wanglab/gogpt-training-data huggingface dataset:
Protein: O-fucosyltransferase 1 (O-FucT-1) (EC 2.4.1.-) (O-fucosyltransferase family protein) (Q8W486)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- O-fucosyltransferase 36
- O-fucosyltransferase 23
- Probable xyloglucan galactosyltransferase GT11
- Trimethylguanosine synthase
- Transmembrane protein
- AT5g42660/MJB21_3
- Alkaline ceramidase TOD1
- Transmembrane protein
- At3g26950
- AT3g56750/T8M16_80
Sequence:
MRRLGHHRLHGKTGGVGTKGMVAKLSIGVIVLLICTLSLLFSANIGSNREPTRPSKINVEELWESAKSGGWRPSSAPRSDWPPPTKETNGYLRVRCNGGLNQQRSAICNAVLAARIMNATLVLPELDANSFWHDDSGFQGIYDVEHFIETLKYDVKIVGKIPDVHKNGKTKKIKAFQIRPPRDAPIEWYLTTALKAMREHSAIYLTPFSHRLAEEIDNPEYQRLRCRVNYHALRFKPHIMKLSESIVDKLRSQGHFMSIHLRFEMDMLAFAGCFDIFNPEEQKILRKYRKENFADKRLIYNERRAIGKCPLTPEEVGLILRAMRFDNSTRIYLAAGELFGGEQFMKPFRTLFPRLDNHSSVDPSEELSATSQGLIGSAVDYMVCLLSDIFMPTYDGPSNFANNLLGHRLYYGFRTTIRPDRKALAPIFIAREKGKRAGFEEAVRRVMLKTNFGGPHKRVSPESFYTNSWPECFCQMNPKKSSDKCPPNNVIEILDSRLESIRDPDSTSQTNSTVTGLER
Protein: Protein DESIGUAL 3 (A2RVQ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved, partially redundantly with VCC/DEAL1 and DEAL2, to ensure bilateral symmetry development and early leaf margin patterning, probably via the regulation of auxin and CUC2 distribution.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9ZV57}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MESELGFLVSVVIICADITATVLGIEAEIAQSKAPHHHHQQHSRHSGSGCRRSPSDGAFAEGVAAMVLLFIVHVLANVLGGCTYIRSKQDFKRATANKILAVAFLVLSWIFFVVSYSTLMIGTLANSRTNRLCSLPHRWFFLIGGIFCLGHGVVTSAYYVSAIAAKKEDKENAQQENLANRSRA
Protein: LD32807p (Q5BI37)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00475}.
Interaction partners:
Sequence:
MPICKREGFDLNQKEGKNETFHDNDQVFCCYITKRIFRDYEHYFRHVMVINSTVWQCEATGKENLTYEEAVKSERAARKKMEQFKQSLRAPVLLVVEHAQQSAVNTLNMIVAKFLRKRYFIGEEVSVQAKKNATYTVLGVKLDKNMPEPLNGIYEDTDNLVYRLRPNKGDPSAELDLPFRQLRRSRMEFNLENLSMFIKSNVSRVDGLLRPKPEAYKQYVTDPGVNFSTIFIGKMPRYSPAKIKKPDGKKQSTLNKYIVAGEATAAKSKAKAKSDAKSLAEELERVKREKEAKLIELEKQKAEKKAQLIERVENECNLLLQKTDDLERTDQKVLPRYRQIVTLLPEHLLGDAFMMREFMHTYTGLLSGIEVFRQNLSFYEMTRALTAREIAGPLSDILLVLLGTVFDLQKEEEEECAVTYLDRAAQTQEPYWSMAQAAKSHLYAKRHFSFKVNELPLDALTLSEVLRLHLLGSGAFVNEKAERWRVMYRNGYSSKEDPGLELRLEHSHILRILKNHSVYQLKFKDIMLLIRCLMSQIMTYSGTINLIEERMEQTAKARQDLRALVVGENKRLAAVEINRKKLTQMHHLEVNGVEPEKREALVEKLKKSIAELHAQSDQQHRKHELQMLKLHSQLFNFLVYLGMDRCYRKYYVLESMPGIFVEHSPDSLDTCLEQPITNKSQIEIRQQSALPKNRKDLRVYLLKLYGDDEKKTKKKAKHSLENKENQEHRLNGSAEPMDVESDSPEAPTHFELLMCSGDKRSCIVHDSRNGQRQRWAYIYKAEEIDELIKALNPNGLREYELLQELSVLRSLIEQHAKTCPVDLLSLENETMRKKFMAAMESETNRKYGEANFGLPNGTDLNEVMRLHLVDRIIQFENDIYTGDLGRLKVKDMEKWRSDLLGGNYDAQCKLQWGPGGKLEDEAGSDNESHETHEEDDGALLGKYARKPYRDPGMYLAASADTKPLPDSDDEEDQHTNAVSIPIAVHNMASALLQVEQAIGKRFLKEPYGMKKWDPKQEALKLACDSRLHQWEVSLMESTSFAQVFLHLNILHDCIQWRRSTNKSLCKVCRRGSDPEKMLLCDECNAGTHMFCLKPKLRSVPPGNWYCNDCVKSLGLSNGQNEKDKKQATKKKRKFIVEEEDDEATDEKKKKK
Protein: Ferredoxin (B1P758)
Organism: Zea mays (Maize)
Subcellular location: Plastid, chloroplast {ECO:0000256|ARBA:ARBA00004229, ECO:0000256|RuleBase:RU364001}.
Interaction partners:
- Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- Photosystem I reaction center subunit III
- Photosystem I reaction center subunit III
- Photosystem I reaction center subunit IV A
Sequence:
MATVLSSPRAPAFSFSLRAAPAPTTVAMTRGGGASSRLRAQATYNVKLITPEGEVELQVPDDVYILDYAEEEGIDLPYSCRAGSCSSCAGKVVSGSVDQSDQSYLDDGQIAAGWVLTCVAYPTSDVVIETHKEDDLIS
Protein: ARF GTPase-activating protein GIT1 isoform X2 (G protein-coupled receptor kinase-interacting ArfGAP 1) (E7FAZ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Paxillin
- Paxillin
- Rho guanine nucleotide exchange factor
- Rho guanine nucleotide exchange factor
- G protein-coupled receptor kinase
- G protein-coupled receptor kinase
- G protein-coupled receptor kinase
- G protein-coupled receptor kinase
- Non-specific serine/threonine protein kinase.
- G protein-coupled receptor kinase
Sequence:
MSRKVQRSEVCADCSAPDPGWSSINRGVLICDECCSVHRSLGRHISIVKHLRHSGWPPSLLQMVQTLASNGANSIWEHSLLDPAQVQSGRRKPNPQDKVHPTKSEFIRAKYQMLAFVHKLPCRDDDGVTTKDLSKQLHSSVRTGSLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQVLQAELLVVYGADPGAPDINGRTPIDYARQAGHVELAERLVECQYELTDRLAFYLCGRRPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALNNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSDAKRRQHGKGLTSPTDPLDLSQVDDDQHDYDSVASDEDTDSELTAQNNNNTQRNNRAKSMDSSDLSDGPITLQEYLEVKKALASSEAKVQQLMKVNNNLSEELRRLQKEISRMQTENSALRGAQAGSGATMTGGGVPGHWPDRVRGMGGGGGLSGDSSLIAPSSTPHRRDRQAFSMYEPVGTTSKVLSPALDPLTCRLQPLSPVRKGAPAGPTPYGGAHLSASTDGRYNHPKAGEKYGSGTDSDYDNSQTYDVSIGVGRSSEEDSRGDVDDTEGDPDPTLPCTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALDAVRSSLKLLAASASRLQVECRKAAPSDSSASTVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ
Protein: Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1) (Q5T5C0)
Organism: Homo sapiens (Human)
Function: Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Synapse {ECO:0000250}. Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles (By similarity). {ECO:0000250}.
Interaction partners:
- Syntaxin-1A
- Synaptosomal-associated protein 25
- Syntaxin-3
- Syntaxin-4
- Synaptosomal-associated protein 29
- Syntaxin-7
- Synaptosomal-associated protein 23
- Syntaxin-11
- Syntaxin-binding protein 6
- Alpha-soluble NSF attachment protein
Sequence:
MRKFNIRKVLDGLTAGSSSASQQQQQQHPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDSGAAVIQLQFLINEGALVSALADDTLHLWNLRQKRPAILHSLKFCRERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWNKAIELSSKSHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIWNVRSPAKPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFIILSGGLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSKKEWPINGGNWGLGAQSYPEIIITGHADGSVKFWDASAITLQVLYKLKTSKVFEKSRNKDDRPNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVITEVIPMLEVRLLYEINDVETPEGEQPPPLPTPVGGSNPQPIPPQSHPSTSSSSSDGLRDNVPCLKVKNSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKAVLLNLGTIELYGSNDPYRREPRSPRKSRQPSGAGLCDISEGTVVPEDRCKSPTSGSSSPHNSDDEQKMNNFIEKVKTKSRKFSKMVANDIAKMSRKLSLPTDLKPDLDVKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKTDSSPSPCLWVGTTLGTVLVIALNLPPGGEQRLLQPVIVSPSGTILRLKGAILRMAFLDTTGCLIPPAYEPWREHNVPEEKDEKEKLKKRRPVSVSPSSSQEISENQYAVICSEKQAKVISLPTQNCAYKQNITETSFVLRGDIVALSNSICLACFCANGHIMTFSLPSLRPLLDVYYLPLTNMRIARTFCFTNNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLGDLEERTAAMLSSAESFSKHAHEIMLKYKDKKWYQF
Protein: Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (Slo-alpha) (Slo1) (Slowpoke homolog) (C3VLD3)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLIYFEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRPNRPKSRESRDKQNATRMTRMGQEKKWFTDEPDNAYPRNIQIKPMSTHMANQINQYKSTSSLIPPIREVEDEC
Protein: Polyamine transporter 1 (Q07824)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cell membrane polyamine/proton antiporter, involved in the detoxification of excess polyamines in the cytoplasm. Catalyzes polyamine uptake at alkaline pH and excretion at acidic pH. Recognizes spermidine, spermine and putrescine, the polyamine analogs methylglyoxal bis(guanylhydrazone) (MGBG) and paraquat, the antimalarial drug quinidine, and cycloheximide. Confers resistance to the non-steroidal anti-inflammatory drug indomethacin.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12562762, ECO:0000269|PubMed:13679573, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15637075}; Multi-pass membrane protein {ECO:0000269|PubMed:12562762, ECO:0000269|PubMed:13679573, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15637075}. Note=Enriched on the cell membrane of growing buds.
Interaction partners:
- Quinidine resistance protein 2
- Quinidine resistance protein 1
- Probable transporter AQR1
- Pleiotropic ABC efflux transporter of multiple drugs
- ATP-dependent permease PDR12
- Protein SNQ2
- ATP-dependent permease PDR15
- Polyamine transporter TPO5
- Transcription factor PDR3
Sequence:
MSDHSPISNKENHLLPSDSSRSSSSDMHSTGTTGTTGVEPVDFTGEGAKYTTATEGNGGADLAIQRTTTMNSAAESEVNITRRLTKILTGSVNEPDRVEVDYTNCAPMGGDRPYPPSLPSRDLYEVTFDGPNDPLHPFNWPMKKKVLLCLVLCLDSIAIAMCSSIFASAVPQICEIYHVIEVVAILGITLFVLGFAASPVIYAPLSELYGRKGVLVLSAFGFALFQFAVATAENLQTIFICRFFGGFIGAAPMAVVPAAFADMFDTNVRGKAIALFSLGVFVGPILSPVMGSYIAQRTTWRWLEYVVGCFASAVFVAIVLFFEETHHPTILVNKAKQMRKQSNNWGIHAAHEDVELSIKDIVQKTVTRPIIMLFVEPLLLFVTIYNSFVYGILYLLLEAYPLVFVEGYGFTENGELPYIALIIGMMVCAAFIWYMDNDYLKRCRAKGKLVPEARLYAMVIAGTVFPIGILWFCWTGYYPHKIHWMVPTVGGAFIGFGLMGIFLPCLNYIIESYLLLAASAVAANTFMRSAFGACFPLFAGYMFRGMGIGWAGLLLGLFAAAMIPVPLLFLKYGESIRKKSKYAYAA
Protein: Peptidase inhibitor 16 (PI-16) (Cysteine-rich secretory protein 9) (CRISP-9) (PSP94-binding protein) (CD antigen CD364) (Q6UXB8)
Organism: Homo sapiens (Human)
Function: May inhibit cardiomyocyte growth.
Subcellular location: Secreted {ECO:0000269|PubMed:15344909, ECO:0000269|PubMed:17062675, ECO:0000269|PubMed:22171320}.
Interaction partners:
- Beta-microseminoprotein
- Trifunctional purine biosynthetic protein adenosine-3
Sequence:
MHGSCSFLMLLLPLLLLLVATTGPVGALTDEEKRLMVELHNLYRAQVSPTASDMLHMRWDEELAAFAKAYARQCVWGHNKERGRRGENLFAITDEGMDVPLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHCKNSLCEPIGSPEDAQDLPYLVTEAPSFRATEASDSRKMGTPSSLATGIPAFLVTEVSGSLATKALPAVETQAPTSLATKDPPSMATEAPPCVTTEVPSILAAHSLPSLDEEPVTFPKSTHVPIPKSADKVTDKTKVPSRSPENSLDPKMSLTGARELLPHAQEEAEAEAELPPSSEVLASVFPAQDKPGELQATLDHTGHTSSKSLPNFPNTSATANATGGRALALQSSLPGAEGPDKPSVVSGLNSGPGHVWGPLLGLLLLPPLVLAGIF
Protein: FAS-associated death domain protein (FAS-associating death domain-containing protein) (Q8R2E7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Caspase-8
- Receptor-interacting serine/threonine-protein kinase 1
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- Receptor-interacting serine/threonine-protein kinase 3
- Tumor necrosis factor receptor superfamily member 6
- CASP8 and FADD-like apoptosis regulator
- Tumor necrosis factor ligand superfamily member 6
- TNF receptor-associated factor
- Tumor necrosis factor receptor superfamily member 1A
- Autophagy protein 5
Sequence:
MDPFLVLLHSLSSSLSGNDLTDLKFLCRERVSKRKLERVQSGLDLFSVLLEQNDLERGHTGLLRELLASLGRHDLLQRLDDFEAGATTAATPGEADLRVAFDIVCDNVGRDWKRLARELKVSEAKIDGIEERYPRSLSDRVRETLRVWKNVEKENASVAGLVKALRACRLNLVADLVEEALMAQGSVSKSDDTSSALRDSTVSFSETP
Protein: Developmentally-regulated GTP-binding protein 2 (DRG-2) (Translation factor GTPase DRG2) (TRAFAC GTPase DRG2) (EC 3.6.5.-) (P55039)
Organism: Homo sapiens (Human)
Function: Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
Subcellular location: Nucleus {ECO:0000269|PubMed:29915238}. Cytoplasm {ECO:0000269|PubMed:29915238}.
Interaction partners:
- RWD domain-containing protein 1
- Zinc finger CCCH domain-containing protein 15
- Stalled ribosome sensor GCN1
- RWD domain-containing protein 4
- Large ribosomal subunit protein uL15
- Probable ATP-dependent RNA helicase DDX56
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL2
Sequence:
MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK
Protein: Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.-) (Abnormal cell lineage protein 59) (O44757)
Organism: Caenorhabditis elegans
Function: Probable histone methyltransferase (By similarity). Essential protein required to maintain expression of homeotic genes egl-5 and mab-5. May play an analogous role to the trithorax Group (trxG) proteins. TrxG proteins form multiprotein complexes that are required to maintain the transcriptionally active state of homeotic genes throughout development. May act via a modification of chromatin.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein lin-49
- Mortality factor related protein 1
- Multifunctional procollagen lysine hydroxylase and glycosyltransferase
- Chromo domain-containing protein
- SET domain-containing protein
- Homeobox protein egl-5
- Histone-lysine N-methyltransferase
- Zinc finger protein lsy-27
Sequence:
MHGAGEQQQRYRYNARSDEQHHHPSTSSHQYQQQGARQMHQMHPIQATLMCTPTTTSAAASTSSSGGSNSSGGSGGHRQQGNILRIGNSIKIGDNILEPAGTLVFSQADGTPWTGQRIVVNGSTHAVVKANLFPIGTTPPVLNMQSNQNWYMNQPSGTVPMSSNAPATTSSATPDSGIQSVPTSPPSPSYAMMNDVDIGDHDDEEDDDGPADFTDMPLLKPVDEDDDCYDVPCTSEGPPPNNSNPAITTIPSSCSTPAPPKESLPTGMNVEEWGSFLIASNMDREEIVRRLMAHDPEMAKAIAMRIRELSAEESKKKKDMEAEVSSTTPTTPRARGTRTRNKCATRSTNSPDVTTSNLPEEPSTSTMGLVKENEDVEKVEGKRRGRKPKKRRGFHKESFEDLESDAKKSKAEQHEDHLPEASCSSRPESVIPPPVDPIQFRLKVREMMERKLEQLTQKMSEDMTELRLSHLTSSKMVNGERGKRRESFLRQLNEQSKKLRKGGMLGRKRLRMFMTESDILEENKDNIKKEVKEESTPPPTKLRGRLPSRRTREPSEIVNPEPVEKKFNGEYFEITKSVPSSDDIIPLWMAPSLTCGCTKGACTSDMDCLNRALRVQCSSDCSVPYCSNRRFWKEDCGNKLCVSNGPRSKRVLKTKIARRAGEFLCEYAGEVITREQAQEKFAQDRDPRIIAIAAHLFVDATKRSNIARFIKHSCKPNSRLEVWSVNGFYRAGVFALSDLNPNAEITVDKSDLLPFDMACNCGATECKRVIRGVRWRCADPNEKIVTRRFVIRNRRKTIERSSHSGLPAILQTPMDENSSIRLKMKQVLAAFAFRVRKIDGSMSRTMLPHYTLIIKFLKTKGNNPNPVEFVSLFRKWLEAIDDDDLERAFVAIESHYMSSSILSSSLQSKKAKDNAPRARALSTSCPSPVPSKRGDADLSYLESLYPIGSYDPDDAWESYSTNKKGNAVRCICGALDEEGTMVQCDTCHFWLHVDCCQYVVRSNEKAQKSKNPPSDDGEYICDFCTNKQNGLRPSADVKLTEQPDVRFENCDYYRSLINRRGIQVVLNETVYVNRVLPEDHKAMLRNLREEKKGSKQKDTNKYRFPKAATSPLPIEKVDRKNARIFRVERLFVCPGNNRFVFGSFYAWPHETYADAGRVFSKKEVFATPYYETLPLDEVIGRCLVLDTATWCKGRPKVPKFKEDDVFLCEMQIGKTQRVFEKVPPKNRYPINTNSYVFTEFTHPKKVVRDFRPYDPSNPSPKPPKTSSIPSTSSIDPPQSSSDGLPEVDTKKLSKRHIQRVLKRLVKNGSRRS
Protein: Cyclin-U1-1 (CycU1;1) (Cyclin-P2.1) (CycP2;1) (Q9LJ45)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cyclin-dependent kinase A-1
- ATP-dependent DNA helicase 2 subunit KU80
- DNA ligase 6
- Cyclin-dependent kinase B2-2
- Cyclin-dependent kinase B2-1
- DNA ligase 4
- Cyclin-A3-2
- Protein CELLULOSE SYNTHASE INTERACTIVE 3
- ATP-dependent DNA helicase 2 subunit KU70
- Cyclin-D3-2
Sequence:
MLTAAGDDELDPVVGPESATEAATPRVLTIISHVMEKLVARNEWLAKQTKGFGKSLEAFHGVRAPSISIAKYLERIYKYTKCSPACFVVGYVYIDRLAHKHPGSLVVSLNVHRLLVTCVMIAAKILDDVHYNNEFYARVGGVSNADLNKMELELLFLLDFRVTVSFRVFESYCFHLEKEMQLNDAVSSLKDIQPMQESLSPASTLSSLYV
Protein: ATP-dependent Clp protease ATP-binding subunit CLPT2, chloroplastic (Q8GW78)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Accessory protein regulating the assembly of the plastidial Clp protease system. CLPT1 first binds to the heptameric P-ring containing the CLP3-6 subunits followed by CLPT2, and only then does the P-ring combine with the R-ring composed of the clpP1 and CLPR1-4 subunits. Once the core complex is fully assembled, it then associates to the CLPC chaperone partner to form the functional protease. CLPT2 and CLPT1 are partially redundant.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:14593120, ECO:0000269|PubMed:18431481}.
Interaction partners:
- ATP-dependent Clp protease adapter protein CLPS1
- ATP-dependent Clp protease proteolytic subunit-related protein 1, chloroplastic
- ATP-dependent Clp protease proteolytic subunit 3, chloroplastic
- Chloroplastic ATP-dependent Clp protease proteolytic subunit 1
- ATP-dependent Clp protease proteolytic subunit 6, chloroplastic
- ATP-dependent Clp protease proteolytic subunit-related protein 3, chloroplastic
- ATP-dependent Clp protease proteolytic subunit-related protein 2, chloroplastic
- ATP-dependent Clp protease proteolytic subunit 4, chloroplastic
- ATP-dependent Clp protease proteolytic subunit 5, chloroplastic
- ATP-dependent Clp protease proteolytic subunit-related protein 4, chloroplastic
Sequence:
MAAHSSCNFALTNPIISQIDSFSKKKLSVPLYFFSTRKALTNPWLGVVDSSLSLTSPVSALQTNRPRRIHKSAISSLPTANPDLVVSDAKKPKWSWRAIKSFAMGELEARKLKYPNTGTEALLMGILIEGTSFTSKFLRANKIMLYKVREETVKLLGKADMYFFSPEHPPLTEDAQRALDSALDQNLKAGGIGEVMPAHILLGIWSEVESPGHKILATLGFTDEKSKELESFASESGFLDE
Protein: Large ribosomal subunit protein mL51 (39S ribosomal protein L51, mitochondrial) (A0A087WU28)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MFGVYDNIGILGNFEKHPKELIRGPIWLRGWKGNELQRCIRKRKMVGSRMFADDLHNLNKRIRYLYKHFNRHG
Protein: Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG) (Q6TCH7)
Organism: Homo sapiens (Human)
Function: Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:18547165, ECO:0000269|PubMed:26311497}; Multi-pass membrane protein {ECO:0000269|PubMed:18547165}.
Interaction partners:
- Monocyte to macrophage differentiation factor
- RAF proto-oncogene serine/threonine-protein kinase
- Beclin 1-associated autophagy-related key regulator
Sequence:
MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPGSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVWLNGGIGAPIVQDFAPRVIVMYMIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL
Protein: Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large subunit) (Q54Q71)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Ribonucleoside-diphosphate reductase small subunit
- Ribonucleotide reductase-related
- Thymidylate kinase
- Guanylate kinase
- Nucleoside diphosphate kinase, cytosolic
- Probable nucleoside diphosphate kinase DDB_G0292928
- Nucleoside diphosphate kinase, mitochondrial
- Adenylate kinase isoenzyme 6 homolog
- Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
- UMP-CMP kinase
Sequence:
MISNSINVTPNKESKMYVVKRDGTKENVSFDKITSRISFLCEMEPKLNSDIVDPIEVAQKVVSGVFPGVKTTELDNLAAETAAYMSTRHPDYGILAARISVSNLHKQTSKSFVETVKKQYEFINPKSNLLAPLVSKELYEIVMKHGERLESVIDYYRDFDYDFFGFKTLERSYLHRINGKIVERPQHMLMRVSIGIHGEDLESAINTYKRLSEKLFTHATPTLFNAGTPSPQMSSCFLVQMKEDSIDGIYDTLKQCALISKSAGGIGIAVHKIRAAQSYIRGTNGTSNGLVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADVFEFIDLKKNTGKEEMRARDLFYALWVSDIFMERVEQNGDWALFCPNEAPGLAETHSEEHRALYLKYEATPDLPRRVIKAQELWFAIMESQVETGTPFILYKDACNAKSNQKNLGTISSSNLCTEIIQYTSPDEIAVCNLASIALPKFVRQKVGSTDPKEKEFDHQFLFEITKLITVNLNVIIDRNYYPVAEAKTSNLRHRPIGIGIQGLADVFIKMRMPFDSVAAAKLNVEIAETIYFAALTASHELAIRDGTYESFKGSPASKGILQFDMWNVTPSSRWNWAELKDNIVNKGGLRNSLLIAPMPTASTSQILGNNECFEPYTSNIYSRRVLAGEFTIVNKQLLEDLMELGIWSPEMKNQIVAARGSIQSIGGIPDDLKELYKTVWEIRQRTLIDMAADRGAFIDQSQSFNVFIAEPTFAKLTSMHFYSWKKGLKTGMYYLRTRPAADAIQFTVDPIVSQTPKPVENNINSTTPLKTPTKTPNSSNRISTSPTNNLTSPIRFNITQQQQQQQQQQQQQNNNEDDLANYDGMTCRREEGCLVCGS
Protein: Cystatin-B (RbCyt-B) (Stefin-B) (J7FQE8)
Organism: Oplegnathus fasciatus (Barred knifejaw) (Scaradon fasciatus)
Function: Thiol protease inhibitor. Has papain inhibitory activity in vitro. May be involved in immune responses against invading Gram-negative bacteria.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P04080}.
Interaction partners:
Sequence:
MSMMCGGISAPLDADEDIQKMCDNVKPHAEEKAGKKYDVFTAKTYTTQIVSGTNYFIKIHVGGDDHVHLRVYKKLPCHGGGLELSGMQHSKSLQDPIAYF
Protein: ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (Q5AAW3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).
Subcellular location: Cytoplasm, P-body {ECO:0000250}. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay. {ECO:0000250}.
Interaction partners:
- Decapping enzyme complex catalytic subunit
- Enhancer of mRNA-decapping protein 3
- mRNA-decapping enzyme subunit 1
- mRNA decay factor PAT1 domain-containing protein
- U6 snRNA-associated Sm-like protein LSm1
- Sm-like protein
- Protein SCD6
- CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4
- CCR4-NOT core DEDD family RNase subunit
- General negative regulator of transcription subunit 1
Sequence:
MTDTNWKQNLNLPPKDTRPQTEDVLNTKGKSFEDFNLKRELLMGIFEAGFEKPSPIQEESIPMALAGRDILARAKNGTGKTASFIIPCLQLVKPKLNKVQALILVPTRELALQTSQVVRTLGKHVGTQCMVTTGGTSLRDDIVRLHDPVHILVGTPGRVLDLAARKVVDLSECPLFVMDEADKMLSREFKGIIEQILEFFPPNRQALLFSATFPLAVKSFMDKHLTKPYEINLMDELTLKGISQFYAFVEEKQKLHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGYSCYYSHAKMPQQARNKVFHEFRQGKVRNLVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLMSWNDRYSLYKIEQELGTEIKPIPATIDKSLYVAENADAVPRPFRIDELPKGNETVHNKGYQYKGQPVKDENSGSSSQQQQQPPPQQQQQQSTSPPQQQPQQQQQQPNPQHQFAPHPNGQFPPYPQQFHQPGAIPPQQFNGYPPYPQYPPQFAGYPGQPPQLPQGQQQHAQAQNPAQQY