wanglab/gogpt-training-data huggingface dataset:
Protein: Neuronal regeneration-related protein (Neuronal protein 3.1) (Protein p311) (Q80Z34)
Organism: Rattus norvegicus (Rat)
Function: May have roles in neural function. Ectopic expression promotes axonal regeneration. Augments also motility of gliomas (By similarity). May also have roles in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration (By similarity). Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MVYYPELLVWVSQEPFPYKEMEGGLTKGRLPVPKEVNRKKMDEPIAASLIPPGNHEPGSPAIGYLHPF
Protein: Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.-) (G8BGE3)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|RuleBase:RU362107}.
Interaction partners:
- Citrate synthase
- Isocitrate dehydrogenase subunit 2, mitochondrial
- Isocitrate dehydrogenase
- Isocitrate dehydrogenase
- Isocitrate dehydrogenase subunit 1, mitochondrial
- Isocitrate lyase
- 2-oxoglutarate dehydrogenase, mitochondrial
- NADH-quinone oxidoreductase subunit D domain-containing protein
- dihydrolipoyllysine-residue succinyltransferase
- Succinate--CoA ligase subunit alpha, mitochondrial
Sequence:
MLSASRTAIRTSNPRSVSIRGLASAINRDSKVHQNLLEDHSFINYKKHLENVEIVKARLNRPLTYAEKVLYGHLDDPHGQDIERGKSYLKLRPDRVACQDATAQMAILQFMSANLPQVATPSTVHCDHLIQAQVGGAKDLARAIDLNKEVYDFLASACAKYNLGFWKPGSGIIHQIVLENYAFPGALLIGTDSHTPNAGGLGQLAIGVGGADAVDVMSGLAWELKAPKIIGVKLTGKMSGWTSPKDIILKLAGITTVKGGTGAIVEYFGSGVETFSCTGMGTICNMGAEIGATTSVFPYNKSMDDYLEATGRSEIAQFASQYKNDFLKADDGCEYDQVIEIDLNTLEPHVNGPFTPDLATPISKMRETAIANDWPLDVRVGLIGSCTNSSYEDMSRAASIIKDAEAHGLKAKTLYTVSPGSEQVRATIARDGQLKTFEDFGGVVLANACGPCIGQWDRQDVKKGEKNTIVSSFNRNFTSRNDGNPATHAFVASPEMATAYAITGDLGFNPITDYLVDSEGKEFKLKEPSGLGLPPKGYDKGENTYQAPPQDRASIDVVISPTSDRLQKLKPFKPWDGKDAERLPILIKAVGKTTTDHISMAGPWLKYRGHLENISNNYMIGATNAENGKANEVKNHYTGKWDGVPQTAAALRDSGHKWVVIGDENFGEGSSREHAALEPRFLGGFAIITKSFARIHETNLKKQGLLPLNFTNVADYDKINPTDEIDLLGLTELAPGKNVIMRVHPKDGEAWETELSHTYNDEQIEWFKYGSALNKMAAVAAEKAAAAGKK
Protein: Dual specificity protein phosphatase PHS1 (EC 3.1.3.16) (EC 3.1.3.48) (Protein PROPYZAMIDE-HYPERSENSITIVE 1) (Q75QN6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable dual specificity phosphatase that binds and dephosphorylates MPK18, modulating the organization and dynamics of cortical microtubules. Acts as negative regulator of abscisic acid (ABA) signaling during seed germination and light-induced stomata aperture.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19392697, ECO:0000269|PubMed:20224945}.
Interaction partners:
- Inositol diphosphatase DSP3
- acid phosphatase
- Phosphatidylglycerophosphate phosphatase PTPMT2
- Probable protein phosphatase 2C 10
- Protein-tyrosine-phosphatase PTP1
- Metal ion-binding protein
- Inositol diphosphatase DSP4
- Inositol diphosphatase DSP2
- Mitochondrial carrier protein MTM1
- Protein POOR HOMOLOGOUS SYNAPSIS 1
Sequence:
MAEPEKKRDQPFSQEKDEEKDLYLVHDEHESPLPLTVTSRVLYMLGDIASGPAYRFTQWLDLVRKRSATYGSSGFPHRLHRIDDMVTSAGERNTDPKSPPSRQSSEISLWERLGKASTVDIDSSCFSWNMLSSLHHTEHSSSTDHSEEDQSKPLEVTVNSGGVVFFALFNSSSSEDASRKEEAAVIKFASSRMATQSERLGYEFSKWLGVQIPQARVIHSCNPEWTLIKEATEKAQAKATSEGDEVGEMTCSELLEALELSRCLLLMSYVHGCPMLESMSSFETEEKAERAAAALGRILVLDLVIRNEDRLPCRQLRWRGNPANLLLTDRIVSSAKHHECSFDEAFDSAIKRYHPKDYRSIQRERRASSVDSRSRLSISDQMLVSQASDFSDITESPRSYDTGLMSPMSDRSVAADFHLVAIDSGVPRRPPAGKRASDQEIYPRLVELLLNSSQYSSNLLHEITEGSLGYPQAEDGEETSNVRSVVTPVVREFRNGFRAGLRDLQEFHIFLVTLHQKLDVLLRAFFSMMDKTMCADFDREDFAVPESPSHTHGHEVNHYPSPSKDRVPSDNSSDHSESDMQKSVPRTPNSENKEDGSSPKSRESWHGRSGKGGESLSSQRLAAKLRDFHKFAKVDAESNKELDQWNETLRNEVMKLCQENGFNTGFFEGSDNNSCTDAYELKVRLEHILERISLISKAANTEKPSMIQENLFIGGGLAARSIYTLQHLGITHVLCLCANEIGQSDTQYPDLFEYQNFSITDDEDSNIESIFQEALDFIKHGEETGGKILVHCFEGRSRSATVVLAYLMLQKKLTLLEAWSKLRKVHRRAQPNDGFARILINLDKKCHGKVSMEWRQRKPTMKVCPVCGKNAGLSSSSLKLHLQKSHRKLSSGSVDSAMNMEIQKALEALKLSTGRGSSASSNSFQSHPG
Protein: Retinol dehydrogenase 1 (A0A286Y8B5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MVFCCADLLCSCWCSLAVIALIAAVWFFRDSRQISGIHEKHVLITGCDSGFGNLVARQLDRQGFLVIAACLTETGASKLRATASPRLKTLQLNVTDSTSINRALEYVRRETGGKGLWGLVNNAGVSVPIGPMDWMQLHDFKKVLDVNLTGVIAVTLKFLPLLKKAQGRVVNVASILGRLSIIGGGYCLSKFGVEAFSDSLRRDMVHFGVKVSIIEPGFFKTQVTDLGLIEDDLKKRWSNLPEQVRRDYGDSYLQEYLKVLEFSHKMLASSDLSKVTSCMRHALSARHPRTRYAAGWDAKFLWIPLSYLPTCVVDIITKALVPSSKPL
Protein: RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (P87115)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1297 and 1815 in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein tan1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03211, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Ribosome biogenesis protein bms1
- Ribosome biogenesis protein enp2 homolog
- U3 small nucleolar RNA-associated protein 20
- U3 small nucleolar RNA-associated protein 22
- Periodic tryptophan protein 2 homolog
- Probable nucleolar complex protein 14
- U3 small nucleolar RNA-associated protein 21 homolog
- Uncharacterized protein C13G1.09
- Probable U3 small nucleolar RNA-associated protein 7
- Ribosomal RNA-processing protein 7
Sequence:
MPKKALDSRIPTLIKNGCQEKQRSFFVVVGDRARDQVVNLHWLLSQSKVAARPNVLWMYKKDLLGFTSHRKKRENKIKKEIKRGIRDPNSEDPFELFCSITNIRYCYYKESEKILGQTYGMLVLQDFEALTPNLLARTIETVEGGGIVVLLLHKLNSLKQLYTMSMDIHSRYRTEAHSDVTARFNERFILSLGNCENCLVIDDELNVLPISGGKNVKALPPTLEEDNSTQNSIKELQESLGEDHPAGALVGVTKTLDQARAVLTFVESIVEKSLKGTVSLTAGRGRGKSAALGLAIAAAIAHGYSNIFITSPSPENLKTLFEFIFKGFDALNYEEHVDYDIIQSTNPAYHNAIVRVNIFRDHRQTIQYISPEDSNVLGQAELVVIDEAAAIPLPLVRKLIGPYLVFMASTINGYEGTGRSLSLKLLQQLREQSRIYSGSGNNKSDSQSHISGRTLKEISLDEPIRYAMGDRIELWLNKLLCLDAASYVSRMATQGFPHPSECSLYRVSRDTLFSYHPISEAFLQRMMSLYVASHYKNSPNDLQLMSDAPAHQLFVLLPPVDLKNPKLPDPICVIQLALEGSISRESIMNSLSRGQRAGGDLIPWLISQQFQDENFAALGGARIVRIAVSPEHVKMGYGTRAMQLLHEYFEGKFISASEEFKAVKHSLKRIGDEEIENTALQTEKIHVRDAKTMPPLLLKLSELQPEPLHYVGVSYGLTPSLQKFWKREGYCPLYLRQTANDLTGEHTCVMLRVLEGRDSEWLGAFAQNFYRRFLSLLGYQFREFAAITALSVLDACNNGTKYVVNSTSKLTNEEINNVFESYDLKRLESYSNNLLDYHVIVDLLPKLAHLYFSGKFPDSVKLSPVQQSVLLALGLQYKTIDTLEKEFNLPSNQLLAMLVKLSKKIMKCIDEIETKDIEEELGSNKKTESSNSKLPEFTPLQQSLEEELQEGADEAMLALREKQRELINAIDLEKYAIRGNEEDWKAAENQIQKTNGKGARVVSIKGEKRKNNSLDASDKKTKEKPSSKKKFRK
Protein: Patatin-like phospholipase domain containing 3 (EC 3.1.1.3) (Zgc:92195) (Q6DHN9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MFDLKEGWNLSFAGCGFLGIYHIGVASCLLEQAPYLIRGATKIYGASAGALTASVLTTEACIEKCCEDVINVAKEARKRNLGPLHPTFNIVKVIRGGLYRDLPSNAHTLSSGRLCVSLTRVMDGQNVLVSDFSSKEELIQALICSCFIPVYCGLIPPAFRGVRYVDGGISDNLPQSELKNTITVSPFSGESDICPKDNSTSFHELRFTNTSIQFNLDNAYRLSKALFPPEPKVLAEMCQSGYKDALRFLQENNLLQAACPGVDMALIQATPTCCCPGKKNPVVEETTKEWVLRRLRLLRKHHWWLDEQIVDNLPTPIKKVFCDACREKHGLLAQVTGLLPVRVASYMLLPYTLPVESAYSAAQRFWEWIPEVPADVRWLTEVAGGVYRLAWKGAASEANSGAPLRRCVSEPPMADLQMPIKDCAGHIPHSASTLDSYKWTFPNNIHTTSSIDCPESPVSEPRQMSFFVGSPNN
Protein: Ras-related protein Rab-25 (EC 3.6.5.2) (Q9WTL2)
Organism: Mus musculus (Mouse)
Function: Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, pseudopodium membrane {ECO:0000250|UniProtKB:P57735}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P57735}. Note=Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips. Colocalizes with RAB11A in subapical vesicles (By similarity). {ECO:0000250|UniProtKB:P46629, ECO:0000250|UniProtKB:P57735}.
Interaction partners:
- Rab11 family-interacting protein 2
- Rab11 family-interacting protein 1
- Phosphatidylinositol 4-kinase beta
- Rab11 family-interacting protein 3
Sequence:
MGNRTDEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEACMFAENNGLLFLETSALDSTNVELAFQTVLKEIFAKVSKQKQNSTRTSAITLGNAQAGQDPGPGEKRACCISL
Protein: DUF3159 domain-containing protein (O07195)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MNANRTSAQRLLAQAGGVSGLVYSSLPVVTFVVASSAAGLLPAIGFALSMAGLILLWRLLRRESARPVVAGFCGVAVCALIAYLVGQSKGYFLLGIWMSLLWAVVFTLSILIRRPIVGYLWSWLSGRDRAWRDVSRAVFAFDVATLGWTLVFAARFIVQRHLYDADKTGWLGVARIGMGWPLTALAALATYAAIKAAQRAILASHDAAAVGGAAEFDADAGRE
Protein: DNA primase large subunit (DNA polymerase alpha:primase complex p58 subunit) (DNA polymerase-primase complex p58 subunit) (Pol alpha-primase complex p58 subunit) (DNA primase 58 kDa subunit) (P20457)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48.
Interaction partners:
- DNA polymerase alpha catalytic subunit A
- DNA polymerase alpha subunit B
- DNA primase small subunit
- DNA polymerase epsilon catalytic subunit A
- DNA polymerase delta catalytic subunit
- DNA polymerase epsilon subunit B
- DNA polymerase delta small subunit
- Replication factor A protein 2
- DNA polymerase zeta catalytic subunit
- DNA polymerase delta subunit 3
Sequence:
MFRQSKRRIASRKNFSSYDDIVKSELDVGNTNAANQIILSSSSSEEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRNKSIKEIETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRFNMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQYFQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQYLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSRQLQKKQQKLEKEKLFNNGNH
Protein: RH48823p (Q8IGD5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
PSRRASSGVGPTNAAATVAAATGAVGAVNPSNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQRPASATQKMLTTADTTLNSPAKPRTATKYDPTNGNRTVSGTSGIIPRRSTTLYEKTSSTEKTNVIPAETKMASAVKSSRHFPRNVPSRSTFHSGQTRARNNTALEYSGTSGASGDSSHPGRMSFFSKLSSRFSKRPNQ
Protein: Kinesin (Q388V4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSPMFSCSPRTPSIVLTPREVSVEGRLTSHCIPTFDLLMVNRNGEEVCAVREGSAHIEPHRRDALVEERNSGNLYCGGGAGDDDEALRSKLLTETAYSQSAVFTSGSVEEHPAHFETLLVRGCPVNADTSHNDPTQEKLRSLSPVKGVYATSETITEIANDGHRPPLSFMLTGGRNAKRRRRGHHTSAITPVQASSPSGCRYMWEEGSQRFGGALDFSGSSIMAVGQGGVNVEGNGTADWKRRCLFAEHQLAVAIRCLWEYHNTMSAQRQHVLSPADVDDIQPFPPTSGVSTSAVPNVNWGQQVKEDLDGEGGITKGETAAYGYEQGADVRTSGTDEQPSGVASDECSVQRPTALPFCCAPGAVAPHPCSWAISTEGAEAKLVGEMDEWLAREKVVRLKQELLATALRQARLTAMRTMQRIEERELEFKAVISRCNAVKTALLESEAQVKRLRELDQRRVEENKRLQQRISELKAELRGCESNIDSNGGCFTDAVGLDDGDDPLSMSVSQTQDIETQLLHVVAALQCGESRRKWVADQLSHVLRRVNMGVCNKGVTSVSDHPKLMALVESLEALKSSEIVMLSEECGTPVVFRGGSDASTTTLKGCESTAELLHCAGECVAQLEKRMRNLYTHRSTLRVEMKATPVAYDVCEREECQLAQRPHLQPKSVEPQRNTCVTGCAAKEEITNNVEENVCPSHRNDTEAQLSVDSEFLGVRNRVPVLHSLYDGGLAHLQKHLEQQLDEFSHTLRLMLTEAIRWLFQQQSMNVVENKGSPAVVRIQHSRMPKGPFEEQKENQPMQQVGHGFPIQPLSVSAVKSGAKNRIPGLFIHSQGQSKWTPMPSPKPGGGVAYPRETPRSLPPSPLSGRMTLPPFVFEDFAGRRSTESDRDASADGFTAARSQLGIDVVAPLGRQQVVTGELTQRRSVSSPGRCDSLYIQSCNATNSNSPRLFPLSQNDPNLAGRWASVRLCRR
Protein: LD40504p (Poly-glutamine tract binding protein 1) (Q9VBY6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Thioredoxin-like protein
- EG:100G10.1 protein
- Ataxin 1
Sequence:
MSLPAALLQRLKKRGLVTKQSGAAPISEAIEEIIAENYDDDDKSGPYPYKEDTSPEPKRRSVEEKFWSHRIKERIGVNESYHGYKLCPNKYNIYHKCSLYCVNKFNSSPLSQPSHRYLKRYKRLLRKYPLEAGWKDVYDKGCKAFYFYNSTTQTVSWLPPSHPKARITNSAAVFRRQLANSNDEFNFDTNMVQPKSSNQNEPDEPDVFVPAKKQKSRDLERKIQRRRRNDN
Protein: Collagen type IV alpha 2 chain (A0A8I6AHV3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
Interaction partners:
Sequence:
MDRVRFSASGLPLRGWLLLATVTVGLLAQSVLGGVKKSDVPCGGRDCSGGCQCFPEKGARGQPGEVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGTGGFPGLPGPQGPKGQKGEPYALSKEDRDKYRGEPGEPGSVGYQGPPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSDITLIGPTPSTYHPDMYKGFPGLDGEKGVSGQKGSRGLDGFQGPSGPRGPKGERGELGPPGPPAYSPHPSLAKGARGDPGFQGAHGEPGSRGEPGDPGPVGPPGLSIGDEDSKRGLPGEMGPKGFSGEPGPSAYYPGPPGADGKPGPQGLPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGGRGQKGWKGEAGDCQCGQVIPGLPGLPGPKGFPGVNGEFGKKGDQGDPGLHGIPGFPGFKGAPGIAGAPGPKGVKGDSRTITTKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGTPGTKGFPGEVGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGLPGTPGQADCDTGVKRPIGGGQQVVIQPGCVEGPAGSPGQPGPPGPTGAKGIRGIPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGAPGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGARGDAGLPGQPGLKGFPGEIGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLSGPPGQHGFPGAPGREGPLGLPGSPGLGGLPGDRGEPGEPGEPGPVGMKGVSGDRGDAGVSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRPGFPGIKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPGMKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGLSGIPGLPGRPGFIKGAKGDIGVPGTPGLPGFPGVSGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGVTGIPGLKGLFGEKGAEGDVGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGRPGIPGIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGAPGQKGEQGIPGERGPVGSPGLQGFPGISPPSNISGLPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGEKGWVGDPGPQGQPGVHGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTMGPQGRRGLPGALGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPIGQEGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQNFQSTPSADTLKAGLIRTHISRCQVCMKNL
Protein: Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2) (P25801)
Organism: Mus musculus (Mouse)
Function: Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
Subcellular location: Nucleus {ECO:0000269|PubMed:9391090}.
Interaction partners:
- Erythroid transcription factor
- T-cell acute lymphocytic leukemia protein 1 homolog
- LIM domain-binding protein 1
- Transcription factor E2-alpha
- Protein lyl-1
- Endothelial transcription factor GATA-2
- Runt-related transcription factor 1
- Zinc finger protein ZFPM1
- Core-binding factor subunit beta
- Transcription factor 12
Sequence:
MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGII
Protein: Protein kish (Q9VWH8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the early part of the secretory pathway.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Immediate early response 3-interacting protein 1
Sequence:
MSALFNFHSLLSVILLLICTCAYLRSLFPSLIDRNKTGFMGTFWKLARIGERKSPWVGAACLIMAFTVLFWS
Protein: UV excision repair protein RAD23 homolog B (HR23B) (mHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58) (P54728)
Organism: Mus musculus (Mouse)
Function: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome.
Subcellular location: Nucleus {ECO:0000269|PubMed:15336624}. Cytoplasm {ECO:0000269|PubMed:15336624}.
Interaction partners:
- Centrin-2
- Peptide-N
- DNA repair protein complementing XP-C cells homolog
- DNA repair protein complementing XP-A cells homolog
- 26S proteasome non-ATPase regulatory subunit 4
- DNA excision repair protein ERCC-1
- 26S proteasome regulatory subunit 4
- UV excision repair protein RAD23 homolog A
- E3 ubiquitin-protein ligase AMFR
- DNA damage-binding protein 1
Sequence:
MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILSDDTALKEYKIDEKNFVVVMVTKPKAVTTAVPATTQPSSTPSPTAVSSSPAVAAAQAPAPTPALPPTSTPASTAPASTTASSEPAPAGATQPEKPAEKPAQTPVLTSPAPADSTPGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAVVDPPPQAVSTGTPQSPAVAAAAATTTATTTTTSGGHPLEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGSQGGGGGGGGGGGGGGGGGIAEAGSGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED
Protein: Nucleosome assembly protein (Q4GZ00)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Histone H2A
- Histone H3, putative
- Histone H3 variant
Sequence:
MGSPAAPYNSAVCAVQKLINKLEDEMHEAVTKVLVENNIKLNEHYSARHEVITNAIKNGKLPTTFWADAIIAVLRDAHVEEDRDGSRAAGNDAEDDDDDGNQLGTFDEALLRKHLKDMMVTYKETGSRLSLTFSPNPFFEETELWIEENQLNNEGSKNNDDDNNNNNNDSDGGGGGDFYKTYEVSDITWKPDHGPNFDDNDGDGGGGEKRSGSKRGRSNMDPTRHGWSFLNMFSKIPPHPLDDYYDDDFYDDNDDDDDDDDKKWIEEAIDIWEEDMDEREQLFRFLVREVWSDPLEAAAEKGSDNGAGTSPEKPNKHE
Protein: DNA topoisomerase (ATP-hydrolyzing) (EC 5.6.2.2) (Q6P0S6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAYQFTEVDKLREALCESLETVDRCQEDISSQDVLTRIEKVIERIVIDVSKGEAPVLRLINRSCWNNVRFQESVGLVLKDDVSPKYLHCGKPTTATKFALILKILSIIYKLVQSDSYATKRDIYYNDPQLFGSQRMLDSIVDDISCMLKVPRRSLHILATSKGFISGDLCYLEEDGTKVDCNSSSTAVSVSSNVNGIRNIVSSAKFILIVEKDATFQRLLDDDFCARLSPCIIITGKGVPDVNSRLMVRKLWDALHVPVFALVDADPHGIEIMCIYKYGSVSMAFEAHSLTVPSVLWLGLLPSDIQRYRVPEEALIPFAKADERKISSLRSRSYITCQPTWEREVETMQNLKRKAEIQCLASIAPHFLTRVYLPNKLRYGGWI
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q57YX3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MQQNIHSFTPTNGKDRCKLCLSYCGPIYLVVVILSFLGAYAAFFIGLCLRYPTSWKLAVCISCLFTGAVLAGILIFTLLRAVFTPAGYVPQSPWQYPPRYIGECPGFVPPSGEGVGENPNTVRQLDRHNQLRYCTACKQFKPDRAYHCESCERCTFDFDHHCPVLNNCIGRGNYKMFVLFLCYVPIVGCVLGGLMFVGFFVVDEAEPAVAWMVFAMIMMIFCAVIGIFGCVHLCWLCRGESTMGRHVSSFNKQRGRSKEERAREREEHCNAVCGVRRVWWRLVMPVLPLREEAASLV
Protein: At5g02890 (HXXXD-type acyl-transferase family protein) (Q9LYZ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Wax ester synthase/diacylglycerol acyltransferase 9
- 3-ketoacyl-CoA synthase 5
- Non-specific lipid transfer protein GPI-anchored 2
- Protein ECERIFERUM 26
Sequence:
METKIPKSMIAGVQTVMPVEVTQHREIRSVSVVDPVGVGIFRRTVNIVTYYKEAGDSGGERGWLVAGWIKESLGRALTEQPMLSGRLRRRKTAGNDGLELVANDSGVRMVEAKFPASLPEFLEMAKRDKSRAEAETVFWKDIDEDEPQYSPLFYVQVTNFESGGYSIGISCSILIADLFLETGFLTKWAQIQSSLAQTTLKPVFHLPSLKQDFGNFLTEFFRSASVLDRGEPIAFRAKTCLKISPACIVTSKRTSGDVFLFIKEQSSGENSTGCDGTKVEIHSSDEVIKGCDCGRDSEETNDGVLDKSLSFGERLEVTSCWVGCVSKGVVFVFPSTFGDAKSLAKFIVALPKE
Protein: Small ribosomal subunit protein uS12 (30S ribosomal protein S12) (BS12) (P21472)
Organism: Bacillus subtilis (strain 168)
Function: With S4 and S5 plays an important role in translational accuracy.
Interaction partners:
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein bL17
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL1
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS13
- DNA-directed RNA polymerase subunit beta
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL30
Sequence:
MPTINQLIRKGRVSKVENSKSPALNKGYNSFKKEHTNVSSPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVENRAQGRSKYGTKKPKAK
Protein: Leucine zipper putative tumor suppressor 2 homolog (Protein LAPSER1) (B8A6E8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03026}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|HAMAP-Rule:MF_03026}.
Interaction partners:
- Arginine and glutamate-rich protein 1-B
- Serine/threonine protein phosphatase 2A regulatory subunit
Sequence:
MALVQALPVPTDHPKPSTDVQQCCSVSHSPTVDVTGTMGSVSSLISGRTYQERHCRAASDFGARYRKPTPATSCFRQQEGTLRSSSSQEQLLNSQPPLPAKNKSSALISAGNGNYGYLSDEPVGDWNDNHVSTCSPSSDTEEPSDNRGMNGNIGGPPPKLVPVSGRLEKVSMEKILIRPTAFKPVLPKNRNSVQYLSPRSGGSLSESQGSLNLLLPGTGAGSGCQEKRNSYSGGRNARSSQSCTMSDSGRNSLSSLPTYSSTGYSLTQSEVPNGHMETTRSGVGHGHSNSDSGRSSSSKSTGSLSGRGQPLSDSGSCGRSPAPGEGYEGVIRELEEKLRERDLELQQLRDNLDENEAAICQVMILDFYQFLQQFDRKLSYTIQLKSSVFSMQVYEEKQKRCEQEMEDLRQSCASKMKQVQLKAQRAQQVLQLQVFQLQQEKKKLQEDFSQLLQEREALEKRCASFEREQTQFGPRLEETKWEVCQKSGEISLLKQQLKDVQADLGQKASEIVALKAQLREARSELQASQARSQEAHATARTRTLELEVCENELQRRKSEAELLREKMGRLEEESLRLKEAMAVPTPQTLPSKGQSMSLPLPQSRGGIGHGISPAFRDNSSEEQLLAYESDEAKAQRQSVDVLHGLRQQVDRLRAELMYERRRSEDQLEGFEDERRVWQEEKDKVIRYQKQLQQNYIQMYRRNRDLERVMRELSLELENRDMEEFDMRSNEIHFEEITATEI
Protein: Zgc:110113 (Q568S8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNLRSYRSSTVLPMETSSSSSDDSCDSFGSDGFGNSKRPQRQTRSSTQMEKVFNVLPVTEEEDACSGFESELNDELTEMKMDSDAEACSPPRKTRKSFTLRVAMKFPTKRSSPSKPVKPEPKPKAETKDPESDSEGENFMLKRALNIKENKAMLAKLMAELDKVPGLFPGRAALTPGNVVRRVPRRSLEPIAARRRNPERTSRPHTRSRSLVDGPPSPPPEDEEEDKYSLVRRSRGYEDVDEEEKEPRRRSYNSSLTIPHVVRPVEDITEAELENICINVREKTYNRATGSTCHQCRQKTTDTKTNCRNSECVGVRGQFCGPCLRNRYGEEVRDALLNPEWLCPPCRGICNCSFCRAREGRCATGVLVYLAKYHGYDNVHSYLKSLKKELEESE
Protein: Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16) (P13681)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Essential role in cell cycle control. PP1 is perhaps required for exit from mitosis.
Subcellular location: Nucleus.
Interaction partners:
- RNA polymerase II subunit A C-terminal domain phosphatase ssu72
- Uncharacterized WD repeat-containing protein C824.04
- Protein phosphatase 1 regulatory subunit SDS22
- Cleavage and termination factor 1
- Endoribonuclease ysh1
- Protein cft1
- Cleavage factor two protein 2
- Polyadenylation factor subunit 2
- mRNA cleavage and polyadenylation specificity factor complex subunit pta1
- mRNA 3'-end-processing protein yth1
Sequence:
MSNPDVDLDSIIDRLLEVRGSRPGRQVQLSEDEIRFLCNKAREIFISQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLEVICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLNSMDQIQRIMRPTDVPDTGLLCDLLWSDPDKDLTGWGDNDRGVSFTFGPDVVSRFLHKHDMDLVCRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKQRYGYQGSSQNWHMTPPRKNKTGNSK