wanglab/gogpt-training-data huggingface dataset:
Protein: Spermatogenic leucine zipper protein 1 (Testis-specific protein 1) (Testis-specific protein NYD-TSP1) (Q9BXG8)
Organism: Homo sapiens (Human)
Function: Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MASSAKSAEMPTISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALRGKMRSASSLR
Protein: Leukotriene A(4) hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Q6NUX4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU361141}.
Interaction partners:
Sequence:
MTPVSDPSSFSSLSKCSTKHLNLIYHVDFDRHVLKGKVALTVEVLEDKFSSLTLDSKDLKISKVSANGQAAKFELGAKHKFKGSPLEITLPFELSRGQHVIVEIEYETSPTATALQWLTPKQTAGKKHPYLFSQCQATHCRTMVPCQDTPSVKHTYYAQVSVPRELVALMSALRDGQEPDPSDSSRVIYRFRQPVPMPSYLIAIVVGALESREIGPRSRVWSEKEYVDEAAYEFAETETMLKTAESLAGPYVWGQYDVLVLPPSFPYGGMENPCLTFVTPTVLAGDRSLAGVIAHEISHSWTGNLVTNRTWEHFWLNEGHTVYIERMIARCMEGEQLRQFKGIGGWKELHESVKQFGANNVLTNLVPNLHEVDTDEAFSSVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQLFAYGSVTTEEWKNYLFTYFKDKVDILNKVDWNAWMHTPGMAPVRPQYDTTMADACTSLCQKWVKAKEADLASFTEADVKQLNSPQLIEFMALLLQEDPLPLSHVKKMGEVYKLNNIKNAEVRFRWLRICVKAQWEEAVPLALKMATEQGRMKFTRPLFTEVYNFSKYSDEAVKTFKEIRGSLHPVTAMLVAKDLKIDG
Protein: At2g03740 (Late embryogenesis abundant domain-containing protein / LEA domain-containing protein) (Late embryogenesis abundant domain-containing protein/LEA domain-containing protein) (Putative cold-regulated protein) (Q9ZPQ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alpha/beta-Hydrolases superfamily protein
- GDSL esterase/lipase EXL6
- Calmodulin-like protein 2
- Probable calcium-binding protein CML33
- Calmodulin-like protein 6
- Probable calcium-binding protein CML34
- Probable calcium-binding protein CML32
- Probable calcium-binding protein CML26
- Embryo-specific protein 3
- Probable calcium-binding protein CML25
Sequence:
MSISGAVLSGLGPSFLISGGKRSGVGGGAMKVGRKNVIIAPQRKKSWVSAAVKGAGNSPNDPKWLDDASEKASGYVKEKGSEVGNVSAQKGQELQNQMERAKDYIFGKAGEAMDSVAENAKRASDFVTEKGKEVKEETTSRTDKAKDFIVEKAGDVKDTAMDMRNKTSKYVGDKATEAKEAILPPKTDA
Protein: Trans-sialidase (Q38D60)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- 30S ribosomal protein S8, putative
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Ribosomal protein S23 mitochondrial conserved domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MLCRTFLRQFRMSGGDMFVEYKVLSRDHRRSIRVEDAIVDPTFKRTVLPLSWLELLRSPSLRLPTGYFVEETVHVSLPNATSNGGKKEARPQKGGFASGSPSVGRNEANAIIAGPVVLYITGQSVPVVLNPYFVPEGTWDMRTRDGELDLRLGMDAIEQCTLFSELRPGGLLYGKLPENPNVRRNESLRATLGRYGMKCDLAESPLVPRPWTRMRYMFIDELQRGPKLTEFVGHNPRNGTPWRFSQNTKYFRIGIWRDTIRRNDMNEGLHAHSSWQKSPQQSVPEVRFLAPYP
Protein: Valine/tyrosine/tryptophan amino-acid permease 1 (Tyrosine and tryptophan amino acid transporter 1) (P38085)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High-affinity transport of valine and tyrosine. Low-affinity transport of tryptophan. Can also transport L-cysteine.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- General amino acid permease AGP1
- N-
- Vacuolar amino acid transporter 5
- Pentafunctional AROM polypeptide
Sequence:
MDDSVSFIAKEASPAQYSHSLHERTHSEKQKRDFTITEKQDEVSGQTAEPRRTDSKSILQRKCKEFFDSFKRQLPPDRNSELESQEKNNLTKSIKSRHLVMISLGTGIGTGLLVGNGQVLGTAGPAGLVLGYGIASIMLYCIIQAAGELGLCYAGLTGNYTRYPSILVDPSLGFAVSVVYTIQWLTVLPLQLVTAAMTVKYWTSVNADIFVAVVFVFVIIINLFGSRGYAEAEFIFNSCKILMVIGFVILAIIINCGGAGDRRYIGAEYWHNPGPFAHGFKGVCTVFCYAAFSYGGIEVLLLSAAEQENPTKSIPNACKKVVYRILLIYMLTTILVCFLVPYNSDELLGSSDSSGSHASPFVIAVASHGVKVVPHFINAVILISVISVANSSLYSGPRLLLSLAEQGVLPKCLAYVDRNGRPLLCFFVSLVFGCIGFVATSDAEEQVFTWLLAISSLSQLFIWMSMSLSHIRFRDAMAKQGRSMNEVGYKAQTGYWGSWLAVLIAIFFLVCQFWVAIAPVNEHGKLNVKVFFQNYLAMPIVLFAYFGHKIYFKSWSFWIPAEKIDLDSHRNIFVSPSLTEIDKVDDNDDLKEYENSESSENPNSSRSRKFFKRMTNFWC
Protein: CD209 antigen-like protein B (DC-SIGN-related protein 1) (DC-SIGNR1) (OtB7) (CD antigen CD209) (Q8CJ91)
Organism: Mus musculus (Mouse)
Function: Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Lymphocyte-specific protein 1
- Intercellular adhesion molecule 2
- Scavenger receptor cysteine-rich type 1 protein M130
- Lymphocyte antigen 75
- Sialoadhesin
- Mannose-binding protein A
- Intercellular adhesion molecule 5
Sequence:
MSDSTEAKMQPLSSMDDDELMVSGSRYSIKSSRLRPNSGIKCLAGCSGHSQVPLVLQLLSFLFLAGLLLIILFQVSKTPNTERQKEQEKILQELTQLTDELTSRIPISQGKNESMQAKITEQLMQLKTELLSRIPIFQGQNESIQEKISEQLMQLKAELLSKISSFPVKDDSKQEKIYQQLVQMKTELFRLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCTEG
Protein: Mediator of RNA polymerase II transcription subunit 3 (Hyper-recombination suppressor protein 1) (Mediator complex subunit 3) (Poly-glutamine domain protein 1) (P40356)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. PGD1/MED3 is also involved in direct repeat recombination.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16630888, ECO:0000269|PubMed:8849881}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 2
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 15
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 1
- Mediator of RNA polymerase II transcription subunit 20
- Mediator of RNA polymerase II transcription subunit 7
Sequence:
MDSIIPAGVKLDDLQVILAKNENETRDKVCKQINEARDEILPLRLQFNEFIQIMANIDQEGSKQADRMAKYLHIRDKILQLNDRFQTLSSHLEALQPLFSTVPEYLKTADNRDRSFQLLEPLSTYNKNGNAVCSTATVVSTNHSAAASTPTTTATPHANPITHAHSLSNPNSTATMQHNPLAGKRGPKSGSTMGTPTVHNSTAAAPIAAPKKPRKPRQTKKAKAQAQAQAQAQAQVYAQQSTVQTPITASMAAALPNPTPSMINSVSPTNVMGTPLTNMMSPMGNAYSMGAQNQGGQVSMSQFNGSGNGSNPNTNTNSNNTPLQSQLNLNNLTPANILNMSMNNDFQQQQQQQQQQQQPQPQYNMNMGMNNMNNGGKELDSLDLNNLELGGLNMDFL
Protein: DNA-directed RNA polymerase RPB2 homolog (RPB2 homolog) (EC 2.7.7.6) (P42487)
Organism: African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV)
Function: Catalytic component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity). Forms the polymerase active center together with RPB1 (By similarity). Part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
Subcellular location: Host cytoplasm {ECO:0000305}. Virion {ECO:0000269|PubMed:30185597}. Note=Found in association with viral nucleoid. {ECO:0000269|PubMed:30185597}.
Interaction partners:
Sequence:
MEPLRPQITYGPIETVDNEELTEADMLSFISAAVNSTGLIGYNIKSFDDLMDNGIPQIVKQMFNVDITYKDQRDHTEIDKLRESVQIQFNFTDVNIERPQHRNYSQGNKINLLPNKARLCGLSYSGPVNLAAEVILTAHYSNGRQEVKRASIPPFQVSTFPIMRGSNRCHTHHLSKTAKKEIGEDPNEPGGYFIARGGEWVVDLLENIRFNTLHIHYHTMQQGNNEIIRGEFISQPGGAFENSSQIIIRYMTTGAITIEINSTKFSKLRIPWYLIFRMFGMTGDDSIIEQVVFDLESNSPVNTFMIEILEKSIHVLDPIFQPVQHEPNREKIIQFLSEKVSKFVSNPSAYKSDENAVQYLNERQLTILDKILLPHMGQTADTRVRKLRFLGLLIHKILLVIMNVFPPTDRDSYRTKRVHGSGVSLAKAFKAIFNTSVIAPIINGFKELLKQTAFEELTQRNIIEAFSAALSKNTASDLNRSMEQSIISGNKTIMVRQRPIVNRVSTQSLERKNLLNTISALRTVNTHNTTNASKQTERADMMRRVHASYPGYICVAQSADTGEKVGMSKQLAITANVCTAGEVLSLKQRLLSDPAIQQLADVSNKDIVRKGLARVFINGEWIGCCTNAFELAQRYRMFRREGKIVHPHTTIYWDSMVDEVEFWLDVGRLTRPLLIVDNNIEKYNQACYKAAEARKKGDKDWEKHKIPFIQNTRFTSQMAKDILAGTLTLEDLVAQGICEFITPEEAENCLVAFSIIELRKHKHDVTRRFTHVDVPQAILGLAALVSPYANCTQPARVTYETNQGRQTGGWYCFSWPYRVDMNRFFQFYNEMPLVKTIAHNYVIPNGLNTIVAYMIYGGYNQEDSVIVSQSFIDRGGFAGTFYREEKVELESDIESFGKPDPLITKNLKPGANYEKLVDGFVPVGTVVKKGDIIIGKVAKIRGEKDELNKYIDRSVMYGFDEPAVVDAVMRPHGPNDEIFGLMRLRYERNLNIGDKMSSRSGNKGIAALALPTSDMPFTEDGLQPDLIVNPHSHPSRMTNGQMIETTVGLANALQGVVTDGTAFLPINVQLLSERLAQEGLRFNGCQKMFNGQTGEYFDAAIFIGPTYHQRLQKFVLDDRYAVASYGPTDALTGQPLDGKRSHGGLRLGEMEHWVLTAQGAMQTIIEKSHDDSDGCISYICRNCGEPAIYNASHPIYKCMNCDVQADIGMVDSRRSSIVFQHEMRAANVNITSVLSPRVFQPA
Protein: VENT homeobox 2, gene 2 S homeolog (Xvent-2B protein) (Q9YH70)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MNTRTNTDKMTKAFSSVEWLAQSSRRSYREKPSKVDQRYSPYPSPSLPSWNSEVSPSSWNNQLSPDPDSTQVSPCPGNAQVSPYSSDSEISLYSHEEEATFHGRDLNTSTPGDNGLHKDTAKYEYHGMVSVPAKTPTTSSNQVASKSGYSTSTDSDYESEASRSSSAAPEGDATMSLSPSDTSDEEGKMGRRLRTAFTSDQISTLEKTFQKHRYLGASERRKLAAKLQLSEVQIKTWFQNRRMKHKREIQDGRPDSYHPAQFFGVYGYAPQPTPVFQHAVQQPYPGYNPLMESMPCTMPYAMHPSAKDSLTPFNSQPFQMLYLPQQHLGQSLAY
Protein: PR domain containing 2, with ZNF domain (A2A7B5)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Forkhead box protein G1
- Calmodulin-lysine N-methyltransferase
Sequence:
MHQNTESVAVTETLAEVPEHVLRGLPEEVRLLPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVRNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEIAAAIEEERASARSKRSSPKSRRGKKKSQENKNKGVRTQAAARKASELDSTSANMRGSAEGPKEEDERPLASAPEQPALLPEVVSQDAVPQVAIPLPACESQPGADGKQEVTDCEVNNMKEEEEEEEEELEEEEEEEELGEDGEEEADMPNESSVKEPEIRCEEKPEDLLEEPRSVPTETSEGSPGATPPPHAPRAREEANGEGLETFMFPCQHCERKFATKQGLERHMHIHISTINHAFKCKYCGKPFGTQINRRRHERRHETGLKRRPSMALQSSEDPDDGKGENVTSKDESSPPQLGQDCLILNSEKTSQEILNSSFVEENGEVKELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGGLLEEPQPPAEQAPPSQNVYVPSTEPEEDGDADDVYIMDISSNISENLNYYIDGKIQTNNSTSDCDVIEMESNSAHLYGIDCLLTPVTVEITQNIKSTQGSVTDDLLKESPSSTNCESKKRRTASPPVLPKIKAETDSDSTAPSCSLSLPLSISTTEVVSFHKEKGVYLSSKLKQLLQTQDKLTPPAGISTAEIPKLGPVCVSAPASMLAVTSSRFKRRTSSPPSSPQHSPALRDFGKQSDGKAAWTDTALTSKKPKLESRSDSPAWSLSGRDERETGSPPCFDEYKISKEWAASSTFSSVCNQQPLDLSSGVKQKSEGTGKTPVPWESVLDLSVHKKPCDSEGKEFKENHLAQPAAKKKKPTTCMLQKVLLNEYNGVSLPTESTPEATRSPSPCKSPDTQPDPELATDSSCSAPTAESPPEVVGPSSPPLQAASLSSGQLPPLLIPTEPSSPPPCPPVLTVATPPPPLLPTVPLPNPSCDASPQQCPSPFSNATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSFSSSSCSSSSPSPPPLSAVSSVVSSGDNLEASLPAITLKQEESESEGLKRKEEAPAAGGQSAVQETFSRNFVCNVCASPFLSIKDLTKHLSVHAEEWPFKCEFCVQLFKGKTDLSEHRFLLHGVGNIFVCSVCKKEFAFLCNLQQHQRDLHPDELCTHHEFESGTLRPQNFTDPSKAHVEHMPSLPEEPAEASREEELNDSSEELYTTIKIMASGIKTKEPDVRLGLNQHYPSFKPPPFQYHHRNPMGIGVTATNFTTHNIPQTFTTAIRCTKCGKSVDNMPELHKHILACASASDKKRYTPKKNPVPLRQTVQPKNGVLVLDNSGKNAFRRMGQPKRLSFNVELSKMSPNKLKLNALKKKNQLVQKAILQKNRSAKQKADLRDTSEASSHICPYCDREFTYIGSLNKHAAFSCPKKPLSPSKRKVSHSSKKGGHTSSASSDRNSSSNPRRRTADTEIKMQSMQAPLGKTRARSTGPAQASLPSSSFRSRQNVKFAASVKSKKASSSSLRNSSPVRMAKITHVEGKKSKAVAKSHSTQLSSKASRSLHVKVQKSKAVLQSKTALASKKRTDRFIVKSRERSGGPITRSLQLAAAADLSESRREDSSARHELKDLSYSLRLASRCASSTAPYITRQCRKVKAAAATQFQGPFFKE
Protein: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase) (P0A6A6)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
Interaction partners:
- 3-isopropylmalate dehydrogenase
- 3-isopropylmalate dehydratase small subunit
- 2-isopropylmalate synthase
- Ketol-acid reductoisomerase
- Dihydroxy-acid dehydratase
- D-malate dehydrogenase [decarboxylating]
- Acetolactate synthase isozyme 3 small subunit
- Pyruvate dehydrogenase
- Probable pyruvate-flavodoxin oxidoreductase
- Branched-chain-amino-acid aminotransferase
Sequence:
MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
Protein: Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.17) (EC 6.1.1.24) (Glutamate--tRNA(Gln) ligase EARS2, mitochondrial) (Glutamyl-tRNA synthetase) (Mitochondrial glutamyl-tRNA synthetase) (Q8MZ14)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLKINPRMLMQQCLRHAHSQVRVRFAPSPTGYLHLGGLRTALYNFLYARHLGGKFLLRIEDTDQTRLVPGASERLVEDLLWAGIEIDEGPGFGGQLGPYVQSQRTEIYSKAIEELLHNGTAYRCFCTERRLDLLRKEALRTRQVPRYDNKCRHLTTSEVDSLLAKGTPYCIRFKLTDHEEPLDDLIYGKVHHNVSDNEGDPVVMKSDQFPTYHFANVVDDHLMGITHVLRGVEWQISTTKHLLLYKAFGWQPPKFGHLPLLVNADGTKLSKRQGDIGIQHFRERGYFPQALVNYVVSAGGGFEHRTNAKQQLLSMQALHEQFHIERVNSHPSRLNPELLDDLNRLEIVQRLSGNESRTKLVNEVQQLVKEAYPQHSNLDLAEEHILDVLNWSSKRLTLLQDLTSSKLSFLWVKPSDFQIKDLTAEQLAHLLQLINAIQDFHKDELNVKLKSFAQKENIKFPLMMKTLRAALSGLKEGPGVAEMMEILGKSVTLERLKEALPKESLHLEEDQ
Protein: Karyopherin subunit beta 1 (J3KTM9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
XACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFADENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
Protein: Functional amyloid chaperone FapA (Fibril amyloid chaperone protein FapA) (Q9I2E8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Periplasm {ECO:0000305|PubMed:23504942}.
Interaction partners:
- Functional amyloid subunit FapB
- Protein activator
- Probable coat protein A of bacteriophage Pf1
Sequence:
MSGSSLRIVVPALLVIVGSVPVSLPAHAADGTIVVQRQVQPRVAYRPSMVPDPHPTVVDTNVSAEVNALANGAASGNTVSRELGDADFAIVTSGSGIRSMILTGSALPGFASQPANPATVQAVGNLGTTHGAGGGAGAGLAGQINGSLKQGLAPLQMLGGGQ
Protein: Metabotropic glutamate receptor-like protein L (Q54U89)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKLIIKNLILLLVSCLYFLSNVSCDQEVHMALLLEGQVDDLGINYEVNQGLAETEALIQRAAKVINDANSYDSTYDNIKSLLDQDNPYNLIITSSESQMSAALDIASDYEDTYFLIFGDMGDKKVPHSKVGTYYFNLVSPHFVLGFIAGGMGKSVGMVVPGPPTENYFTANAFYAGMKYYTSPAGAPNPSLSVVATSSYDDYDTATGAGRILLTKDIDICTQSQTDMTVANMFLNASKWAFGTNGFPQSNIYGNRIIQSVVHNFQVPFYEAATMVMKNTWKNGYNFFGDFNNNFFYLDYYSFLVDPLLKNQTEDLISTIKGGAKPYITNGLTYEKILEQTKLSTGITDLGYYAVPTTEVYTTGSINKTFMAVSILEMAICLIIGIIVIFFFSRNINIIYSTIPYCLTILLGASLIAVAIFLWNLRDLNTQICTSKIWMASLGYNVLIGFIIIKSSLIYFKFKEMVKSKNEKISPIPFGRIVLWFVPLLIIDCVLLIIYSTSGNPGKIDSLGLDGIGRYEYTQNCVNNLTGDIILYIILVFHGLQLLYGCVIAWKTRVIDLEEFIEAHDFATAIYLITFCSFIIVILMVGVTSTSNRNTIISACAIFSSFSCVLIIFGAKFWKIYKPVEDDGLPQIKLKPQKSYSGSGGSGNSSGSKSKKTSAHSSTSGVKSGTSAPTQTSQSAMASINIQNFVNPIEASSRAAAQNDN
Protein: Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (High level kasugamycin resistance protein KsgA) (Kasugamycin dimethyltransferase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (P06992)
Organism: Escherichia coli (strain K12)
Function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Has also a DNA glycosylase/AP lyase activity that removes C mispaired with oxidized T from DNA, and may play a role in protection of DNA against oxidative stress.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Protein ApaG
- 4-hydroxythreonine-4-phosphate dehydrogenase
- Bis
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS9
- Ribosome maturation factor RimP
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein uS10
Sequence:
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
Protein: Actin, indirect flight muscle (EC 3.6.4.-) (Actin-88F) (P83967)
Organism: Drosophila melanogaster (Fruit fly)
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Required for proper formation of indirect flight muscle (IFM) myofibrils.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Adenylyl cyclase-associated protein
- Actin-57B
- Actin-42A
- Actin-87E
- Glutaredoxin domain-containing cysteine-rich protein CG31559
- Flightin
- Myosin heavy chain, muscle
- Troponin C, isoform 1
- FI07231p
- Stretchin-Mlck, isoform U
Sequence:
MCDDDAGALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF
Protein: cDNA FLJ55206, highly similar to Loss of heterozygosity 11 chromosomal region 2 gene A protein (von Willebrand factor A domain containing 5A) (B4DHS6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSSVCDMSFLQKSCITMVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHR
Protein: Apidaecin 3+ [Cleaved into: Apidaecin 3-] (C0HKY0)
Organism: Pimpla disparis (Parasitic wasp) (Coccygomimus disparis)
Function: Antimicrobial peptide active against many Gram-negative enterobacterial and plant-associated bacterial species. Not active against other bacterial species like H.pylori, P.mirabilis, B.pertussis or N.gonorrhoeae.
Subcellular location: Secreted {ECO:0000269|PubMed:7929322}.
Interaction partners:
Sequence:
GKPSRPRPAPIQPRPPHPRL
Protein: cAMP-dependent protein kinase catalytic subunit 3 (EC 2.7.11.1) (Protein kinase DC2) (P16912)
Organism: Drosophila melanogaster (Fruit fly)
Function: Does not have an essential role in development.
Interaction partners:
- cAMP-dependent protein kinase type I regulatory subunit
- cAMP-dependent protein kinase type II regulatory subunit
- Neuropathy target esterase sws
Sequence:
MDLWHIFLERILVACRVSASVFANFGCGLYSSWKLICGDHDSASGLRAGLATPTQRGKATGDNGTTGTPARTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFTFKLGRSNGRSSSNVASSESSDPLESDYSEEDPEQEQQRPDPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF
Protein: Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9) (P07846)
Organism: Ovis aries (Sheep)
Function: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with xylitol, L-iditol and D-sorbitol (D-glucitol) as substrates, leading to the C2-oxidized products D-xylulose, L-sorbose and D-fructose, respectively. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism (By similarity). May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By similarity).
Subcellular location: Mitochondrion membrane {ECO:0000250|UniProtKB:Q64442}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q64442}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q64442}. Note=Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface. {ECO:0000250|UniProtKB:Q64442}.
Interaction partners:
- Aldo-keto reductase family 1 member B1
- Dicarbonyl/L-xylulose reductase
- Xylulose kinase
- hexokinase
- hexokinase
- L-xylulose reductase
- Hexokinase-2
- Hexokinase-3
- Hydroxyacid-oxoacid transhydrogenase, mitochondrial
- Triokinase/FMN cyclase)
Sequence:
AKPAAENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQGRIGDFVVKKPMVLGHEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLGSKPEVTIECTGVETSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVMIKCDPSDQNP