wanglab/gogpt-training-data huggingface dataset:
Protein: Integrin beta-5 (P18084)
Organism: Homo sapiens (Human)
Function: Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Integrin alpha-V
- Vitronectin
- Fibronectin
- Integrin alpha-5
- Integrin alpha-3
- Integrin alpha-2
- Integrin alpha-1
- Integrin alpha-11
- Focal adhesion kinase 1
- Integrin alpha-10
Sequence:
MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTVD
Protein: Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) (Q9EQV6)
Organism: Rattus norvegicus (Rat)
Function: Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus.
Subcellular location: Lysosome {ECO:0000250|UniProtKB:O14773}. Melanosome {ECO:0000250|UniProtKB:O14773}.
Interaction partners:
- Protection of telomeres protein 1
- Protection of telomeres protein 1
- Telomeric repeat-binding factor
- TERF1
- Palmitoyl-protein thioesterase 1
- Telomeric repeat-binding factor
- Telomeric repeat-binding factor 2-interacting protein 1
- Battenin
- CLN6, transmembrane ER protein
- CST complex subunit CTC1
Sequence:
MGLQARFLGLLALVIAGKCTHSPEPDQRWMLPPGWVSLGRVDPEEELSLTFALKQQNLDRLSELVQAVSDPSSPRYGKYLTLEDVAELVQPSPLTLRTVQKWLLAAGARDCHSVTTQDFLTCWLSVRQAELLLPGAEFHRYVGGPAKTHIIRSPHPYQLPQALAPHVDLVAGLHRFPPLSSPRQRPEPQGVGPVGLHLGVTPSVLRQRYNLTARDVGSGTTNNSQACAQFLEQYFHNSDLTEFMRLFGSSFAHQASVARVVGKQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHEAQEPFLQWLLLLSNESSLPHVHTVSYGDDEDSLSSVYIQRVNTEFMKAAARGLTLLFASGDTGAGCWSVSGRHKFRPSFPASSPYVTTVGGTSFKNPFLVTNEVVDYISGGGFSNVFPQPSYQEEAVAQFLKSSSHLPPSSYFNASGRAYPDVAALSDGYWVVSNMVPIPWVSGTSASTPVFGGILSLINEHRLLNGRPPLGFLNPRLYQQHGAGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP
Protein: Protein S100-A6 (5B10) (Calcyclin) (Prolactin receptor-associated protein) (S100 calcium-binding protein A6) (P14069)
Organism: Mus musculus (Mouse)
Function: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative (By similarity).
Subcellular location: Nucleus envelope {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- Calcyclin-binding protein
- Annexin A11
- Annexin A2
- Protein S100-A10
- Advanced glycosylation end product-specific receptor
- Annexin A1
- Protein S100-A13
- Protein S100-A4
- Protein S100-A11
- Protein S100-A16
Sequence:
MACPLDQAIGLLVAIFHKYSGKEGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMDDLDRNKDQEVNFQEYVAFLGALALIYNEALK
Protein: Transcription factor bHLH144 (Basic helix-loop-helix protein 144) (AtbHLH144) (bHLH 144) (Transcription factor EN 130) (bHLH transcription factor bHLH144) (Q9ASX9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Nuclear transcription factor Y subunit C-10
- Transcription factor bHLH143
- Nuclear transcription factor Y subunit B-4
- Putative transcription factor bHLH041
- Transcription factor bHLH123
Sequence:
MQNNQFPHFSDEVGDRNMHNPYASGSSYDALFPPCAKLPYHGVELQPSAVCPKNFVIFDQTYDRSQVMYHPELTHKLMNTPSLNNLASTFQNEYVGGSYGNYGNYEQEVSSSYQEDPNEIDALLSADEDYEENDDNEGEEDGGDSEEVSTARTSSRDYGNTTAESCCSSYGYNNNNNNNSRKQSLSGSASSSNNDGKGRKKMKKMMGVLRRIVPGGEQMNTACVLDEAVQYLKSLKIEAQKLGVGHFSNQS
Protein: Peroxisomal membrane protein PEX13 (Peroxin-13) (Q9D0K1)
Organism: Mus musculus (Mouse)
Function: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix. Involved in the import of PTS1- and PTS2-type containing proteins (By similarity).
Subcellular location: Peroxisome membrane {ECO:0000250|UniProtKB:Q92968}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Peroxisomal membrane protein PEX14
- Peroxisomal biogenesis factor 19
- Peroxisomal targeting signal 1 receptor
- Peroxisome assembly protein 12
- Peroxisome biogenesis factor 10
- Peroxisomal targeting signal 2 receptor
- Peroxisomal ATPase PEX6
- Peroxisomal membrane protein 11B
- Peroxisomal membrane protein PEX16
- Peroxisome biogenesis factor 2
Sequence:
MASQPPPPPKPWESRRIPGAGPGPGSGPGPTYQSADLGPTLLTRPGQPTLTRVPPPILPRPSQQTGSNNVNTFRPAYSSFSSGYGAYGNSFYGSYSPYSYGYNGLGFNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQWMMGLRRGSENEDLWAESEGTVACLSAEDQATNSAKSWPIFLFFAVILGGPYLIWKLLSTHNDEVTDNTNWASGEDDHVVARAEYDFVAVSDEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRRGRKTIESSTMLKQQQSFTNPTLIKGVTTTNPLDEQEAAFESVFVETNKVSSAPDSTGKNGDKQDL
Protein: Basic proline-rich protein-like (Q9VR13)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Serpin 28F
- Accessory gland-specific peptide 26Aa
- Serpin 38F, isoform A
- ACP53C14A
- Accessory gland-specific peptide 26Ab
- Accessory gland protein Acp76A
- glutaminyl-peptide cyclotransferase
- ACP53C14B
- AT20289p
- Aquarius
Sequence:
MSKWNYMVIVIFLFVPGNMEFSFDRIRSGESYTPFHFPYVPDNFPTPSAPAPPPKPRPPPPPPPPPTTTRPPTTTPTPTTTPTPITTPPPPPPSAPPPPDPATPGVWYPLPIYGNAPQFGDPPGSHLLSNSGKPHPPGSQMPPNSGFVLPPAICSPPYGPPNQDGNPPGSQTPPNSELVPPPAIWNPAYEPPNQIGHPPESQAPTNSGFVPPPAIWNPPYGPPNPDGNPPESQTPPNSGFVPPPAIWSPSVGPTSEDGHPPESQAPSNSGFVPPLAICYPPFGQQNQIGHQPGSHKPPNSGIYPPSTGWIPPSGSLSQGGHPPGSQLPPNSGLPPGSIPPLRPPNQIGDPPGSQMPSNLGIYPPSMGWIPPSGSLIQGGHPPGSLYPPNSVLAPGSIPPLRPSNQGGHPPGSLLPPNVGIYPPSTGWIPPSGPLTQGGHPPGSQVPPNFVLPAGSIPPLGSPNQIGQPPGSLLPPNVGIYPPSTGWIPPSGPLTQGGHPTGSLLPPNTGLPPGSIPPLRPPNQGGHPPGSQKPPNVGIYPPSTGWIPPFGPLTQGGHPPGSLLPPNTGLPPGSIPPLGSPNQIGHPPGSQKPPNVGIYPPSTGWTPPSGPLTQGGHPPGSLLPPNTGLPPGSIPPLGSPNQIGHPPGSQKPPNVGIYPPSTGWIPPSGPLTQSGHPPGSLLPPNTGLPPGSIPPLRPPNQGGHPPGSQKPPNVGIYPPSTGWIPPSGPLTQGGHPPGSLLPPNTGLPSGSIPPLGSPNQIGHPPGSQKPPNSGIYPPSTGSIPPSGPLTQGGHPPGSLLPPNTGLPSGSIPPLGSPNQIGHPPGSQKPPNSGIYPPSTGWIPPSGPLTQGGHPPGSLLPPNTGLPPGSISPLGSPNQIGHPPGSQKPPNVGIYPPSTGSIPPLRPPNQGGHPPGSQKPPNVGIYPPSTGWIPPSGPLTQGGHPPGSQVPSNSVLPPGSIPPLRPPNQGRHPPGSQVPPNTGLPPGSIPPLGSPNQIGHPPGSQKPPNSGIYPPSTGSIPPSGPLTQGGHPPGSLLPPNTGLPPGSIPPLRPPNQGRHPPGSQVPPNSVLPPGSIPPLGSPIQIGRPVGSQKPASSKIRPPPPSEPQNPDNVPKQPVKNPPAGGNLNVNDIRIDRPN
Protein: FI14922p (Mismatch depedent uracil/thymine DNA glycosylase) (Thymine DNA glycosylase, isoform A (EC 3.2.2.27, EC 3.2.2.28)) (Thymine DNA glycosylase, isoform B) (Thymine DNA glycosylase, isoform C) (Q9V4D8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small ubiquitin-related modifier
- N-glycosylase/DNA lyase
- Recombination repair protein 1 endonuclease)
- Endonuclease III homolog lyase)
- Dorsal interacting protein 4
- tRNA
Sequence:
MQEESGSTPLLSSSFSYTPTVAPLVLKIALIQAARSFAASKYTIKVLLSLNLALSEQAIVQKAVKPICTVMASEVDASSGPEDGTVPTLMSLTPYITNLEHGNNESGKYVSGLPNNRKRQKLSILEHNTIQNNDVDNTEVEPNMDPKSKMSDTKSNKYSEMEKHLNDNSKIVIEGTISIGNSKRKSPEKLVPYDNDCYMPPEQALVTSVELVVPAPQTHSSNTPGRQSEEPNLSTLGESSTTPSSTIDNKLQYSTAGLYNSTSSTSILANDKIVGCANDSSNLNLRIPTKLVVTTASGDILIDDRRASLWTPHHDESGQRQQRTGTASSDTKQEPMNVSSELSYHHQNRHSELLLQIEKESSGSFLQASPIPLQDNHNNAASGQFGQTEETSNIDSQSHNNFYAQMMQPQHLLHNQHQQSMHEHSPRHQQPASYSGYITHYQNPPMFGAHQSEHHQRLNQQQQPLQHLLDCHGHLEQSTPISQQNQHHLSQQIHQHQHQQTHQRLPLRENYHDIIMDDFHEEPSHAFKLTLSPSNTKPENQDDGYETSAGDVLTPNSHSSSTHSITPQHQMQHSNIVLMTQNQKKSDDLQLTKVTLSGEAHTDPNACSSNSSQGQVLASQSHLELSEGTRCSSHASVVDPYSFMGEELHMHSPSHRHLDAVTTGPGRYGILVSNDTPECLSREMYRHSQQSTTVLEQTDSSSCGINFKPMPKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGDQAAKPKERKKHDRFNGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLTQEQMSADEDHKLIKQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVFNGKLIFEVFSGKKEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAADKVPFYAALKKFRDFLNGQIPHIDESECVFTDQRIRLCSAQQQVDIVGKINKTHQPPLGDHPSSLTVVSNCSGPIAGDAECGIVAEESDQVQSEKMIPQMDPTVPSSSNATDGKSFSYTAENTPLLPVSNHNPSINENNYLSVMGSQQPLSQQPLEKKKRGRPKKIKGQDIIDHSVGGKASIAGQHIPSHDFNNILNLSVMSGGGTIETPKKKRGRPKKLKPAIDNIMTVKQLQHGNNNLNTTAGLSASSMHPISMEHIAASPQSSHQMPPSLYNTPPPSHLLYTASASPMASPALNCNYTQVHGHGTPPVGQVASVAQGSSPVIDTQNDHLAQQKQSHHGNLGAGLDMRDHPHLGETPPPSSPNMCSTVDFDPPDEHSGSQVGSRVQNKAVELDHQHPQIMEKVQYDSPVPNTEANPAHPHENYQQWLSPHPHQSNQPAQKLTHRQQHPPMHHFHQEQTENWQRYEEQNSNPYMVISAHHQHLSPRLGNQTHQNSSPSGHISSDVAHKSLCGLESLVDQIPAIREQDCSNIPLATVAAAAAAVESRILSLQHQHQHPLQPHQQNQQNQQQQLKQCKQENSAHRESCRPTSENSNVSNSNFSVSSLAASASSARTDNAIYGNGETKGNNESSHHNSCDTNIDYPIHNQSAYHHTPHLIGSALGTNVNNSEPNLHTISHPHPPHPHPHSMYVDQAHHMAHIPSVNVNSMYGPAYGSHPQHTTGEYPGTHGHYSLGGSVQTAVPTSSATLHVPSPNYPFGHHPYGHTPPQANYPSYTHPHTHHHHSHPSHHLTVFDHLKPSDISGYGGF
Protein: AP-1 complex subunit gamma (Adaptor protein complex AP-1 subunit gamma) (Adaptor-related protein complex 1 subunit gamma) (Clathrin assembly protein complex 1 gamma large chain) (Gamma1-adaptin) (Q8I8U2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.
Subcellular location: Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}.
Interaction partners:
- AP-1 complex subunit beta
- AP-1 complex subunit mu
- AP-3 complex subunit beta
- Clathrin heavy chain
- AP-2 complex subunit mu
- AP-2 complex subunit sigma
- AP-3 complex subunit mu
- AP-4 complex subunit beta
- Calmodulin
- MHD domain-containing protein
Sequence:
MSSKLRDLIKTVRSCKTAAEERSQIAKESALIRTAMKEEDLESRQRNVAKLLYIHMLGYPTQFGQMECLKLIVSPSYADKRIGYLGLMLLLDEKQEVLLLATNCIRGDIMNSNQFIVGVSLCAFGNICSTAMARDISPEIEKVISHSNPYIRKKAALCAIRVLRKVPDLTENYIPKIKALLSERNHAVILTALTLIIEICEMDSTQIIHFKKMVPQLVRILKSLTSSGYLPEHDIGGVTDPFLQVKILRLLRILGQNDPEASDAMNDILAQVSTNTDSTKNVGNAILYECVQTIMTIESENGLKVMAINILGRFLLNRDNNIRYVALNTLSRVVNTDIQAVQRHRNTIVECLKDPDVSIRCRALDLIYSLVTESNIRVLVRELLNFLLIADAQFKSELVAKLCIVTEKYAPNKRWQIDTILRVMSIAGNFIPDEVPSNLIQLISSTPELSSYAVQKLYLALKQDITQQPLTQVGLWCIGEYGDLLVADKSQLPKDEDGLSLNVSEQAVIDIIDLIFRHATTTQATRQYSLTSLAKLSSRFSQSSLQRIKTMIDNYKQNINLELQQRACEYSTLFDFDKKASILDRMPPIEKQEESPHIGNKNIPTQTPPQQHYQQQQQQPQQQSSQFGSILDGLDSPTQSSANSGNNNNNNNKQGGNAMSLLEDIFGSAPTPTSNGNMNNNNNMNNMNNNMNNNYAMGGMGMNNNNNNSMGGMMNNNNNNNNNNNNNNNNNKSQASALLDIMGDLQLTPTPQQPQSQSQQALSPTNQTSVLQPVPQPLTFLVYQKHGLNISYECSKPQPNNLSLTNINMVITNTGSSPITNFSLQAAVPKYLKIQLLAPSSTVIPPNNSGEVTQVSKVLNSQQGQKPILLRLKLDFQINGQPFSDVPDTPLPSLF
Protein: U-box domain-containing protein 28 (EC 2.3.2.27) (Plant U-box protein 28) (RING-type E3 ubiquitin transferase PUB28) (Q9LXE3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as an E3 ubiquitin ligase.
Interaction partners:
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- SCY1-like protein 2 A
- SCY1-like protein 2 B
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- ARM repeat superfamily protein
Sequence:
MRSDDLYITTVPCFFKCPISLDVMKSPVSLSTGVTYDRVSIQRWLDDGNNTCPATMQILQNKEFVPNLTLHRLIDHWSDSINRRADSESPESDTPTRDEINAAIERFRIENDARSKILRFARESDENREFLAGKDDFVAMLVDLISDSRNFSDSQLLLVGEAVKILSMIRRKIFDRRRLSNLILTNGGDCLTSFFLLIKRGNPKLKIDCSAVLEFIAVDAESKLIIAKGEGLVTEIIKLISSDSDSSLIEANLSLLIAIASSKRVKLALIREKLVTKLTSLLTDPTTSVSVTEKCLKLLEAISSCKEGRSEICDGVCVETVVNKLMKVSTAATEHAVTVLWSVCYLFKEKKAQDAVIRINGVTKILLLLQSNCSLTVRHMLTDLLKVFKVNSRSCLSVYETKTTHIMPF
Protein: Cadherin 96Cb, isoform C (IP03306p) (C6SUV2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MRINHQWIYYAILSLCWFNKATLGAILDSRCYLEGGGSAESFLATEDLAVGSIIGKLRINGDANAETGDINLSLREKNAPVEIHPGTKELALSVELDKEGVRGPSSIYVNVICIRRHSTDPSFVIPVNVRVTDVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQFLNPLEGTLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPKFQRESYSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTIVQSQDAKYFRIHPHNGAISLLTPIGYADVANGATLVVKATQIDNPDRYALTTVQLTRPGSHSDLSTLAFVQKRFVMRIREDTAVGNRILALPTNKPGKHLKYVIPDPVNSQFFSVGSLGELVLAKPLDYEKMTKHEFQVLATDGMTNSTAELTLEVIDVNDWEPRFRETHYEFMVPKSSLQSRADSFEGVLIGKVEAADGDRNDKLELSLRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVHLIAIATDTGVPPRSTSVPVSVTMEGLTLARSGWNSNMLGMFGMIMGLFLMIIVALSCYIVRSKKQGKSASSGLGLGRNRVHSQAHSSVSSANLVTHEKLAGNGNGNGASVTSGGVSVLHMKHGGNITMANPMNNGLHHVASGASSSMALGSSAALLERERERERDRERQRESYAATVRSIVSRASANGQLFEEDEIEHDSLQTENNNRKVAATGVASGGVTTISTTPANAGSNLLSATDAMGSSENNLTVYF
Protein: Pre-mRNA-processing protein 45 (P28004)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in pre-mRNA splicing. Associated with the spliceosome throughout the splicing reactions, until after the second catalytic step.
Subcellular location: Nucleus {ECO:0000269|PubMed:12359070, ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pre-mRNA-splicing factor CEF1
- U2 snRNP component HSH155
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing helicase BRR2
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
- Splicing factor YJU2
- Pre-mRNA-splicing factor BUD31
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22
- Pre-mRNA-splicing factor PRP46
- Pre-mRNA-processing factor 19
Sequence:
MFSNRLPPPKHSQGRVSTALSSDRVEPAILTDQIAKNVKLDDFIPKRQSNFELSVPLPTKAEIQECTARTKSYIQRLVNAKLANSNNRASSRYVTETHQAPANLLLNNSHHIEVVSKQMDPLLPRFVGKKARKVVAPTENDEVVPVLHMDGSNDRGEADPNEWKIPAAVSNWKNPNGYTVALERRVGKALDNENNTINDGFMKLSEALENADKKARQEIRSKMELKRLAMEQEMLAKESKLKELSQRARYHNGTPQTGAIVKPKKQTSTVARLKELAYSQGRDVSEKIILGAAKRSEQPDLQYDSRFFTRGANASAKRHEDQVYDNPLFVQQDIESIYKTNYEKLDEAVNVKSEGASGSHGPIQFTKAESDDKSDNYGA
Protein: Signal recognition particle 19 kDa protein (SRP19) (P09132)
Organism: Homo sapiens (Human)
Function: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). Binds directly to 7SL RNA (By similarity). Mediates binding of SRP54 to the SRP complex (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10618370, ECO:0000269|PubMed:11682607}. Nucleus, nucleolus {ECO:0000269|PubMed:10618370, ECO:0000269|PubMed:11682607}. Nucleus, nucleoplasm {ECO:0000269|PubMed:11682607}. Note=Although the signal recognition particle complex acts in the cytoplasm, it assembles at least in part in the nucleus and/or the nucleolus. SRP19 nuclear import may be mediated by IPO8/Imp8 and TPNO1/Trn. {ECO:0000269|PubMed:11682607}.
Interaction partners:
- Signal recognition particle subunit SRP68
- Signal recognition particle subunit SRP54
- Signal recognition particle subunit SRP72
- Signal recognition particle 9 kDa protein
- Signal recognition particle 14 kDa protein
- Signal recognition particle receptor subunit alpha
- Signal recognition particle receptor subunit beta
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein eL19
- Ribosomal protein uL24-like
Sequence:
MACAAARSPADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNVFLEKNKMYSREWNRDVQYRGRVRVQLKQEDGSLCLVQFPSRKSVMLYAAEMIPKLKTRTQKTGGADQSLQQGEGSKKGKGKKKK
Protein: Alpha-xylosidase (EC 3.2.1.177) (P31434)
Organism: Escherichia coli (strain K12)
Function: Can catalyze the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose and trehalose.
Interaction partners:
- Inner membrane symporter YicJ
- Uncharacterized inner membrane transporter YicL
- Putative beta-xylosidase
Sequence:
MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRERTWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAEFKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGETVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSFEVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTSFTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRRLKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNPDACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWNVLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFWSHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLKCRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAGDVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNDQRPDYVWHEGTAFHLFNLQDGHEAVCEVPAADGSVIFTLKAARTGNTITVTGAGEAKNWTLCLRNVVKVNGLQDGSQAESEQGLVVKPQGNALTITL
Protein: Putative glycerol-3-phosphate transporter 4 (G-3-P transporter 4) (Glycerol-3-phosphate permease 4) (AtG3Pp4) (G-3-P permease 4) (O23596)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- F27J15.22
- Amino acid transporter AVT6C
- Probable sulfate transporter 3.3
- Chloride channel protein CLC-b
Sequence:
MAMNSKRKTPPGIALLRRVRGRNWSPKTFRYAILFITFIAYACYHASRKPSSIVKSVLHPDSSTKPPQEHNSDKIYPWPMGNVFVKREIGDIDEVLLHRKSKGWEPFNGKDGTSRLGEIDVAFLACYSIGMYVAGHLGDSLDLRLFLTWGMIGSGFFVGLFGMGYFWNIHAFWFFLVMQMAAGLFQATGWPSVVAVVGNWFGKRKRGLIMGIWNAHTSVGNICGSLIAAGVLEYGWGWSFIAPGFVMSLGGVLVYLFLAAYPEDVGFPDINSNSGKFIKRKRDVEEEEEEVEEDLGTDVEGDGEGSSGSGSGYENKRSVGLLQACMIPGVIPFALCLFFSKLVAYTFLYWLPFYLSQTTIGGEYVSVKTAGNLSTLFDVGGIVGGILCGYISDKFKARATTAAAFMYAAIPAMLVYHSYGGVSQTVNILLMMVAGLFVNGPYALITTAVSADLGTHKSLQGDSRALATVTAIIDGTGSAGAALGPLLTGFLSTLGWQAVFYMLVVGALCAGLLLTRLVIAEIREKLGYVDEEVPASEPLLTDRR
Protein: CG8896 (Q2XXS4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
ITIIAVAACLLLLVADAHAQQQCNWQYGLTTMDIRCSVRALESGTGTPLDLQVAEAAGRLDLQCSQELLHASELAPGLFRQLQKLSELRIDACKLQRVPPNAFEGLMSLKRLTLESHNAVWGPGKTLELHGQSFQGLKELSELHLGDNNIRQLPEGVWCSMPSLQLLNLTQNRIRSAEFLGFSEKLCAGSALSNANGAVSGGSELQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLEQLLVLDLSGNQLTSHHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGAFLPLYNLHTLNLAENRLHTLDNRIFNGLYVLTKLTLNNNLVSIVESQAFRNCSDLKELDLSSNQLTEVPEAVQDLSMLKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIERGAFDKNTEIEAIRLDKNFLTDINGIFATLASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVTTLDASHNRITEIGAMSVPNSIELLFINNNIIGQIQANTFVDKTRLARVDLYANVLSKISLNALRVAPVSAEKPVPEFYLGGNPFECDCSMEWLQRINNLTTRQHPHVVDLGNIECLMPHSRSAPLRPLASLSASDFVCKYESHCPPTCHCCEYEQCECEVICPGNCSCFHDATWATNIVDCGRQDLAALPNRIPQDVSDLYLDGNNMPELEVGHLTGRRNLRALYLNASNLMTLQNGSLAQLVNLRVLHLENNKLTALEGTEFRSLGLLRELYLHNNMLTHISNATFEPLVSLEVLRLDNNRLSSLPHLQYRHSLQGLTLGRNAWSCRCQQLRELAQFVSDNAMVVRDAHDIYCLDAGIKRELELIGNLANGPDCSDLLDASASNISSSQDLAGGYRLPLLAAVLVLIFLVVVLIIVFVFRESVRMWLFAHYGVRVCEPRFEDAGKLYDAIILHSEKDYEFVCRNIAAELEHGRPPFRLCIQQRDLPPQASHLQLVEGARASRKIILVLTRNLLATEWNRIEFRNAFHESLRGLAQKLVIIEETSVSAEAEDVAELSPYLKSVPSNRLLTCDRYFWEKLRYAIPIELSPRGNNYTLDHHERFKQPVSPGMIFRQAPPPPAYYCTEEMEANYSSATTATPSPRPTRPGGAARIVDSMPMPMRPPSEHIYHSIESEYSAYDQHEALSMIPTGLMHQHQQQQLRLHQQQQQQQQQRLLQPQFRAMPQQAIPAPSAPVHLRSGSGLSQASTSTQSTAQASTSAAAAQQQQQQQQQQQQAAGSEAANKN
Protein: Outer membrane protein beta-barrel domain-containing protein (Q73JV3)
Organism: Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
Interaction partners:
- Transcriptional regulator, AraC family
Sequence:
MKIQKKLFIFAVLLMTASLVFAQISMTSYSTQNLFGTDVDDFMNVNEWQNVQPKNIFGFLGYGKTGKGSINLGLAHQFKPFYLGTYFEGQLNGWEKKKEANGNITTYIPAGTASKSNGKLLFGFGNIGIMTDVSYKPDQNKKTEWTEATKTKQTDNLFNLDFNLIAGINLNSNNKLFKISAKLGLESDVGKKTTKVDSKLTKFEDKSKYNLVINAGFSHDFSSKDGITQTVLADLDTKWGIWPTKREVNVVGGVTTTDYKYGELKDILRLTPKYRIAYEPEGKFAFKAEAGLGIGFDFENDYNYTRTVVSSGGDTKAYNAARTYKTTLSLQPELKAAFVYAPVSKFKLNFGLGFNVPSVNWAFEKTETRDASGNVTNTAKGNTLTFNTNDGKFSADSGFTWLITENVIFDANWNIVNNLLKTFSTNLTEGDGINFWNTVNKLVVHNIKFALSVKF
Protein: UBX domain-containing protein 11 (Colorectal tumor-associated antigen COA-1) (Socius) (UBX domain-containing protein 5) (Q5T124)
Organism: Homo sapiens (Human)
Function: May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Rho-related GTP-binding protein Rho6
- Rho-related GTP-binding protein RhoE
- Ubiquitin thioesterase OTU1
- Phospholipase A-2-activating protein
- Transitional endoplasmic reticulum ATPase
- Rho-related GTP-binding protein RhoN
Sequence:
MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ
Protein: Aquaporin NIP1-1 (NOD26-like intrinsic protein 1-1) (AtNIP1;1) (Nodulin-26-like major intrinsic protein 1) (NodLikeMip1) (Protein NLM1) (Q8VZW1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Water channel probably required to promote glycerol permeability and water transport across cell membranes.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Major latex-like protein
- Probable aquaporin SIP1-2
- 2-oxoglutarate
- Putative F-box/kelch-repeat protein At4g22430
- Probable aquaporin SIP2-1
- Calcium-dependent protein kinase 31
- Aquaporin SIP1-1
Sequence:
MADISGNGYGNAREEVVMVNLKDEVEHQQEMEDIHNPRPLKKQDSLLSVSVPFLQKLIAEFLGTYFLVFTGCASVVVNMQNDNVVTLPGIAIVWGLTIMVLIYSLGHISGAHINPAVTIAFASCGRFPLKQVPAYVISQVIGSTLAAATLRLLFGLDHDVCSGKHDVFIGSSPVGSDLQAFTMEFIVTFYLMFIISGVATDNRAIGELAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPALVYGCYKGIWIYLVAPTLGAIAGAWVYNTVRYTDKPLREITKSGSFLKTVRIGST
Protein: Seminal fluid protein 96F (C4NAP6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Seminal fluid protein 60F, isoform A
- GEO13347p1
- Accessory gland-specific peptide 57Dc
- Accessory gland-specific peptide 57Db
- Accessory gland-specific peptide 57Da
- Seminal fluid protein 24Bb
- FI11009p
- Testis-specific Plus3 domain b
Sequence:
MKFLAGYFLLLIGFAVAQKDADSNVNHNVININ