wanglab/gogpt-training-data huggingface dataset:
Protein: Reticulocyte binding protein 2, putative (A5K736)
Organism: Plasmodium vivax (strain Salvador I)
Interaction partners:
- Reticulocyte-binding protein 1
- Reticulocyte binding protein 2
- non-specific serine/threonine protein kinase
- Nucleosomal binding protein 1, putative
- Serine/threonine-protein phosphatase
Sequence:
MHIPIQPSPESTQITNTTDNIDYFDISDESNYYLISQLRPHFSNIYFFDEFKRYASYHTEIKRYEDIHKTKVNSLLNEASRAIGICNRAKNTVKGLINILENPQKFKTQRESYDVKLRQYEEKKEAFRGCLLNKNRKNLDQIKKINNEIRDLLEKLKCSQDCQTNVYFDMIKIYLVDFKKMPYENYDTFIKQYKNSYLSGVDMIRKIEKQIDNPVTINAIKFTQKEMGYIIDRFEYHLQKVKHSIDQVTALSDGVKPKQVTKNRLKEYYFNIGNYYSIFKFGKDSLNMLNKALIHKEKIVHNLLGELFGHLEERISKLIDSEYFITESNNIISQSEETLKLAEDVYDKNTKLIEDLTLYPHLEINEFKKDYDNNVEDLRESIIYIQSYVSSIKSAYRYNVLEKDSVESKQKNIPANSNAQKKVDELLSIIDSISYSNFSVAENFQKMKDYYKEIEKLKIKILQLIEAIKKYQQHVEELINKEKAVAILKEDINKIIEYIKGIIEKLKQLISANKDFDKIFQQVEQLINEALFNKDQFEHNKNDLHTKMKEIMHTFHERDLQQFLDNMSKFLKDQEASYQNADSKEKLDQLLTTVKAKQDELKEMKCDDIPDIIDNLKKESQNVLNLKDEVINKQFENMRTEMSSSLDQMTKEYNALKSSIEEYEAEKKGIENHKQNIIKRKNTFIVAEHENDEDVPEGKNTYNEFISNKDTILQKESAISNQMNTLEEKKRNRKTTLQTYGDAIQKLETYTEKKDEETKVLLDKFNTEVENFKLDEDEKSFNDAKSIVSNTINEVENENKNIDSIKKVNIAMKRSRSNQQSVEQLIRNKDNLLKEKMEKHFQKINTDEIIGQSAKANLLNNLESEKAIINEQLNDAHLNDLKLQIEKTLSYCEKSRENIKGNNGTHPEELNASEIEWEATKGKIETLNSNYQALNKNMDDIINKQHDEMIVLIDRDIKEKGKDIELKVEQRIQALEKMKAKLSSFDTNEDVKKYQSDINKEELIKLKEMSTAVLNKIDQNKNQLINVKTKSSGYVAESNGIKNKQTEPSQEKDKQIVYNTNRGDIEKVYKNIRDMYNELDDVEKEETTSNEVDNIEMQYDRLLINLLVQKINEENTKAKGLMEEIKSYIENIESVQAKMSDETREGATEFEFNQYQQSSLANDKKITEIVQHAINKKGEAERSKKTNEVKSIKNDVNTYMQQVIDEYNAMQKALGDIKNVNDLLISTSGRRIAEEISKSTNEAENFEKQAKGELGKINDIIEKMENQMVQAKEHENKIHINLEDKQIDEEVQKIRQIHEELINTKIAMNEHLSKTKAAKENCLSQVRNAERGKIKIDFLNNNKQSSNLKDVNMDHVTKNIADCVEHSKEVNKTENEAEKEHDLFLEYEKDITSILNRSSILGIETKSKKRKNEATKIMGQIEGEHSIIKTELQQSSENFKQLNEKYNLSEEKSMLANPTSTKANESIQYNIGKVKQNLLYIDNIAKEVDTILTNAQDSIRSISQISKLDGRNTLQMVEKEAADYVKYLDKITKEKELMNDKHKDLNPIKSDIANIETELKKHRKLFEIGLLNKVIEIAKTRKLYMDSVEQLLNSSINNFVTLFNGFNLKKYKIETSLDVYKGKISEFHTEFLQPYESIQNKEKRVLDPSVDFSAAKNMREEAQKEEKNIENVEKKTKKYLSDINKMESFTFIRNMRQTLDELSKTCKQEYAEVEGGHKDIEKIIEDIKSLNDESGSSAKLQQAEDKNSQMKAKVNHYSLKKEAHTILEQIVKSANFVGITIVTALQPSDLAAKASLQKAPELQFESQSKVTLESGQFLEKKNQLDVHENVQAAYNTVLQIYKYSDDIVRKQEKCEQLVKDGKDICLKFKSINEIKVMIQNSKGKESTLSAKVSHSFNKLSELNKIKCNDESYDAILETPSREELNKLRSTFKQEKDTIANQAKLSGYKTDFETHIGKLNDLAKIVDNLKASETLPKNIEEKKTSINLISTKLETIEKEIESINSSFDQLLEKGKKCEMTKYKLVRDSLSTKINDHSAIIKDNQKKATEYLTYIQNNHISIFKDIDMLNENLGEKSVSRYAIAKIEEANDLSAQLTAAVSEYEAIANSIRKEFTNISDHTEMDTLENEAKMLKEHYDNLINKKNIITELHNKINLIKLLEIRATSDKYVDIAELLGEVVKDQKKKLQEAKNKLDTLKDHIAVKEKELINHDSSFTLVSIKAFDEIYDDIKYNVGQLHTLEVTNFDELKKGKTYEENVTHLLNRRETLQNDLHNYEEKDKLKNTNIEMSNEENNQIRQTSEVIKKLESEFQNLLKIIQQSNTLCSNDNIKQFISDILKKVETIRERFVKNFPEREKYHQIEINYNEIKGIVKEVDTNPEISIFTEKINTYIRQKIRSAHHLEDAQKIKDIIEDVTSNYRKIKSKLSQVNNALDRIKIKKSEMDTLFESLSKENANNYNSAKYFLVDSDKIIKHLEDQVSKMSSLISYAEREIKELEEKVYSILNRPVIDNSASEQIKLLSDTQENDTDEAQKREFAEEQILNLPKQQIHSDEGNNNDMSTTDSANEEKQTGEEESQHEDQSQPRGIHSRVRLAEGIILGLSVFSGIIFISFRHKDEEKKDPESVGEQFEGNNNFNEDDKEEVIDVCFDNSDYSE
Protein: GPI transamidase component GAB1 homolog (O13883)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- GPI-anchor transamidase
- GPI transamidase component gaa1
- GPI transamidase component PIG-T homolog
- GPI transamidase component PIG-S homolog
- GPI ethanolamine phosphate transferase 3
- GPI inositol-deacylase
Sequence:
MIPNEKLKLLGLLSISFFLQWYLANTWIAEFLYRRIEVSTPVSGFLRVREGLYLYENGLDPYSGGVFYQSPLLLILNYCCELLGGISVTRFVYTSISTMGGLFVYLIAKQARVLDPNQVLSTCSPLWISVIYLLNPLTFLPGIACSADMILNFTTLMTIYFASCGSYAIYACCMALTVFINPNALLLFFPSYLILRKCNSSIKFRQIFVVFLFYLAGLIITSGFFLNSLSFLKIPFRVYLDSHDLTPNLGLWWYFFTEMFNEFRTFFLFVFAILPLMFVLPVSIRLYYLPLPITIALIGLHSLFKAYPSICDLSIFLSLLPIFNKVQDRMRYSLLTNNAIVFALVLGSAFYHSWITLGCGNANFYYASNLILALGLSLKIMDFLKALLLVDWYANHPQHENIPLKQVQ
Protein: Membrane-spanning 4-domains subfamily A member 6E (Q96DS6)
Organism: Homo sapiens (Human)
Function: May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Membrane-spanning 4-domains subfamily A member 4A
- Putative membrane-spanning 4-domains subfamily A member 4E
- Membrane-spanning 4-domains subfamily A member 12
- Membrane-spanning 4-domains subfamily A member 10
- Membrane-spanning 4-domains subfamily A member 8
- Phospholipid-transporting ATPase ABCA7
- CD2-associated protein
Sequence:
MTSQPISNETIIMLPSNVINFSQAEKPEPTNQGQDSLKKRLQAKVKVIGVHSSLAGSILSALSALVGFILLSVNPAALNPASLQCKLDEKDIPTRLLLSYDYHSPYTMDCHRAKASLAGTLSLMLVSTVLEFCLAVLTAVLQWKQTV
Protein: UDP-glucose/GDP-mannose dehydrogenase family protein (Q725J7)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- NAD-dependent epimerase/dehydratase family protein
- Bifunctional protein GlmU
- UDP-N-acetylglucosamine 1-carboxyvinyltransferase
- Glycosyl transferase, group 1 family protein
- Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
- NAD-dependent epimerase/dehydratase family protein
Sequence:
MNEQTSFDDIASGRTAVAVVGLGYVGLPLAVALARHFRVIGFDIQQNRVDELSSGHDRTGEVDDASLAATPALFTTDAARLGEAGVIIVAVPTPIDNHRNPDLGPVEKSSITVGRHMKAGCVVVYESTVYPGVTEEVCVPILERESGLVFGRDFTVGYSPERINPGDKVHTLETIMKIVSGSDAATADLLEKVYGSVVTAGIHKAASIKVAEAAKVIENTQRDLNIALMNELSIIFDRLGIDTLEVLEAAGTKWNFLPFRPGLVGGHCIGVDPYYLTFKAEELGYHPQVILAGRRINDGMGKHVAEMTVKRMIRSGCRVAGARVGVLGLTFKENVPDLRNTRVIDVVRELEEYGVTVLVHDPFADPAEAMHEYGLTLAHLKDFQQLDALVVTVPHDVYRAMDLVQVRRWCASSGTPPLLDVRGTFNPGTAREAGFDYWRL
Protein: Chloride intracellular channel protein 5 (Glutaredoxin-like oxidoreductase CLIC5) (EC 1.8.-.-) (Q9EPT8)
Organism: Rattus norvegicus (Rat)
Function: Required for normal hearing. It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti. Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture. Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens.
Subcellular location: Golgi apparatus {ECO:0000250|UniProtKB:Q9NZA1}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9NZA1}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9NZA1}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9NZA1}. Membrane {ECO:0000250|UniProtKB:Q9NZA1}; Single-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:17021174, ECO:0000269|PubMed:24285636}; Single-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:O00299}. Mitochondrion {ECO:0000269|PubMed:26777142}. Cell projection, stereocilium {ECO:0000269|PubMed:24285636}. Note=Colocalizes with AKAP9 at the Golgi apparatus as well as, to a lesser extent, the centrosome (By similarity). Associates with the cortical actin cytoskeleton (By similarity). Localizes to the apical region of cochlear hair cells, at the base of the actin-rich hair bundle (PubMed:17021174). Colocalizes with podocalyxin at the apical cell membrane in renal glomeruli (By similarity). May localize to the centrosome in lens epithelial cells (By similarity). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity). {ECO:0000250|UniProtKB:O00299, ECO:0000250|UniProtKB:Q8BXK9, ECO:0000250|UniProtKB:Q9NZA1, ECO:0000269|PubMed:17021174, ECO:0000269|PubMed:26777142}.
Interaction partners:
- Taperin
- Radixin
- Phosphatidylinositol phosphatase PTPRQ
Sequence:
MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAARHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALRKLDDYLNTPLPEEIDTNTHGDEKGSQRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVARRLSRS
Protein: Stac-like, isoform R (A0A0B4KF73)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGISAHAAPASFWNHPRRIRRTPTSDRDGVDQCRPWICRRKDRRPAHPAANRPPESRVCGPSSTFRWDDWAAPAPRTRERATDCARMCMCTSRIPYSVARICARTTSMHSSRPASRSSSFIRRPLTRRQRMAVGGVTRRLWRTMRVYTIHQGRGVRRARAAQAVAAYLRDRRARIGKGWPAQGHGVRISATEQWADKPVVRRPGDPTRRVAAGAVPVLAERLPKVTGSSVKSSSGRRSRRRRIFGWRGPRGGSLSPQGGSMASYNGVLKDYSHSSLNEAFKSQNNVNFKLIKTVSDFSETLSRLYEEHATALQVAVSNYRKKNAELRKERPACHLAIFQAWETFLQEVETDSQACNDVASVLSRQVSRPMLDKSFHRKVQSRKIFTHRESFETIIAKTEEKLSKCRVDYKQCHLAHRQNPSQHSLTEYIDAHNAYVQQLHATNGMLEAYHTDTLPQQMQELEEIHNDLVAIVSDSLMQGAEVIAGKANDQAKRYNSLSNQCAAVSPQQDLVNFVRLLAQPSQAQKIPRRLFASPQAEVGEEAGDHNEMTPCLRNELVFDRHSTLSQRSALESLKREAIELELQIRQLQDSIEALNRTQTRGIEGQLYNKVNELQEDLSMKKFDLRAKQIHLAAIRAQKDLFVSKVEPTSPRNERKFSAATAPSMKTKWLKAFKSLKPAGSGSAQQADRRNGASSTASEPLRPNLDGSHHLQEYTYKKITACDVCSQILRGHTRQGLRCRICKLNAHGDCAPNLPRCQPKQKLLRRQKSTSELENRVDIEEETGADKSVQAKQMDGSVAGGSALPVPVLSERELGRAPPPDIPIVSVSELALQEQQQQQQQQQQQHQQQQRSLASVAQAAAVRAGRGVRPPPVAMPILGVQLQQQELQQQRGGLPVPSQDISSSSEPRYGQFFAPVSNMSSSAYISNGIGINYYTGNTQQVAYMQQVPATSSSISAGTSPAHQQQQQQQPQQCGGSTSGSSINYSTTDPGLRRRLFAGIRPLSVFGRLRQQRSSQHRSISLPETSANPKSETTRPFGEPLMLLKSTESNPDESKGNRRVR
Protein: Ubiquitin-like domain-containing protein (Q38C18)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSREPTAANVEATEVCVVVSHAARKFQITLPAATATVGDIKNRIEQSTGVPVERQRLLFGAHTLKQYRNGDIENVRLIDIVVKPSGRANEKGIKAPAGTNDNPKEGRDDNSSSGNGTVTLTSGSVITLPVMLLGTAASAPHVDEEVTAQLHRLVTTTLEHDSRWFRCSYGKGYARQTAFVCRTCVDSGAADPSHAICYACAEVCHTGHDVEEWGVRYFMRCDCCTPVCWRDIKVNGSKEEWDKKAVNDHSSEGNRGQGDENSKMSRGVLPLIRKAEETRQLKRCCFILDSETSEPPVSREAVPLNGRNIYPRSSYAWCFCCCEDDYPPDGTNESAGVVCMLCATCFWSAHITRLHTGMLNRLPCHGNLVEGDVVAFYCETCKGVVCGPCRLRCHADHEVQKDVVVAPYEQHGKGAVANSRDHTFKCECGCFSSDKSAGDDGLNDRNASLLPPNTAVDIMNSDSLIGFICAYCMQEHPWLADRDYRYCYGGKLPDPVPKEQHKPIVSCNFPPDAECPDDRYPFHGMLFSVDAFTEKMTCKCAPCRQAYERFAPRTTTTAQDEMAVELHEACDHCGRNIRDENAFMCQTCELCCGKAFFVCRRCNSLRLGLNLPTPSSTNDESVHGNTQEGNTVSSTEQEDEPASWDHPSDHVFLEDTCENLFNLCGMCVAHHLGPQAEDLSSMDAESIAGTVMTVLQRTFGEAPLTFDPKDIAQHHQLLQQQKKKPNASANTQSSSNERTGRRVSPASIAKGCKRPRIEESEDDSDVRNGVSSGSGAHDGDDQI
Protein: Adhesion G protein-coupled receptor E1 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor) (Q14246)
Organism: Homo sapiens (Human)
Function: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24530099}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Secretin
Sequence:
MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQPKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASKTG
Protein: Syntaxin-6 (O43752)
Organism: Homo sapiens (Human)
Function: SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:23818989}; Single-pass type IV membrane protein {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein {ECO:0000255}.
Interaction partners:
- Vesicle-associated membrane protein 4
- Syntaxin-12
- Vesicle-associated membrane protein 8
- Synaptosomal-associated protein 29
- Vesicle transport through interaction with t-SNAREs homolog 1A
- Vesicle-associated membrane protein 3
- Vesicle transport through interaction with t-SNAREs homolog 1B
- Syntaxin-16
- Synaptosomal-associated protein 23
- Syntaxin-4
Sequence:
MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLVL
Protein: Leucine-rich repeat-containing protein 47 (Q8N1G4)
Organism: Homo sapiens (Human)
Interaction partners:
- Phenylalanine--tRNA ligase alpha subunit
- Serine/threonine-protein kinase RIO1
- Phenylalanine--tRNA ligase, mitochondrial
- Ferredoxin-fold anticodon-binding domain-containing protein 1
- Small ribosomal subunit protein uS15
- Probable RNA-binding protein EIF1AD
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS17
- Tyrosine--tRNA ligase, cytoplasmic
Sequence:
MAAAAVSESWPELELAERERRRELLLTGPGLEERVRAAGGQLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKRLEKMVSGCQTRSILEYLRVGGRGGGKGKGRAEGSEKEESRRKRRERKQRREGGDGEEQDVGDAGRLLLRVLHVSENPVPLTVRVSPEVRDVRPYIVGAVVRGMDLQPGNALKRFLTSQTKLHEDLCEKRTAATLATHELRAVKGPLLYCARPPQDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGNENYPCLVDADGDVISFPPITNSEKTKVKKTTSDLFLEVTSATSLQICKDVMDALILKMAEMKKYTLENKEEGSLSDTEADAVSGQLPDPTTNPSAGKDGPSLLVVEQVRVVDLEGSLKVVYPSKADLATAPPHVTVVR
Protein: Catalase isozyme 1 (EC 1.11.1.6) (P17598)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Subcellular location: Peroxisome.
Interaction partners:
- Enoyl-CoA hydratase 2, peroxisomal-like
- (R)-specific enoyl-CoA hydratase-like
- (R)-specific enoyl-CoA hydratase-like
- Peroxiredoxin
- Peroxiredoxin
- L-arabinolactonase-like
- thioredoxin-dependent peroxiredoxin
- thioredoxin-dependent peroxiredoxin
- 2-Cys peroxiredoxin BAS1-like
- Non-specific lipid-transfer protein-like 1
Sequence:
MDPYKHRPSSAFNSPFWTTNSGAPVWNNNSSLTVGPRGQYLLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFIRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFTFLFDDLGVPQDYRHMEGSGVNTYTLINKAGKAHYVKFHWKPTCGVKCLLEDEAIKVGGANHSHATQDLYDSIAAGNYPEWKLFIQTIDPDHEDKFDFDPLDVTKTWPEDILPLQPVGRLVLNKNIDNFFAENEQLAFCPAIVVPGIYYSDDKLLQTRIFSYSDTQRHRLGPNYLQLPANAPKCAHHNNHHEGFMNFMHRDEEINYFPSRYDPVRHAEMFPIPPAVCTGRREKCIIEKENNFKQPGERYRSWAADRQERFICRWVDALSDPRVTHEIRSIWISYWSQADKSVGQKLASLLNVRPSI
Protein: Anaerobic C4-dicarboxylate transporter DcuB (P0ABN9)
Organism: Escherichia coli (strain K12)
Function: Bifunctional protein with a transport and a regulatory function. Responsible for the transport of C4-dicarboxylates during anaerobic growth. Catalyzes the uptake of fumarate, malate, aspartate or D-tartrate coupled to the export of succinate. Can also catalyze the uptake (without exchange) of fumarate. May function primarily as a C4-dicarboxylate transporter during fumarate respiration. Required for anaerobic growth on D-tartrate.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:21634397}; Multi-pass membrane protein {ECO:0000269|PubMed:21634397}.
Interaction partners:
- Fumarate hydratase class I, anaerobic
- Sensor histidine kinase DcuS
- Anaerobic C4-dicarboxylate transporter DcuC
- Aerobic C4-dicarboxylate transport protein
- Putative cryptic C4-dicarboxylate transporter DcuD
- Transcriptional regulatory protein DcuR
- Aspartate ammonia-lyase
- Sensor histidine kinase DpiB
- Fumarate reductase flavoprotein subunit
Sequence:
MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLGNVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREYVYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL
Protein: DNA-directed RNA polymerase I subunit RPA43 (DNA-directed RNA polymerase I subunit F) (Twist neighbor protein) (Q3B726)
Organism: Homo sapiens (Human)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters.
Subcellular location: Nucleus, nucleolus {ECO:0000305|PubMed:34887565}.
Interaction partners:
- RNA polymerase I-specific transcription initiation factor RRN3
- DNA-directed RNA polymerase I subunit RPA2
- DNA-directed RNA polymerases I and III subunit RPAC2
- DNA-directed RNA polymerase I subunit RPA12
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase I subunit RPA49
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
Sequence:
MAAGCSEAPRPAAASDGSLVGQAGVLPCLELPTYAAACALVNSRYSCLVAGPHQRHIALSPRYLNRKRTGIREQLDAELLRYSESLLGVPIAYDNIKVVGELGDIYDDQGHIHLNIEADFVIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNASIPKPEQLSAEQWQTMEINMGDELEFEVFRLDSDAAGVFCIRGKLNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGKSNFL
Protein: Probable protein phosphatase 2C 30 (OsPP2C30) (EC 3.1.3.16) (Q84JI0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Together with ABI5, PYL5 and SAPK2, is part of an abscisic acid (ABA) signaling unit that modulates seed germination and early seedling growth.
Subcellular location: Nucleus {ECO:0000269|PubMed:22071266, ECO:0000269|PubMed:26362328}.
Interaction partners:
- Serine/threonine-protein kinase SAPK2
- Abscisic acid receptor PYL5
- Abscisic acid receptor PYL10
- Abscisic acid receptor PYL9
- Serine/threonine-protein kinase SAPK6
- Serine/threonine-protein kinase SAPK3
- Serine/threonine-protein kinase SAPK10
- Serine/threonine-protein kinase SAPK9
- Os03g0297600 protein
- Serine/threonine-protein kinase SAPK1
Sequence:
MAEICCEVVAGSSSEGKGPECDTGSRAARRRRMEIRRLRVVAERGAEEETSGKRRRLDGGGGEASTDEEDREVERARYGFTSVCGRRRDMEDSVSACPGFLPGHHFFGVFDGHGCSHVATSCGQRMHEIVVDEAGAAAGSAGLDEEARWRGVMERSFARMDAEAVASSRGSVAPAPTCRCEMQLPKCDHVGSTAVVAVLGPRHVVVANCGDSRAVLCRGGAAIPLSCDHKPDRPDELERIHAAGGRVIFWDGARVFGMLAMSRAIGDSYLKPYVICDPEVRVMERKDGEDEFLILASDGLWDVVSNEVACNVVRACLRSSGRRERNRSSPTSNLSPRQSSSSGDEAPNDGAPSAAAGSESDEESAAEEDKACAEAAVLLTKLALARQTSDNVSVVVVNLRRRKL
Protein: Vacuolar basic amino acid transporter 4 (Q04602)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transporter required for vacuolar uptake of basic amino acids.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:19001347}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:19001347}.
Interaction partners:
- Vacuolar membrane protein YPL162C
- Vacuolar lysine transporter YPQ1
- Uncharacterized vacuolar membrane protein YML018C
- Low affinity ammonium transporter
Sequence:
MGKKDRQRKKLREFAKLKNRQRNLRKSVQTLKNEVQREAKVPRTSNQIALGNDKIEEINENSPLLSAPSKQEEVSIPKAVDIDTIDAQPLHEGPKIDDSPQDEVNSIKGKPADKANEDDLKPPSQHEACGNSALQSSITDFSDRSVSPLQSITSCNTPMSEHELPVSSSNSFERADDMPVVQADNQTSSSKSLHIVAPSPEVPVSGDEITSYGYGSIPQSIGDVENGLNPPYVENTSSDELVHDLTRRRIFSSCMCTYLFFIAMDSSIILVIASKIASEFHELWRLSLVISAYLLSNAIGQLVFLKLSLISSVKLLLCIAQFSFILGGYLSWSSAHFWTFIFARCVTGFGGGSLIALKSTIMNRFSQKNDSRYSLSASMITFAMGVVIGPFMMNLFDSSHGSGWRNAFLIPVPFCLVNASIMLADMYSVKSTLYGRPTPTLWKRFKNTLLSPDLYEILTLTLFLLCFVQVTSLDLTGLKNNTMIQALLFSVIIVCGILFFLIETSDTYMNSVISMSLQGDKRLIWTMIGISFCFAALMCIIPFGTTYFIIVLNLSTLQLAERLSPFFFSIVLGYFSVSYFWKSKGQNFLLKFVLSGATLLLYVALMGVSLNLPVWKQYICLSLPFLGSSMILTLLSNLYHEYHEQRKSPISGSIVYCFGAVGGTVGISLGGYVFHKTLIKLMHEKVMPFSKQGYLKKDLLKIIKHATESSDWVHESAPKFVFQTLIECYLQACRNVFKLSTLFFTITVVAIFIFNRIHCRSQNCLSLS
Protein: Auxin-responsive protein SAUR32 (Protein ABOLISHED APICAL HOOK MAINTENANCE 1) (Protein SMALL AUXIN UP RNA 32) (Q9ZUZ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in the apical hook development (Ref.6).
Subcellular location: Nucleus {ECO:0000269|Ref.6}. Cytoplasm {ECO:0000269|Ref.6}. Note=Primarily localized in the nucleus. {ECO:0000269|Ref.6}.
Interaction partners:
- Probable indole-3-acetic acid-amido synthetase GH3.1
- Auxin transporter-like protein 2
Sequence:
MGTGEKTLKSFQLHRKQSVKVKDVPKGCLAIKVGSQGEEQQRFIVPVLYFNHPLFMQLLKEAEDEYGFDQKGTITIPCHVEEFRYVQALIDGERSVYNGNNHHHRHGGRDQYHHLVGCFRA
Protein: U17-MYRTX-Tb1c (A0A6M6RA65)
Organism: Tetramorium bicarinatum (Tramp ant)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MEKNRTNIFSVYLMITFLLISIFITMVMSDGEATIIDVPIQCPPGKVKVGNRCRIVF
Protein: Intelectin 2 (Intelectin-2 precursor) (C1IHV0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Opioid growth factor receptor-like 2.
- Cytochrome b5 domain-containing protein 1
Sequence:
MGMAAFLTKMLLGFLFSVTLSLWFCEAKSMGAMYVIQETETPCINISDSNSNHELEKLLDRIKYIARSCKEIRDKYHVYEDGLYYLISSRGVLYQTFCDMTTAGGGWTLVASVHENNMYGKCTVGDRWSSEQGSNANRPEGEGTWANKVTFGAAEAATSDDYKNPGYFEIAAQDVSVWHVPNNMELEHWSTGSILRYHTENRFLTLHGGNLFSLFKKFPVRFGIGVCNTNNGPAAPIVYDTGNVDSTKTLYGPSTRSQFEPGFITFRVFNTEKAAMALCSGVKPIGCHTEYFCIGGGGHFPEGVPKQCGDFTGFDWNGYGTNTGNSASREIIEAAVLLFYR
Protein: Sr-CI (Q6V6S4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
EFFWTLAVIVIYCIGHIHGRCERSLDLDNGSINYRPRNIVRFRCNRGYTLQGTVMQTCDRDGRLRGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGAYGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVQLMTGSECGTNGFTTTTEPTAPTGSNEQPLVYDMMSCSGRCGTSMSASNITNNGIVMGCGCNDECLSDETCCLNYLEECTKELLTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTTTSTTTTKRPTTTTTTTKATTTKRTTTTKKPTTTSTTPKPTTTTSTTPKSXXXTTSTTSTTPTTTTTXXXXNVFTTKKTTTMIPTSSTEKTTDTNTTMKTRKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLGIVLVVVLANVVNRWIIPITGSKTSSEKAVRFKKAFDSLKKQRKRNS
Protein: DNA 5'-3' helicase (EC 5.6.2.3) (Q6TY79)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
AELQNLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMDTETPICQYFEGFSLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASVQRDTDMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITHFATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALMNYVKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHLVDSFCNLSTEEAVQLARRWLRRMAQPFTREDQLGISLLTLAQLENMEQEKLERQAQGKQGVGGEVQEL