wanglab/gogpt-training-data huggingface dataset:
Protein: Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Q9CXU0)
Organism: Mus musculus (Mouse)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 28
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 30
- Mediator of RNA polymerase II transcription subunit 20
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 11
Sequence:
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLSQKLNFIVTGLQDIDKCRQQLHDITVPLEVFEYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS
Protein: Flotillin-2a (Reggie-1a) (REG-1) (Q98TZ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May play a role in axon growth and regeneration. May be involved in epidermal cell adhesion and epidermal structure and function (By similarity).
Subcellular location: Membrane {ECO:0000250}. Endosome {ECO:0000250}. Note=In neuronal cells, associated with GPI-anchored cell-adhesion molecules. {ECO:0000250}.
Interaction partners:
- AP-2 complex subunit mu
- Low density lipoprotein receptor-related protein 1Aa.
Sequence:
MGNCYTVGPNEALVVSGGCCGSDGKTYTVGGWAWAWWLITDIQKITLEIMTLQPKCEDVETAEGVAITVTGVAQVKVMTDNELLGYACEQFLGKTVTEIKSVILQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKSQTAAVQRDADIGVAEAERDAGIREAECKKEMMDIKFQADTKMADSKRELEMQKAAFNQEVNTKKAEAQLAYELQAAKEQQKIRLEEIEIEVVQRKKQISIEEKEILRTDKELIATVRRPAEAEAFKMEQLAEAKKIKKVLTAQAEAEKIKRIGEAEAGSIEAVGKAEAEKMRLKAEAYQQYGEAAKTALVLEALPKIAGKVAAPLGRTNEIVILSGDGGRVTGEVNRLLAELPVSVNALTGVDLSKIPLLQKMTNPQA
Protein: Unconventional myosin-VI (Unconventional myosin-6) (A0A8I6AEW8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection, microvillus {ECO:0000256|ARBA:ARBA00004105}. Cell projection, ruffle membrane {ECO:0000256|ARBA:ARBA00004632}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane, clathrin-coated pit {ECO:0000256|ARBA:ARBA00004600}.
Interaction partners:
Sequence:
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNVKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSDTIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYVKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAPSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANSARDALAKTVYSHLFDHVVDRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEVKLVGILDILDEENRLPQPSDQHFTSVVHQKHKDHFRLTIPRKSKLAVHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRALFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPEKLARLDPRLFCKALFKALGLNEVDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNLWLVCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSALKDGKPEVNRQIKDLEISIDALMAKIKSTMMTREQIQKEYDALVKSSEDLLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEQRRRKEEEERRMKLEMEVKRKQEEEERKKREDDEKRIQAEVEAQLARQREEESQQQAVLAQECRDRELALRIAQNESELISDEAQGDTALRSSSSCPASSKEQMAKEMSDILSRGPAVQATKAAAGTKKHDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFAPFLNNSPQQNPAAQLPARQQEIEMNRQQRFFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQSAIESRQARPTYATAMLQNLLK
Protein: Neuronal acetylcholine receptor subunit alpha-4 (P09482)
Organism: Gallus gallus (Chicken)
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: Synaptic cell membrane {ECO:0000250|UniProtKB:O70174}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O70174}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Neuronal acetylcholine receptor subunit beta-2
- Neuronal acetylcholine receptor subunit beta-3
- Neuronal acetylcholine receptor subunit alpha-6
- Acetylcholine receptor subunit alpha
- Neuronal acetylcholine receptor subunit alpha-2
Sequence:
MGFLVSKGNLLLLLCASIFPAFGHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPQEYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRIKWMPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLVSMHSHVDQLDYWESGEWVIINAVGNYNSKKYECCTEIYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSPRTHTMPDWVRRVFLDIVPRLLFMKRPSTVKDNCKKLIESMHKLTNSPRLWSETDMEPNFTTSSSPSPQSNEPSPTSSFCAHLEEPAKPMCKSPSGQYSMLHPEPPQVTCSSPKPSCHPLSDTQTTSISKGRSLSVQQMYSPNKTEEGSIRCRSRSIQYCYLQEDSSQTNGHSSASPASQRCHLNEEQPQHKPHQCKCKCRKGEAAGTPTQGSKSHSNKGEHLVLMSPALKLAVEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI
Protein: A kinase (PRKA) anchor protein 12b (A-kinase anchor protein 12b isoform 2) (F2Z4T4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}.
Interaction partners:
- Rho guanine nucleotide exchange factor
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase
Sequence:
MLGTITLTVGQTDTISPKEDSPETIEVHQEEVAPQMNGEKGDDSANADEITTAEEKVVEEKQEEANEVGFKKIFRFVGFKFTLKKDKNEKTEPVQLLTVKEAESGADAATEEKKEEPAAEEDRSVEEKSPETTENEAKAEEVTEKAEEPAEQTVVDAPSETEKVSDIETEKPAEETGTISEKEPEPEVPAESPTSPPSQETQSPFKRFFTQGIFSNLRKKASFKKPKDEEHVKEKPVEEDIKETEETAEGVPEATEEAKVDAENEPAEGEQIEKPSETVETKAETTTETTAETTNEVTPTEKEEQQDLKVEAEATSEVETVTHTEPAQAPAVETTQPTDDAKTSDKPDISEEAPTEPEILSSQEKSKAHGSPLKKLFTGAGLKKLSSKKHKNKKDAESKQTESSEQTAETVQSTESTEPQKPDSGASSPEESGEHVVGEVAQAEVAQAVEPDGDAVTSDGEKKKEGILPWSSFKKLVTPKKRVKRPSESEDEAPGDKPKSSTLSSTESAISDEKADEPKPSEEVPSKEELKEEAKEESQAESKTEPKAEKSESVAEEPKRKMDTSVSWEALICVGSSKKRARKTSDSDDEEAKIEEEVQPSEEEPIKTAESPLVSSGEADHENLASSPEPEGELVSTWESFKRLVTHRKKAKAEDKSDEASGPEQTTSDSETPKEESSFSLRKLIPRRKKKSDGKQEQVSSDVGSAEDDSDTPAVVPLSEYDSEPSAEAAVKAEEVKQESATVTQAKASAEDRSPSWISTTVENVEDETEGNQLSDIPEEGDTAATPKSTDNTIAEDIVELTSEAVTALEQVEETEMVSAVSRVTASPDTSGETTPVPGDGVERKTDVVIQEAVETISVTTNAMAVTMTEEQETVVAITTDALLVESATKEQKTVLVAHEKNEAVAVCTGLDTSEIRAVEEESLNQKPSVESATVVSQPLVTEVAVEEKTQEPERVTVTEDEVHEAQTSGVQAELKDQPIENAIEEKAQFEEIKDTPIAETVADIHEVAAVKVAVISAVQQEPEILEEPVMAEKSPEIESAGPVEATVEEAICAQTAEVTEVAVAEGEKVQELDDVKETVATVEVASVENVSTAVTEEVMATLPEVPASQIAGSTEDPIPVVAATEEFAVIKETICVSSISETTESHSADIAKETLMENVPVVLSTGDHKMQVAVNEVEVVSAQGVVEGNIEAASTKLSVALEEVTENVKEETEIIQATQVTEAEIIEKQSSVIVQEIIQNVVENFAEAHGEQNVSEKTTEESCITSAEVKVNEISVETTEEGSSTDKLAASDNVCKDVEETRIVTEKPPKIVNEAIQIAETVPVSITDEIQAQNEEVASVSVADVHQETEVTKSEVELKQAEEKSQSTKNEEGISEVESDLKEVQAEIQQEIKAVPEEKTAETSVTVASQDQVVAEQCQVTLTAVQIETAQEFNVGVVNVINADDVPETNMKEDCSEGQESTEDRPQNDLEEPQTKVSTNQEESRGPDCQKTDAKNVPAKLEAASEMTSNATAAEEVGNEIEPVSTEVVTVS
Protein: CCN family member 4 (ELM-1) (WNT1-inducible-signaling pathway protein 1) (WISP-1) (Q99PP0)
Organism: Rattus norvegicus (Rat)
Function: Downstream regulator in the Wnt/Frizzled-signaling pathway (By similarity). Associated with cell survival. Adheres to skin and melanoma fibroblasts (By similarity). In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan (By similarity).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Biglycan
- Protein Wnt
- Decorin
Sequence:
MRWLLPWTLAAVAVLMVGNILATALSPTPTTMTFTPAPLEETITRPEFCKWPCECPQAPPRCPLGVSLITDGCECCKICAQQLGDNCTEAAVCDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYTNGESFQPNCRYNCTCIDGTVGCTPLCLSPRPPRLWCRQPRHVRVPGQCCEQWVCDDDARRPRQTALLDTRAFAASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPCDVDIRPHIKAGKKCLAVYQPEEATNFTLAGCVSTRTYRPKYCGVCTDNRCCIPYKSKTISVDFQCPEGPGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFAEIAN
Protein: Phospholipid-transporting ATPase VD (EC 7.6.2.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D) (Q8K2X1)
Organism: Mus musculus (Mouse)
Function: Catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of the plasma membrane.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9P241}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9P241}; Multi-pass membrane protein {ECO:0000255}. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B. {ECO:0000250|UniProtKB:Q9P241}.
Interaction partners:
Sequence:
MTELLQWARHHWRRLSHGRAQGEDERPYNYASLLACGGKSSRTPRPAGKHRVVIPHLQCFKDEYERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYTEQDSEVDPEKFSSRIECESPNNDLSRFRGFLEHANKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIWLSRYENMLFFNIPEPDGRVISPVLTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVSEEEECTDTLGGSLSNMARPRAQGCRTVPSGPLGKPSAQLSGSTSAVGNGEGSGEVPHSRQAAFSSPMETDVVPDTRLLDKFSQLTPQLLTGLDGTAQSSPLETLYIMDFFIALAICNTVVVSAPNQPRQKIGLSSLGGMPIKSLEEIKNIFQKLSVRRSSSPSLASGKDSSSGTPCAFVSRISFFSRPKLSPPMEDESSQMDEIPQASNSACCTETEAQNRAVGLSVSSAEALSGPPPSASNLCYEAESPDEAALVYAARAYRCTLQSRTPEQVMVDFAALGSLTFQLLHILPFDSVRKRMSVVVRHPLSKQVVVYTKGADSVIMELLSVAASDGTNPEQQMIIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDACGMLMSAILEELQKRAQVSPELASSRKNFPQPSDAQGQGRAGLVITGKTLEFALQESLQRQFLELTAWCQAVICCRATPLQKSEVVKLVRNHHHVLTLPIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYRSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDIDIFTFGNPLNTAALFIILLHLVIESKSLTWIHMLVTVGSILSYFFFALAFGALCVTCNPPSNPYGIMRKHMLDPVFYLVCVLTTFVALLPRFLYRVLQGSVFPSPVLRAKYFDRLPPEERAEALKRWRGTAKVNHVASKHASQSAAMSGRPTPGSSAVLAMKSATVSTVEQSTRETALDRGCSEPGASKMTGSSAS
Protein: Crossover junction endonuclease MUS81 (V6CJ54)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MARRREEKEKDKETRKIEREISAATNSKCELYTFCHVGKTVIDTWHGLEAELSVLYVERKIDNQLKIDTSLGTRIEWRRKCVELREDDSGRSERFEYSSTQNLFAVVVPAETLKDVISSNTLSDFIIEQKSGFQNGGRCTMLIVSFGRAEIAKKKKLHNLSLQIYEQHRAQIVQIETIAELALFTAQYLRSLARQEKKKLDAGSDGGGGGGAGGAGGHKLQYQGDKGIVIGSRSEIVTDWWSKMLTTIDRLSDAQRRAILELIPDPIAAIDKYSKMDYSLAIQEIGELVAENGRRVGPSMAHRILTMLTDETGNSVVE
Protein: Inner tegument protein (EC 3.5.1.-) (EC 3.5.1.44) (Viral deamidase UL37) (P10221)
Organism: Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Function: Plays an essential role in cytoplasmic secondary envelopment during viral egress. Interacts with the capsid via the large tegument protein/LTP and participates in its transport to the host trans-Golgi network (TGN) where secondary envelopment occurs. Modulates tegumentation and capsid accumulation at the viral assembly complex (By similarity). Plays a role in microtubule-based retrograde axonal transport to promote neuroinvasion. Also plays a role in the inhibition of host immune response by acting as a viral deamidase. Deamidates host RIGI on two asparagines which becomes unable to sense viral dsRNA. In turn, its ability to trigger antiviral immune response and restrict viral replication is inhibited. Deamidates also a critical asparagine on host CGAS which abolishes cGAMP synthesis and downstream innate immune activation.
Subcellular location: Virion tegument {ECO:0000255|HAMAP-Rule:MF_04043, ECO:0000269|PubMed:7856080}. Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04043, ECO:0000269|PubMed:20505007, ECO:0000269|PubMed:7856080}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04043, ECO:0000269|PubMed:17223150, ECO:0000269|PubMed:7856080}. Host Golgi apparatus, host trans-Golgi network {ECO:0000255|HAMAP-Rule:MF_04043, ECO:0000269|PubMed:20505007}.
Interaction partners:
Sequence:
MADRGLPSEAPVVTTSPAGPPSDGPMQRLLASLAGLRQPPTPTAETANGADDPAFLATAKLRAAMAAFLLSGTAIAPADARDCWRPLLEHLCALHRAHGLPETALLAENLPGLLVHRLVVALPEAPDQAFREMEVIKDTILAVTGSDTSHALDSAGLRTAAALGPVRVRQCAVEWIDRWQTVTKSCLAMSPRTSIEALGETSLKMAPVPLGQPSANLTTPAYSLLFPAPFVQEGLRFLALVSNRVTLFSAHLQRIDDATLTPLTRALFTLALVDEYLTTPERGAVVPPPLLAQFQHTVREIDPAIMIPPLEANKMVRSREEVRVSTALSRVSPRSACAPPGTLMARVRTDVAVFDPDVPFLSSSALAVFQPAVSSLLQLGEQPSAGAQQRLLALLQQTWTLIQNTNSPSVVINTLIDAGFTPSHCTHYLSALEGFLAAGVPARTPTGHGLGEVQQLFGCIALAGSNVFGLAREYGYYANYVKTFRRVQGASEHTHGRLCEAVGLSGGVLSQTLARIMGPAVPTEHLASLRRALVGEFETAERRFSSGQPSLLRETALIWIDVYGQTHWDITPTTPATPLSALLPVGQPSHAPSVHLAAATQIRFPALEGIHPNVLADPGFVPYVLALVVGDALRATCSAAYLPRPVEFALRVLAWARDFGLGYLPTVEGHRTKLGALITLLEPAARGGLGPTMQMADNIEQLLRELYVISRGAVEQLRPLVQLQPPPPPEVGTSLLLISMYALAARGVLQDLAERADPLIRQLEDAIVLLRLHMRTLSAFFECRFESDGRRLYAVVGDTPDRLGPWPPEAMGDAVSQYCSMYHDAKRALVASLASLRSVITETTAHLGVCDELAAQVSHEDNVLAVVRREIHGFLSVVSGIHARASKLLSGDQVPGFCFMGQFLARWRRLSACYQAARAAAGPEPVAEFVQELHDTWKGLQTERAVVVAPLVSSADQRAAAIREVMAHAPEDAPPQSPAADRVVLTSRRDLGAWGDYSLGPLGQTTAVPDSVDLSRQGLAVTLSMDWLLMNELLRVTDGVFRASAFRPLAGPESPRDLEVRDAGNSLPAPMPMDAQKPEAYGHGPRQADREGAPHSNTPVEDDEMIPEDTVAPPTDLPLTSYQ
Protein: Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1) (Q8TAD8)
Organism: Homo sapiens (Human)
Function: Required for pre-mRNA splicing as component of the spliceosome. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:10887155, ECO:0000269|PubMed:29360106}.
Interaction partners:
- Splicing factor 3B subunit 1
- RNA-binding motif protein, X-linked 2
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- BUD13 homolog
- Pre-mRNA-splicing factor CWC22 homolog
- SNW domain-containing protein 1
- Spliceosome-associated protein CWC27 homolog
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
- Splicing factor 3B subunit 3
- Serine/arginine repetitive matrix protein 2
Sequence:
MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS
Protein: Wasp kinin PMM1 (Bradykinin-related peptide) (P85873)
Organism: Polistes major (Neotropical social wasp)
Function: Induces relaxation of arterial smooth muscle, by targeting bradykinin receptors (BDKRB) (By similarity). May cause hypotension.
Subcellular location: Secreted {ECO:0000269|PubMed:17559065}.
Interaction partners:
Sequence:
KRRPPGFTPFR
Protein: Alstrom syndrome 1b, isoform B (M9PJ28)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
- FI01301p
- Salto, isoform A
Sequence:
MFKKFGSRDNRPAKLTRVHPPPGDYYISAMATDRELDRFMALSSTASSGASGSTQSCALGSVQPPGCASMEHEARPESGHRRRTKSSDHRSPDERGEAKEQLRELSVSPPPSKHNISQFTSPKSEVTQTKPNEYTIIPIVLASSPSFRSVAVTQTMSQSAGDIRRPIKSPQMQNKKTQTLESVHKSHKHTKKCQCKSRRQDSKVSSCQTDIHHPEREQQEIQPLMRDQRKAKQRHEKDHQLEREQQGIQQLTRDQRKATKREKVREQERQYTAAQFEKIRGNRRHVSKENQQPENPVVNPSTGVTASSSTTSLDVGSGSRPRGVLDIGIELVCSLVKSRSLSQGQKKKLVRDIARRISCLELTESSTSSRSLSSSSKEQLKVPTGSLQQVAATNTNQSNARSSSKAERIAPPVPAPRKRAAIGSSSPLPESVSYSGSTSGSGEVITQKTNIPNRNASTDADIEPLDLQDWLNPMTLSEIEFEERLKGGTDSERRRQLHWVKTEINRMQEFKNLLESISLPSKSQKKANTESATAAQIPSSMRCMGDQKERPDKEYLLRQEMSAEAESKEMENSETTTTPPPPVRIESVGVNVTNSDPSTLPAPPPTQPPPPPPHLNQRNLQNRKKMATPLLVSGSSTSGGGRSESVCSFVQQRQRQFCEHYENEQLEEFVLLQKQKLYQLRKQLNQQKDILIQRQQHCGQRTYVHQQHCPRRQQEAQDQHDEREQYMQMQYAQAAGAYASGAVGNEAIYHQVVNPQGVASYVQATMVSTETQNEATATGGAGGSSITRCETTTRQYDDVACQRVRRGHKETRMNAERMQRQVRPRAISYVIQFTPTGSSEVIEKPPSLQDQLQLARPEFCANAKQRKAILNEMQMIRNARRQELDNVLSQSTSMEALNRHLEQLPPAANTRVKLFTTREMKAITSKRCKNLPEVLAAQSRQEEEQRRRSNRLMRDAFNKSHLSKQRLKSRVASGNISQRGNHLEKIE
Protein: Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1) (Q03598)
Organism: Caenorhabditis elegans
Function: E2-like enzyme which forms an intermediate with ufm-1. The intermediate is formed via a thioester linkage (By similarity).
Interaction partners:
- Ubiquitin-like modifier-activating enzyme 5
- Ubiquitin-fold modifier 1
- E3 UFM1-protein ligase 1 homolog
- Ufm1-specific protease
- DDRGK domain-containing protein 1
- NEDD8-conjugating enzyme ubc-12
- Adenylyltransferase and sulfurtransferase MOCS3
- Ubiquitin-like protein
- ASC-1
Sequence:
MDDATKSSLKAIPLCKTKASPRDGDLWIERLKEEYEAIIAAVQNNKDCDRDWFQLESNERGTKWFGKCWYFHNMVKYEFDVEFDIPITYPVTAPEIALPELDGKTAKMYRGGKICLSEHFKPLWARNTPKFGIAHAFALGLGPWMAVEIPDLIEKGLIQPKA
Protein: Anthrax toxin receptor (A0A8I5ZVI5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MVAGRSRARSPGSWLFPGLWLLTVGGPGSLLQAQEQPSCKKAFDLYFVLDKSGSVANNWIEIYNFVHQLTERFVSPEMRLSFIVFSSQATIILPLTGDRYKISKGLEDLKAVQPVGETYIHEGLKLANEQIQNAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKKSRSLGASVYCVGVLDFEQAQLERIADSKDQVFPVKGGFQALKGIINSILAQSCTEILELSPSSVCVGETFQVVLSGRAVMSIRDDGSVLCTFTANSTYTKNEKPVSVQPGSILCPAPVLNKAGETLEVSIAFNDGKSAVSRSLTITATECSNGIAAIIAILVLLLLLGAALMWWFWPLCCKVVIKDPPPPPSPPKEEEEEEPLPNKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVMIPEEEIPVPSRPPRPKPTHQAPQTKWYTPIKGRLDALWALILKQYDRVSLMRPQEGDEARRNGKRDILCLLRKGSHAYQEKTLTIYYLWQRKHRSLPV
Protein: fructose-bisphosphatase (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase) (A0A1D8PKW2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Transketolase
- Transaldolase
- Glucose-6-phosphate isomerase
- Fructose-bisphosphate aldolase
- ATP-dependent 6-phosphofructokinase
- ATP-dependent 6-phosphofructokinase
- fructose-2,6-bisphosphate 2-phosphatase
- N-acetylglucosamine kinase 1
- Mannose-6-phosphate isomerase
- Phosphotransferase
Sequence:
MSGPVNSVSKQMNVDTDIITLTRFILQEQQTVAPTATGELSLLLNALQFAFKFIAHNIRRAELVNLIGVSGSANSTGDVQKKLDVIGDEIFINAMRSSNNVKVLVSEEQEDLIVFPGGGTYAVCTDPIDGSSNIDAGVSVGTIFGVYKLQEGSTGGISDVLRPGKEMVAAGYTMYGASAHLALTTGHGVNLFTLDTQLGEFILTHPNLKLPDTKNIYSLNEGYSNKFPEYVQDYLKDIKKEGYSLRYIGSMVADVHRTLLYGGIFAYPTLKLRVLYECFPMALLMEQAGGSAVTIKGERILDILPKGIHDKSSIVLGSKGEVEKYLKHVPK
Protein: Hexosyltransferase (EC 2.4.1.-) (Q7JZU2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}.
Interaction partners:
Sequence:
MDRRWNPEKIEEQSSLLAAEYSSSSGAAASGSEDETVTTSGALRSKAKLRKRQLRNRMPLPRMLRRLGCYTLSAFLICGLLLVYLPLVYLDVHKRSAGLPDWTSETSRSIADYLDIGLSSGVIVPKDFCRNKTFLVIAVCTGVDNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLTASVRIVFIVGRQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFNTAVYFLKCDDDTFITTTGPPI
Protein: Solute carrier family 25 member 3 (Phosphate carrier protein, mitochondrial) (Phosphate transport protein) (A0A024RBE8)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
Sequence:
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGSAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTQ
Protein: Leucine-rich repeat protein kinase family protein (Leucine-rich repeat receptor-like protein kinase) (Putative receptor like protein kinase) (Q8GX94)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- LRR receptor-like Serine/Threonine-kinase
Sequence:
MGISNWVFSVISVATLFVSCSFALTLDGFALLELKSGFNDTRNSLENWKDSDESPCSWTGVSCNPQDQRVVSINLPYMQLGGIISPSIGKLSRLQRLALHQNSLHGNIPNEITNCTELRAMYLRANFLQGGIPPDLGNLTFLTILDLSSNTLKGAIPSSISRLTRLRSLNLSTNFFSGEIPDIGVLSRFGVETFTGNLDLCGRQIRKPCRSSMGFPVVLPHAESADESDSPKRSSRLIKGILIGAMSTMALAFIVIFVFLWIWMLSKKERKVKKYTEVKKQKDPSETSKKLITFHGDLPYSSTELIEKLESLDEEDIVGSGGFGTVYRMVMNDLGTFAVKKIDRSRQGSDRVFEREVEILGSVKHINLVNLRGYCRLPSSRLLIYDYLTLGSLDDLLHERAQEDGLLNWNARLKIALGSARGLAYLHHDCSPKIVHRDIKSSNILLNDKLEPRVSDFGLAKLLVDEDAHVTTVVAGTFGYLAPEYLQNGRATEKSDVYSFGVLLLELVTGKRPTDPIFVKRGLNVVGWMNTVLKENRLEDVIDKRCTDVDEESVEALLEIAERCTDANPENRPAMNQVAQLLEQEVMSPSSGIDYYDDSHSDYC
Protein: SEC24 homolog C, COPII coat complex component (G3X972)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004397}.
Interaction partners:
- Protein SEC13 homolog
- Protein transport protein Sec16A
- Protein transport protein Sec23A
- Protein transport protein Sec31A
- Protein transport protein Sec24A
- Protein transport protein Sec23B
- SEC24 homolog B, COPII coat complex component)
- Protein transport protein Sec16B
- SEC24 homolog D, COPII coat complex component)
- Small COPII coat GTPase SAR1A
Sequence:
MNVNQSAPPVPPYGQNQPIYPGYHQSSYGGQPGPAAPATPYGAYNGPVPGYQQAPPQGVPRAPPSSGAPPASAAQVPCGQTTYGQFGQGDIQNGPSSTAQMQRVPGSQQFGPPLAPVVSQPAVLQPYGPPPTSTQVTAQLAGMQISGAVAQAPPPSGLGYGPPTSLASASGNFPNSGPYGSYPQSQAPPLSQAQGHPGVQPPLRSAPPLASSFTSPASGGPQMPSMTGLLPPGQGFGSLPVNQANHVSSPPAPALPPGTQMTGPPVPPPPPMHSPQQPGYQLQQNGSFGPARGPQPNYESPYPGAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGSEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESGPLRCNRCKAYMCPLMTFIEGGRRFQCSFCSCVNDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDYLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVSESRAVITSLLDQIPEMFADTRETETVFAPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGTYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYACFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEENGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRAVLNSPVKTVRDTLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVSSMDVAETNVFFYPRLLPLTKSPLDSTAEPPAVRASEERLSSGDIYLLENGLNLFVWVGASVQQGVVQSLFNVSSFSQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRMRYMKLIVVKQEDKLEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS