wanglab/gogpt-training-data huggingface dataset:
Protein: Thyroid hormone-inducible hepatic protein (Spot 14 protein) (S14) (SPOT14) (Q62264)
Organism: Mus musculus (Mouse)
Function: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:20952656}. Cytoplasm {ECO:0000269|PubMed:20952656}.
Interaction partners:
- Mid1-interacting protein 1
- Fatty acid synthase
- Very long chain fatty acid elongase 6
- Insulin receptor
- ATP-citrate synthase
- Acetyl-CoA carboxylase 1
- Suppressor of cytokine signaling 3
Sequence:
MQVLTKRYPKNCLLTVMDRYSAVVRNMEQVVMIPSLLRDVQLSGPGGSVQDGAPDLYTYFTMLKSICVEVDHGLLPREEWQAKVAGNETSEAENDAAETEEAEEDRISEELDLEAQFHLHFCSLHHILTHLTRKAQEVTRKYQEMTGQVL
Protein: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (NAD-dependent glyceraldehyde-3-phosphate dehydrogenase) (P52987)
Organism: Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Function: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MVVKVGINGFGRIGRLALRRIQEVEGVEVAHINDLTDPAMLAHLLKYDTTQGRFKGTVEVKEDGFDVNGKFVKVTAERNPEDIQWADSGVEIVLEATGFFATKEKAEKHLHPGGAKKVLITAPGGNDVKTVVFNTNHTILDGTETVISAGSCTTNSLAPMADALNKNFGVKGGTMTTVHSYTGDQMTLDGPHRGGDFRRARAAAENIVPASSGAAKAIGLVLPELSGLMKGHAQRVSTPTGSITELVTVLEKHVTVDEINEAMKAAADESFGYNVDEIVSSDIIGMAYGSLFDATLTEVTDLKDGGQLVKTAAWYDNEMSFTAQLIRTLEYFAKIAK
Protein: PH domain-containing protein (Q382R7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSAVSALTATIGVLRRLLNEEKTDLEQLTYVVQCIHDPILECYNSPNDGKQGQWLFETPNVASILTATEHRDIFGNIFALYNKHKWIVSRLESALREPNRKQENGAEATGQSSSNAKENAEAAALRDVVELFCSNEMQQFITEHLKYSLSYSSTIAPKILGLWHRCCPTHAKNATGKLSLDSGFIRVVDKRGELSFRKRFLCFLWWTLGERSGVPMDPRAVRVRLPDSLSPATAPPASTGQGHPCASPPLKSNAGEGHSNGRPGSVSNAIKMTFSSPSAGWEESLIPPTWQGFETLLALLATPLPSLRRYVHVACCIVNTHCLQRSIRQQLQFNFVTLARQRMAEENCMVLNELIKQDTGHITSLIDGAGAASADKAKAAALLPGYTAKKFARVDPDKDGCRVLIHYGRLTKKFRRGRHERLVFLFNDWFCYGEEHVNNQLLLRASLSLDGLKVVDHSNVEDGDNSFDVVTQKMRFSFIAPTQEQKRQWVDALLNTVRLYEKRLSKPQQPSNSSGGDSKLAVRKTVSVLPTKSVRLTRNSRLVRQQRVDRLVQGQLSMRRAASATQGAVSDEEAVGPVAMQDTLVAPDDVGGLQDIESPLQQEEVEVEKDAADGNVVSDDGEWAEREQVDVAAEVESDDSGDIVGHEGRSSAEGEGEGGPDAHRTLGRCTEELRDESSGNSKEVSGTLQGGEASTSLEDTGGTTPLPKHDSGEPNDSYHRTNEEPGVTQPRELPVERRGGNLGVNKELGTSGHEGRGSEHENDKEQSNGDVKGSDVKRCKTEGRENREEVEERRCESEDEEEEEELCESSEGDNKGKGGEDERRNDEEGGGPTNVGDMEEVERKEVVVEGEEQVEVEEKTEEGCEEAQDLPPPPAYTIECVASSENEASGPPCSADESDDVVNATKEVAKNNDEGIPNGGETVKQESNRSSGCDKICADGSKPTKAAPEEMEKSRTDEAKPQAARAEEKELNE
Protein: Heavy metal-associated isoprenylated plant protein 26 (AtHIP26) (AtHIPP26) (Farnesylated protein 6) (AtFP6) (Q9SZN7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Heavy-metal-binding protein. Binds lead, cadmium and copper. May be involved in heavy-metal transport. May be involved in cadmium transport and play a role in cadmium detoxification.
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:18974936}. Cell membrane {ECO:0000269|PubMed:18823312}. Note=PubMed:18974936 shows that isopernylation may be important for a speckle-like nuclear localization in a heterologous system, while PubMed:18823312 shows a plasma membrane localization. {ECO:0000269|PubMed:18823312, ECO:0000269|PubMed:18974936}.
Interaction partners:
- Zinc-finger homeodomain protein 11
- Acyl-CoA-binding domain-containing protein 2
- Probable magnesium transporter NIPA7
- Probable magnesium transporter NIPA6
- Heavy metal transport/detoxification superfamily protein
- Acyl-CoA-binding domain-containing protein 6
- Acyl-CoA-binding domain-containing protein 1
- Methylsterol monooxygenase 1-2
- Heavy metal-associated isoprenylated plant protein 16
- Heavy metal-associated isoprenylated plant protein 39
Sequence:
MGVLDHVSEMFDCSHGHKIKKRKQLQTVEIKVKMDCEGCERKVRRSVEGMKGVSSVTLEPKAHKVTVVGYVDPNKVVARMSHRTGKKVELWPYVPYDVVAHPYAAGVYDKKAPSGYVRRVDDPGVSQLARASSTEVRYTTAFSDENPAACVVM
Protein: Nitrate/nitrite sensor protein NarX (EC 2.7.13.3) (P0AFA2)
Organism: Escherichia coli (strain K12)
Function: Acts as a sensor for nitrate/nitrite and transduces signal of nitrate availability to the NarL protein and of both nitrate/nitrite to the NarP protein. NarX probably activates NarL and NarP by phosphorylation in the presence of nitrate. NarX also plays a negative role in controlling NarL activity, probably through dephosphorylation in the absence of nitrate.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- Nitrate/nitrite response regulator protein NarL
- Nitrate/nitrite response regulator protein NarP
- Nitrate/nitrite antiporter NarK
- Respiratory nitrate reductase 1 alpha chain
- Sensor histidine kinase DcuS
- Sensor histidine kinase DpiB
- Sensor protein TorS
- Transcriptional regulatory protein UhpA
- Nitrate reductase molybdenum cofactor assembly chaperone NarJ
- Sensor protein PhoQ
Sequence:
MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGLQDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAVFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQNLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRLADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGDCRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE
Protein: Zinc finger protein Gfi-1 (Growth factor independent protein 1) (Zinc finger protein 163) (Q99684)
Organism: Homo sapiens (Human)
Function: Transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5'-TAAATCAC[AT]GCA-3' in the promoter region of a large number of genes. Component of several complexes, including the EHMT2-GFI1-HDAC1, AJUBA-GFI1-HDAC1 and RCOR-GFI-KDM1A-HDAC complexes, that suppress, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Regulates neutrophil differentiation, promotes proliferation of lymphoid cells, and is required for granulocyte development. Inhibits SPI1 transcriptional activity at macrophage-specific genes, repressing macrophage differentiation of myeloid progenitor cells and promoting granulocyte commitment (By similarity). Mediates, together with U2AF1L4, the alternative splicing of CD45 and controls T-cell receptor signaling. Regulates the endotoxin-mediated Toll-like receptor (TLR) inflammatory response by antagonizing RELA. Cooperates with CBFA2T2 to regulate ITGB1-dependent neurite growth. Controls cell-cycle progression by repressing CDKNIA/p21 transcription in response to TGFB1 via recruitment of GFI1 by ZBTB17 to the CDKNIA/p21 and CDKNIB promoters. Required for the maintenance of inner ear hair cells.
Subcellular location: Nucleus {ECO:0000269|PubMed:11060035, ECO:0000269|PubMed:12874834, ECO:0000269|PubMed:18805794, ECO:0000269|PubMed:20547752, ECO:0000269|PubMed:8754800}. Note=Colocalizes with PIAS3 and RUNX1T1 in nuclear dots.
Interaction partners:
- Lysine-specific histone demethylase 1A FAD-dependent demethylase 1A)
- Histone deacetylase 1
- Endothelial transcription factor GATA-2
- Histone-lysine N-methyltransferase EHMT2
- POU domain, class 4, transcription factor 3
- CCAAT/enhancer-binding protein alpha
- Transcription factor PU.1
- REST corepressor 1
- Histone deacetylase 2
- Runt-related transcription factor 1
Sequence:
MPRSFLVKSKKAHSYHQPRSPGPDYSLRLENVPAPSRADSTSNAGGAKAEPRDRLSPESQLTEAPDRASASPDSCEGSVCERSSEFEDFWRPPSPSASPASEKSMCPSLDEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYGPKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGLHADKGAGVKVESELLCTRLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQHGLK
Protein: Inactive L-threonine 3-dehydrogenase, mitochondrial (Short chain dehydrogenase/reductase family 14E member 1 pseudogene) (Q8IZJ6)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q8MIR0}.
Interaction partners:
Sequence:
MLFIRMLRRAGQSPACGCWTPVLPVRFLGISPRQIPADANFHSASFSDTDHPRVLITGALGQLGVGLANLLRKRFGKDSVILSDIRKPPDHVFHSGPFIYSDILDYKNLREIVVNNRITWLFHYSALLSAFGEANVSLARAVNITGLHNILDVAAEHNLQLFVPSTIGAFGPTSPRNPTPDLCIQRPRTIYGVSKVHAELMGETMQSRFSMMPQSMANSSATWKPARDCP
Protein: Stretchin-Mlck, isoform R (EC 2.7.11.17, EC 2.7.11.18) (A1ZA73)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGETENGDIEPRASAEPEAASAQDTLQVPTQKKRKLKSPTPGSLRGRSATPIHGRSQTPFTLYMTRRSATPSTWRSITPFLKREEKEKTPFELGRDIKSQTTCNIAVFDRALVMDISEPLDVQKPVRYITSDLSVIDRAAVMDVSNVEVIYVVEEYEEVEEEEIIEEVKPKKKEKKARKPRAQRKSIDKDMSPSGAEDGDDLGDFGGDDREDSVDLDDGDEPVKKGKKKAPPKKKEKKEKSPSPKLTLKLEIGGGQKASKKMFEQQQQQAKPPPKKSKMVLQMEEQAKAAAKAAEEAAARAKPKGETFEERQKRLQAEKEEQERLEAEQRAQEEAEAEAEAEAEEDEEDPSNVGEEGEEGTEAGYGDEDQEQEYPEDEIEAEPEEDTKKKEKRRGSDSSDDFVRPDPHEEERWQRIAAVEGEEFMQQMRKYSQAKRISEKERDADWQRRREQARNPKFINFLSDRAVEAGQSVRLACAVDGPELSVKWYHNRKQLERDGCHRIINNNNILVLEVLNTTILDSGEYSCVISNQNDETSSSCIVTIYEIFKDEPKPPSIQYIKEYYHLRDDELTIECHVHGYPRPVITWWRGCFQVKPSYKFTMLEEAHGVCKLLIYKPGNKDGGIYTMKAINSSGEVQINHTVEVARNLHYHVPGIFHARDKIQLDSLKQAKKAMEAALKSKADSDQRRAEAEEEQARLHPVKATPERLVPAKQKLAFATQLRDRMALEGSTIKFVATVIGPDPNTRWMKDDKWVVVGGNIKNLSEEGKAILEVGNVTSADSGVYKCVAKNDLSEIETSCYFKVYAAQADGDESEPIFALPLRDVYHASQNDLILDTKVRGNPRPEISWTKDQIPVVLDDRVVQIEHLDGICELIINKPTINDNGIYVCTAKNKLGSQSTTHTVVVDTTHTSRRSSILSAIAMQEGGGGGESADAKAKGKKKKKEDEPEGGDGGYERRSRMPDPSPKQMLYFTVNLSNRYVAEGSKVKLQAVIGGPQPMIKWLKDDQNVTYGPNIRNMNRDSLAVLEFTNAKVEDSGTYSIVAQNESCKITTSAMLHVYETKVNTDVQPVFIRSLKETYHLNTNELILETAVRGQPTPAVQWFKDSIEIQSGGRFQIIEHQDGTCELIIDRPDNKDSGKYVVKAESRAGKMEISHYVLFEGQSHHIAENIHGVFHADKSLLRPKEVEKPVEKKPAPAAEPESEAEDGKAKRRAKKEEDDGASSAYATDYASDTASLSSKRREKNIAIHFSTSMRDRVVAEGSKVKISCFLEAKEPQVKWFKDGEQIQNSPKIRGRYSEGLCLLEVMSATAEDNGEYKCWGRDETGEASTSCRLEVYENPGTGDVPPTFTRNIKDTMHGKINELQLDVHVRGLPTPAVTWVKDGVKIENSDKYQQVDHDDGTCELFISRPKASDSGKYVCQAENREGKTEIVHMITVEPRVRAPRISPPREGRPPRPSGDEEPAAAGEEGAEGAADGEGGEKRRRKPKPDEEEQTSSRREVPPPPDLRKRLYFRNFLSNRTVKSGSNVKWMVNIDGPEPTAKWFFGDQPIAFGPRSKMSMQDGIAWLNLVGVTEEDAGEYTLRVRGSENEIVSTCNLFVYSTGKPEVIPPTFVVGIKDTYSLNENELVLDCRVRGQPRPEIQWIKGTEPIEASEKFKPSDQADGYAKLVIVNPTEKDSGIYWCVARNEGAENKISHQVDFKGRQHYSLEKTHGFFHRDPNKPHFLLPLGNQTVCNGGTVAISAEFMETSTPIEVKWLRDRRVVDGPNVKALADRGVYTLTIMNAGPEVEGTYTCRASNAFGRIESNVNVDVAVGAEKDERPPLFLSRPDTEMKIAVGDPFSLSFRIAGDPKPKLTFMKGTKDITQSDRVSKEVSDDYTRFSVQQAQISDSGTYFVVARNNFGTDRIFVTVTIKIPKKKEE
Protein: G1/S-specific cyclin-E1 (P24864)
Organism: Homo sapiens (Human)
Function: Essential for the control of the cell cycle at the G1/S (start) transition.
Subcellular location: Nucleus {ECO:0000269|PubMed:7739542}.
Interaction partners:
- Cyclin-dependent kinase 4
- Cyclin-dependent kinase 6
- Cyclin-dependent kinase inhibitor 1
- Cyclin-dependent kinase 2
- Cyclin-dependent kinase inhibitor 1B
- F-box/WD repeat-containing protein 7
- Retinoblastoma-associated protein
- M-phase inducer phosphatase 1
- S-phase kinase-associated protein 1
- S-phase kinase-associated protein 2
Sequence:
MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
Protein: Uncharacterized protein (Q386Q2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTSFKDNISSERLLRGAQLASWVVVGGYGVALAYHFGFLRSIFPKSIAASLECAVEKVKSWTEPVGDSVRYAVVRRHLTQVYSIASVGMLAGALGAALFFSFPKVPIAIPVSLTVAPAALLLLLPREVMFPACRVACFLTSSFAVGCSFAPIGWVAWDSLSILMMLTASTMSGLCIPLFLTRGMASYVLSSQLLSCAATIIALTTTPPLLTSTGLNNGGATEVVRVLQRTDVNVLLVMQLMMNWGINLLHTLPTIARFVKWRGSEDELLLTVDPVKEALCICSGGAYVFWRCSQWACRRLVEGTLGAGVGGEAERRGHHATTLYDHLKSTMRSRRVVDAGATVMLVLCYVRAVSTLQKGETVKALETLRVCCARVSPISLVLTRV
Protein: Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma) (P51129)
Organism: Xenopus laevis (African clawed frog)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-cis retinoic acid (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
Sequence:
MHLATETAPSMATYSSTYFNSSLHAHSTSVSSSNLAAMNSLDTHPGYMGNSLNGPRSMTTNMNSMCSPGNNIGLPYRVIASSMGPHSLPSPTILNYPGHESPPFNILNNVSCSEDIKPPPGLSSLGSPCMNNYSCNSPGALTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLVYTCRDSKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRSREKSDTEAESTSSTSEEMPVERILEAELAVDPKIEAFGDAGLPNSTNDPVTNICHAADKQLFTLVEWAKRIPYFSDLPLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHNAGVGSIFDRVLTELVSKMKDMDMDKSELGCLRAIVLFNPDAKGLSNAAEVEALREKVYATLESYTKQKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPHQIS
Protein: Probable E3 ubiquitin-protein ligase TRIML2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIML2) (SPRY domain-containing protein 6) (Tripartite motif family-like protein 2) (Q8N7C3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSKRLSPQLQHNITEDAYCETHLEPTRLFCDVDQITLCSKCFQSQEHKHHMVCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLDTVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTILQHGPSCDATVSP
Protein: Microtubule-associated protein, putative (Q389U9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Telomerase-associated protein, putative
Sequence:
MPGTKGLEADYKWNDPQPYPQRDKERAEVYDCIDIKNKKKSLPHNTENLYMKQQKANKQNYKEILSTMKESYAPIDPAAYKRDMLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDMLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLRKEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEATGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEATGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEATGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEATGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESHAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEVTGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEATGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEEEATGPRHVDPSHFRSTTAESYAPIDPAAYKRDVLREEVVKVSSRGGDDGHFRTTAKDSYCRYDSSCYKSSCRESSFGDESVISKRHSFTASSVADAIVVKKVVKGKSDGGVTSKKVDVSTDMKCVASGESNGGAAAAVAATTECAAAAVGDQPTGNGVRVSKWKKAPNVGYSCPCHVDADMYVSTAHRDFKAHGASKPYMPKAAPTVKQSSISMQGVSSEYRNRFIRPEVQCPPRPIGKPAVQVRHVDPSMYVTTNRATFVNHSGRKV
Protein: Granulocyte colony-stimulating factor (G-CSF) (P09920)
Organism: Mus musculus (Mouse)
Function: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Subcellular location: Secreted.
Interaction partners:
- Granulocyte colony-stimulating factor receptor
- Granulocyte-macrophage colony-stimulating factor
- Eotaxin
- Interleukin-1 beta
- Interferon gamma
- Erythropoietin
- Interleukin-1 alpha
- Tyrosine-protein kinase JAK2
- Thrombopoietin
- Interleukin-6
Sequence:
MAQLSAQRRMKLMALQLLLWQSALWSGREAVPLVTVSALPPSLPLPRSFLLKSLEQVRKIQASGSVLLEQLCATYKLCHPEELVLLGHSLGIPKASLSGCSSQALQQTQCLSQLHSGLCLYQGLLQALSGISPALAPTLDLLQLDVANFATTIWQQMENLGVAPTVQPTQSAMPAFTSAFQRRAGGVLAISYLQGFLETARLALHHLA
Protein: BUB1 mitotic checkpoint serine/threonine kinase (A0A8I6GIT9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}.
Interaction partners:
Sequence:
MPVLFFKQEFTIRLNLWNYYNNNTELHTCFTESSCGYTVCQDLFLEKLFQARLTGTHLPDQATTSEPLHSAQILNQVMLTKSSPETENSACVPRSQGSECSGVAPSTCDEKSNIREQRVIMISKSECSVSSSMAPKPEAQQVMYCKEKLIRGDSEFSFEELRAQKYNQRKKHEQWVSEDRNYMKRKEANAFEEQLLKQKMDELHKKLHQVVELSHKDLPASENRPDANLVCVGQNTCSHQELRGLSLSSINQQTSENSGEKPLEEPSVPLMVNAVNSTLLFPAISLPSLPIPVSGQSETDSRGVNQSIREFMTQSGPDKKEVCETNKVANINDFHTTPNTSLGMVQGTPCKVQPSPTVHTKEALGFIMDMFQAPTLPDISDDKDEWPSLDQNEDAFEAQFQKNAVFSEDWGVKKIMTLSSAFPIFEDGNKENYGLPQPKNKPLGARTFGERSLSKCSSRSNEMPHTDEFMDDSTVCGIRYNKTLAPSPKSIGDFTSAAQLSSTPFHKFPADPLQIPEDKENVVATQYTHMALDSCKENMVDPSKDRKLGLIQEKISASLSCPSQPATGGLLTQEAVFSLETYKCTGTDRAIMEDLSDASAGLQVEWVQTSSFGNVNAPNFTIENPWDDELILKLLSGLSKPVTSYSNTFEWQSKLPAIKTKTEFQLGSLLVYVNHLLGEGAFAQVFEAIHGDTKSKQKCILKVQKPANSWEFYIGMQLMERLKPEVHHMFIKFYSAHLFQNGSILVGELYSYGTLLNVINLYKNTSEKVMPQALVITFAIRMLYMVEQVHSCEIIHGDIKPDNFILGHRFLEQDDEDLATGLTLIDLGQSIDMKLFPKGTVFTGKCETSGFQCPEMLSNKPWNYQVDYYGVAASIYCMLFGTYMKVKNEGGVWKPEGLFRRLPHLDMWEEFFHIMLNIPDCHNLPSLDFLRQKMNKLLEQQYSNKIKTLRNRLIVLLSEYKRSRK
Protein: Protein OBERON 2 (Potyvirus VPg-interacting protein 1) (Q9LUB7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that acts together with OBE1 for the maintenance and/or establishment of both the shoot and root meristems, probably by controlling the expression of the meristem genes such as WUS, PLT1 and PLT2 and of genes required for auxin responses. Promotes cell meristematic activity via the WUSCHEL-CLAVATA pathway. Involved in the development of the basal pole and in auxin-mediated root and vascular development in the embryo. Confers sensitivity to turnip mosaic virus (TuMV) probably by promoting viral movement and multiplication via interaction with TuMV VPg.
Subcellular location: Nucleus {ECO:0000269|PubMed:18403411}.
Interaction partners:
- Cysteine/Histidine-rich C1 domain family protein
- PHD finger protein MALE MEIOCYTE DEATH 1
- Histone acetyltransferase
- Uncharacterized protein At3g24150
- Chromatin remodeling protein SHL
- Protein GOLVEN 10
- Protein SLOW WALKER 2
- PHD finger protein ALFIN-LIKE 5
Sequence:
MGTSSGSNHPHQMLPPRQQQRSGGGLETALSLVSSDQEPRRESPAESASSQETWPLGDTVAGKKSMSQKTEPDSMEQTVNVMHHVSNADKVSVRDIARERVELVAERMHRLPDEFLDELKNGLKSILEGNVAQSVDEFMFLQKVVQSRTDLSSVTLVRAHRVQLEILVAINTGIQAFLHPNISLSQPSLIEIFVYKRCRNIACQNQLPADDCYCDICTNRKGFCNLCMCTICNKFDFSVNTCRWIGCDLCSHWTHTDCAIRDGQITTGSSAKNNTSGPGEIVFKCRACNRTSELLGWVKDVFQHCAPNWDRESLMKELDFVSRIFRGSEDQRGRKLFWKCEELIDKIKGGLAEATAAKLILMFFQEIESDSAKSFENGEGGRLMAPQDACNRIAEVVQETLRKMEIVAEEKMRMFKKARMALETCDRELEDKAKEVSELKAERQKKKLQIDELERIVRLKQAEADMFQLKANEAKREADRLQRIVLAKMDKSEEEYASNYLKQRLSEAEAEKQYLFEKIKLQENSRVASQSSGGGGDPSQVMMYSKIRDLLQGYNLSPKVDPQLNERNPFRSNP
Protein: Lysozyme-like protein 1 (O62415)
Organism: Caenorhabditis elegans
Function: Involved in resistance to Gram-negative bacterium S.marcescens and to bacterium Gram-positive S.aureus infection.
Subcellular location: Cytoplasmic vesicle lumen {ECO:0000269|PubMed:12176330}. Note=Localizes in vesicles in the apical region of intestinal cells. {ECO:0000269|PubMed:12176330}.
Interaction partners:
- C-type LECtin
- C-type lectin domain-containing protein
- Saposin B-type domain-containing protein
- lysozyme
- CUB-like domain-containing protein
- lysozyme
- C-type lectin domain-containing protein
- CUB-like domain-containing protein
- CUB-like domain-containing protein
- Saposin B-type domain-containing protein
Sequence:
MLKLAFVTFLFALASARPQDVDSNRVVALPQDNFEVTDIGFEKIKAEPAPEVVNNDASYAYAVDISVPTTVSQMNCLKTSRYAAVFIRGFTPFGSGAFDTTSVTSIRNAYSAGLGIEVYMTPQPLSSLQGYQQLDALYNGLNGNGITIRSVWIQVTSPANWQKSATTNVNFLNSIISRAKQYGLTVGIYTNQYDWSQITGNWATLSSDVLLWYWHVLGGGVTGETPATFDDFRAFGSFKKASVKQFAQVESVCSLTVNRDVYVVGIPAAASSKNTDFFTQEDISSNNKKIVVGGVIGV
Protein: FI20283p1 (Pcf11 cleavage and polyadenylation factor subunit, isoform B) (E1JH68)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEQLFQNYRDDERRIGEEYLSSLQDLNCNSKPLINMLTMLAEENINYAHIIVKVVEYYISQVAPEFKLPILYLIDSIVKNVKSSYVQLFGQCIVNIFLHAFESVQHSQSQVLEKVRERMYALRQTWNEVFPPSKMYALDVKVKRLDNNWPITAKQPTNKIHVNPAIHVNPDFLKPGLVPGMPGNPTITSDMEEILQAKTRELLELKKRKLELELEQTKKHLEEQERQLTQTTDAMVGAPIIMPAPTPAAICPPITDPGIAVHNQRAPGVMGNVGPVMHNMPVAPQLFANKPKVHPVNPALLNSVRQRDPRLARQMHAASSHPAAPARNDPRLEAKSSSSQKSSRSRSKSPVRNSSSRSGKSGSSSHSSSSSRKRSESKSSTTSSSSSSSDVRHKGVTASSSNQPTVKRSGKITSKDSDRYVRNGSPLGSAKRKSSSPSSSPSKSKRSTSHKSSSSRGKTSSLRSRSRSPVFMDVDLRTGVRSKSPESRAVAPSSLPLAGASLPASAKAPKDLEKRKKQLLILISHLLANNQVWFDLEPRATDSLVENLEYINQNGGTRWLRLVEGRVIGTVCG
Protein: Krueppel-like factor 14 (Basic transcription element-binding protein 5) (BTE-binding protein 5) (Transcription factor BTEB5) (Q8TD94)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MSAAVACLDYFAAECLVSMSAGAVVHRRPPDPEGAGGAAGSEVGAAPPESALPGPGPPGPASVPQLPQVPAPSPGAGGAAPHLLAASVWADLRGSSGEGSWENSGEAPRASSGFSDPIPCSVQTPCSELAPASGAAAVCAPESSSDAPAVPSAPAAPGAPAASGGFSGGALGAGPAPAADQAPRRRSVTPAAKRHQCPFPGCTKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEKRFSCPLCPKQFSRSDHLTKHARRHPTYHPDMIEYRGRRRTPRIDPPLTSEVESSASGSGPGPAPSFTTCL