wanglab/gogpt-training-data huggingface dataset:
Protein: RNA-binding motif protein 25 (Q8VY15)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Negative regulator of responses to abscisic acid (ABA), including in early development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00627, ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:26404089}.
Interaction partners:
- At2g29210/F16P2.41
- SART-1 family protein DOT2
- Nuclear protein-like
- Tetratricopeptide repeat
- AT5g17440/K3M16_10
- Arginine-aspartate-rich RNA binding protein-like
- U1 small nuclear ribonucleoprotein C
- LUC7 related protein
- U2 small nuclear ribonucleoprotein A'
- Nuclear cap-binding protein subunit 1
Sequence:
MADESSSPATGDPNSQKPESTTPISIPNPNPNPSLTPPPPQQHSQPPVAPLVPPGPPYAPPAQIPSSLLPTNLPPPPPFRPGMQFTPVANFQNPSSGVPPPGSMPQYQPQPGMRPFQPMANGYPGIHGVAPPGAMPPHGLLRYPSPYPTMVRPGFIMRPPGTIGAVQLAPRPLIPGMPGLRPVMPPMVRPASLPFVTPAEKPQTTIYIGKIATVENDFMMSILEFCGHVKSCLRAEDPTTKKPKGFGFYEFESAEGILRAIRLLTQRTIDGQELLVNVNQATKEYLLKYVEKKIETAKKAKESQGTKENQAEGPESEQDKLESADNETGKDGESKIKENIDIANSAVLTDEEREADREAMEKIETAIEERLKSNPLPPPPPPPADGSGMEFAFKSKDGDSNTDVARSDAAANDVETSGEHNRPDTSSPDWSKRNDRRSRERGEKEQEMDRYEREAERERSRKEREQRRKLEDAERAYQTRLRQWERREREKEKERQYEKEKEKEKERKRKKEIRYEEEEEEDDDDSRRRWHRAALDERRRRQLREKEDDLADRLKEEEEVAEAKRSAEEQNLQQQQLDALRILSGQAAIGSETVQTSPIENDHKATLQTVGESANEHHAADFEENGSGNESMAIDNNSGSEAHAPSKKLGFGLVGSGKRTSVPSVFYEEDEDEARKAKKMKPLVPIDYSTEEQEAVAHGGSGNTPPHLALAAEFAKRISSTNPKEETIETEKQRSRRSHDKASHRDRERERERDRDRDRVRDRGDGHSGPTKDAKESGKAKIIDTKFLDAKQLIDTIPKTKEDLFSYEINWAMYDKHQVHERMRPWISKKIMEFLGEEEATLVDFIVSNTQQHVQASQMLELLQSILDEEAEMFVLKMWRMLIFEIKRVEAGVPVKSKA
Protein: Acyltransferase family protein (O53208)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MSAADEQGEERATRKSAPDLRLPGSVAEILASPAGPKVGAFFDLDGTLVAGFTAVILTQERLRRRDMGVGELLGMVQAGLNHTLGRIEFEDLIGKAAAALAGRLLTDLEEIGERLFAQRIESRIYPEMRELVRAHVARGHTVVLSSSALTIQVGPVARFLGINNMLTNKFETNEDGILTGGVLKPILWCPGKATAVQRFAAEHDIDLKDSYFYADGDEDVALMYLVGNPRPTNPEGKMAAVAKRRGWPILKFNSRGGVGIRRQLRTLAGLSTIVPVAAGAVGIGVLTGSRRRGVNFFTSTFSQLLLATSGVHLNVIGKENLTAQRPAVFIFNHRNQVDPVIAGALVRDNWVGVGKKELASDPIMGTLGKLLDGVFIDRDDPVAAVETLHTVEERARNGLSIVIAPEGTRLDTTEVGSFKKGPFRIAMAAKIPIVPIVIRNAEIVASRNSTTINPGTVDVAVFPPIPVDDWTLDALPDRIAEVRQLYLDTLADWPVDGLPAVDLYAEQKAARKARAQVAKATAKRVPAKKAPAKSAANKGAAATKAATKKASPKAKPSESKIAGKDGEASASPSSSAKGRS
Protein: Probable LRR receptor-like serine/threonine-protein kinase At5g37450 (EC 2.7.11.1) (C0LGU1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Glutamate receptor 1.2
Sequence:
MKEMMGVVGIILVVSSCCLSLLDAQEITHPTDVSALQYVHRKLKDPLNHLQDWKKTDPCASNWTGVICIPDPSDGFLHVKELRLLNMNLTGQLAPELGLLSNLTILNFMWNDLTGQIPPELGNLTHLIFLLLSGNQLTGSLPQELGSLSNLLILQIDYNEISGKLPTSLANLKKLKHFHMNNNSITGQIPPEYSTLTNVLHFLMDNNKLTGNLPPELAQMPSLRILQLDGSNFDGTEIPSSYGSIPNLVKLSLRNCNLEGPIPDLSKSLVLYYLDISSNKLTGEIPKNKFSANITTINLYNNLLSGSIPSNFSGLPRLQRLQVQNNNLSGEIPVIWENRILKAEEKLILDLRNNMFSNVSSVLLNPPSNVTVKLYGNPVCANVNAGKLADLCGISTLEVESPATSSETISTGDCKRQSCPVSENYDYVIGSPVACFCAAPLGIDLRLRSPSFSDFRPYKVSYMLDVASPKNLGINPYQISIDTFAWQSGPRLFMNMKIFPEYSELNSKFNSTEVQRIVDFFATFTLNTDDSLGPYEIISINTGAYKDVTIIFPKKSGMSIGVSVGIIIGAIAFFLVLSSLALVFFIKRSKRKRKTREVDMEQEHPLPKPPMNMESVKGYNFTELDSATSSFSDLSQIGRGGYGKVYKGHLPGGLVVAVKRAEQGSLQGQKEFFTEIELLSRLHHRNLVSLLGYCDQKGEQMLVYEYMPNGSLQDALSARFRQPLSLALRLRIALGSARGILYLHTEADPPIIHRDIKPSNILLDSKMNPKVADFGISKLIALDGGGVQRDHVTTIVKGTPGYVDPEYYLSHRLTEKSDVYSLGIVFLEILTGMRPISHGRNIVREVNEACDAGMMMSVIDRSMGQYSEECVKRFMELAIRCCQDNPEARPWMLEIVRELENIYGLIPKEEKPYSSPSVQSSASGMSGFAVASPRSSYTTFSEFTANQLVSGVIPSIAPR
Protein: Small nuclear ribonucleoprotein-associated protein (Q9SUN5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR037187}.
Interaction partners:
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein SmD1b
- U1 small nuclear ribonucleoprotein C
- Small nuclear ribonucleoprotein SmD3b
- U1 small nuclear ribonucleoprotein A
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein SmD3a
- Small nuclear ribonucleoprotein SmD1a
- Small nuclear ribonucleoprotein E
- Probable small nuclear ribonucleoprotein F
Sequence:
MSMSKSSKMLQFINYRMRVTIQDGRQLVGKFMAFDRHMNLVLGDCEEFRKLPPAKGKKINEEREDRRTLGLVLLRGEEVISMTVEGPPPPEESRAKAGSAAAVAGPGIGRAAGRGVPTGPLVQAQPGLSGPVRGVGGPAPGMMQPQISRPPQLSAPPIIRPPGQMLPPPPFGGQGPPMGRGPPPPYGMRPPPQQFSGPPPPQYGQRPMIPPPGGMMRGPPPPPHGMQGPPPPRPGMPPAPGGFAPPRPGMPPHNQQQ
Protein: Abi3bp protein (B2RWZ0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLSSLGCLLLCGSIALALGNAQKLPKGKKPSLKVHINTTSDSILLKFLRPNANVKLEGFLLGYGSNVSPNQYFPLPTEGKFTEAVVDAEPKYLIVVRPAPPPSQKKSCSGKSRPRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPSDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPNTVYEFGVKDNIEGGIWSKIFNHKTIVGSKNKVNGKIQSTYDQVHSVPVPRKLIPLTIIKQVIQNVTHRASTKSPDKTPFGGTILVHLIIPGLNESTVKLPTSIMLEISDALKAQLAKNETLALPAESKTPEVEKLAGQPVTAPRQTTSMPPKLKTPHSRMPAKEPVPKEPLHTTSKPKMPPSPEVADTTSAPLETRGIPLIPVISPRPSQEELQTAMEETDQSTQELFTTKIPQTTELAKTTQAPHRLHTAPVRPRIPGRPHGRPALNKTTTRPDKTKPRGTSHKNGVGTGTKQAPKPPSPGRNASVDSHATRKPGSVSGTRRPPIPHRHSSTRPVSQERRPLPPNNVTGKPGRAGIVSSSRVTSPPLKATLHPIGTATARPGAEQKEPTAPASEEEFGTTTDFSSSPTKETDPLGKPRFIGPHVRYIPKPENKPCSITDSVRRFPTEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQITNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPISAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLTSEQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW
Protein: A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) (Q8TE60)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
Sequence:
MECALLLACAFPAAGSGPPRGLAGLGRVAKALQLCCLCCASVAAALASDSSSGASGLNDDYVFVTPVEVDSAGSYISHDILHNGRKKRSAQNARSSLHYRFSAFGQELHLELKPSAILSSHFIVQVLGKDGASETQKPEVQQCFYQGFIRNDSSSSVAVSTCAGLSGLIRTRKNEFLISPLPQLLAQEHNYSSPAGHHPHVLYKRTAEEKIQRYRGYPGSGRNYPGYSPSHIPHASQSRETEYHHRRLQKQHFCGRRKKYAPKPPTEDTYLRFDEYGSSGRPRRSAGKSQKGLNVETLVVADKKMVEKHGKGNVTTYILTVMNMVSGLFKDGTIGSDINVVVVSLILLEQEPGGLLINHHADQSLNSFCQWQSALIGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHDGEGNPCRKAEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQAGQYKYPDKLPGQIYDADTQCKWQFGAKAKLCSLGFVKDICKSLWCHRVGHRCETKFMPAAEGTVCGLSMWCRQGQCVKFGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCNNPKPQYGGLFCPGSSRIYQLCNINPCNENSLDFRAQQCAEYNSKPFRGWFYQWKPYTKVEEEDRCKLYCKAENFEFFFAMSGKVKDGTPCSPNKNDVCIDGVCELVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLNQHKANEYYPVVLIPAGARSIEIQELQVSSSYLAVRSLSQKYYLTGGWSIDWPGEFPFAGTTFEYQRSFNRPERLYAPGPTNETLVFEILMQGKNPGIAWKYALPKVMNGTPPATKRPAYTWSIVQSECSVSCGGGYINVKAICLRDQNTQVNSSFCSAKTKPVTEPKICNAFSCPAYWMPGEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRLQWVASSWSECSATCGLGVRKREMKCSEKGFQGKLITFPERRCRNIKKPNLDLEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPEKREDPSCVDFFNWCHLVPQHGVCNHKFYGKQCCKSCTRKI
Protein: Trophinin (E9Q098)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDRRNDHGHRVPTFQGPLPPAGSLGLPFSPDVQSETTEKDPPIASRSKKNKNKKNSIKPMDKTTPAPPPVPSANDNASNKPKVTLQALNLPMFTQISQASATTEAPNIQASVTSQTQKAKTMRVTPKVSLTGSEDATTQLKPPLQALNLPVTTPTIQTPVANESANSLASTAVNKSKKASTANNAANKTVPSAAEISLASAATHTVTTQGQAAKETGSIQTIAATARSKKNSKGKRTPAKTTNTDNEYVEASNAIEASSRQIGASGRQTEASNRQIEASSRQTEASNRQTEASSRQTEASSRQTETSNRQIGASNRQIMASNRQIGASNRQIEASNRQIGASNRQTEVSSRQIEASNRQIGASNRQTEASNRQIGASNRQTEASNRQIGASNRQTDASNRQTDASNRQTEASSRQTEASSRQTEASSRQTEASSRQIEASAAAVRPKKPRGKKGNNKGSNSASEPSEAPPAIQTVTNHALSVTVRIRRGSRARKAANKNRATESQAQIAEQGAQASEASISALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHPNGEERTGNNYRRIPWGRRLPPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLKDVIQEYEDYFPEIIERASYALEKMFRVNLKEIDKQNNLYILISTQESSAGIMGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLHPGVKHSLFGEVKKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACKVQKKDPKDWAAQYREAVEMDIQAAAVAVAEAKARAEACSPCLQITLTATILPMEPMCSFGIVVHAAA
Protein: Achaete-scute complex protein T5 (Protein achaete) (P10083)
Organism: Drosophila melanogaster (Fruit fly)
Function: AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Interaction partners:
- Achaete-scute complex protein T4
- Protein extra-macrochaetae
- Protein atonal
- Protein daughterless
- Achaete-scute complex protein T3
- Zinc finger protein sens
- Enhancer of split m8 protein
- Sphingosine-1-phosphate lyase
- Beadex, isoform D
- Protein hairy
Sequence:
MALGSENHSVFNDDEESSSAFNGPSVIRRNARERNRVKQVNNGFSQLRQHIPAAVIADLSNGRRGIGPGANKKLSKVSTLKMAVEYIRRLQKVLHENDQQKQKQLHLQQQHLHFQQQQQHQHLYAWHQELQLQSPTGSTSSCNSISSYCKPATSTIPGATPPNNFHTKLEASFEDYRNNSCSSGTEDEDILDYISLWQDDL
Protein: Pre-mRNA-processing factor 19 homolog 1 (EC 2.3.2.-) (MOS4-associated complex protein 3A) (MAC protein 3A) (Plant U-box protein 59) (U-box domain-containing protein 59) (Q94BR4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair (By similarity). Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity.
Subcellular location: Nucleus {ECO:0000269|PubMed:19629177}.
Interaction partners:
- Cell division cycle 5-like protein
- Pre-mRNA-processing-splicing factor 8A
- Pre-mRNA-splicing factor SPF27 homolog
- DExH-box ATP-dependent RNA helicase DExH12
- Protein pleiotropic regulatory locus 1
- Tetratricopeptide repeat
- AT3G18790 protein
- Cwf15 / Cwc15 cell cycle control family protein
- Protein pleiotropic regulator PRL2
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
Sequence:
MNCAISGEVPEEPVVSKKSGLLYEKRLIQTHISDYGKCPVTGEPHTLDDIVPIKTGKIVKPKPLHTASIPGLLGTFQTEWDSLMLSNFALEQQLHTARQELSHALYQHDAACRVIARLKKERDESRQLLAEAERQLPAAPEVATSNAALSNGKRGIDDGEQGPNAKKMRLGISAEVITELTDCNAALSQQRKKRQIPKTLASVDALEKFTQLSSHPLHKTNKPGIFSMDILHSKDVIATGGIDTTAVLFDRPSGQILSTLTGHSKKVTSIKFVGDTDLVLTASSDKTVRIWGCSEDGNYTSRHTLKDHSAEVRAVTVHATNKYFVSASLDSTWCFYDLSSGLCLAQVTDASENDVNYTAAAFHPDGLILGTGTAQSIVKIWDVKSQANVAKFGGHNGEITSISFSENGYFLATAALDGVRLWDLRKLKNFRTFDFPDANSVEFDHSGSYLGIAASDIRVFQAASVKAEWNPIKTLPDLSGTGKATSVKFGLDSKYIAVGSMDRNLRIFGLPDDDNTEDSAQDS
Protein: Homeodomain protein EPX (Q9Z2U3)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
FRVAPRSSHSSQPYLGSKPLFFFFFLFSFPPSPDPQPSLSSTLLEGADYQENAESETTFYSDFGASPKEEEVEMENSLFNSMFLEEANYQEPEGFEPSRGEAAAPVAEAPQAWNGNENLGGGFLESNAQLGEADAAPVRQSLMRPLMQPVAQSSPQPLPANPLQAPQQPEEQEEEEEEQPGEEQPQQEPKPRRYRICFTPIQLQELEAFFQRVQYPDLFARVELARRLGLPEPRVQVWFQNRRAKWRRLRRAQAFRNMVPVAMSPPVGVYLDDHYGPIPIVEVIWKCYPMVPRPMHPQMMPLPPRPPPGFRMPPPFRPPPLPPFPWPPVPPDAHIPNAAREYNPFPFPFPFPFPFPNPFPNPNPNPNPNPNPNPNPNQNFAGPRYRY
Protein: Candida glabrata strain CBS138 chromosome M complete sequence (Q6FJT0)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- 60S ribosomal protein L36
- Small ribosomal subunit protein eS6
- L23
- Candida glabrata strain CBS138 chromosome M complete sequence
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein eL32
- 60S acidic ribosomal protein P0
- L21
- Candida glabrata strain CBS138 chromosome A complete sequence
- Small ribosomal subunit protein bS6m
Sequence:
MAPSAKASAAKKAVVKGTNGKKALKTRTSATFRLPKTLKLARSPKYASKSVPHYNRLDSYKVIEHPITSETAMKKVEDGNILVFQVSLKANKHQIKKAVKELYEVDVMKVNTLITAKGNKKAFVRLTADYDALDIANRIGYI
Protein: Clarin-1 (Usher syndrome type-3 protein) (P58418)
Organism: Homo sapiens (Human)
Function: May have a role in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in analogous synapses within the retina.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21310491}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Unconventional myosin-VIIa
- Harmonin
- pre-mRNA splicing regulator USH1G
- Whirlin
- Usherin
- Protocadherin-15
- Adhesion G-protein coupled receptor V1
- Cadherin-23
- Calcium and integrin-binding family member 2
- Voltage-dependent calcium channel gamma-2 subunit
Sequence:
MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFWVIFFCFFVHFLNGLLIRLAGFQFPFAKSKDAETTNVAADLMY
Protein: Calcineurin b subunit (Protein phosphatase 2b regulatory subunit)-like protein (Calcium-binding EF-hand family protein) (Q9LS47)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- NAD
- At2g22080
- Peptidyl-prolyl cis-trans isomerase FKBP12
- Cinnamoyl-CoA reductase-like protein
- Methylsterol monooxygenase 1-1
- glucan endo-1,3-beta-D-glucosidase
- AT-hook motif nuclear-localized protein 16
- Beta-glucosidase 20
- Probable calcium-binding protein CML29
Sequence:
MGNTSSMLTQYDIEEVQSHCHDLFEQQEILSLYQRFCQLDRNAKGFISADEFLSVPEFAMNPLSQRLLKMVDGLNFKDFVAFLSAFSAKASLRQKVQLIFKVYDSDCNGKVSFKDIMEVLRDLSGSFMSDEQREQVLSQVLKESGYTSDSFLTLEDFIKIFGSSRPEMDVEIPVD
Protein: Zinc finger protein 844 (Q08AG5)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Zinc finger protein 347
Sequence:
MDLVAFEDVAVNFTQEEWSLLDPSQKNLYREVMQETLRNLASIGEKWKDQNIEDQYKNPRNNLRSLLGERVDENTEENHCGETSSQIPDDTLNKKTSPGVKSCESSVCGEVFVGHSSLNRHIRADTAHKPSEYQEYGQEPYKCQQRKKAFRCHPSFQMQEKAHTGEKLYDCKECGKTFISHSSIQRHMIMHNGDGTYKCKFCGKACPCLSIYLIHERVHTGEKPYKCKQCGKAFSYSTSLQIHERTHTGEKPYECKECGKAFGSPNSLYEHRRTHTGEKPYECKQCGKAFRWFHSFQIHERTHSEEKAYECTKCGKAFKCPSYLCRHEVTHSGKKPCECKQCGKALSYLNFQRHMKMHTRMRPYKCKTVEKPLILPVRFEDMKELTLERNLMNASTVVKPSIVPVPFTIMKGLTLERNPMNVSSVVKPSFLPLPFDIMKGLTLERNRMSVSNVGKPSDLPHTFKCMEGLTLKRNPMNVSSVVKPSFFPLPFDIMKGLTLERNPMSVSNVGKPSHLPHTFKCMKGLTLESNCMNLNNVKKPLDLSETFKFMKRHTLERNPIRNMEKHSTISLPFKYMQQCTEDRMPMNVKSVTKHSYLPRSFEYMQEHTLERNPMNVRNAEKRSIIFLLCVYTKGCTLERNHINVRIVGKHSVCLVPFVDIKGLTLE
Protein: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (F2Z2I2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEAAKSTTLC
Protein: Endoribonuclease MazF9 (EC 3.1.-.-) (Toxin MazF9) (mRNA interferase MazF-mt1) (P71650)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli and M.smegmatis inhibits cell growth and colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE9. Acts as an mRNA interferase, specifically cleaving between U and C in UAC sequences. May cleave its cognate antitoxin's gene. In E.coli expression with non-cognate antitoxins VapB27 and VapB40 partially neutralizes the toxin.
Interaction partners:
- Antitoxin MazE9
- Endoribonuclease MazF4
- Probable endoribonuclease MazF5
- Antitoxin MazE6
- Endoribonuclease MazF3
- Antitoxin MazE7
Sequence:
MMRRGEIWQVDLDPARGSEANNQRPAVVVSNDRANATATRLGRGVITVVPVTSNIAKVYPFQVLLSATTTGLQVDCKAQAEQIRSIATERLLRPIGRVSAAELAQLDEALKLHLDLWS
Protein: Uncharacterized protein, isoform F (M9PEU6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}.
Interaction partners:
Sequence:
MDSLKLPKANSATSSASGSNSNLSGSTSASASAATSPTSSGTAVGGILSGAPKSPPGLGSSTPISVRFNANEESLDDILQSFHHSKHSPSGGASGGGDASPTSNLLGMKNNGLGLVVGNCDSLSSSPSQPQMHAGSASLFGNDEVSLRNNFMQAGGFFNRKRSGSIEGVSPTSSGPSIISTLSTASAAGGGGSSVGGAVAAGDSNSSGGTWRLIKGKVTQTIEEIKSSKLPPTAAIPIIVADPPSTGWSNDPDSDTECLTVNTSISEELPLDLEHKQNSDSDVEAELLQHDSISLGSGDVPTVAATGHSERSRLRRGLAHIRSKVKAKQQAAPAMNKKDVSPSGSTVPATSVRTGFLRRRNVVEAGSEPSTSQQAEIAIASGKVKKRGILLARKDVEIESGVEVLEDMIPSTAVHIDHSKDVANKRAEEVTDAGADADSRASLTLPVAPGFSTLASSYVEKESGVRDTRSRISFFSNLSMLSVSQWREKHQGATAFALPVLLSVLLILLMILPVPDFLRGVFATLLFFTVMDCCGGHLRALLEDFMLTTHPERVAFAIPNYKFMPICEIPAVEEHKTIKTYAGWMNEINSYDPNTFSFSLTRAVYVRLDGSILKMSGTNARIPKRRMWNEPPIDRHKIPFTDHRSYDLRDCRIELLPLGLANKRFFNRKYPIQLIIKSNRDVPDEQSSVESQSEATVKTDAKEAKAASSSGTTPPGGEEEKLVDFAGTVMQADLQQLRNTVNPDKELNDITVPCGDEVRLLLFSRCDREKEDWYRRFTNASRGLVHEQDLQVPMARFVEDSDLQAAAARQALLLVTGMGKAGVKSEDEISAGKGNDETDQQTPDGQFETITEEDLLDTPKEESFDGMIMSANVARNSPDYVRFMAVYQSRRAKRQEDELWKGIDQSLFLGPSGSIVWANVLLGRCLYSWLHDAMLHEKLKEVLQKKLNSIKLPSFMEEVIITNIYLGESPLLCHRVSQPMLDERGVWIDADVTYEGLAHITVTTKLNLLRIRSKTKSPMATDNVPTTSMLPEQSQDLRSLSEVNSENVIYDSDAESSGGSSTESESPPPGNAPENAAGTEFFQNSPGNARRIFKIVDRIAASNLFQYATELPYVQRAMENMNANITLRVDLKGLVARGTLNVPPPPSDRVWVSFRGPPRLWISTKPQVGDKSVDWSIVTNVIESKLCEAVNKFLVYPNMVDFSIPFLSNPNFDEDQGNAAN
Protein: Branched-chain amino acid ABC transporter, periplasmic substrate-binding protein (Q5LSQ6)
Organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Interaction partners:
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein, putative
- Branched-chain amino acid ABC transporter, permease protein
- Regulatory protein, putative
- Nif-specific regulatory protein
- Branched-chain amino acid ABC transporter, permease/ATP-binding protein
- Branched-chain amino acid ABC transporter, permease protein
Sequence:
MKPAPMRKRFSAPREETSMNFLKTTLASSVVFAALCNAAMAAEDKIKVGVLHSLSGTMAISETTLKDTMLMLIEQQNAKGGLLGKQLEAVVVDPASDWPLFAEKARELLTVHEVDVIFGNWTSVSRKSVLPVIEELNGLLFYPVQYEGEESSKNVFYTGAAPNQQAIPATDYFLEELGVEKFALLGTDYVYPRTTNNILESYLKQKGIAEADIFVNYTPFGHSDWSKIVADVVALGADGKKVGVISTINGDANIGFYKELAAAGISADDIPVVAFSVGEEELAGLDTSNLVGHLAAWNYFQSAESDVNAEFVKSWKATMGEERVTNDPMEAHYIGFNMWVNAATEAGSTDVDAVRAKMYGQEFPNLTGGTAVMLPNHHLTKPVLIGEIQADGQFDIISQTAEVPGDAWTDFLPESAVLMSDWKELGCGMYNTETKTCVQTLSNY
Protein: Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2) (Q8TDN2)
Organism: Homo sapiens (Human)
Function: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
Subcellular location: Cell membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
Interaction partners:
- Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
- Ubiquitin-like protein FUBI
- Multiple PDZ domain protein
- E3 ubiquitin-protein ligase LNX
Sequence:
MLKQSERRRSWSYRPWNTTENEGSQHRRSICSLGARSGSQASIHGWTEGNYNYYIEEDEDGEEEDQWKDDLAEEDQQAGEVTTAKPEGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTTIRRERGEVNFMQRARKKIAECLLGSNPQLTPRQEN
Protein: Low molecular weight protein antigen 6 (CFP-6) (P9WIR1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Secreted {ECO:0000269|PubMed:10812229}.
Interaction partners:
- Possible conserved membrane protein
- Uncharacterized protein Rv1109c
- Conserved protein
- Conserved alanine valine rich protein
- Anti-sigma-E factor RseA
- Probable conserved transmembrane protein
- Possible conserved secreted protein
- Uncharacterized protein Rv0010c
- Conserved protein
- Probable conserved lipoprotein LppL
Sequence:
MAHFAVGFLTLGLLVPVLTWPVSAPLLVIPVALSASIIRLRTLADERGVTVRTLVGSRAVRWDDIDGLRFHRGSWARATLKDGTELRLPAVTFATLPHLTEASSGRVPNPYR
Protein: Fanconi anemia group E protein (Protein FACE) (Q9HB96)
Organism: Homo sapiens (Human)
Function: As part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. Required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.
Subcellular location: Nucleus {ECO:0000269|PubMed:12093742, ECO:0000269|PubMed:17296736}.
Interaction partners:
- Fanconi anemia group M protein
- Fanconi anemia group B protein
- Fanconi anemia group C protein
- Centromere protein X
- Centromere protein S
- Fanconi anemia group F protein
- Fanconi anemia core complex-associated protein 100
- Fanconi anemia group G protein
- Fanconi anemia group D2 protein
- Fanconi anemia group A protein
Sequence:
MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKGLAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP
Protein: Uncharacterized protein (Q386V8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGLLTRYYEKLAEQGRLEQLIVFGMYDERVYEVIDRHKLAGSITALLPSSQAAAFLSRGMAYDCVNEEVLRNFIKICMMLSTYKTVEEGASLAELIGSCGVPEHYRMSLFNFSETYRHMILSKSYFPQRAVLKLLSYIFCDDVLTDAVAQLQYKSDILNHVNKVYVDTPDFISWRFSVRVLSLAGGYNEDRSDVEYTDALTRLVTRTIPEFIVYFGATFMYAMIRHYPRRVRGITPRWLARQRAVFSAAYCAFLGVFVNSILEYRVHKHRMLYELRKSQECRRRRGAEKRGVDYTPNTYFDSLEGVTRHIYSMQLTTYGASASMLLLSLVPLVPVKFPKWMGDVAWRHPFVPRLFPAILGMHAASRCMVPFVFAPFTIMTALRFNGWSTTLYDRYVELRMRLWHRKVEAVFDTSTDVTDLDVTRESKKKGGLAGN
Protein: SALL4C (Spalt like transcription factor 4) (Q6Y8G5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGRSSLPSTFIRAPPTYVKVEVPGTFVGPSTLSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNNSARRGRKLAIENTMALLGTDGKRVSEIFPKEILAPSVNVDPVVWNQYTSMLNGGLAVKTNEISVIQSGGVPTLPVSLGATSVVNNATVSKMDGSQSGISADVEKPSATDGVPKHQFPHFLEENKIAVS
Protein: Transcription factor E2F2 (E2F-2) (P56931)
Organism: Mus musculus (Mouse)
Function: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.
Subcellular location: Nucleus.
Interaction partners:
- Retinoblastoma-associated protein
- Retinoblastoma-like protein 2
- Transcription factor Dp-2
- Cyclin-A2
- Transcription factor E2F1
- Retinoblastoma-like protein 1
- Cyclin-dependent kinase 2
- Cyclin-A1
- Transcription factor Dp-1
- Transcription factor E2F3
Sequence:
MLRAPRTLAPATAQPTKSLPALNPTELWPSGLSSPQLCPATTATTYYTSLYTQTVPSSVALGTCLDATPHGPEGQIVRCAPAGRLPAKRKLDLEGIGRPTVPEFRTPKGKCIRVDGLPSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKSKNNIQWVGRELFEDPTRPSRQQQLGQELKELMNAEQTLDQLIQSCSLSFKHLTEDNANKKLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRAEENLQIYLKSTQGPIEVYLCPEEGQEPDSPAKEALPSTSALSPIPDCAQPGCSTDSGIAETIEPSVLIPQPIPPPPPPPLPPAPSLVPLEATDNMLELSHPLLQQTEDQFLSPILAANSPLISFSPPLDQDEYLWGMDEGEGISDLFDSYDLGDLLIN