wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquinol-cytochrome c reductase complex assembly factor 2 (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19) (Q9CQY6)
Organism: Mus musculus (Mouse)
Function: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability.
Subcellular location: Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}. Mitochondrion {ECO:0000269|PubMed:22363741}. Mitochondrion intermembrane space {ECO:0000269|PubMed:22363741}. Mitochondrion matrix {ECO:0000269|PubMed:22363741}. Mitochondrion inner membrane {ECO:0000269|PubMed:22363741}. Note=Predominantly expressed in the mitochondrial inner membrane.
Interaction partners:
- Ubiquinol-cytochrome c reductase complex assembly factor 1
- Ubiquinol-cytochrome-c reductase complex assembly factor 3
- N-alpha-acetyltransferase 38, NatC auxiliary subunit
- Cytochrome b-c1 complex subunit 10
Sequence:
MAALRYRRFLKLCEEWPVDETKRGRDLGAYLRQRVAQAFREGENTQIAEPEACDQMYESLARLHSNYYKHKYPRPRDTSFSGLSVEEYKLILSTDTLEEFQEMNKSMWKKLQEKFAPTRPEEKHKAWTRVLSRPRT
Protein: LD10519p (Q86M56)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNFVLSVLLIAILKDKYDYWLPSRTGCQTLAANIWSDKTTAQNEPINLTNANAPIKNAKNLNSTITNVAAFDTKLNHLLVDTITGRVFVGGVNRLYQLSPDLELSETVKTGPQNDSVECSILDCPLNAVRSPTDNYNKVLLIDRATSRLIACGSLFQGTCTVRNLQNVSIIEHEVPDAVVANDANSSTVAFIAPGPPQHPVTNVMYVGVTYTNNSPYRSEIPAVASRSLEKTKMFQIASSAVTTGTRTFINSYARETYFVNYVYGFSSERFSYFLTTQLKHSHHSSPKEYITKLVRICQEDSNYYSYTEIPVECISDAQGGTKFNLVQAGFLGKPSSDLAQSLGISIQDDVLFAVFSKGEGNTPTNNSALCIYSLKSIRRKFMQNIKSCFNGSGMRGLDFISPSMPCVLTSGEQALLGE
Protein: Nitric oxide synthase (EC 1.14.13.39) (A9JNR5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
Sequence:
MGNQVTHKSELLQQMKPDMQWENKVKQCPFSKQLKNYQDSSCHQDVLHHRAVKSHICSSKICEGSIMTPKSLTRCPMTTLHCPDDILVQAVDFINQYYKSVKNSKIEEHLSRVEEVAMEIDATGSYQLTTKELEFGAKQAWRNAPRCIGRIQWANLQLFDARKCQTAEDMFQMLCDHIQFATNGGNLRSAITVFPQRADGQHDFRVWNSQLIRYAGYKMTDGTILGDPASVDFTEICIQLGWTPKYGLFDVLPLLLQANGEDPQLFEIPKDLILEVPMEHPQYEWFEDLNLRWYALPAVSNMLLEIGGLEFPACPFNGWYMGTEIGVRNFCDTQRYSVLEHVGRQMSLETQNLSSLWKDQALVAINVAVMHSYQKNKVTITDHHSASESFMQYMEMEVRLRGGCPADWVWLVPPMSGSLTPVFHQEMLNYILSPFFYYQPEAWLTHKWKDMKRKARRCTISFKGLIRVVLFSQVLIKLAMAKRVCCTVLYATETGKSQTFAKKLNGIMNCCFSSRVVCMEDYNVSELEKESLLIVVTSTLGNGDCPGNGESFKKQLLSLKTLRNKVRYCVFGLGSRMYPHFCAFAHALDAMFATLGAIRVSSTGEGDELKGQEESFSSWACTAFKDACKEFNVQGQLPGTDCLVDSWDSQRYRVQNDSCTVDRITALSTLHSKAVVPMKLKRRQNLQSAKSSCATILVELEMEGNTEPLNFTPGDHVGIFAGNSPGLVAGILKRLPNANPINQSLQLEFLSAHADGERWQRDERIPPCSFAQALTYYLDVTSPPSQSLLRKLSKIARQEDHRQHLLALASDFQVYTTWKDFFKPTFLEVLEEFPSLELPAAFPLSQLPLLKPRLYSISSSPDLHPQELHLTVAVISYYTQEGKGPLHFGLCSNWLNTIKEGDTVPCFLHSSDWFHLPSDPNAPCILVGVGSGIAPFRSFWQQQFHDMNKTGLKGNPMTLVFGCRSSDTDHLYKEEILDMRDNGTLSSITTAYSRQTGQAKVYVQDILREQLNDKIFEVLHHNSGHVYVCGGVNMACDVAATVKEILVNQMGITVAQAEEYLSRLKNEKRYHEDIFGY
Protein: GTPase IMAP family member 4 (Immunity-associated nucleotide 1 protein) (IAN-1) (hIAN1) (Immunity-associated protein 4) (Q9NUV9)
Organism: Homo sapiens (Human)
Function: During thymocyte development, may play a role in the regulation of apoptosis (By similarity). GTPase which exhibits a higher affinity for GDP than for GTP.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:23454188}.
Interaction partners:
- GTPase IMAP family member 7
- GTPase IMAP family member 8
- GTPase IMAP family member 6
- GTPase IMAP family member 5
- GTPase IMAP family member 1
Sequence:
MAAQYGSMSFNPSTPGASYGPGRQEPRNSQLRIVLVGKTGAGKSATGNSILGRKVFHSGTAAKSITKKCEKRSSSWKETELVVVDTPGIFDTEVPNAETSKEIIRCILLTSPGPHALLLVVPLGRYTEEEHKATEKILKMFGERARSFMILIFTRKDDLGDTNLHDYLREAPEDIQDLMDIFGDRYCALNNKATGAEQEAQRAQLLGLIQRVVRENKEGCYTNRMYQRAEEEIQKQTQAMQELHRVELEREKARIREEYEEKIRKLEDKVEQEKRKKQMEKKLAEQEAHYAVRQQRARTEVESKDGILELIMTALQIASFILLRLFAED
Protein: Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38) (Q8R323)
Organism: Mus musculus (Mouse)
Function: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Replication factor C subunit 5
- Replication factor C subunit 4
- Replication factor C subunit 2
- Cell cycle checkpoint protein RAD17
- Replication factor C subunit 1
- Proliferating cell nuclear antigen
- Sister chromatid cohesion protein DCC1
- Chromosome transmission fidelity protein 18 homolog
- Chromosome transmission fidelity protein 8 homolog
- ATPase family AAA domain-containing protein 5
Sequence:
MSLWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACRVQQYPFTEDQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF
Protein: Possible transcriptional regulatory protein (Probably TetR-family) (O53661)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable transcriptional regulatory protein
- Uncharacterized HTH-type transcriptional regulator Rv0023
- Probable cell division protein WhiA
- Probable transcriptional regulatory protein
- Putative antitoxin VapB42
- Beta-hexosaminidase LpqI
Sequence:
MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDRLETGH
Protein: Anoctamin (A0A0B4KGH4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU280814}.
Interaction partners:
Sequence:
MTDPDFVKGNVGGVYDDRECSCPREFYQRGEINTSLFFEDCVRSIDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESSQKDQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEITETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDWCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVLQTPVDQDMDAASIQEPNAKFINIEKLLTENLTQIEMDAIIHGENPITGISGADCLDEVHKKLSD
Protein: Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Sodium- and chloride-dependent GABA transporter 4) (GAT-4) (Solute carrier family 6 member 11) (P31650)
Organism: Mus musculus (Mouse)
Function: Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA). Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P31647}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium- and chloride-dependent GABA transporter 2
- Cytosolic arginine sensor for mTORC1 subunit 2
Sequence:
MTAEQALPLGNGKAAEEARGSETLGGGGGGAAGTREARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWLMALSSMLCIPLWIFIKLWKTEGTLPEKLQKLTVPSADLKMRGKLGASPRTVTVNDCEAKVKGDGTISAITEKETHF
Protein: Nuclear factor 1 (A0A8I5ZTI5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU000690}.
Interaction partners:
Sequence:
MHSSPSDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKAEVKQKWASRLLAKLRKDIRPECREDFVLAVTGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAACAHPVLCVQPHHIGVAVKELDLYLAYFVRERDAEQSSSPRTGVGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASAGMRRTLPSTSSSGKRHKSGSMEEDVDTSPGGDYYTSPNSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPATPILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPATQQPGPVSFMAANTRHV
Protein: Glycosylinositol phosphorylceramide mannosyl transferase 1 (GIPC mannosyl-transferase 1) (EC 2.4.1.-) (Glycosyltransferase family 64 protein C4) (GT64 C4) (Protein ECTOPICALLY PARTING CELLS 1) (AtEPC1) (Q9LY62)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mannosyl transferase (ManT) required for the biosynthesis of mannose-carrying glycosylinositol phosphorylceramides (GIPCs). Maybe involved in cell-cell adhesion that maintains the integrity of organs by providing mechanical strength and facilitating the movement of metabolites throughout the plant during development. Prevents abscisic acid- (ABA-) mediated effects on development (e.g. cell size, flowering time, senescence). Probably implicated in beta-(1,4)-galactan biosynthesis thus being a cell-wall synthesis-related (CWSR) protein.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:17426055, ECO:0000269|PubMed:27895225}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
- Galacturonosyltransferase 8
- Xylogalacturonan beta-1,3-xylosyltransferase
- Probable arabinosyltransferase ARAD1
- Probable beta-1,4-xylosyltransferase IRX10L
- SNARE-interacting protein KEULE
- Probable pectin methyltransferase QUA2
- Vesicle transport protein GOT1
- Peroxidase 24
- Probable beta-1,4-xylosyltransferase IRX10
- Protein SUPPRESSOR OF K
Sequence:
MGGGEVSKEMGACSLAYRRGDQKLRKFVTARSTKFLLFCCIAFVLVTIVCRSSRPWVNSSIAVADRISGSRKGYTLLMNTWKRYDLLKKSVSHYASCSRLDSIHIVWSEPNPPSESLKEYLHNVLKKKTRDGHEVELRFDINKEDSLNNRFKEIKDLKTDAVFSIDDDIIFPCHTVDFAFNVWESAPDTMVGFVPRVHWPEKSNDKANYYTYSGWWSVWWSGTYSMVLSKAAFFHKKYLSLYTNSMPASIREFTTKNRNCEDIAMSFLIANATNAPAIWVKGKIYEIGSTGISSIGGHTEKRTHCVNRFVAEFGKMPLVYTSMKAVDSRNLWFW
Protein: Guanine nucleotide-binding protein subunit beta-like protein (Q4GZF3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nucleolar GTP-binding protein 2
- DNA replication licensing factor MCM4
- Aminopeptidase, putative
- Protein SDA1
- NLE domain-containing protein
- Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop domain-containing protein
- Ribosome biogenesis protein BOP1 homolog
- Pescadillo homolog
- Las1-like
- Eukaryotic translation initiation factor 6
Sequence:
MLFVASSSKSHLINLDTKTVERSYVTTPVERRGLVYWPTARVVMSNQSRGCASLFSPAMQQPVLRCLTPQAVTASASTSDGAFLLVGTAEGNLYVWSTLSGELLHLVRSHTRRITEIAISSDQSLIATASEDSVCKTWLLAALVARGVSAPAPRIVFNGHSLSVNACSFLDSSQSVVTASSDRSCRIFDGSTGQQQFVVTLGDVLTSVRPSPGDEMLLIGGETGSLFFVRLYSFSERQCLPTAGLIRCVNDVVTCTPFTDGHKGAIVFIHFDYTRPDYVLVGSTNGVILWWNIRTATTVEKAVDDIAGGLLSVCYVPSDATQPSSAAVPPVVLQKHPLDPLGVDFIVVSAGKKESAPISYQKEGGSRASRRKRKHQQTMEDTCVSMKRTENVVATELEEGARESTGKPTSAERFSRLREKNDELEFLKNKLKEKLRKLRAAS
Protein: Zinc finger protein 784 (Q8BI69)
Organism: Mus musculus (Mouse)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MAAARPDPPIPSSPTRESPSPEPPDLVLVPDGRPVTPPGDLIEIQVVKVTDTTSVPEPPEPGSFHCALCPAAFRLVSELLFHEHGHLASMEGLGQDGDPSRCHVCGHSCPGPASLRAHYSLHTGERPYRCSLCPRAFKALAPLLRHQHRHGVEPGTSERLLPTTTTGQPNSRVAQERSEVVMAAAAAGAVVGKPFACRFCAKPFRRSSDMRDHERVHTGERPYHCSICGKGFTQSSVLSGHARIHTGERPFRCMLCDRTFNNSSNFRKHQRTHFHGPGSGVGESRGQLRSSSVSQES
Protein: Homeobox protein Hox-B1 (Homeobox protein Hox-2I) (P14653)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.
Subcellular location: Nucleus.
Interaction partners:
- Pre-B-cell leukemia transcription factor 1
- Homeobox protein PKNOX1
- Homeobox protein Hox-D1
- Homeobox protein Hox-A1
- Lysine-specific demethylase 6A
- E3 SUMO-protein ligase EGR2
- Homeobox protein PKNOX2
- Homeobox protein Hox-B2
- Lysine-specific demethylase 6B
- Homeobox protein Meis1
Sequence:
MDYNRMNSFLEYPLCNRGPSAYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREEGRVPPAPPGCPKEAAGDASDQSTCTSPEASPSSVTS
Protein: Small ribosomal subunit protein eS12 (40S ribosomal protein S12) (P63324)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:P25398}.
Interaction partners:
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein eS25
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS8
- Small ribosomal subunit protein eS8
- Ubiquitin-ribosomal protein eL40 fusion protein
- Small ribosomal subunit protein uS7
Sequence:
MAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALLAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK
Protein: Ribulose bisphosphate carboxylase large chain (RuBisCO large subunit) (EC 4.1.1.39) (Q8DIS5)
Organism: Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)
Function: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.
Subcellular location: Carboxysome {ECO:0000255|HAMAP-Rule:MF_01338, ECO:0000269|PubMed:25041569}. Cytoplasm {ECO:0000269|PubMed:25041569}.
Interaction partners:
- Ribulose bisphosphate carboxylase small subunit
- Carboxysome assembly protein CcmM
- RuBisCO accumulation factor 1
- RuBisCO chaperone RbcX
- Phosphoribulokinase
- Phosphoglycerate kinase
- Tll1470 protein
- Elongation factor Tu
- Carboxysome shell protein CcmK2
- Carbon dioxide concentrating mechanism protein
Sequence:
MAYTQSKSQKVGYQAGVKDYRLTYYTPDYTPKDTDILAAFRVTPQPGVPFEEAAAAVAAESSTGTWTTVWTDLLTDLDRYKGCCYDIEPLPGEDNQFIAYIAYPLDLFEEGSVTNMLTSIVGNVFGFKALKALRLEDLRIPVAYLKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFQRWRDRFLFVADAIHKAQAETGEIKGHYLNVTAPTCEEMLKRAEFAKELEMPIIMHDFLTAGFTANTTLSKWCRDNGMLLHIHRAMHAVMDRQKNHGIHFRVLAKCLRMSGGDHIHTGTVVGKLEGDKAVTLGFVDLLRENYIEQDRSRGIYFTQDWASMPGVMAVASGGIHVWHMPALVDIFGDDAVLQFGGGTLGHPWGNAPGATANRVALEACIQARNEGRDLMREGGDIIREAARWSPELAAACELWKEIKFEFEAQDTI
Protein: Cdc42 effector protein 5 (Binder of Rho GTPases 3) (Q9Z0X0)
Organism: Mus musculus (Mouse)
Function: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:11035016}; Peripheral membrane protein {ECO:0000269|PubMed:11035016}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11035016}.
Interaction partners:
- Cdc42 effector protein 2
- Cell division control protein 42 homolog
- Cdc42 effector protein 3
- Leukocyte receptor cluster member 8 homolog
- Septin-7
Sequence:
MPVMKQLGPAQPKKRLDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPGAPPVVAPHSVAPPAAPQPPVAVPSPADPLLSFHLDLGPSMLDAVLGVMDAERSETTATKPDGDAHPRVQHPKTRCCSNADLQLDDVIGL
Protein: MIP03712p (Sclp, isoform B) (C0PV74)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAHLVVRVIERCENANESAHLDLSSCELMQIPDAVYHLMRNTELITCNLSGNVLKSVSPKFSQKFSTITDLNLSHNKLSRLPEEFASLSALTKLNISNNSFIVLPQVVFKLQSLASLDAQNNAILEIDTDEAITSDNLALVDLRNNPLSRNCRRKLQSFKTPFHLEISKDVEDDW
Protein: Minor head protein GP7 (Accessory head protein gp7) (Q38442)
Organism: Bacillus phage SPP1 (Bacteriophage SPP1)
Function: Binds the viral DNA inside the capsid and the portal protein. May control the DNA exit from the virion.
Subcellular location: Virion {ECO:0000269|PubMed:10656821, ECO:0000269|PubMed:9180375}. Note=Probably located next to the portal vertex. Present in one to two copies per virion. {ECO:0000305|PubMed:10656821}.
Interaction partners:
Sequence:
MPEPQNQEELDKYLDNIITQAEKRLDKVFASRLKEIKAMINKLFEKYSKNGELTYADVVKYNRLEKEMDVIKQNISADYKTVLKMLNELLETQYVDNYLRSAYIYEMYTGRNLGFSVPSADVVQRAVENPIPLLTLPKVLERQRVELINNIAMAIAQGLMAGEGYSQVAQRVHKRMQLSLAKARLTARTEGHRVQVAGRMASAEQAAKKVNMQKMWSAALDTRTRAGHRKLDGKIINMDENFKSIYGGVGKAPGHMHMAKDDCNCRCALIYVIDGEIPSVRRARLSDGSTRVIKYIPYTEWEKQKKAS
Protein: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (cDNA FLJ77531, highly similar to Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), mRNA) (A7E2E1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
Protein: Myosin-7B (Antigen MLAA-21) (Myosin cardiac muscle beta chain) (Myosin heavy chain 7B, cardiac muscle beta isoform) (Slow A MYH14) (A7E2Y1)
Organism: Homo sapiens (Human)
Function: Involved in muscle contraction.
Subcellular location: Membrane {ECO:0000269|PubMed:15755502}; Peripheral membrane protein {ECO:0000269|PubMed:15755502}.
Interaction partners:
- Myosin light chain 1/3, skeletal muscle isoform
- Transcriptional regulator protein Pur-beta
- Transcription factor SOX-6
- Myosin light chain 3
- Mediator of RNA polymerase II transcription subunit 13
- Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
- Tropomyosin alpha-3 chain
- GPI-anchor transamidase component PIGU
- Myosin light chain kinase 3
- Myosin regulatory light polypeptide 9
Sequence:
MSGNKRGSRASCPHRGAECLLPWAALNLQGFQLLLLHPSATAMMDVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTRDALGPKHKE
Protein: Serine hydrolase-like protein (SHL) (EC 3.1.-.-) (Q9EPB5)
Organism: Mus musculus (Mouse)
Function: Probable serine hydrolase. May be related to cell muscle hypertrophy.
Subcellular location: Cytoplasm, perinuclear region. Peroxisome. Note=Concentrated in perinuclear vesicles. May be located in peroxisomes.
Interaction partners:
Sequence:
MGLHSELKLAVPWGHIALKVWGSQKNPPVLCLHGWLDNANSFDRLIPLLPQDFCYMAMDFGGHGLSSHYNPGLPYYQQNFVSEVRRVATAFKWNQFTLLGHSFGGCVGGTFACMFPEMVDKLILLDSTPFFLDSNEMENILTYRRRNIEHTLQVEASQKKSLRAVSPEEMLQGFLNNNSHLDKDCGELILQRGTTKVDAGLVLNRDRRISWPENSFDFVSKEMFVHSAKSLQASVLMIKALQGYYDVRRANDADKAPMHFMVDTLRSTLKERFQFVEVPGNHYIHMNKPQVVAGVVGPFLQGLQRMTSARL
Protein: Feruloyl esterase (F8SUI7)
Organism: uncultured bacterium
Interaction partners:
Sequence:
FVIKYVWQAFKKLCLLLCISEWLLDNSGEERGDCGNRRTGTPCGWSLGNGDGGFFQWCWLCARVRWQSWSTSSKAAVLANAVPPVIMWSIDTRDWVNAVMSQVRDGDIVLMHELYEQSGIAAEIIPELTEAGYQLVTVSEMAALRGGMSPGGSYFHFRYPEWVSW
Protein: U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 tri-snRNP-associated protein 3) (Q9W1I6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Tetraspanin 68C, isoform A
- GH25653p
- U6 snRNA-associated Sm-like protein LSm7
- Ubiquitin carboxyl-terminal hydrolase 39
- Uncharacterized protein, isoform A
- Probable small nuclear ribonucleoprotein G
- U5 small nuclear ribonucleoprotein 40 kDa protein
- Precursor RNA processing 3, isoform A
- RE11167p
Sequence:
MGRSRSPASPAHRRREKERSERKKRRERRSREREAIGVAPAGGSGSGGAGRRDRERDRDRSRSRDRERERERDRARSRRSRSRSRVAGGGGGGGGGGSSGGNSSSGPSTSRRTTRNNAAATAADRPKINEADLEGKSPEEVEMLKTMGFCTFDTTKNRKVEGNDVGEVHVILKRKYRQYMNRKGGFNRPLDFVA