wanglab/gogpt-training-data huggingface dataset:
Protein: Enoyl-CoA hydratase/Enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase, putative (EC 1.1.1.35) (Q586V7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
Interaction partners:
- Hydroxymethylglutaryl-CoA synthase
- propanoyl-CoA C-acyltransferase
- Probable enoyl-CoA hydratase, mitochondrial
- Succinyl-CoA:3-ketoacid-coenzyme A transferase
- Acetyl-coenzyme A synthetase
- Aldehyde dehydrogenase
- 3-hydroxyisobutyryl-CoA hydrolase
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- hydroxymethylglutaryl-CoA lyase
- HotDog ACOT-type domain-containing protein
Sequence:
MRRLETISSHVGFRRFCHLQRRGDAVVLILHHELLNALTVDMRAALLHFFNEADNDSSVKCIIIAGEGGAFSCGIDINDFAASLVDTTKENGVRIPSLPSLTTRIEQSDKVVIAATSGITYSGGLELALAAHYRVASPTSVFCMPEVKLGIVPCGGATQRLPRLIGVRAALDIISTGRKVSAKEALRLGLIDHLTSSPHEERRDQDVNGVSAQGPFCCTDPNGNLESAIEAALRLSARWTKPRRISCDATKLGIMLYNSILFRRVGSEITKKAPKEVSAPLQCLQAIRAATNSASFKEGLAEETRIFKQTLHSPEAHAMQHLLRSSYTVLSDTLPTLPVRAGTGLQQQRLRKLAVVGCGVVGIGIVIMALRAGSQVVLLGEDDNECEYALHVIKSELPNDALGYNISADCVNMYLNNLKVLPYHGDLQTVLQDVDVMAECIVGDLDTKRQVFTMLTDLCPPHCVLATCCSSLELREFVKVSRRPEKVVGMYFAPPVHNVPFLEVTRGYRTDHTTLQRAIHVGRLFHKATILTRDVGFSIISRIFFAILYQALSMLEQGAFPVDIDRAMRHFGFRLGIFAMEDLAGLQVVSQILNSLRVREGCSGVRSPCPPTDVFTIHRRLVEMGHFGQKTGRGWYTYEEGDLFSSLAAWRQRLIGSASNSTKNTYGVWSKGGASLMRRPYQDRDVELLILDVCREKKIMRRDISRKEMIERILFAAVNEAAMLLREEAVSSSSAIDIATTFGHGFPAWRGGLCYYADKFGLPNVVHRMRIYNKTFGDALFPLPCEELRQMASSQQTFRSTWP
Protein: Cadherin domain-containing protein (Q3TU38)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MKDNYCLQAALVCLLHSDIDAGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNKPLGPPSEFIDKDQDINDNPPEFLREIYHTNVPERSNVGRNISYQVTASDADNPTYGKSAKLVYSILEGQPCFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTRVTITLTDVNDNSAKFPKSKESKLVFDNDHCSARASSFLSLLIYPAFKRKSLEIQESFS
Protein: Ccdc85 (RE60986p) (Q9VQK1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell junction, adherens junction {ECO:0000256|ARBA:ARBA00004536}.
Interaction partners:
- FHIP family protein CG3558
- Uncharacterized protein
Sequence:
MSGNQQQQQQQQKSLTNNAAAAATNEATTLGHNLIKINSVDKIVGKSQAATQAINKLQQQQQQQHQQQQIHQRRSLLPATGGATNPHQPHSSQQQSGTPTPTAQSAAQKQQQQQQQSHQLQTVATIHQPHSTQQQALTSRLPIQQQSTKELPNLAGQQRRSFHYQLQNQQQSLRSPQLKAPAPAHSIPPRYQPPPQPATGILKPHLPLKYPPDIPQLSSIYIPDSIKQQQQQQQQQQSRYLPAHQPGAKDMLKFVRKPDQEHPSPNASVTSSGTGIPTANGGGRLTAEQNRQLQSLVNELRALKEQNQRLLDDNQELRDLCCFLDDDRQKGRKLAREWQRFGRYTASVMRQEVAAYQNKLRQLDDKQQELITDNLELKELCLYLDEERAHVAANALCAGCGAATRNALRDDGDGSSSSTNADETITALRNYAEQRQLPQDLRHAHTLNDQTLQYVRSLERRIQQLEEERTTPTAHLQQPTTPTPQATPTPTVTSAATPAKSAASPHQQQQQQQQHQQQQQDIVAAAAAAAAAIQLPEPIAGRPEAVVRALQVLEVREQLERDRLGNLAGSALDQMDDGEKALVREMCNVVWRKLEGSPHGPAALEPL
Protein: Probable alpha-1,3-mannosyltransferase MNT4 (EC 2.4.1.-) (P53745)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Mannosyltransferase KTR6
- Alpha-1,3-mannosyltransferase MNN1
- Uncharacterized membrane protein YNR062C
- Putative uncharacterized protein YCL021W
Sequence:
MVLRIRRIKKLAPLIFTSLLSLIVLFRVYRQYPFSDHFETRREDDRSGNVHCFSRLRQIEEYEKPELTSKFYEPNRWKSFISYVTRSRKDVKTVSRSLSNLDLYQKCSKEIRADQDISLLHSIETKLFPYINFTALNSEQSHNFWPVHTRFDGTKYRGQVLQFSSENNSFIGTSPIEFKASEPFWENWLNSALQRNSKGVVMSVSEYLVADTIRLIRVLRLLNNSLPIEIVHKSDLHESSQQLLIAAARESGSLNYPPQELWFLDVKDMLNDEYLARFKRFSNKWLAITFCSFQIPIFLDSDTVPFVPLDTLYEIDGFKRTGTLFFKDRSFPTSKLSPLQVKVLKQIINNSLDVSSDSEQGFEILKHNLNDEMAIDAIEALIFKKQKHYMDSGLVIFDKQKHFFCLPIAIMLQFSPIQEFFHGDKEWFWLSLFISKKEFTFYPIEASNVGRLEKPETLESSTICSTQLSHTDVYGNLLWLNGGLSVCKKNCWNYDFTKRKEIAAKYKSVDELRNYYQSPVKLEAVIIPDVSKSPWSQQSECVMYSYCTHYRKGQYGKLIEFTDSQKKYYEKVVELWNKVV
Protein: ATP binding protein-like protein (Q381H0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTNPAEQALLRIAETIERAVDDEMERVDNMDDEELLDIRRKRLKALKEMEARREAWIRKGHGRLHEVSDPKEFFQFVQESERVVVHFMRRSTSRCSILERHLQIIAPQHFETRFCYVDVERIPSLAERFNVLMLPTLMLVENKNTFHSIIGFDEFGGTDDFASETVIKVLASYGMLNEQGMFAADQGND
Protein: Dynein light chain Tctex-type 5 (Tctex1 domain-containing protein 1) (Q66IC8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Dynein light chain Tctex-type 1
- Dynein light chain roadblock-type 2.
- Si:dkey-148f10.4.
- Dynein light chain Tctex-type 1
- Ssu-2 homolog, tandem duplicate 1.
- Dynein axonemal intermediate chain 4
- Cytoplasmic dynein 1 intermediate chain 1
- Dynein light chain roadblock
- Dynein light chain
- Protein SSUH2 homolog
Sequence:
MSDLAKEKARLLKKRGSLSSLGSHEVRAIGKTKDSISTLSYMEEHGHHDDIQRPTVQMENTYRITPSRRFPVLTVKDLLKDVLTSYLQEEKYETELCRQMTKTITEVVKARVKDLMIPRYKIIVVISIGQIKDQNIRMGSRCLWDDNHDNFSSHIFKNNSLFAAATVFGVYFE
Protein: Arsenate reductase 2.1 (OsACR2.1) (EC 1.20.4.1) (Dual specificity phosphatase CDC25.1) (Sulfurtransferase 20) (OsStr20) (Q336V5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Possesses arsenate reductase activity in vitro. Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. May play a role in arsenic retention in roots.
Interaction partners:
- Os11g0586100 protein
- Wee1-like protein kinase
- Cyclin-dependent kinase A-1
- Cyclin-dependent kinase A-2
- [RNA-polymerase]-subunit kinase
- protein-serine/threonine phosphatase
- Os05g0483900 protein
- Cyclin-dependent kinase B2-1
- Os05g0483801 protein
- Os05g0484000 protein
Sequence:
MCRFLISTPFSRRRGERKAEAGRMARSVSYVSAAKLLAMARSNPRVAIIDVRDEERSYQAHIGGSHHFSSRSFAARLPELARATGDKDTVVFHCALSKVRGPSCAKMFSDYLSETKEESGTKNIMVLERGFNGWELSGQPVCRCTDAPCKGTCSPEEPEL
Protein: Myocardin related transcription factor A (A0A8I5ZKI6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
LRTLQSPKRSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEALIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLESRASDLLPSATSISPTQVLSQLPMAPDPGETLFLAEQPPLPPPPLLPPSLTSGSIVPTAKPAPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPPKPSGETPGSSAPTPSRSLSTSSSSSSGTPGPGGLARQNSTALAGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTSVLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNGMVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDAFGEMVTSPLTQLTLQASPLQIVKEEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASSPVKRESSFSSCQLSCQPQGAARAFGPGLVVPTTNHGDAQAPAPESPPVVVKQEAGPPEPDLAPASQLLLGSQGTSFLKKVSPPTLVTDSTGTHLILTVTNKSADGPGLPTGSPQQPLSQPGSPAPGPPAQMDLEHPPQPSFATPTSLLKKEPPGYEETVTQQPKQQENGSSSQHMDDLFDILIQSGEISADFKEPPSLPGKEKSPPAEAYGPPLTPQPSPLSELPQAAPPPGSPTLPGRLEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSPMDTSELHFAPEPSSGMGLDLAVGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSMDFLDGHDLQLHWDSCL
Protein: Cell division protein ZapE (P71967)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MTLIAARRYSATMHGSASEACGSVDHLVDRHPTVSPVRLIAQLRPPPTFAEVSFATYRPDPVEPTQAAAVVACQDFCRQAVERRAGRKKWFGKRDVLPGVGLYLDGGFGVGKTHLLASAYYQLPGTGPDAPTCPKAFATFGELTQLAGVFGFADCIDLLANYTALCIDEFELDDPGNTTLISRLLSALVERGVSVAATSNTLPEQLGEGRFAAQDFLREINTLASIFTTVRIEGPDYRHRDLPPAPAPLSDEEVAARAARVEGATLDDFDALCAHLATMHPSRYLTLIEGVTAVFLTGVHGIDDQNVALRLVALVDRLYDAGIPVVASGAKLDTIFSEEMLAGGYRKKYLRATSRLLALTAGVIQAREP
Protein: Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) (P30549)
Organism: Mus musculus (Mouse)
Function: This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Protachykinin-1
- Tachykinin-3
- Tachykinin-4
Sequence:
MGAHASVTDTNILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGSTFCYFQNLFPVTAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAVIWLVALALASPQCFYSTITVDQGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLVVMFAAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHLYFILGTFQEDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWGTPTEEDRLELTHTPSISRRVNRCHTKETLFMTGDMTHSEATNGQVGGPQDGEPAGP
Protein: Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1) (Q90966)
Organism: Gallus gallus (Chicken)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity). Required for hindbrain patterning and appears to be required for skin development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- Retinoic acid receptor RXR
- Arginine--tRNA ligase, cytoplasmic
- Cytochrome P450 26A1
- Cellular retinoic acid-binding protein 2
- Cytochrome P450 26B1
- Retinal dehydrogenase 2
- Aldehyde dehydrogenase 1A1
Sequence:
MASNSSSCPTPGGGHLNGYPVTPYAFFFPHMLGGLSPPSSLPGIQHQLPVSGYSTPSPATVETQSTSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKDVPKTECSESYIVTPEVEELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDKVDKLQEPLLEALKIYVRKRRPNKPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGMDTLGGQPGGPRTGGLGPPPGSCSPSLSPSSTRSSPATHSP
Protein: FI19917p1 (Q9VTL0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RH57257p)
- Sorbitol dehydrogenase
- Sorbitol dehydrogenase
- Dihydropteridine reductase
- Dihydrofolate reductase
- Sepiapterin reductase
- RE21057p
- Pyrimidodiazepine synthase
- Beta galactosidase, isoform A
- Glutathione S transferase O3
Sequence:
MSTPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPFEPKAKVDN
Protein: AP complex subunit sigma (Q9VCF4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004156}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
Sequence:
MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLLQEDETPQSFFDDHGLG
Protein: Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT) (P28337)
Organism: Gallus gallus (Chicken)
Function: The glycine cleavage system catalyzes the degradation of glycine.
Subcellular location: Mitochondrion {ECO:0000305|PubMed:1526969}.
Interaction partners:
Sequence:
MLRAGCRAALARRHLSSAPEGLKQTPLDALHRARGGRMVPFAGWSLPVQYGRGHLESHLHTRRHCSLFDVSHMLQTRVYGRDRVRFLESLVVGDIAELRPGQGTLTLLTNERGDIVDDLIVTNTAEDHLYVVSNAGCADKDRAVMEGRAAELRAAGGDVHLEVSGQRAAGVQGPSMAQVLQAGLPDDLTKLTFMTSTATTVFGVPGCRVTRCGYTGEDGVEISVPAGRAVELAERLLGCPEVWPAGLAARDSLRLEAGLCLYGNDIDESTTPVEAGLLWTLGKRRRTAMDFPGAAIIMEQVKEKPKRKRVGLTSVGPPLRPPAAILGPEGTPVGTVTSGCPSPSLGKNIAMGYVQAAHSRPGTTLTVEVRKKQHPALVTKMPFVPTHYYMAK
Protein: Elongation factor 2 (EF-2) (O14460)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS3
- Elongation factor 1-gamma
- Large ribosomal subunit protein eL8
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL18A
- Small ribosomal subunit protein uS10
Sequence:
MVAFTPEEVRNLMGKPSNVRNMSVIAHVDHGKSTLTDSLVQKAGIISAAKAGDARFMDTRADEQERGVTIKSTAISLFAEMTDDDMKDMKEPADGTDFLVNLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIRPVVVVNKVDRALLELQISQEELYQNFARVVESVNVVISTYYDKVLGDCQVFPDKGTVAFASGLHGWAFTVRQFANRYAKKFGIDRNKMMQRLWGENYFNPKTKKWSKSATDANGNSNQRAFNMFILDPIYRIFDAVMNSRKDEVFTLLSKLEVTIKPDEKELEGKALLKVVMRKFLPAADALMEMIVLHLPSPKTAQQYRAETLYEGPMDDECAVGIRNCDANAPLMIYVSKMVPTSDRGRFYAFGRVFSGTVRSGLKVRIQGPNYVPGKKDDLFIKAIQRTVLMMGSRIEPIEDCPAGNIIGLVGVDQFLVKSGTLTTSEVAHNMKVMKFSVSPVVQVAVEVKNGNDLPKLVEGLKRLSKSDPCVLCTTSESGEHIVAGAGELHLEICLKDLQEDHAGIPLKISPPVVSYRESVSEPSSMTALSKSPNKHNRIFMTAEPMSEELSVAIETGHVNPRDDFKVRARIMADEFGWDVTDARKIWCFGPDTTGANVVVDQTKAVAYLNEIKDSVVAAFAWASKEGPMFEENLRSCRFNILDVVLHADAIHRGGGQIIPTARRVVYASTLLASPIIQEPVFLVEIQVSENAMGGIYSVLNKKRGHVFSEEQRVGTPLYNIKAYLPVNESFGFTGELRQATAGQAFPQLVFDHWSPMSGDPLDPTSKPGQIVCEARKRKGLKENVPDYTEYYDRL
Protein: Galectin-12 (Gal-12) (Galectin-related inhibitor of proliferation) (Q96DT0)
Organism: Homo sapiens (Human)
Function: Binds lactose. May participate in the apoptosis of adipocytes.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MSQPSGGRAPGTRIYSWSCPTVMSPGEKLDPIPDSFILQPPVFHPVVPYVTTIFGGLHAGKMVMLQGVVPLDAHRFQVDFQCGCSLCPRPDIAFHFNPRFHTTKPHVICNTLHGGRWQREARWPHLALRRGSSFLILFLFGNEEVKVSVNGQHFLHFRYRLPLSHVDTLGIFGDILVEAVGFLNINPFVEGSREYPAGHPFLLMSPRLEVPCSHALPQGLSPGQVIIVRGLVLQEPKHFTVSLRDQAAHAPVTLRASFADRTLAWISRWGQKKLISAPFLFYPQRFFEVLLLFQEGGLKLALNGQGLGATSMNQQALEQLRELRISGSVQLYCVHS
Protein: protein-tyrosine-phosphatase (EC 3.1.3.48) (A0A286YBL8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Protein tyrosine phosphatase, non-receptor type 23, b
Sequence:
MPLPFGLKLKRTRRYTVSSKSCLVTRIQLLNGEYVEFTLSVESTGQECLEAVAQRLELREITYFSLWYYNKQNQQRWIDLEKPLKKQLDKYGLEPTVYFGVVFYVCTVTQLQQEITRYQYYLQLKKDVLEGKIPCSIEQAIHLASLAVQADLGDFNRYDSQEFLQKIVLFPMPWIQDERVVEEATQKVTMLYQNYRGLSAPEAELLYMQEVEKIEGYGEESIQAKDSQATDVIIGSCLDGIFVKHKNGKAPLIFRWNDINNMTHNKSFFALELANKEDTIQFQTEDMETSKYVCRMWLARHKFYKINNSSLEPSCDPNSEGPQRSILSLSFPRFPALSRLSVPADKGQTQPAPVNPVRRRSSTRMSLPKPQPYMMPPQMHFNGHYNEPYTSSQDNLYINNQNGFYYHSQTSLDRSPHEYNGRIRNGSVYSAQSTSSLNNPQHYLQPSPMSSNPSITGSDLMRPDYVPSHRHSALIPPSYRATPDYETVMRQKNMIPAAERQSHSMRNLNIGNSYAYSRPDPLVYSQPEIREHGAGQYPFHLNYSFHSPSPYPYPTERRPVVGAVSVPELTNVQLQQAQEYPPPNIIRNQVYWPPPPYPYPHPRPANSTPDLSRHLYVSSSNPDLITRRVHHSVQTFQEDSLPVAHSLQEVSEPLVTARRPHMHKRNSIEIAGLAYGLENMRLKERKVSASAADTPPPVAAAVPHAASGSDINVVLEVSKPEDVGIKEDVFYGHKKSLSDATMLVHSSGEEEEFEDDSGRHTPQSQDAVSGPEHPMTSLGRSLGDPPAYPFSHSMETVLTSPPAYQAHSIMQKAEDVGPLPPLREPGLMMPSVSEGDLSGRLRKNRDISKRPVSDVPPGRRNIDGLPPAGMKKGRSEVKKVGPLKLAALNGLTLSRIPLPDDGKDDPESASNDERCKFLEQRLDQGMVFTEYEQVPKKRPNSEYSIAQMPENNDRNRFQDVLPYDDTRVELVPTKENNTGYINASHIRVTVRGKEWSYIASQGPLSSTCQDFWQMVWEQGVSIIAMVTAEEEGGREKSFRYWPRLGSRHNTVTYGRFKITTRFRTDSGCYATTGLKIKHLLTGQERTVWHLQYTDWPDHGCPEDFKGFLSYLEEIQSVRRHTNSSSDPKNTNLPVLVHCSAGVGRTGVVILSEIMIACLEHNEMLDVPTVLNLLRQQRMMMVQTLSQYTFIYKVLIQFLKNSRLI
Protein: Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Q7ZTY4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q16576}.
Interaction partners:
- Polycomb protein suz12-A
- Polycomb protein suz12-B
- Protein lin-9 homolog
- Metastasis-associated 1
- Lin-37 DREAM MuvB core complex component.
- Polycomb protein eed
- Metastasis-associated 1 family, member 2.
- Zinc finger protein AEBP2
- Histone-lysine N-methyltransferase EZH2
- Protein lin-52 homolog
Sequence:
MADKEVYDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTVQWLPDVNRPEGKDYVVHRLVLGTHTSDEQNHLVIASAQIPNDDAQFDASHYDSEKGAEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPTSDVLAFDYTKHPSKPDPSGDCSPDLRLRGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISGAPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPASELEGQAS
Protein: Bruno (O02374)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFTSRASFLANRRMIFDFSEKNNDIYLDAFGMSDKSSSATNSLPNSPIHSNNNNPSLLNNNNNNSNGTSSNNSLNVGNNNSNPSLGGTNSNALVSVGSNGIMSAAGLVNNNNNPCSANRNVVAMVDDDACFRLDTDATVTYGEKEPDPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCFVTFYTRRAALKAQDALHNVKTLNGMYHPIQMKPADSENRNERKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNGQSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQIQANLWNLASNINIPLGQTATSVTTPILPNPPQQPSPVLGADAITPASIQLLQQLQAVGLQHQLLQALTGLGAQQSSSATDTSAVAAAGLLTPMTVQNLAAIAAMTQPSLSNAAAAAARATSPGSAQLTNTAALLWSDPNPMASAYMSTAAGLPQFGSASALSTSPLASVALSAAAAAAAGKQIEGPEGCNLFIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKKPKDSKPY
Protein: Pannexin (B1P2E8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU010713}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU010713}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MQNILEQNLDMATALLAGEKLKELIMPGSTQDGKGGVLAGLMVQLXLELPFDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQALYARGYCWTELRDAVPGVDPELRPSLFEHKFLPYALLAFAGIMYIPALGWEFMASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITERERREIIENAEKEKSPEQNLFEKYLERRGQSNFLAKLYLARHLAIICLSSIPITYLSAYYARQRQNEFTCALGGPPDTSSIPELRLNVNCKLPAVQLQRIMAAVDIALLCTMNLIILLNLLHLFVVRKSNFVFDKLHKVGIKTRRRWQKSPFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGIQTIDPSMDPSVLGVGELGGEPSVIKRPRKKMKWIPTSNPLPQSFKEPLTLTRLENSIKAEKPKPVRRKNVADSIIAPLLDSKSTQYPPTSKDTYNTQKKHSLNLSLDVHPYMLTIQKAETVNPEPPPVEHSISSVYIEGPHTVVHVSSTLTEKKESPPLSTTTAFSTATLPTNSYLNGGTASMPPPLDSPKVIGPLNQETEPESQPVPFSRNPSLPLPSIHHTLYEKDEDDQNRRLARPGELIAAGEC
Protein: GON domain-containing protein (Q8CDB8)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MRYVSCRDEDGSVADESACATLPKPVAKEECSVTPCGQWKALDWSSCSVTCGQGKATRQVVCVNYSDHVIDRSECDPDYIPETDQDCSMSPCPQWTGLAHPFQNEDFRPRSDSPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTANDCVERIKPDEQRACESGPCPQWAYGSWGECTKLCGGGMRTRLVVCQRANGDRFPDLSCEVLDKPTDREQCNTHACPQDAAWSTGPWSSCSVSCGRGHKHRNVYCLAKDGSHLESDNCKHLPKPHGHRRCRGGRCPRWKAGAWSQCSVSCGQGVQQRHVGCQIGTHKAARESECSSYSRPESERVCQASPCPLYTWRAEQWQQCTKTCGEGSRYRQVVCVAEDQSEVHSTHCDSDQRPPDRESCSLQPCEYVWITGEWSECSVTCGKGYRQRLVSCSEIYTGKENYEYSYQTTVNCPGAQPPSVHPCYLRDCPVSATWRVGNWGSCSVSCGIGVMHRSVQCLTNEDQPSHLCPTDTKPEERKACRNVYNCELPQNCKEVKKLNSASVDGEYFLAVRGKPLKVFCAGMNSDYPKEYVTLAHGDSENFSEVYGHRLHNPTECPYNGSRRDDCHCRKDYTAAGFSSFQKIRLDLTSMQIITTDLEFARTSEGHPVPFATAGDCYSAAKCPQVCPQAIPLPRNPPLTLLPRPLCPLFLELEQLITGQFI
Protein: Phytochrome-associated serine/threonine-protein phosphatase (EC 3.1.3.16) (PsFyPP) (Q8LSN3)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: Catalytic subunit of protein phosphatase 6 (PP6) (Probable). Dephosphorylates phosphorylated phytochromes, with a preference toward Pfr forms. Plays a major role in the photoperiodic control of flowering time in long days by modulating phytochrome signals in flowering time control.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12468726}.
Interaction partners:
Sequence:
MDLDQWISKVKDGQHLLEDELQLLCEYVKEILIEESNVQPVNSPVTVCGDIHGQFHDLMKLFQTGGHVPETNYIFMGDFVDRGYNSLEVFTILLLLKARYPANITLLRGNHESRQLTQVYGFYDECQRKYGNANAWRYCTDVFDYLTLSAIIDGTVLCVHGGLSPDIRTIDQIRVIERNCEIPHEGPFCDLMWSDPEDIETWAVSPRGAGWLFGSRVTSEFNHINNLDLVCRAHQLVQEGLKYMFQDKGLVTVWSAPNYCYRCGNVASILSFNENMEREVKFFTETEENNQMRGPRTGVPYFL
Protein: RNA-binding (RRM/RBD/RNP motifs) family protein (F4JYK6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- RNA binding
- Cleavage stimulating factor 64
Sequence:
MEMESCKLFIGGISWETSEDRLRDYFHSFGEVLEAVIMKDRATGRARGFGFVVFADPNVAERVVLLKHIIDGKILVDSIVYNQLCRSDKCISLSEVVEAKKAVPRDDHVVFNKSNSSLQGSPGPSNSKKIFVGGLASSVTEAEFKKYFAQFGMITDVVVMYDHRTQRPRGFGFISYDSEEAVDKVLQKTFHELNGKMVEVKLAVPKDMALNTMRNQMNVNSFGTSRISSLLNEYTQGFSPSPISGYGVKPEVRYSPAVGNRGGFSPFGHGYGIELNFEPNQTQNYGSGSSGGFGRPFSPGYAASLGRFGSQMESGGASVGNGSVLNAAPKNHLWGNGGLGYMSNSPISRSSFSGNSGMSSLGSIGDNWGTVARARSSYHGERGGVGLEAMRGVHVGGYSSGSSILEADSLYSDSMWLSLPAKAEEGLGMGPLDFMSRGPAGYINRQPNGGIAA
Protein: cAMP-dependent protein kinase type I-beta regulatory subunit (P31321)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:23115245}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit gamma
- cAMP-dependent protein kinase type I-alpha regulatory subunit
- cAMP-dependent protein kinase type II-beta regulatory subunit
- cAMP-dependent protein kinase type II-alpha regulatory subunit
- Hormone-sensitive lipase
- cAMP-dependent protein kinase catalytic subunit PRKX
- Putative serine/threonine-protein kinase PRKY
- G-protein coupled receptor 161
Sequence:
MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV
Protein: Chromatin structure-remodeling complex protein RSC8 (A0A1D8PFW3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- RSC chromatin remodeling complex ATPase subunit
- Chromatin structure-remodeling complex subunit SFH1
- Bromo domain-containing protein
- Npl6p
- Uncharacterized protein
- Uncharacterized protein
- Chromatin structure-remodeling complex protein RSC58
- Chromatin structure-remodeling complex subunit RSC1
- Arp9p
- Actin-related protein 4
Sequence:
MSAEPEIPKVEVPKLEESVTEDTPAPTTDDQNNQTPQVIDVEKLQHEFQESAKRYLVEQTAQVIVPSFAKWFDLSKIHDIEKKSLPDFFVEDGSGYKSSQDYKYIRDFIVNTFRLNPKEYLTITAVRRNLSGDVTNIIRIHQFLEQWGLINYQIDPKTKSSVLGPQYTGHFQITLDAPQGLVPFVPENAELTKATPSNVTKTDDLNNENIPTAKENELPLNLEIRRNVYATGEKKTNYKTNNIVHYSCSICGKDTTEVRYHNLKIKSYMYNPTSTINNASVLCEICYDQGLFPSSFHSSDFIQLKRTEEGEKWSEQEILLLLEGIEMFGTYEPPSSTGPVNVNANLNNQWDKISEHVATKTREQCIIKFIQLPIEDKFLTKLIKEENEKDTTKSVVSQSLVQDIAAKLVSTTEGREFISQNAEENLKHAQLEQTNLVNQVIELTLEKFNLKLKKIDELQANLLKYENQLNLERKQILLERWVQFEKISKLKESNPELSTVLDDLLKPVKINEIHKSVKQSNQTENGDDKMDVDESSNENDDNTSKLPVSVKEPKAYQFWSG
Protein: F-box/LRR-repeat protein fbxl-1 (F-box and leucine-rich repeat protein 1) (P34284)
Organism: Caenorhabditis elegans
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity). Plays a role in regulating the entry into the dauer state. In hermaphrodites, may play a role in modulating the rate of defecation.
Subcellular location: Perikaryon {ECO:0000269|Ref.3}. Cell projection, dendrite {ECO:0000269|Ref.3}. Cell projection, cilium {ECO:0000269|Ref.3}. Cell projection, axon {ECO:0000269|Ref.3}.
Interaction partners:
- Probable geranylgeranyl transferase type-2 subunit beta
- Cullin-1
Sequence:
METAERISAAASAASSRRAKRLAQQAHKTHPVIQAKQNQMYLITTLSPAQVDNSLINRVLPKEVLLKVFSFLDTKALCRSAQVCRSWSILALDGSNWQRVDLFTFQRDVKTAVVENLARRCGGFLKELSLKGCENVHDSALRTFTSRCPNLEHLSLYRCKRVTDASCENLGRYCHKLNYLNLENCSSITDRAMKYIGDGCPNLSYLNISWCDAIQDRGVQIILSNCKSLDTLILRGCEGLTENVFGSVEAHMGAIKKLNLLQCFQLTDITVQNIANGATALEYLCMSNCNQISDRSLVSLGQHSHNLKVLELSGCTLLGDNGFIPLARGCRQLERLDMEDCSLISDHTINSLANNCTALRELSLSHCELITDESIQNLASKHRETLNVLELDNCPQLTDSTLSHLRHCKALKRIDLYDCQNVSKEAIVRFQHHRPNIEIHAYFAPVTPPTDQVVNRGGICRCCVIL