wanglab/gogpt-training-data huggingface dataset:
Protein: Unconventional myosin-Id (Q5SYD0)
Organism: Mus musculus (Mouse)
Function: Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q63357}. Perikaryon {ECO:0000250|UniProtKB:Q63357}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q63357}. Early endosome {ECO:0000250|UniProtKB:F1PRN2}. Cytoplasm, cell cortex {ECO:0000269|PubMed:20089841}. Basolateral cell membrane {ECO:0000269|PubMed:20089841}. Note=Colocalizes with the actin cytoskeleton in the cell cortex close to the basolateral cell membrane (PubMed:20089841). Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane (PubMed:20089841). Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles (By similarity). {ECO:0000250|UniProtKB:Q63357, ECO:0000269|PubMed:20089841}.
Interaction partners:
Sequence:
MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTVEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSAIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKSKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN
Protein: Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin specific peptidase 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12) (Q9D9M2)
Organism: Mus musculus (Mouse)
Function: Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O75317}. Cytoplasm {ECO:0000250|UniProtKB:O75317}. Cell membrane {ECO:0000250|UniProtKB:O75317}. Note=Translocates from the nucleus to the cytosol on TCR stimulation, while it translocates into the nucleus in IFN signaling. USP12/WDR20/WDR48 complex is localized mainly to the plasma membrane. {ECO:0000250|UniProtKB:O75317}.
Interaction partners:
- WD repeat-containing protein 48
- WD repeat-containing protein 20
- WD repeat-containing protein 20
- PH domain leucine-rich repeat-containing protein phosphatase 1
- PH domain leucine-rich repeat-containing protein phosphatase 2
- Dystrophia myotonica WD repeat-containing protein
- Ubiquitin-ribosomal protein eS31 fusion protein
- Zinc finger-containing ubiquitin peptidase 1
- Androgen receptor
Sequence:
MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKENLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLRNGDVDNEDNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPLILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD
Protein: Nuclear receptor binding SET domain protein 2 (D6RIS1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISSPSDKK
Protein: Disintegrin and metalloproteinase domain-containing protein 28 (ADAM 28) (EC 3.4.24.-) (Thymic epithelial cell-ADAM) (TECADAM) (Q9JLN6)
Organism: Mus musculus (Mouse)
Function: May play a role in organogenesis and organ-specific functions such as thymic T-cell development.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Disintegrin and metalloproteinase domain-containing protein 22
Sequence:
MQQWSLLVVSFLLSPVPVSAIKELPKAKKYEVVYPIRLHPLRKRETQEPEPKETFETELRYKMTVNGKVAVLYLKKNNKLLAPDYSETYYNSSGNKVTTSPQIMDSCYYQGHIVNEKVSAASISTCQGLRGYISQGDEKYFIEPLSSENLDEQAHALFKDDSNEDQEKSNCGVDDALWLQGLHQDVALPATRLIKLNDGMVQEPKKYIEYYVVLDNGEFKKYNKNLAEIRKIVLEMANYINMLYNKLDAHVALVGVEIWTDGDKIKITPDANTTLENFSKWRGNDLLKRKHHDIAQLISSTDFSGSTVGLAFMSSMCSPYHSVGIVQDHSNYHLRVAGTMAHEMGHNLGMIHDYLSCKCPSEVCVMEQSLRFHMPTDFSSCSRVNYKQFLEEKLSHCLFNSPLPSDIISTPVCGNQLLEMNEDCDCGTPKECTNKCCDARTCKIKAGFQCALGECCEKCQLKKPGVVCRAAKDECDLPEVCDGKSSHCPGDRFRVNGSPCQNGHGYCLKGKCPTLQQQCMDMWGPGTKVANTSCYKQNEGGTKYGYCHVENGTHMPCKAKDAMCGKLFCEGGSGDLPWKGLTISFLTCKLFDPEDTSQGVDMVANGTKCGTNKVCINAECVDMEKTYKSANCSSKCKGHAVCDHELQCQCKEGWAPPDCENSATVFHFSIVVGVLFPLAVIFVVVAIVIQRQSARRKQRRVQRLPSTKDAKLHNQKCRPQKVKDVQPQEMSQMKKLHVSDLPSEEPEPPPDVLITKPNFPPPPIPVSLTGRAKVPFVKTPHPFSQQIGRVYLK
Protein: ESAT-6-like protein (A0A0H3LG06)
Organism: Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Protein: Reverse transcriptase domain-containing protein (H2KZ78)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MNTSEYQNPPSKYSTSTQTPQLPKVARIVPKYSVVCENSLEVVLFGTDNGVFGKYIFKNNEFLKAPDCVCQSCLRADDINLFTDSVEVQGLRATDKLHRGIDGQRLMCIGISWIGCKQSGVMDTFVNIHGIIGKYRKTPEGLILKDENKAIALLPNFPIQNTQAIMEKDLLLLNTKICPHVSQKIYFCKTTKSESVHQVVLNKLTLHFEIIKCSVCTYDKNLELEYYDKKTKLYAETVRCETTEKFAIVRSAKNENIFLSTYCPKTLDLKLQSPVAMEERKLTNSESNNWYNTSKSCEENILEKMCPANENHQTLVATEGATFGTIYWMMNENYKIDPFKIAPTIPGTGTFLTILSSLDVFKSRKVIASKFTLFENVTPKDLIDHRCEDCENNVRPTDAWLESDKGKPTLRNQMHPDYHPTYKKNSEYEDAQEDFDDIELKVFQKLCNMEDNLFKQIIDFEKPKEQFTAPPHPQMTHRVAQPHYVPVEYFNHTISDLLRQISGLQHEQAMQNGQMQHMANEIRSIGNAVCSLHSSQLQQPPNSAASMFPYPIHPMPSTFPQQAPHAPNAPQMTANSMQSIAELILAQRGIAPRRERRLTEGPKKYNRVIPPSPRIPSSTDKKEMLKKSNDRFDKLREEVSDVRTQLSGLEDTTFKKPKKLHFLEPDEESESDENGNDVDEFSEADDDDEDVDREMKVLVESLKNRVQ
Protein: T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) (O43435)
Organism: Homo sapiens (Human)
Function: Probable transcriptional regulator involved in developmental processes (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence. Is required for normal development of the pharyngeal arch arteries (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
- G protein subunit beta 1 like.
- Crk-like protein
- Transmembrane protein 26
- Homeobox protein Nkx-2.5
- Septin-5
- Homeobox protein goosecoid-2
- Proline dehydrogenase 1, mitochondrial
- Insulin gene enhancer protein ISL-1
- Protein DGCR6L
- Protein DGCR6
Sequence:
MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGGHVLKDKEVKAETSRNTPEREVELLRDAGGCVNLGLPCPAECQPFNTQGLVAGRTAGDRLC
Protein: B29/Ig-beta/CD79b (O70153)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Cd79a molecule-like.
- CD79a molecule
- Tyrosine-protein kinase Lyn
- Immunoglobulin lambda-like polypeptide 1
- CD19 molecule
- B-cell receptor CD22
- B-cell linker protein
- Membrane spanning 4-domains A1
- Joining chain of multimeric IgA and IgM
- Ig gamma-1 chain C region
Sequence:
MATLVLSPVPCHWLMFLLLLLSGEPVPAMTKSDQPPIFQGSPCSKIWQHPRFAAKKRSSMVKFHCHTDYSGVMTWFRQKGNQRPQELFPEDGHISQTRNGSVYTLTLQNIQYEDNGIYFCQQKCNSTEPDVTDGCGTELLVLGFSTLDQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE
Protein: CdaA regulatory protein CdaR (YbbR-like domain-containing protein YbbR) (c-di-AMP synthase A regulator) (O34659)
Organism: Bacillus subtilis (strain 168)
Function: Upon coexpression in E.coli stimulates the diadenylate cyclase activity of CdaA about 20-fold. In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.
Subcellular location: Cell membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cyclic di-AMP synthase CdaA
- Phosphoglucosamine mutase
- Cyclic-di-AMP phosphodiesterase GdpP
- Cyclic di-AMP synthase CdaS
- Cyclic-di-AMP phosphodiesterase PgpH
Sequence:
MDKFLNNRWAVKIIALLFALLLYVAVNSNQAPTPKKPGESFFPTSTTDEATLTDIPVKAYYDDENYVVTGVPQTVNVTIKGSTSAVKKARQTKNFEIYADMEHLKTGTHKVELKAKNVSDGLTISINPSVTTVTIQERTTKSFPVEVEYYNKSKMKKGYSPEQPIVSPKNVQITGSKNVIDNISLVKASVNLENADETIEKEAKVTVYDKDGNALPVDVEPSVIKITVPVTSPSKKVPFKIERTGSLPDGVSIANIESSPSEVTVYGSQDVLDSLEFIDGVSLDLSKINKDSDIEADIPLPDGVKKISPSKVTLHIEVDSEADQKFENVPIKTVGLSSSQNIEFLDPESQAIDVTAKGSPTNINKLKKSDIELYVNVSDLEDGEHSVKLEVNGPQNVTWSLGRKNAKIKLTSKKSNTSTNDNSSNTSGNQDTDKQTNDQKNNQQEDTKNTDKNNNDQNQDGNKDQNQDQDEDESTANSQSSSE
Protein: Alkaline ceramidase (AlkCDase) (Alkaline CDase) (AtACER) (EC 3.5.1.-) (Acyl-CoA independent ceramide synthase 1) (AtCES1) (Alkaline ceramidase YPC1) (AtYPC1) (Alkaline dihydroceramidase ACER) (Alkaline phytoceramidase) (aPHC) (Q94IB9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). Affects plant morphogenesis. Required for the formation of wax layer that ensure cuticle permeability. Implicated in abscisic acid (ABA)-mediated stomatal closure. Involved in both biotic and abiotic stresses. Promotes salt resistance and defenses responses toward pathogenic bacteria (e.g. P.syringae) and against the fungal toxin fumonisin B1 (FB1).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18643979, ECO:0000269|PubMed:25619405}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:25619405}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Neutral ceramidase 1
- Sphingosine kinase 2
- Sphingosine kinase 1
- 3-dehydrosphinganine reductase TSC10B
- Neutral ceramidase 3
- 3-dehydrosphinganine reductase TSC10A
- Neutral ceramidase 2
- Sphinganine C4-monooxygenase 2
- Sphinganine C4-monooxygenase 1
- Long chain base biosynthesis protein 1
Sequence:
MADGISSFWGPVTSTIECCEMNYAYSSYIAEFYNTISNVPGILLALIGLVNALRQRFEKRFSILHISNMILAIGSMLYHATLQHVQQQSDETPMVWEILLYMYILYSPDWHYRSTMPTFLFLYGAAFAIVHAYLRFGIGFKVHYVILCLLCIPRMYKYYIHTEDTAAKRIAKWYVATILVGSICWFCDRVFCKTISQWPVNPQGHALWHVFMSFNSYCANTFLMFCRAQQRGWNPKVKYFLGVLPYVKIEKPKTQ
Protein: Transducin-like enhancer protein 3 (rTLE3) (Q9JIT3)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q04726}.
Interaction partners:
- Hepatocyte nuclear factor 3-alpha
- TLE family member 1, transcriptional corepressor
- Histone deacetylase 1
- NK2 homeobox 2
- Nuclear receptor interacting protein 1
- Lymphoid enhancer-binding factor 1
- GATA-binding protein 3.
- Transcription factor 7 like 2
- Transcription factor 7 like 2
- Catenin beta-1
Sequence:
MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSTNNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPSQMSAAAAAAAAAYGRSPMVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY
Protein: DEAD-box ATP-dependent RNA helicase 38 (EC 3.6.4.13) (Low expression of osmotically-responsive genes 4 protein) (Protein CRYOPHYTE) (Q93ZG7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: ATP-dependent RNA helicase essential for mRNA export from the nucleus. Plays an important role in the positive regulation of CBF/DREB transcription factors.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12165572}. Nucleus {ECO:0000269|PubMed:12165572}.
Interaction partners:
- mRNA export factor GLE1
- Nucleoporin GLE1-like protein
- Nuclear pore complex protein NUP214
- Protein RAE1
- At4g27240
- AT5g54630/MRB17_13
- C2H2-like zinc finger protein
- Nuclear pore complex protein NUP96
- Nuclear pore complex protein NUP160
- Regulator of nonsense transcripts 1 homolog
Sequence:
MADTVEKVPTVVESSSSSTVEASNSAEKTEPTTEKKKWGDVEDDDDEEEAVSELNSLSIKEEEKPDSILEEPEDSNIKAVTSGDTPYTSASRFEDLNLSPELMKGLYVEMKFEKPSKIQAISLPMIMTPPHKHLIAQAHNGSGKTTCFVLGMLSRVDPTLREPQALCICPTRELANQNMEVLQKMGKFTGITAELAVPDSTRGAPAATRGAPVSAHVVIGTPGTLKKWMAFKRLGLNHLKILVFDEADHMLATDGFRDDSLKIMKDIGRVNPNFQVLLFSATFNETVKDFVARTVKDPNQLFVKREDLALDSVKQYKVVCPKEQNKIEVIKDQIMELGDIGQTIIFVKTKASAQKVHKALAEMGYDVTSVHGNLTESDRDKIVKEFKECLTQVLIATDVIARGFDQQRVNLVVNYNLPTKYETGEPDYEVYLHRVGRAGRFGRKGAVFNLLLDDGWDKEVMEKIEKYFEANVKEIKSWNSEEEYKSALKEAGLLDE
Protein: Protein DJ-1 homolog D (AtDJ1D) (Lactoylglutathione lyase DJ1D) (EC 4.4.1.5) (Q9M8R4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. May be involved in oxidative stress response.
Interaction partners:
- Hydroxyacylglutathione hydrolase 2, mitochondrial
- Probable hydroxyacylglutathione hydrolase 2, chloroplastic
- Lactoylglutathione lyase
- Hydroxyacylglutathione hydrolase cytoplasmic
- Lactoylglutathione lyase GLX1
- Probable lactoylglutathione lyase, chloroplastic
- Hydroxyacylglutathione hydrolase 1, mitochondrial
- Protein DJ-1 homolog C
- DJ-1 protein homolog F
- DJ-1 protein homolog E
Sequence:
MANSRTVLILCGDYMEDYEVMVPFQALQAFGITVHTVCPGKKAGDSCPTAVHDFCGHQTYFESRGHNFTLNATFDEVDLSKYDGLVIPGGRAPEYLALTASVVELVKEFSRSGKPIASICHGQLILAAADTVNGRKCTAYATVGPSLVAAGAKWVEPITPDVCVVDGSLITAATYEGHPEFIQLFVKALGGKITGANKRILFLCGDYMEDYEVKVPFQSLQALGCQVDAVCPEKKAGDRCPTAIHDFEGDQTYSEKPGHTFALTTNFDDLVSSSYDALVIPGGRAPEYLALNEHVLNIVKEFMNSEKPVASICHGQQILAAAGVLKGRKCTAYPAVKLNVVLGGGTWLEPDPIDRCFTDGNLVTGAAWPGHPEFVSQLMALLGIQVSF
Protein: Carnitine O-acetyltransferase (Q59MQ8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Carnitine O-acetyltransferase
- Carnitine O-acetyltransferase, mitochondrial
- Peroxisomal hydratase-dehydrogenase-epimerase
- Isocitrate lyase
- Malate synthase
- Mitochondrial thiamine pyrophosphate carrier 1
Sequence:
MTQEQFYTFENEASLPKLPVPSLVSTTQQLLASLKPLLPQNEYATVVDEATEFVGNDIINLIQKHLVAISENENYTNYLNFVNDDKTPSIYGEIRGDILPRNPYLVLEEDPYSKTINPPNQAQRAANLVNSSLKFAITLRNETLKPDVTPKNGNALTMKCYMDLFGTTREPEQDDRGFDIRIKKYQHINDSRHILIISNNQFYTLEVLTEFDENEYQQTNSKHNIWFNDSELSKILQHIIDESNKVDAVNAIRNSVGSITTQTLKYWKFARLELEQSNTENLKLIDDALFVLILDSNTPVTDGEKTQVISHGTSVLSSDNVQIGTCTSRWYDKLQIVVTKNSVAGIVWESMTMDSTAILRFISDIYTDSVLKMAKNINGSEYTLFDPNITFASIGKDGNGVVKPEPKLLEFNKTKALQHVIHLSETRLADLLDQHEYMTHTIKLDSYLTTKFNLSVDSIMQVCFQIAYYSLYGRIVNTLEPITTRKFRDARTELVAVQNQSLANLVKLYITNASPSEKFEAFKKCCALHKTQYHDAMSGKGFERHLMTIVQVVKKPKVIARLNQVNTHLPPIPEDLCQAGINLPLLLNPSIDKLSSPELLVSNCGNPALRLFGITPAIDQGFGIGYIIHRDKVLITVCSKHRQTARYLDTFHRVVHDIKIRLRASSNFLLSISDSERRKNELQRLRIEHELSNVSLDIPTMKHPIPLTIGKSEISIDNIALKTARTGRATRSEEKSLGNNATDDSNVGVGGDEDEDEDDSKFELMGGYGYFDFGELELRSDEVSRNESYLNSQVQSNLSSAMSSRRHSFTNLQKIASRSHDSHLPQQLQQQQQQQKYDIKEKQSLSERIRDKLSHSQDTLSSVQSVLEEDVQKNEPTKKSSIGRSLDMSKLS
Protein: Serine protease 55 (EC 3.4.21.-) (Testis serine protease 1) (T-SP1) (Q6UWB4)
Organism: Homo sapiens (Human)
Function: Probable serine protease, which plays a crucial role in the fertility of male mice including sperm migration and sperm-egg interaction.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:18844450}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q14BX2}. Cytoplasm, cytosol {ECO:0000269|PubMed:18844450}. Note=Mainly found in the membrane part of the cells and only in small amounts in the cytosol. {ECO:0000269|PubMed:18844450}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol {ECO:0000269|PubMed:18844450}. Note=Present primarily in the cytosol and only in minor amounts in the membrane fraction. {ECO:0000269|PubMed:18844450}.
Interaction partners:
Sequence:
MLLFSVLLLLSLVTGTQLGPRTPLPEAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGSPRSWLLLCPLSHVLFRAILY
Protein: Vomeronasal type-1 receptor 43 (Vomeronasal type-1 receptor A2) (Vomeronasal type-1 receptor A5) (Q8VIC9)
Organism: Mus musculus (Mouse)
Function: Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Vomeronasal type-1 receptor 44
Sequence:
MSKILFFSPCSLFSHTMNKNSRLHTNSNIGNTFFSEIGIGITGNSFLLLYHILKFIRGHRPRLTDLPIGLLSLIHLLMLLVAAFIATDIFISRRGWDDIICKFLVYLYRVLRGLSLCTTSMLSVLQAIILSPRSSCLSKFKHISLHHILCAILFLSVLYMLISSQLLVSIIATPNLTTNDLTYVTQSCSILPLSYLVESINSTLLAIREYFLISLMFLSTWYIVALLCMHRKQTQHLQETRLSLKKSPEQSATQTILMLMTFFVLMTIYDNIVSCLRTMLLNDPTSYSIELFMIHIYATVSPFVFMSNEKHIVNFLRSMGKRMINLNLH
Protein: BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)] (Q9JLT6)
Organism: Rattus norvegicus (Rat)
Function: Induces caspases and apoptosis. Counters the protective effect of BCL2.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P70444}. Mitochondrion membrane {ECO:0000250|UniProtKB:P70444}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:P55957}. Note=When uncleaved, it is predominantly cytoplasmic (By similarity). {ECO:0000250|UniProtKB:P70444}.; SUBCELLULAR LOCATION: [BH3-interacting domain death agonist p15]: Mitochondrion membrane {ECO:0000250|UniProtKB:P70444}. Note=Translocates to mitochondria as an integral membrane protein. {ECO:0000250|UniProtKB:P70444}.; SUBCELLULAR LOCATION: [BH3-interacting domain death agonist p13]: Mitochondrion membrane {ECO:0000250|UniProtKB:P70444}. Note=Associated with the mitochondrial membrane. {ECO:0000250|UniProtKB:P70444}.
Interaction partners:
- Apoptosis regulator BAX
- BCL2-antagonist/killer 1, isoform CRA_b.
- Bcl-2-like protein 1
- Apoptosis regulator Bcl-2
- Caspase-8
- Bcl-2-related protein A1
- Bcl-2-like protein 11
- Phorbol-12-myristate-13-acetate-induced protein 1
- Caspase-2
- Caspase-1
Sequence:
MDSEVSNGSGLGAEHITNLLVFGFLRNNDRDFHQELEVLGQELPVQVYLEGDREDELQTDGSRASRSFYHGRIEPDSESQDEVIHNIARHLAQAGDELDHSIQPTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVKTSFPRDMENDKAMLIMTMLLAKKVASHAPSLLRDVFRTTVNFINQNLFSYVRDLVRNEMD
Protein: Four and a half LIM domains 1 (Q5JXH7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVED
Protein: Meis1 protein (B1WC31)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
- BTB/POZ domain-containing protein 9
- PBX homeobox 1.
Sequence:
MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDVTRAANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
Protein: Candida glabrata strain CBS138 chromosome B complete sequence (Q6FXG1)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Candida glabrata strain CBS138 chromosome M complete sequence
- Calmodulin
- Candida glabrata strain CBS138 chromosome G complete sequence
- Calcineurin subunit B
- Candida glabrata strain CBS138 chromosome M complete sequence
- Candida glabrata strain CBS138 chromosome F complete sequence
- Candida glabrata strain CBS138 chromosome M complete sequence
- Candida glabrata strain CBS138 chromosome F complete sequence
- Candida glabrata strain CBS138 chromosome K complete sequence
- Candida glabrata strain CBS138 chromosome L complete sequence
Sequence:
MPMVKRQLTERYEPGNEAQDADDGFVPPFVNIVPPDSDEDKNSSSNSLPIRRIRKRGPYEDSDEGDYSDNDDDFEERVEYSPRRLEGTFGDDGELDGISEHDHSHRDDMISNTDTAHSDRVSSLGMSSKAESPSKKWEPRIANLFKSALGNNNAKQKPQLSLRTTSLSTNTQDKARKYSSSDEPGSPSAKSAVSFHSSGVRSNVLHRSNKSGESSPRRRSISTDGPPRSAKVLSIIDADDMDEFEDMKRGFQSAIEDKKFAWLPQLQQETESADELEAGDKSKLNIDIKSTLTPRGRSGSQFRNDSTEDLHFEPGLFSSPSKHSSRRPSIIASSIAHGLGINLEKDKNVDTVSIEVELPDFDEYENAKKRPPLILHGNSLGYFGPNNPLRYKVAHILLNKYYKIAHILLLTFLTALLAYRSYEPENFDFLYRFRNWSDYIIFILFILFTSNDIAKIFAFGFWDDSQMFAYHQLEYISLLERFGITKLYHLIKKKYGPKIVHFLLPFNVISDESEKETIQRNMKANISAKNDTNSKSLKFNCPRAFCRSSWNRIDLLSSVCFWLGMFLSINNYDKRVGIRIFKPLAAMRILRLVNTDTGITSILRGLKYGMPQLINVGSMLVYFWVFFGILGVQIFKGSFRRQCVWYNPENPNDRYQYQLQFCGGYLEPVTKKKMNYIFEDGREGPVSKGFMCPQYSKCVSSSNPFNGRVSFDNIINSMELVFIVMSANTFSDIMYYTMNSDEFSACLFFIISIFVLTIWMMNLLIAALVSSFQLAHEEFKKKKLEESSNESWPIRFALGYWRYFKVKASQTEFPSWAERGLKYYEKIEPVFIILIMFDLIMRCLIKDTSSQHFVTTLLRIDRGVTIVLFIESIFRLVLHIPNMWKFLTRFNYVYDLFVAILTLVITILANAGLLGHGYYWLSFFQITRFYRLVIYIGFTRKLWKEVLGNGIMIWNLTAFYFFFTFLASIILSLYFEGVIPQDQIEDQLLGMYSLPNSFLSLYSIGSTENWTSILYIIQQYSPNISSAFFSTVFLIIWFILSNSVILNIFIALISESLEVKEDDKRPMQIKHYLKHIYPQKIQRFRHASLLARIKKKIFRTDSQEDSRDFKQFLMRGTAIMNIAQNLGDLSKEFNTEQDRDIVTLLVRLTEYIPILRKFGIYSNNPFYKRNEIMFSETSDLNGRNYMLQLNEFEDEKLDYLQKHSMFNYSYYLFSPRHRFRKFCQKLVPPSYGKRTDNYKFYEDDTDTYSRKTYFNHIWRDLFVVFYAAATVLLIVFSCYVTPIYRMKRNMSSKNWVTYVDAAFLAIFCVEFIIKTVADGFIYTPNAYARNPWNLIDFFVLISMWINLIAFLRNDGNLSRVFKGLTALRALRCLTISNTARETFKVVLFNGIGKILEAGLLSLTLLFPFTVWGLNLFRGRLGVCNDGDLGRDECFNEFSNEVFQWNVMMPRVYDNPELYLDSFTSAFNSLFQIISLEGWTDLLGNLMNSTGVGKPASLLASTGNAVFIIAFNFLSIVFILNLFVSFIVNNQAKSTGSAYFTSEEKAWLESQKLLSQAKPIAIPTFHDISRVRIFLYNIAVEKNNIYYAIFLQTVTYIHIIMLLSLTYKDHGSGLLYSQVYFMFSTTVFLLQELFHVYGAGLRIYKMNKWNLIRIQILIVSFLLTLISFNVDRAYIWYHNVNGFFHLVIFLFIIPQNDTLSELIETAMASLPPILSLTYTWFILFLVYAIALNQIFGLTRLGPNTTDNINFRTVLKALIVLFRCSFGEGWNYIMDDLKVKEPYCSQRVKGNYSDCGSQTYAYILLISWNILSMYIFLNMFISLIIGNFSYVYRKGGTKSEVNRGEIRKYVETWARFDPDGTGKLDFEYLPKIMHSFNGPLSFKIWEGKLTVKNLVKNYMEVNPNDPYDVKVDLEGLNKELDSINMESIMNRRLQYRRFVQEVYYTQAYMGYMKFSTLLDLVPLYTTYDPRECLGIDQYVRHLYIMGKVDRYLDNERNVDVLDMVVTRWKHHLKRKYGPNYKLDQDSIKKDLNIKVPEIKTWNESVESVTTPRVSYGVNDFIWSPRNNSNSSAYSKPLPQSHARPIPPHIQISNSRVMEYTNRDSLSSLENIHNQSDEELKDPFRDI