wanglab/gogpt-training-data huggingface dataset:
Protein: Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog) (O60287)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:16963496}.
Interaction partners:
- Protein RRP5 homolog
- Small subunit processome component 20 homolog
- HEAT repeat-containing protein 1
- DNA-directed RNA polymerase I subunit RPA1
- RNA cytidine acetyltransferase
- Unhealthy ribosome biogenesis protein 2 homolog
- WD repeat-containing protein 36
- Nucleolar protein 8
- Transducin beta-like protein 3
- U3 small nucleolar RNA-associated protein 4 homolog
Sequence:
MGVPKRKASGGQDGAASSAGAAKRARKEELTGVRFKAQLKDPQGPGPGLEAFVSAAKKLPREDVYDVVEGYIKISVECVEIFQLLSGEKRPESETMLIFQVFEAILLRTASDLSHFHVVGTNIVKKLMNNHMKLICESLYASGYRLARACLSLMTAMVTQGPEAARDVCSHFDLNKKTLYTLVTKRDSKGVYDVRQAYVQFALSFLIAGDDSTIVQVLEVKEFIPCIFSSGIKEDRISTINILLSTLKTKVVHNKNITKTQKVRFFTGQLLNHIASLYNWNGITDVNPENVKVSAEEAGKTMVRELVHNFLMDLCCSLKHGINFYDASLGTFGRGGNLTLLHFLLGLKTAADDDLVADLVVNILKVCPDLLNKYFKEVTFSFIPRAKSTWLNNIKLLNKIYEAQPEISRAFQTREFIPLPRLLAMVMVTTVPLVCNKSMFTQALNLDSTSVRHTALSLISVILKRALKTVDHCLNKEVWQESGVYTAVMMEEFVQLFREALSKILPDLNTVVWVWQSLKKQETKQDDKKGQKRSDGPPAACDAHQCDDAETILLKAVLLQVICLYQKVVPHVVMQYNFDFSKLLKGVISEQGLREEVPPILQHHMLKVALELPASKFLWLKAQEGPDAEIIGGERSVFYLLMKMFVTSSHLQLKSLTKLLIMKILRDTGVFEHTWKELELWLEHLENTMEEDKETVIQFLERILLTLVANPYSYTDKASDFVQEASMLQATMTKQEADDMSIPISHIDDVLDMVDVLVEGSEGLDEEIGFTLSEDMILLTFPFSAVVPAALEARNKLLLGTGNEAAENVVTYLTAVLTDLLHTQRDPLALCLLLQAYDKLEPPCLVPCCQQLSRFNRYYSLWIPEQAREAWLLQAQGSPSPPALPLASSFTALLQAAYESQALRDEHIQVQLQATMPHLSMQQVLLAAKQVLLYLRSTVENFGQLGRSVGPPLLQLFLDLLRRLVVHCEQLDAQNQQRCEAARAEADLFLDMESVASLELANDQTLEEVLVAILRHPTLEGWFLALEQQALPPHTLSPVLVKLLATHFSAGVLQLLAASAPILQNIGQLGLLARYSEAITQSVLKELQNRRAGPATSPPKTPPQLEALQELHPYMEGAQLREVTLALLSLPETHLVTQQPTKSPGKERHLNALGKTLVQLLTCSPQDQLQSGELLWSSEYVRGLGALLPTLAVDELDTVLLHTLQRDPVLAPAVGADLLDYCLARRTQAALSIAALLLQESCTHLLWFEQWCLQAGPGLGLQGDLDDFLPLIHVYLQCRTRSHFTRPAGVSSAVIPVLRKTLWRQLQSRLLSTDSPPASGLYQEILAQLVPFARAKDLSVLMDRLPSLLHTPSSHKRWIVADSISAALEGSAEELCAWRRTLLESCVKWLIVSFSGGQQDDDNTQNQEKEMLLRLNALLHALNEVDPGDWQKFVKKGLKFRYQDHTFLKMLLTAVQLLYSPESSVRTKLIQLPVVYVMLMQHSLFLPTLLTSDGEESPDSQVKEALVDLMLTVVEMCPSVCESSHFAVLLGAYGATLSVLDQKILLLLRAYEQNKLSLINFRVLLWGPAAVEHHKTCRSLGRSLWQQPSVGDILRLLDRDRMMQTILHFPQNRRLLPPEDTQELIFKDKSRVDLDGLYDPCFLLQLFSELTRPEFVVDCRKFLDSNALGLTVTALSSYDPQMRAIAYHVLAAYYSHLEGARFQEQSQLLYLLDVVRNGIRTQDMRLTFTLALFIAKAALQILKPEEHMYLKVSNFLLSHEYLNMDKVPGFYQFFYSSDFEQKTEQKWVFGVLRQGIRDKQCYELCARRGIFHIILSFFHSPLCDEAAQNWILEILQNAAQVARSAYEIIRDYSLLTWILHILESKFLETPLLSNVISLLHTLWVTNLGDKAVEWESQRLCQPSSQEPAKRLALHLVNEFLYVLIVLMKHLRPTLAPVQLTNFFGTLDSVLRYRATVIQAFRDMNRFTVNETVLSTKDVLVLLHKWSLIERDLKLQEDLRAAIEKAQARELMKMLKDKNKPVMPARAKGPRGRKRRPGEAEEMADPELMASTLETCKGLLRSILTYWRPVIPGPDPTQEPVDSASPESDAPGPVYAAASLAVSWVLRSVAEHPLSRAEAAGLIGWLKSHILPHPVVVADLLKDSAVRSSIFRLYSRLCGAEGLAGPVQEVACLFNTVMLQLVAAQGRAGSPFHPAMEALSLSSLSEKDEATQASAAFLVSLYIKDIWLGAQRPDTLLTHVRMVCEAADDAPSSEEEAIVVLCKDAASAASDA
Protein: Pentatricopeptide repeat-containing protein At3g15590, mitochondrial (Q9LRP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305|PubMed:25732537}.
Interaction partners:
Sequence:
MYSLSRILQRSQRYNFAPSSFGAVSKLEVSSGGDKERVFKSFGLIYSKPQGLVRLYSARDVFSRFFGIHKLSSIADAKDKGDEVVREEELSESEEAVPVSGDVPEGVVDDDSLFEPELGSDNDDLEIEEKHSKDGGKPTKKRGQSELYESIVAYKSVKHVLEKWVKEGKDLSQAEVTLAIHNLRKRKSYAMCLQLWEWLGANTQFEFTEANYASQLDLVAKVHSLQKAEIFLKDIPESSRGEVVYRTLLANCVLKHHVNKAEDIFNKMKELKFPTSVFACNQLLLLYSMHDRKKISDVLLLMERENIKPSRATYHFLINSKGLAGDITGMEKIVETIKEEGIELDPELQSILAKYYIRAGLKERAQDLMKEIEGKGLQQTPWVCRSLLPLYADIGDSDNVRRLSRFVDQNPRYDNCISAIKAWGKLKEVEEAEAVFERLVEKYKIFPMMPYFALMEIYTENKMLAKGRDLVKRMGNAGIAIGPSTWHALVKLYIKAGEVGKAELILNRATKDNKMRPMFTTYMAILEEYAKRGDVHNTEKVFMKMKRASYAAQLMQYETVLLAYINAKTPAYGMIERMKADNVFPNKSLAAKLAQVNPFKKCPVSVLLDI
Protein: Cabin1 protein (Q80X22)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
ATVITCPPSASASIPDLSTDPGIPRPHRPETTPSRAPLSPEGEEASGVTEGTSILPQEPRYSHQIKMAATGHLAEQHCWPVEVACQTGAEPTCSQASSTKVPSSGSTQTAESHQGKTESSRAKSRLLPNMPKLVIPSATTKSPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV
Protein: Nonribosomal peptide synthetase 5 (EC 6.3.2.-) (Q4WYG2)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Nonribosomal peptide synthesis (NRPS) is a key mechanism responsible for the biosynthesis of bioactive metabolites which are potentially contributing to organismal virulence.
Interaction partners:
Sequence:
MNLTLTTTSITIQPSATMANRAPTLLDHFHDQLQKHSSSVAIEDGTQSADQGAWERVTYAQLDALSDSWSKRLRQAGVGAGCIVPLLSKRSVAMVAATLAILKLRAAYVSIDIDSWGKDRIDTVLKTVNPQIIVSTSPCPKDHYPYPVVALERNDFDETVTSNGTQWTRNDEDSIDRGNDLAYIIFTSGTTGIPKGVKIGQRSISRYVKEGGDLPFNFNTTHGTRVLLICSIAFDVCAGVMFNTLCNGGTLVLADPSTFETAAKTCHVLPLTPSILVTLDPKAGFDTVEKIFLGGESPSPSLIEAWSSPRRRLYNAYGPTETTCTAFMGELLPGSPITIGYPISYSTVTLLDEDGMESVEGEICIAGLGLALGYFHDPERTNSAFVEWNGVRIYKTGDYGRRTKHGLQFCGRRDSVVKNRGFLINLEADVEPALLSYDKVDSASAFMSQGQLIAFVTPTSAKEGLREYLANTVSSFLVPDTIYSLDEFPRTSNGKVDRRSLMRMHELEQGSDTASLERGLGAVESVRRGLSHVLRLPESQILPASSFRHLGGHSLAAVMLVSVLRRMGFGISVAEVLLLDTVENIAAAVVELSDIPHALSAQEDLIERLRHDISTTRPLDEGVTIAPMTDMQTRLLGASVATPGLSFIKTSFTLDHPEKEDLTSTLRAAWVRLHQTHEILRTAFVLTASNGTQIISQEPDFSWKEKFVTESEWESVCRREEHLDVADFPDFDAENRASLSRVVLIIAPRRRTRFVWTVHHSLIDGWSMATLMRDFASCLDGKPIPAPPQFAQVAQAIGQLKAESSDRAVSFWKEYLDGYTPAQRLRVSPPSDVSDYTQAALSRKLTVSVSALEDAARDRFAVTPATLLYAAWGLLLSRYSGTDRAALGAVLSGRSLPIPGVENIIGPLINTLPLAINTQEAQSTYSFVQSVFRRLCDILEFQWSPVALIQEGCGCNPSELFETLFALQYDFPQTPWKSSEVPEPRDIRYEEATQVPLTVLLDNANGQFEVRFIYRRSHFGDATVQRMIGQFGNLLENLIAAQPDTDLSNVTGQMFNNRVYEMSIAKPGQPVSACKVPESLTEAIENSIQAHPDIYAVEGLTGRLTYREFGRMTEHISQRLLQHIQPGSVACMISDGSLLWLLAMVAIIRAGAIYCPVDEKLPRDRKDYMVRNSRAALILYANSSQEPLCNGVPSLNMESIMQEISSSSGSPIATSRNRPSGDTVACLVYTSGSTGLPKAVQLQHKGILNVISQPEGRLYSRPGQRNAQMLSLGFDCCIKEVFSTICFGATLVLKDPENPISHLARVDATMATPSLLATLEPTDYPNLKVITVAGEAVSQVLNDKWAAGRTLINGYGPAECTLISTTAILHPGNRVSIGKPLPGLSCYLLDSNKRPVPMGVSGEIYISGVQVTPGYLHNEQETSKRFLSDSFNPGQVMYRTGDIGRMLEDGNIEYIGREDNQIKLRGFRIDLGEVQSTISKLASTASNVALIVSNGNLVAFMTPETIDVRSLAKSLETQLPQYAVPNRIIALATLPTSANNKVDSSALQRYLRDHGKDGAVVEDLETDTQRVLAVIWADMLGRDLNQTPISPSDRFFELGGHSLLQIKVAQAISKRWNIRPLPLKQVIRHHSLQDLSLAIDELVSDPRTVSTMPFLEMTPVARNGQLPLSYLEKEMLLNHLISGGSPAGNMNFVCKIRGDINAETLADAFQRVTADVEVFRTRYSVIEGTLFRQQAPGSVKVPRVVQTGNLSSFVHGRITKSFDLSTEPPVDVSIIIGTPMQAMLVVVMSHVVGDAATMATYLNRVSRTYDLLRSNSQTTNTSTVPDNLTYIDWAHWASTLQPNPRALTFWSSYLSNPPSPLTFGNPSPAPATYIGLTRSWTLPPSMYRKLSDLAAKASVTMHQLILAAVFFSLQCVDRRDDILVAAPFTHRTEPGTESLPGLFLDRLLLRIQRSPHQSSIFDFLSSVRETSQQALAHVIPFHTLRHSLAHKPSLIDPLFKVMVTYHTAADQRPLLDLSGAEVQPIPWRHTGGSKFPLKFEFTEMATQDLEVDMEYDLGCIREDIALRLEFALSFALQLMVLERETDDIIQLVQMSFCPGEGSPVGLTPSHEGSAELTNGTNKTDSTTGQQELENNLTDVVCECLGLEIQDVDADKSFWDLGAQSMDALKLQHLCEKRGVRVRLRDIFVSRSLLELATCAVII
Protein: Modular serine protease (EC 3.4.21.-) [Cleaved into: Modular serine protease non-catalytic chain; Modular serine protease catalytic chain] (Q9VER6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Serine protease that plays a key role in innate immunity by activating the Toll pathway in response to infection with Gram-positive bacteria and fungi. During Gram-positive infection, acts downstream of PGRP-SA and upstream of Grass and Spz, and therefore appears to function in a pathway that links detection of Gram-positive lysine-type peptidoglycans to Toll activation. Functions in a separate pathway to the psh-mediated activation of the Toll pathway.
Subcellular location: Secreted {ECO:0000269|PubMed:19590012}. Note=Localizes at the membrane of lipid vesicles. Secreted from the fat body into the hemolymph at the surface of these lipid vesicles. {ECO:0000269|PubMed:19590012}.
Interaction partners:
- Gram-negative bacteria-binding protein 3
- Gram-negative bacteria-binding protein 1
- Peptidoglycan-recognition protein SA
- Serine protease grass
- Peptidoglycan-recognition protein SC1a
- Peptidoglycan-recognition protein SC2
- Spaetzle-processing enzyme
- Protein spaetzle
- Sphinx1
- trypsin
Sequence:
MQLISFLSNPLFFCALLLKFRTIFAACDSSQFECDNGSCISQYDVCNGEKNCPDGSDETALTCVSQRQHCTKPYFQCTYGACVIGTAGCNGVNECADGSDETRLRCGNEDDIRQHDRRLQGNCKENEFKCPSGICLDKSNFLCDGKDDCADGTGFDESVELCGHMECPAYSFKCGTGGCISGSLSCNGENDCYDGSDEAPLLCNTTKKVTTPVVTETPLELLGCPLPLGDERPILTGDGSRVLTGPITRGTVRFSCKQGYVLEGEESSYCAKNKWSTSTIPKCVKYCSTAGEFDGYSTKALCTHNGQQVECRKPFHPPGTEVKFVCSTGFKTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNIENKHELQFVPAVSKSNSVCRRNLRDIQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQCAHSLTVMTNIQHFEDMILNAMNRSVETRS
Protein: P-loop containing nucleoside triphosphate hydrolases superfamily protein (Putative 26S proteosome regulatory subunit) (Q0WVF7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000256|ARBA:ARBA00004436}.
Interaction partners:
Sequence:
MAQKCAIGLISALAASASLAKSKVASADGPFNLSGFSTSANPQQQASPPPPSLAGEESSAPPRARNDNPRTSSGGFDPEALERGAKALKEINHSSYAKKVFESIKQQEETKQTEFATKAQEFKAMQAQAETERHKVIYDEQKKLAQHQAQTKSQMARYEDDLARKRMQAENEFHRTRNQELVKMQEDSAIRQEQARRATEEQIQAQRRQTEREKAEIERETIRVKAIAEAEGRAHEARLAEDVNRRMLVDRANAEREKWVAAINTTFDHIGGGLRAILTDQNKLIVAVGGVTALAAGIYTTREGAKVIWSYVDRILGQPSLIRESSRGKYPWSGSLSRVMSTLRGKESASKNGKRFGDVILHPPLAKRIEHLATSTANTKLHQAPFRNILLHGPPGTGKTMAARELARKSGLDYALMTGGDVAPLGAQAVTKIHELFDWGKKSKRGLLLFIDEADAFLCERNKTYMSEAQRSALNALLFRTGDQSKDIVLALATNRPGDLDSAVADRVDEVLEFPLPGEEERFKLLNLYLEKYIAEAGPSKPGLFDRLFKKEQQKIEIKGVTEELLKEAAAKTEGFSGREIAKLMASVQAAVYGSEDCVLDSMLFREVVDYKVAEHQQRRKLAGVDSK
Protein: Alkylated DNA repair protein ALKBH6 homolog (EC 1.14.11.-) (Alpha-ketoglutarate-dependent dioxygenase B homolog 6) (AtALKBH6) (Protein ALKB HOMOLOG 6) (Q9SUP1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000269|PubMed:32933187}.
Interaction partners:
- YTH domain-containing protein ECT4
- YTH domain-containing protein ECT3
- RNA demethylase ALKBH9B
- RNA demethylase ALKBH10B
Sequence:
MELERFRVGLTPTVFYIPGFITDEEQTQLLNHIYGASGSKWKTLKNRRLQNWGGMVHEKGLVPQELPPWLTKITAEIHESSGLFPSAINHVLINEYHPDQGIMPHQDGPAYFPVVAILSLGSPVVMDFTPHLRLRSGDGYISKDQSPCAESCAPERDSFSVLLMPQSLLIFKDDAYSDFLHGISDSPTQCYNQVVNEAEALAYSNEEDSRKDGDKIFHRDQTRVSLTCRLVPKVRKNLFRF
Protein: Ceramide-1-phosphate transfer protein (CPTP) (Glycolipid transfer protein domain-containing protein 1) (Q8BS40)
Organism: Mus musculus (Mouse)
Function: Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. Has no activity with galactosylceramide, lactosylceramide, sphingomyelin, phosphatidylcholine, phosphatidic acid and ceramide. C1P transfer is stimulated by phosphatidylserine in C1P source vesicles (By similarity). Regulates autophagy, inflammasome mediated IL1B and IL18 processing, and pyroptosis, but not apoptosis.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q5TA50}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q5TA50}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q5TA50}. Cell membrane {ECO:0000250|UniProtKB:Q5TA50}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q5TA50}; Cytoplasmic side {ECO:0000250|UniProtKB:Q5TA50}. Endosome membrane {ECO:0000250|UniProtKB:Q5TA50}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q5TA50}. Nucleus outer membrane {ECO:0000250|UniProtKB:Q5TA50}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q5TA50}.
Interaction partners:
Sequence:
MDDSEKDFNLKVVLVSFKQCLTDKGEVLLDHYIAGWKGLVRFLNSLGAVFSFISKDVVAKLQIMERLRSSPQSEHYASLQSMVAYEVSNKLVDMDHRSHPRHPHSGCRTVLRLHRALHWLQLFLDGLRTSSEDARTSTLCSEAYNATLANYHSWIVRQAVTVAFCALPSRKVFLEAMNMESTEQAVEMLGEALPFIEHVYDISQKLYAEHSLLDLP
Protein: Contig An03c0120, genomic contig (EC 1.10.3.-) (A2QGL7)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Interaction partners:
Sequence:
MKWSHPNALVLPVLSWLVQSSSSRIVDFRLDLTWEDSNVAGISRKAIHTNGQVPAPNIRVNQGDQVRVLVNNSMPFGTTVHWHGIAQYGTPWSDGVPGLNQEMIKPGEQYKYEWTATDYGSYAYHAHTRAQMDDGLYGAIYVEPRSDVQRPFSKISTVPYELQAMLQAEKNTHPIMLSDWRAFTSEETLQIEEDSGVQATCANAILINGKGAVICPPQDHINALTRSGERTALGNKTMSDMGCMPPLAARLGGFPFDETKIPSGYYQGCVPTDGEQEVLSVDPRSRYVSYDLISLPGTSNLVFSIDEHPMYLYAVDGRYVEPLVVDAINVYAGARYSVLVKLDQPVSIYTVRVANKFANQIINGTAIMSYTGSQPSQFNTSAPYINEVGTALGFNGTIILDEADIVPFENEAPAPEPDQTQILNVKLYNASYRWTLGQASYPMSNEDLTPPALFNYSSIPSEYTVMTKNNTWVDLIFNMSTIGQPQHPIHKHSNKFYVLGWGYGVWKWSTVAEAQKDIPDSFNLVNPQLRDTFQTPASTPNHSWLAIRYHSVNPGPFFIHCHLSMHESGGLAVALLDGVDAWPTVPDRYQLPALADPEENTPTTHGLMDHPSFD
Protein: 4-chlorobenzoate--CoA ligase (4-CBA:CoA ligase) (EC 6.2.1.33) (A5JTM6)
Organism: Pseudomonas sp. (strain CBS-3)
Function: Catalyzes the formation of chlorobenzoyl-CoA via a 2 step reaction. First 4-chlorobenzoyl is adenylated by ATP, followed by acyl transfer from the 4-chlorobenzoyl-AMP intermediate to CoA. Benzoate, 4-bromobenzoate, 4-iodobenzoate and 4-methylbenzoate also act as substrates. Inactive towards 4-aminobenzoate, 4-hydroxybenzoate, 2-aminobenzoate, 2,3-dihydroxybenzoate, 4-coumarate and the aliphatic carboxylic acids palmate, caproate, laurate and butyrate. Negligible activity is detected when ATP is replaced by UTP, CTP or GTP as cosubstrate.
Interaction partners:
Sequence:
MQTVHEMLRRAVSRVPHRWAIVDAARSTFDICRTGETSRNEGSATARLWPQPARPLAVVSGNSVEAVIAVLALHRLQAVPALMNPRLKPAEISELVARGEMARAVVANDAGVMEAIRTRVPSVCVLALDDLVSGSRVPEVAGKSLPPPPCEPEQAGFVFYTSGTTGLPKGAVIPQRAAESRVLFMATQAGLRHGSHNVVLGLMPLYHTIGFFAVLVAAMAFDGTYVVVEEFDAGNVLKLIERERVTAMFATPTHLDALTTAVEQAGARLESLEHVTFAGATMPDTVLERVNRFIPGEKVNIYGTTEAMNSLYMRAVRIAGTVMRPGFFSEVRIVRVGGDVDDGCPTVKRASWRWRRRMRPFQATLTNLRLLQKSFRKAGTGRAICVRDGSGNIVVLGRVDDMIISGGENIHPSEVERILAAAPGVAEVVVIGVKDERWGQSVVACVVLQPGASASAERLDAFCRASALADFKRPRRYVFLDELPKSAMNKVLRRQLMQHVSATSSAAVVPAPAVKQRTYAPSGRAIAR
Protein: Histone acetyltransferase GCN5 (EC 2.3.1.48) (Q59PZ5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Histone acetyltransferase
- Transcriptional adapter 2
- Histone acetyltransferase
- Transcription initiation factor TFIID subunit 10
- SGF29 C-terminal domain-containing protein
- Protein SPT3
- Ubiquitin carboxyl-terminal hydrolase
- Histone H4
- SAGA histone acetyltransferase complex subunit
- Deubiquitination module subunit
Sequence:
MVDRKRTAAIRAEDDDEENDNVPLQKKVKIEAKQKEEEEDGDKSGATETKSEVKQESKEETTQKENNEEDEEEEEEEDDEEAEEEKKRITNFNFDGEIYTFKERPSVIEEKEGKIEFRVVNNDNSRENLIVLTGLKNIFQKQLPKMPREYISRLVYDRSHLSMAVVRKPLTVVGGITYRPFNNRGFAEIVFCAISSTEQVRGYGAHLMNHLKDYVRATSPIKYFLTYADNYAIGYFKKQGFTKEISLDKSVWMGYIKDYEGGTLMQCSMLPSILRYLDSGKILLLQKAAIERKIRSRSKSKIVRPGLQVFKTNKNVTLDPKDIPGLAEAGWSEEMDKLAQKPKRGPHYNFMVTLFSEIQNHPSAWPFAVAVNKEEVPDYYRVIEHPIDLATIEQKLENNLYLKFTDFVDDLKLMFNNCRAYNSETTTYYKNANKLEKFMNNKLKDCSFV
Protein: Allatostatin C, isoform B (Allatostatin preprohormone) (Q95NV8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMKFVQILLCYGLLLTLFFALSEARPSGAETGPDSDGLDGQDAEDVRGAYGGGYDMPAQAIYPNIPMDRLQMLFAQYRPTYSAYLRSPTYGNVNELYRLPESKRQVRYRQCYFNPISCFRK
Protein: L-cysteine S-thiosulfotransferase subunit SoxA (EC 2.8.5.2) (Cytochrome c551 subunit monoheme) (Protein SoxA) (SoxAX cytochrome complex subunit A) (Sulfur oxidizing protein A) (Thiosulfate-oxidizing multienzyme system protein SoxA) (TOMES protein SoxA) (D7A6E5)
Organism: Ancylobacter novellus (strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIMB 10456) (Starkeya novella)
Function: C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c that then channels them into the respiratory electron transport chain. Some electrons may be used for reductive CO(2) fixation.
Subcellular location: Periplasm {ECO:0000269|PubMed:15848194, ECO:0000269|PubMed:18552405}.
Interaction partners:
- Cytochrome c domain-containing protein
- Oxidoreductase molybdopterin binding protein
- 5'-Nucleotidase domain protein
- SoxAX cytochrome complex subunit A
- Uncharacterized protein
- Putative cytochrome c, putative SoxX protein
- Uncharacterized protein
- 3-mercaptopyruvate sulfurtransferase
- Sulfur oxidation protein SoxY
- Sulfur oxidation protein SoxZ
Sequence:
MRRFAAGCLALALLVLPFVLTGARAAEDESEKEIERYRQMIEDPMANPGFLNVDRGEVLWSEPRGTRNVSLETCDLGEGPGKLEGAYAHLPRYFADTGKVMDLEQRLLWCMETIQGRDTKPLVAKPFSGPGRTSDMEDLVAFIANKSDGVKIKVALATPQEKEMYAIGEALFFRRSSINDFSCSTCHGAAGKRIRLQALPQLDVPGKDAQLTMATWPTYRVSQSALRTMQHRMWDCYRQMRMPAPDYASEAVTALTLYLTKQAEGGELKVPSIKR
Protein: Linalool dehydratase/isomerase (EC 4.2.1.127) (EC 5.4.4.4) (Geraniol isomerase) (Linalool dehydratase-isomerase) (Myrcene hydratase) (E1XUJ2)
Organism: Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen) (Alcaligenes defragrans)
Function: Anaerobically catalyzes the stereospecific hydration of beta-myrcene to (3S)-linalool and the isomerization of (3S)-linalool to geraniol. Is thus involved in the initial steps of the anaerobic degradation of the monoterpene beta-myrcene. Also catalyzes the reverse reactions, i.e. the isomerization of geraniol to linalool and the dehydration of linalool to myrcene. In this direction, the formation of myrcene from geraniol may be seen as a detoxification process for the monoterpene alcohol. Neither the monoterpenes alpha- and beta-ocimene nor the monoterpenoids citronellol and nerol can be used as substrates.
Subcellular location: Periplasm {ECO:0000305|PubMed:20663876}.
Interaction partners:
Sequence:
MRFTLKTTAIVSAAALLAGFGPPPRAAELPPGRLATTEDYFAQQAKQAVTPDVMAQLAYMNYIDFISPFYSRGCSFEAWELKHTPQRVIKYSIAFYAYGLASVALIDPKLRALAGHDLDIAVSKMKCKRVWGDWEEDGFGTDPIEKENIMYKGHLNLMYGLYQLVTGSRRYEAEHAHLTRIIHDEIAANPFAGIVCEPDNYFVQCNSVAYLSLWVYDRLHGTDYRAATRAWLDFIQKDLIDPERGAFYLSYHPESGAVKPWISAYTTAWTLAMVHGMDPAFSERYYPRFKQTFVEVYDEGRKARVRETAGTDDADGGVGLASAFTLLLAREMGDQQLFDQLLNHLEPPAKPSIVSASLRYEHPGSLLFDELLFLAKVHAGFGALLRMPPPAAKLAGK
Protein: Pentatricopeptide repeat-containing protein At5g27270 (Protein EMBRYO DEFECTIVE 976) (O04647)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cytosolic sulfotransferase 5
Sequence:
MKSDFLTSTTHFNPSIFLPKIPSRNSRISIKSSSSSSKVRPDPWSLSDGNPEKPKPRYERPKHPLSDDDARRIIKKKAQYLSTLRRNQGSQAMTPKWIKRTPEQMVQYLEDDRNGQMYGKHVVAAIKTVRGLSQRRQGSDDMRFVMSSFVAKLSFRDMCVVLKEQRGWRQVRDFFSWMKLQLSYRPSVVVYTIVLRLYGQVGKIKMAEETFLEMLEVGCEPDAVACGTMLCTYARWGRHSAMLTFYKAVQERRILLSTSVYNFMLSSLQKKSFHGKVIDLWLEMVEEGVPPNEFTYTLVVSSYAKQGFKEEALKAFGEMKSLGFVPEEVTYSSVISLSVKAGDWEKAIGLYEDMRSQGIVPSNYTCATMLSLYYKTENYPKALSLFADMERNKIPADEVIRGLIIRIYGKLGLFHDAQSMFEETERLNLLADEKTYLAMSQVHLNSGNVVKALDVIEMMKTRDIPLSRFAYIVMLQCYAKIQNVDCAEEAFRALSKTGLPDASSCNDMLNLYTRLNLGEKAKGFIKQIMVDQVHFDIELYKTAMRVYCKEGMVAEAQDLIVKMGREARVKDNRFVQTLAESMHIVNKHDKHEAVLNVSQLDVMALGLMLNLRLKEGNLNETKAILNLMFKTDLGSSAVNRVISSFVREGDVSKAEMIADIIIRLGLRMEEETIATLIAVYGRQHKLKEAKRLYLAAGESKTPGKSVIRSMIDAYVRCGWLEDAYGLFMESAEKGCDPGAVTISILVNALTNRGKHREAEHISRTCLEKNIELDTVGYNTLIKAMLEAGKLQCASEIYERMHTSGVPCSIQTYNTMISVYGRGLQLDKAIEIFSNARRSGLYLDEKIYTNMIMHYGKGGKMSEALSLFSEMQKKGIKPGTPSYNMMVKICATSRLHHEVDELLQAMERNGRCTDLSTYLTLIQVYAESSQFAEAEKTITLVKEKGIPLSHSHFSSLLSALVKAGMMEEAERTYCKMSEAGISPDSACKRTILKGYMTCGDAEKGILFYEKMIRSSVEDDRFVSSVVEDLYKAVGKEQDV
Protein: Zinc finger protein 766 (Q5HY98)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger protein 791
- Zinc finger protein 431
- Histone H4 transcription factor
Sequence:
MAQLRRGHLTFRDVAIEFSQEEWKCLDPVQKALYRDVMLENYRNLVSLGICLPDLSIISMMKQRTEPWTVENEMKVAKNPDRWEGIKDINTGRSCAVRSKAGNKPITNQLGLTFQLPLPELEIFQGEGKIYECNQVQKFISHSSSVSPLQRIYSGVKTHIFNKHRNDFVDFPLLSQEQKAHIRRKPYECNEQGKVFRVSSSLPNHQVIHTADKPNRCHECGKTVRDKSGLAEHWRIRTGEKPYKCKECGKLFNRIAYLARHEKVHTGESPYKCNECGKVFSRITYLVRHQKIHTREKPHKCNKCGKVYSSSSYLAQHWRIHTGEKLYKCNKCGKEFSGHSSLTTHLLIHTGEKPYKCKECDKAFRHKFSLTVHQRNHNGEKPYKCHECGKVFTQVSHLARHQKIHTGEKPYKCNECGKVFTQNSHLANHQRIHTGEKPYKCHVCGKVFRHSSWFVQHQRSVHERVLTN
Protein: C-X-C chemokine receptor type 2 (CXC-R2) (CXCR-2) (GRO/MGSA receptor) (High affinity interleukin-8 receptor B) (IL-8R B) (CD antigen CD182) (P35407)
Organism: Rattus norvegicus (Rat)
Function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Growth-regulated alpha protein
- C-X-C motif chemokine 5
- C-X-C motif chemokine 2
- Chemokine
- C-X-C motif chemokine ligand 13
- C-X-C motif chemokine 3
- C-C motif chemokine 2
- H-2 class II histocompatibility antigen gamma chain
- C-C motif chemokine 5
- Stromal cell-derived factor 1
Sequence:
MGEIRVDNFSLEDFFSGDIDSYNYSSDPPFTLSDAAPCPSANLDINRYAVVVIYVLVTLLSLVGNSLVMLVILYNRSTCSVTDVYLLNLAIADLFFALTLPVWAASKVNGWIFGSFLCKVFSFLQEITFYSSVLLLACISMDRYLAIVHATSTLIQKRHLVKFVCITMWFLSLVLSLPIFILRTTVKANPSTVVCYENIGNNTSKWRVVLRILPQTYGFLLPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLVFLLCWLPYNIVLFTDTLMRTKLIKETCERQNEINKALEATEILGFLHSCLNPIIYAFIGQKFRHGLLKIMANYGLVSKEFLAKEGRPSFVGSSSANTSTTL
Protein: Cytochrome c2 (P86320)
Organism: Rhodovulum adriaticum (Rhodopseudomonas adriatica)
Function: Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
Subcellular location: Periplasm {ECO:0000269|PubMed:20697695}.
Interaction partners:
Sequence:
VDVSGDAAAGEKAFRQCITCHVVVDDSGETLAGRNAKVGPNLYKVPGRHAGQIEGFRYSDSMSQAGQNGLVWVEEEFVKYVQDPTGYLREYLGDSKARGAMTHKVRKEDEAVDIYAYLASLGVHEE
Protein: receptor protein-tyrosine kinase (EC 2.7.10.1) (Q677M1)
Organism: Gallus gallus (Chicken)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Membrane {ECO:0000256|RuleBase:RU000311}; Single-pass type I membrane protein {ECO:0000256|RuleBase:RU000311}.
Interaction partners:
Sequence:
MELGPLRVLTVLLCLPPVFTGLFISMDQPTLSIQKSVLTITTNDTLNITCSGQRAVYWSWPNNQSNAEKRLAVTGCSDGPFCKTLTLLRVIGNDTGDYRCLYGDSQAATTIYVYVQDYRSPFVTSVGDQLGIVYITKNKTVVVPCLGTVSNLNVSLHAKYPEKVFVPDGKSISWDNKKGFTIPSHLISYAGMVFCEAKIDNESYQSVIYIVAVVGYRIYDLTMNPHYQVELAVGEKLVLNCTVRTELNVGIDFKWDYPSIKEKRATIRDLKTTAGEIKTFVSTLTIDSVNLSDKGRYTCAASSGRMNMKNSSYFIIHESPFIHLEKMENVVEMKLGDTVSIPVKFKGYPSPEAKWYKNGKVMNANHTVKLGYTLVITDATEKDAGNYTVVLTNPTNKMQKRHTFTLLVNVPPQIGENALMAPVDSYKYGSTQTLTCTIYAVPPPAAVLWYWQLEEECTFSPQKVRLGANPYACRKWKVISERKGGNQVEIKQRVVTIAGKTKTVSTLVIQAANVSALYRCMATNRAGSSERVISFHVTRGLEINLQPRSQLTEKDNTSLQCTADKFTFEKLSWYKLSAHALQTPFGGLPMPVCKNLDALQKLNATVSNTNGENVTLELILRNISLQDGGDYVCIAQDKKAKTQHCLVKHLTVQEPMAPTLVGNLENQTTNIGETIEVSCTVNGIPPPNITWFKNGETLFEDSGIVLKDGNKTLTIRRVRKEDGGLYTCLACNILGCKKAEAYFSVEGAEEKTNLELIILVGTAVIAMFFWLLLVIILRTVKRANGGDMKTGYLSIIMDPDEVPIDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEYCKFGNLSAYLRSKRSEFVPYKTKSARFRQGKENYIGDISTDLKQRLDSITSSQSSTSSGFVEERSLSDVEEEDAGSEDLCKNPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSDNNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTFSELVEHLGNLLQANVRQDGKDYVVLPLSVSLNMEEDSGLSLPTSPASCKEEEEVCDPKFHYDNTAGISQYRQGSKRKSRPVSVKTFEDIPLVTTVKVVQEENQTDSGMVLASEELKTLEERDKQVKIPFSTLAPSKSNESVMSEASNQTSGYQSGYHSDDMDTMVCSSEDTELLCAQEASPTLPRVHGLVHDSPAPLVSPPL