wanglab/gogpt-training-data huggingface dataset:
Protein: Heterogeneous nuclear ribonucleoprotein L (hnRNP L) (Q8R081)
Organism: Mus musculus (Mouse)
Function: Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPK and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:P14866, ECO:0000305|PubMed:36537238}. Cytoplasm {ECO:0000250|UniProtKB:P14866}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules. {ECO:0000250|UniProtKB:P14866}.
Interaction partners:
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Polypyrimidine tract-binding protein 1
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoproteins C1/C2
- Poly
- Heterogeneous nuclear ribonucleoprotein H
- Heterogeneous nuclear ribonucleoprotein Q
- Heterogeneous nuclear ribonucleoprotein Q
Sequence:
MSRRLLPRAEKRRRRLEQRQQPDEQLRRAGAMVKMAAAGGGGGGGRYYGGGNEGGRAPKRLKTENAGDQHGGGGGGGSGAAGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPDYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
Protein: Signal transducer and activator of transcription (Q6GU23)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
Sequence:
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPFIDAVWK
Protein: Chondrolectin (A0A0C4DFS2)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAYFHELSSRVSFQEARLACESEGGVLLSLENEAEQKLIESMLQNLTKPGTGISDGDFWIGLWRNGDGQTSGACPDLYQWSDGSNSQYRNWYTDEPSCGSEKCVVMYHQPTANPGLGGPYLYQWNDDRCNMKHNYICKYEPEINPTAPVEKPYLTNQPGDTHQNVVVTEAVKEEQKLVQTSLHCGFQRVPEKKVAWKYNNSLTWFQNFVILDLYKEWHQNNSLEWLEITKDLQDEL
Protein: Regulatory protein AsnC (P0ACI6)
Organism: Escherichia coli (strain K12)
Function: Activator of asnA transcription; autogenous regulator of its own transcription; and repressor of the expression of gidA at a post-transcriptional level.
Interaction partners:
- Multiple antibiotic resistance protein MarR
- DNA-binding transcriptional activator DecR
- Aspartate--ammonia ligase
- Protein MioC
- HTH-type transcriptional regulator GntR
- Arsenical resistance operon repressor
- 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
Sequence:
MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP
Protein: Putative outer membrane ligand binding protein BipA (Q9APE8)
Organism: Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Interaction partners:
Sequence:
MNKNIYRVVWSLVRGAWVVAGEWARAGRKSSSPRRQNRQRARRGVAAMVGGSILAQALLPLSALAQGAPTLRPARVAQEEAGQDAAWTRKLAAQAESLARRQAERQPGARVDGDYLKREAQAQVNDVLRDGVNLARESGLPFLRNLQGGLSHDFESGRTSLQLNTIDEVYRAGRNTGLLQLGAHNQNDRPTANAGAVYRREVNDALMVGANGFLDYEFGKQHLRGSVGLEVIAPEFSLYGNVYAPLSDWKGAKRNNRREEKPASGMDVGVGYRPAFAPGLSLSATHFRWNGAEVDYFDNGRTQAGAKGFKVGVEYRPVSLVSVGLEQTKVIGGGRETRMQLGLNINLSEPLSKQLRRDASGTPAFSPDARRHALVERENRIVLNTRRKEIILPLVVSEVSTLQADGRVTVIGATQPFATVTVRMPDGTTGTATADASGRFAYTSAGDQPSGVLALRARNAEGDSSREVTYRYVDEVVLGDLQVAVMALVPLPADRALEVRGKTEPKIDVKVSFPNGESVLAKADAKGLFTVRSTRKVAQGKVLVQATHPQTRKEARAVADYLPPATLAPTIDAVTAQADTGRVTVTGQAEPGAQVDVHFPDGTAKTVDAGADGAYAATSDGDMVSGDIRVQAVDKAGGKSPETIRAYVDTVDKTAPVVPTIADVATDAKSGHITVTGMTEPGAEVVVSFPDGTRKTVVAGDDGAYTATSDGDMVAGDIRVQAIDKAGGKSPEATRHYDDAVDITPPAAPTIANVATDAASGRVTVAGVAEPGANVAVNFPDGTRKTVVAGGDGAYTATSDRDMVSGDIRVQAVDKAGNQSPETTRAYADAVDKTAPEVPTIANVTTDAKSGRITVTGMAEPGVNVAVDFPDGTRKSVVADGAGAYTATSDRDMVSGDIHAQATDKAGNQSPEATRHYGDTTDITPPAAPTIDNVATDATSGRVTAAGVAEPGANVTVNFPDGTRKTVVAGGDGAYTATSDRDMVSGDIRVQATDKAGNQSPEATRAYADAVDRTAPEVPTVTHVATDAKSGRITVTGMAEPGANVTVNFPDGTRKTVVAGGDGAYAATSDRDMVSGDIRVQATDKAGNRSPEATRAYADTVDTTPPAVPTITDVTTDASNGRITVTGVAESGANVTVDFPDGTRKTVVAGGDGAYTATSDRDMVSGDVRVQAIDKGGNHSPEATRAYADAVDKTAPEVPTITNVTTDAASGRITVTGMAEPGANVAVNFPDGTRKTVVADGAGAYAADSDGDMVAGDIHVQATDKAGNRSPEGTRAYVDTVDKTPSAAPTIARVTTDRSSGVVTVAGTADPDNDVTVHFPDGGRKTVKAGKDGSYSVTSDNDIFSGIIQVSARNPAGNASPEVRQDYRDEFVPANAITNMETNSRNGIVTVSGKTSPDATVVVSFPGGDEARTRAKGDGTFSVSSPMDVPRGVVSLSTEVDGVRTVVATRTYEDKFTKGGQDYNAILPYTPGFNGVSTSDTSAVLLSVPQYFYSGGAPVAKIMPPDAHDSEFTKRAAAAMRVQVTSRRNSSEYDIRVSWPAGTFTPADVGQQADLVVKIFDVGTGKFMLAPGEVRFRR
Protein: Adenine phosphoribosyltransferase 2 (APRT 2) (AtAPT2) (EC 2.4.2.7) (Q42563)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. May contribute to the recycling of adenine into adenylate nucleotides and the inactivation of cytokinins by phosphoribosylation. Possesses low activity toward adenine and cytokinins.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:12010467}.
Interaction partners:
- Adenosine kinase 1
- GMP synthase
- AMP deaminase
- Adenosine kinase 2
- Guanylate kinase 3, chloroplastic
- Guanylate kinase 1
- Guanylate kinase 2
- Inosine triphosphate pyrophosphatase
- Adenylosuccinate lyase
- Adenylosuccinate lyase
Sequence:
MFAVENGLQGDPRLKAISDAIRVIPHFPKTGIMFQDITTLLLDPVAFKHVVDIFVDRYKHMNISLVAGVEARGFIFGPPIALAIGAKFVPLRKPGKLPGRVISEEYELEYGRDCLEMSVEAVKSEERALIIDDLVATGGTLSASINLLERAGAEVVECACVVGLPKFKGQCKLKGKPLYVLVEPNQFDELTL
Protein: Heat shock cognate 70 kDa protein (C1BEL8)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRKFDDSVVQADMKHWPFTVINDSTRPKVQVEYKGETKAFYPEEISSMVLVVPHLEQVDPLDQQLRKSTKPFSIILLLIGYYSGPH
Protein: Protein brain tumor (Q8MQJ9)
Organism: Drosophila melanogaster (Fruit fly)
Function: A NHL-domain family protein that functions a translational repressor to inhibit cell proliferation. Plays a central role in translation repression of hb mRNA by being recruited by nos and pum to the Nanos Response Element (NRE), a 16 bp sequence in the hb mRNA 3'-UTR. Probably recruited by other proteins to repress translation of other mRNAs in other tissues. Involved in the regulation of ribosomal RNA synthesis and cell growth. Participates in abdominal segmentation and imaginal disk development. During neuroblast division, segregates asymmetrically and inhibits self-renewal of one of the two daughter cells. Together with the asymmetrically segregating transcription factor prospero ensures that the daughter cell will stop growing, exit the cell cycle, and differentiate into neurons possibly by modulating the function of dm in ganglion mother cells (GMC). Restricts developmental potential of type II intermediary neuronal progenitor (INP) cells playing a role in proliferation and maturation of the neuroblasts.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11274060, ECO:0000269|PubMed:16564014}. Cytoplasm, cell cortex {ECO:0000269|PubMed:16564014, ECO:0000269|PubMed:18342578}. Note=In embryonic and larval neuroblasts, colocalizes with mira throughout mitosis using it as an adapter to segregate into one of the two daughter cells during asymmetric cell division. Accumulates at the apical cell cortex in prophase, forms a basal crescent in metaphase, and segregates into the ganglion mother cell (GMC). It is cortical in telophase but becomes cytoplasmic in interphase after mira is degraded. {ECO:0000269|PubMed:16564014, ECO:0000269|PubMed:18342578}.
Interaction partners:
- Maternal protein pumilio
- FI06716p
- Uncharacterized protein, isoform B
- Miranda, isoform A
Sequence:
MASSPTPSLDSMRGGANSIESYEHAGYLSDSPLTLSGSSPPASDSAICSDEYTGGSSVKSRSEVTVINGHHPISASVSSSSSASSSSCSSSSSSSSSSSSSSSSTSGLSGCGSTSSSVISANNVASSNGPGVIGSNLQSSNNGGNSGISSLVVGAGKGSNSSSNSSSSNTSANGSPPRCTACKSKCSDAVAKCFECQSYLCANCVTAHEFMHCFNGHNVCLIKGFEASTTGTPLSVGSPSNNPASNEFKYASSLTMMLQQQQQLDSQQQQQQQQLLPAQPMSQLSKIVLAAAAQANSQEQQREDSIYGSLHPQQQQQQQQQQQRQLFCPRHKQELLKFSCRTCCILVCKECIVLEHSTGLHELENVQSPGMTTSTGSTANESALQTLLADMRGKIGEIVGIAGNSDQNLTKVKLQYQKAHNELNETHQFFASMLDERKTELLKELETLYTAKVNSNNSWQQRSRDLIDKGLATCEAVERSPAPPSSLLTEALLLRKSLEQQLQTGIQEMQLPFEIEFMSNYQSIQAGVRNTFGYIRANSSDGGPTGMSLTSNGHGKQPPIARPTQSASNSSASSAGSGHHGHHQQSHHHGHHNHHQTAHHQQLQAQSSLHGLGLGLSGASLLDSSSSAGGAVGAFSNGGLLLGGRDRNALAVEQHFGELMPKRGGGGYTGSNGSATSAVAHYNPYEKWSNGGSDNLFSSVTSGVSGSSAVADAFASLSAVGGSVVSGAGAGGSTVSSESLLDLTNKLLSATIYPPKSQIKRQKMIYHCKFGEFGVMEGQFTEPSGVAVNAQNDIIVADTNNHRIQIFDKEGRFKFQFGECGKRDSQLLYPNRVAVVRNSGDIIVTERSPTHQIQIYNQYGQFVRKFGATILQHPRGVTVDNKGRIIVVECKVMRVIIFDQNGNVLHKFGCSKHLEFPNGVVVNDKQEIFISDNRAHCVKVFNYEGQYLRQIGGEGITNYPIGVGINSNGEILIADNHNNFNLTIFTQDGQLISALESKVKHAQCFDVALMDDGSVVLASKDYRLYIYRYVQLAPVGM
Protein: Mitosis inhibitor protein kinase mik1 (EC 2.7.11.1) (P30290)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Protein kinase that acts both on serines and on tyrosines. It acts as a negative regulator of entry into mitosis (G2 to M transition). Phosphorylates and inhibits cdc2.
Interaction partners:
- M-phase inducer phosphatase
- G2/mitotic-specific cyclin cig2
- Cyclin-dependent kinase 1
- G2/mitotic-specific cyclin cdc13
- Serine/threonine-protein kinase cds1
- WD repeat-containing protein srw1
- Cohesin subunit rad21
- Tyrosine-protein phosphatase CDC14 homolog
- Mitosis inhibitor protein kinase wee1
- Protein phosphatase PP2A regulatory subunit B
Sequence:
MDSSTTIPITPTRTPCFFNISSSFNEHSPLNFYDEPIYNFSSGHEENQSHKSSKLTFFKPSNTKRSPHTPMQNNAKAIRLSTTVRHGIFKNSDLDGCSKPFAFSSGLKLSKKIVDASTPIDLKRKRAVTSLSTGLLSKREKWSLWEGNLTNPRSEQPHTPCKKGTKIKLKPPQSPLSPTTSLLARKCKHIDLDTFSRLDHPNSDSSDETFEMEELPSLSYGSEDLLEFCETPCKSQPIFLSSSHVNNWDEKDVPSSLSWTPTSPIFLNINSADDYEEEEDWTSDLRIRFQQVKPIHESDFSFVYHVSSINPPTETVYVVKMLKKNAAKFTGKERHLQEVSILQRLQACPFVVNLVNVWSYNDNIFLQLDYCENGDLSLFLSELGLLQVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSMVDLEGDRVYIAPEILASHNYGKPADVYSLGLSMIEAATNVVLPENGVEWQRLRSGDYSNLPNLKDLLLSKEKVQINKVRCAESLQCLLQRMTHPYVDCRPTTQDLLAMPEMIFISEHSQKAAIIYEDHNSWLET
Protein: Aspartate--ammonia ligase (EC 6.3.1.1) (Asparagine synthetase A) (P00963)
Organism: Escherichia coli (strain K12)
Function: May amidate Asp of the extracellular death factor precursor Asn-Asn-Trp-Asp-Asn to generate Asn-Asn-Trp-Asn-Asn.
Subcellular location: Cytoplasm.
Interaction partners:
- Asparagine synthetase B
- Aspartate carbamoyltransferase catalytic subunit
- Argininosuccinate synthase
- Aspartate carbamoyltransferase regulatory chain
- L-aspartate oxidase
- Adenylosuccinate synthetase
- L-asparaginase 1
- L-asparaginase 2
- Aspartate aminotransferase
- Aspartate ammonia-lyase
Sequence:
MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL
Protein: Septin (A0A384N6H6)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, cilium membrane {ECO:0000256|ARBA:ARBA00004309}. Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Midbody {ECO:0000256|ARBA:ARBA00004214}.
Interaction partners:
Sequence:
MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAALNTRKTLLWEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDGDGGALGHHV
Protein: Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32) (P12318)
Organism: Homo sapiens (Human)
Function: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19011614}; Single-pass type I membrane protein {ECO:0000269|PubMed:19011614}.
Interaction partners:
- Tyrosine-protein kinase SYK
- C-reactive protein
- Serum amyloid P-component
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase HCK
- Immunoglobulin heavy variable 4-38-2
- High affinity immunoglobulin gamma Fc receptor I
- Low affinity immunoglobulin gamma Fc region receptor III-A
- High affinity immunoglobulin epsilon receptor subunit gamma
Sequence:
MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDKNIYLTLPPNDHVNSNN
Protein: UDP-glycosyltransferase 84B1 (EC 2.4.1.-) (O22182)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses low quercetin 7-O-glucosyltransferase activity in vitro.
Interaction partners:
- Indole-3-acetate O-methyltransferase 1 acetate carboxylmethyltransferase 1)
- IAA-amino acid hydrolase ILR1-like 2
Sequence:
MGSSEGQETHVLMVTLPFQGHINPMLKLAKHLSLSSKNLHINLATIESARDLLSTVEKPRYPVDLVFFSDGLPKEDPKAPETLLKSLNKVGAMNLSKIIEEKRYSCIISSPFTPWVPAVAASHNISCAILWIQACGAYSVYYRYYMKTNSFPDLEDLNQTVELPALPLLEVRDLPSFMLPSGGAHFYNLMAEFADCLRYVKWVLVNSFYELESEIIESMADLKPVIPIGPLVSPFLLGDGEEETLDGKNLDFCKSDDCCMEWLDKQARSSVVYISFGSMLETLENQVETIAKALKNRGLPFLWVIRPKEKAQNVAVLQEMVKEGQGVVLEWSPQEKILSHEAISCFVTHCGWNSTMETVVAGVPVVAYPSWTDQPIDARLLVDVFGIGVRMRNDSVDGELKVEEVERCIEAVTEGPAAVDIRRRAAELKRVARLALAPGGSSTRNLDLFISDITIA
Protein: Brorin (Brorin precursor) (von Willebrand factor C domain-containing 2) (B0I1T8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
- Coiled-coil domain-containing 36.
Sequence:
MLHSAAMTTGLIFVTWLLYTSARGNPIVSVPEGGEKERLERVLTQAKEGALSPSAKQRLEELNNLELEGIKGGNRSTSGRTRPNLSSLRKGSKLQGKTLEAWSEQESLKQTEGAPTEEANVSLDAIDEYAYPDYRGKGCMDETGFVFAIGEKFTPGPSTCPCLCTDEGPLCAQPECPKLHPRCLRVDTSQCCPQCKEKKNYCEFRGKIYSSLEEFKVSPCEKCRCEPSGEVLCSVSACPQTECVDPEYEPDQCCPVCKSGPNCYADTSVIPAGREVKIDECTICYCTYEEGTWRIERQATCSKNECQPS
Protein: Single-stranded DNA-binding protein (SSB) (O25841)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
Interaction partners:
- Small ribosomal subunit protein bS6
- DNA polymerase III subunit gamma/tau
- Replication restart protein PriA
- DNA topoisomerase 1
- DNA polymerase III subunit alpha
- DNA polymerase III delta prime subunit
- Ribonuclease HI
- Small ribosomal subunit protein bS18
- Large ribosomal subunit protein bL21
- Small ribosomal subunit protein uS10
Sequence:
MFNKVIMVGRLTRNVELKYLPSGSAAATIGLATSRRFKKQDGTLGEEVCFIDARLFGRTAEIANQYLSKGSSVLIEGRLTYESWMDQTGKKNSRHTITADSLQFMDKKSDNPQANAMQDSIMHENSNNAYPANHNAPSQDPFNQAYAQNAYAKENLQAQPSKYQNSVPEINIDEEEIPF
Protein: Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R) (Q01727)
Organism: Mus musculus (Mouse)
Function: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q01726}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Pro-opiomelanocortin
- Agouti-signaling protein
- 5,6-dihydroxyindole-2-carboxylic acid oxidase
- Tyrosinase
- Microphthalmia-associated transcription factor
- P protein
- L-dopachrome tautomerase
- Membrane-associated transporter protein
- Mast/stem cell growth factor receptor Kit
Sequence:
MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIAITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDVLICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITYYKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAATLTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRSQELRMTLKEVLLCSW
Protein: Primary septum glucan endo-1,3-beta-D-glucosidase (Glucan endo-1,3-beta-D-glucosidase 1) (Endo-1,3-beta-glucanase 1) (EC 3.2.1.39) (Laminarinase-1) (Q9UT45)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Cleaves internal linkages in 1,3-beta-glucan (Probable). Has a role in cell separation where it is required for the degradation of the primary septum after completion of cytokinesis.
Subcellular location: Cell septum {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:12665550, ECO:0000269|PubMed:18466295}. Note=Localized in a ring-like structure around the septum. {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:12665550, ECO:0000269|PubMed:18466295}.
Interaction partners:
- Glucan endo-1,3-alpha-glucosidase agn1
- Metallothionein expression activator
- Protein adg1
- Serine/threonine-rich protein adg2
- Septin ring organizing protein mid2
- Probable secreted beta-glucosidase adg3
- GTP-binding protein rho4
- Glucan 1,3-beta-glucosidase 1
- Chitin synthase regulatory factor 1
- Forkhead protein sep1
Sequence:
MSSYLRSFIFGLLTISLAQCSPILKDTKDTKFSTGSNISLKKRDTNVFDSVVDTINPASYFGTVSHPVTPAGVSTDSLSSPIETNKFFDNNLLGSRTNFMYADPFRYWWQSSDTMGGICIAHTDDNQRVMDTDDTIPSYYYEPIGICSLGFGASGITSNTDPIVDEIDQMSARFTFSWDSSSMQLTLTEGMAVTTAVYTNAIPQIFSSTLYINDFVEVPGTSAVQKYRVTMSDNHVWLIYIYGDSLTLTESTSQMLVGSNTFNGYIQIAKIPLGDGTAEALYDTYAGVYITGISISGYVEDAVGYYSFDFTTAGDTSVEPLFFLLPHQVDTAVSGTKVTSIVLASLVSGDMNAAAGNSITFAEAIPQDIGFLPWSPTGGQIGYSEEALEIIAEVAGTELGEDFSANSNLNSMYYSGKVLAKYAMLCVTINDILGDETSSEQCIQKLEAAFARFVDNQQIYPLTYDNTWKGVVSVAGLSGDSLADFGNSYYNDHHFHYGYFVFTAAVIGHIDPDWINTGNNKEWVNFLVRDVANPSSNDPYFPKHRMIDIYHGHGWASGLFESNDGKDEESTSEDYNFFFGMKLWGQVIGDSDMEDRANIILGIERNALNKYMLYADGNVQPTSMQPNYVAGITFMNKITHTTYFGTNIEYIQGIHMLPITPISAFIRGPSFVLAEWNALLASVIDYVDSGWRSLLYANLAIAEPEESYEYFSSSDFNTDYLDDGASRAWYLAYAAGLWANDAVYYPVSSSSTTTTSTSTGSVTTTSTTATASCTLPISYTSTPTTTSISGTCNGATFDASLYVCDGTVLCPIVNGVSYQNCNGACYNPSQYGCDNGALGPVQSSSTTSSITPTPTTTSSITPTPTTTSTTTTAQSTGMQLCGSNYYDASSYYCDNDQLCPIIDGVDYLSCNGACYNPSQYVCSDGSLSPNTVTTTKATTTFTPTPTTTTTPTPTTTSATSTNVIAQCGSAWYDSQSYICYGNILCPIINGSPLLACGNACYDSSIYGCSNGALVAA
Protein: Stefin-2 (P35174)
Organism: Mus musculus (Mouse)
Function: This is an intracellular thiol proteinase inhibitor.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Stefin-3
- Cathepsin B
- Caspase-1
- 2010005H15Rik protein
- Stefin-1
- Cystatin-A
- Cystatin domain containing 5
- Cystatin domain containing 4
- Cystatin domain containing 6
- Cystatin A family member 3
Sequence:
MTEYTRKIKGGLSEARPATSEIQEIADKVRPLLEEKTNEKYEKFKAIEYKVQVVQGLNYFIKMNVGRGCYLHINVLSGISSENDLELTGYQTNKAKNDELTYF
Protein: Protein mahjong (DDB1- and CUL4-associated factor-like 1) (VPRBP-like protein) (Q9W2F2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable substrate recognition component of tsome E3 ubiquitin-protein ligase complex (By similarity). Plays a key role in cell competition via its interaction with l(2)gl.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Cullin-4A
- DNA damage-binding protein 1
- RING-box protein 1A
- Falten, isoform B
- DET1- and DDB1-associated protein 1
- RING-box protein 1B
Sequence:
MSEGSGSENAAAAEAAAEAEAATEAALMAEAVAVAYQSDEEEQPEAEDMPEQAGDNQEEDAAEQQDGGEPEADEDADADDAMSVENAENESDSGGNAEETAAADRRQATKKELTQIIDKWEQQQTQNGYDPVPTLRSLAEIFEREKDVYRRKDPDPLDSRHPYRADPSCQYGLLLKLLFRKDTFMGKLLNDYLRENYFSRQNVSRSSLELNILACRLILEIMPGMETSAVFQTAEGDGTINRIYSWAEDSIEPLQSYATGLLAEAMEVSDIAINFRDLNIRLVPKMIKRLHMLLAISKSATSDVNTSMHNLSADSSTAGMLSWVACASNASAPQSPQHNGSGLGASSSQHGDASNMSILFENSRDAFSVSRYYKRMYIPLHPATADTSQMLIMRFLTSLGEYQEFLAMAFENNVMQLIFGYLENLDRRDTCLAYEVLKYLASLLCHKKFALEFISHGGLELLLKVPRPSLATTGVSIAIYYLAYCEDAMERICSMQRPLISELVRYALWILGRCHDSSKCHATMFFSLSFQFKVILDEFDAQDGLRKLYNVISVLKILDPSHNDSDNDSDFNEDVECASRQMVRHVCVALKRYMEAHFFYKYNSFLCQTNAASPAPSSAHYFNQNPTVAAKLTFDQLNDQIRTLQEHTSIRAHWQPVDQLMKLGGITMLLRIIAFSYDWVNSGRSETVRSALDVLSVCCIIPRVYVVLCERLLMLDKTTTSGFCSVLGAAAGEISSDAEVIKSALAVLCHCVCSPIIRKDSGTSLIKFGTSSRKNKANHKYAEELIERVWESVCSNNGIVVLLSLMQTKGPITDADCIRGMACRALAGLARSDRVRQIVSKLPLFASGQLQTLMRDPILQEKRAEHVIFQKYALELLERVSGKTKPLNNPLDPSLSNMHKANVIAQTRIQYNKQQLYQLIFEHLESNGLSQTAQMLQREVGLPLQTPTTRSFHQSPFDYKSLPSGSSSLSRNRLRSRMQDVNAAIMGNGDLNRSFGEDSSPAGAGGSNAGDGVSIPNFSSLNTTQTPIKIRRTDRSSVSRSIQKQAMEPGGMSVGLAEDGQLHPKRITLNTIVTEYLTNQHSLCNNPVTTCPQFDLYEPHKCPDPKPSRLLSSNYNLTSRHARTQAGFNTSRFDRRYVHTHFSPWRSIRSADYEDLEFTCCDLAGKYIIVGTQQGDGRVFNMNDGVEQFFSNCHNFSVDAIKANRAGDLVITSSFWRTPTSILWSIADDEFKLKLRLPDVTYCEFSQTVQDRLLGTQNECATLFDINTGSKVASFTPTIPNLYTKNRATLCRTDELILSDGVLWDVRSGKEIHKFDKFNQCISGVFHPNCLEIIANTEVWDLRTFHLLQTVPVLDQRNCTFSPMHVIYGASLGADRDHDMETTTYDTSFNVLDAYDYSSIATIDVKRNINDLSVSANGSLIAVVEDYSGYESKQETYVKIYAVGVKKSERSEEEDDEEVPESDEDGSDTGSENTFAIGQNLLGFPLLRNLHGSDNDDEDLDEDDDDGEPLDSDDDSDDDDGSDNGDDDGDFDVLEYFDRSSSDD