wanglab/gogpt-training-data huggingface dataset:
Protein: Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (PH and FYVE domain-containing protein 1) (Phafin-1) (Zinc finger FYVE domain-containing protein 15) (Q96S99)
Organism: Homo sapiens (Human)
Function: May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Subcellular location: Nucleus {ECO:0000269|PubMed:16188880}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:16188880}. Lysosome {ECO:0000269|PubMed:16188880}. Note=Translocates to lysosome during apoptosis.
Interaction partners:
- Gamma-glutamylcyclotransferase
- E3 ubiquitin-protein ligase TRIM11
Sequence:
MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS
Protein: Actin filament-associated protein 1-like 1 (AFAP1-like protein 1) (Q8TED9)
Organism: Homo sapiens (Human)
Function: May be involved in podosome and invadosome formation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21333378}. Cell projection, podosome {ECO:0000269|PubMed:21333378}. Cell projection, invadopodium {ECO:0000269|PubMed:21333378}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:21333378}.
Interaction partners:
- Growth arrest and DNA damage-inducible protein GADD45 gamma
Sequence:
MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTADLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYNDSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQLTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQSREQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNSFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
Protein: Trifunctional enzyme subunit beta, mitochondrial (EC 2.3.1.155) (EC 2.3.1.16) (TP-beta) (B5MD38)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
Protein: WASH complex subunit 2A (A0A087WYF6)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004146}.
Interaction partners:
Sequence:
MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHEIKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTNEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
Protein: Protein PSK SIMULATOR 2 (AtPSI2) (Q9SA91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes seedling growth probably via the regulation of phytosulfokine (PSK) signaling; PSK are peptide phytohormones acting as growth factors. Involved in PSK-induced root growth. Together with PSI1 and PSI3, required during vegetative growth and reproduction.
Subcellular location: Nucleus {ECO:0000269|PubMed:25062973}.
Interaction partners:
Sequence:
MGGVCSCVFKDDDKKKKLRSNDDDKSRGFSGKLKSMRRSKTSDSYYSDNYGGSRRKSSKPDEVVFNFSGELGPMPPLRNDSTKFMQRNSFMGRAGVMGLEKAVEVLDTLGSSMTRMNPSNAYLSGVTSSRGGKVTILAFEVANTIAKGAALLQSLSEENLKFMKKDMLHSEEVKKLVSTDTTELQILAASDKREELDLFSGEVIRFGNMCKDLQWHNLDRYFMKLDTENSQHKLLKDDAEARMQELVTLARITSELYHELQALDRFEQDYRRKLAEVESLNLPRRGEGIVILQNELKQQKKLVKSLQKKSLWSQNLAEIIEKLVDVVSYIRQTIVEVFGNNGLRDNEGEQGRERLGEAGLSLHYANLIQQIDNIASRPSSLPSNVRDTLYNALPATVKTALRPRLQTLDQEEELSVPEIKAEMEKSLQWLVPFAENTTKAHQGFGWVGEWANSRIEFGKGKGKGENNGNPTRLQTLHHADKPIVDSYVLELVVWLHRLMKSSKKRAHGVKLQETNHVSPPNNRTISNTQLSLSPDFTYKNQLSLEDRLLLDRVQSIRFGPNLSKSQELVGLKKNKKGFKIWALSRSTGNSPKVDLSDKNSSSDLDVLDGLDFAFQ
Protein: Collagen alpha-1(XXVII) chain (Q8IZC6)
Organism: Homo sapiens (Human)
Function: Plays a role during the calcification of cartilage and the transition of cartilage to bone.
Subcellular location: Secreted, extracellular space, extracellular matrix. Note=Found on some small banded collagen fibrils and meshworks. {ECO:0000250}.
Interaction partners:
- Laminin subunit gamma-1
- Collagen alpha-1
- Collagen alpha-2
- Collagen alpha-1
- Serpin H1
- Prolyl 3-hydroxylase 1
- Collagen alpha-1
- Collagen alpha-1
- Collagen alpha-3
- Collagen alpha-3
Sequence:
MGAGSARGARGTAAAAAARGGGFLFSWILVSFACHLASTQGAPEDVDILQRLGLSWTKAGSPAPPGVIPFQSGFIFTQRARLQAPTGTVIPAALGTELALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGKTVVHLGSRRSVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVPVLLPFHRDPALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQSDLALLGLENLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGAAFQTWMDTSGALRPESYSYPDRLVLDQGGEIFKTLHYLSNLIQSIKTPLGTKENPARVCRDLMDCEQKMVDGTYWVDPNLGCSSDTIEVSCNFTHGGQTCLKPITASKVEFAISRVQMNFLHLLSSEVTQHITIHCLNMTVWQEGTGQTPAKQAVRFRAWNGQIFEAGGQFRPEVSMDGCKVQDGRWHQTLFTFRTQDPQQLPIISVDNLPPASSGKQYRLEVGPACFL
Protein: Androgen receptor (A4GT83)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- E3 ubiquitin-protein ligase Mdm2
- Lysine-specific histone demethylase
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase
- Nuclear receptor coactivator 2
- Catenin beta-1
- peptidylprolyl isomerase
- Prostaglandin E synthase 3
Sequence:
MEVPVGLVEACESPDAVFHGPYQSVFQNVRVARASNPESLDISSSKKCGCLQEGSSREMRLSELSSFRRIICCPEKEYESASSVIQAAASRIHFLKSSSGSKSDSSLSSSGSGRTDATESSGSRAGFLRVVESGQKGCGAVEVHTRELGSGRDASVASSSRACTTATITSSSSSSSTTTSCTISETARELCKAVSVSLGLAMESSELGEVGQHHAPPPPPLTTESSEEIYLYGMPLLDCSVSEREAGRKDREYALAAGRDRGEELRGRDKVLGMLKSGDLEQLAGEVTTLQCSNASRANLTADVHEFGSLSGDIANLSSEGTAAQTAPDMDGPRAASCQFEQLLPASMTHYAHPELENGPSHSFVKSTSMSGEFAGPMEDYTNLYNVRIKTEMMPRDLNDTWAYPHRYAEDSNGHYGPPKQRTPYATGHEPPFICNPYEYGRSTALVPRERPPHEQWYPGGMLTRHPYPNVPGVKNEMGEWMDVTSFTDGRFDGGRSDIFPMEFFLPPQRTCLICSDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKLRRKNCPSCRLKKCFEVGMTLGARKLRKIGQMKGPDEVGAVQGPSETVQCLSPKPNLTFHSQLIFLNILEAIEPEVVNAGHDHGQPDSAAALLTSLNELGERQLVKVVKWAKGLPGFRNLHVDDQMTVIQHTWMGVMVFALGWRSYKNANARMLYFAPDLVFNDRRMHVSSMYEHCVQMKHLSQEFVLLQVTQEEFLCMKALLLFSVIPVEGLKSQKYFDELRLTYINELDRLINYGRKTNCAMRFQQLTRLMDSLQPVVQKLHQFTFDLFVQARSLPTKVSFPEMIAEIISVQVPKMLAGLSKPILFHK
Protein: ATP-dependent DNA helicase Q-like SIM (EC 5.6.2.4) (DNA 3'-5' helicase RecQSIM) (RecQ-like protein SIM) (AtRecQsim) (Similar to RecQ protein) (Q9FT69)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant specific 3'-5' DNA helicase that may play a role in the repair of DNA.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Exonuclease 1
- AT5G19950 protein
- DNA repair endonuclease UVH1
- DNA mismatch repair protein MLH1
- Serine/threonine-protein kinase ATR
- Exonuclease 1
- ATP-dependent DNA helicase 2 subunit KU70
- DNA mismatch repair protein MSH7
- DNA replication ATP-dependent helicase/nuclease JHS1
- DNA mismatch repair protein MSH3
Sequence:
MDLSSDQLVMKIVEMGFEKLDALEAVKAVGGKSCDDAVEYILKGNHRTGGFKPASLLCSSGSNKILGKRAMPSSFSSSESKRQSSLLDHFRSVNQNKKKGDTFGTVEVDSQLETVSEHSEEVRKSLAPVFMESSCFPEGQLLNGCSEASSSWEKRVNSILRNRFGISSLRSFQREALSTWVAHKDCLVLAATGSGKSLCFQIPALLTGKVVVVISPLISLMHDQCLKLSRHKVSACFLGSGQLDNCIEEKAMQGMYQIIYVCPETVVRLIKPLQKLAKTHGIALFAIDEAHCVSKWGHDFRPHYRKLSVLRENFCASNLEFLEYDVPIMALTATATVNVQEDILESLHLSKETKIVLTSFFRPNLQFSVKHSRTKFASSYAKDFQNLVDLYSEKKNSTGKKLAVISRESEEQTDFGSHDSENIHETDYDEDEEDQENSLAKKNSSNGKELSEAYLEDETDIFQSVDDWDVACGEFCAMPSCELLEIPVPSEKQKDLEGLTIIYVPTRKESVNIAKYLCGVGLKAAAYNASLPKKHLRQVHQDFHDNKLQVVVATIAFGMGIDKKNVRKIIHYGWLQSLEAYYQEAGRAGRDGELAECVLYADLSRAPTLLPSRRSKEQTEQAYKMLSDCFRYGMNTSQCRAKILVEYFGEEFSSKKCNSCDVCTEGPPELVDVREEANLLFQVITAFHLQVDNDSEHAPYEDYGLGNSKQNKLSHKPNLLFFISKLREQCEKFKETDCLWWKGLARIMEAEGYIKEMDNKDRRVEIKFIQPTEKGKKQLDFQDDKPLYVYPEADMLLSLKQDRTYSGFSEWGKGWADPEIRRQRLERRERKPRRERKPRKKRTRGRSSTKLHPWRSKE
Protein: Pentatricopeptide repeat-containing protein At4g35850, mitochondrial (Q8VYR5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14671022, ECO:0000305|PubMed:25732537}.
Interaction partners:
- Afadin/alpha-actinin-binding protein
- Selenoprotein O
- F21B7.34
- At2g17975
- Pentatricopeptide repeat-containing protein At1g80270
- Omega-amidase, chloroplastic
- Pentatricopeptide repeat-containing protein At1g26460
- Pentatricopeptide repeat-containing protein At1g02150
- Protein PEP-RELATED DEVELOPMENT ARRESTED 1, chloroplastic
- GrpE protein homolog 2
Sequence:
MKFLMQSISGRNRSLVRALVSRRYFASSPEEIAKRNYANDLSEYNTAVNSVTAQRRHYLLRDVYDDMKLDGVQPTADIFHSFVVGTMKGARLSDAFFFREEMKAMGIAPDVNLYNFLISTCGKCKNGKEAIRVYDEMKRYDVKPNGQTFVCLLNACAVSGQLDLVYAIVRDMTAAGVGLNQFCYAGLITAHLNKQPRPDNLSTKILEFVEQSKGWSAIDSSRKSAEDVMFSISEEELYNIPTADYSHRTRFLQRNLTVYHVAFSALADLKDVKATEALLEMLKKDGKDTDTYCMLQIMRCYLHSQDFENGLKLFQDYMSADKIPAMELYTTLIEGAMTGYTDNGMKIAQDTLIQMNERNFFLDPRTGSNLLLKAAGEKTGGYTVANMIWDLMLARNILPTLAAVEAYYKGLKEREIPEDDPRLMLVTRTYNNLRLREGTLPNRR
Protein: pectate lyase (EC 4.2.2.2) (Q7C4I5)
Organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Type III helper protein HopAK1
- pectin lyase
- Conserved domain protein
Sequence:
MSIGITPRPQQTTTPLDFSALSGKSPQPNTFGEQNTQQAIDPSALLFGSDTQKDVNFGTPDSTVQNPQDASKPNDSQSNIAKLISALIMSLLQMLTNSNKKQDTNQEQPDSQAPFQNNGGLGTPSADSGGGGTPDATGGGGGDTPSATGGGGGDTPTATGGGGSGGGGTPTATGGGSGGTPTATGGGEGGVTPQITPQLANPNRTSGTGSVSDTAGSTEQAGKINVVKDTIKVGAGEVFDGHGATFTADKSMGNGDQGENQKPMFELAEGATLKNVNLGENEVDGIHVKAKNAQEVTIDNVHAQNVGEDLITVKGEGGAAVTNLNIKNSSAKGADDKVVQLNANTHLKIDNFKADDFGTMVRTNGGKQFDDMSIELNGIEANHGKFALVKSDSDDLKLATGNIAMTDVKHAYDKTQASTQHTEL
Protein: Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Aldolase 1) (Muscle-type aldolase) (P05064)
Organism: Mus musculus (Mouse)
Function: Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (By similarity). In addition, may also function as scaffolding protein (By similarity).
Subcellular location: Cytoplasm, myofibril, sarcomere, I band {ECO:0000250|UniProtKB:P00883}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:P00883}. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+). {ECO:0000250|UniProtKB:P00883}.
Interaction partners:
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Pyruvate kinase PKM
- ATP-dependent 6-phosphofructokinase, liver type
- Glucose-6-phosphate isomerase
- ATP-dependent 6-phosphofructokinase, platelet type
- ATP-dependent 6-phosphofructokinase, muscle type
- Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
- Phosphoglycerate mutase 1
- Transaldolase
Sequence:
MPHPYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY
Protein: Serine/threonine-protein kinase ppk16 (EC 2.7.11.1) (Meiotically up-regulated gene 92 protein) (Q9URY1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Note=Located at the cell tips and the septum.
Interaction partners:
- 5'-AMP-activated protein kinase subunit beta
- 5'-AMP-activated protein kinase subunit gamma
- Translationally-controlled tumor protein homolog
Sequence:
MKKNEKANISASYNDLIATICNPRISDVGTYRIESVVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAIILAREIHHHRRLLHPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTFMNTRCGTVAYCAPELVQGHKYIGECVDIWSLGIIMYALLIGRLPFDEDDVSLTEQKIINECPQYPETLSKNSSSLLKSLLCKDYRLRPSIDQIISHPYFKENGYHSSSIRDPRPSSKAEEKVRKRLEFVGVDMDQLNASISQQRCDMFYGWWLLLLEKEMRKENKKKKGLFHLHKGSSSAVHIAPATPSLKTAQVSVMSNNQDSLKSRHTSSDSSNSLLSTFRSWLFDPKQKHTADTLSSSAIRPRTPSPSAENYLTQENFDSDNLSESLDNSVENLTVFPSINSFGRRHSNLPQTTHVDTGEQNTPFTPPLLKTVNLDGNKDFTFPSNSQNSPSKSSNLSINIDIPPSPLQNTVISPQPTRRSRTPIRSLSGRSSVASSRNSSRTRSYSNVSSASSNSLISIISSKPSSSTVQRQTPFHSPFERLHKSFHFPSGEPFNTRINATAIFTVGSGRKNPQSSSSLMFNQSSVKEEEEPEETSFSDSSKHFTDLL
Protein: NADPH oxidase, isoform B (EC 1.6.3.-) (A0A0B4LFI7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MNADQESNNHRGSVSSSRSLEIPATPSRSPKKVSFSDELPQSQTPAQQPINQQSAPTVVSHVLQQAAQYLERLHGARDSAEEKTEEVQPERADIRDSSDTSEAAVLDLDALDASADEPAANAGPIVASSPSILIGSVNRQEAIGSANGNGNANPNQRQSNLYMERYNLNLDKNCSSMELEARREKQRWLLISECSALFDEGEGKHTREAFRKLFLDEEFQQKLFQLFDLERNGYLLQDRWIEHLKGRLTDDRQMDFAEQIESVAYVICGENKRVSFKNFRDIWHTRGILDKLYRLIELDGSNLVSTNQVMEFISHLTNSRPRTGFDKSSLARLEQLFRTTVGNEQEIRREEFQKIVTSKNPFFTERVFQIFDKDNSGSISLQEFIDAIHQFSGQSADDKIRFLFKVYDIDGDGLIQHKELHDVIRHCIKENGMEFSEDQIEDLTSAMFEDADPHNSGEITYEALKNQLHKHGGLLENLSITIDRWLVPIAEDRQAGGAAKSGFWNSLPHQFSLAYMKNNQVFVTYLFFYITVNLCLFISRAIQYRASNGFVIIARACGQCLNFNCAWVLVLMLRHSLTYLRGRGLSSYLPLDHHVYLHKLTGITISVLSLIHTIMHLFNFSIIVINDPNINAGHYTIGEWLLTDRPGLFGLIPGCANPTGVALLAILVVMFVCSQPFVRRKGSFEVFYWTHLLYVPFWILCLFHGPNFWKWFLLPGLVYIVERALRFIWMRGEHGKTYISSGLLLPSKVVHLVIKRPHHFNFRPGDYVFVNIPAIANYEWHPFTISSAPEQEDYMWLHIRTVGEWTNRLYRYFEREQQKLQQSGSSQEIPQHMHAIPTPSFMLLNEARNPAIAGERSATPQTDFLAKNLGVQAVPPVRPPRQNRKPAPGAPIDPPATGVNRIRSIKKTLQRTFSRKEAVDPKKGIPNGAFIADGEREDSNLKQRPLEKSISLPDISVKSKKRSRLKALRALGRSESESAFDEKRVRRARNNSVGLAYLSPQNKSLAQSFRYMRTKPTIIAFKTPSMEEREHQVAAGEANGASPASRAEQGQLSSRMDSADKLQLARLSLSAEGASKPLEIFIDGPYGAPSSHIFGAQHAVLIGTGIGVTPFASILQSIMHRYWKARHSCPRCQFEWASEIPKSVMNLRKVDFFWINRDQRSFEWFVNLLSQLEIEQAELGGAMERFLDMHMYITSALQRTDMKAVGLQLALDLLHEKGKRDLITGLKTRTNAGRPNWDKVFKQLQAQQKGKVTVFYCGPPQLAKTLRYKCDQYGFAFRKECF
Protein: Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (E9PQ56)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MATATIALVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA
Protein: Large ribosomal subunit protein uL1 (60S ribosomal protein L10a) (Q6PC69)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62906}.
Interaction partners:
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- FAU ubiquitin-like and ribosomal protein S30 fusion b
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein eL20
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL29
- Ribosomal protein L26
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein eS4
Sequence:
MSKVSRDTLYEAVKEVQAGSRRKKRKFLETVELQISLKNYDPQKDKRFSGTVRLKTTPRPKFSVCVLGDQQHCDEAKAAELPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLGTKVDEVKSTIKFQMKKVLCLAVAVGHVKMSEEELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY
Protein: Small ribosomal subunit protein bS21m (37S ribosomal protein MRP21, mitochondrial) (P38175)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS8m
- Small ribosomal subunit protein mS23
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein bS1m
Sequence:
MLKSTLRLSRISLRRGFTTIDCLRQQNSDIDKIILNPIKLAQGSNSDRGQTSKSKTDNADILSMEIPVDMMQSAGRINKRELLSEAEIARSSVENAQMRFNSGKSIIVNKNNPAESFKRLNRIMFENNIPGDKRSQRFYMKPGKVAELKRSQRHRKEFMMGFKRLIEIVKDAKRKGY
Protein: Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1) (Q8NHQ8)
Organism: Homo sapiens (Human)
Interaction partners:
- Apoptosis-stimulating of p53 protein 2
- Fibulin-1
- Apoptosis-stimulating of p53 protein 1
- FERM domain-containing protein 6
- Partitioning defective 3 homolog
Sequence:
MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV
Protein: IP11374p (TWIK-related acid-sensitive K[+] channel 7) (Q9VHE0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Acid-sensitive two pore domain K+ channel dTASK-6
- HDC12658
- BcDNA.GH04802
Sequence:
MMKRQNVRTLSLVVCTFTYLLIGAAVFDSLESPTEAKRWEFLQTVKNNFVRKYNVTDEDFRVMEIVIIENKPHKAGPQWKFAGAFYFSTVVLAMIGYGHSTPVTIPGKAFCMGYAMVGIPLGLVMFQSIGERLNKFASVIIRRAKRASGARCTDATEMNLMLATGMLSSIIITTGAAVFSRYEGWSYFDSFYYCFVTLTTIGFGDYVALQNDQALTNKPGYVALSLVFILFGLAVVAASINLLVLRFMTMQAEDAKRDEQDAQNLAGNAQPVTFDDESTYNMHGKLLENNYTTENDETASLCSCTCMGGTRCLNHEQFVDPDFQPTDIIESTLCLKRASV
Protein: Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase) (P14324)
Organism: Homo sapiens (Human)
Function: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
Subcellular location: Cytoplasm.
Interaction partners:
- Hydroxymethylglutaryl-CoA synthase, cytoplasmic
- Geranylgeranyl pyrophosphate synthase
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- Squalene synthase
- Diphosphomevalonate decarboxylase
- Isopentenyl-diphosphate Delta-isomerase 1
- Isopentenyl-diphosphate delta-isomerase 2
- Hydroxymethylglutaryl-CoA synthase, mitochondrial
- All trans-polyprenyl-diphosphate synthase PDSS1
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Sequence:
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK