wanglab/gogpt-training-data huggingface dataset:
Protein: Ephrin (Ephrin, isoform B) (Ephrin, isoform C) (LD11109p) (Q9V4E1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- receptor protein-tyrosine kinase
- Roundabout 1, isoform A
- Plexin A, isoform A
- Uncharacterized protein, isoform A
- Roundabout 2, isoform B
- LP22668p
- Neurexin 1, isoform F
- Ankyrin, isoform B
- Serine/threonine-protein kinase CG17528
- Dreadlocks, isoform B
Sequence:
MQERSKQLRLTVSWTQSKSQIHDSCQRRSMLACKRRLTTSKVLEDSHPPVAFPNCKSHRHQQQKEKHKVQLYSGKPLSIKLYVPGSIESIPKIRHKALTTTNKQQPAMHRKSKSKSKFQGFNNLKPLYSPSKRQPPEKHSSVLVEAGIESKASRHFVGKKRIKNRNCLLSSPQPSPMRCKMMIPFPKFGATSFVTLLTLICMETVLLSTMSSCAKTFYMHWNTSNSIFRIDNTDHIIDVNKGNLAFEFDQVHIICPVYEPGTFENETEKYIIYNVSKVEYETCRITNADPRVIAICDKPQKLMFFTITFRPFTPQPGGLEFLPGNDYYFISTSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALSNSKSVTDTGGAINVNIANNDESHVNSHGNNIAIGTNIGINGGQIIGGPQSAGIPINPLSGNNNINGIPTTINSNIDQFNRIPIQPNIIGNHVGTNAVGTGIVGGGGIILTPGHAHGNINMLQPGRGGINGAYPGHHHIQTGIRINNVPTQHNYPSHKGNANSNINGNDDHHHYNKHPNEVVKNEELTYNSGAATSDGNIFALWIWILSIFPLLSIQSCHLSSYWISASFLVSTIAILGIHYLIQITLQTTVQRYSPGMVEITATSMNGMFDQNAGTIEYDR
Protein: MEQ (Meq oncoprotein) (Q80IW5)
Organism: Gallid alphaherpesvirus 2
Interaction partners:
Sequence:
MSQEPEPGAMPYSPADDPSPLDLSLGSTSRRKKRKSHDIPNSPSKHPFPDGLSEEEKQKLERRRKRNRDASRRRRRAQTDYVDKLHEACEELQRANEHLRKEIRDLRTECTSLRAQLACHEPVCPMAVPLTVTLGLLTTPHDPVPEPPICTPPPPSPDEPNAPHCSGSQPPICTPPPPDTEELCAQLCSTPPPISTPHIIYAPGPSPLQPPICTPPPPDAEELCAQLCSTPPPPISTPHIFYAPGLCSTPPPPISTPHIIYAPGPSPLQPPICTPPPPDAEELCAQLCSTPPPPICTPHSLFCPPQPPSPEGIFPALCPVTEPCTPPSPGTVYAQLCPVGQAPLFTPSPPHPAPEPERLYARLTEDPEQDSLYSGQIYIQFPSDTQSTVWWFPGDGRP
Protein: Dehydrin Xero 2 (Low-temperature-induced protein LTI30) (P42758)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Dehydrin ERD10
- Dehydrin ERD14
- 1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal
- Dehydrin HIRD11
- Low-temperature-induced 78 kDa protein
- Probable dehydrin LEA
- Dehydrin family protein
- At4g38410
- At1g16880
- Protein COLD-REGULATED 15A, chloroplastic
Sequence:
MNSHQNQTGVQKKGITEKIMEKLPGHHGPTNTGVVHHEKKGMTEKVMEQLPGHHGATGTGGVHHEKKGMTEKVMEQLPGHHGSHQTGTNTTYGTTNTGGVHHEKKSVTEKVMEKLPGHHGSHQTGTNTAYGTNTNVVHHEKKGIAEKIKEQLPGHHGTHKTGTTTSYGNTGVVHHENKSTMDKIKEKLPGGHH
Protein: AFG2 interacting ribosome maturation factor (V9GYT8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTQDRPLLAVQEALKKCFPVVEEQQGLWQSALRDCQPLLSSLSNLAEQLQAAQNLRFEDVPALRAFPDLKERLRRKQLVAGDIVLDKLGER
Protein: Cyclic AMP receptor 1 (cAMP receptor 1) (P13773)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Receptor for cAMP. Coordinates the aggregation of individual cells into a multicellular organism and regulates the expression of a large number of developmentally regulated genes. The activity of this receptor is mediated by G proteins.
Subcellular location: Membrane {ECO:0000269|PubMed:7876207, ECO:0000269|PubMed:9334341}; Multi-pass membrane protein {ECO:0000269|PubMed:7876207, ECO:0000269|PubMed:9334341}.
Interaction partners:
- Guanine nucleotide-binding protein alpha-2 subunit
- Adenylate cyclase, aggregation specific
- Ras-like protein rasD
- cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase A
- Extracellular signal-regulated kinase 2
- Conditioned medium factor
- 3',5'-cyclic-nucleotide phosphodiesterase regA
- Ras-like protein rasC
- Guanine nucleotide-binding protein alpha-4 subunit
- Guanine nucleotide-binding protein alpha-1 subunit
Sequence:
MGLLDGNPANETSLVLLLFADFSSMLGCMAVLIGFWRLKLLRNHVTKVIACFCATSFCKDFPSTILTLTNTAVNGGFPCYLYAIVITYGSFACWLWTLCLAISIYMLIVKREPEPERFEKYYYLLCWGLPLISTIVMLAKNTVQFVGNWCWIGVSFTGYRFGLFYGPFLFIWAISAVLVGLTSRYTYVVIHNGVSDNKEKHLTYQFKLINYIIVFLVCWVFAVVNRIVNGLNMFPPALNILHTYLSVSHGFWASVTFIYNNPLMWRYFGAKILTVFTFFGYFTDVQKKLEKNKNNNNPSPYSSSRGTSGKTMGGHPTGDDVQCSSDMEQCSLERHPNMVNNQQNLNNNYGLQQNYNDEGSSSSSLSSSDEEKQTVEMQNIQISTSTNGQGNN
Protein: Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5) (Keratin-35) (K35) (Q92764)
Organism: Homo sapiens (Human)
Interaction partners:
- Keratin, type II cuticular Hb5
- Keratin, type I cytoskeletal 27
- Keratin, type II cytoskeletal 71
- Keratin-associated protein 11-1
- Keratin, type I cuticular Ha2
- Keratin-associated protein 3-1
- Keratin, type I cuticular Ha3-II
- Keratin, type I cytoskeletal 25
Sequence:
MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSPSKSCLPCLPAASCGPSAARTNCSPRPICVPCPGGRF
Protein: Oxidation resistance protein 1 (Q7KTR7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MKMCELIVSHGLDREVLSMSTDEYRKTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYRKMARLESPVLIVIEDTEHNVFGALTSCSLHVSDHFYGTGESLLYKFNPSFKVFHWTGENMYFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQEDFVIKTLECWAFV
Protein: 2'-5'-oligoadenylate synthase-like protein 2 (EC 2.7.7.84) (Q5MYT9)
Organism: Rattus norvegicus (Rat)
Function: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Synthesizes oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L (By similarity).
Interaction partners:
- Ubl carboxyl-terminal hydrolase 18
- Interferon-induced protein with tetratricopeptide repeats 1
- 2'-5'-oligoadenylate synthase-like protein 1
- Interferon-induced protein 44
- Antiviral innate immune response receptor RIG-I
- Receptor
- Interferon-induced protein with tetratricopeptide repeats 2
- Ubiquitin-like protein ISG15
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- Interferon regulatory factor 7.
Sequence:
MDTLPDLYGTVGDSLDYFLEHSLQPQRDWKEEGKDAWERIERFFREKCFCDELLLDQEVRVLKVVKGGSSGKGTALNHRSDQDMILFLSCFSSFKQQARDRKAVIDFIKSKLIHCRKSLAYNITVRQHKEGKRTPRSLTLEIQSRKSNDIICMDILPAYNALGSFSRDCKPEPEIYENLIRCKGYPGDFSPSFAELQRHFVKSRPVKLKNLLRLVKFWHLKYLRHKYRRAVLPSKYALELLTIYAWEMGTDSSDNFNLDEGFVAVMELLRDYQDICIYWTKYYDFQNEVVRNFLKEQLKGDRPIILDPADPTNNLGRRGKWELVAKEATYCLLQLCCVTADRWNVQVSIAHYLRGARDVQVTVKQTGREEWILLTNPHSPIRKLKAKIKKRMNLCGELRISFQEPGGERQPLSGRKTLSDYGIFSKVNIRVMETFPPEIQVFVRYPGGQNKPFAIDPDATILSLWEKIEEDGGPCTEDWVLLFEGEELDDDDNLAELQIKDCDTIQLSRVS
Protein: DNA damage-regulated autophagy modulator protein 1 (Zgc:101811) (Q5XJL0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MFWFMEGMCFLPTFLVIWSSSTFIISYIIALYRQDVDVVLPYISDTGATPPESCVFGFMSTITAFAAFATMYAEYKFVERVHERTGAVPPTLNKVSFGFGIFSCIGMCLVATFQETTVMEVHDIGALLFFICGVVYAVIQSVIGYRAFPYGSSKVMCHLRTFFSTVAILAAIPTIACGFLVGTSKLHWDSNDKDYTRHIVSVACEWITTFSFVFFFLTYIQEFQQFTLKLTVNLKEYSGL
Protein: Probable NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2) (Q9USN5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glutamate synthase
- NADP-specific glutamate dehydrogenase
- Glutamine synthetase
- Aspartate aminotransferase, cytoplasmic
- Probable isocitrate dehydrogenase, mitochondrial
- Putative alanine aminotransferase
- Aspartate aminotransferase, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Probable citrate synthase, mitochondrial
- Pyruvate carboxylase
Sequence:
MYLTKQIPHYSRIHTTQLLTVVNHRTIPFKIRGSFSNCRRYSNFATVPLLERPFKNKSKHNTARASRPFSTQKMLLTKSHPPNMYKDSVFFGYRPIVFSGKQDQKSKVIQCLRTERKTIPDDLVEDEVDRFYNKLGLDDYYFQMEPVSIIADHIEIIYAAKIAAHASHAKEELNIHVKNENEDLAIYLDSSPVTQPELDQSSAVEESISTRYLDPFKLTDPTAYRVESFTSVTNIDRTSTENSNIYTYFVTKCDFVDNPKKDASPDVPTDIASVSDKTFLEKASDNTIEMYQDVMNSVLTRFGPVVRLFDYQGRSEIRLVVGYRRGSIFQYFPSLSKLFRYYGLHSTRTYVEQFSNGVTIISYNFKPELFKNAAVTSINELFSQITREASLLYCLPSTDFQPLFVSEKLSIQEVTYAHCVRIFCEHVMNKLGPEYSSLSAILDHSNNIHAEILETIKRRLSTLAFTRTKIHDTIMQYPGLVHTLFEQFYLEHAINHNSTPHLHRAKSATSLADEASTYSITPMSATALMDLIQKTCTNEEDVSVMEMFVKFNTHLLKTNFFQTTKVALSFRFDPSFLDSTQYKDPLYAMIMSIGNEFRGFHLRFRDVARGGIRLIKSANPEAFGLNARGLFDENYNLAKTQMLKNKDIPEGGAKGVILLGKDCQDKPELAFMKYIDSIIDLLIVNKSQPLVDKLGKPEILFMGPDENTADLVNWATIHAHRRNAPWWKSFFTGKKPTMGGIPHDKYGMTSLSVRCYVEGIYKKLNITDPSKLTKVQTGGPDGDLGSNEIKLSNEKYIAVIDGSGVLYDPAGLDRTELLRLADERKTIDHFDAGKLSPEGYRVLVKDTNLKLPNGEIVRNGTIFRNTAHLRYKADTFVPCGGRPNAININNVEQLIDDHGRPAFKYLVEGANLFITQDAKSVLEKAGVIVIRDASANKGGVTSSSLEVLASLSFDDASFKENMCVHDGKVPTFYADYVNEVKRIIQRNANLEFEAIWKGHSENKIPYTSLSNHLSTEIVKLDHDIYNYEKLWADVGFRNAVLRASIPKTLQAKIGLEKMLERIPESYLRAIFSTYLASRFVYQHVVSSDPFAFFDYISTEMKMLKDA
Protein: Centromere protein H isoform 1 (A0A0S2Z5T0)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQLEKNVDMM
Protein: Hydroxyproline-rich glycoprotein family protein (F4I9C1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cytochrome P450 78A6
- Sequence-specific DNA binding transcription factor
- Stearoyl-[acyl-carrier-protein] 9-desaturase 6, chloroplastic
- Guanosine nucleotide diphosphate dissociation inhibitor 2
- Guanosine nucleotide diphosphate dissociation inhibitor At5g09550
- Guanosine nucleotide diphosphate dissociation inhibitor 1
- Transducin family protein / WD-40 repeat family protein
- Vacuolar protein sorting-associated protein 45 homolog
- Probable WRKY transcription factor 7
- Vacuolar sorting protein 18
Sequence:
MADQSGGLVMMREYRKGNWTLNETMVLIEAKRMDDERRMRRSIGLPPPEQQQDIRSNKPAELRWKWIEDYCWRKGCMRSQNQCNDKWDNLMRDYKKVREYERRRVESSITAGESSSSSAPAGETASYWKMEKSERKERSLPSNMLPQTYQALFEVVESKTLPSSTAVTAVTAAVAAAAAAISSGNGSGGGQIQKVIQQGLGFVVPKVHQIIQQQPVLLPLQPPPPPPPSQPLPRPLLLPPPPPPSFHAQPILPTKDSSTDSDTSEYSDTSPAKRRRTMPTTTTAGPSGGGVDVEEVGRSKRDEETTVAAALSRSVSVIANAIRESEERQDRRHKEVMNVQERRLKIEESNVEMNREGMNGLVEAINKLASSIFALASSSRHNN
Protein: Proteasome regulatory non-ATP-ase subunit 10 (Q57YH3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Proteasome regulatory non-ATP-ase subunit 2
- Protease regulatory ATPase subunit 4
- Proteasome subunit alpha type
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome regulatory ATPase subunit 3
- Proteasome alpha 7 subunit
- Proteasome regulatory ATPase subunit 1
- 26S proteasome regulatory subunit RPN3
- Proteasome subunit alpha type
Sequence:
MPEACFLCLDSSEFMRNGDQHPNRFFVVQEAATLLANAKTSANAENTVGFLTLGGNACTVFETLTSDVDRVMSTMSKISISGKQCHFSKGLQIACLALSHRTNPRAEKRIVAFIGTPLGETDGELEKLAKKLRKESVAVDVVSVGVPSNVPRLTAFVERLSNNGNSRFLSVPAKVPLIDSLMSSAIFMGEDSSVSGGGFNGSSAGFSVDPTMDPEMVLAIQMSLEEEERRQAAAAALNSNAAESETVERTDINMDEEALSLENMTEEEMLRRALLLSLQEANKGQAAAGSNATNTADDEAFANELEKELERQSKEETLQGKHDDQNEEKED
Protein: 3-hydroxypropionyl-coenzyme A dehydratase (3-hydroxypropionyl-CoA dehydratase) (EC 4.2.1.116) (A4YI89)
Organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Function: Plays a role in autotrophic carbon fixation via the 3-hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl-CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crotonyl-CoA. Inactive towards (R)-3-hydroxybutyryl-CoA.
Interaction partners:
- 3-hydroxypropionyl-coenzyme A synthetase
- 3-hydroxyacyl-CoA dehydrogenase
- Acryloyl-coenzyme A reductase
- 3-hydroxyacyl-CoA dehydrogenase
- 3-hydroxypropionate dehydrogenase
- Acetyl-CoA acetyltransferase
- Acetyl-CoA acetyltransferase-like protein
- Propanoyl-CoA C-acyltransferase
- Propanoyl-CoA C-acyltransferase
- Acetyl-CoA acetyltransferase-like protein
Sequence:
MEFETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAFCAGADITQFNQLTPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACDIRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVNRVVPLANLEQETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFSTEDKKEGVSAFLEKREPTFKGK
Protein: E protein (Q7D2R8)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Interaction partners:
Sequence:
MMVPPRPGFAPLSLESINDRMEMHLFLTSACILYHIYIRDNLLIYQEIWTKYWRGRLAESALKNEISALYLRLPFPRPPTLQSIAEQEVICKDAAPIYVYCSREAMLSHVQSKDLCQFGRANLLACTLAPYRTGVTIEMVRCLFKRLRDGNRVEAGTGEEDLSHFVAFLPTTAFRRGPRFYLGGENVQFFLREGGLELPCHIIAFGRALFSEILADGSSWDWKSVGESSRLNHVRASVELSRNVPTAETTDNWAEAALGTDAVYPVRPPNLTPTQDHPCKPLLSGNRVPNERHRPWKRFFKKLRSVSKHFYFNR
Protein: Protein lozenge (Q9W349)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in prepatterning photoreceptor precursors in the developing eye; in the larval eye disk it defines a subset of cells as an equipotential group that is competent to respond to the sevenless developmental signal and another subset that confer proper photoreceptor identity by positively regulating the homeo box gene Bar. Involved in the aop/pnt dynamic in a Ras-dependent manner to regulate pros expression. Promotes apoptosis in the pupal eye by directly activating aos and klu. Also modulates hid- and rpr-mediated cell death. Regulates amos function in olfactory sensilla development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00399}.
Interaction partners:
- Protein big brother
- Box A-binding factor
- Myeloid leukemia factor
- Shaven, isoform A
- ETS-like protein pointed
- Polyhomeotic distal, isoform A
- Ets DNA-binding protein pokkuri
Sequence:
MHLHLLAAEKTPPSPSPNPTPTPSASPSGHTGAAGESQLDLASQTESQLQLGLPLASGYGLGLGLGLGLGLGLGQELVADHSTTVAPVSVAGPGRLGRSINGSGGSHHHHHLHHHYSPYHHAHPYHPPHPHAPHHHHHHHPPYPYPPAGPHPPAMVTSSSTSPTGNGWSSSTGDFKGITAVATATGGGVGGATQGATASTGATAAEVLAVSSSASVGSSSPTGGASNGTAHSGHSGHTGGHSSSTASNNNNNGASNSNSNNNNAVHQDLLWMERLVQKRQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPRSKTSPTGGPHYRALGLGQRPYIDGFPSTKALHELESLRRSAKVAAVTTAAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSNYSSPNSTINSDCQVYKPNAPHIQAAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAHHAHAHLQHQMALPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGYDSANSLEAGQYAAHLPAVLPEMHGHGFATDPYQTAGYGGGNTGGGSASKSELDYGGSYNQAWSNGYQNYQYGSCLATAQYGPQAAPPPQPPPPPPVVLCPQLYSTVNQNQIHLHLHSSEKLEQYLGTATSADHLTIGSLTGSSRSSIEIGQDQYHQQVHHAQQQQQQQQQQQQVHHPQQQQVESAGEVGGSGAGGVESAREEDVGDLSQVWRPY
Protein: ABC transporter B family member 12 (ABC transporter ABCB.12) (AtABCB12) (Multidrug resistance protein 16) (P-glycoprotein 12) (Q9FWX8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
Sequence:
MNRDGAGEGDSVSHEHSTSKTDEKAKTVPLYKLFAFADSFDVFLMICGSLGAIGNGVCLPLMTLLFGDLIDSFGKNQNNKDIVDVVSKVCLKFVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTILRQDIGFFDVETNTGEVVGRMSGDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAMALLVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKYITSAYKSSIQQGFSTGLGLGVMIYVFFSSYALAIWFGGKMILEKGYTGGSVINVIIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLIDGINLKEFQLKWIRSKIGLVCQEPVLFSSSIMENIAYGKENATLQEIKVATELANAAKFINNLPQGLDTKVGEHGTQLSGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALDRVMVNRTTVVVAHRLSTVRNADMIAVIHSGKMVEKGSHSELLKDSVGAYSQLIRCQEINKGHDAKPSDMASGSSFRNSNLNISREGSVISGGTSSFGNSSRHHSLNVLGLFAGLDLGSGSQRVGQEETGTTSQEPLRKVSLTRIAALNKPEIPVLLLGTVVAAINGAIFPLFGILISRVIEAFFKPADQLKKDSRFWAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSGTMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPLIGINGFLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGPIKDGVKQGFISGLGFGFSFFILFCVYATSFYAAARLVEDGKTTFIDVFQVFFALTMAAIGISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPARPGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQLKWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYDTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNRTTVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIKIDGGVYASLVQLHMTASN
Protein: Activator of transcription and developmental regulator AUTS2 a (Autism susceptibility candidate 2a variant 1c) (Autism susceptibility candidate 2a variant 1d) (Autism susceptibility gene 2 protein isoform X2) (A0A1X9RK87)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDGPRCSGIRKKRKSRSVRNRERISNGIRNNHVRGSVLRFSSDSEKEDGSTNPSSSSRPRPPRRKRKESSSAEEDIIDGFSIAGFMTLEALEKDMTLKPHERRQNQAGPLRKKKPGRVANGLSLDLHKDRLNHSNHQHSDQENNPRLARTHSKKKKKKHLQKKHRPLKPGQNNCKDSDSESVSGESKPSIRSSSRDRLTDCDSESDQEDKGSDASSEKLFSTAAVKVPDFSVDTLSTNASQELRGLGIPKVSGLERSQEKSQETSREISSATPPLVPTSHSKPPLPAPLHLQPPPSSRGLPLPSRPAQIQNPCPERTLRPLSPPIALPQSQGQELSQAPPHPSQHPPESPSHPKPPRTPSIYHHPPSPALPAQQNPTQPVQHRPPSRCHQRPISAYSGSLTLNGLSSRSSTPGKPPGPSPAPHLHHHQPAPTGASASFPLPLSANPTASHTFPPSLPSSTLPHHTNMFASPAALPPPPPLTSNTLPVPGHPAGSAYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHQHQHTHQHTHQHTFTPFPHAIMPTPAPPMVRTPARNFEKYPTKVDPFYRHSLFHSYPPAVSGIPPVIPPTGPFGSLQGAFQPKTSNPLDVAARPGAVPHTLLQKDPRLTDPFRPVLRKPGKWCAMHVHIAWQIYHHQQKVKQQMQVDPHKLDFGLKPEFLSRPPGPTLFGAIHHPHDLARPASLFSAAGSTHPAAAPFGHPPHHPSNFLTPAPHLEPFSRPPSFGGLASLSTAAFGGLGNPALASNSVFGHKDSPSAQQHFSGPHEPWNRLHRTPPSFPTPPPWLKPGESERSASVSSHERERERDRERERDLDKRDSSVNKDDKEREPVEKRHQNHQSPLPVNPLTLLGHTRPSEPSRNHISSSEPRDKDKDKPKDRERDREHSDWKDSNTDEHKLKENHHSDKDTPVIHDGRVSEDKPANRITASPYMRPGGMDRVNGGLTRDILEKKAEITYEKKNSEVKVKEERKEEQDGPTERSPEQRSTPQAPPPPPPAALHPPSSMPVPMGMASMHPINSISSLERTRMVAPFMGISPIPGAERFPYPAFHWDPMRDPYRGLDIHRRDPLARELLLRNDPLHRLAAPRLYEAERSYRDREPHDFNRDHPHGLTLEQRREQERAHLEERERLHLLREDYEQGRLHPMHHPVLDGHLPHPGLMAPGLPSMHYPRVSPSSAVAAAAQNGILNKTPPTASLSAPPPLIPTLGARSSSPRRTTPLGPDIRDRPPSHTHKDIEAR
Protein: Sodium-dependent proline transporter (Solute carrier family 6 member 7) (P28573)
Organism: Rattus norvegicus (Rat)
Function: Brain specific sodium (and chloride)-dependent proline transporter. Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals (Probable).
Subcellular location: Synaptic cell membrane {ECO:0000250|UniProtKB:Q99884}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized protein.
- Prothymosin alpha
Sequence:
MKKLQEAHLRKPVTPDLLMTPSDQGDVDLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCGNWWNTERCLEHRGPKDGNGALPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVIYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAIDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEEESMM
Protein: COMM domain containing 5 (E9PJE4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSAVGAATPYLHHPGDSHSGRVSFLGAQLPPEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCREAVQRLGVSANLPEEQLGALLAGMHTLLQQALRLPPTSLKPDTFRDQLQELCIPQDLVGDLASVVFGSQRPLLDSVAQQQGAWLPHVADFRWRVDVAISTSALARS
Protein: Retinoic acid receptor RXR-beta (MHC class I regulatory element-binding protein H-2RIIBP) (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta) (P28704)
Organism: Mus musculus (Mouse)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P28702}. Cytoplasm {ECO:0000250|UniProtKB:P28702}.
Interaction partners:
- Oxysterols receptor LXR-alpha
- Oxysterols receptor LXR-beta
- Retinoic acid receptor alpha
- Retinoic acid receptor beta
- Peroxisome proliferator-activated receptor gamma
- Retinoic acid receptor RXR-gamma
- Peroxisome proliferator-activated receptor alpha
- Peroxisome proliferator-activated receptor delta
- Retinoic acid receptor RXR-alpha
- Nuclear receptor coactivator 2
Sequence:
MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
Protein: Evasin P1077 (A0A090XE98)
Organism: Ixodes ricinus (Common tick) (Acarus ricinus)
Function: Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL3, CXCL5, CXCL6 and CXCL11.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
KVKTFAFLQIVVLIALSLHLASAGSKQLIGPQSSTNSIKAEFCDTNCTAGTNGIWNGCSGDCFCTHVGNSTEGRCMKITGFDEYPTSEAEE
Protein: Auxin-responsive protein SAUR63 (Protein SMALL AUXIN UP RNA 63) (F4I1H5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22507274}; Peripheral membrane protein {ECO:0000305|PubMed:22507274}. Note=Localizes in a punctate pattern at the plasma membrane. {ECO:0000269|PubMed:22507274}.
Interaction partners:
- Auxin-responsive protein SAUR19
- Auxin-responsive protein SAUR20
- Auxin-responsive protein SAUR41
- Auxin-responsive protein SAUR76
- At4g38840
- Cytochrome oxidase complex assembly protein
- Protein ROOT HAIR SPECIFIC 17
- Arogenate dehydrogenase 2, chloroplastic
- Protein SMALL AUXIN UP-REGULATED RNA 16
- Auxin-responsive protein SAUR21
Sequence:
MINAKKLMKMAKKWQQRAALHRKRISFQRSSVFTSSSSTVEKGCFVVYTADKIRFAFPISYLSNSVVQELLKISEEDFGLPTEGPITLPFDSAFLEYLVKLIQRRMDEDTEKALLLSISSARCSFQPQEQQCSTTQQLLVF
Protein: Neuroglobin (Nitrite reductase) (EC 1.7.-.-) (Q9ER97)
Organism: Mus musculus (Mouse)
Function: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:22659017}. Mitochondrion matrix {ECO:0000269|PubMed:22659017}. Note=Enriched in mitochondrial matrix upon oxygen-glucose deprivation. {ECO:0000269|PubMed:22659017}.
Interaction partners:
- Cytoglobin
- Myoglobin
- Androglobin
- Cytochrome c, testis-specific
- Cytochrome c, somatic
- Flotillin-1
Sequence:
MERPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKCLGPDFTPATRTAWSRLYGAVVQAMSRGWDGE