wanglab/gogpt-training-data huggingface dataset:
Protein: 2-hydroxyacid dehydrogenase homolog 1 (EC 1.1.1.-) (Q9P7P8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Putative phosphoserine aminotransferase
Sequence:
MRIAFFSAQPYEKEPFEKVNENYKHEIDYHESILNKKTAVLAEKAPVVCVFVNDKVDADTLKVLAKNGTKLIALRCAGFNNVDLKAAADNGITVVRVPAYSPYAVAEYTIGLLLSLNRKIHRAYVRVREDDFNLNGLLGHDLHGKTIGLLGTGRIGGLVAKCLKLGFGCEVLAHDIKPNKELEKFGIQFVEQQEVLAKADFLCLHCPLTPDTEHLVDEKLLASMKKGVKIINTSRGGLVDTKALVKAIESGQVGGCAMDVYEGERRLFYRDLSNEVIKDTTFQQLANFPNVLVTSHQAFFTAEALSAIAHTTLKNVSDFASQNNDPSVIVKN
Protein: Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) (Q61824)
Organism: Mus musculus (Mouse)
Function: Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- SH3 and PX domain-containing protein 2A
- Growth factor receptor-bound protein 2
Sequence:
MAERPARRAPPARALLLALAGALLAPRAARGMSLWDQRGTYEVARASLLSKDPGIPGQSIPAKDHPDVLTVQLQLESRDLILSLERNEGLIANGFTETHYLQDGTDVSLTRNHTDHCYYHGHVQGDAASVVSLSTCSGLRGLIMFENKTYSLEPMKNTTDSYKLVPAESMTNIQGLCGSQHNKSNLTMEDVSPGTSQMRARRHKRETLKMTKYVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDIDKCSISQDPFTSLHEFLDWRKIKLLPRKSHDNAQLISGVYFQGTTIGMAPIMSMCTAEQSGGVVMDHSDSPLGAAVTLAHELGHNFGMNHDTLERGCSCRMAAEKGGCIMNPSTGFPFPMVFSSCSRKDLEASLEKGMGMCLFNLPEVKQAFGGRKCGNGYVEEGEECDCGEPEECTNRCCNATTCTLKPDAVCAHGQCCEDCQLKPPGTACRGSSNSCDLPEFCTGTAPHCPANVYLHDGHPCQGVDGYCYNGICQTHEQQCVTLWGPGAKPAPGICFERVNSAGDPYGNCGKDSKSAFAKCELRDAKCGKIQCQGGASRPVIGTNAVSIETNIPQQEGGRILCRGTHVYLGDDMPDPGLVLAGTKCAEGKICLNRRCQNISVFGVHKCAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTVGILVSILCLLAAGFVVYLKRKTLMRLLFTHKKTTMEKLRCVHPSRTPSGPHLGQAHHTPGKGLLMNRAPHFNTPKDRHSLKCQNMDISRPLDARAVPQLQSPQRVLLPLHQTPRAPSGPARPLPASPAVRQAQGIRKPSPPQKPLPADPLSRTSRLTSALVRTPGQQEPGHRPAPIRPAPKHQVPRPSHNAYIK
Protein: Gram-negative bacteria-binding protein 1 (Q9NHB0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a key role in innate immunity by acting as a pattern recognition receptor for beta-1,3-glucan from fungi and lipopolysaccharide from Gram-negative bacteria. Upon recognition of invading microorganism-derived products, acts upstream of protease spz processing enzyme SPE to activate the Toll pathway and to induce the expression of antimicrobial peptides drosomycin, cecropin and attacin.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10827089}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:10827089}. Note=Secreted and attached to the membrane by a GPI-anchor.
Interaction partners:
- Peptidoglycan-recognition protein SA
- Modular serine protease
- Peptidoglycan-recognition protein SD
- Peptidoglycan-recognition protein SC2
- Peptidoglycan-recognition protein SC1a
- Serine protease persephone
- Spaetzle-processing enzyme
- Peptidoglycan-recognition protein LC
- Protein immune deficiency
- Peptidoglycan-recognition protein LE
Sequence:
MPGLCIGILLLIGFGCTTAYKIPTPTVELLETGFSVSIPDEEGVKVVAFNVNRNRNFTSFINEGQYNVRLTEPQNGRWTTNFSSVPLRSQDVLYLWTSVQHQKAVYQDLAQPLPVCNLGGEYRPRGCSPGDDDFTDDNQLSTEDSALEPTAPSVCEPSESQVSPQIGVSICKGQLLFEETFDQLNESLWIHDVRLPLDSKDAEFVLYDGKAKVHDGNLVIEPLLWSSYRPDLSIANSRLDLSERCTGTHNRIKECILHSTGSGPSGIMPPIVTPRISTKETFAFQYGRIEIRAKLPKGDWIVPLLLLEPLTEWYGQSGYESGQLRVALARGNSVLRMPRGKLVDGRSLYGGPVLSTDAHQREDLWLSKRKISHFGDDFHTYSLDWSSNRLLFSVDGQVYGEMLNGFTELDENPRWKQGGPMAPFDKMFYISLGVSVGGFGDFVDHLRTATYEKPWANYHPQAKLQFHQAQDQWLPTWKQPALKIDYVRVFATDN
Protein: RAS protein activator like 2 (D3Z1T6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNADDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCSSASERDKWMENLRRTVQPNKDNCRRAENVLRLWII
Protein: DNA-directed RNA polymerases I and III subunit RPAC1 (Q6PHE7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAPMSNVDEIRDRVILGEFGVKNVHTTDYPGNYPGYDDTWDFEKFKKNFRIEIISSDENTLEFDMIGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKADPRLFEYRNSEDQEGTEIDTIQLQLKVKCTRNPRAPKDSSDPKELYLNHMIYSGDIKWLPIGNQADVFADAKIGPVHGDILLAQVRPGQELDIVMHCVKGIGKDHAKFSPVATASYRLLPEITLLQTIEGEQAERLKRCFSPGVIELENVNGRKVAKVVNSRLDTCSREVLRHDDLKSLVKLGRVRDHFIFSVESTGILPPDVLVTEAINVLMSKCQKFLTELEATEMD
Protein: COX assembly mitochondrial protein homolog (Cmc1p) (Q9CPZ8)
Organism: Mus musculus (Mouse)
Function: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q7Z7K0}. Note=Colocalizes with MT-CO1. {ECO:0000250|UniProtKB:Q7Z7K0}.
Interaction partners:
Sequence:
MALDPAEQHLRHVEKDVLIPKIIREKARERCSEQVEDFTRCCKDSGILMVLKCRKENSALKDCLTAYYNDPAFYEECKLEYLKEREEFRKTGVPTKKRLQKLPTNM
Protein: Global transcriptional regulator CodY (A2RHP2)
Organism: Lactococcus lactis subsp. cremoris (strain MG1363)
Function: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00621}.
Interaction partners:
- Catabolite control protein A
- Purine biosynthesis transcriptional activator PurR
- Glutamine synthetase repressor
- Aconitate hydratase
- Di-/tripeptide transporter
- Arginine repressor
- Branched-chain amino acid permease BrnQ
- Asp23/Gls24 family envelope stress response protein
- Arginine repressor
Sequence:
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYVRAAVRIYDTMANVPVDRPLAIFPEESLSDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNLKLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLGMKGTYLKVLNTGLFDKLAGRNF
Protein: Protein C19orf12 (Q9NSK7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:21981780, ECO:0000269|PubMed:22508347, ECO:0000269|PubMed:26136767}. Mitochondrion membrane {ECO:0000269|PubMed:21981780, ECO:0000269|PubMed:26136767}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum {ECO:0000269|PubMed:22508347}. Cytoplasm, cytosol {ECO:0000269|PubMed:26136767}. Note=In response to oxidative stress, relocates to the cytosol forming aggregates that partially co-localize with mitochondria. {ECO:0000269|PubMed:26136767}.
Interaction partners:
- Fatty acid 2-hydroxylase
- Pantothenate kinase 2, mitochondrial
- 85/88 kDa calcium-independent phospholipase A2
- Polyamine-transporting ATPase 13A2
- DDB1- and CUL4-associated factor 17
- WD repeat domain phosphoinositide-interacting protein 4
- Bifunctional coenzyme A synthase
Sequence:
MTIMVEDIMKLLCSLSGERKMKAAVKHSGKGALVTGAMAFVGGLVGGPPGLAVGGAVGGLLGAWMTSGQFKPVPQILMELPPAEQQRLFNEAAAIIRHLEWTDAVQLTALVMGSEALQQQLLAMLVNYVTKELRAEIQYDD
Protein: NADH-cytochrome b5 reductase (EC 1.6.2.2) (Q6NYE6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00037811}; Lipid-anchor {ECO:0000256|ARBA:ARBA00037811}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00037811}. Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00037821}; Lipid-anchor {ECO:0000256|ARBA:ARBA00037821}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00037821}.
Interaction partners:
- Cytochrome b5
- Cytochrome b5 type B
- Sulfite oxidase, mitochondrial
- Uridine 5'-monophosphate synthase
- Cytidine monophosphate-N-acetylneuraminic acid hydroxylase
- Dihydroorotate dehydrogenase
- Dihydropyrimidine dehydrogenase [NADP
- Dihydropyrimidine dehydrogenase a, tandem duplicate 1.
- Dihydropyrimidine dehydrogenase [NADP
- Iodotyrosine deiodinase
Sequence:
MSFIFNLITGSCQFVLDFLRRLFGFKSRPAITLEDPDVKYPLRLVDKEIISHDTRRFRFALKSPDHVLGLPIGQHIYLSAKIDGNLVVRPYTPVSSDDDKGFVDLVVKIYYKNIHPKFPDGGKMSQYLESLRIGDTIDFRGPSGLLVYKGKGSFAIRPDKKSDAVIKTAKHVGMIAGGTGITPMLQIIQAVMKDPKDDTVCYLLFANQTEKDILLRPELEEIMANHPTRFKLWYTVDRAPDGWEYSQGFINEDMVRKHLPSPGNETLVLMCGPPPMIQFACNPSLDKVGHSNDRRFMF
Protein: Division abnormally delayed protein (Dally protein) (Q24114)
Organism: Drosophila melanogaster (Fruit fly)
Function: Cell surface proteoglycan that bears heparan sulfate. Required for cell division patterning during postembryonic development of the nervous system. Plays a role in dpp/BMP signaling possibly by stabilizing dpp and thereby creating a morphological gradient during wing development. Might have a role in testis development.
Subcellular location: Cell membrane {ECO:0000269|PubMed:35609633}; Lipid-anchor, GPI-anchor {ECO:0000305}; Extracellular side {ECO:0000305}. Note=Localizes to the apical side of wing disk epithelia. {ECO:0000269|PubMed:35609633}.
Interaction partners:
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase
- Protein hedgehog
- Palmitoleoyl-protein carboxylesterase NOTUM
- Protein decapentaplegic
- Protein wingless
- Syndecan
- Netrin receptor unc-5
- receptor protein serine/threonine kinase
- Extracellular sulfatase SULF-1 homolog
- Dally-like, isoform A
Sequence:
MAARSVRLAQLLLFTLLCGFVGLSAAKHLDLDGIHHHQHHLHSATTHHRRRLQRDSRAKDAVGGSTHQCDAVKSYFESIDIKSSGTYSEKGAICGGNCCNNATELELRDKAAGMFEQLLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQHNFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSGEPDARPPPHKNNVKWATDPDPGMVLFLSTIDKSKEFYTTIVDNFCDEQQHSRDDHSCWSGDRFGDYTQLLINPGTDSQRYNPEVPFNAKAQTGKLNELVDKLFKIRKSIGAAAPSNSIQATHDIQNDMGEGSGGGEGQIGDDEEEYGGAHGSGDGSGDGPHTPIEESEGTTTNEVESRDSGKTSGSNPLEGTATWMLLTLVTMLFSSCS
Protein: Sodium-dependent low-affinity dicarboxylate transporter 1 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (ceNaDC1) (Q93655)
Organism: Caenorhabditis elegans
Function: Low affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MARKRGISSLLLIYKQSFVIWGALLIFSPLLMFVGDSHGLQAKCLYCVAVMGSYWVFEALPLAITAFIPMILFPLFGIMRSEEVARAYLPDTCFLFMGGLMVALAVEKCELHARVALFVLKTVGSEPARVMAGFMGVTGFLSMWISNTATTALMVPILQSVITELVSNHRMEDLVALCEAHHNSSRKHSVGMRRLSLPNENNEIKREEMDTAMSPREQKMAKGLMLSVCFSANIGGAATITGTASNLVLVGQLNELFPGADTGVNFLSWLIFAFPMVFCCLIYCWCVLYLLYLRDAPKGSIIVTRKLQQKYNELHAFSFAEMAVIFCFALLLVLWILREPQVVPGWGEMFKDEFVSDATSAMFIVILLFTLPEKLPSSRGSSEQRKASSGLLDWATVQDRFPWSVLFLLGGGFALAAGVKESGLSHDIGAIMRYLDVFNHNIIMLICIIISVTLTNVCSNTVIASIFIPIVAELARSLEIDPLNFMLPVTISASFAFLLPVATPPNAIVFSSGYLKVFDMFVSGLCVTLGCVVLSMLNMLLWAGFVFNLHLFPQWAANPSPPLDVQDWAVENNITFVGTSKL
Protein: Uncharacterized RING finger protein C6B12.07c (O14212)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glycerophosphocholine phosphodiesterase gde1
- Vacuolar transporter chaperone complex subunit 2
- Putative inorganic phosphate transporter C23D3.12
- Probable metabolite transporter C2H8.02
- Uncharacterized transporter C3B8.04c
- Serine O-succinyltransferase
- Zinc finger protein grt1
Sequence:
MKFGHDFKRALENDMPPGWGEAAIQYKALKKCIKRFVFELSSLGLSAETISKLMAPTTVDPQQAITLSYSLGKEGHIVVPKIIINVNFDKLKTDKFAASMFKQLNASNMITTVRSNYASNVPSTPSDSTQQPPTNTLPSVSASSQSVETCETVDEDIDTQTMSSDMSEVQSMEISLNCDHEFFEKLTSELQSVEGLQREQRKILFNAIDILSHEISLIASPNSKKKYKSLYCWRKIFEIYMDSDIFISCKEADQSHERTPELAERHLKWFDDQVRLAKCLPSSSKHRDRILYAKFLELNESLLKVASFQQMNKLAVTKIMKKFDKRTSLTAQPLFFQVIESDPLLLVDNASKAICFSLSSKLFSIIPQLRDFECAICSNVAYKPVRLGCSHVFCLHCLIILQKQKVDFCPLCRAKEVMKADSRNIDHALMNFMKTYFPREIKEKFEENENDTFTPSSISVVSGQNNCVIM
Protein: Enhancer of polycomb-like protein 1 (P43572)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Chromatin modification-related protein EAF3
- SWR1-complex protein 4
- Actin
- Protein AF-9 homolog
- Chromatin modification-related protein EAF6
- Chromatin modification-related protein EAF7
- Histone acetyltransferase ESA1
- Chromatin modification-related protein EAF5
- Chromatin modification-related protein YNG2
- SAGA complex/NuA4 acetyltransferase complex subunit TRA1
Sequence:
MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKISVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMGSGHTKHKDYIPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGSSDILTEDEFEILCSSFEHAIHERQPFLSMDPESILSFEELKPTLIKSDMADFNLRNQLNHEINSHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERPGEKEEIDPYVCFRRREVRHPRKTRRIDILNSQRLRALHQELKNAKDLALLVAKRENVSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAELKRAAAAAAAAKAKNNKRNNQLEDKSSRLTKQQQQQLLQQQQQQQQNALKTENGKQLANASSSSTSQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARKFVQEKMEKRKIEDADVFFNLTDDPFNPVFDMSLPKNFSTSNVPFASIASSKFQIDRSFYSSHLPEYLKGISDDIRIYDSNGRSRNKDNYNLDTKRIKKTELYDPFQENLEIHSREYPIKFRKRVGRSNIKYVDRMPNFTTSSTKSACSLMDFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDSPQNEYGIKFSDEPARLNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITRLKQKHIQHLQQQQQQQQQQQQQAQQQKQKSQNNNSNSSNSLKKLNDSLINSEAKQNSSITQKNSS
Protein: Diacylglycerol kinase alpha (DAG kinase alpha) (EC 2.7.1.107) (EC 2.7.1.93) (80 kDa diacylglycerol kinase) (Diglyceride kinase alpha) (DGK-alpha) (O88673)
Organism: Mus musculus (Mouse)
Function: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P23743}.
Interaction partners:
- Lipoprotein lipase
- Dihydroxyacetone phosphate acyltransferase
- RAS guanyl-releasing protein 1
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Phospholipase D2
- 1-acyl-sn-glycerol-3-phosphate acyltransferase beta
- Phospholipase D1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
Sequence:
MAKEKGLISPEDFAQLQKYIEYSTKRVSDVLKVFDDGEMNRFCQGDAIGYLGFEQFMKMYLEMEEVPHHLCWALFWSFHTSQVAAEKTKSKANVICLSDVYCYFTLLEGGRPEDKLEFTFKLYDMDRNGILDSTEVEKIILQMMRVAEYLDWDVSELRPILQEMMREMDQDGSGSVSLDEWVRAGATTVPLLVLLGMDVTMKDDGNHIWRPKRFTRLVYCNLCEQSISLGKQGLSCNFCKYIVHDHCAMKAQPCEVSTYAKSRKDIGVQSHLWVRGGCHSGRCDRCQKKIRTYHSLTGLHCVWCHLEIHDDCLQAVGPECDCGLLRDHILPPCSIYPSVLVSGQECKHKTTDDTSLCTPEAFRIEPVSNTHPLLVFINLKSGGKQGQSVLWKFQYILNPRQVFDLKDGPEPGLRFFKDVPQFRILVCGGDGTVGWVLETIDKANFATVPPVAVLPLGTGNDLARCLRWGRGYEGENLRKILKDIELSKVVYLDRWFLEVIPQQNGEKSDPVPSQIINNYFSIGVDASIAHRFHLMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESVTVEICGKLLDLSDLSLEGIAVLNIPSTHGGSNLWGDTKRPHGDTCEINQALGSAAKIITDPDILKTCVPDMSDKRLEVVGIEGAIEMGQIYTRLKSAGHRLAKCSEITFQTTKTLPMQIDGEPWMQAPCTIKITHKNQMPMLMGPPSNSYNFFGFWS
Protein: Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X) (Q96JZ2)
Organism: Homo sapiens (Human)
Function: May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Activated CDC42 kinase 1
- N-formyl peptide receptor 2
- Annexin A1
- Probable G-protein coupled receptor 32
- Chemerin-like receptor 1
- Leukotriene B4 receptor 1
Sequence:
MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC
Protein: Putrescine N-methyltransferase (EC 2.1.1.53) (Q9ZWT9)
Organism: Nicotiana sylvestris (Wood tobacco) (South American tobacco)
Interaction partners:
- ornithine decarboxylase
- ornithine decarboxylase
- ornithine decarboxylase
- N-carbamoylputrescine amidase
- Putrescine N-methyltransferase 3
- Putrescine N-methyltransferase 4 isoform X1
- LOW QUALITY PROTEIN: spermine synthase
- Probable polyamine oxidase 4
- Probable polyamine oxidase 4
- Probable polyamine oxidase 2
Sequence:
MEVISTNTNGSTIFKSGAIPMNGHQNGTSKHQNGHKNGTSEEQNGTISHDNGNELLGNSNCIKPGWFSEFSALWPGEAFSLKVEKLLFQGKSDYQDVMLFESATYGKVLTLDGAIQHTENGGFPYTEMIVHLPLGSIPNPKKVLIIGGGIGFTLFEMLRYPTIEKIDIVEIDDVVVDVSRKFFPYLAANFNDPRVTLVLGDGAAFVKAAQAEYYDAIIVDSSDPIGPAKDLFERPFFEAVAKALRPGGVVCTQAESIWLHMHIIKQIIANCRQVFKGSVNYAWTTVPTYPTGVIGYMLCSTEGPEIDFKNPVNPIDKETAQVKSKLAPLKFYNSDIHKAAFILPSFARSMIES
Protein: AT18578p (Q8T443)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTSFQYVFMIMIFLICSCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSTLEFMFRWGFDGVQIDWRYPTLLGGHPEDRQNFVILLEELGLIFRKNQLILMVAVLGRRDKRILESYNIPEIVKHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEGSVTDSIMHWKRNGGAPEKLILGIPLFVRSFTMDRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYATRGDQWVSYESPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRVIFSALGDKNALTTEQPTTEASGLCPHDGFSRDGWDCRLYHECRDGERIYYECLEGQYFDENQIVCRPAAEVKCDQNFVIWRPGMPVYSYDNMPLNLKIVE
Protein: Riboflavin transporter rft-1 (Solute carrier family 52, riboflavin transporter rft-1) (Q3LFN0)
Organism: Caenorhabditis elegans
Function: Riboflavin transporter. Riboflavin transport is Na(+)-independent but pH-sensitive.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Riboflavin transporter rft-2
- G-protein coupled receptors family 1 profile domain-containing protein
Sequence:
MKTFLFTFCLVAIFGSSSWIGTNSVWMELSLLTAKLPEGWNLPSYLSAIVQIACLGPLIYSIIHKGIKMTIPTVPLIFIFMVLACICQLGLCFFWDDTGYIFGAIRSWPLYLLLFGLAIVDAISSVLFLPFMAQFHPSFLNAYFVGMGLSALIPSLLSLIQGTSNYWCDDNKTPHYYPPRFSVSMFFLINFFFTCAAVAAFLVLYKIGAHKNSSQVEPEPKHSIQIIQGDSTTDVNEVNTESSFQETSSIPDSSSATGARLAFLLLTTALVNAQMNGIVTSVQSYATLVYSQNTYHYAVTLSNVISPLASYLQFFVKIRSLPILAFLTLCSSLTTAVIIYLAALSPNWIFNSETAGTIISIASSLIAAGLHSYLRVMFAALLREGNQKESRLFWCGAFIQIGSFTGSAIMFPLVNVWKLFHSAPSCR
Protein: Granulocyte-macrophage colony stimulating receptor alpha (Q701L2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MSIIPLPQLLALLCCCGLAAATQGPTDPSTPPNLGLAHFHNLTFDPGTWTLSWACGGHDGAVMSCTVIDQEAGIRRRVRSRGCRCRFQPMELHRGVDLEVAGDKGHAQVHQTLRFENEGAPGSGAENLTCEILAAHFLCCYWAVGPAAPDDIRYSLRVLNATGHEVASCSAAPGTPPTRCQADDLTHLPRLAYIVVTGQSRTGLVRFLDAVVNTKGIERLGPPDNVSASCNFSHCTITWAPPPTWAPMTEQDFRFEIEWKKAEPSSIAQKVVIAGREDNAFAFPSPAPRGRLWVRVRAGDTRSDRWSDWSPALELGSEATTPPRALVLAASSCAALLCALALGAACRRLALSRRLLPPIPGIRDRVSDDERVNSETLRKDLLRP
Protein: Auxin response factor 17 (Q84WU6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
Subcellular location: Nucleus.
Interaction partners:
- Indole-3-acetic acid-amido synthetase GH3.6
- Indole-3-acetic acid-amido synthetase GH3.5
- Indole-3-acetic acid-amido synthetase GH3.3
- Protein TRANSPORT INHIBITOR RESPONSE 1
- Auxin transporter protein 1
- Protein AUXIN SIGNALING F-BOX 2
- Transcription factor MYB33
- Squamosa promoter-binding-like protein 10
- Endoribonuclease Dicer homolog 1
- Auxin-responsive protein IAA11
Sequence:
MSPPSATAGDINHREVDPTIWRACAGASVQIPVLHSRVYYFPQGHVEHCCPLLSTLPSSTSPVPCIITSIQLLADPVTDEVFAHLILQPMTQQQFTPTNYSRFGRFDGDVDDNNKVTTFAKILTPSDANNGGGFSVPRFCADSVFPLLNFQIDPPVQKLYVTDIHGAVWDFRHIYRGTPRRHLLTTGWSKFVNSKKLIAGDSVVFMRKSADEMFIGVRRTPISSSDGGSSYYGGDEYNGYYSQSSVAKEDDGSPKKTFRRSGNGKLTAEAVTDAINRASQGLPFEVVFYPAAGWSEFVVRAEDVESSMSMYWTPGTRVKMAMETEDSSRITWFQGIVSSTYQETGPWRGSPWKQLQITWDEPEILQNVKRVNPWQVEIAAHATQLHTPFPPAKRLKYPQPGGGFLSGDDGEILYPQSGLSSAAAPDPSPSMFSYSTFPAGMQGARQYDFGSFNPTGFIGGNPPQLFTNNFLSPLPDLGKVSTEMMNFGSPPSDNLSPNSNTTNLSSGNDLVGNRGPLSKKVNSIQLFGKIITVEEHSESGPAESGLCEEDGSKESSDNETQLSLSHAPPSVPKHSNSNAGSSSQG
Protein: Uncharacterized protein orf181 (Q2F995)
Organism: Oryza sativa subsp. indica (Rice)
Interaction partners:
Sequence:
MPRDLLIKMDEKRQGYMFILEGGSISWCSKKEDCFSLSTMKSEYIACTAAVQEAIWLRNYLLCLDVTKHAYETTVIYCDNTAAILFFSTNIIPWAVQRTDHDLLLGEGMYRDKMVGEVGANTFHSNPYRCGWTRLHAKTLYSNIFSLTAPSTYFSIQLLLSQSITNRILAIHVRLASILAF
Protein: Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-) (Q8K370)
Organism: Mus musculus (Mouse)
Function: Acyl-CoA dehydrogenase only active with R- and S-2-methyl-C15-CoA.
Interaction partners:
- UBX domain-containing protein 7
Sequence:
MLVRRLFQPSTLHWAWRTTALNHPLGRHQGGLRWTHSGGRSYRAVIFDTGGVLVPSPGTVAVGWEVQNHVPSGTIVKAFIRGGDSGPWIRFIKGEITTEHFLEEFGRLCSEIAKTSVPVSSYFSLLTSEQVTKQFPVMTQAISQIRAKGLQTAVLTNNFHLSSGESFLPLDRKQFDVVVESCLEGICKPDPRIFQLCLQRLSLQPSEAIFLDDLGSNLKVAASLGIHTIKVDRPETAVKELEALLGFPLHLGVPNTRPVRKTMAIPQDALEKYLKGLLGTHSTGPMELLQFDHGQSNPTYYIRLADRQLVLRKKPSGTLLPSAHAIEREFRIMKALANAGVPVPTVLDLCEDSSIIGTPFYLMEYCPGIIYKDPSLPGLEPSRREAIYTAMNQVLCRIHSVDLQATSLDSFGKQGDYIPRQVQTWTKQYRAAETSSIPAMERLIQWLPLHLPRQQRTTLVHGDFRLDNLIFHPEKAEVLAVLDWELSTLGDPFADVAYSCLAYYLPSSFPILRGFRDQDVTKLGIPTVEEYFRMYCLNMGIPPIDNWNFYMAFSFFRVAAILQGVYKRSLTGQASSATAQQSGKLTESMAELAWDFATKEGFRVFKEMPATKTLSRSYHAWAGPRSPRTPKGVRGHSTVAAASPSHEAKGGLVISPEGLSPAVRKLYEQLVQFIEQKVYPLEPELQRHQASADRWSPSPLIEDLKEKAKAEGLWNLFLPLETDPEKKYGAGLTNVEYAHLCEVMGMSLYASEIFNCSAPDTGNMEILVRYGTEEQKARWLVPLLEGRIRSCFAMTEPQVASSDASNIEASIKEEDGCYVINGHKWWTSGILDPRCKLCVFMGKTDPQAPRHQQQSMLLVPMDSPGITVIRPLSVFGLEDPPGGHGEVRFKDVRVPKENILLGPGRGFEIAQGRLGPGRIHHCMRLIGYSERALALMKTRVMSRTAFGKPLVEQGTILADIARSRVEIEQARLLVLKAAHLMDVAGNKTAALDIAMIKMVVPSMAYHVIDRAIQAFGAAGLSSDYPLAQFFGWARALRFADGPDEVHQLTVAKMELKNQSRMQEPAVPRV
Protein: Alpha-methyl-mannoside-specific lectin (SL-I) (Q70DJ5)
Organism: Arachis hypogaea (Peanut)
Function: Alpha-methyl-D-mannoside-specific lectin. Has hemagglutinating activity towards rabbit erythrocytes. Binds to cytokinins and significantly inhibits physiological effects of cytokinin activity such as cotyledon expansion and delayed leaf senescence.
Interaction partners:
Sequence:
MAISKKILPLLSIATIFLLLLNKAHSLGSLSFGYNNFEQGDERNLILQGDATFSASKGIQLTKVDDNGTPAKSTVGRVLHSTQVRLWEKSTNRLTNFQAQFSFVINSPIDNGADGIAFFIAAPDSEIPKNSAGGTLGLSDPSTAQNPSANQVLAVEFDTFYAQDSNGWDPNYQHIGFDVDPIKSAATTKWERRNGQTLNVLVSYDANSKNLQVTASYPDGQSYQVSYNVDLRDYLPEWGRVGFSAASGQQYQSHGLQSWSFTSTLLYTSPHYLKLGRFMI