wanglab/gogpt-training-data huggingface dataset:
Protein: Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1) (P61619)
Organism: Homo sapiens (Human)
Function: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis. Plays a critical role in nephrogenesis, specifically at pronephros stage (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12475939, ECO:0000269|PubMed:27392076, ECO:0000269|PubMed:32325141, ECO:0000269|PubMed:32814900, ECO:0000269|PubMed:36261522, ECO:0000269|PubMed:8616892}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER). {ECO:0000269|PubMed:27392076}.
Interaction partners:
- Protein transport protein Sec61 subunit gamma
- Protein transport protein Sec61 subunit beta
- Translocation protein SEC62
- Translocation protein SEC63 homolog
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL18
Sequence:
MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
Protein: Uncharacterized protein (Q387B1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSHRISSTNNPFSERDFNLLKSGALEKSRSVVSRREQVWDNIVDVGEGVKANDVEELMARLEQHGLRRVLAENEGGTGALHAADGTHGTENCDTSTEDIDEDDSCEKRAPYYYMCVPCELSLTEISTKPATMRMLQDAHYHFSSAEHRCIASWMGVVDIEKTLAVTSRLEVGGYIRIFVNGIPFLISARPGGGGMFYPLPHETVEAREQSGRNAEPSKGTAVRKEIWYRPLQSVFTRCKQILYTAASRQKLRGESSPFRAQRRNGIVLLHIPMKTYERESFIRGPSVPALFEVQRERVSNKKRRHKENGTRTCYVMREKPIAAWEDEDDSTDAISKVTVKEEGVYRLVLLCSDDVRRSMRQAEEEEHEPETRVSGEVTHPLTVEALQMIGGTTREESNQSDGKSLSYDSSSWSRKT
Protein: Membrane progestin receptor alpha-B (mPR alpha) (Progestin and adipoQ receptor family member VII, b) (Q801G2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Steroid membrane receptor. Signals upon progestin binding, resulting in rapid activation of MAPK and down-regulation of adenylyl cyclase activity. Interacts with steroids with varying degrees of affinity, showing specificity for activation by the maturation-inducing steroid (MIS) 4-pregnen-17,20beta-diol-3-one (17,20beta-DHP). Capable of mediating progestin-induced oocyte maturation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16899559}; Multi-pass membrane protein {ECO:0000269|PubMed:16899559}.
Interaction partners:
- Membrane-associated progesterone receptor component 2
- Membrane-associated progesterone receptor component 1
- Progesterone receptor.
Sequence:
MATVVMEQIGRLFINAQQLRQIPRFLESAFPKLPCTVMVSDVPWVFRESHIITGYRPPDQNWRYYFLTLFQRHNESVNVWTHLLASLIILVKFQELSETVDFLRDPHAQPMFILLLAAFTYLGCSALAHLLSAKSEISHYTFYFLDYVGVAVYQYGSALAHFYYVVEEEWHAQVRTFFLPASAFLAWLSCTGCCYGKYASPKLPKFVHKLFQVVPSGLAYCLDISPVLHRIYRCYSSEHWCADQAVVYHCYQVLFFLISAYFFSYPHPERWFPGRCDFIGQGHQIFHVFLVLCTLVQIEAVRLDYTERRRLYEHLHGDLAHDAVALFIFTACCSALTAFYVRKRVKTYLEEKQE
Protein: Peroxisomal hydratase-dehydrogenase-epimerase (HDE) (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.119); (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12)] (Q02207)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase-epimerase activities. Converts trans-2-enoyl-CoA via D-3-hydroxyacyl-CoA to 3-ketoacyl-CoA.
Subcellular location: Peroxisome.
Interaction partners:
- Acyl-coenzyme A oxidase
- 3-ketoacyl-CoA thiolase, peroxisomal
- Small ribosomal subunit protein mS47
- Carnitine O-acetyltransferase, mitochondrial
- 3,2-trans-enoyl-CoA isomerase
- Long-chain-fatty-acid--CoA ligase 2
- Peroxisomal long-chain fatty acid import protein 2
- Acetyl-coenzyme A synthetase 1
- Isocitrate lyase
- Peroxisomal catalase A
Sequence:
MPGNLSFKDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGTLGGSGHNSKAADLVVDEIKKAGGIAVANYDSVNENGEKIIETAIKEFGRVDVLINNAGILRDVSFAKMTEREFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTENVLPPHILKQLGPEKIVPLVLYLTHESTKVSNSIFELAAGFFGQLRWERSSGQIFNPDPKTYTPEAILNKWKEITDYRDKPFNKTQHPYQLSDYNDLITKAKKLPPNEQGSVKIKSLCNKVVVVTGAGGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEINKLYGEGTAIPDSHDVVTEAPLIIQTAISKFQRVDILVNNAGILRDKSFLKMKDEEWFAVLKVHLFSTFSLSKAVWPIFTKQKSGFIINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAPHAETAMTKTIFSEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLFEVGGGWCGQTRWQRSSGYVSIKETIEPEEIKENWNHITDFSRNTINPSSTEESSMATLQAVQKAHSSKELDDGLFKYTTKDCILYNLGLGCTSKELKYTYENDPDFQVLPTFAVIPFMQATATLAMDNLVDNFNYAMLLHGEQYFKLCTPTMPSNGTLKTLAKPLQVLDKNGKAALVVGGFETYDIKTKKLIAYNEGSFFIRGAHVPPEKEVRDGKRAKFAVQNFEVPHGKVPDFEAEISTNKDQAALYRLSGDFNPLHIDPTLAKAVKFPTPILHGLCTLGISAKALFEHYGPYEELKVRFTNVVFPGDTLKVKAWKQGSVVVFQTIDTTRNVIVLDNAAVKLSQAKSKL
Protein: CD74 antigen (CD74 molecule, major histocompatibility complex, class II invariant chain) (Q764N1)
Organism: Sus scrofa (Pig)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MEDQRDLISNHEQLPMLGQRPGAPESKCSRGALYTGFSVLVALLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLESLRMKLPKPSKPLSKMRVSAPMLMQALPMEGPEPMRNATKYGNMTQDHVMHLLLKSDPLGVYPKLKGSLPENLKHLKNTMDGVNWKLFENWLRQWLLFEMSKNSLEETPFEVPPKDPLETEDLSSGLGVTKQDLGQVIL
Protein: Heat-inducible transcription repressor HrcA (P25499)
Organism: Bacillus subtilis (strain 168)
Function: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.
Interaction partners:
- Chaperone protein DnaK
- Protein GrpE
- Chaperone protein DnaJ
- Transcriptional regulator CtsR
- Chaperonin GroEL
- ATP-dependent Clp protease proteolytic subunit
- Negative regulator of genetic competence ClpC/MecB
- Co-chaperonin GroES
- ATP-dependent Clp protease ATP-binding subunit ClpE
- Protein-arginine kinase
Sequence:
MLTNRQLLILQVIINDFIKSAQPVGSRTLSKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRYYVDHLLSPVKLTKSDLDQIHSIFKEKIFELEKTVQKSAQILSDLTNYTSIVLGPKLSENYLKQIQIIPIQPDMAVAILVTNTGHVENKTINFPTKMDLSDIEKLVNILNDRLSGVPMDELNERIFKEVVMYLRQHIKNYDNILDALRSTFHSTNHVEKLFFGGKINMLNQPEFHDITRVRSLLSLIEKEQDVLKLVQSPHTGISIKIGKENDYEEMENCSLITASYSVDQKQIGSIAIIGPTRMNYSRVVSLLQHVTSDLSKALTSLYDE
Protein: Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2) (Q8CFC2)
Organism: Mus musculus (Mouse)
Function: Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- E3 ubiquitin-protein ligase HERC2
Sequence:
MSSESDDKRARTRSKTLRGPPETTGADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEDAETEHLVSKRKSHPLRLALDEGYRMDSDGSEDAEVKDVSVSDESEGPLEEAEAEMSGQEEIHHPQTAEGKSLIKPHFDSNPTSSPSGFSKSSYSSYQGIIATSLLNLGQIAEEALVKEDSVSVAKLSPTVVHQLQDEAAMGVNSDEGEKDLFIQPEDVEEVIEVTSERSQEPCPQSLKDMVSEESSKQKGVLGHEEEGEEEEEDEEEEDEEEEEEGEEGEEEEEEEEEEEEEEDEEEEEEEEEAAPNVIFGEDTSHTSVQKASPEFRGPELSSPKPEYSVIVEVRSDDDKDEDSRSQKSAVTDESEMYDMMTRGNLGLLEQAIALKAEQVRAVCESGCPPAEQGHLGPGEPGKMAKPLDVVRKSCYSKDPSRVEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQLQTGDPPKNNSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSHDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKAVDIEVDENGTLDLSMHKHRKRENTFPSSSSCSSSPGVKSPDVSQRQSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGLKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGALNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEILSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVNTLTDMYSNQDCYQNPENKGLLETIKQAVRGIQV
Protein: Protein JAZ13 (Jasmonate ZIM domain-containing protein 13) (F4J078)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Non-TIFY functional repressor of jasmonate (JA)-mediated growth and defense responses. Intrinsically resistant to JA-induced turnover, probably due to the absence of the canonical degron that strongly interacts with COI1 in the presence of JA-Ile in the TIFY/JAZ proteins.
Interaction partners:
- Transcription factor MYC2
- AFP homolog 2
- Coronatine-insensitive protein 1
- Protein TIFY 10A
- Protein TIFY 9
- Protein TIFY 5A
- Protein TIFY 5B
- Protein TOPLESS
- Protein TIFY 11B
- Protein TIFY 6B
Sequence:
MKGCSLDLHLSPMASTLQSCHQDSTVNDRSSTIRSKEINAFYSGRLSEYDLVEIQMRAIIEMASKDREVTALELVPVRLESPLGCSVKRSVKRFLEKRKKRSKSFTLTPNYTSSTSSSSSSLHNF
Protein: Klra19 protein (Lectin-related NK cell receptor LY49S) (Q9JHV3)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MSEPEVTYSTVRLHKSSGLQKLVRHEDTEGPREAGYRKCSGSWQLIVKALGILCFVLLITVAVLAIKIFQYGQHKQEIHEPLNYHHNFSNMQSDFNLKEEMLTNKSIDSRSGNELLESLNREQNRGYSETKTDVDSSQDTGTGVKYWFCYQTKCYYFIMNKNTWSGCKQNCQYYSLPLVKIADENELKFLQFQVIPDSYWIGLSYDKKKKQWAWIENGQSKLDMKIRKMNFKPEGCVLLSKRRLEDTNCNNSHYCICGKKLDKFPH
Protein: Probable L,D-transpeptidase YnhG (EC 2.-.-.-) (P76193)
Organism: Escherichia coli (strain K12)
Function: Responsible, at least in part, for generating a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link.
Subcellular location: Periplasm {ECO:0000305}.
Interaction partners:
- Probable L,D-transpeptidase YcbB
- Putative L,D-transpeptidase YafK
- Penicillin-binding protein 1B
- D-alanyl-D-alanine carboxypeptidase DacD
- D-alanyl-D-alanine carboxypeptidase DacC
- Serine/threonine kinase YeaG
- D-alanyl-D-alanine carboxypeptidase DacB
Sequence:
MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTVQEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNLAELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLERGIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIKALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQFKDNKAVDQKLVDKALYRRAGYPVSVSSGATPAASNAPSVESAQNGEPEQGNMLRVTQ
Protein: Ab2-450 (Morf4 family associated protein 1) (Q7TP34)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MGLLRWLPLLGQLLLLWPLAARPASPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTTVVEELVRGRQRRFIAVEQEFFRLWWDGVASEQQKQQTAHAEDSEEPPGAHHLRVPAMGDCCIDSQMWSGNYFMGLQFMNKQVRQLLDEGRLEFVLGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLISRIDYDLKDAMQEAQQHVALVAPGLGDSNRGGDTRSLRKKPKGLQFVWHGSPSLSEQQEIYTHVMDLYSYCTPSHIPFSNRSGFYWNGVAVFPEPPPDGVYPNMSEPVTVDNIHLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFDNMDPLLEYINNRSAQFGISVQYATLNDYFQALHDFNVTWDIRDHHDFLPYSSGRSEDTASAPWLVEVWEPSSLAVGTLMVLLYQAGTVTPPVPTRSAPRYREGTQLPYHQAEPQQAWTGFFTSRSTLKGLARQASALLYAGESMFTRYMWPHPRGTLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVKNMYMEHLSMGMRGVHKLMASIALDRPPGSGTDTRPVGYSASVYNPLAWKITTIITLTVAFPSVSVTDELGRPVSAQCTYAKVLSVLKTHCNRGAKVGIQNSTKDPSAYDLLILTTIPGLSYRHYKVRRTRGDQAGTRELVTPRANTLKFSRKLRNQTSQEGKLLVPVMNDCYTLLFDQDTNMLHSIQDRQSNRTVHMTQEFLEYRANGDVKQGPISDNYLFASNDTAEPSWEAVGMEMVVGTLATDVRQYFYRNITDQGYIYSIHTRLAHVHPSLAGELLCRRIEQQYQVGPLDLNREAILRTSSDLNSQQVLYSDNNGYQMQRRPYKAFKSNPIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQENGQVEVREAWLSPYGPSKPPAAGPEPRKDRFPQVMLHRRLWNNLVWDLNYNLTLNDTSVVHPVLWLLLGPKSTTTALRPRSGVALQHRPVVLLKELTDEEETAIHRPHHPWPVTLPPSLHLQVLSLPGWQYSRNHAQHLKNLQRGSLPAAPSTSSPLTLSTGCREFRWFIQQMPLEGVGVLGSLVLSLLDSEDDGKGSRHDGGHPEKPQVNLQRVLLRLHHLYEAGEDPIALRGLGSVVAVEERSLTGTWDVQTLQRWHWRTKIGQLKGHPGSNQHPKTQALTTVVPKNNCQVETSGFFGKLPFLGLGNSSEVIDLTGMCQVLASLHNIRKKEEDEDEEEEEEEEEEESRRKERAARLRGFSEAESWNSGGSFEDSARARSLSVVQTSKAAEMRPLDAVELAEPEEVEVLEPEEDFEQFLLPVIHEMREDIASLTRERGRAPVRNRGKLWEMDNMLIQIKTQVEASEESALNHLQGAGGAEPRGPRAEKADEKAQEMAKMAEMLVQLVRRIEKSESS
Protein: MBL-associated serine protease 1 (Mannan-binding lectin serine protease 1 isoform 1 precursor) (X1WH68)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Complement component 1, r subcomponent
- Zmp:0000000729.
- Plasma protease C1 inhibitor isoform X1, member 1)
- Complement C4-B isoform X1
- Collectin-11
Sequence:
MELTRVFVILAQCVWPLWTQVIPLSDMYGTIKSPNFPEPYPKETDLQWNITVPDGYQIRLYFMHFDIEPSYLCEYDYLKVYSDIEELAVFCGREKTDTERVPASDIILSPGNVLSVAFRSDFSNEERYFGFEAHFSAIDVDECRDRNDEDLVCDHFCHNYIGGFYCSCRFGFLLHSDNRTCKVECNKNVYTERSGEITSADFPKAYPKSSECKYSIELEEGFQVSLEFDDTFDIEDHPEVSCPYDFIKIQAGEKEFGPFCGEKSPGKIQTGSNIVNILFHSDNSGENLGWKLTYTSTGPECSPPTPLLNGQLEPLQPIYIFRDHITLTCDPGYLLRQGDEEFEHYQIECLRDGKWSSGVPLCKKVDCGPVDELLAEVVFVNSDNSTVFGSQIQYSCRDSAVNNTYTCNQSGIWLSDDGMPLPSCLPGVIEGNLSRPAGPESPTPLASTPLACGEQSQPFPAHQKRIVGGRPASPGLFPWQVLLSVEDVYRVPVVRWFGSGALLSPLWIVTAAHVLRSHRLDLSVVPVDPEHIQVHLGLTDVRQKHLATNRSVEKIILHPQFDPQNYNNDIALVKLNQEVALSALVRPVCLPRPGLDSQVLTPNTLGIVAGWGINAANASASSSGLTSDSSSVSELLQYVKLPVVSQDECEASYASRSVNYNITGNMFCAGFYEGGQDTCLGDSGGAFVTQDGRSGRWVAHGLVSWGGPEECGSQRVYGVYTRVANYLQWLHTHMDAERWW
Protein: Annexin (Q8W4Z7)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
VIRIATTRSKAQLNATLNHYNTAFGNAINKDLKADPEDEFLKLLRAAIKCLTVPEKYFEKVLRQAINKLGTDEWALTRVVATRAEVDMVRIKEEYQRRNSVTLEKAIAGDTSGDYEKMLLALIGAGDV
Protein: Transcription factor bHLH100 (Basic helix-loop-helix protein 100) (AtbHLH100) (bHLH 100) (Transcription factor EN 7) (bHLH transcription factor bHLH100) (Q9ZVB5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in metal homeostasis. Confers tolerance to high zinc (Zn) and nickel (Ni).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor bHLH47
- Fe
- Ferric reduction oxidase 2
- Transcription factor bHLH104
- Transcription factor ILR3
- Transcription factor bHLH115
- Transcription factor bHLH34
- Probable nicotianamine synthase 4
- Ferric reduction oxidase 3, mitochondrial
- Transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR
Sequence:
MCALVPPLYPNFGWPCGDHSFYETDDVSNTFLDFPLPDLTVTHENVSSENNRTLLDNPVVMKKLNHNASERERRKKINTMFSSLRSCLPPTNQTKKLSVSATVSQALKYIPELQEQVKKLMKKKEELSFQISGQRDLVYTDQNSKSEEGVTSYASTVSSTRLSETEVMVQISSLQTEKCSFGNVLSGVEEDGLVLVGASSSRSHGERLFYSMHLQIKNGQVNSEELGDRLLYLYEKCGHSFT
Protein: U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 (EC 2.1.1.-) (THUMP domain-containing protein 2) (Q9BTF0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:34948388}.
Interaction partners:
- Son of sevenless homolog 1
Sequence:
MSEARGEPGSGPEAGARFFCTAGRGLEPFVMREVRARLAATQVEYISGKVFFTTCSDLNMLKKLKSAERLFLLIKKQFPLIISSVSKGKIFNEMQRLINEDPGSWLNAISIWKNLLELDAKKEKLSQRDDNQLKRKVGENEIIAKKLKIEQMQKIEENRDCQLEKQIKEETLEQRDFTTKSEKFQEEEFQNDIEKAIDTHNQNDLTFRVSCRCSGTIGKAFTAQEVGKVIGIAIMKHFGWKADLRNPQLEIFIHLNDIYSVVGIPVFRVSLASRAYIKTAGLRSTIAWAMASLADIKAGAFVLDPMCGLGTILLEAAKEWPDVYYVGADVSDSQLLGTWDNLKAAGLEDKIELLKISVIELPLPSESVDIIISDIPFGKKFKLGKDIKSILQEMERVLHVGGTIVLLLSEDHHRRLTDCKESNIPFNSKDSHTDEPGIKKCLNPEEKTGAFKTASTSFEASNHKFLDRMSPFGSLVPVECYKVSLGKTDAFICKYKKSHSSGL
Protein: TOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B) (Q9Y4F4)
Organism: Homo sapiens (Human)
Function: Involved in ciliogenesis. It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length. Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4 (By similarity).
Subcellular location: Cell projection, cilium {ECO:0000250|UniProtKB:Q6A070}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q6A070}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:32453716}. Note=Detected along the length of primary cilia and at the basal body. Colocalization with the cytoplasmic microtubule cytoskeleton upon heterologous expression is most likely an artifact. {ECO:0000250|UniProtKB:Q6A070}.
Interaction partners:
Sequence:
MAAAPSALLLLPPFPVLSTYRLQSRSRPSAPETDDSRVGGIMRGEKNYYFRGAAGDHGSCPTTTSPLASALLMPSEAVSSSWSESGGGLSGGDEEDTRLLQLLRTARDPSEAFQALQAALPRRGGRLGFPRRKEALYRALGRVLVEGGSDEKRLCLQLLSDVLRGQGEAGQLEEAFSLALLPQLVVSLREENPALRKDALQILHICLKRSPGEVLRTLIQQGLESTDARLRASTALLLPILLTTEDLLLGLDLTEVIISLARKLGDQETEEESETAFSALQQIGERLGQDRFQSYISRLPSALRRHYNRRLESQFGSQVPYYLELEASGFPEDPLPCAVTLSNSNLKFGIIPQELHSRLLDQEDYKNRTQAVEELKQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTLEVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQQVLCLLLEHLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFAVLASSMGSGKTSILFKAVDTVELQDNGDGVMNAVQARLARKTLPRLTEQGFVEYAVLMPSSAGGRSNHLAHGADTDWLLAGNRTQSAHCHCGDHVRDSMHIYGSYSPTICTRRVLSAGKGKNKLPWENEQPGIMGENQTSTSKDIEQFSTYDFIPSAKLKLSQGMPVNDDLCFSRKRVSRNLFQNSRDFNPDCLPLCAAGTTGTHQTNLSGKCAQLGFSQICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAKVSISKSTYNKMRQKRKEEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPTGAISQYKERMPSVTHSPEIMDLSELRPFSKPEIALTEALRLLADEDWEKKIEGLNFIRCLAAFHSEILNTKLHETNFAVVQEVKNLRSGVSRAAVVCLSDLFTYLKKSMDQELDTTVKVLLHKAGESNTFIREDVDKALRAMVNNVTPARAVVSLINGGQRYYGRKMLFFMMCHPNFEKMLEKYVPSKDLPYIKDSVRNLQQKGLGEIPLDTPSAKGRRSHTGSVGNTRSSSVSRDAFNSAERAVTEVREVTRKSVPRNSLESAEYLKLITGLLNAKDFRDRINGIKQLLSDTENNQDLVVGNIVKIFDAFKSRLHDSNSKVNLVALETMHKMIPLLRDHLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVQALSQHVDNYLLLQPFCTKAQFLNGKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMTNSGSLPGAGGNIRTATAKLSKALFAQMGQNLLNQAASQPPHIKKSLEELLDMTILNEL
Protein: Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (Q54TY4)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Probable methionine--tRNA ligase, cytoplasmic
- lysine--tRNA ligase
- proline--tRNA ligase
- Probable glutamate--tRNA ligase, cytoplasmic
- Probable glutamine--tRNA ligase
- arginine--tRNA ligase
- Probable isoleucine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Prokaryotic-type class I peptide chain release factors domain-containing protein
- ATP synthase subunit alpha
Sequence:
MTTPAPAPAKQPAKQAPAKKNDEEDFDPSMYKENRTKQLTSADIGVNPWPHKFEVSHQLPKFVEEFSVLEKDGEPSTQVVSIAGRVLSKRAAGSGLVFYDITGEFNKVQVLVNKRAYASCEEDYVKINGLLRRGDIIGAKGTPGRSKTGELSLFATEVILLSPCLHMLPKAASGLTDPETRFRQRYLDMICNESVKKNFIIRSKVIQGVRRYLDNLGFIEVETPMMNMIAGGAAAKPFLTHHNALNMDLFMRIAPELYLKQLVVGGMDRVYEIGKQFRNEDIDHTHNPEFTTCEFYMAYADYNDLYTMTEQLLQSIVMSIHGSLKIKYHPDGPSGKEIEIDFSSPWRKIDMIADLEAIIGEKIPTPYTSEECREFLVKTCRERKVECSAPQTTARLLDKLVGEYLEVQCINPTFIINHPEIMSPLSKYHREKPQLTERFELFVNTKEICNAYTELNNPFVQIERFAEQAKAKAAGDDESMLIDKVFTTSLEYGLPPTGGFGLGIDRFAMLMSDTYNIKEVILFPAMKPEQVSKPVTTTTAAPTTTEAPKSN
Protein: Developmentally-regulated G-protein 2 (AtDRG2) (Developmentally-regulated G-protein 2B) (AtDRG2b) (Q9CAI1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds GDP and GTP, and has low GTPase activity.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- UPF0235 protein At5g63440
- Ubiquitin-conjugating enzyme family protein
- Zinc finger CCCH domain-containing protein 21
- Cysteine proteinase RD21A
- At1g09850
- Probable cysteine protease RD21B
- Phosphoglycerate mutase family protein
- Probable cysteine protease RD21C
- DEAD-box ATP-dependent RNA helicase 16
- Protein ILITYHIA
Sequence:
MGIVERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGSSGGGDGFEVTKYGHGRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEGASEGKGRGRQVIAVAKSSDLVLMVLDASKSEGHRQILTKELEAVGLRLNKRPPQIYFKKKKTGGISFNTTTPLTRIDEKLCYQILHEYKIHNAEVLFREDATVDDFIDVVEGNRKYIKCVYVYNKIDVVGIDDVDRLARQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKPQSQQPDFDEPFVLSADRGGCTVEDFCNQVHRTLVKDMKYALVWGTSARHYPQHCGLFHHLEDEDVVQIVKKKVREEGGRGRFKSHSNAPARIADREKKAPLKQ
Protein: Phosphate-specific transport system accessory protein PhoU (Pst system accessory protein PhoU) (Negative regulator of Pho regulon) (P0A9K7)
Organism: Escherichia coli (strain K12)
Function: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. Encoded together with proteins of the phosphate-specific transport (Pst) system in the polycistronic pstSCAB-phoU operon. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex. Is also part of complex networks important for bacterial virulence, tolerance to antibiotics and stress response.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:3536855}.
Interaction partners:
- Phosphate import ATP-binding protein PstB
- Phosphate transport system permease protein PstA
- Phosphate transport system permease protein PstC
- Phosphate-binding protein PstS
- Phosphate regulon transcriptional regulatory protein PhoB
- Phosphate regulon sensor protein PhoR
- Low-affinity inorganic phosphate transporter PitB
- Alkaline phosphatase
- Elongation factor Tu 2
- Uncharacterized protein YaeQ
Sequence:
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYREDKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDSDK
Protein: Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) (O35157)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MLRLSLPPNVSMGFRLVALVALLFSHVDHITADTEAETGGNETTECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSRIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGDLSTTVFVDFRTEDGTANAGSDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILESNHASSIACLGSPSTATITIFDNDHTGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGVPEFQNDEIVKTISVKVIIDDEEYEKNKTFIEIGEPRLVEMSEKKALLLNELGGFTLTGKEMYGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEDQERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGERDDDDEYGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAICHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGAIFGMSIIL