Protein: E3 ubiquitin-protein ligase ptr1 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase ptr1) (Poly(A)+ RNA transport protein 1) (O13834)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable ubiquitin ligase protein involved in mRNA export. E3 ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. Probably participates in mRNA export from the nucleus by regulating the transport of hnRNP proteins such as rae1.
Subcellular location: Nucleus.
Interaction partners:
- Polyubiquitin
- E3 ubiquitin-protein ligase ubr11
- E3 ubiquitin-protein ligase ubr1
- Elongation factor 3
- BAG family molecular chaperone regulator 1B
- AN1-type zinc finger protein C1271.05c
- Uncharacterized RNA-binding protein C106.12c
- Ubiquitin-activating enzyme E1 1
Sequence:
MRITKSPPKNQYSQPPPRVAEFIRQAQNEEVTSDLGLVSLCSEFRKNDWPYPRGDLYSWVPVLNRFDAILERIVEHYSLKDKVQTKPFDSDTLSILLEILSFSAHLLSHCANRSIYNSTVYLEYLLNSSVLEVIDSTLALLLHIVQKATISKRGKQLFSLSQDRLFRFLMFLPQDAMKTGFSQNYETLLFSNEIPQEWCSLELSYYKSSPSKDFSSASQPNSEGFSILKLPYNKVLGKPIEELLVKTLHDNQIPEQYSFDLLVSLMLRQNLYDINRRRLMIRIGLLALSNLVYAHSQAVQTRFLIADPEITTHLANLVSPDVDLPQNFKAVCFECFKAFFFKKSMIPSVLASLNVSVSYGLMMNLVRDFSKNLENPNFYYEREYVDSFYDFLQFMTSSPLGGNMACSAGLTSLLGYHLSVKTPQATYVVARSIVMLDHLIDGYSMAFPDFSESKGLDMLVDRVQYELEAGLQDIKSGKGNPEIVLNMDYAISYDRYFLLKNLLKFVLHLIQSGGSVVELRNLIDSSLISSLAFLLEHHEVYGSNLFASTTNIMSTFIHNEPTCYGIIHEKKLSHAFLDAVNRKILNSSDAITSIPLAFGAICLNSQGFDLFLEKNPIPQLFSIFTSLNHCKSLISSDNAAILGTYIDELMRHQPSLKDPIVKMIFKACDQVSALLDNFNPFQYINAKEYPYLLYLETFSSFLENIITNEGHARYLISKGIVSHVLNLIQHPVLAFGFIDSSAFNSFFVLLHHAVDFDAPEVFRPLLDCIITRCEEGITEFTIVSLKQATISLIKDSNMGHEDANNFLHFSIVGNLLTIFAELFSSHAALKKAGNLPLVQLFISPSRYAGIFDILCNIKSIATSLDIHICLGVSDDFVLCSDSLTTIVTDKDEKEKFETKKKELTQDSSFCKFQNIRSNFSQIAYGVSKFFTSLTRALGNTSVQDFNEYKMIHKLGSNIALVVDELINLSSKQITSHPQSLSIASLEASLIFVLGASSIIREDDSKVTLVLLISRLLGGCRTMDVLISLNETVSGFFRLSDRDPLSKSNRVLLALSSTLLNLILVFTSADFMSETSKTLNMALKSEFDMTDFNNSGSKLMHVLHARIFISVLHLWRSADDLHLPYITRALLTNVLSNCYQFEDGIKNVVDSINNLRTSIANGDIKEPLDVVTDDNTNSNFSLEETNASVTDMPESEKHENGIFQAYLLKEMPNDIVSQFEMLKSKQIELTVQMASYEGDLNQNLCDFLYTRDDVQMNADVQFSVTSGLIVEIKKLAQSTDCKAKNQLGPAVGLLSLFISHDFTQNKAKNCVLSELNFFLELLHSLNNGLPSDSHKTSIVCILYLLEVLLADSKKPDEFEFNSEDCSLKLTDGAITVDLASQKHIMSSVITLLSLNSANLGVVVSAFRVVVLLTSASEMIHTFVKLSGLPSLFKAMRACSGFCNESLHIPFISILRRLLEFDEVVELMMFDDLVNIFKLQGRARKTELHGFIRANAEMVLRSPECFIKILKDCCVLGHFTPESEHYYLELKESLPGVLQNGQTDLDPSKEQMSSVIVSFLLDELMDLTETRQFSDRSPNSEFTPENDSLYMYNVFLLQCLTELLSGYNACKRCFLNFQPRRKAPFFNLSRKYNSYLVGFFLEKLLPFGCIRLSENNEVRKAFSVSNWAISILVFLCAYSNEQQTQAVDEIRREVLTSVLKFYKSSSSFSENLEAYYCKLLVLAELCYRLCDAQTVSQKAPNHLLRRSQDQNVKTMIDLGYIPTLTNAISEIDMNYPVSRKVVRHILKPLQLLTKEAIFLSQTNPEALSGAAQDSMGDQSLSSSSEESSDSDREEPPDLYRNSVLGIFQGDIVNENDENYEDSEDDGVYEEMEFEDDQSGSADSVVSEDDADDVMYSDNDDMNIEFMVDEQDASSQNDDSSFDEASSHGDVISIDEEDLDNQGEEFEWEDEDNASSGYEDELDYNEDEVGENDSTTFEAMENAFTETSDNDDHLEEADHVSPVEIDFLENDENSSSEQDDEFQWEWNTETPSGADILSRHGALLRDLFPLPGLSRRVMIINSNDPSRSRPFLNNNASEGLLKHPLLLRNNLIHTPKATELWENLAEIDNHTASGAAFQRLLYYLALEIPNEDSSVLGWTSLKVSKHTDPLRATSDFIPLFSMQRWNSITSMFFAHASGSIALRITGSVLFALVPPALEKYNLENQKKEILENESKEEETRQPEVNIQPEEPINTSDMEGVTTEANEIGSYQEPSLINIRGREVDVSSLGIDPTFLLALPEEMREEVVFQHIQERHMESISDSSRRIDPSFLEVLPSDLRDELLFQEAVQMRLFDHATRNNNSVDHEVEMEEIDQGGTVSEHREKSVKPVKKIPVPNLLDRQGLYSLIRLIFISQHNGKNPYYDLIVNISENKQHRADIVGLLLYILQEASINDRASEKCYRDLTVKSLNNSQQKEVKKSTGLLESLCKVPVVNGISAPALILQQGIDLLSHLATWADHFASFFLSMHDFSGIASKKSAGRKNRESNVYKIAPINVLLGLLAREELFGNTLVMNTFSELLSTLTKPLLSFYKSEKLQKDSATTGYTNDQDSRGSTVPKQDPGTTASRKDKKILSPPNILDENLRLAASLITTDSCSSRTFQNALSVMFHLSSIPKAKILIGKELLRHGQEYGNSITNDLSRLCADVKSGKNESELQVALAPFCPASSNQAKLLRCLKALDYIFERRPKGQEQSPGNIIQLLEFYDNLKFSSLWEVLSECLSALRDHTSITHVSTVLLPLIESLMVICRLVFIELPEDVGKHISPILERFKTLFISFTEEHRKIINMMVFTTPSLMSGSFSLLVKNPKVLEFENKRNYFNRQLHEEAAKEQYPPLNITVRRDHVFLDSYRALHFKDADEVKFSKLNIHFRDEEGVDAGGVTREWLQVLARQMFNPDYALFLPVTGDATTFHPNRDSSVNPDHLSFFKFTGRIIGKALYDGRLLDCHFSRAVYKHMLHRSVSVKDIESLDPDYYKSLVWMLNNDITDIITEEFAVEKDVFGEKTVVDLIPNGRNIPVTELNKQNYVNRMVDYKLRESVKDQLKSLLDGFSDIIPSHLIQIFNEQELELLISGLPEIDIDDWKNNTEYHGYNVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSYGSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEGSEGFGFA