wanglab/gogpt-training-data huggingface dataset:
Protein: Filamin B (A0A8I6GK95)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIESTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNSVELLVEDRGNQVYRCVYKPLQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELAVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKTGCTINNPAEFIVDPKDAGNAPLKILAQDGEGQPIDIQMKSRMDGTYVCSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASEEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPVPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGSYAVTYVPLTAGMYTLTMKYGGELVPQFPTWVKVEPTVDTSGIKAFGPGIEGKDVFREATTDFTVDARPLTQVGGDHIKAHIANPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDAPIPNSPFKVAVNEGCQPSRVHAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDTSKAGLAPLEVRVMGPRGLVEPVDVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGQVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEAGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLISVKYGGPNHISRSPFKAKVTGQRLVTPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKEKGDYVLAVKWGEEHIPGSPFHVTVP
Protein: TBC1 domain family, member 5 (B9A6K1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWEELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIKEIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDDSSKDSGFTIVSPLDI
Protein: Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A) (Q17QL5)
Organism: Bos taurus (Bovine)
Function: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF). Can also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q9NV96}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus {ECO:0000269|PubMed:21454556}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:Q9NV96}. Apical cell membrane {ECO:0000250|UniProtKB:Q9NV96}. Photoreceptor inner segment {ECO:0000269|PubMed:21454556}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:21454556}.
Interaction partners:
- Probable phospholipid-transporting ATPase IA
- Phospholipid-transporting ATPase IB
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
- Phospholipid-transporting ATPase
Sequence:
MAMNYNAKDEVDGGPPCPPGGTAKTRRPDNTAFKQQRLPAWQPILTAGTVLPTFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTDPSSPCNKCLSPNVTPCVCTINFTLEQSFEGNVFMYYGLSNFYQNHRRYVKSRDDGQLNGDPSALLNPSKECEPYRRNEDKPIAPCGAIANSMFNDTLELFQVGNASDLTPIPLKKKGIAWWTDKNVKFRNPPGTDPLEERFKGTTKPVNWVKPVYMLDSDEDNNGFINEDFIVWMRTAALPTFRKLYRLIERKNDLHPTLPAGRYYLNITYNYPVHSFDGRKRMILSTISWMGGKNPFLGIAYITIGSISFLLGVVLLVINHKYRNSSNTADITI
Protein: Small ubiquitin-related modifier (SUMO) (O97102)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU361190}.
Interaction partners:
- GH15225p
- Dorsal interacting protein 4
- Activator of SUMO 1
- Suppressor of variegation 2-10, isoform I
- SUMO-activating enzyme subunit
- E3 SUMO-protein ligase RanBP2
- Ubiquitin-like protein NEDD8
- Ubiquitin-like protease family profile domain-containing protein
- Ran GTPase-activating protein
- Degringolade, isoform A
Sequence:
MSDEKKGGETEHINLKVLGQDNAVVQFKIKKHTPLRKLMNAYCDRAGLSMQVVRFRFDGQPINENDTPTSLEMEEGDTIEVYQQQTGGAP
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q38BA7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Tyrosine phosphatase, putative
- Cell cycle associated protein MOB1, putative
- Cell cycle associated protein MOB1, putative
- BTB domain-containing protein
Sequence:
MCLLIIEHLFYSPCTVTTVLSLKLFGGGEKTGKMSDVPKSQVGTDAKVAVAKKYTGEYYVKGMVGDKKSFAIEHSRGRQKKHTVNEFCVGDAIGRGAFAEVFQCWRPEEPHIVYAMKKIRKDLIVKRKQSLNVHTERDLLSDAKLRQKRVSCPWITDLVVAFQDQDFLYIVTEYCSGGDLISWLIRYDVFPEETARFYFVELVLALNALHKMGYVHRDVKPDNVLIDREGHVKLADFGLSKRDPDQAESTSVADDSYLTEDVTVDDDVKKRFRDKKERKVMFFSTVGSPAYIAPEVLIGRGYDYSCDWWSAGVILYEMIFGYPPFFNDNNTATAKKIIQFKEHLEFPKDQTTVSKEAIDLISHLIADSKERYGFEEIIRHPFCKGVPLTDSIRNEKAPFSVELNSPRDLQYFEPAPDNADIQKQPMTAVSREDQSVFVGFTSKLCDRNQSTTWSRALGRFHELQNFSDDD
Protein: Fumarate reductase subunit D (Fumarate reductase 13 kDa hydrophobic protein) (Quinol-fumarate reductase subunit D) (QFR subunit D) (P0A8Q3)
Organism: Escherichia coli (strain K12)
Function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. The QFR enzyme complex binds 2 quinones in or near the membrane; 1 near the [3Fe-4S] cluster (QP is proximal to the [3Fe-4S] cluster, on the cytoplasmic side of the membrane) while QD (the distal cluster) is on the other side of the membrane. It is not clear if both of the quinol-binding sites are functionally relevant.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00709, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00709, ECO:0000269|PubMed:10373108}.
Interaction partners:
- Fumarate reductase subunit C
- Fumarate reductase flavoprotein subunit
- Fumarate reductase iron-sulfur subunit
- Succinate dehydrogenase cytochrome b556 subunit
- Succinate dehydrogenase flavoprotein subunit
- Succinate dehydrogenase iron-sulfur subunit
- Succinate dehydrogenase hydrophobic membrane anchor subunit
- Succinate--CoA ligase subunit beta
- Succinate--CoA ligase subunit alpha
- Succinate-semialdehyde dehydrogenase [NADP
Sequence:
MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI
Protein: RasGTPase-activating protein (Q54I64)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSNLNINSQAQNSPDPTRRSFGTGGSGSTFSPGGSDSRIMSVNIVDIIGQQDHVKSEILAKNQKQLFDLKREISQSSKKNFTLERDIKNLDKKIALLIKNRITLEEIMNSGDIVELQTRTVTLKDKSQRDHYGQLFYLLQNNTTYIAQLAKLVKVGEIDNLLQTVMFTLYGNQYEEKEEHLLLSMFQKVLQEEFKEATSIGSLLRANTALTRMMTTYTRRGPGQQYLKQRLTKPLADITSNKDLILEVNPSTVYENYINEYETKTGKPSPLKRKVSPEECADNQNVKDIIKPRIDKLIEIGDQFLDSILSSVDAVPYGIRWICKQIRELVKQKFPQATRAQTCGLIGGFFLLRYINPAVVTPQAFMLVDAKLSNNTKRNLTFPAKMLQNLANNIMFGGVKEFFMEPLNVFLDRNKDRLNDFLESLTDVESLSDHLQLDKYLAMAKTSDITINITLNEMYFVHSLLEQHINSLAPDQNDPLRVILNDLGAAPPQLSRTENANVELKLTNRFAADHHNLPTSSSTSSSLNIGGSVGGGGGGGGGDNTSGQSNPEQVYNETKYLLITVLRSLASTPGTGDMGASLAEVAKHAALNKNQDIVDNIKKILVNVKKLSLEGYLKGEDDNFTQLRKDIVAELLNYETYISKTAKDIEKLKEVLSAIHQHNLFLQQQLDYYEKYLSNVRENCGTNASGSSDKKSKKDKDKNKDKDSSTDKATGKKAMVKKGPFKFSYNQMEKDGLICQSEVPEDRRSNIFFSFSSESPGIYDVVLIYRTTAVSEIRLQLDELLEMQSNGQTEYETTFFKLNVNLLLYVLNKTFIS
Protein: Trim24 protein (Q32PZ6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
PSFWAQNIINLGSLVIEEKESQPQMPKQNPVVEQSSQPPGGLPSNQLSKFPTQISLAQLRLQHIQQQHPPPRLINFQNHSPKPNGPVLPPYPQQLRYPPSQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQATPTTASSSSSTPSSPTITSAAGYDGKAFSSPMIDLSAPVGGSYNLPSLPDIDCSSTILLDNIARKDTSVDPGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNTNYPRSILTSLLLNSSQSSASEETVLRSDAPDSTGDQPALHHENSPNGKSEWPDASQKSPVHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLTCHVPTLTHFPSGEWICTFCRDLSKPEVEYDCDAPSHNSDKRKSEGLTKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYCMYTKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLESYFEELLKNLYPEKRFPKLEFRHDVEDCKFSDDSDDDFVQPRKKRLKSMEDRQLLK
Protein: Matrix protein (P06942)
Organism: Measles virus (strain Edmonston) (MeV) (Subacute sclerose panencephalitis virus)
Function: The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
Subcellular location: Virion {ECO:0000250|UniProtKB:Q9W850}. Host cell membrane {ECO:0000250|UniProtKB:Q9W850}.
Interaction partners:
Sequence:
MTEIYDFDKSAWDIKGSIAPIQPTTYSDGRLVPQVRVIDPGLGDRKDECFMYMFLLGVVEDSDPLGPPIGRAFGSLPLGVGRSTAKPEKLLKEATELDIVVRRTAGLNEKLVFYNNTPLTLLTPWRKVLTTGSVFNANQVCSAVNLIPLDTPQRFRVVYMSITRLSDNGYYTVPRRMLEFRSVNAVAFNLLVTLRIDKAIGPGKIIDNTEQLPEATFMVHIGNFRRKKSEVYSADYCKMKIEKMGLVFALGGIGGTSLHIRSTGKMSKTLHAQLGFKKTLCYPLMDINEDLNRLLWRSRCKIVRIQAVLQPSVPQEFRIYDDVIINDDQGLFKVL
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (Q9VLA4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Beta-glucuronidase
- Beta-glucuronidase
- cytidine deaminase
- Cytidine deaminase
- Cytidine deaminase
- UDP-glycosyltransferase family 37 member A1
Sequence:
MPRFFQLTWALLLILIGFTTAVTFIGDDPVVELSLGRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQPGVVSLMSEDCLKINVFTKSFEDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDIDNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHGVHRLVQLASHFTPVYYTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFTHFAKTGTPLNSTDIWPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKLFPTAAQGGGAALKLSFAVAIATGVASRLIGKLM
Protein: Katnb1 protein (B1WBN6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVTQDPVQASQPQTQQTPNPGVSLRRIYERPSTTCSKPQRVKHNSESERRSPSSEDDKDERESRAEIQNAEDYNEIFQPKNSISRTPPRRSEPFPAPPEDDIATAKEASKPSPAMDVQLPVPSQEVPARPSVMTSTPAPKGEPVIIPATRNEPIGLKASDFLPAVKVPQQAELVDEDAMSQIRKGHDTMCVVLTSRHKNLDTVRAVWTTGDIKTSVDSAVAINDLSVVVDLLNIVNQKACLSSSLWKLDLCTTVLPQIEKLLQSKYESYVQTGCTSLKLILQRFLPLITDILAAPPSVGVDISREERLHKCRLCFKQLKSISGLVKSRSGL
Protein: 5'-nucleotidase SurE (EC 3.1.3.5) (Nucleoside 5'-monophosphate phosphohydrolase) (Q9PF20)
Organism: Xylella fastidiosa (strain 9a5c)
Function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00060}.
Interaction partners:
- Protein-L-isoaspartate O-methyltransferase
- GMP synthase
- Uridylate kinase
- Inosine-5'-monophosphate dehydrogenase
- Bifunctional purine biosynthesis protein PurH
- Adenylate kinase
- Cytidylate kinase
- Adenylosuccinate lyase
- Guanylate kinase
- Orotidine 5'-phosphate decarboxylase
Sequence:
MRVLVSNDDGVDAPGIKILADALRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTPTDCVHLALTGLLNYDPDIVVSGINNTGNLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTLYREGQQAPQYETAAHAAINIVAQLKTDPLPADTILNVNVPDVTWQQMRGFKVTRLGNRHRSAPCLTQTDPRGHTIYWIGPAGPEQDAGPGTDFDAVRNTYISITPIHVDLTRYQALENVTRWTDRLTAHMDWPT
Protein: Desmocollin 2 (A0A3B3ISU0)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, desmosome {ECO:0000256|ARBA:ARBA00004568}. Cell membrane {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}.
Interaction partners:
Sequence:
MLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKVYLCNQDENHKHAQDYVLTYNYEGRGSVAGSVGCCSERQEEDGLEFLDNLEPKFRTLAEACMKR
Protein: ShKT domain-containing protein (O16424)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MYFLISLFFVPFSSAVIGGDLNCTTYNGTAFVYTPSATACSNSISDSSCAALYPPADAAIGYPAAGNDAERPFACYTTATPTPAPVVADMKTAALANCAKTCGFCCSTDAYNCPNVAFPRLNCNTITKAQCDSVTWRTIIAADCPSACGFCNQGGCVDAVTNCGNDLSICQTVGMQDFVNQYCQRTCGRCPSTTGSGTVTTASSGSCTSFAADSSSSCSAWAANGFCTNTFYTAAQRKSRCATSCRLC
Protein: Zinc finger LSD1-type domain-containing protein (Q583D9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPSITRCTGQIICQGCQVTLAYPIGAPSVRCPLCASVTHVRQFSVTCVQCRVVLILAQNTSLAMCPQCRVVMSIPACMRDGWSSLFPPEQCVYIERPVRAGASRTLPRIAVGTKLDDDEDP
Protein: Ral guanine nucleotide dissociation stimulator-like 1 (Q19852)
Organism: Caenorhabditis elegans
Interaction partners:
- Ras protein let-60
- small monomeric GTPase
- Raf homolog serine/threonine-protein kinase
- Mitogen-activated protein kinase kinase kinase kinase
Sequence:
MATRYWGDEKHPDAIYAVYLRKVRYVPPQGYEGVPQYHMQYFTFDKITRNFSRLPRYRAIDPDRPKTESSEMSGADHLEWESVKEKLIKAGTVERLVECLVGSDDMMDSRHFNVFFATYRSFTDSAIVLDCLLRRYETLENEVNGSTSALLVQNSIRQIVMCWLETYPEDFYDSDKDFAMLSSLLDFGGRNKLTELRAKARKQREVFKRIYDEGGMQAALPSLGQYVADMGFDPSDYPNNIKERVKMFDVGKENCVQIAEQLTFWDAALFKELLIHQCQGCVWSKRRTAGERVYTVKATIEQFNSVSQRVMTSIVLPDCRPEYRAKIISKWIDIARELRALKNFSSLKAVLSSLQSEPVHRLKSAWNSVPNRSISQFRELSSIYETDEDGDQGNARKILEQEGTAKSSPLRRPQLIQNCRRTKSDVNLAECQGTVPYLGNFLTDLAMVDESTPDYTPENLINFEKRRKEFEVLAKLRLFQSAARAYNIPMDRMFCAWFFFLPCLDENECFNRSLEIEKPPMHSTPDLSSSRINSSMLSNGSQSTPVKNSTLSRLFNSSRTSEDSGSHNGNGTWHQHSHSYSSSTNSQIPSINTGSSLNISDGGVPQHSRDSGLQCEDWIDGRLDGGPPGPVPLSGTSTLPRGSNTNTPSSANASWTGGSEFTPSSLFPYSHSRSKSGESSLQEVKTSMSTRASADGTSGTQSLSRSATPIRTRLAEVFDSKVFSHQKKGSDASSCSSSSSLSANGNSQAQNSFYLARVGLDDDLQNTDGANYKCIKIENGDRMPQLVARALEKHLIEDDKNTYLLVQLLPRGGEFVLPDNCNPFYAMAPDPTSPMLNLLLRKRDGNGTIEGGASPQLGPSAKKLNRMKRTNLLRWSSGYL
Protein: Carboxysome shell protein CcmK1 (Carbon dioxide-concentrating mechanism protein CcmK1) (P72760)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: One of the shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome. The hexamer central pore probably regulates metabolite flux.
Subcellular location: Carboxysome {ECO:0000255|HAMAP-Rule:MF_00854, ECO:0000305|PubMed:18292340}. Note=This cyanobacterium makes beta-type carboxysomes (Probable). Forms walls in the polyhedral carboxysome (Probable). {ECO:0000305|PubMed:17993516, ECO:0000305|PubMed:18292340, ECO:0000305|PubMed:19177356, ECO:0000305|PubMed:24419393}.
Interaction partners:
- Carboxysome shell vertex protein CcmL
- Carboxysome assembly protein CcmM
- Carboxysome assembly protein CcmN
- Ribulose bisphosphate carboxylase large chain
- Ribulose bisphosphate carboxylase small subunit
- Carboxysome shell protein CcmK2
Sequence:
MSIAVGMIETLGFPAVVEAADSMVKAARVTLVGYEKIGSGRVTVIVRGDVSEVQASVTAGIENIRRVNGGEVLSNHIIARPHENLEYVLPIRYTEAVEQFREIVNPSIIRR
Protein: Cysteine-tryptophan domain-containing zinc finger protein 7 (OsCW-ZF7) (Protein WIDE GRAIN 7) (A0A0P0X9Z7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional activator that acts as a positive regulator of grain size. Binds directly to the DNA core sequence 5'-CATTTC-3' found in the promoter of MADS1, and activates MADS1 transcription. Increases grain width via direct up-regulation of MADS1 expression. Promotes active chromatin modification at the MADS1 locus by increasing its level of histone H3K4me3. In GST pull-down assay, binds specifically to histone H3K4me3, but not to H3K4me1 or H3K4me2. May facilitate the recruitment of effectors to mediate gene expression.
Subcellular location: Nucleus {ECO:0000269|PubMed:28818372}. Note=Exhibits a speckle-like distribution in the nucleus. {ECO:0000269|PubMed:28818372}.
Interaction partners:
- Os01g0314700 protein
- Kinesin-like protein KIN-14I
Sequence:
MLSVRRRQEDARGVGLRGGAAAGGMEDDAELEEGEACGDETAFVDPDVALSYIDEKIQDVLGHFQKDFEGAVSAENLGSKFGGYGSFLPTYQRSPLPQTRSPPKAANVSSRSPYHQPTESMSQNTLAVAAPSVSKHNGSMVPLSDDSSKKEVHQSTKVERASSTQDSLNGLSKSSDHNRFKVRIKVGSDNGLARNNAAIYSGLGLDISSPSSIEDSPDGCGSLSPEFNNVPIESPRTILQIMTCFSVPGGFLLSPLRDDLVQLTQKVVPTSKKWETNANTENVQERYEGYAAKRVKSDAKKKKAVDTKRSKSRNDVSAVMKNEIDIETPAGQKIVLEALNIPLLSNPRTMEAKDGSQFEEDPMRDTLVENKDARLKERTINSDLMAIKYENVKAEAAECLENSGPGSSGMDFSAVKGEVKFKAEKAEIHVEDRNTTSEKDFQSDRKQERKIKTESKCNATGVNFEGNKVMNERTPVVGRSIGKVSSKETLLNDINEENVSKSESRRSQKEQNMNASSSSDFLEDDRGVLSSGAVKERKNDSQSKSSHPGRKPKAKSHRDVREHLPEGSYGGKDDTLENGSGLGELRPKKIWKNDSERDSDMPGTSKREISSSLKNDRHTPAEEQRMHVPPSVSAPTANAAPMLPAPVVIEEHWVCCDICQKWRLLPYKMNPSLLPKKWKCSMLQWLPGMNRCEVSEDETTNALNALYVSPAPGNGVASVGHSHVASSGLTTSNTLNVNGHVEQSRKRKNTLSDGNVSFDVSQQMQGSVYPLSNQHAPIRSKSAADSIQFPVERDSKSVDHFVEKKRSKSKNHGSSSDGGHLVERSKKHSKVKSKREMDHDEYRTSKKIKKEERRQRQSGIDSNPGYDLASGDVPDEAKALPSKSMALQGSSERSDVPPSKYKSVSKYNSSEKSKRSKDGDVFLPEDKNKEHSYPSDAQKPDLSSKKRIVKEWEESQHNSTPPVSKMSIVNQSSSSKETCKDQNLKETKSKLTKSEEPFAMTDSKSIKVAHSNQTSRNLNNELFEDSTPFAVKSGMSEPPENRSSEQALDLAEPASSDLAYFQTTAVTSSSSKASGSQRRKQNFHVAKTSPIESVSSSPPRISNNDKVSHDKILGKDGSTCANTNNMQSLVKNTEVIVDNVRQARKSHESMLASEPVMNGFSQGNSDKDNELPQLTQGHASNGIISGRSLDDDLQHASGRKDSSLKSSNAARSHNHLHYANKNNLLTDGSSIQHRMAVLDTKGDSMVHENKRSVTSLQDRNGSTHYPPDGNPQSEVSFGKEKSHPKSNKHDMQNSKAQMLPSPLKESKVESHSAPLRSNASKLTAQLKRGNVENGGQHGITKQAISNPADTSSPVRKDNNSTGYALKEARDLKHKANRLKEEGKEQESTRLYFESALKYLHVASTLEPPPSIDGFKQCDAAQNLYSDTAKLCNFVGHAYEKSKKMAAAALAYKCVEVAYLKAAYYKYPTASKDRQMLQAIVQNPPGESPSSSASDIDNLNNNGLSKGPSSKDANSPQVTGNNLLLAARNQPHLTRLLAYTNDVNCAFDATRKSQMAIASAASNQENGIDGLSSVKTVLDFNFQSVNDLLRLVRLSMESISC
Protein: Phosphotransferase (EC 2.7.1.-) (F1RC38)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Glucose-6-phosphatase catalytic subunit 1
- Glucose-6-phosphatase 3
- Glucose-6-phosphatase
- Glucose-6-phosphatase
- Glucose-6-phosphate isomerase
- Glucose-6-phosphate isomerase
- Phosphoglucomutase 1
- GDH/6PGL endoplasmic bifunctional protein)
- Phosphoglucomutase-2
- Glucose-6-phosphate 1-dehydrogenase
Sequence:
MPCLTSARRQRIPSDFESVLEKILMVDQILSEFVLSKEELEEVMRRMRREMERGLRVETHDEASVKMLPTYVRSTPEGSEVGDFLALDLGGTNFRVMLVKVGEDEERGWKVETKHHMYSIPEDAMTGTAEMLFDYIAGCISDFLDKHNLKHKKLPLGFTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRSCEVGMIVGTGCNACYMEEMRKVELVEGEEGRMCVNTEWGAFGDHSELEDFRLEYDRVIDETSLNPGHQLYEKLIGGKYMGELVRLVLLKLVNEDLLFNGEASDLLKTRGAFETRFVSQIESDTGDRKQIYNILSCLGILPSELDCDIVRLACESVSTRAAHLCGAGLAGVINLMRERRCQEELKITVGVDGSVYKLHPHFKERFHKLVWELTPHCEITFIQSEEGSGRGAALISAVACKMAACMLTP
Protein: Pumilio domain-containing protein 7 (O44169)
Organism: Caenorhabditis elegans
Function: RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-5 and puf-6 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.
Interaction partners:
- Pumilio domain-containing protein 5
- CCCH-type zinc finger protein oma-2
- Protein mom-2
- Embryonic mRna
- Chondroitin proteoglycan 1
- Chitin-binding domain protein cbd-1
- MEiotic SPindle
- CCCH-type zinc finger protein oma-1
- Uncharacterized protein C05C10.5
- PUM-HD domain-containing protein
Sequence:
MTPNRRSTDSYNMLGASFDFDPDFSLLSNKTHKNKNPKPPVKLLPYRHGSNTTSSDSDSYIFNSGSGSSDAETPAPVAPIFISLEDVLLNGQLIDFAIDPSGVKFLEANYPLDSEDQIRKAVFEKFTESTTLFVGLCHSRNGNFIVQKLVELATPAEQRELLRQMIDGGLLAMCKDKFACRVVQLALQKFDHSNVFQLIQELSTFDLAAMCTDQISIHVIQRVVKQLPVDMWTFFVHFLSSGDSLMAVCQDKYGCRLVQQVIDRLAENPKLPCFKFRIQLLHSLMTCIVRNCYRLSSNEFANYVIQYVIKSSGIMEMYRDTIIDKCLLRNLLSMSQDKYASHVIEGAFLFAPPALLHEMMEEIFSGYVKDVESNRDALDILLFHQYGNYVVQQMISICTAALIGKEERELPPAILLLYSGWYEKMKQRVLQHASRLERFSSGKKIIDSVMRHGVPTAAAVNAQAAPSLMELTAQFDAMFPSFLAR
Protein: Caspase 8, apoptosis-related cysteine peptidase (Caspase-8 (EC 3.4.22.61)) (Q66I19)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDPQIFHEIDENLTSGDVDQLKFLCLDFIPKRRLESVTDAKDLILRLDEQGLLEDELLFPELLITIGRIDLLEILKKSKEEVERNLLRCDNSRKGVSAYRKMLLKISEDMTEENFRAAKFLLDLPRAKLGRSTSFLDALIEMEKQQRLGPDNLDELYRILEKCDKQLAVMIERFRNQSHRDQEQGGRLPLEEVFLNNPVSETMERERRRNSSAGTITTDAETPLNPNEYYILTQRPLGYCLIINNYNFLKSTNLLKRTGTDMDKDRLAKLFSRMHFQIEVRNDLEAWAIKDEIKQFANRNHASMGAFVCCILSHGEKGTVLGTDGKPVEIREVTLPFAGCRTLASKPKLFFIQACQGDENQAGVWTSDGREDAPEEDEKYEEDAGIIVLRKIPIEADFLIGMATVEHYLSYRHTKEGSIFIQELCKKMEELCPKKEDMLSILTKVNFEVSKRILKGYKQMPEPRYTLTKKLVLPID