Protein: Cadherin-3 (P34616)
Organism: Caenorhabditis elegans
Function: Cell adhesion protein involved in the control of epithelial morphogenesis. Together with metalloproteinase zmp-1 and hemicentin him-4, plays a role in anchor cell (AC) invasion during postembryonic vulval development.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15960981}; Single-pass type I membrane protein {ECO:0000305}. Basolateral cell membrane {ECO:0000269|PubMed:15960981}. Cell junction {ECO:0000250|UniProtKB:Q9BYE9}.
Interaction partners:
- Matrix metalloproteinase-A
- C-factor
- Transcription factor fos-1
- MMP-like protein
- Aminopeptidase N-like N-terminal domain-containing protein
- Glycine rich superfamily member
- Ig-like domain-containing protein
- Homeobox protein ceh-2
- Matrix metalloproteinase-C
- Zinc finger protein egl-43
Sequence:
MTIRIFFSIFLLNHLIFFHLFNFTHQFSEETIKFSVSEDAKLNTIIGHLEAEIGYTYRLSRGNSKIKFDEQTLELSVSSPLDRESENAIDMLIITSPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNFGIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEMFSISDENILVTQNNTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPSDYPFIIVQPEDVNGKTLAILSITDSDGPLGANSTIWIENGNEQSIFSLISRQSINILTVKHVENANQEQYILEFRANDGQSPADRITRKELKIFFKKYVKSTQIHVERESHVTVEKDTVPGSFVAHVETNCTDMCSFELANSDVFKIDPFNGIIVTSSILPEGVTSYHLPIRIHLPPPSTQLVEADVFVKVIQESVPKNLIRSSESPIHLKRAYTFTTWQDVSLGTVIGRLPKAQIYSTIDTVSELGVFPDGSVFVGKTITSDFVTLPVTLVNRNTTQTSIITLIVKPLNQHSPICQITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDVKNQKLQYHLLNYHDFFQLDKETGKVTTIQDVPMTWQRLNISISAVNMDSERFLQSKTFLLVTVTSSSKLAVQLNSGNLIRIFKNDKIGEKVGHLDIASSETVYWSTLDPRLHVDSSGNIILIRRNAKQASTGFDIILTSENGEKTEKVNFEVEFVDSERSEDVEKVMDIVLNENTTEVSNLMNDWKNWKISRVILENANNSGNNTFFLEHKKLWRTKNATVSNAYIILESEDQEGSPKSFKLLHVTTSPSPSSESSCISPAHLISPPSTVPLPSNCSNVKLQNLKTSLQIHENNLLIPTQSELINHVDLVSTQNSDMKPFMMTLIKDYLSEDVRFSTNNVLMLLSSIHPIGTSFGRVTAESGYRIRYYIVGTDKISIDADTGELILKERFYRNLNDILIVAVIPKGIAKAKITIEVIEDRLILPQSNFFIPSPPSFNSKSKIGKIPIDRDDVTIDVIDEHFYVRNFEIFVKRHFIPNSNFYDLKGTVKKGKLSAPISVTLFFGEKMKSREIRENELMFEIEENSPIGTVVGVVPNSDTTKYRLVDPTCGLLIDQEGIIRTTTVFDRENTSLLKTKMIEPSENRIWNLLIFIADVNDNKPKILNAPGRIIVYDDLNYKLEWEDLDAIASDVSFSIVDGDVFGNLEIEDSGVISLNSIPNESFNATIRIYDNRPPFKVHFDDVTIEFQVTQKLRAVTCEDAEFWMFFGNEDVGMLIASEIVTWRIVPQIGSDSFKIDPITGIIQSTPNTKPTSDIAKLKIQAISYDGERVGFCDVKIHIDKAAFVENVVLSNGTFEFNISETADRFTEVGKIVILGAGLEGSVFRIQDNDYNFTISPFDGTIFTNSPLDFENIKTYRFNITAGKSTSQVIIHVTDENDEAPRFITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTSLFAVNSTTGDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKDKDAELQYSLESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVKVTDGEKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVEIIHVINVHDLDKSDHLKFSLNNSNLNLSENGEITLKSPLQTAVPVRVTVSDDAGHVAFMEYLFHPHSRKHFPVFVEKLDTVSVREHDEQELAVFKANGDSIRYSIVSRCSDHLEMEKSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKLIGHVIARDIDRSSRVFYEIVGGDANHEFMVTESGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRIFHVEVPEDVRIGEPVIQLSASDADEHSNHRFELDGGGEGIPFRVDENTGMVFVNDSLDFEKKQSYRIKVKLTDGAWLIETSLFVNVKDVNDNAPIFEKPEYLFISEENSAEIGQFHASDMDSENNGKIRYSVTSPYFKIEPSTGVLSRFRQQLPQPLMSLKVTATDHGVPRLQKTVLAHLVDKSSFGKIKQRRIRETTKVGDVIGKKIDSGATIFPLDVATVTRDGDVVLKKNATQFWILENDTIYEFVKTDAMESTKNENITLNITSDISMNSDNFKVLRNGSLIVFGFSGNQAHLKIQCDDGFWPKQDRKIINLVVNNLDADRNSFPLARQPTIRKSMSLPKTMILNIPFDSPTGTIIWKNLENAVQYMENQKNVNFSNGSKNLILKTPLEETMQIDIFGQNFERSALTITPNRSLMACPVFQKNFYFFESVANLDSKHPTEIHNFGWSSDEIKGCQIDIFDKTHLFYQNGSSLIFLKPLLPGTYQFSLQIKSQSDSKIRSACHVVVTVIPPTNLTTWNIPSVIFATRNYNIPNLFHLPSGYSLSSDQRTFSLIGSGTGKNISKLSSGVYQVNVVGKDEKKEIVRILLDDVADDVTSKDIEYHVVSSTLSNLKIPTPIDVECFPRTEENLYEITKDCRLLFNSDVINTTIPVVTSPANSTWNLRIINESPETVKSLENNAVSLEIITQKSSIPRLITDLRVTYSDMKIYCLGTWQTSEDIKYHITFVIVDRNGVVIEESEARQTLTSFLKKHRPGYLDFVDFDKDPCDGVTCIQKNSTCQPTLVGDSASRLVSRSSSVIFDLPLKKLTARCFCSSGIDCYDDTTNETIQKTQKINVITTCDDIDCGPRGKCFMEESSQPICRCGQGFESMYSCERADDVFSMSTGGSVEISVRNGTSHLLKCSENCDGRDIQKIEFDFRTVQLEKSELFRVDFGKQVALIELIGGSLTFSITDAYARPIETRIEKRVNDGRWHRLLFQMSEDGRRISIQVNGRGKEVKSRVPLQMLFTAKKIQLMTPAAFCFRRLLAQNQFVHPILNRNKFFEISSTGTSRNECQFDSIQSGSGGFRLFSNFSNTTTLILLITLALISLIGFSVCLLAIRRRWRQKSPGDQKQTERSNGWTGHVMPRRRGHINRSMVKSPDDDTYDVATVYGMKSTSTDDITHIYTSSSSRRYQPPTAPSYRRDGHINMAYL