wanglab/gogpt-training-data huggingface dataset:
Protein: Atlastin GTPase 1 (Atlastin-1 isoform X1) (E9QGX9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MARDKKDRDSWGSFVDKNVYDWSSEEEEADGRARPVQVLVVKDDHTFELDEAALSKILLSEEVRDREVVAISVAGAFRKGKSFLMDFMLRYMYSQASEKWLGDAEEPLTGFSWRGGSERETTGIQIWSEVFLVDKPDGSKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSMQVYNISQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFPYGQEGGMKFLEKRLKISENQHEELQNVRKHIHSCFTNISCFLMPHPGLKVATNPHFDGRLREIDQEFINNLQVLVPCLLRPKNLDVKEINGSKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAKDLYNRKMEVVSGGDRPFLAPSELQARHLEIREEALALFRSVKKMGGEEFSRRYLLQLETEIDELFVQYIKHNDSKNIFHAARTPATLFVVIFVMYVAAGITGFVGVDVIASVCNMVLGFALITLCTWAYIRYSGEYRELGAVIDQVAGALWDQGNTNEALYKLYSVAANHRQLYNHAFPGHQSDQQPEQDKKRN
Protein: Protein CASPARIAN STRIP INTEGRITY FACTOR 2 (O65684)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Peptide hormone required for contiguous Casparian strip diffusion barrier formation in roots via the regulation of CASPs protein expression and distribution in a GSO1-GSO2 signaling pathway. The Casparian strip is required for ion homeostasis (e.g. iron and potassium ions).
Interaction partners:
- Transmembrane protein
- At4g37295
- LRR receptor-like serine/threonine-protein kinase GSO1
- PAMP-induced secreted peptide 2
- Precursor of CEP16
- At2g23270
- F28L1.2 protein
- Precursor of CEP9
- Precursor of CEP12
Sequence:
MGLLPLVKKLGFIIFLLVSASAFALCSAGRSSILIYSQEDDHPEVVERRIHEHERILRMNSRDYGHSSPKPKLVRPPFKLIPN
Protein: Cathepsin F (CATSF) (EC 3.4.22.41) (Q9UBX1)
Organism: Homo sapiens (Human)
Function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Subcellular location: Lysosome.
Interaction partners:
- Apoptosis regulator Bcl-2
- Bcl-2-like protein 1
- BH3-interacting domain death agonist
- Cathepsin D
- Cysteine protease ATG4B
- Major facilitator superfamily domain-containing protein 8
- GABA type A receptor associated protein like 1
- Ceroid-lipofuscinosis neuronal protein 6
Sequence:
MAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRAVLGLVRGRVRRAGQGSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGRHVLLRKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLPVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVVD
Protein: E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING-type E3 ubiquitin transferase CHFR) (Q810L3)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation. May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress (By similarity).
Subcellular location: Nucleus, PML body {ECO:0000250|UniProtKB:Q96EP1}.
Interaction partners:
- Aprataxin and PNK-like factor
- Poly [ADP-ribose] polymerase 1
Sequence:
MELHGEEQPPPPQEPWGRLLRLGAEEDEPQILLWKREWTIGRRRGCDLSFPSNKLVSGDHCKLTVDEISGEVTLEDTSTNGTVINKLQVVKKQTYPLQSGDIIYLVYRKNEPEHNVAYLYESLSGKQSLTQDSLEANKENMFHVTKDCSGPGQGDDPQVPLLSPMAQTCLEEPQPSTSTSDLLPTASTSSTEPELTSAGQKHSSSSGPGNTSISPKGRSSLVANGELSSLSPVFQDKEASFSLLESKDHEELEPAKKKMKGDGELDTNLQLLVSGQRGNAQTSSEDVKDASVKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVRSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPEYRRQAVQSLPCPVPESELGATLALGGEAPSTSASLPTAAPDYMCPLQGSHAICTCCFQPMPDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLATRGLTWKSVLTESLLALQRGVFMLSDYRITGNTVLCYCCGLRSFRELTYQYRQNIPASELPVTVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN
Protein: Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3) (P60469)
Organism: Mus musculus (Mouse)
Function: May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q91Z79}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:23124857}. Note=Also detected in epididymosome. {ECO:0000250|UniProtKB:Q91Z79}.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase delta
- Receptor-type tyrosine-protein phosphatase F
- Protein diaphanous homolog 1
- Protein unc-13 homolog B
- Receptor-type tyrosine-protein phosphatase S
- Regulating synaptic membrane exocytosis protein 1
- Peripheral plasma membrane protein CASK
- Liprin-beta-1
- ELKS/Rab6-interacting/CAST family member 1
- ARF GTPase-activating protein GIT1
Sequence:
MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQEALNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPVGESNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKDWDRSAPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKTNHVSKEEAGVPRGEGPAVPGDTPPPTPRSARLERMAQALALQAGSPEDGAPPRGSESTPDSLHKAPKRKSIKSSIGRLFGKKEKGRMGPPGRESVSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC
Protein: Homeobox protein SIX2a (Homeobox protein six2.1) (SIX homeobox 2a) (Sine oculis homeobox homolog 2.1) (Six2.1 protein) (Q98TH1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Eyes absent homolog
- E3 ubiquitin-protein ligase ZNRF1
- Rho guanine nucleotide exchange factor
Sequence:
MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNTNSHNPLTSSMNGNKTILGSSDDDKTPSGTPDHTSSSPALLLTSNSGLQSLHGLAPPPGPSAIPVPSVDSVHHHHSLHDTILNPMSSNLVDLGS
Protein: At5g19440 (NAD(P)-binding Rossmann-fold superfamily protein) (Q29Q34)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g56840
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Protein FLOWERING LOCUS T
- Acetyl-CoA carboxylase 1
- Beta-galactosidase 4
- Cytochrome P450 71A23
- Small ribosomal subunit protein eS1z
- Small ribosomal subunit protein eS1y
- Small ribosomal subunit protein eS10z
- Small ribosomal subunit protein eS10x
Sequence:
MANSGEGKVVCVTGASGYIASWLVKFLLSRGYTVKASVRDPSDPKKTQHLVSLEGAKERLHLFKADLLEQGSFDSAIDGCHGVFHTASPFFNDAKDPQAELIDPAVKGTLNVLNSCAKASSVKRVVVTSSMAAVGYNGKPRTPDVTVDETWFSDPELCEASKMWYVLSKTLAEDAAWKLAKEKGLDIVTINPAMVIGPLLQPTLNTSAAAILNLINGAKTFPNLSFGWVNVKDVANAHIQAFEVPSANGRYCLVERVVHHSEIVNILRELYPNLPLPERCVDENPYVPTYQVSKDKTRSLGIDYIPLKVSIKETVESLKEKGFAQF
Protein: Zinc finger protein 843 (Q8N446)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRSLPFALTVESVSARAPTCCSTGRFTQGRQPCKCKACGRGFTQSASLLQHWRVHSDWRETLSLSPVRQDLLWPLQPHQAPASPLGRSHSSAGVRQGFSGQLCCWLTKEHTLAEALRLSPVPAGFWGPVEADRPPANSHRRVCPFCCCSCGDSVNEKTSLSQRVLPHPGEKTCRGGSVESVSLAPSSVAPDSTSGLRPCGSPGSFLQHLPPSTLLPRPPFLYPGPPLSLQPLVPSGLPAVPAVPLGGLEVAQVPPATQPAAQQEGAMGPRSCASAGRDSREAVQAPGYPEPARKASQHRAAGPLGEARARLQRQCRAPPPPSNPHWRGALPVFPVWKASSRRSNLARH
Protein: Pre-mRNA-splicing factor RSE1 (RNA splicing and ER to Golgi transport factor 1) (Spliceosome-associated protein 130) (Q04693)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in G2/M transition (By similarity). Required for pre-mRNA splicing and endoplasmic reticulum (ER) to Golgi secretion pathway. U2 snRNPs associated protein required for the pre-spliceosome assembly. The involvement in ER to Golgi secretion is probably indirect and due to the splicing of the pre-mRNA coding for SAR1, a small GTP-binding protein required for COPII vesicle formation from the ER.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Pre-mRNA-processing ATP-dependent RNA helicase PRP5
- Pre-mRNA-processing factor 19
- U1 small nuclear ribonucleoprotein A
- Pre-mRNA-splicing factor CLF1
- RDS3 complex subunit 10
- Protein HSH49
- Pre-mRNA-splicing factor SNU114
- U2 small nuclear ribonucleoprotein A'
- Cold sensitive U2 snRNA suppressor 1
- U1 small nuclear ribonucleoprotein component SNU71
Sequence:
MWGGGKMAVVSLSPHTAKMRKLFGQASTTMAYDGLKREAERRTRSDHNITMVAKDDELYLYHLTLKKQTNFVHSCIGHFVDLEAGSKREQSQLCVATETHLELYDTADGELKLIAKFQNLFATITSMKSLDLPHSGSRAKASNWPTFLALTSDSGNLSIVQIIMHAGALRLKTLVNQPLTRTTLRRVSPISYMEIDPNGRCIILSSVEQNKLCFLVDYAQKLRISSPLEIIRPHMVTLDMAVVDVNFNNPCFVTLEIDNAATQLSVHLIFYVLELGLNHIVKKADYLVNPSANFVLSLPDLSRYNITTSLSDNNYDADYDTLFNPFVVIGFENHILVKDMNGFFSLKVEIPKRSITNSRHKNVTIISGIVQKLKNDFFVLLQSNHGDLFKLTVSPDTNDRNRPLVQLSYFDTIQNSHQLHIFKNGYLFALSEMNNNFLFQFEKLGVEKNDFSNVLTSKDPNKSLVFEPSIKLQNLSILSQQLNLNPSIKSQIVSDSPLSIATKHFTNNKIITLTNAVNYSNLISTSLPPNATKLWLIPDPATTGDNNTLLFITFPKKTMILQIDNESMEELTPDEATRSAFKLSQDTTIHTCLMGSHSIIQVCTAELRHIVPTGKSRYSNKLTWVPPAGIRIVCATSSKTQLIISLSNYELVYFKIDVSSDSLIELTTHPELDTMPSKVAIVQDTQHADLLAIADNEGMIKIMSLKDQKEDFLTVISLQLVSEKISDMIMVRDSSIGQLNLHVGLENGVYMKFHIGDVDGSFTDIKRRFLGLKPVSLSYLREISVSLNNEEEEEEEEDDDDEKEEEEINSSGAKWMSCVVCHSSSTWVSYTWKNVWTIRQLKDQNMLSCSKFVNADVAINGVCSISSSGRLNIGRVSNFPTLDNWFHVHESSVNKQENGGGDESNEEEEDEMEEEMEMLQISTFRPRTILSFPNNPKSILFIDNHSGKKQCRISLQIDGECLKFGSSDHLYKILDDIDCVSAAIIDFTRQADHLIICAGDKRLLTYKILVNKDKLSFDIELLHQTEIISPIHAMLKFKNFLLTAMGSTIVLYGLGKKQLLRRSVTQTPVSITKIVSMHQWNYERLAVGDIHESVTLFIWDPAGNVFIPYVDDSVKRHVTVLKFLDEATVIGADRYGNAWTLRSPPECEKIMSNHDPSELSNGAIKYPLDVITLQQKLPNTYDCKFKFQLLNHFFVNDIITDFHILDSLSNSDRPGCIYMGLQGTVGCFIPLLSKGNVFMMGNIENIMAEADDTFYLDYESRKKNNNMRKEDDEEESGSVVLQGRHGIEDEIICEGSCSILGRDHQEYRSYYAPVRKVIDGDLCENFLRLSLNEQEFLAKNLKSVQVEDIIQTINEVRTNYM
Protein: Kinesin-like protein (Q9PUU5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Rac GTPase-activating protein 1
- Si:ch1073-416j23.1.
- Epithelial cell-transforming 2
- Uncharacterized protein.
- Kinesin family member 11
- Serine/threonine-protein kinase PLK
- Abnormal spindle-like microcephaly-associated protein
- Centromere-associated protein E
- Centrosomal protein of 55 kDa
- Anillin
Sequence:
MIRQAKGKTPRRPPPKKPSNNQKDPVGVYCRVRPLGAEDEECCIEVISNTTIQLHAPDGLKANRNGEFKETQYSFKKVFGIKTTQRELFEDVAKPLAQDLIHGKNGLLFTYGVTGSGKTHTMTGSPGQGGLLPRSLDMIFNSIGPYQAKRYVFKPDDKNGMEVQNQVDALLDRQKRDSQTSVPKTPNTRRVDPEFADMISPEEACKAEGVDEDSSYSVFVSYIEIYNNYIYDLLEETPFDPIKPKPPQSKILREDQNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTQLNRESSRSHSVFIVKLAQAPLDADGDNVLQDKNQVNVSQLCLVDLAGSERTSRTRAEGNRLREAGNINQSLMTLRTCIEVLRENQMCGTNKMVPYRDSKVTHLFKNYFDGEGKVRMVVCVNPKADDYEETLLVMRFAEMTQEVEVARPVDRPICGFAAGRRQRNQAFKEELTRRLEERGGPVDGDCPTVLNQLLQAFPPLPPCEISGPNDDVTLPRLIEALEKRHKIRQMMIEEYNKTATMLKSVLQEQDGNILSKENVIQEQRGKLGEKDKMLQNQKNEIDRLEKKSKMLEYKIDILQKTTNIYEEDKRSLQNELESREQRLQREMSEKRRIEARMQGMVSDTKLKWEKECERRVNAKQLEMQNKLWVKDEKLKQLKAIVTEGKTENRQPQRPSREKDKVPPKRSASPSPAPTGPPVRPLHRRSHSAGGERWVDHKPTTNVDLDTVMQPNIPNAIKVNAPNEKALSKCDKYVLTHQEVASDGEIQTKLIKGEVFKTRGGGQSVQFTDIETLKQETPVAASRKRRSSESGPDSEPMEGNWTDVETRCSVAVEMRAGSNLGPGYQHHGYTKRRKP
Protein: Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha) (Q8N5S9)
Organism: Homo sapiens (Human)
Function: Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Calmodulin-1
- Calmodulin-like protein 3
- Calmodulin-like protein 5
- Calmodulin-like protein 6
- Calmodulin-like protein 4
- Calmodulin-1
- Calcium/calmodulin-dependent protein kinase type IV
- Calcium/calmodulin-dependent protein kinase kinase 2
- Calcium/calmodulin-dependent protein kinase type 1
Sequence:
MEGGPAVCCQDPRAELVERVAAIDVTHLEEADGGPEPTRNGVDPPPRARAASVIPGSTSRLLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRRPTIESHHVAISDAEDCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMSAPGNLLVKEGFGEGGKSPELPGVQEDEAAS
Protein: Receptor-like protein 12 (AtRLP12) (Q9C9H7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the perception of CLV3 and CLV3-like peptides, that act as extracellular signals regulating meristems maintenance.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Subtilisin-like protease SBT3.1
- ATPase family AAA domain-containing protein At1g05910
- Putative G-type lectin S-receptor-like serine/threonine-protein kinase At1g61610
Sequence:
MMIRSHRHWVFSSRIIIFLSLLVHSLASSSPHFCRDDQRDALLEFRGEFPINASWHIMNQWRGPWNKSTDCCLWNGVTCNDKSGQVISLDIPNTFLNNYLKTNSSLFKLQYLRHLDLTNCNLYGEIPSSLGNLSHLTLVNLYFNKFVGEIPASIGNLNQLRHLILANNVLTGEIPSSLGNLSRLVNLELFSNRLVGKIPDSIGDLKQLRNLSLASNNLIGEIPSSLGNLSNLVHLVLTHNQLVGEVPASIGNLIELRVMSFENNSLSGNIPISFANLTKLSIFVLSSNNFTSTFPFDMSIFHNLEYFDVSYNSFSGPFPKSLLLIPSLESIYLQENQFTGPIEFANTSSSTKLQDLILGRNRLHGPIPESISRLLNLEELDISHNNFTGAIPPTISKLVNLLHLDLSKNNLEGEVPACLWRLNTMVLSHNSFSSFENTSQEEALIEELDLNSNSFQGPIPYMICKLSSLGFLDLSNNLFSGSIPSCIRNFSGSIKELNLGDNNFSGTLPDIFSKATELVSLDVSHNQLEGKFPKSLINCKALELVNVESNKIKDIFPSWLESLPSLHVLNLRSNKFYGPLYHRHASIGFQSLRIIDISHNNFSGTLPPYYFSNWKDMTTLTEEMDQYMTEFWRYADSYYHEMEMVNKGVDMSFERIRRDFRAIDFSGNKINGNIPESLGYLKELRVLNLSGNAFTSVIPRFLANLTKLETLDISRNKLSGQIPQDLAALSFLSYMNFSHNLLQGPVPRGTQFQRQKCSSFLDNPGLYGLEDICRDTGALNPTSQLPEDLSEAEENMFNWVAAAIAYGPGVLCGLVIGHFYTSHNHEWFTEKFGRKQHKALTSVKCSL
Protein: Putative disease resistance protein At4g11170 (EC 3.2.2.6) (O82500)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cell wall RBR3-like protein
- Glutamate receptor 2.9
- Alpha/beta-Hydrolases superfamily protein
- Glutamate receptor 1.3
- Jacalin-related lectin 44
- Protein RECOGNITION OF PERONOSPORA PARASITICA 7
- Putative germin-like protein subfamily 1 member 9
- Probable disease resistance protein At5g45510
- Glutathione S-transferase family protein
- Germin-like protein subfamily 1 member 14
Sequence:
MASSSSNSWRYDVFPSFRGEDVRNNFLSHLLKEFESKGIVTFRDDHIKRSHTIGHELRAAIRESKISVVLFSENYASSSWCLDELIEIMKCKEEQGLKVMPVFYKVDPSDIRKQTGKFGMSFLETCCGKTEERQHNWRRALTDAANILGDHPQNWDNEAYKITTISKDVLEKLNATPSRDFNDLVGMEAHIAKMESLLCLESQGVRIVGIWGPAGVGKTTIARALYNQYHENFNLSIFMENVRESYGEAGLDDYGLKLHLQQRFLSKLLDQKDLRVRHLGAIEERLKSQKVLIILDDVDNIEQLKALAKENQWFGNKSRIVVTTQNKQLLVSHDINHMYQVAYPSKQEALTIFCQHAFKQSSPSDDLKHLAIEFTTLAGHLPLALRVLGSFMRGKGKEEWEFSLPTLKSRLDGEVEKVLKVGYDGLHDHEKDLFLHIACIFSGQHENYLKQMIIANNDTYVSFGLQVLADKSLIQKFENGRIEMHSLLRQLGKEVVRKQSIYEPGKRQFLMNAKETCGVLSNNTGTGTVLGISLDMCEIKEELYISEKTFEEMRNLVYLKFYMSSPIDDKMKVKLQLPEEGLSYLPQLRLLHWDAYPLEFFPSSFRPECLVELNMSHSKLKKLWSGVQPLRNLRTMNLNSSRNLEILPNLMEATKLNRLDLGWCESLVELPSSIKNLQHLILLEMSCCKKLEIIPTNINLPSLEVLHFRYCTRLQTFPEISTNIRLLNLIGTAITEVPPSVKYWSKIDEICMERAKVKRLVHVPYVLEKLCLRENKELETIPRYLKYLPRLQMIDISYCINIISLPKLPGSVSALTAVNCESLQILHGHFRNKSIHLNFINCLKLGQRAQEKIHRSVYIHQSSYIADVLPGEHVPAYFSYRSTGSSIMIHSNKVDLSKFNRFKVCLVLGAGKRFEGCDIKFYKQFFCKPREYYVPKHLDSPLLKSDHLCMCEFELMPPHPPTEWELLHPNEFLEVSFESRGGLYKCEVKECGLQFLEPHETSEFRYLSPHLYLGGSWIGNSSSSIEEIIHVDQEESSSDSEEIIYADQEESSSGIEEIIHAEREGTNRRKSVMRWIKVGARKMGLSLECLKPWTR
Protein: Fibroblast growth factor 14 (FGF-14) (Q8R5L7)
Organism: Rattus norvegicus (Rat)
Function: Probably involved in nervous system development and function.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Sodium channel protein type 2 subunit alpha
- Sodium channel protein type 8 subunit alpha
- C-Jun-amino-terminal kinase-interacting protein 2
- Fibroblast growth factor receptor 1
- Sodium channel protein type 5 subunit alpha
Sequence:
MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQVMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKAGVTPSKSTSASAIMNGGKPVNKCKTT
Protein: RE67391p (Q8SYD4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
Sequence:
MLKEEGVNAFYKGLVPLWMRQIPYTMMKFACFERTVELLYKYVVPKPRADCTKGEQLIVTFAAGYIAGVFCAVVSHPADVVVSKLNQAKGASAISVAKSLGFSGMWNGLTPRIIMIGTLTALQWFIYDGVKVALGIPRPPPPEMPASLKAKQH
Protein: Sos1 protein (Q497A5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
AFSQSAIKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECMKQAITALLNVQSGMEKICSKNLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEHMRLPSADVYRFAEPDSEENILFEENVQPKAGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLNLLIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDVDLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQNSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKKK
Protein: Prefoldin subunit 4 (Genes involved in microtubule biogenesis protein 3) (Gim complex subunit 3) (GimC subunit 3) (P53900)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Interaction partners:
- Prefoldin subunit 5
- Prefoldin subunit 3
- Prefoldin subunit 1
- Prefoldin subunit 6
- Prefoldin subunit 2
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit eta
Sequence:
MELLPQGQRNNTQVTFEDQQKINEFSKLIMRKDAIAQELSLQREEKEYLDDVSLEIELIDEDEPVQYKVGDLFIFMKQSKVTAQLEKDAERLDNKIETLEDKQRDIDSRLDALKAILYAKFGDNINLER
Protein: S-type anion channel SLAH3 (SLAC1-homolog protein 3) (Q9FLV9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis. Binds to the highly selective inward-rectifying potassium channel KAT1 and inhibits its activity. Functions as an essential negative regulator of inward potassium channels in guard cells. Essential for the efficient stomatal closure and opening in guard cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14506206, ECO:0000269|PubMed:18305482}; Multi-pass membrane protein {ECO:0000269|PubMed:14506206, ECO:0000269|PubMed:18305482}.
Interaction partners:
- Calcium-dependent protein kinase 21
- Aluminum-activated malate transporter 12
- Calcineurin B-like protein 1
- Calcium-dependent protein kinase 20
- Serine/threonine-protein kinase SRK2E
- Potassium channel GORK channel)
- Calcium-dependent protein kinase 23
- Calcium-dependent protein kinase 6
- Calcium-dependent protein kinase 2
- Calcium-dependent protein kinase 3
Sequence:
MEEKPNYVIQVEEELPTLLRKATTEEMVGFDNYKENGHPFPHSISRFHPSHASTTTLNGQETSRSIDTMEAHHHNYNETTPWTHQRKPSISMPTSPNVLMISDPTTSLSSENHKNSGSTGKSVKFLSQPMTKVSSLYIESGNGDDDRRQSHDNHHHHLHRQHQSGHHQNQNQAANKLKDNRYNSFKTWSGKLERQFTRKPASVEPEAPNRNNQNLNTNEAMPVDRYYDALEGPELETLRPQEEIVLPNDKKWPFLLRYPISTFGMCLGVSSQAIMWKTLATAEPTKFLHVPLWINQGLWFISVALILTIATIYLLKIILFFEAVRREYYHPIRINFFFAPFISLLFLALGVPPSIITDLPHFLWYLLMFPFICLELKIYGQWMSGGQRRLSRVANPTNHLSVVGNFVGALLGASMGLREGPIFFYAVGMAHYLVLFVTLYQRLPTNETLPKDLHPVFFLFVAAPSVASMAWAKVTGSFDYGSKVCYFIAIFLYFSLAVRINFFRGIKFSLSWWAYTFPMTGAAIATIRYATVVKSTMTQIMCVVLCAIATLVVFALLVTTIIHAFVLRDLFPNDLAIAISNRPRPKQNSQHRWLDQLRNVSSENIENYLKFTDSDSSQSNDVEACNGKTQESDSS
Protein: PHD finger protein 10 (S5FMB0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGSGDSSRSCETSSQDLGFSYYPAENLIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYLRELNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYSQMQQQNTQKVEASKVPEYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHVIQVPQGKYKVLPTERTKVSSYPVALIPGQFQEYYKRYSPDELRYLPLNTALYEPPLDPELPALDSDGDSDDGEDGRGDEKRKNKGTSDSSSGNVSEGESPPDSQEDSFQGRQKSKDKAATPRKDGPKRSVLSKSVPGYKPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQCMECKTCIICGQPHHEEEMMFCDMCDRGYHTFCVGLGAIPSGRWICDCCQRAPPTPRKVGRRGKNSKEG
Protein: Acid-sensing ion channel 1C (ASIC1-C) (Acid-sensing ion channel 1.3-C) (Amiloride-sensitive cation channel 2-C, neuronal-C) (ZASIC1.3) (Q708S6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14970195}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q1XA76}. Postsynaptic cell membrane {ECO:0000305|PubMed:14970195}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q6NXK8}.
Interaction partners:
- Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
Sequence:
MTAMKGDSEDSIESMRPSNLQVFANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLLMYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKITKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECFPLNFTTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAPMDSEYFSTYSITACRIDCETRYLLENCNCRMVHMPGTSTVCTPEQYKDCADPALDFLVEKDNDYCVCDTPCNMTRYGKELSMVKIPSKASAKYLAKKFNKTEQYITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVLKDKILGSVLRKRRPHRSASDNLVIVSLHDFKISSVFLLASYMCFVCYIVLLNAACVYLPFVVGSNSGK