wanglab/gogpt-training-data huggingface dataset:
Protein: Nuclear transport factor 2 (NTF-2) (P61971)
Organism: Mus musculus (Mouse)
Function: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P61970}. Nucleus outer membrane {ECO:0000250|UniProtKB:P61972}. Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P61972}. Nucleus inner membrane {ECO:0000250|UniProtKB:P61972}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:P61970}. Note=At steady state it is essentially nucleoplasmic, enriched in nucleoplasmic foci. {ECO:0000250|UniProtKB:P61970}.
Interaction partners:
- Nuclear pore glycoprotein p62
- GTP-binding nuclear protein Ran
- NTF2-related export protein 1
- Ran-specific GTPase-activating protein
- Nuclear RNA export factor 1
- Fanconi anemia group M protein homolog
- Nuclear pore complex protein Nup54
- Importin subunit alpha-1
- Regulator of chromosome condensation
- NTF2-related export protein 2
Sequence:
MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG
Protein: Orai2 protein (B0BNI3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSAELNVPMDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLETKYQYPQPLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDAKDQPGSHSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHERSLQVV
Protein: Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (Sialyltransferase 8E) (SIAT8-E) (Sialyltransferase St8Sia V) (ST8SiaV) (P70126)
Organism: Mus musculus (Mouse)
Function: Involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, GP1c and GT3 from GD1a, GT1b, GM1b and GD3 respectively.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q6ZXC8}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
- Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
- Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
- Beta-1,4 N-acetylgalactosaminyltransferase 1
- Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2
- Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
- Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
- Acetyl-coenzyme A transporter 1
- Beta-1,3-galactosyltransferase 4
Sequence:
MRYADPSANRDLLGNRTLLFIFICAFALVTLLQQILYSKSYIKRGFQFGWQRGDQQANWTGLFNDSDSPTEQNITGSSSRYFEFYKEPLEFNSTRCLELRQEILEVKVLSMVKQSELFERWKSLQICKWAMDTAEASLFKSTLSRCCNAPSFLFTTQKNTPVETNLRYEVESSGLYHIDQEIFKMFPKEMPYYRSQFKKCAVVGNGGILKNSGCGKEINSADFVFRCNLPPISGIYTTDVGEKTDVVTVNPSIIIDRFHKLEKWRRPFFSVLQRYENASVLLPAFYNVRNTLVSFRVKYMLDDFQSRQPVYFFHPQYLSSVSRYWLSLGVRARRISTGLILVTAALELCEEVHLFGFWAFPMNPSGFFITHHYYDNVKPKPGFHAMPSEIFTFLRMHSRGILRVHTGTCNCC
Protein: Latent membrane protein (Latent signal transducing membrane protein) (Q9WNA9)
Organism: Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Interaction partners:
Sequence:
MNYKKYLWGTWFAALITCCGCLSIMFCLLTINLQNTIFLLSNISVYYQLFCTITNIYVQSKKQRFQASPPIGPSIIVGCIAFASWSFSTQSTLSTVCVCIISLLSIITAILSLGGTLRVVKCTIDSGLLCIVMVLVLIFSMGLQIYNNWTHCQFFLPLWTLLLVFFIHIFATDNGPCLKLAACVFAICGGILKATPAFFCVSHSCLSVIIAGCISCIHIGMTGLFITMKRHWIGSTKGLMSFLLLQGGVLVTLTTTIGILFIKREQDTNNEGSITLLAGCGFLLYCFFCWQSFHKASLSGGFLFLFLAWTCAGCCVKLVLLYTDGWTTGVTSGLICVIVILSTGQAVLVGYLYRESRLVSFNNVTTRLPIYTPHDTPHAHAGRICPDVNHLARRLPPLPSRNVIHSRILSSTTDMALSPVRVCNTEVTTQLEMQQLHSERTVTYASILGDNTPPPTRASACINQSGISNVSNCGVRSLDPPPFQPADEVYEEVLFPTD
Protein: Endonuclease/exonuclease/phosphatase domain-containing protein (Q584E4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- poly
- NOT1
- Cell differentiation protein, putative
- Uncharacterized protein
- NOT2/NOT3/NOT5 C-terminal domain-containing protein
- Probable eukaryotic initiation factor 4A
Sequence:
MARHPNTAIVLQPTNSAIITLDLCLQLGGPSAPLWRKSVARDENEAADRAIERLRILIAQSAGDKKSKKTSREEILKNCQPIEVLGVSSEGEQILNEENGLTKLDTSVSNKEFWRNVRQMLIGSTVVPVKYNVPTITAVVPPSALYVGAPAVCAGITALFTTEVDVQYEWCARAAPKSPAGTGASSDATVRVISTKPVFTPTTRELGESLFLRVLPEPGSDLCTQVELPQVRAEVPPMDRWTQTKQSVEAPSFRMVTYNVLHEEFCSTSSAKKTIYPFATDDILSLEYRQSRIVQELLAYNGDIICLQECGKKVYQQFFSRVMTQYGYEGCYTNKNGGVREGCACFWRRSRFFLQEKDEFPLNWSTMEKEHPALAAEVTRHPELKEALENVTSIGALVLLKDNATNEELVVGNTHLFYHANACHIRLLQVYMLLHKLKSRSDSRRGVVLCGDFNFTHTTGGYKLVTTGRTEASHHSWAKGEVFHWGCDRMLGINAAEGAGGSAEVETGLDVRRGKGESATCASKNNKNDTNNNNESNGNSVDASTSCAATSADTGVASSVKADYRPPFDVFRADMEAPMQFTDAYGVTDPEMPWTNYTMTFREVIDYVFFNPDRLLVVQTIPIPPESELSENVALPNRKYPSDHVALIADLSYK
Protein: CCAAT/enhancer-binding protein gamma (C/EBP gamma) (P26801)
Organism: Rattus norvegicus (Rat)
Function: Transcription factor that binds to the promoter and the enhancer regions of target genes. Binds to the promoter and the enhancer of the alpha-1-fetoprotein gene. Binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene (By similarity). Binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis-acting element in the G-CSF gene promoter (By similarity).
Subcellular location: Nucleus {ECO:0000305|PubMed:1377818}.
Interaction partners:
- CCAAT/enhancer-binding protein beta
- Cyclic AMP-dependent transcription factor ATF-4
- MHC class II transactivator
- Cyclic AMP-responsive element-binding protein 1
- DNA damage-inducible transcript 3 protein
- Forkhead box protein O1
- Protein c-Fos
- Transcription factor Jun
- Hepatocyte nuclear factor 4-alpha
- Peroxisome proliferator-activated receptor gamma
Sequence:
MSKLSQPASTAGVNGISVIHTQAHASGLQQVPQLVPAGPGGGGKAVPPSKQSKKSSPMDRNSDEYRQRRERNNMAVKKSRLKSKQKAQDTLQRVNQLKEENERLEAKIKLLTKELSVLKDLFLEHAHNLADNVQPISTETTVANSDNTGQ
Protein: PIN domain-containing protein (Q381G1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRLPSFTAATSPHPQRIKSPSHRGKSEEVEIVQGGTGCGLLFMQRVPPPTRALPLLVASSGCGTWVDVLSVYKSVTELLSGVYQPTTEELNQGLLKMENSWSASLFYYGIIKGICGQVRPHTRLVGTALERFKRYSNFYAIKRIMEEDVDATTYQGTRSALVYASFTGMWEHAIHLYKKHPGMRQSITDTRSLINILSSNGRWGEAIKVLHQQPLMSMAPSNIKPIVRALGVAGKYDKMLRLVASSLAEGHQVNVSLFGSLVKPLQKSGQWIAALDAAADLGLFSSSREPDQRITATYTSLVDCLYSSDPYHNFTLHDVINDITYRMHPRDDSFGPPPRSDKTFRLLSTSEVHRKYRPLLNSLSNICAKVMSLNDLHGRPVSELADEAFKRGDVLLVFDTNFLIHCASKNLALSHFYVHIRKQYPHLEGKSLRRVIIPFTTVREAHQLVWNSAAPLKRAMRTLLWSRVTAILRDPSVEVLALSSEFPCISLSVISCMAYSRLNEMASENDPDLRILNTCVALQYAFRQRSAALLQGIEQISDGTMLFAFIKYHVRRHHRDVRGIACDQLLLCTMDKRLSLAADELGIQTFPRFQGLEEAAVKSEEN
Protein: S-adenosylmethionine decarboxylase proenzyme 2 (AdoMetDC 2) (SAMDC 2) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase 2 alpha chain; S-adenosylmethionine decarboxylase 2 beta chain] (D3Z6H8)
Organism: Mus musculus (Mouse)
Function: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
Interaction partners:
- Spermidine synthase
- Spermine synthase
- S-adenosylmethionine synthase isoform type-2
- S-adenosylmethionine synthase isoform type-1
- DNA
- Methionine adenosyltransferase 2 subunit beta
- Ornithine decarboxylase
- Gene model 853
- DNA
- DNA
Sequence:
MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDHLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
Protein: DNA repair protein XRCC3 homolog (X-ray repair cross-complementing protein 3 homolog) (AtXRCC3) (Q9FKM5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays essential roles in DNA damage repair in both somatic and meiotic cells. It is important for postsynaptic events following pachytene in meiosis. It is also required for DNA cross-links repair and is involved in double strand breaks (DSBs) repair.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DNA repair protein RAD51 homolog 3
- DNA repair protein XRCC2 homolog
- Meiotic recombination protein DMC1 homolog
- ATP-dependent DNA helicase Q-like 4A
- Crossover junction endonuclease MUS81
- ATP-dependent DNA helicase SRS2-like protein At4g25120
- Nibrin homolog
- DNA repair protein recA homolog 1, chloroplastic
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B
Sequence:
MQNGKIKPENLLRRSPTNRKLTTGCEILDGCLRGGISCDSLTEIVAESGCGKTQLCLQLSLCTQLPISHGGLNGSSLYLHSEFPFPFRRLHQLSHTFHQSNPSIYANYNDNPCDHVFVQNVHSVDHLFDIMPRIDGFVGNSKTRFPLKLIVLDSVAALFRSEFDNTPSDLKKRSSLFFKISGKLKQLASKFDLAIVITNQVTDLVETSDGLSGLRIGNLRYLYSSGRRVVPSLGLAWANCVNSRFFISRSDGSIVKDRSEKDENCSSSVSRSAKRRLDIVFSPYLPGSSCEFMITREGICAVQA
Protein: Kappa-casein (Q705V4)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
CEKDERFFSDKIAKYIPIQYVLSRYPSYGLNYYQQKPVALINNQFLPYPYYAKPAAVRSPAQILQWQVLSNTVPAKSCQAQPTTMAHHPHPHLSFMAIPPKKNQDKTEIPTINTIASGEPTSTPTTEAVESTVATLEDSPEVIESPPEINTVQVTSTAV
Protein: Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Transaminase A) (P00508)
Organism: Gallus gallus (Chicken)
Function: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:8665890}.
Interaction partners:
- Malate dehydrogenase
- Glutamate dehydrogenase 1, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- alanine transaminase
- Fumarate hydratase, mitochondrial
- Aspartate aminotransferase, cytoplasmic
- L-lactate dehydrogenase B chain
- Malate dehydrogenase, cytoplasmic
- Tyrosine aminotransferase
- Asparagine synthetase
Sequence:
MALLQSRLLLSAPRRAAATARASSWWSHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKSYVLNCVRKAEAMIAAKKMDKEYLPIAGLADFTRASAELALGENSEAFKSGRYVTVQGISGTGSLRVGANFLQRFFKFSRDVYLPKPSWGNHTPIFRDAGLQLQAYRYYDPKTCSLDFTGAMEDISKIPEKSIILLHACAHNPTGVDPRQEQWKELASVVKKRNLLAYFDMAYQGFASGDINRDAWALRHFIEQGIDVVLSQSYAKNMGLYGERAGAFTVICRDAEEAKRVESQLKILIRPMYSNPPMNGARIASLILNTPELRKEWLVEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSIYMTKDGRISVAGVASSNVGYLAHAIHQVTK
Protein: SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine) (P09486)
Organism: Homo sapiens (Human)
Function: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:2306517, ECO:0000269|PubMed:3400777, ECO:0000269|PubMed:7495300, ECO:0000269|PubMed:9457905}. Note=In or around the basement membrane.
Interaction partners:
- Osteocalcin
- Albumin
- Osteopontin
- Fibronectin
- Collagen alpha-1
- Vascular cell adhesion protein 1
- Collagen alpha-2
- Lumican
- Integrin-binding sialoprotein
- Vitronectin
Sequence:
MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKDLVI
Protein: Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (Deubiquitinating enzyme 2) (AtUBP2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Q8W4N3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Is involved in resistance to the arginine analog canavanine (CAN).
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 14
- AMSH-like ubiquitin thioesterase 1
- Ubiquitin carboxyl-terminal hydrolase
- At1g80210/F18B13_28
- Mov34/MPN/PAD-1 family protein
- AMSH-like ubiquitin thioesterase 3
- OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 6
- Ubiquitin carboxyl-terminal hydrolase 7
- Josephin-like protein
Sequence:
MGKKAKKKARAPTKEIQTMEISKKVSEEPPSQAGEIAEGDVKAVKETQACVHFDKALNLEKVLDKIKSSRQIKCAECNEGVYGKRGTKAKGSKGKKDFSSSDPKSNNKAIWLCLECGCYVCGGVGLPNGPQSHVLRHSRVTRHRLVIQWENPQLRWCFPCQLLLPVEKEDNGEKKDVLSEVVKLIKGRSLNNLASSDIEDQCSGSGSITSDIKLEGAVTSDIEARDGYVVRGLVNLGNTCFFNSIMQNLLSLDRLRDHFLKENGSGVGGPLASSLRKLFTETKPEAGLKSVINPRAFFGSFCSKAPQFRGYDQHDSHELLRCLLDSLSTEESALRKKRGVSDNDEKSTTLIESVFGGETSSIVSCMECGHSSKVYEPFLDLSLPVPFKKSPPKKPQPVSRAKKAKLPPKRVPKNVSKVSKVSKVLPGMVLSELNSSGKSMAVTADSDTSCSSLAPLDNGPVLETPSVLTLDNNQASESASQSDTGFDGSWLDFIGPETSGDETNLDMQEDGIDNVITAEVNQIVPSPNIVANSSVSSGDQTLEGNTERLMQDYEEIAKAEANLDEKDVQAMQSDECPATSGISAEFSQASCIGCDPGIGESSSSVNPWDEEELPLVVADSQILYMPYKEISCNDKSVEGECEASSSFVTGDHEPQNSDFVDFGGLFDEPETTEGPVFGPPSKAEASGVGFMAFSSESDPEEIDDSDLPVSVERCLGHFTKHEILSDDNAWNCENCSKNLKLQRLREKRKSNEDESRSSNTSNGWVKENEDEGFGETEILAVKQDPNDTSCVKDHSSDGRKAARIHSADESESKGTQDEDEDSEKVITVKRDATKKVLINKAPPVLTIHLKRFSQDLRGRLSKLNGHVAFKEVIDLRQYMDSRCSGEDPPVYRLAGLVEHSGTMRGGHYVAYVRGGQRVKETDSSSTAWYNVSDAYVRQVSLEKVLHSEAYILFYERIFSQE
Protein: Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase) (P22768)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the eighth step in arginine biosynthesis. Also has a catabolic function as the first enzyme of citrulline utilization as nitrogen source via arginine and the reactions involved in the arginase pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:205532}.
Interaction partners:
- Argininosuccinate lyase
- Protein ARG5,6
- Carbamoyl phosphate synthase arginine-specific large chain
- Ornithine carbamoyltransferase
- Arginine biosynthesis bifunctional protein ArgJ, mitochondrial
- Carbamoyl phosphate synthase arginine-specific small chain
- Acetylornithine aminotransferase, mitochondrial
- Multifunctional protein URA2
- Amino-acid acetyltransferase, mitochondrial
- Asparagine synthetase 2
Sequence:
MSKGKVCLAYSGGLDTSVILAWLLDQGYEVVAFMANVGQEEDFDAAKEKALKIGACKFVCVDCREDFVKDILFPAVQVNAVYEDVYLLGTSLARPVIAKAQIDVAKQEGCFAVSHGCTGKGNDQIRFELSFYALKPDVKCITPWRMPEFFERFAGRKDLLDYAAQKGIPVAQTKAKPWSTDENQAHISYEAGILEDPDTTPPKDMWKLIVDPMDAPDQPQDLTIDFERGLPVKLTYTDNKTSKEVSVTKPLDVFLAASNLARANGVGRIDIVEDRYINLKSRGCYEQAPLTVLRKAHVDLEGLTLDKEVRQLRDSFVTPNYSRLIYNGSYFTPECEYIRSMIQPSQNSVNGTVRVRLYKGNVIILGRSTKTEKLYDPTESSMDELTGFLPTDTTGFIAIQAIRIKKYGESKKTKGEELTL
Protein: Large ribosomal subunit protein eL20y (60S ribosomal protein L18a-2) (P51418)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL1x
- Large ribosomal subunit protein uL4y
- Large ribosomal subunit protein uL22y
- Large ribosomal subunit protein eL8y
- Small ribosomal subunit protein eS7x
- Large ribosomal subunit protein uL16z
- Large ribosomal subunit protein uL4z
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL6x
Sequence:
MGAFRFHQYQVVGRALPTEKDVQPKIYRMKLWATNEVRAKSKFWYFLRKLKKVKKSNGQMLAINEIYEKNPTTIKNFGIWLRYQSRTGYHNMYKEYRDTTLNGAVEQMYTEMASRHRVRFPCIQIIKTATVPAKLCKRESTKQFHNSKIKFPLVFRKVRPPSRKLKTTYKANKPNLFM
Protein: Toll-like receptor 2 (Q6TS42)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MRLVGTMTAIILIMFILAQGLECSQTCKCDQMYFCNCSSNNLHQVPTVPSDVLGLDLSFNQIESINMTDLSSYNELIILNLHKNKLRHIHRDAFKSQHNLEVLDLSLNNLNNLSPSWFHKLKSLQQLNLVGNPYSTVGPAPIFSSLVNLRTLHLGSPSLRELHKNGLDVLTHLDEMTFFGSNLRSYENGSLKAARPIGSVSLSLQNLFESDPELVSKVLQDVSHPETLLIIKDVTMKTNTSTEPFKMVKEGGTKSLTFQNSSTTDQALTSFLEFMDGSPLSFIGLEDIQFVGIGEWQKAKYTHHDSLRTAYLRNIEIEGFFGFSSMIELGFLLKHFHNVSVINATVFVIPKETTFLLKNLEYMDLSQNLLTDLTIQPTLYTGSGAYQNLNMLNVSQNVLKSLGLMSRLVTNLKKLKYLDLSYNSFVSMPEKCSWPVTLRFLNLSSTKLSTLTPCLPSSLTVLDLSENDLKAFKQRFPHLTTLILTGNRLMKLPDGKLFPSLNTLLIQRNALRMFNQSSLRSFKTLLYLEAGANNFVCSCKFVSFFKKDVEDLITLQDGRQNYVCNTPFTLRGNAIDSVRLSVFECYMIPAVSVLCFGIITALGLVVLTCHKLHVIWYLQMTKAWIQAKRKPAVGRLPEELRYDAFVSYSQHDAEWVEEILVAELEDTQPSFSLCLHKRDFRPGRWIVDNIIDSIEKSYRTLFVLSEHFVSSEWCRYELDFSHFRIMDEHNDSAVLVLLEPIKKETIPKRFCKLRKIMNSRTYLEWPEDEDKRDEFWSNLRAALQRDEC
Protein: Multifunctional procollagen lysine hydroxylase and glycosyltransferase (Lethal protein 268) [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase (EC 1.14.11.4) (Lysyl hydroxylase) (LH); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)] (Q20679)
Organism: Caenorhabditis elegans
Function: Multifunctional enzyme that catalyzes a series of post-translational modifications on Lys residues in procollagen. Catalyzes the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in type IV collagens (By similarity). Transfers galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine (By similarity). Catalyzes the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Essential for normal biosynthesis and secretion of type IV collagens. Essential for normal stability of the basement membrane.
Subcellular location: Rough endoplasmic reticulum {ECO:0000250|UniProtKB:O60568}. Endoplasmic reticulum lumen {ECO:0000305|PubMed:11071784}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9R0E1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9R0E1}; Lumenal side {ECO:0000250|UniProtKB:Q9R0E1}. Secreted {ECO:0000250|UniProtKB:O60568}. Secreted, extracellular space {ECO:0000250|UniProtKB:Q9R0E1}. Note=The majority of the secreted protein is associated with the extracellular matrix. {ECO:0000250|UniProtKB:Q9R0E1}.
Interaction partners:
- Glycosyltransferase 25 family member
- MYND-type domain-containing protein
- Histone-lysine N-methyltransferase mes-2
- Histone-lysine N-methyltransferase set-18
- Histone-lysine N-methyltransferase set-1
- Histone-lysine N-methyltransferase set-2
- Histone-lysine N-methyltransferase met-2
- SET domain-containing protein 14
- Probable histone-lysine N-methyltransferase lin-59
- Prolyl 4-hydroxylase subunit alpha-2
Sequence:
MRVLPFLLPLIPVLLATTITDLPELVVVTVATENTDGLKRLLESAKAFDINIEVLGLGEKWNGGDTRIEQGGGQKIRILSDWIEKYKDASDTMIMFVDAYDVVFNADSTTILRKFFEHYSEKRLLFGAEPFCWPDQSLAPEYPIVEFGKRFLNSGLFMGYGPEMHKILKLKSVEDKDDDQLYYTMIYLDEKLRKELNMDLDSMSKIFQNLNGVIEDVELQFKEDGTPEAYNAAYNTKPLIVHGNGPSKSHLNYLGNYLGNRWNSQLGCRTCGLEVKESEEVPLIALNLFISKPIPFIEEVLQKIAEFDYPKEKIALYIYNNQPFSIKNIQDFLQKHGKSYYTKRVINGVTEIGDREARNEAIEWNKARNVEFAFLMDGDAYFSEPKVIKDLIQYSKTYDVGIIAPMIGQPGKLFTNFWGAIAANGYYARSEDYMAIVKGNRVGYWNVPFITSAVLFNKEKLEAMKDAYSYNKNLDPDMSMCKFARDNGHFLYIDNEKYYGFLIVSDEYAETVTEGKWHPEMWQIFENRELWEARYIHPGYHKIMEPEHVVDQACPDVYDFPLMSERFCEELIEEMEGFGRWSDGSNNDKRLAGGYENVPTRDIHMNQVGFERQWLYFMDTYVRPVQEKTFIGYYHQPVESNMMFVVRYKPEEQPSLRPHHDASTFSIDIALNKKGRDYEGGGVRYIRYNCTVPADEVGYAMMFPGRLTHLHEGLATTKGTRYIMVSFINP
Protein: Forkhead box protein L2 (F1QJW8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
- Aromatase
- Kelch-like family member 23
- Doublesex- and mab-3-related transcription factor 1
Sequence:
MASYHSLDDDAMALMVHDTNAVKKEDEPLQEPGSEKTDPAQKPPYSYVALIAMAIRESTEKRLTLSGIYQYIITKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPAAHFQAGKSLFGGDAYTGYLPAPKYLQSGFMNSSWPLPQPPPPAMSYASCQMPNGNMGAMKALSTPSYNPYSRMQAMGLPNMMNSYGGMGHHQQPQHQQQSAAPSNSAAALQFTCSRQPAELYSYWEHEAKSSALHSRIDI
Protein: ADP-ribosylation factor 3 (P61204)
Organism: Homo sapiens (Human)
Function: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:17555535}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:17555535}.
Interaction partners:
- Arfaptin-1
- Neutrophil cytosol factor 2
- ADP-ribosylation factor-binding protein GGA1
- Phosphatidylinositol 4-kinase beta
- ADP-ribosylation factor 1
- Coatomer subunit beta
- Kinesin-like protein KIF23
- ADP-ribosylation factor-binding protein GGA3
- ADP-ribosylation factor 4
- Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
Sequence:
MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK
Protein: Major glycerophosphoinositol permease GIT3 (GroPCho permease GIT3) (Glycerophosphodiester transporter GIT3) (Q5A1L6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Glycerophosphodiester transporter that mediates uptake of glycerophosphocholine (GroPCho) with GIT4. GIT3 acts as the major GroPCho permease. Does not possess detectable glycerophosphoinositol (GroPIns) transport activity. The expanded ability to utilize GroPIns and GroPCho results from the organism's pathogenic nature and its need to occupy a variety of environments within its host organism. This possibility is buttressed by the fact that GroPIns and GroPCho are present and abundant in human fluids.
Subcellular location: Cell membrane {ECO:0000305|PubMed:24114876}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glycerophosphocholine phosphodiesterase GDE1
Sequence:
MSTRDLPHSFSELSYGWVKRIRAEFTVGKSKEQLLAEDYHSTTDEDSEVVTSVKANSLWPAFASGAGLFSDGYVNNSISTVLFCLKKIYPDEITKSNAINNIASIAFVGTVVGQLGFGYISDRIARKGGMMAANVMLIFFTLMCAVGSWGVTVQGFFACLTVWRFFLGVAIGAEYPTSSVIASEFANQLPPGKRNRYFSWFTNAMIDSGFVVSAFVPFVLIWIFTEKHLRALWRVAIGLGVIPPLSLFFMRLKMKNSSSFQKLHMKNVKYRDYPWWLIVKFYWFRLTIVSLIWFIYDFSAYSFGNFNTIIIGEIIPEAPIWKQWGWSIVFNLFYIPGAFLGAISADYIGPRLTLALGVGIQGVIGIAMSACLNSLKKHIAGFVVVFGIFTTFGEFGPGDNIGLLASKTSATAIRGQYYGIAAAIGKIGAFVGTWVFPAIQSKYANNANPDLQLQVPFYISSALCLFSACLAIFFCPQVGQDAIYKEDHDFVQYLSNNGFDINMLGEGGDVREVCRESDSLEKGKRDDFQVDNNSL
Protein: USH1 protein network component harmonin (A0A8I6A2P6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection {ECO:0000256|ARBA:ARBA00004316}.
Interaction partners:
Sequence:
GDRGVVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPNRLPLFDAIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPEEPLKWQYVDQFVSESGGVRGGLSSPGNRTTKEKKVFISLVGSRGLGCSISSGPIQKPGIFVSNVKPGSLSAEVGLETGDQIVEVNGIDFTNLDHKEAVNVLKSSRSLTISIVAGAGRELFMTDRERLEEARQHELQRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEQISEEEEKFKKQWEEDWGSKEQLILPKTITAEVHPVPLRKPKYDQGVEPADHLDGSTKKQRQQDFRKYEEGFDPYSMVRGDSPAWDLLSSAQEGSLDLALEGGVDSPVGKVVVSAVYEGGAAERHGGVVKGDEIMAINGKIVTDYTLAEAEAALQKAWNQGGDWIDLVVAVCPPKEYDDEL