wanglab/gogpt-training-data huggingface dataset:
Protein: Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (mSur-2) (Q80YQ2)
Organism: Mus musculus (Mouse)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (By similarity). Also required for transcriptional activation subsequent to the assembly of the pre-initiation complex. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 12
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 15
- Mediator of RNA polymerase II transcription subunit 1
- Mediator of RNA polymerase II transcription subunit 24
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 28
- Mediator of RNA polymerase II transcription subunit 19
Sequence:
METQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLAAFRQFWSGLSQESHEQCVQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDSLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKAILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNGDSTLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRVPLPGTSCLASASVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSHRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTDENEIITQFSVQGFPPLFLCLLWKMLLETDHISQIGYKVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQSDWHTKHMSYHKKYPEKLYFEGLAEQVDPPVPIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMCLRNRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKHAMNAREDNPWVPEDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVNVISSSSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEALLPVVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAVPPQALNSGSPAPQSNQVPASLPVTQ
Protein: Putative delta-6 fatty acyl desaturase (Q9DEX6)
Organism: Cyprinus carpio (Common carp)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGGGGQQTDRITGTNGRFGTYTWEEVQKHTKFGDQWIEVERKVYNVSQWVKRHPGGVRILGHYAGEDATEAFTAFHPDLPLVRKYMKPLLIGELEASEPSQDRQKNAALVEDFRALRERLEAEGCFKTQPLFLILHLSHILLLEAIALMMVWYLGTGWINTAIVAVLLATAQSQAEWLQHDFGHLSVFKTSRWNHLVHKFVVGHIKGASAGRWNHRHFQHHAKPNVFKKDPDVNMLNAFVAGKVQPVEYGVKKIKHLPYNHQHKYFFFIGPPLLIPVYFQFQIFHNMIAHGLWVDLAWCISYYVRYFLCYTQYYGVFWAVILFNFVRFLKSHWFVWVTQMSHIPMQIDYEKHQDRLSMQLVATCNIEQSSFNDWFSGHLNFQIEHHLFPTMPRHNYWRAAPHVRELCAKYGIKYQEKTLQGAFADVVRSLEKSGEIWLDAYLNE
Protein: Secretory carrier-associated membrane protein (Secretory carrier membrane protein) (A0A8I6GL39)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363122}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363122}.
Interaction partners:
Sequence:
MSAFDTNPFADPVDVNPFQDPSVTQLTSAPQSGLAEFNPFSETNAATTVPVTQLPGPSQPAVLQPSVEPAQPSPQLLLRQASKFLPARFLAAGEPSERQMLLGGDSSPRDSYMCKLPKAVAAAAQAGLLRQQEELDRKAAELERKERELQNTAANLHVRENNWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFTSDAANGTAFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYFIQLIGLPNLGTSGWLAALSTVNKGPLAVTIIMMVVAGFFTLCAGLSLFLLQRVHAFYRRTGASFQQAQEEFSQGIFSSRTFRTAASSAARGTFQGN
Protein: Eukaryotic translation initiation factor 6 (eIF-6) (Q38B73)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03132}. Nucleus, nucleolus {ECO:0000256|HAMAP-Rule:MF_03132}. Note=Shuttles between cytoplasm and nucleus/nucleolus. {ECO:0000256|HAMAP-Rule:MF_03132}.
Interaction partners:
- 60S ribosomal protein L19, putative
- Uncharacterized protein
- 60S ribosomal protein L39, putative
- 60S ribosomal protein L5, putative
- 60S ribosomal protein L7a
- 60S ribosomal protein L18a
- 60S ribosomal protein L4
- 60S ribosomal protein L35, putative
- 60S ribosomal protein L10, putative
- 60S ribosomal protein L6, putative
Sequence:
MTLRTRFESSDDVGVFARLTNAYCLVAAGASQNFYSVFEQELASHIPVVYTSIGGSRVVGRLTIGNRHGLVVPSITTDQELQHLRNSLPDSVKVQMVEERLSALGNCVVCNDHVALIHTDLSRETEEVIRDTLQVQTFRTSIAENALVGSYAAVTNKGCMVHPKTPAQDMDEIASLLQVPVVAGTINRGNAAIGSGLVVNDWAAFCGLNTTATEITVVERIFQLRRDLGGDESNLLQQLRDTLVDELA
Protein: LIM domain 7 (A0A8I6AAI2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MKNDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRLKNVLITLYWLGRKAQNNPYYHGPYLNLKAFETLLGQALTKALEDSSCLKRSGRDSGYGDIWCPDRGDFPAPPGSHRREDSFESLDSLGSRSLTSCSSDLTLRGGREGCESDNDWEFTFKMQDYNKDDMSYRRISAIEPKSALPFNRFLPNKSKQPSYVPAPLRKKRPDKNEDNRRSWASPVYTETEGTFSSTQRRAWGPKMENWHTVQETSTSSWCLEEEEEKVTRLPNVVKDDLYVRKLSPVMPSPGSSFDQFLPKGWTPEDMNWKKIKRETYKPWYKEFQGLSQFLLLQALQTYSDDILSSETNVKLDPTSGPRLITRRKNFSPTPGYRAHDLEPQSLDPDLENDDFFVRKTRAFHANPCVLRAFEDFRRFSEPDDAVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSGAPDRYQPVPFPEPWTLPPEIQAKFLSVLERTCPPKDKPSSCRVLVPSHRLKKDDMLTRKIQSWKLGTAVPPISFRPGPCSEADLRKWEAIREASRLRHRKRLMVERLFQKIYGENGSKSLSDVSAEDVQSLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSDRSSKTFREMLQDRESQSSTTTSRRRIYSSDDILDDGVLPPTVTLSETSYQSERLEDKARAHPAEMPKEDSTTFASREDGIAAEIPLASHIPEERRQAPWPSAETRQASSSSAESHQASLPSTESDQARLPSAEPHQASFSSAEPRQVPLVSAEPHQASSFSSTEPHQASLSSALQRPSSLSSSQQSWSTRGESTRISASLPRSYQRSDTARLTSVVTARPFGTSSRGISSLPRSYTMDDGWKYNGDVEVVKREQHDSGRAAGMKPDSSHFILGSSSEKEVATGEDVASLSSFVLPSSSSLSHDQAASSKATFSSTSGLDSVSDSGEGRSSSLREVSRSPDQFSDMRISINQTPGTKHDFGFTIKWDVSGISVASVEKGSPAEFSQLQVDDEILAINNTKFSYKDTKKWEEAMANAQETGNLVMDVRRYGKSGSPETKWIDTTSGIYSTEKSSSLSVTTDFSESLQSPYSESKEINGIHEESNAFDSKGPPGFSYSSWVYLCGSSDSVAPDLPVPTLSAPSRWAWDQEEERRRQERWQKEQDRLLQEKYQREQEKLREEWQRAQQEAERENSKYLDEELMVLNSNSISLTSRESVTASWEPSWSEGSKSLDREGTRAGDEDRGQLEDDAVYEDQSQKLQERLMLEHEKKRKEQEAQEEELRKQREAEAQARAEAEAQARAEAQARAEAQAQAEAEARKRAEAQKLQAERERETSVKIYQYRRPIDSYDLPKREEESSGLLPIDRSKSRSTTELNDPLIEKSGSSKYSDRIGTTSFSQRSSKKDQGPSEAELERQQILQEMRKKTSLHNDNSWIRQRSASVNKEPICLTGIMRRGESLDNLDSQRPGSWRQSSWHSQPAGVYASSSVQDFSRLPPQLLSTSNRAYMRNPSSAVPPLAGSVKTSPGSPSPRSHSPSMSQSGSQLRNRSVSGKRVCSYCNSILGKGAAMIIETLGLCYHLHCFKCVSCERDLGGSSSGAEVRIRNHQLYCNDCYLRFKSGRPTAM
Protein: Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) (Q9BV20)
Organism: Homo sapiens (Human)
Function: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cell projection {ECO:0000269|PubMed:19620624}. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Interaction partners:
- Methylthioribulose-1-phosphate dehydratase
- S-methyl-5'-thioadenosine phosphorylase
- Enolase-phosphatase E1
- Acireductone dioxygenase-requiring))
- Cell cycle regulator of non-homologous end joining
- Purine nucleoside phosphorylase
- Acyl-CoA dehydrogenase family member 10
- Acyl-CoA dehydrogenase family member 11
- Gamma-adducin
- Beta-adducin
Sequence:
MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTLDGPQM
Protein: Peptidase S1 domain-containing protein (Q9VEN0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSLARFLFYILVFSSLYCDLLALEHFIVGGQNAAEGDAPYQVSLQTLLGSHLCGGAIISDRWIITAGHCVKGYPTSRLQVATGTIRYAEPGAVYYPDAIYLHCNYDSPKYQNDIGLLHLNESITFNALTQAVELPTSPFPRGASELVFTGWGSQSAAGSLPSQLQRVQQQHLNSPACESMMSAYEDLELGPCHICAYRQANIGACHGDSGGPLVHQGTLVGILNFFVPCAQGVPDIFMNIMYYRDWMRQTMSGNGKCAQVNQQTIDG
Protein: Regulatory protein zeste (A0A0B4KGD0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- TAR DNA-binding protein 43
- Superoxide dismutase
- Charged multivesicular body protein 2b
- 116 kDa U5 small nuclear ribonucleoprotein component
- ATP synthase subunit gamma, mitochondrial
- Heterogeneous nuclear ribonucleoprotein A1
- Pre-mRNA-processing factor 6
- Cell division cycle 5, isoform A
- ATP synthase subunit alpha, mitochondrial
- TAR DNA-binding protein 43
Sequence:
MLNYWEGQSGASNSTVRVNKQYSATDLEAFMKIAANWQNSNHNLLEGVDIKTEMTQYMNSPSMNMYKKRERTQNWNHQEKKYLLDLCRKDMRIIENKRLDAGLTAVKNKAWKIIHQKFSNQFGTDRTCNRLKEQWRRMKACTRNEILDYNNRLARFGAEVADRKKPSPFTFEVWDFMQEAKKACKSEALDGIDYSKIPLALEEGFEYREDYKFNPEDHDMDDSRTPPQELCDVDIKEEENNETFNETFNHHHLNQSDILGSGERLSVSPNHSISRNGIHEAESPATISTSNVLDSSGAYMAGGGDMSGFQANFNMNNISATLEALNALRSGQFPSAAAAAAAAIHQHQAQAQVAMHHQHNNNNNNNNNNEDDEDSMKPQSKRQRTSSGSMLGSEDQAPVLAPSVPASSDSQALERSGSSNGLTMPGTAVSTNANSSSSNNNNFELRMFMEMQSKEHMMRMKILEVQLQAAKHSRDLVEINKTLALQKLQLELASKRLPS
Protein: V(D)J recombination-activating protein 2 (Q6W9A2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
LFGGRSYMPSTQRTTEKWNSVADCLPHVFLVDFEFGCATSYILPELQDGLSFHVSIARNDTIYILGGHSLASNIRPANLYRIRVDLPLGTPAVNCTVLPGGISVSSAIVTQTNNDEFVIVGGYQLENQKRMVCSIVSLGDNRIEISEMETPDWTPDIKHSKIWFGSNMGNGTVFLGIPGDNKQAMSEAFYFYMLRCSEDNSSEEQKIVSNSQTSTEDAGDSTPFEDSEEFCFSAEAISFDGDDEFDTYNEDDEDDESVTGYWITCSPTCDVDINTWVPFYSTELNKPAMIYCSHGDGHWVHAQCMDL
Protein: Gustatory receptor for sugar taste 61a (Q9W0M2)
Organism: Drosophila melanogaster (Fruit fly)
Function: One of the few identified sugar gustatory receptors identified so far with glucose being its primary ligand and which mediates acceptance behavior.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Gustatory receptor for sugar taste 43a
- Gustatory receptor for bitter taste 66a
Sequence:
MSRTSDDIRKHLKVRRQKQRAILAMRWRCAQGGLEFEQLDTFYGAIRPYLCVAQFFGIMPLSNIRSRDPQDVKFKVRSIGLAVTGLFLLLGGMKTLVGANILFTEGLNAKNIVGLVFLIVGMVNWLNFVGFARSWSHIMLPWSSVDILMLFPPYKRGKRSLRSKVNVLALSVVVLAVGDHMLYYASGYCSYSMHILQCHTNHSRITFGLYLEKEFSDIMFIMPFNIFSMCYGFWLNGAFTFLWNFMDIFIVMTSIGLAQRFQQFAARVGALEGRHVPEALWYDIRRDHIRLCELASLVEASMSNIVFVSCANNVYVICNQALAIFTKLRHPINYVYFWYSLIFLLARTSLVFMTASKIHDASLLPLRSLYLVPSDGWTQEVQRFADQLTSEFVGLSGYRLFCLTRKSLFGMLATLVTYELMLLQIDAKSHKGLRCA
Protein: Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4) (P62345)
Organism: Plasmodium berghei (strain Anka)
Function: Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase. Plays a central role in the host erythrocytes and hepatocytes infection cycles, sexual reproduction and mosquito transmission of the parasite. During the liver stage, involved in sporozoite motility and thus in sporozoite invasion of host hepatocytes, probably together with CDPK1 and CDPK5. Involved in merosome egress from host hepatocytes, probably together with CDPK5. During the asexual blood stage, involved in merozoite invasion of host erythrocytes and motility by stabilizing the inner membrane complex, a structure below the plasma membrane which acts as an anchor for the glidosome, an acto-myosin motor. Required for cell cycle progression in the male gametocyte. During male gametogenesis in the mosquito gut, required to initiate the first round of DNA replication, probably by facilitating the assembly of the pre-replicative MCM complex, to assemble the first mitotic spindle and, at the end of gametogenesis, to initiate axoneme motility, cytokinesis and subsequent exflagellation. For each of these steps, may phosphorylate SOC1, SOC2 and SOC3, respectively. Together with CDPK1, regulates ookinete gliding in the mosquito host midgut.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:30315162}.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:28481199}. Membrane {ECO:0000269|PubMed:28481199}; Lipid-anchor {ECO:0000269|PubMed:28481199}. Chromosome {ECO:0000269|PubMed:28481199}. Note=A small fraction of the protein localizes to membranes and to chromatin. {ECO:0000269|PubMed:28481199}.
Interaction partners:
Sequence:
MGQEMSTQSDMQNENQKGNKRNLKGSQGKNGLKERSTSISKEIVKNSFNNSKLRPGMFIQNSNVVFNEQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHGTYDEKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVRISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGDDTTDLDNAAIEVEVDQILSSIDLDQNGYIEYSEFLTVAIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLFGLGDVSSDCWKTVLKEVDQNNDGEIDFKEFRDMLIKLCNY
Protein: Zgc:158722 (von Hippel-Lindau disease tumor suppressor) (A1L296)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MPQDSQEGQQPLPLVRSLISRIQVNVLFCNCSPRVVKPVWINFLGEPQPYVNIQPYTGRRITTFVGHPWMFRDAETDDPMVVNNKEMYLPASLENGQVANAKITLPVLTLRDRCLQVVRRLVRREDVGRLEIARCLQEDLAQRPSIQADLRRISQRVEQKLLENRELQNRRKHQH
Protein: Cytospin-A (SPECC1-like protein) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (Q2KN98)
Organism: Mus musculus (Mouse)
Function: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21703590}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cell junction, gap junction {ECO:0000250}. Note=Colocalizes with beta-tubulin, acetylated alpha-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center (By similarity). {ECO:0000250}.
Interaction partners:
- Actin, cytoplasmic 2
- Mitogen-activated protein kinase kinase kinase 1
- Myosin XVIIIb
- Unconventional myosin-If
- F-actin-uncapping protein LRRC16A
- Thymosin beta 15b like
- Actin-related protein 2/3 complex subunit 2
- Myosin-IIIa
- Tropomodulin-3
- Ras-related C3 botulinum toxin substrate 3
Sequence:
MKKANRSAGSVPKVSGISKPQTVEKSKPENSSSAPTGVKPVRPGAAAALSKTKSNDDLLAGMAGGVNVTNGIKAKKSTCSSAAPSAPAPAMTISENKSKISTGTSSSAKRSTSAGNKESSSTRERLRERTRLNQSKKLPSVSQGANDVALAKRSRSRTAAEGDIRMSKSKSDNQISDKAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGISEDHCEGEDRSEVKETIIAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGVPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFGRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDTIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSELEEKDTERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNAAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRSNYGELPVQEHLLRTSSTSRPASLPRVPAMESAKTISVSRRSSEEMKRDISASEGASPASLMAMGTTSPQLSLSSSPTASVTPSTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKKRNFTLAFQAAESVGIKSTLDINEMARTERPDWQNVMLYVTAIYKYFET
Protein: Hydroxyacylglutathione hydrolase-like protein (EC 3.1.2.-) (Q6PII5)
Organism: Homo sapiens (Human)
Function: Hydrolase acting on ester bonds.
Interaction partners:
Sequence:
MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHARGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAELGTLPPETKVFCGHEHTLSNLEFAQKVEPCNDHVRAKLSWAKARPLSRRGKRVGGEGTGFGVGGALRQGLMVTGACGHSRRGMRMTCPLCRRLWARSASTTPSCGWREYGCCPGASTVTWTLRKASGDCVLG
Protein: PLAC domain-containing protein (Q8C4U4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
SCIPDCEPGTYFDSELVKCGECHHTCRTCVGPSREECIHCAKSFHFQDWKCVPACGEGFYPEEMPGLPHKVCRRCEENCLSCEGSSRNCSRCKAGFTQLGTSCITNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTCLLAG
Protein: At4g10300 (RmlC-like cupins superfamily protein) (Q9SV91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Aluminum induced protein with YGL and LRDR motifs
- Glycine--tRNA ligase, chloroplastic/mitochondrial 2
- At2g45180
- Probable steroid-binding protein 3
- Major latex protein, putative
- AT3g15450/MJK13_11
- Cytochrome P450 71B38
- Isoleucine--tRNA ligase, cytoplasmic
- Acyl carrier protein 4
- Large ribosomal subunit protein uL4c
Sequence:
MGCIGVVNVTSINPYLTRRSNKPYNSRRPSSMAAAIRAESTEKLGITIEKNPPESKLTQLGVRSWPKWGCPPSKFPWTYSAKETCYLLQGKVKVYPNGSDEGVEIEAGDFVVFPKGMSCTWDVSVAVDKHYQFE
Protein: Cytoplasmic dynein 1 intermediate chain (DH IC) (Dynein intermediate chain, cytosolic) (P54703)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chain mediates the binding of dynein to dynactin.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Dynein light chain, cytoplasmic
- Dynein light chain roadblock
- Dynein light chain Tctex-type
- Dynein heavy chain, cytoplasmic
- Cytoplasmic dynein 1 light intermediate chain 1
- Tubulin alpha chain
- Tubulin beta chain
- Tubulin alpha chain
- Dynactin subunit 2
- Dynactin 150 kDa subunit
Sequence:
MDRDQKKKELEQTKNEMRRKLEEYKERNRIMASKTTPTATTTSTLNTASTPSPPVAQEDFNSIMNSIDSMVPTQATPSSSSTISTSTHAESQKSNYIRPTLTIQSLVIEHDFPPKEIPMYSKGTQTMTDADTSNTNNTPELEAPNKNKTKYQLLQQQQQQQQQQQSSLNQDMQNLSIGTDSINGDGSSTSVANSANIDDDDKDEIEIPELDENEKKDILESDSFKSFFGRSSRVIERALCLDDSIDILVDYTISDENSKGTSKELKLLATLSDERWTKHRSITDISWSTKHPELVVSSYSANEAGSHDPDGVALVWSVNNYFQKPEYVFTCQSPVMTTFFSKFHSTLIVGGTYSGQIVIWDTRAEAKPVQKTPLSSVGHTHPVYSMAVVGSANANSLVSISTDAKLCSWNLENLSQPIETIELNSSNTNSANKAGGGGSGGGAPNMSIAVTSLVFPENELNHFYIGTEEGVICQAGRHGNRIVMNERYKGHFGPITSVDLHPSKGGADFSQYFLSSSTDWTCKLWSSKKETPLYSFEDYVDYVYDARWSPVHPSIFSTGDGSGTLSLWDLNQDLEAPIFRHKISNRSVNRLAWSHDGKRILVGDSGGSLSLFDSSEFSSPTSEEYSQFEDVMTKMVNKSRTSDSPLLGEGENQE
Protein: Putidaredoxin reductase CamA (Pdr) (EC 1.18.1.5) (Putidaredoxin--NAD(+) reductase) (P16640)
Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
Function: The oxidation of camphor by cytochrome P450-CAM CamC requires the participation of the flavoprotein, putidaredoxin reductase CamA, and the iron-sulfur protein, putidaredoxin CamB, to mediate the transfer of electrons from NADH to P450 for oxygen activation.
Interaction partners:
Sequence:
MNANDNVVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATVIPHHLPPLSKAYLAGKATAESLYLRTPDAYAAQNIQLLGGTQVTAINRDRQQVILSDGRALDYDRLVLATGGRPRPLPVASGAVGKANNFRYLRTLEDAECIRRQLIADNRLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRTGTQVCGFEMSTDQQKVTAVLCEDGTRLPADLVIAGIGLIPNCELASAAGLQVDNGIVINEHMQTSDPLIMAVGDCARFHSQLYDRWVRIESVPNALEQARKIAAILCGKVPRDEAAPWFWSDQYEIGLKMVGLSEGYDRIIVRGSLAQPDFSVFYLQGDRVLAVDTVNRPVEFNQSKQIITDRLPVEPNLLGDESVPLKEIIAAAKAELSSA
Protein: Tubulin gamma-2 chain (Gamma-2-tubulin) (P38558)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:P38557}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Note=Present in discrete dots in the cytoplasm and cell cortex. {ECO:0000250}.
Interaction partners:
- Gamma-tubulin complex component 2
- Gamma-tubulin complex component 4
- Gamma-tubulin complex component 3
- Protein NEDD1
- Gamma-tubulin complex component
- Gamma-tubulin complex component
- Spc97 / Spc98 family of spindle pole body
- Spindle pole body component
- AUGMIN subunit 3
- AUGMIN subunit 1
Sequence:
MPREIITLQVGQCGNQIGMEFWKQLCLEHGISKDGILEDFATQGGDRKDVFFYQADDQHYIPRALLIDLEPRVINGIQNGEYRNLYNHENIFLSDHGGGAGNNWASGYHQGKGVEEEIMDMIDREADGSDSLEGFVLCHSIAGGTGSGMGSYLLETLNDRYSKKLVQTYSVFPNQMETSDVVVQPYNSLLTLKRLTLNADCVVVLDNTALNRIAVERLHLTNPTFAQTNSLVSTVMSASTTTLRYPGYMNNDLVGLLASLIPTPRCHFLMTGYTPLTVERQANVIRKTTVLDVMRRLLQTKNIMVSSYARNKEASQAKYISILNIIQGEVDPTQVHESLQRIRERKLVNFIDWGPASIQVALSKKSPYVQTSHRVSGLMLASHTSIRHLFSRCLSQYDKLRKKQAFLDNYRKFPMFADNDLSEFDESRDIIESLVDEYKACESPDYIKWGMEDPGQLMTGEGNASGVADPKLAF
Protein: Trans-2-enoyl-CoA reductase [NADH] (TER) (EC 1.3.1.44) (Q73Q47)
Organism: Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
Function: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of the carbon-carbon double bond of crotonyl-CoA to yield butyryl-CoA. In vitro it can also use hexenoyl-CoA and dodecenoyl-CoA as substrates.
Interaction partners:
- 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
- 3-oxoacyl-[acyl-carrier-protein] synthase 2
- Uncharacterized protein
- Cell filamentation protein Fic
Sequence:
MIVKPMVRNNICLNAHPQGCKKGVEDQIEYTKKRITAEVKAGAKAPKNVLVLGCSNGYGLASRITAAFGYGAATIGVSFEKAGSETKYGTPGWYNNLAFDEAAKREGLYSVTIDGDAFSDEIKAQVIEEAKKKGIKFDLIVYSLASPVRTDPDTGIMHKSVLKPFGKTFTGKTVDPFTGELKEISAEPANDEEAAATVKVMGGEDWERWIKQLSKEGLLEEGCITLAYSYIGPEATQALYRKGTIGKAKEHLEATAHRLNKENPSIRAFVSVNKGLVTRASAVIPVIPLYLASLFKVMKEKGNHEGCIEQITRLYAERLYRKDGTIPVDEENRIRIDDWELEEDVQKAVSALMEKVTGENAESLTDLAGYRHDFLASNGFDVEGINYEAEVERFDRI
Protein: Cadherin domain-containing protein (Q3TZ28)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
EGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAKLTYSILECQIQGMSVFTYVSINSDNGYLYALRSFDYEQIKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRLDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGDRGGGSGEHLRPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGNGSSTCCGRQARARKKKLSKSDIMLVQSANVPSNPAQVPVEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRSTDAEHNPCGAIVTGYSDQQPDIISNGSILSNEVRLKGKKHHLSSPPSESLL