wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein YGR042W (P53227)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- ATP-dependent DNA helicase MPH1
- Inner kinetochore subunit MHF2
- Inner kinetochore subunit MHF1
Sequence:
MLSHIVEYECQYTDQLYKKRKIWHDGRLKYFQLNNRFMLYTEKDNVLLASEFKINSKELKAILNPEGFDIEEHRIFSQFLVIISNIIEEYDRDIQVAATHVRAYPSNLSVQKQRPLISDNAPSLNHISTAREVHSNIKVTTPNRKQTEDNATKGGFNISKLTLKVNKPFKKPKRILSTNVVNESNRPSIRSQKIQEVTPQLHETNTSTKVQTAGKVALNNDNIAQGNYATITEEAKVRDGSDRKKDMANLSKSGKRRVGGIRRIVHEPLGI
Protein: 72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX] (P08253)
Organism: Homo sapiens (Human)
Function: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.
Subcellular location: [Isoform 1]: Secreted, extracellular space, extracellular matrix {ECO:0000305|PubMed:2834383}. Membrane. Nucleus. Note=Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Mitochondrion.
Interaction partners:
- Metalloproteinase inhibitor 2
- Matrix metalloproteinase-14
- Metalloproteinase inhibitor 1
- Metalloproteinase inhibitor 3
- Thrombospondin-1
- Proto-oncogene tyrosine-protein kinase Src
- CD44 antigen
- Metalloproteinase inhibitor 4
- Transforming growth factor beta-1 proprotein
- Matrilysin
Sequence:
MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Protein: Protein IQ-DOMAIN 23 (AtIQD23) (Q9FIT1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity). May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:28115582}. Nucleus, nucleolus {ECO:0000269|PubMed:28115582}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:28115582}. Cell membrane {ECO:0000269|PubMed:28115582}.
Interaction partners:
- Protein IQ-DOMAIN 9
- Protein IQ-DOMAIN 33
- Protein IQ-DOMAIN 10
- Calcium-dependent protein kinase 19
- Receptor-like protein 15
- Receptor like protein 21
- Receptor-like protein 6
- Protein KINESIN LIGHT CHAIN-RELATED 1
- Calcium-dependent protein kinase 18
Sequence:
MGFFGRLFGSKKKSDKAASSRDKRRWSFTTRSSNSSKRAPAVTSASVVEQNGLDADKHAIAVAAATAAVAEAALTAAHAAAEVVRLTSGNGGRNVGGGGNSSVFQIGRSNRRWAQENIAAMKIQSAFRGYLARRALRALKALVKLQALVRGHIVRKQTADMLRRMQTLVRLQSQARARASRSSHSSASFHSSTALLFPSSSSSPRSLHTRCVSNAEVSSLDHRGGSKRLDWQAEESENGDKILEVDTWKPHYHPKPLRSERNNESPRKRQQSLLGPRSTENSPQVGSSGSRRRTPFTPTSRSEYSWGCNNYYYSGYHPNYMANTESYKAKVRSQSAPKQRVEVSNETSGYKRSVQGQYYYYTAVEEESLDVGSAGYYGGGGGDSDRLNRNQSAKSRMHSSFLV
Protein: von willebrand factor A domain protein (Q9FK36)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein CHLOROPLAST VESICULATION
- Uncharacterized protein At5g39520
- Late embryogenesis abundant protein
- At1g09500/F14J9_16
- DNA binding / transcription factor
- At5g50180
- Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial
- F18B13.24 protein
- Mitochondrial arginine transporter BAC2
- Cytochrome P450 76C2
Sequence:
MNFRGGCCIARYGGSGGGNDMSKVDRIMLRYRPIAPRPDSGGSPASPTEKNGSVITNVSSRSRRGKRKYSKENNSSSTGSVNSNGNSKRQRNDETKNGSGGGREIVTLPLLPETPEKKDSPLKAKAAPELGAAALWLSFNDGASYNRRYQTELMTETVVSSLLTVECVTERLMEGEYELGCTDEERKMNLERDTCPGFISDGLGRVIWTNGSYRELVVGKDHEQCSKMSVWLVMKEKPLVTYRTFTCRMRLQYTCRDKEVSSITSFCDVWRMSDGGFAWRLDVDAALCLGR
Protein: Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1) (Q24306)
Organism: Drosophila melanogaster (Fruit fly)
Function: Anti-apoptotic protein which functions as a caspase regulator, using its E3 ubiquitin-protein ligase activity to smother caspase activity. Binds, ubiquitinates and inactivates initiator caspase Dronc, and effector caspases Drice and Dcp-1. Acts as a Nedd8-E3 ubiquitin-protein ligase for Drice. Suppresses apoptosis by targeting the apoptosome for ubiquitination and inactivation. Plays an important role in cell motility. Overexpression suppresses rpr and hid-dependent cell death in the eye. Interaction of Diap1 with Dronc is required to suppress Dronc-mediated cell death through Diap1-mediated ubiquitination of Dronc. Acts as a positive regulator of Wnt signaling.
Interaction partners:
- Caspase Dronc
- Cell death protein Grim
- Cell death protein rpr
- Caspase drICE
- Caspase-1
- AT03047p
- Cell death protein hid
- Death-associated inhibitor of apoptosis 2
- Serine/threonine-protein kinase hippo
- Apoptosome protein Dark
Sequence:
MASVVADLPSYGPIAFDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLDWLDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPISYDICGANDSTLEMREHAYAEGVIPMSQLIQSIGMNAVNAAGSVTGTAAPQPRVTVATHASTATQATGDVQPETCRPSAASGNYFPQYPEYAIETARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTVAAKPVLAEEKEESSSIGGVAVASTQASEEEQQTSLSSEEAVSGDVAPSVAPTAATRIFNKIVEATAVATPSTNSSGSTSIPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVYFS
Protein: Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide] (E7EZ53)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1 (galr1a and galr1b) and GALR2 (galr2a and galr2b). This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P07480}.
Interaction partners:
- Galanin receptor type 1
- Galanin receptor type 1
- Galanin receptor 2b
- Galanin receptor 2a
- Galanin peptides-like precursor
- Proenkephalin a
- Somatostatin 1, tandem duplicate 1.
- Prepronociceptin a.
- Prodynorphin.
- Peptide YYb
Sequence:
MHRCVGGVCVSLIVCAFLTETLGMVIAAKEKRGWTLNSAGYLLGPHAIDSHRSLSDKHGLAGKREMPLDEDFKTGALRIADEDVVHTIIDFLSYLKLKEIGALDSLPSSLTSEEISQP
Protein: Protein TRAUCO (Protein ASH2 RELATIVE) (AtASH2) (AtASH2R) (Q9C8J7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Trithorax-group gene homolog required for early embryogenesis. Required for the expression of FLC and FLC homologs and represses flowering. Required for proper leaf growth and development. Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 'Lys-4'. Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene. Involved in the transition from transcription initiation to transcription elongation.
Subcellular location: Nucleus {ECO:0000269|PubMed:20118203, ECO:0000269|PubMed:21423667}.
Interaction partners:
- Protein RBL
- Multiple organellar RNA editing factor 1, mitochondrial
- Histone H3-lysine
- Histone H4
- Histone-lysine N-methyltransferase ATX4
- Histone-lysine N-methyltransferase ATX3
- Uncharacterized protein At5g66000
- Protein ANTHESIS POMOTING FACTOR 1
- COMPASS-like H3K4 histone methylase component WDR5A
- Histone-lysine N-methyltransferase ATX2
Sequence:
MESLQSNSKIEEAEQNPKIEEAQVSVSLPEEPTGVLLPSELVDDSAPPESSDAVEESIETASEAEVSISLLEGTTTGTALLPSEENDLAPLESSGIIEEPIDTDLEKLDVVAMDVDQPGSDLKIESDSFSEEAPTTSSSDNPKSPKLDSVANQNGSAMEEDEGDEEQDDPPHKKLKQLDCLTSVAVKEEEEPEQVLPSEAMVVEEAATLVASAAKKSKSKKKNNNVWVTKSTRKGKKKSKANTPNPAAVEDKVLITPVPRFPDKGDDTPDLEICLSKVYKAEKVEISEDRLTAGSSKGYRMVRATRGVVEGAWYFEIKVLSLGETGHTRLGWSTDKGDLQAPVGYDGNSFGFRDIDGCKIHKALRETYAEEGYKEGDVIGFYINLPDGESFAPKPPHYVFYKGQRYICAPDAKEEPPKVVPGSEISFFKNGVCQGAAFTDIVGGRYYPAASMYTLPDQSNCLVKFNFGPSFEFFPEDFGGRATPRPMWEVPYHGFNGRLETNGSEDMKS
Protein: Variant surface glycoprotein (VSG), putative (Q57UD6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MQRSQEQKRTVNGCIIAVAFIVLSITKLGKATNIEGGQNRPVFDGLCKLTKLARIDLTIPEEPNLKNQDFKDIIKLNMSLAPKAWKQVFWKTGEKNAWQDELPPKDQHGDDWEEYWLDWKEAIRSLYKADRTKAEDKITFESLPEDVKDTIRPRMINLASAAAALAKSPAAPAQLPSLKGKTLKQKLTEAVTGDGSKDVDTADYQSIYGASSGSDRQTACTTGSSGTRTNSLMGALSCVCAPETDSQADYVCTPAVAKADRWATGSPDTPSNTGKITKLCGKIPPRQLKENELRQAIEEIVALITTNSGTGYLGATKTGCTGAQGSGRCVKFTGYADNNGSIPPHTPWLTIPHSIATDLADRESRIVQAESTKAALKALAEQARKLSREGEIAKIIKGHLQTAHGQAAPGKTVNMEISDGECNKLTSNNTCKSPCKWNENTTDINKKCSLDPVKAIEQQAAQTAGTEEGAAGATTDKCGLAKTPEDFVLAKGDIPKDKKAF
Protein: AT14140p (AT18265p) (RE64054p) (Q6NR49)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHGMPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPER
Protein: Protein transport protein DSL1 (Dependent on SLY1-20 protein 1) (P53847)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for protein transport between the Golgi and the endoplasmic reticulum. May tether coatomer-coated retrograde transport vesicles to the ER membrane through interaction with coatomer as well as the SNARE complex. May contribute to the stabilization of the SNARE complex.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:11493604, ECO:0000269|PubMed:11739780}; Peripheral membrane protein {ECO:0000269|PubMed:11493604, ECO:0000269|PubMed:11739780}.
Interaction partners:
- Syntaxin UFE1
- Protein transport protein SEC39
- Protein transport protein TIP20
- Protein transport protein SEC20
- Protein transport protein USE1
- Coatomer subunit delta
- Coatomer subunit alpha
- Protein transport protein SEC22
- Protein SLY1
- Conserved oligomeric Golgi complex subunit 4
Sequence:
MESLFPNKGEIIRELLKDPLILKNDSKRSNGSELELDSSDLLQREAILANELNILDNLKTFLNLIKEVKTNLNILELENCYYSLQSLRKKMRNNAAYLKQSFNFQQSISTYVDTLHLELVSTLYKILTNGFWKITENSIQFTPTVEWGKDKVHIEYDTFMDFVAQQYFPKGSLDNQAWFILDMTSADSQEQVRAKLNTIMKEYMNLSRIVSMIKNSIFISGKEISYENEKNILVFSKSSSHGQHCVSTVLTSFEAVCDFMLDGLAFRDRKTLSYELGPLFNTEFTKFVKNNASIILESLDSPLKNLVSVINNKLTRLVAKSEVTNWTHSGKEIQDLLMNKQLYYNLLLDKVLESHISEIRSIFEDPKKSWQNLEVVELTTSNTNTMSEKIGKNDSDVQNEKELHNAVSKDDDWNWEVEDDDADAWGDEIDVNIDDEEEKTNQEKEKEPEEEENAWDEAWAIDENIDDASLENGKEHLKAHDVGSLDKDHIEVTQLPKLFLAISQNFKSSFADSHVDEQYFAYKYNLLQTSYMAMCTANFSHNWCQLYVDMRYLIERDEKLYRIKELTRNLLETKLNMKYRIVCQLIRHQLTEFRENERNPSWDATIEKLLPYILKEIVRPLQKIRGEEGSRYLLSFLNFLYNDCVTKEILKWQIISEVNSENLGELVSLLVNNTDIQLLAKEPSYKKMREKFATMGKFLPLHLKEIMEMFYNGDFYLFATDELIQWIELLFADTPLRRNAIDDIYEIRGTALDD
Protein: Protein SUPPRESSOR OF PHYTOCHROME B 5 (AtSOB5) (Q9LEZ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in cytokinin-mediated development. Promotes the expression of cytokinin synthases (e.g. IPT3 and IPT7), thus triggering the accumulation of trans-zeatin riboside, trans-zeatin riboside monophosphate and isopentenyladenine 9-glucoside.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16709198, ECO:0000269|PubMed:29467189}. Cell membrane {ECO:0000269|PubMed:16709198}; Peripheral membrane protein {ECO:0000269|PubMed:16709198}; Cytoplasmic side {ECO:0000269|PubMed:16709198}. Nucleus {ECO:0000269|PubMed:29467189}.
Interaction partners:
- Protein SOB FIVE-LIKE 4
- Protein SOB FIVE-LIKE 3
- Uncharacterized protein
- Protein SOB FIVE-LIKE 5
- Protein SOB FIVE-LIKE 2
- Protein SOB FIVE-LIKE 1
- tRNA dimethylallyltransferase 9
Sequence:
MESANIFGSDEDCRSCESGWTMYLASQSHDRDDDCYYGDDDEEEEDSDGGDSMDSDASSGPMEATSYLKLAQEIEEQNSIKKKKKKTNEEMVLVETTRVHNNINHDDDDDDDEDDGDNHDYDDGNDSYSVVHSYVGSVRQKGLV
Protein: Dynein light chain roadblock (Q7KMS3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR009998}.
Interaction partners:
- Cytoplasmic dynein 1 intermediate chain
- Dynein light chain Tctex-type
- Sperm-specific dynein intermediate chain 1, isoform A
- FI21737p1
- Sperm-specific dynein intermediate chain 2, isoform A
- GH16657p
- Dynein light intermediate chain
- Dynein heavy chain
- Dynein heavy chain at 93AB, isoform C
- Male fertility factor kl5
Sequence:
MSQEVEETLKRIQSHKGVVGTIVVNNEGIPVKSTLDNTTTVQYAGLMSQLADKARSVVRDLDPSNDMTFLRVRSKKHEIMVAPDKDFILIVIQNPTD
Protein: Chloroplast envelope quinone oxidoreductase homolog (ceQORH) (EC 1.3.1.-) (Q9SV68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: NADPH-dependent alpha,beta-unsaturated oxoene reductase reducing the double bond of medium-chain (C9) to long-chain (C18) reactive electrophile species deriving from poly-unsaturated fatty acid peroxides. The best substrates are 13-lipoxygenase-derived gamma-ketols, but is unable to reduce the double bond of short-chain alkenals and alkenones such as acrolein, crotonaldehyde, 3-buten-2-one, 4-hexen-3-one and trans-2-hexenal, or quinones such as duroquinone, decylubiquinone, coenzyme Q0, menadione, menaquinone and phylloquinone. Can use trans-2-nonenal, trans-3-decen-2-one, 4-hydroxynonenal, 12-oxo-10(E) dodecanoate (traumatin), 4-oxononenal, trans-1,3 diphenyl-2-propenone, trans-1,4-diphenyl-2-butene-1,4-dione, 9-oxo-12,13-epoxy-(10E)-octadecenoic acid (trans-EKODE-1b), 9-hydroxy-12-oxo-10(E)-octadecenoic acid, 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid and 9,13-dihydroxy-10-oxo-11-octadecenoic acid as substrates, but has no activity with 13(R,S)-hydroperoxy-9(Z),11(E)-octadecadienoic acid (13-HPOD), 9(S),12(S),13(S)-trihydroxy-10(E)-octadecenoic acid, 13-hydroxy-12-oxo-9(Z)-octadecenoic acid, 9-oxo-10(E),12(Z)-octadecadienoic acid (9-KODE), 13-oxo-9(Z),11(E)-octadecadienoic acid (13-KODE) and 12-oxo-10,15(Z)-phytodienoic acid (12-OPDA).
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000269|PubMed:17636260, ECO:0000269|PubMed:20424175, ECO:0000269|PubMed:24248378}. Note=Faces the stroma side of the membrane (PubMed:20424175). Targeting to the chloroplast inner membrane is mediated by HP30-1, HP30-2 and HP20 (PubMed:24248378). {ECO:0000269|PubMed:20424175, ECO:0000269|PubMed:24248378}.
Interaction partners:
- Short-chain dehydrogenase TIC 32, chloroplastic
- Chloroplastic import inner membrane translocase subunit HP30-2
- ADP,ATP carrier protein 1, chloroplastic
- Translocase of chloroplast 159, chloroplastic
- At1g80480
- Protein TOC75-3, chloroplastic
- Translocase of chloroplast 120, chloroplastic
- Outer envelope pore protein 24A, chloroplastic
- Chloroplastic import inner membrane translocase subunit TIM22-2
- Protein CLT3, chloroplastic
Sequence:
MAGKLMHALQYNSYGGGAAGLEHVQVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGVKNFKAGDKVVAVLSHLGGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLDGTGKKANILVTAASGGVGHYAVQLAKLANAHVTATCGARNIEFVKSLGADEVLDYKTPEGAALKSPSGKKYDAVVHCANGIPFSVFEPNLSENGKVIDITPGPNAMWTYAVKKITMSKKQLVPLLLIPKAENLEFMVNLVKEGKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIVEP
Protein: Sucrose transport protein SUC9 (AtSUC9) (Sucrose permease 9) (Sucrose-proton symporter 9) (Q9FG00)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: High-affinity sucrose transporter. Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). Can also transport a wide range of glucosides, such as helicin, salicin, arbutin, maltose, fraxin, esculin, uranose, alpha-methylglucoside, alpha-phenylglucoside and beta-phenylglucoside. Plays a role in flowering time transition delay.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17098854}; Multi-pass membrane protein {ECO:0000269|PubMed:17098854}.
Interaction partners:
- Expansin-A22
- Phosphatidylcholine:diacylglycerol cholinephosphotransferase 2
- Sugar transport protein 6
- Protein HUA2-LIKE 2
Sequence:
MSDIQAKEDAAPVDRQSSSSVVVPDEPSPLRKMISVASIAAGIQFGWALQLSLLTPYVQLLGVPHKWSSFIWLCGPISGLLVQPTVGYFSDRCKSRFGRRRPFIATGALLVALAVILIGFAADFGHTMGDKLDEAVKIRAVGFFVVGFWILDVANNTLQGPCRAFLGDLAAGDAKKTRTANAIFSFFMAVGNVLGYAAGSYTNLHKIFPFTVTKACDIYCANLKSCFIISITLLIVLTIIALWYVEDKQWSPNADSDNEKTPFFGEIFGAFKVMKRPMWMLLAVTALNWIAWFPFLLYDTDWMGREVYGGDSAGDDKMKKLYNHGIQVGSLGLMLNSIVLGVMSLVIGVISKKIGAKRLWGAVNIILAVCLAMTVLVTKKAEEHRKIAGRMALPTNAIRDGALSLFAILGIPLAITFSIPFALASIISSSSGAGQGLSLGVLNMAIVIPQMIVSFGVGPIDALFGGGNLPGFVVGAIAALISSVVALTVLP
Protein: Non-receptor protein tyrosine kinase 2-2 (S5R5H7)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MMSRSGRFKSTRTGSSTGQCEPPQGPGVHVYLFWTKGGERYLTHTEGKVTAEELSISAAQTVGITPLCHVLFSLYDPESHCWYSPNHFFNSEEQTRLTLHYRMRFYFRNWHGLSEKEPSVVRYAPRSGTEHGGSPLLEMTSLEYLFCQAKFDFVNDVTPMEDAQGKEELSRFKNESLGMAVLHLSHQALRSGCTLQEVAKSVSFLRCIPRSFAKHIARDNFLTKIRIRRVFADFVRTFQEHTVDVGRLGSQEVMYKYLSTLEHLAPRFGTETFLAAHLELRTDGGDGSGSYLNTSRAHGASDPENVGPQVMHEVMVSGTKGIQWRKMTVQKPQANSYFGNDYLGNRKSVKQSPLQQEPTSSDTWTSFCDFPEISHITITGANVSIIKQDNFSMEVQMNSSLEALSFVSLLDGYFRLTADAHHYLCHEVAPPRVVLSATNGLHGPMK
Protein: Histone acetyltransferase (HAT) (EC 2.3.1.48) (P9WKY5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Histone acetyltransferase, which by binding to the host chromatin, may manipulate the expression of host genes involved in anti-inflammatory responses to evade clearance and to survive in the intracellular milieu. Acetylates histone H3 at the 'Lys-9' and 'Lys-14' positions.
Subcellular location: Secreted {ECO:0000269|PubMed:26476134}. Host cytoplasm {ECO:0000269|PubMed:26476134}. Host nucleus {ECO:0000269|PubMed:26476134}. Note=Colocalizes with the chromatin in the nucleus of infected human macrophages. {ECO:0000269|PubMed:26476134}.
Interaction partners:
Sequence:
MSFGFPTFSQNRFTEQYSGLCPIAPGRGAGLQPCRRDCPVARWLVADHPVFGSDCRCRMMVGVNRVRIGRHELTGA
Protein: CLSTN3 protein (Q8IUW6)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAARSVALTAHVCSVYVFLQGVAWSAQLVGSWVMLHIWLYRALLETPRRVPLLPQCEQAARWLVWASMQAGKGLAQVWGVATFVQLCAHTVFLSMYLCMHICFAAISSKVRVRVNAPFCVSVPLKVHAPLSLGIKVGLQGQKHGRATGEAGMPQGEMLGKQEPQTSSSPKPTRRREVSRSELSPVIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDSALTIIVNPMEVRGLGKRGSVGSRLWSTHVLPESAVLCDGGCWGPAGG
Protein: alpha-1,2-Mannosidase (EC 3.2.1.-) (Q9VK27)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
- alpha-1,2-Mannosidase
- GH19142p
- Myosin-2 essential light chain
Sequence:
MSTTSSESFVRGQRLMLIFLVAMCIVVACVLSTETTMPTQNMSNKERAELREEARDMFYHAYNAYMQNAYPADELMPLSCKGRYRGVTPSRGDMDDILGNFSMTLVDTLDTLVLLGDFTEFDHAVKLVIRDVQFDSDIIVSVFETNIRMVGGLLSAHILAEYLQKHADTMHWYKGELLEMSRELGYRLLPAFNTSTGIPHARVNLRLGMKDPMLKKSRETCTACAGTILLEFAALSRLTGDPIFEVRAHAAMDALWKLRHRGSDLMGTVLNVHSGDWVRRDSGVGAGIDSYYEYLFKSYVLLGDDKYLARFNRHYNAVMKYVSEGPMLLDVLMHRPHAKSKNFMDSLLAFWPGLQVLSGDLKPAVQTHEMLYQVMQMHTFIPEAFTVDFQIHWGQHPLRPEFIESTYFLYRATGDHHYLQVGKKALKTLQQHAKVSCGYAAVNDVRTGKHEDRMDSFVLSETIKYLFLLFSDPQDLIINVDEFVFTTEAHLLPLSIAQLGNATFSFRQTDEHNVLDFMRTCPSSNRLFPEKVRKPLRNFITGSCPRTTAGKRLSALDFQASNADHLRAVYDMGITMVSVGDRSQGKVRLFHSFYNAKSHEEGEMGLQFMQEMLELTKMQSINQLAQLQAVAYATDENSQDWIALMAGPSHFSPELTGDQFVEGDVILAKPLRACDESLENAEEAKGKVLVAERGDCTFVSKARLAQKVGAAALIVCDNVPGSSGETQPMFAMSGDGKDDVLIPVVFMYSMEFGKLSAVMQRRKQPLRVRVMQMVEFKRWQLAKEQRQNQTASVAQKPEKEL
Protein: Small ribosomal subunit protein eS25 (40S ribosomal protein S25) (P62852)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:36517592}.
Interaction partners:
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL33
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein uL1
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL43
- Small ribosomal subunit protein uS9
Sequence:
MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA
Protein: Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.-) (Q6FVR0)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|RuleBase:RU362107}.
Interaction partners:
- Isocitrate dehydrogenase subunit 2, mitochondrial
- Isocitrate dehydrogenase subunit 1, mitochondrial
- Isocitrate dehydrogenase
- Citrate synthase
- Citrate synthase
- Citrate synthase
- Isocitrate dehydrogenase
- Isocitrate dehydrogenase
- Isocitrate lyase
- Isocitrate lyase
Sequence:
MLSARTVVRNTGVRRLATVSNLTRDSKVNQNLLEDHSFINYKQNIEYVDIVRKRLGRPLTYAEKILYGHLDDPHGQQIERGVSYLKLRPDRVACQDATAQMAILQFMSAGLPEVARPVTVHCDHLIQAQIGGEKDLKRAVDLNKEVYDFLASASAKYNIGFWKPGSGIIHQIVLENYAFPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGLPWELKAPKILGVKLTGRMNGWTSPKDIILKLAGITTVKGGTGKIVEYFGEGVDTFSATGMGTICNMGAEIGATTSVFPFNKSMIDYLKATRRDKIAEFAQLYHKDLLSADQGAEYDEVIEIDLNTLEPYVNGPFTPDLATPISKMKEVAVENNWPLEVKVGLIGSCTNSSYEDMSRSASIIKDAASHGLKAKSIFTVTPGSEQIRATIERDGQLETFKEFGGIVLANACGPCIGQWDRQDIKKGDKNTIVSSYNRNFTSRNDGNPQTHAFVASPEIVTAFAIAGDLRFNPLTDKLKDKDGNEFKLKEPFGNGLPERGYDPGENTYQAPPKDRNAVDVKVAPTSDRLQVLKPFKPWDGKDALNMPILIKSLGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAENKKANSVRNVYTGEYKGVPDTARDYRDEGIKWVVIGDENFGEGSSREHAALEPRFLGGFAIITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDKIDILGLTELAPGKNVTMRVHPKNGEAWDCELTHTFNSEQIEWFKYGSALNKIKADKA
Protein: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1) (Q9Z2Z7)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11171073}.
Interaction partners:
Sequence:
MAAPAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRSRERRRRRSPWLLLAPLLSPTVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFELLKGQIKMAKRRVVMASLYLGTGPLEQELVDCLESSLEKSLQSKFPSDLKVSILLDFTRGSRGRKNSRTMLLPLLQRFPEHVRVSLFHTPNLRGLLRLLIPERFNETIGLQHIKVYLFDNNVVLSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVDVVDGMVHPYKGDRAAYCRAANKRVMDVIHSARTRQQLLHAQTFHSDSLLSQEEAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVFLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFYGEVCGLGQQDRVQLQEYWRTGWTFHAKGLWLYLAGSSLPCLTLIGSPNFGYRSVHRDLEAQIAIVTESRALQQQLHQEQEQLYLRSSVVTSATFEQPGRQVKLWVKMVTPLIKNFF