wanglab/gogpt-training-data huggingface dataset:
Protein: DNA damage-inducible transcript 4 protein (HIF-1 responsive protein RTP801) (Protein regulated in development and DNA damage response 1) (REDD-1) (Q8VHZ9)
Organism: Rattus norvegicus (Rat)
Function: Regulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 complex and the GTPase RHEB. Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage. Regulates p53/TP53-mediated apoptosis in response to DNA damage via its effect on mTORC1 activity. Its role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes. Required for mTORC1-mediated defense against viral protein synthesis and virus replication (By similarity). Inhibits neuronal differentiation and neurite outgrowth mediated by NGF via its effect on mTORC1 activity. Required for normal neuron migration during embryonic brain development. Plays a role in neuronal cell death.
Subcellular location: Mitochondrion {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Interaction partners:
- Tuberin
- Thioredoxin-interacting protein
- Hamartin
- TBC1 domain family member 7
- HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
- Serine/threonine-protein kinase mTOR
Sequence:
MPSLWDRFSSSSSSSSSSRTPAADRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLLSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC
Protein: Cholinergic receptor, nicotinic, alpha 1 (Muscle), isoform CRA_a (cDNA FLJ77888, highly similar to Human muscle acetylcholine receptor alpha-subunit) (cDNA, FLJ96344, Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 1(muscle) (CHRNA1), mRNA) (Q53SH4)
Organism: Homo sapiens (Human)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKVFIDTIPNIMFFSTMKRPSREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQQG
Protein: High-affinity branched-chain amino acid transport ATP-binding protein BraF (P21629)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids.
Subcellular location: Cell inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- High-affinity branched-chain amino acid transport system permease protein BraD
- Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein
- High-affinity branched-chain amino acid transport system permease protein BraE
- Probable permease of ABC branched-chain amino acid transporter
- Branched chain amino acid ABC transporter membrane protein
- High-affinity branched-chain amino acid transport ATP-binding protein BraG
- Amino acid binding protein
- Branched chain amino acid ABC transporter ATP binding protein
- Aliphatic amidase expression-regulating protein
- Probable amino acid binding protein
Sequence:
MSRPILEVSGLTMRFGGLLAVNGVNLKVEEKQVVSMIGPNGAGKTTVFNCLTGFYQPTGGLIRLDGEEIQGLPGHKIARKGVVRTFQNVRLFKEMTAVENLLVAQHRHLNTNFLAGLFKTPAFRRSEREAMEYAAHWLEEVNLTEFANRSAGTLAYGQQRRLEIARCMMTRPRILMLDEPAAGLNPKETDDLKALIAKLRSEHNVTVLLIEHDMKLVMSISDHIVVINQGAPLADGTPEQIRDNPDVIKAYLGEA
Protein: Protein GVP36 (36 kDa Golgi vesicle protein) (P40531)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:16107716}; Peripheral membrane protein {ECO:0000269|PubMed:16107716}.
Interaction partners:
- Protein TED1
- Golgi apparatus membrane protein TVP15
- Golgi apparatus membrane protein TVP38
Sequence:
MSFNAFASSLSKKLQEISTSVSEKTQELPSLAQSTQRMVQERLGQVTDISQLPREYTELEDKVDTIKLIYNHFLGVTAIYENGSYDYPKYINESVNEFSRSVASKLTELTHATSASEAQNILVAPGPIKEPKTLNYALSKVALNSSECLNKMFPTEEQPLASALLQFSDVQAKIAQARIQQDTLIQTKFNKNLRERLSFEIGKADKCRKDVHSMRLRYDVARTNLANNKKPEKEASLRVQMETLEDQFAQVTEDATVCLQEVISHANFSEDLKELAKAQAEYFETSAGLMKEFLSNSFAEEPEAKPEVAEEEKPQTAISMNDEDDA
Protein: Torsin-1A-interacting protein 2, isoform IFRG15 (15 kDa interferon-responsive protein) (IFRG15) (Q9H496)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFSDNSHCPDCGQQWFPSLELGHWLYQTELVENECYQVFLDRINRADYCPECYPDNPANRSLVLPWSFPLEWAPQNLTRWTFEKACHPFLLGPPLVRKRIHDSRVAGFNPALQLILTRTDKTLNKKLGQNK
Protein: Arginine kinase (AK) (EC 2.7.3.3) (allergen Pen m 2) (C7E3T4)
Organism: Penaeus monodon (Giant tiger prawn)
Interaction partners:
Sequence:
MADAAVIEKLEAGFKKLEAATDCKSLLKKYLSKAVFDQLKEKKTSLGATLLDVIQSGVENLDSGVGIYAPDAEAYTLFSPLFDPIIEDYHVGFKQTDKHPNKDFGDVNTFVNVDPEGKYVISTRVRCGRSMEGYPFNPCLTEAQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKEVQQKLIDDHFLFKEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVFRRLTSAVNEIEKRIPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKMEKEM
Protein: Protein transport protein SBH2 (Ssh1 complex subunit SBH2) (Ssh1 complex subunit beta) (P52871)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Part of the Ssh1 complex, which probably is the major component of a channel-forming translocon complex that may function exclusively in the cotranslational pathway of protein endoplasmic reticulum (ER) import.
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein.
Interaction partners:
- Protein transport protein SBH1
- Protein transport protein SEC61
- Protein transport protein SSS1
- Sec sixty-one protein homolog
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4
Sequence:
MAASVPPGGQRILQKRRQAQSIKEKQAKQTPTSTRQAGYGGSSSSILKLYTDEANGFRVDSLVVLFLSVGFIFSVIALHLLTKFTHII
Protein: Trypsin epsilon (EC 3.4.21.4) (P35005)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Trypsin beta
- Trypsin alpha
- Zinc carboxypeptidase A 1
- Bazooka, isoform B
- Jonah 74E
- Peptidase S1 domain-containing protein
- trypsin
- Jonah 65Aiv
- GH01508p
- Jonah 25Bii, isoform A
Sequence:
MLKFAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTMLCAYAPHKDACQGDSGGPLVSGDRLVGVVSWGYGCGDVRYPGVYADVAHFHEWIERTAEEV
Protein: Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (P97690)
Organism: Rattus norvegicus (Rat)
Function: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9CW03}. Chromosome {ECO:0000250|UniProtKB:Q9CW03}. Chromosome, centromere {ECO:0000250|UniProtKB:Q9CW03}. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation (By similarity). The phosphorylated form at Ser-1083 is preferentially associated with unsynapsed chromosomal regions (By similarity). {ECO:0000250|UniProtKB:Q9CW03}.
Interaction partners:
- Cohesin subunit SA
- Cohesin subunit SA
- RAD21 cohesin complex component
- Structural maintenance of chromosomes protein 1A
- Nipped-B protein
- Meiotic recombination protein REC8 homolog
- Cohesin subunit SA-3
- Structural maintenance of chromosomes protein
- RAD21 cohesin complex component like 1
- Wings apart-like protein homolog
Sequence:
MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLSDEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRRVIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKREDLEKKQQLLRAATGKAILNGIDSINKVLDHFRRKGINQHVQNGYHGIVMNNFECEPAFYTCVEVTAGNRLFYHIVDSDEVSTKILMEFNKMNLPGEVTFLPLNKLDVRDTAYPETNDAIPMISKLRYNPRFDKAFKHVFGKTLICRSMEVSTQLARAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSTLSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLPSQLSLEDQKRVDALNDEIRQLQQKNRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETEGGTVLTATTSQLEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEELDRGYKSIMELMNVLELRKYEAIQLTFKQVSKNFSEVFQKLVPGAKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVPSVDQFTGVGIRVSFTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIMELAVHAQFITTTFRPELLESADKSSGKSE
Protein: Probable xyloglucan endotransglucosylase/hydrolase protein 18 (At-XTH18) (XTH-18) (EC 2.4.1.207) (Q9M0D2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
Subcellular location: Secreted, cell wall {ECO:0000305}. Secreted, extracellular space, apoplast {ECO:0000305}.
Interaction partners:
Sequence:
MKLSCGTSFAFLIMFLFAAQSMHVYAGSFHKDVQIHWGDGRGKVRDRDGKLLSLSLDKSSGSGFQSNQEFLYGKAEVQMKLVPGNSAGTVTTFYLKSPGTTWDEIDFEFLGNLSGHPYTLHTNVYTKGSGDKEQQFHLWFDPTVNFHTYCITWNPQRIIFTVDGIPIREFKNSESIGVPFPTKQPMRLYASLWEAEHWATRGGLEKTDWSKAPFTAFYRNYNVEGCVWANGKSSCPANSSWFTQQLDSNGQTRMKGVQSKYMVYNYCNDKRRFPRGVPVECS
Protein: RE32027p (Rabphilin, isoform B) (Rabphilin, isoform D) (Q6AWM2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFNRQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPDNPAH
Protein: Potassium-transporting ATPase alpha chain 2 (HK alpha 2) (Non-gastric H(+)/K(+) ATPase subunit alpha) (EC 7.2.2.19) (Non-gastric Na(+)/K(+) ATPase subunit alpha) (EC 7.2.2.13) (Proton pump) (Sodium pump) (P54708)
Organism: Rattus norvegicus (Rat)
Function: The catalytic subunit of a H(+)/K(+) ATPase and/or Na(+)/K(+) ATPase pump which transports K(+) ions in exchange for Na(+) and/or H(+) ions across the apical membrane of epithelial cells. Uses ATP as an energy source to pump K(+) ions into the cell while transporting Na(+) and/or H(+) ions to the extracellular compartment. Involved in the maintenance of electrolyte homeostasis through K(+) ion absorption in kidney and colon (By similarity). In the airway epithelium, may play a primary role in mucus acidification regulating its viscosity and clearance (By similarity).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:14749213, ECO:0000269|PubMed:7560093, ECO:0000269|PubMed:9950762}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Potassium-transporting ATPase subunit beta
- Sodium/potassium-transporting ATPase subunit beta-1
- Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
- inorganic diphosphatase
- Potassium-transporting ATPase alpha chain 1
- Gastrin
- Histamine H2 receptor
- V-type proton ATPase subunit d 2
Sequence:
MRRKTEIYSVELNGTKDVKPADQRDDKKFKGAKNKDLEPNKSHEKEELKKELDLDDHRLSNTELEQKYGTNIIQGLSSVRATELLARDGPNTLTPPKQTPEIIKFLKQMVGGFSILLWIGAALCWIAFVIQYVNNSASLDNVYLGAILVLVVILTGIFAYYQEAKSTNIMASFSKMIPQQALVIRDAEKKVISAEQLVVGDVVEIKGGDQIPADIRLVFSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDRTIIGRIASLASGVGSEKTPIAIEIEHFVHIVAGVAVSIDIIFFITAVCMKYYVLDAIIFLISIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSENQTKQAFDQSSGTWASLSKIITLCNRAEFRPGQESVPIMKRTVVGDASETALLKFSEVILGDVMGIRKRNHKVAEIPFNSTNKFQLSIHETEDPNNKRFLVVMKGAPERILEKCSTIMINGQEQPLDKSSADSFHTAYMELGGLGERVLGFCHLYLPAEQFPQSYIFDVDSVNFPTSNFCFVGLLSMIDPPRSTVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKREAKAAVVTGMELKDMTPEQLDELLTNYQEIVFARTSPQQKLIIVEGCQRQDAIVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYTLTKNIAELCPFLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKKKDRLVNTQLAIYSYLHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVAWETDDINDLEDSYGQEWTRYQRKYLEWTGSTAFFVAIMIQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIASQVIVALILSYGLGSVPALSFTMLRVQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWWDKNMYY
Protein: Cytochrome P450, family 81, subfamily D, polypeptide 8 (Cytochrome P450-like protein) (Q9SZT7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Uncharacterized protein At5g08430
- ABC transporter D family member 1
- Calcium-binding site protein
Sequence:
METKTLIFSILFVVLSLIYLIGKLKRKPNLPPSPAWSLPVIGHLRLLKPPIHRTFLSLSQSLNNAPIFSLRLGNRLVFVNSSHSIAEECFTKNDVVLANRPNFILAKHVAYDYTTMIAASYGDHWRNLRRIGSVEIFSNHRLNSFLSIRKDEIRRLVFRLSRNFSQEFVKVDMKSMLSDLTFNNILRMVAGKRYYGDGVEDDPEAKRVRQLIADVVACAGAGNAVDYLPVLRLVSDYETRVKKLAGRLDEFLQGLVDEKREAKEKGNTMIDHLLTLQESQPDYFTDRIIKGNMLALILAGTDTSAVTLEWALSNVLNHPDVLNKARDEIDRKIGLDRLMDESDISNLPYLQNIVSETLRLYPAAPMLLPHVASEDCKVAGYDMPRGTILLTNVWAIHRDPQLWDDPMSFKPERFEKEGEAQKLMPFGLGRRACPGSGLAHRLINLTLGSLIQCLEWEKIGEEVDMSEGKGVTMPKAKPLEAMCRARPSVVKIFNESV
Protein: FI21269p1 (Muskelin, isoform A) (Muskelin, isoform B) (Q0E9A5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ran-binding proteins 9/10 homolog
- WD repeat-containing protein 26 homolog
- GH10162p
- Ubiquitin-conjugating enzyme E2 H
- E3 ubiquitin-protein transferase MAEA
- Houki
Sequence:
MSSSSTSSPTDNSSHGSVALSSALNPSLNPVSGTNTSSQKPFSLSERLNFEIYRYSSYSPNYLPENVLVDCPNDQTSRWSAYTNSPPQFLTLKLRRPAIVKKIKFGKFEKSHVCNIKKFRVYGGLDDEHMVLLLEGGLKNDNVPEVFNLRCLTEDGSENLPILYLKIVPLLSWGPSFNFSIWYVELHGQDDPMYTSARMKNYNSLREVEIIKLCLKHFRQQGYLSAFGALQEQTNVQLEHPLISELHKCLVLQGDFEKAERFIVECIDEGLMDEYLHKQDYKHSWHMKHTESDIKPGNRGGHQLVVDAKRRLIYLYGGWDGYQDLSDLWVFNIEDDQWTLLCERSELSNGPTPRSCHKMVFDPISENVFMLGRYLDNSIRTSDYIKSDFYLYDTRAGNWMQICDDTSQVGGPQLVYDHQMCMDTDKRTIYVFGGKILTPRSVNATGAIEPEYSGLFSYHIATNTWAQILVDCHHASASLADVMSIKSRITHCMVFHNKHRKLYIYGGQRGKEDLDEFLSYDVDTQAISVLNKEHPHHGTIAGNEAKFEPSSGYTLRATIDCERDEIYIFSSLSKVKDRRDIQHIDASNSFWVYSLRNHKWSRIYYCRHSGQDANSINNMNILGASKGDGTLEPCPRYAHQLVYDDVTNTHYLFGGNPGICQQQQLRLDDFWLLCLEKPKREEILKHCRFLVRKLRYEEMTRQDPLKAMQYLRHHIADVIDHSDAEQLNNFHKLASLLFKNHDGNLDRECNTPALCADADDLETDSDVSAKIKEELADGPATENLSLESNESMISSGISETASSPSSSSCTKRARTDCTPELKNKRAFLFNKLVQLMPPSMVQPERNLSDFVVM
Protein: Uncharacterized protein C589.03c (Q9HE01)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Translocation protein sec63
- Uncharacterized protein C1D4.02c
Sequence:
MDLSLFSDIKDVVERDMKKNSKVVENSSARSLKNKTEENKTIDKHKSSVGPKEPKSSLEKPKANRKRKQSYGLLHDIKELGGTEEDLELIEDVESDEELEFEEPNRKQPKKDGTDAFANELNLFAKKLGFSKNSFDARALDTESEDETEIEKSSSENSDSVDVDSDDE
Protein: glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (B4DDN1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV
Protein: CCAAT/enhancer-binding protein homolog 2 (Q8IG69)
Organism: Caenorhabditis elegans
Function: Transcription factor that binds to the promoter and the enhancer regions of target genes (By similarity). Regulates expression of genes involved in fat metabolism, including ech-1.1 and fat-5. Has a protective role in response to infection by the Gram-negative bacterium P.aeruginosa. Required for the activation of infection response gene irg-1 following P.aeruginosa infection. Required to prevent P.aeruginosa ToxA-mediated lethality. May also function in concert with transcription factor zip-11 to mediate immune responses, independently of the pmk-1/p38 MAPK pathway. May act together with the bZIP transcription factor, zip-2.
Subcellular location: Nucleus {ECO:0000269|PubMed:26876169}.
Interaction partners:
- Transcription factor zip-2
- Transcription factor atf-4 homolog
- Transcription factor zip-4
- Mitogen-activated protein kinase mpk-1
- Transcription factor zip-11
- Cytochrome c oxidase subunit 5A, mitochondrial
- Histone H2A
- COX5B-domain-containing protein
- Transcription factor zip-3
Sequence:
MSGNRKRNTSEPREDDEDDYSTKRKRNNEAVNRTRQKKRQEENDTAEKVDELKKENETLERKVEQLQKELSFLKEMFMAYAKNDGNDGPPPPPPPSSSAV
Protein: Transaldolase (EC 2.2.1.2) (G8BFI3)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Interaction partners:
- Transketolase
- Triosephosphate isomerase
- Glucose-6-phosphate isomerase
- phosphoglucomutase
- Fructose-bisphosphate aldolase
- 6-phosphogluconate dehydrogenase, decarboxylating
- Fructose-1,6-bisphosphatase
- Pyruvate decarboxylase
- Pyruvate kinase
- Phosphoglycerate mutase
Sequence:
MSSNSLEQLKATGTVIVTDTGEFEQIAKYKPQDATTNPSLILAATKNPDYADVIDVAVKYAEDKGSNPKEKAEIALDRLLIEFGKRILDIVPGRVSTEVDARLSFDKEATIKKALSLIDLYKSQGIDKDRILIKIASTWEGIQAARELEKEHGVHCNLTLLFSFPQAVACAEAQVTLISPFVGRILDWYKAATGETYTAETDPGVKSVKEIYNYYKKYGYKTIVMGASFRNTGEIKALAGCDFLTIAPKLLEELYNSNDKVPKVLDAADAKNESIEKVSYINDESAFRLALNEDAMATEKLSQGIRSFGKDAATLLEQLEKKFS
Protein: Gap junction gamma-3 protein (Connexin-29) (Cx29) (Gap junction epsilon-1 protein) (Q921C1)
Organism: Mus musculus (Mouse)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}.
Interaction partners:
- Gap junction beta-1 protein
Sequence:
MLLLELPIKCRMCGRFLRQLLAQESQHSTPVGRFLLPMLMGFRLLILVSSGPGVFGNDENEFICHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGKENKEQETQISKGDHSKDVSGAKSLKLLWAYVAHLGVRLALEGAALGVQYNLYGFKMSSTFICREDPCIGSTTCFQSHPSEKTIFLNIMFGISGACFLFIFLELALLGLGRFWRIYKHKLSFLKKLPTSESSVRSKDTTDELSVVEAKEPF
Protein: Forkhead box protein G1 (FoxG1) (Brain factor 1) (BF-1) (BF1) (Forkhead-related protein FKHL1) (Q60987)
Organism: Mus musculus (Mouse)
Function: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P55316}.
Interaction partners:
- Methyl-CpG-binding protein 2
- Paired box protein Pax-6
- T-box brain protein 1
- Mothers against decapentaplegic homolog 3
- Homeobox protein EMX1
- Transducin-like enhancer protein 1
- Homeobox protein OTX2
- Sonic hedgehog protein
- Transcription factor SOX-2
- Fez family zinc finger protein 2
Sequence:
MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHPPPPAPQPPPPPPQQQQQQPPPAPQPPQARGAPAADDDKGPQPLLLPPSTALDGAKADALGAKGEPGGGPAELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH
Protein: Probable receptor-like protein kinase At2g42960 (EC 2.7.11.1) (Q9SJG2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Peroxidase 56
- non-specific serine/threonine protein kinase
Sequence:
MPPESSLNAEMSKKISFFGLKGLKLWVWVCLVVGVFIVMILCILSLWITFRRKSRRSSSKFPFNQIPHVSKDIRVDRAGFQNPHPESLYIEMNDKSTGKTMMSHLGRTKSSDNDTLSQCSSVNHHERACSSHSGEEGGFGSAGRQYGGGPVTASPLVGLPEISHLGWGHWFTLRDLELATNRFAPVNVLGEGGYGVVYRGKLVNGTEVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCIEGVHRMLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGTAQALAYLHEAIEPKVVHRDIKASNILIDDEFNAKLSDFGLAKLLDSGESHITTRVMGTFGYVAPEYANTGLLNEKSDIYSFGVLLLEAITGRDPVDYGRPANEVNLVEWLKMMVGTRRAEEVVDPRLEPRPSKSALKRALLVSLRCVDPEAEKRPRMSQVARMLESDEHPFHKERRNKRSKTAGMEIVETKDESLGPSGSETKP
Protein: Probable lipolytic enzyme (Q9HTI0)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Betainyl-CoA thioesterase
- ABC-type glycine betaine transport system substrate-binding domain-containing protein
- L-carnitine dehydrogenase
- 3-dehydrocarnitine:acetyl-CoA trimethylamine transferase
- PvdL
- NADH-quinone oxidoreductase subunit C/D
- HTH-type transcriptional regulator CdhR
- DhcR, transcriptional regulator
Sequence:
MAAKYPLSPAMWRFVEHSRAFASDSPRLDAQRAAYARMCQAFAPPRPAGLRVLDSCLPAAPPVRVRRYRPDRPAPPGGWPALLYLHGGGWMLGGLDSHDFICADLAARLGLLVLAVDYRLAPEHPFPAALQDCLRAWQALSLGELDEALDGRRLLVAGDSAGGNLAAALCLALRDGGAPSPAAQILLYPLLSAAPSPSRIDCADAPLLGLGDVQACLDAYLPLAALHRQPLALPLEAADFTGLPPAFVAVAEFDPLRDDGERYGAALRAAGGEAGFYPGSGLVHGCLRGHGIDEVEALHEALRRAVQGFLAEDSGERQAGEESTAEHQPGE
Protein: GH02096p (Maf-S, isoform A) (Q4QPP9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEAKRERKSSLAPLSPCPIPDITDDDLVSISVRDLNRTLKMRGLNREEIVRMKQRRRTLKNRGYAASCRIKRIEQKDELETKKSYEWTELEQMHEDNEQVRREVSNWKNKYKALLQFAIQNEIPIPSELEGC
Protein: Pregnancy-specific beta-1-glycoprotein 7 (PS-beta-G-7) (PSBG-7) (Pregnancy-specific glycoprotein 7) (Q13046)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MGPLSAPPCTQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSYTLHIIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLWWMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNPPAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSVTVRVSDWTLP