Protein: Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)] (P11029)
Organism: Gallus gallus (Chicken)
Function: Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Subcellular location: Cytoplasm.
Interaction partners:
- Fatty acid synthase S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; 3-oxoacyl-[acyl-carrier-protein] synthase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Enoyl-[acyl-carrier-protein] reductase; Acyl-[acyl-carrier-protein] hydrolase]
- ATP-citrate synthase
- Acyl-CoA synthetase short chain family member 2.
- Trifunctional purine biosynthetic protein adenosine-3
- Trifunctional purine biosynthetic protein adenosine-3
- Uncharacterized protein
- Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
- Acetyl-coenzyme A synthetase
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- Uncharacterized protein
Sequence:
MEESSQPAKPLEMNPHSRFIIGSVSEDNSEDETSSLVKLDLLEEKERSLSPVSVCSDSLSDLGLPSAQDGLANHMRPSMSGLHLVKQGRDRKKVDVQRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLHKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWNGSGLRVDWQENDLQKRILNVPQELYEKGYVKDADDGLRAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPASIATSVVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLHRIKDIRVMYGVSPWGDGSIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQQNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSFRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGRKYVLKVTRQSPNSYVVIMNSSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSILRSPSAGKLIQYVVEDGGHVFAGQCFAEIEVMKMVMTLTAGESGCIHYVKRPGAVLDPGCVIAKLQLDDPSRVQQAELHTGTLPQIQSTALRGEKLHRIFHYVLDNLVNVMNGYCLPEPYFSSKVKGWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLKVETQFQHGHYDKCVFALREENKSDMNAVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELINILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRMSFSSNLNHYGMVHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMSCFCDSPPQSPTFPEAGHASLYDEDKAAREEPIHILNVAIKTDGDVDDDGLAAMFREFTQSKKSVLIEHGIRRLTFLVAQKREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTGQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTSYVYDIPEMFRQSLIKLWDSMNEHAFLPTPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKTPEYPEGRDIIVIGNDITYRIGSFGPQEDVLFLRASELARTHGIPRIYVAANSGARIGLAEEIRHMFHVAWEDPDDPYKGYKYLYLTPQDYKKVSALNSVHCEHVEDNGESRYKITDIIGKEDGLGIENLRGSGMIAGESSLAYESIITINLVTCRAIGIGAYLVRLGQRTIQVENSHIILTGCGALNKVLGREVYTSNNQLGGIQIMHNNGVTHGTVCDDFEGVYTILLWLSYMPKSVYSPVPILKVKDPIDRTIDFVPTKTPYDPRWMLAGRPNPSQKGQWQSGFFDNGSFLEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTAQAINDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLREYRQPVLIYIPPQAELRGGSWAVIDPTINPRHMEMYADRESRGGILEPEGTVEIKFRRKDLVKTMRRVDPVYMRLAERLGTPELSAADRKDLESKLKEREEFLIPIYHQVAMQFADLHDTPGRMQEKGAITDILDWKTSRTFFYWRLRRLLLEDVVKKKIHDANPELTDGQIQAMLRRWFVEVEGTVKAYLWDSNKDLVEWLEKQLMEEEGVRSVVDENIKYISRDYILKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEIVRILSTMDSPSST