wanglab/gogpt-training-data huggingface dataset:
Protein: Anion exchange protein (M9PB59)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Membrane {ECO:0000256|RuleBase:RU362035}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362035}.
Interaction partners:
Sequence:
MNSSSGDDEAPKDPRTGGEDFTQQFTENDFEGHRAHTVYVGVHVPGGRRHSQRRRKHHHSGPGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGMLVKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIRSLADMRNHSSSKKKKSNSKHSRPAQNLSSITEDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEEARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSNASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAGANYNADKSGPTTIHIPLSGNKTGTKGPTVNIPQEAVNRTAVWQQINKDGNGISEQLIIPVTLKVRQINGNQTQNLIRRSNCGVDILHQQKHPFESMI
Protein: Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B) (P27987)
Organism: Homo sapiens (Human)
Function: Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12747803}. Cytoplasm {ECO:0000269|PubMed:12747803}. Endoplasmic reticulum {ECO:0000269|PubMed:12747803}.
Interaction partners:
- Inositol polyphosphate multikinase
- Inositol polyphosphate-5-phosphatase A
- Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
- Inositol-trisphosphate 3-kinase A
- Multiple inositol polyphosphate phosphatase 1
- Inositol-tetrakisphosphate 1-kinase
- Inositol polyphosphate 5-phosphatase K
- Inositol-trisphosphate 3-kinase C
- Calmodulin-1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Sequence:
MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA
Protein: Pyridoxal kinase PdxY (PL kinase) (EC 2.7.1.35) (Pyridoxal kinase 2) (PL kinase 2) (P77150)
Organism: Escherichia coli (strain K12)
Function: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP in vivo, but shows very low activity compared to PdxK. Displays a low level of pyridoxine kinase activity when overexpressed, which is however not physiologically relevant.
Interaction partners:
- Pyridoxine/pyridoxamine 5'-phosphate oxidase
- Pyridoxine 4-dehydrogenase
- Pyridoxine 5'-phosphate synthase
- Pyridoxine/pyridoxal/pyridoxamine kinase
- Pyridoxal phosphate homeostasis protein
Sequence:
MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIAKPEHYFSATKL
Protein: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (F4J432)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MVTPMSNRKHMVMSLIEKAARFFFTRFLTHFISTGCVTIFEGGNMVTFEGKDSRCHLKSELEIHSPQFYWKVMTQVDLGLADAYINGDFSFVNKETGLLNLIMILIASKELNSNLAEKRGRWTPIFLTTGLSSAKHFLKHLYRQNNLTQARRNISRHYDLSNELFTIFLDDTMSYSSGVFKSDDEELKIAQMRKIYLLIEKTAYLSCSIENVENIGIHYYQTLRLWRKNFFERQKQITDLGFDDRFVRTCEYYFDYCAAGFKTRTVGDYQIVFSRPGNVIALGDDSFYSSPLTQKKQLQMNHFDS
Protein: Erg protein (Transcriptional regulator ERG) (V-ets erythroblastosis virus E26 oncogene like (Avian)) (Q5PR65)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU004019}.
Interaction partners:
Sequence:
MTASAAAELPHSKLLLSAVSVKLEASAGAHRSHCRSPPDDCPGVKGKISPAGNAPVMYSNYMEEKHTPPSSERRVIVPADPGQWSAGHVRQWLDWAVQEYGLPPLDVSLFQGVDGKQLCRMSREELQRLTSSYSADVLLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGANFIFPNTPVYPPDASRGASRAGVGYDAVRRSGWTPALPAAKVSQSSAAIMSKTEEQRAQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSCNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPDSSIYKYPAVAADLPYVSSYHPQKMSFMAPHPQAMSVSSSGFFSGPAPYWNTPAAGIYGGPRHPPAHMPSHLGSYY
Protein: Nhs protein (B7ZWM3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MPFAKRIVEPQWLCRQRRPAPGPDEDTSGGSVEPPPPLQPPGRREEAEAPEPEEPPRVPPAPLPLPPLPPSLPAPAEQDQQPPSEAREAGEESVAGVSEAASAPGETSEASAEAVLLMLDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGSVQRVLSTLDPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLQATRPPCVEELHRHARQSLQALRREHRSRSDRREQRAAAPLPIAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMAPWSRKSHSPEDEDTDAMLGQRPKNPIHNVPSTLDKQTNWNKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTMFTPVVSSRTRSRSLPREGNRGGDAEPKVGAKPSAFEEGERFVGDHERTPNDCSEAPSSPSTQEHQPALGLACSQHLHSPQQKLSERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTASVLLSSHMDQKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPNANEDASVFVTEQYNDHLDKVRGHRTNSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMGTYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGNKTYVCHYAGLGPENGQGVGVPPALPDCAWQEYLDHRRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLPHSSREMKLPLDFSNTPSRVENANLPAKLDSSWINQSEHAIKEPQLDTPDISPFKDEGAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEYKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDFELPIIPPSHLDLSALHVLNKPFHHRHPLHVFTHKQNTVGDMPRSNPAPSLAITPTVLKSVNLRSISKSEEVRQKEGNNTDLPYLEENAATAASVASLSPSKARPHTAKKSISRQYSAEDTLLPFLDSSVAEMGPEKHLEKNPNFDGKSHGDPETATSASSNLPDSNVMKEQIQMESELISENILSKNCGFSTGFQRVSASRPSDLGSKMIQYGASPDGTVQQGQKAPSGVREEGGKPESVDGITLQANSSTRVTDISSQYKHQRVISRHHDKVPVTIRHESEMSTVNSFPEKCSEQENIASGISPQSASDNSRAEETQGSMDETSLKESSPSDDSITSPLSEDSQAGAEGVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRVPLGSSSSSANSVTSPSSNVTAGTSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPVLPKPPGEFTAESPQSPDDTHQGTPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRVPPVASSSRYSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST
Protein: Interleukin 18 binding protein (A0A8I6AG06)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTMRHCGCAADPSPWWVLLLYVHVVILARATSAPLTTATVLTRSSKDPCSSWSPAVPTKQYPTLDVIWPEKEVPLNGTLTLSCTACSRFPNFSILYWLGNGSFIEHLPGRLREGHTSREQRNASTWLHRALVLEELSPSLLSTNFSCLFVDPGQVAQYHVILAQLWVRNLKEGIQGWEELHYLGKKGLAFPMQPVSGDC
Protein: HAT C-terminal dimerisation domain-containing protein (Q4PIU4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MLYKCCKCLALLNKNSMVIVPKDPENLKNWMEKYDFQIKTIMAGSVHFLCKTHLSEDKSVERIPSSSVESATEQYMLEIKEEEPYSQAGSSSESWPEVKEEVIEPVEEIDYDHMPFEIEQNSYETFDESKSYHNSYESDHHQPTTSTSATRAIRRPTTKSLEFTNLPTYLQELSDGEILSFCVKTSSNLSGATSLECGMCEEQYFNSTDTRPIRHHLISRHEATMKKYKNHFPITAAPKIYAPIQQVTIDRADQALTKFFIKSGIPLRAVQDRNLNMLAFNMNSEYSLPTVETMHSFLEKIADAKANAKLNFDDSPVTITFDTTTFNNRHYLAFTVHYYHIRSRMRRCIFLREYDMTGPIVPSVMTAIQKTIEESGSRLKITTVVAGKAEFEDALEDMHSFKQVMICFSQNINKFAETLIEHPVFAGPLQKLRDFITKFPTHRNSWGKFKSYIVKKRTYGEYPEVDNGHWITTLDFITKCLHMHRLFSEFVSTSAQLQYIDVEDNVNIVYLHSLLNLCKSALKEMVDVKATIADVIPAIADISFSLIVTTSKQTVVDAVSTIFNQLLLPFVEQSDIHRFALFLHPLRHGSDLLASADWMKIKTDLSSHLSLREAAEATLAHPSSFDNTITADKEVNAFSQYVCRVTGVETGIMDWWARHAGRFPRLYKYARELFIIPAFSIDAAYYLGEYGILTHSINESDISKRKMLLRAASELVEYRSKGSLMCKPICVKRRKDANSPEDAWYHAIDVRALQIVDVPSDEPPKRMIPQRTPFVYQNPNPLPPHRILQSFPTIRTNREAPHGRSLKDEIAKIAANRQKIQRVYTVASSSPYARPVVVKTESKEGIVEQLTPSAPPPKRYYAVRPAAGNGTSVIRGKDESPST
Protein: Pre-mRNA-splicing factor cwf18 (Complexed with cdc5 protein 18) (Q9UU80)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Pre-mRNA-splicing factor cwf2
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-processing factor 17
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-splicing factor cwf4
- Pre-mRNA-splicing factor dre4
- Pre-mRNA-splicing factor cwf19
- Pre-mRNA-splicing factor cwf14
- U2 small nuclear ribonucleoprotein A'
Sequence:
MSSLDEVAESRKQRLAELRKIKQLENKTRDSQEVQKNVIEHRNYDPEVQAPKMGFVEPPNMIESVEALSKEIEEKTKRKIEEQSSVPVEELDLVTLRPKKPTWDLERDLKERMRSLETQNQNAIAFYIQQLISERAHSTEKA
Protein: Tryptophanyl tRNA synthetase 2 (mitochondrial) (A0A8I6A3I6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MALFSVRKARECWRFIRALHKGPTATAAPQVSEHTQLSWILTCMVRLPRLQHLHQWKAKAARQKHDGTVGLLTYPVLQAADILCYNIHEESEISSPFCQDVKIGP
Protein: EH domain-containing protein 3 (EH-domain-containing 3) (Q5TYP7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Recycling endosome membrane {ECO:0000256|ARBA:ARBA00004159}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004159}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004159}.
Interaction partners:
- Family with sequence similarity 167 member B.
- RING finger protein 145
- Rabenosyn, RAB effector.
Sequence:
MFSWLGTDDRRKKDPEVFQTVSEGLKKLYKTKLLPLEEHYKFHEFHSPALEDADFDNKPMVLLVGQYSTGKTSFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGTMEGLIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELINSLGEIYSRIEREHQISPGDFPNLKKMQEQLQAHDLNKFQPLKMKLLDTVDDMLAHDIAQLMVLVRQEETQRPNQVVKGGAFEGTMNGPFGHGYGEGAGEGIDEVEWVVARDKPMYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSDLPGHLVPPSKRKVPE
Protein: Serine and arginine rich splicing factor 4 (G3V798)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
Interaction partners:
- SRSF protein kinase 1
- Serine/arginine-rich splicing factor 10
- Nuclear RNA export factor 1
- Cell division cycle 5-like protein
- Transformer-2 protein homolog beta
- Tip-associated protein
- Tip-associated protein
- Tip-associated protein
- Nuclear RNA export factor 5
- Nuclear cap-binding protein subunit 1
Sequence:
MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAEDKLQNNDSAGKAKSHSPSRHDSKSRSRSQERRAEEERRSSTSRGHSQEKSLLKSRSRSRSKVGSRSRSRSKSKDKRKGRKRSREESRSRSRSKSERSRKHSSKRDSKVSSSSSKKKKGDTDHSRSPSRSVSKEREHATAEPGQRESRAEGESEGPNPEPRARSRSTSKSKPSLPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS
Protein: Serine peptidase inhibitor, Kazal type 4 (A0A8I6AJC3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MSSDPRSYRAAGTPQGKQAESTIQCWWALAPKSSCSSGRGQKPHQGWSQNPGEASGRRLKEAAAARPGAGALPRAACWRRRRSCRLAVKRRLRPVGAGGSDRDRRELPVSAARLVFSRMPICEHMAEFPNCPRSPNLICGTDGLTYENECHLCVTRMKTKKDIQIMKDGKC
Protein: Nuclear receptor subfamily 4 group A member 1 (H3BPN8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPP
Protein: Phosphatase SCO2771 (EC 3.1.3.-) (Q9L082)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Function: Displays phosphatase activity against p-nitrophenyl phosphate (pNPP) in vitro; however, the physiological substrate is unknown.
Interaction partners:
- Histidinol-phosphatase
- Acetolactate synthase
- Agmatinase
- DNA primase/polymerase bifunctional N-terminal domain-containing protein
- Secreted protein
Sequence:
MPIPGTPSRAELAEHLVRTRIAGDVATPRENNLSHYRKLANGDRGFWLGLELGDRWSDEQDVLAVMAERVGVNDDPEHRYGQDTIDPELTISALERMAGRLRKAADGGQRVLFATGHPGGLLDVHRATAAALRDAGCEIVVIPEGLTTEEGYVQQFADVSVLEHGASLWHTHSGEPMKAILTGLEREGRPLPDLVVADHGWAGYAAQHGVDSVGYADCNDPALFLAESEGTLQVAVPLDDHVVSPRYYDPMTAYLLTEAGLK
Protein: At1g64850/F13O11_15 (Calcium-binding EF hand family protein) (F13O11.15 protein) (Q9XIR0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGQVFNKLRGKEWRHKQVQAICDRVFDRFKMQTGRANLTFEELYIAVLLVYNDINKRLPGPHFDPPSKDLVNSIMTDCDINLDGELDREEFVKFIEQITAETFNVVSQGLIIALIVAPTVAIATKKATEGVPGVGKVVQKLPTSIYASLVTLAVMWVNSDSS
Protein: Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase) (P97328)
Organism: Mus musculus (Mouse)
Function: Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Interaction partners:
- Fructose-bisphosphate aldolase B
- Solute carrier family 2, facilitated glucose transporter member 5
- Triokinase/FMN cyclase)
Sequence:
MEEKQILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAPGHVADFLVADFRQRGVDVSQVTWQSQGDTPCSCCIVNNSNGSRTIILYDTNLPDVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEEHNAKQPLPQKVRVSVEIEKPREELFQLFSYGEVVFVSKDVAKHLGFQPAVEALRGLYSRVKKGATLVCAWAEEGADALGPDGQLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSKGNSMQEALRFGCQVAGKKCGLQGFDGIV
Protein: Calcium-binding protein E63-1 (P48593)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Neither inactivation nor afterpotential protein C
- Inactivation-no-after-potential D protein
- Inositol 1,4,5-trisphosphate receptor
- Transient-receptor-potential-like protein
- Peptidyl-prolyl cis-trans isomerase Fkbp12
- Unc-13, isoform E
- Peripheral plasma membrane protein CASK
- cAMP-dependent protein kinase catalytic subunit 1
- cAMP-dependent protein kinase catalytic subunit 2
- Nuclear factor of activated T-cells 5
Sequence:
MSPMSGLRQQLKMLGTALLGKRATKSVKKKPFTEVEIKDLRTAFDLLDRNRDGRVTANELQFMLKNLGINVSDELIHDLIREASHSGNGLINEAEFLQWVGRIQALRDEQHSHEDSKDSKPVDEADDVTEDLIAAFRVFDRDGNGFITRDELQTAMEMIGEPLNEQQLEQLLVIADLDQDGRINYEEFTRLLL
Protein: Potassium voltage-gated channel subfamily KQT member 5 (KQT-like 5) (Potassium channel subunit alpha KvLQT5) (Voltage-gated potassium channel subunit Kv7.5) (Q9JK45)
Organism: Mus musculus (Mouse)
Function: Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15963599}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Potassium voltage-gated channel subfamily KQT member 3
- Potassium voltage-gated channel subfamily KQT member 2
- Potassium voltage-gated channel subfamily KQT member 1
- Potassium voltage-gated channel subfamily KQT member 4
- ATP-sensitive inward rectifier potassium channel 14
- Inward rectifier potassium channel 2
- ATP-sensitive inward rectifier potassium channel 12
- Inward rectifier potassium channel 4
- Ubiquitin-like protein FUBI
- Sodium channel protein type 10 subunit alpha
Sequence:
MPRHHAGGEEGGAAGLWVRSGAAAAAGAGGGRPGSGMKDVESGRGRVLLNSAAARGDGLLLLGTRAAALGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGIDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTSDKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALTLASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLTRSASANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPMSQNDGSSVVATNNIANQISAAPKPAAPTTLQIPPPLSAIKHLSRPEPLLSNPTGLQESISDVTTCLVASKESVQFAQSNLTKDRSLRKSFDMGGETLLSVRPMVPKDLGKSLSVQNLIRSTEELNLQFSGSESSGSRGSQDFYPKWRESKLFITDEEVGAEETETDTFDGTPPPAGEAAFSSDSLRTGRSRSSQNICKTGDSTDALSLPHVKLN
Protein: Sodium channel protein type 4 subunit alpha (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Q9ER60)
Organism: Mus musculus (Mouse)
Function: Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles, and constant muscle strength in the presence of fluctuating K(+) levels.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11834499}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P35499}.
Interaction partners:
- Sodium channel regulatory subunit beta-1
- Sodium channel regulatory subunit beta-3
- Sodium channel regulatory subunit beta-2
- Sodium channel protein type 5 subunit alpha
- Sodium channel regulatory subunit beta-4
- Sodium channel protein type 3 subunit alpha
- Sodium channel protein type 2 subunit alpha
- Sodium channel protein type 8 subunit alpha
- Sodium channel protein type 9 subunit alpha
- Calmodulin 5
Sequence:
MASSSLPTLVPPGPHCLRPFTPESLAAIEQRAMEEEARLQRNKQMEIEEPERKPRSDLEAGKNLPLIYGDPPPEVIGVPLEDLDPYYSDKKTFIVLNKGKAIFRFSATPALYMLSPFSIVRRVAIKVLIHALFSMFIMITILTNCVFMTMSNPPSWSKDVEYTFTGIYTFESLIKMLARGFCIDDFTFLRDPWNWLDFSVITMAYVTEFVDLGNISALRTFRVLRALKTITVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALVGLQLFMGNLRQKCVRWPPPMNDTNTTWYGNDTWYGNDTWYGNDTWYGNDTWNSQESWVSNSTFDWEAYINDEGNFYFLEGSNDALLCGNSSDAGHCPEGYECMKAGRNPNYGYTSYDTFSWAFLALFRLMTQDYWENLFQLTLRAAGKTYMIFFVVIIFLGSFYLINLILAVVAMAYAEQNEATLAEDQEKEEEFQQMLEKFKKHQEELEKAKAAQALEGGEEADGDPTHSKDCNGSLDTSGEKGPPRPSCSAESAISDAMEELEEAHQKCPPWWYKCAHKVLIWNCCAPWVKFKHIILLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLSVGNLVFTGIFTAEMVLKLIAMDPYEYFQQGWNIFDSFIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKIASDCSLPRWHMHDFFHSFLIVFRILCGEWIETMWDCMEVAGQAMCLTVFLMVMVIGNLVVLNLFLALLLSSFSADSLAASDEDGEMNNLQIAIGRIKWGIAFAKTFLLGLLHGKILSLKDIMLSLGEPGGAGENGESPPEDEKKEPPPEDGNKELKDNHILNHVGLTDGPRSSIEMDHLNFINNPYLTIHVPIASEESDLEMPTEEETDTFSEPEDIKKPLQPLYDGNSSVCSTADYKPPEEDPEEQAEENPEGELPEECFTEACVKRCPCLYVDISQGRGKMWWTLRRACFKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFILEMLLKWVAYGFKVYFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCINTTTSERFDISVVNNKSECESLMYTGQVRWMNVKVNYDNVGLGYLSLLQVATFKGWMDIMYAAVDSREKEEQPDYEVNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGKDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPQNKIQGMVYDFVTKQVFDISIMILICLNMVTMMVETDDQSQLKVDILYNINMVFIIVFTGECVLKMFALRHYYFTIGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSNFAYVKKESGIDDMFNFETFGNSIICLFEITTSAGWDGLLNPILNSGPPDCDPTLENPGTNIKGDCGNPSIGICFFCSYIIISFLIVVNMYIAIILENFNVATEESSEPLCEDDFEMFYETWEKFDPDATQFIDYSRLSDFVDTLQEPLKIAKPNKIKLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALKQTMEEKFMAANPSKVSYEPITTTLKRKQEEVCAIKIQRAYRRHLLQRSVKQASYMYRHSQEGNGDGAPEKEGLLANTMNKMYGSEKEDNGVQSQGEKEKDSTEDAGPTTEVTAPSSSDTALTPPPPSPPPPSSPPQGQTVRPGVKESLV
Protein: Alpha,alpha-trehalose phosphorylase (TPase) (EC 2.4.1.64) (Q8GRC3)
Organism: Geobacillus stearothermophilus (Bacillus stearothermophilus)
Function: Catalyzes the reversible phosphorolytic cleavage of trehalose. Phosphorolysis is specific for trehalose.
Interaction partners:
Sequence:
MSWSISSNQLNIENLLNEESLFFTGNGYIGVRGNFEEKYYDGASSIRGTYINAFHDITDINYGEKLYAFPETQQKLVNVIDAQTVQIYFGEEEERFSLFEGEVIQYERHLHMDKGFSERVIHWRSPGGKEVKLKFKRLTSFIYKELFIQEITIEPVNFFGKTKVVSTVNGDVSNFVDPSDPRVGSGHAKLLTVSDTVIEGDFVSIETKTKRSNLYAACTSTCRLNIDFQREYVKNEKSVETVLTFELTEKAIMTKINIYTDTLRHGDRPLRTGLDLCQKLSCLTFNDLKEQQKHYLDKFWLYADVEISGDQALQEGIRFNLFHLLQSAGRDRFSNIAAKGLSGEGYEGHYFWDTEIYMVPVFLMTNPELAKQLLIYRYSILDKARERAREMGHRKGALFPWRTISGGECSSYFPAGTAQYHISADIAYSYVQYYLVTKDLDFLKSYGAELLIETARLWMDTGHYHEGKFKIDAVTGPDEYTCIVNNNYYTNVMAKHNLRWAAKSVAELEKHAPDTLASLKAKLEITDEEIAEWIKAAEAMYLPYDPTLNINPQDDTFLQKQVWDFDNTPKEHYPLLLHYHPLTLYRYQVCKQADTVLAHFLLEDEQDESVIRDSYHYYEKITTHDSSLSSCVFSIMAAKIGELDKAYEYFIETARLDLDNTHGNTKDGLHMANMGGTWMAIVYGFAGLRIKESGLSLAPVIPKQWQSYRFSIQYLGRHISVSVDTKGTKVNLLNGEELTIKLYGKKHQLTKDEPLEITFNNGRVD
Protein: Noncompact myelin-associated protein (Myelin protein of 11 kDa) (MP11) (Q99JS0)
Organism: Mus musculus (Mouse)
Function: Plays a role in myelin formation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18650334}; Single-pass type I membrane protein {ECO:0000269|PubMed:18650334}. Note=Localized mainly in the Schmidt-Lanterman incisures and paranodes of noncompact peripheral nerve myelin. {ECO:0000250}.
Interaction partners:
Sequence:
MTTATTLGDAVFSLNMTRGEDALYKSSGAIVAAIVVVVIIIVTLVLILLKMYNRRMRTRRELEPKSPKPPVPPALDPSSNGSQQPATVTFDPANVHVETR
Protein: Synaptotagmin-1 (Synaptotagmin I) (P34693)
Organism: Caenorhabditis elegans
Function: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). Involved in necrotic cell death.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Synapse. Note=And vesicle-like structures.
Interaction partners:
- Syntaxin-1A homolog
- Synaptosomal-associated protein
- Ras-related protein Rab-3
- Putative stoned B-like protein
- Synaptobrevin-1
- ATP-grasp domain-containing protein
- MARVEL domain-containing protein
- Phorbol ester/diacylglycerol-binding protein unc-13
- Acetylcholine regulator unc-18
- Endophilin-A homolog
Sequence:
MVKLDFSSQDEENDEDLTKEFVRDEAPMEETTSEAVKQIATTTKETLKDVVVNKVIDVKDVVKEKVMQQTGMPEWAFVFLGFVFILLVLACAFCLIRKLFGKKRHGEKNKKGGLKGFFGKGQDVVDGKNIQGMAQDLEELGDAMEQNEKEQAEEKEEVKLGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIVLMQGGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKVSLMITVMDYDKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTLGPVEEEGDKKDDKK
Protein: Uncharacterized protein (Q54Q52)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSIKKVCCVIGVGKGIGFGVAEKFAKEGFSVALVSRNKEKLEPFVQTIQKKFGDTGSFAVEMDATNAESVEKGFKEIRSKINGRPIDVLIYNASASFKAVSVEKTDVNDFQNAWKASCLGAFLTSQQVLSEMYGQQNGTIIFTGATASLRGGASFGLFASSKFALRGFAQSLARESYPKGVHVSHVIIDGYVDINRDYSSRPKENWIDPDAIASTYFSLYSQDKSAWTHEIDIRPHTEKW