wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein (Q384J2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- BING4 C-terminal domain-containing protein
- AATF leucine zipper-containing domain-containing protein
- Uncharacterized protein
- U3 small nucleolar RNA-associated protein 18
- HEAT repeat-containing protein 1
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- U3 small nucleolar RNA-associated protein 6 N-terminal domain-containing protein
- KRR1 small subunit processome component
- Bms1-type G domain-containing protein
- U3 small nucleolar ribonucleoprotein protein MPP10, putative
Sequence:
MFRRAYHTNLGNAHLYHPLHQPKFHRKDTNLRVQRKQGHTAHMTSPHLLTFSQEAVCVAEEFGVAFYAPKNLKKFQVERFNGVRIAGIYATKASDGGSHLHVVDVEANWFLVSLSRVEVVSSSSIELSEENSVKQSESSRHSEECARRLPNTEGILEAHFHEAGGVLHCVVLTRWGAYETVLTNTSRIVARNIISFPFEMRNCFMSVGRTSGLVVVCQRSEKWLRYSLFEQRDNERIRMFDSPVNVQSFAVNPISNSVVLGGTRGEMVLYPSITEKNYFSDHWHHTPLTALSFSIDGKAFYSGAREGMILVWNTSSYTYKKVSCGLGCINSIAVPTGNGSRVLLSCAESTIAVLDLLQMQVEKFVEGVQWSTDESCSGLVVSQWMGQPAVILTGLPNVVRVCDPFTQQAIYSLHISSQMETIPSPPRHGIQYVGLLNNNRTIVTYEEFSGVSLPSLLRFWAYSSDSKRHEESMTICSPHRSQVLALTTDDTQQRVFTLSGEAMKCWVECKEDLNDAHAIGKKTWGNQSSCVTPSRLVQDLIISHDGSLCFISDDNVHVYNVKALHPGQPWQRVLTLTQHFSLSPLKNLTLLHECRALVATDAERVYFWSLAKPRRQATIWKDKGVGGKAAGITAMCGFSVNSVLVATERCNLWELSAADVNEMGKVVGQANSATEHRITFMKPLSLLKQPDRIAVVDSVSGFRVMHVSLEGKGGVNVQQFERTTARDESNETLSSLKQYFQEAPVRSNNFDGADENASTILDRASQVAEAQKWLVGVLADSAYTAPPMSALLSSYLQRRAGVATF
Protein: Melanoma-associated antigen C3 (Cancer/testis antigen 7.2) (CT7.2) (Hepatocellular carcinoma-associated antigen 2) (MAGE-C3 antigen) (Q8TD91)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLLPCHWVLDATFSDGSLGQWVKNTCATYALSPVVLPPQPQPRKKATDKDYSAFHLGHLREVRLFLRGGTSDQRMDSLVLCPTYFKLWRTLSGSPGLQLSDLHFGSQPEGKFSLRRAVSVKQREEPQDWPLNEKRTLWKDSDLPTWRRGTGYTLSLPAVSPGKRLWGEKAGSLPESEPLFTYTLDEKVDKLVQFLLLKYQAKEPLTRAEMQMNVINTYTGYFPMIFRKAREFIEILFGISLTEVDPDHFYVFVNTLDLTCEGSLSDEQGMPQNRLLILILSVIFIKGNCASEEVIWEVLNAIGPWSALAGFADVLSRLALWESEGPEAFCEESGLRSAEGSVLDLANPQGLAGHRQEDGRRGLTEASPQQKKGGEDEDMPAAGMPPLPQSPPEIPPQGPPKISPQGPPQSPPQSPLDSCSSPLLWTRLDEESSSEEEDTATWHALPESESLPRYALDEKVAELVQFLLLKYQTKEPVTKAEMLTTVIKKYKDYFPMIFGKAHEFIELIFGIALTDMDPDNHSYFFEDTLDLTYEGSLIDDQGMPKNCLLILILSMIFIKGSCVPEEVIWEVLSAIGPIQRPAREVLEFLSKLSSIIPSAFPSWYMDALKDMEDRAQAIIDTTDDATAMASASPSVMSTNFCPE
Protein: Exosome complex component RRP45 (Exosome component 9) (Q8T4A9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- FI06805p
- Exosome complex component 10 homolog
- Nuclear nucleic acid-binding protein C1D
- Csl4
- Ribosomal RNA-processing protein 42
- Exosome complex component RRP4
- FI07225p
- FI01414p
- Exosome complex exonuclease RRP44
- RNA helicase
Sequence:
MFHNSNFFEPGKSKPERSFVQLAVKQNQRLDGRRSNESRDVELTFGKDWGSVAVSMGDTKVLAQVTCEMGPPALSRPNEGKIHLNVYLGGVAFLDEAHTTHDQRSLKLNSLLERTFRSSRSIDLESLCVAVEKHVWCIRVNVNVLNHDGNLYDASTIATLAALMHFRRPDVWYKDGELRIFKKKEREFIPLLFHHYPVSVTYCVYKSSVQPILDPTLLEENAADSVIVLSFNSFQELCSLTAGGTAPTNARIIMQCARNAAVRCKSLLNFVRKALALDEECRSQGDQSVDGLVALILNTEHKLSYNKLMGRQKQEQQPPPSEKMQLDNNESSETPVANEEPSKEESAGAPMDTSDWLPHDEDSQELPMRSEASPSKAGLKGKQSRGKYKANKKTPPRKQNHSDSEEEAKRYI
Protein: Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase) (P30137)
Organism: Escherichia coli (strain K12)
Function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Interaction partners:
- Hydroxyethylthiazole kinase
- Thiazole synthase
- Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
- Sulfur carrier protein ThiS adenylyltransferase
- 2-iminoacetate synthase
- Phosphomethylpyrimidine synthase
- Thiamine-monophosphate kinase
- Sulfur carrier protein ThiS
- Thiamine kinase
- Small ribosomal subunit biogenesis GTPase RsgA
Sequence:
MYQPDFPPVPFRSGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
Protein: Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) (O00291)
Organism: Homo sapiens (Human)
Function: Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner (By similarity). Regulates presynaptic nerve terminal activity (By similarity). Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
Subcellular location: Cytoplasm. Nucleus. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Note=Shuttles between cytoplasm and nucleus. Nuclear translocation can be induced by AR.
Interaction partners:
- Huntingtin
- Clathrin heavy chain 1
- Clathrin light chain B
- Intraflagellar transport protein 57 homolog
- Clathrin heavy chain 2
- Clathrin light chain A
- Caspase-3
- Caspase-8
- AP-2 complex subunit alpha-1
- Huntingtin-interacting protein 1-related protein
Sequence:
MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTLQEVVTEKE
Protein: Phospholipase A1-Igamma1, chloroplastic (EC 3.1.1.-) (DAD1-like lipase 4) (Q941F1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acylhydrolase with a broad specificity. Catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position. Moderate activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and triacylglycerol (TAG). May display dual sn-1/sn-2 substrate specificity. Could be involved in early wound response.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:19527719}.
Interaction partners:
- Elicitor peptide 4
- Phospholipase A I
Sequence:
MATIPSHNLRPHTTNQRTQYSLSFRPHFSRSTLITFPARSSPARAMSRTDEEASISTRLEQESYGLTTAEDIRRRDGEAKESKRLRDTWRKIQGEDDWAGLMDPMDPVLRSELIRYGEMAQACYDAFDFDPFSRYCGSCRFTRRHLFDSLGIIDSGYEVARYLYATSNINLPNFFSKSRWSKVWSKNANWMGYVAVSDDNEATRCRLGRRDIAIAWRGTVTRLEWIADLKDFLKPVSGNGFRCPDPAVKAESGFLDLYTDKDTSCNFSKFSAREQVLTEVKRLVERYGDEEGEELSITVTGHSLGGALAVLSAYDVAEMGVNRTRKGKVIPVTAFTYGGPRVGNIRFKERIEKLGVKVLRVVNEHDVVAKSPGLFLNERAPQALMKLAGGLPWCYSHVGEMLPLDHQKSPFLKPTVDLSTAHNLEALLHLLDGYHGKGQRFVLSSGRDPALVNKASDFLKDHFMVPPYWRQDANKGMVRNTDGRWIQPDRIRADDQHAPDIHQLLTQLHHPSQLL
Protein: Protein GOLM2 (Cancer susceptibility candidate gene 4 protein) (CASC4) (Golgi membrane protein 2) (Q6P4E1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQHFNDVL
Protein: Transcription factor bHLH80 (Basic helix-loop-helix protein 80) (AtbHLH80) (bHLH 80) (Transcription factor EN 71) (bHLH transcription factor bHLH080) (Q9C8P8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor GLABRA 3
- Adagio protein 3
Sequence:
MQSTHISGGSSGGGGGGGGEVSRSGLSRIRSAPATWIETLLEEDEEEGLKPNLCLTELLTGNNNSGGVITSRDDSFEFLSSVEQGLYNHHQGGGFHRQNSSPADFLSGSGSGTDGYFSNFGIPANYDYLSTNVDISPTKRSRDMETQFSSQLKEEQMSGGISGMMDMNMDKIFEDSVPCRVRAKRGCATHPRSIAERVRRTRISDRIRRLQELVPNMDKQTNTADMLEEAVEYVKALQSQIQELTEQQKRCKCKPKEEQ
Protein: Vacuolar import and degradation protein 27 (P40157)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a role in the negative regulation of gluconeogenesis. Required for vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- PX domain-containing protein LEC1
Sequence:
MNILKKFMESGNKPELITIPSGQFNLLRSKNSPKAALECIYNNATLSVRKIGKFDYELAVYRVEDDSEGGTGDEAENFEDDTISVLSTQSKKKEEEWSVEISDKIMFHKTWDKQGNVALVWENLRGDEQDEKVQFVVAADVSFSDVEQFIQTVYRCQFEVRNKKSSLTASADDLKEIEHRSTRLFVQDDDDELDSSSDDFQDAKDTSFEHEKESEILERTPSPLKKVPEGEYCCLVMSSLYMYDPIQEKFILQEPVVKVAIIDTGKYEFWLAIEGKDNRLGTQVAPNINPTFELATDAFLFNYTLQNITLSYMLKFKDLDKCIQFRFAWVKCLWMTLNKETWTDVPEKEKDYILDSSSVPLEKQFDDILHIDDRSNEERDKESSESENDSEDEDDENDHSKRIISSEAFEEPRRATSKGNSSLTVAFRNNRSYVTRDNRIGVFKTDDEDDSLEFVAAIKNISNLGGKSIDPHKPMLYMEDRNLILTDGENENKLYKMDIERGKVIEEWSTGDKNVVQYGPTKKFDQMTPEQTIVGVSQKGVFKIDPRINGKNKIAVDESKDYVGKYNFSSIGTTESGYIAIGSEKGDIKLYDRLGIRAKTAIPSLGQAIKFITTSADGKWLLATCESTLLLMDLKIKDGKNAGNIGFLKSFPASENVKTYVLKIRPEHSASILTYTKKPIRFTKAYFNTGIGQQEQTIVTSTGPYAISWSLKGILNQDGSNNYPYRIRRYNADVVADNFEFGSDKKVIVALKDDVSLSKVKSFKQPSKGVLMPSASLQDFYG
Protein: NAD-dependent protein deacetylase sirtuin-1 isoform a (Sirtuin 1) (A7LKB1)
Organism: Sus scrofa (Pig)
Interaction partners:
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Cellular tumor antigen p53
- Forkhead box protein O1
- Forkhead box protein O1
- Peroxisome proliferator-activated receptor gamma
- Nicotinamide phosphoribosyltransferase
- RELA proto-oncogene, NF-kB subunit
- Nicotinamide-nucleotide adenylyltransferase
- Nicotinamide nucleotide adenylyltransferase 2.
- Glutamine-dependent NAD
Sequence:
MADEAALALQPGGSPSAVAAEREAPSPPAGEPLRKKPRRDGPGVGRSPGEPGGAALERELPAAAGGCPAAAVLWRETAAGGEREAQAAAAAGEGNNGPGLQGLSREAPPADDFYDDDDDDEGEEEEEAAAAAAIGYRDNLLFGDEIVTNGFHSCESDEDDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEGSSSPERTSPPASSVTLPLLDQATKSNVDDLDVSESKDCVEEKSQEVQTSRSIESVKEPMESPGLKNVACSNGEKNERTSVAETVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSESGTCQSPSLEEPMEDESEIEEFYNGLEDDADVNMRAGGTGFGADGSDQEAVNEAISMKQEATGVNYPSNKS
Protein: Cycloartenol synthase (KdCAS) (EC 5.4.99.8) (E2IUB0)
Organism: Kalanchoe daigremontiana (Devil's backbone) (Bryophyllum daigremontianum)
Function: Oxidosqualene cyclase which catalyzes the conversion of oxidosqualene to cycloartenol.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MWKLKIADAGGSQWLRSVNNHIGRQIWDFDPALGSPEELAQIEDARDNFARHRFDKKHSADLLMRFQLTKENPQSDLLPKVNIGKIEDITEDAVTNTLRRAINFHSTTQAHDGHWPGDYGGPLFLMPGLVITLSITGALNAVLSKEHKKEMCRYLYNHQNEDGGWGLHIEGPSTMFGSVLNYVTLRLLGEDVNGGDGEIERARKWILDHGGATAITSWGKMWLSVLGVFEWCGNNPLPPEMWLFPYYLPVHPGRMWCHCRMVYLPMSYLYGKRFVGPITPTVLSLRKELFTVPYHEIDWNEARSLCAKEDLYYPHPVVQDILWATLHKVVEPVLLNWPGKKLREKALCSAIEHIHYEDENTRYICIGPVNKVLNMLCCWVEDPNSEAFKLHIPRLYDYLWIAEDGMKMQGYNGSQLWDTAFSVQAIVATKLVEEFSSTISKAHEFMKNSQVLEDYPGDLSYWYRHISKGAWPFSTADHGWPISDCTAEGLKVVLKLSQFPAELVGAPLSAKLVYNAVNVILSLQNIDGGFATYELTRSYSWMELLNPAETFGDIVIDYPYVECTSAALQSLVLFKKLHPEHRKEEVELCIKKAAAFIEKIQESDGSWYGSWAVCFTYGTWFGVLGLVAAGRNYKNSPSIRKACDFLLSKQLASGGWGESYLSCQNKVYTNIPGGRSHVVNTGWAMLALIGAGQAERDPVPLHRAAKFLIESQLENGDFPQQEIMGVFNKNCMISYAAYRNIFPIWALGEYRCKVLNASRGQMKT
Protein: Aluminum tubes, isoform G (Aluminum tubes, isoform I) (LD29525p) (Q960Y8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Odorant receptor 59a
Sequence:
MDFHILIVIGCVVSASLLSFLFINKIFRRKTFEEVVAEKRALSANLYKAAGGAATKKPKKKELKREKKQRQREQQRDVNNEPEPEEAEDYSDGQSEGQGSVAGEEPGLSKQHVEFEPDAEVLTDQRRPSSVAEKENQPSGAGKKGKKDKRNGANNKTAGILVNKNETVAVKPAANAEETPTLNNFETKIPKDVVELKKQEQKERKEDNNNKQQSQKKIAGGNVSKKEKVVAVETEAPVVTKQILKQQQQQQNGSPKTQHNQANNKTKQQQQNKKQNQKETLTGKDLAHALDKLADHQNQTIGVNALMNVFSRAELNRSEIQILIDYLLNKQQDMPASHSEWSDDICQKLKRQLEEKEKLLAEEQEASIGIQAKLRELRQEVNTERAQMHARNQAYIDKLQGKEQELAALNQELSSLNDKLTLERQQLTTLRREKQANSQDLVQLQHLQQDLAHKEKCLAEMTAFVNAETQQKNEVIQQQAQQLQALELQREELEARQNNSIFELEQRKQLEAENADLKQELSAVQQTQSELQRVHAAELQELRQNLSVLEARNVALSQQLTQAANSAVQATAAQSEQAQVQTEALAQKQQELSALRSQVGSLTDAHAQQQKQANALQSQLQEAQQRAEQLQAKEQHLQQELQEQREKNNDVRMKNWKLIEALQNAEALTAKTKTNSAQSVGQQHKELQLQQQKAVAANGGGSASSAKSEQQRIRDLYQRLYPDAVKAQSGNALQASFDQWLEQVLATHVKQQQDKLRQKLDAEKSEKQSSSSHKSTQSSNSSSSNHNSTHNNISSNNSSSNSQSSSAAEQQELHKQNLQLRECNDKLTQLVTKTTNTLMDLEERAREQDEHWRGIVEQKEQLILTLQQHASNGE
Protein: Calmodulin (CaM) (P62149)
Organism: Gallus gallus (Chicken)
Function: Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.
Interaction partners:
- Caldesmon 1
- Unconventional myosin-Va
- Sodium channel protein
- Calponin
- Myosin light chain kinase, smooth muscle
- Calponin
- calcium/calmodulin-dependent protein kinase
- Serine/threonine-protein phosphatase.
- Protein kinase domain-containing protein.
- Actin, cytoplasmic 1
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
Protein: Metallothionein (MT) (P68498)
Organism: Meleagris gallopavo (Wild turkey)
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Interaction partners:
Sequence:
MDPQDCTCAAGDSCSCAGSCKCKNCRCRSCRKSCCSCCPAGCNNCAKGCVCKEPASSKCSCCH
Protein: Protein Wnt-3a (XWnt-3a) (P31285)
Organism: Xenopus laevis (African clawed frog)
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P27467}. Secreted {ECO:0000250|UniProtKB:P27467}.
Interaction partners:
Sequence:
MGCFGYLLLIIGLHQVLATYPIWWSLAVGQQYSSLGTQPIPCGTIPGLVAKQMRFCRNYMEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVNDNLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSATICGCDTHHKGPPGEGWKWGGCSEDMDFGSMVSREFADARENRPDARSAMNRHNNEAGRTSILDHRHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEMVVEKHRESRGWVETLRPKYTFFKPPIERDLIYYESSPNFCEPNPETGSFGTRDRECNVTSHGIDGCDLLCCGRGQNTRTEKRKEKCHCIFHWCCYVSCQECMRVYDVHTCK
Protein: DNA 3'-5' helicase (EC 5.6.2.4) (Q9Y1H2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAHESAVHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITIVFSPLLALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTNLKFLYITPEQAATKFFQDLLQTLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDIYKQLRLHQPVAQFSTPSFRKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEFKDTPKPQRGCGIVYCRTRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFVIHWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSIRFLLQNDAHRARGRGDKELLTERAIKQFEKITEFCERTTCRHKLFSDFFGDPTPDCSGQCDVCKRPKKAEKALEMFHRLCMDDAFKSHISLQDCADLYEGGRPGIKRAAQEYAGGESGSDDDSGQSHSSMAKRAKKESQDFIKQQFNLRKQISAARQLEQETIAQISRVRMAEATEKKIAGLQATHREKYLTALIDALKANVDKCKDEPGQQPKSVLKYNDYEAMSVNMEYDVFRQNKVANMYRHALVKEISTIKKLTEQTKLLPLLVDYIPKPETSSKGAWTGGSVAYFERKLKELEEQRPQSLKEVPKALKDRKGFKQENSKQTSISSFFKKEIKEEPIDSPIQEERVNIKSEQMDLEESTPKDIASNHVKEESVTPESSSSDRELELQPDSIIGERKFKLMSNGDGSYDTHRRKRVSHETQPKEKESIKTKSSMQHLFGSFKSESEESNQSLNGFKTARQMLEENNAKLKGVPEKLPIKDGEKGVLENRADSIGFTSAREMLERSKQREGDDKSSNKLEKLGFISAREMLEKNKLNERCLDKKDVKEKKLESRETKRSLQNNELQHKQEEDRKDKASHRKTSKESLSNLKKEGSDSRVLQKDTKPEKNHQKTDVSKNVVQWLNPYYKRKIATKELFKALAKLLTQRICDGSLGDGDAGKCYIKETFHGLQMINNDQDIEKYFIKSK
Protein: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase) (P25536)
Organism: Escherichia coli (strain K12)
Function: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Can also hydrolyze TTP and the modified nucleotides 5-methyl-UTP (m(5)UTP), pseudo-UTP and 5-methyl-CTP (m(5)CTP). Has weak activity with CTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. Important in maintenance of cell shape.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00528, ECO:0000305}.
Interaction partners:
- Rod shape-determining protein MreD
- Cell shape-determining protein MreC
- Ribonuclease G
- Cell shape-determining protein MreB
- Intermembrane phospholipid transporter YhdP
- Inosine/xanthosine triphosphatase
- Pyridoxal phosphate homeostasis protein
Sequence:
MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQVMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASDEPLDKAGAYGIQGLGGCFVRKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG
Protein: Claudin-23 (Q96B33)
Organism: Homo sapiens (Human)
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Subcellular location: Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Malignant fibrous histiocytoma-amplified sequence 1
- Protein phosphatase 1 regulatory subunit 3B
- Claudin-22
- Claudin-16
- Claudin-11
- Claudin-4
- Claudin-10
- Claudin-20
- Claudin-8
- Claudin-5
Sequence:
MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQDEPNFVLAGLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAPWCDERCRRRRKGPSAGPRRSSVSTIQVEWPEPDLAPAIKYYSDGQHRPPPAQHRKPKPKPKVGFPMPRPRPKAYTNSVDVLDGEGWESQDAPSCSTHPCDSSLPCDSDL
Protein: MIP14634p (Pebble, isoform F) (D2NUE8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDYLFGDYLDSITNTPNTDRRDSLPISFNKRKRKRFSQRIQLEGTPLGSGKRRSSVSDAGLLSVSNSLFDCTTSPDKLESDKLLHAEPEASDATPAKKSMRFNHFMDFYTTESNYVGILDTILNLFKNKLEELAETNDPLLNKSEIKTIFGNFLPIHEVHQSMLEHLRKLHANWREDCLIGDIIIQHRDELIKAYPPYVNFFEQMKEQLQYCDREYPRFHAFLKINQTKPECGRQGLQDLMIRPVQRLPSISLLLNDILKHTTSGNADHGRLEEALKAIKQVTLHINEDKRRTESRMAIFDIFNDIEGCPAHLVSSNRSFILKCEVNELSDSLSGRGDSLVLYLFSDSIELCKRRSKGFNTAKSPSTAKTHKHLKLISLNTIRLVIDISDSPRAFGLLLRGDKEKLYTFTISDEETDKSVYVKKLCNQIAAHTCRTDADKLLICRTSQELEVDISDVNVSTLSKAFKLAAKTRLKVGRAFSFNKTPNKLKRAVSTMMTSPFGSTNSLTPASQLAQMRLASCTNINEVDDEDCASMRSSSPSTQSEMLVVPPLSVQPTRKNKAVVGRI
Protein: Pseudouridylate synthase C18B11.02c (EC 5.4.99.-) (Q09709)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Pseudouridine synthase that catalyzes pseudouridylation of RNAs.
Interaction partners:
- Multisubstrate pseudouridine synthase 7
- tRNA pseudouridine synthase 4
- tRNA modification GTPase mss1
- Large ribosomal subunit protein bL17m
- rRNA methyltransferase 1, mitochondrial
- Putative acyl carrier protein, mitochondrial
- Large ribosomal subunit protein uL24
- Mitochondrial GTPase 1
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL11m
Sequence:
MLKRPKRDPLKDCEYVFKGDGLRRVPPYYYEYITFAKLRWYGKTLLEVFNTEFRDRESGYYEKAIRNGQVKVNNQIGNVDTLIENGYIVSHHAHRHEPPVSDQPVGIVHEDESYVVIDKPAGVPVHPTGRYNHNTVLHILMKENKCSLLYPCNRLDRLTSGLMFFSKSPKAAEEMRVHMISKSLKKEYVARVIGEFPNSGEVICDAPLLTVAPTLGLNRIHPDGKEASTVFKRIAFDGHTSLVLCKPLTGRTHQLRVHLQYLGYPIANDPIYANKRVWGPSLGKNGEGSNESVIMRLSEIGKTETASPLLQYEWYTNETEAEAKARRDKRLGELLTGKHCSECGTPLYSDPSPEELGIWLHALKYESKDWSYKTQLPKWALDVCCRDPNALPIE
Protein: Alpha8 subunit of nicotinic acetylcholine receptor (Neuronal acetylcholine receptor subunit alpha-7-like) (Q03481)
Organism: Gallus gallus (Chicken)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
- Acetylcholine receptor subunit beta
- Neuronal acetylcholine receptor subunit alpha-2
- Uncharacterized protein.
Sequence:
MLTEKCLGFFYSGLCLWASLFLSFFKVSQQGESQRRLYRDLLRNYNRLERPVMNDSQPIVVELQLSLLQIIDVDEKNQVLITNAWLQMYWVDIYLSWDQYEYPGVQNLRFPSDQIWVPDILLYNSADERFDATFHTNVLVNYSGSCQYIPPGILKSTCYIDVRWFPFDVQKCDLKFGSWTHSGWLIDLQMLEADISNYISNGEWDLVGVPGKRNELYYECCKEPYPDVTYTITMRRRTLYYGLNLLIPCVLISGLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASIMVIVGLSVVVTVLVLQFHHHDPQAGKMPRWVRVILLNWCAWFLRMKKPGENIKPLSCKYSYPKHHPSLKNTEMNVLPGHQPSNGNMIYSYHTMENPCCPQNNDLGSKSGKITCPLSEDNEHVQKKALMDTIPVIVKILEEVQFIAMRFRKQDEGEEICSEWKFAAAVIDRLCLVAFTLFAIICTFTILMSAPNFIEAVSKDFT
Protein: Basic protein CKT1R2 (Cysteine-rich perinuclear theca 4) (Q8CH21)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MTRVAKKVHWSRAATAAAAAAKAKRSKLKKKRNPRSKLPKRSRHSLIRSHSRSCCCCLRSRSRTTLKITKKGEQSLRRRIRRRIKRATELRLMRSQMEQSQRELIEPEPTEPLEPNEITVALFSHENANVSEPEEVPPYLDRDLAPNGELASS
Protein: Glycine betaine monooxygenase reductase subunit (EC 1.14.13.251) (Glycine betaine catabolism B) (Q9HTF3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Glycine betaine monooxygenase oxygenase subunit
- DgcB, Dimethylglycine catabolism
- DgcA, Dimethylglycine catabolism
- Electron transfer flavoprotein alpha/beta-subunit N-terminal domain-containing protein
- Sarcosine oxidase alpha subunit
- 4-vinyl reductase 4VR domain-containing protein
- Sarcosine oxidase delta subunit
- Sarcosine oxidase gamma subunit
- Sarcosine oxidase subunit beta subunit beta)
- Glutathione-independent formaldehyde dehydrogenase
Sequence:
MSSNFLNPVTTQTWANGRHLVRCVKVIQETWDVRTFCFMADQPILFFFKPGQFVTLELEIDGEPVMRSYTISSSPSVPYSFSITIKRVPGGRVSNWLHDNLKEGQELPVHGPVGLFNAIDFPADKVLFLSGGVGITPVMSMARWFFDTNANVDMVFVHSARSPKDIIYHRELEHMASRIDNFSLHIICERHGLGEAWAGYRGYLNLRMLELIAPDFLEREIFCCGPTPYMSAVKHLLQGHGYDMSRYHEEAFGPTPPEVRADVRELAAEAAEAPEVPVADQHQVEFTATGKSIRVSPGETVHAAAAKLGLHIPKACGMGICGTCKVMKTAGEVEMEHNGGITDEDVAEGYILSCCSVPKGDVVIDY
Protein: Mnt, isoform G (E1JJD1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSGIGGIGVLLEAAQFLEQHEKLPQAGGGGGSALGVGVALPQQQQQTVHCKSNSIINNNNSSQHNRNSSSSSNGIIATPPFTNGNGNGTVGVGNASAIFNVSVNANGNGLSNGHSSPRSQLAAAATAHDYEYSAAGVANGHSEGRPHVSARDQQDHPQHQQHANHMQIQQHYGYMRSNIGGVIYGLHKDSADSAASSACGAGAGAAAVGMSIASSAPAAGSQLSAHHHTGHGGRRRTTSSNSNGAGTREVHNKLEKERRAQLKECYDLLKKVLPMGDEDRKKTSNLTILDTAHKYVNSLSHEVCEQEAKIEKLAKQKIELQKRLKQLSLRRESPPTDQQIIPQADKAVCLATTATTAPPTAASGHNGTTILFDAGNACATGQLTTVINKTNGGATAAASSKHNGNHTGGATTTLTPAMGIMTIKNGNGSNGNMLAISPTGGHNHQLHQHHNGSPAGSPSGIGATTGATITRGSPTPSTPSPSPSSSSSGVSLSTSFMGGSSSSSSSSSSSSSSSSSSSSSSPTQQQQIITPTATARSVGLKFHGGAGAAVPAGGGSVNGFHQADKDRNYTFLRLSAGTTAQ