wanglab/gogpt-training-data huggingface dataset:
Protein: Probable transcription factor TDA9 (Topoisomerase I damage affected protein 9) (Q04545)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-binding protein that acts probably as a transcription factor.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Topoisomerase I damage affected protein 4
Sequence:
MSSEEFKGLPIKRDISSTIYADRPPALSAPPCVGATGNDKIQVLPIPKKSRTIKTDKPRPFLCHICTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCFARRDLVLRHQHKLHSALVSKESINSKDKTEIDAINDKNIIQIQGNKQTILPTPSNPLAKTAVQLKKAAKEKKNGKQGKLDLSPSYGANNHSTDVSPSVGNSSTPAVIEETDSSSHFPLPDTNIPTKSKRHASFSASSAFTYSSDNFQKLHQQAKSDFDELQESIPHQVGFSTPQLTAQQLIENAIESGVVDLETLDLPPFLSLDGLPPASSSAAVAASEQIDICPSSATDTISGANSTPNQAATAPPFQLPIARESSSLFLANTPYLSDFLTMGSSYGGSGGFAKSITADPSLDYFNYKNHSHPDSRHNNSSSGINYSNNKNNNESIEKSQNNSNVINETIDHTDIHAHHADAHDDSFIESEEWLSKFIMDSQIDNDLKLNINHFNDIGFNNLHPQNPTTHSEPRNMHNENRDMHRSASKFQSVSENISPREQMSLFKTKQNKAISKFLSDEKIPSTASPSSSASPVQFDKKNVDINEFLLDESVSNLFTTRQIDLFKKNVNLYSPLFQNQKDAVSSTSLTPSLTTQTATTQSGPGWTDSSQKLTFFTEQLRNLIIKENNLKSNLFPTVDELNHYVDLYQVEFHKYFPFIHLYSIIPSSENYPLVISISMIGALYGFHSTHALLLSKIARTRVRMFLENTRSNHDKTPIWLMQSLVLLTFTSIFSNDMNAFRTVNTQIMILVQLIKISKLNYPLENFIKPPIESDHVLEYQDNPAVLNQFKAQYNTREQINRNFKYFILAQSRIRICHIVLLISNLFKSLVDFDCCFHSIDLKCGVPCYNEVLFFCENSRTWNENLTRFNIVLDSKFSLIEVSNGESNYEKCLMYLSNGNPYLYKNAKISFKTLLSLLISIHEKINIERDALKDSYESDFHAKNVQWRMHSRPLVATMLKHWELLYIKNGGILALSDENLPIINTNPSFRLIIPLYFFAKLRKCLDIAPTLRCIWNQDWNSMNSSLEKVCYERESLREATEYAVSVITFWIDTVSVMKGKSTQTPIFTITCIFVSILVIAGYMRRLEDFAQNKNSDCMIGSLKSTDRILWLKAFKTLKRIESHLSEREYKLQTFAEFLRVPDNGSLDIESLDSSLIENTLNSHDVTNQALDIITRTRLSSRTLYCGARILGDTPVWPVSLLFAHALQSRAIYNINHRKSVNSV
Protein: Nished (O42394)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
NSRQDGILYSHEQTLARPACCSCSQLLDGANKGGFLHRLASKPPAPSDPQTSADSSALSGQERGGAGEAAGLAEQGAGLQPHSLCTCSSHRAFLQPLSPPHTSAQLGSGLGASTAAPSGGEGSVPRGHFCHLPGDGTLTAHPAHLTSTLPKHYSKRKNLPGRAGLGREQFLCPAARRGAGIPQLGHRASGTPRPSPALRASSCSV
Protein: Transcription factor protein (Q4H3A1)
Organism: Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Interaction partners:
- Stress-activated protein kinase JNK
- BZIP domain-containing protein
- Transcription factor protein
- Transcription factor protein
- Transcription factor protein
- non-specific serine/threonine protein kinase
- histone acetyltransferase
- COP9 signalosome complex subunit 5
- Transcription initiation factor TFIID subunit 12
- Transcription factor protein
Sequence:
MEVTFYHDDPASRITYDLHSSPGSVESASSTDGGPVSAISTVPPPYSRHQYDHEFNKTAVLKGMSLNLSDNYSRQSLGKANSAITSSAISSTGYHQPNVVTNSYEQIQSSIVPASSSSLSVSIPEHGSLNAATLSTPDLVNMLKVGSPDFDRMLVHSSQANTQNNSQFFQRNATQEQEIYAQGFVRELERLKSHGSNPDLAAASPHSAGSSTTETPQPSVITSGVMSHQHYAPESYYTREQLHDIPTTSGLGGTVHHVGNPIHLAQQPPMAYMPHLKEESPQTVPIGSSPPVSPINMDHQELIKSERKRLRNRVAASKCRKRKLERISRLEDKVNNLKNQNLELTSSANLLRQQVAELKSKVMTHVNSGCQLMMSQQQVTF
Protein: Monocopper oxidase-like protein SKU5 (Skewed roots) (Q9SU40)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be a monocopper oxidase of unknown specificity. Involved in directional growth processes, possibly by participating in cell wall expansion.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:12119380}. Cell membrane {ECO:0000269|PubMed:12119380, ECO:0000269|PubMed:15060130}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:12119380}; Extracellular side {ECO:0000269|PubMed:12119380}. Note=Partially soluble and located in the cell wall.
Interaction partners:
- Auxin-binding protein 1
- Late embryogenesis abundant
- Phosphatidylinositol-glycan biosynthesis class X-like protein
- AT2G44210 protein)
- Protein SPIRAL1
- Early nodulin-like protein 17
Sequence:
MDLFKILLLVFFVNISFCFAADPYSFYNFEVSYITASPLGVPQQVIAINGKFPGPTINVTTNENLVVNVRNKLDEGLLLHWNGIQQRRVSWQDGVLGTNCPIPPKWNWTYEFQVKDQIGSFFYFPSLHFQRASGGFGSFVVNPRAIIPVPFSTPDGDITVTIGDWYIRNHTALRKALDDGKDLGMPDGVLINGKGPYRYNDTLVADGIDFETITVHPGKTYRLRVSNVGISTSLNFRIQGHNLVLAESEGSYTVQQNYTSLDIHVGQSYSFLVTMDQNASSDYYIVASARVVNETIWRRVTGVGILKYTNSKGKAKGQLPPGPQDEFDKTFSMNQARSIRWNVSASGARPNPQGSFKYGSINVTDVYVLRNMPPVTISGKRRTTLNGISFKNPSTPIRLADKLKVKDVYKLDFPKRPLTGPAKVATSIINGTYRGFMEVVLQNNDTKMQSYHMSGYAFFVVGMDYGEWTENSRGTYNKWDGIARSTIQVYPGAWSAILISLDNPGAWNLRTENLDSWYLGQETYVRVVNPDENNKTEFGHPDNVLYCGALSKLQKPQKVSSSASKSIGFTSLSMVVMALVMMMMLQH
Protein: Cytochrome c oxidase subunit 12, mitochondrial (Cytochrome c oxidase polypeptide VIb) (O94581)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q01519}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q01519}; Intermembrane side {ECO:0000250|UniProtKB:Q01519}.
Interaction partners:
- Cytochrome c oxidase subunit 2
- Cytochrome b-c1 complex subunit 9
- Cytochrome c oxidase subunit 13, mitochondrial
- Cytochrome b-c1 complex subunit 7
- Cytochrome c oxidase subunit 6, mitochondrial
- Cytochrome c oxidase subunit 4, mitochondrial
- Cytochrome c oxidase subunit 3
- Cytochrome b-c1 complex subunit 10
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
Sequence:
MSEQEDQEAPKQFTFGTVGFDARFPNTNQTKHCFQSYIDYFRCIKAKGEDFVPCKQFWHAYQSLCPMEWVERWDEQRENGTFPAPI
Protein: Transaldolase (EC 2.2.1.2) (Q93092)
Organism: Mus musculus (Mouse)
Function: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. Not only acts as a pentose phosphate pathway enzyme, but also affects other metabolite pathways by altering its subcellular localization between the nucleus and the cytoplasm.
Subcellular location: [Isoform 1]: Nucleus {ECO:0000269|PubMed:27703206}. Cytoplasm {ECO:0000269|PubMed:27703206}. Note=Shuttles between the nucleus and the cytoplasm. Actively transported into the nucleus in an importin alpha/beta-dependent manner (PubMed:27703206). Exported into the cytoplasm by CRM1 (PubMed:27703206). {ECO:0000269|PubMed:27703206}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:27703206}. Note=Imported into the nucleus when incorporated in isoform 1/isoform 2 homodimer. {ECO:0000269|PubMed:27703206}.
Interaction partners:
- Transketolase
- Transketolase-like protein 1
- Transketolase-like protein 2
- Glucose-6-phosphate isomerase
- 6-phosphogluconate dehydrogenase, decarboxylating
- Triosephosphate isomerase
- GDH/6PGL endoplasmic bifunctional protein
- Fructose-bisphosphate aldolase A
- ATP-dependent 6-phosphofructokinase, muscle type
- Fructose-1,6-bisphosphatase 1
Sequence:
MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGVGKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNSKLAPALSVKAAQTSDSEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK
Protein: Uromodulin-like 1 (Olfactorin) (Q5DID3)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000269|PubMed:16026467}; Single-pass type I membrane protein {ECO:0000269|PubMed:16026467}.
Interaction partners:
Sequence:
MMSRTVRLVLLALACTVDLSQASGFTENGLSLLSYQLCSYPVTRSVQKLQAVQTSHTAYVYCGGWIPWKKCPKTVYRTQYLAMDVPESRNVTDCCAGFEQLGLYCVLSLNRSREFASRPGVCPTAEAEPLSPSCSLDTDCSGLQKCCSWPGGRHCVSPTPTGTEKSMVSWYNVTVLVKVGFEDLQREDPGLRNHTRLLYSLVTSALQPLNPAVHYLTSTGGKDTFTTVSWLLMGFPRLMTVANVSVMLDDMVNRVYEVVSIQVQDVNECLHSELQACSVREQCRNLEGSYQCVSSQRLNHTDEDCPPIRDFVALNVTSSSFHVSWSLNSTQNYNFHIQVYKGKEILRSAWTRGHTMAVSDLEAGVLYRVRTSYLGCGANVSATLVVKTDAQVFQVTIRIMDRNLTEQILDCSSGEFWNFSRQLFHEVQNSFPQAISDLYRQGRLRMQIVSLQAGSLVVTLRLTLQDPDFSVGVHTLTPMLPVLSVSNVFQVDQQRTFVQDWDECAHSSEHDCHPSARCINLEGSYTCQCLTARDASPSRAGRVCEGDMVIPTGDELSVTTKVTVPAASTGITTFGPETLTESLSSKHPRSTPARSQTWTPVPPSVRDGGSIVRQDRNSTGQGQTHGTHQGTTDAPLHTTRESQELITKDPPFLTATTTGYVVWHSSPTWKTPPNSTRLQNEDPRSSSFPGPPSAPTDVTPESPACVPGPIGKVTVSNVTSTSFSLEWPADIRLSPAFHLTLVSPRGPAMTMETQNNNVTLSGLEWGTLYLVEIVAKVCGKEGARTQLKVRTVAQKLAGNVRITSMQYSESFLNTSSREHREFVELFFRTVRDSLPATLRQHMDAGRIRVDIINITNGSIVVEFNLLMTADLDVREVSAGFLNALQNTSMLEVVRGKTFMQDYNECDMKEDDCAPGTCRNTFGSFTCSCDEGGPDSQVEYSGRSCDGDPSGNMTQTPGSEWSPTPAGTRGVPVPIASSTAQDLPLRLNLMDAVSVSCEIETVIITIQKRFLQQAAIPEASLYLGEPSCNVSRSNSTHVFLVAGWGECGTILQSNMTTTVVTTTLRNNLSPEGVIHHPQFLSPIHCAFQNDVLTSSGYTPQWGVYTVIEDLHGTGNFVTEMQLYIGDSPIPQNYSVSASDEIKIEVGLHRQKSSLKVVLTECWATPSSNAKDPVTFSFINNSCPVPNTYTSVIQNGHSSKAQFKLRIFSFINNSIVYLHCKLRVCMENPRNSCRISCNDFRSLRSSEALHQMTWGPLHRTEGAQACTKPVLGTGYIILLAAAALLVVAGATTLLILRYQRVRQKYNLRIQTDDFSYQVFSQ
Protein: Adhesin P1 (Attachment protein) (Cytadhesin P1) (P11311)
Organism: Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
Function: The protein is the major adhesin mediating the attachment of this mycoplasma to respiratory epithelium.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20199607}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, attachment organelle {ECO:0000269|PubMed:20199607}. Cell surface {ECO:0000269|PubMed:20199607}. Note=Found on the cell surface, including in the tip (attachment) organelle. {ECO:0000269|PubMed:20199607}.
