wanglab/gogpt-training-data huggingface dataset:
Protein: Fluconazole resistance protein 1 (P38124)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable efflux transporter. Confers resistance to the azole derivative fluconazole (FCZ).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein HOL1
- Aminotriazole resistance protein
- AP-1-like transcription factor YAP1
- Zinc finger transcription factor YRR1
- Protein SNQ2
- Transcription factor PDR3
- Transcription factor PDR1
- Azole resistance protein 1
- Glutathione S-transferase 2
Sequence:
MVYTSTYRHTIVVDLLEYLGIVSNLETLQSAREDETRKPENTDKKECKPDYDIECGPNRSCSESSTDSDSSGSQIEKNDPFRVDWNGPSDPENPQNWPLLKKSLVVFQIMLLTCVTYMGSSIYTPGQEYIQEEFHVGHVVATLNLSLYVLGYGLGPIIFSPLSETARYGRLNLYMVTLFFFMIFQVGCATVHNIGGLIVMRFISGILCSPSLATGGGTVADIISPEMVPLVLGMWSAGAVAAPVLAPLLGAAMVDAKNWRFIFWLLMWLSAATFILLAFFFPETQHHNILYRRALKLRKETGDDRYYTEQDKLDREVDARTFLINTLYRPLKMIIKEPAILAFDLYIAVAYGCFYLFFEAFPIVFVGIYHFSLVEVGLAYMGFCVGCVLAYGLFGILNMRIIVPRFRNGTFTPEAFLIVAMCVCWCLPLSLFLFGWTARVHWILPVISEVFFVLAVFNIFQATFAYLATCYPKYVASVFAGNGFCRASFACAFPLFGRAMYDNLATKNYPVAWGSSLVGFLTLGLAIIPFILYKYGPSLRTRSSYTEE
Protein: histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (A0A2R8Y3N3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAVLTSQLKAHQEKPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
Protein: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (O60262)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-4
- Guanine nucleotide-binding protein subunit beta-5
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
Sequence:
MSATNNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFKDKKPCIIL
Protein: Inclusion membrane protein A (A0A0H3MD02)
Organism: Chlamydia trachomatis serovar L2 (strain ATCC VR-902B / DSM 19102 / 434/Bu)
Function: Chlamydia replicate within a host intracellular vacuole, termed an inclusion, which is formed by fusion of many smaller inclusion bodies. IncA may be involved in the homotypic fusion of inclusions; injection of anti-IncA antibodies prevents homotypic fusion, but not fusion with exocytic vesicles.
Subcellular location: Secreted {ECO:0000305|PubMed:10447885}. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane {ECO:0000269|PubMed:10447885, ECO:0000269|PubMed:9826388, ECO:0000305|PubMed:11402010}; Multi-pass membrane protein {ECO:0000255}. Note=Secreted, probably by a type III secretion system (Probable). Secretion into the host pathogen-containing vacuole membrane (inclusion body) is considerably decreased when infected HeLa cells are grown at 32 degrees Celsius (PubMed:12065525). Localized in the inclusion membrane (Probable) (PubMed:11207546, PubMed:9826388). Inclusion membrane staining is punctate (PubMed:10447885). In the inclusion, the C-terminus faces the host cytosol (PubMed:11207546). {ECO:0000269|PubMed:10447885, ECO:0000269|PubMed:11207546, ECO:0000269|PubMed:12065525, ECO:0000269|PubMed:9826388, ECO:0000305|PubMed:11402010, ECO:0000305|PubMed:12694613}.
Interaction partners:
Sequence:
MTTPTLIVTPPSPPAPSYSANRVPQPSLMDKIKKIAAIASLILIGTIGFLALLGHLVGFLIAPQITIVLLALFITSLAGNALYLQKTANLHLYQDLQREVGSLKEINFMLSVLQKEFLHLSKEFATTSKDLSAVSQDFYSCLQGFRDNYKGFESLLDEYKNSTEEMRKLFSQEIIADLKGSVASLREEIRFLTPLAEEVRRLAHNQESLTAAIEELKTIRDSLRDEIGQLSQLSKTLTSQIALQRKESSDLCSQIRETLSSPRKSASPSTKSS
Protein: Krueppel-like factor 2 (Lung krueppel-like factor) (Q9Y5W3)
Organism: Homo sapiens (Human)
Function: Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Nuclear factor NF-kappa-B p105 subunit
- Transcription factor p65
- Sphingosine 1-phosphate receptor 1
- C-C chemokine receptor type 7
- Transcription factor SOX-2
- L-selectin
- Granzyme B
- Histone acetyltransferase p300
- Myc proto-oncogene protein
- POU domain, class 5, transcription factor 1
Sequence:
MALSEPILPSFSTFASPCRERGLQERWPRAEPESGGTDDDLNSVLDFILSMGLDGLGAEAAPEPPPPPPPPAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPLGPALHGRFLLAPPGRLVKAEPPEADGGGGYGCAPGLTRGPRGLKREGAPGPAASCMRGPGGRPPPPPDTPPLSPDGPARLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAPPAFGLFDDAAAAAAALGLAPPAARGLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM
Protein: Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1) (Q7K237)
Organism: Drosophila melanogaster (Fruit fly)
Function: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q9JJ05}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Polypeptide N-acetylgalactosaminyltransferase 35A
- N-acetylgalactosaminyltransferase 6
- N-acetylgalactosaminyltransferase 4
- Putative polypeptide N-acetylgalactosaminyltransferase 9
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase P
- Polypeptide N-acetylgalactosaminyltransferase 3
- Polypeptide N-acetylgalactosaminyltransferase 5
Sequence:
MTANSLLGRSILNEGRSNKRSFVSLIVGLIVGFCLAELFVYSTPERSEFMPYDGHRHGDVNDAHHSHDMMEMSGPEQDVGGHEHVHENSTIAERLYSEVRVLCWIMTNPSNHQKKARHVKRTWGKRCNKLIFMSSAKDDELDAVALPVGEGRNNLWGKTKEAYKYIYEHHINDADWFLKADDDTYTIVENMRYMLYPYSPETPVYFGCKFKPYVKQGYMSGGAGYVLSREAVRRFVVEALPNPKLCKSDNSGAEDVEIGKCLQNVNVLAGDSRDSNGRGRFFPFVPEHHLIPSHTDKKFWYWQYIFYKTDEGLDCCSDNAISFHYVSPNQMYVLDYLIYHLRPYGIINTPDALPNKLAVGELMPEIKEQATESTSDGVSKRSAETKTQ
Protein: carboxylesterase (EC 3.1.1.1) (Q961N0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEVQVGWPKLIKMGAQLVGHKVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISHDLEMRDLPESDCLAVWDTFYPRESLF
Protein: FERM domain containing kindlin 2 (A0A0U1RRM8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XALELEGPLITPGSGTDVLYIGPLKGSIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWAILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQEKGCKKHMPGYIRDLITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV
Protein: Innexin inx3 (Innexin-3) (Q9VAS7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Structural components of the gap junctions. Essential for proper epithelial development of the epidermis.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction. Cytoplasm. Lateral cell membrane. Apicolateral cell membrane. Note=In ovary, localizes to the lateral membrane of follicle cells covering the oocyte and to the apicolateral membrane of follicle cells covering the nurse cells. In nurse cells, localizes to the membrane and around the nuclei.
Interaction partners:
- Innexin inx1
- Innexin inx2
- LD15563p
- Serine/threonine-protein kinase par-1
- GEO04221p1
Sequence:
MAVFGMVSAVSGFIKIRYLLDKAVIDNMVFRCHYRITTAILFTCCIIVTANNLIGDPISCINDGAIPMHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQEKRYHSYYQWVPFVLFFQGLMFYVPHWVWKNMEDGKIRMITDGLRGMVSVPDDYRRDRQDRILKYFVNSLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTDVLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVLYSLVVIMMPTTRETIIKRSYRSAQRKEIAGLVRRLEIGDFLILHFLSQNLSTRSYSDMLQQLCGLLGASRTPSAPSTLEMNRISHPIYPPVETFGGGKETET
Protein: Tumor protein 63 (p63) (Q8JFE3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU003304}.
Interaction partners:
Sequence:
MLYLETNAPSSYSEPQYTSLGLLNSMDQNGGSTSTSPYNNDHAQNNVTAPSPYAQPSSTFEALSPSPAIPSNTDYAGPHTFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVLTNPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNDGQIAPPSHLIRVEGNSHAQYVEDSITGRQSVLVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQHVTDGTKSSEAFRQASSHLSQLNSIKKRRSTDEEVFCLPIKGREIYEILVKIKESLELMQFLPQQTIESYRQQQQNLLQKQSSLPPQPAFGSSSPTLGKNKLPSVSQLINPQQRNALTPSGMPGGLTDMTPPMMGGPVPMNTDLSSLSPNNPLQSQLQMVPSSHCTPPPPYPMDNSISSFLLRLGCSACLDYFTAQGLTNIYQIENYNLEDLSRLKIPTEFQHIIWKGIMEYRQTMEFSPPPHILRTSSGTSTVSVGSTEARGERVIDAVRFTLRQTISFPPRDDWTDFSFDLAPDSRRNKQQRIKEEGE
Protein: Photosystem I P700 chlorophyll a apoprotein A1 (EC 1.97.1.12) (PSI-A) (PsaA) (P56766)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00458}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00458}.
Interaction partners:
- Photosystem I reaction center subunit IV A, chloroplastic
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I reaction center subunit II-2, chloroplastic
- Photosystem I reaction center subunit XI, chloroplastic
- Photosystem I reaction center subunit psaK, chloroplastic
- Photosystem I reaction center subunit III, chloroplastic
- Photosystem I reaction center subunit VIII
- Photosystem I reaction center subunit IX
- Photosystem I iron-sulfur center
- Photosystem I reaction center subunit V, chloroplastic
Sequence:
MIIRSPEPEVKILVDRDPIKTSFEEWAKPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYSEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGIKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIIVAHHMYSMPPYPYLATDYATQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTNRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGVTAPGETASTSLTWGGGELVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG
Protein: Zinc finger transcription factor detour (Q800Z9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPVDMQPHQGLYHYDNTSNQPSRGLAPSVRSPYSSEASSVCVALSGGQSVNSREMYNPSMAPGACMEPYMRAPHAPPPHSMMGHRGMPPPEGMSGAPYCNQNMMTSHHNLPHNQHTSELMASGDASCFSTPRSMLKLSKKRALSISPLSDASVDLQTVIRTSPNSLVAFVNSRCGPNNPSSYGHLSVGTMSPSLGFSSSINYSRPQGNIYSHPVPSCIGAPARLPPHNPRLHTPAKHTHLKTEPVLGSVMDSINIKGLEDHSEGDVASPSSTGTQDPLLGLLEGRDDLDKEEKPEPEAIYETNCHWESCSKEFDTQEQLVHHINNEHIHGEKKEFVCHWKDCSREQRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDTGPRPPGLTTAGQSSELLIEKEERNREDCKLLAPDNTLKSQPSPGGQSSCSSERSPLGSANNNDSGVEMNLNAAGSLEDLTTQEDSGNAGVSESSATISSGGMCMSVQALKRLENLKIDKLKQIRRPTPPGRNAGNKLPALSATGEMMSMCAPSPLLSNRRVMELSAPDMGGVTGMSCPPNDRRGSGTSSLSSAYTVSRRSSMVSPYLSSRRSSDVSHCQSVMGGEVPGDPLSPQNSQRAGLCQNSGGLPGLPSLTPAQQYSLKAKYAAATGGPPPTPLPNMDQAGTPARHVGFLRECQGQPLPPFLQQGGTRRHSANAEYGTGVIYPHQAPGNNTRRASDPVRSAADPQGLPKVQRFNSLSNVSLMSRRNALQQCGSDAALSRHMYSPRPPSITENVMMEAMGMDGNTEGRQQGNMIPGGDRSYMGYQHNPHQASQLSPGQESLGCIDQVYQSQMQGQYQREESCSTGVMGQADIANNLLQQAEYGMSTCQLSPSGPHYPSQGDGSGPWGQTNQLHSPGMQYQGAGMQGQHYTQQGIYDPTSNPNLQRVTVKPEQFHPSMGGSSSCQNTKALHQNRHNANMQTYPLQGQGIMNRSSSASCDFHHSQMGTQPNQGGSFQSGTGINLALAESRRSQTPMHQMKEMMVRNYVQSQQALLWEQQQEQSVSEKPDGMDMGQTQMMQHSPQHQQANQNLYPGNTYQGYPNQNLMSPQQNRVPGSVKEQMQSSCYGPDMIPRPPQVRKSLSRQNSLSQQAGGAYLGSPPHLSPVHSTASPRRGVRLPPVQQQQQQQQQHSENFNNNNNPMYYSGQMHMHHDLEKTPEGPCLAQQHLTSSDPTTKPTSISYPDPAPMSNALEHLDLENAQIDFTSIIDDQEPSSYSPINAPIGHNQCSSQTSSRLTTPQNSITLPSGLSNMAIGDMSSMLTSLAGENKYLNTLS
Protein: Nuclear pore complex protein Nup85 (J3QL54)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567, ECO:0000256|RuleBase:RU365073}.
Interaction partners:
Sequence:
MEEMHQVAIAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKELLSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS
Protein: Glycogen synthase kinase-3 beta (EC 2.7.11.26) (H0ZT29)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Catenin beta 1
- Axin-1
- APC regulator of WNT signaling pathway
- Dishevelled segment polarity protein 3
- Dishevelled segment polarity protein 1
- non-specific serine/threonine protein kinase
- RAC-alpha serine/threonine-protein kinase
- Cyclin D1
- Tuberin
- Casein kinase I isoform alpha
Sequence:
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPMIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDKPALFNFTTQELSSNPSLASILIPAHARNQAAASTPTNATAASDVNAGERVQTNSVATASASNST
Protein: N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Q5FWF5)
Organism: Homo sapiens (Human)
Function: Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
Subcellular location: Nucleus {ECO:0000269|PubMed:14576321, ECO:0000269|PubMed:15958495}. Chromosome {ECO:0000269|PubMed:15958495}. Note=Nuclear at interphase, associated with chromosomes during mitosis. {ECO:0000269|PubMed:15958495}.
Interaction partners:
- Structural maintenance of chromosomes protein 3
- Sister chromatid cohesion protein PDS5 homolog A
- Wings apart-like protein homolog
- Chromosome transmission fidelity protein 18 homolog
- Double-strand-break repair protein rad21 homolog
- Cohesin subunit SA-1
- Chromosome transmission fidelity protein 8 homolog
- Sister chromatid cohesion protein PDS5 homolog B
- Sister chromatid cohesion protein DCC1
- Glycine N-acyltransferase-like protein 1
Sequence:
MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST
Protein: Glucosidase 2 subunit beta (Q802Z2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTCVHLLLTLVFAVSLGTPVEVHRPRGVPLSKKPFYEENKPFTCLDGSKTILFDQVNDDYCDCKGGSDEPGTAACPNGKFHCTNAGYKPTFIPSSRINDGICDCCDTTDEYNSGAKCENTCKELGRKEREVLQKMAEITKEGFLLKQQLIEEAKKGRGEKQSKVTEMQDNKKQLEEKVEALRTVKETAEQPEREAKERHLKAWEEQKAAIRLVKDKAKMAEAFLELDDNADGLVSVSELQSHAELDSDTDGTLSEAEAKGLMGGVEQVDTATFESVWENIKDKYHSESQPEEPAPVETPVDEVKEPVVDNESEPYPEDISEEEDEDDDDDDEYHEEDEKAPPTMKTPEKSQEDEEAMPPYEADTQVLIEAAQKARDDFEEAEKALREMDDQIRNIEKELSFDFGPNAEFTYLYSQCYELSTSEYIYRLCPFNRVSQKPKFGGSETNLGTWGSWSGPENNKYLSMKYEHGTGCWQGPNRSTTVKLTCGKETMLTSTSEPSRCEYLMEFITPAVCQEPSNIDLSAHGHTEL
Protein: Probable apyrase 5 (AtAPY5) (EC 3.6.1.5) (ATP-diphosphatase) (ATP-diphosphohydrolase) (Adenosine diphosphatase) (ADPase) (NTPDase) (Nucleoside triphosphate diphosphohydrolase 5) (Q6NQA8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates.
Subcellular location: Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Apyrase 1
- Apyrase 2
- Adenylosuccinate lyase
- Ribonucleoside-diphosphate reductase small chain A
- Ribonucleoside-diphosphate reductase small chain C
- AICARFT/IMPCHase bienzyme family protein
- Ribonucleoside-diphosphate reductase large subunit
- At1g72880
- UMP-CMP kinase 3
- Probable UMP-CMP kinase 1
Sequence:
MDALKVQILPDNQSSPSSTHMLTKPKSKKATKSIAMLIVASLAITLGLLFVFSSNSVMFSASFLRRSSLHYSVIIDAGSSGTRIHVFGYWFESGKPVFDFGEEHYASLKLSPGLSSYADNPEGASVSVTKLVEFAKGRIPKGKLKKSDIRLMATAGMRLLDVPVQEQILDVTRRVLRSSGFKFQDEWATVISGTDEGIYAWVVANHALGSLGGDPLKTTGIVELGGASAQVTFVPSEHVPPEFSRTISYGNVSYTIYSHSFLDFGQDAAEDKLLESLQNSVAASTGDGIVEDPCTPKGYIYDTHSQKDSSGFLSEESKFKASLQVQAAGDFTKCRSATLAMLQEGKENCAYKHCSIGSTFTPNIQGSFLATENFFHTSKFFGLGEKEWLSEMILAGKRFCGEEWSKLKEKYPTTKDKYLHRYCFSSAYIISMLHDSLGVALDDERIKYASKAGKENIPLDWALGAFILNTDTPTSDYNGKSRKMIGFK
Protein: Natriuretic peptides A (Prepronatriodilatin) [Cleaved into: Atrial natriuretic factor (ANF) (Atrial natriuretic peptide) (ANP)] (P18908)
Organism: Gallus gallus (Chicken)
Function: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity).
Subcellular location: Secreted.
Interaction partners:
- Natriuretic peptide receptor 3.
- Guanylate cyclase.
- Corin, serine peptidase.
- Uncharacterized protein.
- Insulin degrading enzyme
- Interleukin-6 receptor subunit beta
- KIAA2013.
Sequence:
MDTRGSFSCGFLLLLLIQLQPSRANPIYNLSPAKELASMEALLERLEDKFALIEALESNPDLQEPQTQEEIPPELTDDSDEQKAEPKLASNTPLSYRNPFLKRLRGVQMPRMMRDSGCFGRRIDRIGSLSGMGCNGSRKN
Protein: Double homeobox protein 4C (Double homeobox protein 4, centromeric) (DUX4c) (Double homeobox protein 4-like protein 9) (Q6RFH8)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation (By similarity). Down-regulates MYOD1 expression and may up-regulate MYF5 expression. May regulate microRNA (miRNA) transcription, up-regulating the expression of some myogenic miRNAs, including MIR1-1, MIR133A2, MIR133B and MIR206. Impairs the differentiation of myoblasts and may be involved in muscle regeneration.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19829708, ECO:0000269|PubMed:26816005, ECO:0000269|PubMed:36882853}. Cytoplasm {ECO:0000269|PubMed:26816005, ECO:0000269|PubMed:36882853}. Note=Localizes to the nucleus in proliferating muscle cells but is predominantly cytoplasmic in muscle cells following differentiation. {ECO:0000269|PubMed:26816005}.
Interaction partners:
Sequence:
MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASAASTDASHPGASQPLQEPGRSSTVTSSLLYELL
Protein: GrpE protein homolog (Q9XQC7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion matrix {ECO:0000256|RuleBase:RU000640}.
Interaction partners:
- Heat shock 70 kDa protein 4
- Mitochondrial import inner membrane translocase subunit PAM16 like 2
- 20 kDa chaperonin, chloroplastic
- Chaperonin CPN60, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM44-1
- Mitochondrial import inner membrane translocase subunit TIM44-2
- Heat shock protein 90-5, chloroplastic
- Heat shock 70 kDa protein 6, chloroplastic
- 10 kDa chaperonin 2, chloroplastic
- T-complex protein 1 subunit alpha
Sequence:
MAGLLKTPSLHLTPTLLHAPSVPFKPFCVSFAGGRNVSVSLSRRASLRSVSSGYPLRLLNLVPFASGEAETTETEVESNEPEVQETDGAVDVENENASAEEGEAEEEEAAVITALLKSYKEALADNNEGKIAEIEASLKSIEDEKFLLADKVASLSNELSVERDRLIRISADFDNFRKRTERERLNLVSNAQGEVVENLLAVLDNFERAKSQIKVETEGEEKVTNSYQSIYKQFVEILGSLGVIHVETVGKQFDPMLHEAIMREDSAEYEEGIVLEEYRKGFLLGERLLRPSMVKVSAGPGPEKPLEAEGEEATAQGSAEEESSSS