wanglab/gogpt-training-data huggingface dataset:
Protein: Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (O22173)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity). During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp) (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Eukaryotic translation initiation factor isoform 4G-2
- Eukaryotic translation initiation factor 4E-1
- Eukaryotic translation initiation factor 4G
- Eukaryotic translation initiation factor 2 subunit alpha homolog
- Eukaryotic translation initiation factor isoform 4E
- Expressed protein family protein)
- DEAD-box ATP-dependent RNA helicase 52
- Eukaryotic translation initiation factor isoform 4G-1
- Protein IN CHLOROPLAST ATPASE BIOGENESIS
- Polyadenylate-binding protein-interacting protein 3
Sequence:
MAQVQAPSSHSPPPPAVVNDGAATASATPGIGVGGGGDGVTHGALCSLYVGDLDFNVTDSQLYDYFTEVCQVVSVRVCRDAATNTSLGYGYVNYSNTDDAEKAMQKLNYSYLNGKMIRITYSSRDSSARRSGVGNLFVKNLDKSVDNKTLHEAFSGCGTIVSCKVATDHMGQSRGYGFVQFDTEDSAKNAIEKLNGKVLNDKQIFVGPFLRKEERESAADKMKFTNVYVKNLSEATTDDELKTTFGQYGSISSAVVMRDGDGKSRCFGFVNFENPEDAARAVEALNGKKFDDKEWYVGKAQKKSERELELSRRYEQGSSDGGNKFDGLNLYVKNLDDTVTDEKLRELFAEFGTITSCKVMRDPSGTSKGSGFVAFSAASEASRVLNEMNGKMVGGKPLYVALAQRKEERRAKLQAQFSQMRPAFIPGVGPRMPIFTGGAPGLGQQIFYGQGPPPIIPHQPGFGYQPQLVPGMRPAFFGGPMMQPGQQGPRPGGRRSGDGPMRHQHQQPMPYMQPQMMPRGRGYRYPSGGRNMPDGPMPGGMVPVAYDMNVMPYSQPMSAGQLATSLANATPAQQRTLLGESLYPLVDQIESEHAAKVTGMLLEMDQTEVLHLLESPEALNAKVSEALDVLRNVNQPSSQGSEGNKSGSPSDLLASLSINDHL
Protein: Sperm acrosome-associated 4-like (A0A2R8RYF0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MNKIIFGSFVLALYLAVGHGLQCYECKLGFWDVCFTTKKTCDAGQLCFSGLGKAGGLVDVKTKGCLELSKCNKTESTTFPANSSTQIYQMTKTCCATDLCNSGHIHISAVNMAFTCITTVLMAKFLI
Protein: Vomeronasal 2, receptor 120 (A0A8V5KX69)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MLIFVSVLLFLNFPVASCEPINPGCSLGMADAIFQDGDVLVGVFLPLHAYLTSPQLYGPDIDTTMKQIHPNKYQYVIALNFAIEEINKNIHLLPNISLGYDMYSIVQYQATILEHSIRFLTGLKEAIPNYTCRKESKLIAVVTGTSWEFPSRISTILGLYKYPQLTFGPFDPMLSDHVKFPFIYQMAPEDTSLALGMVSLMVHFSWTWVGLIITENEKGIKFLSDLKREMKKNSVCAAFVQMLSLKYRYNWNDLLSTDPAIMGEMVKVFIVFADIDSTLVVIFKASGQVDPWRVWVTTSQWDIASSVRHFILDSFHGTLIFSQHHPEISAFKDFIQTVNPSKYPDDIFLSHIWKMYLNCPFSRVYCKTLKTCSSNGSLALLPWHRFDMDMSEESYHIYNAVYAVAHSLHEMLQEHADVQPVKSRKRLVFSPCRLHPFLKNIQFNNPSGDKVDLSHTGKLETKYDIFNFWNFPQGLGLKVKVGTFSSFLPRNKQFSLSDGMIEWGTKDKQTPLSVCSTSCAPGLMKSPQEGKASCCFDCHPCLENEISNETDSIQCIKCPDDQYANTEQTHCIPKAVTFLAYEDPLGMALACMALCFSALTALVLGVFVKHHETPIVKANNRTLSYILLISLILCFLCSLPFIGLPNMATCILQQMSFGVVFTIAVSTVLAKTVTVVLAFRSTVPGRRMRWILVSPNLIIPICTLIQMVLCAIWLGASAPFVDINAHNERGHITIMCNKGSATAFYCVLGYLGFLAMGTLTVAFWARNLPDIFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKVMVAVEVFSILASSAGLLGCIFVPKCYIILIRPKNGSFKGLRGTRVCK
Protein: Sodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3) (Q01959)
Organism: Homo sapiens (Human)
Function: Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:11343649, ECO:0000269|PubMed:15505207, ECO:0000269|PubMed:39112701}; Multi-pass membrane protein {ECO:0000269|PubMed:39112701, ECO:0000269|PubMed:39112703, ECO:0000269|PubMed:39112705}. Cell projection, neuron projection {ECO:0000250|UniProtKB:P23977}. Cell projection, axon {ECO:0000269|PubMed:17296554}. Note=Localizes to neurite tips in neuronal cells (By similarity). Colocalizes with SEPTIN4 at axon terminals, especially at the varicosities (By similarity). {ECO:0000250|UniProtKB:P23977, ECO:0000250|UniProtKB:Q61327}.
Interaction partners:
- D
- Alpha-synuclein
- Syntaxin-1A
- Synaptic vesicular amine transporter
- D
- Tyrosine 3-monooxygenase
- Calcium/calmodulin-dependent protein kinase type II subunit alpha
- Synaptogyrin-3
- Flotillin-1
- Protein kinase C beta type
Sequence:
MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV
Protein: Melanocortin receptor 4 (MC4-R) (P56450)
Organism: Mus musculus (Mouse)
Function: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P32245}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Pro-opiomelanocortin
- Agouti-related protein
- Leptin
- Guanine nucleotide-binding protein G
- Neutrophil gelatinase-associated lipocalin
- Pro-neuropeptide Y
- Alpha-ketoglutarate-dependent dioxygenase FTO
- Leptin receptor
- Melanocortin-2 receptor accessory protein 2
- Hypocretin neuropeptide precursor
Sequence:
MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTNMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELSSRY
Protein: Arginine--tRNA ligase (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) (O51540)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Isoleucine--tRNA ligase
- Methionine--tRNA ligase
- Glutamate--tRNA ligase
- Proline--tRNA ligase
- Valine--tRNA ligase
- Leucine--tRNA ligase
- Asparagine--tRNA ligase
- Translation initiation factor IF-2
- CTP synthase
- Serine--tRNA ligase
Sequence:
MNKSVKKKIKDEINVIVTNLALSNNIKLDNININIQKPPKSDLGDISILMFEIGKTLKLPIEIISEEIIKNLKTKYEIKAVGPYLNIKISRKEYINNTIQMVNTQKDTYGTSKYLDNKKIILEFSSPNTNKPLHVGHLRNDVIGESLSRILKAVGAKITKINLINDRGVHICKSMLAYKKFGNGITPEKAFKKGDHLIGDFYVKYNKYSQENENAEKEIQDLLLLWEQKDVSTIELWKKLNKWAIEGIKETYEITNTSFDKIYLESEIFKIGKNVVLEGLEKGFCYKREDGAICIDLPSDSDEKADTKVKQKVLIRSNGTSIYLTQDLGNIAVRTKEFNFEEMIYVVGSEQIQHFKSLFFVAEKLGLSKNKKLIHLSHGMVNLVDGKMKSREGNVIDADNLISNLIELIIPEMTQKIENKESAKKNALNIALGAIHYYLLKSAIHKDIVFNKKESLSFTGNSGPYIQYVGARINSILEKYKALSIPVMEKIDFELLKHEKEWEIIKIISELEENIINAAKDLNPSILTSYSYSLAKHFSTYYQEVKVIDTNNINLTAARIEFLKAILQTIKNCMYLLNIPYMLKM
Protein: Sec24b protein (Q6PFZ1)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
Sequence:
MSAPAGSPHPAAGARMPPKLGGAVSGLAPPQQNGPAQSPMQVPSGYGLPHQNYMVPSGHYSQGPGKMTSLPLDSQCDSYYSRPYTVPTQNSGTPSSANQPGAQQMYGRGPSAPHMGGSMPGSFQGIPASASHSYSSASQPYSSLGNRYSSPTTYSANASVASQGYPSTCSHYPISTVSNVVYPNVSYLSLPASEPYGQMFTSQSAPPPARPVKESYSGPSTALTYPSRPPPPPSQHQQQQQQQQQQQQQQQSHSGYSSLPWSGPALPPAQDSLIRNQMGSLATANSHPTNNENVQPPKSSSVVSTVLPGPSSTRMPPAPSHPVGPVPSAPPPPEQMQTKGMQYGDYGNNQASSTATPLSSASDDEEEQEEDEEAGVDSSSTTSSASPLPNSYDALEGGSYPDMHSSSASSPVPDHALEPSPTLAQALSAAPTPPAAQPAKVAKPFGYGYPALQPAYQNAAPPPMPAAHPSGPAYTGYPQHYPGVNQLSSGLGGLSLQSSPQPESLRPVNLTQEKNILPPTPIWAPVPNLSAELSKLNCSPDSFRCTLTSIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFLYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTVLCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPSMFINTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVHHLGPATDFYKKLALDC
Protein: LD35087p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Q9VWD5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Phosphatidylinositol 4-kinase beta
- GH05665p
- Nuclear inhibitor of protein phosphatase 1
Sequence:
MASGTSGTSSSETAQSTDMAPSSAEKWGFPLIELYRLAFTFYKRNSGKAIHLSYEDNLKLIAFKQQAALGPFNTSRAPALGVLDVIGRDRQQHWQLLGEITREQAMEGFVDLLDTMCSAFRPYIEAVRQDRDETLRKELRLMEEKKEARERQENAQQELLEEGYKEELQRRQLQDALNKQTYQQFKLYAEKQFPGNPEQQAVLIHQLQREHYHQYMQQLHLQNQNQNQNQNTEDKGHQEAEHVPGNNNNSSTDLPNAMEGLKLGEVETQQHQQLAEQQDGHVEQTLEGVGQEQHGEEEYDDYVMICPAKIWTRPDIEQFKTEVSAGDGDGVITIGHGDTVTVRVPTNMNGKCIFWEFATDSYDIGFGIYFEWAKPVTNEVTVHVSDSDEDEDCVDEDYLSTTEDLESGSLSQERGAVNNPTAAPKAPISIIVPIYRRECYNEVYVGSHSYPGEGVYLLKFDNSYSIWRNKTLYYRVYYER
Protein: Merozoite surface protein 11 (Q8IJ48)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Early transcribed membrane protein 4
Sequence:
MNKFLNIIFYIFLILNFSFFQSNATSKEIQKDEQKNLRNGSSINNNKNIENKNDNIETQYEASEYIEKQNDILNMYNDEKEKNNNNSLDTNVTKNTVIDNSNKFQSIEDNNVYNKGIFVGTGIKLNDSQTTSDNYKNERYQIDDEKLKYGGSFDTIFSGFVNLLTPSSPTQNDGSTGRNVPPPSEPNVDTPDPPTAPAPVKVPEDAKLSSSPRPEGPRANNRNENNQNTDPYNHYFAWEIGGGAPTYKPENNKNDNILLEHVKITSWDKEDIIKENEDTKREVQETEDTDETEDTDETEETEDMEDENEIVEDQLQENEDDEDNVNLEDINKNTRNDIFEEQIKLDSTQDDKAQKLISNEYKKTEEKKSLEDHVNLLFNFLQTNNQLDPSLKDLENELTFFLNNY
Protein: Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor) (Q63118)
Organism: Rattus norvegicus (Rat)
Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q16602}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q16602}.
Interaction partners:
- Receptor activity-modifying protein 2
- Receptor activity-modifying protein 3
- Receptor activity-modifying protein 1
- Pro-adrenomedullin
- Protein ADM2
- Islet amyloid polypeptide
- Calcitonin gene-related peptide 2
- Calcitonin
- DNA-directed RNA polymerase III subunit RPC9
- Calcitonin receptor
Sequence:
MMDKKCTLCFLFLLLLNMALIAAESEEGANQTDLGVTRNKIMTAQYECYQKIMQDPIQQGEGLYCNRTWDGWLCWNDVAAGTESMQYCPDYFQDFDPSEKVTKICDQDGNWFRHPDSNRTWTNYTLCNNSTHEKVKTALNLFYLTIIGHGLSIASLIISLIIFFYFKSLSCQRITLHKNLFFSFVCNSIVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLLPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWRPEGKVAEEVYDYVMHILMHYQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNGFSHSDALRSASYTVSTISDVQGYSHDCPTEHLNGKSIQDIENVALKPEKMYDLVM
Protein: Candida glabrata strain CBS138 chromosome A complete sequence (Q6FXY6)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Carbon catabolite-derepressing protein kinase
- Candida glabrata strain CBS138 chromosome D complete sequence
Sequence:
MSASASPEPHTPENNPSSVTNGSSTPNSGKSKAGKGDDAPRPHVCPICGRAFHRLEHQTRHMRTHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNPLPKGKRGRKKKPETILAEQRAREEAERNKNNPNYKPPSKSSLRRKTKRNTTFELGESTPSSSLTPPQQPNPQVQLPSSPMVGDETTNAPHSDGMTPIEPQRFLSSPPNHVRPVFGSANNSNSSSRIRLNALSSLQMMTPLSGRNSSSTMNLSQQASTTFLDNPDGSKNQNIILPRPKSLTDFASMHANGSSTNLTTLMQQPNMGNLMKRPNSVLSLNELVTQSGAGTHGYDTGNNSSLEEDDLKDPELENDQLRKKSKTATPTTGLSRSASGLNLSLKTKSLTNMQDMNKVNEKLLQYQKNVVSPQIAPQDGLPPLRSLHLQFPTG
Protein: Aluminum-activated malate transporter 6 (AtALMT6) (Q9SHM1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Malate transporter.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Tonoplast dicarboxylate transporter
- Putative aluminum-activated malate transporter 11
- GDSL esterase/lipase At1g33811
- GDSL esterase/lipase At5g18430
- Phosphoenolpyruvate carboxylase kinase 1
Sequence:
MGPFHQQSRERLLSQNEYSDMCFRKITNLCELGHSDRRRIFFAVKMGMALALCSVVIFLKEPLHDASKYSVWGILTVVVVFEYSVGATLVKGFNRAIGTVSAGGLALGIARLSVLSRDFEQTIIITCIFLAGFIASYSKLHPAMKPYEYAFRVFLLTFCIVLVSGNNTGDFFSTAYYRFLFIVVGATTCLVVNIFIFPIWAGEDLHKLVANNFKSVANSLEGCVNGYLQCVEYERVPSKILTYQTSDDPLYSGYRSAIQSTNQEESLLDFAIWEPPHGPYRTFNHPWKNYVKLSGAVRHCAFTVMAIHGCILSEIQAAPEKRQAFRHELQRVGNEGAKVLRLIGEKVEKMENLGPGEILNDVQRAAEELQMKIDSKSYLLVNSESWAATKEKAEAEEYEEEAHETKVIKSLSQIWDTNSSSNNQNPASGNDESQIWESTESMMLRNRETWPSVSFIGGSVVNETVYKVYESASSLSLATFASLLIEFVARLENLVNAFEELSTKADFRDPVPLNVVDQEGLWTTLMRLRRLRRYFGRS
Protein: Zinc finger BED domain-containing protein 3 (Q19787)
Organism: Caenorhabditis elegans
Function: Probable transcription factor. Involved in vulval organogenesis. During vulval development, may play a role in the regulation of cell cycle regulators such as cul-1. Positively modulates expression of homeobox protein lin-39, perhaps by binding to regulatory regions of the lin-39 gene, acting in the vulval lineage. Plays a role in larval molting.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Nematode cuticle collagen N-terminal domain-containing protein
- DUF281 domain-containing protein
- B lymphocyte-induced maturation protein 1 homolog
Sequence:
MQTQSPFGPLLGISSSLLPSPVTVAAAAAAANGHQGPVSLTTFPSAFAAFASQIRNNQLQSLLQSQIQALNGGMGSPGNGPGTPLSRNNYAHHHQQHQNQQHVGKIRGTTEYPLRKRVGGSTVKTAKVWRYFDELPTIEQAAECRICRKKIKATNSSTTGMIRHLRSCHVQEYQLVQEARQNSMIVKMEEKARAKLLREMNEKVITNGIENTPIVKKESQTESQKSPSASSSASDTASSASSSHFSTNPLIGLPAPVAIKPPAPPTPSNSILNLSQSQNQCQNQNPMFQSQNIKNEPTDVEEEDLEQKRSRDILHRPSDLGTKMFFSSPRTFNLTSAFSSITPLEDHKFQKKIEDDHKIHMQIALMLLLDQQPCQIIDRPGIRSLFKFVLPEYHMPSGDVFQATIVPQLLNQMKQQIEALVHNSSSLSSIPDQVMTSSSATSSYEDVSVNESQMAGPNVGDEEEEIMEEEVEEDENVEIEDDTSSASSSIDTDTCDAMASFIHFIGNDAFPHDELISLLSVVTNLFTYFSTRPHVQTHLQMTIIQPTSQPLVQQVQFVTSNLSIISDYIRQTPDMQLLPLAVNQEAMLEKLVDHIDQLV
Protein: Ubiquitin-conjugating enzyme E2, putative (EC 6.3.2.19) (Q57YD9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- propanoyl-CoA C-acyltransferase
- Nonspecific lipid-transfer protein, putative
- E3 ubiquitin-protein ligase TRIP12
- HECT-type E3 ubiquitin transferase
- Ubiquitin-protein ligase, putative
- Ubiquitin-protein ligase, putative
- Ubiquitin-conjugating enzyme, putative
- Polyubiquitin, putative
- Anaphase-promoting complex subunit 11
- Ubiquitin thioesterase
Sequence:
MCRVCRSLITVVMPCPISRLSKELKEVQRDPDNDVVLKLAESNNLFSWEAVLDGPPDTPYEGGSFCLRLQIPPDYPMVPPVAWFVTKVFHPNVNFDTGAVCLDILKSRWSPAWTISSVCRAIISLLTEPDARSPFNCDAGNLLRAGDVMGYNSLARMYAITEAGAPPFNDGE
Protein: Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein) (Q15334)
Organism: Homo sapiens (Human)
Function: Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane.
Subcellular location: Early endosome membrane {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Cell projection, axon {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12725730, ECO:0000269|PubMed:7542763}. Note=Localized to the lateral membrane during the polarization and formation cell-cell contacts. Enriched in developing axons (By similarity). {ECO:0000250}.
Interaction partners:
- Protein kinase C zeta type
- LLGL scribble cell polarity complex component 2
- Protein kinase C iota type
- Disks large homolog 4
- Disks large homolog 1
- Protein scribble homolog
- Partitioning defective 6 homolog beta
- Disks large homolog 3
- Ubiquitin-protein ligase E3A
- Disks large homolog 5
Sequence:
MMKFRFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGASAPLSLTRVTVVLLVAASDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLCWGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAAVTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQASYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSADTTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK
Protein: Zona pellucida-like domain-containing protein 1 (ZP domain-containing protein 1) (Cupulin) [Cleaved into: Zona pellucida-like domain-containing protein 1, secreted form] (C0H9B6)
Organism: Salmo salar (Atlantic salmon)
Function: Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ.
Subcellular location: [Zona pellucida-like domain-containing protein 1]: Cytoplasmic vesicle membrane {ECO:0000305|PubMed:25369234}; Single-pass type I membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Zona pellucida-like domain-containing protein 1, secreted form]: Secreted, extracellular space, extracellular matrix {ECO:0000305|PubMed:25369234}.
Interaction partners:
Sequence:
MEQICLIILLISKALSVGAQFNGYNCDANFHSRFPAERDISVYCGVQTITLKINFCPVLFSGYTDTDLALNGRHGDAHCRGFINNNTFPTVVLFSISLATLETCGNALVVSTAQGPNAYGNLSLVQIGNISGYIDTPDPPTIISYLPGLLYKFSCSYPLEYLVNNTQLASSAAAISVKDSNGTFVSTLSLLLYNDSSYVQQLSIPMAGLTLKTRVFAAVKATNLDRRWNVLMDYCYTTASGNPNDELRYDLFFSCDKDPQTTVFENGKSQMGRFAFEVFRFVKHKNQKMSTVFLHCVTKLCRADDCPMLMPICGSRKKRDVSERTESNSASGNAIITAGPIITRSDDTPMNNSQLAQLNSPVFRMNTVTSALISGIIILGVMSLCFFILSLTLLKGKRAPPTILSGARNPAFN
Protein: Vacuolar protein sorting-associated protein 45 (Q54GE3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with Golgi/endosomal vesicles and the trans-Golgi network. {ECO:0000250}.
Interaction partners:
- V-SNARE family protein
- Vesicle transport through interaction with t-SNAREs homolog 1A
- t-SNARE family protein
- t-SNARE family protein
- tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain domain-containing protein
- Tetratricopeptide-like helical domain-containing protein
- Sec1-like family protein
- Vacuolar protein sorting-associated protein 16 homolog
- t-SNARE coiled-coil homology domain-containing protein
- 7-fold repeat in clathrin and VPS proteins repeat-containing protein
Sequence:
MSGKQMDVIASIQEYINKILTNIQGMKVLVLDKETAGIVSMVYTQSEILQKEVFLFEKIENTKEKMLHMKGVYFIRPTQENIQSICDELKDPKFNKYHLFFTNTISKVSLDEIAKADEQDVVSEIQEYFGDFFAVNPDTFTLNLPGMLTKKSPRWQGDVGRVVDGLFSSLLALKKKPVIRYSSNSDTTRYLAEKITERMNRDRDLFDFRRQGEPLLLILDRKDDPITPLLHQWTYQAMIHELLTINNNRVSLAKAPGIKDELKEVVLSLDHDIFYKENLYKNFGDLGASIKDLVDQFQDKMNTNQNIQTIDDMKKFIENYPNFQKFSTTVSKHVSLMDELNRLISLDNLMEVSEVQQELACNHDHNSIYNHVLEIVNDSKYTDRDKLVLVLLYSIRYEDGRVWELKEKLSSIGIPPKEIGLIDTLRGYAGASLREGDLLGTKNIFSFARSVVKRGLQGVSNIYTQHKPLLHDILDSILKNKLKETSYPYLSTTQSRERPQDVIIFMVGGITYEEALTVYTFNSLNTGVCRVVLGGTSILNREQFLEDLSSTQISNPSSSSGRR
Protein: Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) (Q5XIT1)
Organism: Rattus norvegicus (Rat)
Function: Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9UPY8}. Note=Associated with the microtubule network. Detected at the plus end of microtubules. {ECO:0000250|UniProtKB:Q9UPY8}.
Interaction partners:
- Dynactin subunit 1
- Drebrin
- Microtubule-associated protein RP/EB family member 1
- CAP-Gly domain-containing linker protein 1
- Ankyrin-3
- CAP-Gly domain-containing linker protein 2
- SRC kinase signaling inhibitor 1
- Cytoskeleton-associated protein 5
- Src substrate cortactin
- Hematopoietic lineage cell-specific protein
Sequence:
MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHEADAQILELNQQLLDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY
Protein: Prickle-like protein 1-A (XPk-A) (XpkA) (Q90Z06)
Organism: Xenopus laevis (African clawed frog)
Function: Acts in a planar cell polarity (PCP) complex; polarization along the apical/basal axis of epithelial cells. Regulates the polarized assembly of fibronectrin on the surface of the mesoderm during gastrulation. Essential for gastrulation cell movements, cooperating with dvl2/dsh to activate jnk. Acts together with tes to control axial elongation.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
Sequence:
MPLEMDQKVNKLTFGCQRSSTSDDDSGCAMEEYTWVPPGLRLEQVQLYFACLPEEKIPYVNSVGEKYRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQMFSAQRKKEALGRGNIKMLSRAVMHATCEKCGEKINGGEVAIFVSRAGPGVCWHPSCFVCSTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMNHFCCYECETVLGGQRYIMKDGRPFCCGCFESHYAEYCESCGEHIGVDHAQMTYDGQHWHATETCFSCAQCKVSLLGCPFLPKKGRIYCCKACSLGEDVHASDSSDSAFQSARSRESRRSVRMGKSSRSADQCRQSLLLSPAVNYKFPGMFGNADDTLSRKMDDLSMSRQGAGFDNDTWKARDEQETAEDHEEWAEHDDYMTQLLLKFGEKGLFQQPPEDNRSNDHWMSENIKGKNDLQRNNRNQSLASKKYQSDMYWAQSQDGLGDSAYGSHPGPASSRKLQELDMDHGASGYMHEKMPWYKRSLECLSNNLKPQNENICDSMDSLALSNITGASVDAESKSRPSLFSYQNFQELNTRDFDKMSNMGTLNSSMLNRSTESLKSLNSEICQEKPPPEEKPMHTSALKRSKSQTRPQVKFSDDVIDNGDYSSIEIRRPPMSERSRRRVYNSEEQSQRPHHHHHHRRRKSRKSRSENALHLATDSKSSGKERKRSYTAEDYERLFHNKSAHEVQAYIQNADLFGQYSNAASNVGLPSQVVDKFLGLYGEDEDSWCSTCSSSSSDSEEEGYFLGQPIPKPRPQRYQYFSDDLCSPTNALSSSQFSQRTSKSKKKKGHKGKNCIIS
Protein: Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic (AGPR) (EC 1.2.1.38) (N-acetyl-glutamate semialdehyde dehydrogenase) (NAGSA dehydrogenase) (Q93Z70)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Argininosuccinate lyase, chloroplastic
- Acetylglutamate kinase, chloroplastic
- Arginine biosynthesis bifunctional protein ArgJ
- Argininosuccinate synthase, chloroplastic
- Acetylornithine aminotransferase, chloroplastic/mitochondrial
- Ornithine transcarbamylase, chloroplastic
- Probable amino-acid acetyltransferase NAGS1, chloroplastic
- Probable amino-acid acetyltransferase NAGS2, chloroplastic
- Ornithine aminotransferase, mitochondrial
- At2g22905
Sequence:
MSTASAFSSIQGCWFKGERKIRVADKRAKRLTLGSHVASPSSMSFRVSASSSVKPEKDIRIGLLGASGYTGAEIVRLLANHPHFQVTLMTADRKAGQSMESVFPHLRAQKLPTLVSVKDADFSTVDAVFCCLPHGTTQEIIKELPTALKIVDLSADFRLRNIAEYEEWYGQPHKAVELQKEVVYGLTEILREDIKKARLVANPGCYPTTIQLPLVPLLKANLIKHENIIIDAKSGVSGAGRGAKEANLYSEIAEGISSYGVTRHRHVPEIEQGLSDVAQSKVTVSFTPHLMPMIRGMQSTIYVEMAPGVRTEDLHQQLKTSYEDEEFVKVLDEGVVPRTHNVRGSNYCHMSVFPDRIPGRAIIISVIDNLVKGASGQALQNLNIMLGYPETTGLLHQPLFP