wanglab/gogpt-training-data huggingface dataset:
Protein: Conjugal transfer protein (ORF13-like protein) (Q1PLH8)
Organism: Clostridium perfringens
Interaction partners:
Sequence:
MFRKNKENTKPKKEKKEKKSFFKKKDKLNMDLEDSVANLDKQVNGVKEKKLVSVMPFRIARAFIWVLIGILCFRGGVSVFKGNQSEALKKENEKILNNMEKQSSLETQAFSFAEEFAWDYFSRYPSDTQDFVRRITKYTTEQLANEMNNGTYSDVIYTSAFYFEKYSENQVNVSVKARVRVYTPKAGQEQTPQDQLQYDTNLVDYYLEVPIVFDKDMNMAVDALPVMTAPPEKAYFKNKEFSGTSENDADKTKKITDSVSQFFKAYYEQNQTQIDYFLVDGADIKGAGQKFSFNKIDRINIYKLSDKEFLAIVDLNVDSFGNAIKQGFNLTVVQEGDKFLVKTLEPRTSNIDLNNKSNN
Protein: Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor) (P35368)
Organism: Homo sapiens (Human)
Function: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
Subcellular location: Nucleus membrane; Multi-pass membrane protein. Cell membrane {ECO:0000269|PubMed:24567387}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:24567387}. Membrane, caveola {ECO:0000269|PubMed:24567387}. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.
Interaction partners:
- Guanine nucleotide-binding protein G
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Guanine nucleotide-binding protein subunit alpha-11
- Guanine nucleotide-binding protein subunit alpha-12
- Guanine nucleotide-binding protein subunit alpha-13
- Thromboxane A2 receptor
- Angiotensinogen
- Inositol polyphosphate 1-phosphatase
- Guanine nucleotide-binding protein subunit alpha-15
Sequence:
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
Protein: Uncharacterized protein, isoform A (Uncharacterized protein, isoform B) (Q9VIN6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MIKCIWLLFSTLYIQDTGASDKWCKADLCRGQHVLCDDNGNFESTCPKQAAAMVKMSWDMIALIVDKHNEYRNKFAGGMDQNPKAARMTTIEWDPELAKVADGLVRRCEPIRDQCAITPNYGHAEVSYSLEKYFCMTTKKEALRKQLDHWFDPNSKDEVQKLFFSWTKNQQELSKNYFQVLRDRANRVGCAIVEYVRPALVHQLLKCVYNCGVSLCEEEDNPVYEDTDEEAASECMKGSNKQYKNLCHKDELVKTCNGGSLFVEPENDYNDGQEENMENDYEFETTVFTLPTYDPNDVLPTLPDNPDLNFNTIVKD
Protein: Paired box protein Pax-7 (P47239)
Organism: Mus musculus (Mouse)
Function: Transcription factor that is involved in the regulation of muscle stem cells proliferation, playing a role in myogenesis and muscle regeneration.
Subcellular location: Nucleus {ECO:0000269|PubMed:22862948, ECO:0000269|PubMed:34059674}.
Interaction partners:
- Myoblast determination protein 1
- Myogenin
- Paired box protein Pax-3
- Myogenic factor 5
- Myogenic factor 6
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Forkhead box protein O1
- Dystrophin
- Cadherin-15
- Myosin-1
Sequence:
MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEDDEEGDKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGYSVDPVAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY
Protein: Single stranded DNA-binding protein 3a (Single-stranded DNA-binding protein 3a isoform X1) (A0A2R8QDI9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFAKGKGTAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRDTCDHSSEAKAFHDYSAAAAPSPVLGNLPPGDGMPGGPIPPGFFQQGPPGSQPSPHAQLPPNANMMAAHGQPFMSPRYAGGPRPPMRMGNPPPGGQPLPPNMMDPTRPTGHPNLASMQRMNAPRGMGPMGPGPQSDPWLSLQNYGGGMRPPNSMGPGMPGVNMVAGAGRPWPNPNNGNTISYSSSSPGTYVGPPGGAGGGGCPPGTPIMPSPADSTNSGENLYTLINSVPPGGNRSSFTMGPGSDGPMGGLEPHHMNGSLGSGDIDGLTKNSPNNLSGLSNPPGTPRDDAELSGSFLHSFQNENYSPTMTMSV
Protein: Lipoprotein LpqN (O53780)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in cell envelope biogenesis. May act as a membrane fusion protein, connecting MmpL transporters with periplasmic proteins, and play a role in cell envelope lipid changes during biofilm maturation.
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}. Secreted {ECO:0000269|PubMed:30118682}.
Interaction partners:
- Probable conserved lipoprotein LppZ
- Putative diacylated glycolipid transporter LprF
- Putative phthiocerol dimycocerosate transporter LppX
- Uncharacterized glycosidase Rv0584
- Lipoprotein LprA
- Probable lipoprotein aminopeptidase LpqL
- Lipoarabinomannan carrier protein LprG
Sequence:
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
Protein: Phenoloxidase subunit 1 (EC 1.14.18.1) (proPO-P1) (O44249)
Organism: Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
Function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone. Binds to the surface of hemocytes and is involved in hemocyte melanization.
Subcellular location: Secreted {ECO:0000269|PubMed:9474780}.
Interaction partners:
Sequence:
MTDAKNNLLYFFDRPNEPCFMQKGEDKVVFEIPDHYYPDKYKSLSNTLSNRFGNEATKRIPIRNITLPNLEVPMQLPYNDQFSLFVPKHRTMAAKLIDIFMGMRDVEDLQSVCSYCQLRINPYMFNYCLSVAILHRPDTKGLSIPTFAETFPDKFMDSKVFLRAREVSNVVISGSRMPVNVPINYTANTTEPEQRVAYFREDIGINLHHWHWHLVYPFDSADRSIVNKDRRGELFYYMHQQIIGRYNVERMCNGLPQVKPFSDFSAPIEEGYFPKLDSQVASRTWPPRFAGSVFRNLDRTVDQVKIDVRKLFTWRDQFLEAIQKMAIKMPNGRELPLDEVTGIDMLGNLMESSIISPNRGYYGDLHNMGHVFAAYTHDPDHRHLEQFGVMGDSATAMRDPFFYRWHRFVDDVFNIYKEKLTPYTNERLDFPGVRVSSVGIEGARPNTLRTLWQQSTVELGRGLDFTPRGSVLARFTHLQHDEFQYVIEVNNTTGGNLMGTVRIFMAPKVDDNGQPMSFNKQRRLMIELDKFSQALRPGTNTIRRRSVDSSVTIPYERTFRNQSERPGDPGTAGAAEFDFCGCGWPHHMLIPKGTAQGYPVVLFVMISNWNNDRIEQDLVGSCNDAASYCGIRDRKYPDKQAMGYPFDRKMANDAATLSDFLRPNMAVRDCSIQFSDTTVERGQQG
Protein: E3 ubiquitin-protein ligase ATL31 (EC 2.3.2.27) (Protein CARBON/NITROGEN INSENSITIVE 1) (Protein SUPER SURVIVAL 1) (RING-H2 finger protein ATL31) (RING-type E3 ubiquitin transferase ATL31) (Q8LGA5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase that is required for the plant C/N response during seedling growth transition. May be involved in the early steps of the plant defense signaling pathway.
Subcellular location: Membrane {ECO:0000269|PubMed:19702666}; Single-pass membrane protein {ECO:0000269|PubMed:19702666}.
Interaction partners:
- Syntaxin-121
- Acyl-CoA N-acyltransferases
- Transmembrane protein
- Calcineurin B-like protein 8
- Probable WRKY transcription factor 33
Sequence:
MDPIKHISLPVLVLFLLLSVSAGQPGTPDQRHDPYAYSGSLSPAMAVVVVVVIAALFFMGFFTVYIRHCTGAVDGSVTPAGGARRRVTNATVARGLDAETIETFPTFVYSEVKTQKIGKGALECAICLNEFEDDETLRLLPKCDHVFHPHCIGAWLQGHVTCPVCRTNLAEQTPEPEVVVETDLEAQQQSAVPVPVVELPRVKFPRSHTTGHSVVLPGESTDRFTLRVPEELRKKIMANWKLNRSNSVFVLPRGGSSRSGKQVDRSRAKSDRWLFRKTPSFLWRNRDDGSIRLGGTGSVRGNSVTSPSGDSVRADRWAFLRNPSFLWRNTTPVPSPRVEVNNKDGEGTSSVQHIGTVGSTSGSLRLPV
Protein: Serpin H1 (Collagen-binding protein) (Q9Z1W7)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Interaction partners:
Sequence:
MRSLLLGSFCLLAVALAAEVKKPVEAAAPGTAEKLSSKATTLAERSTGLAFSLYQAMAKDQAVENILLSPLVVASSLGLVSLGGKATTASQAKAVLSAEKLRDEEVHKGLGELLRSLSNSTARNVTWKLGSRLYGPSSVNFVEDFVHSSKQHYNCEHSKINFRDKRSALQSINEWASQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQILEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKAWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDNQSGSLLFIGRLVRPKGDKMRDEL
Protein: Protein SOSEKI 4 (PpSOK4) (A9RNY0)
Organism: Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens)
Function: SOSEKI proteins locally interpret global polarity cues and can influence cell division orientation to coordinate cell polarization relative to body axes.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9SYJ8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9SYJ8}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9SYJ8}.
Interaction partners:
Sequence:
MPSLRTERRSFGMETPRHSSFRMAEVLYVLSCGGQLEHPHMINVQYPVHQPGPTLRDVKTRLIALRGRGMPDSFSWSYKRNYKDTFIWCDLFDDNFILPLSESGEYALKATKRFDASQVKYLRPPRRSENLEAEGDVSMVVKKGLVLISDTGSVTSNRTMELNKQLMNSLSHSRSAAAVRNNEHSDVSSSDTHYSYEDVIERKDYPARCKSNSGATKRGKASVTPKQCHPSSRPAYWEFSPQGNRTGREDSLMTIGLTKHVVEENEGPTTPRAPARRRTWKKEIDKITIFRESNNSESSDDEQPSVQAETHVSKLSKSGGSYSAAPEDLFLYILRKATRLGSFKPRVCTEVDVVDSTQSKTKMLFRSKTKDEVNRLLYHSPLKQDQSIKK
Protein: Protein cft1 (Cleavage factor two protein 1) (O74733)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- mRNA 3'-end-processing protein yth1
- mRNA cleavage and polyadenylation specificity factor complex subunit pta1
- Pre-mRNA polyadenylation factor fip1
- Poly
- Cleavage factor two protein 2
- Endoribonuclease ysh1
- Polyadenylation factor subunit 2
- RNA polymerase II subunit A C-terminal domain phosphatase ssu72
- Uncharacterized RING finger protein P8B7.15c
- Uncharacterized WD repeat-containing protein C824.04
Sequence:
MSTIFQDLVDSTVIKNAVQGQFTSLVSNNLVVSKVNSLHLFEIEKIQKDESSFPLDDSLQNEFSTSIIDESQAFMETNMHLIRTNEQTTYVLRLVSQVKVFGTITEISALKGKGSNGCDLLIMLTDYAKVSTLEWDMQSQSFVTNSLHYYEDVKSSNICSSHTPTQLLVDPDSDCCLLRFLTDMMAIIPYPANEDLDMEEAAIENSKISSSYAYKPSFVLASSQLDASISRILDVKFLYGYREPTLAILYSPEQTSTVTLPLRKDTVLFSLVTLDLEQRASAVITTIQSLPYDIYASVSIPTPLGGSLLLGGNELIYVDSAGRTVGIGVNSYYSKCTDFPLQDQSDFNLELEGTIAIPLTSSKTETPFVVLVHTSGQFFYLDFLLDGKSVKGLSLQALDLEINDDFLKSGITCAVPAGENLVFLGSQTTDSYLLRWSRRTTNEEVRLDEGDDTLYGTNDAEMDDMLDIYETDESVGSKRKIAYENGPLRLEICDVLTNIGPITDFAVGKAGSYSYFPQDNHGPLELVGTAGADGAGGLVVFRRNIFPLIAGEFQFDGCEALWTVSISGKLRNMKSRIQAQYSNPELETYLVLSKEKESFIFLAGETFDEVQHSDFSKDSKTLNVGSLLSGMRMVQICPTSLRVYDSNLRLTQLFNFSKKQIVVSTSICDPCIIVVFLGGGIALYKMDLKSQRLIKTDLQNRLSDVKTASLVSPDSSALFAKLFTYNETLNAKGQIANGMNDSASETDLDIQPNHKTSNNDQMGYDQSVSADDVPEVDNTIVTEKNVSNLDQESLEKHPILFALTDEGKLKVYNLADFSLLMECDVFDLPPTLFNGMESERTYFNKESSQELVELLVADLGDDFKEPHLFLRSRLNEITVYKAFLYSNTDKHKNLLAFAKVPQETMTREFQANVGTPRDAESTMEKKASSSVDHLKMTALEVVGNHSAVFVTGRKPFLILSTLHSNAKFFPISSNIPILSVAPFHAHHAPQGYIYVDENSFIRICKFQEDFEYDNKWPYKKVSLGKQINGIAYHPTKMVYAVGSAVPIEFKVTDEDGNEPYAITDDNDYLPMANTGSLDLVSPLTWTVIDSYEFQQFEIPLSVALVNLEVSETTKLRKPYIAVGTSITKGEDIAVRGSTYLFEIIDVVPQPGRPETRHKLKLVTREEIKGTVAVVCEVDGYLLSGQGQKVIVRALEDEDHLVGVSFIDLGSYTLSAKCLRNLLLFGDVRQNVTFVGFAEEPYRMTLFSKGQEALNVSAADFLVQGENLYFVVADTSGNLRLLAYDPENPESHSGERLVTRGDFHIGNVITAMTILPKEKKHQNAEYGYDTGDDFSCVMVNSDGGLQMLVPISDRVYRRLNIIQNYLANRVNTIGGLNPKSYRLITSPSNLTNPTRRILDGMLIDYFTYMSVAHRHEMAHKCGVPVSTIMNDLVELDEALSYM
Protein: NAD-dependent protein deacetylase (EC 2.3.1.286) (C6ZII9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Forkhead box O3
- NAD-dependent protein lipoamidase sirtuin-4, mitochondrial
- NAD-dependent protein deacylase sirtuin-5, mitochondrial
- Nicotinamide phosphoribosyltransferase
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
- Acetyl-coenzyme A synthetase
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- Sirtuin 6 6
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- NAD-dependent protein deacetylase sirtuin-7
Sequence:
MALSCRLVLAALRLWGPGGGRRPISLSVGASGGFGCGGHSEKKLSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFTLAKELYPGHYRPNVAHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGSFVSATCTVCRRSFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEQLPARFLLHVADFALADLLLILGTSLEVEPFASLSESVQKSVPRLLINRDLVGSFALSPRRKDVVQLGDVVQGVERLVDLLGWTQELQDLIQRENGKLDGQDG
Protein: Naglu (EC 3.2.1.50) (O54752)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MEAAGLAVILGFLLLAGGSVGDEAREAKAVRELVVRLLGPGPAANFLVSVERALADESGLDTYSLSGGGGVPVLVRGSTGVAAAAGLHRYLRDFCGCQVAWSSAQLHLPWPLPAVPDGLTETTPNRYRYYQNVCTHSYSFVWWDWARWEQEIDWMALNGINLALAWNGQEAIWQRVYLALGLTQSEIDTYFTGPAFLAWGRMGNLHTWDGPLPRSWHLSQVYLQHRILDRMRSFGMIPVLPAFAGHVPKAITRVFPQVNVIKLGSWGHFNCSYSCSFLLAPGDPMFPLIGNLFLRELTKEFGTDHIYGADTFNEMQPPFSEPSYLAATTAAVYEAMVTVDPDAVWLLQGWLFQHQPQFWGPSQIRAVLEAVPRGRLLVLDLFAESHPVYMHTASFHGQPFIWCMLHNFGGNHGLFGALEDVNRGPQAARLFPNSTMVGTGIAPEGIGQNEVVYALMAELGWRKDPVPDLMAWVSSFAIRRYGVSQPDAVAAWKLLLRSVYNCSGEACSGHNRSPLVKRPSLQMSTAVWYNRSDVFEAWRLLLTAAPNLTTSPAFRYDLLDVTRQAVQELVSLCYEEARTAYLKQELDLLLRAGGLLVYKLLPTLDELLASSSHFLLGTWLDQARKAAVSEAEAQFYEQNSRYQITLWGPEGNILDYANKQLAGLVADYYQPRWCLFLGTLAHSLARGVPFQQHEFEKNVFPLEQAFVYNKKRYPSQPRGDTVDLSKKIFLKYHPQPDSL
Protein: Conserved protein (O05848)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Transcriptional regulator WhiB1
- Probable conserved integral membrane protein
Sequence:
MRAVLIVNPTATATTPAGRDLLAHALESRLQLTVEHTNHRGHGTELGQAAVADGVDLVVVHGGDGTVSAVVNGMLGRPGTTPVRPVPAVAVVPGGSANVLARALGISADPIAATNQLIQLLDDYGRHQQWRRIGLIDCGERWAVFNAGMGVDAEVVAAVEAERDKGGKVTAWRYIRAAVRAVLACTRREPALTLQLPNRDPITGVHFVFVSNSSPWTYANNRPVWTNPDCRFESGLGVFATTSMKVVPTLRVVRQMFAKQPKFEFNHVINNDDVACLRVTSMGPPIASQFDGDYLGVRETMTFRAVPDALAVVAPPARKRI
Protein: AT3g08600/F17O14_7 (Transmembrane protein, putative (DUF1191)) (Q9C9Z6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGFLRCLQLLLLLFLSLRLQKLSAQSSSPNASSSSSLDALLQDYSFRALLRPRTGILYEATTVPSNLTGIKLAAMRLRSGSFRKRGVTPFNEFSIPSGVIVKPYVTRLVLVYQNLANFSHLYYPLSGYDYVAPVLGLLAYDAKNLSALNLPQLDLRVSNDPIRIDFSDLERIPQGSSAKCVRFDSKGEASFSDSIQPGNTCETEHQGHFSVVVKSVASAPSLAPPGIESKKKKKSSDSNSKTWIIVGSVVGGLILLGLLLFLVLRCRNYKKQEKMREMERAGETGEALRMTQVGETRAPTATTTRTQPMLETEYAA
Protein: Mitogen-activated protein kinase 17 (AtMPK17) (MAP kinase 17) (EC 2.7.11.24) (Q84M93)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Mitogen-activated protein kinase kinase 1
- Uncharacterized protein
- Peroxisomal and mitochondrial division factor 1
- Protein-tyrosine-phosphatase PTP1
- Mitogen-activated protein kinase kinase 10
- Mitogen-activated protein kinase kinase 9
- Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein
Sequence:
MLEKEFFTEYGEASQYQIQEVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHPDIVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKVNDDLTPQHHQFFLYQLLRGLKFMHSAHVFHRDLKPKNILANADCKIKICDLGLARVSFTDSPSAVFWTDYVATRWYRAPELCGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPITLSRIRNEKARKYLGNMRRKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALADPYFQGLANVDYEPSRQPISKLEFEFERRKLTRDDVRELMYREILEYHPQMLQEYLQGEENINSHFLYPSGVDQFKQEFARLEEHNDDEEEHNSPPHQRKYTSLPRERVCSSEDEGSDSVHAQSSSASVVFTPPQTPNTATGLSSQKASQVDKAATPVKRSACLMRSDSICASRCVGVSSAVS
Protein: C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)] (O00626)
Organism: Homo sapiens (Human)
Function: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
Subcellular location: Secreted.
Interaction partners:
- C-C chemokine receptor type 4
- C-C chemokine receptor type 8
- Platelet factor 4 variant
- C-C chemokine receptor type 3
- C-C motif chemokine 14
- C-C chemokine receptor type 2
- C-C chemokine receptor type 7
- Atypical chemokine receptor 2
- C-X-C chemokine receptor type 4
- C-C chemokine receptor type 5
Sequence:
MDRLQTALLVVLVLLAVALQATEAGPYGANMEDSVCCRDYVRYRLPLRVVKHFYWTSDSCPRPGVVLLTFRDKEICADPRVPWVKMILNKLSQ
Protein: Zinc finger, MYND-type containing 8 (A0A8I5XZV4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSTERTAQKRKVPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSSKDQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPVNNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRKKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKIILSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKPDKTSTATTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEDPEDKEGSRVDKEAPAIKRKPKPSNQVEVKEEVKSNSPVGEKVDPAPAKDKASPEPEKDFAEKAKPSPHPTKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKPPPPTPAGNQSPPETPVLTRSATQAPAAGVTVAATTSTMSTVTVTAPATAAVTGSPVKKQRPLLPKETVPAVQRVVWNASSKFQTSSQKWHMQKIQRQQQQQQQQQQQQQSQQQQPQSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASVINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEANQETGNKTSQGSSSNTQSAPSEPASTPKEKETSSSSSNSSSTEKSKDSNSTLDLSGSRETPSSILLGSNQGSVSKRYDKQPAYTPTTTDHQPHPNYPAQKYHSRSSKAGLWSSSEEKRGSSRSEHSAGTSTKNLMPKESRESRLDTFWD
Protein: No long nerve cord, isoform G (EC 3.4.24.-) (X2JAM1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MSVNMNWTSPKIWAALFVTTLCLLDTQAAWAKKLNASQAFDDTWNTASDLENELEQQKRSKVQSAGGGGGAGGGPGQWSSWSDWSTCSRTCDGGIMHQMRRCGSPGSCRGESTRYRICNMQPCPEQQDFRSSQCSAYNDVPYDGTLYKWTPHYDYVEPCALTCRGHPAHLVEDISRETGDGNAEEAEHYDEQSVIVQLSARVQDGTRCRSGSLDMCIQGKCQRVGCDLKIGSTKKIDGCGVCGGDGNSCSQPLFNWEMAPMSQCSVTCGSGYKMSRPICRNRLTNADVDDTLCSVTNRPEASVEQCNTHSCPPRWIADDWSTCSRLCGHGYRERMVVCAEESNGIKTRVADIMCRTPKPPTQETCIIEECPHWEVEDWTGGIQMRGVECKSTDGSLSAKCDPLTKPGSMQQCSTGIHCGGSLNKVGGTIIVGSSRSLNERSERQLDSSDADEDNEDENDEGDDVDDLESGQDTDDGEGLSYADQPLLYAHRTQSRLNQEAPDEPRTMHLMNGNSNNNFNRGEDESEGPSLDPTYIKDNEWSPCSVTCGEGIRRRTYNCKIFLEYSRTVATVNDSLCEGKKPHDEVERCVEDPCMLPSHGFDDQFPRDSIKVGVSEPGKTYVWREQGYTSCSASCLGGVEELIINCVREDNGRVVSPFLCSPETKPEARVRTCNDRPCPPRWNYSDYTPCSKSCGIGIKTREVQCIHEVTRGGDNTMVVPNSMCPQPPPADRQYCNVLDCPVRWEVGEWSKCSHTCGYGFKDRKVECKQIMAQEHKIERPESMCPSAKPADKKPCNVKPCPPEDPKPVIQINNSTHIQHDPKKTKITLKVGGAGLVFFGTQVKIKCPVKRYNRTKIKWSKDHKPLQRSRKYKVSKKGALRILDITFRDAGVYSCHAGLSSAEISIEVKAKPGQQIEELEQQETERLVREKSGTEALTSADMKSADGTGTSTAVGPNSHVNGSAQQHGSRRRQQQSERLQNGRERSRRPKSDGVQHADSSIMEDDLLWPLQRFKDSRGQHLLQGEALKFGIDLSGKDFDQDESERVPAEQLPPEVLHSPSDPEYHEPSKSGPEADVPHVPPHMPHARWETGAAASTTAVPSLPNDGFVYRWMLGEWSQCSQECGAAGSGLQRRTVSCQRAAKATSSGSTSDTENNVVDNSECFAHGLELPEFFQSCGNEACPQWSKGDWTPCQRSHCHGRNTAMQRREVTCRYPNGTEGSICDEYERPAMRQECYNERCEGVWRVEPWSECNAPCGRKGIKYRILQCVWYGSRRPAGNVCKHQPRPAVMKVCKSPACQAQLSSSPAQLCRDSSRYCRNARAMGLCRLHRYKLKCCGSCEQQPNQHLIL
Protein: Transcription elongation factor SPT5 (Chromatin elongation factor SPT5) (Q5ALX3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription elongation factor SPT4
- Transcription elongation factor SPT6
- DNA-directed RNA polymerase II subunit
- DNA-directed RNA polymerase subunit
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase subunit
- FACT complex subunit SPT16
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
Sequence:
MSDSDLPVQVKKEPSFANDDDLTFDEEFRRAGDQENKEVENPDDGRSLKRTREESEQEENNEKEQDQEAGQDEEEQDEDEEEEEDDEEEDEEDEVSSRRKRRRGANQFFDIEAEVDDEEEDEEDEDEEAELMREEFITDDHAPVETVEKMPQDDRLHRQYDNRRQQAEDQDAEQLAETLKQRYRKTHSVYRGETAASGTVSQKLLMPSINDPSIYAIRCTPGREKELVRKLYEKKRTLERQGNPLDILTVFQRDAFTGYIYIEAKRPDAIDKALVGMVNVFVRDKLLVPVKEYPDLLKQVKSSDVEIRPGIYVRIKRGIYRGDLAIVDNLSENGLDVRCQVVPRLDYGQNDEIGPDGKVIKSKIKPLPALFSEQKARMYDPYKLQMGRVPNSFIYRGNEYYDGYLYKDFKLQFIQTKDVNPTLEELDRFQNQNDEDGLNLQAIAATLKGNNAGEGKSSTAFQPGDKVEIRRGEQAKTIGIVVETALNEITIKVTDSGDPRFVDQRLTVPANDLRKIFYEGDHVRIVEGKHFDETGLVIKIDGDSVVIVSDQTKEDVRVFANYLVKATDASSNFDLLNSKYDIKDLVELSGLTVGVIIKAEKNIFDVLTTDGRLISVRQSGIASKLKQSRREQVATDRNGTTIRVGDTVKELLGEKSREGAILHIYKNALFIKSNEIVENLGIFVANRMNVTTVATKDSTVSKSLGPDLTSMNPNLRLPNPVAVAGLKTRVGGRDKLLYKDVAVTSGSYKGLKGKVTEADDLYARIELHTKSKKIKVLKNNLNVIVHGQPVPYLRFIGAAPEFSQPTPPTYGSSSGGRSAWNGGMTPSVSAGNGGVSAWGGSRGGFGGDGGKTPAYGAGGASTWGGASAWGGGAGGSSAWGGIKGAGSVWDRSKGGSSASSGNQGGNTAWDRNKGGNSTWDRSKGGSSSWESGSTWEGGNNTTWGSKKGNTSAWGRN
Protein: Kri1-like C-terminal domain-containing protein (Q57W29)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- KRR1 small subunit processome component
- Nop14-like protein
- Nucleolar complex protein 2
- Bms1-type G domain-containing protein
- U3 small nucleolar ribonucleoprotein protein MPP10, putative
- Periodic tryptophan protein 2, putative
- U3 small nuclear ribonucleoprotein
- Small-subunit processome Utp21 domain-containing protein
- ESF1 RRM domain-containing protein
- Pescadillo homolog
Sequence:
MPKKDLFSSSSSDDSDADDLGQQMAVAAAVEKRRNPHAYDPTSGKRKGKSLEHSTTSVAAVQPLDSSDDDNEAGHDKVEAVNDVGPIDPALKSSTTESTGKPKGKKSKKKKGDVDGANISGDDDDDDDGGIRINKQYAAKYEEVKRRKELQQLTQKYSNRLRGNNGLGDLESDEEDEEDDGAVLLTESKELAFAKTFLAIRQAGLAKKRSGKQAKGSDRNENTKTDSSVSDADAENKILLNTEQRFFPPPEEQVRENTEVFAKAVATKREKRNKFTLADEYRRGVVMSAEKGGANEKDDGEDVGKDESTWGSRRIQPQSEKERKLRESFLQSVAESGESFSVKPAFTPPADQQQSNEESEAKRLLAGAFSIRAPNRDGATTDGDDASANHDADEEFLRDFFVEELWKPENNRKVGKNGSKASRRSSVTAEDGPEPADGGESGGNSASDYEDYEEGNNYAALAELAQAEEDERFFAEAEVWERKFQERAYRHQEENADHVQSFPRAVGSNAEGLLRKTAQSSRKEAHLRRLTRMRELREQQVAELRRLKTLKRQEIEEQRALIASIAGISREKRQNHRDVKVSGGKPSDDEDAAVRRLMSLWSEKDLDEDFDPSKFDSKMSKIFDDNYYDEKNVDEEEIAFFEDEEDINGVGEPEGQGEENEVYKQQLEDGESVEESLLGGGGVAGKGVELAADDAMELLYPTVTMPELEETPATNSREQIERLLRQQKKQPGATDPDEVLEQLQTTLKQKEKEYWQLHHESTLDGGSLKTRFKYRRVVPENFTLSVEEILAQDDRQLNMLVPMNCYAAYLSAEENRRDRIRADKRRRRGFREIDSSRSSRRYGDVSKTSLVDPNMKEEEGEKWAENVRKSLRRLRQGMGLDHEDSLEDENNPGDNMTRSGKRGKSNRGGDSDNRGLNGSTLGYQQKDLRHQKGEGQRGNIGVRSDREGEIREFPRHPGGSRKRQLDDADERDFGGSGGAVEGRRRGVASKPRHE