wanglab/gogpt-training-data huggingface dataset:
Protein: Probable prefoldin subunit 5 (Byr1-binding protein Bob1) (O94307)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Required for normal cytoskeletal function and when bound to byr1, is involved in the regulation of sexual differentiation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11683500}. Note=Localizes to the cell tips and septum forming regions.
Interaction partners:
- Probable prefoldin subunit 2
- Probable prefoldin subunit 4
- Probable prefoldin subunit 6
- Probable prefoldin subunit 3
- Probable prefoldin subunit 1
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit alpha
- Probable T-complex protein 1 subunit eta
- Probable T-complex protein 1 subunit beta
- T-complex protein 1 subunit zeta
Sequence:
MAEGNKAVDLTSLSLEQLSEVIKQLDSELEYLSTSYGQLGRAQLKFRECLANVNDAVRAENDGKEVLVPLTSSLYVPGKLNLGNSKLLVDIGTGYYVEKSAGEATEYYKRKCEYLASSIENLNNAIDAKSVQIRAVQNIMQQKATATTAATKSS
Protein: Uncharacterized protein C18B11.06 (Q09713)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Probable U3 small nucleolar RNA-associated protein 18
- Ribosome biogenesis protein enp2 homolog
- U3 small nucleolar RNA-associated protein 6
- Probable U3 small nucleolar RNA-associated protein 11
- Uncharacterized protein C57A7.06
- Periodic tryptophan protein 2 homolog
- Uncharacterized WD repeat-containing protein C2E1P5.05
- Probable U3 small nucleolar RNA-associated protein 7
- KRR1 small subunit processome component homolog
- U3 small nucleolar RNA-associated protein 10
Sequence:
MDVLNKSIQTALEALPKTSSSSSDGVSLVSLKCQLLLSYVQKLAFLMLVKLDDESFLQHQDVVEKLVQLRIEIEKIRPLENRIQYSVDKLLRAAGRKEEIGSIKEPENNGNDKDSQDSLKLHYKPNLSEFADDSDGPASENNVVKEDDKSSISSEDEEEELRSAKDGIYRPPRIRAVTMDSEKRTRHRPNHLVDEFVSSDMSSVPQSMPSVGSNLEKRGRVIHADERELQKMRERIEYEESNYTRLPKLSKKDLKKSKRVKKHDYGGEDWSLLDRKFHDDDFSNRKLDLTSRAKRRANFEDVNDGSLASPVQIGQSYRKRKKNLKRR
Protein: Glutamate/aspartate import permease protein GltK (P0AER5)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glutamate/aspartate import ATP-binding protein GltL
- Glutamate/aspartate import permease protein GltJ
- Glutamate/aspartate import solute-binding protein
- Glutamine-binding periplasmic protein
- Putative ABC transporter arginine-binding protein 2
- ABC transporter arginine-binding protein 1
- Lysine/arginine/ornithine-binding periplasmic protein
- L-cystine-binding protein TcyJ
- Histidine-binding periplasmic protein
- Glutamine transport ATP-binding protein GlnQ
Sequence:
MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVMRLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKRRTA
Protein: Redox-sensitive transcriptional activator SoxR (Q8P6Y4)
Organism: Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Interaction partners:
- Hydrogen peroxide-inducible genes activator protein
- Oxidative stress transcriptional regulator
- VOC domain-containing protein
- Curved DNA binding protein
- Chaperone protein DnaJ
Sequence:
MQRELSVGDVAKRSGVAVSALHFYERKGLIRSLRTAGNQRRYARDVLRRIAVIRVAQRLGVPLQQVLDAFSVLPDQRTPTRAEWARMSARWRGQLDARIAELQALRDQLTDCIGCGCLSLRRCRLSNPGDTLAESGDGAVRLSGTVGG
Protein: Diphosphoinositol polyphosphate phosphohydrolase 2 (DIPP-2) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (EC 3.6.1.61) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4) (Q9NZJ9)
Organism: Homo sapiens (Human)
Function: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. Can also catalyze the hydrolysis of diadenosine 5',5'''-P1,P6-hexaphosphate (Ap6A) but not diadenosine 5',5'''-P1,P5-pentaphosphate (Ap5A) and the major reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Does not play a role in U8 snoRNA decapping activity (By similarity). Binds U8 snoRNA (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12121577}.
Interaction partners:
Sequence:
MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGIFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
Protein: Phytochrome B-2 (I1MGE5)
Organism: Glycine max (Soybean) (Glycine hispida)
Function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
Interaction partners:
- ELF3 protein
- BHLH domain-containing protein
- BHLH domain-containing protein
- Protein EARLY FLOWERING 3
- Protein EARLY FLOWERING 3
- ELF3-like protein 2
- ELF3-like protein 2
- BHLH domain-containing protein
- BHLH transcription factor
- BHLH transcription factor
Sequence:
MASASGAENSSVPPSPLPPPPPPQIHTSRTKLSHHHHNNNNNNNNNIDSTSKAIAQYTEDARLHAVFEQSGESGRSFDYSQSIRVTSESVPEQQITAYLLKIQRGGFIQPFGSMIAVDEPSFRILAYSDNARDMLGITPQSVPSLDDKNDAAFALGTDIRTLFTHSSAVLLEKAFSAREISLMNPIWIHSRTSGKPFYGILHRIDVGIVIDLEPARTEDPALSIAGAVQSQKLAVRAISQLQSLPGGDVKLLCDTVVESVRELTGYDRVMVYRFHEDEHGEVVAETKRPDLEPYIGLHYPATDIPQASRFLFKQNRVRMIVDCHASAVRVVQDEALVQPLCLVGSTLRAPHGCHAQYMANMGSTASLVMAVIINGNDEEGVGGRTSMRLWGLVVCHHTSARCIPFPLRYACEFLMQAFGLQLNMELQLAAQSLEKRVLRTQTLLCDMLLRDSPTGIVTQSPSIMDLVKCDGAALYYQGNYYPLGVTPTEAQIRDIIEWLLAFHRDSTGLSTDSLADAGYPGAASLGDAVCGMAVAYITEKDFLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFKAFLEVVKSRSLPWENAEMDAIHSLQLILRDSFKDAEHSNSKAVLDPRMSELELQGVDELSSVAREMVRLIETATAPIFAVDVDGRINGWNAKVSELTGLPVEEAMGKSLVRDLVFKESEETVDKLLSRALKGEEDKNVEIKMRTFGPEHQNKAVFVVVNACSSKDYTNNVVGVCFVGQDVTGQKIVMDKFINIQGDYKAIVHNPNPLIPPIFASDDNTCCLEWNTAMEKLTGWSRADVIGKMLVGEVFGSCCQLKGSDSITKFMIVLHNALGGHDTDRFPFSFLDRYGKHVQAFLTANKRVNMDGQIIGAFCFLQIVSPELQQALKAQRQQEKNSFARMKELAYICQGVKNPLSGIRFTNSLLEATCLSNEQKQFLETSAACEKQMLKIIHDVDIESIEDGSLELEKGEFLLGNVINAVVSQVMLLLRERNLQLIRDIPEEIKTLAVYGDQLRIQQVLSDFLLNIVRYAPSPDGWVEIHVHPRIKQISDGLTLLHAEFRMVCPGEGLPPELIQNMFNNSGWGTQEGLGLSMSRKILKLMNGEVQYIREAQRCYFYVLLELPVTRRSSKKC
Protein: Sodium/potassium-transporting ATPase subunit alpha (Q6VYM5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU362084}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362084}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGLGKGKDDYKLVATSEDNGNRKSKKEVKKAREKKDMDDLKKEVDLDDHKLTLDELHRKYGTDLARGLTSARAKEILLRDGPNTLTPPPTTPEWVKFCRQLFGGFSMLLWIGAMLCFLAYGIQAASEDEPANDNLYLGVVLSVVVIVTGCFSYYQEAKSSKIMDSFKNLVPQQALVVRDGEKKNINAEEVVVGDLVEVKGGDRIPADLRIVSASGCKVDNSSLTGESEPQTRTPDFSNDNPLETRNIAFFSTNCVEGTARGIVINTGDHTVMGRIATLATSLEGGKTPIAKEIEHFIHIITGVAVFLGVSFFVLSLILGYGWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMAKKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGTCFDKSSATWASLARVAGLCNRAVFLAEQNNVPILKRDVAGDASESALLKCIELCCGSVKDMREKYSKIAEIPFNSTNKYQLSIHKNIVAGESNHLLVMKGAPERILDRCSTILIQGKEQTLNDELKEAFQNAYEELGGLGERVLGFCHFQLPDDQFAEGFQFDCEEVNFPTENLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLKIPVSEVNPRDAKACVVHGGELKDLSAEQLDDILAHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEEAENDIMKRQPRNPKTDKLVNERLISIAYGQIGMMQATAGFFTYFVILAENGFLPMDLLGMRVDWDNKIMNDMEDSYGQQWTYEHRKIVEFTCHTAFFASIVVVQWADLIICKTRRNSILQQGMKNRILIFGLFEETALAVFLSYCPGMDVALRMYPLKPCWWFCALPYSLLIFLYDEGRRYILRRNPGGWVEQETYY
Protein: L-tryptophan decarboxylase (EC 4.1.1.105) (Psilocybin biosynthesis decarboxylase) (A0A286LEZ8)
Organism: Psilocybe cyanescens
Function: L-tryptophan decarboxylase; part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product. The first step in the pathway is the decarboxylation of L-tryptophan to tryptamine by the decarboxylase psiD. PsiD does not decarboxylate phenylalanine, tyrosine, or 5-hydroxy- L -tryptophan (5-HTP). 4-hydroxy-L-tryptophan is accepted as substrate by psiD as well. The cytochrome P450 monooxygenase psiH then converts tryptamine to 4-hydroxytryptamine. The kinase psiK catalyzes the 4-O-phosphorylation step by converting 4-hydroxytryptamine into norbaeocystin. The methyltransferase psiM then catalyzes iterative methyl transfer to the amino group of norbaeocystin to yield psilocybin via a monomethylated intermediate, baeocystin. 4-hydroxy-6-methyl-l-tryptophancan also be converted the decarboxylase PsiD, kinase PsiK, and methyltransferase PsiM into respectively 6-methyl-norbaeocystin, 6-methylbaeocystin, and 6-methylpsilocybin (By similarity).
Interaction partners:
Sequence:
MQVLPACQSSALKTLCPSPEAFRKLGWLPTSDEVYNEFIDDLTGRTCNEKYSSQVTLLKPIQDFKTFIENDPIVYQEFISMFEGIEQSPTNYHELCNMFNDIFRKAPLYGDLGPPVYMIMARIMNTQAGFSAFTKESLNFHFKKLFDTWGLFLSSKNSRNVLVADQFDDKHYGWFSERAKTAMMINYPGRTFEKVFICDEHVPYHGFTSYDDFFNRRFRDKDTDRPVVGGVTDTTLIGAACESLSYNVSHNVQSLDTLVIKGEAYSLKHLLHNDPFTPQFEHGSIIQGFLNVTAYHRWHSPVNGTIVKIVNVPGTYFAQAPYTIGSPIPDNDRDPPPYLKSLVYFSNIAARQIMFIEADNKDIGLIFLVFIGMTEISTCEATVCEGQHVNRGDDLGMFHFGGSSFALGLRKDSKAKILEKFAKPGTVIRINELVASVRK
Protein: Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (Q02318)
Organism: Homo sapiens (Human)
Function: Cytochrome P450 monooxygenase that catalyzes regio- and stereospecific hydroxylation of cholesterol and its derivatives. Hydroxylates (with R stereochemistry) the terminal methyl group of cholesterol side-chain in a three step reaction to yield at first a C26 alcohol, then a C26 aldehyde and finally a C26 acid. Regulates cholesterol homeostasis by catalyzing the conversion of excess cholesterol to bile acids via both the 'neutral' (classic) and the 'acid' (alternative) pathways. May also regulate cholesterol homeostasis via generation of active oxysterols, which act as ligands for NR1H2 and NR1H3 nuclear receptors, modulating the transcription of genes involved in lipid metabolism. Plays a role in cholestanol metabolism in the cerebellum. Similarly to cholesterol, hydroxylates cholestanol and may facilitate sterol diffusion through the blood-brain barrier to the systemic circulation for further degradation. Also hydroxylates retinal 7-ketocholesterol, a noxious oxysterol with pro-inflammatory and pro-apoptotic effects, and may play a role in its elimination from the retinal pigment epithelium. May play a redundant role in vitamin D biosynthesis. Catalyzes 25-hydroxylation of vitamin D3 that is required for its conversion to a functionally active form.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P17178}; Peripheral membrane protein {ECO:0000250|UniProtKB:P17178}. Note=Post-translationally targeted to mitochondria. All three of the receptor proteins in the TOM complex, TOMM70, TOMM20 and TOMM22 are required for the translocation across the mitochondrial outer membrane. After translocation into the matrix, associates with the inner membrane as a membrane extrinsic protein. {ECO:0000250|UniProtKB:P17178}.
Interaction partners:
- Cytochrome P450 7A1
- Cholesterol 25-hydroxylase
- Cytochrome P450 7B1
- Long-chain fatty acid transport protein 5
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
- Cholesterol 24-hydroxylase
- Aldo-keto reductase family 1 member C4
- 7-dehydrocholesterol reductase
- Adrenodoxin, mitochondrial
- Delta
Sequence:
MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAPGAGPGVRRRQRSLEEIPRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQRQC
Protein: C4 phosphoenolpyruvate carboxylase (C4 PEPC) (C4 PEPCase) (ppcA) (EC 4.1.1.31) (Photosynthetic PEPCase) (P30694)
Organism: Flaveria trinervia (Clustered yellowtops) (Oedera trinervia)
Function: Forms oxaloacetate through the carboxylation of phosphoenolpyruvate (PEP). Catalyzes the first step of C4 photosynthesis.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P27154}.
Interaction partners:
Sequence:
MANRNVEKLASIDAQLRLLVPGKVSEDDKLVEYDALLLDKFLDILQDLHGEDLKEAVQQCYELSAEYEGKHDPKKLEELGSLLTSLDTGDSIVIAKAFSHMLNLANLAEELQIAYRRRIKLKSGDFADEANATTESDIEETFKRLVHKLNKSPEEVFDALKNQTVELVLTAHPTQSVRRSLLQKHGRIRNCLAQLYAKDITPDDKQELDEALHREIQAAFRTDEIRRTPPTPQDEMRAGMSYFHETIWKGVPKFLRRVDTALKNIGINERFPYNAPLIQFSSWMGGDRDGNPRVTPEVTRDVCLLARMMTSNMYFSQIEDLMIEMSMWRCNSELRVRAEELYRTARKDVKHYIEFWKRIPPNQPYRVILGDVRDKLYNTRERSRHLLVDGKSDIPDEAVYTNVEQLLEPLELCYRSLCDCGDHVIADGSLLDFLRQVSTFGLSLVKLDIRQESDRHTEVLDAITQHLGIGSYREWSEEKRQEWLLAELSGKRPLIGPDLPKTEEVKDCLDTFKVLAELPSDCFGAYIISMATSTSDVLAVELLQREYHIKHPLRVVPLFEKLADLEAAPAAMTRLFSMDWYRNRIDGKQEVMIGYSDSGKDAGRFSAAWQLYKTQEQIVKIAKEFGVKLVIFHGRGGTVGRGGGPTHLALLSQPPDTINGSLRVTVQGEVIEQSFGEEHLCFRTLQRFCAATLEHGMNPPISPRPEWRELMDQMAVVATEEYRSVVFKEPRFVEYFRLATPELEFGRMNIGSRPSKRKPSGGIESLRAIPWIFSWTQTRFHLPVWLGFGAAFKHAIQKDSKNLQMLQEMYKTWPFFRVTIDLVEMVFAKGNPGIAALNDKLLVSEDLRPFGESLRANYEETKNYLLKIAGHKDLLEGDPYLKQGIRLRDPYITTLNVCQAYTLKRIRDPNYHVTLRPHISKEYAAEPSKPADELIHLNPTSEYAPGLEDTLILTMKGIAAGMQNTG
Protein: Protein FYV5 (Function required for yeast viability protein 5) (P25585)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in maintaining an adequate ionic strength homeostasis of the cellular aqueous environment, necessary for normal growth rate. Required for survival upon exposure to K1 killer toxin and hence plays a role in cell wall glucan synthesis. Required for dithiothreitol (DTT) resistance. Involved in cell cycle progression.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Secreted, cell wall.
Interaction partners:
- Bypass of stop codon protein 4
- Antisense of depressing factor protein 1
- Silenced mating-type protein ALPHA2
Sequence:
MQYHSALYVYIYVTFTTIPYKEKPDIISICFSMLSFVFDFSVRICSRTLESFSWSLISSSAFKVVSAFSLAGSCVLASRSSVGIIVSLLLFNFSTCNFVLFLSAVLIDLFFCTFLPTPTFLPTPFFFMLHLPIFSLLNALELLYLIIAGLHI
Protein: Pleiomorphic adenoma gene-like 1 (B0QZX4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAPFRCQKCGKSFVTLEKFTIHNYSHSRERPFKCSKAECGKAFVSKYKLMRHMATHSPQKIHQCTHCEKTFNRKDHLKNHLQTHDPNKISYACDDCGKKYHTMLGYKRHLALHSASN
Protein: Juvenile hormone resistance protein (O44118)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAAPETGNTGSTGSAGSTGSGSGSGSGSGSSSDPANGREARNLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQYVFGKSASRRRKKTGLKGTGMSASPVGDLPNPSLHLTDTLMQLLDCCFLTLTCSGQIVLVSTSVEQLLGHCQSDLYGQNLLQITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTSTSASASGSDLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDWRCFTVRLARASTRAEATRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQLIRRSRNNNMLAAAAAVAAEAATVPPQHDAIAQAALHGISGNDIVLVAMARVLREERPPEETEGTVGLTIYRQPEPYQLEYHTRHLIDGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYDCNSDYGESCYRLLSRNGRFIYLHTKGFLEVDRGSNKVHSFLCVNTLLDEEAGRQKVQEMKEKFSTIIKAEMPTQSSSPDLPASQAPQQLERIVLYLIENLQKSVDSAETVGGQGMESLMDDGYSSPANTLTLEELAPSPTPALALVPPAPSSVKSSISKSVSVVNVTAARKFQQEHQKQRERDREQLKERTNSTQGVIRQLSSCLSEAETASCILSPASSLSASEAPDTPDPHSNTSPPPSLHTRPSVLHRTLTSTLR
Protein: Potassium channel toxin alpha-KTx 3.13 (MeuKTx) (P86396)
Organism: Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)
Function: Blocks voltage-gated potassium channels Kv1.1/KCNA1 (IC(50)=203.15 pM), Kv1.2/KCNA2 (IC(50)=8.92 nM) from rat and human Kv1.3 KCNA3/KCNA3 (IC(50)=171 pM) potently. At 2 uM, also blocks Shaker IR and has a moderate effect on rat Kv1.6/KCNA6.
Subcellular location: Secreted {ECO:0000269|PubMed:20713119}.
Interaction partners:
Sequence:
VGINVKCKHSGQCLKPCKDAGMRFGKCMNGKCDCTPK
Protein: Tumor necrosis factor ligand superfamily member 9 (4-1BB ligand) (4-1BBL) (P41273)
Organism: Homo sapiens (Human)
Function: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 9
- Tumor necrosis factor receptor superfamily member 4
- T-cell-specific surface glycoprotein CD28
- CD27 antigen
- CD70 antigen
- Tumor necrosis factor ligand superfamily member 4
- Inducible T-cell costimulator
- T-lymphocyte activation antigen CD80
- ICOS ligand
- Ig-like domain-containing protein
Sequence:
MEYASDASLDPEAPWPPAPRARACRVLPWALVAGLLLLLLLAAACAVFLACPWAVSGARASPGSAASPRLREGPELSPDDPAGLLDLRQGMFAQLVAQNVLLIDGPLSWYSDPGLAGVSLTGGLSYKEDTKELVVAKAGVYYVFFQLELRRVVAGEGSGSVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGLPSPRSE
Protein: Protein phosphatase 6 regulatory subunit 3 (H7BXH2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSFIIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLLASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTSSINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV
Protein: Major facilitator superfamily domain-containing 14C pseudogene (Hippocampus abundant transcript-like protein 2) (Q5VZR4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSVEPPPELEEKAASEPEAGAMPEKRAGAQAAGSTWLQGFGPPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPCRVWWRAPVVPATCGRRMA
Protein: Adhesin P1 (Q93Q04)
Organism: Mycoplasmoides pneumoniae (Mycoplasma pneumoniae)
Interaction partners:
Sequence:
MHQTKKTALSKSTWILILTATASLATGLTVVGHFTSTTTTLKRQQFSYTRPDEVALRHTNAINPRLTPWTYRNTSFSSLPLTGENPGAWALVRDNSAKGITAGSGSQQTTYDPTRTEAALTASTTFALRRYDLAGRALYDLDFSKLNPQTPTRDQTGQITFNPFGGFGLSGAAPQQWNEVKNKVPVEVAQDPSNPYRFAVLLVPRSVVYYEQLQRGLALPNQGSSSGSDSTNQTGAMFGLKVKDATVDSSKQSTESLKGEESSSSSTTSSTSTTQRGGSSNENKVKALQVAVKKKSGSQGNSGDQGTEQVELESNDLANAPIKRGSNNNQQVQLKADDFGTAPSSSGSGTQDGTPTPWTPWLTTEQIHNDPAKFAASILILYDAPYARNRTAIDRVDHLDPKAMTANYPPSWRTPKWNHHGLWDWKARDVLLQTTGFFNPRRHPEWFDGGQTVADNEKTGFDVDNSENTKQGFQKEADSDKSAPIALPFEAYFANIGNLTWFGQALLVFGGNGHVTKSAHTAPLSIGVFRVRYNATGTSATVTGWPYALLFSGMVNKQTDGLKNLPFNNNRWFEYVPRMAVAGAKFVGRELVLAGTITMGDTATVPRLLYDELESNLNLVAQGQGLLREDLQLFTPYGWANRPDLPIGAWSSSSSSSHNAPYYFHNNPDWQDRPIQSVVDAFIKPWEDKNGKDDAKYIYPYRYSGMWAWQVYNWSNKLTDQPLSADFVNENAYQPNSLFAAILNPELLAALPDKVKYGKENEFAANEYERFNQKLTVAPTQGTNWSHFSPTLSRFSTGFNLVGSVLDQVLDYVPWIGNGYRYGNNHRGVDDITAPQTSAGSSSGISTNTSGSRSSLPTFSNIGVGLKANVQATLGGSQTMITGGSPRRTLDQANLQLWTGAGWRNDKASSGQSDDHTKFTSATGMGQQEQSGTSAGNPDSLKQDKISKSGDSLTTQDGNAMEQQEATNYTNLPPNLTPTADWPNALSFTNKNNAQRAQLFLRGLLGSIPVLVNKSGQDDNSKFKAEDQKWSYTDLQSDQTKLNLPAYGEVNGLLNPALVETYFGNTRASGSGSNTTSSPGIGFKIPEQSGTNTTSKAVLITPGLAWTPQDVGNLVVSGTSFSFQLGGWLVTFTDFIKPRAGYLGLQLTGLDASDATQRALIWAPRPWAAFRGSWVNRLGRVESVWDLKGVWADQAQSDSQGSTTTATRDALPEHPNALAFQVSVVEASAYKPNTSSGQTQSTNSSPYLHLVKPKKVIQSDKLDDDLKNLLDPNQVRTKLRQSFGTDHSTQPQPQSLKTTTPIFGTSSGNLSSVLSGGGAGGGSSGSGQSGVDLSPVEKVSGWLVGQLPSTSDGNTSSTNNLAPNTNTGNDVVGVGRLSESNAAKMNDDVDGIVRTPLAELLDGEGQTADTGPQSVKFKSPDQIDFNRLFTHPVTDLFDPVTMLVYDQYIPLFIDIPASVNPKMVRLKVLSFDTNEQSLGLRLEFFKPDQDTQPNNNVQVNPNNGDFLPLLTASSQGPQTLFSPFNQWPDYVLPLAITVPIVVIVLSVTLGLAIGIPMHKNKQALKAGFALSNQKVDVLTKAVGSVFKEIINRTGISQAPKRLKQTSAAKPGAPRPPVPPKPGAPKPPVQPPKKPA
Protein: Phosphatidylglycerophosphate phosphatase PTPMT1 (EC 3.1.3.27) (Protein TYROSINE PHOSPHATASE LOCALIZED TO THE MITOCHONDRION 1) (Putative dual specificity protein phosphatase DSP8) (EC 3.1.3.16, EC 3.1.3.48) (Q9ZQP1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Exhibits phosphatidylglycerophosphate phosphatase activity. Involved in root growth and columella cells organization. May possess protein phosphatase activity (By similarity).
Interaction partners:
- acid phosphatase
- Probable protein phosphatase 2C 10
- Metal ion-binding protein
- Inositol diphosphatase DSP2
- Dual specificity protein phosphatase PHS1
- Inositol diphosphatase DSP5
- Mitochondrial carrier protein MTM1
- Inositol diphosphatase DSP1
- Inositol diphosphatase DSP4
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
Sequence:
MYIKELTETDEEKRERSVEDNVDDGDKAVLVSRGNVIVLTTKRALVGVGARALFYPTLVYNVVRNKLESEFRWWDRVAEFILLGAVPFPSDVPQLKELGVCGVITLNEPYETLVPSSLYKSYCIDHLVIATRDYCFAPSMEAICQAVEFIHRNASLGKTTYVHCKAGRGRSTTIVICYLVQHKNMTPEAAYSYVRSIRPRVLLAAAQWKAVVEYYHVKVLNTQSCLTDATSALIPRNVKQVCSGNVVVFDDGSMVVVTHSDLEGYNDDDSRSRRSVKVNGNELWAAAADLSMVYRVKVVGQAAMARISCLWLGLREDQKLSGKNLSMGGISVDISVY
Protein: SET domain-containing protein (B0G196)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MLNRLQSLKKNENLIKFYFNNNYNNLTRYFCTGGSGGGSDIFSTKNSKDAINSTIRSKEDIEEEIKGFQNAPQIKPKIPVDPASLHLSYSIQIAIQKAYDEFMNGKPEEALKRYYWVLSHTPADYAVRIQRATVLESLSRLDDAIIDCNTVIKNSTEGEILSEAFVIKGICLVRKEKYNEAIVAFEKSLLLIHNPKIVDLKREAEMMLYPDTVIVPNHEDDYEFFNGLSSTLMGNAMVKKSPIHGRGIFATRDIEEEELLFEAPSLLSISTNLAKHKYEKHDDEHCNNCHLSLQPVELQNDREISKSKEFPKIEDTLSRMTNLPLGSISGVCCPNCNEAIFCSSECEAQGMARHRLICSGTPSNVHTNFLNKFYHDISKLDDEERTEYLLMLQVFSLQYTTGGNQDEPLRSMQMDQFLKRLVHTEPSKNHTTSYLSRKDMKIYQSIKGIFSNREITQEIYHRVKSIIRLNAVAFPTSRIKILSEKNPMDELGYSFDFQEIPSQQLASILMQGSFFNHSCEPNVFIATPVVNDKSIRFCTRRPIKKGEELFISYLDGEKLTTEKRRTTLKETYSFICNCQACTSRKTIDFLSILD