wanglab/gogpt-training-data huggingface dataset:
Protein: Amino-acid permease GAP1 (Q5AG77)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Amino-acid permease that coordinates external nitrogen source response and morphogenesis. Is capable of transporting several structurally unrelated amino acids such as leucine and phenylalanine, though with a lower capacity than the GAP2 and GAP6 permeases. Has citrulline import activity. GAP1 is also able to transport thialysine, and thus probably also lysine. Functions as a sensor via detection of some amino acids including methionine, leading to a rapid activation of trehalase, a downstream target of PKA.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21764911, ECO:0000269|PubMed:28028545}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Eukaryotic translation initiation factor 2 subunit alpha
Sequence:
MLHKKETNDTFVQLNRSPSTGEQKSSGIWSSIKDSFKPALPQDKLTGVDDIPDRELTDIERININAANSNLQRKLKTRHLQMIAIGSSIGTGLFVGTGGALSTGGPAAIVLAWAISAISVFMTMQGLGELAVAFPVSGGFNLYASKFLEPGIGFAVGWNYFLQFFVLLPLELVAGAITIKYWNASINSDVFVIIFWFVVLVITMLGVRWYGEAELVFCTIKVIAVIGFIILGIVLICGGGPNHEFIGGKYWREPGPFANSFKGFASSLITAAFSFGGTEMIALTASESSNVRHALPKAIKQVFWRIVIFYLGSIIMIATLVPYNDKRLLGSSSVDVTASPFTIAIVNGGIKGLPSVINAVILISVLSVGNASVYATSRTLNSLAEQGMAPKWTGYIDRAGRPLFAILITNVFGLFALIAADNEKQVVAFNWLLALSGLSSIFTWMSINLSHIRFRRAMKVQNRSLTELPFVAQSGVWGSYFGLTLNILYLIAQFYIGLFPVGGKPNAYDFFLAYLGVPVILASWIGYKIWKRDWTLFIRAKDIDLDTGRINVDLDLLQQEIAEEKAQLAEKPFYIRIYRFWC
Protein: dTDP-4-amino-4,6-dideoxygalactose transaminase (EC 2.6.1.59) (P27833)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.
Interaction partners:
- dTDP-fucosamine acetyltransferase
- dTDP-glucose 4,6-dehydratase 2
- UDP-N-acetyl-D-mannosamine dehydrogenase
- UDP-N-acetylglucosamine 2-epimerase
- Glucose-1-phosphate thymidylyltransferase 2
- TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase
- Lipid III flippase
- dTDP-glucose 4,6-dehydratase 1
- UDP-N-acetyl-D-mannosaminuronic acid transferase
- dTDP-4-dehydrorhamnose 3,5-epimerase
Sequence:
MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFGSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMSTYKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGEHFGEFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS
Protein: MYB-like transcription factor TCL2 (Protein CAPRICE-like MYB4) (Protein TRICHOMELESS 2) (B3H4X8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: MYB-type transcription factor involved in trichome cell specification. Acts as a negative regulator of trichome patterning and formation. May function by suppressing the expression of GL3.
Subcellular location: Nucleus {ECO:0000269|PubMed:22168948}.
Interaction partners:
- Transcription factor GLABRA 3
- Homeobox-leucine zipper protein GLABRA 2
- Transcription factor EGL1
- Uncharacterized protein At2g30430
- Zinc finger protein 8
- Protein TRANSPARENT TESTA GLABRA 1
- Zinc finger protein GIS2
- Protein TORMOZ EMBRYO DEFECTIVE
- Transcription factor MYC1
- Protein ABIL3
Sequence:
MDNTNRLRHLRSRKQSKFTLGDTAEVNSVKWEFINMTEQEEDLIFRMHRLVGDRWDLIAGRVVGREAKDIERYWIMRNCDHCSHKRRRVHKFYRFSISPP
Protein: Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9) (P48067)
Organism: Homo sapiens (Human)
Function: Sodium- and chloride-dependent glycine transporter. Essential for regulating glycine concentrations at inhibitory glycinergic synapses.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P28572}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- High mobility group nucleosome-binding domain-containing protein 3
Sequence:
MSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPSTSLAESVLKVWHGAYNSGLLPQLMAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI
Protein: Transcription factor AP-2-epsilon (AP2-epsilon) (Activating enhancer-binding protein 2-epsilon) (Q6VUC0)
Organism: Homo sapiens (Human)
Function: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q6VUP9}.
Interaction partners:
Sequence:
MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSVGSGHGETKASEKDAKHRK
Protein: PDGF- and VEGF-receptor related, isoform O (EC 2.7.10.1) (M9PCJ1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MAMLPRLILLPLLLILRISWSDAVPLQQFSPDPDDSIENCGGENGAPLMTPCKSAIILDAQTSTTLKCEDDEPMSWWTSQSQYVHVKSFDNTEDPARPFGTSLHLIEVTADYVAAYYCVKTSKFSQIAKEEQSDEAMIELVNQGYASSIYVYVNDPDTKLVDSHNVVTARQYTDVVIPCKPAMPDTEVLLETSNGESTWKISSKGQIQGNPKFFDSVRYHPRWGFTFRVIDCVSGYLYCKTLDYELIIDVTYPENGKPLPKPVIRSSVEHHVFTDTNFTLDCEQSAYVESVYGMEWFTPSRDENRIFASQSRTDPKTRNSTHQTGRSTLTVLNAQPSDTGLYKCVTTDNSNQNVQRATYRIKVLKQNESYLNVGEPSGHYNVQEYANRTIQMTANFEGFPTPSFSWFKPDGTEVRQSENNFKILSTELSTMLQVLNAQLQDSGTYVLRGSNSFGVVQREYNVSVMDAPALKMSDAYVQVGSVARLECTVRSYPPAIVTFFFRPCSLEPQWPTCSVLNQNFSFQTRPRPGKLSVERIYEVSFLPTEPGILTCIAQNIIDGKERRTLTKAHVLLGNISENMTIYGFDKDHKIAKEDNVNFTCEALAYHFDGNLKWFINGEDLKESDSVHIETSHTKYSYKSTVHITTISDRDRGTYECRAYHNDKDAVYSSREIDLYVHDPSAPQWTNGGQEGHSKIKRKLSQTLELECASTAVPVAIVRWFKDDKEVTESKLRHIIEKESKLLITHLYPGDEGVYKCVVENRLDRIERSFTVVISDLPGISMAWVWFGVILFLILIGLCVFLAVRYQKEHKRHLALKAAGLANFEEGAVGHINPDLTLDEQAELLPYNREFEFPRENLKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVVRALVSELKIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPDTDHIDPSIMTQRMSDNYELHRDTNGGGLKYANVGFPIHSYINEPHNNNTQPPTHRRNSDNDPRSGTRAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTVDLISWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELYEIMLECWRKNPESRPLFAELEKRFANMLGEDVASHYLDLNNPYMQSNIEYMKKQSTDYLALMGSPDELAPAAPRYVNGHIVPDIRIEELPDDYMEMSRDSDPDACTAIFSPTRLEGESSDFPDFSSETTFNFPGARQSPTLSNNLNSGSSKPLRKKNGMPTVDVADQAPEEIPMLHRSSTGSDGSPEQGRRFNQALKQQYVTPTPSPRHHVETKLNGEPSENYVNMKPPRKNIPGKTTTGGGGAAAGASTEAFSNPSYQPLSTVNEKEQRRY
Protein: Uncharacterized membrane protein C17A2.10c (O13760)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MTCVNVCFFLFPPCHRNKITEADKSLVDLLIPSLCCSLAVFPSIPLINTHSNLCLFSNFSHSCFLFCTHPDTLPTSLSINPKKLSLSFSFPLSQKRPFPNFLHPFTGSELSLFRCLLLFFFFLLFFLSFSFSFSFLFFLSQIFIVYFSSFPILHFLFFFFLCVCVFLSFLFSLSHLLSLAILFLPLLLRVFSTLSRLPRLFCLCLQKKRRVLIPFAFTSFRKIASLPCVC
Protein: Scribbler (Q9NHQ0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MESMRRNEANTSHHPNKVALNSSNVATESNIKNNKLLANLSAAGAATATTATTGTATTTTATTANQALNFNNKTKATANATAASANNRHNNNNNSSAIKKHTNTNKLAGKSPACNSSSSSLSSSSSSNSSESKDTNFEYEDEWNIGGIPELLDDLDADIEKSAHSSGGGNQATALNAKQANSSSTSSSSSSKGGASSSSSSAAATGSSSSHKSHKTTLHSNLSATSPTTIKFTRQPVAIGGANSSSSSSAAAAPSGGSANVVAKGSSSSSSSTSSSSSGKHHHHHHHHSNSSSSGSSSKGYKSALVAQLNSPSPLNSNSKSLSGSGSGSGNTNGAAGAGAGSTLSSSTFAGFSKGGSLVSSSAGAAAALAAGSGQQGSKFSAGGMSSQTGSGSGGNNTSNSNNSSSGSGGSGSGSSTGNTASGSGNNNSTSAGGPPSSQGGNNGNGSGSSSSSSSGKSSAKMSIDHQATLDKGLKMKIKRTKPGTKSSEAKHEIVKATDQQQNGALGAGSNNSANEDGSSGSSSTNASSLGSTNSSSSASSGSSSSSGSSSSSSKKHLNNASSGSGSSSSGGGSQNNASGHASGGGSSGSSQSTPQGTKRGSSGHRREKTKDKNAHSNRMSVDKSAAAASAAGEKDTPEKCSGTGAGGSPCSCNGDVGAPCSHHACIRRAAHMSNSAGNANSSAGTGQSGGSSSMSAVPPGVFTPSAGSPSTGSPSTVVPAAASLLAATGAASSSASQMASSSAGGVGGSGGGANAPGPPGKESAGSIKISSHIAAQLAAAAASNSYSGSGANTNQGQNSNAGGNGGSESKAAAAAQAKLMAPGMISATMHHTISVPAGTGTGDDDTKSPPAKRVKHEAGASGAGGGKEMVDICIGTSVGTITEPDCLGPCEPGTSVTLEGIVWHETEGGVLVVNVTWRGKTYVGTLLDCTRHDWAPPR
Protein: Invariant surface glycoprotein, putative (Q57VX8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSTMPVTLRTTATVFLLCGICALDVSKASNLPVAYKQYVTINGRKLDGEAVLTLCTMKKLLDGVADRADFLERQSWKYLKVAREIFQKVSEHDDMRAALGQKMLDQMRGVQRVANRTKRSVEEAWEKAKRAAANSSKVLKELLKWHCINKEAIRDSFDHMANANCDPSAYKHDYHRNFGHDDARAYVIYCEYKSIPAAKTDVTFSNMEGAVEAWNRAKPKADARDAVECSSGHSSRSASSSDKPCTLLESWRWDYDAARYAILKLETLVRNSLGVTHYAQRFQQIGRESLAQYLEWKKAAEARAAEEEAKRQAAEKAAEEARKALEEAEARRVAAEEQAEARRLEAEKAEKAKEAGQPVSEEKKKMLLEAVEEAEATEKAAEKQVKDSRKAFEEAEEERVKATEDAEVARWDKEGAEESEEKLKKDVEKLAEELKEESKESGEEDDVNADHDDEGSEAKSGWIGTTKVLIFLIPLLLLLLGLLVFFVIRGRRKAEVKDDINIEEANAKSKNTKTAAGFDSDI
Protein: BTB domain-containing protein (Q18776)
Organism: Caenorhabditis elegans
Interaction partners:
- Cullin-3
- Transmembrane protein 53
- Uncharacterized protein
- Trafficking protein particle complex subunit 11 domain-containing protein
- TUG ubiquitin-like domain-containing protein
- Homogentisate 1,2-dioxygenase
Sequence:
MDTRKVSVSNTTSPRQSSDTEMSSSCATSTASAIDESDVRFSFQDTIQAIRHMSSNTDDSTNQNGVAAVKTNGFHYGSSSSSWVRLNVGGKVFQTTRSTLMREPCSFLYRLCQDEMGLPTDRDETGAYLIDRDPDFFSPILNYLRHGKLIMNPGLSEEGILAEADFYNLPSLSQLIMDRIQDRENSVKDATNKFVYRVLQCHEEELASVVSAMTDGWKIVQVVPINSNYTNYTTEQPQEYLCIVERECPDNGSMLEGQDRAKLLQQRARHN
Protein: Beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Q4PNI0)
Organism: Uncultured marine bacterium 66A03
Function: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal. Exhibits the highest activity for beta-carotene, followed by beta-cryptoxanthin, beta-apo-4'-carotenal, alpha-carotene, and gamma-carotene in decreasing order, but has no activity on beta-apo-8'-carotenal, beta-apo-12'-carotenal, lutein, zeaxanthin, or lycopene, suggesting that the presence of one unsubstituted beta-ionone ring in a substrate with a molecular weight greater than C35 seems to be essential for enzyme activity.
Subcellular location: Cell membrane {ECO:0000255|HAMAP-Rule:MF_02093, ECO:0000305}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_02093, ECO:0000305}.
Interaction partners:
Sequence:
MGLMLIDWCALALVVFIGLPHGALDAAISFSMISSAKRIARLAGILLIYLLLATAFFLIWYQLPAFSLLIFLLISIIHFGMADFNASPSKLKWPHIIAHGGVVTVWLPLIQKNEVTKLFSILTNGPTPILWDILLIFFLCWSIGVCLHTYETLRSKHYNIAFELIGLIFLAWYAPPLVTFATYFCFIHSRRHFSFVWKQLQHMSSKKMMIGSAIILSCTSWLIGGGIYFFLNSKMIASEAALQTVFIGLAALTVPHMILIDFIFRPHSSRIKIKN
Protein: Os02g0178700 protein (cDNA clone:002-173-H03, full insert sequence) (Q6ETM0)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MRGPSTTTMATFKQSFLKNLLSSLKSSSKNKAAMSTLSERKRAIKSSADIAMATARTGIAGAARWPHAILASSSSSSSSSSSSSSSSSMPRTTFPCKMMQGKVRRRCKSIVRRRTPLMSSSSEVARRLVKKRDKVLRRMIPGGELIADEISLLHEAMDYVVHLHAQVDVLRRVSRAAVARRSSASSSSSGGLAQLKERTVQISGETENPC
Protein: Histone deacetylase 6 isoform C (Histone deacetylase 6, isoform C (EC 3.5.1.98)) (Q8IR37)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLTKDLNSFSQSPPIVTRRSAQQAKIQTRAMASKSKTGTTGAATAAGGTGSSSGSISGGFNAADPRKSNKPNAALLEAKRRARNNMLKNQGCGSQESVTDIFQNAVNSKSLVRKPTALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRHWIGGPPPMDRYPTRDTAIPLPPEKLTSNAARLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEPMAWTHGCAWREDGCYATGPDGRDEDDDDDNGAGSSICLRLERNN
Protein: Homeobox protein Hox-B6 (Homeobox protein Hox-2.2) (Homeobox protein MH-22A) (P09023)
Organism: Mus musculus (Mouse)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-B7
- Homeobox protein Hox-B5
- Homeobox protein Hox-B8
- Homeobox protein Hox-C4
- Homeobox protein Hox-B4
- Homeobox protein Hox-B3
- Pre-B-cell leukemia transcription factor 1
- Homeobox protein Hox-B9
- Homeobox protein Hox-B2
- Homeobox protein Hox-D4
Sequence:
MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFAASSYYPPAGGGYGRAAPCDYGPAPAFYREKDAACALSGADEPPPFHPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKPAE
Protein: EARP-interacting protein 1 (Endosome-associated recycling protein-interacting protein) (Q9U1Q0)
Organism: Caenorhabditis elegans
Function: Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the endosome-associated recycling protein (EARP) complex. Important for neuronal function.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:27191843}. Note=The cytoplasmic localization is supported by the over-expression of an eipr-1-GFP fusion protein.
Interaction partners:
- Vacuolar protein sorting-associated protein 51 homolog
- CARD domain-containing protein
- Vacuolar protein sorting-associated protein 54
- Vacuolar protein sorting-associated protein 53 homolog
- Vps54_N domain-containing protein
- Vacuolar protein sorting-associated protein 52 homolog
- Putative syntaxin 6
- NCA Localization Factor
- Carboxypeptidase D
Sequence:
MSECLMFGMDCEARCMTSMTADEENICFLVGTNNIKNDKNQVNKLFMDPEASRLMSKTFRHPAGEVRAIAAHPTKSTILATCTADFSSLGGTHSITIWNIEEDKRTLETVSRLPTEQVMSCLEWEPNSMKCAAMTPFRPEIQLLNMENGPEIVQNLKIPLENEEDEMFSATWSPHHDGNMLGVTGGRTAWCIDCRTDNEYLKIRDAHIHRTISMDFNPNLQHVIATCGDDGYVRIWDTRSTSSALTSLHPHAHWVWSVRFHPVHDQLLLTGGSDASVVLSCAQSVSSEQQIEFRDDEEEEEDDDLVEKLQDGQLERIDEHEDSVYACAWSSADPWTFASLSYDGRMIVSNVSRKHKYALMQL
Protein: Calpain 1, (Mu/I) large subunit a (EC 3.4.22.17) (Q7SYA9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MFSYGGISAHISANRLKADGAGSFEQALHFQNQDYEALRQECLEGGYLFEDPCFPAEPPSLGFKELAPHSSKTRDVEWMRPTELCDDPQFIVGGATRTDICQGALGDCWLLAAIGSLTLNERLLHRVVPHGQSFQDDYAGIFHFQFWQFGEWVDIVIDDRLPVKDGELMFVHSAEGNEFWSALVEKAYAKLNGSYEALSGGSTTEGFEDFTGGVSEMYELRKAPRDLYRIISKALDRGSLLGCSIDITSAFDMESVTFKKLVKGHAYSVTALKQVEYRGRMERLIRIRNPWGQVEWTGAWSDNSPEWDEIDPSEKDDLHLQMEDGEFWMSFGEFLRQFSRLEICNLTPDALSDDDMSHWNTIKFHGAWRRGSTAGGCRNHPNTFWINPQYKITLLEEDDDPEDEEVACSFLVALMQKDRRRYRGQGQDMHTIGFAIYEVPEEYTGCQNVHLKKDFFLSNSSAARSETFINLREVSTRLRLPPGEYIIVPSTFEPSKEADFVLRVFTEKQSETEELDDEISADLEDEEEITEDDIDDSFKSLFAQLAGEDMEISVHELKTILNRVVSKHKDVKTDGFSMDSCRTMVNLLDKDGSARLGLVEFQILWNKIRKLLGIFREFDIDKSGTMSSYEMRLAVESAGFKLNNRLNQILVARYAENEAIDFDNFVCCLIKLEAMFRSFQQLDREETGTAEMNLSEWLFMTMCG
Protein: dual-specificity kinase (EC 2.7.12.1) (A0A0A0MTH5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQLLPPPIRTGTKTQMDAKKPRKCDLTPFLVLKARKKQKFTSAKVGSKLSVQIQKPPSNIKNSRMTQVFHKNTSVTSLPFVDTKGKKNTVSFPHISKKVLLKSSLLYQENQAHNQMPASELKASEIPFHPSIKTQDPKAEEKSPKKQKVTLTAAEALKLFKNQLSPYEQSEILGYAELWFLGLEAKKLDTAPEKFSKTSFDDEHGFYLKVLHDHIAYRYEVLETIGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHQQALMELKILEALRKKDKDNTYNVVHMKDFFYFRNHFCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQKGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLPPAGFIQTASRRQTFFDSKGFPKNITNNRGKKRYPDSKDLTMVLKTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWIHQSRNLKPQPRPQTLRKSNSFFPSETRKDKVQGCHHSSRKDEITKETTEKTKDSPTKHVQHSGDQQDCLQHGADTVQLPQLVDAPKKSEAAVGAEVSMTSPGQSKNFSLKNTNVLPPIV
Protein: Penicillin-binding protein 2B (PBP-2B) (EC 3.4.16.4) (Penicillin-binding protein B) (Penicillin-sensitive peptidoglycan D,D-transpeptidase) (Q07868)
Organism: Bacillus subtilis (strain 168)
Function: Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins, thereby interrupting normal cell wall synthesis (Probable). This protein itself, but not its transpeptidase activity, is required for cell division.
Subcellular location: Cell membrane {ECO:0000269|PubMed:3080407, ECO:0000269|PubMed:8244929, ECO:0000305|PubMed:28792086}; Single-pass membrane protein {ECO:0000255}. Note=Localizes at mid cell, to cell division sites; localization requires FtsZ. {ECO:0000269|PubMed:28792086}.
Interaction partners:
- Cell division protein DivIB
- Probable peptidoglycan glycosyltransferase FtsW
- Cell division protein FtsL
- Cell division protein FtsZ
- Cell division protein FtsA
- Peptidoglycan glycosyltransferase RodA
- Septation ring formation regulator EzrA
- Cell division protein DivIC
- Stage V sporulation protein E
- Cell division protein SepF
Sequence:
MPKKNKFMNRGAAILSICFALFFFVILGRMAYIQITGKANGEVLATKATEQHEKKRTIEASRGSILDRKGKVIAEDTATYKLIAILDKKMTTDVKHPQHVVNKEKTAEALSKVINLDKADILDILNKDAKQVEFGSAGRDITYSQKQKIEKMKLPGISFLRDTKRYYPNGVFASNLIGYAEVDEETNEISGAMGLEKVLDKYLKERDGYVTYESDKSGWELPNSKNKITAPKNGDNVYLTIDQKIQTFLEDSMTKVAQKYNPKKIMAAVVDPKTGKVLAMGQRPSFDPNKRDVTNYYNDLISYAYEPGSTMKIFTLAAAMQENVFNANEKYKSGTFEVGGAPVKDHNNGVGWGPTTYHDGVLRSSNVAFAKLAKEKLGYDRLNQYLHKFNFYQKTGIDLPGEVSSKINFKYEFDKASTAYGQASAVTPIQQIQAATAIANDGKMMKPYVIDHIVDPDKDKTIYQNKPESAGTPISASTAKKVRDILGEVVTSKIGTGQAYKIEGFDVAGKTGTAQIAGKGGYLDGTDNYIFSFMGMAPKDDPELLIYVAVQQPQLKAGQSSSDPVSEIFNPTMKNSLHYLNIEPTEKSDSDKEETKAQTMPDLTDQTVAAAQKKAKEENLTPIVIGSDVAVKEQYPKADEEVLTNQKVFLKTGGKIKMPDMTGWSRREVLQYGELAGIHIEVSGQGYAVSQSVKKDKEIKDKTVIKVKFKNPD
Protein: AAA ATPase domain-containing protein (Q54EV3)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Luminal-binding protein 1
- GrpE protein homolog, mitochondrial
- Heat shock 70 kDa protein, mitochondrial
- Germination protein
Sequence:
MSFNPEEFTDKTNTILLRTQELAREKSNVQLAPIHLAVTLLNDEDNLAKSIFEKAGGDVPKIDAGFKRLLAKQPVQNPVPPEISPNSLFLQVLRSAARHQKNNGDSHLAVDHLILGLLDDRDILSVLGDAGATKEQVIQAVKEIRGNKKITSKTAESTYEALSKYGYDLVSQAQEGKLDPVIGRDEEIRRVIRVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVRGDIPDNLNARVIALDMGALIAGAKYRGDFEERLKAVLKEVKDSNGGIILFIDEIHLVLGAGKTDGAMDAANLLKPMLARGELRCIGATTLDEYRQYVEKDPAFERRFQQVFVNEPTVNDTISILRGLKERYETHHGVRITDNALVVAAQLSHRYITNRFLPDKAIDLVDEACANTRVQLNSQPEAIDNLERRRLQLEVESAALEKEEDDASKQRLKAVQEELNQIKDELQPLEAKYQKERSRVDKIRELRKKLEDIKVKLSDAERRYDTSAAADYRYFVIPDLEKQIEVCDKERKENKKDAMVSEVVTPEQIADVVSRWTGIPVSKLSQTEKQRLLSLADHLHNRVVGQDEAVDAVADAVLRSKSGLARENQPLGSFLFLGPTGVGKTELAKALALELFDDESHMVRIDMSEYMEQHSVSRLIGAPPGYVGYDQGGQLTEAVRRRPYSVVLFDEVEKAHQQVWNVLLQVLDEGRLTDGQGRTVDFSNVVIIMTSNLGSQYILGEQANKEGGNNSLSQACKDKVIDEVRKHFRPEFLNRLDDIIVFTPLSKENLHSIITLQLRSVEKRLEDQNMSLKISNDALDSIINAAYDPIFGGRPLKRYIEKNIVTELSKLILGGKLKENQGVVVNEKDHHLNFDIIDLKQQQQRPASPTKKQKTIK
Protein: 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) (EC 2.6.1.22) ((S)-3-amino-2-methylpropionate transaminase) (GABA aminotransferase) (Gamma-amino-N-butyrate transaminase) (L-AIBAT) (H3BRN4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MWWQHAKGVPVPQGVMASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK
Protein: Actin-interacting protein 1 (Q582R9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cofilin/actin depolymerizing factor, putative
- Actin-like protein 3, putative
- Cilia- and flagella-associated protein 45
Sequence:
MSVHQLQLEGIIPSAPSTTRATPTSISAHDTLVAYGSGNNVVVRDISTTGADSILCCWHHTSPVTAVRISPSSKFVASGDQKGNVRLWERRNGTQEKYNGQLLEGPVRDVAWTRDEERLVVVGDGRNNFAAAVTVSGNTIGSINGHTQSILSCDVRGDRPFRAVTGSADNMVGFYEGVPFKFTCNVKEHNEKVMCVRYSPDMETIATVARTGNIILLDGRTGDKKGSISVDHKGSIFSLAWSPDGKLIATASADKTVKVFDVTSASNIATCSTGNRVLDMQQGVAYTARGVVSVSFGGKLTLINEKGEMTRTFLGHQGRIFLLHKESDELMVSVSVDRALIWRDTAAAAAGEASEVPLSADLITAAAFSGGKLYIVAGSELLRYDPNDSTPAVVSQDVTAVTALTVTEDGTAVLLLRNSFIVINSAGSKIAEEKLDRFDGCSAAARGQMIIVGGEKLVKGYQITESAPPEAKVQFAGHHTGAVACLAFSHDGQVVASGDANRNIFVWSWADGSVLHKDLVFHTLRVTSLSFAYNSNTRLFSGSMDASLILWDLEAKTRRMEDAAHRGGVSAVFGAADGTLISGGSDGCIRLWKSNN
Protein: T-cell surface glycoprotein CD3 epsilon chain (P70069)
Organism: Gallus gallus (Chicken)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MRCEVPLPLLGLLLCVVGAAAQGGQEEFAVEISGTTVTITCPSSGDDIKWKPDPALGDNNKYIIQNHDSSPLTVSCTAGDQEHTMYLNAKVCANCEELDTFTVVGIIAADLLITLGVLILVYYFSKNKKGQSRAAAGSRPRAQKMQRPPPVPNPDYEPIRKGQRDVYAGLEHRGF
Protein: DNA-binding protein (Zinc knuckle (CCHC-type) family protein) (Q8GXC5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DNA-directed RNA polymerase II subunit 4
- DNA-directed RNA polymerases II, IV and V subunit 11
- Transcription initiation factor IIF subunit alpha
- FACT complex subunit SSRP1
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Pentatricopeptide repeat-containing protein At4g30825
- General transcription and DNA repair factor IIH subunit TFB4
- Transcription initiation factor IIA subunit 2
- General transcription and DNA repair factor IIH subunit TFB2
- General transcription factor IIH subunit 2
Sequence:
MSSMSRSRSRSRSRSRDRFRSRSPRDRRMRSERVSYHDAPSRREREPRRAFSQGNLCNNCKRPGHFARDCSNVSVCNNCGLPGHIAAECTAESRCWNCREPGHVASNCSNEGICHSCGKSGHRARDCSNSDSRAGDLRLCNNCFKQGHLAADCTNDKACKNCRTSGHIARDCRNDPVCNICSISGHVARHCPKGDSNYSDRGSRVRDGGMQRGGLSRMSRDREGVSAMIICHNCGGRGHRAYECPSARVADRGFRRY
Protein: Protein FAM186B (Q8IYM0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEKDDPPQLVTPTSVKAIILRIEAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDLKENAKSQQRDPKGKKRFILLEKIASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKSEEEAAALDEWIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISPANIKKKVYHMDMEAQRKNLQLLSEESELRLPHYLRSKALELTTTTMELGALRLQYLCHKYIFYRRLQSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGLEEKHRECLSSMVTMFPKLQLEWNVHLNIPEVTSPKPKKCKLPAASPRHIRPSGPTYKQPFLSRHRACVPLQMARQQGKQMEAVWKTEVASSSYAIEKKTPASLPRDQLRGHPDIPRLLTLDV