wanglab/gogpt-training-data huggingface dataset:
Protein: Glycogen [starch] synthase, liver (EC 2.4.1.11) (Glycogen synthase 2) (P54840)
Organism: Homo sapiens (Human)
Function: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Interaction partners:
- 1,4-alpha-glucan-branching enzyme
- Protein phosphatase 1 regulatory subunit 3C
- Glycogenin-2
- Protein phosphatase 1 regulatory subunit 3B
- Glycogenin-1
- Glycogen phosphorylase, liver form
- UTP--glucose-1-phosphate uridylyltransferase
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Protein phosphatase 1 regulatory subunit 3A
- Glycogen phosphorylase, brain form
Sequence:
MLRGRSLSVTSLGGLPQWEVEELPVEELLLFEVAWEVTNKVGGIYTVIQTKAKTTADEWGENYFLIGPYFEHNMKTQVEQCEPVNDAVRRAVDAMNKHGCQVHFGRWLIEGSPYVVLFDIGYSAWNLDRWKGDLWEACSVGIPYHDREANDMLIFGSLTAWFLKEVTDHADGKYVVAQFHEWQAGIGLILSRARKLPIATIFTTHATLLGRYLCAANIDFYNHLDKFNIDKEAGERQIYHRYCMERASVHCAHVFTTVSEITAIEAEHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRLNFLLRMHKSDITVMVFFIMPAKTNNFNVETLKGQAVRKQLWDVAHSVKEKFGKKLYDALLRGEIPDLNDILDRDDLTIMKRAIFSTQRQSLPPVTTHNMIDDSTDPILSTIRRIGLFNNRTDRVKVILHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQEHVADPTAYGIYIVDRRFRSPDDSCNQLTKFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRYYQHARHLTLSRAFPDKFHVELTSPPTTEGFKYPRPSSVPPSPSGSQASSPQSSDVEDEVEDERYDEEEEAERDRLNIKSPFSLSHVPHGKKKLHGEYKN
Protein: Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Q9EQZ6)
Organism: Mus musculus (Mouse)
Function: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.
Subcellular location: Cytoplasm. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Ras-related protein Rap-1b
- ATP-binding cassette sub-family C member 8
- Protein piccolo
- Adenylate cyclase type 8
- Adenylate cyclase type 6
- Ras-related protein Rap-1A
- Adenylate cyclase type 1
- Adenylate cyclase type 5
- Adenylate cyclase type 9
- Adenylate cyclase type 7
Sequence:
MVAAHAAHSQSSAEWIACLDKRPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQEDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPAHTITKVPSEKILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRAANQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEATDSVLNDFVMMHCVFMPNTQLCPALVAHYHAQPSQGTEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFYVSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
Protein: THO complex subunit HPR1 (Hyperrecombination protein 1) (P17629)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase. It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:11060033, ECO:0000269|PubMed:14562095}.
Interaction partners:
- ATP-dependent RNA helicase SUB2
- RNA annealing protein YRA1
- THO complex subunit 2
- THO complex subunit MFT1
- THO complex subunit THP2
- Protein TEX1
- Nuclear cap-binding protein subunit 2
- Large ribosomal subunit protein bL27m
- Serine/arginine
- Small ribosomal subunit protein bS16m
Sequence:
MSNTEELIQNSIGFLQKTFKALPVSFDSIRHEPLPSSMLHASVLNFEWEPLEKNISAIHDRDSLIDIILKRFIIDSMTNAIEDEEENNLEKGLLNSCIGLDFVYNSRFNRSNPASWGNTFFELFSTIIDLLNSPSTFLKFWPYAESRIEWFKMNTSVEPVSLGESNLISYKQPLYEKLRHWNDILAKLENNDILNTVKHYNMKYKLENFLSELLPINEESNFNRSASISALQESDNEWNRSARERESNRSSDVIFAADYNFVFYHLIICPIEFAFSDLEYKNDVDRSLSPLLDAILEIEENFYSKIKMNNRTRYSLEEALNTEYYANYDVMTPKLPVYMKHSNAMKMDRNEFWANLQNIKESDDYTLRPTIMDISLSNTTCLYKQLTQEDDDYYRKQFILQLCFTTNLIRNLISSDETRNFYKSCYLRENPLSDIDFENLDEVNKKRGLNLCSYICDNRVLKFYKIKDPDFYRVIRKLMSSDEKFTTAKIDGFKEFQNFRISKEKIPPPAFDETFKKFTFIKMGNKLINNVWKIPTGLDKIEQEVKKPEGVYEAAQAKWESKISSETSGGEAKDEIIRQWQTLRFLRSRYLFDFDKVNEKTGVDGLFEEPRKVEALDDSFKEKLLYKINQEHRKKLQDAREYKIGKERKKRALEEEASFPEREQKIKSQRINSASQTEGDELKSEQTQPKGEISEENTKIKSSEVSSQDPDSGVAGEFAPQNTTAQLENPKTEDNNAATSNISNGSSTQDMK
Protein: Insulin-like growth factor 2 (Insulin-like growth factor II) (A4GUE9)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU000406}.
Interaction partners:
- Tyrosine-protein kinase receptor
- Tyrosine-protein kinase receptor
- Cation-independent mannose-6-phosphate receptor-like
- Cation-independent mannose-6-phosphate receptor-like isoform X1
- receptor protein-tyrosine kinase
- Tyrosine-protein kinase receptor
- Insulin-like growth factor-binding protein 1
- Insulin-like growth factor-binding protein 2-A
- IGF binding protein 6 precursor
- Insulin-like growth factor-binding protein 1
Sequence:
METQKRHEHHSVCHTCRRTENTRMKVKMMSSSNRVLVIALALTLYIVEVASAETLCGGELVDALQFVCEDRGFYFSRPTSRSNSRRSQNRGIVEECCFRSCDLNLLEQYCAKPAKSERDVSATSLQVIPMVPTLKQDVPRKHVTVKYSKYEVWQRKAAQRLRRGVPAILRARKFRRQAVKIKAQEQAMFHRPLITLPSKLPPVLPPTDNYVSHN
Protein: Cell division protein FtsB (P0A6S5)
Organism: Escherichia coli (strain K12)
Function: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00599, ECO:0000269|PubMed:11972052, ECO:0000269|PubMed:15165235}; Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00599, ECO:0000269|PubMed:11972052, ECO:0000269|PubMed:15165235}. Note=Localizes to the division septum. Localization requires FtsQ and FtsL, but not FtsW and FtsI. Localization of FtsB and FtsL is codependent.
Interaction partners:
- Cell division protein FtsL
- Cell division protein FtsQ
- Peptidoglycan D,D-transpeptidase FtsI
- Cell division protein FtsZ
- Cell division protein FtsN
- Cell division protein FtsA
- DNA translocase FtsK
- Cell division protein ZipA
- Probable peptidoglycan glycosyltransferase FtsW
- Cell division protein ZapA
Sequence:
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
Protein: Prostaglandin D2 receptor (PGD receptor) (PGD2 receptor) (Prostanoid DP receptor) (Q9R261)
Organism: Rattus norvegicus (Rat)
Function: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Prostaglandin D2 receptor 2
Sequence:
MNESYRCQAATWVERGSSATMGGVAFSAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNRSLKELLPASGNQLCEAFAFLMSFFGLASTLQLLAMALECWLSLGHPFFYQRHITARRGVLVAPVAGAFSLAFCALPFAGFGKFVQYCPGTWCFIQMIHKKRSFSVIGFSVLYSSLMALLVLATVVCNLGAMSNLYAMHRRQRHHPRRCSRDRAQSGSDYRHGSPNPLEELDHFVLLALTTVLFTMCSLPLIYRAYYGAFKLVDRADGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKTFTRPLIYRNWCSHSWQTNMESTL
Protein: Early nodulin-like protein 17 (AtENODL17) (Lamin-like protein ENODL17) (Phytocyanin-like protein ENODL17) (Q39131)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000255}; Lipid-anchor, GPI-anchor {ECO:0000255}.
Interaction partners:
- Protein CROWDED NUCLEI 1
- SKU5-similar 6
- Early nodulin-like protein 8
- NAD
- MATH domain and coiled-coil domain-containing protein At3g44800
- At5g38195
- Early nodulin-like protein 10
- Non-specific lipid transfer protein GPI-anchored 7
- Early nodulin-like protein 11
- AT3g13990/MDC16_11)
Sequence:
MARFTVLITAVVLAFLMAAPMPGVTAKKYTVGENKFWNPNINYTIWAQGKHFYLGDWLYFVFDRNQHNILEVNKTDYEGCIADHPIRNWTRGAGRDIVTLNQTKHYYLLDGKGGCYGGMKLSVKVEKLPPPPKSAPVKNIGSVSMVTGLAQFMIPVSLFAFPAMWDVISRMW
Protein: STIM1L (Stromal interaction molecule 1) (G0XQ39)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRLVEGEAGHFLTSRVSLRRMRSLSSGQSFSSEGYGTSSPSASAAASCSSSITTITTTTTTTTTFTTVHVHPVYYHHSTSYFLQMEPYPDTPPSDSTAVMPGHSESLGDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGSIGEETDSSPGRKKFPLKIFKKPLKK
Protein: Putative L-type lectin-domain containing receptor kinase I.11 (LecRK-I.11) (EC 2.7.11.1) (Q9FJI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MASERLHLILLVFFNHLTFLLSQQEEAGFIYNGFGQAQAGLHLDGAAKILFPDGLLQLTNASTQQMGHAFFKKPFKFDSYEKKLSFSTHFVCALVPKPGADGGHGIAFVVSSSIDFTQADPTQYLGLLNISTNGSPSSQLLAIELDTVESAEFDDIDKNHVGIDIKSLNSVESASASYFSNAKGKNQSIKLLSGDPIQIWVDYEGALLNVTVAPLSIQKPNHPLLSRSINLTDIFPDRKLFFGFSAATGTLVSYQYILGWSFSRSRMLLQSLDFSKLPQIPHPKAKQEQTSPLLIVLLMLLVLIMLAVLGGIYLYRRKKYAEVREVWEKEYSPHRFSYKSLYKATNRFDKDGRLGKGGFGEVYRGNLPHVGDIAVKRVCHDAKQGMKQFVAEVVTMGSLKHRNLVPLLGYCRRKGELLLVSEYMSNGSLDQYLFHREKPALSWSQRLVILKDIASALSYLHTGANQVVLHRDIKASNVMLDSEFNGRLGDFGMARFEDYGDSVPVTAAVGTMGYMAPELTTMGTSTRTDVYAFGVLMLEVTCGRRPLDPKIPSEKRHLIKWVCDCWRRDSIVDAIDTRLGGQYSVEETVMVLKLGLICTNIVAESRPTMEQVIQYINQNLPLPNFSPGSLGIGVSTPVLLESVFNSRSSLAPSISPPSSHNSMFVTHTITYGDGR
Protein: Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2) (P15655)
Organism: Mus musculus (Mouse)
Function: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Also acts as an integrin ligand which is required for FGF2 signaling (By similarity). Binds to integrin ITGAV:ITGB3 (By similarity). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity). Functions as a potent mitogen in vitro (By similarity). Can induce angiogenesis (By similarity). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P09038}. Nucleus {ECO:0000250|UniProtKB:P09038}. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity). {ECO:0000250|UniProtKB:P09038}.
Interaction partners:
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 4
- Basement membrane-specific heparan sulfate proteoglycan core protein
- Vascular endothelial growth factor receptor 2
- Syndecan-1
- Syndecan-4
- Epidermal growth factor receptor
- Platelet-derived growth factor receptor alpha
Sequence:
MAASGITSLPALPEDGGAAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHVKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTEECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
Protein: Proteasome regulatory non-ATP-ase subunit 1 (Q8WRU8)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MSDNRKAVDVTVLSEDPKKKENEKKAREAESLKMSEEDERIKGQVELLVTRVGDSNTELAAVAVDQLIDLLRTHTSGSVASVPKPLKYVRSMYGQLERVQKETTNPKLAVRLHDVLSFVAMTIEFPDGQRPALEHKLLGTQDDLAHWGHEYLRFLAGCISTEWKERVSKGESVVHLDGFVQQIVSYMVKHQDEPTAVDLLMEVENIKAIIPFIDGHNHRRIASYLAAASKYLTRPMDTEALRVVYDIYVKMESYTEALFVALQLGDRAAVENLFKMCEKSSVSLQMALSCARYRFFLPNDNEEQGILSSANGNMKLSELYRHVATELDAMTPLTPEDIFKTGLDGKQSSSASDSSFKLACSFASGLVNCGYGKDMYLTGEEATWPSEQTDNRLFATTSMLGLIHLWDHADGLLEIEKYLHSDAVNIRAGACLATGISLCGVSHPYDPALGLLNDFVCAPHKEVRIGAILGLGYAYAGSMREEIRELLVPILIDGEQTMEVQCLTALALSMVFVGSTDEGMVETITHILLEMPEKDLKESATCYIILALGCLFLGRQEAADTLLDTLQTSSPIIRRYAEIVVRSCAYAATGNVVVIQNFFHAIAENDEPEDTEVPAAEGDGNGQQQKKNRQQQSTENAAHLNYKAAAVLGIALVALGEDIGTEMAKRSIIHTLLVDTVSKGEANISGRHAIPLAYALLSASNPGMQVVETLNRLLHDSDMLTAINAIVAMGIVAAGSNNARVVSKLRNLALYYQKDRFASYLFSVRLAQGFTMMGRGHLTLSPLLNDRSLVSPTALMGLLVFLHSALNFEEIILGKYSYMVSSIAPSINPRMVLAVDDQMEVVKDGVQVRVGLPVDTVAVAGKPKSITGFQTQTTPTLISVTDKVEVASQKYRPVASVVEGTFVVEEKPNVE
Protein: Eye-enriched kainate receptor, isoform A (Q9V4E9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}.
Interaction partners:
Sequence:
MLIASGFLLFQFLSYGLGVPPLVRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEYVNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNIGRSAHDFSINVYPSKQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVSRDSYVSALNEFKGKEIHNIIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQSHSLTLLNISCEEENSWDGGLSLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDAGSMNVTLVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRVCN
Protein: T. brucei spp.-specific protein (Q57YR4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWEAACLDGSLKGVQQETLRFEEDSGLHERDSPTIWSKNSLRYHDTTQPYVRDGEEKQRQHTNVHSIVLSDLDNSGEDAPQMQLNEHSVNTSRVLFTSRADFTSFCSVEEKNPENAEVATRRALTIHNNARQILQAYRALKFTIEQQVYRRYFLKWLQLHWSRGPVGGPIQTSAALPLCSTPQVVKRQLEDGMEGLLWDTASKSTPLSVPSSIKYGLSSTGHSGSNRRQELQSDGQPYESTPRNSPWSATKEPSCKLAYGEKHNTPSTSATPSNKDSSLYSCNVSSIHPDRGTPQREEFPCLRLPALGTPRSQSVN
Protein: CRAL-TRIO domain-containing protein (C4ALD5)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGDYDGKMTMKAEDILHVLRDGIAVLPGGRCRAGQAVIVCPSREQPVNQDNLRNVFLYLFEVTSKMAREKGFLVVIDMRGKQTWTNVRHILKALSSIESSSTVQVFIIKPEKFWEKQKAQMSLGTWDFEVEMISFESLIKIIDSSHLPKTVGGSYPYDHDEWLELRLDLEKWIWNITEIMEKLESVRREICEGEQPVDVTTANAALKKSQHAKNSIFNVPVEGIETEGNKIATRILKPSKGVKNPDLEATTPYISNLTDSLRLLKGEVAKNWEVRQMELSKVYQQKQFERDAEHMIETLRPYKKACERSMGDVGGCANDVVRLSAEFEQFQIAVRGMEVSVKQVFDKENHLRTIGARNQITDHVAARLAEEWHLVKELMERRSAVLHNAKEFFTSAQRYFAEVPRWTAQPGVNPNDVLFNQESLEEAIRKHDAFWAQVEEVYAQAYDDASKVTRALKEADAEDNVAREHSSRLQRAHKQLMEKWKERQVLLHHMLAMIAFETDVRLVVDWLEQHGEPYLRRNIHIGENVNQARSFQRNHTNFQRVAANTYGNVQKLHQVYQDVTKSGSKICDVDTMHGLMTDLSAKIEKFTKIENSRELLLRQSVLFHTHYKELTDWYGKMGEKYKDRRIDLTVPTCDKNKERFVLETDETAQAYAMTIDEGKTLIEMMQRATRVFDVDYSASVAHIQLLISDIEDKNTQISSEWSPRRTLLHIASKFAMFEQNQFEVLEQIKSWEVDMREMAESDSFYDKADSVLPFHKDNQQQVRNAIADIQKSAKELSQALYSQKLTDLRDKRDRVVLEAIREHVRELEIAESRVMTYANETSMRMQAASEVGDLRRISNSVCKLIDNQLSALTQLGVIPNDYNDTVQKQEELRAFRDAVQHKLKEPYDAFVIRFRELMENRLANRDEVVYHNEAIQAKYCRLMNLCEDRNKLLKSAHGCYKTYETAVLPILNQLESEYHSPTVTDWCAGCTSSIDADRAAYVADLLSKHMDYKERFGKGCTYALRNGDFLLRYIRRSTVNQSERKRHETKIADMKNNIRERQSNILELWMQKKLLLEGCQSFIFIEASAKELLEFMKGEGNRKLKHFEKKGRRESTDDDDEFAKFKSEVKQKKTDIQTFLMLSTNETMSRGVHGDEIDRCIEQVKDEFSRFSRRVGDCEVVLRGENGSTQSSKDEFSLDRHSDTAIFNEKKINERREENRKMLEPMRELIQSERDYIKDLERCVNIYVKEFDQAAKNGTIPTLNPLKYEIFGNIEKIFKFHNDKLLHELIKYENQPEAVGASFIVWIDLLNELYTEYCVNKEQKNHVIATPDAVSFFTGIRERHGLEINNEIASLLIKPVQRITRYRLLIEQLMRSCTDKTNDLKEAYEVVCSVPRKVNDLIHYNCLDLKDFKVDELGPFVTQDTLTFWEPRAYFKGRGKERQVFLFDISIVFAKRIEVSPKNIKYVIKGKPLPLSEVSIVEHVEGDTCRFGLRVGTVSSNDNRIDLKANNHHTKVKWVQKIRDLTAGMLPLGLGVSEAYSVGTLSTARSVSVRSGASTSSGGENRQSQDVESLLRHRYSVHSCDSEQSSEVWIVTADFDGQVEGHLTVHKGDRVEIVEDQATDCAEYVQVVLCDQPTKHGLVPASIIAPPESGSVPDRPDDSNASGSTVSKRKSLRRIFANSSKERAAAANSSSSNNNSPATRQSTSTSSPVTANGHTTESSTSAPIGVLSSGEPTSSNSIPSSSTPTHTVPSSVPATVIPIVVAEDEKAEDCLPPPMENITINNSIDEKDMNEDSVAASDAVEPEVALPAKVEKTPEETARFKRSYVLMELVETEQDYVKDLTSVVEGYIGNLNKMDLPADLVGKDKIIFANIVNILEFHKTNFLKEIEKCSENYEAAGAAFVKYERRLHTLYVTYCQNKPKSDYLLAQDDFEAFFADTKAKLGHKVALCDLLIKPVQRIMKYQLLLKDILKFTERAKDKTDTLKKALQVMHVVPKACDDMMQVGRLQNFDKSLSAQGKLIHQGTLQISESIAGNVQKPKDRRIFLFEQSAIIADHIPPKKEFGNPTYIFKSQFMVNKMVFEPNVPDDPLRFVIKSSDPTQPTSFIANAQSQEEKDEWNRKMSELLDQQKRLLAALVDPRRYNDMSSGMGDLSL
Protein: DNA-binding protein BIN4 (Protein BRASSINOSTEROID INSENSITIVE 4) (Protein MIDGET) (Q9FLU1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the DNA topoisomerase VI complex. Binds to DNA. Required for chromatin organization and progression of endoreduplication cycles. The loss of BIN4 activates the ATM- and ATR-dependent DNA damage responses in postmitotic cells and induces the ectopic expression of the mitotic G2/M-specific cyclin B1;1 gene in non-dividing cells.
Subcellular location: Nucleus {ECO:0000269|PubMed:17951446, ECO:0000269|PubMed:18055605}.
Interaction partners:
- DNA topoisomerase 6 subunit B
- DNA topoisomerase 6 subunit A
- DNA-binding protein RHL1
- U-box domain-containing protein 7
- Probable E3 ubiquitin-protein ligase LUL4
- Transmembrane protein
- Alpha/beta-Hydrolases superfamily protein
- Probable E3 ubiquitin-protein ligase LUL1
- Meiotic recombination protein SPO11-2
Sequence:
MSSSSREGSPDWLRSYEAPMTTSLLSLSSSDDDSPYRESEVISSLPLPDDDGDDIVVLETESVELLTRKNSETKVVTKQVSIEQVFSRKKKADASLNLEDSCAGKENGNNVDCEKLSSKHKDAQGGADSVWLVSSDSEPSSPIKQEVTVSTEKDADFVLEATEEEPAVKTVRKEKSPKTKSKSSRKTPKEGNSAQEILKTEDKDTDTTIAEQVTPEKSPKTKSKSSRKTPKEENCAQEILKTEDKDKDTDTDTIIAEEVTTDQKIKPSSGSSSRLPLVLSEKVNRTKVLVECEGDSIDLSGDMGAVGRVVVSDTTGDMYLDLKGTIYKSTIIPSRTFCVVNVGQTEAKIEAIMNDFIQLIPQSNVYEAETMVEGTLEGFTFESDDESNKNAKTAVKPADQSVGTEEETNTKAKPKAKAKGETVIGKKRGRPSKEKQPPAKKARNSAPKKPKAKK
Protein: SEC23-interacting protein (Q6NZC7)
Organism: Mus musculus (Mouse)
Function: Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Endoplasmic reticulum {ECO:0000305}.
Interaction partners:
- Protein transport protein Sec23A
- Protein SEC13 homolog
- Protein transport protein Sec31A
- Protein transport protein Sec24A
- Sec1 family domain-containing protein 1
- Vesicle-trafficking protein SEC22b
- SEC24 homolog D, COPII coat complex component)
- SEC24 homolog B, COPII coat complex component)
- Coatomer subunit beta
Sequence:
MADRKANGGGASASSSGTNLLFSSSATEFSFNVPFIPVTQAAASPASLLLPGEDSTDVGEEDSFLGQTSTHTSTPQTFSYFSQVSSSSDPFGNIGQSPLTTSAMSAGQSALPKPPATLAFTTGSQDALSAFPPSVSKAPGATPPSQMGTSTYSPSQPSSLPPNFGSPPQGIPQQGHNPYRHTPVSSRANPYITPPQLQQCQMPGHSSYPPPSGPPVQTYQMPPGPLPPLPTAMQSPAQQQVPARPAGPLVQGPSPFVLQNQYEPVQPHWFYCKEVEYKQLWMPFSVLDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKSVYWEEEPTEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVSTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDSLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECVDDFRVVSLKLLQTHFKKSVDEGKVSRVEFLPVHWHSALGGHATGVDRNIKKITLPSIGRFRHFTNETLLDVLFYNSPTYCQAIVEKVEVEINRLHSLFMSRNPNFKGKVSVAGHSLGSLILFDILSNQRDMCVSKSPGSVAVSNGVIKHSQFQEKLISEESKLMSDESCDLDVEDEEPLTLHGTLEALSLFDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKLKAAKLEQKKAAAEKKAALAALTKGQDESAPKTKEMASPSSESNESKRKLSVGAYVSSVRVDYESFEVGTGQVSVAYSSLDFEPEIFFALGSPIGMLLTIRGVARIDEKYRLPTCKGFFNIYHPLDPVAYRLEPMIAPDLDLKAVLVPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSTTQLQEELEKVANQIKEEEEKQVVEAKKKKESPELSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWGSEDTALLLLKEIYRTMNISPEQPQH
Protein: C-X-C motif chemokine 13 (Angie) (B cell-attracting chemokine 1) (BCA-1) (B lymphocyte chemoattractant) (CXC chemokine BLC) (Small-inducible cytokine B13) (O43927)
Organism: Homo sapiens (Human)
Function: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.
Subcellular location: Secreted.
Interaction partners:
- C-C chemokine receptor type 7
- C-X-C chemokine receptor type 5
- Platelet factor 4 variant
- C-X-C chemokine receptor type 4
- C-C motif chemokine 19
- C-C motif chemokine 2
- C-C motif chemokine 28
- C-X-C chemokine receptor type 3
- C-X-C chemokine receptor type 2
- C-C motif chemokine ligand 4 like 2.
Sequence:
MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP
Protein: Multiprotein-bridging factor 1, putative (Q8II81)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Small ribosomal subunit protein eS30
- 40S ribosomal protein S3
- 40S ribosomal protein S10, putative
- Small ribosomal subunit protein uS5
- 40S ribosomal protein S19
- 40S ribosomal protein S21
- Small ribosomal subunit protein eS1
- 40S ribosomal protein S16, putative
- 40S ribosomal protein S15
- Ribosomal protein S27a, putative
Sequence:
MDHQDLKPVIWHKTEKKTKPKDIHEARKLGIDVEVEKKYFGGKNKSSKGNLIIENKAKIEQETENFKIDRVTPAFSRALQQARISKKLTQAQLARLVNESESVIKEYENGKAIPNNVIIQKLNKVLGVNLPSPKKK
Protein: Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit) (P00159)
Organism: Rattus norvegicus (Rat)
Function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:6326133}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P00157}.
Interaction partners:
- Cytochrome b-c1 complex subunit 7
- Cytochrome b-c1 complex subunit 10
- NADH-ubiquinone oxidoreductase chain 5
- Cytochrome b-c1 complex subunit 8
- Ubiquinol-cytochrome c reductase, complex III subunit X.
- Cytochrome b-c1 complex subunit 10
- Cytochrome c oxidase subunit 1
- NADH-ubiquinone oxidoreductase chain 1
- NADH-ubiquinone oxidoreductase chain 4
- Cytochrome b-c1 complex subunit 6, mitochondrial
Sequence:
MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYTFLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVFMLLLFLMTLVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALILSILILAFLPFLHTSKQRSLTFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIVEDKMLKWN