wanglab/gogpt-training-data huggingface dataset:
Protein: Protein CBR-MEL-28 (A8XSR2)
Organism: Caenorhabditis briggsae
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein CBR-NPP-11
- Protein CBR-NPP-15
- Nuclear pore complex protein Nup85
- Nuclear pore complex protein
- Protein CBR-NPP-6
- Protein SEC13 homolog
- Nucleoporin NUP35
- Nuclear pore protein
- Protein CBR-NPP-3
- Spindle-defective protein 2
Sequence:
MDNENSSIFQPYSQYDCWRGEKQIILKTSIGCQLPYIVNFKRNTVQIFNIEWERITHSYVFPEGCQLVDVDYFPTEDGKLGILVAVEDPRQSWGSENFVVALAAKEDQPMMTVTHSADIPTKITVIKTLFSCADMSRRANREVLKLYHRLMTWQHVVAIGCKDSQCHLARLTPVEDSASLVVPIHNDRRNLINLMSAFIEGSVLQYTQNDGSYRNYPTAAVYISALALMPRSRTLLVGLSMGGILAASLNPSNQMIFLELRHERLIRKIAPLEPEDDPDKFEYFIAAVDASPRHPVMIQLWRGSFKTLEQVEEDFKYDNPFYLTCLEHKIPFGEKWISVNPIVTEREHWVTTKRRAGHDESALNVSQTFGATSNRNSVLLTYERKKMLTSEDDPNGLPEYIVEGAIFDIDAWYYKRVPGKVSTDGTVLRQCPFLSTIKSNIPSEDVNDIGILAMNATDVSRFSSMISDADQLFYPSALTYERVFVAKNSKIEWMKIQNIQDTIINKCSSKLAFYLNSAEDVSGIIIAAGMVRKNILSGSPNSSAADINYSQLSSDQKVLLNLIVYYGKVEALCGIVSNSDVSETLKTEIADWALHEAVDFKRTISDKMVAIFQGRSHDLSPLAQDAITQGIKLFRVVYEYLKTCSKFLKSSRLHNMAHSMKCMRNHTKLIYQFFVFDIIPVNQERQKTMRDMHSKRKIAAIRNSSSLPIQALIRNMDRLAPNAQFWDGITHSEWYPPTPVDLLESLLCVNLPERMKRELVVQYVVDWVRASGNELNDKQIAMEVIKIMTNQMLEVDLEKIYYVLDQEKNALTDNKAAEEVRALGEKVFSMQREEVSYEKLWGGGVPITVTINKQDLKKFEQRMKLQMEKARLPVLDPESEMLYQVYLFENEKFNAMSSEAIRSNKLLSMFMPGMYKKHFRSLQKSSKEKEIEQTVKTMFERQKMLDEVVEDEDDMVAVVRDQQKRKRKSGTFGGDDDDCSSVSSASFVPPTAKKIQLWKKASEPAVASIPESPDNKNSSITSLVHSGDPHENNEINMLIATPARYYKRPAFEDDDVNEFLSPTRGKEPPLPAQNSILKTAKAVQTGNRGRIRFHESVRKPAEERIEKNEDSAPSKGLTLNFAILEDEEEEETMTTRRSRTMETEKEVEREEEVMEEEEEESHEEDVEQEKEEDECVESEKTFEEQEDFEVLEDTSAPEKMNSLEDTFEPREDDVMPPVDETYKEEEEKEEEEEKDKEEKQEESNGEEVSDGILRSMEVQSDDDVDPIQPEIVEEEVGEDVEKVQEHQEEVGKEEEEQKTEEVQENNDVVEEEKQEELHENPVSVKPKTSDAPVEASSEVQEPEDDRPPSRTTRTKTVQKTPSVKTNVDTEDGPPSTRLRTRSCSIKRDDVASETPRSRRTSVRRSASRTSSVSEQLETVVPSGKTRKSTGRAASVEHPTGSDVSGTPRRRGRPRLSSLTTTPKETRKRENSTEQDDTETPNKRRRGTSRATPMKVIPEDEPSISTANQQEATESSVVTPKKGRGRPRKELANVEEELEEPEEPAVNTSLRRSTRRSQQQ
Protein: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Q95142)
Organism: Bos taurus (Bovine)
Function: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:14561760, ECO:0000305|PubMed:8798640}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:O43924}; Peripheral membrane protein {ECO:0000250|UniProtKB:O43924}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:O43924}.
Interaction partners:
- Phosphatidylinositol polyphosphate 5-phosphatase type IV
- ADP-ribosylation factor-like protein 3
- ADP-ribosylation factor-like protein 2
- X-linked retinitis pigmentosa GTPase regulator
- ADP ribosylation factor like GTPase 13B
- Guanylate kinase
- Inosine triphosphate pyrophosphatase
- GMP synthase
- Adenine phosphoribosyltransferase
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
Sequence:
MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
Protein: Keratin-associated protein 16-1 (A8MUX0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSGSCSSRKCFSVPATSLCSTEVSCGGPICLPSSCQSQTWQLVTCQDSCGSSSCGPQCRQPSCPVSSCAQPLCCDPVICEPSCSVSSGCQPVCCEATTCEPSCSVSNCYQPVCFEATICEPSCSVSNCCQPVCFEATVCEPSCSVSSCAQPVCCEPAICEPSCSVSSCCQPVGSEATSCQPVLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCPTPTCSVTSSCQAVCCDPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCRPLSCSPGSSASAICRPTCPRTFYIPSSSKRPCSATISYRPVSRPICRPICSGLLTYRQPYMTSISYRPACYRPCYSILRRPACVTSYSCRPVYFRPSCTESDSCKRDCKKSTSSQLDCVDTTPCKVDVSEEAPCQPTEAKPISPTTREAAAAQPAASKPANC
Protein: Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (IL-12 subunit p40) (Q9R278)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU281113}.
Interaction partners:
Sequence:
MCHQKLTFSWFAMVLLVSPLMAMWELEKDVYVVEVDWRPDAPGETVTLTCDSPEEDDITWTSDQRRGVIGSGKTLTITVREFLDAGQYTCHRGGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVHRNTDLKFNIKSSSSSPESRAVTCGRASLSAEKVTLNQRDYEKYSVACQEDVTCPTAEETLPIELVVEAQQQNKYENYSTSFFIRDIIKPDPPKNLQVKPLKNSQVEVSWEYPDSWSTPHSYFSLKFFVRIQRKKEKTKETEEECNQKGAFLVEKTSAEVQCKGANICVQAQDRYYNSSCSKWTCVPCRGRS
Protein: DASH complex subunit duo1 (Outer kinetochore protein duo1) (O74372)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P53168}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P53168}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:P53168}. Cytoplasm, cytoskeleton {ECO:0000305|PubMed:20624975}. Note=Associates with the mitotic spindle and the kinetochore (By similarity). In the cytoskeleton, localizes to cortical microtubules (Probable). {ECO:0000250|UniProtKB:P53168, ECO:0000305|PubMed:20624975}.
Interaction partners:
- DASH complex subunit dad3
- DASH complex subunit spc19
- DASH complex subunit dam1
- DASH complex subunit ask1
- DASH complex subunit dad2
- DASH complex subunit spc34
- DASH complex subunit DAD5
- DASH complex subunit dad4
- DASH complex subunit dad1
- Kinetochore protein ndc80
Sequence:
MTSELQQELQILRSFNYTIEKLTDGLSASKEKIKSFETSINNSNRLIQLWSSVLSQTEHTQNLILNSDWKGLSFDNEELERLQHQKMLQIQAEEQRKIELQQEQERLEQERRQKEEAIALQKQQQQRLLRSKDPKVRPARRAASSYVPSRPSHVPRSSSMNVRSRVSMATTSNPNSLRTPSSSFASHRQSAIPKSATSSAPTIPTSNLPSVASSIPNNGLNSSNRKSIISKTSSRLRPPSRVSNVPSVPQHPSTRSRTSTRETTQPPFTTNPSNRSKRTTLR
Protein: Cell wall protein CWP2 (Low pH resistance protein 1) (P43497)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the cell wall.
Subcellular location: Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP) found in young daughter cells.
Interaction partners:
- Cell wall protein SED1
- Covalently-linked cell wall protein 12
- Alpha-agglutinin
Sequence:
MQFSTVASVAFVALANFVAAESAAAISQITDGQIQATTTATTEATTTAAPSSTVETVSPSSTETISQQTENGAAKAAVGMGAGALAAAAMLL
Protein: Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial) (Q8CCM6)
Organism: Mus musculus (Mouse)
Function: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Subcellular location: Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit Tim23
- Mitochondrial import inner membrane translocase subunit TIM16
- Mitochondrial import inner membrane translocase subunit Tim17-A
- Mitochondrial import inner membrane translocase subunit Tim17-B
- Mitochondrial import inner membrane translocase subunit TIM44
- Reactive oxygen species modulator 1
- Mitochondrial import receptor subunit TOM22 homolog
- Mitochondrial import inner membrane translocase subunit TIM14
- DnaJ homolog subfamily C member 15
Sequence:
MICAFLRVVQHAEKLHGSLGRQLLPHFVFTKACFKTQPLRWGLREQKITVQPRTVLRFTQKTFWTQGPDPRKAKEDSTKQVSIRRNQREETGVSMSQKVREAGRDVSYLIVVLFGVGLTGGLLYAIFKELFFSSSPNIIYGKALGKCRTHPEVIGVFGEPLKGYGEMSRRGRRQHVRFSEYVNNGLKRIRVKFYIEGSEPGKQGTVHAEVEENPGSGQFEFRYIFVEVTPTRSIIVEDNRSEQS
Protein: SD23516p (Q86PC7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGGSLELAGGRRTRSSTRGTPTRAAEAVTPPPSKKARTSPASATKASAGKGRGARKLDVGADEPEPELEKEKEKVQTSVKGKGAVKKDKKEVKKQEKATEKYAPEEAKEDVAEAKEEDASPAGVQDQPDGVENLHSVAEAKQNHVDEVKPISEEPGNSSEEVPKAEEPLKSSGETSENGAATETAAAPKEPASVMDVDEDETLVENTPSANKEKALDDEKEPEQKSEEHAAAVLESKEQNEPAKEPTPEPMEVDGSSKGSSDTAQVDTPAIENVSAAPETEAAAKTTESSNDVVEVATEGKETVLEVPAAEPKEAESTVESAEELTETSTVVVTEPKEAASSEEEPSKVVDSAEPKEAESNTDESATPVPIDVSTAPASNDVSKPLEIDTTLVKTADSPAKEPQEICEVKKAEINVNGEPKIVNSSAEVGENAAPKVCN
Protein: Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) (P98155)
Organism: Homo sapiens (Human)
Function: Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism. Binds also to a wide range of other molecules including Reelin/RELN or apolipoprotein E/APOE-containing ligands as well as clusterin/CLU. In the off-state of the pathway, forms homooligomers or heterooligomers with LRP8. Upon binding to ligands, homooligomers are rearranged to higher order receptor clusters that transmit the extracellular RELN signal to intracellular signaling processes by binding to DAB1. This interaction results in phosphorylation of DAB1 leading to the ultimate cell responses required for the correct positioning of newly generated neurons. Later, mediates a stop signal for migrating neurons, preventing them from entering the marginal zone (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:23701949, ECO:0000269|PubMed:34929721}; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.
Interaction partners:
- Reelin
- Apolipoprotein E
- Disabled homolog 1
- Proprotein convertase subtilisin/kexin type 9
- Low-density lipoprotein receptor-related protein 8
- Clusterin
- Lipoprotein lipase
- Thrombospondin-1
- Cholesteryl ester transfer protein
- Plasminogen activator inhibitor 1
Sequence:
MGTSALWALWLLLALCWAPRESGATGTGRKAKCEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSELATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPSGYNVEENGRDCQSTATTVTYSETKDTNTTEISATSGLVPGGINVTTAVSEVSVPPKGTSAAWAILPLLLLVMAAVGGYLMWRNWQHKNMKSMNFDNPVYLKTTEEDLSIDIGRHSASVGHTYPAISVVSTDDDLA
Protein: Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein) (Q54EW8)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Mitochondrion matrix {ECO:0000305}.
Interaction partners:
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
- 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
- Pyruvate dehydrogenase complex subunit homolog DDB_G0271564
- Aminomethyltransferase, mitochondrial
Sequence:
MLRINRISNLRTFGQRFFSTEQQDVVVIGGGPGGYVAGIKAGQLGMKVTVVEKRGKLGGTCLNVGCIPSKALLNASHLYEEATTKMSKYGVKCSGVELDLGAMMQYKDKSVSGLTSGIEGLFKKNKVKYDKGFGKITGPNTVEVTLNDGSVKTIETKNIVIATGSEVTSLPNVNIDEESIISSTGALALKSVPKKLIVIGGGVIGLELGSVWSRLGSETTVVEFTNRIAAGADGEVAKKFQKSLEKQHMKFHLETKVTSVVKKSDGKVTVTVEQVGAGGFTGTLEADAVLVSVGRRPNTSGLGLESVGIPTDKAGRVEVGDHFNTKVPSIFAIGDAIRGPMLAHKAEEEGIAIIEQIHNGGGHVNYGAIPSIIYTHPEVAWVGKTEEELQKEGIQYNIGRFPFVANSRAKTNDDVEGFVKFLAAKDSDRVLGAHIMGTNAGELIGECVLAMEYGASCEDIARTCHGHPTLSEAVKEAAMDAYDKPIHM
Protein: Gibberellin 20 oxidase 1 (OsGA20ox1) (EC 1.14.11.-) (GA 20-oxidase 1) (Gibberellin C-20 oxidase 1) (Os20ox) (P93771)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Key oxidase enzyme in the biosynthesis of gibberellin. Catalyzes the conversion of GA12 and GA53 to GA9 and GA20 respectively, via a three-step oxidation at C-20 of the GA skeleton (Ref.1).
Interaction partners:
- Ent-kaurenoic acid oxidase
- Gibberellin 2-beta-dioxygenase 3
- Gibberellin 2-beta-dioxygenase 6
- Gibberellin 2-beta-dioxygenase 5
- Os02g0630300 protein
- Gibberellin 20 oxidase 3
- Os05g0514600 protein
- Gibberellin 2-beta-dioxygenase 1
- Gibberellin 3-beta-dioxygenase 1
- Gibberellin 2-beta-dioxygenase 2
Sequence:
MSMVVQQEQEVVFDAAVLSGQTEIPSQFIWPAEESPGSVAVEELEVALIDVGAGAERSSVVRQVGEACERHGFFLVVNHGIEAALLEEAHRCMDAFFTLPLGEKQRAQRRAGESCGYASSFTGRFASKLPWKETLSFRYSSAGDEEGEEGVGEYLVRKLGAEHGRRLGEVYSRYCHEMSRLSLELMEVLGESLGIVGDRRHYFRRFFQRNDSIMRLNYYPACQRPLDTLGTGPHCDPTSLTILHQDHVGGLEVWAEGRWRAIRPRPGALVVNVGDTFMALSNARYRSCLHRAVVNSTAPRRSLAFFLCPEMDTVVRPPEELVDDHHPRVYPDFTWRALLDFTQRHYRADMRTLQAFSDWLNHHRHLQPTIYS
Protein: Is a member of the PF|00364 Biotin-requiring enzymes family (Single hybrid motif superfamily protein) (Q8VZ68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable UDP-3-O-acylglucosamine N-acyltransferase 2, mitochondrial
- Probable tetraacyldisaccharide 4'-kinase, mitochondrial
- Probable UDP-3-O-acylglucosamine N-acyltransferase 1, mitochondrial
- Probable UDP-3-O-acyl-N-acetylglucosamine deacetylase 5, mitochondrial
- Probable UDP-3-O-acyl-N-acetylglucosamine deacetylase 2, mitochondrial
- Probable UDP-3-O-acyl-N-acetylglucosamine deacetylase 3, mitochondrial
- Probable lipid-A-disaccharide synthase, mitochondrial
- Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, mitochondrial
- At5g19070
- Probable UDP-3-O-acyl-N-acetylglucosamine deacetylase 1, mitochondrial
Sequence:
MNSCSLGAPKVRIFATNFSRLRCGNLLIPNNQRLFVDQSPMKYLSLRTTLRSVKAIQLSTVPPAETEAIADVKDSDETKSTVVNTHLMPKSSEVEALISEITDSSSIAEFELKLGGFRLYVARKLTDESSPPPQQIQPVVAASATPEGVHTNGSATSSSLAITKTSSSSADRPQTLANKAADQGLVILQSPTVGYFRRSKTIKGKRTPTICKEKDIVKEGQVLCYIEQLGGQIPVESDVSGEIVKILREDGEPVGYNDALITVLPSFPGIKKLQ
Protein: Ribonucleoside-diphosphate reductase small subunit (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (P42521)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Ribonucleoside-diphosphate reductase large subunit
- Guanylate kinase
- Nucleoside diphosphate kinase, cytosolic
- Nucleoside diphosphate kinase, mitochondrial
- Probable nucleoside diphosphate kinase DDB_G0292928
- Probable adenylate kinase B
- Adenylate kinase
- UMP-CMP kinase
- Thymidylate kinase
- Guanosine-3',5'-bis
Sequence:
MEEINKKDTFIEPILKENKDRFVLFPIKYPDIWRMYKKALASHWVAEEIDLGNDNVDWEYKLTDNERHFISHVLAFFAASDGIVNENLATRFMSEVQIPEARCFYGFQIAIENIHSETYSLLIETYIKDKQTKDKLFNAIETIPCIKKKAEWALRWINDSDSFAERLVAFAAVEGIFFSGSFCSIFWLKKRGLMQGLTFSNELISRDEGLHCDFACLLYTKLQRKLDPKVIEKMIRDAVECEKEFICESLPVDLIGMNSRSMSQYIEFCADRLVVSLGYKKIFNSSNPFEWMEMISLQRKSNFFEGKVAEYAKTGVAIQGNNQQKNNQSRTLVLDEDF
Protein: nitric oxide dioxygenase (EC 1.14.12.17) (Q5AX11)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MSLSPEQIQLIKATVPVLQEHGTTITKVFYDNMLTAHPELKTVFNVSNKVHGHQPQALAGALFAYASYIDNLGVLSPAVERICHKHASLAIQPDGYQIVGKFLLEAMGQVLGDALTPPLLEAWAAAYWQLANIMIGKEAELYKSADGWTDFRDFRVARKEPESDVITSFYLEPVDGKPLPSFLPGQYVSIQVQVPQLNHAQCRQYSLSDQPKPTYYRISVRKDLGLDASDPSAPAHPGYVSNILHDNINVGDIVKLTHPYGDFHLTDAAASSPLVLISAGVGLTPMTSMVNTLRTAESNTRPVHFIHGAHTSASRAFQAHLQSLPNLKTTYFLTAPTESDKQGENYTYKGRVDLSKIADEDLFLGDKQTEYYICGPTAFMLDTQKALVARGVDQSRVHMELFGTGGVPAA
Protein: Sex-determining transformer protein 2 (Cr-tra-2) (Q9NIW4)
Organism: Caenorhabditis remanei (Caenorhabditis vulgaris)
Function: Plays a major role in controlling sexual cell fates. Promotes female development in XX animals where it sequesters one or more of the FEM proteins to the membrane thereby freeing the tra-1 protein (a putative transcription factor) to enter the nucleus and promote female development. In XO animals it acts as a receptor for her-1 which prevents it from binding to FEM proteins thereby repressing the activity of tra-1. Negatively regulates male development when bound to fem-3 and is required together with tra-1 for promoting spermatogenesis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSLRSNKLLVAAVIFTVVTFGLLLTSSIFNNKTTTSLTYGGILPKFGQRIIEKKSNEEYIIEKIEHTQKDGEDVRSTRYLTHHSYLLRNLAKMEVKHHGKDFSINDICYKPHNAIFETTFAPENIDKLPNYLQRLILEAQRLSPCLIVTPLNCYHDSYRIHSEMSKWNTSNVTNFLNRKLRNSYIDAIGESEERPYIKSTYGPDLIKEWAHLMFKLPSKQTSSFSKKDLSSKIELWLSSIESKTNLTELGRPSEVDNYFDICTSMQQVHDFDERKRKFGLYDDDDEFLIGLDCVENKTKFIEWIQERELRGVSKPFNPNQQCDGIFKNSEGLEFFYGTRSFGNNTAPFDKMKTEIGLMTPEQILTTMLHSDFVNGFESIWTIERAQELLDDFRLAIRQEVKRFNENRSSLKIGIDTRVVQREESNETELEISSNLDSVVYFILFIRCVLLIFFAFFAWSVNPLRSAVMFLVRDALTSLLFSILCKSDGQIELNSELLGYIILLTIVNTYLTTRVSWYKDRNETCIQRAKDFPSRSNFSLLFSIDSLRENCDSRQLQYALAKLSKYLTALDTYSTETFMQLPNYWPFISILFVPITGCYWYFVDINLPKISVVLLPSFIVATIEQRQVEKSLLKERKAKKEFQKVQKKKMEKFLSDGAVDRLLSGNSESVEDKKLYKSKDCVIHKESAGRLYELSRSSYDVSKIMAYPNQRVRDFRFDALGCYFWLMKLKSAGILLYGSAVLFVLLSVAVMLIPIQRTSLQKDMNNEVYFGFSINNMSSDWANINKNLHAFNSEIDSIQSLQTISNWKKGFDRFEGRFYKNSSRISDANDYVEWMNQEPINWSVMAPLTRISPKFGIPSPFKFRFRYQIEVNNNESEVIDTVQRIDTLLTKYKGTLSSPIVDGVLYEYYHGNAAVWNSFVFNELLASGILSAFFALIVVIFSITPSISSVLIFSFFVIGSRLEIAAVISLFSLDNQQLYTDSAVLVGFLVAWAPFYELSLFRRRLLYKLKTRCTPELSSGKRIRPPFTKAVDTAQVFAIVLAASLIIAVVAGVVPEFQKFFWPTVILIVVQLVAFGNSIAVLVATNQMFEREVRNFLDNEFELGNGTTAGQVCHMAQKLIPPKYDIPIPMNDFHIRPTNMSKFYAPPPAKKRAKQTNNETDPEKKEDEPGTSNANNVSQEEAAHRLAILPWHFVLGGIPVDLTTRSDQIINGPFIGISSDAMRTHEINSELEDQDDYSSESSVEDVESDPAPEEEIKYHEENMLHMIEKVQKDAAEKEAKEKVHQVESAQRRAPNFDDPNVAGPSHRYQRNEERISTDIVPADPPREIPANPVPPPTHVLVQRAPRPHEMPPVIDRTIPRDPRTEPPNLQECIQQNDDPSLPPHPRRHQYPDHYGRAMISYCEDVYWTYNDGRLPPNVAMPPRPFDWHYRRVAPPEDFNYVPPPGQPSIPIPAEAMALREERARAHREQEQRDNSQSPSPSPEPGL
Protein: Galactinol synthase 1 (GolS-1) (SlGolS1) (EC 2.4.1.123) (Q947G8)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants. May promote plant stress tolerance.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- DNA polymerase delta small subunit
- galactinol--sucrose galactosyltransferase
- galactinol--sucrose galactosyltransferase
- galactinol--sucrose galactosyltransferase
- galactinol--sucrose galactosyltransferase
- galactinol--sucrose galactosyltransferase
Sequence:
MAPEFESGTKMATTIQKSSCAYVTFLAGNGDYVKGVVGLAKGLIKAKSMYPLVVAILPDVPEEHRMILTRHGCIVKEIEPLAPSLQSLDKYARSYYVLNYSKLRIWEFVEYSKMVYLDGDMQVFENIDHLFELPDKYLYAVADCICDMYGEPCDEVLPWPKELGPRPSVYFNAGMFVFQPNPSVYVRLLNTLKVTPPTQFAEQDFLNMYFKDVYKPIPYTYNMLLAMLWRHPEKIEVNKAKAVHYCSPGAKPWKYTGKEEHMDREDIKMLVKKWWDIYNDTTLDHKAQGSTVEANRLRGAAFSDTNISALYITSPSAA
Protein: Protein virC2 (P07166)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Interaction partners:
Sequence:
MGIRKPALSVGEARRLAAARPEIVHPSLPVATQNSTLPQPPENLDEEDRRPAPATAKRCHSSDQQSMLTVDALSSTTAPEKIQVFLSARPPAPEVSKIYDNLILQYSPSKSLQMILRRALGDFENMLADGSFRAAPKSYPIPHTAFEKSIIVQTSRMFPVSLIEAARNHFDPLGLETARAFGHKLATAALACFFAREKATNS
Protein: Calreticulin-1 (O04151)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity).
Subcellular location: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
Interaction partners:
- Endoplasmin homolog
- Calnexin homolog 1
- UDP-glucose:glycoprotein glucosyltransferase
- Calnexin homolog 2
- Heat shock 70 kDa protein BIP3
- Calreticulin-2
- Heat shock 70 kDa protein BIP1
- Protein disulfide isomerase-like 1-1
- Heat shock 70 kDa protein BIP2
- Calreticulin-3
Sequence:
MAKLNPKFISLILFALVVIVSAEVIFEEKFEDGWEKRWVKSDWKKDDNTAGEWKHTAGNWSGDANDKGIQTSEDYRFYAISAEFPEFSNKDKTLVFQFSVKHEQKLDCGGGYMKLLSDDVDQTKFGGDTPYSIMFGPDICGYSTKKVHAILTYNGTNHLIKKEVPCETDQLTHVYTFVLRPDATYSILIDNVEKQTGSLYSDWDLLPAKKIKDPSAKKPEDWDDKEYIPDPEDTKPAGYDDIPKEIPDTDAKKPEDWDDEEDGEWTAPTIPNPEYNGEWKPKKIKNPAYKGKWKAPMIDNPEFKDDPELYVFPKLKYVGVELWQVKSGSLFDNVLVSDDPEYAKKLAEETWGKHKDAEKAAFDEAEKKREEEESKDAPAESDAEEEAEDDDNEGDDSDNESKSEETKEAEETKEAEETDAAHDEL
Protein: Iodotyrosine deiodinase (EC 1.21.1.1) (Halotyrosine dehalogenase) (E7FDV5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the dehalogenation of halotyrosines such as 3,5-diiodo-L-tyrosine. Likely to also catalyze the dehalogenation of other halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine and 3-iodo-L-tyrosine (By similarity).
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Riboflavin kinase
- Methionine aminopeptidase 1D, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Corrinoid adenosyltransferase MMAB
- Succinyl-CoA:glutarate-CoA transferase
- Alpha-methylacyl-CoA racemase.
- Slc5a5 protein
- Pterin-4-alpha-carbinolamine dehydratase
- Cytochrome c oxidase subunit 3
- Pendrin
Sequence:
MAVFSSLTPVFVAVLCVIIGFLFKNSQRKESRSKQKPSDQTARPWVDEDLQDDTEISTKDNEENNEDWMDTTDEENLPHVPYSPVQYSVSEMLDRSERFYTLMNLRRSVRFISPEPVPKEVIDNVIRTAGTAPSGAHTEPWTFVVVSDTDVKHRIREIIEEEEEINYKQRMGNKWVQDLKRLRTNWVKEYLDVAPYLILVFKQAYGILPSGKKKTHYYNEISVSISCGILLAALQNAGLVTVTTTPLNCGPQLRSLLQRPANEKLLMLLPVGFPASDAKVPDLKRKDLNDIMVLV