wanglab/gogpt-training-data huggingface dataset:
Protein: Cullin homolog 1 (Lin-19 homolog protein) (Q24311)
Organism: Drosophila melanogaster (Fruit fly)
Function: Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larval ddaC dendrites and mushroom body axons. The SCF-slmb complex also regulates asymmetrical division of neuroblasts and inhibits ectopic neuroblast formation partly through SAK and Akt1. Also part of an SCF complex required for caspase activation during sperm differentiation. Necessary for auditory transduction: plays a role in Johnston's organ organization by acting in the regulation of zip and ck function in scolopidial apical attachment. May function by acting in a Ubr3-mediated pathway that negatively regulates the ubiquitination of zip, consequently affecting its interaction with ck.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20392747}. Note=In the spermatid, colocalizes with ntc at the actin-based individualization complex and the cystic bulge.
Interaction partners:
- SKP1 component POZ domain-containing protein
- SKP1-related D
- Ubiquitin-like protein NEDD8
- Supernumerary limbs, isoform B
- GEO01111p1
- RING-box protein 1A
- GEO10396p1
- CG11942
- LP10147p
- S-phase kinase-associated protein 2
Sequence:
MNRSGNSQTTQKLVNLDDIWSELVEGIMQVFEHEKSLTRSQYMRFYTHVYDYCTSVSAAPSGRSSGKTGGAQLVGKKLYDRLEQFLKSYLSELLTKFKAISGEEVLLSRYTKQWKSYQFSSTVLDGICNYLNRNWVKRECEEGQKGIYKIYRLALVAWKGHLFQVLNEPVTKAVLKSIEEERQGKLINRSLVRDVIECYVELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAFYEKESDAFLSTNTVTEYLKHVENRLEEETQRVRGFNSKNGLSYLHETTADVLKSTCEEVLIEKHLKIFHTEFQNLLNADRNDDLKRMYSLVALSSKNLTDLKSILENHILHQGTEAIAKCCTTDAANDPKTYVQTILDVHKKYNALVLTAFNNDNGFVAALDKACGKFINSNVVTIANSASKSPELLAKYCDLLLKKSSKNPEDKELEDNLNQVMVVFKYIEDKDVFQKYYSKMLAKRLVNHTSASDDAEAMMISKLKQTCGYEYTVKLQRMFQDIGVSKDLNSYFKQYLAEKNLTMEIDFGIEVLSSGSWPFQLSNNFLLPSELERSVRQFNEFYAARHSGRKLNWLYQMCKGELIMNVNRNNSSTYTLQASTFQMSVLLQFNDQLSFTVQQLQDNTQTQQENLIQVLQILLKAKVLTSSDNENSLTPESTVELFLDYKNKKRRININQPLKTELKVEQETVHKHIEEDRKLLIQAAIVRIMKMRKRLNHTNLISEVLNQLSTRFKPKVPVIKKCIDILIEKEYLERMEGHKDTYSYLA
Protein: Putative L-ascorbate peroxidase 6 (AtAPx08) (EC 1.11.1.11) (Q8GY91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a key role in hydrogen peroxide removal.
Interaction partners:
- L-galactono-1,4-lactone dehydrogenase, mitochondrial
- Monodehydroascorbate reductase 3
- Glutathione S-transferase DHAR3, chloroplastic
- Glutathione S-transferase DHAR1, mitochondrial
- Glutathione S-transferase DHAR2
- Monodehydroascorbate reductase 2
- Monodehydroascorbate reductase 1, peroxisomal
- Monodehydroascorbate reductase, chloroplastic/mitochondrial
- Monodehydroascorbate reductase 4, peroxisomal
Sequence:
MTTTTASLVKTFLFRCDSFSSFKFKCKFESPAKTRLLSPATEKHVVRSSRAWRIRCLSDDPGSSHVFVASRRKMVVLLSTVQLLSHMLPQNGNAAEIYPVMQNEIRKVVTKGKAAGVLRLVFHDAGTFELDDHSGGINGSIAYELERPENIGLKKSLKVLAKAKVKVDEIQPVSWADMISVAGSEAVSICGGPTIPVVLGRLDSAQPDPEGKLPPETLSASGLKECFKRKGFSTQELVALSGAHTIGSKGFGDPTVFDNAYYKILLEKPWTSTSKMTSMVGLPSDHALVQDDECLRWVKRYAEDQDKFFEDFTNAYIKLVNSGAKWNML
Protein: DNA fragmentation factor subunit beta (EC 3.-.-.-) (Caspase-activated deoxyribonuclease) (CAD) (Caspase-activated DNase) (DNA fragmentation factor 40 kDa subunit) (DFF-40) (O54788)
Organism: Mus musculus (Mouse)
Function: Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- DNA fragmentation factor subunit alpha
- Caspase-3
- Histone H1.0
- Endonuclease G, mitochondrial
Sequence:
MCAVLRQPKCVKLRALHSACKFGVAARSCQELLRKGCVRFQLPMPGSRLCLYEDGTEVTDDCFPGLPNDAELLLLTAGETWHGYVSDITRFLSVFNEPHAGVIQAARQLLSDEQAPLRQKLLADLLHHVSQNITAETREQDPSWFEGLESRFRNKSGYLRYSCESRIRGYLREVSAYTSMVDEAAQEEYLRVLGSMCQKLKSVQYNGSYFDRGAEASSRLCTPEGWFSCQGPFDLESCLSKHSINPYGNRESRILFSTWNLDHIIEKKRTVVPTLAEAIQDGREVNWEYFYSLLFTAENLKLVHIACHKKTTHKLECDRSRIYRPQTGSRRKQPARKKRPARKR
Protein: Transport protein particle subunit bet3 (TRAPP subunit bet3) (Q9P6P5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi apparatus, cis-Golgi network {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Interaction partners:
- Transport protein particle 20 kDa subunit
- Uncharacterized protein C13G6.05c
- Transport protein particle subunit trs120
- Transport protein particle subunit trs31
- Uncharacterized protein CC285.14
- Transport protein particle subunit trs23
- Transport protein particle subunit bet5
- Uncharacterized protein C15A10.12c
- GTP-binding protein ypt1
- Transport protein particle subunit trs85-2
Sequence:
MSKSKIGEDVYKKVDKVNAELFVLTYGSIVAQLCKDMNYEKVNEELDKMGYNIGIRLIEDFLAKTEWPRCADFRETGETVAKVGFKVFLNFSPIISSVSDDGNTFVLTLDDNPLAEFVELPADARQKLWYSNILCGVIRGALEMLQMDVDAVFLRDILRGDEHTEIRVHLKRILKEEIPPGDE
Protein: Prolyl endopeptidase (EC 3.4.21.-) (F4HSS5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Acylamino-acid-releasing enzyme
- Methylesterase 3
- Fas-binding factor-like protein
- Alpha/beta-Hydrolases superfamily protein
- Probable carboxylesterase 12
- Serine carboxypeptidase-like 50
- Methylesterase 2
- Probable E3 ubiquitin-protein ligase WAVH2
- F-box protein At1g47056
Sequence:
MGSLPAFEERLQYPTARRDESVVEDYHGVKVSDPYRWLEDPDAEEVKEFVEKQVQLSDSVLKSCETKEKLHDKFTKFIDYPRFDTPFKRGNSYFYFHNSGLQAQSVLHVQDDLESEAEILLDPNTLSDDGTVSLNTLSISEDAKYLAYGLSSSGSDWVTIKVMKIEDKKVEPDSLSWVKFSGITWTHDGKGFFYSRYPAPREGEKIDAGTETNSNLYHELYYHFLGTDQSEDVLCWRDQDNPKHMFGSKVTDDGKYLIMSIEEGCDPVNKVYHCDLSLLPKGLEGFRGSNTLLPFVKLIDTFDAQYIAIANDETLFTFLTNKDAPKYKVVRVDLKEPSSWTDVIAEHEKDVLSTASAVNGDQLVVSYMSDVKHILQIRDLKSGSLLHGLPVDIGSVCGVFARRKDTTFFFRFTSFLTPGVIYICDLSHEAPEVTVFREIGVPGFDRTAFQVTQVFYPSKDGTDIPMFIVARKDIKLDGSHPCLLYAYGGFSISMTPFFSATRIVLGRHLGTVFCFANIRGGGEYGEEWHKSGALANKQNCFDDFISGAEYLVSAGYTQPRKLCIEGGSNGGILVGACINQRPDLFGCALAHVGVMDMLRFHKFTIGHAWTSEFGCSDKEEEFHWLIKYSPLHNVKRPWEQKTDLFFQYPSTMLLTADHDDRVVPLHSYKLLATMQYELGLSLENSPQTNPIIARIEVKAGHGAGRPTQKMIDEAADRYSFMAKMVDASWID
Protein: Raw, isoform A (Raw, isoform C) (Raw, isoform E) (Q9VLI4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Transcription factor Jra
- Transcription factor kayak, isoforms A/B/F
Sequence:
MKTESSSYLGKMRLQHRYASNSTTNSSNNTTISTASNASNNNNIKRAKKLSGQNIIKLRSAKQSAAKSTASSSTTMPPATPQPLSRHHPIMMDKELESAKETAVLSSNNDQKLKDEDIEETTSTTTTSVELRSSASSHYRAYTTIRSNSTSAILHEAVLPPPLTPAGMLYARPRTLNVHNVCQTPAQITQMFFGEVLNAWRAKARCNVVPDERTQELFHELSFHPSQKQISEMLQTAKKVARKGGSGQANGLTFGQFCVLAADLKRFRASTISNQPSYCDYQSLSAGLLLPELDDPASSSNQNLQSPAATNSSPAHSSKKPDNHGTELRSTKSFSSVDDTKKKKNATNEPVEVFLGGSCNPTTWRADVAIPALKELGISFYNPQVSDWTPDLIELEHRAKEKARVLFFVMDSETRASAGAIEAAHIAGQNCKQLVLVLHPYKPNQKILNEPISQQEYLDLNRNQLILKELVSRRGLPVLDNIPLGLQRTKDILGGIRDPPSKISSILDTVRGAFDRVNPLNDLLTVEQCKRALLFLGYAQSLVNLDNLNKIIINQRESLKLLQTHSPRAVADDADADGGNCSQPILPSQELIDFDLFCVISAYLSVLQQEIHESGCISPIKGTNVPPPQVYFTNAPDVDIYYSASKNISRTSSNASVPSNSSSGIGHDLERQSLFEQLSRSRDSGTSSPQPTGSSSLGKSPRPQILLNVESIETTEIITTKTIETKPNPVTASTVVHAEEEESDSNDSVLSSNSSIASAGDILCCGGGLDLRDVYLGGSCVLRTKWRQELAVPYLQSKGVSFHTPALHESIQQMILNQEQNQDQSQQPTVPPQEQQQQQRSFVRTRRKCRGNQLQLEEQEELTVAEESLSWSLPPVAVRQSLFNPSLLDSSRVLLFVITNETRSLAPMTLAAHCIGLMYNVVLAVQMLPEDCVLGDEKLTVAAIKDYNRGRSYLIDLAKRQGVPVFSDIRAALECTVAKVKAYNNRDRC
Protein: AcrH (Q6TLM1)
Organism: Aeromonas hydrophila
Interaction partners:
Sequence:
MEHDMTQVNEPAIEAFLQDGGTLAMLNDVSTDTLEQLYTLGFNQYHAGKHDEAHKIFQALCVLDHYEARFFLGLGACRQALGQFRLAIDSYSYGAMMDLQEPRFPFRAAECLLQLGELEGAESGFHSAQLLAAAKPELAELAARAGIMLEVVKTKKDMEHAFDKQ
Protein: GH05665p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Q9VHE3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Grasp65
- Ras-related protein Rab-2
- Golgin-84
- LD35087p
- 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
Sequence:
MEANESAMPGTDKSQACRTSGDGMEQPENSGAAKTESEIPASADVDNKVKRPQLSRKDSSVVQEAVMGRKTSTSSGHSSNLPLPGLHTLYRRPENVTRSLAPVVPKGELVQMRPRLVTSADSLPEHKKTKAPKFVPYEPYPGAVNPMISEPTNKHKIHRDKNNLDIAVLVDQVSTLRTQELETETTDIKETDTASSHEVNSLKEELAKMRDERNYFQAQYKFQTQVNSELKSLLVASVGEDLQTRVNLLTEDKLQLARALLDTANNLTTHTEQIEFLAGQCEVWRSKFLASSVMVEELARWKADLTQKNQLLNESTKQLLHATHQIREIQLDMLKQLKFLAKIRFLNLPATDVISLSAENLNILQRMVLHTGVGIPEETLKLSSASTSPLCEAEKYAVRALEFISQPLMATDEAIRALFDQAQRPHYVQSPASEVTPACDNQQLDKMQ
Protein: Leucine-rich repeat-containing protein ODA7 (Dynein assembly factor 1, axonemal homolog) (Leucine-rich repeat-containing protein 50 homolog) (Outer row dynein-assembly protein 7) (Q09JZ4)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Cilium-specific protein required for cilia structures. Axonemal dynein-associated protein that participates in a structural link between inner and outer row dyneins.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:17194703}.
Interaction partners:
Sequence:
MCACMTKEALLEVCKQNGLYRTASLNDKLYCNFKGFSQIACLEDYVNLKALFLEGNVLETLEGLPPLADLKCLYVQQNCIWKISGLEAVPGLDTLNISNNQLTKLEGLACCPALRTLIATHNHLVTLDSVAHLAECKALQTLDLQNNELEDPGIVDILKQIPDLRCLYLKGNPVVSNIKNYRKVLVTSIPSLTYLDDRPVFDNERKIAQAWLEGGLEGERAMRNQLKEEEEERSRKNHEFMMQMRAAGWRERRKRMGLPDGDTDPALDDMSDGEYEFDEEPEELVEARQRLAAYTARPGEEEPAELASARQGLARDGKPIQEGAWGSGAAAESDSAIYLQSVKAAQAELDVVRQQQPRQLPTAQVLIEELDEPCGGKAPAADEGSTPPALSPMTSPSGSEGQGGEGVAAAKKGAASGAAEGISAAVDINDLD
Protein: Uncharacterized protein (Q9VTV7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDKNLDEVKDTVQKKFNEIRAALHMREKLLLRQLEVIANTRQQQQLLKKSPTEMENSNSVGKKDQSGVRFIPGESEDAEEKLLTAIRSYGHFLLDNSDMQLALQDYRTTGLRNEDYIEPLDDHETMYKCLQDGQVSYLDLDEDGAPPEAIVVDFSRNRSLVEDNAKRSIINITLQEAKDLIKKAKIKRDTYVPPLNLEELDDELESSIAEAVSSLGRETSAKSKSSVQEPPKCKGRKQRFKPKITINNCNGTINLRNIASLTINCASEEAVSAEMPLAKSADSSTTEPSNSTPTTTASSSNYSSNASSRSQSKKQKANKKLDKIEREPSSDSTPTPGQAQRYEETEIHDVTCDFYNRLLNEIKKSMVEKPRRTYNQLAEPVQTSAADSSCDANCNPKQSAAKQEPVSTTTSLTHSESGPQLQPGKRLILKNFENLKIILEANSGDEDSFHPVQIEQWLAEIISETDLEPMQNTDILEHSRIHSSESP
Protein: Glutamine synthetase (EC 6.3.1.2) (A8WCU6)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSLLTDLVNLNLSDCTDKIIAEYIWIGGSGMDLRSKARTLSGPVSDPSKLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRCNAAKIFSHPDVAAEEPWYGIEQEYTLLQKDVKWPIGWPLGGYPGPQGPYYCGVGVDKAYGRDIVDSHYKACLYAGINISGINGEVMPGQWEFQVGPAVGISAGDELWVARYILERITEIAGVVLSFDPKPIQGDWNGAGAHTNYSTKSMRSDGGYEVIKKAIAKLGLRHKEHIAAYGEGNERRLTGRHETADINTFLWGVANRGASIRVGRDTEKAGKGYFEDRRPASNMDPYVVTSMIAETTIPWKP
Protein: PWWP domain-containing protein 1 (F4K4D6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Together with PDP2, PDP3 and PDP6, interacts with MSI4/FVE and MSI5 to suppress FLC, MAF4 and MAF5 expression by regulating the function of the PRC2 complex and modulating H3K27me3 level, thereby promoting flowering.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- WD-40 repeat-containing protein MSI4
- VIN3-like protein 2
- Adenosylhomocysteinase 1
- Adenosylhomocysteinase 2
- PWWP domain-containing protein 2
- WD-40 repeat-containing protein MSI5
- PWWP domain-containing protein 3
- Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1
- ARM repeat superfamily protein
- PWWP domain-containing protein 4
Sequence:
MYKTKLIPVMNEDAVIVQQTDSIQDPKVTPDDTVVDSSGDVHEAIDDDVEASSPMELDSAVTNDARVLESERSEKDGVVGSEEEDEIKSEDVLIDKDDESSEVKEEEEEEDGSDDQSSELGSEADEKELDLGLKEEKKGVSDYKSLLSEFDDYVASEKMGSGVSRALSYGFEVGDLVWGKVKSHPWWPGHIFNEAFASPSVRRMRRIDHVLVAFFGDSSYGWFDPAELIPFEPNLEEKSQQTVSKHFVRAVEEAKDEASRRSALGLTCKCRNPYNFRPSNVEDYFAVDVPDYELQAVYSVDQIKNSRDKFLPAETISFVKQLALAPQECDPDSLKFMKKKAVVFAFRKSVFEEFDETYAQAFGTKSPRSSVSTLEPHNRAPPRAPLSGPLVIAETLGDLKSSKKPTKVKVSKKKDKYLLKRRDEAGDKSVQFGEIEASSEASHIQGIDGSLDGDFGLQRRAPTLQTPMKDEKSGIVSMDFASSNTAIPGKEFSASKPSLDEEKGLAEKSKERMEERAAVLPEHGKSEAMASLKPKEEAGTDLGSAGSSLQPLLESHTSASEGKSSTGSVIKKVKVAKRSSSEMSSENPPSEPKKKKKKKKEPDSDHPVKRKNLYSGEAGAKKLSQLGSAHLQTYMEADVPQLLSHLQDLSLDPFHGLSVASFGTARKFFLRFRSLNYQKSLSVSSSDATVENARDTKPSKPVKTVKRTEDPSKAGKKRLSSDRQDEIPSAKKLKKTNQLKSMASEKKIIREAKDSIKPIREPSRVVQAKPARGQTGKKTAPSVKVVEPTMLVMKFPPGTSLPSAALLKARFGRFGLLDQSAIRVFWKSSTCRVVFLYKADAQTAFRYATGNNTLFGNVNVKYFLRDVDAPKAEPREPENTKEDDEPQSQWLDQAPPLHQPTLPPPNVNLKSCLKKPVDDPSSSSNNGNGNRAAVRVKFMLGGEENSSKANTEPPQVTMTLNRNSGPSSSSSSVPMEFVSKKFQNVVHHQQLPPSTLPPILPLPPQYTKPQQLPIKPVDHVEPPMPPSRNFRGPIPAVSAGDISHQMLNLLSKCNEVVANVTGLLGYVPYHPL
Protein: Zona pellucida-binding protein 1 (Inner acrosomal membrane IAM38) (Sp38) (Q62522)
Organism: Mus musculus (Mouse)
Function: Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9BS86}. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000269|PubMed:17664285, ECO:0000269|PubMed:19204925}; Peripheral membrane protein {ECO:0000305|PubMed:19204925}. Secreted {ECO:0000305}. Note=First localized in acrosome granule, later migrates to the inner and outer acrosomal membrane (PubMed:19204925). Released after the acrosomal reaction (PubMed:17664285). {ECO:0000269|PubMed:17664285, ECO:0000269|PubMed:19204925}.
Interaction partners:
- Zona pellucida sperm-binding protein 3 receptor
- Zona pellucida-binding protein 2
- T-complex protein 1 subunit gamma
- Heat shock 70 kDa protein 1-like
- T-complex protein 1 subunit theta
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit zeta
- Heat shock 70 kDa protein 1B
Sequence:
MEALAPGRAPRGRRRAGASGSVLSPLSLAAVLLCALLRAPPAVGHLARLPRSIHLTQDSLKIVGSTHFPVSVYVMLHQKSPHVLCVTQRLRNTELVDPSFQWHGPKGKLVSENTTAQVTSTGSLIFQSFEETMSGVYTCFLEYKPTVEESIKNLQLKYIVYAYREPRFYYQFTARYHAAPCNSIYNISFEKKLLQILSKLVLDLSCEISLIKSECHRVKMQRAGLQNELFFTFSVASIDTEKGSKPCTDHSCEASKRLSKAKNLIERFFIQQVEVLGKRAEPLPEIYYIEGTLQMVWVNRCFPGYGINVLKHPKCPECCVVCSPGSFNPRDGTHCLQCNNSLVYGAKTCM
Protein: RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A) (Q642J5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- RNA-binding protein 24
- Muscleblind-like-splicing regulator 1.
- CUGBP Elav-like family member 2
- Serine/arginine repetitive matrix protein 4
- NOVA alternative-splicing regulator 1
Sequence:
MEEKGSKMVEQGNQDAPAPPETMAQPFPSAQFAPPQNGIPAEYTPSHPHPTPDYSGQTPVAEHTLNLYTPAQTHSEPSGPDNSIQAVSGTATQTDDSAQTDSQQQTQSSEITEIKTQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFESSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYANGWKLNPVVGAVYSPEFYAVPGFPYPAATAAAAAYRGAHLRGRGRTVYNTFRAAAPPPHIPAYGGVVYQDGFYGADIYGGYTAYRYTQPATATAAAYSDSYGRVYAADPYNHALAPAATYSVGAMNAFAPLTDAKTRSHADDVGLVLSSLQASIYRGGYSRFAPY
Protein: U3 small nucleolar RNA-associated protein 6 (U3 snoRNA-associated protein 6) (O60188)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the SSU processome, a pre-ribosomal particle required for the maturation of the 18S rRNA from the 35S pre-rRNA precursor.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Uncharacterized protein C57A7.06
- U3 small nucleolar RNA-associated protein 22
- U3 small nucleolar RNA-associated protein 10
- U3 small nucleolar RNA-associated protein 21 homolog
- Probable U3 small nucleolar RNA-associated protein 18
- Uncharacterized protein C18B11.06
- U3 small nucleolar RNA-associated protein 17
- Probable U3 small nucleolar RNA-associated protein 13
- Periodic tryptophan protein 2 homolog
- U3 small nucleolar RNA-associated protein 4
Sequence:
MAEKVQYYMEQSVPELEDLLEKNIFNRDEINNIIKTRRVFEEKLARRQVKLNDFLSYIQYEINLETLRAKRHKRLNITGKITISDYAGPRKVLFLFLRATNKFFGDVTLWLDYIHYAQKIKAVNIVGKICVAALQKHPNNAELWVVACDHEFSINANVSAARALMNRALRLNQENPVIWAAYFRLELSYMTKLFARSQILTGNISSKTENITNGVSEDTIGSLSSDTIQLPMVSMEEFLGSSSSEVRKNDSDLNISDDIGNISSKEQQTQKFANVLLQIILNSRKNLSLQNYVGFFVSVLDALFECFDVPVVQYMYQENIIGICNEHFEHFKNESGEIYGVLLHRWCFLEIFIKLRGAYPSNDSGISGKGIFGLKKNDPRITSMVLTDPGFVDDLQAIVEKYQSISSDFQIPFKTKKIFYSFFVKTLHAISSSSAAESSIALALHMLVINAFQSMEKLKILTFDDSLQEIYKEAQIQSGTFMSNATLS
Protein: Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) (F4HQ84)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. Involved in pollen tube growth by modulating Golgi morphology and vesicle trafficking homeostasis leading to the deposition of cell wall components and proteins at the pollen tube tip. Required for sporophytic development.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:27448097}; Peripheral membrane protein {ECO:0000250|UniProtKB:P40094}; Cytoplasmic side {ECO:0000250|UniProtKB:P40094}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 7
- Conserved oligomeric Golgi complex subunit 2
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 5
- Vacuolar protein sorting-associated protein 54, chloroplastic
- Proline-rich family protein
- Vacuolar protein sorting-associated protein 52 A
Sequence:
MATKAASSSSLPKSGAISKGYNFASTWEQSAPLTEQQQAAIVSLSHAVAERPFPANLVHEHVHRPENGLSVSVEDTHLGDSGAIEAVLVNTNQFYKWFTDLESAMKSETEEKYRHYVSTLTERIQTCDNILHQVDETLDLFNELQLQHQGVTTKTKTLHDACDRLLMEKQKLMEFAEALRSKLNYFDELENVSSNFYSPNMNVSNSNFLPLLKRLDECISYIEDNPQYAESSVYLLKFRQLQSRALGMIRTYILAVLKTAASQVQAAFRGTGGNKTSVSEGVEASVIYVRFKAAANELKPVLEEIESRSARKEYVQILAECHRLYCEQRLSLVKGIVHQRVSDFAKKEALPSLTRSGCAYLMQVCHMEHQLFTHFFPASSEEVSSLAPLVDPLSTYLYDILRPKLIHEANIDLLCELVHILKVEVLGDQSARQSEPLAGLRPTLQRILADVNERLTFRARTYIRDEIANYTPSDEDLDYPAKLEGSPNTTSETDLRDDENADVFKTWYPPLEKTLSCLSKLYRCLEQAVFTGLAQEAVEVCSLSIQKASKLIIKRSTTMDGQLFLIKHLLILREQIAPFDIEFSVTHKELDFSHLLEHLRRILRGQASLFDWSRSTSLARTLSPRVLESQIDAKKELEKCLKTTCEEFIMSVTKLVVDPMLSFVTKVTAIKVALSSGTQNHKVDSVMAKPLKEQAFATPDKVVELVQKVYAAIQQELLPILAKMKLYLQNPSTRTILFKPIKTNIVEAHTQVESLLKAEYSAEEQANINMISIQDLQTQLDNFL
Protein: Heterogeneous nuclear ribonucleoprotein R (F7B5B5)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPMRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK
Protein: Sulfhydryl oxidase (EC 1.8.3.2) (Q8SX43)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSAEANPEMDKEHHESPFAANRKAGASGAGKQDSNCRTCNDFKSWSKQQRLISNVQSAKVKHMAAAEKLTVNAAEDPLPRDDCPLDKVRLGISTWGLLHTMAAFYSDNPTDTEKRDMKTFFEVLSRLYPCEFCAKDFRTDLDVNPINVNSQKELALWLCKFHNRVNDKLGKPLFDCTKVNERWRDGWLDGSCD
Protein: Candida glabrata strain CBS138 chromosome A complete sequence (Q6FY32)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome E complete sequence
Sequence:
MATRTMLFLLLLVQYVFASNSSEVPLEQYFKSDLRFPNIPVGLTRDGMYYVNATLGTPGQWQQLGLGLAQPYVWVVSGDADSQCNRLDSGCLSGPLYYPQESRTSSTGGDKYSINFIDGISLNGTRYMDVMRLMNVSSSLNVSGVDSGVSFRNHTLTVQNLSFFNADYSSGYLYGSLGLGGTLNSDTELEGDFINHSFFFLDALKEARLINSSSYSLWLGSQKRNGFADTSDANEAGYLIFGAVDPNLVEGEFRKFDMIPYIHPQTGKVAYGYPVVPMGPIYITSSSGRSLNVTTDGFSAPVLLDPSFALSYLPTKAIIQIAIQIAAVYVESLDLWLVSCDVASSGATVDFSFGDLTIKVPLSDLLASTHDQSTNTTLHFNTGQEACVLQLYPNTFTGYNVLGQAFMKNAYLAVDLEGKGVAMGQAANFKSGERKEIITRQASIVTFTDSLNKTSVATFSTVPSSMTSGYIPYATYESDSAYDSMQLYPSKVGSRITSIPGQIAGTVYPGGVIAGDGRSFYDTSRTTTKLQTSTQFDSFSLSGTLGWNDSLASTSSTSRRNTAQHTSPAWLVSLLGTACVLLGSMVI
Protein: Phosducin-like protein 2 (Q71A38)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- 1-Cys peroxiredoxin
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit zeta
- T-complex protein 1 subunit theta
Sequence:
MGLGKTEWEDIQIKYGNMEAPPKQLTEDELFDLIKEAAEMATEAEKNEKLENASLKDLKDMEDDEDEDVLEQLRKKRIQQMKVEAELNKFGELKEISEPSYKSEVTECKGVMVVVHLFKNGIPQCQLVNQHLTILAKKFKATKFVKIRSEEAIHNYPDKNLPTILVYFNGDIVGQIITLRATGGDATTVNDIEWQLKQAHAIKSDLQEDPRITLARKKSQKSRYSKADSDESDNSDSDD
Protein: NADH-quinone oxidoreductase subunit J (EC 7.1.1.-) (NADH dehydrogenase I subunit J) (NDH-1 subunit J) (NUO10) (P0AFE0)
Organism: Escherichia coli (strain K12)
Function: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- NADH-quinone oxidoreductase subunit C/D
- NADH-quinone oxidoreductase subunit L
- NADH-quinone oxidoreductase subunit M
- NADH-quinone oxidoreductase subunit G
- NADH-quinone oxidoreductase subunit B
- NADH-quinone oxidoreductase subunit N
- NADH-quinone oxidoreductase subunit K
- NADH-quinone oxidoreductase subunit I
- NADH-quinone oxidoreductase subunit A
- NADH-quinone oxidoreductase subunit H
Sequence:
MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFFSLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAIMLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGREERAGEVLSNRKDDSAKRKTEEHA
Protein: Homoserine O-acetyltransferase (HAT) (EC 2.3.1.31) (Homoserine transacetylase) (HTA) (Q97PM9)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00295}.
Interaction partners:
Sequence:
MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMDSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLCWSSSAALFFSNWVDHAVYQETPFDWRKIEDDASAYGYL
Protein: Histone H4 (P62805)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P62806}. Chromosome. Note=Localized to the nucleus when acetylated in step 11 spermatids. {ECO:0000250|UniProtKB:P62806}.
Interaction partners:
- Histone-binding protein RBBP4
- Histone H2A type 1-B/E
- Histone H2A type 2-C
- Histone H3.1t
- Histone H3.3
- Bromodomain-containing protein 4
- Histone H3.2
- Histone H3.1
- Histone acetyltransferase p300
- Histone H2A type 2-A
Sequence:
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG