Protein: Calpain-type cysteine protease DEK1 (EC 3.4.22.-) (Phytocalpain DEK1) (Protein DEFECTIVE KERNEL 1) (AtDEK1) (Protein EMBRYO DEFECTIVE 1275) (Protein EMBRYO DEFECTIVE 80) (Q8RVL2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protease involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active. Required for the formation of giant cells in sepals by determining cell fate and promoting endoreplication.
Subcellular location: Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm.
Interaction partners:
- Serine/threonine-protein kinase-like protein ACR4
- Homeobox-leucine zipper protein MERISTEM L1
- Probable calcium-binding protein CML49
- Probable calcium-binding protein CML48
- Probable calcium-binding protein CML50
- Protein MID1-COMPLEMENTING ACTIVITY 2
- At1g64490
- Gb|AAF32471.1
- F16B3.27 protein
- Mediator-associated protein 3
Sequence:
MEGDERGVLLACVISGTLFTVFGSGSFWILWAVNWRPWRLYSWIFARKWPKVLQGPQLDILCGVLSLFAWIVVVSPIAILIGWGSWLIVILDRHIIGLAIIMAGTALLLAFYSIMLWWRTQWQSSRAVALLLLLGVALLCAYELCAVYVTAGAHASQQYSPSGFFFGVSAIALAINMLFICRMVFNGNGLDVDEYVRRAYKFAYSDCIEVGPVACLPEPPDPNELYPRQTSRASHLGLLYLGSLVVLLAYSVLYGLTARESRWLGGITSAAVIVLDWNIGACLYGFKLLQNRVLALFVAGISRLFLICFGIHYWYLGHCISYIFVASVLSGAAVSRHLSITDPSAARRDALQSTVIRLREGFRRKEQNSSSSSSDGCGSSIKRSSSIDAGHTGCTNEANRTAESCTADNLTRTGSSQEGINSDKSEESGRPSLGLRSSSCRSVVQEPEAGTSYFMDKVSDQNNTLVVCSSSGLDSQGYESSTSNSANQQLLDMNLALAFQDQLNNPRIASILKKKAKEGDLELTNLLQDKGLDPNFAVMLKEKNLDPTILALLQRSSLDADRDHRDNTDITIIDSNSVDNTLPNQISLSEELRLRGLEKWLKLSRLLLHHVAGTPERAWGLFSLVFILETIIVAIFRPKTITIINSSHQQFEFGFSVLLLSPVVCSIMAFLRSLQVEEMALTSKSRKYGFVAWLLSTSVGLSLSFLSKSSVLLGISLTVPLMAACLSIAVPIWMHNGYQFWVPQLSCGDQARDLRSPRIKGFILWICVVLFAGSVISLGAIISAKPLDDLKYKLFSARENNVTSPYTSSVYLGWAMSSGIALVVTAILPIVSWFATYRFSHSSAVCLMIFSVVLVAFCGTSYLEVVKSRDDQLPTKGDFLAALLPLACIPALLSLCCGMVKWKDDCWILSRGVYVFFSIGLLLLFGAIAAVIAVKPWTIGVSFLLVLFLMVVTIGVIHLWASNNFYLTRKQTSFVCFLALLLGLAAFLLGWHQDKAFAGASVGYFTFLSLLAGRALAVLLSPPIVVYSPRVLPVYVYDAHADCGKNVSAAFLVLYGIALATEGWGVVASLIIYPPFAGAAVSAITLVVAFGFAVSRPCLTLEMMEVAVRFLSKDTIVQAISRSATKTRNALSGTYSAPQRSASSAALLVGDPSAMRDKAGNFVLPRDDVMKLRDRLRNEERVAGSIFYKMQCRKGFRHEPPTNVDYRRDMCAHARVLALEEAIDTEWVYMWDKFGGYLLLLLGLTAKAERVQDEVRLRLFLDSIGFSDLSARKISKWKPEDRRQFEIIQESYLREKEMEEESLMQRREEEGRGKERRKALLEKEERKWKEIEASLIPSIPNAGSREAAAMAAAIRAVGGDSVLEDSFARERVSGIARRIRTAQLERRAQQTGISGAVCVLDDEPMISGKHCGQMDSSVCQSQKISFSVTAMIQSDSGPVCLFGTEFQKKVCWEILVAGSEQGIEAGQVGLRLITKGERQTTVAREWYIGATSITDGRWHTVTITIDADAGEATCYIDGGFDGYQNGLPLSIGSAIWEQGAEVWLGVRPPIDVDAFGRSDSDGVESKMHIMDVFLWGKCLSEEEAASLHAAIGMADLDMIDLSDDNWQWTDSPPRVDGWDSDPADVDLYDRDDVDWDGQYSSGRKRRSGRDFVMSVDSFARRHRKPRMETQEDINQRMRSVELAVKEALSARGDKQFTDQEFPPNDRSLFVDTQNPPSKLQVVSEWMRPDSIVKENGSDSRPCLFSGDANPSDVCQGRLGDCWFLSAVAVLTEVSRISEVIITPEYNEEGIYTVRFCIQGEWVPVVIDDWIPCESPGKPAFATSRKLNELWVSMVEKAYAKLHGSYEALEGGLVQDALVDLTGGAGEEIDLRSAQAQIDLASGRLWSQLLRFKQEGFLLGAGSPSGSDVHVSSSGIVQGHAYSVLQVREVDGHRLVQIRNPWANEVEWNGPWSDSSPEWTDRMKHKLKHVPQSKEGIFWMSWQDFQIHFRSIYVCRVYPREMRYSVNGQWRGYSAGGCQDYSSWHQNPQFRLRATGSDASLPIHVFITLTQGVGFSRTTPGFRNYQSSHDSQLFYIGLRILKTRGRRAAYNIFLHESVGGTDYVNSREISCEMVLDPDPKGYTIVPTTIHPGEEAPFVLSVFTKASIVLEAL