wanglab/gogpt-training-data huggingface dataset:
Protein: Valosin-containing protein homolog (Q38B27)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- MPN domain-containing protein
- SEP domain-containing protein
- Ubiquitin fusion degradation protein, putative
- Ubiquitin thioesterase OTU
- UBX domain-containing protein
- UBX domain-containing protein
- Ubiquitin fusion degradation protein 2, putative
- Guanine nucleotide-binding protein subunit beta-like protein
- Polyubiquitin, putative
Sequence:
MSAKAQQVKQQKLNRLIADDLAEDDNSVVVLNAKRMDELSIFRGDTVKLKGKKNRSTICIAMSDENCPEGSIMVNKVTRRNIRILLGDLITVSSHSNVPYGNHVHVLPIDDTVKNLTGDLFETFLKPYFLEAYRPVKTGDLFICRGAMRSVEFKVVEVDPGDCCIVAPETVVHCEGDPIRREDEERLDDVGYDDIGGCRRQLVQIREMVELPIRHPELFKSIGIKPPRGILMYGPPGSGKTLIARAVANETGAFFFLINGPEIMSKMAGESEGNLRNAFVESEKNAPAIIFIDEIDSIAPKREKAQGEVEKRIVSQLLTLMDGLKGRSQVIVMAATNRPNAIDPALRRFGRFDREIDIGVPDEIGRLEILRIHTKNMKLHPNVDVEKIAKDSHGYVGADLAQLCTEAAMQCVREKMAVVDWDDETIDAEVLDSMSVTNNHFLDALSKMNPSALRETQVETPNVTWSDVGGLLDVKRELQELVQYPVEFPWKFEKYGISAPKGVLFYGPPGCGKTLLAKAIATECQANFISIKGPELLTMWFGESEANVRDVFDKARAAAPCVLFFDELDSVARSRGHSGDGGASDRVINQILTEMDGMNSKKNVFIIGATNRPDVLDPAVMRPGRLDQLIYIPLPDKASRVAILKASFRKSPLAPDVDLDQLAAATHGFSGADLAGICQRACKLAIRESIAKEIQLEEARANGVLNEDQDIDPVPQITRLHVEEAMRGARRSVSDADIRKYELFATSLQQSRAFGNVSLDPGNQGGAGGDAGAGDDDLYS
Protein: GPN-loop GTPase 1 (EC 3.6.5.-) (Gro-1 operon protein 2) (XPA-binding protein 1 homolog) (P46577)
Organism: Caenorhabditis elegans
Function: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9HCN4}. Nucleus {ECO:0000250|UniProtKB:Q9HCN4}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250|UniProtKB:Q9HCN4}.
Interaction partners:
- GPN-loop GTPase 2
- GPN-loop GTPase 3
- Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
- Protein CLEC16A homolog
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- 1,4-alpha-glucan branching enzyme
Sequence:
MAEKAENLPSSSAEASEEPSPQTGPNVNQKPSILVLGMAGSGKTTFVQRLTAFLHARKTPPYVINLDPAVSKVPYPVNVDIRDTVKYKEVMKEFGMGPNGAIMTCLNLMCTRFDKVIELINKRSSDFSVCLLDTPGQIEAFTWSASGSIITDSLASSHPTVVMYIVDSARATNPTTFMSNMLYACSILYRTKLPFIVVFNKADIVKPTFALKWMQDFERFDEALEDARSSYMNDLSRSLSLVLDEFYCGLKTVCVSSATGEGFEDVMTAIDESVEAYKKEYVPMYEKVLAEKKLLDEEERKKRDEETLKGKAVHDLNKVANPDEFLESELNSKIDRIHLGGVDEENEEDAELERS
Protein: Germ cell-less homolog 1 (Drosophila) (Q53SE7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGSLSSRVLRQPRPALAQQAQGARAGGSARRPDTGDDAAGHGFCYCAGSHKRKRSSGSFCYCHPDSETDEDEEEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWSLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVEALQVAFGSLYRDDVLIKPSRVVAILAAACLLQLDGLIQQCGETMKETVNVKTVCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQNVELFKELSINVMKQLIGSSNLFVMQVEMDIYTALKKWMFLQLVPSWNGSLKQLLTETDVWFSKQRKDFEGMAFLETEQGKPFVSVFRHLRLQYIISDLASARIIEQDAVVPSEWLSSVYKQQWFAMLRAEQDSEVGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDLLVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRTTGYQILTLEKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKKN
Protein: Phototropin (EC 2.7.11.1) (Blue light receptor PHOT) (Q8LPD9)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Protein kinase that acts as a blue light photoreceptor. Required for non-photochemical quenching (NPQ), a mechanism that converts and dissipates the harmful excess absorbed light energy into heat and protect the photosynthetic apparatus from photo-oxidative damage. Controls the energy-dependent chlorophyll fluorescence quenching (qE) activity of chlorophyll excited states by inducing the expression of the qE effector protein LHCSR3 in high light intensities.
Subcellular location: Membrane {ECO:0000269|PubMed:12121468}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- UV-B photoreceptor
- Photosystem II protein PSBS1
- COP1
- COP9 signalosome complex subunit 2
- Light-harvesting complex stress-related protein 3.1, chloroplastic
- Light-harvesting complex stress-related protein 3.2, chloroplastic
- Channelopsin 1
- 14-3-3-like protein
Sequence:
MAGVPAPASQLTKVLAGLRHTFVVADATLPDCPLVYASEGFYAMTGYGPDEVLGHNCRFLQGEGTDPKEVQKIRDAIKKGEACSVRLLNYRKDGTPFWNLLTVTPIKTPDGRVSKFVGVQVDVTSKTEGKALADNSGVPLLVKYDHRLRDNVARTIVDDVTIAVEKAEGVEPGQASAVAAAAPLGAKGPRGTAPKSFPRVALDLATTVERIQQNFCISDPTLPDCPIVFASDAFLELTGYSREEVLGRNCRFLQGAGTDRGTVDQIRAAIKEGSELTVRILNYTKAGKAFWNMFTLAPMRDQDGHARFFVGVQVDVTAQSTSPDKAPVWNKTPEEEVAKAKMGAEAASLISSALQGMAAPTTANPWAAISGVIMRRKPHKADDKAYQALLQLQERDGKMKLMHFRRVKQLGAGDVGLVDLVQLQGSELKFAMKTLDKFEMQERNKVARVLTESAILAAVDHPFLATLYCTIQTDTHLHFVMEYCDGGELYGLLNSQPKKRLKEEHVRFYASEVLTALQYLHLLGYVYRDLKPENILLHHTGHVLLTDFDLSYSKGSTTPRIEKIGGAGAAGGSAPKSPKKSSSKSGGSSSGSALQLENYLLLAEPSARANSFVGTEEYLAPEVINAAGHGPAVDWWSLGILIFELLYGTTPFRGARRDETFENIIKSPLKFPSKPAVSEECRDLIEKLLVKDVGARLGSRTGANEIKSHPWFKGINWALLRHQQPPYVPRRASKAAGGSSTGGAAFDNY
Protein: Ferric uptake regulation protein (Ferric uptake regulator) (P74739)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Ferric uptake regulation protein
Sequence:
MSYTADSLKAELNARGWRLTPQREKILTIFQNLPEGEHLSAEELHHRLEEEREKISLSTVYRSVKLMSRMGILRELELAEGHKHYELQQASPHHHHHVVCVQCNRTIEFKNDSILKQSLKQCEKEGFQLIDCQLTVTTICPEAIRMGWPSTLPSNWACTRSISLA
Protein: Lectin (P86922)
Organism: Ganoderma lucidum (Ling zhi medicinal fungus) (Bracket fungus)
Function: Has metal-independent hemagglutinating activity against erythrocytes from human, sheep, goat, rat, rabbit and chicken. Hemagglutinating activity is inhibited by glycoproteins fetuin, asialo-fetuin, fibrinogen, asialo-fibrinogen, thyroglobulin, bovine (BSM) as well as porcine submaxillary mucin and asialo-BSM but not by sugars alpha-L-fucose, D-glucose, D-galactose, D-glucosamine, D-galactosamine, lactose, D-melibiose, D/L-mannose, D-mannosamine, D-raffinose, L-rhamnose, xylose, glacaturonic acid or N-acetylglucosamine. Has antifungal activity against F.oxysporum (MIC=20 ug/ml), P.chrysogenum (MIC=35 ug/ml), A.niger (MIC=50 ug/ml), C.musae (MIC=60 ug/ml), B.cinerea (MIC=65 ug/ml), T.rubrum (MIC=65 ug/ml), T.tonsurans (MIC=20 ug/ml), T.interdigitale (MIC=20 ug/ml), E.floccosum (MIC=15 ug/ml) and M.canis (MIC=70 ug/ml).
Interaction partners:
Sequence:
TGVAWRIT
Protein: Supercoiling factor (O96051)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQTVYGFMDDLSPDEKEQEENGVSYKSLLKRDRYRWSVADQDLDDNLTKDEFTAFLHPEDHPSMKGVVLRETITDLDKDHDGKISVDEYIGDMYRSTGAAEDEEPEWVANEREAFSTHRDLDKDGYLNEEEVKQWIAPHDFDHSEAEAKHLLFEADADHDDKLTKEEILDKYDVFVGSQTTDFGEALARHDEF
Protein: Prorelaxin 1 [Cleaved into: Relaxin B chain; Relaxin A chain] (P47932)
Organism: Mus musculus (Mouse)
Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.
Subcellular location: Secreted.
Interaction partners:
- Relaxin receptor 1
- Relaxin-3 receptor 2
- Relaxin-3 receptor 1
- Insulin-like 3
- Relaxin receptor 2
- Relaxin-3
- Insulin-like peptide INSL5
- Insulin-like peptide INSL6
Sequence:
MSSRFLLQLLGFWLLLSQPCRTRVSEEWMDGFIRMCGREYARELIKICGASVGRLALSQEEPALLARQATEVVPSFINKDAEPFDTTLKCLPNLSEELKAVLSEAQASLPELQHAPVLSDSVVSLEGFKKTLHDRLGEAEDGSPPGLKYLQSDTHSRKKRESGGLMSQQCCHVGCSRRSIAKLYC
Protein: Defensin-like protein 14 (Cysteine-rich antifungal protein At2g26010) (Plant defensin 1.3) (O80995)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Confers broad-spectrum resistance to pathogens. Has antifungal activity in vitro.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- AT5g15220/F8M21_110
- Defensin-like protein 6
- F-box associated ubiquitination effector family protein
- RNA-binding
- Protein kinase family protein
- Defensin-like protein 4
- Defensin-like protein 1
- Defensin-like protein 2
- Defensin-like protein 10
- Defensin-like protein 197
Sequence:
MAKSAAIITFLFAALVLFAAFEAPIMVEAQKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYFPC
Protein: Condensin-2 complex subunit (Q9VMQ4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR036508}.
Interaction partners:
- Chromosome associated protein H2, isoform E
- Structural maintenance of chromosomes protein
- Condensin complex subunit 2
- Structural maintenance of chromosomes protein
- Chromosome associated protein G, isoform F
- Condensin complex subunit 1
- Structural maintenance of chromosomes protein
- Structural maintenance of chromosomes protein 5
- Retinoblastoma family protein
Sequence:
MSDFHRIFGDLRVYYEPNVQWVDVEEWLYGEEAEGSVLQQRAEKFWTMAMCLQDGGHQETQLQLLRDLSAIIRAMRDENQASYSNTHDNWSNLIGFSPALGYLTYIYSLVSLVVLPEHVQQAAPQQLNENINMQLALNAATTYLLTLTIPGAKIFGVFDEDVIEQVLKVFRLLEMNNNKSLRASMIWMFFLTICDDLKIVFRYVHFKEHLKTRDRIIRCLLEVLYMNFKMGYQNTCAPGLHGKCFELFSEIANEHNGDVYETLHLIMRQTFPMHVYTDSPQMIAYGRRGAMQSGEHISDWFIQLIDKYPDIVNRILHFYIECVVSNPIKAWKSNDEKVAIGYAAKYDRVLFTKCNKSCADYVLEAVKADDAVGIQIRALDLIEKILLQESEVEWSIFRHEVSDVPREVPLLREVLRCLNDRTLTVRRKACQVLILALRQGSPMTKKILQESIRFVQFDDTDVEALAEPSAQQNELRFEKPGIVQYAFSFQGHEQLETEVKNLPQTVYQRFLAADNGLARSAGIALLERLVLVNPLIIYNTNFVKETSLLAVDRLSSVRKSALETIETLLEAYSNCFALICVYCRIWACLMSDEDVALQKLAISSFDRMVLKNIQPLEYSNEAKHFMPWRIISTLLMTQPRAYLQERFAVLLERETIVTPRLVNVIISHLSTSMATDAWGLLLFLSSRITNNMDALIGIFNGLSSYNMKSNQFLALQLITGCLRNFSKPALNQLFQKLLNALRTGSIWLGIISSAVNLLNQIHHLSTSQSPTIASEMPYWQLSLLEDLVEGILSSAQNFQEEYARLQCLLGAYTELIVMVPQDVDNRIVSIVFKYLQECTKLCESEFDSDNERMTNWMIVIAGRLSLRDNHLANSASKLYITILTKNDRPQIINTTLIALNDLGKKHPSILESNFQAILSKLQSKFAMTRVRTFRCVKDVILSGNIKLKGPILISMLAALVDESAEVAREADAFFTRYKKLYNKMLFDHCLKECPFDLNDQAILRGVRTNGNYKSPLKGSQMAKKRRLLYNHIMSSMDENVLLLYFGQLKLLAEKTRDQAFINNPDALIVVQDMLFIMRRICYCTKGMGKEKNSRGEGDNIDEGEDASSEPATPPTRPEAGEATSRGRGRKADMSEEPLKQLERCLRFVEETHRNIVPVMSPELSHNFESFCRAMAMRFPNYIEFAQPAQFWRQFRSSAKAPRASRSKRRRMEEGEVESHEEHESESDSDSELPLDRHKTTPTASRLSQRKTSCDMLVTELIFQPPDW
Protein: Caldesmon 1 (C9J813)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKS
Protein: Glucosidase 2 subunit alpha (EC 3.2.1.207) (Alpha-glucosidase II subunit alpha) (Glucosidase II subunit alpha) (Reversal of TOR2 lethality protein 2) (P38138)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalytic subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16373354}.
Interaction partners:
- Mannosyl-oligosaccharide glucosidase
- Glucosidase 2 subunit beta
- Calnexin homolog
- Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
- Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Killer toxin-resistance protein 5
- Protein KRE1
- Protein BIG1
- Protein ROT1
Sequence:
MVLLKWLVCQLVFFTAFSHAFTDYLLKKCAQSGFCHRNRVYAENIAKSHHCYYKVDAESIAHDPLENVLHATIIKTIPRLEGDDIAVQFPFSLSFLQDHSVRFTINEKERMPTNSSGLLISSQRFNETWKYAFDKKFQEEANRTSIPQFHFLKQKQTVNSFWSKISSFLSLSNSTADTFHLRNGDVSVEIFAEPFQLKVYWQNALKLIVNEQNFLNIEHHRTKQENFAHVLPEETTFNMFKDNFLYSKHDSMPLGPESVALDFSFMGSTNVYGIPEHATSLRLMDTSGGKEPYRLFNVDVFEYNIGTSQPMYGSIPFMFSSSSTSIFWVNAADTWVDIKYDTSKNKTMTHWISENGVIDVVMSLGPDIPTIIDKFTDLTGRPFLPPISSIGYHQCRWNYNDEMDVLTVDSQMDAHMIPYDFIWLDLEYTNDKKYFTWKQHSFPNPKRLLSKLKKLGRNLVVLIDPHLKKDYEISDRVINENVAVKDHNGNDYVGHCWPGNSIWIDTISKYGQKIWKSFFERFMDLPADLTNLFIWNDMNEPSIFDGPETTAPKDLIHDNYIEERSVHNIYGLSVHEATYDAIKSIYSPSDKRPFLLTRAFFAGSQRTAATWTGDNVANWDYLKISIPMVLSNNIAGMPFIGADIAGFAEDPTPELIARWYQAGLWYPFFRAHAHIDTKRREPYLFNEPLKSIVRDIIQLRYFLLPTLYTMFHKSSVTGFPIMNPMFIEHPEFAELYHIDNQFYWSNSGLLVKPVTEPGQSETEMVFPPGIFYEFASLHSFINNGTDLIEKNISAPLDKIPLFIEGGHIITMKDKYRRSSMLMKNDPYVIVIAPDTEGRAVGDLYVDDGETFGYQRGEYVETQFIFENNTLKNVRSHIPENLTGIHHNTLRNTNIEKIIIAKNNLQHNITLKDSIKVKKNGEESSLPTRSSYENDNKITILNLSLDITEDWEVIF
Protein: alpha-1,2-Mannosidase (EC 3.2.1.-) (Q57W81)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
Sequence:
MKGAQFLKMPCVRVLLVLVRVFFVHLPSFAFGDAFPVNGARGGNSQGYNTDGMHPIQAEMLPYVRDMIDHAFGSYIKYAFPKDELCPVSGTGKNTMGGYGWTLIDSLDTLAIAGFHKEFRRHAKWVEEHLTFDIDESVSVFETTIRALGGLLAAHFMYEEGIVPIIPSEHDYNGGFLRLAVDLADRLMPCFDTPTGIPYGKVNLRRGVSGGESQLANTAGSGTLLVEMTVLSRITGDGKYERAARRASEALFAARDSQTELMGTYVSVSSGGFSSSESSVGSGLDSAIEYFIKSHSMSGDIGDWERFERTARAVNRYVRKGGMLLAASMYSGRRLQTSQESLSSFFPGNLVLGGHLHEAVESSWPIHTFFKHFGVLPEIFSLESGEPSWRSHDYIGRPEHIESLYMLYRATRDPTYLLMGKELALAINLRMRTPYGFSSVSDVRYPHHDGVHRDSMESFMIAETLKYLYLLFDECNAVHVQGRMGGRASPHCVMDSGSGSSVSHVGWVFNTEAHLFPNSAEWWAPTSLETLDKEAEDPAAALRRQRLEVIDGLLASFEEVDGEVVGANDKGGAALYQFHCANHALSDVGRLSKSVFR
Protein: Ankyrin repeat and SOCS box protein 2 (ASB-2) (Q96Q27)
Organism: Homo sapiens (Human)
Function: Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Mediates Notch-induced ubiquitination and degradation of substrates including TCF3/E2A and JAK2. Required during embryonic heart development for complete heart looping (By similarity). Required for cardiomyocyte differentiation.
Subcellular location: Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:24044920}.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:Q8K0L0}. Note=Localizes to the Z line in cardiomyocytes. {ECO:0000250|UniProtKB:Q8K0L0}.
Interaction partners:
- Cullin-5
- RING-box protein 2
- Elongin-C
- Ankyrin repeat and SOCS box protein 17
- Filamin-A
- Elongin-B
- Cytokine-inducible SH2-containing protein
Sequence:
MATQISTRGSQCTIGQEEYSLYSSLSEDELVQMAIEQSLADKTRGPTTAEATASACTNRQPAHFYPWTRSTAPPESSPARAPMGLFQGVMQKYSSSLFKTSQLAPADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPAPQPSSRFNDAPAADKEPSVVQFCEFVSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ
Protein: acid phosphatase (EC 3.1.3.2) (F4J355)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable protein phosphatase 2C 10
- Phosphatidylglycerophosphate phosphatase PTPMT2
- Inositol diphosphatase DSP4
- Inositol diphosphatase DSP2
- Inositol diphosphatase DSP5
- Inositol diphosphatase DSP3
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN2B
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
- Dual specificity protein phosphatase PHS1
- Mitochondrial carrier protein MTM1
Sequence:
MMMYCPNLTASLTIPSYLPFCHYTRQFRPSHFRSSDKNPNLVSIIRAKPRISHSLRCFVSSSMATPPPTQSSETKPYSVLFVCLGNICRSPAAEGVFRDIVKKRGLDSKFNIDSAGTIDYHEGNMADPRMRSAAKRRGIEITSLSRPIKASDFREFDLILAMDDQNKEDILKAYNVWKARGNFPPDADKKVPLVCVCWTLELYLVDRFSLNFQVKLMCSYCKKHNDKFVPDPYYGGAQGFEKVLDLLEDACESLLDSITAQS
Protein: Germ cell-specific gene 1 protein (Germ cell-associated protein 1) (Q8R1W2)
Organism: Mus musculus (Mouse)
Function: May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18325338}; Multi-pass membrane protein {ECO:0000269|PubMed:18325338}. Note=Colocalizes with PAPOLB in the endoplasmic reticulum.
Interaction partners:
Sequence:
MAKMEFQKGSSDQRTFISAILNMLSLGLSTASLLSSEWFVGTQKVPKPLCGQSLAAKCFDMPMSLDGGIANTSAQEVVQYTWETGDDRFSFLAFRSGMWLSCEETMEEPGEKCRRFIELTPPAQRWLSLGAQTAYIGLQLISFLLLLTDLLLTTNPGCGLKLSAFAAVSLVLSGLLGMVAHMLYSQVFQATANLGPEDWRPHSWNYGWAFYTAWVSFTCCMASAVTTFNMYTRMVLEFKCRHSKSFNTNPSCLAQHHRCFLPPPLTCTTHAGEPLSSCHQYPSHPIRSVSEAIDLYSALQDKEFQQGISQELKEVVEPSVEEQR
Protein: V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Q9CR51)
Organism: Mus musculus (Mouse)
Function: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:29993276}.
Interaction partners:
- V-type proton ATPase subunit F
- V-type proton ATPase subunit D
- V-type proton ATPase subunit B, brain isoform
- V-type proton ATPase subunit E 1
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase subunit C 1
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase subunit H
- V-type proton ATPase 16 kDa proteolipid subunit c
- V-type proton ATPase 116 kDa subunit a 1
Sequence:
MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSHGSCSSEVEKETREKMTVLQNYFEQNRDEVLDNLLAFVCDIRPEIHENYRING
Protein: MHC class I molecule (A0ZXM3)
Organism: Gallus gallus (Chicken)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MGPCGALGLGLGLLLAAVCGAAAELHTLRYIQTAMTDPGPGQPWFVTVGYVDGELFVHYNSTARRVVPRTEWMAANTDQQYWNGQTQIVQGNEQIDRDDLGTLQRRYNQTGGSHTVQLMYGCDILEDGTIRGYSQDAYDGRDFIAFDKGTMTFTAAVPEAVPTKRKWEEGDYAEGLKQYLEETCVEWLRRYVEYGKAELGRRERPEVRVWGKEADGILTLSCRAHGFYPRPIVVSWLKDGAVRGQDAQSGGIVPNGDGTYHTWVTIDAQPGDGDKYQCRVEHASLPQPGLYSWEPPQPNLVPIVAGVAVAIVAIAIVVGVGFTIYRRHAGKKGKGYNIAPDREGGSSSSSTGSNPAI
Protein: Down syndrome cell adhesion molecule 1, isoform E (A1Z6X2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVAQYYDTDVNKAYVIRGNAAVLKCEIPSFVADFVSVVSWHTDQNEDFLPGSEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGFKAPSFPSVASTFTIQSPKKSELALTCEAQSYPVPIFKWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWTTAPDPTTGVGRLMSNDGILITKTTQRISMLSIESVHARHRANYTCVARNAAGVIYHTAELRVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Protein transport protein SEC23 G (AtSEC23G) (Protein transport protein SEC23 C) (Protein transport protein SEC23 E) (AtSEC23E) (Q84WI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:P15303}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P15303}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}. Membrane {ECO:0000250|UniProtKB:P15303}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}.
Interaction partners:
- Protein transport protein SEC13 homolog B
- Protein transport protein SEC24 C
- Protein transport protein SEC13 homolog A
- Protein transport protein SEC31 homolog B
- Protein transport protein SEC31 homolog A
- Protein transport protein SEC24 A
- Protein transport protein SEC24 B
- Protein transport protein SEC23 D
- small monomeric GTPase
- small monomeric GTPase
Sequence:
MDFLELEAIEGLRWSWNSWPTTKSDCESLVVPLSIMYTPLMHFSELPTIPYDPLICSRCGAVLNPYARVDYQSRIWSCPFCFHKNLFPRSYSGITETNLPAELFPTYSAVEYSPLPSRQSGSNTTTPTAAASWSNGFNQGVRSMPSNSSFSSLASSTVGGGGGVISELGPAFVFVVDASMVEDELRAVRSDVLFVIEQLPENCLVALITFDSMVRVYDLGFSECSKVVVFHGERDLSPDQIQQFLGLGYSKQFHHGKMSAIRKQSFLLPLVECEFNLTSAFEEIIPLVDVKPGHRPHRSTGAAISTALGLLEGCSVTTGSRIMVFTSGPATRGPGIIVDSDLSNSIRTHRDIITGHVSYYDKSCGFYKKLAKRLCDSSVVLDVFACSLDQVGAAELRYAVEMSGGFLLLGETFESEQFKKCLRHIFIRDADGNLSMYFDVSLEVVTTKDMRICGALGPVVSLRQKNDIVSETEIGEGGTYMWKTSTVTNKTCVSFFFHVSNEQNRKPQPGSAFFIQFITRYRYGNGAMRKRVTTVARRWVAGKSPEISSSFDQETAASVMARLAINRAEECHARDVITWLDNGLIRFASRFGDYIQEDPSSFRLTPNFSLYPQFMFYLRRSQFLDVFNNSPDETGFFRLMLNREGVVNSIIMIQPTLLRYSFDGPPVPVLLDIRSVTPDVILLFDSYFYVVIHHGSKIAQWRKLEYHKDPSHETFRNLLEAPEIDAAQLVTDRIPMPRIVRCDQHGSQARFLLAKLNPSVTQKTDHTGGSDIVLTDDMSLQDFLEDLQSLAVKG
Protein: Protocadherin 18 (Protocadherin-18b precursor) (A9CPE6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MGTTKHSSDWNVLFCKTLLKLMLLAAVAHNVSGKTLKYKVLEEQRVGTVIARLKEDVAGLLAKLPSSVSPRFRAMQRGSTPLLSVREEDGEISIATKIDREKLCEKNLNCTIEFDVITIPTEYLQLFHIQVEVLDINDNAPQFSRAIIPIEISESASVGTRFPLDSAVDPDVGENALHTYSLTRNNFFKIDIRTRTDGAKYADLVVMRELDRETQSSYQLQLTASDSGVPPKSGSTLLKISISDSNDNSPAFDEQAYVVNLLENSSLETLLVDLNATDPDEGNNGKIVYSFSSHVPPKILETFKINPDNGHITLIKKVDYETTSSYEIDVQAQDMGPNSIPGHCKIIIKVVDVNDNKPKININLMTQGKEEVAYISEASPVDTFIALVRVDDSDSGINGEVVCRLHGHGHFRLQKTYENNYMILTNVSLDREKRSEYSLTVIAEDRGTPSLSTIKHFTVQVQDENDNPPRFEKSRYEIFKSENNSPGAYLTSVVATDPDLGPNGQVTYSIVESQVQGSSISTYVTIDPSNGAVYALRSFDREEVGRLSFTVQARDGGSPAFLSSNTTVLLTILDENDNPPIIVAPLLSNHTAEVPLWRHAESGHLVTIIKATDRDAGANSELTCSIVGGNDEGLFVIDPRRCELRTNGSVEASGREGFDLAILVQDRGASIRLSARAVLHISLRDYPESYSLNPSDINNQSPLDVSMIIIISLGAICGVLLIVMVMFATRCSREQKDPRHSYNCRVAESTYQNHPKKPARQIHKGDITLVPTINGTLPVRAHPRSPSASPAPESRQSHHSRQSLNSLVTISSNHVPENFALELAHATPPVEGQYQPRPSFRGNKYTRSYRYALNEMDKFSLKDSGRGDSEAGDSDCEMGRESPLLGEGFSELFTPDGHHRLHPTMKLCTEECRVLGHSDQCWMPPLPSPASSDYRSNLYIPGEDPQQKATPEVPQSGESTLRKKSFSTFGKESEEGEGEADDGEDLCGTTSLLSEMNSVFQRLLPSSLDNYSETNETEKATACAAGVGSLERRKGHLPGKPSPATYQQNVAVWAANTHFQNPGHGHAPASHMTALVAPLPAPLPAPMPASASCSKWLPAMEEIPENHEEDELESVLGHLHGKRCDSRSEIMDASELVAEINKLLQDVRQS