wanglab/gogpt-training-data huggingface dataset:
Protein: G patch domain-containing protein 11 (Coiled-coil domain-containing protein 75) (Q8N954)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}.
Interaction partners:
- Splicing factor 45
- U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
- Splicing factor 3A subunit 3
- U2 small nuclear ribonucleoprotein A'
Sequence:
MRSARSTALNRGEQRAVRYYSHMKLNMAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD
Protein: Chromosome segregation in meiosis protein 4 (Q08955)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in chromosome segregation during meiosis. Involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12514182}; Single-pass membrane protein {ECO:0000269|PubMed:12514182}. Nucleus membrane {ECO:0000305|PubMed:12514182}; Single-pass membrane protein {ECO:0000305|PubMed:12514182}.
Interaction partners:
- Spindle pole body assembly component MPS3
- Non-disjunction protein 1
- Monopolar spindle protein 2
- Myosin-2
- Actin
- ISWI chromatin-remodeling complex ATPase ISW2
- Meiosis-specific protein HOP1
Sequence:
MMDGSITRKVTSTLSNQLATWKWKLQLSLLERKLATINNDYFLLQWELLFITNEVMKWKEMIAFLESQLFCTTQNFVAQETHDRETFQSLVDDYNKQLSENNLIISVLKSRPQLSSFPIYLSDEVCSHLKFVIAELNSLIIVFFISLVFLWVSIEV
Protein: Uncharacterized protein YcbK (P0AB06)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Hydroxyacylglutathione hydrolase GloC
- Probable L,D-transpeptidase YcbB
- Uncharacterized ferredoxin-like protein YdhX
- Penicillin-insensitive murein endopeptidase
Sequence:
MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNNLHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTRKPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRAGGVGYYPRSNFVHIDTGPARHW
Protein: Protein ADMETOS (Q9SZ59)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Product of a dosage-sensitive gene that contributes to the maintenance of paternally and maternally imprinted gene expression in the endosperm in order to balance parental contributions. Underlies postzygotic reproductive isolation by promoting triploid seed arrest in a genetic dosage-dependent manner, thus being a component of postzygotic interploidy hybridization barriers.
Interaction partners:
- Nuclear transcription factor Y subunit C-7
- Alpha/beta-Hydrolases superfamily protein
- Uncharacterized protein
- Uncharacterized protein
- F-box/kelch-repeat protein At5g03020
- Transport/golgi organization-like protein, putative
- Coatomer subunit zeta-1
- non-specific serine/threonine protein kinase
- Uncharacterized protein
- F-box protein At1g11810
Sequence:
MFSGEGASQIRIAPEDKPIQWCYQILKSRDFKSARYITQMNLKLSKTRHDEYEKGLAICDILIAAENRLPNGLLDCYGMIRMTRPGLVLYQNIEKELNLLGWGNISNPFPFRQEASEKFFFAWSLLSNPTIKEMYDYATSDEVNLEPQGNVNEYMDVDSSSQSGYGLGSVLCSDLPGSEYLKEFADVYPLPLAEKGQAPHNRFGWYDHNVGPETNNNVVVTYEDAKEEECDMSSSSELRIINGRRVKITIEEAAETSDTPSCSR
Protein: Uncharacterized protein (Q384P8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRRPLSFIGKASGLLHCPNNLQAIVPALCISTRSVASYPSPGTDRGKVKINRKKYNFLNSERLMKTNKEPRSRREVRIRDDVFFHRRIQYRQAIGTNVEKHIRYLPDNVKQYVFFKNKVNSLVSTGFHGARKAPGIVARRIVLMVENEILKPENRDHLVELIESVGVEPPTKEEWDRYTNKKTGRISINLYYHANVEKHLRQFFTAKVGGSFRLFQAFMVLKRNDFSVCPPMYEWALRQGPIRNEELVERSEVKEQRDVIGELAKFQRPHIDRAFKKLTNQAKQKCLKEAEDNEDQLRREYEQERVFAAKVLSGVAALKEVRAMTSPALTYYRHEHYKYVIKKNGSVDATLRRSRDESPSWHMIPKEEQVKFYCFERTMEMHPVGGAHLFIRYACRDYGLTREEAMLRWSFLSDLQKAALSFCFYAPISASNHSGVAFRRFYWKQCYVHGLMMTGKACGNRAFFERMRKVWMGMSADERAQYEETDSFSSVFPLHRQSASSVERDGTVSASESKVSDSIFSMQSSSRACSTVNGTNRATPTLERNGSTPTDEEDDKELLYFEDEVIEGDDEDDKSGGDSHRVNGGPTATRRCEEVRAVEPYIEEAVAFSI
Protein: Histidine/lysine/arginine/ornithine transport system permease protein HisQ (P52094)
Organism: Escherichia coli (strain K12)
Function: Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity).
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Histidine/lysine/arginine/ornithine transport system permease protein HisM
- Histidine-binding periplasmic protein
- Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP
- Lysine/arginine/ornithine-binding periplasmic protein
- Putative ABC transporter arginine-binding protein 2
- ABC transporter arginine-binding protein 1
- Glutamine-binding periplasmic protein
- L-cystine-binding protein TcyJ
- Arginine transport ATP-binding protein ArtP
- Glutamine transport ATP-binding protein GlnQ
Sequence:
MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRLSGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPSMMRYALPGIGNNWQVILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERRYSVGVKRADL
Protein: Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK (EC 4.2.-.-) (P45202)
Organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Function: Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. Probably compensates for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Does not cleave Pro-tRNA(Pro).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Proline--tRNA ligase
Sequence:
MTPAIDLLKKQKIPFILHTYDHDPNNQHFGDEAAEKLGIDPNRSFKTLLVAENGDQKKLACFVLATANMLNLKKAAKSIGVKKVEMADKDAAQKSTGYLVGGISPLGQKKRVKTVINSTALEFETIYVSGGKRGLSVEIAPQDLAKVLGAEFTDIVDE
Protein: Rho GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Q8RWQ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state.
Interaction partners:
- Rho GTPase-activating protein 1
- Rac-like GTP-binding protein ARAC11
- Ras-related protein RABA4d
Sequence:
MEASLAALERPRGSASNTVFKSGPLFISSKGLGWTSWKKRWFILTRTSLVFFKNDPGTLPQKGGEVNLTLGGIDLNNSGSVVVREDKKLLTVLFPDGRDGRAFTLKAETFEDLYEWKTALEQALAQAPNAALIMGQNGIFRAETNEAIEGREKRPLKSLVVGRPILLALEDIDGSPSFLEKALQFIEKYGTKIEGILRQSADVEEVERRVQEYEQGKTEFTFDEDPHVVGDCIKHVLRELPSSPVSASCCTALLEAYRIESKEARISSLRSAIAETFPEPNRRLLQRILKMMHTISSHSHENRMNPNAVAACMAPLLLRPLLAGECDLEDDFDGGEDNSAQLLAAANAANNAQAIITVLLEDYGSIFDEENIQRCSISTESHIGNSGPDDSSDDDNNMKNGYHNADNEVEPVTDDDNDRALSGKMSESSGCTGSDLYEYKGFVADDSDIESPRDTNGPRCNSNIRTDHLMRNPFVNSTDQQAGEQIGDDPTKYGVNSCLAHVSESYQQSGTGLNVPTHGNTLAAPGLESPSAKSVNKGTPSSVHAKRATFWGRGSARKISTDGSFDSSGEDELAIQRLETTKNELRQRIAKEARGNAILQASLERRKQALHERRLSLEQDVSRLQEQLQAERDLRAALEVGLSMSSGQFSSHGVDSKTRAELEEIALAEADVARLKQKVAELHHQLNQQRQTHFGSFSDARDTHQYLQNHNPQKRFLQQDFDSTLAYVNHERKQRHEENVLGAEWRNSKGAGSFGVGNSRQPSRKQIPESTNTTDSKISEESGKISVDKLSSIDSPSIPSTSRVLDITEYPRLNHPSAAASAALVELTTRLDFFKERRSQLMEQLQNLDLNYGGSSSQDFIHRPSSPPWN
Protein: Toll-like receptor 10 (CD antigen CD290) (Q9BXR5)
Organism: Homo sapiens (Human)
Function: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Toll-like receptor 2
- Toll-like receptor 1
- Myeloid differentiation primary response protein MyD88
- Toll-like receptor 6
- Lymphocyte antigen 96
- Profilin-3
- Profilin-4
- Profilin-1
Sequence:
MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVLATREMYELQTFTELNEESRGSTISLMRTDCL
Protein: RecQ like helicase 5 (J3QLU0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQLRKGKDPKIEEFVPPDENCPLKEASSRRIPRLTVKAREHCLRLLEEALSSNRQSTRTADEADLRAKAVELEHETFRNAKVANLYKASVLKKVADIHRASKDGQPYDMGGSAKSCSAQAEPPEPNEYDIPPASHVYSLKPKRVGAGFPKGSCPFQTATELMETTRIREQAPQPERGGEHEPPSRPCGLL
Protein: Protein DJ-1 homolog A (AtDJ1A) (Q9FPF0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in oxidative stress response. Confers protection against diverse stresses by binding both CSD1 and GPX2 and mediating the cytosolic activation of the Cu-Zn-dependent superoxide dismutase activity of CSD1.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:20406884}. Nucleus {ECO:0000269|PubMed:20406884}.
Interaction partners:
- DJ-1 protein homolog E
- DJ-1 protein homolog F
- Hydroxyacylglutathione hydrolase 2, mitochondrial
- Hydroxyacylglutathione hydrolase 1, mitochondrial
- Probable hydroxyacylglutathione hydrolase 2, chloroplastic
- Persulfide dioxygenase ETHE1 homolog, mitochondrial
- Hydroxyacylglutathione hydrolase cytoplasmic
- AAA-ATPase At3g28510
- Superoxide dismutase 1
- Probable glutathione peroxidase 2
Sequence:
MASFTKTVLIPIAHGTEPLEAVAMITVLRRGGADVTVASVETQVGVDACHGIKMVADTLLSDITDSVFDLIVLPGGLPGGETLKNCKSLENMVKKQDSDGRLNAAICCAPALALGTWGLLEGKKATGYPVFMEKLAATCATAVESRVQIDGRIVTSRGPGTTIEFSITLIEQLFGKEKADEVSSILLLRPNPGEEFTFTELNQTNWSFEDTPQILVPIAEESEEIEAIALVDILRRAKANVVIAAVGNSLEVEGSRKAKLVAEVLLDEVAEKSFDLIVLPGGLNGAQRFASCEKLVNMLRKQAEANKPYGGICASPAYVFEPNGLLKGKKATTHPVVSDKLSDKSHIEHRVVVDGNVITSRAPGTAMEFSLAIVEKFYGREKALQLGKATLV
Protein: RCC1 domain-containing protein 1 (A6NED2)
Organism: Homo sapiens (Human)
Function: Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.
Subcellular location: Chromosome {ECO:0000269|PubMed:24981860}. Note=Colocalizes with trimethylated 'Lys-9' of histone H3 (H3K9me3). {ECO:0000269|PubMed:24981860}.
Interaction partners:
- Bifunctional peptidase and arginyl-hydroxylase JMJD5
Sequence:
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATELNEDGSQVKRTGGAEDGAPAPFIAVQPFPALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAVTCGPWNTYVYAVEKGKS
Protein: Probable serine/threonine-protein kinase PBL15 (EC 2.7.11.1) (PBS1-like protein 15) (Q9SY91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in plant defense signaling.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9ZUF4}.
Interaction partners:
- HSR201-like protein
- Non-specific lipid transfer protein GPI-anchored 5
- Subtilisin-like protease SBT4.12
- Protein indeterminate-domain 6
- Large ribosomal subunit protein uL30w
- Zinc transporter 3
- TRAF-like family protein
Sequence:
MRDSSTTASTKSSPLWKPFASNCCSVDDQTVFGNLSRCRPSRSEFSKNHLGPLPSFRRLSFADLSRSSSARINEDLAQTLGADLVDFQMCELKMITQSFSGNYLLGEGGFGKVYKGYVDDYLRQSLKAQPVAVKLLDIEGLQGHREWLSEVIFLGQLKHPNLVKLIGYCCEEEERVLIYEFMPRGSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDLESPIIYRDFKTSNILLDSDFTAKLSDFGLAKMGPEGSKSHVTTRVMGTYGYAAPEYVSTGHLTTKSDVYSYGVVLLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLAGQYSVKAAKDTALLALQCVSPNPKDRPKMLAVVEALESLIHYKDMAVSSGHWPLSPKSQGGKVSPKVRGDHRSGRKSAPGSLRS
Protein: Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2) (P25098)
Organism: Homo sapiens (Human)
Function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity). Inhibits relaxation of airway smooth muscle in response to blue light.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P26817}. Cell membrane {ECO:0000250|UniProtKB:P21146}. Postsynapse {ECO:0000250|UniProtKB:P26817}. Presynapse {ECO:0000250|UniProtKB:P26817}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Beta-arrestin-2
- Beta-arrestin-1
- ARF GTPase-activating protein GIT1
- Guanine nucleotide-binding protein G
- Protein smoothened
- Beta-2 adrenergic receptor
- G protein-coupled receptor kinase 3
- C-X-C chemokine receptor type 2
- Mu-type opioid receptor
Sequence:
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLVQRGSANGL
Protein: Dorsal-ventral patterning tolloid-like protein 1 (EC 3.4.24.-) (Mini fin protein) (O57460)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for patterning ventral tissues of the tail. May increase bone morphogenetic protein (BMP) activity at the end of gastrulation by proteolytic cleavage of chordin and release of BMP from inactive complexes.
Interaction partners:
- Chordin
- Sizzled
- BMP-binding endothelial regulator.
- Bone morphogenetic protein 2
- Twisted gastrulation protein homolog 1-A
- Bone morphogenetic protein 4.
- Bone morphogenetic protein 7
- Mesencephalic astrocyte-derived neurotrophic factor.
Sequence:
MDYLYSALTSKMNWIALLLAGLTFCCKVSVHSCLDYDDSYDYYEEEKTETIDYKDPCKAAVFWGDIALDDEDLKMFHIDGTIDLKQQTHGRQGHTSGGLGEHVPTKKRGSLYLLLDRIRRLGFESWPVNSSKDVSSIKTGIRRVNSARNVKSRVPRAATSRAEKIWPGGVIPYVIGGNFTGSQRAMLKQAMRHWEKQTCVTFIEKTDEESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVTIIRDNIQPGQEYNFIKMEPGDVNSLGEPYDFDSIMHYARNTFSRGMFLDTILPSRDENGVRPAIGQRTRLSKGDISQAKKLYRCPACGETLQDSVGNFSSPGYPNGYPSYTHCVWRISVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKAPLLGRFCGDKIPEVLVSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEISKDSGQIQSPNYPDDYRPSKECVWRITVSEGYSVGLSFQVFEIERHDSCAYDYLEVRDGLSENSPLIGRFCGYDKPEDIRSTSNNLWMKFVSDGTVNKAGFAANFFKEEDECLKPDNGGCEQRCVNTLGSFKCACDPGYELAPDKKSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISMQFEAFELEGNEVCKYDYVEVRSGLSSDSKLHGKYCGTEVPEVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECINTIGSYVCQCRNGFILHENKHDCKEAECEHKIHSTTGTISSPNWPDKYPSRKECTWDITATPGHRVKISFNEFEIEQHQECAYDHLEAFDGDSDKTPILSRLCGNKIPEPLISTGNKMYLRFISDASVQRKGFQATHSTECGGRLKAEARQKNLYSHAQFGDNNYPGHTDCEWLIVAESGYGIELTFTTFEVEEEADCGYDYIELYDGYDTGAHKIGRFCGSGPREELYSAGDAVLIHFHSDDTISKKGFHIRYTSTKFQEALHTRK
Protein: ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme) (A0A060W7T9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
- Succinate--CoA ligase subunit alpha, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Citrate synthase
- Citrate synthase
- Citrate synthase
- Citrate synthase
- Peripheral subunit-binding
- Uncharacterized protein
- Lipoyl-binding domain-containing protein
- 2-oxoacid dehydrogenase acyltransferase catalytic domain-containing protein
Sequence:
MSAKAISEQTGKEFLYKYICTSAAVQNRFRYANVTTETDFDRLAQDHPWLLTERLVVKPDQLIKRRGKLGLVGVNLDLKGVQEWLKTRLMKETMVGKAKGILKNFLIEPFVAHKQEEEFYVCIYATREGDYVLFHHEGGVDVGDVDSKASKLLVGVDEKLTEDAVKKQLLTHVAADIKEVLASFIVGLFNLYQDLYFTYLEINPLVVTKDGVFVLDMAAKIDATADYLCKAKWGDVEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPRGRIWTMVAGGGASVVYSDTICDLGGVDELANYGEYSGAPSEQQTYDYAKTILSLMTREKHPEGKVLIIGGSIANFTNVAATFKGIVRAIRDYQGPIKEHEITIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPKEPPVAAHTANFLLNSSASSSTPASSRTASFSENKAGPGASAAKKAKSGAPPGDQAIFLPLSKCVCTPNLFKASTLFSKQTKSIVWGMQTRAVQGMLDFDYTCSRDEPSVSAMVYPFTGDHKQKFYWGHKEILLPVYKNMGDAMKKHPEVDVLISFASLRSAFDSTMETMQYPQIHTIAIIAEGIPEAQTRKIIKRADEKGITIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSIYTDHVLRYQDTPGVEMIVMLGEIGGTEEYTICQGIKSGRITKPVVSWCIGTCATMFSSEVQFGHAGACANQASETAVAKNLALKEAGAFVPKSFDELGDVIKSVYDDLVGTGVIVPAMEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKSEMGLGGTLGLLWFQRRLPSYAAKFIEMCLMVTADHGPAVSGAHNTIVCARAGKDLISSLTSGLLTIGDRFGGALDAAAKQFSKAFDSGMLPMEFVNKMKKEGNLIMGIGHRVKSINNPDMRVQILKDFVKKNFPSTQLLDYAMDVEKITTAKKPNLILNVDGFIGVAFVDLLRNCGGFTRDEADEFVEIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM
Protein: F-box only protein 40 (Muscle disease-related protein) (Q9UH90)
Organism: Homo sapiens (Human)
Function: Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- S-phase kinase-associated protein 1
- E3 ubiquitin-protein ligase COP1
- Cullin-1
- Astrotactin-2
- Diphosphomevalonate decarboxylase
- Squalene synthase
Sequence:
MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPLEQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETPSEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGGAVGGVDIGLVPHGLSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCESKNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKRARLGDAMLSCKPSEHKAVDTSDLGITVEDLPKSDLIKTTLQCALERELKGHVISESRSIDGLFMDFATQTYNFEPEQFSSGTVLADLTAATPGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVSVLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSMSEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS
Protein: RRM domain-containing protein (Q7Z204)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MNASSAPQQQQQQQQPQQGQAPQQQQQGPPQHQYQQQRPFHGHSMNNPEMLQRMQYPQVYQSYYGYHPAAVYQQHYDVNSLASQMGGMHVGGGNPQANGGGDMYGAHMYGQNAGGQGGQGVGQGGQGGNQQFYNPNNGRNKKYFQPMNPQ
Protein: Formin-like protein 2 (Formin homology 2 domain-containing protein 2) (Q96PY5)
Organism: Homo sapiens (Human)
Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Cell division control protein 42 homolog
- Rho-related GTP-binding protein RhoC
- Profilin-1
Sequence:
MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSNLPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITVLKTVPFTARTAKRGSRFFCEPVLTEEYHY
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic and interferon-induced mortality 19 protein) (GRIM-19) (Gene associated with retinoic and IFN-induced mortality 19 protein) (NADH-ubiquinone oxidoreductase B16.6 subunit) (Q9ERS2)
Organism: Mus musculus (Mouse)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:38575788, ECO:0000305|PubMed:12628925}; Single-pass membrane protein {ECO:0000269|PubMed:38575788, ECO:0000305|PubMed:12628925}; Matrix side {ECO:0000269|PubMed:38575788, ECO:0000305|PubMed:12628925}. Nucleus {ECO:0000269|PubMed:12628925}. Note=Localizes mainly in the mitochondrion. May be translocated into the nucleus upon IFN/RA treatment. {ECO:0000250|UniProtKB:Q9P0J0}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 4
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase 1 alpha subcomplex subunit 7
- NADH dehydrogenase 1 alpha subcomplex subunit 3
- NADH dehydrogenase 1 alpha subcomplex subunit 5
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
Sequence:
MAASKVKQDMPPPGGYGPIDYKRNLPRRGLSGYSMFAVGIGALIFGYWRMMRWNQERRRLLIEDLEARIALMPLFQAEKDRRTLQILRENLEEEAIIMKDVPNWKVGESVFHTTRWVPPLIGEMYGLRTKEEMSNANFGFTWYT
Protein: Mast cell protease 1-like 3 (F1LPL5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQALLFLMALLLPSGAGAEEIVGGVESIPHSRPYMAHLKITTEKGYVTFCGGFLISRQFVLTAAHCNGREITVTLGAHDVSKRESTQQKLKVEKQIIHKNYNFFSNIHDIMLLKLEKQVELTPAVDVVPLPSPSDFIDPGTMCQAAGWGQTGVTDPTSYTYTLREVELRIMDVEACKIFSDYDYNFQMCVGSPGRMRSPYEGDSGGPLLCAGVAHGIVSHGREDAKPPAVFTRISPYVPWINIVLSASS
Protein: Tail protein-depolymerase (A0A1W6JT72)
Organism: Escherichia phage vB_EcoM_ECOO78
Interaction partners:
Sequence:
MELKTYFAQDRNGNLIPSATVSIFLSGTSTLATGLKTVSGANLTNPFTAGSDGKIQFYAPDGIYDMQVSLGSVDGVKVTFQCIDVQQQLSEASSAADRAEAAAESIESQSANIESNSREQWRRSLADAGITLVNGSFEAGATVSNASEAVWHIAGGQCYTWGGVMPKVVTEGSTPSETGGVSPGAWTSVGNKSFSQILASNKGMNLIGDVDSVAQLASVSGASVGDKILVRSYIAGSNKGGGTFVAVENTETPDGVVVFDGVGVKWRRLFFAGEVNVFDAGYTGSGDIAVYINKVNSAGYDCFIPCSGAFSSAIEIDFSKGSVRGANKCTLTEIEGIPGDYALKLFNSNTDYADRDSINANAILDGVAFQFSGTKKIALGGAGTGELSELRISNFGFISSAGLEFLDNSYRIIFDKGAISRSFNDTLIFNSPANSGEVINFNHCWMVDNGGPLKFKNGQFIFNGCSMPAGKKAGYFDPNIILEDNATVVYANGNIEFQPGQSFVAFVVGGSSRLSIKDSTLLTPSGYSAIPIVANDDAVVSLTNCSLPLYEQTEIAAGAAARQIIGGNSKKVMSYGCYPRAGFITANWDKGNIVSAYINSLSNGSGQFSNYSNWSLMQTGSGVVTAGTDTDVPNTIMFSRSLYVTVPSVGATADFYQDCLDCSPGRYFQLGFWAKNAVTSLASIEFFDKEGNSVQGKIPFNIPSVNAWGFYALVDIVPPGASKARVNFAVSGEVGTLHIHNAIYGLI