wanglab/gogpt-training-data huggingface dataset:
Protein: Serine carboxypeptidase-like 45 (EC 3.4.16.-) (Q93Y09)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable carboxypeptidase.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Subtilisin-like protease SBT4.14
- F-box protein At1g70590
- Protein involved in starch initiation 1
- At3g27230
- Tetratricopeptide repeat
- Uncharacterized protein AT4g35690
- At4g12840
- At4g27620
- MIF4G domain-containing protein
- Pentatricopeptide repeat
Sequence:
MSPLQWLTISFALIIFHSLTVSSSVLSHSDRVTRLPGQPRVGFQQYSGYVTVDDKKQRALFYYFAEAETNPSSKPLVLWLNGGPGCSSLGVGAFSENGPFRPKGPILVKNQHSWNQEANMLYLETPVGVGFSYSTQSSHYEGVNDKITARDNLVFLQRWFLKFPHYLNRSLFITGESYAGHYVPQLAELMIQYNKKHHLFNLRGIAIGNPVLEFATDFNSRAEYFWSHGLISDSTYKMFTSYCNYSRYVSEYYRGSMSSMCSKVMSQVSTETSRFVDKYDVTLDVCIPSVLSQSKVVSPNQVGESVDVCVEDETVNYLNRRDVQEALHARLIGVREWTVCSNVLDYQLLDVEIPTINIVGSLVKAGVPVLVYSGDQDSVIPLTGSRTLVSRLAKQLGLRTSVPYRVWFAGQQVGGWTQVYGNVLSFATVRGASHEVPFSQPERSLVLFKAFLDGHPLPEEF
Protein: Beta-lactamase TEM (EC 3.5.2.6) (IRT-4) (Penicillinase) (TEM-1) (TEM-16/CAZ-7) (TEM-2) (TEM-24/CAZ-6) (TEM-3) (TEM-4) (TEM-5) (TEM-6) (TEM-8/CAZ-2) (P62593)
Organism: Escherichia coli
Function: TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors.
Interaction partners:
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
Protein: Protein HIDE1 (A8MVS5)
Organism: Homo sapiens (Human)
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
Sequence:
MPWTILLFAAGSLAIPAPSIRLVPPYPSSQEDPIHIACMAPGNFPGANFTLYRGGQVVQLLQAPTDQRGVTFNLSGGSSKAPGGPFHCQYGVLGELNQSQLSDLSEPVNVSFPVPTWILVLSLSLAGALFLLAGLVAVALVVRKVKLRNLQKKRDRESCWAQINFDSTDMSFDNSLFTVSAKTMPEEDPATLDDHSGTTATPSNSRTRKRPTSTSSSPETPEFSTFRACQ
Protein: HAPp48,5 protein (Reverse transcriptase-like protein) (P92952)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEEETHDGSLDLQEIRRRVKELDFFPRNCREEPVESCSSDYETLVVQDFVLQFEPKVKEIVEEYGDVDLLDVEDSDAYLEYLRNELQSVEAESAKVSEEIERLSQSHAQDSSRLQRDLEGLLLSLDSMSSQDVEKSKENQPSSSSMEVCEVIDDDKFKMFELENQMEEKRMILKSLEDLDSLRKRFDAAEQVEDALTGLKVLEFDGNFIRLQLRTYIQKLDGFLGQHKFDHITEPSELIHELLIYLKDKTTEITKFEMFPNDIYIGDIIEAADSFRQVRLHSAVLDTRSSVQWVVAKVQDKIISTTLRKYIVMSSKTIRYTFEYYDKDETIVAHIAGGIDAFLKVSDGWPLLNTPLKLASLKNSDNQSKGISLSLICKVEELANSLDLETRQNLSGFMDAIEKILVEQTREELQSNKSSQK
Protein: bZIP transcription factor 68 (AtbZIP68) (Q84LG2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds to the G-box motif (5'-CACGTG-3') and other cis-acting elements with 5'-ACGT-3' core, such as Hex, C-box and as-1 motifs. Possesses high binding affinity to G-box, much lower affinity to Hex and C-box, and little affinity to as-1 element. G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control (Probable). Binds to the G-box motif 5'-CACGTG-3' of LHCB2.4 (At3g27690) promoter. May act as transcriptional activator in light-regulated expression of LHCB2.4. Probably binds DNA as monomer. DNA-binding activity is redox-dependent.
Subcellular location: Nucleus {ECO:0000269|PubMed:18315949}.
Interaction partners:
- G-box-binding factor 4
- Transcription factor MYB3R-5
Sequence:
MGSSEMEKSGKEKEPKTTPPSTSSSAPATVVSQEPSSAVSAGVAVTQDWSGFQAYSPMPPHGYVASSPQPHPYMWGVQHMMPPYGTPPHPYVTMYPPGGMYAHPSLPPGSYPYSPYAMPSPNGMAEASGNTGSVIEGDGKPSDGKEKLPIKRSKGSLGSLNMIIGKNNEAGKNSGASANGACSKSAESGSDGSSDGSDANSQNDSGSRHNGKDGETASESGGSAHGPPRNGSNLPVNQTVAIMPVSATGVPGPPTNLNIGMDYWSGHGNVSGAVPGVVVDGSQSQPWLQVSDEREIKRQRRKQSNRESARRSRLRKQAECDELAQRAEVLNGENSSLRAEINKLKSQYEELLAENSSLKNKFSSAPSLEGGDLDKNEQEPQRSTRQDVA
Protein: Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Protein KE04) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1) (O75477)
Organism: Homo sapiens (Human)
Function: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:11118313, ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:19240031}; Single-pass type II membrane protein {ECO:0000269|PubMed:11118313, ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:19240031}. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
Interaction partners:
- Erlin-2
- Prohibitin 1
- E3 ubiquitin-protein ligase RNF170
- E3 ubiquitin-protein ligase RNF185
- E3 ubiquitin-protein ligase AMFR
- Transitional endoplasmic reticulum ATPase
- Transmembrane and ubiquitin-like domain-containing protein 1
- FAS-associated factor 2
- Ubiquitin-associated domain-containing protein 2
- E3 ubiquitin-protein ligase synoviolin
Sequence:
MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG
Protein: tRNA (guanine(37)-N(1))-methyltransferase Trm5b (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (Q9V0Q0)
Organism: Pyrococcus abyssi (strain GE5 / Orsay)
Function: Specifically methylates the N1 position of guanosine-37 in various tRNAs.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
Sequence:
MTLAVKVPLKEGEIVRRRLIELGALDNTYKIKREGNFLLIPVKFPVKGFEVVEAELEQVSRRPNSYREIVNVPQELRRFLPTSFDIIGNIAIIEIPEELKGYAKEIGRAIVEVHKNVKAVYMKGSKIEGEYRTRELIHIAGENITETIHRENGIRLKLDVAKVYFSPRLATERMRVFKMAQEGEVVFDMFAGVGPFSILLAKKAELVFACDINPWAIKYLEENIKLNKVNNVVPILGDSREIEVKADRIIMNLPKYAHEFLEHAISCINDGGVIHYYGFGPEGDPYGWHLERIRELANKFGVKVEVLGKRVIRNYAPRQYNIAIDFRVSF
Protein: Always early (Q2PNP1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRHQLKKPRKMVAAWQNDELFIKRPNFAPRIRISEKPEIQGRIKPGVASKRTENFTKKPSNISVDVSEDEKAKEKEKEQDPYSNDFILGKRLYNFLKYLSSHRWIWCEFVDSFLDKPTLTMGYDMKRFIAEYCPLLHSCFMPRRGWQLVRRNMGKARRFSAAFIELEREELECQRRIVRQLQQHKFNPKENVGYLDQIPKRVPLPLAKDATVSSFLHGKSFEGIVNGTVMGYDPQDYTYLVRFNRNDNAVVLSLPDSQLYSDEETAAVPLSIIMRGNKSSSVISESAKTEKFGNKRYTKELLESMLRVGKLQDVKHKILMDLARMNEDFETFKEIGSSSSRRDAKVTPQRENLQRRYSASMITLHRVNADILEPLRILHDYLVEYQKQDEEEESKRGRPASEVYQKCRMQAEQDLKTAADEKFLKIESDRTQEFVRNLHTILYLNGKLGRENSSNLETIIADLVTHMVDNIQPSLGRKLKDGVDSLEPLRQQVVQIFKDVKKPERFQITQQAPMQTEDGIYNFVVEAQPDTPS
Protein: Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2) (Q9JJF9)
Organism: Mus musculus (Mouse)
Function: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD). Essential for degradation of the invariant chain CD74 that plays a central role in the function of antigen-presenting cells in the immune system. Plays a role in the regulation of innate and adaptive immunity.
Subcellular location: Late endosome membrane {ECO:0000269|PubMed:21896273}; Multi-pass membrane protein {ECO:0000305}. Lysosome membrane {ECO:0000269|PubMed:21896273}; Multi-pass membrane protein {ECO:0000305}. Membrane {ECO:0000250|UniProtKB:Q8TCT8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8TCT8}; Lumenal side {ECO:0000250|UniProtKB:Q8TCT8}. Note=Colocalizes with palmitoylated and myristoylated proteins at the plasma membrane. {ECO:0000250}.
Interaction partners:
- Tumor necrosis factor
Sequence:
MGLLHSLHAPAAALLWSCLLGLAAAQEAILHASTNGVSSLSKDYCMYYNNNWTRLPSSLENATSLSLMNLTGTALCHLSDIPPDGIRNKAVVVHWGPCHFLEKARIAQEGGAAALLIANNSVLIPSSRNKSTFQNVTVLIAVITQKDFKDMKETLGDDITVKMYSPSWPNFDYTLVVIFVIAVFTVALGGYWSGLIELENMKSVEDAEDRETRKKKDDYLTFSPLTVVVFVVICCIMIVLLYFFYRWLVYVMIAIFCIASSMSLYNCLSALIHRMPCGQCTILCCGKNIKVSLIFLSGLCISVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTMKLPNFMSCVILLGLLLIYDVFFVFITPFITKNGESIMVELAAGPFENAEKLPVVIRVPKLMGYSVMSVCSVPVSVLGFGDIIVPGLLIAYCRRFDVQTGSSIYYISSTIAYAVGMIITFVVLMVMKTGQPALLYLVPCTLITVSVVAWSRKEMKKFWKGSSYQVMDHLDYSTNEENPVTTDEQIVQQ
Protein: Secretogranin-2 (Chromogranin-C) (Secretogranin II) (SgII) [Cleaved into: Secretoneurin (SN); Manserin] (P13521)
Organism: Homo sapiens (Human)
Function: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
Subcellular location: Secreted. Note=Neuroendocrine and endocrine secretory granules.
Interaction partners:
- Secretogranin-1
- Chromogranin-A
- Secretogranin-3
- Neuroendocrine protein 7B2
- Carboxypeptidase E
- Neurosecretory protein VGF]
- ProSAAS
Sequence:
MAEAKTHWLGAALSLIPLIFLISGAEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQAENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPLDSQSIYQLIEISRNLQIPPEDLIEMLKTGEKPNGSVEPERELDLPVDLDDISEADLDHPDLFQNRMLSKSGYPKTPGRAGTEALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPKAAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM
Protein: Biotin--acetyl-CoA-carboxylase ligase, putative (EC 6.3.4.15) (Q383S3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 3-methylcrotonyl-CoA carboxylase, putative
- methylcrotonoyl-CoA carboxylase
- Acetyl-CoA carboxylase, putative
- ATP-grasp domain-containing protein
Sequence:
MSAFLTPKIHLVGDVSSTMDVVREMLAASPSDTEPFAVLAESQSSGRGTTGRQWSSPRGNMYFSLCLPTTLVAAEFLPVLPLATGLACRAAIMELVEGAVVHVKWPNDIIYDGKKIGGSIAECEGEHLIVGIGINIEVAPPVPDGGRPSYAVNSIASVLGKGAVTPQLLAEAVWRNFFSAVADQGFKRPELIKQFEAAMDKSLVLHKRTPTGRDPMPLHALKLNEWGHLVVGRPDGSEEVLVAEYLF
Protein: Fibroblast growth factor 17 (FGF-17) (Fibroblast growth factor 17b) (FGF-17b) (Q6SJP8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in dorsal-ventral embryonic patterning, by promoting expression of bone morphogenetic protein (BMP) antagonists such as chd. Also involved in anterior-posterior neural patterning and in mesoderm induction.
Subcellular location: Secreted {ECO:0000250|UniProtKB:O60258}.
Interaction partners:
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor 1-A
- Fibroblast growth factor 3
- Fibroblast growth factor receptor 3
- Fibroblast growth factor 23
- Platelet-derived growth factor receptor, beta polypeptide
- Fibroblast growth factor receptor.
- Platelet-derived growth factor receptor alpha
- Fibronectin leucine-rich transmembrane 3
Sequence:
MYGINQRYLYISFHFFVVWCHAQGEKNHPSPNFKQYVREQGSLTDQLSRRQVRVYQLYSRTSGKHVQIRGHRVSATADDGNSYARLYVETDTFGSRVRIKGAESGRYLCMNRRGKLVGKPNGRGRDCIFTEIVLENNYTALENARHEGWFVAFTRKGRPIRASKTRQNQREVHFIKRLHKGPQPFPNAEQPKHFEFISFPSTRRAKRNRKHQTAS
Protein: Protein BROTHER of FT and TFL 1 (Q9FIT4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May form complexes with phosphorylated ligands by interfering with kinases and their effectors.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- UPF0235 protein At5g63440
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein mL46
- At1g64880
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein uL23m
- Large ribosomal subunit protein bL34m
- Large ribosomal subunit protein uL5c
- 50S ribosomal protein L33
- Translation elongation factor EF1B/ribosomal protein S6 family protein
Sequence:
MSREIEPLIVGRVIGDVLEMFNPSVTMRVTFNSNTIVSNGHELAPSLLLSKPRVEIGGQDLRSFFTLIMMDPDAPSPSNPYMREYLHWMVTDIPGTTDASFGREIVRYETPKPVAGIHRYVFALFKQRGRQAVKAAPETRECFNTNAFSSYFGLSQPVAAVYFNAQRETAPRRRPSY
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (F4J8A5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGRSSSKKKKKRGGSGRRGQLKDHGSNADEDNELLSEEITALNCVNVGIMGFDRSDVTGKNNSNYFSAIFQEDCKVVSDSRSPPQIAIKLRPYSKDMGYEDTDISAMLIVRCLPGYPYKCPKLQITPEQGLTTADAEKLLSLLEDQANSNAREGRVMIFNLVEAAQEFLSEIIPESHDEESVPCLTAHRSTQFIEQPMLSNIAKSCSGGPFVYGFIDLFSGLEDARNWSLTPDENRGIVSSVQSHPLDTSRILHQKPDKNLKRFEDHAKEEVALPAPIAKLNTVQEENVDDTSISSFDSSKSTDDVESGLFQNEKKESNLQDDTAEDDSTNSESESLGSWSSDSLAQDQVPQISKKDLLMVHLLRVACTSRGPLADALPQITDELHELGILSEEVLDLASKSSPDFNRTFEHAFNQNMASTSVPQFWEPPSDSCEPNASLPSSRYLNDFEELKPLGQGGFGHVVLCKNKLDGRQYAVKKIRLKDKEIPVNSRIVREVATLSRLQHQHVVRYYQAWFETGVVDPFAGANWGSKTAGSSMFSYSGAVSTEIPEQDNNLESTYLYIQMEYCPRTLRQVFESYNHFDKDFAWHLIRQIVEGLAHIHGQGIIHRDFTPNNIFFDARNDIKIGDFGLAKFLKLEQLDQDGGFSTDVAGSGVDSTGQAGTYFYTAPEIEQDWPKIDEKADMYSLGVVFFELWHPFGTAMERHVILTNLKLKGELPLKWVNEFPEQASLLRRLMSPSPSDRPSATELLKHAFPPRMESELLDNILRIMQTSEDSSVYDRVVSVIFDEEVLEMKSHQSSRSRLCADDSYIQYTEINTELRDYVVEITKEVFRQHCAKHLEVIPMRLLSDCPQFSRKTVKLLTNGGDMLELCYELRLPFVHWISVNQKSSFKRYEISHVYRRAIGHSPPNPCLQADFDIVGGTLSLTEAEVLKVIVDITTHIFHRGSCDIHLNHGDLLDAIWSWAGIKAEHRRKVAELLSMMGSLRPQSSERKLKWVFIRRQLLQELKLPEAVVNRLQTVASRFCGDADQALPRLRGALRADRPTRKALDELSNLLTYLRVWRIEEHVHIDVLMPPTESYHRNLFFQVFLTKENSSGTSNDGVLLAVGGRYDWLVQEVCDREHKMNLPGAVGVSLALETIFQHLPMDLRPIRNEVSTSVLVCSRGGGGLLVQRMELVAELWEKSIKAEFVPTPDPSLTEQYEYANEHEIKCLVIITESGVAQNQIEFVKVRHLELKKEKVVGREELVKFLLDAMAVQFRNPSVWS
Protein: Nuclear pore complex protein An-Nsp1 (Eurofung) (Q5B4N1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
- Ran-specific GTPase-activating protein 1, putative
- Nuclear pore complex protein An-Nup57
- Uncharacterized protein
- Nuclear pore complex protein An-Nup159
- Nuclear pore complex protein An-Nup170
- GTP-binding nuclear protein
- Nuclear pore complex protein AN-Nup192
- Nuclear pore complex protein An-Nup49
- WD40 repeat protein poxJ
- Protein transport protein sec13
Sequence:
MAFNFGKQNSSGGSNGGLFGSAGTSSNTGSSGGLFGNAGATTGGTSSSPFGAAAASNQGSSIFGAGAGSGSSTPKFSFGGATSSQTPNKPTESPASGSSGTGLFGGASKPGGGLFGAATATPASSGTNTLFGGQPSTTPAGPPPQGGAPAQGQSLFGQQKSGGLFGLKTTSSGSDSTPATSAPSLFGGGQSTGSSLFKTTTQESTPSSTATSGNLFSNLGANKPAESTKPTTTAENTSKSLTSNAPASGTQTPSLFAAPSSGTDAASKNTQTTTSSATPQKPLFSLGGATSSATPSFTPAAAPSGGLFGGLGTSKPAETSTTKPAASTGSLFSKPAETATTQAPSTSAEATTIGTGAKPALTATSGPTTTATAATSGTSGTTTAGGPALGASTAGPPPPAQSRLKNKTMDEIITRWATDLTKYQKEFREQAEKVAEWDRMIVENGSRVQKLYGSTVDAERATQEIERQLASVEGQQDELSSWLDRYEREVDEMMSKQVGPGESLQGPDQERERTYKLAEKLSERLDDMGRDLSSMIEEVNNASSTLSKTNKADEPISQIVRILNSHLSQLQTIDMGTTELQTKVAAAQKAGQSMSARFGHGLSMSGAGSANAADDFYRSYMGRR
Protein: Phyllosphere-induced regulator PhyR (Q0PEV3)
Organism: Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) (Methylobacterium extorquens)
Function: Key regulator for adaptation to epiphytic life (leaf colonizing) of the bacterium. Positively regulates several genes including katE, sodA, hsp20, dps and gloA. However, it is not known whether this regulation is direct or indirect. Also induces several dehydrogenases.
Interaction partners:
- Anti-sigma factor
- RNA polymerase sigma factor
- Blue-light-activated histidine kinase
- Blue-light-activated histidine kinase
- Blue-light-activated histidine kinase
- DNA-directed RNA polymerase subunit omega
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
Sequence:
MSTAQLVVQHLPYLRRYARALTGSQVAGDAYVAATLETLVNEPETLGRSTNVKADLFRVFTRIWNSLSVNGHSDQVQHDLPAEVRLGQITPLPRQAFLLSCLEGFSEEDAGVILDVDVSKVRDLVDEAGRELAADMATEILIIEDEPLIAMDLEALVEGLGHNVIGVARTRTEAVKIASESKRPGLILADIQLADGSSGLDAVNDLLKTFEVPVIFITAYPERFLTGERPEPAFLIAKPFQPANVSAVISQALFFQQSARRREAHNA
Protein: Allergin-1 (Allergy inhibitory receptor 1) (Mast cell antigen 32) (MCA-32) (Mast cell Ag-32) (Mast cell immunoglobulin-like receptor 1) (Q3TB92)
Organism: Mus musculus (Mouse)
Function: Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20526344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20526344}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MGDGDSPMCLSAVSFKGIRCWLDKLLLWALTISITLQNAAVDCTRVENNELPSPNLNSSMNVVRMGQNVSLSCSTKNTSVDITYSLFWGTKYLESKRRRGGAVDFHLRISNANESGPYKCKVNVSNLMKYSQDFNFTMAKDESCPSCRLSLLLPGLLLGILVIVLVLAYLIHLKYKKGKKTQREDQSKGSGDAPAQDELYVNACKTQTEQPQEIHYATPVFKEMAPMEEEGGTDGKADYIYSELTH
Protein: Ankyrin 2 (A0A5F9ZI53)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MTTMLQKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKKDNNE
Protein: LD27216p (TBC1 domain family member 15/17, isoform A) (TBC1 domain family member 15/17, isoform B) (TBC1 domain family member 15/17, isoform C) (Q9VPL5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Mitochondrial fission 1 protein
- Ras-related protein Rab7
- Autophagy-related 8b, isoform A
- Autophagy-related 8a, isoform A
- GTPase activating protein and centrosome-associated, isoform B
- GH16847p
Sequence:
MDESVRYDRCHQVQLGVFNESQLSSVEEDVQNLPQQGTGNILFTHDGVLLKKASAEHIADLNTSGSLSLVEYSRSIAEMPRRRLLLEWQPNDSIMIADDSQDQGDWALVDRISGRTRTTSECRAFNTRPIEPSGGATTRSRVMRAQLEDLSSVEVRHRGQTIRFMRKGANGVHSEFFFQHGNADLFVRSMRDQHLIENAETSRSGGEVYAILTTENQKLKKTFAELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSIIGEPLLPAAAGEEIDGGMVDEEPTYSDDGFDELVKELTPEEKVRQQALLEEACERSLFLQFH
Protein: AT5G64130 protein (cAMP-regulated phosphoprotein 19-related protein) (A8MS32)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSSAEDVKEQGNLTNEAEKSMPSSQQEEAVVKKKYGGLMPKKPPLISKVSEVTGLIRDFGVSFLVFLRCVYNQDHERAYFDSADWALGKQGVAKPKGPLEALRPKLQPTQQQTRYRKSPCAPSEGGEDGGAAQAEGGSGN
Protein: ABC-type glutathione-S-conjugate transporter (EC 7.6.2.3) (Q7KTC8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Vacuole membrane {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004128}.
Interaction partners:
Sequence:
MADDTSSPMDRFCGSTFWNATETWYTNDPDFTPCFEQTALVWTPCAFYWAFVIFDFYYLKASLDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELPLYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFADGMPRQTKYQRGENEIPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWNQNVRKNYKNKARVEPKAQFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLTSEANQLSVEKVLVSIALFDLMKLPLTILPMLSVDIAETQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWGDEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFIIQHLQEGNEEEEELNQIKRQISSTADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGGSLRRRTKRQDSHDSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWANDQNVANDTGLRDMYLGVYGAFGFGQVTSYFFCSLTLALGCIFCSKVLHETLLSYVFRWPMELFDTTPLGRVVNRFSKDVDTIDNVLPMLWRMVISQAFAVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQTNPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANLV