wanglab/gogpt-training-data huggingface dataset:
Protein: RING-type domain-containing protein (Q9N3H6)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MVNTLEGLESTRNLILKENPMRRAAELVARLSADEVTMRAAKYELIKFNRAFQNFMLVLDENIEEILMSNDNSTRIQLKKLPEFPSFSDSFMQEYEKALLNGAEKLKASTSSEKGSIPSVSFSSSISSSSAELSDARCLICLDDVISTEKTIKCNSCRRRFHLDCASQWFKEKSVCPACNRGMLDPTEFPSL
Protein: Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine hexaphosphate hydrolase) (Ap6A hydrolase) (EC 3.6.1.61) (Endopolyphosphatase) (EC 3.6.1.10) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3) (m7GpppN-mRNA hydrolase) (EC 3.6.1.62) (m7GpppX diphosphatase) (EC 3.6.1.59) (O95989)
Organism: Homo sapiens (Human)
Function: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphosphate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway (By similarity). Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with diadenosine 5',5'''-P1,P6-hexaphosphate (Ap6A) and diadenosine 5',5'''- P1,P5-pentaphosphate (Ap5A) being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Acts as a decapping enzyme that modulates the stability of a subset of mRNAs implicated in cell motility.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:34788624}. Nucleus {ECO:0000269|PubMed:34788624}.
Interaction partners:
- Bis
Sequence:
MMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVNIGRKREWFKIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPVVATTYSVSAQSSMSGIR
Protein: Uncharacterized protein (Q3UYP0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MEKGKKKEAEMEGGWLKDKTVMRGSSVQRGYSRKSPASLNSGFLHLCQAEPFQLQAGLKTPPSGLGWSDNWLPVCPAQGPKDPGASNPTPSPLSALEAHCPKELPVEEDRQGPKKPFLSLVSFLAE