wanglab/gogpt-training-data huggingface dataset:
Protein: DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3) (P24279)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Once loaded onto DNA, double hexamers can slide on dsDNA in the absence of ATPase activity. Necessary for cell growth.
Subcellular location: Nucleus.
Interaction partners:
- Minichromosome maintenance protein 5
- Topoisomerase 1-associated factor 1
- DNA replication licensing factor MCM2
- DNA polymerase epsilon subunit B
- DNA replication complex GINS protein PSF3
- Minichromosome maintenance protein 10
- DNA replication complex GINS protein PSF1
- DNA replication complex GINS protein SLD5
- Origin recognition complex subunit 2
- DNA replication complex GINS protein PSF2
Sequence:
MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSGSPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQLGLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTISTGRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNNLMVADDKVWRV
Protein: Turgencin-B (C0HLN6)
Organism: Synoicum turgens (Colonial ascidian)
Function: Has antimicrobial activity against Gram-positive bacteria (C.glutamicum ATCC 13032 (MIC=1.6 uM) and B.subtilis ATCC 23857 (MIC=1.6 uM)) and Gram-negative bacteria (E.coli ATCC 25922 (MIC=12.5 uM) and P.aeruginosa ATCC 27853 (MIC=25.0 uM)). Displays very low activity against the Gram-positive bacteria S.aureus ATCC 9144 (MIC>100 uM).
Subcellular location: Secreted {ECO:0000269|PubMed:31940927}.
Interaction partners:
Sequence:
GIKEMLCNMACAQTVCKKSGGPLCDTCQAACKALG
Protein: Protein ULTRAPETALA 1 (Q8GZA8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription factor that acts as a key negative regulator of cell accumulation in shoot and floral meristems. Negatively regulates the size of the WUSCHEL (WUS)-expressing organizing center in inflorescence meristems. May act by down-regulating expression of WUS. Acts as an antirepressor that counteracts EMF1 action through modulation of trimethylated 'Lys-4' on histone H3 (H3K4me3) marks on target gene loci (including genes involved in salt stress response and flower development). Collaboratively with RBL and CYP40/SQN, influences floral meristem (FM) determinacy in an AGAMOUS and SUPERMAN-dependent manner, thus contributing to the floral developmental homeostasis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15673576}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00185, ECO:0000269|PubMed:15673576}.
Interaction partners:
- Transcription factor HHO5
- Protein REBELOTE
- Transcription repressor KAN1
- Protein EMBRYONIC FLOWER 1
- Peptidyl-prolyl cis-trans isomerase CYP40
- Protein WUSCHEL
- Histone-lysine N-methyltransferase CLF
- Zinc finger protein KNUCKLES
- Chromo domain-containing protein LHP1
- Floral homeotic protein APETALA 3
Sequence:
MANNEGEMQCGSMLFKQEELQEMSGVNVGGDYVEVMCGCTSHRYGDAVARLRVFPTGDLEITCECTPGCDEDKLTPAAFEKHSGRETARKWKNNVWVIIGGEKVPLSKTVLLKYYNESSKKCSRSNRSQGAKVCHRDEFVGCNDCGKERRFRLRSRDECRLHHNAMGDPNWKCSDFPYDKITCEEEEERGSRKVYRGCTRSPSCKGCTSCVCFGCELCRFSECTCQTCVDFTSNVKA
Protein: Beta-mannosyltransferase 5 (EC 2.4.1.-) (WRY family protein 6) (Q5ALW2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Beta-mannosyltransferase involved in cell wall biosynthesis. Required for beta-1,2-mannose transfer on phospholipomannan.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MVQKQYRFAPKSIFTFVFLCFVAIVVIISTSSLVQVEESLDPIEVSDEIKKHDRKVVIFPSNFQSANNKLADFLTEAFGQRLNKGDIVYKNRDTYELPQTVYTWNTIDLFQSIGEKDNLKCEKIPLNFEISKIYNKNADLYKILRDFKNENSFYYKEVSVFFPDLGKQLRERTIEKHWFQLIGSSVWLEQYGVHLMISRVIYTKTGNKVQPVISLSYVQAFDRNWTELKNVTLVVPDSGKAKFKTVSYPSFIPIPVYHNVNQQRGKFYGVEDPRIMLVKNKEGYEEPLIVYNSFNRSPPNANYLEEIKNLVKLDTYRSIFMAWIWRTQLGKSNVGSSLPDLATTDDHKYVKVKELSLPNKKRPKTEKNWTPFVIYEDQKKQGYDSHLYFIYSFQDLSILKCSLWDAGNCIWEYRMNNKKTKISELRGGTELMNVNQLLDKYNFAGLETVKDQFKGKEVWISFARAALSKCGCGSKMYRPNFTVLVKQGGRFQLSFVSSYMDFGVPILPWAKGKGLCNGKNLLIPNGISNWVLAKDEGGGFQDYMTLSLSRSDSTVDIIHMKGILKSILSEYLLQTNRDVLNNNAIHCALLESESYCKSYAENYRAHLKRWQN
Protein: Probable feruloyl esterase B-1 (EC 3.1.1.73) (Ferulic acid esterase B-1) (FAEB-1) (Q2UP89)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MLVMQLLLPFLASTAAAAAAIDSTSSSNGSDHHGSSFQAECESFKAKINVTNANVHSVTYVPAGVNISMADNPSICGGDEDPITSTFAFCRIALNVTTSSKSQIFMEAWLPSNYSGRFLSTGNGGLGGCVKYDDMAYAAGYGFATVGTNNGHFGNNGVSFYQNTEVVEDFAYRALHTGVVVGKELTKNFYPQGYNKSYYLGCSTGGRQGWKSVQTFPDDFDGVVAGAPAFNFINLTSWGARFLTLTGDSSAETFVTETQWTAVHNEIIRQCDSLDGAKDGIIEDPDLCQPIIEALLCNATQSSTSGTCLTGAQVKTVNGVFSATYGLNGSFLYPRMQPGSELAAYSSYYSGTPFAYAEDWYRYVVFNNTNWDVATWTVQDAAIANAQDPYQISTWNGDLSPFQKKGGKVLHYHGMEDAIISSESSKVYYKHVADTMNLSPSELDSFYRFFPISGMAHCANADGPSAIGQGTGTFAGNNPQDNVLLAMVQWVEEGVAPDFVRGAKLNGSTVEYRRKHCKYPKRNRYVGPGSYTDENAWECV
Protein: Carbamoyltransferase HypF (EC 6.2.-.-) (Q8X849)
Organism: Escherichia coli O157:H7
Interaction partners:
Sequence:
MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGDGVEVRLLEDPETFLVQLHQHCPPLARIDSVEREPFIWSQLPTEFTIRQSAGGAMNTQIVPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPECGPYLEWVSHGEHAEQEAALQAAIAQLKMGNIVAIKGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIVLVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISNEQALEDLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVPPVLCLGADLKNTFCLVRGEQVVLSQHLGDLSDDGIQTQWREALRLMQNIYNFTPQYVVHDAHPGYVSCQWASEMNLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYPETASVQQQNWXVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEALAASCDGVTHPVTMPRVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMREQATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAARWLAGEVQNG
Protein: Uncharacterized protein C7D4.09c (O14264)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Dolichol kinase sec59
- Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Protein phosphatase methylesterase 1
Sequence:
MQLLNNWYSLLLTEVAAYFTSTTLFVSILKNAPSLSWLMKYGGHDNFGLKPPLIATKLEVPKRWFWHFYAFISLLNPLFTFFILNTNFPIPIFKNIKEDLMYSKKLQVLLLIYEIHTLRRLYENLRFRKSGSKMLAGHYLLGYLFYTHTFLALLLCGRRSYENTMSSMQFVGLGIYAIGSIWQNASHEHLIAQKNHSQYLVLKKGCFKWITGPHYLGEIIVYTGIALIAQHWLIWLVLGWVLCNMVAISSSYACTVKNKEQSLDFRWTLIPFLY
Protein: RNA-editing complex protein MP81 (Q586L9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nucleoside diphosphate kinase-like domain-containing protein
Sequence:
MRRLTRRSGRLSGKGNGGSCLQMSPTHVGAVVTWALNRLMPLHTRTIPLRCSLPTPESGTTEPRELCFYETFELTEEDVHYLLLHEAHVKHGVLLNVPPQLAPNGTPPEVPEVIMPAAQLERMGGMKLAYEPTHLPPPLHTTGARQLVLDESFYTTPTKEKKATTTAVSHVSESTAASGGRGGASATAAGTALPPRLPPDPTMKFHCSACGKAFRLKFSADHHVKLNHGSDPKAAVVDGPGEGELLGGAVTITTAKVAKHSSSAASGTASRAGDSATLDVKQQPDPQKELSAPGISAVKIPYSKAVLSLPDDELVDELLIDVWDAVAAQRDDVPKSNSANIFLPFASVVTGTADRRKEMEAVARPTARATPEGAAPGIKRPGAMAGGAVAVGKGRSGGQILPIRELIKKYPNPFGDSPNAAVQDLENEPLNPFLPEEELAAQLQVACEEDTVVTPSACTTDVSTGSVIGKKGSLEKLKEKLRGTRPSMAASAAKRRFTCPICVEKQQTLQQQQSENVGSGFCTDIPSFRLLDALLDHVESVHGEELTEDQLRELYAKQRQSTLYPQKSSTGDGAGSRETPDDSEKKEGSVGNTNMDELKSLPEEVRRVVPPAPVEQDALAVHIRAGSNALMIGRIADVQHGFLGAMTVTQYVLEVDGDERINSKGVTTPASACTPDPASTKAVEAKGEEGEVVEPEKEFIVIRCMGDNFPASLLKDQVKLGSRVLVQGTLRMNRHVDDVSKRLHAYPFIQVVPPLGYVKVVG
Protein: Ribosomal RNA small subunit methyltransferase I (EC 2.1.1.198) (16S rRNA 2'-O-ribose C1402 methyltransferase) (rRNA (cytidine-2'-O-)-methyltransferase RsmI) (P67087)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. In vitro, active on the assembled 30S subunit, but not naked 16S rRNA or 70S ribosomes.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Ribosomal RNA small subunit methyltransferase H
- Ribosomal RNA small subunit methyltransferase F
- Ribosomal RNA small subunit methyltransferase E
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- Ribosomal RNA small subunit methyltransferase G
- tRNA1
- Ribosomal RNA large subunit methyltransferase H-methyltransferase)
- Cell division protein FtsZ
Sequence:
MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNALYKYALEQQG
Protein: TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 68 kDa) (TAFI68) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B) (P97358)
Organism: Mus musculus (Mouse)
Function: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q53T94}.
Interaction partners:
- TATA box-binding protein-associated factor RNA polymerase I subunit C
- TATA box-binding protein-associated factor RNA polymerase I subunit A
- TATA box-binding protein-associated factor RNA polymerase I subunit D
- TATA-box-binding protein
- RNA polymerase I-specific transcription initiation factor RRN3
- Nucleolar transcription factor 1
- Transcription termination factor 1
- DNA-directed RNA polymerase I subunit RPA49
Sequence:
MDVEEVKAFRDRCSQCAAVSWGLTDEGKYYCTSCHNVTDRSEEVVSAADIPNTKINSINRGLRQRSKHEKGWDWYVCEGFQCILYHQAKALETLGVSPELKNEVLHNFWKRYLQKSKQAYCKNPVRTSGRKAKVLEDSVQSSDLGSDLELLSDTTCPLESEAEFQSDPQIPKPFPVTKGSPKSASVCSGSVDGVEYSERKEKGLVKMTVPRTLALCSLSLLWQRETITVSDLLRFVEEDHIPYINAFKLFPEEMKVYGRDKGIFAIESWPDYEDIYKNMIELAIFLDLPRFPDITEDCYLHPNTLCMKYLLEVNLPDEMHTLTCQVVKLTGIGEVDFLTFDPIAKTKRTVKYDVQAMAVIVVVLKLLFLLDDKLEWSYSDLAEAYNEQHREDTPQFDFRKWYQVMKKTFDEKRRKWEEARARYAWKTKRPLYRSHIDKSVAYKRRKMVENLQKQFSALVGSSPVVEKQAPSSFQFNWTEEGTDSPCFHGHSLQGLLIMKGQSMITKNSLYWLSTQKFCKSYCKHVTTYEESNFSLSYQFILNIFSFLLRIKTSALHEEVSLLEKKLFEKKYNESKKSSGSKKGRRH
Protein: Hyperkinetic, isoform L (M9PGS8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSMALCNLNGDGSAAQSTSQSQSQSPAATAAAAPLLPHSHSHTLQPESTPLLLGHEQSGSAAPEGSGGGDVTDGAVTSIEMPTVVADDAGVPPLPLPLPQSTPQPLLMALPANLNFITGPTTQQLMIGNGAMGVIPSTNDSNNNNNNNNNVDNTSDESNPVTIYRCRAPIASLDCMEEFSRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAHSETEIGKILQRAGWKRTAYVITTKVYWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCPMEVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMISTLALRXQSACPQGPLSLSGGGPCGADSPKHEDEAFIEEVDAAKDAAKQGFCLIQ
Protein: SLIT and NTRK-like protein 6 (Q8C110)
Organism: Mus musculus (Mouse)
Function: Regulator of neurite outgrowth required for normal hearing and vision.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MKLWTYLLYPSLLACLSLQSQSPMPSVRGSCDTLCNCEEKDGIMIINCEEKGINKLSQISVPPSRPFHLSLLNNGLTMLHTNDFSGLTNALSIHLGFNNIADIETGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITIIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCELLQLKNWLENMPPQSIIGDVICYSPPPFKGSVLSRLKKESFCPTPPVYEEHEDPSGSLLAITSSTSDSRLSSKNTSILKQPTKAPGLIPYLTKPSTQLPVPYCPIPCNCKVLSPSGLLIHCQERNIESLSDLQPPPHNPRKLILAGNIIHTLMKSDLTDYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLNKGMFLGLHSLEYLYLEYNAVKEILPGTFNPMPKLKVLYLNNNLLQVLPAHIFLGIPLTRVNLKTNQFTHLPVSNILDDLDFLIQIDLEDNPWDCSCDLVGLQQWIHKLGKGTMTDDILCTSPGHLDKKELKALNSDLLCPGLVNNPSMPTQTTYVIVTSPTVAADTASTLFSSLTDAVPLSVLILGLLIVFITIVFCAAGIVVFVLHRRRRYKKKKVEEQLRDNSPVHLQYSMYGHKTTHHTTERPSSSLYEQHMVSPMVHVYRSPSFGPKHLEEVEERNDKEGNDAKHLQRSLLERENHSPLTGSNMKYKTTDQSTDFISFQDASLLYRNILEKERELQQLGITEYLRKNLAQLQPEVEVNYPGAHEELKLMETLMYSRPRKVLVEQTKNEYFELKANLHAEPDYLEVLEQQT
Protein: Big bang, isoform J (PDZ domain-containing protein BBG-LP10) (Q15K24)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEVNAGGLAQLTDDKIADHDASATRADTRDEVTTNQTQEISSSSSSSVKSQKTTTTTRVTTTKTSSSSSSSSCSSTVIPDVAFKLQPYEERDDILSEPITTIHEERRVLSEQKTLSESRTRDALTGEEQLVTSANSKSSSARFKKISSNDNLLDLGDEQDMQEQPLTATITQESSLRERLECPQDNQSIDRGTLTLSERGKQLSEKEGLTTYTECETSEKESYLEGQQVLNGKGGFVSQDENSDQPTYEREVSETLTIVNDGEKQVTKKLEQNKEIAGKKGAKLLKKTDEERRLEQEAQKLIESYQKVKKEAEKLYKLELADDDQGFDLSAFEQAEEEDKPEVSEEIKEVKDSQPVKVDIQIEEEVKTPNQVIGEVKVEDVNKEIKETVQVSQQEIKKEVKVSHQETKETFKSEEKDESNELKIVKEEVKVTHQDLREQIQEIEAVKVVHKEVKVIKESAKVTTTTSHKQATKEVIISKEDHKNDSALPAVSTTKVEIISPPLEDDLGYVLHKHIIFPQEKVKTAPTPLPKPKPKPPVPTNKPKMPVNLTKPKSAPPPVPSKRSELSGSGGKPTPTQRRGSLETAQPPKPLERIIVGVEQRDEPEKPQPIINLASVDLPNVAPNSKQATVETTPVVEMPPDELQFESHQLPDDGEKEKDLHQESNDLLSGSSSSSVTTPITTPILVSATSSMDSVQSVIEVVNGMPIISNQQTDDDDIDEVAAYDDGMHLEAEGTKDVRPVQEVTTLTLDREHESDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEADPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA
Protein: Larval cuticle protein 4 (Larval cuticle protein IV) (P07189)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the larval cuticle.
Interaction partners:
- Larval cuticle protein 3
- FI01403p
- Larval cuticle protein 2
- Uncharacterized protein
Sequence:
MFKILLVCALVALVAANENPEVKELVNDVQADGFVSKLVLDNGSAASATGDVHGNIDGVFEWVSPEGEHVRVSYKADENGYQPQSDLLPTPPPIPEAILKAIAYIQAHPSKE
Protein: Forkhead box I2 (Forkhead box protein I2) (Q6NY62)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
Sequence:
MNTIDAQIHSNNNAAVNHLQQLPKSAHETSDMAVYCDNFSVYHQQSLPAAQRPAGYGLGDYATPNPYLWLNGPGVNSSSSYIHGNNSPSFIPPAYGSQRQYLSNSSGFAGPDLGWLSIASQEELLKLVRPPYSYSALIAMAIQNAHEKKLTLSQIYQYVADNFPFYKKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSDSSTGVSSNTKPEDDRQLAGIKPTDSPHLTGPASPDADAATDSHKGASPAGLASAPCFNNFFNSMSALGSSSTPTSRHGSLGLVNELSSRNISALSPYHASTGPEAGGAPELQDSVHVNRGMYYNSFTGGQSTQFNGHFYNSFSVNSLIYPRDGTEL
Protein: Proteasome subunit beta type-3-B (20S proteasome beta subunit C-2) (O81153)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular location: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
Interaction partners:
- Proteasome subunit beta type-4
- Proteasome subunit beta type-6
- Proteasome subunit alpha type-7-B
- Proteasome subunit alpha type-3
- Proteasome subunit beta type-2-B
- Proteasome subunit alpha type-5-A
- Proteasome subunit beta type-1
- Proteasome subunit alpha type-5-B
- Proteasome subunit alpha type-6-B
- Proteasome subunit alpha type-4-A
Sequence:
MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD
Protein: Small ribosomal subunit protein uS10 (40S ribosomal protein S20) (P60868)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P60866}.
Interaction partners:
- Small ribosomal subunit protein eS25
- Small ribosomal subunit protein eS28
- Small ribosomal subunit protein eS24
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS10
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein eS1
Sequence:
MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA
Protein: PWWP domain-containing DNA repair factor 3B (PWWP3B) (Mutated melanoma-associated antigen 1-like protein 1) (MUM1-like protein 1) (PWWP domain-containing protein MUM1L1) (Q5H9M0)
Organism: Homo sapiens (Human)
Interaction partners:
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- NADH-ubiquinone oxidoreductase chain 4
- NADH-ubiquinone oxidoreductase chain 3
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
Sequence:
MESEYVLCNWKDQLWPAKVLSRSETSSNSKRKKAFSLEVQILSLDEKIKLDSTETKILNKSQIEAIAASLGLQSEDSAPPTEETAYGRSLKVALGILNERTNLSQASTSDEEEITMLSQNVPQKQSDSPPHKKYRKDEGDLPGCLEERENSACLLASSESDDSLYDDKSQAPTMVDTIPSEVETKSLQNSSWCETFPSLSEDNDEKENKNKIDISAVMSVHSAVKEESACVKDEKFAPPLSPLSSDMLIMPKALKEESEDTCLETLAVPSECSAFSENIEDPGEGPSNPCLDTSQNQPSMESEMGAAACPGSCSRECEVSFSASNPVWDYSHLMSSERNFQRLDFEELEEEGQASDKSLLPSRINLSLLDDDEEDEELPRFILHYETHPFETGMIVWFKYQKYPFWPAVIKSIRRKERKASVLFVEANMNSEKKGIRVNFRRLKKFDCKEKQMLVDKAREDYSESIDWCISLICDYRVRIGCGSFTGSLLEYYAADISYPVRKETKQDTFRNKFPKLHNEDAREPMAVTSQTKKMSFQKILPDRMKAARDRANKNLVDFIVNAKGTENHLLAIVNGTKGSRWLKSFLNANRFTPCIETYFEDEDQLDEVVKYLQEVCNQIDQIMPTWIKDDKIKFILEVLLPEAIICSISAVDGLDYEAAEAKYLKGPCLGYRERELFDAKIIYEKRRKAPTNEAH
Protein: Capsid protein VP4 (A0A1W6I187)
Organism: Sulfolobus polyhedral virus 1 (SPV1)
Function: VP4 self-assembles to form, together with capsid protein VP10, an icosahedral caspid of 87 nm in diameter, with a T=43 symmetry and composed of 420 hexamers and 12 pentamers. VP4 proteins arrange into hexons, while VP10 proteins form the pentameric densities located at the 5-fold axes in the virion. The stoichiometry of VP4:VP10 is 42:1.
Subcellular location: Virion {ECO:0000269|PubMed:31636205}.
Interaction partners:
Sequence:
MSESVTQQVFNFAVTKSQPFGGYVYSTNLTASTSSAVTSTQLTPLNLSITLGQITLSGNSLVIPATQIWYLTDAYVSVPDYTNITNGAEADGVILIYKDGVKLMLTTPLISSMSISNPARTHLAQAVKYSPQSILTMYFNPTKPATASTSYPNTVYFTVVVVDFSYAQNPARAVVSANAVM
Protein: Malate dehydrogenase 2, peroxisomal (EC 1.1.1.37) (Microbody NAD-dependent malate dehydrogenase) (mbNAD-MDH) (Peroxisomal NAD-dependent malate dehydrogenase 2) (pxNAD-MDH2) (Peroxisomal malate dehydrogenase 2) (Peroxisomal MDH2) (Q9ZP05)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments (Probable). Peroxisomal NAD-dependent malate dehydrogenase involved in fatty acid beta-oxidation. Reoxidizes NADH from the beta-oxidation and provides NAD for the conversion of fatty acyl-CoA to acetyl-CoA. Does not participate directly in the glyoxylate cycle. Required for maintenance of photosynthetic rates under photorespiratory conditions, and carbon flow during photorespiration. Supplies NADH reductant to the peroxisomal hydroxypyruvate reductase (HPR), which reduces hydroxypyruvate into glycerate in the photorespiratory cycle.
Subcellular location: Peroxisome {ECO:0000269|PubMed:17376163}.
Interaction partners:
- Malate synthase
- Citrate synthase 3, peroxisomal
- Malate dehydrogenase, chloroplastic
- Citrate synthase 2, peroxisomal
- Citrate synthase 1, peroxisomal
- Fumarate hydratase 2
- Citrate synthase 5, mitochondrial
- Citrate synthase 4, mitochondrial
- Fumarate hydratase 1, mitochondrial
- NAD-dependent malic enzyme 2, mitochondrial
Sequence:
MEFRGDANQRIARISAHLTPQMEAKNSVIGRENCRAKGGNPGFKVAILGAAGGIGQSLSLLMKMNPLVSLLHLYDVVNAPGVTADVSHMDTGAVVRGFLGAKQLEDALTGMDLVIIPAGIPRKPGMTRDDLFKINAGIVKTLCEGVAKCCPNAIVNLISNPVNSTVPIAAEVFKKAGTYDPKKLLGVTTLDVARANTFVAEVLGLDPREVDVPVVGGHAGVTILPLLSQVKPPSSFTPQEIEYLTNRIQNGGTEVVEAKAGAGSATLSMAYAAAKFADACLRGLRGDANVVECSFVASQVTELAFFATKVRLGRTGAEEVYQLGPLNEYERIGLEKAKDELAGSIQKGVEFIRK
Protein: Stripe, isoform D (A0A0B4KGW2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- NGFI-A-binding protein homolog
Sequence:
MLLTMRRQNELIVGSQQHPSATSSASSSAGATSSPGLSGQNLNLVAGAGAATNSTSANSQDSLNTPTTPLLGLSRNPLQFAPPPAPPIAVPNPAASGPTFGYYQTVNAAPPIHHSPAATSEVSTAPQPPVELDEYVDILQVQQLLLDSSAAAAAAANNPPTTEQSVQQPQQNTVVQPHPHQQQQQQQQQQQPQQQQQQPQQILAKPRPRINLQKATEYAAQLAQAESSSPGSRRVLLDYPSPYLYGNPYHHHTPPGEDLVALWFGSNGTGGVAPGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTAAQSSGSPSTATYLSPAQFGGSHHGGASTSSNSLNSSSTASSSSTSSSLLHYTTASAAAAAAAAAAASANNSVLRARNQTATPTQGGSPGHVAVQPSATASSGRSSASHLSLLNTSGQHSPTSSAVEQVEAHKQLIEALPGDLNTPVTTSSDIPSFFGPTTVVEPPPITGSIESEDLSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEESSNNSCNMYPQHNNNNNNNNNTTSSSTTTTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNTSSSNSNCHHSHQQQQQQQQQQHMSSPQQQYQQHQILHQQQQLPNHHHHHHHHHHHHSQLQQLQQQQQQQQQQQQHQQQPLHQQQQLQHQQQQQHHQQHYQQHAIQHQQSQQQASKISYRGIFTTTGNAMNAAAAAAAAAAQQQHQQQQQHQQQLPSPQLGVLAGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPPSYAGASAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSTVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEKVRGEQQQQQQQQQQQQQQQQQQQLQQQQEQHHLSLQQHQQYQQHHLLHSADLAIVTSSASMXRLENSASSVDQAQTPTPTPAPAATQKVSLALALDLDESAFPFELTSDYGTLSPLTSPRQFNYVWVGQDSSQPFFYKDNVSVQEK