wanglab/gogpt-training-data huggingface dataset:
Protein: EH domain-containing protein 1 (AtEHD1) (EC 3.6.5.2) (Q94CF0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in endocytosis positive regulation. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Confers salt tolerance.
Subcellular location: Endosome membrane {ECO:0000269|PubMed:18547399, ECO:0000269|PubMed:23342166}; Peripheral membrane protein {ECO:0000269|PubMed:18547399}. Cell membrane {ECO:0000269|PubMed:18547399}; Peripheral membrane protein {ECO:0000269|PubMed:18547399}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9WVK4}. Cytoplasm.
Interaction partners:
- EH domain-containing protein 2
- Eukaryotic translation initiation factor 3 subunit L
- Histone deacetylase 19
- AP-4 complex subunit sigma
- Ras-related protein RABA1b
- Polycomb group protein VERNALIZATION 2
- Two-component response regulator-like APRR1
- Protein GIGANTEA
Sequence:
MEIESVAAGSCSKENQMIYKEWFEFSDSDGDGRITGNDAIKFFTMSNLPRPELKQIWAIADSKRQGYLGFKEFIVAMQLVSLAQTGHEISHEVLISDVDFKNINPPTMEGLGVLMAKKKHSSKSSDPNMNGSPAADTSLTAHWFSSKSSKKISLSSVTSIVDGLKRLYIQKLKPLEVAYRFNDFVSPLLTNSDFDAKPMVMLLGQYSTGKTTFIKHLLKSTYPGAHIGPEPTTDRFVVVMSGPDERSIPGNTVAVQADMPFSGLTTFGTAFLSKFECSQMPHPLLEHVTFVDTPGVLSGEKQRTQRAYDFTGVTSWFASKCDLILLLFDPHKLDVSDEFKRVISSLRGHDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVLNTPEVSRVYIGSFSDKPINEAATGPIGRELFEKEQDDLLADLKDIPKKACDRRINEFVKRARAAKIHAYIISHLKKEMPAIMGKAKAQQKLIDNLEDEFGKVQREHHLPKGDFPNVDHFREVLSGYNIDKFEKLKPKMLQTVDDMLGYDIPELLKNFKNPYD
Protein: Male accessory gland protein (Serpin 75F) (Q3HKQ3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GH21475p
- IP10416p
- Serpin 77Bb
- MIP05602p
- Serine protease inhibitor 28Dc
- Serpin 85F
- Serpin 42Db, isoform C
- Serpin 100A
- Serine protease inhibitor 27A
- Serine protease inhibitor 77Ba
Sequence:
MFKRVLICFLIFLLKHSYAYNFEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQLTGLNQEEIISLFKEAREKVAQEQFTMGNRIYLSPDYNASPNITQLSENLGVEVKNMTFSGDQSAASEIKKWLNKWIGKAGGNLFGKNDISQTTQIVAVQGMSYSCVWKNRETALTNRTFTLLRQNKKPFVYTTQMMYTEAPMDFFNNDQVRGVMVPFKNSDMGMLVLLPRPRYSTQQILYSLDTILKIKLRRSKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNAANFKQYNSFDADQNRVLMTIDVGDDFDDRVVYVNRGFVFVVKDKSTIYMIGRMDAV
Protein: Early growth response protein (Q5ZLU9)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU363046}.
Interaction partners:
Sequence:
MAAAKAEMQLLPSLQISDPFGVFPHSPPAMDGHYPKLEEMMLLSGGGQQFLAPSGAPESAGFGAAGEPSEQHFEHLAADTFPEISLNNEKTMPETSYPNQTTRLPPITYTGRFSLEPAPNGSNTLWPEPLFSLVSGLVSMANAPPTSTPSSSSPSSSQSTPLSCSVQASENSPIYSAAPTFPTSSSDIFPEPQTQPFPNPSGVPIQYPPPAYPTAKTNFQVPMIPDYLFPQQQSELNLISADQKPFSALETRAQQPSLTPLSTIKAFATQTGSQELKTLNANYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKVEKAASVSATSSSVAAYSSSVATSYSSSIATTYPSPVRTVYSSPASSSYPSPAHTTFPSPSIATTYSSGTATFQTQVATSFPSPGVTNNFSSQVTSALSDMTSTFSPRTIEIC
Protein: Synapse-associated protein of 47 kDa (Q960T2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFSGLTNQFTSLVGAVKGGAGDEDVPAPTGDAPAAAPAASTSVEATASSAVDPEAAAAAGGEGLEGEEAGKRLPKSASLVDSLVSEATGWLGSAKGWLGNASIPSMPAMPSMPSMPAMPAMPSIPSIPGLRKGAGADGAEGAEGAVAGEGGAAASGAVSGGEDDDKSRYISATEGADSHPASGGGTPTGDEGQIGQGKGDEVKITTKVTQQAKHFGSFLSSAISKAGSKIKETVKDNTILDSFNKEQEAFIKGQGGVGNGAAPWIGHANEAKIKEEILGLSQDRRNFVRAPPAGVDFEFSYDTAYPTAIAIMAEDKALETMRFELVPKIITEENFWRNYFYRVSLIIQAAELGTLGADGVGQASSGEDANEVATKEKKSKTAEPAKGDSSVKAIAEQPKAVIEPEAQECDVQAAKSKAKAKAQAGKELGQKISESEFVSDDFQASSESDLAEIQDGMRKLGIDSMTQQALAATDEEQWEKDLEAELKDYEVVDEGGTGGDGGGGRRKGRKAGEDDTEADEDEPTISNLRTRSTNNDWEEYADLIEDTDDLK
Protein: ABC transporter B family member 17 (ABC transporter ABCB.17) (AtABCB17) (P-glycoprotein 17) (Putative multidrug resistance protein 19) (Q9LSJ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
- GDSL esterase/lipase 7
Sequence:
MGKEDEKESGRDKMKSFGSIRSIFMHADGVDWILMALGLIGAVGDGFITPVVVFIFNTLLNNLGTSSSNNKTFMQTISKNVVALLYVACGSWVICFLEGYCWTRTGERQAARMREKYLRAVLRQDVGYFDLHVTSTSDVITSISSDSLVIQDFLSEKLPNFLMNASAFVASYIVSFILMWRLTIVGFPFIILLLVPGLMYGRALVSISRKIHEQYNEAGSIAEQAISSVRTVYAFGSENKMIGKFSTALRGSVKLGLRQGLAKGITIGSNGVTHAIWAFLTWYGSRLVMNHGSKGGTVFVVISCITYGGVSLGQSLSNLKYFSEAFVAWERILEVIKRVPDIDSNKKEGQILERMKGEVEFNHVKFTYLSRPETTIFDDLCLKIPAGKTVALVGGSGSGKSTVISLLQRFYDPIAGEILIDGVSIDKLQVNWLRSQMGLVSQEPVLFATSITENILFGKEDASLDEVVEAAKASNAHTFISQFPLGYKTQVGERGVQMSGGQKQRIAIARAIIKSPKILLLDEATSALDSESERVVQESLDNASIGRTTIVIAHRLSTIRNADVICVIHNGQIVETGSHEELLKRIDGQYTSLVSLQQMENEESNVNINVSVTKDQVMSLSKDFKYSQHNSIGSTSSSIVTNVSDLIPNDNQPLVPSFTRLMVMNRPEWKHALYGCLSAALVGVLQPVSAYSAGSVISVFFLTSHDQIKEKTRIYVLLFVGLAIFSFLVNISQHYGFAYMGEYLTKRIREQMLSKILTFEVNWFDIDDNSSGAICSRLAKDANVVRSMVGDRMSLLVQTISAVIIACIIGLVIAWRLAIVMISVQPLIVVCFYTQRVLLKSLSEKASKAQDESSKLAAEAVSNIRTITAFSSQERIIKLLKKVQEGPRRESVHRSWLAGIVLGTSRSLITCTSALNFWYGGRLIADGKIVSKAFFEIFLIFVTTGRVIADAGTMTTDLARGLDAVGSVFAVLDRCTTIEPKNPDGYVAEKIKGQITFLNVDFAYPTRPDVVIFENFSIEIDEGKSTAIVGTSGSGKSTIIGLIERFYDPLKGTVKIDGRDIRSYHLRSLRKYISLVSQEPMLFAGTIRENIMYGGTSDKIDESEIIEAAKAANAHDFITSLSNGYDTNCGDKGVQLSGGQKQRIAIARAVLKNPSVLLLDEATSALDSKSERVVQDALERVMVGRTSIMIAHRLSTIQNCDMIVVLGKGKIVESGTHSSLLEKGPTGTYFSLAGIQRTLC
Protein: Laccase-13 (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase 13) (Diphenol oxidase 13) (Urishiol oxidase 13) (Q9LYQ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Lignin degradation and detoxification of lignin-derived products.
Subcellular location: Secreted, extracellular space, apoplast {ECO:0000305}.
Interaction partners:
- Phenylalanine ammonia-lyase 1
- Phenylalanine ammonia-lyase 2
- Phenylalanine ammonia-lyase 4
- Phenylalanine ammonia-lyase 3
- Cinnamoyl-CoA reductase 1
- Cinnamoyl-CoA reductase 2
- Basic blue protein
- Putative caffeoyl-CoA O-methyltransferase At1g67980
- Probable caffeoyl-CoA O-methyltransferase At4g26220
- Trans-cinnamate 4-monooxygenase
Sequence:
MEQLRPFFLLLAIFVASLVNAEVHFHEFVIQETPVKRLCRVHNSITVNGQFPGPTLEVRNGDSLVITAINKARYNISLHWHGIRQMRNPWADGPEYITQCPIQPGGSYTYRFTMEDQEGTLWWHAHSRWLRATVYGALIIRPPLSSPHYPFPVIPKREITLLLGEWWDRNPMDVLNLAQFTGAAPNISDAFTINGQPGDLYRCSSQETLRFLVGSGEIVLLRVINSALNQELFFGVANHKLTVVAADASYTKPFSTNVIMLGPGQTTDVLLTADQPPAHYYMAAHAYNSANAAFDNTTTTAILKYKDASCVTLQAKSQARAIPAQLPGFNDTATAAAFTAQMKSPSKVKVPLEIDENLFFTVGLGLFNCPTPNTQRCQGPNGTRFTASINNVSFVFPKQNSIMQAYYQGTPTGVFTTDFPPTPPVTFDYTGNVSRGLWQPTRGTKAYKLKFNSQVQIILQDTSIVTTENHPMHLHGYEFYVVGTGVGNFNPNTDTSSFNLIDPPRRNTIGTPPGGWVAIRFVANNPGAWLMHCHIDSHIFWGLAMVFLVENGEGHLQSVQSPPLDLPQC
Protein: Protein tost-1 (Twenty one u antagonist 1) (Q18490)
Organism: Caenorhabditis elegans
Function: Component of the tost-1 variant of the PETISCO complex which plays an essential role in embryogenesis. Within the complex acts as an adapter which binds to the complex via erh-2. Does not seem to play a role in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs). May inhibit 21U-RNA accumulation. Required for chromosome segregation and cell division in early embryos.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31216475}. Nucleus {ECO:0000269|PubMed:31216475}. Note=During early embryogenesis, localizes to the nucleus at prophase of cell division, and remains in the cytosol at interphase in 2- and 4-cell embryos (PubMed:31216475). Mainly localizes to the germline cytoplasm (PubMed:31216475). {ECO:0000269|PubMed:31216475}.
Interaction partners:
- Enhancer of rudimentary homolog 2
- Embryonic developmental protein tofu-6
- Protein pid-3
- Enhancer of rudimentary homolog
- Protein pid-1
- Eukaryotic translation initiation factor 4E-3
- Schlafen-like protein 1
- K Homology domain-containing protein
- Schlafen-like protein 2
- piRNA biogenesis factor prde-1
Sequence:
MTTAIQYQVIPLADREHSNKVASILENKYKTATNKRITLNERFGVLEKGYTIQATEPETVKNDSDVFFVVHDRNLNSKKEFVENYLAKNPIVNSPEKVFEEEDKENAPTKKAVLKPSSTDEKKLTSSDIYIQEITRSILQSV
Protein: Coatomer subunit beta' (F4J1E5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004347, ECO:0000256|PIRNR:PIRNR005567}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004347, ECO:0000256|PIRNR:PIRNR005567}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004347, ECO:0000256|PIRNR:PIRNR005567}. Golgi apparatus membrane {ECO:0000256|PIRNR:PIRNR005567}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR005567}; Cytoplasmic side {ECO:0000256|PIRNR:PIRNR005567}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000256|PIRNR:PIRNR005567}.
Interaction partners:
Sequence:
MPLRLDIKRKFAQRSERVKSVDLHPTEPWILASLYSGTVCIWNYQTQTITKSFEVTELPVRSAKFIPRKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWENGWACTQIFEGHSHYVMQVVFNPKDTNTFASASLDRTIKIWNLGSPDPNFTLDAHQKGVNCVDYFTGGDKPYLITGSDDHTAKVWDYQTKSCVQTLDGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENTLNYGLERVWAIGYIKSSRRVVIGYDEGTIMVKLGREIPVASMDSSGKIIWAKHNEIQTANIKSIGAGYELSSLYLRLLMEKDFPCLLKSWGPVIFIHNYSNSQSLKHNPNGRFVVVCGDGEYIIYTALAWRNRSFGSGLEFVWSSEGECAVRESSSKIKIFSKNFQERKSIRPTFSAEKIFGGTLLAMCSNDFICFYDWAECRLIQQIDVTVKNLYWAESGDLVAIASDTSFYILKYNRELVSSHFDSGRPTDEEGVEDAFEVLHENDERVRTGIWVGDCFIYNNSSWKLNYCVGGEVTTMYHLDRPMYLLGYIANQSRVYLVDKEFNVIGYTLLLSLIEYKTLVMRGDLDRANQILPTIPKEQHNNVAHFLESRGMIEDALEIATDPDYKFDLAIQLGRLEIAKEIAEEVQSESKWKQLGELAMSSGKLQLAEDCMKYAMDLSGLLLLYSSLGDAEGVSKLACLAKEQGKNNVAFLCLFTLGRLEDCLQLLVESNRIPEAALMARSYLPSKVSEIVALWREDLSKVNPKAAESLADPEEYSNLFEDWQVALSVEANTAETRGVYTAAENYPSHADKPSITLVEAFRNLQVEAEESLENGNIDHEVAEENGHVENEGDEEEQQEEEVNEEEGVVDADSTDGAVLVNGSEGEEEWGTNNKGNPSA
Protein: Chitinase 6, isoform G (EC 3.2.1.-, EC 3.2.1.14) (M9NEC2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLPFRRGAAWQTLFLLCALAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYLCTHLVYAFGGFTKDNQMKPFDKYQDIEQGGYAKFTGLKTYNKQLKTMIAIGGWNEASSRFSPLVASNERRQQFIKNILKFLRQNHFDGIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREAEKTGRTRLLLTMAVPAGIEYIDKGYDVPKLNKYLDWFNVLTYDFHSSHEPSVNHHAPLYSLEEDSEYNYDAELNIDYSIKYYLKAGADRDKLVLGIPTYGRSYTLINEESTELGAPAEGPGEQGDATREKGYLAYYEICQTLKDDPEWTVVQPNANVMGPYAYRRNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRGTCNGKPYPLIEAAKEAMVEALGLGINEVAKPSGPQKPSRSRSRDNASNRNRLNGKTEAPLSSRRPSATRRPAVSSTQAPPPSTTFKLTEAEGSSLYIGGRASTTPPPPTTPDPGSDFKCEEEGFFQHPRDCKKYYWCLDSGPSGLGIVAHMFTCPSGLYFNPAADSCDFARNVPCKTKKSTTAAPVTSTTPATTTVRSNRVTAAPTSRPVYPRTTTTTSTTTTTTTTPSTVDEDLEYEEDTDELSPSKSTDAEEDPQVIKELIDLIRKVGGVEQLEKHLLRNKDGSITLKENSATGAATTPSTISKSLYDRVLSRPGTLNSFSRNRFKISEASETSTEPTTSSSSSRGSSTLTSNTNSKYSSVLRGNSRQGPQNEGIEKLAEFDGFLKERKQYVTINRHRSASQGDEEEHADQQEEEENLAEVETTTRRPLSSITPSYTSLRRSRPTTVAPPAEESHEEAEQQTQTQVKSYATLSRTRGRTTSSPEVTEAAPSSTTNRYKYFERTRPTKSATAEDSEDPTEDEEEEYEDEQKDIVTVQSKQSTNTRKYASIGRRTTTTTTATPETTTTTTTTTAGTETAKASTTTNNNNNNNSHYNSSNNNNNVKLNNQLPTEENITTTPSTTAQSETTTTTNETTEPNESTSTTTTSITNNLHTTTTTPTPIVASTVPTTTANGISSDSLLATELSEASPTHLSPSPDSETSTPTTTSTTTTEQPELDTTTTTPKTTTTTTTGNNELNDVNNVDEDSELRQPTTGSVSRRPVLSVRRRIINSPTSAAVETTTQQPAAEPPTTSKYSRLRSRPSATATAAAAAATTTTAAATTAFPAATSAPGGRTTSNIYLSKLKAKSGAAAAAAASGEAATLTPATSNISSSSNDITQKQHKFQPASFALRRQFQTRRLTTFAPAANGDESATEVPRTQNPLFKRRLTLISTTPPSARTTNPPVSGLETTTTLYLNDDDEDQVAKSSIHTSRFNQIPEQVRPREEYDLALPAQPLKSTSTTVSTTANAPLPVIGQGIRRQLIPRPRRPQSTTSTPPTTTTSGSTLRSTTSAGHSAPPLSRRQQSRRRPHKYIEVYSRPPAKTAVISATSSSQFLDEGFPVVHSQVAQRRRSGSILPTKNDPKVIVHGHGIIECRAQGNFPHPLNCRKFISCARFEETGGIVGWEYTCPKGLTYDGVGGMCTWSPSDQPCRD
Protein: Putative pentatricopeptide repeat-containing protein At3g15200 (Q9LIL5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGGKNKIEILFQLQSALSRRRISSLVDFRRVFPPETPNHKNNITLSRFHFLGTHFLHSLGAPDKFPNRFNDDKDKQSALDVHNIIKHHRGSSPEKIKRILDKCGIDLTEELVLEVVNRNRSDWKPAYILSQLVVKQSVHLSSSMLYNEILDVLGKMRRFEEFHQVFDEMSKRDGFVNEKTYEVLLNRYAAAHKVDEAVGVFERRKEFGIDDDLVAFHGLLMWLCRYKHVEFAETLFCSRRREFGCDIKAMNMILNGWCVLGNVHEAKRFWKDIIASKCRPDVVSYGTMINALTKKGKLGKAMELYRAMWDTRRNPDVKICNNVIDALCFKKRIPEALEVFREISEKGPDPNVVTYNSLLKHLCKIRRTEKVWELVEEMELKGGSCSPNDVTFSYLLKYSQRSKDVDIVLERMAKNKCEMTSDLYNLMFRLYVQWDKEEKVREIWSEMERSGLGPDQRTYTIRIHGLHTKGKIGEALSYFQEMMSKGMVPEPRTEMLLNQNKTKPRVEDKMLRSNLTSEESESD
Protein: Spt5 C-terminal domain-containing protein (Q383G9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSLDPRSCDAICEELHAESCICDGAGILNLCRQVKELRVGIRRLLTEDIPTLGDIITEFQEPHLREFRDFHRGARRDNVVRTPTDIVFATTSLLRCCNELSSNVTRGFNRLANKETVKLNTHAIGYAPIFSREKYSSYPPATVETEKNENRTKDKKLNSNHCAAPQVKAGGEKEGKANPQARHETSRSLVSQKEILTSRLTTVDKYPAFGQAITEDKPLAFGQGATADKPPAFGQGVTADKPPAFGQGAAAGTTPAFGQGVTAGTTPAFGQGVTADKPPAFGQGAAADKPPAFGQGVNADKPPAFGQGVNADKPPAFGQGVTADKPPAFGQGVTADKPPAFGQGAAADKPLAFGQGATADKPPAFGQGVTADKPPAFGQGAAADKPPAFGQGVTAGTTPAFGQGVTADKPPAFGQGVNADKPPAFGQGVNAGTTPAFGQGVTAGTTPAFGQGVTAGTTPAFGQGAAADKPPAFGQGVNADKPPAFGQGVTAGTTPAFGQGVNADKPPAFGQGVTAGTTPAFGQGAAADKTPAFGQGVTADKPPAFGQGVTAGTTPAFGQGVTAGTTPAFGQGVTADKPPAFGQGVNADKPPAFGQGVTAGTTPAFGQGAAAGTTPAFGQGVNADKPPAFGQGVTADKPPAFGQGAAAGTTPAFGQGVNADKPPAFGQGAAAGTTPAFGQGVNADKPPAFGQGAAADKPPAFGQGAAADKPPAFGQGAAAGTTPAFGQGVNADKPPAFGQGAAAGTTPAFGQGVTADKTPAFGQGVAADKPPAFGQGVAADKPPAFGQGAAANKASVFGQGVTAGTTPAFGQGVAADKPPAFGQGVAADKPPAFGQGAAANKASAFGQGVTAGTTPAFGQGVAADKPPVFGQGVAADKPPAFGQGAAANKASVFGQGVTAGTTPAFGQGVAADKPPVFGQGVTADKPPAFGQGVTADKPPAFGQGVAADKPPVFGQGVAADKPPAFGQGAAANKASAFGQGVTAGTTPAFGQGVAADKPPAFGQGAAAGTTPAFGQGVTAGTTPAFGQGVTAGTTPAFGQGAAANKASVFGQGVTAGTTPAFGQGVTAGTTPAFGQGATAGTTPAFGQGVTAGTTPAFGQGVTAGTTPAFGQGAAANKASVFGQGVAADKPPAFGQGVAADKPPAFGQGAAANKASVFGQGAAANKASVFGQGVAADKPPAFGQGAAANKASVFGQGAAAGTTPAFGQGAAADKPPAFGQGAAAGTTPAFGQGVTAGTTPAFGQGAAANKASVFGQGAAAGTTPAFGQGAAAGTTPAFGQGAAAGTTPAFGQGAAAGTTPAFGQGAAAGTTPAFGQGVTAGTTPAFGQGAAAGTTPAFGQGAAANKASVFGQGVTAGTTPAFGQGAGGCVSNSVFGTTPASGGCELGTICGFGSDPSGVKSLRVNLGANCGVGTPSVFGVPGHVSSPQVAPFGSAATSHVFQSSSFSSIAGNYKATPDFKSVFSQ
Protein: Sulfocarbamoylase-1 (EC 3.1.1.-) (Sulfocarbamoylase I) (P86101)
Organism: Megangulus venulosus (Japanese bivalve) (Tellina venulosa)
Function: Hydrolysis of sulfocarbamoyl esters of paralytic shellfish toxins. Does not hydrolyze the carbamoyl esters of paralytic shellfish toxins. Ester hydrolysis is significantly affected by the stereochemistry of sulfate esters at C-11 of the substrate toxin.
Interaction partners:
Sequence:
TTEEVPLNPEPRTECDSDNCAAGERPYAPNIAIENGDTIIAIGVVADVMFVIDXNCPLYCNFCIVADVMFVIDLVYEVGSFEALQQAIDNIMFT
Protein: GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1) (P83337)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP-fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that can then extend the fucosylation on the NOTCH EGF repeats. This extended fucosylation is required for optimal ligand binding and canonical NOTCH signaling induced by DELTA1 or JAGGED1 (By similarity). Fucosylates AGRN and determines its ability to cluster acetylcholine receptors (AChRs) (By similarity).
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q6EV70}.
Interaction partners:
- GDP-fucose protein O-fucosyltransferase 2
- Coagulation factor X
- Alpha-
- EGF domain-specific O-linked N-acetylglucosamine transferase
- KTEL motif-containing protein 1
Sequence:
MGAAAWAPPHLLLRVSLLLLLLLPLRGRLAGSWDLAGYLLYCPCMGRFGNQADHFLGSLAFAKLLNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEEFMEKLAPIHWPPEKRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYKEQWIQRFPPEEHPVLALPGAPAQFPVLEEHRALQKYMVWSDEMVKTGEAQISTHLIRPYVGIHLRIGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTATPLTMTMCLPDLNEIQRAVKLWVRALNARSIYIATDSESYVPEIQQLFKEKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTAFVKRERDLHGRQSSFFGMDRPSQPRDEF
Protein: Non-functional pseudokinase ZRK6 (Q9SVZ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F12K21.25
- Protein kinase superfamily protein
- Serine/threonine-protein kinase ATG1a
- Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform
- Probable ethanolamine kinase
- non-specific serine/threonine protein kinase
- Probable protein phosphatase 2C 36
Sequence:
MDWLRTKRIRAKKRKRNVKENGEVVLKELIECCDGKCNPIKNFSYDQIIKATNNFCQSNRASRIDVYYRCYKGMLDDRPVLIKKGKYTLDMKEICRDIAISSMVSGHKNFLKLLGCCLEFTPPVLVFEYAEVITLGPLLTSHPGYLRRIKIAREVANALTYLHTAFSRVFIHSNLDPFTIFLDGNGVAKLGNFCNCITIPEGETFVHDDTLQKYHELRHNTLKGTHGLGVCNLPVIDPDYKSTGKVTTKTDMHSFGGFMLALVQIREVDDELSLSSDMLRALADLFIKPYDDVRYVHFPLHHHVSKILRKFGYAEVVDSDMSEVAAWPIKAFLRLALRCIGCKLGDPLSSMIQVTKELRLIEKSAYYPSNNRSQMSSI
Protein: XPA, DNA damage recognition and repair factor (D4A981)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- DNA excision repair protein ERCC-1
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- DNA repair endonuclease XPF
- General transcription and DNA repair factor IIH helicase subunit XPD
- DNA excision repair protein ERCC-5
- DNA excision repair protein ERCC-6
- General transcription factor IIH subunit 3
- DNA damage-binding protein 2
- General transcription factor IIH subunit 1
- UV excision repair protein RAD23 homolog B
Sequence:
MATAEEKRTSPEPAAAEKPAELPAAVRASVERKRQRALMLRQARLAARPYPAAAATGGVTSIKAAPKVIDTKGGFILEEEEEEKHKIGDVVHEPGPVMEFDYTICEECGKEFMDSYLMNHFDLPTCDSCRDADDKHKLITKTEAKQEYLLKDCDLEKREPALRFIVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKVGFYDAMKILLYDKPLY
Protein: Optomotor-blind protein (Lethal(1)optomotor-blind) (L(1)omb) (Protein bifid) (Q24432)
Organism: Drosophila melanogaster (Fruit fly)
Function: Essential protein that may function as a transcription regulator. Vital for pupal development. Required for proper development of the optic lobes and wings, and abdominal pigmentation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Protein decapentaplegic
- FI23031p1
- Protein wingless
- Brinker
- Dpp target protein
- receptor protein serine/threonine kinase
- Protein hedgehog
- Homeotic protein spalt-major
Sequence:
MRYDVQELLLHQSAEDPFARFANGMAYHPFLQLTQRPTDFSVSSLLTAGSNNNNSGNTNSGNNNSNSNNNTNSNTNNTNNLVAVSPTGGGAQLSPQSNHSSSNTTTTSNTNNSSSNNNNNNSTHNNNNNHTNNNNNNNNNTSQKQGHHLSTTEEPPSPAGTPPPTIVGLPPIPPPNNNSSSSSSNNSASAAAHPSHHPTAAHHSPSTGAAAPPAGPTGLPPPTPPHHLQQQQQQQQHPAPPPPPYFPAAALAALAGSPAGPHPGLYPGGGLRFPPHHPGAHPHAHHLGSAYTTAEDVVLASAVAHQLHPAMRPLRALQPEDDGVVDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVGPPQSPLLPLSHSLQQMHAHQHSAALAAWFNHLAGAGAGASEHAAAAAANASAEDALRRRLQADADVERDGSDSSCSESVGGSTGGAFRPTSTGSPKEAVGAAAAAAAAGLNPGGGSYPSPNISVGPPIHPSPHLLPYLYPHGLYPPPHLGLLHNPAAAAAMSPAGLNPGLLFNAQLALAAQHPALFGHAYAAAGHTPVSPLQGLKSHRFSPYSLPGSLGSAFDAVTPGSNANRSGDPPGGGGGGLGGGVVENGPRSLSSSPRPRPASHSPPTRPISMSPTTPPSLMKQPRGGGAGAGVAQSQHSPSELKSMEKMVNGLEVQHNGSAAAAAAALQLAEEAAQHHHHTQAHHQQQQHQSHHQQQHHQQPAQPHPHHQTHLHSHHGATTGGTDQ
Protein: Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 1) (P38710)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Inositol-3-phosphate synthase
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Inositol monophosphatase 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
- Histidine biosynthesis trifunctional protein
- Imidazoleglycerol-phosphate dehydratase
- Histidinol-phosphate aminotransferase
- Glucose-6-phosphate isomerase
Sequence:
MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGETVITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDEQTKYITDFWNCVDGHLKYD
Protein: Multicopper oxidase LPR1 (EC 1.-.-.-) (Protein LOW PHOSPHATE ROOT 1) (F4I4K5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Multicopper oxidase that may be involved in copper homeostasis and oxidative stress response, and that is necessary for root growth inhibition by low phosphate conditions. Functions together with LPR2 and PDR2 in a common pathway that adjusts root meristem activity to phosphate availability. Oxidizes the substrate 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulphonate) in vitro.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:19666499}; Peripheral membrane protein {ECO:0000305|PubMed:19666499}. Note=Associates with PDR2 at the ER membrane. {ECO:0000305|PubMed:19666499}.
Interaction partners:
- Probable manganese-transporting ATPase PDR2
- Glucan endo-1,3-beta-glucosidase 12
- Glucan endo-1,3-beta-glucosidase 2
- AP2-like ethylene-responsive transcription factor At1g79700
- glucan endo-1,3-beta-D-glucosidase
- Potassium transporter 10
- Uncharacterized protein T21H19_30
- Glucan endo-1,3-beta-glucosidase 3
- DNA cross-link repair protein SNM1
- Glucan endo-1,3-beta-glucosidase 6
Sequence:
MESLLCRRRIKRVMVLIIALTWLRSTCGELEDQLFEVGKLKMFVDDLPDMPRLYGFNSVHGIIKPASLQIGMFSTKWKFHRDLPATPVFAYGTSRSKATVPGPTIETVYGVDTYVTWRNHLPKSHILPWDPTISPATPKHGGIPTVVHLHGGIHEPTSDGNADAWFTAGFRETGPKWTKTTLHYENKQQPGNMWYHDHAMGLTRVNLLAGLVGAYILRHHAVESPFQLPTGDEFDRPLIIFDRSFRKDGSIYMNATGNNPSIHPQWQPEYFGDVIIVNGKAWPRLNVRRRKYRFRIINASNARFFKFFFSNGLDFIVVGSDSAYLSKPVMTKSILLSPSEIVDVVVDFYKSPSRTVVLANDAPYPYPSGDPVNEENGKVMKFIINNESEDDTCTIPKKLINYPNADVSNAVLTRYISMYEYVSNSDEPTHLLVNGLPYEAPVTETPKSGTTEVWEVINLTEDNHPLHIHLGLFKVVEQTALLAAGLEEFKECMTKQNDAVKCQISKYARGKKTAVTAHERGWKNVFKMMPGHVTRILVRFSYIHTNASYPFDPTQEPGYVYHCHILDHEDNMMMRPLKVII
Protein: Ferritin (Q8TD27)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasmic vesicle, autophagosome {ECO:0000256|ARBA:ARBA00004419}.
Interaction partners:
Sequence:
MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLEFPSPISPSPSCWHHYTTNRPQPQHHLLRPRRRKRPHSIPTPILIFRSP
Protein: Putative transcription factor PHD1 (P36093)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Putative transcription factor that functions in pseudohyphal growth.
Subcellular location: Nucleus.
Interaction partners:
- Flocculation protein FLO1
- Protein STE12
- Ty transcription activator TEC1
- Protein MSN1
- AP-1-like transcription factor YAP6
- rRNA-processing protein EFG1
- Transcriptional regulator NRG1
- Protein SOK2
- Flocculation protein FLO11
- Transcription factor SKN7
Sequence:
MYHVPEMRLHYPLVNTQSNAAITPTRSYDNTLPSFNELSHQSTINLPFVQRETPNAYANVAQLATSPTQAKSGYYCRYYAVPFPTYPQQPQSPYQQAVLPYATIPNSNFQPSSFPVMAVMPPEVQFDGSFLNTLHPHTELPPIIQNTNDTSVARPNNLKSIAAASPTVTATTRTPGVSSTSVLKPRVITTMWEDENTICYQVEANGISVVRRADNNMINGTKLLNVTKMTRGRRDGILRSEKVREVVKIGSMHLKGVWIPFERAYILAQREQILDHLYPLFVKDIESIVDARKPSNKASLTPKSSPAPIKQEPSDNKHEIATEIKPKSIDALSNGASTQGAGELPHLKINHIDTEAQTSRAKNELS
Protein: Proton-activated chloride channel (PAC) (hPAC) (Acid-sensitive outwardly-rectifying anion channel) (ASOR) (Proton-activated outwardly rectifying anion channel) (PAORAC) (Transmembrane protein 206) (hTMEM206) (Q9H813)
Organism: Homo sapiens (Human)
Function: Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH. Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling.
Subcellular location: Cell membrane {ECO:0000269|PubMed:31023925, ECO:0000269|PubMed:31318332}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Trans-2,3-enoyl-CoA reductase-like
- Asialoglycoprotein receptor 1
Sequence:
MIRQERSTSYQELSEELVQVVENSELADEQDKETVRVQGPGILPGLDSESASSSIRFSKACLKNVFSVLLIFIYLLLMAVAVFLVYRTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLTSPGQPGDMNCTTQRINYTDPFSNQTVKSALIVQGPREVKKRELVFLQFRLNKSSEDFSAIDYLLFSSFQEFLQSPNRVGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAKKSAQLFFVVFEWKDPFIQKVQDIVTANPWNTIALLCGAFLALFKAAEFAKLSIKWMIKIRKRYLKRRGQATSHIS