wanglab/gogpt-training-data huggingface dataset:
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme A) (Q95S49)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTIKPVSAPPSAKRVAGNVDPDNKEAQVVVVEQSVVSQTHNHAHNHRNVVIDGQSPQRRGEVYDELARTHRCSPHKSTRSKRREHHEAHAHLYKRDRLEREKLVHPTAAAGSGAPGVSGSKCNSPPSTSTSGSSSPSAVGRNSPEHLGLGCTTVPTAQVQMSTSTAATNLLKTVEETFSGYNSGDEHHQPKERLIPVEEWQRRDLEFAKCMEQRGYELKPVEEDGACLFRSISLQIYGDEEMHDVIRQHTMDYIHENREYFGQFVTEDINSYIQRKRARDAHGNHIEIQAISEIYSRTVEVYCYQSNPINIFNSEQSQAGYPPLRLSYQRGSHYNAILDPYNATVGVGLGLAGYKPEIQTKEAVRLSEQLEIEQTMFEDKLKTTDWEATNEAIEEQIARESYLQWCRENTQRSRNSNTAAGSATSSTVTSAEALTDSDASPSKYSACGGTGSSGNPPVALTSGSGGDGAGPAFSLSPKTLNQFSHKLPQEVNELGGYDSDATDMSSTSSVGHSGGSSSPSTAASQRSGKGSKSQRRATALRKKRRHETRETTLASKRLVFVATCGAAY
Protein: Sedoheptulose 1,7-bisphosphatase (EC 3.1.3.37) (P36136)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Sedoheptulose 1,7-bisphosphatase involved in riboneogenesis. Dephosphorylates sedoheptulose 1,7-bisphosphate (SBP), which is converted via the non-oxidative pentose phosphate pathway to ribose-5-phosphate. Has a fructose 1,6-bisphosphatase activity in vitro, but this is probably not biologically relevant, since deletion does not affect fructose 1,6-biphosphate (FBP) levels.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Thymidylate synthase
- Triosephosphate isomerase
- Phosphoglycerate kinase
- Fructose-bisphosphate aldolase
- Putative uridine kinase DAS2
- Transketolase 1
Sequence:
MPSLTPRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNNQFLNPDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEYGDYEGMLTREIIELRKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHRKHQSEGRASDIMVFAHGHALRYFAAIWFGLGVQKKCETIEEIQNVKSYDDDTVPYVKLESYRHLVDNPCFLLDAGGIGVLSYAHHNIDEPALELAGPFVSPPEEESQHGDV
Protein: Bowman-Birk type proteinase inhibitor 1 (LSI-1) (P86701)
Organism: Lathyrus sativus (White vetchling)
Function: Inhibits trypsin (IC(50)=6.20 nM), neutrophil elastase (ELANE) and, to a lesser extent, alpha-chymotrypsin (IC(50)=3.44 uM).
Interaction partners:
Sequence:
GDDVKSACCDTCLCTKSNPPICRCVDIRETCHSACNSCVCTASIPPQCRFCYK
Protein: BCL2-interacting protein 1b (Vesicle transport protein SEC20) (A0A0R4IG59)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}.
Interaction partners:
- Vesicle transport protein USE1
- RAD50 interactor 1.
- Vesicle-trafficking protein SEC22b-B
- Vesicle-trafficking protein SEC22b-A
- Syntaxin-18
- BCL2-interacting protein 1a
- Golgi SNAP receptor complex member 2
- NBAS subunit of NRZ tethering complex
- Zw10 kinetochore protein.
- Golgi SNAP receptor complex member 1
Sequence:
MTTNMASSSDVHVRICGQEIIKYDLEIKAIIQDIRECCGPQAVLMELNSTVKEKFSLLRQRIQDMEQMAKEQDRETDKQALLSETEGHRKQMLSNQMAWRKANLACKLAIDNLEKDELLQGGDAVRQRKATKESLVQTSSDITESLMSISRMMSQQVQQSDETIGTLVTSSRTVQETNEEFKAMTGTIHLGRKLILKYNRRELTDKLLIFLAIALFLATVLYILKKRLFPFI
Protein: Transmembrane protease serine 11E (EC 3.4.21.-) (Serine protease DESC1) (Transmembrane protease serine 11E2) [Cleaved into: Transmembrane protease serine 11E non-catalytic chain; Transmembrane protease serine 11E catalytic chain] (Q9UL52)
Organism: Homo sapiens (Human)
Function: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q5S248}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q5S248}.; SUBCELLULAR LOCATION: [Transmembrane protease serine 11E catalytic chain]: Secreted {ECO:0000250|UniProtKB:Q5S248}. Note=Activated by cleavage and secreted. {ECO:0000250|UniProtKB:Q5S248}.
Interaction partners:
- Plasma serine protease inhibitor
Sequence:
MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI
Protein: Inner membrane protein YagU (P0AAA1)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:16079137}; Multi-pass membrane protein {ECO:0000269|PubMed:16079137}.
Interaction partners:
Sequence:
MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSPVDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWVGVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDLPWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR
Protein: Protamine (Q24406)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSNNVNECKSLWNGIISISAKDESPKGLTEMCNHPKRRAPPKCKPMKSCAKPRRKAACAKATRPKVKCAPSQKCSKQGPVTNNAYLNFVRFFRKKHCDLKPQELIAEAR
Protein: Leptin (Obesity factor) (C4WYH6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKSSMIFCLLISSLVAVSISRPTAPEDRIRIIARTTISRIKKIKDEHFQMSPEIDFGPDIDNPIDGLSSVLSYLSYLQLRLHVPPAQHLQQVQIDLETLLRTLEELAVSQGCPLPNPETPVHKEETAFPVTSNYLHLLELQRFLEKLCLNIDKLKYCKDTDVAETFIL
Protein: Nuclear RNA export factor 7 (A2AEI5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MCSNERKQGSFRYTGRKKDRVSSLSYAGKRTDHYEHTGHTILPFKAQSDGGNLEMRAVLWNPSVRHTPYVGQHRSREEEHMEDQIHVTAQRDDKPEQREAGQFTEDGELGSWFKVTVPCGRKYDKTQ
Protein: Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (Q9ZU32)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the biosynthesis of NAD(+). Catalyzes the conversion of quinolate to nicotinate to nicotinate beta-D-ribonucleotide.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:16698895}.
Interaction partners:
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase
- Nicotinate phosphoribosyltransferase 1
- Nicotinate phosphoribosyltransferase 2
- L-aspartate oxidase, chloroplastic
- Quinolinate synthase, chloroplastic
- Glutamine-dependent NAD
- Nudix hydrolase 19, chloroplastic
- Probable inactive nicotinamidase At3g16190
- Haloacid dehalogenase-like hydrolase
- Alkaline-phosphatase-like family protein
Sequence:
MISVSRFLSPQFYAIPRSFVKMSASATQTAGEVSMGIKPPSHPTYDLKAVIKLALAEDAGHTGDVTCMATIPFDMEVEAYFLAKEDGIVAGVALADMIFEHVDPSLKVEWMRKDGDYVHKGLKFGKVSGNAHKIVVAERVLLNFMQRMSGIATLTKLMADAASPACILETRKTAPGLRLVDKWAVLIGGGRNHRMGLFDMVMIKDNHISAAGGIVNAVKSVDEYLKQKNLEMDVEVETRTLEEVKEVLEYASGSETRLTRIMLDNMVVPLENGDVDVTMLKDAVELINGRFETEASGNVTLETVHKIGQSGVTFISSGALTHSVKALDISLKIDTELALEVGRRTKRA
Protein: Syntaxin, putative (Q388D5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Syntaxin, putative
- Syntaxin, putative
Sequence:
MPNYLPNRDGFMRAMLRETIKRIRRVRERAGRTDEPKEIETTGDPFRDLTLAFIRCVERVKENIKERNEGAARHGQDRIAVEQSLAIHKDIRNLETILEEMKQEVNKSGAALEKETRRKKAKPHKIALLEKAHSAKSGQYKDCLATLELVKESDHQRIAATSGVNVGQELLVGRRAQLRGELGSLWRDKKDGGGHVDPYAGANLEDDTVGGGRLEDHEDTAEAMKTIAAQDKKIQNSLEVVSKGVSRLHTLALEIGGQIDMQNKHLDNTEQVMNKQTEQLHTLNVRLKKLVKEMKPMSVFLYVCCILLIMSLVGFFLMQFDVI
Protein: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A gamma isoform (AtA gamma) (PP2A, subunit A, gamma isoform) (Q38951)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: The A subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Involved during developmental process such as seedling and floral developments. Seems to act as a negative regulator of PP2A catalytic activity.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:22404109}. Nucleus {ECO:0000269|PubMed:22404109}.
Interaction partners:
- Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
- Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- Serine/threonine-protein phosphatase PP2A-4 catalytic subunit
- Serine/threonine-protein phosphatase PP2A-1 catalytic subunit
- Phytochrome-associated serine/threonine-protein phosphatase 1
- Serine/threonine-protein phosphatase 2A activator
- Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B' delta isoform
- TIP41-like protein
- Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' eta isoform
- Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' alpha isoform
Sequence:
MSMVDEPLYPIAVLIDELKNDDIQRRLNSIKRLSIIARALGEERTRKELIPFLSENNDDDDEVLLAMAEELGGFILYVGGVEYAYVLLPPLETLSTVEETCVREKAVDSLCRIGAQMRESDLVEHFTPLAKRLSAGEWFTARVSACGIFHIAYPSAPDVLKTELRSIYGQLCQDDMPMVRRAAATNLGKFAATIESAHLKTDIMSMFEDLTQDDQDSVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTDLVPAYARLLCDNEAEVRIAAAGKVTKFCRILNPELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDEKLGALCMQWLQDKVHSIREAAANNLKRLAEEFGPEWAMQHIVPQVLEMINNPHYLYRMTILRAVSLLAPVMGSEITCSKLLPAVITASKDRVPNIKFNVAKMMQSLIPIVDQAVVENMIRPCLVELSEDPDVDVRYFANQALQSIDNVMMSS
Protein: E3 ubiquitin-protein ligase Arkadia (RING finger E3 ubiquitin-protein ligase transcript variant 5 (EC 6.3.2.-)) (Ring finger protein 111) (R4KWC4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, PML body {ECO:0000256|ARBA:ARBA00004322}.
Interaction partners:
- Mothers against decapentaplegic homolog.
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MKSEISADARQKQEPLKGPLANPEPMETAKSFPAEMEVIGKAGSDFTSPLCAETRHRPSRDAGGRRDCERGLSGRKKRKSQQPGPSYCSLKEAPMSEATLTPPRHRPMLLETRSEDERNPESSLSDCASSPSSSLRFGDSDTLSSDEDGMPMTVRQQLKAHGAASTGSTGSSTGTAVGIRPLLARTRASRSHKWARLEPDSNHVKRPCLGSRRPLHRKRFVKGGAGGVTQRTPKQKERLLLQRKKREVIARKKYALLHSTSSSSEEMTSDDSSPSSTEAEHELYVDVNSSSSQASTAAVASGVLDEDVVVIEATPAPAVPASEEINVTSTDSEVEIVTVGDAFRPRSVGGHGRMHWGPSCSQSRAQEGRGRHRLSTVIQPLRQSAGEVVDLTVDEDDLSVVPTTSDSTHPQPVSSSSSSSSRNACTSASPQEGPGPSSSCSAAAPDSTLAAQSHGGVPRSGTTNTTATEDESRRSLLGENGGVAMPRLPSCCPQHSPCSGPSSGHLSMGHTHSGCMQSGATQQSGPPQPGSQHSHTHSHHFHHHHHTAPVPSSLAYQESSCPLERPTAMPAPCGGVSNQYHDQTLPVDLSSSAVRSSGSSSTGFHGTSAFDPCCPGSASRPPVYVSQAAPGPSQQTVADSFSPTIVAQPQPQPPQLSSCRHYMHPTYGSLSRPLHHQSSSSCPHSHSNAPPPQQPPPQGDYVIPHPVLPFHTPLPTHAPGHTVPTAPPPSLPSHHLPGSSAPLPQHLPPEHQALQHHLPVLGPNSVQRLHHHDLLQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSLPRQSDQRTTWELGIEAGVTVAPYPSGHLHPHLPHYHPPPRLHHFPIQLMHTGSMPEVTYPHIRYISSRMTFGRTYEDLLHLEERLGTVNRGASQGTIERCTYPHKYKKKVVERDTEEQLAPEAWASVGKKMHSTSNSRKLHGKQEEEEGAEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQLCVDQWLLTNKKCPICRVDIEAQLSSES
Protein: Uncharacterized protein At3g55240 (Uncharacterized protein T26I12.120) (Q9M3C7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized protein
- WAT1-related protein At4g16620
- SAUR-like auxin-responsive protein family
- Phosphatidylinositol 4-kinase gamma 3
- Uncharacterized protein
- Uncharacterized protein
- Putative F-box protein At3g10430
- Pentatricopeptide repeat-containing protein At4g31850, chloroplastic
Sequence:
MADSSSASYIHMVQHMIEKCLIFHMSKEECVEALSKHANITPVITSTVWKELEKENKEFFKAYEERQSKQEQMSEEETNQMIQKIISDSSKESDD
Protein: Nostrin, isoform D (M9MQH0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSQFRDNSWGQNGFEELRRYVKQGGDFSKELIFVLQERADSELIYSKSLSKLANKLNKAGREIPGSVADAWRGVATEMESRSDIHRQLAASLTDELVKPLKIVVEGHHKARKAVESNVDKAARVLGEWRASEAKAKKASHTAARENEKLQDAMLDVRIQKSPSIALLHQGPNKQAAEKELKSAEKDCVKLDNKRKKAEEAVKRADVEYYTLCVRSERARVDWEMAVLRGSAQLQSSEQQRLGNMHNFAQQYARLISDMNPILGGLSTRLQPQLDACNVAKDMQVVRHIRRNSEGPSEQLLPDFYCEHTTLAMNRERRKHALIKLLQLVKTDLERERRSRDGLRGLSQSLNHQEHQNITDKLYHIRSMLTYLEGARLKLHSALLELDHKPRATHPLAQHIHITRDRTGLQQSILKVPNWLKNNDKSQTQQSTSMLAHDITDITTNHEDELPDENCSHLHSSSHSNNNSNGSCTDVSSVVKPFNRSKSNIETNFTSQPKIISTTNAAIAVSVKSKTLANLQDGHHNNQQHHHHHHNHHSDRGQADGGSNQQDSDFDEFSSQDEDDEPQQPQQQPQPLQSQQQQQQPLLQNPTINGQVQTQHFYQNAQELQKGQKNGSVPILGRCKALYSYTPKLYDELELSPGDIIEVHAKQDDGWWLGALRNHIGIFPATYVEECA
Protein: Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (A0A140VK13)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004443}; Matrix side {ECO:0000256|ARBA:ARBA00004443}.
Interaction partners:
Sequence:
MVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLDDFPIKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGCNVSSYPGRNAREFLQCVEKALEDMFDALEGKSIKS
Protein: U-box domain-containing protein 44 (EC 2.3.2.27) (Plant U-box protein 44) (Protein SENESCENCE-ASSOCIATED E3 UBIQUITIN LIGASE 1) (RING-type E3 ubiquitin transferase PUB44) (Q9LM76)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as an E3 ubiquitin-protein ligase. Prevents premature senescence probably by targeting proteins involved in this process for degradation. Promotes the degradation of AAO3 and thus represses abscisic acid (ABA) biosynthesis.
Interaction partners:
- Disease resistance protein CHS1
- Abscisic-aldehyde oxidase
- U-box domain-containing protein 27
- DNA ligase 6
- ARM repeat superfamily protein
Sequence:
MVGSSDGDQSDDSSHFERGVDHIYEAFICPLTKEVMHDPVTLENGRTFEREAIEKWFKECRDSGRPPSCPLTSQELTSTDVSASIALRNTIEEWRSRNDAAKLDIARQSLFLGNAETDILQALMHVRQICRTIRSNRHGVRNSQLIHMIIDMLKSTSHRVRYKALQTLQVVVEGDDESKAIVAEGDTVRTLVKFLSHEPSKGREAAVSLLFELSKSEALCEKIGSIHGALILLVGLTSSNSENVSIVEKADRTLENMERSEEIVRQMASYGRLQPLLGKLLEGSPETKLSMASFLGELPLNNDVKVLVAQTVGSSLVDLMRSGDMPQREAALKALNKISSFEGSAKVLISKGILPPLIKDLFYVGPNNLPIRLKEVSATILANIVNIGYDFDKATLVSENRVENLLHLISNTGPAIQCKLLEVLVGLTSCPKTVPKVVYAIKTSGAIISLVQFIEVRENDDLRLASIKLLHNLSPFMSEELAKALCGTAGQLGSLVAIISEKTPITEEQAAAAGLLAELPDRDLGLTQEMLEVGAFEKIISKVFGIRQGDIKGMRFVNPFLEGLVRILARITFVFNKEARAINFCREHDVASLFLHLLQSNGQDNIQMVSAMALENLSLESIKLTRMPDPPPVNYCGSIFSCVRKPHVVNGLCKIHQGICSLRETFCLVEGGAVEKLVALLDHENVKVVEAALAALSSLLEDGLDVEKGVKILDEADGIRHILNVLRENRTERLTRRAVWMVERILRIEDIAREVAEEQSLSAALVDAFQNADFRTRQIAENALKHIDKIPNFSSIFPNIA
Protein: RNA-editing complex protein MP81 (Q95W15)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MRRLTRRSGRLSGKGNGGSCLQMSPTHVGAVVTWALNRLMPLHTRTIPLRCSLPTPESGTTEPRELCFYETFELTEEDVHYLLLHEAHVKHGVLLNVPPQLAPNGTPPEVPEVIMPAAQLERMGGMKLAYEPTHLPPPLHTTGARQLVLDESFYTTPTKEKKATTTAVSHVSESTAASGGRGGASATAAGTALPPRLPPDPTMKFHCSACGKAFRLKFSADHHVKLNHGSDPKAAVVDGPGEGELLGGAVTITTAKVAKHSSSAASGTASRAGDSATLDVKQQPDPQKELSAPGISAVKIPYSKAVLSLPDDELVDELLIDVWDAVAAQRDDVPKSNSANIFLPFASVVTGTADRRKEMEAVARPTARATPEGAAPGIKRPGAMAGGAVAVGKGRSGGQILPIRELIKKYPNPFGDSPNAAVQDLENEPLNPFLPEEELAAQLQVACEEDTVVTPSACTTDVSTGSVIGKKGSLEKLKEKLRGTRPSMAASAAKRRFTCPICVEKQQTLQQQQSENVGSGFCTDIPSFRLLDALLDHVESVHGEELTEDQLRELYAKQRQSTLYPQKSSTGDGAGSRETPDDSEKKEGSVGNTNMDELKSLPEEVRRVVPPAPVEQDALAVHIRAGSNALMIGRIADVQHGFLGAMTVTQYVLEVDGDERINSKGVTTPASACTPDPASTKAVEAKGEEGEVVEPEKEFIVIRCMGDNFPASLLKDQVKLGSRVLVQGTLRMNRHVDDVSKRLHAYPFIQVVPPLGYVKVVG
Protein: Disintegrin and metalloproteinase domain-containing protein 5 (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II) (tMDC II) (Q3TTE0)
Organism: Mus musculus (Mouse)
Function: This is a non catalytic metalloprotease-like protein. May play a role in sperm-egg fusion (By similarity).
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MFLLLLLFLHLKGLQAGQNPQKTTLQTTVPEKISSPDVETDAEDHMAYLITINETPHFIHLKKQSFITPTAVVYTYDRNDVQHSQPLSALENCNYNGYVAGFPNSIVTLTVCTGLRGIIQFENVSYAIEPVETLSGFVHVIYENTNKHAVIPDLGKNQSYSWFDESDYQFRSNMKKSGFTVLRQRFIMMDIIVDKKLFDYMGSDTEVVLQKVIQIIGFVNTMLSKLKLTVLINSIEIWSKENRIRLSKAVDDLLVQFSIWKHEYRSQHVAYLLAFEEHPASTGALYPGNLCKLEYNAAVALYPKGLSLESFSVIVLQLLSIGMGLTYDTENCHCTGEVCLMTPKAIYSGGVKDFSTCTLDDFKYLSTRQDLRCLQDLPLERKPARRPRRICGNGILEMNEQCDCGTLKNCTHRKCCDPMSCRLKNKATCGSGECCSQDCTVKMNDVVCRKSVDECDFVEYCNGKDPYCVPNTYARNGQYCESGEAFCFEGRCQTADKQCMSMLGKYVRGASFACYEEFNSRGDRFGNCIHNFCAFRNSLCGKLICTWPFKKLVLKANLSVAYAQIRDDLCVAMYKGGRIPKTTKTTYSNPADRDETFVNDGTICGPDMFCLRASCTETRFHMDSSKCDSTRDCNDHGVCNNLQHCHCDIGYNPPFCEEHKGQFGSVDDGHKYHVEDGKSYKQQSHSNLKKNQLQLILYISLPLLVMISAVVIKQSKLSRVCDRERSESDSSTTEDSGSNTNVTSSGGSTSH
Protein: Abl interactor 2 (A0A0C4DG21)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, filopodium {ECO:0000256|ARBA:ARBA00004486}. Cell projection, lamellipodium {ECO:0000256|ARBA:ARBA00004510}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE
Protein: Adam6 protein (Q32NZ3)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MLSLTWGMRLVERPVVPRVLLLLFALWLLLLVPVWCSQGHPTWRYISSEVVIPRKEIYHTKGLQAQRLLSYSLRFRGQRHIIHLRRKTLIWPRHLLLTTQDDQGALQMEYPFFPVDCYYIGYLEGILQSMVTVDTCYGGLSGVIKLDNLTYEIKPLNDSQSFEHLVSQIVSESDDTGPMNAWKHWSHNTGSPSSRLEYADGAPRLSSKNYATHPAAIKGHFQATHSVYSASGGDKLSSTVEYLFKVISLMDTYLTNLHMRYYVFLMTVYTEADPFSQDFRVPGGQAHTFYERVFYAHFRPDAGAIINKNSPGDDAVNPAERSICSPSALICLGQHGRNPLFLSIIITNRVGRSLGLKHDEGYCICQRRNTCIMFKNPQLTDAFSNCSLAEISNILNTPDLMPCLFYDRHVYYNTSLTYKFCGNFKVDNNEQCDCGSQKACYSDPCCGNDCRLTPGSICDKELCCANCTYSPSGTLCRPIQNICDLPEYCSGSKFICPDDTYLQDGTPCSEEGYCYKGNCTDRNIQCMEIFGVSAKNANIKCYDINKQRFRFGHCTRAEESLTFNACADQDKLCGRLQCTNVTNLPFLQEHVSFHQSVISGVTCFGLDEHRGTETADAGLVRHGTPCSRGKFCDRGACNGSLSRLGYDCTPEKCNFRGVCNNRRNCHCHFGWSPPKCKEEGHSGSIDSGSPPVQRRIIKQNLEPVVYLRIKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
Protein: Tetraspanin (Q7K010)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
Interaction partners:
- Uncharacterized protein, isoform I
Sequence:
MASTSSVKLIVYALDVLCTLLALVLISFGIYVAVSYNLNEIGQLTAYGYVGLGAAALLVVLWGYLSAWRENVCCTVTFIIFLCLVIIAQFAVVYLLITQEKTVASNLANALEATWEEELNSPGAMSLYQNWFQCCGRGSPQDYIVNERLPPETCFRNHDKSKPENLIHTGCRVEFENYWQHLTKIFNILALVLIGFELLLSVISCRLCNSIRNDARRSYF
Protein: Olfactory receptor 2F1 (Olfactory receptor 2F3) (Olfactory receptor 2F4) (Olfactory receptor 2F5) (Olfactory receptor-like protein OLF3) (Q13607)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MGTDNQTWVSEFILLGLSSDWDTRVSLFVLFLVMYVVTVLGNCLIVLLIRLDSRLHTPMYFFLTNLSLVDVSYATSVVPQLLAHFLAEHKAIPFQSCAAQLFFSLALGGIEFVLLAVMAYDRYVAVCDALRYSAIMHGGLCARLAITSWVSGFISSPVQTAITFQLPMCRNKFIDHISCELLAVVRLACVDTSSNEVTIMVSSIVLLMTPFCLVLLSYIQIISTILKIQSREGRKKAFHTCASHLTVVALCYGVAIFTYIQPHSSPSVLQEKLFSVFYAILTPMLNPMIYSLRNKEVKGAWQKLLWKFSGLTSKLAT
Protein: nicotinamidase (EC 3.5.1.19) (Nicotinamide deamidase) (A0A1D8PRE2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Nicotinate phosphoribosyltransferase
- Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase
- NAD-dependent protein deacetylase HST1
- NAD-dependent histone deacetylase SIR2
- NAD-dependent histone deacetylase HST3
- NAD-dependent protein deacylase
- NAD-dependent protein deacetylase HST2
- Purine nucleoside phosphorylase
Sequence:
MKKTALIVVDLQEDFLPPNGSLAIKNGRSVIPKINQLLPSQDNHSKFDWSLIVATQDWHPPNHTSFASQHENVAPFTEIEFIHPEKKLDPKTNQPIVMNQIVWPDHCVQGTKGAQLEPSFANQFEKLTKQDDNNTAPCKIVKKGYLPDREYYSCFQDCWGLHHTELIDLLHEYDIENVVFVGLAYDFCVLSSAIDSAKNGFKTFVLKNYCESVYPEKINDTDKLFIDNGVTIVDNDEKFDSLFK
Protein: UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (Q4V8I9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Phosphoglucomutase-1
- UDP-glucose 4-epimerase
- Galactose-1-phosphate uridylyltransferase
- Glycogen [starch] synthase, muscle
- Glycogen [starch] synthase, liver
- Glycogen phosphorylase, liver form
- Glycogen phosphorylase, brain form
- Glycogen phosphorylase, muscle form
- UDP-glucose 6-dehydrogenase
- Phosphoglucomutase 2-like 1
Sequence:
MSRFVQDLSKAMSQDGASQFQEVILQELELSVKKELEKILTTATSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNPKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH
Protein: Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta) (P23726)
Organism: Bos taurus (Bovine)
Function: Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy. Promotes nuclear translocation of XBP1 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
Interaction partners:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
- Phosphatidylinositol 3-kinase regulatory subunit alpha
- Phosphatidylinositol 3-kinase regulatory subunit gamma
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- Receptor protein-tyrosine kinase
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Insulin receptor substrate 1
- non-specific serine/threonine protein kinase
Sequence:
MAGPEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGNERCPQSVGWMPGLNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPRDGPPEPGLTLPDLPEQFSPPDVAPPILVKLVEAIERTGLDSYRPEPPAVRTDWSLSDVEQWDAAALSDGVKGFLLALPAPLVTPEAAAEAHRALREAAGPVGPALEPPTLPLHHALTLRFLLQHLGRVAGRAPAPGPAVRALGATFGPLLLRAPPPPSPPPGGAPDGTEPTPDFPALLVEKLLQEHLEEQEVAPPALPPKPPKTKPAPTGLANGGSPPSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLITHYRHESLAQYNAKLDTRLLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQELRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQYSLMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR