wanglab/gogpt-training-data huggingface dataset:
Protein: Semaphorin-1A (Semaphorin-I) (Sema I) (Q24322)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in growth cone guidance through its role in axonal repulsion.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15282266, ECO:0000269|PubMed:8269517}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Plexin A, isoform A
- Plexin-B
- Tyrosine-protein kinase-like otk
- Semaphorin-2A
- Semaphorin-2A
- Fasciclin-2
- Receptor-type guanylate cyclase Gyc76C
- [F-actin]-monooxygenase Mical
- Neuroglian
- Ras-like GTP-binding protein Rho1
Sequence:
MLNSHNTNHNNNSASNSNYNKGHKMHLKSATAKATIMKHKLSKFYGYGWMQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVLKFVGNESVVDHFKLVTKDGNSLLIGARNTVFNLSIHDLVEQQRLVWTSPEDDTKMCLVKGKDEEACQNYIRIMVVPSPGRLFVCGTNSFRPMCNTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIYREPLQTEQYDSLSLNAPNFVSSFTQGDFVYFFFRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSCHNDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANAGEQKGFRNDMDLLDSRRQSKDQEIIDNIDKNFEDIINAQYTVETLVMAVLAGSIFSLLVGFFTGYFCGRRCHKDEDDNLPYPDTEYEYFEQRQNVNSFPSSCRIQQEPKLLPQVEEVTYAEPVLLPQPPPPNKMHSPKNTLRKPPMHQMHQGPNSETLFQFQPDGYNTQQSYRGRDNFGTLRSHQVMGDNYRRGDGFSTTRSVKKAVNNTNTRNRSLGRARRQPPRHGIVTQHRSNSPQQQQQQSQQPHSSSGSSPVMSNSSSSPAPPSSSPSPQESPKNCSYIYRD
Protein: Possible membrane protein (O50464)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Carboxyltransferase domain-containing protein
- Carboxyltransferase domain-containing protein
- Multifunctional 2-oxoglutarate metabolism enzyme
Sequence:
MSARRIRSWKRFDNRSANAAEPDPQLAGTGGRPKVSTRALAQVIERSSRIQGPAAQAYVARLRRAHPGASPAKIVAKLEKRFLSVVTASGAAVGAAATLPGIGTLAAWFAAAGEVVVFLEATALFVLALASVHAIPLDHRERRRALVLAVLVGDNTTAVADLLGPGRTSGGWVSETMASLPLPAISSLNSRMLKYVVKRFALKRGALMFGKLVPMGIGAIIGAIGNRLVGKKLVRNARSAFGTPPARWPVTLHVLPTVRDAS
Protein: Matrix Gla protein (MGP) (P83347)
Organism: Prionace glauca (Blue shark) (Squalus glaucus)
Function: Associates with the organic matrix of calcified cartilage.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
DSSESNEIDDVLFLGRRDANSFMKYPQLGN
Protein: Myelin protein zero-like 3 (Myelin protein zero-like protein 3) (Q6NW73)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MSVWSPAEVSVVSGSAVSLSCSFSSSSRVTSLMSVDWKFKPQSGGPAKLFFHFSSVAYPVEDERFRGRVKWTGSPSGGDASIQLLNATQNDNGTFSCSVRNPPDIQGNTAQTVLTVTPKRVSLTLTDVGVLLVCVVGPSAVVTLLLLSRICCCSEGPPALQHHSPIEVIAGEEYFYTQTQHKHSACCCYFKDSEYDEDEYMADKLHEHTITESQC
Protein: Ground-like domain-containing protein (Q3Y407)
Organism: Caenorhabditis elegans
Interaction partners:
- Cilia- and flagella-associated protein 20
- Ground-like domain-containing protein
- Ground-like domain-containing protein
Sequence:
MMPSFVFIFLLVSSQLATAAEEYKSQTTYPESAPAATTPQPPPPPPPPKPAPYVEQSAQPQQTAPPPPPAPYPQQAVPAPAPPPAPYPQHAVPAPAPPLASYPQNAVPVPAPPPAPYPQHAVPAPAPPPAPYPQHAVPAPAPYQQQPPPPPPPPHYPPPPPHYPPPPPAPHSAYIDHSAPRPAYIEHSAPPPQPQYPQQQPPQYPQQRQQHSYNAGPRTYHEEPQPYPAKFEYVDYPAPTTRRPYPYPSFEVLPHHEEYEPRSTRRPTTTEEPTTTSRKPRPGWKGDTEYNYPERNLPLKGCFYNNHGYACCNLKLQNKMEELADELLNNGTFHRCNVQKLANDLQDKVESAFKEDFETVVGLSDFAERIHFREHYVCKIEVNGRYMLAWATPDDIGTRRKRGANSTSDDIHEYNF
Protein: Frazzled (Q94538)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAITTNRSSRTLWNWLLSSCLIFQLIGSSLASQALSFTLEPQDAVVPEGHSVLLQCAGTASIGRGGKSKSNLPSSVSIRWRGPDGQDLVIVGDTFRTQLKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLNIKKPSDPGVENSVAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIWGKPKPVIRWLKNGDLITPNDYMQLVDGHNLKILGLLNSDAGMFQCVGTNAAGSVHAAARLRVVPQGVKIKKRKSQGHSTKSLQTFDNLTKRRKPFNSGEQLRTKSGGSFPFPDEDDDLDDNDSGTTRLRIPSGKLPKFEQPLNDRRFNILNAGSALPLDNQSKSYEDDDDDYDEDDPAKEALLEAYKQGEDAHKILDSWQQSKSKKSQQQKQSPASPDSPEQDPSVPHPGGKPLDSGLQARLPSQPRDLVAQIVKSRFVTLSWVEPLQNAGDVVYYTVYYKMNNSEREQKMVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFGSGASSAPLEVSTQPEVNIAGPPRNFEGYARSHKEIYVKWEEPTVTNGEILKYRVYYSENDSGADLYHDSTALEAVLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTPSEPPNNVTLEVTSSSSITVHWEPPAEEDRNGQITGYKIRYRKFKDAPQVKSTPANIRYFELSNLDRNAEYQVKIAAMTVNGSGPFTEWNRANTLENDLDETQVPGKPIWISIHPGANNIALHWGPPQHPEIKIRNYVLGWGRGIPDENTIELKETERYHILKNLESNMDYVVSLRARNVKGDGPPIYDNIKTRDEEPVDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNKNQHVTDNRHYTVSYGITGSNRYRYHNTTDLNCMINDLRPNTQYEFAVKVVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVEAFAGEETMLMLPNLKPYTTYYFKVQARTTKGANNAPFSALVSYTTSAAVTMQEPDTIAKGIDNEKLLYIIIAATAVVLLVVLLGVLLLCRRKPQSSPEHTKKSYQKNNVGVPKPPDLWIHHDQMELKNIDKGLHTVTPVCSDGASSSGALTLPRSVVHSEYEVETPVPGHVTNSLDKRSYVPGYMTTSMNGTMERPQYPRTQYSHQNRSHMTMEAGLSQQSLTQPQSNSMAQTPEHPYGGYDANFCNAGNAAAGNGCVSTIESSKRGHPLKSFSVPGPPPTGGATPVTKHTPAVTIRPQNQSPYKKPSFSAATPNRLQGGGSVVHSTDEIQRLAPSTSTEELNQEMANLEGLMKDLSAITANEFEC
Protein: DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide) (RPC14) (Q92399)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA-directed RNA polymerase II subunit rpb7
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerases I and III subunit RPAC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase II subunit rpb1
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerase I subunit rpa43
- DNA-directed RNA polymerase I subunit RPA12
- DNA-directed RNA polymerase II subunit RPB11
Sequence:
MSESVLLDEIFTVTSVDKQKYQRVSRITAVSGQNDMNLTLDINSQIYPLEKDATFSLQITSNLNSPDLKEAADYIMYGKVYRVEEAKDEKVSVYVSFGGLLMAIEGSHRKLYRLSLDHVYLLLRR
Protein: CBL-interacting serine/threonine-protein kinase 20 (EC 2.7.11.1) (SNF1-related kinase 3.6) (SOS2-like protein kinase PKS18) (Q9FJ54)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity). Required for the abscisic acid-mediated (ABA) signaling pathway involved in seed germination and growth elongation inhibition.
Interaction partners:
- Expressed protein
- Ankyrin repeat family protein
- Cysteine/Histidine-rich C1 domain family protein
- GCN5-related N-acetyltransferase 1, chloroplastic
- AT3g45210/T14D3_150
- Probable folate-biopterin transporter 8
- Protein kinase superfamily protein
- Protein PHYTOCHROME KINASE SUBSTRATE 1
- Spindle assembly abnormal protein
Sequence:
MDKNGIVLMRKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKLLSRILDPNPNSRIKIEKIMENSWFQKGFKKIETPKSPESHQIDSLISDVHAAFSVKPMSYNAFDLISSLSQGFDLSGLFEKEERSESKFTTKKDAKEIVSKFEEIATSSERFNLTKSDVGVKMEDKREGRKGHLAIDVEIFEVTNSFHMVEFKKSGGDTMEYKQFCDRELRPSLKDIVWKWQGNNNNSNNEKIEVIH
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (U3NG26)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSSHRKTKKPLPPTPEEDQILKKPLPPEPAAAPVSTSELKKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPES
Protein: FBD / Leucine Rich Repeat domains containing protein (Q9LFM0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEKSKRMELFIDRNLPACVSSLSVHLINLNVSNFGQTKLAYNDHIFGHLVHGSRISGFGLVCQVVWSLKLKDEIFVDVPRMVCLPSLKTLHLKGVMYVDEGSLQRLLSNCSLLEELVVERCNGANMRKFAVIIPQSSLSYLIVNMPKLEEADIARGSHDVKKLLKSISSVKRLSLYLEVNNNEDLYGDDIVFNELEHLKFRISRAVPRSMANVVGDSMDTLFCWKQMIDVPQCLLSSLQTFKWRTYFPTEEEKGLATYILAKSCRLKTARILIVSKLDPQKELEMKNELLSSCGSTTCNLDLVFKQFNDLL
Protein: Semenogelin 1 (Seminal vesicle secretory protein 2) (Q8BS30)
Organism: Mus musculus (Mouse)
Interaction partners:
- Seminal vesicle secretory protein 4
- Seminal vesicle secretory protein 5
- Seminal vesicle secretory protein 6
- Prostate and testis expressed protein 4
- Amine oxidase
- Seminal vesicle secretory protein 3A
- Prolactin-induced protein
- Serine protease inhibitor kazal-like protein, minor form
- 9530003J23Rik protein
- Protein-glutamine gamma-glutamyltransferase 4
Sequence:
MKSSVFVLSLLLILERQSAVVGQYGATKGHFQSSSSEGFMLGQKGRLSFGIKGGSDEAAEESLFMQSQRRVYGQGGGDMTQTRVSQEHTSVKGAALCRNGQVSQLKSQESQIKSYGQVKSSGQLKSGGSAFGQVKSSVSQIKSYGQLKSGGQLKSGGPAFGQVKSQESQIKSYGQLKSSGQLKSGGSAFGQVKSSVSQIKSYGQLKSGGSQVKSYGQTKSYGEEGQLNSFSQLKSQGAQLKSYGQQKSQQQSSFSQVKSQSSQLKSYGQQKSLKGFSQQTQHKGFAMDEGMSQVRKQFSDDDLSVQQKSTQQMKTEEDLSQFGQQRQYGQERSQSYKGYLEQYRKKVQEQQRKNFNPGNYFTKGGADLYQAQLKG
Protein: EOR-2 (G5EGD8)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MDQRNQKSLLPDFSANGFSGQFNGIPHGNTNAIMSTIQSLQMHSMGNQLLPHGDLQTDLQNQFLIEQFQLRAMQSMYNTFNNGNQKQPQASLTMSQFNSMTGNEPSTSSNVFSASIPTTSGTQINASQPMIPTTSMHNLAVQSSMMLENKLGQNLNLKTTQLAQTTIPQAQAAVEDWMKNICVDSLLDPKQAKTPSTTPSAQVSAGTTFNSTPAVSCATPLTATVSLATKPSEPSAASSMPTSSESVDATKGDAIDFDDEAHDDVDNIFGLSLSESDVRSGSMYRRPDSADRVHSPIDFTPPDSPQAELTFDEIFGISAPSTSAKAATKEKPVPKPRSEMVFHDVPSTSKDATPQRVPKPAPTAASKEEDDFVNNFVKPQNVPVYKQKAALMSLEARENARKEDPNYDAFEFEDDDDFVFGGPSADLRREPELTKKIEQKAKSVYITGVGFSIRNDKEKEYSSKKYYSKPSATHQPNFNDTINEKAFFTTADEIRAQKDQQLVCAFLKPEQVTSTECVRNMRKVTREEPMLPKFIIRVEQVQNQHEEPMTRRRYKRKKNKSDNDDSDFEDVAYRKRKTAKKVYTMHKENDPTFRRTVLDFSIGPCVSDEEKKRVSMFGPAEGILPKGTYVICKADMLKEDCAVWRVDNQNLLQKFPPFRDSKANRLVYRSSSTYSGWCEQISSQYFRVAVKIIKQTRSETTVEPEVPLAELFPASSVEWFKNPGTVFFEEETKVEPIDDDSILTEPRRVSLNTLVNAYLTQVFTKTHVESLIDDKDWTYSRSIAELETNNKQCEGLIKKRIPVEPKHNRWIAKYTRLAISKSSFHCFTKCQICKRKKPRRVIHFFDKTSCNEKLLVENLSSDIHDENEDDEEYPIVSDAISCGRCSMAVDFLHRMHHIKFHMLRICEDKLEEIGTSDIDLTSDKIVEKAKADKVWTLGVIQKYCDLWDQVRYEFRDV
Protein: Peroxidase 37 (Atperox P37) (EC 1.11.1.7) (ATP38) (Q9LDN9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000305}. Vacuole {ECO:0000305}. Note=Carboxy-terminal extension appears to target the protein to vacuoles.
Interaction partners:
- Berberine bridge enzyme-like 6
- Protein RALF-like 28
- UDP-glycosyltransferase 72E2
- Berberine bridge enzyme-like 7
- UDP-glycosyltransferase 72E3
Sequence:
MHSSLIKLGFLLLLIQVSLSHAQLSPSFYDKTCPQVFDIATTTIVNALRSDPRIAASILRLHFHDCFVNGCDASILLDNTTSFRTEKDAFGNANSARGFDVIDKMKAAVEKACPKTVSCADLLAIAAQESVVLAGGPSWRVPNGRRDSLRGFMDLANDNLPAPFFTLNQLKDRFKNVGLDRASDLVALSGGHTFGKNQCQFIMDRLYNFSNTGLPDPTLDKSYLSTLRKQCPRNGNQSVLVDFDLRTPTLFDNKYYVNLKENKGLIQSDQELFSSPDASDTLPLVREYADGQGKFFDAFAKAMIRMSSLSPLTGKQGEIRLNCRVVNSKSKIMDVVEDALEFASSM
Protein: Uncharacterized protein ycf68 (ORF133) (Q6ENB7)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Subcellular location: Plastid, chloroplast.
Interaction partners:
Sequence:
MAYSSCLNRSLKPNKLLLRRIDGAIQVRSHVDLTFYSLVGSGRSGGGTTAPLFSRIHTSLISVWRAISRAQVEVRPQWENGAPNNASSQTKNYEITLSFWGDGGIVPFEPFFHAFPGGLEKAAINRTSLILPS
Protein: Glial Lazarillo (Q9NAZ3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMSGQPLGSRVWLLSGVLLVTSAGTDAYGFGRCPNYPSMPKFNMSRVLGHWYEVERSFYLPEIASGCTTFQFEPYNKGEQSKFSNSKLAVAIKNINRITGNPNVNIGYATPENSRSSIMDFKFTTRFPDVIARLLPGSGKYQVLYTDYENFAILWSCGSIGSLGHSDQIWILGRDRDFEVDIRSKVYDVLKRLSLDPERLIISKNKQCPEAL
Protein: Pickpocket protein 11 (PPK11) (Q9VL84)
Organism: Drosophila melanogaster (Fruit fly)
Function: Part of a complex that plays a role in tracheal liquid clearance. In both larvae and adults, contributes to the behavioral response to salt. Probable role in sodium transport.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium channel protein Nach
- Pickpocket 29, isoform D
- Amiloride-sensitive Na+ channel
Sequence:
MSDVPGEDSPTHFYPVNFENYLRPKQSIKCQPLQRFKKPNERATNLYRNLKRLKILRWYNRVSKRFEEFPLPKFLGFLQARNDDGLCKRKTGFEIYCEMASIHGFHIFVGAKTWQRILWWLLICNAVLLSFTLVIMSLSMSKETPTIRFIDTMMKPTAEVPFPAVTICGFNTKEWMNSSQIVNQRNASWLELLEDLALPICPQIKICQWDNRMVNCLDQLQPIWTLDQRLCCSFNYNKQLFSSYLGVSFVLRSNDEILQSSKSAGFEVLIHESHEIPNGATPRVFVPGESDAHIMLRPYINRFTKNLKGLSLQKRGCYFSTERRLILSDVYNQINCLAECRTESILKSCGCIPPKSPIEKSWLICDLKQMQCVIDFDHDEIISGEQKNCDCLPPCEFNRYEFQSDIRFIKGMINNSIVNTSNQETTNEVRVRVYYDSAIAEELLLDVYENWLTFIGTFGGITGLFMGCSFVSVFELIFFSCVRPTCNWLTRQQILWRRRRNQRVGITESRSLGPAN
Protein: Aquaporin-4 (S5RRC8)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004415}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004415}. Cell projection {ECO:0000256|ARBA:ARBA00004316}. Endosome membrane {ECO:0000256|ARBA:ARBA00004608}.
Interaction partners:
- Aquaporin
- Aquaporin
Sequence:
MSVIESKTELFTVAGADTGDSGPGSGVVNPRKIVTTFERYIQPCLAEVLGCTLFIFVGCGSVIENAGVPGSIQPALAHGLALAIVIAVLGEISGGHFNPAVSVSVCVSGGLDVILLGPYILSQIVGGMTGAGLAKAVYSIISYDSAAGGAFNVVKTSGNIGSATVAEMVMTLFLSLVVCMGAVNSRTRTPLAPLCIGLTVTANILAGRSVSGGCMNPARAFGPAVMANYWEYHWIYWVGPVAGALITGSLVRLLFGDQKTRLVLK
Protein: Flavonoid 3'-monooxygenase (EC 1.14.14.82) (Cytochrome P450 75B1) (Flavonoid 3'-hydroxylase) (AtF3'H) (Protein TRANSPARENT TESTA 7) (Q9SD85)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Convert naringenin to eriodictyol and dihydrokaempferol to dihydroquercetin.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
Interaction partners:
- Naringenin,2-oxoglutarate 3-dioxygenase
- Dihydroflavonol 4-reductase
- Leucoanthocyanidin dioxygenase
- Flavonol synthase/flavanone 3-hydroxylase
- 2-oxoglutarate
- Flavonol 3-O-glucosyltransferase
- Chalcone--flavanone isomerase 1
- Probable flavonol synthase 6
- Probable flavonol synthase 4
- Flavonol synthase 3
Sequence:
MATLFLTILLATVLFLILRIFSHRRNRSHNNRLPPGPNPWPIIGNLPHMGTKPHRTLSAMVTTYGPILHLRLGFVDVVVAASKSVAEQFLKIHDANFASRPPNSGAKHMAYNYQDLVFAPYGHRWRLLRKISSVHLFSAKALEDFKHVRQEEVGTLTRELVRVGTKPVNLGQLVNMCVVNALGREMIGRRLFGADADHKADEFRSMVTEMMALAGVFNIGDFVPSLDWLDLQGVAGKMKRLHKRFDAFLSSILKEHEMNGQDQKHTDMLSTLISLKGTDLDGDGGSLTDTEIKALLLNMFTAGTDTSASTVDWAIAELIRHPDIMVKAQEELDIVVGRDRPVNESDIAQLPYLQAVIKENFRLHPPTPLSLPHIASESCEINGYHIPKGSTLLTNIWAIARDPDQWSDPLAFKPERFLPGGEKSGVDVKGSDFELIPFGAGRRICAGLSLGLRTIQFLTATLVQGFDWELAGGVTPEKLNMEESYGLTLQRAVPLVVHPKPRLAPNVYGLGSG
Protein: STAG1 cohesin complex component (Uncharacterized protein DKFZp781D1416) (Q68DW7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGKRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEHGAMPEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCLSNVNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRNKKGRPPLHKKRVEDESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPESEHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVRTGVRHAVRGLMEEDAEPIFEDVMMSSRSQLEDMNEEFEDTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF
Protein: Guanylate cyclase activator 1C (Guanylate cyclase-activating protein 3) (Guanylyl cyclase-activating protein 3) (Guca1c protein) (Q8UUX9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Guanylate cyclase
- Guanylate cyclase.
- Guanylate cyclase
- Peptidase S1 domain-containing protein
- Cyclic nucleotide-gated channel subunit alpha 1b.
- Cyclic nucleotide-gated channel subunit beta 1a.
- Guanylate cyclase
- Guanylate cyclase
- Guanylate cyclase.
- Guanylate cyclase.
Sequence:
MGAHASNLDEVLAEDMHYWYNKFMRESPSGLITLFELKNMLEMQGMTEEASSYVDQVFFTFDMDGDGYIDFVEYIAAVSLLLKGEINQKLKWYFKLFDQDGNGKIDRDEMETIFKAIQDITRSYEIPPDDIVSLIYERIDVNNEGELTLEEFITGAKEHPDIMEMLTKMMDLTHVLEIIVNGQKKKKE
Protein: Ribonuclease J 2 (RNase J2) (EC 3.1.-.-) (Q6GHG0)
Organism: Staphylococcus aureus (strain MRSA252)
Function: An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01491}.
Interaction partners:
Sequence:
MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGIDIVIPDISYVLENKEKLKGIFLTHGHEHAIGAVSYVLEQLDAPVYGSKLTIALIKENMKARNIDKKVRYYTVNNDSIMRFKNVNISFFNTTHSIPDSLGVCIHTSYGAIVYTGEFKFDQSLHGHYAPDIKRMAEIGEEGVFVLISDSTEAEKPGYNTPENVIEHHMYDAFAKVRGRLIVSCYASNFIRIQQVLNIASKLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPITEVDNYPKNEVIIIATGMQGEPVEALSQMAQHKHKIMNIEEGDSVFLAITASANMEVIIANTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMINIMKPEYFIPVQGEFKMQIAHAKLAAEAGVAPEKIFLVEKGDVINYNGKDMILNEKVNSGNILIDGIGIGDVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEDLLREAEEKVREIVEAGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI
Protein: N-(5'-phosphoribosyl)anthranilate isomerase (PRAI) (EC 5.3.1.24) (P00912)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Anthranilate phosphoribosyltransferase
- Tryptophan synthase
- Multifunctional tryptophan biosynthesis protein
- Imidazoleglycerol-phosphate dehydratase
- Anthranilate synthase component 1
- 3-isopropylmalate dehydrogenase
- Orotidine 5'-phosphate decarboxylase
- Phosphoribosylaminoimidazole carboxylase
- L-2-aminoadipate reductase
- Arginine permease CAN1
Sequence:
MSVINFTGSSGPLVKVCGLQSTEAAECALDSDADLLGIICVPNRKRTIDPVIARKISSLVKAYKNSSGTPKYLVGVFRNQPKEDVLALVNDYGIDIVQLHGDESWQEYQEFLGLPVIKRLVFPKDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSISDWVGRQESPESLHFMLAGGLTPENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANFVKNAKK
Protein: Potassium voltage-gated channel subfamily V member 1 (Voltage-gated potassium channel subunit Kv2.3r) (Voltage-gated potassium channel subunit Kv8.1) (P97557)
Organism: Rattus norvegicus (Rat)
Function: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2 (By similarity). {ECO:0000250}.
Interaction partners:
- Voltage-gated potassium channel subunit beta-3
- Voltage-gated potassium channel subunit beta-1
- FAU ubiquitin like and ribosomal protein S30 fusion like 2
- Ubiquitin-like protein FUBI
- Voltage-gated potassium channel subunit beta-2
Sequence:
MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCLTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSQGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNLQLLEILEYVCISWFTGEFILRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDIYARSIMEMLRLKGRERASTRSSGGDDFWF
Protein: Fibroblast growth factor receptor-like 1 (FGF receptor-like protein 1) (FGF homologous factor receptor) (FGFR-like protein) (Fibroblast growth factor receptor 5) (FGFR-5) (Q8N441)
Organism: Homo sapiens (Human)
Function: Has a negative effect on cell proliferation.
Subcellular location: Membrane {ECO:0000269|PubMed:12813049}; Single-pass type I membrane protein {ECO:0000269|PubMed:12813049}. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.
Interaction partners:
- Fibroblast growth factor 8
- Fibroblast growth factor 2
- Fibroblast growth factor 10
- Fibroblast growth factor 22
- Fibroblast growth factor 18
- Fibroblast growth factor 3
- Fibroblast growth factor 4
- Fibroblast growth factor 17
- Fibroblast growth factor 5
- Fibroblast growth factor 1
Sequence:
MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPPGTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQHIHYQC
Protein: Surf6l protein (Surfeit 6-like) (Surfeit locus protein 6) (Q7T3A6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASLAAKYDYLEKLTRKVCVSHKQEPKKRTYVPFRGGGNDANEAAPSKKKKKNKQKQVKGDNANANKNKPVVKGTPATTPPAQRKTVQNGTSVTQNKPGGAASKDFNAVDILRQRLHQKIEESRGQGTPKDPSSDEVKMKREKRKQERERRKRKRKEFRLKKLADAAGLQPVDVKEIKTEPEEDSTATSSVPAKKEQSFIVFNKMEVGEDYVDKGTKMMEKKKRKVKGTLTPLTGKNYKQLLTRIEARKAHLEQLREKDEGKAKKEEEKMKWTNVLYKAEGMKIKDNEKLLHASLKKKEKMKAQRKKKWAMRSEQVVEKMQKRQDKRKRNIKRRADAKIEKRKQKARKKGRVLPGDVKKAGL
Protein: Monothiol glutaredoxin (Q5AF81)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- BolA-like protein
- Fe-S cluster assembly protein DRE2
- Uncharacterized protein
- Iron-regulated transcriptional activator AFT2
- Iron-sulfur assembly protein 1
- Bola-like protein
- Suppressor of ferric uptake 1
Sequence:
MGVIEIESEQQFTELTKADPSKLIALYFHTPWAGPCKTMNQVFKTLADSKESDNSIIFLSINADELPEISEIFEVSAVPYFILIRNQTILKELSGADPKEFIQALNQFSNNTNSTTTSNNDNVQASINSTTANTNSNNTTTNAPEVEESEEALNERLNKLTKAAPIMLFMKGSPSSPQCGFSRQLVAILREHQVRFGFFDILKDDSVRQGLKKFSDWPTFPQLYINGEFQGGLDIIKESIEDDEKFFEHALEA
Protein: Immunoglobulin omega chain (Protein VPreB2) (V-set pre-B cell surrogate light chain 1B) (P13373)
Organism: Mus musculus (Mouse)
Function: Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.
Interaction partners:
- Immunoglobulin lambda-like polypeptide 1
- B-cell antigen receptor complex-associated protein alpha chain
- B-cell antigen receptor complex-associated protein beta chain
Sequence:
MAWTSVLLMLLAHLTGCGPQPMVHQPPSASSSLGATIRLSCTLSNDHNIGIYSIYWYQQRPGHPPRFLLRYFSHSDKHQGPDIPPRFSGSKDTARNLGYLSISELQPEDEAVYYCAVGLRSHEKKRMEREWEGEKSYTDLGS