wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein (Q584T7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLRVVSRKICTTIVRRCRGGSVLEEIFAELAACDVAQRSAQPTPQVDFARREKCRGDFNSGAGKCNAVTSPGRSPESEDRDIRAETSKQKHLQRQLQEVWDRVAMAKVEEEKEEGVRRRSRYVVSPPAILHHSTAELVQENSPQHFVPAEDSSGKLSALPHVESPGSVAVVTLVGRVLSAVGSHGSSETSRDDRDLLTDEDELHARFLVEYNVPFRTLKPVVVQVRCYGATLLSFAERYVKKGDVVHVLGHVLPLEVRSPEDPVLCVCALPFGGNVSVVLGTECVAE
Protein: Vesicle-associated membrane protein-associated protein scs22 (VAMP-associated protein scs22) (Q10484)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Vesicle-associated membrane protein-associated protein (VAP) implicated in maintaining the cortical endoplasmic reticulum (ER)-plasma membrane (PM) attachment. ER-PM contacts function to modulate the distribution of contractile ring components to ensure robust ring assembly. ER-PM contacts function also in controlling exocytosis and maintenance of cell polarity regulating cell shape. VAPs play an important role in regulating eisosome assembly. VAPs also contribute to ER-phagy by tethering atg8 to the ER membrane, but also by maintaining the ER-plasma membrane contact (Ref.7).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23041194}; Single-pass type IV membrane protein {ECO:0000255}. Note=Localizes at the cortical endoplasmic reticulum-plasma membrane contact sites. {ECO:0000269|PubMed:23041194}.
Interaction partners:
- Oxysterol-binding protein homolog C2F12.05c
- Oxysterol-binding protein homolog C23H4.01c
- Uncharacterized protein C691.05c
- Uncharacterized protein C962.01
- Oxysterol-binding protein homolog C23B6.01c
- Reticulon-like protein 1
- Meiotically up-regulated gene 190 protein
- Uncharacterized protein PYUK71.03c
Sequence:
MALECDSTIVFPRPLTRLVKCDLELRNTAPYPIGFKVKTTAPKQYCVRPNGGRIEANSAVSVEVILQPLDHEPAPGTKCRDKFLVQSTELKPELQGMDIADIWTQVSKANISERKIRCVYSEGPSTANAHANAHHQPAQTTTTSIPTSATDNYTTVNGNVNQSYSKGIDGTALPSTHANPVAAPSTATTQHTQLPKTSAVSHQKPHEAPSTAVKAPTATVAENEPYPKPQSVPTTTSPNNENNALRSTANVINNTRQSTATSPSMFAGNSGNQIGLARVSSSFGRPTSGAKVVPQIHNTVTVQTAFLLAIICFLIGLLF
Protein: Vacuolar membrane protein YOR292C (Q08743)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Uncharacterized protein YIL067C
- Protein UIP5
- Uncharacterized vacuolar membrane protein YNL115C
- Putative magnesium-dependent phosphatase YER134C
- PMA1 stabilization in the Golgi protein 1
- Uncharacterized transcriptional regulatory protein YNR063W
Sequence:
MPLQLFGRDQIVVHYDNGNMSNDDQNHQSVLGSWTRRAAAALRTLMNKRIQRITLTHWLLLVIWVTSLWKFTSHYRQLYANSAVFATLCTNILLFGISDILAQSIACFYSYHVDPIPQILNDTFHHVQNNRDVENGGGYESDELSIFNDFTSEHSSYTDNDDYPELDRPLATFKTDTFDFFRWGCFMFWGFFISFFQAPWYKFLNFFYTEDPTVVQVFERVLSDQLLYSPISLYCFFMFSNYVMEGGDKDTLGKKIQRLYISTLGCNYLVWPMVQFINFLIMPRDFQAPFSSSVGVVWNCFLSMRNASK
Protein: Cytochrome P450 2A2 (EC 1.14.14.1) (CYPIIA2) (Cytochrome P450-UT-4) (Testosterone 15-alpha-hydroxylase) (P15149)
Organism: Rattus norvegicus (Rat)
Function: Highly active in the 15-alpha-hydroxylation of testosterone.
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Interaction partners:
- Cytochrome P450 3A1
- Cytochrome P450 1A2
- Cytochrome P450 3A18
Sequence:
MLDTGLLLVVILASLSVMFLVSLWQQKIRERLPPGPTPLPFIGNYLQLNMKDVYSSITQLSERYGPVFTIHLGPRRIVVLYGYDAVKEALVDQAEEFSGRGELPTFNILFKGYGFSLSNVEQAKRIRRFTIATLRDFGVGKRDVQECILEEAGYLIKTLQGTCGAPIDPSIYLSKTVSNVINSIVFGNRFDYEDKEFLSLLEMIDEMNIFAASATGQLYDMFHSVMKYLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSPRNFIDSFLIRMQEEKYVNSEFHMNNLVMSSLGLLFAGTGSVSSTLYHGFLLLMKHPDVEAKVHEEIERVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDVFPIIGSLMTEPKFFPNHKDFNPQHFLDDKGQLKKNAAFLPFSIGKRFCLGDSLAKMELFLLLTTILQNFRFKFPMNLEDINEYPSPIGFTRIIPNYTMSFMPI
Protein: ComP-specific O-oligosaccharyltransferase (ComP-specific O-OTase) (EC 2.4.-.-) (Q6F7F9)
Organism: Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Function: Specifically catalyzes the glycosylation of the pilin-like competence factor ComP.
Subcellular location: Cell membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Polysaccharide export protein
- Pilin-like competence factor ComP
Sequence:
MNSIFKKIKNYTIVSGVFFLGSAFIIPNTSNLSSTLYKELIAVLGLLILLTVKSFDYKKILIPKNFYWFLFVIFIIFIQLIVGEIYFFQDFFFSISFLVILFLSFLLGFNERLNGDDLIVKKIAWIFIIVVQISFLIAINQKIEIVQNFFLFSSSYNGRSTANLGQPNQFSTLILITLFLLCYLREKNSLNNMVFNILSFCLIFANVMTQSRSAWISVILISLLYLLKFQKKIELRRVIFFNIVFWTLVYCVPLLFNLIFFQKNSYSTFDRLTMGSSRFEIWPQLLKAVFHKPFIGYGWGQTGVAQLETINKSSTKGEWFTYSHNLFLDLMLWNGFFIGLIISILILCFLIELYSSIKNKSDLFLFFCVVAFFVHCLLEYPFAYTYFLIPVGFLCGYISTQNIKNSISYFNLSKRKLTLFLGCCWLGYVAFWVEVLDISKKNEIYARQFLFSNHVKFYNIENYILDGFSKQLDFQYLDYCELKDKYQLLDFKKVAYRYPNASIVYKYYSISAEMKMDQKSANQIIRAYSVIKNQKIIKPKLKFCSIEY
Protein: Putative electron transport protein YsaA (P56256)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized lipoprotein YsaB
Sequence:
MNRFIIADATKCIGCRTCEVACAVSHHENQDCAALSPDEFISRIRVIKDHCWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQTRCIGCKSCMLACPFGAMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV
Protein: Expressed protein (TRIGALACTOSYLDIACYLGLYCEROL-like protein) (O80503)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized protein At4g28440
- Chloroplastic import inner membrane translocase subunit HP30-2
- Dephospho-CoA kinase
- ABC transporter G family member 7
Sequence:
MANLNSAIDSVFWDQNVSSPQTLEGTARSVPGEPFPLDGARASRSHRIQQLSLLREGFPLGIIPSLAPASDKRLGSFSLNSLLLSPSSNNWWLGLVGQFKPKKLFADIKADISNAEEWDLQVVKDTAKHIVDKSLYSIGLWTQIALGTSSSLLLSTERLGDKNGLRNKLMLVHPLEKHDLTVEAAWPDLFLDNKGRFWDVPESLNVDVSSLVPESGVRYRFGLHKSRGNPQPVNAAGVESGSDAPTSLMPGLCAKAAVSYKVNRDLWRPQEKEGNTEEEDKPVFLPYDLRLKEPHAAISGIVGSSLAAWITGRGMLVNGKKRSPISADVFGSACYTFQKGRFSKLYGDLTRVDARVDLPSAFALAKKLFHASSNNSDDTLWSPRLNLIFQQQVAGPIVFKVDSQFQVGAARMEDVIYSLNYSLRLLESGKIVAWYSPKRKEGMIELRVFEF
Protein: procollagen-proline 4-dioxygenase (EC 1.14.11.2) (Q8STH1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
Sequence:
MLFWRLVLLGMLYLSLSFGQLRENNAQQRFARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKWGVFKMMKRRQEYKSSMEIFANPIDTFSLIRHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFDFIDAAEGIRKMQATYQMFSSDIAKGLLDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQTDMELLRGPKLADLCRILGQVQMKQRNHEGALQAYQVALKLSPHDPEIYEEYRILEKRDLTLSDIEPIEQDKDNSHERLVLPPCCSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLLHDMISQKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFNDTTKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKNRFNGTSDRIATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWINDMGQEFTRPCVESSLSSKEVLSAERLII
Protein: Gamma-tubulin complex component (Q95SR3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000256|RuleBase:RU363050}.
Interaction partners:
Sequence:
MGMEDDLLLVEIFNKLQSCPLYQLLLEHALESGETQDLLCSVNTLSEMLTSNNEIQLPSLHDELFTQFFAQLKVYCGADNTDYEDEPEPDKDYEDLTVCNRQGIRNHELFAIFTQPLVEQRLERQRERLKSNPVLMANILKRLERSTCLQLKSELPEALREILRRRQWLANEYAIRAYCKETQVAEKMRFLRHTMLLEKYYLFVPYYNALFVRMEKNNSWALGSVLTSKLCAVLLPHYPQLAHYLHVKLISQINSNSIKVYEALEAIELDFERPMAMHQWYILTPAHMQDYNSVWRLMLKVKWAVWKLENMQFLRRARFNPCAPLDLIGLTIRRLEIVRFWLIFLINNLHAHIMEAVSRQFELRIGECKNVRELRIMHDEHLAWLKTHCMLTDEFKAFRVALDQIFHLVYVLDMEWTTCASCMHDHDALCLDVTISDDGIDDSETQRRSLEYLALNQVAEIELTYIRCHQMLADILNTLVHQNDHGFLSALEETINSSVPH
Protein: Nuclear transcription factor Y subunit B-8 (AtNF-YB-8) (Q8VYK4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Nuclear transcription factor Y subunit C-1
- Nuclear transcription factor Y subunit A-1
- Nuclear transcription factor Y subunit C-9
- Nuclear transcription factor Y subunit C-2
- Nuclear transcription factor Y subunit A-9
- Nuclear transcription factor Y subunit C-4
- Nuclear transcription factor Y subunit A-2
- Nuclear transcription factor Y subunit A-5
- Nuclear transcription factor Y subunit A-10
- Nuclear transcription factor Y subunit C-10
Sequence:
MAESQAKSPGGCGSHESGGDQSPRSLHVREQDRFLPIANISRIMKRGLPANGKIAKDAKEIVQECVSEFISFVTSEASDKCQREKRKTINGDDLLWAMATLGFEDYMEPLKVYLMRYREMEGDTKGSAKGGDPNAKKDGQSSQNGQFSQLAHQGPYGNSQAQQHMMVPMPGTD
Protein: V-type proton ATPase subunit C (A8KA87)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVSVVDTIAKQLAQIEMDLKSRTAAYDTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEYLVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKAKENKFTVREFYYDEKEIEREREEMARLLSDKKQQYGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFHIDLSLLD
Protein: Neurofilament heavy polypeptide (NF-H) (200 kDa neurofilament protein) (Neurofilament triplet H protein) (P12037)
Organism: Sus scrofa (Pig)
Function: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P19246}. Cell projection, axon {ECO:0000250|UniProtKB:P19246}.
Interaction partners:
- Kinesin-like protein
- Kinesin-like protein
- Kinesin light chain
- Kinesin light chain 3.
- Kinesin-like protein
- Kinesin light chain
- Mitogen-activated protein kinase
- Mitogen-activated protein kinase.
- Mitogen-activated protein kinase.
- Peripherin
Sequence:
MRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLDDEARQRQEAEAAARALARFAQEAEAARVELQKKAQALQEECGYLRRHHQEEAQAEARDALKCDVTSALREIRAQLEGHAVQSTLQQEEWFRVRLDRLSEAAKVNTDAM
Protein: Citrate exporter 1 (Q6C8F0)
Organism: Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Function: Transmembrane transporter that exports citrate across the cell membrane.
Subcellular location: Cell membrane {ECO:0000269|PubMed:32990722}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MFNLNTKSSKEPEVTEVAVDSTPSSPVTRESSPESSPDNSAVDLEKGKKSKFEMHDQTNLLPRSQLFLVFGAMAFCMLVSFMDQNGISVALPDIAKDLNATDTISWAGTSGLIANTVFQVLYGRLSDIFGRKLVFMIVVCTLVCADIGCACAQTSTQLYIFRAFSGIANGGMSCLTMIVVSDIVTLKERGKYQGILGACVGLGNTIGPFLGAAFTENVSWRAIFYLLAPMGGLCAVVIFFILPSKKPQGSAIQKAKAIDYPGLFCSSVALVFLLVPIAGGGSYYEWDSPMVISMLCIGGVFFIAFFVIEGFFAKLPMMPLRIFGTKALFALMMHSVLLGIAYYGDLYYLPMYMRNIRGWSSMKAAGMSCALVTTQAVTTVISGQYLSRMGRYLEVIYFGFGIWTVGAIMKCFWKRDSNMALLIFSLLFEGAGVGCCFQPTLVAAQALSRKEDRSVVISSRNFLRSFGGAVGLAVCSAILANSLKADLKTKNLPSELYELIVKAPFSLPDLSHYPEYRDQVLDAYMNGSHTVFVFLCPIVGACLLVTVFVKDHGLQTHEKKAAEAKTVEDKDKDESGTDCEDMTKGEVLVSEKEGKLSRNSSSQSMHFGDHTAVNTPAPTGYNTPVVGTLCHNSPNFPPMDHNDVITPLEDFDESPLPPHSPNSSGKRVTIQEE
Protein: Uncharacterized protein C17C9.15c (Q10486)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MSDSFHYQYDRASPERLKPTIYSWTRLRQSTRAQNENEQAKRRQGILEHKRGGSMEMNKFIDESAYMEWEKQLENASEDYAIEPSDLEEEVDQL
Protein: histidine kinase (EC 2.7.13.3) (Q76GZ9)
Organism: Zea mays (Maize)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MVPNGAGECGGGCRRGKAAHAGVGAVAGFFLCLLMVWAVGGSERSGCGRVAEHHGVVRVGQFNLSRSQLQALVFLLSSTQKECMVNSGMVHDGNQVNGAPFIPDIRCIRDRIYDGKQNWLKDAILQESCTAQDKYGLNSHAPAVLEDKLLQNVIQEDINSTTQCNPHECDLCTGISGVNVVQNIGSSSNRTIILCLSAFLGSIVISIVKTTHKRGIQTHKLYADEKVLQAPSTKISRKWSKRALLIGVLFGLCSSLCIFSCMYADVVARRIENLANMCDERARMLQDQFNVSMNHVHALAILVSSFHHGKDPSAIDQKTFEDFTARTTFERPLMSGVAYALKVLHNERQQFEEQHGWKIKKMEDGDQSLVHDYNLEKLEPSPVQDEYAPVIFSQETVKHIISVDMMSGKEDHDNILRSRSTGKGALTSPFKLLKSNHLGVVLTFTVYKYDLPPNATPQERIHATLGYLGASFDVPSLVDKLLEQLASKRKIVVNLYDTTNHTSPIEMYGSDFTPSGDLHISSIDFGDPTRKHEMHCRFKHEPSLPWSAIIISTAVAIIVLLVGHIIYATLNSLEKAEHDYRVMRELKGQAEAADVAKSQFLATVSHEIRTPMNGVLGMLQMLMDTELDTTQQDFVVTAQESGKVLINLINEVLDLAKIESGRIELEAVPFDVRDILDNVISLFYEKSQAKGIELAVLVSDQVPDVLIGDPWRFRQIITNLVGNSMKFTEQGHIFVQVHLVKELSRKGNNFCDVSAHNREILYDSDNSMLWNTLSGLEVADSWRSLENFTMFKNSNGETDTIRLAVRVEDTGIGITKDAQMRIFTPFMQADSSTSRTYGGTGIGLSITKRLVELMGGEIGFTSKSGVGSTFSFTAIFKENRGCPGDMKRYYSEPTPLDFQGMRALIIDGRSARAEVTMYHLRRLGIQCSLVATSESESASSALMKACTSSKNNPDMVLVDTEAWGKGSGLAFYHRFVDCQLKGAHKFSQPMPKTILLGSSISPVESDYLRLTGFGDCIRKPLRLSTIVACLRKTLGVGVTRQQSRDQSLVLQSVLTGKQILVVDDNAVNRKVAAGSLKKYGSTVTCVDSGSDAIDMLKPPHTFDACFMDVQMPEMDGFEATRLIRSIEKKINDMIMMGEISANNYGNKAHWHVPILAMTADVIQATFEKCMQCGMDGYVSKPFEEQQLYSAVAHFLETDEIE
Protein: Mllt6 protein (Q8CFR8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGTVNPLLTQAESSHTEPDLEDCSFRCHGTSPQESLSSMSPISSLPALFDQTSAPCAGGQLDSTAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQVLNVQLSVPFPALPAALPATNGPIPGPYGLLPQAGSSDSLSVSKSPPGKNSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGATGLGAMPMAEGLLGGLAGSGSLPLNGLLGGLNGAAAPNPAGLSQAGGAPTL
Protein: Minicollagen-15 (A6N8P1)
Organism: Hydra vulgaris (Hydra) (Hydra attenuata)
Interaction partners:
Sequence:
MGFKNVAVAVFLFMLVNVYSRKIERRSAPGDKKNEAAAGKRQMCSYSCTPSMPCLPPPGCAPPPPPAMPCGGFAQMPCAPPPPPPQMIPMPVAMPAPCSPQMCGSQMPVGCSPQMCGQSYGQQMGGCGGGGYGGAQGGYGGSQPSYQVAYVQGPQGPMGPAGMPGAPGLPGPMGPSGPPGPCGPPGMPAPATRPCSPICLHWMAIISQAPGAQAQAQPVSCPQQCQQSQCCYPPMQAPMQAPVQAAPACMASCAPQCCGR
Protein: Voltage-gated inwardly rectifying potassium channel KCNH2 (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (gp-erg) (Potassium voltage-gated channel subfamily H member 2) (Voltage-gated potassium channel subunit Kv11.1) (O08703)
Organism: Cavia porcellus (Guinea pig)
Function: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q12809}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Potassium voltage-gated channel subfamily E member 2
- Potassium voltage-gated channel subfamily E member 1
- Potassium voltage-gated channel subfamily KQT member 1
- Sodium channel protein
- Potassium voltage-gated channel subfamily E regulatory subunit 3
- Potassium voltage-gated channel subfamily H member 6
- Amine oxidase
Sequence:
RKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPARDTNHRGPPTSWLTPGRAKTFRLKLPALLALTTRESSSVRPGGTGGSGAPGAVVVDVDLTPAAPSSESLALDEVSALDNHVAGPAEERRALVAPGSPPSSVPGPPHTSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGALPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKEPEEDAQTADCGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPDMNSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFNRQRRRKLSFRRRTDKDPEQPGEVPALGPARVGAGPSSWGRPGTPWGDSPSSGPSSPESSEDEGQGRSSSPLRLVPFSSPRPPGEPRGAETLTEDGDKSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPAPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPASTSPLLPISPIPTLTLDSLSQVSQFVAFEELPPGAPELPQDGPTRRLSLPGQLGALTSQPLHRHGSDPGSAVWDWLILLLVIYTAVFTPYSAAFLLKEPEEDAQTADCGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWY
Protein: GM04789p (Q8MT86)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLINVCRVCGRSRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMIFRRQCILQQKKWVPLLQSDKVGASEEKKVEPNDPSTKMKTTKRRRGRPRMPLEIVDIVVTNDSKASAGESVGCDEFDQPVEISNEPDATDSDVNLEEIDLPDEDGLDSDHDLPNVQIHKCDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFLVASELKAHNLTHHTLEPPFACRYCDRRYFSVVGRKKHERVHTNERPFVCDQCGKAFTRTCILKAHMAVHQVVRKYSCDVCDRSFSLKKHLATHFISNTHKRNAEAVTSSSEYMSMLSFESDETWSQGTPLTTSIDEDLVQSQFDFLCQEV
Protein: Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) (Q9WV27)
Organism: Mus musculus (Mouse)
Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit beta-1
- Sodium/potassium-transporting ATPase subunit gamma
- Sodium/potassium-transporting ATPase subunit beta-3
- Protein ATP1B4
- Sodium/potassium-transporting ATPase subunit beta-2
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 1
- Phospholemman
- Sodium/potassium-transporting ATPase subunit alpha-3
- cAMP-dependent protein kinase catalytic subunit beta
Sequence:
MEPGKEKEVEAPGELNQKPRPSTRSSTTNRQPKMKRRKKDLEELKKEVVMDDHKLTLDELSAKYSVDLTKGLSILEAQDILFQNGPNVLTPPPTTPEWVKFCRQLFGGFSLLLWTGACLCFLAYGIHVNYYKENANKDNLYLGIVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRDGEKMQINVRDVVLGDLVEVKGGDQIPADIRVISAQGCKVDNSSLTGESEPQSRCPDCTHENPLETRNIIFFSTNCVEGTARGIVIATGDYTVMGRIASLTSGLQMGKTPIATEIEHFIHLITAVAVFLGVSFFWLSIILGYTWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTVYEADTSEEQTTGKTFPKSSDTWFYLARIAGLCNRADFKPHQESVPIAKRATTGDASESALLKFIEQSYNPVSEMRQKNPKVAEIPFNSTNKYQMSIHLLEDNSEAHVLLMKGAPERIFDFCSSFLLNGQEYPMDEEMKMDFQNAYIELGGLGERVLGFCFLNLPSNFSKGFQFNTDELNFPMENLCFAGLISMIDPPRTAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNDTAEDIAARLNIPISQVNNKSVKAIVVHGSELKDMESQQLDDILKSYKEIVFARTSPQQKLIIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIILSIPLPLGTITILCIDLGTDMVPAISLAYESPESDIMKRLPRNPKTDNLVNNRLIGMAYGQIGMIQALAGFFTYFVILAENGFKPLDLLGIRLYWDDTQLNDLEDSYGQQWTYEQRKVVEFTCQTAFFISIVIVQWADLIICKTRRNSLFKQGMKNKILIFGLLEETVLAAFLSYVPGMDVSLRMYPLKINWWFCALPYSVLIFVYDEIRKLIIRRRPGGWLEKETYY
Protein: Secoisolariciresinol dehydrogenase (PhSDH) (EC 1.1.1.331) (A3F5F0)
Organism: Sinopodophyllum hexandrum (Himalayan may apple) (Podophyllum hexandrum)
Function: Oxidoreductase involved in lignan biosynthesis. Also involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family. Catalyzes the stereospecific conversion of (-)-secoisolariciresinol to (-)-matairesinol via a lactol intermediate.
Interaction partners:
Sequence:
MGSTSTPASSTNRLQDKVAIITGGAGGIGETTAKLFVRYGAKVVIADISDDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGQHGIRVNCVSPYVVASPLLTDVFGVDSSRVEELAHQAANLKGILLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYTRTNPAFPTALKHGLA
Protein: Large ribosomal subunit protein eL28z (60S ribosomal protein L28-1) (Protein ASYMMETRIC LEAVES1/2 ENHANCER 5) (O82204)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the large ribosomal subunit (By similarity). Essential in leaf polarity establishment, probably having a role for translation in leaf dorsoventral patterning to specify leaf adaxial identity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18305007}. Nucleus {ECO:0000269|PubMed:18305007}. Nucleus, nucleolus {ECO:0000269|PubMed:18305007}. Nucleus, nucleoplasm {ECO:0000269|PubMed:18305007}.
Interaction partners:
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein uL18z
- Large ribosomal subunit protein uL6z/uL6y
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein eL24y
- Large ribosomal subunit protein uL4y
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein eL39z/eL39x
- Large ribosomal subunit protein eL21x/eL21w
Sequence:
MATVPGQLIWEIVKNNNCFLVKQFGRGNSKVQFSKETNNLTNVHSYKHSGLANKKTVTIQAADKDQAVVLATTKTKKQNKPKLSVNKSILKKEFPRMSKAVANQVVDNYYRPDLKKAALARLSAISKGLRVAKSGAKQRNRQA
Protein: Immunoglobulin-binding protein 1b (Alpha 4-b protein) (CD79a-binding protein 1b) (Protein alpha-4-b) (Q9QZ29)
Organism: Mus musculus (Mouse)
Function: Associated to surface IgM-receptor; may be involved in signal transduction (By similarity). May be involved in regulation of the catalytic activity of type 2A-related serine/threonine phosphatases.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein kinase mTOR
- Regulatory-associated protein of mTOR
- Target of rapamycin complex subunit LST8
- Proline-rich AKT1 substrate 1
- DEP domain-containing mTOR-interacting protein
- Immunoglobulin-binding protein 1
- Serine/threonine-protein phosphatase 6 catalytic subunit
- Serine/threonine-protein phosphatase 4 catalytic subunit
Sequence:
MASFTEEMQKPKLRELLETGIQLLEEVEAATQPTGSKPIQEKVREALKLLEKASDMLSQLDLFSRNEDWEEIASADLKYLMLPALKGALTLKLVGSSKRLGLLQDAREHFMNFLTQTHSYHVADFQLPWAQSSSMEGNPAATSDAQEQNLVAMASQRQTKIQRYKQKKAVEQRLSSLKSAVESGQADDERVREYYLLQLRRWISISLDEIENIEQEIEILRERDSLGETSASRSSPQERPPLKPFVLTRSVAQAQVFGAGYPSLATMTVNDWYEQRQKNEVSPTLQEAEKQAPPSETFTVSEKEEPDLEQKEDEDENALHRMQEWDDWKDTHPRGYGNRQNMG
Protein: 4,5-DOPA dioxygenase extradiol (EC 1.13.11.29) (P24197)
Organism: Escherichia coli (strain K12)
Function: In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23666480}.
Interaction partners:
- Uncharacterized protein YqgA
- Quercetin 2,3-dioxygenase
- Pirin-like protein YhaK
- Protein AaeX
- Uncharacterized protein YbiJ
- Biofilm regulator BssS
Sequence:
MTPLVKDIIMSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVVVSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPALAQRLVELLAPIPVTLDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIMLVASGNVVHNLRTVKWHGDSSPYPWATSFNEYVKANLTWQGPVEQHPLVNYLDHEGGTLSNPTPEHYLPLLYVLGAWDGQEPITIPVEGIEMGSLSMLSVQIG
Protein: SVP1-like protein 2 (Q9P3W2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways.
Subcellular location: Vacuole membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Preautophagosomal structure membrane {ECO:0000269|PubMed:23950735}; Peripheral membrane protein {ECO:0000269|PubMed:23950735}.
Interaction partners:
- Autophagy-related protein 2
- Autophagy protein 5
- Autophagy-related protein 9
- Choline transporter-like protein ctl1
- Ubiquitin-like protein ATG12
- Serine/threonine-protein kinase atg1
- Autophagy protein 16
- Autophagy-related protein 21
- Ubiquitin-like modifier-activating enzyme atg7
- Autophagy protein 13
Sequence:
MSTINTVSLNQDASCMSVALDTGYKIFQINPLKLRAQRQFNDGGLSIVKMLFRSNVLLLVGGGGNPKYAPNKLIVWDDVKERPVKELELNFEIKGICFDGKLLAIATASKLFLYQFGNNLKLQRCLDTQNPKGLCAMVTTVEKTAIVFPSRKVGQLQILFLFKDHMNTSIVPAHDSEISCLGISKTGSKIASSSTNGTLIRIWNSETGEKICEFRRGYQHTAVCQLAFSPDELLLACASKKETLHIFSLHGSPNTIRQLTSEEPYEEASEFKSSTTEPRQTHWKRKLLKLIDSGKRAHWRIQLYQSNPVLLHWLDEMTILICYKDAAYQKLKLTIEESSKSVEHANQHVCFHYDYTLEADGSLC