wanglab/gogpt-training-data huggingface dataset:
Protein: Ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (EC 3.6.1.-) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2) (Q9Y5L3)
Organism: Homo sapiens (Human)
Function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.
Subcellular location: [Isoform Long]: Cell membrane; Multi-pass membrane protein.; SUBCELLULAR LOCATION: [Isoform Short]: Endoplasmic reticulum membrane; Multi-pass membrane protein.; SUBCELLULAR LOCATION: [Isoform gamma]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- Cancer-related nucleoside-triphosphatase
- Ectonucleoside triphosphate diphosphohydrolase 1
- Adenylate kinase isoenzyme 1
- Ribonucleoside-diphosphate reductase large subunit
- Ribonucleoside-diphosphate reductase subunit M2
- Nucleoside diphosphate kinase 3
- Ectonucleoside triphosphate diphosphohydrolase 8
- Adenylate kinase isoenzyme 5
- Ribonucleoside-diphosphate reductase subunit M2 B
- Ectonucleoside triphosphate diphosphohydrolase 3
Sequence:
MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
Protein: Synaptic vesicle glycoprotein 2C (Synaptic vesicle protein 2C) (Q9Z2I6)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:10625067, ECO:0000269|PubMed:16306227}; Multi-pass membrane protein {ECO:0000269|PubMed:10625067, ECO:0000269|PubMed:16306227}. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.
Interaction partners:
- Synaptic vesicle glycoprotein 2A
- Laminin subunit gamma-2
- Pancreatic secretory granule membrane major glycoprotein GP2
- Laminin subunit gamma-1
- Laminin subunit beta-1
- Laminin subunit gamma-3
Sequence:
MEDSYKDRTSLMKGAKDIAKEVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEDDDDDYYPPGETYSGEANDDEGSSEATEGHDEEDEIYEGEYQGIPSTNQGKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLLCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQVHTGMEYDNGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFENTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM
Protein: Large ribosomal subunit protein mL45 (39S ribosomal protein L45, mitochondrial) (L45mt) (MRP-L45) (Q9BRJ2)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042, ECO:0000269|PubMed:33602856}.
Interaction partners:
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL39
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein mL37
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein uL11m
- Large ribosomal subunit protein mL65
- Large ribosomal subunit protein mL50
- Large ribosomal subunit protein mL64
Sequence:
MAAPIPQGFSCLSRFLGWWFRQPVLVTQSAAIVPVRTKKRFTPPIYQPKFKTEKEFMQHARKAGLVIPPEKSDRSIHLACTAGIFDAYVPPEGDARISSLSKEGLIERTERMKKTMASQVSIRRIKDYDANFKIKDFPEKAKDIFIEAHLCLNNSDHDRLHTLVTEHCFPDMTWDIKYKTVRWSFVESLEPSHVVQVRCSSMMNQGNVYGQITVRMHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFEKQLTNPYGSWRMHTKIVPPWAPPKQPILKTVMIPGPQLKPEEEYEEAQGEAQKPQLA
Protein: Secretory carrier-associated membrane protein 3 (AtSC3) (Secretory carrier membrane protein 3) (Q9M5P2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably involved in membrane trafficking.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15060130}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- F-box protein At3g17320
- Protein YIP
Sequence:
MANRYDPNPFAEEEEVNPFANARGVPPASNSRLSPLPPEPVGFDYGRTVDIPLDRAGTQDLKKKEKELQAKEAELKRREQDLKRKEDAAARAGIVIEVKNWPPFFPLIHHDIANEIPVHLQRLQYVTFATYLGLVLCLFWNIIAVTTAWIKGEGVTIWLLALIYFIAGVPGGYVLWYRPLYRAFRTDSALSFGWFFLFYMLHIAFCVFAAVAPPVVFKGKSLAGILPAIDVLSGQAIVGIFYFIGFAFFCLESVVSIWVIQQVYMYFRGSGKQDQMRREAARGALRAAV
Protein: MHC class Ib antigen (Q6SY93)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
SHSLRYFETAVSQPGLGEPPVISVGFVDDTQFVRYDSDEENPKYEPRARWMEREGPEYWERETQRAKGNEQWSRVNLGTALRYYNQSEGGSHTMQRLSGCAVGSDGSLLRGYDQYAYDGRDYIALNEDLKTWTAADTAAQITQSKWDQAGEAERSRAYLEGKCVEWLLRYLELGKETLLRSDPPKAHMTLHPRPEGDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWASVVVPLGKEQSYTCHVEHEGLPEPLTLRWEPPPSTDFNVRIIAVLVVLGAVAIIGPVVAVVMKRRRNTGGTGGDYAPASGKTSPNSCDVSLPDCKA
Protein: Dual specificity phosphatase Cdc25 (EC 3.1.3.48) (Arath;CDC25) (Arsenate reductase) (AtASR) (Arsenate reductase 2) (EC 1.20.4.1) (Sulfurtransferase 5) (AtStr5) (Q8GY31)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Tyrosine protein phosphatase that dephosphorylates CDK complex and activate its kinase activity in vitro.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Wee1-like protein kinase
- Probable inactive protein kinase At3g63330
- Cyclin-dependent kinase A-1
- Cyclin-dependent kinase B2-2
- F10B6.17
- Cyclin-dependent kinase B1-1
- Cyclin-dependent kinase B1-2
- Cyclin-dependent kinase B2-1
- Cyclin-dependent kinase F-1
- Origin of replication complex subunit 5
Sequence:
MGRSIFSFFTKKKKMAMARSISYITSTQLLPLHRRPNIAIIDVRDEERNYDGHIAGSLHYASGSFDDKISHLVQNVKDKDTLVFHCALSQVRGPTCARRLVNYLDEKKEDTGIKNIMILERGFNGWEASGKPVCRCAEVPCKGDCA
Protein: Protein shisa-5 (Putative NF-kappa-B-activating protein 120) (Scotin) (Q8N114)
Organism: Homo sapiens (Human)
Function: Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12135983}; Single-pass type I membrane protein {ECO:0000269|PubMed:12135983}. Nucleus membrane {ECO:0000269|PubMed:12135983}.
Interaction partners:
Sequence:
MTAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDVLKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSVVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL
Protein: Hemagglutinin (Q6DQ33)
Organism: Influenza A virus (strain A/Vietnam/1203/2004 H5N1)
Subcellular location: Host apical cell membrane {ECO:0000256|ARBA:ARBA00004310}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004310}.
Interaction partners:
Sequence:
MEKIVLLFAIVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKKHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKANPVNDLCYPGDFNDYEELKHLLSRINHFEKIQIIPKSSWSSHEASLGVSSACPYQGKSSFFRNVVWLIKKNSTYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTYISVGTSTLNQRLVPRIATRSKVNGQSGRMEFFWTILKPNDAINFESNGNFIAPEYAYKIVKKGDSTIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSPQRERRRKKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYPQYSEEARLKREEISGVKLESIGIYQILSIYSTVASSLALAIMVAGLSLWMCSNGSLQCR
Protein: ESX-1 secretion-associated protein EspA (P9WJE1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Required for secretion of EsxA (ESAT-6) and EsxB (CFP-10) and for virulence. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm.
Subcellular location: Secreted {ECO:0000269|PubMed:16030141, ECO:0000269|PubMed:20585630, ECO:0000269|PubMed:22155774}. Note=Secreted via the ESX-1 / type VII secretion system (T7SS) (PubMed:16030141). Secretion of EspA, EsxA and EsxB is mutually dependent (PubMed:16030141). {ECO:0000269|PubMed:16030141}.
Interaction partners:
- ESX-1 secretion-associated protein EspC
- ESX-1 secretion-associated protein EspD
- ESAT-6-like protein EsxB
- 6 kDa early secretory antigenic target
- Transposase
- ESX-1 secretion-associated protein EspB
- Nucleoid-associated protein EspR
- Uncharacterized protein
- ESX-1 secretion system protein EccCb1
- ESX-1 secretion system protein EccCa1
Sequence:
MSRAFIIDPTISAIDGLYDLLGIGIPNQGGILYSSLEYFEKALEELAAAFPGDGWLGSAADKYAGKNRNHVNFFQELADLDRQLISLIHDQANAVQTTRDILEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGALAYLVVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGTLGEVWEFITNALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATSGLSQVTGLFGAAGLSASSGLAHADSLASSASLPALAGIGGGSGFGGLPSLAQVHAASTRQALRPRADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMGGMHPSSGASKGTTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV
Protein: Photosystem I reaction center subunit II-1, chloroplastic (Photosystem I 20 kDa subunit 1) (PSI-D1) (Q9S7H1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center. PSAD may encode the ferredoxin-docking protein.
Subcellular location: Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Interaction partners:
- Photosystem I reaction center subunit IV B, chloroplastic
- Photosystem I reaction center subunit IV A, chloroplastic
- Photosystem I reaction center subunit III, chloroplastic
- Photosystem I reaction center subunit XI, chloroplastic
- Photosystem I reaction center subunit psaK, chloroplastic
- Photosystem I P700 chlorophyll a apoprotein A1
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I chlorophyll a/b-binding protein 3-1, chloroplastic
- Photosystem I reaction center subunit VI-1, chloroplastic
- Photosystem I reaction center subunit V, chloroplastic
Sequence:
MATQAAGIFNSAITTAATSGVKKLHFFSTTHRPKSLSFTKTAIRAEKTDSSAAAAAAPATKEAPVGFTPPQLDPNTPSPIFAGSTGGLLRKAQVEEFYVITWNSPKEQIFEMPTGGAAIMREGPNLLKLARKEQCLALGTRLRSKYKITYQFYRVFPNGEVQYLHPKDGVYPEKANPGREGVGLNMRSIGKNVSPIEVKFTGKQSYDL
Protein: Outer plastidial membrane protein porin (Voltage-dependent anion-selective channel protein) (VDAC) (P42054)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).
Subcellular location: Plastid outer membrane. Note=Found in non-photosynthetic root plastids only.
Interaction partners:
Sequence:
MVKGPGLYTDIGKKARDLLYKDYHSDKKFTISTYSPTGVAITSSGTKKGELFLGDVNTQLKNKNITTDIKVDTNSNLFTTITVNEPAPGVKAILSFKVPEQTSGKVELQYLHEYAGISSSVGLKANPIVNFSSVIGTNALAFGADISFDTKLGELTKSNAAVNFVKDDLIGSLTLNEKGDLLSASYYHAINPLSNTAVGVDISHRFSTKENTFTLGTQHALDPLTTVKGRVTNSGKASALIQHEWRPKSLITISSEVDTKAIEKSAKIGLSLALKP
Protein: Transcription factor MYB64 (Myb-related protein 64) (AtMYB64) (Protein UAS-TAGGED ROOT PATTERNING 10) (Q9FY60)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor required for female gametophyte fertility. Acts redundantly with MYB119 to initiate the FG5 transition during female gametophyte development. The FG5 transition represents the switch between free nuclear divisions and cellularization-differentiation in female gametophyte, and occurs during developmental stage FG5.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:24068955}.
Interaction partners:
- C2H2 and C2HC zinc fingers superfamily protein
- C2H2 and C2HC zinc fingers superfamily protein
- Nuclear transcription factor Y subunit C-5
Sequence:
MEEQKIQEKSLAHGAAPPLTAVERFLNGQKNEALCFKKQERSIDRPIVKTTRAIEIRNENKENMMFGPRKEKNLAVIGEIVVKGAAKDYTCKDITKKQPYKNIIKGQWTADEDRKLIKLVMQHGERKWAVISEKLEGRAGKQCRERWHNHLRPDIKKDSWSEEEERLLVEAHTRIGNKWAEIAKLIQGRTENSIKNHWNATKRRQNSKRKHKRSKNADSNSDIDDLSPSAKRPRILEDYIKNIENNDKNNGENIMTTSGNNVLSTSNYDQFNSEDSTSSLLDDPYDEELVFLKNIFENHSLENINLSQGTEITQSSSSGFMIENPKPKPNLYNNTFGTHLGAMVTEPANSSHLASDIYLSDLLNGTASSSSSLTFLSSNNNEHAGENELLLPQANSTSERREMDLIEMLSGSTQGSNIWFPLF
Protein: Ribosome binding protein 1 (A0A087WU26)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
Sequence:
MEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKEDGSSSKEGTSV
Protein: snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE-binding factor subunit gamma) (PTF subunit gamma) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Q16533)
Organism: Homo sapiens (Human)
Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Subcellular location: Nucleus.
Interaction partners:
- snRNA-activating protein complex subunit 2
- snRNA-activating protein complex subunit 5
- snRNA-activating protein complex subunit 3
- snRNA-activating protein complex subunit 4
- TATA-box-binding protein
- Transcription initiation factor IIB
- Transcription initiation factor IIA subunit 2
- Transcription initiation factor IIA subunit 1
- Transcription factor TFIIIB component B'' homolog
- Transcription factor IIIB 50 kDa subunit
Sequence:
MGTPPGLQTDCEALLSRFQETDSVRFEDFTELWRNMKFGTIFCGRMRNLEKNMFTKEALALAWRYFLPPYTFQIRVGALYLLYGLYNTQLCQPKQKIRVALKDWDEVLKFQQDLVNAQHFDAAYIFRKLRLDRAFHFTAMPKLLSYRMKKKIHRAEVTEEFKDPSDRVMKLITSDVLEEMLNVHDHYQNMKHVISVDKSKPDKALSLIKDDFFDNIKNIVLEHQQWHKDRKNPSLKSKTNDGEEKMEGNSQETERCERAESLAKIKSKAFSVVIQASKSRRHRQVKLDSSDSDSASGQGQVKATRKKEKKERLKPAGRKMSLRNKGNVQNIHKEDKPLSLSMPVITEEEENESLSGTEFTASKKRRKH
Protein: Beta-glucosidase 44 (AtBGLU44) (EC 3.2.1.21) (Q9LV33)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Hydrolyzes p-nitrophenyl beta-D-glucoside, p-nitrophenyl beta-D-mannoside, cellobiose, 4-methylumbelliferyl-beta-D-glucoside, laminarin, amygdalin, esculin and gentiobiose.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Glycosyl hydrolase family protein
- Endoglucanase 9
- At3g47000
- Beta-D-glucan exohydrolase-like protein
- Beta-D-glucan exohydrolase-like protein
- Glycosyl hydrolase family protein
- Glycosyl hydrolase family protein
- beta-glucosidase
- (R)-mandelonitrile lyase-like (Hydroxynitrile lyase-like) ((R)-oxynitrilase-like)
- Endoglucanase 8
Sequence:
MRHLSSPPWPLLLLLLLSSFTSGESSLSAEKNKLHTGGLSRQSFPKGFVFGTATSAYQVEGETHQDGRGPSIWDAFVKIPGKIAKNATAEITVDQYHRYKEDVDLMKKLNFDAYRFSISWSRIFPEGSGKVNWKGVAYYNRLIDYMVQKGITPYANLYHYDLPLALENKYKGLLGRQVVKDFADYAEFCYKTFGDRVKNWMTFNEPRVVAALGYDNGIFAPGRCSKAFGNCTEGNSATEPYIVTHHLILAHAAAVQRYRKYYQAKQKGRVGILLDFVWYEPLTRSKADNLAAQRARDFHIGWFIHPLVYGEYPKTMQNIVKERLPKFTEKEVKMVKGSIDFVGINQYTTYYMSEPHPTTKPKDLGYQQDWNVEFGFAKLGKPIGPRAYSSWLYNVPWGMYKALMYMKERYGNPTMILSENGMDDPGNVTLAQGLHDTTRIKYYKDYLTNLKKARDDGANVVGYFAWSLLDNFEWLSGYTSRFGIVYVDYKTLKRYPKMSAQWFKQLLKRNNK
Protein: Protein PAL1 (Pears and lemons protein 1) (Q05518)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the early step of endocytosis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22190733}; Peripheral membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22190733}. Note=Localizes to the cell periphery and the bud neck. Found at endocytic sites at the cell periphery during the early stages of endocytosis.
Interaction partners:
- EH domain-containing and endocytosis protein 1
- Clathrin coat assembly protein AP180A
- Suppressor of yeast profilin deletion
- Clathrin coat assembly protein AP180B
Sequence:
MENRNSSTSSRPFSVNNPFRNATVDSSINQYKNDSQFQEWAKNQSRTNSFDMPQLNTRTSSQLSFPNIPEDEPQRNADQQGAFYSGLESFSSGSLSPPSRPLSSKNPFLDDVSSATDFRRSPPPVSRNKNHPTAKEEKEQLRQRYLEESDVSTVGNTRENTDLPPSYEEITSTNGSRRAYPKEKVSRPSSHREHSNSGTYISRRSSSHHHREASSSSTPSKKGKRKSKVIVPKNVDTIDKLDVTGLFGGSFHHDGPFDAVTPHRNKNNKAAPVLAFPVDGPNSTIGGASTKKSALDEVFGRDDTDDSDIYQYSSQTLRRGGDTQDAIKANVGNVQQMDAKNKTELVHGPVTAGLGSSTFLDGAPASSAAIRNDIKAHSYHNRNGGLQRNKSLSQRLGLGGSGDSNAPMTGVRRNLSLSRDNYDVGHSNEGVRRSKTVNSPNRTHKSNYTTDFDGQDDHNEDEEDVYLGVRYNEPNMKKKSTGSKLLSRVKSLKVGRKSQ
Protein: non-specific protein-tyrosine kinase (EC 2.7.10.2) (A0A2R8RR02)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cell projection {ECO:0000256|ARBA:ARBA00004316}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MESSGCSPFPLCWARGACVYSYPPPLPKYDGQLAPTKAMAAAYLDPNPTHALNQGVKPRFSSGMERTAAALERVLKIFHYFESSSEPCSWASNIRHGDSTDVRGIIQKILDIHKVRCVSCFGLRLSHLRTGEIHWLHPDMGVSHVRERYEHSHPQDDWRYELRIRYLPKGFLNQFTEDQPTLNYFYHQVKSDYMMEIADQVDQDIALKLGCLEIRRFFRDMPGNALDKKSNYELLEKDVGLRRFFPKSLLDSVKAKSLRKLIQQTFKQFANLNNEQCMLKFFEILSPIYRFDKECFKCALGSSWVISVELAIGPEEGISYLTDKGSNPTHLANFTQVQTIQFEERERKGMLLLDVAGAPEPLTVTTTTLNTAENMADLIDGYCRLVSGTSSSFIVRVQKEGERALPSIPKAPKSANHEKRLQGVRAKAISISDDIGGDETDDYAEIIDEEDTYTMPSKYYGLDEARDYEIQRDRIELGRCIGEGQFGDVHQGIYICPDTPALSVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQIRKYNLDLASLILFSYQLSTALAYLESKRFVHRDIAARNVLVSSVDCVKLGDFGLSRYMEDSSYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIENGERLAMPPNCPPTLYSLMTKCWAYDPSKRPRFTELKGQLSTILAEEKAQQEERSRMEMRRQVPVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMGQHNHYQMAGHSGPHGLLSVPGGLYPPQATVTGLDPHDSWNHRRVAQDHMWNPSMEDGVALRGGLSQLMEEQLILQQQQMEDDQRWLEHEERLLKPDGRSSRGSTERDDGSLQGPTGNQHIYQPIGKAEHAAPPKKPPRPGAPSHAAGVSGLNPTESYNEGVKIQPQEINPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPAHTHREIEMAQKLLNSDLAELINKMKLAQQYVMTSLQQDYKKQMLTAAHALAVDAKNLLDVIDQARLKLLGQARPH
Protein: IP10788p (Natalisin, isoform C) (Q4V427)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRLTLAWLSLCLAIYCGGGHGHGNVVLSLPPSLIATATKAALSHQRQQKQQQQHQKKDARVLFDSPADALRDMMHNGNGNGNGPMDSGKFSLSDVEQPAAQRSEDFNRNAYDLGARQSAPQEIAMGMELGMGLGLGPNNYRTTPPHRYWGQRCQGRSGGSGTSKCPQEYYRTMLAARNKEALSRLHMQLSSMQDSDSGASSSSDSEEEHVDDEEQSNNEVFMLLTGEQDLMKFLHWAMQVLYPIERPLGNLSDGAAENYYPGMFLWKKLNLSGHLEPPLIVDEPQYVLVRREKLFDGYQFGDMSKENDPFIPPRGRKHSGSLDLDALMNRYEPFVPNRGKRDKVKDLFKYDDLFYPHRGKKHRNLFQVDDPFFATRGKKLQLRDLYNADDPFVPNRGKRHLTASAGKLGETMAGGGKWPDDSNNYWPLRMSTHKINGYDQSVRPSLSVEDAAASLASWRLPANRLHSTRSMSADLRQQLLLPHVRFIGNPNMRQQQQQQQQHQVKTSSWQAEERLRRSILAPGESNDAHETQLTLSHPANPHLVTDTDNLNI
Protein: Zinc-finger protein ZPR1, putative (Q57ZU8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Retrotransposon hot spot
- Zinc-finger domain-containing protein
- Retrotransposon hot spot
Sequence:
MAETPKEIPPDEAPLRAAMGEVQEDVAHNTEGDEESTANCIRTELGEMNEIESRCPRCGGNGTTRLMITNIPHFKEVIVSSFECPHCGERNNEVTFGGEFGPKSVRYELEVKSKKDLDRQVVKSEYATIRIPELDLEIPRESQRGVLNTVEGFLEQTESGLQLQQPLRRIQHPELYEKLETFCEKVRQYRTGDVPFTFIIDDPAGNSYVEAYYDYYHPTIDPQLTRYEKERTNIDRQLLGLTIEYNTQRTDAEQREVQEGQFDDVVRMETECSACKKPGFINIQQVNIPYFKETVIMAFRCDFCGYKSNEVKSGGAVAEKGLKITLEVKSESDLKRDVLKSDSTTLLIPEVALELAPGTLGGFFSTVEGTLMMVRDQLKSLPQAQFAKGDAAATDPEAKTLTTFVKELEHLLELKRPFTFILDDPLANVYIQNPREHLPPPENEDPQLTKTYYTRTFEQDEELGFHQMNVN
Protein: Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog) (Q9H7B2)
Organism: Homo sapiens (Human)
Function: Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:19170763}. Note=Associated with the nucleolus in an RNA-dependent manner.
Interaction partners:
- GTP-binding protein 4
- Probable ribosome biogenesis protein RLP24
- mRNA turnover protein 4 homolog
- Ribosome biogenesis protein NSA2 homolog
- Ribosome biogenesis regulatory protein homolog
- Probable rRNA-processing protein EBP2
- Nucleolar GTP-binding protein 2
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- Nucleolar complex protein 2 homolog
- Large ribosomal subunit protein uL5
Sequence:
MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKSKRIKKN
Protein: Inter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP) (P19827)
Organism: Homo sapiens (Human)
Function: May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Subcellular location: Secreted.
Interaction partners:
- Protein AMBP
- Inter-alpha-trypsin inhibitor heavy chain H2
- Inter-alpha-trypsin inhibitor heavy chain H3
- Alpha-2-HS-glycoprotein
Sequence:
MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF