wanglab/gogpt-training-data huggingface dataset:
Protein: Ribosome maturation protein SDO1 (Q07953)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with the EF-2-like GTPase RIA1, may trigger the GTP-dependent release of TIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating TIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14690591}. Nucleus.
Interaction partners:
- Eukaryotic translation initiation factor 6
- Ribosome assembly protein 1
- Restriction of telomere capping protein 3
- 60S ribosomal export protein NMD3
- 60S ribosome subunit biogenesis protein NIP7
- Large subunit GTPase 1
- Elongation factor 2
- Ribosome assembly factor MRT4
- Large ribosomal subunit protein uL16
- Nucleolar GTP-binding protein 1
Sequence:
MPINQPSGQIKLTNVSLVRLKKARKRFEVACYQNKVQDYRKGIEKDLDEVLQIHQVFMNVSKGLVANKEDLQKCFGTTNVDDVIEEIMHKGEIQLSEKERQLMLNKVNNEMLTIVSAKCINPVSKKRYPPTMIHKALQELKFSPVINKPAKLQALEAIKLLVSKQIIPIVRAKMKVKVAISEPSRQPELIEKISKLIASSPGESTKPELDPWTCTGLIDPVNYRDLMTLCDKKGTVQVLDMAVIDNTTHN
Protein: Pathogenesis-related protein 5 (PR-5) (P28493)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Partially responsible for acquired pathogen resistance.
Subcellular location: Secreted, extracellular space, apoplast. Note=Accumulates in the apoplast before secretion.
Interaction partners:
- Glucan endo-1,3-beta-glucosidase, acidic isoform
- Hevein-like preproprotein
- Pathogenesis-related protein 1
- Pathogenesis-related protein 1
- Regulatory protein NPR1
- Basic endochitinase B
- CAP superfamily protein
- Defensin-like protein 16
- Protein EDS1
- Lipase-like PAD4
Sequence:
MANISSIHILFLVFITSGIAVMATDFTLRNNCPTTVWAGTLAGQGPKLGDGGFELTPGASRQLTAPAGWSGRFWARTGCNFDASGNGRCVTGDCGGLRCNGGGVPPVTLAEFTLVGDGGKDFYDVSLVDGYNVKLGIRPSGGSGDCKYAGCVSDLNAACPDMLKVMDQNNVVACKSACERFNTDQYCCRGANDKPETCPPTDYSRIFKNACPDAYSYAYDDETSTFTCTGANYEITFCP
Protein: Bicarbonate-binding protein CmpA (P39660)
Organism: Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2)
Function: Part of the ABC transporter complex CmpABCD involved in bicarbonate transport. Binds bicarbonate with high affinity.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:2498292}; Peripheral membrane protein {ECO:0000269|PubMed:2498292}.
Interaction partners:
- Bicarbonate transport system permease protein CmpB
- Bicarbonate transport ATP-binding protein CmpD
- Bicarbonate transport ATP-binding protein CmpC
- Nitrate import ATP-binding protein NrtD
- Nitrate import permease protein NrtB
- MalK-like protein
- Integral membrane protein
Sequence:
MNEFQPVNRRQFLFTLGATAASAILLKGCGNPPSSSGGGTSSTTQPTAAGASDLEVKTIKLGYIPIFEAAPLIIGREKGFFAKYGLDVEVSKQASWAAARDNVILGSAGGGIDGGQWQMPMPALLTEGAISNGQKVPMYVLACLSTQGNGIAVSNQLKAQNLGLKLAPNRDFILNYPQTSGRKFKASYTFPNANQDFWIRYWFAAGGIDPDKDIELLTVPSAETLQNMRNGTIDCFSTGDPWPSRIAKDDIGYQAALTGQMWPYHPEEFLALRADWVDKHPKATLALLMGLMEAQQWCDQKANRAEMAKILSGRNFFNVPVSILQPILEGQIKVGADGKDLNNFDAGPLFWKSPRGSVSYPYKGLTLWFLVESIRWGFNKQVLPDIAAAQKLNDRVTREDLWQEAAKKLGVPAADIPTGSTRGTETFFDGITYNPDSPQAYLQSLKIKRA
Protein: FI21425p1 (Neuroligin) (Neuroligin 2, isoform B) (Neuroligin 2, isoform C) (Q9NGK5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Neurexin 1, isoform F
- Peripheral plasma membrane protein CASK
- Liprin-alpha, isoform E
Sequence:
MAQTKIIQSRFLHIYGLLCLGSLMGCIKTIGASIAQQTLADADAPDEAKAKEREAETDADADAEGDAKAETETGKGTREHTNGDAEADARIMATGICIIRLITLKRFLENSKTEEHNQRRQQSATSAASAAPAGATSPRRRHLHYPGHSAVQPGHPEACALLVLLLLTSLWPDCCECLHGGSNTVKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVKVDHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIPQLHRHFNINDQSMRHHQFQDDMNNRDLYEGVVRPQLQTKPAEDDNIIIMQRSRTTTPPPPSKNPSTNATQALNPLGTGTPTTTECGIDGAMSVSELTTTQSPKDNRTGIVRVETQKDLATASTGIIGNLELLRRLGGKQFQSYTTALIATVAVGCFLLILNVLIFAGIYHQREKRARDAKTKEELQEGDNSKNSSILKLNALMGGGGACGSGPGDIADAYTLSGSVVDSKGGVGVVFGEYSCYDEKTKQLKEEKLLVELPPSSSTGQTSLMIDNWGACSTSTLDLLKTKPGDPIEMVTYSALPSVMESTSAMSSKRGSFVDTTLQFNSPQQFDYAVQSSDQMSFKAIEDAVKAAAGHDSEITRDDDIPEPPPPPRSFLAAQQQQQQQQQQQQTGILRQTGAGGTSTSGSASGSGKKRVHIQEISV
Protein: PTS system mannitol-specific cryptic EIICB component (EIICB-Mtl) (EII-Mtl) [Includes: Mannitol permease IIC component (PTS system mannitol-specific EIIC component); Mannitol-specific phosphotransferase enzyme IIB component (EC 2.7.1.197) (PTS system mannitol-specific EIIB component)] (P69826)
Organism: Escherichia coli (strain K12)
Function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.
Subcellular location: Cell inner membrane {ECO:0000255|PROSITE-ProRule:PRU00427, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00427, ECO:0000269|PubMed:15919996}.
Interaction partners:
- Mannitol-specific cryptic phosphotransferase enzyme IIA component
- Mannitol-1-phosphate 5-dehydrogenase
- Multiphosphoryl transfer protein
- PTS system mannitol-specific EIICBA component
- Phosphocarrier protein HPr
- Uncharacterized protein YggP
- Hexitol phosphatase A
- Hexitol phosphatase B
- Fumarase E
- Fructose-1,6-bisphosphatase 2 class 2
Sequence:
MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWLPNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSMIMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANTFVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMVASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIAGGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLILKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFRKRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLDTLFNQLTAEHKH
Protein: Phospholipid N-methyltransferase protein (B9J8G0)
Organism: Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter)
Interaction partners:
- Phosphatidylcholine synthase
- Phosphatidylethanolamine N-methyltransferase/phosphatidyl-N-methylethanolamine N-methyltransferase protein
- Phosphatidylserine decarboxylase proenzyme
- phospholipase C
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- FAD-oxidoreductase protein
- Oxygen-dependent choline dehydrogenase
- Alcohol dehydrogenase protein
- FAD-dependent L-sorbose dehydrogenase protein
- Transcriptional regulator protein
Sequence:
MTTKTTCSDFVQFFRSWVSDPMRVAAIAPSGERLARLMTQEIEPLDGPVLELGPGTGVFTRALLARGVSECDLTLIEFGEEFVAPLRGRFPQARVVQMDAAQLGQCGLFADTPFGAVVSGLPLLSMPPEKIAAIVGGAFATMKPGGSFYQFTYGPRCPVPRLILDRLGLKATRVGGTVRNIPPAGVYRISRGKPLELSIDGSEYRSTNENAGIAAYAAEAGAADMGRPEAGA
Protein: 63 kDa globulin-like protein (allergen Ory s GLP63) (Q75GX9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Seed storage protein.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MATRARATILLLLAAVLFAAAAAASGEDRRRETSLRRCLQRCEQDRPPYERARCVQECKDQQQQQQERRREHGGHDDDRRDRDRRGEGSSEEEDEGRERGSRRRPYVFGRRSFRQVVRSDQGSVRLLPPFHQASSLLRGIKNYRVAVLEANPRSFVMPTHTDAHCICYVAQGEGVVAIIENGEKWSYAIRQGDVFVAPAGTINYLANTDGRRKLIVTKILHTISVPGQIQFFFAPGGRNPESFLSSFSKGVQRAAFKISEEKLEKLLGKQDKGVIIRASEEQVRELRRHASEGGHGPHWPLPPFGESSRGPFNILEQRPRFANRHGRLYEADARSFHDLAEHDIRVAVVNITAGSMNAPFYNTRSVKVAYVLDGEGEAEIVCPHLSRGGRGGESEERRRERGKGKWREEEEEEEEQQKGQEEEEEEQVGQGYETIRARLSRGTVFVVPSGHPIVVTSSRDSTLQIVCFDVHANNNERMYLAGMNSVLKKLDPQAKELAFAASAREVDELLNAQQESAFLAGPEKSGRRGEESEDEDRRRRRSHRGRGDEAVETLLRMAAAAV
Protein: Collagen, type IV, alpha 6 (B1AVK5)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
Interaction partners:
- Col4a5 protein
- Collagen alpha-3
- Collagen alpha-1
- Collagen alpha-4
- Collagen alpha-2
- CD44 antigen
- Platelet glycoprotein VI
- Integrin alpha-5
- Integrin alpha-1
- Collagen alpha-1
Sequence:
MHPGLWLFLVSLCLTKELAESGQKMSYGKPCGSRDCHGVCTCFPEKGARGHPGPIGTQGPAGPEGFTGPTGLSGLKGERGSPGPLGPYGSKGDKGPIGVPGFVGISGIPGHPGQPGPRGPPGPDGCNGTQGAVGFPGPDGYPGILGPPGLPGHKGAKGEPVPFQGSITGIRGDPGLPGLDGIPGPSGSSGSPGDAGPIGPPGLQGPPGLPGLPGPEGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPPGFPGMSGPPGVPEFGSTGEKGEKGILGLPGPRGPMGSEGIQGHPGRQGKKGTSGFPGINGFPGIKGEKGDIGVRGPDSFTDADGAVISGYPGDPGVLGLPGLRGDEGVQGQRGPSGTPGLPSLTGLPGALGPQGFPGLKGDQGNSGRTTFGEAGLPGRVGLPGLPGLPGPSGPPGRTFETGHLSNIEPGFPGLQGEQGPKGHQGLKGVKGDSGFCACEGGAPNIGPHGEPGLPGIQGPIGLQGFKGTKGDPGSRGASGPAGTPGLFGPRGQTGLKGKKGEPTVSRGSKMSGDKGDPGPQGTPGLAGTPGKDGRPGLPGLPGIQGDGGSGFPGERGLPGLPGEKGHDGPIGPPGIGLPGPPGPRGLPGDKGVDGLPGQQGLRGAQGVTLPCIIPGSYGPSGFPGAPGFPGSKGARGLPGIPGKPGTHGSKGGPGSPGLMHLPGLPGFPGVRGEKGLPGFPGLPGKDGYPGKAGSPGLPGFKGAAGDIFGAENGASGEQGLQGLPGDKGFPGDSGLPGPKGLNGKPGMLGPKGERGNPGTSGPPGQPGPSGSTDPFGIKGTSGFPGAPGLPGISGHPGKKGQRGDIGQPGSTGKRGLPGIKGLPGPQGSPGFLGSPGLSGVTGLPGIEGQKGEKGSSGPVGFPGLPGLPGLPGADGLKGFSGSFGKVGQPGQTGTSGEKGDRGDPGPVGISSPRPPMLNLWFKGEKGSRGSAGSDGFPGPRGDKGEPGIPGLPGPPGATGQTNTIKGLNGRPGSPGSMGRRGLPGLKGSLGIAGFPGMPGKSGSQGLTGTSGLLGATGIPGLKGDQGQTLGISGSPGPKGQPGELGFKGVKGKDGLVGDRGYPGNKGDGGKVGITGDPGFPGSPGLQGISGMNGDPGLPGSSGHLGSIGRPGPSGLIGPKGFPGAPGLHGLNGLPGTKGTHGTPGASITGVPGPAGLPGPKGERGVPGIVIGDPGKQGSKGQKGDQGSPGLQGPAGTPGAPGISLPSVIAGQPGDPGRPGLDGERGRPGPPGPPGPPGPSSDQGDPGDSGFPGIPGLQGFKGNQGLPGFSGLSGELGLKGMRGEPGLMGTPGKIGQPGDPGFPGMKGKAGPRGFSGPQGAPGHTPIAEAMQVPPGPLGLPGIDGIPGLIGDPGSQGSVGLQGSKGLPGIPGKDGPSGLPGPSGILGDPGLPGLQGPPGFEGAPGNQGPIGQPGMPGHGVRVGYTLVKHSQSEQVPLCPTGMSRLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPMMPVGQTQIPQYISRCSVCEAPSQAIAVHSQDIIVPQCPLGWHSLWIGYSFLMHTAAGAEGGGQSLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERGQFREEPVSETLKTGQLHTRVSRCQVCMKTP
Protein: DASH complex subunit DAD4 (DUO1 and DAM1-interacting protein 4) (Helper of ASK1 protein 2) (Outer kinetochore protein DAD4) (P69851)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B. Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:14562095}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:14562095}. Note=Associates with the mitotic spindle and the kinetochore.
Interaction partners:
- DASH complex subunit DAD2
- DASH complex subunit SPC34
- DASH complex subunit DUO1
- DASH complex subunit DAD3
- DASH complex subunit SPC19
- DASH complex subunit ASK1
- DASH complex subunit DAD1
- DASH complex subunit HSK3
- DASH complex subunit DAM1
- Glycine cleavage system H protein, mitochondrial
Sequence:
MENPHEQVQANILSRIIGNVKRLNESVAILNQELVTINNRNKNLEIMGAICDNYHSSVQFNLEATNNKKPPL
Protein: Protein TIS11 (dTIS11) (P47980)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Not1, isoform H
- 5'-3' exoribonuclease 1
- Transportin-1
- MAP kinase-activated protein kinase 2
- poly
- m7GpppN-mRNA hydrolase
- RAC serine/threonine-protein kinase
- CCR4-NOT transcription complex subunit 9
- Enhancer of mRNA-decapping protein 3
- ATP-dependent RNA helicase me31b
Sequence:
MSADILQKSREQDDSHYFERGDISKYVTMNDHLGDFDCNEVRKEIRMLLAHGANLDQQHQQQPHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNADEARAQQAAQAAKSSTQSQSQSQQSSSQNFSPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPLSMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMGHHGPATPPESPNVPISPVHTPPPYDVVVSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLSSGVEAYQQQSNLGL
Protein: Actin-like protein, putative (Q38C43)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RuvB-like helicase
- RuvB-like helicase
- SNF2 DNA repair protein, putative
- Cofilin/actin depolymerizing factor, putative
- Uncharacterized protein
Sequence:
MLAVTARRATMLVGCYSRHWCLPYVRVVTTNSFCFVLFFYKFFFFVFCRMTAGYPVLVVDNGGYMLKALYITSDGKSSFLRGKIAVIPNCVGAASYVGRGIVGEQLFKLPHFHGFMVRRPVDRGFIVDAGLQSYIWEYLLQHLAVADESEVELVMTVPFGAPKQVGELLHYLVAQRFRFRSVTFVSSSFLTLVSSVSRDWLYGKAPGNGKSNKKVREKSNFGSDGVGSESVTGCGMVVDFGFSSTTVVPYVNFIPLQDSIVRIDVGGKLLSNRLKELISFTQVNVTEDGWLVNHIMEQACYVALDPLVSLRKAEYAKRFDKGNGAFAGLRYYLPTVPPLMPLGCREEQLTQIIGKDVVLQEKNSLQHIVFRHEAFLIPELIFNPVDVGICQMGVVEAIVHGTCCRGSLQNMRTLHGAMMRRIIAFGGITKFKNLPERLSTELRKHLKEEGASRVSVPPVKGSAPLQEFVQWSRIGRVRIDLQYNGVGYTPSDCELQPLFGALALITCPVLEPQLKLVQSRSRVELLPGSTAKGSQNRQQASAGPRTLSAVLSALQNLL
Protein: Vesicle-associated membrane protein 2 (Q2MK74)
Organism: Scophthalmus maximus (Turbot) (Psetta maxima)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00046280}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00046280}.
Interaction partners:
Sequence:
MSAPAGAPAPDGGNQPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKNKYWWKNAKMMIILGVICVIVLIVIIVYFST
Protein: GMP/IMP nucleotidase YrfG (EC 3.1.3.5) (P64636)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the dephosphorylation of different purine nucleotides (GMP and IMP). Also hydrolyzes flavin mononucleotide (FMN).
Interaction partners:
- Pyrimidine 5'-nucleotidase YjjG
- 5'-deoxynucleotidase YfbR
- 5'/3'-nucleotidase SurE
- Heat shock protein 15
- Protein UshA
- dITP/XTP pyrophosphatase
- Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase
- GMP synthase
- Pyrimidine/purine nucleoside phosphorylase
- Purine nucleoside phosphorylase 2
Sequence:
MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNGVTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFLEALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAEATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLIPSLM
Protein: Oligo-1,6-glucosidase IMA5 (EC 3.2.1.10) (Alpha-glucosidase) (Isomaltase 5) (P40884)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Alpha-glucosidase with specificity for isomaltose, maltose, and palatinose.
Interaction partners:
- Invertase 2
- Glucoamylase, intracellular sporulation-specific
- General alpha-glucoside permease
- Maltose fermentation regulatory protein MAL13
- Maltose permease MAL31
- Maltose fermentation regulatory protein MAL33
Sequence:
MTIIHNPKWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYEKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYWLRHNVDGFRIDVGSMYSKVEGLPDAPITDPTVPYQKGTEFFINGPRIHEYHKEMHNYMLSQVPEGKEIMTVGEVGIGNEDDFRVYTSAKEGELNMMFNFKHTSVGENPKCKYELIPFTLKDFKLALAESFLFIENTDCWSTIYLENHDQPRSVSRFGSDSPKWREISSKMLATLIISLTGTVFIYQGQELGMPNFKNRKIEQIKCVEGTGTYAAIKRDYGEDSEKMKKFFEALALISRDHGRTPFPWSADEPSAGFSKDAKPWIDMNESFRDGINAEAELKDKNSVFFFWKKALQVRKEHKDILVYGHNFQFIDLDNDKLFMFTKDTDNKKMFAVFNFSSDNTDFSVPDNEASYTMFFGNYANSNGDSRTLQPWEGRLYLLK
Protein: Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E) (P52952)
Organism: Homo sapiens (Human)
Function: Transcription factor required for the development of the heart and the spleen. During heart development, acts as a transcriptional activator of NPPA/ANF in cooperation with GATA4 (By similarity). May cooperate with TBX2 to negatively modulate expression of NPPA/ANF in the atrioventricular canal (By similarity). Binds to the core DNA motif of NPPA promoter. Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression. Positively regulates transcription of genes such as COL3A1 and MMP2, resulting in increased pulmonary endothelial fibrosis in response to hypoxia.
Subcellular location: Nucleus {ECO:0000269|PubMed:29899023}.
Interaction partners:
- Transcription factor GATA-4
- T-box transcription factor TBX5
- T-box transcription factor TBX20
- Myocyte-specific enhancer factor 2C
- Heart- and neural crest derivatives-expressed protein 2
- Serum response factor
- Natriuretic peptides A
- Myocyte-specific enhancer factor 2B
- Histone-lysine N-methyltransferase NSD2
- Myocyte-specific enhancer factor 2A
Sequence:
MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
Protein: Metabotropic GABA-B receptor subtype 2 (Q9BML6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MFRPSWFPFASLLFLLLWSTACGRTAKRSDVYIAGFFPYGDGVENSYTGRGVMPSVKLALGHVNEHGKILANYRLHMWWNDTQCNAAVGVKSFFDMMHSGPNKVMLFGAACTHVTDPIAKASKHWHLTQLSYADTHPMFTKDAFPNFFRVVPSENAFNAPRLALLKEFNWTRVGTVYQNEPRYSLPHNHMVADLDAMEVEVVETQSFVNDVAESLKKLREKDVRIILGNFNEHFARKAFCEAYKLDMYGRAYQWLIMATYSTDWWNVTQDSECSVEEIATALEGAILVDLLPLSTSGDITVAGITADEYLVEYDRLRGTEYSRFHGYTYDGIWAAALAIQYVAEKREDLLTHFDYRVKDWESVFLEALRNTSFEGVTGPVRFYNNERKANILINQFQLGQMEKIGEYHSQKSHLDLSLGKPVKWVGKTPPKDRTLIYIEHSQVNPTIYIVSASASVIGVIIATVFLAFNIKYRNQRYIKMSSPHLNNLIIVGCMITYLSIIFLGLDTTLSSVAAFPYICTARAWILMAGFSLSFGAMFSKTWRVHSIFTDLKLNKKVIKDYQLFMVVGVLLAIDIAIITTWQIADPFYRETKQLEPLHHENIDDVLVIPENEYCQSEHMTIFVSIIYAYKGLLLVFGAFLAWETRHVSIPALNDSKHIGFSVYNVFITCLAGAAISLVLSDRKDLVFVLLSFFIIFCTTATLCLVFVPKLVELKRNPQGVVDKRVRATLRPMSKNGRRDSSVCELEQRLRDVKNTNCRFRKALMEKENELQALIRKLGPEARKWIDGVTCTGGSNVGSELEPILNDDIVRLSAPPVRREMPSTTVTEMTSVDSVTSTHVEMDNSFVSVQSTVMAPSLPPKKKKQSIVEHHSHAPAPTMMQPIQQQLQQHLQQHQQMQQQHLQQQQHQQMQQQQQQQQHHHRHLEKRNSVSAQTDDNIGSITSTAGKRSGGDCSSMRERRQSTASRHYDSGSQTPTARPKYSSSHRNSSTNISTSQSELSNMCPHSKPSTPAVIKTPTASDHRRTSMGSALKSNFVVSQSDLWDTHTLSHAKQRQSPRNYASPQRCAEHHGGHGMTYDPNTTSPIQRSVSEKNRNKHRPKPQKGTVCQSETDSERERDPPPNSQPCVQPRKVSRSSNIQHAAHHHSSPNVAPDKQRSRQRGKQDSSIYGASSETELLEGETAILPIFRKLLTEKSPNYRGRSAVGQSCPNISIKCDIVEYL
Protein: Meiotic driver wtf35 (A0A482ARP7)
Organism: Schizosaccharomyces pombe (Fission yeast)
Function: Promotes unequal transmission of alleles from the parental zygote to progeny spores by acting as poison/antidote system where the poison and antidote proteins are produced from the same locus; the poison component is trans-acting and targets all spores within an ascus whereas the antidote component is spore-specific, leading to poisoning of all progeny that do not inherit the allele.
Subcellular location: [Isoform 1]: Spore membrane {ECO:0000255, ECO:0000269|PubMed:32032353}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. {ECO:0000250|UniProtKB:A0A218N034}.; SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm {ECO:0000250|UniProtKB:A0A218N034}. Cytoplasm {ECO:0000250|UniProtKB:A0A218N034}. Spore membrane {ECO:0000255, ECO:0000269|PubMed:32032353}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A0A218N034, ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1. {ECO:0000250|UniProtKB:A0A218N034}.
Interaction partners:
Sequence:
MKNKDYPLRTSMDELSTKNDNEIDLEKGPLPEYNSEDGSTLPPYSDLNNPKQMGQNITKLFNWNKSTTPPDYDENRLPITDEGNNPPNTHRENHSSGTTDNSSPFLIKLLISFTSIILFNAPAVCYLKYKDAFFKNYGAAEWTLIGFWCASSLIIFTFSWYFYETWTKAVGKGIKHFLKKWRNIPMAFSEVFLFNILVGSPRVALRHISGERWGLKCSLADHIIFAILSILVFIVETVEPGSSKINIMKRLRGDNARDATQHVNEYTAVPLREMNPESEA
Protein: Skp1-related protein (Q9XU27)
Organism: Caenorhabditis elegans
Interaction partners:
- Cullin-6
- Cullin-1
- RING-box protein 1
- F-box/WD repeat-containing protein lin-23
- DUF305 domain-containing protein
- RING-type domain-containing protein
Sequence:
MSSEEQDVKIVTSDDVEFIVSPKIANQSKLLADFVVLNQREPIPLKNVTSEIFKKVIEWCEYHAEDIPKPPDNVEEKRTDDIGEWDVEFLKVDKGTLFELVLAATYLDIKGLFNVTCKSIANSIKGKSPEEIRAVFNLGNETNME
Protein: CASP-like protein 2A2 (AtCASPL2A2) (Q9LUL1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in floral organ shedding.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- CASP-like protein 5C3
- CASP-like protein 1D2
- Cytochrome P450 71B31
- Calcium-dependent protein kinase 25
- Polygalacturonase 1 beta-like protein 3
- Protein GRIM REAPER
- Polygalacturonase ADPG2
- Transcription factor MYB57
- 2-oxoglutarate
- UMP kinase
Sequence:
MDKTDQTAIDESALVLNRTEKSAEAVLRVASMALSITGLVIMIKNSISNEFGSVSYSNIGAFMYLVSANGVCAAYSLLSALAILALPCPISKVQVRTLFLLDQVVTYVVLAAGAVSAETVYLAYYGNIPITWSSACDSYGSFCHNALISVVFTFVVSLLYMLLSLISSYRLFTRFEAP
Protein: Nuclear pore complex protein An-Ndc1 (Eurofung) (C8V8S4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Nucleus membrane {ECO:0000256|ARBA:ARBA00004232}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004232}. Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
- Nuclear pore complex protein An-Pom152
- Uncharacterized protein
Sequence:
MAAKPRPYRRILTSALHRRFVHASALSLLVCYAISVLIGDKSSLFWALFPLGSCGIRTILLFISPLAIFVLRVGQMHIGSRTTSSSLNTFHYLFPLHVIQTFGWYIFSAWWFSELYKWSAPTSAHLEWVKRGSPHERATLNERTIYIYTYHLLLAIAQSLAHLYNDYDRVPIAITDKPVGGADQKTHPTQPISKRLQEGLHQTLRDGLFRSTVVALVCPVAYVFFLRRRAWTYTMSFAKLFWDFPRSAADPPSLILPVKPPLIARTIFSGALLVLCWQTTNLFFSMFLSQEPVKRGQPLTSGAKDPTGSLLNGLKAKKETVRAFAFWELCFISQQFPDRRKAIFNDIDREGGSAWTQIMQSATEVIQGITSRINEQKLGPAKSKPSPAETKSEPTLRTLPRLTDPVKEGNIFAASPRSTTTNGRLGEGFSSTLRSLGESPDWTPKARARARDVFDRASSAVLSPERKQKLLSSSQDFKLLTGASSTRPESIHPFLAQLLRSPIGLLIRQPFARRLSGIVLGTPTASLSSIIDAIESITRLLIASLNEDPYGKVQADVPAIVSLFTETLTTLDTYAHVELDVHWTDAAFPPSNDPAAQAAARRVPDVELIIDSLRASLKSLLTAFSPYFKDVGLVGKELRLAKGAAGFDEE
Protein: Rho-related GTP-binding protein RhoD (P97348)
Organism: Mus musculus (Mouse)
Function: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution.
Subcellular location: Cell membrane. Early endosome {ECO:0000269|PubMed:24102721}. Note=Colocalizes with RAB5 to early endosomes. {ECO:0000269|PubMed:24102721}.
Interaction partners:
- Plexin-A1
- Rho-related GTP-binding protein Rho6
- Plexin-A4
- Plexin-A3
- Plexin-A2
- Plexin-B1
- Plexin-B2
- Protein diaphanous homolog 2
- Intersectin-2
- Intersectin-1
Sequence:
MNASQVAGEEAPQSGHSVKVVLVGDGGCGKTSLMMVFAKGAFPESYSPTVFERYNATLQMKGKPVHLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDVTNPNSFDNVSNRWYPEVTHFCKGVPIIVVGCKIDLRKDKVLVNNLRKKRLEPVTYHRGHDMARSVGAVAYLECSARLHDNVEAVFQEAAEVALSSRRHNFWRRITQNCCLAT