wanglab/gogpt-training-data huggingface dataset:
Protein: Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3) (O88671)
Organism: Rattus norvegicus (Rat)
Function: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Neurogenic locus notch homolog protein 1
- Notch homolog 4, isoform CRA_b.
- Neurogenic locus notch homolog protein 2
- Neurogenic locus notch homolog protein 3
- Delta-like protein 1
- Delta-like protein 4
- Recombining binding protein suppressor of hairless
Sequence:
MVSLQVSSLPQTLILAFLLPQALPAGVFELQIHSFGPGPGPGTPRSPCNARGPCRLFFRVCLKPGVSQEAAESLCALGAALSTSGPVYTEQPGVPAAALSLPDGLVRVPFLDAWPGTFSLIIETWREQLGERAAGPAWNLLARVAGRRRLAAGAPWARDVQRTGAWELHFSYRARCEPPAVGAACARLCRSRSAPSRCGPGLRPCTPFPDECEAPRESLTVCRAGCSPEHGYCEEPDECHCLEGWTGPLCTVPVSTSSCLNSRVSGPAGTGCLLPGPGPCDGNPCANGGSCSETPGSFECACPRGFYGPRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPAFQGSNCERRVDRCSLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGARRCSCALGFGGRDCRERADPCASRPCAHGGRCYAHFSGLVCACAPGYMGVRCEFAVRPDGADAVPAAPRGLRQADSQRFLLPPALGLLAAAALAGAALLLIHVRRRGPGRDTGTRLLSGTREPSVHTLPDALNNLRLQDGAGDGPTSSADWNHPEDGDSRSIYVIPAPSIYAREA
Protein: Protein ALTERED XYLOGLUCAN 9 (Q9M9N9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the plant cell wall polysaccharide acetylation pathway. Does not directly catalyze O-acetylation of xyloglucan but exhibits weak acetylesterase activity in vitro.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:25681330}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Lung seven transmembrane receptor family protein
- Protein REDUCED WALL ACETYLATION 2
- Xylan O-acetyltransferase 1
Sequence:
MLGAIHLGVLAACFVLFVPMAMAGWHLSRNKMLFFSGALFISLAVCVHLTPYFPSVSDIVASVSSVVVYDHRISCINEVNQIVWDVKPVPNPESVRRNNGSTKLDYFVKNWDWMKSRKVLSCEFQKLDKFDVSDLLNGSWVVVAGDSQARFVALSLLNLVLGSDSKAMDSVRGDLFRRHSDYSIVVKEIGMKLDFVWAPYEKDLDDLVVSYKKMKKYPDVVIMGTGLWHMLHVNNASDFGFRLRQLSSHVESLVPLTPKEQEGGGSVSGRSVHLFWIGMPVLINGMLNTDEKKEKMSDTVWHEYDRSLGESKILRQMGGPLILLDIQSFTWNCGPQCTLDGMHYDSAVYDAAVHVMLNALLIESHQSL
Protein: Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Q4KLL0)
Organism: Rattus norvegicus (Rat)
Function: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00649, ECO:0000255|PROSITE-ProRule:PRU00651}.
Interaction partners:
- Transcription initiation factor IIB
- General transcription factor IIF subunit 1
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit
- General transcription factor IIE subunit 1
- TATA box binding protein
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- Transcription initiation factor IIA subunit 2
- Transcription initiation factor IIE subunit beta
Sequence:
MEDEVVRIAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKEPAISSQNSPEAREESSSSSHVSSRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
Protein: Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1) (AtIREG1) (O80905)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in iron transport and iron homeostasis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein DETOXIFICATION 43
- Serine/Threonine-kinase ATM
- Metal transporter Nramp4
- Metal transporter Nramp1
- Fe
- Metal transporter Nramp3
- Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein
- Ferric reduction oxidase 2
- Fcf2 pre-rRNA processing protein
- Ferric reduction oxidase 7, chloroplastic
Sequence:
MENETELRVVHQEEQQREEGEDESQPQNPPPALRRRFVIYLYVGYFLARWSARTWEFSVALYMIHLWPNSLLLAAIYGAIESGSTAIFGPIVGQWVEGMDYVKVLRLWLLFQNLSYTIAGGAVIKLLLVSDLKSRNLPVFAILIVLTNLAGAIGVLSTLAGTILIERDWAVVMSEGHPPAVLTKMNSVIRGIDLSSKLLSPVITGLIISFVSLKASAITFAAWATITAWVEYWLFISVYSGVPAITRSNERRILRSRTKQVEGRDAPVSVSIVPGTEEGYTGNPPSRTGILVILDRMSKSSFVGAWRIYFNQEVVLPGVSLALLFFTVLSFGTLMTATLQWEGIPTYIIGIGRGISATVGLAATLVYPLMQSRLSTLRTGLWSFWSQWSCLLVCVGSIWVKKDKIASYMLMAGVAASRLGLWMFDLAVIQQMQDLVSESDRCVVGGVQNSLQSALDLMAYLLGIIVSNPKDFWILTLISFSTVSLAGMLYTIHLYRIRNHIFHLEKIPLLNKCIFKLLPSRGNV
Protein: Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1) (Q9QXT5)
Organism: Mus musculus (Mouse)
Function: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:14592969, ECO:0000269|PubMed:15162510}.
Interaction partners:
- Roundabout homolog 4
- Neurogenic locus notch homolog protein 4
- Claudin-5
Sequence:
MWGSGELLVAWFLVLAADGTTEHVYRPSRRVCTVGISGGSISETFVQRVYQPYLTTCDGHRACSTYRTIYRTAYRRSPGVTPARPRYACCPGWKRTSGLPGACGAAICQPPCGNGGSCIRPGHCRCPVGWQGDTCQTDVDECSTGEASCPQRCVNTVGSYWCQGWEGQSPSADGTRCLSKEGPSPVAPNPTAGVDSMAREEVYRLQARVDVLEQKLQLVLAPLHSLASRSTEHGLQDPGSLLAHSFQQLDRIDSLSEQVSFLEEHLGSCSCKKDL
Protein: [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B (EC 2.1.1.361) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (A5D6U3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEGSYRMSVRELCETDDLATSLVLDPLLGFSTHKMNISTPPEIRRWGYLRETLLRFKRTHDFQATFDALLDGEWVSDYFAGLGSHRQELLKQHMYRYMTAFLLESGVNIEPCNRYSSETNGAKITSTRHWLVGERVEVLQGCIAELSPEDSAVLRAGVNDFSVMYSTRKRCAQLWLGPAAFINHDCRPNCKFVPGDKNGACVKVVRPISPGEEITCYYGDSFFGEKNEMCECCTCERRGEGSFKKRDQSPDFACTGDPSGQKYEFRETDLRLNRSRGNGTPKPFLAVSNSALPIRNTFSQRTKRNALVLSKMRKTDRRKREEQCKQVEKRMQNLLSSFPHLKLKELSICLHQHSINFLLRCKDPLSKERALLYLIEKERPKSEWITSDSRSAFSPLNNATLNGPEERENEDGEMLNGDSVIQFQPFTLGCVSIVHEKDKMKAKGHNTDASSVRIIHQGISSRTRNILCGRLSSLRAKSRPKLSRFKRRRTRLIKSNSKLSKVRNECSGAQTKDGKWQKERRV
Protein: Protein SLFN14 [Cleaved into: C-terminally truncated SLFN14 endoribonuclease (EC 3.1.-.-) (Schlafen family member 14)] (G1SRW8)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Shows no ribosome-associated and endoribonuclease activities.
Subcellular location: [Protein SLFN14]: Nucleus {ECO:0000250|UniProtKB:P0C7P3}.
Interaction partners:
- peptidyl-tRNA hydrolase
Sequence:
MEIPKTGVETLYPEFVVEVGRVTFGEENRKKMTNSCLKRTENLNIIKATCALLNSGGGVIKAEIHDKNYNYQCHGLGHDLETSFQKLLPFGSQKYLDYMQQGHELLIFVKSWNPDVSSLLPLRICSLRSNLYQRDVTSAINLSASSALELLREKQHAAQRGRRRLHPPRASNSNLQEEEDMKMLASEVFKKDRLMYKEKLNFTESTHVEFKRFTTKKVVPRIKEMLPHYVSAFANTQGGYLIIGVDDKSKEVFGCKKEKVNPDLLKKEIENCIEKLPTFHFCHEKPKINFITKILNVYQKDVLYGYVCVVQVEPFCCAVFAEAPDSWVMRDNAATRLTAEDWVLMMLDIPSAPCNLVTDSNAHLKSPASSAFRSPVCPTKVLEFKGALQRHLFPVTQKTIQFKPESFCKKLFSDHKGLEDLMKTQTYPYSQGIVVFSRSWAGDVGLRKEDRVLCDALLIALHSPLVLYTVLIDPSWAGGREYAWNVALHLKRKLQSVGGYPGKVGIIPRLIQLAGTWCGPGDGSVHYPQSYQLATEDDMEDLLQALVVVSLCSRSLLSDQLGCEFFNLLIAEQCEVLSQSLQETRELFIHCFPGTRKTALAIKTLEKIRDLFRCRPKEILYVCESDFLRDFVIHQTACLAVTRKTFMQGEFPKIKHIVMDETENFCSKYGDWYSKARSITHPRVRGAGNEDLHHGILWIFLDPFQVRHSDVNGLPPPPAQFPRKTITNGIHCAQEIAKVMKGAMKRITENPPSNMSPHTLALFREAACGEALGAHALPGVCETKADLTVEQIANYVAERCHGLFQCGYLPKDVAILCRREEDRARYKLALLRAMELTETHSATEVVFSQAAGVQGEHIILDSVHQFSGLHRNIVFGLSPEQRLSEEFHQLCFASKAIKHLYLLYERGQVSENYYK
Protein: Peptidase S1 domain-containing protein (Q9VPN8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Uncharacterized protein, isoform A
- RE65433p
- LP05863p
- Zinc carboxypeptidase A 1
- GH20109p
- Jonah 65Aii
- Jonah 99Fi
- Jonah 25Biii
- Trypsin zeta
- Lipase
Sequence:
MKLITVTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESFIFNEWVQPATLPSREQVHEGETHLYGWGQPKSYIFSGAKTLQTVTTQILNYEECKEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWITNIQSAYYKLF
Protein: Phosphatidylinositol:ceramide inositolphosphotransferase 3 (EC 2.7.8.-) (Inositol-phosphorylceramide synthase 3) (AtIPCS3) (IPC synthase 3) (Protein ERH1-like1) (Sphingolipid synthase 3) (Q56Y01)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the transfer of the phosphorylinositol group from phosphatidylinositol (PI) to phytoceramide, an essential step in sphingolipid biosynthesis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Proline-rich extensin-like protein EPR1
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Late embryogenesis abundant protein 32
- 2S seed storage protein 5
Sequence:
MPVYVDREAPKLWRRIYSEATLEASLLAEKWKLVLAGLVFQYIHGLAAHGVHYLHRPGPTLQDAGFFILPALGQDKAFFSETVFVTIFGSFILWTFHPFVSHSKKICTVLIWCRVFVYLAASQSLRIITFFATQLPGPNYHCREGSKLAKIPPPKNVLEVLLINFPDGVIYGCGDLIFSSHTIFTLVFVRTYQRYGTRRWIKHLAWLMAVIQSILIIASRKHYTVDIVVAWYTVNLVMFYVDSKLPEMAERSSGPSPTPLLPLSTKDSKNKSKEDHQRLLNENNVADDH
Protein: Immunoglobulin heavy constant gamma 3 (A0A1Y7VJN6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
XTTTAPSVYPLVPGCGDTSGSSVTLGCLVKGYFPEPVTVKWNYGALSSGVRTVSSVLQSGFYSLSSLVTVPSSTWPSQTVICNVAHPASKTELIKRIEPRIPKPSTPPGSSCPPGNILGGPSVFIFPPKPKDALMISLTPKVTCVVVDVSEDDPDVHVSWFVDNKEVHTAWTQPREAQYNSTFRVVSALPIQHQDWMRGKEFKCKVNNKALPAPIERTISKPKGRAQTPQVYTIPPPREQMSKKKVSLTCLVTNFFSEAISVEWERNGELEQDYKNTPPILDSDGTYFLYSKLTVDTDSWLQGEIFTCSVVHEALHNHHTQKNLSRSPELELNETCAEAQDGELDGLWTTITIFISLFLLSVCYSASVTLFKVKWIFSSVVQVKQTAIPDYRNMIGQGA
Protein: Rox8, isoform B (Rox8, isoform C) (Q9VCE3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGNDPYAFIEYSNYQAATTALTAMNKRLFLEKEIKVNWATSPGNQPKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEVHGNLVKCFWGKENGGDNSANNLNAAAAAAAASANVAAVAAANAAVAAGAGMPGQMMTQQQIAAATGAAIPGQMMTPQQIAAQYPYAYQQMGYWYPPATYPTTQMQTQYMQQGYYPYAYPTSAQQAGGVPAGYRMVPPNVAWGVPGTVVPGVTAAAASAAAAANGSLAPQMMYSAAMPQYQTQ
Protein: Septum formation protein MAF homologue, putative (Q4GYP5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Septum formation protein MAF homologue, putative
- Eukaryotic translation initiation factor 1A, putative
Sequence:
MHTKRQREGRGEYFYSLFSSSSRDQHQSSFCRPLMVLQHLELLRKKRILLASASPRRLEILKIIGLDVHVCPSGVAEDLPKSEFKCGGDYALCTAKLKAKHIIRQKMEAANSGSGKTQSGSRSRLPFDVLIAADTVSTMPAHEGDGTIDIIEKPSTREEAAATMRRLSGNSHEMWTGVAIAVVCGKNSTDDDGGVGDNCEELIRWFELKVCTTVHFAVLSEAEILAYTSCPDNWAGKAAGYGIQGIAACMIRSIEGDYYNVMGLPLQAVCALFDKLIDEGIISHN
Protein: Uncharacterized protein C20orf202 (A1L168)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKIAEEPSPSLGQTLEWLRKELSEMQIQDQSLLLTLRHLHSVLEELRADSAHWEDARSSGGTSPIRARAGSEGRGCQPVCSRGLAQLLRGEDSRRSSLP
Protein: Actin, putative (Q580C6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RuvB-like helicase
- Actin-like protein 2, putative
- RuvB-like helicase
- Cofilin/actin depolymerizing factor, putative
- Uncharacterized protein
Sequence:
MAVVEIGWNVRAGYVGDTRCARQFPSLHLLEPPAETSFPSVLMAADGAGSESVSSMWTLQSLDAQRDSNMDYLSRIIGDELHCLKEETLTLVVPEVWHERFDVMRALFHSVLESGVATALYCLRPSVAWALSSGKCSTVVLDVGHSHATAAAVLDGYALRGTVASSDVAGKVVTEVLKGMLDSEQLQALEGVARFKTPTVRALAMDDLVGDIKRLACTVRTDASESNKEEGSLVLRAPDGSAITVEGRARVEAYEVLFRSVGGFGSSLGDLVVGCKQRLDPEWQLQFVSHTLCGGTAQAPGFRERLLTEVQQRDSCYFRYEKEGGFHLSRAVDGAWVGASLATDSSSFASLWITRADMEEEGDSVLYRKLFY
Protein: Myosin-13 (Myosin heavy chain 13) (Myosin heavy chain, skeletal muscle, extraocular) (MyHC-EO) (Myosin heavy chain, skeletal muscle, laryngeal) (MyHC-IIL) (Superfast myosin) (Q9UKX3)
Organism: Homo sapiens (Human)
Function: Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles.
Subcellular location: Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Interaction partners:
- Myosin light chain 1/3, skeletal muscle isoform
- Myosin-1
- Myosin-2
- Myosin-8
- Myosin-10
- Myosin-14
- Myosin-9
- Myosin-6
- Myosin-7
- Myosin regulatory light chain 11
Sequence:
MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE
Protein: Zyxin (Q04584)
Organism: Gallus gallus (Chicken)
Function: Adhesion plaque protein. Binds alpha-actinin and the CRP protein. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1 (By similarity). {ECO:0000250}.
Interaction partners:
- Vinculin
- Talin-1
- Talin 2.
- WH1 domain-containing protein.
- JAC
- Cysteine and glycine-rich protein 1
- LIM and SH3 domain protein 1
- Actin, cytoplasmic 1
- Proto-oncogene tyrosine-protein kinase Src
- Profilin
Sequence:
MASPGTPGTRMTTTVSINISTPSFYNPQKKFAPVVAPKPKVNPFKTGGTSESSQPQPPGTGAQRAQIGRVGEIPVSVTAEELPLPPPPPPGEELSFSSNCAFPPPPPPFEEPFPPAPDEAFPSPPPPPPPMFDEGPALQIPPGSTGSVEKPLAPKAHVEISSAPRDPTPPFPSKFTPKPSGTLSSKPPGLDSTPAPAPWAAPQQRKEPLASVPPPPSLPSQPTAKFTPPPVASSPGSKPGATVPMAPSNSTRYPTSLQTQFTAPSPSGPLSRPQPPNFTYAQQWERPQVQEKPVPTEKSAAVKDMRRPTADPPKGNSPLTMKEVEELELLTQKLMKDMDHPPPVEAATSELCGFCRKPLSRTQPAVRALDCLFHVECFTCFKCEKQLQGQQFYNVDEKPFCEDCYAGTLEKCSVCKQTITDRMLKATGNSYHPQCFTCVMCHTPLEGASFIVDQANQPHCVDDYHRKYAPRCSVCSEPIMPEPGKDETVRVVALEKNFHMKCYKCEDCGRPLSIEADENGCFPLDGHVLCMKCHTVRAKTAC
Protein: Uncharacterized protein Rv2067c (P9WLL9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Beta-lactamase
- Methyltransferase domain-containing protein
- Tat
- Probable conserved transmembrane protein
- ESX-2 secretion system protein eccD2
Sequence:
MTDDHPRADIVSRQYHRWLYPHPIADLEAWTTANWEWFDPVHSHRILWPDREYRPDLDILIAGCGTNQAAIFAFTNRAAKVVAIDISRPALDHQQYLKDKHGLANLELHLLPIEELATLGRDFDLVVSTGVLHHLADPRAGMKELAHCLRRDGVVAAMLYGKYGRIGVELLGSVFRDLGLGQDDASIKLAKEAISLLPTYHPLRNYLTKARDLLSDSALVDTFLHGRQRSYTVEECVDLVTSAGLVFQGWFHKAPYYPHDFFVPNSEFYAAVNTLPEVKAWSVMERLETLNATHLFMACRRDRPKEQYTIDFSTVAALDYVPLMRTRCGVSGTDMFWPGWRMAPSPAQLAFLQQVDGRRTIREIAGCVARTGEPSGGSLADLEEFGRKLFQSLWRLDFVAVALPASG
Protein: LysM domain-containing protein (O07218)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MTPVRPPHTPDPLNLRGPLDGPRWRRAEPAQSRRPGRSRPGGAPLRYHRTGVGMSRTGHGSRPVPPATTVGLALLAAAITLWLGLVAQFGQMITGGSADGSADSTGRVPDRLAVVRVETGESLYDVAVRVAPNAPTRQVADRIRELNGLQTPALAVGQTLIAPVG
Protein: DNA topoisomerase 2-binding protein 1 isoform X1 (DNA topoisomerase II-binding protein 1) (F1R135)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSKASKDAYIVKFVESNGQKSDVALQAYKAIVELQSEKYVQMVDEEAALELDHNDKSLFVFSDFTSSAFDHCRRLGCRIVSPLVVLFCLQKQRCVPKAEQPVYNMSMADVTVSCTNLDKEARSEVMDLIQLMGGRVYRDLNVSVTHLVAGEVGSKKYLVAASLGKPILLPSWVKACWEKSQDSVFHHSELNTEDYRCPVLKGCTVCVTGLSTVERKEVQRLCDQNGATYTGQLKMNECTHLIVNEPTGQKYEFARKWNVYCVSLHWLFDSIEKGFCQDESRYAVERGDKRKTDDKSGRPNTSTPTGQSRSKEDGPSLLGLSHISNISLNVNETALTTAGISHIEMPDPVDSFDITVCRVDDLLDGCKLYLCGLSGKKLEKLRRMVNTAGGLRFNQPTQELTHIVMGEADQGIKAFLDNATHRPHIVTVQWLLESFSRGSLLPENGYFHPSFLPPAPAAVDIPALHKAAPRASRPSVAPPPAPSPARQSRAEEDLLSQYMGNDQTVVELPQDTSSRHSVLHPEPLVEGKDSTLAEASEGGLFFGKRFILVGFGAEAEAQLSELVMENAGKILVGRSRAVAHYAIVPLLGCDVEATVDEVATDTWLAMCVEQQCVLPLASHPLFTPVAVREGFSPLKDCVLSVSQFTGAERDSLIQLAKHLGASVQDYFVRTANQRKGMLASTHLVLQTPEGTKYQAAQKWGLPAVTIRWVLESARTGKRADEGQYLVDLPPSPERTEDSFVGASQKDPPPLRLHQRSPELPLLGPQNSDAITPLDTARFQSRSVRSAVRKLKQGEEEQAEVTTPGQEEAKGAQQKDSSLHLDTPSRFLSRDKLFGPSFNTKDVFDHLQTPGNKSQQGQGAETPLSEVIERNLKAAVANSNRSHVTNLAAMTASPQLGKEPEPEVEQKAAAPLSGVVVCVSKKLSKKQSELNAVAASLGAEFRWSCDDSVTHYIYQGKVGDNSKEYRAVKERGLYIVSQHWLQACADEQKHVSESLYPFTFNPKMSLTMSQMADSTQRSPPSATPRTRLRAFAENEETRLGPDDDITDVSTPKQGSVGEPEKDQTISTEKKNLTETLEMRESLQRQLQEIMSATKLTSGRRGSSRLAKTGPGGLDSPHTPDSLGRMSRRSRNLEAIRMSRQVCVDLNTEPSQSEQIVWDDPTAREERAKLADNLQWPGSPSQHSEPLALVPPPHSDHTTNGRDSMTDSELVEMAAFEVIDAQLKPKGTSSRVDTLHNPKTPEAPSIAFPISKTAALPLPRIEDEEEELKKDPPRFLLSSLNPQERIDYSHLIEELGGVVLEKQSFDPSCTHVIVGHPLRNEKYLAAMAAGKWILHRSYLEACRAEGHFIQEDQYEWGSSSILEALPSINSQQKRLALAAMRWRKTLQGCSNKEGAFGGWIVMLNIDQAREAGFRRLLQSGGAKVLPDPSPSLFKETTHLFVDFSRLKPGDVRVDISEASAHGVKCLKPEYIADYLMQEPSPSMDAYYLPGAAADETEKVVDASSRKRKASGDMSTLKKSRMR
Protein: Melanoma-associated antigen C1 (Cancer/testis antigen 7.1) (CT7.1) (MAGE-C1 antigen) (O60732)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31429579}.
Interaction partners:
- Cancer/testis antigen 1
- Dermatan-sulfate epimerase
- U4/U6.U5 tri-snRNP-associated protein 1
- Melanoma-associated antigen C2
- X antigen family member 1
- Cancer/testis antigen 2
Sequence:
MGDKDMPTAGMPSLLQSSSESPQSCPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEGEDSSDPLQRPPEGKDSQSPLQIPQSSPEGDDTQSPLQNSQSSPEGKDSLSPLEISQSPPEGEDVQSPLQNPASSFFSSALLSIFQSSPESTQSPFEGFPQSVLQIPVSAASSSTLVSIFQSSPESTQSPFEGFPQSPLQIPVSRSFSSTLLSIFQSSPERTQSTFEGFAQSPLQIPVSPSSSSTLLSLFQSFSERTQSTFEGFAQSSLQIPVSPSFSSTLVSLFQSSPERTQSTFEGFPQSPLQIPVSSSSSSTLLSLFQSSPERTHSTFEGFPQSLLQIPMTSSFSSTLLSIFQSSPESAQSTFEGFPQSPLQIPGSPSFSSTLLSLFQSSPERTHSTFEGFPQSPLQIPMTSSFSSTLLSILQSSPESAQSAFEGFPQSPLQIPVSSSFSYTLLSLFQSSPERTHSTFEGFPQSPLQIPVSSSSSSSTLLSLFQSSPECTQSTFEGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSPHYFPQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGEEFQSSLQSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPESAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPLQSPVISFSSSTSLSPFSEESSSPVDEYTSSSDTLLESDSLTDSESLIESEPLFTYTLDEKVDELARFLLLKYQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDPDDSYVFVNTLDLTSEGCLSDEQGMSQNRLLILILSIIFIKGTYASEEVIWDVLSGIGVRAGREHFAFGEPRELLTKVWVQEHYLEYREVPNSSPPRYEFLWGPRAHSEVIKRKVVEFLAMLKNTVPITFPSSYKDALKDVEERAQAIIDTTDDSTATESASSSVMSPSFSSE
Protein: Forkhead box F2b (Forkhead box protein F2) (E7FER3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
Sequence:
MRDACIITGFQLKRGVYPQLFFLKSRYWLSIDPLGFALPFSSDNGLFSYVTAGPMTTESSHGPLGSTPPTRTSPATTALHPGLMNSTGNLEEHSAVSKSKKTNSGLRRPEKPPYSYIALIVMAIQSAPTKRLTLSEIYQFLQTRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPTSEFMFEEGSFRRRPRGFRRKCQAMKPMYRMMNGLGFGSAILPQSFDYQSPTGALACHSSGYNLDLSGSGYESISSGHHGHMSPSSRHGYMSSCPMPGNGDYAVESNTSPVPSSPAVAGALEGHSPYSESTALWASSNSSYLKQANTITSNSQPTGQHPGIFTYSLEQGYIQQSARDNADMSVGLSRYPTHSSPVGERKDFMLNFNGITSFHPSAGGYYHHHHHHHHHQSMHQDVKPCVM
Protein: Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I] (Q00623)
Organism: Mus musculus (Mouse)
Function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
Subcellular location: Secreted.
Interaction partners:
- Phospholipid-transporting ATPase ABCA1
- Apolipoprotein B-100
- Apolipoprotein E
- Scavenger receptor class B member 1
- Apolipoprotein C-III
- Apolipoprotein A-II
- Phosphatidylcholine-sterol acyltransferase
- Clusterin
- Apolipoprotein C-I
- Serum paraoxonase/arylesterase 1
Sequence:
MKAVVLAVALVFLTGSQAWHVWQQDEPQSQWDKVKDFANVYVDAVKDSGRDYVSQFESSSLGQQLNLNLLENWDTLGSTVSQLQERLGPLTRDFWDNLEKETDWVRQEMNKDLEEVKQKVQPYLDEFQKKWKEDVELYRQKVAPLGAELQESARQKLQELQGRLSPVAEEFRDRMRTHVDSLRTQLAPHSEQMRESLAQRLAELKSNPTLNEYHTRAKTHLKTLGEKARPALEDLRHSLMPMLETLKTQVQSVIDKASETLTAQ
Protein: Golgi complex-localized glycoprotein 1, isoform B (M9PIG4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MLHVLFSVLLMATANTAADTLQRSRRVAIDVDNAKDMHSIIDLAECQDLKKLCAHHKSTDNLSMLECALTFSSSQLMDLPEGCQNALWMQQRQLQLPAWLESTFLPAYCPAERPKLESCLNAVHLWSCLEQQRLKLLQNNACHQHLRRAYESLGQDYSAVDEFYTACGPLVEENKCGRLNVDHLPSVLSQLTTVQCLQESATKTGIEPVCQAAINSIELFRVCQEDFSSFCSQEKSGTAAGYKCLVRHKNHPSMSSQCSARITLRDQQIGRDYRVSHGLAKACKDDIKLYHCRRGVSEDKHVRLAQILLCLESVSKNGTKLAPPCLTELTDHRRMLMTDYQLSPELLNDCADDIPKFCPDEHKAQLVNGMTSTGGEIIHCLLEHVKARRPQRRVTAQCQRGLETLIKASDAGEDWRVDPVLRRACKPVVDVVCRDVQGGEARVMGCLMEHIGTPVMLPDCEQALLIIEYFVARDFKLDPQLYKHCRDDAVKYCRAKKQWDDAQNIQMDPERGPMILPCLHRMAFSEDEHQTLRKDCFQEVKRVMRQRAISMDLIPEVEDYCLNDLSAFCADCTEKGSEMECLQKNMDQLQPECKTVVVKYTEEEAAHVELNPVIMNVCGEAMQQHCSAILKSGKDNGDMMDCLIAHKNDADLRKDLRCRAAIEHFQIISLKSFHFTTKFKEACRPYVQRFCSSSATKNEVVACLSEVMRNDTIKAQRHQIPKECRHQVKAQLYQQRESIQLDPKLANACKRELEQFCEEEKGPGQVNEKALECLIRKTHSLGKPCHHAIFMVKKSELGDSGTDYTLLTTCKEMIYKFCPSTDSSKLLDCLKTYKDDTQFDQRCHLVVVNRMIEQNTDFRFNPSLQSACGKNIDRYCSNIVASALPNEELNGKVIHCLKDKFRQSALDEPCAKEMIKILQEQALNYKLNPLLQVFCKSEIQELCKANVDSDEHGQLAECLKTAFLQKQIINRQCQMEVATLIAEAKADIHVDPILETACTVDLLRYCSKVAAGNGRKLNCLRTLLKDTPNSLEADCREKLQRRIEMFRNADDTLALPPEDVQQLVQQVVASPARKFFLVILMSATGLVFLTGIFLGRATKRAMGLKNK