wanglab/gogpt-training-data huggingface dataset:
Protein: A-factor barrier protein 1 (Q07988)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: MATalpha-specific protein that interferes with a-factor, the pheromone secreted by MATa cells. Contributes to mating efficiency. Acts to bind and sequester a-factor rather than to degrade it, and promotes the efficient mating of MATalpha cells by keeping the a-factor concentration at the plasma membrane within the narrow range needed for accurate pheromone gradient detection (Probable).
Subcellular location: Secreted, cell wall {ECO:0000305|PubMed:10383953}. Membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
- Mating factor alpha-1
- Alpha-agglutinin
- Mating factor alpha-2
- Pheromone a factor receptor
- Silenced mating-type protein ALPHA1
- Uncharacterized protein YCR041W
Sequence:
MIFAPSFSLIKNILLVSFLISHSFAAKTLTSSSNDDTLARSAAADADMAFFMEFLNDFDTAFPQYTSYMMQNHLTLPQPVADYYYHMVDLASTADLQSDIAQSFPFTQFQTFITAFPWYTSLLNKASATTIYLPQHFITGETEATMTNSSYASQKNSVSNSVPFSTANAGQSMISMANEENSTTALISASNSSSTSRTSQSQNGAHAKSLYFPMALFGIFAVAL
Protein: 60S ribosomal protein L6, putative (Q389K1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 40S ribosomal protein S13, putative
- 60S ribosomal protein L27a
- 60S ribosomal protein L13a, putative
- 60S ribosomal protein L17, putative
- 60S ribosomal protein L28, putative
- 60S ribosomal protein L35, putative
- 40S ribosomal protein S25
- 60S ribosomal protein L37a, putative
- 40S ribosomal protein S33, putative
- 60S acidic ribosomal protein P0
Sequence:
MPAATKKAVEKKAKKVSRKSPEYSTVRKSCKPGTIAIILAGRFRGRRAVILKQLPKNGPLVISGPMKYSGVPIRRIDSRYIIATSTRVDLTGVDTSAITPEIFKREKKEKRVKSEGEFMGDKDKKKAESKAKKTSKAAPKGTVSDERAQLQNAIDTALIQAIKKDPLGKEMAGYLHSVFTIKPGDAPHRLKW
Protein: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (F1LM60)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Tyrosine-protein kinase
- SH3 domain-containing kinase-binding protein 1
- Type-1 angiotensin II receptor-associated protein
Sequence:
MAEGHDAALSVAEWLRALHLEQYTALFEQHGLVWATECQGLSDASLVDMGMNLPGHRRRILAGLHRAHAPPPVPVPRPAPRPVPMKRHIFRSPPVPVTPPEPPPTAGEDQGLPAAPPIPPRRSCLPPACFTPPSTAPPDPVLPPLPAKRHSVEPSLPPVPPRTGPPYPQTSLLSKEELLLPSVSPWSQPEPTETPSTLLPAFPQGPLQPPSPPPCPPVIPPKPLRLLPEFDDSDYDDVPEEGPGAPASVMTKEEPLPSRVPRAVRVASLLSEGEELSGDDAEDEDDHAYEGIPNGGWPTIGLNPPLSSLIPDLPLHPMDELPGGSTPTTPVIKAGWLDKNPPQGSYIYQKRWVRLDADHLRYFDSNKDAYSKRFVPVACICRVAAIGDQKFEVITNSRTFAFRAESDVERNEWMQALQQAVVEHRAHIRLSSASVLGVRGGTEQPDHAGSLELRGFKNKLYVAVAGDKVQLYKNLEEFHLGIGITFIDMNVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAAQPDWASINLCIVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIQLFLQLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGVNCFSGDPAAPTPLALAEQAGQTLQMEFLRNNQSTEVPRLDSVKPSEKHYSITLPTVSHSGFLYKTASAGKPLQDRRAREEFSRRWCVLSDGVLSYYENERAVTPNGEIRASEIVCLAVSPLDTHGFEHTFEVYTEGERLYLFGLENAELAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPCKAGLSLQQAQEGWFALTGSELRAVFPEGPWEEPLQLRRLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMAWLGAIQKAAASLGDTLSEQQLGDSDIPVIVYRCIDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAGKVVEDLISHYVVVFSVDEEELRKQREEVTAIVKMRVAGTASGTQHAGDFICTVYLEEKKVETEQHVKIPASMTAEELTLEILDRRNVSIREKDYWTCFEVNEKEEAERPLHFAEKVLPIVHGLGMDSHLVVKKYPSMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSHRPEKEWPVKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELREWFATFLSVQHDGLVWPSEPSRVSRAVPEVRMGSVSLIPLRGSENEMRRSVAAFTADPLSLLRHV
Protein: Contactin associated protein-like 2 (D8WUA6)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Cell junction, paranodal septate junction {ECO:0000256|ARBA:ARBA00004403}. Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MVVVTRAGCRAALFLWIFISISCRARTALPASQKCDEPLVSALPHSSFSSSSSMTSSYVPGYAKLNKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNTNSDSVVRHDLQHPVIARYVRIVPLDWNGEGQIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVISLKFKTSESEGVIFHGEGQQGDYITLELKKAKLVLNLNLGSNQLGSIFGHTSVTTGSLLDDHHWHSIIIERHGRNINLTLDRHMQHFRTNGEFDYLDLDYEITFGGMPFSGKPSSNSRKNFKGCMESINYNGNNITDLAKRKKLEPSNVGNLSFSCVEPHTVPVFFNATSYLEVPGRQSQDLFSVSFLFRTWNPNGLLLFSHFADDLGNVEIDINEGKVSVHINVSQVKKNRIDISSGSGLNDGQWHEVRFLAKENFAVLTIDGDEASAVRTNSPLQVKTGEKYFFGGFPVQMNDSDHSLFEHSFQGCMQSIHVDDQLVDLHAVEQGELGSFANVTIDMCAIIDRCVPNHCEHDGKCTQTWDSFKCTCDGTNYSGATCHNSIYELSCEAYKHLGRTSNYYWIDPDGSGTLGPLKVYCNMTEDKVWTTVYHDLQMQTSVGGNSPEKLSVLQLNYSATMDQISAITSSAEYCEQFISYSCKMSRLLNTPEGNPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDSGMLSYKEHLPVSQVVVGDLDRPGSEAKVSVGPVRCQGDRNYWNAASFVTSSSYLHFSTFQGETSADISFYFKTSASDGVFLENLGNTDFIKLELKSATEVSFSFDVGNGPVEIVVRSPNPLNDDQWHRVNAERNVKQASLQVDQLPLEVRKAPTEGHTRLELYSQLYVGAAGGQRGFLGCIRSLRMNGVTLDLEERAKVTPGVKPGCSGHCTSYGMYCANGGKCVEKYNGYSCDCSKTAYDGPFCIKDVGAFFEEGMWLRYNFHSPGTSMKDLVSRTLLSSADPEITAPDLSLNKEELSFSXSTTKSPCVLFYVSSYTPDFMAVLVNPTGNLQIRYNLGGTKEPYNIDIDHRNMANGQPHTVNVTRNGRDIVLQLDHYPPTSYSLPATSDIQFNSPKALFLGKVIEIGKIDQDIYKYNTPGFTGCLSRVQFNQIAPLKAALRPTNASSHVHIQGELVESNCGASPLTIPPMSAATDPWHLDSASADFPYNGQAIGDGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI
Protein: Uncharacterized protein (Q57VM6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- T. brucei spp.-specific protein
- BRCT domain-containing protein
- Inositol hexakisphosphate
- Uncharacterized protein
- Recombination initiation protein NBS1, putative
Sequence:
MSPSSLTLRYVLPCHSCTSCDEATVADRVSLLDTPSVPVITWTTPSEFLTAVKATVPVDSAKHNGSLAVGEDGLGLHLLSADSAGAAAGDGEAGPRVIQLTLDWVLALPCVSDDAEGNSGVELHVLRTNRLDFLVQTWSAVTSHIVRLTTWPRMEVSFFPSGFPCEIVSGMINGSEPSYYEVRACIPIRLVLSPTPEGTKERKNDDRGSVSEMLEEFASTKRMYAHQLRALIHDAAFSCISSNPTSFCGFDEAPSSGRGTDTASPGESVKEEEAVSSASTNQQSGGGVSAGKEPKGPQQVLPRVFHSIPPPPVPVALNICLTHHGEDGEVPTEGDDQRERDVVLFVHTVVRAVRPRSGASPRLRPRRIALDALVNLFPERFAVHGVSDVAVAEVNVEDLSCMWVPFNDTTIGGDVLALSAEEYFSFHGRQDSEASGQASPRGNGSKMQHNPYDRMRVSPADVDPHGRKTAPQPCFGWGRGMCFNGGGPGRPFTFNPALCGTFQCFPWTPSFALRKGRTASAGAAETSEVRDVVRSSWTGVSSWKNVTPGLSCSWRGESSGSRRGGKSGSLRSGASEAPWAPWAAETPDDVSVKVPPQAEETSAVSASPQDDNEVMDLSDSRQMILEWADSIGLSRRRTANLAQQLERLGEQFASISLQHCVTTDGADKRKKGRGGRNGQKAVDAGAPEEDSDAVHLVEGLIGASMRPHGSISEEVLRFAARLLGGAKQCEEDYGSVDECAKEAFDMIQKLDQDLRATALEVQRTQKDIRKTLSGILTPKGERKAKVETPNLFYPAIKALNPEQSHRTELFGIGAPSGLSRSGDILTLLRFKKGDYEVAEQSVMTVSDKLRKAEVWCAAQLEQMQLVVKLYKDILVPCLDARVATKRDEERKRSKLIVDWAVSIAIVLESQRSAESQESNGVERHEDEHLSHKGPRGAASTEKPLRLSNGKPLLNGGSNGRAHEGQAEPLKTHDATTRSEGKGLEASSERPAKVERPVKAERPAKTERPMKADRVAPPVTETTRDLHRSTSPKRKRKAPAVVAQPWSLMTVTPAPVVTTQRRGSRYRRFLWRLARFSQVDRLRRNAYLLALLASVAVAYLVVVFLYG
Protein: RE68725p (Syntrophin-like 2, isoform A) (Syntrophin-like 2, isoform B) (Q8SX22)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MKLSDTMATPIEEKLDQNLKVRTGMVHVSDGKSRPEPLRLNLTMELLSLQKLEVVTPSSCHPNGPPMESKERMVQITRQKQGGLGLSIKGGAEHKLPILISRIYKDQAADITGQLFVGDAIIKVNGEYITACPHDDAVNILRNAGDIVVLTVKHYRAATPFLQKQLTKDTPDSDNDVTCAELKADEGYKSSVNSGTISRSCSRPMSICSEPEKRWTDVVAVPLMMAYVTRYIYGTDKLRQNAFEVRGLNGISTGVIHCDELAILSQWLKLITDNVVGLTHLQMKLYNRNFAVGERIEYMGWVNEGVINNNISWQSYKPRFLLLKGTEVMLFETPPLNVAGISKALVVYKVYQTMFRIVKESETVDSRQHCFLLQSSGHEPRYLSVETRQELLRIENSWNAAIVTSVIKLGRKTFAVSHHGKSGGLTLDWQAGFSLTEGAESATVWQYKFSQLRGSSDDGKSKLKLHFQDHDSRAIETKELECQVLQSLLFCMHAFLTAKVASVDPAFLSSIQQT
Protein: Not1, isoform H (EC 3.1.13.4) (A0A0B4LEZ3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- CCR4-NOT transcription complex subunit 4
- CCR4-NOT transcription complex subunit 3
- CCR4-NOT transcription complex subunit 10
- CCR4-NOT transcription complex subunit 9
- Regulator of gene activity
- CCR4-NOT transcription complex subunit 11
- poly
- poly
- ATP-dependent RNA helicase me31b
- Protein associated with topo II related - 1, isoform A
Sequence:
MCPRLRAVAVKALILASKPYAMQLFDSKPYITDSIYDILQFVKEHGLEADRSSLRHLFSVINFSDLVPSVTVQLQAKLLGIQLERQLHSSSFVSNICYAFDQFFASNQKQSLKPVAVADLVGQVARLTGINKVCECVFALALTHSSYTELKHSARNNLKGSLSELIDSYLGNKGTGPADSGLREISFDLLQYLLCCLSEYVQPQVEAQFLIKLREEFPRQAVPLVLAPFLYGSTTATIAGAGASETDAEAEATTNSNSSSFEADALNEVGIEDIYDHLSEIIFTNQGKNNIMDTSWINLILEIGYEFTSSVEECKNHLCSRERERAELQSKDVAKIVGLMCRRHSSLLDCNVNLPTPANFWPGQGQGGGSNSSGSSQTQITPQQQNPGSSNNNDGSDGNSSSDKKDKKETTEATQTWKPDVFVQALKEVVPQLNWKDVCMELDHPEFVLKDRIGLELLLTILRLATGSNIFPHPECIYRHWANTEGQLSLIATMLKNPDLFSFADFVFSQPALDVLKTAPDADNKEISSWKSLHLVEVLLSIADKGYYTQVHELFKFPAQNCPDVLFLALLNTSPPMTPLRQDLFNQLIPTFLGNHPNSNVILASAWSSNNFQLRSNIMNAMSEWYLRGNEFDQVKLSRILDLAQDLKALSALLNARSFLFIIDLACLASRREYLKLEKWLTDKIREHGEPFMQAIIKVLHRRCPQVINAKVPEDQLPPKQAQLLPETVTTMINCLQTCINNCMQPEMVEVIMQMTANVAIMANKARAQQQQQPGLVPPPPPTILRGHRGMDLPGGIVPPPPQQPFSGNLNAQMFGPGMDPLTNMSNNLAGLNLSGPNGAFNFGNMLTSPSRLMTPGANPYPLNLMQMPQAPPPPNVGNLGRMLPGGPQQQTPTPTPTAPNPNNPVMADLQIPVSKEVEDEVNSYFQRIYNHQPNPTLSIDEVLDILQRFKESSNRREQEVFLCMLRNLFEEYRFFCQYPEKELQITAQLFGGIIDRNLVPTFVALGLSLRCVLDALRKPDGSKLYYFGVTALDRFRTRLHTYNKYCEHIRSIPHFSDFPPHLIQYVEYGMHGQEPPPQKLIGLSNTIPSAISSGPGTEPIYRNSSMLGNMPAATPGSGPKSNAAVSHATRMKSIANATNIDTLLVANQEEKVTVPPEPVQDKTAFIFNNLSQLNIPQKCDEIKEIMTKEYWPWLAQYLVLKRASMEFNFHTLYYNFLDALKNGEINRFVTKETLRNIKVLLRSDKGVINFSDRSLLKNLGHWLGMMTLGRNRPILQLDLDLKSLLAEAYHKGQQELLFVVPFVAKILESSAKSRIFRSPNPWTMGIMYVLAELHQEPDLKLNLKFEIEVLCKTLNLELAKLRQVIYLKDPNRTHRIEEQMSQPKPKQLEPVASAPALPREQQSPAQPPPPPQQQQPPQQQVPPPPSSADVDAQNAAAMMMAAGGANSTPGSVSSPNLPTDSSQVALPPPEPRYSYVDVNVSNFQLIGQQLVLPPNTPFLHANPGIKHMVVNAVERTITDWLQPIVDRSIRIACATTEQIIRKDFALDADENRMRTAAHQMVRNLAAGMAMITGKDEIARAISQNLHKALLSGLNGMPSMAEIQAAAMQLASENVELVCAFIQKTSAEKAAAEIDRRLSTDFETRKIAREEGNRFVDAQILTYQQERLPEAVRIKVGAAPATLYAVYSEFARSIPGFQQMSDRDIALFVPKPTDLSQPNVFANDDSMVYGELASKMEAFMNTAIGVPTLQIQASKMHMLLNALIATRRLRDQESAFNLLTRAVEGLTEGLVNMHENMEQMKMYQNIHLRILGLLNNSFGAPNTERAVTKCFFDIREEVRYNVEAARALITSHFVNLNQFDGMLRDCMDNGNNYVAISFGIALLERLIMDDRVINIVSDNEFMATVELLGRLTQHRHRYPECIVNAIDTLWSGNFNSSSDYSPFNGNDRYLSGASHYIHSGMHHVRSCDTDDPPGLQEKTEFLLKDWVALYTQQNQQSTRDARNFGAFVQKMNTYGILKTDDLITRFFRQATHICTDVVYRMFAEPSLPINQAKNKIFQWIDAFVHLIAMLVRHSGEAGNPTTKINLLNKVLGIVLGTLIKDHEMRGVSFQQVGYHRFFMMLFMELCTADVILESLMHSIVSAFAYTYHLLNPSVAPGFCFAWLELISHRVFLGRILVQIPGQKGWPLYAQLLQDLFKYLAPFLRNTELGKPVQLLYKGTLRVLLVLLHDFPEFLCDYHFGFCDTIPPNCVQMRNIILSAFPRNMRLPDPFTPNLKVDMLSDSSNAPKVLSSYIMNIQPANFKKDLDSYLKARAPVTFLSELRGHLQVTSEPGTRYNMALMNALVMYVGTQAIALIRNKNFVPNTSNIAHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCAVLHLFAEANSEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPIYKFWDHDFVHCAPEITKLFESVARSCLAKSNVTQQLNMPVVDGEGQEVATIN
Protein: Cold-inducible RNA-binding protein (Glycine-rich RNA-binding protein CIRP) (K7EMY9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSSGGS
Protein: Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297) (O15040)
Organism: Homo sapiens (Human)
Function: Probably plays a role as positive regulator of autophagy.
Interaction partners:
- Gamma-aminobutyric acid receptor-associated protein-like 2
- GABA type A receptor associated protein like 1
- Microtubule-associated protein 1 light chain 3 gamma
- Vacuolar protein sorting-associated protein 41 homolog
- Spatacsin
- Vacuolar protein sorting-associated protein 16 homolog
- AP-5 complex subunit zeta-1
- Microtubule-associated protein 1 light chain 3 beta
Sequence:
MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGLRLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGWVLSWNEYSIYLLDTVNQATVAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTSTVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDEPCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSAEQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGSVGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQQDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGAGLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALSDDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYREGVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDDDHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSLLGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLWLCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEPPVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTGITEEMPVGTAWEHVPGLQACQLALSTRTVWARCPNGDLARRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYLLQRLTKTFSHSHGTQKSSQAAMPHPEDLEDEWEVI
Protein: Adhesion G-protein coupled receptor G2 (G-protein coupled receptor 64) (Rat epididymis-specific protein 6) (Re6) (Q8CJ11)
Organism: Rattus norvegicus (Rat)
Function: Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within epididymis.
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:12420295}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Lymphocyte antigen 6 complex locus protein G5c
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-4
Sequence:
MLFSGGQYSPVGRPEEVLLIYKIFLVIICFHAILVTSLKENAGNSSLLSPSAESSLVSLVPYSNGTPDAASEVLSTLNRTEKSKITILKTFNASGVKSQRNICNLSSICSDSVFFRGEIVFQHDDHYNVTQNQDIVNSTFAGVLSLSELKRTELNKTLQTLSETYFIVCATAEAQNTLNCTFTVKLNETMNVCAMMVTFKSVQIRPMEQCCCSPRTPCPSSPEELEKLQCDLQDPIVCLADQPHGPPVSSSSKPVPVVPQATIFSHVASDFSLAEPLDHALMTSSTPSLAQETRLPSPQPTISLTSSPAIDLPVQHVVASSSLPQTDLSHTLSPVQSSIPSPTTAAPSVPEKVVAISTPPGETVVNTSSVPDLEAQVSQMEKALSLGSLEPNLAGEMVNRVSKLLHSPLALLAPLAQRLLKVVDAIGLQLNFSSTTISLTSPSLALAVIRVNASNFNTTTFAAQDPANLQVSLEAQAPKNSIGAITLPSSLMSNLPASEVELASRVQFNFFETPALFQDPSLENLSLISYVISSSVTNMTIKNLTRNVTVALKHINPSQDDLTVKCVFWDLNRNGGRGGWSSDGCSVKEKRMNETICTCSHLTSFGILLDLSRTSLPPSQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYNARGFCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGIPAVVVSIVLTISPDNYGIGSYGKFPNGTPDDFCWINSSVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNLTFMYLFAIFNTLQGFFIFIFYCAAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSNSLQSSCNSTNSTTLLVNSDCSVHASGNGNASTERNGVSFSVQNGDVCLHDLTGKQHMFSDKEDSCNGKSRMALRRTSKRGSLHFIEQM
Protein: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (A0A2U3TZT9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Lipid droplet {ECO:0000256|ARBA:ARBA00004502}.
Interaction partners:
Sequence:
MAAEEEEVDSADTGERSGWLTGWLPTWCPTSISHLKEAEEKMLKCVPCTYKKEPVRISNGNKIWTLKFSHNISNKTPLVLLHGFGGGLGLWALNFGDLCTNRPVYAFDLLGFGRSSRPRFDSDAEEVENQFVESIEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILVEPWGFPERPDLADQDRPIPVWIRALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDDTVTEYIYHCNVQTPRLFLGQDIMYMQINQKNSTRK
Protein: E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (RING-type E3 ubiquitin transferase listerin) (Zinc finger protein 294) (O94822)
Organism: Homo sapiens (Human)
Function: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:28757607}.
Interaction partners:
- Ribosome quality control complex subunit NEMF
- Ribosome quality control complex subunit TCF25
- Large ribosomal subunit protein uL5
- Transitional endoplasmic reticulum ATPase
- tRNA endonuclease ANKZF1
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein eL6
- E3 ubiquitin-protein ligase ZNF598
- Large ribosomal subunit protein eL31
Sequence:
MGGKNKQRTKGNLRPSNSGRAAELLAKEQGTVPGFIGFGTSQSDLGYVPAIQGAEEIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTMCTERDTETVKGVLPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKQLAPYLKSLMGYWLMAQCDTYTPAAFAAKDAFEAAFPPSKQPEAIAFCKDEITSVLQDHLIKETPDTLSDPQTVPEEEREAKFYRVVTCSLLALKRLLCLLPDNELDSLEEKFKSLLSQNKFWKYGKHSVPQIRSAYFELVSALCQRIPQLMKEEASKVSPSVLLSIDDSDPIVCPALWEAVLYTLTTIEDCWLHVNAKKSVFPKLSTVIREGGRGLATVIYPYLLPFISKLPQSITNPKLDFFKNFLTSLVAGLSTERTKTSSLESSAVISAFFECLRFIMQQNLGEEEIEQMLVNDQLIPFIDAVLKDPGLQHGQLFNHLAETLSSWEAKADTEKDEKTAHNLENVLIHFWERLSEICVAKISEPEADVESVLGVSNLLQVLQKPKSSLKSSKKKNGKVRFADEILESNKENEKCVSSEGEKIEGWELTTEPSLTHNSSGLLSPLRKKPLEDLVCKLADISINYVNERKSEQHLRFLSTLLDSFSSSRVFKMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKLIGWLNEDQRKDFGFLVDILYSALRCCDNDMERKKVLDDLTKVDLKWNSLLKIIEKACPSSDKHALVTPWLKGDILGEKLVNLADCLCNEDLESRVSSESHFSERWTLLSLVLSQHVKNDYLIGDVYVERIIVRLHETLFKTKKLSEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICKLKNTWLSGVNLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNTLLESEDSYLMGVYIGSVMPNDSEWEKMRQSLPMQWLHRPLLEGRLSLNYECFKTDFKEQDIKTLPSHLCTSALLSKMVLIALRKETVLENNELEKIIAELLYSLQWCEELDNPPIFLIGFCEILQKMNITYDNLRVLGNTSGLLQLLFNRSREHGTLWSLIIAKLILSRSISSDEVKPHYKRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQCIPALLGWTKKDLCSTNGGFGHLAIFNSCLQTKSIDDGELLHGILKIIISWKKEHEDIFLFSCNLSEASPEVLGVNIEIIRFLSLFLKYCSSPLAESEWDFIMCSMLAWLETTSENQALYSIPLVQLFACVSCDLACDLSAFFDSTTLDTIGNLPVNLISEWKEFFSQGIHSLLLPILVTVTGENKDVSETSFQNAMLKPMCETLTYISKEQLLSHKLPARLVADQKTNLPEYLQTLLNTLAPLLLFRARPVQIAVYHMLYKLMPELPQYDQDNLKSYGDEEEEPALSPPAALMSLLSIQEDLLENVLGCIPVGQIVTIKPLSEDFCYVLGYLLTWKLILTFFKAASSQLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYAETAVEVPNKDPKTFFTEELQLSIRETTMLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRVFNIVDRFTSKYVSSVLSFQEISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELIIQLPSNYPLGSIIVESGKRVGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFEGVEDCMICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF
Protein: Outer kinetochore KNL1 complex subunit ZWINT (ZW10 interactor) (ZW10-interacting protein 1) (Zwint-1) (O95229)
Organism: Homo sapiens (Human)
Function: Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
Subcellular location: Nucleus {ECO:0000269|PubMed:38459128}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:15485811, ECO:0000269|PubMed:15502821, ECO:0000269|PubMed:16732327, ECO:0000269|PubMed:27881301, ECO:0000269|PubMed:38459128}. Note=Localizes to kinetochores from late prophase to anaphase (PubMed:15502821, PubMed:27881301). Localizes to kinetochores both during mitosis and meiosis (By similarity). {ECO:0000250|UniProtKB:Q9CQU5, ECO:0000269|PubMed:15502821, ECO:0000269|PubMed:27881301}.
Interaction partners:
- Outer kinetochore KNL1 complex subunit KNL1
- Kinetochore-associated protein DSN1 homolog
- Centromere/kinetochore protein zw10 homolog
- Kinetochore-associated protein NSL1 homolog
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Polyamine-modulated factor 1
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Kinetochore protein NDC80 homolog
- Kinetochore protein Nuf2
- Protein MIS12 homolog
Sequence:
MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDRVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
Protein: MvaT (Q9HW86)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Integration host factor subunit alpha
- DUF721 domain-containing protein
- Uncharacterized protein
- Flippase-like domain-containing protein
- cAMP-activated global transcriptional regulator Vfr
- DUF2334 domain-containing protein
- Response regulator GacA
- Regulatory protein RsaL
- Uncharacterized protein
Sequence:
MSLINEYRATEEAIKELQERLKSLEQDDKLKKELEFEEKLRTLMGTYQKSLRDVISLLDPDAKIGKSTRTAKAPAGKRARKVKQYKNPHTGEVIETKGGNHKTLKEWKAKWGPEAVESWATLLG
Protein: Unconventional myosin-VI (Unconventional myosin-6) (A0A0A0MRM8)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, microvillus {ECO:0000256|ARBA:ARBA00004105}. Cell projection, ruffle membrane {ECO:0000256|ARBA:ARBA00004632}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane, clathrin-coated pit {ECO:0000256|ARBA:ARBA00004600}.
Interaction partners:
Sequence:
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYAQQNPAAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQNAIESRQARPTYATAMLQSLLK
Protein: T-cell leukemia homeobox protein 2 (Enteric neuron homeobox protein) (Homeobox TLX-2) (Homeobox protein Hox-11L1) (Hox11L.1) (PMUR10F) (Q61663)
Organism: Mus musculus (Mouse)
Function: Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MEPAVLAAHHLPHHEPISFGIDQILSGPEPPGGGLGPGQSGQSHGESAAFSSGFHGASGYAPAGSLASLPRGSGVGPGGVIRVPAHRPLPVPPPSGAAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
Protein: NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3) (Q8TBC4)
Organism: Homo sapiens (Human)
Function: Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
Interaction partners:
- NEDD8-activating enzyme E1 regulatory subunit
- NEDD8-conjugating enzyme Ubc12
- Ubiquitin-like protein NEDD8
- NEDD8-conjugating enzyme UBE2F
- Cullin-1
- E3 ubiquitin-protein ligase RBX1
- Ubiquitin-like modifier-activating enzyme 5
- DCN1-like protein 1
- Sentrin-specific protease 8
- Cullin-5
Sequence:
MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS