wanglab/gogpt-training-data huggingface dataset:
Protein: Not1, isoform D (EC 3.1.13.4) (A8DY80)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNVESQLKTPPTHIRNLVKHVNKRNFNESSEQINQFVKEHGLEADRSSLRHLFSVINFSDLVPSVTVQLQAKLLGIQLERQLHSSSFVSNICYAFDQFFASNQKSLKPVAVADLVGQVARLTGINKVCECVFALALTHSSYTELKHSARNNLKGSLSELIDSYLGNKGTGPADSGLREISFDLLQYLLCCLSEYVQPQVEAQFLIKLREEFPRQAVPLVLAPFLYGSTTATIAGAGASETDAEAEATTNSNSSSFEADALNEVGIEDIYDHLSEIIFTNQGKNNIMDTSWINLILEIGYEFTSSVEECKNHLCSRERERAELQSKDVAKIVGLMCRRHSSLLDCNVNLPTPANFWPGQGQGGGSNSSGSSQTQITPQQQNPGSSNNNDGSDGNSSSDKKDKKETTEATQTWKPDVFVQALKEVVPQLNWKDVCMELDHPEFVLKDRIGLELLLTILRLATGSNIFPHPECIYRHWANTEGQLSLIATMLKNPDLFSFADFVFSQPALDVLKTAPDADNKEISSWKSLHLVEVLLSIADKGYYTQVHELFKFPAQNCPDVLFLALLNTSPPMTPLRQDLFNQLIPTFLGNHPNSNVILASAWSSNNFQLRSNIMNAMSEWYLRGNEFDQVKLSRILDLAQDLKALSALLNARSFLFIIDLACLASRREYLKLEKWLTDKIREHGEPFMQAIIKVLHRRCPQVINAKVPEDQLPPKQAQLLPETVTTMINCLQTCINNCMQPEMVEVIMQMTANVAIMANKARAQQQQQPGLVPPPPPTILRGHRGMDLPGGIVPPPPQQPFSGNLNAQMFGPGMDPLTNMSNNLAGLNLSGPNGAFNFGNMLTSPSRLMTPGANPYPLNLMQMPQAPPPPNVGNLGRMLPGGPQQQTPTPTPTAPNPNNPVMADLQIPVSKEVEDEVNSYFQRIYNHQPNPTLSIDEVLDILQRFKESSNRREQEVFLCMLRNLFEEYRFFCQYPEKELQITAQLFGGIIDRNLVPTFVALGLSLRCVLDALRKPDGSKLYYFGVTALDRFRTRLHTYNKYCEHIRSIPHFSDFPPHLIQYVEYGMHGQEPPPQKLIGLSNTIPSAISSGPGTEPIYRNSSMLGNMPAATPGSGPKSNAAVSHATRMKSIANATNIDTLLVANQEEKVTVPPEPVQDKTAFIFNNLSQLNIPQKCDEIKEIMTKEYWPWLAQYLVLKRASMEFNFHTLYYNFLDALKNGEINRFVTKETLRNIKVLLRSDKGVINFSDRSLLKNLGHWLGMMTLGRNRPILQLDLDLKSLLAEAYHKGQQELLFVVPFVAKILESSAKSRIFRSPNPWTMGIMYVLAELHQEPDLKLNLKFEIEVLCKTLNLELAKLRQVIYLKDPNRTHRIEEQMSQPKPKQLEPVASAPALPREQQSPAQPPPPPQQQQPPQQQVPPPPSSADVDAQNAAAMMMAAGGANSTPGSVSSPNLPTDSSQVALPPPEPRYSYVDVNVSNFQLIGQQLVLPPNTPFLHANPGIKHMVVNAVERTITDWLQPIVDRSIRIACATTEQIIRKDFALDADENRMRTAAHQMVRNLAAGMAMITGKDEIARAISQNLHKALLSGLNGMPSMAEIQAAAMQLASENVELVCAFIQKTSAEKAAAEIDRRLSTDFETRKIAREEGNRFVDAQILTYQQERLPEAVRIKVGAAPATLYAVYSEFARSIPGFQQMSDRDIALFVPKPTDLSQPNVFANDDSMVYGELASKMEAFMNTAIGVPTLQIQASKMHMLLNALIATRRLRDQESAFNLLTRAVEGLTEGLVNMHENMEQMKMYQNIHLRILGLLNNSFGAPNTERAVTKCFFDIREEVRYNVEAARALITSHFVNLNQFDGMLRDCMDNGNNYVAISFGIALLERLIMDDRVINIVSDNEFMATVELLGRLTQHRHRYPECIVNAIDTLWSGNFNSSSDYSPFNGNDRYLSGASHYIHSGMHHSCDTDDPPGLQEKTEFLLKDWVALYTQQNQQSTRDARNFGAFVQKMNTYGILKTDDLITRFFRQATHICTDVVYRMFAEPSLPINQAKNKIFQWIDAFVHLIAMLVRHSGEAGNPTTKINLLNKVLGIVLGTLIKDHEMRGVSFQQVGYHRFFMMLFMELCTADVILESLMHSIVSAFAYTYHLLNPSVAPGFCFAWLELISHRVFLGRILVQIPGQKGWPLYAQLLQDLFKYLAPFLRNTELGKPVQLLYKGTLRVLLVLLHDFPEFLCDYHFGFCDTIPPNCVQMRNIILSAFPRNMRLPDPFTPNLKVDMLSDSSNAPKVLSSYIMNIQPANFKKDLDSYLKARAPVTFLSELRGHLQVTSEPGTRYNMALMNALVMYVGTQAIALIRNKNFVPNTSNIAHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCAVLHLFAEANSEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPIYKFWDHDFVHCAPEITKLFESVARSCLAKSNVTQQLNMPVVDGEGQEVATIN
Protein: PLEKHG1 (Pleckstrin homology domain containing, family G (With RhoGef domain) member 1) (Q5JYA6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MELSDSDRPVSFGSTSSSASSRDSHGSFGSRMTLVSNSHMGLFNQDKEVGAIKLELIPARPFSSSELQRDNPATGQQNADEGSERPPRAQWRVDSNGAPKTIADSATSPKLLYVDRVVQEILETERTYVQDLKSIVEDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGPSPNQQNIVQSLREKFQCLSSSSFA
Protein: Protein HOMOLOG OF MAMMALIAN LYST-INTERACTING PROTEIN 5 (Protein EXTENSIN-LIKE) (EXT-LIKE) (Q9SZ15)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). Thought to be a cofactor of SKD1/VPS4, which catalyzes the disassembly of membrane-associated ESCRT-III. Target of pathogen-responsive mitogen-activated protein kinases (MPKs) that plays a critical role in plant basal resistance to Pseudomonas syringae in a SKD1-dependent manner by promoting multivesicular bodies (MVBs) trafficking upon plant infection.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25010425}. Endosome membrane {ECO:0000250|UniProtKB:Q9NP79}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9NP79}. Nucleus {ECO:0000269|PubMed:25010425}. Endosome, multivesicular body {ECO:0000269|PubMed:25010425}. Note=Localized in multivesicular body when associated with SKD1. {ECO:0000269|PubMed:25010425}.
Interaction partners:
- ESCRT-related protein CHMP1A
- Protein SUPPRESSOR OF K
- ESCRT-related protein CHMP1B
- Vacuolar protein sorting-associated protein 60.1
- Vacuolar protein sorting-associated protein 60.2
- Vacuolar protein sorting-associated protein
- GTP cyclohydrolase 1
- Pre-mRNA-splicing factor SPF27 homolog
- Vacuolar protein sorting-associated protein 32 homolog 2
- Transmembrane protein
Sequence:
MSNPNEPARALLPYLQRADELQKHEPLVAYYCRLYAMERGLKIPQSERTKTTNSILMSLINQLEKDKKSLTLSPDDNMHVEGFALSVFAKADKQDRAGRADLGTAKTFYAASIFFEILSQFGPVPPDIEQKHKYAAWKAADIRKAIKEGRKPTPGDPVDDDTDLSIPSSGPSGSYDHSASDTNTTSHHRTELDPPHDSNDDSSHHQFPEVPQHPLPPRFYDNPTNDYPADVPPPPPSSYPSNDHLPPPTGPSDSPYPHPYSHQPYHQDPPKHMPPPQNYSSHEPSPNSLPNFQSYPSFSESSLPSTSPHYPSHYQNPEPYYSSPHSAPAPSSTSFSSAPPPPPYSSNGRINIAPVLDPAPSSAQKYHYDSSYQPGPEKVAEALKAARFAVGALAFDEVSTAVEHLKKSLELLTNPSAGAGH
Protein: Glycine receptor subunit alpha-2 (Glycine receptor strychnine-binding subunit) (P22771)
Organism: Rattus norvegicus (Rat)
Function: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Plays a role in synaptic plasticity. Contributes to the generation of inhibitory postsynaptic currents, and is involved in the down-regulation of neuronal excitability. Plays a role in cellular responses to ethanol.
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q7TNC8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q7TNC8}. Synapse {ECO:0000250|UniProtKB:Q7TNC8}. Cell membrane {ECO:0000269|PubMed:2176511}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P23415}. Cell projection {ECO:0000250|UniProtKB:Q7TNC8}.
Interaction partners:
- Glycine receptor subunit beta
- Glycine receptor subunit alpha-1
Sequence:
MNRQLVNILTALFAFFLGTNHFREAFCKDHDSRSGKHPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFEYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDADAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
Protein: Palmitoyltransferase ZDHHC2 (EC 2.3.1.225) (Acyltransferase ZDHHC2) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 2) (DHHC-2) (Q9JKR5)
Organism: Rattus norvegicus (Rat)
Function: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). In the nervous system, plays a role in long term synaptic potentiation by palmitoylating AKAP5 through which it regulates protein trafficking from the dendritic recycling endosomes to the plasma membrane and controls both structural and functional plasticity at excitatory synapses. In dendrites, mediates the palmitoylation of DLG4 when synaptic activity decreases and induces synaptic clustering of DLG4 and associated AMPA-type glutamate receptors. Also mediates the de novo and turnover palmitoylation of RGS7BP, a shuttle for Gi/o-specific GTPase-activating proteins/GAPs, promoting its localization to the plasma membrane in response to the activation of G protein-coupled receptors. Through the localization of these GTPase-activating proteins/GAPs, it also probably plays a role in G protein-coupled receptors signaling in neurons. Also probably plays a role in cell adhesion by palmitoylating CD9 and CD151 to regulate their expression and function. Palmitoylates the endoplasmic reticulum protein CKAP4 and regulates its localization to the plasma membrane. Could also palmitoylate LCK and regulate its localization to the plasma membrane (By similarity).
Subcellular location: Postsynaptic density {ECO:0000269|PubMed:19596852}. Postsynaptic recycling endosome membrane {ECO:0000250|UniProtKB:P59267}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q9UIJ5}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9UIJ5}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9UIJ5}; Multi-pass membrane protein {ECO:0000255}. Note=Translocates to postsynaptic density when synaptic activity decreases. {ECO:0000269|PubMed:19596852}.
Interaction partners:
Sequence:
MAPSGPGGVRRRCRRVLYWIPVVFISLLLGWSYYAYAIQLCIVSMENIGEQVVCLMAYHLLFAMFVWSYWKTIFTLPMNPSKEFHLSYAEKELLEREPRGEAHQEVLRRAAKDLPIYTRTMSGAIRYCDRCRLIKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQYFIRFWTNGLPDTQAKFHIMFLFFAAAMFSVSLSSLFGYHCWLVSKNKSTLEAFRNPVFRHGTDKNGFSLGFSKNMRQVFGDEKKYWLLPIFSSQGDGCSFPTCLVNQDPEQPSTPAGLNSTAKNPENHQFPAKPLRESQSHLLTDSQTWTENSSNSGRCKAGMSNPALTMENET
Protein: RE66405p (Q8IGM1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNLEDISMIMKLFDSNMHKLQGNLRSYQTEMHQIHKELTEKLSHADLLYRSLIPLHDHLVASLSEVNAHVMKLNVQLHINRQSVRLGDYEYYEKSIDNPYSSIRSGLQAIEKPGCAEAICQSSKPAFVECLPSSTSEEVPVVAVQEASSTNQLDAISVVNENLSEERDATPQPLAVSKNMEETMPSNPFHEQLEGSLEEIPVGSKIVVETEKANNPVRSEASAPATSDNQSLLAAKQGTQTIGTGICNKISKSTINMPNNWQLENPTEVTAASIEKVNKLPKSPRNRFLLPPKGGTETTRRDIYNQILKDMAAFPENTIVTAVLASVDVTDNCAYVAKWDESSDRIKKVLQRQLPLQELDQLPDYGDIFAVLDSINNIITRITINSSSAGGGYDAYLIDFGEHIHFDGNETIFKLPDDIKRLPAQAIRCDLINCDIANMHCFVNTYIKIRVHENNNSTLVAEPVIDRLSRPTKTNTTKYPAGITEDDMAMLNEIDESTSDPLKAVLGFRPKDEQRICRHYDPKLNGCFKGNNCRFAHEPFAPNGATKDVELARALPETIFDTTVHFEIGSIVGILITFINGPTEVYGQFLDGSPPLVWDKKDVPENKRTFKSKPRLLDIVLALYSDGCFYRAQIIDEFPSEYMIFYVDYGNTEFVP
Protein: Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11) (P68930)
Organism: Bacillus phage phi29 (Bacteriophage phi-29)
Function: Forms the proximal part of the tail tube.
Subcellular location: Virion {ECO:0000269|PubMed:11562162, ECO:0000269|PubMed:8985375}. Note=Present in 12 copies in the virion (Probable). {ECO:0000269|PubMed:11562162, ECO:0000269|PubMed:8985375}.
Interaction partners:
Sequence:
MSSYTMQLRTYIEMWSQGETGLSTAEKIEKGRPKLFDFNYPIFDESYRTIFETHFIRNFYMREIGFETEGLFKFHLETWLMINMPYFNKLFESELIKYDPLENTRVGVKSNTKNDTDRNDNRDVKQDLTSNGTSSTDAKQNDTSKTTGNEKSSGSGSITDDNFKRDLNADTADDRLQLTTKDGEGVLEYASQIEEHNENKKRDTKTSNTTDTTSNTTGTSTLDSDSKTSNKANTTSNDKLNSQINSVEDYIEDRVGKIGTQSYARLVMDYREALLRIEQRIFNEMQELFMLVY
Protein: Uncharacterized protein (Q584W0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTSSRAAGRLRSATKRTEKIKEQVMKSSTSVSRRTIPPSQRKMLEQTQSVSQLSEASTGNLPPHKLSQRELVRVHGWEPVVKPLRDTDAVSLPGTATTGVVWRNDITNATLIPNDVGGGVRTRRAAARLAAGVEPPNYLVYSRDPHVKSKRRGQHNVHVTEDVPSASASGAVLSGVSLTLSKAVRSRWRGIKSVDNGENKQQDGNEIGEDKPNSVGDDDAKFVGEGNGEKRQDGRVKKSEGPEEIEEENGADSIDAKEEKVGKVEDMGEMKENVEEQNNNPHSDEEITDQSEDEKESGEEVGNETPAEDAENREGDGDTPRGRRRRGLASWLSRRRSRFGCERRKRRRAEAVTSADGQQQQQQQQRIGTLSASQAMLPPPYRRNRRLKRKLDVTEDSPIFASHAELRDKASHIFARAPFSTDEDVLRSTIDWRDNPTLLYARLLWELAPREFLGIVTKRQEERTASSVLQGANSTISVKKE
Protein: G5-interacting protein (Q381X8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSLNPNAPPWNVPDHNMDHGMDPHGRHGHQDPRFHNFSGYYPQHMPMHQMQSVQNMGMPRSMMNHGYNHPAAHIHPMQHSAPPGQAFHQGRARGQAYLGGHVNAMPAVPAPSYRKQHIVVVVVLGYRCVGKTTVARQIAKVRNYRYVSLKPSEDAGSVSPEAFVAPVVELLASKNSYEGIVIDDIVSQNKYDPYYVQSVLQKHGLKLDVVVLLDSELDNAKEGVDYEDPQQRKLHPESYEFCACHLNGGNAVVVECRGKDLDETVAEAMRQLNDVNIVKESTITLKEVALMPNCPLVCNPSMVTEVLAAQSGVLGLAESASFPFSEPNYLLEYTIFARQAHAFRSYMIIPWIKGDKVSLIGYKDAIYLHLPAYNILFQLNDSPTALTHLLKETTATGGLAFIFEATFAANKLHVSDLLLLGGMKGSEMLVNERVDLLKEKLGELREGAVQLLPWYPVKDMEMCKKENPEADGILFVNPDGIQVGEYDSRNYLYPLHRKKTVELRIWNGNFTGGVWTFDAYCEEVGTEKLVEGIPVHINDDVVTEYCINDGNILECTREEQSVGTNKARKGGKHYVFKSRCQWASKPTTTYKQECFVNEPKWPSDRLAQACAAITYTPAVRREVQNEASG
Protein: Reticulon-like protein B8 (AtRTNLB8) (Q9SS37)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9SH59}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Histidine-tRNA ligase
- RNA exonuclease 4
- Mannose-P-dolichol utilization defect 1 protein homolog 2
- Reticulon-like protein B18
- Uncharacterized protein At2g34460
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
- Transcription regulator
- Style cell-cycle inhibitor 1
- Large ribosomal subunit protein uL30z
- Clathrin light chain 3
Sequence:
MPDKNIVEDVIGDLVDNFTETVQKNKHGSSFFEQEDSVSSRFNRLFDRQKPIHHVLGGGKSADVLLWRNKKISASVLMGATAIWVLFEWINFHFLSLVCYALLLGMIAQFVWSNASGFLNRSQSRVPRLVLPKDFFAEVGVAVGKEVNRGLLFLQDLACKGNLKQFLMAVIGLWVAAMVGSCCNFLTVLYIGFVGAHTMPVLYERYEDEVDGFMDSMIMKFHSHYKKLDTGFLSRIPSGKFGLKKRE
Protein: Uncharacterized protein YER053C-A (Q3E7B0)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable aminopeptidase YDR415C
- Uncharacterized vacuolar protein YLR297W
- Putative uncharacterized protein YGR182C
- Uncharacterized protein YOR343C
Sequence:
MQDLEIFLSIFAFIFVFYFGAHRTVMNRNKSDVPYLQ
Protein: Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (Q6PDL0)
Organism: Mus musculus (Mouse)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O43237}.
Interaction partners:
- Cytoplasmic dynein 1 heavy chain 1
- Cytoplasmic dynein 1 intermediate chain 2
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic dynein 1 light intermediate chain 1
- Dynein light chain roadblock-type 1
- Dynein light chain 1, cytoplasmic
- Dynein light chain 2, cytoplasmic
- Dynactin subunit 1
- Dynactin subunit 6
- Cytoplasmic dynein 2 heavy chain 1
Sequence:
MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLKFAVSAESLRETLVIFVADMSRPWTIMESLQKWASVLREHIDKMKIPPEEMRDLERKFMKEFQDYIEPEEGCQGSPQRRGPLTSGSDEDSVALPLGDNVLTHNLGIPVLVVCTKCDAMSVLEKEHDYRDEHLDFIQAHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTIPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRTSESPARGPSGSPRTQGRGGPASVPSASPGTSVKKPDPNIKNNAASEGVLASFFNSLLSKKTGSPGSPSAGGVQSTAKKSGQKTVLSNVQEELDRMTRKPDSMVTNSSTENEA
Protein: Putative glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (Q9HTE2)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Glucose-6-phosphate isomerase
- Phosphomannomutase/phosphoglucomutase
- Glucokinase
- CsaA protein
- Low specificity L-threonine aldolase
- Glucose-6-phosphate 1-dehydrogenase
- Glucose-6-phosphate 1-dehydrogenase
- Transaldolase
- 2-dehydro-3-deoxy-phosphogluconate aldolase
- Ribokinase
Sequence:
MILLPSIRLPETAMNTDSPINRVEQVQVDDLACWRIHTAHGEALIAQQGAQLLSYQPHEQPPLVWLSDEAGYRRGQSVRGGVPVCWPWFGPLERNPQEVRGQVEDGLKAPAHGLVRAVDWKIDDIAEEDGDLCVSFRLDAPDGLPGWPHPAALRMLFRFGERLTLRLTSENLGSKPLVLSQALHTYFAVSDSREIAIEGLEGARYIETLENWEERTQHGAVRVKGELDRIYLGLERDLLIKDPRWERSIHLHALDSRSAVVWNPWVDKSRRLSQFADDAWQQMLCIETGRVWDDLMVVAPGRSESFGVQIWSEPLKRP
Protein: DOP1 leucine zipper like protein A (A0A8I6A0N6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395}.
Interaction partners:
Sequence:
MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPTLLSLYEIYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDRAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRRTLHARLEVGPGDSSDASEFQLTTFCSLVDFLLDIVSLPTRSMRVLCQETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGTGGVVQFPSGQNSAVKEWEDKKVSSVSMENPTEVFEDGENPPSSRSSESGFTEFIQYQAERTDDLDRELNGQGTATIPIGSTSSETETASTVGSEETVIQPPSTLTQGAAGRTGKAVQKTAMQCCLEYVQQFLSRLIHLYILHSDSFPQASAADHQSDLSRIQRDTSKWDRDSQGDAKERNIHTPKTSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGENINSMEPAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPSSSICEDVVSQQLTHKDKKVRMEAHARFAVLWHLTRDLHVNKSSFARSFDRSLFIMLDSLTSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGSREKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENVSAHEDSHLAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDFDLGKEATKTEDQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLTDSSVSSETKSRQRSHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQTNVFFSDGLDLENWYSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKSNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKTAGKNMVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVMTIPEESEAGFDFVVSDLEHVSPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEKMGLAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNGRRQNKTPSRTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSLEVCMLQFFYAYIQRIPVPNLVDSWASLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVSHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAKKNPEEDGSARTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPILYSNSFPSKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT
Protein: Exophilin-5 (Synaptotagmin-like protein homolog lacking C2 domains b) (SlaC2-b) (Slp homolog lacking C2 domains b) (Q0VAV2)
Organism: Mus musculus (Mouse)
Function: May act as Rab effector protein and play a role in vesicle trafficking.
Interaction partners:
- Ras-related protein Rab-27A
- Ras-related protein Rab-27B
Sequence:
MTKVPQGFDFSFLNEEEARKILQVLERNEELRRAEKDRISKLQKTKRDIRWLQGATGEWFEEIQRKKFCNETDVNQMLKPPLTYRLQKGMAKNDPMELQTPRSKSLINQKPSVSSRMSFRSSFASLFSFRRPAKETLKLQSPRPNRCDERVRPSASVRGTASAKIYNSPVGNQPVASVFVPKPAIMREESGMPPPWDASLLESEFFQVLDDLDNKLAQEQSSGLMNTRVPFNYGSRTQFKLSHRNSHGHSTGRQQNYHSETSNMSIYNILRPGTPREGFKTFSPRTKTIYDMYRTREPRVLKEDFMQKNAFGSASLCFDSRQRSASPATGSFTARSLHFPADTQNKSSFTPVRHQQSPKRTPLSSIIWNRSDASRHRQNQEESLGVQAPMDIDPEEQYVSPRCFQESRRYEMCHSQNAYQSYPLNVPVANAMSPDTLENSENMPFYRQSNPFARSFFSSTFRQSREQRFGQNSFWSRQEEYSSWSDFPQSRGPFPSSDKDFEMFSVEANRAPSVCSQGVPSQHWRSHSSGHGTYVFRGREDSHCWRSDFQTSPLESMDTSHVNENQHPPHFVTPVGFSITDSSCHLQSSRLDSQQGYFPVEEAVDEDPYLCGKAQTPASSFRTPFPLSPDDGRESQSSSFPDSTATLQKIIPNKPDFLPIRNCTEVPVACSHSTDSLSLTDTQPNIPVTETNSEKDMDVSVSKDEQLNKTGQKSRPTGLPQYVLHTVISNDLPDFQNAHSRDSAQNDRYGFNAPATERSRRSPRVFSRKGTSQIHTTQRDQSNKLSKNKCFGGDRTLDSAASPPFIQESGTATSLPSPNQGCHQKTGSNEESSNTIKNSHWCFESTANQKSQPSREPALLDLEQSLSTHSTNDSKLAPGHSISRAPLHVASDAPQESFLDARLVPSTTVFSRSLSDQDPGQEQREEKDKATKSQDNQLAVNSTDNQESHDSPALPHDAVHCHPYSPFKNGRGKGRVRRRVSCIEKLTKTERAAAPTREGSGCAEDQRSIKDPELSTVYCTLPRKPASFLIHSRQQESKGTVASVRNGPLPFQIKNKAEVPTGKSTSDKPSSPESVSDAANAVSGTPKATKKMTDMKAIRSASVRKGPLPFLIKRAISCPSGEPCSLAESDDRQKSSVLGMDASPVIPRPGGRIFNSLEGEPSFRESAFSEKELAQEHTGKDRELRAPRMGLFNPSKKTPERLCATGSGKESGRALHKFKTTSMFSVSGDEENVNCLEVVSIYYTLPRKPSKKFCSLLQQYTQGTDSLRDAFQGETEALPNALEIDELNCPAQVQSGIPPPQDPKMQVDSAPCCLSHSPESKDVSQLPDRETSKSTLEEMTSVGPDVSLHREEPTTKEISPSNVSKTAIDDSLSREKREKELLRQILRAPLLHQEKGAGKEHTKSHQQPSKGGNSGPSGLPSRSEDNDENSQTRRDSGTCAGGMASGNGQYPWRDHMAAVVGDRSSRSQPRETSGTTGSDCQNPTDKMLSDSESQAFALTPALCKLQLAEEAQPGGAGLQSEASQAGSQETNTAEMRKVEDEEHMLTRDQTLLPRGNNKNKTNTDETKDRYSGKHRLAAISKASKRIPAKDLSPRKHVATIFSQSESESGFRRLSLYRPEDNPLSPEPTVKATESTDESSQMNVDKSETLLQETTVSSPGPPGQPCHQKSASILQPHLNGSPGVLETPPKSEGSKTQISGELGAPAQLTLTSPLEKGAGHQQRLSPPFPLEPTQKSTINSHCQLRHRSAPSPESEPEPHLYRSKSLKNFNVQSDLLCASHPPKARGRHFSENTSIDNALSQLSLEDGSFPNSGYNRRFKSSSELPASYESESWTSYSNRTRGPKSTSSISRPIDYGIFGKEQQLAFLENVKRSLTQGRLWKPSFLKNPGFLKDDVLNASNLSQSELVNSPAGQAPEDGVFPSEPLNIYKDDPVEPLVSDWDTDTTTDDEYYLDEKDKESEL
Protein: Nucleoside kinase (NK) (ATP-dependent nucleoside monophosphokinase) (Cytidine kinase) (EC 2.7.1.213) (Guanosine-inosine kinase) (EC 2.7.1.73) (Q57849)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: Catalyzes the phosphorylation of a wide range of nucleosides to yield nucleoside monophosphates. Shows the highest activity for inosine, guanosine and cytidine, but very poor kinase activity with adenosine, thymidine, uridine and xanthosine. ATP is the best phosphate donor, but can also use ITP and GTP. Shows extremely low activity with fructose-6-phosphate.
Interaction partners:
- 1-
- Adenylosuccinate synthetase
- Hypoxanthine/guanine phosphoribosyltransferase
- GMP synthase subunit B
- Inosine-5'-monophosphate dehydrogenase
- Cytidylate kinase
- GMP synthase subunit A
- 5'-nucleotidase SurE
- IMP cyclohydrolase
- Bifunctional ADP-specific glucokinase/phosphofructokinase
Sequence:
MGGKMEKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLSCVGYDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKELNPPNFNTEIVHIATGDPEFNLKCAKKAYGNNLVSFDPGQDLPQYSKEMLLEIIEHTNFLFMNKHEFERASNLLNFEIDDYLERVDALIVTKGSKGSVIYTKDKKIEIPCIKAGKVIDPTGAGDSYRAGFLSAYVKGYDLEKCGLIGAATASFVVEAKGCQTNLPTWDKVVERLEKHRI
Protein: Peptide ToHyp2 (C0HKQ4)
Organism: Taraxacum officinale (Common dandelion) (Leontodon taraxacum)
Function: Antimicrobial peptide. Inhibits elongation of hyphae in B.sorokiniana (IC(50)=3.8 uM) but has no effect on this process or on germination of conidia in a panel of other phytopathogenic fungi. At concentrations above 10 uM, has antibacterial activity.
Interaction partners:
Sequence:
LPKPPLLPPPVPGLAPGLPPLPVPDPVPHPPKKPP