wanglab/gogpt-training-data huggingface dataset:
Protein: Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1) (Q8I111)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTKFLSLVHLERIWSTAMSLFARQLQSLTASGIRTQQVRLASTEVSFHTKPCKLHKLDNGPNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACAVGMKAAMTEGDAVITAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGKGGSMHMYTKNFYGGNGIVGAQQPLGAGVALAMKYREQKNVCVTLYGDGAANQGQLFEATNMAKLWDLPVLFVCENNGFGMGTTAERSSASTEYYTRGDYVPGIWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRYHGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELKAIDKEVRKEVDEALKIATSDGVLPPEALYADIYHNTPAQEIRGATIDETIVQPFKTSADVLKSIGRA
Protein: Probable [Fe-S]-dependent transcriptional repressor FeoC (Fe(2+) iron transport protein C) (P64638)
Organism: Escherichia coli (strain K12)
Function: May function as a transcriptional regulator that controls feoABC expression.
Interaction partners:
- Fe
- Fe
- HTH-type transcriptional regulator MalT
- Recombination-promoting nuclease RpnA
Sequence:
MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
Protein: Mating-type P-specific polypeptide Pi (P10842)
Organism: Schizosaccharomyces pombe (Fission yeast)
Function: Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Required for meiosis, but plays no role in conjugation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MKRVAVLLKTVMCEFLKCDYNGYDRIISLLRRILTLICTPNLNGLTIKRVIDSMQSLEYIKQTCNFKLQMCISSMAFKRNNALQNCNHYAWCDDHCSDIGRPMTTVRGQCSKCTKPHLMRWLLLHYDNPYPSNSEFYDLSAATGLTRTQLRNWFSNRRR
Protein: Protein phosphatase 2C, putative (EC 3.1.3.16) (Q585N1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGVMLPKPVLSKVVDRAGNYNIGVASACVNGYRVSMEDAHVMLVESEMSLLGIFDGHNGSGCSKYIADHLPQKVKALNGKHTQEELEKVCVSLDRDFILNQSDASGSTGTFCIVTRDYNVTICNVGDSRTIIARGGRLVFVTEDHKPTAGEERQRIEACGGCVVSGRVDGDLAVSRSFGDASFKRRDALDDYKSHKVVAVPDVTTHACRQGDIIILACDGVFEGNFSNEEVAAFVNEQASKSPDLAVAAARVCDEAIRRGSKDNVSCLIARLSDGASAARLYGAHSFLPGAPYPRMHDLSRTAYVAMAQMAQVTHADALAARYALLTAHENKTLSTKSPLEQTAFEMSDETDIEAEKNFFGWGPAPGNEAAFFRSLAEQSNK
Protein: Small ribosomal subunit protein uS17c (30S ribosomal protein S17, chloroplastic) (CS17) (P16180)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA (By similarity). Required for optimal plastid performance in terms of photosynthesis and growth. Required for the translation of plastid mRNAs. Plays a critical role in biosynthesis of thylakoid membrane proteins encoded by chloroplast genes.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Small ribosomal subunit protein uS11c
- Small ribosomal subunit protein uS9c
- Small ribosomal subunit protein eS17y
- Small ribosomal subunit protein uS2m
- Large ribosomal subunit protein uL24c
- At1g64880
- Small ribosomal subunit protein eS17z
- Large ribosomal subunit protein bL9c
- Large ribosomal subunit protein uL5c
- Small ribosomal subunit protein uS10c
Sequence:
MITSSLTSSLQALKLSSPFAHGSTPLSSLSKPNSFPNHRMPALVPVIRAMKTMQGRVVCATSDKTVAVEVVRLAPHPKYKRRVRMKKKYQAHDPDNQFKVGDVVRLEKSRPISKTKSFVALPVIARAARKAEAGGDELLGLPLESQQPA
Protein: Splicing factor 1 (F1LSC3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU367126}.
Interaction partners:
- Splicing factor U2AF subunit
- Splicing factor 3A subunit 2
- Splicing factor 3A subunit 1
- Probable ATP-dependent RNA helicase DDX46
- Splicing factor 3a, subunit 3
- Cell division cycle 5-like protein
- U2 small nuclear RNA auxiliary factor 1
- Splicing factor 3B subunit 1
- Pre-mRNA-processing factor 40 homolog B
- Serine/arginine-rich splicing factor 1
Sequence:
SALGSLFWFIFPPDRLCLSLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHTLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPASNPPPPSLMSTTQSRPPWMNSGPSENRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGTPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN
Protein: TLR3 protein (Q6PCD4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MRQTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHRVLGFKEIDRQTEQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALSKKKKK
Protein: Gonadotropin subunit beta-2 (Gonadotropin subunit beta-2 precursor) (C0HA57)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU004069}.
Interaction partners:
- Glycoprotein hormones alpha chain
- Lutropin-choriogonadotropic hormone receptor
- Lutropin-choriogonadotropic hormone receptor
- Glycoprotein hormones alpha chain
- Nuclear transport factor 2
- Nuclear transport factor 2
- Fanconi anemia group A protein isoform X4
- Transcription factor SOX-14
- Thyrotropin receptor
- Thyrotropin receptor
Sequence:
MLGLHVGTLISLFLCILLEPVEGSLMQPCQPINQTVSLEKEGCPTCLVIQTPICSGHCVTKEPVFKSPFSTVYQHVCTYRDVRYETIRLPDCPPWVDPHVTYPVALSCDCSLCNMDTSDCTIESLQPDFCITHRALMDGNMW
Protein: 60S ribosomal protein L27 (K7ELC7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XRKAVIVKVSASRDSASLHAGTRLAAAGRAGLEFKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF
Protein: Serine protease inhibitor (Jellypin) (JP) (Q6J201)
Organism: Cyanea capillata (Lion's mane jellyfish) (Cyanea arctica)
Function: Inhibitor of serine proteases. Inhibits chymotrypsin, cathepsin G and human neutrophil elastase.
Interaction partners:
Sequence:
MAALQAAVSSQLAISFFSSLIVPGAEKNVVCSPLSISSALALVAAGSRGKTLKEIADALNWREDADGLAKALLAEAEKAAQNCDASCPVKTANNVWVDNEFKILDSYRDLLKSFAVNVGKADFKKHSSDETIKINSWIEDHTNKKIRDFFPPGELSEATKAVLVNALYFKGKWAEPFDMESTRDDTFHVSNSKEVQVKMMYHSAELKYFMDENSKCDLVELPYSSKAFSMMLIVPHEVEGLSAVQSSLSLSQVSGWISNVQSAAPQTVDVFLPRFKVSQKVNMKDNLKSLGINDMFSMQANLSGIAGSHDLFVSSAIHQAVIEVNEEGTEAAAATGFGVNFMSMPMQVRADKPFLFLIISNVTKSILFIGKIANPAA
Protein: WD-repeat protein GhTTG1 (Q8L5J3)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MENSTQESHLRSDNAVTYESPYPLYAMALSSTPAVTHLNYQRIALGSFIEDYTNRVHIISFDPESLTLITHPSLSFDHPYPPTKLMFQPHRKSPFSSSSDLLASSGDYLRLWEVGHSSIELISVLDNSKTSEFSAPLTSFDWNDVEPNRIGTSSIDTTCTIWDIEKGVVETQLIAHDKEVYDIAWGEGRVFGSVSADGSVRIFDLRDKEHSTIIYESPQPDTPLLRLAWNKQDLRYMATTLMDSNKVVILDIRSPTTPVAELDRHGASVNAIAWAPQSCKHICSAGDDTHALIWELPTVAGPNGIDPLSMYSASSEINQLQWSAAQPDWIAIAFSNKMQLLKV
Protein: Squamosa promoter-binding-like protein 14 (OsSPL14) (Protein IDEAL PLANT ARCHITECTURE 1) (Protein WEALTHY FARMER'S PANICLE) (Q7EXZ2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional activator that binds to the SBP-box DNA core binding motif 5'-GTAC-3'. Can target the TCP motif 5'-TGGGCC/T-3' through interaction with PCF1 and PCF2. Key regulator of the plant architecture that controls shoot branching and panicle development. Promotes panicle branching. Promotes high grain yield. Binds to the promoters of TB1 and DEP1. Suppresses rice tillering mainly through positive regulation of TB1. Regulates plant height and panicle length through positive regulation of DEP1. Repressed by D53 in strigolactone (SL) signaling. Acts with D53 to mediate the SL-regulated tiller development. Functions as a direct downstream component of D53 in regulating tiller number and SL-induced gene expression. Binds directly to the D53 promoter and plays a critical role in the negative feedback regulation of SL-induced D53 expression. Involved in defense response against pathogens. Phosphorylated at Ser-163 in response to infection by the fungal pathogen Magnaporthe oryzae. Phosphorylation reduces SPL14/IPA1 binding to the GTAC site in the DEP1 promoter and enhances binding to the TGGGCC site in the WRKY45 promoter. Binding to the promoter of the pathogen defense gene WRKY45 activates its expression, leading to enhanced disease resistance. Reduces gibberellin-mediated disease susceptibility by stabilizing SLR1. Possesses transactivation activity in yeast cells.
Subcellular location: Nucleus {ECO:0000269|PubMed:20495564, ECO:0000269|PubMed:20495565, ECO:0000269|PubMed:24170127, ECO:0000269|PubMed:28298520}.
Interaction partners:
- Os09g0512450 protein
- Os02g0621500 protein
- Os02g0593700 protein
- Os04g0476800 protein.
- Kinesin-like protein KIN-14I
- Os02g0784100 protein
- Os02g0782800 protein
- Os02g0708300 protein
- Os01g0106800 protein
- Os02g0492900 protein
Sequence:
MEMASGGGAAAAAGGGVGGSGGGGGGGDEHRQLHGLKFGKKIYFEDAAAAAGGGGTGSGSGSASAAPPSSSSKAAGGGRGGGGKNKGKGVAAAAPPPPPPPPRCQVEGCGADLSGIKNYYCRHKVCFMHSKAPRVVVAGLEQRFCQQCSRFHLLPEFDQGKRSCRRRLAGHNERRRRPQTPLASRYGRLAASVGEHRRFRSFTLDFSYPRVPSSVRNAWPAIQPGDRISGGIQWHRNVAPHGHSSAVAGYGANTYSGQGSSSSGPPVFAGPNLPPGGCLAGVGAATDSSCALSLLSTQPWDTTTHSAAASHNQAAAMSTTTSFDGNPVAPSAMAGSYMAPSPWTGSRGHEGGGRSVAHQLPHEVSLDEVHPGPSHHAHFSGELELALQGNGPAPAPRIDPGSGSTFDQTSNTMDWSL
Protein: Transcription factor BPE (Basic helix-loop-helix protein 31) (AtbHLH31) (bHLH 31) (Protein BIG PETAL) (Transcription factor EN 88) (bHLH transcription factor bHLH031) (Q0JXE7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the control of petal size, by interfering with postmitotic cell expansion to limit final petal cell size.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Auxin response factor 8
- Transmembrane protein
- Zinc finger protein JAGGED
Sequence:
MDPSGMMNEGGPFNLAEIWQFPLNGVSTAGDSSRRSFVGPNQFGDADLTTAANGDPARMSHALSQAVIEGISGAWKRREDESKSAKIVSTIGASEGENKRQKIDEVCDGKAEAESLGTETEQKKQQMEPTKDYIHVRARRGQATDSHSLAERARREKISERMKILQDLVPGCNKVIGKALVLDEIINYIQSLQRQVEFLSMKLEAVNSRMNPGIEVFPPKEVMILMIINSIFSIFFTKQYMFLSRYSRGRSLDVYAVRSFKHCNKRSDLCFCSCSPKTELKTTIFSQNMTCFCRYSRVGVAISSSKHCNEPVTLCFYSYCLRKIYHFLLWNLKYKIQKSVLFS
Protein: Eukaryotic translation initiation factor 4E-1 (eIF-4E-1) (eIF4E-1) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein) (O45551)
Organism: Caenorhabditis elegans
Function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. All 5 eIF4E proteins bind monomethyl cap structures. Only ife-1, ife-2 and ife-5 bind trimethyl cap structures which result from trans-splicing. Translation of trimethyl cap structure mRNAs may be regulated by intracellular redox state; disulfide bonds change the width and depth of the cap-binding cavity determining selectivity to mRNA caps. Required for progression through meiotic divisions during spermatogenesis and for the production of viable sperm. It is not required during oogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11641215}. Note=When associated with pgl-1.
Interaction partners:
- MIF4G domain-containing protein
- Cytoplasmic FMR1-interacting protein homolog
- Eukaryotic initiation factor 4A
- Eukaryotic translation initiation factor 5
- Guanyl-specific ribonuclease pgl-1
- RNA helicase
- SUI1 domain-containing protein
- ATP-dependent RNA helicase
- ATP-dependent RNA helicase
- Nuclear cap-binding protein subunit 2
Sequence:
MTETEQTTAPIYPLKRNWTWWYLNDERNKSWEDRLKKVYTFNTVSEFWALYDAIRPPSGLNALCDYNVFRDDIQPMWEVPENSNGGRWLIVIDKGKTPEMVDAIWLEILMALVGEQFGKDMESICGLVCNVRGKGSKISVWTKDCNDDETNMRIGVVLKEKLMAASKDHSKPLFDVIRYEDHESCQKKTSSVVKAKLSLHSSDAPVAEKSAV
Protein: Vitamin B6 salvage pathway transcriptional repressor PtsJ (HTH-type transcriptional regulatory protein PtsJ) (P40193)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Acts as transcriptional repressor of the pdxK gene, encoding a pyridoxal kinase involved in the vitamin B6 salvage pathway. Also represses transcription of its own gene. Binds to the ptsJ-pdxK intergenic region, but does not bind pdxY and pdxH promoters. Among all six B6 vitamers, only pyridoxal 5'-phosphate (PLP) clearly binds to the protein and acts as an effector molecule for PtsJ, inducing a protein conformational change that increases affinity for DNA. Thus, PLP stabilizes protein-DNA interactions, reinforcing repression.
Interaction partners:
- Pyridoxine/pyridoxal/pyridoxamine kinase
- Pyridoxine/pyridoxamine 5'-phosphate oxidase
- Pyridoxal kinase PdxY
- Putative glutamine amidotransferase-like protein YfeJ
Sequence:
MIDGKTANEIFDSIRQHIIAGTLRAEDSLPPVRELASELKVNRNTVAAAYKRLITAGLAQSLGRNGTVIKGSPSPVALEGGDPHTPLHDLSGGNPDPQRLPDLSRYFARLSRTPHLYGDAPVSPELHAWAARWLRDATPVAGEIDITSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDSEGMQPEKLERALNQGARAVILTPRAHNPTGCSLSARRAAALQNMLARYPQVVVIIDDHFALLSSSPWQPVIAQTTQHWAVIRSVSKTLGPDLRLAIVASDSATSAKLRLRLNAGSQWVSHLLQDLVYACLTDPEYQHRLTQTRLFYAARQQKLARALQQYGIAISPGDGVNAWLPLDTHSQATAFTLAKSGWLVREGEAFGVSAPSHGLRITLSTLNDSEINTLAADIHQALNR
Protein: Probable serine/threonine-protein kinase KCC4 (EC 2.7.11.1) (P25389)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in regulation of bud growth during cell cycle and in septin organization. Plays a role in cell wall synthesis.
Subcellular location: Bud neck {ECO:0000269|PubMed:11165249, ECO:0000269|PubMed:9925642}.
Interaction partners:
- Nucleosome assembly protein
- Cell division control protein 11
- Cell division control protein 3
- Cell division control protein 12
- Cell division control protein 10
- Mitosis inhibitor protein kinase SWE1
- Seventh homolog of septin 1
- Serine/threonine-protein kinase ELM1
- Probable serine/threonine-protein kinase HSL1
- Serine/threonine-protein kinase GIN4
Sequence:
MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK
Protein: High-affinity hexose transporter HXT6 (P39003)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High-affinity glucose transporter.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- High-affinity hexose transporter HXT7
- Probable glucose transporter HXT5
- Low-affinity glucose transporter HXT4
- Low-affinity glucose transporter HXT3
- High-affinity glucose transporter HXT2
- Low-affinity glucose transporter HXT1
- Carbon catabolite-derepressing protein kinase
- Hexokinase-1
- Transcription factor CSR2
- Protein ROD1
Sequence:
MSQDAAIAEQTPVEHLSAVDSASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMAHDDKPLYKRMFSTK
Protein: CAP, isoform A (A1Z867)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPNNRNRNRNRNRNKRNRNQNQNQNPSQNQNENHQQQAEGAEDREEQQDFQTQIAVAQSSSFVDDNGNSGSVSNGPTENSEEVTNTLEKTEKKEEIFEQPATVIQKEADSDAEMGAKNSKHRKEKSDKQASNGKSEEQVRPPPTIIRRPPGSPRQAKVIVHRIVREEDTANGKAQSPEPPKAVESKEQHMEVEDSKKEKPEAQQEIETKEERENEPSPKELPESSHLSEDAQQKHVEVEENQQVYDEVDYSKDETTDNNPQQEQHDSKEPEQYVLQLEKAMEFVENAHQQHVAAVQSYQKQRDTEQNAQQQEQNEAQHLQESTKAHQQNIAVPQILVDPKKREEGLAQQLHHDVKEEPILNNAQQQNDDTAPKSPKEVTIKVQFQTEDPYSQQPPPQKPTSKVIIHQIHVETTDEEQNAKPTFEEVSSTTGSLAGTLSPPPRYLVESPKNVSSGQFSNFSRNVQIQEMELNSDFSSGEFNSLQSPLVCEVDSESEGSVVLGPERSPSDQQVPSSSRVEQHEQVRQKRAQYRNALESHFMPQLLNPRYLDSILEENEWRNSTASSGGSDQTGIRTPKLNETFPRSQLDFSRRHKRREEAPSPLKLETKLLEESTDLESCTRLQSALSPQSEDAELVYLSSSASSSVSDLMELELEQAAALAERALVDLDTDASRLIARPDDEMSSTSTTTADRSETEAETETETEREGEQSRESTPVNANPTLASSQSSLLSAATPTPTPTPTPADREQLAKDTNVSGGSTVSFGAASPLAATREEFVRNMDKVRELIEMTRREQEQGELPRSPSPPPVPPPPASVPPYSPESSSFHLASLQLKRQESNDSHCSDSTTHSQCTAINLASPPPPPTAQPPTPPLRQKPAPPPVPQPVSPPAPPTPQSEPELSVADSVANANADVDADADTDTEAIKKLRLLCTEQLASMPYGEQVLEELASVAQNISDQSQNKMPYPMPQLPHIKELQLNANESKSSSAWLGLPTQSDPKLLVCLSPGQRDLVNNQTQPDDLLDAHQKFVERRGYHELSKAQVLEQDHQQQQSEMLKTAAMMRELRKSLSPPAPPVPPPPVPVKSAETAAKATAHENAKRDDASEQKQKIAACESSSLENKPRRAADLGAQQSAEQRQSSSTTTSSHKATTETMSSDTAKFPTLDSMESELARMFPQHKGDIFEEQRKRFSNIEFPSHQPVSQTKRYSNIETSSYESKKRMENGQVVYDVSTSSHEKKEQGDPPKDQPVPPVPPPPIMSATKLNGNTFIDGDVAPKNSQPSRESGSGSGNGTYEEFRQRAKAAADAFGEQREQQNGLDQDRVFKDFDRLSQQMHAELQSTREKREKSASMYDLSGFTRPASGHPRLDELQQRRHAHMQELEREIERSAKSRQERMSSVPRQMEATPPRTHEIPIELEPRSRRAESLCNLNEPPPRPHTTVGHYNHPVVQDDWSRYANDLGYSENIARPFAREVEICYQRQNQRTPHCIRAPRLSASTNDLSSSSQYSYDTFNAYGGRRTHAPMLNQAQQQQRPHYGSCYSMIERDPNPRYISTTSRRGVSPAPPPVATPQQQQVPPPAYDRQQRRSSLPRELHEQQLKYILSKEEELKFEVERLQQERRRLMEEMQRAPVLPAPQRRESYRPAAKLPTLSEDEVFRQQMAEEWMNKVAEREERRQHKIIRISKIEDEHDHSAVDKATISDEFLDRVKERRHKLSMPADSDWESGAESQPQPAAQSQPESDVEAPPVRILEGQAEANLRQLPRHLREFAKFSTSEQLPDGAQMERHEEQERREEATDNAHSSATKKTSIVKTYKVSRLPPSVQARPSYKSNGYVSEPEPNYDSDYSTVRYRTQNPHRVQSVSSAVNVRNLNQDEKLYGTMPNPIKSAQNSYKNQPGRIENYTTGHSSVSEKEKKEWWDEVMDIFNGNLEQSKLSPLYTEGNLSRALAKESGYTSDSNLVFRKKEVPVSSPLSPVEQKQAYKSLQAGGEPPLLGFRKPAPEKPRDLDPNAPPIPPQPPVKGLSSYDFPYSTDTVDGSDVNIHFKTPIRHEQRQNLSEEELAIRQAEHMQKLYHEERRRKYLQELQDMNSRRHTDNFTPSQKSPIALNRYDDFPTDVTLKSLVGPKTVARALFNFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPSKRPSEGQARAKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTSSEPLAYRALYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYVERA
Protein: Cullin 4, isoform A (Cullin 4, isoform B) (FI05474p) (LP02965p) (Q5BI50)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- DNA damage-binding protein 1
- Protein lethal
- RING-box protein 1A
- Protein cereblon
- COP9 signalosome complex subunit 5
- Cullin-associated NEDD8-dissociated protein 1
- Ubiquitin-like protein NEDD8
- Protein mahjong
- COP9 signalosome complex subunit 4
- Double parked, isoform A
Sequence:
MSAAKKYKPMDTTELHENTENIAACLKKAENVAPTAAAASSVGRSAFAAQNMNSASTNGERLPNFSKLGGSHGEIRTASTTSNLLNRMGAIHNSKPGDVKKIVIKNFKDKPTLPDNYSKDTYVKLEEAVIAIQLSKPIKYSLEELYQAVVNMCSHKMDAQLYAKLKELTEQHVKRNIKLKELTGGSMDKLILLEKINHWWLSFCQQMIMIRSIFLYMDRTYVLQNSTVHSIWDMGLDLFRIHFAQNSVVQKRTVDGLLTLIEKERQGSTVDRGLLKSLVRMLCDLQIYTSSFEEKFLDATNQLYKAESQRKMQELEVPEYLQHVNKRLAEENERLRHYLDSSTKHPLIYNVEKELLAEHLTSILQKGLDSLLEDNRLSDLTLLYGLLSRVKNGTSELCGNFNGFIKKKGRTIVIDPEKDKSMVQDLLDFKDKMDVIVRTCFEHNEKFTNSLREAFEFFINQRANKPAELIAKYVDMKLRSGNKGTTDEELEKTLDKIMVLFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDSEKSMLSKLKQECGGGFTSKLEGMFKDMELSRDINIAFRGHALSNNRDVHNLDLCVSILTMGYWPTYAPTEVTMPPQFINPQQIFNKFYLEKHSGRKLQWQPTLGNCMLRAQFDAGPKELLVSLFQALVLLLFNDKPVLSYEEILAATLIEDGELRRTLQSLACGRARVITKTPKGREILDGDQFDFNNEFTNKLFRIKINQIQMKETNEEQKATEERVFQDRQYQIDAAIVRIMKMRKTLSHNLLITELFNQLTFPVKPADLKKRIESLIDRDYMERDKDNQNQYNYVA
Protein: Chorismate mutase (CM) (EC 5.4.99.5) (AnCM) (G5EB37)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Catalyzes the Claisen rearrangement of chorismate to prephenate. Acts at the first branch point in the aromatic amino acid pathway where it steers biosynthesis towards phenylalanine and tyrosine, and away from tryptophan (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P32178}.
Interaction partners:
- Chorismate synthase
- anthranilate synthase
- Multifunctional tryptophan biosynthesis protein
- prephenate dehydratase
- Prephenate dehydrogenase [NADP
- aminodeoxychorismate synthase
- histidinol-phosphate transaminase
- Aromatic-amino-acid transaminase, hypothetical
- aromatic-amino-acid transaminase
- Imidazoleglycerol-phosphate dehydratase
Sequence:
MDTAIDLSDASKALDLANIRFQLIRLEDTITFHLIERVQFPLNKTIYIPGGVKIPNEQISLMDYLLRETERLQSRVRRYQSPDEYPFFPSALEKPILQPLDYPKILHDNDVNVNETIKTRYVQDILPAICPQFGGREDRGETQENYGSAATCDVSCLQALSRRIHFGKFVAESKFQKETEKFVALIKAGDRKEIDEAITDAKVEQKVLERLALKAKTYGTDPGFPEQSGPKIDVQAVQDMYKEYVIPLTKVVEVEYLMQRLKGTQWE
Protein: Menin (Q9WVR8)
Organism: Rattus norvegicus (Rat)
Function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair (By similarity). Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:10612420}.
Interaction partners:
- Histone-lysine N-methyltransferase
- Transcription factor JunD
- PC4 and SFRS1-interacting protein
- Retinoblastoma-binding protein 5
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Catenin beta-1
- WD repeat-containing protein 5
- Histone-lysine N-methyltransferase 2B
- Mothers against decapentaplegic homolog 3
- 5'-AMP-activated protein kinase subunit gamma-1
Sequence:
MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREAEAAEAEEPWGDEAREGRRRGPRRESKPEEPPPPKKPALDKGPGSGQSAGSGPPRKTSGTVSGTARGTEVSSAAQAPAPAASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL