wanglab/gogpt-training-data huggingface dataset:
Protein: Battenin (Q5XIH8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}. Lysosome membrane {ECO:0000256|RuleBase:RU361113}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361113}.
Interaction partners:
- CLN6, transmembrane ER protein
- Palmitoyl-protein thioesterase 1
- Protein CLN8
- Major facilitator superfamily domain containing 8
- Bis
- Tripeptidyl-peptidase 1
Sequence:
MGSSESSWRRLEDSEREETDSEPQTPPLDNLSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGPTPMPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQHTLLSMLGIPVLMLASYFLLLTSPEPLDPGGQDEAETAARQPLIGTETPESRPGTSWDLSLQERWTVFKGLLRYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWILALLQCLNLAFLLADVCLTFLPSIYLIFIVILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP
Protein: Probable pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) (P52647)
Organism: Escherichia coli (strain K12)
Function: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
Interaction partners:
- NADH-quinone oxidoreductase subunit C/D
- NAD-dependent dihydropyrimidine dehydrogenase subunit PreA
- Phosphate acetyltransferase
- NADP-dependent malic enzyme
- Bifunctional aldehyde-alcohol dehydrogenase AdhE
- Pyruvate kinase I
- Pyruvate kinase II
- Fumarate reductase iron-sulfur subunit
- Fumarate reductase flavoprotein subunit
- Phosphoenolpyruvate synthase
Sequence:
MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGLKNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTPFVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISQIATLKSRVPFIHFFDGFRTSHEINKIVPLADDTILDLMPQVEIDAHRARALNPEHPVIRGTSANPDTYFQSREATNPWYNAVYDHVEQAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAIGTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAEPLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARFTVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQGYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGGIFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAFFHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHSANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIPIWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQVAPEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKLERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLPSTPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLTALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFGGLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMMMYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQLTATGFWPLYRFDPRRADEGKLPLALDSRPPSEAPEETLLHEQRFRRLNSQQPEVAEQLWKDAAADLQKRYDFLAQMAGKAEKSNTD
Protein: Inositol-tetrakisphosphate 1-kinase 2 (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase 2) (Inositol-triphosphate 5/6-kinase 2) (Ins(1,3,4)P(3) 5/6-kinase 2) (OsITP5/6K-2) (OsITPK2) (EC 2.7.1.159) (OsITL1) (Protein DROUGHT- AND SALT-SENSITIVE MUTANT 3) (OsDSM3) (Q10PL5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 and participates in phytic acid biosynthesis in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds (By similarity). May be involved in the negative regulation of osmotic stress signaling.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:22038091}.
Interaction partners:
- Inositol polyphosphate multikinase IPK2
- Inositol-pentakisphosphate 2-kinase IPK1
- Os12g0183200 protein
- 3'
- Multiple inositol polyphosphate phosphatase 1
- Inositol-tetrakisphosphate 1-kinase 6
- Inositol-tetrakisphosphate 1-kinase 4
- Inositol-tetrakisphosphate 1-kinase 5
- Inositol-tetrakisphosphate 1-kinase 3
- Inositol-tetrakisphosphate 1-kinase 1
Sequence:
MRLHGEVSFDEDEEEVVMVPAAALSSSPLNGGAVPVTRLVVGYALTKKKVKSFLQPNLLLLARKKGINLVAIDDTRPLAEQGPFDVILHKITSKEWQQVLEDYHEEHPEVTVLDPPNAINHLNNRQSMLAEVSDLNLSSFYGEVCTPRQLVIMRDPSSIPTAVAMAGLTLPLVAKPLVVDGTSKSHELSLAYDEASLSMLDPPLVLQEFVNHGGILFKVYIIGETIQVVRRFSLPDVNTYDLLNNVGVYRFPRVSCAAASADHADLDPHISELPPRPLLEKLGKELRGRLGLRLFNIDMIRELGTKDRYYIIDINYFPGFGKMPGYEHIFTDFLLNLAQSKYKKCLSGG
Protein: Transmembrane 9 superfamily member (F4KIM7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endosome membrane {ECO:0000256|ARBA:ARBA00004337, ECO:0000256|RuleBase:RU363079}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004337, ECO:0000256|RuleBase:RU363079}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004653, ECO:0000256|RuleBase:RU363079}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004653, ECO:0000256|RuleBase:RU363079}.
Interaction partners:
Sequence:
MEFYRSSRRLQILGSVILLLSIHVAHSFYLPGVAPQDFEKDSISEAIGDELKVKVNKLTSIKTQLPYSYYSLPFCRPKKIVDSTENLGEVLRGDRIENAPYSFKMREAQMCNVLGRVMLDAKSAKAFKEKIDDEYRVNMILDNLPLVVPIERIDPGQGSPSVVYQLGYHVGLKGQYEGSKEQKYFMHNHLAFTVRYHRDMQTDAARIVGFEVKPYSVKHEYEGQWSEKTRLTTCDPHTKRLVVSSATPQEVENKKEIIFTYDVDFQESEVKWASRWDAYLLMSDNQIHWFSIVNSLMIVLFLSGMVAMIMLRTLYRDISRYNELETQEEAQEETGWKLVHGDVFRPPANSDLLCVYVGTGVQCLGMVLVTMIFAMLGFLSPSNRGGLMTAMLLLWVFMGLFAGYASSRLYKMFKGTEWKRIAFRTAFLFPAVVSAIFFVLNALIWGQKSSGAVPFGTMFALIFLWFGISVPLVFVGAYLGFKKPPLDDPVKTNKIPRQIPEQAWYMNPIFSILIGGILPFGAVFIELFFILTSIWLNQFYYIFGFLFLVFVILMVTCAEITIVLCYFQLCSEDYLWWWRSYLTSGSSAVYLFLYAAFYFFTKLQITKLVSAMLYFGYMLIASYAFFVLTGTIGFYACLWFTRLIYSSVKID
Protein: Probable G-protein coupled receptor 148 (Brain and testis restricted GPCR) (G-protein coupled receptor PGR6) (Q8TDV2)
Organism: Homo sapiens (Human)
Function: Orphan receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Cadherin-17
Sequence:
MGDELAPCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAKTSGIWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWLLAANSEVLMMLPRAMLTYLYLLRYRQLLGMVRGHLPSRRHQAIFTIS
Protein: Solute carrier family 35 member E1 (Q96K37)
Organism: Homo sapiens (Human)
Function: Putative transporter.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial antiviral-signaling protein
Sequence:
MAAAAVGAGHGAGGPGAASSSGGAREGARVAALCLLWYALSAGGNVVNKVILSAFPFPVTVSLCHILALCAGLPPLLRAWRVPPAPPVSGPGPSPHPSSGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEKQSTKVYLSLIPIISGVLLATVTELSFDMWGLVSALAATLCFSLQNIFSKKVLRDSRIHHLRLLNILGCHAVFFMIPTWVLVDLSAFLVSSDLTYVYQWPWTLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARKHLLPVTTADLSSKERHRSPLEKPHNGLLFPQHGDYQYGRNNILTDHFQYSRQSYPNSYSLNRYDV
Protein: F-box/LRR-repeat protein 15 (Q389V8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MADPIAVNFRRARFPNTPPAQLLTVIVSYRRGCAPLALLAVSPTARRAVEETGCAIGGLRVIHKNNDVKKCDDVRFVAPEELELAASNKQSLQSAVFGLWWYKRYPFTSLVVDHAGKENMPLIIRLKKALNIKKMVILKSAVTNEMMHIVSMARDLESLTVRNCFSESEASLCSVTSILNSRATNRRDARTFYLSGVTSLGVLRCLRSLTLFATPLSNQIMSYFCECTNLERVVVDSCCGLVSLECFAALQRLTHLSVLNCTITDEGLPPISKCFSLQYVMLDNCMKLRSLNCLGSLRNLRTLIVSRNRIPEEGVQGLRKLRDLEVLRFSVFNRPTAVEFISSLGSLVELDLRDNWVGDAGCASFVHCRQLQQLKLSCCRRVSDVRWLAALTCLRTLDLSHTNVRSRWLESLRACRYLVELNVAYCRDVVEVSFLSELRLLKHLDLSGTDIGEQNLDPIGRCEGLTFLLLKDCSSVKDLHFLETLRELVKLDTERTGIMDANVCQVVACKKLEFLSFRYCHLLTDVKCLEGLRNLKTLDLAGTNVTNEGISSLPKCVSLEYVDVSECCLITHLEFLRPLPNLQQVVADQMNLTDIGGLTGAPSLRRVTLNESKRLGTVGEVRLPYLQELSLRKSTISNAGIRSLLASCRSLQHLDMQHCHSVTELSALSQLPNLRELLLRNIRVTGEFMTHIASCVNLRKLQMTECADITDVNCLSALQSLEDIDLSRTSVTTEGIKGLSKCYALRKLNLSECRYVTNVNCLGKLPFLRELHLEKTNVTDKGIAGLSNCIQLETLALTKCSRITNVERLHSSLPHLEEFDVYGTSVDKFHRCLGGSQRTQHACSVL
Protein: Single-stranded DNA-binding protein WHY1, chloroplastic (DNA-binding protein p24) (PR-10a binding factor 2) (PBF-2) (Protein WHIRLY 1) (StWhy1) (Q9LL85)
Organism: Solanum tuberosum (Potato)
Function: Single-stranded DNA-binding protein that acts as a transcriptional activator of the pathogenesis-related gene PR-10a. Upon elicitation, binds a 30bp promoter sequence known as elicitor element response (ERE) and is required for PR-10a expression.
Subcellular location: Nucleus {ECO:0000269|PubMed:10948264}. Plastid, chloroplast {ECO:0000250|UniProtKB:Q9M9S3}. Note=Can localize to both chloroplast and nucleus. {ECO:0000250|UniProtKB:Q9M9S3}.
Interaction partners:
- Regulator of telomere elongation helicase 1 rtel1
Sequence:
MSNFSLSPSPTSGFSLNLQNPTKTSYLSFSSSINTIFAPLSSNTTKSFSGLTHKAALPRNLSLTCRHSDYFEPQQQQQQQQQQPQGASTPKVFVGYSIYKGKAALTVEPRSPEFSPLDSGAFKLSREGMVMLQFAPAAGVRQYDWSRKQVFSLSVTEIGSIISLGAKDSCEFFHDPNKGRSDEGRVRKVLKVEPLPDGSGHFFNLSVQNKLINLDENIYIPVTKAEFAVLVSAFNFVMPYLLGWHTAVNSFKPEDASRSNNANPRSGAELEWNR
Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-1) (PLC-1) (P32383)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Required for cell growth, osmoresistance and expression of GPD1.
Interaction partners:
- Inositol polyphosphate multikinase
- Phosphatidylinositol 4-phosphate 5-kinase MSS4
- Phosphatidylinositol 4-kinase PIK1
- Phosphatidylinositol 4-kinase STT4
- Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51
- Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1
- Inositol phosphosphingolipids phospholipase C
- Polyphosphatidylinositol phosphatase INP53
- Inositol monophosphatase 2
- Inositol monophosphatase 1
Sequence:
MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPTQLTMGQDGFTKFLKEQPYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGENGPVVCHGFLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVGTRTDKLPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSSYESANEQELRMKDDSTNSSSATNSSSMQRIKRIGLKKHADIINDVSNISGIHGIKFRNFSLPESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDTDLTFIKFMVISEETQIASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL
Protein: Paraquat-inducible protein A (Q38FZ8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSAACPLFAVWWSSVLLTGLEFPGLSTSFLTVKLDNASCSRVSIGEGSGTLNSSQLSVKIDQPSNVVCSAGIQLGAASTNITVDLAVHLNEITVGRELDDLCFTTNFIVDRCSLNVKVNDINMVPKFELFEMFKPIAQYIIEEKSETLLCNAHLPLLGNKFVISEVKPEKPAPPPVDGAVVLNTTPVFRGVTNVVNNIPVVFGVRLGAKMHEDTATRTNFTLPNGVNMTLYEDGALSPAISSLLASVEDALKALSLDGLVANISQMIPAVNVTNAVVDIPSSFTMSMDVVVTDVRCSDEAKLNCTIPCSDAVLLQNLRTVGLGDINKVAGNNMEDLLLPHVESLINSVLASNCTAGEERRPLPLLHAAEVRDVPPLSLWLTALCMSVVAFALGICWSIYRHRKDPATLADGSPISQCRALTEDGLLLLLTLSATFLLVWSNSTTAAAVVVGGEFNMLQLSLMEITSKIFKAGHVDLAIGFFFFSGVYPYVKLLCILVCTLGFRKPQHAFVRLLDCTGKFSFIDTFAMVVMVGGLELSGIAEVHIRPGFYCFLFATILTIFVGNYALYLWRRNTSVRLDQKCSPSEPSHSENDVVEAERDDELDTNSSKGKKCDLMRFVLRGLNGAATAVCVLLMWFIPCLRYNVGGLASVVQPDSRDMAMFELTSGSFTILTVCFLTTVLVPFLFAITYPNCSVTASWCAADALSVACIAGLVQLGKFVSYIIGEGMEAIYTAEAKLLWPMYPVFAFVIWQWILVIEREFKPVRWVWQHLTRPRSTLSSDVAADSREPIGEDKRHNRLFGFFFALFSTQFFHGSVKA
Protein: Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1) (Q8NEZ2)
Organism: Homo sapiens (Human)
Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Subcellular location: Late endosome membrane; Peripheral membrane protein. Nucleus.
Interaction partners:
- Vacuolar protein sorting-associated protein 28 homolog
- Ubiquitin-associated protein 1
- Tumor susceptibility gene 101 protein
- Multivesicular body subunit 12A
- Multivesicular body subunit 12B
- Vacuolar protein-sorting-associated protein 25
- Charged multivesicular body protein 2a
- Vacuolar protein-sorting-associated protein 36
- Charged multivesicular body protein 3
- Charged multivesicular body protein 4a
Sequence:
MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTINNLTININILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLLDEFWKNPPVLAPTSTAFPYLYSNPSGMSPYASQGFPFLPPYPPQEANRSITSLSVADTVSSSTTSHTTAKPAAPSFGVLSNLPLPIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAPL
Protein: Chromatin modification-related protein EAF3 (ESA1-associated factor 3) (Q12432)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00972, ECO:0000269|PubMed:14562095}.
Interaction partners:
- Enhancer of polycomb-like protein 1
- Chromatin modification-related protein YNG2
- Chromatin modification-related protein EAF5
- Transcriptional regulatory protein RCO1
- Chromatin modification-related protein EAF7
- Chromatin modification-related protein EAF6
- Histone deacetylase RPD3
- Protein AF-9 homolog
- Transcriptional regulatory protein UME1
- Histone acetyltransferase ESA1
Sequence:
MVDLEQEFALGGRCLAFHGPLMYEAKILKIWDPSSKMYTSIPNDKPGGSSQATKEIKPQKLGEDESIPEEIINGKCFFIHYQGWKSSWDEWVGYDRIRAYNEENIAMKKRLANEAKEAKKSLLEQQKKKKLSTSLGGPSNGGKRKGDSRSNASISKSTSQSFLTSSVSGRKSGRSSANSLHPGSSLRSSSDQNGNDDRRRSSSLSPNMLHHIAGYPTPKISLQIPIKLKSVLVDDWEYVTKDKKICRLPADVTVEMVLNKYEHEVSQELESPGSQSQLSEYCAGLKLYFDKCLGNMLLYRLERLQYDELLKKSSKDQKPLVPIRIYGAIHLLRLISVLPELISSTTMDLQSCQLLIKQTEDFLVWLLMHVDEYFNDKDPNRSDDALYVNTSSQYEGVALGM
Protein: GH09650p (Huntingtin-associated protein 40 kDa, isoform A) (Huntingtin-associated protein 40 kDa, isoform B) (Q9VXR6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform E
Sequence:
MDKLRGGSLGGGGSSSGAPSTAPGHEHHQLEQYQYPKNLIEQYLRASSKIKKFERAGFFKRFAPSVVDVQADFQRLAYSFEESGIQQYAAMCHIGYAKCESYGGAPQRESEAYLRAARSFLAAHNESGRLHLRTRHSGFREGAVHCYHRAADRAVDGCVFKAAILRELKQLQRQLDSTSSFASPTHQIHDLEISAETSGQRGDFRSALQHYDDIVDNVYERRGARMYGELLRRVEVLRLLLLVHLNLPPARQSPAHIKLIEYYYNLAQFESLPCSADDGGSAERPGAFVPEQQQYALAEITCAWVERKMCDLKHLLRDFGAEFGSLSDMERQLLAVMHAELARSY
Protein: HER-4 protein (Hairy-related 4, tandem duplicate 1) (Her4.1 protein) (Q90466)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Delta-like protein A
- Neurogenic locus notch homolog protein 1
- Achaete-scute homolog 1a
- Delta-like protein D
- ELAV-like protein
- Brain-type fatty acid-binding protein
- Hairy-related 5.
- Hairy-related 3.
Sequence:
MTPTITGSISSRETLLTNKLRKPMVEKIRRERINSSIEKLKTLLAQEFIKQQPDSRQEKADILEMTLDFLRRSQKSSAAGDGRSRCVQEAVSFLSQCPVQTQSHTRLMKLFLHMQTPADQHTRVDNPQTTETHANSSAKQHTPARSHIWRPW
Protein: MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog) (Q9Y6X3)
Organism: Homo sapiens (Human)
Function: Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with NIPBL/SCC2 which mediates the loading of the cohesin complex onto chromatin. Plays a role in sister chromatid cohesion and normal progression through prometaphase.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:16682347, ECO:0000269|PubMed:16802858}. Nucleus {ECO:0000269|PubMed:28167679}. Chromosome {ECO:0000250|UniProtKB:Q9D2X5}. Note=Binds to chromatin from the end of mitosis until prophase.
Interaction partners:
- Nipped-B-like protein
- Sister chromatid cohesion protein PDS5 homolog A
- Wings apart-like protein homolog
- Structural maintenance of chromosomes protein 3
- Sister chromatid cohesion protein PDS5 homolog B
- Sororin
- Cohesin subunit SA-1
- Double-strand-break repair protein rad21 homolog
- Structural maintenance of chromosomes protein 1A
- N-acetyltransferase ESCO1
Sequence:
MAAQAAAAAQAAAAQAAQAEAADSWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQENSVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEVHPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTISTLHDDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKMLDCSPILSSFQVILLEHIIMCRLVTGHKATALQEISQVCQLCQQSPRLFSNHAAQLHTLLGLYCVSVNCMDNAEAQFTTALRLTNHQELWAFIVTNLASVYIREGNRHQEVLYSLLERINPDHSFPVSSHCLRAAAFYVRGLFSFFQGRYNEAKRFLRETLKMSNAEDLNRLTACSLVLLGHIFYVLGNHRESNNMVVPAMQLASKIPDMSVQLWSSALLRDLNKACGNAMDAHEAAQMHQNFSQQLLQDHIEACSLPEHNLITWTDGPPPVQFQAQNGPNTSLASLL
Protein: SD17025p (Q9VP50)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKVSRGLFLLKQLPNVRNSSSGPTKPFKILNKHFDEISIPVPWGHISGKWYGPKHVRPIVGMHGWQDNAGTFDTLAPLLPSHLSFLSIDAPGHGLSSWLPPGTSYHSIDLVLITRRLMEEYNWDKISILAHSMSSINGFVFSALFPDKVDLFVGLDVLKPPVRSARGIVDSLTERIESALKLERRLKSGSEPPAYDWDQLVTRLHEGSNKSVSIDACKYLLQRNCKPSTHEPHKYYFSRDNRLKSSLFYTLHQEVPMEMARRIKCPHLFIKALQAPYYERKEYFDEVLAELQKNPLFEYHEVEGTHHVHLNEPEKVAPIINSFINRYRPL
Protein: Family with sequence similarity 120 member A (A0A494C0Y9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAP
Protein: Inositol oxygenase (EC 1.13.99.1) (Aldehyde reductase-like 6) (Kidney-specific protein 32) (Myo-inositol oxygenase) (MI oxygenase) (Renal-specific oxidoreductase) (Q9QXN4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Inositol monophosphatase 1
- Inositol monophosphatase 2
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- UDP-glucuronosyltransferase 2B15
- UDP-glucuronosyltransferase 1A1
- UDP-glucuronosyltransferase
- UDP-glucuronosyltransferase 2B37
- UDP-glucuronosyltransferase 2B1
- UDP-glucuronosyltransferase
- Aldo-keto reductase family 1 member A1
Sequence:
MKVDLGPDPSLVYRPDVDPEMAKSKGSFRNYTSGPLLDRVFTTYKLMHTHQTVDFVMRKRIQFGSFSYKKMTVMEAVDMLDDLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKILALWGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLENVLMSWGHDEYLYQMMKFNKFSLPSEAFYMVRFHSFYPWHTGGDYRQLCSQQDLDMLPWVQEFNKFDLYTKCPDLPEVKSLRPYYQGLIDKYCPGILSW
Protein: Chromosome transmission fidelity protein 18 homolog (hCTF18) (CHL12) (Q8WVB6)
Organism: Homo sapiens (Human)
Function: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. Interacts with and stimulates DNA polymerase POLH. During DNA repair synthesis, involved in loading DNA polymerase POLE at the sites of local damage.
Subcellular location: Nucleus {ECO:0000269|PubMed:12766176}. Note=Associates with chromatin during S phase.
Interaction partners:
- Sister chromatid cohesion protein DCC1
- Replication factor C subunit 3
- Replication factor C subunit 2
- Chromosome transmission fidelity protein 8 homolog
- Replication factor C subunit 4
- Replication factor C subunit 5
- DNA polymerase epsilon catalytic subunit A
- WD repeat and HMG-box DNA-binding protein 1
- DNA polymerase alpha catalytic subunit
- N-acetyltransferase ESCO1
Sequence:
MEDYEQELCGVEDDFHNQFAAELEVLAELEGASTPSPSGVPLFTAGRPPRTFEEALARGDAASSPAPAASVGSSQGGARKRQVDADLQPAGSLPHAPRIKRPRLQVVKRLNFRSEEMEEPPPPDSSPTDITPPPSPEDLAELWGHGVSEAAADVGLTRASPAARNPVLRRPPILEDYVHVTSTEGVRAYLVLRADPMAPGVQGSLLHVPWRGGGQLDLLGVSLASLKKQVDGERRERLLQEAQKLSDTLHSLRSGEEEAAQPLGAPEEEPTDGQDASSHCLWVDEFAPRHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPSRKPRPSVEPARVSKEATAPGKWKSHEQVLEEMLEAGLDPSQRPKQKVALLCGPPGLGKTTLAHVIARHAGYSVVEMNASDDRSPEVFRTRIEAATQMESVLGAGGKPNCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRPIICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKTDNDIRACINTLQFLYSRGQRELSVRDVQATRVGLKDQRRGLFSVWQEVFQLPRAQRRRVGQDPALPADTLLLGDGDAGSLTSASQRFYRVLHAAASAGEHEKVVQGLFDNFLRLRLRDSSLGAVCVALDWLAFDDLLAGAAHHSQSFQLLRYPPFLPVAFHVLFASSHTPRITFPSSQQEAQNRMSQMRNLIQTLVSGIAPATRSRATPQALLLDALCLLLDILAPKLRPVSTQLYSTREKQQLASLVGTMLAYSLTYRQERTPDGQYIYRLEPNVEELCRFPELPARKPLTYQTKQLIAREIEVEKMRRAEASARVENSPQVDGSPPGLEGLLGGIGEKGVHRPAPRNHEQRLEHIMRRAAREEQPEKDFFGRVVVRSTAVPSAGDTAPEQDSVERRMGTAVGRSEVWFRFNEGVSNAVRRSLYIRDLL
Protein: Uncharacterized protein (Q38BC0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQVIDMFALLRDQRVTPVVHLEALCALDGIRIEPGADPRELLCFYRMALMRWERIGSDTGKGGEEDVMSLSTTILDSLSPPASAVTSRGHPQMLMPSLIVCSSDGTGTLADHRMLARLKAQILIGRTILDRVVSFRK
Protein: G-protein coupled receptor-associated sorting protein 1 (GASP-1) (Per1-interacting protein) (Q920R4)
Organism: Rattus norvegicus (Rat)
Function: Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2 (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11597585}.
Interaction partners:
- Transcription factor 25
Sequence:
MTGAEVEPGAQAKAENKPGDENANAAEVEPEVPLVVRPKVRTQMMTGARPKVKPKGTPGARPKGETSSPGGAYAKCKPRSIPISRSKHDAQVWAPSKFRGESMSKMGKQCQISAADSPLVSNDSGAVAQAKCLSVDRELANMDTESIPKKASSPARFQPSFGPEEGTSMGSWYRPRPIPKGEAYENSDFKWADKSSGSSSFWNRDETSTRFRPRKSMKSNTRFRHMAKQEANTMSRHKNKQEFYNISSSDSEDESAKTPWFWAKDKPKVWSRPKEEPNTRSWFRSKKEVRVESTSGSECENHTKSLFWSGEEAKCRSKPRARKGVNMRARHQAKREAYSDVTSGSVDKNKKDSWFLPEEKANAFSKSKTKKEPRTRAMPREEVKTKARASTKQEARPEEEVLVGAWVLDTQDNTMGERISMKTTCVEEEPIVGDWFWSEEEASVDSETGLKSRPRAKEEQVSSFCLGSGKKTSMESGPKATSKSMPVAKDDEVIIGSWFWADDEEISLQADDESIFGSWFWGTGEKSLRSVGVSCEKMPKSGEKEVTDSWFWAGEVNTEAEMEEQASSASTKGTIFVPWFWSEKQAHMDLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSVEAEVNSKSSLEDEEEPIRSPWFGAREQPNMKYAAGVGYKPMAEAEEANKKSCVWAKEPCLYPTNRESLKSTLGEKEDTVDPWLWSNNYPRTETITGSWLWAAEEGNIDDETGEEIKLPTLEDNVFNSWSWKENEETVVEAPNREESKPEAEEEDIIGSWFWAGDEDRFQPAAKIKEENKIAPEDEDTVGSWFWGKEEASVEAVKGGTFESVSGIKEEKATGSWFWTDKAKIGAGPQTVETGSETEDEAIFESLIWAAKKDSMQTGVNRVSKPKDEGEGIESWLWSGDKATTESKTVTVSESSPENGKESIVKFGSRAKDEVINKTGSGDNCKFSTEAESIVGPWFWEGDEASFESNPVPVCKAACEPESSTEHEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSLNPFRFPKEAASLFAEMFGGKPKLVEVGTEREPEPQFPFQYDPSYRSVREIREHLKARESAQAENWSCNCIQCELRIGSEEFEELLLMMDRNRDPFIHEISKIAMGMRGASQFTRDFIRNSGVISLIEALMNYPSSRARTAFLENMIQMAPTYPDLNMIETYVCQVCEDTFDYDLDSSDQLSGLTMITHLTTTFDYHKVVVAYLAGFYYLLNSGNTTTRFHVLKLLLNLSESLVMTKRLLITDSVSEFMALFNREDSDENIQIILAIFENISKNIQKEALFADDEEEEEEEEAVNLEPLISAFREAEKFAKELKRKTDDQKSP