Protein: Protein furry (Q9VT28)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in the Trc/fry signaling pathway by promoting trc kinase activity. Plays a key role in maintaining the integrity of polarized cell extensions (arista) during morphogenesis, regulates the actin cytoskeleton. Plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching. Together with trc, has a role in regulating microtubule-sliding during neurite outgrowth.
Interaction partners:
- Serine/threonine-protein kinase tricornered
Sequence:
MDQLELQDDLFGLEAGVAGTNQNPNEQHLSDPAASPSTSSPANNNATAGAATTSTATVITAVGGAGGGVAAAGVGVVTPTKSPQRNAFQEDAYQANLAGGDSVDNIESAQLDGGNPSGGSPGQRHSINSAEYTSTPKTTRSGPNGSTTASGTTSPINYQLPGDDYPYGIEYESQQLLYQQQQQQQQQQSQQQQQQQQQQQQQLPVGDVEQSSAVTYQSLPVSRQSYASPPALIIPQRQSLLPWGAHSRSSIINVLPSYTQAEMHALAARVASVETSAPRPGEIVMRNLFSDFTAQAEKKIELVMLESADKNLSKLLQRGEDQQFDQLLSALGSVAEHCLPSLLHTLLAWHRRQLSDMEIKNDLKKPAPSGSSSQAATNKPTVDLDFQLQRREAAVEFIFCLALIEILKQLPYHPGHEDLVRSIENLAFKHFKYKDGLQNNPNALNIHMIADLYAEVIGVLAQSRFASVRKRFMSELKELRGKEVSPTTTQSIISLLMGMKFFRVKMVPIEEFEASFQFMHECGQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCVKNFVELLYVQTLDASTKSKHRLALFPLVTCLLCVSQKTFFLTNWHYFLAMCLSNLKNRDAKMSRVALESLFRLLWVYMIRIKCESNSATHSRLQSIVNSLFPKGSKGVVPRDTPLNIFVKIIQFIAQERLDFAMREIVYDLLCVGRSIKLILNPERMSIGLRAFLVVADSLQQKAGEPPMPRTVPVLPSGNTLRVKKTFNKMYVLLTDDTARSIGMSTYFPHVRRVFVDILRALDVHYGRPLMMTNTQNQNKEPDEMLSGERKPRIDLFRTCVAAVPRLIPDTMTPHELVDMLSRLSVHMDEELRILTHQSLTTLVIDFPDWRQDVVHGYTQFLVRDVTDTYPQLLENCTRILFTFLNIWRCATNVNGNNTTSAPSGATNVVNTSQAKMTTATTTTTVVQATVVQVTSAPAKDTASSQLSKQQHLNTASSAASSITTSSGMSSITQHTVLNMASDVGKKNEIPLATTLHFVEGFALVLLCNYRTYLRKLAALILKEVKNLMRALGIPETEPPLIDVMDRCVPGIIEKCLPQLPQTEKTAILNANCIDLQWIAERSSGVWLAGLTDDNSKSSTSTLNLSQSSSTPNASATAASSPQLPFDPWATCLFGLLERQNVLQQCPSAVAQAWPICFTRLNALYSVIDPTPVSDNRASLLRSSAPTKKVPTESQKDSYLRLWRNQVACAMRLVPQIPSVAVRCASPDLSLSSSPDSLNADRSDKSAMGSASPQALYKLVVPLLRCEVVDVRDAAVNALGLINHDALKDLMEELVVYIREAVDCKQENMRRRRRRDALRLQVVRVLEKIAENGTFGVSTCVLERDTMSLHPTFVLYISGAMGYLTSETDKDNLSIREVKAHFCNFIRKMIKNFPLEACATLLSRVLKRNLFNLFAAWCGSFSKPLGYTMQSDHTLEEEKLQFSALQAMSALLCCGQIFNPSYLQDDSIIYKWLDMLLTSKNEKIYQLARDTVVLLLESNPDIGQLLEWVIDRCYTSTPREADACFLALASIFSAKEYPCDHYTSVITVTLLMTGCPRVEVHATALQLLQILDKRFFGSVVGTLHSDSDKEDDKVGTLDVLLSSAYCRSQRFLSKQLAQLRPELTMSIFSEITHRFQSAREDVRALLLQCLLPWLQNMELVATSVPPATPLSYIMYFPDSGTRGRREGTGSTEATEMILNNLFYITAKFSDAHPRDIEELWGTLCQFWPNNLKVILRYLVIMSGMAPTELLPYAKRVALYLVRSCPDRLLDELMAELQTVETLNCLIERTETPPFYRLTSMRKASSHSADGQAAGGINDSRIQDLAVEKGTIHTKRHSGEDPMKIGTCKSDSGIRAYTQAAAAAAAAAVTPGSSGNRPPRGADKIRAASGPSILPRPEDILINDPELRQEENVELRGTSDAAPNGHPHPLPMPEYGGYFAPLTEFLPDVSLPISGFHRCNVAVMLLTDIVVDGIPGIDWTLHLPLMLHILFLGLDHTRIIVREHCKQLCVNLLIVLAEHNDHLTVARILLNSETSKLDLGLTVPALPVIDNNFTELHQQFDSYLLHVSPQAAAYALQHNLSSSTIIAAHHQNLSQTPQSQQQTGSQNGQTTTPPGLTATPAALQINPNNSENSEVPLIHPDEHAPPQPGPSMPIAHVIKSLLKFLAQDTCQPLWNYEDITAKVWAVKSAEQLSCFLKHMVKVFADSYPQARIAERWAQTALQLGLSCSSRHYAGRCLQIFRALNVPINSRMLSDILSRLVETVAEQGEDMQGYVTELLLTLEAAVDSLDSDFRPLDVMKDIFKSTPNLNNKDGGPNSILPGKKSPSGMTPQSSNYSIPSHGRSTSYSVSYCGRKANNSPCDKQVELRNRSSGIDLERSVVCKFGVGGGGAGSALSRSRSAQSLKMLGDTATQDDKMTILAQLFWLSVSLLESDYEHEFMLALRLLTRVLHRLPLDRPDARDKVEKLQQQLKWTAYPGVHALLLKGCTHSATYEPTITLLSQFAPLLTLPVCDPTQSCAFPMNVIALLPYMLLHYEDANEICIRSAENIAQVSTELGAKLENLGTVMTLYSRKTFCKESFQWTKCVVKYLHDTYAHMGLHMVAFLIEVLEKGPQQVQVPVLNVIHCMLHYVDLSAPQAQSINADLLRAIGKYLDTAYWKDSLKILKLIVTRSSSLQVVPPSDGSSAGLSFSFYGAYPDSDMFCKKELAGRTMEFTFDVSQTPLIGRRILLKTEEPVAGGAVSTTGSSSLNSTLTNATTVTVAPSAAQQQTNVQMQQQRANTNVAALAAAAAAQHQQQQHAIGAGSSVVGTPNSPRRSASLSPADTVPLSGWKRPWMSQCRVRECLVNLLTTCGQRVGLPKSPSVIFSQSSDLMERQSSAASSTEETSGPQGDLSSGSRRDDGQPDFTVFKDFDFLEYEDSIAGESTDNFNWGVRRHQLFEGDEDRLNCGSGIGGSIKGGHSSAFEDSFSDKTPILSKRKRQIADDSSDEEAESESPLDEDHRQSFLKSGYSAVPPTSLSLRERRRRNSVSRSDTSGSSAGDLGDLTPCNASPHLPGIIRFSAAIHDEAEENWRRQVQALLVNQPSAHTSELLQQLYRLIKELTFKTVNISKEAKKFFTGIGSQLGNRISLFTDLLSSRADPPQVWCSELQATSPKLFETLRFNVLEVQEHLETFFDRKDQVLECLDAVKTSCKLSLFNEADVAASGLELPSTSSIVYMPFDPASTEVVLDLGRSLYKLMFQLLLLIESNHKISSNVVNHFRMNEDMHDISDLYALVRDALVRYISEAELDCLESSTSTEGEHTPTPSPGLPMTPEEFEAVLTEHIDLQRWPSAIAHVRQYRRISTLNASGYQNVTIFSYNSADNRQKWDEISVILNAYAHGIMKDRTEAFIVSKSDSEVFEIYAILSENLYQVSSALTNMEISMKSYSAGSASGNSHRSEQDIVTNL