wanglab/gogpt-training-data huggingface dataset:
Protein: RNA polymerase II subunit B1 CTD phosphatase RTR2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2 homolog RTR2) (Regulator of transcription 2) (Q12378)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that regulates RNA polymerase II transcription. May have functional redundancy with RTR1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000305|PubMed:14562095}.
Interaction partners:
- GPN-loop GTPase 3
- GPN-loop GTPase 1
- Putative tyrosine-protein phosphatase OCA6
Sequence:
MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFCENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKSAAENSSDGFFIHSMYCNNYHSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDMYSVSLLEELVGSEVPIDTVKSLITSFKDLEFDDTYKNEPLPLDVYFGQLTTDEETCIE
Protein: Protein SHI RELATED SEQUENCE 4 (Q9SI19)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering. Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning. Promotes style and stigma formation, and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Electron carrier/iron ion-binding protein
Sequence:
MSNFEMAGTGSSRNNEEDNQQNTNWVWYKHTNNNLSTSHNNQIWQQPSLDLYPGQIDVCDMTTSSRSLTISCQECGNQAKKGCTHGRCRTCCKSNGLHCPTHVRSTWIPIAKRRERQQQLQTPTSNPTGGSGRVGKYRDINQHATLDSSGLEMGETRFPDEVSSDALFRCVRMSGTDDGEGQYAYQTTVGIAGHLFKGILYNQGPENKSMRSTQFYENPPRS
Protein: cDNA FLJ54613, highly similar to Mucolipin-1 (B4DFZ1)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Late endosome membrane {ECO:0000256|ARBA:ARBA00004107}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004107}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004155}.
Interaction partners:
Sequence:
MSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAYIAQCQDSPTSGKFRRGSGSACSLLCCCGRDPSEEHSLLVN
Protein: PIP2 protein (A0T2N8)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAKDIEVGGEFQAKDYHDPPPAPLVDAQELAKWSFYRAVIAEFIATLLFLYITVLTVIGYKTQTDPAKGGEDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLVRAIFYMGAQCLGAICGCGLVKAFQNSYYNQYGGGANSLAEGYSTGTGLAAEIIGTFVLVYTVFSATDPKRNARDSHIPVVLAPLPIGFAVFMVHLATIPITGTGINPARSLGAAVIFNQDKIWDDHWIFWVGPFIGAAIAAIYHQFILRASGAKALGSFRSSFAM
Protein: Glycine-rich protein 5 (AtGRP-5) (AtGRP5) (Q9LTP5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in organ growth by promoting cell elongation processes.
Subcellular location: Vacuole {ECO:0000269|PubMed:19434422}.
Interaction partners:
- Glycine-rich protein 23
- Glycine-rich protein 3
- Glycine-rich cell wall protein-like protein
- Expansin-A22
- Non-specific lipid transfer protein GPI-anchored 20
- Proline-rich extensin-like family protein
- Glycine-rich domain-containing protein 2
- Proline-rich extensin-like family protein
Sequence:
MASKSLFLVALLVGSFAFTSFASVANRKLKSGLEDQKTFFHHPGGGLGGGGGIGGGSGLGGGGGFGGGGGLGGGAGGGGGLGGGAGGGAGGGFGGGAGSGGGLGGGGGAGGGFGGGAGGGSGGGFGGGAGAGGGLGGGGGAGGGGGFGGGGGSGIGGGFGGGAGAGGGFGGGHH
Protein: Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1 homolog) (Protein GCP-WD) (B3H5K9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates microtubules organization in a centrosome-independent manner. Required for the spindle to be positioned correctly and for the function of gamma-tubulin in organizing phragmoplast microtubules. Component of active gamma-tubulin ring complexes (gamma-TuRCs) associated with cortical microtubules in interphase cells. Mediates gamma-TuRC recruitment to the nucleation sites and is important for determining the ratio of branched to parallel nucleation. May mediate the localization of GCP2 and GCP3 to the nuclear envelope.
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:19383896, ECO:0000269|PubMed:25438942}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:19383896}. Cytoplasm, cytoskeleton, phragmoplast {ECO:0000269|PubMed:19383896}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000269|PubMed:25438942}. Note=First detected in prophase on the nuclear envelope, where it appeared to cap the future spindle poles. Later detected along kinetochore microtubules (MTs) of the metaphase spindle, with more prominent signals toward the poles. In anaphase, detected with the shortening kinetochore fibers. In the developing phragmoplast, localized mainly toward the minus end of MTs. {ECO:0000269|PubMed:19383896}.
Interaction partners:
- Gamma-tubulin complex component 4
- Tubulin gamma-2 chain
- Gamma-tubulin complex component 3
- Tubulin gamma-1 chain
- Mitotic-spindle organizing protein 1B
- Gamma-tubulin complex component
- Gamma-tubulin complex component 2
- Gamma-tubulin complex component
- Spindle pole body component
- Spc97 / Spc98 family of spindle pole body
Sequence:
MMSNLVEPSWRLLAASGGDTVKLFDVSADSGDPCVLSYTPSPGCAVNSVKWNHTNLVVASTGEDKKISLWRKNGQSLGTVPVTGKDGGDSAEECLSAISFSKKGSRYICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATELKDPNGQVLRLLDYSRSSRHLLVTAGDDGTVHLWDTTGRSPKMSWLKQHSAPTAGVCFSPSNEKIIASVGMDKKLYTYDSGSRRSSSCIAYEAPFSSLAFGDNGYILVAGTSNGRVVFYDIRGKPQPVTVLHAFSNSEDVTSLSWQTSKPVIVNEKNYTSEMALLGSTVEDSVVIPDPLPSTTPSASQSAMAPGSRGVSASTVNASSVEQTPNRNHLWPSGPLGRLHALRANDSYNDDMGVFSPIIDVSSVEKWADSEGYNNKDHLVVDNKPSSLLFPSSSKGYSFGDNGSKEHPIFDWKPSSTSKQDDPRAAFSSFGSITPTASSKSEDSALTPPEAWGGDKFSEKFNQLANEKFSDKFSHLHAPSRLAVSSTGASTSGSMFSSSRDFPLSHGQTNFANASLEFPRIRDFSSTFETSSTQTDNNLPSSPLFTKGITAPGNIDSLRLSPNFTRRFSTYAERISTTSSFSDGASLSLGGSPKIKKTGSETREEVLNHLLARPETVVATEAGAMPLMNQGGLKQSQTDQQQVMGSSNFTLQLFQRTLEGTLDSFQNSIHDDVRNLHIEILRQFHMHEMEMSKVLSSILENQAEQMKELKLLRKENQELRQRL
Protein: Synaptotagmin-2 (Synaptotagmin II) (SytII) (P29101)
Organism: Rattus norvegicus (Rat)
Function: Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Plays a role in dendrite formation by melanocytes.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:9867811}; Single-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane {ECO:0000250|UniProtKB:P21707}; Single-pass membrane protein. Cytoplasm.
Interaction partners:
- Vesicle-associated membrane protein 2
- Multifunctional fusion protein
- Stonin-2
- Vesicle-associated membrane protein 3
- Synaptosomal-associated protein 23
- Complexin-1
- Vesicle-associated membrane protein 1
- Synapsin-1
- Syntaxin-1B
- Otoferlin
Sequence:
MRNIFKRNQEPIVAPATTTATMPLAPAAPADNSTESTGTGESQEDMFAKLKDKFFNEINKIPLPPWALIAMAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
Protein: Endonuclease 8-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (Endonuclease VIII-like 2) (Nei homolog 2) (NEH2) (Nei-like protein 2) (Q6R2P8)
Organism: Mus musculus (Mouse)
Function: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Kelch-like ECH-associated protein 1
- DNA repair protein XRCC1
- Endonuclease 8-like 1 lyase Neil1)
- N-glycosylase/DNA lyase
- DNA polymerase beta
- Endonuclease III-like protein 1 lyase)
- Bifunctional polynucleotide phosphatase/kinase
- F-box/WD repeat-containing protein 1A
- Cullin-3
- Flap endonuclease 1
Sequence:
MPEGPSVRKFHHLVSPFVGQKVVKTGGSSKKLHPAAFQSLWLQDAQVHGKKLFLRFDPDEEMEPLNSSPQPIQGMWQKEAVDRELALGPSAQEPSAGPSGSGEPVPSRSAETYNLGKIPSADAQRWLEVRFGLFGSIWVNDFSRAKKANKKGDWRDPVPRLVLHFSGGGFLVFYNCQMSWSPPPVIEPTCDILSEKFHRGQALEALSQAQPVCYTLLDQRYFSGLGNIIKNEALYRARIHPLSLGSCLSSSSREALVDHVVEFSKDWLRDKFQGKERHTQIYQKEQCPSGHQVMKETFGPPDGLQRLTWWCPQCQPQLSSKGPQNLPSS
Protein: Pentatricopeptide repeat-containing protein At5g21222 (SNF1-like protein kinase AtC401) (Q8S9D1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
- F21J9.19
- Zinc finger
Sequence:
MSEPKVRRWVGKYEVGRLIGECNFGKLRSAVDTETGDPVALMILDKDKVLKHKMAEQIKREISIMKLINHPNVVQLYEVLASKAKIYIVLEFISGGKLFDKIKNDGRMNEDEAQRYFQQLINAVDYCHSRGVYHRDLKPENLLLDAQENLKVAEFGLIALSQQAGGDGLRHTACGNPDYAAPEVLNDQGYDGAKADLWSCGVILFVLLAGYLPFEDSSLTTLYKKISSADFSCPPWLSSGVKNLIVRILDPNPMTRITIPEILEDVWFKKDYKPAVFEEKKEANLADVEAVFKDSEEGRVQLRSFPCVICSGGTTCGDVRSRTKLMNGLIERGRPQEAHSIFNTLIEEGHKPSLITYTTLVTALTRQKHFHSLLSLISKVEKNGLKPDTILFNAIINASSESGNLDQAMKIFEKMKESGCKPTASTFNTLIKGYGKIGKLEESSRLLDMMLRDEMLQPNDRTCNILVQAWCNQRKIEEAWNIVYKMQSYGVKPDVVTFNTLAKAYARIGSTCTAEDMIIPRMLHNKVKPNVRTCGTIVNGYCEEGKMEEALRFFYRMKELGVHPNLFVFNSLIKGFLNINDMDGVGEVVDLMEEFGVKPDVVTFSTLMNAWSSVGDMKRCEEIYTDMLEGGIDPDIHAFSILAKGYARAGEPEKAEQILNQMRKFGVRPNVVIYTQIISGWCSAGEMKKAMQVYKKMCGIVGLSPNLTTYETLIWGFGEAKQPWKAEELLKDMEGKNVVPTRKTMQLIADGWKSIGVSNSNDANTLGSSFSTSSKLNIPNNIASSRSPLFLKGMPEKPKLCIKSQFGLRQTLLVVLCRDQIGEAGRFCKFM
Protein: Ceramide kinase-like isoform 4 (G0XYF2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MFRGRRRSRVGALEEAPPENPKAAAEPERVLLRGIFEIRRESCDVALGERALRWRRIQPELPAGSTNALAHSLFGTPHVVTATMHIILGHIRSVDVCTFSSAGKLLCFGFSAMFGFGGRTLALAEKYRWMSPSQRRDFAIIKALAKLKPEDCKISFLLAGCSQNKQERKSQRSAESDCGGHWQTIQGQFLNISIMAMPCPCSMAPRGFTPDTRLHNGSMALRVVRNTTRSEFVKHLKRHSSVKNQFNFPFVETYIIEEVKIHPKSNSNGYSPQEEGGNHTTASEHGFPWNVDGDLMEAASEVHIRLHPRLIRLYGGSLEEMNDCKVACDCI
Protein: Trihelix transcription factor DF1 (Q9C6K3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription repressor that negatively regulates root hair growth by directly binding RSL4 promoter and repressing RSL4 expression. Required for the synthesis of seed coat mucilage.
Subcellular location: Nucleus {ECO:0000269|PubMed:29439132}.
Interaction partners:
- non-specific serine/threonine protein kinase
- Histone-lysine N-methyltransferase ASHR1
- Ubiquitin fusion degradation UFD1 family protein
- Ethylene-responsive transcription factor ERF112
- Probable E3 ubiquitin-protein ligase RHA1A
- AT3g28220/T19D11_3
- Membrane-anchored ubiquitin-fold protein 4
- At2g29070
- Putative ubiquitin-dependent proteolytic protein
- non-specific serine/threonine protein kinase
Sequence:
MMQLGGGTPTTTAAATTVTTATAPPPQSNNNDSAATEAAAAAVGAFEVSEEMHDRGFGGNRWPRQETLALLKIRSDMGIAFRDASVKGPLWEEVSRKMAEHGYIRNAKKCKEKFENVYKYHKRTKEGRTGKSEGKTYRFFDQLEALESQSTTSLHHHQQQTPLRPQQNNNNNNNNNNNSSIFSTPPPVTTVMPTLPSSSIPPYTQQINVPSFPNISGDFLSDNSTSSSSSYSTSSDMEMGGGTATTRKKRKRKWKVFFERLMKQVVDKQEELQRKFLEAVEKREHERLVREESWRVQEIARINREHEILAQERSMSAAKDAAVMAFLQKLSEKQPNQPQPQPQPQQVRPSMQLNNNNQQQPPQRSPPPQPPAPLPQPIQAVVSTLDTTKTDNGGDQNMTPAASASSSRWPKVEIEALIKLRTNLDSKYQENGPKGPLWEEISAGMRRLGFNRNSKRCKEKWENINKYFKKVKESNKKRPEDSKTCPYFHQLDALYRERNKFHSNNNIAASSSSSGLVKPDNSVPLMVQPEQQWPPAVTTATTTPAAAQPDQQSQPSEQNFDDEEGTDEEYDDEDEEEENEEEEGGEFELVPSNNNNNKTTNNL
Protein: Phosphoglycerate kinase 1 (EC 2.7.11.1) (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2) (P00558)
Organism: Homo sapiens (Human)
Function: Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:36849569}. Mitochondrion matrix {ECO:0000269|PubMed:26942675, ECO:0000269|PubMed:36849569}. Note=Hypoxic conditions promote mitochondrial targeting (PubMed:26942675). Targeted to the mitochondrion following phosphorylation by MAPK1/ERK2, cis-trans isomerization by PIN1, and binding to mitochondrial circRNA mcPGK1 (PubMed:36849569). {ECO:0000269|PubMed:26942675, ECO:0000269|PubMed:36849569}.
Interaction partners:
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Phosphoglycerate mutase 1
- Alpha-enolase
- Probable phosphoglycerate mutase 4
- Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
- Phosphoglycerate mutase 2
- Bisphosphoglycerate mutase
- Glucose-6-phosphate isomerase
- Fructose-bisphosphate aldolase A
Sequence:
MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI
Protein: Ionotropic receptor 84a (Q9VIA5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- IP13856p
- Ionotropic receptor 25a
- Odorant receptor 47b
- Ionotropic receptor 41a
- Ionotropic receptor 92a
- Ionotropic receptor 76a, isoform E
- Odorant receptor 67d
- Ionotropic receptor 8a
- Ionotropic receptor 21a
- Ionotropic receptor 40a
Sequence:
MIKLQVKVISWPLIILTAFLRVLQIESINTNFLELAAFEDFLRSEHLSHVLVVRGDDADGDWKIECHQKLLANYRVQFYRPEMSANFEDLMFYGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFILGSGRESLPVEQLIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSGGYQKFGNFKNTWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERMFNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVWWCVLALVTGSTILLLFHVRLERMLSNMENRFSFVWFTMLETYLQQGPANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDEAEFCDLQEVMFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPALFALALAMVASALVFLLELFLHWLPDFRRRLGTMST
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Q9C9Z5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 8-B
- NADH dehydrogenase 1 alpha subcomplex subunit 13-A
- NADH dehydrogenase iron-sulfur protein 8-A, mitochondrial
- Transmembrane protein
- NADH dehydrogenase 1 beta subcomplex subunit 3-B
- NADH dehydrogenase 1 beta subcomplex subunit 2
- NADH dehydrogenase 1 beta subcomplex subunit 3-A
- Excitatory amino acid transporter
- At4g16450
- NADH dehydrogenase 1 beta subcomplex subunit 10-A
Sequence:
MSLVWLEAMLPLGIIGGMLCIMGNSQYYIHKAYHGRPKHIGHDEWDVAMERRDKKVVEKAAAPSS
Protein: Spermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase) (Q94BN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- S-adenosylmethionine decarboxylase proenzyme 1
- S-adenosylmethionine decarboxylase proenzyme 3
- S-adenosylmethionine decarboxylase proenzyme 4
- S-adenosylmethionine decarboxylase proenzyme 2
- Probable polyamine oxidase 4
- Polyamine oxidase 3
- Polyamine oxidase 1
- Polyamine oxidase 2
- Probable polyamine oxidase 5
- N-carbamoylputrescine amidase
Sequence:
MEGDVGIGLVCQNTMDGKASNGNGLEKTVPSCCLKAMACVPEDDAKCHSTVVSGWFSEPHPRSGKKGGKAVYFNNPMWPGEAHSLKVEKVLFKDKSDFQEVLVFESATYGKVLVLDGIVQLTEKDECAYQEMIAHLPLCSISSPKNVLVVGGGDGGVLREISRHSSVEVIDICEIDKMVIDVSKKFFPELAVGFDDPRVQLHIGDAAEFLRKSPEGKYDAIIVDSSDPVGPALALVEKPFFETLARALKPGGVLCNMAESMWLHTHLIEDMISICRQTFKSVHYAWSSVPTYPSGVIGFVLCSTEGPAVDFKNPINPIEKLDGAMTHKRELKFYNSDMHRAAFALPTFLRREVASLLAS
Protein: 2,4-diaminopentanoate dehydrogenase (DAPDH) (EC 1.4.1.26) (C1FW05)
Organism: Unknown prokaryotic organism
Function: Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate ((2R,4S)-DAP) to yield 2-amino-4-ketopentanoate (AKP). Although Ord is more efficient with (2R,4S)-DAP, the diastereoisomer (2R,4R)-DAP can also be metabolized. Ord is specific for NAD as hydrogen acceptor.
Interaction partners:
Sequence:
MGKNVKTLIWGFGAMGSGMASILLEKGGYELVSVIDTHPQKAGKDVGELLGRAPLGVKVTMDHLKAFGSHPDVALIATSSFVEEVSPQIEFALENDANVITIAEEMSYPWIDSKEIAERLDALALNRGKTVLGTGINPGFVLDTLVVSLSGVCKEVRHIHAKRVNDLAPFGPTVMRTQGVGTTPEKFEEGIRSGNIVGHIGFRQSIMLIAKALGWTIEDIVEERQPIITNVRRKTNYVDVTPGNVAGCRHTARAYSCGREVIFLEHPQQVCPEAEGVRTGDYVVIDGDPPVNLRIEPEIPGGTGTMAMAVNMIPLVVNAPPGLLTMIDLPVPRSISNGF
Protein: Beta-1,3-glucan-binding protein 2 (BGBP-2) (Beta-1,3-glucan recognition protein 2) (BetaGRP-2) (Q8ISB6)
Organism: Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
Function: Involved in the recognition of invading microorganisms. Binds specifically to beta-1,3-glucan and lipoteichoic acid and causes aggregation of invading microorganisms. Binding to beta-1,3-glucan activates the phenoloxidase cascade.
Subcellular location: Secreted {ECO:0000269|PubMed:14976985}.
Interaction partners:
Sequence:
MWIKSVCLFATIAGCLGQRGGPYKVPDAKLEAIYPKGLRVSVPDDGYSLFAFHGKLNEEMEGLEAGHWSRDITKAKQGRWIFRDRNAELKLGDKIYFWTYVIKDGLGYRQDNGEWTVTEFVNENGTVVDTSTAPPPVAPAVSEEDQSPGPQWRPCERSLTESLARERVCKGSLVFSEDFDGSSLADLGNWTAEVRFPGEPDYPYNLYTTDGTVGFESGSLVVRPVMTESKYHEGIIYDRLDLERCTGQLGTLECRRESSGGQIVPPVMTAKLATRRSFAFKFGRIDIKAKMPRGDWLIPELNLEPLDNIYGNQRYASGLMRVAFVRGNDVYAKKLYGGPIMSDADPFRSMLLKDKQGLANWNNDYHVYSLLWKPNGLELMVDGEVYGTIDAGDGFYQIAKNNLVSHASQWLKGTVMAPFDEKFFITLGLRVAGIHDFTDGPGKPWENKGTKAMINFWNNRFRWFPTWHDTSLKVDYVRVYAL
Protein: LD33778p (Oddjob) (Q9VEF0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- LD20590p
- Uncharacterized protein, isoform C
- Adaptor protein complex 1, mu subunit
- Degringolade, isoform A
- Ankyrin 2, isoform U
- MYND-type zinc finger-containing chromatin reader Zmynd8
- Serendipity locus protein beta
- ADD domain-containing protein 1, isoform A
Sequence:
MSTECRICGERIFTPHPKNIFEKRNHRIRMAIEQITGLEIVLENMLPQHICACCLLDLTQAVAFRQRCLETHANLHQRISSKAGVASKGSPEVSPVLSDPLLKREVLDDTVDTEDDKELLDDDKDLMDDDKDFLEDEKPILRYPPAKKIRIEDQNFPNRQSPRVRVKRLRVPVVEKADSPPPPPREHVRKPRKRRPKPKVDRSIKRYVCDQCGWSFNDHSNMKDHKLRHFEEKFSCDECGRKFYTMPLLRLHIRVHHKGEKPYVCKFCGMGFANSPSRCRHERQMHANELVHPCKICGKRFNSEKGRLKHEEGHKSDQPDVHICLTCNKEFKEAQFLHRHYSTKYHRKRVNLLVNGPKEEFQSEVDPAEFPGYMEEGQAEMEDNQAELDVMLDNIDEEQYEDHEVLQDEDANFEDFEYEEAIPDGEELYT
Protein: Neurotrophic tyrosine kinase, receptor, type 2, isoform CRA_a (cDNA FLJ76753, highly similar to Homo sapiens neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b, mRNA) (Q5VWE5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGFVLFHKIPLDG
Protein: NAC domain-containing protein 86 (NAM-like protein) (No apical meristem-like protein) (Q9FFI5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor directing sieve element enucleation and cytosol degradation. Not required for formation of lytic vacuoles. Regulates, with NAC045, the transcription of NEN1, NEN2, NEN3, NEN4, RTM1, RTM2, UBP16, PLDZETA, ABCB10 and At1g26450.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353}.
Interaction partners:
- Protein NEN4
- Protein BIG GRAIN 1-like A
- Probable glucan endo-1,3-beta-glucosidase BG4
- Heavy metal-associated isoprenylated plant protein 35
Sequence:
MAPVSLPPGFRFHPTDEELITYYLKRKINGQEIELEIIPEVDLYKCEPWDLPGKSLIPSKDQEWFFFSPRDRKYPNGSRTNRATKGGYWKATGKDRRVSWRDRAIGTKKTLVYYRGRAPHGIRTGWVMHEYRLDESECEPSAFGMQDAYALCRVFKKIVIEAKPRDQHQQQHQPYVHTSSNISGSSSFDVCSDLEISSNTPYNTAAHIQPRFGNANAISDHDDWSQYLSQNMPTSFSDYGSPYGPYLTQSKVNTEVQCEMFQHQMSLPPLRVENSQAQTSDFSKRLHQNSGQSGFDDFTFAASNSNQFYNSNVDDHLIHIGNLDEQSYIEEQELILPSFQSNDQDLELYGGSRTNTIDNIEIDDFFSFENQAQDNDNSNVTPNSAGFEMIGEEIIVNHKMLISTRQTTEILYYQVVPSQILKIHINPVHGNEERTMLMEEDSDDSWFQKAENVAKMKLKQISLVAKRYYKCLTIIF
Protein: Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M) (O70250)
Organism: Mus musculus (Mouse)
Function: Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity.
Interaction partners:
- Beta-enolase
- Phosphoglycerate kinase 1
- Phosphoglycerate mutase 1
- Phosphoglycerate kinase 2
- Alpha-enolase
- Gamma-enolase
- Enolase 4
- Glucose-6-phosphate isomerase
- Fructose-bisphosphate aldolase A
- Triosephosphate isomerase
Sequence:
MTTHRLVMVRHGESLWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYTSISKDRRYAGLKPEELPTCESLKDTIARALPFWNEEIAPKIKAGQRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELDQNLKPTKPMRFLGDEETVRKAMEAVAAQGKAK
Protein: Zinc finger protein 386 (Kruppel-like) (Q1WWJ5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MEMEQLTFRDVAVDFSPDEWECLDPPQQRLYRDVMVENYRNLVSVGEDSIPAELPTHCHHFMPFLSKMSAIACAFHKQYKPLSHHCTQNFSPEQILKYSFTEVTNGSYSLQHLYLREDCANVGGNKAAACHGRHKQCLITSNTKDNRNQEQKTALKKPHARTDTFDEPCVYNCKYPQEIFQHDLTLKESWEDLIDRLIFHSSNFIDKELRNRGPISKSDQVESSYPGRAILFSQQIPVSCGQKHNTNDCGLPATDPLLHSQNLDTDIWETPYMYKEISKGFSSGSLLNSCNDVVILEKSGQRDKVQNDFDHCLSPNNHQCNLPKKLFNCDNFFTQCSKLTIQQCNYIQDNHYKSIDCDTMFNKTLNVTRRKIQHSKKSYKCNECGKAFKYCSSYRKHSIIHTGEKPYKCKLCGKSFTQCASLKKHQRIHTGEKPYRCEECGRSFNHYSILGQHQRIHTGEKPYKCKQCGKSFTQCSSLQKHQVIHTGEKPYRCAECGKSFTQNSTLSQHQRIHTGEKPYKCEECGKAFTQCSSLRKHQRIHTGEKPYKCEVCGRAFNCRSSFTKHKRIHTGEKPYKCKDCDKAFIHCTNLIQHQRIHTGEKPYKCNECGKSFSQCSNLRKHERIHT
Protein: Mediator of RNA polymerase II transcription subunit 21 (Q8MNT1)
Organism: Caenorhabditis elegans
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSQRKEVLNQMLDTTLEIFTKSLLESQDLWKMSSHRKLNMDKAAVDAVMARMAKSTQQKVLEKTDQMIKENSVYELFDDMEQLTRESEELNKQLGREMGYNPVNAKRDVALHLSETAEKMLTEADAEIEKIEKELKAEEDEIARRKQVLKELATIVESQQQKL