wanglab/gogpt-training-data huggingface dataset:
Protein: C2 domain-containing protein (Q8MPZ6)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MLSGERFESLLKSPKHHAKQFQEKVLNAYNYAIQLYTDAIESETFATYGQLILPLAVLVSVVLTILLCSVIWKILYYTSFLQVLGWLFGEMLWVILSWGLVAVLCYFALNHLGSTGEAAHTSSTFGSSVSGNGVANGGTHTSSGEWSNEIVSWLYSNFHKVPAPMDAWIKSLNEAAKKVTSPTKCEVLFEGFGDHSDVLQPPKISNVRVEHGPRDHLTVRSNVHLPCVKLRLVSSQRTPERMIVSNYDVSIVDLRGEVECRMACIANQLYLMGCFSGRPEMDIELRNTDPNAQYQVSIPMVEESIRRCLLSAVTNINLSEEMPEERNTFADTFSRTIYNPPTHSPSGTMRNSYNNYDTNLHVDAYGTQSSHRSNSPSGDVPEMFKKLNESHLISPSYNTNSIPNKMRIKVIKASRLGREVSQPFVNVEMDEPAQKYSTTKGINANPFWEETFDFDLTPATEEILFEIYEGNDKLHMNDDEGFLGLAIVNFEEIRRSGETVHSLKLQGRPYRKDAISGEITVQFDFFYDPNLLTSGKLTDTVKVTNPNGSEFRETLTTHRRPIYDPHDNFDGHEPIVPSKTTTVTVKTVSQTLKEKPTIQSVHGSLENAVDPATQKILDRQFKNHNDPKTRELEAKLQSVAQSMSASSTLDRPSKNGNNGQYYRDQTAPPEFHEELDVRQSRDKSKKAPTEKRDRSFFGELKDRLSGRRGRSQKRSKSVDVENNQLLEEAVSLPPSRDPSRTRYAVSSNDKYRETHSVGGRSGESTKSLYQHSTLILELDQDKQAKYFLIPPAMLNEPAASRLMRKGKKLHIYNDHTFVAVKVKGGATCNVCQQRIRSSFSKQAYQCRDCKMVCHKTCHYKTDAFCTQSNVSKLQIAKDVDWAHFLSHYQLEEFISSEGL
Protein: Toll-like receptor 9 (A8SZH4)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00046288}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00046288}. Endosome {ECO:0000256|ARBA:ARBA00004177}.
Interaction partners:
Sequence:
MQGYGVLLCLCLLTPAVRTTNPKFFPCDSNADSSVVNCSRRALTRIPVICSASVLSLDLSYTGIQQVGKDAFSGVPNLQKLSMTRNCLPSHMRALGSPSCHVEIHKDAFMCLKNLSTLLLEGNSLTSPLPRLPDSLEVLNLESNHLYNITQPLGTPNLKQLLLTMNCYYGNPCNQSFHIDEAVFRELTQLQYLTLGFNNVTSIPPGMPPSLKRLDLNENKISVLNEWAFANLTQLCQLNLGWNCQRCDHAAQPCFPCFNNTPLDINPRAFYAQNNSLKFLSLRGNSLRNIPEGLFSPLVHLERLDLSDNLLAIAIRTGTFFIELKRLTWISLIYNYEPMKTFKELVLSPNLTQMSGLKTLLLSGNFFHMVSEETVAVLAKFRWLEVLELRMNFIRSCNLSALAQLPALVRVGLSQNMLEFFPSFSTQSNMCKSFKSFQNQNRYDTVELQNPPMLLSDRKAVPDEPWHHPGPVVTAAEPGPNTLAILEDECTQNPTIFSFKNNLCNGAMSFDLSQNNILALNGSLFLGMEKAVCLDLSYNYMSQSLNGKQFLHLDNLAYLSMAHNRIDLYYGDAFKELNATLKALDLSNNEFHFLMRGMGHRFEFIKNLPNLEVLSLSDNSIGMRIDHTLYSDSLRYLYFSGNNLDIMWDTRSNDYITFFQNLTNLIYLDISRNQLRSLSPAAFCNLPVSLQVLRVSDNKLNYFPWENITALGRLCHLNLSLNYLSELPDKVIHFQAKLTLLDLSHNQISFLPEDFFSQALALRFLYLNHNKLKLLDRQSLPAPLRYGSALQLLTLHANPFDCSCDTSWFADFLRASQVEILLLTTAVHCGFPESQQGASVLSMDPRSCQEIYGSLTFLSMTFLTLVFTALPLLRHLYGWDVWYCFQVLWAGHKGYSQLPGGNFQSQYDAFVVFDTGNHAVRDWVYNELLIHLENVGRRRFCLCLEERDWVPGLSCIENLHSAVYSSMKTVFVLTSGASGGGARVSRVDGVTRQAFYMVQQRLLDEKVDVAVLVLLDEVFPKLKYLQLRKRLCRKSVLSWPRNPQAQPLFWNNMKTALASDNIRSYDSNVSESFI
Protein: protein disulfide-isomerase (EC 5.3.4.1) (Q57WS0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTPFSCRKTSLLKAICIFAYFASAAHANEPDAALEGVVDLTSNNFDSSVGKDVAALVEFYAPWCGHCKNLVPEFAKLGRAAAGAKDKVLIAKVDATAQKDLATRFEVNGYPTILFFPAGSQKPEKYSEGREAKAFVSYLNNQIKGLNLFLPREHKYVMALDQSNFDKVALDEGKDAFVLFYAPWCGHCKRLHPSFESLAKVYQNEKDLIIANVDADDKSNSEVTKRYKVEGYPTLVFFPKGNKGNPVNYEEGRTLDDMIKFVNERTGKKRTSSGDFDKTVGVDETVTNLMKEMAQSSKNKEERERLLAQIQQAVSPKALGEGAMHYIRIATNVLENGHEYISKEHERVGRLLKGSLTGPKRDSLTIRFNILSAIKGE
Protein: Uncharacterized protein YibI (P32108)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Inner membrane protein YibH
- Hydroxycarboxylate dehydrogenase A
- Uncharacterized protein YecJ
Sequence:
MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAIHTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRLEHQLAAEKKTDYSTFPEI
Protein: At1g53120 (RNA-binding S4 domain-containing protein) (Q93YQ0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Class I peptide chain release factor
- 50S ribosomal protein L33
Sequence:
MAVTSLAPPWVILRLAFRSVAASSCLHTNQKTLITNLSIPTSFPLRQSALRRCYSAEAIKGDVDFLLKGVGDQAVAKEVKQILEMARRASSKREVLHTDFLTPPIVKESVSLLEKFADVKIVAQGGYPEAERCRISIGHPDVLTSDPDIVAALSITGNFGFQPCSHGDFLGAILGTGISREKLGDILIQEEKGAQVLIVPELVDFVVTALDKVGNVGVTCSKIPLLALEYEPPRTNSFKTVEASLRIDAVASAGFKISRSKLVDLISSKDVRVNWATVTKNGTIVKTGDVVSVSGKGRLKIGEINETKKGKFAVEIIRYL
Protein: Paired box 6 (A0A1W2PPJ2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYW
Protein: Metacaspase-1 (EC 3.4.22.-) (O74477)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in cell death (apoptosis).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Bax inhibitor 1
- Calnexin homolog
- Sensor for unfolded proteins in the ER ire1
- Protein kinase C-like 1
Sequence:
MSYNSNPYNGGQYPPYNTYTRPNYSPNNGSQSNNTVHQYQPPRMPPPSTRPQTDGNSNQIPMENVGHISLSSANSHAYAPPSGPPPNTGANSYGNPNYSGPQLPNTQTQSYNLAGGGNFQYQYSTCQGKRKALLIGINYLNTQNELQGCINDVMSMSQLLIQRYGYKQEDMVIMTDTASNQRAIPTRQNMLDAMRWLVSDAQPNDALFFHYSGHGGQTKDLDGDEVDGYDETIYPLDHQYAGQIIDDEMHEIMVKPLPAGCRLTALFDSCHSGGALDLPFTYSTKGVLKEPNMLKESGMDVLHAGLSYASGDIMGAINNVKNIFTSATNGFNNNALQYSRQVKFSPADVISLSGCKDNQTSADTSVNGFATGALSYAFREVVTQNPQLSYLQLLRGIRQVLSNKYSQLPQLSCSHPLDMNLAMVL
Protein: Connector of kinase to AP-1, isoform G (M9PF42)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGTNSGATAGINNKPVGGATGAGVLVGGGVGGANSSIGGVLSNSLGGGGSGGLSISGLNAGGQNANVGGMGNVGGDDGGNGMVGGGVNNQQATTPQYTIPGILHFIQHEWSRFELERSQWDVDRAELQARIAMLLGERKCLESLKSDLTRRIKMLEYALRQERAKFYRLKYGTDPPQLNEFKPSNEDAGLAGEVATDSEVPYSSVSNTTWRQGRQMLRQYLAEIGYTDNIIDVRSNRVRSILGLNNNAEHDGSGGGLGGGLGGGTGGENLSPNINGNESNKRASETEVQQSIDEIIVDTEAAVMANFEFLGATEMSDDDEISDDLEMVATDNDDTDVKLAKRAKSGKDMLTEEVDGSLGLGELAQLTVNNESDGAYDANSKDGTGGSAGGAGYRKTWNAKYTLRSHFDGVRSLIFHPEEPVLITASEDHTLKLWNLQKTVQAKKSASLDVEPLYTFRAHTGPVLCLGMSSSGETCYSGGLDGNIECWQLPSPNIDPYDCYDPNVHSGTLEGHTDAVWGLTTMQSNIVSCSADGTVKLWSPYNKEPLLRTYTASEAEGVPSSVDFVRNEVDHIVVAYNSAHCIVYDTETGKQVVRLEAAQEMSGNTGKFINKVVSHPTLPITITAHEDRHIRFWDNTSGTLVHSMVAHLEPVTSLAVDAHGLYLLSGSHDCSIRLWNLDNKTCVQEITAHRKKFDESIFDVAFHATKPYIASAGADGLAKVFV
Protein: Protein OSCA1 (CSC1-like protein At4g04340) (Hyperosmolality-gated Ca2+ permeable channel 1.1) (AtOSCA1.1) (Protein reduced hyperosmolality-induced [Ca(2+)]i increase 1) (Q9XEA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a hyperosmolarity-gated non-selective cation channel that permeates Ca(2+) ions. Shows the following permeability sequence: K(+) > Ba(2+) = Ca(2+) > Na(+) = Mg(2+) = Cs(+). Mechanosensitive ion channel that converts mechanical stimuli into a flow of ions.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25162526}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein MID1-COMPLEMENTING ACTIVITY 1
- Mechanosensitive ion channel protein 10
- Protein MID1-COMPLEMENTING ACTIVITY 2
- Two pore calcium channel protein 1
- Mechanosensitive ion channel protein 8
- Putative cyclic nucleotide-gated ion channel 19
- Mechanosensitive ion channel protein 9
- Mechanosensitive ion channel protein 5
Sequence:
MATLKDIGVSAGINILTAFIFFIIFAFLRLQPFNDRVYFSKWYLRGLRSSPASGGGFAGRFVNLELRSYLKFLHWMPEALKMPERELIDHAGLDSVVYLRIYWLGLKIFAPIAMLAWAVLVPVNWTNNELELAKHFKNVTSSDIDKLTISNIPEGSNRFWAHIIMAYAFTIWTCYMLMKEYETVANMRLQFLASEGRRPDQFTVLVRNVPPDPDETVSELVEHFFLVNHPDNYLTHQVVCNANKLADLVSKKTKLQNWLDYYQLKYTRNNSQIRPITKLGCLGLCGQKVDAIEHYIAEVDKTSKEIAEERENVVNDQKSVMPASFVSFKTRWAAAVCAQTTQTRNPTEWLTEWAAEPRDIYWPNLAIPYVSLTVRRLVMNVAFFFLTFFFIIPIAFVQSLATIEGIEKVAPFLKVIIEKDFIKSLIQGLLAGIALKLFLIFLPAILMTMSKFEGFTSVSFLERRSASRYYIFNLVNVFLGSVIAGAAFEQLNSFLNQSPNQIPKTIGMAIPMKATFFITYIMVDGWAGVAGEILMLKPLIIYHLKNAFLVKTEKDREEAMNPGSIGFNTGEPQIQLYFLLGLVYAPVTPMLLPFILVFFALAYVVYRHQIINVYNQEYESAAAFWPDVHGRVITALIISQLLLMGLLGTKHAASAAPFLIALPVITIGFHRFCKGRFEPAFVRYPLQEAMMKDTLERAREPNLNLKGYLQDAYIHPVFKGGDNDDDGDMIGKLENEVIIVPTKRQSRRNTPAPSRISGESSPSLAVINGKEV
Protein: Tripartite motif-containing protein 66 (O15016)
Organism: Homo sapiens (Human)
Function: May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:25593309}. Note=Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm. {ECO:0000250|UniProtKB:Q924W6}.
Interaction partners:
- Chromobox protein homolog 3
- Histone H3.3
- Histone H3.3C
- Histone H3.1
- Histone H3.1t
- Histone H3.2
- Histone H3-7
- E3 ubiquitin-protein ligase TRIM17
- Gamma-butyrobetaine dioxygenase
Sequence:
MSFMGLPLAGQKHCPKSGQMEAMVMTCSLCHQDLPGMGSHLLSCQHLLRKDCFQGLIQELGQIAKAHETVADELISCPGCERVYLTRDVTEHFFLHCVPTEQPKMARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
Protein: Large ribosomal subunit protein uL4m (39S ribosomal protein L4, mitochondrial) (L4mt) (MRP-L4) (Q32PI6)
Organism: Bos taurus (Bovine)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11279069, ECO:0000269|PubMed:11551941, ECO:0000269|PubMed:16510155}.
Interaction partners:
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein bL21m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein uL14
- Ribosomal protein
- Small ribosomal subunit protein uS7m
- Large ribosomal subunit protein bL9m
- Large ribosomal subunit protein uL11m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL27m
Sequence:
MQQLVRAGARAWLRPRGCRGLSALTEEAVQSAEKPEPLANAGPQAPVLRRCELPVPLHRRPVQAWVESLRGYEQERVGLTELHPDVFSTAPRLDILHQVAIWQKNFKRISYAKTKTRAEVRGGGRKPWQQKGSGRARHGSIRSPIWRGGGVAHGPRGPTSYYYMLPMKVRVQGLKVALTVKLAQDDLHIVDSLELPTTDPQYLMELARYRRWGDSVLFVDLEHEDMPQNVVAATSGLKTFNLIPAIGLNVHSMLKHQTLVLTLPTVAFLEEKLLWHDSRYTPLYPFRLPYRDFP
Protein: Ras-related protein Rab-5B (PfRab5B) (EC 3.6.5.2) (Q76NM7)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Small GTPase which regulates vesicle trafficking between organelles (Probable). May be involved in the trafficking of the N-myristoylated AK2 from the endoplasmic reticulum to the parasitophorous vacuole membrane.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24498355}; Lipid-anchor {ECO:0000269|PubMed:24498355}; Cytoplasmic side {ECO:0000305}. Vacuole membrane {ECO:0000269|PubMed:24498355}; Lipid-anchor {ECO:0000269|PubMed:24498355}; Cytoplasmic side {ECO:0000305}. Vesicle {ECO:0000269|PubMed:24498355}. Note=May localize to the endoplasmic reticulum and to the parasitophorous vacuole membrane. {ECO:0000269|PubMed:27316546}.
Interaction partners:
- Vacuolar protein sorting-associated protein 9, putative
Sequence:
MGCSSSTERLTSTKNINIVTSPAQQQKKNAQDTKVKIVLLGDSGVGKSSIALYLCHGRFSEKHQVTIGAAFLHHNIELKNGATMKLHIWDTGGQERFRSMAPLYYRDAYGAVVVYDSNNVESFDSLKYWINEIKSNGPRNCCIMVVANKKDLPQKLNSEMVMKFCEQENVSFIECSAKTGENITTLFEKLASRIYSRFKEVLYYNNP
Protein: Ribosome biogenesis protein SSF2 (Q12153)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for biogenesis of the 60S ribosomal subunit.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:9611192}.
Interaction partners:
- Ribosomal RNA-processing protein 15
- Ribosome production factor 1
- rRNA-processing protein EBP2
- ATP-dependent RNA helicase DRS1
- Ribosome biogenesis protein ERB1
- Ribosome biogenesis protein NSA1
- Proteasome-interacting protein CIC1
- Ribosome biogenesis protein RPF2
- Ribosome biogenesis protein 15
- Ribosome biogenesis protein SSF1
Sequence:
MAKRRQKKRTHAQITPEQERDIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAVKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSDEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRIFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQTSLSQKTPVKMTDNEEREKGIEEEDVEMEEPKPSENSQPTPRKKAIKLTELGPRLTLKLVKIEDGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRRKEQEENIAKKKAVKDAKKQRKLERRKARAEEQGEGQGKDGAMSDDGSSSSEDEHYSDVPEDLDSDLFSEVE
Protein: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (EC 5.3.1.16) (5-proFAR isomerase) (Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase) (P40545)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the isomerization of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Imidazole glycerol phosphate synthase hisHF
- Histidine biosynthesis trifunctional protein
- Imidazoleglycerol-phosphate dehydratase
- ATP phosphoribosyltransferase
- Histidinol-phosphate aminotransferase
- Multifunctional tryptophan biosynthesis protein
- DNA repair protein RAD16
- Tryptophan synthase
- N-
- GMP synthase
Sequence:
MTKFIGCIDLHNGEVKQIVGGTLTSKKEDVPKTNFVSQHPSSYYAKLYKDRDVQGCHVIKLGPNNDDAAREALQESPQFLQVGGGINDTNCLEWLKWASKVIVTSWLFTKEGHFQLKRLERLTELCGKDRIVVDLSCRKTQDGRWIVAMNKWQTLTDLELNADTFRELRKYTNEFLIHAADVEGLCGGIDELLVSKLFEWTKDYDDLKIVYAGGAKSVDDLKLVDELSHGKVDLTFGSSLDIFGGNLVKFEDCCRWNEKQG
Protein: Transthyretin (O93330)
Organism: Sparus aurata (Gilthead sea bream)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU361269}.
Interaction partners:
Sequence:
MLQPLHCLLLASAVLCNTAPTPTDKHGGSDTRCPLMVKILDVKGTPAGSVALKVSQKTADGGWTQIATGVTDATGEIHNLITEQQFPAGVYRVEFDTKAYWTNQGSTPFHEVAEVVFDAHPEGHRHYTLALLLSPFSYTTTAVVSSVHE
Protein: Adipocyte plasma membrane-associated protein (Protein BSCv) (Q9HDC9)
Organism: Homo sapiens (Human)
Function: Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.
Subcellular location: Membrane {ECO:0000269|PubMed:18513186}; Single-pass type II membrane protein {ECO:0000269|PubMed:18513186}.
Interaction partners:
- Exosome complex component 10
- Large ribosomal subunit protein uL23
- Ferredoxin-fold anticodon-binding domain-containing protein 1
- Translation initiation factor IF-2, mitochondrial
- Eukaryotic translation initiation factor 5B
- U3 small nucleolar ribonucleoprotein protein IMP3
- Large ribosomal subunit protein bL20m
- Small ribosomal subunit protein uS4
- DNA-directed RNA polymerase II subunit RPB3
- Protein RRP5 homolog
Sequence:
MSEADGLRQRRPLRPQVVTDDDGQAPEAKDGSSFSGRVFRVTFLMLAVSLTVPLLGAMMLLESPIDPQPLSFKEPPLLLGVLHPNTKLRQAERLFENQLVGPESIAHIGDVMFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPVCGRPLGIRAGPNGTLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMSFVNDLTVTQDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVLVAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIRPSSSGGYWVGMSTIRPNPGFSMLDFLSERPWIKRMIFKLFSQETVMKFVPRYSLVLELSDSGAFRRSLHDPDGLVATYISEVHEHDGHLYLGSFRSPFLCRLSLQAV
Protein: Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma) (P28701)
Organism: Gallus gallus (Chicken)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- Peroxisome proliferator-activated receptor gamma
- Peroxisome proliferator-activated receptor alpha
- Nuclear receptor subfamily 1 group H member 3
- Retinoic acid receptor RXR
- Thyroid hormone receptor beta
- Nuclear receptor corepressor 2.
- Mediator of RNA polymerase II transcription subunit 1
- Thyroid hormone receptor alpha.
- Bile acid receptor
- Uncharacterized protein.
Sequence:
MYGNYPHFIKFPAGFGNSPVHASSTSVSPSSSLSVGSTVDGHHNYLEAPTNASRALPSPMNTIGSPVNALGSPYRVIASSIGSHPVALSSSAPGMNFVTHSPQPNVLNNVSSSEDIKPLPGLPGIGNMNYPSTSPGSLAKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQGSRERSENEAESTSGGSEDMPVERILEAELAVEPKTEAYSDVNTESSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSSPSEVESLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQVT
Protein: Bud site selection protein 6 (Actin-interacting protein 3) (P41697)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not essential for mitotic growth but is necessary for normal morphogenesis. Involved in the organization and/or function of the actin cytoskeleton.
Interaction partners:
- Protein SPA2
- Protein PEA2
- Protein BNI1
- Actin
- Uncharacterized protein YGL015C
- GTPase-activating protein GYP3
- GTPase-activating protein MSB4
- BNI1-related protein 1
- Profilin
- Protein BIM1
Sequence:
MKMAVDDPTYGTPKIKRTASSSSSIETTVTKLLMSTKHLLQVLTQWSKGTTSGRLVSDAYVQLGNDFKVVSKFFMHAKVDMSDVGDVPMALRRVLEVTLREPPSDETLNKHLPKIREIIVTLLDKLKVKQAILKNMQQEHRISVKSHHQQNPSFTSNLSLGSEGTREGTPLSSRKSSIVRDQRQSDSVENSYGEKVNSTSTGTPSAQSAEATLTKPRTNIKQNLKSNNAPNASDDDDALSQLKKGTNLQRRASKRYSAYHMAKLTNQSTTEAAAAAGLMTTPSPSMLHLEETVRKSKLYGNNNNDDDRNINSAENKGKSIDDVSKASPLAKTPLPIENVRASPRRLSSVVTTSPDKAMNGTCPVFLRIGDKTKKCHVQLPTTKNALRLLFIERFAYSPGANSFPDIYIMDPQYGVFYELEELNLLDIKEGFVIELKLEENPNNTIKEFIDTVKMEISNSQNDIIRHLKEMSFGSAISGKQTEVLPQPGLEANKHDLVGQNKKDDDKTIKDIQYELGKIKQVHNINRSNINETIFNILRKVDNFKSLSFSAKNSSNRMYMEKSQTELGDLSDTLLSKVDDLQDVIEIMRKDVAERRSQPAKKKLETVSKDLENAQADVLKLQEFIDTEKPHWKKTWEAELDKVCEEQQFLTLQEELILDLKEDLGKALETFDLIKLCCEEQEKNPSRSKSNPILPIMRPGTFNQVREQVMVAVQSLNPDHDSRVEAIDKAEKMWEMERKLKASNEFDDELENFVGNSNLKKSGGFEEVERIRKQKDEANLRAYFGPGFT
Protein: F-box/kelch-repeat protein At3g23880 (Q9LIR8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein eS12z
- Molybdopterin synthase catalytic subunit
- FAD synthetase 1, chloroplastic
- Adenylosuccinate synthetase, chloroplastic
- Protein METHYLENE BLUE SENSITIVITY 1
- Ras-related protein RABH1b
- Nucleoporin-like protein
Sequence:
MDETTREMFSPHNLPLEMMEEILLRLPVKSLTRFKCVCSSWRSLISETLFALKHALILETSKATTSTKSPYGVITTSRYHLKSCCIHSLYNASTVYVSEHDGELLGRDYYQVVGTCHGLVCFHVDYDKSLYLWNPTIKLQQRLSSSDLETSDDECVVTYGFGYDESEDDYKVVALLQQRHQVKIETKIYSTRQKLWRSNTSFPSGVVVADKSRSGIYINGTLNWAATSSSSSWTIISYDMSRDEFKELPGPVCCGRGCFTMTLGDLRGCLSMVCYCKGANADVWVMKEFGEVYSWSKLLSIPGLTDFVRPLWISDGLVVLLEFRSGLALYNCSNGRFHYPVSNSISGCRDAKVYLKTMVSPNDL
Protein: Elongin-C (Q384S2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cullin 1, putative
- Ubiquitin, putative
- COP9 signalosome complex subunit 5
- RING-type domain-containing protein
- RING-type domain-containing protein
- PCI domain-containing protein
- COP9 signalosome complex subunit 4
- Spt4/RpoE2 zinc finger domain-containing protein
- COP9 signalosome complex subunit 3 N-terminal helical repeats domain-containing protein
- Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein
Sequence:
MSRANVPFNPMRRTPPPPPCIDTFTLVPSDYMSMLSADGHKFVLHRDCACASPLIRKALTNLVDPGVPEMRFDWANGDNEPPVIYFTKAPTALLEVVIKYLYYKHRYEGDTDYRPPFDVPRQIALDIMKLAQVLQC
Protein: Spermidine synthase (EC 2.5.1.16) (F1R3G8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- S-adenosylmethionine decarboxylase proenzyme
- ornithine decarboxylase
- Agmatine ureohydrolase
- Spermine synthase.
- S-methyl-5'-thioadenosine phosphorylase
- Peroxisomal N
- Diamine acetyltransferase 1
- Amine oxidase.
- Alpha-aminoadipic semialdehyde synthase, mitochondrial
- Diamine acetyltransferase 2b isoform 1
Sequence:
MDNIKDGWFTETCTLWPGQAMSLQVEEVLYHKKSKFQDVMVFKSKTYGNVLILDGVIQCTERDEFSYQEMIANLPLCCHPCPKKVLIIGGGDGGVLREVVKHPLVESVVQCEIDEDVINVSKKYLPGMAKGFFSPKLTLHVGDGFEFMKKNQDAFDIIITDSSDPVGPAESLFKESYYQLMKTALCEGGILCCQGECQWLHLELIKEMRTFCKTLFPVVDYAYCTIPTYPSGQIGFMLCSKNSKTNFREPLRELTRDEIESMSLKYYNPEIHRAAFILPEFARKVLSEA
Protein: Septin B (C8V1M3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Septin
- Septin-type G domain-containing protein
- Septin
- Septin
Sequence:
MASPPPSNGTPATASPPSSKPGSPFVERSNPMGAGNAQTVTSKDPKAAAQAATDMKNVVRRKLTGYVGFANLPNQWHRKSVRKGFNFNVMVVGESGLGKSTLVNTLFNTSLYPPKERAGPSHDIIPKTVSIQSISADIEENGVRLRLTVVDTPGFGDFVNNDDSWRPIVENIEQRYDAYLEAENKVNRTNIIDNRIHACVYFIQPTGHSLKPLDIEVMRRLHTKVNLIPVIAKADTLTDDEISMFKKRILADIQHHSIQIFEGPRYELDDEETIAENQEIMSKVPFAVVGANSEVATSDGRKVRGRSYPWGIIEVDNEEHCDFVKLRQMLIRTHMEELKEHTNNHLYENYRSDKLTQMGVAQDPSVFKEVNPAVKQEEERALHEQKLAKMEAEMKMVFQQKVAEKESKLKQSEDELYARHREMKEQLDRQRAELEEKKARLESGRPLEEKGKRKGFSLR
Protein: E3 ubiquitin-protein ligase MAG2 (EC 2.3.2.27) (Q06436)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Uncharacterized protein YKR073C
- Uncharacterized RING finger protein YBR062C
- Uncharacterized protein YMR075C-A
Sequence:
MVEPDMQKKASGGSGGSEMDTLNATSNSSKQGVSNNKRNPVSKKKPGNKVSDGRDNAHNYHGEGRRKSSKQQRSRTPYKETSTRINDQDIDLSIQEEILGGNFKLRGRKTQVSINHLLNFQLPEVEREKSRSSSSKKSNRRRDEHVHLHGDTFVNVNYRLLVDDRFDYPEQNCNPNVPVDQEKILRVIVPKGQNCSICLSEEPVAPRMVTCGHIFCLSCLLNFFSIEETVKNKETGYSKKKKYKECPLCGSIIGPKRVKPVLYEDDFDVTRLNQKPEPGATVHLQLMCKPHGSLLPLPVALHLDPLKCGNFPPANLGSIKHYAHIMKCGVSYSLELYQKDIVAIQEQYEIDKAIYNDSGKFVKQSIENINDQISTLLAATTDLSPLSNDINNGLDNFHFDDDLLTKYDDSSAYFFYQTLVASSTKYFLSPLDVKILLTIFHYYSKFPESIETTVENIHYDTVVTEQLIRRYKYIGHLPIGTEIALLDLDWRKIPFLPKEIYEQFAHELKQRRRKFTMKKQKEDKEKKLYEKRLEQEHAEFYRKENGNSLKFEDSVQMATHYESIVSSSIPLNSLGISMLGPPTNSCSTPQKQAPSHTKRTIWGTSIAVTEDEKASKENKEFQDMLLQRIRQEDSSDVTDSTDSPPTSNGKRGRKKKGKVMLFSSNHQALG
Protein: StAR related lipid transfer domain containing 10 (H0YGA9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
CRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGHEEDVQGVPQVPRVETEAPASLQAVA
Protein: Homeobox protein Nkx-6.1 (Homeobox protein NK-6 homolog A) (P78426)
Organism: Homo sapiens (Human)
Function: Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity). Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Neurogenin-3
- Insulin gene enhancer protein ISL-1
- Solute carrier family 2, facilitated glucose transporter member 2
- Pancreas/duodenum homeobox protein 1
- Hepatocyte nuclear factor 6
- Insulin
- Pro-glucagon
- Hepatocyte nuclear factor 3-beta
- Transcription factor MafB
- Neurogenic differentiation factor 1
Sequence:
MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHASEPESSS