Protein: Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3) (Q9W7R4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion (By similarity). Required by retinal ganglion cells for acquisition of their correct morphological and functional connectivity, thereby playing a key role in the development of the visual pathway.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9WTS6}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9WTS6}. Cell projection, axon {ECO:0000250|UniProtKB:Q9WTS6}.
Interaction partners:
- Teneurin transmembrane protein 2.
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L2 isoform X9
- Si:dkeyp-98a7.4.
- Si:dkeyp-98a7.8.
- Zgc:171717.
- Zgc:113984.
- Adhesion G protein-coupled receptor L3
- DEAD
- Si:dkey-90l23.1.
Sequence:
MDVKERRPYCSLTKSRREKERRYTGSSGDSEDCRVPTQKSYSSSETLKAFDHDSSRLLYGGHVKEMVHREADEYSRQGQNFNLRQLGICEPATRRGLAFCAEMGMPSSLSSPSVTEHSHSQPPSPNLHDNQSSILSNATTQAVQDSDSEEEYTAVLYRPVTQPAPSHSCNEQPSNQHQQGQSTLPPVPPPHKQQPSVTALNHNSLSSRRNVSPAPPAALPAELQTTPESVPLQDSWVLGSNVPLESRHFLFKTGTGTTPLFSTATPGYTMATGAVYSPPTRPLPRNTLSRSAFKFKKSSKYCSWRCTALSAMAVSILLSVLLCYCIAMHLFGLNWQLQETEGYAFENGQVKSDSTATNAVTALSTENKVYFQENNTIDTGEVDVGRRAVQDVPPGTFWRTQLFIDQPQSLKFNISVQRGALVGVYGRKGLPPTHTQYDFVELLDGSRLIAKEKRGLVEVEGAARKARSVNVHEAEFIRFLDSGTWHLAFYNDGKNAEQVSYNTIIIDTLTECPHNCHGNGDCRTGTCHCFPGFLGPDCSRAACPVLCSGNGQYSRGRCLCYSGWKGTECDVPSNQCIDIHCSGHGICIMGTCACNTGYKGDNCEEVDCLDPSCSSHGVCIHGECHCNPGWGGNNCEILKTMCPDQCSGHGTYQTESGTCTCDTNWTGPDCSIEVCAVDCGSHGVCIGGSCRCEEGWTGSVCDLKACHPRCTEHGTCKDGKCECHQGWTGEHCTVEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAMETLCADGKDNEGDGLVDCMDPDCCLQSSCQTQPFCRGSPDPIDIISQNQPASPQQAAQSFYQQISFLTGPESTHVINGENPFNRSLVSIIRGQVLTADGTPLIGVNVSFVHYPDHGYTITRQDGMFDILANGGASLTLSFERAPFLTQFRTVWIPWNVFYVMDTLVMKKEENDIPSCDLSGFIRPSPLIVATPLSTFFRSSPENGPIIPETQVLQEETAIPGSDLNLMYLSSRAAGYRPVLKVTMTQATIPFNLMKVHLMVAVVGRLFQKWFPAEPNLSYTFIWDKTDAYNQRVYGLSEAVVSVGFEYESCLDLILWEKRTAILQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENVFVSQQPPVISTIMGNGRRRSISCPSCNGQADGNKLLAPVALACGSDGSLFVGDFNYIRRIFPSGNVTSVMELSNNPAHRYYLATDPMTGQLYVSDTNSRRIFRPKALTGTKELLQNAEVVAGTGEQCLPFDEARCGDGGKATEALLLGPKGIAVDKNGFIYFVDGTMIRKVDRNGIISTLLGSNDLTSARPLTCDNSMHIGQVRLEWPTDLAINPMDNSIYVLDNNVVLQITENRQVRIVAGRPMHCQVPGIEYTMGKRAIQTTLEGATAISLSYSGVLYIAETDEKKINRIRQVSTDGEISHLAGAPSDCDCKNDANCDCYQTGDGYAKDARLNAPSSLVVSPDGTLYVADLGNIRIRAIRHNRPPQGSSGLFEVASPASQELYVFDSNGTHQYTMSLVTGDYKYNFSYSNEDDVTAVTDSSGNTLRVRRDPNRMPVRIVAPDNQVIWLTIGTNGGLKTLTAQGQELVLFTYHGNSGLLATKSIQIGWTTFYDYDSEGRLTNVTFPTGVITSLIGEMDRALTVDIETSGRDDDVSITTNLSSIDSFYTLVQDQLRNSYQVGYDNSMRVIYANGMDSHFQTEPHILAGASNPTVARRNMTLPGENGQNLVEWRFRKEQNRGKVVVFGRKLRVNGRNLLSVDYDRSLRTEKIYDDHRKFLLKIVYDASGHPTLWVPSSKLMSVNLTYSSTGQVTSLQRGPTTERVEYDSQGRIVSRTFADAKIWSYTYLDKSMVLLLHSQRQYIFDYDLQDRLSAITMPSVARHTMQTIRSVGYYRNIYNPPESNASVTVDYSEDGQLLRVAHLGTGRRVLYKYRRQNKLSEILYDSTRVSFTYDETAGVLKTVNLQSEGFICSIRYRQIGPLVDRQIFRFSEDGMVNARFDYTYDNSFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQIISTAVMTYTKHFDVHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYGYEYDVDGQLQTVYLNEKMMWRYNYDLNGNLHLLNPGNSARLTPLRYDLRDRITRLGDVQYRMDEDGFLRQRGAEIFEYNSKGLLVRVHSKASGWTIQYRYDGLGRRLASRNSLGQHLQFFYADLNYPTRITHVYNHSSSEITSLYYDLQGHLFAMEISSGEEFYIACDNTGTPLAVFSSNGLLLKQVQYTAYGEIYFDSNPDFQLVIGFHGGLYDPLTRLLHFGERDYDIQAGRWTTPDISTWTRVGKDPAPFNLYMFRNNNPISKIHEVKEYVTDVNIWLVTFGFHLHNVIPGFPIPKFDLTQPSLEMRKSQLWDDLPSISGVQQEVMRQAKAFLSFERMPEIQLSRRRSSREKPWLWFATVKSLIGKGVMLAITSKGQVATNALNIANEDCIKVATVLNNAFYLEDLHFTVEGRDTHYFIKTSLPESDLGALRLTSGRKSLENGVNVTVSQSTTVVNGRTRRFADVELQYGALALHVRYGMTLDEEKARVLEQARQRALSSAWAREQQRVRDGEEGVRLWTEGEKRQLLSSGKVLGYDGYYVLSVEQYPELADSANNVQFLRQSEIGKR