wanglab/gogpt-training-data huggingface dataset:
Protein: Twinfilin-1 (Twinfilin-A) (P53250)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. Prevents actin filament assembly by forming a 1:1 complex with actin monomers, and inhibits the nucleotide exchange reaction of actin monomers (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Actin
- F-actin-capping protein subunit beta
- Cofilin
- Adenylyl cyclase-associated protein
- Profilin
- Actin-interacting protein 1
- Fimbrin
- Actin-binding protein
- Coronin-like protein
- Protein AIM7
Sequence:
MSTQSGIVAEQALLHSLNENLSADGIVIIIAKISPDSTSVHQTQVARSFEELVQLASQEREPLYIFYKPEGLDKYFFVSFIPDGSPVRSRMLYASTKNTLARQVGSNSLSTEQPLITDAQDLVDLKNFDSARPAGQNKPLTHDEEMQIEINKQQALLRKNTSVKLVSQDSASPLSLTFRVNSEKPINEILDSEGKNLIIFQIDPSNETIQIVQSDTCPSVDELYIDLPGPSYTIFRQGDSSFFIYSCPSGSKVKDRMIYASNKNGFINYLKNDQKIAFSKVVEIGDFVELDKSLLMATNKEDSLDHGSNPDLPNKSNLKFNKPKGPLRKRRT
Protein: Arsenate reductase 2.2 (OsACR2.2) (EC 1.20.4.1) (Dual specificity phosphatase CDC25.2) (Sulfurtransferase 21) (OsStr21) (Q10SX6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Possesses arsenate reductase activity in vitro. Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. May play a role in arsenic retention in roots.
Interaction partners:
- Os11g0586100 protein
- Wee1-like protein kinase
- Cyclin-dependent kinase A-1
- Cyclin-dependent kinase A-2
- [RNA-polymerase]-subunit kinase
- protein-serine/threonine phosphatase
- Cyclin-dependent kinase B1-1
- Os05g0483801 protein
- Os05g0484000 protein
- Cyclin-dependent kinase B2-1
Sequence:
MARGVSYVSAAQLVPMLRDPRIAVVDVRDEERIYDAHIAGSHHYASDSFGERLPELAQATKGKETLVFHCALSKVRGPSCAQMYLDYLSEADEDSDVKNIMVLERGFNGWELSGRPVCRCKDAPCKGVCS
Protein: NF-kappa-B-activating protein C-terminal domain-containing protein (Q389L6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Pre-mRNA-splicing factor SLU7
- MI domain-containing protein
- Peptidyl-prolyl cis-trans isomerase
- Peptidyl-prolyl cis-trans isomerase
- RNA helicase
- Pre-mRNA splicing factor ATP-dependent RNA helicase, putative
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MEPRGRELEKVVHSVIAQNIFCTHHTLAVHELSALGKRGSLPGQSRPQRTCTVNGRGDGTRTGESPLSETVAFLVRSSGVGYDAEGESPSAGEVSAASPSPCDDHHEPEVATSTAHEVRRVDAAGVSPTPSALAALIEAARARETVEGVGPIKTDSGVCHVMCPAPPRSGGATADGECRGLRVGAQTGDDGGDEFGVSLQQGNEPDYSKTEEPRGCVAASKHPLQMTREEFLAQYKRAPRRGEIGYDAESVAAAESLGYVMSGSRNREKQHYVDSIQQKLHEKEARKLRLQFRKVEDERNDSATVETLLTLMRQRTVGEVKKL
Protein: Translocon component PTEX150 (Q8ILA1)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Heat shock protein 101
- Exported protein 2
- Translocon component PTEX88
- Thioredoxin 2
Sequence:
MRIIILALLIVCTIINYYCAVQNNGNKSLNVMPTCSMPGNDSDSNDNETGDVDNDKNNELGNANDNNEMNNENAESKNMQGENSNNQEQLNENVHANDDAMYEGTPSSDNPPQENVDANNNEQEYGPPQEEPVSENNVENVEVATDDSGNDNINNNDNFNNNDNYNDNDNFNEEPPSDDGNKNEDELTEGNQSDDKPMNEEEATINEMGKITNPFEDMLKGKVDDMDIGKMMNKDNLQSFLSSLTGNKDGSGKNPLSDMMNIFGVPQTGKEGAEGGVNKENQMKQINELKDKLETMLKGAGVNVDKIKDSIKNNDLLKNKQLLKEAISKLTLDPSMMNMLNNKDGANGKPFDINPDSMMKMFNALSNENGNLDDLKMKPTDGSFDSFNDGVDNNLVPSNPKGQNNNEEDDEEGGDDDDYDDKSFVVNSKYADNSFEDKFNTFDEKDDDVKYELFGENEEAEELNNNTTTASSKGDANNSVNTQEGEGEEESFSANEENINNNNNHNNKNYNNYNTSQQEEDDNSFNENDEPLISSSQFDNNKKNKMSVSTHNKKSKNLMDSLDLESTNYGSNSSSSMSNNYNSKNKNSKKNNKKKSSQKDYIRTDGKVSFDMATLQKTIKNFGGADNEIVQNILKKYVTIDNDDDNDADEDEDEDDDDDDDLDEDEFSVKDIKKLIEEGILDYEDLTENELRKLAKPDDNFYELSPYASDEKDLSLNETSGLTNEQLKNFLGQNGTYHMSYDSKSIDYAKQKKSEKKEDQQEDDDGFYDAYKQIKNSYDGIPNNFNHEAPQLIGNNYVFTSIYDTKENLIKFLKKNSEYDLYDDDDKEGGNFKSPLYDKYGGKLQKFKRQRAFNILKQWRAKEKKLKEKKKKEEMEENKEFDFSKNYNFSSKNDGGVTMFSKDQLEDMVKNFGGKPSAHVTDSFSRKENPFVPTNTKNNSNDDDDMDNGYVTFDGKNKVSENDDDEKGNNNDDENDNDDSNDEEELDEEEDDN
Protein: Photosystem I assembly protein Ycf3 (P12203)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00439}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00439}.
Interaction partners:
- Photosystem I iron-sulfur center
- Photosystem I P700 chlorophyll a apoprotein A1
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I reaction center subunit II
- Photosystem I iron-sulfur center
- NAD
- Photosystem I reaction center subunit III
- Os07g0435300 protein
- DNA-directed RNA polymerase subunit beta'
- Cytochrome b6-f complex subunit 4
Sequence:
MPRSRINGNFIDKTFSIVANILLRIIPTTSGEKRAFTYYRDGMLAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAILQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITKRFEFE
Protein: Tetratricopeptide repeat domain 39A (F8W961)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAFLTTWKEAASGKSDRRTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQGSSHGGAVRPRAL
Protein: Uncharacterized protein (C8V9G3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- glutathione transferase
- Glutathione hydrolase
- Glutathione S-transferase, putative
- Mitochondrial peroxiredoxin
- Uncharacterized protein
- glutathione transferase
- Glutathione reductase
- Calcium/calmodulin-dependent protein kinase, putative
- Gamma-glutamyltranspeptidase
- glutathione-specific gamma-glutamylcyclotransferase
Sequence:
MSGVTPALRLLKGCFSQFSFNSNLRIPLKHSQLLNSASSRPYNRLFSTTSPVMSRPDITLYTAQTPNGIKISIALEELGIPYKVEKIDISKNVQKEPWFLEINPNGRIPALTDTFTDGQKIRLFESGSILTYLAEQYDKDYKISYPRGTREYYETISWLYFQNAGVGPMQGQANHFSRYAPERIEYGVNRYVNETRRLYGVLDKHLANSKSGYLVGDHITIADISHWGWVAAAGWAGVDIDEFPHLKAWEERLAAREGVEKGRHVPSPHTIKDLLKDKKKAEEIAAQGRAWVQEGMKNDAAK
Protein: Anon1A3 (Q9U4R5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
GVENLPSVAEAKQNHVDEVKPISEEPGNSSEEVPKAEEPLKSSGETSENGAATETAAAPKEPASVMDVDEDETLVENIPSANKEKALDDEKEPEQKSEEHAAAVLESKEQNEPAKEPTPEPMEVDGSSKGSSDTAQVDTPAIENVSAAPETEAAAKTTESSNDVVEVATEGKETVLEVPAAEPKEAESTVESAEELTETSTVVVTEPKEAASSEEEPSKVVDSAEPKEAESNTDESATPVPIDVSTAPASNDVSKPLEIDTTLVKTADSPAKEPQEICEVKKAEINVNGEPKIVNSSAEVGENAAPKVCN
Protein: Uncharacterized protein (Q387T6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSLGCDQHTHNRFNGPTEHSASSHGMPSEAGEKRYAAVHDAQPIQGSGKPADSSESHDQAPYPGPNLGLVTEAMTMERAVRVPRALRAATRRTMLDVLGHLHLTGCREAHNHRANATSWQDYAPQRQQWEHQIARDTRTEHHGSDEKEGTIRQPPKDLSRSLLHLLPPRRSEVSGGCFGFSTNSRDYGDGIPPYDSTAGPDDVRPKWRQGMANAAEREQSDRRVERQQSKQRSLLSILEESDSEPKHNARQKSGRQFNELGNVAQKRGRCCPLDMDLEDPRDSAGKPVKRATSSWGRWEGNDLIEPAHSIAGSGPPATRPNRVEVLLDDGTLGRGSVFTRSSTGSTASGRGEGRHSLADILATDDADDRFRATNTVERPEVTAGRAKGSAAIRRLAGNPTAERVIAYLTRSFNEWKLSRSLSHAPKRNDETYPITGATCSSAMPQGSGTVRVHLGFLVSKVECAFSLYMLRGRIVWADEKVKREIESDNFRSCFTGLRSDEQGDFLEQQQRGIATNIEWTIVLTTDAFRPNVVSSGKNIYLSRPFFVYPAAHVIVSSLNITTDAAQMPNGQHTKRHHFESGDGFGESCSDKNRNHTDHAKGAATTDTITPDRRHTVSHAFSTDPSPSWVYDPLVREVKNRTPTGSSHGMICGREQGRTTVMRLGPHIGLHPCGEGADSTKKPSHSAASDALHTDVENDPVGAGFPRGPGEEWEVPLELLLSLRCQIADNILSPSPKTSQGWGGEAILAEGHSSDSQFLTPPRSQLRLSSSLSSLLTPDGC
Protein: Protein SFI1 homolog (hSFI1) (A8K8P3)
Organism: Homo sapiens (Human)
Function: Plays a role in the dynamic structure of centrosome-associated contractile fibers via its interaction with CETN2.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:14504268, ECO:0000269|PubMed:16956364, ECO:0000269|PubMed:37934472}. Note=Localized close to the centriole. Localizes to the distal end of centrioles. {ECO:0000269|PubMed:37934472}.
Interaction partners:
- Centrin-2
- Centrin-3
- Centrin-1
- Serine/threonine-protein kinase PLK1
Sequence:
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
Protein: Acyl-lipid omega-3 desaturase (cytochrome b5), endoplasmic reticulum (EC 1.14.19.25) (Omega-3 fatty acid desaturase 3, endoplasmic reticulum) (P48623)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Microsomal (ER) omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine and, possibly, other phospholipids.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:8029334}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- 3-ketoacyl-CoA synthase 18
- Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic
- Oleoyl-acyl carrier protein thioesterase 1, chloroplastic
- Palmitoyl-acyl carrier protein thioesterase, chloroplastic
- Phospholipid:diacylglycerol acyltransferase 1
- Stearoyl-[acyl-carrier-protein] 9-desaturase 7, chloroplastic
- Diacylglycerol O-acyltransferase 3
- Fatty acid desaturase 4, chloroplastic
- Beta-ketoacyl-[acyl-carrier-protein] synthase III, chloroplastic
- Ethylene-responsive transcription factor WRI1
Sequence:
MVVAMDQRTNVNGDPGAGDRKKEERFDPSAQPPFKIGDIRAAIPKHCWVKSPLRSMSYVVRDIIAVAALAIAAVYVDSWFLWPLYWAAQGTLFWAIFVLGHDCGHGSFSDIPLLNSVVGHILHSFILVPYHGWRISHRTHHQNHGHVENDESWVPLPERVYKKLPHSTRMLRYTVPLPMLAYPLYLCYRSPGKEGSHFNPYSSLFAPSERKLIATSTTCWSIMFVSLIALSFVFGPLAVLKVYGVPYIIFVMWLDAVTYLHHHGHDEKLPWYRGKEWSYLRGGLTTIDRDYGIFNNIHHDIGTHVIHHLFPQIPHYHLVDATKAAKHVLGRYYREPKTSGAIPIHLVESLVASIKKDHYVSDTGDIVFYETDPDLYVYASDKSKIN
Protein: Ferric uptake regulation protein (G3LTY9)
Organism: Edwardsiella tarda
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU364037}.
Interaction partners:
Sequence:
MYKKLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDESIEKRQREIAKKHGIQLTNHSLYLYGHCAEGDCRSDEALHDEKA
Protein: Mitochondrial phosphate carrier protein 2 (Phosphate transport protein 2) (PTP 2) (Pi carrier isoform 2) (mPic 2) (P40035)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transport of phosphate groups from the cytosol to the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:14756774}; Multi-pass membrane protein {ECO:0000269|PubMed:14756774}.
Interaction partners:
- ADP,ATP carrier protein 2
- Cytochrome c oxidase assembly protein COX11
- Protein SCO1
Sequence:
MESNKQPRKIQLYTKEFYATCTLGGIIACGPTHSSITPLDLVKCRLQVNPKLYTSNLQGFRKIIANEGWKKVYTGFGATFVGYSLQGAGKYGGYEYFKHLYSSWLSPGVTVYLMASATAEFLADIMLCPFEAIKVKQQTTMPPFCNNVVDGWKKMYAESGGMKAFYKGIVPLWCRQIPYTMCKFTSFEKIVQKIYSVLPKKKEEMNALQQISVSFVGGYLAGILCAAVSHPADVMVSKINSERKANESMSVASKRIYQKIGFTGLWNGLMVRIVMIGTLTSFQWLIYDSFKAYVGLPTTG
Protein: Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase) (B5XKM7)
Organism: Streptococcus pyogenes serotype M49 (strain NZ131)
Function: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00318}. Secreted {ECO:0000255|HAMAP-Rule:MF_00318}. Cell surface {ECO:0000255|HAMAP-Rule:MF_00318, ECO:0000305|PubMed:9603964}. Secreted, cell wall {ECO:0000269|PubMed:9603964}. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface (Probable) (PubMed:9603964). {ECO:0000255|HAMAP-Rule:MF_00318, ECO:0000305|PubMed:9603964}.
Interaction partners:
Sequence:
MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK
Protein: tissue kallikrein (EC 3.4.21.35) (G3V8H1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MWFLILFLDLSLGQIDAAPPGQSRVIGGYKCEKNSQPWQVALYSFSKYLCGGVLIDPSWVITAAHCSSNNYQVWLGRNNLLEDEPFAQHRLVSQSFPHPDYKPFLMRNHTRKPGDDHSNDLMLLHLSQPADITDGVKVIDLPTEEPKVGSTCLASGWGSTKPLIWEFPDDLQCVNIHLLSNEKCIKAYKEKVTDLMLCAGELEGGKDTCTGDSGGPLLCDGVLQGITSWGSVPCAKTNMPAIYTKLIKFTSWIKEVMKENP
Protein: U6 snRNA-associated Sm-like protein LSm8p (D6XD86)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm4
- Uncharacterized protein
- U6 snRNA-associated Sm-like protein LSm7p
- U5 small nuclear ribonucleoprotein component, putative
- PRP1 splicing factor N-terminal domain-containing protein
- PRP8 protein homologue
- Small nuclear ribonucleoprotein Sm D2
- Sm protein B
- Small nuclear ribonucleoprotein SmD1
- Sm protein G
Sequence:
MLSQYLRRRVSVVTVDGRYLVGVLHAADQLMNLVLTSCAERVFDDEAEDSTDPNDIKNNRNGTNGATPPGGEMREHSLGVLMIRGSDVVCVASVNTVEEAKLSRKLWRGRNLPVVERVARSATASVKGG
Protein: Prostatic acid phosphatase (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Acid phosphatase 3) (Ecto-5'-nucleotidase) (Fluoride-resistant acid phosphatase) (FRAP) (Protein tyrosine phosphatase ACP3) (EC 3.1.3.48) (Thiamine monophosphatase) (TMPase) (P20646)
Organism: Rattus norvegicus (Rat)
Function: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
Subcellular location: [Isoform 1]: Secreted {ECO:0000250|UniProtKB:P15309}.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane {ECO:0000250|UniProtKB:P15309}; Single-pass type I membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000250|UniProtKB:P15309}; Single-pass type I membrane protein {ECO:0000255}. Note=Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles. Colocalizes with LAMP2 on the lysosome membrane. {ECO:0000250|UniProtKB:P15309}.
Interaction partners:
Sequence:
MRAVPLHLVGTASLTLGFLLLLSLRLDPGQAKELKFVTLVFRHGDRGPIETFPNDPIKESSWPQGFGQLTKWGMGQHYELGSYIRRRYGRFLNNSYKHDQVYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWQPIPVHTVSLSEDRLLYLPFRDCPRFQELKSETLKSEEFLKRLQPYKSFIDTLPSLSGFEDQDLFEIWSRLYDPLYCESVHNFTLPTWATEDAMTKLKELSELSLLSLYGIHKQKEKSRLQGGVLVNEILKNMKLATQPQKARKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHIMELYQDNGGHFVEMYYRNETQNEPYPLTLPGCTHSCPLEKFAELLDPVIPQDWATECMGTSNHQASL
Protein: Mucolipin TRP cation channel 1 (D3ZRF9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Endosome membrane {ECO:0000256|ARBA:ARBA00004337}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004337}.
Interaction partners:
- Mucolipin 2
- Mucolipin 3.
- Transcription factor EB
Sequence:
MATAAGRRGSETEQLLTPNPGYGTQAGTSPAPTTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDGSDDTFAAYTREQLYQAIFYAVDQYLTLPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSTSYKNITLKFHKLINVTIHFQLKTINLQSLINNEIPDCYTFSILITFDNKAHSGRIPIRLETQTHIQECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHKYNTHESLYQGRTTGACPYLPIQLSPAVILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYIEQCQDSPTSGKFRRGSGSTCSLLCCCGRNSPEDHSLLVN
Protein: 1-phosphatidylinositol-3-phosphate 5-kinase (EC 2.7.1.150) (B2KTE3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAADDKASSSSSVMDWSSEPPPSPTSPSHLTHFKPLTPEQDEPPLRSAYSSFVSLFRFNKEKTGANIAPAKKLAKLEEGRPPSVTEKSQSASSSPQGPRRNWSSPSHSIHGSETHRKHPELLRRTSAASEGRRKSEAPLGSHDPRTAVQLRTALKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCNEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSSSIGEDLSALSDSPCSVCVLEPTEPRTPVGGRKASRNIFLEEDLAWQSHQESQNSGLNSRLTVVQEDIGKSPARKRSASVTNLSLDRSGSSMVPAYESSVSPQNSRALPKTDHSEEERKILLDSFQLKDIWKKICHNTTGMEFQDHRYWLRTYPNCIVGKELVNWLLRNGTISTRAQAIAIGQALVDGRWLDCVTHHDQIFRDEYALYRPLQSTEFSETPSPDSDSVNSLEGHSEPSWFKDIKFDDSDTEQLADENDYVTPSSSSPSKRTSVSSFHSAVDSDSAASISLNMEQDNVNFHIKKQAKYPHVPPYPAEQKMEVLLSEDGGQHISISDAFIKESLFNRRVEEKAKEMLFTPLGWHHSSLDQLREENGEKKAMERLLSANHSHMMALLQQLLYSESLSLSWRDIIVPVVRQVVQTVRPDVRSCDDDMDIRQFVHIKKIPGGKKFDSAVVNGFVCTKNIAHKKMNSYIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPNLVLVEKTVSRIAQDMLLEHGIAIVINVKPQVLDRVSRMTQGDLVISMDQLLTKPRLGTCHKFYLHSFQLPNSEVKTLMFFEGCPPQLGCTIKLRGASEYELARVKEIIIFMVCVAYHSQLEISFLMDEFAMPPSLAESSSFPCLLESTTLREEDETSGERESQDNDESTLGDDNLTLVPGDDFETGFTGTIKAHSREPSTSESSHKDGESPRINKNASITSFSGGEEENIKTSTPLSSFSSTFPQPVTPPFLISDVKEMSQEVVKGSGEGEKNKYLESTLVHQDSTSSETSLPPTRLFRDPLQDDTGLFVTEHVASSDDRLKSISALFKQELKDIILCISPFITFREPFLLTPAGLRCPSRDYFPEQVYLSPLLNKDSKELDGRRKRQLLKESSPGSGSLTNGSVSHQRAIQILPCHKLTSARIAEQVGSSQQLARMLADYRAQGGRIRQREGTQFREAPPPKAPIKADSEEDKGAGVIDMTWSTKLDCLNPINHQRLCVLFSSSSAQSNNAPNPCVSPWIVTMEFYGKNDLTLGVFLERYCFRPSYQCPSMYCETPMVHHIRRFVHGKGCVQIVLKELDSPVPGYQHTILNYSWCRICKQVTPVVPLSNDSWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHKDYHQYFSYNQMVASFSYIPVRLLEICLPPPKIIIRNQGPSKSSLQQDLKDFSQKVAQVYLAIDDRLTSLKTDTFSKTREEKMEDMFAQKDMEESELRGWIEKLQVRLQTSVIDSSQQLQAVLESVVVKKQGLCETLQSWNNRLQELFQQEKGRKRLSVPPSPGRHRQPTTDESKTSALESSPRNPSPVVPNGDKEDRHLNTFPSSSGSSSLLQLPSPAEQPSDVITSGPSFPDQDSVSNPEDMFDGHLLGSNDSQVKEKSTMKTILANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEREPSSIIAFALSCKEYKTALEELTKTTAKTGGDDTSQTISAGESRVKNSPAKPSDNSMSQLSRSSVDADPLKEPESADKQKKQTGNPHIELQFSDANAKFYCRIYYAEEFHKMREEIMESTEDDFVRSLSHCVNWQARGGKSGAVFYATEDDRFILKQMPRLEVQSFLDFAPHYFTYITGAVHLKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDQGKESCEVVLLDENLLKLVHDNPLYIRSHCKAILRAAIHSDALFLSSHLIIDYSLLVGRDDSTDELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWSGLGLNC
Protein: Adenosine A2b receptor (Adenosine receptor A2b) (Q29ST4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU201114}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU201114}.
Interaction partners:
- Adenosine receptor A2
- Adenosine A2a receptor b.
- Guanine nucleotide-binding protein G
- Uncharacterized protein.
Sequence:
MDSLYIAIELVIAVLSIAGNVLVCWAVAINSTLKNATNYFLVSLAVADILVGCLAIPFAITISIGLWSDFYGCLFLACFVLVLTQSSIFSLLAVAIDRYLAVKIPLRYRELVTGKRAREIITILWILSFIIGLIPFVGWNRKDLACSRNKSGSLQTSNSSDDDAAETETGFLQSCYLECFFEKVVDMSYMVYFNFFGCVLPPLLIMLGIYAKIFTVARKQLRQIELKCSVSNGENQHHGLLQREIRAAKSLSIIVGLFALCWLPVHILNCLTLFYSELKKPSFIMNIAIILSHANSAVNPIIYAYRIREFRVTFRKILNRHILCQRDELYRSSNGSSSNRDQITMTIDPLL
Protein: Transcriptional regulatory protein CpxR (Q7VLH6)
Organism: Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- histidine kinase
Sequence:
MPRILLVDDDLELTELLAELLSLEGFHIHCVHNGQDALTELELQSYDLILLDVMMPILNGIETLKQLRQKYAIPVLMLSARDDEIDRVLGLELGADDYLPKPFNDRELVARIKAILRRTVAPNLSDVVTPSNHSPEDSNKQLSFGGVELHPGRQQAIFEDQDLDLTGTEFALLQMLMHNPGQILSRELLSLEVLGKRLTPYDRAIDMHISNLRKKLPERNDNLPWFKTLRGRGYLLVTEK
Protein: Glutathione S-transferase (EC 2.5.1.18) (GST class-alpha) (Q08392)
Organism: Gallus gallus (Chicken)
Function: Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
Interaction partners:
- Glutathione reductase
- Glutathione peroxidase
- Cytochrome P450 family 1 subfamily B member 1
- Uncharacterized protein.
- Peroxiredoxin-6
- Glutathione S-transferase theta-1
- Glutathione synthetase.
- Cytochrome P450 1A5
- Glutathione S-transferase 2
- Thioredoxin domain-containing protein.
Sequence:
MSGKPVLHYANTRGRMESVRWLLAAAGVEFEEKFLEKKEDLQKLKSDGSLLFQQVPMVEIDGMKMVQTRAILNYIAGKYNLYGKDLKERALIDMYVEGLADLYELIMMNVVQPADKKEEHLANALDKAANRYFPVFEKVLKDHGHDFLVGNKLSRADVHLLETILAVEESKPDALAKFPLLQSFKARTSNIPNIKKFLQPGSQRKPRLEEKDIPRLMAIFH
Protein: protein kinase C (EC 2.7.11.13) (G5EGE3)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Ras-like GTP-binding protein rhoA
- PDZ and LIM domain protein Zasp
- Zinc finger protein unc-98
Sequence:
MDYHSNGNGINGMNGSSRHSADGPSTPTHSGNGHSNGEGNRYALSAHRNVVKPLGSNFGASGSATTSTPKSVISSLTSACNNSPVLSFTRGVLRASRKKIRPLFSTFSTSSNTGYYRFESPSSSLNAYYPQESFNGPILKMITCTESPPRSLDVLKRSKSTYWETAPAEMVELADKYNFTINEGSSIQQEALELRSVIRKDLTKKLKIKSGYSRIKLITSDRRQSEFLRYELSDLNEQIADLQEDLQALEMYNSGAFDEDVMYLDNLEDCDVENGPPSKLVILQLELEKELKVKRGLEQFLRGAPDKSKVHGDSQSLLDDSRAKIAMLRMQIERLSQEAPAVEGEPKTKVELAIDDLIIRFHKEKLIMDGSRNMIRILRSKRKPDSKAVDEAMNSYVIASEKADLIKLALLKYASSLPLEHDHRKYLIGEINSGLIPKPPSLSQDRNSPSSEDGGNGTSTSRRCSFMPYSLQISGCLEVTINGCAGILSEVFERKIRKDVPGVPGFISVYGMDASGKKKKSARGPNSSEEVFCVLRIDNRFIGATELRKIVDRNWDQKFDVDLDRSRELQIELFYHDDRSMCGFAAVKLSNLIETSSKVGIIVPVEPQGNIFVQFKYMNPVVSRKPKLERQRRLFRVKESNDGARQKLGVFAFSRLIKNRGNEPSEKFAAFTGFTPMPSSSSQHQPGTSSSGPSTSSSIASTPTPSTSNSLFDKSFNPRKSAKKREAREAAAVAPMTAAVAAVNLNAPSTSNSMQPSTQERNLVVDEFPTDRSGPSQAPPVPAVRHIDFFASSDGAPLTVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDVFDEVRGCFYAACVVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLEFTQEKARFSAASSTRPITEADQRLFNNFDFSIVP
Protein: Coronin (B5X7W3)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MSRKVVRASKFRHVFGQGVKADQCYDDIRISQMTWDSNFCSVNPKFVAMIVDASGGGAFLVLPLNKTGRIDMSQPTVCGHTGPVLDIEFCPHNDNIIASGSEDCSVMIWEIPEGGLVTPLKDPVVKLEGHSKRVGILSWHPTAHNVLMRLPMFTTCPCTAVRRVRRAWATCPRGAWRSTSVKSPGFTSSMRGSVSPLS