wanglab/gogpt-training-data huggingface dataset:
Protein: Glutamyl-tRNA(Gln) amidotransferase subunit C (Glu-ADT subunit C) (EC 6.3.5.-) (Q97SE5)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Interaction partners:
Sequence:
MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEVDTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA
Protein: Exopolygalacturonase (EC 3.2.1.67) (Pollen allergen Pla a 2) (allergen Pla a 2.0101) (Q6H9K0)
Organism: Platanus acerifolia (London plane tree)
Function: May function in depolymerizing pectin during pollen development, germination, and tube growth. Acts as an exo-polygalacturonase.
Subcellular location: Secreted {ECO:0000269|Ref.2}. Secreted, cell wall {ECO:0000269|Ref.2}. Golgi apparatus {ECO:0000269|Ref.2}. Endoplasmic reticulum {ECO:0000269|Ref.2}. Vesicle {ECO:0000269|Ref.2}. Note=After 5 minutes in germination medium, detected as a soluble protein and released from apertural and non-apertural regions of pollen grain wall. After 15 and 30 minutes, abundant in the germinal aperture. After 2 hours in germination medium, localization in these regions decreases. In mature, non-hydrated pollen grains, abundant in cisternae and vesicles of Golgi in the apertural region. Sparse in the center of the cytoplasm, associated with cisternae and vesicles of the endoplasmic reticulum (ER) and abundant in the generative cell wall. After 5 minutes of hydration, localization to these regions decreases. After 15 minutes of hydration, present around emergent pollen tube and in the center of the vegetative cell, both in the ER and Golgi. After 30 minutes of hydration, present in juncture between pollen wall and pollen tube. Abundant in the ER cisternae, which show a disorganized and interrupted concentric structure with numerous ER vesicles linked to Golgi vesicles. {ECO:0000269|Ref.2}.
Interaction partners:
Sequence:
RGVQSSGSVFNVNDYGAKGAGDISQAVMKAWKAACASQGPSTVLIPKGNYNMGEVAMQGPCKGSKIGFQIDGVVKAPADPSKFKSDGWVSFYRIDGLTVSGTGTLDGQGQTAWAKNNCDKNPNCKHAAMNLRFDFLKHAMVRDITSLNSKMFHINVLECEDITFQHVTVTAPGTSINTDGIHVGISKGVTITNTKIATGDDCISIGPGSQNVTITQVNCGPGHGISIGSLGRYNNEKEVRGITVKGCTFSGTMNGVRVKTWPNSPPGAATDLTFQDLTMNNVQNPVILDQEYCPYGQCSRQAPSRIKLSNINFNNIRGTSTGKVAVVIACSHGMPCSNMKIGEINLSYRGAGGPATSTCSNVKPTFSGKQVPAIKCA
Protein: RanBD1 domain-containing protein (Q38AA7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- GTP-binding nuclear protein
- Leucine-rich repeat protein
- Nuclear pore protein
- Nucleoporin
- Nuclear pore complex protein
- Nucleoporin
- Nucleoporin NSP1-like C-terminal domain-containing protein
- Small GTP-binding protein RAB6, putative
- Small ubiquitin protein, putative
- Uncharacterized protein
Sequence:
MSDRLRGDRKRGVASDDEDVGDKPAFADAETMAQRRIVRVVRTTPAGPPPSLGGIFKSLPSALPTGTPPLVTKFGSVASGSASSSGISPPPLNGAFPFIPKPTEGAAPAFAMPKVNAMTATDFSSTAAGTITNTGDGNKTDTKPEVGGGLAGTGSLFGGAHSFGNAVNSFVAAKERLAKAAEETDDKGATVDSPVSPTPGDALANADPVSVATGEVVATIPSKLYLFKSDTKSWSDCGVGEAKIKKHESNGGEDKSGGSPKYFYRLIVRDGYALNTPLSKNFILTKSEDTHATFSFPVGTKVVTYLLKYTGANAAECGPAFSKALKETLKLAQEQSK
Protein: Espin (Ectoplasmic specialization protein) (Q63618)
Organism: Rattus norvegicus (Rat)
Function: Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells. Required for the assembly and stabilization of the stereociliary parallel actin bundles. Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia. Involved in the elongation of actin in stereocilia. In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation (By similarity).
Subcellular location: Cytoplasm, cytoskeleton. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q9ET47}. Cell projection, microvillus. Cell junction.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, cytoskeleton. Cell junction. Note=Isoform 1 localizes to parallel actin bundles of ectoplasmic specializations between neighboring Sertoli cells and at sites where Sertoli cells contact the heads of elongate spermatids.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytoskeleton. Cell projection, microvillus. Note=Isoform 2 localizes to parallel actin bundles of brush border microvilli of small intestine and kidney.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine.; SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine.; SUBCELLULAR LOCATION: [Isoform 6]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine.; SUBCELLULAR LOCATION: [Isoform 8]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine.
Interaction partners:
- Myosin-IIIa
- Dihydropyrimidinase-related protein 3
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 2
- Unconventional myosin-VI
- Unconventional myosin-Ia
- Whirlin
- Unconventional myosin-XV
- Actin, cytoplasmic 2
- Unconventional myosin-Ic
Sequence:
MALEQAMQAARRGDLDVLRSLHAAGLLGPSLRDPLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVNWLLYQGGANSAITTDTGALPIHYAAAKGDLPSMKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLADFNGHTHCSRYLRTVQTLSLEHRVLSRDPSMDLEAKQPDSGMSSPNTTMSVQPPNFDLGSPTSTLSNYDSCSSSHSSSKGQRSTRGARSSDLQSYMDMLNPEPRSKQGKPSSLPPPPPPSFPPPPPPGTQLPPPPPGYPAPNPPVGLHLDNIYMQTKNKLRHVEVDSLKKEPSSGDGYSGLRRQDSGLLRQDSELLLRHNTGLRRQDSDRKQRSFSKQPSTGDYYRQLGRSPGEPLAARPGMAHSEEAALLPGNHVHNGCSADSKASRELPPPPPPPPLPEALSSPPPAPPLPIEGAGAACGQRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESPQPAVSPGPSRARSPTPPASGPQPLLNGSIVPAPPATLAPGVHLDVEALIPTLDEQGRPIPEWKRQVMVRKLQQKMQEEEEQRRKEEEEEARLASLPAWRRDILRKKLEEEREQKRKEEERQKLEEIQRAKEQSEKLRTLGYDEAKLAPWQRQVILKKGEIPK
Protein: Kekkon5 (Q86PM1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MILLLLGVLVVLMALPPPTAGTTDWMQSCGTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAISKRLYTPPTDCQEPPQLRGKLWSEVPSENFACRPRILGSVRSFIEANHDNISLPCRIVGSPRPNVTWVYNKRPLQQYDPRVRVLTSVEQMPEQPSQVLTSELRIVGVRASDKGAYTCVADNRGGRAEAEFQLLVSGDYAGAVSASDGMGMGAIGAPTIDPQTNMFLIICLIITTLLLLLLVAVLTLFWYCRRIKTYQKDTTMMSGDGLISSKMDKTHNGSMLEGSVIMEMQKSLLNEVNPVEKPPRRTDIESVDGGDDVLEIKKTLLDDTVYVANHSRDEEAVSVAMSDTTTTPRSRHTYVDDAYANSLPPDLLAFPARVPPTSPSMQSSQSNIPDQVIYGIRSPPSLTSPVYTHMTPHGIYGTKTMTAPHNGFMTLQHPKSRNLALIATTNSSRQHQHHHQLQQQQQHHHHHQQQQQQQQQQQHPLATTSPFLPAPVVYSPATGVVMKQGYMTIPRKPRAPSWAPSTSGAAGHGSIQLSEFQSPTSPNPSETGTATTAELQAEPVYDNLGLRTTAGGNSTLNLTKIAGSQGGAGQQYSMRDRPLPATPSLTSVSSATNASKIYEPIHELIQQQQQLQQQQQQQQQRLGSMDTEPLYGVRQQGITILPGSSISGAGLGHAAYLSPGSGAAVSPSHASSSGDSPKAAKIPPRPPPKPKKKMSVTTTRSGQGSTSQLFDDEGEDGTEV
Protein: Transcription factor VOZ1 (Protein VASCULAR PLANT ONE-ZINC FINGER 1) (AtVOZ1) (Q9SGQ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator acting positively in the phytochrome B signaling pathway. Functions redundantly with VOZ2 to promote flowering downstream of phytochrome B (phyB). Down-regulates 'FLOWERING LOCUS C' (FLC) and up-regulates 'FLOWERING LOCUS T' (FT). Binds to the 38-bp cis-acting region of the AVP1 gene. Interacts with phyB in the cytoplasm and is translocated to the nucleus at signal transmission, where it is subjected to degradation in a phytochrome-dependent manner.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Cytoplasmic in darkness, and translocated to the nucleus depending on the light quality mediated by phytochromes. {ECO:0000250}.
Interaction partners:
- Phytochrome B
- Pyrophosphate-energized vacuolar membrane proton pump 1
- Casein kinase II subunit beta-1
Sequence:
MTGKRSKTNCRSASHKLFKDKAKNRVDDLQGMLLDLQFARKESRPTDVTLLEEQVNQMLREWKSELNEPSPASSLQQGGTLGSFSSDICRLLQLCDEEDDATSKLAAPKPEPADQNLEAGKAAVFQRGYNLVQGKSEHGLPLVDNCKDLSLAAGNNFDGTAPLEYHQQYDLQQEFEPNFNGGFNNCPSYGVVEGPIHISNFIPTICPPPSAFLGPKCALWDCPRPAQGFDWFQDYCSSFHAALAFNEGPPGMNPVVRPGGIGLKDGLLFAALSAKAGGKDVGIPECEGAATAKSPWNAPELFDLTVLESETLREWLFFDKPRRAFESGNRKQRSLPDYNGRGWHESRKQIMVEFGGLKRSYYMDPQPLHHFEWHLYEYEINKCDACALYRLELKLVDGKKTSKGKVSNDSVADLQKQMGRLTAEFPPENNTTNTTNNNKRCIKGRPKVSTKVATGNVQNTVEQANDYGVGEEFNYLVGNLSDYYIP
Protein: Cleavage stimulation factor subunit 2 tau variant (CF-1 64 kDa subunit tau variant) (Cleavage stimulation factor 64 kDa subunit tau variant) (CSTF 64 kDa subunit tau variant) (TauCstF-64) (Q9H0L4)
Organism: Homo sapiens (Human)
Function: May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Cleavage stimulation factor subunit 3
- Cleavage stimulation factor subunit 1
- Cleavage stimulation factor subunit 2
- Pre-mRNA 3'-end-processing factor FIP1
- Symplekin
- Cleavage and polyadenylation specificity factor subunit 3
- Cleavage and polyadenylation specificity factor subunit 2
- Cleavage and polyadenylation specificity factor subunit 1
- pre-mRNA 3' end processing protein WDR33
- Pre-mRNA cleavage complex 2 protein Pcf11
Sequence:
MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS
Protein: Cysteine-rich and transmembrane domain-containing protein WIH2 (Cysteine-rich and transmembrane domain-containing protein A) (Protein WINDHOSE 2) (Q8S8M0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the promotion of megasporogenesis, or promotion of germ cell formation from somatic precursor cells. Acts redundantly with WIH1. Functions in a genetic pathway downstream of SPL/NZZ and WUS and together with TRN2 in promoting megasporogenesis.
Subcellular location: Membrane {ECO:0000269|PubMed:15060130}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 13
- Pollen Ole e 1 allergen and extensin family protein
- Protein SPOROCYTELESS
- Transmembrane protein
- Tetraspanin-16
- Protein WUSCHEL
- Protein TORNADO 2
- Protein TORNADO 1
- Pumilio homolog 12
- Protein DYAD
Sequence:
MSQYNQPPVGVPPPQGYPPEGYPKDAYPPQGYPPQGYPQQGYPPQGYPQQGYPQQGYPPPYAPQYPPPPQHQQQQSSPGFLEGCLAALCCCCLLDACF
Protein: POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4) (Octamer-binding protein 9) (Oct-9) (Octamer-binding transcription factor 9) (OTF-9) (P49335)
Organism: Homo sapiens (Human)
Function: Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
Subcellular location: Nucleus.
Interaction partners:
- Ribose-phosphate pyrophosphokinase 1
- Transcription factor SOX-2
Sequence:
MATAASNPYSILSSTSLVHADSAGMQQGSPFRNPQKLLQSDYLQGVPSNGHPLGHHWVTSLSDGGPWSSTLATSPLDQQDVKPGREDLQLGAIIHHRSPHVAHHSPHTNHPNAWGASPAPNPSITSSGQPLNVYSQPGFTVSGMLEHGGLTPPPAAASAQSLHPVLREPPDHGELGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEGLQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEVYSHTVKTDTSCHDL
Protein: Vacuolar fusion protein MON1 homolog A (Q86VX9)
Organism: Homo sapiens (Human)
Function: Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.
Interaction partners:
- Vacuolar fusion protein CCZ1 homolog B
- Ras-related protein Rab-5A
- Regulator of MON1-CCZ1 complex
- Vacuolar fusion protein MON1 homolog B
- Ras-related protein Rab-7a
- Rab5 GDP/GTP exchange factor
- Vacuolar protein sorting-associated protein 41 homolog
- Vam6/Vps39-like protein
- GTPase-activating protein and VPS9 domain-containing protein 1
- WD repeat and HMG-box DNA-binding protein 1
Sequence:
MHPGGGPSRAERLELGLGRERPAKAIFLHRRPGEGGGRERCLRCGHVCVRRGPGPREAVPSGRPRPDTLTPPWVRQRAVTGTFCASWTPLRNRRAQRMATDMQRKRSSECLDGTLTPSDGQSMERAESPTPGMAQGMEPGAGQEGAMFVHARSYEDLTESEDGAASGDSHKEGTRGPPPLPTDMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPPGAVGRPATEPPREGTTEGDEEDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHADGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDPSFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSILLARNQLVALVRRKDQFLHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALRTPYYSVAQVGIPDLRHFLYKSKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY
Protein: Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) (Q8BP48)
Organism: Mus musculus (Mouse)
Function: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03174}.
Interaction partners:
- Methionine aminopeptidase 2
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein uL5
- mRNA turnover protein 4 homolog
- Ubiquitin-like protein FUBI
Sequence:
MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVCSWTVEGDVNTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDIAAGMIKAGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGDVDEGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSSRPHFMSQF
Protein: Aminodeoxychorismate lyase (EC 4.1.3.38) (Q8IKP7)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MAILIKDNVPSLVELSVQDFIKLGIHGVYTTMKTVMSPEYIFNFSLHMNNLHKYCTNYLKVQENDTNREHISKILKYLTVEDIYKNSSKNIKTGFEYLNNLQNDLKNKHFSDNSNYMVMITLTWDMNSTVDTLEKYYSILCYIKCLPKHQDHVQIDMMCGERKTPNIKYADVFQVRDKFLKLKNENSHEVVLFNESNQITEGLSCNFFCFLNNTLYTAKDELVLKGTIREQIINLCERENIKLKKDFIDIKDIHKFEFSFICSTTRNILPIRKIILFTENRKEPYEMNVNHPILLKLQDKLNQDIENKKEKYETYI
Protein: Uncharacterized protein YPL067C (Q02754)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Putative uncharacterized protein YLR462W
- RHO1 GEF localizing protein 1
Sequence:
MQQDIVNDHQEEAQGWKWEQIKEIIESGELARLKRSRQMTDKYHEHKKRTAGLDMNQYVLQKLGWSLDEPQLENAAAKAFSSSTLYAVRANDFPYNFEPGVVHLVLWSKVALPVHSPDKAVREAARARMNAFLQAQPLLRPLLSSGHVAWFVNYPELQSVARIFHAHVLLFFPRERYSAEQVKTTVDDILSHGFEPLA
Protein: Solute carrier family 25 member 10 (F6RGN5)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Mitochondrial carrier homolog 1
- Mitochondrial carrier homolog 2
Sequence:
MAAEARVSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLYCRWMCHVPVPAPGCAEDSPDELQGGVSGRFPLRRGDSEARASGLLQGPRPSWHPPHPPHRAHFCVSGTATQKLWHQSAILTSRGNGWAARPDTLGSSKESQAQHLLLGPRPPWPWPPVLRSRPLLSPHLLAELLLASSPLSCSCTTPALATRLSRLGTAWPCPSPAGSSSGEQGLPEADFSPLLGQGRGIIPASCPRCPKQHLPALSIEDLGGRVWVQPGCCSPKC
Protein: CXXC-type zinc finger protein 1 (PHD finger and CXXC domain-containing protein 1) (Q9W352)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3. Essential for Set1 association with chromatin and trimethylation of histone H3 at 'Lys-4' at transcription puffs. Additionally, is critical for general chromosomal association of Set1.
Subcellular location: Nucleus {ECO:0000269|PubMed:21694722}.
Interaction partners:
- Retinoblastoma-binding protein 5 homolog
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Histone-lysine N-methyltransferase SETD1
- WD repeat-containing protein 82
- Protein dpy-30 homolog
- Protein will die slowly
- Host cell factor
- Protein dpy-30 homolog
- FI19335p1
Sequence:
MTDKRKYKKTVSFTRCTAIIFLTTKEVSKQKEEIRREIAREFDLPERKSKIATILKQEDQAYCICRSSDCSRFMIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTIFRLVATERAAASNAASTSLNAPGVGPSGAAPAAAPVASATTSQQAPPPTTAAAKRKNSSAREPKMGKRCGTCEGCRRPNCNQCDACRVRVGHKPRCIFRTCVVQAATVLKESQATQAGPSRKREKAAPKSRNVQVGPRAASPEIFLNPELQGIRQCYGPNCCSHARPQSKYCSDKCGFNLATKRIFQVLPQRLQEWNLTPSRAAEETRKHLDNIRHKQSLVRFALAELEKRSEELNMVVERAKRSSIDTLGSQDTADMEDEQSMYCITCGHEIHSRTAIKHMEKCFNKYESQASFGSIFKTRMEGNNMFCDFYNPASKTYCKRLRVLCPEHSKDPKVNDTDVCGSPLVNNVFNPTGEFCRAPKKNCFKHYAWEKIRRAEIDLERVRQWLKMDDLMEQERVMRQQLTSRANLLGLMLHSTYNHEVMDELVRKQQEHLVEFEKQRRRLAHQQQIQTQQKQYQEKQKLMLQQQQQQQQQQQQQQQQQQQQQLQQPQQQQQQQQQQQQEQQQLQLKPHHLQQLQLQLLQQQQKKAQIPQKTQIIYLQKKT
Protein: Phospholipid-transporting ATPase neo1 (EC 7.6.2.1) (Q10309)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endosome membrane {ECO:0000250|UniProtKB:P40527}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized membrane protein C16E9.09c
- Uncharacterized membrane protein C17A5.08
- Meiotically up-regulated gene 165 protein
- Meiotically up-regulated gene 168 protein
- Meiotically up-regulated gene 123 protein
- Endoplasmic reticulum vesicle protein 25
- Meiotically up-regulated gene 166 protein
- Vacuolar calcium ion transporter
Sequence:
MDSRLNRIQSKMKLWIKDKNLSNPSIPLKVLNKSFRSSRQSSVSNGHGLYSLDRDETESLMSSHEASNAGISLDSSFRVIQVGQPEPQYGNNAVTNTKYDLFTFLPKCLYEQFRYFYNMYFLLVSLSQLIPPLKIGYLSTYIAPLIFVLLITLTKEAVDDLKRRRRDSYANNEIYTVNDSPCAAQNIQAGDVVYIAKDQRIPADMILLETTVGNEAFIRTDQLDGETDWKLRIPCSNQHTEGIVHADAPIKSVHHFYGTFTLNNQKRPISVDHTLWANTVLASDGVYGVVVYTGKDTRQSMNSSKAKTKVGLLEKEINFYSKILCTFVLVLSIGLTFSHGIKTDWYISVFRYLILFSSIIPINLRVNLDLAKIVHSKNTESDPNLPGVVVRSSNIPEELGRIEYVLTDKTGTLTQNEMEMKKLHVGTMGFSAESMDVVQACIQNYSTPIPLSEDSKTLVRNLVLALSLCHNVTPSKGHDGVVSYQAASPDEVAIVKWTSTLGLVLTNRTRDAITLNNNVYKILNIFPFKSETKRMGIIVQSPDEKITFYLKGADSIMQNFVKPSFWLEEECGNLAREGLRTLVVAKKDLSAEEYSAFSLAHSDASLSFSNSRDKKMEEIVSRYLENDMDLLGLTGVEDKLQKDVKITLELLRNAGIHVWMLTGDKVETARCIAISSRLVSRGQYIHTINQLSSREEAHNHLLTLRNKPDSCLIIDGESMEFCIGYLQNEFIDIVSDLSSVVICRCTPTQKANMTRLIQEKKQASVCCIGDGGNDVGMIQVANVGIGIVGKEGQQASLAADYSVKEFSHVSRLLLWHGRISYKQTSKLAMFVIHRGLLISVCQVVYSVISAFEPIALFQGLLLVGYSTMYTMLPVFSIVYDRDVSEKLVFLFPELYKEMREQKCFSYKNFISCVLISVYQGLIIQLFTFYLIGFEEEGKMLAVCFSCLIFNELIMVALQINTWEQTIVMSELLTLMMYILSVPFLTNYFELKFLLGLKFYWVSALILFISLLPVWCGKALKRKLKPSSYAKLQR
Protein: Mucolipin TRP cation channel 1 (M0QXD0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTAPAGPRGSETERLLTPNPGYGTQAGPSPAPPTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTGWSMSPSTSG
Protein: AAA-ATPase At5g17760 (EC 3.6.1.-) (Q9FN75)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Ternary complex factor MIP1 leucine-zipper protein
- Putative RRM-containing protein family protein)
- Protein OXIDATIVE STRESS 3 LIKE 3
- At1g28510/F3M18_5
- LIMR family protein At5g01460
- Protein OXIDATIVE STRESS 3 LIKE 4
- ADP-ribosylation factor-like protein 8c
- Protein RALF-like 31
- CASP-like protein 5A2
- Nuclear polyadenylated RNA-binding protein
Sequence:
MFFSKDLPSPTSVFTAYASMAGYMMMIRSMAHELIPAPLQDFIYRTLRSLFFRSSSSTLTLTIDDDNMGMNNEIYRAAQTYLSTKISPDAVRLRISKGHKDKHVNLYLSDGEIVNDVYEDVQLVWRFVTDGGDKKGGGGGVGGRGGGGGRRGGMDDDGKSEYFELSFDKKHKDLILNSYVPYIESKAKEIRDERRILMLHSLNSLRWESVILEHPSTFETMAMEDDLKRDVIEDLDRFIRRKEFYKRVGKAWKRGYLLYGPPGTGKSSLVAAMANYLKFDVYDLQLASVMRDSDLRRLLLATRNRSILVIEDIDCAVDLPNRIEQPVEGKNRGESQGPLTLSGLLNFIDGLWSSCGDERIIIFTTNHKDRLDPALLRPGRMDMHIYMGHCSFQGFKTLASNYLGLSDAAMPHRLFPEIERLIDGEVMTPAQVAEELMKSEDADVALEGLVNVLEKMRLKSKESNPVMMKQKESRLEMEEMRLKSDTEGSPRKNSKRFKKLVLFWT
Protein: ATPase family AAA domain-containing protein 3A (EC 3.6.1.-) (AAA-ATPase TOB3) (Q925I1)
Organism: Mus musculus (Mouse)
Function: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. Involved in mitochondrial-mediated antiviral innate immunity.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9NVI7}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9NVI7}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250|UniProtKB:Q9NVI7}. Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids. Also present at mitochondria-endoplasmic reticulum contact sites; where it interacts with EIF2AK3/PERK. {ECO:0000250|UniProtKB:Q9NVI7}.
Interaction partners:
- Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
- Prohibitin-2
- Single-stranded DNA-binding protein, mitochondrial
- Complex I intermediate-associated protein 30, mitochondrial
- Transcription factor A, mitochondrial
- Translocator protein
- Steroidogenic acute regulatory protein, mitochondrial
Sequence:
MSWLFGIKGPKGEGTGPPLPLPPAQPGAEGGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLTEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLLGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTEGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLKVERPDSQTNKPPHPSLLSC