wanglab/gogpt-training-data huggingface dataset:
Protein: Rho family GTPase (A0A1D8PDV5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Rga2p
- Lrg1p
- Rho family guanine nucleotide exchange factor
- Serine/threonine-protein kinase CST20
- Dck1p
- Actin-binding protein
- Rho GDP-dissociation inhibitor
- Rho GDP-dissociation inhibitor
- Serine/threonine-protein kinase CLA4
- Lmo1p
Sequence:
MRSIKSVVVGDGGVGKTCLLISYTTNTFPNDYIPTVFDNYSASVMIDGEPIKLGLWDTAGQSEYDRLRPLSYPQTEIFLCCFSVISPDSFQNVKSKWIPEILHHCPKDILILLIGTKVDLRDDLHVLDELTARNLSPVTFDQGSKLAREIGAIKYMECSAATQVGVKEIFDYAIRAVLDPPNANKGEYVTNDSVPGMGVNNSSGSKKHNEKNGSGTATAGTGKKRKIKRAKKCTIL
Protein: Calcium-dependent calmodulin-independent protein kinase isoform 1 (Calcium-dependent protein kinase 21-like) (Q7XZK5)
Organism: Cicer arietinum (Chickpea) (Garbanzo)
Interaction partners:
Sequence:
MGCQGSKEKNKPTPDFTARHHGSSATAASASGVATNNHQYHSVQPSSTHVQTPPPKPDSNPKPTVTTQNVKTVHKTDTTILGKPFDDIKKHYTLGQELGRGQFGITYFCTENSTGNTYACKSILKRKLVSKSDREDIKREIQILQHLSGQPNIVEFKGAYEDRFSVHLVMELCAGGELFDRIIAQGHYSERAAASICRAVVNVVHICHFMGVLHRDLKPENFLLSSKDEGATLKATDFGLSVFIEEGKVYRDMVGSAYYVAPEVLRRSYGKEIDIWSAGIILYILLSGVPPFWAETEKGIFNAILEGELDFASEPWPSISDSAKDLVRKMLNHDPKKRITSAQVLEHPWMREGGEASDKPIDSAVLSRMKQFRAMNKLKKLALKIIAENLSEEEIKGLKAMFANMDTDNSGTITYEELKTGLARIGSRLSETEVKQLMELADVDGNGSIDYLEFISATMHRHRLERDEHLYKAFQYFDKDNSGHITREELETAMTQHGMGDEATIKDIISEVDTDHDGRINYEEFCAMMRSGMPPPGTTIINLQSEFDFICSCNSL
Protein: Protein adenylyltransferase SoFic (EC 2.7.7.108) (AMPylator SoFic) (Q8E9K5)
Organism: Shewanella oneidensis (strain ATCC 700550 / JCM 31522 / CIP 106686 / LMG 19005 / NCIMB 14063 / MR-1)
Function: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
Interaction partners:
- HDOD domain-containing protein
Sequence:
MEWQAEQAYNHLPPLPLDSKLAELAETLPILKACIPARAALAELKQAGELLPNQGLLINLLPLLEAQGSSEIENIVTTTDKLFQYAQEDSQADPMTKEALRYRTALYQGFTQLSNRPLCVTTALEICSTIKSVQMDVRKVPGTSLTNQATGEVIYTPPAGESVIRDLLSNWEAFLHNQDDVDPLIKMAMAHYQFEAIHPFIDGNGRTGRVLNILYLIDQQLLSAPILYLSRYIVAHKQDYYRLLLNVTTQQEWQPWIIFILNAVEQTAKWTTHKIAAARELIAHTTEYVRQQLPKIYSHELVQVIFEQPYCRIQNLVESGLAKRQTASVYLKQLCDIGVLEEVQSGKEKLFVHPKFVTLMTKDSNQFSRYAL
Protein: Necrosis-inducing protein NPP1 (Q9AT28)
Organism: Phytophthora nicotianae (Potato buckeye rot agent) (Phytophthora parasitica)
Function: Secreted effector that acts as a pathogen-associated molecular pattern (PAMP) recognized by the plant immune system. Induces necrotic cell death and ethylene biosynthesis in parsley. Stimulates early induced host cellular responses implicated in elicitor signal transmission such as increased levels of cytoplasmic calcium, production of reactive oxygen species (ROS), and MAP kinase activation. Infiltration of NPP1 into leaves of Arabidopsis thaliana results in transcript accumulation of pathogenesis-related (PR) genes, production of ROS and ethylene, callose apposition, and hypersensitive response (HR)-like cell death. NPP1-mediated induction of the PR1 gene is salicylic acid-dependent, and requires both functional NDR1 and PAD4.
Subcellular location: Secreted {ECO:0000305|PubMed:12410815}.
Interaction partners:
Sequence:
MNVLTFLIAAAVSLAVVQADVISHDAVVPFAQPTATTTEQKAGVKFKPQIHISNGCHPYPAVDANGNTSGGLKPTGSSSAGCKGSGYGSQVYGRVATYNGVYAIMYSWYFPKDSPVTGLGHRHDWEHVVVWVDDIKLDSPSIIAVSPSAHSGYNIYYPPESNTIDGYSAKVDYSSSWVVINHALDSTTDAGETQDLIMWDQLTDAARTALENTDFGDANVPMKDGNFLTKVGNAYYA
Protein: Prolactin-induced protein (Q64367)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MASLQKFYQPGAVTYLLIVFLLQETAGFWYHGLHNEPRNYTLTLNMKITPSTSITNKKGNEFRVQLTVKNNVKQCQEVEINTEHERYIKFLSGPSTFETCICTISDFFWDIYVSESTYLTLSASILPYKNKCPDSDEPLLYGDSYQMYNITDKINVTP
Protein: Zinc finger protein 329 (Q86UD4)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MRLKMTTRNFPEREVPCDVEVERFTREVPCLSSLGDGWDCENQEGHLRQSALTLEKPGTQEAICEYPGFGEHLIASSDLPPSQRVLATNGFHAPDSNVSGLDCDPALPSYPKSYADKRTGDSDACGKGFNHSMEVIHGRNPVREKPYKYPESVKSFNHFTSLGHQKIMKRGKKSYEGKNFENIFTLSSSLNENQRNLPGEKQYRCTECGKCFKRNSSLVLHHRTHTGEKPYTCNECGKSFSKNYNLIVHQRIHTGEKPYECSKCGKAFSDGSALTQHQRIHTGEKPYECLECGKTFNRNSSLILHQRTHTGEKPYRCNECGKPFTDISHLTVHLRIHTGEKPYECSKCGKAFRDGSYLTQHERTHTGEKPFECAECGKSFNRNSHLIVHQKIHSGEKPYECKECGKTFIESAYLIRHQRIHTGEKPYGCNQCQKLFRNIAGLIRHQRTHTGEKPYECNQCGKAFRDSSCLTKHQRIHTKETPYQCPECGKSFKQNSHLAVHQRLHSREGPSRCPQCGKMFQKSSSLVRHQRAHLGEQPMET
Protein: Probable E3 ubiquitin ligase SUD1 (EC 2.3.2.27) (Protein ECERIFERUM 9) (Protein SUPPRESSOR OF DRY2 DEFFECTS 1) (AtSUD1) (RING-type E3 ubiquitin transferase SUD1) (RING/U-box domain-containing protein) (F4JKK0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable E3 ubiquitin ligase acting as a positive post-transcriptional regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity. Might be involved in the quality control that degrades misfolded proteins (By similarity).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- RING/FYVE/PHD zinc finger superfamily protein
- ERAD-associated E3 ubiquitin-protein ligase HRD1A
- Exosome complex component RRP45B
- Protein OS-9 homolog
- ERAD-associated E3 ubiquitin-protein ligase HRD1B
- ERAD-associated E3 ubiquitin-protein ligase component HRD3A
- 3-ketoacyl-CoA synthase 6
- Protein ECERIFERUM 2
- E3 ubiquitin-protein ligase RMA1
- Very-long-chain aldehyde decarbonylase CER1
Sequence:
MEISPADSLSISGAAASEVVSEPSVSSSSSSSSPNQASPNPFSNMDPAVSTATGSRYVDDDEDEEDVCRICRNPGDADNPLRYPCACSGSIKFVHQDCLLQWLNHSNARQCEVCKHPFSFSPVYADNAPSRLPFQEFVVGIAMKACHVLQFFLRLSFVLSVWLLTIPFITFWIWRLAFVRTFGEAQRLFLSHISTTVILTDCLHGFLLSASIVFIFLGATSLRDYFRHLRELGGQEERDDDVDRNGARAARRPAGQANRNLAGEGNGEDAGDQGAAVGQIARRNPENVLARLDIQAARLEAQVEQMFDGLDDADGAEDVPFDELVGMQGPVFHLVENAFTVLASNMIFLGVVIFVPFTLGRIILYHVSWLFAAARGPAVAASLHLTDTGLSLENITLKSALTAVSNLTSEGQGNGLLGQLTEMMKVNGSELNGANNTLSVATDLLKGSTVGASKLSDITTLAVGYMFIVFLVFLYLGIIALIRYAKGEPLTVGRFYGIASIVEAVPSLLRQFLAAMRHLMTMIKVAFLLVIELGVFPLMCGWWLDVCTVRMFGKTMSHRVQFLSISPLASSLVHWVVGIMYMLQISIFVSLLRGVLRPGVLYFLRDPADPNYNPFRDLIDDPVHKHARRVLLSVAVYGSLIVMLVFLPVKLAIRMAPSIFPLDISVSDPFTEIPADMLLFQICIPFIIEHFRLRTTIKSLLRCWFTGVGWALGLTDFLLPRPEDNIGQDNGNGEPGRQNRAQVLQVGGPDRAMAALPVADDPNRSRLRAGNVNTGEEYEDDDEQSDSDRYNFVVRIILLLLVAWVTLLLFNSALIVVPVSLGRALFSAIPILPITHGIKCNDLYAFVIGTYAFWTTISGARYAIEHVKSKRTSVLLNQIWKWCGIVFKSSVLLAIWVFIIPVLIGLLFELLVIVPMRVPVDESPVFLLYQDWALGLIFLKIWTRLVMLDHMLPIVDDSWRAKFERVREDGFSRLQGLWVLREIVFPIVMKLLTALCVPYVLARGVFPMLGYPLVVNSAVYRFAWIGCLSVSLFCFCAKRCHVWFRNLHNSIRDDRYLIGRRLHNFGEAALANQNQNQSSEDAGDGVLIGREGDVDNGLRLRRAIQQEA
Protein: Potassium channel subfamily K member 2b (Potassium channel, subfamily K, member 2b) (Zgc:123268) (Q32LX0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Popeye domain-containing protein 1
- Popeye domain-containing 2
- Popeye domain-containing 3.
- Piezo-type mechanosensitive ion channel component.
Sequence:
MRWKTVLSVFLLVVLYLILGATVFKELEQPYETLQKLNILMEKLEFLEQHPCVNSSDLENLVKQVVSALRAGVNPSGNSSNQSSLWDLSNSFFFSGTVITTIGFGNISPHTEVGRIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKAIAKVEGMIDKWNVSQTKIRVISTLLFILFGCLLFVTLPAVIFKHIEGWSALESIYFVVITLTTIGFGDFVAGEAERRHHEESSGGSQLEYLDYYKPLVWFWILVGLAYFAAVLSMIGDWFRVISKKTKEEVGEFRAHAAEWTANVSAEFKETRRRLSVDIYDKFQRATSVKRKLSAEINLSPPINQQMTPGKRARSVNLGDEREAYPYTLARNGSLFLNSLIPDYADHRDMTRIQTK
Protein: LD44526p (Q960M7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTSLELSESVVTPGNCDGSDSGLDVASCCHSRITLQRGLSSTSGGYTSSNGLEEIYDSCELKVTTVAQTPSETGSEKTSPPRRTGSVKKKVAMFEPEPTGTPAKDQLRGRVANLKRAESLPRNSAAPGTPGTPSTHRDKARLSTSSFRVPSTTGTPSSSRLARPQKPDTLPNALNRAQSVQRLTQVQRTPSLSRARTPGTPSDDGRWPANRGAARRGMSVTPEVTTNRMRGSPAPGGTLPRRRKQQSVEDLTGGRLSRSNSISRAAIVDARMTSSVMVVPTSRRSLAPAAAKVNSLRRPQPATPRTRIYHETAVQTALTSEDLEQVLGGGLLQTRAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLNTERVMGMLELARVVSASAGTPTSEDSGDGSGHDSLLMLESQIQISGHELFERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQESSELQDFLQHEKAAQCDALRDLEADYQAVKLQLANREEEAKVLRDECRHLVRLNEQRRQENRLLQTKFTALENKSRELIHQQNASVAGASTALSGLHSRLDGLVEQLVYSYSISEQDLEDIRFQAETEHVQNGQRPNGLDLPICPAASGDAIHTLVLASDGSLSPQRNQSFIAAVIGAIRQATTHSGKRLSLRQAGKKNGVGLGSAQAVSAGTQGQEPQGNGDDSDSTEMLDSETEPCLLMMDNVLEDVVHHDSHSHNMVSSCTGMISQIELPTELISQCSHQNNINGGAGGDDSLQQLSQAITNRQQMELHMHKMNGMPMNPRDQCNTEELSCHDSLAELTELPSLMEYSTAQAVVDQVIEVDTLVTKLLKVLRLVQLDNDNCIQQLIVDKNKLQQHKEDMLEKLKDLEDVNLKLQDELMDATQELMIKGSDLSGAKAEMQRHRNEIDVRF
Protein: Adiponectin receptor 1 (A0A8I6A3X9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKGGRKEERKEGRKEGRKEGRKTDRQTAEEEQACPVPQEEEEEVRVLTLPLQAHHAMEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCTDDSLL
Protein: Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 (EC 1.1.1.8) (GPDH-C) (GPD-C) (P21696)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- Uncharacterized acyltransferase C1718.04
- Glycerol-3-phosphate dehydrogenase [NAD
- Uncharacterized acyltransferase C1851.02
- Putative lysophosphatidic acid:oleoyl-CoA acyltransferase
- Probable diacylglycerol pyrophosphate phosphatase 1
- Dihydroxyacetone kinase 1
- Dihydroxyacetone kinase 2
- Lysophospholipid acyltransferase
- Nuclear elongation and deformation protein 1
Sequence:
MSGYGQQGVSAANIDSIRPKKRLSIGVVGSGNWGTAIAKICGENARAHGHHFRSKVRMWVFEEEIEYKGEKRKLTEVFNEAHENVKYLPGIECPPNVIAVPDVREVARRADILVFVVPHQFIERVCDQMVGLIRPGAVGISCIKGVAVSKEGVRLYSEVISEKLGIYCGVLSGANVANEVAREQFCETTIGFNPPNEVDIPREQIAAVFDRPYFSVVSVDDVAGVALGGALKNVVAMAVGFADGLEWGGNTKAAIMRRGLLEMQKFATTFFDSDPRTMVEQSCGIADLVTSCLGGRNNRCAEAFVKTGKSLETLEKELLGGQLLQGAATSKDVHEFLLTKDMVKDFPLFTAVYNISYEDMDPKDLIIVLQPLKEDSENEGGTETE
Protein: AEL007Wp (Q757M9)
Organism: Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Ashbya gossypii)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Structural maintenance of chromosomes protein
- ADL093Wp
- Structural maintenance of chromosomes protein
- AGL076Wp
- Sister chromatid cohesion protein 2
- Serine/threonine-protein kinase
- separase
- AEL149Cp
- N-acetyltransferase ECO1
- Structural maintenance of chromosomes protein 5
Sequence:
MSQINEHQQSKLLHLQTKTGSLAQIWLASTMTNLNRTYLRTDIVQSVEEISKATTREGGDDGGDPITLRVSGELLHGVVRVYSQKANFLLTDVSDLLHRLKSVFRGNMSRTTAVRVDTVARLDQVVLADTVTEMDVLAMPEIDFLDTTSSSKGLMRRERSMERHVQGANTVTDPWDMSLEVGRRYAPDDDLEQQTSLLDLNFELSDMQNSKSWGEGTHNSEEISANVLAESQRQELPGNEGIEREEDLDWNLGFTEPAIVVPSSDFEHDNSIEVGRRAVPNADLQETVDLGFDLDIAKGDIEATAGEQDAGQLQSELSGSISTSSGTTVSSQRRGQAALVNAKVLQVDHQPELHDRLLRDTPQTAASVDMTAIPLPSPPKKRAYSELASTMDFLPEFALDHFTAFVSQKRRHAESPAARTIAHEVSSAESVDETHIDISLDLNDDLLRSDAIEAGTEEEIEGEDAILDVPSSPRAQTASASPDLHEYSHISTEDVGFSLPRREVEVTTGDHVAKSTVDMANTIRSELMDVESTTFSHLLKSKYGEESGAITKSQASKAFFEMLVLATADCVDLSQQASTGDITITGKGALYEKFIDI
Protein: Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1) (O61735)
Organism: Drosophila melanogaster (Fruit fly)
Function: Circadian regulator that acts as a transcription factor and generates a rhythmic output with a period of about 24 hours. Oscillates in antiphase to the cycling observed for period (PER) and timeless (TIM). According to PubMed:9742131, reaches peak abundance within several hours of the dark-light transition at ZT0 (zeitgeber 0), whereas PubMed:9616122 describes bimodal oscillating expression with maximum at ZT5 and ZT23. Clock-cycle heterodimers activate cycling transcription of PER and TIM by binding to the E-box (5'-CACGTG-3') present in their promoters. Once induced, Period and Timeless block Clock's ability to transactivate their promoters.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Protein cycle
- Protein timeless
- Period circadian protein
- NAD-dependent histone deacetylase sirtuin-1
- Discs overgrown protein kinase
- Cryptochrome-1
- Timeout
- GH23983p
- Transcription factor cwo
- GH27708p
Sequence:
MDDESDDKDDTKSFLCRKSRNLSEKKRRDQFNSLVNDLSALISTSSRKMDKSTVLKSTIAFLKNHNEATDRSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFMMVFSSMGSIFYASESITSQLGYLPQDLYNMTIYDLAYEMDHEALLNIFMNPTPVIEPRQTDISSSNQITFYTHLRRGGMEKVDANAYELVKFVGYFRNDTNTSTGSSSEVSNGSNGQPAVLPRIFQQNPNAEVDKKLVFVGTGRVQNPQLIREMSIIDPTSNEFTSKHSMEWKFLFLDHRAPPIIGYMPFEVLGTSGYDYYHFDDLDSIVACHEELRQTGEGKSCYYRFLTKGQQWIWLQTDYYVSYHQFNSKPDYVVCTHKVVSYAEVLKDSRKEGQKSGNSNSITNNGSSKVIASTGTSSKSASATTTLRDFELSSQNLDSTLLGNSLASLGTETAATSPAVDSSPMWSASAVQPSGSCQINPLKTSRPASSYGNISSTGISPKAKRKCYFYNNRGNDSDSTSMSTDSVTSRQSMMTHVSSQSQRQRSHHREHHRENHHNQSHHHMQQQQQHQNQQQQHQQHQQLQQQLQHTVGTPKMVPLLPIASTQIMAGNACQFPQPAYPLASPQLVAPTFLEPPQYLTAIPMQPVIAPFPVAPVLSPLPVQSQTDMLPDTVVMTPTQSQLQDQLQRKHDELQKLILQQQNELRIVSEQLLLSRYTYLQPMMSMGFAPGNMTAAAVGNLGASGQRGLNFTGSNAVQPQFNQYGFALNSEQMLNQQDQQMMMQQQQNLHTQHQHNLQQQHQSHSQLQQHTQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQLQQQNDILLREDIDDIDAFLNLSPLHSLGSQSTINPFNSSSNNNNQSYNGGSNLNNGNQNNNNRSSNPPQNNNEDSLLSCMQMATESSPSINFHMGISDDGSETQSEDNKMMHTSGSNLVQQQQQQQQQQQILQQHQQQSNSFFSSNPFLNSQNQNQNQLPNDLEILPYQMSQEQSQNLFNSPHTAPGSSQ
Protein: Histone-lysine N-methyltransferase (EC 2.1.1.355) (B0S6M0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR009343}.
Interaction partners:
- protein acetyllysine N-acetyltransferase
- Eukaryotic translation initiation factor 2 subunit 3
- Ribosomal RNA-processing protein 8
- Histone H3.2
- Histone H3
- Histone H3.3
- Damage-specific DNA-binding protein 1.
- Chromodomain Y-like protein
Sequence:
MAENLKAQVCRVACIATTEQLEVVCRDEGVVCEELGISRNNLCDYEVEYLCDYKRKVITDGKRQTVQELYLVKWKGYPESRNTWEPRRNLRCVNLLSQFWEDLNAEMQRQNKRSAPRRLDPATVTHLTQRAKLRQTLKQWETHLNSLGTHKGYISVRNQVDLEGPPKSFTYINDYKVGDGILLNEVSVGCECTDCLASPVEGCCAGASQHKFAYNELGQVRIRPGLPIYECNKRCRCGPDCSNRVVQRGIRYSLCIFRTDNGRGWGVRTMERIRKNTFVMEYVGEIITTEEAERRGHVYDKEGATYLFDLDYVDDEYTVDAAHYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRGIKAGEELTFDYNMKIDPVDAESTKMDTNFGVMGLPGSPKKRMRVECKCGVATCRKYLF
Protein: RINT1-like protein MAG2L (Protein MAIGO 2 homolog) (Protein MAIGO 2-like) (Q8GXP1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May function in the anterograde transport of protein from the endoplasmic reticulum (ER) to the Golgi complex and in the retrograde transport from the Golgi complex to the ER.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9STU3}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9STU3}.
Interaction partners:
- MAG2-interacting protein 2
- Centromere/kinetochore protein zw10 homolog
- At3g24315
- Syntaxin-81
- Homeobox protein LUMINIDEPENDENS
- Membrane fusion protein Use1
- At3g55600
- Sec1 family domain-containing protein MIP3
- Conserved oligomeric Golgi complex subunit 4
- 25.3 kDa vesicle transport protein SEC22-1
Sequence:
MLPMEHPLPLSFVLPNPATLPGLALGFIDGNFVDLQDLLLRASTLTSNLNHDCSDLNDRLLHLRTDLTKHAVSWISTSLSAKVSLEDLRLNLESLLCLPTDSVGKQTNWELQQVVEELCRIQNRRKYFVTALKLESLVGDLEDSVFHPISKRKGSTLQDLALKQERFSHAIKTMNEIEEILGDVTRHHSRWRRLVDSVDSRVDKSLSVLRPQIIADHRAFLSSLGWPPKLATSKVEHGEVDSIPNPLLLMQGDKKESYSQSFLLLCGLQQHNTQKEKRKKLNMTKETDNDGLWATDELVKPVASRMEYHFLKWAEQPEFIFELVYKVTRDFADGVDDFLQPLIDRAMLVSCSAKEAWVSAMVQMLSGFLEKKVFPGLIDMYKEKHMKSEGISSWFHLVDQMVTFDKRMQSFVNTDTCLSYEGSSTAFSQGISVMGLFCKKPEWLKTWGKIELKDAYRKSKEDIKNEKAWVIDSERTRLGNESNSQSAKYVLSTREDYKAPLVADSFLNRTWRLIDHGLSLPAILPRIQFIRATATRFLWCIFKILLLEFKKTDLSHYGLSEDTLIQACGPVNAARYLESKLREWSDDLVFVEMWAAETSVKVDRKPEVSCQGCFFGEELKSLVELETNWLMEIITVFLHQFDNLCSDHFHNNAVSWDEDVITSSSNLTVSQGVAEALDNLRRHLCVLHLNMNPKDFLDLWRNLAEGLDHYVSRKFFSGEPVLRRQKFDRFEVDAEALLTVLKPYCVRPGAFFPRVREILRLLRMHEEEKARLRGALSRSGNTCLKLFGISNLSPQLVEQFCRSY
Protein: Endomucin (Endomucin-1/2) (Mucin-14) (MUC-14) (Q9R0H2)
Organism: Mus musculus (Mouse)
Function: Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Platelet endothelial cell adhesion molecule
- Cadherin-5
- Lymphatic vessel endothelial hyaluronic acid receptor 1
- Angiopoietin-1 receptor
- Roundabout homolog 4
- Adhesion G protein-coupled receptor L4
- Transcription factor SOX-18
- Podocalyxin
- CMRF35-like molecule 9
- Glycosylation-dependent cell adhesion molecule 1
Sequence:
MRLLQATVLFFLLSNSLCHSEDGKDVQNDSIPTPAETSTTKASVTIPGIVSVTNPNKPADGTPPEGTTKSDVSQTSLVTTINSLTTPKHEVGTTTEGPLRNESSTMKITVPNTPTSNANSTLPGSQNKTENQSSIRTTEISVTTQLLDALPKITATSSASLTTAHTMSLLQDTEDRKIATTPSTTPSYSSIILPVVIALVVITLLVFTLVGLYRICWKRDPGTPENGNDQPQSDKESVKLLTVKTISHESGEHSAQGKTKN
Protein: Signal peptide peptidase 2 (OsSPP2) (EC 3.4.23.-) (Intramembrane protease 2) (IMP) (IMPAS) (B9FJ61)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19688213}; Multi-pass membrane protein {ECO:0000269|PubMed:19688213}.
Interaction partners:
Sequence:
MKTHERAANLALAGLSLAPLVVKVNPNANVILTACLAVYVGCYRSVKPTPPAETMSKEHAMRFPLVGSAMLLSLFLLFKFLSKDLVNTVLTAYFFILGIAALCATLLPSIKRFLPKEWNDNAIVWRAPLFHSLSVEFTRSQVVASIPGFFFCIWYAAKKHWLANNVLGISFCIQGIEMLSLGSFKTGAILLSGLFFYDIFWVFFTPVMVSVAKSFDAPIKLLFPTGDAARPFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTVGLTVTIIVMNWFQAAQPALLYIVPGVIGFVAVHCLWNGEVKPLLEYNESKAEEEEACEEDTDSKQNKKKE
Protein: Proline-rich 28 kDa antigen (P9WIM9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Exported repetitive protein
- Conserved hypothetical proline and threonine rich protein
- Peptidoglycan endopeptidase RipA
- Biotinylated protein TB7.3
- Possible conserved transmembrane alanine and glycine rich protein
- Uncharacterized protein Rv0039c
- Conserved hypothetical ala-, pro-rich protein
- Possible Inv protein
- Peptidoglycan endopeptidase RipB
- Leucine--tRNA ligase
Sequence:
MIQIARTWRVFAGGMATGFIGVVLVTAGKASADPLLPPPPIPAPVSAPATVPPVQNLTALPGGSSNRFSPAPAPAPIASPIPVGAPGSTAVPPLPPPVTPAISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAFVVIADRLGNSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTTNASMANFDGFPSSIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVTTALSQAVTDGPATDAIVNGFQVVAHAAPAQAPAPAPGSAPVGLPGQAPGYPPAGTLTPVPPR
Protein: Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) (Q91250)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Function: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Subcellular location: Nucleus.
Interaction partners:
- histone acetyltransferase
- Estrogen receptor 2
- Progesterone receptor
- Nuclear receptor interacting protein 1
- histone acetyltransferase
- RING-type E3 ubiquitin transferase
- Nuclear receptor coactivator
- Tyrosine-protein kinase
- Nuclear receptor coactivator
- Probable ATP-dependent RNA helicase DDX5
Sequence:
MTLHTKTSGVTLLHQIQGTELETLSRPQLKIPLERSLSDMYVETNKTGVFNYPEGATYDFGTTAPVYSSTTLSYAPTSESFGSSSLAGFHSLNSVPPSPVVFLQTAPHWSPFIHHHSQQVPYYLENDQGSFGMREAAPPAFYRPNSDNRRHSIRERMSSANEKGSLSMESTKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRVMKQKRQREEQDSRNGEASSTELRAPTLWASPLVVKHNKKNSPALSLTAEQMVSALLEAEPPLVYSEYDPNRPFNEASMMTLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATAARFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDYIHRVLDKITDTLIHLMAKSGLSLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAPAARSAAPMEEENRSQLTTASASSHSLQSFYINSKEEENMQNTL
Protein: Uncharacterized protein (Q580R6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSVWQKWKLSTAADGKFGLRPFLIRFVNVWPLRCDTTWLGKPPVKTFPSFWANVACLSDRERDFFVQCVEHICFGIGMSATPAIKDVMNRLADGAGIHNLQGLSTTERESHTDILCDVVLMHDGKPCMGWFADNYGDRNFNNIIEVLEERWNISPASLWALKERNIAEQMNTMTHYNRQESIFCNSDGLTEGKLASLVKRHVRFADKNICIDVKSISEIRSLSLSLLEEPTVEKREILLQCLSNVVPELITKPGKVSPCSTVLKAFGCFLAPSVRKLDIPLDSVYELGSTLCSIPADDVTTHVFQRHIRHLLDITEGKQICASGPDQQHMLRDTLNNLESVGHDLDQVFVCFSQAVALCQVVEDPTERDDALCRILLAIPLIERYITSYESAILRQHTFSDSCLPSHVEPNHSNREVCLLDSFALDRVICASNCREQGANASADSSSAFDSTKGKPFDGCCGFWMPGMGLDSSCYVTDLLSACTDLANMLGVPASRCDIVTESQRLVYDIRHKLRVHTLRRFAFVKASKVWNSALRKRALPFLNALRSSLYEAPALTILRFRDGERLPNTFGAASEPSSLLQSLSSLHVCFAFSTPAFYVECGTIQELEAMCVTQPLSAMRRLKCFSSPSSSTGISSVVEVPVPSNLVDSLLVCAKAQLQLKPEHGFVDVAFQRDGDHATVVPSCLDKLLRGQKA
Protein: Stb5p (Q5A926)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RNA polymerase II holoenzyme cyclin-like subunit
- Serine/threonine-protein kinase SSN3
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 7
Sequence:
MRPIDSIVSKFRVQKHTSNLADNPAVLKHPEDMPKLTSCLRCRKLKKKCDKSTPHCLNCENANEECTYVKRKPRQSKNGKTTTSESSLDPPSPMVNETFTGFSYLNQSQPNDLFRHIPSATTNTSTTTSTVAAAVPPTTNTSESVSSSRSHTPPILNSIDARAPNFHSYPKQISKVLISAVGIKTNSNVSIIPPIVDKDLLTSIIGSFMQHNYRICPVIHKKEFLENFQKLFKEDGIVDLDSHHDPYELYMVLAVGSTGLERTGIISRDKKLSEYFVSMALSHVHNNLSTNSLTNVRNLTLLALYSFFNPAEYTSWEIMGKLTRLAIHLGMNHKISDQDARNLSSKEIEMRSRLFWSVYNIDRLSSVSLGRPVALQDDDINVPFPQVLEEDETEDIAVNRLVINLRRLEGKILRRVHSVNIYKNFINKDKSQEEVCQEILSDLRKEIEDWYYQVKSVDNANTSVRQSVSFHLSVPWYTARYNHLLILLYRPSYLNPRPSQDLLDILGKSCLETLSYTYKLFKAKLLPLNWTTLYRFLMVCTTILYCLCKWAIDLMESKTEICYCIEIFQAFGSDWIVAKKCAEVFRKIENKLLEITLSDGHVSDMDNLSKELLGASSSYHEILNVHSVDLCIDTDFMYNF
Protein: Coiled-coil domain-containing protein 86 (Cytokine-induced protein with coiled-coil domain) (mCyclon) (Q9JJ89)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000269|PubMed:17300783}.
Interaction partners:
- mRNA turnover protein 4 homolog
Sequence:
MDTPLRRSRRLEGLKPLSPENLPVPEVSRAKRALVDFKSNSEETGELKSTRVPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPEASPGSPGPRQDADDGSPQRQPEPHPGSLQPHQDLGLESPAGQTESSPESPQREQPSKLPPPQGELDSEAAHAKEEVIPGSPEPCPGQQAPGPEPSQPAQELTVQAPSSPERQLEPGKLPPAGETVTESLNLKKRVIASPQAPASKKLKEKEELPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKQRRRQEKKERRAENLRRRLENERKAEIVQVIRNPAKLKKAKKKQLRSIEKRDTLALLQKQPPQRPVAKV