wanglab/gogpt-training-data huggingface dataset:
Protein: INO80 complex subunit D (Q53TQ3)
Organism: Homo sapiens (Human)
Function: Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:18922472}.
Interaction partners:
- INO80 complex subunit E
- INO80 complex subunit C
- Chromatin-remodeling ATPase INO80
- RuvB-like 1
- TCF3 fusion partner
- RuvB-like 2
- INO80 complex subunit B
- Actin-related protein 8
- Nuclear factor related to kappa-B-binding protein
- Microspherule protein 1
Sequence:
MYEGKHIHFSEVDNKPLCSYSPKLCKQRRLNGYAFCIRHVLEDKTAPFKQCEYVAKYNSQRCTNPIPKSEDRRYCNSHLQVLGFIPKKERKKKNDPIDEVKVRHQMDTMAFSLTVPTLALKMPNGLDGMSLSPPGARVPLHYLETELEDPFAFNEEDDDLKKGATVRKKLQSKLAQNRQRQRETEILKVRQEHFSPPPAPSQQQPPQQHSHLSPLSTSLKPPAPPQGSVCKSPQPQNTSLPMQGVAPTTHTIAQARQLSHKRPLPLLPSSRAPTVDPPRTDRILMKATAFSPHFSCISRLQRLVKLCTQKHQLDTDLFPHLGLDWSEESGEEPEDSEQASPYQVAWSIRETLRYQRHASDDDDAESRSSRVTQLCTYFQQKYKHLCRLERAESRQKKCRHTFRKALLQAASKEPECTGQLIQELRRAACSRTSISRTKLREVEPAACSGTVKGEQCANKALPFTRHCFQHILLNHSQQLFSSCTAKFADGQQCSVPVFDITHQTPLCEEHAKKMDNFLRGDNSRKVQHQQQRKPRKKTKPPALTKKHKKKRRRGPRRPQKPIPPAVPQGNLSMPASVSLPVEASHIRSPSTPELSADELPDDIANEITDIPHDLELNQEDFSDVLPRLPDDLQDFDFFEGKNGDLLPTTEEAEELERALQAVTSLECLSTIGVLAQSDGVPVQELSDRGIGVFSTGTGASGIQSLSREVNTDLGELLNGRIVHDNFSSLELDENLLRSATLSNPPTPLAGQIQGQFSAPANVGLTSATLISQSALGERAFPGQFHGLHDGSHASQRPHPAQLLSKADDLITSRQQYSSDHSHSSPHGSHYDSEHVPSPYSDHITSPHTTSYSGDNMAATFSAEMPIMAQHLLPTQLEVPLGGVVNPRTHWGNLPVNLGDPSPFSNLLGADGHLLSTSLSTPPTTSNSETTQPAFATVTPSSSSVLPGLPQTSFSGMGPSAELMASTSPKQQLPQFSAAFGHQLSSHSGIPKDLQPSHSSIAPPTGFTVTGATATSTNNASSPFPSPN
Protein: Zinc finger CW-type PWWP domain protein 1 (Q6IR42)
Organism: Mus musculus (Mouse)
Function: Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3) that facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs). Essential for male fertility and spermatogenesis. Required for meiosis prophase I progression in male but not in female germ cells.
Subcellular location: Nucleus {ECO:0000269|PubMed:31453335, ECO:0000269|PubMed:32374261, ECO:0000269|PubMed:32744506}. Chromosome {ECO:0000269|PubMed:31453335, ECO:0000269|PubMed:32744506}.
Interaction partners:
Sequence:
MMAALQTHKEYEKGTKKTFAPPTQKLHSEKPQPSSWKEDAPGTSSPEAETKPSLLKASLKKEQKPTTEHGPNRGQERKLKAQDQPAKKKGKERTLTSAEFEEIFQIVLQKSLQECLETSSCVQHIRPTKLDEEPGIVPPATDKKDADPEKVITPDTPKIASSLEEEVNSEMGTSKLGQPVTEPSKKKFNRLSLSKQKKKAEDEKMEKIQDGRECSLKEKQKIVIQDQSQIRGPQKEEESGFGHCVIWVQCSSPKCEKWRQLRGNIDPSVLPDDWSCDQNPDPNYNRCDIPEESWAGCESDVAYASYVPGSIIWAKQYGYPWWPGMIEADPDLGEYFLFASHLDSLPSKYHVTFFGETVSRAWIPVRMLKNFQELSLELVKKCKNKNSNQKLEAAIAMAHRAEQTSIQERVNLFGFWSRYNGADISEEGEDLTLCESNNPESCLEKEEKDLEEEKEEEEEKKDPTLPRPKPAKMQTKKPKSRGPAGGPDGTPKKKTAKKSLVSESTVPPVPTLGGKEEQGNSDLDHPVPKKKFKAPENKTSATNLSEEKEIKIVSKCPTPSAQHGACPLGKEGLVPHMPPTQEAASFPPDDDCSSDLDLEQLMEDIGEPEERGEMQQRGSSEEFLAALFEE
Protein: mRNA-capping enzyme subunit beta (EC 3.6.1.74) (mRNA 5'-phosphatase) (mRNA 5'-triphosphate monophosphatase) (O13297)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
Subcellular location: Nucleus.
Interaction partners:
- mRNA-capping enzyme subunit alpha
- mRNA cap guanine-N
- Transcription elongation factor SPT5
- DNA-directed RNA polymerase II subunit RPB1
- SAGA complex/transcription factor TFIID complex subunit TAF12
Sequence:
MSYTDNPPQTKRALSLDDLVNHDENEKVKLQKLSEAANGSRPFAENLESDINQTETGQAAPIDNYKESTGHGSHSQKPKSRKSSNDDEETDTDDEMGASGEINFDSEMDFDYDKQHRNLLSNGSPPMNDGSDANAKLEKPSDDSIHQNSKSDEEQRIPKQGNEGNIASNYITQVPLQKQKQTEKKIAGNAVGSVVKKEEEANAAVDNIFEEKATLQSKKNNIKRDLEVLNEISASSKPSKYRNVPIWAQKWKPTIKALQSINVKDLKIDPSFLNIIPDDDLTKSVQDWVYATIYSIAPELRSFIELEMKFGVIIDAKGPDRVNPPVSSQCVFTELDAHLTPNIDASLFKELSKYIRGISEVTENTGKFSIIESQTRDSVYRVGLSTQRPRFLRMSTDIKTGRVGQFIEKRHVAQLLLYSPKDSYDVKISLNLELPVPDNDPPEKYKSQSPISERTKDRVSYIHNDSCTRIDITKVENHNQNSKSRQSETTHEVELEINTPALLNAFDNITNDSKEYASLIRTFLNNGTIIRRKLSSLSYEIFEGSKKVM
Protein: 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase) (Q02110)
Organism: Sus scrofa (Pig)
Function: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P32755}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P32755}; Peripheral membrane protein {ECO:0000250|UniProtKB:P32755}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P32755}; Peripheral membrane protein {ECO:0000250|UniProtKB:P32755}.
Interaction partners:
- Homogentisate 1,2-dioxygenase
- Tyrosine aminotransferase
- Aspartate aminotransferase, mitochondrial
- Aspartate aminotransferase, cytoplasmic
- Glutamic-oxaloacetic transaminase 1 like 1.
- Fumarylacetoacetase
- Macrophage migration inhibitory factor
- Amine oxidase
- Amine oxidase
- Propionyl-CoA carboxylase beta chain, mitochondrial
Sequence:
MTSYSDKGEKPERGRFLHFHSVTFWVGNAKQAASYYCSKIGFEPLAYKGLETGSREVVSHVVKQDKIVFVFSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAIIVREEVCCAADVRGHHTPLDRARQVWEGTLVEKMTFCLDSRPQPSQTLLHRLLLSKLPKCGLEIIDHIVGNQPDQEMESASQWYMRNLQFHRFWSVDDTQIHTEYSALRSVVMANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRSLRERGVEFLAVPFTYYKQLQEKLKSAKIRVKESIDVLEELKILVDYDEKGYLLQIFTKPMQDRPTVFLEVIQRNNHQGFGAGNFNSLFKAFEEEQELRGNLTDTDPNGVPFRL
Protein: Chitin synthase 5 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase 5) (Class-V chitin synthase 5) (J9VNT4)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Produces a large proportion of the chitin that is not deacetylated to chitosan.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Cell septum {ECO:0000250|UniProtKB:G5EB74}. Cell tip {ECO:0000250|UniProtKB:G5EB74}.
Interaction partners:
Sequence:
MAQQPPPSRFLGVTDLSSLAVTEDTVLVTLQERYISHKPYTSLSPAALVFLSPYSHLPIDDEESLLHYVEEYYQCNNEEGGSRNEQGWWKKKMEQPHVFQLALSAYYNMRRTGQDQVIIASGPTGSGKSELKRLAIEAITQVSLANPGKKGSKIGLQVSSAEFILKCFGNAHTLSNDEASRFGTYTELQFNERGRLEGLKTIVYYFERSRVSQAPINGERNFHAFYYLVSGAPEEERNFLKLGDVSDYRYLNCRVRRVGVDDRHRYSQLRQAFKLMGISSRLIAQIFQLLASILHIGNLRFSPSDGIQEGASVINVETLDIVAEFLGVHSESLAEIFSLKTVLVRKEVCTTFLGPEQAEQVRDELARTLYSLLFSWINEHINTKLCKDSFGSFIALVDLPGIQRNSGSMGSFNSVDQFCLNFAAEKMHNWVLHRVHETTRQEAETERLLISRVPYFDNSECLGMLSNPRGGLISVIDDLSQKKRSESNLLESLGKRFHNHPSMSISPQGNRSSASFTINHYDGPVTYSTSNFLERNANETSTDIIQLLRGDTTSRSQVSTTEGHGSSNPFIKGLFGMKNIAMQTHPRSDSTIVAAQQSVRPVRAPSTRRKKMMSLVPVSEEGGEETSDFQVGGGNDESYSSKELHCIAGQHWAAVDSLLKSFDQTQTWYIFALRPNDSQLPSQFDLRSMKQQVRSFGLVEMAQQLQTSWEVRLSHKEACERYNEELLYRGIPEGTGDVERLRDLKRLMSLNDADMGIGLQRVFLSHDLFRFLEDRLRAKEPGEQHAYEDLGHRKLQTDPFSPHRYQPTSFDSQDHVYKDPSIRPVDSSANLPLMEHAQPIVNSSLEIEDRESSAAPYVSYGGRSITDIEGYASSRDLLASSIHKSEKDPLDTEPQAGETTEVYRESIARRRWVWLCSILTWWIPGFLLSKIAGMKRQDIRQAWREKLAINMIIWFICGCAIFVIAILGPVICPTQHVYSTNELASHSYTLDPNNAFVAIRGEVFDLSQFAPTHLTAVSVVPTKSIMQYGGLDASELLPVQVSALCGGVSGSISQYVTLDSTNTTDVYSQYHDFRAFTNDSRPDWYAEMMIMMRHRFRVGFMGYTKKDLKKMAAQGKAVAIYDNLVYDMSNYIRQNGGGLKAPDGVNLTAQDQADRQFMSDQVVSLFKYNSGKDITTLLDNLGSTIGTDVVDRQKTCLRNLFILGKLDTRDSAQCQFSTYILLALSCVMVAVIGFKFLSALHFGSVRAPESHDKFVICQVPCYTEGEESLRRTIDSLCKLRYDDKRKLILVICDGNIKGFGNDKPTPAIVLDILGVDVNSDPEPLSFQSLGEGAKQHNMGKVYAGLYECAGHVVPYLVVAKVGKPNERQKPGNRGKRDSQMLVMHFLNKVHFSAPMNPLELEMYHQIKNVIGVNPSFYEYLFMVDADTTVDEMSLNRLVSAMRHDKKIIGVCGETSIANAKQSIVTMSQVYEYFISHHLSKAFESLFGSITCLPGCFSMYRLRSPDTNKPLFISHGIIQDYSENRVDTLHLKNLLHLGEDRYLTTLVLKHFQDYKTKFVRHAYAKTVAPDSIKVLLSQRRRWINSTVHNLAELVFLDQLCGFCCFSMRFVVFIDLLSTIIAPVTVAYIVYLIYLIVHDGSSIPTLSIIMLAAIYGLQAMIFIFRMRWDMIAWMIFYICAIPVFSFLLPLYSFWKMDDFSWGSTRLVVGDKGKKIVIHDEGKFDPSSIPLRSWEEYENELWDQESVHSGSYMPPKAEYSYDYPRTRSTYSHGGYAYGQPIHPMQTRSTSPVSSRYQMSQFRQSPYQSPYQGPYGGSTADFRSSRMDMAHRPSLDDTSSFHQPYQPAPRPQSSYAFNLPDPSSDSFTAPAVDYLGAQAITDSQLERSIRKICANAELDKLTKKGVRKELEREYGVELTERREAINRLVEKVLTE
Protein: Palmitoyltransferase (EC 2.3.1.225) (A1ZAR2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Uncharacterized protein, isoform A
- Palmitoyltransferase
- Palmitoyltransferase
- Proteasome subunit beta
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MCPIGEGHRRVPCCAVRWLPALIILGFLVWSYHVFVYQICIKKVSDYLTIGLLLFFYHLLLFMFLWTWFRCIFVAPVRIPDQWKISPEDVDKLKRNDGIEGASRVLNYAARNLPIATCTIDGLVRYCKTCWIIKPDRAHHCRTCHMCVLKMDHHCPWIVNCVHFHNFKYFILFLFYAEVYCFYLFCVMVYDLYLICGFEVTALKNQHSWNILQYLVCILFNIFTVIMYTVSLLNVSRNRTTMESAYATYFLLGGKNNNGFNLGYFVNFRDLYGDKWYLWPFPIFSSRGDGFSFPLAHDRLKEVRTGNQKKDNQPTRTQMYKENMNRILGIHQPPFNEE
Protein: SCP domain-containing protein (G8BL72)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Interaction partners:
Sequence:
MRISTFSSITAILAAAEAAPVIYTNYVTADTTHTNWVTVTTGTTTKTGLTTIYGPPPTATTTSTSSTSSPSSTSSTSSTPAAPSPSSSSSSEVSSTATTPTTSSSSVPETSTQSTSSTTSTTPTTSSSSSSSTTTTSAPTTAPATTTSSSTTTSSTPATSSSSQLSTPSTDAAFANTILAAHNRVRSLHGVQNLSWNDTLAQYAVDYAARTFSCDNVQLVHSGGPYGENLAAGYPGGDSPVNAWYNEIKDYNFDSPGYSSATGHFTQLIWKATSQVGCAYVTCNNAWRQYTICEYYSRGNIVGTDWTTGKSYFEENVLRPVSGEVQLQ
Protein: Small ribosomal subunit protein mS40 (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) (28S ribosomal protein S18b, mitochondrial) (MRP-S18-b) (Mrps18-b) (S18mt-b) (Q99N84)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9Y676}.
Interaction partners:
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein mS22
- Small ribosomal subunit protein mS31
- Small ribosomal subunit protein bS1m
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein mS33
- Small ribosomal subunit protein mS27
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS2m
Sequence:
MAAPLRHTLLKLVPTLLRSSYVAQVPLQTLCTRGPPEEDAPSSLPVSPYESEPWKYLDSEEYHNRYGSRPVWADYRRNHKGGVPPQRTRKTCIRNNKVAGNPCPICRDHKLHVDFRNVKLLEQFVCAHTGIIFHAPYTGVCMKQHKKLTQAIQKARECGLLSYYVPQVEPRDADFGTVHGAVSVTPPAPTLLSGEPWYPWYSWQQPPERELSRLRRLYQGNLLEESGPPPESMPEMPTTPPAESSIEQPGSQSA
Protein: Ferric reduction oxidase 5 (AtFRO5) (EC 1.16.1.7) (Ferric-chelate reductase 5) (Q9FLW2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ferric chelate reductase probably involved in iron reduction in shoots. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates. May act in iron metabolism in reproductive organs. May function as root surface cupric chelate reductase and participate in the reduction of Cu(2+), for Cu(+) acquisition via Cu(+) transporters in response to copper deficiency.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Copper transporter 2
- Squamosa promoter-binding-like protein 7
- Copper transporter 1
- Metal-nicotianamine transporter YSL2
- Zinc transporter 2
- Copper transporter 6
- Fe
Sequence:
MGNMRSLVKMLMVVLFLGWIFVWIMISTNRFQNIWTPKLAKYLKTTYFGPQGMNLVLLTVPMMFIAVLSCVYLHTQKQPSQTQSLYKCREWKVKGRMGRVMMVMNPLGIVTATELTFSLLFLALLVWALSNYLYLSYHVHLHNHDNANDMCRWQAKFRAFGLRIGYVGHYCWAFLFFPVTRASTILPLVGLTSESSIKYHIWLGHVSNFCFLVHTVVFLIYWAMVNKLMETFAWNATYVPNLAGTIAMVIGIAIWVTSLPSFRRKKFEIFFYTHHLYGLYIVFYAIHVGDSWFCMILPNIFLFFIDRYLRFLQSTKRSRLVSAKILPSDNLELTFAKTSGLHYTPTSILFLHVPSISKLQWHPFTITSSSNLEKDTLSVVIRKQGSWTQKLYTHLSSSIDSLEVSTEGPYGPNSFDVSRHDSLILVGGGSGVTPFISVIRELIFQSQNRSTKLPNVLLVCAFKNYHDLAFLDLIFPSDISVSDISKLNLRIEAYITREDKKPETTDDHKLLQTKWFKPQPLDSPISPVLGPNNFLWLGVVILSSFVMFLLLIGIVTRYYIYPVDHNTGSIYNFTYRVLWVMFLGCVCIFISSSIIFLWRKKENKEGDKDSKKQVQSVEFQTPTSSPGSWFHGHERELESVPYQSIVQATSVHFGSKPNLKKILFEAEGSEDVGVMVCGPKKMRHEVAKICSSGLAKNLHFEAISFNW
Protein: 5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2) (P08680)
Organism: Mus musculus (Mouse)
Function: Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. Contributes significantly to heme formation during erythropoiesis (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P22557}; Peripheral membrane protein {ECO:0000250|UniProtKB:P22557}. Mitochondrion {ECO:0000269|PubMed:3557128}. Note=Localizes to the matrix side of the mitochondrion inner membrane. {ECO:0000250|UniProtKB:P22557}.
Interaction partners:
- Delta-aminolevulinic acid dehydratase
- Ferrochelatase, mitochondrial
- Sarcosine dehydrogenase, mitochondrial
- Glycine dehydrogenase
- Peroxisomal sarcosine oxidase
- Serine hydroxymethyltransferase, mitochondrial
- Alanine--glyoxylate aminotransferase
- L-threonine aldolase
- Serine hydroxymethyltransferase, cytosolic
- D-amino-acid oxidase
Sequence:
MVAAAMLLRSCPVLSQGPTGLLGKVAKTYQFLFSIGRCPILATQGPTCSQIHLKATKAGGDSPSWAKSHCPFMLSELQDRKSKIVQRAAPEVQEDVKTFKTDLLSTMDSTTRSHSFPSFQEPEQTEGAVPHLIQNNMTGSQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQHFSEASMASKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGARGAGIGERDGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLSKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLPLQDVSVAACNFCHRPVHFELMSEWERSYFGNMGPQYVTTYA
Protein: Putative actin-28 (EC 3.6.4.-) (Q54HE7)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Actin-related protein 2/3 complex subunit 1
Sequence:
MEINVQAIVIDNGSDTCKAGFVGEEAPRSEFPSIVGIDQNDKDSYVGNEAQSKRGILTLKYPIERGIITNWDDMEKIWHHAFYNELGVAPEENIVVLSESPLNPEENREKMAQIMFETFKTPAIYVENQAVFSIYNSGRMTGIVLDSGDSASHVVPVYEGLALPLATSSLGFAGCDLTDQMSLLLNDLGYNLEREIVRDIKEKLSYVSSDFLWEIDDPSLEKSYELPDGQVITIGKELLACSEGLFLPYVFFGTNLDGIDKAIYNSIMKCDVDIHNDLYGNVVLSGGSTMFPGIEYRMYKELTQLAPSTTEIVINAPPERKNSVWIGGSILGLVPNFPELCFDKEDYDEYGRL
Protein: Regulator of G-protein signaling 20 (A0A8I6GBE3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MALPGRPPRGRRLKLSSPSQELREEDACTGKSSPESPVESEQTEMRMRQMCSGSETQGSVPSQQQGVGGRGSNACCFCWCCCCSCSCLTVRNQEDQRPQRAAHELRTDIPACEESPMPTLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREANKSTIEEKARIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQIYTLMHRDSYPRFMNSTVYKDLLKSLAEKAVEA
Protein: Exocyst component Exo84 C-terminal domain-containing protein (Q95Q35)
Organism: Caenorhabditis elegans
Interaction partners:
- Exocyst complex component 4
- Exocyst complex component 2
- Exocyst complex component 3
- Exocyst complex component 7
- Exocyst complex component 6
- Exocyst complex component 5
- Exocyst complex component 1
- RNA polymerase II-associated protein 3
- Rab8
- small monomeric GTPase
Sequence:
MLSNEDGLFQTDAFSPSDYIRDRLKGVKIGDETRKLRHLRSEMGALNHASQETLKNNVFRNYQQFIDASKEISHLEREIYQLTHSLIEQKQVIENLIMMTGDDKSSIHTVSSHSTTTSTTNPIQILMQKMEGIGGILNNMSTSEKVILYGEMEQFDVETKKPVQKCMLILLSHRLIIGNINAAGKYVMESTLSLNSVAPVNVKDRESGAANAGKVLKLLIFPESRCYLCESARIRTLWFDELEQAKREILHKGSLVRQATIRGKRQTVKERKAAASSAIEEKPSFLEEEEDVGDENEERNDNDISWLSELPAELDDCIAHRDLDQAVELIHEWKQCPTKDAVIDIQLQMRENTIVQLLSDDVSRPGAVHGGPRAMKKARTLLTQLGRGTYATDVYLRRRSAMQRSAMRDVTVSEEPISYVKQLCTLYGNAVSDIANEFRSMPQYYCQVLQWCSYELSTLLNLIRRHVIEVAPAIAVIAYTWKNVMHTMEDLTAIGVHLNFEVNRLLSIPLEKSLQGNFENICDAVKMRISEEKWRPYVLESESALNRLVEELSDVGINVEWAISANDESRSSLNVSQNVVHFAKVAHTLSKDLAPLRLSPIQVLCEVYADELWKMYLQHLADNIRDGAVFAYSTTFILTMVLPVCDKILYGEEGELIRLIDQFPSLAPYADPSDEEKKDDEEVAHV
Protein: DEAD-box ATP-dependent RNA helicase 56 (EC 3.6.4.13) (API5-interacting protein 1) (Q0JM17)
Organism: Oryza sativa subsp. japonica (Rice)
Function: ATP-binding RNA helicase involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus (By similarity). Required for tapetal programmed cell death (PCD) and degeneration during anther development. Forms dimer with AIP2 and binds the promoter region of the cysteine protease CP1. Can complement the yeast RNA helicase SUB2. Plants silencing AIP1 and AIP2 are male sterile.
Subcellular location: Nucleus {ECO:0000269|PubMed:21467577}.
Interaction partners:
- Expressed protein
- THO complex subunit 2
- Os06g0256200 protein
- Os02g0767100 protein
- Os12g0100100 protein
- Os11g0100200 protein
- Os08g0427900 protein
- Os07g0237100 protein
- Os09g0363600 protein
- RNA-binding protein Y14A
Sequence:
MAEAEVKDNEVYEEDLVDYEEEVENGTDGGANAANASADVVKKGYVGIHSSGFRDFLLKPELLRAIQDCGFEHPSEVQHECIPQAILGMDVICQAKSGMGKTAVFVLSSLQQIDPVAGQVGALVLCHTRELAYQICHEFERFSKYLPEVKVAVFYGGVHIKKHKDLLKNDCPHIVVGTPGRILALAREKDLSLKNVRHFILDECDKMLDSLDMRRDVQEIFKMTPHDKQVMMFSATLSKEIRPVCKKFMQDPMEIYVDDEAKLTLHGLVQHYIKLSEAEKNRKLNDLLDALDFNQVVIFVKSVSRAAELNKLLCECNFPAISIHSGMTQEERLTRYKNFKEGHKRILVATDLVGRGIDIERVNIVINYDMPDSADSYLHRVGRAGRFGTKGLAITFVSSASDSDVLNQVQERFEVDIKELPEQIDTSTYMPS
Protein: ADP compounds hydrolase NudE (EC 3.6.1.-) (P45799)
Organism: Escherichia coli (strain K12)
Function: Active on adenosine(5')triphospho(5')adenosine (Ap3A), ADP-ribose, NADH, adenosine(5')diphospho(5')adenosine (Ap2A).
Interaction partners:
- ADP-ribose pyrophosphatase
- Ribose-phosphate pyrophosphokinase
- Uncharacterized protein YhfW
- Phosphopentomutase
- Phosphoglucomutase
- Bifunctional NAD
Sequence:
MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRPTNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGFGANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLEDPDFNEARNVSALFLVREWLKGQGRV
Protein: Angiotensin-converting enzyme-like protein Ace3 (D0G895)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000269|PubMed:20421979}; Multi-pass membrane protein {ECO:0000255}. Note=Disappears from acrosome reacted sperm. Co-localizes with IZUMO1 at acrosomal cap area. {ECO:0000269|PubMed:20421979}.
Interaction partners:
- Kininogen-1
- Angiotensin-converting enzyme
- HMW kininogen-II
- Izumo sperm-egg fusion protein 1
- Angiotensinogen
Sequence:
MNLPWALLLVLLSHRQLLPWLRTVGETSLNDFYSEAQAKLFLQFYEQTAQVVLNEFMEATWNYVTNITKQNQKNMLQKEADRSQFMLYFSTRARMFRTDHFLNQDVKRMLRKLQNIDKSALPTEDLLEYNRLLTYMETAYNRAEVCLDEGPCLTLEPDLQEIMATSRDQKELLWAWQGWRDAVGRQLRPVFEDYVRLSNKAAQYNGYKDMGALWRSKYESDTLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLPYPTKAPEDITAIMKIQHWRPEKMFEEANLFFTSMGMLPAPPAFWIKSMMEKPADGREVECHTSSWNFYKFNDFRVKKCTEVTLEDLLSVFHQMGHIQYFLQYQNLSVIYQEGASPAFEEAVGSVIALSVSSHKYLLARGLLSQPHQDSEEEVNFLLGIALEKIAFIPFSYLVDKFRWKIFDGTISKITYNQEWWNFRLKYQGLCPPVPRSDDDFDPGAKFHIPANVPYIRYFLGLILQFQLHEALCEASGHVGPLHQCDNYNSKVAGKILGDLLKLGSSRPWREVLQEVTGESNISTKAFLTYFKPLMDWLVTENVKQGDTLGWPDFSCSFEEKITSKVSFLGTDTEPEQAYLGQWVLLSMSFFMLVLILALGFRLHYLEKQLLDEDTMILKTLPYSYFLGIAMEPHQAARKQWLLLGLCCILMLCCIGLLIRIVTQNTENTPWMKNEGQS
Protein: Lsm10 (A1Z8C4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- FI05704p
- Small nuclear ribonucleoprotein Sm D3
- Probable small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein F
- Small nuclear ribonucleoprotein-associated protein B
- Probable small nuclear ribonucleoprotein E
- Probable small nuclear ribonucleoprotein G
- Survival motor neuron protein
- RNA helicase
- Gem-associated protein 5
Sequence:
MQQFSAREKYLVSNTLNCWPVMLQGHSVLIDLHNETSVAGIIDVADGHMTCELTHAVFIDRNGGQHPFDHFMVRNRMIRQIHIPSYLDAEQELRSAMERGVLRRKRVETKGGKRTFKQKRAEVRHKETLQMISQQKKNKET
Protein: DEP domain-containing mTOR-interacting protein (hDEPTOR) (DEP domain-containing protein 6) (Q8TB45)
Organism: Homo sapiens (Human)
Function: Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.
Subcellular location: Lysosome membrane {ECO:0000305|PubMed:25936805}. Note=Localizes to the lysosomal membrane when associated with the mTORC1 and mTORC2 complexes. {ECO:0000305|PubMed:25936805}.
Interaction partners:
- Proline-rich AKT1 substrate 1
- Target of rapamycin complex 2 subunit MAPKAP1
- Regulatory-associated protein of mTOR
- Serine/threonine-protein kinase mTOR
- Rapamycin-insensitive companion of mTOR
- Target of rapamycin complex subunit LST8
- Proline-rich protein 5
- TELO2-interacting protein 1 homolog
- Ribosomal protein S6 kinase beta-1
- GTP-binding protein Rheb
Sequence:
MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKDDGTFPLDNEVKAFMRGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEATTRKEAEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQETHDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSPPVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVMEVMEELEC
Protein: Cell division control protein 42 homolog (CDC42Sp) (Q01112)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in development of cell polarity during the cell division cycle.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Serine/threonine-protein kinase shk1/pak1
- Rho GDP-dissociation inhibitor
- Rho guanine nucleotide exchange factor scd1
- Protein scd2/ral3
- Formin-3
- Actin
- Probable Rho-type GTPase-activating protein 4
- Serine/threonine-protein kinase shk2
- Rho guanine nucleotide exchange factor gef1
- Exocyst complex component exo70
Sequence:
MPTIKCVVVGDGAVGKTCLLISYTTNKFPSDYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVTSPASFENVKEKWFPEVHHHCPGVPCLIVGTQIDLRDDPSVQQKLARQHQHPLTHEQGERLARELGAVKYVECSALTQKGLKNVFDEAIVAALDPPVPHKKKSKCLVL
Protein: Cleavage and polyadenylation specificity factor subunit 3-I (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit I) (AtCPSF73-I) (CPSF 73 kDa subunit I) (Q9C952)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. May function as mRNA 3'-end-processing endonuclease and also be involved in the histone 3'-end pre-mRNA processing.
Subcellular location: Nucleus {ECO:0000269|PubMed:16897494, ECO:0000269|PubMed:19573236}.
Interaction partners:
- Flowering time control protein FY
- Cleavage and polyadenylation specificity factor subunit 1
- Cleavage and polyadenylation specificity factor subunit 2
- 30-kDa cleavage and polyadenylation specificity factor 30
- FIP1[V]-like protein
- Cleavage stimulating factor 64
- Cleavage stimulation factor subunit 77
- FIP1[III]-like protein
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- HEAT repeat-containing protein
Sequence:
MASSSTSLKRREQPISRDGDQLIVTPLGAGSEVGRSCVYMSFRGKNILFDCGIHPAYSGMAALPYFDEIDPSSIDVLLITHFHIDHAASLPYFLEKTTFNGRVFMTHATKAIYKLLLTDYVKVSKVSVEDMLFDEQDINKSMDKIEVIDFHQTVEVNGIKFWCYTAGHVLGAAMFMVDIAGVRILYTGDYSREEDRHLRAAELPQFSPDICIIESTSGVQLHQSRHIREKRFTDVIHSTVAQGGRVLIPAFALGRAQELLLILDEYWANHPDLHNIPIYYASPLAKKCMAVYQTYILSMNDRIRNQFANSNPFVFKHISPLNSIDDFNDVGPSVVMATPGGLQSGLSRQLFDSWCSDKKNACIIPGYMVEGTLAKTIINEPKEVTLMNGLTAPLNMQVHYISFSAHADYAQTSTFLKELMPPNIILVHGEANEMMRLKQKLLTEFPDGNTKIMTPKNCESVEMYFNSEKLAKTIGRLAEKTPDVGDTVSGILVKKGFTYQIMAPDELHVFSQLSTATVTQRITIPFVGAFGVIKHRLEKIFESVEFSTDEESGLPALKVHERVTVKQESEKHISLQWSSDPISDMVSDSIVALILNISREVPKIVMEEEDAVKSEEENGKKVEKVIYALLVSLFGDVKLGENGKLVIRVDGNVAQLDKESGEVESEHSGLKERVRVAFERIQSAVKPIPLSAS