Protein: Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) (Q9ESE1)
Organism: Mus musculus (Mouse)
Function: Involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:11254716}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:11254716}; Single-pass membrane protein {ECO:0000255}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:11254716}; Single-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:11254716}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cytotoxic T-lymphocyte protein 4
Sequence:
MASEDNRAPSRPPTGDDGGGGGKEETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGESIMCMVELLEKCDVTCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDSMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDKGQWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIARWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFVGGCLIITSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQMTAVYLFSDALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHKLLLYDGKLSSAIAFMYNPRATDAQLCLESSPKDNPSIFVHSPHALMLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYKQYLSDEVDLTICTTLLAFIMELLKNSIAMQEQMLACKGFLVIGYSLEKSSKSHVSRAVLELCLAFSKYLSNLQNGMPLLKQLCDHILLNPAVWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVNPQDRSGITPKGLDGPRPNQKEILSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMAEHPNSMIPAFDQRNGLRVIYKLLASKSEGIRVQALKALGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTMYNVLFEILIEQICTQVIHKQHPDPDSTVKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYHAVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREEQRKGDEETGPCSSSLVPEGTGATRGVDVSVGSQHEDRKDSPISPHFTRNSDENSSIGRASSIDSASNTELQTHDMSSDEKKVERENQELLDQATVEETATNGAKDDLETSSDAAEPVTINSNSLEPGKDTVTISEVSASISSPSEEDAAEMPELLEKSGVEEKEDDDYVELKVEGSPTEEAGLPTELQGEGLSVAASGGREEPDMCGHGCEVQVEAPITKIHNDPETTDSEDSRFPTVATAGSLATSSEVPVPQATVQSDSHEMLDGGMKATNLAGETESVSDCADNVSEAPATSEQKITKLDVSSVASDTERFELKASTSTEAPQPQRHGLEISRQQEQTAQGTAPDAVDQQRRDSRSTMFRIPEFKWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDNVIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKNMSSGGILRQCLRLVCAVAVRNCLECQQHSQLKARGDTAKSSKTIHSLIPMGKSAAKSPVDIVTGGISSVRDLDRLPARTWTLIGLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDILEPQDERHSQSLKETSSDNGNASLPDAENTPAEFSSLTLSSVEESLEGTSCTRRRDSGLGEETASGLGSGLSVASPAAPLGVSAGPDAISEVLCTLSLEVNKSQETRIDGGNELDRKVTPSVPVSKNVNVKDILRSLVNMPADGVTVDPALLPPACLGALGDLSVDPPMQFRSFDRSVIIATKKSSVLPSALTTSAPSSAVSVVSSVDPTHASDTGGESPGSRSPKCKTALSCKQLAPSHKTPAAHMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAEFILSRQRAEDIHRHAEFESLCAQYSADKREEEKMCDHLIRAAKYRDHVTATQLIQKIINLLTDKHGAWGSSAVSRPREFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHAADEDILAKGKQSIKSQALGNQNSENEALLEGDDDTLSSVDEKDLENLAGPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLATPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPSNFRDLSKPIGALNPKRAAFFAERFESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSVSRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQASPLMFTDQAQQDVIMVLKFPSNSPVTHVAANTQPGLAMPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIACGTGTHRRQVTDLLDQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKSSGIGDNPGGETATPRAILTGHDYEITCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGCFCTFSVNGKLQATVETDDHIRAIQLSRDGQYLLTGGDNGVVIVRQVSDLKQLFAYPGCDAGIRAMALSFDQRCIISGMASGSIVLFYNDFNRWHHEYQTRY