wanglab/gogpt-training-data huggingface dataset:
Protein: Glutamate synthase [NADH] (EC 1.4.1.14) (NADH-GOGAT) (Q12680)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate.
Interaction partners:
- NADP-specific glutamate dehydrogenase 2
- NADP-specific glutamate dehydrogenase 1
- Glutamine synthetase
- Probable NADPH:adrenodoxin oxidoreductase, mitochondrial
- NAD-specific glutamate dehydrogenase
- Carbamoyl phosphate synthase arginine-specific small chain
- Multifunctional protein URA2
- Carbamoyl phosphate synthase arginine-specific large chain
- Amidophosphoribosyltransferase
- Isocitrate dehydrogenase subunit 1, mitochondrial
Sequence:
MPVLKSDNFDPLEEAYEGGTIQNYNDEHHLHKSWANVIPDKRGLYDPDYEHDACGVGFVANKHGEQSHKIVTDARYLLVNMTHRGAVSSDGNGDGAGILLGIPHEFMKREFKLDLDLDIPEMGKYAVGNVFFKKNEKNNKKNLIKCQKIFEDLAASFNLSVLGWRNVPVDSTILGDVALSREPTILQPLLVPLYDEKQPEFNETKFRTQLYLLRKEASLQIGLENWFYVCSLNNTTIVYKGQLTPAQVYNYYPDLTNAHFKSHMALVHSRFSTNTFPSWDRAQPLRWLAHNGEINTLRGNKNWMRSREGVMNSATFKDELDKLYPIIEEGGSDSAALDNVLELLTINGTLSLPEAVMMMVPEAYHKDMDSDLKAWYDWAACLMEPWDGPALLTFTDGRYCGAILDRNGLRPCRYYITSDDRVICASEVGVIPIENSLVVQKGKLKPGDLFLVDTQLGEMVDTKKLKSQISKRQDFKSWLSKVIKLDDLLSKTANLVPKEFISQDSLSLKVQSDPRLLANGYTFEQVTFLLTPMALTGKEALGSMGNDAPLACLNENPVLLYDYFRQLFAQVTNPPIDPIREANVMSLECYVGPQGNLLEMHSSQCDRLLLKSPILHWNEFQALKNIEAAYPSWSVAEIDITFDKSEGLLGYTDTIDKITKLASEAIDDGKKILIITDRKMGANRVSISSLIAISCIHHHLIRNKQRSQVALILETGEAREIHHFCVLLGYGCDGVYPYLAMETLVRMNREGLLRNVNNDNDTLEEGQILENYKHAIDAGILKVMSKMGISTLASYKGAQIFEALGLDNSIVDLCFTGTSSRIRGVTFEYLAQDAFSLHERGYPSRQTISKSVNLPESGEYHFRDGGYKHVNEPTAIASLQDTVRNKNDVSWQLYVKKEMEAIRDCTLRGLLELDFENSVSIPLEQVEPWTEIARRFASGAMSYGSISMEAHSTLAIAMNRLGAKSNCGEGGEDAERSAVQENGDTMRSAIKQVASARFGVTSYYLSDADEIQIKIAQGAKPGEGGELPAHKVSKDIAKTRHSTPNVGLISPPPHHDIYSIEDLKQLIYDLKCANPRAGISVKLVSEVGVGIVASGVAKAKADHILVSGHDGGTGAARWTSVKYAGLPWELGLAETHQTLVLNDLRRNVVVQTDGQLRTGFDIAVAVLLGAESFTLATVPLIAMGCVMLRRCHLNSCAVGIATQDPYLRSKFKGQPEHVINFFYYLIQDLRQIMAKLGFRTIDEMVGHSEKLKKRDDVNAKAINIDLSPILTPAHVIRPGVPTKFTKKQDHKLHTRLDNKLIDEAEVTLDRGLPVNIDASIINTDRALGSTLSYRVSKKFGEDGLPKDTVVVNIEGSAGQSFGAFLASGITFILNGDANDYVGKGLSGGIIVIKPPKDSKFKSDENVIVGNTCFYGATSGTAFISGSAGERFGVRNSGATIVVERIKGNNAFEYMTGGRAIVLSQMESLNAFSGATGGIAYCLTSDYDDFVGKINKDTVELESLCDPVEIAFVKNLIQEHWNYTQSDLAARILGNFNHYLKDFVKVIPTDYKKVLLKEKAEAAKAKAKATSEYLKKFRSNQEVDDEVNTLLIANQKAKEQEKKKSITISNKATLKEPKVVDLEDAVPDSKQLEKNSERIEKTRGFMIHKRRHETHRDPRTRVNDWKEFTNPITKKDAKYQTARCMDCGTPFCLSDTGCPLSNIIPKFNELLFKNQWKLALDKLLETNNFPEFTGRVCPAPCEGACTLGIIEDPVGIKSVERIIIDNAFKEGWIKPCPPSTRTGFTVGVIGSGPAGLACADMLNRAGHTVTVYERSDRCGGLLMYGIPNMKLDKAIVQRRIDLLSAEGIDFVTNTEIGKTISMDELKNKHNAVVYAIGSTIPRDLPIKGRELKNIDFAMQLLESNTKALLNKDLEIIREKIQGKKVIVVGGGDTGNDCLGTSVRHGAASVLNFELLPEPPVERAKDNPWPQWPRVMRVDYGHAEVKEHYGRDPREYCILSKEFIGNDEGEVTAIRTVRVEWKKSQSGVWQMVEIPNSEEIFEADIILLSMGFVGPELINGNDNEVKKTRRGTIATLDDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASVDKFLMDGTTYLPSNGGIVQRDYKLLKELASQV
Protein: Nanos homolog 1 (NOS-1) (Q80WY3)
Organism: Mus musculus (Mouse)
Function: May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion (By similarity). Not essential for normal development.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8WY41}. Cytoplasm {ECO:0000250|UniProtKB:Q8WY41}. Note=Colocalizes with SNAPIN and PUM2 in the perinuclear region of germ cells. {ECO:0000250|UniProtKB:Q8WY41}.
Interaction partners:
- CCR4-NOT transcription complex subunit 1
- Pumilio homolog 2
- Pumilio homolog 1
- Protein Smaug homolog 2
- Dead end protein homolog 1
- Tudor domain-containing protein 7
- Deleted in azoospermia-like
Sequence:
MEAFPWAPRSPRRARAPAPMALVPSARYVSASGPVHPQPFSSWNDYLGLATLITRASDRGSPHEGPGPTAAGPTMGPPEDDEDDDGEEPEAGGRYLGGALELRALELCAGPAEPGLLEERFAELNPFAGRAAAVLLGCAPTASTTAAAASTAEVTPREEPSPAWAAEPRLHAASGATAARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLSKVPPPTVRPPPRSNRDSLPSKKLR
Protein: Uncharacterized protein (Q38CE7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable eukaryotic initiation factor 4A
- Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein
- FACT complex subunit
- Histone H3, putative
- Histone H3 variant
- Uncharacterized protein
Sequence:
MQNVILAHDGSVVAPRRYSTTQQQTAQQPSSSTHSTRNQKHHHQQLQQQSDADDNCAYLQRHCIPSKVEGLFSNVLNDLPNDPLLHIVEQLRASNNSNNLSNGGNPPNHSKQATNESIREGATGSGTTEGKEPVPPTTPCAPFTRTALVSEGLNPEPPTRGNNPVSGAEDPFVHSMNVATESGCRPVGENLNTPPASVDAAGLSLANATPTTTPLTTSATPSVTTCESMNAFTLASGRARTPTPPAFSELSCTNYRGSVNGARPATHAMRPSSRGSSRNEVVQGVCGVRFGATNDIFYGGPMPPTLDRDESTRSDLSAFSVASMDLQDFLQEFRSAKVESVGAEAKMVDINALSDIIQNVNIPLPDTPIIADLFDEVRNIAALRYDTEASPDQANDMECQKRISATTTVVTGSESNLIDCIYFEAFLARMAFMIQGRYPMEVLRGTFYSIGESARQKPSADGAAQPSSVTPPQTTQQQQQQKVCAEDIRGPSTSSFGVASRPYRVAAKSGCRNSNSGALSADSSSNTHTSPTVIPTTAACPINCSAAEQAAEPSALLNGVPLAICVEEGLWRGLGLPATREEVERALHTLGIPVDGNYKCHVNDFVRLVTVLTSGGMSGLSCEKTSPWGPVGIGRESSFLQQPQE
Protein: Pi-ta protein (Q84UB1)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MAPAVSASQGVIMRSLTSKLDSLLLQPPEPPPPAQPSSLRKGERKKILLLRGDLRHLLDDYYLLVEPPSDTAPPPDSTAACWAKEVRELSYDVDDFLDELTTQLLHHRGGGDGSSTAGAKKMISSMIARLRGELNRRRWIADEVTLFSARVKEAIRRQESYHLGRRTSSSRPREEVDDDDREDSAGNERRRFLSLTFGMDDAAVHGQLVGRDISMQKLVRWLADGEPKLKVASIVGSGGVGKTTLATEFYRLHGRRLDAPFDCRAFVRTPRKPDMTKILTDMLSQLRPQHQHQSSDVWEVDRLLETIRTHLQDKRYFIIIEDLWASSMWDIVSRGLPDNNSCSRILITTEIEPVALACCGYNSEHIIKIDPLGDDVSSQLFFSGVVGQGNEFPGHLTEVSHDMIKKCGGLPLAITITARHFKSQLLDGMQQWNHIQKSLTTSNLKKNPTLQGMRQVLNLIYNNLPHCLKACLLYLSIYKEDYIIRKANLVRQWMAEGFINSIENKVMEEVAGNYFDELVGRGLVQPVDVNCKNEVLSCVVHHMVLNFIRCKSIEENFSITLDHSQTTVRHADKVRRLSLHFSNAHDTTPLAGLRLSQVRSMAFFGQVKCMPSIADYRLLRVLILCFWADQEKTSYDLTSIFELLQLRYLKITGNITVKLPEKIQGLQHLQTLEADARATAVLLDIVHTQCLLHLRLVLLDLLPHCHRYIFTSIPKWTGKLNNLRILNIAVMQISQDDLDTLKGLGSLTALSLLVRTAPAQRIVAANEGFGSLKYFMFVCTAPCMTFVEGAMPSVQRLNLRFNANEFKQYDSKETGLEHLVALAEISARIGGTDDDESNKTEVESALRTAIRKHPTPSTLMVDIQWVDWIFGAEGRDLDEDLAQQDDHGYGFFILFPGYNLQGLLSFFLSLPWLLSLPSMHLQPDLMIV
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (Q49HH8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MQKALKKYFVSMDEYLASIGLYRKMMARDASCLFRAVSEQLYYSQNYHQRIRKECVNFIRANRCNFEPFVEGSFEKYLERLEDPKETVGQVIIKALSLLYRRCFVIYRYPGKPPTEIAEEDNLPKILLCCSNNGHYDIVYPKSYPVDAAVCQALLYELLYTRVLGVEDDEIQAALEGFKGGGRRYRNSHSMCSEDASYDTPEDRSQSDFFREDWESRGHCRFDDRPRVGAEDQKVTEGSGKLALPYKVLKALEPELYRNVEFDVWQDSRKELQKTDYMVFAGRQYFLGDKCQVRLDPKGKYYNAFIQEVGTHSTAVTVFIEELGEKHLVSLTNLKPVNPVPAWNITPSRKGNSYSHAEQYPGELDPELRGRRRFFKKPRGVHSPAPPPPGLIYEHYRPHPPPRQPRGYGPPSSARFLNRHHLIGPDMAYYPSPSKRCYQSLDNYSFRSRRSRRQMHTLNKECLSCVPEPGEETQDMEGSITFYELEETDEGAFSPISGQAVSSPMVPGATAYWVPRVPSPIPPSGKQAMTSSEEDPDERSAGGDQGEYSEEYIYSAAEAGYQSPSVYAAAAESTTNLTIQEGSSRAGSPQEGVATYSYSQQVVVKSSVLSSSQPINSAPAAIFTSNSSSSSTGSSQTPPNSLQPNNILTPGQLPPGRPAVPWFVNELGEPVAMAPPPPYSYDPNGSDLPRDCKVLQYYYNLGVQWYQQSYWHSMVHLQQVYPHQAADAQFQSYQSTAPPADHTVPQAYPDSVRMCPHPQGDMPSNGAPLGMENPPTVVPGTVFYPVVQEQCGQPALHSTYDPYMPVLSTTYHYLTPWTPGAAPHSRFHHTTYCPSSSHPPVNYITAPGHPNHLPHSQFV
Protein: Delta and Notch-like epidermal growth factor-related receptor (Q8NFT8)
Organism: Homo sapiens (Human)
Function: Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Subcellular location: Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). {ECO:0000250}.
Interaction partners:
- E3 ubiquitin-protein ligase DTX1
- Zinc finger protein ZIC 4
- Amphiphysin
- Presenilin-1
- Leucine-rich glioma-inactivated protein 1
- Paraneoplastic antigen Ma2
- Rho GTPase-activating protein 26
- Recombining binding protein suppressor of hairless
- Dihydropyrimidinase-related protein 5
- IgLON family member 5
Sequence:
MQPRRAQAPGAQLLPALALLLLLLGAGPRGSSLANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGRLVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRISRIEYQGSSRPAYEEFYNCRSIDSEFSNAIASIRHARFGKKSRPAMYDVSPIAYEDYSPDDKPLVTLIKTKDL
Protein: Protostome-specific GEF, isoform E (Q7KVY9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ubiquinol-cytochrome c reductase complex assembly factor 5
- Peripheral plasma membrane protein CASK
- Ras-related protein Rab-3
- Juvenile hormone acid O-methyltransferase
- Uncharacterized protein, isoform B
- Guanine nucleotide-binding protein subunit alpha
Sequence:
MPTMTRMHRHSSSSAVVEESRGRRRGVGVPGVGDANKENFGVHFMSSPFGNASLIALQDLSNVHGKSPQRRSFSEGSGPRQATPQLAALRCLPRTTGGAVALEDSQLSSSRMGDTTLDRMLDAIIESARKEVRCTKTLPGAGATTSTTILADNAEWSETSVHEMEVRTPTHLKRQRVVRRKNPHKTTTINQTQSHQAKKLEPLQLVPSTKRCLSFSSSSASSDLDEDEQQVAKRSSLASPTTTPPSHCTTTTSSISSSSSSNGGADMEASQRGSIDVSIAFDAKEQQLNVHVIRCRDLQRSHGSGNGSINAYVKVALSGGAQPPGYGGHSSGGSMSSGYQRTAVHRHSGRPYFDQRFNFQISSGEETAGQYLQLAVWHRDRHLNSVPVTQSEWQARVKSGTERRTAERLAKLENAGNEAKRSEFLGCSTFPLNELVHPDSGVSAGSYKLHAQACPPPTSRHSQPKANAGQDQKQETEAAKDQDKQQDDSPAEMAAAVTVTPQKPVATGSGSGSNSAAMALNDEVISISIDSMGKEDPLLPQQPQQPMKLSKKALHQRDADENLFLRFLELDPPADGNANSTTTQAQATGSQSSASKANESNANHLNNGTSGGRRQSTMPNSGGSSVGGAVRQQQGRTPFTMTKRLTRTEERGFGFSIVWTHPPRVEKIEAGLSADRCGILPGDYVIFVDKHNVVTMPEADVLNLIRSQGSSLTLEIFRRSGAGATTITSTDLGQNNVHISTRLGAAVGLGSEEHTLATTATGTTTVMSLQRTTSTRIQPLANSMSRPATACSGTTSSIEAAKRRLHLPQVTFSKESIVPVTDNRRRFLLQLISREQNFTAALHFGVDRFVQPLGERKDLISPNDHRTLFQNIDELLRIAEDILEQLCSSDQQDQEPQMNFASRVYLSKTTAICAAYKKYCNGIKRADCVLVNKSRQTGSEFIAFITEPAVPRKRPDLTMFIHRPLQHFREILKLMQLLAGNCHVDTEEHKNFSTVINELQAAYREITVSSGLMEPLGEGRPLLTLQDLESRMVFTKCKPFTLAVQGRQWIFGGDLSRVEGRSVKPYWTLLFSDIIVFAKVSRDRVLFITEEPIPIANVVDSCFHMRKKTTEFRLTVDPNGRLAESPTGYCAPDLTRTPKRGARRKSLILRAPSLELKAVWQNLLQRQIFLVNAALGSTPLSSPLDSPDVLNTLVPLSDIGLTTASMGSMKLPSLDSIHLKQQQKQQRTNNSHGHVHSATGVATDRTADRSHGHNHGIHGGHVEQIELLIDEKCRILNKTGTPKSSALHLANWMKGQLDKQQQQARLAAIARSQENVSAEDEQLIFNSDSEQDERITYWTRQQLEKRTKELNLAKENGGLSARPNFGGKRLSGVEELSMSATSDIYSTSEAEGVTSVISQSHSTTSDSQITVRSSPIVLDKLAVCRHCHKNCQQSGPGGARPGGGGGVNNSSSTPVLLCNSLKVQHSQSSPNRCCKLSNGIAGATEMANPKNSNRTGTGTGSVTSMSSSTITGELSSKVVASSSRRETGDTESDVAQLITDEISQSQSEATDDSVGAMPNSSRSAGEGNPVITGSRLRHLDPPVSVSSLPNGHCSAGVGGGSPKPLPPPRRTRVVAQMCQEPPRPKANQQVKAIVTITETARIMRSSPTKGSGSGSATGTGSVGGSPAKYAACHCRCTPEDFTHAQLSPDKMEHQTCKLLESPKQTTTTLEQKQEDEQLSLMLIGLAQLAPAATLCGQERIPKEENSTPTIAVVPPTPDSVLTKTSTHVWDNSGCSSNGGGTSTTSTATTTTKQPRQAIIENIPEDSCDESPLDEEPPYRPMSSALRRFGTMSSLEKLPSDDRMDEADELDDDLDSFKPNGHDGNSPQNEEDDEDADSERALVQNDLGASSSSGVIVNGEGLASGAWTNRAGAYVSDKMSFFEESRAFIDKYLGRWNAGDAQQQHQQGTASETDEQMDECTSGATSGEEVWGTPTSGGDNDDQDLQLINSENTHSSPTKSSTSLNDDDDTELMMDELLMAPPMTASTIRGLLPRFYRRRLEPLFEEETESDEEKTQQDSDDIKKGEATTNGHYLEDSAGSSSDSESVPPAPPLVPRPVVPDREEDPSAEGQQENLAMEDQEDLHSSVERLLPNLATSAMGPRPLLTTRLLPTTAIDPQPPAVLVASSCEYLLDQRPSSVPGRDLAGGSIGTTTMTSSRPTPLSPAKAAATPIGMNATMTTKTTTTTMMTPSRAPSSTISTISSASDTTSSGGRASGRPPRFVPPPPPPRRLLLTQTDLIAGQAKTELPRKKSGATADSGCSVAVGDAASASDPTAIGSRTMPSTPSTSSLASAVAPKRPSSTIIETCLLGAPRPASATSSATASRMAKPIRQSPPTQHQSQPRGQSCPAAVPAPSTAAPDAPTVPMPHAGCGLSPRLEMRLALNHDILGDEDLICYEPGPDLTTILGHDLSTFHRLTGRDLLSRSATNRVQPKEAVISYSQQRNSKMDTPTVNRRPRPLSAGALGGSTSNSNPNNSRSSSSHGNSPLGGGLTRAGVEPVGQQQLVVQAGGGSAGRVGGGSGSAGGNSTACSSNRGGSKLGDLEILARREKIYSMSQSRSGCRVRETTSTTTLMAMATEMRSGMDSEKRDSSWPKRAAAAASLTRTRSSTSMDGAGAISTTTTTTTTMTEEAFLETEVGRSKRLINFIKRRNSEITASSTSSTPNFSDGAIGEQPQPSHSQSSLLLQKLPPGQSQAQDSVEMAQMSPRKDNDKPSLNRRLWKQITKRRRTNSVSQIVAG
Protein: Transcriptional regulator, TetR family (Q88KZ5)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Interaction partners:
Sequence:
MAQSETVERILDAAEQLFAERGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLERELERRQAKPEHKPSLEELLEMLVEQALAVQPRSNNDLSIFMRLLGLAFSQSQGHLRRYLEDMYGKVFRRYMLLVNEAAPRIPPLELFWRVHFMLGAAAFSMSGIKALRAIAETDFGINTSIEQVMRLMVPFLAAGMRADSGVTDEAMATAQLRPRTKTGSATAKA
Protein: Glycogen [starch] synthase isoform 1 (EC 2.4.1.11) (P23337)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Is believed to regulate the synthesis of glycogen.
Interaction partners:
- Glycogenin-1
- Glycogenin-2
- Glycogen [starch] synthase isoform 2
- 1,4-alpha-glucan-branching enzyme
- UTP--glucose-1-phosphate uridylyltransferase
- Trehalose-phosphatase
- Glycogen phosphorylase
- Alpha,alpha-trehalose-phosphate synthase 56 kDa subunit
- Trehalose synthase complex regulatory subunit TSL1
- Trehalose synthase complex regulatory subunit TPS3
Sequence:
MARDLQNHLLFEVATEVTNRVGGIYSVLKSKAPVTVAQYGDNYTLLGPLNKATYESEVEKLDWEDESIFPEELLPIQKTLMSMREKGVNFVYGNWLIEGAPRVILFELDSVRHFLNEWKADLWSLVGIPSPEHDHETNDAILLGYVVVWFLGEVSKLDSSHAIIGHFHEWLAGVALPLCRKKRIDVVTIFTTHATLLGRYLCAAGDVDFYNNLQYFDVDQEAGKRGIYHRYCIERAAAHTADVFTTVSQITALEAEHLLKRKPDGILPNGLNVVKFQAVHEFQNLHALKKDKINDFVRGHFHGCFDFDLDNTVYFFIAGRYEYKNKGADMFIESLARLNYRLKVSGSKKTVVAFLIMPAKTNSFTVEALKSQAIVKSLENTVNEVTASIGKRIFEHTMRYPHNGLESELPTNLDELLKSSEKVLLKKRVLALRRPYGELPPVVTHNMCDDANDPILNQIRHVRLFNDSSDRVKVIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETDQAKDYGIYIVDRRFKSPDESVEQLADYMEEFVNKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLGLRRAYPEQFKQLVGETISDANMNTLAGGKKFKIARPLSVPGSPKVRSNSTVYMTPGDLGTLQDANNADDYFNLSTNGAIDNDDDDNDTSAYYEDN
Protein: Serine/threonine-protein kinase BLUS1 (EC 2.7.11.1) (Protein BLUE LIGHT SIGNALING 1) (O23304)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ser/Thr protein kinase mediating a primary step for phototropin signaling in guard cells. Essential for stomatal opening.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:23811955}.
Interaction partners:
- DnaJ protein ERDJ2A
- Translocation protein SEC62
- ATPase 5, plasma membrane-type
- Protein PHYTOCHROME KINASE SUBSTRATE 4
- Serine/threonine-protein phosphatase PP1 isozyme 1
- Guard cell S-type anion channel SLAC1
- ABC transporter B family member 19
- Root phototropism protein 2
Sequence:
MARNKLEFPLDAEAYEIICKIGVGVSASVYKAICIPMNSMVVAIKAIDLDQSRADFDSLRRETKTMSLLSHPNILNAYCSFTVDRCLWVVMPFMSCGSLHSIVSSSFPSGLPENCISVFLKETLNAISYLHDQGHLHRDIKAGNILVDSDGSVKLADFGVSASIYEPVTSSSGTTSSSLRLTDIAGTPYWMAPEVVHSHTGYGFKADIWSFGITALELAHGRPPLSHLPPLKSLLMKITKRFHFSDYEINTSGSSKKGNKKFSKAFREMVGLCLEQDPTKRPSAEKLLKHPFFKNCKGLDFVVKNVLHSLSNAEQMFMESQILIKSVGDDDEEEEEEDEEIVKNRRISGWNFREDDLQLSPVFPATESDSSESSPREEDQSKDKKEDDNVTITGYELGLGLSNEEAKNQEGEVVGFDKDLVLEKLKVLKKSLEHQRARVSIIIEALSGDKEEKSREEELLEMVEKLKIELETEKLKTLRADKDSVLG
Protein: Dystrobrevin beta (DTN-B) (mDTN-BDTN-B) (Beta-dystrobrevin) (O70585)
Organism: Mus musculus (Mouse)
Function: Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids. May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20530487}. Postsynaptic density {ECO:0000250|UniProtKB:P84060}. Cell projection, dendrite {ECO:0000269|PubMed:11585924, ECO:0000269|PubMed:16540561}. Basal cell membrane {ECO:0000269|PubMed:10893187}. Postsynapse {ECO:0000269|PubMed:16540561}. Nucleus {ECO:0000269|PubMed:20530487}. Note=Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells. {ECO:0000269|PubMed:16540561}.
Interaction partners:
- Alpha-1-syntrophin
- Beta-2-syntrophin
- Dystrophin
- Beta-1-syntrophin
- Dystroglycan 1
- Dysbindin
- Gamma-2-syntrophin
- Protein phosphatase 1 regulatory subunit 21
- Gamma-1-syntrophin
Sequence:
MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHLVPPRPLTNMNDTVVSHMSSGVPTPTKRLQYSQDMPNLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGAEAEEQAGTEKTREGLPPRGTFLSVFLLHTWTKLAGCQTHSTSRERSQAYGKWGGTA
Protein: Distal tail protein (Dit) (Gene product 19.1) (Gp19.1) (O48459)
Organism: Bacillus phage SPP1 (Bacteriophage SPP1)
Function: Forms a 40 Angstroms wide channel at the distal tip of the tail. Remains associated to the tail after DNA ejection.
Subcellular location: Virion {ECO:0000269|PubMed:20843802}.
Interaction partners:
Sequence:
MNIYDILDKVFTMMYDGQDLTDYFLVQEVRGRSVYSIEMGKRTIAGVDGGVITTESLPARELEVDAIVFGDGTETDLRRRIEYLNFLLHRDTDVPITFSDEPSRTYYGRYEFATEGDEKGGFHKVTLNFYCQDPLKYGPEVTTDVTTASTPVKNTGLAVTNPTIRCVFSTSATEYEMQLLDGSTVVKFLKVKYGFNTGDTLVIDCHERSVTLNGQDIMPALLIQSDWIQLKPQVNTYLKATQPSTIVFTEKFL
Protein: Voltage-gated inwardly rectifying potassium channel KCNH6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (hERG-2) (hERG2) (Potassium voltage-gated channel subfamily H member 6) (Voltage-gated potassium channel subunit Kv11.2) (Q9H252)
Organism: Homo sapiens (Human)
Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q12809}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q12809}.
Interaction partners:
- Sigma non-opioid intracellular receptor 1
- 3-beta-hydroxysteroid-Delta
- Voltage-gated inwardly rectifying potassium channel KCNH2
- Potassium voltage-gated channel subfamily A member 4
- Transcriptional regulator ERG
Sequence:
MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVMQQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKCSSRSLSQRLLSQSFLGSEGSHGRPGGPGPGTGRGKYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESRRGACSYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAAIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNVERPYLEHKIGWLDSLGVQLGKRYNGSDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDDVVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYPAFAESFWSKLEVTFNLRDAAGGLHSSPRQAPGSQDHQGFFLSDNQSDAAPPLSISDASGLWPELLQEMPPRHSPQSPQEDPDCWPLKLGSRLEQLQAQMNRLESRVSSDLSRILQLLQKPMPQGHASYILEAPASNDLALVPIASETTSPGPRLPQGFLPPAQTPSYGDLDDCSPKHRNSSPRMPHLAVATDKTLAPSSEQEQPEGLWPPLASPLHPLEVQGLICGPCFSSLPEHLGSVPKQLDFQRHGSDPGFAGSWGH
Protein: Basic leucine zipper 9 (AtbZIP9) (bZIP protein 9) (Basic leucine zipper OPAQUE 2 homolog 2) (Basic leucine zipper O2 homolog 2) (Q9FUD3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Basic leucine zipper 1
- bZIP transcription factor 17
- At2g37950
- Basic leucine zipper 8
- Transcription factor HY5
- bZIP transcription factor 28
- bZIP transcription factor 49
- Basic leucine zipper 34
- Basic-leucine zipper
- Transcription factor HY5-like
Sequence:
MDNHTAKDIGMKRSASELALQEYLTTSPLDPCFDLMNRDYTCELRDSLLWSEGLFPAGPFRDAQSSICENLSADSPVSANKPEVRGGVRRTTSGSSHVNSDDEDAETEAGQSEMTNDPNDLKRIRRMNSNRESAKRSRRRKQEYLVDLETQVDSLKGDNSTLYKQLIDATQQFRSAGTNNRVLKSDVETLRVKVKLAEDLVARGSLTSSLNQLLQTHLSPPSHSISSLHYTGNTSPAITVHSDQSLFPGMTLSGQNSSPGLGNVSSEAVSCVSDIWP
Protein: Ankyrin 2 (A0A5K1VW73)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
EHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKDNNE
Protein: Ca(2+)/H(+) antiporter (ApCAX) (Q75XW3)
Organism: Aphanothece halophytica
Function: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Plays an important role in salt tolerance. Does not transport sodium or lithium.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:14559898}; Multi-pass membrane protein {ECO:0000269|PubMed:14559898}.
Interaction partners:
Sequence:
MLNKNTIFFGLLLFIPISLLGHWLHWDEVSIFLTASLAIIPLAAFMGEATEEIAIVVGPTLGGLLNATFGNATELILAFIALKSGLISVVKATITGSIISNLLLVMGFAMLLGGLRYKEQVFQSEVARVNASSMNLAVIAILLPTAVEHTSNGIGEETLQTLSVAVAIVLIIVYGLTLLFSMKTHSYLCEVGEIDQQSSSAMESGDKIPEKKPEDVNLWFWLGILLVVTITVAIESELLVNSLESATESLGLTALFTGVILLPVIGNAAEHFTAVTVAMKNKMDLSLSVAVGSTLQIALFVAPVLVIAGWIMGQPMDLDFNPFELVAVAVSVLIANSISSDGKSNWLEGSLLLATYIVIGLAFFFHPVVPEIG
Protein: Acyl-CoA synthetase family member 3 (F5H362)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKT
Protein: Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1) (Q13522)
Organism: Homo sapiens (Human)
Function: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Protein kinase C alpha type
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit gamma
- Protein phosphatase 3 catalytic subunit alpha
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Sequence:
MEQDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSV