wanglab/gogpt-training-data huggingface dataset:
Protein: Calnexin homolog 1 (P29402)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- UDP-glucose:glycoprotein glucosyltransferase
- Heat shock 70 kDa protein BIP3
- Heat shock 70 kDa protein BIP2
- Endoplasmin homolog
- Calreticulin-2
- Calreticulin-1
- Heat shock 70 kDa protein BIP1
- Calnexin homolog 2
- Calreticulin-3
- Probable glucan 1,3-alpha-glucosidase
Sequence:
MRQRQLFSVFLLLLAFVSFQKLCYCDDQTVLYESFDEPFDGRWIVSKNSDYEGVWKHAKSEGHEDYGLLVSEKARKYGIVKELDEPLNLKEGTVVLQYEVRFQEGLECGGAYLKYLRPQEAGWTPQGFDSESPYSIMFGPDKCGGTNKVHFILKHKNPKSGEYVEHHLKFPPSVPYDKLSHVYTAILKPDNEVRILVDGEEKKKANLLSGEDFEPALIPAKTIPDPEDKKPEDWDERAKIPDPNAVKPEDWDEDAPMEIEDEEAEKPEGWLDDEPEEVDDPEATKPEDWDDEEDGMWEAPKIDNPKCEAAPGCGEWKRPMKRNPAYKGKWSSPLIDNPAYKGIWKPRDIPNPDYFELDRPDYEPIAAIGIEIWTMQDGILFDNILIAKDEKVAETYRQTTWKPKFDVEKEKQKAEEEAAGSADGLKSYQKVVFDLLNKVADLSFLSAYKSKITELIEKAEQQPNLTIGVLVAIVVVFFSLFLKLIFGGKKAAAPVEKKKPEVAESSKSGDEAEKKEETAAPRKRQPRRDN
Protein: Leucine-rich repeat (LRR) family protein (Polygalacturonase inhibitor-like protein) (Q9LT39)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Ribonuclease P protein subunit P38-like protein
- Auxin-responsive protein SAUR76
- Phosphatidylinositol 4-phosphate 5-kinase 7
- Pentatricopeptide repeat-containing protein At1g74600
- Peptidyl-prolyl cis-trans isomerase CYP20-3, chloroplastic
Sequence:
MNLNVVVLLLLLLISSATCCPPSDRRALLAFRSALHEPYLGIFNSWTGQDCCHNWYGISCDSLTHRVADINLRGESEDPIFERAHRTGYMTGHISASICELTRLSAITIADWKGISGEIPKCITRLPFLRTLDLIGNQISGGIPYDIGRLNRLAVLNVADNRISGSIPKSLTNLSSLMHLDLRNNLISGVIPSDVGRLKMLSRALLSGNRITGRIPESLTNIYRLADVDLSGNQLYGTIPPSLGRMSVLATLNLDGNKISGEIPQTLMTSSVMNLNLSRNLLQGKIPEGFGPRSYFTVLDLSYNNLKGPIPRSISGASFIGHLDLSHNHLCGRIPVGSPFDHLEAASFMFNDCLCGKPLRACLKN
Protein: Protein STRUBBELIG-RECEPTOR FAMILY 6 (Leucine-rich repeat receptor kinase-like protein SRF6) (Q9C8M9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Heavy metal-associated isoprenylated plant protein 16
Sequence:
MRENWAVVALFTLCIVGFELRFIHGATDASDTSALNTLFSGMHSPAQLTQWTAAAGDPCGQNWRGVTCSGSRVTQIKLSGLELSGTLGGYMLDKLTSLTELDLSSNNLGGDLPYQFPPNLQRLNLANNQFTGAASYSLSQITPLKYLNLGHNQFKGQIAIDFSKLDSLTTLDFSFNSFTNSLPATFSSLTSLKSLYLQNNQFSGTVDVLAGLPLETLNIANNDFTGWIPSSLKGITLIKDGNSFNTGPAPPPPPGTPPIRGSPSRKSGGRESRSSDESTRNGDSKKSGIGAGAIAGIIISLLVVTALLVAFFLFRRKKSKRSSPMDIEKTDNQPFTLASNDFHENNSIQSSSSVETKKLDTSLSINLRPPPIDRNKSFDDEDSTRKPIAVKKSTVVVPSNVRLYSVADLQIATGSFSVDNLLGEGTFGRVYRAEFDDGKVLAVKKIDSSALPHGMTDDFIEMVSKIANLDHPNVTKLVGYCAEHGQHLVVYEFHKNGSLHDFLHLSEEESKALVWNSRVKIALGTARALEYLHEVCSPSIVDKNIKSANILLDSELNPHLSDSGLASFLPTANELLNQTDEGYSAPEVSMSGQYSLKSDIYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHDIDALAKMVDPALKGLYPVKSLSRFADVIALCVQPEPEFRPPMSEVVQALVVLVQRANMSKRTVGVDPSQRAGSADTTSDYM
Protein: Capsid protein (Coat protein) (P69687)
Organism: Tobacco mosaic virus (strain vulgare) (TMV) (Tobacco mosaic virus (strain U1))
Function: Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
Subcellular location: Virion {ECO:0000305}.
Interaction partners:
Sequence:
MSYSITTPSQFVFLSSAWADPIELINLCTNALGNQFQTQQARTVVQRQFSEVWKPSPQVTVRFPDSDFKVYRYNAVLDPLVTALLGAFDTRNRIIEVENQANPTTAETLDATRRVDDATVAIRSAINNLIVELIRGTGSYNRSSFESSSGLVWTSGPAT
Protein: ADAM metallopeptidase with thrombospondin type 1 motif 17 (D3YX90)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MCDGTLLPPLVLSLLLLVWGLDPGTAVGDAAADVEVVLPRRLRPEDVHLQLLPGAAGLRRWRRPRASPGGHRAGQGERALLLHLPAFGRDLYLQLHRDLRFLSPGFEVEEAGVSGRSGHPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLEQEQVFIQPLNSSGGPFIGREHLIRRKWASTPSPATEVEGPRQRCKVVTEKKPRKDHLSRDWRERRNAIRLTNEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHRSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDTPPVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLITDPRSQHALRLPHKLPGMHYSANEQCQILFGTNATFCKNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSLWSAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCQGASVEHAACEKLPCPKGVPSFRDQQCQAHDRLSSKKRGLLTAVVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYEADLCVYGRCQKIGCDGIIGSAAKEDRCGVCSGDGKTCRVVKGDFSHSRGTALKDSSKRSINSDWKIELPGEFQIAGTTVRYVRRGLWEKFSAKGPTTVPLHLMVLLFHDQNYGIHYEYTIPVNQSSENQSEPAKPQDALFLWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVTGQWSPCSATCEKGVQHREVTCVYQLQNGTHVTTRPIYCSEPRPTPVQSCEGQDCLSIWEASEWSECSANCGKGIQKRTVTCTNSQGKCDASTRPKAEEECEDYSGCYEWKTGDWSKCSSTCGKGLQSRVVQCMHKLTGRHGSECPTLSKPAAYRQCHQEVCNEKINVNTITSPRLAALTYKCTRDQWTVYCRVIREKNLCQDMRWYQRCCQTCRDFYADKMRQPPSPPSS
Protein: Rab40 GTPase (Rab40 protein) (Uncharacterized protein LOC495014) (Q5XHF6)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}.
Interaction partners:
- Cullin-5
- Ubiquitin-like domain-containing protein.
Sequence:
MGTQGSPVKSYDYLLKFLLVGDSDVGKGEILESLQDGASESPYSYSNGIDYKTTTILLDGRRVKLELWDTSGQGRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARSYAEKNGMTFFEVSPLCNFNVTESFTELSRIVLMRHGMEKMWRPNKVFSLQDLCCRAIVSCTPVHLIDKLPLPVAIKSHLKSFSMANGMNAVMMHGRSYSVAGSSGGATGSGGGSKGNSLKRSKSIRPPQSPPQNCSRTNCKIS
Protein: Vitellogenin-2 (Vitellogenin II) (Yolk protein 2) (P02844)
Organism: Drosophila melanogaster (Fruit fly)
Function: Vitellogenin is the major yolk protein of eggs where it is used as a food source during embryogenesis.
Subcellular location: Secreted.
Interaction partners:
- Vitellogenin-1
- Vitellogenin-3
- Vitelline membrane protein Vm26Aa
- Vitelline membrane protein Vm34Ca
Sequence:
MNPLRTLCVMACLLAVAMGNPQSGNRSGRRSNSLDNVEQPSNWVNPREVEELPNLKEVTLKKLQEMSLEEGATLLDKLYHLSQFNHVFKPDYTPEPSQIRGYIVGERGQKIEFNLNTLVEKVKRQQKFGDDEVTIFIQGLPETNTQVQKATRKLVQAYQQRYNLQPYETTDYSNEEQSQRSSSEEQQTQRRKQNGEQDDTKTGDLIVIQLGNAIEDFEQYATLNIERLGEIIGNRLVELTNTVNVPQEIIHLIGSGPAAHVAGVAGRQFTRQTGHKLRRITALDPTKIYGKPEERLTGLARGDADFVDAIHTSAYGMGTSQRLANVDFFPNGPSTGVPGADNVVEATMRATRYFAESVRPGNERNFPSVAASSYQEYKQNKGYGKRGYMGIATDFDLQGDYILQVNSKSPFGRSTPAQKQTGYHQVHQPWRQSSSNQGSRRQ
Protein: Phenylalanine ammonia-lyase (PAL) (EC 4.3.1.24) (P35511)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Uncharacterized protein
- trans-cinnamate 4-monooxygenase
- RING-type domain-containing protein
- histidinol-phosphate transaminase
- Tyrosine decarboxylase
- Tyrosine decarboxylase
- Tryptophan decarboxylase
- Tryptophan decarboxylase
- Aminotransferase class I/classII large domain-containing protein
- Aminotransferase class I/classII large domain-containing protein
Sequence:
MDLCKKSINDPLNWEMAADSLRGSHLDEVKKMVDEFRKPIVKLGGETLSVAQVASIANVDDKSNGVKVELSESARAGVKASSDWVMDSMSKGTDSYGVTAGFGATSHRRTKNGGALQKELIRFLNAGVFGNGIESFHTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKLINSNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGPNGEKLNAEEAFCVAGISGGFFELQPKEGLALVNGTAVGSAMASIVLFESNIFAVMSEVLSAIFTEVMNGKPEFTDYLTHKLKHHPGQIEAAAIMEHILDGSSYVKVAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLALASIGKLMFAQFSELVNDYYNNGLPSNLTAGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISARKTAKAVDILKIMSSTYLVALCQAIDLRHLEENLKSVVKNTVSQVAKRTLTMGANGELHPARFSEKELLRVVDREYLFAYADDPCSSNYPLMQKLRQVLVDQAMKNGESEKNVNSSIFQKIGAFEDELIAVLPKEVESVRAVFESGNPLIRNRITECRSYPLYRLVREELGTELLTGEKVRSPGEEIDKVFTAICNGQIIDPLLECLKSWNGAPLPIC
Protein: Leucine-rich repeat protein kinase (Leucine-rich repeat receptor-like protein kinase) (Serine/threonine-specific receptor protein kinase-like protein) (Q9M0D8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Putative RING zinc finger protein
- Protein-protein interaction regulator family protein
Sequence:
MRANLVFGIFCALVTTILVHGQDQSGYISIDCGIPPYDTPEDTMTNINYVSDEAFITTGVNFKVSEEYGYPKNPVLLSTLAEVRAFPQGNRNCYTLKLSQGKDHLYLIRASFMYGNYDGKKALPEFDLYVNVNFWSTVKFKNASDQVTKEILSFAESDTIYVCLVNKGKGTPFISGLELRPVNSSIYGTEFGRNVSLVLYRRWDIGYLNGTGRYQDDRFDRIWSPYSSNISWNSIITSGYIDVFQNGYCPPDEVIKTAAAPENVDDPLELFWTSDDPNVRFYAYLYFAELETLEKNETRKIKILWNGSPVSETSFEPSSKYSTTFSNPRAFTGKDHWISIQKTVDSTLPPILNAIEIFTAQSLDEFSTTIEDIHAIESIKATYKVNKVWSGDPCSPRLFPWEGVGCSDNNNNHQIKSLNLSSSGLLGPIVLAFRNLSLLESLDLSNNDLQQNVPEFLADLKHLKVLNLKGNNFTGFIPKSLMKKLKAGLLTLSADEQNLCNSCQEKKKKKSMVVPIAVAASVIVLVVVLVIIWIILRQRKKGAYSGPLLPSGKRRFTYNEVSSITNNFNKVIGKGGFGIVYLGSLEDGTKIAVKMINDSSLAKPKGTSSSSLSRASNQFQVEAELLLTVHHRNLASFVGYCDDDRSMALIYEYMANGNLQAYLSSENAEDLSWEKRLHIAIDSAQGLEYLHDGCRPAIVHRDVKTANILINDNLEAKIADFGLSKVFPEDDLSHVVTTVMGTPGYVDPEYYRTFVLNEKSDVYSFGVVLLELITGQRAIIKTEEGDNISVIHYVWPFFEARELDGVVDPLLRGDFSQDSAWKFVDVAMSCVRDKGSNRPTMNQIVAELKQCLAAELDREPQSQ
Protein: Protein NAP1 (ARP2/3 regulatory protein subunit NAPP) (NAP of plants) (Nck-associated protein 1) (AtNAP1) (AtNAP125) (Protein GNARLED) (p125Nap1) (Q5S2C4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Interaction partners:
- Protein PIR
- Protein ABIL1
- Protein BRICK 1
- Actin-related protein 2
- Actin-related protein 2/3 complex subunit 2A
- Dirigent protein 18
- Dirigent protein 16
- Actin-related protein 2/3 complex subunit 3
- AT3G19900 protein
- BTB/POZ domain-containing protein At3g19850
Sequence:
MANSRQYYPSQDESMSPTSVRSREWEGPSRWTEYLGPEMAASVSSTRSSKQIDGHVGGSTKALNIQWVVQMIEVADGLMAKMYRLNQILEYPDPVGHVFSEAFWKAGVFPNHPRICTLLSKKFPEHFSKLQLERIDKFSLDSLHDGAELHLQSLEPWIQLLLDLMAFREQALRLILDLSSTVITLLPHQNSLILHAFMDLFCAFVRVNLFAEKIPRKMLLQVYNLLHALSRNDRDCDFYHRLVQFIDSYDPPLKGLQEDLNFVSPRIGEVLEAVGPSIFLSADTRKLRNEGFLSPYHPRFPDILTNSAHPMRAQDLANVTSYREWVLLGYLVCPDELLRVTSIDIALVVLKENLVVTLFRDEVSLYQMVCEKEFGIGISFASADSINLTMQYILLHEDYQLYVLPRVLESKKMAKSGRTKQKEADLEYSVAKQVEKMISEVHEQALQLCDTIHRERRILLKQEIGRMVLFFTDQPSLLAPNIQMVFSALALAQSEVLWYFQHAGIASSRSKAARVIPVDIDPNDPTIGFLLDGMDRLCCLVRKYISAARGYALSYLSSSAGRIRYLMGTPGIVALDLDPTLKGLFQRIVQHLESIPKAQGENVSAITCDLSDFRKDWLSILMIVTSSRSSINIRHLEKATVSTGKEGLLSEGNAAYNWSRCVDELESQLSKHGSLKKLYFYHQHLTTVFRNTMFGPEGRPQHCCAWLSVASSFPECASLIIPEEVTKFGRDAVLYVESLIESIMGGLEGLINILDSEGGFGALESQLLPEQAAAYLNNASRISAPSVKSPRVVGGFTLPGHESYPENNKSIKMLEAAIQRLTNLCSILNDMEPICVINHVFVLREYMRECILGNFKRRFLTALQTDNDLQRPSVLESLIRRHMGIVHLAEQHVSMDLTQGIREILLTEAFSGPVSSLHTFEKPAEQQQTTGSAVEVVCNWYMDNIIKDVSGAGILFAPRHKYFKSTRPVGGYFAESVTDLKELQAFVRIFGGYGVDRLDRMMKVHTAALVNCIETSLRSNRELIEAAAASMHSGDRVERDASVRQIVDLDTVIGFCIEAGQALAFDDLLAEASGAVLEDNASLIHSMISGIVEHIPEEIPEKKEIRRIKGVANGVGVAGDHDSEWVRLILEEVGGANDNSWSLLPYFFASFMTSNAWNTTGFNIETGGFSNNIHCLARCISAVIAGSEYVRLQREYQQQHQSLSNGHHSSENLDSEFPPRVTAEASIKSSMLLFVKFAASIVLDSWSEANRSHLVAKLIFLDQLCEISPYLPRSSLESHVPYTILRSIYTQYYSNTPSTPLSTASPYHSPSVSLIHASPSMKNSTTPQRGSGSGSSSTAAPDSGYFKGSSSSLYGQEHYTESETGNSRNNENNNNNKQRGSSRRSGPLDYSSSHKGGSGSNSTGPSPLPRFAVSRSGPISYKQHN
Protein: Brahma-associated protein of 60 kDa (BRM-associated protein 60) (Q9VYG2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the recruitment and site-specific anchoring of the Brahma complex at specific promoter sites. The Brahma complex is a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Participates in X-chromosomal dosage compensation. Participates in neurogenesis.
Interaction partners:
- Brahma associated protein 111kD
- Brahma associated protein 55kD
- ATP-dependent helicase brm
- GH08712p
- Brahma associated protein 155 kDa
- Polybromo
- Brahma associated protein 170kD
- Supporter of activation of yellow protein
- Bromodomain containing 7/9
- Trithorax group protein osa
Sequence:
MSQRFAPGQAPVQSRYQPPPPAPGMRPYPPPGASFPPRGFPLHPNTTQPVPGTANVAGVPGVPGVPGVPGPSLLQRAAQQPGFQSSLRGTGAGGGGVGSGGGSKRSNESRSLGGGGSKSDFATAKKKKKLAEKILPQKVRDLVPESQAYMDLLTFERKLDATIMRKRLDIQEALKRPMKQKRKLRIFISNTFYPSKEPTNDGEEGAVASWELRVEGRLLEDGKGDPNTKIKRKFSSFFKSLVIELDKELYGPDNHLVEWHRTHTTQETDGFQVKRPGDRNVRCTILLLLDYQPLQFKLDPRLARLLGVHTQTRPVIISALWQYIKTHKLQDAHEREYINCDKYLEQIFSCQRMKFAEIPQRLNPLLHPPDPIVINHFIESGAENKQTACYDIDVEVDDTLKNQMNSFLMSTASQQEIQGLDTKIHETVDTINQMKTNREFFLSFAKDPQMFIHRWIISETRDLKLMTDVAGNPEEERRAEFYYQPWTHEAVSRYFFTKVNQKRAELEQALGIRNG
Protein: 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase (EC 3.7.1.14) (2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase) (P77044)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. MhpC shows some selectivity for the carboxylate of the side chain.
Interaction partners:
- 2-keto-4-pentenoate hydratase
- 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase
- 4-hydroxy-2-oxovalerate aldolase
- 3-
- Acetaldehyde dehydrogenase
- 3-phenylpropionate/cinnamic acid dioxygenase subunit beta
- 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenasepropanoate dehydrogenase)
- DNA-binding transcriptional activator MhpR
- 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha
Sequence:
MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSVVNSGSRSDLNARILKSVVDQLDIAKIHLLGNSMGGHSSVAFTLKWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFLARP
Protein: Gamma-crystallin F (Gamma-F-crystallin) (Gamma-crystallin 4-1) (P10068)
Organism: Rattus norvegicus (Rat)
Function: Crystallins are the dominant structural components of the vertebrate eye lens.
Interaction partners:
- Gamma-crystallin B
- Gamma-crystallin A.
Sequence:
MGKITFYEDRGFQGRHYECSTDHSNLQPYFSRCNSVRVDSGCWMLYEQPNFTGCQYFLRRGDYPDYQQWMGFSDSVRSCHLIPHSSSHRIRIYEREDYRGQMVEITDDCPHLQDRFHFSDFHSFHVIEGYWVLYEMPNYRGRQYLLRPREYRRYHDWGAMNARVGSLRRIMDYY
Protein: GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] (Q9JHZ4)
Organism: Rattus norvegicus (Rat)
Function: Regulates the endosomal recycling back to the neuronal plasma membrane, possibly by connecting early and late recycling endosomal domains and promoting segregation of recycling endosomes from early endosomal membranes. Involved in the localization of recycling endosomes to dendritic spines, thereby playing a role in the maintenance of dendritic spine morphology. Required for the activity-induced AMPA receptor recycling to dendrite membranes and for long-term potentiation and synaptic plasticity.
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:20098723}; Peripheral membrane protein {ECO:0000305}. Recycling endosome membrane {ECO:0000269|PubMed:20098723}; Peripheral membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000269|PubMed:20098723}. Cell projection, dendrite {ECO:0000269|PubMed:20098723}. Synapse {ECO:0000269|PubMed:20098723}. Note=Localizes to recycling endosomal tubules that are emanating from early endosomes. {ECO:0000269|PubMed:20098723}.
Interaction partners:
- Glutamate receptor-interacting protein 1
- Ras-related protein Rab-4A
- Vacuolar protein sorting-associated protein 41 homolog
- CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
- Syntaxin-12
- Glutamate receptor-interacting protein 2
Sequence:
MAQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSEKEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEGVPGAAGPHVDGELLRLQAENTALQKNMAALQERYGKEAVRPSAVSEGQGDPPGDVLPISLSPMPLAEVELKWEMEREEKKLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSSQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQNTELAAELKHRQADYEELMGQKDDLNSQLQESLRANSRLLEQLQEMGQEKEQLIQDLQEARKSAEKRKVMLDELAMETLQEKSQHKEELGAVRLRHEKEMLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQAQVHSMDGAKGWFERRLKEAEESLLQQEQEQEETLKQCREQHAAELKGKEEELQNVRDQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRADKLQERLQEILTNSKSRTGLEELVLSEMNSPSRTQTGDSSSVSSFSYREILKEKESSAIPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSPDPDLEPGEAN
Protein: Transcription factor ROB1 (Regulator of biofilm 1) (A0A1D8PFP2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
Interaction partners:
- Biofilm regulator 1
- Biofilm and cell wall regulator 1
- Transcription activator TEC1
- Transcription factor NDT80
- Enhanced filamentous growth protein 1
- RFX-like DNA-binding protein RFX2
- Transcriptional regulator of filamentous growth FLO8
- Hyphal wall protein 1
Sequence:
MTPSSTKKIKQRRSTSCTVCRTIKRKCDGNTPCSNCLKRNQECIYPDVDKRKKRYSIEYITNLENTNQQLHDQLQSLIDLKDNPYQLHLKITEILESSSSFLDNSETKSDSSLGSPELSKSEASLANSFTLGGELVVSSREQGANFHVHLNQQQQQQQPSPQSLSQSSASEVSTRSSPASPNSTISLAPQILRIPSRPFQQQTRQNLLRQSDLPLHYPISGKTSGPNASNITGSIASTISGSRKSSISVDISPPPSLPVFPTSGPTLPTLLPEPLPRNDFDFAPKFFPAPGGKSNMAFGATTVYDADESMVMNVNQIEERWGTGIKLAKLRNVPNIQNRSSSSSSTLIKVNKRTIEEVIKMITNSKAKKYFALAFKYFDRPILCYLIPRGKVIKLYEEICAHKNDLATVEDILGLYPTNQFISIELIAALIASGALYDDNIDCVREYLTLSKTEMFINNSGCLVFNESSYPKLQAMLVCALLELGLGELTTAWELSGIALRMGIDLGFDSFIYDDSDKEIDNLRNLVFWGSYIIDKYAGLIFGRITMLYVDNSVPLIFLPNRQGKLPCLAQLIIDTQPMISSIYETIPETKNDPEMSKKIFLERYNLLQGYNKSLGAWKRGLSREYFWNKSILINTITDESVDHSLKIAYYLIFLIMNKPFLKLPIGSDIDTFIEIVDEMEIIMRYIPDDKHLLNLVVYYALVLMIQSLVAQVSYTNANNYTQNSKFMNQLLFFIDRMGEVLRVDIWLICKKVHSNFQQKVEYLEKLMLDLTEKMEQRRRDEENLMMQQEEFYAQQQQQQQQQQQQPKHEYHDHQQEQEQQEQLQEEHSEKDIKIEIKDEPQPQEEHIHQDYPMKEEEENLNQLSEPQTNEEDNPAEDMLQNEQFMRMVDILFIRGIENDQEEGEEQQQQQQQQEQVQQEQVQQEQVQQDQMELEEDELPQQMPTSPEQPDEPEIPQLPEILDPTFFNSIVDNNGSTFNNIFSFDTEGFRL
Protein: Myelin-oligodendrocyte glycoprotein (Q63345)
Organism: Rattus norvegicus (Rat)
Function: Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Myelin basic protein
- Myelin-associated glycoprotein
- Myelin-associated oligodendrocyte basic protein
- T-cell surface glycoprotein CD4
- Myelin proteolipid protein
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase
- Rano class II histocompatibility antigen, B-1 beta chain
- Aquaporin-4
- Interferon gamma
- Interleukin-17A
Sequence:
MAGVWSLSLPSCLLSLLLLLQLSRSYAGQFRVIGPGHPIRALVGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKESIGEGKVALRIQNVRFSDEGGYTCFFRDHSYQEEAAVELKVEDPFYWINPGVLALIALVPMLLLQVSVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGQFLEELRNPF
Protein: HtrA serine peptidase 2 (A0A8I6AYW8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAALKAGRGANWSLRAWRALGGIFWRKGPLLAPDLRALLTSGTPDPQARMTYGTPSLPARVPLGVLASRANLTSGTPDLWVRLTVGTPGSSDQEDCGSPGSRRREWLAVALGAGGAVLLLLWGWGRGPSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPISNGSGFIVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRRYIGVMMLTLTPRAGLRPADVILAIGEKMIQNAEDVYEAVRTQSQLAVRIRRGPETLTLYVTPEVT
Protein: Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R) (P78417)
Organism: Homo sapiens (Human)
Function: Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:11511179}.
Interaction partners:
- Glutathione reductase, mitochondrial
- Peroxiredoxin-6
- Hematopoietic prostaglandin D synthase
- Glutathione synthetase
- Phospholipid hydroperoxide glutathione peroxidase GPX4
- Epoxide hydrolase 1
- Cytochrome P450 1B1
- Cytochrome P450 2E1
- Cytochrome P450 1A1
- Cytochrome P450 1A2
Sequence:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
Protein: Succinate--CoA ligase [ADP-forming] subunit alpha (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) (P9WGC7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
Interaction partners:
- Succinate--CoA ligase subunit beta
- Multifunctional 2-oxoglutarate metabolism enzyme
- succinate dehydrogenase
- Succinate dehydrogenase flavoprotein subunit
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
- Succinate dehydrogenase 2 membrane subunit SdhC
- Probable succinate dehydrogenase [iron-sulfur subunit]
- 2-oxoglutarate oxidoreductase subunit KorA
- Probable succinate dehydrogenase [iron-sulfur subunit]
- Fumarate reductase iron-sulfur subunit
Sequence:
MTHMSIFLSRDNKVIVQGITGSEATVHTARMLRAGTQIVGGVNARKAGTTVTHEDKGGRLIKLPVFGSVAEAMEKTGADVSIIFVPPTFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYAWAYNLEAGHKTRIIGPNCPGIISPGQSLAGITPANITGPGPIGLVSKSGTLTYQMMFELRDLGFSTAIGIGGDPVIGTTHIDAIEAFERDPDTKLIVMIGEIGGDAEERAADFIKTNVSKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAAAKQEALEAAGVKVGKTPSATAALAREILLSL
Protein: AAA+ ATPase domain-containing protein (Q383E3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQSTSAGSDFALGTSVPPFLELLPLLVILLIFAFGIQAVVLLSKSRWEDQQGNGEGEVVRTITGTFYRSSFYHRFYENSKCEHTGILLSSTLLNIARHVQNGSKQLVCTTVYPRDARHGPDKQSVLFLFDPLKSDSELVLGPSSFESTGFFYAGVALRGFNLRDQLPRYAVASLPTCGMWITVDDGIEVTYQRCRKDEDFAQRVDHVLYLKARGPGAAQKLERFVDQSLKEYISNLPRTAGGQQYHFQLTGGEKTLQFTKQLLSTSKTFDTLFFSQKDELLSRLEQFVEKKGRFAIEGFPYKLGFLVYGESGVGKTALVSAIAAYTGRHVISLHLPIISTDQQLSDIFLTRTLRCTKDFQPFVYELDDVIFLFEDVDASDDLVRCRQASTGQGPEGGNQCGYGLGGVASQQARCDGRYKVPGLSGFLNVLDGVVDMHSLIVVMTTRDPNDIDSALLRPGRFGYKIHMENMRTDELVGLVGLHFGTEQRHTAEVEGKTEGERSVNAGRNLYRLSRADEKTVREYIVSRCGEEFSINGRVAEAMCMGSDTLDEFLARLAKWYGEK