wanglab/gogpt-training-data huggingface dataset:
Protein: GLI family zinc finger 3 (F1M9H1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Suppressor of fused homolog
- Kinesin family member 7
- Beta-transducin repeat containing E3 ubiquitin protein ligase
- Kinesin-like protein
- Speckle-type POZ protein, isoform CRA_a.
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- Glycogen synthase kinase-3 beta
- Protein smoothened
- Cullin-3
Sequence:
MEAQSHSSTTTERKKAESSIAKCPTRTDVSEKAVASSTTSNEDESAGQIYHRERRNAITMQPQSVQGLSKISEEPSTSSDERASLIKKEIHGSLPHLAEPSLPYRGTVFAMDPRNGYMEPHYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHVPSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISAARGLSPTDAPHAGVSPAEYYHQMALLTGQRSPYADILPSAATAGAGAIHMEYLHAMDSTRFPSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYPSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQSKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGSRGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCTREFDTQDQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDMHPRPPPPRDSGSHSQSRSPGRPTQGAFGEQKELSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIADLSAIDETPIMDSTISTATTALALQGRRNPAGTKWMEHIKLERLKQVNGMFPRLNPILPSKAPAVSPLIGNGTQSNNNYSSGGPGTLLPSRSDLSGVDFTVLNTLNRRDSNTSTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQGDGLPSLLSLTPVQQYRLKAKYAAATGGPPPTPLPHMEKLSLKTRMALLGEGRDSGVTLPPVHPPRRCSDGGGHTYSRRHLLPHDALANSARRASDPVRTVSENMSLPRVQRFSSLNSFNPPNLPPSVEKRSLVLQNYTRQESTHPRYFQASPCPPSITENVALEALTMDADASLNDEDFLPDDVVQYLNSQNQTGYGQQLQSSISEDGKVAREPEDLDLPGLPDSHVGQQYPALEQPCSEGSKTDLPIQWNEVSSGSSDLSSSKLKCGQRPTVQQARGFGLYSNMVVHPQNLWKVGTGPAGGSQTLGENGSSYSDPEHFAVHSGDGLGPSGDTFHEQAYKTQQYGSQLSRQPLTSSVLDSACGAGIQGSKLKGNSLQENGGLLDFGLSMAPNELADNIVNGIQTQEQMGQGYIAPQLLSGSMQHQGPSRPGQQVLGQVGATSHINIYQGTESCLPGTQDKISQPSSMAVIRGYQPCASYGGSRRQAMPRGSLTLQQGQLSDVSQTSRVNSIKMEAHGQSHQLCSSMQNYSGQFYDQTMGFSQQDRKAGSFSLSEANCLLQENGSENSELLSPGVNQVTSTVDSFESHDLEGVQIDFDAIIDDGDHTSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPSLSMSTTNMAIGDMSSLLTSLAEESKFLAVMQ
Protein: Gibberellin receptor GID1 (EC 3.-.-.-) (Gibberellin-insensitive dwarf protein 1) (Protein GIBBERELLIN INSENSITIVE DWARF1) (Q6L545)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:16193045}.
Interaction partners:
- DELLA protein SLR1
- Protein SLENDER RICE1-LIKE 1
- Protein SLENDER RICE1-LIKE 2
Sequence:
MAGSDEVNRNECKTVVPLHTWVLISNFKLSYNILRRADGTFERDLGEYLDRRVPANARPLEGVSSFDHIIDQSVGLEVRIYRAAAEGDAEEGAAAVTRPILEFLTDAPAAEPFPVIIFFHGGSFVHSSASSTIYDSLCRRFVKLSKGVVVSVNYRRAPEHRYPCAYDDGWTALKWVMSQPFMRSGGDAQARVFLSGDSSGGNIAHHVAVRAADEGVKVCGNILLNAMFGGTERTESERRLDGKYFVTLQDRDWYWKAYLPEDADRDHPACNPFGPNGRRLGGLPFAKSLIIVSGLDLTCDRQLAYADALREDGHHVKVVQCENATVGFYLLPNTVHYHEVMEEISDFLNANLYY
Protein: Uncharacterized protein YjjI (P37342)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Putative glycyl-radical enzyme activating enzyme YjjW
- UPF0253 protein YaeP
- Putative pseudouridine transporter
Sequence:
MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQLPAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLANGSEWLELEGAKDLDDALSLLTILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDEIDVRIKRFWRYLDRTLPDAFMHANIGPSDSPITRAILRADAELKQVSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIANGPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYCQQQIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMFGMYGLAEAVNLLCEKEGIAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGARLPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMREFTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISHEQQMRFSQ
Protein: Leucine-rich repeat-containing protein 19 (Q8BZT5)
Organism: Mus musculus (Mouse)
Function: Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines. In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKVTRFMFWLFSMLLPSVKSQASETEVPCNFSRRNYTLIPEGISTNVTILDLSYNRITLNAADSRVLQMYSLLTELYLMENNIIALYNSSFRNLLNLEILNICGNSISVIQQGSFVGLNELKQLFLCQNKILQLNPDTFVPLNNLKVLNLQGNLIRLFDAPQLPHLEILTLDGNPWNCTCGLLELHNWLNTSNVTLENENMTMCSYPDELKHDSIKSAPFTTECHSTFISTITEDFQSTRNSSFNSSSHNLTWTSEHEPLGKSWAFLVGVVATVLLTSLLIFIAIKCPVWYNILLSYNHHRLEEHEAETYENGLTRNPSSLSQITDTNSEDTTVIFEQLHAFVVDDDGFIEDRYIDINEVHEEK
Protein: Amphiphysin (P49418)
Organism: Homo sapiens (Human)
Function: May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Interaction partners:
- Synaptojanin-1
- Dynamin-1
- Dynamin-2
- Myc box-dependent-interacting protein 1
- Clathrin heavy chain 1
- Synaptojanin-2
- AP-2 complex subunit beta
- Endophilin-A1
- Intersectin-1
- Clathrin heavy chain 2
Sequence:
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
Protein: Rlb (Q3YMU8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDRLKFNNLVISNKKVIQKARAQTIAKIVQKLRKTKEALAKNPDSEKEKIRLRKNTECLAQLKALKYMDMVRQSLLQEGTNPNAVIANERSTPDELGIAMLRLNKLMHGLVDKFVETLKLSTTDKEAKWREEILETSKRRAKIERTEERKRKRKELKEQKAQTKNRLEWLEQNKVVDADVNGATAETPTLQVSKVNDQEIPQSFAKTENSPVLKVKKEKTPKTPAKKERNLQKKQAFDEQINPEITKLSSKKQNLNTIKENNAEPQLEGRPKESKPKPFEKKPAREQKPKPRLERQPSIDEEEPQLDNNRPTHVVDPFFITESGQPYLSSAVVLSGDNDSEADEEQAPPPVKRFRNEDRRSNTYREKPERQPEFKARKPTDDRHPSWLAKQQQKPIIGDFRGKKITFGDDGQAAEIIAPSINQLTATAAPLPTDGMHPSWVAKQKFKPKIAAFQGTKI
Protein: Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1) (GABAAR subunit alpha-1) (P62812)
Organism: Mus musculus (Mouse)
Function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity. GABRA1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection. Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
Subcellular location: Postsynaptic cell membrane {ECO:0000305|PubMed:16945976}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P14867}. Cell membrane {ECO:0000269|PubMed:16380713, ECO:0000269|PubMed:25422464, ECO:0000269|PubMed:25579817}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P14867}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P62813}. Note=Located at the plasma membrane of astrocytes (PubMed:25422464). Located in the somatic, proximal and distal dendritic regions of cerebellar Purkinje cells and in the molecular layer (PubMed:16945976). {ECO:0000269|PubMed:16945976, ECO:0000269|PubMed:25422464}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit gamma-2
- Gamma-aminobutyric acid receptor subunit beta-2
- Gamma-aminobutyric acid receptor subunit beta-3
- Gamma-aminobutyric acid receptor subunit beta-1
- Vesicle-fusing ATPase
- Huntingtin-associated protein 1
- Trafficking protein, kinesin binding 2
- Gamma-aminobutyric acid type B receptor subunit 2
- Inactive phospholipase C-like protein 1
- Gamma-aminobutyric acid type B receptor subunit 1
Sequence:
MKKSRGLSDYLWAWTLILSTLSGRSYGQPSQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
Protein: C2H2-type domain-containing protein (Q8BLE1)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MQHQRIHTGEKPYKCDECGKAFIRGSQLTQHQRVHTNEKPYECKECGKTFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYKCKECGKNFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCSECGKAFARGLLLIQHQRIHTGEKPYQCRECGKAFIRSSQLTQHQRTHTGEKPYECRECGKAFGHGSQLTLHQRVHTGEKPYECKECRKAFTQSSHLSRHQRVHTGEKQYQCKECEKAFTRESQLMRHQRIHIRGKSLDCKECRIDFNHHSQIFI
Protein: Chromatin-remodeling complex ATPase chain isw-1 (EC 3.6.4.-) (Nucleosome-remodeling factor subunit isw-1) (P41877)
Organism: Caenorhabditis elegans
Function: Energy-transducing component of a NURF-like (nucleosome-remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Probable histone-binding protein lin-53
- Bromodomain adjacent to zinc finger domain protein 1A
- DNA polymerase epsilon subunit 3
- Nucleosome-remodeling factor subunit NURF301-like
- ZP domain-containing protein
- histone acetyltransferase
- PHD-type domain-containing protein
- Suppressor of spindle checkpoint defect 1
- Malignant brain tumor repeat protein 1
- Pre-mRNA-splicing factor 38
Sequence:
MSVHESSNEINDEPMDTDSNIPESSGNDPSMEVDDEPESSDAADSFKRFERLLQKTENFSHCLSSGDAKLATGAPVDTKKRGRPSKKNGIDGDHRHRKTEQEEDEEMVADAIKSDDLVIFDKSPFYIENGEMRDYQVRGLNWLASLQHNKINGILADEMGLGKTLQTISMIGYMKHYKNKASPHLVIVPKSTLQNWANEFKKWCPSINAVVLIGDEAARNQVLRDVILPQKFDVCCTTYEMMLKVKTQLKKLNWRYIIIDEAHRIKNEKSKLSETVRELNSENRLLITGTPLQNNLHELWALLNFLLPDIFTSSDDFDSWFSNDAMSGNTDLVQRLHKVLQPFLLRRIKSDVEKSLLPKKEVKVYVGLSKMQREWYTKVLMKDIDIINGAGKVEKARLMNILMHLRKCVNHPYLFDGAEPGPPFTTDQHLVDNSGKMVVLDKLLMKFKEQGSRVLIFSQFSRMLDLLEDFCWWRHYEYCRLDGSTPHEDRSNAIEAYNAPDSKKFIFMLTTRAGGLGINLATADVVIIYDSDWNPQSDLQAMDRAHRIGQKKQVRVFRLITENTVDERIIEKAEAKLRLDNIVIQQGRMSEAQKTLGKGDMISMIRHGAEQVFAAKDSTISDDDIDTILEKAEVKTAELNEKMGKIDENNLRNMTFEDNAKFTVYQFEGENYKAKQADGMGHFWIEPPKRERKANYQVDLYYKEAMRAGNPTEKQSKAPRPKLPQVFDFQFYPRRLFELLDKEIYHYRKTIGYVAERPKDVPPKEAEKRQAEEQKLINNARPLTDKEQEEKAELLTQSVTDWTKREFQQFVRGNEKYGREDLESIAKEMERPLEEIQSYAKVFWERIEELQDSEKVLSQIEKGEARIQRKYAVKKALDAKIAKYKAPFQQLRISYGTNKGKTYTEEEDRFLVCETHRLGHDKENVFEELRQSVRMAPQFRFDWFLKSRTAMELQRRCNTLITLIEREMGEVVESKPVIVTAADKKKSVAKDLSKSSGTPTAKKVKATPK
Protein: Probable ketoamine kinase lp_1983 (EC 2.7.1.-) (F9UPU7)
Organism: Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum)
Function: Ketoamine kinase that phosphorylates ketoamines, such as erythruloselysine, erythrulosecadaverine, ribuloselysine and ribulosecadaverine, on the third carbon of the sugar moiety to generate ketoamine 3-phosphate. Has higher activity on free lysine (erythruloselysine and ribuloselysine), than on ribuloselysine and erythruloselysine residues on glycated proteins.
Interaction partners:
Sequence:
MHLTKTWLAQLPLTDIQQVQPVSGGDINAAFQIITRHHQYFLKVQPHNDVTFFDHEVAGLRLLGAVTKTPRVIASGTIATDGYLLLDWLATGTGSQSALGAAVAKVHHQHHAQFGLDHDFTAGKLPKINHWQTDWATFYTQQRLDVLVNLAKEHHLWSETREMHYHRLRQQLLQDSHMHTVKPSLLHGDLWSGNYLFDTTGTPVLIDPDVFYGDREMDLAMTTIFGGFDTDFYQAYQAAYPVAPGMQDRLPSYQLYYLLAHLNLFGETYGPAVDRILMQY
Protein: Beclin-1 (F6PQC7)
Organism: Macaca mulatta (Rhesus macaque)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU367123}. Golgi apparatus, trans-Golgi network membrane {ECO:0000256|ARBA:ARBA00004150, ECO:0000256|RuleBase:RU367123}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004150, ECO:0000256|RuleBase:RU367123}. Endosome membrane {ECO:0000256|ARBA:ARBA00004481, ECO:0000256|RuleBase:RU367123}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004481, ECO:0000256|RuleBase:RU367123}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004406, ECO:0000256|RuleBase:RU367123}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004406, ECO:0000256|RuleBase:RU367123}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004318, ECO:0000256|RuleBase:RU367123}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004318, ECO:0000256|RuleBase:RU367123}. Cytoplasmic vesicle, autophagosome {ECO:0000256|RuleBase:RU367123}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPASPSRPTFVLSVSVEDQHGLPLGERMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
Protein: Zinc finger protein 668 (Q96K58)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000269|PubMed:34313816}.
Interaction partners:
- Zinc finger and BTB domain-containing protein 45
Sequence:
MEVEAAEARSPAPGYKRSGRRYKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGEKVSGSAAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEGVKPYHCEKCGKDFRQPADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTHRSSEAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGEEADEKPPQFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTHPVPMGTPTPLEPLVALLGMPEEGPA
Protein: Microtubule-associated protein (A0A126GV16)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU000686}.
Interaction partners:
Sequence:
MADVLEKSSLLDAVPPLGDPHPPLPHQQLQQEAAAAAAANAAPPAPPQQQQPPPHQLQQQQPQQQQLQQKPANARANQDQKEGDNDSGVDESTQEKDRNGPNSPSSPVKTPTSTSSKPDKSGTSRPPSATPSNKSAPKSRSASKNRLLLKTPEPEPVKKVPMNKVQVGHAPSPNLKAVRSKIGSLDNATYKPGGGHVKIESKKIDIKAAPRIEAKNDKYMPKGGEKKIVTTKLQWNAKSKIGSLENAAHKPGGGDKKIETLKMDFKDKAKPKVGSTANVKHQPGGGDIKIQTQKLEIKAQSKVGSLDNVKHKPGGGEKKIFDDKDYLKNVEHSVALTTPPTQFALQGRLIATIHLEFGLCNSDCVCNNIFESLFK
Protein: Probable disease resistance protein At5g66900 (Q9FKZ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable disease resistance protein.
Interaction partners:
- Probable disease resistance protein At5g45490
- Disease resistance protein
- Probable disease resistance protein At4g14610
- PTI1-like tyrosine-protein kinase At3g15890
- Powdery mildew resistance protein, RPW8 domain-containing protein
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Disease resistance protein
- At3g04210/T6K12_17)
- Probable LRR receptor-like serine/threonine-protein kinase At1g51860
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
Sequence:
MNDWASLGIGSIGEAVFSKLLKVVIDEAKKFKAFKPLSKDLVSTMEILFPLTQKIDSMQKELDFGVKELKELRDTIERADVAVRKFPRVKWYEKSKYTRKIERINKDMLKFCQIDLQLLQHRNQLTLLGLTGNLVNSVDGLSKRMDLLSVPAPVFRDLCSVPKLDKVIVGLDWPLGELKKRLLDDSVVTLVVSAPPGCGKTTLVSRLCDDPDIKGKFKHIFFNVVSNTPNFRVIVQNLLQHNGYNALTFENDSQAEVGLRKLLEELKENGPILLVLDDVWRGADSFLQKFQIKLPNYKILVTSRFDFPSFDSNYRLKPLEDDDARALLIHWASRPCNTSPDEYEDLLQKILKRCNGFPIVIEVVGVSLKGRSLNTWKGQVESWSEGEKILGKPYPTVLECLQPSFDALDPNLKECFLDMGSFLEDQKIRASVIIDMWVELYGKGSSILYMYLEDLASQNLLKLVPLGTNEHEDGFYNDFLVTQHDILRELAICQSEFKENLERKRLNLEILENTFPDWCLNTINASLLSISTDDLFSSKWLEMDCPNVEALVLNLSSSDYALPSFISGMKKLKVLTITNHGFYPARLSNFSCLSSLPNLKRIRLEKVSITLLDIPQLQLSSLKKLSLVMCSFGEVFYDTEDIVVSNALSKLQEIDIDYCYDLDELPYWISEIVSLKTLSITNCNKLSQLPEAIGNLSRLEVLRLCSSMNLSELPEATEGLSNLRFLDISHCLGLRKLPQEIGKLQNLKKISMRKCSGCELPESVTNLENLEVKCDEETGLLWERLKPKMRNLRVQEEEIEHNLNLLQMF
Protein: Alpha-amylase/trypsin inhibitor RA16 (Allergen RA16) (allergen Ory s aA_TI) (Q8H4L8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Seed storage protein.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MASNKVVISALLVVVVSVLAATTTMADHHQEQVVYTPGQLCQPGIGYPTYPLPRCRAFVKRQCVAPGTVDEQVRRGCCRQLAAIDSSWCRCDALNHMLRIIYRESGAADAGHPMAEVFRGCRRGDIERAAASLPAFCNVDIPNGVGGVCYWLPGTGY
Protein: 5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (EC 2.7.11.26) (EC 2.7.11.31) (Acetyl-CoA carboxylase kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (Tau-protein kinase PRKAA1) (A0A060YAF5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- AMP-activated protein kinase glycogen-binding domain-containing protein
- 5'-AMP-activated protein kinase subunit beta-1
- Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
- CBS domain-containing protein
- CBS domain-containing protein
- 5'-AMP-activated protein kinase subunit gamma-1
- 5'-AMP-activated protein kinase subunit gamma-1
- Association with the SNF1 complex
- Association with the SNF1 complex
- calcium/calmodulin-dependent protein kinase
Sequence:
LPLSLSCPLSLSLLPVPPSIHELTKHQVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQIISAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFFTPQYLNPSVAALLKHMLQVDPMKRATIKEIREDEWFKEELPKYLFPEDPSYSNNMIDDEALKEVCEKFECTEEEILTCLYSRNHHDPLAVAYHLIIDNRRIMSEAKDFYLASSPPDSFLDDQHLTASAAAAAGLKPHPERMQPFLAVETPPRPRHTLDELNPQKSKHQGVRRAKWHLGIRSQSRPNDIMSEVCRAMKQLDYEWKVVNPYYLRVKRKSPVTGMQTKMSLQLYQVDSRTYLLDFRSIDNDMLEAKSGTATPHRSGSVGNYRTALKNDTAEEGGSQTEEAKDDATLTPATSIPPTPTKASESSLASSLTSSVDSTGGDLAPTTVYPRPGSHTIEFFEMCANLIKLLAR
Protein: Neurogenic differentiation factor 1 (NeuroD) (NeuroD1) (P79765)
Organism: Gallus gallus (Chicken)
Function: Acts as a transcriptional activator that mediates transcriptional activation by binding to E box-containing promoter (5'-CANNTG-3'). Acts as a differentiation factor during neurogenesis. Induces photoreceptor cell overproduction in vivo and de novo generation in vitro. May play a role in photoreceptor cell production.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Paired box protein Pax-6
- Insulin gene enhancer protein ISL-1
- Myelin transcription factor 1 like.
- Regulatory factor X6.
- Transcription factor SOX-2
- POU domain, class 4, transcription factor 1
- LIM/homeobox protein Lhx3
- Forkhead box N4
- Glial fibrillary acidic protein
- Nescient helix-loop-helix 1
Sequence:
MTKSYSESGPAGEPQAQAPPGWAAGCLSPPADGPEADKKEEDLEALHGEAEEDALRNGEEEDEEDELDEEEEEEEEEEDDEQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRTFLPEQSADAAPHLPPAGAPFAPPPFPYASPGLPSPPYGTMDSSHLFHLKPPHAYGAALEPFFEGGLPEGAGPAFDGPLSPPLSINGNFSFKHEPAADFDKSYAFTMHYPAGPLPAAPAHAAVFSGAAARCELPGDGLAPYEGHPHHERVLSAQLSAIFHE
Protein: Protein lifeguard 3 (Responsive to centrifugal force and shear stress gene 1 protein) (Protein RECS1) (Transmembrane BAX inhibitor motif-containing protein 1) (Q8BJZ3)
Organism: Mus musculus (Mouse)
Function: Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000250}. Endosome membrane {ECO:0000250}.
Interaction partners:
- Growth hormone-inducible transmembrane protein
Sequence:
MSNPSAPPPYEDHNPLYPGSPPPGGYGQPSVLPGGYPAYPAYPQPGYGHPAGYPQPVPPVHPMPMNYGHDYNEEERAGSDSFRPGEWDDRKVRHSFIQKVYCIISVQLLITVAIIAIFTFVEPVGKYVRNNVAVYYVSYAVFLVTYLTLACCQGPRRRFPWDIILLTIFTLALGFVTGTISSMYENKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLMVTGIVTSIVLIFKYIYWLHMVYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIVYIFTFVLQLVGSRD
Protein: Protein OPG200 (P24772)
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Function: Contributes to virulence by binding to the host IKBKB subunit of the IKK complex and preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B. Mechanistically, sterically hinders the direct contact between the kinase domains of IKBKB in the IKK complex containing IKBKB, CHUK/IKKA and NEMO.
Interaction partners:
Sequence:
MTANFSTHVFSPQHCGCDRLTSIDDVRQCLTEYIYWSSYAYRNRQCAGQLYSTLLSFRDDAELVFIDIRELVKNMPWDDVKDCAEIIRCYIPDEQKTIREISAIIGLCAYAATYWGGEDHPTSNSLNALFVMLEMLNYVDYNIIFRRMN
Protein: Fatty acyl CoA synthetase 4 (EC 6.2.1.3) (Q38FB7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Monoglyceride lipase, putative
- Monoglyceride lipase, putative
- Lipase-like protein, putative
- Fungal lipase-type domain-containing protein
- Long-chain-fatty acid-CoA ligase protein, putative
Sequence:
MGGCVISVMDYMNNRSEVENEHVKKFRALGKVAVPVPGSETSDCSPIYRLVTDDGKDIEEVRREWYEGECLPQRFAALCKRQPKQRALAYRPVDRVEKAVIKDLHTGTEKMMNVTHFKETKYLDYGTFWDYIESFGRGLVELGISPSSRVAIYEETRWEWLATIYGIWSQNMVATTVYANLGEDALAYALRETGCKGIICNAKNVSVVIKFMSEGITPSAPIIYNGSLPASVDQEACHLVSWEEVVKLGREARDRLPLNNSGRADDLALIMYTSGTTGDPKGVIHTHGSLMSGVHALDHRLNAVMGPLRDGETYLSYLPLAHILELGVLSVFIARGALICFGSPFTLTDLTARPRGDLAEYNPSLLIGVPRIYDTLKKAIQAKLPAPGTFKRRAFDHAFQSRLRAFKDGKDSPYWDAKVFAATRAVLGKNMYMVLSGGGPLSTATQDFLNVAVVRIIQGWGLTETVCVGGVQLTGDIETGAVGPPLLSEEVKLLDVEGYKHTDEPDPRGEILLRGPFLFKGYYKQEELTKEAIDEDGWFHTGDVGSIGPNGTLRIIGRVKALAKNVLGEYVAMETLESMYAHNSLSMPNGVCVLVHPDRPYICALVLTDEAKVVAFTREHGLKGKYPEVLQDPEFQKKATASFQETARASDRQKFEIVRHVRLLSDEWTPENGVLTAAGKLKRRVIDEKYTDTIVSLFVEEC
Protein: Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (L-3-phosphoserine phosphatase) (O-phosphoserine phosphohydrolase) (P78330)
Organism: Homo sapiens (Human)
Function: Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine (Probable).
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:1965857}.
Interaction partners:
- Phosphoserine aminotransferase
- Serine hydroxymethyltransferase, cytosolic
- Serine hydroxymethyltransferase, mitochondrial
- Alanine--glyoxylate aminotransferase
- Cystathionine beta-synthase-like protein
- L-serine dehydratase/L-threonine deaminase
- Serine racemase
- D-3-phosphoglycerate dehydrogenase
- Serine dehydratase-like
- Threonine synthase-like 1
Sequence:
MVSHSELRKLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKAALTERLALIQPSREQVQRLIAEQPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVASKLNIPATNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIKLLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELEE