Protein: Dynein heavy chain at 89D, isoform B (Q9VAV5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}.
Interaction partners:
- Dynein light chain Tctex-type
- Dynein light intermediate chain
- Dynein light chain roadblock
- Dynein axonemal intermediate chain 4
- Dynactin subunit 2
- Kinesin heavy chain
- Lissencephaly-1 homolog
Sequence:
MSQTQFESTSDSADATAESLNNVEPRIVWLKTIMSNMLGVFEPKYVNATISKNMPAVENFFQRRYETQNDLDFVVLFFWRTFYDKLIEEEITVLEEVPRPPPTVPDKKGKGKKKGDARMAGGKSAGKAGASAGAAGKGRKKAGQDAAAPAGGDQEAVEEVNTGGETTDAEVEGELEGEEEATVAGSGKSSARSRPSSDTENGSKFRKKKATYVPVYVEVKKLVPAYVKTPQVHCHFGRMESCDLDPKIKYIYIVRKNRREIPNFSDVSACFAQMPLYFLLGTVRGSLINSLRDDLNLVYKSAIQFQFREPATADSQQMDSYEGQAGGSGGGGAGGPAGETGEDISSEAKESGPGLLELSKPSEFRLRALKQQKKMKEKEAAAKKAKAKKTDAEPTEEEEEADAHKVEAHLSSSEEEVEIKVEKLTIGQRWEKMLNETKAKVEAEHAAEEATPPRITPIQRRLLKEIEEFQSEITWTINHIVWAFSLPSSYILPGQEATEFEDAIIRVPVDPKRLDLVITYTQQQLEEVVDGWIKYLKKTMKTLTDAKLDDFTPMAEHRYWHKMEVELYGTLEQLKTEFVVAVLQRLTDDKSPVLDEWQAVVEKTEARFKLAKENSDYLGTIIDYLEKVRSYESFKMVVLQIPNIMVGLRHIWTMSSHYCRDPEMQVLLCQISNVFVQKVKSIINFENIFKYSATYTYETATNCANLLRCWKQAYKLSRQHIEDSGAGSRWEFDRVALFNEVNHIHRVAVDIAYVGRVFVQYENLFGHRLKACIADPSIVDNLMRKVYRMLDDLIKSVDYDMFRPGNWENWEYSLELFNKRLDNVENEAKNVIDQSINSLLSSEKGLDLVVNAMNIDTRATLQEFVATKHENLLRFFVTEINAVERVFTKLKKSPPMAKHQPAKISAIFWARLLGKKLKTSVLAFKRVEDEPAIKNSFLKRSSFKQYFELMTVMFQFEKVLFENFIQNATYLVNTTNRSNVLRIRICKESTMSYISEAVQTLKAKPRPELQMTSDRRVTPVKSSNLMPVQSEAFSAYSVADSAGTEISSESENEGLLVGDTSQKKLMCRINRLTVLVAMIMWMVSNTRKANIQLQECTAFIKMVKDKKPKDVTAMDRHCVRTCELLQRAESQYLLPIWRELVGEKTLIEYDMDFVVNLKRDVFDVLFEAQQFEHLGFTLPAVLRTAIMKKDLLFKDYERMTEVVDRYRSIINNLSMSEVIFLRGHIYDTELFIQMGVGRYTWTSFNIGKFCDQINSQLRKLTSIVSQINFIRLDLRSRIDMIKSFNLFNLDDELKVEDTSRSSGESYLQDRKNPSQRFKSVTGETITMFSVEKDVPADEKAEQACGSGIYPCQGYFELLEASRNRKAAQMKKLYDSLGPVLVKLESLVLGTFSGRSDRMKTYYEYWEGETFKCIVDMTYQNLKCYINRLLSNKPMFEVNAVLLMSEIVLEPSVQELQNTIVTATKDYISRLRIFTRWMTGTCIACPLVEMGKQFKYNYTYYEDVIQIRSIVDLVINIHDLASRVANEARGFVSQFRKYFNLWAFEKSFICQKFLEKQVTLIEIDEKFTFYSSIVETLANTRKFQDIKCVRINLEPLLASITQHAQDWCTTLGEELLRHVNDNMRAMRNEVKTLSLNLNKTTRELEDFKLVMTTIGTVQSSTLTNEQKIHEMQETFTILSEHKIMFPYEDMLMAHHLEKRWKRLFLSALYRYEKLQPIKQKFADMTSVEIDEFCDDLAEFIKDYDENGPGSVGAELERGVRLMDPYGQKIAERESRREELANAERLFDMAMVDYHEFARVQTEFEGLQQLYKLYKAQKYAREGWGKTLWADLDPNVLTEGVESYLKEFRKFTKAVRTLPVGVQLEIHMKQFKGTVPLMVSLKHEALRERHWLQLMEKTGQYFDMSPARFTLENMFAMQLHKYQEIAEQILTNAIKELQIERGVQAVIETWASMAFKTFKHFKGSDDRGWVLGPVDEIMQILEDNAMNLQSMGASQFIGPFLETVNKWERTLALISEIIDEWLVVQRKWLYLEGIFIGGDIRTQLPEEARKFDDIDKSYRRIMVDCAKNPLVVPFCTVPGRLVEIQGLGIGLENCQKSLNEYLDSKRRIFPRFYFISTDELLSILGSSEPSAVQNHIIKMYDNIKSLRLVKEGSQTIVTGMISSEGEVMEFRHSARAAGRVEYWMNDVLDEMRRSNRFINKTAIYDFGTDLQISRPDWLMNYQGMVGLAASQVWWTAEVEEAFDQAQNHGNMRAMKDFLGKNNYQIEELVLKVRSNLSRNDRLKFKAQCTVDVHARDIIDNFVRDNVLDASEFSWESQLRFYWIKFYDNLHVLQCSGSFDFGYEYMGLNGRLVITPLTDRIYLTITQALLMNLGGAPAGPAGTGKTETVKDLAKAMGLLCVVTNCGEGMDYRAVGTILSGLVQCGAWGCFDEFNRIDISVLSVISTQLQTIRNGLIRKLDRFVFEGVEIHLDPKCGVFVTMNPGYAGRTELPESVKALFRPVTCIKPDLELICLISLFSDGFLTAKVLAKKMTVLYSLAQAQLSKQCHYDWGLRSLNSVLRMAGVMKRQSEDLPEAVVLMRVLRDMNFPKFVFEDVPLFLGLIKDLFPGIDCPRIGYPDFNAAVRHVLVNDGYILLPDQEDKVVQMYETMMTRHSTMLVGPTGGGKTVVINALVKAQTHMGLPTKCLVLNPKACSVIELYGFLDMETRDWIDGLFSNIFREMNKPIEREERRYACFDGDVDALWIENMNSVMDDNKLLTLANGERIRLENYCALLFEVGNLNYASPATVSRAGMVYVDPKNLRYSPFWQRWVLTRPEPQRELLNDFFEKIITQSIAFILEGLDGTTQGNPLKLVIMQTDLNMVTQFCNLYDALLPNYVMDSKNYDEPVQQNYNTDSLECCFLQAVYGSMGACLVEKHQPVFDEYMKRISGFPLVQDTPENPASGGQFPQSKPTLYDYFWDVKDNVWKAWEWVVQPYTHDPQVKFSEILVPTVDNTRTNRTLSLMSEIKRPVLLVGEAGTSKTATIMQYLRNLNPSVNVILNINFSSRTSSLDVQHTLEAAVEKRTKDTYGPPMGKRIACFIDDMNMPQVDDYGTQQPIALLKLFFERGGMYDRDKDLNWKKFKDLTFYAAMGTAGGGRNEVDPRFISMFSTYNIIFPNDESLIQIYSSIFKGHMVFVKFQPEYMLIADMIVHMTLKLFKMVIVDLPPTPSKFHYIFNLKDLSRIFAGMLLIEPTCFKGLRDLIRVWRNEYTRIICDRLITDNDIANVRRNLAVEVAERFPPTFEEEHGFIDAAAAEAEAQARLLYEPSKADIDGGEEEGEEEEEGEEAPQVILSLKDYVLRDPLLFGDFRNFTNESEPRLYEDLLDYNSVYFLFTEILEEYCERKQKMTLVLFEDCLEHLTRVHRTLRMNRGHVLLIGVGGSGKKCITRLAAFAAECDVFEITISRGYNEAAFREDLKVLYTIAGVKRKKVVFLFTGAQVAEEGFLELINNILTVGQVPALFPDEDKDGIVNQVRKFAEEDGVSASKDAVWGYFLRTCAENLHVVLCMSPAGDALRNRCRNFPGLIGSTYIDWVFPWPRQALYAVAKLFLTEHRLIPASHREAIVEHVVHVHTSIQQYSKDYLAKLRRNNFVTPKHYLDYINTYRGLLEEKAKFITQQRSRLGEGIKKIEEASVQIDELRIIVTEQKKNVAVASEECEAMLVTIESSTQKANVKKAEASEKSVEVEIKGKQIAIEKDEAEEILAEAMPALEEARLALSQLEKAQITEIRSFATPPAAVQVVCECVAILKGYKEINWKSAKGMMSDVNFLKSLMEMDCEALTQKQITQCRQHMKTGNLEDMAKISVAGAGLLRFVRAVLGFFDVYKEVKPKKERLDFLVEEQEVQIKLLNHLNGEIQKLEEKLNELNENYATSMKQMRALTEMMQQAERRLIASDKLISGLTSELIRWSKEMASLGQQLIDSVGGCLISASFLAYTGAFTWEFRKAMVFDDWLEDIASLGIPIQLPFKIDGYLTTDVEISQWSNEGLPPDELSIQNGILTMRASRFPLCIDPQLQALQWIRKREFKNNLKVLSFSDSDFLKQLEMAIMYGTPVLFEDVDDYIDPVIDDILQKNIRIQGGRKFVMLGDKEVDWDPSFRVYLTTKFSNPKFDPAVYAKALVINYTVTQTGLEDQLLSVVVGTERPDLEAQRESLIAQTSENKQLLQQLEDSLLRELSTSTGNMLDNVELIETLENTKTKAGVVMEQLKLAADTAADIEVLRNGYRPAAKRGAVLFFALSDMATVNSMYQYALAAYLDVFVYSLRKAVPDASLNKRLNNIIKTLTENVYCYGCTGIFERHKLLFSFQIATKLAQRDGILLQSELDFFIKGSIALTKSERSNPCKWLSEKSWEDVLKLAFDFPDIFGTLPDHFGRYLTEWKEWFDLENPEEVPCPGDYNIKCNAFQKLMFLRCFRVDRIFRSINQYIVETMDEFYIMPPVVSFSAIYEQTSSTIPVCFVLSAGSDPTNDLIKLADTIVGMSNFCHISLGQGQEKAALRLLDGAIKQGMWLMLQNGHLLIRFVRELEKHLDRIENPHPDFRLWITTDPTPTFPIGILQKSLKVVTEPPNGLKLNLRSTYFKVRQERLESCSHVAFRPLVYVLAFFHAVVQERRKYDKLGWNIAYDFNDTDFDVCTEILRTYLTRCGTGKIPWNSLKYLIGEVMYGGRVIDDFDRRITNCYMNEYMGDFLFDEFKVFHFYEDDNVDYCLPEEETILKEDYIAHIDKLPLVNKPDVFGLHPNAEIGYYTMAARNIWNSLIELQPQTGEGTGGISRDDFIDSVAAGILKKLPPAFETWRIRKQIQMSLSPTGVVLLQELDRFNLLVVRIKKTLELLRKAIAGEIGMDNVLDNIANSLFNGLLPAAWSKLAPATCKQLASWLEHLRLRAVQYKYWTLSGEPLVMWLSGLHIPQSYLTALVQIACRRNAWPLDRSTLFTYVTKFADPDDVEERPVTGCLVHGLYIEGGRFDLATNQLARSHPKVLVEELAILAVEPIEAHRLKLQNTYLAPVYTTSLRRNAMGVGLVFEANLATSEDLSHWILQGVCLTLNTDT