wanglab/gogpt-training-data huggingface dataset:
Protein: tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (Pa-Kae1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1) (tRNA threonylcarbamoyladenosine biosynthesis protein Kae1) (Q9UXT7)
Organism: Pyrococcus abyssi (strain GE5 / Orsay)
Function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. In vitro, binds tRNA, ssRNA, both single- and double-stranded DNA, and exhibits a low ATPase activity.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01446}.
Interaction partners:
- KEOPS complex subunit Bud32
- KEOPS complex subunit Pcc1
- KEOPS complex subunit Cgi121
- Glycerol kinase
- DUF835 domain-containing protein
- Ribokinase
- Threonylcarbamoyl-AMP synthase
- Small ribosomal subunit protein uS13
- Probable translation initiation factor IF-2
Sequence:
MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDEVEIVW
Protein: Hemin/hemoglobin-binding protein 1 (Hn/Hb-binding protein 1) (Cell wall protein Lmo2186) (Q8Y585)
Organism: Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Function: Binds both host hemin and hemoglobin with affinity in the nanomolar range and presumably directs it to membrane transporters.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:16247833, ECO:0000269|PubMed:19129190}; Peptidoglycan-anchor {ECO:0000269|PubMed:16247833, ECO:0000269|PubMed:19129190}. Secreted {ECO:0000269|PubMed:19129190}.
Interaction partners:
- Sortase B
- Hemin/hemoglobin-binding protein 2
- High-affinity heme uptake system protein IsdE
- Probable heme-iron transport system permease protein IsdF
Sequence:
MKKVLVFAAFIVLFSFSFLSTGLTAQAALKDGTYSVDYTVIQGDSDSASMANDYFDKPATVTVNGGKSTVSLQVNHSKWITGLWVEGNAVSVTSKNASSDTRKVSFPVSTLSNPVNAKIKVDIDDDDLNYHHEYQIKLRFDEGSAKALAGAVKSSDNNTTTPATKSDSSNKVTNPKSSDSSQMFLYGIIFVATGAGLILLKRRAIFK
Protein: Uncharacterized protein (Q382K5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPPLNSRATRELVKRRRTIPGPRSLHRGIHYHEATEATETFRKNPKTPKQDHRDLLVHHQKINEQLQDVYARTAALHAPDATMEERIEESWRQFERIGGKRPASVGGCGSRSVVNSGSGGGAPASPHTRTYDHLRNNKTGVGFAERLRLLAGEKKDLRQRASWERETHGEAVDYTQGSALHAAKDRRIALFQRRQLKRAHLLRRMGDPTPLKQSGRYDLNSGTLRVFNKTIRRVQREVKHDERIREVKVRKGSDKSGSIWAPRGGDENPNRPSQGIIRYTREFDLGPRRTGLGKRRKGRGKR
Protein: Large ribosomal subunit protein bL32c (50S ribosomal protein L32, chloroplastic) (P0C454)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS11c
- Small ribosomal subunit protein bS16c
- Large ribosomal subunit protein bL20c
- Os01g0278900 protein
- Large ribosomal subunit protein bL33c
- DNA-directed RNA polymerase subunit alpha
- Large ribosomal subunit protein uL22c
- Large ribosomal subunit protein bL36c
- Large ribosomal subunit protein uL22c
- Os07g0273150 protein
Sequence:
MAVPKKRTSMSKKRIRKNLWKKKTYFSIVQSYSLAKSRSFSGVSEHPKPKGFSRQQTNNRVLG
Protein: Putative methyltransferase YfdM (EC 2.1.1.-) (P76509)
Organism: Escherichia coli (strain K12)
Interaction partners:
Sequence:
MSNKYCQALVELRNKPAHELKEVGDQWRTPDNIFWGINTLFGPFVLDLFTDGDNAKCAAYYTAEDNALAHDWSERLAELKGAAFGNPPYPW
Protein: Thiamine pyrophosphokinase 2 (AtTPK2) (EC 2.7.6.2) (Thiamine kinase 2) (F4IV16)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP). TPP is an active cofactor for enzymes involved in glycolysis and energy production. Plant leaves require high levels of TPP for photosynthesis and carbohydrate metabolism.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:17611796}.
Interaction partners:
- Bifunctional TH2 protein, mitochondrial
- Small ribosomal subunit biogenesis GTPase RsgA 1, mitochondrial
- Thiamine biosynthetic bifunctional enzyme TH1
- Adenylate kinase 4
- Phosphomethylpyrimidine synthase, chloroplastic
- Hydroxyethylthiazole kinase
- Adenylate kinase 1, chloroplastic
- Probable adenylate kinase 6, chloroplastic
- Probable adenylate kinase 7, mitochondrial
- Adenylate kinase 5, chloroplastic
Sequence:
MLSAMDVMIHSSSFLLPCDETCGTRYALVVLNQNLPRFTPLLWEHAKLRLCADGGANRIYDELPLFFPHEDPFVIRNRYKPDVIKGDMDSIRRDVLDFYVYWGTKVIDESHDQDTTDLDKCISYIRHSTLNQESSRLQILATGALGGRFDHEAGNLNVLYRYPDTRIVLLSDDCLIQLLPKTHRHEIHIHSSLQGPHCGLIPIGTPSANTTTSGLKWDLSNTEMRFGGLISTSNLVKEEIITVESDSDLLWTISIKKTGLPVQDHKP
Protein: Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-) (Q9CYH5)
Organism: Mus musculus (Mouse)
Function: Promotes matrix assembly.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:18757743}.
Interaction partners:
- dTDP-D-glucose 4,6-dehydratase
- TBCC domain-containing protein 1
Sequence:
MKLLPGVGVFGTGSSARVLVPLLRAEGFTVEALWGKTEEEAKQLAEEMNITFYTSRTDDVLLHQDVDLVCINIPPPLTRQISVKALGIGKNVVCEKAATSMDAFRMVTASRYYPQLMSLVGNVLRFLPAFVRMKQLIAEHYVGAVMICDARIYSGSLLSPSYGWICDELMGGGGLHTMGTYIVDLLTHLTGQKAEKVHGLLKTFVRQNATIRGIRHVTSDDFCFFQMLMGGGVCSTVTLNFNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSAAQEELLVRDSLAVGAGLPEQGPQDVPLLYLKGMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEWETVEMLAEEPDANQNLSETLQRNNL
Protein: Eyes absent homolog (EC 3.1.3.48) (E9QIR1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MENTQDLNEQSVKKSTTDSHAPDPVDNRALEMQELTDVQHSVNSGSDGTSKLDKNILSNNITTNGTGVKSEPLNSSEAVSSAGDSGLDTYTGSVISSSGFSPRPAHQYSPPLYPSKPYPHILTTPVAPPMSAYTGQSQFSSMQQSTVYTPYSQTTPPYGLSTYATDLGVMLPGIKTEGGLTQTQSTLQSGLSYSPGFTTPQPGQTAYSPYQMPAGSGFTTSPGLYTSNNSNPGNFTTQQQEYPSYTTFGQNQYAQYYSTSSYGSYMTSNSSLDGTGSVSTYQLQDPIMTGQAADLNPGEFEAGQSPSTPIKEMEDRACRGGGAKARGRGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATSASLCLATGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERVMQRFGRKVVYVVIGDGVEEEQAAAKHNMPFWRISSHSDLLALHQALEFEYL
Protein: Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (RA42) (P23944)
Organism: Rattus norvegicus (Rat)
Function: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-13
- Guanine nucleotide-binding protein subunit alpha-12
- Guanine nucleotide-binding protein subunit alpha-11
- Alpha-1A adrenergic receptor
- Beta-2-syntrophin
- Guanine nucleotide-binding protein subunit alpha
- Beta-1-syntrophin
- Voltage-dependent P/Q-type calcium channel subunit alpha-1A
Sequence:
MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKPASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDYSNLRETDI
Protein: Ribosome protection protein VmlR (Multidrug resistance system ATP-binding protein VmlR) (P39115)
Organism: Bacillus subtilis (strain 168)
Function: Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics. Makes contact with the PTC and both ribosomal subunits. Induces conformational changes in the P-site, which allows it to dislodge the antibiotic from its PTC binding site. Binds to ribosomes either directly following translation initation or subsequent to E tRNA release during elongation. Involved in resistance to a narrow spectrum of antibiotics (the streptogramin A antibiotic virginiamycin M, the lincosamide antibiotic lincomycin and the pleuromutilin antibiotic tiamulin).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00846, ECO:0000269|PubMed:30597160}. Note=Does not stably associate with ribosomes. {ECO:0000255|HAMAP-Rule:MF_00846, ECO:0000269|PubMed:30597160}.
Interaction partners:
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL3
- Small ribosomal subunit protein uS15
- Large ribosomal subunit protein bL21
- Large ribosomal subunit protein uL13
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein bL20
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein uL16
- Large ribosomal subunit protein bL27
Sequence:
MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQILRKDIKLALVEQETAAYSFADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSEDADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDRYFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEYHRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKAFGERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQWTEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNGIEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKELDHQDKKD
Protein: Uncharacterized ATP-dependent helicase C23E6.02 (EC 3.6.4.-) (O60177)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Ubiquitin-like protein pmt3/smt3
Sequence:
MRNNTAFEQFTLNPCEQIPLDDKHNIGFNKNNTPDYSSSASSDQLLKNDINRHEMERRIAFLNRKQALFNAFMHDSSSSLNTMESNIEKVNGLFPNDNSVIALKPNEEKLNSSLSVENNDSTYTDATLIAPKIGLDRPNINAITIDVDGHSLQNEISSSTDKLSPSQSDALFEQKQDSLFWNDNAVIVVSDSESDDNNVRTKSSLNDHDKVNMKEKRNLELAFMNSKRKKLELPSLPVLSTAGPSYTNSLALPPFHHHNNYKMFNTTHTLEDDKFLQGKGTSNNPISLSDEEDNEINFQNKRYGSDSVILPGGLLHDSKLPEPGKHLFHLQWYHDRFHNIEGFNLSDSNNQKVQDDQQQQLEELFKDLDEQLVNDPTIREGTPAGLIPTLMEHQKEGLMWLKRLEESSKKGGILADDMGLGKTVQALALLVTRPPESKSVKTTLIITPVSLLQQWHNEILTKIAPSHRPTVYIHHGSSKKHKIAEQLMSYDIVLTTYNVIAYEFKNKMAYDKSIEDNAPIKKFEHLPFFEAEWYRVILDEAQTIKNRNTLAARGCCLLESTYRWCLSGTPMQNGVEEFYSLIKFLRIKPYSDWSSFSKDFTIPLSSNINTSAPMKRFRGLLKAVLLRRTKNTKIDGKPILTLPPKTAVKSETDLSSSEMEFYNTLQSGAQIQMRKYLQEGTITTHYGSLLVLLLRLRQACCHPWLIVAREAAVDDNDSFQAKNRAIYNQIYPEAVNRLKLIETLQCSLCMDVVAELLIIVPCGHFLCRECLTHVITSSEDMAKQTSNENISPKCSVCEEYIDTERLLSYALFRRYSGMAPIVDADNKLRTENISELLPKQYSNILENRQMGMKIFTDPKHWTTSTKIEKALNAVKEIIKKQPTDKILIFSQFVSFLELFTVPFRQEGIKYLMYTGGLSTAERNQALINFEVDPNVRVLLISLKAGNVGLNLTCANHVIILDPFWNPYIEEQAVDRAHRIGQDKPVNILRIVTNNTIEERVLALQDRKRELIDSALGEKGLREISRLNTKELSFLFGMSSR
Protein: LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (Xlim1) (x-Lhx1) (xLIM-1) (P29674)
Organism: Xenopus laevis (African clawed frog)
Function: Involved in the establishment of the body plan via the Spemann organizer during gastrulation. Transcriptional activator required to induce organizer gene expression downstream of siamois. Promotes head formation by binding to 5'-TAAT'-3' elements in the promoters of head organizer genes cer1 and gsc to stimulate expression. Binds as a complex with siamois and mix-A/mix.1 to the cer1 promoter, and with ldb1 and otx2 to the gsc promoter. Also involved in neural induction via the organizer, including a role in notochord formation. Acts synergistically with ldb1 and ssbp in subsequent axis formation. Involved in kidney development, acting synergistically with pax8 to establish the pronephric primordium in late gastrulae/early neurulae and with pax2 during pronephric morphogenesis in tailbud stages. Has a later role in mediating the activity of inhibitors of ventralization.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:8793615}.
Interaction partners:
Sequence:
MVHCAGCERPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLNNNNAAKENSFISVTGSDPSLSPESQDPLQDDAKDSESANVSDKEAGINENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFAFYGDYQSEYYGPGSNYDFFPQGPPSSQAQTPVDLPFVPSSVPAGTPLGAMDHPIPGHHPSSDAQRFTDIMSHPPGDSPSPEPNLPGSMHSMSAEVFGQSPPFSSLSVNGGYGNHLSHPPEMNETAVW
Protein: MAPK interacting serine/threonine kinase 1 (A0A499FIS5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
Protein: At1g17100 (SOUL heme-binding family protein) (SOUL-like protein) (Similar to SOUL Protein) (Q9SHG8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ankyrin repeat family protein
- Ankyrin repeat family protein
- Farnesylcysteine lyase
Sequence:
MATGLGFFKLSFLLSLLSGGSDLLGPDAESGVAQIGKFPPSCNRIECPSYELVHSGNGYEIRRYNNTVWVSTEPIPDISLVDATRTAFFQLFAYIQGKNEYHQKIEMTAPVISQVSPSDGPFCESSFTVSFYVPKKNQPDPAPSENLHIQKWNSRYVAVRQFSGFVSDDSIGEQAAALDSSLKGTAWANAIAKSKEDGGVGSDSAYTVAQYNSPFEFSGRVNEIWLPFELDV
Protein: GH23156p (Islet cell autoantigen 69 kDa, isoform A) (Islet cell autoantigen 69 kDa, isoform B) (Q9VP78)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- PRKCA-binding protein
- Ras-related protein Rab-2
- Dymeclin
- phospholipase A2
- HL02043p
Sequence:
MLKSEVQHQFWITKKVVQRKLGTKEDKHIISSDAELDSKIEVFKSISDTSLNLCKIIDQYQERLCILSQEECVFGRFLKEAGKRSRTTGGSIAHTAKAVSFAGQQRMCVRVPLLRLQHEVDVFRCRAIKDTEQTLQTMEKERTEYRAALSWMKSASQELDPDTGKGLDKFRTAQAHVRVAKHNFDGYSMDSIQKIDLLAAARCNMYSHALVAYVTELKNFAQKAASTFQTISKALIIKPKYDFCVLKELSQNEGSTEEVPPIEAVDKDQSLFFANEYQDKLETQPEIKESEEDKPSAPPNACGDNESLLIELSKQLEDSPLIDAPLDEDIPAQNSTNKLWSRLFSQQNQQPIPSQVATDSKASAGGATPVPSKSQTTNNPWLDLFADLDPLANPQAFDLKLSGGRSVAEQT
Protein: T cell receptor alpha chain constant (P01848)
Organism: Homo sapiens (Human)
Function: Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation. The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity.
Subcellular location: Cell membrane {ECO:0000303|PubMed:20452950}.
Interaction partners:
Sequence:
IQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKTVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESSCDVKLVEKSFETDTNLNFQNLSVIGFRILLLKVAGFNLLMTLRLWSS
Protein: Chloride channel protein (Q389H3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
Interaction partners:
Sequence:
MPLLEERHDLSLRQKLQATIPTRHPRFYSSEERRKMERYESVDTFEPATTVYKDHLAGRSQEPRWFIWVFVVVIGIAVSFTAIVVVALLHVFASVRYELLGYGLNNFSFYNPNRYPERSPDHAELDFTAMFEGVGVGLYGISPRSYMKGYLMWVSFSFVTSLISSVICICVPGSVGAGMPEVMAYLNGVDYPMLGSFGVLLAKIASVVFSVASGVCTGHCGTLMLTGAMVGAQTLQRRRWIQIEHVNIIECFRNPRDRRTIVVIGAAAGIASAFNVSIGGLMVVVELISTTIPVRFALYVFAASLVSSLFIQVYFSHFLYFAGRDRTGYSSGELISELVQVFASTIPFEQIVRMHILYFIPTVVIGFICGALSGVYVRLSWFALVVRRHLEQRFKVRAFRALLPVAFTVAYVSLHYWMVVAFGSAGWSPPSSALNPTDNTTAGGLTTLRWGNSSAVSPHFVDTQSGPCVAVPQTLSDSRDVSVISFYGANGFFCAAPNNTVIPVTATVHEQQVWIVLHSYASLAFANADSALQTLLSLRTETMLSLPVLMIFLLIYYTSSAIFLGISPCGDTVFPTLVVGATVGRIVGLVVFLIVSPGSRSSWADPGIFALIGAGSFVGGTTGLAFSICTILMESTGQFQHMLPLMVGIMIAKKTAEIFTHNINAVLLEARCVPMLNYMNVVEKYPMFDARHVMSSKVVVLETVTPIGRVVDVLENTRHNAFPIESVRDQTYKGVVMRRQLEIVLWHLYYSHHLSTCSYECGKRVEASLYRDNLHGVLPPLEKWLDAQLDLSPYIDYSGFCVLATATLPRTYQMFLTLGLRHLTVVDSGNRIVGIITRKDLMADRIIESIIRTDRRRRRIQGSRKHSTNTGSSDVADVEVAGGEESSEVASGRSASGWEAALKYEFYRSGEWCVSDEEDRVSENNSIREEPGGTWKPDATF
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q5I6E8)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Interaction partners:
Sequence:
MLALVGGEGDMEQEFDAKLKIQNNSANTQRSKSFAFRAPQENFTIQDFELGKIYGVGSYSKVVRAKKKDTANVYALKIMDKKFITKENKTAYVKLERIVLDQLDHPGVVRLFFTFQDTFSLYMALESCEGGELFDQITRKGRLSEDEARFYAAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSRITVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIRFPNYFSNEARDIIDQLLDVDPSRRPGAGPDGYASLKNHPFFSGIDWENLRLQTPPRLAMEPKAPSTHSSGDEQDPSWNPSHIGDGSVRPNDGNGAAASVSEAGNSITRLASIDSFDSKWKQFLDPGESVLMISMVKKLQKLTSKKVQLILTNKPKLIYVDPSKLVIKGNIIWSDNPNDLSIQVTSPSQFKICTPKKVMSFEDAKNRAQQWKKAIEALQNR
Protein: Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (B3DJW5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
Interaction partners:
- Aromatic-L-amino-acid decarboxylase
- Pterin-4-alpha-carbinolamine dehydratase
- Transporter
- Dopamine beta-hydroxylase
- Quinoid dihydropteridine reductase b1.
- Dihydropteridine reductase
- Zgc:171517.
- Sepiapterin reductase
- Aspartate aminotransferase.
- Aspartate aminotransferase, mitochondrial
Sequence:
MPNSSSSTSSTKSIRRAASELERSDSITSQKFVGRRQSLIEDARKEREAAAAAAEAAGLSEQIVFEESDGKALISLFFTLRCSKSPALSRTLKVFETFEAKIHHLETRPSRKPKDGLEDLEYYVQCEVHLSDVSTLVSSLKRSAEDVKTTKEVKFHWFPRKIAELDKCHHLVTKYDPDLDQDHPGFTDPVYRKRRKMIGDIAFKYRHGEPIPRVDYTEEEIGTWREVYSTLRDLYTTHACSEHLEAFRLLEKHCGYSPDNIPQLEDVSCFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCVHELLGHVPILSDRTFAQFSQSIGLASLGASDEDIEKLSTMYWFTVEFGLCKQGGVIKAYGAGLLSSYGELVHSLSDEPERREFDPDIVAVQPYQDQTYQPVYFVSESFVDATEKLRTYVTRIKRPFSVRFDPYTDSIEVLDNPLKIQKGLETIKDELKILTDALNVLA
Protein: YY1AP-related protein2 (A4PB68)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFEVQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGKGKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGARQSYRRKRRGVSQLKPLHLLKSPLMKEPQGQM
Protein: Transcription factor 7-like 1-A (HMG box transcription factor 3-A) (TCF-3-A) (xTcf-3) (P70062)
Organism: Xenopus laevis (African clawed frog)
Function: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling. Also required during development of the CNS for the establishment of dorsal-ventral patterning in the prospective diencephalon.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
Sequence:
MPQLNSGGGDELGANDELIRFKDEGEQEEKSPGEGSAEGDLADVKSSLVNESENHSSDSDSEVERRPPPREAFEKHRDYLTEALRRQQDAAFFKGPPYAGYPFLMIPDLGGHYLPNGALSPSARTYLQMKWPLLDSPSTAGLKDARSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNEHFSPGTPPGHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPPQGQPMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVPPPHHSLHTSGIPHPAIVSPIVKQEPSSGNISPNLHTKSNMIVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPSWSARDNYGKRKKRKREKQSPEMETHTKTKKMCVQHLPADKSCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQLSLSHSAAFLASKSPSSSSFSGHLSSPVGSPLLSRPIPLTSSILSPSGVFPSALQALPLLQAQPLSLVTKSSD
Protein: Dpr-interacting protein beta, isoform C (Dpr-interacting protein beta, isoform F) (B7Z153)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Defective proboscis extension response 8, isoform A
- Defective proboscis extension response 6, isoform F
- Defective proboscis extension response 11, isoform B
- Common Dpr-interacting protein
- Defective proboscis extension response 9, isoform A
- Defective proboscis extension response 15, isoform A
- Defective proboscis extension response 3, isoform B
Sequence:
MMNLLVVKESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLGTGTGTGSGCGPAIRWQLLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEVVIPPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEMERPGKKILRDDDLNEVSKNEVVQKDTRSEDGSRNLNGRLYKDRAPDQHPASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAGPTTLSCRTKGGRQKKAKETSWNGRRARDGREDGHAAEWRQCWERSALSWRRSAPPELDYYSLIQL
Protein: DEAD/H-box helicase 11 (F5GXL6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPLDGVRDSGMASRGPAAKDGENMVSASQKKGEIWSMANETQKVGAIHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDFEQKKREEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRLKAEQARRKQREERLQQLQHRVQLKY