wanglab/gogpt-training-data huggingface dataset:
Protein: Protein HAPLESS 2 (GENERATIVE CELL SPECIFIC 1) (F4JP36)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for male fertility. Plays a role in pollen tube guidance and successful gamete attachment. Essential for the fusion of gametes during double fertilization, where one male gamete fuses with the egg to produce a zygote, and another male gamete fuses with the central cell to produce the endosperm. Mediates the fusion of cell membranes. Not required for pollen tube outgrowth.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:17079265, ECO:0000305|PubMed:23180860}; Single-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:16378100, ECO:0000269|PubMed:17079265, ECO:0000269|PubMed:23180860, ECO:0000269|PubMed:28137780}; Single-pass type I membrane protein {ECO:0000269|PubMed:28137780}. Note=Predominantly localized in a perinuclear ring (PubMed:17079265). Redistribution to the cell membrane is mediated by EC1 peptides after their secretion upon sperm arrival (PubMed:23180860). {ECO:0000269|PubMed:17079265, ECO:0000269|PubMed:23180860}.
Interaction partners:
- Protein GAMETE EXPRESSED 2
- Cation-chloride cotransporter 1
- Homeodomain-like superfamily protein
- Protein GAMETE EXPRESSED 1
- Transcription factor DUO1
- Zinc finger protein ZAT3
- Zinc finger protein ZAT2
- Protein KOKOPELLI
- Protein DMP9
- Protein DMP8
Sequence:
MVNAILMACILAGIFVGMFNEVDGIQILSKSKLEKCEKTSDSGNLNCSTKIVLNLAVPSGSSGGEASIVAEIVEVEDNSSSNMQTVRIPPVITVNKSAAYALYDLTYIRDVPYKPQEYHVTTRKCEHDAGPDIVQICERLRDEKGNVLEQTQPICCPCGPQRRMPSSCGDIFDKMIKGKANTAHCLRFPGDWFHVFGIGQRSLGFSVRVELKTGTRVSEVIIGPENRTATANDNFLKVNLIGDFGGYTSIPSFEDFYLVIPREAAEAGQPGSLGANYSMWMLLERVRFTLDGLECNKIGVGYEAFNTQPNFCSSPYWSCLHNQLWNFRESDINRIDRHQLPLYGLEGRFERINQHPNAGPHSFSIGVTETLNTNLMIELRADDIEYVFQRSPGKIINIAIPTFEALTQFGVAAVIIKNTGEVEASYSLTFDCSKGVAFVEEQFFIIKPKAVTTRSFKLYPTKDQAAKYICTAILKDSQFSEVDRAECQFSTTATVLDNGTQVTNPFQIPETQPKGFFDSIRILWTKIINGLVDFITGDTCRNKCSSFFDFSCHIQYVCLSWMVMFGLLLALFPITCLLLWLLHQKGLFDPCYDWWEDHFDLDHHRRLLPSRADVVNRHHHHHKHRHHHNHHRRTHQRHKHHHGQDDDVLQKMMLERDHSDSHYYHQLHRVHKDSKQKQRRRAKHGIVLPRDVHVERQRKQRLRES
Protein: Y-box protein (O46173)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MADAAESKPLAAEQQQQAQQQPEQQQNPPNPQEQDHEQEPLDELQGQQGQPAPPTKEVIATKVTGTVKWFNVKSGYGFINRNDTREDVFVHQSAIANNPKKAVRSVGDGEVVEFDVVIGEKGNEAANVTGPSGEPVRGSQFAADKRRNFRPWMKKNRRKDGEVEGEDAESSAQQQQQQAAPIVDGQPQQQVQSGPRQPRQNFRRGPPGGPPGGPRGGPRGPPGGAPGGPRRYNNYYLRQPRRGLGGGDGSAEPGVHDQNPEGLQRGEGQGPRRGGGPPAGPQRRFFRRNFNNGPPPPRRDGRIHSRPGTATPTTATSTSARGNQMALAVVRSSSQRRTALKSCKIQPQRALHRKGSERI
Protein: Seminal fluid protein 60F, isoform A (E1JGX1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GEO13347p1
- Seminal fluid protein 24Bb
- Seminal fluid protein 96F
- Testis-specific Plus3 domain b
- FI11009p
- Ejaculatory bulb-specific protein 2
- Ejaculatory bulb-specific protein 1
Sequence:
MCYHLFNYYLRSFATKFCAMSRLFILALILSILADSAFGNIDELLRSIDRALGGALGINPSLARSGFGIRTPSSEFSIGYGG
Protein: Large ribosomal subunit protein uL14 (60S ribosomal protein L23) (Ribosomal protein L17) (P62831)
Organism: Sus scrofa (Pig)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62829}.
Interaction partners:
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS9
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS3
- 40S ribosomal protein S30
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein uL10
- Ubiquitin-like protein FUBI
Sequence:
MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA
Protein: Zinc finger protein 239 (Zinc finger protein HOK-2) (Zinc finger protein MOK-2) (Q16600)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Retinol-binding protein 3
- Prelamin-A/C
Sequence:
MASTITGSQDCIVNHRGEVDGEPELDISPCQQWGEASSPISRNRDSVMTLQSGCFENIESETYLPLKVSSQIDTQDSSVKFCKNEPQDHQESRRLFVMEESTERKVIKGESCSENLQVKLVSDGQELASPLLNGEATCQNGQLKESLDPIDCNCKDIHGWKSQVVSCSQQRAHTEEKPCDHNNCGKILNTSPDGHPYEKIHTAEKQYECSQCGKNFSQSSELLLHQRDHTEEKPYKCEQCGKGFTRSSSLLIHQAVHTDEKPYKCDKCGKGFTRSSSLLIHHAVHTGEKPYKCDKCGKGFSQSSKLHIHQRVHTGEKPYECEECGMSFSQRSNLHIHQRVHTGERPYKCGECGKGFSQSSNLHIHRCIHTGEKPYQCYECGKGFSQSSDLRIHLRVHTGEKPYHCGKCGKGFSQSSKLLIHQRVHTGEKPYECSKCGKGFSQSSNLHIHQRVHKKDPR
Protein: 60S ribosomal protein L31 (Q8I463)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- 60S ribosomal protein L29
- 40S ribosomal protein S28e, putative
- 40S ribosomal protein S11, putative
- 40S ribosomal protein S15
- 60S ribosomal protein L3
- Small ribosomal subunit protein eS12
- 60S ribosomal protein L27
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S23, putative
- Small ribosomal subunit protein eS30
Sequence:
MVKGTVKKQKKTLKPVTKFITINLSKLTHKVCYKRKAPRAIKEIRSIAGKLMHTKDVRLDVKLNKFIWSKGVRNPPKRVRVKLERKRNEDEDSKEKMYTIVEHVMVDSYKGLVNECEANE
Protein: BCL6 corepressor (H7C231)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDASTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTNGERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDALGLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVPTDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKPSVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPFLEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPSKLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQRAMMRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERCEYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIELTGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
Protein: Ethylene-responsive transcription factor ERF043 (Q9M080)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- AT-hook motif nuclear-localized protein 11
- At3g10000
Sequence:
MADSSSDKEKKENNKQPVYRGVRMRSWGKWVSEIREPRKKSRIWLGTFPTAEMAMRAHDVAAMSIKGTSAILNFPELSKLLPRPVSLSPRDVRAAATKAALMDFDTTAFRSDTETSETTTSNKMSESSESNETVSFSSSSWSSVTSIEESTVSDDLDEIVKLPSLGTSLNESNEFVIFDSLEDLVYMPRWLSGTEEEVFTYNNNDSSLNYSSVFESWKHFP
Protein: Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) (BPR-2) (Q9UL12)
Organism: Homo sapiens (Human)
Function: Catalyzes the last step of the oxidative degradation of choline to glycine. Converts sarcosine into glycine.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:Q64380}.
Interaction partners:
- Glycine dehydrogenase
- Glycine N-methyltransferase
- Serine hydroxymethyltransferase, cytosolic
- Peroxisomal sarcosine oxidase
- Serine hydroxymethyltransferase, mitochondrial
- D-amino-acid oxidase
- Alanine--glyoxylate aminotransferase
- Dimethylglycine dehydrogenase, mitochondrial
- 5-aminolevulinate synthase, non-specific, mitochondrial
- Alanine--glyoxylate aminotransferase 2, mitochondrial
Sequence:
MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRRLLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQAHLKSPFDPNNKRVKGIY
Protein: Small regulatory polypeptide of amino acid response (A0A1B0GVQ0)
Organism: Homo sapiens (Human)
Function: Negative regulator of amino acid sensing and mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels and amino acids. Negatively regulates mTORC1 activation by inhibiting recruitment of mTORC1 to lysosomes upon stimulation with amino acids: acts by promoting the formation of a tightly bound supercomplex composed of the lysosomal V-ATPase, Ragulator and Rag GTPases, preventing recruitment of mTORC1. Acts as a regulator of muscle regeneration following injury by regulating mTORC1 activation (By similarity).
Subcellular location: Late endosome membrane {ECO:0000269|PubMed:28024296}; Single-pass membrane protein {ECO:0000305|PubMed:28024296}. Lysosome membrane {ECO:0000269|PubMed:28024296}; Single-pass membrane protein {ECO:0000305|PubMed:28024296}.
Interaction partners:
Sequence:
MGAKAPRGPKVAQWAMETAVIGVVVVLFVVTVAITCVLCCFSCDSRAQDPQGGPGRSFTVATFRQEASLFTGPVRHAQPVPSAQDFWTFM
Protein: Acidocalcisomal exopolyphosphatase, putative (EC 3.6.1.11) (Q38FJ8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- inorganic diphosphatase
Sequence:
MTAVVNEFLKRGVRALAARQDSVLVMGNEGGDMDTVIGSIFLAMYLEKRDVFGVGSYVPVLNFEKDDLPLRQDVVKLLSRHNVSTDSIYSVKQSGNGVDFLDLHQMKLPIVLYDHNKLSPEQVYLGERIVGVVDHHEDEQLYVDQTKCLRRICKTGSACTLVAELFNEAGLEVPCPELLLAPIVVDTVNFEPSQKRVTERDILASRLLVGRDDCGDYLTGMFKELMAWKNDIHCLTVPQHLRRDYKNFEFPFISAENKILRVGISSISCRSDELLSVHGVSSVSSNCIEFIKQRSIDMLLLTFAGERTPGSYCRQLGVVAKDEGLAALQAYCKKSPSGLDFTLLEDVTVNEWAFSIYELSDPSVSRKKLVPSLTSFLSVWNNL
Protein: Lbe homeodomain containing 132 aa C-terminal (Q7JMT6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
PQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVGLAAAAAAAGMVVPVPGSVPMGGAPPK
Protein: Regulator of nonsense transcripts 3A (Up-frameshift suppressor 3 homolog A) (B0S733)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. Binds spliced mRNA upstream of exon-exon junctions (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9H1J1}. Cytoplasm {ECO:0000250|UniProtKB:Q9H1J1}. Note=Shuttling between the nucleus and the cytoplasm. {ECO:0000250|UniProtKB:Q9H1J1}.
Interaction partners:
- Regulator of nonsense transcripts 1
- Uncharacterized protein.
- Protein mago nashi homolog
- Nonsense-mediated mRNA decay factor SMG5
- Telomerase-binding protein EST1A
- Eukaryotic initiation factor 4A-III
- SMG7 nonsense mediated mRNA decay factor.
- RNA-binding protein 8A
- Zgc:153681.
- Nuclear RNA export factor 1
Sequence:
MRSEKEQRTGSRERGSVEIQFRDCQDNAAVNPKHKEEKKEIFSKVVIRRLPPSLSKDQLQEHLSPLPSFDYFEFFPADQSLYPHLFSRAYINFKNPEDIIIFRDRFDGYVFIDNKGQEYPAVVEFAPFQKVSKKKLKKKDAKAGTIEEDPEYRRFLENYSCDEEKSMANPETLLGEIEAKTRELIAKRTTPLLEYIKNKKLEKQRIREEKREERRRRELEKKRQREEEKRKRREEERQKRKEAEKQKKLSEKEIKIKLLKKCDRDDDVDSDRLKDKGDSGETEKNRWEKPGGHTKSKDSKDNRSQMENDKEQREGHGRRQRDKDHRGRDEERKRQRHHYEFDKFMRRKEETKWGKGYCQDRAKKDQHHGYSYCPETGDKLGKEDREDMGSRKERIRNKDRPAMQLYQPGARNRKRMGSGNKTFDFPPISPEHAGEHCYKTVIGTGSEKSADE
Protein: Iron-sulfur clusters transporter ATM1, mitochondrial (EC 7.-.-.-) (J9VWU3)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of mitochondrial Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP (By similarity). Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). Plays a role during copper stress, in a manner dependent on the copper metalloregulatory transcription factor CUF1.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:29089435, ECO:0000305|PubMed:29420779}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGFGSCSRHALFTPAAFSGSFTTMTTSCFKRVYTAQIHGGDALGKRLPSVSSFSGQLPRHGLHRQSLAFFSTSHRRQTSPPPSPRTTSQSPTVPSKASTTPPTSLNTSKPIATESQDKTDWSIIVKLAGNIWPKNNPNVKFRVIGALTLLVAGKVLNVQVPFFFKTIVDSLNVPITESTTVWVLAGASIAGYGAARILTTLFGELRNAVFASVAQNAIRKVARETFEHLLNMDMKFHLERQTGGLTRAIDRGTKGISFILSSIVFHVIPTALEISMVCGILSWKFGWDFAAVTAITMLLYTWFTIKTTAWRTTFRKQANAADNKGATVAVDSLINYEAVKSFNNEKYEVAQYDTTLKAYEKASVKIATSLAALNSGQNFIFSSALTMMMLLGAQGIVKGTMTVGDLVLVNQLVFQLSLPLNFLGTVYRELRQSLIDMDVMFNLQSLNSAIKDTPTAKPLHLKGGEIEFRNVAFAYHPERPIFRDLSFKIPAGQKVAIVGPSGCGKSTVFRLLFRFYDSNSGQILIDGQDIKTVTLDSLRRSIGVVPQDTPLFHADILHNIRYGNLEATDEQVYEAARKAHVEGTIQRLPEKYATKVGERGLMISGGEKQRLAVARVLLKDPPVLFFDEATSALDVYTETELMRNINSILTGQGKTSVFIAHRLRTISDADLIIVLQDGYVAEQGTHEQLLAMPGGVYHRLWQAQLTESTQPTDEEIERQREELEVVDEKKKQ
Protein: Catalase (EC 1.11.1.6) (M4GGR6)
Organism: Humicola insolens (Soft-rot fungus)
Interaction partners:
Sequence:
MTCPFADPAALYSRQDTTSGQSPLAAYEVDDSTGYLTSDVGGPIQDQTSLKAGIRGPTLLEDFMFRQKIQHFDHERVPERAVNARGAGAHGTFTSYADWSNITAASFLNATGKQTPVFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIQFPDLIHSVKPRPDNEIPQAATAHDSAWDFFSQQPSTMHTLFWAMSGHGIPRSYRHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVWEEAQVLSGKNADFHRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEYAPLTKLGLLKLDRNPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYLDTQLNRNGGPNFEQLPINMPRVPIHNNNRDGAGQMFIHRNKYPYTPNTLNSGYPRQANQNAGRGFFTAPGRTASGALVREVSPTFNDHWSQPRLFFNSLTPVEQQFLVNAMRFEISLVKSEEVKKNVLTQLNRVSHDVAVRVAAAIGLGAPDADDTYYHNNKTAGVSIVGSGPLPTIKTLRVGILATTSESSALDQAAQLRTRLEKDGLVVTVVAETLREGVDQTYSTADATGFDGVVVVDGAAALFASTASSPLFPTGRPLQIFVDAYRWGKPVGVCGGKSSEVLDAADVPEDGDGVYSEESVDMFVEEFEKGLATFRFTDRFALDS
Protein: Cell division protein FtsX (P9WG19)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Part of the ABC transporter FtsEX involved in cellular division.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Cell division ATP-binding protein FtsE
- SsrA-binding protein
- Cell division protein FtsZ
- Conserved protein
- Cell division protein FtsQ
- Peptide chain release factor 2
- Possible conserved transmembrane protein
Sequence:
MRFGFLLNEVLTGFRRNVTMTIAMILTTAISVGLFGGGMLVVRLADSSRAIYLDRVESQVFLTEDVSANDSSCDTTACKALREKIETRSDVKAVRFLNRQQAYDDAIRKFPQFKDVAGKDSFPASFIVKLENPEQHKDFDTAMKGQPGVLDVLNQKELIDRLFAVLDGLSNAAFAVALVQAIGAILLIANMVQVAAYTRRTEIGIMRLVGASRWYTQLPFLVEAMLAATMGVGIAVAGLMVVRALFLENALNQFYQANLIAKVDYADILFITPWLLLLGVAMSGLTAYLTLRLYVRR
Protein: SoxNeuro, isoform B (M9PCZ7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription factor Zelda
- Protein pangolin, isoform J
- SOX domain-containing protein dichaete
- GEO07864p1
Sequence:
MLTMESDMKGSLLHATMPPHHTSAALHGHAASPYSALAPLMNLGQSHLTHSQLSHHNHHHHHMSAHIAASQSPNPLSSLQSSMANTLNGSQVGQQQQQQQQQQSSPLHSSSELSPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQHLSQQHQQIPQQHHTMQQQQQQHHLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSPPLPPYMPTAPQQQQQQQQQQQQLLNGRPSPTASGSSGGRSSAHSSGHTAAHSPALAAAYQLTPSAATSSATSAAAAAATAAAVAAAAAAGSSFAASASMLDMQQQHLEEQQQHHHLHYQQQQQQHYQQQQQQQQQLQHLPQQQQHQLYHHYHPGHEAAVAASAGLLDISTL
Protein: RE11278p (Q8IGX0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLQLHFYSNHAGRLVLGGGNRRPTDVLCYPLESIKEFEQISEAWKRLLAELLKKEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYALVYNGVRAAPLWDSEKQQLVGMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWRSVLHNQVMPLVSIGPDASLYDGIKILIHSRIHRLPVIDPATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRELKIGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDVSLRKANEHRNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPSGEGVGGSESSLRASDPVLLRKVAEVEIPATAAAATTTTPPRSPSAGSGNRSLIEDIPEEETAPARSDDADSDNNKSASEDKANNNQHDQTTTAATANGDSNNSPVEVSFADEAQEEEAADQVERSNCDDDDQPALAEIERKNASMDDDEDDGMSSAVSAASALGQSLTPAAQEMALVSE
Protein: Nucleosome assembly protein 1-like 4 (Q5U2Z3)
Organism: Rattus norvegicus (Rat)
Function: Acts as histone chaperone in nucleosome assembly.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q99733}. Cytoplasm {ECO:0000250|UniProtKB:Q99733}. Note=Present in the cytoplasm and excluded from the nucleus during G0/G1 phase, then relocates to the nucleus by the time cells are in S phase. Phosphorylated form localizes in the cytoplasm during the G0/G1 transition, whereas dephosphorylation leads to relocalization into the nucleus at the G1/S-boundary. {ECO:0000250|UniProtKB:Q99733}.
Interaction partners:
- Solute carrier family 22 member 18
- Pleckstrin homology-like domain family A member 2
Sequence:
MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEDDKLAGDMKNKVVIAEKEAAAVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKKEPIQPAECKQQ
Protein: Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) (P23685)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:1700476, ECO:0000269|PubMed:1785844, ECO:0000269|PubMed:17962412, ECO:0000269|PubMed:19332552, ECO:0000269|PubMed:9486131}; Multi-pass membrane protein {ECO:0000305}. Cell membrane, sarcolemma {ECO:0000269|PubMed:1700476}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit alpha
- Protein kinase cAMP-activated catalytic subunit beta
- Solute carrier family 8 member A2
- cGMP-dependent protein kinase.
- cGMP-dependent protein kinase.
- Solute carrier family 8 member A3
- Ryanodine receptor 2.
Sequence:
MLQLRLLPTFSMGCHLLAVVALLFSHVDLISAETEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVAENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSALACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLYGQPVFRKVHAREHPIPSTVITIAEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGILTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF
Protein: guanylate kinase (EC 2.7.4.8) (A0A8I5ZT32)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MLRRPLVGLAVAALGRVPVDGMAGPRPVVLSGPSGAGKSTLLKKLFQEHGSVFGFSVSRECLRTLKGKELRDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLHPIYISVQPPSMDVLEQRLRQRNTETEESLAKRLAAAQADMESSKEPGLFDLVIVNDNLDEAYVTLKQALSEEIKKAEGTEHA
Protein: Transmembrane protein fend (Protein forked end) (Q9GNL3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the normal targeting of ventral muscle, muscle 12, by motoneurons. May function as an axon guidance molecule involved in neuromuscular specificity.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MFHSLVLMACALAALSVAQGAGSARSKSLPLSLSLSVSVSSSLASASSPGAAADPTAAFTVTATAPTPASAPFAGKQLNRCRQSCYQQLSKDWHYCKDSVDCTNCCQKLVAPFELRILKAQRQESLVLTDIGWDEMIANASRQCLITWEVSGGGLIGNLLTDTARAELSLWPDTVYNIQVKCKHKLTGLMRRSIKLNVDTSQLVGTTTTTTTSKSSIQRQHLEQPVDHTDALEHSQHIRIPRPTDRVYIISALPTPSELGGVVYPAFGALAFFLALLVMFLFLRPQRKRFPLDADSADTATLIGRSSSSSRNSMDASTLHV
Protein: Nucleoporin (Q387L8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFPGSKRSREENSEGEGAIQETCSATFQHMSLELDEITKSVGSVNGAVLQSVVRKAQQLQRTLEGSRTSNAELWKQMSRCQANRVVTALSHARIADDSRQKTLSIGIMKEQLESSTALAVGELMKGFDSASKTTIALFSSQLEGEQQINEKLVERVQNLLRGALQALQVYSQRALDADLSALKKDVTIARLQSSLSFYQNASLRHHEEVLSLIDMVRILASKGKDADHVSSQLRQAKAHVRLLEKHLDLSGVVHAIVPPDFVPVQPGTEPPNPALQRTAPEYFALRLLQHRDVTLSELVDAWQRQESRIAEAEAKYVALKESVAVLRREALTVHEHFIEERQRREVVEHRLADLVRERIHPSGSESLSQQLTQLRMDYTRALDNSVQMATSLNMAREQLSDERAKCAELERTVQQLKDDSDAGKVVHTVAALRRYYEEEVSRLRNDTVNAETQCALAVAQAETQQRATREVEEALKITERTMTDVSSALQRVDSKRVDDKGRRHQGGSGVVQSGQLAAEVKDAVSRSEAHFQKAITSFEAMLNDKAAQREEDLRAFGQQVLRLIATFESLQSVASAANDRSENAAVVVDVTMERHQRDEIRSLLRETLAQTLHFLSNKLETTQMTETNLLDAAINDGQNVSMLLDKVREVTKERDLALERLARCEQLIDQHGLVAMDRVLMHEAPVDNSLDAVEASEQIAAMREQLTSLQAVRDAAMTELAALREEKQNISEDAEHTALQLKLLKNHNSDLLSSLQEHLTRETTLVEQLHRQQRQLQQIAADGEQSPPASNPEERVECMKGPLGQQLEELCSGFTAVKEQLVYLSETIPGNSGEKEAIESHLLRSGVRQVADTLRQALQRAELFRNSLQTETAALDVAEETEPLQGADTATEGEQGQLAALKEQLAAAMSAHESLIRGRDEELARLRAELAASASREESLRKGHEELQKQNADIQEKAMRLLHVNKQLVERVKTSRTEGESQSS
Protein: C40 family peptidase (NlpC/P60 family protein) (Probable cell wall associated hydrolase) (Q1PLH4)
Organism: Clostridium perfringens
Interaction partners:
Sequence:
MKKLFIWSGIISLIFPLLFFFLIIGGSGEQPTPVNPNPNLTEEQLNFISQIVSGAKQSYEETGIFPSITLAQAILESGWGRSGLAIKANNLFGIKADSGWKGKVLEMPTQEHVNGGIITIIARWRVYESWNESVIDHGKFFVENSRYKENGVLDAKNYVEQAQCIQKAGYATDPNYANQLIQVINDFGLNLYDMNGDVVGNDVIEKAIEAGMKWVGKSPYVWGGGRNQADVDAGRFDCSSLVHYCYASAGIQLGPRESVTTWSLINMGKPVPASEMKRGDLIFFDTAGRNGHIGIYLGNGKFLNDSSTQGVSIGDLNSAYWSRYFNGNVRRVVE