wanglab/gogpt-training-data huggingface dataset:
Protein: AT01533p (Q9VKM7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
- RE14391p
Sequence:
MSEQWEVVSKSRKQKNLDKKVSAHNEQKRIAAQLPKLEELLPTQRYRNLFGSSNNNNSKSHSPAKSSSSASSSSKANKSPVKKHTAKNASTQKRTTSAAASKPKTLELALRNITRDDFAAQLEQVKLSCPGSELRWLSHIALYFNEALSYDCDPIFSGRSAQYPSNLASASLKYSIVEFLGSVGEQNLEYFFYSLLDSMSTDLNNNQTVAGYKLILQLIGQNWPNICSRNLAKTALLRNSYQNRSNICLSILWAIGQGGYQSLNEGVRVWQNLMLPNLELKQYTKFVVEYMERALSAAAVRKTADPLQINQQEFFATYNALNAPYNHLPKEWQQSLKRSARLLLQHYINSPVRHANIFLTLFREISAGSKQTNEIEGCISCLLSSGRDDCLRVWRMNYKKQQLPSLLLLKAINDNWTTSTHELATSTVYHSFLQDVANLNEELQGSKRNEGHLDDLKEVLLSVQEKSSAQQKKNKQKAAAEKKKCGCCKWTLGSIFIIALIAGALYYDTEVNGKGVFEKSATGKVLKNAGVLPHVQKSWYTVMGAGARGYKWAEVNVPPYAEPVIKTTCDLWKLARNAACNAYQNGKGYFGAKWPVVAKFIDQYVPNSSGKIEAFAAGVSDLAASSYEKAAALIKEKVLVGRLSPENINQALNQTRNAALEYYNQFHKKVDAYAKLK
Protein: Sulfotransferase 1C2A (ST1C2A) (rSULT1C2A) (EC 2.8.2.1) (Sulfotransferase K2) (Q9WUW9)
Organism: Rattus norvegicus (Rat)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Sulfonates p-nitrophenol, a small phenolic compond. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O46503}. Lysosome {ECO:0000269|PubMed:10872834}. Mitochondrion {ECO:0000250|UniProtKB:Q9WUW8}.
Interaction partners:
Sequence:
MALAPELSRQTKLKEVAGIPLMDPTVNNWSQIQTFKAKPDDLLICTYPKSGTTWIQEIVNMIEQNGDVEKCQRTIIQHRHPVIEWARPPQPSGVDKANAMPAPRILRTHLPPQLLPPSFWTNNCKYLYVARNAKDCMVSYYHFYRMCQVLPNPGTWNEYFETFINGKVSWGSWFDHVKGWWEIRDRYQILFLFYEDMKRDPKREIQKVMQFMGKNLDEEVVDKIVLETSFEKMKDNPLTNFSTIPKTIMDQSISPFMRKGIVGDWKNHFTVAQNERFDEIYEQKMDGTSLNFCMEL
Protein: Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein) (O60296)
Organism: Homo sapiens (Human)
Function: May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Subcellular location: Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity). {ECO:0000250}.
Interaction partners:
- Mitochondrial Rho GTPase 1
- Mitochondrial Rho GTPase 2
- Gamma-aminobutyric acid receptor subunit beta-2
- Trafficking kinesin-binding protein 1
- Gamma-aminobutyric acid receptor subunit alpha-1
- STE20-related kinase adapter protein beta
- Kinesin heavy chain isoform 5C
- Gamma-aminobutyric acid receptor subunit delta
- Gamma-aminobutyric acid receptor subunit alpha-5
- Gamma-aminobutyric acid receptor subunit alpha-3
Sequence:
MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQSEITDLSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLPGDAIYHISDLEEDEEEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANPGKCLSCTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGSSGSSSSNTAVNSPALSYRLSIGESITNRRDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQPLPKSLAIPSTPPNSPSHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKRLGIARVVKNPGAQENGRCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAPVCTSSPKMGVLKED
Protein: CagY protein (A7WPC5)
Organism: Helicobacter pylori (Campylobacter pylori)
Interaction partners:
Sequence:
DCVSKARNEKEKKECEKLLTPEARKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESVKAYKDCVSQAKNEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKNEAEKKECEKLLTPEARKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNAKTDEERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEEAKKSVKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSRARNEKEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKNEAEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDLQKKVLAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEAKKSVKAYLDCVSQAKNEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSKARNEKEKKECEKLLTPEARKFLAKQVLNCLEKAGNEEERKACLKNLPKDLQENVLAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRA
Protein: Plasma serine protease inhibitor (Plasminogen activator inhibitor 3) (PAI-3) (PAI3) (Protein C inhibitor) (PCI) (Serpin A5) (P70458)
Organism: Mus musculus (Mouse)
Function: Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and pro-inflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin complex. Acts as an anticoagulant factor by inhibiting blood coagulation factors like prothrombin, factor XI, factor Xa, plasma kallikrein and fibrinolytic enzymes such as tissue- and urinary-type plasminogen activators. In seminal plasma, inactivates several serine proteases implicated in the reproductive system. Inhibits the serpin acrosin; indirectly protects component of the male genital tract from being degraded by excessive released acrosin. Inhibits tissue- and urinary-type plasminogen activator, prostate-specific antigen and kallikrein activities; has a control on the sperm motility and fertilization. Inhibits the activated protein C-catalyzed degradation of SEMG1 and SEMG2; regulates the degradation of semenogelin during the process of transfer of spermatozoa from the male reproductive tract into the female tract. In urine, inhibits urinary-type plasminogen activator and kallikrein activities. Inactivates membrane-anchored serine proteases activities such as MPRSS7 and TMPRSS11E. Inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. May also play a non-inhibitory role in seminal plasma and urine as a hydrophobic hormone carrier by its binding to retinoic acid (By similarity).
Subcellular location: Secreted, extracellular space {ECO:0000250}. Note=Localized on the plasma membrane overlying the acrosomal head of spermatozoa of ependymal spermatozoa and ejaculated sperm. Localized at the equatorial segment of acrosome-reacted spermatozoa. Localized in alpha granules in resting platelets and on the external plasma membrane and within the surface-connected cannalicular system in activated platelets (By similarity). {ECO:0000250}.
Interaction partners:
- Prothrombin
- Vitamin K-dependent protein C
- Plasminogen activator inhibitor 1
- Urokinase-type plasminogen activator
- Tissue-type plasminogen activator
- Vitronectin
- Serpin B6
- Antithrombin-III
- Serine
- Serine
Sequence:
MRFFPILCLVLFISHGVASRRHSHSKKKKAKESSVGAVGPPSSKDFAFRLYRALVSESPGQNVFFSPLSVSMSLGMLSLGAGLKTKTQILDGLGLSLQQGQEDKLHKGFQQLLQRFRQPSDGLQLSLGSALFKDPAVHIRDDFLSAMKTLYMSDTFSTNFGNPEIAKKQINNYVAKQTKGKIVDFIKDLDSTHVMIVVNYIFFKAKWQTAFSETNTHKMDFHVTPKRTTQVPMMNREDGYSYYLDQNISCTVVGIPYQGNAIALFILPSEGKMKQVEDGLDERTLRNWLKMFTKRRLDLYLPKFSIEATYKLENVLPKLGIQDVFTTHADLSGITDHTNIKLSEMVHKSMMEVEESGTTAAAITGAIFTFRSARPSSLKIEFTRPFLLTLMEDSHILFVGKVTRP
Protein: Stevor (Q8I201)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MLLFAFLFNAFLLSQRVKCINKIGNISLIKNNTQSISTKSRYLAEIERPNNPHYYNDPELKEIIDKLNKEAIKKYQKNHDPYEQLKEVVEKNQTKVTGGNDAEPMSTLEKDLLEIYEKLFGDKSHIMIKSNIYINQDDKSNDKNDKSCECANYKKYNQLLSSYSVDDAYLHNLKSGCVACVGTSALSSIITGLYGISAASTAAIEAIKTTSSATIITKLTKSLFGINFFSQTSIESAYITAGITSVEGELYAGLVTSTFLPYGIVAIVLILVIVALIMLYIWFYRRRKSSWKYAYKNHLST
Protein: SH3 domain-containing protein C23A1.17 (O42854)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Note=Localizes at the cell tip and barrier septum.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase pin1
- Protein scd2/ral3
- GTP-binding nuclear protein spi1
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL11m
- Large ribosomal subunit protein uL15m
- Mitochondrial GTPase 1
- Putative acyl carrier protein, mitochondrial
- Large ribosomal subunit protein uL29m
Sequence:
MSSFPTRVVALYPYRSSFSDDLEFDPGQVIDVVSNLDGDWYTGTYVDSDGNRKIGSFPKDFTEPAEDAVFVERASEMALHQPTPTSAVHSRNSSLGYAPSITRSIKSISNNTEHLGADTESYLSANDFIDSTSEALTKIVDVDTLSAPFGNDSNSRPHSLKNVEKLHTFSAPYTISEETPSCSTENDSLPLTATHTITGGEDAATGAAVTNTTTTHITTSTNTSTVIPSNPNSVFLVDCTHSQCPTDLPNIATTQHSLRYLDNASASAITVLERTHPAASSTMATESSHQSPSADSQAEELSKSQRVAKDDDPFVVSNTANSDEPASSSKPAKPLTDLNRAFSQRLNLDPQKPGKSQGEISEQEEDEYDDAESDEMHSPYSTHEPESEPEDQDEPSEKDDENKDVEEEQEQEQEEEQIDPEEAKRIALRERMAKMSGGIGMHVFGLPGLAAPIGRKNTLRRTPAKSSEEAKSTTNDSSPPKDSSSTSTQPTEQSNAQQAPSPKEEERPLPSEPSQNQPAEYRDTPDTPRNIMPLPGLMSADQPIKVTEPSNDADKAIVAEGPNNEEETKGPVIPETQETSEQQVHKTPSPEKQKVLSPPPIITNFDKETLASNEAHEAVPQKPSAPQVTRLMAPQDSSSVVTPSPTSLLDPARAVRKVIDGIDPPKEAGAGATADVESAANSPITPPRTWHSPDFTSKSFEPIERKLPSRISEVTEDSIDEDKQNEVDPSTSARALPPPGLRFGKVDTLASLAHDDLDDLPAVPRIFSPPPLPKTPSGEFGDNEFMFPKKSNRVRGHQSRPSTGSQLRNVVPVSIVTSGGRPALPDEMASPSSSIGHPLPSPPPADFNSLNVDFYEPHSYLESPAPEPQPSYEEESFNATVIHAPTPSTATFQGHPTISNVATPPLKQDVTESKASPVADASATHQSSTGLTQEITQLGSNMRLPTKLTRPSNDGRKASGPRPAAPPSIPPPLPVSNILSSPTSEPPKDHPPSAPLSKPVSTSPAAPLARVPPVPKLSSKAPPVPLPSADAPPIPVPSTAPPVPIPTSTPPVPKSSSGAPSAPPPVPAPSSEIPSIPAPSGAPPVPAPSGIPPVPKPSVAAPPVPKPSVAVPPVPAPSGAPPVPKPSVAAPPVPVPSGAPPVPKPSVAAPPVPAPSGAPPVPKPSVAAPPVPAPSSGIPPVPKPAAGVPPVPPPSEAPPVPKPSVGVPPVPPPSTAPPVPTPSAGLPPVPVPTAKAPPVPAPSSEAPSVSTPRSSVPSPHSNASPSPTSSSMASAAPARTSVSRSKSKAERHETSTSSRKSSKSGEHHHHHNEGHADSSSTRTSLAHQDSRKSLHRHLSRSSSRASKKPSIVSTTGPFNESFSAKPVEPCASEKWWLNSTAVPKSVVQMNDSVLYMIKEGITGQDKKYKSVHILFPDYSQTVLTATFNPHNQNITQLSQLQLAPPAQPSKARLDEEYACYGSTILKKARAYQGSMVGDGSAFTFVNSVMSILAHNLEPINKQTFGGVIYKNVGNVTVQQIGEIRPGDIVTFDKAKFSGQKGTLRSKYSLEVGKPMHYGIISEWDVSKLKIRVLEQGRESKKVSVASYKFGDLKSGEVTVWRVMRRSWLGWN
Protein: Inner kinetochore subunit CHL4 (CENP-N homolog) (Chromosome loss protein 4) (Chromosome transmission fidelity protein 17) (Constitutive centromere-associated network protein CHL4) (Minichromosome maintenance protein 17) (P38907)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Subcellular location: Nucleus {ECO:0000269|PubMed:12589047}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:12589047}. Note=Associated with kinetochores.
Interaction partners:
- Inner kinetochore subunit NKP1
- Inner kinetochore subunit MCM21
- Inner kinetochore subunit IML3
- Inner kinetochore subunit OKP1
- Inner kinetochore subunit AME1
- Inner kinetochore subunit CTF19
- Inner kinetochore subunit CTF3
- Inner kinetochore subunit MCM22
- Inner kinetochore subunit MCM16
- Inner kinetochore subunit NKP2
Sequence:
MSNELRLEDNYVPTSDTLVVFKQLMKLPVTVLYDLTLSWFAKFGGSFDGDIYLLTETLDLLIEKGVRRNVIVNRILYVYWPDGLNVFQLAEIDCHLMISKPEKFKWLPSKALRGDGKPYVVKLQPAKFIENLQTDLAKIYHCHVYMFKHPSLPVLITRIQLFDSNNLFLSTPNIGSINKESLYNKLDKFQGKPLISRRPYYVAFPLNSPIIFHSVDKDIYARLVLQSISRTISERETIIFKPVQKIPVKSIHNIMTLLGPSRFAESMGPWECYASANFERSPLHDYKKHQGLTGKKVMVREFDDSFLNDDENFYGKEEPEIRRLRLEKNMIKFKGSANGVMDQKYNDLKEFNEHVHNIRNGKKNEDSGEPVYISRYSSLVPIEKVGFTLKNEINSRIITIKLKFNGNDIFGGLHELCDKNLINIDKVPGWLAGENGSFSGTIMNGDFQREQVAKGGLL
Protein: UDP-arabinopyranose mutase 1 (EC 5.4.99.30) (Reversibly glycosylated polypeptide 1) (AtRGP1) (UDP-L-arabinose mutase 1) (Q9SRT9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf) in vitro. Preferentially catalyzes the formation of UDP-Arap from UDP-Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5. Is not active on other UDP-sugars (UDP-Gal, UDP-Xyl, UDP-Glc, GDP-Man and GDP-Fuc). Functions redundantly with RGP2 and is essential for proper cell walls and pollen development. Probably involved in the formation of the pectocellulosic cell wall layer intine. Is probably active as heteromer in vivo.
Subcellular location: Cytoplasm, cytosol. Golgi apparatus. Note=Soluble and associated with peripheral membrane and endomembrane system. {ECO:0000269|PubMed:17071651, ECO:0000269|PubMed:21478444}.
Interaction partners:
- UDP-sugar pyrophosphorylase
- UDP-arabinopyranose mutase 2
- UDP-arabinose 4-epimerase 1
- Cyclase-associated protein 1
- At4g14145
- Actin-related protein 4
- Actin-related protein 2
- Actin-related protein 2/3 complex subunit 3
- At4g30390
- Small ribosomal subunit protein RACK1y
Sequence:
MVEPANTVGIPVNHIPLLKDELDIVIPTIRNLDFLEMWRPFLQPYHLIIVQDGDPSKTIAVPEGFDYELYNRNDINRILGPKASCISFKDSACRCFGYMVSKKKYIFTIDDDCFVAKDPSGKAVNALEQHIKNLLCPSTPFFFNTLYDPYREGADFVRGYPFSLREGVSTAVSHGLWLNIPDYDAPTQLVKPKERNTRYVDAVMTIPKGTLFPMCGMNLAFDRELIGPAMYFGLMGDGQPIGRYDDMWAGWCIKVICDHLGLGVKTGLPYIYHSKASNPFVNLKKEYKGIFWQEDIIPFFQSAKLTKEAVTVQQCYMELSKLVKEKLSPIDPYFDKLADAMVTWIEAWDELNPPTKA
Protein: D-amino acid oxidase regulator (Protein G72) (P59103)
Organism: Homo sapiens (Human)
Function: Seems to activate D-amino acid oxidase.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:18544534}. Golgi apparatus {ECO:0000269|PubMed:12364586, ECO:0000269|PubMed:18544534}. Mitochondrion {ECO:0000269|PubMed:17684499, ECO:0000269|PubMed:25078755}. Note=May transiently pass through the Golgi apparatus. {ECO:0000269|PubMed:18544534}.
Interaction partners:
- D-amino-acid oxidase
- Dysbindin
- Disrupted in schizophrenia 1 protein
- Zinc finger protein 804A
- Catechol O-methyltransferase
- Regulator of G-protein signaling 4
Sequence:
MLEKLMGADSLQLFRSRYTLGKIYFIGFQRSILLSKSENSLNSIAKETEEGRETVTRKEGWKRRHEDGYLEMAQRHLQRSLCPWVSYLPQPYAELEEVSSHVGKVFMARNYEFLAYEASKDRRQPLERMWTCNYNQQKDQSCNHKEITSTKAE
Protein: Uncharacterized protein (Q57W20)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MERTNRARVTFGDVTVVPYAGTRPGPAGNKRASQADESSSYSYSDYSDDYSYYGSYTQSSRTNSNESSSYSQTIESSGTKTQPPPAREQQQQQQQQQQQQSYTQSGQLQPQLQVQPLAPQHPPRAPVAPQQPVPSKSVQGPRGNSAARVSTESYTGSYSSYSYSYSDSTDEGHNVVASARSGHVAGAAQLDSEKKRAAAGTTTNISAPKAPIGSMQMPTITQQTSQTSGHQHPPMAQPHLQMGVQQVSPWAQQVPVGNQQPPAVHSQPPANIQQRHGDDPLMSARSRQQPPTGSRRPSLRTPEIPKEDQQQTHTSVQQRPANAKYQQAVVGHQHPPMAQPHLQMGVQQVSPWAQQVPVGNQQPPAVHSQPPANIQHPRVGSQQPVGMAHKYQAARTQQMPSKTQLGRAPATSTEGLKIDNFSGSGSDYYSYSPYGSHSGSYTGSYSSYSYTQRMPGQSYSSGGDYTTTVKAAAPARPVEPPKPETHSHTAPPAASPIVRGRVQDDDSYSYSYSYSYGSVSSPEVKHPLPPSHVVKAPQPEQDANVVSVSSSELGYTGSYYDSEYDYSYDYSESATKTQKAVEEPKGAEQHSKSTVETTTSLIKPTTSGYTGSESYSASKSGDYSIELSGEGGVTSSESTEIPSPARIRKTILLAAPSEAEPRFHSLPRGCIVPHSSMEDTLSSFLDQLAELQVETMERNRVLKVLNTEVEAAKDLKERKVSDSQRIASDEANSPADIVEAPISVIPSRNLTRKSLMFALRAVGVEKAKERYKILEDVDTVVPREKARTILEYYGSRCLTEKVMSMFVAYDEFYSGEVPLSIAFEILEYCGLVTQTVGKFKIFLRPQVSQGQILLCVADQPQEATENIVDDAEGEKRWIQPQTYETTVRCCGEGWKYGDHKVYWNGESGDVFVGSFIVAKGITERKVAVQLLRYIEAFLYVCHAIMVVTVGTGMKLRVLYTPLVEKLLNPTVKGVTDATSFLYELAFGSVFNPKKYVKLLANNSNLRDRYLCEGDDAVLHDTIRPKHLVPKAPFMINGDKDDELNTLLMSTANSYTTVSANIWTQKGVEGCYLEVGVEKLRISEKVPENARCYCLVSVRKSKDSEWMTAEVLQAVSVGKANKGGFKWKFGKSSSDRLFFTGAIEDSLYVEACYDIVDASGETTTYCVGHVLVPCGKLKSGKLPVRPGSCYTYTPLDEALKQPVEASGGFCAPRRKTAGPPAKSLTVTIKRLRSKDVPDLKTLPSRCLSLHRHVSLMSLMCAAVISGRDGGSHPLRWLRQQQVQCCFMVTADSELMDILQGLWKRVMKGKLGPKPQNLGQKYKRILILATKVVAAHNNITGGDQGIITDVVAGKKGIPFTENMNRPLRPVCV
Protein: Probable malate:quinone oxidoreductase 2 (EC 1.1.5.4) (MQO 2) (Malate dehydrogenase [quinone] 2) (Q9HVF1)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Citrate synthase
- Fumarate hydratase class II 2
- Fumarate hydratase class II 1
- Malate synthase G
- NADP-dependent malic enzyme
- Fumarate hydratase class I
- Phosphoenolpyruvate carboxylase
- NAD-dependent malic enzyme
- Phosphoenolpyruvate carboxykinase
- Oxaloacetate decarboxylase
Sequence:
MAQNDHETVDMLLVGAGIMSATLAVLLKELDPNLKMEVVELQESGAIESSNPWNNAGTGHAGLCELNYTPQSADGSIDIKKAVGINTMFEVSKQFWSHLVAKGTFGSPKTFINPVPHLSFVRGSEGIAYLKKRFESLTKHHAFETMVYSEDKATLAEWMPLMMPGRPADEAIAATRVEGGTDVNFGALTNQLLQHLAQQPGAQIRYNQKVTHLRRADNGWRVTVKDTRNGGDREIQARFVFLGAGGGALPLLQLSGIPEGKGFGGFPVSGQWLRCDNPEIVKQHQAKVYSQAEVGSPPMSVPHLDTRVVDGKKSLLFGPYAGFSTKFLRHGSFLDLPLSVRPGNILPMLSVARDNMDLTRYLIGQVMQSPEQRLEALRKFYPEARAEDWRLEVAGQRVQIIKKDPKKGGILQFGTELVAAHDGSIAALLGASPGASVTVSIMLGLIERCFPEQARSPEWSAKLKEIFPAREKELESDAELYRSVSSRCSEVLELTAKNDVQAPVNAE
Protein: Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6) (P60660)
Organism: Homo sapiens (Human)
Function: Regulatory light chain of myosin. Does not bind calcium.
Interaction partners:
- Myosin regulatory light chain 12B
- Myosin-9
- Myosin-10
- Myosin regulatory light chain 12A
- Myosin regulatory light polypeptide 9
- Myosin-11
- Myosin light chain 6B
- Actin, cytoplasmic 1
- Myosin-14
- Actin, cytoplasmic 2
Sequence:
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG
Protein: Acyl-coenzyme A oxidase 2, peroxisomal (AOX 2) (EC 1.3.3.6) (Long-chain acyl-CoA oxidase) (AtCX2) (O65201)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the desaturation of long-chain acyl-CoAs to 2-trans-enoyl-CoAs. Active on substrates longer than C14 and mostly with C18-CoA. Activity on long-chain mono-unsaturated substrates is double than with the corresponding saturated substrates.
Subcellular location: Peroxisome {ECO:0000255}.
Interaction partners:
- Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2
- 3-ketoacyl-CoA thiolase 2, peroxisomal
- 3-ketoacyl-CoA thiolase 1, peroxisomal
- 3-ketoacyl-CoA thiolase 5, peroxisomal
- Peroxisomal fatty acid beta-oxidation multifunctional protein AIM1
- Probable enoyl-CoA hydratase 1, peroxisomal
- Probable acyl-CoA dehydrogenase IBR3
- Acetyl-CoA acetyltransferase 1
- Acetyl-CoA acetyltransferase 2
- Peroxisomal acyl-coenzyme A oxidase 1
Sequence:
MESRREKNPMTEEESDGLIAARRIQRLSLHLSPSLTPSPSLPLVQTETCSARSKKLDVNGEALSLYMRGKHIDIQEKIFDFFNSRPDLQTPIEISKDDHRELCMNQLIGLVREAGVRPFRYVADDPEKYFAIMEAVGSVDMSLGIKMGVQYSLWGGSVINLGTKKHRDKYFDGIDNLDYTGCFAMTELHHGSNVQGLQTTATFDPLKDEFVIDTPNDGAIKWWIGNAAVHGKFATVFARLILPTHDSKGVSDMGVHAFIVPIRDMKTHQTLPGVEIQDCGHKVGLNGVDNGALRFRSVRIPRDNLLNRFGDVSRDGTYTSSLPTINKRFGATLGELVGGRVGLAYASVGVLKISATIAIRYSLLRQQFGPPKQPEVSILDYQSQQHKLMPMLASTYAYHFATVYLVEKYSEMKKTHDEQLVADVHALSAGLKSYVTSYTAKALSVCREACGGHGYAAVNRFGSLRNDHDIFQTFEGDNTVLLQQVAADLLKRYKEKFQGGTLTVTWSYLRESMNTYLSQPNPVTARWEGEDHLRDPKFQLDAFRYRTSRLLQNVAARLQKHSKTLGGFGAWNRCLNHLLTLAESHIETVILAKFIEAVKNCPDPSAKAALKLACDLYALDRIWKDIGTYRNVDYVAPNKAKAIHKLTEYLSFQVRNVAKELVDAFELPDHVTRAPIAMQSDAYSQYTQVVGF
Protein: Sec14p-like phosphatidylinositol transfer family protein (F4HZ25)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395}.
Interaction partners:
Sequence:
MSGSLDRFARPCFEGVSSNDERRERRSDFEVSEDEKKTRIGNFNFKKKAAKASSKLRHSLKKKGSSRRRSSDRTFSLTIEDIHDVEELRAVDEFRNLLVSENLLPPTLDDYHIMLRFLKARKFDIGKTKLMWSNMIKWRKDFGTDTIFEDFEFEEFDEVLKYYPHGYHGVDKEGRPVYIERLGLVDPAKLMQVTTVERFIRYHVREFEKTVNIKLPACCIAAKRHIDSSTTILDVQGVGFKNFSKPARDLIIQLQKIDNDNYPETLHRMFIINGGSGFKLVWATVKQFLDPKTVTKIHVIGNKYQNKLLEIIDASQLPDFLGGTCTCADRGGCMRSDKGPWNDPEILKMLQSGGPLCRHNSALNSFSRVSSCDKPSFSGIKASDTSTAESGSEVEEMASPKVNRELRVPKLTPVCEDIRGTAISYPTDSSEYDSPMVDKVVDVAWMAHEKPKASKGSEDTPDSGKIRTVTYIWRWLMMFFVNLFTLLISLALPQREGHSQSESSVDGPNARESRPPSPAFATIAERNVFSSVVNRLGDLEKQVETLHSKRHEMPREKEELLNTAVYRVDALEAELIATKKALHEALMRQDDLLAYIDREEDEKYHKRIHLRGFCWENRKRRFVNTNPIERTMFISKIRSHKQRFDTFGGNFRRMFFQLIFKVHFYLYQ
Protein: Protein Nef (3'ORF) (Negative factor) (F-protein) [Cleaved into: C-terminal core protein] (P03404)
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
Function: Factor of infectivity and pathogenicity, required for optimal virus replication. Alters numerous pathways of T-lymphocyte function and down-regulates immunity surface molecules in order to evade host defense and increase viral infectivity. Alters the functionality of other immunity cells, like dendritic cells, monocytes/macrophages and NK cells.
Subcellular location: Host cell membrane {ECO:0000255|HAMAP-Rule:MF_04078}; Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_04078}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_04078}. Virion {ECO:0000255|HAMAP-Rule:MF_04078}. Secreted {ECO:0000255|HAMAP-Rule:MF_04078}. Host Golgi apparatus membrane {ECO:0000255|HAMAP-Rule:MF_04078}. Note=TGN localization requires PACS1. Associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved. {ECO:0000255|HAMAP-Rule:MF_04078}.
Interaction partners:
Sequence:
MGGKWSKSSVIGWPAVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAANNAACAWLEAQEEEKVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
Protein: Transcription factor MYB58 (Myb-related protein 58) (AtMYB58) (Q9SA47)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds DNA to the AC cis-elements 5'-ACCTACC-3', 5'-ACCAACC-3' and 5'-ACCTAAC-3' of promoters and specifically activates lignin biosynthetic genes during secondary wall formation mediated by SND1.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:19122102}.
Interaction partners:
- NAC domain-containing protein 12
- NAC domain-containing protein 43
- NAC domain-containing protein 66
- NAC domain-containing protein 73
- NAC domain-containing protein 10
- NAC domain-containing protein 30
- Homeobox protein knotted-1-like 7
- Cytochrome P450 84A1
- NAC domain-containing protein 37
- Trans-cinnamate 4-monooxygenase
Sequence:
MGKGRAPCCDKTKVKRGPWSHDEDLKLISFIHKNGHENWRSLPKQAGLLRCGKSCRLRWINYLRPDVKRGNFSAEEEDTIIKLHQSFGNKWSKIASKLPGRTDNEIKNVWHTHLKKRLSSETNLNADEAGSKGSLNEEENSQESSPNASMSFAGSNISSKDDDAQISQMFEHILTYSEFTGMLQEVDKPELLEMPFDLDPDIWSFIDGSDSFQQPENRALQESEEDEVDKWFKHLESELGLEENDNQQQQQQHKQGTEDEHSSSLLESYELLIH
Protein: Large ribosomal subunit protein uL29 (60S ribosomal protein L35) (Q8JHJ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity). Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P42766}.
Interaction partners:
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein bL21m
- FAU ubiquitin-like and ribosomal protein S30 fusion b
- Large ribosomal subunit protein uL6
- Small ribosomal subunit protein uS12
- Large ribosomal subunit protein uL16
- Large ribosomal subunit protein eL13
- Ribosomal protein S10
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein eS17
Sequence:
MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAIRRQLTKHEENLMTKKMQRKSRLYSIRKFAVKA