wanglab/gogpt-training-data huggingface dataset:
Protein: Down syndrome cell adhesion molecule 1, isoform BB (Q0E9M3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVPQSYTVNVMDESILRGNSAILKCHIPSFVADFIVVDSWVEDEERVIYPQEDIAESDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGSVAPKVDVKDRITWLDKPMGQALSLLCPAQSYPMPVYRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPQVLPFSFGESAADVGDIASANCVVPKGDLPLEIRWSLNSAPIVNGENGFTLVRLNKRTSLLNIDSLNAFHRGVYKCIATNPAGTSEYVAELQVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: RE54143p (Q7YU57)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSRRTPPITTVATGYSVLIEAVSAYPLLYDSTCTGYQNTRHRFLIWSAISNEVHDKATKLMKCWLKLQTRYEWELIHRPRHIGTSELCRLMDFMEPHVQRMRGTVCKSSKYLQNGWHEPIENFHTVMALITTMRNMPELVQLTEDSLHNKVKPPRYDEFWQKVGMEVMCSHEHCEVTWLVLRAFYHELQAVRSSGYQLQDKWFFEGSMGLALTPVTSRSTARPALKRTANGAIPVAGEPPAKTPVPVRMPLAIVYPSTSKGSSTSMTNSASTATSIGPTFTNVRRSSGPVINNTSTAAAATNSVSSSVSPDQALPKFVIPKITSAISVGSGYMIPLKFVPNVRILPKPAATMGTGVSPIATTNQMAGPNAKPPEVRPQITQGPGLQVKLHTKPQMASRPQMAPVVPRTVIRTTNPTNPAQTQDRVSGGPMSTLGELLRPQNPSQIRSPAPQQTLPNFVPITTSNITAKSNLPTPTAAPMVRIHQPGLKSAWDGKSNSAPFSKPIRSLLTTSSPAAAPIVATAEPARAKIIPPKPKLPATTLVNPKKYQPIVPVAVLPTAATRMAKPATEPATELPVTTPPIATGQTTRVIRKTPLFPTSATQAASDSYATIQGTLASQAKAVGAAISAPVVRPAKLPTVAKATTASQSDIKATAAASATLGSQPENLPLGNITVCLHESDTTGNELQVWCGNQGTRFNLNMIRTTTLIREVMAVPQLHKEDPQLAAKCVEFWHFIAKKFHMPEEALRACWKFLAANMSVFPKIAPMSELMRPFKYSEKVWEKSNRLFGKFDEIALKYQWLNHKNVLPEVIRFFAKYEYLYCDLRRPRPGEDAQAPPQLTNQEKQEVWREARLKFPNLNHRDIWSMFKFAFRTYLDDLERGIDNPWPQNWWQALEQLRFLVNVRYHPLEPYYYIVHNRMSEEVKRCKMHEALTSSDHIDKTKFTPSKLLTGFSKEPKPWETEEAKRLLTGKLNSVRSTETLTQIAPAPALALAPDAQPIPVPDGVSVSKKTSESKPASNANVKSHKDKNISTAQKRPTPARSVTCNNLSPIEAFELCKKLRSQPNSFERASTLDKRAAWVRVSKELHATVTECRLGLSTLCARCAI
Protein: GDNF family receptor alpha 3 (Q6AXR3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
- Artemin
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Neurturin
- Persephin
- Glial cell line-derived neurotrophic factor
- GDNF family receptor alpha-1
Sequence:
MGLSRSPRPPPLVILLLVLSLWLPLGTGNSLPTENRLVNSCTQARKKCEANPACKAAYQHLDSCTPSLSSPLPSGESATSAACLEAAQQLRNSSLIDCRCHRRMKHQATCLDIYWTVHPVRSLGDYELDVSPYEDTVTSKPWKMNLSKLSMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACSGIRCQRHLCLAQLRSFFEKAAESHAQGLLLCPCAPEDAGCGERRRNTIAPSCALPSVAPNCLDLRSFCRADPLCRSRLMDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFISKVNTTVALGCTCRGSGNLQDECEQLEKSFSQNPCLMEAIAAKMRFHRQLFSQDWADSTFSVMQQQNSSPALRPQLRLPVLSFFILTLILLQTLW
Protein: Myosin, heavy chain 7B, cardiac muscle, beta a (R4GDZ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSRMLDMKEFGEAAPFLRKSDLELLAAQTVAFDGKKRAWIPDDKDAYIEVEIKQIDGDRVEVETKDGKCLTVKEDDIQQMNPPKFDLIEDMAMLTHLNEASVLFNLRRRYSSWMIYTYSGLFCVTVNPYKWLPVYTAPVVAAYKGKRRSEAPPHIYSIADNAYNDMLRNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALGEAAAKKGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPTGKLASADIDIYLLEKSRVIFQQPGERSYHIYYQIMSQKKPELLDMLLVSSNPYDYHFCSQGVTTVENMDDGQELMATDHAMDILGFTPEEKYGCYKIVGAIMHFGNMKFKQKQREEQAEADGTESADKASYLMGVSSADLIKGLLHPRVKVGNEYVVKGQNVEQVNYAVGALAKATYDRMFKWLVGRINRTLYTALPRQFFIGVLDIAGFEIFELNSFEQLCINFTNEKLQQFFNHHMFILEQEEYKREGIEWTFIDFGLDLQACIDLIEKPLGIMSILEEECMFPKATDNSFKAKLFDNHLGKSANFQKPRPDKKRKYEAHFELVHYAGVVPYNIIGWLDKNKDPLNETVVICFQKSSNKLLASLYEKYVSSDSASDPKTGGKEKRKKAASFQTVSQLHKENLNKLMTNLRSTQPHFVRCIIPNETKTPGIMDSFMVLHQLRCNGVLEGIRICRKGFPNRMLYAEFKQRYRILNPHAIPDDKFVDSRKAAEKLLASLDIDHNQYRFGHTKVFFKAGLLGQLEEMRDERLAKILTLLQAASRGKIMRMELNKMTQRKEALMIIQWNIRAFNIVKNWPWMKLFFKIKPLLRSAATEKELAALKEEFLKLKEALEKSEAKRKELEEKQVSLIQEKNDLSLQLQAEQDNLADAEDRCDLLIKTKIQLEAKVKEMTERLEDEEEMNATVLAKKRKLEDECAELKKDIDDLEITLAKVEKEKHATENKVKNLIEEMAALDETILKLTKEKKALQESHQQTLDDLQTEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERSKRKLEGDLKLSMESVMDLENDKQQLEEKLKKKDFEMNQISSKIEDDQVLIIQLQKKIKELQARIEELEEEMEAERSTRAKMEKHRSDSSKELEELSERLEEAGGATSAQIEMNKKREADFLKLRRDLEEAILHHEAMTAALRKKHADSVVELSEQIDSLQRVKQKLEKERSEAKMEADDLTSNLEQLAKGKATAEKTCRLYEDQMNESKAKVEELQRQLSDTNTQRARAQAESAELGRKLEEREALVSQLQRSKNTFSQNIEELKKQLEEESKSKNALTHALQSSRHDCDLLREQYDEEQEGKSELQRALSKANAEVAQWRTKYETDAIQKTEELEEAKKKLATRLQESEEQVEASNAKCSSLEKTKHRLQSEIEDLVLDLERSNAAATALDKKQRQFDKILAEWRHKYEECQSELESSQKESRNLSTELFKLKNSYEEALDHLESIKRESKNLQEEISDLNDQISQGGKTIHELEKIKKGLDLEKTEIQAALEEAEGTLEHEESKTLRIQLELNQIKADTDRKLAEKDEEIDNLRRNHQRALESMQATLDAEAKSRSEAIRVKKKMENDLNEMEVQLNHANWLATESQKMVRNLQTQIKDLQMELDETVHQNEELKEQSAVTERRNNLLTAEVEELRCQLEQNDRARKLAEFELLETTERVNLLHSQNTSMLNQKKKLENDLATLSSEVDDAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQLRLDEAEQIALKGGKKQIQKLESKVRDLESELESEQKKSNELQKGIRKYERRIKELTYQTEEDRKNIARLQELIDKLQAKVKTYKRQAEDAEEQANSNLTKYKKIQHELDDAEERADIAESQVNKLRTRSRDSGSKTTPKLAE
Protein: Coiled-coil domain-containing protein 43 (Q86WV7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEESLTEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR
Protein: Protein RETICULATA-RELATED 6, chloroplastic (Q8RWG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in leaf development.
Subcellular location: Plastid, chloroplast membrane {ECO:0000250|UniProtKB:Q9C9Z2}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- GTP-binding protein At2g22870
- Putative nucleobase-ascorbate transporter 9
- Ribonuclease III domain-containing protein RNC1, chloroplastic
Sequence:
MKLTTNDLFASQPLFHCPCSSSSRPRRRRFYGLHFPINLTSEKNNSLSIVALSDSDLPSRTAFSRRAFLLAPPLLVSAASLFLKPSVSLASEESSSATVTSPAESAAPPPPPATTTPSPPPPVNKEETITSRIYDATAIGEPMAMGKDKKKVWEKLLNARVVYLGEAEQVPTKDDKELELEIVRNLRKRCVESERQISVALEAFPLDLQDQLNQYMDKRMDGETLKSYVTHWPAQRWQEYEPLLSYCRDNSVRLIACGTPLKVLRTVQAEGIRGLSKSERKLYTPPAGSGFISGFSSFSRRSTFDMSLPTQIVPFGPSSYLSAQARVVEDHTMSQVILQAVADGGGTGLLLVVTGASHVEYGSRGTGLPARISRKFPKKNQVVVLLDPERQFLRREGETPVADFLWYSAARPCSRNCFDRAEIARVMNAAGRRRDALPPDIQNGLDLGLVSPEVLQNLFDLEQYPLISELTQRFQGFRERLLADPKFLNRLAIEEAISITTTLIAQYEKRKENFFEEIDYVITDTVRGSVVDFFTVWLPAPTLSFLSYADETTGPDSIDALRGLLGSIPDNAFQKSLAGREWNLNLRIASVIVGGLKLAGVGVVSSFAAVGASNALNIARKVIKPELVVAEKPKRSPLLKTAMVYGGFLGTSANLRYQIIAGLIEHRLSDELSSQPLLVNAISFVVRTLNSYFGTQQWIDLARSTGLQTQKSIPASKEISEALEEPTVECDTTTEEESIDKLNNQ
Protein: ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit Ku80) (Q4WI96)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Chromosome, telomere {ECO:0000250}.
Interaction partners:
- ATP-dependent DNA helicase II subunit 1
- DNA ligase 4
- 3'-5' exonuclease/helicase
- Double-strand break repair protein
- ATP dependent DNA ligase domain protein
- Orotidine 5'-phosphate decarboxylase
- Serine/threonine-protein kinase tel1
- Serine/threonine-protein kinase TOR
- Exosome complex exonuclease Rrp6, putative
- Telomerase reverse transcriptase
Sequence:
MAEKEATVYIVDVGKSMGEKRNGRSMTDLEWAMQYVWDCITATVATGRKTATIGVIGLKTDETSNELDDDPHFKHISVFTEIQQFLMPDIRRLGALVKPSETDKGDAISAIILAIQMIVTYCKKLKYKRKIVLVTNGQGWMSNEDLDQITKKIKEDNIDLVVLGTDFDDPEYGFKEEGKDPRKAENEALLRGLVEDCNGAFGTLEQAVSEMDIPRAKRVRTVATFKGFLQLGNPEEYDTALRIPVERYYRTYVAKPPSASSFVLRSDVGAEGEQGESSQLPKSPPEGGALTSVRNLRTYEVPDENAPGGKFDVEREELAKGYEYGRTAVHISETDENITTLETYAALELVGFIQTDKYDRYMHMSTTNIIIGQRGNDKASLALSSFIHALFELECYAVARLVVKENKPPVMVLLAPSIEPDYECLLEVQLPFAEDVRTYRFPPLDKVITVSGKVVTEHRNLPNKDLLDAMSEYVDSMELVDTDETGNPVEGLPIDDSFSPVLHRIDSAIRYRAIHPDDPVLPPSKNLTKLSQPPQDLVEKSKAYLQKLMEAADVKKVPPKVKGRKRIRESEKPLSGLDVDALLHQEKRARISPTNAIPEFKQTLTQAETIETIKDAVKQMTSIIEDQIKNSLGDANYDRVIEEMGVMREELISFEEPALYNDFLRQLKDKLLKEELGGDRRELWWLLRRSQLGLINQRESDQSDVTEEQAKEVSLRCHLSSRGIY
Protein: Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) (Proteasome subunit beta-2) (beta-2) (Q99436)
Organism: Homo sapiens (Human)
Function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12181345, ECO:0000269|PubMed:18549262, ECO:0000269|PubMed:34711951}. Nucleus {ECO:0000269|PubMed:12181345, ECO:0000269|PubMed:18549262, ECO:0000269|PubMed:34711951}. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9. {ECO:0000269|PubMed:34711951}.
Interaction partners:
- Proteasome subunit beta type-5
- Proteasome subunit beta type-4
- 26S proteasome non-ATPase regulatory subunit 6
- Proteasome subunit alpha type-1
- Proteasome subunit beta type-6
- 26S proteasome regulatory subunit 6A
- 26S proteasome non-ATPase regulatory subunit 11
- Proteasome subunit alpha type-2
- 26S proteasome non-ATPase regulatory subunit 3
- Proteasome subunit alpha type-7
Sequence:
MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS
Protein: CHOp24, isoform A (CHOp24, isoform B) (GH04989p) (Q9W4K0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00037847}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00037847}. Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}.
Interaction partners:
- Transmembrane emp24 domain-containing protein bai
- LP01981p
- P24-related-1, isoform A
- Transmembrane emp24 domain-containing protein eca
- Protein transport protein SEC23
- Surfeit locus protein 4 homolog
- Secretory 22, isoform B
- Weary, isoform B
- Delta-like protein
- BET1 homolog
Sequence:
MESTLAKVLLLVGSLLILCRTSHAFIVSVDAHNEECFFENVEGGTKFGVTFEVIDGGFLDVDIKISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCFNNERSSMTPKLVMFSIDVGDAPQRAPGAPGEEEVGHTKLEDMIRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWSTFEALVLVLMTVGQVYYLKRFFEVKRVV
Protein: Elongation factor 1-alpha 2 (EF-1-alpha 2) (P86939)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- GST N-terminal domain-containing protein
- Eukaryotic peptide chain release factor subunit 1
- Activated protein kinase C receptor homolog
- Small ribosomal subunit protein uS5
- 60S ribosomal protein L4
- 60S ribosomal protein L5, putative
- 60S acidic ribosomal protein P0
- Elongation factor 2
- Eukaryotic translation initiation factor 5A
- Translation elongation factor 1-beta, putative
Sequence:
MGKEKVHMNLVVVGHVDAGKSTATGHLIYKCGGIDKRTIEKFEKEAADIGKASFKYAWVLDKLKAERERGITIDIALWKFESPKSVFTIIDAPGHRDFIKNMITGTSQADAAILIIASAQGEFEAGISKDGQTREHALLAFTLGVKQMVVCCNKMDDKTVNYGQERYDEIVKEVSAYIKKVGYNVEKVRFVPISGWQGDNMIEKSEKMPWYKGPTLLEALDMLEPPVRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVMKPGDVVTFAPANVTTEVKSIEMHHEQLAEATPGDNVGFNVKNVSVKDIRRGNVCGNTKNDPPKEAADFTAQVIILNHPGQIGNGYAPVLDCHTSHIACKFAEIESKIDRRSGKELEKAPKSIKSGDAAIVRMVPQKPMCVEVFNDYAPLGRFAVRDMRQTVAVGIIKAVTKKDGSGGKVTKAAVKASKK
Protein: Polyadenylate-binding protein 1 (F4KBV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MPVHDEQEHEVYGGEIPEEEEGEMDTEEYEEHGGEEGAAAGDEELEPGSSSRDLEDMKKRIKEIEEEAGALREMQAKAEKDMGASQGLKLVLLIMILLWVYILESFSESMNLSRNLLEFEYEKEIINSGVSAAEKEEVDSRSIYVGNVDYACTPEEVQQHFQSCGTVNRVTILTDKFGQPKGFAYVEFVEVEAVQNSLILNESELHGRQIKVSAKRTNVPGMRQFRGRGRPFRPMRGFMPGVPFYPPYAYGRVPRFRRPMRYRPY
Protein: AMP nucleosidase (EC 3.2.2.4) (P0AE12)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
Interaction partners:
- Purine nucleoside phosphorylase DeoD-type
- Adenine phosphoribosyltransferase
- Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase
- Adenine deaminase
- Pyrimidine 5'-nucleotidase YjjG
- GMP/IMP nucleotidase YrfG
- Pyrimidine-specific ribonucleoside hydrolase RihB
- Pyrimidine/purine nucleoside phosphorylase
- Adenylate kinase
- Nucleoside triphosphate pyrophosphohydrolase
Sequence:
MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDENARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLTLLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETADGIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGCSQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLVNIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAVLPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASALRFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAISEHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR
Protein: Cleavage and polyadenylation specificity factor 30 kDa subunit (Q86G58)
Organism: Trypanosoma brucei rhodesiense
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFTDNAAHTSLAFEDTLPVEAPATAKRSEICQPFQHGKCRNGAACPERHVLSQFKSMRLEVCKHWLRGACVNGENCVYLHEYDDRYVPACAFYQRLGECSNPECPFQHVVQVERQPECAAYRRGFCPLGPKCRLRHVFRPPCVFYLTGFCPLGPKCALGHPVQQLYNRNDVSERLRQRMLIERADDPSFNKNATCYRCFDPGHLSPNCPGMQSGLLRRLLMALQEPGEQLYFQSDGRAARKCCFFCGEEGHEVRDCPKKQKPQQWGGHRRGDATGRQ
Protein: NADH-quinone oxidoreductase subunit N (EC 7.1.1.-) (NADH dehydrogenase I subunit N) (NDH-1 subunit N) (P9WIW9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular location: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00445}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00445}.
Interaction partners:
- NADH-quinone oxidoreductase subunit C
- NADH-quinone oxidoreductase subunit G
- NADH-quinone oxidoreductase subunit J
- NADH-quinone oxidoreductase subunit H
- NADH-quinone oxidoreductase subunit I
- NADH-quinone oxidoreductase subunit B
- NADH-quinone oxidoreductase subunit K
- NADH-quinone oxidoreductase subunit D
- NADH-quinone oxidoreductase subunit F
- NADH-quinone oxidoreductase subunit M
Sequence:
MILPAPHVEYFLLAPMLIVFSVAVAGVLAEAFLPRRWRYGAQVTLALGGSAVALIAVIVVARSIHGSGHAAVLGAIAVDRATLFLQGTVLLVTIMAVVFMAERSARVSPQRQNTLAVARLPGLDSFTPQASAVPGSDAERQAERAGATQTELFPLAMLSVGGMMVFPASNDLLTMFVALEVLSLPLYLMCGLARNRRLLSQEAAMKYFLLGAFSSAFFLYGVALLYGATGTLTLPGIRDALAARTDDSMALAGVALLAVGLLFKVGAVPFHSWIPDVYQGAPTPITGFMAAATKVAAFGALLRVVYVALPPLHDQWRPVLWAIAILTMTVGTVTAVNQTNVKRMLAYSSVAHVGFILTGVIADNPAGLSATLFYLVAYSFSTMGAFAIVGLVRGADGSAGSEDADLSHWAGLGQRSPIVGVMLSMFLLAFAGIPLTSGFVSKFAVFRAAASAGAVPLVIVGVISSGVAAYFYVRVIVSMFFTEESGDTPHVAAPGVLSKAAIAVCTVVTVVLGIAPQPVLDLADQAAQLLR
Protein: KIAA1218 protein (A4D0Q3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKHRNPSHRASGPSPLFRTCLTNLLSLSNIGAAWVSTLESVAPRYPLNLAAQTPGPGGPEPGGMAADGGVEDIRKKRNGQDSFFFNKHLTLHQEPPTQYSLSARKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVRDLLAPPSPALGGRGSWAAPLLSRAAPTGNTSLIPVLVFPEGSFHPLL
Protein: Fumarate hydratase class II (Fumarase C) (EC 4.2.1.2) (Aerobic fumarase) (Iron-independent fumarase) (P39461)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000305}.
Interaction partners:
- succinate dehydrogenase
- Malate dehydrogenase
- Succinate dehydrogenase subunit B
- NAD-dependent malic enzyme
- Citrate synthase
- Succinate--CoA ligase subunit alpha
- Aconitate hydratase
- Succinate dehydrogenase subunit C
- Succinate dehydrogenase subunit D
- Succinyl-CoA synthetase, beta subunit
Sequence:
MKYTDTAPKLFMNTGTKFPRRIIWSMGVLKKSCAKVNADLGLLDKKIADSIIKASDDLIDGKLDDKIVLDVFQTGSGTGLNMNVNEVIAEVASSYSNLKVHPNDHVNFGQSSNDTVPTAIRIAAVAEVTNRLLPALQQIISSLNKKAEEYKDVIKAGRTHLRDALPVTLGQELSAYADAFQHEHEQVMNILEYVKELPIGGTATGTGLNSHPEFQERVINEINRITGLGFKPANRFRAMRLLTDLLLLSGALRNIAVDLYRLGQDIRLMFSGPLTGLNEIDLPTQEEIAGSSIMPGKTNPVTVEATLLISAQVVGLDHANQFASMLGEFELSMGIPLVGYNIVTQVNFISEALEKMSRLVIDGMVANVEKMKRYAESSPSLITIVSPVIGYDKATEIGKKLNKGMSIREALRELGYSDNEINKILDLSKLVKPGFTAK
Protein: Heat shock transcription factor (HSTF) (Heat shock factor protein) (HSF) (J9VHZ9)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription. Promotes thermotolerance by transiently regulating a subset of genes. Induces expression of STI, SSA1, SSA2, HSP78 and KAR2 during the heat response.
Subcellular location: Nucleus {ECO:0000305|PubMed:27866167}.
Interaction partners:
Sequence:
MTTNLYAIAGPSKPTTPTSTPSPRSEPPSPLKSLTSLPTNPLNPQGTSTSNALTNQSSSTGIGISKPGLSVDENGEVMKVPAFLNKLYTMVSDPEVDDLIYWGENGDSFFVPNAELFGRELLPRWFKHSNFSSFVRQLNMYGFHKVPHLQSGALKNETPIELWEFANPYFKRGQPQLLTKVTRKNNRLSNSGVGSSSSLGGSGAGGGMNTRSASAAAASGSGSGQIQQAISQGHEAGNHSTSGKYLITDGTTPGSAPPSHTSAGPLIAPQTLDLSAINSGIAAIRQTQASIATDLRKLQASNEALWRQAYETQEKQRKHEETIDLIVSFLERLFGTEGEGLKGLKEAMRRGVGVRRDRDGREGRDSRDARFADDDDGGQKKRRRVGLDRMIEGGSGDGTGEHGEIESPSSDDRLVEIGSNSEYSIPSVKRTSSSSHPLSLGQLGSSRFTALPSEDPSPSGSGLGSTPYEGLRTTQASAHGAGADVNVTDPTLGMNHLSPLSDTDPLLPSSSNALAPYTSHPSFPSSNPNPSSAWAFNPSQPLLSPTSAVAAAHAYNLDPSLLQTTIGSLLQSPAVAQMFLKSLSASAQGQALTSHSHPHNPSLLNPNPNGNASTSASASAHDMNTEGLGTGSGTKDLDPTLALFSPLPSHSSLASQSNDLLKSYNDALTVGEGVDNLQESIDSLVRSMGLDLPNGGSSSVGVDVGDGSGVGTGTGEGDGEFNVDEFLQGLAKEGEGEEGEREVGGDGDASSSGAGAENGRKEDVIAQSGLK
Protein: Myosin binding subunit, isoform G (A8JNT5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKKPTVTIATSTAATAINSPSTTVQTPPIRRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSNDKTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFANAQLDAYKSDNHRLKEENAALIRVISKLSK
Protein: Disease resistance protein-like (Leucine-rich repeat (LRR) family protein) (Q9FHL8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- At1g66850
- Peroxidase 66
- Non-specific lipid-transfer protein 10
Sequence:
MQNLKWVLMNLLFVSALVRNFVLSSSQQVICSSQDRATLLGFKSSIIEDTTGVLDSWVGKDCCNGDWEGVQCNPATGKVTGLVLQSAVNEPTLYMKGTLSPSLGNLRSLELLLITGNKFITGSIPNSFSNLTSLRQLILDDNSLQGNVLSSLGHLPLLEILSLAGNRFSGLVPASFGSLRRLTTMNLARNSFSGPIPVTFKNLLKLENLDLSSNLLSGPIPDFIGQFQNLTNLYLSSNRFSGVLPVSVYSLRKLQTMSLERNGLTGPLSDRFSYLKSLTSLQLSGNKFIGHIPASITGLQNLWSLNLSRNLFSDPLPVVGARGFPSLLSIDLSYNNLNLGAIPSWIRDKQLSDINLAGCKLRGTFPKLTRPTTLTSLDLSDNFLTGDVSAFLTSLTNVQKVKLSKNQLRFDLSKLKLPEGVASIDLSSNLVTGSLSSLINNKTSSFLEEIHLTNNQISGRIPDFGESLNLKVLNIGSNKISGQIPSSISNLVELVRLDISRNHITGGIPQAIGQLAQLKWLDLSINALTGRIPDSLLNIKTIKHASFRANRLCGQIPQGRPFNIFPAAAYLHNLCLCGKPLPACRKTMK