wanglab/gogpt-training-data huggingface dataset:
Protein: Agamous-like MADS-box protein AGL104 (Q9LM46)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
Interaction partners:
- Agamous-like MADS-box protein AGL65
- CAP superfamily protein
- At5g26880
- Probable WRKY transcription factor 34
- At1g01310 superfamily protein)
- Basic leucine zipper 61
- AGAMOUS-like 94
- Agamous-like MADS-box protein AGL82
Sequence:
MGRVKLEIKRIENTTNRQVTFSKRRNGLIKKAYELSILCDIDIALIMFSPSDRLSLFSGKTRIEDVFSRFINLPKQERESALYFPDQNRRPDIQNKECLLRILQQLKTENDIALQVTNPAAINSDVEELEHEVCRLQQQLQMAEEELRRYEPDPIRFTTMEEYEVSEKQLLDTLTHVVQRRDHLMSNHLSSYEASTMQPNIGGPFVNDVVEGWLPENGTNQTHLFDASAHSNQLRELSSAMYEPLLQGSSSSSNQNNMSECHVTNHNGEMFPEWAQAYSSSALFASMQQQHEGVGPSIEEMMPAQQSDIPGVTAETQVDHEVSDYETKVPQLSSQ
Protein: TEF transcription factor, PAR bZIP family member a (Thyrotroph embryonic factor alpha isoform) (Q9W722)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Cryptochrome circadian regulator 5
- Sulfotransferase
- Cryptochrome-1
- Nr1d2b protein
- Bromodomain-containing protein 4
- Period circadian protein homolog 2
Sequence:
MKPISITMDAGAETSAAFPVVLKKIMETPPPNLLEGDDENDKEKLFESVESGGVSEMGPSAALTPAIWEKTIPYDGDTFHLEYMDLEEFLMENGIAAAENEQKSSEKENIQLTAEEPSTASAVKTAPAVTLLPVMALDPCEEEVVTITTSSSSSADNKSEENRMTPDPINPDEIEVDVNFEPDPTDLVLSSIPGGELFDPRKHRFSEEELKPQPMIKKAKKVFVPEDQKDDKYWQRRKKNNVAAKRSRDARRLKENQITVRAAFLERENSALRQEVAELRKDFGRCKNTVARYEAKYGAL
Protein: Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3) (M-Delta-3) (O88516)
Organism: Mus musculus (Mouse)
Function: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Neurogenic locus notch homolog protein 2
- Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 4
- Neurogenic locus notch homolog protein 3
- Delta-like protein 1
- Delta-like protein 4
- Recombining binding protein suppressor of hairless
- Transcription factor HES-5
- Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
- Achaete-scute homolog 1
Sequence:
MVSLQVSPLSQTLILAFLLPQALPAGVFELQIHSFGPGPGLGTPRSPCNARGPCRLFFRVCLKPGVSQEATESLCALGAALSTSVPVYTEHPGESAAALPLPDGLVRVPFRDAWPGTFSLVIETWREQLGEHAGGPAWNLLARVVGRRRLAAGGPWARDVQRTGTWELHFSYRARCEPPAVGAACARLCRSRSAPSRCGPGLRPCTPFPDECEAPSVCRPGCSPEHGYCEEPDECRCLEGWTGPLCTVPVSTSSCLNSRVPGPASTGCLLPGPGPCDGNPCANGGSCSETSGSFECACPRGFYGLRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPGFQGSNCEKRVDRCSLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGSRRCSCALGFGGRDCRERADPCASRPCAHGGRCYAHFSGLVCACAPGYMGVRCEFAVRPDGADAVPAAPRGLRQADPQRFLLPPALGLLVAAGLAGAALLVIHVRRRGPGQDTGTRLLSGTREPSVHTLPDALNNLRLQDGAGDGPSSSADWNHPEDGDSRSIYVIPAPSIYAREDWLIQVLF
Protein: Achbp (I6L8L2)
Organism: Capitella teleta (Polychaete worm)
Interaction partners:
Sequence:
SNGLMAKRLRRELLNTYEQLGKSGLPFLDDIGKVDVKFGLSLQLLKSIEQRGMGFNSIGTFKAIVKLSWVDTILRWDPEPPFDFQKIEISPDEIWTPDIKLFNSVDLDMTLDRTTQAIVFSNGTVLWIPPAVLKVLCVSQDDVDSCHFQFGSWVYSVDEVDIHFMDDKAEVLLDFYQDSLEILENSAQRQEVVYPCCESAYVEMKYLLALRSENGNSTYSRDLAHHHHHH
Protein: Colony stimulating factor 2 receptor subunit beta (A0A8I5Y685)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MDQHMAFIWGLCYMALVALCWRHGVTKAEETVPLKTLQCYNDYIERIICSWADTEDAQGLVNLTLYHWLDKKQPMSCELSEDLMWSECPSSHRCVPRRCVLPYTQFSVSKEDYYSLQPDRDLSIHLVVPLAQHVQPPPPKDISISPSGDHFLLKWSVPHGDAQVSLLSQKDIQFEVAYKRLQDSWEDASSLHTSNLWVTLEPKLFLPNSIYVARVRTQLAPGSSLSGRPSRWSPEVHWDSPTGDKARPQNLQCFFDGIQSLNCSWEVWTKVTDSVSFGLFYSSSPKAGEKKCSPVVKELQASRYTRYHCSLNVSDPAAHSQYTVSVKRLEQGKFIESFNHIQMNPPTLNLTKNRDSYSLHWETQKMSYPFIQHAFQVQYKKKLDSWEDSKTENLNHAHSMDLPQLEPGTSYCARVRVKTIPEYKGLWSEWSNECTWTTDWVMPTLWIVLILVFLILTFLLALRFGCIYGCKLYRKWKEKIPNPSKSLLFQDGGKGLWPPGSTVTFSSKNPTPQGPQSNLFSELQGTKRKRSWTVVLESLP
Protein: beta-N-acetylhexosaminidase (EC 3.2.1.52) (Q95S03)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MALVKLNTFHWHITDSHSFPLEVKKRPELHKLGAYSQRQVYTRRDVAEVVEYGRVRGIRVMPEFDAPAHVGEGWQHKNMTACFNAQPWKSFCVEPPCGQLDPTVNEMYDVLEDIYGTMFDQFNPDIFHMGGDEVSTSCWNSSQPIQQWMKKQGWGLETADFMRLWGHFQTEALGRVDKVANGTHTPIILWTSGLTEEPFIDEYLNPERYIIQIWTTGVDPKVKKILERGYKIIVSNYDALYLDCGGAGWVTDGNNWCSPYIGWQKVYDNSLKSIAGDYEHHVLGAEGAIWSEQIDEHTLDNRFWPRASALAERLWSNPAEGWRQAESRLLLHRQRLVDNGLGAEAMQPQWCLQNEHECPIDACSRGSGRLGLIVLLLLTTLSA
Protein: Golgi pH regulator (Protein GPR89) (B2ZXD5)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:P0CG08}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSFLIDSSIMVTSQILFFGFGWLFFMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIQLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAVARRTMFQRGEVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVSSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITQVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP
Protein: RING-H2 finger protein ATL14 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ATL14) (Q9M0C3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- E3 ubiquitin protein ligase RIN3
- E3 ubiquitin protein ligase RIN2
- E3 ubiquitin-protein ligase CIP8
- Protein SPEAR3
- E3 ubiquitin-protein ligase AIRP2
- Brassinosteroid-responsive RING protein 1
- Probable pterin-4-alpha-carbinolamine dehydratase, chloroplastic
- E3 ubiquitin-protein ligase SINAT5
- E3 ubiquitin-protein ligase XBAT32
Sequence:
MSITIPYDGSISREPSPSPPPPKANTKNLPTKILSNFLIGLIMIPVAITAFIFILTSLGFTFFFAFYWFLQRNYRHRLRRHRRHEYSDGLSPRCVKRLPQFKYCEPSSEYGGDDCVVCIDGFRQGQWCRKLPRCGHVFHRKCVDLWLIKVSTCPICRDRVYRFEEGRRWRPQGEIF
Protein: Transcription elongation factor SPT4 (hSPT4) (DRB sensitivity-inducing factor 14 kDa subunit) (DSIF p14) (DRB sensitivity-inducing factor small subunit) (DSIF small subunit) (P63272)
Organism: Homo sapiens (Human)
Function: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.
Subcellular location: Nucleus {ECO:0000269|PubMed:8649394}.
Interaction partners:
- Transcription elongation factor SPT6
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB4
- Transcription elongation factor SPT5
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB3
- RNA polymerase-associated protein RTF1 homolog
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
Sequence:
MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGIIAMMSPEDSWVSKWQRVSNFKPGVYAVSVTGRLPQGIVRELKSRGVAYKSRDTAIKT
Protein: RNA polymerase II-associated factor 1 homolog (Q9VN55)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Hyrax
- FACT complex subunit Ssrp1
- Ctr9, isoform A
- Another transcription unit protein
- FACT complex subunit spt16
- Transcription elongation factor SPT5
- Uncharacterized protein
- Transcription elongation factor SPT4
- Uncharacterized protein
- FI06213p
Sequence:
MPPTINNSAVNSAAEKRPQRQTERKSEIICRVKYGNNLPDIPFDLKFLQYPFDSHRFVQYNPTSLERNFKYDVLTEHDLGVTVDLINRELYQADSMTLLDPADEKLLEEETLTPTDSVRSRQHSRTVSWLRKSEYISTEQTRFQPQNLENIEAKVGYNVKKSLREETLYLDREAQIKAIEKTFSDTKSEITKHYSKPNVVPVEVLPIFPDFTNWKFPCAQVIFDSDPAPAGKNVPAQLEEMSQAMIRGVMDESGEQFVAYFLPTEQTLEKRRTDFINGELYKEEEEYEYKIAREYNWNVKTKASKGYEENYFFVMRQDGIYYNELETRVRLNKRRVKVGQQPNNTKLVVKHRPLDSMEHRMQRYRERQLEVPGEEEEIVEEVREEEQMQIIGETEKTSEDAAVGAQAASGADSPAQVARDRQSRSRSRTRSGSSSGSGSGSGSRASSRSKSGSRSGSGSRSRTNSPAGSQKSGSRSRSVSRSRSRSKSGSRSRSRSRSKSGSRSRSGSRSGSGSRSPSRSRSGSPSGSGSSSGSASDE
Protein: ABC50 protein (ATP-binding cassette, sub-family F (GCN20), member 1) (Q2L6I2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMVSRPRE
Protein: Activity-dependent neuroprotector homeobox protein 2 (ADNP homeobox protein 2) (Zinc finger protein 508) (Q8CHC8)
Organism: Mus musculus (Mouse)
Function: May be involved in transcriptional regulation. May play a role in neuronal function; perhaps involved in protection of brain tissues from oxidative stress. May be involved in erythroid differentiation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MFQIPVQNLDNIRKVRKRVKGILVDIGLDSCKELMKDLKSFDPGEKYFYNTSWGDVSPWEPSGKKARYRTKPYCCSLCRYSTKVLTSLKNHLHRYHEDEADQELMIPCPNCPFSSQPRVVGKHFRMFHAPARKVQSYTVNILGETKTSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFNYLINSYFGLRTEETGEQPKASDPVSVDKILPFDKYYCKKCSAIASSQDALMYHILTSDAHRDLENKLRSVISEHIKRTGFLKQMHIAPKPVTHLALPPNSSAPSIAAPPPCFQLALPQNSQSSGTVQSVTVTPGTSGSLTHSPPTTAQSHVALVSSSLPVCQSSLSLQQSAPPPVFLSHSVALNQPVNTAVLPLTQPVGPVNKSVGTSILPVNQAMCSVNQAVRPGLLPLTKPMGPMNRPVGPAVLPMGPSVNSGVLQATSPGVISVGRAVPSGVLPAGQVTPAGVIPGQTATSGVLPTGQVVQSSTLPVGQTAPSRGLPPGQTVPLRVLPAGQVVPSGLLSSNQTVPSGVVPVNQGVNSGVLQLGQPVTPGVLPVGPPVRPGVLQLSPSVSTSILPMSQPVRAGTSQNTTFFTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPSGGGLAAVGPPPQVPVQFLPSGSGTQMGSSLPSLPSPQVLVSPAPSVFVQATPPLADANQALKQAKQWKTCPVCNELFPSNVYQVHMEVAHKQSEAQLCQVCNELFPANVYQVHMEVAHKQSESKSSEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSQEELMHHLLMHGLGCLFCPCTFHDVRGLVEHSRTKHLGKKRLSMDYSNRGFQLDLDANGNLLFPHLDFITILPREKLGEREVYLAILAGIHSKSLVPVYVKVRPQPEVAPKIPNKQKLTCPFCLSTFMTADAYELHLKERHHVMPTVHTMLRSPAFKCIHCCGVYTGNMTLGAIAVHLLRCRSAPKDSSSDLQVQPGFIESSELLMVNGDVIPESTFPVKRKLPEGHLGPEDQRDGEEPQLTLDADASSGSEKGLGAVPLKRQKSEIRTEGSGPSEDSLQALALDPSKYEGRSYEEKKQFLRDYFHRRPYPSRKEVELLSSLLWVWKIDVASFFGKRRYICMKAIKTHKPSVLLGFDMSELKNVKHRLNFGECESQKL
Protein: Glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) (Peptide N-myristoyltransferase) (Q8TFN1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
Subcellular location: Cytoplasm.
Interaction partners:
Sequence:
MSDSKDSKGKAPQKPNDAEQTPGGKLTPQAAEALLENNPSLKNELGGLDKDKALEALRKMDISELLTGLSLTGKNKKDMAAFKFWQTQPVPRFDEAASNAAGGPIKMIDPEKVSKEPDALIEGFEWTTLDLTNEEELRELWDLLTYHYVEDDNAMFRFRYSKSFLHWALMSPGWRKEWHVGVRATKSRKLVASISGVPTQIRVRGQKIKVTEINFLCIHKKLRSKRLAPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPRGSTKARQITKNHLPSHTSTPNLRPMEAKDVDAVHDLLERYLNQFDIHQAFTREEIDHWLVYKESPQKEQVIWSYVVEDPETHKITDFFSFYNLESTVIQHPKHDCVRAAYLYYYATETAFLDDQKALKNRLQMLMNDALILAKKAQFDVFNALTSHHNPLFLEQLKFGAGDGQLHFYLYNYRTAPIAGGVNEKNLPDENRMGGVGVVML
Protein: Sex-determining region Y protein (Testis-determining factor) (Q05066)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:11818535}. Cytoplasm {ECO:0000269|PubMed:15297880, ECO:0000269|PubMed:19349578}. Nucleus {ECO:0000269|PubMed:15297880, ECO:0000269|PubMed:15746192, ECO:0000269|PubMed:16762365, ECO:0000269|PubMed:19349578, ECO:0000269|PubMed:28030592}. Note=Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (PubMed:15297880). Colocalizes with SOX6 in speckles (PubMed:11818535). Colocalizes with CAML in the nucleus (PubMed:15746192). Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity). Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (PubMed:19349578). {ECO:0000250|UniProtKB:Q05738, ECO:0000269|PubMed:11818535, ECO:0000269|PubMed:15297880, ECO:0000269|PubMed:15746192, ECO:0000269|PubMed:19349578}.
Interaction partners:
- Zinc finger Y-chromosomal protein
- Steroidogenic factor 1
- Doublesex- and mab-3-related transcription factor 1
- Histone demethylase UTY demethylase UTY)
- Wilms tumor protein
- Ubiquitin carboxyl-terminal hydrolase 9Y
- Nuclear receptor subfamily 0 group B member 1
- Zinc finger X-chromosomal protein
- Testis-specific Y-encoded protein 1
- Muellerian-inhibiting factor
Sequence:
MQSYASAMLSVFNSDDYSPAVQENIPALRRSSSFLCTESCNSKYQCETGENSKGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKAKMLPKNCSLLPADPASVLCSEVQLDNRLYRDDCTKATHSRMEHQLGHLPPINAASSPQQRDRYSHWTKL
Protein: Small ribosomal subunit protein eS21 (40S ribosomal protein S21) (Q9CQR2)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P63220}. Cytoplasm {ECO:0000269|PubMed:36517592}. Rough endoplasmic reticulum {ECO:0000250|UniProtKB:P63221}. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity). {ECO:0000250|UniProtKB:P63220, ECO:0000250|UniProtKB:P63221}.
Interaction partners:
- Small ribosomal subunit protein eS10
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS15
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein uL14
Sequence:
MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRTTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF
Protein: DnaJ homolog subfamily C member 15 (Q6DDA1)
Organism: Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Function: Negative regulator of the mitochondrial respiratory chain (By similarity). Plays a role in the translocation of proteins across the mitochondrial inner membrane (By similarity). Involved in pronephric kidney development at the early tadpole stage.
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit Tim23
- Hypothetical LOC496605
- Transmembrane and coiled-coil domain family 1
- Stress-70 protein, mitochondrial
- Golgi to ER traffic protein 4 homolog
- Ubiquitin-like protein 4A
- Large proline-rich protein bag6
- Reactive oxygen species modulator 1
Sequence:
MATSSTGMGTSEALRYSEYMPGPNAGSSTDIDRRLGGTLIAVGLGVAAAAFAGRFAFQLWKPLGQVIAESAKKIPTPSLSYYYKGGFEQKMNRREASLILGVSPSASKSKIRAAHRKIMILNHPDKGGSPYMAMKINEAKDLLESTTKP
Protein: Probable medium chain fatty-acid-CoA ligase FadD14 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) (O53406)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- NADPH oxidoreductase
- Conserved protein
- SRPBCC family protein
- Seven-bladed beta-propeller protein Rv1057
- PNPLA domain-containing protein
- Conserved protein
- Phthioceranic/hydroxyphthioceranic acid synthase
- Mycocerosic acid synthase-like polyketide synthase
- Mycoketide-CoA synthase
- Phenolphthiocerol/phthiocerol polyketide synthase subunit C
Sequence:
MYGTMQDFPLTITAIMRHGCGVHGRRTVTTATGEGYRHSSYRDVGQRAGQLANALRRLGVTGDQRVATFMWNNTEHLVTYFAVPSMGAVLHTLNIRLFPEQIAYVTNEAEDRVILVDLSLARLLAPVLPKLDTVHTVIAVGEGDTTPLREAGKTVLRFAELIDAESPDFGWPQIDENSAAAMCYTSGTTGNPKGVVYSHRSSFLHTMAACTTNGIGVGSSDKVLPIVPMFHANGWGLPYAALMAGADLVLPDRHLDARSLIHMVETLKPTLAGAVPTIWNDVMHYLEKDPDHDMSSLRLVACGGSAVPESLMRTFEDKHDVQIRQLWGMTETSPLATMAWPPPGTPDDQHWAFRITQGQPVCGVETRIVDDDGQVLPNDGNAVGEVEVRGPWIAGSYYGGRDESKFDSGWLRTGDVGRIDEQGFITLTDRAKDVIKSGGEWISSVELENCLIAHPDVLEAAVVGVPDERWQERPLAVVVVREGATVSAGDLRAFLADKVVRWWLPERWAFVDEIPRTSVGKYDKKAIRSRYAEGAYQITEVHT
Protein: SKP1-like protein 5 (AtSK5) (Q9M1X4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Cullin-1
- Cullin-like protein 3
- Cullin-2
- Putative cullin-like protein 2
- Putative cullin-like protein 1
- RING-box protein 1a
- RING-box protein 1b
- F-box protein 7
- Elongin-C
- Cullin-3A
Sequence:
MSTKIMLKSSDGKSFEIDEDVARKSIAINHMVEDGCATDVIPLRNVTSKILKIVIDYCEKHVKSKEEEDLKEWDADFMKTIETTILFDVMMAANYLNIQSLLDLTCKTVSDLLQADLLSGKTPDEIRAHFNIENDLTAEEVAKIREENQWAFQ
Protein: Pantothenate kinase CAB1 (EC 2.7.1.33) (Coenzyme A biosynthesis protein 1) (Pantothenic acid kinase CAB1) (Q04430)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Plays a role in the physiological regulation of the intracellular CoA concentration.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pantoate--beta-alanine ligase
- Phosphopantothenate--cysteine ligase CAB2
- Coenzyme A biosynthesis protein 3
- Phosphopantetheine adenylyltransferase
- Dephospho-CoA kinase CAB5
- 2-dehydropantoate 2-reductase
- Coatomer subunit gamma
- Phosphopantothenoylcysteine decarboxylase subunit SIS2
- Phosphopantothenoylcysteine decarboxylase subunit VHS3
- Pantothenate transporter FEN2
Sequence:
MPRITQEISYNCDYGDNTFNLAIDIGGTLAKVVFSPIHSNRLMFYTIETEKIDKFMELLHSIIKEHNNGCYRMTHIIATGGGAFKFYDLLYENFPQIKGISRFEEMEGLIHGLDFFIHEIPDEVFTYNDQDGERIIPTSSGTMDSKAIYPYLLVNIGSGVSILKVTEPNNFSRVGGSSLGGGTLWGLLSLITGAQTYDQMLDWAQEGDNSSVDMLVGDIYGTDYNKIGLKSSAIASSFGKVFQNRMTSNKSLENNENKLYSSHESIEKNNGQMFKNPDICKSLLFAISNNIGQIAYLQAKINNIQNIYFGGSYTRGHLTTMNTLSYAINFWSQGSKQAFFLKHEGYLGAMGAFLSASRHSSTKKTST
Protein: Zinc finger and SCAN domain-containing protein 1 (Q8NBB4)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
Interaction partners:
- Zinc finger protein 174
- Zinc finger protein 24
- Zinc finger and SCAN domain-containing protein 18
- PiggyBac transposable element-derived protein 1
- Zinc finger protein 213
- Myeloid zinc finger 1
- Plasmalemma vesicle-associated protein
Sequence:
MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHVASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCREAASLVEDLTQMCQQEVLVSLDSVEPQDWSFGEEEDGKSPRSQKEPSQASELILDAVAAAPALPEESEWLETTQLQQSLHTRAEAEAPRAPGLLGSRARLPLKPSIWDEPEDLLAGPSSDLRAEGTVISSPKGPSAQRISPRRRNRNTDQSGRHQPSLKHTKGGTQEAVAGISVVPRGPRGGRPFQCADCGMVFTWVTHFIEHQKTHREEGPFPCPECGKVFLHNSVLTEHGKIHLLEPPRKKAPRSKGPRESVPPRDGAQGPVAPRSPKRPFQCSVCGKAFPWMVHLIDHQKLHTAHGHM
Protein: ODAD1 central coiled coil region domain-containing protein (Q57ZQ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- BTB domain-containing protein
- BRCT domain-containing protein
- IF rod domain-containing protein
- Uncharacterized protein
- Flagellar attachment zone protein 1 conserved domain-containing protein
- Tubulin alpha chain
- ODAD1 central coiled coil region domain-containing protein
Sequence:
MHEEDPEVAKYKQSVIDVGQRTQLELLQAEVRHNKECLTALRLENKRLNVILQQAQRGQRRGVEIDPLRREEEQLHNKLCLLKRSLNSVHGKKEELTKEIARTVEETGYILQEGKFTTDNSAMGQKIRGLENRLDKCLIKHNEVNAIRRTYEALLERLQQEQAGFDTQLAAMEKTLQNKEKDLCDLNTVAAEASNGRDAAKAEVLRLKAQLTRERRAQNKDLEERRAFVMTKQKQLDRKAQRLKDKIERDEERRAGQHMAGGNQQKKVSRVTTQKPERREDVEQQQQLREAYNKLKEVTMSNTVDEVISKLQERQDANAQLMQTAEEAEEADAMLKEERSQLMEEWEKLQQQNVVHRSVLKGENQKPPATEERTTGGANSVANVAEQRALVRRRVLEEFESYLNDRKNELNVAQRVQEGLGQLLMDLGAGVQRLADTVACATINVMSASTHVSMFDEVCEDELAFCNARGDSIVSVLNSTAAKLENMLELVDVEDVASVATSIYNWRYSLPPTNVCIRLETSATPADGGSGELGSDHSDSGGVSGKGRRTSADEMPVGCRRWFGPAPTDDFPENEIHDRHELKQMSIATVERERKKARKLQQQRVKDETI