wanglab/gogpt-training-data huggingface dataset:
Protein: Down syndrome cell adhesion molecule 1, isoform AI (Q0E9K2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVNQFYEAEIMTEYVIRGNAAVLKCSIPSFVADFVRVESWIDDEGNVLSFSDNYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGTVSPKISTGEDFKHLKGKSSQDLSILCPAQAYPQPFFRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPSIAPFSFGDDPVNTGENAGVQCMVQKGDVPITIKWTLNSRPIINGEEGITILKLSPKTSVLNIAAVEQDHRGVFKCIAENKAGSSFTTSELKVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (Q8CDM1)
Organism: Mus musculus (Mouse)
Function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Estrogen receptor
- Lymphocyte-specific helicase
- DNA topoisomerase 2-alpha
- DNA replication licensing factor MCM4
- WD repeat-containing protein 76
Sequence:
MSLLKMRRHAIHSSDSTSSSSSEDDCFERRTKRNRNRAINRCLPLNFRKDEIRGIYKDRMKIGASLADVDPMQLDTSVRFDSVGGLSSHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSRGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPAIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDKNARKEILKIHTRDWNPKPVDMFLEELAEHCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSITISAKDFEAALQKIRPASQRAVTSPGQALSAIVKPLLQNTVHRILDALQKVFPHVEVGTNKSLNSDVSCPFLESDLAYSDDDTPSVYENGLSQKENLNFLHLNRNACYQPMSFRPRLLIVGEPGFGQSSHLAPAVIHALEKFTVYTLDIPVLFGISTTSPEEACSQMIREAKRTAPSIVYVPHIHLWWEIVGPTLKATFTTLLQTIPSFAPVLLLATSEKPYSALPEEVQELFTHDYGEIFNVQLPDKEERTKFFEDLILKQASKPPVSQKKAVLQALEVLPVAPPPEPRPLTAEEVKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLKDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESRKKRGCSSSKYAPSYYHVMPKQNSPPVGDKKPDQEQNEKLKVPCTPVACSTPAQLKRKFHKKSKWHVGTKIKRRKISQAKDNSLNAMNSSSRSDTEDSQHTHAEHTEPGNTDESSVEESDKQNRLESNIDLKNNSSSSNIENELEEPKETTEGTELRKDRIVCRGDASASQVTDIPEDSESKEMDFLRMTLARGSQVEQQELISMEQALAILSQPTPSLVLDHKQLTNILKTVVKKSQKYNIFQLENLYAVISQCIYEHRRDYDKTALVQKMEQAVENFNCSRS
Protein: Probable glutathione S-transferase 6 (EC 2.5.1.18) (GST class-sigma) (P91252)
Organism: Caenorhabditis elegans
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Interaction partners:
- Glutathione S-transferase omega
- Glutathione S-transferase P 10
- Glutathione transferase omega-1
- Glutathione S-transferase omega
- Probable glutathione S-transferase gst-36
- Probable glutathione S-transferase 5
- Glutathione s-transferase kappa 2
- Glutathione S-transferase
- Glutathione synthetase
- glutathione transferase
Sequence:
MVHYKLVYFPLRARAEIARQIFAYAGQDYSEENLSFEQWPARKNNTPFGQLPILEVDGKPLGQSYAIARYLAREFGIAGQNDTEAAEVDAIADQFKDYLNDVSPYLTVLAGFKPGDKDQLRTDVFVPAFKKNFEFFENILASNHSGFFVGNSLTWVDLLISQHVQDILDKDLAVVEEFKKVLAHRKKVQSIDRIQKYIANRPDYPF
Protein: Thrombomodulin (Q8HZ48)
Organism: Oryctolagus cuniculus (Rabbit)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MLRALLLLLGALAPAGLGLPTHAEPQPDGSQCVEHDCFALFRGPATFLAAGQTCERLGGHLMTVRSSVAADVISLLLSDDSPRLWIGLQLPTGCSHPGDLRPLRGFQWVTGDNRTSYSRWARQDGGGAPVCGPLCVTVSAASAAAPGEPAWEELPCGTEVDGFLCEFPFAASCRPLLVEAGAAPATAPHVSSTYSTPFGARGADFQALPVGSSAAVAPLGLELTCYAPPGAAEARWGREAPGAWDCSVGNGGCEFACNASAGAPRCLCPDGAAPQADGRSCAPAAPPSCHDLCEHFCVRTSDASGSYMCMCETGYRVAADGHHCEDVDDCALVPNPCPQLCVNTQGGFECHCYPGFDLVDGECVEPLDPCFGTNCEYQCLPLGQNYRCICAEGFAPVPDEPHRCQMFCNQTTCPADCDPNYPSTCLCPEGYILDEGSLCADIDECDNGYCQDECRNLPGSYECICGPDSPLAGQVSTECYPTQVSDGGDGGDDGGSGEPPGSGAPGSTPAPPPAAGPVHSGVAIGISIASLSLVVALLALLCHLRKKQGSGRAELEYKCASPAKEVVLQQVRTERTQPKP
Protein: MAGE superfamily member protein (Q9ND98)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASTSRARRSQNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVAGDKSELKKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVASIHDVTPAQRPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNTYPDEEQGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE
Protein: Furrowed (P91658)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MWPFSWWVWRAASVCARWRPSANDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGHLVHDFRGATSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNGDVVQKPTWGKDQPNNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDGWSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGSTATYFCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTTTVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETPSVPSGSFVIGYDYNVHSKIQYNCDPGHIMDGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTNTTYVGSEVGFSCSQSHKLSGVLKRTCLESAVWSDASAKCEEIRCPEPKLPAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYRIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFLYRNKARPAKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGGAGGRSNGGGNPDANSNGERLNNNRSENIYDQIPNEQFYDAPYEMRTNDEVYEPEPVASNVITINGFPSDRDRYLYRYRYLYQYNFVLISKSKGMAELIDKR
Protein: COP9 signalosome complex subunit 3 (CSN complex subunit 3) (SGN3) (Q9UT51)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 7
- Cullin-4
- Ubiquitin-like protein 1
- COP9 signalosome complex subunit 2
- Eukaryotic translation initiation factor 3 subunit H
- DNA damage-binding protein 1
- RING-box protein pip1
Sequence:
MVANMEFQGTLPFHPLEDPETLLLKFTDFVHQHSVEQCNQLSMYIIASVNSLAEAFYGSHPEKYNIVFQSVEYAAHSPAISVMHVCYLKELLRQGQYATSLKSFNDLEVSKHIPGSILLQYCMYAAYHCLGNNDLDSAKVWYFSILYIPTTTLTSFHEEAYYSFLLLYIITTGKKFQLDSATSSNVLPLKRHMVPYEEFLDAYLKDVNTLRTVIKEHWSRFLKDNSTAFILFALEVYPMHRLKKWRKTFSSLKLEYIAKQLAISQDVAKEIIQKFDNKTNFTVANGEIFLTFNALDDVSPEMHSDLCQQLIEASKNFEASIRLKSVIYSKIMAKKLNA
Protein: Small ribosomal subunit protein eS4A (40S ribosomal protein S4-A) (RP5) (S7) (YS6) (P0CX35)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein eS17A
- Small ribosomal subunit protein eS26B
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein uS8B
- Periodic tryptophan protein 2
- Small ribosomal subunit protein uS14A
- Small ribosomal subunit protein eS30A
- Protein LTV1
- Small ribosomal subunit protein eS27B
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL
Protein: Ribosome biogenesis protein brx1 (Q9HGL6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for biogenesis of the 60S ribosomal subunit.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}. Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized RNA-binding protein C1827.05c
- Ribosome biogenesis protein erb1
- Probable rRNA-processing protein ebp2
- 60S ribosome subunit biogenesis protein nip7
- Ribosomal RNA-processing protein 1 homolog
- Ribosome biogenesis protein ytm1
- Brix domain-containing protein C4F8.04
- Probable nucleolar GTP-binding protein 1
- 25S rRNA
- ATP-dependent RNA helicase has1
Sequence:
MSTVYKLKTSERAPKNEDEDEEYVPVQNGQGNKHSAGFVPIKQKVLVLSSRGVTYRQRHLLNDLVSMMPHSKKDSKLDSKDRLYQLNELAELYNCNNIFFFESRRREDLYLHIARAPNGPTVKFHVENLHTMDELNMTGNALKGSRPILSFDKTFDTAPHLKVVKELLQQTFGIPKGARRSKPFIDRVCTLTIADGKIWFRNYEIRENEDKSKDPVTLIEIGPRFVMTIINILEGSFGGPVIYKNDTFVSSTMVRAAIRNQAAQRYVNRQESKLERQVRAQQNVIPEDPLDNVFA
Protein: AT5g52550/F6N7_3 (Stress response NST1-like protein) (Q940C2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDSSSSMCKQAQPIVRKARKKKVKGVVDPIKQAEKKNRRLEKAIATSAAIRAELEKKKQMKKEGQLEAADEEDSADAAKKKQERDELERIKQAENKKNRLEKSIATSAAIMAELEKKKLRKLEEQKRLAEEGAAIAEKKKRRLEKAIATTAAIRAELEKKKQMKKEGQLDAAVEEDSAYAAKKKQEREELERIKQAERKKRRIEKSIATSAAIRAELEKKKLRKLEEQRRLDEEGAAIAEAVALHVLLGEDCDDSYRNTLNQETGFKPWDYTTKINLFSGGINRFFPHQRCSSYAVHDNNRTRDSNWSSVSYEPFARGWDNNNNNMGISADLFDTQAVSSLQISENTDVDAIVFNGMFRR
Protein: Two-component response regulator ORR1 (Type A response regulator 1) (OsRR1) (Q4GZL0)
Organism: Oryza sativa subsp. indica (Rice)
Function: Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
Interaction partners:
Sequence:
MEGGRGVTRVLLVDDSPVDRRVVQLLLSSSACAGSFHVIAVDSAKKAMEFLGLKEEGKEQAIDMVLTDYCMPEMTGYELLKAIKALSPLKPIPVIVMSSENEPQRISRCMNAGAEDFIVKPLQSKDVQRLRKCSPANTQCCDAGSDGKPPLLLLPSDHVVVDATAASPPPPPSRRRAHFAGVAMVLHSSSVELSHYFPFLFKFILLVYAILCLGELLHRWSNGCFLNLWCA
Protein: [histone H3]-lysine(36) N-trimethyltransferase (EC 2.1.1.359) (SET domain-containing protein 2) (A0A8I6A5I9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
GLNNTKSSLPKKKEENKKRTAKIENVQKTGFIKGPIFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFFTALSNEKQSDSPHSPATPQVDSNPKAKMEAGDTFPATEESSPPKSRVELGRIHFKKHLLHVTSRPQLATTTTVASLLPPTTQLPVAIAESTVDSPPSSPPPPPPPPQVSSPSPPAPISEPVALPHPPVTALMTSTPGPLPVDAAVRAQKEPPMKSVPESLELDMKQDIVSNSLEEHTNQTLKEQADNALQKEDSHIGKEEEVSDGSKISLSSKKASSKKKSSQFEGTFLGSESDEDSVRTSSSQRSHDLKSSTSIEKERDFKKSSAPSKSEDLGKSSRSKTERDDKYFSYSKLERDTRYVSTRCRSERDRRRSRSRSRSDRVSRTSLSYSRSERSHYYDSERRYHRSSPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRTSAHSYRDLRTSSSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSEHEAIKRCCSPPNELGFRRGSSYSKHDNNSTSRYKSALSKSISKSDKFKNSFCCTELNEENKQSHSFSLQTPCSKGSELRTINKIPEREKTGSPSPSNQLNDSPTFKKLDESPILKPEFIGHDSHESIKELELPKMKNDQLRNFCSIELNVNGSPETETDVATFRTSKPDAISMTSDDSVTGSEVSPLIKGCVLSSNGFQSVGRCRERDADDACRQHNKSKSPFRETEPLLSPHHDKVMSLPVKTIDYSKTLIKEPVDKRHSCCKTKDSDRYCSPNESSEAENREISSNCFVNVHLDSKTVVCDNRELTDQHSEFTCDGYKQSIGSTSSASLNHFDDLYESVGSSGISSLQSLPSGIRCEENTSPALDTVQSKKGIDFLKYVGKETDVVSALPDSGKAFSSWENRHNMLSGQSLQESQEEGSSTLHERRGRSEVSLDEEEQRGHTHISDDSEVVFPYDLNLTMEDSDGVTYTLKCDSSGNAPEIVSTVHGDYSASSASSSDESDSEDTESDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDGLESRRHAYEEKFESMASKGCSQTEKFFLHKGTERNPETSYSQFSRKIDNHLPEIAHSQSDGVDSTSHTDVKSDSVGHLNSEDAIRAKMSRPQELPVYCDDFEDLPNTSRQQMIFSNRPDSSRLGKAELSFSSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSAEHYGGTHDYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREEEENWDQRSGSHFSSPSNKFFFHQKDKGSVQAPEISSNSIKDSLVINERKDFSKNFEKNDIKERGPPKKRRQELESDSESDGELQARKKVRVEIEQGQSSVPQHSELVGPSCAMDDFRDPQRWKEFAKLGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEVDTDTPKKLIFRRLKIISENSMDSAVSDVTSELECKDGKEDLDQLETVTVEEDEELQSQQLLPSQLCESKVESESTIDVSKLPISEPEADTETEPKDSNGTKLEETIAEETPSQDEEEGVSDVESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKESTVTERGRDTAAFRDQTAPKTPNRSREREPDKQSQNKEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPFDSLGYNASHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTESLAAPPSVPVVPHGAASVEVSSSQYAAQSESVVHQDSSVPGMPVQTPGPVQGQNYSVWDSNQQSVSVQPQYSPAQSQATIYYQGQTCSTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPPEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKTSKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE
Protein: Homeobox-leucine zipper protein ATHB-X (HD-ZIP protein ATHB-X) (Homeodomain transcription factor ATHB-X) (Q8GXM7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MALSPNSSSLDLTISIPSFSPSPSLGDHHGMRDFDINQTPKTEEDREWMIGATPHVNEDDSNSGGRRRKKLRLTKEQSHLLEESFIQNHTLTPKQKKDLATFLKLSQRQVEVWFQNRRARSKLKHTEMECEYLKRWFGSLKEQNRRLQIEVEELRALKPSSTSALTMCPRCERVTDAVDNDSNAVQEGAVLSSRSRMTISSSSSLC
Protein: [histone H3]-trimethyl-L-lysine(27) demethylase (EC 1.14.11.68) (F1Q597)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKSCGVSVAAVARAAAAAAAGGDEEKKMAAGKARETEEDFPKLTPQERERLASIDSTLFGFQRLHEDGARTKALLLKAVRCYDVYILKAEGKVEPEVFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFRWAVQLTPSDAQSGQRRAIKAFQEVLYIDPCFSRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDSTPCTLSKAEIQFHIAHVYEIQKKYRIAKEAYESLLQTENLPAQVKATTLQQLGWMHHTVEQLGDKANKNSYAIQCLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHSHAAAWMDLGTLYESCNQPQDAIKCYINATCSKSCSNIPALTARIKCLQAQLCNLQQGSLPSKSKMLPSIEEAWSLPIPAELTSRQGALNTTQQQTTCKAHQSNEAQSQIPSQSLPPHVLSGQTEDQSSPAKKKRTTSPARNSSDSWTNDPGHHQISNWSLTPQKLQLLEQLRNNRANLKPVQLQMLEQLEKQLSLMQQNQQTRLNAMGQIRPSVSNGPVADSSLPTNSNSTPSPHHPHIALSRTPSALTRCAAQPIANGPVPASPVPCSTAGTLGNTDAVSVGNNHLPGSGSNGNVPYLRQNALPHNCTTPTSSSMDDEQWKSQHINSTQGLQKSPGSYSAGPNGEQPFSSTGTSQPSPAAGTGGPNQVGHSATASDTQAQEASHNHLPSPSSQSSATSGGQQGTVNTKESKPSGNGHSVGTPNSTATAEGLPNHVHQGQADTAGAKPRSPGVLSSDNPQLSALLIGKANDSNNSNGGGSAAAGTKVNNVHPSLHKPQENSVASSPCSAMSAASPSPKTADHHSTQNSVNSLNSPTLNGKGLEDSQSPLKVASPLVCHKPTPPSFTLWSSVSIYPSSSDVLKACRNLGKNGVSNNSILLDKCPPPRLPPPPIPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNTANPVTVIRGLAGALKLDLGLFSTKTLVEANPEHLVEVRTQLSQPTDENWDVTGSRKMWRCESSRSHTTIARYAQYQASSFQESLREENEKKGQKDHSDTESAPSENVVRRRRGPFKHIKFGTNIDLSDEKKWKLQLAELSKLPAFARVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVPEPYWGVMNDFCEKNNINYLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWLNTGTVHWVQAIGWCNNIAWNVGPLTVHQYKLAVERYEWNKLQSVKSIVPMIHLSWNMARNIKVSDHKLFEMIKYCLLRTLKQCQMLREALIAAGKELVWHGRTKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQGCARRCSPNLDNFVVLEQYKIDDLMQVYDQFTLAPPLPSSSSS
Protein: Putative secreted protein (O87990)
Organism: Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Interaction partners:
Sequence:
MIRKSYIIGLLLTLLLGSGLGGYALQRATSATPAATDATAKPAAEPATREVEKSNESPPPAGLATPSGYDGGQLPCMQKESMERYACLVRTAGEGAANVTPGGKGEAAGASPLTQMFMVTEAMNLIRTLASSARYSWNQSTLGAGFIKPNMAQQEICLDGGFGICGNHQYLFLELMHRLGLEARSVGFWYIDPNANSRASHAAAEVLVDKKWRYVDITWGSLWLAQRNDLLSAMSLDEVLAGKGHRFTGTTDVWYIAQRMAKYDPFIYLKGRDLQVTRDGGGLLQIKLADQAEKFAHMPNYVGTVPERATMEMQISSNHKHTELQVNISGMAGCKQSRLQIGDEEFDIRPGTILTNTFQQQDRISVQGSDPHCYVVLSSIEPIRSAKRASAPN
Protein: (human) hypothetical protein (B3KN02)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MYQISKNSGWARSREYNFNLKTQSILFNRHKEDLQPYKYAGYPMLIRTITMETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGLEVLQEAFSRCVAVLTRSSKPSDMSVQVCGYISKCYSVAAQFEECREKITEMPSIIKDLCRVLYFGKSIPRVAALGVECVSSFAVDFWLQTHLFQAGILWHLLGFLFNYDYTLEESGIQKSEETNQQEVANSLAKLSVHALSRLGGYLAEEQATPENPTIRKSLAGMLTPYVARKLAVASVTEILKMLNSNTESPYLIWNNSTRAELLEFLESQQENMIKKGDCDKTYGSEFVYSDHAKELIVGEIFVRVYNEVPTFQLEVPKAFAASLLDYIGSQAQYLHTFMAITHAAKVESEQHGDRLPRVEMALEALRNVIKYNPGSESECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQDCVNNIAESMVLSSLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMAKGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLIGPKVRITLMKFLPSVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSRDKVSTTVREMMLEHFKNQQDNPEANWKLPEDFAVVFGEAEGELAVGGVFLRIFIAQPAWVLRKPREFLIALLEKLTELLEKNNPHGETLETLTMATVCLFSAQPQLADQVPPLGHLPKVIQAMNHRNNAIPKSAIRVIHALSENELCVRAMASLETIGPLMNGMKKRADTVGLACEAINRMFQKEQSELVAQALKADLVPYLLKLLEGIGLENLDSPAATKAQIVKALKAMTRSLQYGEQVNEILCRSSVWSAFKDQKHDLFISESQTAGYLTGPGVAGYLTAGTSTSVMSNLPPPVDHEAGDLGYQT
Protein: Agamous-like MADS-box protein AGL103 (Q9LSB2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that may function in the maintenance of the proper function of the central cell in pollen tube attraction.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
Interaction partners:
- AGAMOUS-like 102
- AGAMOUS-like 39
- Agamous-like MADS-box protein AGL92
- Agamous-like MADS-box protein AGL13
- AGAMOUS-like 96
- Agamous-like MADS-box protein AGL30
- AGAMOUS-like 67
Sequence:
MASSSSSSLSFSTSKKNKTFFKKPNSAFSSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGELKTWPEEREKVKAIARRYGELSETKRRKGSVDLHEFLEKMNKDDPEKEEKKKIKVRRVPKVKYPVWDPRFDNYSVEQLMGLVQSLERNLTRIQHRTCAVVEAQGQRRVQYTNMANQELMMANTMNQLQQHSNQVSMYLWNHGNGAFSQIPVSALASNQTQSLAPIPPELMIYPNSDAGNYSGSLGVQGTGINGLQNMNMLTYNNINSVNDFSKQFDQNSRAESYSSLLGVHEDGNNEFENPNMSSRNNFNVQDCAGLLGMQGAGTNGLQSMNMHDYSNNNSINSNGLSHQYVQFPTYNSQHQDRVFNLDQNGNNTRSL
Protein: Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (Q5XIP6)
Organism: Rattus norvegicus (Rat)
Function: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
Subcellular location: Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03140}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03140}. Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03140}. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage. {ECO:0000255|HAMAP-Rule:MF_03140}.
Interaction partners:
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- Proliferating cell nuclear antigen
- DNA ligase 1
- DNA polymerase beta
- DNA polymerase delta catalytic subunit
- DNA ligase
- DNA replication ATP-dependent helicase/nuclease DNA2
- DNA repair nuclease/redox regulator APEX1
- Double-strand break repair protein MRE11
- DNA polymerase delta subunit 2
Sequence:
MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYIFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGAEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESVRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPENWLHKEARQLFLEPEVLDPESVELKWSEPNEEELVKFMCGEKQFSEERIRSGVKRLNKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGPAKKKAKTGGAGKFRRGK
Protein: C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (MIP-1 alpha receptor) (CD antigen CD195) (O08556)
Organism: Rattus norvegicus (Rat)
Function: Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- C-C motif chemokine 2
- C-C motif chemokine 5
- C-C motif chemokine 3
- C-C motif chemokine 4
- T-cell surface glycoprotein CD4
- C-X-C motif chemokine 10
- Eotaxin
- C-X-C motif chemokine
- Stromal cell-derived factor 1
- Macrophage inflammatory protein-1 alpha receptor
Sequence:
MDFQGSIPTYIYDIDYSMSAPCQKVNVKQIAAQLLPPLYSLVFIFGFVGNMMVFLILISCKKLKSMTDIYLFNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKLFTGIYHIGYFGGIFFIILLTIDRYLAIVHAVFAIKARTVNFGVITSVVTWVVAVFVSLPEIIFMRSQKEGSHYTCSPHFLHIQYRFWKHFQTLKMVILSLILPLLVMVICYSGILNTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLLLTTFQEYFGLNNCSSSNRLDQAMQVTETLGMTHCCLNPVIYAFVGEKFRNYLSVFFRKHIVKRFCKHCSIFQQVNPDRVSSVYTRSTGEQEVSTGL
Protein: Glutaminyl-tRNA synthetase 1 (A0A0U1RRI9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAALDSLSLFTSLGLSEQKARETLKNSAQQTLGSTIDKATGILLYGLASRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPKLEADLEKKFKVAKA
Protein: HTH-type transcriptional regulator PtxS (G3XD97)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Negatively regulates glucose metabolism by binding directly to the promoter region of the kgu and gad operons. It also negatively regulates its own synthesis.
Interaction partners:
- Probable 2-ketogluconate kinase
- AP endonuclease
- HTH-type transcriptional regulator HexR
- phosphoenolpyruvate--protein phosphotransferase
- phosphoenolpyruvate--protein phosphotransferase
- HTH-type transcriptional regulator PtxR
- Exotoxin A
- Glutamate synthase large chain
- Gluconate permease
- Probable 2-ketogluconate transporter
Sequence:
MNGSVLPSRGRVTINQVAEAAGVSKASVSRYIGGDRQLLADATARRIERAIDQLDYRPNQMARGLKRGRTRLIGMLVADILNPYSVAVMHGVETACREHGYSLVVCNTDRDDEQERHHLAALQSYNVEGLIVNTLGHHPGELRALHRELPMVLVDRQLAELDTDLVGLDNADAVEQALDHLQHRGFRDILLVTEPLDGTSSRIERVQAFNASIGRRPALKGQVLQTDDFFRDGLRAFLSASGPGPKALFTCNGVATLCATRQLRDLGCRLFDEVGLLALDELDWYPLVGSGITALAQPTDEIGRTAFERLLARLEGDREPARRVTFPAQLIVRGSTHPRG