wanglab/gogpt-training-data huggingface dataset:
Protein: Trafficking protein particle complex subunit 9 (A0A8I6AL85)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
Sequence:
MSVPDYMQCAEDHQTLLVVVQAVGIVSEENFFRIYKRICSVSQLSVRDSQRALFIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSPKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGDVAEQPRPDVAFYPNYDDCDSVEKRIEDFIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDALVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKTGARRLPGNSLPSEAANRHRPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACVKAVRVLAIQKRGMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFNKGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVTQSLENYTAKCPGTMEPITLPDGLTLPPVPFTKLPIVRCVKLLSLPTSLRPQKVKSLLGQSMSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGMITVNGYHTTVFGVFSDCLLDNLPGLKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSAGDEIATNVSVQLFNGETQQLAITLENIGLEPLEQLEVTSKLLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKAKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVESRPTNPSEGSKTGDLGHVKVSPSVEVQAARVGSPGFCWSTFQLAFGVPF
Protein: Myocyte enhancer factor 2A isoform 5 (A0A0S2Z4C8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRKKIQITRIMDERNRQTLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT
Protein: Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog) (Q14CW9)
Organism: Homo sapiens (Human)
Function: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03047, ECO:0000269|PubMed:27601583}.
Interaction partners:
- Transcription and mRNA export factor ENY2
- Ubiquitin carboxyl-terminal hydrolase 22
- Ataxin-7
- Transformation/transcription domain-associated protein
- Transcriptional adapter 3
- TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
- Transcription factor SPT20 homolog
- Transcription initiation factor TFIID subunit 12
- Histone acetyltransferase KAT2A
- Transcriptional adapter 1
Sequence:
MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKDFEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN
Protein: Eukaryotic translation initiation factor 4 gamma 2 (Q0E996)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MYAQLCKRLSEEAPSFDKEPSNSSTFLRLLIAVCRDKFNNRLKRDENDNRPPPENEADEEERRHLAKQRMLGNVKFIGELNKLDMLSKNVLHQCIMELFDKKKKRTAGTQEMCEDMECLAQLLKTCGKNLDSEQGKELMNQYFEKLERRSKSSEYPPRIRFMLKDVIELRQNNWVPRKLGTTEGPVPIKQIRSDDDSIIRTPFPNRNRDMRNNDRDSDSWMNRFHLNIQPGGYNDMFSGLSVTGASPIVSPFATSNRDRDRDNRQYNNRGDRNRDRDQGGSGGANYGNRYNKHNQNGGGSGGGSSNNRDRDDSRRNNDRDRDRNDGQYGGNQLLGSKELAPRFKRNLITTNQDAVENLQMRPAANSLLFRAASQNQKFPATLPMSTPPNSSGSNNQGSSQGQLSNSHYPMLGTPTSHLINPTRPSSTPSAEYADNRTLLGVQQERGLKATSSSPNFSSGAEKLDLDGQAGRKGSHDGKDQGKNGSVERPSTPAGGIGSAKQQKKDKGPNKEELSKKASQYFKDRFYYDEEEDAEVTEIEIKDIDETKTEEADAAPVEVSEVKEDAAIPVTTPDRFTKLVDGFLELKLPEKALKDVCINLLMEVLDRVNDVFLERAVRLLQTLRKQSNIKPNIVVEIFKQVVNKMNEREALNPRIVSLVASLLAKTICEPALLKLSDIANFTDNGQHYPLFLLVLQQLVKVIGKDALEEKFRASKVDLMNSLPEADRNKERLAGILEDRKLSFLYPLLKVQAEMLKQLQSDPNPNNFYKWIKANVDNKYYKDPGFIQALMTVVVKYVTKETTLADNLDPKEHPEKSVTQKEQQLLENYSQMLQTFLGQNELQLMALYALQTFCYNENFPKGMLCRWFKYLYESEIIEEEAFVLWKEEISDKYPGKGSALFQVNAWLTWLQEAESEDDED
Protein: DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (E5KPN1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLRQSRHAQEPPAKRRKGSKGPEG
Protein: E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13) (O60858)
Organism: Homo sapiens (Human)
Function: Endoplasmic reticulum (ER) membrane anchored E3 ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor. Also plays a role in innate immune response by stimulating NF-kappa-B activity in the TLR2 signaling pathway. Ubiquitinates TRAF6 via the 'Lys-29'-linked polyubiquitination chain resulting in NF-kappa-B activation. Participates as well in T-cell receptor-mediated NF-kappa-B activation. In the presence of TNF, modulates the IKK complex by regulating IKBKG/NEMO ubiquitination leading to the repression of NF-kappa-B.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:17314412, ECO:0000269|PubMed:21333377, ECO:0000269|PubMed:22178386, ECO:0000269|PubMed:25152375}; Single-pass membrane protein {ECO:0000269|PubMed:17314412, ECO:0000269|PubMed:21333377, ECO:0000269|PubMed:22178386}. Note=Concentrates and colocalizes with p62/SQSTM1 and ZFYVE1 at the perinuclear endoplasmic reticulum.
Interaction partners:
- Potassium channel regulatory protein
- Proenkephalin-B
- Solute carrier family 25 member 16
- Gamma-secretase subunit PEN-2
- Protein jagged-2
- T-cell receptor-associated transmembrane adapter 1
- Transitional endoplasmic reticulum ATPase
- T-cell surface glycoprotein CD5
Sequence:
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Protein: WRKY transcription factor 1 (Transcription factor ZAP1) (WRKY DNA-binding protein 1) (Zinc-dependent activator protein 1) (Q9SI37)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Binds to a 5'-CGTTGACCGAG-3' consensus core sequence which contains a W box, a frequently occurring elicitor-responsive cis-acting element.
Subcellular location: Nucleus {ECO:0000269|PubMed:17264121}.
Interaction partners:
- Probable WRKY transcription factor 2
- Transcription repressor MYB6
Sequence:
MAEVGKVLASDMELDHSNETKAVDDVVATTDKAEVIPVAVTRTETVVESLESTDCKELEKLVPHTVASQSEVDVASPVSEKAPKVSESSGALSLQSGSEGNSPFIREKVMEDGYNWRKYGQKLVKGNEFVRSYYRCTHPNCKAKKQLERSAGGQVVDTVYFGEHDHPKPLAGAVPINQDKRSDVFTAVSKGEQRIDIVSLIYKLCIVSYDIMFVEKTSGSSVQTLRQTEPPKIHGGLHVSVIPPADDVKTDISQSSRITGDNTHKDYNSPTAKRRKKGGNIELSPVERSTNDSRIVVHTQTLFDIVNDGYRWRKYGQKSVKGSPYPRSYYRCSSPGCPVKKHVERSSHDTKLLITTYEGKHDHDMPPGRVVTHNNMLDSEVDDKEGDANKTPQSSTLQSITKDQHVEDHLRKKTKTNGFEKSLDQGPVLDEKLKEEIKERSDANKDHAANHAKPEAKSDDKTTVCQEKAVGTLESEEQKPKTEPAQS
Protein: phosphoglycerate dehydrogenase (EC 1.1.1.95) (Q6FIP3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Phosphoserine aminotransferase
- Candida glabrata strain CBS138 chromosome K complete sequence
- Phosphoglycerate mutase
- Phosphoglycerate mutase
- alanine--glyoxylate transaminase
- Histidine biosynthesis trifunctional protein
- Serine hydroxymethyltransferase, cytosolic
- phosphoserine phosphatase
- Aminomethyltransferase
- Serine hydroxymethyltransferase, mitochondrial
Sequence:
MDINPLQDSFQRAMNLSRSPGAVSTSPTQSFMNTLPRRLSVSKQQKALKPFSTGDMRILLLENVNQTAVDIFKDQGYQVEFYKSSLPEEELIEKIKDVHAIGIRSKTKLTANILKHAKNLVVIGCFCIGTNQVDLDYAASIGVAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVSQKCWEVRGKTLGVVGYGHIGSQLSVLAESMGMHVLYYDIVTIMALGTAKQVSTLDELLNKSDFVTLHVPETPETKNLLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAMKAGKIAGAALDVYPNEPAKNGADAFSDKLNNWTSELVSLPNVILTPHIGGSTEEAQSAIGIEVAHALSKYINEGISVGSVNFPEVSLRSLDLDQENTVRVLYIHKNVPGVLKTVNNILSNHNIEKQFSDSCGEIAYLMADISDVNQSDIKQIYDELDKTSSKISIRLLY
Protein: IP09930p (Q1RKU6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDALIPLLTDPKQRDFPMWLPVPPTYCAYNQDINLEANHSASDRPTSHIITTTHSESYYRNTKMENSSSYTHKKFAVSKRKREVDHDKENQTQQSEQPIFKRRQTQGFFRPWLDNEQNQQAEKETSTAAKPSGPGSSVSQYRANMVRRSNTNRQRSPKEQMRRDRNTLACLLSRRAKQAQEEQVGQQYEQYRSHHAAMLEQQVRLSLYYRHILQQAVFQRAINPAPGHILPQQQQQFLQQMALSQQMLIFGGQHC
Protein: Short-chain dehydrogenase reductase ATA1 (EC 1.1.1.-) (Protein TAPETUM 1) (ATA1) (Tasselseed-2 homolog ATA1) (Q9M1K9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in tapetum development.
Interaction partners:
- Transcription factor DYT1
- Transcription factor bHLH91
- Transcription factor MYB35
- Transcription factor MYB80
- Transcription factor bHLH89
- Leucine-rich repeat receptor protein kinase EMS1
- Cytochrome P450 703A2
- Type III polyketide synthase B
- ABC transporter G family member 26
- Transcription factor bHLH10
Sequence:
MANSDKRLFEKVAIITGGARGIGAATARLFTENGAYVIVADILENEGILVAESIGGCYVHCDVSKEADVEAAVELAMRRKGRLDVMFNNAGMSLNEGSIMGMDVDMVNKLVSVNVNGVLHGIKHAAKAMIKGGRGGSIICTSSSSGLMGGLGGHAYTLSKGAINGVVRTTACELGSHGIRVNSISPHGVPTDILVNAYRKFLNHDKLNVAEVTDIIAEKGSLLTGRAGTVEDVAQAALFLASQESSGFITGHNLVVDGGYTSATSTMRFIYN
Protein: Exopolyphosphatase (ExopolyPase) (EC 3.6.1.11) (Polyphosphate:ADP phosphotransferase) (PolyP:ADP phosphotransferase) (EC 2.7.4.1) (Q9ZN70)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. Has also polyphosphate:ADP phosphotransferase activity, catalyzing the production of ATP from ADP and polyP.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P0AFL6}; Peripheral membrane protein {ECO:0000250|UniProtKB:P0AFL6}.
Interaction partners:
- Polyphosphate kinase
- GTP pyrophosphokinase
- GDP-polyphosphate phosphotransferase
- guanosine-3',5'-bis
- Polyphosphate:AMP phosphotransferase
- Inorganic pyrophosphatase
- Phosphate-specific transport system accessory protein PhoU homolog
- Alkaline phosphatase L
Sequence:
MDLQSMPQKPAEAFPLIAALDLGSNSFHLCLAKANIHGEVRILERLGEKVQLAAGLDEERNLSEEATQRGLDCLRRFAQFISGMPQGSVRVVATNALREARNRSDFIRRAEEVLGHPVEVISGREEARLIYLGVANSMPDSGGRRLVSDIGGGSTEFIIGQGFESELRESLQMGCVSYTQRYFRDGKITPARYAQAYTAARLELMGIENSLRRLGWQQAVGASGTIRAVALAIKAGGHGNGEISPDGLAWLKRKVLKLGDVEKLDLEGIKPDRRTIFPAGLAILEAIFDALELEQMVHSEGALREGVLYDLVGRHQHEDVRERTISSLMQRYHVDPEQASRVEAKALKVLAEVGDAWELNGELHRDLLSWGARVHEIGLDIAHYHYHKHGAYLIEHSDLAGFSRQDQQMLSLLVRGHRRNIPADKLAEFAEEGDKLVRLCIVLRFAILFHHIRGTQEMPSVRLKAEPKSLSVTFPEGWLEANPLTQADFAQEAEWLKRVGYSLNVR
Protein: Poly(rC) binding protein 2 (A0A8I6AGT9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS
Protein: Uncharacterized hydrolase YNR064C (EC 3.1.-.-) (P53750)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
Sequence:
MSNIIARFHKIQVQDGVKVWYREAGAAGNPTILLLHGFPTSSNMFRNLIPLLAGQFHIIAPDLPGFGFTETPENYKFSFDSLCESIGYLLDTLSIEKFAMYIFDYGSPVGFRLALKFPSRITGIVTQNGNAYEEGLDDRFWGPLKEYWKSYQSDPVFVKSLIPYLEDPANVICQYHDGVPAIESVDPAAYTLDIALIQRTGQTDIQLRLFFDYQNNIKLYPAFQKFLRDSKIPVLVAWGANDTIFSVAGAEAYRKDVDNLKVVYYDTGHFALETHVVAIAEEIISMFAEN
Protein: Zinc finger protein 829 (Q3KNS6)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger protein 570
Sequence:
MPHSPLISIPHVWCHPEEEERMHDELLQAVSKGPVMFRDVSIDFSQEEWECLDADQMNLYKEVMLENFSNLVSVGLSNSKPAVISLLEQGKEPWMVDRELTRGLCSDLESMCETKILSLKKRHFSQVIITREDMSTFIQPTFLIPPQKTMSEEKPWECKICGKTFNQNSQFIQHQRIHFGEKHYESKEYGKSFSRGSLVTRHQRIHTGKKPYECKECGKAFSCSSYFSQHQRIHTGEKPYECKECGKAFKYCSNLNDHQRIHTGEKPYECKVCGKAFTKSSQLFLHLRIHTGEKPYECKECGKAFTQHSRLIQHQRMHTGEKPYECKQCGKAFNSASTLTNHHRIHAGEKLYECEECRKAFIQSSELIQHQRIHTDEKPYECNECGKAFNKGSNLTRHQRIHTGEKPYDCKECGKAFGSRSDLIRHEGIHTG
Protein: Proteasomal ubiquitin receptor ADRM1 homolog rpn1301 (Regulatory particle non-ATPase 13a protein) (Q9Y7Y6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Ccomponent of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor (Probable).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- 26S proteasome regulatory subunit rpn12
- 26S proteasome regulatory subunit 4 homolog
- 26S proteasome regulatory subunit rpn2
- 26S proteasome regulatory subunit rpn11
- 26S proteasome regulatory subunit rpn10
- 26S proteasome regulatory subunit 6B homolog
- 26S proteasome regulatory subunit rpn1
- Probable 26S proteasome regulatory subunit rpn3
- 26S proteasome regulatory subunit 7 homolog
- 26S proteasome regulatory subunit 6A
Sequence:
MSLITFKAGKLRRVPGTKLLRADPEKGYIVMNRDAYGLIHFQWAKRNDLENPEDDIIVFSSECTFEKVTECTTGRAYMLKYPSSAHSLFYWMQEASDDNDTSYAERINSYIKDQDLLDPARSDVATVSDMMEVDTVEQSEPIAQPTESSKESSEIGAPNSDEINSSEAVRNLLATISAQAGFGGSTVDLCEILKPSNLTDLLCQEGVIDRLMPYMPPDTPNNLEGVLAIVSSPQYAQALRSFSQALNSPGGVNIISALGLSLDESANPNEGGALQFLKAIARFVSRNNGSE
Protein: Glycosyltransferase 1 domain containing 1 (F5H088)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLTARCLSDDTLAHLEAAGHVCVLKDAFDFESRSEIANLILAENCEAALALHLYRGGRLLQGHRIPFGVIFGGTDVNEDANQAEKNTVMGRVLEEARFAVAFTESMKEMAQAQWKARQISLAVTSAVPVQPHAKGKVYVQSQGIATTPNAAFNWNTFLQRSEINQSADNLHIFLLICGLRQVKDPLYLVDAFSAWHQEEPNVHLVIVGPEVDPVFTREVKAKVKRAAGVRLIGEMPQEDLHAVVKNCFAVVNSSVSEGMSAAILEAMDLEVPVLARNIPGNAAVVKHEVTGLLFSNPQEFVHLAKRLVSDPALEKEIVVNGREYVRMYHSWQVERDTYQQLIRKLEGSTED
Protein: Elongation factor Tu (Q9FUZ6)
Organism: Zea mays (Maize)
Interaction partners:
Sequence:
MASAAVLRNAGSRRLFSYPTLRAAAIYVPSALPDAPAAAAAPAQPPPTAGTLWARSMATFTRTKPHVTVGTIGHVDHGKTTLTAAITKVLAEAGKAKAVAFDEIDKAPEEKARGITIATAHVEYETAKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAPDGPMPQTKEHILLARQVGVPSLVCFLNKVDAVDDPELLELVEMELRELLSFYKFPGDEIPIIRGSALSALQGNNDEIGKNAILKLMDAVDEYIPDPVRQLDKPFLMPIEDVFSIQGRGTVVTGRVEQGTIKTGEDVEILGLAQTGPLKTTVTGVEMFKKILDHGKAGDNVGLLLRGLKRGDVERGQVVCRPGYSEDCKKFEAEIYVLTKDEGGRHTAFVTNYSPQFYFRTADVTGRVELLGEMKMVLPGDNVTANFDLISPVPLEPGQRFAIREGGRTVGAGVVSKVLS
Protein: Uncharacterized protein, isoform L (M9PER0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAALQRKLVHKQFNSPMGLYSQENVKATLNRELKAFGGEGIEVDDQITKPLNLANSAVLRAVEEEEQQAKCGYKRVAWPPASEERIIREFTPQPQTQSPAPGAGGYYPQAHAPTAAAAAPPQGPIYNNVQPRTTQTPQNAYPSAPQTTSTAYPTNQYPDSYSHQEQQQQQQQQQPVQYTQAQFGRQRSREPVQVSAPSPAPATDPSGYPYQANYQSNYPQEPLQAVNNVGGGWKHIGAPQPKSRSEFTAGNGAYPPFQGSYQQQQQQPQQYGAPSYDGQQPGAQWQQQQQQQQVPQQQYQPQSQAQAPYQPPQWNQPQQQQQQPSYQASPYQQQQQQQPSYYPQQNGGSTYAQPPYNSYSQPQLPYSQDQTDLQQQQQQQQQQYPGAYAGQDSYRGASPGIITLRKEAPVSQKPAPVYTSQPAAVSYQGGSKLRGDLKWPPPEYKEAAARENEERRQLALGPVCRPRRVNRDYTPFFAKHQLNNGYPSYKVPPGTQHIFG
Protein: BEL1-like homeodomain protein 6 (BEL1-like protein 6) (O65685)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeobox protein knotted-1-like 7
- Transcription repressor OFP4
- Transcription repressor OFP1
- Transcription repressor OFP2
- Transcription repressor OFP5
- Transcription repressor
- Transcription repressor OFP10
- Transcription factor MYB46
- Protein KNATM
- NAC domain-containing protein 73
Sequence:
MENYPETQFIPGDSMIQNAIVSYSEESAGRERRTEANNVSASQERQALSRFGGVPQMQNIGQDFGSWRDQASDRNGFQLMSAMAGATGILQTGQGLSLSLGSQILPGIHQISHQNMAPRGNEYATQSFPGGNQNLDVVRTIPNSKYLKAAQQLLDEAVNVKKALKQFQAEGDKNNENPQEPNQSTQDSSTNPPADISQSERQEMQSKLTKLLSMLDEVDRRYKQYYQQMQIVVSSFDVIAGYGAAKPYTALALQTISRHFRSLRDAISGQILVLRKCLGEQQDGSDGKRVGIISRLKYVDQHLRQQRGFMQPQAWRPQRGLPENSVLILRAWLFEHFLHPYPKDSDKIMLARQTGLSRGQVSNWFINARVRLWKPMVEEIYKEEFTENDSNSSSENTPKMSEIGPVAADDEDRAREFSQDQTKPDHGHGYGEETRGMVQGSHMDGRRFMAVEPTYHVADTSRLGRGDVSLTLGLQNSQGQDNVVAMSSEAYNNFSGVDIYENAIPGDEMEYVNPGSRQNRINSSQLVHDFVA
Protein: Lysosomal enzyme trafficking factor (Transmembrane protein 251) (F1LXS7)
Organism: Rattus norvegicus (Rat)
Function: Required for mannose-6-phosphate-dependent trafficking of lysosomal enzymes. LYSET bridges GlcNAc-1-phosphate transferase (GNPTAB), to the membrane-bound transcription factor site-1 protease (MBTPS1), thus allowing proteolytic activation of the GNPTAB. GNPTAB is involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes. LYSET is thus an essential factor for maturation and delivery of lysosomal hydrolases.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:36096887}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with GNPTAB and GNPTG in Golgi apparatus cisternae. {ECO:0000250|UniProtKB:Q8N6I4}.
Interaction partners:
- PWWP domain containing 2
- Trichoplein keratin filament-binding protein
- TFIID_NTD2 domain-containing protein.
- TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
Sequence:
MPKAPDYSELSDSCTLAGGTARFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNRLALEHIQQHPEEPREGTTWTHSLKARLLSLPFWLWTVIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAIICNRHQAFVKASNQISRLQLIDT
Protein: Double-stranded DNA-binding family protein (F4I354)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Pathogenesis-related protein 1
- Small nuclear ribonucleoprotein E
- Adenylosuccinate synthetase, chloroplastic
- Prefoldin subunit 1
- Small ribosomal subunit protein eS28z/eS28y
- Prefoldin subunit 4
- Small ribosomal subunit protein eS28x
- Small nuclear ribonucleoprotein E
- DNA helicase
- Nucleic acid-binding, OB-fold-like protein
Sequence:
MQELMARQGMGKQGNQQNPEQEKQQEDAKREADERRQMMLSQVLSSQARERIARIALVKPEKARGVEDVILRAAQMGQIVEKVSEERLITLLEQINSQTTKQTKVTVSTNGAVGWTTIRKEEEYYDVLCISMEISLLC
Protein: Beta-galactosidase (EC 3.2.1.23) (D3ZUM4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Carboxypeptidase
- Alpha-galactosidase
- Lactase/phlorizin hydrolase
- N-acetylgalactosamine-6-sulfatase
- Sialidase-1
- Glucosylceramidase
- Beta-hexosaminidase subunit alpha
- N-acetylglucosamine-6-sulfatase
- Galactose mutarotase
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2
Sequence:
MFRVPLCMLLPLLALLQLLGAAHSFYNVSQRTFELDYKRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLDAIQTYVPWNFHEPQPGQYDFSGDRDVEHFIQLAHQLGLLVILRPGPYICAEWDMGGLPAWLLEKESIVLRSSDPDYLAAVDKWLAVLLPKMKRLLYQNGGPIITVQVENEYGSYFACDYNYLRFLEHRFRYHLGNDIILFTTDGAAEKLLKCGTLQDLYATVDFGTTGNITRAFLIQRNFEPKGPLINSEFYTGWLDHWGQPHSKVNTKKLVASLYNLLAYGASVNLYMFIGGTNFAYWNGANMPYAPQPTSYDYDAPLSEAGDLTEKYFAVRDVIRKFKEVPEGPIPPSTPKFAYGKVALRKFKTVTEALGILCPNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPINGVRDRAYVSVDGVPQGILDRNRMNVLNIRGKAGATLDILVENMGRVNYGNSIKDFKGLISNMTLNFTVLTNWTMFPLDTEALARSHLGNWEAADEGHLDGHSTLRSSNFTLPTFYVGNFSIPSGIPDLPQDTFIQFPGWAKGQVWINGFNLGRYWPTKGPQMTLFVPRNILTTSAPNNITVLELESSPCSNGTLELCTVEFVDTPVIG
Protein: 2'-5' oligoadenylate synthetase 1E (A0A0J9YV17)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MARELFRTPIWRLDNFIEDQLLPDTTFLTELRADIDSISAFLKERCFQGATHPMRVARVVMMKGDTASPLNPLTTTKSTPNSSMSAPPWRRRASSPSASPTFIRAS
Protein: Putative golgin subfamily A member 2B (Golgin subfamily A member 2-like protein 1) (Q9HBQ8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDSEEEEEVPQPMPSIPEDLESQKAMVAFFNSAVASAEEEQARLCGQLKECTASAWLICWPRPRRNLRQQPQPQELGVIPCVGRPTRPCRGPWRSCGRVHRTVPEPEGSAEGGGVHQQAGPGQGRGEGEAAGAGVACGRLQQVA
Protein: Translation initiation factor IF-1, chloroplastic (P0C380)
Organism: Oryza sativa subsp. japonica (Rice)
Function: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
Subcellular location: Plastid, chloroplast {ECO:0000255|HAMAP-Rule:MF_00075}.
Interaction partners:
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS19
- 40S ribosomal protein S15, putative, expressed
- 40S ribosomal protein S29, putative, expressed
- Small ribosomal subunit protein uS8c
- 40S ribosomal protein S20, putative, expressed
- 40S ribosomal protein S20, putative, expressed
- Small ribosomal subunit protein uS10c
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS12m
Sequence:
MTEKKNRREKKNPREAKITFEGLVMEALPNGMFRVRLENDTIILGYISGKIRSSSIRILMGDRVKIEVSRYDSSKGRIIYRLPHKDSKRTEDSKDTEDLKDTKDSKG
Protein: Proton myo-inositol cotransporter hmit-1.1 (H(+)-myo-inositol cotransporter hmit-1.1) (H(+)-myo-inositol symporter hmit-1.1) (Q9XXR3)
Organism: Caenorhabditis elegans
Function: H(+)-myo-inositol cotransporter (By similarity). Probably by promoting the transport of myo-inositol regulates intracellular osmosis in response to hyperosmotic stress.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21679696}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the lumenal side of intestinal cells. {ECO:0000269|PubMed:21679696}.
Interaction partners:
- ADP,ATP carrier protein
- IBR domain-containing protein
- Deoxynucleoside triphosphate triphosphohydrolase sahd-1
- Mitochondrial scaffolding protein 1
- Aquaporin-9
Sequence:
MVAVAAFSSSGQDKPAHTPKLGLFVYILAAASVIGGFLFGYDTSVVSAAMLYMPDAPGLKPMDTVWQEVLVSISPGMAAVGSLMSGTSSDYIGRRKVILGASAIFTIGALVCAASVNKIMLLVGRVLLGIAIGFASMIVPVYLGETAPTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPYNVGWRLMFAFAAVPSIIQFVCFMFLPETPRWLYENGFETETREVLEKVYNGDKEWVEYEMAEIIAFNEDQAKENEKAHASGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSGISNNHTTIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDSAATLPANQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSSTGSCTNSNGSIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCVAISTTSNWVFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEEVEMLFMNKKQRREAESRRRETVTEVRSRMNSTVSFGQHNEVHKY