wanglab/gogpt-training-data huggingface dataset:
Protein: TOG domain-containing protein (Q583M5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Serine/threonine-protein kinase, putative
- Tubulin alpha chain
- End-binding protein 1
- Calponin-homology
- Rev7, putative
- Uncharacterized protein
- Dynein heavy chain region D6 P-loop domain-containing protein
- Epsilon tubulin
- Tubulin beta chain
- Zeta tubulin
Sequence:
MTNNEGSISPSHSLPNFLMLDAVEEDFTNLPLDSLLLHKNWKGRKAGFEQVRDQPKELRIHLLNKPKKIYAEQNIAAQEALFEALAALVPFCDNDELDVLAGEPLRVVVEKGLTGRSKAAQASFAFALDLVGAGKQTHVFNVLLPAVAHKTPKNRIAATQLCGHIVDLFGVHGLPAKALLKAMQPLFNDPNPQVRKEAANLCCHCYSYIGAGVKSCLTDLREVQLQELEKQFENIVLGRVPRRNIKGIETSTPIKSVAPIVGIASRTDRSNDLDDDAYAACSEEPVVSKIPRTFYLTALDRSARWQDRVAAVQETVLPLISVPKIRQKDDYHELCTMIREYLVDPQAPLMLVGFKCIQEMARSLRNAFAPYARTYLNPLFEKMKDKKTSVVEHVTTTLESLIRYHCITLDQCHDEIDVTLQSRVPNQRLALIQWLSRLTDKLEPTCFNRICRAQPMLSRVLNDEKIENREAAYIFVAKLMALNGEEHFQALLVSLDEKQRAKLVAIINSAANMQCTPSSSPARKAPRLEQRCESIGQRPHSSSVASSCSRSSVCGARGGRLGRALSHNKSLPEQPRVSGMEDAVTLESMLPSKDEAFNLILGLLGGDMTVSVLLTAKEWSSRHCGVLKVKNMVVGWSEKESTDYLDHVVVYLRVDPGWRESIFQVFNAMASVLQEVVNKASKVSPGAGHAIISGCLGRLTDQKSKSVVCDLITSLTKSLGAAFVLRHVVGTLVQIKTPKLLHESNVFMTQLLRSTTVSPSDAKCVVDYVNNHCAEHLFPTVRTTGATLLAIITAGSVASNEDTLEQSANTLGQSENTSLNGTVANASRTGPRREASQASTVTSYQPVRERDENERLRTNSVTTNATEVKPTSHPRHAHVEASRLNSCDKHKKMSAAVDDEENHEAVDIGPQLTLLAKQITGAPDWRTRLEGVKKVEELVFASNKRICPNGVTEIIGALRSRFDETNKNIVVDALRIISLVVEAAGFSASRTGVKGLVQRLLGMLGDQKVNLREEAARLAGIALDCLGLEPILQHIQKPLMAESHTSNLVALGLIEKGLEQNTEGNVSRRAVNSLVPTIVRLCMSRILEVRSAAERVIGHVLPFVGEETVLRSVKNLRPAEQQSVMALLGRQLQHALRNGSDEGTRAPSVCLNNSTSPRCSNSSPRSQCSSRAGARESCANLRSLEVSGVVPPGKIPHMNLPIIQAQSASEASLTSVTAASARNAQGFSRNEELLSIQEMMVGLRSASATAAMAACSEFLQRLPNGEDCGTPEMIHVMVERLHDNIKQLNVELALDIIRCLKATFETERCAQRCHTSLLFRMLGMIFECLLSESFSLHSNVIKALNNTTLTLLERCPPNDVFSALMSRMTMYSSTYIENGTKPSLKYVQVTVKCLMRLGFTSISPENVIVCCHEYLLQHPPTAFRNLDDISIRTVKTILQDFCRRYGLSLLEMTNKLVGSQNLVSHFIRSCLDVEEQIAQRDNVKDPNRKVEYLQQSRKVTEKGAAATQNEQVNNQKKGAQHVDPQTYCTSRGSLSESAAPDDASVVGIFSRIRNHETTNSGIEELYQFIKCHPRSPTFEKQFRRCSEAFRSYIKRKMESQMMKDDDKPPGFALPEILRLTA
Protein: Myocyte-specific enhancer factor 2D (O89038)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).
Subcellular location: Nucleus. Note=Translocated by HDAC4 to nuclear dots. {ECO:0000250}.
Interaction partners:
- Myocyte-specific enhancer factor 2A
- Myocyte enhancer factor 2B
- Nuclear factor of activated T-cells, cytoplasmic 3
- Nuclear factor of activated T-cells 2
- Nuclear factor of activated T-cells 1
- Nuclear factor of activated T-cells, cytoplasmic 4
- Myoblast determination protein 1
- Myogenin
- Histone deacetylase 4
- Mitogen-activated protein kinase 14
Sequence:
MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSSVPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGRDLNSANGACPNPVGNGYVSARASPGLLPVANGNGLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLPSAELSSLPAFSSPAGLALGNVTAWQQPQQPQQPQPPQPPQSQPQPPQPQPQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK
Protein: PX domain-containing protein EREL1 (Protein EREX-like 1) (F4JTJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as an effector of RABF2A and RABF2B (By similarity). Involved in vacuolar transport of storage proteins. Regulates membrane trafficking to protein storage vacuoles (PSVs). Binds specifically to phosphatidylinositol 3-monophosphate (PtdIns3P) (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:27288222}. Endosome membrane {ECO:0000269|PubMed:27288222}; Peripheral membrane protein {ECO:0000305}. Note=The endosomal localization depends on the active state of RABF2B. {ECO:0000269|PubMed:27288222}.
Interaction partners:
- WD40 repeat-containing protein HOS15
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 10
- ADP-ribosylation factor C1
- Transcription and mRNA export factor ENY2
- Ubiquitin C-terminal hydrolase 22
- Hyperosmolality-gated Ca2+ permeable channel 4.1
- Vacuolar sorting protein 3
- Transcription initiation factor TFIID subunit 5
- Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog
Sequence:
MMQRRSPPKHRHDGTSPLPLGMDWSPPPRKWNGRDTVWPHDPRTGWSYCVTIPSWIVLPKSRNSDPVVFYRVQVSVQSPEGITTMRGVLRRFNDFLKLLTDLKRTFPRKGFPSAPPKGLLRMKSRAVLEERRCSLEEWITKLLSDIELARSVVVASFLELEAAARSACQDVDQNASDSNNDRSSTSSSPMVHPSLSLFHAGGSTLTSDYGSDTAYETSEVGSPSVGQDDISEIGTEDLTLDEDLTLTNPIEKLVNFSMSNIDEGLSMSETILEQLEDFPKHKVRSRYVNNILGKDVYNGNASKGVFLANNGSRLLSEPEPSTHSVMHDRNDSAERFALHTGQTSTSGLLISSRDSHLDLRQGPGVSLGTGLVCNPERQGSAQIVLPLELRNKLNRILLATNERLVNAKTDMEDLIARLNQEIAVKDYLNKKVNDLEGELETTKQRSKENLEQAIMSERERFNQMQWDMEELRQKSYEMEMKLKSREDGSSHAEPTVQSTISEKHVLSKELDARKQQLEDLSRRYEELEAKSKADMKVLVKEVKSLRRSHVELEKELTHSLTDKTNAEKLLQEERKLLENTVAARKKLLSDCRILHDRLKEYNLNLSMDGNGNFVDDSTTISDVLRLLSISDDQIEEAQLLSGFDENAAAEDIDKTLSMDTETRIMEDELRKILANIFVENAKLRKQVNSAMLRALQKDVKTTEDVNEENSDEKDEASRETLKR
Protein: Thioredoxin-like protein AAED1, chloroplastic (AhpC/TSA antioxidant enzyme domain-containing protein 1) (Q9ZUU2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Thioredoxin family protein
- Sulfhydryl oxidase 2
- Peroxidase 18
- Protein SUPPRESSOR OF QUENCHING 1, chloroplastic
- Cytochrome c-type biogenesis ccda-like chloroplastic protein
- Thioredoxin-like protein HCF164, chloroplastic
- Thiol-disulfide oxidoreductase LTO1
- Probable protein phosphatase 2C 26
- Peroxidase 65
Sequence:
MAIALSSSSTITSITLQPKLKTIHGLGTVLPGYSVKSHFRSVSLRRSAVVVSAITGASSGAGIGKGTADSLDTVKVLDLRGNEIPISDLWKDRKAVVAFARHFGCVLCRKRAAYLAEKKDVMDASGVALVLIGPGSIDQANTFVEQTKFKGEVYADPNHASYEALEFVSGVSVTFTPKAAMKILESYMEGYRQDWKLSFMKDTVERGGWQQGGILVAGPGKDNISYIRKDKEAGDDPPVEEILKACCA
Protein: Inactive GDSL esterase/lipase-like protein 25 (GDSL-like lipase 25) (Myrosinase-associated protein GLL25) (Protein ENDOPLASMIC RETICULUM MORPHOLOGY 3) (Protein GOLGI DEFECTS 36) (Protein MODIFIED VACUOLE PHENOTYPE 1) (Protein NUCLEAR CAGE) (Q7XA74)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in organization of the endomembrane system and is required for endoplasmic reticulum morphology and organelle distribution. May act by inhibiting the formation of PYK10 complex by binding to GLL23 and exporting it from the ER. Required for proper subcellular localization of myrosinase TGG2. Has no lipase or esterase activity.
Subcellular location: Vacuole. Endoplasmic reticulum. Note=Also found in ER bodies. Retained in the ER when mutated.
Interaction partners:
- Myrosinase 2
- MD-2-related lipid-recognition protein 3
- Myrosinase 1
- Membrane protein of ER body 1
- TSA1-like protein
- Beta-glucosidase 23
- Protein transport protein SEC24 A
- N-
- 3-isopropylmalate dehydrogenase 1, chloroplastic
- 3-isopropylmalate dehydratase small subunit 3
Sequence:
MLLIPSFTANSNEPPPSKLSLSDLSMAILKSHFFLLFPLLLLHFHTVSFAQTLFVFGDGLYDAGNKQFLSQNRVDASFPPYGVTVGQATGRWSDGSIVPDYLAKFMGIPKISPILLTTADFSHGANFAIADATVLGSPPETMTLSQQVKKFSENKNKWTNQTRSEAIYLIYIGSDDYLSYAKSNPSPSDTQKQAFVDQVITTIKAEIKVVYGSGGRKFAFQNLAPLGCLPAVKQASGNVQECVKLPSEMAALHNKKLLQLLVELSRELNGFQYSFYDFFSSIQNRVIKSKTYTFETGNAACCGTGSINGSNCSAKNVCAKPEEYIFFDGKHLTQEANLQVGHLMWGADPEVIGPNNIRELMVLPLDITVILAGIQEAMAAMRPRQSNIESLYDIKKMESEMDNHWLYQVDKAISFMI
Protein: L-arabinose 1-dehydrogenase (NAD(P)(+)) (EC 1.1.1.376) (D-galactose 1-dehydrogenase) (EC 1.1.1.120, EC 1.1.1.48) (Q53TZ2)
Organism: Azospirillum brasilense
Function: Catalyzes the NAD(P)(+)-dependent conversion of L-arabinose to L-arabino-gamma-lactone. Is involved in a degradation pathway of L-arabinose that allows A.brasilense to grow on L-arabinose as a sole carbon source. Prefers NADP(+) to NAD(+) as electron acceptor. Displays high catalytic efficiency for both L-arabinose and D-galactose in vitro. However, the enzyme appears to be involved in the metabolism of L-arabinose but not D-galactose in vivo. To a lesser extent, is also active on D-talose and D-xylose as substrates in vitro, but not with D-arabinose, D-glucose, D-ribose, L-xylose, L-mannose, L-lyxose, and D-fructose.
Interaction partners:
Sequence:
MSDQVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKEDVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFGR
Protein: Piwi-like protein 1 (P90786)
Organism: Caenorhabditis elegans
Interaction partners:
- Argonaute protein hrde-1
- Staphylococcal nuclease domain-containing protein 1
- Guanyl-specific ribonuclease pgl-1
- ATP-dependent RNA helicase glh-1
- NFX1-type zinc finger-containing protein 1 homolog
- Small RNA 2'-O-methyltransferase
- RNA-directed RNA polymerase
- Endoribonuclease dcr-1
- Argonaute protein wago-1
- Exonuclease mut-7
Sequence:
MASGSGRGRGRGSGSNNSGGKDQKYLGTIQPDLFIRQQGQSKTGSSGQPQKCFANFIPIEMTQSDYSIYQYHVEFEPTVDSKANREKMLRDNNVTDEIGHHFVFDGMILYLKEEWEQNQMIEVQHPIDRSLICIRFKQTNRFLVDDPQTINIFNTIIRRSFDALQLTQLGRNYFNWGDSRAVPDYNMSILPGYETAIRMYEENFMLCVENRFKMVREESMYILFHKELRSCQNNPQRVQEKMNEMYGGTTIITRYNNKLHRYTRLDYSISPLSEFVKDGQSITLKEYFKNQYGIEITVDDQPIIISEGKPKQPGEPPQVSYIVPELCFPTGLTDEMRKDFKMMKEIAKHTRMSPQQRLVESRKLIVDLSKNEKVMECFKYWGISLGQDLANVQARVLKSEPLQGKKTYEGKQAEWARGVKECGIYRGSNMTNWIVIGPGSGNSGLLSQKFIEEARRLGKILQVQLGEPMCVPIRGISPNDYLEGVKGAIKQVDGEDIHMLVVMLADDNKTRYDSLKKFLCVECPIPNQCVNLRTLAGKSKDGGENKNLGSIVLKIVLQMICKTGGALWKVNIPLKNTMIVGYDLYHDSTLKGKTVGACVSTTSNDFTQFYSQTRPHENPTQLGNNLTHFVRKALKQYYDSNDQTLPSRLILYRDGAGDGQIPYIKNTEVKLVRDACDAVTDKAAELSNKVQEKIKLAFIIVTKRVNMRILKQGSSLDNAINPQPGTVVDTTVTRPERMDFYLVPQFVNQGTVTPVSYNIIHDDTDLGPDKHQQLAFKLCHLYYNWQGTVRVPAPCQYAHKLAFLTAQSLHDDANGCLRDKLFFL
Protein: Stretchin-MLCK (Q9NBC4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
DNVIIFCEVVGDPKPEVVWLRDFLNPEYYKDAPHFRRIGDGPEYRLEIPSAKLDFTGTYSVIASNCHGETKAVISLQIFAKDILNKSRMDKVHTRHGNIETLPRFVRNLRNLRCCDGDAISLECHVEA
Protein: Rhoptry neck protein 2 (Q8IKV6)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Apical membrane antigen 1
Sequence:
MLKFFIFILHIYLYIDSIYSSELSKHVKHDTDELKYASPTYDPKKGTKVIFYMPGNEQGVIPNNIQNKQHGTSIYPAIEYPTTKYPAIEYPGSEMNNGKTGTTNSGIYNKAHGSSNDYNASNSQDKTINLHIDENNSNNSYQPYDSNNTNNNTNSNNNSNNNSNNNSNNNSNNYSNNNSNTNSNTNSNTNSNNNTTNYDLNSEYEKIRRKEEEAARRIERERRADINRKNQDNNSNKYNNEQNGGYESDGNSPNSRVNINITNNGTHGNPHNNNSYGHKNNMHNTTNGNYANGNYANGNYSKGDYTNGDYTNGDYTNGDYTNGINNNMHGKNNYNTANGEYVNGAYDGLNNGSYKLIGNLNNNQNVDNSYNQGNENDKTYTSNYNINLEDNKNSPDNNQNYISTFNKDIGPNKSERSYYDVYGREYDDNKYNPYNKTNNHNTNQNGSTTYGSNANGTYGPNGTYGSNGTYEPNESYGPNGAYGPNGTYGHNGKYGSKGTYGNNETPYYVEHPEYDNGKSMSDFHVKDSKDNIGPGGDYPNLYQNIYGNEKNPNIFPGSPRNINVYSVHHIPNNGANGGLNSGANGGLNNGANDGLNNGANGGLNNGANGGLNNGANGGLNNGMNNGMNNGMNNGMNNGMNNGMNNGMNNGTNGGLNNGMNNGMNNGMNNGMNNGIHDDLYNSENSTFNNGLNNSGRTGLNNAYPHNGMLNNGTEYNVHYGNSDSNNTNDSMLNENYYSDSDYDDHTPGNKKKVYKSVAERNKKSASQDSLGAGFSDSDSDSEYEVVDGENKKYKKKNKENNEKDKYENNWDSNNYNSDNEIKDGYLSESEREYARNKANEIEDKMKKGEYSRKYKNSKSNESGYASKQTSDSDDSDIEANAFYVDNGQEMLIKEKEHYSSDSEHHKEESASIGNLNVFFPAENYHFSTYMGFDRRSFLPSNEIELEKMIGANFSNEVKNYCSRQNVAQKIGDYLNISFEYSRALEELRSEMILDFNKRKHLTNNTDDTILHMIENAEKRKNDPNYKEAYENKDYANNANIFMNEYSNPLSTKYNKILKEYLCHLFVNNPGTKPLERLYYNSLALGELVEPIRNKFKSLASSTIDFNYEIHMASASNIYLLAHFLVLSLAYLSYNEYFTTGTKSFYSLPTILTANSDNSFFMLNEMCNIHYNPNKNFKKDITFIPIESRPKRTTTFYGERRLTCDLLELVLNAIMLININEINNVFSNNNVDGYENSLSFSHNAIRIFSKVCPKINNDNVLKCEFEESSLYNPKIIKNDTSEKSSQKNLKKAFDLLRTYAEIEGHSAEGSTSPYYVSLILDDMKYNDFYKYTLWYEPRELIYGDIRGMQMKKKKKTKYIYNDFMKKSTQLKKKLIKNDLKYNLKSKGLVFLYAMIDKYGSILNKSQKAKVQFLNSTSSIRYYLYLNKVIFKSAKTYLDIMKRVLEELQTSTNTPLKFLVRGNYIENINNIARNDNMFYANLFVLTALSRRDPVKDYYNDKRKMLSATLAEKFANSTSMLIPHKLRKLVVSMKKGLLKKKLLTSLAKVKLLQHIPAHMLENITSSIRFTTHTIATMQIIQNAKYMSKHNFSQYDSKGMLARQIFTKGGFAEYADNLMAKWFSKGFEEYKREQIENFKMENSIDSELKDSEREDENDSSEESAKKKLQDLQLEEREKMKKENSLLFNQSDKWDQFINKELVRALGLWLEFNDNPTNASSFVYKVVEDSKHLLENNIDNNIIFSRTVKPTKQTAFRRFFNKILSLGNMLLRKPSFRVEHALWFGATIDIKKAFILLEKVSELHKMLNNQDESWLINEAFIEIVDHVVDLSTYKHVREPFGVARNPGMMAINPKYAELSHENRLRELQNSMCADHCSSVWKVISSFALHHLKNPDSLHTYESKFSKNSFGNKIDDKDFVHNFKMILGGDAVLHYFDNLLPKTMKKDLKAMKYGVSLTSAYSLKLTKIIFSQMQLPYLSQMFYMQAPYFGHFIGKWQKKRQQSRLKEIMSFMTLGSLSAYTLFSAMDITQQAKDIGAGPVASCFTTRMSPPQQICLNSVVNTALSTSTQSAMKCVFSVGLFASIGPYLFAPMAGLAVWNILKSEFKVLQRIDMALKNVFKNMWNKFLSLKGISKLRGIFKRKKAMKKKIIENATRKMNDMKNNPEKAKAHKMALKKINNYSKGSYHYISYAKIRI
Protein: Small ribosomal subunit protein eS24B (40S ribosomal protein S24-B) (O59865)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS13B
- Small ribosomal subunit protein eS10B
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein eS28A
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS9A
Sequence:
MSEAVTIRTRKFMTNRLLQRKQMVVDILHPGKANLSKNEIREKLAQMYKTDSECVQAFGLRTHFGGGRSTGFALIYDSTESMKKFEPHYRLVRVGQAEPIQKVARQQRKQRKNRGKKVFGTGKRLAKRKSKQQD
Protein: Laccase-1 (EC 1.10.3.2) (FpLCC1) (S8FIE4)
Organism: Fomitopsis schrenkii (Brown rot fungus)
Function: In vitro, has activity towards 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), 2,6-dimethoxy-phenol, and guaiacol. Although brown rot fungi preferentially degrade hemicellulose and cellulose, the enzyme may contribute to generating small amounts of lignin breakdown products required for catalytic reactions.
Subcellular location: Secreted {ECO:0000269|PubMed:34116754}.
Interaction partners:
- Nitrate reductase
- Solute carrier family 40 member
- Uncharacterized protein
Sequence:
MAFTAISLFLAALGVINTAFAQSAVIGPVTDLDIINAEVNLDGFPRQAVLAGGTFPGPLIKGNKGDNFRINVHDFLYNETMDVTTTIHWHGIFQRHTNWADGPAFVTQCPIAPGNSFLYNFTVPNQAGTFWYHSHEGLQYCDGLRGPFVVYDPEDPHRDLYDVDDESTVITLADWYHEAASLIVPPADPDSVLINGRGRQANDTTSPLAVINVEYGKRYRIRLISVSCDPYFNFTIDGHNFTIIEADGENTDPLPGVDQIQIFAAQRYSFILDANQPIDNYWIRVIPEQVGANGTAATPPGLAVLHYLGAPPFDPKANASQVPISVNPLLEQNLHALGATGVPDLDPSCAECNITLDFTFNTPLFFVNGVTYKSPTVPVLLQILNGSFTAQDLMPEGSVYTLPRNKTIQINMPGGVLGIPHPLHLHGHSFSVIRSANSDETNLYNPVRRDTVSIGTNGSFVAIRFTTDNPGPWFLHCHIDFHLAAGFAVVMAEDPMDVPGYVKPIPPAWDKLCPIYDALPANEQILQPEAANLSTYPQK
Protein: Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (Q6Q418)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MSHRKFSAPLHGSLGFLPRKRCKRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTVVETPPMIVVGVVGYVMTPRGLRSFKTIFAEHISDECKRRFYKNWYKSKKKAFTKYCKRWQDEEGKKQLEKDFSSMKKYCQIIRIIAHTQMRLLPHRQKKSHLMEIQLNGGTISDKVDWAREKLEQSIPIANVFSQDEMIDVIGVTKGHGCKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGVGYHNKDGKLVKNNASTDYDLSNKSINPLGGFVHYGEVTNDFLMLKGCVVGTKKRVLTLRKSLLVQTSRRAQEKIDLKFIDTTSKFGHGRFQTIEEKKTFMGPLKKDRLAKEEMA
Protein: Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) (P67963)
Organism: Xenopus laevis (African clawed frog)
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly (By similarity). Phosphorylates protein custos.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P48729}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:P48729}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:P48729}. Nucleus speckle {ECO:0000250|UniProtKB:P48729}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q8BK63}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q8BK63}.
Interaction partners:
Sequence:
MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKSKSNMKGF
Protein: Covalently-linked cell wall protein 12 (Protein Alpha0.6) (Q12127)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the cell wall. May play a role in the formation of a tightly packed outer mannan layer, which protects the inner glucan.
Subcellular location: Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase 3
- Phosphoglycerate mutase 1
- Cell wall protein SED1
- Covalently-linked cell wall protein 14
- Cell wall protein CWP2
- Chitin synthase export chaperone
- Cell wall protein SRL1
- Protein ORM2
- Fructose-bisphosphate aldolase
- Cell wall integrity sensor MID2
Sequence:
MQFSTVASIAAVAAVASAAANVTTATVSQESTTLVTITSCEDHVCSETVSPALVSTATVTVDDVITQYTTWCPLTTEAPKNGTSTAAPVTSTEAPKNTTSAAPTHSVTSYTGAAAKALPAAGALLAGAAALLL
Protein: Mas-related G-protein coupled receptor member X1 (Sensory neuron-specific G-protein coupled receptor 3/4) (Q96LB2)
Organism: Homo sapiens (Human)
Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Pro-FMRFamide-related neuropeptide FF
- Gastrin-releasing peptide
- AP-1 complex subunit beta-1
Sequence:
MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNAFSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTERCLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFITVAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFLWIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASEVDEGGGQLPEEILELSGSRLEQ
Protein: F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx) (Q9CPU7)
Organism: Mus musculus (Mouse)
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q969P5}. Nucleus {ECO:0000250|UniProtKB:Q969P5}. Note=Shuttles between cytoplasm and the nucleus. {ECO:0000250|UniProtKB:Q969P5}.
Interaction partners:
- Cullin-1
- S-phase kinase-associated protein 1
- Myoblast determination protein 1
- E3 ubiquitin-protein ligase TRIM63
- F-box only protein 25
- Growth/differentiation factor 8
- Myogenin
- Eukaryotic translation initiation factor 3 subunit F
- Forkhead box protein O3
- Forkhead box protein O1
Sequence:
MPFLGQDWRSPGQSWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYSKENLFSSLNYDVAAKKRKKDIQNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNSIQISRPAFKGLTITDLPVCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKRLCQYHFSERQIRKRLILSDKGQLDWKKMYFKLVRCYPRREQYGVTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
Protein: Probable ion channel SYM8 (DMI1 protein homolog) (Q4VY51)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: Required for both rhizobial and mycorrhizal symbiosis. Involved in Nod-factor-induced calcium spiking. May induce a change in membrane polarization that activates the opening of a calcium channel required for calcium spiking. Might be calcium gated.
Subcellular location: Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MAKSNEEPNSNLNTNKPPLKRTKTLAQQPSLNLRVSIAAADNGIGNSSSSSTKTDFEQQQRNYPSFLGIGSTSRKRRPPPPPKPSNITPNVKPPASDFQTKPHSEPKTSPSSSSPPSLPIAITKQQQQQHSISSPIFYLFVITCVIFVPYSAFLQYKLAKLKDMKLQLCCQIDFCSGNGKTSLQKDVVDDGSFSYYILNADSRTISLYIVLFTLVLPFILYKYIDYLPQMINFSRRTNSNKEDVPLKKRVAYMVDVFFSIYPYAKLLALLFATLFLIAFGGLALYAVTGGSMAEALWHSWTYVADAGNHAETEGMGQRIVSVSISAGGMLIFAMMLGLVSDAISEKVDSLRKGKSEVIERNHVLILGWSDKLGSLLKQLAIANKSVGGGVIVVLAEKEKEEMEMDIAKLEFDFMGTSVICRSGSPLILADLKKVSVSKARAIIVLASDENADQSDARALRVVLSLTGVKEALRGHVVVEMSDLDNEPLVKLVGGELIETVVAHDVIGRLMIQCALQPGLAQIWEDILGFENAEFYIKRWPELDGLLFKDILISFPDAIPCGVKVSADGGKIVINPDDNYVLRDGDEVLVIAEDDDTYAPGPLPEVRKGYFPRIRDPPKYPEKILFCGWRRDIDDMIMVLEAFLAPGSELWMFNEVPEKQRERKLAAGELDVFGLENIKLVHREGNAVIRRHLESLPLETFDSILILADESVEDSVAHSDSRSLATLLLIRDIQSRRLPYRDTKSTSLRLSGFSHNSWIREMQQASDKSIIISEILDSRTRNLVSVSRISDYVLSNELVSMALAMVAEDKQINRVLEELFAEEGNEMCIKPAEFYLFDQEELCFYDIMIRGRTRKEIVIGYRLASQERALINPSEKSMTRKWSLDDVFVVIASGE
Protein: Uncharacterized protein At5g39520 (Q0WW43)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein CHLOROPLAST VESICULATION
- At1g09500/F14J9_16
- von willebrand factor A domain protein
- F18B13.24 protein
- Mitochondrial arginine transporter BAC2
- Cytochrome P450 76C2
- DNA binding / transcription factor
- Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial
- Late embryogenesis abundant protein
- Phospholipase A1 PLIP3, chloroplastic
Sequence:
MAVSSAVYSCPGMIGSCGQVRSKRWRVKCHLSPVKSAKYSSKISTDIALHESPQALFDEYLEDKSRVFEAMFPDKPKNYRLNEEEWRIQMLPIKFFFLTACPVVVMRIRCKSNGQDYPSDVPLHITKVLELNMTKWELQGLDRVMEPTDFTLGVKGALYPDRRGRHTRLKGRLETTISFVLPSVLALVPEDVRRNMANAILAGLVDNMKHRVIESLVADYSKFKYERKKH
Protein: Os04g0493100 protein (cDNA clone:001-025-C01, full insert sequence) (cDNA clone:J033055B08, full insert sequence) (Q7X7U7)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MMMTEVANHSKRNHNESYFTGKAAVTSSSEEFGSMTSKKPRNTSPRDAPVSPKEKKDKIGERVAALQQLVSPFGKTDTASVLQEASGYIKFLHQQLEVLSSPYMRAPPVPGAAPEDPDHYSLRNRGLCLVPVDQTLQLTQSNGADLWAPANTTRRR
Protein: Large ribosomal subunit protein eL19 (60S ribosomal protein L19) (P36241)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small ribosomal subunit protein uS13
- GEO07453p1
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL33
- Small ribosomal subunit protein eS17
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS7A
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS4
Sequence:
MSSLKLQKRLAASVLRCGKKKVWLDPNEINEIANTNSRQNIRKLIKDGLIIKKPVVVHSRYRVRKNTEARRKGRHCGFGKRKGTANARMPTKLLWMQRQRVLRRLLKKYRDSKKIDRHLYHDLYMKCKGNVFKNKRVLMEYIHKKKAEKQRSKMLADQAEARRQKVREARKRREERIATKKQELIALHAKEDEIAAKAATAGH
Protein: STATHMIN-19 (Q9GQR3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
KKVKFITTEIRCQEKSRGGLSYEVILAEPAPNVAVPKRPVTPGKNVSVEEIEQKLKAAEERRISLEAKKMADISTKLAKVEEATRKKDEITNEFITQTKEQLESKMELHVEKREAIISDMKEKLKIHAQDIEKTRETLEQQKANEQKAIEEKLKIAQSLRDENIKKMLDRLKEHNTIKIAEIKSQNDQLECQKIEEKARIYENKLFAAEQKREKELQKKIEKVQKLERRAELVRQNKAQAQDLDGQQSAIASSG