wanglab/gogpt-training-data huggingface dataset:
Protein: Tubulin alpha chain (A9PL21)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MRECISVHIGQAGIQVGNACWELYCLEHGIQPDGQMPGDKTVGGGDDAFNTFFSETGAGKHVPRAVFLDLEPTVIDEVRTGAYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFHAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVAVLLDNEAIYDICRRSLDIERPAYTNLNRLVSQVISSLTASLRFDGALNVDVNEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVAEITSSAFEPASMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNSTSVAEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGLESGEGDEDEGDEY
Protein: NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A) (H2KZ73)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MKVFAVLALVVASVLADTLPSVTLCPPETQTIFVLQHNTTVGARIRTIPTSNLAECSDHCSASLDCQGVEFKDGSCAVFRAGSEKATAGSQLLTKTCVKSDRVCQSPFQFDLFEQRILVGFAREVVPAANIQICMAACLNAFDTFGFECESAMFYPVDQECILNTEDRLDRPSLFVEESDDTVIYMDNNCAGSQCYPPYITQYIAVEGKQLKNELDRIINVDLDSCQALCTQRLSISSNDFNCKSFMYNNKTRTCILADERSKPLGRADLIATEGFTYFEKKCFASPNTCRNVPSFKRVPQMILVGFAAFVMENVPSVTMCLDQCTNPPPETGDGFVCKSVMYYYNEQECILNSETRESKPELFIPEGEEFLVDYFDITCHLKQEKCPTGQHLKAIRTINAALPEGESELHVLKASAAKGIKECVAKCFGLAPEKCRSFNYDKKTKSCDLLYLDGHNTLQPQVRQGVDLYDLHCLAVENDCSANKDDALFSRYLHTKQRGIPAKVYKVVSLNSCLEVCAGNPTCAGANYNRRLGDCTLFDAIDDDAEINEHTDFYKNLCVTKEIDTGASAAANVPETKHRVSGTVVEGKDSKSQLLATKKVKKPTIKNTEHRRAPESTVPIGPPVEVKAEAIQTICNYEGIKVQINNGEPFSGVIFVKNKFDTCRVEVANSNAATLVLGLPKDFGMRPISLDNIDDNETGKNKTKKGEETPLKDEIEEFRQKRQAAEFRDCGLVDLLNGTYKSTVVIQTNNLGIPGLVTSMDQLYEVSCDYSSMLGGRVQAGYNMTVTGPEANLIQPRGKIELGNPVLMQLLNGDGTEQPLVQAKLGDILELRWEIMAMDDELDFFVKNCHAEPGVAGGKAGAGEKLRLIDGGCPTPAVAQKLIPGAIEIKSSAVKTTKMQAFRFDSSASIRVTCEVEICKGDCEPVECALTGGVKKSFGRKKREVSNNIEEFETNRYLIPRRSHATTSIVIIDPLQQVNEPVAMSRASTLDLLREDAHEVQMIEEGSICLNSVTVFAIFGTLAVLILGQTVVIAHYAVRRFSSEKTA
Protein: Lipid A galacturonosyltransferase RgtD (Lipid A GalA transferase RgtD) (EC 2.4.1.-) (Galacturonic acid transferase RgtD) (GalAT RgtD) (Q1MLH5)
Organism: Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae)
Function: Involved in the modification of the lipopolysaccharide (LPS) lipid A moiety. Catalyzes the transfer of a galacturonic acid (GalA) residue to the 4'-position of 4'-dephosphorylated lipid A, using dodecaprenyl phosphate-GalA as the donor substrate. Acts before the other GalA transferases RgtA, RgtB and RgtC.
Subcellular location: Cell membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSPRSGLLIVLGFTLWRVVMLNFDATDFFVDEAQYWFWSQNLDLGYYSKPPMIAWVIRAMTELSGSNAIYWIRLLGPLIHMAAALVLMKTAKRFVGPEIEGWTGATYITLPGVALSSVFFSTDVILLFFIAIALLAYFGLTQRRSVGLALVMGLGVGLAFLTKYAVLFVVPGGAIALLLIPAARIAVRDVIIAVAVAAVVALPNLWWNLQHDNTTVRHTQDIAHWSELGINLRRGLEFFAAQFGVVGPIIFFAMLWAVYRMIRGRSDDREKMLVWLSMPVVLLITLQATVAKAYANWAVTAYVAGTILAVWLLYLKWPKGLRLSLTINGIASLLFPLATIFPHQLLLPNGDALMKRYLGRAEVSREAAALATQAGTDIIVTDNRDMVADLFYTLRDASYRIYARAPAGLPESYYEQEFALPADITGKVLFLTDGAFTCATETPEVLKNWQPTEGNYKGKTLSIYKVSATCLAP
Protein: Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) (P22934)
Organism: Rattus norvegicus (Rat)
Function: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity).
Subcellular location: Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- Tumor necrosis factor
- TNF receptor-associated factor
- Lymphotoxin-alpha
- Receptor-interacting serine/threonine-protein kinase 1
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Tumor necrosis factor ligand superfamily member 6
- FAS-associated death domain protein
- NF-kappa-B essential modulator
- RING-type E3 ubiquitin transferase
Sequence:
MGLPIVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDNLCPQGKYAHPKNNSICCTKCHKGTYLVSDCPSPGQETVCEVCDKGTFTASQNHVRQCLSCKTCRKEMFQVEISPCKADMDTVCGCKKNQFQRYLSETHFQCVDCSPCFNGTVTIPCKEKQNTVCNCHAGFFLSGNECTPCSHCKKNQECMKLCLPPVANVTNPQDSGTAVLLPLVIFLGLCLLFFICISLLCRYPQWRPRVYSIICRDSAPVKEVEGEGIVTKPLTPASIPAFSPNPGFNPTLGFSTTPRFSHPVSSTPISPVFGPSNWHNFVPPVREVVPTQGADPLLYGSLNPVPIPAPVRKWEDVVAAQPQRLDTADPAMLYAVVDGVPPTRWKEFMRLLGLSEHEIERLELQNGRCLREAHYSMLEAWRRRTPRHEATLDVVGRVLCDMNLRGCLENIRETLESPAHSSTTHLPR
Protein: Shal K[+] channel interacting protein, isoform H (A0A0B4KH49)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAVSNIVCEWLRALGLAQYAESFLDNGYDDLEICKQVGDPDLDAIGVENPAHRHKLLKSIRSLREKGAASVYFMLNDPNSLSGSMEILCETPPNNELELVLREQLETDGVRLTAHPYSTPVSLAFNLY
Protein: Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127 homolog) (Hepatocellular carcinoma-associated antigen 127-like) (Q7T3I0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in GABAergic and V2 interneurons differentiation. Involved in motoneuron development and in neuromuscular junction formation.
Subcellular location: Nucleus {ECO:0000269|PubMed:26056227}. Cytoplasm {ECO:0000250|UniProtKB:Q9NQZ6}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9NQZ6}.
Interaction partners:
Sequence:
MADEQEIMCKLENIKEIRNKTIQMEKIKSRLRTEFEALESEEKHLREYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSESDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLSQEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQAARKQDARQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKPDE
Protein: Putative calpain-like cysteine protease A (EC 3.4.22.-) [Cleaved into: Putative processed calpain-like cysteine protease A] (Q8MUF9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Has a weak caseinolytic activity.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:12578394}.
Interaction partners:
- Penta-EF hand domain-containing protein 1
- Penta-EF hand domain-containing protein 2
- Charged multivesicular body protein 4
- Vacuolar protein sorting-associated protein 4
- Probable serine/threonine-protein kinase roco11
- Probable serine/threonine-protein kinase roco6
- Probable serine/threonine-protein kinase roco5
- Probable serine/threonine-protein kinase qkgA
- Probable serine/threonine-protein kinase roco8
- Hisactophilin-3
Sequence:
MLTTESPTTTTTTTTTTTSSPSSDIRDKFIFGNLEVKVKEVKGCQLHFLNVKCELALKKTEIKTKPLANHTFFDVFSFRVSAATSELEIEAWKKNFLFKDKMTGSLTIPINDLLHANGEAKWYPLSNKKPRSSRVKKENITNSNNKDNNTASPSSPDEAQEKGDEDQHHSADESPAEETSPTTGRPRSVSMPAKKVKAAPEICLEIKFVLNEPPKEVLKGIVLDGVWNSENNFGSLINNPHWIKCTQYLLSIKDEITPITLKLRQPEGTDQRCSFFVINYDPFYNGSKKVILDTTNDIKKVSSFNSPIPATSVDCKIDLEPGQYCIIPYAESFAFSGTYKFNLDSEKLDNCEFYALPKSQEQAWNEITVDGLWTTATNGGGDINILGWTKNPQYSFTLTKKSRACVLLSQDDNDKSVGFYVIKQLDAGKRAIEFREQVGKTESFKFSCSTGCTLTLDEGTYIVIPSTYDHGIEGAFHLTLFTDDKNATFQPLTNAFQEVEQVKGTWVGKSAGGSPNQPTFFNNPQFHLKVPASDKDEVIAVQLIQDSTIADEGIGFIVLSRDSHSEPLTAQDFQNEMVFTKTSNWEKRNDIVCRLHVKPESPREFTIIPSTFDPSVNRSFKLQVYSDVSISLDEIEQKDESSDSEQNDD
Protein: Lysine--tRNA ligase, cytoplasmic (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) (Lysyl-tRNA synthetase 1) (AtKRS-1) (Q9ZPI1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (By similarity). Promotes aminoacylation of non-cognate tRNAs and translational recoding of lysine at nonsense codons.
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:16251277, ECO:0000305|PubMed:16297076}.
Interaction partners:
- Methionine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Isoleucine--tRNA ligase, cytoplasmic
- Glutamate--tRNA ligase, cytoplasmic
- Glutamine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, chloroplastic/mitochondrial
- Proline--tRNA ligase, cytoplasmic
- Arginine--tRNA ligase, chloroplastic/mitochondrial
- Isoleucine--tRNA ligase, chloroplastic/mitochondrial
- Arginine--tRNA ligase, cytoplasmic
Sequence:
MEGAADQTTKALSELAMDSSTTLNAAESSAGDGAGPRSKNALKKEQKMKQKEEEKRRKDEEKAEKAKQAPKASSQKAVAADDEEMDATQYYENRLKYLAAEKAKGENPYPHKFAVSMSIPKYIETYGSLNNGDHVENAEESLAGRIMSKRSSSSKLFFYDLHGDDFKVQVMADASKSGLDEAEFLKLHSNAKRGDIVGVIGFPGKTKRGELSIFPRSFILLSHCLHMMPRKADNVNAKKPEIWVPGQTRNPEAYVLKDQESRYRQRHLDMILNVEVRQIFRTRAKIISYVRRFLDNKNFLEVETPMMNMIAGGAAARPFVTHHNDLDMRLYMRIAPELYLKQLIVGGLERVYEIGKQFRNEGIDLTHNPEFTTCEFYMAFADYNDLMEMTEVMLSGMVKELTGGYKIKYNANGYDKDPIEIDFTPPFRRIEMIGELEKVAKLNIPKDLASEEANKYLIDACARFDVKCPPPQTTARLLDKLVGEFLEPTCVNPTFIINQPEIMSPLAKWHRSKSGLTERFELFINKHELCNAYTELNDPVVQRQRFADQLKDRQSGDDEAMALDETFCNALEYGLAPTGGWGLGIDRLSMLLTDSLNIKEVLFFPAMRPPQEESAAAQAPLTEEKK
Protein: Lysine-specific histone demethylase 1B homolog (EC 1.14.99.66) (Amine oxidase family member 1) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2) (Q21988)
Organism: Caenorhabditis elegans
Function: Histone demethylase that demethylates di-methylated 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed (By similarity). Plays a role in the mitotic development of the germline. May be involved in H3 demethylation in mitotic cells including gut and embryonic cells. Plays a role in sensitivity upon interstrand cross-link DNA damage, probably by positively regulating the expression of mlh-1. Plays a role in developmental growth and lifespan regulation in response to ultraviolet-induced damage. No obvious role in larval development, sex chromosome segregation or for regulating meiotic crossover frequency.
Subcellular location: Nucleus {ECO:0000269|PubMed:34329293}. Note=Only localizes to 5% of premeiotic tip and pachytene nuclei. {ECO:0000269|PubMed:34329293}.
Interaction partners:
- Phytoene synthase
- REST corepressor spr-1
- TM2 domain-containing protein C41D11.9
Sequence:
MTTELEIDDRKEEEAQIPGETSESEEGDEPVKMNRVKRACAMAAESLKEAKRIKNMLMEEECVLQLGNCKKTASYGHRLSKTEACCPSCFSVAFRGKDYENEFTIWKQKAMDGQTHVRSEQFVKRYVNSCFLPYYAKCHQCSKYSKLITSDSLSAQQLSDFKCDCASTIESPKIERVREDSEWCFNEFGHPPLLQNNISYDLLVDHYVTRTTGMDATCQEKAALIDNGGIEFRDTRRIMNMFYVPFTDVIANIVHPEFMETDEKFAFPKFADDPISIYYLQVRNTIIAMWLKHPFVELTVKMIEPQIIVRGHARIFFIEHLIHPILEFLTIKGVVNYGAFDFRIDPLNGMRPKIAIIGAGISGISTARHLKHLGIDAVLFEAKDRFGGRMMDDQSLGVSVGKGAQIIVGNINNPITLLCEQIGIKYRNSNFFCPLIDENGRCFTLERKELDDQVDLHYNNVLDAIRNKYQSDRNFPDVPLEVTNFRHFTEMFSKMSSGLLSAADLDSLYTPEFEKLLDFHLGNLEFSCGTHVSNLSAKDYDHNEKFGNFAGEHAVITDGAQRIIDFLATGLDIRLNCPVKCIDWGRDDRKVKIFFENAEQAAEEFDKVVITTSLSVLKSNHSKMFVPPLPIEKQKAIDDLGAGLIEKIAVKFDRRFWDTVDADGLRTEYFGKVSDCKTDRSLFNIFYDFSGKDPNGEDTFVLMSYVTAEHVNLVNVLTESEVADKFCATLRKMFPSAVINPLGHMMSHWGADRFVGMSYTFVPFGSDGDATYNQLKKSIDEKLYFAGEHTIAAEPQTMAGAYISGLREAGQIVMSLKRDSATFE
Protein: Actin-related protein 5 (Q9VEC3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:16618800}.
Interaction partners:
- RuvB-like helicase 1
- RuvB-like helicase 2
- Actin-related protein 8
- LD10749p
- BcDNA.LD23876
- Chromatin-remodeling ATPase INO80
- Helicase domino
- Brahma associated protein 55kD
- Uncharacterized protein, isoform D
- Polycomb protein PHO
Sequence:
MAGKRVLVIDNGSYECRVGWSDSKEPDLRFRNVLTKPRKDRKKEAAASEGSASQTTVEQSAEIQVGNDITNIEAVRAHLKSPFERNVITNWNHQEQIFDYIFTKMGFDGQDKIDHPIILTEALANPNFCRQQMNELLFECYGIPSVSYGIDALYSWKHHQQKQKNISDALIISFGYSTTHVIPVLDGKLQLEHVRRLNVGGYHIITYLFRLMQMKYPVHLNAITISRMEKLVHEHCHIAVDYKEELVQWAQMDYYDEHIMKIQLPYNAVTATNAMLTAEQKQEKRRELAHRLLDIKKNREQEKLREDEQQLFVYNKLRQLYEQKKLDKFERALQQQQIGTLEDLDSLIATINSRIKRAQERAQSGPRPSKQQERLNKMPKPPEGMSQADWLAELQGKREKILGRKQARQQQRSEQAKRHTHAAQERMRIISSLAKNEKRRKANGEEEDDGFGMNDNDWDVYKRINRYNDDSDSDADNEKLMQFDKILNHYDANTDGNSNVPPQSAAENYQLHFGVENIRVPEVLFQPSMIGCSEAGLAELIAFVLKLFPAAEQQRLVEHVYLTGGCAQFKGLKERLIKELMEMRPFQSKFAIYESDEPTLSAWLGACVHAGEPTFGQTLTTRQDHQEHGREFFREHTASNIFYPTPKD
Protein: Auxin-responsive protein IAA12 (Indoleacetic acid-induced protein 12) (Q75GK1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Auxin response factor 11
- Transport inhibitor response 1-like protein Os05g0150500
- Auxin response factor 14
- Auxin response factor 9
- Auxin response factor 7
- Auxin response factor 3
- Auxin response factor 2
- Auxin response factor 15
- Auxin response factor 1
- Auxin response factor 16
Sequence:
MEAAVGYAADSLIKATELRLGLPGTADDLPSTPRGKKRAAAAEDNNANAAAADDDEHDAVEAAPPVAKAQVVGWPPVRSYRKSCFQQQSAAASKSKAAVSSCNNKDEPITKNAAPAPAASSAAAANGGSLVKVSMDGAPYLRKIDLRMYKGYRELREALEAMFVCFSGAADGANPSEFAITYQDKDGDLMLVGDVPFDMFTSTCKKLRIMKRSEATGLGSPRQMKI
Protein: Cytochrome b5 A (Q75JN6)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSEKTFTRQEVAKHCSLNSLWIIYNDDVFDVTNFVVEHPGGEEVLKGNGGKDATQEFDDVGHSASAIAKMQSLRIGRIEGAKPREEKKKEIKKTTTTTSAPKQQESAGLGLLKIPLIIIVLAIAAYFFMGDQQ
Protein: BG642312, isoform A (BG642312, isoform B) (FI23143p1) (Q0E8H8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Accessory gland-specific peptide 26Aa
- Accessory gland protein Acp36DE
- Uncharacterized protein, isoform A
- Uncharacterized protein, isoform B
- Lectin-46Ca
Sequence:
MPINRINPSTAMRSASLKFYLICLLVICVIGWSAGAPSPQLSRKELEDRYRQKPPVPDERDADAELDSAYDRNTRRP
Protein: Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon) (Q86WA8)
Organism: Homo sapiens (Human)
Function: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
Subcellular location: Peroxisome matrix {ECO:0000255|HAMAP-Rule:MF_03121, ECO:0000269|PubMed:14561759, ECO:0000269|PubMed:18281296, ECO:0000269|PubMed:22002062}.
Interaction partners:
- Peroxisomal leader peptide-processing protease
- Peroxisomal targeting signal 1 receptor
- Protein cereblon
- Mitochondrial disaggregase
- ATP-dependent clpX-like chaperone, mitochondrial
- ATP-dependent Clp protease proteolytic subunit, mitochondrial
- 60 kDa heat shock protein, mitochondrial
- GrpE protein homolog 1, mitochondrial
- T-complex protein 1 subunit gamma
- Sterol carrier protein 2
Sequence:
MSSVSPIQIPSRLPLLLTHEGVLLPGSTMRTSVDSARNLQLVRSRLLKGTSLQSTILGVIPNTPDPASDAQDLPPLHRIGTAALAVQVVGSNWPKPHYTLLITGLCRFQIVQVLKEKPYPIAEVEQLDRLEEFPNTCKMREELGELSEQFYKYAVQLVEMLDMSVPAVAKLRRLLDSLPREALPDILTSIIRTSNKEKLQILDAVSLEERFKMTIPLLVRQIEGLKLLQKTRKPKQDDDKRVIAIRPIRRITHISGTLEDEDEDEDNDDIVMLEKKIRTSSMPEQAHKVCVKEIKRLKKMPQSMPEYALTRNYLELMVELPWNKSTTDRLDIRAARILLDNDHYAMEKLKKRVLEYLAVRQLKNNLKGPILCFVGPPGVGKTSVGRSVAKTLGREFHRIALGGVCDQSDIRGHRRTYVGSMPGRIINGLKTVGVNNPVFLLDEVDKLGKSLQGDPAAALLEVLDPEQNHNFTDHYLNVAFDLSQVLFIATANTTATIPAALLDRMEIIQVPGYTQEEKIEIAHRHLIPKQLEQHGLTPQQIQIPQVTTLDIITRYTREAGVRSLDRKLGAICRAVAVKVAEGQHKEAKLDRSDVTEREGCREHILEDEKPESISDTTDLALPPEMPILIDFHALKDILGPPMYEMEVSQRLSQPGVAIGLAWTPLGGEIMFVEASRMDGEGQLTLTGQLGDVMKESAHLAISWLRSNAKKYQLTNAFGSFDLLDNTDIHLHFPAGAVTKDGPSAGVTIVTCLASLFSGRLVRSDVAMTGEITLRGLVLPVGGIKDKVLAAHRAGLKQVIIPRRNEKDLEGIPGNVRQDLSFVTASCLDEVLNAAFDGGFTVKTRPGLLNSKL
Protein: Junctional cadherin 5-associated protein (Junctional protein associated with coronary artery disease) (JCAD) (Q9P266)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, adherens junction {ECO:0000250|UniProtKB:Q5DTX6}. Note=Colocalizes with CDH5/VE-Cadherin in endothelial cells but not in epithelial cells. {ECO:0000250|UniProtKB:Q5DTX6}.
Interaction partners:
- Serine/threonine-protein kinase LATS2
Sequence:
MYSVEDLLISHGYKLSRDPPASREDNPKGRQAARTGTRAGQGLQNGHEDGPAALAHRKTSAGKGHVSDSESRRSTPRGHGEPQSTSASRTSEAGFCNQPPSAWSSHPPTGNDQAYRRRGRQEARSQKPREHENLEARGMAQAHSLPVHVREGPWEVGGRSEHVMKKPVWEEELRMSGPAKWQNVSLESWNQPRKLGRQMSDGDGERLFQDLYPFIQGEHVLNSQNKGKSRSLPRVLSPESLSCTEIPIPLNERHSPKMPPYPPTCAPNLDSTRNSEKSGCSAPFPRPKFGRPLKPPSYSSHQQSRGGADSSDSQDSQQMDAYVPRHELCLSDPGLEPPVYVPPPSYRSPPQNIPNPYLEDTVPINVCGGHSQQQSPTEKAGASGQPPSGPPGTGNEYGVSPRLPQGLPAHPRPVTAYDGFVQYIPFDDPRLRHFKLAQPQGFCEDIKLDDKSYNSSPVTAQEPAHGGMQPDGAIWNPQSLIPPSGDERGLVLADSSPRWLWGQPPGDGENSGLPNQRDRCVARGQWPDVRGSQHGHTGRQVSSPYSQGESTCETQTKLKKFQTGTRTKKSSKKKMNETIFCLVSIPVKSESHLPDRDMDNNDLKPSADQKNGSDKSPALQEQSLLSMSSTDLELQALTGSMGGRTEFQKQDLGEPEEDRQTNDLSFIHLTKHRELKHSGSWPGHRYRDQQTQTSFSEEPQSSQLLPGAKLGGPSRAALSPKCSDPAASEAQTHTAFPTGDHKQRPSARNLKGHRSLSPSSNSAFSRTSLSVDQAPTPKAGRSQPCVDVHGLGAHPGPKREVVKGEPTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEESSSSSSSSSSSSEESEAEPQQENRAHCRQEDVGFRGNSPEMRVEPQPRMWVPESPVCRSGRGESKSESWSEELQPGHPRAWPPSPGRFRVEEGGGAPFCSADGSTSAEKRHLEVSNGMDELAGSPFPVTRMSSRSSDAKPLPASYPAEPREPQESPKITSAFSSVKPSEAVPRKFDSGGERGAGLPLSLSNKNRGLSAPDLRSVGLTPGQEQGASELEGSLGEASTIEIPPGESLQARAARILGIEVAVESLLPGIRRAGQNQPAEPDASACTPESPQEELLSRPAPADVPRVSTDAFYGRRKCGWTKSPLFVGDRDSARRAPQAFEHSDVDGVVTSTDPVPEPEPSPLESKFFEQKDVETKPPFRSTLFHFVERTPSVAGSEKRLRSPSKVIESLQEKLASPPRRADPDRLMRMKEVSSVSRMRVLSFRNADSQEDAEELKATTRGQAGLPGGLVSPGSGDRAQRLGHSLSVSKDSISREEKEHPAAQKEKSMDQDFWCPDSYDPSRVERV
Protein: FAS1 domain-containing protein YLR001C (Q07895)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Vacuole membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MNMAIQTIKYIFWLLPILGLTQALLQNPGDDFPFSTVIDILSENVEFSTFLRIIQKTGHVQYLNELQNFTLFAPINSAFIKGDQTTDQFEEHFHIEDFLIHDRVLQVRDLENGTYLEKRAAKAPLLLRKHERHCFVNEIAVVEPDLLPSFQNASLQGINNLLLIQPQINELLVQLDEETQDLKIFSDFISSFSNYNAYTNSSTVLVPLDVNFRKFFNTIEINYLLDKYNKLGKSNTISQAKWAADRTSLLQELIIDDVYGGILPKELILENKNNRKLFMKSNSEGTSVSVNNSDYSPISNRIFEIGVVHGFSDLDFLRTHIQFDAEKYLHGLNCSEFVKELYFRDLEKFIQNGRKITIFVPQASFNEDRGYTKPSLLYHFVEGKIDLEQDFSSLRPIQYAPTQIYDSAFCSSAKRLGGHCQKFKITRSNKGYYINGRFKILNTKPYEIGNTSIYSIDDDLQLPGDLVLSLAPENHCSISLMLLKELNLLDLPSNHKGYTILLPCMNSWDNNDLTIDYLRSNKTALNLLMRNLIFEDLIYSNNYSISTTVKNLYGNSVSIGVQKIVGSQNLTKISVSTIKESIIIEESSDIFFNQGVIHPIDQLDFPVDLEISLKELIETTGTKEIFDFFNLFYDLSSIIWNNEEYSLLVPTASSIPLSGITANSTNLRKFLELHLIPANVTQNLLDCNGSISTKLGTKLNCRKDHLDNVFVSIQGDWTKEVRVLKTGCTTNLKSSCIFLIDKPISLSWLNSEKYHLRLPGIAVGFGVIIGVTIAISLLFCIIITRGGKVKDKNQRGRNDRATTPLIQHSPIIHNPSYSATAHLSPLSQPTFEGSYSVNAIQTPRDIRRVGSDQKGGRSVSTS
Protein: Cyclic nucleotide-gated channel alpha-1 (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated cation channel subunit alpha) (cGMP-gated cation channel alpha-1) (Q62927)
Organism: Rattus norvegicus (Rat)
Function: Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P29973}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cyclic nucleotide-gated channel subunit beta 1.
- Cyclic nucleotide-gated channel alpha-4
- Cyclic nucleotide gated channel subunit beta 3
- PEX5-related protein
- Calmodulin-1
- Calmodulin-like protein 4
- Calmodulin-like protein 3
- Cyclic nucleotide-gated channel alpha-2
- Guanylyl cyclase-activating protein 2
- G protein subunit alpha transducin 1
Sequence:
MKTNIINTWHSFVNIPNVVVPAIEKEIRRMENGACSSFSDNDNGSLSEESENEDSLFRSNSYRRRGPSQREHYLPGTMALFNVNNSSNKDQDPKEKKKKKKEKKSKADDKKESKKDPEKKKKKEKEKEKKKEEKPKEKKEEEKKEVVVIDPSGNMYYNWLFCITLPVMYNWTMIIARACFDELQSDYLEYWLIFDYVSDVVYLADMFVRTRTGYLEQGLLVKDELKLIEKYKANLQFKLDVLSVIPTDLLYFKFGWNYPEIRLNRLLRISRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVYYSISKAIGFGNDTWVYPDVNDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVLDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQSRVDAIKQYMNFRNVSKDMEKRVIKWFDYLWTNKKTVDEREVLRYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGRQILMKDGLLDINIANLGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIETEFSALEEPGGESEPTESLQG
Protein: Photosystem I reaction center subunit IX (PSI-J) (P0C373)
Organism: Oryza sativa (Rice)
Function: May help in the organization of the PsaE and PsaF subunits.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MRDIKTYLSVAPVLSTLWFGALAGLLIEINRLFPDALSFPFFSF
Protein: Myb-like protein C (Q54TN2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Transcription activator required for the culmination, at the time of the fruiting body formation. Regulates genes involved in the cell differentiation within the fruiting body.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:10331990}.
Interaction partners:
- Myb domain-containing protein
- nicotinamidase
Sequence:
MTMINPLSYPVPSQYSYTYNNNNNNSNNSSNNNSNNNSNNNNNNNNNCGVPNVSYGSNLNQQSMAQDLRVPEQYSISSPSPKKRPFNSTMTTSPPTPTLLSNSPYIHGSHIVPQYSPQLQNVYNTPHQSSHSIHQPPQQTPNIFNNNNNNNNNNEKSNNQNFGNTLFNSITNNSSNSSNSLIQQNNLTNNGSSSSSSSSSSTNFNQNNNFINSSNDSIYNSNICSFYGNTSSSSSSSLNGIESPPSVELMDDDIEDQLREYISPVIWGMMDNYAREQFYNAIVEFINEEISFRSLLLELRVIAVMDVNYKSIFQFLVDLFLSIEPNQKMVNYLRDNGVEENEFNIDLKSLELSSDNDSNQKKKRERIRKSVSRGLRNPPNKWAKEESQKLIQLVHEHGDKQWKKIAHQIGGGKTGAQCAQHWKRVLCPAIRKGSWDEDEESKLFNLVEKHGQSWKNVASEIRTRTDIQCRYQYFKSCMSREVQWSSREDEILQKKVSENNQQDGTININNTRDISWMDVSKAMARGRQTKIPRTALECKTRYFQLNFGGAPIQIVVPHNDDHLNNPHSPLNSLLQDQNCY
Protein: Paraflagellar rod component (Q38BF2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPKTAVLTVSAAVAASTEKNGYTPLYGILNDLLLEASDKPVKPVTCMPAKGSLRTRQMVRQLKGISSLEDLAAFEEELRGVVTCQESRCRVKMQKAFLTGQYIAEEYSLLCEEEEQCRNLLWLASVSEVGKRAAFFKVVWDEMYSRYLAYNVFARERIENLYGHFLGKMAAVEADRRRELIELEGMCRKEVTRRRFLEASRHIGMELLFQQSYRVSFWARCRSDNFKRDIVLLDAEEERERCSLERLSLQNLAILANELENSASRLMVTSVMRASLIRRKLVDDERMREVARLLLNVPIREMDLRAVLERYEMEKRQEIRVGFYLGWRELLNQALKPGDAADIVYRLEWYERMCVFDQWRHGFHAIGECHNREKRQIEKFEAEHDEFYYDVVHKLRELWAEESVEYTQLKNMYHSFVWSKRMMESAMIVESEEECCRKRLIEAEIEEAMNLMMFSHLQLCELTAAGRAAAIMEVEASCWESMVRSSYATLGTQLCEKLLNDEENERIAIISEARSAWSVIVLQEAAPSSSPVDDEPVQPVYAGPDPKLVEEWYRRQYSDQWALLEREKCRRKEVVVSESYGRRWVYANILSDVEQWNRMDIAVEFQRGLCGIALEKLVDVEQFVRLDLGTGAQQRWKFLTKSFRYSRPYLLSCEVDELDGRLSIITEAETTIGALFISRGGYRPVKYCSEELWSTRSITQYMSLEELLQRLSDELVHTVEPEGRRKTAACETNERLLLMLMREESVCRCHIHKCVEDSYEALRRLFDRIISREDEWQQRSAHKEPEVERTGVEALMDYFRRQEESFVTKREAQRQRSRQLFGSLFKEFYWGRDAIIVEELVGRDVLRNFVHQRSLSPPVLIREAATQVIVRLYNVALVTNDLAGSLKVAMYGSEEEKGVTCRLSETQTLFSAGAFFRICFPETQLEWSTPLTNESKVLFFRIGADGSDDVVATASLLLRAEAMRRNNTTSVHSIPLDQQNGKMNVIVYIM
Protein: Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase) (Q05117)
Organism: Mus musculus (Mouse)
Function: May play a role in the process of bone resorption. The osteoclastic trap acts on nucleotide tri- and diphosphates with higher affinity, compared with other substrates.
Subcellular location: Lysosome.
Interaction partners:
- Lysosomal acid phosphatase
- Riboflavin kinase
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- Flavin reductase
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
- FAD synthase
- Nuclear factor of activated T-cells, cytoplasmic 1
- Tumor necrosis factor ligand superfamily member 11
- Cathepsin K
- Dendritic cell-specific transmembrane protein
Sequence:
MDSWVVLLGLQIIWLPLLTHGTAPTPTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQTMGADFIMSLGDNFYFTGVHDASDKRFQETFEDVFSDRALRNIPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPYYRLRFKIPRTNITVAIFMLDTVMLCGNSDDFASQQPKMPRDLGVARTQLSWLKKQLAAAKEDYVLVAGHYPIWSIAEHGPTRCLVKNLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSVRHQRKVPNGYLRFHYGSEDSLGGFTHVEISPKEMTIIYVEASGKSLFKTSLPRRPRP