wanglab/gogpt-training-data huggingface dataset:
Protein: Spectrin beta chain (Q9U9J8)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYHDQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKERRKRLEETLELYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDDADITHSSLEGHRKSSHEKRLAHSESSSWRKSLARAPKFDSKDPKGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPAEGSATKKKGGFFSRGKK
Protein: Neurexin-1-beta (Neurexin I-beta) (Q28142)
Organism: Bos taurus (Bovine)
Function: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity).
Subcellular location: Presynaptic cell membrane {ECO:0000250|UniProtKB:P0DI97}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Neurexin-1
- Neuroligin 1
- Neurexin 3
- LRRTM2 protein
- Neuroligin 3
- Neuroligin 2
- Neurexin 3
- Carboxylesterase type B domain-containing protein
- Cerebellin-1
- Synaptotagmin-1
Sequence:
MYQRMLRCGAELGSPGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGNSPTKEPVSQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV
Protein: Nuclear transcription factor Y subunit nfyb-1 (CAAT box DNA-binding protein subunit nfyb-1) (O17286)
Organism: Caenorhabditis elegans
Function: Component of sequence-specific heterotrimeric transcription factor (nfya-1-NF-Y and nfya-2-NF-Y) complexes which specifically recognize a 5'-CCAAT-3' box motif found in the promoters of its target genes to regulate their expression and control cellular identity in particular tissue types. In association with the components in the NF-Y complexes, represses the expression of the T-box transcription factor tbx-2 throughout larval development, which most likely restricts its expression to certain tissues. May act to repress txb-2 expression in conjunction with tbx-2 itself, which has an autoregulatory role. In association with the components in the nfya-1-NF-Y complex, negatively regulates the expression of the homeobox protein egl-5 to spatially restrict its expression in tissues such as the head. May regulate spatial egl-5 expression in association with the mes-2-mes-3-mes-6 complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:17574230}. Cytoplasm {ECO:0000269|PubMed:15704008, ECO:0000269|PubMed:17574230}. Perikaryon {ECO:0000269|PubMed:15704008}. Note=Localizes to the cytoplasm of secretory cells and cell bodies of the small ganglia surrounding the pharynx. {ECO:0000269|PubMed:15704008}.
Interaction partners:
- Nuclear transcription factor Y subunit nfyc-1
- Nuclear transcription factor Y subunit nfya-2
- Nuclear transcription factor Y subunit nfya-1
- RNA polymerase I associated factor, A49-like protein
- T-box protein 2
- Beta'-coat protein
- C2H2-type domain-containing protein
Sequence:
MDPKPINEGMLLEDHDHGMPEEEEITEDDMNGIHNIEEDTRTISEIAMELHHPNKSQVLLDQERFLPIANVVRIMKTQMDPQAKLAKDAKECAQECVSEFISFIASEAAEICNITKRKTITADDLLTAMEATGFDNYAEPMRIFLQKYRQAHKITGPIHRTHPDYVRPPQFQMDPFVRPLFFDTEQGRRCTETQYVINGSEIVKNAPLGEEWNEQTGTLNTRADGYYMEEPMEPMPMEEVEIEEHEEIIEQDSLGAIALEQQGQMQIYVDPKTKQHFAAKETPNGMELYPLIIQDTPLQLENVSGPNQFVMNMPDGRAIPHGMGQEEPQPVSSSSVMRKIGQNPSSYAQQHHHVSHVEQHDDVEYEEEEEVDQVEEDTVPVPIAPRPAATRVQPKRTPTKRKK
Protein: Trafficking protein particle complex subunit 10 (Epilepsy holoprosencephaly candidate 1 protein) (EHOC-1) (Protein GT334) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1) (P48553)
Organism: Homo sapiens (Human)
Function: Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether.
Subcellular location: Golgi apparatus, cis-Golgi network {ECO:0000250}.
Interaction partners:
- Trafficking protein particle complex subunit 2
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit 9
- Trafficking protein particle complex subunit 2-like protein
- Trafficking protein particle complex subunit 1
- Trafficking protein particle complex subunit 4
- Trafficking protein particle complex subunit 3
- Trafficking protein particle complex subunit 8
- Trafficking protein particle complex subunit 6A
- Trafficking protein particle complex subunit 3-like protein
Sequence:
MDASEEPLPPVIYTMENKPIVTCAGDQNLFTSVYPTLSQQLPREPMEWRRSYGRAPKMIHLESNFVQFKEELLPKEGNKALLTFPFLHIYWTECCDTEVYKATVKDDLTKWQNVLKAHSSVDWLIVIVENDAKKKNKTNILPRTSIVDKIRNDFCNKQSDRCVVLSDPLKDSSRTQESWNAFLTKLRTLLLMSFTKNLGKFEDDMRTLREKRTEPGWSFCEYFMVQEELAFVFEMLQQFEDALVQYDELDALFSQYVVNFGAGDGANWLTFFCQPVKSWNGLILRKPIDMEKRESIQRREATLLDLRSYLFSRQCTLLLFLQRPWEVAQRALELLHNCVQELKLLEVSVPPGALDCWVFLSCLEVLQRIEGCCDRAQIDSNIAHTVGLWSYATEKLKSLGYLCGLVSEKGPNSEDLNRTVDLLAGLGAERPETANTAQSPYKKLKEALSSVEAFEKHYLDLSHATIEMYTSIGRIRSAKFVGKDLAEFYMRKKAPQKAEIYLQGALKNYLAEGWALPITHTRKQLAECQKHLGQIENYLQTSSLLASDHHLTEEERKHFCQEILDFASQPSDSPGHKIVLPMHSFAQLRDLHFDPSNAVVHVGGVLCVEITMYSQMPVPVHVEQIVVNVHFSIEKNSYRKTAEWLTKHKTSNGIINFPPETAPFPVSQNSLPALELYEMFERSPSDNSLNTTGIICRNVHMLLRRQESSSSLEMPSGVALEEGAHVLRCSHVTLEPGANQITFRTQAKEPGTYTLRQLCASVGSVWFVLPHIYPIVQYDVYSQEPQLHVEPLADSLLAGIPQRVKFTVTTGHYTIKNGDSLQLSNAEAMLILCQAESRAVVYSNTREQSSEAALRIQSSDKVTSISLPVAPAYHVIEFELEVLSLPSAPALGGESDMLGMAEPHRKHKDKQRTGRCMVTTDHKVSIDCPWSIYSTVIALTFSVPFRTTHSLLSSGTRKYVQVCVQNLSELDFQLSDSYLVDTGDSTDLQLVPLNTQSQQPIYSKQSVFFVWELKWTEEPPPSLHCRFSVGFSPASEEQLSISLKPYTYEFKVENFFTLYNVKAEIFPPSGMEYCRTGSLCSLEVLITRLSDLLEVDKDEALTESDEHFSTKLMYEVVDNSSNWAVCGKSCGVISMPVAARATHRVHMEVMPLFAGYLPLPDVRLFKYLPHHSAHSSQLDADSWIENDSLSVDKHGDDQPDSSSLKSRGSVHSACSSEHKGLPMPRLQALPAGQVFNSSSGTQVLVIPSQDDHVLEVSVT
Protein: Dynein light chain Tctex-type protein 2 (LC2) (T-complex testis-specific protein 2) (T-complex testis-specific protein 3) (T-complex-associated testis-expressed protein 3) (Tcte-3) (T-complex-associated testis-expressed protein 4) (TCTEX-4) (TCTEX-2) (Tctex1 domain-containing protein 3) (P11985)
Organism: Mus musculus (Mouse)
Function: May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305|PubMed:7601308}. Cytoplasmic granule {ECO:0000269|PubMed:7601308}. Membrane {ECO:0000269|PubMed:7601308}; Peripheral membrane protein {ECO:0000269|PubMed:7601308}. Note=Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis.
Interaction partners:
- Dynein light chain roadblock-type 2
- Dynein light chain roadblock-type 1
- Dynein light chain Tctex-type 1
- Dynein light chain Tctex-type 2A1
- Dynein light chain
- Dynein light chain Tctex-type 3
- Cytoplasmic dynein 1 intermediate chain 1
- Dynein light chain 2, cytoplasmic
- Cytoplasmic dynein 2 light intermediate chain 1
- Cytoplasmic dynein 2 intermediate chain 2
Sequence:
MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKDSLKDVKYDDKAPHLSLELADGILAAVKEFAYHRYKFIIQVLFIQKTGQAINIASRWIWDVAWDNWVEAKHETESYVVLALVFALYCE
Protein: Primosome protein PriB (Q5F924)
Organism: Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Function: Stimulates the DNA unwinding activity of PriA helicase, which does not seem to require single-stranded DNA-binding by PriB. Activates DNA-dependent ATP hydrolysis catalyzed by PriA. Has a weak single-stranded DNA-binding activity. Binds weakly also double-stranded DNA, a partial duplex DNA with a 3' single-stranded DNA overhang, and a forked DNA structure with fully duplex leading and lagging strand arms in vitro.
Interaction partners:
- Small ribosomal subunit protein bS6
- Small ribosomal subunit protein bS18
- Large ribosomal subunit protein bL9
- DNA primase
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL22
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL2
Sequence:
MGFTNLVSLAALIEKAFPIRYTPAGIPVLDIILKHESWQEENGQQCLVQLEIPARILGRQAEEWQYRQGDCATVEGFLAQKSRRSLMPMLRIQNIKEYKG
Protein: Adenylate kinase 4 (EC 2.7.4.3) (ATP-AMP transphosphorylase 4) (ATP:AMP phosphotransferase) (Adenylate kinase B) (AK B) (Adenylate monophosphate kinase 4) (Q08480)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P69441}.
Interaction partners:
- Adenylosuccinate lyase
- Adenosine kinase
- Adenosine kinase
- adenine phosphoribosyltransferase
- Nucleoside diphosphate kinase
- Adenylate kinase isoenzyme 6 homolog
- Nucleoside diphosphate kinase
- Nucleoside diphosphate kinase
- Nucleoside diphosphate kinase 1
- Guanylate kinase 1
Sequence:
MAAAANLEDVPSMDLMNELLRRMKCSSKPDKRLILVGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGVKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFILDGFPRTVVQAQKLDEMLEKKGTKVDKVLNFAIDDSILEERITGRWIHPSSGRSYHTKFAPPKVPGVDDVTGEPLIQRKDDTAEVLKSRLEAFHKQTEPVIDYYSKKALVANLHAEKPPKEVTAEVQKVLS
Protein: Uncharacterized protein C11orf24 (Protein DM4E3) (Q96F05)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000269|PubMed:24312644}; Single-pass type I membrane protein {ECO:0000269|PubMed:24312644}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:24312644}; Single-pass type I membrane protein {ECO:0000269|PubMed:24312644}. Note=Cycles to the plasma membrane via endosomes in a pH sensitive manner. Associated with Rab6-positive vesicles.
Interaction partners:
Sequence:
MWTALVLIWIFSLSLSESHAASNDPRNFVPNKMWKGLVKRNASVETVDNKTSEDVTMAAASPVTLTKGTSAAHLNSMEVTTEDTSRTDVSEPATSGGAADGVTSIAPTAVASSTTAASITTAASSMTVASSAPTTAASSTTVASIAPTTAASSMTAASSTPMTLALPAPTSTSTGRTPSTTATGHPSLSTALAQVPKSSALPRTATLATLATRAQTVATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQAQGPISQVSVDQPVVNTTNKSTPMPSNTTPEPAPTPTVVTTTKAQAREPTASPVPVPHTSPIPEMEAMSPTTQPSPMPYTQRAAGPGTSQAPEQVETEATPGTDSTGPTPRSSGGTKMPATDSCQPSTQGQYMVVTTEPLTQAVVDKTLLLVVLLLGVTLFITVLVLFALQAYESYKKKDYTQVDYLINGMYADSEM
Protein: MICOS complex subunit Mic60 (Mitochondrial inner membrane protein) (Mitofilin) (Q8CAQ8)
Organism: Mus musculus (Mouse)
Function: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q16891}; Single-pass membrane protein {ECO:0000255}. Mitochondrion {ECO:0000250|UniProtKB:Q16891}.
Interaction partners:
- MICOS complex subunit Mic19
- MICOS complex subunit Mic25
- MICOS complex subunit Mic10
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- MICOS complex subunit Mic26
- MICOS complex subunit Mic27
- DnaJ homolog subfamily C member 11
- Sorting and assembly machinery component 50 homolog
- MICOS complex subunit MIC13
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Sequence:
MLRACQLSGVTVAAQSCLCGKFVLRPLRPCRRYSTSSSSGLTAGKIAGAGLLFVGGGIGGTILYAKWDSHFRESVEKTIPYSDKLFGMVLGSAPYTVPLPKKPVQSGPLKISSVSEVMKDSKLPVAQSQKTKGDTPASAASTGAAQIISAAGDTLSVPAPAVQHEDTIKTECPNTNEGKSTSETTEEAFSSSVRERPPEEVAARLAQQEKQEQVEMESLAKSLEDALNRTSSVTLQTITAQNAAVQAVKAHSNILKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPHITAAEGRLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGKLSTDDLNSLIAHAHRRIDQLNRELAQQKATEKQHIELALEKHKLEEKRTFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKYEFEQGLSEKLSEQELEFRRRSQEQMDSFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIPLGSAVEAIRVNCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQLKPPAELYPEDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGTTQVQQE
Protein: NAD(P)H oxidoreductase RTN4IP1, mitochondrial (EC 1.6.5.-) (Reticulon-4-interacting protein 1 homolog) (Q7T3C7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in the regulation of retinal ganglion cell (RGC) maturation, neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:Q8WWV3}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8WWV3}. Note=Mainly localizes to the mitochondrial matrix. {ECO:0000250|UniProtKB:Q8WWV3}.
Interaction partners:
- Transmembrane protein 126A
- Carbonyl reductase 1-like
- 40S ribosomal protein S27
- ATP synthase lipid-binding protein
- von Willebrand factor A domain-containing protein 8
- Tetraspanin
Sequence:
MLMCRRWLVCSLRCHYRSFSFSAARRTVMPAWVIDKYGKNDVLRFTKNAALPIIHYPNEVVVKVHAAGLNPIDISMRGGYGAATMAMKRDPLNISQSGGEFPLILGRDVSGEIMECGLDVKYFKPGDQVWAAIPPWKQGSLAEFVVVSGNEVSHKPKSLRHDEAASIPYVAATAWSAIVNTGGLNKDNSAKKRVLILGGSGGVGTFAIQMVKAWGAHVTVTCSQNAERLVRDLGADDVVDYTAGPVEKQLKNLEKFDLILDSIGGETEKWALDLLKPWSGAKFVTLITPFLQNTDRLGLADGMMQSAVTVGCKVVKNLRKGVHYRWGFFAPSGSALDEVSEMVDAGKVRPVVEEVFSFAQVPEAFQKVEQGHARGKTVVSIMEDQKE
Protein: High mobility group protein B2 (Q8IB14)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- FACT complex subunit
- Tetratricopeptide repeat protein, putative
- Transcription elongation factor SPT6, putative
- Histone H4
- CDC73 domain-containing protein, putative
- Transcription elongation factor SPT4, putative
- DNA-directed RNA polymerase II subunit RPB3, putative
- DNA helicase
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase II 16 kDa subunit, putative
Sequence:
MASKSQKKVLKKQNKKKKKDPLAPKRALSAYMFYVKDKRLEIIKEKPELAKDVAQVGKLIGEAWGQLSPAQKAPYEKKAQLDKVRYSKEIEEYRKKNQE
Protein: Alpha-1,3/1,6-mannosyltransferase alg2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) (Q96WW6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P43636}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Chitobiosyldiphosphodolichol beta-mannosyltransferase
- GDP-Man:Man
- Crossover junction endonuclease mus81
- O-glycoside alpha-1,2-mannosyltransferase homolog 5
- Conserved oligomeric Golgi complex subunit 8
- Phospholipid-transporting ATPase accessory subunit ivn1
- Small ribosomal subunit protein uS15m
- Protein bem46
- Phosphomannomutase
Sequence:
MSQENSVHRSSTKKTPIKIAFIHPDLGIGGAERLVVDAAVGLQSLGKEVVVFTSHCDKKHCFEEIRDGTIKVKVYGDWLPSSIFGRLSIFCSSLRQVYLTMILLTNYMHFDAIIVDQLSTCVPFLLLASQMILFYCHFPDKYLAKRGGILKKLYRIPFDTVEAESVRLADRIVVNSKFTASVFKKAFPKIRKPLRIVHPCVDIEAASKPLEFQLPEKILQRKLLISVNRFERKKDIRLAIDAFSALRDLSANRFPEYLLLVAGGYDIRVSENRRYLKELQEFCEQKDLSYTTVKDNWDNITVAPSTNVLFLLSVPSKVRDALISSSRILLYTPENEHFGIVPLEAMLRKVPVLAQTNGGPLETVIDGKNGWLRPRDAKIWGNVIYEATTSTTYDTAAMGEAGSEWVKNEFSTDAMARKFESEIMSGIRSITPEKRLMRRVNGLLAVFVLFMLFWGTCIIAATVPFAIIKLYFAQTYSSVKLGFMLGTCIVSVSFLTFTVYAKLTNL
Protein: DNA processing protein DprA (Q8DPI7)
Organism: Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Function: Protein that helps load RecA onto ssDNA during transformation. Required for DNA transformation. Not required for DNA uptake but for a later stage of transformation. Thought to interact at the cell pole with newly imported transforming ssDNA which it binds cooperatively, protecting linear and circular ssDNA from nuclease action. Forms bridges between DNA segments. Favors the loading of RecA onto ssDNA and formation of RecA-DNA filaments, triggering RecA-catalysis of ATP-driven homologous DNA pairing.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P39813}. Note=Localizes to the cell poles during competence (By similarity). {ECO:0000250|UniProtKB:P39813}.
Interaction partners:
- Protein RecA
- Single-stranded DNA-binding protein
- Competence protein ComFC
- Competence protein ComFA
- Single-stranded DNA-binding protein
- Competence protein
- Response regulator
- DNA repair protein RecO
- UPF0758 protein spr0996
- DNA topoisomerase 1
Sequence:
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGKTIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF
Protein: Secretory 31, isoform A (A1Z7J7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
Sequence:
MKIKELQKTVNIAWSPAQQQQILLAAGTAAQQFDSNANSTLELYSPNFSDATYDLELRASVSSQYKFQKLIWSPVGPHPSGLIVGGCEAGQINIYSADKLLAGKEEPLLKRQDKHTGAVSGLDFNPFQNNLLASCASESEILIWDLNNPETSMSPGTKTQPLEDVKNVAWNRQVQHILASVFSTRCVIWDLRKSQQIIKLSDSQSRVRWHAIEWHPEAATQVWLASEDDQAPVVQLWDLRYATAPAKTYQIHERGVLGMSWCLQDNDLMVSCGKDNRIYCWNPNTKIPEGEILSEVATTASWYSDVQFCPRNPALIASASLEGAVSIYSLHGGTHHLVQTANKIADSFPGMDQFAQEPIPQQATQVVYHDLAHAPKWMKRPCGVAFGFGGKLVSFNGTSKTVKVQQLTTESALVDRANALERSLVDANYSDYCRQRADETPDQHGRYIWYFIKANFELNPKEEMLNLLGYNKDDIDSKFNKFIKETDGNSHSDVDTLTTRISTLTHTQDNKFDGNAIDSQNHNDFATPPRPQFKVPSGDHSDSLIAEAILTGNVDAAVELCLEAQRIPEALIIASTAGIETLNRTQTRYLLQQKNELSHVISALVSRDWLDFVNRCTVDSWKEALVAALKHSERKVVDICERLGDRLLSECASSAEFTRNAMLCYICAGSIDKLVTAWYQLKRLEQQNPGYKPNTTELQDLAEMVMLMCKSLEQQGISVDLAGRFAGFLTEYGGLLASQGALTAALQYITTLGGGAAASESDVLQSLRDRINNAVNLDYTQPQAAVAAAPHGYQPTRGRGSFSQPQPSAPMPYGQPPNQYAQPSWPAQVPPLQTSYPGAQQPQAPPQIFNPQPVKPEPLAQPPRPLSNASSSGGPPPAGGASSSGGSGLSGRSKYVLDPSVAAPTSSYGMPYNPVPAPVPSAVPFGGGGVPGPAPQPASVPTYNSNAFNTNPIAAAQPYNPSPLMPAQQNQFVPGVNPIETMPPPAVPPVIQNVQRNPTPPPGWNDPPALKSSRAPKPKPVVEPSAAIFHPLFPVDPNQNQNGYVDPSQYQHAAPLGGVPNTYYNPAAFNNNPQQQQQHQQSYLQPQQPAPGIQQPNWQGQQQTIGYTEQPAPIQQQRQPAPPKEKPPLPEEYIYLQTVLEELKNRCLGATNDPRTKRKFVDVVKRLENLYDCLRDGKLTPTTVQYLNQIVQYIQISDYANAMEIHTQIAFGTDFAQCAGFMQGLKVLLQSASELQLVLR
Protein: Protein RETICULATA-RELATED 2, chloroplastic (Q9C9Z3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in leaf development.
Subcellular location: Plastid, chloroplast membrane {ECO:0000250|UniProtKB:Q9C9Z2}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Dehydrodolichyl diphosphate synthase 6
- Dehydrodolichyl diphosphate synthase 5
- Dehydrodolichyl diphosphate synthase 1
- 3-oxo-5-alpha-steroid 4-dehydrogenase
- Lung seven transmembrane receptor family protein
- Dehydrodolichyl diphosphate synthase 7
- Nuclear transport factor 2
- Dehydrodolichyl diphosphate synthase 8
- NAD-dependent protein deacetylase SRT1
- Dehydrodolichyl diphosphate synthase 2
Sequence:
MAAMAAKLHISTKSDQSNVRLPRLINLSRDPTARVLFPRNGSVSSLHTNFSSPNIMVPCAGGGGGGSIGNHGGGSGSGGGGGGYGGSEEEESSPWGPLGLFIQGWRSRVAADSQFPFKVLMEMLVGVSANVLGDMASRPNFGLNELDFVFSTLVVGSILNFTLMYLLAPSAISHGSSNLLPGIFRSCPSSHMFEQGNFTLMNRFGTLVYKGMVFATVGLAAGLVGTAISNGLIMLRKKIDPSFETPNKPPPTLLNSLTWATHMGVSANVRYQTLNGAEFLLEKSLPPLVFKTSVIALRVVNNVLGGMSFVTLARMTGSQSVEEEKKIEMSEISEKEKED
Protein: Complement C5 [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain] (P08650)
Organism: Rattus norvegicus (Rat)
Function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Subcellular location: Secreted {ECO:0000269|PubMed:7987212}.
Interaction partners:
- Complement component C9
- C5a anaphylatoxin chemotactic receptor 1
- Complement component C8 beta chain
- Complement component C6
- Complement C7.
- C5a anaphylatoxin chemotactic receptor 2
- Complement C8 alpha chain
- Complement component C8 gamma chain
- Complement C3
- C3a anaphylatoxin chemotactic receptor
Sequence:
MGLWGLLCLLIFLDKTWGQEQTYVISAPKIFRVGSSENVVIQAHGYTEAFDATISLKSYPDKKVTYSSGYVNLSPENKFQNSALLTLPPKQFPRDENPVSHVYLEVVSMHFSKSKKIPITYDNGFLFIHTDKPVYTPDQSVKIRVYSLSDDLKPAKRETVLTFVDPEGTEVDIVEENDYTGIISFPDFKIPSNPKYGVWTIKAKYKKDFTTTGTAYFEVKEYVLPRFSVSIEPESNFIGYKNFKNFEITVKARYFYNKMVPDAEVYIFFGLREDIKEDEKQMMHKAMQAATLMDGAAQTCWLAETEVREINYNMFEDRNNNYSYIACTVTESSGGFSEEAEIPGIKYVLSPYTLNLVATPLFLKPGIPFSIKVQVKDSLEQLVGGVPVTLMAQTVNVNQETSDLEPKRSITHSADGVASFVVNLPSEVTSLKFEVKTDAPELPEENQASKEYEAVTYSSLSQSYIYIGWTENYKPMLVGEYLNIIVTPKSPYIDKITHYNYLILSKGKIVQYGTKEKLLYSSYQNINIPVTQDMVPSARLLVYYIVTGEQTAELVADAVWINIEEKCGNQLQVHLSPDKDVYSPGQTVSLDMVTEADSWVALSAVDSAVYGVRGKAKRAMQRVFQAFDDKSDLGCGAGGGRDNVDVFHLAGLTFLTNANADDSQYHDDSCKEILRPKRDLQLLHQKVEEQAAKYKHRVPKKCCYDGARENKYETCEQRVARVTIGPHCIRAFNECCTIADKIRKESHHKGMLLGRIQIKALLPVMKAEIRSYFPESWLWEVHRVPKRNQLQVALPDSLTTWEIQGIGISDNGICVADTLKAKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGTMFCVKMSAVEGICTPGSSAASPQTSRSSRCVRQRIEGSSSHLVTFSLLPLEIGLHSINFSLETSFGKEILVKTLRVVPEGIKRESYAGVTLDPRGVYGIVNRRKEFPYRIPLDLVPKTNVKRILSVKGLLIGEFLSTVLSKEGIDILTHLPKGSAEAELMSIVPVFYVFHYLEAGNHWNIFHPDTLARKQSLQKKIKEGLVSVMSYRNADYSYSMWKGASSSAWLTAFALRVLGQVNKYVKQDQYSICNSLLWLIEKCQLENGSFKENSQYLPIKLQGTLPAEAQENTLYLTAFSVIGIRKAIGICPTEKIYTALAKADSFLLERTLPSKSTFTLAIVAYALSLGDRTHPKFRSIVSALKREALVKGDPPIYRFWRDTLQRPDSSAPNSGTAGMVETTAYALLTSLNLKETSYVNPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLHLDMDINVSYKHKGDFYQYKVTEKNFLGRPVEVPLNDDLIVTTGYSSGLATVYVKTVVHKTSVAEEFCSFYLKIDTQEVEASSYLSYSDSGHKRIIACASYKPSKEESASGSSHAVMDILLPTGIGANQEDLRALVEGVDQLLTDYQIKDSHVILQLNSIPSRDFLCVRFRIFELFQVGFLNPATFTVYEYHRPDKQCTMIYSTSDTNLQRVCEGAACKCVEADCGQLQAELDLAISADTRKETACKPEIAYAYKVRITSATEENIFVKYTATLLDIYKTGEAAAEKDSEITFIKKISCTNANLVKGKQYLIMGKEALQIKHNFSFKYIYPLDSSTWIEYWPTDTTCPSCQAFVANLDEFAEDIFLNGCE