wanglab/gogpt-training-data huggingface dataset:
Protein: Gastric inhibitory polypeptide receptor (GIP-R) (Glucose-dependent insulinotropic polypeptide receptor) (P48546)
Organism: Homo sapiens (Human)
Function: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Gastric inhibitory polypeptide
- Pro-glucagon
- Guanine nucleotide-binding protein G
- VIP peptides
- Guanine nucleotide-binding protein G
- Pituitary adenylate cyclase-activating polypeptide
- Pro-opiomelanocortin
- Guanine nucleotide-binding protein G
- Immunoglobulin heavy variable 3-43D
- Follitropin subunit beta
Sequence:
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
Protein: Heat shock protein 110 (Q8IC01)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- non-specific serine/threonine protein kinase
- Heat shock protein DNAJ homologue Pfj4
- GrpE protein homolog
- Heat shock 70 kDa protein
- Heat shock 70 kDa protein
- DnaJ protein, putative
- Thioredoxin-like protein
- DNA-binding chaperone, putative
- Chaperone, putative
- Hsp70-Hsp90 organising protein
Sequence:
MSVLGIDIGNDNSVVATINKGAINVVRNDISERLTPTLVGFTEKERLIGDSALSKLKSNYKNTCRNIKNLIGKIGTDVKDDIEIHEAYGDLIPCEYNYLGYEVEYKNEKVVFSAVRVLSALLSHLIKMAEKYIGKECKEIVLSYPPTFTNCQKECLLAATKIINANVLRIISDNTAVALDYGMYRMKEFKEDNGSLLVFVNIGYANTCVCVARFFSNKCEILCDIADSNLGGRNLDNELIKYITNIFVNNYKMNPLYKNNTPELCPMGTGRLNKFLVTSTASDQQNGINNKVRIKLQEVAIKTKKVLSANNEASIHVECLYEDLDCQGSINRETFEELCSNFFLTKLKHLLDTALCISKVNIQDIHSIEVLGGSTRVPFIQNFLQQYFQKPLSKTLIADESIARGCVLSAAMVSKHYKVKEYECVEKVTHPINVEWHNINDASKSNVEKLYTRDSLKKKVKKIVIPEKGHIKLTAYYENTPDLPSNCIKELGSCIVKINEKNDKIVESHVMTTFSNYDTFTFLGAQTVTKSVIKSKDEKKKADDKTEDKGEKKDAKDQEQNDDKDQTNDNNMNEKDTNDKKEKNNETNSPNKTELKKGEEGKVQTCYTTIPIETLLAQGSYSSKDIFNFSEQEINMQHSDILEGERLKHLNELETIIYESRSRLNGIYKNFVMDDERDRILLSLDDYENWLYDNIEENKNMFIKKKEEIRDLIKNIVQKFDVYNSKQQNLGNIINHLNNIITQCSNKPSDESQNIINRTTKFLNNINSLQEQEKNKPLYEPPVYTLNDIEAEFNEVTQLAQKFFSKLEVEELAKQKAKQEKEKEKEKEKEKEKEKEKNEETNLDANEEQNNEAKNNEEKENSTKNENSANPEE
Protein: histidine kinase (EC 2.7.13.3) (Q89YQ8)
Organism: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
Interaction partners:
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
Sequence:
MPCKPDIMYQRIIAILFFLYASCILSNSAYGKKVNYQQFDNIYLGAEASVVSCFLQDSEGLIWIGSNKGLFSYDGYSTQQHFTYGENNNTRIYCGVIIDNTYLYMGTDNGILVYNYRADRYEQPETDFPTDVRTMALQGDTLWLGALNGLYTYQLQSRKLTSFDTRRNGLPNNTIYSIIRTKDNQIYVGTYNGLCRYIPSNGKFEGIPLPVHSSQSNLFVNSLLEDTTRQCVWIGTEGYLFQYFPSTGQIKQTEAFHNNSIKSLALDGNGDLLAGTDNGLYVYHNDTTPLQHIIHDSRNIQSLTNNIIWNIFADQEHNIWLGTDYGISLSRYNSALQFIPISQITGTGDGNQFYSLFRDSKGFYWFGGANGLIRFTDPAGERHDAIWYRMGDKTYPLSHNRIRHIYEDKEQQLWIATDGSINRYDYATRQFIHYNIVDNTGTYNTNWTYYIFEDTAGQLWISTCLGGIFVVDKHKLMQSTSGQYIAEQNYSVHNGLSGMFINQIIPDNEGNVWVLLYNNKGIDKINPRTREVTKLFADELTGEKSPNYLLCDEDGLLWVGFHGGVMRINPKDESQQSISFGSFSNNEILSMTCVKNSIWVSTTNGLWIIDRKTMDARQQNMTNKRFTSLLFDPKEDCVYLGGADGFGISHSNLEATYQPERPILLTALYINNQLVSPRTRDDVPNIRYTNSIKLKYDQNNLSFELSDLPYSLDEKNKFVYRLEGMDKEWNFLKSNINRITYSNLSYGNYQLIISKLERDGQPSNRPHILNIRILPPWYYTIWAKAIYILLLLSLIAWTINFFRVKNRLKAERREKEKILEQSRQKMAFFTNLSNELKTPLSRIIAPISQLLPSTEEVHEKQTLEEVQRNAMKINSLIHQVLNFNRIEDNKDSLLILSRIELVSFSRSLFSVYEEDKRFTFHFEANKAKIYADMDAIKLGVILDNLLSNAVKFTSEGGSIRLSLFYRQETGLLEICVSDTGAGIPQQDIPYIFQRFFQSPHSGSKEGTGIGLYLVKTYTELHGGSIDGVTSEKGKGTSIGLSIPVIAVEEDEIPVIASKKQLESLPILKPIEAESQDEKFLSNIIRLIEDHLSDADLNVNALCELSGISNKQIYRKIKQLTGMSPVEYIKSIRMKKAAMLLQQKKFTVAEVMYMVGFSNHSYFSKCFQAEFGKTPRQYLNDGL
Protein: Alkyldihydroxyacetonephosphate synthase (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase) (O96759)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
Subcellular location: Peroxisome.
Interaction partners:
- Phospholipid/glycerol acyltransferase domain-containing protein
- SCP2 domain-containing protein
- Electron transfer flavoprotein subunit alpha, mitochondrial
- malate synthase
- isocitrate lyase
- Electron transfer flavoprotein subunit beta
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
Sequence:
MSGEKKEYPKEHIDLYQQIKWNGWGDTRKFLHQLKPSGTIAMTTPEVSSVPLPSLRGFIKKELTLPGEEDKPFVLDETPALQIENIHVDPPKQYPEFVRELKAFFLPDQLKDDKLARITHTFGKSLRDLIRVRIGQVKNAPDLIVLPHSHEEVERLVQLAHKYNVVIIPMGGGSNIVGAIEPVSNERFTVSIDMRRMNKVLWVDRREMTACIQVGIMGPELEKQLHKQGVSLGHDPDSFEFSTLGGWLATCSSGHQSDKYGDIEDMAVSFRTVTPTGTLELRNGARSGAGINYKHIILGSEGTLGIITEAVMKVHAVPQAVEYYGFLFPTFAHAVSALQQIRSSEVIPTMIRVYDPEETQLSFAWKPSKGAVSEFTSAMVKKYLHYIRSFDFKNVCLSIIGFEGPKKVVDFHRTSVFDILSKNAAFGLGSAPGKTWAEKRYDLPYIRDFLLDHNMWVDVAETTVSYANLQTLWKDAKQTFVKHFKDQGIPAWICAHISHTYTNGVCLYFIFASKQNENKDMAQYIEAKKLMTDIIFKYGGSLSHHHGVGYEHVPWMTRYATRGWINVYRSLKETIDPKDICNPRKLIPTIKEENNKEPFLFDVVNVKYPKL
Protein: Threonine dehydratase biosynthetic, chloroplastic (EC 4.3.1.19) (Threonine deaminase) (TD) (Q9ZSS6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia.
Subcellular location: Plastid, chloroplast {ECO:0000250}.
Interaction partners:
- Acetolactate synthase small subunit 1, chloroplastic
- Acetolactate synthase small subunit 2, chloroplastic
- Dihydroxy-acid dehydratase, chloroplastic
- Low-specificity L-threonine aldolase 1
- Probable low-specificity L-threonine aldolase 2
- Acetolactate synthase, chloroplastic
- Threonine synthase 1, chloroplastic
- Threonine synthase 2, chloroplastic
- Branched-chain-amino-acid aminotransferase 1, mitochondrial
- Tryptophan synthase
Sequence:
MNSVQLPTAQSSLRSHIHRPSKPVVGFTHFSSRSRIAVAVLSRDETSMTPPPPKLPLPRLKVSPNSLQYPAGYLGAVPERTNEAENGSIAEAMEYLTNILSTKVYDIAIESPLQLAKKLSKRLGVRMYLKREDLQPVFSFKLRGAYNMMVKLPADQLAKGVICSSAGNHAQGVALSASKLGCTAVIVMPVTTPEIKWQAVENLGATVVLFGDSYDQAQAHAKIRAEEEGLTFIPPFDHPDVIAGQGTVGMEITRQAKGPLHAIFVPVGGGGLIAGIAAYVKRVSPEVKIIGVEPADANAMALSLHHGERVILDQVGGFADGVAVKEVGEETFRISRNLMDGVVLVTRDAICASIKDMFEEKRNILEPAGALALAGAEAYCKYYGLKDVNVVAITSGANMNFDKLRIVTELANVGRQQEAVLATLMPEKPGSFKQFCELVGPMNISEFKYRCSSEKEAVVLYSVGVHTAGELKALQKRMESSQLKTVNLTTSDLVKDHLRYLMGGRSTVGDEVLCRFTFPERPGALMNFLDSFSPRWNITLFHYRGQGETGANVLVGIQVPEQEMEEFKNRAKALGYDYFLVSDDDYFKLLMH
Protein: Tir chaperone (P58233)
Organism: Escherichia coli O157:H7
Function: Chaperone for the type III secretion of Tir. Probably stabilizes the protein, prevents inappropriate protein-proteininteractions and aids in secretion (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Translational regulator CsrA
- Translocated intimin receptor Tir
- Intimin
Sequence:
MSSRSELLLEKFAEKIGIGSISFNENRLCSFAIDEIYYISLSDANDEYMMIYGVCGKFPTDNSNFALEILNANLWFAENGGPYLCYEAGAQSLLLALRFPLDDATPEKLENEIEVVVKSMENLYLVLHNQGITLENEHMKIEEISSSDNKHYYAGR
Protein: BHLH-WRPW transcription factor (Hairy-related 9) (Q9DF41)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- FA complementation group L.
- FA complementation group F.
- FA complementation group G.
- Hairy-related 6.
- FA complementation group D2
- FA complementation group I
- Fanconi anemia, complementation group E.
- Ubiquitin-conjugating enzyme E2 T
- FA core complex-associated protein 100
- Centromere protein S
Sequence:
MPADNMEKQTASPIAGAPASGSHTPDKPKNASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRVQMSAALSADTNVLSKYRAGFNECMNEVTRFLSTCEGVNTEVRSRLLNHLSGCMGQMMAMNYPQPAPAQQAHLAQPLHVQLPSTLPINGASMGSKLSPSEAVSPKVFGGFQLVPATDGQFAFLIPNPAFASATTPVIPLYANASVPVTVNASPVQASSAPTVASPVQGMTSFSGVPQAVSPVGVSAGAESNEPVWRPW
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q5RIL6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Protein salvador homolog 1
- WW domain-containing transcription regulator 1
- Transcriptional coactivator YAP1
- MOB kinase activator 1Ba)
- MOB kinase activator 1A.
- Angiomotin.
- Angiomotin-like 2a
- Serine/threonine-protein kinase 3
- Merlin
- Angiomotin_C domain-containing protein.
Sequence:
MRRAEKPEGYRQMRPKTFPASNNSGNSQQMLQEIRESLRNLSPSSNASKPEQSSGKGPPDESRQQGRSTNPRNSHHHRALQEIRKSLQPFAHDSSSSGDNSSADSSKHTLQTQEPGFDEELMVNRINFQEAVREQIPSARPVNTAIKQAGPPQIQQPLLRRQSWKGSKESLAPQRHSALINDVLIYRPSSPGPQSDLSRPATFPQNLASASSGQRVNAPLSRQVRSITPPPSSWDSNPSTKRYSGNLDYLVPRISPVPQGPRGDGYINPQSQNQRGLSPVPVGRQPIIMQNSNSNKFNFPPSWPQNGSMQNEYMGMNSGARQPPPPPYSMHQTNRQSPTAQQMQSSALTAPPNGASLPQSMLVPNRNSHNLDMYNLGVIRPPVQQAQTPPGQDTSSSWTHSVPGRSNSFTSAPNNRRQCPNSQLSATTVTTVTQAPILQPVKSMRVQKPELHTAVAPAHPPWLQPPPPTAYQEPPTPPAPAAEVPSYQGPPPPYPKHLLQQQQPPPGYDSSPALKPCSKEGDAADNENDTDSTCSSERAEGSEEEKKQITTSPVPVRRHKRDEERKGESRLPMYSPQAFKFFMEQHVENILKNHQQRMRRKKQLESEMQRVGLSGDAQEQMRMMLSQKESNYIRLKRAKMDKCMFEKIKTLGIGAFGEVCLARKVDTGALYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFQEDLAQFYIAELICAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHVRQDSMDFSMEWEDSANCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILYEMVVGQPPFLATTPLETQMKVIRWQTSLHIPLQAKLSPEATDLILKLCRGPDDRLGRNGADEIKAQPFFRTIDFSKDLRQQHQAPYIPKITHSTDTSNFDPVDPDKLWSEDADGNHNDTLTRWFKNGKHPEHAFYEFTFRRFFDDNGHPYSCPKPIESEEEDEDEDYVEEDEPSQRPMEQSRDLVYV
Protein: Lipase E, hormone sensitive type (M0QYP8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MELAGGTEPAEAAMAPASKNAKEGSRSHGRRRWRKDKAKASRLIHNMDLRTMTQSLVTLAEDNIAFFSSQGPGETAQRLSGVFAGVREQALGLEPALGRLLGVAHLFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGR
Protein: Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) (Q9Y5W8)
Organism: Homo sapiens (Human)
Function: May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity). Acts as a GAP for Galphas.
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:11729322}; Peripheral membrane protein {ECO:0000269|PubMed:11729322}; Cytoplasmic side {ECO:0000269|PubMed:11729322}.
Interaction partners:
- Glia-derived nexin
- Sorting nexin-14
Sequence:
MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLTFYILCFVGGGLVVTLLFGKTNSEKYLEQCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKITEKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGDFQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNIGELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDLSNVSSDDSVQLHAYISDTVYADYDPYAVAGVCNDHGKTYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTKMSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDDNIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDAFWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR
Protein: Transport protein particle 20 kDa subunit (TRAPP 20 kDa subunit) (Q9USZ5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the TRAPP I and TRAPP II complexes. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II seems to play a role in intra-Golgi transport (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi apparatus, cis-Golgi network {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Interaction partners:
- Uncharacterized protein C15A10.12c
- Uncharacterized protein C13G6.05c
- Transport protein particle subunit trs120
- Transport protein particle subunit trs31
- Transport protein particle subunit bet3
- Transport protein particle subunit bet5
- Transport protein particle subunit trs23
- Uncharacterized protein CC285.14
- GTP-binding protein ypt1
- Transport protein particle subunit trs85-2
Sequence:
MTAYAAIIGTKDNPVYELEMGPINEKLDRSLNSHLNQFIVHSSLDIVDQLQWTSNAFYMKTIDQFHEMYISAYVTPSNMRFMLLHQNQSADNIKLFFQELHELYIKTLMSPFYQPNQPIRSQAFDLKVRSIARRYL
Protein: Homeotic protein ocelliless (Protein orthodenticle) (P22810)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcriptional regulator involved in pattern formation and cell determination in the embryonic CNS and larval imaginal disks. Also later in development to coordinate the expression of regulatory and structural genes required for photoreceptor cell fate in the ocelli. Has a dual role in the terminal differentiation of subtypes of photoreceptors by regulating rhodopsin (rh) expression: essential for establishing the expression of rh genes in the pale subset of ommatidia as well as repressing Rh6 in outer photoreceptors.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Opsin Rh5
- Opsin Rh6
- Transcription factor btd
- Opsin Rh3
- Protein Optix
- Shaven, isoform A
- Opsin Rh4
Sequence:
MAAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGASSGGLNLGVGVGVGVGVGVGVSQDLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSNPRLLQPGGNITPMDSSSSITTPSPPITPMSPQSAAAAAHAAQSAQSAHHSAAHSAAYMSNHDSYNFWHNQYQQYPNNYAQAPSYYSQMEYFSNQNQVNYNMGHSGYTASNFGLSPSPSFTGTVSAQAFSQNSLDYMSPQDKYANMV
Protein: Complement C8 gamma chain (A0A8I5ZP72)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MWTSGLCFLWHWTVDSDLEQCTPPPPCPITYCHRTAMLSPGAVLFFTLILMASSLGQRTRKPYGSTSPISTIQAQANFNAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHIAPQGAAMAASTFRKLDGICWQVRQLYGITGVPGRFLLQAPRARGPVHVVVAETDYQSFAILYLEQARRLSVKLYTRTLPVSDSALNAFEERVRGANLTEDQIFFFPKYGFCETADQFHILNEMPK
Protein: GH13542p (RasGap protein) (Vacuolar peduncle, isoform A) (Vacuolar peduncle, isoform B) (Vacuolar peduncle, isoform C) (Vacuolar peduncle, isoform D) (Vacuolar peduncle, isoform E) (Vacuolar peduncle, isoform F) (Q8IR23)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Rho GTPase-activating protein 190
- Ras-like protein 1
- Epidermal growth factor receptor
- GTPase-activating protein
- Neurofibromin 1, isoform B
- sphingosine kinase
- Downstream of kinase
- Crossveinless c, isoform C
- Ras GTPase-activating protein raskol
Sequence:
MADLIHLGNIDVVIQKDKPGSPTGCSDDGNLAGLGGMTGLGGIMAPGGIDLGDLAQELDHDEFDGPHMLNGERPAIIAPPESEWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFYIGGRQFISLSDLVGYYTSCSDLLKRERLAIPVAPPEPVNDKKRVVAILPYTKMPETDELSFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVDDLDVSIDPNTVFPWFHPNCTKNEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHSLNHPVVNGIQPEFNQQYVVEKAAEKIYATLRECRDQIGLKKIKGIKHHGHLNKKSDKTTKWKQLYFALINDGSETQLCFYDNPKKTKPKGLIDLSCAYLYQCHDSLWERPYCFQIVERALPCLATVTYLCAPSQESYVEWINSLKAQCDSQLSRAQKKVSRLRELRCLNLHVLEAHRLPFKLVPHPYCSISLNQVKVGKTRVKIAPEPVWEEEFVLDDVPPDVVSLTITLISRGKRGKDSEVAELTIDLSSLKNGQETEGWYQLTGMTPMGEWGSLRLRMRYLDDLIMPCEEYSPLQQLLLESELYAVKALAELCHNDRVPLATALLRVFRQEKRETELIRMLCQAEVTRENETTTLFRGASLATTLMDLYMRTECSGFLQSAVSETVQRILESKQSAELNPTKMDVNDDACTNAEFLLQILDLVTQSIFTSPDACPRNVRFICSCLQKAVMAKWPTERLVRTRVVSGFIFLRLLCPALLNPRQFGLVSETPPMAATRSLVMVAKCLQNLANLIEFGGKEQYMEVVNPFILKNKERMIVFLDQLSSVNDPNQPLGMFVEQSTNLNSQDTGRELATLHHICVSHSQELHELSNILSIKKLVTVTDMLTKHKLKYREMIS
Protein: Photosystem I assembly protein Ycf3 (Q6ENH3)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00439}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00439}.
Interaction partners:
- Photosystem I iron-sulfur center
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I P700 chlorophyll a apoprotein A1
- Photosystem I reaction center subunit II
- NAD
- Photosystem I reaction center subunit III
- Uncharacterized protein
- DNA-directed RNA polymerase subunit beta'
- Photosystem II CP47 reaction center protein
- Cytochrome b6-f complex subunit 4
Sequence:
MPRSRINGNFIDKTFSIVANILLRIIPTTSGEKRAFTYYRDGMLAQSEGNYAEALQNYYEATRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAILQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITKRFEFE
Protein: AP2-like ethylene-responsive transcription factor SMZ (Protein SCHLAFMUTZE) (Q6PV68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Repressor of flowering.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- 1-aminocyclopropane-1-carboxylate oxidase 4
- Squamosa promoter-binding-like protein 9
- MADS-box protein SOC1
- Squamosa promoter-binding-like protein 15
- Squamosa promoter-binding-like protein 3
- Squamosa promoter-binding-like protein 10
- Agamous-like MADS-box protein AGL8
- Squamosa promoter-binding-like protein 5
- Protein LEAFY
- Squamosa promoter-binding-like protein 13A
Sequence:
MLDLNLKIFSSYNEDQDRKVPLMISTTGEEESNSSSSSTTDSAARDAFIAFGILKRDDDLVPPPPPPPHKETGDLFPVVADARRNIEFSVEDSHWLNLSSLQRNTQKMVKKSRRGPRSRSSQYRGVTFYRRTGRWESHIWDCGKQVYLGGFDTAYAAARAYDRAAIKFRGLDADINFVVDDYRHDIDKMKNLNKVEFVQTLRRESASFGRGSSKYKGLALQKCTQFKTHDQIHLFQNRGWDAAAIKYNELGKGEGAMKFGAHIKGNGHNDLELSLGISSSSESIKLTTGDYYKGINRSTMGLYGKQSSIFLPMATMKPLKTVAASSGFPFISMTSSSSSMSNCFDP
Protein: Transcription elongation factor 1 homolog (Q4GZ51)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSSSKGGETNNAAGADASSPQLSRNSRTFLRTKLQKRAKKNSNEGKGDSSGGAKFQKRSLQCLKKFTCPVCRMKGAVRIDVNAKEQQAVVSCSYCMQLKPRPVDLPYPFTTSFLPKLQNRADVFFEFNELYRRLQLQANSIECAGEDVSGLNTSHLLRDGVLGLTGLATGGVTNENNECEEGNDYEEGGDYEEDASDDDETVAIGCGNEATVNVAEEETVTSDVAVDDVNAFFDESD
Protein: Tubulin beta chain (K7ESM5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSCQTGAGNNWAKGHYTEGAELVDAVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMMAACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQ
Protein: Meiosis-specific protein MEI4 (P29467)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for meiotic induction of recombination, viable spore production and chromosome synapsis. Component of the MER2-MEI4-REC114 complex which seems to be required for meiotic double-strand break (DSB) formation.
Subcellular location: Nucleus {ECO:0000269|PubMed:16783010}. Chromosome {ECO:0000269|PubMed:16783010}. Note=Localizes to chromosomes.
Interaction partners:
- Meiotic recombination protein REC114
- Recombination protein 107
- Meiotic recombination protein REC104
- Meiotic recombination protein REC102
- Meiosis-specific protein SPO11
- Protein RED1
- Meiotic recombination 1 protein
- Antiviral protein SKI8
- Meiosis-specific protein HOP1
Sequence:
MSRGKLEDMEQKETSEVDWIICFALIQSRNPTLWKRALSRKKGDVEDVGALKSEKNLKINPRENSKHIYKWVAPFENGFLNNKSLFAHLEPIYNFLCQNKYKSFEDAVGLKELQSFSKDVSTADINNWFLPRYKILLKILSLKTKEIDFRGLSQVFQTLQILLVSHYSHRIDSDSSFKRTLIDVHVFNFIAKFLFNRILLKKNQNDPKWLQNFYDQGDGKHLCDKVDYKRLCSLHFTLIYSIINIQLIKIKTNQTFEPQILKYVSVLKLIEHILIIIESLIHVLIRFVSKHKLICINRKKAYCRVYLERELSLKKTYLKNFYSVISGVPEKELGGLLKILKIVILSLLETFESIEWQHLKPFLEKFPAHEISLQKKRKYIQAALLITAERNLIARFRLSRWFNETENI
Protein: Cell division cycle protein CDT1 (SIC1 indispensable protein 2) (Topoisomerase-A hypersensitive protein 11) (P47112)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA replication licensing factor, required for pre-replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation. Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication. Required for the recruitment of the MCM2-7 helicase complex to the replication origins.
Subcellular location: Cytoplasm. Nucleus. Note=Undergoes cell cycle-dependent changes in its nuclear localization. Exits the nucleus and remains in the cytoplasm during S phase through early mitosis, and re-accumulates in the nucleus around the end of mitosis.
Interaction partners:
- DNA replication licensing factor MCM2
- Nucleolar complex-associated protein 3
- Origin recognition complex subunit 6
- DNA replication licensing factor MCM3
- Origin recognition complex subunit 3
- Minichromosome maintenance protein 5
- Origin recognition complex subunit 1
- Origin recognition complex subunit 5
- DNA replication licensing factor MCM6
- Pre-rRNA-processing protein IPI3
Sequence:
MSGTANSRRKEVLRVPVIDLNRVSDEEQLLPVVRAILLQHDTFLLKNYANKAVLDALLAGLTTKDLPDTSQGFDANFTGTLPLEDDVWLEQYIFDTDPQLRFDRKCRNESLCSIYSRLFKLGLFFAQLCVKSVVSSAELQDCISTSHYATKLTRYFNDNGSTHDGADAGATVLPTGDDFQYLFERDYVTFLPTGVLTIFPCAKAIRYKPSTMATTDNSWVSIDEPDCLLFHTGTLLARWSQGMHTTSPLQIDPRANIVSLTIWPPLTTPISSKGEGTIANHLLEQQIKAFPKVAQQYYPRELSILRLQDAMKFVKELFTVCETVLSLNALSRSTGVPPELHVLLPQISSMMKRKIVQDDILKLLTIWSDAYVVELNSRGELTMNLPKRDNLTTLTNKSRTLAFVERAESWYQQVIASKDEIMTDVPAFKINKRRSSSNSKTVLSSKVQTKSSNANALNNSRYLANSKENFMYKEKMPDSQANLMDRLRERERRSAALLSQRQKRYQQFLAMKMTQVFDILFSLTRGQPYTETYLSSLIVDSLQDSNNPIGTKEASEILAGLQGILPMDISVHQVDGGLKVYRWNSLDKNRFSKLLQIHKSKQQD
Protein: Transcriptional co-activator (Hfi1/Ada1), putative (AFU_orthologue AFUA_2G06060) (C8VBC1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 6
- SAGA-like transcriptional regulatory complex subunit Spt3, putative
- Transcriptional activator spt7
- Transcription initiation factor TFIID subunit 10
- Transcriptional regulator Ngg1, putative
- Transcription initiation factor TFIID subunit 5
- Transcriptional adapter 2
- WD repeat protein
Sequence:
MQQIDLAALNRAAEDSASAVPPSRNAAPTQKSKALISVSRLDLGPPYLELKSRIGANWAEYKEAITLFLLGQLNQDELSSRIDPIICADPKTEHLHNNFICAIIANLTRDLPDHGVASWVSANDKPSVVSKPTSGDAAEQRLKTEVMQLPPRDRRRIKAIPERDPHDAVRNELEEYHLAKQIKLPSQVPASAGGLNMTNWELEVRKRYVQPLASETGEFPDAESIHARMTPICYEESVVNGAGVACAEFMAIATETFVKEVLSVVFSRTRCNGPSGTINGMMKRSYKQQLEREELAFTRGEIAKDGATGLLPVEAKEARTRSALGVRDLRLSLELGSGVLSHMPLLVDQIMGGYFEDELEADRRGRTDTNGTEPTDMDEMDVDEADWGWEGATAGDHQQLGTLLDECLAMAS