wanglab/gogpt-training-data huggingface dataset:
Protein: Protein SAR DEFICIENT 1 (Q9C9T2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that binds DNA in a sequence-specific manner, 5'-GAAATTTTGG-3', to promote the expression of target genes. Recruited to the promoter of ICS1 and other defense-related genes (e.g. PR1 and SID2) in response to both biotic (e.g. Pseudomonas syringae pv. maculicola ES4326) and abiotic stresses (e.g. UV-B), thus triggering slow defense responses by stimulating salicylic acid (SA) biosynthesis. Required for basal and systemic acquired resistance to P. syringae pv. maculicola and Hyaloperonospora arabidopsidis.
Subcellular location: Nucleus {ECO:0000269|PubMed:20921422}.
Interaction partners:
- Isochorismate synthase 1, chloroplastic
- Lipase-like PAD4
- Calmodulin-binding transcription activator 3
- WRKY transcription factor 28
- Protein EDS1
- Probable flavin-containing monooxygenase 1
- Probable WRKY transcription factor 70
- 4-substituted benzoates-glutamate ligase GH3.12
- Regulatory protein NPR3
- Probable WRKY transcription factor 46
Sequence:
MAGKRLFQDLDSDQENKSEKRIKSVLPSLASPISSVFGALISENTLRSVLEPVIRKVVRQEVEYGISKRFRLSRSSSFRIEAPEATTPTLKLIFRKNLMTPIFTGSKISDVDNNPLEIILVDDSNKPVNLNRPIKLDIVALHGDFPSGDKWTSDEFESNIIKERDGKRPLLAGEVSVTVRNGVATIGEIVFTDNSSWIRSRKFRIGAKVAKGSSGQGVVVCEAMTEAIVVRDHRGELYKKHHPPMLEDEVWRLEKIGKDGAFHKKLSSRHINTVQDFLKLSVVDVDELRQILGPGMSDRKWEVTLKHARECILGNKLYISRGPNFFMILNPICEVMKALIDGHVLSSQESLNQPYVKNLVRDAYSKGNFLEVGERTANEAALLTQGDDLDQQYAASHYQNIEIDKSYQQNGYVQERSTNNLEIVNEGYITTPAEFNICFTGSSSQNHINPF
Protein: Flagellin (P04949)
Organism: Escherichia coli (strain K12)
Function: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Subcellular location: Secreted. Bacterial flagellum.
Interaction partners:
- Flagellar hook-associated protein 1
- Flagellar secretion chaperone FliS
- Flagellar hook-associated protein 2
- Flagellar hook-associated protein 3
- Flagellar hook protein FlgE
- Flagellar basal body rod protein FlgB
- RNA polymerase sigma factor FliA
- Basal-body rod modification protein FlgD
- Flagellar motor switch protein FliM
- Flagellar basal-body rod protein FlgC
Sequence:
MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRVRELTVQATTGTNSESDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKNGSMKIQVGANDNQTITIDLKQIDAKTLGLDGFSVKNNDTVTTSAPVTAFGATTTNNIKLTGITLSTEAATDTGGTNPASIEGVYTDNGNDYYAKITGGDNDGKYYAVTVANDGTVTMATGATANATVTDANTTKATTITSGGTPVQIDNTAGSATANLGAVSLVKLQDSKGNDTDTYALKDTNGNLYAADVNETTGAVSVKTITYTDSSGAASSPTAVKLGGDDGKTEVVDIDGKTYDSADLNGGNLQTGLTAGGEALTAVANGKTTDPLKALDDAIASVDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG
Protein: Cytospin-A (A0A494C1J1)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186, ECO:0000256|RuleBase:RU367063}. Cytoplasm, cytoskeleton {ECO:0000256|RuleBase:RU367063}. Cell junction, gap junction {ECO:0000256|RuleBase:RU367063}.
Interaction partners:
Sequence:
MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKGLTLLPRLEYGGVITAQCSFDLPGSSDPLTSTFPITRTTGMCHFAQTKSSDDLLAGMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPGNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET
Protein: Protocadherin gamma A2 (Protocadherin gamma subfamily A, 2) (Q91XY6)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MATLQKLPQSRMLVLLCALWAALWEAKAGQIRYSVPEEIDKGSFVGSIAKDLGLEPQALEERGVRIVSRGKSQLFALNPRSGSLVTAGRIDREELCAQSTPCLVNFNLLLEDKLTIYSVEVEVTDVNDNAPRFGVEDPELKISETTTPGFRIPLKSAHDADVGENTLQKYKLNSNDHFSLDVRTGADGNKYPELVLERALDREEEAVHHLVLVASDGGNPVRSGTCRIRVKVLDANDNAPAFTQAEYRVRVPENTPVGTRILTVTATDADEGYNAQVTYFQEHDPGETTDAFELKSTSGDITITKSLDYEKAKFHEIDIEAQDGPGLLTRTKVIVTVLDVNDNAPEFYMTSATASVPEDAPLGTVIALFNVHDRDSGQNAVVTCSLPEMLPFKLERSVDSYYRLVTTRALDREQFSFYNITVSAKDGGSPSLSTDAHLLLQVADINDNPPSFPRRVYSAYIPENNPRGTSIFSVLASDPDSNDNAHVTYSLAEDSFQGAPLSSYVSINSDTGVLYALRSFDYEQFQDLQLWVIAADSGNPPLSSNVSLSLFLVDQNDNTPEILYPALPTDGSTGVELAPRSADPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTIAIADNIPEVLADLGSIRTPANPDDSELTLYLVVAVAVVSCVFLAFVIALLALRLRRWHLSRMLQASRDGLGGIPASHFVGVDGVRAFLQTYSHEVSLTADSGKSHIIFPQPNYADTLISQESCEKTDFLSAPQSLLDDKREETPQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Protein: Coronin-7 (K8ESK9)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- NADPH--cytochrome P450 reductase
Sequence:
MAWRFAASKFKNTTPKVPKKENEYDDGDEASVEEDHYDDLTSESNNGVGSRRRSRAVSCKIKFNTETIFDVPVGNLSCTNDGIHASADFLAFHIEGEGGKLGVLPITAKGRRTRNDIGIIAAHGEQVADFGFLTFADELLATCSRDEPVKIWKLSRDHSPKLATEIDVGGGNVIAECLRAHSTADNILAVGSHGSTYITDISTGKTAVELSGVTDKVQSMDWSEDGKLLAVSGDKGRQIVVYDPRASMEPIQTLEGHGGMGREARVLFAGNRLISTGFTTKRIQEVRAYDTGKWGAPVHTQEFVSTTGVLIPHYDADTRLVFLSGKGTNKLFMLEMQDRQPYLSHVFELTLPEQTLGATIGAKRRVHVMDGEVDTYYQLTKSSIVPTPCIVPRRSYRDFHSDLFPETRGAEPGCTAGEWLNGTNAVPQKVSMAPSQSSSSPPPPEPVPTPKVAQTPAPVPVPTPAAAPRPMSNNNSSSNNVPSVQEQHSVPKKEEVRELDYRPYEKENGVHTPNAETNSTQGNSSPISTISPEPVTIVKPASTPATDSVSTPSVVGPAFGKKVPEQPPVNFRKPIGASNRVPLSQRVRPKSCVVGQITSKFRHVDGQQGTKSGAVFSNLRNVNTRLPPESNGVCCSNKFAAVPLAGLGVIGIYDVNEPGKLPDGVMDGIFNKTLVTDLHWNPFDDEQLAVGTDCGQINLWRLTTNDGPRNEMEPEKIIKIGGEKITSLRWHPLASDLLAVALSNSTIELWDVANAKLYSRFVNHTGGILGIAWSADGRRIASVGKDATLFVHEPASREQRVYERKTVVESTRAARVLFACDDRIVIVVGMTKSSQRQVQMYDAQTVDLRHIYTQVIDSATQPLVPHYDYDSNVLFLSGKGDRFVNMFEVIYDSPYLLPLAPFMSPVGSQGIAFHQKLKCNVMAVEFQVCWRLSDKNLEKITFRVPRIKKDVFQDDLFPDSLVTWEPVTTGTKWMLGEQAAPVFRSLKPDGVFSSIPRAITASVRHSEMPSSSSTTNSAAQTPSTSVTHSTTEKHHHHQHHQHQEPTSVPTPSSRNMQSCGVESTQQPDRKQVSIQYSEEEGSEYFTDELDDVDDEIDDAAAAARAAENIRIPACLLQTAAQKSEEEDEYDVMETYL
Protein: High affinity heme transporter (Q92340)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: High affinity heme transporter involved in the assimilation of exogenous heme during conditions of low cellular iron.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25733668, ECO:0000269|PubMed:28193844}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:28193844}. Vacuole membrane {ECO:0000269|PubMed:28193844}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:28193844}. Note=Localizes from the cell membrane to the vacuolar membrane in the presence of heme. {ECO:0000269|PubMed:28193844}.
Interaction partners:
- Putative uncharacterized protein SPCC794.16.
- Putative uncharacterized protein C32H8.15
- UPF0494 membrane protein SPAC212.01c
Sequence:
MISLKIYFVLIFLFLKGINSAYVSNEEGETVDFTFSGFYANLTYPNEISELNYVEGNYLSTRIVRFNGSFYCDTTILSETNNVTGSCYVANCANDTVLEICDSGKEVHFTDMSGTTWSADTFTENLYWFCGGDGNKPNMTTAAAMNSDIDSYYVYGNWTIDTADSTVADYTCNYTHFQEAGDIEKGDVYTASADSSDSSSASSTIFKPSYFISCLLSVGLYLVLNF
Protein: Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (GT1) (P17809)
Organism: Mus musculus (Mouse)
Function: Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (By similarity). Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (By similarity). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:17320047, ECO:0000269|PubMed:30197081, ECO:0000269|PubMed:35810171}; Multi-pass membrane protein {ECO:0000255}. Photoreceptor inner segment {ECO:0000269|PubMed:25957687}.
Interaction partners:
- Cellular tumor antigen p53
- Solute carrier family 2, facilitated glucose transporter member 4
- Solute carrier family 2, facilitated glucose transporter member 2
- Basigin
- Hypoxia-inducible factor 1-alpha
- L-lactate dehydrogenase A chain
- Zinc finger and BTB domain-containing protein 24
- Neutral amino acid transporter B
- Large neutral amino acids transporter small subunit 1
- Hexokinase-2
Sequence:
MDPSSKKVTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGEPIPSTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVAAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLERLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
Protein: Non-histone chromosomal protein 6A (P11632)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex. Required for transcriptional initiation fidelity of some but not all tRNA genes. Seems to be functionally redundant with NHP6B.
Subcellular location: Nucleus. Chromosome. Note=Colocalizes with both RNA polymerase II and some regions that are not transcribed on chromatin.
Interaction partners:
- Histone H2A.Z
- FACT complex subunit SPT16
- FACT complex subunit POB3
- Actin-like protein ARP9
- Actin-related protein 7
- ARS-binding factor 2
- Histone H3
- Non-histone chromosomal protein 6B
- High mobility group protein 1
- Histone H2B.1
Sequence:
MVTPREPKKRTTRKKKDPNAPKRALSAYMFFANENRDIVRSENPDITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRYESEKELYNATLA
Protein: P2X purinoceptor 5 (P2X5) (ATP receptor) (Purinergic receptor) (P51578)
Organism: Rattus norvegicus (Rat)
Function: Receptor for ATP that acts as a ligand-gated ion channel.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q93086}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P56373}.
Interaction partners:
- P2X purinoceptor 2
- P2X purinoceptor 3
- P2X purinoceptor 4
- P2X purinoceptor 1
- P2X purinoceptor 6
- Glutamate receptor ionotropic, NMDA 2D
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2C
- Glutamate receptor ionotropic, NMDA 2A
Sequence:
MGQAAWKGFVLSLFDYKTAKFVVAKSKKVGLLYRVLQLIILLYLLIWVFLIKKSYQDIDTSLQSAVVTKVKGVAYTNTTMLGERLWDVADFVIPSQGENVFFVVTNLIVTPNQRQGICAEREGIPDGECSEDDDCHAGESVVAGHGLKTGRCLRVGNSTRGTCEIFAWCPVETKSMPTDPLLKDAESFTIFIKNFIRFPKFNFSKANVLETDNKHFLKTCHFSSTNLYCPIFRLGSIVRWAGADFQDIALKGGVIGIYIEWDCDLDKAASKCNPHYYFNRLDNKHTHSISSGYNFRFARYYRDPNGVEFRDLMKAYGIRFDVIVNGKAGKFSIIPTVINIGSGLALMGAGAFFCDLVLIYLIRKSEFYRDKKFEKVRGQKEDANVEVEANEMEQERPEDEPLERVRQDEQSQELAQSGRKQNSNCQVLLEPARFGLRENAIVNVKQSQILHPVKT
Protein: PSP1 C-terminal domain-containing protein (Q389H8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSAKLQPILESADANAPFDVPVTPIKSFSTNTIIGTEAGIRPTDGHSECRISVTAAEYGGKSHDRMVGSDSDITSAASSSGSHTGNNFHCYTNEGSGEGGGGARKLAPHLQSYEENTPTEASTAAGASPTPKGGNSDAEESSHGFRVPSCEPPSQRELSVAMDSHSGIQHKHENLLSPHDSSDFSGDDVSHRRCEEADDMQPNQGNQGKANGTGEMRGTRQNKGRPANVLRLPPTTKPSFVQVGTVRDHNLTVAIKQRVSHHAAVCARVNAVPRKMCLSSILPSFGTAMEMHSCKRQNMLFPSSTHVLPSCLPAVGKNGGCGYCSSTFAAPEDIEMRVKRGNDVDCTLHSVGGKLPTQSPMMSLSSSHLEKEPVSVCRVDNDKLDEEEELGFVVIVKGKHQCKGYLTGQSNLSAGAVVIVEGDRGEDIGTIQQVYAIEDVDQLLHMKVKMTDAAEEAGGCSSTVDDTTTGASDTPHEEAVLDSCSVARSDAQPPDDGMRLPRVLRLATSEDIAQLSALRDEETELLPNVLRVVNGFISKSTSAAGVTLVDIEFQFDKKKLTIYLRRPTETGFVNFRRMQRRFHRLLKCRIWLAYMDEVERQVEAYIEKAPLGCEVKDREPSRDRCLGAGDLIVV
Protein: Glycine-rich RNA-binding protein 4, mitochondrial (AtGR-RBP4) (AtRBG4) (Glycine-rich protein 4) (AtGRP4) (Mitochondrial RNA-binding protein 1b) (At-mRBP1b) (Small RNA binding protein 4) (AtSRBP4) (Q9LIS2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possibly has a role in RNA transcription or processing during stress. Binds sequence non-specifically to RNAs and DNAs. Mediates cell-to-cell trafficking of RNA interference (RNAi) signals (small RNAs (sRNA), e.g. small interfering RNA (siRNA) and microRNA (miRNA)) which regulate growth and development, as well as responses to environmental inputs, including pathogen attack; can compromise zucchini yellow mosaic virus (ZYMV) and tobacco rattle virus (TRV) infections at the early stage.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11972043}. Secreted {ECO:0000269|PubMed:31812689}. Note=Observed in the phloem translocation stream. {ECO:0000269|PubMed:31812689}.
Interaction partners:
- Glycine-rich protein like
- Large ribosomal subunit protein uL5y/uL5x/uL5w
- Homeobox-leucine zipper protein ATHB-54
- High mobility group B protein 7
- At1g16880
Sequence:
MAFCNKLSGILRQGVSQSSNGPVTSMLGSLRYMSSKLFVGGLSWGTDDSSLKQAFTSFGEVTEATVIADRETGRSRGFGFVSFSCEDSANNAIKEMDGKELNGRQIRVNLATERSSAPRSSFGGGGGYGGGGGGGY
Protein: Endolysin (EC 3.2.1.17) (Beta-1,4-N-acetylmuramidase) (Lysozyme) (Lytic enzyme) (Muramidase) (Protein P15) (P13559)
Organism: Enterobacteria phage PRD1 (Bacteriophage PRD1)
Function: Endolysin involved in host peptidoglycan digestion after permeabilization of the cytoplasmic membrane by holin. Involved in host cell lysis and liberation of progeny phages. Displays strong lytic activity against chloroform-treated Gram-negative cells.
Subcellular location: Virion membrane {ECO:0000269|PubMed:11741849}; Peripheral membrane protein {ECO:0000269|PubMed:11741849}. Note=May be associated with the viral membrane via P20 and P22. {ECO:0000269|PubMed:11741849}.
Interaction partners:
Sequence:
MQYTLWDIISRVESNGNLKALRFEPEYYQRRMERGDWDNSIIQNIRAANKCSLGTARMIYCSSWGAVQIMGFNLYLNGAFNLSVAHFMENEAYQVNEFRRFLLKNGLTEYTPERLASDKAARVKFAKVYNGAESYADLILQACQFYGVK
Protein: Interleukin 12 receptor subunit beta 1 (E9PSU7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Interleukin-23 receptor
- Interleukin-12 receptor subunit beta-2
- Interleukin-12 subunit beta
- Interleukin-23 subunit alpha
- Tyrosine-protein kinase
- Tyrosine-protein kinase JAK2
- Interleukin-12 subunit alpha
- Signal transducer and activator of transcription 1
- Tyrosine-protein kinase
- Signal transducer and activator of transcription 3
Sequence:
MDMTGLPGTSKHIIFLLLCQLSASSRGDSCCVEKISYPDEASGPSLGPRDLSCYRVSGTDYECSWQYDGPEDNVAHFLWCCFAHPNPTHTSFGQECCCYFSSGRSRTVQFWEQDGISTLSKVNFWVESRLGNRTLKSQEISQYLYNWTKLTPPLGHIRVSRSRGELRMDWNVSDGAGAEVQLRRRMPTTNWTLGDCGPQVSSGLGVIGDIHGSSSESCLCPSENMAQEIQIRRRRRLSSGAPGGPWSNWSMSVCVPPEFLPQAEIKFLVEPLNQDGRRRLTMEGQTPQLAVPEGCRDRPGAQVKKHLVLVHMLACRCQARTWKTVPLGKTLDLSGAAYDLDVLAQTRFGRSIIQKWPLPAQELTETRTLNVIVEGNVTSMQWAAQPPGTAYCLEWQPWGQDRNHTDCTLIAPEEEDPAKMVTHTWSSKPTLDQEECYRITVFASKNPKNPMMWATVLSSYYFGGNVSRVGTPRHVSVRNHTEDSVSVEWTASQLSTCPGVLTQYVVRCEAEDGTWESELLVPPTKTQVTLNSLRSRVVYKVQVRADTAMLPGSWSRPQRFSVEVQISRLSIVFASLGSFASVLLVGSLGYIGLNRAAWHLCPPLPTPCGSTAVEFPGSQDKQAWQWRNPEDFPEVLYPRDALVVEMPRDRDDETESPQATPERALDTRWPLGTEGQVQGLSEARLPDLAREDCPRGDLAHVTLPLLLGDVTQGASVLGDLWWIHKTVEPGPPTLGQEA
Protein: ASXL transcriptional regulator 2 (E7EWD6)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEISGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSSDGGSNKEGKKSRWKRKVSSSSPQSGCPSPTIPAGKVISPSQKHSKKALKQALKQQQQKKQQQQCRPSISISSNQHLSLKTVKAASDSVPAKPATWEGKQSDGQTGSPQNSNSSFSSSVKVENTLLGLGKKSFQRSERLHTRQMKRTKCADIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPSDPKVKKTPAEQPKSMPVSEASLIRIVPVVSQSECKEEALQMSSPGRKEECESQGEVQPNFSTSSEPLLSSALNTHELSSILPIKCPKDEDLLEQKPVTSAEQESEKNHLTTASNYNKSESQESLVTSPSKPKSPGVEKPIVKPTAGAGPQETNMKEPLATLVDQSPESLKRKSSLTQEEAPVSWEKRPRVTENRQHQQPFQVSPQPFLNRGDRIQVRKVPPLKIPVSRISPMPFHPSQVSPRARFPVSITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPGPGGGQGPGEGGEGQTARGGSPGSDRVSETGKGPTLELAGTGSRGGTRELLPCGPETQPQSETKTTPSQAQPHSVSGAQLQQTPPVPPTPAVSGACTSVPSPAHIEKLDNEKLNPTRATATVASVSHPQGPSSCRQEKAPSPTGPALISGASPVHCAADGTVELKAGPSKNIPNPSASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQVSATTAPAGSAPPSSTLPAASSLKTPGTSLNMNGPTLRPTSSIPANNPLVTQLLQGKDVPMEQILPKPLTKVEMKTVPLTAKEERGMGALIATNTTENSTREEVNERQSHPATQQQLGKTLQSKQLPQVPRPLQLFSAKELRDSSIDTHQYHEGLSKATQDQILQTLIQRVRRQNLLSVVPPSQFNFAHSGFQLEDISTSQRFMLGFAGRRTSKPAMAGHYLLNISTYGRGSESFRRTHSVNPEDRFCLSSPTEALKMGYTDCKNATGESSSSKEDDTDEESTGDEQESVTVKEEPQVSQSAGKGDTSSGPHSRETLSTSDCLASKNVKAEIPLNEQTTLSKENYLFTRGQTFDEKTLARDLIQAAQKQMAHAVRGKAIRSSPELFSSTVLPLPADSPTHQPLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSAVPGSQVSSNVGDVMSFSVTVTTIPASQAMNPSSHGQTIPVQAFSEENSIEGTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR
Protein: Protein UL84 (F5HB40)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Plays an essential role in viral DNA replication. May participate in the DNA replication initiation by interacting with the origin of lytic replication, oriLyt and subsequently recruiting other viral/cellular factors. Additionally, interacts with and shuttles IRS1 viral mRNA from the host nucleus to the cytoplasm (By similarity).
Subcellular location: Host nucleus {ECO:0000250}. Host cytoplasm {ECO:0000250}. Note=Shuttles between host nucleus and cytoplasm. In the nucleus, colocalizes with UL44 and IE2 in the viral DNA replication compartments (By similarity). {ECO:0000250}.
Interaction partners:
Sequence:
MPRVDPNLRNRARRPRARRGGGGGVGSNSSRHSGKCRRQRRALSTPPLTFLATTTTTTMMGVASTDDDSLLLKTPDELDKHSGSPQTILTLTDKHDIRQPRVHRGTYHLIQLHLDLRPEELRDPFQILLSTPLQLGEANGESQTAPATSQEEETAASHEPEKKKEKEEKKEEEDEDDRNDDRERGILCVVSNEDSDVRPAFSLFPARPGCHILRSVIDQQLTRMAIVRLSLNLFALRIITPLLKRLPLRRKAAHHTALHDCLALHLPELTFEPTLDINNVTENAASVADTAESTDADLTPTLTVRVRHALCWHRVEGGISGPRGLTSRISARLSETTAKTLGPSVFGRLELDPNESPPDLTLSSLTLYQDGILRFNVTCDRTEAPADPVAFRLRLRRETVRRPFFSDAPLPYFVPPRSGAADEGLEVRVPYELTLKNSHTLRIYRRFYGPYLGVFVPHNRQGLKMPVTVWLPRSWLELTVLVSDENGATFPRDALLGRLYFISSKHTLNRGCLSAMTHQVKSTLHSRSTSHSPSQQQLSVLGASIALEDLLPMRLASPETEPQDCKLTENTTEKTSPVTLAMVCGDL
Protein: GM14815p (Q961E0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MCCKIRPFTRFGTWGWTFFRIHFAQNSVVQKRTVDGLLTLIEKERQGSTVDRGLLKSLVRMLCDLQIYTSSFEEKFLDATNQLYKAESQRKMQELEVPEYLQHVNKRLAEENERLRHYLDSSTKHPLIYNVEKELLAEHLTSILQKGLDSLLEDNRLSDLTLLYGLLSRVKNGTSELCGNFNGFIKKKGRTIVIDPEKDKSMVQDLLDFKDKMDVIVRTCFEHNEKFTNSLREAFEFFINQRANKPAELIAKYVDMKLRSGNKGTTDEELEKTLDKIMVLFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDSEKSMLSKLKQECGGGFTSKLEGMFKDMELSRDINIAFRGHALSNNRDVHNLDLCVSILTMGYWPTYAPTEVTMPPQFINPQQIFNKFYLEKHSGRKLQWQPTLGNCMLRAQFDAGPKELLVSLFQALVLLLFNDKPVLSYEEILAATLIEDGELRRTLQSLACGRARVITKTPKGREILDGDQFDFNNEFTNKLFRIKINQIQMKETNEEQKATEERVFQDRQYQIDAAIVRIMKMRKTLSHNLLITELFNQLTFPVKPADLKKRIESLIDRDYMERDKDNQNQYNYVA
Protein: RE12383p (Su(Var)2-HP2, isoform B) (A1Z9S5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEDIEYLDEYKDLVLPGIKSSAPTASSAGVPRQRRISSDSSNSSSIDADIFQKLFHGKYLDDELLKEGSGSKSQDRRRRPPSPSSSDESNDALEALFCGKSSQSKLSKRRERYESFDSVDDLGEALMRPSHRLTVPKPSTSQAGSKKSQDAAPHRSISNSSSSNIAMSSGQTYACPKNKKTNSVANKTAVSANGDKWASGKNKTVTIVKPQKTDLRPSRLEPKTDPLNLGDLYGDSDSDSSYEYESDFYGDQDSDEEDEPVIDISTDTSRTTSVAEAAKRKQRQDVEKSLTGKKEQVKPARRRQLAEVEERPSLKRSKTESEAKSTVQGKYISIIGNETIMSSTTAPIRETNREAASTSPSARKSAVQEAKHVETTKHIILGPPGKKLLHSDSPAAEVKKPMVQTLLSSTLSLQKPSTLDDGSPLKIRKSLKKSIADENIDGDQSIFSSSSVLNKNTSVVAPRKVNISVSLLQSKDTQVETAASSSETPILTKKEKLKTQKSTKKPEGNKKTESKKKSLVQGPQMKTQKSEEAVSGPKILNKYLKSETESSRKTVSTVTGRKQIGQLEVLKKPESRKSEESLVEAISRKKQSQVQRLSKIDGRKSEGTSLPQPDVSKSETALKAALPKETEFPVQDAEIEKMSKGRGHQNAVKNTKTEQPKSKPKTEVRSLQAEAATELMDSMDSQSDVSDIRATFPESQGIFNVPGHMTRAISSNRSLAPTPTPMSDSQRNASKERFTPVSDQKKPIRESQTLSKRRARGGRNQPLVSKRKAGEAEDGTAVINPKRPREMDEEDHPQQNDHVQESAFAAFPVKITAASSVIPQVVRSTGNTVPQNISPRKLCVKINRRPYNKWLRSTQERNEEQEGSRNVTSLPLLGETSETDSAAESMSESILQSQVQSEPAIQPLPASQPDSCTLQASDLRIRESSAQLAPIAAYDSPAANDSSTSPALDIAPESAQTAKATLNTALCPSTEKHLPDEPTLLESSKKVAEPQKLQTFQAKCLPVPIPEVKSEPEDIMDEHSPNEPMPMVAAAPATPQPHAITEDAGPDTIQVNTLGVSTSSRPLELHSIPSASDPDGNPNAIGQTKMYSFLYPKRYKQSYDDVGLDFCCPNLDGPMRAIDFTRLHSKAEVPVLEIPQFLVITTKFISKADKNMPSKVRAKLELLDKSKERDSSKLTPTATTPTADPTGPSSFSPAPASVGPATQPFPSIIQNLLSAPLPDPGLFNHPTTVDPSTSTPVVSGSSSSTTISADLDSLSKQLPRGTKLIKKSVQQVATNPSLAGTSMVINASPSFIQLPPICPNDKQRVELQARVQMFDLVLQTLSRRAANLSVAERQRTIEEIVRTSSLMAIDVDVGTKLLENYVHYLNKATSTMTPLTPAQINSSLGASTSSTLSKSIATSDIPQQGKKISADHAQQRSSLPATIPLYDGGRNTLGFPYSCSKSTAGRKSSYVATSTPVKASTSQAAAAAALGNAQPRSTLGIPKSVREDASQFVNLNTTVCMPAPRTNAKKKPGTSGPLKSMNSSPAVQKPALCKQQTAPARTLSKSTVSSVARAKSTGSLSAVLGETPADEFVSPAGMSLSTTGNPNVFIINHAVQSEESILPDSNSSVGHMETTVIKGELDDSAEIII
Protein: Vesicle-fusing ATPase (Q9BL83)
Organism: Caenorhabditis elegans
Subcellular location: Endosome membrane {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004481}.
Interaction partners:
- Charged multivesicular body protein 1b
- Charged multivesicular body protein 6
- Charged multivesicular body protein 2a
- IST1 homolog
- Charged multivesicular body protein 5
- Charged multivesicular body protein 4b
- Charged multivesicular body protein 2b
- Charged multivesicular body protein 4b
- Charged multivesicular body protein 3
- Hepatocyte growth factor-regulated tyrosine kinase substrate
Sequence:
MSVPALQKAIELVTKATEEDTAGRYDQALRLYDQAIEYFLHAIKYESQGDKQRNAIRDKVGQYLNRAEQIKTHLKDGKTQKKPVKDGKDDSDEDEDKKKFQDKLSGAIVMEKPNVKWTDIAGLEGAKEALKEAVILPIKFPQLFTGNRKPWQGILLFGPPGTGKSYIAKAVATEAGESTFFSISSSDLMSKWLGESEKLVKNLFALAREHKPSIIFIDEIDSLCSARSDNESESARRIKTEFMVQMQGVGLNNDGILVLGATNIPWILDSAIRRRFEKRIYIPLPDIHARKEMFRIDVGKNYNTLTDQDFKVLAERCEGYSGYDISILVKDALMQPVRRVQSATHFKHVSGPSPKDPNVIAHDLLTPCSPGDPHAIAMNWLDVPGDKLANPPLSMQDISRSLASVKPTVNNTDLDRLEAFKNDFGQDGQE