wanglab/gogpt-training-data huggingface dataset:
Protein: Protein phosphatase 2C-like, putative (EC 3.1.3.16) (Q38BA8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGETLSKPVTEKHTSTFETSHIHVGCCAMQGWRKTMEDAHVAQLNLGGNKHHTFIGVFDGHNGNKIAKYCREHLLDELMLTPEYRSGSYDEAFKKAFGAIDSNLSKMSMLRSEGGTAAICVMLTQNEVICANAGDSRAVLYRGTRAIPLSIDHKPSAPGEKERILRAGGTVQSHRVDGNLAVSRAIGDFDYKENSELSWEEQIVTALPDVTRIDIKEEDAFVVVACDGVWDVLSNDDCCQLIHQSFKDTEDDIGLVCEAVLDRCLAPCIQGTGCDNMTIVIARFKPAFFCSER
Protein: Protein SIP4 (P46954)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Interacts with the SNF1 protein kinase.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Carbon catabolite-derepressing protein kinase
- SNF1 protein kinase subunit beta-3
- Regulatory protein MIG1
- RNA polymerase I-specific transcription initiation factor RRN11
- Truncated non-functional calcium-binding mitochondrial carrier SAL1-1
- Monoglyceride lipase
- SNF1 protein kinase subunit beta-2
- Acyl carrier protein, mitochondrial
- SNF1 protein kinase subunit beta-1
- 5'-AMP-activated protein kinase subunit gamma
Sequence:
MAKRKYGRSYSLDDTDSCSNKVLIVPTGQSSSNAITDFSVRKAHACDRCRLKKIKCDGLKPNCSNCAKIDFPCKTSDKLSRRGLPKGYTELLEKEVVRLTNMNASSSANANSNLPFINDTFYCFDNYNTQSENQRFLGHLTWNILTNTFPTQKAVVFTDDRNNIDLQLQLLTNFLNLNGDFNHLPNFLLLKYDYNLQFLKNLLSVIIKDFFKRQNSLLLLLYPTNLWKNLLLDKINSTAMTGEPITLLALLYIIQFTWSCFDDFKLFKVTKLIVSLTTNSKLDLKVLQLVNLSIFYFMGASVDSCKSKSSLTEHSNVNSVIWTNDLLNLNFTNILNMGLYINPKNLIPISGNNNNNKSNEEDDRIVTFWCFQFLSSWWSLIQGLPKSNFLTEEFQPKSISVLEIPRLKPFEILLNFIIYSLDGCNLLNISSLNVSDPNFQFFQNELESFKKNLLLWNLYHNLSDHDNFRFLTSSSNKKLTTNLLLKNLTGLNHKLNQPDFVEIQLTLFYLSLKLMTLKEGDQDLKKEDISLEILSLYFLILTDDSNNDDNQQLQPQQLNLYHFTPFNSIDIIDLCLNNLNNWSLSLKYESGQNQPHSSKIKFEKFQNFLNHWCPIWYYDEFSTNPFLQILKINFKLLPFETIHYSQEEQRLLISLNKLRYLDAVSSFNSSSVKSNFASKVNTQLNLLQHSSSNSNFLDASPYDFNKIFMNNFENYDYETDEGYAEDDDEEDSDSDNSLPLEIPFKKSKNKCKNRNKELSQRLSLFENRDSNSVDFNTDTNLNLNPDSPSVTSSKKKYLDHIILDNRDIVSNHDSSKQKFKIQNILNSTF
Protein: Transcription factor Sp8 (Q8BMJ8)
Organism: Mus musculus (Mouse)
Function: Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeobox protein EMX2
Sequence:
MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSGSCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSGAHSQDSSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAADVGSAGASSWWDVGAGWIDVQNPNGAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGSSMLSAGPAAQLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGSAGSGGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
Protein: CARD domain-containing protein (Q5F3W0)
Organism: Gallus gallus (Chicken)
Interaction partners:
- Paracaspase
- Protein kinase C
- TNF receptor-associated factor
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Mitogen-activated protein kinase kinase kinase 7.
- Paracaspase 2
- Tyrosine-protein kinase BTK
- 3-phosphoinositide-dependent protein kinase 1
- B-cell lymphoma/leukemia 10
- B-cell antigen receptor complex-associated protein beta chain
Sequence:
MSTQGGEPEMDDCLETLKDEEEALWENVECNRHMLSRYINPAKLTPYLRQCKVIDEQDEDEVLNSLMLPSKINRAGRLLDILHTKGQRGYVVFLESLEFYYPELYKLVTGKEPTRRFSTIVVEEGHEGLTHFLMNEIIKLQQQVKTKDMQRCDLLAKSRQLEDERKQLKLNKIELMTFQERYNKMKEERNNYNDELVKVKDENYNLAMRYAQLSDEKSMAVMRSRDLQLEIDQLKHRLNKVEEECKLERNQSLKLKNDIENRPKKEQMLELERENEMMKTKIQELQSIIQADKRSLPDSDKAILDILEHDRKEALEDRHELVNKIFNLQEEIRHVEDLRDKYLEEKEDLELKCSTLGKDCEMYKHRMNTVMIQLEEVEKERDQAFRSRDEAQTQYSHCLIEKDKYRKQIRELEERNDELRIEMVRKEACIVNLECKLRRLSKDNNCHDQSLPRNLPITIISQTFGNSSPKANGQEADDSSTSEDSPEDNKFFLPDQARLKRRVNLKGIQINPRAKSPVSMNRTSEFQAVRAQDEDGANASNGRTDTSSSNSVSISNSISSCEVSKIQTLRNRNDSIMSTTPEPPGNDSIVRRCKEDAPPCSMVEEDNDSFGFDALELDDDSHDRHSHGAPSVHSSSSSHQSEGLDAYDLEHVNSIFRKFSLERPFRPSVTSVGRIRSSCHTIQRITLNGDTLNSEITLIGGNDKGSFVSSVVSGSLAEKAGLREGHQLLLLEGCIKGENQSVPLDTCTKEEVHWTIQRCHGPVTLQYKSNHEGYRKLLSELEDGLIASGDSFHIRLNLNISSQLDCCSLSVKCDEIVHILDTMYQGTCGGCDWLCARVDPFTDKDLERGTIPSYSRAQQLLLVKLQRLMHRGSKDETESSHNTLRALRNTLQPEEPAPQSDPKTSPRLSRASFLLGQILQFVSRSENKYKRMNSNERVRIVTGWPSGLARTASEAKKPFPDKLEDLDSKSEINKRLIPYSLVRPIHCERRRPVLFTPTMLAKSLVQKLLNSGGALEFDICKPDIVTKEEFLRRQRMETIIFSREKNLSTYECIVPANIEAVSAKNKHCLLEAGISCTKDLIKAKIYPIVLFIRVSEKNIKRFRKLLPKPEAEDEFLRMCRLKEKELEELPCLYASVEADAWSSIEDLIRTIKDKIGEEQRKTIWIDEDQL
Protein: Protein brother (Q24039)
Organism: Drosophila melanogaster (Fruit fly)
Function: Regulates the DNA-binding properties of Runt.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Cullin-5
- Elongin-C
- Segmentation protein Runt
- Elongin-B
- Early boundary activity protein 1
- LD28817p
- Early boundary activity protein 3
Sequence:
MHHHQNLGDAAAMNGMIPPYEAMAMYEQPKPRFIFKMPRVVPDQRSKFDSDELFRRLSRESEVRYTGYRERAMEERRMRFVNDCRKGYAEISMVASGTNLQLYFNANHNPYAQEQDCDFERERGKVHLRSSFIMNGVCVRFRGWVDLDRLDGAACLEFDEQRAQQEDAQLQEQIQSYNQRMAESRRIYHTPQTPPEDHHHRGGPGLPRGPMGW
Protein: Small ribosomal subunit protein uS11 (40S ribosomal protein S14) (P13471)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62263}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62263}.
Interaction partners:
- Small ribosomal subunit protein uS7
- Ubiquitin-like protein FUBI
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein uS19
Sequence:
MAPRKGKDKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL
Protein: WEB family protein At5g55860 (Q9LVQ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- WEB family protein At5g16730
- At1g10140
- B3 domain-containing protein REM1
- Syntaxin-122
- Plasma membrane-associated cation-binding protein 1
Sequence:
MVAKKGRRDSSDSSPIVEVGEIDTSAPFQSVKDAVNLFGEAAFSAEKPVFRKPNPQSAEKVLVKQTELHLAQKELNKLKEQLKNAETIREQALSELEWSKRTVDELTRKLEAVNESRDSANKATEAAKSLIEEAKPGNVSVASSSDAQTRDMEEYGEVCKELDTAKQELRKIRQVSNEILETKTVALSKVEEAKKVSKVHSEKIELLRKEIAAVNESVEQTKLACSQARKEQSEIFAEKEIQQKSYKAGMEESAKKSLALKNEFDPEFAKKLEVQLTETYNEIDELQKQMETAKASDIDSVNGVSLELNEAKGLFEKLVEEEKSLQELVESLKAELKNVKMEHDEVEAKEAEIESVAGDLHLKLSRSKSELEQCVTEESKAKAALEDMMLTINQISSETEAARREAEGMRNKAKELMKEAESAHLALEDSELHLRVALDEAEEAKAAETKALEQIKSMSEKTNAARNSTSSESGSQSITLSQEEFKSLSKRAEVFDKLAEMKVAAALAQVEAVRASENETLKKLETTQEEIKKLKTATEEALKKAAMADAAKKAVEGELRRWRERDQKKAEEAATRILAEAEMKMASESSPQQHYKAPKQKPVNNKLEKTKTSVVSKKVLMPNLSGIFNRKKNQVEWGSPSYLPGEKPF
Protein: Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192) (Q15776)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
Interaction partners:
- Zinc finger protein 396
- Zinc finger protein 397
- Zinc finger and SCAN domain-containing protein 32
- Zinc finger protein with KRAB and SCAN domains 4
- Zinc finger protein 444
- Zinc finger and SCAN domain-containing protein 20
- PiggyBac transposable element-derived protein 1
Sequence:
MAEESRKPSAPSPPDQTPEEDLVIVKVEEDHGWDQESSLHESNPLGQEVFRLRFRQLRYQETLGPREALIQLRALCHQWLRPDLNTKEQILELLVLEQFLTILPEELQTLVKEHQLENGEEVVTLLEDLERQIDILGRPVSARVHGHRVLWEEVVHSASAPEPPNTQLQSEATQHKSPVPQESQERAMSTSQSPTRSQKGSSGDQEMTATLLTAGFQTLEKIEDMAVSLIREEWLLDPSQKDLCRDNRPENFRNMFSLGGETRSENRELASKQVISTGIQPHGETAAKCNGDVIRGLEHEEARDLLGRLERQRGNPTQERRHKCDECGKSFAQSSGLVRHWRIHTGEKPYQCNVCGKAFSYRSALLSHQDIHNKVKRYHCKECGKAFSQNTGLILHQRIHTGEKPYQCNQCGKAFSQSAGLILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTGEKPYECDECGKTFRRSSHLIGHQRSHTGEKPYKCNECGRAFSQKSGLIEHQRIHTGERPYKCKECGKAFNGNTGLIQHLRIHTGEKPYQCNECGKAFIQRSSLIRHQRIHSGEKSESISV
Protein: WD_REPEATS_REGION domain-containing protein (Q22059)
Organism: Caenorhabditis elegans
Interaction partners:
- Cullin-4
- DNA damage-binding protein 1
- CDT1 Geminin-binding domain-containing protein
- RING-box protein 1
- Proliferating cell nuclear antigen
- Cell division control protein
- Minichromosome loss protein Mcl1 middle region domain-containing protein
- Protein MCM10 homolog
- Exonuclease 1
- Origin recognition complex subunit 1
Sequence:
MDFLHSTKARKRYLRYPSSIYEELESKHYSMPAGETDDHDTWVTARFSPHLNQEHILYMGDDPGNIGIFDVRKFQDRSVPLEERQLYFFPAHDGAIMDVVGVPQKESQIVSISGDSTIRCWDLNQSTLDRKSQVFFGHEGSVRSICFAPDDPNVFVTGGRDFQVKIWDMRVSTVKKMEEDCRMATITYKTAHPKPSKVLTSGTPKSKAKAKTIEGYKVTSVLFLDEHHVASASENADSGIRVWDIRKPTRNGEGQPARILKVPTSNKKSYGVTCLTLDRFGNRLFASCTDSSIFEYSVPSESVSPINSYTGATIHNFYTQVACSPVSDVIACGSEDSRAVVWDLQDQYNYMNDRKLPDDIDKRRTKLPRFSCDGHLKQVLNVGWSSRGTYFMSCDEGGVRIWSEPRNRCTWKLNDEDDTSYPTTSQELGLSYEKIKKFELKESDEAMSCFDSISLSPRQRADSSGLSGSPQKNRGSKRPIFESPLKSICTNSPKPLRLNRSPRAKMSKLSFSPPSPLQPTNSNNQDLVGYRTPRQIRNKKKKNNPFYNEHPTEGLPNFVYDTFVKKLIGESSKSDIEDSGKSLSKTGQKRIEDWWQTKGENVATVTRARLPSVSEFGESACSKVITEDERIALHSPRKLVLKSSSTQSPCPSNSKPKPIPMTPRKPMDKRPTSRNLLHYFKK
Protein: PDGF- and VEGF-receptor related, isoform G (EC 2.7.10.1) (RE12971p) (B6IDV6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MAMLPRLILLPLLLILRISWSDAVPLQQFSPDPDDSIENCGGENGAPLMTPCKSAIILDAQTSTTLKCEDDEPMSWWTSQSQYVHVKSFDNTEDPARPFGTSLHLIEVTADYVAAYYCVKTSKFSQIAKEEQSDEAMIELVNQGYASSIYVYVNDPDTKLVDSHNVVTARQYTDVVIPCKPAMPDTEVLLETSNGEMHSSKSVGRYDPQRGFTIEIRSIVDGGDYYCRPNPPFPHNEEEMTSIEVRFIEDGKPLPKPVIRSSVEHHVFTDTNFTLDCEQSAYVESVYGMEWFTPSRDENRIFASQSRTDPKTRNSTHQTGRSTLTVLNAQPSDTGLYKCVTTDNSNQNVQRATYRIKVLKQNESYLNVGEPSGHYNVQEYANRTIQMTANFEGFPTPSFSWFKPDGTEVRQSENNFKILSTELSTMLQVLNAQLQDSGTYVLRGSNSFGVVQREYNVSVMDAPALKMSDAYVQVGSVARLECTVRSYPPAIVTFFFRPCSLEPQWPTCSVLNQNFSLPSEQEKYQFQTRPRPGKLSVERIYEVSFLPTEPGILTCIAQNIIDGKERRTLTKAHVLLGNISENMTIYGFDKDHKIAKEDNVNFTCEALAYHFDGNLKWFINGEDLKESDSVHIETSHTKYSYKSTVHITTISDRDRGTYECRAYHNDKDAVYSSREIDLYVHDPSAPQWTNGGQEGHSKIKRKLSQTLELECASTAVPVAIVRWFKDDKEVTESKLRHIIEKESKLLITHLYPGDEGVYKCVVENRLDRIERSFTVVISDLPGISMAWVWFGVILFLILIGLCVFLAVRYQKEHKRHLALKAAGLANFEEGAVGHINPDLTLDEQAELLPYNREFEFPRENLKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVVRALVSELKIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPDTDHIDPSIMTQRMSDNYELHRNSDNDPRSGTRAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTVDLISWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELYEIMLECWRKNPESRPLFAELEKRFANMLGEDVASHYLDLNNPYMQSNIEYMKKQSTDYLALMGSPDELAPAAPRYVNGHIVPDIRIEELPDDYMEMSRDSDPDACTAIFSPTRLEGESSDFPDFSSETTFNFPGARQSPTLSNNLNSGSSKPLRKKNGMPTVDVADQAPEEIPMLHRSSTGSDGSPEQGRRFNQALKQQYVTPTPSPRHHVETKLNGEPSENYVNMKPPRKNIPGKTTTGGGGAAAGASTEAFSNPSYQPLSTVNEKEQRRY
Protein: Holin (KMV44) (Pinholin) (Q7Y2C1)
Organism: Pseudomonas phage phiKMV
Function: Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of nanometer-scale pores (pinholes) causing host cell membrane depolarization and endolysin refolding and release into the periplasmic space. Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm and breaks down the peptidoglycan layer. Determines the precise timing of host cell lysis. Participates with the SAR-endolysin and the U-spanin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell.
Subcellular location: Host cell inner membrane {ECO:0000250|UniProtKB:P03705}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MMLDTATEAGKGTLAVTGVGIAVYSPYEIASLCAAVLTALYVGAQLITLLPKMLDSIAELRRRFKK
Protein: Hydroxyproline O-galactosyltransferase HPGT1 (EC 2.4.1.-) (Beta-1,3-galactosyltransferase 11) (Q94F27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses hydroxyproline O-galactosyltransferase activity. Transfers galactose from UDP-galactose to hydroxyproline residues in the arabinogalactan proteins (AGPs). Is specific for AGPs containing non-contiguous peptidyl hydroxyproline residues. The addition of galactose onto the peptidyl hydroxyproline residues in AGP core proteins represents the first committed step in arabinogalactan polysaccharide addition. AGP glycans play essential roles in both vegetative and reproductive plant growth.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:25600942}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Hydroxyproline O-galactosyltransferase GALT4
- Hydroxyproline O-galactosyltransferase GALT5
- Hydroxyproline O-galactosyltransferase GALT2
- Beta-1,6-galactosyltransferase GALT29A
- Inositol phosphorylceramide glucuronosyltransferase 1
Sequence:
MARKGSSIRLSSSRISTLLLFMFATFASFYVAGRLWQESQTRVHLINELDRVTGQGKSAISVDDTLKIIACREQKKTLAALEMELSSARQEGFVSKSPKLADGTETKKRPLVVIGIMTSLGNKKKRDAVRQAWMGTGASLKKLESEKGVIARFVIGRSANKGDSMDKSIDTENSQTDDFIILDDVVEAPEEASKKVKLFFAYAADRWDAQFYAKAIDNIYVNIDALGTTLAAHLENPRAYIGCMKSGEVFSEPNHKWYEPEWWKFGDKKAYFRHAYGEMYVITHALARFVSINRDILHSYAHDDVSTGSWFVGLDVKHVDEGKFCCSAWSSEAICAGV
Protein: Variant surface glycoprotein (VSG), putative (Q4GY52)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MTLPQQVLIGIMVLSTSRRAQTEKPADDAACANLCACIARTHKRLNLYEITYASAASQQRSNHENYNKLIVAATVGDANLKRKLVPVIAAGGEILEECADLPDKLQKQTKDLTEGVNQLTRSWKIMDAMTATSRRFKVTATGGTPFAQLPTPSALAARDDKPCPSLTDSEDLLQIDKATEAKQPALPEQAYALKVVYKCTHNGAASCHSTQIAENGFVELELTGGPAQNQGTAASRLGTSLENGINLEVTPLKITGDLLKKVNANFTAAKQLLQNQSCSKDLREYSALSGTQVFGKLATKALLRLYDKESIDTGDQQAQAATKDAYGQTGEKLATNVWQLVDDIKVPVTGDGKEQNTALNSVTTMRQLGDSVARLLLKELKSEEEKETKNKNAEEEQNKECSDKNGTDCTRICVMVEGVCTPKKKGEDENKEKTGTTNTTGSNSFVIKKAPLWLAFFILACDF
Protein: Notchless protein homolog (Q9FLX9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for female gametophyte development.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:P25382}.
Interaction partners:
- Protein ROOT INITIATION DEFECTIVE 3
- Ribosome assembly factor mrt4
- Nuclear/nucleolar GTPase 2
- Ribosome production factor 2 homolog
- Probable ribosome biogenesis protein RLP24
- Ribosome biogenesis protein WDR12 homolog
- Expressed protein
- AT5g04600/T32M21_200
- Pescadillo homolog
- Guanine nucleotide-binding protein-like NSN1
Sequence:
MTMMDTDEGKTVMCLLTDPEGTHLGSAMYIPQKAGPLQLTQLVNRFLDNEEMLPYSFYVSDEELLVPVGTYLEKNKVSVEKVLTIVYQQQAVFRIRPVNRCSQTIAGHAEAVLCVSFSPDGKQLASGSGDTTVRLWDLYTETPLFTCKGHKNWVLTVAWSPDGKHLVSGSKSGEICCWNPKKGELEGSPLTGHKKWITGISWEPVHLSSPCRRFVTSSKDGDARIWDITLKKSIICLSGHTLAVTCVKWGGDGIIYTGSQDCTIKMWETTQGKLIRELKGHGHWINSLALSTEYVLRTGAFDHTGRQYPPNEEKQKALERYNKTKGDSPERLVSGSDDFTMFLWEPSVSKQPKKRLTGHQQLVNHVYFSPDGKWIASASFDKSVRLWNGITGQFVTVFRGHVGPVYQVSWSADSRLLLSGSKDSTLKIWEIRTKKLKQDLPGHADEVFAVDWSPDGEKVVSGGKDRVLKLWKG
Protein: Uncharacterized protein (Q582C0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPLLLRLCLRIVDPDGAEMMMWLSYSVISTTTASDVIRFAQRTVCERLGASLAAPVGELTLCIRDIFMRFVAVGTLASSKNEVPITTMRFFEELLRANRENRSSSSMCMGGDGAWQKFIVIQGALAPTKVLRHLDVPKSAGTTHPSCRCQIVEVPSELGREPLSVDDPLGTSRNSLVSYTNETAFASPKLEVNDNDDSVVINSSASEMRDSMSVDVRHVSVEGEQHTITLRAADLQSLETALLKCCEDLGPKAGYELEPSRMRLMYSTEENTQSFPVETDMVLKQTLENPNVTCLSLVERSQVSNSASDTATLSERTGLARTRREPIDDSSHEPFADVTPMELRRNACVIPGATPKKPLILKHVDTVPPLPAFSSLNDLSPVENSFRPMKANGKRRTSDLVKGDITGSNSELASFHRDMDEALGYYYRIVEENNRSIGMLQHQVSSLTNELKGYNNAEQDCKSLEKILERLRMNVGRGESRQKGLLQELDEL
Protein: Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (Q57ZK2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGKENMKGGKNTGSSADGGKKGKDTSGGSGYTKVKVRHILCEKLSRALEALEKIKAGESFANVARDYSEDKARSGGDLGWVTRGAMVGEFSEKAFALPKGGMTQEPVKTKFGYHIIFVEDKQ
Protein: Microspherule protein 1 (58 kDa microspherule protein) (Q99L90)
Organism: Mus musculus (Mouse)
Function: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA. Binds to RNA homomer poly(G) and poly(U).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96EZ8}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q96EZ8}. Cytoplasm {ECO:0000250|UniProtKB:Q96EZ8}. Note=In microspherules in the nucleolus. {ECO:0000250|UniProtKB:Q96EZ8}.
Interaction partners:
- KAT8 regulatory NSL complex subunit 3
- KAT8 regulatory NSL complex subunit 2
- PHD finger protein 20
- WD repeat-containing protein 5
- KAT8 regulatory NSL complex subunit 1
- Host cell factor 1
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- Histone acetyltransferase KAT8
- INO80 complex subunit C
- Nuclear factor related to kappa-B-binding protein
Sequence:
MDKDSQGLLDSSLMASGTASRSEDEESLAGQKRASSQALGTIPKRRSSSRFIKRKKFDDELVESSLAKSSTRVKGAGGVESGRCSGSEPSSSEKKKVSKAPSTPVPPSPAPTPGLTKRVKKSKQPLQVTKDLGRWKPADDLLLINAVLQTNDLTSVHLGVKFSCRFTLREVQERWYALLYDPVISKLACQAMRQLHPEAIAAIQSKALFSKAEEQLLSKVGSSSQPTLETFQDLLHTHPDAFYLARTAKALQAHWQLMKQYYLLEDQTVQPLPKGDQVLNFSDAEDLIDDSKLKDMRDEVLEHELTVADRRQKREIRQLEQELHKWQVLVDSITGMGSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNGDFFIANEGRRPIYIDGRPVLCGSKWRLSNNSVVEIASLRFVFLINQDLIALIRAEAAKITPQ
Protein: Transmembrane protein 205 (Q6UW68)
Organism: Homo sapiens (Human)
Function: In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
Subcellular location: Membrane {ECO:0000269|PubMed:20589834}; Multi-pass membrane protein {ECO:0000269|PubMed:20589834}. Note=Located on cell surface microvilli. In cancer cells, transition in subcellular location from cell surface to intracellular regions correlates the progression of cisplatin resistance.
Interaction partners:
Sequence:
MEEGGNLGGLIKMVHLLVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHAWAQLTFWEASQLYLLFLSLTLATVNARWLEPRTTAAMWALQTVEKERGLGGEVPGSHQGPDPYRQLREKDPKYSALRQNFFRYHGLSSLCNLGCVLSNGLCLAGLALEIRSL
Protein: Pericentrin-like protein, isoform G (M9PCJ5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
Sequence:
MGKLHITSLLRPHGASVSYKAIEAATLEELPATSVATATSTAATSRATGGAAATCVDVEFIPTLNIIFEKPTSSSEQLQCAEKSEHVAGGVSDKEPADDCDSDNDSTRTYIISRSSWTGVTSSSSTPYAVTSTDTAELLRRQNNLSLTEEDQSVSSFSIEQPTSSITIEMADQRTTTTTTTTATTATTPSSANILATTATTTTTTSSSIEEEIEEAIEISEVEEQLNTPLESLSEAAAYARPKDEQSSAKSLSSNPAEDEDADEFRIDDAQLSGGQLAQHFLVDEDESEEGSDLPAASKVEVSLSSNDDDFDISLPLEQRKPVHSLHEDDESVDQSLSNQSTTDDVSELVEEPVHEMDDKTDGSAAISASAPQETQVDESQITDEQDHSMEEIVATNESIEVTYEAEETVNTSQKQDLITDLDEESEDQVHVDNRPTSTLQALKLPALQQPQIVERKAATALTTLRLQADVLEPLELTILEMDDDENEEDDDDEESSLQLMKLRLMAMNQQMIVDNAPKLSPTEAEQTQVTSSSNNLEIKQMERVPLTEFSKDVLEDITEESERLLSMSTTMEEEQDPPSLSLDESKTLLQPGAHKTGGSSSSLVSLNMLKQLEAKVQELHTQLETKDNCLASLNLQLETARRESSAGPASARDSSSLMTNSTEYRTLQEELGGPTLDIYVEMSRRDELIAKLTDSLQQSLNVRDKLQVDADRLGGEVQNLRRQLQETLDAVKRSSAVWPDQECNPGQRISEISMDLISESDDDLDRHFLTDNEERGSRSSKERQLTQLQTNEELGLQASNPEWTPTFSKQIEQFHTYLLPTEQRIFQMVQRKFDDYLNQQITLCRDLGAQELKIARDQWESEKLTSEQNQQAAHAKQMEDLRKYFEHKCADLEKQFSDDVFSHKSQHQTGDSSSECSEVDQLPEEGAAAVSSKEPSPRKRKRAELLLSPSHRQMTPCGLDSLGENTGKTEKDNTADIADLKIFYQTHIKELKRAHEDQVRKLSDRIKFYERQQGDDDYKPATESPERTCPDQESAGGVANTSLIIIDEDELNFNNESQVIQRIIEEYEKRLQEQLALARQDIATELEQQIKSLLSENTVDDQHWPKELILLREKFTAKSQLEITQLNIKHAEEMSRLKLEFEKQLNRKNKRHLTFDAARDLEQVICERDGLRELSKSFRSVLCRLAKCVAHCEEDLNATLSEEVQRLLFHSRSQDGGDDLEATISSSLNNTKHMLRVPDVHSLLEVVEDPSLVQFIDSKSNEEPSEDFDLNDCLERLKSEASYLLHLSEDLHKQRTHDESSEHLDEPEKQEHELCCEAEDGLKTTGAVNQQVLSKFLRTNSLNDQQMGVANQRKNSNPEAGKTHSSLPPDLQEHAGNASELSFQLVQLKNRLIKSEADRQNLQQQLSRTIDRNAELGQELQALRDQLSQLNSLNHTDYNEGYGLGTMKSLQEQGLDQSSASFLALQERARHLLSSSPVKEQPSRDHGNSTVILLQMIEDFCREGDKVVEFSKKDREDLQSQIDTADKQLKDTRRFLEDQAAEREQERDEFQREIERLKAQLRDKEKEHSSYANASEEYAQLESQFREVNQQLCESNAKRDKFEVELKASIDKIFVLREIISELETQVQTKALNEEVLAEKAQQLEEYVSLQMRDNDILQQEVHSLKTDIGEGYQSRIRVLEEKLKQSGPTAEQGVVLSQVAEKLRDIETTLDQKTKALESLHNSNATSNSASLSVTEDVSIHGSKEPTAVGSPSHPSLTVEGVQRVTEKLDRHTRVEEAAIKRIRDLEMQVHQMRAGCVELQHERDTLQGRMEEQTQRISTLQNRLEEQRQRAEQLHRTGTSDLNTRVHELQGEVQNLYEQLAARDKQMANMRQQLQRSKEEITRLETEVEVRTQPDRSLVNKLQAEVQQKGAEIVKLKDKIRTEMINRLAIPDLMETMLADKNDEIDHLRDQLEAKEKELQASQQEASQISSPSGAAGKQEGSGGKLSARTLSDIGSITEFPEPDVERRAAMRSLTALQMSEGAGGFLHQTMETSKEAVANLTHKRTDDLSGFIVPYPVNTFEHPHYFQALGVTAQSTDGLTPGLVPRQINFSNLTEDSKLKTTSLLMHTPELPRPTTPPEIHQLRVKLSDLQTEKQRQQSELEKKLQDLQKELEQEKEKLSRQAQTLQSYEESEAKYRLRIENLESKVLETAAQAASDRENLRKELNCVSAAHEQCENAAAARKRELEKLNSEVKVKADQLHAALRRCADLELQVLTLERDLERLKNSDNSSKQYSVDEIAQQVEKELNYSAQLDSNILKAIESEEENNLDKKLQKGVQTEEETLPGTGNGTDDENFTGERELLNQLEALRAQLAVEREQCEAMSKELLGEKQHSQDIQEQDVIIIEAMRKRLETALDAEDELHKQLDQERERCERLQTQLTSLQRAESRRNSSLLLKSPGDSPRKSPRADFESELGDRLRSEIKLLVAQNERERERSADAQRSSERERQRYEKELQERVAYCERLKQEMEKLSRDKESAETELEHFNERLTLQASEIESLEARLVTLQEAETRRANTRTRQHQENVKLQAEIHELKSKLLAAEAARDCLDQKVTQLRFDVSRSGQREAKLAEALAQANDRLAHSTDDNVPAQFMQKMKEINALLAENTQENRQMAETVQFLVGERIALQKKCEELGGAGNTNVTELEERCRQLIGRYLRVESHRKALVYQKRYLKLTLEGYQASEQLALQNLRGGAEQPPQRNIKKKFKTVALAIIAIQRIKYIGRIWHTGKRIVSKSVFTITQQRSPGLNLNVAPPQSPLPGPNSNLPTNNNNLMGRLSYAPLSPPMVNFSTVQPIMLPSDFTLQAPTTSLQTTIANNNSENTLPSLARLDWPTMQKPKRAHARHH
Protein: RNA editing complex protein MP61 (Q38EZ2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFQKALRRLQQQASQNPPVGSANIPSPYATEGGHVPIWSIVNGFVQKRNWVFRNPEWCDLCKEPVALWVNHHGRKDHALMDMHYTQMMEYPRRWNPEEVLVAFFDELQLPVETYQRSYTCYERAHRNELYSMLVELEEAKMLYFGEPRNTYLHRMQGGLRGMDHQGALVLHRYILGPFMRLYPNAHIQDFSNLVDFVTCAYNMETVYDLCGFYTLDKVALKADYKPSSPAALGLGGIAVHSSPSHGFVQNAAESQQQSRRASSTASTGSRSAADMDEEAFSRKAVFVRQLLGQLRWLTLPCEEHPAGCKFPQHLMLLGEICLKYLVVEIIAARLCEYMVRVEPVWRDHGYERVKLNVDKIMKQGRDILPEPIKYFYRPMSPNMDDLYSTKVGVLDEALEKAAVTQSLSKGV