wanglab/gogpt-training-data huggingface dataset:
Protein: Putative glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (Putative D-hexose-6-phosphate mutarotase) (Unknown protein from 2D-page spots T26/PR37) (P39173)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Phosphoglucomutase
- Glucose-6-phosphate isomerase
- PTS system glucose-specific EIICB component
- Glucokinase
- 6-phospho-beta-glucosidase AscB
- 6-phospho-beta-glucosidase BglA
- 6-phospho-beta-glucosidase BglB
- PTS system glucose-specific EIIA component
- 6-phospho-beta-glucosidase
- PTS system maltose-specific EIICB component
Sequence:
MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQGAHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLPWTLKSHHEDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCSVINDEALNRIIAVGHQHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQKVTKEKPAHLAQSIRVAKR
Protein: MIP12971p (F0JAQ8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFAGIRKRLARKQNEKDCDEDDKEDVLDSMPPPPNYIQISQGRIQLVHQPRTPVESEAGTLSLERHGGSISGSGGCDKDVLEKRMIEVEGALLRLQEQFQKSQCGSPTFEKELREQIENMNRIMKSKERKQMQTCRDHKALQTRFARQESLLQSMQQENRSLLTRIRQYEHCLDDVMRKVVDAIVAEDNLREEVSMLKGRVRDLEAQNAALSASPVKGRDEGYCTMSSGQPQPSNGHLEDLPEEPEQWLLPAEPCSTEMEDWSMSQEELAVMTFDDERDPHHPHLQQQRRKRDHDWLWPSSDFINSTTVETDSVADGITQLLQQKIVYSEDEEVACTDFTNDFYKLVNIRSNSSRSLYSYLEGETDDEDEDDDDGEDSSISESQVGPAGRISPTPSEAGRAQLTSCSSSETDELSASQAKKDEEPDYAVIDECRRRVSDIEIEDVPMIVSSTPMKPLDEQQCIAQIIKSELRRPPHVLVKSKSVLEDQEPSCILRHNQRRELESTVVCSDSISCAMMNKLAKEVVPPAPGMVTKLKERMLLRQASTPPTASSWRRSNGWKRVTSPVHPPVAVSPKKKAAKSTEPPKSCLPKAQPTRIPTSIHSSVSSSSSMSSSCSPSPSSPSPQSPQQRSPGQQTQQQQQQQQQRKSKIPPPVPVRRSYAS
Protein: MADS-box transcription factor 1 (O42954)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as a transcriptional activator with a role in the regulation of mitosis. Regulates septation and the periodic transcription of cdc15.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
Interaction partners:
- Fork head protein homolog 2
- Forkhead protein sep1
- Serine/threonine-protein kinase plo1
- Mitogen-activated protein kinase sty1
- MADS-box transcription factor pvg4
- Mitogen-activated protein kinase spm1
Sequence:
MDINPPPSTAPSSPRRSIQRISDAKNKALTFNRRRLGLIKKAHELSVLCDAKVVVMIFDSKNACHVYSSEEPEEQRDALLQKFLNKDFVTVDPLRNINPNIPSDESLHNWRPKDKRIASVTTYSAQPSNNCSSATDSENDFQSFTIKSSTTYHTTPTTASENKKIESITIPDHASVYNDLPLSPTVKHSFVSPVSGDYSDSPLEPSSSSSFSVPPESLNPTLSFQHNDVPQTDNFIPFLTPKRQAYGQSSSRADRSSVRRSQSFKNRRNGKPRISRLHTSHASIDGLTDFIQSPSSGYLDPSSTPITPLDSAINQITPPFLPDNLGQENRGELYSHDNPTSMVYEHPKFDELPNGFIDTHELNILSRSFTASPNQILRESNMVNQDSFTDNPVDATWDALIGTTQIDLDLDYERSSIPSSTIPADQLKDGVPTNSVYRNNMVDHNLYPSLNIERNAP
Protein: Amino acid transporter, putative (Q57WK7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MTNQSSGGNDRGRRDTDPFAHAGDVKLSSDAIALDVTQKGQDDVVKEVKPSLFAVLLEKFIPHGGLWSCALNLASATLGAGICSLPTGFNLSGIVMSCIYLVCVAVGTVYSLNLLAKVAVKTGSRNYGEAARMVMGPLTGYYAAALMIAMCFGGNVAYIIIIGIILKAVLNRDSVPEYLKSESGNRLMTFMVWLVIILPMCIPKRVNSLRHLSFVGVIAIAYFAFFIVGHSINKIINEGVADDIVYMRTGNSALDGLSLFLFSFICQSNAFEIFREMKHRSPQRFTIYGIVGVVMCAVLYFLVGLFGYLEFGGKSVDTVLSLYDPGENVALAIAYIGIAIKITVAHALHSIPIRDGLYHCVGWHVDTVPYWKHVVVVVTINFTSLIIGLFIPKASTVFGLVGAFCGGHIGLVLPPLFYMYSGGFTREKVGNIDFFGTYLLLFVGVVAVVFGTVTTIAGALS
Protein: Entomoglyceroporin 4, isoform A (Entomoglyceroporin 4, isoform B) (Entomoglyceroporin 4, isoform D) (RH68439p) (Q6NR72)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNWIYWLAPLSSSAITAYAYKVVFRREVVEAEITSNEKLRQLEDVQLS
Protein: Casparian strip membrane protein 2 (AtCASP2) (Q9CAX3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21593871}; Multi-pass membrane protein {ECO:0000269|PubMed:21593871}. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain.
Interaction partners:
- CASP-like protein 4C1
- Protein trichome birefringence-like 15
- Proline-rich extensin-like family protein
- Ultraviolet-B receptor UVR8
- Transcription factor MYB36
- Proline-rich extensin-like family protein
- COBRA-like protein 10
- Pectin acetylesterase 3
Sequence:
MKNESTFIDVPAESSSAMKGKAPLIGVARDHTTSGSGGYNRGLAIFDFLLRLAAIVAALAAAATMGTSDETLPFFTQFLQFEASYDDLPTFQFFVIAMALVGGYLVLSLPISVVTILRPLATAPRLLLLVLDTGVLALNTAAASSAAAISYLAHSGNQNTNWLPICQQFGDFCQKSSGAVVSAFVSVVFFTILVVISGVALKRH
Protein: Protein GRISEA (MAC1 homolog) (Q92258)
Organism: Podospora anserina (Pleurage anserina)
Function: Copper-sensing transcription factor that regulates copper uptake by transactivation of Ctr3, a high affinity copper permease. Binds to the palindromic UAS sequence 5'-TGTTGCTCANNNNAGAGCAACT-3'. Also transactivates Sod2, a mitochondrial manganese superoxide dismutase through the palindromic UAS sequence 5'-GTTTGCTCA-3' with 352 bp separating the two inverted repeats. Loss of function indirectly leads to rearrangement of mitochondrial DNA associated with senescence in wild-type strains.