Interaction partners:
- Mgp-operon protein 3
- Bifunctional oligoribonuclease and PAP phosphatase NrnA
- Cytadherence high molecular weight protein 1
- Cytadherence high molecular weight protein 3
- P30 adhesin
- Uncharacterized protein MPN_143
- Proline-rich P65 protein
- Cytadherence high molecular weight protein 2
- Chaperone protein DnaK
- UPF0134 protein MPN_138
Sequence:
MHQTKKTALSKSTWILILTATASLATGLTVVGHFTSTTTTLKRQQFSYTRPDEVALRHTNAINPRLTPWTYRNTSFSSLPLTGENPGAWALVRDNSAKGITAGSGSQQTTYDPTRTEAALTASTTFALRRYDLAGRALYDLDFSKLNPQTPTRDQTGQITFNPFGGFGLSGAAPQQWNEVKNKVPVEVAQDPSNPYRFAVLLVPRSVVYYEQLQRGLGLPQQRTESGQNTSTTGAMFGLKVKNAEADTAKSNEKLQGAEATGSSTTSGSGQSTQRGGSSGDTKVKALKIEVKKKSDSEDNGQLQLEKNDLANAPIKRSEESGQSVQLKADDFGTALSSSGSGGNSNPGSPTPWRPWLATEQIHKDLPKWSASILILYDAPYARNRTAIDRVDHLDPKAMTANYPPSWRTPKWNHHGLWDWKARDVLLQTTGFFNPRRHPEWFDGGQTVADNEKTGFDVDNSENTKQGFQKEADSDKSAPIALPFEAYFANIGNLTWFGQALLVFGGNGHVTKSAHTAPLSIGVFRVRYNATGTSATVTGWPYALLFSGMVNKQTDGLKDLPFNNNRWFEYVPRMAVAGAKFVGRELVLAGTITMGDTATVPRLLYDELESNLNLVAQGQGLLREDLQLFTPYGWANRPDLPIGAWSSSSSSSHNAPYYFHNNPDWQDRPIQNVVDAFIKPWEDKNGKDDAKYIYPYRYSGMWAWQVYNWSNKLTDQPLSADFVNENAYQPNSLFAAILNPELLAALPDKVKYGKENEFAANEYERFNQKLTVAPTQGTNWSHFSPTLSRFSTGFNLVGSVLDQVLDYVPWIGNGYRYGNNHRGVDDITAPQTSAGSSSGISTNTSGSRSFLPTFSNIGVGLKANVQATLGGSQTMITGGSPRRTLDQANLQLWTGAGWRNDKASSGQSDENHTKFTSATGMDQQGQSGTSAGNPDSLKQDNISKSGDSLTTQDGNAIDQQEATNYTNLPPNLTPTADWPNALSFTNKNNAQRAQLFLRGLLGSIPVLVNRSGSDSNKFQATDQKWSYTDLHSDQTKLNLPAYGEVNGLLNPALVETYFGNTRAGGSGSNTTSSPGIGFKIPEQNNDSKATLITPGLAWTPQDVGNLVVSGTTVSFQLGGWLVTFTDFVKPRAGYLGLQLTGLDASDATQRALIWAPRPWAAFRGSWVNRLGRVESVWDLKGVWADQAQSDSQGSTTTATRNALPEHPNALAFQVSVVEASAYKPNTSSGQTQSTNSSPYLHLVKPKKVTQSDKLDDDLKNLLDPNQVRTKLRQSFGTDHSTQPQPQSLKTTTPVFGTSSGNLSSVLSGGGAGGGSSGSGQSGVDLSPVEKVSGWLVGQLPSTSDGNTSSTNNLAPNTNTGNDVVGVGRLSESNAAKMNDDVDGIVRTPLAELLDGEGQTADTGPQSVKFKSPDQIDFNRLFTHPVTDLFDPVTMLVYDQYIPLFIDIPASVNPKMVRLKVLSFDTNEQSLGLRLEFFKPDQDTQPNNNVQVNPNNGDFLPLLTASSQGPQTLFSPFNQWPDYVLPLAITVPIVVIVLSVTLGLAIGIPMHKNKQALKAGFALSNQKVDVLTKAVGSVFKEIINRTGISQAPKRLKQTSAAKPGAPRPPVPPKPGAPKPPVQPPKKPA
Protein: Uncharacterized hemerythrin-like protein C869.06c (Q9URY9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Serine/threonine-protein kinase ppk24, mitochondrial
- TMEM14 protein homolog P14E8.05c
- Acireductone dioxygenase-requiring))
- Probable E3 ubiquitin-protein ligase mug30
- Cytochrome c oxidase polypeptide 5, mitochondrial
Sequence:
MLQYSKKKVSLNFFPVRLLSYKMTRISDAIFKDHRKLQSDYQNIKSANDYDTATRWQNQFVWELARHSVGEEIVVYPKFEKYLGEEGKEMAEKDRHEHQLVKEMLYKFQSMKANQSNFIPALDELMESLQKHIDEEEQHDIPFLEKHLSEEESLHMASSFERTKKFVPTHSHPSAPNKPPFETVAGLFAAPIDKLRDMMEKWP
Protein: AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (A2CG63)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity). Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4A. Involved in spermatogenesis, together with ARID4A, where it functions as a transcriptional coactivator for AR (androgen receptor) and enhances expression of genes required for sperm maturation. Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier. Plays a role in myeloid homeostasis where it regulates the histone methylation state of bone marrow cells and expression of various genes involved in hematopoiesis. May function as a leukemia suppressor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355}.
Interaction partners:
- Sin3 histone deacetylase corepressor complex component SDS3
- Histone deacetylase complex subunit SAP30
- Paired amphipathic helix protein Sin3a
- Histone-binding protein RBBP7
- Histone deacetylase 1
- Histone-binding protein RBBP4
- Histone deacetylase 2
- PHD finger protein 12
- Paired amphipathic helix protein Sin3b
- Histone deacetylase complex subunit SAP18
Sequence:
MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRHDSSTVEVQDDHIKGPLKVGAIVEVKNLDGAYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAESETLDQLPLTNPEHFGTPVIGKKTNRGRRSNHIPEEESSSSSSDDDEEERKQTDELLGKVVCVDYVSLEKKKAMWFPALVVCPDCSDEIAVKKDNILVRSFKDGKFTSVPRKDVHEITSDTVPKPDAVLKQAFDQALEFHKSRAIPANWKTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIDFQMALPEKVLNKPCKDCENKEVKVKEESETEIKEVNVEDSKNVMPKEETPAEDESERKENIKPSLGSKKSLLECIPAQSDEEKEAHITKLEENENLEDKDGGRARTEEAFSTEVDGEEEQARSGDETNKEEDEDDEEIEEEEEEDEEEDEDEDDDDNNEEEEFECYPPGMKVQVRYGRGKNQKMYEASIKDSDVEGGEALYLVHYCGWNVRYDEWIKADKIVRPADKNVPKIKHRKKIKNKLDKEKDRDEKYSPKNCKLRRLSKSPFQSNPSPEMVSKLDLADAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDERCTQDVDNIGKDESKVEHSTHSRNELISKEEQSSPSLLEENKVHTDLVIAKTVSKSPERLRKDMEAISEDTDFEEEDEITKKRKDVKKDTTDKALKPQTKRGKRRYCSADECLQTGSPGKKEDRTKSKEPLCTENSSNSSSDEDEEEKSKAKMTPTKKYNGLEEKRKSLRTTSFYSGFSEVAEKRIKLLNNSDERLQNNRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPHPAPDEGAVEESLQTVAEEESCSPIMELEKPLPASVDNKPIEEKPLEVSDRKTEFPSSGSNSVLNTPPTTPESPSSVTITEASQQQSSVTVSVPLPPNQEEVRSIKSETDSTIEVDSVVGELQDLQSEGNSSPAGFDASVSSSSSNQPEPDNPEKACTGQKRVKDTQGVGSSSKKQKRSHKATVVNNKKKGKGTNSSDSEELSAGESVTKTQTIKSVPTGMKTHNSKSPARVQSPGKGGRNGDKDPDLKEPSNRLPKVYKWSFQTSDLENMTSAERISILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERESAATSSSSSSPSSSSITAAVMLTLAEPSMSSASQNGMSVECR
Protein: Syndecan-4 (SYND4) (Ryudocan core protein) (O35988)
Organism: Mus musculus (Mouse)
Function: Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:10684261}. Note=Shedding of the ectodomain produces a soluble form. {ECO:0000269|PubMed:10684261}.
Interaction partners:
- Fibronectin
- Fibroblast growth factor 2
- Frizzled-7
- Thrombospondin-1
- Glypican-1
- Protein kinase C alpha type
- Paxillin
- Syndecan-1
- Thrombospondin-2
- Focal adhesion kinase 1
Sequence:
MAPACLLAPLLLLLLGGFPLVPGESIRETEVIDPQDLLEGRYFSGALPDDEDAGGSDDFELSGSGDLDDTEEPRPFPEVIEPLVPLDNHIPENAQPGIRVPSEPKELEENEVIPKRAPSDVGDDMSNKVSMSSTAQGSNIFERTEVLAALIVGGVVGILFAVFLILLLVYRMKKKDEGSYDLGKKPIYKKAPTNEFYA
Protein: Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B) (Q9Z223)
Organism: Mus musculus (Mouse)
Function: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Subcellular location: Cytoplasm, cytosol {ECO:0000255|HAMAP-Rule:MF_03052}.
Interaction partners:
- Molybdenum cofactor biosynthesis protein 1
- Adenylyltransferase and sulfurtransferase MOCS3
- Gephyrin
- SAGA-associated factor 29
- Sulfite oxidase, mitochondrial
Sequence:
MSSLEISNSCFSPETRSPSSRQSVEDNASEPSGKDVDDVQEKPKDIIQFTAEKLSVGEVSQLVVSPLCGAVSLFVGTTRNNFEGKKVISLEYEAYVPMAENEIRKICNDIRQKWPVRHIAVFHRLGLVPVSEASTVIAVSSAHRAASLEAVSYAIDSLKAKVPIWKKEIYEESTSSWKRNKECFWAAGD
Protein: Uncharacterized protein (Q57XT9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGKKKAERDKELSLTDMLGSAPPGSVPVQMQHGYGTANAQPRGGLAAGQAPPGQPPPGNYMLVGPGGMAPNVRHLSRGDPRLVSQQSPLRVAEGMDPRFCQPQMRPMTFRQDPSQVQPYNPGAPAPLSRSGILMHPGGMIPASQPPLHQNTHLYPYINNQRQTMPLQPQQGSAAHGPVAPPPSTTNTTEDKVEQESAPTESSASKKSSSKGVWGSVKGIFNVFKKGNKKGNAEQQQQQEEASAPAARNHNTMLQQPVADPEQRFRSNMLANATPGTSYVDPTKHSQSANATPFRQRVMQSGSGGTGGASPLRHTADMTQSRTLPAADTPCSSGKRRSNPVSSREIQSASHEKNQTNKRRQKDEGATASLSTTRALDDDSSSSDGLSAVGIGNQRNRNAQLKPIMSMPVPRPRNSDSDSDSEEVDAKAKKRATVEIPTTTEKVKKSDDRRGMTGRNQESSATQAPRRADNVEPVVKEAPAEAKSLETPAPFANHAAPVKGTAPMKTKHEETQPTKERIPSPAVTPKETPTPPQPVVKSGVGTGASTTGSGVTSFQKKETVSNDVSPTVNTSRAGAGRVIREIQKAKSPEPNRKHATDEREHGGTRGEDKRSTHPPRSHHGEIASERGEEVLREVKSTATNCREPNRSPSSSGKRATPVGANDRHSRGRTKEREKDTSSPVKKPSPRRKPSASKLVDCRVGQNKKRRPPQPDSSEDEREEEEDSDTDSDASVESYSGDKCDKGGTSPDKHGGHQPGHTHGYTDRGQRRTKAHGRSRGASHNDRSSSPSSIFRATDVYKLYFLLKQEMEESRRHKSSRLTCMRTPTRRALHGGRCTGYMHEGEERRSPWRHGRGCLDFLLPGAPPPSSMGYVSGGRRRSSRSMSTRDNYTSDRCRSSDSGRADRPRRASHTFDRSPSCCCCRSTCTHRCSHMARRRSHARGDGAADLHKNLSQRKASQMQERRLSAEPKDETRDSTRKGRGTRAAESGHSSAERRRTPAGMAAAPSDADGLKRDRNLKAPARVIDADGCISSTVPPDKKLSTNVSPCKPSVFETQRETCRSPSKEESQRSRRQCAEKLHVSDERISGRVPGSLSTSASWMDDAPTGTSRKTGPEGSDPSAATTERNVGGVAIPVVDLRWAFRPRSSSSAGSNTPVRNVRAPHASNFSAAHDRRRDRTGPTPSKRTDPARSMSVSSCGGTRRTADVTRLLLRELSSTSARRKSTWQPTRAFSCSGRQDTGDSPLLRRRSIRRTISQEGKRNEDTSSTSVVVLEEVKLDEQGRPYVLIREIPHGPKAVEAQRCLSERLSQPKFRRTRPGSVGV
Protein: U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70) (P17133)
Organism: Drosophila melanogaster (Fruit fly)
Function: Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA. Required during oogenesis for nurse cell chromatin dispersal.
Subcellular location: Nucleus speckle {ECO:0000250|UniProtKB:Q62376}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q62376}.
Interaction partners:
- U1 small nuclear ribonucleoprotein A
- Probable small nuclear ribonucleoprotein Sm D2
- U1 small nuclear ribonucleoprotein C
- Small nuclear ribonucleoprotein-associated protein B
- Small nuclear ribonucleoprotein Sm D3
- Putative RNA-binding protein Alsin2
- Probable small nuclear ribonucleoprotein G
- Probable small nuclear ribonucleoprotein Sm D1
- Probable U2 small nuclear ribonucleoprotein A'
- Nuclear cap-binding protein subunit 2
Sequence:
MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ
Protein: FI20035p1 (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Q9W2V2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Clathrin heavy chain
- Uncharacterized protein
- Uncharacterized protein, isoform A
- Uncharacterized protein, isoform B
- G protein-coupled receptor kinase 2
Sequence:
MSDKQQEKEPIPEEEQQQEQEREHEAPGSRHACCGSGPDPEAEPEVEMDVEVEEASGSAIGAAAAGESDAPAPANPNPGLERDRDRDSHGDRSTHRDEFGTQRVYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDEEVMGLRFCNEAIMSLHQIWPRLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPAKRYYGAPIGTSYDVRCFIADKTDEKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIAQSPPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGRSKSEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVDKPFLLHDGRVGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVADSDNVTPPVDRTVAAGASLNTTVTLRPQRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPHFVMQNAQLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKLTLSGMGGELSLKLPFVLVHVDETQRPGFASATLGELRMEMERLALHDAPVGKRNGRRQAQPTSAEIGDGPSTSAAAAAAAAAAKSASQSSGQSGGHLDMIESLDDEFNITVPVPRNGSHKRRLQRSETLARDLEEHEEHGPMPEEEDHIVQIHLEQVSPDRDEMQQEEQRVQEEQVSHAPGAETGAVPKSSNV
Protein: Acid trehalase (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase) (P78617)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Cytosolic neutral trehalase
- UDP-glucose 4-epimerase
- Alpha,alpha-trehalose-phosphate synthase
- Aldose 1-epimerase, putative
Sequence:
MRFKSVFTLLPLLAQLPSGGASLPNNHGRVENCVRNHDGIHKFRHSNNTYQSMFPGVTWDEDQWVLTTSSLDQGHYQSRGSVANGYIGISVSSVGPFFELDLPVAGDVINGWPLYSRRQSFATISGFFDIQAETNGSNFPWMNQYGGESVISGVPHWSGLILDLGDDDYLDSTVDNVTLSDFKSSYDFKAGVLSWSYTWTPAGDKGSYAITYRLFANKLNVNQAVVDMEITPSQDGHATIVNVLDGYSAVRTDFVESQEDDGAIYSAVRPWGIPDVSAYFYANITGSKHVDLSSRRLIHGKPYVSANESSIAQAADVNFVANEKVRITKFVGAASTDAFPDPQATAKRAVSEALDAGYQRSLRSHVQEWASIMHEDSVDRYVNPTTGKLPDDDNIINSAIIAVANTYYLLQNTVGKNAIRAAQDAPLNVNSFSVGGLVSDSYAGLVFWDADVWMQPGLVASHPEAAQAVTNYRTKLYPQAKKNIETTYTGSKNATYIDPSAAIYPWTSGRFGNCTGTGACWDYQYHLNGDIGLSLIYQWVVSGDTNTFREKHFPIYDSVAALYGSIVERNGSYWTLTNMTDPDEYANHIDAGGFTMPMISETLEYANQFRQQFGLEPNETWTEISENVLVLRENGVTLEYTTMNGTAAVKQADIVLVTYPLVYDNYTAETALTDLDYYANRQSADGPAMTWAIFSIAAGAVSPSGCSAYTYHQYSYAPYARAPFFQLSEQMLDNASINGGTHPAYPFLTGHGGANQVVLFGYLGLRLLPDDAIHIEPNLPPQIPYVKYRTFYWRGWPISAQSNYTHTVLQRSQSAPLDTADRRFANTSIPVFVGLADNATLHHLPPHGPLTVRNREIGTINTIEDNLIQCSPVSSTDAFEQGQFPISVVDGATSTRWQPSSSNASAVTVNLGSTTGRSVQTVASGFHFDWAAAPPVNASVIFHDTPLSDPVAALSSPGPHVRIVANLTNIEQSGPYDPEATDLNEIKIPVGNTTRIELAQEVPVGRYATLVISGNQALAQADGEDHVGATVAEWAILGPKSGSPRRRIQPVPLL
Protein: Mitochondrial import inner membrane translocase subunit TIM23 (Q9XVQ2)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Probable mitochondrial import inner membrane translocase subunit tim-17B.1
- Mitochondrial import inner membrane translocase subunit tim-16
- Mitochondrial import inner membrane translocase subunit TIM50
- COX5B-domain-containing protein
- Probable mitochondrial import inner membrane translocase subunit tin-44
- Mitochondrial import inner membrane translocase subunit TIM14
- Mitochondrial import inner membrane translocase subunit Tim21
- Heat shock protein hsp-6
- Mitochondrial import receptor subunit TOM40 homolog
- Mitochondrial import receptor subunit TOM22 homolog
Sequence:
MGWFGFGGNPTDTPSSSAEVSAAPIDLSAGMNFSVPGFDAPAPEPSVPDHSPFPAAPVLALDQLKSAGVGVSRQMTPYVQMDPSMFASQQPQYIMPEGGVAGKGKFEFALGHIGWAVGGAFGVGCARGALGELMNPETRKMVGKPWMTRMVNATMKHGSGFAQPSGAIVFMYSALEIGLRSVRAEDELNGFGAGALTGAIYRSPHGLKASGVGALVGLGIAAAWTLSSTDSRQRLSEMFSNH