wanglab/gogpt-training-data huggingface dataset:
Protein: StAR related lipid transfer domain containing 3 (J3QLM1)
Organism: Homo sapiens (Human)
Subcellular location: Late endosome membrane {ECO:0000256|ARBA:ARBA00004107}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004107}.
Interaction partners:
Sequence:
MSKLPRELTRDLERSLPAVASLGSSLSHSQSLSSHLLPPPEKRRAISDVRRTFCLFVTFDLLFISLLWIIELNVLAFFRFSGLLLGYAVLRLRHWWVIAVTTLVSSAFLIVKVILSELLSKGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQVAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLISYDVSAGAAGGVVSPRDFVNVRRIERRRDRYLSSGIATSHSAKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKVGCWGAARAACPGTSSTRASRPPCLNLPFTCDSASASWGPGRDCAPSHPAGQGPVATTSRARKGASWARTAHMGPGPRLSPSTEPRSAWS
Protein: Tryptophan synthase beta chain (EC 4.2.1.20) (P0A2K1)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
Interaction partners:
- Tryptophan synthase alpha chain
- Anthranilate synthase component 1
- Tryptophan biosynthesis protein TrpCF
- Bifunctional protein TrpGD
- Aminodeoxychorismate synthase component 1
- Aminodeoxychorismate synthase component 2
- L-Threonine dehydratase biosynthetic IlvA
- Serine hydroxymethyltransferase
- L-threonine dehydratase catabolic TdcB
- Phosphoserine phosphatase
Sequence:
MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
Protein: RPTOR independent companion of MTOR, complex 2 (A0A8I5ZNG4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTDEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYASLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKVLTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQSIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHSWDSVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFILEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPTKKHRSSSDPKGGKLSSENKTSNRRIRTFTEPSVDFNHSDDFTNISPAQKTLQLETSFVGNKHLEDTGSTPSIGDNDLKFPKSFGPENHRENTSRERLVVESSAGSHMKIRSQSFNTDTTTSGISSMSSSPSRETVAVDSTTMDTDCGSLSTVVSTKTVKTSHYLTPQANHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTIANNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQSKHVPPPDDRGARTFSHDGGGLPSGTGSLVKNSFHLLRQQMSLTEIMNSVHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSSICSHSDLQDIPYSDWCEQPIHNPLEVVPSKFSGISGCSDGASQEEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAIPPNQPIVDESAES
Protein: Bromodomain containing 8 (A0A8I5XUT9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MRKGQLTLSLKSALCPVLFGFEVASPCVDEQPHVHGLKTYTLMLLQRVNLCSVSGTPEVWPLWGLSTVISFRVVPGSNSGCRAFRTRVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLKRDAELIQAGHMDSRLDELCSDIAMKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVNESEMPVPSGHLSSTGVLLEVGGVLPMIHGGDIQPATSAVAASPAASGAPTLSRLLEAGPTQFSTPLPSFTTVASEPPVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTPESVAPVSQPEPCVPLEAVGDPQTVTVSMDSSEISMIINSIKEECFRSGVAEAPGGSKAPSIDGKEDLDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEESETKGIHELVDIRDSGVEIKVEPTEPEPGMSGAEIVAGVGPVPSLEPPELRSQDLDEEPRSSAAGEMGEADGSSGKGEERPLPAVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEEEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLGDSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFDGGTRGRRCAIEADMKMKK
Protein: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7) (Spermatogenesis cell proliferation-related protein) (Spermatogenesis-associated protein 11) (Q9BT30)
Organism: Homo sapiens (Human)
Function: May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate. Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity. Involved in fatty acid metabolism (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:23666923}.
Interaction partners:
- Nucleic acid dioxygenase ALKBH1
- Probable RNA/DNA demethylase ALKBH6
- 2-oxoglutarate and iron-dependent oxygenase JMJD4
- Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4
- tRNA
- DNA oxidative demethylase ALKBH2
Sequence:
MAGTGLLALRTLPGPSWVRGSGPSVLSRLQDAAVVRPGFLSTAEEETLSRELEPELRRRRYEYDHWDAAIHGFRETEKSRWSEASRAILQRVQAAAFGPGQTLLSSVHVLDLEARGYIKPHVDSIKFCGATIAGLSLLSPSVMRLVHTQEPGEWLELLLEPGSLYILRGSARYDFSHEILRDEESFFGERRIPRGRRISVICRSLPEGMGPGESGQPPPAC
Protein: Ribonucleoside-diphosphate reductase (EC 1.17.4.1) (Q0ILH2)
Organism: Enterobacteria phage T6 (Bacteriophage T6)
Interaction partners:
Sequence:
MQLINVIKSSGVSQSFDPQKIIKVLSWAAEGTSVDPYELYENIKSYLRDGMTTDDIQTIVIKAAANSISVEEPDYQYVAARCLMFALRKHVYGQYEPRSFIDHISYCVNEGKYDPELLSKYSAEEITFLESKIKHERDMEFTYSGAMQLKEKYLVKDKTTGQIYETPQFAFMTIGMALHQDEPVDRLKHVIRFYEAVSTRQISLPTPIMAGCRTPTRQFSSCVVIEAGDSLKSINKASASIVEYISKRAGIGINVGMIRAEGSKIGMGEVRHTGVIPFWKHFQTAVKSCSQGGIRGGAATAYYPIWHLEVENLLVLKNNKGVEENRIRHMDYGVQLNDLMMERFGKNDYITLFSPHEMGGELYYSYFKDQDRFRELYEAAEKDPNIRKKRIKARELFELLMTERSGTARIYVQFIDNTNNYTPFIREKAPIRQSNLCCEIAIPTNDVNSPDAEIGLCTLSAFVLDNFDWQDQDKINELAEVQVRALDNLLDYQGYPVPEAEKAKKRRNLGVGVTNYAAWLASNFASYEDANDLTHELFERLQYGLIKASIKLAKEKGPCEYYSDTRWSRGELPIDWYNKKIDQIAAPKYVCDWSSLREDLKLFGIRNSTLSALMPCESSSQVSNSTNGIEPPRGPVSVKESKEGSFNQVVPNIEHNIDLYDYTWKLAKKGNKPYLTQVAIMLKWVCQSASANTYYDPQIFPKGKVPMSIMIDDMLYGWYYGIKNFYYHNTRDGSGTDDYEIETPKADDCAACKL
Protein: Fibromodulin (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin) (P13605)
Organism: Bos taurus (Bovine)
Function: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- Transforming growth factor beta-1 proprotein
- Aggrecan core protein
- Transforming growth factor beta
- Biglycan
- Lumican
- Decorin
- SPARC
- Mimecan
- Collagen alpha-1
- Collagen alpha-1
Sequence:
MQWASILLLAGLCSLSWAQYEEDSHWWFQFLRNQQSTYDDPYDPYPYEPYEPYPYGGEEGPAYAYGSPPQPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQISSIQEGVFDNATGLLWIALHGNQITSDKVGKKVFSKLRHLERLYLDHNNLTRIPSPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQEVGSSMKGLRSLILLDLSYNHLRKVPDGLPSALEQLYLEHNNVFSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVSTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI
Protein: Large ribosomal subunit protein uL14c (50S ribosomal protein L14, chloroplastic) (Q6END7)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: Binds to 23S rRNA.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL2 C-terminal domain-containing protein
- Small ribosomal subunit protein uS8c
- Large ribosomal subunit protein uL4 C-terminal domain-containing protein
- Large ribosomal subunit protein uL3c
- Large ribosomal subunit protein uL22c
- Large ribosomal subunit protein uL5c
- 60S acidic ribosomal protein P1
- Small ribosomal subunit protein eS31 domain-containing protein
- Large ribosomal subunit protein uL16c
- 50S ribosomal protein L22
Sequence:
MIQPQTLLNVADNSGARKLMCIRVIGAASNQRYARIGDVIVAVIKDAVPQMPLERSEVIRAVIVRTCKEFKCEDGIIIRYDDNAAVIIDQKGNPKGTRVFGAIAEELRELNFTKIVSLAPEVL
Protein: TNF receptor associated factor 7 (A0A8I5ZTK4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSSAKSARYNRFSGGPANLPASDSSGTRMETTFGPTFSTVTTITKAADGTSTYKQHRRTPSSSSTLAYSPRDEEDGMEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKSEKCPVDNAKLTVVVNNIAVAEQIGELFIHCRHGCRAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRPVRCPNNPSCPPLLKMNLEAHLKECEHIKCPHSKCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLNDELSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHNMLFSGSLKAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSGSYQTIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGAVDSTVKVWTC
Protein: High mobility group protein D (HMG-D) (Q05783)
Organism: Drosophila melanogaster (Fruit fly)
Function: Binds preferentially single-stranded DNA and unwinds double-stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H1
Sequence:
MSDKPKRPLSAYMLWLNSARESIKRENPGIKVTEVAKRGGELWRAMKDKSEWEAKAAKAKDDYDRAVKEFEANGGSSAANGGGAKKRAKPAKKVAKKSKKEESDEDDDDESE
Protein: Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (UFM1-activating enzyme) (Q9VYY3)
Organism: Drosophila melanogaster (Fruit fly)
Function: E1-like enzyme which activates UFM1.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9GZZ9}. Nucleus {ECO:0000250|UniProtKB:Q9GZZ9}. Golgi apparatus {ECO:0000250|UniProtKB:Q9GZZ9}.
Interaction partners:
- Ubiquitin-fold modifier-conjugating enzyme 1
- Ubiquitin-fold modifier 1
- Molybdopterin synthase catalytic subunit
- E3 UFM1-protein ligase 1 homolog
- Adenylyltransferase and sulfurtransferase MOCS3
- Probable Ufm1-specific protease 2
- Probable Ufm1-specific protease 1
- Nedd8-conjugating enzyme UbcE2M
- E1 ubiquitin-activating enzyme
- Nedd8-activating enzyme E1 catalytic subunit
Sequence:
MSHAIDELQAIIADLKTELETEPKSSGGVASNSRLARDRIDRMSAEVVDSNPYSRLMALQRMNIVKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVAAAAATLSFINPDVEIETHNYNITTVENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINAACNERNLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLGYNALSDFFPKMTLKPNPQCDDRNCLVRQKEFQARPKPVLIEEKAVSEEPLHATNEWGIELVAEDAPESNTTPAETPVMGEGLRLAYEAPEKSSETSEETVSAATADETSLEDLMAQMKSM
Protein: Nucleotide exchange factor SIL1 (Q9EPK6)
Organism: Mus musculus (Mouse)
Function: Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000269|PubMed:16116427}.
Interaction partners:
- Hypoxia up-regulated protein 1
- Ubiquitin-like protein FUBI
- Endoplasmic reticulum chaperone BiP
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein bL12m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS17
- Elongation factor Tu, mitochondrial
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein bL17m
Sequence:
MAPQHLPSTRMASPGMLLGLLLTSCLTLCLSCQNSNNFALTNPEKSIHQESDTKETREEEELDTEILEVFHPTQEWQTLQPGQAVPAGSHVRMNLQTGVNEVKLQQEDKFQNNLKGFKRGRRLDINANTYTSQDLKSALAKFKEGTEMENSKDELARQATVKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSSSSLEEKVAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATNQPLPAKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKVLAVRVVTLLYDLVTEKMFAEEEAELTQDSSPEKLQQYRQVQLLPGLQEQGWCEITAQLLALPEHDAREKVLQTLGALLTTCRDRYRQDLQLSRTLGRLQAEYQALASLELQEGEDDGYFRELLASINSLMKELR
Protein: LD07294p (Two A-associated protein of 42kDa) (Q9VJZ5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Serine/threonine-protein phosphatase PP2A
- Serine/threonine-protein phosphatase 4 catalytic subunit
- Serine/threonine-protein phosphatase 6 catalytic subunit
- Protein LST8 homolog
- Serine/threonine-protein phosphatase
- Raptor, isoform B
- Serine/threonine-protein kinase mTor
- Serine/threonine-protein phosphatase 4 regulatory subunit 2
- MIP22305p
- Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit
Sequence:
MAEGNTAGGEDQKLTDIFLKGWNIFDELEVTELPFNGSEFQNKVKTAMGLFEQATVIVNQVSMFSANELIDEVSTESLPFMLLPYFLGKLTTKINSPNNTHSIELGEIYFKDHLQRCQEYDLCAAPKSQVAKADSQAEKSEQRELVEAAFNRNDKIAQYRRMKEIDEYMARMRDAVKNKTVDDEDKRVFFLKYLDKSIIDSKQELETLGVMKQLAQMRLARLAGGESDNEVDSFRPPNQNQSSASSTSRGHGHSHGPGHHHHHQQAAKPKPLQPFIITRNATQKAVFGLGYPSLPIMTVDEFYQQRVDEGIFPDEEKVAKMNQAQAIAAARDPNEKEDEEKAVEELQAEQDDPEYIDRMRRMDEYKDVVRRGDGNRHNRS
Protein: Single-strand annealing weakened protein 1 (P39735)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes 3'-non-homologous tail removal of RAD1/RAD10-dependent single-strand annealing recombination intermediates. Plays a key role in targeting RAD1/RAD10 complex to 3'-flap cleavage substrate in recombination. Also contributes to the integrity of ribosomal DNA arrays.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- DNA repair protein RAD1
- DNA repair protein RAD10
- DNA mismatch repair protein MSH2
- DNA mismatch repair protein MSH3
- Structure-specific endonuclease subunit SLX4
- DNA repair and recombination protein RAD52
- Structure-specific endonuclease subunit SLX1
- DNA repair protein RAD14
Sequence:
MAPSIATVKIARDMVLPLRIFVNRKQILQTNDKTSNKSNATIFEAPLLSNNSIICLKSPNTRIYLSQQDKKNLCDEIKEDLLLIVYELASPEIISSVLSKIRVGHSTDFQINVLPKLFAGADTDNAVTSHIQSVTRLAKFKYKLHYKHKWELDIFINSIKKIANLRHYLMFQTLTLNGFSLNAGPKTLLARKIEKQPQVPNLLIENGDADALDTPVEEDIKPVIEFMYKPVINLGEIIDVHVLHRPRRHKVRTQSKQPQEE
Protein: RNA-binding protein 43 (RNA-binding motif protein 43) (Q6ZSC3)
Organism: Homo sapiens (Human)
Interaction partners:
- Rho-related GTP-binding protein RhoE
Sequence:
MASVLNVKESKAPERTVVVAGLPVDLFSDQLLAVLVKSHFQDIKNEGGDVEDVIYPTRTKGVAYVIFKEKKVAENVIRQKKHWLARKTRHAELTVSLRVSHFGDKIFSSVNAILDLSVFGKEVTLETLVKDLKKKIPSLSFSPLKPNGRISVEGSFLAVKRLRESLLARACSLLEKDRNFTSEERKWNRQNPQRNLQRSNNSLASVRTLVPETARSGEMLVLDTDVFLYLKHKCGSYESTLKKFHILSQEKVDGEITTICLKSIQVGSQPNNAKHVKELIEEWSHALYLKLRKETFILEGKENREKRMIKRACEQLSSRYLEVLINLYRTHIDIIGSSSDTYLFKKGVMKLIGQKVS
Protein: Katanin regulatory subunit B1 like 1 (H0YNW3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MANKENELACAGHLPEKLHHDSRTYLVNSSDSGSSQTESPSSKYSGFFSEVSQDHETMAQVLFSRNMRLNVALTFWRKRSISELVAYLLRIEDLGVVVDCLPVLTNCLQEEKQYISLGCCVDLLPL
Protein: Dacapo (RE12958p) (Q7JNL9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- G1/S-specific cyclin-E
- Cyclin-dependent kinase 2
- Cyclin D, isoform D
- G2/mitotic-specific cyclin-A
- S-phase kinase-associated protein 2
- cyclin-dependent kinase
- Retinoblastoma family protein
- RAC serine/threonine-protein kinase
- Transcription factor E2f1
- Cullin homolog 1
Sequence:
MVSARVLNPVMISEFCKMSSSPAVSRNLACGRQLNRIKRDLFGSSKSAEGTANKTPFNSELERHQELATQKWGFDFRAGCPLAEKSPYIWERVSFQESSFAPEMYTLTRAAHVRPSADASPSDMDILVNERSERENFGSNLVNSSLESNTDNESCYDSQDESLAMRLSSSSTTSTSSIVLRKRQPKITEFMKERKRLAQAPKKLSPAKRMRTSSPSSSATSSSSSSGGFGLGAHFGAMLKRPRHN
Protein: Heme transporter HRG1 (Heme-responsive gene 1 protein homolog) (HRG-1) (hHRG-1) (Solute carrier family 48 member 1) (Q6P1K1)
Organism: Homo sapiens (Human)
Function: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
Subcellular location: Endosome membrane {ECO:0000269|PubMed:18418376, ECO:0000269|PubMed:23395172}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}. Lysosome membrane {ECO:0000269|PubMed:18418376, ECO:0000269|PubMed:23395172}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:Q9D8M3}; Multi-pass membrane protein {ECO:0000255}. Note=In macrophages, specifically localizes to the phagolysosomal membranes during erythrophagocytosis. {ECO:0000250|UniProtKB:Q9D8M3}.
Interaction partners:
- Choline/ethanolamine transporter FLVCR1
Sequence:
MAPSRLQLGLRAAYSGISSVAGFSIFLVWTVVYRQPGTAAMGGLAGVLALWVLVTHVMYMQDYWRTWLKGLRGFFFVGVLFSAVSIAAFCTFLVLAITRHQSLTDPTSYYLSSVWSFISFKWAFLLSLYAHRYRADFADISILSDF
Protein: Glutamine-binding periplasmic protein (GlnBP) (P0AEQ3)
Organism: Escherichia coli (strain K12)
Function: Involved in a glutamine-transport system GlnHPQ.
Subcellular location: Periplasm {ECO:0000305|PubMed:3027504}.
Interaction partners:
- Glutamine transport ATP-binding protein GlnQ
- Glutamine transport system permease protein GlnP
- Glutamate/aspartate import permease protein GltK
- Arginine ABC transporter permease protein ArtM
- L-cystine transport system permease protein TcyL
- Histidine/lysine/arginine/ornithine transport system permease protein HisM
- Glutamate/aspartate import permease protein GltJ
- Histidine/lysine/arginine/ornithine transport system permease protein HisQ
- Arginine ABC transporter permease protein ArtQ
- Inner membrane amino-acid ABC transporter permease protein YhdY
Sequence:
MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGDKYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPNIDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWFGTEPK
Protein: ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Caseinolytic mitochondrial matrix peptidase proteolytic subunit) (Endopeptidase Clp) (O88696)
Organism: Mus musculus (Mouse)
Function: Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:10754102, ECO:0000269|PubMed:22710082}.
Interaction partners:
- ATP-dependent clpX-like chaperone, mitochondrial
- Mitochondrial disaggregase
- Lon protease homolog, mitochondrial
- 10 kDa heat shock protein, mitochondrial
- 60 kDa heat shock protein, mitochondrial
- Stress-70 protein, mitochondrial
- ATP-dependent zinc metalloprotease YME1L1
- Elongation factor Tu, mitochondrial
- Lon protease homolog 2, peroxisomal
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
Sequence:
MWPRVLLGEARVAVDGCRALLSRLAVHFSPPWTAVSCSPLRRSLHGTATRAFPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGSPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEPELVQKETATAPTDPPAPTST
Protein: Amino acid transporter AVT3A (AtAvt3A) (Aromatic and neutral amino acid transporter-like protein 3) (Q9FKY3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Translocates preferentially neutral amino acids and to a lesser extent aromatic amino acids from the vacuole to the cytoplasm. Requires ATP for function.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:27925655}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- V-type proton ATPase subunit B3
- V-type proton ATPase subunit B2
- AT4g36960/C7A10_400 family protein)
- V-type proton ATPase subunit B1
- Asparagine synthetase 3
Sequence:
MRYDQEAGSSSHSLPSGSSSHSLPPTEDTPLLGPRTLSSQPKTFANVFIAIVGAGVLGLPYTFKKTGWLLGLLTLLFVSSLTFFCMMLLVHTRRKLESLSGFNSITSFGDLGESVCGPAGRLVVDVMLVLSQSGFCVSYLIFVATTMANLLSRGTEHILGLDAASIYLWGCFPFQLGLNSIPSLTHLAPLSIFADIVDVAATLVVMVQDVFIFLKRRPPLRVFGGVSVFFYGLGVAVYAFEGIGMVLPLELEAKYKDKFGRALGLAMGLISIMYGAFGLLGYMAYGEETKDIITTNLGTGVVSTLVQLGLAINLFFTFPLMMQPVYEVVERRLCSSRYSVWVRWATVLVVTLVALLVPNFADFLSLVGSSVCVVLGFVLPSLFHLQAFKNELSITRIVVDVLVFLIGVMIAITGTWTAVHEILTSKA
Protein: Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (EC 3.5.1.44) (Isopeptidase TGM2) (Protein-glutamine deamidase TGM2) (Protein-glutamine dopaminyltransferase TGM2) (Protein-glutamine histaminyltransferase TGM2) (Protein-glutamine noradrenalinyltransferase TGM2) (Protein-glutamine serotonyltransferase TGM2) (Tissue transglutaminase) (Transglutaminase-2) (H0VK88)
Organism: Cavia porcellus (Guinea pig)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Chromosome {ECO:0000256|ARBA:ARBA00004286}. Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus {ECO:0000256|ARBA:ARBA00004123}. Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MAEDLILERCDLQLEVNGRDHRTADLCRERLVLRRGQPFWLTLHFEGRGYEAGVDTLTFNAVTGPDPSEEAGTMARFSLSSAVEGGTWSASAVDQQDSTVSLLLSTPADAPIGLYRLSLEASTGYQGSSFVLGHFILLYNPWCPADAVYMDSDQERQEYVLTQQGFIYQGSAKFINGIPWNFGQFEDGILDICLMLLDTNPKFLKNAGQDCSRRSRPVYVGRVVSAMVNCNDDQGVLQGRWDNNYSDGVSPMSWIGSVDILRRWKDYGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNFNSAHDQNSNLLIEYFRNESGEIEGNKSEMIWNFHCWVESWMTRPDLEPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGHLNVKYDAPFVFAEVNADVVNWIRQKDGSLRKSINHLVVGLKISTKSVGRDEREDITHTYKYPEGSEEEREAFVRANHLNKLATKEEAQEETGVAMRIRVGQNMTMGSDFDIFAYITNGTAESHECQLLLCARIVSYNGVLGPVCSTNDLLNLTLDPFSENSIPLHILYEKYGDYLTESNLIKVRGLLIEPAANSYVLAERDIYLENPEIKIRVLGEPKQNRKLIAEVSLKNPLPVPLLGCIFTVEGAGLTKDQKSVEVPDPVEAGEQAKVRVDLLPTEVGLHKLVVNFECDKLKAVKGYRNVIIGPA
Protein: X antigen family member 2 (XAGE-2) (Cancer/testis antigen 12.2) (CT12.2) (G antigen family D member 3) (Q96GT9)
Organism: Homo sapiens (Human)
Interaction partners:
- X antigen family member 1
- Germ cell-less protein-like 1
Sequence:
MSWRGRSTYRPRPRRSLQPPELIGAMLEPTDEEPKEEKPPTKSRNPTPDQKREDDQGAAEIQVPDLEADLQELCQTKTGDGCEGGTDVKGKILPKAEHFKMPEAGEGKSQV