wanglab/gogpt-training-data huggingface dataset:
Protein: Chip, isoform B (RE67266p) (Q7KVG9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Sequence-specific single-stranded DNA-binding protein, isoform D
- Beadex, isoform D
- Helix loop helix protein 3B
- Protein apterous
- LIM/homeobox protein Awh
- Insulin gene enhancer protein ISL-1
- Protein daughterless
- Protein pygopus
- Lim3, isoform G
- LD11652p
Sequence:
MQCDIQTSRRECPIEPTTGMNRRGLNAGNTMTSQANIDDGSWKAVSEGGSMLPASNSAVLNPDGSNQSGFAQGGLPYNSAGNPYPPAGQSSPAGNQSIVFQNSNQPGSNTPQYTSSPAPSGSSTPGPVGAQNIPGNYPQSATAGNFNGPVGGPFGSPSSGLGQFSRPASSGTPFNSGQAGHFSSPTVFSVGGQFNPMPPASPFGHGGNHPMMGGPQQMERIDQGFRRHNSYFSHTEHRVFELNKRLQQRNEESDNCWWDSFTTEFFEDDARLTILFCLEDGPKRYTIGRTLIPRFFRSIYEGGVSDLYFQLKHAKESFHNTSITLDCDQCTVITQHGKPFFTKVCADARLILEFMYDDYMRIKSWHMTIKGHRELIPRSVIGTSLPPDPMLLDQITKNITRAGITNSTLNYLRLCVILEPMQELMSRHKAYALSPRDCLKTTLFQKWQRMVAPPGKKDPQRPPNKRRKRKGSNSGGGNNSNTPPVTNQKRSPSGPSFSLSSQDVMVVGEPTLMGGEFGEEDERLITRLENTQYDGTNAVEHDNHTGFGHADSPISGSNPWSIDRAGAIPASPGNGAAPQNNANISDIDKKSPIVSQ
Protein: Zinc finger protein STOP1 homolog (Protein STOP1 homolog) (Q943I6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor that may be involved in aluminum tolerance.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Nitrate reductase
- Nitrate reductase
- Nitrate reductase 1
- protein-serine/threonine phosphatase
- Os04g0589400 protein
- Small ribosomal subunit protein uS2c
- Os01g0220300 protein
- Os06g0255200 protein
- Os02g0102400 protein
- Small ribosomal subunit protein mS29
Sequence:
MDSGLGRSSETSLKALPSMASNATRNTDPDQQGVRFSSMDQPPCFARPGQSFPAFPPLFGVQSSSLYLPDDIEAKIGNQFESNPSPNNPTMDWDPQAMLSNLSFLEQKIKQVKDIVQSMSNRESQVAGGSSEAQAKQQLVTADLTCIIIQLISTAGSLLPSMKNPISSNPALRHLSNTLCAPMILGTNCNLRPSANDEATIPDISKTHDYEELMNSLNTTQAESDEMMNCQNPCGGEGSEPIPMEDHDVKESDDGGERENLPPGSYVVLQLEKEEILAPHTHFCLICGKGFKRDANLRMHMRGHGDEYKTAAALAKPSKDSSLESAPVTRYSCPYVGCKRNKEHKKFQPLKTILCVKNHYKRSHCDKSYTCSRCNTKKFSVIADLKTHEKHCGRDKWLCSCGTTFSRKDKLFGHVALFQGHTPALPMDDIKVTGASEQPQGSEAMNTMVGSAGYNFPGSSSDDIPNLDMKMADDPRYFSPLSFDPCFGGLDDFTRPGFDISENPFSFLPSGSCSFGQQNGDS
Protein: Uncharacterized protein, isoform G (M9PHU7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}.
Interaction partners:
Sequence:
MDSLKLPKANSATSSASGSNSNLSGSTSASASAATSPTSSGTAVGGILSGAPKSPPGLGSSTPISVRFNANEESLDDILQSFHHSKHSPSGGASGGGDASPTSNLLGMKNNGLGLVVGNCDSLSSSPSQPQMHAGSASLFGNDEVSLRNNFMQAGGFFNRKRSGSIEGVSPTSSGPSIISTLSTASAAGGGGSSVGGAVAAGDSNSSGGTWRLIKGKVTQTIEEIKSSKLPPTAAIPIIVADPPSTGWSNDPDSDTECLTVNTSISEELPLDLEHKQNSDSDVEAELLQHDSISLGSGDVPTVAATGHSERSRLRRGLAHIRSKVKAKQQAAPAMNKKDVSPSGSTVPATSVRTGFLRRRNVVEAGSEPSTSQQAEIAIASGKVKKRGILLARKDVEIESGVEVLEDMIPSTAVHIDHSKDVANKRAEEVTDAGADADSRASLTLPVAPGFSTLASSYVEKESGVRDTRSRISFFSNLSMLSVSQWREKHQGATAFALPVLLSVLLILLMILPVPDFLRGVFATLLFFTVMDCCGGHLRALLEDFMLTTHPERVAFAIPNYKFMPICEIPAVEEHKTIKTYAGWMNEINSYDPNTFSFSLTRAVYVRLDGSILKMSGTNARIPKRRMWNEPPIDRHKIPFTDHRSYDLRDCRIELLPLGLANKRFFNRKYPIQLIIKSNRDVPDEQSSVESQSEATVKTDAKEAKAASSSGTTPPGGEEEKLVDFAGTVMQADLQQLRNTVNPDKELNDITVPCGDEVRLLLFSRCDREKEDWYRRFTNASRGLVHEQDLQVPMARFVEDSDLQAAAARQALLLVTGMGKAGVKSEDEISAGKGNDETDQQTPDGQFETITEEDLLDTPKEESFDGMIMSANVARNSPDYVRFMAVYQKACNQSTIPVTRSSVGTMRTTDRRPRKSRRAKRQEDELWKGIDQSLFLGPSGSIVWANVLLGRCLYSWLHDAMLHEKLKEVLQKKLNSIKLPSFMEEVIITNIYLGESPLLCHRVSQPMLDERGVWIDADVTYEGLAHITVTTKLNLLRIRSKTKSPMATDNVPTTSMLPEQSQDLRSLSEVNSENVIYDSDAESSGGSSTESESPPPGNAPENAAGTEFFQNSPGNARRIFKIVDRIAASNLFQYATELPYVQRAMENMNANITLRVDLKGLVARGTLNVPPPPSDRVWVSFRGPPRLWISTKPQVGDKSVDWSIVTNVIESKLCEAVNKFLVYPNMVDFSIPFLSNPNFDEDQGNAAN
Protein: Pancreas transcription factor 1 subunit alpha (Class A basic helix-loop-helix protein 29) (bHLHa29) (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA-binding subunit of transcription factor PTF1) (PTF1-p48) (Q7RTS3)
Organism: Homo sapiens (Human)
Function: Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. Cytoplasm {ECO:0000250}. Note=In chronic pancreatitis associated with pancreas cancer preferentially accumulates in the cytoplasm of acinar/ductular complexes. In the cytoplasm loses its ability to form the PTF1 complex (By similarity). {ECO:0000250}.
Interaction partners:
- Recombining binding protein suppressor of hairless-like protein
- Recombining binding protein suppressor of hairless
- Hepatocyte nuclear factor 1-beta
- Pancreas/duodenum homeobox protein 1
- Fibroblast growth factor 10
- Hepatocyte nuclear factor 1-alpha
- Homeobox protein Nkx-6.1
- Insulin
- Homeobox protein Nkx-6.2
- Forkhead box protein N4
Sequence:
MDAVLLEHFPGGLDAFPSSYFDEDDFFTDQSSRDPLEDGDELLADEQAEVEFLSHQLHEYCYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKVWTPEDPRKLNSKSSFNNIENEPPFEFVS
Protein: Phragmoplastin DRP1C (EC 3.6.5.-) (Dynamin-like protein 1C) (Dynamin-like protein 5) (Dynamin-like protein DLP1) (Dynamin-related protein 1C) (AtDRP1C) (Q8LF21)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Microtubule-associated force-producing protein that is targeted to the growing edges of the cell plate during cytokinesis. Also plays a major role in plasma membrane maintenance during pollen maturation. Has a GTPase activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14750520}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14750520, ECO:0000269|PubMed:18344418}. Cytoplasm, cell cortex {ECO:0000269|PubMed:18344418}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:18344418}. Cytoplasm, cytoskeleton, phragmoplast {ECO:0000269|PubMed:14750520}. Note=Microtubule-associated and localized in the forming cell plate during cytokinesis (PubMed:14750520). Forms dynamic foci in the cell cortex, which colocalize with part of the clathrin endocytic machinery (PubMed:18344418). {ECO:0000269|PubMed:14750520, ECO:0000269|PubMed:18344418}.
Interaction partners:
- Dynamin
- Clathrin heavy chain 1
- Mitochondrial fission 1 protein A
- AP-1 complex subunit sigma-2
- Clathrin light chain 2
- At5g57460
- Clathrin heavy chain 2
- Protein TPLATE
- Clathrin light chain 3
- Mitochondrial fission protein ELM1
Sequence:
MATMKSLIGLINKIQRACTVLGDHGGEGMSLWEALPTVAVVGGQSSGKSSVLESVVGRDFLPRGSGIVTRRPLVLQLHKTEDGTTEYAEFLHAPKKRFADFAAVRKEIEDETDRITGKSKQISNIPIQLSIYSPNVVNLTLIDLPGLTKVAVDGQPESIVQDIENMVRSYVEKPNCIILAISPANQDIATSDAIKLAREVDPTGERTFGVATKLDIMDKGTDCLDVLEGRSYRLQHPWVGIVNRSQADINKRVDMIAARRKEQEYFETSPEYGHLASRMGSEYLAKLLSQHLETVIRQKIPSIVALINKSIDEINAELDRIGRPIAVDSGAQLYTILELCRAFDRVFKEHLDGGRPGGDRIYGVFDHQLPAALKKLPFDRHLSTKNVQKVVSEADGYQPHLIAPEQGYRRLIDGSISYFKGPAEATVDAVHFVLKELVRKSISETEELKRFPTLASDIAAAANEALERFRDESRKTVLRLVDMESSYLTVEFFRKLHLEPEKEKPNPRNAPAPNADPYSDNHFRKIGSNVSAYINMVCDTLRNSLPKAVVYCQVREAKRSLLNFFYAQVGRKEKEKLGAMLDEDPQLMERRGTLAKRLELYKQARDDIDAVAWK
Protein: Olfactory receptor 7A17 (O14581)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MEPENDTGISEFVLLGLSEEPELQPFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFADICFISTTIPKMLINIQTQSRVITYAGCITQMCFFVLFGGLDSLLLAVMAYDRFVAICHPLHYTVIMNPRLCGLLVLASWMIAALNSLSQSLMVLWLSFCTDLEIPHFFCELNQVIHLACSDTFLNDMGMYFAAGLLAGGPLVGILCSYSKIVSSIRAISSAQGKYKAFSTCASHLSVVSLFCCTGLGVYLTSAATHNSHTSATASVMYTVATPMLNPFIYSLRNKDIKRALKMSFRGKQ
Protein: Caveolin-1 (Q03135)
Organism: Homo sapiens (Human)
Function: May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity). Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation.
Subcellular location: Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola {ECO:0000269|PubMed:19262564, ECO:0000269|PubMed:25588833}; Peripheral membrane protein. Membrane raft {ECO:0000269|PubMed:25893292}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:P33724}. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
Interaction partners:
- Proto-oncogene tyrosine-protein kinase Src
- Caveolae-associated protein 1
- Caveolin-2
- Nitric oxide synthase 3
- Epidermal growth factor receptor
- Estrogen receptor
- Tyrosine-protein kinase Fyn
- Basigin
- Calmodulin-like protein 3
- Calmodulin-like protein 5
Sequence:
MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
Protein: Tehao (Q58SL8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
FCLGLSPQCTCAAEGNVVRFHCPDEYAMLLEVSEPGASLYMSYYASTELQWLPRFNISSLVKIEFDAYIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETSQPENITTWHFGSVPGLKKFKFFSHVPELQESIFHGFDTLRDLHLSVNVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIHPFHERDKQLQPHFFGSMTNLEEVRLASATSSVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLDLSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLS
Protein: Coiled-coil domain-containing protein 138 (Q96M89)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEPRVVKPPGQDLVVESLKSRYGLGGSCPDEYDFSNFYQSKYKRRTLTSPGDLDIYSGDKVGSSLKYSDESKHCRTPLGSLFKHVNVNCLDDELDSFHDLKKQETEEELIENDYRVSTSKITKQSFKEIEKVALPTNTTSSRPRTECCSDAGDSPLKPVSCPKSKASDKRSLLPHQISQIYDELFQIHLKLQCETAAQQKFAEELQKRERFLLEREQLLFRHENALSKIKGVEEEVLTRFQIIKEQHDAEVEHLTEVLKEKNKETKRLRSSFDALKELNDTLKKQLNEASEENRKIDIQAKRVQARLDNLQRKYEFMTIQRLKGSSHAVHEMKSLKQEKAPVSKTYKVPLNGQVYELLTVFMDWISDHHLSKVKHEESGMDGKKPQLKFASQRNDIQEKCVKLLPLMTEQLQWMPFVNIKLHEPFVKFIYWSLRQLDAGAQHSTMTSTLRRLGEDIFKGVVTKGIQDNSPQHSVENKPKTAAFFKSSNLPLRFLSTLIVLKTVTQADYLAQAFDSLCLDLKTEEGKTLFLEYQAVPVILSHLRISSKGLLSNVIDSLLQMTVESKSLQPFLEACSNSLFFRTCSVLLRAPKLDLQILEKLSIILQKLSKIKSNKKLFELFTIHLMLQEIQRTTNPEHAFLCINLNSTLFNLGLTKCNSLVSSASP
Protein: Ubiquitin carboxyl-terminal hydrolase 50 (EC 3.4.19.12) (Ubiquitin-specific peptidase 50) (Q70EL3)
Organism: Homo sapiens (Human)
Function: Has no peptidase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20930503}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20930503}. Nucleus {ECO:0000269|PubMed:20930503}. Note=Accumulates in the nucleus following DNA injury. {ECO:0000269|PubMed:20930503}.
Interaction partners:
- Heat shock protein HSP 90-beta
- Heat shock protein HSP 90-alpha
- PAN2-PAN3 deadenylation complex catalytic subunit PAN2
- Ubiquitin carboxyl-terminal hydrolase 47
- Zinc finger protein 354A
Sequence:
MTSQPSLPADDFDIYHVLAECTDYYDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQA
Protein: Uncharacterized protein C05D10.4 (Q11181)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTARPYEPPPDYFCTHLLKNHQIEWKKPVKAKASPIHLFVFLREPMIEQRWPTTVRNSSIHPHVSSAHPSYRSHSIDAAVNRSSSACFHSPHRPSFPSRGLQKYDYPICGVSPSRHLSYNHFYNQSAAEIEEMLRTRQFPEIAGIYGNDEQPSLRRFTRYNQSINSRAVPPPAPPNPPKMEKHMSHDTSGRGSIFSKSSKKPLFFMGNWTFRDRNKSARPSISEALREERPQSMNLSDIKPATRSKSGEVLGPRNHIHIESITEFPRNIETRVPVKIERSSMVRRKPSNMGGSTEVSITSSSPSPSSSSSTSTGEFKTTITVDDDHQPTAVMRPKKESDTRGTLNNNRYSFQSCVQLRKSCPDLDSTAMSNMEQHRVSKKRTRRAKEKMSQAAWKRKTVKEWSLDDVLLWLQSAQMDDVAGLLIGYDLRGEDLLQWNDQTLAQLGVSNPEIRKKLLDDLSKIIENGPEPAQEDIRNNHRTLFDIVKQTSYDQVLAVETPLTTRDITVTHGRLGCLQITKVNGANLPLKEHDCLLEINERAGEQFKSALMLTKLISDSNGAAIRFVVLRRKTNLVVEESQQKESSSSGISSSPQTPTE
Protein: Acetyl-Coenzyme A acetyltransferase 3 (Q80X81)
Organism: Mus musculus (Mouse)
Interaction partners:
- Hydroxymethylglutaryl-CoA synthase, mitochondrial
- Hydroxymethylglutaryl-CoA synthase, cytoplasmic
- Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
- Peroxisomal bifunctional enzyme
- Trifunctional enzyme subunit alpha, mitochondrial
- Short-chain specific acyl-CoA dehydrogenase, mitochondrial
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Peroxisomal acyl-coenzyme A oxidase 1
- Succinyl-CoA:3-ketoacid coenzyme A transferase 2B, mitochondrial
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Sequence:
MNTRSDPVVIVSAARTAIGSFNGALSTVPVHEMGTTVIKEVLQRAKVAPEEVSEVIFGHVLTAGCGQNPTRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAAQSIAMGDSTIVVAGGMENMSKAPHLTHLRTGVRVGEVPLADSILCDGLTDAFHNYHMGITAENVAKKWQVSREAQDKVAVLSQNRAEHAQKAGHFDKEIVPVLVSSRKGLTEVKIDEFPRHGSNLEAMGKLKPYFLTDGTGTVTTANATGMNDGAAAVVLMKKTEAERRMLKPLARIVSWSQAGVEPSVMGVGPIPAIKQAVAKAGWSLEDVDLFEINEAYAALSVAIAKELGLNPEKVNINGGAIALGHPLGASGCRILVTLLHTLERVGGTRGVAALCIGGGMGVAMCVQRG
Protein: BBSome complex member bbs-4 (Bardet-Biedl syndrome 4 protein homolog) (Q5CZ52)
Organism: Caenorhabditis elegans
Function: Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for proper BBSome complex assembly and its ciliary localization (By similarity). May be required for microtubule anchoring at the centrosome but not for microtubule nucleation (By similarity). May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome (By similarity). Required, redundantly with bbs-5, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme. Plays a role in the removal of degraded mechanosensory receptors within the cilia.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, cilium membrane {ECO:0000250}.
Interaction partners:
- Protein pthb1 homolog
- BBSome complex member BBS1
- BBSome complex member bbs-5
- BBSome complex member bbs-7
- BBSome complex member bbs-2
- Tetratricopeptide repeat protein 8
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport protein 20 homolog
- BBSome-interacting protein 1
- Intraflagellar transport protein 74 homolog
Sequence:
MEASNQDEIIGTDVIPNEQDNPEEVVPEPTSLDVPPPPPERAPSAPKRVEILDCNSLNGLMYHYFAQGDYIECKSIIGEIQSKYLERNEAAFHVRGLIARNEGELEEAMECFHKAYELSGKNKRYFYETGRCNFLLGRHQIAVEQLTKASEVMKDNPKVWYWLARAIYHFPAEKVQGKTFNPVESARTILMKPDIAKDATLICFLGRLCEELGDTSGAIAAYKSSLKLQPDNTEVMNLLGLIYLRTGQVQEGFVQLGNCLAYDPANSQAILTIGSIMQNHSDHDVALNKYRVAADVSDYNGCLWNNIGIGLLARNKPAASHSALKKAAFINPLNYKISYNLGVLHDIMNLHCSALHYIKLCTELYPQNAKAVGAMAVILSHMNDDKNARLAYKKSIELKKNPSTILNYAIFEYRMKDVTAASNALKLYKDLQASGVKCSANNKETANLLESVLKQPDQSAEQ
Protein: LD20239p (RE02054p) (Reduction in Cnn dots 6, isoform A) (Reduction in Cnn dots 6, isoform B) (Q7JR73)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNYQKASEKQSSSSLKKRPPGNGNSIQNFWNDRIMERFIKANLFIICCVVAVLLLIVYLGAFSCEVSWILEAHGELPFAAYTLCSLYFVMFVATTILIHGLVSGLCWPLFAWSGIIGLLSIPELVFVMIMTTQHWGLQSVHGLTELTSYLIRLIINCFALICVIPTGIRWRRETQVLSQLQGLATRLSLQTPAPSVPITKADSRRSSQRLSGFENAGYQLCDETASKLPLGPGMGLGMNNQCGGSQAFGSQNEFNASMFAPALAQQFNNATLMQRGGTGGAGGGHRAQSLMDLRCTLPGMYNPRHVLDTEDKNAKYFNITIDDLKNNLHDSHRPSPPSLIGSTSNDPIYCSIEPKQLTPPPAQQRSHHRPRGTHKQPPPGKLSRNCVSLENLDGISKVQNDLTAYGNNLLQNYTQQQQYYLAMLLHQQQQQQLHHQQAGGIYRRPSNCSSTGGFAGTVLAQPMQRRGSTHSQQMQYYGGFGYANYTNPYITANSKLSLGNESDDYRKYRDVAL
Protein: 26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5) (Q8BG32)
Organism: Mus musculus (Mouse)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 8
- Proteasome subunit alpha type-2
- 26S proteasome non-ATPase regulatory subunit 1
- 26S proteasome regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome regulatory subunit 4
- 26S proteasome non-ATPase regulatory subunit 2
- 26S proteasome regulatory subunit 6A
- 26S proteasome non-ATPase regulatory subunit 6
Sequence:
MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYSKAKKLT
Protein: Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2) (Q9BQI0)
Organism: Homo sapiens (Human)
Function: Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18699778}. Cell projection, ruffle membrane {ECO:0000269|PubMed:18699778}; Peripheral membrane protein {ECO:0000269|PubMed:18699778}; Cytoplasmic side {ECO:0000269|PubMed:18699778}. Note=Colocalizes with F-actin. Partially relocates to membrane ruffles in response to invading bacteria.
Interaction partners:
Sequence:
MSGELSNRFQGGKAFGLLKARQERRLAEINREFLCDQKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEGKANESSPKPVGPPPERDIASLP
Protein: Transcription factor 7 (B7WNT5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFPTELLTSPAEPAPTSPGLSTALSLPTPGPPQAPRSTLQSTQVQQQESQRQVA
Protein: RCC1 repeat-containing protein C10F6.04 (O42645)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Diphthamide biosynthesis protein 3
- Probable tRNA
- Cytoplasmic tRNA 2-thiolation protein 2
- GTP-binding protein ypt1
- Inositol diphosphatase siw14
- tRNA modification GTPase mss1
- Probable 3-mercaptopyruvate sulfurtransferase
- Probable tRNA-splicing endonuclease subunit sen54
Sequence:
MLLSLGSNGNFQLGLNNDEDVYSPQIVPFDRAIEKISCGGNHTLLLDEDSQLWACGDNRKGQCGYEVKEPLYNPLSPDYLRIFTRVSHERWVFLTCGWEFSVIVHADRRRVCSCGEGLSGELGQGNRSNSQGLREIDIPYLDDKEFIIDISAGLRHWICVTNEGNLYGCGDGRKGQLGPVVMKTVNKVSFLGRIEHAQAVVCGVQFSAVLQETGHVIVLGGEKWNVAAECDAWQANNSELSSSICSISANWSTLSLLSTEGCVYAFGRCDRAQKAHTKASDIVQIASGTEHNILRTKKGSVLIYGWNEHGNASNDDKRDVYDAKTLQLPGWAYIVAAGYATSWIVIEENHK
Protein: E2F transcription factor 7 (F8VXV5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEVNCLTLKDLISPRQPRLDFAVEDGENAQKENIFVDRSRMAPKTPIKNEPIDLSKQKKFTPERNPITPVKFVDRQQAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKD
Protein: Retinol dehydrogenase type 1 (Q8VIJ7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MWLYLVALVGLWTLLRFFRERQVVSHLQVKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGISTPSGPNEWMKKQDFARVLDVNLLGMIEVTLSMLPLVRKARGRVVNVSSVMGRMSFFGGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGGFKTCVTSSDRLSSNTKMIWDKASSEVKEIYGEKFLLFYLKNLNELDKRCNKDLSVVTDCMEHALTARHPRTRYSAGWDAKFLFLPLSYLPTFLVDALLYWTSMKPEKAL
Protein: Rabaptin-5 (B2BWH4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Early endosome {ECO:0000256|ARBA:ARBA00004412}.
Interaction partners:
Sequence:
MAEQASGSTRPPQHDGVEQEQDRTDFLKLKQQLEMEFNQKRAKFKELYLSKEEELKRQTAILEKAQAEMCSVQEELADAKAEMETIKAVATLSESTKQEAIDQVKQLWQEEVASLQAIMKDAEREFKLQFQQKLEQERAQWTQYRDGVEREIAELRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMESEIAALKAKLSSSEDRVKELEAAKVKELNHVLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVVHLLELERQQHNQLKHTWQRANDQFLESQRLLMQDMQRIESVLSSEQLRQVEEIKKRDQEEDEQERLSQAKEASEDDGTGHAEAVEDSLLGLSIEESHLSHSIHSSLHSLDADTPGRPDSSDPYKDGLRRVQSTDSLGSSGGSLQPHGLGGHNNKAKSASQLDESDFGPLVGADCGGFDSMDTSSISSLQPGHFLLTKDQEKAIKAMTPEQEETASLLSSISHTADTAYLPPSGYRLVSESEWNLLQQELKNAGRKLGRRCDMCSNYEKQLQVIQGQEAETRDQVKKLQAILRQANDQLERTMNEKQELEDSVKQANEDTTAKISELKQKVQESESPFSALQQAFSQAKRNTQEQMAVLLQSREQVSEELNRLQRDNESLQGKHRLHMTLQQQEDFHMPTTVQELQKLVLQYREDIVSARTAAEHLEEKLKAEILFLKEQIQAEQCLKENLEDTLQLEIEGCKEEIASFSSLKTELERVKSEKEQLESSLAEKSQMLESVQRLKSSLEEQLKDTLGSKSALETQVFEEKDKSQRLQAELDVSEQVQRDFVKLSQTLQVQLERIRQAESLDRIRAILNDTNLTDISQLPET