Protein: Dynein heavy chain, putative (Q57VT8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- ODAD1 central coiled coil region domain-containing protein
- Flagellar attachment zone protein 1 conserved domain-containing protein
- C3H1-type domain-containing protein
- Dynein axonemal intermediate chain 4
- Dynein, putative
Sequence:
MQSKRDSSSEFLETLYQSTERGKTVSQTYLAAQVEKEINRTLDPVQLYEFQKPENFRYNLRHGGVPVANKVCDASSLSRERGLNGPGANGDHMEPESVSGVRPFWRTHLDEQDSEILRMIQRAMRPPNKSSVPPVAPDDAAVIRKLKTAEDCITFFAANGSSSHLKYVYLCRAPHVLEFRPYDLCVSPMKRGLEQKEHYIMSATGVVHVRPGHPSEVVSLAEWMRESSLFDVLRKVHFFKTYLVYKAFFRWYKNVRAKDFLNKRRLLSRNLLISKSTFSTPILEVLNASYDLTTHPLVLYEAQGKHDYTIEDFRTQQAKQRQKTSAAFVACMEKIETGVMKLIEVMKSKADVPDINTKEALEQYLLANAIVTGSGSFRSQRKMKSMHDARGEQLQRMRELKRSIVEYSQIDQLIRMVDCVTSETVFRVILSAIKTLYNTLHIQSSQELRSVGFQVLLQPTEDQMLFNPPERAIRTLCTELITECIEVTGSVTRLCSQKRLKGHFTKAPALWVLGGELESDARTLYLQSSILQLVGDDYAQANTKMQAYAVTLPHIHFLEREWSDILAQWEEETGERPLTCSTLFKLYDKIQDAQDTLRVLMASFVGNMLWINAAKLKTEIEPRMRIVRDGIDSTLREITRTAISSLHSYFKQKIQVLNERPGQLSQFAEYVAHYKEVVSETTETEAAVAQADALCDLMDRQQVEFLDDEDKQLRERTLGSVSTAMSLQILFDEARLHAEAFIEENLPFHTQTLEDSVCNVEDECVTIKQILTNSEFVVLTENVEPIIQYLAELNTKLSEIQASETQLTKYAKLFDRPPIDWSTLKEMRSLVFVRREAWTLLDTFMKQREMWFNSPVRELDTAAMEDEVNQLIRRTGALNRQVQEKEYEDEVGQHLLTELQELRAIMPVIHDCGNKHMTDSHWNIVLREATGSDNRYHEGLSLRNLQDLNILEYKEVLSEQVGLATGEWKISNDLDKIKQTWNGISFTTKPYRNRDGVFILDALEDVIQQLDDNQVELQTIMASRFAAPVRDRVEEWIRNLRHVGNVMEEWTNLQKNWMYLEFIFSSDDIKAQLPEESMQFSSVDTLLCLLTMKAHNDKNVYQICTENGVLEQLQQANLNIDYIQKKLEECLETKRAAFPRFYFLSNDELLSILSDVRNPKAVQPHLTKCFDSIASLIFSGDTYSEISGMMSGDGEEVEFEKVVYPIGNVEKWLCQIESMMRASLLMHMRKTVEAYTPEARETWFFNHPAQCIQAVDMVVWTQEVEEAIRAGSLLEYHEHYQQQIFQTVNLVKGSLTKLQRTLVCTLIVLNVHNRDIVYTLHESSVTSLSDFAWAQQLRYYWEATDSVKSGMSVGIHHCDAHLWYGYEYLGNQPRLVITPLTDRAFLTCTSALAMNLGAAPQGPAGTGKTESVKDLGKALARQVVVFNCSDGINYKTMSRMFAGLAQAGAWACFDEFNRIELEVLSVVAQQMLDITSALAQRLESMSFDGHMIKLSRNFGVFITMNPGYAGRTELPDNLKALFRPICMMIPDYALIAEIMFYSEGFKDARTLARKMVQLYKLSSEQLSKQDHYDFGMRAVKSILVLAGGLKRQHPNDDEDMLLIRAMRDANVPKFLRDDTILFMALIKDLFPTVKIEETQSDLLVRYVREDMEKKGLQVVEGLITKTLQLYDTLVVRHGVMLVGQTFSGKSTIMHVVQGALTQIKADGHDPEGNIPLFNTIHIHLLNPKSVTMGELYGQVNEITREWTDGIISNIARTITRVAQELPDRQWIVFDGPVDAIWIENMNTVLDDNKLLCLFNGERIKLPSTATFMFEVQDLAVASPATVSRCGMVFTEPFYVDGGRGWIPLAKSLVTKKASMFPRFRADRVSELLERFLPMSLDFIRKECREWIGSVDAQLAVSCIELLAAFMKTIDEEDLLPPLLRTKEAKPQNDDVYLLPETTYSGVKLVPSEPEEFKAPEIAYEQVSADDETLLDMYFLMSFVWSVGGNLRDDSRERFSAFVKKHFEELLPGKIAADDGNSVYDYVVHKASMRFVTWRHLVPTFCFSPELPYFDLIVPTAETVSVITLFGVLVANSRHVLLNGVTGTGKSLAVMDFVTGTLRGDDPEGPWEYFDTVLSAQSRARDIEDRLDGKLYKLRSNAIGPKPGKRAVFIVDDLNMPALERYGASPPLELLRQLITQGGFYDKRKSPATFKEVHDVVFLTACGVPGGGRNEMTKRLTSRFHLLCQPSFSDHSIRRIFGCILHGFLSAWEQPDVNALSSVLVEAIKECYYLISTEKLPTPKRSHYTFNLRDFSKVVQGIMQVSPTSAPTREILLNVFVHEVSRVFHDRMIDDGDRRWWWKTLSGVSQRVLKMNWDPRLENVIFGDYMRRDRSQYAEIQTGEGLIEVLREYQNGYNIESNGTCELVFFKDAIHHISRICRIFRQPRGHALLVGMGGTGRQSLCKLAAFMCNLAVHEVTITRSFNMAEFRERLKGILMESGCKDNPSVFFLTDNQIVQEEMLEDVNNLLNTGEVPGLMQNEDIDQIVEAVRPLASAAGKKEARNAIFSHFVTLCRNNVHVVLALSPVGEPFRRRLRMFPSLVNCCTIDWFDQWPADALHSVAQHIFSELPLDEEMKNGLIKLCVSIHIDVQNRSEEFFEELHRRNYTTPSSYLELLNCYHQLLSEQEEQTIAQMKRYQAGLDKLQSTQCTVDEMKEQLVQMQPKLLQAAQDTEEIMTKVKLEQESAQVVRTECSKEEEAAMAIRREADGIRAECQAELDKALPILRAAENALAELRPDDIREVKSFQKPAARVVLVLEAVLILLGERDLSWDRAKLVMGRMDFIKDLQNYKKDELTERTIRSIQKYVNNPEFQPQEVAKSSKACKSLSMWVLAINNYYEVVKVVAPKRERLAEAEAKLSVATATLREAQDRLKSIEDKINGLKRDMQENIEKKNKLEADIALTKARLNRSEQLMSGLSREQDRWHSSITFLQDEKLGLPGKVALAAGCIAYLGPFTGPYRKRMLTAWWENCKEFGVPIGNSVFDLTTLVSPAKVSSWSAAGLPQDPVSTENGVIVTKSKRWCLCIDPQGQACAWIRAMERENNLRTIRLSDPSYMRTLENAIRVGLPVLIENVEETVDAALDPVLLRQTYRSQGRLLLKLGDVEIDYDPGFRMYMTSKLPNPHYLPELQIKVTVINFTVTQGGLENQLLTDVVRYECAELEAKASNTQKDISDGKTQLKAIEDRILHLLTSSTGNILDNEPLVRTLSEAKDTSEAVTEALNLAEQTQKDIEVACNRYRPVATRGAVIYTVLSHLARVDHMYQISLDFFKQLFVKSMHRTEKVSDVDERVAILLPAVTLDSYRTVCRGLFERDKPLFVALIFSEIYRQEGIISDAEWEFLLKGSEGRSLVDIDNDSWPVWMTEAAWNELTALSMALPETFGDIKDTIYDNEDDWSTWFESDTAYEWFPSTTQGLTLFQKVLVLKACREDLTSHGLSIVCSHYLGKVFTESPAFDLEACFADSSPTAPIIFVLTAGIDPTVLFTEFAERKGFAEKKLVLSLGQDQGPKAEEMIRRGSKDGWWVYLQNCHVYESWMSTLERCVEKLHISTTLHSDFRLWLTTMPTRSFPVLLLQSGVKVVKEPPKGLKANIRDSFCNEVTPALWDGRPENPTTWRRLLCSLAYFHAVIQERRKFGPLGWNIPYEWNQSDFSASLHTLQVYVPTGVSESVPWSALRYMVGTINYGGRVTDFLDSRALVNILDAFFNENVLQPGQFNITSDGVYCIPEDVESLDAVKEYLADLPAFESPELFGMHSNADIACNRTTARNQLAVMLSVQPRTKGTAGRSPEDKVLEMVSEFQTRLPEAIDKTKAHPDTYQLTEGGVMISLGTVVSQEIDVFNSIIRKLEATLLELKRGIKGEVVMSARLESMFDACLLGQVPQIWHENSYLSRKPLASWFQDTLLRVEFFRDWNDNGMPMSFWISGFFFPQGFLTGVLQAHSRENMIPIDDIRFRTNVTRYEVVEDIVNTPKAGVLIHGLFLEGARFTFEGMSLCESNPRELYTSMPLINLEPQRLKDQDKSKPVYECPVYKTSARAGALSTTGLSTNYVISLDLSPGSSPPEHWIRRGVALLCMLDD