wanglab/gogpt-training-data huggingface dataset:
Protein: Target of rapamycin complex 2 subunit ste20 (TORC2 subunit ste20) (Q09743)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cell survival under various stress conditions. TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Positively regulates amino acid uptake through the control of expression of amino acid permeases.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Target of rapamycin complex 2 subunit sin1
- Target of rapamycin complex subunit wat1
- Serine/threonine-protein kinase tor1
- Target of rapamycin complex 1 subunit mip1
- Serine/threonine-protein kinase tor2
- Target of rapamycin complex 2 subunit bit61
- Target of rapamycin complex 1 subunit tco89
- Exosome complex exonuclease rrp6
- Tuberous sclerosis 1 protein homolog
- Target of rapamycin complex 1 subunit toc1
Sequence:
MKPVRRGQTDTALDISSHAKTNGDFIKKMNTTDSKRLKLLEDLKGKLEVECKIRDGAETLLQVFDTNFKKETKERKEMLKKKCTDELESSKKKIEELVSSIESFQGENGEAKTGSTSLTRSASATVSRKSSLQEKYSTRFSYKAGCSDSCSVTVSGTGELIGPTRNAHSNLTPTVIQRIDFENVNEKNNSSSEDTQPNGKRPSSLQSNFSQFPLNPWLDNIYKACLEGSMKDVIDSSNNLCEYLHEHSDPAYAKNFSLITPTILSMLELNVSEVTASVYRLLRHLFLDATAFSCCQMLNLPWILSKSLLSGTDAYQIEREQAFRLIRTLYFLSSTEGHEDYLSGITRTIISICEHVSDVSRGIAVETLIELMIIRPKILFKANGLRVLMISLIDGSISENLAASAALALVYLLDDPESACYVNLPYDIGILLSPFTSSSSRDTFNSSEEQSEQAAKAMKSSAKVASVLLNSWSGLLALSTNDFQALRSIVDTLRVPSFAPRSDVIDLFFLIFQVEYSSWSESFLAGKRLTVVKNQAVSNDDNINMVNIPDGSNKKYMSLRQHFTAVLLFIFLELGLVESIVCMIRASDDPSASRKATYLLGEVLRLSDELLPIHLGAKIQSLPSLFNMASQFTAEDRFVATSVLQSIESLNRVKFHSATQPFSQTTSLLFKEQKTDGSFRGQRQVEHVKLKMGMQIDDSHFRSMLAETNVLATKNYQKWRWDTLVQIMEGPLLSPKRIDETLRTTKFMRRLLAFYKPFSNRFSSIQNTKPNQKFIKVGCLVFRTLLANPEGVKYLSESKVIKQIAESLSQIDGYSEQVSEPIFSNSRLQKTLTHGYFPMLKVLSSQKEGHAIMERWRIFTTLYHLTELRNRDDLIIIFLTNLDYRLEGHTRIIFSKALNTGQQAVRLTATKHLAALINSESANDNLNHWAISLLIFQLYDPCLEVCKTAVKVLNEVCARNENLLAQVVQLQPSLAHLGEIGSPLLLRFLATTVGFHYLSEINFIEHELDNWYHHRNIDYVDLLEQNFFLSFVSNLKIIDKKNNEPDENILPLHFYGELVKSPQGCEVLESSGHFESFMGTLVEFYDKPLGNEAIRQLKSALWAIGNIGKTDQGITFLINHDTIPLIVKYAENSLIPTVRGTAYFVLGLISRTSKGVEILESLHWYSLMSLMGTSQGICIPRHAGQVLSTPRRNVEFVNERVPTPEFSSLLSSLTNSEREVIRLVSNLSNHVLTNESARQLTKIRSKNAKVFSSKRLVKACMTILGKFHYRVQIQQFVFELFPYSVLLSSSTSQDLNESPSRPNNLSISA
Protein: Eukaryotic translation initiation factor 5A-2 (eIF-5A-2) (Q9UST4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation (By similarity). Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable deoxyhypusine synthase
- Deoxyhypusine hydroxylase
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL13
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS19B
- Small ribosomal subunit protein uS5
Sequence:
MGMFIQKEHKPTMAEEEHVDFEGGEAGASLTFPMQCSALRKNGHVVIKGRPCKIVDMSTSKTGKHGHAKVHIVALDIFNGRKYEDMSPSTHNMDVPVVKRDEYQLVNIDDGYLNLMTTDGTTKDDVRLPEGELGNEIEEGFEEGKDLIITVVSAMGEEIALACRDAPSA
Protein: Heparan-sulfate 6-O-sulfotransferase 1-A (HS 6-OST-1A) (HS6ST-1) (EC 2.8.2.-) (Q56UJ5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Heparan-sulfate 6-O-sulfotransferase 1-B
- Heparan sulfate 2-O-sulfotransferase 1
- [heparan sulfate]-glucosamine N-sulfotransferase
- Sulfotransferase
- Sulfotransferase
- Prokineticin
- Prokineticin receptor 1b
- Exostosin-like 3
- NMDA receptor synaptonuclear signaling and neuronal migration factor
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
Sequence:
MNLLTGRNMVERSSKFLFIVVGSVLFMLILYQYVAPGMMNFGSPHGYMLEDDADLFPTPDPHYVKKFYFPIRDLERTVDFEIKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKKESRMKNQRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNMSFIPEKKRAQVLLESAKKNLRDMAFFGLTEFQRKTQYLFERTFRLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMQLYDYARDLFQQRYMYKRQLERREQRLKNQPLFPFRRTSSSDSTFRDDAPESEGSRLPTEDYMNHIINRW
Protein: Small ribosomal subunit protein uS2A (40S ribosomal protein S0-A) (Nucleic acid-binding protein NAB1A) (P32905)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uS2 is required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14627813, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein eS1A
- Small ribosomal subunit protein eS4A
- Small ribosomal subunit protein uS11B
- Small ribosomal subunit protein eS10A
- Small ribosomal subunit protein eS27A
- Small ribosomal subunit protein uS14B
- Large ribosomal subunit protein uL15
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein uL18
- Eukaryotic translation initiation factor 3 subunit A
Sequence:
MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTFGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRDPEEVEQQVAEEATTEEAGEEEAKEEVTEEQAEATEWAEENADNVEW
Protein: Left-right determination factor (Q9W6I7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|PIRNR:PIRNR037402}.
Interaction partners:
Sequence:
MALFIQLFILTTAISLTQGFQHEDIKQALLQKLGLTEPPRIQKRDLENLVVPAHIKSKYLSMLKLHHQRRRRSLPSLAGILRGIHGNADITGEIKYSDTTRQRLVFDMEARLQENTEVTMAELKLFQTAAQSPSKPERRHHRPINHARVSIYWVEVLENGSNRTSLLDSRLVPIHESGWRSFDVTQAIHYWSKSQKKAPLHLEVWTEGERPGSYAAEMAKRVRFATQDPKENTLEKDMGAPELVLYTLDLDEYGSQGNCNSSPNSSKCCREEHFINFRELTWTQYWIIEPAGYQAFRCAGGCKQPKRGFYGYGQRTCAVMESAPLPMMYLVKKGDYTEIEVAEFPNMIVEKCGCSMDKIPPV
Protein: Large ribosomal subunit protein uL2 (60S ribosomal protein L8) (Q9V3G1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm.
Interaction partners:
- Small ribosomal subunit protein eS17
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein uL18
- GEO07453p1
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS7A
- Large ribosomal subunit protein uL14
Sequence:
MGRVIRAQRKGAGSVFKAHVKKRKGAAKLRSLDFAERSGYIRGVVKDIIHDPGRGAPLAVVHFRDPYRYKIRKELFIAPEGMHTGQFVYCGRKATLQIGNVMPLSQMPEGTIICNLEEKTGDRGRLARTSGNYATVIAHNQDTKKTRVKLPSGAKKVVPSANRAMVGIVAGGGRIDKPILKAGRAYHKYKVKRNSWPKVRGVAMNPVEHPHGGGNHQHIGKASTVKRGTSAGRKVGLIAARRTGRIRGGKGDSKDK
Protein: DAZ associated protein 1 (K7EQ55)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNNSGADEIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASRPHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRSDNSKSNKIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMHFHDIMGKKVEVKRAEPRDSKSQAPGQPGASQWGSRVVPNAANGWAGQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPPGGFPPPQGFPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQPDFPYGQYGYGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGPPAGGSGFGRGQNHNVQGFHPYRR
Protein: rRNA-processing protein UTP23 (U three protein 23) (U3 small nucleolar RNA-associated protein 23) (U3 snoRNA-associated protein 23) (Q12339)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in rRNA-processing and ribosome biogenesis.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095}. Nucleus, nucleolus {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14690591}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 5
- KRR1 small subunit processome component
- Something about silencing protein 10
- U3 small nucleolar RNA-associated protein 14
- U3 small nucleolar RNA-associated protein 11
- ATP-dependent RNA helicase ROK1
- Nucleolar protein 58
- Ribosomal RNA small subunit methyltransferase NEP1
- 13 kDa ribonucleoprotein-associated protein
- rRNA biogenesis protein RRP5
Sequence:
MRQKRAKSYRKQLLVYSHTFKFREPYQVLVDNQLVLECNNSNFNLPSGLKRTLQADVKVMITQCCIQALYETRNDGAINLAKQFERRRCNHSFKDPKSPAECIESVVNISGANKHRYVVASQDIDLRRKLRTVPGVPLIHLTRSVMVMEPLSTASAKASKITEEQKLYKGLNDPNIEKLQESGDGSGKESITKKRKLGPKAPNPLSVKKKKKVNSPSDEVKDKEDTSKEKKKRRRRKHKSNTNVPVSNGTTAAQ
Protein: Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) (B5D5N9)
Organism: Rattus norvegicus (Rat)
Function: Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). The affinity for its substrates differs between isoforms created by alternative splicing. May play a role in classical or alternative activation of macrophages via its role in arginine transport.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P18581}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P18581}.
Interaction partners:
- Amino acid transporter
- Neutral amino acid transporter B
Sequence:
MIPCRAVLTFTRCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATMTAGVISAVMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYEQPKYTPEKDILESCTNATSKSESQVTMLQGQGFSLRTLFNPSALPTRQSASLVSFLVGFLAFLIAGLSILTTYGVQAIARLEAWSLALLALFLVLCAAVILTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMVLGFLIYFAYGIRHSLEGNPRDEEEDEDVCPDNVNAAAEEKSAMQANDHHQRNLSLPFILHEKTSEC
Protein: Probable G-protein coupled receptor 34 (Q9UPC5)
Organism: Homo sapiens (Human)
Function: Orphan receptor.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27086875}; Multi-pass membrane protein {ECO:0000269|PubMed:27086875}.
Interaction partners:
- EF-hand domain-containing family member C2
- Transmembrane protein 119
Sequence:
MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFKPGYSLHDTSVAVKIQSSSKST
Protein: Protease A inhibitor 3 (Proteinase inhibitor I(A)3) (Proteinase yscA-inhibitor) (Saccharopepsin inhibitor) (P01094)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Specific and potent inhibitor for yeast aspartic protease A (yscA). The proteinase acts as a folding template stabilizing the helical conformation in the inhibitor, which results in the potent and specific blockage of the proteolytic activity.
Interaction partners:
- Saccharopepsin
- Protein SIP18
- Uncharacterized protein YHR138C
- Protein GRE1
Sequence:
MNTDQQKVSEIFQSSKEKLQGDAKVVSDAFKKMASQDKDGKTTDADESEKHNYQEQYNKLKGAGHKKE
Protein: Small ribosomal subunit protein uS15 (40S ribosomal protein S13) (P28189)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL6
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein eL29
- Small ribosomal subunit protein eS27
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL14
Sequence:
MGRMHSKGKGIASSALPYVRSPPAWCKADADSVVEQILKFSKKGMSPSQIGVTLRDSHGIPQVRFITGQKIMRILKANGLAPELPEDLYNLIKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLARYYRKVGALPPTWKYESATASALVA
Protein: Serine-threonine kinase receptor-associated protein (Q386X0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable eukaryotic initiation factor 4A
Sequence:
MNNRHSGSEKTPATQKKDSLAPSATNADITKVKICSGHTRPICHINYSNIIDGTFWLVTSCHDAKPMLRNGETGDWVGTFEGHKGAVYCSVFNEDATRLVTGSGDYSSMVWNAVTGDKLHTWSHPKYIKSCDWCGNKIATGCVDGLVRIFDAQAYDANPVCFDSTEKVNQVKATYFIDHTTMVTACENTIMKWDLRDTSLPYLRKEIPGLNFLEYTHSNSIVAAHEKSISFIDTTSLEIKSSFTTSDDIECASLSPNGQNVAAGSKLKAKEFTVDGTELESHRGHHGPIFHIRWAPDGKSFTSGAEDGMARIWPSHDIIETYDNEN
Protein: Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (O44959)
Organism: Caenorhabditis elegans
Function: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its dynamic association with the 40S subunit (By similarity). Plays a role in oogenesis by regulating germ cell proliferation, progression through diplotene and diakinesis stages and oocyte maturation. Regulates germline development probably by regulating the phosphorylation of mpk-1. Involved in larval development.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Protein LTV1 homolog
- RNA-binding protein NOB1
- Ubiquitin-like domain-containing protein
- Small ribosomal subunit protein uS5
- Protein arginine N-methyltransferase 5
- Small ribosomal subunit protein uS11
- Serine/threonine-protein kinase RIO2
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein uS4
Sequence:
MEKVEHLNLNIQNILEDVDIDTASSSSDDEPEQAVVKQEKLEAGEQIEEQYDTDSDYDDDIVEFAEATGDFTKKLNAARLNTIGPNAARNRLTVDVERHADTSEDRKRKRVKDRADRATVEQVLDPRTRLVLFRLLQRGTLLNIDGCISTGKEANVYHATGTDNDLAIKIYKTSILTFKDRERYVTGEFRYRHGYCKSNPRKMVAVWAEKEMRNLARMHEVGLPVPKPHLLKGHVLVMDFLGKDGWPAPLLKNANLSQEDAEPMYVGLVRDMRRLYRECKLVHADLSEFNMLVHDGKLWIIDVSQSVEQDHPHALEFLRMDCNNVNKFFRELGVPVLSVRRLFEVIVDPLMSSKEMETIIEEERVLVNSEDDSLFMNAFIPHKLEHVLHFERDGKLAKEGVEANNPFQNIVSKIDLKGDGFGEEHDDSDDNDDEENGKKSRKKRAEPTEEEIQEKERKIAMHTRNREETAEERKERKAAVKEEKREQRKEKIPKHLKKRAHRQHMK
Protein: Uncharacterized ribonuclease C609.01 (EC 3.1.-.-) (O94525)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Exosome complex component ski6
- Exosome complex component rrp46
- Exosome complex component csl4
- Exosome complex component rrp45
- Exosome complex component rrp43
- Exosome complex component rrp40
- Exosome complex component rrp4
- Exosome complex component rrp42
- Exosome complex component mtr3
- Exosome complex protein C1739.07
Sequence:
MDPHWKRHDSSNIPTQPSPSASPKSNKPSSAQRFGNLPWVAPDVIQSQIEYLQALQMQQSLSESENYLQPNFFPFQSGPFSKSRRENTLLPRLNPLAPIGARQPNPSIPQQFSKPINESGTGTMGPAVGELTSPVMKNRAESIFSPVTESFEAFTQGMQTTPQRAGAGVSTATSHTRRRSSAGTDPFSPVSPSNPNFLTPLKPIDGNQEWQQSPLESPLSMHSLQESLHSVEPESPIFQQAPQIPLSNASQQSYINHSSDGASLPQSSFLNFNSSGKRVSVSAAAQQHKNLFLPYLPQASLPKFIGTGKLLVGTLHINRKNRSDAYVITDVLDEPIFICGSKDRNRTLEGDLVAVELLDVNEIMQTKREKEEKKIRRNLSLSGSSKYSVNSKAKMMSISTPMALGMNRGVLSFERSIEKRKNDYEVTGQSLSFVDDVSLTPDSAPKYAGHVVAVLNRPSGETCSGTLALYRPNSLALKNQSSHRRNSSTSSGETGKGPKIVWFKPSDKRIPLIAISSDQVPPTFFTNNDDFKDKVFLAGIKRWPTTSLHPFGTLYESIGTIGDPKVEYKAILHDFSCHTYDFPESLSHCVKRLPTPIPAEELQKRYNLRDKLTFMIGTRDYALHIDTGSIDGVITLGIHVADVAYYVKQDMPLDDEAANRVSEVQLLQGSVPFLPKKVSEEISLIEGHDCLTISIVVQLDLKSGAVLQCSLGPSVIHPSSFISLESAQANLQTNEALQLVDASAHVLTKLRLKTDKKLDLQSLYCFEFCDGQIPNIQNINMSIFEAFPIACSLQQIEHWVNEKVASHLMSVFPSKVILRKNQRPSDFASLVAVSELTGVNLSASSTPSEIMTEIATTKDKRTKMLLQLTLRRMCNESEYTIGTSNAKDVSHFVFSCPYYTHFCHPTRRYIDICVQRQLREAFDGRPDFSKDYRSLLSITQSCNTLSNFYRNAQEKSLHAYLCQLLHSINLRSGLVKHKAFVLAVDQEYIDIVIYEFGLERRISLDLLPLSNCDFNEQKHELYLSWRTNASFFYASSSLEIDTPCFNDFKKKFLDSNGMCKQICDMMDAQVRDLANAAESQESFYSKARGNDSTSKTAKSSSGNQDISGDGKLHSLRMKEPEVVQTIRPGQEVSVLIFADTSATYSLSLITLQSPLSS
Protein: Nudix hydrolase domain-containing protein (O69640)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDAYRRRLPADVLAMVTAAGAVSAMTSSRRDHREAAVLVLFSGPEAGPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALREANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAETAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVISAVLDVAGWAQPWDTGDIRELDAAMVLIDDESDPR
Protein: Missing-in-metastasis, isoform C (A1Z6S0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDLSLERDSSALGSLFQQIINDMKNTSPLWEDFVAKAGKLHTCLRAAIQAIAAYLDAFQKIADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARKGQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAMQSIALVTKEPSVLPQASEELIHDAKASINLYPESPGGGSGSQGGGCSNSLGSRKSSVCSISSMNSSGSSNSPGHHHYPRSLSQTSNATNQTANVSTWPPHSQDGVDTLPPTADRPHTISTAYEKGHQRPPLTVYTFQNPETIHESGSCLNNGTAAPNGQPLSGQATPATQKSPAASLSRPPLPVRCSSLERPLSAQSNHRQGSGNNLLQRQCPSPIPAHITKELSAAHHAQQQQQQQNQQPQTPPTYVNMSELATMAALKQTNQQQKPSTPPLQQQSSIDSTSSQHSNDSTGSHQLLQQQQQHHQSQQNHHSATATRSHSISSTASSLHSHPSIDSTVACGSLVGQHNHSTSTNTNTTSPSSGSSTPQNHYSPLLTNSPTSTAAGTPSGSSLGPGSGLGFVYQVSSPTPPSSEVLKITEQAAAGQDQGPANSVADETDERSRASVLQKASMFEKAAAAAAVSPPAPMQIASGSPASGGGTRRSEAEQQEMDKSFEDSIQALNNLIGELDSFQREIDEGKVKPPSNIISGSTTSSNNNNTTTSSISSSDNNNLPATSNIEPCAISNQTNSSGCGTDISDTTSDELAGDDMDVRRRDRDRDRDLLGASDSELSRCYVSETSSLTGGLTAGGYENPTFAHFAANANREDAVSLASDSVCLGQPRHAYVDTCSDSGSAVVVIYDHQIPNTPDIEFVKQNSEIVVLRTKDPQPHALQLHEMRELQQLPANLAGSPDSSPDSAGGQAPPTATVAPAKQRLSSFRATSEQQLQLLGRGSPQRGKTPSEQAVQSRPQDQHFPQTQQQDIDGSSPPVELARRQLPPKPTSLSIFNGPVPTAGDRPVVPRKSDFKADLDAKIRRQKQKVKQQLQQQQQQQQQEQQETQQQQQAPQEQQHSPQSPQTRNCNVTNQQAANITASASAFATATASTDPYPNPNHRMPNQNQTATSNHTQCKTPTMALSPSSPRGHLPLSSSSLSSLPLPATTSSPSNARPSMLPASDRPPAHPYVCSNAPANPHHANSISNANAHLKPCITPRPASLSGGAAGGGSTRIGRRSSINQSKPPPPVRRSSSVTPSPNASVGLQQQPQHATLSQQNHQLSSSSEHLPPPPPFMLDAMPQIPSSALKVSETVRALAAMRHQPASPVSLRRMQQQQQQQLQQQQQQQVQQQQPLLQSAHNSPLKEDLTVYYDSYLDLHAYAQALASGQQPGGQQMANQQRFTLQQQHQHLHQPQQPPVYQVDATFRTSSPAAGGGGGGGIYAQPKLVNSMSSFRTSSPSPNGHAHPLPPTQPKANPNLIAQLNARLSGKQQQHQQQQHIEGIYGNQQAPGGESIYMRSGLSMSQPQQQQHFDGKSEQIQLQHQQQHRIYASFGTSSSAMSSAHAANSSTKPSILTPTTSFNALPHFPLSSSTSSLLSKVSSFSNSSSASPPTTAATSGSASSHYQPPQPPNAAVANSKDMAIYSSSFTKNPAAAQSPNMRQAHSHQHHQPPQQQHYTCPPPLEDPPPPPIYAAGASATMPKKMARPPTGQNATHSSAYAAASSTATLPKNMMQQQQRLQHQQQYQQPAGMGIGNGNGHLGQRPQLPLPQQKLRAAQQQHLAEQQHQQQQEQQQHHQQHQQHQQRQPPIPSRHSSVQQKIFVSTNPFIQTTAVKFHSPSASPTCGSPVTGSLASIYATTSRGGHHHQQQQAQQQQHYYRDAAGGNSNGGAAYYNHNAHAHSQAHHPNYATSTNIEKTGSIRAKTKAEFLENLNAKLAKQGMSGRAFAVRNLINSKALPDPRICHESLMDQIKRGATLKRNQKINDRSAPKIH
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A0A0H2UVV3)
Organism: Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYIQNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVAFAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYNRSRERKIVFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPTKKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDVGLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDYQEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAVSDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSGQSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSPSETTAQTP
Protein: Spore wall protein 9 (R0MLT0)
Organism: Nosema bombycis (strain CQ1 / CVCC 102059) (Microsporidian parasite) (Pebrine of silkworm)
Function: Involved in adherence of spores to the host cell surface and in infection efficiency.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25605761}. Spore wall {ECO:0000269|PubMed:18563739, ECO:0000269|PubMed:25605761}. Spore polar tube {ECO:0000269|PubMed:25605761}. Note=Localized to the cytoplasm of sporonts, to the cytoplasm and surface coat of sporoblasts and to the spore wall and polar tube of mature spores. {ECO:0000269|PubMed:25605761}.
Interaction partners:
Sequence:
MSTQPTKTSSTKLRIFKWLFIISTLVAIAIPITRLLMHLYGKIDEKMYARIFMSYRVNSADSFMINGRYKAIKAKAYPTSEERNKFNSIAQEGDKAVLLKYPYPEHFSLEPEWHYTLCDDVFYNLWKIRVNVCEYYKNNKQEDIAGLVTPPKEAKVDRFFRQDPKISDDDYKKLFTGTDENGKGWSSAAVQFIDILLNLINKPEECKLKDGKLNEKFQKDLESLVSQLGYSTEDMKNIANEIPNFFIQFGKAFPTVIHSTVYSRFYYFFLFLTINGNFDFSEVEKTDGMKIEEFNKQTMKVMASVFAQIFAKVYEESYNYEIKDAGFMDKVRAYFSVSDNIDNVKDQTKNINTVKEVLIKNKELLSK
Protein: Type 2A encapsulin shell protein SrpI (Q55032)
Organism: Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2)
Function: Shell component of a type 2A encapsulin nanocompartment. Expression in E.coli generates nanocompartments with an average diameter of 25 nm. They can be disassembled by treatment with 6M guanidine hydrochloride and reassembled with cargo. The nanocompartment is probably involved in sulfur metabolism. Probably allows passage of cysteine into its interior; during growth in light the physiological pH is 8-8.4, about 30-54% of free cysteine (charge -1) would be able to pass through the shell (Probable).
Subcellular location: Encapsulin nanocompartment {ECO:0000269|PubMed:33821786}. Note=Unlike type 1 subfamily encapsulins, the nanocompartment has a raised protuberance around the 5-fold pores. {ECO:0000269|PubMed:33821786}.
Interaction partners:
Sequence:
MTDNAPQLALRDVAARQLANATKTVPQLRTITPRWLVRLLHWTPVEAGIYRVNQVKDASQITVACSERDESELPETFVDYIDNPREYLLSAVNTVVDVHTRISDLYSNPHDQIREQLRLTIEIMKERQESELINSREYGLLNNVAPGQLVHTRNGAPTPDDLDELLIRVWKEPAFFLAHPQAIAAFGRECTRRGVPPATVSLFGSSFITWRGVPLIPSDKVPLENGKTKILLLRVGESRQGVVGLYQPNLPGEQGMGLSVRFMGINRKALASYLVSLYCSLAVLTDDALAVLDNVDVTQYHTYRYN
Protein: Calmodulin, putative (Q386E4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Calmodulin, putative
- Calmodulin-like protein, putative
- Calmodulin
- Glycogen synthase kinase 3
Sequence:
MANAVSEKELEEFREMFDLVDTTRSGRISCTELRRLMETLRLRPTEEELEHMLRSADGNDPDNGIDFDGFVAMMSKRVQTDYTPEQLRTAFKLFETDDMPTGFVSTEVLTHALVSYGTEKLTHDDAIRLLSTLDPDRTGRINYLEFVSLVGGGGVM