wanglab/gogpt-training-data huggingface dataset:
Protein: Probable serine/threonine-protein kinase WNK4 (AtWNK4) (EC 2.7.11.1) (Protein kinase with no lysine 4) (Q9LVL5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May regulate flowering time by modulating the photoperiod pathway.
Interaction partners:
- Inactive serine/threonine-protein kinase BKN2
Sequence:
MNMNQVAEYVETDPTGRYGRFAEILGRGAMKTVYKAIDEKLGIEVAWSQVKLKEVLRSSVDLQRLYSEVHLLSTLNHKSIIRFYTSWIDVHNHTLNFITELFTSGTLRQYKNKYLRIDIRAIKSWARQILEGLVYLHEHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLARMLRDCHSAHSIIGTPEFMAPELYEENYNELIDVYSFGMCFLEMITSEFPYSECNHPAQIYKKVVGGKLPGAFYRVGDIEAQRFIGKCLVSASKRVSAKELLQDPFLASDESWMVYTSGAGNPKPFLNENEMDTLKLEDDELRTEMSIAGKLGAEDNKIDLEVQIAYDNGLANNVFFPFDIMNDTSIDVAKEMVKELEIIDWEPVEIAKMIDGAISSLVSDWKYEEDDETPHDHHRHRTDSFHSSSSHASSSQASLSNYMARGLQDWVQDDLHDETYSQSSSHSGSYSNLNYIAVDEYSSQSPVMSRTHNMTRFCPEESSHLQSGQANAYAASSSTNRSLASDNRTLTRNRSLVDVQRQLLHRSPGEEARKRRLFKTVGDVETVGFQSPYAVSRKPPSSRR
Protein: Probable transcriptional regulatory protein (Possibly TetR-family) (P96821)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable carbon monoxyde dehydrogenase
- Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0146
- Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0145
Sequence:
MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSVASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQVFSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFYIGFVGSYQRMATITDSFQQLLAGTLWRPPT
Protein: S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (SAND) (EC 4.2.-.-) (Bone-expressed sequence tag 5 protein) (Radical S-adenosyl methionine domain-containing protein 2) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) (Viperin) (O70600)
Organism: Rattus norvegicus (Rat)
Function: Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) via a SAM-dependent radical mechanism. In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication. Therefore, inhibits a wide range of DNA and RNA viruses. Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8WXG1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8WXG1}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8WXG1}. Golgi apparatus {ECO:0000250|UniProtKB:Q8WXG1}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8WXG1}. Lipid droplet {ECO:0000250|UniProtKB:Q8WXG1}. Mitochondrion {ECO:0000250|UniProtKB:Q8WXG1}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q8WXG1}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8WXG1}.
Interaction partners:
- Interferon-induced protein 44
- Ubiquitin-like protein ISG15
- UMP-CMP kinase 2, mitochondrial
- Ubl carboxyl-terminal hydrolase 18
- Interferon-induced protein with tetratricopeptide repeats 1
- Interferon-induced GTP-binding protein Mx1
- Interferon-induced GTP-binding protein Mx3
- Interferon-induced, double-stranded RNA-activated protein kinase
- Interferon-induced protein with tetratricopeptide repeats 3
- Interferon-induced helicase C domain-containing protein 1
Sequence:
MLVPTALAARLLSLFQQQLGSLWSGLAMLFCWLRIALGWPDPGKGQPRVRGEPKETQETHEDPGSAQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGMEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGDYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRKWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFEAFLQRHKDVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSRSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW
Protein: ATP synthase F(0) complex subunit C3, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase membrane subunit c locus 3) (ATP synthase proteolipid P3) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C3) (ATPase protein 9) (ATPase subunit c) (P48201)
Organism: Homo sapiens (Human)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
Subcellular location: Mitochondrion membrane; Multi-pass membrane protein.
Interaction partners:
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit b, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit d, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit F6, mitochondrial
- ATP synthase F
Sequence:
MFACAKLACTPSLIRAGSRVAYRPISASVLSRPEASRTGEGSTVFNGAQNGVSQLIQREFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
Protein: Protein SLA2 (Transmembrane protein MOP2) (P33338)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for cellular morphogenesis and polarization of the cortical cytoskeleton. It might act in concert with proteins such as CDC42 and CDC43 to limit the region of cortical patch formation to the cortex of the bud. Required for the accumulation and/or maintenance of plasma membrane H(+)-ATPase on the cell surface.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00243}. Cytoplasm, cytoskeleton, actin patch. Cytoplasm, cell cortex. Bud tip.
Interaction partners:
- Actin cytoskeleton-regulatory complex protein PAN1
- Epsin-1
- Clathrin light chain
- Actin cytoskeleton-regulatory complex protein END3
- Actin cytoskeleton-regulatory complex protein SLA1
- Proline-rich protein LAS17
- Clathrin heavy chain
- EH domain-containing and endocytosis protein 1
- Actin
- Verprolin
Sequence:
MSRIDSDLQKALKKACSVEETAPKRKHVRACIVYTWDHQSSKAVFTTLKTLPLANDEVQLFKMLIVLHKIIQEGHPSALAEAIRDRDWIRSLGRVHSGGSSYSKLIREYVRYLVLKLDFHAHHRGFNNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQDSLDEFSQIIFASIQSERRNTECKISALIPLIAESYGIYKFITSMLRAMHRQLNDAEGDAALQPLKERYELQHARLFEFYADCSSVKYLTTLVTIPKLPVDAPDVFLINDVDESKEIKFKKREPSVTPARTPARTPTPTPPVVAEPAISPRPVSQRTTSTPTGYLQTMPTGATTGMMIPTATGAANAIFPQATAQMQPDFWANQQAQFANEQNRLEQERVQQLQQQQAQQELFQQQLQKAQQDMMNMQLQQQNQHQNDLIALTNQYEKDQALLQQYDQRVQQLESEITTMDSTASKQLANKDEQLTALQDQLDVWERKYESLAKLYSQLRQEHLNLLPRFKKLQLKVNSAQESIQKKEQLEHKLKQKDLQMAELVKDRDRARLELERSINNAEADSAAATAAAETMTQDKMNPILDAILESGINTIQESVYNLDSPLSWSGPLTPPTFLLSLLESTSENATEFATSFNNLIVDGLAHGDQTEVIHCVSDFSTSMATLVTNSKAYAVTTLPQEQSDQILTLVKRCAREAQYFFEDLMSENLNQVGDEEKTDIVINANVDMQEKLQELSLAIEPLLNIQSVKSNKETNPHSELVATADKIVKSSEHLRVDVPKPLLSLALMIIDAVVALVKAAIQCQNEIATTTSIPLNQFYLKNSRWTEGLISAAKAVAGATNVLITTASKLITSEDNENTSPEQFIVASKEVAASTIQLVAASRVKTSIHSKAQDKLEHCSKDVTDACRSLGNHVMGMIEDDHSTSQQQQPLDFTSEHTLKTAEMEQQVEILKLEQSLSNARKRLGEIRRHAYYNQDDD
Protein: Large ribosomal subunit protein uL18c (50S ribosomal protein L18, chloroplastic) (CL18) (Q9SX68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein bS6c
- Large ribosomal subunit protein cL37
- Large ribosomal subunit protein bL28c
- Large ribosomal subunit protein uL24c
- Large ribosomal subunit protein bL9c
- Large ribosomal subunit protein bL35c
- Large ribosomal subunit protein uL4c
- F14B2.25/F14B2.25
- Large ribosomal subunit protein bL27c
- Large ribosomal subunit protein uL29c
Sequence:
MTSVSGCGSVSLITNRSAFLGNGLQHRAVFLKPWSSSSLQSRSMVVEAKTKTSSEDRIARHSRIRKKVNGTTERPRLCVFRSNKHLYVQVIDDTKMHTLASASTKQKPISEEFDYTSGPTIEVAKKVGEVIAKSCLEKGITKVAFDRGGYPYHGRIEALAAAAREHGLQF
Protein: Receptor tyrosine kinase-like orphan receptor 2 (Tyrosine-protein kinase transmembrane receptor ROR2) (E7FCE4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
- Protein Wnt
- Protein Wnt-5b
- Inactive tyrosine-protein kinase transmembrane receptor ROR1
- Frizzled class receptor 1
- Frizzled class receptor 2
- Protein Wnt
- Protein Wnt-11
- Frizzled-4
- Frizzled-5
- Frizzled class receptor 7a
Sequence:
MFPVRMYHILRITTGAHLVATFIFFATFAYAEADVNLFESEEIEALAEAQSGGLPTPEGYYLEFLEQPNNITIVQGQTATLHCKVAGHPRPSIRWLKNDAPVVQEQGRVSIRKTEAGSKLRIQDLDTTDTGYYQCVATNSIKVISATGVLYVRLGNTGQSPAHGAEDSTHEKGFCQPYRGIACARFIGNRSIYVESLQMQGESENRITAAFTMIGTSTQLSDQCSEFAIPSFCYYVFPLCEEGTRGPRRRQLCRDECEALENDLCNAEYTIARSNPLILMQLELPVCSLLPHPGSPDASSCIRIGLPPQYSPPDHSCYNESGGNYKGTVSVTKSGFQCQPWSAQYPHSHHLSPIEYPQLRGGHNFCRNPGGQMESPWCFTLDPNVRVDLCDIPPCNPPEKMKKELLYILIPSVATPLVFACLFFLICMCRNKQKESVDTPTRRQLTASPSQEMELPLLNQHKHQAKLRELNLSAVRFMEELGEDRFGKVYKGHLYGTAPGEQTQVVAIKTVKDKDEGPLREEFRHEAMLRSRLQHPNIVCLLGVITKEQPMSMIFSYSGQGDLHEFLVMRSPHSDVGSSDDDKTVKSTLEQADFLHIVTQVAAGMEYLSSHHVVHKDLAARNILVCDKLNVKILDLGLFREVYSADYYKLMGASPFPIRWMSPEAILYGKFSTDSDIWSYGVVLWEIFSYGLQPYCGYSNQDVIEMVRNRQVLSCPDDCPAWIYTMMLECWNEFPSRRPRFKDIHARLRTWESLSNYNSSAQTSGASNTTQTSSLSTSPVSNISNARYVSPKKSSPFPQPQFVSMKGQMRPMVPPQLYIPVNGYQPMPAYPYLQNFYPMQIPMQMPPQQMHPQMVAKAGSHHSGSGSTSTGYVTTAPSNGSGTDKVALMNEDLKATEDDFADGASQKGLHHEDLSVPETELLGDNDSPHTEDNEINSDA
Protein: Lipid-anchored plasma membrane protein CPP3 (C-terminally palmitoylated protein CPP3) (Cysteine-rich protein CPP3) (Q6Q5X2)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cell membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:38159851}; Lipid-anchor {ECO:0000269|PubMed:38159851}. Note=Localization is partially skewed towards the growing bud, and this localization pattern is dependent on endocytosis and polarized secretion. {ECO:0000269|PubMed:38159851}.
Interaction partners:
- Uncharacterized protein YMR182W-A
- Uncharacterized protein YJL136W-A
- Uncharacterized protein YJL133C-A
Sequence:
MRHHQNMHYAPQQQPVYVQQPPPRRESGGCCRTCCHFLCCLCLINLCCDVF
Protein: Probable trehalase (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase) (P35172)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Periplasmic acid trehalase ATH1
- Trehalose-phosphatase
- Cytosolic neutral trehalase
- Trehalose synthase complex regulatory subunit TPS3
- Trehalose synthase complex regulatory subunit TSL1
- Alpha,alpha-trehalose-phosphate synthase 56 kDa subunit
- Bifunctional protein GAL10
- Glycogen phosphorylase
- Glycogen [starch] synthase isoform 2
- 1,4-alpha-glucan-branching enzyme
Sequence:
MVDFLPKVTEINPPSEGNDGEDNIKPLSSGSEQRPLKEEGQQGGRRHHRRLSSMHEYFDPFSNAEVYYGPITDPRKQSKIHRLNRTRTMSVFNKVSDFKNGMKDYTLKRRGSEDDSFLSSQGNRRFYIDNVDLALDELLASEDTDKNHQITIEDTGPKVIKVGTANSNGFKHVNVRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVDRLSRLITTQFWTSLTRRVDLYNIAEIARDSKIDTPGAKNPRIYVPYNCPEQYEFYIQASQMNPSLKLEVEYLPKDITAEYVKSLNDTPGLLALAMEEHVNPSTGERSLVGYPYAVPGGRFNELYGWDSYLMALGLIESNKVDVARGMVEHFIFEIDHYSKILNANRSYYLCRSQPPFLTDMALLVFEKIGGKNNPNAIQLLKRAFRAAIKEYKEVWMSSPRLDSLTGLSCYHSDGIGIPPETEPDHFDTILLPYAEKYNVTLEKLRYLYNEGMIKEPKLDAFFLHDRAVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEKDIAFVIKEYFGNEYKDENDGTVTDSEHWEELAELRKTRINKYMWDEDSGFFFYYNTKLKCRTSYESATTFWSLWAGLATEEQAKITVEKALPQLEMLGGLVACTEKSRGPISIDRPIRQWDYPFGWAPHQILAWKGLSAYGYQQVATRLAYRWLYMITKSFVDYNGMVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNTSYLLGLKYMNNHARRALAACSPPLPFFNSLKPSEKKLYYL
Protein: NAD-dependent protein deacetylase SRT1 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (Q9FE17)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: NAD-dependent protein deacetylase (By similarity). Has deacetylase activity towards H3K9Ac (By similarity). May have a function in the safeguard against genome instabiliy and DNA damage to ensure plant cell growth (By similarity). Involved in responses to ethylene leading to the transcriptional repression of some ethylene-responsive genes via the regulation of histone acetylation H3K9Ac.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P59941}.
Interaction partners:
- NAD-dependent protein deacylase SRT2
- Glutamine-dependent NAD
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase
- NAD
- NAD kinase 2, chloroplastic
- Histone deacetylase 2
- Uridine nucleosidase 1
- Nudix hydrolase 19, chloroplastic
- Alkaline-phosphatase-like family protein
- NADH kinase
Sequence:
MSLGYAEKLSFIEDVGQVGMAEFFDPSHLLQCKIEELAKLIQKSKHLVVFTGAGISTSCGIPDFRGPKGIWTLQREGKDLPKASLPFHRAMPSMTHMALVELERAGILKFVISQNVDGLHLRSGIPREKLSELHGDSFMEMCPSCGAEYLRDFEVETIGLKETSRKCSVEKCGAKLKDTVLDWEDALPPKEIDPAEKHCKKADLVLCLGTSLQITPACNLPLKCLKGGGKIVIVNLQKTPKDKKANVVIHGLVDKVVAGVMESLNMKIPPYVRIDLFQIILTQSISGDQRFINWTLRVASVHGLTSQLPFIKSIEVSFSDNHNYKDAVLDKQPFLMKRRTARNETFDIFFKVNYSDGCDCVSTQLSLPFEFKISTEEHVEIIDKEAVLQSLREKAVEESSCGQSGVVERRVVSEPRSEAVVYATVTSLRTYHSQQSLLANGDLKWKLEGSGTSRKRSRTGKRKSKALAEETKA
Protein: Uncharacterized protein (L1J207)
Organism: Guillardia theta (strain CCMP2712) (Cryptophyte)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSSITCDPAIYGEWSRENQFCVEKSLITLDGIKYVQLVMAVVSACQVFFMVTRAPKVPWEAIYLPTTEMITYSLAFTGNGYIRVANGKYLPWARMASWLCTCPIMLGLVSNMALVKYKSIPLNPMMIAASSICTVFGITASVVLDPLHVWLYCFISSIFFIFEMVVAFAIFAITIHDFQTIGSPMSLKVVERLKLMRIVFYVSWMAYPILWSFSSTGACIMSENTSSVLYLLGDALCKNTYGILLWATTWGLLNGKWDRDYVKGRNVDGTLMPEYEQDLEKGNTERYEDARAGETFEVKMFGRTLTSVRRSRRRPRRDIVFNGGDRNRLSDSDSERRRRRKKYQRKDSESENSSDESMGSEHEKNRRKGKKKNKENRRSAPPKEDSTSDTLRDAEIKRIMDLMKRNAGSDIPGLDGDGRLRDDGGLIPTRNEEHDDSA
Protein: Zinc finger protein 408 (PR domain zinc finger protein 17) (Q9H9D4)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000269|PubMed:23716654, ECO:0000269|PubMed:25882705}.
Interaction partners:
- G patch domain-containing protein 3
- Tetraspanin-12
- E3 ubiquitin-protein ligase RNF25
- Frizzled-4
- Norrin
- Zinc finger protein 212
Sequence:
MEEAEELLLEGKKALQLAREPRLGLDLGWNPSGEGCTQGLKDVPPEPTRDILALKSLPRGLALGPSLAKEQRLGVWCVGDPLQPGLLWGPLEEESASKEKGEGVKPRQEENLSLGPWGDVCACEQSSGWTSLVQRGRLESEGNVAPVRISERLHLQVYQLVLPGSELLLWPQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSVPSAASEPTVVLLQAEPQLLDTHREEEVSPARDVVEVTISESQEKCFVVPEEPDAAPSLVLIHKDMGLGAWAEVVEVEMGT
Protein: Tetraacyldisaccharide 4'-kinase (EC 2.7.1.130) (Lipid A 4'-kinase) (P27300)
Organism: Escherichia coli (strain K12)
Function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
Interaction partners:
- 3-deoxy-D-manno-octulosonic acid transferase
- Lipid-A-disaccharide synthase
- ATP-dependent lipid A-core flippase
- Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
- UDP-3-O-
- UDP-3-O-acyl-N-acetylglucosamine deacetylase
- 3-deoxy-manno-octulosonate cytidylyltransferase
- 2-dehydro-3-deoxyphosphooctonate aldolase
- Lipid A biosynthesis lauroyltransferase
- UDP-2,3-diacylglucosamine hydrolase
Sequence:
MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTLLASGN
Protein: Sodium/hydrogen exchanger (M9PDJ7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSIRTEQDYDSATPALAQQMNLARRACWRIKSYSSESLFKTYASVITDTSANEIDAEAPPPPRDKTKTRIEPQIAPAKRNSSCTSSDWRGMFSKRTLLICALALILGSAQARPNTSAVGVAPRKVSQDIVDAVTQLNLGQSAPIDAVDVGLDPTPSARVPRPEPLKSGDENAKGDEGHKMERYPLSSVDFARVKTPFIIGIWILSASIAKIGFHMTPKLHLIFPESCLLIVVGVVIGVVLYFCTDVAVSPLTPNTFFFYMLPPIILDAGYFMPNRLFFDNLGTILLMAVVGTIFNIATIGGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAVFEEIHVNEILYIVVFGESLLNDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVVALGGTAIGIIWGFLTGLVTRFTDHVRVIEPIFIFVMAYLAYLNAEIFHMSGILAITFCGITMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATVNNMHVWNTWFVVLTIAFCSVFRVIGVILLSALANRFRLHKLSRVDQFVMSYGGLRGAVAFALVLLVDENVVKQKNMFVTTTIAVIYFTVFLQGITIKPLVKILNVKRANKRKPTMNERIHERFMDHLMAGIEDIVGKTGNYNVRDKFKRFDNRFIRPLLIRDLKGAEPKIIETYSKLTMRDAMEVMRRNPSTIGQMTGTESMSALFRNYTNNYIGGRWAPPTIYTTCPSLTNLDNTCSRNLDMAELDYNPSKKDLTDARIHHLLAEELKPYRRHRRLSYSRHAVDDRDLSTQVNYKMQMNFRRMFNDRKHHKRSKRGASNKEAKENVKQNHVSFHDFQQNGTTKQLTNDYINNVLNETAEECQQNPNEINVVGPSDDWDDGLTFTAKSSLAEHPIPEEDRNLSRESDGERRVATPTATESQLPWKRQGDECTDAVQQNEFPAWASNKEYLAYNSPSATFLGGINKPKQPKSVIGLFRRESSSSKAGSVGVGSTGAMDSAASGSETMVVSMSSQPPNAPSTSIHNPRLDKRSQSISSSSLGAGAHQLGPEGHSGPFPVTASHRRNVRRGSMLELSGLIATGRRPSRILQFSPGATNLLGSAMIPSPSPPPPTTSTTTTTTTTTTVKPTSTSTTKNNKTNNSTDTTSASATNSTPTSPNSEDSATYTYHTNGVSIESD
Protein: Protein FAM221B (A6H8Z2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEAHEIIEEPHITMDAEKHPPSKDPSAEDLQENHISESFLKPSTSETPLEPHTSESPLVPSPSQIPLEAHSPETHQEPSISETPSETPTYEASLDSPISVVPEKHLTLPPQSRDYVCLSSSDTLKEDLSSESSSNEVPWTRRSTHLSESESLPEHCLSGPSSQVQVDTTEKQEEEAGEVEKGVDASDSTAHTAQPGHQLGNTARPVFPARQTELVEVAKAMHREEFGAQVNNLFQWEKDAALNAIQTGLYIGWRCPHYLWDCFRIGDESRCFCGHLLREHRIISDISVPCKVSQCRCFMFCFIPSRPEEVGEFWLKRRATFDPKAWRAQCRCKHSHEEHAATGPHPCRHHGCCCGCFESNFLCAACDRRWEEHETFFDTQKTRQRGGRPRGTDTVSNWHRPL
Protein: Uncharacterized protein, isoform D (EC 3.4.11.-) (A0A0B4KH77)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MEGGYVNEEDSDAIMGVESPAIISFTNPKLQIPLMASAIYAPTTITTNTTSTAGTPTSAKNASASASASASASLSSPAGPSAAGSASTSSAPAGGGPWQGLVAKLRNFKLDDTKNIRKRFHFDYISKDRFLGGQLKTKNGQKYVFNGPPSGVYVSKACLIIAAFITVLALLFTIAITYFVTRQGLNPKEVTPPSCITADHPDVNATPIQTAGWVSMNSPPPLQAATPTPMASPTPTNTPTVTTTLAMPASSEKPEIRMVDPKVGDIPVVEPAAGEVEDNTTKPINRPLKLYEGWRPLHYSLLIEPSVATSISNGSLTIEIERDVSKVTSWEPIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNMVDSRLASQDSGLTPRVEIWTRPQFVGMTHYAYKMVRKFLPYYEDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGADLVLRQERYLLPSKNTADQSTWFIPITFETDELRKGDNIPTHWMRSEDEEELIVGNVFAHSSNSDNVIYLNLNRQGYYRVNYDMTSWLALKKNFSTLPRITRAQLLDDALHLSQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYLIYNLKREPAYETFRAFMKFIVRPAFDHYGLHEPDNESHLQLKHRALVAYFACKFNYDRCTQKAQMKFREWMRDPKNNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTTTSASEKEEILTSLGCTTKPWLLSKYLNMTINPTSGILKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSEMIKSLTIYMNKDYHKHQLLDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFLEGIVSEFQINIF
Protein: Uncharacterized membrane protein YIL089W (P40500)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Uncharacterized protein YBL039W-B
- Unfolded protein response-inducible protein 1
- Uncharacterized protein YGR168C
- Uncharacterized protein YKL065W-A
- 2-hydroxyacyl-CoA lyase
- Inner membrane assembly complex subunit 17
Sequence:
MQRTRELESSVAIDQTEVPRSRFFIMVKKLSRVADIVYIVDTFLIPPLHPLKKQHPKVAKFLKVQLVFDLISLFIFATHQLLLLEDGNFGKHYFKRKTKRCSKFSCSRCNANAHHPKWFKFKHSLLCLGTFCFGVYSLVKINKFFKTDQTVDLNRLLELFFWQLNAILNMKLFAFYGDHLESHSAPLDVYEDSFANKSSSGGDEV
Protein: Transcription factor bHLH18 (Basic helix-loop-helix protein 18) (AtbHLH18) (bHLH 18) (Transcription factor EN 28) (bHLH transcription factor bHLH018) (Q1PF17)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor bHLH34
- C2H2 and C2HC zinc fingers superfamily protein
- Transcription factor bHLH115
- C2H2 and C2HC zinc fingers superfamily protein
- Transcription factor ORG2
- Glucose-6-phosphate isomerase, cytosolic
- Transcription factor bHLH11
Sequence:
MNSLVGDVPQSLSSLDDTTTCYNLDASCNKSLVEERPSKILKTTHISPNLHPFSSSNPPPPKHQPSSRILSFEKTGLHVMNHNSPNLIFSPKDEEIGLPEHKKAELIIRGTKRAQSLTRSQSNAQDHILAERKRREKLTQRFVALSALIPGLKKMDKASVLGDAIKHIKYLQESVKEYEEQKKEKTMESVVLVKKSSLVLDENHQPSSSSSSDGNRNSSSSNLPEIEVRVSGKDVLIKILCEKQKGNVIKIMGEIEKLGLSITNSNVLPFGPTFDISIIAQKNNNFDMKIEDVVKNLSFGLSKLT
Protein: Flavodoxin-like fold domain-containing protein (Q9I0Q6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- NAD
- VacJ family lipoprotein
- NAD
- Probable NAD
- FMN-dependent NADH:quinone oxidoreductase 3
- Probable oxidoreductase
- Glutathione-regulated potassium-efflux system protein KefB
- NAD
- Probable oxidoreductase
- Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein
Sequence:
MKNILLLNGGKRFAHSDGRLNQTLHETALAHLDRRGFDLRQTFIDGGYDIPTEVDKFLWADVVIYQMPGWWMGAPWTVKRYIDEVFTAGHGSLYANDGRTRSDSTQKYGSGGLVQGKRYMISATWNAPRQAFDDPSDFFEGKGVDAVYFPFHKANQFLGMSGLPTFLAVDVMKRPDVPATVAAYQAHLDRVFGRAG
Protein: Protein ECERIFERUM 26-like (CER26-like) (CER2-like protein 2) (CER2-like2) (Q9LIS1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in biosynthesis of the epicuticular wax. Plays a role in very-long-chain fatty acid (VLCFA) biosynthesis and is required for VLCFA elongation in leaf. Despite its classification as a BAHD acyltransferase based on sequence homology, CER26L does not seem to share the catalytic mechanism of the members of the BAHD family (By similarity).
Interaction partners:
- Very-long-chain
- Very-long-chain 3-oxoacyl-CoA reductase 1
- 3-ketoacyl-CoA synthase 9
- 3-ketoacyl-CoA synthase 6
- Very-long-chain enoyl-CoA reductase
- Protein ECERIFERUM 2
- GDSL esterase/lipase At5g18430
- GDSL esterase/lipase At1g33811
- 3-ketoacyl-CoA synthase 5
- Phenolic glucoside malonyltransferase 2
Sequence:
MGLVQEEGSGPVHGFRLSTVSASLPSETGTTHEPTGLDLAMKLHYLKAVYIYSAGTARDLTVMDVKAPLFSVFYQIPCIIGRFRRHESGRPYLKCNDCGTRFVESHCDLTVEEWLRVPDRSVDESLVYHQPVGPDLAFSPLLYIQMTRFSCGGLALGLSWAHIMGDPFSLSHFFNLWAQAFAGGKIYCPKTSVTERDFQNPTSTFKKPDSVKQVDLVGDLWVAPNNSKMTTFSFNLTVNDLKTHFPVNGDGEFEILTGIIWKCVATVRGESAPVTITVIRSDPKKLKPRAVRNGQMISSIHVDFSVAEASLEEIVKSIGEAKDERVVIDEIVDDVSDFIVYGANLTFVDMSEVDFYEAKVMGKSPESVYCNVQGIGDDGAVVVLPGVVEEERVVTVTLPVDEIEKVKWEMKKCGLITPLV
Protein: Beaten path IIa (Beaten path IIa, isoform B) (HL05663p) (RE17794p) (Q9BMG9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLELQLCGDLSAGDLSEIPKMGHQRATDTGHRQIRSHRKSDCRTFPARCLLLLLGVLLLSMELVECALRNVNLIIEPPAVRRGQHVVLRCMYDLDGAPLYSAKFYRGQLEFYRYTPGEFPNTKVFPFPGIHVDVSSSNATQVLLRNVGFGLSGNFSCEVTADAPLFSTATAVDTMQVVELPEKRPQVFTEHTRYEPGDVLRANCSTPPSRPRAELTFTINNMVITHVDTEYIRTIDNLIATRISLKMQLQGIHFSSVNPAIYNNVYGLNSVYGHGGPVYAPNSNPGGLLLRCSAQIGDLYQEYKEIELGTPQKDPVPARVTLSSDTSLKNFFSSYFSTSASAASRLLPGVYMAPLIMAMLASLFRLIEAAFEPCDASSQDPQSQTGHSMEHSKERREPKERPALVSSCSVSKASRQQLAWPGSRTESLRLA