wanglab/gogpt-training-data huggingface dataset:
Protein: Axin-1 (Axis inhibition protein 1) (A0A0S2Z4M1)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
Protein: F-actin-capping protein subunit beta (CapZ beta) (P47757)
Organism: Mus musculus (Mouse)
Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A9XFX6}.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Cytoplasm, myofibril, sarcomere {ECO:0000250}. Note=In cardiac muscle, isoform 1 is located at Z-disks of sarcomeres while isoform 2 is enriched at intercalated disks. {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm, cytoskeleton, perinuclear theca, calyx {ECO:0000250|UniProtKB:P79136}. Note=Isoform 3 is located to sperm head cytoskeletal structure tightly associated to the nucleus (By similarity). Isoform 3 colocalizes with the alpha subunit in testicular sperm and to the acrosome in elongating and condensing spermatids. {ECO:0000250|UniProtKB:P79136}.
Interaction partners:
- F-actin-capping protein subunit alpha-1
- F-actin-capping protein subunit alpha-2
- F-actin-capping protein subunit alpha-3
- F-actin-capping protein subunit alpha
- Dynactin subunit 4
- Dynactin subunit 1
- Twinfilin-1
- Dynactin subunit 2
- Twinfilin-2
- Dynactin subunit 6
Sequence:
MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFKQLQRELSQVLTQRQVYIQPDN
Protein: Minor structural protein 3 (Q9AYV6)
Organism: Lactococcus phage Tuc2009 (Lactococcus lactis bacteriophage Tuc2009)
Interaction partners:
Sequence:
MSNILFLDKMQQVIKSYDSDEFIECVQTKEITTNASELMNDTLSVSLPFDETIKDASYIAVNDTKEQEFTLYRILTTKDEDNSLSFEAINFAVDELDNFIIKDIRPKNRSFSYVINQLLSDSGCDWVLGVCEPTKTVSSTFYYTSMREALKALQELGAEFTFSIEITGNKITKKIVHCYNQIGKITNKRFEYGEEVLKIVHQQDRTNIVTALIGRGKGEEVGDGYGRRIEFSDVEWKKSNGKPLDKPKGQNWIEYPEMTKEYGIPSNGKMLPRKTVVVFDDVEDASELLQKTYDQLAYYCRPLVQFSTEILGSDSIGNTVSIHRGDRNYHYQTRVFKVVTDHVNGRVQASLGDNLSGNSINRQLSQVQSNISDLDNNKMTFYDSTEIGKYQSDIIRGAKGGSIMMMNPSDLGKGESREPFQMVWMNGPSIEESDHFLVANSEGIGFIDGNFNLDNFKMAWTIDGIFNADFINAGTLQGVKIRSVHKDFIIELDQGKIRFIKRNGSSENEMFAFAPTYTGGQLQGINAIQNHGYSFALSSKGNNGALLNVLEIPKDSTAENRKLNLYGEVKVDGNFYVNGVKIDKNGGSSGGGDNGWNGQYPPEVTTDRDKRYWQIWAMAIGAGFSKQAAAALLGNEQGESDANPTADEGGGRPGFGYGVWQWTDSSGASSGRVYMINLMTRAGVTDNPDTITAQFKLLMWHAQNGQWIAKSSYPYSWTQFMTLTNINTATQAFVANFERPLNGHPERSTWAQEWYNKFVNLGIPSGSGGYIAPISRPITVTSEMGWRTSPITGAQEFHNAMDLVNGNPTTPILASNDGQVVQAGSNYYNWYGNYTVIKHADGLYTGYAHQSRIDVSVGQNVKKGQQIGLMGATGPVTGPHLHFQFMDQYWPSSHAHFKNPRDYIKF
Protein: Hydrophobic dipeptide epimerase (EC 5.1.1.-) (F7ZLS5)
Organism: Roseobacter litoralis (strain ATCC 49566 / DSM 6996 / JCM 21268 / NBRC 15278 / OCh 149)
Function: Dipeptide epimerase with a preference for hydrophobic substrates. Catalyzes the epimerization of L-Ala-L-Thr, L-Ala-L-Met, L-Ala-L-His, L-Ala-L-Phe, L-Ala-L-Tyr, L-Ala-L-Trp, L-Ile-L-Ala, L-Ile-L-Ser, L-Ile-L-Met, L-Ile-L-His, L-Ile-L-Phe, L-Ile-L-Tyr, L-Ile-L-Trp, L-Phe-L-Met, L-Phe-L-His, L-Phe-L-Phe, L-Phe-L-Tyr, L-Phe-L-Trp, L-Phe-L-Ser, L-Phe-L-Thr and L-Phe-L-Lys (in vitro).
Interaction partners:
- DUF1611 domain-containing protein
Sequence:
MKVEYHTVYLKKRFPLRISRGVFEGSDNLYISLTENGHTGWGEMAPGGTEGAETAAAGQAMLEQFCATGLSASIHDTWQNAHAAGVAPCALAALDMALWDLRAKQAGVPLYALLGLARRAVVSSVTVGINPPDVVRERVPLLLARGARALKIKLGSPEGIEADQAMFAAVFEAAQGSGAVLRVDANGGWSLKDARRMMGWLAEHDVEYIEQPLVRGAEDQLPDLFKDRAMPIFVDESCRMSGDIATFFQSVDGVNLKLMKCGGITEALRIVATARAFGLKTMIGCMGESSVSIAAGASIGALFDYIDLDSHLNLDPDPATGAPFENGITLPADQPGHGGVLSHA
Protein: Transcription factor MYB113 (Myb-related protein 113) (AtMYB113) (Q9FNV9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator, when associated with BHLH002/EGL3/MYC146, BHLH012/MYC1, or BHLH042/TT8.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
- Transcription factor TT8
- Transcription factor GLABRA 3
- Protein TRANSPARENT TESTA GLABRA 1
- Transcription factor EGL1
- Dihydroflavonol 4-reductase
- Anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase
- Leucoanthocyanidin dioxygenase
- Naringenin,2-oxoglutarate 3-dioxygenase
- Flavonoid 3'-monooxygenase
- Transcription factor MYB114
Sequence:
MGESPKGLRKGTWTTEEDILLRQCIDKYGEGKWHRVPLRTGLNRCRKSCRLRWLNYLKPSIKRGKLCSDEVDLVLRLHKLLGNRWSLIAGRLPGRTANDVKNYWNTHLSKKHDERCCKTKMINKNITSHPTSSAQKIDVLKPRPRSFSDKNSCNDVNILPKVDVVPLHLGLNNNYVCESSITCNKDEQKDKLININLLDGDNMWWESLLEADVLGPEATETAKGVTLPLDFEQIWARFDEETLELN
Protein: Microtubule protein alp7 (Altered polarity protein 7) (Transforming acidic coiled-coil protein mia1) (TACC protein mia1) (Q9URY2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for bipolar spindle formation and proper chromosome segregation. Has an indirect role in connecting the kinetochores and the plus end of pole to chromosome microtubules by targeting alp14 to the spindle pole body. Involved in the emergence of large microtubule organizing centers (MTOC) in interphase cells. Attaches to the minus ends of microtubules and associates with the sites of microtubule attachment on the nuclear envelope. This leads to the stabilzation of the microtubule bundles.
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associated with the equatorial MTOC, spindle midzones, spindle pole body and mitotic kinetochore periphery. Spindle and kinetochore localization is alp14-dependent.
Interaction partners:
- Spindle pole body component alp14
- Kinetochore protein ndc80
- Kinetochore protein nsk1
- Phosphoprotein p93
- DASH complex subunit DAD5
- DASH complex subunit ask1
- DASH complex subunit dad2
- DASH complex subunit spc19
- DASH complex subunit spc34
- DASH complex subunit dam1
Sequence:
MSDIVSSSTDYSRRSPSSSSIGTNETDHTGFHEKRQGASSESLIPPAQRSSEESMPAPKLFPKLTSKPNPQLNLKDTLNKRVSDRLQALELNKSFDFSGTPRPMHPISHPLSQHKTPEFKHRKRNVESILTPKNPSLFSSSNAASQRGSLNTAPSNFAYSHSSSLQTSASSRPPVLSNGSFPRQTNTAPLNPPVHLKDNIRNSATPSTSQADIPTQYPINSTQKQQAKYEAEIEGYKAKLAGTYHEISVLQNTIVNVSGQLIAVNDQLQQLRSGKASTSPSTKDTNMRLVEGHNEETLALQRGKYTQEEVDKLIQERMEKVAEDLHAQYSAKHTQKINAFKANYARKYEATIQELQNQIGTAPNAPKISNSNWEEERRALKADNQTLQKQLEKAIQERQDMSDFLNNFKADMAKSDKLLMQQQSQQTGDLETLRLQLQALQEELRVEREERQQLIQMSEDLVIAMDQLNLEQKS
Protein: Small ribosomal subunit protein uS12m (37S ribosomal protein S12, mitochondrial) (P53732)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. uS12m is required for respiratory growth.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823961}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Small ribosomal subunit protein mS33
- Large ribosomal subunit protein bL32m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS10m
Sequence:
MLSRFMSNTWCTPLRQAQRLFSSTTTMQATLNQIKRGSGPPRRKKISTAPQLDQCPQRKGVVLRVMVLKPKKPNSAQRKACRVRLTNGNVVSAYIPGEGHDAQEHSIVYVRGGRCQDLPGVKYHVIRGAGDLSGVVNRISSRSKYGAKKPSKS
Protein: Probable small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG) (Q9VXE0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62308}. Nucleus {ECO:0000250|UniProtKB:P62308}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000250|UniProtKB:P62308}.
Interaction partners:
- Probable small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein F
- Small nuclear ribonucleoprotein-associated protein B
- Probable small nuclear ribonucleoprotein Sm D1
- Probable small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein Sm D3
- U1 small nuclear ribonucleoprotein 70 kDa
- U6 snRNA-associated Sm-like protein LSm8
- PHD finger-like domain-containing protein 5A
- U1 small nuclear ribonucleoprotein A
Sequence:
MSKAHPPEVKKYMDKRMMLKLNGGRAVTGILRGFDPFMNVVLDDTVEECKDNTKNNIGMVVIRGNSIVMVEALDRV
Protein: Immunoglobulin heavy constant gamma 2A (Ig gamma-2A chain C region, membrane-bound form) (P01865)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
KTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGLDLDDVCAEAQDGELDGLWTTITIFISLFLLSVCYSASVTLFKVKWIFSSVVELKQTISPDYRNMIGQGA
Protein: Toxin subunit YenC2 (B6A882)
Organism: Yersinia entomophaga
Function: Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae. The TC has an endochitinase activity (Probable).
Subcellular location: Secreted {ECO:0000269|PubMed:21278295}. Note=Secreted when grown at 25 degrees Celsius or less, but not when grown at 30 or 37 degrees Celsius. {ECO:0000269|PubMed:21278295}.
Interaction partners:
- Toxin subunit YenB
- Toxin subunit YenA2
- Toxin subunit YenA1
- Exotoxin
- Hypothetical protein
- Chitinase 1
Sequence:
MDIQLFSKTPSVTVFDNRGLSVRDIAYRRHPDTPKVTEECITYHQFDFRGFLAQSLDPRLNHKEVTNFSYLTDLNGNIIYTQSVDAGNTLVLNDTEGRSVIAMTNISRGENGKDDLSLAVTRTFQYENAPLPGRPLSVTEQVNGENARITEHFVYAGNTPQEKNLNLAGQCVSYYDAAGLIQTDSVSLTGKPLSVSRKLLKNLDDTNILADWQGNDTSAWNSLLATEIYTTVTRTDAAGAVLTTIDAVGNQQRVAFDIAGQLSASWLTLKGGQEQVIIKVLTYSAAGQKLREEGGNGVVTTYTYEAETQRLIGIKTERPNGHAAGAKVLQDLRYEYDPVGNVLSITNDAEETRFWRNQKVVPENAYRYDSLYQLVSASGREVAGAGQQGSDLPSPLVPLPSDSSVYTNYTRTYTYDSAGNLMRIRHSAPATNNNYTLNITVSERSNRGVMSSLTENPADVDALFTASGSQKCLQQGQSLIWTPRGELRTVLLVARGETADDSESYRYDGSSQRILKISSQQTNHSARVQRALYLPGLEWRTMTGGVAEAENLQVICIGEAGRAQVRVLHWESGKPDGIINDQIRWSYDNLTCSSGLEVDGDGLVISMEEYYPYGGTAVWAARSHIETAYKTVRYSGKERDATGLYYYGFRYYQPWAGRWLSADPAGTVDGLNLYRMVRNNPLRLTDPDGMAPLDWLDLDTTNASRDIVKAIYQLNQIDGPHRGVRDTYQRMTESTGMILQETLNNEAVLKGIKQKDKEKKSRGMKFTNSKLKTYAAHAGVLNTLQPDPVYKDGFLNLPGSLGNKNTFPGVELIEDKVKPSLSQYHPDKLGKSQRWKPESSLGYYRVADTEAFITGIRSQYKSSGTDLHAVVEGRIRDHLLANNNVLPKMAGIAGLHAEVQALNYIISNPDIEGGNAERLNGSYIFTQRLVGDVNQDFPACYNCSGIISGLENVMTGRVNNDVRLKRRKSF
Protein: Indoleamine 2,3-dioxygenase (EC 1.13.11.52) (A0A1D8PN08)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Kynureninase
- Kynurenine formamidase
- aromatic-amino-acid transaminase
- 3-hydroxyanthranilate 3,4-dioxygenase
- TauD/TfdA-like domain-containing protein
- Aldehyde dehydrogenase domain-containing protein
- Tryptophan synthase
- Kynurenine 3-monooxygenase
Sequence:
MTIPNIEEFDVFPNSGFLPSKLPLERLPQEYYQPWENIVNNLPSLILTKRIRAIIDKLPVLETTHLTSDEEYRRAYQILGFLAHAYIWGTDTPTDKLPSQIATPWIKVSDHLGLPPIATYASLCLWNFKQIMPSDDIWDLDNLTTINTFTGSIDESWFYLVSVYFEHKGALAITTGLDAIKCAYDNNTKGLVENLQQLAEAIDSLGSVLMKMEEMCDPHVFYFRIRPYLAGWKNMTEVGLKGVYYGEEKTVRNYAGGSNAQSSLIQFLDILLGVKHYSTGERPLPFKASTGVGAENGFMNEMREYMPGNHQKFLSKIQEITNINQYVLDHKDSHPELVLSYDACLAMLKSFRDKHIQIVTRYVVLQAKKTEKMGSSSTLRSGLARKKKEERGTGGTSLLPFLKQCRDETGDPAAGNWGQRILSDGVMRLKFSKPNGINED
Protein: Insulin receptor substrate 53 kDa, isoform D (A8JNR2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEAEEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQSGTGDIGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESYQKAVSTMKKQRKKKATPENTEKELRSLQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLERQCSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAAYESGYSTSNGHNNNNISSSSSSGNNNTSGNMRRLERIKDGDDDHLQGHGAQLKKSRSIDAPYGDMRTLHERENLSGLGGTGPAHYAQNSLPRAKSDFNLALVGTGQSSANKHKIIEEQLATLGDDQRGDQRPLVKALYAYMPSGENQLSFEEGDRIALVGGKAKGWQFGENLRTQHFGWFPVAYTNAEVAEVTTSGGRRYENMLMSYERNGGGSGSGSGGGGLRSYQQQQDYEAQLELMESHEATYRRRRNHSAEDSSPTRMFGDTIKQQKKYRPGSGANPRPGPPPTLPAPVPNGPQSQSSRMLNSSQSFCASNGGGVNAAVERRKQKLLNGVQSSKNHPSGKSGVAAKTSLHSSNDSGFANEPPPQPEVDYSDEEPATQRVAIRRGIYRNYSIDY
Protein: Dosage compensation protein dpy-30 (Protein dumpy-30) (Q10661)
Organism: Caenorhabditis elegans
Function: Essential for dosage compensation. Required for the sex-specific association of the dosage compensation complex proteins dpy-27 and dpy-26 with the hermaphrodite X chromosomes. Plays a role in developmental rate and body fat regulation downstream of the TOR complex 2. Required for the robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development.
Subcellular location: Nucleus {ECO:0000269|PubMed:7588066}.
Interaction partners:
- Retinoblastoma-binding protein homolog 5
- Set1/Ash2 histone methyltransferase complex subunit ash-2
- Nucleosome-remodeling factor subunit NURF301-like
- CXXC-type zinc finger protein 1
- Histone-lysine N-methyltransferase set-2
- Zinc finger protein sdc-3
- Lysine-specific demethylase 9
- Sex determination and dosage compensation protein sdc-2
- WD repeat-containing protein wdr-5.1
- WD_REPEATS_REGION domain-containing protein
Sequence:
MADQTASAEVATEKMDTAEAPAAAPAASAAAPAEAESNENTTVPSNVLSANGGQQTGNQSAPRNTSTVPTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFLLREKDRYNAENQNPAGQQ
Protein: Ribose import binding protein RbsB (P02925)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose. Also serves as the primary chemoreceptor for chemotaxis.
Subcellular location: Periplasm {ECO:0000269|PubMed:1583688}.
Interaction partners:
- Ribose import permease protein RbsC
- Ribose import ATP-binding protein RbsA
- D-ribose pyranase
- L-arabinose transport system permease protein AraH
- D-allose transport system permease protein AlsC
- Probable ABC transporter permease protein YphD
- Inner membrane ABC transporter permease protein YjfF
- Galactose/methyl galactoside import permease protein MglC
- Ribokinase
- Galactofuranose transporter permease protein YtfT
Sequence:
MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSLKDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKMANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGTSAARERGEGFQQAVAAHKFNVLASQPADFDRIKGLNVMQNLLTAHPDVQAVFAQNDEMALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKVLKGEKVQAKYPVDLKLVVKQ
Protein: Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2) (Q6IMI4)
Organism: Homo sapiens (Human)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P0CC03}.
Interaction partners:
Sequence:
MADKSKFIEYIDEALEKSKETALSHLFFTYQGIPYPITMCTSETFQALDTFEARHDDIVLASYPKCGSNWILHIVSELIYAVSKKKYKYPEFPVLECGDSEKYQRMKGFPSPRILATHLHYDKLPGSIFENKAKILVIFRNPKDTAVSFLHFHNDVPDIPSYGSWDEFFRQFMKGQVSWGRYFDFAINWNKHLDGDNVKFILYEDLKENLAAGIKQIAEFLGFFLTGEQIQTISVQSTFQAMRAKSQDTHGAVGPFLFRKGEVGDWKNLFSEIQNQEMDEKFKECLAGTSLGAKLKYESYCQG
Protein: GH17145p (Limpet, isoform L) (Q9VVB6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAAEETALTGVGELLFSLLIGYLGALEFAFVARHLYHWTFQHPGDSSVDAAADAEELPRMRERLDKQIKEAAEREALAGTNVMQDGVLYVNGIRVDPAGDKRQALAAELARQQQIEADTRRQLAEAEAKLVEERLRVQREKEESEEQQRKLVEAERQREREQAEKELQEQREAERRQLEAEENQRKQRENEEKERLENERRLIDAEREREENERRLQEAEEQREREESERRIVVAERQREQAEAEKERAEQQRILAEAEAAQAERRLFDAEIQRERDQADEEGQALRDAEIVERLLAAERELSPSATESELEEDAAIAEQSRRLISSRTDLEQKQRMIEENARRFLEAEEEMVMLQQRQLQASHSKEEADEYAGMEPVVEELCVKKVAPPRFQEPPEEPMVHKVKTQFGQGSGPEDAYSAKSKTLTFPGVSDEGSSLEPKTPFSIQQSSFSTQPSDEGNRIESERPEPEGEDQIQEVQYTEDYLRSLDGIKNRPLMREDGSGRRRAFKKRRSSGSSNSSRESRASRDEELKMFTSLEEEELRHGDREDYNPIKYTSEPTLRVKSHRRHKRSPAKDVRPTAESTTSLEMLGEESTNPWGEVVPEHYKDTEFWKREKALSIDEEEIELERPSRGEDVEEEATNEPKSSSFEEATEAQNEQAVAALKQQLSKEQLDKEAEKDNPQAVDTSDSNKSNT
Protein: Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) (Q0KHS0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|HAMAP-Rule:MF_03022}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03022}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|HAMAP-Rule:MF_03022}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000256|HAMAP-Rule:MF_03022}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|HAMAP-Rule:MF_03022}. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles. {ECO:0000256|HAMAP-Rule:MF_03022}.
Interaction partners:
- Katanin p60 ATPase-containing subunit A1
- Katanin p60 ATPase-containing subunit A1
- FI21292p1
- Patronin
- Spastin
- Large ribosomal subunit protein mL46
Sequence:
MALPRKLISKIYDIKAHDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQNECFMSLTGHNRSIDCVRFAYKDNFVYSADDIGIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLWDVQNENNCIKVCRGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIADPPVTAITCVQFHPFEFLLAAGRVDGTVSIYDLEHQQLVSQTTHFYGQAIRCITFSDNGECLFVGSSSGISVIGWEPDRELDHIKSTWSSLADMKVVNNKLICGCHEIDTVSINTISLDRVIPFYQPPNSLPNFKHNSTNRKSFTRGNQKFRLSVGGAKPAQVQEEHEGDKSGLSSPNYSLEVVNEAVLESAETSPMSSLPPVHLASMAGSSADLAPHHVVYGGAIDSALRQGKYSRVPDNMASYGSSYGAIDTRLMSLNEPSSLHKPDIYNLYPLDKNEEADVQQLEFNLNDSNPPILNNYDNYEMAEDFPVNQNLNYITNNYKPVPATSTINASSKSIKKTTTTTLHKRTTNNMAGAKQTSTGIFGGSKLSQVSSVSSMELHKLDDNMVLKKSSSSNVVNKNKRPMGSAQSQFSKENNQQKNINVEIITKPPMRSRTTLDMRTSHQAKTQEKQIHQQQPMNNRIIMDDHDFDMLSRSHEAVLQELSNRQSSLDLLRHATRSHDVLGALRQARSCGKSIFIDLLGAILEKPSSWNLDFCMFVLPEIYELLQSQHKFHFTRACDTLRIILSNFLPTIQENLDSWAANGLGVDVTREDRQRKCAECQRWLLQIKNLPESTHFGSTLSQLQNIIIF
Protein: ATP-dependent DNA helicase MER3 (EC 3.6.4.12) (Protein HFM1) (P51979)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-dependent ATPase. Required in the control of double strand breaks transition and crossover during meiosis. Unwinds DNA in the 3' TO 5' direction. Prefers single-stranded DNA.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- MutS protein homolog 4
- MutS protein homolog 5
- Sporulation-specific protein 22
- Pre-mRNA-splicing factor 8
- DNA mismatch repair protein MLH1
- Meiosis-specific protein SPO11
- Crossover junction endonuclease MUS81
- Pre-mRNA-splicing factor 6
- Meiotic recombination 1 protein
- Pre-mRNA-processing factor 17
Sequence:
MKTKFDRLGTGKRSRPSPNNIDFNDQSATFKRNKKNSRQPSFKVGLSYNSLLDDCDDENETEEIFEGRGLQFFDKDDNFSITADDTQVTSKLFDHDLEQTPDEEAKKPKKVTIRKSAKKCLSTTILPDSFRGVFKFTEFNKMQSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKNWFPSFVNLSVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVLVDEIHTIKEKRGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNNELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYSDLDVLQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAVNWLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVKVKIIDISNGEYKSTAYGNAMTRHYISFESMKQFINAKKFLSLQGILNLLATSEEFSVMRVRHNEKKLFKEINLSPLLKYPFLTEKKQSQIIDRVSQKVSLLIQYELGGLEFPSYEGASKLHQTLVQDKFLVFRHCFRLLKCMVDTFIEKSDGTSLKNTLFLLRSLNGHCWENTPMVLRQLKTIGLVSVRRLIRHGITNLEEMGHLSDTQIEYYLNLKIGNGIKIKNDISLLPCLNIRTKLENCKIENEELWLTFKVEISATFKSSIWHGQHLSLDIETEKSSGELIDFRRLQVNKLQSPRGFRISAKISPKLEKIEFSIHCQEIAGLGKTIVYSTDHLASQFSAKTPNIRKDLNSLEKCLFYESSSDGEVGKTSRVSHKDGLEESLSSDDSILDYLNERKKSSKAVESAAVIHPEAHSSSHFSNGRQVRSNGNYECFHSCKDKTQCRHLCCKEGIPVKYIKEKGPSSIKPVSKPDQIRQPLLAKNINTTPHLEKRLNSKPKQWQEENTDIATVHTLPSKIYNLSQQMSSMEAGEQVLKSGPENCPEIIPIDLESSDSYSSNTAASSISDPNGDLDFLGSDIEFE
Protein: Hapln1a protein (Hyaluronan and proteoglycan link protein 1a) (B3DIH3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MIALFSVALMVFASSLHVEAQDSESRVKVYANRGDNITLPCRLDGQSTLFGNRIKWTKIEDDSTETDVLISMGFHKKAYGSYQDRAYLLEVDDSDATLVITDLDVNDYGTYRCEFIDGMNDMTLEVDLEVQGVVFPYSPRLGRYNLNFQNAVAACQEQDAVVASFEQLYGEWKSGLDWCNAGWLSDGTVQYPITKPREPCGGARATAGLRNYGQRDKSNSRYDVFCFTAGLKGRFYYMIQPKKLNFDEAVDACKGDGAEIAKVGHMFAAWKLQGYDRCDAGWLADGSVRYPISRPRKNCSPTEAAVRFVGFPDKKQKLYGVYCYKAQQ