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MPIINGQKMACGPCIRGHRSTKCNHYNERVMVPVRKPGRPLSTCPCPPGKPCVCGGVRVAIPKKQKCHCPAGTVDSATSSEFDPSPVDTPISPASRTSSNRVTKSGSGSKSASRRQSLALANLERMDPNSINLIPSPNGNGMIGITAMVSPRDATFGHPMGMVPMGPRESFVPAPPPDFGGPMGYNMPPSMPPHMPPPHYPPHIQIPQHIKTENGGFVPMLNGTFVSPVPIPAFVDGPHPQGMQAFNGPPPPPPSNPVLEPSAMSKPKGGSGGGGCCGGGKKAPQIQAPPPVPAPLPTPPQQQMPNIMPPPQPQNAPSGGGGSCCSSKSSQPPPMPQMSPNAMQAPPQPGFGQGFMPQYQTPIDIKMENMHHHQPFQFPGQTVFTYPAEYGSWQMPINPAIWQQVVSRPPTQQQHETPISATAPNGNNGTVGGNSHECGCGEGCQCVGCLAHPFNSQMLQYVQNAYSPNSSHGNSGSADSSANASPSANPLNLASPVEIPSGPELPPSHQTQPQPPPRPNANESDGSSNAPTPPNEGSPALSNEEELTALDYYFVHLPISALCGGALDMCPCDESCECVGCLVHNTAGFPQGDGGFS
Protein: Carbonic anhydrase (EC 4.2.1.1) (Q8IHW5)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- 60S ribosomal protein L5, putative
- Ribosome production factor 2 homolog
- 60S ribosomal protein L11a, putative
- Ribosome biogenesis regulatory protein
- Ribosome assembly protein RRB1, putative
- BRIX domain, putative
- mRNA-binding protein PUF3
- Periodic tryptophan protein 2, putative
- Phosphoenolpyruvate carboxylase
Sequence:
MKLLYLLYPILLFYNVNVFINYKKSRLMLEMIDKYNTHFVQTTKPYYEFNVTNLTNSKKKKKKKKRENHLIGSGENMQKKDEKNIKDFHINDYEIDGKTIHNKENKDSFKMNKNKLNDNEELFYMDNILSYKPNKKKLFTYSFSENEGNSEKEETLYNFKNMKNINSVQNNINKTFLYNKLKNVDYYEHGYNWDIGQCKTGKYQSPVDLPMKDLKERELKNISDVYLNLFDDDNYAWNNYNKPWMKGDFFYYYEYFIKKIVINRQNNIFQIKAARDGIIPFGVLFTTEQPAMFYADQIHFHAPSEHTFQGSGNRREIEMQIFHSTNYFYDIQDDKSKYKKKYGLHIYNNLKKNSKETSKKDSSRYHSYLMSFLMNSLSNEQLQNKYNKKKRIKKMKNQYEVISITFTSAEINASTINAFKKLPSEKFLRTIINVSSAVHVGSDPTLVELKDALNLDALMMMLNIEDMQFLSYQGSSTLPLCDENVSWKVAKQPLPVSTETILNFYYLLKKHTPNYSGSDNDNYRSLQNVEDNTRHYRKFSLVQVFPIQVLISSAISNIEDKKVINIIKDISPKNMSFTYYSKWDIYFILFIFYNIVLFLF
Protein: Anion exchange protein (A0A494BAK5)
Organism: Mus musculus (Mouse)
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Membrane {ECO:0000256|RuleBase:RU362035}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362035}.
Interaction partners:
Sequence:
SGESLSPELRGQLQALLLQRPQHHIQTMGIRPCRESNAFRKASRDEDAPLKHQNPLRQKLPAGAEAAAVLAGELGFLEQPLGAFVRLRNPIVLEPLTEMILPSRFFCLLLGPPTLGRSYHEMGRAAAVLLSDPQFQWSVRRASHLPDLLAALDAFLQEVTALPPGRWDRTARIPPPKYLPSQHKRFPSKLQEVTSLSRQSAALAEDKHHHGPHTPIPELQRTGRLFGGLIQDVRRKACWYTSDFLDALHPQCFSAVFYIYLATVTNAITFGGLLGDATEGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVTAFCLALVATEASLLVRYFTRFTEEGFCALISLIFIYDAMGKMLNLIRAYPIQRPGSSAYGCFCQYPGTGGNTSEWTSAKLKDTEDILSVPGLVNASFLPPPECIRQGGHPLGPSCHTVPDIAFFSLLLFFTSFLCAIALKHIKNSRFFPSVVRKVLGDFSSVLAILLGCGLDTFLGLATPKLLVPTEFKPTLSGRGWLVSPFGANPWWLSVAAALPALLLSILIFMDQQITAVILNRAEYRLQGAGFHLDLFCVAVLMLFTSALGLPWYVSATVISLAHIDSLRRESKACIPGEAPNFLGIREQRLTGLVVFVLTGVSIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFVKRVQLLLMPRKHQPDMLLLRHVPLSRVHLFTAIQLACLGLLWVVKSTPAAIVFPLMLLGLVAIRKALEWVFSPQELLWLDELMPEEEETIPENRSEPEHLFSGNDSEDSELMYQPKAPEINISVN
Protein: Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta (D3Z091)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPALDFYSKPAGRRTDLKLLRGLSGSDPTLNYNSISPPEGLPNSTSQDPQPGPDPWPKGSLSGDYLYIFDGSEGRCSLSPGSGDTDGSCKKLSPPPLPPRVSIWDAPPLPPRKGSPSPSKISQPNDINSFSSAEQPPDKLLVAQDPEEGELPDGRGQGHTLGSVDYDGINDAITRLNLKSTYDSEISSDATRGWKEGRGPLDFNKDTSGKPVARSKTMPPQVPPRTYTSRYANRKNATPGNNRRISAAP
Protein: ATP-dependent Clp protease regulatory subunit ClpC (EC 3.4.21.92) (Q8IM28)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Endoplasmic reticulum chaperone GRP170
- Heat shock protein 70
- ATP-dependent Clp protease proteolytic subunit
- ATP-dependent Clp protease proteolytic subunit
- Heptatricopeptide repeat-containing protein
- Heat shock 70 kDa protein
- Heat shock 70 kDa protein
- Heat shock protein 110
- GrpE protein homolog
- Endoplasmic reticulum chaperone BIP
Sequence:
MNVLYIFIAVLILNGILNIHVSKKKTSFLNNTYPINKYKTINIKRHYRKVQNRNNKLYVSLFDEYDEKCIKALIMAREVAKNDNENEILLKHLLIAIIRIDSNLVQNILKNFNISLTNFLDKFHVAINKISKSYTNSNNGHNNIYEQSGSAQNNLNEQEKKNISLTNEEIDMKNILNEEDENQVENRKQNENGNVNGNGNVNENVNENINENEKLLNDFINKHLKDMEEKINILKNLNNEEDNASLDDINNKDYIINDISSSNNITKENNNNNNNNNNNNDKGNFNNLDTNNDSGNLSNNVPKNESHNVLHNHTYKINNNNKMMNQEILGNPNFDIKFSENCKLVLHNAVLEAKRKRKIFVNIIDILLSIINIAQEKKHYDFLKYIEELNININDLKSLLLSYDEKNYDGNNIYDTNANNTNYNTHNRNIPLNNNNNNNNVSNKGYNNQRLNNMNNNEQANHIINSLNNEYLNNGRDYKYNEDHPFSSNNKFLNPSTSSASSISFMKDCLIDMVHEAQEKGDDHFFGRKKEIKRIIEILGRKKKSNPLLIGESGVGKTAIIEYLSYLILKDNVPYHLKNCRIFQLNLGNIVAGTKYRGEFEEKMKHLLSNMNKKKKNILFIDEIHVIVGAGSGEGSLDASNLLKPFLSSDNLQCIGTTTFQEYSKFIENDKALRRRFNCVTINPFTSKETYKLLKKIKYNYEKYHNIYYTDDSLKSIVSLTEDYLPTANFPDKAIDILDEAGVYQKIKYEKFMKQKLRAERLRKIRIHMNTQENNNNNNNNNNNISNNNNDYIISDEDQHIHNNNYGYNNYDVINQQKEFSNDEDINKLNDDDTNLRKTYKQEIDNKIKNDENGNNNIKTDTNGNILINNVESLQNDTYDETRNLIENVHMKYVTSDVIENIVSKKSSITYIKKNKKEEEKILKLKEKLNKIIIGQEKVIDILSKYLFKAITNIKDPNKPIGTLLLCGSSGVGKTLCAQVISKYLFNEDNLIVINMSEYIDKHSVSKLFGSYPGYVGYKEGGELTESVKKKPFSIILFDEIEKAHSEVLHVLLQILDNGLLTDSKGNKVSFKNTFIFMTTNVGSDIITDYFKLYNNNYSNLGFKYYIKKKKNENDINQSKQEEQYLVHTSNGNIENEQNKKYMDPTKQSNENNYESTINHTHTADTKYNNITTDNNNNNNNNNNNNNDHFEIFEEKLRTNKWYDELKPDIEEELKKKFLPEFLNRIDEKIIFRQFLKRDIINILQNMIDDLKKRIKKRKNINLIIDKNVINYICSDENNIYDMNFGARSIRRALYKYIEDPIAAFLISNIHEPNDSIYVQLTNDKKIKVQLIKAPVQQFSS
Protein: Ubiquitin carboxyl-terminal hydrolase MINDY-3 (EC 3.4.19.12) (Dermal papilla-derived protein 5) (Deubiquitinating enzyme MINDY-3) (Protein CARP) (Q9H8M7)
Organism: Homo sapiens (Human)
Function: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
Subcellular location: Nucleus {ECO:0000269|PubMed:12054670}.
Interaction partners:
- Transmembrane protein 45A
- Caspase recruitment domain-containing protein 6
- Growth hormone-inducible transmembrane protein
- Proton-transporting V-type ATPase complex assembly regulator TMEM9
- COP9 signalosome complex subunit 7a
- Death domain-containing protein CRADD
- Caspase recruitment domain-containing protein 8
- Caspase-1
Sequence:
MSELTKELMELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCSEEEQKELLCHTLCDILESACCDHSGSYCLVSWLRGKTTEETASISGSPAESSCQVEHSSALAVEELGFERFHALIQKRSFRSLPELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNEIEDASEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMKLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIPDSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN
Protein: Vicilin-like seed storage protein At2g28490 (Globulin At2g28490) (Q9SK09)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Seed storage protein.
Interaction partners:
- Late embryogenesis abundant protein M17
- 2S seed storage protein 5
- Oleosin 18.5 kDa
- Peroxygenase 1
- At5g22520
- Transmembrane protein
- DUF674 family protein
Sequence:
MEKNKRAIGFLLLVVLINGVMMTRSNGYEGEEEWGGAGGGEWGGAEGGGAWGGGGGGGGAWGGEGEGGGEWGGGGEGGGGGRRGWFMMRESRQVIKSEGGEMRVVLSPRGRIIEKPMHIGFLTMEPKTLFVPQYLDSSLLIFIRQGEATLGVICKDEFGERKLKAGDIYWIPAGSVFYLHNTGLGQRLHVICSIDPTQSLGFETFQPFYIGGGPSSVLAGFDPHTLTSAFNVSLPELQQMMMSQFRGPIVYVTEGPQPQPQSTVWTQFLGLRGEEKHKQLKKLLETKQGSPQDQQYSSGWSWRNIVRSILDLTEEKNKGSGSSECEDSYNIYDKKDKPSFDNKYGWSIALDYDDYKPLKHSGIGVYLVNLTAGAMMAPHMNPTATEYGIVLAGSGEIQVVFPNGTSAMNTRVSVGDVFWIPRYFAFCQIASRTGPFEFVGFTTSAHKNRPQFLVGSNSLLRTLNLTSLSIAFGVDEETMRRFIEAQREAVILPTPAAAPPHVGEMVSDRFV
Protein: Uncharacterized protein (Q38D33)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWKQRRNDQQFIRPMALGIITVLFVLCLWFGYHHGSCAAESRSTQAEAARRLLRKKELKECSDDCNELTEKVLRLNTEIGAVLAESAKFEEEIKKVTERGTGADNDRESCPVFQGAAEHTGGSSTTSGAGPRSEKPIPASVPSSRDSKERVSPLKKALDSSRQMYKRVCGRTPGCTILSDESLLQHRGGLRG
Protein: Coiled-coil domain containing 124 (M0R2F5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPKKFQGENTKSAAARARRAEAKAAADAKKQKELEDAYWKDDDKHVMRKEQRKEEKEKRRLDQLERKKETQRLLEEEDSKLKGGKAPRVATSSKVTRAQIEDTLRRDHQLREAPDTAEKAKSHLEVPLEENVNRRV
Protein: 26S proteasome regulatory subunit RPN8 (Q08723)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase RPN11
- 26S proteasome regulatory subunit RPN10
- 26S proteasome regulatory subunit RPN1
- 26S proteasome regulatory subunit RPN6
- Proteasome subunit beta type-4
- 26S proteasome regulatory subunit RPN3
- Proteasome subunit beta type-3
- Proteasome subunit alpha type-6
- Proteasome subunit beta type-7
- Proteasome subunit alpha type-2
Sequence:
MSLQHEKVTIAPLVLLSALDHYERTQTKENKRCVGVILGDANSSTIRVTNSFALPFEEDEKNSDVWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPKLRASDLKINELFKKYTQNNPLLLIVDVKQQGVGLPTDAYVAIEQVKDDGTSTEKTFLHLPCTIEAEEAEEIGVEHLLRDVRDQAAGGLSIRLTNQLKSLKGLQSKLKDVVEYLDKVINKELPINHTILGKLQDVFNLLPNLGTPDDDEIDVENHDRINISNNLQKALTVKTNDELMVIYISNLVRSIIAFDDLIENKIQNKKIQEQRVKDKQSKVSDDSESESGDKEATAPLIQRKNKKN
Protein: Diptericin (Q9TWW2)
Organism: Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
Function: Acute phase protein with antibacterial activity against the Gram-negative bacteria E.coli (MIC=6.25 ug/ml) and S.sonnei (MIC=12.5 ug/ml). Lacks antibacterial activity against the Gram-negative bacteria P.vulgaris, P.rettgeri and P.aeruginosa, and against the Gram-positive bacteria B.subtilis, S.aureus, M.luteus, B.megaterium, C.bovis and E.cloacae.
Subcellular location: Secreted {ECO:0000269|PubMed:1445217}.
Interaction partners:
Sequence:
DLHIPPPDNKINWPQLSGGGGGSPKTGYDININAQQK
Protein: Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) (D4A9G4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Melanosome membrane {ECO:0000256|ARBA:ARBA00004573}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004573}.
Interaction partners:
- Tyrosine 3-monooxygenase
- Aromatic-L-amino-acid decarboxylase
- Melan-A
- Amine oxidase
- Thyroid peroxidase
- Aspartate aminotransferase, mitochondrial
- Amine oxidase.
- Aspartate aminotransferase, cytoplasmic
- Amine oxidase
- Tyrosine aminotransferase
Sequence:
MFLAVLYYLLWSFQTSAGHFPRDCASSKNLMAKECCPPWMGDGSPCGHLSGRGSCQDILLSNAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRLLIRRNIFDLSASEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFKDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEMQELTGDENFTIPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWEIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADSSQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLGAALVGAVVATALAGLSSRLCHQKKKQPQEERQPLLMDKDDYHSLLYQSHL
Protein: Pyrroline-5-carboxylate reductase (P5C reductase) (P5CR) (EC 1.5.1.2) (P32263)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline, the final step in proline biosynthesis.
Interaction partners:
- Gamma-glutamyl phosphate reductase
- Glutamate 5-kinase
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
- Proline dehydrogenase, mitochondrial
- Prephenate dehydrogenase [NADP
- Threonine synthase
- Ornithine aminotransferase
- Phosphoserine phosphatase
- DNA-directed RNA polymerase II subunit RPB1
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
Sequence:
MTYTLAILGCGVMGQALLSAIYNAPKAADETAAAFYPSKIITCNHDEPSAQQVTDLVETFDESPNGIKVESTYGHNVSAVEEASVVLLGTKPFLAEEVLNGVKSVIGGKLLISLAAGWTIDQLSQYTSTVCRVMTNTPAKYGYGCAVVSYSADVSKEQKPLVNELISQVGKYVELPEKNMDAATALVGSGPAFVLLMLESLMESGLKLGIPLQESKECAMKVLEGTVKMVEKSGAHPSVLKHQVCTPGGTTIAGLCVMEEKGVKSGIINGVEEAARVASQLGQKKK
Protein: Protein RRP6-like 2 (AtRRP6L2) (A9LLI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as an important epigenetic regulator through multiple silencing mechanisms. Involved in association with RRP6L1 in the silencing of the solo LTR locus. Controls levels of non-coding RNAs (ncRNAs) from the solo LTR locus. Seems to function independently of the RNA-mediated gene silencing (RdDM) pathway. Functions redundantly with RRP6L1 in the regulation of FLC locus. Participates in the maintenance of trimethylated 'Lys-27' (H3K27me3) at FLC locus via the regulation of antisense long non-coding RNAs (lncRNAs) and the regulation of diverse antisense RNAs derived from the FLC locus. Seems not involved in the exosomal RNA degradation. May be involved in poly(A)-mediated RNA degradation.
Subcellular location: Nucleus {ECO:0000269|PubMed:18285452}. Nucleus, nucleolus {ECO:0000269|PubMed:18285452}. Cytoplasm {ECO:0000269|PubMed:18285452}. Note=Localizes predominantly in the nucleus. {ECO:0000269|PubMed:18285452}.
Interaction partners:
- Exosome complex component RRP4 homolog
- Exosome complex component RRP41 homolog
- Exosome complex exonuclease RRP46 homolog
- DExH-box ATP-dependent RNA helicase DExH9
- Exosome complex component RRP45B
- Ribosomal RNA-processing protein 43
- DExH-box ATP-dependent RNA helicase DExH10
- Exosome complex component RRP45A
- Nuclear nucleic acid-binding protein C1D
- Exosome complex exonuclease RRP44 homolog A
Sequence:
MSDGNMDVDESPVSWKVKSLEKLIDGSSFSSTLSRLSSSSRLIPTSRDFHFYYNFDEFKRPIDEITGTSQSTLATIGDSEQVWGKSMKFPGDVDDVYAEDWLCNVNDELIERFDVSVDEFQRIRKKEKEIGRSVVADDGDDGFQMVYGKKKKPVGNVVTGSAAVNGGGSVIDVKMAERDKNSSGKAKVPFHVPTIKKPQEEYNILVNNANLPFEHVWLERSEDDLRAMHPLEKFSVLDFVDKDVNEMEPVKPLPLEQTPFKFVQEVKDLKELVAKLRSVEEFAVDLEHNQYRSFQGLTCLMQISTRTEDYIVDTFKLRIHIGPYLREIFKDPKKKKVMHGADRDIIWLQRDFGIYVCNLFDTGQASRVLNLERNSLEFLLQHFCGVTANKEYQNADWRIRPLPEEMTRYAREDTHYLLYIYDLIKLELQRMAKDDAHTDSPLLEVYKRSYDVCTQLYEKELLTENSYLHVYGLQAAGFNAAQLAIVAGLCEWRDFIARAEDESTGYVLPNKVLLEIAKEMPDSVGKLRRMLKSKHPYIERNVDSVVSVIRQSMQHYAAFESAALSLKDVSPGNVMDKNIEPISEKKDLHTGDVASPSLKENSSQLESTRDLIMGAANTNEGRGLGSGLFGSAKVSAAVRISKKPSSGLGALLGNAASKKKSRTDEKVKEDVKLEQIRSSVNLSFHSFTEKVPDSKSTSETSPKVYGKPEEMSSTMPASVSKEDGVKELKDDSEEASEIVGTSGRVSESKVSSSEMGDIILLENGDEKKVDAEDEPMSLSELSTNFQKCFKSMNKSKKAQKQTEFLNIEPFDYEAARKEVKFGEGHKGRQGKREAAAGQKKGSTQEQSEFGQGKRRQAFPASGNRSMSFKN
Protein: rRNA 2'-O-methyltransferase fibrillarin 2 (AtFib2) (EC 2.1.1.-) (Fibrillarin-like protein 2) (Histone-glutamine methyltransferase) (Q94AH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins (Probable). Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (Probable). Site specificity is provided by a guide RNA that base pairs with the substrate (Probable). Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (Probable). Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity). Acts as negative regulator of expression of immune responsive genes, including pathogenesis-related gene 1 (PR1), and of resistance against bacterial pathogen. Binds to MED19A, a positive regulator of PR1 expression, to repress the activator activity of MED19A. In response to the bacterial pathogen-associated molecular pattern (PAMP) elf18, associates with the long non-coding RNA (lncRNA) ELENA1 (At4g16355), and releases its repression of MED19A. Possesses ribonuclease activity toward rRNA in vitro. Binds phosphoinositides, phospholipids and phosphatidic acid in vitro.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:18322146}. Note=Localizes to the fibrillar region of the nucleolus. {ECO:0000305}.
Interaction partners:
- Nucleolar protein 56
- Periodic tryptophan protein 2
- rRNA biogenesis protein RRP5
- Nucleolar protein 56
- Nucleolar protein
- H/ACA ribonucleoprotein complex subunit 2-like protein
- Bystin
- M phase phosphoprotein 10
- Probable nucleolar protein 5-2
- Uncharacterized protein At3g06530
Sequence:
MRPPLTGSGGGFSGGRGRGGYSGGRGDGGFSGGRGGGGRGGGRGFSDRGGRGRGRGPPRGGARGGRGPAGRGGMKGGSKVIVEPHRHAGVFIAKGKEDALVTKNLVPGEAVYNEKRISVQNEDGTKTEYRVWNPFRSKLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKSGGHFVISIKANCIDSTVPAEAVFQTEVKKLQQEQFKPAEQVTLEPFERDHACVVGGYRMPKKPKAATAA
Protein: AT3g54400/T12E18_90 (Eukaryotic aspartyl protease family protein) (Nucleoid DNA-binding-like protein) (Q9M2U7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable cysteine protease RD21B
- Defensin-like protein 159
- Defensin-like protein 112
- Subtilisin-like protease SBT4.15
- Defensin-like protein 286
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH11
- Defensin-like protein 151
- Serine carboxypeptidase-like 26
- Serine carboxypeptidase-like 34
- Serine carboxypeptidase-like 42
Sequence:
MRSHLLILLISLLILKSESINCNEKSHSSDLRVFHINSLCSPFKTSVSWADTLLQDKARFLYLSSLAGVRKSSVPIASGRAIVQSPTYIVRANIGTPAQPMLVALDTSNDAAWIPCSGCVGCSSSVLFDPSKSSSSRTLQCEAPQCKQAPNPSCTVSKSCGFNMTYGGSTIEAYLTQDTLTLASDVIPNYTFGCINKASGTSLPAQGLMGLGRGPLSLISQSQNLYQSTFSYCLPNSKSSNFSGSLRLGPKNQPIRIKTTPLLKNPRRSSLYYVNLVGIRVGNKIVDIPTSALAFDPATGAGTIFDSGTVYTRLVEPAYVAVRNEFRRRVKNANATSLGGFDTCYSGSVVFPSVTFMFAGMNVTLPPDNLLIHSSAGNLSCLAMAAAPVNVNSVLNVIASMQQQNHRVLIDVPNSRLGISRETCT