wanglab/gogpt-training-data huggingface dataset:
Protein: Cytochrome P450 1A5 (EC 1.14.14.1) (CYPIA5) (Cytochrome P450 TCDDAA) (P79761)
Organism: Gallus gallus (Chicken)
Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Interaction partners:
- UDP-glucuronosyltransferase
- Cholesterol 7-alpha-monooxygenase
- Uncharacterized protein.
- Epoxide hydrolase
- Epoxide hydrolase 1
- Uncharacterized protein
- UDP-glucuronosyltransferase
- Cytochrome P450 1A4
- 11-beta-hydroxysteroid dehydrogenase 1
- Aromatase
Sequence:
MGPEEVMVQASSPGLISATEVLVAAATFCLLLLLTQTRRQHAPKGLRSPPGPRGLPMLGSVLELRKDPHLVLTRLSRKYGDVMEVTIGSRPVVVLSGLETIKQALVRQAEDFMGRPDLYSFRHITDGQSLTFSTDTGEMWKARRKLAQNALKNFSIAASPTASSSCLLEEHVSTEASYLVTKFLQLMEEKQSFDPYRYMVVSVANVICAICFGKRYDHDDQELLSVVNVVDEFVDVTAAGNPADFIPLLRYLPSRNMDSFLDFNKRFMKLLQTAVEEHYQTFDKNNIRDVTDSLIEQCVEKKAEANGATQIPNEKIINLVNDIFGAGFDTVTTALSWSLMYLVTYPHMQKKIQAELDQTIGRERRPRLSDRGMLPYTEAFILEMFRHSSFMPFTIPHSTTRDTVLNGYYIPKDRCVFINQWQVNHDEKLWKDPQAFNPERFLNAEGTEVNKVDAEKVMTFGLGKRRCIGENIGKWEVFLFLSTLLQQLEFSIQDGKKADMTPIYGLSMKHKRCEHFQVKKRFSMKSSN
Protein: Scavenger receptor (Q58SM0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
TCDRDGRLRGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGAYGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGTNGFSTTTEPTAPTGSNEQPLVYDMMSCSGRCGTSISASNITNNGIVMGCGCNDECLSDETCCLNYLEECTKELLTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTTTSTTTTKRPTTTTTTTKATTTKRTTTTKKPTTTSTTPKPTTTTSTTPKSTTSTTSTTSTTPTTTTTINVFTTKKTTIMIPTSSTEKTTGINTTMKTRKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLGIVLVVVLANVVNRWIIPITGSKTSSEKAVRFKKAFDSLKKQRKRNSMDDQPLCDSDNDDVEYFEEMGVDIRHRTDL
Protein: Heat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (P15991)
Organism: Cricetulus longicaudatus (Long-tailed dwarf hamster)
Function: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P04792}. Nucleus {ECO:0000250|UniProtKB:P04792}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P04792}. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. {ECO:0000250|UniProtKB:P04792}.
Interaction partners:
Sequence:
MTERRVPFSLLRSPSWEPFRDWYPAHSRLFDQAFGVPRLPDEWSQWFSAAGWPGYVRPLPAATAEGPAAVALAAPLAAPAFHRALNRQLSSGVSEIRQTADRWRVSLDVNHFAPEELTVKTKEGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKTATQSAEITIPVTFEARAQIGGQEAGKSEQSGAK
Protein: Neuronal pentraxin 2b (Neuronal pentraxin-2b precursor) (D2D0C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MLHLIAGLICVYGLTCVKIVYGQTEKGERFLCTAVPIDQDTSCPVPVPSASLQEEELRNTVMQLRETILQQKETIVNQLGTIKELTSKLSRCESESEIFRKMNKDTMDDXPKDPNDTIDVLGKTMQGLKDRLENLEQQQMRANASGASFPNELRNLLQHRLEDLENQLLKKVNELEEEKSQLYNETVAHRQRTDNTLNSLMNRISELEKGGAGFKSPENFKISLPLRTNYLFGQVKKSLPEMYAFTICMWLKSGSSPGIGTPFSYGVPGQANEIVLIEWGHNPIELLINDKVAQLPLSLSDGRWHHVCITWTTRDGLWEAYQDGQRLGSGENLAPWHPIKPGGVLILGQEQDVVGGRFDATQAFVGELSHFNIWDRVLRSTDIITMANCSSYMPGNVVSWTDSNIEVFGGASXGPLELCEDRLFDN
Protein: At5g38890 (Nucleic acid-binding, OB-fold-like protein) (A2RVT9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- Exosome complex component RRP41 homolog
- Exosome complex component RRP4 homolog
- Ribosomal RNA-processing protein 43
- Ribosomal RNA-processing protein 42
- Ribosomal RNA-processing protein 40
- Nuclear nucleic acid-binding protein C1D
- Exosome complex exonuclease RRP46 homolog
- Ribosomal RNA-processing protein 40
- Exosome complex component RRP45A
- Exosome complex component RRP45B
Sequence:
MTTGLVTPGDVIGKATEFKAGKGAYVNDATIYASLTGTCRIVSPLPESIDQRAIVEVTGHKAHGPIPETGSVVIARVTKVMTKMAAVDILCVGSKAVRENFAGVIRQQDVRATEIDKVDMHQSFHAGDIVRAMVLSLGDARAYYLSTAKNELGVVSAESAAGETMVPISWTEMQCPLSGQTEQRKVAKVGN
Protein: B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (R-RCD1) (RCD) (Q9QYN5)
Organism: Rattus norvegicus (Rat)
Function: Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Recruited by activated CARD domain-containing proteins: homooligomerized CARD domain-containing proteins form a nucleating helical template that recruits BCL10 via CARD-CARD interaction, thereby promoting polymerization of BCL10, subsequent recruitment of MALT1 and formation of a CBM complex. This leads to activation of NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Activated by CARD9 downstream of C-type lectin receptors; CARD9-mediated signals are essential for antifungal immunity. Activated by CARD11 downstream of T-cell receptor (TCR) and B-cell receptor (BCR). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O95999}. Membrane raft {ECO:0000250|UniProtKB:O95999}. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts. {ECO:0000250|UniProtKB:O95999}.
Interaction partners:
- Paracaspase
- Caspase recruitment domain-containing protein 9
- NF-kappa-B essential modulator
- Caspase-8
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- TNF receptor-associated factor 6
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase kinase kinase 7
- Caspase recruitment domain-containing protein 10
Sequence:
MEAPAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFAAGATNNLSRSNSDESNFSEKQRPSTVIYHPEGESSTAPFFSTESSLNLPVLEVGRLENSSFSSASLPRPGDPGAPPLPPDLRLEEGGSCGNSSEMFLPLRSRALSRQ
Protein: Large ribosomal subunit protein uL10 (50S ribosomal protein L10) (O51352)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Interaction partners:
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein bL28
- Large ribosomal subunit protein bL35
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS9
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS13
Sequence:
MSAKINAKKLEMFDLLKQFIDSKQNLFFLDYRGLNVAQLTELRNKIEGEHGSLKVVKNNIMKMVLKEKNINVVDSCLVGPTVVVTALEEANVIAKIFYDFVKSSTLKVKGGFVLGEFYDEAKVQAYSKLPTKKESISLFASVLKAPVSKLARTLKALADVKN
Protein: THO complex subunit 4D (ALYREF homolog 4) (AtALY4) (Q6NQ72)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Export adapter involved in nuclear export of spliced and unspliced mRNA. Plays a role in disease resistance. Mediates multiple defense responses triggered by NEP1, including stomatal closure, hypersensitive cell death (HCD) and defense-related gene expression.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:11432957, ECO:0000269|PubMed:15299117}. Nucleus, nucleolus {ECO:0000269|PubMed:15299117}.
Interaction partners:
- THO complex subunit 4B
- Protein mago nashi homolog
- RNA-binding protein Y14
- THO complex subunit 2
- DEAD-box ATP-dependent RNA helicase 15
- THO complex subunit 3
- THO complex subunit 5B
- THO complex subunit 5A
- THO complex subunit 1
- Histone deacetylase complex subunit SAP18
Sequence:
MSGALNMTLDEIVKRGKTARSGGRGISRGRGRGRGGGGRGAGPARRGPLAVNARPSSFTINKPVRRVRSLPWQSGLFEDGLRAAGASGVEVGTRLHVTNLDQGVTNEDIRELFSEIGEVERYAIHYDKNGRPSGTAEVVYPRRSDAFQALKKYNNVLLDGRPMRLEILGGNNSSEAPLSGRVNVNVTGLNGRLKRTVVIQQGGGGRGRVRGGRGGRGPAPTVSRRLPIHNQQGGGMRGGRGGFRARGRGNGGRGRGGGRGNGKKPVEKSAADLDKDLESYHADAMNTS
Protein: Fork head domain protein FKD3 (Forkhead box B1.2) (Forkhead box B1a) (Forkhead box protein B1a) (Foxb1.2 protein) (O73779)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
Sequence:
MPRPGRNTYSDQKPPYSYISLTAMAIQSCPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVMTSEHLAPSKPSDAAHYLQQHAKLRLSALGTHLPQMSSYNLGVSQPSTFKHPFAIENIIAREYKVPGGLAFSTGYPLHNQLTTAWPHMYSTSMMDSAAPISMTSSDYSAYGVPIKSLCHGGQTLPAIPVPIKPTPAALPHHIPAFLSNSPQSLSPTSPQTATSQSSPATPSETLTGPATLQSVAVH
Protein: Auracyanin-B (Ac-B) [Cleaved into: Auracyanin-B-1; Auracyanin-B-2] (P27197)
Organism: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Function: Probably a soluble electron acceptor for the integral membrane protein electron transfer alternative complex III (ACIII).
Subcellular location: Cell membrane {ECO:0000305|PubMed:1313011}; Peripheral membrane protein {ECO:0000305|PubMed:1313011}. Note=Possibly located on the extracellular face of the cell membrane.
Interaction partners:
Sequence:
MSWRGSGRSNFRSRSSSNGGSTFSGGSAGGPPLIVMMGLAFGAGLIMLIVMIASNATAGGFVAATPRPTATPRPTAAPAPTQPPAAQPTTAPATQAANAPGGSNVVNETPAQTVEVRAAPDALAFAQTSLSLPANTVVRLDFVNQNNLGVQHNWVLVNGGDDVAAAVNTAAQNNADALFVPPPDTPNALAWTAMLNAGESGSVTFRTPAPGTYLYICTFPGHYLAGMKGTLTVTP
Protein: Chordin-like protein 2 (Q8VEA6)
Organism: Mus musculus (Mouse)
Function: Implicated in tumor angiogenesis (By similarity). May inhibits BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. May play a role during myoblast and osteoblast differentiation, and maturation.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MVPGVRIIPSLLGLVMFWLPLDSQARSRSGKVCLFGEKIYTPGQSWHPYLEPQGTIYCVRCTCSENGHVNCYRLRCPPLHCSQPVMEPQQCCPRCVDPHVPSGLRVPLKSCQLNETTYQHGEIFSAQELFPARLSNQCVLCSCIEGHTYCGLMTCPEPSCPTTLPLPDSCCQTCKDRTTESSTEENLTQLQHGERHSQDPCSERRGPSTPAPTSLSSPLGFIPRHFQSVGMGSTTIKIILKEKHKKACTHNGKTYSHGEVWHPTVLSFGPMPCILCTCIDGYQDCHRVTCPTQYPCSQPKKVAGKCCKICPEDEAEDDHSEVISTRCPKVPGQFHVYTLASPSPDSLHRFVLEHEASDQVEMYIWKLVKGIYHLVQIKRVRKQDFQKEAQNFRLLTGTHEGYWTVFLAQTPELKVTASPDKVTKTL
Protein: Calcium/calmodulin-dependent protein kinase I (EC 2.7.11.17) (P27466)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Important in cellular regulation.
Interaction partners:
- Calmodulin
- Calcineurin subunit B
- Serine/threonine-protein phosphatase 2B catalytic subunit A1
- Serine/threonine-protein phosphatase 2B catalytic subunit A2
- Cell cycle protein kinase DBF2
Sequence:
MDDKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIICTELKTHNLLPGLKEGLDARQKFRNSVERVRLNMKIQKLRDLYLEQTESDSDFDEGSQANGSVPPLKATDTSQLSKKLSEEEQSKLKSELTSKAFAQLVNTVLAEKEKFLNINRVCSSDSDLPGSDIKSLDEAKEKPEGKDTKTEE
Protein: Eukaryotic translation initiation factor 4C (Q9NJB4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPKNKGKGGKNRRRGKNENEFEKRELIFKEDQQEYAQVTKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINQGEIILVGLRDYQDSKADVILKYTPDEARNLKTYGEFPESVRINETVTFVEDGFDEDIEFGDEISSEDDADSVDNI
Protein: Protein-tyrosine-phosphatase (Q93592)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTLSFRVNPEYAAMSEIVPGLFICGVSALSKDEMKKHKITHIINATTEVPNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNVKENAGSVRLVRDEAQPEQLLPDVYLNIAIPARPASPEQDPNMIPDEPRERRNSGFKSKFRPVLEPVMEMAEAVC
Protein: EWS RNA-binding protein 1 (A0A8I6A3F5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQSTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPAETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSSQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSLSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGLQSESLVYTSILKKYPYSVLSRQHNEKWD
Protein: Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member) (Q68DB7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU361195}. Nucleus {ECO:0000256|RuleBase:RU361195}.
Interaction partners:
Sequence:
MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
Protein: Gamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1) (GABAAR subunit gamma-1) (Q9R0Y8)
Organism: Mus musculus (Mouse)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular location: Postsynaptic cell membrane; Multi-pass membrane protein {ECO:0000255}. Cell membrane; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit beta-1
- Inactive phospholipase C-like protein 1
- Vesicle-fusing ATPase
- Huntingtin-associated protein 1
- Gamma-aminobutyric acid receptor subunit alpha-1
- Trafficking protein, kinesin binding 2
- Gamma-aminobutyric acid receptor-associated protein
- Gamma-aminobutyric acid receptor subunit alpha-2
- Gamma-aminobutyric acid receptor subunit alpha-4
- Gamma-aminobutyric acid receptor subunit beta-3
Sequence:
MGSGKAFLFSPSLLWSQTRGVRLIFLLLTLHLGNCVDKADDEDDEDLTMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRGRKLKNKTSASPGLHAGSTLIPMNSISLPQGEDDYGYQCLEGKDCTSFFCCFDDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL
Protein: Mediator-associated protein 2 (F4KF27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 6
- DNA binding / DNA-directed RNA polymerase
- Small RNA degrading nuclease 3
- GLABROUS1 enhancer-binding protein-like
- Mediator of RNA polymerase II transcription subunit 19a
- Mediator-associated protein 3
- rRNA 2'-O-methyltransferase fibrillarin 2
- Mediator of RNA polymerase II transcription subunit 22a
- Mediator of RNA polymerase II transcription subunit 9
- Mediator of RNA polymerase II transcription subunit 23
Sequence:
MDFDFKVSGDFIVSGAEQLDDTDLTRSDEFWLIQAPLGQFPEIEENTLKIEPDKDGLFGEFKDSNAGSLHLCLGAKYDLASFHSQDAGAELIIPSEESMIVGKITRRVALVRYPEPNELLQKMKARTQQKLVGSVTNSSKKSSNLTQSSRHKSGTRSSREKSMFSGFTETPKSPKRKNSESSSGKHRSSTSTVSGSSERSAKSKKKVKKEE
Protein: ERCC excision repair 6, chromatin remodeling factor (D3ZS47)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MPHEEIPNSTQPQGQDWLPGQHVSADRDIPAGQETAGDSEAGKCLSSPSCDHGPSTSAEACVLAATRWGPALLHIDRHQIPAVEPSAQALELQGLGVDVYDQAVLEEGVLQQVDSAMHEASRVAQRADAEKEYQSVLDDLMSCTTSLRQINKIIEQLSPQAASNRDINRKLDSVKRQKYNKEQQLKKITAKQKRLQAILGGAEVHVELDHGSLEEEDAEPGPSCLGSMLMPAQESAWEELIRTGQMTPFGTPAPQKQEKKPRKIMLNEASGFEKYLADQAQLSFKRKKQAANKRTAKKAVVVSESSRGPNETKPNQRSQALSQTDKRLKKHIRKLQRRALQFQGKVGLQRGKRPLEPEERPGAEGDTEAVLSSDDISYELKPLRKGQKYEKKVPVQEIDDDFFPSSEEEDEAVEGRGGGRKVSRRPDDGDEDYYKQRLRRWNRLRLQDKEKLKLEDDSEESDAEFDEGFKVPGFLFKKLFKFEGLGPTLIVCPTTVMHQWVKEFHTWWPPFRVAILHETGSCAHRKERLVRDIVHCHGVLITSYSYIRLMQDDISRHDWHYVILDEGHKIRNPNAAVTLACKQNNLRELWSLFDFTFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFIDSKAVYRILNGENQIFSGLVALRKICNHPDLFSGGPKNTSALPEDGLEEEQFGYWKRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLHILEVFLRAHKYSYLKMDGTTTIASRQPLITKYNEDTSIFVFLLTTRVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLTSPDASQGTETSAIFAGTGSNIQTLKCHFKKRTPPVLQMDPKRKKPLVSDTSVNGATVMEEKSQGSGATGSVPSTESGPLKSDRHTDGSRASSVGFGEEADAGSTLEHLSGLSGDSPAVDHTSRLSAVASTSEKQGSSYEGECCQAQTGPVHLSEQTEGHFSKHKSKRKHDAAEEETTEKCPQPKQKAKNSRHHRDAKFEGTRVPHLVKKRRYHQQTTEQESGAKDRSSDDYVLEKLFKKSVGVHSVVKHDAIIDGSSPDYVLVEAEANRVAQDALKALRLSRQQCLGATSGVPTWTGHRGISGAPAGVKMRARNHMILPERLESDGEQLAGAAAAAAPPCSTEHDALLVDMRNFIAFQAQVDGQASTQEILQAFESKLSVAQSCVFRELLRNLCNFHRTPGGEGIWKLKPEYC
Protein: Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase) (Q02787)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03125}.
Interaction partners:
- Adenylosuccinate lyase
- Inosine-5'-monophosphate dehydrogenase
- Bifunctional purine biosynthesis protein ade10
- Argininosuccinate synthase
- Inosine triphosphate pyrophosphatase
- Dihydroorotate dehydrogenase
- AMP deaminase
- Multifunctional tryptophan biosynthesis protein
- Multifunctional protein ura1
- Probable asparagine synthetase
Sequence:
MASVRETGVNVSNDGITVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELEKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRKNVADLQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKFVGVPITFIGVGPGRDEMLVKE
Protein: Putative aldehyde dehydrogenase family 7 member A1 homolog (EC 1.2.1.3) (Antiquitin-1) (P83401)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Alcohol dehydrogenase class-3
- medium-chain acyl-CoA ligase
- medium-chain acyl-CoA ligase
- Acetyl-coenzyme A synthetase
- 4-aminobutyrate aminotransferase
- Beta-ureidopropionase
- Aldose reductase C
- Aldose reductase B
- Aldose reductase A
- Aminoadipic semialdehyde synthase
Sequence:
MTTFNEYPFLAELGIKAENNDGVFNGKWGGAGEIIKCLNPTNNKVIATVRGAAPEEYETCIQAMLAAKVKWALTPAPRRGEIVRLIGQAMREKIEPLSKLISLEMGKIYIEAKGEVQEFIDVCDYATGLSRSINGQVMPSERPNHILMETWNPLGLVGIITAFNFPCAVLGWNAAISMICGNVQLWKGASTTSLITLAVSKIIEKVLVENDVDPAVCCVLIGPGRTVGEQMIQDKRFGLISFTGSTEVGRRISSTVHGYFGKTILELGGNNAIVVAEDADIELVLRAVLFASVGTTGQRCTTCRRLFVHESLYDTILERLTKAYKTIKIGNPLEEGVLVGPLHTQSAVKEFTEGLEEIKKQGGKVVIGGNKLDISGGNFVEPTVVAIEHDAPIVKTELFVPILYIMKFKNLDDAFAWNNEVPQGLSSSLFTNNQKNIFKWLGPTGSDCGIVNVNVATNGAEIGGAFGGEKETGGGRESGSDSWKQYCRRSTNTINYGNTMPLSQGINFN
Protein: CHK kinase-like domain-containing protein (Q9VBS4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GH11066p
- RH40246p
- RH61816p
- GEO09657p1
Sequence:
MHPQTKDEDVSQKQVTIPDWVKPTVFEELLKRIVKDYKATKSMRANAGVAAGENYATVMLRIELDVEKEDNTQTTKAFMLKTPHQSEQYRKVIEKTDIFDVERGMYVEVVPELEQLYRDVGLEVKFGAELYDIEASDYYVLLEDLRPRGFGNIDRLEGMDQAHTECVLKKFAQWHAASAVRVETKGPYQEKYTKGFLRNEEIVDAFINRSIKVFLDNVHLCKGYETYLNDLRIVSGKTFEIVESLNNPSPDEFIALNHGDGWANNIMSQYNTKGEIQDTYFVDLQVPKWGSVTQDLYYFLLSSTSLDIKTSKFDYFIWFYHSELVKHLKLLGYSKTLPTLRRINDALNKYSGWSFICTATILAYVLLDPVDGADFDKVLGDDDCSFKNSLYINPRFRKHMEVLLPWLQHRGAME
Protein: UNC-13 (Q9U4K9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MILTNEMVNIGMLDSESEFGLIENSYSYQVPDNEQIDSVNSYNNKTQNVTNNGIEKANTKNKPVPLHDPPTKKASTVGMFGSILGKAAAAVQSATQAVNQSASSVASVVAQKPTIVPRTNNVLLLASVCSPNEIKRNSSSVEFDSEYGYQMPDVESLSSHYANTGGDYDNSNMKIHEFGTYARYRPYADYHTNGNQSQFKEEAVIPGEPEVINTNILPIGPQATGKKLPTVNGKSALLIKQMPTEVYDDESDTDELDVSPSTGKVPSYSIYSVQEDYYMDLQQTTPSIQPNGFYEQVNNGYDYREDYFNEEDEYKYLEQQREQEEHNQPKNKKYLKQAKISKIQPPSLDFIDVGQDDDFIYDNYHSEDDSGNYLEGSSSGSVGPIEGSIIKVDSNIEASFASLNKKSDSFTPTNDSLQKHDTVIGESTTKLTRLRTEKMCPDVDEEDENLSDHVSDLTDLSKLISQKKKTLLRGETEEVVGGHMQVLRQTEITARQRWHWAYNKIIMQLNNGGGPGEVGLRTNGHPGDNPFYSNIDSMPDIRPRRKSIPLVSELTMAATKRNAGLTSCLFHVQRLNDEDLKMHVYKKALQALIYPISSTTPHNFLLWTATSPTYCYECEGLLWGIARQGVRCTECGVKCHEKCKDLLNADCLQRAAEKSSKHGAEDKANSIITAMKDRMKQREREKPEIFELIRMTFGVDPDTHIDSLEQAEHAPVEGTSKWSCKLTITVICAQGLIAKDKSGTSDPYVTVQVSKVKKRTRTMPQELNPVWNEKFHFECHNSSDRIKVRVWDEDNDLKSKLRQKLTRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHYLCEENTGMVKLPTQKGDDAWKLYFDEIPEEIVDEYSMRYGIENNYQAMTHFHCLSAKYMCPGVPAVMSTLLANINAYYAHTTASSAVSASDRFAASNFGKEKFVKLLDQLHNSLRIDLSMYRNNFPASSPEKLMDLKSTVDLLTSITFFRMKVQELSSPPRASTVVKDCVKACLRSTYQFLFENCYELYNREFQVDPNEAKRAPDDHEPKLDSADFWHKLIALIVSVIDEDKNSYGTGLNQFPQELNIGQLSASSMGHLFAVDMKYALREEHEAHRLCKSAAYMNLHFRVKWLYSNYVKEVPPYKGAVPDYPAWFEPFVMQWLNENDDVSLEYLHGAFKRDKKDGFQKSSEHALFSNSVVDVFTQLTQCFDVVSKLECPDPEIWKRYMRRFAKTIVKVLIAYADIGKLEFPEHMKDERIACILMNNIQQLRVQLEKMFESMGGGELEEDAAHILKELQQNLTFALDDLTSQFRYQFGAPNNFIQCENFGNMLLFIKRRQWNPCCGNLAAQRNAVAVEADEVLRPLMDLLDGSLTLYAQSCEKTVLKRLLKELWKIVMRILEKTIVLPPMTDKTMMFKHLTDNAKNLASNAKIEDMGRLFKSHMAGKQDVKSALSGVMDISKEVEKNLSPKQCAVLDVALDTIKQYFHAGGNGLKKTFLEKSPELQMLRYALSLYTQMTDTLIKTFISSQVHEVDLENSEESVGEISVQIDLFSHPGTGEHKVNVKVVAANDLKWQIPSGMFRPFVDINLIGPHLQEKKRKFATKSKSNNWSPKYNESFSFTIGNEEQLDFFELHICVKDYCFARDDRLVGVAVIPLKDISEKGSVACWLPLMRRIEMDETGWTILRILSQRNNDEVAKEFVKLKSEIRQEPTMGT
Protein: Proteasome subunit alpha type (Q9VK14)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU000551}. Nucleus {ECO:0000256|RuleBase:RU000551}.
Interaction partners:
- Proteasome subunit alpha type-2
- Proteasome subunit beta type-1
- Proteasome subunit alpha type-3
- Proteasome subunit alpha type-5
- Proteasome subunit beta type-3
- 26S proteasome non-ATPase regulatory subunit 14
- Proteasome subunit beta type-4
- Proteasome subunit beta
- Proteasome subunit beta
- 26S proteasome non-ATPase regulatory subunit 4
Sequence:
MFRNQYDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTSKDTNTLQRKIMPVDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGVGLLVAGYDEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAIRGSLGSDDVENLTINVAIVGKDVPFKMFTEAENQKYVKLVKAMDPPLEADHDPLSEEGMSDDDMTDHGPSSSGVPPNDTSDMETTASTGGSDAH