wanglab/gogpt-training-data huggingface dataset:
Protein: Elongation factor 1-alpha (Q6P969)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Elongation factor 1-gamma
- GTP-binding nuclear protein Ran
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2a.
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- 3'-phosphoadenosine 5'-phosphosulfate synthase 1
- Small ribosomal subunit protein uS5
- Valine--tRNA ligase
- Large ribosomal subunit protein eL13
- Small ribosomal subunit protein uS13
- Ribosomal protein S3
Sequence:
MGKEKLHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPSYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEASPNMSWFKGWKITRKEGNAAGTTLLEALDAIQPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGLLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPQEAANFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMIPGKPMCVESFSEYPPLGRFAVRDMRQTVAVGVIKGVEKKTATSGKVTKSAQKAQKAK
Protein: Exported protein family 1 (Q8I0Q0)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MIIIVPFIFFNLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEEVAELLKDRLDLYIDNEDEWEKLMENEISMLLKSSFSSFILESIGWTYENVSNIFLEEKANSGINKKDIYLKEANERMIRNSIVLRQCKSRFISIITNYYPFKEQNNPFIKQAQYVSSSNYVLDDIINNIDYSIDNIHRAIDNLYYEHILNLLEEEKNEILEEILRNILKIILCDVETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKMILQKVN
Protein: U2 small nuclear ribonucleoprotein B, putative (Q57XJ8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Sm protein G
- Sm protein B
- G10 protein
- Sm protein F
- Cell division control protein, putative
- Splicing factor 3A, putative
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein E
- Uncharacterized protein
- Small nuclear ribonucleoprotein SmD1
Sequence:
MGEPKQTLYIRGLPDKPSAEEVRRLLYLYCTQFGPVIDVLYCKSKSMYGQAFVVFTDVATATNARRELHERQFYGRIIQAFYAKRQSFSADPGERRRRDLRQERVSGGKRRRDTQAG
Protein: Mediator complex subunit 12 (A0A096MKF8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 13
- Cyclin-C
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 27
- cyclin-dependent kinase
- Mediator of RNA polymerase II transcription subunit 24
- Mediator of RNA polymerase II transcription subunit 4
- Mediator of RNA polymerase II transcription subunit 23
Sequence:
MAAFGILSYEHRPLKRLRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLSDTGRRKSLMNQKDNFWLVTARSQSAINTWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKKKNTADPFTEWTQIITKYLWEQLQKMAEYYRPGPAGSGVCGSAIGPLPHDVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLDGVNSHSSHVISAQSTSSLPTTPAPQPPTSNTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGTPGPRPPSPFDDPADDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKDVKPPPKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFVFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVPGGTEELPEEEGGGGSSGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDSEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLLENIAKATIEVFQQSAETGSSSGSTASNMPSSSKAKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGERQSDSLEKVHQLLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPALLEPEKKAPEPPKTDKPGTAPPSTEERKKKSTKGKKRSQPATKSEDYGMGPGRSGPYGVTVPPDLLHHANPGSISHLSYRQSSMGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTTVMGLEPSSYKTSVYRQQQPTVPQGQRLRQQLQAKIQSQGMLGQSSVHQMTPSSSYGLQSSQGYTSYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMMGTMTPLSAQGVQAGVRSTSILPEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQPQQQQPHQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY
Protein: Putative UDP-glucuronate:xylan alpha-glucuronosyltransferase 5 (UDP-GlcA:xylan glucuronyltransferase 5) (EC 2.4.1.-) (Glycogenin-like protein 5) (Plant glycogenin-like starch initiation protein 5) (Protein GLUCURONIC ACID SUBSTITUTION OF XYLAN 5) (AtGUX5) (F4HZC3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the substitutions of the xylan backbone in stem glucuronoxylan.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Probable beta-1,4-xylosyltransferase IRX14H
- Probable beta-1,4-xylosyltransferase IRX9H
- Glucuronoxylan 4-O-methyltransferase 1
- Beta-1,4-xylosyltransferase IRX9
- Glycosyltransferase family 61 protein
- Glycosyltransferase
- Probable beta-1,4-xylosyltransferase IRX10
- Probable beta-1,4-xylosyltransferase IRX10L
- DNA polymerase delta small subunit
Sequence:
MGAKSKSSSTRFFMFYLILISLSFLGLLLNFKPLFLLNPMIASPSIVEIRYSLPEPVKRTPIWLRLIRNYLPDEKKIRVGLLNIAENERESYEASGTSILENVHVSLDPLPNNLTWTSLFPVWIDEDHTWHIPSCPEVPLPKMEGSEADVDVVVVKVPCDGFSEKRGLRDVFRLQVNLAAANLVVESGRRNVDRTVYVVFIGSCGPMHEIFRCDERVKRVGDYWVYRPDLTRLKQKLLMPPGSCQIAPLGQGEAWIQDKNRNLTSEKTTLSSFTAQRVAYVTLLHSSEVYVCGAIALAQSIRQSGSTKDMILLHDDSITNISLIGLSLAGWKLRRVERIRSPFSKKRSYNEWNYSKLRVWQVTDYDKLVFIDADFIIVKNIDYLFSYPQLSAAGNNKVLFNSGVMVLEPSACLFEDLMLKSFKIGSYNGGDQGFLNEYFVWWHRLSKRLNTMKYFGDESRHDKARNLPENLEGIHYLGLKPWRCYRDYDCNWDLKTRRVYASESVHARWWKVYDKMPKKLKGYCGLNLKMEKNVEKWRKMAKLNGFPENHWKIRIKDPRKKNRLSQ
Protein: Maternal effect embryo arrest 38 (Q9LXL8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- ADP-ribosylation factor GTPase-activating protein AGD10
- 110 kDa U5 small nuclear ribonucleoprotein component CLO
Sequence:
MAESSTRTRDGRGKSIVFEDSSTRGVGIVDRYREFVDQDGGILDQCEEWSRKIYRGVGIVVRYREFFDQNGGILDQYEEWSRRIYRVRGFIDQELKSSTGSENSTTRTRSGRGFIDYVLESSTGTENSSTRTAESSTRTKNGRSKSIVESGQSMGTPLLGSDLGSDRGILSDTDTRNDRPTVRPTDRPTDCPTDYRLFRQSAFLPFLSFTAVFRQKLMNRRGEWACLAQKLLSGREEWACHVSADMDSSRPRVGENGRVMHELTWILLGRLGGGIIILRTKYRDVPMGIDSIRLG
Protein: C3H1-type domain-containing protein (Q388W8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPSKKSMAKNRKTTVEVFDIEFRYMYEIPSHSVVHMPHVHPSNPYTMICTHYKPYDPNSCLAGSDCRFLHANVDYSTLKAHPIHVNYIWRHESECTYERCQSGDVLEVLLPNNKKPIERIASGLVLVTQAVIPQPSAEGRPLSHCAHYYFNGVCHRGASCNFVHAVAVDPEVDLSSNRILCRSHRRHHASGNKSGEKLSAGSPLDSSPGSFPDGTPLGFAMVVHKRVPSVGSSDVTSPTSGRDNGHLGLSGSGHQHDDCTTSDMNTISDGSAPRRPRFYRHNPYGL
Protein: Cilia- and flagella-associated protein 43 (A0A1L8GXY4)
Organism: Xenopus laevis (African clawed frog)
Function: Involved in the regulation of the beating frequency of motile cilia in multiciliated cells of the larval epidermis.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:E9Q7R9}.
Interaction partners:
Sequence:
MENSGCALEVRWVQGINKKKVTFINDHTVCYPCGNFIVFHDTNTGKWSFLQCTTGSTGAFAVNTYSEVVAFSDQKLHPTIYVYTFPGFVKRAELKDGAQLDYSLIAFSHAAPYLASYSSIPDHVLTIWNWQESIPLCSKSDSQTTYTTLTFNPMNWHQLCLSSERSLTVWNIEICDNQYQLKAMPVKLPSEDGTTDIEEENLNSHTSNSVSYYGPLMPTSAVAGLVGDEAEIFIPKEQRKHSVQPSFHCWNATSDLYVGCAGGQILSISAETQKVTILAQKDQSADHLSRTTLLEGNIKTMAFHKEGLYVAGNDGVLHLFTIKGSEVKLEDSWNAQEPIDSISFSPSYKTLSITTSKGSLYLYNQRNPEETYKLLNVYSRDLLAADFLTFGNKYCLGTDISGHVQLWSVEDGKSVSSLNLNIQATAMACCPSSNYAAVGSSTGHIYFIDAVKTEAPRIVQRTRLYCVPVQHMHFDPRGNFLLTGAADRHIFILDARPSYSFQVLGYIVVCGEILTLSSLSSADTQQTKVMALVCPVDERKEEKGGTQLEMFSLPLQMLSSPSEYIDERGMFKDTMIQKISYDVDQPLFSAVMGYNSSSVFGYSSNETILLKYVIHKDISGSPVTALVAEKVVRGSQLGPGVLCLSPHLKWMAVSGRDGIVYVKDLLNMETMAQLQCHSYHNGGINSLAFSLDGQSIVTTGTCDGALVCLQWKSSGRSSSRLGLAGEYGKDLALSLQAAMKEEDQALSRMPVWTADADSLGVERKGKEYSQLSVDVTEQDSFPNTSANDVTWIKRKLEEAEKKETEKYAAEKEVIKTGIKKLRKTIQAMMRENESLPDIEKLDQQEFNLDTEEQERLYLDSEKEVARVRQEIELENLSKQYLREVIKQECWDSMAVKGRSVTAFHTGYEVMNYPMKERTPKELEKFARVLNLMKIEAVDLKVRKEIVETQPKIGPDDEEEVEEELMKCQDSSSLVGSLSDHYGGDTSCLYSQLILHSREEKINQIILLQDIIQNIKNAFNKDFDTVCRQKEQEITRVMERNNRIQEIMVELNLQEKLLEPTFTDNEKPERALTVDDSEVKVERYLTPEQKAKAEHLAKVEEAKRLAAQEDNAKQRALDDMMGGVLEVKKEDILRMEVPQPVFLARTEAEWTEEEKKQFKEYEKKCKDLSEEKEKYSKEELKINNLLFSLLIEEEINTRVAHLAYILDKKRKQKNQTAEIVKSFKSQVMAFRESYDNLVAEDKLLDRGFKKEFSDITSYQVDQLYKLYKRRPRVQRLRTQADSTAPFGERPGSAKAYKDSIALLMHAMDELDTPENVPEGVELPVWQRFCLARRSKIEYEQQVKIKALVLAEMQAFLDKRIEEDEKMRQDIENFMQELNVLRNEKMKFQLDLTVQFLLKQGQVELENTDLIPSFEDAILLHRSVIEDLNSTIKGLGEQKIASMVESKDFRKGIFQLEWEHRKIRMEMEDLEKKSRDISLLHVSKEFQVFLNEQNYDKRMSDQIQVLEETINAQEKQHGKNVKTYKKILKDLETHINKKIIANLELDKDLQELLVSFSERKHIYDVVGVEQSTEKAAKERYMEIIQRRKLVDLAKIQAQEIHELRSEVDRLRMKTFPALVQMEY
Protein: Developmentally-regulated G-protein 3 (AtDRG3) (Developmentally-regulated G-protein 1) (AtDRG1) (Q9SVA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds GDP and GTP, and has low GTPase activity in vitro.
Interaction partners:
- Zinc finger CCCH domain-containing protein 21
- UPF0235 protein At5g63440
- Probable cysteine protease RD21C
- Cysteine proteinase RD21A
- Probable cysteine protease RD21B
- At1g09850
- Ubiquitin-conjugating enzyme family protein
- DNA polymerase epsilon subunit B
- Mitochondrial succinate-fumarate transporter 1
- Large ribosomal subunit protein uL23z
Sequence:
MSTIMQKIKEIEDEMAKTQKNKATSHHLGLLKAKLAKLRRDLLAPPTKGGGGGAGEGFDVTKSGDSRVGLVGFPSVGKSTLLNKLTGTFSEVASYEFTTLTCIPGVITYRGAKIQLLDLPGIIEGAKDGKGRGRQVISTARTCNCILIVLDAIKPITHKRLIEKELEGFGIRLNKEPPNLTFRKKDKGGINLTSTVAVTHLDLDTVKAICGEYRMHNADITLRYDATADDLIDVIEGSRIYMPCIYAVNKIDSITLEELEILDKLPHYCPVSAHLEWNLDGLLDKIWEYLDLTRIYTKPKAMNPDYDDPVILSSKKRTVEDFCIRIHKDMLKQFKYALVWGSSAKHKPQRVGKEHELEDEDVVQIVKKI
Protein: Tyrosyl/methionyl-tRNA synthetase, putative (EC 6.1.1.-) (Q57UK5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- arginine--tRNA ligase
- aspartate--tRNA ligase
- Lysine--tRNA ligase
- isoleucine--tRNA ligase
- glutamine--tRNA ligase
- proline--tRNA ligase
- Lysine--tRNA ligase
- leucine--tRNA ligase
- aspartate--tRNA ligase
- glutamate--tRNA ligase
Sequence:
MEGPFLSRSIQYVERWLAEIVATKGTRAAATGSSEKAVAQKRGKATATAAAETGATSMSKCRFVVGRVNSVRPHPESQKLYIEEIDLGEEGGKCRTILSGLQEYVKQEDFLNRLVLVIANLEPRKIGGIPSEGMVLCASCNDEGSRSVVLLDVPEGTPVGERILFEGHEGPYEPVLKKKLAKHFEEVAAELRTNDKGEVVWRDMPFRTSCGIITASIPNGSVS
Protein: Dec2 (Basic helix-loop-helix domain containing, class B, 3 like) (Basic helix-loop-helix family, member e41) (Class E basic helix-loop-helix protein 41) (Novel protein similar to vertebrate basic helix-loop-helix domain containing, class B, 3 (BHLHB3)) (Q2PGD2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Period circadian protein homolog 2
- Nuclear receptor subfamily 1 group D member 1
- Aryl hydrocarbon receptor nuclear translocator-like 1a
- Period circadian clock 3.
- Period homolog 1b
- Period circadian clock 1a.
- Nuclear receptor subfamily 1, group D, member 4a.
- BHLH-PAS transcription factor
- Nuclear receptor subfamily 1 group D member 2a
- Cryptochrome 3
Sequence:
MEERISRMQNRQFLDHADFLGVEYSSLYMCKSKRGMKREEGKDAYKLPHRLIEKKRRDRINECIGQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLNALTAVTEQQHQKIIALQNGERSLKSSLQADLDAFHSGFQACAKEVLQYLNKVENWTAREQRCTRLINHLHKVSAQFQPGTGILQQPVAGDDAPERDTQRDPQANCVPVIQRTQNLELNENDTDTDSGYGGEAEKGDGKSEKGCDTAKGVKIKQEFGDERVTKKAKMNWSANGGSDSTSTRPDVALMNSLMGMTGVGGQQTPFCMPFYFINPSAAASYMPLFDKSHLEKLVYPAAAAAALTTPFPWLYPGIPTHASAAAAAAIAFPNASTDKTSGFDAASSKDDEPESPDDDLSNEADLASPASEDHGSEIDTSHQPQRNDNDGT
Protein: F-box/LRR-repeat protein 15 (Q9SMY8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Terminal EAR1-like 1
- Cytochrome P450 78A5
- Protein MEI2-like 2
- Aminopeptidase M1
- Putative calcium-transporting ATPase 11, plasma membrane-type
Sequence:
MRIWCFSCFTDEDEDEEDDNGGRVKKQSLATAMDNSNGDGDFVNFGENERAPRVPRWRLRLCAEESEAAWAELDRFWTSEIPLNQLVQGESSSNVVAEAEDCTMEEADHDSYHKRAKVYSGLAECRSVSGVSSDAGNSVSSVERTVSFGIASSSRTDTDMFCQNFILNYNRKDGKKDDGDDNGSSDTEDFEVHIDLTDDLLHMVFSFLNHVDLCRSAMVCRQWRVASAHEDFWRVLNFENIRISMEQFENMCSRYPNATEVNVYGAPAVNALAMKAATTLRNLEVLTIGKGHISESFFQALGECNMLRSVTVSDAILGNGAQEIHLSHDRLRELKITKCRVMRLSIRCPQLRSLSLKRSNMSQAMLNCPLLQLLDIASCHKLLDAAIRSAAISCPQLESLDVSNCSCVSDETLREIAQACANLHILNASYCPNISLESVHLPMLTVLKLHSCEGITSASMTWIANSPALEVLELDNCNLLTTVSLHLSRLQSISLVHCRKFTDLNLQSIMLSSITVSNCPALRRITITSNALRRLALQKQENLTTLVLQCHSLQEVDLSDCESLSNSVCKIFSDDGGCPMLKSLILDNCESLTAVRFCNSSLASLSLVGCRAVTSLELKCPRIEQICLDGCDHLETAFFQPVALRSLNLGICPKLSVLNIEAPYMVSLELKGCGVLSEASIMCPLLTSLDASFCSQLRDDCLSATTASCPLIESLVLMSCPSIGSDGLSSLNGLPNLTVLDLSYTFLMNLEPVFKSCIQLKVLKLQACKYLTDSSLEPLYKEGALPALEELDLSYGTLCQTAIDDLLACCTHLTHLSLNGCVNMHDLDWGSTSVHLFDYFGVYSSSDNTQEPAETANRLLQNLNCVGCPNIRKVLIPPAARFYHLSTLNLSLSVNLKEVDLTCSNLVLLNLSNCCSLEVLKLGCPRLASLFLQSCNMDEAGVEAAISGCSSLETLDLRFCPKISSVSMSKFRTVCPSLKRVFSSPNLLQD
Protein: Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) (C9JIG9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRGEASNGLKTK
Protein: Cell wall protein ecm33 (O13960)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the negative feedback regulation of pmk1 cell integrity signaling and is linked to cellular calcium signaling.
Subcellular location: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Secreted, cell wall {ECO:0000269|PubMed:17230583, ECO:0000269|PubMed:20032302}.
Interaction partners:
- 1,3-beta-glucanosyltransferase gas1
- 1,3-beta-glucanosyltransferase gas5
- Uncharacterized GPI-anchored protein SPAC212.12
- Uncharacterized serine-rich protein C1E8.05
Sequence:
MLFKSFALTLLFAAARVQAASNCSSGPYNISAQGTLDELNSCTVLNGDLYISDAGNSGITTLTVNGIESVQGDVVVSDGQYLTSLSFPSLKNVSGAFNVNNMIRMNNLATPELTSVGSLNLAVLPNLQELQFNAGLSDSDSVVIDDTQLQAIDGISLDSVTTFQVTNNRYIQEITMEGLESAQNIQISANSKGVSVNFSKLSNVTTATFDGISNVFIGNLKSAAGNLYFSNTTLDNISVPYLTEIGQSFAVLYSPELTSLNFPNLTTVGGGFVINDTGLTSIDGFPVISEIGGGLVLLGNFSSIDMPDLSDVKGALTVETKATNFTCPWSNDDSVIKGDDFTCQGSVATISATSSYDLSSTVSATSGSATSATGSATTTSYSSDSSASSSSSSSHESSAASNGFTAGALVLGSLLVAALAM
Protein: GDP-mannose 4,6 dehydratase 2 (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD) (O45583)
Organism: Caenorhabditis elegans
Function: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
Interaction partners:
- GDP-L-fucose synthase
- Mannose-1-phosphate guanylyltransferase catalytic subunit beta
- Nucleotidyl transferase domain-containing protein
- GDP-mannose 4,6 dehydratase 1
- Dolichol-phosphate mannosyltransferase subunit 1
- Chitobiosyldiphosphodolichol beta-mannosyltransferase
- Putative polypeptide N-acetylgalactosaminyltransferase 11
- NAD
- GDP-fucose transporter
- L-fucokinase domain-containing protein
Sequence:
MEARNAEGLESCIEKIQEVKLSSFAELKAFRERKVALITGITGQDGSYLAELLLSKGYKVHGIIRRSSSFNTARIEHLYGNPVTHNGSASFSLHYGDMTDSSCLIKLISTIEPTEIYHLAAQSHVKVSFDLPEYTAEVDAVGTLRLLDAIHACRLTEKVRFYQASTSELYGKVQEIPQSELTPFYPRSPYAVAKMYGYWIVVNYREAYKMFACNGILFNHESPRRGETFVTRKITRSVAKISLRQQEHIELGNLSALRDWGHAKEYVEAMWRILQQDTPDDFVIATGKQFSVREFCNLAFAEIGEQLVWEGEGVDEVGKNQDGVVRVKVSPKYYRPTEVETLLGNPAKARKTLGWEPKITVPELVKEMVASDIALMEADPMA
Protein: Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK) (Q62406)
Organism: Mus musculus (Mouse)
Function: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state. When sumoylated, translocates to the nucleus and phosphorylates STAT3 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Lipid droplet {ECO:0000269|PubMed:21435586}. Note=Translocates to the nucleus when sumoylated (By similarity). RSAD2/viperin recruits it to the lipid droplet. {ECO:0000250}.
Interaction partners:
- TNF receptor-associated factor 6
- Myeloid differentiation primary response protein MyD88
- Interleukin-1 receptor-associated kinase 4
- Toll-interacting protein
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- TNF receptor-associated factor 3
- E3 ubiquitin-protein ligase pellino homolog 1
- Interleukin-1 receptor-associated kinase 3
- Interleukin-1 receptor-associated kinase-like 2
- NF-kappa-B essential modulator
Sequence:
MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSEQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPVVPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTKSSPESPVSGLQRAHPSPFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAGPPWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKSQGPEESDEFQS
Protein: Myomesin 1 (F1N9Z6)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MMSLPFYQRHHDHYDRAYRHKALQSTVSQYQKESKSKSAVYAQGSAAYARGSAAYRHASAADFSLDSSAAYSHGSSAHNLESAAYSYGSTAYDHAAVQSKRSAAYSLESEALSKSSAAYSHGSESINKLAAAYRLGSETYGLGLKDSNLMIEDQSYKMSPKAKRAKQTLVSEDKENEAVDYSVPIFTGREVNISGITDTEEERIKESAAYVAKRNLFATGEGVSVSKVAKSVSEEEHHEKKSRKVAIRESAERVALKKTLEDTQAFHKKLNQDKLLHPPEFVIKPRSHTIWEKQNVKFHCTVAGWPAPRVTWYKNNVPIDVQAHPGKYTIENRYGLHSLEISTCDFDDIAQYRASAMNVKGEISAYASLVVKRYKGEIDASYLHAGTFSMPLSLGVTPHGFASRFEIKFVDKFEVTFGREGETMSLGCTVVISPDIKRFKPDIEWYRNGVLITPSKWVQMHWSGERASLTLTHANKEDEGLYTLRVVMGEYYEEYSGYVFVRDADAEIPGAPGAPLDVQCLDANKDYVIVSWKQPAVDGGNPILGYFIDRCEVGTTHWTQCNETPVKFARFPVTGLIEGRSYIFRVRAVNKAGVSLPSRVSEPVAALDPADRARLRSHPSAPWTGQIIVTEEEPAEGVVPGPPTDLQVIEATKNYVVLSWKPPGQRGHEGIMYFVEKCIAGTEDWQRVNTEIPVKSPRFAVFDLSEGKSYCFRVRCCNSAGIGEPSEATEATVVDDKLDIPKPPGRIMPTRNTDTSVVVTWTESPDAKELVGYYIESSVVGSGHWEPCNNNPVKGTRFICHGLVNGEKYIFRVRAVNAAGLSEFSQDSEPIEVQAAIAAPSPPYDITVLESVRDSMVLGWKQPKATGGTEITGYYVNYREVIGGVPGKWMEANIKAVSERAYRIENLKENMVYQFQVAAANLAGVGTPSLPSKPFKCEEWTIAVPGPPHDVTYTEVRKDSLVLLWKEPVYTGRSPIAGYYVDMKETEANEEHWRSVNEKPLQKKFLKIAGLTEGVSYVFRVRATNQAGVGRPSDTTDPVVAETRPGTKEVVVNVDDDGVISLNFECDQMSPNSKFVWSKNYEPIEDDSRLDIDSKGGKSKAVFKDLGEDDLGIYSCVVTDTDGVSSGYTIDEEEMKRLLALSHEHKFPTIPLASELAVEILEKGEVRFWLQAEKLSGNAKANFVFNDKEIFNGEKYKMKVDQHTGLVEMIMDKLEDKDEGTYTFQLQDGKATNQSSLVLIGDVFKKLRDEAEFQRKEWHRKQGPHFVEQLGWEVTDECNVMLKCKVANIKKETHIVWYKDDREIMVDEEHDFKDGVCTLLISEFSKKDTGIYEVILKDDRGKDISELKLTDKAFADLMNEVCRRIALSATDLKIQSTAEGIRLYSFVTYYVEDLRVGWVHNDTQIRFTDRVKTGVTGEQIWLQINEPTPQDKGKYTMELFDGKTGHKKTVDLSGQAFDEAFAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLSCTVWGDPTPEVSWLKNEKSFVSDANCILRFESGKNVSFTISAVSTLDSGKYSLVVKNKYGTETSDVTVSVFIPEEEQEKNNEDKKTKA
Protein: Poly-cysteine and histidine-tailed protein (Ts-PCHTP) (D4N4Z9)
Organism: Trichinella spiralis (Trichina worm)
Function: Binds iron and zinc. May bind nickel.
Subcellular location: Secreted {ECO:0000269|PubMed:20967224}.
Interaction partners:
Sequence:
MAFSTIVVLFVAAVGFGNKISSADTCPEFGEWKPWTECLWYPMQNIYDKMTASCGLPGHRNLTNILPLPPGFTIPPPCGHCSFKTRCRTRPKKEGCYPFDGEREICHEHGDICTIAKLPGIGCGWTVLQEVVKQCLSRPDIPEYMRAGYKKLFHMLPKGHCIEKDNQCKCCCGDYEPNEDGTECVKQQDHQCAPFNEPGDWSECLWFPLADMFKKVQSHCGVEGKPEGLSPSSLAPAGFQIPEKCGFCSFRLKCQSREKKEGCFPLKVDKKSCGAEDCPTCGDVCTLDKQNNSCAFTKAMGMKFWNSFAHKAKESNLAHWRRDGYADLFKFLPYGHCKEVGDKCKCCCHPYEPNEDGTACVVKQYCKSLEEVGGKKQQKDQPESEKKAENMPETTGNASHHQHRHHHGDSSSESHEQHHHHHHH
Protein: tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6) (Q9UJA5)
Organism: Homo sapiens (Human)
Function: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P41814}.
Interaction partners:
- tRNA
- tRNA
- tRNA methyltransferase 10 homolog C
- tRNA
- pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3
- tRNA
- tRNA
- Ribosome biogenesis protein WDR12
- Probable ATP-dependent RNA helicase DDX56
- ATP-dependent RNA helicase DDX18
Sequence:
MEGSGEQPGPQPQHPGDHRIRDGDFVVLKREDVFKAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFEVTSGGSLQPKKKREEPTAETKEAGTDNRNIVDDGKSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITVVKPSTRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMGGFGSIIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSAKMLSSEPKDSALVEESNGTLEEKQASEQENEDSMAEAPESNHPEDQETMETISQDPEHKGPKERGSKKDYIQEKQRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVAMDNLKADTSLKSNASTLESHETEEPAAKKRKCPESDS
Protein: Probable transcriptional regulatory protein (Probably GntR-family) (P95098)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- HTH-type transcriptional regulator EthR
- Putative antitoxin HigA3
- Possible acyl-CoA dehydrogenase FadE16
- site-specific DNA-methyltransferase
- HTH-type transcriptional regulator Rv0792c
- Putative mycofactocin biosynthesis transcriptional regulator MftR
- Possible transcriptional regulatory protein
- Transcriptional regulatory protein
- Possible transcriptional regulatory protein
- HTH-type transcriptional regulator LysG
Sequence:
MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPATRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQSAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAASWWL