wanglab/gogpt-training-data huggingface dataset:
Protein: Probable ribose-5-phosphate isomerase 4, chloroplastic (EC 5.3.1.6) (Phosphoriboisomerase 4) (Q9FI13)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Ribulose-5-phosphate-3-epimerase, chloroplastic
- Ribulose-phosphate 3-epimerase
- Ribulose-phosphate 3-epimerase
- 6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic
- 6-phosphogluconate dehydrogenase, decarboxylating 2
- 6-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic
- Transketolase-2, chloroplastic
- Transketolase-1, chloroplastic
- Phosphoribulokinase, chloroplastic
- Ribose-phosphate pyrophosphokinase 1, chloroplastic
Sequence:
MVTATASTPFSLSSSVVFTRRRNFKRFPVCASLSPEVSPLLRAAHHTVDNYVKSGMIIGLGSGEASDFAIRYLGQQLGSGSLHNVVGVPMSARSASEAAKYGIPLEYYRDGVQIDFAFHDADAVEENTLIAVIGRRRSSQEDDYILKQKSIVKVADEAVFMIKEEQYKAGLEGSIPVLVQSLNWLAIAEEIDDLYLGDAEVWRRASVENEGPLGGDFPIVTSDGHNILDVIFTTPIRSLADLATSLDKIDGVVDHGLIIKTRCTVVIAEETVVRSVTLQTSALEGGVRTYGQTLQK
Protein: Protein FAM8A1 (Autosomal highly conserved protein) (Q9UBU6)
Organism: Homo sapiens (Human)
Function: Plays a role in the assembly of the HRD1 complex, a complex involved in the ubiquitin-proteasome-dependent process of ER-associated degradation (ERAD).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein OS-9
- E3 ubiquitin-protein ligase synoviolin
- Protein sel-1 homolog 1
- Endoplasmic reticulum lectin 1
- Ubiquitin carboxyl-terminal hydrolase 33
- Lipid droplet-regulating VLDL assembly factor AUP1
- Ubiquitin-like-conjugating enzyme ATG3
- Derlin-2
- Derlin-1
Sequence:
MAEGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQAGREYVIPSLAHRFMAEMVDFFILFFIKATIVLSIMHLSGIKDISKFAMHYIIEEIDEDTSMEDLQKMMVVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSSNVSITTSTIRALIKNFSIASFFPAFITLLFFQHNRTAYDIVAGTIVVKRNGVR
Protein: Activatory protein CHA4 (P43634)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Activates the CHA1 gene for L-serine dehydratase. Binds to the DNA sequence 5'-GVGGARAYRTRATTCCRC-3'.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Catabolic L-serine/threonine dehydratase
- D-3-phosphoglycerate dehydrogenase 1
Sequence:
MMLEPSPPPLTTTVTPSLPSSLKKSVTDNDQNNNNVPRKRKLACQNCRRRRRKCNMEKPCSNCIKFRTECVFTQQDLRNKRYSTTYVEALQSQIRSLKEQLQILSSSSSTIASNALSSLKNNSDHGDAPNEKILKYGETAQSALPSSESNDENESDAFTKKMPSESPPPVGTNSIYPSNSLSIIKKKTDGSTRYQQQQVSLKNLSRSPLILRSLSLFFKWLYPGHYLFIHRETFLSAFFGDTNTKSYYCSEELVFAIAALGSLISYKSETELFQQSEVFYQRAKTIVLKKIFQLEDSSLAESSSSSKLAIIQTLLCLAFYDIGSGENPMAWYLSGLAFRIAHEIGLHLNPEAWSNVYEDELSIMDFEVRSRIYWGCYIADHLIAILFGRSTSLRLSNSTVPETDELPEIETGIEEYIYDPKVILSTANPLKKLIVLSRITEIFASKIFSPNETLLQRSEYLAKFNLEVYNWRRDLPPELQWTKRSLMEMTDFNPTIAYVWFHYYIVLISYNKPFIYEIKQSRELVEGYVDELYYLLKVWKNKFKTFEKATIYMIYSAILAIQCMKSNLIKKDRKQDFLNFLSAPTLNYELARKFIENSEDALHNSETMDLLGTLSHGNDFALEYNFDFTLLNEIDMLIGGNTNDGLSK
Protein: Protein WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT 1 (Protein WEB1) (O48724)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photorelocation movement via cp-actin filaments regulation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20974974}.
Interaction partners:
- Uncharacterized protein At1g66480
- J domain-containing protein required for chloroplast accumulation response 1
- Protein PLASTID MOVEMENT IMPAIRED 2
- Protein PLASTID MOVEMENT IMPAIRED 15
- Protein CHUP1, chloroplastic
- Protein PLASTID MOVEMENT IMPAIRED 1
- Protein PLASTID MOVEMENT IMPAIRED 1-RELATED 1
- At1g21660
- Protein PLASTID MOVEMENT IMPAIRED 1-RELATED 2
- Kinesin-like protein KIN-14A
Sequence:
MEDLKTVEASDNVVSDNVEKVNPELIDSTIRESNIQSATKVDNIPQSQTDTEETQQSQTDTEETQQSQTDDTTGNAKIYVDDTFSPSDAATAAVLTGKDSTSTTIVEEVMEPDEIGLPSVKITEAATGTARNGGGSPRTVSSPRFSGSPVSTGTPKNVDSHRGLIDTAAPFESVKEAVSKFGGITDWKSHRMQAVERRKLIEEELKKIHEEIPEYKTHSETAEAAKLQVLKELESTKRLIEQLKLNLDKAQTEEQQAKQDSELAKLRVEEMEQGIAEDVSVAAKAQLEVAKARHTTAITELSSVKEELETLHKEYDALVQDKDVAVKKVEEAMLASKEVEKTVEELTIELIATKESLESAHASHLEAEEQRIGAAMARDQDTHRWEKELKQAEEELQRLNQQIHSSKDLKSKLDTASALLLDLKAELVAYMESKLKQEACDSTTNTDPSTENMSHPDLHAAVASAKKELEEVNVNIEKAAAEVSCLKLASSSLQLELEKEKSTLASIKQREGMASIAVASIEAEIDRTRSEIASVQSKEKDAREKMVELPKQLQQAAEEADEAKSLAEVAREELRKAKEEAEQAKAGASTMESRLFAAQKEIEAAKASERLALAAIKALEESESTLKANDTDSPRSVTLSLEEYYELSKRAHEAEELANARVAAAVSRIEEAKETEMRSLEKLEEVNRDMDARKKALKEATEKAEKAKEGKLGVEQELRKWRAEHEQKRKAGDGVNTEKNLKESFEGGKMEQSPEAVVYASSPSESYGTEENSETNLSPQTKSRKKKKKLSFPRFFMFLSKKKSHNN
Protein: RH35480p (Q8SX05)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPPKKPTEKSAKPGDKKPEQKKTAAAPAAGKKEAAPSAAKPAAAAPKKAAAPAAKKAAPAAKKPATAGAAAKKPAAVKTTAAAKAKSKDAKKKVLAGKKPQSVLAKLSAKARAAAKAKKGVKPVTKPAKGTAKAKAVALLNARRSRRRSSRAPSAPVPARSAPTCTSVGQPP
Protein: guanylate kinase (EC 2.7.4.8) (A0A8I6GLP0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MLRRPLVGLAVAALGRVPVDGMAGPRPVVLSGPSGAGKSTLLKKLFQEHGSVFGFSVSHTTRNPRPGEEDGKDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTRSLLGSTGLLPFPAPSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLHPIYISVQPPSMDVLEQRLRQRNTETEESLAKRLAAAQADMESSKEPGLFDLVIVNDNLDEAYVTLKQALSEEIKKAEGTEHA
Protein: Down syndrome cell adhesion molecule 1, isoform AW (Q0E9L7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVHQFYQTRVIDEFVLRGNSATLKCLVPSFVADFIDVEGWIDEEGVEILRPLPDDSVDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIGSKAPSVPTGVMVFQQQVPLLSTFAMLCQAQAFPVPVFRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVAPKIASFDFGEEPLNYGEPASVQCTILGGDLPMNVTWLLNNATIDSFHDISFSRIGKRINVLSIESVSAHHAGFYSCHAQNKAGITAHSARLIVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Ribosome biogenesis protein UTP30 (U3 snoRNP-associated protein UTP30) (P36144)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in rRNA-processing and ribosome biosynthesis.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 22
- Ribosome biogenesis protein BMS1
- Periodic tryptophan protein 2
- U3 small nucleolar RNA-associated protein 18
- Essential nuclear protein 1
- KRR1 small subunit processome component
- Nucleolar protein 58
- Nucleolar complex protein 4
- Protein BFR2
- Ribosome biogenesis protein ENP2
Sequence:
MVESNDIIKSGLAEKALKALILQCEENPSLKNDKDIHIIINTGKKMGINRDNIPRIIPLTKYKLFKPRDLNILLITKDPSALYRETLTKDEHTSELFKEIISVKNLRRRFKGSKLTQLYKDFDLVVADYRVHHLLPEVLGSRFYHGSKKLPYMIRMSKEVKLKRQQMVEKCDPIYVRAQLRSICKNTSYIPNNDNCLSVRVGYIQKHSIPEILQNIQDTINFLTDKSKRPQGGVIKGGIISIFVKTSNSTSLPIYQFSEARENQKNEDLSDIKL
Protein: LD11641p (NTPDase 6) (NTPase (EC 3.6.1.42, EC 3.6.1.6, EC 3.6.1.64)) (O76268)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKYEYKLLATDEKPPRRKSSGSPNASSGGNRGPSGLKISFLCLIISVILLLFVFGFVSENASPYLARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAFIPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSEFSVDMDAVEIMDGTDEGIFSWFTVNFLLGRLSKTNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAARHAVFTHGYKKEDTVLESVCVNPIIANRTWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFTLKQHAVAAFSYYFERAIESGLVDPLAGGETTVEAYRKKAQEICAIPNDEQPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVLTSDEKFSNS
Protein: Ras-related protein Rab-2A (EC 3.6.5.2) (P61019)
Organism: Homo sapiens (Human)
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi.
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:17081065}; Lipid-anchor {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000305}. Melanosome {ECO:0000269|PubMed:17081065}. Endoplasmic reticulum membrane {ECO:0000305}; Lipid-anchor {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000305}. Golgi apparatus membrane {ECO:0000305}; Lipid-anchor {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:P53994}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000250|UniProtKB:P53994}; Lipid-anchor {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000305}. Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). {ECO:0000250|UniProtKB:P53994, ECO:0000269|PubMed:17081065}.
Interaction partners:
- Golgin-45
- Golgi reassembly-stacking protein 2
- Solute carrier family 2, facilitated glucose transporter member 4
- TBC1 domain family member 1
- Golgin subfamily A member 2
- Islet cell autoantigen 1
- Vam6/Vps39-like protein
- Ras-related protein Rab-1A
- Ras-related protein Rab-1B
- LIM/homeobox protein Lhx6
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
Protein: Dof zinc finger protein DOF1.1 (AtDOF1.1) (OBF-binding protein 2) (Protein PHLOEM EARLY DOF OBP2) (Protein UAS-TAGGED ROOT PATTERNING 3) (Q8L9V6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence. Enhances the DNA binding of OBF transcription factors to OCS elements (By similarity). Involved in the regulation of root development. The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements. Element of a regulatory network controlling indole glucosinolates (IGS) biosynthesis, probably by inducing the expression of accurate genes (e.g. CYP83B1). Promotes apical dominance.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein IQ-DOMAIN 1
- Protein IQ-DOMAIN 11
- Transcription factor MYB34
- Transcription factor MYB28
- Transcription factor MYB51
- At1g31750
- Transcription factor MYB29
- RING/U-box superfamily protein
- Transcription factor MYB76
- Transcription factor MYB122
Sequence:
MPTNSNHQHHLQHQLNENGSIISGHGLVLSHQLPPLQANPNPNHHHVATSAGLPSRMGGSMAERARQANIPPLAGPLKCPRCDSSNTKFCYYNNYNLTQPRHFCKGCRRYWTQGGALRNVPVGGGCRRNNKKGKNGNLKSSSSSSKQSSSVNAQSPSSGQLRTNHQFPFSPTLYNLTQLGGIGLNLAATNGNNQAHQIGSSLMMSDLGFLHGRNTSTPMTGNIHENNNNNNNENNLMASVGSLSPFALFDPTTGLYAFQNDGNIGNNVGISGSSTSMVDSRVYQTPPVKMEEQPNLANLSRPVSGLTSPGNQTNQYFWPGSDFSGPSNDLL
Protein: Endoglucanase (EC 3.2.1.4) (Q6RSN8)
Organism: Acetivibrio thermocellus (Hungateiclostridium thermocellum) (Clostridium thermocellum)
Interaction partners:
Sequence:
YILPQPDVRVNQVGYLPEGKKVATVVCNSTQPVKWQLKNAAGVVVLEGYTEPKGLDKDSQDYVHWLDFSDFATEGIGYYFELPTVNSPTNYSHPFDIRKDIYTQMKYDALAFFYHKRSGIPIEMPYAGGEQWTRPAGHIGIEPNKGDTNVPTWPQDDEYAGIPQKNYTKDVTGGWYDAGDHGKYVVNGGIAVWTLMNMYERAKIRGLDNWGPYRDGGMNIPEQNNGYPDILDEARWEIEFFKKMQVTEKEDPSIAGMVHHKIHDFRWTALGMLPHEDPQPRYLRPVSTAATLNFAATLAQSARLWKDYDPTFAADCLEKAEIAWQAALKHPDIYAEYTPGSGGPGGGPYNDDYVGDEFYWAACELYVTTGKDEYKNYLMNSPHYLEMPAKMGENGGANGEDNGLWGCFTWGTTQGLGTITLALVENGLPATDIQKARNNIAKAADRWLENIEEQGYRLPIKQAEDERGGYPWGSNSFILNQMIVMGYAYDFTGDSKYLDGMFDGISYLLGRNAMDQSYVTGYGERPLQNPHDRFWTPQTSKRFPAPPPGIISGGPNSRFEDPTINAAVKKDTPPQKCFIDHTDSWGTNEITVNWNAPFAWVTAYLDE
Protein: Rab21, isoform A (Q7PLE8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIWDTAGQERFHALGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTDLEEQRAVTHDEALQYARTVGAQYVETSAKENEGVAELFELLTQLMLEQLSQRQPDASPLRLQNPDTDNLNNSDDSEAPDPGDPAGQRSCCGI
Protein: SET domain bifurcated histone lysine methyltransferase 1 (A0A0G2K5A7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription intermediary factor 1-beta
- Activating transcription factor 7 interacting protein
- DNA
- Histone deacetylase 1
- DNA
- Histone-lysine N-methyltransferase
- Cbx5 protein
- DNA
- [histone H3]-lysine
- Histone H3
Sequence:
MKNWKRWTVYSSARSSWQSWRRGCCRRSLREVTNCESLVKDFYSKLGLQYHDSSSDDEASQPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTSTGIQFKPMEPLQPIVPPAPLPMLPLSPQAGDSESLESQLAQSRKQVAKKSTSFRPGSVSSGHSSPTSPTLSENVPPGKIGMNQTYRSPSASVTSTPAPAAPSGPPAPPGPLAPPGPPAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLYLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTVQATACTPGGQINPSSGYQHKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPSSSDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKESELSEVTSKDSRAPDRGPPHVPITPSGSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDSKQSKKEDPEDRNKMSVVTEGSQNHGHNPPMKSEGLRRPASKISMLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTTGQTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
Protein: CUE domain-containing protein 3 (O74485)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation (By similarity). As part of the ribosome quality control trigger (RQT) complex, recognizes specifically ubiquitinated stalled ribosomes (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- RQC trigger complex subunit RQT4 homolog
- RQC trigger complex helicase rqt2
- Uncharacterized protein C15D4.13c
Sequence:
MSENVISSSKNVVSKLLYVKDEYWPSVAPAATELISKLINAFWCQTLNGQLVEEDEGERNCIFLFDRCLKTEGCLKKIGPVTVMQFLACFLLSSQNHAYAWSVCRQIPSDDMAFKFTKCFQNSQQFRDANFCKLVLVWTVCQCVSSTVYYPAILDLLPVLSDLVKEMEKDPASLQAKENEFWLKKLIQTSLHHSSDNSLVFYLEMLLDSLDLRNCIYVVFEDEALFRRLKDIGNPEIRMMLDSGLRDWRKQRSGRSSSHVASKGINKVVNINPGDVKSLIELFPQLSVEEAVEHLSASLGNIDAACESVITSSLPEELDSSTHSPIYTKPNVDSMHKQPKKAIAPLSLSSSVTAVISNRTSDKKTRSTVAEEDDITHLNISPDRLYLNKKPEDLNFWKKSVPETDKSRVLNLLAMAEDDEYDDTYDDLDTTGPVDSGVGDDDPEASSKDAHDFQKFINQTLYDFYQQNPEVFDQKARKSKERADLLAKLDNSLTHEQIEGWRRMFTTDSKFAEAVKKEVTFGSGNTNIGSLRQTKFKQSNYTPPELNDGSRQHRPSRPSKNPSLKKKKYVRTKPKKASNEK
Protein: Protein ATP1B4 (X,K-ATPase subunit beta-m) (X/potassium-transporting ATPase subunit beta-m) (Q99ME6)
Organism: Mus musculus (Mouse)
Function: May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit (By similarity).
Subcellular location: Nucleus inner membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Detected in nuclear envelops. {ECO:0000250}.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit gamma
- Sodium/potassium-transporting ATPase subunit alpha-2
- Sodium/potassium-transporting ATPase subunit alpha-4
- Sodium/potassium-transporting ATPase subunit alpha-3
- Sodium/potassium-transporting ATPase subunit alpha-1
- SNW domain-containing protein 1
- Sodium/potassium-transporting ATPase subunit beta-3
- Sodium/potassium-transporting ATPase subunit beta-1
- Sodium/potassium-transporting ATPase subunit beta-2
- Phospholemman
Sequence:
MRRQLRSRRAPAFPYGYRYRLDDQDEANHNYLADEEEEAEEEAQVMMVPGLEEEEEEEEGKEEEEEREEEEGQGQSTGSAWWRKLQIVNEYLWDPEKRMSLARTGQSRSLILVIYFFFYASLAAVITLFIYMLFLAISPYMPTFTEQVKPPGVMIRPFAHSLNFNFNVSEPETWQRYVISLNGFLQGYNDSLQEEMNIDCPPGRYFIQDGDEDEDKKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPEFGDPVKVSCKVQKGDENDIRSINYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGIVNDVINDRFVGRIIFTLNIET
Protein: Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD) (Q9QY48)
Organism: Mus musculus (Mouse)
Function: Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Subcellular location: Lysosome {ECO:0000305}.
Interaction partners:
- Deoxyribonuclease-2-alpha
Sequence:
MTAKPLRTVLSLLFFALSGVLGTPEISCRNEYGEAVDWFIFYKLPKRTSKASEEAGLQYLYLDSTRQTWNKSLYLINSTRSALGRTLQHLYDTHNSTNDTAYLIYNDGVPGSVNYSRQYGHAKGLLVWNRTQGFWLIHSVPKFPPVHGYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTFHWKLIYMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQKKKQELPSNCSLPYHVYNIKSIGVTSKSYFSSRQDHSKWCVSIKGSANRWTCIGDLNRSLHQALRGGGFICTKNHYIYQAFHKLYLRYGFCK
Protein: MIP13722p (Q9VYH7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GEO10373p1
- Uncharacterized protein
- Chorion protein a at 7F, isoform A
- MIP10102p
- Mucin 4B, isoform B
- IP19013p
- Uncharacterized protein
- RE05851p
- Uncharacterized protein
- IP19005p
Sequence:
MQTQQKRKVSNSRAFTMILILLQVLGILGRGVLAQKSSPIANWHMADPHYTSDQYAKILGEAGLGQDADDKEHKGLGPMQIQYVDYQPNCQPGGVPVCATNGTDSFYFENHCRLEAANMKMLFQHGTELEPTEMERCLPNCQTMKCTQVERPVCALAEIGGAIPQTFANECEMRKHECHTKQVLRILHTGPCQTPTKSGRKKKLRRNKKKRPTLNASISKFATIPKKVYIMLATPAPRSSSTTPRPFFSTTTTRITTTARMRPTKPTSTSPSPMRFQQLMNVANPMVSVSQAIDAYNVYNIPDVGHDYGEITDSSLSMFLPEVGRVTEPYSVPPRTTTKTTSTTRATTTSTTTPKPVLATSRIITPLSTSTMQSFLSVRMPSTTEMVEESTTENPEASTQAFSTTQKSTATAQTKILE
Protein: Cyclin-C (Zgc:73078 protein) (Q6STL0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAGNFWQSSHYLQWVLDKQDLMKERQKDLKFLTEEEYWKLQIFFANVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKTRFSYAFPKEFPFRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYDQWKNFDDRKEIAAVLNKVPKPKPPPNSETDQSSNGSQNSSYSQS
Protein: Superoxide dismutase [Mn] (EC 1.15.1.1) (MnSOD) (Q9RUV2)
Organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Interaction partners:
- Large ribosomal subunit protein bL17
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein uL3
- Chaperone protein DnaJ
- Endoribonuclease YbeY
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL2
Sequence:
MAYTLPQLPYAYDALEPHIDARTMEIHHTKHHQTYVDNANKALEGTEFADLPVEQLIQQLDRVPADKKGALRNNAGGHANHSMFWQIMGQGQGQNGANQPSGELLDAINSAFGSFDAFKQKFEDAAKTRFGSGWAWLVVKDGKLDVVSTANQDNPLMGEAIAGVSGTPILGVDVWEHAYYLNYQNRRPDYLAAFWNVVNWDEVSKRYAAAK
Protein: 3-ketoacyl-CoA synthase 1 (KCS-1) (EC 2.3.1.199) (Very long-chain fatty acid condensing enzyme 1) (VLCFA condensing enzyme 1) (Q9MAM3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Contributes to cuticular wax and suberin biosynthesis. Involved in both decarbonylation and acyl-reduction wax synthesis pathways. Elongase condensing enzyme mostly active with saturated fatty acids, especially with 16:0, 16:1, 18:0, and 20:0. Mediates the synthesis of VLCFAs from 20 to 26 carbons in length (e.g. C20:1, C20, C22, C24 and C26).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18465198}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Very-long-chain 3-oxoacyl-CoA reductase 1
- Protein ECERIFERUM 2
- Very-long-chain aldehyde decarbonylase CER1
- Very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470
- Very-long-chain aldehyde decarbonylase CER3
- Very-long-chain enoyl-CoA reductase
- ABC transporter G family member 12
- Very-long-chain
- Fatty acyl-CoA reductase 3
- Transcription factor MYB96
Sequence:
MERTNSIEMDRERLTAEMAFRDSSSAVIRIRRRLPDLLTSVKLKYVKLGLHNSCNVTTILFFLIILPLTGTVLVQLTGLTFDTFSELWSNQAVQLDTATRLTCLVFLSFVLTLYVANRSKPVYLVDFSCYKPEDERKISVDSFLTMTEENGSFTDDTVQFQQRISNRAGLGDETYLPRGITSTPPKLNMSEARAEAEAVMFGALDSLFEKTGIKPAEVGILIVNCSLFNPTPSLSAMIVNHYKMREDIKSYNLGGMGCSAGLISIDLANNLLKANPNSYAVVVSTENITLNWYFGNDRSMLLCNCIFRMGGAAILLSNRRQDRKKSKYSLVNVVRTHKGSDDKNYNCVYQKEDERGTIGVSLARELMSVAGDALKTNITTLGPMVLPLSEQLMFLISLVKRKMFKLKVKPYIPDFKLAFEHFCIHAGGRAVLDEVQKNLDLKDWHMEPSRMTLHRFGNTSSSSLWYEMAYTEAKGRVKAGDRLWQIAFGSGFKCNSAVWKALRPVSTEEMTGNAWAGSIDQYPVKVVQ