wanglab/gogpt-training-data huggingface dataset:
Protein: Metal cation efflux system protein CzcD (Cobalt-zinc-cadmium resistance protein CzcD) (P13512)
Organism: Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)
Function: Mediates a low-level metal ion resistance, probably by efflux of cations from the cytoplasm into the periplasm. Also mediates resistance to cobalt, cadmium and zinc via regulation of the Czc system. May repress expression of the Czc system by an export of the inducing cations. Binds and transports zinc. Can also bind cobalt, copper and nickel.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:10559151}; Multi-pass membrane protein {ECO:0000269|PubMed:10559151}.
Interaction partners:
Sequence:
MGAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYYRFEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGMFVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWALTSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFNASPALVGSKSLAAGGN
Protein: Oxysterol-binding protein (A0A140VJQ6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE
Protein: Noelin (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin) (O88998)
Organism: Mus musculus (Mouse)
Function: Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse. May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli.
Subcellular location: Secreted {ECO:0000269|PubMed:22923615, ECO:0000305|PubMed:22632720}. Synapse {ECO:0000305|PubMed:22632720}. Endoplasmic reticulum {ECO:0000269|PubMed:22923615}. Cell projection, axon {ECO:0000269|PubMed:22923615, ECO:0000269|PubMed:26107991}. Perikaryon {ECO:0000269|PubMed:22923615}.; SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum {ECO:0000269|PubMed:9473566, ECO:0000305|PubMed:25903135}.
Interaction partners:
- Glutamate receptor 1
- Noelin-2
- Glutamate receptor 4
- Neuritin
- Protein shisa-6
- Glutamate receptor 2
- Noelin-3
- von Willebrand factor C domain-containing protein 2-like
- Disks large homolog 4
- Glutamate receptor 3
Sequence:
MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTEAILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL
Protein: Colony stimulating factor 2 receptor subunit beta (A0A8I6GE59)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MDQHMAFIWGLCYMALVALCWRHGVTKAEETVPLKTLQCYNDYIERIICSWADTEDAQGLVNLTLYHWLDKKQPMSCELSEDLMWSECPSSHRCVPRRCVLPYTQFSVSKEDYYSLQPDRDLSIHLVVPLAQHGDKARPQNLQCFFDGIQSLNCSWEVWTKVTDSVSFGLFYSSSPKAGEKKCSPVVKELQASRYTRYHCSLNVSDPAAHSQYTVSVKRLEQGKFIESFNHIQMNPPTLNLTKNRDSYSLHWETQKMSYPFIQHAFQVQYKKKLDSWEDSKTENLNHAHSMDLPQLEPGTSYCARVRVKTIPEYKGLWSEWSNECTWTTDWVMPTLWIVLILVFLILTFLLALRFGCIYGCKLYRKWKEKIPNPSKSLLFQDGGKGLWPPGSTVTFSSKNPTPQGPQSNLFSELQGVSYTHLEDNEVSPLTIEDPNIIRDPSSGPDTTPAASSEPMEQSSNVQVDPPTLSGRPRKQLPSFDFNGPYLGPPQSHSLPDLPGQLVSPQGGGSLKPALPGSLEYMCLPPGGQVQLVPLSQVMGQGRDVDVQCGSSLETTESPSMESRESPPVELKEEEQEPRDNPVTLPISSGGPKDSKVASEYVTPADLVLTLPTEPLSTSLGPSLEVSSAQSPSLCLKLPRVPSESPALAPAVFEDYVELPPSMSQPAKSLPGNPAPPGPSSPAVSPGEPREEVGAAPTHPEGLLVLQQVGDYCFLPGLGPSPLSPPSKPPSPGLCLETEDLDKDLSVKKLPYQPIPQVPAIQFFKSLKHQDYLSLPPWDNSQPGKVC
Protein: Transcription initiation factor IIE subunit beta (O96881)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR016398}.
Interaction partners:
- General transcription factor IIE subunit 1
- CDK-activating kinase assembly factor MAT1
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIH subunit
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription factor IIH subunit 3
- General transcription factor IIF subunit 2
- Cyclin-H
- General transcription factor IIH subunit 4
- Transcription initiation factor IIB
Sequence:
MDPALLREREAFKKRAMATPTVEKKSKPDRPAPPPPSDDSRRKMRPPNAPRLDATTYKTMSGSSQYRFGVLAKIVKFMRTRHQDGDDHPLTIDEILDETNQLDIGQSVKNWLASEALHNNPKVEASPCGTKFSFKPVYKIKDGKTLMRLLKQHDLKGLGGILLDDVQESLPHCEKVLKNRSAEILFVVRPIDKKKILFYNDRTANFSVDDEFQKLWRSATVDAMDDAKIDEYLEKQGIRSMQDHGLKKAIPKRKKAANKKRQFKKPRDNEHLADVLEVYEDNTLTLKGVNPT
Protein: 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthase) (KDO-8-phosphate synthase) (KDO 8-P synthase) (KDOPS) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (P0A715)
Organism: Escherichia coli (strain K12)
Function: Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.
Subcellular location: Cytoplasm.
Interaction partners:
- 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
- Arabinose 5-phosphate isomerase KdsD
- 3-deoxy-manno-octulosonate cytidylyltransferase
- 3-deoxy-D-manno-octulosonic acid transferase
- Tetraacyldisaccharide 4'-kinase
- UDP-3-O-acyl-N-acetylglucosamine deacetylase
- Lipid-A-disaccharide synthase
- Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
- UDP-3-O-
- Arabinose 5-phosphate isomerase GutQ
Sequence:
MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
Protein: Protein FAM153A (Renal carcinoma antigen NY-REN-7) (Q9UHL3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVDKDTERDIEMKRQLRRLRELHLYSTWKKYQEAMKTSLGVPQCERDEGSLGKPLCPPEILSETLPGSVKKRVCFPSEDHLEEFIAEHLPEASNQSLLTVAHADAGTQTNGDLEDLEEHGPGQTVSEEATEVHTMEGDPDTLAEFLIRDVLQELSSYNGEEEDPEEVKTSLGVPQRGDLEDLEEHVPGQTVSEEATGVHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVHMMQVDPATLAKQLEDSTITGSHQQMSASPSSAPAEEATEKTKVEEEVKTRKPKKKTRKPSKKSRWNVLKCWDIFNIF
Protein: Poly-beta-1,6-N-acetyl-D-glucosamine synthase (PGA synthase) (Poly-beta-1,6-GlcNAc synthase) (EC 2.4.1.-) (Biofilm PGA synthesis protein PgaC) (N-acetylglucosaminyltransferase PgaC) (P75905)
Organism: Escherichia coli (strain K12)
Function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homomer poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- Biofilm PGA synthesis protein PgaD
- Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase
- Poly-beta-1,6-N-acetyl-D-glucosamine export protein
- Cyclic di-GMP-binding protein
Sequence:
MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIMWIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRYENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLVCIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIKRTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRALCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAFTCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLMIENRYEHNLTSSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG
Protein: Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase) (Q9NZL9)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. Can bind NADP (in vitro).
Interaction partners:
- S-adenosylmethionine synthase isoform type-2
- S-adenosylmethionine synthase isoform type-1
- Betaine--homocysteine S-methyltransferase 1
- Methionine synthase
- S-methylmethionine--homocysteine S-methyltransferase BHMT2
- Ubiquitin-like protein FUBI
- DNA
- DNA
- DNA
- Tyrosine aminotransferase
Sequence:
MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH
Protein: UPF0488 protein C8orf33 (Q9H7E9)
Organism: Homo sapiens (Human)
Interaction partners:
- Glutamate-rich WD repeat-containing protein 1
Sequence:
MAALGHLAGEAAAAPGPGTPCASRGARLPGPVSSARNPSTVCLCPEQPTCSNADSRAHPLGDEGGTASKKQKNKKKTRNRASVANGGEKASEKLAPEEVPLSAEAQAQQLAQELAWCVEQLELGLKRQKPTPKQKEQAIGAIRTLRSKRTPLPRKRQLMHSLFGDYRAQMEAEWREALRALRAAAYSAQVQPVDGATRKKSQRVCRPRSIWRAKATLDMPDEEFRFNFF
Protein: Homeobox ARX homolog alr-1 (Aristaless-related homeobox alr-1) (Q21836)
Organism: Caenorhabditis elegans
Function: Transcription factor (By similarity). Involved in activating or repressing transcription of genes in neurons. Regulates expression of nuclear hormone receptor odr-7 and LIM homeodomain protein lin-11 in AWA and ASG chemosensory neurons. In concert with lin-11 and forkhead domain protein unc-130 plays a role in specifying AWA and ASG cell fates. Plays a role in modulating dendritic morphology and functions of AWA neurons. Involved in regulating GABAergic motor neuron development, acting in parallel with nuclear hormone receptor unc-55. Required to maintain the functional and structural integrity of the amphid organs during larval development. Plays a role in anterior hypodermal morphogenesis. Required for touch sensation. May act as a transcriptional activator in touch receptor neurons (TRNs), forming a positive feedback loop with transcription factor mec-3, thereby restricting the variability of expression of target genes such as mec-3. Positively modulates expression of H3K4 demethylase rbr-2 in early embryogenesis and during larval development.
Subcellular location: Nucleus {ECO:0000269|PubMed:15790968}.
Interaction partners:
- Paired domain-containing protein
- Forkhead box protein pes-1
- Transcription factor unc-86
Sequence:
MPELKKEDSSKDEKDLDMNCPPLHRPNGADLNQYSKSLMEQLQAQLFANPALQFPSFPPAFSIAALTNNQHELKEDDGKKTPTGDNILEAASVLDNRENGSPSDGTNSPDDNGKRKQRRYRTTFSAFQLDELEKVFARTHYPDVFTREELATRVQLTEARVQVWFQNRRAKYRKQERSSTHHPYQAPMSIPNSNGDNPYQMMLSQEAIFAAINQQAAAHLLNEQVRIATSDRRSQSPSVPVTTSSPILPTSVTPTFQNADALNMLFGGITPVTQQLLYVQQFSRAMDAFRTQLLGSVPAGATAEVTDVVALKTEDSKSNSRAGSSSPTPTESSGAAATSTSPTNFADMNSLISDVKPKEESS
Protein: Keratinocyte proline-rich protein (hKPRP) (Q5T749)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Keratin, type II cytoskeletal 78
- Protein KPLCE
Sequence:
MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF
Protein: MoaB/Mog domain-containing protein (O53897)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Serine protease PepD
- Molybdopterin synthase catalytic subunit 2
- GTP 3',8-cyclase 2
- GTP 3',8-cyclase 1
- Cyclic pyranopterin monophosphate synthase 1
- Cyclic pyranopterin monophosphate synthase 2
- Cyclic pyranopterin monophosphate synthase 3
- Molybdopterin molybdenumtransferase 1
- Molybdopterin molybdenumtransferase 2
- Molybdopterin synthase catalytic subunit 1
Sequence:
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVSADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEAIRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLAAQIIGQLSSLEI
Protein: Cytolethal distending toxin CdtB (Q7VG76)
Organism: Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Interaction partners:
- Cytolethal distending toxin subunit A
- Cytolethal distending toxin CdtC
- DUF1561 domain-containing protein
- NAD
Sequence:
MRILLCFLMSFTFALANLEDYRVSTWNLQGSSANTESKWNISVRQLITGDNPANILMVQEAGAIPASARRTGRMVQPGGTPVEEFTWELGTYSRPNTVYIYYAPLDVGARRVNLAIVSDRRADEVLVVHQNVVATEASRPAIGIRIGNDVFFNIHALASGGGDAPALVTAVHDNFINMPQINWLIAGDFNRDPALLQSGLDTRIANHIRITAPNSATHFSSRGTNRTLDYAVVGRSSPSRSTIVLPQIAAILMAANIRAHLSSDHSPVHFGRF
Protein: CUB domain-containing protein 1 (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (Transmembrane and associated with src kinases) (CD antigen CD318) (Q9H5V8)
Organism: Homo sapiens (Human)
Function: May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Shedding may also lead to a soluble peptide.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Interaction partners:
- Proto-oncogene tyrosine-protein kinase Src
- Zinc finger and BTB domain-containing protein 7B
- Protein kinase C delta type
- Epidermal growth factor receptor
- T-cell differentiation antigen CD6
- Ephrin type-A receptor 2
Sequence:
MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIEPRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDHRYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSFSYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPYFKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQTGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLTPRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPKKFQKGRKDNDSHVYAVIEDTMVYGHLLQDSSGSFLQPEVDTYRPFQGTMGVCPPSPPTICSRAPTAKLATEEPPPRSPPESESEPYTFSHPNNGDVSSKDTDIPLLNTQEPMEPAE
Protein: Transcription initiation factor TFIID subunit 5 (TBP-associated transcription factor family member taf-5) (G5EF68)
Organism: Caenorhabditis elegans
Function: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (By similarity). TFIID recognizes and binds promoters via its subunit tbp-1, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (By similarity). The TFIID complex consists of tbp-1 and TBP-associated factors (TAFs), including taf-5 (By similarity). Essential for early embryonic development, but not required for transcription of some genes; probably acts via activating transcription initiation by RNA Pol II, as part of the TFIID complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:12458202}.
Interaction partners:
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 8
- TATA-box-binding protein
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 4
- Transcription initiation factor TFIID subunit 13
- PHD-type domain-containing protein
Sequence:
MDSENSSSHSISSPQMFQNTHNNSAMEDNLLSRPMNNESLQMIIGYLRRNGLTETEELLTREAGPVLRVEGSNGLPPEEAISVEFDTFVQHANDCTDVVQAEFSQLLFPIFAHSYIALIEKHAATARIFFNRFKIFIPECFSEFVYQLSLIEDAMTLRANEHVHILRENKFLVRLSRPTLKHLESIQTRVIGVKNIIAKHICIENADEVSTNRTTIETQMGGILGVTSKSDKRHKMMFSVLKDELMQNIEKRKTKGKDWKDMGKKMQTHCPQADRIPLPPISEHLREERRNWLRDVGKMAIISAESPVSICMYTTVNAPIGVASCDFTDDSSLIAMGLSDSSIVMNAMDPMNKMKKLRDMEFLDKIDIETADNVQSQMFDLQGSTTSVRYTGHGGPVFSVNFSPDRRLLISSAGDRTVRLWSMETQRNAVIYRTPAVVWQAQFCSRGYYFATASADKTAAMWSTDRMHPLRIFADPYGDVGCIDYHPNCNYIAGGSDDRYVRVWDVCSGTRVRIFSGHKASIIAVKFSPCGRYIVSLDAIGNLMIWDLAYQRLVAAEITEQAGTKGSITFSRDGGVFAVSHGNSSIQLYSLDTLIGTVLAAGQNDSYIEPKVNLDGFNIGSYATKETAVIGLHFTRRNLLLGFGCFGQ
Protein: Decarboxylase, Orn/Lys/Arg family (Q7D6Y7)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MNPNSVRPRRLHVSALAAVANPSYTRLDTWNLLDDACRHLAEVDLAGLDTTHDVARAKRLMDRIGAYERYWLYPGAQNLATFRAHLDSHSTVRLTEEVSLAVRLLSEYGDRTALFDTSASLAEQELVAQAKQQQFYTVLLADDSPATAPDSLAECLRQLRNPADEVQFELLVVASIEDAITAVALNGEIQAAIIRHDLPLRSRDRVPLMTTLLGTDGDEAVANETHDWVECAEWIRELRPHIDLYLLTDESIAAETQDEPDVYDRTFYRLNDVTDLHSTVLAGLRNRYATPFFDALRAYAAAPVGQFHALPVARGASIFNSKSLHDMGEFYGRNIFMAETSTTSGGLDSLLDPHGNIKTAMDKAAVTWNANQTYFVTNGTSTANKIVVQALTRPGDIVLIDRNCHKSHHYGLVLAGAYPMYLDAYPLPQYAIYGAVPLRTIKQALLDLEAAGQLHRVRMLLLTNCTFDGVVYNPRRVMEEVLAIKPDICFLWDEAWYAFATAVPWARQRTAMIAAERLEQMLSTAEYAEEYRNWCASMDGVDRSEWVDHRLLPDPNRARVRVYATHSTHKSLSALRQASMIHVRDQDFKALTRDAFGEAFLTHTSTSPNQQLLASLDLARRQVDIEGFELVRHVYNMALVFRHRVRKDRLISKWFRILDESDLVPDAFRSSTVSSYRQVRQGALADWNEAWRSDQFVLDPTRLTLFIGATGMNGYDFREKILMERFGIQINKTSINSVLLIFTIGVTWSSVHYLLDVLRRVAIDLDRSQKAASGADLALHRRHVEEITQDLPHLPDFSEFDLAFRPDDASSFGDMRSAFYAGYEEADREYVQIGLAGRRLAEGKTLVSTTFVVPYPPGFPVLVPGQLVSKEIIYFLAQLDVKEIHGYNPDLGLSVFTQAALARMEAARNAVATVGAALPAFEVPRDASALNGTVNGDSVLQGVAEDA
Protein: Ceramide transporter 1 (A0A2R8YE18)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
Sequence:
MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFSSVGTHRFVQKVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANGLLGCKPHISRKYPKLKTDRRTDGQTDG
Protein: Uncharacterized protein (Q5AX78)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Kinetochore protein
- PHD transcription factor
- PHD finger domain protein, putative
- ATP synthase subunit beta
- Histone H2B
- Histone H2A
Sequence:
MKLFNTLSLLLGAAATTVFAGRQDGKNPDTFYLKTSGAENSAHNDLYVYGYHAGAGINDAVLTPDIETASRAYLNGTKVLFDYNTTFPWGLSPWGVTNYAAWQFVQINAGTGQDGFSVNSTGLQWSQQKGFGGWLVCDWWHNAPQLFYLYRYYDAEYPASCSEVKLVTEPTA
Protein: Transaldolase (EC 2.2.1.2) (20 kDa phosphoprotein OrfU) (CSI9) (P19669)
Organism: Bacillus subtilis (strain 168)
Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Does not show fructose-6-P aldolase activity.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Transketolase
- Probable fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase 1
- Glucose-6-phosphate 1-dehydrogenase
- Fructose-1,6-bisphosphatase class 2
- Triosephosphate isomerase
- Pyruvate kinase
- Enolase
- ATP-dependent 6-phosphofructokinase
Sequence:
MLFFVDTANIDEIREANELGILAGVTTNPSLVAKEANVSFHDRLREITDVVKGSVSAEVISLKAEEMIEEGKELAKIAPNITVKIPMTSDGLKAVRALTDLGIKTNVTLIFNANQALLAARAGATYVSPFLGRLDDIGHNGLDLISEVKQIFDIHGLDTQIIAASIRHPQHVTEAALRGAHIGTMPLKVIHALTKHPLTDKGIEQFLADWNK
Protein: C-C chemokine receptor-like 2 (Chemokine receptor CCR11) (G-protein coupled beta chemokine receptor) (Lipopolysaccharide-inducible C-C chemokine receptor) (L-CCR) (O35457)
Organism: Mus musculus (Mouse)
Function: Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptor. Plays a critical role for the development of Th2 responses (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Retinoic acid receptor responder protein 2
- C-C motif chemokine 19
- C-C motif chemokine 5
- C-C motif chemokine 2
- Nicotinamide phosphoribosyltransferase
- C-C motif chemokine
- C-C motif chemokine 7
- C-C motif chemokine 3
Sequence:
MDNYTVAPDDEYDVLILDDYLDNSGPDQVPAPEFLSPQQVLQFCCAVFAVGLLDNVLAVFILVKYKGLKNLGNIYFLNLALSNLCFLLPLPFWAHTAAHGESPGNGTCKVLVGLHSSGLYSEVFSNILLLVQGYRVFSQGRLASIFTTVSCGIVACILAWAMATALSLPESVFYEPRMERQKHKCAFGKPHFLPIEAPLWKYVLTSKMIILVLAFPLLVFIICCRQLRRRQSFRERQYDLHKPALVITGVFLLMWAPYNTVLFLSAFQEHLSLQDEKSSYHLDASVQVTQLVATTHCCVNPLLYLLLDRKAFMRYLRSLFPRCNDIPYQSSGGYQQAPPREGHGRPIELYSNLHQRQDII
Protein: Altronate oxidoreductase (EC 1.1.1.58) (Tagaturonate dehydrogenase) (Tagaturonate reductase) (P0A6L7)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Altronate dehydratase
- Uronate isomerase
- Mannonate dehydratase
- PTS system mannitol-specific EIICBA component
- Hexuronate transporter
- 2-dehydro-3-deoxygluconokinase
- 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
- Exu regulon transcriptional regulator
- Galactarate dehydratase
- KHG/KDPG aldolase
Sequence:
MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC