wanglab/gogpt-training-data huggingface dataset:
Protein: Serine/arginine repetitive matrix protein 4 (Medulloblastoma antigen MU-MB-2.76) (Neural-specific serine/arginine repetitive splicing factor of 100 kDa) (Neural-specific SR-related protein of 100 kDa) (nSR100) (A7MD48)
Organism: Homo sapiens (Human)
Function: Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity). Promotes alternative splicing of REST transcripts to produce REST isoform 3 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells. Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system. Regulates alternative splicing events in genes with important neuronal functions (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8BKA3}.
Interaction partners:
- Polypyrimidine tract-binding protein 2
- Disheveled-associated activator of morphogenesis 1
- Serine/arginine-rich splicing factor 11
Sequence:
MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR
Protein: High mobility group protein 1.2 (Q09390)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histone H2A.V
Sequence:
MNSGYSANIFPSSSSPTLYQSHQLQPNPSATMYQATPRDMGKPPVRGKTSPYGFFVKMCYEEHKKKYPNENVQVTEISKKCSEKWKTMVDDEKRRFYELAQKDAERYQAEVSVAAYGGEDAMRKRKRAKKDPHAPKRALSAFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYKAEMQKMSGMDHYDDDNIHHVVHVEDINSQNIS
Protein: Dachshund (Q24030)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHGMPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGPLGIDAHAAVPASSTETLLRNIQSLLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNIKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN
Protein: Protein disulfide isomerase CRELD1 (EC 5.3.4.1) (Cysteine-rich with EGF-like domain protein 1) (Q96HD1)
Organism: Homo sapiens (Human)
Function: Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane (By similarity).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- ATP-dependent RNA helicase SUPV3L1, mitochondrial
Sequence:
MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
Protein: Tail tube protein (TTP) (Gene product 40) (gp40) (Gene product M) (gpM) (P79679)
Organism: Escherichia phage Mu (Bacteriophage Mu)
Function: Polymerizes to make up the central tail tube that is surrounded by the tail sheath protein (TSP). Tail tube protein polymerization takes place around the tape measure protein (TMP) and is probably directed by chaperone proteins. Upon binding to host cell, the tail sheath contracts and the tail tube penetrates the host envelope. The tail tube is involved in viral genome delivery during ejection.
Subcellular location: Virion {ECO:0000305}. Host cytoplasm {ECO:0000305}. Note=Tail. {ECO:0000305}.
Interaction partners:
Sequence:
MAGNQRQGVAFIRVNGMELESMEGASFTPSGITREEVTGSRVYGWKGKPRAAKVECKIPGGGPIGLDEIIDWENITVEFQADTGETWMLANAWQADEPKNDGGEISLVLMAKQSKRIA
Protein: CHCH domain-containing protein (Q381K8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTTSGVESVSTTVNEGLKPQTEGSEERRPTTFKELRPSWLTPFFGANEPEPYKPPERGHPCKAFSRQVHECLDRNGNNVDFCQSKLALLQSCLKELGL
Protein: Oncostatin-M (OSM) (P53347)
Organism: Mus musculus (Mouse)
Function: Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity). Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
Subcellular location: Secreted.
Interaction partners:
- Leukemia inhibitory factor receptor
- Oncostatin-M-specific receptor subunit beta
- Interleukin-6 receptor subunit beta
- Leukemia inhibitory factor
- Cardiotrophin-1
- Interleukin-11
- Interleukin-6
- Tyrosine-protein kinase JAK2
- Interleukin-27 receptor subunit alpha
- Tumor necrosis factor
Sequence:
MQTRLLRTLLSLTLSLLILSMALANRGCSNSSSQLLSQLQNQANLTGNTESLLEPYIRLQNLNTPDLRAACTQHSVAFPSEDTLRQLSKPHFLSTVYTTLDRVLYQLDALRQKFLKTPAFPKLDSARHNILGIRNNVFCMARLLNHSLEIPEPTQTDSGASRSTTTPDVFNTKIGSCGFLWGYHRFMGSVGRVFREWDDGSTRSRRQSPLRARRKGTRRIRVRHKGTRRIRVRRKGTRRIWVRRKGSRKIRPSRSTQSPTTRA
Protein: Reproductive homeobox 8 (TOX) (Q6VSS7)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MLFFLRLNQEVKPRISRSRSTVNSIHAMEPQEVTQSSLLRDDEIKESDDAAAWIVSQEMKEREENAGIQDCPLLGAMAAEGEGENEEEGEEGEEGEEGEEGEEGEEGEEGEEGEEEEEEEEEEEEEEEEEEEEEEEEEEGEEGEEGEEGDEGGEGGEGGEEGEEEGEEEEGGEGEGEEEEEEEEEEEEEEEEEEEEEEEEEAAAAAAARDETTAGSSAPVDDRSHDAGASSNGEDRGQGEELIPGGTKGLEALPSPSGQLPRNRYRFTKFQLQELERIFERNHYPSAAARRELARWIGVTESRVENWFKSRRAKYRKCLM
Protein: Hydroxysteroid 17-beta dehydrogenase 4 (A0A2R8YDT8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKIIMTSSASGIYGNFGQANYSAAKL
Protein: Uncharacterized protein (Q384A8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVKLKDVSRKGDTQSPTTTVIGKSLGGRHEDALVRAVEKYVPDEIARHLSSLTVYAQLRAGLCPGECNGGHNNNANVGAISCSGNCKNGNAAVSCDMRRRNCGIMSGCKRDVHLESCVSRVLSCRVCHVLRGYCAFWVESMLTIRTVTSASTNFSRHKRLRRSDDVAVVADCVVSSGLDGAGGNRRYNVKLLTLHIVDNEAYKNPGNYVFVLQSVCQPGRVLQLECYPNHMIRFGLLMHFLWQCPCEAFAASQAKGGTGKEKDLRRLQVNSAFSSTDVDILPVTDFNECNSCGMSLHLSTSPAAKEVVVETQSGAVGPSVLVLGLGANVIGNWLDEALPPNVRIDVVEVEPTVLQICRDHKQVPPCDELVNEANEGTGVWCVTRGHKRYPNYRFIVGDAREVLKESNDDGRSEGRNKKCISLSYDVVFLDCYDPAKECMMHDANLVDLCRVRLRPGGALIVNAHIIPEKEMLQEQFLDRGFSSVQVLRVSSCNQSIVVCLASHSGSAGKTAEEVDGERLSGRFTVLSAGRATRYIHNIIEAGNRVYLHKPNTCYFGAGWLKSSKVLENDTCFVKLWTHVD
Protein: Uncharacterized RNA-binding protein C1861.04c (Q9USY2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- LSM complex subunit lsm4
- LSM complex subunit lsm5
- LSM2-LSM8 complex subunit lsm8
- LSM complex subunit lsm2
- LSM complex subunit lsm7
- LSM complex subunit lsm6
- LSM complex subunit lsm3
- Pre-mRNA-processing factor 31
- U6 snRNA phosphodiesterase 1
- Pre-mRNA-splicing factor brr2
Sequence:
MSQIQDLKDENVEMDIDPQEQNEKKPLLLDELTKFTILHPYNYDSHIKLIEELKRLDKKKELSEARKTFQSIFPLSEDLWVDYLLDECKNCRTLDDYVRIKTLFDLAVQDYLSIKIWCMYLEFTLNLMDTSSFEQEQSELNGVITLTDAHSLFERAYQTCKFHFSKSQCVWTLYLEFLQTFGDALFEGEEEQEIVFKNKIYDFHIDRLKLPHEQIEETFTSLSTFVTNNWSPSEYEDVMVKSNKVYETTLKRNAKIFNKELLLNSANHSLEAYMDLINDESRRSTAELQYITTLYERAIVLYPLIPELWLQYTAWLSKVDFSSSQASSVAERATRNCSWIGRIWSIKLTYMTLSGASTSAVCEEKDRCLNSNLLVNFDEVIDFFSGFLKACLYLSSNEDKPQEFLKHQIHKVEDYLRKNHKGSKDARMRIELSKIYLYSEISDFESVEKCWSDMFHDFQNQALYWISRYISTMKYNPELAAETLKKSLYKNVDQPQLLFQFYQSIMDLNNDCFTNTSHLYDVLNAQRISFKRQLDSFAEETKQTVENTEPLKVPQADDTAALSKKRKPGQEGDVFKKSKPIEQHRNREELTVLVTNLPSDISENELKIFFKDCGNIIRIFILEDNQKDVKVAQIEFSETSEVLAAKTRDLKSIRGHEISVQIHVDTNLYVTNFPPTYDELDITKLFSAYGNVVDVRFPSLRYNTNRRFCYVQMRKPDEAHNALQLHKKLLEEKYPIQVFISDPLRRTPRSGAVYEGRELYVTNIDFKVNEKDVETFFRDYGQVESVRIPKRFNQHKGFGYVVMTTNQDAENALSAAGKQLGNRVLNVVLSKPRESLEKTRVSSNDNRTLAKSFETTESNKMSTPKKSFEQIKSKSLGVTNVDGTVNEARLRSLFESYGKLYRVVLHPEHEGAVVEFLDIHDAGKASLALEGHEIGGRLLHITTVNEMMHNVPSSMNHSDYNTSATRPRRLGSRTFQGFNSNHSNINSKKDDLDDKEMQIDAPKSNDDFRKMFLK
Protein: Uncharacterized membrane protein Rv3835 (P9WKW5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: May play a role in septum formation.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Secreted {ECO:0000269|PubMed:17443846}.
Interaction partners:
- Probable conserved proline rich membrane protein
- Zinc metalloprotease
- UPF0603 protein Rv2345
- Secreted protein
- Probable membrane protein
- Conserved protein
- Serine--tRNA ligase
- Probable conserved transmembrane alanine rich protein
- Possible conserved membrane protein
- DUF6542 domain-containing protein
Sequence:
MLDAPEQDPVDPGDPASPPHGEAEQPLPGPRWPRALRASATRRALLLTALGGLLIAGLVTAIPAVGRAPERLAGYIASNPVPSTGAKINASFNRVASGDCLMWPDGTPESAAIVSCADEHRFEVAESIDMRTFPGMEYGQNAAPPSPARIQQISEEQCEAAVRRYLGTKFDPNSKFTISMLWPGDRAWRQAGERRMLCGLQSPGPNNQQLAFKGKVADIDQSKVWPAGTCLGIDATTNQPIDVPVDCAAPHAMEVSGTVNLAERFPDALPSEPEQDGFIKDACTRMTDAYLAPLKLRTTTLTLIYPTLTLPSWSAGSRVVACSIGATLGNGGWATLVNSAKGALLINGQPPVPPPDIPEERLNLPPIPLQLPTPRPAPPAQQLPSTPPGTQHLPAQQPVVTPTRPPESHAPASAAPAETQPPPPDAGAPPATQSPEATPPGPAEPAPAG
Protein: ABC transporter G family member 16 (ABC transporter ABCG.16) (AtABCG16) (Probable white-brown complex homolog protein 16) (AtWBC16) (Q9M2V7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MSRILVEDDNATPFHSMEIISSSLTLGQLLKNVSDVRKVEVGDETPVHEFFDRDGSSLDGDNDHLMRPVPFVLSFNNLTYNVSVRRKLDFHDLVPWRRTSFSKTKTLLDNISGETRDGEILAVLGASGSGKSTLIDALANRIAKGSLKGTVTLNGEALQSRMLKVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQLGIRNAAKTIIGDEGHRGISGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTSAFMVVKVLKRIAESGSIIIMSIHQPSHRVLSLLDRLIFLSRGHTVFSGSPASLPSFFAGFGNPIPENENQTEFALDLIRELEGSAGGTRGLVEFNKKWQEMKKQSNPQTLTPPASPNPNLTLKEAISASISRGKLVSGGGGGSSVINHGGGTLAVPAFANPFWIEIKTLTRRSILNSRRQPELLGMRLATVIVTGFILATVFWRLDNSPKGVQERLGFFAFAMSTMFYTCADALPVFLQERYIFMRETAYNAYRRSSYVLSHAIVTFPSLIFLSLAFAVTTFWAVGLEGGLMGFLFYCLIILASFWSGSSFVTFLSGVVPHVMLGYTIVVAILAYFLLFSGFFINRDRIPQYWIWFHYLSLVKYPYEAVLQNEFSDPTECFVRGVQLFDNSPLGELTYGMKLRLLDSVSRSIGMRISSSTCLTTGADVLKQQGVTQLSKWNCLLITVGFGFLFRILFYLCLLLGSKNKRR
Protein: C4-type zinc ribbon domain-containing protein (O51655)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Interaction partners:
- RNA polymerase sigma factor RpoD
- Uncharacterized protein
- Ribonuclease H1 N-terminal domain-containing protein
Sequence:
MENNIDTLKKLEVIYKSKFELEERRKSIPKYLEAKKNQIEELSKVLVDLQQKFKEYQKEDSALKLDIQDINSRKSKAEEKIDSIKTQREYEALEKELQVIIDDEVTIRKKMTHVNGLKTKIEKEILDVNEKHIKEEECFRAESSSFELELLEIEKKLLEIESEELNCASKMNEDFLFKFQRIIRNKSNGVVPLVNNVCKGCHMILPIEFANKVRREPNDIKFCPYCSRILYYQDKVQISDEIIPGSLADLVE
Protein: Protrudin (Zinc finger FYVE domain-containing protein 27) (Q3TXX3)
Organism: Mus musculus (Mouse)
Function: Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (By similarity). Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections (By similarity). Acts as an adapter protein that facilitates the interaction of KIF5A with VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 and the ZFYVE27-KIF5A complex contributes to the transport of these proteins in neurons. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a KIF5A/B-dependent manner.
Subcellular location: Recycling endosome membrane {ECO:0000305|PubMed:17082457}; Multi-pass membrane protein {ECO:0000305|PubMed:17082457}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24668814}; Multi-pass membrane protein {ECO:0000269|PubMed:24668814}. Cell projection, growth cone membrane {ECO:0000269|PubMed:17082457}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes at both dendrites and axons (PubMed:17082457). Localizes to endoplasmic reticulum tubular network. {ECO:0000269|PubMed:17082457, ECO:0000269|PubMed:24668814}.
Interaction partners:
- Ras-related protein Rab-11A
- Vesicle-associated membrane protein-associated protein A
- PDZ domain-containing protein 8
- FYVE and coiled-coil domain-containing protein 1
- StAR-related lipid transfer protein 3
- Receptor expression-enhancing protein 1
- Spastin
- Atlastin-1
- Vesicle-associated membrane protein-associated protein B
- Oxysterol-binding protein-related protein 1
Sequence:
MQTSDRDLSGPEASPSGMPEVLSECPPAPTKSAAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNILFLTLNEGAWYSMGALMISVPALLGYLQEVCRGQLPESELMRRKYHSIRQEDLQRVRLSRVHLSRPEAVAEVKSFLIQLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGDFFRVVCEYRACLQRRMNPRQEECACESSALQGAGGRGLLDSSPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLEDEEGTPCPAEDELTLQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPRSSMGATAPEAQRETVCVCASCNQTLSK
Protein: Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1) (O14490)
Organism: Homo sapiens (Human)
Function: Part of the postsynaptic scaffold in neuronal cells.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Postsynaptic density {ECO:0000250}. Synapse {ECO:0000250}.
Interaction partners:
- Disks large homolog 4
- SH3 and multiple ankyrin repeat domains protein 3
- SH3 and multiple ankyrin repeat domains protein 1
- Homer protein homolog 1
- SH3 and multiple ankyrin repeat domains protein 2
- Disks large homolog 1
- Homer protein homolog 3
- Metabotropic glutamate receptor 1
- Neuroligin-1
- Metabotropic glutamate receptor 5
Sequence:
MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGPFSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGYHTLQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQAARYGKRSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSASQYFLEAYNTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL
Protein: Ranshi (Q9VHM4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein mago nashi
- RNA-binding protein 8A
- Serine/arginine repetitive matrix protein 1
- Partner of Y14 and mago
Sequence:
MEGKVCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKADTIFDKP
Protein: PvdN (G3XCY5)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- PvdO
- Probable dipeptidase
- Acyl-homoserine lactone acylase PvdQ
- PvdP
- L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH
- L-ornithine N
- Pyoverdine export membrane fusion protein PvdR
- Pyoverdine export outer membrane protein OpmQ
- PvdG
- Probable thioesterase
Sequence:
MNDRRTFLKQAGILAAGLPLLSAAQSLRAEGVPSDAGNKWKALRQQFDLDPQYLHFANFLLTSHPRPVREAIERLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGTGVIIARSEQLQEHLVPSIPTFSRADNFGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNAYLKQRLGEHPKVRLVTPTSPELSSGFTFFRVEGRDCEAVAKHLMAHRVISDAVDRDVGPVVRLAPSLLNDEAEIDRVLEILAPQLA
Protein: Factor in the germline alpha (FIGalpha) (Class C basic helix-loop-helix protein 8) (bHLHc8) (Folliculogenesis-specific basic helix-loop-helix protein) (Transcription factor FIGa) (Q6QHK4)
Organism: Homo sapiens (Human)
Function: Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeobox protein NOBOX
- LIM/homeobox protein Lhx8
- Bone morphogenetic protein 15
- Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
- Forkhead box protein L2
- Y-box-binding protein 2
- Protein POF1B
- Growth/differentiation factor 9
- Zona pellucida sperm-binding protein 4
- Zona pellucida sperm-binding protein 1
Sequence:
MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCRLKRLPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAFGLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV
Protein: LIM homeobox 2 (LIM homeobox protein 2) (LIM/homeobox protein Lhx2) (C4TJC6)
Organism: Sus scrofa (Pig)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- LIM domain binding 1
- SIX homeobox 3
- Forkhead box protein G1
Sequence:
MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTEAALQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
Protein: Clasp1 protein (Q5M928)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}.
Interaction partners:
Sequence:
LTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERITKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
Protein: Serine/threonine-protein phosphatase PP1-2 (EC 3.1.3.16) (P32598)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in control of glycogen metabolism, meiosis, translation, chromosome segregation, cell polarity and G2/M cell cycle progression. PP1 may act in opposition to the IPL1 protein kinase in regulating chromosome segregation by dephosphorylating H3S10ph. The BUD14-GLC7 complex is necessary to regulate microtubule dynamics at the cortex and may function as a specific activator of the dynein complex.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12819204}. Nucleus {ECO:0000269|PubMed:12819204}.
Interaction partners:
- Protein MPE1
- Protein phosphatase 1 regulatory subunit SDS22
- Endoribonuclease YSH1
- Cleavage factor two protein 2
- RNA end formation protein 2
- Protein CFT1
- Protein SYC1
- COMPASS component SWD2
- Protein PTI1
- Serine/threonine-protein phosphatase 1 regulatory subunit GAC1
Sequence:
MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKSLPRQAGGRKKK
Protein: Zinc finger protein 950 (Q8BL88)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDAVTYDEVHVNFTQEEWALLDHSQKSLYRDVMLETYKNLTAIGYNWDDHNIEEHCQSSRRHGR
Protein: Adenosine receptor A1 (Q4VQ11)
Organism: Sus scrofa (Pig)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU201114}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU201114}.
Interaction partners:
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVTCPVLILTQSSILAMLAIAVDRYLRVKIPLRYKTVVTPRRAAMAIAGCWVLSFLVGLTPLFGWNNLSEVEQDWVANGSVGEPLIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPPKYYGKELKIAKSLALILFLFALTWLPLHILNCIALFCPSCHKSSILIYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDGDPPEERPDD
Protein: Wee1-like protein kinase 2 (Wee1-like protein kinase 1B) (Wee1B kinase) (H7C5P0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
VYKCIKRLDGCVYAIKRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMIIQNEYCNGGSLQAAISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFICHKMQSESSGVIEEVENEADWFLSANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQENMIQPDAEQRPSAAALARNTV