wanglab/gogpt-training-data huggingface dataset:
Protein: Chorismate synthase, chloroplastic (EC 4.2.3.5) (5-enolpyruvylshikimate-3-phosphate phospholyase) (Protein EMBRYO DEFECTIVE 1144) (P57720)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the last common step of the biosynthesis of aromatic amino acids, produced via the shikimic acid pathway.
Subcellular location: Plastid, chloroplast {ECO:0000250}.
Interaction partners:
- 3-phosphoshikimate 1-carboxyvinyltransferase, chloroplastic
- Chorismate mutase 2
- Chorismate mutase 3, chloroplastic
- Chorismate mutase 1, chloroplastic
- 3-phosphoshikimate 1-carboxyvinyltransferase
- anthranilate synthase
- Anthranilate synthase beta subunit 2, chloroplastic
- Anthranilate synthase alpha subunit 1, chloroplastic
- anthranilate synthase
- Anthranilate synthase beta subunit 1, chloroplastic
Sequence:
MASSSLTSKSILGSTKLGSSSLPSELRRLSSPAVQISLRTQTRKNFQIQATGSSYGTHFRVSTFGESHGGGVGCIIDGCPPRIPLTESDLQFDLDRRRPGQSRITTPRKETDTCRISSGVSEGMTTGTPIHVFVPNTDQRGLDYSEMSVAYRPSHADATYDMKYGVRSVQGGGRSSARETIGRVAPGALAKKILKQFAGTEILAYVSQVHHVVLPEELVDHENLTLEQIENNIVRCPNPEYAEKMIAAIDAVRTKGNSVGGVVTCIVRNAPRGLGTPVFDKLEAELAKACMSLPATKGFEFGSGFAGTFLTGLEHNDEFYTDENGRIRTRTNRSGGIQGGISNGEIINMRVAFKPTSTIGRKQNTVTRDKVETEMIARGRHDPCVVPRAVPMVEAMVALVLVDQLMAQYAQCHLFPINPELQEPLQIEQPQNATAL
Protein: Cholesterol ring-cleaving hydrolase IpdB subunit (EC 4.1.99.-) ((3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase beta subunit) (COCHEA-CoA hydrolase beta subunit) (P9WPV9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the final steps of cholesterol and steroid degradation. Opens the last steroid ring of cholesterol by catalyzing the hydrolysis of (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) to 6-methyl-3,7-dioxodecanedioyl-CoA (MeDODA-CoA).
Interaction partners:
- (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA hydrolase (HIEC-CoA hydrolase)
- Cholesterol ring-cleaving hydrolase IpdA subunit
- Probable short-chain type dehydrogenase/reductase
- 
- Steroid 3-ketoacyl-CoA thiolase FadA6
- Acyl-CoA dehydrogenase IpdE1
- Probable short-chain type dehydrogenase/reductase
- 
- Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit A
- Probable acyl-CoA dehydrogenase FadE31
Sequence:
MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDPKSLRDREIRS
Protein: Mitochondrial import receptor subunit TOM20 (Mitochondrial 20 kDa outer membrane protein) (Protein MAS20) (Translocase of outer membrane 20 kDa subunit) (P35180)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore.
Subcellular location: Mitochondrion outer membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial import receptor subunit TOM7
- Mitochondrial import receptor subunit TOM40
- Mitochondrial import receptor subunit TOM70
- Mitochondrial import receptor subunit TOM22
- Mitochondrial import receptor subunit TOM5
- Sorting assembly machinery 37 kDa subunit
- Mitochondrial import receptor subunit TOM6
- Sorting assembly machinery 50 kDa subunit
- Sorting assembly machinery 35 kDa subunit
- Non-selective voltage-gated ion channel 1
Sequence:
MSQSNPILRGLAITTAIAALSATGYAIYFDYQRRNSPQFRKVLRQRAKEQAKMEEQAKTHAKEVKLQKVTEFLSMELAKDPIPSDPSEREATFTTNVENGERLSMQQGKELEAASKFYKALTVYPQPADLLGIYQRSIPEAIYEYIILMIAILPPANVASFVKGVVGSKAESDAVAEANDIDD
Protein: Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B) (Q8K0G8)
Organism: Mus musculus (Mouse)
Function: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Protein enabled homolog
Sequence:
MTPPPPPPPPPGPDPAVDSATDPCPEPQSLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAALSPQCREASGLSADSLARAESLDKVLQQFSQLVSGDVALLGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGSNGQLFSKPEVVKQKYETGPCSKADVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPTDVLGFLGPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYAASPLLPTLTAPLLPIPFPLAGGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMMSVERALAAAQRCHKKMMKERYVEVVPCSTEEMSRVLMGGSLSRSGLSPPPCKLPCLSPPTYATFQATPALIPTETTALYPSSALLPAARVPAAATPLAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPTALASTPTTMLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLAPDDYTTLMPVGDPPRTVLQAPKEWVCL
Protein: Gamma-crystallin S (Beta-crystallin S) (Gamma-S-crystallin) (O35486)
Organism: Mus musculus (Mouse)
Function: Crystallins are the dominant structural components of the vertebrate eye lens.
Interaction partners:
- Alpha-crystallin A chain
- Lens fiber major intrinsic protein
- Alpha-crystallin B chain
- Phakinin
- Gap junction alpha-8 protein
- Filensin
- Gap junction alpha-3 protein
- Heat shock factor protein 4
- Beta-crystallin B2
Sequence:
MSKTGGKISFYEDRNFQGRRYDCDCDCADFRSYLSRCNSIRVEGGTWAVYERPNFSGHMYILPQGEYPEYQRWMGLNDRLGSCRAVHLSSGGQAKIQVFEKGDFNGQMYETTEDCPSIMEQFHLREIHSCKVVEGTWIFYELPNYRGRQYLLDKKEYRKPVDWGAASPAIQSFRRIVE
Protein: Arginine/agmatine antiporter (P60063)
Organism: Escherichia coli O157:H7
Function: Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach (Probable). Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons. Probably undergoes several conformational states in order to translocate the substrate across the membrane; keeps the substrate accessible to only 1 side of the membrane at a time by opening and closing 3 membrane-internal gates (Probable).
Subcellular location: Cell inner membrane {ECO:0000305|PubMed:19478139}; Multi-pass membrane protein {ECO:0000269|PubMed:19478139, ECO:0000269|PubMed:20090677}.
Interaction partners:
Sequence:
MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIYGWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNIAMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALIPIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILMTIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTTIAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD
Protein: methionine--tRNA ligase (EC 6.1.1.10) (Q38C91)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- isoleucine--tRNA ligase
- leucine--tRNA ligase
- Methionyl-trna formyltransferase
- serine--tRNA ligase
- 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
- arginine--tRNA ligase
- Tyrosyl/methionyl-tRNA synthetase, putative
- proline--tRNA ligase
- asparagine--tRNA ligase
- glutamate--tRNA ligase
Sequence:
MALKLLSEKANSQALKVLLCSYYVKRPVEVSLSGAYATPILHHPAFKQPIIAPNEMARVILFYSVEPTSNNGGAADSSNGDGTASPVAGLTNLTLEHETWLEWEATTFTRAVHPLYTQRRQTAESLAVFSYLDKKISENDDRCVYSPAVEGKGAADPTDAVSTFFIDCIVWCAVLPALCESGVLRDSEKQQLPHLVKWFNTFQKEQKTLIDNAFENLSVQEAADFLRCPRVYKVSAKVEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTAAVAGEFKKCFEQMDYSIDYFIRTTNEQHKAVVKELWTKLEQKGDIYLGRYEGWYSISDESFLTPQNITDGVDKDGNPCKVSLESGHVVTWVSEENYMFRLSAFRERLLEWYHANPGCIVPEFRRREVIRAVEKGLPDLSVSRKKETLHNWAIPVPGNPDHCVYVWLDALTNYLTGSRLRVDESGKEVSLADDFSELERFPADVHVIGKDILKFHAIYWPAFLLSAGLPLPKKIVAHGWWTKDRKKISKSLGNVFDPVEKAEEFGYDALKYFLLRESGFSDDGDYSDKNMIARLNGELADTLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAPWKLVKTDPERLRTVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHRKGIENFEFGAVPPGTRLGPAVEGEVLFSKRSTENTKST
Protein: Uncharacterized protein (Q57ZP8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 30S Ribosomal protein S17, putative
- Rhodanese domain-containing protein
- Uncharacterized protein
- Opioid growth factor receptor
- Treble clef zinc finger domain-containing protein
- Small ribosomal subunit protein mS41
- Uncharacterized protein
- Small ribosomal subunit protein uS5 C-terminal domain-containing protein
- Uncharacterized protein
- Ribosomal protein S23 mitochondrial conserved domain-containing protein
Sequence:
MFRRAIPLLSANIPRSVWDPAQHNPNWSDSYGHDITNRRAWPARKWTVGLEPCTPREWLQFSHRNLAYAYNGALRACHSLPSMLLLYKEMKQRGVKVDVDTMNVLLTRAARHEHIQVDDVFLLFDELVALGARPDLAAAETLHTVLSHSASMPEEWREARRLQLVELYNNLAMEEVERLAPHRADRLLKEQMKRFRGNLQQLGSGLRPTVYCRYLHTTHTAAVLLEEVHNFLWELVPNDHPAMEIPALQLRVPFVASVLRRPSVNPGVSLASVSRAEFGDTDVCAVFLAAAERMVDADFDDQRPVSERRLFLSLLTMISYSGVLYTSDLMAQLMEMVKYSNNDETRDSDAQRVLRYALRGSSAAQDSASRTLWHSVEKVADCRVVGRYIGARNPWNPIRVCFDEQGVFKAYPISTTTTTREVSPPEGSSAVTQEQRASCVEGRTLEALNMRWDDVRRLIECTGVLVTPPSERCPQQQKMEVFTGMAVYLRTVATGRRYEGGEDVLSDGAVATSSCEQRRRGTLFAEGYDFDVWVRLFSLVQEVRHDMEKFMADHTLQCVEPEFECWEALLVTLRCALDFCVVQMQGGGARGTEREVVERLFRDVVALREELIEESRTRFGGRMRVLWLQEA
Protein: Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Q8GUI9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Neutral ceramidase 3
- Neutral ceramidase 2
- Neutral ceramidase 1
- Ceramide kinase
- beta-galactosidase
- Sphingolipid delta
- Beta-galactosidase 2
- Beta-galactosidase 17
- AP-2 complex subunit sigma
- AP3-complex subunit beta-A
Sequence:
MFEEKIMDIGEDVKPLNSSDTKVDPAVPASLTWQRKIDSDVKAPREFNLSVKEIFQLAPVGIRLWFLCREEAAKGRLAFIDPFSKHSVTSSHGVPLGGIGAGSIGRSFKGEFQRWQLFPPKCEDEPVLANQFSAFVSRANGKKYSSVLCPRNPKLDKQDSESGIGSWDWNLKGDKSTYHALYPRSWTMYEGEPDPELRIVCRQVSPFIPHNYKESSFPVSVFTFTLHNLGNTTADVTLLFTWANSVGGDSEFSGGHYNSKITMNDGVQGVLLHHKTANGLPSLSYAISAQATDGVSVSACPFFIVSGKQDGITAKDMWQAVKENGSFDHLKASEASMQSDHGSSIGAAVAASVTVLPGESRIVTFSLAWDCPEVQFPSGKIYSRRYTKFYGNNGDAAAQIAHDAILGHSQWESWIEDWQRPILEDKRLPAWYPVTLFNELYYLNSGGTLWTDGSSPVHSLAGVREKKFSLDKSQLGLKNDIDVPHQNDTAVSVLEKMASTLEELHASTTSNSAFGTKLLEEGEENIGHFLYLEGIEYRMWNTYDVHFYASFALVMLFPKLELSIQRDFAAAVMLHDPTKVKTLSEGQWVQRKVLGAVPHDLGINDPWFEVNGYTLHNTDRWKDLNPKFVLQVYRDVVATGDKKFASAVWPSVYVAMAYMAQFDKDGDGMIENEGFPDQTYDTWSASGVSAYCGGLWVAALQAASALARVVGDKNSQDYFWSKFQKAKVVYEKKLWNGSYFNYDNSGSQYSSTIQADQLAGQWYARASGLLPIVDEDKARTALEKVYNYNVMKIKDGKRGAVNGMHPNGKVDTASMQSREIWSGVTYALSATMIQEGLVEMAFQTASGIYEAAWSETGLGYSFQTPESWNTVDEYRSLTYMRPLAIWAMQWALTKTSQKQEQLGLEPEQQEPELEPSSSMKHDIGFSRVSRLLSLPNEASAKSTLQTLFDYTCRRMMS
Protein: Pyruvate decarboxylase isozyme 1 (EC 4.1.1.-) (EC 4.1.1.43) (EC 4.1.1.72) (EC 4.1.1.74) (Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase) (2ODC) (P06169)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Major of three pyruvate decarboxylases (PDC1, PDC5, PDC6) implicated in the nonoxidative conversion of pyruvate to acetaldehyde and carbon dioxide during alcoholic fermentation. Most of the produced acetaldehyde is subsequently reduced to ethanol, but some is required for cytosolic acetyl-CoA production for biosynthetic pathways. The enzyme is also one of five 2-oxo acid decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3) able to decarboxylate more complex 2-oxo acids (alpha-ketoacids) than pyruvate, which seem mainly involved in amino acid catabolism. Here the enzyme catalyzes the decarboxylation of amino acids, which, in a first step, have been transaminated to the corresponding 2-oxo acids. In a third step, the resulting aldehydes are reduced to alcohols, collectively referred to as fusel oils or alcohols. Its preferred substrates are the transaminated amino acids derived from threonine (2-oxobutanoate), norvaline (2-oxopentanoate), valine (3-methyl-2-oxobutanoate, also alpha-keto-isovalerate), isoleucine ((3S)-3-methyl-2-oxopentanoate, also alpha-keto-beta-methylvalerate), phenylalanine (phenylpyruvate), and tryptophan (3-(indol-3-yl)pyruvate), whereas transaminated leucine is no substrate. In a side-reaction the carbanionic intermediate (or active aldehyde) generated by decarboxylation or by activation of an aldehyde can react with an aldehyde via condensation (or carboligation) yielding a 2-hydroxy ketone, collectively called acyloins.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pyruvate decarboxylase isozyme 3
- Pyruvate decarboxylase isozyme 2
- Pyruvate kinase 1
- Fructose-bisphosphate aldolase
- Alcohol dehydrogenase 1
- Alcohol dehydrogenase 4
- Glucose-6-phosphate isomerase
- Transketolase 1
- NADP-dependent alcohol dehydrogenase 6
- Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
Sequence:
MSEITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISAQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIATAPAEIDRCIRTTYVTQRPVYLGLPANLVDLNVPAKLLQTPIDMSLKPNDAESEKEVIDTILALVKDAKNPVILADACCSRHDVKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAVESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDHMKIRNATFPGVQMKFVLQKLLTTIADAAKGYKPVAVPARTPANAAVPASTPLKQEWMWNQLGNFLQEGDVVIAETGTSAFGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIEKLIHGPKAQYNEIQGWDHLSLLPTFGAKDYETHRVATTGEWDKLTQDKSFNDNSKIRMIEIMLPVFDAPQNLVEQAKLTAATNAKQ
Protein: DEAD-box ATP-dependent RNA helicase 27 (EC 3.6.4.13) (Q9SB89)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ribosome biogenesis protein BOP1 homolog
- Pescadillo homolog
- Ribosome biogenesis protein WDR12 homolog
- AT5g04600/T32M21_200
- Probable rRNA-processing protein EBP2 homolog
- Transducin/WD40 repeat-like superfamily protein
- 60S ribosome subunit biogenesis protein NIP7 homolog
- Ribosome assembly factor mrt4
- KRR1 small subunit processome component
- Guanine nucleotide-binding protein-like NSN1
Sequence:
MANLDMEQHSSENEEIKKKKHKKRARDEAKKLKQPAMEEEPDHEDGDAKENNALIDEEPKKKKKKKNKKRGDTDDGEDEAVAEEEPKKKKKKNKKLQQRGDTNDEEDEVIAEEEEPKKKKKKQRKDTEAKSEEEEVEDKEEEKKLEETSIMTNKTFESLSLSDNTYKSIKEMGFARMTQIQAKAIPPLMMGEDVLGAARTGSGKTLAFLIPAVELLYRVKFTPRNGTGVLVICPTRELAIQSYGVAKELLKYHSQTVGKVIGGEKRKTEAEILAKGVNLLVATPGRLLDHLENTNGFIFKNLKFLVMDEADRILEQNFEEDLKKILNLLPKTRQTSLFSATQSAKVEDLARVSLTSPVYIDVDEGRKEVTNEGLEQGYCVVPSAMRLLFLLTFLKRFQGKKKIMVFFSTCKSTKFHAELFRYIKFDCLEIRGGIDQNKRTPTFLQFIKAETGILLCTNVAARGLDFPHVDWIVQYDPPDNPTDYIHRVGRTARGEGAKGKALLVLTPQELKFIQYLKAAKIPVEEHEFEEKKLLDVKPFVENLISENYALKESAKEAYKTYISGYDSHSMKDVFNVHQLNLTEVATSFGFSDPPKVALKIDRGGYRSKREPVNKFKRGRGGGRPGGKSKFERY
Protein: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial (PDP 2) (EC 3.1.3.43) (Pyruvate dehydrogenase phosphatase catalytic subunit 2) (PDPC 2) (O88484)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:9651365}.
Interaction partners:
- Pyruvate dehydrogenase phosphatase regulatory subunit
- Dihydrolipoyl dehydrogenase, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- [Pyruvate dehydrogenase
- Protein-serine/threonine kinase.
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- [Pyruvate dehydrogenase
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Sequence:
MSSTASYRIFNFARNRIAVLRGGRRLYSRAATSRNQVKWRLFSPASLAVNDSSPHGGFALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNSGVPNSVLRFESNQLAANSPVEDRQGVASCVQTRGTMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHKTLEQMEEAMENMKPLLPILQWLKHPGDSIYKDITSVHLDHLRVYWQELLDLHMETGLSTEEALMYSFQRLDSDISLEIQAPLEDEVTKNLSLQVAFSGATACMAHVDGVHLHIANAGDCRAILGVQGDNGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLLPCRAFGDVQLKWSKELQRNVLERGFDTEALNIYQFTPPHYHTPPYLTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLVVGHLSKVGHQKPALDQRPANLGHMQSLLLQRKASGLHAADQNAATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSESIDTYFKEG
Protein: Proteasomal ubiquitin receptor ADRM1 homolog (Proteasome non-ATPase regulatory particle-like protein 13) (Q09289)
Organism: Caenorhabditis elegans
Function: May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q16186}. Nucleus {ECO:0000250|UniProtKB:Q16186}.
Interaction partners:
- PCI domain-containing protein
- 26S protease regulatory subunit 6A
- 26S proteasome regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 8
- Probable 26S proteasome regulatory subunit 6B
- 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 14
- 26S proteasome regulatory subunit 8
Sequence:
MAAMFSNTRSVASSSGHIVEFKAGRSRLEAGSGDTMRKVVAEPKKGLVFIKQSNDMLIHFCWKDRETGAVVDDLIIFPDDAEFKAVPGCPDGKVYMLKFKSGDMKLFWIQDSTPDVDKDLVKKVTDALNKPPTSRPAASRSAGSNANTDRQSAGGSLISSSDMNAPLGGIDQGQLMSLIQSLQGGNSDTLPISSVPRGEDASSEADCEPSTNAAEEGSSNPLSLNNPAIQQIFNNLGRSQKKEVAVSLATALSNETVAEVARNHAEELAPHLPTSDDPARELSETVRTPQFRQAADTLGHALQTGQLGPVVAQFGMDEATVGSANQGDIRGFAANLTKAEGGEDAAKTQNSDDDATREPEPKRNRPDNEDMDVD
Protein: Bidirectional sugar transporter SWEET16 (AtSWEET16) (Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 16) (Q9LUR4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates both low-affinity uptake and efflux of sugar across the vacuolar membrane. Regulates sugars homeostasis in leaves and roots by exporting/importing them through the tonoplast regarding metabolic demand. Acts as a vacuolar hexose transporter, such as glucose (Glc), fructose (Fru), and sucrose (Suc).
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:24028846, ECO:0000269|PubMed:24381066, ECO:0000303|PubMed:25988582}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
Interaction partners:
- Sucrose transport protein SUC4
- Monosaccharide-sensing protein 1
- Sugar transporter ERD6-like 6
- At2g39500/F12L6.16
Sequence:
MADLSFYVGVIGNVISVLVFLSPVETFWRIVQRRSTEEYECFPYICTLMSSSLWTYYGIVTPGEYLVSTVNGFGALAESIYVLIFLFFVPKSRFLKTVVVVLALNVCFPVIAIAGTRTLFGDANSRSSSMGFICATLNIIMYGSPLSAIKTVVTTRSVQFMPFWLSFFLFLNGAIWGVYALLLHDMFLLVPNGMGFFLGIMQLLIYAYYRNAEPIVEDEEGLIPNQPLLA
Protein: Protein TILLER ANGLE CONTROL 1 (F4IJ79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the regulation of inflorescence branch growth angle. Promotes horizontal inflorescence branch growth.
Interaction partners:
Sequence:
MTIFNWVQKKLHQNVIKEIDGVRKNEKKKRNEGISEIEKNTKAILDQVGLVDALDNWFDGVLTIGTFGFDTLNFKEEDEMDDDECGSGDLDYVVIDGSIIKNVDQESDPLISVENKFYDHHEDVGNLYVQADTDHFGSIKTAETPAVTAAAEAEIEPQKKRTTLAELFMEDHDKGYDTWHCKKPNNPNLDGEEVKYYKQNGSKLSKRFSFVKKKLVMSKSKEEENDLRPIKKMRQMIKRMLKKKIHPDVDATKALKKDVPYKPTRNCEALESHYLLKIQDCVA
Protein: 116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP-specific protein, 116 kDa) (A8WFS1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
METDLYDEFGNYIGPELDSDEDEELDAEDRDADEADEEGDDDDQAEADEDGGGGGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVRMKQFTLMEQELPATVYDMEFLADLMDSSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRDDEDLRYTDILFTEQERGVGIKSTPVTMVLPDSRGKSYLFNIMDTPGHVNFSDEVTSAVRLSDGIVLFIDAAEGVMLNTERLIKHAVQERLAITICINKIDRLIVELKLPPTDAYYKLRHIVDEVNGLLSTYSTDESLIVSPLLGNVCFASSQYCICFTLGSFAKIYSDTYGDISYMEFAKRLWGDIYFNPKTRKFTKKAPNSNSQRSFVEFVLEPLYKILSQVVGDVDTSLPRVLDELGIHLTKEELKLNIKPLLRLVCNRFFGEFTGLVDMCVQHIPSPQGGARAKIEHTYTGGLDSDLGETMSECDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTLQAGQPVKVLGENYSLEDEEDSQICTVGRLWISVARYQIEVNRVPAGNWVLIEGCDQPIVKTATITEPRGNEEAQIFRPLKFNTASVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGIGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDTTGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPLHRGGGQVIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFALSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVMLNYPM
Protein: Autophagy-related protein 23 (Cytoplasm to vacuole targeting protein 23) (Q06671)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9. Also plays a role in regulation of filamentous growth.
Subcellular location: Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Note=Found in pre-autophagosomal structure and other punctate structures. Correct localization of ATG23 to the membranes is strictly dependent of ATG9. Cycling through the pre-autophagosomal structure and correct location to other punctate structures is ATG1- and ATG13-dependent.
Interaction partners:
- Autophagy-related protein 27
- Autophagy-related protein 9
- Serine/threonine-protein kinase ATG1
- Autophagy-related protein 13
- Autophagy-related protein 18
- Autophagy-related protein 11
- Autophagy-related protein 29
- Autophagy-related protein 19
- Autophagy-related protein 3
- Autophagy-related protein 17
Sequence:
MELNQVLEKKEQILQYLGTLVGLHEKALSDVNSASQVTSIRKDITICLNDLCRINDLLVSHDGLLKREIGSLLRDKQELLELNEREQLLWKERKSWHIKQETDAAPADYVIDKDAIITISSHHRTSLNKYIESVGAENTILSNTDDSDAMIEEVQNAESSADQMIRNYKLLQLSHKQAKSEIIRLETLLRDFKKDNKFIEEELKRQSGRIRSEMGNIDFHLSKIEESKHQLMKRIGFESPLTQEKSLSEKIFNLRLSSADEDYNERQTINMKNFVHMKDLIELKIEDLQEQLMRNKNESSTVLTQRELWLDCQKKVGDLESKLITKLRSSSNSKIPPNEMSEMINSTIQYLNNLLDSSDEKLTTTLISNERDVLSKACEELHSESTTAQDGSSALPSKPIDIHKSHKGSNASSNLKQPSTPSFLVASKSPPKIGISESVVNANKNDAISKKVE
Protein: Rho guanyl nucleotide exchange factor (Rom2), putative (Q4WUI2)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- Rho GTPase Rho1
- WSC domain protein, putative
- Rho GTPase activator
- Actin-related protein 4
- Transcription factor rlmA
- Rho GTPase Rho 2, putative
- Protein kinase C
Sequence:
MADLGGQQGRNYRPYGHASSFQRDAAFSEIFGGAPPPGRSQTMNSQTPQFSQDRAHTMSSHVPHPQMQRPPPQPARQGPNGYTPAAPNGHYQAYPGPAAMAQQSSHNPPRPYPGRYVYPQPQRLDSRPAPGPQYPDVKGYGRPMPPPALNSDAYRSRSMARMGGPPGYQQPPLSSFNHTSASAFRQQPYSSTTPVTDQGRVVPVRHANERAMSLTSYSMDRDHSHTTQTGRVIPTRRQPSGPSQPPTRHFEEEPAIVHHVNGRPRPPSDGSTNSRAMSMASTIVPDRTMSMQSQMTHRPSNQTTLVSNNSRRSKVPLVYPALLSRVADVFRERIPLGERQKNGLSYQNAFSGAEAVDLIAHIIKTNDRNLALLLGRALDAQKFFHDVTYDHRLRDAQGEIYQFKETMGEEAPSSEVNGVFTLLTECYSPTCTRDSLCYSIACPRRLEQQARLNLKPQPGLRTSASKASLHGDDDNDNQKLWINMVPKEVSDSIDDREKKRQEIIFEIMYTERDFVKDLEYLRDFWMRPLRAAGNANQSPIPEHRREKFIRTVFGNCLEVLKVNGALCEALNSRQKESPVVKTVGDIFLQHVPNFDPFIKYGANQLYGKYEFEKEKASNPAFARFVEETERLKESRKLELNGYLTKPTTRLARYPLLLEQVVKNTKDDNPDKEDIPKAIKLIKDFLSRVNTESGRAENHFNLVQLNSALKFNPGDYVDLKLTEENRQMLTKMAFRKAPTDSSEVTAYLFDHAVLLVRIKVVNKREEYRVYRKPIPLELLVIAQMDEVIPKVGVPKRPSSSLLSNKPAANPPSTKEGLPITFRHLGKGGYEQTLYATSPTQRRKFIEMVEEQQRKLRERNSNFYNKTVLCSNFFTSANRVNCLVPVDGGRKLVYGTDSGIFISERWPKDKSAKPRRVLDASQVTQIDTLEEYQLLLVLANKTLSSYPMEALELAEGQNSVAKRPKKIQGHANFFKAGIGLGRHLVCSVKTSALSSTIKVYEPMDNLAKGKKKSAVSKMFQSGQDTLKPFKEYYIPAESSSIHFLRSTLCVGCARGFEVVSLETTETQSLLDQADTSLDFVARKENVKPIHIERMNGEFLLNYSDFSFFVNRNGWRARPDWKISWEGNPNAFALSYPYILAFEPNFIEIRHIETSELIHIMTGKNIRMLHSSTREILYAYEDEGGEDVVASLDFWNKPQQQQ