wanglab/gogpt-training-data huggingface dataset:
Protein: SWI/SNF complex subunit SWI3 (Transcription factor TYE2) (Transcription regulatory protein SWI3) (P32591)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Subcellular location: Nucleus.
Interaction partners:
- Actin-like protein ARP9
- Transcription regulatory protein SNF2
- SWI/SNF chromatin-remodeling complex subunit SWI1
- SWI/SNF global transcription activator complex subunit SWP82
- Actin-related protein 7
- SWI/SNF chromatin-remodeling complex subunit SNF5
- Transcription regulatory protein SNF12
- Transcription regulatory protein SNF6
- Transcription regulatory protein SNF11
- Transcription initiation factor TFIID subunit 14
Sequence:
MENTLGEGSTVNASVDVDQHGNDNNSDSNANAAVAGVANTDTAGEESQQQDESLKDEATVPNTRDAESEAITVTAKQQPTMQANKLDSQETPSTEESRAQNVFGQDNEDSDNLFGETESSVSNNEANTPSIPTNPVDNENNKPAIKEDSTIQDSNGDVKNMEDVKIQKEEEPENNTVIEGVKEESQPDENTKEMDEVEEDDEDDDQPMISPDNSIFGDTKSESKQLGNTSSVANTPSEIPDAHKAEQEDIIEKTESVDKKVDSGEERNEQEREIMNDHSKSANPKKTTITRVEPETFEIPQAHEIVIPSYSKWFNLEKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNVSGDAAALFRLHKFLTKWGLINYQVDSKLLPKNIEPPLTSQYSTRHDAPRGLFPFESYKPSVQLPDMAKLKKMMNTSDSESTLYKYLKESKRKYDEITHPPSTTDDENGDKNDNGGKMNNEVSTSTSMTGDANLLEEGETSRPLKKVKILEQIDENWSKEDLQKLLKGIQEFGADWYKVAKNVGNKSPEQCILRFLQLPIEDKFLYGDGNGKGDNDNGLGPLKYAPHLPFSKSENPVLSTIAFLVGLVNPKTVQSMTQRAIQSAESIKSQKEEISDQKPIEHIKEGSEIAISSLGYRSHIFATNEERQMNFLTNELIRLQMEKLDAKLNHLKKLEKFMELERKTLERQQENLLIQRLNFNQNSSKIVNVLSKCLNLISDSNINNSSVAEKEEIRSQIDHFKSMLSKPETLSIGKNPFNKPNIETGENHNGQSISNENDVKPISIEAPQFYRYWSA
Protein: Ly49 inhibitory receptor 2 (A0A0G2JTP1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MTEQEVTYTTVRFHKSSVFQNEVRSEETQSAKEIGHRESSVPWKLIVIALGILCSVLLVTVAVLVTNCLQYNHETHELQETQNSQHNCSTMENDIKLKEEMLRNMSIESTRYNALLDLINREQKRWYNKTKTVLAAPQHTGGCVEMHWLCYGIKCYYFIIDKRTCLSFLKIHDKDELKFLQDHIIRDSYWIGLSYNNNKKEWSWIDNTTLNCDLVAMISLHKTGNCKYFSMTGLHDDDCGKRHLCICEKGIEKYPAPLCSVNERSQSAL
Protein: GroES-like family protein (Putative 10kDa chaperonin (CPN10) protein) (Putative 10kd chaperonin) (Q8LDC9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Heat shock 70 kDa protein 10, mitochondrial
- Chaperonin 60 subunit alpha 2, chloroplastic
- Chaperonin CPN60-like 2, mitochondrial
- Purine-uracil permease NCS1
- Chaperonin CPN60-like 1, mitochondrial
- 10 kDa chaperonin 1
- Chaperonin 60 subunit beta 4, chloroplastic
- Chaperonin 60 subunit beta 3, chloroplastic
- Chaperonin 60 subunit beta 2, chloroplastic
- Chaperonin 60 subunit alpha 1, chloroplastic
Sequence:
MAKRLIPTLNRVLVEKILPPSKTVSGILLPEKSSQLNSGRVIAVGPGARDRAGNLIPVSVKEGDNVLLPEFGGTQVKLGEKEFLLYRDEDIMATLHE
Protein: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Cobalamin-independent methionine synthase) (Methionine synthase, vitamin-B12 independent isozyme) (P82610)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
Interaction partners:
- Adenosylhomocysteinase
- S-adenosylmethionine synthase
- S-adenosylmethionine-homocysteine S-methyltransferase
- Cystathionine beta-lyase
- cystathionine gamma-synthase
- cystathionine gamma-lyase
- Homocysteine/cysteine synthase
- Cystathionine beta-synthase
- Homoserine dehydrogenase
- Methylenetetrahydrofolate reductase
Sequence:
MVQSSVLGFPRIGGQRELKKITEAYWSGKATVEELLAKGKELREHNWKLQQKAGVDIIPSNDFSYYDQVLDLSLLFNAIPERYTKFDLAPIDVLFAMGRGLQKKATETQAAVDVTALEMVKWFDSNYHYVRPTFSHSTEFKLNTAAGIKPVDEFNEAKALGVQTRPVILGPVSYLYLGKADKDSLDLEPISLLPKILPVYKELLQKLKEAGAEQVQIDEPVLVLDLPEAVQSKFKEAYDALVGADVPELILTTYFGDVRPNLKAIENLPVAGFHFDFVRVPEQLDEVASILKDGQTLSAGVVDGRNIWKTDFAKASAVVQKAIEKVGKDKVVVATSSSLLHTPVDLESETKLDAVIKDWFSFATQKLDEVVVIAKNVSGEDVSKQLEANAASIKARSESSITNDPKVQERLTTINEALATRKAAFPERLTEQKAKYNLPLFPTTTIGSFPQTKDIRINRNKFAKGQITAEEYEAFINKEIETVVRFQEEIGLDVLVHGEPERNDMVQYFGEQLNGFAFTTNGWVQSYGSRYVRPPIIVGDVSRPKAMTVKESVYAQSITSKPMKGMLTGPVTILRWSFPRDDVSGKIQALQLGLALRDEVNDLEGAGITVIQVDEPAIREGLPLRAGKERSDYLNWAAQSFRVATSGVENSTQIHSHFCYSDLDPNHIKALDADVVSIEFSKKDDPNYIQEFSEYPNHIGLGLFDIHSPRIPSKQEFVSRIEEILKVYPASKFWVNPDCGLKTRGWPEVKESLTNMVEAAKEFRAKY
Protein: Putative 8-amino-7-oxononanoate synthase 2 (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (KAPA synthase) (8-amino-7-ketopelargonate synthase) (P9WQ85)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
Interaction partners:
- Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
- Probable acyl carrier protein AcpA
- Uncharacterized protein Rv0034
- Probable fatty-acid-CoA ligase FadD34
- 8-amino-7-oxononanoate synthase 1
- Dethiobiotin synthetase BioD
- Biotin synthase
- PPE family protein PPE35
Sequence:
MPTGLGYDFLRPVEDSGINDLKHYYFMADLADGQPLGRANLYSVCFDLATTDRKLTPAWRTTIKRWFPGFMTFRFLECGLLTMVSNPLALRSDTDLERVLPVLAGQMDQLAHDDGSDFLMIRDVDPEHYQRYLDILRPLGFRPALGFSRVDTTISWSSVEEALGCLSHKRRLPLKTSLEFRERFGIEVEELDEYAEHAPVLARLWRNVKTEAKDYQREDLNPEFFAACSRHLHGRSRLWLFRYQGTPIAFFLNVWGADENYILLEWGIDRDFEHYRKANLYRAALMLSLKDAISRDKRRMEMGITNYFTKLRIPGARVIPTIYFLRHSTDPVHTATLARMMMHNIQRPTLPDDMSEEFCRWEERIRLDQDGLPEHDIFRKIDRQHKYTGLKLGGVYGFYPRFTGPQRSTVKAAELGEIVLLGTNSYLGLATHPEVVEASAEATRRYGTGCSGSPLLNGTLDLHVSLEQELACFLGKPAAVLCSTGYQSNLAAISALCESGDMIIQDALNHRSLFDAARLSGADFTLYRHNDMDHLARVLRRTEGRRRIIVVDAVFSMEGTVADLATIAELADRHGCRVYVDESHALGVLGPDGRGASAALGVLARMDVVMGTFSKSFASVGGFIAGDRPVVDYIRHNGSGHVFSASLPPAAAAATHAALRVSRREPDRRARVLAAAEYMATGLARQGYQAEYHGTAIVPVILGNPTVAHAGYLRLMRSGVYVNPVAPPAVPEERSGFRTSYLADHRQSDLDRALHVFAGLAEDLTPQGAAL
Protein: Choline O-acetyltransferase (CHOACTase) (ChAT) (Choline acetylase) (EC 2.3.1.6) (P28329)
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
Interaction partners:
- Vesicular acetylcholine transporter
- Acetylcholinesterase
- Glycerophosphocholine phosphodiesterase GPCPD1
- Choline kinase alpha
- Choline/ethanolamine kinase
- Phosphoethanolamine/phosphocholine phosphatase
- Tyrosine 3-monooxygenase
- Cholinesterase
- Kinesin-associated protein 3
- Protachykinin-1
Sequence:
MGLRTAKKRGLGGGGKWKREEGGGTRGRREVRPACFLQSGGRGDPGDVGGPAGNPGCSPHPRAATRPPPLPAHTPAHTPEWCGAASAEAAEPRRAGPHLCIPAPGLTKTPILEKVPRKMAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHVTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
Protein: Ig mu chain C region membrane-bound form (P23735)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:2119496}; Single-pass membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000269|PubMed:2119496}.
Interaction partners:
Sequence:
VQSAPKSLFPVWQCGSASDGLVTLGCVTRDLASADGLSFIWKDASGSALTDVVQYPAVQATGGYTSVSHVRVKASDWNGNKKFTCEVKNGLGSKDASLQKPVERELHASLLLTTPTQTEIDNGTATFVCLATPFSPKSHTFKWTLEKTDISNKVKENIVSQNKGNFTAISVLELSASEWTSSTSPVKCEFQQKNHNVFKEASYGNPEFPKVYLLAPPESSGESVTLTCYVKDFYPKEVAVSWLVNDKQVEEVVGYEQNTTAVIDRNNLFSVYSQLIIKTADWNSGSVFSCLVYHESIKDCVRHISRSIAKDSKTPTLVNLTLTNPQSCSCSTYVCIWSTEIFHYEMEMDDDNMANTALTFVFLFLITLFYSIGVTVFKVK
Protein: Ubiquitin-like protein MDY2 (Golgi to ER traffic protein 5) (Mating-deficient protein 2) (Translation machinery-associated protein 24) (Q12285)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos.
Subcellular location: Cytoplasm, cytosol. Nucleus. Note=Detected in both cytosol and nucleus but is predominantly cytosolic.
Interaction partners:
- Golgi to ER traffic protein 4
- Small glutamine-rich tetratricopeptide repeat-containing protein 2
- ATPase GET3
- Maintenance of telomere capping protein 1
- UPF0303 protein YBR137W
- Mitochondrial protein import protein MAS5
- Heat shock protein 104
- Golgi to ER traffic protein 1
- 26S proteasome regulatory subunit RPN10
- Golgi to ER traffic protein 2
Sequence:
MSTSASGPEHEFVSKFLTLATLTEPKLPKSYTKPLKDVTNLGVPLPTLKYKYKQNRAKKLKLHQDQQGQDNAAVHLTLKKIQAPKFSIEHDFSPSDTILQIKQHLISEEKASHISEIKLLLKGKVLHDNLFLSDLKVTPANSTITVMIKPNPTISKEPEAEKSTNSPAPAPPQELTVPWDDIEALLKNNFENDQAAVRQVMERLQKGWSLAK
Protein: Acetyltransferase GNAT family protein (Orf14) (Q8KRB5)
Organism: Streptomyces clavuligerus
Interaction partners:
- DUF482 domain-containing protein
- Biotin carboxylase
- ABC-type dipeptide transport system, solute-binding protein
Sequence:
MNDTAGELEFVPLAANDDETVGQWLDLMALAAETGPRAAPPCNVDMVGSLRFAPPATALDDWVVRSGGRVVGALRLALPDGAPTARVDQLLVHPGRRRRGIGRALWAHARELARKHDRTTLTATVVESLPSGPAQDPGPAAFAAAMGAHRSDIPAGTHQWLDLDRHDPLADGVPAVPAGYSLVTWGTITPDEYAVPVSELELSLGAGPVDRAAQEVRTSYARQFETMRVGRGRRAYHTGAVHDATGALAGYTSVSKTTGNPAYALQGMTVVHREHRGHALGTLLKLANLEYVLRHEPEVRLVETANAEDNHPMIAVNAALGFEPYDRWVFWTAEAGPSD
Protein: Interleukin 25 (D3ZLB1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Interleukin 17 receptor B
- Interleukin-17 receptor A
- Interleukin-17 receptor E
- Interleukin 17D.
- Interleukin-17F
- Interleukin-17A
- Thymic stromal lymphopoietin
- Interleukin-33
- Interleukin-17 receptor D
Sequence:
MYQAVAFLAMVVGTHTVSLRIQEDCSHLPRCCPSKQQEFPEEWLKWNPAPVSPPEPLRHTHHPESCRASKDGPLNSRAISPWSYELDRDLNRVPQDLYHARCLCPHCVSLQTGSHMDPMGNSVPLYHNQTVFYRRPCHGEQGAHGRYCLERRLYRVSLACVCVRPRMMA
Protein: WHAMM and JMY related, isoform B (Q0KI93)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Actin-related protein 2
- Actin-related protein 3
- Cdc42-interacting protein 4, isoform B
- Actin-related protein 2/3 complex subunit
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 2
- Amphiphysin
- Actin-related protein 2/3 complex subunit 5
- Actin-related protein 2/3 complex subunit 4
Sequence:
MEDYTYAYISEPVEFRQLEGNAIDFRKTFDLRGQGTDEMLQLYLRKANLSDDLERLPAIVRRAYVYDIIRSNKEPGYWVVISCSISSCQLHQPKVSLMLSTVVLNAAVFFSFQPPSMQVSSDVFAHPPPAVRPPPHYADNVSINASLDGMKSSSSSNSLDRYLGAPPSVALAGPSFATSVLVSSKGSKYEISGPVNFQHVSGDVTRDRTRNAFDLNADPNDKVLRKYMMERGITEADISDMRRQEVIKKIIHSNFTWMPPKSDLQAQPKVQDHARPLLYATISTNNQITPPPSPPPPPIATISRPTEAPNFSNYASLTSRFVDISDMDLPAPTPAAPTPFQPAEVGSVIPVQVQPQQSVKPKVPPPPSAVMAKNTHGYPAAIDIRQVRPSVAPKVANETYATISPQRKVGSMRVPPPAPPKPTIVPHTNSTISNGSLYAVSPVQYAPVAKPAPPAAPAKPTSRSSAVYMTPLSAQKTQISSTPVPVSPPPPTAASVGVPPPPPAPPAGVPPAPPPMPVFGAGGAPPPPPPPSSGMAGVPPPPPMQKSQPKAVSAASTGGDPRDAFLESIRQGVKLKKVDQKAATISGIKPRPERKPVTTDFLSELKLGITLRRVKNPADNPYSEESESQA
Protein: Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) (Q54VA2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Catalyzes the reversible stereospecific interconversion of fumarate to L-malate.
Subcellular location: [Isoform Mitochondrial]: Mitochondrion {ECO:0000250|UniProtKB:P07954}.; SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm {ECO:0000250|UniProtKB:P07954}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit
- NADP-dependent malic enzyme
- Succinate dehydrogenase cytochrome b small subunit
- Probable malate dehydrogenase 2, mitochondrial
- Probable malate dehydrogenase 3
- Probable malate dehydrogenase 1
- Aspartate aminotransferase, mitochondrial
- Aspartate aminotransferase, cytoplasmic
Sequence:
MLSASRKLNNQQFLKTIRNMTTFRSEFDTFGEVKVNDEKYWGAQTQRSLENFDIGGESEKMPLMVVRSFGILKRCAAIVNKKYGLDATIADNIAKAATEVVEGKLDDQFPLVVFQTGSGTQSNMNANEVISNRAIELMTGKRDFSKKLVHPNDHVNKSQSSNDTFPTCMHIAAAISINEKLVPALEMLLAAMRTKQNEFNHIIKIGRTHLQDATPLTLGQEFSGYCTQIEYGIQRIKDTLPRLYNLAQGGTAVGTGLNTPVGFDVDIASEVAKFTGLPFKTAPNKFEALAAHDAMVEVSGALNTVAVSLMKIANDIRFLGSGPRCGLGELILPENEPGSSIMPGKVNPTQCEAMTMVCAQVMGNNTTVSIAGSNGHFELNVFKPVIIKNVLSSIRLIADASVSFTKHCVVGIKADEKRIDQLLHESLMLVTALNPYIGYDKAAKAAKKAHKEKTTLKEACLSLGFTTSEEFDKWVDPSKMIGSMK
Protein: Sodium-coupled neutral amino acid transporter 5 (Solute carrier family 38 member 5) (System N transporter 2) (Q8WUX1)
Organism: Homo sapiens (Human)
Function: Symporter that cotransports neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Releases L-glutamine and glycine from astroglial cells and may participate in the glutamate/GABA-L-glutamine cycle and the NMDA receptors activation (By similarity). In addition, contributes significantly to L-glutamine uptake in retina, namely in ganglion and Mueller cells therefore, participates in the retinal glutamate-glutamine cycle (By similarity). The transport activity is pH sensitive and Li(+) tolerant. Moreover functions in both direction and is associated with large uncoupled fluxes of protons (By similarity). The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+) (By similarity). May have a particular importance for modulation of net hepatic glutamine flux (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:A2VCW5}; Multi-pass membrane protein {ECO:0000255}. Note=Localized at astroglial membrane. {ECO:0000250|UniProtKB:A2VCW5}.
Interaction partners:
- Sodium-coupled neutral amino acid transporter 3
- tRNA
- Phosphatidylcholine transfer protein
- Sodium channel protein type 11 subunit alpha
- Neutral amino acid transporter B
Sequence:
MELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSRMSGH
Protein: Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) (C7G3A0)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:19837036}; Multi-pass membrane protein {ECO:0000269|PubMed:19837036}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:19837036}; Multi-pass membrane protein {ECO:0000269|PubMed:19837036}. Note=Also localizes to endoplasmic reticulum exit site.
Interaction partners:
Sequence:
MALVRWRLRRGNFHLLSRVLLLKLTVVIISVLLFCEYFIYHLVIFQCHWPEVKTLAHGDRQKPVLKAMFLADTHLLGEIRGHWLDKLRREWQMERAFQTALWWLQPEVIFILGDIFDEGKWSTTEAWADDVQRFRKIFRHGSHVQLKVVIGNHDIGFHYQMSKYRIKRFEKVFSSERLFSWKGVNFVMVNSVAMEGDGCSICSEAEAELREISRKLNCSREVQGSSQCEGEQRLPFSAPVLLQHYPLYRASDANCSGEDAAPPEERNVPFEEKYDVLSREASQKLLWWLQPRLVLSGHTHSACEVLHPGGVPEVSVPSFSWRNRNNPSFIMGSLTSKDYALSKCYLPFEDRVLATYGAAAVFLVVLILAHLERLPSSFLFGWKLRKMHMRG
Protein: LIM domain-containing protein PLIM2c (Pollen-expressed LIM protein 2C) (Q500W4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. Associates predominantly with long and dynamic actin bundles in the shank of growing pollen tubes. The actin regulatory activities are inhibited by pH > 6.8 and/or high [Ca(2+)].
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20817848}.
Interaction partners:
- Fimbrin-5
- Actin cross-linking protein, putative
- Propionyl-CoA carboxylase
Sequence:
MAAFTGTTDKCKACDKTVYVMDLMTLEGMPYHKSCFRCSHCNGTLVICNYSSMDGVLYCKTHFEQLFKESGNFSKNFQTAGKTEKSNDATKAPNRLSSFFSGTQDKCAACKKTVYPLEKMTMEGESYHKTCFRCAHSGCPLTHSSYAALDGVLYCKVHFSQLFLEKGNYNHVLQAAANHRRSTAEEDKTEPKEDEANPTEEETSDAAAEEHES
Protein: Uncharacterized protein YagA (P37007)
Organism: Escherichia coli (strain K12)
Interaction partners:
- tRNA-uridine aminocarboxypropyltransferase
Sequence:
MESLMPWDARDTMSLRTEFVLFASQDGANIRSLCRRFGISPATGYKWLQRWAQEGAAGLQDRPRIPHHSPNRSSDDITALLRMAHDRHERWGARKIKRWLEDQGHTMPAFSTVHNLMARHGLLPGASPGIPATGRFEHDAPNRLWQMDFKGHFPFGGGRCHPLTLLDDHSRFSLCLAHCTDERRETVQQQLVSVFERYGLPDRMTMDNGSPWGDTTGTWTALELWLMRLGIRVGHSRPYHPQTQGKLERFHRSLKAEVLQGKWFADSGELQRAFDHWRTVYNLERPHEALDMAVPGSRYQPSARQYSGNTTPPEYDEGVMVRKVDISGKLSVKGVSLSAGKAFRGERVGLKEMQEDGSYEVWWYSTKVGVIDLKKKSITMGKGC
Protein: Putative uncharacterized protein YOL114C (Q12322)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein bL33m
- Ribosome-recycling factor, mitochondrial
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL2m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein mS29
Sequence:
MTTLMGKFKLTGRSPLFVLQPMLHCKKQQFVEEAVRLISNKKIGKKSDFVQARNWVGALNVTGLPLNQFILRYDRASGPGGQNVNKVNSKCTLTLSGLSNCAWIPQEVRNILSSGRFRYYAKGSDSIVIQSDETRSRETNKLKCFEKLVQEIRQTCQFPNDTTAETSKKWNKIKEKANKERLLDKKVHSDKKKNRSKIKFNY
Protein: Fidgetin (Q5HY92)
Organism: Homo sapiens (Human)
Function: ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome.
Subcellular location: Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22672901}. Note=Localizes to centrosomes throughout mitosis and to the spindle midzone during telophase.
Interaction partners:
Sequence:
MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
Protein: 4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8) (Q5HG24)
Organism: Staphylococcus aureus (strain COL)
Function: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00102}.
Interaction partners:
Sequence:
MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKGADVAIDFSNPNLLFPLLDEDFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
Protein: L-asparaginase 2 (EC 3.5.1.1) (L-asparaginase II) (L-ASNase II) (L-asparagine amidohydrolase II) (Colaspase) (P00805)
Organism: Escherichia coli (strain K12)
Subcellular location: Periplasm.
Interaction partners:
- Aspartate ammonia-lyase
- L-asparaginase 1
- Isoaspartyl peptidase
- Asparagine synthetase B
- L-aspartate oxidase
- Aspartate aminotransferase
- Argininosuccinate synthase
- Aspartate carbamoyltransferase catalytic subunit
- Adenylosuccinate synthetase
- Aspartate carbamoyltransferase regulatory chain
Sequence:
MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATKSNYTVGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKTDGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAADKASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARKHTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVFDTLATAAKTGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQTKDPQQIQQIFNQY
Protein: Ribosome-recycling factor (Q8IFQ7)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Mitochondrial ribosomal protein L20, putative
- Ribosomal protein L27, putative
- Ribosomal protein S16, mitochondrial, putative
- 50S ribosomal protein L19
- 40S ribosomal protein S11
- 40S ribosomal protein S5, putative
- 60S ribosomal protein L6, putative
- 60S ribosomal protein L11a, putative
- 60S ribosomal protein L23
- 60S ribosomal protein L35, putative
Sequence:
MYGGNNLRKFIPLVDIPLLGNKNNLLIFCGKVNFGSKKQKEKVDKETKKFRKFLKISNMKNNDEDEKYEGDINEGDMKKKMKGISGMTRIDYKIYDIKIQEINKNFENKIKKIFDTCLQIDFFNNISILKDKKNIKLCDVAQVVIKSSNLIYFYPYTINDIQKIIHNLKLKDNTWNPTVSNDGQYVILQIQPLSEDVKMKKKKEAKDLFEKIKNDIRNVRYKIRDDIIKNIEGDQWKIVERNKLDNYIKDKMKLIENVYEQSVKNY
Protein: Cyb5p (A0A1D8PQP7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004131}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004131}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004131}. Microsome membrane {ECO:0000256|ARBA:ARBA00037877}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00037877}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00037877}.
Interaction partners:
- NADH-cytochrome b5 reductase 1
- Putative lipase ATG15
- NADH-cytochrome b5 reductase
- NADH-cytochrome b5 reductase 2
- Lanosterol 14-alpha demethylase
- C-22 sterol desaturase ERG5
- NADPH--cytochrome P450 reductase
Sequence:
MSEETVTIYDYEEVSKHRTHDDLWVVLNGKVYNISSYIDEHPGGEEVILDVAGEDATEAFDDIGHSDEAHEILQKLYIGNLKGAKPVEAKHAQSYATEDSGINFPLIAVGVFLLAFGAYYYKTNFA