wanglab/gogpt-training-data huggingface dataset:
Protein: Replication factor C 38kD subunit, isoform A (Replication factor C 38kD subunit, isoform B) (Q9U9Q1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Activator 1 subunit 5
- Replication factor C subunit 2
- Enhanced level of genomic instability 1
- Replication factor C subunit 2
- Rad17
- Replication factor C subunit 1
- Sister chromatid cohesion protein DCC1
- Chromosome transmission fidelity protein 18 homolog
- Proliferating cell nuclear antigen
- DNA primase large subunit
Sequence:
MALWVDKYRPRELSKLDFHKDQAENLRNLCKQSDFPHLMFYGPSGAGKKTRIMCLLREMYGSGVERLRSETMTFTTPSNRKVEVMTVSSNYHLEVNPSDAGMYDRTVVIDLIKQVAQTHQIEISGQREFKVIVISEGDELTKDAQHALRRTMEKYVATCRIIISVNSTSRIIPAIRSRCLGIRVAAPNETEIVSILQNTCKREGLALPVELAKRVVDKSERNLRRALLMLEAAKVAKAPFTANQEIPDLDWQVFLRETASQIISEQTPAKLEKIRERLYELLTQGVPPNLIFRGLVEQLVNNCDMSIKAKTLEFATEYEHRMQSGAKHIFHLEAFVAQFMNIYKKFLSELDMTDDF
Protein: cyclin-dependent kinase (EC 2.7.11.22) (Q9CAG1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g58020
- Ubiquitin receptor RAD23
- Probable small nuclear ribonucleoprotein F
- DGCR14-like protein
- SAC3 family protein A
- Pre-mRNA-splicing factor 18
- Suppressor of mec-8 and unc-52 protein homolog 1
- Polyadenylate-binding protein RBP47B'
- RNA-binding motif protein 25
- Pre-mRNA-processing-splicing factor 8A
Sequence:
MAAGRNIRYPDHELRDQESNSRFSRRDSAYANEDYNHVRNGAIDNGKGRVSNLRHGDRDRIKSGARQEENKMVSSGFRLSKSNPGSREVFIDLGPKRCGFSARSVDREPGELSSESGSDDLIESESLAKVNGVVKEVENRAQSPVEKKRKFSPIVWDRDDHERSNLSRNEKPVEVTPLPPPPPLVKRSSQSPSVSCGGNSHYSPAKSDMHQDPVEVGVSAVSMPALSPSVEMSSLCVVEQSSNAEQDDKQEHATHLEEDENMPTRHISSSRWAAGNSSPTDEVEIVEEVGEKKRRKKPFPVQGRFRNTSQTPEVGELVREGYRSSDSDERGHHSLPGSRDDFEERDAVKSDKMEIDEEEHRRENSVDSLSETDSDDEYVRHETPEPASTPLRSINMLQGCRSVDEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQYSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVKVNFVKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFREVPLPKSKDFMPTFPAQHAQDRRGRRMVKSPDPLEEQRRKELTQTELGSGGLFG
Protein: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic (EC 2.7.7.60) (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (AtMECT) (AtMEPCT) (P69834)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Is essential for chloroplast development and required for pigments and gibberellins biosynthesis.
Subcellular location: Plastid, chloroplast stroma {ECO:0000305|PubMed:18236010}.
Interaction partners:
- 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic
- 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic
- 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic
- 1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic
- 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic
- Phosphomevalonate kinase, peroxisomal
- DNA repair protein RAD4
- 1-deoxy-D-xylulose-5-phosphate synthase
- Diphosphomevalonate decarboxylase MVD2, peroxisomal
Sequence:
MAMLQTNLGFITSPTFLCPKLKVKLNSYLWFSYRSQVQKLDFSKRVNRSYKRDALLLSIKCSSSTGFDNSNVVVKEKSVSVILLAGGQGKRMKMSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIFEEYEESIDVDLRFAIPGKERQDSVYSGLQEIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPELLKKGFELVKSEGLEVTDDVSIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILSEDS
Protein: Excisase A (NifD element site-specific recombinase) (P08862)
Organism: Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Function: Essential for DNA excision. Site specific recombinase necessary for the excision of the 11 kb nifD element during heterocyst differentiation.
Interaction partners:
- Nitrogenase molybdenum-iron protein alpha chain
- FdxN element site-specific recombinase
- [NiFe] uptake hydrogenase large subunit
- Alr1147 protein
- Asl0815 protein
- Ferredoxin-like protein in nif region
Sequence:
MQNQGQDKYQQAFADLEPLSSTDGSFLGSSLQAQQQREHMRTKVLQDLDKVNLRLKSAKTKVSVRESNGSLQLRATLPIKPGDKDTNGTGRKQYNLSLNIPANLDGLKTAEEEAYELGKLIARKTFEWNDKYLGKEATKKDSQTIGDLLEKFAEEYFKTHKRTTKSEHTFFYYFSRTQRYTNSKDLATAENLINSIEQIDKEWARYNAARAISAFCITFNIEIDLSQYSKMPDRNSRNIPTDAEILSGITKFEDYLVTRGNQVNEDVKDSWQLWRWTYGMLAVFGLRPREIFINPNIDWWLSKENIDLTWKVDKECKTGERQALPLHKEWIDEFDLRNPKYLEMLATAISKKDKTNHAEITALTQRISWWFRKVELDFKPYDLRHAWAIRAHILGIPIKAAADNLGHSMQVHTQTYQRWFSLDMRKLAINQALTKRNEFEVIREENAKLQIENERLRMEIEKLKMEIAYKNS
Protein: Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (dMED10) (dTRAP15) (Q9GYU7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for activated transcription of the MtnA, MtnB and MtnD genes.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 11
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 4
- Mediator of RNA polymerase II transcription subunit 30
Sequence:
MSAPLENLETQLEMFIENVRQIRIIVSDFQPQGQNVLNQKINSLVTGLQEIDKLRSQVQDVYVPFEVFFDYIDQDKNPQLYTKDCVEKALAKNEEVKGKIEGLKKFKTNLLLELYKTFPNEMNNYRAYRKDSM
Protein: Pyruvate dehydrogenase E1 component subunit beta (EC 1.2.4.1) (A0A384MDR8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAVSGLVRRPLREVSGLLKRRFHWTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
Protein: Splicing factor TSR1 (Q57YE1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA-binding protein, putative
- Nuclear cap-binding protein subunit 2
- RNA-binding protein, putative
- Pre-mRNA-splicing factor SLU7
- RNA-binding protein, putative
- U2 splicing auxiliary factor, putative
- Pre-mRNA splicing factor, putative
- RNA-binding protein, putative
- Cell division control protein, putative
- C3H1-type domain-containing protein
Sequence:
MDSRDGSGSDNPEVVSLYIGLGPAASTISKEQLWERLEQVAPVSDVRIRGRCAFVDVAGPEAADRLITEMDGKYIGEARMVVQHSRGSNREGERDRDRERGRERERGRHRERGRGVPFDGRGADYGGYNNSAGGRTALFVGLGPSGRSISDRELRSKLEEAAPIIGFRRRGECAFVDVPSPAHARRMIEMMHNQYMQDCRLSVQQSREGKRGRLDDDRVDRPRRRSGSRGRRRRSRNRNRNRSRSRSRSRSRSRSRSHRSNSRGRRRTRNRSRSGSPVSSRSSYSRRSSEASAGSRGYKKRDRRRRERSRSASSGSRSGSENYRKRRD
Protein: Myosin, light chain 12A, regulatory, non-sarcomeric (Predicted gene, 49909) (Q6ZWQ9)
Organism: Mus musculus (Mouse)
Interaction partners:
- Myosin-9
- Myosin light polypeptide 6
- Myosin-10
- Myosin light chain 6B
- Myosin-11
- Myosin light chain kinase 2, skeletal/cardiac muscle
- Myosin light chain kinase 3
- Actin, cytoplasmic 2
- Actin, cytoplasmic 1
- Myosin light chain kinase, smooth muscle
Sequence:
MSSKRAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEAIGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
Protein: Rhodopsin kinase grk7a (EC 2.7.11.14) (G protein-coupled receptor kinase 7-1) (G-protein-coupled receptor kinase 7A) (Q49HM9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q8WMV0}; Lipid-anchor {ECO:0000250|UniProtKB:Q8WMV0}.
Interaction partners:
- Recoverin a
- Recoverin
- Recoverin b
- Recoverin 3
- Green-sensitive opsin-4
- Green-sensitive opsin-2
- Rhodopsin
- Rhodopsin
- Green-sensitive opsin-3
- Rhodopsin.
Sequence:
MCDMGGLDNLVANTAYLKAQGGDDKEMKKRRRSLSLPKPEQCASLRTSLDKDFESLCEKQPIGKKLFRQYLSQGGPECTTAAEFLDDLNEWELSESAARDKARTNIINKFCKEGSKSSLTFLTGDVATKCKAVSDKDFEEVMGQVKTATKEFLKGKPFTEYQASPFFDKFLQWKEYEKQPISEKYFYEFRTLGKGGFGEVCAVQVKNTGQMYACKKLCKKRLKKKHGEKMALLEKKILERVNSLFIVSLAYAYDTKTHLCLVMSLMNGGDLKYHIYNIGEKGIEMDRIIYYTAQIATGILHLHDMDIVYRDMKPENVLLDSQGQCRLSDLGLAVEIAVGKTISQKAGTGAYMAPEILNETPYRTSVDWWALGCSIYEMVAGYTPFKGPDAKKEKVEKEEVQRRILNEEPKFEHKNFDAATIDIIKQFLKKKIDERLGCKNDDPRKHEWFKSINFARLEAGLIDPPWVPKPNVVYAKDTGDIAEFSEIKGIEFDAKDDKFFKEFSTGAVSIAWQQEMIDTGLFDELSDPNRKESSGGSDDDKKSGTCTLL
Protein: Phosphatidylserine decarboxylase proenzyme 3 (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase 3 beta chain; Phosphatidylserine decarboxylase 3 alpha chain] (A4GNA8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Contributes only to a minor proportion of PtdEtn production.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:17449644}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
- CDP-diacylglycerol--serine O-phosphatidyltransferase 1
- Choline/ethanolaminephosphotransferase 1
- Choline/ethanolaminephosphotransferase 2
- Lysophospholipid acyltransferase 1
- Lysophospholipid acyltransferase 2
- Lecithin-cholesterol acyltransferase-like 4
- Phospholipase A
- Phospholipase D gamma 1
- Phospholipase D alpha 2
Sequence:
MGNGNSTETKESRRSKMRKKIQNFRSRRRLSRPGSGSVSGLASQRSVSADDFAGIALLTLIGAEMKFKDKWLACVSFGEQTFRSEISDSTEKPIWNSEKKLLLEKNGPSLARISVFETNRLLKNNIVGYCELDLLDFVVQEPDSTCKSFDLLDPASSNVVGSMFVSCSVEDPVETETCFAKRILSIVDYDEDGKLSFSEFSDLMNAFGNVVAANKKEELFKAADLNGDGVVTIDELAALLAVQQEQEPIINSCPVCGEALQLDKLNAMIHMTLCFDEGTGNQMTGGFLTDRQASYGWMFKLSEWTHLSTYDVGLNTGSSASHIVVIDRKTKRLVEELIDSKIVMSMRAIYQSKIGLRLMDQGAKEILQNLSEKQGKKMNSVESAQNIPSFLEFFKDQINMAEVKYPLDHFKTFNEFFVRELKPGARPIACMDQDDVAVSAADCRLMAFQSVDDSTRFWIKGRKFSIKGLLGNDVQSDAFLDGSLVIFRLAPQDYHRFHSPVSGVIEKFVNVSGSLYTVNPIAVNSKYCNVFTENKRTIVIISTAEFGKVAFVAIGATMVGSISFVRQEGDHVKKGDELGYFSFGGSTVICVFEKDSIKIDEDLLANSARSLETLVTVGMQLGVSFPKLENCVLEP
Protein: HTH-type transcriptional regulator MalR (Maltose operon transcriptional repressor) (P0A4T1)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP.
Interaction partners:
Sequence:
MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKELNYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIATGKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPLVDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNRIYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDSVNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK
Protein: 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial (Mitochondrial tRNA translation optimization 1) (Protein MTO1 homolog, mitochondrial) (Q923Z3)
Organism: Mus musculus (Mouse)
Function: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14522080}.
Interaction partners:
- 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial
- Mitochondrial tRNA-specific 2-thiouridylase 1
- Vacuolar protein sorting-associated protein 45
- VCP nuclear cofactor family member 1
- STAGA complex 65 subunit gamma
- Probable cysteine--tRNA ligase, mitochondrial
- Coiled-coil domain-containing protein 127
- TNF receptor-associated factor 4
- Methionyl-tRNA formyltransferase, mitochondrial
- tRNA dimethylallyltransferase
Sequence:
MFLLRGRGHWAAASLGRRLPLRRLRSDSAAPCTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILSTPLLTVQKGAVEDLVLAEPEPGYPGKSRVRGVVLADGSTIYAESVILTTGTFLRGMIIIGLEMHPAGRLGDQPSIGLAQTLEKLGFMVGRLKTGTPPRLGKESINFSILNKHTPDDPSIPFSFLSDSVWIKPEDQLPCYLTHTNPRVDAIVLENLHLNSHVQETTKGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHPGYGVQYDYLDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHKEAGCVSSQRFERALWMKSSLEEGISVLKSIKFSSSKWKKLIPQIPISINRSLPVSALDVLKYEEVDMESLVGVLPEPLEKYTACRELARRLKIEASYESVLSYQLQEIKEVQQDEALQLPHELDYLTIRDVSLSQEVREKLHLSRPQTIGAASRIPGVTPAAIINLLRFVRSTRQSRQQ
Protein: Solute carrier family 3 member 2b (Zgc:55813) (Q6P3H9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Cystine/glutamate transporter
- Cystine/glutamate transporter
- Solute carrier family 2 member 3b
- Large neutral amino acids transporter small subunit 1
- Solute carrier family 3 member 2a
- Zgc:158423.
- Solute carrier family 2 member 3a
- 11-beta-hydroxysteroid dehydrogenase type 2
Sequence:
MSNDTEVDMKDVELNEVEQEKQPMTEGDAGNNYAISPVTEKNGIVKVKIPDEESKFTGLSKEELMKVAGTPGWVRVRWALLILFWLGWLGMLAGAIAIIIQAPRCKPLPEMNWWNNGPLYQIGDVGAFTNSSDIKDLAGKVQALDDLKVKGLIIGPIHVSSEDKPNELNLIKISEDDGVLAQFKEVITAAHKRGISVILDLTPNYKGKDPWFSDAVNTVQKVEPALIFWLKQGVDGFLFYGVEKVAAAAPTFWSDVVALIHNQTDAEGKTKKVLIGVTDQSSPEEISATLNKTGVDLLLSGALRSKSVQEVAQAVESLYSTYNQTRLAWNIGGRIAGHLASVVGFAKVKLSQLMLLTLPGTPVFNYGDEIGLEDEVNKYPTMLWKFNDEEKQKEMSTYHSFFKSVSVKRMKERSLQHGEYLPLFNSDFAMAYVRSWDQNERYLIALNWHSNETVSLQLKHADIPESATVVFSTSGETEVNKELNLAQLEVNPGEGIMLKFPYTS
Protein: Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B) (Q6Y1H2)
Organism: Homo sapiens (Human)
Function: Catalyzes the third of the very long-chain fatty acids (VLCFA) elongation four-step cycle (condensation, reduction, dehydration, and reduction). This endoplasmic reticulum-elongation process is characterized by the addition of two carbons to the lipid chain through each cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of elongation. Therefore, it participates in the production of various VLCFAs involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15024066, ECO:0000269|PubMed:18554506}; Multi-pass membrane protein {ECO:0000269|PubMed:15024066, ECO:0000269|PubMed:18554506}.
Interaction partners:
- Very-long-chain enoyl-CoA reductase
- Very-long-chain 3-oxoacyl-CoA reductase
- Very long chain fatty acid elongase 6
- Very long chain fatty acid elongase 4
- Very long chain fatty acid elongase 2
- Stearoyl-CoA desaturase
- Very-long-chain
- Very-long-chain
- Stearoyl-CoA desaturase 5
- Acyl-CoA
Sequence:
MAAVAATAAAKGNGGGGGRAGAGDASGTRKKKGPGPLATAYLVIYNVVMTAGWLVIAVGLVRAYLAKGSYHSLYYSIEKPLKFFQTGALLEILHCAIGIVPSSVVLTSFQVMSRVFLIWAVTHSVKEVQSEDSVLLFVIAWTITEIIRYSFYTFSLLNHLPYLIKWARYTLFIVLYPMGVSGELLTIYAALPFVRQAGLYSISLPNKYNFSFDYYAFLILIMISYIPIFPQLYFHMIHQRRKILSHTEEHKKFE
Protein: HTH-type transcriptional regulator Rv0792c (O86331)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Transglutaminase-like domain-containing protein
- Conserved protein
- Putative monooxygenase Rv0793
- YbjN domain-containing protein
- UPF0603 protein Rv2345
- Uncharacterized HTH-type transcriptional regulator Rv0494
- HTH-type transcriptional regulator RipA
- Putative antitoxin HigA3
- Probable transcriptional regulatory protein
- Uncharacterized HTH-type transcriptional regulator Rv2912c
Sequence:
MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPVEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVEVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Protein: Protopanaxadiol 6-hydroxylase (P6H) (EC 1.14.14.121) (Cytochrome P450 CYP716A53v2) (Protopanaxatriol synthase) (PgPPTS) (I7CT85)
Organism: Panax ginseng (Korean ginseng)
Function: Component of the dammarane-type triterpene saponins (e.g. PPT-type ginsenosides or panaxosides) biosynthetic pathway. Catalyzes the formation of protopanaxatriol from protopanaxadiol during ginsenoside biosynthesis, a class of tetracyclic triterpenoid saponins.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDLFISSQLLLLLVFCLFLFWNFKPSSQNKLPPGKTGWPIIGETLEFISCGQKGNPEKFVTQRMNKYSPDVFTTSLAGEKMVVFCGASGNKFIFSNENKLVVSWWPPAISKILTATIPSVEKSKALRSLIVEFLKPEALHKFISVMDRTTRQHFEDKWNGSTEVKAFAMSESLTFELACWLLFSINDPVQVQKLSHLFEKVKAGLLSLPLNFPGTAFNRGIKAANLIRKELSVVIKQRRSDKLQTRKDLLSHVMLSNGEGEKFFSEMDIADVVLNLLIASHDTTSSAMGSVVYFLADHPHIYAKVLTEQMEIAKSKGAEELLSWEDIKRMKYSRNVINEAMRLVPPSQGGFKVVTSKFSYANFIIPKGWKIFWSVYSTHKDPKYFKNPEEFDPSRFEGDGPMPFTFIPFGGGPRMCPGSEFARLEVLIFMHHLVTNFKWEKVFPNEKIIYTPFPFPENGLPIRLSPCTL
Protein: Gamma-aminobutyric acid receptor subunit theta (GABA(A) receptor subunit theta) (GABAAR subunit theta) (Q9UN88)
Organism: Homo sapiens (Human)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular location: Postsynaptic cell membrane; Multi-pass membrane protein {ECO:0000255}. Cell membrane; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Huntingtin-associated protein 1
- Trafficking kinesin-binding protein 2
- Vesicle-fusing ATPase
- Inactive phospholipase C-like protein 1
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit gamma-2
- Gamma-aminobutyric acid receptor subunit gamma-3
- Gamma-aminobutyric acid receptor subunit alpha-3
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid receptor subunit epsilon
Sequence:
MGIRGMLRAAVILLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRRVIARYRYQQVVVGNVQDGLINVEDGVSSLPITPAQAPLASPESLGSLTSTSEQAQLATSESLSPLTSLSGQAPLATGESLSDLPSTSEQARHSYGVRFNGFQADDSIIPTEIRNRVEAHGHGVTHDHEDSNESLSSDERHGHGPSGKPMLHHGEKGVQEAGWDLDDNNDKSDCLAIKEQFKCDTNSTWGLNDDELMAHGQEKDSSSESEDSCPPSPGCSFTEGFSFDLFNPDYVPKVDKWSRFLFPLAFGLFNIVYWVYHMY
Protein: Fgr29p (Q5A5T3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Galactose oxidase
- Uncharacterized protein
- Formin-binding protein
- Kinesin-like protein
Sequence:
MFRHHRDVSSHLNRQHDFRDDYYKIQRLINDKVHLSLKFEQLKSPEIHSTLMKPITDEILRISELSSSPLAAYLQHDTQPEIIGSSSLAVTERRDSRLGRSTYTTLDAVSRETIEGPRQKVSNNVIFILLLLRYEYLIQSENNLVCFDLLITKATVCELLSIRMLREYKSLNRVNMLFIKPLYEVDQQYNFNTLELSVLCNAKKFLSQPIIVRILERFYNGELINNESSHMTGSGMSYTDDEKGLLEADCVTDYQFRRISYKQIIKRANTVPKYQSIVINFKLIMLSIFYFSLIFGNPMGIGTLFWIIGLSFNIELITKLYNIEWQFVRTIIWNYIDFCLIFLIDLSFALKIANTPYFSDVFSLIGIILFPRILSIFNNYKFFNLIVLSFNKMIWNLVGLIFFFFTLISGFYFSFLTLSINQAKGEILFDMVKIFFGFTPSVWNNWENYNLLGKFTLMGYLFLIQFIVGTILAICLSGVFAKVRDSNQEEFNYFKTTNLILYFKMARLNNSNNWTNSFLHIFKIPIIVILFGYELIKSKSFHKQISSELKNFTFLKQDEDNIQGTGHEVDGESNIMGRSTKRRLSRRYNKYQSLSTLNGGNIRTASTDSFFINELLNKRYGGKIEKVRTNTSERVISRKFLQQPFAVPRQPQPQAQHQQPLQNIQTSRQQSPPSIISSSPHSSSHNNNNNFGTVTDNILTRLNNLENNIAKRTLMSTSVDDNKSIMMYNINEIENNDSNEEISINSQEMDSPEDEFESSKDNTMEDIDQYDSDETF
Protein: 182 kDa tankyrase-1-binding protein (Q9C0C2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus. Cytoplasm, cytoskeleton. Chromosome. Note=Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.
Interaction partners:
- CCR4-NOT transcription complex subunit 11
- CCR4-NOT transcription complex subunit 7
- Poly [ADP-ribose] polymerase tankyrase-1
- CCR4-NOT transcription complex subunit 6-like
- CCR4-NOT transcription complex subunit 10
- CCR4-NOT transcription complex subunit 3
- CCR4-NOT transcription complex subunit 2
- CCR4-NOT transcription complex subunit 9
- CCR4-NOT transcription complex subunit 1
- Protein Tob1
Sequence:
MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQGAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQDANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPGERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDWSGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQKESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV
Protein: RNA editing complex protein MP67 (Q38B71)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- REH2-associated factor 2
- RNA editing associated helicase 2
- RNA editing complex protein
- RNA editing complex protein MP63
- RNA-editing ligase 1, mitochondrial
- MP18 RNA editing complex protein
- RNA editing complex protein MP46
- RNA-editing-associated protein 1
- RNA-editing ligase 2, mitochondrial
- RNA editing complex protein MP61
Sequence:
MRNSLIQHTRNLSATKQITGIVCDHVDVFTWGHSPPEQHGNKFSSGKATAPFYNAGQRRCTLCDDRLETSFSAHCGYVGHVARVGILERAMEILQKGEKRAANGKSGGLGGKITDLDESIKALVGTWWSRLNDTKREPALDYKRIPSLSASTTKKRLWRMRFLLQYLRDRGIIRYSLTPAKVAGAGDNAFVRSARFERSEMIGDNIVKVVVPDRLVRLFPADEGGVTYKLASIQQLLDSNEGLLEIYDYLGLNNIIGVRLPNNKTKSDVVEALFGELQTFLWASELSCGSCQYPAFPTAEHRYVRALVDHLLNELTHMVIMWRVESTLENSKEYLAKYLLQGARQNGSFSTSASGATIVKEVDCDRSRYAVLPLLLTFPYSTSSANKSAGGKQPPLQSSSLAAAKSVQERGTPRMLFTSPVAMPAVLHSHYNPPLRIVRTIKDYQREILTVLEEEEVVSALIPCTDSSWGMKEGNMNSRETGRRKPPHGQIRAPWHELALEKYPRWRCDTEEAVVRQALELRLMQRKVYTKETNWRALTTAMAQRLLPNSPLEVDPVGVRPVRQTGRLLLTFEGTTERRAALATSMCFPSLAQSAG