wanglab/gogpt-training-data huggingface dataset:
Protein: Head-specific guanylate cyclase (EC 4.6.1.2) (Guanylyl cyclase alpha 1 subunit) (Dgcalpha1) (Gycalpha99B) (Q07093)
Organism: Drosophila melanogaster (Fruit fly)
Function: May have a role in phototransduction. Catalyzes the conversion of GTP to cGMP, a common second messenger that is utilized in a wide variety of cells and signal transduction pathways. A second subunit is required for enzyme activity.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Guanylate cyclase soluble subunit beta-1
- Soluble guanylate cyclase 89Db
- Soluble guanylate cyclase 89Da
- Soluble guanylate cyclase 88E
- Inosine triphosphate pyrophosphatase
- Bis
- Uncharacterized protein, isoform B
- GTP cyclohydrolase 1
- Molybdenum cofactor biosynthesis protein 1
- cGMP-specific 3',5'-cyclic phosphodiesterase
Sequence:
MACPFFRRADSLTRQPSVIAEPGGHWALEDEELSDDALTLTHLQMAIQLLTAPSNEDLNTAVTSLVAKYRQNWPNIHKLKLDPQTFKSCANYDYLADIQELLLKMDEASASEILVLLGEELITCCCTGIIERAFRCLGTDLQEFLGSLDGVYDVLKLQEEDVTDTGFVCAGEGELIFTSERPVIAWLLLGSLKALTRMLYKVDVNIKIEPVEGDARRYRYLFSLVKDNSQTMLMGRPTSVSKTIPETVQRSNSSNASDLQMNSSSFCKMFPWHFIMNEQLELVQLGRGFSKLYKPYMADFGCQATTYFDFKRPKGLTMKFRDIVRRTYTPFLIGLNNPPGAVDFPAIGLEIKGQMVHCPESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVILVGEQARAQDGLRRRMDKIKNSIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSSIDAKTYPDVTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAHKVAWMALKMIDACSKHITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALKINVSPTTKDWLTKHEGFEFELQPRDPSFLPKEFPNPGGTETCYFLESFRNPALDSELPLVEHINVSMKTISEGGDA
Protein: Coiled-coil domain-containing protein 172 (TEKT2-binding protein 1) (Q6AXT4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q810N9}. Cell projection, cilium {ECO:0000269|PubMed:24394471}. Note=In caput spermatozoa, localized in the middle piece, but predominantly concentrated at the mitochondrial sheath of the flagella and to a lesser extent with outer dense fibers (ODF). Colocalized with TEKT2 at the perinuclear region (By similarity). {ECO:0000250|UniProtKB:Q810N9, ECO:0000269|PubMed:24394471}.
Interaction partners:
- Tektin-2
- Tektin 5.
Sequence:
MSLESLFQHIIFTEHQAEESRRVMREVRSEIARCRGKIKKATEDLNEEKIKLESKVQQFSEKTFLLELLKTRENALERQCSAIVSERDRLLQACEAIKKKTTEQEERFIKEITDFNDNYEITKKRDALMEEDIKLEMADLENQAEALRGEMKSMEYNSGQLQELQKLKSELLQELFTLQKKLKVLKDEETEAICITKHLEAEKIKIREKPQHDPECVRRLKRELDLYKEEDMESVCRALQIEVDLLESTLVPKDPQDNNSLSR
Protein: Midnolin (Midbrain nucleolar protein) (D4AE48)
Organism: Rattus norvegicus (Rat)
Function: Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4 (By similarity). Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion.
Subcellular location: Nucleus {ECO:0000269|PubMed:24187134}. Cytoplasm, cytosol {ECO:0000269|PubMed:24187134}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q3TPJ7}. Note=Detected in the nucleus and nucleolus with no expression in the cytoplasm (By similarity). However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus (PubMed:24187134). {ECO:0000250|UniProtKB:Q3TPJ7, ECO:0000269|PubMed:24187134}.
Interaction partners:
Sequence:
MEPQPGGARSCRRGAPGGACELSTTAESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQPPATPGPGRAAGGGFRKYRLILFKRPWHRQGPQSPERGGERPQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAAARGDSSIATPVSSPCRPVSSAARVPPVSSSPSSPVSPSPVTAGTFQSHAASTTCPEQTDCSPPASSNTTSTPGSSPTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPASLTQLRCHAQCSPASPAPDLTPKTTSCEKLATPSLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGRSDSSSSGGGGSPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA
Protein: Uncharacterized protein (G8BAP4)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Secreted, cell wall {ECO:0000256|ARBA:ARBA00004191}.
Interaction partners:
Sequence:
MKFSTVVATSLAFLSSAVVSKDVACLVDGQSVAVVDLDTGVCPFTIPSGLPAPVFTYTADDDYDVLFYYSLVESTKYFTDIVNAGTVISIPARLLYGTSGAPLYQVQAQEEPASNSTGAIRKRLMKGNALTPTPFNKRDAQSLADSLESKDGTFIANSAFEVVDVADVSSSSSAAGGETGVETIRSTTVLTETVDCSTTTGTTTLPNGETSTFTSSSPILSTVTADVTSVITITSCHEDLCHKTTVEATLSATTKTVSGIETIYTTYCPLSSVETPESTKVITTTDHEGKPTTVTAVPVLTTETVGGTVTEYVTYCPVSTSAGGAPPATSKPVKTTTYTSEGTVVTSTIYGTTEGTAGPSSVPVKTTTYTSEGTVVTSTIYGTTEGTAGPSSVPVKTTTYTSEGSVVTSTVYGTTEGSVAPSSVPVGTTTYTSEGTAVTSTVYGTVAGEGEGETTTAAGQPTTGAEGENTGVAETQTTVAGQSTTAAEGETSTAAVSTYEGVAASNGATYLALALVPLVYFI
Protein: Transmembrane protein 192 (Q9CXT7)
Organism: Mus musculus (Mouse)
Subcellular location: Lysosome membrane {ECO:0000250|UniProtKB:Q8IY95}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8IY95}. Late endosome {ECO:0000250|UniProtKB:Q8IY95}.
Interaction partners:
Sequence:
MAAAGRLEDSSLDILQSMDDDPLLDTQPLPHHSLQAQFRPRFHPLPTVIIANLLLLIHVVFVVLAFLTGVPCLYPNPTEDKCPENYTSPLKVQTAIILGKLILWILHLLFERYVQYHHRKVRSRGYSQIYRSTRHLKTLALTIHSSGNTALLLLLCVQHSFPEPSKLYLELILAVLALELICSLSCLILYIVKIRRFNRAKPLPDVLEEEKIYAYPSNTASETGFRTVSSLEEIVEKQEDIIVYLKRHNALLSKRLLELATQPART
Protein: Cysteine/serine-rich nuclear protein 2 (CSRNP-2) (Protein FAM130A1) (TGF-beta-induced apoptosis protein 12) (TAIP-12) (Q8BGQ2)
Organism: Mus musculus (Mouse)
Function: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May play a role in apoptosis.
Subcellular location: Nucleus {ECO:0000269|PubMed:17726538}.
Interaction partners:
Sequence:
MDAFSGSGLKRKFDDVDVGSSVSNSDDEMSSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAEEEPLPGAQSSQTQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSMESLGVCILEEPLAVPQELCPGLAAPILIQAQLPPGSSVLCFTENSEHPAASPMSSPSYLNSGPLVYYQVEQRPVVGVKAESGSEEGPASFPKEKDLSVFSLPVTSLVACGPSASAALCKPEVGKTSSLNKLLPEDCGLKEPESEDLHPSWSPSSLPFRTDNEEGCGVQNSQQSEDRTSEDSALELPLAV
Protein: Leukotriene B4 receptor 1 (Leukotriene B4 receptor 2a) (A0A0A8JZN4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MALQSPSFYTSTLHPTNLSNNTSDRGSIMGNKGGAITGAAILSLVFLLGVPGNVFIMWSILARARRRSITTLLILNLAFADGFLMLLTPFFMVYLVQRSWVFSLALCKVLYYLCCANMYASIFMIMLMSLHRLVAIVWPKRVGAKTERKMLTRVLVGLWVLALGLSAPVLAFRNILSDSKKPEKFVCDCIHPETQYEVMQYSMETLLGFLLPYGVIIGSYTCILRRIRKTRFRRRIRSEKLILVIVVTFGLFWLPYHIINMVQVTAALLPKESAAKQRLQEIRANMRALTSTVAFVSSCINPVLYTFAGKSYIRREGLAFMARLFEGTALESTRKIRRSNQNSRERDKETDEGDSIKDKDSDSINTINANSVIKVAPQNNGK
Protein: Intraflagellar transport protein 56 (Abnormal dye filling protein 13) (Tetratricopeptide repeat protein 26 homolog) (TPR repeat protein 26 homolog) (A8JA42)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly.
Subcellular location: Cell projection, cilium, flagellum {ECO:0000269|PubMed:24596149}.
Interaction partners:
Sequence:
MFYSKSRPQHAARTNVAQAAANEKPKVPELEEFLTKRDYLGAIALLSFRRHANRNDLKNLEWLAYCYFHYGEHDKALVIYKELLQHEDPDPMFFVYSAACLYYMGMYKEAEEQALQGPKCALQTRILFHSAQRQGNDDKLMAYHGQLTDSIEDQLTLASIHYQRSHFQEATDIYKRLLLEHRDYLRSTVVYVALCYCKLDYYDVSLEILGVYLSAFPDSAIAVNLKACNHFRMYNGKAAEAELKTLAELSGGQHLDHDLIRHNLVVFRGGENALQVLPPLSDIPPEARLNLVIHHLRHHEVGEAFGLIKDMEPSTPPEFILKAVVHAMLGQVKGDPEHLKKAQQYYQLVGASASECDTIPGRQCMASCFFLLKQFEDVLVFLSSIKTYFLNDDDFNWNLGIAKAATGKYKEAEETLLQIANDKYRNEYTYTSWLARCYIMNGKARLAWERYLQLETNDESYQLLLLIANDCYKMGAFYFACKAFDVLERLDPAPEYLEGKKGAACGAFQMIVAGKEPKDLLRDVISLLRGNNSADQCEPIVAVMRKWAKNNGVKL
Protein: Procyclin PARP A (Q26795)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MFRKSSELEGKCSSSPFVRRDSHTEASTKQAATLLLTFWFILFPYFSVGVFLLPPLGIGHSHMKALASAAKGGSVWYFLWRHLSSFPFRPPLFPWRKASGTVLPDDLCPVRSIMNNSYKSVCRYGGGYFPNRFGCFYYFVGRFKVGNSVHFQKNCDSYIWFYMEGGRAENVYVLAWMSRKINSSFRVFSVHYVIYGLAFRFV
Protein: E3 ubiquitin-protein ligase RMA (EC 2.3.2.27) (Protein RING membrane-anchor) (RING-type E3 ubiquitin transferase RMA) (Q8RXF2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}. Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU369090}; Single-pass type IV membrane protein {ECO:0000256|RuleBase:RU369090}.
Interaction partners:
Sequence:
MGEELADTMNLDLNLGPGPESDLQPAPNETVNLADWTNDPPERSSEAVTRIRTRHRTRFRQLNLPIPVLSETHTMAIELNQLMGNSVNRAAMQTGEGSERGNEDLKMCENGDGALGDGVLDKKADVEKSSGSDGNFFDCNICLDLSKEPVLTCCGHLYCWPCLYQWLQISDAKECPVCKGEVTSKTVTPIYGRGNHKREIEESLDTKVPMRPHARRIESLRNTIQRSPFTIPMEEMIRRIQNRFDRDSTPVPDFSNREASERVNDRANSILNRLMTSRGVRSEQNQASAAAAAIVAASEDIDLNPNIAPDLEGESNTRFHPLLIRRQLQSHRVARISTFTSALSSAERLVDAYFRTHPLGRNHQEQNHHAPVVVDDRDSFSSIAAVINSESQVDTAVEIDSMALSTSSSRRRNENGSRVSDVDSADSRPPRRRRFT
Protein: MIF4G domain-containing protein (Q57UX0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Probable eukaryotic initiation factor 4A
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- Eukaryotic translation initiation factor 4E, putative
- Serine/threonine protein phosphatase, putative
Sequence:
MHVYTIDQILELRSLYPEPPYPGFSLEEACRRKKQTQTKLVRGPNAWAARGSAKTTAEWVERLVYGSLNKLSAANFNEIVSQLQTNTIFSSDEMLKKTVSIIFNKALGEPENSNVYAGLCYKLAEYEVSLNVVQKQKEGKRLSKLRNAVVGIAQTEFQNRRNVPSSEGLSEEEVEQQRSSFMRRKVANMRFIGELFLHKVLSHSTMMDIINIIMQPEKGGYPASEDLEFLTVLFTIVGKSLDSIAELRPKLDAYFKVLEGLKDQKIYPPRICFKMLDLIELRRDRNWESRETVMPKTSAATQKEPPRASDRAVRSSTTPNSSNASSSGSKKGKGAGPCDSALGQRAAASTVGKDAREGLKSRAWRDVVKSEIVACDDHEMTVTESVAFEERVRSLFQEWLSGYRTGCLPNWQEEFRDCGARPIPDMDLPTAVAAQVVREACMTTRKDAQCEASRLMVIGLFLEDDQVFNGFAAALSSAIEEGILEDVPKFSERFANMLRFTSGDDVKTDVYYDAVRVLCTAYGMLRDPDEMSLSTLMEFWGKIPPPEKKEDAIFSLPVVQSLVTMTKLGRAQITGHIISSLHANGLVDDATLHEWLGTPGGEVDAEVKDAFRKATVGKGTLT
Protein: PHD finger protein 24 (Q9UPV7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGVLMSKRQTVEQVQKVSLAVSAFKDGLRDRPSIRRTGELPGSRRGTVEGSVQEVQEEKEAEAGTSVVQEESSAGRAAWERLRDGRGVEPEEFDRTSRFTPPAFIRPTRKLDDDKPPEICLEPREPVVNDEMCDVCEVWTAESLFPCRVCTRVFHDGCLRRMGYIQGDSAAEVTEMAHTETGWSCHYCDNINLLLTEEEMYSLTETFQRCKVIPDCSLTLEDFLRYRHQAAKRGDRDRALSEEQEEQAARQFAALDPEHRGHIEWPDFLSHESLLLLQQLRPQNSLLRLLTVKERERARAAFLARGSGSTVSEAECRRAQHSWFCKRFPEAPSCSVSISHVGPIADSSPASSSSKSQDKTLLPTEQESRFVDWPTFLQENVLYILAARPNSAAIHLKPPG
Protein: p-glycoprotein (Q5I1Z1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGKKDEIAVAKVKIEQNGDIGEDKDEEKKGEKEPKMPMIGAIALFRFADGWDRLMIVLGTIMAMVNGTVLPLMCIVFGDMTDSFIGDSIQTQNNFTNITFPVSNTTLGEEMTGHAIYYSIMGAVVLVAAYMQVAFWTLAAGRQVKRLMKLFFHCIMQQEIGWFDVNETGELNTRLTDDIYKINEGIGDKVGMLIQSFTTFVASFIIGFSKGWKLTLVILAVSPVLGFSAFIFSKVLTSFTSLEQSAYAKAGAVAEEVISSVRTVFAFGGQQKEITRYEKNLEDAKNMGIRKATSANIAMGFTFLMIYLSYALSFWYGSTLILSGEYTIGTVLTVFFTVLIGAFAMGQTSPNVQAFASARGAAHKVYNITDNKPHINSYSDHGYKPDVIKGNIEFNNIHFTYPSRPNVKVLNGMSLSVRSGQTIALVGSSGCGKSTTVQLLQRFYDPQDGSVYVDGHDVRSLNVRFLREMIGVVSQEPILFATTIAENIRYGRPDVTHQEIEQAAREANAHDFIMTLPDKFETLVGDRGTQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKVRQGRTTIVVAHRLSTIRNADVIAGFQKGEIVELGTHSQLMEKEGVYHTLVTMQTFKSPEEGEEAVEEQVLEEKSPSVTPFSETTLIRRKSTKGSSFVGSEKGDKDKTEVEEEVFAEQDQELVRQRSSFYSIMFALIGVVSFITMFLQGFCFGKAGEILTMKLRLMAFKAMMRQELGWYDSHKNSVGALTTRLATDAAQVQGATGVRLATLAQNVANLGTSLIISFVYGWQLTLLILCVVPVMAVAGGIQMKMLSGHAVKDKKELEQAGKTATEAIENIRTVASLTREQKFESLYQENLIVPYKNSQKKAHVYGITFSFSQAMIYFAYVGCFRFGAWLIEEGIMTFENVFLVISAVLYGAMAVGEANSFTPNYAKAKISASHLMFLINREPAIDNCSQGGETPDHFDGNVRFQGVRFNYPSRPDLAVLQGLELKVQKGQTLALVGSSGCGKSTTIQLLERFYDPLQGTVMLDNSDAKKLNIHWLRAQMGIVSQEPVLFDCSLAENIAYGDNTRKVTMKEIQSAAKAANIHSFIDDLPQKYDTQAGDKGTQLSGGQKQRIAIARAILRNPKVLLLDEATSALDTESER
Protein: Heat stress transcription factor B-3 (AtHsfB3) (AtHsf-05) (O22230)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Subcellular location: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
Interaction partners:
- Heat shock 70 kDa protein 4
Sequence:
MEDAGEHLRCNDNVNDEERLPLEFMIGNSTSTAELQPPPPFLVKTYKVVEDPTTDGVISWNEYGTGFVVWQPAEFARDLLPTLFKHCNFSSFVRQLNTYGFRKVTTIRWEFSNEMFRKGQRELMSNIRRRKSQHWSHNKSNHQVVPTTTMVNQEGHQRIGIDHHHEDQQSSATSSSFVYTALLDENKCLKNENELLSCELGKTKKKCKQLMELVERYRGEDEDATDESDDEEDEGLKLFGVKLE
Protein: TELO2 interacting protein 2 (E5RIH5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MELDSALEAPSQEDSNLSEELSHSAFGQAFSKILHCLARPEARRGNVKDAVLKDLGDLIEATEFDRLFEGTGARLRGMPETLGQVAKALEKYAAPSKEEEGGGDGHSEAAEKAAQVGLLFLKLLGKVETAKNSLVGPAWQTGLHHLAGPVYIFAITHSLEQPWTTPRSREVAREVLTSLLQVTECGSVAGFLHGENEDEKGRLSVILGLLKPDLYKESWKNNPAIKHVFSWTLQQVTRPWLSQHLERVLPASLVISDDYQTENKILGVHCLHHIVLNVAVLLCLLDLFPILEKTLHWKGDGARPTTHCDEVLRLILTHMEPEHRLLLRRTYARNLPAFVNRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLMQHTWPRVSCRLVVLLKALLKLICDVARDPNLTPESVKSALLQEATDCLILLDRCSQGRVKGLLAKIPQSCEDRKVVNYIRKVQQVSEGAPYNGT
Protein: Uncharacterized protein (Q38AH3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFSSVLLRGASEPGRRAITLPTLLDTVRRDPGMTAVYYANRYFGKERIMEVTRVLWGELKFHGQVTVDRIDGPEEPPRWYPVFSVPRKLHRIRRHCAEEEDLSVLQHTDLTSDSAAPAPGDNDASASFAAAVEDNIINLVHSIPGRNIQFYISELPTSMQPYGPMAFKRLRQAEVIIREQTPQGTFVWK
Protein: Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (G3V2J7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, perinuclear region {ECO:0000256|PIRNR:PIRNR037322}.
Interaction partners:
Sequence:
MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKDLPTSQFLPQSVLGMDPLT
Protein: Integration host factor subunit beta (IHF-beta) (P0A6Y1)
Organism: Escherichia coli (strain K12)
Function: One of the 2 subunits of integration host factor (IHF), a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
Subcellular location: Cytoplasm.
Interaction partners:
- Integration host factor subunit alpha
- Small ribosomal subunit protein bS1
- DNA-binding protein Fis
- CRISPR-associated endoribonuclease Cas2
- CRISPR-associated endonuclease Cas1
- DNA-binding protein HU-beta
- DNA-binding protein HU-alpha
Sequence:
MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
Protein: J domain-containing protein (E5QCE7)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}.
Interaction partners:
- Pleiotropic regulator 1
- Cell division cycle 5-like protein
- TPR_REGION domain-containing protein
- Heat shock protein hsp-1
- Pre-mRNA-processing factor 19
- Protein BUD31 homolog
- Septin and tuftelin-interacting protein 1 homolog
- Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15
- Ras-related protein Rab-3
- Uncharacterized protein T27F2.1
Sequence:
MNSDGLREAEEGRTSGGASPREESPAADHSHDPKKGLHLYNVLGIQKNATDDEIKKAYRKLALRYHPDKNLDGDPEKTEMFKEINYANAVLSNPNKRRVYDEMGETGLKLMEQFGEDEKILQWMLKPWFKWTFFAFGLLTGGFFCCCCGCMCCCQCCCNFCCGKYKPKHDDEFADETSDGDVIVDQPTASEPMPDTNNRQVPIVIAMPPPPSQKYGD
Protein: Intracellular hyphae protein 1 (Q9P403)
Organism: Colletotrichum lindemuthianum (Bean anthracnose fungus) (Glomerella lindemuthiana)
Function: May have roles in host-pathogen interaction, including establishment and maintenance of biotrophy, prevention of host recognition of the fungus and a barrier to host defense molecules.
Subcellular location: Secreted, cell wall {ECO:0000269|Ref.3}. Note=Cell wall and surrounding interfacial matrix.
Interaction partners:
Sequence:
MQTSFVALLAVAASLASALPHGGNSYEASLPEPTNLPEPTKLPEPVEGPYKPKPPILPEPIKDNYKPKTPILPEHVEGPYKPKLPEPTTGDPKNNTLPVPTCVDGKIKTHKVKSGESLTTIAEKYDTGICNIAKLNNLADPNFVDLNQDLQIPTDACEKDNTSCIKPDGTATCVKDGKKDGKDIYSVVSGDTLTSIAQALQITLQSLKDANPGVVPEHLNVGQKLNVPVC
Protein: Ribosome biogenesis protein NSA2 homolog (Hairy cell leukemia protein 1) (TGF-beta-inducible nuclear protein 1) (O95478)
Organism: Homo sapiens (Human)
Function: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
Interaction partners:
- Ribosome production factor 2 homolog
- GTP-binding protein 4
- Probable ribosome biogenesis protein RLP24
- mRNA turnover protein 4 homolog
- Nucleolar GTP-binding protein 2
- Pescadillo homolog
- Ribosome biogenesis protein WDR12
- pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3
- WD repeat-containing protein 74
- Probable rRNA-processing protein EBP2
Sequence:
MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV
Protein: Dual specificity protein phosphatase OPG106 (EC 3.1.3.-) (EC 3.1.3.48) (Dual specificity protein phosphatase H1L) (Late protein H1) (P07239)
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Function: Serine/tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated host STAT1 and blocking interferon (IFN)-stimulated innate immune responses. Dephosphorylates the OPG144 protein.
Subcellular location: Virion {ECO:0000269|PubMed:21362620}. Host cytoplasm {ECO:0000269|PubMed:21362620}. Note=Approximately 200 molecules of OPG106 are packaged within the virion and are essential for the viability of the virus.
Interaction partners:
Sequence:
MDKKSLYKYLLLRSTGDMHKAKSPTIMTRVTNNVYLGNYKNAMDAPSSEVKFKYVLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSKCDQRNEPVLVHCAAGVNRSGAMILAYLMSKNKESLPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYVIDKN
Protein: GH26608p (Q8SWT0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPHSPEAPLHDELRLYAPLRCGHPGGQLGLGQERERGAAPAYHGPGGLQVHHLPREIRSHPDLHQQHARRRQVPAESIHHPLGPEGSGFPETLLLHHRHQGGALARCTP
Protein: Viridiflorene synthase (EC 4.2.3.88) (Terpene synthase 32) (SlTPS32) (EC 4.2.3.-) (G5CV45)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Sesquiterpene synthase involved in the production of viridiflorene from (E,E)-farnesyl diphosphate. Can also use (Z,Z)-FPP to make several unidentified sesquiterpenes.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Uncharacterized protein.
Sequence:
MALLNNQDEIVRPVANFSPSLWGDRFHSFSLDNQVADKYAQQIETLKEQTRSLLSDAACGTTLAEKLNLIDIVERLGLAYHFEKQIEDMLDQIYKADPNFEAHDLNTLSLQFRILRQHGYNISQKIFSRFQDANGKFKESLSNDIKGLLNLYEASHVRTHGEDILEEALAFSTAHLESAAPHLKSPLSKQVTHALEQSLHKSIPRVETRYFISIYEEEEFKNDVLLRFAKLDYNLLQMLHKQELSEVSRWWKDLDFVTTLPYARDRAVECYFWTMGVYAEPQYSQARVMLAKTIAMISIVDDTFDAYGIVKELEVYTDAIQRWDISQMDRLPEYMKVSFKALLDLYEDYEKELSKDGRSDVVQYAKERMKEIVRNYFVEAKWFIEGYMPPVSEYLSNALATSTYYLLTTTSYLGVKSATKEDFEWLAKNPKILEANVTLCRVVDDIATYEVEKGRGQIATGIECYMRDYGVSTQVAMDKFQEMAEIAWKDVNEGILRPTPVSTEILTRILNLARIIDVTYKHNQDGYTHPEKVLKPHIIALLVDSIEI
Protein: P-loop containing nucleoside triphosphate hydrolases superfamily protein (Putative DNA2-NAM7 helicase family protein) (O64476)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transducin/WD40 repeat-like superfamily protein
- Transducin/WD40 repeat-like superfamily protein
- Transducin/WD40 repeat-like superfamily protein
- 5'-3' exoribonuclease 2
- DEAD-box ATP-dependent RNA helicase FANCM
- non-specific serine/threonine protein kinase
- tRNA-splicing endonuclease subunit Sen2-1
Sequence:
MDSDASAKENTQDLSDYKGMIETGGEGSVRDELQEPGLMVKQREVKGVEASYAVKCANTTVKRKMDQHKEAMLGKKRNRQTRFLNLEDVKQAGTVNTSTPRRQNFAQAVPTRSSAVNPPAEHGGESQSQSHQNLKSVDFPSTGGIHSESAEQKTESNGESYSGLLGKPRRLNRDEEPSAEGMGTSVSRQASWKQPANIRQPKSGHSSSRKVSYSQRSFKKPATSSTQYQDTSVERLIREVTNEKFWRHPEDTELRSVPERFESMEEYVRVFEPLLFEECRAQLYSTWVELAEANTYVKVRIKSIERRERGWYDVILNSLNGCKWAFKEGDVAVLSTPLPESDEDHEDAGRVAGTVRRHIPVDTRDPRGATLHFYVGNSGGTGSKIDDSHILRKLKPQDIWHLTVLGSLATTQREYVALHAFSRLNPQMQNAILNPSPEQFPSYEEQTPATPDCFTTSFVDHLHRSFNAPQLAAIHWAAMHTAAGTSSGVKKQEPWPFTLVQGPPGTGKTHTVWGMLNVIHLVQYQQYYTSLLKKLAPETYNQANECSSSDNILSGSIDEVLQNMDHNLFRTLPKLCAKPRMLVCAPSNAATDELLSRVLDRGFIDGEMRVYRPDVARVGVDSQSRAAQAVSVERRSDQLLAISRDEILRHMRNLRLQETQISQNIAGLKRELNAAAFATRSQGSVGVDPEVLISRDQKRDALLQHLAAVVEARDKVLVEISRLLIVEGKFRAGNNFNLEEARASLEASFANEAEIVFTTVSSSGRKLFSRLTHGFDMVVIDEAAQASEVGVLPPLALGAARCVLVGDPQQLPATVISKAAGTLLYSRSLFERFQLAGCPTLLLTVQYRMHPQIRDFPSRYFYQGRLKDSESISSAPDEIYYKDPVLRPYLFFNISHGRESHRGGSVSYENVDEARFCVGVYMHLQKTLKSLGAGKVSVGVITPYKLQLKCLKHEFGNALGQDELKEIYINTVDAFQGQERDVIIMSCVRASGHGVGFVSDIRRMNVALTRARRALWVMGNASALMKSEDWAALISDARGRNCFMEMDSLPLDFPIPKVSSYNPMAPNNGLITSKLYPSDAPIIGLHTKLR
Protein: Heavy metal tolerance protein (Q02592)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in metal tolerance. Probably involved in the transport of metal-bound phytochelatins. Compartmentalizes cadmium within vacuoles, thereby protecting cells from cadmium toxicity.
Subcellular location: Vacuole membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MVLRYNSPRLNILELVLLYVGFFSIGSLNLLQKRKATSDPYRRKNRFGKEPIGIISWWILGIALTYVVDISNLVIYALRVPNWWPCKTTVVCLILFLLFWIIVLISCADSKALPKNADSILKAYRLSVLYVWAIDIVFETIFIVYSPHPNETFQGIVLADHVARLVLCVFATAIYLTYRRKRHTHDPLDFEERQLTEESNVNENAISQNPSTVQLGVSASTSNFGTLKSTSKKPSDKSWAEYFRSFSTLLPYLWPTKDYRLQFQIFICIVLLFLGRAVNILAPRQLGVLTEKLTKHSEKIPWSDVILFVIYRFLQGNMGVIGSLRSFLWVPVSQYAYRAISTKALRHVLNLSYDFHLNKRAGEVLTALTKGSSLNTFAEQVVFQIGPVLLDLGVAMVYFFIKFDIYFTLIVLIMTLCYCYVTVKITSWRTEARRKMVNSWRESYAVQNDAIMNFETVKNFDADDFENERYGHAVDIYLKQERKVLFSLNFLNIVQGGIFTFSLAIACLLSAYRVTFGFNTVGDFVILLTYMIQLQQPLNFFGTLYRSLQNSIIDTERLLEIFEEKPTVVEKPNAPDLKVTQGKVIFSHVSFAYDPRKPVLSDINFVAQPGKVIALVGESGGGKSTIMRILLRFFDVNSGSITIDDQDIRNVTLSSLRSSIGVVPQDSTLFNDTILYNIKYAKPSATNEEIYAAAKAAQIHDRILQFPDGYNSRVGERGLKLSGGEKQRVAVARAILKDPSIILLDEATSALDTNTERQIQAALNRLASGRTAIVIAHRLSTITNADLILCISNGRIVETGTHEELIKRDGGAYKKMWFQQAMGKTSAETH
Protein: Persephin (PSP) (O60542)
Organism: Homo sapiens (Human)
Function: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.
Subcellular location: Secreted {ECO:0000269|PubMed:9491986}.
Interaction partners:
- GDNF family receptor alpha-4
- GDNF family receptor alpha-1
- GDNF family receptor alpha-3
- Proto-oncogene tyrosine-protein kinase receptor Ret
- GDNF family receptor alpha-2
- Glial cell line-derived neurotrophic factor
- Neurturin
- Artemin
- GDNF family receptor alpha-like
- High affinity nerve growth factor receptor
Sequence:
MAVGKFLLGSLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGRAHGGPCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG
Protein: IP13478p (Q4V566)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- BPTI/Kunitz inhibitor domain-containing protein
- BG642163, isoform A
- Lipase
- Lipase
- Seminal fluid protein
- GH23626p
- GH10507p
- MIP10846p1
Sequence:
MKSTVWLPLLTLIWRSASANPILGLFDPACQVVRGECPNKNISFWLYSNSTRENPILLDPLDLNPWNFQPPRPLKILIHGYTGDRDFAPNSYIRPVLLDHEDVYVISIDYGPLVRYPCYIQAVQNLPLVSRCLAQLINNLVDRAIVANDQIHLIGFSLGGQVAGQTANYVKRKMKRITGLDPAKPLFILGPDSRRLDKGDADFVDVIHTDVFGRGYLRAAGHVDFYPNFGAKQPGCMEENMQDPSSCNHERAPRFYAESINTTVGFWARQCSGWLLQLLTLCPTTGAQALLGYHVSDELRGSYFLQTASKSPYALGKMQDVDNRQTLAKFHLNFDHNEIDDDYEPQLLEAFLELEAVKVVVKMDESELDKRLNWIYREEDEPLSRNLIK