wanglab/gogpt-training-data huggingface dataset:
Protein: Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1) (O15075)
Organism: Homo sapiens (Human)
Function: Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.
Interaction partners:
- Neuronal migration protein doublecortin
- Neurobeachin
- Calmodulin-like protein 3
- Putative nucleotidyltransferase MAB21L1
- Calmodulin-like protein 6
- Calmodulin-like protein 4
- Calmodulin-like protein 5
- Calmodulin-1
- Transient receptor potential cation channel subfamily M member 5
- Leucine-rich repeat-containing G-protein coupled receptor 5
Sequence:
MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYKAQPAPPELNSESEDYSPSSSETVRSPNSPF
Protein: tRNA(Met) cytidine acetate ligase (EC 6.3.4.-) (Q97P99)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01539}.
Interaction partners:
Sequence:
MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAIVDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRDYQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYAKAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQASKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRYTKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDAMTQKADQIYQLGKPSIAEQNFGRVPIRIETN
Protein: Kappa-casein (Q5ZET1)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
VLSRYPSYGLNYYQQKPVALINNQFLPYPYYAKPAAVRSPAQILQWQVLSNTVPAKSCQAQPTTMARHPHPHLSFMAIPPKKNQDKTEIPTINTIASGEPTSTPTTEAVESTVATLEASPEVIESPPEINTVQVTSTAV
Protein: NEDD8-specific protease 2 (EC 3.4.22.-) (Meiotically up-regulated gene 120 protein) (O13612)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10759889}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- NEDD8-conjugating enzyme ubc12
- NEDD8-activating enzyme E1 catalytic subunit
- Ubiquitin-like protein 1
Sequence:
MRSNSIFTKEIDSEAVKKSSNLRPPSTGSSNSNGSDTASPKKKKKGFFRSLFGSSSSGSKSCGSPFTRIWLEYFEVSLRKNDVDHFRPGYWILDTNIDFFYEIMLRQVLLKRPKEESQQIYLLRPAMVFFLAQAPNPLEIESALPPAMFDASFIFLPINDTNECGIESGSHWSLLVVSVEKGLGWYYDSMSNGNTNDCNLAIKNLGILLKKEFRVRHMKTPQQINDCDCGLHVCENTRILMYRLLQKPYVPKVDMNLDHSVVDSVRLRKALMEVITSLLAAYGSKVPKPSETHTDPEKDKKIFSKICKTEELLELPTLSAVTSDSAQPHSLPASMPSSQPQSRSESLPLTHPNSEPNPKLDSQPNSSPVRRPSLIKVKTASTSVLPTSILQRPPSIVPRPETAAIQHTQQSIEIH
Protein: Adh5p (A0A1D8PS45)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- catechol O-methyltransferase
- Pyruvate decarboxylase
- Pdc12p
- L-iditol 2-dehydrogenase
- Aldehyde dehydrogenase domain-containing protein
- Phosphotransferase
- Phosphotransferase
- Trehalose-phosphatase
- Csh1p
- Ifd6p
Sequence:
MSIPSTQYGFFYNKASGLNLKKDLPVNKPGAGQLLLKVDAVGLCHSDLHVLYEGLDCGDNYVMGHEIAGTVAELGEEVSEFAVGDRVACVGPNGCGLCKHCLTGNDNVCTKSFLDWFGLGYNGGYEQFLLVKRPRNLVKIPDNVTSEEAAAITDAVLTPYHAIKSAGVGPASNILIIGAGGLGGNAIQVAKAFGAKVTVLDKKDKARDQAKAFGADQVYSELPDSVLPGSFSACFDFVSVQATYDLCQKYCEPKGTIVPVGLGATSLNINLADLDLREITVKGSFWGTSMDLREAFELAAQGKVKPNVAHAPLSELPKYMEKLRAGGYEGRVVFNP
Protein: GH11850p (Protamine B) (Q9VJR1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Histone-like protein 18C
- Protamine-like protein 99C
- IP10875p
- MIP05284p
- Testis-enriched HMG-box-containing protein 1
- GEO12017p1
- Testis-enriched HMG-box-containing protein 2, isoform B
- AT26083p
- FACT complex subunit spt16
- AT08725p
Sequence:
MSSNNVNECKSLWNGIISISAKDESPKGLTEMCNHPKRRAPPKCKPMKSCAKPRRKAACAKATRPKVKCAPSQKCSKQGPVTNNAYLNFVRFFRKKHCDLKPQELIAEAAKAWAELPEHRKDRYRRMACKVTTSERHKRRRICK
Protein: Glycogen phosphorylase, liver form (EC 2.4.1.1) (P06737)
Organism: Homo sapiens (Human)
Function: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:22225877}.
Interaction partners:
- 1,4-alpha-glucan-branching enzyme
- Glycogen debranching enzyme
- UTP--glucose-1-phosphate uridylyltransferase
- Glycogen phosphorylase, brain form
- Glycogen [starch] synthase, liver
- Pancreatic alpha-amylase
- Alpha-amylase 2B
- demerged
- Maltase-glucoamylase
- Receptor-interacting serine/threonine-protein kinase 3
Sequence:
MAKPLTDQEKRRQISIRGIVGVENVAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLAELIAEKIGEDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFADYEAYVKCQDKVSQLYMNPKAWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEPSDLKISLSNESNKVNGN
Protein: Large ribosomal subunit protein eL33A (60S ribosomal protein L33-A) (L37) (RP47) (YL37) (P05744)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein eS12
- Large ribosomal subunit protein uL30A
- Small ribosomal subunit protein uS15
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein uL16
- Large ribosomal subunit protein eL29
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein eL36B
- Large ribosomal subunit protein uL6B
- Small ribosomal subunit protein uS5
Sequence:
MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI
Protein: Bifunctional phosphatase IMPL2, chloroplastic (Histidinol-phosphatase) (Histidinol-phosphate phosphatase) (HPP) (EC 3.1.3.15) (Inositol-phosphate phosphatase) (EC 3.1.3.25) (L-galactose 1-phosphate phosphatase) (EC 3.1.3.93) (Protein HISTIDINE BIOSYNTHESIS 7) (Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 2) (Q6NPM8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P).
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:18431481, ECO:0000269|PubMed:20023146}.
Interaction partners:
- Histidinol dehydrogenase, chloroplastic
- Histidinol-phosphate aminotransferase 1, chloroplastic
- L-galactose dehydrogenase
- GDP-L-galactose phosphorylase 2
- GDP-L-galactose phosphorylase 1
- Inositol-3-phosphate synthase isozyme 1
- Probable inositol 3-phosphate synthase isozyme 3
- Inositol-3-phosphate synthase isozyme 2
- 3'
- Probable 3'
Sequence:
MLAQSHFFSKSFDLIPPQSPALRSANPSLRISSSYSNSRLSFLSSSAIAVPVSRRRFCLTMASNSKRPNISNESPSELSDTELDRFAAVGNALADASGEVIRKYFRKKFDIVDKDDMSPVTIADQMAEEAMVSIIFQNLPSHAIYGEEKGWRCKEESADYVWVLDPIDGTKSFITGKPVFGTLIALLYKGKPILGLIDQPILKERWIGMNGRRTKLNGEDISTRSCPKLSQAYLYTTSPHLFSEEAEKAYSRVRDKVKVPLYGCDCYAYALLASGFVDLVIESGLKPYDFLALVPVIEGAGGTITDWTGKRFLWEASSSAVATSFNVVAAGDSDIHQQALESLEWH
Protein: Testis-expressed protein 101 (Lipid raft-associated glycoprotein TEC-21) (Q924B5)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11809740}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:11809740}. Membrane raft {ECO:0000269|PubMed:11809740}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9JMI7}. Secreted {ECO:0000250|UniProtKB:Q9JMI7}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q9JMI7}. Note=Located on plasma membrane of spermatocytes, round and elongated spermatids, and testicular spermatozoa. {ECO:0000250|UniProtKB:Q9JMI7}.
Interaction partners:
- Lymphocyte antigen 6 family member K
- Dipeptidase 3
- Sperm acrosome associated 4
- Pleckstrin homology-like domain, family B, member 3
- Zinc finger protein 575
Sequence:
MGACRIQYILLVFLLIASHWTLVQNIYCEVSRTLSLEDNPSGTFNWTSKAEKCNPGEFCQETVLLIKAEGTKTAILASKSCVPQGAETMTFVQYTAPPGLVAISYSNYCNDSLCNNRNNLASILQAPEPTATSNMSGARHCPTCLALEPCSSAPSMPCANGTTQCYHGKIELSGGGMDSVVHVKGCTTAIGCRLMAKMESVGPMTVKETCSYQSFLHPRMAEIGASWMPTSLWVLELLLPALSLPLIYFP
Protein: Nuclear receptor subfamily 1 group I member 2 (Nuclear receptor subfamily 1, group I, member 2, isoform CRA_c) (H0Y8E2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
LEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
Protein: Chromatin modification-related protein vid21 (Esa1-associated factor vid21) (Vacuolar import and degradation protein 21) (O59773)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00549, ECO:0000269|PubMed:16823372}.
Interaction partners:
- SWR1-complex protein 4
- Histone acetyltransferase mst1
- Enhancer of polycomb-like protein 1
- Chromatin modification-related protein png1
- Actin-related protein 4
- Actin
- NuA4 acetyltransferase complex subunit Tra2
- Chromatin modification-related protein eaf3
- Protein AF-9 homolog
- Probable chromatin modification-related protein eaf7
Sequence:
MKQKETKTSQIALVDGEKLSITDSFASLFTLDEEEENDSVDNEEIKLTKEKHEKLLLLFWLHCKFPNGLEWLHSSSDLLPEQVSEWFNFYQKYRFKRGRNFNLSARESVTPIVEEPIVPEEPDNLEGVSEETPLKETSLELSEEEIITSKSPIPSPETIHKNIDVEEKETIEPTTPVKEVETTAHAEEEKGPLTPDSEYAARQLTEELANKSSQEEGVDKQLRVVEATEKEHEEDGNEENVTVTKPVEVATDQVESKEVKKKEVSETTEPTAPPVTVAEVLEIEDKVPKVDEVEEVHSPEAKVTENDVENVQSGIDIEKTIQLLNNQEIPSEQQIISVDKATESPVQEVAVDVNEKPVDEIVEPSKLQMENKLPSEKSPTIDRTGVEAPLFELSVSMPLTLIPPSKFSEPVKPELSSEAWLLRTEMSPLHLRLKNAHKYVLSDNWSHAYREEIVRQSLHHLTVAKEKGIWSFRQPKRQNEMPRLKTHRDYVLDEMQWMSIDFSQERKWKIILAHRMANWVMDYHQASDKCTVCTPASLSKNKKPYMQENEHQKDSHEETFNEQIVSHFNLNDNNNNKVLSIPRDSLQFYNAVFSDDIFVTTNSEQIQNCVLNVPMYGPPTENNEYCEEISEKYPITPVSRFAYAKTKLKSTCAKASRKRLFNQLELSPPESFMEKKARSDENQLDGNKIKDDNQKLSSVGTFSVRPPYPPSSKDIRPEAPWLPEEDELLLLLLRRYSFNWEFVASRLTPPGLYIPLAEKRTAWDCFERWIQVDPRAANVQLTGSHARLAQQKLDESLRHSDKVSQHLSLRDEGTPNHLIKHNSYFLLPTVSRHYRPITIFEAIRKILKKREFAKKPTMTKRAIAPSAASTEKLPPVPSPLELSRLKSEREAQIQQIQAQRNFAQLQSQNRALRPQNAAVAAGAQQHNQQLAAFQAVAASQNSSNNSSAGVSPIAGRMVPRLQPYAVSSSLKLTPEQIHQLQQRKQTVPTTERTQ
Protein: Hexosyltransferase (EC 2.4.1.-) (Q8VCJ5)
Organism: Mus musculus (Mouse)
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000256|ARBA:ARBA00004447, ECO:0000256|RuleBase:RU364016}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004447, ECO:0000256|RuleBase:RU364016}.
Interaction partners:
Sequence:
EQARYCHGGFGYLLSRSLLLRLRPHLDGCRGDILSARPDEWLGRCLIDTLGIGCVSQHQGQQYRSFELAKNRDPEKEESPAFLSAFAVHPVPEGTLMYRLHKRFSALELERAYSEIEQLQAQIRNLTVLTPEGEAGLSWPVGLPAPFTPHSRFEVLGWDYFTEQHTFACADGAPKCPLQGASRADVGDAVDTALEQLNRRYQPRLRFRKQRLLNGYRRFDPARGMEYTLDLLLEAVTQRGHRRSLARRVSLLRPLSRVEILPMPYVTEATRVQLVLPLLVAEAPAALAFLEAFAASVLEPREHALLTLLLVYGPREGRGGPDPFLGVKAAAAELERRYPGARLAWLAVRAEAPSQVRLMDVISKKHPVDTLFFLTTVWTRPGSEVLNRCRMNAISGWQAFFPVHFQEFNPALSPQRSPPGVPGADPPSPGVDPSRGAPVGGRFDRQASAEGCFYNADYLAARARLAGELAGQEEEEALEGLEVMYVFLRFSGLHLFRAVEPGLVQKFSLRDCSPRLSEELYHRCRLSNLEGLGARTQLAMALFEQEQANST
Protein: Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (Double LIM protein 1) (DLP-1) (P97314)
Organism: Mus musculus (Mouse)
Function: Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESAQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ
Protein: Seven-bladed beta-propeller protein MSMEG_5308 (A0R316)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: Stabilizes the MmpL3/TtfA trehalose monomycolate (TMM) transport complex under stress conditions.
Subcellular location: Cell septum {ECO:0000269|PubMed:31239378}. Cell tip {ECO:0000269|PubMed:31239378}.
Interaction partners:
- Trehalose monomycolate transport factor A
- Cytochrome bc1 complex cytochrome c subunit
- Phenyloxazoline synthase MbtB
Sequence:
MTMAKNILRAITAIVRRDAKTPDTDDSAGSVTFDGALDDLDVAGLVEVGRGPIADIAIDADRETIVVTNSAADCLTVINPYTLAPVGSVRLNGEPFAVAAADDRAYVSVVTAGHDAIKVVDTITGSVLAEYPLAMTVTALAMSPDGKRVFVGRSGHDRIDVAVIDTAAERVGTIDLASGAGAGVDALRVDASGKRLYVATTDPRGSRMVTVNIETAQIESTVWIGAPIRDLALGADGKALVLTSDRQRRGVVHIVDLSTAAVVGAIQIGGAPTQLVLSPDATRAYVVDYDRVIVLCTLTNEILGSIDVGMQPAAVAVRRDGARVYVADYSGQVNAFDVAAELPALYSRLVASEPRQDATTVLPSLQTA
Protein: Caspase-7 (G3IL63)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Interaction partners:
- RING-type E3 ubiquitin transferase
- Caspase-8
- Poly [ADP-ribose] polymerase
- Actin, cytoplasmic 1
- Poly [ADP-ribose] polymerase
- Granzyme B
- Poly [ADP-ribose] polymerase 4
- Centromere protein N
- Apoptotic protease-activating factor 1
- Apoptotic protease-activating factor 1
Sequence:
MADDQNCVAELEKVDPSSEDGVDAKPDRSSIISSILWKKKKNAPPCPVKTTRDRVPTHLYRMDFEKMGKCIIINNKNFDKVTGMDVRNGTDKDAEALFKCFRSLGFDVVVYNDCSCAKMQDLLRKASEEDHSNSACFACVLLSHGEENLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGVQADSGPISETDANPRYKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILDEHGKDLEIMQILTRVNDRVARHFESQCDDPCFNEKKQIPCMVSMLTKELYFGR
Protein: Large ribosomal subunit protein eL39 (60S ribosomal protein L39) (P62891)
Organism: Homo sapiens (Human)
Function: RNA-binding component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23636399}.
Interaction partners:
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL33
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein eL21
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein eS26
- Large ribosomal subunit protein eL20
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein eL38
Sequence:
MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
Protein: E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Q19019)
Organism: Caenorhabditis elegans
Interaction partners:
- Receptor tyrosine-protein kinase let-23
- Sex muscle abnormal protein 5
- Cell death abnormality protein 2
- SH3 domain-containing protein
- Protein vav-1
- Protein nipi-4
- Phosphoinositide 3-kinase adapter subunit
- EHS-1
- ENTH domain-containing protein
- Ubiquitin-ribosomal protein eL40 fusion protein
Sequence:
MGSINTIFHRIHRFVNGTGNNARFVPSTNNSTEALTLSPRAVPSTVSLFEIPSASEMPGFCSEEDRRFLLKACKFMDQVVKSCHSPRLNLKNSPPFILDILPDTYTHLMLIFTQNNDILQDNDYLKIFLESMINKCKEIIKLFKTSAIYNDQSEERRKLTKMSLTFSHMLFEIKALFPEGIYIEDRFRMTKKEAESFWSHHFTKKNIVPWSTFFTALEKHHGSTIGKMEAAELKATIDLSGDDFISNFEFDVFTRLFYPFKTLIKNWQTLTTAHPGYCAFLTYDEVKKRLEKLTKKPGSYIFRLSCTRPGQWAIGYVAPDGKIYQTIPQNKSLIQALHEGHKEGFYIYPNGRDQDINLSKLMDVPQADRVQVTSEQYELYCEMGTTFELCKICDDNEKNIKIEPCGHLLCAKCLANWQDSDGGGNTCPFCRYEIKGTNRVIIDRFKPTPVEIEKAKNVAAAEKKLISLVPDVPPRTYVSQCSQSLLHDASNSIPSVDELPLVPPPLPPKALGTLDTLNSSQTSSSYVNIKELENVETSGEALAQVVNRQRAPSIQAPPLPPRLSASEHQPHHPYTNTNSERE
Protein: DNA-directed RNA polymerase I subunit RPA12 (DNA-directed RNA polymerase I subunit H) (Zinc ribbon domain-containing protein 1) (Q791N7)
Organism: Mus musculus (Mouse)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9P1U0}.
Interaction partners:
- DNA-directed RNA polymerase I subunit RPA49
- DNA-directed RNA polymerases I and III subunit RPAC2
- DNA-directed RNA polymerase I subunit RPA1
- DNA-directed RNA polymerase I subunit RPA2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase I subunit RPA43
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase I subunit RPA34
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
Sequence:
MELARPRSNFQSDLDFCPDCGSVLPLPGIQDTVICSRCGFSIDVRDCEGKVVKTSVVFNKLGATIPLSVDEGPELQGPVIDRRCPRCGHEGMAYHTRQMRSADEGQTVFYTCINCKFQEKEDS
Protein: Protein SOK1 (P40317)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High copy suppressor of a cyclic AMP-dependent protein kinase mutant.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein CUP9
Sequence:
MDQPRTHSGPTTASNPAPSSTNSSSAPSATNSKQERSSSSLSKPSSVVPSKDSPDGDAIAKTQAAALKNDMKSGDTSTLDGSSQNIIPNRASMQKYIDQSSDLLSRSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFLKNDDNEEEIRRNNKVDSIPPKNIYTNINNPSPSPPPSSKQPPSASAPQLPPATEPHKEQAAQQQPPGNASNFLRIFSNKKMRSHSVPTILHSSLRKLSSHNQYYRNQNILLNHPTPSGISKKKFSRNHHQPYLHSNNPLSSNPLSLKRAIFLNQQISGNASTNANNDNINNSTATSMTNQSFLSSSNFDLTLEDRINYIKATPTPVPFPPINLQGLKEIDLQEILKNPQLRHDIIFDPLLQFRPNLDGERGNKKRQLANIYWNDVQNEIYVYSKRPEIFQYNRSRLVPLFDTLRDVLLTIVPQKESPMINNVLDTELNIQELLKGSLIMSNLSGWLADLFKHHCAPMRDPWVDKMSNKFKEAERDSSLTRLIEGLRLVFQILETMKLDIANHQIRILRPALLSNAVEFEKQYFNTLIASKRVNLNTSLLWFDKKFNENVTAGLVRNPSSITIPDVYNICIRSIINLLSCRKMVREYPTPLSFDHARLILLRADIRQIVCILVCRLLFQQLVANDPSMDKATKEYVIHTYSTKRLKNEIISIITDEHGNCRWTKNTMSIAVHLCKVIDDLHREYDNNGSCEQARRPQLPSLDNSKITFAKSWLSKQTQPLSEVYGVLENRVFKSLEDAIFNRSECTIDGRVKQDFVYLYNTNNGNVGSTNTLSTTTDTASVKISPSLMSPSKTSTTTPTGNAIASRGLFAATELEEFENVYRHLYALINLHWSVFGPHYIEMLGDKVNKKGI
Protein: HTH tetR-type domain-containing protein (O33187)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Transport permease protein
- Probable conserved ATP-binding protein ABC transporter
- Uncharacterized protein Rv1545
- Putative 3-methyladenine DNA glycosylase
Sequence:
MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLPSLLLPIWDSELGAGLIATLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELPDDLAP
Protein: Pepsin A-4 (EC 3.4.23.1) (Pepsinogen-4) (P0DJD7)
Organism: Homo sapiens (Human)
Function: Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Subcellular location: Secreted.
Interaction partners:
- Pepsin A-3
- Pepsin A-5
- Vitamin K-dependent protein C
Sequence:
MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA
Protein: Probable transcriptional regulatory protein (Probably TetR-family) (P96900)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable ATP-dependent helicase Lhr
- Endonuclease 8 2 lyase Nei 2)
Sequence:
MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM
Protein: Actin-binding LIM protein 1 (A0A8I6G9J9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSTRVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEATCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQDRQSLGESPRTLSPTPSAEGFQDGRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPDQGINIYRKPPIYKQHAALAAQNKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAIGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKENRERASLLASRYDSPLHSASHAPSSKTSSLPGYGKSGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF