wanglab/gogpt-training-data huggingface dataset:
Protein: Testicular secretory protein Li 53 (A0A140VK53)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP
Protein: Corepressor (B3H7M7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein TOPLESS
- AFP homolog 2
- Auxin transporter protein 1
- Histone deacetylase 19
- Histone deacetylase 6
- Auxin-responsive protein IAA12
- Transcription factor MYC2
- Transcriptional corepressor LEUNIG
- Cyclic dof factor 1
- Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1
Sequence:
MDGSFHSPEWHAARLASLKTTHTLTWEEYKQKQKEEELKKQEVEADTDKLMREYRAQLDAERAMKLSKGRNYSSDISRKGRRESSQIESAEIPRGRKAKRESIRKGDHQTQAHLLNLQVVTKTNLGSQGQVLRGQRGRGNTSLEADTQNQSKDEADGPAPQSKFFGSLKS
Protein: Lipophorin receptor 2, isoform B (Q86B77)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MGPICRILGCSFLLLIAGLVPHHASRVVGLESTCSQEQFRCGNGKCIPRRWVCDRENDCADGSDESTSQCRGLCSSLMFMCKNGEQCIHREFMCDGDQDCRDGSDELECGNRTCRSDEFTCGNGRCIQNRFKCDDDDDCGDGSDEKNCGEKAKCGSNFFACKSGPCIPNQWVCDGDSDCRNGEDEMQNCTVSLLNFCQAGEFQCSDRITCLHKSWVCDGEADCPDGEDESQSNCLKVSCRPDQFQCNDQSCIAGHLTCNGKRDCADGSDEIMCDISATPRTCNATTEFDCGGGLCIPNAKVCNRRKDCPNGEDEPAGKCGINECSSKNGGCMHQCVNLEVGYRCECHDGYKLGADQHTCVDIDECETPGICSQVCVNEIGAFKCECEAGYMRLLKNHTRCKASEGHASLLLARRHDIRKIALDRPEMTSIVNSTKAATALDFVFRTGMIFWSDVATQSIYKAPIDEGNDRTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGASPRIERAGMDGTHRTAIITYDVKWPNGITLDLVQKRLYWVDGKLNTISSSNYDGSQRHQVLYSGEYLRHPFSITTFEDYVYWTDWDKQAVFKANKFNGMDVEPVTATHMLEHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLPAPRINERSPRISCACPTGLKLMPDGLMCVEDLETKTGNNRTDTSNQVHKSDAESENDYVEIALHVIASLAGTALVASVIYVVYRRCTRAVNSMNFENPVYHKTTEDHFSLEKNGTPHIYAAANDEEAVNPLFKSGTECV
Protein: Glutactin (P33438)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known. Binds calcium ions.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane.
Interaction partners:
- BM-40
- Spondin-1
- Viking, isoform A
- Peroxidasin
- Tiggrin
- RE36666p
- Papilin
Sequence:
MKPLLLVLALCGAQVHAHSVGLRPDYNDYSDEDTRRDWLPEPLKPVPWQSETRYAQPQEAVVQAPEVGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPIGYQGRVNATVQSPNCAQFPELDRLRLSESRGENVDDCLTLDIYAPEGANQLPVLVFVHGEMLFDGGSEEAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSSLALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAPPSEHRLWKQWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLNPLDRSLSRALVTMWVNFATTGVPNPSSGVWPQATSEYGPFLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPTTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQEFIREREQRRREQQLRDQQRYPQQEPREQQDERIRQQREQEERLRQQREQEERLRQQRELEERIRQQQEREQYEREQQEREQREREELERQQREREQQQPEQQPEYNPEPVNPWGYPVQEPQPDDNPEDGRLPYPSYEQYGPEGNENLPETDANRNFSEEDREQQQQEQLRREQQEQQEREYQLQLEREQQEREQQERGQQEPGPEEYPSYEEYSRALQEKNAERDRIYAEEQERERQQQETLLQENQQHPEQSLPEEQPTHPNYEAYDGDRSYAEEQEREQQRRDQVEQEREEQPDEDQGEEYERSPDEEEAAEQDVLKVEDFPSYEAYLEAATKLREEQEEQEKLEEERYRAQQEEEDRIQAERERNSRN
Protein: C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R) (O55197)
Organism: Rattus norvegicus (Rat)
Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Complement C3
- Complement C5
- Complement C1q subcomponent subunit A
- Complement C4
- Complement C4A.
- Complement C1q subcomponent subunit B
- Complement C1s subcomponent
- Integrin alpha-D
- High affinity immunoglobulin epsilon receptor subunit gamma
- Complement C1r subcomponent
Sequence:
MESFTADTNSTDLHSRPLFKPQDIASMVILSLTCLLGLPGNGLVLWVAGVKMKRTVNTVWFLHLTLADFLCCLSLPFSVAHLILRGHWPYGLFLCKLIPSVIILNMFASVFLLTAISLDRCLMVHKPIWCQNHRSVRTAFAVCGCVWVVTFVMCIPVFVYRDLLVVDDYSVCGYNFDSSRAYDYWDYMYNSHLPEINPPDNSTGHVDDRTAPSSSVPARDLWTATTALQSQTFHTSPEDPFSQDSASQQPHYGGKPPTVLIATIPGGFPVEDHKSNTLNTGAFLSAHTEPSLTASSSPLYAHDFPDDYFDQLMYGNHAWTPQVAITISRLVVGFLVPFFIMITCYSLIVFRMRKTNLTKSRNKTLRVAVAVVTVFFVCWIPYHIVGILLVITDQESALREVVLPWDHMSIALASANSCFNPFLYALLGKDFRKKARQSVKGILEAAFSEELTHSTSCTQDKAPSKRNHMSTDV
Protein: Succinate dehydrogenase subunit 8A, mitochondrial (Q0DF13)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9SKE0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9SKE0}.
Interaction partners:
- Succinate dehydrogenase subunit 5
- Succinate dehydrogenase subunit 6
- Succinate dehydrogenase subunit 8B
- Succinate dehydrogenase subunit 3-2
- Succinate dehydrogenase iron-sulfur subunit 2, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit 1, mitochondrial
- Succinate dehydrogenase subunit 4
- Succinate dehydrogenase subunit 7
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase subunit 3-1
Sequence:
MIYRNWSLLSSTVVIWGGVATAGLAGIFLFGGKEKFQNYLCREGERLRQQDRAAMGKN
Protein: Leucine-rich repeat protein (LRRP) (Q57ZD4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- U2 small nuclear ribonucleoprotein B, putative
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D2
- Sm protein B
- Sm protein G
- PHD finger-like domain-containing protein 5A
- Sm protein F
- Small nuclear ribonucleoprotein SmD1
- Splicing factor 3A, putative
- Probable eukaryotic initiation factor 4A
Sequence:
MYTTANRSYPDLLRSKNKERMNRIASRAISFSRAAYKGSSRVETSGEASNSEDEESCELEKFPAFVDPTEQQDHCIDPIIALKIPRSEYRNTKELELCRKNITRLHTNVQYLENLDTLVLSNNRISEVSFLLPPKRTADGNSRAENDAAVDDGVETLWCRPRGCHLLRSLFLSHNMIWTIDGDIPRLRHLRVLLLAYNRLANLVAVSTQLKRLRDLRELDLRGNPLCDELGYRPYLIREQPQLELLDRRLVQMEERNTVVSQLVQKDRELGSMCELGNILASSAPLQRRSIDSSIQRRSLQLSPLQDGRTQGLPTVAHTDPRFFSVTIGKEPVLKTLAFFKTFTPARQRADDPKVVPRRAFRPSACELYLGKSMHRLGKQKALREMREARENEMKREEVVETHKRFHLVWAMSGKGMPLCAEKLGAMSKQQETSQNAGNVEQTNVSPRNALMRRRASVAKQQAPDTTGKWAVKQAAPAPVVSLDRIQLPNLPPQLPGDTDHSVMYDALLHREDKVEKRIWGKPSCLPNPHRLENMKNLLDKASNFLTASQKKGSVGSSAVAFDHSQLLCEIQQCKDCTIPEPWEGDETSTSIVVTRDRQEFLCNAMMVLLLPSELSAIESHLMAGMADSFPHPEHQRGKKTSRKEKRALGDAARLPAGSGALLQGIATASASQRTQIIMAATNVEFGLPDRNTTRRLMNMLDFDSGLKNISLQNLTDAFANAYLSRTVETLPKPTSEMDDKCTASVTESKRNHRSPSAGRSRSDRRSGRRVSPTRSESRHVGREAAAASATKQPVLTLNTALLDLMLYLPFVRCRLEYFKEECDAAVKELGDLGDALPKRFSKLQAASLYYERLQEAMRLSGMSEESALNNFVDIEGILRLNAQEVGSYFRSNTTPV
Protein: Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP) (P61978)
Organism: Homo sapiens (Human)
Function: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:1729596}. Nucleus, nucleoplasm {ECO:0000269|PubMed:16360036, ECO:0000269|PubMed:1729596, ECO:0000269|PubMed:18775702, ECO:0000269|PubMed:22721921}. Cell projection, podosome {ECO:0000269|PubMed:22721921}. Note=Recruited to p53/TP53-responsive promoters, in the presence of functional p53/TP53 (PubMed:16360036). In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear (PubMed:18775702).
Interaction partners:
- Polypyrimidine tract-binding protein 1
- Heterogeneous nuclear ribonucleoprotein A1
- Desumoylating isopeptidase 1
- Nucleolin
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein L
- Poly
- RNA-binding motif protein, X chromosome
- KH domain-containing, RNA-binding, signal transduction-associated protein 1
- Heterogeneous nuclear ribonucleoproteins A2/B1
Sequence:
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF
Protein: Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein) (E9PS76)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSQATKRKHVVKEVLGEHIVPSDQQQIVRVLRTPGNNLHEVETAQGQRFLVSMPSKYRKNIWIKRGDFLIVDPIEEGEKVKAEISFVLCKDHVRSLQKEGFWPEAFSEVAEKHN
Protein: Hepcidin-1 (P61516)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity (By similarity).
Subcellular location: Secreted.
Interaction partners:
Sequence:
MKLSNVFLAAVVILTCVCVFQITAVPFIQQVQDEHHVESEELQENQHLTEAEHRQTDPLVLFRTKRQSHLSLCRFCCKCCRNKGCGYCCKF
Protein: Coronin-1C (Coronin-3) (Q9WUM4)
Organism: Mus musculus (Mouse)
Function: Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1. Increases the presence of activated RAC1 at the leading edge of migrating cells. Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments. Required for normal cell proliferation, cell migration, and normal formation of lamellipodia. Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission. Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (By similarity). Required for normal distribution of mitochondria within cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19651142, ECO:0000269|PubMed:22364218, ECO:0000269|PubMed:25074804, ECO:0000269|PubMed:25925950}; Peripheral membrane protein {ECO:0000269|PubMed:19651142, ECO:0000269|PubMed:22364218, ECO:0000269|PubMed:25074804, ECO:0000269|PubMed:25925950}; Cytoplasmic side {ECO:0000269|PubMed:19651142, ECO:0000269|PubMed:22364218, ECO:0000269|PubMed:25074804, ECO:0000269|PubMed:25925950}. Cell projection, lamellipodium {ECO:0000269|PubMed:22364218, ECO:0000269|PubMed:27178841}. Cell projection, ruffle membrane {ECO:0000269|PubMed:25074804}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19651142, ECO:0000269|PubMed:22364218, ECO:0000269|PubMed:25074804, ECO:0000269|PubMed:27178841}. Cytoplasm, cell cortex {ECO:0000269|PubMed:19651142, ECO:0000269|PubMed:22364218}. Endosome membrane {ECO:0000250|UniProtKB:Q9ULV4}. Note=Colocalizes with the actin cytoskeleton in the cytosol, and especially in the cell cortex (PubMed:19651142, PubMed:22364218, PubMed:25074804, PubMed:27178841). Colocalizes with F-actin at the leading edge of lamellipodia (PubMed:22364218). Partially colocalizes with microtubules and vimentin intermediate filaments (PubMed:27178841). Localizes to endosome membrane tubules/buds (By similarity). {ECO:0000250|UniProtKB:Q9ULV4, ECO:0000269|PubMed:19651142, ECO:0000269|PubMed:22364218, ECO:0000269|PubMed:25074804, ECO:0000269|PubMed:27178841}.
Interaction partners:
- Catenin beta-1
- Cadherin-1
- Catenin alpha-1
- Flotillin-1
- Flotillin-2
- Catenin delta-1
- Plastin-3
- Coronin-1B
- E3 ubiquitin-protein ligase CBL
- Actin-related protein 2
Sequence:
MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPAANKKSELSCAPKKPTDTASVQNEAKLDEILKEIKSIKETICSQDERISKLEQQLAKMAA
Protein: Mu-type opioid receptor (F1NW54)
Organism: Gallus gallus (Chicken)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Endosome {ECO:0000256|ARBA:ARBA00004177}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}.
Interaction partners:
- Proenkephalin
- Uncharacterized protein.
- Prepronociceptin isoform X1 variant X1
Sequence:
MAVAYLLGNGSAPLLAGALEVPFGANASAAACRPAVPPCAAAPPGAWGNSTAGWNRSEPCGGANGSAGGGPCAPAGGGGPSVVTAIAIMALYSVVCVVGLFGNFLVMYVIIRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYVAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPAWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIICWTPIHIYVIIKALVNIPETTFQTVSWHFCIALGYINSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTRDHASTANTVDRTNHQLELQEAETTPLP
Protein: Retinoic acid receptor RXR-gamma-A (Nuclear receptor subfamily 2 group B member 3-A) (Retinoic acid receptor RXR-alpha) (Retinoid X receptor alpha) (Retinoid X receptor gamma-A) (Q90416)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-cis retinoic acid (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
Sequence:
MDNNDTYLHLSSSLQVAHGHLSSPPSQPPLSSMVSHHHPSIINGLGSPYSVITSSSLGSPSASMPTTSNMGYGALNSPQMNSLNSVSSSEDIKPPPGLAGLGSYPCGSPGSLSKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYTCRDNKDCQIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGRERSDNEVDSSSSFNEEMPVEKILDAELAVEPKTEAYMESSMSNSTNDPVTNICQAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSVTVKDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDAKGLSNPSEVEALREKVYASLEGYTKHNYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQIT
Protein: ADP-ribosylation factor 1 (EC 3.6.5.2) (P84080)
Organism: Bos taurus (Bovine)
Function: Small GTPase involved in protein trafficking between different compartments (By similarity). Modulates vesicle budding and uncoating within the Golgi complex (By similarity). In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles (By similarity). The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasticity of excitatory synapses and spine shrinkage during long-term depression (LTD) (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:8505331}; Lipid-anchor {ECO:0000269|PubMed:8505331}; Cytoplasmic side {ECO:0000305}. Synapse, synaptosome {ECO:0000250|UniProtKB:P84079}. Postsynaptic density {ECO:0000250|UniProtKB:P84079}. Note=In the GDP-bound form, associates transiently with the membranes via its myristoylated N-terminus where guanine nucleotide-exchange factor (GEF)-mediated nucleotide exchange occurs (PubMed:9109679). Following nucleotide exchange, the GTP-bound form undergoes a conformational change, leading to the exposure of a myristoylated N-terminal amphipathic helix that provides stable membrane anchorage (PubMed:9109679). {ECO:0000269|PubMed:9109679}.
Interaction partners:
- Cytohesin-2
- Cytohesin 3
- Cytohesin 4
- Cytohesin 1
- Coatomer subunit gamma-1
- Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
- Phospholipase D2
- Phospholipase
- Coatomer subunit zeta-1
- Phosphatidylinositol 4-kinase beta
Sequence:
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK
Protein: Nicotianamine synthase 2 (EC 2.5.1.43) (S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 2) (AtNAS2) (Q9FKT9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Synthesizes nicotianamine, a polyamine which serves as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.
Interaction partners:
- Ferric reduction oxidase 2
- Protein DETOXIFICATION 43
- Fe
- Putative cadmium/zinc-transporting ATPase HMA4
- Transcription factor ORG2
- Metal tolerance protein A2
- Solute carrier family 40 member 2
- Fe
- Basic leucine zipper 19
- Fe
Sequence:
MACENNLVVKQIMDLYNQISNLESLKPSKNVDTLFRQLVSTCLPTDTNIDVTEIHDEKVKDMRSHLIKLCGEAEGYLEQHFSAILGSFEDNPLNHLHIFPYYNNYLKLGKLEFDLLSQHTTHVPTKVAFIGSGPMPLTSIVLAKFHLPNTTFHNFDIDSHANTLASNLVSRDSDLSKRMIFHTTDVLNAKEGLDQYDVVFLAALVGMDKESKVKAIEHLEKHMAPGAVVMLRSAHGLRAFLYPIVDSCDLKGFEVLTIYHPSDDVVNSVVIARKLGGSNGARGSQIGRCVVMPCNCSKVHAILNNRGMEKNLIEEYSAIE
Protein: Transcription factor BHLH3 (Basic helix-loop-helix protein 3) (OsbHLH003) (Protein RAC IMMUNITY 1) (bHLH transcription factor 3) (Q10S44)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor involved in defense responses that functions downstream of RAC1 and upstream of PAL1 and WRKY19 genes.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:22437844}. Cytoplasm {ECO:0000269|PubMed:22437844}. Note=Localizes mainly in the nucleus. {ECO:0000269|PubMed:22437844}.
Interaction partners:
Sequence:
MELDEESFLDELMSLRRDGSAPWQAPPYPGGGGGGGGGGMMMSDLLFYGGDGGSAEARGGMDASPFQELASMAAPPPQHPHEEFNFDCLSEVCNPYRSCGAQLVPSEAASQTQTQLTPLRDAMVAEEETSGDKALLHGGGGSSSPTFMFGGGAGESSEMMAGIRGVGGGVHPRSKLHGTPSKNLMAERRRRKRLNDRLSMLRSIVPKISKMDRTSILGDTIDYVKELTERIKTLEEEIGVTPEELDLLNTMKDSSSGNNNEMLVRNSTKFDVENRGSGNTRIEICCPANPGVLLSTVSALEVLGLEIEQCVVSCFSDFGMQASCLQEDGKRQVVSTDEIKQTLFRSAGYGGRCL
Protein: Serine protease HTRA3 (EC 3.4.21.-) (High-temperature requirement factor A3) (Pregnancy-related serine protease) (P83110)
Organism: Homo sapiens (Human)
Function: Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.
Subcellular location: Secreted {ECO:0000269|PubMed:21321049}. Note=Secretion increased during decidualization of endometrial stromal cells.
Interaction partners:
Sequence:
MQARALLLAALAALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGGPLDSPCGESLECVRGLCRCRWSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQLQKGACPLGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVM
Protein: Prophage LambdaSa2, lysin, putative (Q8DXL3)
Organism: Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Interaction partners:
- Prophage LambdaSa2, holin, putative
- Phage protein
- Prophage LambdaSa2, PblB, putative
Sequence:
MEINTEIAIAWMSARQGKVSYSMDYRDGPNSYDCSSSVYYALRSAGASSAGWAVNTEYMHDWLIKNGYELIAENVDWNAVRGDIAIWGMRGHSSGAGGHVVMFIDPENIIHCNWANNGITVNNYNQTAAASGWMYCYVYRLKSGASTQGKSLDTLVKETLAGNYGNGEARKAVLGNQYEAVMSVINGKTTTNQKTVDQLVQEVIAGKHGNGEARKKSLGSQYDAVQKRVTELLKKQPSEPFKAQEVNKPTETKTSQTELTGQATATKEEGDLSFNGTILKKAVLDKILGNCKKHDILPSYALTILHYEGLWGTSAVGKADNNWGGMTWTGQGNRPSGVTVTQGSARPSNEGGHYMHYASVDDFLTDWFYLLRAGGSYKVSGAKTFSEAIKGMFKVGGAVYDYAASGFDSYIVGASSRLKAIEAENGSLDKFDKATDIGDGSKDKIDITIEGIEVTINGITYELTKKPV