wanglab/gogpt-training-data huggingface dataset:
Protein: Alarmin release inhibitor (HpARI) (A0A3P7XL18)
Organism: Heligmosomoides polygyrus (Parasitic roundworm)
Function: Secreted protein which suppresses the host allergic response by inhibiting the interaction of host IL33 with its receptor in order to maintain parasitic infection. Binds to both host IL33 and host nuclear DNA and this dual binding blocks the interaction of IL33 with its receptor, and tethers IL33 within necrotic cells, preventing its release, and blocking allergic response initiation.
Subcellular location: Secreted {ECO:0000269|PubMed:29045903}. Host nucleus {ECO:0000269|PubMed:29045903}.
Interaction partners:
Sequence:
MDIIGQVYCFTGAPHTITCLLREQFINWYIKYKRSENYPAFRELVVMYRLFLALGFLTFINAAGQRCRFTDVERDKGYTGMLLKGRLRKTAGNGRTVELICGRGNHNYTCESGVLKESSPRQARCGCKGILEMLFDMPKEERPSPMYDSVTYDPTPNTPTTVGKDGIWNGVDYRNGSTVKPYCDTGPVINGSSKAVCVSGKWVPTLGVCPKMCSIGSLKENGKFVDVTATTKGDELNPPPREQTLIPIVRKVDKDKVQHGVKVVALCKAEDSTTAAEGVQEFECDNGKWKPEPVPCP
Protein: N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase (EC 6.3.2.38) (Aerobactin synthase IucA) (Q47316)
Organism: Escherichia coli
Function: Catalyzes the attachment of a first N-acetyl-N-hydroxylysine to a carboxylic group of citric acid to yield N-citryl-N-acetyl-N-hydroxylysine. Involved in the biosynthesis of the siderophore aerobactin which is a chelator that mediates the high-affinity iron transport systems induced under iron-stressed conditions.
Interaction partners:
Sequence:
MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDEQKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFNRQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLRPWQGEYLFQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDDWTGLRDLNGNIMQESLFSPAWKTLLLEQPQSQTNVLVSLTQAGPHGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
Protein: UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1) (Q91XL3)
Organism: Mus musculus (Mouse)
Function: Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q5PQX0}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8NBZ7}.
Interaction partners:
- UDP-glucose 6-dehydrogenase
- Ubiquitin-like protein FUBI
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
- Beta-1,4-galactosyltransferase 7
- Glycosaminoglycan xylosylkinase
- Xylosyltransferase 1
Sequence:
MVSKGLLRLVSSVNRRRMKLLLGIALFAYAASVWGNFVNMRSIQENGELKIESKIEEIVEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELEYQANNQYIPKPKPARVKKGRTRHS
Protein: Transcription factor AP-2 beta (D4A505)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLVHTYSSMDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTNRHTSGEGPGSKTGDKEEKHRK
Protein: Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein) (Q9H0A9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31429579}.
Interaction partners:
Sequence:
MAEGGELMSRLLSENADLKKQVRLLKENQMLRRLLSQSCQEGGGHDLLPPRAHAYPEAGSPGSGVPDFGRFTSVADTPSQLQTSSLEDLLCSHAPLSSEDDTSPGCAAPSQAPFKAFLSPPEPHSHRGTDRKLSPLLSPLQDSLVDKTLLEPREMVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW
Protein: NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit 4L) (NADH-plastoquinone oxidoreductase subunit 4L) (P0C333)
Organism: Oryza sativa subsp. indica (Rice)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01456}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01456}.
Interaction partners:
- NAD
- NAD
- NAD
- NAD
- Photosystem I iron-sulfur center
- NAD
- NAD
- NAD
- 4Fe-4S ferredoxin-type domain-containing protein
- NAD
Sequence:
MMFEHVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNFLNN
Protein: Straw, isoform D (EC 1.10.3.-, EC 1.16.3.1) (B7YZT1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKAMDLNGFYQTFISFLIWGAFSNFPEVFAVRVANSQQNQPKKENQPDLTPMGSFWQQHVATPSSSTPFDSPFFSATHGLVQTHPSIGGSHSGPAPLNGNSLGSGAPSSILAGTKPALTAGSGYLNSRGSLPTSARYPANKITGTVVEPNPKSPFRHLDFSTSATAELRRNPALSAPDECARACREGEPPRICYYHFTLEYYTVLGAACQVCTPNATNTVWSHCQCVLADGVERGILTANRMIPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGSQYYDGVPFVTQCPIQQGNTFRYQWTGNAGTHFWHAHTGLQKLDGLYGSVVVRQPPSRDPNSHLYDFDLTTHIMLISDWLHEDAAERYPGRLAVNTGQDPESMLINGKGQFRDPNTGFMTNTPLEIFTITPGRRYRFRMINAFASVCPAQVTIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGAYWIQLRGLGECGIRRAQQLAILRYARGPYQPASSPPTYDVGIPQGVILNPLDAICDRKRADAVCVSNLKNAKKVDKGVLVERPDVKIFLPFRFFVYEPKALFIPNTYNRFLVVPSGDHLTSLVDEISYISPPAPPLSQIDDIPPEYFCNGDNRPPNCGPNCECTHMVDIPLGAIVEVVLVDEVQQVNLSHPFHLHGTAFYVVGLGRSPDKSIKKINLKHALELDQMGMLERHFSKPPLKDTIAVPNNGYVVIRFRADNPGYWLFHCHFLFHIVIGMNLIFHIGTTADLPPVPPRFPTCGDHVPPVTWY
Protein: NLR family, apoptosis inhibitory protein 6 (A0A8I5ZWN7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAAQGEAFEERICEFDDDLVSEFSTLLRVDALQVLKRQQEEDHKTRMKMKKGFNAQMRSEAKRLKTFVTYDTFRSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFATRLRKVPIEVHRKLQPECEFLSGKDVGNIGKYDIRVKSPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSAEEIAKYIQTYEGFLHVTGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESPMAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCARPEAMETTSESNHEDGVAVHSSVAGIPTCTSLPSADLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTVYILKKIFSHDIIRVRRFINYFGFHEYLQGIHKTPLFVAGVCADWLQNPSDQPFQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAMSIYHTFLRYVSNHPSSKAGPKVISHLLQLVDEKESPENTSENEDYMKLHPETLLWSQCLRGLLQLSPESFSLFISERLLNIALNFAYQSNTVAACSPVILQFLQGRTLDLKVLNLQYFWDHPETLLLLKSIQVLFNGNNRVQRIDFSLMDKSFEKIQPPTIDQDYAFAFQPMSECQRNLAEKENIIKNYDDMKYQDPLNISSGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFHLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSGTSQIPVKLIQNSPNLHDFHLKCDFLSNCESLMAALASCKKLREIEFSGRCFEAVPFVNILSNFASLKILNLRNQQFPDKETSEKFAQALGSLRNLEELHLPTGDGIHQVAKPIVRRCLQLPCLRVLVFAETLDDDSVLEIAKGATSGGFQNLENLDLTLNHKITEEGYRNFFQALDNLPNLQNLDISRHIPECIQVQASTVKALGQCVSRLPSLTRLGMLSWLLDEEDMKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK
Protein: Probable lipase C1672.09 (EC 3.1.1.-) (O74430)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable lipase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Triacylglycerol lipase ptl3
- Multifunctional tryptophan biosynthesis protein
Sequence:
MIQLPFIQRLKWEEYMALFLGFFFVIFEKLLSCLAFMIHNTLGLFYRSVVRNEIKKRSKKRSRSRSVSLQRAKAIHDAADIREMCKISGYYVEDHLVRTEDDYILCIHRISKDSPGRIGSPHPKKLPVVYCHHGLLMNSEVWVCNVDPRNCLVFDLVNKGYDVWLGNNRGNKYSRQHLRFDSTDKEFWDFSIDDFAQYDIPDTIDYILKTSGQTKLTYIGFSQGTAQAFASLSIHPLLNDKINSLIALAPAISPKGLHNRVVDAFVKARPSILFFLFGRKSILPSAGFWQSFLAPKFFDAVLAYCLSQLFNWSCQNISSYQRLVSFAHLYSYTSVKCLVHWFQIMRSAEFRMYDNDQLGHDYFLKYYKAAKFPTNNIRTPIYLIWGGSDSLVDIQAMLNALPAEVEHVKVDSYEHLDMIWADTVKDYVIPPVLRRLRDIHHPPEHEENDKENREIQKNHIAPRNKPI
Protein: WD repeat domain 5 (WD repeat-containing protein 5) (Wdr5 protein) (Q7ZTX2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Retinoblastoma-binding protein 5.
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Protein dpy-30 homolog
- Histone H3.2
- Histone H3
- Histone-lysine N-methyltransferase
- Lysine
- Lethal
- Histone-lysine N-methyltransferase SETD1B-A
- Nuclear receptor coactivator 6
Sequence:
MATEEKKPDTEATKTQPASAASASQSKSAPVKPNYTLKFTLAGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
Protein: Photosystem I iron-sulfur center (EC 1.97.1.12) (9 kDa polypeptide) (PSI-C) (Photosystem I subunit VII) (PsaC) (Q6ENA6)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01303}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01303}; Stromal side {ECO:0000255|HAMAP-Rule:MF_01303}.
Interaction partners:
- NAD
- NAD
- NAD
- Photosystem I P700 chlorophyll a apoprotein A1
- NAD
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Uncharacterized protein
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem II CP47 reaction center protein
- NADH dehydrogenase flavoprotein 2
Sequence:
MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
Protein: Golgi-associated kinase 1A (Protein FAM198A) (Q3UY90)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000269|PubMed:30188967}. Endoplasmic reticulum {ECO:0000269|PubMed:30188967}. Golgi apparatus {ECO:0000269|PubMed:30188967}. Membrane, caveola {ECO:0000269|PubMed:30188967}. Note=Requires caveolae biogenesis to be secreted from the endoplasmic reticulum going through the Golgi apparatus where is post-translationally processed to the mature form. {ECO:0000269|PubMed:30188967}.
Interaction partners:
- Glycosaminoglycan xylosylkinase
- Four-jointed box protein 1
Sequence:
MVSWIWRRLRGKKRSVMAFCLLMVLSAVAVIHFPPGHPASTPGLNPMEPRGEVGASDPRIQQTLNSSLRQPARNLGHWTGQALPRNPILVCAKKQSRRRQVDRSRHPLSVRRDAILSAQDRELLLEGEVRDAGGAALGQPGHNGLVQETQSKTVTMVVPLTERSHESFQAQRDTAAASFRPWPADGRDPLPGAKNGVLTGGKAGSATSGSEAPWWSSSAEDLQKSPWCGTETPGLAGTAAWGQVPPWFMEHDAQTLRLLVHGKVVGKARVPAHGQVLQVGLSAGDALQDISPLRLSQFCSQGLCGLIKRSKDLHEVLSFHLDRVLGLQRSLPAVARSFHSPLLPYRYTDGSVRPIIWWAPDVQHLRDPDEDQNSLALGWLQYQALLARGCKWPGQIPCLGIHHAEWARLALFDFLLQVHDRLDRYCCGFEPEPSDPCVEEGLREKCRNPEELRLVHILVRSSDPSRLVYIDNAGNLQHPEDKLNFRLLEGIDGFPESAVKVLASGCLQNLLFKSLQMDQVFWESQGGAAGLKHVLETLESRGQILLRHIKKHNLTLFRDKDP
Protein: HCLS1-associated protein X-1 (HS1-associating protein X-1) (HAX-1) (HS1-binding protein 1) (HSP1BP-1) (O35387)
Organism: Mus musculus (Mouse)
Function: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:16814492, ECO:0000269|PubMed:26915802}. Endoplasmic reticulum {ECO:0000269|PubMed:10760273}. Nucleus membrane {ECO:0000305|PubMed:16814492}. Cytoplasmic vesicle {ECO:0000269|PubMed:10760273, ECO:0000269|PubMed:16814492}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:O00165}. Cell membrane {ECO:0000250|UniProtKB:O00165}; Peripheral membrane protein {ECO:0000250|UniProtKB:O00165}; Cytoplasmic side {ECO:0000250|UniProtKB:O00165}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:Q7TSE9}. Cytoplasm, P-body {ECO:0000250|UniProtKB:O00165}. Cytoplasm {ECO:0000250|UniProtKB:O00165}. Nucleus {ECO:0000250|UniProtKB:O00165}. Note=Predominantly cytoplasmic. Also detected in the nucleus when nuclear export is inhibited (in vitro). {ECO:0000250|UniProtKB:O00165}.
Interaction partners:
- Hematopoietic lineage cell-specific protein
- Src substrate cortactin
- NADH-ubiquinone oxidoreductase chain 1
Sequence:
MSVFDLFRGFFGFPGPRSHRDPFFGGMTRDDDDDDDDDDEAEEDRGAWGRESYAFDGSQPPEEFGFSFSPRGGMRFHGNFGFDDLVRDFNSIFSEMGAWTLPSHSPELPGPESETPGERLREGQTLRDSMLKYPDSHQPRIFEGVLESHAKPESPKPAPDWGSQGPFHRLDDTWPVSPHSRAKEDKDLDSQVSQEGLGPLLQPQPKSYFKSISVTKITKPDGTVEERRTVVDSEGRRETTVTHQEAHDSSRSDPDSQRSSALDDPFSILDLLLGRWFRSR
Protein: Cytohesin 4 (B1AHH6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDLCHPEPAELSSGETEELQRIKWHRKQLLEDIQKLKDEIADVFAQIDCFESAEESRMAQKEKELCIGRKKFNMDPAKGIQYFIEHKLLTPDVQDIARFLYKGEGLNKTAIGTYLGERDPINLQVLQAFVDCHEFANLNLVQALRFREGASDLGFGG
Protein: CILiary localization (O44754)
Organism: Caenorhabditis elegans
Interaction partners:
- Kinesin-like protein
- Location of vulva defective 1
- EB domain-containing protein
- EGF-like domain-containing protein
- Cysteine-rich transmembrane CYSTM domain-containing protein
- VWFA domain-containing protein
- Tubulin polyglutamylase ttll-11
- Tubulin alpha chain
- Secreted protein
- Polycystin-2
Sequence:
MGSSPSKRSDPVEDIRKEKPGPVEKWADPVERKSRDDEAKGETPKQKGTGKRNAKVTPSNESDAVPKGGKLKLTEGVVQDYINIEKAINRLERKNVLKKFESQTIYADNLKNTVEQLEAVLKELKKQTEREKTDLKNIEQPSVRDYLKQQGQWDDRYLKEKAEYEDAMVRQETVQKELNIARVNYDNAVKIQEIYKQQTDNLNALYEEQDKMLEAIFGTDYASEKENVLEGEVDDMVDWQQRVSLAMFKWANGRVLLVHALTQLTFGINRWQDVQKIEKENERGRYFAAAEARNNFVAAAQNVQSCRMYLNKVDFPYGTEKEIALLEDTVNKAFRNVDNDSEMKKALKVFQETQQKVAALIQWFDKVINDTIRKDLDQANNELIKKQKALREERLTLMKKLAKAQLDIDMKIDYDDVADDELERELKELERQALRDVEKLKEADVQGILDLGKSDGHIVTPLNKLAPLPSKDALFGDVKQKLDEYDETRKQFERRNNLQREKQAMALQEKLKLRQQKNRRNRKERRDSIGTPPLEQPVKSGKKKSAHH
Protein: Gustatory receptor for sugar taste 43a (Q9V4K2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr43a is the main sugar receptor in larvae. Functions as a narrowly tuned fructose receptor in taste neurons but also as a fructose receptor in the brain. Necessary and sufficient to sense hemolymph fructose and promote feeding in hungry flies but suppress feeding in satiated flies.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Gustatory receptor 5a for trehalose
- Gustatory receptor for sugar taste 64a
- Gustatory receptor for sugar taste 61a
- Gustatory receptor for sugar taste 64f
- Gustatory receptor for bitter taste 66a
- Gustatory receptor for sugar taste 64e
- Glycine--tRNA ligase
- Gustatory and pheromone receptor 33a
- Gustatory receptor for sugar taste 64c
- Putative gustatory receptor 28a
Sequence:
MEISQPSIGIFYISKVLALAPYATVRNSKGRVEIGRSWLFTVYSATLTVVMVFLTYRGLLFDANSEIPVRMKSATSKVVTALDVSVVVMAIVSGVYCGLFSLNDTLELNDRLNKIDNTLNAYNNFRRDRWRALGMAAVSLLAISILVGLDVGTWMRIAQDMNIAQSDTELNVHWYIPFYSLYFILTGLQVNIANTAYGLGRRFGRLNRMLSSSFLAENNATSAIKPQKVSTVKNVSVNRPAMPSALHASLTKLNGETLPSEAAAKNKGLLLKSLADSHESLGKCVHLLSNSFGIAVLFILVSCLLHLVATAYFLFLELLSKRDNGYLWVQMLWICFHFLRLLMVVEPCHLAARESRKTIQIVCEIERKVHEPILAEAVKKFWQQLLVVDADFSACGLCRVNRTILTSFASAIATYLVILIQFQRTNG
Protein: Translation machinery-associated protein 20 (P89886)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in translation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Translation machinery-associated protein 22
- Translation machinery-associated protein 64
- Obg-like ATPase 1
- Obg-like ATPase homolog
- Eukaryotic translation initiation factor eIF-1
- Uncharacterized protein YPR063C
- Malonyl CoA-acyl carrier protein transacylase, mitochondrial
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS15
Sequence:
MFKKFTREDVHSRSKVKSSIQRTLKAKLVKQYPKIEDVIDELIPKKSQIELIKCEDKIQLYSVDGEVLFFQKFDELIPSLKLVHKFPEAYPTVQVDRGAIKFVLSGANIMCPGLTSAGADLPPAPGYEKGTIVVINAENKENALAIGELMMGTEEIKSVNKGHSIELIHHLGDPLWNFSVE
Protein: Cardiolipin synthase (CMP-forming) / mitochondrial hydrolase fusion protein [Cleaved into: Mitochondrial hydrolase (EC 3.-.-.-); Cardiolipin synthase (CMP-forming) (CLS) (EC 2.7.8.41)] (O13899)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.; SUBCELLULAR LOCATION: [Cardiolipin synthase (CMP-forming)]: Mitochondrion inner membrane {ECO:0000305|PubMed:29958934}; Multi-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Mitochondrial hydrolase]: Mitochondrion {ECO:0000269|PubMed:29958934}.
Interaction partners:
- Abhydrolase domain-containing protein C22H12.03
- Rsm22-cox11 tandem protein 1
- ATPase synthesis protein 25
- Putative phosphatidate cytidylyltransferase
- Rsm22-cox11 tandem protein 2
- Probable phosphoserine phosphatase
- Amino-acid acetyltransferase, mitochondrial
- Methylenetetrahydrofolate dehydrogenase [NAD
- Probable thymidylate synthase
- Altered inheritance of mitochondria protein 19 homolog
Sequence:
MLHTINYRSWHLAARQLGRSTFRKFTTESSTKSPIADVCFAFDSIDGVLIRGGRGLKEGTKTLKFLQKNNIPFILLTNGGGMHESVRAQRLSKTLSVSLTEDDFCQSHTPFRALADKYKHVLVLGGKDNSVRETAEKYGFKSVINELDVIAKLGTPFWPFTSFNEEDIKDAKDFDVTRPIEAVFTYVDPVRLGLDLQLVMELGQSKNGVLGTVSKTANEGPDIYFSNADLIWPNEYPLPRLGQGAFAICCESVFKELTGKDLRNTKYGKPHKLTYDYAKNILMKKHKTLGITNPPKEIFMVGDNPESDIRGANNYGWTSILVRTGIFQGDNSPKYSAKHVSDNVWEGVRWALSKHVPAAKLNKSMGEVRGFHTSSRVLNTVTKSNNSKPIQRPLRENIFTLPNLLTFSRLLSAPLIAYLYIYDYTKAAACFFLYAGFTDLVDGYIARKFDLGSIAGTVLDPLADKTLMTCLTICLAVRETMPLTLASLIIGRDVLLVSAVSYLRYKSLPAPKTFRRFFDFAIPTTELKPTRISKWNTALQLLLLGLLITEPILPFDASFAKSPLFYIVGCTTIASGASYCISRNTFRNIGKSKLQ
Protein: Putative phagocytic receptor 1b (SrfA-induced gene C protein) (Q54ZW0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in adhesion and phagocytosis of hydrophilic particles.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Membrane-associated sulfotransferase kil1
Sequence:
MRLQILLIYLICIIVSSIVLVESSNKHHFKENDEVPFYVNNVGPYSNPTETYEFYTLPFCKPSSISYKKTKLGEILQGDSAVLSDYQFPFKSSFENKQLCEYTLKKEDIEKFKKAIGEYYYAEMIYDDLPIFSFVGTVDDSDLTNIRYYLYNHIPFEFDYNGDQVIRVNIDTEHIKVIELSDQDEITLKLTYSAKWQPTEHEFSKRMDLYEEFFTKELEIHWLSVMNSFFLVVLLTAFLAIMIMKILKNDYSRYSKTDEEEDSDYQEDYGWKLVHGDVFRFPPYKNVFSAFYGIGWQFISIVCGILALSLFGMFYPNNGGNMYTAGIVLYALTSGISGYQSAKMYKNMGGNKWAWNIVLTATLFVAPLFIVVILSNTVAITWHSTVALPILTMIEVITIWLFVGFPLTVVGGIAGRRLSENFEAPCRTKNFPREVPPIQWYRRLPCQILIAGFLPFSAIYIELFYIFNSVWGHSTYTLYGILCLVFLILINVTVCITVALTYFQLSMEDHKWWWNSFINGGSTVVFIYMYSIYYYYYISHMYGLLQATFYFTYMLIVCFFFFILLGTVGFYSSLIFVKRIYRNLKSD
Protein: Dof zinc finger protein (F4IWU4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00071, ECO:0000256|RuleBase:RU369094}.
Interaction partners:
Sequence:
MVFSSLPVNQFDSQNWQQMISILVFFSTSRLFKKLFLVDKNLFSCLLQGLMYNVFLTGLIFSLQGNQHQLECVTTDQNPNNYLRQLSSPPTSQVAGSSQARVNSMVERARIAKVPLPEAALNCPRCDSTNTKFCYFNNYSLTQPRHFCKTCRRYWTRGGSLRNVPVGGGFRRNKRSKSRSKSTVVVSTDNTTSTSSLTSRPSYSNPSKFHSYGQIPEFNSNLPILPPLQSLGDYNSSNTGLDFGGTQISNMISGMSSSGGILDAWRIPPSQQAQQFPFLINTTGLVQSSNALYPLLEGGVSATQTRNVKAEENDQDRGRDGDGVNNLSRNFLGNININSGRNEEYTSWGGNSSWTGFTSNNSTGHLSF
Protein: Growth hormone receptor isoform 1 (Growth hormone receptor isoform 1 precursor isoform X1) (Q5J7P6)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Somatolactin
- Growth hormone 2
- Somatotropin
- Somatolactin beta
- Suppressor of cytokine signaling 2
- Suppressor of cytokine signaling 2
Sequence:
MATSHILFICLLLILAVLSQEPPTSKQALSQIRPQITGCVSHDMNTFRCRWNVGVFQNLTEPRDLRIFYYINDKNISPKEWDECPHYADRTDECFFNESYTKVWMTYSVQLRSGDQDILYDEVIFTVEDIVEPDPPIALNWTLLNVGLTGSHFDIMLSWEPPHSADVSMGWMTLQYEVQYREVNSTLWRTVDLEKGMQRSLYGLRTNTDNEVRVRCKTLASRNFGEFSDSIFIHIPTKESRLPVTVLLVFAALGLAVILMLVVYSQQQKLMVILLPPIPGPKIKGIDPELLKKGKLAELTSILGGIPDLRPELYSDDPWVEFIELDMEEPNNRLTVLDTQCLMDHCASSDCPPITIGFRDDDSGRASCCDPDLPDPEASPFHSLLSNTSCALEPSCLASTKASSPVQTPTTEDSPWAAPGREDLYTQVNEVRLTGEVLLTPEEQRKVEENAEKDAKEKEKEKKRKEFQLLVVNADVGGYTSELDAGKLSARLPTGRASQPASTEDSSLVQGQPFGEYQSLYFEAEMPPIPPASPVSPLPPVSAYTMVEGVDRQNSLLLKPGPTPAPQTVLTKLPLPTPTPEGYLTPDLLGNITP
Protein: tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (PSU-I) (tRNA-uridine isomerase I) (P07649)
Organism: Escherichia coli (strain K12)
Function: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
Interaction partners:
- tRNA pseudouridine synthase B
- tRNA pseudouridine synthase D
- Large ribosomal subunit protein bL17
- Dual-specificity RNA pseudouridine synthase RluA
- Ribosomal small subunit pseudouridine synthase A
- DNA-directed RNA polymerase subunit alpha
- USG-1 protein
- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- Protein DedA
- tRNA dimethylallyltransferase
Sequence:
MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD