wanglab/gogpt-training-data huggingface dataset:
Protein: Cytosol aminopeptidase (EC 3.4.11.1) (Cysteinylglycine-S-conjugate dipeptidase) (EC 3.4.13.23) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (LAP) (Peptidase S) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase) (P00727)
Organism: Bos taurus (Bovine)
Function: Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q68FS4}.
Interaction partners:
- Aminopeptidase N
- Glutathione hydrolase 6
- Glutathione hydrolase 7
- Glutathione hydrolase
- Glutathione hydrolase 5 proenzyme
- Glutathione synthetase
- Putative glutathione-specific gamma-glutamylcyclotransferase 2
- Gamma-glutamylcyclotransferase
- Prolyl 4-hydroxylase subunit alpha-1
- Prolyl 4-hydroxylase subunit alpha-3
Sequence:
MFLLPLPAAARVAVRHLSVKRLWAPGPAAADMTKGLVLGIYSKEKEEDEPQFTSAGENFNKLVSGKLREILNISGPPLKAGKTRTFYGLHEDFPSVVVVGLGKKTAGIDEQENWHEGKENIRAAVAAGCRQIQDLEIPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKRKVVVSAKLHGSEDQEAWQRGVLFASGQNLARRLMETPANEMTPTKFAEIVEENLKSASIKTDVFIRPKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYKGSPNASEPPLVFVGKGITFDSGGISIKAAANMDLMRADMGGAATICSAIVSAAKLDLPINIVGLAPLCENMPSGKANKPGDVVRARNGKTIQVDNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDIALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYTRQVIDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHLDIAGVMTNKDEVPYLRKGMAGRPTRTLIEFLFRFSQDSA
Protein: 5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-like protein) (TLP) (Transthyretin-related protein) (TRP) (P76341)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Subcellular location: Periplasm {ECO:0000269|Ref.3}.
Interaction partners:
- Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ
- Protein-methionine-sulfoxide reductase catalytic subunit MsrP
- Transcriptional regulatory protein HprR
- Guanine deaminase
Sequence:
MLKRYLVLSVATAAFSLPSLVNAAQQNILSVHILNQQTGKPAADVTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLESFFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS
Protein: Cyclin domain-containing protein (Q54ZC9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- SrfA-induced gene G protein
- Protein rtoA
- Dual specificity protein kinase pyk3
Sequence:
MGNCCSSSKRSNGYDSTDDRILEESLDIKGGHNNNNHGGGHHHHHHHHHHHIKRNSNGGLYNNEMKSISSENNNNNNNNNNNNNNNNNNNNNKRNSLKSSSQHKLLVDEEKEDLISASVHQKDPYDLSTSSTLTNHSSTNTLVSSGVQTTSSSSTSSIDNLLDATTTTTTTTSTTNNISSQSKNTGSHSYPHTHTRQMSTEKVGPQFKTPITSIPHHMRMEGFQRVKHNSTSSLYIKSTLSTPDNDEILRCMANALLYHIERGSQFPQKTVEIFSEEKYPITKNKIDLKSNPTVETIYKFIRDIFKAEKLDSECAIMCLAYIERIITYTGITLSSINWRRIVLSALILASKVWEDQSVWNVDFLPVFDNLTAADLNCLERQFLAMLQYNVSLNASIYAKYYFELRNFSKLDSNQFPLKPLDKSGVRRLEDHSKASEYRVKPFKRSASVDQINPPEIHTRAVIN
Protein: Nucleosome assembly protein 1-like 1 (B5X2G0)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MADMDNKDQAELDPADLEDVEDVEEEETGEDVNSKARQLTVQMMQNPQILAALQERLDGLVGSPSGYMESLPKVVKRRVNALKNLQVKCAHIEAKFYEEVHELERKYAALYQPLFDKRSDIVKAAYEPTEEECEWKADEEEELTEEMKEKAKVEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMLQEHDEPILKHLQDIKVKFSDPGQPMSFSLEFYFEPNEFFTNTLLTKTYKMRSEPDENDPFSFDGPEIMGCTGCTIDWTKGKNITLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFTPPDVPESGDLDEDSEAVLAADFEIGHFIRERIVPRAVLYFTGEAIEDDDDDYDEEGEEADDEEGEEEGEEENDPDYDPKDANPPAECKQQ
Protein: E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (Ring finger protein 115) (Zgc:158455) (A1A601)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Serine/threonine-protein phosphatase.
- Lysyl oxidase homolog 2A
- Large proline-rich protein BAG6
- Dynein axonemal heavy chain 10
- RAB41, member RAS oncogene family
- Glycerophosphodiester phosphodiesterase 1.
- Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
- GABA
- Peptidyl arginine deiminase, type II.
Sequence:
MAEAAAVPPHRFFCHCCKGEVSPKLPEYICPRCDSGFIEEVTEDSSLLDNSSNGLDDTSSQFAELWQLLFVERPFGLDLDSLDSERLPGGGSGSGGFGAGPFGGSVPGGLGGPLGGPLSGGEHWGPGRPPRLHTQRRYRSRGSSRPDRSPAVEGIVQQFLAGLFANSGVPGSPPVSWTSMLHSNPGDYAWGQGGLDAVITQLLGQFENTGPPPAEKEKISSLPTVIITQEHTDCNMECPVCKEDYTVGEPVRQLPCNHFFHSDCIVPWLELHDTCPVCRKSLNGDESGTQSSSEPSSLNTDPRTPERWSF
Protein: General transcription factor 3C polypeptide 6 (Transcription factor IIIC 35 kDa subunit) (TFIIIC 35 kDa subunit) (TFIIIC35) (Transcription factor IIIC subunit 6) (Q969F1)
Organism: Homo sapiens (Human)
Function: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.
Subcellular location: Nucleus {ECO:0000269|PubMed:17409385}.
Interaction partners:
- General transcription factor 3C polypeptide 5
- General transcription factor 3C polypeptide 4
- General transcription factor 3C polypeptide 1
- General transcription factor 3C polypeptide 3
- General transcription factor 3C polypeptide 2
- Transcription factor IIIB 50 kDa subunit
Sequence:
MAAAADERSPEDGEDEEEEEQLVLVELSGIIDSDFLSKCENKCKVLGIDTERPILQVDSCVFAGEYEDTLGTCVIFEENVEHADTEGNNKTVLKYKCHTMKKLSMTRTLLTEKKEGEENIGGVEWLQIKDNDFSYRPNMICNFLHENEDEEVVASAPDKSLELEEEEIQMNDSSNLSCEQEKPMHLEIEDSGPLIDIPSETEGSVFMETQMLP
Protein: Cysteine peptidase (EC 3.4.22.-) (Q585E2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Inhibitor of cysteine peptidase
Sequence:
MPRTEMVRFVRLPVVLLAMAACLASVALGSLHVEESLEMRFAAFKKKYGKVYKDAKEEAFRFRAFEENMEQAKIQAAANPYATFGVTPFSDMTREEFRARYRNGASYFAAAQKRLRKTVNVTTGRAPAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTIDSGCNGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLPQDEDAIAAYLAENGPLAIAVDATSFMDYNGGILTSCTSEQLDHGVLLVGYNDNSNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVVGGPTPPPPPPPPSATFTQDFCEGKGCTKGCSHATFPTGECVQTTGVGSVIATCGASNLTQIIYPLSRSCSGPSVPITVPLDKCIPILIGSVEYHCSTNPPTKAARLVPHQ
Protein: DNA-directed RNA polymerase subunit (EC 2.7.7.6) (A0A0R4I9V4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- DNA-directed RNA polymerase I subunit RPA49
- DNA-directed RNA polymerase subunit
- DNA-directed RNA polymerases I and III subunit RPAC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase I subunit RPA2
- DNA-directed RNA polymerase I subunit RPA43
- RNA polymerase I and III subunit C.
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- RNA polymerase I-specific transcription initiation factor RRN3
Sequence:
MQFSKETPWRRLEGMSFGLFSADETRKLSVKTITNPQLLDNVGNAAANGLYDLALGPADNKEICSTCMQDFSSCPGHFGHIELPLPVYNPLFFDKLYLLIRGSCLSCHILKCPRAAIHLLLCQLKLLDVGAMKEVFEIENVLNQFLESNPSPPGEEIQETLNDFVKPILETRKDKQHTDPVKHICEKKSSLITSFWRIHMGPKKCQNCKANRMTVRKEHNSKLIVTQTLHKKASEQDDDSQLTKRIFLTPSVAREHIIKLWETEGFFLKHLFSGFDMDNSDNGFNPEVFFLELLVVPPCRYRPINRLGDQMFTNGQTVNMQAVLKDGLIIQKLLTLIADEKTKAIEGTQTELEQSSEAPKVTEIDQSFLTSIQGVTLTDKLYSTWIHLQSLVNIVFDSDMDKLITEKFPGVRQLLEKKEGLFRKHMMGKRVDYAARSVICPDMYIGTNEIGIPMVFATKLTYPQPVTPWNVKEMRQAVLNGPNIHPGATMVVNEDGSRTILSSTNQTQREAVAKQLLTPSTGQHRIPMKIVNRHIKNGDVLLLNRQPTLHRPSIQAHCARILPGEKVLRLHYANCKAYNADFDGDEMNAHFPQSELSRAEAYTLVSTDQQYLVPKDGKPLAGLIQDHMVSGTSMTIRGCFFTRDQYTALVYRGLTDKIGRVKLLPPTLIKPVLLWTGKQVVSTLLLNVIPENSIPLNLTGKAKIPGKAWVKESPRPVPGYVPESMCESQVVIRQGELLMGVLDKAHYGSSAYGLVHCCYELYGGETSGKLLSCLARLFTAYLQLYRGFTLGVEDILVKDGANKQRKKIIKKSVTCGSKALQAAFNLPASAEDTEARERWQDAHLNIDQRDFNMVDLKFKEEVNQVNNNINKVCMPLGLHRSFPENNLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMPSGKSLPCFQPYEPQPRSGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCVIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPRQFPFIKDNYEVIRKSKCLDEVLAKMDPVAALNHFKAIKKWKAKHEHASPRDGAFLLFSQKKMSKLKAQVEGHELVNGREEATLQLIERWRALDESGRMRYSKKTSHCPEPCLGLYRPDISFGSVSETFDSIVESYLNQFNIKQEFSASSETTDADRLRNLLQLKWQRALCDPGEAVGLVAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILLVASSNIKTPMMSIPVVMNKKALKQVKTLRKKITRVCLSEVLHKVNVIESFRMPKKETLKSRVFKITFHFLPPERYQQDKLLNPDEILHYMEQTFFRMLLEAIKKLTAKLAAISLVETRRATVNDNDRDTSDGGADREDNGGEDAENERIVDDEANEGDADATDSKRKEKQEEEVDYESEEGEEGSDQEQEEVAEEQEASQEVSEEGSTESQQRVNSEQPKGSSQGSVRINSVLQLSAAIEDYKYDTKKGLWCELTLVMPITKVHFDLTSVVVKQAQNAVIMETKGITRCLLNEVTRKDGSKEIMLNTEGINIHEMFKYADILDLKRLYSNEVHAMASTYGIEVALRVIEKEIKDVFAVYGIEVDPRHLSLVADYMCFEGVYKPLNRFGIQSNSSPLQQMTFETSFKFLKQATMLGSYDKLSSPSACLVVGKVVKGGTGIFDLKQPLQ
Protein: Ankyrin 2 (A0A5F9ZGX8)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MTTMLQKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGRASPCLERDNSSFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIRRYVSSEGTEKEEIMVQGMPQEPVNIEEGDGYSKVIKRVVLKSDTEQSEDNNE
Protein: UDP-glycosyltransferase 73C7 (EC 2.4.1.-) (Q9SCP5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Endoglucanase 7
- U-box domain-containing protein 51
- U-box domain-containing protein 34
- U-box domain-containing protein 52
- Galactinol synthase 5
- Putative U-box domain-containing protein 53
- Galactinol synthase 10
- Galactinol synthase 6
- Galactinol synthase 7
- U-box domain-containing protein 33
Sequence:
MCSHDPLHFVVIPFMAQGHMIPLVDISRLLSQRQGVTVCIITTTQNVAKIKTSLSFSSLFATINIVEVKFLSQQTGLPEGCESLDMLASMGDMVKFFDAANSLEEQVEKAMEEMVQPRPSCIIGDMSLPFTSRLAKKFKIPKLIFHGFSCFSLMSIQVVRESGILKMIESNDEYFDLPGLPDKVEFTKPQVSVLQPVEGNMKESTAKIIEADNDSYGVIVNTFEELEVDYAREYRKARAGKVWCVGPVSLCNRLGLDKAKRGDKASIGQDQCLQWLDSQETGSVLYVCLGSLCNLPLAQLKELGLGLEASNKPFIWVIREWGKYGDLANWMQQSGFEERIKDRGLVIKGWAPQVFILSHASIGGFLTHCGWNSTLEGITAGVPLLTWPLFAEQFLNEKLVVQILKAGLKIGVEKLMKYGKEEEIGAMVSRECVRKAVDELMGDSEEAEERRRKVTELSDLANKALEKGGSSDSNITLLIQDIMEQSQNQF
Protein: Uncharacterized protein DDB_G0292160 (Q1ZXA8)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Roadblock/LAMTOR2 domain-containing protein
- Ragulator complex protein LAMTOR3 homolog
- Ragulator complex protein LAMTOR5 homolog
- Ragulator complex protein LAMTOR4 homolog
Sequence:
MGCVVSKSDDIKNENESRQRNQASSSQQPSSSQTPSKQIGIAAKDSEEQPQEVSYSQMRELDNDFFKDIIDRTAQKFIDVSMVGPDGKDSFLDREKDYSAQIKDSKLLKPTSLTSLPRLSQQCQMSNLQNLLSQPTTFDNELMSKYTSSISENLNGIHIKECGELVVFFGNSLK
Protein: Alpha-(1->6)-mannopyranosyltransferase A (MptA) (EC 2.4.1.-) (Polyprenyl-1-monophosphorylmannose dependent alpha-(1->6)-mannopyranosyltransferase) (PPM-dependent alpha-(1->6)-mannopyranosyltransferase) (O53508)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the latter stages of the biosynthesis of the alpha-(1->6) mannan core of lipomannan (LM). Catalyzes the addition of alpha-(1->6)-mannose residue.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- 
- Alpha-
- Polyprenol-phosphate-mannose-dependent alpha-
- Terminal beta-
- Probable mannosyltransferase. Probable conserved transmembrane protein
- Probable unidentified antibiotic-transport integral membrane ABC transporter
- Probable unidentified antibiotic-transport integral membrane ABC transporter
- GDP-mannose-dependent alpha-
- Alpha-
- Probable arabinosyltransferase C
Sequence:
MTTPSHAPAVDLATAKDAVVQHLSRLFEFTTGPQGGPARLGFAGAVLITAGGLGAGSVRQHDPLLESIHMSWLRFGHGLVLSSILLWTGVGVMLLAWLGLGRRVLAGEATEFTMRATTVIWLAPLLLSVPVFSRDTYSYLAQGALLRDGLDPYAVGPVGNPNALLDDVSPIWTITTAPYGPAFILVAKFVTVIVGNNVVAGTMLLRLCMLPGLALLVWATPRLASHLGTHGPTALWICVLNPLVLIHLMGGVHNEMLMVGLMTAGIALTVQGRNVAGIILITVAIAVKATAGIALPFLVWVWLRHLRERRGYRPVQAFLAAAAISLLIFVAVFAVLSAVAGVGLGWLTALAGSVKIINWLTVPTGAANVIHALGRGLFTVDFYTLLRITRLIGIVIIAVSLPLLWWRFRRDDRAALTGVAWSMLIVVLFVPAALPWYYSWPLAVAAPLAQARRAIAAIAGLSTWVMVIFKPDGSHGMYSWLHFWIATACALTAWYVLYRSPDRRGVQAATPVVNTP
Protein: Ammonium transporter 1 member 1 (LeAMT1;1) (P58905)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Ammonium transporter that may be involved in ammonium uptake from the soil.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- PII protein
- PII-like protein
Sequence:
MACSVDTLAPFLGPNTTNAVAAASYICNQFSGVSDRFVDTGYAIDSTYLLFSAYLVFSMQLGFAMLLAGSVRNTMNIMLTNVLDAAAGGLFYYLFGFAFALGGPSNGFIGRHFFGLKEIPSNSFDYMNFLYQWAFAIAAAGITSGSIAERTQFVAYLIYSSFLTGFVYPVVSHWFWTPDGWASPTNSNLLFGSGVIDFAGSGVVHMVGGIAGFYGALIEGPRIGRYDHTGRSVALRGHSASLVVLGTFLLWFGWYGFNPGSFNKILVTYGASGGYYGQWSAVGRTAVTTTLAGCTAALTTLFGKRILSGHWNVTDVCNGLLGGFAAITAGCSVVEPWAAIICGFVAALVLIGFNMLAEKFKYDDPLEAAQLHGGCGAWGIIFTGLFAKGEFVDQVYPGKPGRPHGLFMGGGGKLLGAHIIQILVIIGWVSATMGPLFYILHKFKLLRISSEDEMAGMDLTRHGGFAYYHEEDPKLGMQMRRIEPTTST
Protein: Beta-1,3-glucan-binding protein (BGBP) (Beta-1,3-glucan recognition protein) (BetaGRP) (Gram-negative bacteria-binding protein 3) (GNBP3) (Q9NL89)
Organism: Bombyx mori (Silk moth)
Function: Involved in the recognition of invading microorganisms activating the phenoloxidase cascade. Binds specifically to beta-1,3-glucan. Binds to both curdlan, a linear water-insoluble beta-1,3-glucan polysaccharide, and laminarin, a water-soluble beta-1,3-glucan polysaccharide containing beta-1,6 branches.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q76DI2}.
Interaction partners:
- Peptidase S1 domain-containing protein
- Uncharacterized protein.
Sequence:
MYKTCVWVLLFKIVLCYEAPPATLEAIHPKGLRVSVPDEGFSLFAFHGKLNEEMEGLEAGHWSRDITKPKNGRWIFRDRNAALKIGDKIYFWTFVIKDGLGYRQDNGEWTVEGFVDEAGNPVNTEGSEITPGVEFTSTSLNPESPQSIPNQPPDNLPAKPPSEGYPCELSLSTVSVPGFVCKGQLLFEDQFNIPIHRGKIWVPEVKFPGEPDFPFNVYLSDNAEVNDGKLIIKPATLESKYGEDFVRQSLDLSERCTGTVGTAQCLREASGPLILPPIITAKISTRHQFAFKYGRVEIRAKMPKGDWLYPEILLEPRDNIYGVRNYASGILKIASVKGNAEFSKKLYAGPIMTGSDPYRSFYLKENIGYESWNNDFHNYTLEWRPDGITLLVDGESYGEIKPGEGFYNVANSYKVEAAPQWLKGTIMAPFDELFYVSIGLNVAGIREFSEDISNKPWKNSATKAMLKFWDARSQWFPTWDEDSALQVDYVKVFAI
Protein: Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1) (EC 2.4.3.1) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1) (ST6Gal I) (ST6GalI) (Sialyltransferase 1) (P13721)
Organism: Rattus norvegicus (Rat)
Function: Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:3121604}; Single-pass type II membrane protein {ECO:0000305}. Secreted {ECO:0000269|PubMed:11278697, ECO:0000269|PubMed:3121604}. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. {ECO:0000269|PubMed:11278697, ECO:0000269|PubMed:3121604}.
Interaction partners:
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase 3
- Beta-1,4-galactosyltransferase
- CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
- Beta-galactoside alpha-2,6-sialyltransferase 2
Sequence:
MIHTNLKKKFSLFILVFLLFAVICVWKKGSDYEALTLQAKEFQMPKSQEKVAMGSASQVVFSNSKQDPKEDIPILSYHRVTAKVKPQPSFQVWDKDSTYSKLNPRLLKIWRNYLNMNKYKVSYKGPGPGVKFSVEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKVGPWQRCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGSKTTIRLMNSQLVTTEKRFLKDSLYTEGILIVWDPSVYHADIPKWYQKPDYNFFETYKSYRRLNPSQPFYILKPQMPWELWDIIQEISADLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHPLLFEKNMVKHLNEGTDEDIYLFGKATLSGFRNIRC
Protein: Voltage-gated inwardly rectifying potassium channel KCNH6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Potassium voltage-gated channel subfamily H member 6) (Voltage-gated potassium channel subunit Kv11.2) (O54853)
Organism: Rattus norvegicus (Rat)
Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current. Channel properties may be modulated by cAMP and subunit assembly.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q12809}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q12809}.
Interaction partners:
- Sigma non-opioid intracellular receptor 1
- Voltage-gated inwardly rectifying potassium channel KCNH2
Sequence:
MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVMQRPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKSSSRSLTQRLLSHSFLGSEGSHSRPSGQGPGPGRGKYRTVSQIPQFTLNFVEFNLEKHRSGSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADVLPEYKLQAPRIHRGTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESQRGTCGYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAAIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNVERPYLEPKIGWLDSLGAQLGKQYNGSDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHCPAFRGASKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDDVVVAILGKNDIFGEPASLHARPGKSSADVRALTYCDLHKIHRADLLEVLDMYPAFADTFWNKLEVTFNLRDADGGLQSTPRQAPGHQDPQGFFLNDSQSGAAPSLSISDTSALWPELLQQMPPSPPNPRQDLDCWHRELGFKLEQLQAQMNRLESRVSSDLSRILQLLQHPQGRPSYILGASASSDLASFPETSVTRSSESTLLVGHVPSAQTLSYGDLDDHIQTPRNFSPRTPHVAMAMDKTLVPSSEQEQPGGLLSPLASPLRPLEVPGLGGSRFPSLPEHLSSVPKQLEFQRHGSDPGFTRS
Protein: LD34461p (Translocase of outer membrane 20, isoform A) (Translocase of outer membrane 20, isoform B) (Q95RF6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004572}.
Interaction partners:
- FI03495p
- Mitochondrial import receptor subunit TOM40 homolog 1
- Mitochondrial import receptor subunit TOM7 homolog
- Serine/threonine-protein kinase Pink1, mitochondrial
- Mitochondrial import receptor subunit TOM22 homolog
- Voltage-dependent anion-selective channel
- Mitochondrial import receptor subunit TOM40 homolog 2
- Cytochrome c-2
- Mitochondrial fission 1 protein
- Cytochrome c-1
Sequence:
MIEMNKTAIGIAAGVAGTLFIGYCIYFDKKRRSDPEYKKKVRERRRRNKKTGTAKSGVPNLNDHEAIERYFLQEIQLGETLIARGDFESGVEHLANAIVVCGQPARLLQVLQSSLPAQVFAMLIVKMQEFGNRAAEGNDGPIVLGQSSEQQLDGAKIIECSSGNASIDDLE
Protein: Metal-binding activator 1 (Q5AFK0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Copper ion-sensing transcription factor which activates transcription of the CTR1 copper transporter under low-copper conditions. Promotes filamentous and invasive growth.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MILIDDIKYACMECVRGHRSSSCKHHERPLLQVRSKGRPGVYANGNPNHRVAIFAEEIAKSDKPSTNGTKRCKSEPIIVLKASSKQVIDCSSGVIIGPYDETKTKPSTVEKRTPSPPIISDESFINTSACCTPKISKGKSCGCCNNKRKAVNKSKILQNYIKNKLNQKINNNETLVFMNKSHTTNNEQKEDHQLYGMVPVPSCSIPGTCCCDDACSCQGCVVHGNSKYQIPLPTSKQQVTDTTNPFENEEKFIFNSMPQTDKSDLFFNTISTSSNVPPADSSSECSCPPNACDCTNCETHGILNGFRLDDYFKDQSKLMNVLDFNFSELLGTIPEQPIPTEFMQPPSENTLLTSLSSENSFIPNQTKELSTQPPILPLDAQNVCNELDQLEPLVPSLQPCDKKATKWVNNRDTLEDVSDNRVKSCCSKKTK
Protein: Glucosamine 6-phosphate N-acetyltransferase (EC 2.3.1.4) (Phosphoglucosamine acetylase) (Phosphoglucosamine transacetylase) (O13738)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Probable glutamine--fructose-6-phosphate aminotransferase
- Phosphoacetylglucosamine mutase 1
- Phosphoacetylglucosamine mutase 2
- Hexokinase-1
- Hexokinase-2
- Probable UDP-N-acetylglucosamine pyrophosphorylase
- Uncharacterized protein C1734.10c
Sequence:
MKKDFHSTYYIIVVEDLESHHVIGTATLFLERKFLRGKGICGHIEEVIVHPDHQRKAIGKLMVLTLIKLAFSLNSYKVILDCSDSNVGFYEKCGLSRAGIEMKKYASHSII
Protein: Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1) (O95490)
Organism: Homo sapiens (Human)
Function: Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Teneurin-2
- Teneurin-4
- Teneurin-1
- Teneurin-3
- Netrin receptor UNC5D
- Netrin receptor UNC5A
- Netrin receptor UNC5C
- Guanine nucleotide-binding protein G
- UNC5C-like protein
- SUZ RNA-binding domain-containing
Sequence:
MVSSGCRMRSLWFIIVISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPGTLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNSIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTIISTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVSTTKIPPITNIFPLPERFCEALDSKGIKWPQTQRGMMVERPCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLHKGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKTHNLELTLPVKPVIGGSSSEDDAIVADASSLMHSDNPGLELHHKELEAPLIPQRTHSLLYQPQKKVKSEGTDSYVSQLTAEAEDHLQSPNRDSLYTSMPNLRDSPYPESSPDMEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL