wanglab/gogpt-training-data huggingface dataset:
Protein: GPI transamidase component Gpi16 subunit family protein (Q949U5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Peptidase C13 family
- GPI transamidase component PIG-S-like protein
- GPI transamidase component family protein / Gaa1-like family protein
- GPI transamidase subunit PIG-U
- GPI transamidase subunit PIG-U
- GPI inositol-deacylase
- Uncharacterized protein
- GPI ethanolamine phosphate transferase 3
- At1g16040
- Arogenate dehydrogenase 2, chloroplastic
Sequence:
MASLLRSLILLLIVQSFLVAIAFGSKEVEEFSEALLLKPLPDRKVLAHFHFENRAPPSNSHGRHHHLFPKAISQLVQKFRVKEMELSFTQGRWNHEHWGGFDPLSSMNAKPVGVELWAVFDVPQSQVDTSWKNLTHALSGLFCASINFLESSTSYAAPTWGFGPNSDKLRYGSLPREAVCTENLTPWLKLLPCRDKDGISALMNRPSVYRGFYHSQRLHLSTVESGQEGLGSGIVLEQTLTVVLQPETTSVESNMQPSWSLSSLFGRQVVGRCVLAKSSNVYLQLEGLLGYESKNVDTEIEAHQLWKNAEFELSLKPERVIRESCSFLFIFDIDKSSDSEPFDLGLTWKRPSKWSCQQAPLHSSRFLMGSGNERGAIAILLKATESQEKLSGRDLTNGQCTIKANIFQIFPWYIKVYYHTLQIFVDQQQKTDSEVLKKINVSPSTDKVSSGMMEMMLELPCEVKSVAISIEYDKGFLHIDEYPPDANQGFDIPSALISFPDHHASLDFQEELSNSPLLSSLKEKSLVRSYTEVLLVPLTTPDFSMPYNVITITCTIFALYFGSLLNVLRRRIGEEERFLKSQAGKKTGGLKQLLSRITAKIRGRPIEAPSSSEAESSVLSSKLILKIILVAGAAAAWQYFSTDE
Protein: Acyl-CoA thioesterase 13 (Acyl-coenzyme A thioesterase 13 isoform X1) (F6P1Y9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- UbiA prenyltransferase domain-containing protein 1
- Tyrosyl-DNA phosphodiesterase 2
- Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
- Malonyl CoA:ACP acyltransferase
Sequence:
MLESVMASLTLNTVKQIFRAMADSPGFDRVLSKVEVLSAAPGKVVCEMKVEEQHTNRGGTLHGGMTATLVDMISTMAIMYSERGAPGVSVDMNITYMNAAKIGEDILITAQVLKQGRTLAFATVDLTNKANGKLIAQGRHTKHLGS
Protein: PHLDA1 protein (A2BDE7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
LCLLRVSLLCALRAGGRGSRWGEDGARLLLLPPARAAGNGEAEPSGGPSYAGRMLESSGCKALKEGVLEKRSDGLLQLWKKKCCILTEEGLLLIPPKQLQHQQQQQQQQQQQQQQPGQGPAEPSQPSGPAVASLEPPVKLKELHFSNMKTVDCVERKGKYMYFTVVMAEGKEIDFRCPQDQGWNAEITLQMVQYKNRQAILAVKSTRQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPHGHRLLRSTSNSA
Protein: Beta-2-microglobulin (Q91203)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKYILSIVVLGLIYSVVEAKESPPKVQVYSRNPGNFGDKNTLICHVSGFHPPDISIQLLKNGVEIPDAKQTDLAFEQGWQFHLTKSVGFTPASGEEYTCRVRHLKNLKTYTWEADM
Protein: 26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5) (Q9UNM6)
Organism: Homo sapiens (Human)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Interaction partners:
- Proteasome subunit beta type-4
- 26S proteasome non-ATPase regulatory subunit 6
- Proteasome subunit beta type-7
- Proteasome subunit alpha type-1
- Proteasomal ubiquitin receptor ADRM1
- 26S proteasome regulatory subunit 6A
- 26S proteasome regulatory subunit 6B
- 26S proteasome regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome non-ATPase regulatory subunit 3
Sequence:
MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQAHDILT
Protein: H/ACA ribonucleoprotein complex non-core subunit NAF1 (Nuclear assembly factor 1) (O14360)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by GAR1 to yield mature H/ACA snoRNPs complex (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P53919}. Note=Absent from the nucleolus. {ECO:0000250|UniProtKB:P53919}.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit cbf5
- H/ACA ribonucleoprotein complex subunit nhp2
- H/ACA ribonucleoprotein complex subunit nop10
- Protein shq1
- tRNA pseudouridine synthase 4
- H/ACA ribonucleoprotein complex subunit gar1
- 13 kDa ribonucleoprotein-associated protein
- U3 small nucleolar ribonucleoprotein protein mpp10
- Brix domain-containing protein C4F8.04
- Uncharacterized protein C18B11.06
Sequence:
MYPHLPCKIPGLSLIYDDESKVEKSKQLSTNASSSNFVKEDQIPSNLSIDNINTPQGDPIDKNNLNTNTENNLPNIVNFQNISSANSGEIKQKDNEILFSSTEDINQHKENYQDENKIDLLDVALANPKDCVVPSSGLLMPKEEFISNEEVGIPATNSSEKSNVKIADEIAEVTHSNSSIGKSSADLSSDSSSDSESNTSFSETDVEEEKAEEKSDAESMAPSTPPKTVNELPEQIYEKPEIVLQPNSLIEPLGKIIQVLKREVVVKSDIDDEKIVFDEKTVLCFEDRSIIGYIHETFGPVSSPYYIVRFSTEEECSAINACMGRPVFYVPTMANKIDPEPLKYIKGSDASNVYDEEINPSEQEFSDDEAEVAAKQLKKKRKRKAKSMVSGNQALPGEANFQSLNQNNVRNYPFYQTNQGSNPPAKRFTQEPPSSSLYSLSESSINYSTQSPMYYNYNYPQPSFPPFHPIYNDSIGYYSQANPQMYYANQVSAPPPQGSFDPNSKFYRNSSDSYRK
Protein: DSC E3 ubiquitin ligase complex subunit 2 (EC 2.3.2.27) (Defective for SREBP cleavage protein 2) (RING-type E3 ubiquitin transferase DSC2) (UBA domain-containing protein 14) (Q9UTK7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. The complex also plays an important role in the multivesicular body (MVB) pathway and functions in a post-endoplasmic reticulum pathway for protein degradation.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:21504829}; Multi-pass membrane protein {ECO:0000269|PubMed:21504829}.
Interaction partners:
- DSC E3 ubiquitin ligase complex subunit 3
- DSC E3 ubiquitin ligase complex subunit 4
- DSC E3 ubiquitin ligase complex subunit 1
- UBX domain-containing protein 10
- Ubiquitin fusion degradation protein 1
- Nuclear protein localization protein 4
- ERAD-associated E3 ubiquitin-protein ligase hrd1
- tRNA
- Putative ERAD-associated E3 ubiquitin-protein ligase component
- Ribosome biogenesis protein brx1
Sequence:
MSSANIVPSNMGITKFLLLTISTSSVVAGVFALKPFFHINFGLHLLSHYQYWRILLWQFIYWNSTEVFQALFIIYQARDVERLLGSHRFASFCVYMFILGMFVTPIFSFLYSLLFKNLDYIQPGPTFLIFAILYQYYYIVPSTVFVRLFNIKFTDKFQMVIPMIGLAFSHFPSTFINAFLGWTMGMFYHLSLLPGTSWRLPIRFVKPALSPTHVFIRPPYSDMQNASTFNPETLFALPTGLDAERTENENQVENPVSNADANDSPTRQNARATAIASSSNTAASFRNRQQISHPPLGRTSSSSVLPTGPASQLYDMLSGRSERPELGNIREEDINTVQTIMQTSRAQAIQALSQTNDVQRAVELLLEQTADY
Protein: Vacuolar protein-sorting-associated protein 25 (ESCRT-II complex subunit VPS25) (P47142)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12194858}. Endosome membrane {ECO:0000269|PubMed:12194858}; Peripheral membrane protein {ECO:0000269|PubMed:12194858}.
Interaction partners:
- Vacuolar protein-sorting-associated protein 36
- Vacuolar protein sorting-associated protein 28
- Vacuolar protein sorting-associated protein 20
- DOA4-independent degradation protein 4
- Vacuolar protein-sorting-associated protein 24
- Vacuolar-sorting protein SNF7
- Vacuolar-sorting protein SNF8
- Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease
- Multivesicular body sorting factor 12
- Protein SRN2
Sequence:
MSALPPVYSFPPLYTRQPNSLTRRQQISTWIDIISQYCKTKKIWYMSVDGTVINDNELDSGSTDNDDSKKISKNLFNNEDIQRSVSQVFIDEIWSQMTKEGKCLPIDQSGRRSSNTTTTRYFILWKSLDSWASLILQWFEDSGKLNQVITLYELSEGDETVNWEFHRMPESLLYYCLKPLCDRNRATMLKDENDKVIAIKVV
Protein: Serine/threonine-protein kinase RCK2 (EC 2.7.11.1) (CAM kinase-like protein kinase CLK1) (P38623)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Serine/threonine-protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Vacuolar protein sorting-associated protein 41
- Mitogen-activated protein kinase HOG1
- Meiosis-specific serine/threonine-protein kinase MEK1
- MAP kinase kinase PBS2
- Protein STE50
- CRE-binding bZIP protein SKO1
Sequence:
MLKIKALFSKKKPDQADLSQESKKPFKGKTRSSGTNNKDVSQITSSPKKSFQDKNIVQYPSVVADDHHMKSLTDELVTTIDSDSSPSDNITTENVETVTSVPAIDVHESSEGQLSSDPLISDESLSEQSEIISDIQDDSTDDDNMEDEIPEKSFLEQKELIGYKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQKKAGTSERRHPHKKQFQLFQRDSSLLFSPAAVAMRDAFDIGNAVKRTEEDRMGTRGGLGSLAEDEELEDSYSGAQGDEQLEQNMFQLTLDTSTILQRRKKVQENDVGPTIPISATIRE
Protein: Inorganic pyrophosphatase (PPA) (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase) (D4GT97)
Organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Function: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions (By similarity). The hydrolysis of PPi by inorganic pyrophosphatase releases a considerable amount of energy that can drive unfavorable biochemical transformations to completion (Probable). Is not active on nucleoside triphosphates (ATP, TTP, GTP, or CTP) or nucleoside diphosphate (ADP).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00209}.
Interaction partners:
- A-type ATP synthase subunit K
- A-type ATP synthase subunit A
- A-type ATP synthase subunit D
- A-type ATP synthase subunit B
- NADH-quinone oxidoreductase subunit C/D
- NADH dehydrogenase-like complex subunit CD
- Polyphosphate-dependent ADP phosphorylase
- A-type ATP synthase subunit I
- Polyphosphate kinase
- Polyphosphate kinase
Sequence:
MVNLWEDMETGPNAPDEIYAVVECLKGERNKYEYDKDIPGVVLDRVLHSNVHYPSDYGFIPQTYYDDEDPFDVLVLVEDQTFPGCVIEARPVALMKMDDDGEQDDKVIAVPVEDPRYDHIEDLDDIPQQTLDEIDEFFATYKNLEAGKEVETLGWEDKQAAKDAIEHAMDLYEENFA
Protein: Histone-binding protein MSI1 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor 1 subunit p50) (CAF-1 p50 subunit) (IRA1 multicopy suppressor) (P13712)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro. It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. p50 and p60 form complexes with newly synthesized histones H3 and acetylated H4 in cell extracts (By similarity). Independently, MSI1 is involved in regulation of the RAS/cAMP pathway via sequestration of NPR1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11238915}. Nucleus {ECO:0000269|PubMed:11238915}.
Interaction partners:
- Chromatin assembly factor 1 subunit B
- Chromatin assembly factor 1 subunit A
- Histone chaperone RTT106
- Histone chaperone ASF1
- Histone H3
- Histone H4
- Protein HIR2
- Histone deacetylase RPD3
- Chromatin modification-related protein EAF3
- Protein HIR1
Sequence:
MNQCAKDITHEASSIPIDLQERYSHWKKNTKLLYDYLNTNSTKWPSLTCQFFPDLDTTSDEHRILLSSFTSSQKPEDETIYISKISTLGHIKWSSLNNFDMDEMEFKPENSTRFPSKHLVNDISIFFPNGECNRARYLPQNPDIIAGASSDGAIYIFDRTKHGSTRIRQSKISHPFETKLFGSHGVIQDVEAMDTSSADINEATSLAWNLQQEALLLSSHSNGQVQVWDIKQYSHENPIIDLPLVSINSDGTAVNDVTWMPTHDSLFAACTEGNAVSLLDLRTKKEKLQSNREKHDGGVNSCRFNYKNSLILASADSNGRLNLWDIRNMNKSPIATMEHGTSVSTLEWSPNFDTVLATAGQEDGLVKLWDTSCEETIFTHGGHMLGVNDISWDAHDPWLMCSVANDNSVHIWKPAGNLVGHS
Protein: Cellobiose dehydrogenase (EC 1.1.99.18) (E7D6C3)
Organism: Hypoxylon haematostroma
Interaction partners:
Sequence:
MPSFSRIATAVLAAATTLRTCLAQEPTPYKDPETGIEFGTWVQGDQTIGLTLPEDALTKDANEYIGYLKCAKGWCGVSHGQSGQMTQALLIVAWPHEGQVLTSFRFTSGYTFPDVYAGDATITQISSKVTDTGFELIYRCQNCFSWDHEGSTGSVSSSGGFFILGHASANTVPSNPQCPAEIRFGQHQRFGQFGAPLAGLARAEYPTWAALATKEVKGECDDTNPPGPTDPVPACNKAMIGQTFDYIVVGAGAGGIPIADRLSEKGHRVLLVEKGPPSTGRWGGSLKPLWLEKTDLTRFDVPGLCNQIWVDSDGIACTDTDQMAGCVLGGGTAVNAGLWWKANPKDWDENFPRGWKNSDLRAATDRTFKRIPGTTRPSQDGELYMHQGFDVIANGLEKAGWKNLPNPNNAPTQKNHTFGSTTYMFAGGERGGPLATYLTTAAERANFALWMNTPVRRALRSGSRVTGVELGCTVEGGAFGTVNVTPNTGRVIVSAGTFGSAKFLFRSGIGPNDQLEVVANSASDGKSFIAKDSWINLPVGHNLVDHVNTDTYFTHPDVVFYDFYEAWTDPIEEDKNKYLSKRSGILAQAAPNIGPVFWDEIKGADGVVRQLQWTARVEGEDQTNSSNTMIMSQYLGRGQTSRGRMTIQPSLTTIVSTPPYLRDPNDKAAVIQGIENIRKALSSVTGLEFRLPTADQSTEAYVDGIEVSAAKRRANHWMGTAKLGTDDGRKNGGTAVVDTNTRVYGTDNLFVVDGSIFPGMVTGNPSAMIVAAAEHASDKILALSPRVPAKTPKLTGAQILSL
Protein: coproporphyrinogen oxidase (EC 1.3.3.3) (A2QPN3)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Interaction partners:
Sequence:
MAVPRPYMPLRRSLCQFSSRTCHTPRNLSAPFRRYSSEQKPPSEPKPFTVWRPYLRLAIGVPFIGALVYSMMTEEVTELDSPSLVELDETLKKQATISEQSPMRLRMEKLIKDHQQKIIEELSRIDGKQFKTDTWSRPNGGGGISCVLQDGNVFEKAGVNVSIVYGELPRPAIEKMRADHKSFVGADVDSLSFFAAGLSLVLHPHNPMAPTVHLNYRYFETSDPKDPLNGDKNWWFGGGTDLTPTYLFPEDARHFHQTIKDACDRHDATYYPKFKAWCDKYFYIPHRRECRGVGGIFFDDLDPSFLQSSSTSSQNPQETLFSFVSDGLASFLPSYVPIIERRKDMPFTPEQKEWQQLRRGRYVEFNLVYDRGTSFGLRTPNARIESILMSLPRTASWAYMDPVSGTRTEDSVDGDEALLGEGKEREKEIMDVLKHPRQWV
Protein: 4-sulfomuconolactone hydrolase (EC 3.1.1.92) (4-carboxymethylen-4-sulfo-but-2-en-olide hydrolases) (A6XIG6)
Organism: Hydrogenophaga intermedia
Function: Involved in the degradation of 4-sulfocatechol which is a central intermediate in the degradation of substituted sulfonated benzenes. Catalyzes the hydrolytical desulfonation of 4-sulfomuconolactone to yield maleylacetate.
Interaction partners:
Sequence:
MSEQAVEVSPKCLGPQHHINPLRFVMPPGSWDTHFHVFGPTTKYPYSETRKYTPPDSPFEEYVKLMLALGIERGVCVHPNIHGPDNSVTLDAVERSEGRFLAIVKIAPDVTLPQLKEMKKKGACGVRFAFNPEHGSGELDTALFDRVVQWCGELDWCVNLHFASNAIHSLAERLSQLTIPTLIDHFGRVHPTKGVDQPDFKTLVDLMRLPHMWVKLTGADRISRNSPSYQDVVPLARTLVDVAPDRVIWGTDWPHSGYFDVKRMPNDGDLTNLLLDFAPSEEQRRRILVDNPSRLFGQVAKGA
Protein: Calcium-binding protein CML39 (Calmodulin-like protein 39) (Q9SRE7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potential calcium sensor that binds calcium in vitro.
Interaction partners:
- Probable calcium-binding protein CML43
- Probable calcium-binding protein CML14
- Probable calcium-binding protein CML13
- Probable calcium-binding protein CML44
- Probable calcium-binding protein CML47
- Calcium-binding protein CP1
- Probable calcium-binding protein CML48
- Proteasome maturation factor
- Alpha-crystallin domain-containing protein 22.3
- At1g73440
Sequence:
MKNTQRQLSSSFMKFLEEKNRDLEAVFAYMDANRDGRISAEELKKSFKTLGEQMSDEEAEAAVKLSDIDGDGMLDINEFALLIKGNDEFTEEEKKRKIMEAFRMYIADGEDCITPGSLKMMLMKLGESRTTDDCKVMIQAFDLNADGVLSFDEFALMMR
Protein: Transcriptional adapter ADA2a (AtADA2a) (Q9SFD5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the function of some acidic activation domains, which activate transcription from a distant site. The exact mechanism of action is not yet known (By similarity). ADA2 stimulates the acetyltransferase activity of GCN5 on free histones or nucleosomes, probably by opening up the promoter region.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histone acetyltransferase GCN5
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 10
- Ubiquitin C-terminal hydrolase 22
- SAGA-associated factor 11
- Transcription initiation factor TFIID subunit
- Phosphotransferases/inositol or phosphatidylinositol kinase
- Phosphatidylinositol 3-and 4-kinase family protein with FAT domain-containing protein
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 12b
Sequence:
MGRSKLASRPAEEDLNPGKSKRKKISLGPENAAASISTGIEAGNERKPGLYCCNYCDKDLSGLVRFKCAVCMDFDLCVECFSVGVELNRHKNSHPYRVMDNLSFSLVTSDWNADEEILLLEAIATYGFGNWKEVADHVGSKTTTECIKHFNSAYMQSPCFPLPDLSHTIGKSKDELLAMSKDSAVKTEIPAFVRLSPKEELPVSAEIKHEASGKVNEIDPPLSALAGVKKKGNVPQAKDIIKLEAAKQQSDRSVGEKKLRLPGEKVPLVTELYGYNLKREEFEIEHDNDAEQLLADMEFKDSDTDAEREQKLQVLRIYSKRLDERKRRKEFVLERNLLYPDQYEMSLSAEERKIYKSCKVFARFQSKEEHKELIKKVIEEHQILRRIEDLQEARTAGCRTTSDANRFIEEKRKKEAEESMLLRLNHGAPGSIAGKTLKSPRGLPRNLHPFGSDSLPKVTPPRIYSGLDTWDVDGLLGADLLSETEKKMCNETRILPVHYLKMLDILTREIKKGQIKKKSDAYSFFKVEPSKVDRVYDMLVHKGIGDST
Protein: B-related factor 1 (Q6P9Z3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRQCKNCGGSDIDTDPARGSAVCTACGSVLEDNIIVSEVQFVENSGGVSSAVGQFVSADGTSKAPVLGSGFHTSLGKESRAQTLQNGKRQIHNLGSQLQLNQHCLDTAFNFFKMVVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYILGKTFLLLARELCINAPAVDPCLYIPRFAHMLEFGEKTHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTVKEVISVVKVCETTLRKRLTEFEETPTSSLTIDEFMRVDLEKECDPPSFVAGQKKVKMQQLEQELVKKLEEYQGEIDSYRDEIETQLAGSSRTKMKGIYASYAREDDDSLSVTSGLTGDEDAEDEEMEAAAKHLNQEFISQVLNRRDQGGKKDLDGRKNTVPLPNQPKHVPLTALLGPLPSAASLGLTDSIRQCITETTNVEEKSDSGELDLDGIDEEEIEKYILNEIEVEAKTELWMKQNEEYLREQKEKEERIAKEKEQGTYKEKPKKPSKKREPILASTAGEAIEKMLEQKKISSKINYDVLRDLNSKGSASSSTQQAEDVPTSGSGRKRLTRRKKQPNKSNLGLAKPASLMGKRLRPLISSVPKKKRTAAALFTPSMTMMLPPAAPEPPPAPTPPPVLESGPVAYDEPAEEEEEIEEEAEESCVSAMELIGGNEYGCEAVEEEVF
Protein: Erythroid differentiation regulator (O88727)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MPTGRTDARTDGLTPQGRKPAPTAPPHPPQHTGHTRAPRPPRHTRHTRHTRQAGQAHASAGPAAPATQTRTSRRGQDVHPPRSRCMCHRPSPRWTDGRTRARRQRPPVTAAAHSDVTHESTHVEADAVVKMSLPSPQDGRTDSTRCACRRGRQDGAILTEEGARQQGLTAYRNAPPQ
Protein: SWR1-complex protein 4 (O14308)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Protein AF-9 homolog
- Probable chromatin modification-related protein eaf7
- Enhancer of polycomb-like protein 1
- SWR complex protein 2
- SWR1-complex protein 5
- RuvB-like helicase 1
- Helicase swr1
- Chromatin modification-related protein eaf3
- NuA4 acetyltransferase complex subunit Tra2
- Chromatin modification-related protein png1
Sequence:
MTSADIRDVFELPPPEIGNKQKSKTPTERRPEGISRELYSLLGENSAPLAIYQKKFKEKPKVSHKAKNWVRQPFSISSRKDDFTLHHWVLKSEVDSEASYKFEKFNVPLFIIDYTDEEYQNYLKDEDWNKDETDYLFRLCKDYDLRFFVIADRYDNEKYKKHRTLEDLKDRFYSVSRKILLARNPINSMTAAQSSLLNTMEYNKEQEVIRKKYLIGLASRTPEEVAEEEALFIELKRIETSQAKLLSDRDEVLRLLDEQKGDGGIHEYHTSAGMSSLIQDMINSQRTKNKVEEAIVSSSAPSSGVSSVLNTPTRPHALSTPRIRYGPQPTDPQFGITWHEKLHPGTFVRSQKIPAIKASLSQRVSSVMTELGVSSRLIMPTAKNFEKFVELQNSIVSLLELKRKVDRLSQETEIQDKLSRKRSASPDGSESKKHISQ
Protein: Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196) (Q9H5K3)
Organism: Homo sapiens (Human)
Function: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
- Ribitol-5-phosphate transferase FKTN
- Dystroglycan 1
- Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
- Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1
- Ribitol-5-phosphate xylosyltransferase 1
- Beta-1,4-glucuronyltransferase 1
- Protein O-mannosyl-transferase 1
- Protein O-mannosyl-transferase 2
- Ribitol 5-phosphate transferase FKRP
Sequence:
MEKQPQNSRRGLAPREVPPAVGLLLIMALMNTLLYLCLDHFFIAPRQSTVDPTHCPYGHFRIGQMKNCSPWLSCEELRTEVRQLKRVGEGAVKRVFLSEWKEHKVALSQLTSLEMKDDFLHGLQMLKSLQGTHVVTLLGYCEDDNTMLTEYHPLGSLSNLEETLNLSKYQNVNTWQHRLELAMDYVSIINYLHHSPVGTRVMCDSNDLPKTLSQYLLTSNFSILANDLDALPLVNHSSGMLVKCGHRELHGDFVAPEQLWPYGEDVPFHDDLMPSYDEKIDIWKIPDISSFLLGHIEGSDMVRFHLFDIHKACKSQTPSERPTAQDVLETYQKVLDTLRDAMMSQAREML
Protein: Syntabulin (B7Z4D2)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MFAMKVYGAYLLSSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGASSHKPGSSPSSPREKDLLSMLCRNQLSPVNIHPSYAPSSPSSSNSGSYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLHERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADGLSLEEQVTGEGADRELLVGDSIANSTDLFDEIVTATTTESGDLELVHSTPGANVLELLPIVMGQEEGSVVVERAVQTDVVPYSPAISELIQSVLQKLQDPCPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLSPVETPYANVDAEVHANRLMRELDFAACVEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWAFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT
Protein: Growth hormone (Q0QBD4)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLLLAFTLLCLPWTQVVGAFPAMSLFGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF