wanglab/gogpt-training-data huggingface dataset:
Protein: At5g11860 (SCP1-like small phosphatase 5) (Q9LYI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transcription initiation factor IIF subunit alpha
- Transcription factor GTE9
- At5g17540
- Mitotic checkpoint protein BUB3.1
- Phosphatidate phosphatase PAH1
- Phosphatidate phosphatase PAH2
- U-box domain-containing protein 33
- Receptor-like serine/threonine-protein kinase ALE2
- Fatty acid amide hydrolase
- U-box domain-containing protein 35
Sequence:
MEDDDSPSSRDLDAQNPYDRLLALDTSTVDPNCNLDSVSAIYLAMKSSKLECVDERGQDSLITSVCMEDEEDEELDEFDPYLFIKNLPNLSSVVPTFRPVLLPKQTRSCPPISLVLDLDETLVHSTLEPCGEVDFTFPVNFNEEEHMVYVRCRPHLKEFMERVSRLFEIIIFTASQSIYAEQLLNVLDPKRKLFRHRVYRDSCVFFDGNYLKDLSVLGRDLSRVIIVDNSPQAFGFQVENGVPIESWFNDPSDKELLHLLPFLESLIGVEDVRPMIAKKFNLREKIDAAVAAPEYPAEAGDPFER
Protein: GTP-binding protein 1 (G-protein 1) (GP-1) (GP1) (O00178)
Organism: Homo sapiens (Human)
Function: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Pancreatic secretory granule membrane major glycoprotein GP2
- NPC intracellular cholesterol transporter 1
- Platelet glycoprotein V
- Dystroglycan 1
- Platelet glycoprotein IX
- Transferrin receptor protein 1
- Platelet glycoprotein VI
- Exosome complex exonuclease RRP44
- Platelet glycoprotein 4
- Protocadherin-7
Sequence:
MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELDLTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQGACVTPASGC
Protein: Contactin-1 (Neural cell recognition molecule F11) (P14781)
Organism: Gallus gallus (Chicken)
Function: Mediates cell surface interactions during nervous system development. Interaction with TNR enhances the neurite outgrowth.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
- Neuronal cell adhesion molecule
- Protein-tyrosine-phosphatase.
- Contactin associated protein 1.
- Neurofascin
- Tenascin-R
- Receptor-type tyrosine-protein phosphatase gamma
Sequence:
MRFFISHLVTLCFIFCVADSTHFSEEGNKGYGPVFEEQPIDTIYPEESSDGQVSMNCRARAVPFPTYKWKLNNWDIDLTKDRYSMVGGRLVISNPEKSRDAGKYVCVVSNIFGTVRSSEATLSFGYLDPFPPEEHYEVKVREGVGAVLLCEPPYHYPDDLSYRWLLNEFPVFIALDRRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPQADRAKVYPADIKVKFKDTYALLGQNVTLECFALGNPVPELRWSKYLEPMPATAEISMSGAVLKIFNIQYEDEGLYECEAENYKGKDKHQARVYVQASPEWVEHINDTEKDIGSDLYWPCVATGKPIPTIRWLKNGVSFRKGELRIQGLTFEDAGMYQCIAENAHGIIYANAELKIVASPPTFELNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTELLVNGSRIHIWDDGSLEIINVTKLDEGRYTCFAENNRGKANSTGVLEMTEATRITLAPLNVDVTVGENATMQCIASHDPTLDLTFIWSLNGFVIDFEKEHEHYERNVMIKSNGELLIKNVQLRHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGIRIEEIRDTAVALTWSRGTDNHSPISKYTIQSKTFLSEEWKDAKTEPSDIEGNMESARVIDLIPWMEYEFRIIATNTLGTGEPSMPSQRIRTEGAPPNVAPSDVGGGGGSNRELTITWMPLSREYHYGNNFGYIVAFKPFGEKEWRRVTVTNPEIGRYVHKDESMPPSTQYQVKVKAFNSKGDGPFSLTAVIYSAQDAPTEVPTDVSVKVLSSSEISVSWHHVTEKSVEGYQIRYWAAHDKEAAAQRVQVSNQEYSTKLENLKPNTRYHIDVSAFNSAGYGPPSRTIDIITRKAPPSQRPRIISSVRSGSRYIITWDHVKAMSNESAVEGYKVLYRPDGQHEGKLFSTGKHTIEVPVPSDGEYVVEVRAHSEGGDGEVAQIKISGATAGVPTLLLGLVLPALGVLAYSGF
Protein: Phosphatidyl serine synthase, putative (Q57WJ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
- phosphatidylserine decarboxylase
- Ethanolaminephosphotransferase, putative
- Choline dehydrogenase, putative
Sequence:
MYTPRTLSVLIVLLAVFLFMVRYCHYLDMDVVSSVKLGLAASGVSFIAFGATHLPDSMLLRPHPSFWRAVLAVGVLYLALLSFLLFQSLDTIRAILLLHDPSLKSLPEERQYAEDCRIFTSDDPFLFVRTTFDIFIVAHTLGYFAKTIIVRDWRASTCISVVFEIVEVTFQHALPNFKECWWDHLLLDVLICNGGGTLLGILALRIFHARRYNWVLSDNVKSKCGKARRFISQLVPQSLVPYEWNVFLSPKRFVQFLLLLSLMTLQELNTFTVKHILHIPPKHHLVVLRLVMWLFLAIPAVCEYYFYISGLDPTNKLGPSVWVSVVNLLFEVVLAGKLAVEGNYFQEPMPGYIAIPWIISLISLCIWFAIFFGVLTLKQRMEKRCLLYAISSVFFYFGCGCVLAMFAMGMPDLQIGREAFQRYVYPYERYIIFWR
Protein: Dapper 1-B (xDpr) (Dapper1a) (XDpr1a) (Q8QG92)
Organism: Xenopus laevis (African clawed frog)
Function: Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Binds to dvl2 to regulate the degradation of beta-catenin (ctnnb1-A and possibly ctnnb1-B), thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway. Seems to promote beta-catenin degradation if not phosphorylated and to block beta-catenin degradation if phosphorylated by CaMK1D. Involved in regulation of catenin delta/ctnnd1 protein level. May also bind to and directly stimulate the activity of tcf7l1-A. Also regulates the activation by dvl2 of jnk, a component of ctnnb1/beta-catenin-independent frizzled signaling. Required for notochord and head formation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11970895}. Nucleus {ECO:0000269|PubMed:11970895}.
Interaction partners:
Sequence:
MKPIPAAPEPLGQHQDSPRRKDKGEAESERQRTRERLEATLAGLAELGHLRHRQEVLIKSVLSPGTRTHGDAAARTGDNPRSLEEKFLEDNILLLKKQLNCLRKRDAGLLSQLHELDKQINDLRIDVEKTEEHLETDSRPSSGFYELSDGTSGSLSNSSNSVFSECLSSCHSSTCFCNPLETSLNLTDGQAKSADDFLEWLDYRESQHETGTVRRSFSAPHSNSVDIEADVHPKYQCDLVSKNGNDIYRYPSPLHAVAVQSPMFLLSVMGNIKAEEPEEGIDHNDNDDCIVPELDHLKDEDSFLHQSSLCSLPLSSAKKMDGYILSIIQKKAHPVRTNKPRTSVNADPGKGILRHGSMCVKQTGGVSQSNAVNLKNSKQTCLHSTGMIAVDNSTYPSLKQCSKESLSEQLESKRMPSISTYPSCNVNELQSQNNSRNTVKSVCQGLARGSVAMTSNVQKENVTPNALANLSNTSSSVCNVTPGESMQNSPLLPQEIKVVPPVKRVSPQNTLLSYHASSSFDERPPLDFKSEGSSSQSLDEGLLVNAHYIPAQQQGVKLHKHTKYVKIVKSSTLKHRANVQYVAENGSQTLKEKSKVVGKKCRFPDDLDTNKKVKKSTLRVKKTAHPHFEPAVVGRNPVAVRSGSKSHGHSKDVVLAKPKHKRGDYRRWKSSAEISYEEALRRARRRAQGEMVGVYAQVPFPYSSPYAYIASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSLSEVEFVGESTTSSDTDESGGLIWSQFVQTLPMQATATAELQTTAKAFVKIKASHNLKKKILRFRSGSLKLMTTV
Protein: Lon protease homolog 3, mitochondrial (EC 3.4.21.53) (Q9M9L8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
Subcellular location: Mitochondrion matrix {ECO:0000255|HAMAP-Rule:MF_03120}.
Interaction partners:
- B3 domain-containing protein At3g06220
- Dof zinc finger protein DOF5.7
- CLP protease regulatory subunit CLPX1
- Probable glutamyl endopeptidase, chloroplastic
- signal peptidase I
- Signal peptidase complex catalytic subunit SEC11
Sequence:
MMPKRFNTSGFDTTLRLPSYYGFLHLTQSLTLNSRVFYGARHVTPPAIRIGSNPVQSLLLFRAPTQLTGWNRSSRDLLGRRVSFSDRSDGVDLLSSSPILSTNPNLDDSLTVIALPLPHKPLIPGFYMPIHVKDPKVLAALQESTRQQSPYVGAFLLKDCASTDSSSRSETEDNVVEKFKVKGKPKKKRRKELLNRIHQVGTLAQISSIQGEQVILVGRRRLIIEEMVSEDPLTVRVDHLKDKPYDKDNAVIKASYVEVISTLREVLKTNSLWRDQDIGDFSYQHLADFGAGISGANKHKNQGVLTELDVHKRLELTLELVKKQVEINKIKETDDGSSLSAKIRVRIDTKRDKIPKHVIKVMEEEFTKLEMLEENYSDFDLTYNYLHWLTVLPWGNFSYENFDVLRAKKILDEDHYGLSDVKERILEFIAVGRLRGTSQGKIICLSGPPGVGKTSIGRSIARALDRKFFRFSVGGLSDVAEIKGHCQTYVGAMPGKMVQCLKSVGTANPLILFDEIDKLGRCHTGDPASALLEVMDPEQNAKFLDHFLNVTIDLSKVLFVCTANVIEMIPGPLLDRMEVIDLSGYVTDEKMHIARDYLVKKTCRDCGIKPEHVDLSDAALLSLIENYCREAGVRNLQKQIEKIYRKVALELVRQGAVSFDVTDTKDTKSLAKTDSEVKRMKVADIMKILESATGDSTESKTKQSGLVAKTFEKVMIDESNLADYVGKPVFQEEKIYEQTPVGVVMGLAWTSMGGSTLYIETTFVEEGLGKGGLHITGQLGDVMKESAQIAHTVARRIMFEKEPENLFFANSKLHLHVPEGATPKDGPSAGCTMITSFLSLAMKKLVRKDLAMTGEVTLTGRILPIGGVKEKTIAARRSQIKTIIFPEANRRDFEELAENMKEGLDVHFVDEYEKIFDLAFNYDH
Protein: Alpha-glucan water dikinase 1, chloroplastic (EC 2.7.9.4) (Protein starch excess 1) (Protein starch-related R1) (Q9SAC6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates the incorporation of phosphate into starch-like alpha-glucan, mostly at the C-6 position of glucose units. Acts as an overall regulator of starch mobilization. Required for starch degradation, suggesting that the phosphate content of starch regulates its degradability.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:11487701}. Note=Starch granules. {ECO:0000269|PubMed:11487701}.
Interaction partners:
- 4-alpha-glucanotransferase DPE2
- Isoamylase 3, chloroplastic
- Phosphoglucan phosphatase DSP4, chloroplastic
- 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic
- Maltose excess protein 1, chloroplastic
- Alpha-amylase 3, chloroplastic
- Phosphoglucomutase, chloroplastic
- Alpha-glucan phosphorylase 2, cytosolic
- Alpha-glucan phosphorylase 1
- Probable starch synthase 4, chloroplastic/amyloplastic
Sequence:
MSNSVVHNLLNRGLIRPLNFEHQNKLNSSVYQTSTANPALGKIGRSKLYGKGLKQAGRSLVTETGGRPLSFVPRAVLAMDPQAAEKFSLDGNIDLLVEVTSTTVREVNIQIAYTSDTLFLHWGAILDNKENWVLPSRSPDRTQNFKNSALRTPFVKSGGNSHLKLEIDDPAIHAIEFLIFDESRNKWYKNNGQNFHINLPTERNVKQNVSVPEDLVQIQAYLRWERKGKQMYNPEKEKEEYEAARTELREEMMRGASVEDLRAKLLKKDNSNESPKSNGTSSSGREEKKKVSKQPERKKNYNTDKIQRKGRDLTKLIYKHVADFVEPESKSSSEPRSLTTLEIYAKAKEEQETTPVFSKKTFKLEGSAILVFVTKLSGKTKIHVATDFKEPVTLHWALSQKGGEWLDPPSDILPPNSLPVRGAVDTKLTITSTDLPSPVQTFELEIEGDSYKGMPFVLNAGERWIKNNDSDFYVDFAKEEKHVQKDYGDGKGTAKHLLDKIADLESEAQKSFMHRFNIAADLVDEAKSAGQLGFAGILVWMRFMATRQLVWNKNYNVKPREISKAQDRLTDLLQDVYASYPEYRELLRMIMSTVGRGGEGDVGQRIRDEILVIQRKNDCKGGIMEEWHQKLHNNTSPDDVVICQALMDYIKSDFDLSVYWKTLNDNGITKERLLSYDRAIHSEPNFRGEQKDGLLRDLGHYMRTLKAVHSGADLESAIQNCMGYQDDGEGFMVGVQINPVSGLPSGYPDLLRFVLEHVEEKNVEPLLEGLLEARQELRPLLLKSHDRLKDLLFLDLALDSTVRTAIERGYEQLNDAGPEKIMYFISLVLENLALSSDDNEDLIYCLKGWQFALDMCKSKKDHWALYAKSVLDRSRLALASKAERYLEILQPSAEYLGSCLGVDQSAVSIFTEEIIRAGSAAALSSLVNRLDPVLRKTANLGSWQVISPVEVVGYVIVVDELLTVQNKTYDRPTIIVANRVRGEEEIPDGAVAVLTPDMPDVLSHVSVRARNGKICFATCFDSGILSDLQGKDGKLLSLQPTSADVVYKEVNDSELSSPSSDNLEDAPPSISLVKKQFAGRYAISSEEFTSDLVGAKSRNIGYLKGKVPSWVGIPTSVALPFGVFEKVISEKANQAVNDKLLVLKKTLDEGDQGALKEIRQTLLGLVAPPELVEELKSTMKSSDMPWPGDEGEQRWEQAWAAIKKVWASKWNERAYFSTRKVKLDHDYLCMAVLVQEVINADYAFVIHTTNPSSGDSSEIYAEVVKGLGETLVGAYPGRSLSFICKKNNLDSPLVLGYPSKPIGLFIRRSIIFRSDSNGEDLEGYAGAGLYDSVPMDEEDQVVLDYTTDPLITDLSFQKKVLSDIARAGDAIEKLYGTAQDIEGVIRDGKLYVVQTRPQV
Protein: Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1) (Q4WPF2)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9. Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P53104}. Preautophagosomal structure membrane {ECO:0000250|UniProtKB:P53104}; Peripheral membrane protein {ECO:0000250|UniProtKB:P53104}.
Interaction partners:
- Autophagy-related protein 2
- Autophagy-related protein 13
- Autophagy-related protein 8
- Autophagy-related protein 9
- Autophagy protein Apg6, putative
- Serine/threonine-protein kinase TOR
- Autophagy-related protein 101
- Autophagy protein 5
- Autophagy-related protein 11
- Ubiquitin-like protein ATG12
Sequence:
MTSTHHSRRSRETPQPEMSIGRYTRLDEIGRGSFATVYQGVHTKTRTYVAIKSVNLSKLNKKLKDNLSSEIHILKGLYHPHIVALIDCHETTSHIHLVMEYCALGDLSLFIKRRDTLGDHRYTRDMIAKYPNPPGGALNEVVVRHFLKQLASALKFLRDRNLIHRDIKPQNLLLCPSPSSYRSGVTQVVPFKGSEDSFNPATGLESLPLLKIADFGFARSLPATSLAETLCGSPLYMAPEILRYEKYDAKADLWSVGTVLYEMVVGKPPFRATNHVELLRKIEKGEDRIKFPEENPASDEIKALIRALLKRNPVERLNFPDFFQNGVITSPIPGLVADDLPSIPQGPPADPETAEATPRPDSRSGATVPGGTEREREGPSLPKGDTGLTQRPPSQNQRFGTPQTTTPMRRIGSGDRPPSTPKESTPPMTYPQRPSAVSHATAPGRQELVDRNATFTAMERQKGRNTFSEGSPQIDRQADKLREERERAAQDVAFERDYVVVEKRAVEVNAFADELAHSPRIQGNISRGAQTGALSRRSTVHGPTPSNPSPPQATVGKAMQVLSGRSRADSMHNRQGSYERRYGQSPTSATSAISKALNMASGRLFGMGFSPPLAITKGGRSPPLAYNPFPAYPAHGSLMIGDGAKSNLALDEDTKTVQILEECATRSDVVYGFAEVKYKQLVPLAPSVQTDPSSKLNLAGERENPDSADGGLTVDAIVTLSEEALVLYVKALSLLAKSMDIAGAWWARKNRGDGFGDSAMSRANGASTLAGTRINNVVQWIRNRFNEVLEKGEFVRLKLIEAQKRLPPDHPSHPDNHSVGSSLGSGASVDVVVSPGVSAEKLMYDRALEMSRTAAINELTGEDLSGCEIAYVTAIRMLEAVLENGEVPRFGQDKDDTSKDSDKIVLDAVQADERQVVIKLLTIQAVVASIRSRLAALRKKLAILAKRAPTPSANVPSKMASSNPVSVGATPPK
Protein: Zyxin (A0A8I6GKY5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MRREAAGGPLQSLRPRAGPGPLPGGVSCPALPPRPLPAPSPGRSLYGLGAALSPPPPSLPLRVVPPRLARSCSGPGRRVRGLGAEAVIRDAALTLLPAPGLTMAAPRPPPAISVSVSAPAFYAPQKKFAPVVAPKPKVNPFRPGDSESPVAAGAQRAQMGRVGEIPPPPPEDFPLPPPPVIGEGDDSEGALGGAFPPPPPPLIEEPFPPAPLEEDIFPSPPPPLEEEGGPEAPTQLPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFVPKPSTKPAPVGTAPLPPWKAPSSSQPPPQPQAKPQVQLHAQPQAKPHVQPQSVSSANTQPRGPLSQAPTPAPKFAPVAPKFTPVASKFSPGAPSGPGPQPSQKSVPLEAPSSVGTGSPQPPSFTYAQQKEKPLVQEKQHPLPPPAQNQNQVRSPGGPGPLTLKEVEELEQLTQQLMQDMEHPQRQSVAVNESCGKCSQPLARAQPAVRALGQLFHITCFTCHQCQQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGQPITDRMLRATGKAYHPHCFTCVVCACPLEGTSFIVDQANQPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKALSIEADDNGCFPLDGHVLCRKCHSARAQT
Protein: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (GFAT) (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (Hexosephosphate aminotransferase) (P53704)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).
Interaction partners:
- Glucosamine 6-phosphate N-acetyltransferase
- Glucosamine-6-phosphate isomerase
- N-acetylglucosamine-6-phosphate deacetylase
- Glutamine synthetase
- Glucose-6-phosphate isomerase
- Mannose-6-phosphate isomerase
- Phosphoacetylglucosamine mutase
- Glutamate synthase
- Amidophosphoribosyltransferase
- N-acetylglucosamine kinase 1
Sequence:
MCGIFGYVNFLVDKSKGEIIDNLIEGLQRLEYRGYDSAGIAVDGKLTKDPSNGDEEYMDSIIIKTTGKVKVLKQKIIDDQIDRSAIFDNHVGIAHTRWATHGQPKTENCHPHKSDPKGEFIVVHNGIITNYAALRKYLLSKGHVFESETDTECIAKLFKHFYDLNVKAGVFPDLNELTKQVLHELEGSYGLLVKSYHYPGEVCGTRKGSPLLVGVKTDKKLKVDFVDVEFEAQQQHRPQQPQINHNGATSAAELGFIPVAPGEQNLRTSQSRAFLSEDDLPMPVEFFLSSDPASVVQHTKKVLFLEDDDIAHIYDGELRIHRASTKSAGESTVRPIQTLEMELNEIMKGPYKHFMQKEIFEQPDSAFNTMRGRIDFENCVVTLGGLKSWLSTIRRCRRIIMIACGTSYHSCLATRSIFEELTEIPVSVELASDFLDRRSPVFRDDTCVFVSQSGETADSILALQYCLERGALTVGIVNSVGSSMSRQTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSNDSISRKGRHEEIIKGLQKIPEQIKQVLKLENKIKDLCNSSLNDQKSLLLLGRGYQFATALEGALKIKEISYMHSEGVLAGELKHGILALVDEDLPIIAFATRDSLFPKVMSAIEQVTARDGRPIVICNEGDAIISNDKVHTTLEVPETVDCLQGLLNVIPLQLISYWLAVNRGIDVDFPRNLAKSVTVE
Protein: Histone H2A type 1-C (H2A-clustered histone 6) (Histone H2A/l) (Q93077)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H2B type 1-D
- Histone H2B type 2-E
- Histone H2B type 1-K
- Histone H4
- Histone H2B type 1-H
- Histone H2B type 1-O
- Histone H2B type 1-C/E/F/G/I
- Histone H2B type 1-M
- Histone H2B type 1-J
- Histone H2B type 1-N
Sequence:
MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
Protein: Styrene-oxide isomerase (EC 5.3.99.7) (O06836)
Organism: Pseudomonas fluorescens
Function: Epoxystyrene isomerase that catalyzes the second step in the aerobic styrene degradation pathway by converting epoxystyrene to phenylacetaldehyde.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLHAFERKMAGHGILMIFCTLLFGVGLWMHLVGGFEIIPGYILEFHVPGSPEGWARAHSGPALNGMMVIAVAFVLPSLGFADKKPHLLGNIIILDGWANVGFYFFSNFSPNRGLTFGPNHFGPGDIFSFLALAPAYLFGVLAMGALAVIGYQALKSVGSRKAVPHATAE
Protein: UPF0619 GPI-anchored membrane protein C1322.10 (O94549)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Golgi apparatus membrane; Lipid-anchor, GPI-anchor. Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
Sequence:
MLARVGTTLFFLANALAAYAVSVTSPTRDTTWQSGQVNTVTWSSVSTDPEEMVIMLVNNAHYPNQNFNLGTVQSSAGSLDTDISISSDLPTDGWQIYFNGATSQNQGSLAQSEQFDFEGSDSTLAASTISGGIYSSTSASSTSSSTATPSSSSTTSSSSSSSSSTPISSSITSSISSSASSSVSSSSASSSGSISSADAKTVSASSNSTISGFSTSTTSASSSAAGNSSSSSYTSYSGAVSNGVAQLSVAACMGIAALMLIA
Protein: DNA 3'-5' helicase (EC 5.6.2.4) (A0A8I6AI75)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MKKQLNSISEEMRDLANHFPVTCRNLETLQRVPMILENISENLCSLRKVICASTDTGTKLEPGGGSHLLSSEGSAAVGEKEKQMGEHRTFPKIKEEAWDPELDSLVKHEAVDVFRKQVKQEKGGFEDEMEDSLLREVMERTCLMPSISEYDLQDLEQQAKEEKHNAISHQFSEHLSPDDDEKDSSYIIESDEDLEMEMLKSLENLNSDVGEPTHSKWLETGGSVNLPPEEEDGDGKEAFEEEQEEEDHLLPEPNAKQINCLKTYFGHCSFKPVQWKVIHSVLEERRDNVVVMATGYGKSLCFQYPPVYTGKIGIVISPLISLMEDQVLQLEMSNIPACLLGSAQPKNILGDIKLGRYRIIYITPEFCSGNLDLLQQLDSNIGITLIAVDEAHCISEWGHDFRSSFRTLGSLKTALPLVPVIALSATASSSIREDIIRCLNLKDPHITCTGFDRPNLYLEVERKTGNILQDLKPFLVRKTSSAWEFEGPTIIYCPSRKVTEQVTVELGKLNVACQAYHAGMKISERKDIHHRFLRDEIQCVVATIAFGMGINKADIRKVIHYGAPKEMESYYQEIGRAGRDGLQSSCHLLWAPADFNTTRNRLIEIHNEKFRLHKLKMMVKMEKYLHSSRCRRQIILSHFEDKRLQKASLAVMGTEKCCDNCRPRLNHCSSANNSEDTAQDFGPQAFQLLSAVDILQEKFGIKIPILFLRGSNSQRLPEKYHNHRLFGAGKEQAESWWKALSHHLIAEGFLVEVPKQNKFIKTCSLTKKGRKWLGEAILQSPPSLVLQADEEAFSRKALLSSSNPVSSETKPHSSNQKPTGSSTQQSNLEGAYSDKVPEKFSSGSNIPKKSVVMQSPGTSYSSWEPVISAQEVDTRTVLYARLVEARQKHANEVDVPPAVLATNKVLLDMAKMRPTTVENVKQIDGVSEGKAALLAPLTEVIKHFCQVNSVQTDLFASTKPQEDEEKSQEMENKACSLPQSAAVTYALFQEKKMSLHSIAENRLLPLTAVGMHLAQAVKAGHPLDMERAGLTPETRKIIMDVIRNPPINSDMYKVKLIRMLVPENIDTYLIHMMIEILESGSHGRTQPSCDSNRKRCLPSPAESCGSFKKSKEMVTETKAPSEMSQRKLPEWFVKGNVPLAATGSSSMAKTKKKGLFS
Protein: Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog) (O95639)
Organism: Homo sapiens (Human)
Function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
Subcellular location: Nucleus.
Interaction partners:
- Cleavage and polyadenylation specificity factor subunit 3
- Pre-mRNA 3'-end-processing factor FIP1
- Symplekin
- pre-mRNA 3' end processing protein WDR33
- Cleavage and polyadenylation specificity factor subunit 1
- Cleavage and polyadenylation specificity factor subunit 2
- Cleavage stimulation factor subunit 2
- Cleavage stimulation factor subunit 3
- Cleavage and polyadenylation specificity factor subunit 5
- Cleavage and polyadenylation specificity factor subunit 7
Sequence:
MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ
Protein: Hydroxyacylglutathione hydrolase GloB (EC 3.1.2.6) (Glyoxalase II) (Glx II) (P0AC84)
Organism: Escherichia coli (strain K12)
Function: Type II glyoxalase that catalyzes the hydrolysis of (R)-S-lactoylglutathione to (R)-lactate and glutathione. Is more efficient than the isozyme GloC, and plays a major contribution to methylglyoxal (MG) detoxification in E.coli. The two isoenzymes have additive effects and ensure maximal MG degradation.
Interaction partners:
- Lactoylglutathione lyase
- Protein/nucleic acid deglycase 1
- Hydroxyacylglutathione hydrolase GloC
- D-lactate dehydrogenase
- Quinone-dependent D-lactate dehydrogenase
- Uncharacterized protein YafS
- Methylglyoxal synthase
- 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD
Sequence:
MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
Protein: Peptide chain release factor APG3, chloroplastic (Chloroplast ribosome release factor 1) (AtcpRF1) (Protein ALBINO AND PALE GREEN 3) (Q8RX79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May direct the termination of translation in response to the peptide chain termination codon UAG. Required for normal chloroplast development and plays essential roles in the termination of translation in plastids.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:17450416}.
Interaction partners:
- At5g64156
- AT3g13440/MRP15_7
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- 50S ribosomal protein L33
- Large ribosomal subunit protein bL31c
- At4g25020
- Large ribosomal subunit protein uL3c
- At1g63720/F24D7_9
- Sec-independent protein translocase protein TATC, chloroplastic
- Large ribosomal subunit protein bL27c
Sequence:
MNSSMTTSPTARAFLHLHSSPFTLRSRKSPSGVCLVSWPPSRSRRTRRLVCMAEPYLIRKMESVEKTWKELSVKLADPDVVSNQSEYQKLAQSMSELDEVVTVFRRFKDCEKQLLESKVLAKEAGDDEDMAEMIGSEINSLTKEIEELEKQLKVLLLPSDPLDARNILLEVRAGTGGDEAAIWTGDLVRMYQRYSERSSWKFSMVSCSEAEHGGYKTCVMEIKGNRVYSKLKYESGVHRVQRVPQTETQGRVHTSTATVAIMPEADEVEVVIDPKDIELTSARSGGAGGQNVNKVETAIDLFHKPSGIRIFCTEERTQIRNKARAFQLLRAKLYEIKVREQQEKIRNERKSQVGTGARSEKIRTYNYKDSRVTDHRLKMNFALTTFLDGALEDAVQACAALEQKELMEELSESVAASSATSG