wanglab/gogpt-training-data huggingface dataset:
Protein: Erythrocyte membrane protein 1, PfEMP1 (Q8IIZ6)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MVRTLDPEEELRGIEDTTAKHALDKIGEKIYEKAKKNAEQYRSQLHGRLSDARFEKAPKEQQTPSGPCGLNHEYHTNATNGKSYPCRTGKEERFSQVHGGECDKNKISGNKDDEGACAPYRRLNLCVRNLENISNYGKINNDTLLADVCLAALHEGAAISSDHGKYQETNNDVNANICTMLARSFADIGDIIRGKDLYRGVNGNDKLEKNLKKIFGIIYEGLTKANGKKGQKPAKDHYGDDENYYKLREDWWNNNRLMVWYAITCGAPKEAQYFRKTCGSGERTKDNCRCAIHGVPTYFDYVPQYLRWFEEWAEEFCRLRKHKLQNAIKNCRGENNEKYCDLNGYDCEKTIRGKKKLFEGADCKKCTVTCDNFVPWIKNQKQEFDKQKNKYAEEIKKAKADEETSSRNINNIYEKDFYERLKTHYGSVNEFLKKLNEERICKDEPKVKEEKADAVDFTKDETNGTFYRTTYCEACPWCGAEKVNGQNGKGGKWEPKNEACSQEEERIFDEQNITEIPVLTPEEGQSGILKKYSKFCKNGATGEKSKNGNQIETWKCYYDENENKKDGNGAINFCVLQNDKIGKKEEKSMHYHPFFWKWVTEMLIDSMYWRKELKSCINNKRGKCKNKKCNNDCKCYESWVQQKENEWKLILQHFKKQGGFSIFGNDYNYALKALLDVKEILTNIKDTYGNVKELEGINNMLEKENENNEQEASGGNNSQKKNTIDLMIDHEQKEAQNCKENNPDKCENTPGVRSQTPPANQDDVHDDVHDDLHDNEITRRDLNIKVDPQEVHHEEEVVEEEPEATKAVKEDTDGEGGSPKEDEEAAKRPSQEDPKVCETVDKALTETNLKDACPTKYGKNAPVSWKCIPTSGSGVTATGGGSGEPKGRHRREANPAKASDSNQGAICVPPRRRRLYIQKLHDWATAVSPQASGDKATQAAEPQASDKAAQVTEASASSSSSESNSVQTTPASTSSPSNSRDVDLVKAFVESAAVETFFLWDRYKKENTKRQGGGAGGLGGVPGVELPELPVSNSVEKTPQTQLASGDIPTPFLRQMFYTLGDYRDILVRGGNTSDSGNTNGSNNNNIVLLASENKQEMENIQEQLKVFFSNSGNQSSTVGRNPSQSRVTPASLWGDFAQYIWNGMICALTYEEKTSGSDDKGVKIEQNEGLKEALLEDKTNEPKKPQYQYKTVELKEENSDTQPITPGSSSPSGGDPINNPKLTQFVERPPYFRYLHEWGQNFCKKRKGMLENIKKECMKDSNSGSTGKKVQKCSCYGEHCDDQLKDDPSIFPSLNCPSCGRHCSFYKKWIKKKRTEFEKQSNAYEQQKTKYQRETKGAENTDHDNGFYTRLQNLPDAAAFLQKLGSCSKKVSEKDNEKIFEDTEQTFKDADNCKPCSQFKINCKSGDGHCDNNKGNHCQSKSSIEAKHIKKEGGLAEDIDMLVSDNGTTGFYDLSICISSGIFKGIRKDIWECGNVCGYNVCKPKNVNGETFEGQANGKNQIIFIRALFKIWLEYFLKDYNKINAKISYCKENGGTNICIKNCADKWIKLKKEEWGKIKEHYLEKKHEDGDNDMTSLVTNFLRDVQPQTDVNKAIEPCKGLENFEKSCGLHGDANEQNKNGYQDAIDCLLDKLRKEATSCPGKTSDKTQAKCQESTPPDDDESLEEEENTVGKQQPSFCPKPPEPKPEDEGGCETAQTTPKEPTADGGEGTENQPPVIKPEKEDTKSKDIQPQPPTAPPEEKNNLPQPSHPLPSDNTSDILKTTIPFGIALALTSIVFLYLKKKTKSTIDLLRVINIPKSDYDIPTKRSPNRYIPYTSGKYRGKRYIYLEGDSGTDSGYTDHYSDITSSSESEYEELDINDIYVPGSPKYKTLIEVVLEPSGNNTTASDTPSDTQNDIQNDGIPSSKITDNEWNTLKDEFISQYLQSEQPKDVPNDYSSGDIPFNTQPNTLYFDKPDEKPFITSIHDRNLYSGEEYSYNVHMVNTMDDIPKYVSNNVYSGIDLINDTLSGNKNIDIYDEVLKRKENELFGTNHVKQTSIHSVAKLTNSDPIHNQLELFHKWLDRHRDMCEKWENHHERLAKLKEEWENETHSGNIHPSDSNKTLNTDVSIQIHMDNPKPINQFTNMDTILEDLDKYNEPYYDVQDDIYYDVNDHDASTVDSNTMDIPSKVQIEMDVNTKLVKEKYPIADVWDI
Protein: 2S seed storage protein 3 (2S albumin storage protein) (NWMU2-2S albumin 3) [Cleaved into: 2S seed storage protein 3 small subunit; 2S seed storage protein 3 large subunit] (P15459)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This is a 2S seed storage protein.
Interaction partners:
- 12S seed storage protein CRB
- 12S seed storage protein CRC
- Oleosin 18.5 kDa
- 12S seed storage protein CRA1
- Defensin-like protein 192
- Oleosin 21.2 kDa
- B3 domain-containing transcription factor FUS3
- B3 domain-containing transcription factor ABI3
- B3 domain-containing transcription factor LEC2
- Cytochrome b-c1 complex subunit 10, mitochondrial
Sequence:
MANKLFLVCATLALCFLLTNASIYRTVVEFEEDDASNPVGPRQRCQKEFQQSQHLRACQRWMSKQMRQGRGGGPSLDDEFDFEGPQQGYQLLQQCCNELRQEEPVCVCPTLKQAARAVSLQGQHGPFQSRKIYQSAKYLPNICKIQQVGECPFQTTIPFFPPYY
Protein: Homeobox protein Vega2 (Vent) (Q9DGM9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Dharma.
Sequence:
MIPSKFSVEWLSQSFHDQEKCSTAAPGAPLTAAAGAGKAPASPANSCGYTDVESDDSEVEAGQNRRVRTKFTCDQISGLEKSFSKHRYLGATQRRKIAEKLHLSETQVKTWFQNRRMKLKREVQDMRAADFLYPAVFPPMTSLQHQSVGYYHQQQPQHITHPMLFTRCYF
Protein: Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (G3V8A4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR000381}.
Interaction partners:
Sequence:
MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEENFQGQEFKDHSRPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGSLGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQKLFEENYASPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPAMMAMHLKDFAVDGLVNVVGGCCGSTPDHIREIAEAVKNCKPRVPPDSVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDGMLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVSVCTRAYHLLVEKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFAFRGMDAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKDLLQLCEDLIWNRDAEATEKLLRYAQTHGKGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNREKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARVLNGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEILEEYEDIRQDHYESLKERKYLPLSQARKHSFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYEDAQNMLNILISRKKLRARGVVGFWPAQSVQDDIHLYAEGAVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFVAPLHSGVRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLGVTDLRKLRYEGIRPAPGYPSQPDHTEKLTMWRLANIEQATGIRLTESLAMAPASAVSGLYFSNVKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPILGYDTD
Protein: Homeobox-leucine zipper protein HAT3 (Homeodomain-leucine zipper protein HAT3) (HD-ZIP protein 3) (P46602)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor PAR1
- AT3G10250 protein
- Protein LITTLE ZIPPER 3
- Homeobox-leucine zipper protein HAT14
- Homeobox-leucine zipper protein HAT2
- Transcription factor PIL1
- Histidine-tRNA ligase
- Homeobox-leucine zipper protein HAT22
Sequence:
MSERDDGLGLSLSLSLGFNQKDPSSRLNPMPLASYASSSHMQHMQQSNYNHPQKIQNTWINMFQSSERNSDMRSFLRGIDVNRAPSTVVVDVEDEGAGVSSPNSTVSSVMSGKKSERELMAAAGAVGGGRVEDNEIERASCSLGGGSDDEDGSGNGDDSSRKKLRLSKEQALVLEETFKEHSTLNPKQKMALAKQLNLRTRQVEVWFQNRRARTKLKQTEVDCEYLKRCCENLTDENRRLQKEVSELRALKLSPHLYMHMKPPTTLTMCPSCERVAVTSSSSSVAPPVMNSSSPMGPMSPWAAMPLRQRPAAGSH
Protein: Grand meiotic recombination cluster protein 2 (Q06201)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable transcriptional activator involved in meiotic prophase and synaptonemal complex (SC) assembly.
Interaction partners:
- Protein ECM11
- Meiosis-specific protein SPO11
- Protein RED1
- MutS protein homolog 4
- Putative multicopper oxidase GMC1
- Synaptonemal complex protein ZIP1
- Protein ZIP2
- Uncharacterized protein YKR005C
- Sporulation-specific protein 22
- Sporulation-specific protein 16
Sequence:
MSDTTEVPRQSSENDQDNNLERTNSLKSPDVTNNIPSLFKLAAEWQINNPQETFQNHILENDVLKKINEITHLIRESYKDLSSQDGMMSKQQQEKMDWDLFCTVPVNIIEQYTKDMDEIYEKMERLAKQQRLWCESAFQIDVERCGDSILNAETWMKKKERHLEYKNIEMERSANEIKETIQRLTDDR
Protein: BLOC-2 complex member HPS5 homolog (Hermansky-Pudlak syndrome 5 protein homolog) (Protein pink) (dHPS5) (Q9VHN9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Has a role in the biogenesis of eye pigment granules. Eye pigment granules are specialized forms of late endosomes or lysosomes. Biogenesis of pigment granules in the eye requires molecular components required for protein delivery to lysosomes.
Interaction partners:
- Uncharacterized protein, isoform A
- Hermansky-Pudlak syndrome 4, isoform A
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- Dysbindin protein homolog
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- SNAPIN protein homolog
- Biogenesis of lysosome-related organelles complex 1 subunit 5
- GH27401p
- Biogenesis of lysosome-related organelles complex 1 subunit 4
Sequence:
MADAYCLTNFIDFSLSLSLPLKHHNRIKYTCFDISDSYIIFGASSGSLYLFNRNGKFLLLIPNKHGAITSLSISANSKYVAFATQRSLICVYAVNLSAQATPQVIFTHLDQSVQVTCIHWTQDEKQFYYGDSRGQVSLVLLSSFIGHSLLFNMTVHPLLYLDSPIVQIDDFEYLLLVSNCTKCILCNTEYEDYKQIGNRPRDGAFGACFFVSPQESLQPSRIYCARPGSRVWEVDFEGEVIQTHQFKTALATAPARIQRPGSGTDELDANAELLDYQPQNLQFAKVQRLNDDFLLAFTELGLYIFDIRRSAVVLWSNQFERIADCRSSGSEIFVFTQSGALYSVQLQTLQSHAVSLIQQSKLLPCANLLRQHVRYFADKAREDYELKQLNPLKQLLIERQEYELLNDISVIFDAITQCTGSALDTHSSGGSSATTERSLSGGSSSRAPPKGVYVLENAFCDNLKQPLKTGHFKDALLTVTGKFGKNIIKYKFNIFAEEQQQLVRELIPASERSLPFKDIKARYESGSEDQEEEIVRRCKKPAPQVPHISPEEKTLYNLYLIAKSAKFSRTQCVDRYRAVFDEYAAGELVNLLEKLAQVMVEHGDTPDQAQRNCYEMYFDYLDPEMIWEVDDATRDHIAAGFVLLNTSQNAEIVKCEHCSFPLRFDTSCQYHELGAVLLRYFWSRGEQLKCFDVVQSVPALLDVLAKFYLAEQNLTKVVAIVLNYGLPELLADVGKQLSVSAWGRCFEQFVELQRGGRLVCANCECISGVEQEQLGRHFFYNWNCFLNIALDHMSAGDTLALIFKWSSYIPNDAIDREFYSRCLLKG
Protein: Acyl-coenzyme A diphosphatase FITM2 (EC 3.6.1.-) (Fat storage-inducing transmembrane protein 2) (Fat-inducing protein 2) (Q8N6M3)
Organism: Homo sapiens (Human)
Function: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity). Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates such as oleoyl-CoA/(9Z)-octadecenoyl-CoA and arachidonoyl-CoA/(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA in the endoplasmic reticulum (ER) lumen (By similarity). This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (By similarity). Directly binds to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity). May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03230, ECO:0000269|PubMed:18160536}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03230}.
Interaction partners:
- Peptidase inhibitor R3HDML
- Seipin
Sequence:
MEHLERCEWLLRGTLVRAAVRRYLPWALVASMLAGSLLKELSPLPESYLSNKRNVLNVYFVKVAWAWTFCLLLPFIALTNYHLTGKAGLVLRRLSTLLVGTAIWYICTSIFSNIEHYTGSCYQSPALEGVRKEHQSKQQCHQEGGFWHGFDISGHSFLLTFCALMIVEEMSVLHEVKTDRSHCLHTAITTLVVALGILTFIWVLMFLCTAVYFHNLSQKVFGTLFGLLSWYGTYGFWYPKAFSPGLPPQSCSLNLKQDSYKK
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (A3RL80)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Interaction partners:
Sequence:
MSKPKVFFDITIDGKSAGRIVIELRADVVPKTAENFRALCTGEKGFGYKGSGFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFTLKHTGPGIMSMANAGPNTNGSPFFICTEKTSWLDGKHVVFGSVVDGMDVVRVVEGRGSSSGKCFAKIVIADCGQL
Protein: Cobalt transport protein CbiM (Energy-coupling factor transporter probable substrate-capture protein CbiM) (ECF transporter S component CbiM) (Q05594)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cobalt transport protein CbiQ
- Cobalt transport protein CbiN
- Cobalt import ATP-binding protein CbiO
- Cobalt-precorrin-5A hydrolase
- Cobalt-precorrin-6A reductase
- Cobalt-precorrin-7 C
- Cobalt-precorrin-5B C
- Probable cobalt-factor III C
- Cobalt-precorrin-2 C
- Cobalt-precorrin-4 C
Sequence:
MKLEQQLRQLSFSGLAAALLLMVVPQQAFAMHIMEGFLPPVWALAWWLLFLPCLWYGLVRLRRIVQEDNHQKVLLALCGAFIFVLSALKIPSVTGSCSHPTGVGLAVILFGPGVVAILGAVVLLFQALLLAHGGLTTLGANGMSMAVIGPVVGYLVWKMACRAGLRRDVAVFLCAMLADLATYFVTSVQLGVAFPDPHAGATGSVVKFMGIFCLTQIPVAIAEGLLTVMIYDQLTKRQVITVQGH
Protein: histidine kinase (EC 2.7.13.3) (A0A0H3CCG1)
Organism: Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus)
Interaction partners:
Sequence:
MGRHGGPAAAGPTAPSAVRAKAVNAPSQVFVRIAILAALLLLAVYTAFGVHRLQREAMAQPGGAPLAAKADLIAGRVDANLAAQRAGLSAAADLLKRDPGATMDAAETTLRAAGGEAAAVAVVSEAGVVAVAGRDDGADWKAAALAAGASGRTNWVGSVGETGRLYVATTTSLDRARAFVIASGDASRLVADPEKGESGALALPDGKLIAARGRGVQGAGALREAFALSIEDLGDGPAAVRGQAADGALLDVAVRPVAQGALLAVAAAPTRSVANLDRQVMEGAFSLLVPLGVGIALALLLMIQSRKAEVAHREFIDSERRFRLAVEAARCGIWEWDLNGDQVYLSDVTGAMFGWGGGGVVSGQDLLERISIDHRERVRQALANAAMYGAFDVSFRVPASEQGARSLWIDARGQGFGKPGSEGHARIIGVALDVTEERIAQARAQAAENRLRDAIESVSEAFVLWDRQGRLLMCNRNYRSVFSLEPKILKPGAARAEVNRFAALAIKQDHPAPDGAKGVREAEMMDGRWIQISERRTAEGGLVMTAADITAIKTQEEARRRNEEQLQNAVAGLERSQEQLAELARKYETEKVKAESANKAKSEFLANMSHELRTPLNAINGFSEIMMNEMFGPLGDQRYKGYSQDIHSSGQHLLALINDILDMSKIEAGKMNLKFESMHLEDVAEDAVRLVRNRAEAAGLKLDIDFPQLPEIEADYRAVKQVLLNLLSNAIKFTPRAGSVTVRAEVRRDPFGDLIKVSVTDTGIGIAKEDLARLAKPFEQVESQFSKTTQGTGLGLALTKSLITMHDGVLEMHSTPGEGTTVSFTLPVRHSDQKITRDFVAA
Protein: Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) (Q7TSQ8)
Organism: Mus musculus (Mouse)
Function: Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine.
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- Glycine cleavage system H protein, mitochondrial
- [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
- Glycine dehydrogenase
- Pyruvate dehydrogenase protein X component, mitochondrial
- [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Sequence:
MLYRLLSIVQRQRTSPGWQTWSSARSSTSTAEAHSIALPAQAQVVICGGGIMGTSVAYHLSKMGWQDIVLLEQGRLAAGSTRFCAGILSTARHSSVEQKMANYSNKLYHQLEQETGIQTGYLRTGSISLAQTQDRLISLKRINSRLNVVGIPSEIISPKKVAELHPLLNVHDLVGAMYVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLIKKGQVTGVETDKGQIECQYFVNCAGQWAYELGLSNEEPLSIPLHACEHFYLLTRPWDTPLQSNTPTIVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQNLREDWDHFEPLLSSLLRRMPALETLEILKLVNCPETFTPDMKCIMGESPVVQGYFVLAGMNSAGLSLGGGAGKFLAEWMVYGYPSENVWELDLQRFGALQSSRTFLRHRVMEVMPLIYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVPPNKDLLALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDEALESLQYLFCNDLDVPVGHIVHTGMLNEYGGYENDCSIARLTKRSFFMISPTDQQVHCWAWLNKYLPKDSNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPTLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGIDFIGRDALLQQKQTGVYKRLAMFILDDHDTDLDLWPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYVHNFSEDSGEEQVVTTDFINRGEYEIDIAGHRFQAKAKLYPVTSFFTHKRRKDDVELSDFHGK
Protein: Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (Parathyroid hormone 1 receptor) (Q9PVD3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Tuberoinfundibular peptide of 39 residues
- Parathyroid hormone 1a.
- Parathyroid hormone-like hormone
- Parathyroid hormone
- Parathyroid hormone-like hormone b
Sequence:
MGATLIVRTLGFLFCGTLLSFVYGLVDADDVLTKEEQIYLLFNAKRKCERAIKSKHKTSEGSCLPEWDGILCWPEGVPGKMVSTSCPEYIYDFNHKGHAYRRCDLNGTWELASHNNKTWANYSECAKFFPHYNQNQEREVFDRLYLIYTVGYSISLGSLMVATVILGYFRRLHCTRNYIHMHLFLSFMLRAISIFVKDVVLYSGSALQEMERITVEDLKSITEAPPANKTQFIGCKVAVTLFLYFLATNYYWILVEGLYLHSLIFMTFFSDRKYLWGFTLIGWGVPAMFVTIWASVRATLADTECWDLSAGNLKWIVQIPILTAIVVNFLLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAMPYTEVSGVLWQIQMHYEMLFNSVQGFFVAIIYCFCNGEVQAEIKKAWNRRTLALDFKRKARSGSNTYSYGPMVSHTSVTNVTARGPLALHLTNRLGHVTTNGHRNLPGYIKNGSVSENSIPSSGHELHIQEEEPSKTFQMEKTIQVVEEERETVM
Protein: Ubiquitin carboxyl-terminal hydrolase, putative (EC 3.1.2.15) (Q583R5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase
Sequence:
MRSVADGIGYAGSAEAAADLGSIKSCDNDPQLWMCLRCGLYCCGVHRKSHYDNSRMSGVGTDDKINGGHRIFFAVKPRWGTDVNSPAVGAPLPTVTINLCQVESPERRTVTMNNLKVSKVSFEKVGTYGIISCVECHEDPIKLPVRNSLPCLGVDLITLCENVAKVLHCVERNISLAPDYDEGSFGAPRARGVLDSGIATDTRRQNSNYETYSYVETNKQANSRAATSSNSRCVRARAGTLVEACISGFENRRNTCYFNSVLQCILQCNTFIDFMIRQKFTGSHTLVHHMSEMIGFMKSGPCAGDRQGIVDGLARALMGSLSEIVPMFGDGDQQDSQELFITLINGIADELDKGKSEEEKKGSQRVPFEGMLCTTVTCRGCKNQVKRDEVFMALSIPVTNSVEDSLEKLFERSTLNGDSQYACEVCFNKLSPAEQTKKNNDIRAENEARKLRKKANAEAKSLNCLYQDADVETSIGRFNGSLALHLLRFKCDDRGVYKVPGAVSFPKRLNLSKYIVGSAASGCGDTKMPQTIVQTNVNTHRSVSRPSNSLVHVSGGDGCTSSVEESTDNRRSQLDLELVGIISHVGSLHGGHYVAHVRSHTKPSMWFYCDDEEIYTVDESSVFEREQGVYMLFYDQLYH
Protein: Spermidine export protein MdtI (P69210)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the excretion of spermidine. Can also confer resistance to deoxycholate and SDS.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Spermidine export protein MdtJ
Sequence:
MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
Protein: DNA repair protein RAD1 (P06777)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD10 forms an endonuclease that specifically degrades single-stranded DNA.
Subcellular location: Nucleus.
Interaction partners:
- DNA repair protein RAD14
- DNA repair protein RAD10
- DNA repair protein RAD9
- DNA repair protein RAD2
- Replication factor A protein 1
- Protein CRT10
- DNA repair protein RAD4
- ATP-dependent helicase SGS1
- DNA mismatch repair protein MSH2
- General transcription and DNA repair factor IIH helicase subunit XPD/RAD3
Sequence:
MSQLFYQGDSDDELQEELTRQTTQASQSSKIKNEDEPDDSNHLNEVENEDSKVLDDDAVLYPLIPNEPDDIETSKPNINDIRPVDIQLTLPLPFQQKVVENSLITEDALIIMGKGLGLLDIVANLLHVLATPTSINGQLKRALVLVLNAKPIDNVRIKEALEELSWFSNTGKDDDDTAVESDDELFERPFNVVTADSLSIEKRRKLYISGGILSITSRILIVDLLSGIVHPNRVTGMLVLNADSLRHNSNESFILEIYRSKNTWGFIKAFSEAPETFVMEFSPLRTKMKELRLKNVLLWPRFRVEVSSCLNATNKTSHNKVIEVKVSLTNSMSQIQFGLMECLKKCIAELSRKNPELALDWWNMENVLDINFIRSIDSVMVPNWHRISYESKQLVKDIRFLRHLLKMLVTSDAVDFFGEIQLSLDANKPSVSRKYSESPWLLVDEAQLVISYAKKRIFYKNEYTLEENPKWEQLIHILHDISHERMTNHLQGPTLVACSDNLTCLELAKVLNASNKKRGVRQVLLNKLKWYRKQREETKKLVKEVQSQDTFPENATLNVSSTFSKEQVTTKRRRTRGASQVAAVEKLRNAGTNVDMEVVFEDHKLSEEIKKGSGDDLDDGQEENAANDSKIFEIQEQENEILIDDGDAEFDNGELEYVGDLPQHITTHFNKDLWAEHCNEYEYVDRQDEILISTFKSLNDNCSLQEMMPSYIIMFEPDISFIRQIEVYKAIVKDLQPKVYFMYYGESIEEQSHLTAIKREKDAFTKLIRENANLSHHFETNEDLSHYKNLAERKLKLSKLRKSNTRNAGGQQGFHNLTQDVVIVDTREFNASLPGLLYRYGIRVIPCMLTVGDYVITPDICLERKSISDLIGSLQNNRLANQCKKMLKYYAYPTLLIEFDEGQSFSLEPFSERRNYKNKDISTVHPISSKLSQDEIQLKLAKLVLRFPTLKIIWSSSPLQTVNIILELKLGREQPDPSNAVILGTNKVRSDFNSTAKGLKDGDNESKFKRLLNVPGVSKIDYFNLRKKIKSFNKLQKLSWNEINELINDEDLTDRIYYFLRTEKEEQEQESTDENLESPGKTTDDNALHDHHNDVPEAPV
Protein: DAB adaptor protein 1 (X6R4J9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSTETELQVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGKEGNHRFVAIKTAQAAEPVILDLRDLFQLIYELKQREELEKKAQKDKQCEQAVYQVPTSQKKEGVYDVPKSQP
Protein: DASH complex subunit dad4 (Outer kinetochore protein dad4) (Q50HP4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. May be necessary for growth under high osmotic stress.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P69851}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P69851}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:P69851}. Cytoplasm, cytoskeleton {ECO:0000305|PubMed:20624975}. Note=Associates with the mitotic spindle and the kinetochore. Kinetochore association occurs only during mitosis (By similarity). In the cytoskeleton, localizes to cortical microtubules (Probable). {ECO:0000250|UniProtKB:P69851, ECO:0000305|PubMed:20624975}.
Interaction partners:
- DASH complex subunit dad3
- DASH complex subunit spc19
- DASH complex subunit dad2
- DASH complex subunit dad1
- DASH complex subunit dam1
- DASH complex subunit ask1
- DASH complex subunit duo1
- Putative glycine cleavage system H protein, mitochondrial
- DASH complex subunit spc34
- Kinetochore protein ndc80
Sequence:
MNNPMEEQQSALLGRIISNVEKLNESITRLNHSLQLINMSNMNVELASQMWANYARNVKFHLEETHTLKDPI
Protein: Flagellin A (P0A0S1)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
Subcellular location: Secreted. Bacterial flagellum.
Interaction partners:
- Flagellar secretion chaperone FliS
- Flagellar motor switch protein FliN
- Flagellar hook-associated protein 2
- Flagellin B
- Flagellar hook-associated protein 1
- Flagellin B homolog
- Flagellar motor switch protein FliG
- Flagellar motor switch protein FliM
- Flagellar hook protein FlgE
- Flagellar basal body rod protein FlgB
Sequence:
MAFQVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQASSLGQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQGLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRIATGALITASGDISLTFKQVDGVNDVTLESVKVSSSAGTGIGVLAEVINKNSNRTGVKAYASVITTSDVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGVEAYTDQKGRLNLRSIDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINVVSASDSQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSLGSGVTTLRGAMVVIDIAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRDVDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLLT
Protein: Bifunctional polynucleotide phosphatase/kinase (EC 2.7.1.78, EC 3.1.3.32) (Q8ID74)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- DNA repair protein rhp16, putative
- transketolase
- GDP-L-fucose synthase
- 1-deoxy-D-xylulose-5-phosphate synthase
- indole-3-glycerol-phosphate synthase
- 3'-5' exonuclease
Sequence:
MVKRNLPQFELPNKNWNIFEDSLLYRIVKDKEDKIYKKIFSFDLDNTLILSRGFFKPAQNEKDYIFYSDIIEFLKKKHEENYKIMIFSNQKGVSSGKLSLSNLINRVDDIIEKIGLPLECYLALKNDKYRKPRIGMYLFATQNYKQNLDEVIYVGDNANRIYDEKFKQEFINHLKYIYSKNNVNININDIYKRLKKDYTDTDLKFALNINAKFYTPEDLFLNIKNHISTDFLFNPKYFNKELNEQENINKKNNHFYEICMKDYHSQNENINNKKNNTNNNIIPNNQYTTNEKYIPPNDQQKLIILIGPPGCGKTFLCTNYFSTYIRINMEEYKTISKCIQVLKEKLLQRKNVIIDNVNSLIKNRLLYINEAKKINQNIEIRLIYFNYSKELIIHLNTFKLITDKTNKFNDVPTIAIHSFYKYVQEPSKDENVDHIIVLKDENFVPTKFESEEQKKLFFMYLN
Protein: Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG) (Q9Y3Y2)
Organism: Homo sapiens (Human)
Function: Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). Plays an important role in the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH. The CHTOP-methylosome complex associated with 5hmC is recruited to selective sites on the chromosome, where it methylates H4R3 and activates the transcription of genes involved in glioblastomagenesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:19254951}. Nucleus, nucleolus {ECO:0000269|PubMed:19254951}. Nucleus, nucleoplasm {ECO:0000269|PubMed:23826332}. Nucleus speckle {ECO:0000269|PubMed:23299939, ECO:0000269|PubMed:23826332}. Note=Mostly associated with facultative heterochromatin (By similarity). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur (PubMed:23826332). {ECO:0000250|UniProtKB:Q9CY57, ECO:0000269|PubMed:23826332}.
Interaction partners:
- Spliceosome RNA helicase DDX39B
- SAP domain-containing ribonucleoprotein
- THO complex subunit 4
- THO complex subunit 5
- THO complex subunit 1
- THO complex subunit 2
- THO complex subunit 7
- Polymerase delta-interacting protein 3
- THO complex subunit 3
- UAP56-interacting factor
Sequence:
MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPTPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQSLKQRLGKSNIQARLGRPIGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALARPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND