wanglab/gogpt-training-data huggingface dataset:
Protein: hydroxymethylglutaryl-CoA reductase (NADPH) (EC 1.1.1.34) (A0A060XV16)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Peroxisome membrane {ECO:0000256|ARBA:ARBA00004585}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004585}.
Interaction partners:
- Hydroxymethylglutaryl-CoA synthase
- Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain-containing protein
- Mevalonate kinase
- Mevalonate kinase
- UbiA prenyltransferase domain-containing protein 1
- UbiA prenyltransferase domain-containing protein 1
- Diphosphomevalonate decarboxylase
- Diphosphomevalonate decarboxylase
- Squalene monooxygenase
- Squalene monooxygenase
Sequence:
MLTGLFRMHGMLVASHPWEVIVGTVTLTICMMSMNMFTGNAQICGWNYDCPKMEELVLSSDIIILTITRCIAIVYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSKACALAKYALSSNSQDEVRDNIARGMAVLGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLESLGLVMVHAHSRWIADPLSLNSNLDVSQVSSMSLDNHLPKRIDPERPLWQFYMSRLVSMDIEQVICLGLALLLAVKYIFFEQVELESTLSLKSPLSQGPDRAPRWSADQCCRKEVAPPHPPKSPLRTATPTPPALAEATKEERAEVIRPLPAPTTEPQPTFRLGSMEEERESQAECPRAEPSQPSLPSDPRPLEECLTILKNPEMGARFLSDDEVVVLVNSKHIPSYKLEAMMERPERGVSIRRHMISSKLPNSSALSSLPYLDYDYSKVMGTCCENVIGYMPIPVGVAGPLHLDGKQFQVPMATTEGCLVASTNRGCRAISLGGGASSRILADGMTRGPVIRCPSACLAAEVKGWLESTDGFQAIKDAFDHTSRFARLQKLMIGLAGRNLYIRFQSRTGDAMGMNMISKVCVRVYCERMCVLDM
Protein: Transcription factor with AP2 domain(S) (O96201)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MNTHKNNDRFDEYSLNNNSNLNAYVNMSNEAHNNFLVNRRNDMNYEMYNSINSGHMSNINNNTNNLQDAYINKELHYMNSDKINIAKNHQNVHMTATYNNMDKNNANNNIIHLNNHINMTDDQNYFYNSTTNNKMNNTLKENNFNNNMNTVNNSFYHNTDNNFLNFTRNQNEQDTYVNNNIINNFNNQNVDKNINNNNNNPNKNVESINKFNHIYNMQNFNHFIPNISNGKNGNLENNASLSHNVNSVSTISELHNFNYMNNMDLNNVDMNNMNMNNMNMNNMNMNNMNMNNMDMNNVNMNNMNMNNMDVNSMNMNNMDNMNNMNMNNMDVNNMNMNNMDVNNMDNMNNMDNMNNMKNLSNFNNSYQYNSIPQFNSSSRFNNITHFNNGISHNVNNVSNFSNNAHLDNSNNMNRLNAVNNFGDINSFHDPLNEMQVLNKNVNMQNENHFNVMNDEMKNYNNVKRINSISHIPYMNNLKNYNEHTSMVKGKGNTNRKKSNNLKINNNPGSVNARAISENNQSTAHGNIPMGSVDKVIKHDRMDNDLKNINNMNNMNSMNNMNSMNNMNNMINMNNMNNMNNMINMNNMNNMNNMNNMSNMNNTSILNNNNKKITKRGRAKKNSTININNINKMNSTNNKSSMINMNSVNNMNSVNNMNSVKNMNSVNNMNSVNNINNVNNINNVNNINNVNNINNVNNINNVNNINNVNNINNVNNMNNMFNVNPQLNIMGIMKDINNNNITVSNKNKLMNNYINDNNIMNMEGSINETYNFDGTLNNKNVSNNNNNDIHDKGVLNTLNRSKSSSYIKPHRNLTLPINMYMNNTYMYNSKAYVNYENQNWMAQQDCNDKNGLSLNEGPRYNDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNHSIINNNITQGIHRGSMINNQHFDELSYNPNGIFLEKNTITNYNEMLGSGYNNMYDKNAVKGNMNLIGKHSNYDLMKNGNMINGYKLNMQEVQKGMNEVGKKRAPRRRAKTINLKSINRFNTVSLGLKGNHNMENMNNMDNMDNMNNMINVSNVNNVNNMNNVNNVNNMNNVNNMNNVNNMNNVNSVNNMNNTNNMNNMNNVNSVNNMNNTNNMNNMNNTNNMNNMNRMNHIDNNMVTNLNYMDNKINNAGNNLNGEFSKRILYNRSKSTENIKEMMQPHNEANNISGNNTSDSNNITLNKNLVEMILRNNKPSIDKNIHESVNRSYTSFLMNIGSSYLKKKKTAEIKTGENNTENNKGIVNVNSQVEEKGKSENKSILEIKKEGQIKNVIYNNNNNNNEKDQNADQYQDQNKNHKQDQRQDQNKSHKQDQLHDQNQNQGQLHDQNQNQGQLHDQNQNQGQLHDQNINQGQLQNQNQNYYQNYYQNHYQNDHQNDHQNDHQNDHQNHYQNNHQNDHQNDHQNDHQNDHQNHYPYQYQDQGVSKEINNKEIEENINKLNEESDENNNLEILDEEEITNKSVISNTMNMVELKNENKNEMMINDIKKEEEISAQIVEPVKKRGRKKGSKFVHKNITNEHILSQLKEPKRKGRKRKIWIQPLDNYNKVEDNKLKEYTNNIDIRDDNKANTQNEDVTTNNVTTLCCNKKAKYESMNPNSIRNMFILLRNKLSNLNVKNTMNSHSEINMLINNFIYILKIMNKHKQMLENIYTINFTNIDDICVRNYLEKHFPFIKGYRNKYEITDDLFMQGNDDNHLSKDINCINGNEDIGLNASCEQNEENENHEKSDMYNYKNDNSITNMEKSPNNITLVHKNIKDEDNFETIFLKTRSSFSSVDSNIIHIDNTQNFKLSNSSENKLNQFEKKTVLLSNDILYDAKKEIEQSYMNSQEKEKNYLH
Protein: RSC chromatin remodeling complex ATPase subunit (A0A1D8PJG4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Chromatin structure-remodeling complex protein RSC8
- Chromatin structure-remodeling complex protein RSC58
- Uncharacterized protein
- Bromo domain-containing protein
- Uncharacterized protein
- Arp9p
- Chromatin structure-remodeling complex subunit SFH1
- Chromatin structure-remodeling complex subunit RSC1
- Npl6p
- Actin-related protein 4
Sequence:
MNGSAIANGNGSVGVTPALSQVQLQPGSANLTTQSNDSVVPKNKEELNELLSKYYKLLFDSNKLKKEFEKSEDKSEGKFEDVNAQAKLDIESVLAQVSKEHEEYIKDESEFMQELFSENLKGTIKSEGFDNELFEKQVAGLLLLSRDYDLPEKFQKEFTTISDQTKKDDLVNEILEKLTELETDFETRAQNLGIKVPSPSSSSSSKTDKDTLHSPLGTIHAEKIISNKISQRLKELENLPANIGTFGDTDGIDKFKIQALIELKALRLLGKQKLLRHNILVHEAQQVKYADPNLKSLPLALSEKRSFNVRPKIEQRNPQLLAVQLEELKKLEAREAKRKQHIEKVDLVVEKSTSRSEAKYVRDHYRSHYLVRQINNFHQTTEKEESKKLERTAKQRLQALRSNDEEAYLKLLDKTKDHRITHLLKQTNQFLDSLTEKVRAQQEEASGGSMGTPRHGSPEVAVENKSDDKAELREKTDYYEVAHRIKEKITEQPTILVGGKLKEYQMKGLEWMVSLYNNHLNGILADEMGLGKTIQSISLVTYLIEKKHENKFLIIVPLSTITNWTLEFEKWAPSIKVIVYKGSQQQRRSLQPDIRYGNFQVLLTTYEYVIRERPMLAKFHYSHMIIDEGHRMKNAQSKLSQTLRTYYKTKNRLILTGTPLQNNLPELWALLNFVLPGIFNSVKSFDDWFNTPFANTGAQEKIELTEEESLLVIRRLHKVLRPFLLRRLKKDVEKDLPDKVEKVLKCNLSGLQYVLYQQMLKHNALFVGADVGGAKSGIKGLNNKIMQLRKICNHPFVFEEVESVLNSSRLTNDLIWRVSGKFELLDRVLPKFKKSGHRVLMFFQMTQIMDIMEDFLRWKDMKYLRLDGSTKAEERQDMLKVFNAPDSDYFCFLLSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITNDSVEEVILERAHQKLDIDGKVIQAGKFDNKSTAEEQEAFLKRLLEADANGADNEENDSLDDDELNEILARSEEEKVLFASMDEERKSEKVPYKSRLIEKDELPAVFTEDISHHFEKKEKELSKMRDKKRVRYDDGLSEEQWLKAMDDDNDTVEEAIKRKEERIAKRKRNKAIREGLLEEDIKDDEVGEEDDEDFEEAAQPRKRQRRARTPLPHIDNDDISGDSGNGGGAAIELDVDDDDDNEPETDGFTSKCLSVIDEITALTDETDGHNLSDIFIKLPSRKLYPDYYSIIKKPVSINQVKKQLDQEKFASFEDFIAELKQMCLNAKTYNQEGSFVHTDATVIEKLLDEKLANQE
Protein: Protein COS7 (Q07788)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Putative uncharacterized protein YDL247W-A
- Putative uncharacterized membrane protein YAL059C-A
- Putative uncharacterized protein YAL056C-A
Sequence:
MKENEVKDEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIYKSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQLIQFCKEITENTPSSDPHDWEVVVANLNSYLYENKAWNTKNFFFNATDCEKMFRTTVLEPFSLKKDKAAKVKSFKDSVPYIEEALQVYATGFDKQWKLFITEKSWSPVGLEDVQLPKDIHRSKLTWFLKRIFTIYSLPLWLAFLNCICVSQHFCLAFRILCPGLFFLMMVWLFQNMRTTALLVKMEHKMQFLLTIINEQESGANGWDEIARKMNRYLFEKKAWKNEEFFFDGIDCEWFFSHFFYRLLSAKKSMWLLPLNVELWPYIKEAQLSRNEESLMKK
Protein: MatA protein (Q54HW9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Cell fusion related protein
- Sepiapterin reductase
- ATPase subunit 8
- ATPase subunit 4
- DNA topoisomerase 2, mitochondrial
- Gamete and mating-type specific protein A
Sequence:
MDPLDKIINDIKKEANDSGVTLAPLSVPKPKLEELSEQQKIILAEYIAEVGLQNITAITLSKKLNITVEKAKNYIKNSNRLGRTNNLKTIGILQEEVSSMEAKSMTW
Protein: Uncharacterized PPE family protein PPE29 (P9WI09)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Could be required for host endothelial-cell invasion and/or intracellular survival.
Interaction partners:
- Uncharacterized PPE family protein PPE30
Sequence:
MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD
Protein: Steroid C26-monooxygenase (EC 1.14.15.29) (Cholest-4-en-3-one 26-monooxygenase) (Cholest-4-en-3-one C26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]) (Cholesterol C26-monooxygenase) (Cholesterol C26-monooxygenase [(25S)-3beta-hydroxycholest-5-en-26-oate forming]) (Cytochrome P450 125) (Steroid C27-monooxygenase) (P9WPP1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain during infection. Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25S)-26-hydroxycholest-4-en-3-one (alcohol), (25S)-26-oxocholest-4-en-3-one (aldehyde), to finally yield the carboxylic acid (25S)-3-oxocholest-4-en-26-oate. Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one.
Interaction partners:
- Acyl-CoA dehydrogenase FadE28
- Acyl-CoA dehydrogenase FadE29
- 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA lyase
- 3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase beta subunit
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
- Polyketide synthase Pks13
- Steroid C26-monooxygenase-3-oxocholest-4-en-26-oate forming])
- Cholesterol oxidase
- Steroid 3-ketoacyl-CoA thiolase
- 3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component
Sequence:
MSWNHQSVEIAVRRTTVPSPNLPPGFDFTDPAIYAERLPVAEFAELRSAAPIWWNGQDPGKGGGFHDGGFWAITKLNDVKEISRHSDVFSSYENGVIPRFKNDIAREDIEVQRFVMLNMDAPHHTRLRKIISRGFTPRAVGRLHDELQERAQKIAAEAAAAGSGDFVEQVSCELPLQAIAGLLGVPQEDRGKLFHWSNEMTGNEDPEYAHIDPKASSAELIGYAMKMAEEKAKNPADDIVTQLIQADIDGEKLSDDEFGFFVVMLAVAGNETTRNSITQGMMAFAEHPDQWELYKKVRPETAADEIVRWATPVTAFQRTALRDYELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNILRNPNPHVGFGGTGAHYCIGANLARMTINLIFNAVADHMPDLKPISAPERLRSGWLNGIKHWQVDYTGRCPVAH
Protein: Putative tail-fiber protein (H9C1B7)
Organism: Pectobacterium phage ZF40 (Bacteriophage ZF40)
Interaction partners:
Sequence:
MDQKFFRVPFAQSGDRQTIPDATQTSGAVSFPSGWGGDYAKDPAVDANAKPVEREAMNAILYAITNAVRQYQTFGFPEYITPADNNGGAFSYSSGAVVRYRAAADQPFKSYVSIADNNTSVPGSDETKWQEFIYREATTQEITEGTSGTTVVSPRRLKERTDIIDGEIDEINDSLTRVGNLQVAQVSIDAQGSVVLNAPTDCVQILIIGHYTADAVESRDYWESKLSVNGAVVDTTPFYGYVTGSRGHGHHRRELLPFSQLVDMQLTAGDAINFEYSSNRGSSTTFTVFYIQGVSTDKPDHPTAIIISPGSSTINAGGQQQLTATVLPANVAADYPVTWSVSDPALGSVDSNGLYTANSGASGTQSVIASVSTGLASTATITQHVYLTNIDIGNPPANLIADRTYTVPITYSPSNYTEPVQTSSSDSTIATLSIDGTLTISSGGTATLTLTGASSGVTDSITITATEEVVPERYLQIAERLSEISTAGSAAQAAARSNLGLGGLATKDSLTAADVGAVPQASASLGTENLNTVTSPGRKFQSLTSNATLARNYPVALAGMLDVIRTTDEGIRQTFYPYNTTEVYHRYCVDVGANPIVFSTWAKSGGDYLEKSQNLQDVSDKPLARDNMGVGYTISTSEPPASAAGYAAGHIWYQV
Protein: Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Peroxisomal fatty acyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain] (Q9R0H0)
Organism: Mus musculus (Mouse)
Function: Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)).
Subcellular location: Peroxisome {ECO:0000250|UniProtKB:P07872}.
Interaction partners:
- Peroxisomal bifunctional enzyme
- 3-ketoacyl-CoA thiolase A, peroxisomal
- Peroxisomal multifunctional enzyme type 2
- Sterol carrier protein 2
- 3-ketoacyl-CoA thiolase B, peroxisomal
- Trifunctional enzyme subunit beta, mitochondrial
- Enoyl-CoA hydratase, mitochondrial
- Carnitine O-palmitoyltransferase 2, mitochondrial
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Long-chain specific acyl-CoA dehydrogenase, mitochondrial
Sequence:
MNPDLRKERAAATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREFGIADPEEIMWFKKLHMVNFVEPVGLNYSMFIPTLLNQGTTAQQEKWMHPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITRGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGSAAQSLSKACTIAIRYSAVRRQSEIKRSEPEPQILDFQTQQYKLFPLLATAYAFHFLGRYIKETYMRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVQSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTLVDINSLDSLTEAYKLRAARLVEIAAKNLQAQVSHRKSKEVAWNLTSVDLVRASEAHCHYVTVKVFADKLPKIQDRAVQAVLRNLCLLYSLYGISQKGGDFLEGNIITGAQMSQVNSRILELLTVTRPNAVALVDAFDFKDVTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYYKHLKPLQSKL
Protein: Thymidine kinase (EC 2.7.1.21) (P23331)
Organism: Escherichia coli (strain K12)
Function: Phosphorylates both thymidine and deoxyuridine.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00124}.
Interaction partners:
- Thymidylate synthase
- Thymidine phosphorylase
- Thymidylate kinase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- Purine nucleoside phosphorylase DeoD-type
- Uridine phosphorylase
- Cytidine deaminase
- Protein UshA
- Pyrimidine 5'-nucleotidase YjjG
- 5'-deoxynucleotidase YfbR
Sequence:
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQVYELSEVVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQAGRPYNEGEQVVIGGNERYVSVCRKHYKEALQVDSLTAIQERHRHD
Protein: Motile sperm domain-containing protein 3 (O75425)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MRRGAPQDQELVGPGPPGRGSRGAPPPLGPVVPVLVFPPDLVFRADQRSGPRQLLTLYNPTGTALRFRVLCTAPAKYTVFDAEGYVKPQSCIDIVIRHVAPIPSHYDVQDRFRIELSEEGAEGRVVGRKDITSILRAPAYPLELQGQPDPAPRPGPPAGTPPPTARHFQEHPRQQLATSSFLLFLLTGIVSVAFLLLPLPDELGSQLPQVLHVSLGQKLVAAYVLGLLTMVFLRT
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (E9QFU7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MVDKVHLLPYFFGNITREESEVYLQQGGSGDGLYLLRQSRSFLGGYALSLSYGRQFYHYTIERELNDTYAIAGGKSHRTPIDVINYHSQESDGLICLLKKPFHRPRGTEPKVGPFEDLKEQLIRQYVEQTWNLKGSALDQAIISQRPQLEKLIATTAHEKMPWFHGKIDREDSELRLLNTSRVNGKFLIRQRENSGRNESYALCLLHNNQVMHYRIDKDRAGKLSIPDGKKFDTLWQLVEHYSYKPDGLLRVLTETCPRPSHHSEGSAENPYKITPNGKDDYSKQGNFLDSAMPMDTQVYESPYADPDELRSTKVNRSDLTLEDGELGSGNFGTVLRGVYQMKKTQKVVAVKILKNDDDNAAVKDEMLREANVMQQLDNPYIVRMIGICEAENLMLVMELAELGPLHKFLQKNKHITVKNLTELVHQVSMGMKYLEEHNFVHRDLAARNVLLVTQHYAKISDFGLSKALTEDENYYKAKGHGKWPLKWYAPECMNYLKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGNEVIQMIENGQRMSAPPDCPPEMYDLMKKCWTYKPDERPGFSVVEPRLRHYYYDISQ
Protein: Protein kinase, putative (EC 2.7.1.-) (Q57VI9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Serine/threonine-protein kinase, putative
- Protein kinase, putative
- Trichohyalin, putative
- non-specific serine/threonine protein kinase
- Crossover junction endonuclease MUS81
- DNA replication licensing factor MCM4
- non-specific serine/threonine protein kinase
- Phosphatidylinositol 3-kinase catalytic subunit, putative
- non-specific serine/threonine protein kinase
- Protein kinase, putative
Sequence:
MDFHSLQSTLTEARALASSSKTVSFDHHYELLEELGKGAYGTVWKCCRRHDSLKRPYGVKIINKREAGAKGLRSVMGEVETMSLLSHPNIVRLEETFHDDQTLWIVMEYMAGGELQRALKRDGSFSEVQTRRITMQLLFALEFIHQKGIVHRDLKPENCLLSEGDLVCKISDFGFAVLVGVDQCLMSFCGTTVFMAPEIFSDTNYGKPVDMWALGVMVYLMFTGEYPFLGRTQKETTEAILKANYNMKDGKISEGSSALHDFISKLLVVDPNRRYSAREALKHPWIKLGMNMEIPDDEPKAPKRSGLRPRGVFRALSIAIMAAHRLLYLRYCRMLDSSDCGNCAMLRNFTYVVSGRYEPPCPSLECSGVFLRHPRGLPLLLPMVEVSRTLESLDLSNNNIFNLTFLQQLVKVVGNHPSLVSLNLSNNPIPALAGRGLLRLARSPQSRLTYLGLEGTQLSAEALAQISSALKERLAAAPTLCLSMQSCTGPRPLEQVSPTQSRSARTTRSRSQHGSAHTSLMNPSRSPQSKGPRLPPINSKRRNER
Protein: Cytokinin dehydrogenase 3 (EC 1.5.99.12) (Cytokinin oxidase 3) (AtCKX3) (CKO 3) (Q9LTS3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group. Catalyzes in vitro the oxidation of various types of cytokinin nucleotides that are known as direct products of cytokinin biosynthesis. In association with CKX5 regulates the activity of the reproductive meristems, flower organ size and ovule formation.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:14555694}. Vacuole {ECO:0000269|PubMed:14555694}.
Interaction partners:
- Histidine kinase 3
- Adenylate isopentenyltransferase 7, mitochondrial
- Histidine kinase 2
- Adenylate isopentenyltransferase 1, chloroplastic
- Adenylate isopentenyltransferase 5, chloroplastic
- Adenylate isopentenyltransferase 4
- Adenylate isopentenyltransferase 3, chloroplastic
- Histidine kinase 4
- Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG1
- Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG3
Sequence:
MASYNLRSQVRLIAITIVIIITLSTPITTNTSPQPWNILSHNEFAGKLTSSSSSVESAATDFGHVTKIFPSAVLIPSSVEDITDLIKLSFDSQLSFPLAARGHGHSHRGQASAKDGVVVNMRSMVNRDRGIKVSRTCLYVDVDAAWLWIEVLNKTLELGLTPVSWTDYLYLTVGGTLSNGGISGQTFRYGPQITNVLEMDVITGKGEIATCSKDMNSDLFFAVLGGLGQFGIITRARIKLEVAPKRAKWLRFLYIDFSEFTRDQERVISKTDGVDFLEGSIMVDHGPPDNWRSTYYPPSDHLRIASMVKRHRVIYCLEVVKYYDETSQYTVNEEMEELSDSLNHVRGFMYEKDVTYMDFLNRVRTGELNLKSKGQWDVPHPWLNLFVPKTQISKFDDGVFKGIILRNNITSGPVLVYPMNRNKWNDRMSAAIPEEDVFYAVGFLRSAGFDNWEAFDQENMEILKFCEDANMGVIQYLPYHSSQEGWVRHFGPRWNIFVERKYKYDPKMILSPGQNIFQKINSS
Protein: CUB-like domain-containing protein (Q9XUH7)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MPSLTTFLSVALLASVVSAVGNTCKTGNVVHKPVIDGTPVYFPATWREDKAAPALAKDQSCSWMVTIPQGYYAKLTISGKMGDKHSYFQTVDCTGNVVQTKLETKHPYYFPSPKFTLVVSNEAAATFAFKIEWAPYTTQISYIAGIGMQPHVLNITQDLFAADFSSDKVALFVSPADPNDYYSLRSSLVFEGQDYNGNFVANLYTLYETHQQWVSKGSMVYIVNLEASNKTDILLVQDIQYANFVDYVELNCYGVSTCSASVDGGDGKSAVLSLYASRSNETLVDIKMDPSATMKVYYGSETAFGFDSTYNGSTINSQLPLTFYGEDVTQYVISNGKATLTFNIPQ
Protein: MIP08660p (Q9VVH8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTKGVRICNDGLPGLPNERPYSRRTLDTRQKTQKMSSRPSRKPLQSLQTVGRNTSSSLKRIGSPISEEEFGVLVQQDCKAEQHHTDRQNLADIILMQARRIEKQQREMKRIKAHYERQVSTIKNNAIMLESHLQKVLASVERDRAKRIGHHCQDMLGAVEKLQRSDIQVKPQSSANQLLIQYLHSKKISHSTKKSNENTSRYRNML
Protein: ATP-dependent protease ClpE (Q8DVD0)
Organism: Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Interaction partners:
- ATP-dependent Clp protease proteolytic subunit
- Chaperone protein DnaK
- ATP-dependent Clp protease ATP-binding subunit ClpX
- Co-chaperonin GroES
- Chaperonin GroEL
- Transcriptional regulator CtsR
- Adapter protein MecA
- Protein GrpE
- Heat-inducible transcription repressor HrcA
- Chaperone protein DnaJ
Sequence:
MLCQNCKLNEATIHLYANVNGQQKQIDLCQNCYQIMKTDPENGPLNHLSQQNSSSINPFFDDFFGDLNNFRAFNNQDLPNTPPTQAGGGNGNGGNNRRPGGPQQQASQKPNGLLEEFGINLTDIARKGEIDPVIGRDEEITRVIEILNRRTKNNPVLIGEPGVGKTAVVEGLAQKIVDGDVPQKLHGKNVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVAETITILKGIQPKYEDYHHVKYTDEAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDHRLIEAENLKAQATRDEDYEKAAYFRDQIAKYKEMQSAKLDKENTPVITEKNIEVIVEQKTNIPVGELKEKEQSQLIHLADDLKTRVIGQDAAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSEDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEANVGFGASREGRTNSVLGELGNFFSPEFMNRFDGIIEFQALSKDNLLQIVSLMLDDVNQRLAVNAIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDFYLEHPEQKELKAIMTSNGKIVIKASNKVETVTKATSD
Protein: Serine/threonine-protein kinase pakE (EC 2.7.11.1) (Q54B33)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May play a role in responding to changes in chemoattractant levels.
Interaction partners:
Sequence:
MEEDKDSDTLQILNDIINNEPNLEIYVKSKNNNYISSRELPTQDSSTKTSNITTPNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTPTSLNSSWKSVVPKRKIDTSSGAILNNNNNVGSPNNQSTSQTNHQQPPPQQLQQQQSLSSTSTPSISPPMLSPSRRNVTSPNLTRSDPTVPITNSRPTSPLTPPLSPQFQLNNLNFDDNNDHSTTTTNNNNNNNNNNSNNNNNNNRPKLMRENSINKRSSLQTLPVSSSSSSSAEDEILIKVWLPMEYTGQLYKVRKFSGGSSTLKVSSMLNSQLSPMYQSPKNKLFLNNEEKPIPSHLTLKDLSLSKYDILYLRREPEYELIIPSSPQCGSLVMDKDIKIDDMLIKIEHWLKDILDHAPHSTSQQQQQQLQQQPILHVDKHEYFTSLEDQQLMSGHITNSSQYTLLKKLSVPTSNSRQTGKMSRGYYLRLYDQKPISNYGIKIKDTLIFKKKILNRGLSIDDAEGGIEITVLYSPLSMLPTTSDLDFEKELKENQQQLNNNNNNNNNNNNNNNNNNNNNNNNITTTTTTTTSSLINQTNEILLPNLIKIDNTSLLQDIKNEKKKRKSKRTPSSVGLPFNIIHKTHVDFEYKWSGTSVEDTFEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPTRIKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVILKAPYNSKADIWSLGITLIELAEGRPPNRGLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFIKNAKTTEVLSNLVKQTLSSRQSI
Protein: Myosin VI (A0A590UK22)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISI
Protein: T. brucei spp.-specific protein (Q57W96)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRMDDNFGVSGTAQKEVNWMEGPKKSSSICGKPSEHLFFLVCACYLFTASLLCVTWTRLYTDMRAYVCIINSLSLLIFPVASLFSLYVTGFFILEVGLFLSFSLDFFYRPLPWPVEDVQISNNSGELVACVCLNGGHRYLTHTENNCAVVAVLLVTLK
Protein: FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (FKBP22) (PPIase) (EC 5.2.1.8) (Rotamase) (P0A9L3)
Organism: Escherichia coli (strain K12)
Function: PPIases accelerate the folding of proteins (Probable). Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Displays a preference for substrates with a lysyl residue in the P1 position.
Subcellular location: Cytoplasm. Periplasm {ECO:0000269|PubMed:7610040, ECO:0000269|PubMed:8703024}.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase B
- Chaperone protein HtpG
- FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase
- Peptidyl-prolyl cis-trans isomerase C
Sequence:
MTTPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIADALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTESGLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIEALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL
Protein: Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform F (EC 2.7.1.68) (A0A0B4K7E3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASGDGDTINTIDMDSSSASQAKLAEPSNASTDHVGNSSPDLGNRPNRASSKADKERKIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAESEPIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNHRKFRTLVTSYIALKHSPSKRKSLSKAIQRSIDSDNEVASRPVHASHSHSSGKIHQPAKPPTTEPTPAGAAGGAERGATALGPATTSGASERAPPPVKQRTPAASNLKTRVPPPVPPRGSPRRKDAQDRTTPGTTPSCSSTPPPAFDDISEDSSNKNSSSSIGRRSHHHHHHHQQSQQHQQSYYLDRKMNIGPAYRGSYKEDIVSVSEVHLDTLLAVDTSSSSQYGSRGGLAWTPPASGEGSTPTWTEGTPSFTDSSSSGDLDNFSPINSSKIDRHKPTVEEAINSLSAGMIN
Protein: Folate transporter, putative (Q580Y2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- JAB1/MPN/MOV34 metalloenzyme domain-containing protein
Sequence:
MTTSPNACQDQPPQHSAPQAHEAECTTHKLSAEETMDARPVHPDARALFRKLPCVWSIPVLGTAVEAFGPKFVFALGFCELFGKGIADNIIRSSLFPMFTYTFGADAKLYQLMGGMSSLGYAVKPFAAMFSDLFALFGYTKRWYLALSCVVGSTLAIVYGSLPGELSYVPVAGFLVFVITFTVANLDILTQGHYSRLIRRVPLAGPSLVSWVWWCLLVGSLVASSIVGPLTDKRLQRVAVFISAGMQLVPTIFFILNWYGERKNREERAYDLKIIREKKLEHEADAVRLQGSEATSGSLDNPSDTEEVGEGGARILPCCCGAFEVNREVFARNKKVVFYCMLLTLGAIGMVLVTVLGTRLQLLITSVVASFTLCGLGFVALPLVIAKANMFTFISRVTYIQLRGAMDNVFMATPDCFPGGPNFSYFYYNTVGNVIGTMGGVIGVTLFRYVFSKRSYRLTFIVTTLIEIVSSIFDIIIVERWNRPYVSDHVVFVLGDQIIQQVCYMMHFMPTVMLISRLCPRGSESMVYAVLAGCAHFGRSVSNTLGWLLMEYVWNVQSDITVGPCDFSNVKWLLLLGHFGTPLISIPLVFLLIPAARICDVLDENGKAITKKAEDVHAPSNDSPRRREPTAN