wanglab/gogpt-training-data huggingface dataset:
Protein: Complement factor H-related protein C (Q0KHD2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGFCSMLLLSNILLTAWLSTAKGEVKSCEFPQFKYGRLYYEEILRPNFPVSIGNKYSYKCDNGFSPPSGIFWDYLRCTVQGWEPEVPCVRKCVFHYVENGQSAYWEKIYVQGQSLKVQCYNGYSLQNGQDTMTCTENGWSPPPKCIRIKTCSVSDIEIENGFFSESFRTYALNRETSYRCKQGYVTNTGETSGSITCLQNGWSPQPSCIKSCERPVFENSVTKNNSTWFKLNDKLDYECLIGYENEYKHTKGSITCTYYGWSDTPSCYEIECSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHRVGPDSVQCYHFGWSPSFPTCKAGQVASCAQPPEIPNGEINGAKRVEYSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCVEEERTCGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCLSGKWTQLPKCVATDQLEKCRVLKSTDIEAIKPKRKEFQHNSTMYYKCRDKQEYEHSICINGKWNPEPNCIRKISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMCKDGRWQSLPHCIEKIPCSQPPTIEHGSIKLPRTSEKRRKSIEFSSHEHGTTFSYVCDDGFRIPEENGVACYMGKWSTPPRCVGLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCINSRGKCGPPPPIDNGDITSLSLPEYEPFSSVDYQCQKYYLLKGKKTITCRNGKWSEPPTCLHACIIPENIMEARKIILKWRHTKNIYSHSGEDIEFECKYGYHKARGSPPFRTKCISGTINYPTCE
Protein: MATH domain-containing protein (Q585A4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Polyubiquitin, putative
Sequence:
MDPQYSQPLLAPEDQDFYRSILHRLAHESPIRGSTGLDMTLALEKELIRAQENNDSEEYKNVIWGMLKPLVDSLMSAAHRAAPYTYFDNVAPREYPVTRDEEEYFKTDSIFDSDEERGGDDDFDGGSKPMLREQEQSLRKKEELRKKREDDETMLIEQKKVVDDKGTVLNTVGPFAPPRLTVRATTYTFPSRRSLEQRTVPPPAESSSGEDEAGDEEAANVDVTSLCSSGSGEAVSHLTSFMEPLSNDSLKKMSESAKVKVKPSSSNREYIVQIVKTAVRLGCEKACALIDKHKFIEDMTNRVQTGPLQTAASIDFLQSLPEQLKHALSHMLGLWEESPQVEEMWERMVAMGFLAVLTNLRLKPLKRITSELGVSVPDTNSTEKFCEAIVFAAFPRERVRARKSRSKRQKTLAFTVPPSLMRCKGDMGFITFQVENISLLPKDSERRYSPEFEFGQMKWSLLCMANKSNLALYLCQTETVYCKFLISVINHLSKDDSICNEGTQRFFARSQENDWGFNNVARFDELLNPRKGFWHKENDSITIEVGIVIVEAPKTTVSSKNVSNKDKPAGPKVDERAVRQLIEDEKIAQLKKRVKQEISKTLKDEEKTRKDTVQRATKGFHDILERFKSEKQRIVRELAERERREQLERQREQEIIKQAQEQNAEMARGIEEMKRTITNLAREKKELTHDIKELKKAGEKLANELNVIAERKATLLKKIRSYETKISEGQHHLEELQQDPVLSFPVGGESDGIDEIVSAQLQDILERLS
Protein: Sulfotransferase (EC 2.8.2.-) (A8K015)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE
Protein: RNA editing complex protein MP99 (Q86MV6)
Organism: Trypanosoma brucei
Subcellular location: Nucleus, PML body {ECO:0000256|ARBA:ARBA00004322}.
Interaction partners:
Sequence:
MLRRSRLHLLADYRTSSKISDEFNNVLNRSGWGFDHVAVDVGSLSGAAGRLTRDLIGQERDAETVKIIHKQITNVILRRIQPKKSLAIFIDGSEPLWKVRHMRLYPGKKFEGKFYRSAASPMVYSLEDKLRCVGPDLRTPPKEFIVSGPAAPGPVEAKLSAWMLDLATPALPDGAVTTPTVTGAAAAASASAGPPEVTFNDTFCLIGGNDAFLSALGATPFHNITTVTLQQGEMKSLSLSEALEWFAMDHLLKGETSIGSGGNELQKRLASVRTDIVLLYLMANGISATDLPGLGVNFKDLMEAYTAEEANKLYLFGKTSEERCLRMCPLNLERVLTHATRRTSTPTRFCQQSADYLEILLQTHSMICDGGIKNFRWTPNDNDAVPEKQPKIPIERFIGHLKHLAAQGGETTAVADVGSTEPGLAASVDWTFALTGIETLLLSAPKAEMIDQIIPVFTKGHTLPDGVAQDIVDTKNVVEALHKVRRVLQVVVTSDNSGNDDGRIEHPAFNHYPTHYFVRTPGSRGPPPGWTYKSVNLGVRAVALGVRHRVASGMLTAASRVLDSGGVSSKNSLFVFHVKDGITTPSGGGNEDGWLETPCHELAGSSANPASKEISTLRVVTWNVQFSRHSGERTPLGRDGIDWCTSTRYVALAQTLEGLDADVIGMQEVEPAWCKYLSQQPWVREKYAMTCCEHSHAIQPWGVMLLVRRSLCVTSTHHANVPAFSGHTSVMPEVTVVVSEGVPVTVGSMHLLAPYNQNNISNRTTQLDNLTKRLRTRPPINGKQAGLIVMGDFNDCAKNYFTFPPEMGFKDAWLLLHPDEGVSSKSGHTIDGDRNPYAAQIIEKEFYGRADRVLFSSRNLQPIQTEIIGTTSVREMGITKQVDIDKDVPEYLYPSDHFGLLVEFQVV
Protein: Accelerated cell death 11 (Ceramide-1-phosphate transfer protein ACD11) (Glycolipid transfer protein domain-containing protein ACD11) (O64587)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Exhibits selective intermembrane transfer of ceramide-1-phosphate (C1P) and phytoceramide-1-phosphate. Does not transport ceramide (Cer) or GalCer, suggesting a requirement for phosphate in the headgroup for functionality. Transports in vitro sphingosine, but not glycosphingolipids. Has also some in vitro activity with sphingomyelin, a lipid not detected in plant tissues. The transport function may be not directly involved in regulating cell death. Rather, perturbations in the function of ACD11 or related components could be monitored by R-proteins, which then mediate defense and programmed cell death (PCD), as proposed in the guard hypothesis (Probable). C1P transfer is stimulated by phosphatidylserine in C1P source vesicles. Regulates autophagy, inflammasome mediated IL1B and IL18 processing, and pyroptosis, but not apoptosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18845362}.
Interaction partners:
- Binding partner of ACD11 1
- Disease resistance protein LAZ5
- Ceramide kinase
- Phosphatidylinositol:ceramide inositolphosphotransferase 2
- Glycolipid transfer protein 1
- Protein LAZ1
- Probable disease resistance protein At5g04720
- Protein EDS1
- Protein LAZ1 homolog 2
- Protein LAZ1 homolog 1
Sequence:
MADSEADKPLRKISAAFKKLAIIVNSPNPEVPVTQFSHACSLVSPLFGCLGIAFKFAEMDYVAKVDDLVRASSSISTLVVMMDKDIEADCVRKAGSHTRNLLRVKRGLDMVKVLFEQIIASEGDNSLKDPATKSYAQVFAPHHGWAIRKAVSLGMYALPTRAHLLNMLKEDEAAAKIHMQSYVNSSAPLITYLDNLFLSKQLGIDW
Protein: Ethylene-responsive transcription factor 13 (AtERF13) (Ethylene-responsive element-binding factor 13) (EREBP-13) (Q8L9K1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- T-box transcription factor, putative
- Putative glucuronosyltransferase PGSIP8
- Cysteine/Histidine-rich C1 domain family protein
- Protein yippee-like
- Chaperone DnaJ-domain superfamily protein
Sequence:
MSSSDSVNNGVNSRMYFRNPSFSNVILNDNWSDLPLSVDDSQDMAIYNTLRDAVSSGWTPSVPPVTSPAEENKPPATKASGSHAPRQKGMQYRGVRRRPWGKFAAEIRDPKKNGARVWLGTYETPEDAAVAYDRAAFQLRGSKAKLNFPHLIGSCKYEPVRIRPRRRSPEPSVSDQLTSEQKRESHVDDGESSLVVPELDFTVDQFYFDGSLLMDQSECSYSDNRI
Protein: Protease (Q7SSI0)
Organism: Human immunodeficiency virus type 1 (HIV-1)
Interaction partners:
Sequence:
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGSTLNF
Protein: ORMDL sphingolipid biosynthesis regulator 1 (F6WST4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGMYVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPII
Protein: Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (Q9XSZ4)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.
Subcellular location: Basolateral cell membrane {ECO:0000250|UniProtKB:O88343, ECO:0000250|UniProtKB:Q9Y6R1}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:23324180}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Carbonic anhydrase 2
- Sodium/hydrogen exchanger 3
- Sodium/hydrogen exchanger 1
- Solute carrier family 26 member 6
- Solute carrier family 12 member 2
- Solute carrier family 26 member 3
- Solute carrier family 26 member 4
Sequence:
MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKREKERISENYSDKSDVENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREATSLPQLVEMIVDHQIETGLLKPDLKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTSPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHADCEELQRTGRFCGGLIKDLKRKAPFFASDFYDALNIQSLSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDHNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSDFKVGYNTFFSCACVPPDPVNISIANDTTPAPQELSAVSSTDMHQNATFDWAFLSKKECLRYGGKLVGNNCNFVPDVTLMSFILFLGTYTSSMALKKFKTSRYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGGNPWWVYLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVVCSFMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSESKPSDREKSSTFLERHTSC
Protein: Bud site selection protein RAX2 (Revert to axial protein 2) (Q12465)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the maintenance of the bipolar budding pattern. Involved in selecting bud sites at both the distal and proximal poles of daughter cells as well as near previously used division sites on mother cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11110666}; Single-pass type I membrane protein {ECO:0000255}. Bud neck {ECO:0000269|PubMed:11110666}. Bud tip {ECO:0000269|PubMed:11110666, ECO:0000303|PubMed:20678480}. Note=Before cytokinesis, RAX2 concentrates as a ring at the mother-bud neck and to the tip of the bud. The RAX2 ring splits at cytokinesis, endowing each progeny cell with a RAX2 ring and additional RAX2 localization at the distal bud pole of the newborn daughter cell. The rings persist at the cell cortex for several generations, giving rise to cells decorated by multiple rings. {ECO:0000269|PubMed:11110666, ECO:0000269|PubMed:20678480}.
Interaction partners:
- Bud site selection protein RAX1
- Bud site selection protein 9
- Ty transcription activator TEC1
- Bud site selection protein 8
- Protein NBA1
- Axial budding pattern protein 2
- Ras-related protein RSR1
- Bud site selection protein 5
- Nuclear migration protein NUM1
- Bud site selection protein 4
Sequence:
MFVHRLWTLAFPFLVEISKASQLENIKSLLDIEDNVLPNLNISQNNSNAVQILGGVDALSFYEYTGQQNFTKEIGPETSSHGLVYYSNNTYIQLEDASDDTRIDKITPFGVDSFILSGSGTINNISVGNQILYNLSTLSMTPIFNQSLGAVQAVLADNSSIYFGGNFSYNNGSMTGYSALIWDSISNTTQLLPFGGFGENSSVNSIVKLNNDNILFAGQFYTLDDPSALISSSNNGTNSTSSLNATTLELGQRIPLRYASWDSQGSTTFASDSLVCPNTNEDAWLYPDTSGSLVCNLPYEVSPTKIRLYNSQRSDSEISVFQILTDPSSSIMNLTYLDPLSGELKNCGEFCPLYSRATLLSASQNVSSSMDMITFIDNNKTDVKWTSDFQDFAFVNELPVSSLKFVALNSYGGSVGLSGLELYQDTFSTYANDSLNEYGCSALTNDSSSSTLSSNDWYNGLTGESYIAAKYVPDQNEPIPRVKFYPNIIHPGHYTINMYTPGCLQDNTCSARGIVNVTMWNQQNNTIMKTYLIYQNNDNLKYDQIYSGYLDFSPEIVLEYVSGIYTTNTATVVVADQVNVITVSLDAFNTLSDSSNAKKETLLNGILQYQKSNFTSTRLNETKVGNTTLNLFPVKNYPKNSSLYADIYDNKLVIGGVSNRISIVDLNDDFEVTSSKNQTIQGDVHGITKTNQGLLIFGDILSSNNQSAVFLFNGSFENVFNQSRTVNSALNISLANNDFIVLDNDYVVNASSNALIRNSSSFSLSLWAAGNNGDGDVLFSGAVSHMQYGNLNGSVRFLNENEIEPLNLEGGIVPYLGAYLNESATAYAYEVDSLNKIYFSNEVYPSWNWSSGITQMLYADNQTLLAVSAGSSTTAELSIFDLRNLTMIANETLGSNARINALVNFEKNCSMLVGGDFQMTEPNCTGLCLYNYESKTWSTFLNNTIFGEITQLSFTNSSELIISGLFETKEYQSIRLGSFNLTNSTMIPLLSGSEGKLNSFTVTEDSIVAWNDTSLFIYRNQEWNITSLPGNASSISSVSAIYTDIESNTLNKRGINNVNNGSILLLNGNFNISQYGYLQSLLFDFQKWTPYFISETTNTSNYNPIIFINRDVSTEFNSQSPLANVNITVTSPQSTSSQPPSSSASSESKSKSKKKKIGRGFVVLIGLALALGTVSVLGIAGVILAYVFKDPEGDYKPIKPRIDENEMLDTVPPEKLMKFV
Protein: Claudin-15 (Q9Z0S5)
Organism: Mus musculus (Mouse)
Function: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members function as impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN15 forms tight junctions that mediate the paracellular transport of small monovalent cations along a concentration gradient, due to selective permeability for Na(+), Li(+) and K(+) ions, but selects against Cl(-) ions. Plays an important role in paracellular Na(+) transport in the intestine and in Na(+) homeostasis. Required for normal Na(+)-dependent intestinal nutrient uptake.
Subcellular location: Cell junction, tight junction {ECO:0000250|UniProtKB:P56746}. Cell membrane {ECO:0000250|UniProtKB:P56746}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Occludin
- Tight junction protein 1
- Tight junction protein ZO-3
- Claudin-12
- Claudin-16
- Claudin-23
- Claudin-13
- Endothelial cell-selective adhesion molecule
- Claudin-8
- Claudin-2
Sequence:
MSVAVETFGFFMSALGLLMLGLTLSNSYWRVSTVHGNVITTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRCTNVGNMDLSKKAKLLAIAGTLHILAGACGMVAISWYAVNITTDFFNPLYAGTKYELGPALYLGWSASLLSILGGICVFSTCCCSSKEEPATRAGLPYKPSTVVIPRATSDESDISFGKYGKNAYV
Protein: Casein kinase II subunit alpha-3 (CK II) (EC 2.7.11.1) (O64817)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site. The tetrameric holoenzyme CK2 is composed of two alpha and two beta subunits (By similarity). Acts as circadian clock component that maintains the correct period length through phosphorylation of CCA1.
Subcellular location: Nucleus {ECO:0000269|PubMed:16926165, ECO:0000269|PubMed:21735091}. Nucleus, nucleolus {ECO:0000269|PubMed:16926165}. Cytoplasm {ECO:0000269|PubMed:21735091}.
Interaction partners:
- Casein kinase II subunit beta-1
- Casein kinase II subunit beta-3
- Putative casein kinase II subunit beta-4
- Casein kinase II subunit beta-2
- UPF0235 protein At5g63440
- Protein CCA1
- FACT complex subunit SSRP1
- Cysteine proteinase RD21A
- Probable cysteine protease RD21C
- At1g09850
Sequence:
MSKARVYTDVNVVRPKEYWDYESLVVQWGHQDDYEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKKKKIKREIKILQNLCGGPNIVKLYDIVRDEHSKTPSLVFEFVNSVDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTNELDHYLNKYQLDLDPQLEALVGRHVPKPWSKFINADNQHLVSPEAIDFLDKLLQYDHQDRLTAREAMDHPYFAQVKAAESSRLRTQ
Protein: Zonadhesin (Q28983)
Organism: Sus scrofa (Pig)
Function: Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
Subcellular location: Cell membrane; Single-pass type I membrane protein. Note=Exclusively on the apical region of the sperm head. {ECO:0000250}.
Interaction partners:
- Zona pellucida sperm-binding protein 2
- Cysteine rich secretory protein 1
- Acrosin
- small monomeric GTPase
- Hyaluronidase
Sequence:
MLGLPALAGPMAMPHPPLIPSTPTLLAFSFPGGFYMLLDPKNAKPRQRSALLSPLIQSSGCLSLSFQYTQRGQASGATLMVYASVLGSIRKHTLFSGQPGPSWQPVSVNYTSQGQIQFTLVGVFGKIPEPAVAVDAISIAPCEESFPQCDFEDNAHPFCDWVQASQDGGYWRQGNKNTFIQPAGPFGISLNGEGHYIFLETDKFSQAGQSFRLVSRPFCAPAVICVTFTYHMYGLGQGTKLRLLLGSPAGSPPSSLWERVGPQSPEWLNTSVTIPSGHQQPMQLIFEAVRGTNTAFVVALGFVLINHGTCRGPSETSVSTEKPVAPTEKPTVPSEIYTIPTEKPMVHMEKPIVHTEKPTVPTEKPTIPTEKSTVPTKKPTVFKEPTLPPEGPTVPAERPTTPPEGPAVPPKGPTVLTEWPTSHTEKSTVHTEKPILPTGKSTIPTEKPMVPTKRTTTPTERTTIPAEKPTVPIEKPMVPTERTTIPTERTTIPTEKPTVPTEKLTVPTEKPIVPTEKPIVPTEKHTIPTEKLTVLTERTTTPTERTTIPTEKPTVPTEKPSVPTEKPTVPTEEPTIPTEKLTVPTERTTTPTKRTTTPTIRTTTPTIRTTTPTERTTTPTIRTTTPTERTTIPTKKTTVPTEKTIIPTERTIAPTTPQPSPTLVPTQPAAVVMPSTSATTVTPRTTIASCPPNAHFERCACPVSCQSPTPNCELFCKPGCVCDPGFLFSGSHCVNASSCDCFYNDNYYKLGTDWFSPNCTEHCHCRPSSRMECQTFKCGTHTVCQLKNGQYGCHPYGSATCSVYGDPHYLTFDGRRFNFMGKCTYILAQPCGNLTEHFFRVLVKKEERGQEGVSCLSKVYVTLPESTVTLLKGRHTLVGGQRVTLPAIPSRGVFLAPSGRFVELQTAFGLRVRWDGDQQLFVSVPSTFSGKLCGLCGDYDGDSSNDNQKPDGSPAKDEKELGSSWQTSEDADQQCEENQVSPPSCNTALQNTMSGPEFCGQLVAPHGVFEACLPHLRASSFFKSCTFDMCNFQGLQHMLCAHMSALTENCQDAGYTVKPWRGPQFCPLACPRNSRYTLCARLCPDTCHSEFSGRACKDRCVEGCECDPGFVLSGLQCVSRSECGCLDSTAGYVKVGERWFKPGCRQLCICEGNNRTRCVLWRCQAQEFCGQQDGIYGCHAQGSATCTVSGDPHYLTFDGALHHFTGTCTYTLTKPCWLRSLENSFLVSATNEFRGGNLEASYVRAVQVQVFNLRISLIKGRKVTLDGRRVALPLWPAQGRVSITSSGSFILLYTDFGLQVRYDGDHLVEVTVPSSYAGRLCGLCGNYNNNSLDDILQPDKRPASSSVRLGASWKINELSEPGCFAEGGKPPRCLGKEVADAWRKNCDVLMNPQGPFSQCHRVVAPQSSFSSCLYGQCATKGDTLTLCRSLQAYASLCARAGQALTWRNGTFCPLKCPSGSSYSTCANPCPATCLSLNNPSYCPSTLPCAEGCECQKGHILSGTSCVPLSQCGCTTQRGSYHPVGESWYTDNSCSRLCTCSAHNNISCRQASCKPSQMCWPQDGLIRCRVAGMGVCRIPDTSHYVSFDGSYHAVRGNCTYVLVKICHSTMDLPFFKISGENGKREGQPPAFYLRQVYVDIFNTLVTLKQDQVLINGTRVSLPATTQIRGVRVISRDGYTVLTINIGVQVKFDGRGFLEVEIPKAYYGRTCGVCGNFNDEEEDELMMPSDALALDDVMYVDSWRDKEIDPNCQEDDRKTEAESQEQPSANCRPADLERAQEQCQAAFQAPAWANCATRVVLSPYVRSCTHKLCEFGGLNRAFCESLQAFGAACQAQGIKPPVWRNSSFCPLDCSAHSVYTSCVPSCLPSCQDPEGQCTGAGAPSTCEEGCICEPGYVLSEQQCVARSQCGCRDARGTFLPVGRFRLSSGCSQMCVCTAGAIECRPFTCPSGSQCEPNEDGKDFCQPNSSNLCSVFGDPHYRTFDGLSYRFQGRMTYTLVKTLDVLPDGVEPLVVEGRNKVYPSLTPVFLQEIIVMVYGYTVQLQAELELVVNGQKVSIPYKPNEYLQVTLRGRRLYLVTDFELVVSFNGRNNAVIAMPSTYLGLVRGLCGNYDKNKRNDFMLPNGSFTQNLLVFGNSWEVKAKEGHPRFSRAIREEEEKNEESGFQNVSECSPEQLELVNHTQACGVLVDPQGPFAACHQIVAPGPFQEHCVFDLCAAPGPKEQEELRCQVLSGYAIICQESGPTLAGWRDHTHCALPCPANTVYQSCMTPCPASCATLAVPRACDGPCVEGCASLPGYIYSGAQSLPMAHCGCTNNGVYYQQGDSFVTENCSQRCTCASSGVLLCEPLSCRPGEICTLGNLTRGCFRDSPCLQNPCQNDGRCREQGTHFTCECELGYGGDLCTEPRGVPSPKKPEASNRVAILLGMLMPTVLLVPAVTRVSRKRRRRRRPSRERTQSQNRGKRAGTDCAPEQAYKVA
Protein: Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha) (P41374)
Organism: Drosophila melanogaster (Fruit fly)
Function: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This preinitiation complex mediates ribosomal recognition of a start codon during the scanning process of the leader region.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P56286}.
Interaction partners:
- Translation initiation factor eIF2B subunit alpha
- Translation initiation factor eIF2B subunit gamma
- Translation initiation factor eIF2B subunit beta
- non-specific serine/threonine protein kinase
- Translation initiation factor eIF2B subunit epsilon
- 26S proteasome non-ATPase regulatory subunit 14
- Eukaryotic translation initiation factor 2 subunit 3
- Translation initiation factor eIF2B subunit delta
- Eukaryotic translation initiation factor 5
- Eukaryotic translation initiation factor 2 subunit 2
Sequence:
MALTSRFYNERYPEIEDVVMVNVLSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINKLIRVGKTEPVVVIRVDKEKGYIDLSKRRVSPEDVEKCTERFAKAKAINSLLRHVADILGFEGNEKLEDLYQKTAWHFEKKYNNKTVAYDIFKQSVTDPTVFDECNLEPETKEVLLSNIKRKLVSPTVKIRADIECSCYGYEGIDAVKASLTKGLELSTEELPIRINLIAPPLYVMTTSTTKKTDGLKALEVAIEHIRAKTSEYDGEFKVIMAPKLVTAIDEADLARRLERAEAENAQVAGDDDEEDGADQEGMQFDPEKEFNHKGSGAGRANEEDEEEEED
Protein: Arginine/serine-rich protein PNISR (A8XQ35)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEDWTNYHQAQPAESVDWAQLAQQWMAMRDTDDRRAGNSHDFAQNHQLPWHQPRHPGPPAHQDWGDWSANRDEQWRGPPGPSGPSGPPVYHNQGPPRGYPPPPPQGADTWRGAPPPAHHGHFGPPGHHFQGPPQHFPPGPPRPHFPGPPGPHRPPEHYPGPPRPQAPAAPPPKSLFPSAQKPKPLFAAASSAPSFFGAPQRPPPQLHFFQESPSVQHDFQQPDFQPDFQPENYQNSPEPPAQAGPKGVPPPAPLMASGPTNPYAMNKEARKKLPAWILEGLEKAEREKQKQWEKEEKLKKAEEEKARRRAEAGKSKFDSSSDEESPENEKFPVGNGKSEYQEDDNDSEDDLEERREQFIRCVKTLMMNVLLESSNDVIMRIIQEELREHEKLQFERKKLATAPKIIGNSSALAALAAFGDGEDSDNSSDDGVGDDMEPRQESSGSAELNGASGAAEAGTPEAGGGEFKAPIQKTAIIKNRKNRRRKRRENER
Protein: Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2) (Q91ZZ5)
Organism: Mus musculus (Mouse)
Function: Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3) (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Insulin-like 3
- Relaxin-3
- Relaxin-3 receptor 1
- Relaxin-3 receptor 2
- Prorelaxin 1
- Insulin-like peptide INSL5
- Relaxin receptor 1
- Guanine nucleotide-binding protein G
Sequence:
MWLLLHVILLTEVKDFALADSSMVAPLCPKGYFPCGNLTKCLPRAFHCDGVDDCGNGADEDNCGDTSGWTTIFGTVHGNVNKVTLTQECFLSQYPQHCYCRENELECVKADLKAVPKVSSNVTLLSLKKNKIHRLPVKVFSRYTELRKIYLQHNCITHISRRAFLGLHNLQILYLSHNCITSLRPGIFKDLHQLAWLILDDNPITRISQKSFMGLNSLFFLSMVGNRLEALPETLCAQMPQLNWVDLANNGIKYITNSTFLTCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNMITKLPVHLFSDLHLLQKLNLSSNPLLYVHKNQFGSLKQLQSLDLERIEIPNISTGMFQPMKNLSHIYLKTFRYCSYVPHVRICMPSTDGISSSEDLLANGILRVSVWVIAFITCVGNFLVIAVRSLIKAENTTHAMSIKILCCADCLMGVYLFSVGVFDIKYRGQYQKYALLWMESVPCRLLGFLATLSTEVSVLLLTFLTLEKFLVIVFPFSNLRLGKRQTAVALASIWVVGFLIAAVPFTREDYFGNFYGKNGVCFPLHYDQAEDFGSRGYSLGIFLGVNLLAFLVIVISYVTMFCSIHKTALQTAEVRSHIGKEVAVANRFFFIVFSDAICWIPVFVVKILSLLQVEIPGTITSWIVVFFLPVNSALNPILYTLTTSFFKDKLKQLLHKHRRKPIFKVKKKSLSASIVWTDESSLKLGVLSKIALGDSIMKPVSP
Protein: Calponin-homology (CH) domain-containing protein (G5ECY7)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSRPESVLQLARKFGEISAAQENDIHKSRLSLKLGGKENLTKPTLILSKSGPPTPIRHVAPTITHTLPNRPNIGGIASLKSEPKMSRPNMFKQMEKVESNTTTTAPPRQLNPNSIKDALLRWIQNRVAGYPNVNVTNFSSSWADGMAFCALIHRFAPNSFDFSKLDPNNRRYNFDLAFKVAEDNGIFPLLEVDDMIMMGDRPDWKCVFTYVQSFYKQFRDHP
Protein: CAP, isoform B (A1Z871)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPNPIKSAQNSYKNQPGRIENYTTGHSSVSEKEKKENLEQSKLSPLYTEGNLSRALAKESGYTSDSNLVFRKKEVPVSSPLSPVEQKQAYKSLQAGGEPPLLGFRKPAPEKPREILEEFEFIQITPTLTKIRVSTKELEEEVEPVRKAATPPPAPPPPPPPPPHQSLATSRDHKPVKMFSQLSKNLPSFIPLSKKQQVSQQDDPPPRPPHRKSSCTKSTVRVLSSASKSRHEQCFQPPNGTAPGVSTITLRKVATSSCSRREPICRSKSAGAVSTLLQTLTATKETRLTRRVQQQQQQSRLRSSSPSRRPARLLALRHSSRSPVAFGRSISKERSFAEEKKRLENTLPANRTNFEASTNILRDPSLKSPQEVREAVRSYATSRSKSLPRLRHTTVSTTTRQTMCFPQVRPQTLLDCGTRSLRKSSSKTGKGQEKNGSNDSLPRSNSTFSIDSMVRQEIVPIAPPKTYVGKSRGSLSKALVPLQNSRSEGHVPRKRQSGKSTTKPPPPVTVHSYSESVREKTNFWNEYNAKQAMSLPQEYKFCPEDVCDFESHTIQQPCIEDLVWKYEGKEQRPPKQVTVTDIARPQSPQLSQERRFSPTREVRVPQISREVRSPSRRRIDSLRSKDKEQSLARASSLSSADDRKRATPAPSNGLYQCGELAHSATSLTHLERHSPSCRYRNNCERFTELNRFYSTLERVGQLERATSSSSFHPLRKDAELLDFDEWRRVRLHERAEKELQYLVGKLRDDQKQRDLHFRSKDVDSIKWRQEADQSLIAKKKSVEDLRENFEQLNLLRQQQQLQSEPVHRHWRRNTVADLACSLEHQALAEPEMERHLDNDLVSTLSKDQIKKITQQLNEIYSGNRHAPAVEEQYVVTVEKGSRPNGLKVRCNSTISKDQLLGPVQRKRDEQHSNQTLPRSTRSQSPVVVARETRGAIAAKNAELTLTKPPDVPPRPKPTPSQEIKSKPPPKAEPKVEAREPAEDISQKIQYFEDRQFDEPPKTIYHAREDSSPDEAEVMRLINQNMQERQRARQLHHHQELSNSLTDLSGVFGERPAARVNFHLHSPPDRPPDDTELISFGNGSPDHGDGSLELYSDSYYRSRSLSPQSQVSACSSSYLQRVYTGEVRKMRQHFESIQQSGEQSREPSNERRDFFGLSSLRRARSDPEMSAGSKDAPDTVTEAVSKEDVPRLTHKFELRAATPSPERGRKRLRSAQDRLMPHIDIISKTAALKRELPIPVRSSPTRSVSSNSHCFERLRMRYESPEPQTQSYLSTSHPDMRDVHDISPHLSADWVAHKHPEPTKPKDLPKKPQRVVRASSTSPLRPARSQNHQLSSRLTSCMKDIFANQKFDPNKHRPKARYVPDGAENGNQKSKDNGTLERLKKTAMVTFKDVNIHFKTPIRHEQRQNLSEEELAIRQAEHMQKLYHEERRRKYLQELQDMNSRRHTDNFTPSQKSPIALNRYDDFPTDVTLKSLVGPKTVARALFNFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPSKRPSEGQARAKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTSSEPLAYRALYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYVERA
Protein: p-GlycoProtein related (Q17645)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Protein irg-1
- CYtochrome P450 family
- HAlF transporter
Sequence:
MDSFPLLPFSSNTNWSNVCKFIKVIIKCTTRYEKLLFFLGVVFSILTGMCQPFESYTLGETSQVLVKVTNAINNKTIDPVDLAHAYKLFESDMNRVVLLFFLVGFAYFTFGFLQFSIMKFVGDNTAYNVRRQYISRLLRKDISYFDGMSTGHLSIVLNDNMERFREVFNEKIALIIALLTDFVIGTILAFYTDWRLACYGTVFSFGIVLSGLLDSWGKMKNNEKQNEHISNAGSIAFQALGCYKTVSSLNGQQQEVERYTEELKNGEKYALNRAFVFSLSRSADYFFTNALNFVILYFGANMIYEGTIEPGVVVRILYYILFGSYCLGEAILHISRLASAIPLTVPIADILLDSDATADEFFSEEIKDTFQGIISFKNVLFSYPTRPDVPVLKEISFNVQGGECIALVGASGSGKSTVIQLLLHYYNIDSGRISIDGNDIYNINIKQLRQAMGVVFQEPVLFNTSIEENIRFGKPDATEQEIIDALKNANAFDFVCNFPDGIKTIVGERGAQLSGGQKQRIAIARTLVRNPRILLLDEATSALDNESEFIVQEALQKASIGRTTIVVAHRLSTIRNANKIIVMEKGEIVEVGDHKQLIAMNGVYNNLVQTQLMSTNYEKMNENEERVTRQSSHSDFPSNEISHQKIDQEDDYVKKLIAEIKEEGAKKSNICEIIKYCRSEYCILFIAVLGSAIQGIYYPLSSQLMIKSYEAYAFDKDEMLSKSHFWALSILFLAFTRPIFIFFQYYFFGKTAEKLSIKLRSMSFKHLMSLPCAFYDDPCHTATRLSNRLNADSSNVTAAVDDRLGSVIMTLVAILLAVIMSFFYSWKMSLQVLMFCPLLYLAGYCNDNFVDQAVEEDSIAFEKSNRAAIEALENVRTVRALNMENRVILLVTSHLQKIRNSYFKRAVIQGTANGFACSCYFFIYAVSFKFGTWLVLREEILPMDTYLVLMTLSMTASYAGSAVAYLPDHRKAIHAAGLIFHLFTYPAIMPYDSSQGKRNIKNGEIELKNVSFEYAQRSDKMILDGVSLKLPAGRTLALVGPSGSGKSTIISLLERFYHAVDGEVKIDEENVVDVNLHHLRESVSLVSQEPVLFNCSIKENFLFGISHNASQLEIDQALKVANAFSFVSQFPQGLDTLVGERGAQLSGGQKQRIAIARAILRNPKVLLLDEATSALDSDSEKVVQNALDTASERLSTVVVAHRLSTVVNADSIAVLKNGKVAEQGTHEELLRKRSIYWRLVQKQGIQVETLIE