wanglab/gogpt-training-data huggingface dataset:
Protein: Plastid division protein PDV1 (Protein PLASTID DIVISION1) (Q9FK13)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the plastid division machinery. Required to mediate the dissociation of ARC5/DRP5B from plastid outer envelope membranes (OEMs) at the midplastid constriction site in the cytoplasm, thus triggering ARC5/DRP5B ring turnover at the chloroplast division site. Binding to phosphatidylinositol 4-phosphate (PI4P) modulates negatively chloroplast division.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000269|PubMed:16998069, ECO:0000269|PubMed:19453460, ECO:0000269|PubMed:32005784}; Single-pass membrane protein {ECO:0000269|PubMed:16998069, ECO:0000269|PubMed:19453460}. Note=Plastid equatorial positioning in a discontinuous ring mediated by CDP1 (PubMed:16998069, PubMed:19453460). Colocalizes with ARC5/DRP5B at the chloroplast division site (PubMed:32005784). {ECO:0000269|PubMed:16998069, ECO:0000269|PubMed:19453460, ECO:0000269|PubMed:32005784}.
Interaction partners:
- Dynamin-like protein ARC5
- Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic
- Plastid division protein CDP1, chloroplastic
- Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3
- Cell division protein FtsZ homolog 1, chloroplastic
- Protein MULTIPLE CHLOROPLAST DIVISION SITE 1
- Dynamin-related protein 3B
- Septum site-determining protein minD homolog, chloroplastic
- Cell division topological specificity factor homolog, chloroplastic
- Dynamin
Sequence:
MGEMEIEEIEAVLEKIWDLHDKLSDEIHLISKSHFLKSVKPSNRSEKRKNPHGNSGEDKRPGYVFIKGFAVDDNDSTIQEAKSLNAIRTALENLEDQLEFFHTIHTQQRTEKDVAIARLEQSRILLAMRLAEHHGKNYGVLEEALAFVGSIKSNSHYVSPDHLYDSSRNPDGANSIPDGIESNFVINAFASTFGFAKRALGFNHVKGVLGNAAIFAISVVAMLHLHQVATSEHHLQKKEDRFYRSQQRKTYGRDKSSADRSLDHLDVMMARG
Protein: tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (Q9BL15)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nucleolar complex protein 2 homolog
- 26S rRNA
- Pumilio domain-containing protein 12
- Ribosome biogenesis protein BRX1 homolog
- Zinc phosphodiesterase ELAC protein 2 homolog
- Nucleolar GTP-binding protein 1
- tRNA
- Guanine nucleotide-binding protein-like 3 homolog
- Nop domain-containing protein
- RRM domain-containing protein
Sequence:
MVHSSRRKFKSKNKGHEPRENVWRDDRDAPGNQGYRMVEKENEKYWQYYKEQNVFPLEQFDEFRAALQRDLPVSFRFQGCHKDREQLIHEMENRFFGKIMEAGDTAVCVPKSLPWYKEAYQTPMSRTAVRSHPILAQLHNFLVTEAELGNLSRQEAVSMIPPLLLAPTSEHFVLDLCAAPGSKTTQLLEMIHENEENPKGMVIANDVDMKRCYMLIHHTLKRFRTAACAVTCEDAARFPHISDSDGGLIQFDRVLADVICSGDGTLRKNPEIWKKWTPQDGLGLHRMQIAIARKGAQQLKVGGRMVYSTCSMNPIEDEAVVAQLLRDSKGSLKLVDTSSLLPELKRETGVVQWKVFDRDMKLYKSLEDISEEKMKKVIVSSLFPPTEQEAKEMNLHFTMRITPHAQDTGGFFVALIEKVSETSFDPSAANGPAWKKKKMFKDEPFTFLKLDDERWNDIRNHYGVDESFLYQNLFSRRLESNDANSRQLFYANDAVKNFVKENMSKVSIQNAGMKMFSRTEGKVENTRFRLSQEGIRYLFKFMQKQKVKIGTEDMLFMLKSDENLVPLEKLECKGDVRKQQNGTVVVYCDDDEPVCTWVGYHTIAPYISKEERLHLLRMMGVDCAEIELLMKSKRKEKAAQDREAAWARKEEAAKAAEPSSSSTDAPESAETLEIPEENVQEMTE
Protein: Alcohol acyltransferase 16 (AcAT16) (EC 2.3.1.-) (A0A2R6Q326)
Organism: Actinidia chinensis var. chinensis (Chinese soft-hair kiwi)
Function: Involved in the biosynthesis of volatile esters which confer kiwifruit flavor. Alcohol acyl transferase that can use a wide range of alcohols as substrate to produce esters. Exhibits benzoyl-CoA:alcohol O-acyltransferase activity.
Interaction partners:
Sequence:
MASFPPSLVFTVRRNEPTLVLPSKSTPRELKQLSDIDDQEGLRFQVPVIMFYKRKLSMEGEDPVKVIREALAEALVFYYPFAGRLIEGPNRKLMVDCTSEGVLFIEADADIEVNQLIGDTIDPGFSYLDELLHDVPGSEGILGCPLLLIQVTRFRCGGWAFAIRLNHTMSDAPGLVQLLTTIAEFARGAEGAPSVPPVWQREFLAARQPPSITFQHHEYEQVINTTTDDNKSMTHKSFFFGPKEIRAIRSHFPPHYRSVSSTFDVLTACLWRCRTCALGLDPPKTVRISCAANGRGKHDLHVPRGYYGNVFAFPAVVSRAGMISTSSLEYTVEEVKKAKARMTGEYLRSVADLMVTKGRPLYTVAGNYIVSDTTRVGFDAIDFGWGKPVYGGPARAFPLISFYARFKNNRGEDGTVVLICLPEAAMKRFQDELKKMTEEHVDGPFEYKLIKVMSKL
Protein: Pre-mRNA-splicing factor SYF2 (CCNDBP1-interactor) (mp29) (p29) (Q9D198)
Organism: Mus musculus (Mouse)
Function: Involved in pre-mRNA splicing as component of the spliceosome.
Subcellular location: Nucleus {ECO:0000269|PubMed:12437976}.
Interaction partners:
- Pre-mRNA-splicing factor SYF1
- Pre-mRNA-processing factor 17
- Crooked neck-like protein 1
- SNW domain-containing protein 1
- Pleiotropic regulator 1
- 116 kDa U5 small nuclear ribonucleoprotein component
- Protein BUD31 homolog
- Pre-mRNA-splicing factor ISY1 homolog
- Pre-mRNA-processing factor 19
- U2 small nuclear ribonucleoprotein A'
Sequence:
MAAVTEVVVPADGAEARPLAAEELAAQKREQRLRKFRELHLKRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELQEEEKKKECAARGEDYEKVKLLEISAEDAERWERRKKKKNPDLGFSDYAAAQLRQYHRLTKQIKPDMESYERQREKHGEDFFPTSNSLLHGTHVPSSEEIDRMVLDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV
Protein: Interferon, alpha-inducible protein 27-like (Putative ISG12(A) protein) (Q6P9X5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MALSGTGTLVASIASKVASSVAVVKAGGAVSSTILASSQGLNLLAQTALGSGASALGSALGALKAGTVLSSLPASALAVCPIGVKTAVAMLGGAVTVAAVPPVLSAVGFTGSGIAASSLAAKLMSVSAIANGGGVPAGGLVATLQSAGAAGLSMTSKVLVGSTGSAVVASVMGVCKHLYSFL
Protein: GRAS family protein RAM1 (Protein ATYPICAL ARBUSCULE) (Protein REQUIRED FOR ARBUSCULAR MYCORRHIZATION 1) (PhRAM1) (A0A0M4FMK2)
Organism: Petunia hybrida (Petunia)
Function: Transcription factor acting as a central regulator of arbuscular mycorrhiza (AM)-related genes involved at later stages of symbiosis (e.g. VAPYRIN, PT4, PT5, STR, STR2, RAM2, SBT and BCP) but not required for early genes of AM (e.g. common symbiosis signaling genes). Required for the morphogenesis of arbuscules upon symbiosis with AM fungi (e.g. Rhizophagus irregularis, Simiglomus hoi and Acaulospora scrobiculata). Also involved in restricting mycorrhizal colonization of the root meristem.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:G7L166}. Cytoplasm {ECO:0000250|UniProtKB:A0A145P7T2}.
Interaction partners:
Sequence:
MGSLNNEVGSIKCEVGSLKSENSFTKLPSEESLASESKKVTPVSSDFELNCGSLAPTSLSFPAMKFEDDIEIQSPDNSIWESFFADHLEGDFMISSPVRNLPSPQPASSFSSSHNNGNNNNNNYNIYAHRQGIHGQDMMMCSPPRSPLGLYNHPSHKGKGLSPLQKVFNSPNNQFMQIESFNLPALESFLDDDYDKEEDLASSYSTLKVSGTGVAGSSSESFDALSVVPDDLLECLALPSSLSNTSGGFMESLLSDTSAVQVINPDDEIFRTGSIAPLSQQLHQERQQEKQQKQRPVTHARPQQQQIINHNVLVPLAAAPDQEQDSGLQLVHLLLACAEAVSKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTEALSARLAATLATKPSTSALKPFNPFPPNSLEILKIYQILYQACPYVKFAHFTANQAIFEAFEAEERVHIIDLDILQGYQWPAFMQALAARPGGAPFLRITGVGPSPEAVRETGRCLTELAHSLHVPFEFHPVGEQLEDLKPHMFNRRVGEALAVNSVNRLHRVPVNCIGNLLAMIRDQAPNIVTIVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPADSSQRAKLEQYIFAPEIMNIVSCEGPERVVRHERLEKWRRLMEGKGFKGVALSANAVTQSKILLGLYSCDGYKLTEDDGCLLLGWQDRAILAASAWRC
Protein: M53 protein (H2A368)
Organism: Murid herpesvirus 1 (MuHV-1) (Mouse cytomegalovirus)
Interaction partners:
Sequence:
MFRSPEGEERDAAEREEEEGGEARRRSRMMMSPRRVKRARHRPAGSGLRTPLRSPSACRCSSPSPERQWQQRRRAEKRSTTPTDPPPPPKRSAASAAAGAAAPESEYLNVKLSELHDVFQRHPDLEQKYLKIMKLPITGKESIRLPFDFKSHRQHTCLDLSPYGNDQVSRSACTTCKETTRLPTASDSMVAFINQTSNVMKHRKFYFGFRKNMELLKMAANQPQLFQIYYIVQSCVQEIVPLIYYDREMAHMQLIFEKETVHIPSQCIEQILTVAKDAYGVSLDIAHQRITLTARCLRLESSSLRIDVLMLQRKVDELEIPNETNEKFESYSL
Protein: Slow as molasses, isoform B (Slow as molasses, isoform C) (Q9VME5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Rho guanine nucleotide exchange factor 2, isoform D
- Protein nullo
- Disrupted underground network, isoform A
Sequence:
MVLSNSTPNNQSKHNQMVVDTAAMNSDDLSELLQLNAEIEERRRSSRHGDASTACGLLRATMTREELFEISSLDDDRFLTALEYQNSFASPRRVQVTDLDLSSIENLMKYFDEEVPVTPTKTLGTTKAAGNTGKVASTIAKLALQSDPVTPPKPKVGSGHLKISELKQKYEQLPEMETPRSAYQASRKVSASLPMKVKEMAQLFNSKISQVMRRTEEPQYVQLQNEMSPEVKAQNRLVSPLESPVQGPCLVAEEVFRELSVKDKALLFNKFIGDMAAKHPKFTAHAADLKEKVNKQVARGEVVAERQASVKHLAQELEAKCILEPGSPPRPGGVSPPKTTESKTETCTSQLHVSTLTVILKPSPERRAPQPRPRRCLDRQSDEHAREPSQKRNLAAIRTMMPTEAYAPPKKIRRTRQERTGADSQMFFQNEHLETLFYSWLSSENGVQFDITSVSDGQQTIEIATEEGNLLEQPLLEPSTATLEDVSQKSAVERLLEEAIAKLELDNESKKETQVEEKKEMDTAQDPIVQVTPRRIKRQAPPVPAPRPSLSQVTSSASSCKQSEAEESESGLSTLPKITSDESQPETPKDDLQTGEFDFAKPQRPPRKKKMRRTLTWKKENSIVEATAITSTDSDSDYKPPLSGAAKKKSGAICNPLPMPEPSFIELDKSLMRHLNSPRKIKSAYTLTVMSSPSPNADSDQSPSQTPRQSLVQAMRDSFVDQGFETCSNDPMDNSPIRRSSLGATESKPSGFSTPVKGRHASSPAQQQLFSPILIQERPRRSSLAMQVIREDHPLDLDATSSSPSTPCSEREFFANAPTVEIDNSQDESPTGKAHSMFWITSGDFTVSLEIFKNSPERLRLLYEIFTQKSWETRDLAFGIDGHKFIRGAPSSDSVRQSLPERPPSVKGCSHYWFASGDLAVPFSGKLMSSEKIERLFAFLSGEQSELRFGVDHIEFSSVPEFWPTTQKYSIESSYSILVGLQTGASNGLEGRSKYSWPNSSISANQAIKTSDLDQTEFESDSFGNNSGRLSFSPDLFSLDYEAVPLDELFAKAPPSAATPAMSVPQMMQTLKQQQSKLRSVEQRIRGYAKPANLADSSLEHCRNTPQYVHKLRSIIRAIDNIGRDDGFRGCSMEQLESFMYFLSEYADVCLANCSEHMDKILDTLMDRRAVEV
Protein: Thiamine biosynthetic bifunctional enzyme TH1, chloroplastic [Includes: Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase); Hydroxymethylpyrimidine kinase (HMP kinase) (EC 2.7.1.49)] (Q5M731)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential for thiamine biosynthesis. Bifunctional enzyme that catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP and condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:17174261}.
Interaction partners:
- Phosphomethylpyrimidine synthase, chloroplastic
- Hydroxyethylthiazole kinase
- Bifunctional TH2 protein, mitochondrial
- Thiamine thiazole synthase, chloroplastic
- Bifunctional TENA-E protein
- Small ribosomal subunit biogenesis GTPase RsgA 1, mitochondrial
- Thiamine pyrophosphokinase 1
- Thiamine pyrophosphokinase 2
- At5g66005
- DNA polymerase alpha catalytic subunit
Sequence:
MNSLGGIRSWPANWRSTTASMTTTESVRKVPQVLTVAGSDSGAGAGIQADLKVCAARGVYCASVITAVTAQNTRGVQSVHLLPPEFISEQLKSVLSDFEFDVVKTGMLPSTEIVEVLLQNLSDFPVRALVVDPVMVSTSGHVLAGSSILSIFRERLLPIADIITPNVKEASALLDGFRIETVAEMRSAAKSLHEMGPRFVLVKGGDLPDSSDSVDVYFDGKEFHELRSPRIATRNTHGTGCTLASCIAAELAKGSSMLSAVKVAKRFVDNALDYSKDIVIGSGMQGPFDHFFGLKKDPQSSRCSIFNPDDLFLYAVTDSRMNKKWNRSIVDALKAAIEGGATIIQLREKEAETREFLEEAKACIDICRSHGVSLLINDRIDIALACDADGVHVGQSDMPVDLVRSLLGPDKIIGVSCKTPEQAHQAWKDGADYIGSGGVFPTNTKANNRTIGLDGLKEVCEASKLPVVAIGGIGISNAGSVMQIDAPNLKGVAVVSALFDQDCVLTQAKKLHKTLKESKRGI
Protein: Protein DSE3 (Daughter specific expression protein 3) (Q08729)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in the establishment of the daughter fate.
Subcellular location: Bud neck {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Monopolin complex subunit CSM1
- Protein DSE1
- Protein EGT2
- Protein DSE2
- Glucan endo-1,3-beta-D-glucosidase 1
Sequence:
MPRKFLGNKIEKNVDAVRPSSLTLTADDLKYIPPIPQDFEDEDDKVLRTSNGGNRLSKRFGGTLKLKKRLESVPELFLHDFKKRPRSQLEVIREKKFTDMQVPKGPVCPQSTILPLRERKKVKSLPIQRKSLRRPTLSKPAVVQSLGHKTHSDHIIDKVFVSRPAPIVMPVKALTPINPVSLMQTQTQDCCRKNKYGKSGSEILFDEILSAYENVSTSDSTALNSEIDRIIDICASKQIAKKNEAFQVPYVVCPDDTETLFSSTTPKLKPVNSNTLNDVISSPEYTTSGCSTYSDQSNSDEELSEVESIVWNTNKRTMRSSIVSESTSEEGYCTAAETLPSTVSVEDLDIHNKLPKVAQTSSCNTLLNKLSIRKLKKVILDPPKIMHVMTFDDDSDDGDDNDDEDRALNILQKKIDCIEIASCSSSIYSE
Protein: Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like) (P51808)
Organism: Homo sapiens (Human)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity).
Subcellular location: Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Note=Colocalizes with BUB3 at kinetochores specifically during prometaphase.
Interaction partners:
- Cytoplasmic dynein 1 light intermediate chain 1
- Cytoplasmic dynein 1 intermediate chain 2
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic dynein 2 intermediate chain 2
- Cytoplasmic dynein 2 intermediate chain 1
- Dynein light chain 1, cytoplasmic
- Dynein light chain roadblock-type 2
- Dynein light chain roadblock-type 1
- Cytoplasmic dynein 2 light intermediate chain 1
- Dynein light chain 2, cytoplasmic
Sequence:
MEEYHRHCDEVGFNAEEAHNIVKECVDGVLGGEDYNHNNINQWTASIVEQSLTHLVKLGKAYKYIVTCAVVQKSAYGFHTASSCFWDTTSDGTCTVRWENRTMNCIVNVFAIAIVL
Protein: AP-2 complex subunit mu-B (AP-2 mu-B chain) (Clathrin assembly protein complex 2 mu-B medium chain) (Clathrin coat assembly protein AP50-B) (Clathrin coat-associated protein AP50-B) (Mu2-adaptin-B) (Plasma membrane adaptor AP-2 50 kDa protein B) (Q7ZW98)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP50 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositide-containing lipids (By similarity).
Subcellular location: Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane. {ECO:0000250}.
Interaction partners:
- AP complex subunit beta
- AP-2 complex subunit alpha
- AP complex subunit sigma
- Intersectin 2a.
- Clathrin heavy chain
- AP-1 complex subunit gamma.
- Intersectin-2b
- Intersectin 1
- AP complex subunit beta
- EH domain-containing protein 2b
Sequence:
MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHLTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIDKQGKGGTTDDTGKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEYELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMVGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC
Protein: Proteasome (Prosome, macropain) 26S subunit, ATPase, 4, isoform CRA_b (cDNA FLJ78505, highly similar to Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), transcript variant 1, mRNA) (cDNA, FLJ93682, Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4(PSMC4), transcript variant 1, mRNA) (A8K2M0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
Protein: Proteasome 26S subunit, non-ATPase 14 (A0A0G2JZJ1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK
Protein: GTPase HflX (GTP-binding protein HflX) (P25519)
Organism: Escherichia coli (strain K12)
Function: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. In vitro, also exhibits ATPase activity.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00900, ECO:0000269|PubMed:19181811}. Note=May associate with membranes.
Interaction partners:
- Modulator of FtsH protease HflK
- tRNA dimethylallyltransferase
- Large ribosomal subunit protein uL11
- Modulator of FtsH protease HflC
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein bL32
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein bL19
Sequence:
MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENKPNRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI
Protein: Purine nucleoside phosphorylase (PunB) (O26058)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein HP_1531
- Glutamine--fructose-6-phosphate aminotransferase
Sequence:
MLLCAGRNETLKKAVPIGVGLIESAINLTRMCLKNPDTESLIFIGSAGSYSPEMELLSVFESVCGYQIEESFSHLNSYTPLDNFIHIETEEQALFERVRVNSSNYIHTSEMFAKKMVQKGVLLENMEFFSVLSVAKAFSLKAKGIFCVSNYVGLNAYQEFKENHAKVKQILENIIDSLII
Protein: Splicing factor 45 (RNA-binding motif protein 17) (Q5W009)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR031066}.
Interaction partners:
Sequence:
MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEILKCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV
Protein: Oligopeptide transporter (A0A1D8PS46)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Ptr2p
- Ptr22p
Sequence:
MDKIRAVISGGEKPPVDTDNDHNTDFEADRKMPDLDIVVSKSQEFDPVTSHLVNDIMEDEYAAVHVEDDSPYPEVRAAVPSTDDPTLPQNTIRAWVIGLILTTVGCGMNMLFSFHSPSFAITTFVTSILAWPIGNFWAWIVPDWKIFGASLNPGPFNVKEHTIITIMANVSFGTGAAYATDILLAQNMFYKSNFGWGYNLLLIWSTQCIGFAFGGVLRRFVVDSPGAIWPSNLVTATFLTNMHINENHTANGWKISRLAFFVIVFVASFVWYWFPGYIFQALSYFSWITWIKPNNVIINQVFGSSSGLGMIPNNIALDWNQIAGYIGSPLIPPASVIATIFGSIVVIFWIVVPAIHYSNTWYSQYLPISSTGSFDRFQQTYNVSKIIDHKTLSFNEAEYKKYSPLFLSTTFAISYGLSFASILATITHTICFHGRDLIASLKAKEKPDVHNRLMKAYKPVPEWWYLIVFLVFFGMSIATVRAWPTEMPVWGLVFALIIAIIFLLPVAIIYAKTNIAVGLNVVTEFIVGYVLPGRPIAMMLFKTFGYITNNQAVTFVQDMKLGHYMKIDPRTLFWAQFAATIWGSLVQIAVLEWAYGAIDNLCAADQKNHYTCPNGKVFFNASIIWGVIGPQRQFSHGQIYYGLLFFFIIGAVTPVINWLILKKWPNSPVKYLHWPVFFSGTGYIPPATPYNYTSYCAVGLFFGWWIKKKWFHWWSKYNYSLSAGLDIGLAWCSLIIFLCLSLTNTDFPSWWGNDVINTTLDTQVVTNIRHILKEGEAFGPSSW
Protein: Protocadherin 9 (A0A0A6YWY8)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNTSYIYDLIRRTMETPLDRNIGDSGQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQGIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWIKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYGSNEGHFNNGGHMADIPLANLKSYKQAGGTIESPKEHQL
Protein: Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (hLAIR1) (CD antigen CD305) (Q6GTX8)
Organism: Homo sapiens (Human)
Function: Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta. Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells. Inhibits the differentiation of peripheral blood precursors towards dendritic cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10229813, ECO:0000269|PubMed:11160222, ECO:0000269|PubMed:9285412}; Single-pass type I membrane protein {ECO:0000269|PubMed:10229813, ECO:0000269|PubMed:11160222, ECO:0000269|PubMed:9285412}.
Interaction partners:
- Immunoglobulin lambda-like polypeptide 5
- Pulmonary surfactant-associated protein D
- Tyrosine-protein phosphatase non-receptor type 6
- Tyrosine-protein phosphatase non-receptor type 11
- Paired immunoglobulin-like type 2 receptor alpha
- Paired immunoglobulin-like type 2 receptor beta
- Tyrosine-protein kinase CSK
- High affinity immunoglobulin epsilon receptor subunit gamma
- Leukosialin
- NKG2-A/NKG2-B type II integral membrane protein
Sequence:
MSPHPTALLGLVLCLAQTIHTQEEDLPRPSISAEPGTVIPLGSHVTFVCRGPVGVQTFRLERDSRSTYNDTEDVSQASPSESEARFRIDSVREGNAGLYRCIYYKPPKWSEQSDYLELLVKESSGGPDSPDTEPGSSAGPTQRPSDNSHNEHAPASQGLKAEHLYILIGVSVVFLFCLLLLVLFCLHRQNQIKQGPPRSKDEEQKPQQRPDLAVDVLERTADKATVNGLPEKDRETDTSALAAGSSQEVTYAQLDHWALTQRTARAVSPQSTKPMAESITYAAVARH
Protein: Protein Ves (Various environmental stresses-induced protein) (P76214)
Organism: Escherichia coli (strain K12)
Interaction partners:
Sequence:
MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIAANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPFQPFAFAADQVVKAKLTAGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFDGRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
Protein: Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence) (O55126)
Organism: Mus musculus (Mouse)
Function: May act as a positive regulator of L-type calcium channels.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:O75323}. Cytoplasm {ECO:0000305|PubMed:22627147}.
Interaction partners:
- Sequestosome-1
- Microtubule-associated protein 1 light chain 3 beta
Sequence:
MAARVLLARGGLLRPAAQSAFLPGLRTVTSSSHRAREDSWLKSLFVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLDAYNKICQEVLPKIHEGKQYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLKENQEFVNFRKARSDMLLSRKNQLLLEFSFWNEPVPRPGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAIGGFFSQIGQLYMVDHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
Protein: Phospholipid scramblase (I3L3X5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS
Protein: Uncharacterized protein (Q586H9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Amidinotransferase
Sequence:
MRANPIERRKERETALSVRQRELEELRQRKAQLGEELGMELSALEGDNLAAAFPVIQYCGSRPKKDAKKIPVESLGSVMNQFEIAIKAISQNNRDIEQQITDLNRTIGVEAQRFTKLKRHSKELADATGVSLDPNAVQHLAGKSRDGEDCSGGLKELEETTVVLEERKALVEKEIRAARQLVKKKEEAVLAMSSALESRQEEIDQLNRLYNDIRVVDRDIKCEKETLREIISEHDIVDTKLNEAIERNVSRTRLLIEQGINEIKTEIADSVSVSRRGQERVMKAQEFRIDQLEKRLDCINKALKNNHLTRDVEAIVSHKWAAAGDALVAATPDESMYDIEAIIPPQERCHPAIYNLLLTEKERLARRISLLGIIAKEKKEVIDALACKAEALARECQQAIQELDHVASAAAYEEEMQRVEAMEYIQKQRLHYSDLFKEMWKLKTKNQGPLWRAY