wanglab/gogpt-training-data huggingface dataset:
Protein: phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase (EC 3.1.3.86) (W5UIG7)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
Sequence:
MSSHQPWYHGNITRSMAEDLLSKNAKDGSFLLRDSESIQGAYALCVLYQNCVYTYRILPNEEKKLSVQASEGVPIRFFSVVSELVEAYYKENMGLVTHLQYPVQKEEEPEDEPEQFSLPPQLPPRNFTPIESKECHTEPVKTEQKVSILDTYLQRMQLVDMSHISEEHQKAIQDYFSSAVGLDVEQVHNGNLNLPNLKKLLKTICKSLNSEISRTLPSLEALQKIIDQPMSPGAGRLRGQLSLDASQSVSFRLEQLTKLLYSIEDKAKNTVFESAGYDGGHRKSLIPPVTFEVKSDSLGISNKMFLKVDVESGKVYFKKSKDGPEDKYFVHNKILQLVKSKKMHNKLELVVETEKEKTQRKEFVFNDTKKREGFCQLLQQMKNKHSDKAEPDMISLFVGTWNMGNASPPTNITSWFQSKGQGKTRDDTASQIPHDIYVIGTQEDPLGEKDWIDIVRGTLRDITNISFKQIATQTLWNIRIIVLAKPEHENRISHIFCDSVKTGIANALGNKGAVGVSFMFNDTSFGFVNSHLTSGSEKKIRRNQNYVSILRFLNLGDKKLNPFDITHRFTHLFWLGDLNYRIELPTAEAENIVMKIKQQQYQELLCRDQLTMERADGKVFLYYEEEDITFPPTYRLERDTHERYVYTKAKATGTKYNLPSWCDRVLRKSHPQVHVACHSYGCTCDIMTSDHAPVFATFDVGVTSQFVSKNDPIKESQGAIKFMNCVATLKTKSKTKFFIEYHSSCLEKFVKSSEIYNQESTEGSIKVRFEAHVELTPIISDPEYLLDQHILISITSTDSDESYGETCVALRAAEEAYTEFDVPLTHHGEQTGMLSGGIQLRTSEGKLTEKLYDFIKIGDDSGTGKVKSGDHSNKSLALPTDISNPNYMDVGYKSSSQSGWSYTVSNRQGASSGHMAKDTTTGNTSPKKTTYDHSVCSPTGKLSSPTSEEEQPAEMFDNPLYGSMGKSRCGKDQEMSRKEHLVIPEIFAFPKGSESDPDRAPPVPTPRARSFTCSEGKSQNPSPTPSTSSNHSSNSSLQPQSFSKKPVVPSRSEGGGMMSGKPPLPMKSRPEPQSKPRDYRDSSELPGKMRPHARPCQPLPKDVHPEATPSPKTGRPLK
Protein: BOS complex subunit ncln (Nicalin-1) (Nicastrin-like protein 1) (Q6NZ07)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity). Antagonizes Nodal signaling and subsequent organization of axial structures during mesodermal patterning. Ectopic expression results in cyclopia, due to a defect in mesendoderm patterning.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A0A8I3NGV2}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- BOS complex subunit TMEM147
- BOS complex subunit NOMO1
- Thymus, brain and testes-associated.
- PAT complex subunit CCDC47
- Calcium load-activated calcium channel
- DENN/MADD domain-containing 3a.
- U11/U12 small nuclear ribonucleoprotein 35 kDa protein
- Large ribosomal subunit protein eL19
- Ribosomal protein L4
- DENN/MADD domain-containing 3b.
Sequence:
MFEEAGEVLENMLKVSFPLSLVLFLVLVCPLRAEAAHEFSVYRMQQYDLQGQTYGSRNAILNTEARTVEAEVLSRRCVMMRLADFSYEKYQKALRQSAGAVVIILPHNMSTLPQDIVQQFMELEPELLATETIVPVYFALEDEELLSIYTQTQISSSSQGSSSAAEVLLHTATANGFQMVTSGAQSKAVSDWAITSLEGRLTGSGGEDLPTIVLVAHYDSFGVAPWLSYGADSNGSGVAILLELARLFSRLYSYKRTHAGYNLLFFLSGGGKFNYQGTKRWLEDNLDHTDASLLQDNVAFVLCLDTLGNSDNLHLHVSKPPKEGSPQYTLLKELETVVAHQHPDLKFAMVHKKINLADDTLAWEHERFGIRRLPAFTLSHLESHRSPARHSIMDMRSVSPSLEGAGEATTGPHVDLGKLSRNTKVIAETLARVIYNLTEKGVTGDLEIFTEQMQVQEDQLASLVDWLTAQPRAAQLLDKDSSIINTLEHQLSRYLKDVKRHLVRADKRDPEFVFYDQLKQTMNAYRVKPAIFDLLLAVCIASYLGVLYLAIQNFGLLYGFLRRVTAPRVKQH
Protein: Adenosine deaminase (EC 3.5.4.4) (S-methyl-5'-thioadenosine deaminase) (EC 3.5.4.31) (A0A509ALD0)
Organism: Plasmodium berghei (strain Anka)
Function: Catalyzes the hydrolytic deamination of adenosine to produce inosine. Unlike mammalian adenosine deaminases, also catalyzes the deamination of 5'-methylthioadenosine (MTA), a by-product of polyamine biosynthesis, to produce 5'-methylthioinosine (MTI). Plays an essential role in the purine salvage pathway which allows the parasite to use host cell purines for the synthesis of nucleic acids (Probable).
Interaction partners:
- Inosine-5'-monophosphate dehydrogenase
- Adenylosuccinate synthetase
- GMP synthase
- Bifunctional dihydrofolate reductase-thymidylate synthase
- Hypoxanthine phosphoribosyltransferase
- Lysine decarboxylase-like protein, putative
- CTP synthase
Sequence:
MEIPNEEIKFLKKEDIKNINLNGMNKKERYEIWKKIPKVELHCHLDLTFSGKFFLKWVRKYNLQPNMTDDQVLDHYLFTKEGKSLAEFIRKAISVSDIYRDYDILEDLAKWAVIEKYKEGVVLMEFRYSPTFVSSSHGLDIELIHKAFVKGIKNATEMLNNKIYVALICISDTGHSAASIKHSGDFAIKHKHDFVGFDHGGREIDLKDHKDVYHSVRNHGLHLTVHAGEDATLPNLNTLYTAINILNVERIGHGIRVSESEELIELVKKNNILLEVCPISNLLLNNVKSMDTHPIRKLFDAGVKVSVNSDDPGMFLTDINDNYEKLYIHLNFTLEEFMTMNNWALEKSFVNDDIKSKLKTMYF
Protein: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) (Q9LFN1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable LRR receptor-like serine/threonine-protein kinase At2g28960
- Subtilisin-like protease SBT4.9
- Pentatricopeptide repeat-containing protein At5g06540
- Subtilisin-like protease SBT4.4
- Putative defensin-like protein 3
- General transcription and DNA repair factor IIH subunit TFB2
- Probable serine/threonine-protein kinase PBL7
- Glutathione S-transferase T3
- Glutathione S-transferase T2
- Probable inactive receptor kinase At5g16590
Sequence:
MASSFFLTTVAAAIGFFTLLRKLRFHHDNKEKKSTSLSPSSSPSSLSPSSVPPPSSSCIWTHQVFPSFSGEDVRRDFLSHIQMEFQRMGITPFVDNEIKRGESIGPELLRAIRGSKIAIILLSRNYASSKWCLDELVEIMKCREEYGQTVMAIFYKVDPSDVKNLTGDFGKVFRKTCAGKPKKDIGRWRQAWEKVATVAGYHSINWDNEAAMIKKIATDISNILINSTPSRDFDGLVGMRAHLEKMKPLLCLDTDEVRIIGIWGPPGIGKTTIARVVYNQLSHSFQLSVFMENIKANYTRPTGSDDYSAKLQLQQMFMSQITKQKDIEIPHLGVAQDRLKDKKVLVVLDGVNQSVQLDAMAKEAWWFGPGSRIIITTQDQKLFRAHGINHIYKVDFPPTEEALQIFCMYAFGQNSPKDGFQNLAWKVINLAGNLPLGLRIMGSYFRGMSREEWKKSLPRLESSLDADIQSILKFSYDALDDEDKNLFLHIACFFNGKEIKILEEHLAKKFVEVRQRLNVLAEKSLISFSNWGTIEMHKLLAKLGGEIVRNQSIHEPGQRQFLFDGEEICDVLNGDAAGSKSVIGIDFHYIIEEEFDMNERVFEGMSNLQFLRFDCDHDTLQLSRGLSYLSRKLQLLDWIYFPMTCLPSTVNVEFLIELNLTHSKLDMLWEGVKPLHNLRQMDLSYSVNLKELPDLSTAINLRKLILSNCSSLIKLPSCIGNAINLEDLDLNGCSSLVELPSFGDAINLQKLLLRYCSNLVELPSSIGNAINLRELDLYYCSSLIRLPSSIGNAINLLILDLNGCSNLLELPSSIGNAINLQKLDLRRCAKLLELPSSIGNAINLQNLLLDDCSSLLELPSSIGNATNLVYMNLSNCSNLVELPLSIGNLQKLQELILKGCSKLEDLPININLESLDILVLNDCSMLKRFPEISTNVRALYLCGTAIEEVPLSIRSWPRLDELLMSYFDNLVEFPHVLDIITNLDLSGKEIQEVPPLIKRISRLQTLILKGYRKVVSLPQIPDSLKWIDAEDCESLERLDCSFHNPEITLFFGKCFKLNQEARDLIIQTPTKQAVLPGREVPAYFTHRASGGSLTIKLNERPLPTSMRYKACILLVRIGDYGAHDRDKWLHVAFGVRSTTLGHIIYSGLTEHLYTFEIEEKVTSSELVFEFKVENGNHWKIGECGLRQLS
Protein: Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3) (P14138)
Organism: Homo sapiens (Human)
Function: Endothelins are endothelium-derived vasoconstrictor peptides.
Subcellular location: Secreted.
Interaction partners:
- Endothelin receptor type B
- Endothelin-1 receptor
- Endothelin-1
- Kell blood group glycoprotein
- Endothelin-converting enzyme 1
- Endothelin-2
- Endothelin-converting enzyme 2
- Transcription factor SOX-10
- Glial cell line-derived neurotrophic factor
- EEF1AKMT4-ECE2 readthrough transcript protein
Sequence:
MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
Protein: C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein) (Q7TPS5)
Organism: Mus musculus (Mouse)
Function: Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cell membrane {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation. {ECO:0000250}.
Interaction partners:
- RAC-beta serine/threonine-protein kinase
- Cyclin-dependent kinase 5
Sequence:
MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDSNRFRQSSCGVKFFCTTSIPKCYRAVVIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAAFLPACSSPSRELKEIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKTGMGSGSAGKEGGPFKALLRQQTQSALEQREFPFLTLTAFPPGLLVHVGGVVSARSVKLLDRIHNPDEPETRDAWWAEIRQEIKSHAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQEGTVEGCLEQRIEENLPVGCGFCHIPYDELNMPFPAHLTYCYNCRKQKVPDVLFTTIDLPTDAVVVGKGCLIQARLCRLKKKAQAEANATAISNLLPFMEYEVHTQLMNKLKLKGMNALFGLRIQITVGETMLMGLASATGVYLAALPTPGGIQIAGKTPNDGSYEQHISHMQKRINDTIAKNKELYEITPPEVSEEMIGSPIPEPRQRSRLLRSQSESSDEVTELDLSHGKKDAFVLEIDDTDAMEDVHSLLTDAPPPSGFYSCNTEIMPGINNWTSEIQMFTSVRVVRLSSLNLTNQALNKNFNGLCENLLKSLYFKLRSMTPCCLCHVNFTVSLPEDELIQVTVTAVAITFDKNQALQTTKPHVEKSLQRASTDNEELLQFPLELCSDSLPPHPFPAAKEHLESANSNSGIPAAQRAVTVEKASAMGDGNFRNRSAPPCASPTVGVVKMTPLSFIPGAKITKYLGIINMFFIRETTSLREEGGVSGFLHAFIAEVFAMVRAHVAALGGNAVVSYIMKQCVFMENPSKNQAQCLINVSGDAVVFVRDSDLEVMSSQQPAANCQPSCTGEVTT
Protein: Thyrotropin receptor (Q7T2G8)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Cell membrane {ECO:0000256|RuleBase:RU361222}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361222}.
Interaction partners:
- Gonadotropin subunit beta-1
- Glycoprotein hormones alpha chain
- Glycoprotein hormones alpha chain
- Glycoprotein hormones alpha chain
- Glycoprotein hormones alpha chain
- Thyrotropin subunit beta
- Gonadotropin subunit beta-2
- Thyrotropin subunit beta-like
Sequence:
MMKMKKIMKMLLCVLGCVCVSQAEVAMVNSGTTFTYLCMGNTITHMPTHIPKNTTNLEFKQTHIRVFPREAFTNLLQLTAIVLTENGMLESIGAFAFANLPRLTEITITKSKHLVVIHHQAFMGLPKLSHLTICNTGLRVLPNFSRIHSTALTFLLDLQDNVHIVIIPSNAFLGLTTNTIDELRLTKNGISEVESHAFNGTKIHKLFLMGNLQLSHMHNNSFKGAEGPGFLDISRTALSSLPESVLGEVEHLSAVSVFSLRALPPLSLFTKLRQANLTYPSHCCAFHKHQRNRTFRMNSACFKPGAQDNLHFFMDFCLNWTSVACSPAPDAFNPCEDIMGSAPLRVLIWIISVLALLGNTIVLLVLLGSRAKMTVPRFLMCHLSFADLCMGVYLVVIATVDVRTRGLYYNHAISWQTGAGCDIAGFFTVFASELSVFTLTAITLERCHTITHALRLDRKLRLRHACAVMATGWAFSCLAALLPTVGVSSYSKVSICLPMDVESLPSQVFVMFLLLLNVVAFLCVCVCYLSIYLSVRNSSSPPASAETRMAQRMAILIFTDFLCMAPISFFALSAALKLPLITVSDSKLLLVLFYPINSCANPFLYGLCTRTFRRDFFLLAARYGLFTTKAQIYRTESFSVQQAAWIQMSPKTSHGTLC
Protein: Protocadherin gamma A12 (Q8K4A6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
GDSVFSKDNHALNQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Protein: Small ribosomal subunit protein uS2 (F4J4W3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_03015}.
Interaction partners:
Sequence:
MAANGVATAGRQVSEKEADIQMMLSADVHLGTKNCNYQMERYVFKRRDDGIYIINLGKTWDKLQMAARVIVAIENPKDIIVQSARPYGQRAVLKFAQYTGVNAIAGRHTPGTFTNQMQTSFSEPRLLILTDPRTDHQPIKEGALGNIPTIAFCDTDSPMGFVDIGIPANNKGKHSIGCLFWLLARMVLQMRGTILAAQKWDVMVNSRNTIRTCVSPTPDKDLDLFLLCRWICFSTGSPKKQSKRVMKKLKYRPIMEWLVVTSGPLLKYLMLHGLVKSNSQFLLHLQLALPLLLDGRLLLFQLLVGSKSSLISLARTRLDVDLIFLFSRFGED
Protein: Epoxide hydrolase 2 (E5RFU2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM
Protein: UDP-glucuronosyltransferase (EC 2.4.1.17) (D3XD61)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}. Membrane {ECO:0000256|RuleBase:RU362059}; Single-pass membrane protein {ECO:0000256|RuleBase:RU362059}.
Interaction partners:
Sequence:
MRLGVIFILVVGVVCSAAVDQKPSRKSSWTGKLLVVPMDGSHWTGVKAVAEEMGRRGHTVIVVIPEISVLLGPGQHYITKMFSVKYDQKSLNKVLNERVLEVTNPGNSFLSTVIRIVSNLRRMFNTMAATSESLFQDKELIESLRNENFDAVLTDPVLPMGAILAYNLSVPAVYLLRGMACGLDATATTCPNPSSYIPRFHTRNTDRMSFGERVMNMLMSILEQTVCKFMYRSFEEMIFNFLQRDVSMTEILRTGAVWLMRYDFTLEFPKPLMPNMQFIGGINCGVRNPLTKEVEEFVNGSGEHGIVVFSLGSLVSSMPKEKADIFFKAFSMIPQRVLWRYTGEIPNNVPENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHELNWLQYHSLDVIGFMLLIVLIVTLAMLKCCSLCWRRCCRKTQKRKED
Protein: Homeobox protein ceh-40 (Q19503)
Organism: Caenorhabditis elegans
Function: Plays a role in regulating gene expression in dopaminergic neurons, acting redundantly with homeobox protein ceh-20 in head neurons. May activate dopamine pathway genes in concert with ETS domain-containing protein ast-1, and homeobox proteins ceh-43 and ceh-20.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeobox protein unc-62
- Homeobox protein php-3
- Homeobox protein nob-1
- Homeobox protein ceh-13
- Homeobox protein ceh-43
- Transcriptional coregulator psa-3
- Homeobox protein lin-39
Sequence:
MSEASKSIMDLLSEVVKITDMTMDNEAVNKLKPQIKINPFYRAVQDVLVEQKSKIDLSTKMMKDLEAQENDERLDTMLKAEGVAGPDDSLLRIQEAAGTDQYEYRQQLLKVRRELENETKAFDKHCKKWCEYVEDVLQQQGEFRPITQQSTEKFMNKMSGKFNKVCFVLKQTACEEVIQLKKRYLDARRKRRNFSKTSTEILNEYFLANINHPYPSEEVKQALAMQCNISVAQVSNWFGNKRIRYKKTMAKNEDERRENRKPEDRPPPGAPGAPYSLVPNAFAGMMNPYQMMLPGHQFPIGVAPFNFSMYNPEMMAQYQQSLQNPNQTR
Protein: Ribosomal protein L11 methyltransferase (L11 Mtase) (EC 2.1.1.-) (P0A8T1)
Organism: Escherichia coli (strain K12)
Function: Methylates ribosomal protein L11.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00735, ECO:0000305}.
Interaction partners:
- Sodium/pantothenate symporter
- Uncharacterized membrane protein YhdT
- Ribosomal protein uL3 glutamine methyltransferase
- Ribosomal RNA small subunit methyltransferase E
- DNA-binding protein Fis
- tRNA-dihydrouridine synthase B
- Large ribosomal subunit protein uL11
- Release factor glutamine methyltransferase
- Biotin carboxylase
- Ribosomal RNA small subunit methyltransferase B
Sequence:
MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
Protein: receptor protein serine/threonine kinase (EC 2.7.11.30) (Q288P3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAVEGRITILDVGLIAMVVLLGPVAAAQSEQRECAYAEQPQGLAERIGGRGEGLVFHENSTIRCYQGHRCFGLWGKKNNGVVLVKQGCWTNVGDHQECYDRCVVTNPPSVAQNGTYRFCCCNKDMCNLNFTEDFPPPSPTTAQPLQSRRLHREEVIVVALATVSMVAVLVILLFFGYRMLRGRGSHSLHTLNILETALSPPSLDLDNLTLQELIGRGRYGTVYRASLDDRSVAVKVFISANRQQFTNERMIYRLLLDHENIARFLESEERVGTEGRTEFLLLLEFYPHGSLCTYLSGRTVDWLSCCRLALSVTRGLAYLHTEIQRGDVYKPAVSHRDLNSRNVLVKTDGSCVISDFGLSMILTGKRPPGHGEEDNSAISEVGTVRYMAPEVLEGAVNLRDCESALKQVDVYALGLVYWETFMRCADLFPGETVPAFQLAFQAEVGNHPTIEDMQALVSREKERPKFPEAWKENSLTVHSLKETMEDCWDQDAEARLTAQCAEERLAELLLIWDREKSASPALNHSTALQTPKVGSVLEHSSTNTEDHEGADKPLHNDTSVEQTSAGGTNPAEKKKNCINYEWQQAQSRQSGTESSSATPVSESCNATHPPPVATNLCAQLTREDLEIPKLDPSEVQRNMRESSDESLMEHSQKQFCSPETSASHGPFYPLMKMVSEVSGSQGSSRHGDTPITILPKQQNVPKRPSSLSLHVKPGKTSTSTSSSLRMKFGKLGKSNLKKVEMGVAKSSVVNATHEARLITVANNDAAAAMNKYATEPAAESAGSSANEDLTFGLLNTSPDEQEPLLRREAHPDNANNNNSNNNNGEGDGDGETEGGGEGGENNESVGPTGDASSSSTVEPVVLPGPCSASTAIPPQAQSQTQTHGEALLRQNRVRRPERPNSLDLSITTLPLLGGRSVGDGTEGSGDKIKKRVKTPYALKKWRPASWVITTDTLDAEVNNNSRHGGGLGQNQNQAGTSRPKSASAVYLGSRGGSRFSDPNDCDF
Protein: Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)] (O46600)
Organism: Bos taurus (Bovine)
Function: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P10912}; Single-pass type I membrane protein {ECO:0000255}. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway. {ECO:0000250|UniProtKB:P19941}.; SUBCELLULAR LOCATION: [Growth hormone-binding protein]: Secreted {ECO:0000250|UniProtKB:P10912}. Note=Complexed to a substantial fraction of circulating GH. {ECO:0000250|UniProtKB:P10912}.
Interaction partners:
- Tyrosine-protein kinase
- Somatotropin
- Placental prolactin-related protein 1
- Placental prolactin-related protein 4
- Placental prolactin-related protein 3
- Growth hormone E4
- Prolactin-related protein VIII
- Growth hormone E5
- Prolactin-related protein IX
- Prolactin-related protein 14
Sequence:
MDLWQLLLTLAVAGSSDAFSGSEATPAFLVRASQSLQILYPVLETNSSGNPKFTKCRSPELETFSCHWTDGANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAGENSCYFNSSYTSVWTPYCIKLTSNGGIVDHKCFSVEDIVQPDPPVGLNWTLLNISLTEIHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDPLMVTSVPMYSLRLDKEYEVRVRTRQRNTEKYGKFSEVLLITFPQMNPSACEEDFQFPWFLIIIFGILGLAVTLYLLIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEKSLNIFGAKDDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDAAPASQQPSVILVEENKPRPLLIGGTESTHQAVHTQLSNPSSLANIDFYAQVSDITPAGNVVLSPGQKNKTGNPQCDTHPEVVTPCQANFIVDNAYFCEVDAKKYIALAPHVEAESHVEPSFNQEDIYITTESLTTTAGRSGTAEHVPSSEIPVPDYTSIHIVQSPQGLVLNATALPLPDKEFLSSCGYVSTDQLNKIMP
Protein: Lysine-specific histone demethylase (EC 1.14.99.66) (A0A0P0UQI8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR038051}.
Interaction partners:
Sequence:
MLSNKKSDPGSSSSSGGNGGDRAPETLAAPQAGPAGPSGPISADVKKKERASPSGEPGGPPLPHPPGPGGIDQDSAEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKERKQVIPPPAPPIEEENDSEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIINGPQHTQKVFLYIRNRTLQLWLDNPKVQLTFEATVQQLEAPYNSDAVLVHRIHSYLERHGFINFGIYKRVKPLPTKKTGKVIVIGAGVSGLAAARQLQSFGMDVTVLESRDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAGERCTSVPKEKDEMVEQEFNRLLEATSYLSHQLDFNFLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKDLLNKMVTTKEKVKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELVEMQVKLEERLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTSSGCEVIAVNTRSTTQTFIYKCDAVLCTLPLGVMKQQPPAVQFVPPLPEWKTAAIQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALMAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPAIPGASQPVPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTMPRQATANPNPQPSPSIQ
Protein: Siderophore iron transporter mirC (Major facilitator iron-regulated transporter C) (Q870L3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- GATA-type transcription factor sreA
Sequence:
MPLLEPSATAYGTFGDMRPDTEDEGERLLTDGYVSDDDGSAVTSVDSVQEGVRKIEAINITWTTRSLVIAYISIFLMAFCTSLEGQTIMSLSAYATSAFSKHSLISTVLVVQNVVNAVIKPPMAKIADVFGRFEAFCVSILIYVLGYIQMAASTNVQTYASAQIFYAAGSTGLQILQQVFIADSSSLLNRALLALLPELPFLVTVWIGPTIADVVLENSSWRWGYGMWSIILPASFLPLALSLLLNQRKAKRLNLIKERPHHRRGFVAAVRRTWYDLDIFGLALLSAAVTLILVPLTLAANTKNGWKSNSIVAMIVIGVVCLILLPFWETSKKLAPKPLLSLHLLKQRTALAGCCLAFFYFMAFYFSVQPYLYSYLQVVQGYDVATAGRVTQTFAFTSTIAAFGVSILIKYTRRYRVYVTLGCVIYMTGLLLMLLYRKEGSSPLQVLGTQVIVGMGGGLLNVPVQLGVQASASHQEVAAATAMFLTSMEMGGAVGAAISGAVWTHNIPRKLNLYLPDEYKSEAGAIFGKLTKALSYEMGTPVRSAINRSYQETMNKLLVLALLATLPLIPLSLLMSNYKLDKMSESSDHDDASPRNGLGPGERAKRT
Protein: Core-capsid bridging protein (Core protein V) (P03267)
Organism: Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
Function: Associates loosely with the viral DNA to form an outer shell around the nucleoprotein-DNA complex and links it with the capsid by binding the endosome lysis protein. Dissociates from the viral genome during entry. Might be involved in nuclear capsid assembly of the viral particles through its association with NPM1/nucleophosmin.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04053}. Host nucleus, host nucleolus {ECO:0000255|HAMAP-Rule:MF_04053, ECO:0000269|PubMed:9680130}. Note=Located inside the capsid (core). Present in 157 copies per virion. Localizes in the nucleoli during infection, then translocates from the nucleoli to the nucleoplasm as the infection progresses and is finally incorporated into the viral particles. {ECO:0000255|HAMAP-Rule:MF_04053}.
Interaction partners:
Sequence:
MSKRKIKEEMLQVIAPEIYGPPKKEEQDYKPRKLKRVKKKKKDDDDDELDDEVELLHATAPRRRVQWKGRRVRRVLRPGTTVVFTPGERSTRTYKRVYDEVYGDEDLLEQANERLGEFAYGKRHKDMLALPLDEGNPTPSLKPVTLQQVLPTLAPSEEKRGLKRESGDLAPTVQLMVPKRQRLEDVLEKMTVEPGLEPEVRVRPIKQVAPGLGVQTVDVQIPTTSSTSIATATEGMETQTSPVASAVADAAVQAAAAAASKTSTEVQTDPWMFRVSAPRRPRRSRKYGTASALLPEYALHPSIAPTPGYRGYTYRPRRRATTRRRTTTGTRRRRRRRQPVLAPISVRRVAREGGRTLVLPTARYHPSIV
Protein: Outer dynein arm-docking complex subunit 1 (F1N2N9)
Organism: Bos taurus (Bovine)
Function: Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}.
Interaction partners:
- Outer dynein arm-docking complex subunit 3
- Outer dynein arm-docking complex subunit 2
- Outer dynein arm-docking complex subunit 4
- Calaxin
- Methyl-CpG-binding domain protein 1
- Cilia and flagella associated protein 45.
- Protein Flattop
- Tektin-1
- Coiled-coil domain 40 molecular ruler complex subunit
- Tektin bundle-interacting protein 1
Sequence:
MPFGLSAGSTRSEDGSEAFLEGMVDWELSRLQRQCKVMEDERRAYSKEVHQRINKQLEEIQRLEGVRHKLRVQISIAQSQVRRLRDSERLESMGHLLKCQVRVQAEVKELQAQNQALDREIQEWESRNSAHSKNARSPGCVQHDKVKSQRRIKSLENQLDKVICRFDIQLAQNATLREELDLLRIERNRYLNVDRKLQKEIQLLKDSVRNLMVSSTSAYTVREEAKAKLGMLRERAEKEVAQNETEVQILQRQIAHLEQLHHFLKLKNGDRQPDSAIVEKREQRAREVAEGLRKTSQEKLVLRYEDALNKLSQMTGESDPDLLVEKYLELEERNFAEFNFINEQNSELEHLQEEIKEMQEALVSGRRSEEDRRAQQEQQRAELQQRVDDVHSEADDLEARYHNFREQLEKLKTNIQHLFTRAQCDSTLINDLLGIKTHMRDRDISLFLSLIEKRLVQLLTVQAFLETQVVVMFNAALMVLGQSSEDFPKKVAPPQPPDNLEDPPGFEAKDDYPLSKEELLSSVMKAEQHLKELVESIKVESTPSMTSSTQKVSSSSRLVTQRPSQVPGSIMSHRTSGILVSSGGRATSSNVGHVTFGDSSATTGGLMSSRGSIPGRVTFRSPNSSSYLGSTGYVGSSRDHDSFEASKGPGSESSGGLGSSPGPASSPGPASSTGQASSTSKDSQSNY
Protein: Vesicular GABA transporter (A1Z9M6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004439}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004439}.
Interaction partners:
- Molybdenum cofactor synthesis protein cinnamon
- Vesicular acetylcholine transporter
- Glutamate decarboxylase
- Vesicular glutamate transporter, isoform A
- Synaptotagmin 1
- Ras-related protein Rab-3
- DnaJ homolog subfamily C member 5 homolog
- Synaptobrevin
- Heat shock 70 kDa protein cognate 4
- Black, isoform A
Sequence:
MSFIAKLKATPLPPLRNILNVAVQTARQQIPERKDYEQPPGSTAQQHHHSQQAQHKAMEAGMDGGDTTEMSSNPFRNAGSWTNDGEGGGDGDGEYRNEYQSTSFNEYDGRYQQTDGFRQGSIASEGSSFVCEGEGGGGCKIDEFQAAWNVTNAIQGMFIVSLPFAVLHGGYWAIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYVAIAKVCFGPKLGARAVSIAQLIELLMTCILYVVVCGDLLAGTYPQGSFDSRSWMLFVGIFLLPMGFLKSLKMVSTLSFWCTMSHIVINAVILGYCLLQIGDWGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKFNWMLDWSHIAAAVFKAGFGYICFLTFQNDTQQVITNNLHSQGFKGMVNFFLVIKALLSYPLPYYAACELLERNFFRGPPKTKFPTIWNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKIKGHLLDQKEIAKDYLIIGLGVLFGVIGIYDSGNALINAFEIGLPF