wanglab/gogpt-training-data huggingface dataset:
Protein: UPF0749 protein Rv1823 (P9WFG1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein Rv1824
- UPF0749 protein Rv1825
- Uncharacterized protein Rv1829
- Putative cardiolipin synthase
- Probable phosphatidylglycerophosphate synthase
- DUF3097 domain-containing protein
- Possible methyltransferase
- Glycine cleavage system H protein
- Protein translocase subunit SecA 2
- RNA pseudouridylate synthase
Sequence:
MAESDRLLGGYDPNAGYSAHAGAQPQRIPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWMWQALAATLVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSAKVDDVRRIVLADDAEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGASPNLSDVSKQRVSGSQQIILDRDLQLVVNSLWESGAEAISIDGVRIGPNVTIRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSYGVGVSVNVGDGLALPAGATRDVKFAKQIGP
Protein: Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (Vesicular-fusion protein NSF) (Q9M0Y8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity). Required for maintaining the normal morphology of the Golgi apparatus.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P54351}.
Interaction partners:
- Alpha-soluble NSF attachment protein 2
- Gamma-soluble NSF attachment protein
- Alpha-soluble NSF attachment protein 1
- SEC1 family transport protein SLY1
- Sec1/munc18-like
- Syntaxin-31
- At3g24315
- Putative syntaxin-24
- Centromere/kinetochore protein zw10 homolog
- Syntaxin-22
Sequence:
MAGRYGSQVMTMTVTNTPSADLAFTNLAYCSSSDLRQFSVPGSDLFLANVADSFILSLCGHGSIRDGNIALNAIQRRHARVSTGDMVSVSRFVPPENFDLAMLTLELEFVKKGTKSEQVDAALLSTQLKRKYTNQVLTVGQKATFEYHGTNYILTVNRADVEGQDHTNGIERGLLSKDTYIVFEASNASGIKIVNQREAASSNIFKHKEFNLESLGIGGLGAEFADIFRRAFASRVFPPHVTSRLGIKHVKGMLLFGPPGTGKTLMARQIGKMLNGKDPKIVNGPEVLSKFVGETEKNVRDLFADAEQDQRTLGDASELHVIIFDEIDAICKSRGSTRDGTGVHDSIVNQLLTKIDGVEALNNVLLIGMTNRKDLLDEALLRPGRLEVQVEISLPDEAGRLQILQIHTNKMKENSFLGTDINLQELAARTKNYSGAELEGVVKSATSYALNRQLSMDDLTKPVEEENIKITMEDFLHAIYEVQPAFGASTDDLERCRLNGMVDCGHRHNHIYKRAMLLVEQVKVSTRSPLVTCLLEGPSGSGKTALAATIGIDSDFPYVKIVSAETMIGLSESTKCAHIVKVFEDAYKSPMSIIILDDIERLLEFIAIGPRFSNIISQTLMVLLKRLPPKGKKLLVFGTTSEVTFLESVGISDCFSVTHSVPTLQKEDAKKVLNQLNLFSEDDVDSAAEALNDMPIKKIYMLIEMAAQGENGGSAEAIYAGREKININHFYDCLGDFIRFTG
Protein: RNA polymerase sigma-H factor (Sigma-30) (Q06198)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis.
Interaction partners:
- Sigma factor AlgU negative regulatory protein
- Sigma factor AlgU regulatory protein MucB
- Positive regulator for alginate biosynthesis MucC
- Positive alginate biosynthesis regulatory protein
- Probable periplasmic serine endoprotease DegP-like
- RNA polymerase sigma-54 factor
- Alginate biosynthesis transcriptional regulatory protein AlgB
- Alginate biosynthesis protein AlgZ/FimS
- AlgW protein
- Transcription factor AmrZ
Sequence:
MLTQEQDQQLVERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDAQEAQDVAQEAFIKAYRALGNFRGDSAFYTWLYRIAINTAKNHLVARGRRPPDSDVTAEDAEFFEGDHALKDIESPERAMLRDEIEATVHQTIQQLPEDLRTALTLREFEGLSYEDIATVMQCPVGTVRSRIFRAREAIDKALQPLLREA
Protein: Synaptobrevin homologue SNC1/2 (Eurofung) (Q5ASG1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Vesicle transport v-SNARE protein vti1
- Protein transport protein SEC9
- Uncharacterized protein
- Vesicular-fusion protein sec17
- SNARE complex subunit
- ER-Golgi SNARE complex subunit Sed5
- Sec1 family superfamily
- SNARE complex subunit
- t-SNARE coiled-coil homology domain-containing protein
- Golgi SNAP receptor complex member 1
Sequence:
MSEQPYDPYIPSGSNAASGSTAQNGDNRTREIDRKIQETVDTMRSNIFKVSERGERLDSLQDKTDNLAVSAQGFRRGANRVRKQMWWKDMKMRVCLIICIILLLVVIIVPAVVTTTR
Protein: NHL-repeat-containing protein 4 (P0CG21)
Organism: Homo sapiens (Human)
Interaction partners:
- Proline-rich protein 35
Sequence:
MLGLEGPCWVGPGPDGGLAVSEEFGDVRLFGSARQPLGSLGGWTGHTFGCPAGICSNSEGNVIVADEQRRQVTLFPRAGPPICLVSEGLGQPLGVACAPQGQLLVADAKDNSIKVYQGLKELA
Protein: Small ribosomal subunit protein uS3c (30S ribosomal protein S3, chloroplastic) (P0C483)
Organism: Oryza sativa (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
Sequence:
MGQKINPLGFRLGTTQNHHSFWFAQPKNYSEGLQEDKKIRNCIKNYIQKNRKKGSNRKIEADSSFEVITHNKKMDSGSSSEVITHIEIQKEIDTIHVIIHIGFPNLLKKKGAIEELEKDLQKEVNSVNQRLNIGIEKVKEPYRQPNILAEYIAFQLKNRVSFRKAMKKAIELTKKTDIKGVKVKIAGRLAGKEIARAECIKKGRLPLQTIRAKIDYCCYPIRTIYGVLGVKIWIFVDEE
Protein: dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) (Q9SLN0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
- Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Dolichol-phosphate mannose synthase subunit 2
- Dol-P-Man:Man
- Alpha-1,2-mannosyltransferase ALG9
- Dol-P-Glc:Glc
- Dol-P-Man:Man
- Dolichol-phosphate mannose synthase subunit 3
- Dolichol-phosphate mannosyltransferase subunit 1
- At3g57220
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Sequence:
MEFLVTVAEFSLWLLLIVLFGFLSVVVFEAWRRRHSNVSVETVTTLDDPKSIKPIPCPHITDPAEKYLSLIVPAYNEELRLPAALEETMDYLQDRASRDKSFSFEVVIVDDGSVDGTKRVAFDFIRKYTIDNIRVIPLGKNQGKGEAIRKGMLHSRGQLLLMLDADGATKVTDLEKLENQINAVAREEYSIRNPASKDMDFKIGDVQVSAFGSRAHLEEKALATRKWYRNFLMKGFHLVVLLAAGPGIRDTQCGFKMFTRAAARRLFTNVHLKRWCFDVELVYLCKRFNIPMVEISVKWSEIPGSKVSMLSIPNMLWELALMSVGYRTGMWKIHQV
Protein: Triosephosphate isomerase, chloroplastic (TIM) (Triose-phosphate isomerase) (EC 5.3.1.1) (Q9SKP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000250}.
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPCP1, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPCP2, chloroplastic
- Phosphoglycerate kinase 3, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic
- Phosphoglycerate kinase 1, chloroplastic
- Phosphoglycerate kinase 2, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPB, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPA2, chloroplastic
Sequence:
MAATSLTAPPSFSGLRRISPKLDAAAVSSHQSFFHRVNSSTRLVSSSSSSHRSPRGVVAMAGSGKFFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTDRIDISGQNSWVGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACIGEKLEEREAGKTFDVCFAQLKAFADAVPSWDNIVVAYEPVWAIGTGKVASPQQAQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPEFATIVNSVTSKKVAA
Protein: Olfactory receptor 2J2 (Hs6M1-6) (Olfactory receptor 6-8) (OR6-8) (Olfactory receptor OR6-19) (O76002)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MMIKKNASSEDFFILLGFSNWPQLEVVLFVVILIFYLMTLTGNLFIIILSYVDSHLHTPMYFFLSNLSFLDLCHTTSSIPQLLVNLRGPEKTISYAGCMVQLYFVLALGIAECVLLVVMSYDRYVAVCRPLHYTVLMHPRFCHLLAAASWVIGFTISALHSSFTFWVPLCGHRLVDHFFCEVPALLRLSCVDTHANELTLMVMSSIFVLIPLILILTAYGAIARAVLSMQSTTGLQKVFRTCGAHLMVVSLFFIPVMCMYLQPPSENSPDQGKFIALFYTVVTPSLNPLIYTLRNKHVKGAAKRLLGWEWGK
Protein: Fibroblast growth factor (FGF) (Q76LI5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Fibroblast growth factor receptor
- Fibroblast growth factor receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 4
- Klotho
- Pro-epidermal growth factor
- Vascular endothelial growth factor receptor 2
- Fibroblast growth factor 23
- Vascular endothelial growth factor receptor 3
- Platelet-derived growth factor receptor alpha
Sequence:
MGSPRSALSCLLLHLLVLCLQAQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Protein: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3) (Q922H2)
Organism: Mus musculus (Mouse)
Function: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Dihydrolipoyl dehydrogenase, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- Pyruvate dehydrogenase protein X component, mitochondrial
- [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
Sequence:
MRLFYRLLKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPRVLDNFLNVLINIRNRHNDVVPTMAQGVIEYKEKFGFDPFISSNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPAHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELHEDKKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQDKIKSNRTF
Protein: Organic solute transporter subunit alpha (OST-alpha) (Solute carrier family 51 subunit alpha) (Q8R000)
Organism: Mus musculus (Mouse)
Function: Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids (taurocholate). Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids. Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (By similarity). Able to transport eicosanoids such as prostaglandin E2 (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Mainly restricted to the lateral and basal membranes of ileal enterocytes. Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B. {ECO:0000269|PubMed:17650074}.
Interaction partners:
- Organic solute transporter subunit beta
- Ileal sodium/bile acid cotransporter
- Bile salt export pump
- Bile acid receptor
- Hepatic sodium/bile acid cotransporter
- Cytochrome P450 7A1
- Fibroblast growth factor 15
- Nuclear receptor subfamily 0 group B member 2
- Gastrotropin
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
Sequence:
MEPGRTHIKLDPRYTAELLELLETNYSISPACFSHPPTAAQLLRALGPVDIALTIILTFLTTGSVAIFLEDAVYLYKNTLCPIKKRTLIWSSSAPTVVSVFCCFGLWIPRALTLVEMAITSFYAVCFYLLMMVMVEGFGGKKAVLRTLKDTPMRVHTGPCCCCCPCCPPLILTRKKLQLLLLGPFQYAFFKITLSIVGLFLIPDGIYDPGEISEKSAALWINNLLAVSTLLALWSLAILFRQAKMHLGEQNMGSKFALFQVLVILTALQPAIFSILANSGQIACSPPYSSKIRSQVMNCHMLILETFLMTVLTRMYYRRKDDKVGYEACSLPDLDSALKA
Protein: Ceramide kinase-like isoform 29 (G0XYH7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAMPCPCSMAPRGFTPDTRLHNGSMALRVVRNTTRSEFVKHLKRHSSVKNQFNFPFVETYIIEEVKIHPKSNSNGYSPQEEGGNHTTASEHGFPWNVDGDLMEAASEVHIRLHPRLIRLYGGSLEEMNDCKVACDCI
Protein: Flavo-diiron protein FprA1 (FDP 1) (Flavoprotein A1) (H(2)O-forming NADH oxidase) (EC 1.6.3.4) (NADH oxidase) (NADH:O(2) oxidoreductase) (Q97K92)
Organism: Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)
Function: Catalyzes the four-electron reduction of molecular oxygen to water. In fact, functions as the terminal component of an NADH oxidase (NADH:O(2) oxidoreductase) when using NADH:rubredoxin oxidoreductase (NROR) and rubredoxin (Rd) as electron transport intermediaries between NADH and FDP. Is thus able to reductively scavenge intracellular dioxygen and is part of an oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.
Interaction partners:
- NADH-rubredoxin oxidoreductase
- Desulfoferrodoxin
- Rubredoxin
- Reverse rubrerythrin-2
- Reverse rubrerythrin-1
- Transcriptional regulator PerR
Sequence:
MSAEKLCENVYWVGVKDQKLRVFDIIMNTKKGSTYNSYLINDDKVAIIDTVKDGFYDEFLKSIKSVIGDKKVDYIVVQHTELDHSGSMYRLIKEYPEAKVVSSKAANMYLKEIVNDEFNSLDAMEVKELNLGKNTLEFISAPNLHWPDTMFTYNKENNILFTCDVMGCHYCPDGSIKDEGGEDYLPEMRYYFDVIMSPFKKFVNMGLDKIKDLKLDMIAPSHGPVHINDIEESVKLYREWAKEKEPKEKNVQIFYITAYGNTGIMAKHLCEDINKKGVKAEVHEITDMKMEDIVELIADANGVLVGSPTINQDAVRPVWDVLSSVCPIVNRGKAAAAFGSYGWSGEGVPMMMDRLKSLKFKTPDNGLKFKFVPASKEFSEADKFVDDFIGLL
Protein: Putative uncharacterized protein DDB_G0279653 (Q54WH7)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSSNNNFDNNKNNNNNNNSNQNNNNIDNGGNNNETNPTTWKFKAQTPTDFNITVRKRRNSEPGVLVQRSYKNYVTHWKLETKKPTKYKDAKEERLRQQAQQQQQAQQQAQQQQQQAQQQQQQQQQQQQQQQQQQQAQQQAQQQQNQHQQNQHQQNQHQQHQQNQNQNQNQNQNQNQNQNQNQNQNQNQNQNQNQNQNQSQNQHLHQLNQHHPIQHQHHSNNHSNNHSNNHPNQQQNHQQNHQQNQYSQQNYQQQNQGQNNYNNNSFQGNSNNNYNNGYNNNSNNSNNNNNNNNNNNNNNNNNNNNNNNNNNKNSISPTSSPLLFPSPSSAFTSIKSTPPKSISGSSSPFQDQARSPSSSFFHDRDLPFSRGGAQRKPSIGDEFKFHPYSLNNKVTNLIDNCNNSNNNNNNNCTESNDDDSPLNGGLGYSRLSQRRISLPILANRPPSPERSLSPIHERNSLNIINGFNKNNNNNNNNNNNNNNSNNNNNNNGNNNPLPHINFENRRPSREEPIVIINNNNDNNYNKIPSQHMHDKKSSPTPRSILKQTISKYHGNECEEEEEYNTNSNYYGDNDNRNISNQNLVASNASQSSGSKLPSIQSLLNDVSISDNKSKSNSNSPTIIGMNNNFVGGANENISKLSSITMNHHSNFNNLVDDNSHISNNNYNNHHNNNNNNNNNTNNNNHNNNINNNNNNNNNSNNNSNNNNNNSNNNNNNNNNSSNNNNNNNNNNNNNSNNNNNNNNDNNNRSPRNMLFYLNK
Protein: Apoptosis inhibitory protein 5 (API5) (At2g34040) (Expressed protein) (O22957)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Homeobox-leucine zipper protein HAT7
Sequence:
MSENQSEEVQQIEKLYEFSERLNASKDKSQNVEDYEGIIKMSKTSMKAKQLASQLIPRYFKFFPSLSTEAFDAHMDCIDDGDLGVRVQAIRGLPLFCKDTPDILSKIVDVLVQLLNTEEPVERDAVHKALMSLLRQDPKASSTALFTHAGVTPTTDDQIREKVLNFIRDKVIPLKGELLKPQEEMERHITDLIKQSLEDVTGGEFKMFMDFLTSLSIFGGKAPPERMQELVEIIEGQADLNAQFEFSDTDHIDRLISCLQLALPFFARGAPSSRFLIYLNKHIIPVFDKLPEERKLDLLKALADISPYTTAQEARQLLPSIVELLKIYMPARKTGEEMNFTYVECLLYAFHHLAHKVPNATNSLCGYKIVTGQPSDRLGEDFSELNKDFTERLTIVEDLTKATMKKLTQGMTEHNKAMSAAKTDEEKASIKTKRQNTTTGLRTCNNILAMTKPLHAKVPPFIGDTNLNLSWKEATKPLASTTTTIGGKRPANSNNGSGNNVAAKKGRGSGTMQNQLVNKAFEGISSYGAGRGGNRGWGRRGGGRGRGQGRGHW
Protein: Protein TRS1 (Q6SVX2)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Inhibits the establishment of the antiviral state in the infected cell. Prevents the phosphorylation of the host eukaryotic translation initiation factor eIF-2alpha/EIF2S1 and thus the shutoff of viral and cellular protein synthesis by directly interacting with EIF2AK2/PKR. Also inhibits host autophagy by interacting with host Beclin-1/BECN1 (By similarity).
Subcellular location: Virion {ECO:0000250|UniProtKB:P09695}. Host cytoplasm {ECO:0000250|UniProtKB:P09695}. Host nucleus {ECO:0000250|UniProtKB:P09695}.
Interaction partners:
Sequence:
MAQRNGMSPRPPPLGRGRGAGGPSGVGSSPPSSCVPMGATSTAGTGASAAPTATPGHGVHRVEPRGPPGAPPSSGNNSNFWHGPERLLLSQIPVERQALTELEYQAMGAVWRAAFLANSTGRAMRKWSQRDAGTLLPLGRPYGFYARVTPRSQMNGVGATDLRQLSPRDAWIVLVATVVHEVDPAADPTVGDKAGHPEGLCAQDGLYLALGAGFRVFVYDLANNTLILAARDADEWFRHGAGEVVRLYRCNRLGVGTPRATLLPQPALRQTLLRAEEATALGRELRRRWAGTTVALQTPGRRLQPMVLLGAWQELAQYEPFASAPHPASLLTAVRRHLNQRLCCGWLALGAVLPARWLGCAAGPATGTTSPPAASGTETEAAGGDAPCAMAGAVGSAVTIPPQPYGGAGGSAICVPNADAHAVVGADATAAAAAAAAAPTVMVGPTAMAGPAASGTVPRAMLVVVLDELGAVFGYCPLDGHVYPLAAELSHFLRAGVLGALALGRESAPAAEAARRLLPELDREQWERPRWDALHLHPRAALWAREPHGQLAFLLRPGRGEAEVLTLATKHPVICANVEDYLQDARRRADAQALGLDLATVVMEAGGQMIHKKTKKPKGKEDESVMKGKHSRYTRPTEPPLTPQASLGRALRRDDEDWKPSRVPGEDSWYDLDETFWVLGSNRKNDVYQRRWKKTVLRCGLEIDRPMPTVPKGCRPQTFTHEGIQLMGGATQEPLDTGLYAPSHVTSAFVPSVYMPPTVPYPDPAARLCRDMRRVTFSNVATHYHYNA
Protein: Putative transporter SVOPL (SV2-related protein-like) (SVOP-like protein) (Q8N434)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Major facilitator superfamily domain-containing protein 9
Sequence:
MATKPTEPVTILSLRKLSLGTAEPQVKEPKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWRWLIRVASIPGIILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQIK
Protein: Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60) (Q8IY21)
Organism: Homo sapiens (Human)
Function: Positively regulates RIGI- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of RIGI to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21791617}.
Interaction partners:
- Antiviral innate immune response receptor RIG-I
- Interferon-induced helicase C domain-containing protein 1
- Antiviral innate immune response effector IFIT1
- Ubiquitin-like protein ISG15
- Interferon-induced protein with tetratricopeptide repeats 3
- 2'-5'-oligoadenylate synthase 1
- Ubiquitin-like protein FUBI
- Interferon-induced protein 44
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- 2'-5'-oligoadenylate synthase 2
Sequence:
MERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRSQAPVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSISVSLRELCENEDDNVVLAFEQLSTTFWEKLNKV
Protein: Xyloglucan endotransglucosylase/hydrolase protein 24 (At-XTH24) (XTH-24) (EC 2.4.1.207) (Endo-xyloglucan transferase) (Meristem protein 5) (MERI-5 protein) (MERI5 protein) (Xyloglucan endo-1,4-beta-D-glucanase) (P24806)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. May be required during development to modify the walls of cells under mechanical stress.
Subcellular location: Secreted, cell wall {ECO:0000305}. Secreted, extracellular space, apoplast {ECO:0000305}.
Interaction partners:
- Senescence-specific cysteine protease SAG12
- Beta-D-xylosidase 1
Sequence:
MSPFKIFFFTTLLVAAFSVSAADFNTDVNVAWGNGRGKILNNGQLLTLSLDKSSGSGFQSKTEYLFGKIDMQIKLVPGNSAGTVTTFYLKSEGSTWDEIDFEFLGNMSGDPYTLHTNVYTQGKGDKEQQFHLWFDPTANFHTYSILWNPQRIILTVDDTPIREFKNYESLGVLFPKNKPMRMYASLWNADDWATRGGLVKTDWSKAPFMASYRNIKIDSKPNSNWYTQEMDSTSQARLKWVQKNYMIYNYCTDHRRFPQGAPKECTTSS
Protein: Tyrosine ammonia-lyase (EC 4.3.1.23) (Q3IWB0)
Organism: Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides)
Function: Catalyzes the non-oxidative deamination of L-tyrosine. Has very low phenylalanine ammonia-lyase activity (in vitro).
Interaction partners:
- Urocanate hydratase
- Imidazolonepropionase
- Histidinol-phosphate aminotransferase
- histidinol-phosphate transaminase
- Aminotransferase
- aspartate transaminase
- Aromatic amino acid aminotransferase apoenzyme
- Formiminoglutamate deiminase
- enoyl-CoA hydratase
- 3-hydroxyacyl-CoA dehydrogenase
Sequence:
MLAMSPPKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGASGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
Protein: Chemotaxis protein CheA (EC 2.7.13.3) (Q52880)
Organism: Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MDMNEIKEIFFQECEEQLAELESGLLKLNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVSFAHVFETTLDCVRSNRLEPNQDVLKVMLRSADVLADLTNAARDGGGVDEARSRQLIKELEALANGELPQAAAESAPKTTPAGVAPAAPVVNEEGFQPVAFSFDDFETGDEPTIEPSTYEIVFKPKSDLYSKGNDATLLLRDLSRLGEMSIHCNMDTLPPLDRMNPEEAYFSWKISLKTDKGEEAIRSVFEFAEWDCELDVALAGGTVGMDEDLPMQPVPFDLSILEDEAQAPAGEEDRAAASEGDSRNAAVAAAQTASNVLQMAQSTARVSPENARNSQSASAAQAAAQQAASAATPTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDTNGTSSINMGLEELQQLTREIQDSVMAIRAQPVKPVFQRMSRIVREIADMTGKSVRLITEGENTEVDKTVIDKLAEPLTHMIRNAVDHGLETPEKRVAAGKNPEGTVRLTAKHRSGRIVIELADDGAGINREKVRQKAIDNDLIAADANLSDEEVDNLIFHAGFSTADKISDISGRGVGMDVVKRSIQALGGRINISSKPGQGSIFTMSLPLTLAVLDGMVVTVANQTLVVPLTAIVETLQPEASAIHSFGSSQRLISIRDSFCPLVDVGRILNFRGAQANPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTHVPGIAAATILGDGRVALILDVDAIVAASRGQSLKPEMSLAAAG
Protein: S-adenosyl-L-methionine:benzoic acid/salicylic acid carboxyl methyltransferase 1 (PhBSMT1) (EC 2.1.1.273) (EC 2.1.1.274) (Q84UB5)
Organism: Petunia hybrida (Petunia)
Function: Converts benzoic acid into the volatile ester methyl benzoates. This scent, mostly produced in a rhythmical, diurnal manner, attracts the pollinators.
Interaction partners:
Sequence:
MEVVEVLHMNGGNGDSSYANNSLVQQKVILMTKPITEQAMIDLYSSLFPETLCIADLGCSLGANTFLVVSQLVKIVEKERKKHGFKSPEFYFHFNDLPGNDFNTLFQSLGAFQEDLRKHIGESFGPCFFSGVPGSFYTRLFPSKSLHFVYSSYSLMWLSQVPNGIENNKGNIYMARTSPLSVIKAYYKQYEIDFSNFLKYRSEELMKGGKMVLTLLGRESEDPTSKECCYIWELLAMALNKLVEEGLIKEEKVDAFNIPQYTPSPAEVKYIVEKEGSFTINRLETSRVHWNASNNEKNGGYNVSRCMRAVAEPLLVSHFDKELMDLVFHKYEEIVSDCMSKENTEFINVIISLTKIN