wanglab/gogpt-training-data huggingface dataset:
Protein: Chordin (Q9Z0E2)
Organism: Mus musculus (Mouse)
Function: Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Bone morphogenetic protein 4
- Bone morphogenetic protein 2
- Bone morphogenetic protein 7
- Growth/differentiation factor 7
- Bone morphogenetic protein 6
- Bone morphogenetic protein 5
- Growth/differentiation factor 5
- Growth/differentiation factor 6
- Bone morphogenetic protein 8A
- Bone morphogenetic protein 8B
Sequence:
MPSLPAPPAPRLLLGLLLLGSRPASGTGPEPPALPIRSEKEPLPVRGAAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQERSNLDPQPAGLVFEYPRDPEHRSYSDRGEPGVGERTRADGHTDFVALLTGPRSQAVARARVSLLRSSLRFSVSYQRLDRPSRVRFTDPTGNILFEHPATPTQDGLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLIWQGALAAETFSAILTLEDPLQRGVGGIALLTLSDTEDSLHFLLLFRGLLGGLAQAPLKLQILHQGQLLRELQANTSAQEPGFAEVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYITTRQSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQPGGHMAVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTALCYSGHSARYDRLPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGMPGPQRLLKGFYGSEAQGVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVHIASQCEAGGLRLASEGVQMPLAPNGEAATSPMLPAGPGPEAPVPAKHGSPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCICQRRTVICDPVVCPPPSCPHPVQALDQCCPVCPEKQRSRDLPSLPNLEPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGATGEVHCEKVQCPRLACAQPVRANPTDCCKQCPVGSGTNAKLGDPMQADGPRGCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSPPLSCGSGKESRCCSHCTAQRSSETRTLPELEKEAEHS
Protein: Metallo-beta-lactamase NDM-8 (NDM-8 metallo-beta-lactamase) (M1VE66)
Organism: Escherichia coli
Interaction partners:
Sequence:
MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMGALHAAGIATYANALSNQLAPQEGLVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR
Protein: Tabersonine 6,7-epoxidase isoform 2 (EC 1.14.14.-) (Cytochrome P450 71D347) (A0A343URW7)
Organism: Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
Function: Component of the monoterpenoid indole alkaloids (MIAs, e.g. echitovenine, tabersonine, lochnericine, 19-hydroxytabersonine and horhammericine) biosynthetic pathway; MIAs are used in cancer treatment and other medical applications. Cytochrome P450 catalyzing the conversion of tabersonine to lochnericine.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:29934299}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MEFVVSPFAFLIFFFILLKMIAKNFKNPKKNTKPLPPGPKKLPIIGNLHQLGGGLAHHILRDLSQNYGPLMHLKIGELSTIVISSTEMAKQVFKVHDIHFSNRPSHILVFKIVSYDYKDIVLSQYGNYWRELRKVCNLHLLSPNRVQSFRFIREDSVLNMMKSISSNEGKVVNLSEMILSLIYGITARAAFGVWSKRHEEFIRLESEIQRLATTFVLADMFPSIKILGALSGLRYKVEKVHKKVDEILEDILKEHRNNNISIEKEEEEEEENNGGKKDLVDVLLDIQKNGEMETPFTDQHIKAIIFDMFSAGTLTSTIAVDWAMAEMMKNPRVMKRAQEEVRNVYNGIGNVNESKLDELKYLQAIIKETLRIHPGTPIVHRETREECEINGYRIPAKARVMVNAWAISRDPNYWPDPDSFKPERFLGSEVDFKGTHFEYTPFGAGRRICPGISYAIANIQLPLAQLLYHFDWKLAGGMKPEELDMAEILGTAAQRKEDLLLIPNSHSCSSLKQQV
Protein: Nuclear pore complex protein NUP160 (AtNUP160) (Nucleoporin 160) (Protein SUPPRESSOR OF AUXIN RESISTANCE 1) (Q9C811)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Contributes to the transfer of mature mRNA from the nucleus to the cytosol. Required for both R gene-mediated and basal disease resistance. RNA export seems to play a critical role in stress responses and regulation of plant growth and development. Required for proper expression of factors associated with auxin signaling.
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:17030626, ECO:0000269|PubMed:21189294, ECO:0000269|PubMed:22902705}; Peripheral membrane protein {ECO:0000269|PubMed:17030626}; Nucleoplasmic side {ECO:0000269|PubMed:17030626}. Nucleus, nuclear pore complex {ECO:0000305|PubMed:17030626}.
Interaction partners:
- Protein SEH1
- Nuclear pore complex protein NUP107
- Nuclear pore complex protein NUP155
- Protein transport protein SEC13 homolog B
- Nuclear pore complex protein NUP205
- Nuclear pore complex protein NUP85
- Nuclear pore complex protein NUP88
- Nuclear pore complex protein NUP35
- Nuclear pore complex protein NUP96
- Nuclear pore complex protein NUP54
Sequence:
MEENRRNPSAGMEVPVAGGGNVVKWIEISVPSPSVSSSSIGANSSEDNECVQLPLSEDYASSSVIGEPSISFVWRINKTSPNALELLQLSAKSGFPITGLRFVFAQTLSPFAFVYADEGGDSGRLVYFLYSLTPSGVVYVLKLSNTLAYKSGSVFPLDHLIHLDVRPYLNESRVTSVAASPGFIFLGRSDGCVSCFQPIVYFQKSSGFHQELRDDTGFGRLGTVVAAVQDLFISEVHGRNYLCVLHADGALRVWDILTYSRVLCQSIAAKNLEGVMCVRLWLGKADYDSGIIPLAVLYRKSMNDSMDVITVYGLHFSSAEGIALSLDSGLQNIPLEEGELRDVRFTSDKIWTLKANELTSYMLCQKSSTMEAQSYTLQEDYISEQLFLSSRSSSHDLLLTTHSLFSSAKDQIMGFISSIFLRRLLCPGIFHNVALRLTLLDHNKNWTDSEFQSLSLDELTSEILLLVEHEVTAETSISVFHWWKNFCTSYLHHWCSNNEPRTLLVQSDVIGLVRNNSVSLFFRLENAEHSLGGSSSEHSNLTSLDLGVSHSDHEILAEVLRCTSKISKQWGGAPYAMYYESITGRPIISSDEIVPRLVNILESGYSTTIGQRTWSDLGADRAWEKELEAHKNLRTFSIDMLLSLSALCQRAGSWEKVFTIMEHYLQYLVPKKSMQKNDGEALSDICSSILVQATSQFVKVMFESAFDIFLLISYLLNIAGQVNMSQQDICKLRLELLPMIQDIVSEWLIILFFVTTPAESTSMEDFSLKLSSLQIDSSIDKRSWNAMLGKCGFSLAFILLFSDRSCIVDGRFNLRYLPSSQIITSLVQNFISWIRYSKTGDDSSSLLRRSTELSLRLIRNGQSDAVERILVVVEASLRGEKTFGCSQDTSGDWCLLQHLRGCCLLDQVQRGASGILRERKIIDAIRCFFRASSGEGSWKALHSLSKEAGFSPATTGPSILDGSTSSAAWKLHYYEWAMQIFERYNISEGACQFAYAALEQVDDAYNFIEMTEEFDPTKAATYTRGRLWANVFKFTLDLNLLNDAYCAIISNPDEEIKRICLRRFIIVLFECGKTKILSDGHLPFIGLTEKITQELFWKAGRSDIMMKPNPYKLLYAYEMRRHNWRMAASYMYQFSARLRSEGACKDYKHMSLVLQERLNGLSAAMNALALVHPGYAWIDPVPEETTRYPVKKARRAEEEQLRSNDQPKGEKSCIDIEKLQNEFVFTTAEYMLSLKNFGWTYSGLEKPPSDLVDLLVQANLYDMAFTVVLKFWRGSALKRELEKIFENMAIKCCPAKGTLWSSPNLMLTSNDEEVTHSPDRSPADQGSKLAGDWEILEVYLKRYIDIHARLPVSVASTLLQADSCIELPLWLIQMFKDGQKEKALGMAGQEASPASLFQLYVDYGRLTEATNLLLEYMESFASSKPAEVLKRKKVSGVWFPYTTVERLWWELEKTMNSGRMVEQCHKLKEQLHHALLNHLKLLKVDSNDAVSSATG
Protein: Spt23p (A0A1D8PIM6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Acyl-CoA desaturase
- AAA family ATPase
- Ubiquitin fusion degradation protein 1
- E3 ubiquitin-protein ligase
- Doa1p
- Ubiquitin thioesterase OTU
Sequence:
MTDPLTFLDEFNEFFYFPEDNDTFAPNEIGKLKFGSKINATPKSIEVPSSYLDFSPETMNNLPYRLSISGLPSFSRVETQIKMNLTINAPFTNHYVHITPDLISKKKLCLEEPYSNLDDNIKKHILEFDAYILTQSNKSCAVCPRCIKREQKRASRSKAGEEKSAVWDCDVERKAIIINNKEIIAFQSGVLELSARIICYCRHHKESEGFKLLIVLKNHLGQVVAKQISSPIMIMDRKKNLKDSAPSSSANLVELDKKKLSISDSDNEKLMTNQFVQLSPNSLDESASEALATTDYETRGVKRKKLSVDDSFNTTSNPMYNGFSGYSPMSNSDTNTSAISQSFSGPTISKPSSAQFSIGFSPISQPQFPSQFQSQTQLLQQQQQQQQQQQQQQQQQQQQQTVPSIQKIIPAQGSIRGGIEVTILGFNFRPGLSIKFGANQALATHCWSETTIVTYLPPAAQPGQVLVTFENQDNDNVGGPQQQQVFTYTDDTDRQLIELALQIVGLKMNGKLEDAKNIAKRIVGTDNNNNNNNNNNSSNTNTNTSTNSNSPADNENDNNNTNNNTTAGAAAPGAAPGNTVTSTNSNTSSSFENDEKSMAKLNKLVEFFESRTNNQDDLEKWSSMKTSEIFGDQEEEYFADSEVVPSYKSIFPNGGNANNTKLIAEPTPEADAGATSDSSEDMVVTYINHPRKSMKNDKMLLFFWIPALVIMLFTFFMVYVVGYQLNDYSIVEKMLNCTSLLR
Protein: Germ cell nuclear acidic protein (Acidic repeat-containing protein) (Germ cell nuclear acidic peptidase) (A0A0R4IWG9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May play a role in DNA-protein cross-links (DPCs) clearance, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96QF7}. Nucleus, PML body {ECO:0000250|UniProtKB:Q96QF7}. Chromosome {ECO:0000250|UniProtKB:A0A1D9BZF0}. Note=Co-localizes with SUMO2 at PML bodies in all interphase cells (By similarity). Localizes on condensed chromosomes in spermatocytes in G2 and M during meiotic prophase (By similarity). {ECO:0000250|UniProtKB:A0A1D9BZF0, ECO:0000250|UniProtKB:Q96QF7}.
Interaction partners:
- Cingulin a.
- Lens epithelial protein.
- FERM and PDZ domain-containing 1a.
- Pre-B-cell leukemia homeobox-interacting protein 1b
- Protein S100-A11
- Ubiquitin-conjugating enzyme E2 K
- FAD synthase
- Cholinergic receptor, nicotinic, alpha 9.
Sequence:
MDPGTLSLFQRVSTKLGWDRDGGLDDAEEKLRKSLKKTRRPALASSDSSTGPAQRLELSDSDNSSGKENRSQEEHILLTSDDEDFEKFLASKATPKSTFKQSASSAQKPREPVPVLSSESDNEFELFLNRVKTPKAKVQPQSMSSSDESLKHFIVDSMSSDDDFVTEKKPSIYKGKAKTVKTPKSVQKTKKPAPSLCNSPVFLSDSDDDCNIVIKSTWRTRHSRPPSDEHQATSKDREETEKPRVPQPTITVKSHTSRDDTCSSEEEFQSLLDRVRQNLGGRTSASPMPSAEPKPQRPCLSTPSATGRKTGSQVPVKDSPVIHTPVQQMPSSRPVLSHTEPRALPNSRVVVCKTPGCFLQSLSAPGSVYCRSFKQNKDELTSKLYQLYNTSVFDSQLPVDMSVTWNNKMRKTAGYCISGQERGTGKRYARIELSVKVCDSADRLRDTLIHEMCHAATWLINNVRDGHGPFWRLYARKAMLAHPELPMVSRCHSYDINYKFQYQCNRCKNTIGRHSKSLDTTKFVCALCTGQLVLLTPSKPRAPTPFATFVKENYGSTKQELTGQSHAEIMRKLSADFASKTRLSQS
Protein: Olfactory receptor 2C1 (OLFmf3) (Olfactory receptor 2C2) (Olfactory receptor OR16-1) (Olfactory receptor OR16-2) (O95371)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P23275}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Olfactory receptor 2L13
Sequence:
MDGVNDSSLQGFVLMGISDHPQLEMIFFIAILFSYLLTLLGNSTIILLSRLEARLHTPMYFFLSNLSSLDLAFATSSVPQMLINLWGPGKTISYGGCITQLYVFLWLGATECILLVVMAFDRYVAVCRPLRYTAIMNPQLCWLLAVIACLGGLGNSVIQSTFTLQLPLCGHRRVEGFLCEVPAMIKLACGDTSLNQAVLNGVCTFFTAVPLSIIVISYCLIAQAVLKIRSAEGRRKAFNTCLSHLLVVFLFYGSASYGYLLPAKNSKQDQGKFISLFYSLVTPMVNPLIYTLRNMEVKGALRRLLGKGREVG
Protein: FK506-binding protein 1A (FKBP) (FkbA) (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) (Q6KBA8)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Serine/threonine-protein phosphatase 2B catalytic subunit
- Calcineurin subunit B
- Calmodulin
- Uncharacterized protein
- Peptidyl-prolyl cis-trans isomerase pin4
- Peptidyl-prolyl isomerase cwc27
- non-specific serine/threonine protein kinase
Sequence:
MGVEVQRISPGDGKNFPKPGDTVSIHYTGTLADGSKFDSSRDRPGTFVTQIGVGRVIKGWDEGVLQLSVGEKAKLICTPDYAYGARGFPPVIPPNATLTFEVELLKIN
Protein: Methyl-CpG-binding domain-containing protein 2 (AtMBD2) (MBD02) (Methyl-CpG-binding protein MBD2) (Q8LA53)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcriptional regulator.
Subcellular location: Nucleus {ECO:0000269|PubMed:14605234, ECO:0000269|PubMed:15805479}. Note=Not present in chromocenters and the nucleolus.
Interaction partners:
- Heptahelical transmembrane protein 1
- Methyl-CpG-binding domain-containing protein 5
- Methyl-CpG-binding domain-containing protein 7
- Methyl-CpG-binding domain-containing protein 6
- Methyl-CpG-binding domain-containing protein 8
- Methyl-CpG-binding domain-containing protein 11
- Methyl-CpG-binding domain-containing protein 10
- Inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Methyl-CpG-binding domain-containing protein 9
- Methyl-CpG-binding domain-containing protein 13
Sequence:
MSMSQSRAVQRSSSPNEDRGENQLVVYDLKGNDDTEEEVLPVQSQPLSSRTQCPSIGAFTVQCASCFKWRLMPSMQKYEEIREQLLENPFFCDTAREWKPDISCDVPADIYQDGTRLWAIDKPNISRPPAGWQRLLRIRGEGGTRFADVYYVAPSGKKLRSTVEVQKYLNDNSEYIGEGVKLSQFSFQIPKPLQDDYVRKRPARLLDSIDNTNTPVAKEANPLAWISPDDHISLQLGTPTESGLNNSHYQPSKKKKTSTLSIFGSNDELADR
Protein: Mitochondrial fission 1 protein (B7YZT2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Functions downstream of Pink1 and upstream of Drp1 to regulate mitochondrial fission.
Subcellular location: Mitochondrion outer membrane {ECO:0000255|PIRNR:PIRNR008835}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- dynamin GTPase
- TBC1 domain family member 15
- Dynamin
- Transmembrane GTPase Marf
- Transport and Golgi organization protein 11
- Gdap1, isoform A
- Peroxin 11
- Serine/threonine-protein kinase Pink1, mitochondrial
- Dynamin-like GTPase OPA1, mitochondrial
- Transmembrane GTPase fzo
Sequence:
MEDLLNEVVPQEDLERFEKKYHHELELDGEVTTDTKFEYAFCLVRSRYTNDVRKGIMILEELARTHPDGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIESNDQVRSLEEYIKKEIDKEVAKGMVVAGGAALVLGGILGLGIAMARNKQKREK
Protein: Lysine-specific histone demethylase 1 homolog 2 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2) (Q9LID0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin of the floral repressor FLOWERING LOCUS C (FLC) and the sporophytically silenced floral repressor FWA. Seems to act in partial redundancy with FLOWERING LOCUS D (FLD) to repress FLC expression. Required for cytosine methylation of FWA. Controls primary seed dormancy by regulating DOG1 and abscisic acid signaling-related genes.
Interaction partners:
- Protein LHY
- Protein CCA1
- Histone deacetylase 6
- WD-40 repeat-containing protein MSI4
- Histone H3-like 2
- Histone H3-like 5
- Histone H3-like 3
- Histone H3.3
- Histone H3-like 1
- Histone H3-like 4
Sequence:
MNSPASDETAPRRNRRKVSRKNYDENAMDELIEKQLGGKAKKKYRTKQDLEKETETEALIALSVGFPIDELLEEEIRAGVVRELGGKEQNDYIVVRNHIVARWRGNVGIWLLKDQIRETVSSDFEHLISAAYDFLLFNGYINFGVSPLFAPYIPEEGTEGSVIVVGAGLAGLAAARQLLSFGFKVLVLEGRSRPGGRVYTQKMGGKDRFAAVELGGSVITGLHANPLGVLARQLSIPLHKVRDNCPLYNSEGVLVDKVADSNVEFGFNKLLDKVTEVREMMEGAAKKISLGEVLETLRVLYGVAKDSEERKLFDWHLANLEYANAGCLSNLSAAYWDQDDPYEMGGDHCFLAGGNWRLINALAEGLPIIYGKSVDTIKYGDGGVEVISGSQIFQADMILCTVPLGVLKKRSIKFEPELPRRKQAAIDRLGFGLLNKVAMLFPSVFWGDELDTFGCLNESSINRGEFFLFYAYHTVSGGPALVALVAGEAAQRFECTEPSVLLHRVLKKLRGIYGPKGVVVPDPIQTVCTRWGSDPLSYGSYSHVRVGSSGVDYDILAESVSNRLFFAGEATTRQHPATMHGAYLSGLREASKILHVANYLRSNLKKPVQRYSGVNINVLEDMFKRPDIAIGKLSFVFNPLTDDPKSFGLVRVCFDNFEEDPTNRLQLYTILSREQANKIKELDENSNESKLSCLMNTLGLKLMGANSVLDTGGALISVIANARRGRSRSHVVAGQCNLPLNPLHFN
Protein: 2' cyclic ADP-D-ribose synthase AbTIR (2'cADPR synthase AbTIR) (EC 3.2.2.-) (NAD(+) hydrolase AbTIR) (EC 3.2.2.6) (TIR domain-containing protein in A.baumannii) (AbTIR) (A0A009IHW8)
Organism: Acinetobacter baumannii (strain 1295743)
Function: NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide. In addition to ADPR, also generates a cyclization variant of cyclic ADPR (cADPR), termed v-cADPR, for which the cyclizing bond is unknown.
Interaction partners:
Sequence:
MSLEQKKGADIISKILQIQNSIGKTTSPSTLKTKLSEISRKEQENARIQSKLSDLQKKKIDIDNKLLKEKQNLIKEEILERKKLEVLTKKQQKDEIEHQKKLKREIDAIKASTQYITDVSISSYNNTIPETEPEYDLFISHASEDKEDFVRPLAETLQQLGVNVWYDEFTLKVGDSLRQKIDSGLRNSKYGTVVLSTDFIKKDWTNYELDGLVAREMNGHKMILPIWHKITKNDVLDYSPNLADKVALNTSVNSIEEIAHQLADVILNR
Protein: C3H1-type domain-containing protein (D6XKD1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSFSMNTVTHSPHSLGSQHNVMTASPFVTPAYVDALDHLSTKLRIPGSAVEPTNAMYDDGLVPGVCRLYMEGRCRQGSRCFQVHANPEVVEKLRQEALEQPTCCFFHGAPCTSSGLPLNLQVNVGGTSITLPRMNSTNCLWSAYAERGDSTLDLPREKVCREHRRGLCRFGEECGFLHICREIAFVGEDASSTGSGLHHSRTSASASPLGSGRKRQVPNSSFGSPPFMQSTSSRDSQCSRKRSFDPNAPDWCNGGYPQRGGRYADDGGVGFFPPQANSCPPAANYPYWPPYGDMTHVHYGHGLSYSNSYMGPGMEQQHPHSFSRTCQSFSHHQVCENVGAGASMFGGPLLRPLANAPRRNTGSVRHNPYGATSLGQ
Protein: Antigen 5 like allergen Cul n 1 (Ag5 like allergen Cul n 1) (Allergen Culn1) (Antigen 5 family protein) (Cul n 12) (B9URJ1)
Organism: Culicoides nubeculosus (Biting midge)
Subcellular location: Secreted {ECO:0000305|PubMed:19523070, ECO:0000305|PubMed:20537727}.
Interaction partners:
Sequence:
MIKKLSIVILFSCISFVLSTNFCNKELCKRQNGPQSFTYLKHIGCRHTGKNANTCPRDAKILPMSTKRKNLILKVHNRLRNKVALGKLPGFPKAARMPILRWDDELAYLAELNVKQCKMEHDQCRNTDKFKYAGQNLAYTMGTPQKNAVRIKKLIRAWFKEHENATASFIDKYRDHPQGRVIGHFTAMIQDRTDTVGCAILRHSGNKYFFWPVIMVLQI
Protein: Nogo receptor homolog 1b (Reticulon 4 receptor-like 2b) (Reticulon-4 receptor-like 2b precursor) (Q6WZD1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTTRAAARSARASNTLTFKSGLTLWLVIWLLACRCAPGQACPRLCVCYHMPMTVSCQSQNFTSVPAGVPYDSQRVFLQNNRITELRADSFGFETQVLWLYSNNITWIEAGAFSNLRVLEELDLSDNPSLRRLDGGAFRGLERLQSLHMHRCHLTELPADLFHKLYSLQFLYLQENQLTNLPDGLFSDLVNLTHLFLHGNRIRTVSENAFRGLVNLDRLLLHDNRIRQVHRRSFRDLGRLTILYLFNNSLQELPGQALRDTSSVQFLRLNGNPWTCGCEARSLWEWFRKARISSSDLTCSSPAPRKGQDLRFLRELDFALCPLPDPGSMAGTTTTTFSTKTRWWFSKNKPASSSKSHFHKSSETLKAFPFNSGKNPSSSSTSFSSKYDLTAEEAALPKLEPEEYWANYGNEDAASVRCFELECPPGYDSPILPSSSSSSLLSFLSLTALTLSFHLLFG
Protein: Pectinesterase QRT1 (PE QRT1) (EC 3.1.1.11) (Pectin methylesterase 62) (AtPME62) (Pectin methylesterase QRT1) (Protein QUARTET 1) (AtQRT1) (Q9FM79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Pectinesterase required for cell type-specific pectin degradation to separate microspores.
Subcellular location: Secreted, cell wall {ECO:0000305}.
Interaction partners:
- Polygalacturonase QRT2
- Polygalacturonase QRT3
- Plant intracellular Ras-group-related LRR protein 1
- Plant intracellular Ras-group-related LRR protein 9
- Calcium uniporter protein 1, mitochondrial
- Transmembrane protein 18
- At5g17340
- DNA mismatch repair protein MSH5
- Meiotic recombination protein SPO11-1
- E3 ubiquitin-protein ligase CCNB1IP1 homolog
Sequence:
MKVEAFIPAVLLLCFGVMLCLKSSCALQIGNNNELKNYISWEDLRVVEDGRIERSFSIKENSNWVTTNANANANATNVRRVIVVDKNGGGDSVTVQGAVDMVPDSNSQRVKIFILPGIYREKVIVPKSKPYISFIGNESYAGDTVISWSDKASDLGCDGKELGTYRTASVSIESDFFCATAITFENTVVAEAGEQGRQAVALRIIGDKAVFYRVRVLGSQDTLFDDNGSHYFYQCYIQGNVDFIFGNAKSLYQDCDIHSTAKRYGAIAAHHRDSETEDTGFSFVNCDISGTGQIYLGRAWGNYSRTVYSNCFIADIITPVGWSDWKHPERQRKVMFGEYNCRGRGAERGGRVPWSKTLTRDEVKPFLGREFIYGDQWLRL
Protein: LP19469p (Q5BI79)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
EREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIKALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPQDIDDAPKPNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI
Protein: Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein homolog) (Q80Z25)
Organism: Mus musculus (Mouse)
Function: Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:20230748}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:24089205}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:O75665}. Nucleus {ECO:0000250|UniProtKB:O75665}. Note=Localizes to centriole distal ends and to centriolar satellites (PubMed:20230748, PubMed:24089205). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (By similarity). {ECO:0000250|UniProtKB:O75665}.
Interaction partners:
- Nuclear distribution protein nudE homolog 1
- Serine/threonine-protein kinase PLK1
- Pericentriolar material 1 protein
- Cortactin-binding protein 2
- Serologically defined colon cancer antigen 8 homolog
- Centrosomal protein of 290 kDa
- Centrosomal protein 20
- Aurora kinase A
- F-box/WD repeat-containing protein 1A
- BBSome complex member BBS4
Sequence:
MAQSNMPHKSDVLSQDELRKKLYQTFKDRGVLDTLQTQLRNQLIHELMHPVLSGEVKPPSISVEGSALLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKIFTMQDLLQLIRINPSSSLYKSLISGFDKENKKGFLMSFLKELAEYYQAKESCDAETQTSTTFPSQVSLAEKFQLIDAQFADGFPHRSKLESLETKLNEYKKEVQHQLQVEMCHKLKYFREAEITKVKMEERRKYEKELAEFQNEFERTCQAKNEALISQEKNSLERIKKHREMESKEIYAQRQLLLNDIALLRGREAELKERIETFELTQKLQEEKIKSEAEALERREQNLKNIEDTYDQKLKTELLKYQLELKDDYITRTNKLLEEERKNKEKTIHLQEELTVINSKKEELSKSVKHMKEVELELESVKAQFLAISKQNHLLNEKVREMSDYSQLKEEKVELQAQNKLLKLQLEETRNENLRLLDRITQPPPELVIFQKELQKTEKAMELEHKDFETHRQALEKQLQSEIENSAQLRTQIAEYDASVKRLTVQVAELKSQLKQTQIALENEVYRNPKHSLIHSLSGLLLSGKMAPHSEDKSGDFLNVPLEQNKVIAGAVMSRVPPYVNTATEASSPESDFEFIASSTKAKVRELEQEAERLEKAFRTYYQRATQNPSTSPQPAKSPPSVNSVAALRSIASSSMDRPVSAEDRVVSEQPLGDMLKEEMSDMSKAFMGSVVSRPRRTSSSTRLSSTPHPKSRRSLDNEMYLEGLGRLHMTSSSPLLDRVSASPAASPSPCPERTAQASPVPSRHSFSGLPEQNACLYQRQTETQDKSELSNVDKQSLKDEKFEPPFRWNKTEQFEAEGLHPAGDMPGIDFAVATQSSRLISYDYPSAVQSQTGEQDEQELWELHMKERRQREEQRHNERQEALERERRELGKLEQERRMIEESLKMEMEEELEKSVQDQKDKSAHCENTLEKYMKIIQQRQEESNADKSSKKSGKECSLVDMMMPSDKDESSPGFSHEEPDDMW
Protein: Glutamate dehydrogenase 1, mitochondrial (EC 1.4.1.3) (Q70PJ7)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
SFPIKRDNGEWEVIEGYRAQHSQHRTPCKGGIRYSTEVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINVKNYTDNELEKITRRFTIELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYANTMGHHDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEAAYMSQLGLSPGFTDKTFVIQGFGNVGMHSMRYLHRFGAKCVGVGEMDGNIWNPNGIDPKELEDYKLQHGTIVGFPNSTPYEGSILEAGCDILIPAASEKQLTRNNAHKIKAKIIAEGANGPTTPDADKIFLERNIMVIPDMYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGAIPVVPTSEFQARIAGASEKDIVHSGLAYTMERSARQIMRTANKYNLGLDLRTAAYVNAIEKVFKVYNEAGLTFT
Protein: Carbonic anhydrase 14 (A0A8I6AM42)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
EFFFQFLDLNSTSQSTRGLPFLLEAGHHWTYEGPHGQDHWPASYPECGGNAQSPIDIQTDGVIFDPDLPTVQPHGYDQLGTEPLDLHNNGHTVQLSLPPTLHLGGLPRKYTAAQLHLHWGQKGTLKGSEHQINSEATAAELHVVHYDSESYGSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSHLHEVRYKDQKTSVPPFNVRELLPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEEDPSEPLVQNYRVPQPLNQRTIFASFIQVGPLYTTGEMLGLGMGISAGCLCLLLTIYFIAQKIRRKRLGNRKSVVFTSARATTEA
Protein: Snaclec purpureotin subunit beta (P0DJL3)
Organism: Trimeresurus purpureomaculatus (Mangrove pit viper) (Cryptelytrops purpureomaculatus)
Function: Snaclec that induces platelet aggregation without any cofactor in a dose-dependent manner. Its platelet aggregation effect is blocked by echicetin, suggesting it is a GPIb-binding protein which binds to the same or a closely related GPIb site on platelets as echicetin.
Subcellular location: Secreted.
Interaction partners:
Sequence:
DCPSDWSSYDLYCYKVFQQRMNWEDAEKFCRQQHTGSHLLSFHSSEEVDFVVSKTLPILKADFVWIGLTDVWSACRLQWSDGTELKYNAWTAESECIASKTTDNQWWTRSCSRTYPFVCKLEV