wanglab/gogpt-training-data huggingface dataset:
Protein: Vacuolar calcium ion transporter (Vacuolar Ca(2+)/H(+) exchanger) (O59768)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole (By similarity).
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Calcium-transporting ATPase 2
- Calcium-transporting ATPase 1
- GDT1-like protein C186.05c
- Endoplasmic reticulum transmembrane helix translocase
- Calcium-channel protein cch1
- Uncharacterized membrane protein C1322.03
- Nuclear control of ATPase protein 2
- Phospholipid-transporting ATPase neo1
- Calcineurin subunit B
Sequence:
MIERLKIAKNRLEAMNSFNFPAQDRHERAPLLGSEYDHSMARQLSLLNVVGMTKSVLMSSYFNLMLVFVPIGLIAGWFEWNAKSVFILNMLAIIPLASLLSFATEQLSIISGPTLGALLNASFGNAIELIVGVLALKRGELRIVQSSLLGSILSNLLLVFGMCLVTTGIRREITTFNITVAQTMIAMLALSTATILIPATFHYSLPDNANSENALLHVSRGTAVIVLIVYVLLLVFQLKTHKHVCHDPSEVEEETEPRILGLRSSIAMLAIVTVFVSLCADYLVGSIDQLVEEVNISKTFVGLVILPVVGNAAEHVTAIVVSYRGQMDLALGVAIGSSIQIALFLAPFLVIVGWIISQPLTLYFESLETVILFVSVFLVNYLIQDGATHWLEGVQLLALYAIVVLAFFYYPQ
Protein: Large ribosomal subunit protein eL42 (60S ribosomal protein L42) (Q9UTI8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL8
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL38A
Sequence:
MVNIPKTRKTYCPGKNCRKHTVHRVTQYKKGPDSKLAQGKRRYDRKQSGFGGQTKPVFHKKAKVTKKVVLRLECVSCKYKNQLVLKRCKHFELGGEKKTKGAAIQF
Protein: Tripartite motif-containing protein 59 (EC 2.3.2.27) (RING finger protein 1) (Q922Y2)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin ligase involved in different processes such as development and immune response. Serves as a negative regulator for innate immune signaling pathways by suppressing RLR-induced activation of IRF3/7 and NF-kappa-B via interaction with adapter ECSIT. Regulates autophagy through modulating both the transcription and the ubiquitination of BECN1. On the one hand, regulates the transcription of BECN1 through negatively modulating the NF-kappa-B pathway. On the other hand, regulates TRAF6-mediated 'Lys-63'-linked ubiquitination of BECN1, thus affecting the formation of the BECN1-PIK3C3 complex. In addition, mediates 'Lys-48'-linked ubiquitination of TRAF6 and thereby promotes TRAF6 proteasomal degradation. Acts also as a critical regulator for early embryo development from blastocyst stage to gastrula through modulating F-actin assembly and WASH1 'Lys-63'-linked ubiquitination.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:22588174}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
- Intraflagellar transport protein 80 homolog
Sequence:
MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNFYIWRPLRIPLKCPNCRSIIEIASTGIESLPVNFALRAIIEKYQQEDHPDVVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLKQLTDTHWTDITRLIEKLEEQKCHSEKIVQGDKEVVLQYFKELIDTLEQKKKYFLAALCDVGKMINQEYTPQIQGMKEIREQQLELMTITTSLQDESPLKFLEKIDEVRQRVQMLKQRPLPEVQPVEIYPRVSNVLKEEWSRIEIGRIKKAVIPEMRVSSKRTPCSWSDNDEKEMELFKILNIAIVSLISVILMLILLFNHHIITFLNEITSICFSEVFLSVYQSLSKNLYDLNNTVCYTLYLLKEFMWKIVSR
Protein: Charged multivesicular body protein 2B (A0A8I6AB52)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MNKLTIAILHQCSWSSSFYCVIFDRIIDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACRVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPSASTSKATISDEEIERQLKALGVD
Protein: tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (General control non-derepressible protein 10) (Protein GCD10) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6) (P41814)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Also required for repression of GCN4 mRNA translation by the upstream open reading frames (uORFs) under conditions of amino acid sufficiency.
Subcellular location: Nucleus {ECO:0000269|PubMed:9851972}.
Interaction partners:
- tRNA
- tRNA
- tRNA
- tRNA
- Multifunctional methyltransferase subunit TRM112
- tRNA
- 27S pre-rRNA
- tRNA
- tRNA
- tRNA
Sequence:
MNALTTIDFNQHVIVRLPSKNYKIVELKPNTSVSLGKFGAFEVNDIIGYPFGLTFEIYYDGEEVSSDENRDSKPKNKIPIGKVRLLSQEIKDVNNDKDDGQSEPPLSIKEKSVSLELSSIDSSATNQNLVNMGSKAQELTVEEIEKMKQESLSSKEIIDKIIKSHKSFHNKTVYSQEKYVNRKKQKFAKYFTVEYLSSSNLLQFLIDKGDIQRVLDMSQESMGMLLNLANIQSEGNYLCMDETGGLLVYFLLERMFGGDNESKSKGKVIVIHENEHANLDLLKFANYSEKFIKEHVHTISLLDFFEPPTLQEIQSRFTPLPKEEARALKGGKKNSYYRKLRWYNTQWQILELTGEFLYDGLVMATTLHLPTLVPKLAEKIHGSRPIVCYGQFKETLLELAHTLYSDLRFLAPSILETRCRPYQSIRGKLHPLMTMKGGGGYLMWCHRVIPAPEPVSENATAADSSEKLAEHGAKKQKI
Protein: Cysteine-rich, acidic integral membrane protein (Q38AP5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MSAKYYIPLFMTVLFTSTACVPGMANEAGPIFEESNAEVATPPADAVHDDFFFDYKNATGYADDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCNITGDCNETDDCDITGDCNETDDCNITGDCNETDDCDITGDCNDTEVSDAADGTDGMFLKSSCSLKLVAFCDGCSTEDSPKFSNAKGKGSSVSAGLLLLVGSTFLLLAVGLSAVLFLGRERQNAVVICDNEVMMEEVPRCLSDASFAVPVTQSSDEAKP
Protein: Large ribosomal subunit protein eL14 (60S ribosomal protein L14) (Q54Z09)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein uL22
- Large ribosomal subunit protein eL36
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein eL13
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein eL29
Sequence:
MISKFSLFVEIGRVVVINYGEYINKTAVIIDVLDQNRALVAGPHSGVERHIINFKWINLTPLKVNIQRGARINTLIAAIKAADLETKIAALSAVKKINARATKSNQTDFERFKANLIRRKLNKKVSGEVKKLVNIANRAAHKKAVAQKAAGHVKKTL
Protein: COP9 signalosome complex subunit 6 (OsCSN6) (Signalosome subunit 6) (Q6ZKM2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and response to hormones (Probable). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF (Probable). Involved in early response to iron deficiency.
Interaction partners:
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 1, putative, expressed
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 8
- Os07g0490800 protein
- COP9 signalosome complex subunit 3
- Os01g0279200 protein.
- Os03g0851300 protein
- Eukaryotic translation initiation factor 3 subunit H
- Eukaryotic translation initiation factor 3 subunit M
Sequence:
MSAPSDPAVATHPQAGAAAAASSSSGLTFKLHPLVIVNVSDHHTRVKAQAACSGDGASSAAAGGQPPRVFGCVIGVQRGRTVEIFNSFELVLDPVSGTLDRAFLEKKQELYKKVFPDFYVLGWYSTGSDVRDTDMQIHKALMDINESPVYLLLNPAINLSQKDLPVTIYESELHVIDGSPQLIFVRANYTIETVEAERISVDHVAHLKPSDGGSAATQLAAHLTGIHSAIKMLNSRVRVIHQYLVSMQKGDMPLDNSLLRQVSSLVRRLPAMESEKFQDDFLMEYNDTLLMTYLAMFTNCSSTMNELVEKFNATYERSTARRGGRGAFM
Protein: Possible conserved transmembrane protein (O53651)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable conserved membrane protein
- Carboxyltransferase domain-containing protein
- Possible exported protein
- Probable conserved lipoprotein LpqU
- Probable conserved membrane protein
- Probable conserved transmembrane protein
- Probable transport accessory protein MmpS1
- Probable conserved Mce associated protein
- Probable zinc metalloprotease Zmp1
- Mycoketide-CoA synthase
Sequence:
MRNAWRLVVFDVLAPLATIAALAAIGVLLGWPLWWVSTCSVLVLLVVEGVAINFWLLRRDSVTVGTDDDAPGLRLAVVFLCAAAISAAVVTGYLRWTTPDRDFNRDSREVVHLATGMAETVASFSPSAPAAAVDRAAAMMVPEHAGGFKEQYAKSSADLARRGVTAQAATLAAGVEAIGPSAASVAVILRVSQSIPGQPTSQAARALRVTLTKRGSGWLVLDVTPINAR
Protein: Cation-transporting P-type ATPase N-terminal domain-containing protein (Q5A9B2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Cation-transporting P-type ATPase C-terminal domain-containing protein
Sequence:
MESTYTESTISKLEDKEETIKFDESELEEQSHRGRDKKRRLSFHSRHSSASRHKIFPIRESVDPGSVLPTVFRTISHNIDIEKNHQPIDSSDDNDDKVDKADAAAKTKFSNYSFNSDDIGDIVEKFKTDLTNGLSASQYQENLKTYGINKQSKPPSGLLKRIFMYFFGGFGLLLLVGGVLCIICWKPLGSPPAVANLVLGVILLVVFLIQAGFNFIQDYSSSKVMESIHSLVASEIMCIRDGQKIKISSQDLVPGDIIIFAPGVKIPADARVISNSPDLSFDRAILTGESKPIMATSFSEEPGTNYLESSCIAMQGTFCVNGTGRGIVVSTGDNTIFGSIAQLSSKPKTGLSPLQ
Protein: Type 2 ryanodine receptor (Q99M98)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
VLHIPEENRSVDILELTEQEELLQFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLFPDENKKHGLPGIGLSTSLRPRMCFSSPSFXSXSNECYQYSPEFPLDILKXKTIXMLTEAVKEGSLHARDPVGGTTEFL
Protein: Variable flagella 3 (Coiled-coil domain-containing protein 61) (Q68UI8)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Required for normal flagella and striated fiber formation.
Subcellular location: Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000269|PubMed:32375023}. Note=Localizes to basal bodies and the proximal ends of flagella. {ECO:0000269|PubMed:32375023}.
Interaction partners:
- Basal body protein 10
- Uncharacterized protein
- Caltractin
- Caltractin
- Variable flagellar number protein
- RING-type E3 ubiquitin transferase
- Epsilon tubulin
- Uncharacterized protein
- SAP domain-containing protein
- Uncharacterized protein
Sequence:
MGDICETVEATFHGVAYLLTVSTIEGETLCVEVEQKSDCSRWRGDFTSRYIEDITAKTGNFKKFPVFVKMLLSALKQASDSVFVDLLTYQDLEVLKSRKAGGQAPPPRTQPPNNKRYLIMTYAAEFDRVHYPLPLLFEENPDPQHLKRIISQLRSEVEGLQVEAGNRRGGEVSAELRRLREENAALQRQLKQMERSGSGVGAGAESSEARELARELRTVRKERDLLQARVEAAEAELERERGLHRRELRRRAKEQQELVDELGRCKEQIRELKMRIRQLTEDLEARDRRMNSTDRIRSVYARGSNDGSTSGVAPRRPSSGGRGPSSNYMAPTRGADSRSNSRGRGTSSAERSRPNSAPIGGPRPRFDPTEYVRQRKERESAAVGGRRSNAPTPPRSAGTSRASSVVGSRPASAERLPPIRTASPTNSRPSSTERYRPGSGGPPGRTSAGGSRGAADRAGARGPDPYAPRSRGASPSGRATAWGEPGASGGGAGGWSKFPGGGGGGVGGSGQRISSNSPRSMSPARALAEVKQKLSTFVAGRGGSLQGDDASSAHGEHMSQSSKSQVFEDATAEIADIDSRLHALQNFLRMAKTSSTSTSTTQA
Protein: SIGIRR protein (K9K3G6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MWRCHFILFLTCLANSHSADSLCGSSPEFKHDRTQSVSSTLGHSVVLTCTASMGLNGTDLDCEDHPEWMKDGLQLANLTIYPQNSKEWYTDDEGRMESSELTLTLRDRADFGVYYCIVRNSTAQFTVKEYKSPSHTGAVVASVVMLVVLALAAVVYSKCRLNFKLWYKNIYGEYEINDGKMYDAYISYVNNENDRKFVNFILKPHLENKYSHKLLLNDTNILPGAEPSAELLMNISRCQRLIVVLSQSYLEQEWCTTNFRQGLWHLIELSRKPIFIIFQSQQKQISQDISQQLRQHQPCITMITWGAHSMTPSSGFWKELALVMPRKVTFHRESAGDPQTLLQGDKAPMLTQQPDYLDCRLDPDPAGDLGLRLPIYKTLPPKAPVLPAAPGPTGEAKPSEIDVSDLGLRNYSARRDFYCLVTDDDL
Protein: Zinc finger protein (Q24605)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MENATITTAKHYKTAGKQYKTNKVNNTRRATAAAAAAAAAAATTTVTTAATPTKKRTYRETATATTVTQRSTNKANIAAAIALAAATEATASASASATATATDATLTASKAAATAAATTDAASGNSNSSSKPSTSTRDKLGEVPLPTVDSNHIISNNNNNNNNNNTSNNNNNNHHSDNSISENNYEFKSRDKASLSDSKMTLQQMAAVSSNQEPVAPNVANTMSNSSIINSQQTTVNATPATDEAPLGDRSNISRYLHKKFKRLASTTEVDSWSATNGGGALQASGDAVRTTSLSSNSSLSPPPTTPLANGHHLMTQQQSHQQVQQQQQQQTPPPSVAIHEFSANFVNSNHVNAIGHEESIISNSGYKAAGRTRTPLANSNSNTNSTSNSNSNHAANATLSPASFAQHQQLTQPTTVSPGIPGGAAAPNPACEKSGRYVCQYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYEEPINSPTPSPSTLSAAKSAYIQQPPLPTYMQQLPLGSPAAGTLPPTTADNHHSATAQHRQSIDYKPYKPKFHNASLYSCSSKELQQQQQQLQIQQQQQQHQLAQQKLSIQLPLVQQPSLAHPTLSPSTQMKMKHHINSHQIQLQLQQQQSLLAQQSLLAAMPPGGVYYLGQPSYYNQDTAAAIHQHALAIQQFQIHLAQQQQQQQQQHPPLVKATPPMQQPPSLPPQQLVRANSQISSVATAPATPTPAANLSTFASSSGGKQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNNASQHGSNASALHANNSHNNTNAQMPERETKVNLAQAIFQKQQHQLQQQQQQQITQQQQQQLEQQNYYTYIQQQQECQQQQLEPPNGVVKRNAYKPGVVMTTPVKQQQQLPPPPSPLPMQTMQYRQDPATPVTKIEQPTTAVPVMPLNLSAKPKPTLVTVPVSSLSTSSLAPTPTTSTNPTSSSKTAPPPAQVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICASEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSSLVLSRLSAAQTPARTSTVTAPTVTASAPAPAVATVTAPSSAPAPQIEALRFVDAPLPSPGPLLGKTPLVDYAQQSTPRKAQDSVVITKMHEDRQFVIEAQPAKRIKTSDLVVASSSQQPTSFNFSFNNQNSSNSVPELQSSKEERLRRFTSSGGSMIPISECPDLDNSPKMIRTPLLSGGSFQDVSVKVNNETGSSSKERKLMALVSGSGLLGVSSGPQHFQSPPINSITAFNPLTLPPMSGGDKTTPVTPIPHVPGMPGPGSLTPQMPLLPPPPQQLQLPIPSSRGRSPNRKQPSPLLLGGGSGELKALSPFGGVQNVPSEFSRQPPTPAQRQALQWNSKETPKKAPFNFLRMADNVKTTEPEVRHFNLENVISGKQQELPLTPLHVDTPNGNAPEETSPVASASASAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNGSSTAMAGSGKLSYNLVASQQIVSSPSTSSTSSAFYQGPLKTPPTVTIAALSEANVAAKANEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPPDSEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRQKEHEAARGLLSLSMTPPIPQSVSPYPQLQDTPLPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVANEESAPMDLTKPRGSILLISPSPVSVPAHDLPKSQAQQMHDVIFGTSGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVQLQTYIKEHALHQAKIKQSQFSRSYLINTLYTAASPVMSSSSTLFTANSRPVMSVNEVPSIEVHEVKTPEAIESPRSAPEQAPVILAQIAQEENEEPNIAEPHNANLPAAVQQPDVNEFTGVLVNPTAPPTSSVAPTSTTTAAPVAPSSTANSTQPAQRTVIVGEDGFKSSTPTSKSGDLQHVSYGRGVPPAPIAGDARPTCTMCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLQEKDPGKLSSYTTPSGMMQLAQDAAGPVSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVANGLNHSLKRRLPGSFSSTGEESDNPPESSGEKRARSGQELPVPVAVPVAASAAASN
Protein: Polyadenylate-binding protein (PABP) (E9AFP0)
Organism: Leishmania major
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU362004}.
Interaction partners:
- Probable eukaryotic initiation factor 4A
- Putative eukaryotic translation initiation factor 4 gamma
- ATP-dependent RNA helicase
- ATP-dependent RNA helicase
- ATP-dependent RNA helicase
Sequence:
MAFTGPNPSIWVGGLDPDLQEQKLYDYFVRIGPVTSVRVCVDSATQKSLGYGYVNFQDPADAEKALDQAGSKLGSRYLRIAKIQRDPSKRRSGVNNILVKKLPKSVDTYALKEMFSKFGRLTAIGLACDEKGESRGYARISFEREESAVDAVREMDGMEMDGQAIVVERYQAQHRDELLKQFTNLYVKNLDPAVTDEKLRAFFAKYGEVSSAKVRDLGAAQSEAGLGYVAFQKHENAARAVEELNGKECEIAKAGSPLDVSRFRSREERQRDRERQRRERAQQHSKYPNLYVKGFDDTVTSERLEELFQRYGETVSVTVMMDKETGVSRCFGFVSMKDQNAASQAIQELNGSTFLSPRPLFVTYALRKDARRQNLEERSKQFRVRQNPMGGPGMGAMPPIGFMGPQMFNNVNMPFMNPRVPIMPMNGMNGIGGMNGMGGMNGVGGVGGMGGMGGMGGMGGMGGMGGMGGMGSMGGMGGMARPMAPNAMSQMRSRPMPQKPPMQSLMPQQHQQAPPQGQNLAAVLANLNPEQQKNVLGERLYSYIVRSHPSVAAKITGMLLEMDNAEILNMLDSPTMLDSKIAEAQDVLNRHMSV
Protein: Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (Q9UUB6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.
Subcellular location: Nucleus {ECO:0000269|PubMed:10872838, ECO:0000269|PubMed:15533439}.
Interaction partners:
- 26S proteasome regulatory subunit rpn10
- 26S proteasome regulatory subunit rpn1
- 26S proteasome regulatory subunit rpn11
- 26S proteasome regulatory subunit rpn12
- 26S proteasome regulatory subunit 4 homolog
- Ubiquitin carboxyl-terminal hydrolase 6
- Probable 26S proteasome regulatory subunit rpn6
- 26S proteasome regulatory subunit rpn501
- Probable 26S proteasome regulatory subunit rpn9
- 26S proteasome regulatory subunit rpn8
Sequence:
MSWTTIESDAGVFTDLIENLGVKDVEVDELYSLDVDSLRQFPDIYGIIFLFKWNSKVDKPDGTMDYDSMDNIFFAKQVINNACATQALLSVLLNHSDEIDLGTTLSEFKDFSKTLPPELKGEALGNSEHIRCCHNSFARSDPFISEEVRAATDEDEVYHFIAYTNINNVFYELDGLQAAPINHGSCTKEEFAEKAVSVIQARIANYDPAEIRFNLMVICKDKKASLLTREDLTDEEKAASIAVEDEKRLRWKRENQLRRHNFVGLFVELSKLLVKDRIDKNTWNSTLETAKAKYASQKRP
Protein: Phosphoenolpyruvate carboxylase 1 (PEPC 1) (PEPCase 1) (EC 4.1.1.31) (P04711)
Organism: Zea mays (Maize)
Function: Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Subcellular location: Cytoplasm.
Interaction partners:
- PIT1
- PIT1.
- PIT1
- NADP-dependent malic enzyme, chloroplastic
Sequence:
MASTKAPGPGEKHHSIDAQLRQLVPGKVSEDDKLIEYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKLKKGGFADEGSATTESDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQAEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWPEDKRQEWLLSELRGKRPLLPPDLPQTDEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADENKPAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG
Protein: Anaphase-promoting complex subunit 10 (Q387U5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cell division cycle protein 16, putative
- Cyclosome subunit 1, putative
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 2
- Cdc23 domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Cell division cycle protein, putative
- Uncharacterized protein
- Intraflagellar transport protein 27 homolog
Sequence:
MQFDGRSGGEGDAEGVQGAGAAAVNTPSIVSDDELMALEKRESLIVLQDAVWSVSSAKHGNGVMCLLDGSHNTFWQSDGVVPHVISIDFALLKPVAAVALYLDCAEDNSYTPRRMRVQAGTHNGDMADVATVTVDDPRGWVLIRMQTEAETPSSWNTPAAHSDDAKADIENDMPLDNADFEEFIQDGVWCTRVRVIVEENRQEGRDCHVRGLRVLGHIKQSLFTTASFTQNLHLR
Protein: Transmembrane protein 18 (F4HUY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}. Nucleus membrane {ECO:0000256|ARBA:ARBA00004126}.
Interaction partners:
- Pectinesterase QRT1
Sequence:
MEEIRSAMEKQVDLVADLVEKLSGELRTGFQPAYDNFLGFFHAIDWKEPWIMGLMAFHALLLLVTLLSRRHLNFHMFLFLLACKFPLKLSIYILYKKSLRSNDLTSLVAGVYFAENLNRELRKNWKSFSTQNYFDSNGVFLSTLWSGPLLVIAMIILINTLFSLCYLIVKWKRAELRHRARLAHTKEE
Protein: Uncharacterized trans-sulfuration enzyme YHR112C (P38716)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Cystathionine beta-synthase
- Altered inheritance of mitochondria protein 9, mitochondrial
- Uncharacterized vacuolar membrane protein YML018C
- 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- Probable kynurenine--oxoglutarate transaminase BNA3
Sequence:
MVDLSTALIHGDDKDNRVTDVAPPINVSTTFRYDDDDLIPWTERENLDFMEKKPVYSRLAHPNSTRLESIFSEILDGYAVIYSSGLAAFYAAMVHYNPKKIFIGQSYHGVRAIANILTRNYGIEQHPLEDIEKCASEGDIVHLESPVNPYGTSSDIESLARRAHAKGALLIVDSTFASPPLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIYLGTNVANLESFMLLRSLRTYEMRITKQSENATKLVRFLSDHQSEFDKVLKTIYHSSLQTEEFVKKQLVGGYGPVFAITLYTKEQCKQLPLKLKYFHHATSLGGIESLVEWRAMTDPYIDQTLIRVSVGCESANDLIKDLASALKELQDAA
Protein: Probable carbon monoxyde dehydrogenase (Large chain) (O53708)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable carbon monoxyde dehydrogenase
- Probable carbon monoxyde dehydrogenase
- Carbon monoxide dehydrogenase
- Possible oxidoreductase
- Possible membrane oxidoreductase
- MobA-like NTP transferase domain-containing protein
- VWFA domain-containing protein
- XshC-Cox1 family protein
- Probable transcriptional regulatory protein
- Uncharacterized PPE family protein PPE65
Sequence:
MTTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVKAVVTGADLAAKGLAWMPTLANDVQAVLATDKTRFQGQEVAFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFARDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQKQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPPI
Protein: RNA-directed DNA polymerase (EC 2.7.7.49) (Q8TE30)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTGSNSHITILTLNINGLNSAIKRHRLASWIKSQDPSVCCIQETHLTCRDTHRLKIKGWRKIYQANGKQKKAGVAILVSDKTDFKPTKIKRDKEGHYIMVKGSIQQEELTILNIYAPNTGAPRFIKQVLSDLQRDLDSHTLIMGDFNTPLSTLDRSTRQKVNKDTQELNSALHQADLIDIYRTLHPKSTEYTFFSAPHHTYSKIDHIVGSKALLSKCKRTEIITNYLSDHSAIKLELRIKNLTQSHSTTWKLNNLLLNDYWVHNEMKAEIKMFFETNENNDTTYQNLWDAFKAVCRGKFIALNAYKRKQERSKIDTLTSQLKELEKQEQTHSKASRRQEITKIRAELKEIETQKTLQKINESRSWFFERINKIDRPLARLIKKKREKNQIDTIKNDKGDITTDPTEIQTTIREYYKHLYANKLENLEEMDTFLDTYTLPRLNQEEVESLNRPITGSEIVAIINSLPTKKSPGPDGFTAEFYQRYKEELVPFLLKLFQSIEKEGILPNSFYEASIILIPKPGRDTTKKENFRPISLMNIDAKILNKILANRIQQHIKKLIHHDQVGFIPGMQGWFNIRKSINVIQHINRAKDKNHMIISIDAEKAFDKIQQPFMLKTLNKLGIDGTYFKIIRAIYDKPTANIILNGQKLEAFPLKTGTRQGCPLSPLLFNIVLEVLARAIRQEKEIKGIQLGKEEVKLSLFADDMIVYLENPIVSAQNLLKLISNFSKVSGYKINVQKSQAFLYTNNRQTESQIMGELPFTIASKRIKYLGIQLTRDVKDLFKENYKPLLKEIKEDTNKWKNIPCSWVGRINIVKMAILPKVIYRFNAIPIKLPMTFFTELEKTTLKFIWNQKRARIAKSILSQKNKAGGITLPDFKLYYKATVTKTAWYWYQNRDIDQWNRTEPSEIMPHIYNYLIFDKPEKNKQWGKDSLFNKWCWENWLAICTKLKLDPFLTPYTKINSRWIKDLNVRPKTIKTLEENLGITIQDIGVGKDFMSKTPKAMATKVKIDKWDLIKLKSFCTAKETTIRVNRQPTTWEKIFATYSSDKGLISRIYNELKQIYKKKTNNPIKKWAKDMNRHFSKEDIYAAKKHMKKCSSSLAIREMQIKTTMRYHLTPVRMAIIKKSGNNRCWRGCGEIGTLLHCWWDCKLVQPLWKSVWRFLRDLELEIPFDPAIPLLGIYPNEYKSCCYKDTCTRMFIVALFTIAKTWNQLKCPTMIDWIKKMWHIYTMEYYAAIKNDEFISFVGTWMKLETIILSKLSQEQKTKHRIFSLIGGN