}.
Interaction partners:
- Mitochondrial prohibitin complex protein 1
- Mitochondrial prohibitin complex protein 2
- alpha-1,2-Mannosidase
- Solute carrier family 35 member F5
- Mitochondrial coenzyme A transporter SLC25A42
- Nose resistant-to-fluoxetine protein N-terminal domain-containing protein
Sequence:
MALTNRLLMNSSALLRSSTLPLAVTSSRQAHAAHNTVINFVPQQEAWVVERMGKFYKILEPGLNFLLPIIDKIKFVQNLREIAIEIPEQGAITIDNVQLRLDGVLYLRVFDPYKASYGVDDPEFAVTQLAQTTMRSEVGKINLDTVFKERELLNENIVFAINKASAPWGIQCMRYEIRDMQMPSKIQEAMQMQVEAERKKRAAILESEGIREAAINRAEGDKKSAILASEAVQAERINVAKGEAEAVILKAESRAKAIERIALALEKDGGANAAGLTVAEQYVGAFGNLAKESNTVVLPANLSDPGSMVSQALAVYDSLSNKKK
Protein: GH19061p (Q961K5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
Sequence:
MLNLLGYNKDDIDSKFNKFIKETDGNSHSDVDTLTTRISTLTHTQDNKFDGNAIDSQNHNDFATPPRPQFKVPSGDHSDSLIAEAILTGNVDAAVELCLEAQRIPEALIIASTAGIETLNRTQTRYLLQQKNELSHVISALVSRDWLDFVNRCTVDSWKEALVAALKHSERKVVDICERLGDRLLSECASSAEFTRNAMLCYICAGSIDKLVTAWYQLKRLEQQNPGYKPNTTELQDLAEMVMLMCKSLEQQGISVDLAGRFAGFLTEYGGLLASQGALTAALQYITTLGGGAAASESDVLQSLRDRINNAVNLDYTQPQAAVAAAPHGYQPTRGRGSFSQPQPSAPMPYGQPPNQYAQPSWPAQVPPLQTSYPGAQQPQAPPQIFNPQPVKPEPLAQPPRPLSNASSSGGPPPAGGASSSGGSGLSGRSKYVLDPSVAAPTSSYGMPYNPVPAPVPSAVPFGGGGVPGPAPQPASVPTYNSNAFNTNPIAAAQPYNPSPLMPAQQNQFVPGVNPIETMPPPAVPPVIQNVQRNPTPPPGWNDPPALKSSRAPKPKPVVEPSAAIFHPLFPVDPNQNQNGYVDPSQYQHAAPLGGVPNTYYNPAAFNNNPQQQQQHQQSYLQPQQPAPGIQQPNWQGQQQTIGYTEQPAPIQQQRQPAPPKEKPPLPEEYIYLQTVLEELKNRCLGATNDPRTKRKFVDVVKRLENLYDCLRDGKLTPTTVQYLNQIVQYIQISDYANAMEIHTQIAFGTDFAQCAGFMQGLKVLLQSASELQLVLR
Protein: Fas apoptotic inhibitory molecule 1 (Q9WUD8)
Organism: Mus musculus (Mouse)
Function: Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19168072}.
Interaction partners:
Sequence:
MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRREWMFKLVGKETFFVGAAKTKATINIDAISGFAYEYTLEIDGKSLKKYMENRSKTTSTWVLRLDGEDLRVVLEKDTMDVWCNGQKMETAGEFVDDGTETHFSVGNHGCYIKAVSSGKRKEGIIHTLIVDNREIPELTQ
Protein: Metaxin-1 homolog (Mitochondrial outer membrane import complex protein 1) (Q9VHB6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).
Subcellular location: Mitochondrion outer membrane {ECO:0000250}.
Interaction partners:
- SAM50-like protein CG7639
- Mitochondrial import receptor subunit TOM40 homolog 2
- AT01806p
- Mitochondrial import receptor subunit TOM7 homolog
- Mitochondrial import receptor subunit TOM40 homolog 1
- Protein clueless
- Mitochondrial import receptor subunit TOM22 homolog
- FI03495p
- IP11229p
- TOMM20-like protein 1
Sequence:
MEMQLGAMLYVYKGEYGLPSIDFECLRALCLLRFTRCPMDVQTSSNPLRSGAGKLPYLQIGNQKFAGYRQIKRVLDLEGYPIDAHLSTKQKHLSTAYANWVFTNLHAYYHYFLFGEPHNFDTTTRGLYAKRTPFPFNFYYPSSYQREACDVVQVMAGFDVNDKLDKHEGDYLVVNAKKVVNLLSRKLGRKVWFFGDTYSEFDAIVYSYLAIIFKIALPNNPLQNHIKGCQNLVNFINRITKDIFRIEGYSSVKLTKTPSGTEASLTASERKFLDSELNTKIVAGVGAVLAMGAFAAWRGIYNQLTTRSSTDYDGIDYEDDEMEEGLD
Protein: Small ribosomal subunit protein uS11B (40S ribosomal protein S14-B) (RP59B) (P39516)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uS11 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22096102}. Nucleus, nucleolus {ECO:0000269|PubMed:15590835}.
Interaction partners:
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein eS19B
- Small ribosomal subunit protein eS6A
- Small ribosomal subunit protein uS2B
- Small ribosomal subunit protein eS28A
- Small ribosomal subunit protein eS21B
- Small ribosomal subunit protein eS17A
- Small ribosomal subunit protein eS26B
- 13 kDa ribonucleoprotein-associated protein
- Large ribosomal subunit protein eL30
Sequence:
MANDLVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL
Protein: Collagen type IV alpha 2 chain (F1M6Q3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
Interaction partners:
- Collagen type IV alpha 1 chain
- CD44 antigen
- Glycoprotein VI
- Integrin alpha-1
- Collagen type IV alpha 5 chain
- Collagen type IV alpha 3 chain
- Serpin H1
- Integrin subunit alpha 5
- Collagen type XVIII alpha 1 chain
- Integrin beta-4
Sequence:
MDRVRFSASGLPLRGWLLLATVTVGLLAQSVLGGVKKSDVPCGGRDCSGGCQCFPEKGARGQPGEVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGTGGFPGLPGPQGPKGQKGEPYALSKEDRDKYRGEPGEPGSVGYQGPPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSDITLIGPTPSTYHPDMYKGEKGSQGEPGIPGITLKGEEGIMGFPGTRGFPGLDGEKGVSGQKGSRGLDGFQGPSGPRGPKGERGELGPPGPPAYSPHPSLAKGARGDPGFQGAHGEPGSRGEPGDPGPVGPPGLSIGDEDSKRGLPGEMGPKGFSGEPGPSAYYPGPPGADGKPGPQGLPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGGRGQKGWKGEAGDCQCGQVIPGLPGLPGPKGFPGVNGEFGKKGDQGDPGLHGIPGFPGFKGAPGIAGAPGPKGVKGDSRTITTKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGTPGTKGFPGEVGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGLPGTPGQADCDTGVKRPIGGGQQVVIQPGCVEGPAGSPGQPGPPGPTGAKGIRGIPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGAPGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGARGDAGLPGQPGLKGFPGEIGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLSGPPGQHGFPGAPGREGPLGLPGSPGLGGLPGDRGEPGEPGEPGPVGMKGVSGDRGDAGVSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRPGFPGIKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPGMKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGLSGIPGLPGRPGFIKGAKGDIGVPGTPGLPGFPGVSGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGVTGIPGLKGLFGEKGAEGDVGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGRPGIPGIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGAPGQKGEQGIPGERGPVGSPGLQGFPGISPPSNISGLPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGEKGWVGDPGPQGQPGVHGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTMGPQGRRGLPGALGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPIGQEGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQNFQSTPSADTLKAGLIRTHISRCQVCMKNL
Protein: Probable dehydrogenase/reductase (O53726)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable fatty acid synthase Fas
- Molybdopterin molybdenumtransferase 2
- Conserved ATPase
Sequence:
MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSFGV
Protein: Nucleoporin NUP82 (Nuclear pore protein NUP82) (G0S4F3)
Organism: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P40368}. Nucleus membrane {ECO:0000250|UniProtKB:P40368}; Peripheral membrane protein {ECO:0000250|UniProtKB:P40368}; Cytoplasmic side {ECO:0000250|UniProtKB:P40368}.
Interaction partners:
- Nucleoporin NUP145
- Nucleoporin NUP159
Sequence:
MPKIKSFAPAWLNEPAPGHKLFAPAADDGTATVPLAYGKKIKPGPRRTIARRGTEIFVACGKQIRWGDLAQLKESWESRPSRSSVGPTSTKKDSSDFDDGAATAGYRIIKTPVADDIRQLVMSPNQDFLAVLTSHTVHICILPDSSHLHIQDTTPFKPKFWTLGPTTHVTSRSAVVSAVWHPLGVNGHALVTVTEDAIVRVWELSTADRWTFDAPTLAIDLKKLADATYLDQDFGVSTSATNKGFSPDAFDMEVAAACFPTRDSGGWAPMTLWLAMTSGDVYALCPLLPQRWTPPPTLIPSLSASIVAKVAAAEDNPESTPEERLVAQQQLEWMSEIDNQEPKLVEEATGEATIEVYTRPSRPGLVPKLQGPFDFDLNPEDEQDDEVELKDIYVIGEKPRVADLMRGEEEELEMMKEDQHNGLSLNIICLLSTSGQVKICLDIDGVEAQWLPPRSKNKRLFAPPPEPPSLLTFQTFDTLKPAEVTPDGWPMFSEDATSPYSFYVTHPAGITYISLTPWVFRLESELQSDSEAGTEFRIDLLAKGQGSERDRIFTQTRTQSPLAAATSIDDPDLGYFILSATQTDPIALFFETPERPVVPKETSVVIPEHVEERPPSPYWEPRPLFHPAEALDKPSAVPAWIDNLRTGRRRPLLTQELRLSMATLEVFHDGHKVVSTEVSDINDAVAELFRKCEALQGELRDQIKKVNEVKNRIHTITGDDLSDDPPVSEDQLIKQRIRVARERQEELANRMERLRKKFGRTTTRELSDKEKAWIEEVQNMATSILGPEAGQGALATTPNLAKQPWKRLEEIKTLRNALMAEAEQLQKVGDDTEESTPASQMPSLKIPSEIRKAKMAQVMSLLERESALVDAVKARIERLSIG
Protein: Alpha2-adrenergic-like octopamine receptor, isoform B (A0A0B4KHD0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Tyramine/octopamine receptor
- G protein beta subunit 5
Sequence:
MDYSRLNANINTGNISTDDFLAVFSTGKPDNATLNPPLLSVDGQLTLPPGSGYVNVNDTIFFLNGSFYNSSLQLAAGFYNQSSASGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVKMPEGPLPKCELSEDIGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKKGTIPMPSSSGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTVLAYANPNGAGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSINVLNNNNGTVAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFDPSSSDSGVVSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQQQVVKSELEPAIPKTPKPRDPEKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACSSHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRILFKXCLAYVCCYRCVYASIEKATERAMGSTPMGYGHGMYQHYRR
Protein: LD28840p (Q95RH7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDVVKKVLVGNKNDDPDRKVVITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLKPNPKGSKGGKCCR
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2) (Centrosome-associated protein) (Q6QNY1)
Organism: Homo sapiens (Human)
Function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May play a role in cell proliferation.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15381421}. Lysosome membrane {ECO:0000305|PubMed:25898167}. Note=Localizes to the centrosomes in a microtubule-dependent manner. {ECO:0000269|PubMed:15381421}.
Interaction partners:
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- KxDL motif-containing protein 1
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- Dysbindin
- SNARE-associated protein Snapin
- Biogenesis of lysosome-related organelles complex 1 subunit 3
- BLOC-1-related complex subunit 7
- BLOC-1-related complex subunit 6
- BLOC-1-related complex subunit 5
- BLOC-1-related complex subunit 8
Sequence:
MAAAAEGVLATRSDEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLEAKYKKLEKR
Protein: Cholera toxin transcriptional activator (P15795)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Function: This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Transmembrane regulatory protein ToxS
- Outer membrane protein U
- Cholera enterotoxin subunit A
Sequence:
MFGLGHNSKEISMSHIGTKFILAEKFTFDPLSNTLIDKEDSEEIIRLGSNESRILWLLAQRPNEVISRNDLHDFVWREQGFEVDDSSLTQAISTLRKMLKDSTKSPQYVKTVPKRGYQLIARVETVEEEMARESEAAHDISQPESVNEYAESSSVPSSATVVNTPQPANVVTNKSAPNLGNRLLILIAVLLPLAVLLLTNPSQTSFKPLTVVDGVAVNMPNNHPDLSNWLPSIELCVKKYNEKHTGGLKPIEVIATGGQNNQLTLNYIHSPEVSGENITLRIVANPNDAIKVCE
Protein: Appetite-regulating hormone (Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (Q8AV73)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- G_PROTEIN_RECEP_F1_2 domain-containing protein
- Pro-glucagon
- Insulin
- Uncharacterized protein
- Agouti-related protein
- Peptide YY-like
- Cholecystokinin
- Pro-neuropeptide Y
- Somatotropin
- Motilin
Sequence:
MFLRVILLGILLLSILGTETALAGSSFLSPTYKNIQQQKDTRKPTARLHRRGTESFWDTDETEGEDDNNSVDIKFNVPFEIGVKITEREYQEYGQALEKMLQDILAENAEETQTKS
Protein: Pre mRNA splicing protein (Q97ZH3)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Interaction partners:
- Large ribosomal subunit protein eL8
- Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
- Ribosomal RNA small subunit methyltransferase Nep1
- Small ribosomal subunit protein eS6
- K Homology domain-containing protein
- Small ribosomal subunit protein uS4
- Probable tRNA pseudouridine synthase B
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS1
- tRNA pseudouridine synthase subunit A
Sequence:
MMKIYLIEHVIGAVAYDENGNIVDYITNPRDLGKITEELLNNEKGIPFSATVELLKKVNPQEVVVENEAEVPKLQALGYRVSYEPYSKVSRIFRESLPKVAIDIKFASNEEDYYNFLHELSLEYTRRKLRSAAQKRDLLAIQAVRAMDDIDKTINLFSERLREWYSIHFPELDKLIEDHEEYATIVSRFGDRGFLTIDSLKELGFNEQRINRILDAAKKSIGADISEDDLSAMRMIANTILDLYNIRRNLNNYLEGVMKEVAPNVTALVGPALGARLLSIAGSLDELAKMPASTIQVLGAEKALFRALRSGGRPPKHGIIFQYPAIHTSPRWQRGKIARALAAKLAIAARVDAFSGRFIGDQLNEQLKKRIDEIKEKFAQPPPKKPQQQKPQQPQKQQAKGKKGGKRRGKRK