wanglab/gogpt-training-data huggingface dataset:
Protein: P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999) (Q9H244)
Organism: Homo sapiens (Human)
Function: Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11196645, ECO:0000269|PubMed:12578987, ECO:0000269|PubMed:24670650, ECO:0000269|PubMed:24784220}; Multi-pass membrane protein {ECO:0000269|PubMed:11196645, ECO:0000269|PubMed:12578987, ECO:0000269|PubMed:24670650, ECO:0000269|PubMed:24784220}.
Interaction partners:
- P2X purinoceptor 1
- P2Y purinoceptor 1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Cytochrome P450 2C19
- Guanine nucleotide-binding protein G
- P2Y purinoceptor 13
- Triggering receptor expressed on myeloid cells 2
- Transmembrane protein 119
- Platelet glycoprotein VI
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
Protein: Snaclec mamushigin subunit beta (Q9YI92)
Organism: Gloydius blomhoffii (Mamushi) (Agkistrodon halys blomhoffi)
Function: Binds to platelet GPIbalpha (GP1BA) and enhances platelet aggregation at low-shear stress. At high-shear stress, blocks platelet aggregation in a dose-dependent manner.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MGRFIFLSFGLLVVFVSLSGTGADCPSDWSSYEGHCYRVFQKEMTWEDAEKFCTQQRKESHLVSFHSSEEVDFVVSMTWPILKYDFVWIGLNNIWNECMVEWTDGTRLSHNAWITESECIAAKTTDNQWLSRPCSRTYNVVCKFQE
Protein: Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2) (Q20065)
Organism: Caenorhabditis elegans
Function: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular location: Endoplasmic reticulum lumen.
Interaction partners:
- Prolyl 4-hydroxylase subunit alpha-1
- Protein disulfide-isomerase 2
- Proline dehydrogenase 1, mitochondrial
- Pyrroline-5-carboxylate reductase
- Multifunctional procollagen lysine hydroxylase and glycosyltransferase
- Putative pyrroline-5-carboxylate reductase 4
- Hypoxia-inducible factor prolyl hydroxylase
- Probable protein disulfide-isomerase A4
- Leprecan-like alpha-helical domain-containing protein
- Protein disulfide-isomerase
Sequence:
MRAVLLVCLLAGLAHADLFTAIADLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEYVHRNAHAESVGPEFVTNPINAYLLIKRLTTEWKKVENIMLNNKASTFLKNITDNRVRSEVKFPGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYHCLMWMQVALVKIENENPPTIEEWEILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDMLQGKDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEIEVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDLDPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPCGLEEEVQENFIGDLSPYANDP
Protein: Proton channel OtopLc (Otopetrin-Lc) (DmOtopLc) (B7Z0W9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q80VM9}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDSSPDLSLKLRRGSSDSRDNFYMDFAQGIDSDIEEVDNTANNQEAGEVPPPPLPTVSLAEEVLLLVAPPPPPPSLLGQPLPTLTETDDIPPTPTPPPQQKDDEGDDEDEREEPVPEQDQGAPAAPSPPGSPINSVLELELIPPPPLSPMDDAGLRTDDDGEGEETDDAEEVAAIPPPHEMLDIESNPDEEEEEEEQEQASQEDTPKEEDEEEDDDKSTPPPPLPPLPSNFSYVQGHNLGQVTPPLTKSPSNSPSPPVTPPPCPELNISRMVSPPAQHISQIPPLTPSDESEGEAESQPNSPPLRLDAEQPPPDMDQPEPEDQPPEPENEPEPEPEPEPEPEPVSGAREDYSRSLDNEDESTTITTPPSNGYSASSIIAPPPEHFAELDEDRGFIPPPPLEQEPEEEVEEEEEEEEEELTKETDEISVDRESLQDQGGDSISSPRPASILTGSISTSVGGGAGGSPKPESRGPSRSGSQRSQLRSGSQQGSIAESRGGSRIGSRTGSVASAQAAGVLSPQASLKSQTSIRSQGQAGVRSPAGSIKSGSQRMQSPQAGEGAPAMPSPPLMRSPPPELARQMHSPPRITTPPRVCSPPLVSSPPKLAESAAAAVGVAATVKEQIGSSSSTAEPLEPSKPEPLKPPIATVSYQDEQKPSPPPTAAAAPAVTTTAATTAVTSQPRSHFTSSHHHYHLPHQFQHPHHQNHHTHSVRVPTPTVPSSYAPPPPPDSGSSSSPVDRRRLFMAGVAPPIAAGAGSLMAMPAEPAVAISPGRVSARSGSQHHVTIDESSLPSHKGNIQETPGPSGLIIGGGDGDGDRDIGGGGGPDSSDPPSSPGGSSSQPALSGSQADGQLALMYHSHQLTNYPVLPAIKRTHRPSFVYPPMPRVKAGDALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRPKLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHYGSFYLRMGAVAFGIGSMIYSGLEFGQYFELNPDTKCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQETKHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPTAHLRVPRGLKGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMISSPMKRSPHHYSVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIRHLQYDAYRSFSLDDILLVGAQTGSFLYNIFTVIAGHFTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAESHPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLKPTYMXEFARSRIQSIAQQQQFCEDLKTNLSYCYCSTTLAGGELETVEEVDSGESNSAEDAGAGAGSGGSRGSGGGAGAAEAGEAGEEGQQGGDSSCGLKAPIRALSPQSLNTEKAFCPVYVINGE
Protein: Casein kinase 1-like protein 4 (EC 2.7.11.1) (Protein CASEIN KINASE I-LIKE 4) (CK1.4) (Q8LPI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Protein kinase involved in blue light responses (e.g. hypocotyl elongation and flowering) by phosphorylating CRY2 to reduce its stability.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16126836, ECO:0000269|PubMed:23897926}. Nucleus {ECO:0000269|PubMed:16126836, ECO:0000269|PubMed:23897926}. Note=Translocates mostly in nucleus upon blue light treatment, especially in nuclear bodies. {ECO:0000269|PubMed:23897926}.
Interaction partners:
- Cryptochrome-2
- At3g49990
- Serine/threonine-protein kinase MPS1
- Protein BIC2
- Cryptochrome-1
- Bystin
- Serine/threonine-protein kinase RIO2
Sequence:
MERIIGGKYKLGRKIGGGSFGEIFLATHIDTFEIVAVKIENSKTKHPQLLYEAKLYRTLEGGSGIPRIRWFGVDGTENALVMDLLGPSLEDLFVYCGRKFSPKTVLMLADQMLTRIEYVHSKGYLHRDIKPDNFLMGLGRKANQVYLIDFGLAKRYRDANTNRHIPYRENKNLTGTARYASCNTHLGIEQGRRDDLESLGYVLLYFLRGSLPWQGLKAVDKKQKYDKICEKKISTPIEVLCKSHPVEFASYFHYCHTLTFDQRPDYGFLKRLFRDLFSREGYEFDYIYDWTIIKYQQSQKTRSQSQAVPGSSNARAIPMDTSNHRGGTKISHEAQVSDRVRPANASGPSPQINTAVGRSLGFDQVHKNMNMPSSTSLSPAGTSKRNVRPETSNSGFGSGNKTGGWTSPFMSPGK
Protein: Collagen alpha-2(I) chain (Alpha-2 type I collagen) (Q01149)
Organism: Mus musculus (Mouse)
Function: Type I collagen is a member of group I collagen (fibrillar forming collagen).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
Interaction partners:
- Collagen alpha-1
- Collagen alpha-1
- Lumican
- Collagen alpha-2
- Integrin beta-1
- CD44 antigen
- Collagen alpha-1
- Integrin alpha-2
- Fibrillin-1
- Collagen alpha-1
Sequence:
MLSFVDTRTLLLLAVTSCLATCQYLQSGSVRKGPTGDRGPRGQRGPAGPRGRDGVDGPMGPPGPPGSPGPPGSPAPPGLTGNFAAQYSDKGVSSGPGPMGLMGPRGPPGAVGAPGPQGFQGPAGEPGEPGQTGPAGPRGPAGSPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGVKGHSGMDGLKGQPGAQGVKGEPGAPGENGTPGQAGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGELGPVGNPGPAGPAGPRGEVGLPGLSGPVGPPGNPGTNGLTGAKGATGLPGVAGAPGLPGPRGIPGPAGAAGATGARGLVGEPGPAGSKGESGNKGEPGSVGAQGPPGPSGEEGKRGSPGEAGSAGPAGPPGLRGSPGSRGLPGADGRAGVMGPPGNRGSTGPAGIRGPNGDAGRPGEPGLMGPRGLPGSPGNVGPSGKEGPVGLPGIDGRPGPIGPAGPRGEAGNIGFPGPKGPSGDPGKPGERGHPGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPAGPPGFQGLPGPSGTTGEVGKPGERGLPGEFGLPGPAGPRGERGTPGESGAAGPSGPIGSRGPSGAPGPDGNKGEAGAVGAPGSAGASGPGGLPGERGAAGIPGGKGEKGETGLRGDTGNTGRDGARGIPGAVGAPGPAGASGDRGEAGAAGPSGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGEKGTKGPKGENGIVGPTGSVGAAGPSGPNGPPGPVGSRGDGGPPGMTGFPGAAGRTGPPGPSGIAGPPGPPGAAGKEGIRGPRGDQGPVGRTGETGASGPPGFVGEKGPSGEPGTAGAPGTAGPQGLLGAPGILGLPGSRGERGLPGIAGALGEPGPLGISGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGSDGPPGRDGQPGHKGERGYPGSIGPTGAAGAPGPHGSVGPAGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGDKGHRGLPGLKGYSGLQGLPGLAGLHGDQGAPGPVGPAGPRGPAGPSGPVGKDGRSGQPGPVGPAGVRGSQGSQGPAGPPGPPGPPGPPGVSGGGYDFGFEGDFYRADQPRSQPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWNSDYYWIDPNQGCTMDAIKVYCDFSTGETCIQAQPVNTPAKNSYSRAQANKHVWLGETINGGSQFEYNVEGVSSKEMATQLAFMRLLANRASQNITYHCKNSIAYLDEETGSLNKAVLLQGSNDVELVAEGNSRFTYSVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGADQEFRVEVGPVCFK
Protein: Putative fatty acid elongase 1 (EC 2.3.1.199) (3-keto acyl-CoA synthase SPAC1B2.03c) (Putative elongation of fatty acids protein 1) (Very-long-chain 3-oxoacyl-CoA synthase 1) (Q9UTF7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May be involved in the synthesis of very long chain fatty acids.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Probable acyl-CoA desaturase
- Very-long-chain 3-oxoacyl-CoA reductase
- Putative enoyl reductase C646.07c
- Probable very-long-chain
- Putative fatty acid elongase 2
- Putative 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
- Uncharacterized MFS-type transporter C947.06c
- UPF0494 membrane protein C1348.01
- Copper-binding regulatory protein cuf2
Sequence:
MDLTGAHMLKIHRPSIDHPFGVDLWHLFEQLSIKTIGWNPSEFEYIPGKTPMSQWSSVIVSITAYYVIILSGRAIMTNRKPLKQRRLFQLHNFILTIISGALLALLVEEVFRNYMRNGLFYCVCDSRHFTQRLVTLYYLNYLTKYLELMDTVFLFLKKKPLAFLHCYHHGITALLCFTQLLGRTSVQWGVIGLNLYVHVIMYSYYFLAACGRRVWWKQWVTRVQIIQFVLDLILCYFGTYSHIAFRYFPWLPHVGDCSGSLFAAFFGCGVLSSYLFLFIGFYINTYIKRGAKKNQRKAAGKADNTSVAAAAGSEALAATTATNASPFSARSRKL
Protein: Fork head domain transcription factor slp1 (Sloppy paired locus protein 1) (P32030)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor involved in segmentation. Required for the formation of the mandibular lobe. Different levels of slp activity seem to be required in different segments.
Subcellular location: Nucleus.
Interaction partners:
- Segmentation protein fushi tarazu
- Protein tailless
- Segmentation protein even-skipped
- Fork head domain transcription factor slp2
- Homeotic protein empty spiracles
- Huckebein
- Homeobox protein homothorax
- Protein groucho
- Segmentation protein paired
- Zygotic gap protein knirps
Sequence:
MVKSEMEFKSNFSIDAILAKKPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRRKNPGASRTRLAAYRQAIFSPMMAASPYGAPAPSYGYPAVPFAAAAAAALYQRMNPAAYQAAYQQMQYQQAPQAHHHQAPHPAQMQGYPPQLNAELFQRMQFFGKFPSS
Protein: Uncharacterized protein (Q387J1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Transmembrane protein
- ATP synthase, epsilon chain, putative
- ATP synthase delta chain
- Uncharacterized protein
- ATP synthase alpha chain
- Uncharacterized protein
Sequence:
MSPKGIRYKPCTHFMSAKAAPKTLHQVRNVAYFFAAWLGVQKGYIEKSANDRLWVEHQRKVRQQNVERQQALDSIKLMQQGVRATTPGQLEGVPAELQQLAEAFTK
Protein: Oxidation resistance protein 1 (Q9VNA2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MEHAGAPISTSASNIATVLEDGENQQLPPLTGSGPSRQRSLRDRLKDGITGSFSWQSKSRSVDHGLAAPFDLDSLRSKVEQRFESVDKLSRQKSSLPTIPTISYTVGNRDTLTSVAARFDTTPSELTHLNRLNSSFIYPGQQLLVPDKSAKDDASSSSTHDADGASLSGKSSPVERKLSGDESREKDILEGLRPGSPKPGHIERVGGSSQQQQAEEEANKSDDPVITQRFLKINVRHITDGQGVVGGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPMELVVNAAIFHDIAHMRVAGGAGQGLNSASGDAEKPEIYYPKPVLVEEDSKELPEQQSLLGEDGNKRLDAEIGSLEIADDQESLCSSTGRDGDAFPKAFDRERVEDSSMEAKDSAKTDALDDEDKKAGLGLSSTRSTLEERRKSLLDHHWAIPSKDRYCLSNSRRSSEDEGDNESNVTVDSGARVQDPHSANSSVSGVPLSQPPVAAAAAAAAVAPASAVVPLPPSGIDLEHLEQLSKQSCYDSGIDIREPVPNVQPIPKKTVYSDADIVLSSDWVPPKTIVPTHFSESPPRSTILGQSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALAVTDKQADKKNKMLKRLSYPLTWVEGLTGEGGAVPPGGVGSGSLNKSGDTDSAPNTGDSNQSVFSKVFSSSPITLVSELGGNLFSKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTKLKEAKQAPKLDYRSMVSMDDKPELFISVDKLIPRPARACLDPPLYLRLRMGKPIGKAIPLPTSVMSYGKNKLRAEYWFSVPKNRVDELYRFINTWVKHLYGELDEEQIKARGFELIQEDTEWTKSGTTKAGMGGGSQDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYRKTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYRKMARLESPVLIVIEDTEHNVFGALTSCSLHVSDHFYGTGESLLYKFNPSFKVFHWTGENMYFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQEDFVIKTLECWAFV
Protein: Lectin (DrfL) (C0HK81)
Organism: Macropsychanthus comosus (Sea purse) (Dioclea reflexa)
Function: D-mannose/D-glucose-binding lectin with hemagglutinating activity towards rabbit and human erythrocytes. In rats, induces dose-dependent paw edema. Has low cytotoxicity against Artemisia sp.
Interaction partners:
Sequence:
ADTIVAVELDSYPNTDIGDPNYPHIGIDIKSVRSKSTARWNMQTGKVGTVHISYNSVSKRLSAVVSYSGSSSTTVSYDVDLNNVLPEWVRVGLSATTGLYKQTNTILSWSFTSKLKTNSIADENSLHFSFHKFSQNPKDLILQGDASTDSDGNLQLTKVSSSGDPQGNSVGRALFYAPVHIWEKSAVVASFDATFTFLIKSPDREPADGITFFIANTDTTIPSGSGGRLLGLFPDAN
Protein: Hydrogenase, iron-sulfur cluster-binding subunit, putative (Q729F0)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Heterodisulfide reductase, A subunit
- Heterodisulfide reductase, putative
- Hydrogenase, putative
- Heterodisulfide reductase, B subunit
- Hydrogenase, putative
- Heterodisulfide reductase, C subunit
- Rubrerythrin diiron-binding domain-containing protein
- Iron-sulfur cluster-binding protein
- Heterodisulfide reductase, iron-sulfur-binding subunit, putative
- Periplasmic [NiFe] hydrogenase large subunit
Sequence:
MPVLKGKELRVVGFLCNWCSYGGADTAGVGRFSQPTDLRIVRVPCSGRVDPLFIIKALISGADGVLVSGCHPRDCHYSHGNFYARRRLETLKSFLPALGIDPERFQYTWVSASEGQRWKNVVSTFVEKVHQLGHAPHIEDAVPYLPLAAAGDALRAPLRPLAYPPAGSLAQSLERLRERIRAALPELDCVIGWQQGYDALHATPLFMRKPEDVDKLTWGPLNVHNLATYLPQFKNRKVGVVVKGCDSRSVIELLQEKLIEPDNVRVFGMPCEGVVDVTQVQKALGTDDGGDHAGTAPASMSVEGDVLTVTGATPAQLKLADVVAEKCRTCDTPSPLLGEVVEGVASTPAGAPPAAPPGLDALDAMTPEQRRGFWRGQMERCLRCYACRNACPMCVCRDQCIGESRDPHWTTQEGNVREKLQFQIIHALHLAGRCTECGECQRACPVNIPVLALKQWMNRSVRDLFDYRAGMDVEAVPPLLSFAVEEKNIKEHGL
Protein: Large ribosomal subunit protein bL21m (39S ribosomal protein L21, mitochondrial) (L21mt) (MRP-L21) (Q7Z2W9)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042}.
Interaction partners:
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein bL36m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein uL18
Sequence:
MAASSLTVTLGRLASACSHSILRPSGPGAASLWSASRRFNSQSTSYLPGYVPKTSLSSPPWPEVVLPDPVEETRHHAEVVKKVNEMIVTGQYGRLFAVVHFASRQWKVTSEDLILIGNELDLACGERIRLEKVLLVGADNFTLLGKPLLGKDLVRVEATVIEKTESWPRIIMRFRKRKNFKKKRIVTTPQTVLRINSIEIAPCLL
Protein: Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (Q8GUN7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Adenylosuccinate synthetase, chloroplastic
- AICARFT/IMPCHase bienzyme family protein
- Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic
- Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial
- AMP deaminase
- Adenylate kinase 1, chloroplastic
- Adenine phosphoribosyltransferase 1, chloroplastic
- Phosphoribosylamine--glycine ligase, chloroplastic
- Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic
- Adenylate kinase 4
Sequence:
MELNLSSMATKIPCSGLIPIRSLLNPSKSLSHLPRVSFSVSSPHSLKLMTSTKLIAMASASSRDFEMSNLTALSPLDGRYWGKVKDLASSMSEFGLIYFRVLVEIKWLIKLSNIPQVTEVPSFSKEAHKYLQGIIDGFSMDDALQVKKIERVTNHDVKAVEYFLKQKCESHPEIAKVLEFFHFACTSEDINNLSHALMLQEALSSVILPTMDELIKSISLMAKSFAYVPMLSRTHGQPASPTTLGKEMAIFAVRLSVERRYLSETKIKGKFAGAVGNYNAHISAYSNIDWPHVAEEFVTSLGLTFNPYVTQIEPHDYMARLFNTISQFNNVLIDFDRDIWSYISLGYFKQITKAGEIGSSTMPHKVNPIDFENSEGNLGKANAELAFLSMKLPISRMQRDLTDSTVLRNMGGALGHSLLAYKSAIQGIGKLQVNEARLKDDLDHTWEVLAEPIQTVMRRYGVPEPYEKLKELTRGRAVNEESIRKFIKSLELPEEAKDQLLKLTPHTYVGAAAALALAVDDAVHLGH
Protein: Cycloserine biosynthesis protein DcsG (EC 6.3.3.5) (D2Z030)
Organism: Streptomyces lavendulae
Function: Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent. Catalyzes the synthesis of D-cycloserine from O-ureido-D-serine (D-OUS). It reacts with D-OUS, D-homocysteine and beta-aminooxy-D-alanine.
Interaction partners:
Sequence:
MGILALVTDAVSLPIDYDMPPLLEACRTVGITAEVCDWEDGTVDWSRFEAVVFRSPWTWAERQAEFLAFCERVSHVTRLITPMPLVRWALDKRYLADLAAHGVPVIPTTVVAPGSDALAAVRDFLAARPEAREFVVKPTDGCYSKDVQRYQRSLAEPASRHVARLLANGSHVILQPYVESVDRHGETDLTFFDGVYSHAIHKGAMLMPDGTVHVPTLDFRQARDADEDQRAVAAAALAASVAHLGLDLPLVCGRVDLVRGADGSPMVLEMELCEPSLNLTFSEDGALRFAQALAERLKP
Protein: Beta-1,3-glucan-binding protein (BGBP) (Beta-1,3-glucan recognition protein) (BetaGRP) (BetaGBP-HDL) (High density lipoprotein) (P81182)
Organism: Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei)
Function: Involved in the recognition of invading microorganisms. Binds specifically to beta-1,3-glucan and activates the prophenoloxidase cascade.
Subcellular location: Secreted {ECO:0000269|PubMed:9149399}.
Interaction partners:
Sequence:
MSFDLTTPFDVIKTVSLSARYSWTTSQKGATLNITYNDKNFVLSSSLQLSTRASNITFQATTPFEGFQNSFIEIKYDIDNREELLASRVSVDDHSYSFVVGGYIEDKLAVFKWNLNSPLTGWTDAKFVAKIDLSSENKNLEISLEKEGDLKAIAVSGKFIGSTLDFNLRTPFRGLNNFNVFGSLNRSKRSLEMRMMNDAGQASLAGNFNSLRFNMKTPFERAEQISWEVTKTGEGSYKAEWRRNDNYATFTIEKDVSKQSFDLNIKSEFRGWEILALTGRLDQETKQAYLSGAINEQKITVTGSGSITNKIKFSMTIETPYENYRQVKAQLNYAKRKNAIKLEASSSSSDFHLLWSRSGSGLEAHLIVPNSRQNTEISINLTPTQGKITITSRFEPIRDYLQEYHVNLGQNEITADHIIKLNGHEVFKMDFERNAPEQKVHLEIHTHVAERHTTIHFHREGFSKLNFLFKREVPQYGEKHFKVDITGSGALPQKGALDIVVENTFREPAKTINARVEVDRTGARKKIMLEVSPRQSRVYIFNLEYIADLESPQHGDFTLKITTPNNSPWQNISGNWNVEDPNDATITFTVGNVTYNAKGKLTLRESTMILSSTDPSAENIYLQWKFERNGDTKDYFLKLGRKSRYGMLKLTGTITDIAHVDIEGGFKAGPFMPNEFLFTSMWGKSNGVVTGEGTFDYGNYHGSHRLVKFERNAERKSASFEWSATSNIPQYNSVSVSGNYDFNHKVVIFVVINADGRESKIDINIADINPTSSRNTAMISIPLLGPTFKRTELTVSHDFSHPNRKSISAVAKFGRSESFINAKWNRSDGFDTLEGNIEAKSRFLGDFLINVRYDMSNIADAHAEVDYLRTTTDGDKKEFKLNWTRKSTDDHLENEMVFDSNFETLSHARAYANADYGGIFKLLSGLDWDDKKISLTLEVRKNKISGILTTPFEGFETLEIDLQYKLTGKDKSVKATYQRGDRKASFNMEMSTKGKKGGSFKVDLTTPFEVVKNLHIDGQYENKVAQINYQRNDIQMNFNGKANIKSSKASFDISFTPPSGQNIRIAASYDVQDFIDGTGDEEKELASLSLEFEGNSMDFSLHGFRNDDRLYVMIHGTSSFAVLKMFHLKLDSELNTEARDGTFELTFNDFKFNVSNHFERRANNGYYFRSKIESTLTPLPALIIGLGREGQERIITIGYGEDKEITFSVKGKNNFLSGFSGKVDIPSIGYEGVEYDVDYSFPGDNHLQIKVEIDLNENGQEVEATFFLDSEGIKARLSSAVLGDHSLRVRRSVAPDGFYAEAGLDDYNLKLRGGFKNEDTARGVQLEGEVFGKRFLIDTLFQSEGKRYSEGKLIIHTPFHGMEKMGGLFTWSNQNKKIMAHAELHLPSYTTPTITGEISLDLKKKINGYVTLDVAGEEFTLKCNLAGSSISQGYTGSLEFYTTIPCCITCCGDR
Protein: Microtubule nucleation factor SSNA1 (CrSSNA1) (13 kDa deflagellation-inducible protein) (Q9XF62)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Microtubule-binding protein which stabilizes dynamic microtubules by slowing growth and shrinkage at both plus and minus ends and serves as a sensor of microtubule damage (By similarity). Induces microtubule branching which is mediated by the formation of long SSNA1 fibrils which guide microtubule protofilaments to split apart from the mother microtubule and form daughter microtubules. Required for cell division.
Subcellular location: Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000269|PubMed:12640030}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:12640030}.
Interaction partners:
Sequence:
MSAQGQALQNHNNELVKCIEDLREKREEIIKQLREDDAEKAKITQELQILTKRLAQVNESIARKTETKNEYDKVISETEAAYLKILESSQTLLTVLKREAVNIAKKKQASS
Protein: Caldesmon 1a (Zgc:171553 protein) (B0BLV5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDDDFERRRELRRQKREEMRLEAERMAYRRSEEDEEEAARERRRRARQERMRSKDSEDVAFQPETPELNNSHSVTVSESISTSVLSSSGTGEGDEEEQALLERLAKREERRMRRMKEALERQKEDEEESSSSSLRRGRSYEPEEHHNNNNNQEEKEEEKQEEEEEEEDVRCREEEEEEEQRVEEKQQRSYLRERMEDEDVMRKNKQPNGGVCEDSPPKHKKAERTFSRGSLRSPEAPDADDEDARLEAERKLEELKRRRDEMESEEFEKMRQKQQEAEVELEELKRKREERRKVLEEEERRRKQDEADRKTREEEEKRRMKEEIEKRRAEAAEKRQKVEDSVDGEARKPFKCVSPRGSSLKIGERAEFLNRSAQKSSVKASHTPVVSKIDNRLEQYTIAVQGNKEVRSPRSGAIDLPMVTDGIRNIKSMFEKGNVFSSGGSPASTNKDAAGIKVGVAGRINDWLNKTPETGKMSGGRPADLKPGDVTSKRSLWENKGSSATKVTSRGETKSVTNGMGH
Protein: Enolase (DUF1399) (Q9C7J8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized protein
- Heterogeneous nuclear ribonucleoprotein 1
Sequence:
MSLERSEFVDGVAARSLSEISEVDAVRIGGDIISSARRLIALLRSVGDCQWLHHPPVIAEAIRRYDELWMPLISDLTVGLKPPMILPPLDVEWVWFCHCLNPVSYSDYCERRFSKLIGKPAIYDEENEDYAVLQCEKIWSLRYPLESFENRADPDSLETVSLVNEDIKSLVKKQMFLWEKFSAPYMSETVYLIAARLRYKGFLLILHKFKDEVSSLIPASDILLMWLTHQSYPTVYKDDVDEMLEEMTRKVVQVGEKVEKTEVETTKELWDRYFNQPYEKAGGELSIIANESGLSNNTMFYWPVSDMDVNTAYKSIRPRFVLELCIFLRLNPKAEQNESIDRSFLRLRVARCHRKLQLDKKMTDLSSEASWQKAWHLYCEFGTLGFILESHCDRSRGICFKSGKPEGMIEFPWNDLLRAHSLASGRFLGKQVSVFASVTPPVQAPYLLRFVPDRVTDDSGAMISDSVQRTNNFRPQEGRWLTRTVLDHAGRECFVIRIRVGKGVFKRGGEVPSPVKSEERITEVRVGSWSYVEGSIGKAPAKVVGTVTPKEPMEDWEAAWEFSTGDELCIRWDSLGTISELRLYSRNPGSLVRLLTGRRMQYKGEDEEDDEGFVTVVRSTEEDPTEKATALIDWKHQAVEFLPEEDAVFVLLLSVSILRSVTHKRREDVGKLLVRKRITEATGERDWGSVIVDASSTNVSSSSSPYVEPWYRNSGKVMAMEEKAQVARYPYPVMSYSNVDGGDNLYKHVIFG
Protein: Chromatin modification-related protein eaf6 (O14240)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mst2 complex subunit nto1
- Enhancer of polycomb-like protein 1
- SWR1-complex protein 4
- Probable chromatin modification-related protein eaf7
- Histone acetyltransferase mst2
- Chromatin modification-related protein png1
- Chromatin modification-related protein eaf3
- Protein AF-9 homolog
- Pdp3-interacting factor 2
- NuA4 acetyltransferase complex subunit Tra2
Sequence:
MSTPNSTPSEPPVNVSYYEQCKKELHEMIEKRQLLETSLIGLEDSIYRLEGSYLEKTSGTGNIIRGFEGLLKNNASNLRRRADYSESDRLFSLSSLSSPHTRSPAYDLDDSTETSRRRKRKNESDSHEGRRRSSFREL