wanglab/gogpt-training-data huggingface dataset:
Protein: mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Q6FXI1)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome B complete sequence
- mitogen-activated protein kinase kinase
- High osmolarity signaling protein SHO1
- mitogen-activated protein kinase kinase
- Serine/threonine-protein kinase STE20
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- Candida glabrata strain CBS138 chromosome L complete sequence
- Candida glabrata strain CBS138 chromosome D complete sequence
- Candida glabrata strain CBS138 chromosome M complete sequence
Sequence:
MSHIEFLERAGCSQYADLFEEYSLTDINDLMHIDRDILLEIGVKKLGDRIRILKESKKLQEPKDDAKHVQQLQELISNISELSTTSTNINEEVITERHCVIFILNDGSAKKVNISGCFNADSIKKRLIKRLPSNLLAVNTDGQTTQESSDYDVFIVDYSKNVLRLLYDIELVTICHSNDRVEKNRLIFVSKDQTPTDRAINASKKLYLKTITALNHIESYYDAQSGMPNTPVTQDGTLRIHKEGKDKLRKIFDQRPPSEFISTNIAGYFPHADTKRLEKALRESYRQSARISMKSNNSRHISSESNRVGDILLKHSNAVDMALLQSLDNNNAPSSKPEVIPPSTPQEEDNEGKIKLMEETESIDDYYMNSDEEHGTVSLPTKIVTPKNWLKGARIGSGSFGTVYLGMNAQTGELMAVKQVEIKPAIAATADANVEDKNAEKNVAKAPSTNLHRKMIDALQHEMSLLKELQHENIVTYYGSSQEGGNLNIFLEYVPGGSVSSMLSNYGPFEEPLIVNFTRQILIGVAYLHRKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNQENQDKRTSLQGSVYWMSPEVVKQTATTSKADIWSTGCVVIEMFTGKHPYPDFSQMQALFKIGTNVTPEIPSWASPQGRDFIRKTFELDYQRRPTAIELLQESWLESHII
Protein: Glucose-6-phosphate 1-dehydrogenase 2 (G6PD 2) (EC 1.1.1.49) (P9WN73)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
Interaction partners:
- 6-phosphogluconolactonase
- Transaldolase
- Transketolase
- Glucose-6-phosphate isomerase
- 6-phosphogluconate dehydrogenase, decarboxylating
- OXPP cycle protein OpcA
- Glyceraldehyde-3-phosphate dehydrogenase
- Probable 6-phosphogluconate dehydrogenase,decarboxylating Gnd2
- Probable phosphoglucomutase PgmA
- Glucose-6-phosphate 1-dehydrogenase 1
Sequence:
MKPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWAAHGTPDAYEAGTWGPESSLEMLRRTGREWRRP
Protein: Suppressor of tumorigenicity 7 protein-like (ST7-related protein) (Q8K4P7)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- RAD50-interacting protein 1
Sequence:
MADGDYFAEAARAVGCPHAPVPGLGLGPPLGWKERLKAGLANSGSTLWFLAGLGLLYALRVPLRLCDNVTAVTGFLSSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSISHLRPLMGGTESSISEPGSPANSRESETLRHHHLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDHQTFFTCETDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERLFKQALRAGEIIYRRSQQCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKTRTVSDKFSPETAFRKGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHHVSVYPKKELPFFIHFTAGLCSSTAMLAFLTHQFPEVMGVFAKAVSMISRTCVEYL
Protein: Frizzled-3 protein (Q8CJC4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAVSWIVFYLWLLTVFLGQIGGHSLFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCDEPYPRLVDLNLVGDPTEGAPVAVQRDYGFWCPRELKIDPDLGYSFLHVRDCSPPCPNMYFRREELSFARYFIGLISIICLSATLVTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDRVACNASSPAQYKASTVTQGSHNKACTMLFMVLYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQMSRPDLILFLMKYLMALIVGIPSIFWVGSKKTCFEWASFFHGRKKKETVNESRQVLQEPDFAQSLLRDPNTPIIRKSRGTSTQGTSTHASSTQLAMVDDQRSKAGSVHSKVSSYHGSLHRSRDGRYTPCSYRGMEERLPHGSMSRLTDHSRHSSSHRLNEQSRHSSIRDLSNNPMTHITHGTSMNRVIEEDGTSA
Protein: Retrotransposon hot spot (RHS) protein, putative (Q57X01)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNQNGGSVGDTWNVLNGWLNGAYRPMKRQADRENENPSETGEGKSLEEKLYDSIYNAKWSYVMSGYDTEPLGMKVFDGRPQQMWTKEEVDVSQTPETVNEPLPRHGNLEIAVLTSQMGWPYTSFQPQEKDYDINHKKGVEYVFNDDVYIRRETLRVWHKVEERLNKWLMGEVIVNPMAHVLIGTPGIGKSFSTAPFLLYKLLHYEASQLQIIIYVVRGKAYVFHKPIGGRAGYVTFYSNYEHASTLIDQIVRDSCKTGKIKGYLIFDVDKDHPAPVKPPGDFSGIALSSPDKRQFHEWSKQNTATHIYINCDTLKDLEAIHISRWGKIAPAYKWSPPVAKEKIEREWQEIQARIRIVGPLLRHIVDSRSYEKRAQAMQNTILKLERGDTEYFRSVIRNRAFWETHEASHKLVMVVRVKEDLLLCDMHRCKPLSSYTGEAISDRLKPFIQEKSALVSELLSNRTLAAYRFKQSGIEVLSHEDALIELAKELRGLPYTGDQIPQSVLQVLQGPRLTNPLIEVPHDSTIRAGTEIEYMILYKPQSGNFPVVDAFFFVENPKTFVGLQFTISDKHSCSTSGLFKMKRCLQSYFKHWDNFSNDMVWEIIYVQRVDSEKITKPQCCEGTIEDEGQNNKVEERFWRERVHQFSATLNERIIALYVELQVRGNNNNGVNN
Protein: Probable basic-leucine zipper transcription factor G (Q54RZ9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Probable transcriptional regulator.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Probable basic-leucine zipper transcription factor R
- C2 domain-containing protein
Sequence:
MLSVWNLPVEQQPQQQQQQQQNIINSSNNINSINSALDNILNTTSKGIQLPRFNLLNTSSSGFLTNSNDTLFLENNNNNNNNINQQLNKSVLNSSNKQLDIIKTINEISNEHKSFQPFEITPIKPQSTSTNTYNTEFGVINQNTFVLDSNKIEELRVDTSVLDPLLSLPYNIINNTTNNNNNNNNNNNNNNNNNNSNNNNSNNNNINNNNNKSNTPMKKESTIRNSNSTFEKFESPTLSTTFGLNKEELNTFTTTDMNNYVKQANMVKELSQVEKKELKRQKRLIKNRESAHLSRQRKRERLTDLEHRVEELSSNSIDINKTLSSLENENLILKAEVGQLFEVINDSPVLSALFYKIASLSQQPQKDTIGAY
Protein: Tryptase (EC 3.4.21.59) (Mast cell protease 7) (mMCP-7) (Tryptase alpha/beta-1) (Q02844)
Organism: Mus musculus (Mouse)
Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity (By similarity).
Interaction partners:
- Tryptase beta-2
- Mast cell carboxypeptidase A
- Chymase
- High affinity immunoglobulin epsilon receptor subunit alpha
Sequence:
MLKLLLLTLPLLSSLVHAAPGPAMTREGIVGGQEAHGNKWPWQVSLRANDTYWMHFCGGSLIHPQWVLTAAHCVGPDVADPNKVRVQLRKQYLYYHDHLMTVSQIITHPDFYIVQDGADIALLKLTNPVNISDYVHPVPLPPASETFPSGTLCWVTGWGNIDNGVNLPPPFPLKEVQVPIIENHLCDLKYHKGLITGDNVHIVRDDMLCAGNEGHDSCQGDSGGPLVCKVEDTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKDF
Protein: Inner membrane protein YbbJ (P0AAS3)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Protein QmcA
- Flotillin family inner membrane protein YqiK
- Adenosylcobinamide-GDP ribazoletransferase
- Probable iron export permease protein FetB
- Uncharacterized metal-dependent hydrolase YjjV
- Probable iron export ATP-binding protein FetA
Sequence:
MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGLVVWLVPLGWEWQGVMFAILTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFVLESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLHIRAVSS
Protein: Olfactory receptor (Q8VG11)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
Interaction partners:
Sequence:
MAGRNYTFVTEFFLTAFTEHPEWGLPLFLLFLSFYLATLLGNTGMIILIQKNRRLQTPMYFFLSHLSFVDICYSSVIIPQMLAVLWEHGSTISQVRCAVQFFLFTFFASIDCYLLAIMAYDRYVAVCQPLLYVTIMTEKARVGLVTGAYVAGFSSGFIRTVTAFTLSFCGNNEINFIFCDLPPLLKLVCGDSYIQEVVIIVFAIFVMPACIVVISVSYLFIIVAIMQIRSAGGRAKTFSTCTSHLTAVALFFGTLIFMYLRDNTDQFSERDRVVSVFYTVVTPLLNPLIYSLRNKEVKEAITKSLRRSKISRAP
Protein: Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Q08CK7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability (By similarity). Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons (By similarity). Regulates localized beta-actin/ACTB mRNA translation in polarized cells, a crucial process for cell migration and neurite outgrowth. Promotes the directed movement of cells by fine-tuning intracellular signaling networks and enhances the velocity of cell migration (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q9NZI8}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q9NZI8}. Cell projection, growth cone {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}.
Interaction partners:
Sequence:
MNKLYIGNLNEKVTAEDLVKTFEDYKIPYSGQFLMKTGYASVDCPDDQWAMKAIETFSGKVELHGKRIEVEHSVPKKQRTRKLQIRNIPPHLQWEVLDGLLAQYGTVENCEQVNTDSETAVVNVTYGTREQARQAIQKLNGYQFDNNALRVSYIPDENSEVDSQRGPDNGRRPGYGPRGTSRQMSPGSGIPSKHQHADIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKPISIHSTPEGCSAACRMILEIMNQEAKDTKTADEVPLKVLAHNNFVGRLIGKEGRNLKKVEQDTDTKITISPLQDLTLYNPERTITVKGSIEACCLAEQEIMKKVREAYDNDIAAMNQQTHLIPGLNLGAIGLFPPSSAMPPPALGNSVPGPPYGPMGASEQETVHVYIPAQAVGALIGKKGQHIKQLSRFAGASIKIAPAEAPDSKMRMVIVTGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIKVAAAAAGRVIGKGGKTVNELQNLTAAEVVVPREQTPDEHDQVIVKIIGHFYASQLAQRKIRDILTQVKQQQKGGGMGTPQGPHPQGMTELGSPQGLAQEPRRK
Protein: Aminoacylase-1A (ACY-1A) (EC 3.5.1.14) (ACY IA) (N-acyl-L-amino-acid amidohydrolase) (Q6AYS7)
Organism: Rattus norvegicus (Rat)
Function: Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Ornithine transcarbamylase, mitochondrial
- Arginase-2, mitochondrial
- Arginase-1
- Aspartoacylase
- Argininosuccinate synthase
- N-acyl-aromatic-L-amino acid amidohydrolase
- Beta-ureidopropionase
- Ornithine aminotransferase, mitochondrial
- Delta-1-pyrroline-5-carboxylate synthase
Sequence:
MTTKGPESEHPSVTLFRQYLRICTVQPNPDYGSAVTFLEERARQLGLSCQKIEVAPGYVITVLTWPGTNPLLHSILLNSHTDVVPVFKEHWHHDPFEAFKDSEGYIYARGAQDMKSVSIQYLEAVRRLKSEGHRFPRTIHMTFVPDEEVGGHKGMELFVKRPEFQALRAGFALDEGLANPTDAFTVFYSERSPWWIRVTSTGKPGHASRFIEDTAAEKLHKVVNSILAFREKERQRLQANPHLKEGAVTSVNLTKLEGGVAYNVVPATMSACFDFRVAPDVDMKAFEKQLQSWCQEAGEGVTFEFAQKFTEPRMTPTDDTDPWWAAFSGACKEMNLTLEPEIFPAATDSRYIRAVGIPALGFSPMNRTPVLLHDHNERLHEAVFLRGVDIYTRLVAALASVPALPGES
Protein: Neuroligin 3, isoform B (Neuroligin 3, isoform C) (Q9VIC6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Neurexin 1, isoform F
- Peripheral plasma membrane protein CASK
- Liprin-alpha, isoform E
Sequence:
MVMLLSKRQLPPSAATRTRRKVPPTRRRSTWALSSLLALVVLDICIARCLAAGISYSSNSGNLSTSQKSPSSANNGGLVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDDEDNNIPSDASVKPLNPPYISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGGGKIYPDDMMDGDHAGGAASASQDSDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKRQENGQMPNNICGDLETLTIHAKSDPATILSHHHAMQHHQLPPPEFADIPHRAPPPPKHMKSLQDPGGGGSVSGAVGVSGVVQMPPPHALQVMGNQCGTLTKKSCMKQTQAQAQQHSPAQQQQQQQQQQQQHVVTHQQHLQNHHNQSMTTVLTTAGGLVVPTPPTVPVIVASTTQHQQHQQQHQQQQHQQQQQQQQQQHPLMDELRV
Protein: ATP synthase subunit beta, chloroplastic (EC 7.1.2.2) (ATP synthase F1 sector subunit beta) (F-ATPase subunit beta) (P0C2Z7)
Organism: Oryza sativa (Rice)
Function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01347}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01347}.
Interaction partners:
Sequence:
MRTNPTTSRPGVSTIEEKSTGRIDQIIGPVLDVTFPPGKLPYIYNALVVKSRDTDGKQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTSATFPIHRSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNLEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPRIVGNEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEASTKAINLEEENKLKK
Protein: Hydrophobic dipeptide epimerase (EC 5.1.1.-) (Q834W6)
Organism: Enterococcus faecalis (strain ATCC 700802 / V583)
Function: Catalyzes the epimerization of L-Ile-L-Tyr to L-Ile-D-Tyr (in vitro). Catalyzes the epimerization of dipeptides, with a preference for substrates with a hydrophobic or basic amino acid in the first position, followed by an aromatic residue in the second position. Has epimerase activity with L-Ile-L-Tyr, L-Val-L-Tyr and L-Arg-L-Tyr (in vitro).
Interaction partners:
- Transglutaminase-like domain-containing protein
- Pheromone binding protein
Sequence:
MKIKQVHVRASKIKLKETFTIALGTIESADSAIVEIETEEGLVGYGEGGPGIFITGETLAGTLETIELFGQAIIGLNPFNIEKIHEVMDKISAFAPAAKAAIDIACYDLMGQKAQLPLYQLLGGYDNQVITDITLGIDEPNVMAQKAVEKVKLGFDTLKIKVGTGIEADIARVKAIREAVGFDIKLRLDANQAWTPKDAVKAIQALADYQIELVEQPVKRRDLEGLKYVTSQVNTTIMADESCFDAQDALELVKKGTVDVINIKLMKCGGIHEALKINQICETAGIECMIGCMAEETTIGITAAAHLAAAQKNITRADLDATFGLETAPVTGGVSLEAKPLLELGEAAGLGISH
Protein: Eukaryotic translation initiation factor 4G1, isoform A (Eukaryotic translation initiation factor 4G1, isoform C) (FI02056p) (Translation initiation factor eIF4G) (O61380)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQQAIPTLPTQSDIDKAMQPHSAQNMYVSTGNNNSGNTRSNPQSGGIFRGPPSTPNAPRGASGGATRHVHVQPMYSQPLHQNMVLQQYTQYNPRQQTFPASHLQYAPAPMPYYQYQYVPTLQQQPPHTRSAVTVNTNVNVGNNLQPVQSGPNGPLPVPGASSSQIQLLTSTVQPGASTVMGVGGPGSTMGQVGVPPMVGVGVMTTSVQPQPVQVQPASRRRHQHRLQIIDPTTKKNILDDFDKTKSNTDNEFSDQVTSTNTPATVLSEGPIRIPQQESVGLNNLTSTSSQGSESRTNAPYIPIETTPISRTDVGPTPIVSAMTDAPSVEILPTPQRGRSKKIPIVSPKNVSESIVAPITDETDDAGSTPISRATEESMPPNQTHPNLLISDSSKHKQAVSNSEISKDAPTGLKEMHVAELESSVASENHPAGILDVNVNKSSQSLDFSADPEIDSIGAISPTSPNAVSPILHEVLDNTELSKKLENSTTERFKDSQSVEKPTHQELSLRNATDETEISAMALQDVNSLDNNQIEKTYPSKPKLNVDVSEDISSRESAIKSTSTKNTGVDVGLQSDSKPETTLNDKQDSTDLKVKVSAKISSIINYNEGQWSPNNPSGKKQYDREQLLQLREVKASRIQPEVKNVSILPQPNLMPSFIRNNNNNKRVQSMVGIIGNRSNESAGNYIGKQMSMSGVQSGGGRSSMKGMIHVNLSLNQDVKLSENENAWRPRVLNKSDGDSDAKSALEKDELVRRVRGILNKLTPERFDTLVEEIIKLKIDTPDKVDEVIVLVFEKAIDEPNFSVSYARLCQRLAAEVKVIDERMESETKSNSAHFRNALLDKTEQEFTQNVSQSTAKEKKLQPIVDKIKKCTDANEKAELEAFLEEEERKIRRRSGGTVRFIGELFKISMLTGKIIYSCIDTLLNPHSEDMLECLCKLLTTVGAKFEKTPVNSKDPSRCYSLEKSITRMQAIASKTDKDGARVSSRVRFMLQDVIDLRKNKWQTSRNEAPKTMGQIEKEAKNEQLSAQYFGTLSSTTPGGSQGGSGKRDDRGNSRYGESRSSSAYGGSHSQRGDNGNLRHQQQNNVGGNVSGGAGHSNGNNDENTWHVQTSKGSRSLAVDSNKLEGLSKLSDQNLETKKMGGLTQFIWISSDTTRLSSAPTPTPSNPFAVLSSLIDKNSNERDRDRSGPRNKGSYNKGSMERDRYDRGMHSRTGSSQGSRENSSSRGGQQGRTLLSSSVQKSTSHSKYTQQAPPTRHTVKAQSSVGSSNVNTGPLYRGSEQQTSATFSQTTRSVAPVAVFIEASETDLKLIKSVVSEIVDLSAASKEVTPGAVSCIKRVPEKLRCSFIYYILTDYLHLANVGKQYRRYLSIAVSQLIQQNYISADHLRLAYNEFTVYANDLIVDIPELWLYILQFAGPLIVKKILTISDLWNNNLKENSPSNVAKKFLKTYLIYCTQEVGPNFARNMWIKFNLKWSDFMPESEVADFIKFNRLEYVENESKSPVIDHRETPEKHVKNVIDHIEHLLKEGTTADCIIDYSNGNIMVVDKLFIRGLTETLSNFSIHYKDNSYKLESETFQKFCIPVLQRYIDSNEDHQLECLYTLQLLVHGLEHPRGLLSELIGELYDAFVIQKESLCKWRDSKDQSAGKGVAVKSLNPFFNSLLNDDAN
Protein: Exosome complex exonuclease RRP6 (Rrp6p) (EC 3.1.13.-) (Ribosomal RNA-processing protein 6) (Q12149)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. RRP6 has 3'-5' exonuclease activity which is not modulated upon association with Exo-9 suggesting that the complex inner RNA-binding path is not used to access its active site.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:10465791, ECO:0000269|PubMed:10611239, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15489286}. Nucleus {ECO:0000269|PubMed:12923258}.
Interaction partners:
- Exosome complex component RRP42
- Exosome complex exonuclease DIS3
- Exosome complex component RRP4
- Exosome complex component CSL4
- Exosome complex component RRP40
- Exosome complex component RRP46
- ATP-dependent RNA helicase DOB1
- Superkiller protein 7
- Exosome complex component RRP45
- Exosome complex component SKI6
Sequence:
MTSENPDVLLSRVINVVRAASSLASQDVDFYKNLDRGFSKDLKSKADKLADMANEIILSIDEHHESFELKEEDISDLWNNFGNIMDNLLEMSDHSLDKLNCAINSKSRGSDLQYLGEFSGKNFSPTKRVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLRLVDDDENNPSHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMDIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIEKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRNIKNTNEEATPIPSSETKADGILLETISVPQIRDVMERFSVLCNSNISKSRAKPVTNSSILLGKILPREEHDIAYSKDGLPNKVKTEDIRIRAQNFKSALANLEDIIFEIEKPLVVPVKLEEIKTVDPASAPNHSPEIDNLDDLVVLKKKNIQKKQPAKEKGVTEKDAVDYSKIPNILSNKPGQNNRQQKKRRFDPSSSDSNGPRAAKKRRPAAKGKNLSFKR
Protein: A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-) (Q8WXS8)
Organism: Homo sapiens (Human)
Function: Has aminoprocollagen type I processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Sphingosine-1-phosphate lyase 1
Sequence:
MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGPAAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLRLRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRTDSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT
Protein: GH18 domain-containing protein (G8BHR2)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Secreted, cell wall {ECO:0000256|ARBA:ARBA00004191}.
Interaction partners:
- chitinase
- chitinase
Sequence:
MLLQSLFAVLATSAASALVAADNIALYWGQNVEGQQKRLSEYCENPDFEIVILSSITNFYTGFGDFDFNCYKNRTTLEMICHNFEEDIKHCQQKGKKVLLSLGAPTSVDPVGFDNTEDAVKLAENLWGRFGNGDGKEKPFGNALIDGFDLHITTGSDTGYVEFAEALRSKFDGSKNFLLTASPSCVFPNPQLGQVLSKVPLDYTFVQFYDSPCQTNKAFNFDTWSKFADSAPNPNMKSYLGLTTRGYTQSFIPPKDLPEFIKKVNCDSNFDGISLWDASGAWLKDIVGDWLINKNARYIDEIKYVLENETCPSPSSSTTASSSTEPSSSEEPTSSAEPTSSEEPTSSAEPTSSEESTSSAEPTSSEESTSSAEPTSSAEPTSSAEPSSSEEPTSSAEPSSSEEPTSSAEPSSSEEPTSSAEPTSSAEPSSSEEPTSSAEPTSSEESTSSTEPTSSAESSSSEEPTSSAEPSSSEEPTSSTEPTSSEEPTSSEEPTSSAESTSSTEPTSSTEPSSSQEQQNTDEASSEEPTTTPEADVSSSTLDSTTVITITSCHDDGCTQVPVTTGVTVITEEYTTYTTYCPLTTATTDETKHSSKDSIETKTDVGTTIVTITSCEENRCTPVAVTTGVITITENDTVYTTYCPLPTTKGDTSENVAPTTTTGAPGAPKSTIEKEEASRSKGEQGVHEVTAEKTTVTMGAEKTTGTTSAASGEETTVAGGAHEVPEETKTSTVVVASESKGTNTEESATTVATIAPVEVQSEESTEKASSTAAATEEVPVSTYEGKGVRSFAMENIMTIPLLCLALLF
Protein: Uncharacterized protein (Q57XQ8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Retrotransposon hot spot
Sequence:
MQASESGDHGDILPNGGHRSRHHRHKGKHPQHEETAALRVEGAESVDAEKAEREQVQEPPQQQQQEQEQQENKSDADSQNIGSVVEEFVSRLPAGDAVRATSEKARKLATEGKQLVKDVLENSNIRAVASGCVAKGKQVVDGARAYQHTAMEVAAKTVPHCRKPMEMCAATARSTVNSARSVAEKSTRCVAQTGGELRERAKSYVETMKSIRGKLFNFFEASKPRVAEVQRTGMKAVGERDLQLFVTALAQATACVVVLSRVITVEMCKVNRVNSTMRYIQGSTCMRLGASLWNCINPSLVQHVPVVGERVASAAAAFVAEVKQYTSDDRDDVQDEQKVAA