wanglab/gogpt-training-data huggingface dataset:
Protein: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) (P00492)
Organism: Homo sapiens (Human)
Function: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
Subcellular location: Cytoplasm.
Interaction partners:
- Adenine phosphoribosyltransferase
- Purine nucleoside phosphorylase
- GMP synthase
- Inosine-5'-monophosphate dehydrogenase 2
- AMP deaminase 2
- AMP deaminase 3
- Adenylosuccinate synthetase isozyme 2
- AMP deaminase 1
- Guanine deaminase
- Bifunctional purine biosynthesis protein ATIC
Sequence:
MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
Protein: Photosystem II reaction center protein Z (PSII-Z) (P0C430)
Organism: Oryza sativa subsp. indica (Rice)
Function: Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00644}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00644}.
Interaction partners:
- Photosystem II CP43 reaction center protein
- Photosystem II reaction center protein J
- Photosystem II reaction center protein H
- Cytochrome b559 subunit alpha
- Photosystem II reaction center protein I
- Photosystem II reaction center protein K
- Cytochrome b559 subunit beta
- Photosystem II D2 protein
- Photosystem II CP47 reaction center protein
- Photosystem II reaction center protein T
Sequence:
MTIAFQLAVFALIVTSSVLVISVPLVFASPDGWSNNKNVVFSGTSLWIGLVFLVAILNSLIS
Protein: Sentrin-specific protease 2 (EC 3.4.22.-) (Axin-associating molecule) (Axam) (Sentrin/SUMO-specific protease SENP2) (Q9EQE1)
Organism: Rattus norvegicus (Rat)
Function: Protease that catalyzes two essential functions in the SUMO pathway (By similarity). The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins (By similarity). The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein (By similarity). May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1 (By similarity). Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (By similarity). Acts as a regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS and STING1 during the late phase of viral infection (By similarity).
Subcellular location: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q9HC62}. Nucleus membrane {ECO:0000250|UniProtKB:Q9HC62}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9HC62}; Nucleoplasmic side {ECO:0000250|UniProtKB:Q9HC62}. Cytoplasm {ECO:0000250|UniProtKB:Q9HC62}. Note=Shuttles between cytoplasm and nucleus. {ECO:0000250|UniProtKB:Q9HC62}.
Interaction partners:
- Nuclear pore complex protein Nup153
- Ubiquitin-like protease family profile domain-containing protein
- Sentrin/SUMO-specific protease 18
- Segment polarity protein dishevelled homolog DVL-1
- Dishevelled segment polarity protein 3
- Dishevelled segment polarity protein 2
- Small ubiquitin-related modifier 1
- Small ubiquitin-related modifier 3
- Small ubiquitin-related modifier
- Small ubiquitin-related modifier
Sequence:
MYRWLTKVLGTILRLCERPAPGARALLKRRRSSSSLFSTAVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVSSACNGTRNVAPSGEVFSNSPSCELTTSGSCSSMLKLGNKSPNGISDYPKIRVTVARDQPRRVLPSFGFTLKSEGYNRRPSGRRHSKSNPESSLPWKPQEQGVTEMISEEGGKGARRPHCTVEEGVQKDEREKYLKLLERLKEGAHGSTFPPAVSHHSSQRTQMDTLKTKGWMEEQNHGVRTTHLVPKQYRVVETRGPLCSVRSEKRYSKGKADTEKVVGLRFEKDGTRGHQLEPDLSEEVSARLRLGSGSNGLLRRKISVLEAKEKNFPSKEKDRRTEDLFELTEDMEKEISNALGHGPPDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERSKKQGYPALHALSTFFYPKLKSGGYQAVKRWTKGVNLFDQELVLVPIHRKVHWSLVVMDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNTDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
Protein: Pleckstrin homology domain-containing family A member 8 (Phosphatidylinositol-four-phosphate adapter protein 2) (A0A087X1S6)
Organism: Homo sapiens (Human)
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000256|ARBA:ARBA00004198}.
Interaction partners:
Sequence:
MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSELLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNKNSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECLWEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFAGHTNV
Protein: CUE domain-containing protein 1 (Q9NWM3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYEDSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPPTPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNAGGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ
Protein: Sodium channel regulatory subunit beta-2 (Q56A07)
Organism: Mus musculus (Mouse)
Function: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P54900}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P54900}. Cell projection, axon {ECO:0000250|UniProtKB:P54900}. Note=Clusters at the axon initial segment and node of Ranvier, the specialized neuronal subcellular domains involved in action potentials generation and propagation. {ECO:0000250|UniProtKB:P54900}.
Interaction partners:
- Sodium channel regulatory subunit beta-1
- Sodium channel regulatory subunit beta-3
- Sodium channel protein type 2 subunit alpha
- Sodium channel protein type 3 subunit alpha
- Sodium channel protein type 1 subunit alpha
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 8 subunit alpha
- Sodium channel protein type 9 subunit alpha
- Sodium channel protein type 4 subunit alpha
- Sodium channel protein type 10 subunit alpha
Sequence:
MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTAPTTLSVLNGSDTRLPCTFNSCYTVNHKQFSLNWTYQECNNCTEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLEDEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKMDGEGNAEDGTK
Protein: Hexosyltransferase (EC 2.4.1.-) (F4HR76)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}.
Interaction partners:
Sequence:
MRAKAASGKAIIVLCLASFLAGSLFMSRTLSRSYIPEEEDHHLTKHLSKHLEIQKDCDEHKRKLIESKSRDIIGEVSRTHQAVKSLERTMSTLEMELAAARTSDRSSEFWSERSAKNQSRLQKVFAVIGINTAFSSKKRRDSVRQTWMPTGEKLKKIEKEKGIVVRKFGFLFDRFVIGHSATPGGVLDKAIDEEDSEHKDFLRLKHIEGYHQLSTKTRLYFSTATAMYDAEFYVKVDDDVHVNLGMLVTTLARYQSRPRIYIGCMKSGPVLSQKGVKYHEPEFWKFGEEGNKYFRHATGQIYAISKDLATYISTNQGILHRYANEDVSLGAWMLGLEVEHVDERSMCCGTPPDCQWKAQAGNVCAASFDWSCSGICKSVDRMARVHRACAEGDTPLANFRFFV
Protein: Transmembrane inner ear expressed protein (Q8K467)
Organism: Mus musculus (Mouse)
Function: Unknown. The protein may play some role in a cellular membrane location. May reside within an internal membrane compartment and function in pathways such as those involved in protein and/or vesicle trafficking. Alternatively, the mature protein may be localized in the plasma membrane and serve as a site of interaction for other molecules through its highly charged C-terminal domain.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- LHFPL tetraspan subfamily member 5 protein
- Calcium and integrin-binding family member 2
- Transmembrane channel-like protein 1
- Transmembrane channel-like protein 2
- Protocadherin-15
Sequence:
MAGRQHGSGRLWALGGAALGACLAGVATQLVEPSTAPPKPKPPPLTKETVVFWDMRLWHVVGIFSLFVLSIIITLCCVFNCRVPRTRKEIEARYLQRKAAKMYTDKLETVPPLNELTEIPGEDKKKKKKDSVDTVAIKVEEDEKNEAKKKGEK
Protein: Adhesion G protein-coupled receptor A1 (G-protein coupled receptor 123) (Q8C4G9)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MTQWDLKTVLSLPQYPGEFLHPVVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTQHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPGADQPPYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFIALVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPESGHRHGVRPGTPPTCDALAASQLQNEHSFKAQLRAAAFTLFLFTATWTFGALAVSQGHFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWSCCPSRGDTSTTKPGAHPTLDANGDALGHTACLQDSPCPGKLRGFGHPPASHCKMTNLQAAQGHVSCLSPATPCCAKMHCEQLMEEEAAHIHMAEEDVYPHDPHLHDPHLHRCLKGRTKSHYFSRHQAAAAEREYAYHIPSSLDGSPHSSRSESPTSSLEGPMGMHTLACCAQADPFPMVSQPEGGDTSPGLYGCPPHLSPGPAHLEMLRRTQSLPFGGPSQNGLLQGDVREGLPFGTDGTGNIRTGPWKNETTV
Protein: Actin cytoskeleton-regulatory complex protein pan1 (Q10172)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton, actin patch {ECO:0000250}. Note=Cytoplasmic and cortical actin patches. {ECO:0000250}.
Interaction partners:
- Probable clathrin heavy chain
- Clathrin light chain
- Endocytosis protein end4
- Verprolin
- Actin
- Uncharacterized calcium-binding protein C800.10c
- Actin cytoskeleton-regulatory complex protein end3
- AP-2 complex subunit alpha
- Cytoskeletal protein syp1
- Protein BZZ1
Sequence:
MSYPNQMNGSMYGYGANNGVQPGFDSYGMPINQGGMNYQQQTYPYQQPYQPDGYAGNTMLPFQQSQPATQFNNGFGYASQPTGSVADYGQQQQQMYGYNGMMPQTMNNTGFMQPQQTGAIPGFAPQPTGFVQPQPTGFMSQQPASFMQPQRTGGAGFIQPQRTGAMPAYQPQMNNFMQPQKTGGFAPQATGFMQTQPFGAAPSFAPQPTGFVQPQQTGVVMPPQPTGYLQAQPTGPFASFVQPQQTASFMPAAQPLKPQKTGQIHNSKAMDTRLSFVSAADQAKFEQLFKSAVGREEAMSSEIGKAILVRSKLPTVQLSKIWRLSDTTRSGRLLFPQFVLAMYLCNLGLTGKPIPDKVPDGILNEVNAMVDAISFSLDENYAKPTQPIPQAAAQQMAAQMFGGFQQAAGIPSQITGFQPQAMMPQRTGMQPQMTGFQQPMIPQRTGMQPQMTGFQQPMMPQRTGLQPQMTGFQQPMVPQRTGMQPQMTGFQQPMMPQRTGLQPQMTGFQQPMVPQRTGMQPMMPGLQQPMAPQRTGMQPMMPQRTGMQPQMTGFQQPMAPQRTGMQPMMPQRTGMQPQMPGMQQPMAPQRTGMQPMMPQRTGMQQPMAPQRTGMQPMMPQRTGMQPQMPGMQQPMAPQRTGMQPMMPQRTGMQPQMPGMQQPMAPQRTGMQPMAPQRTGMQPMMPQRTGMQPQMPGMQQPMAPQRTGMQPMMPQRTGMQPQMPGMQQPMAPQRTGMQPMAPQRTGMQPQMTGGPMLPQRTGGMAPQPTGMPGQWGFINTPLSNLPGIEALGQQMMPNAPSGGLNNTFQQKKDIPWAISKEEKRIYDQIFDAWDKERKGTLGGNAVLEIFGQSKLTRTELEHIWNLCDHGDKGSLDRDEFAVALHLIYRKLNGNEVPAVLPPELIPPSTRNFTESLNQVKNLIKNDTSNRKPFGAENQSKLKKNSFYDNPSETTEKDATLYRHNDSDASAYVSSARRRDFKEEKIESAPPIINDIDSEIASLKKRIHEKSLVVNALEDKKLAATPANDVQNDSLIYRIKSVQDEINRLSTSNKSPEVASMNVRLEELSTRVSKMLSDINEVDHTIASLSLKLFQAEDTKNSYDQTSPEATQERNRTISSKLAEMEKQKNESKAALEQMKNYVTNIENNIRAKLLPSAANDDAWLSQNVVDESVTRVVKELPVPAPAAPQTLNPPSVSTVQQSKPIESNTHTPEVKATSESPSASSNLEDRAARIKAEAQRRMNERLAALGIKPRQKGTPSPAPVNSATSTPVAAPTAQQIQPGKQASAVSSNVPAVSASISTPPAVVPTVQHPQPTKQIPTAAVKDPSTTSTSFNTAPIPQQAPLENQFSKMSLEPPVRPAVPTSPKPQIPDSSNVHAPPPPVQPMNAMPSHNAVNARPSAPERRDSFGSVSSGSNVSSIEDETSTMPLKASQPTNPGAPSNHAPQVVPPAPMHAVAPVQPKAPGMVTNAPAPSSAPAPPAPVSQLPPAVPNVPVPSMIPSVAQQPPSSVAPATAPSSTLPPSQSSFAHVPSPAPPAPQHPSAAALSSAPADNSMPHRSSPYAPQEPVQKPQAINNIAPATNLGTSQSFSPRMGPVNNSGSPLAMNAAGQPSLAVPAVPSAPSNHFNPFAKMQPPAPSPLQPSGHDSDNWSQHGDEEEEDSEDDIRSSKDAAALAAKLFGGMAPAHPVSTPPVRPQSAAPPQMSAPTPPPPPMSVPPPPSAPPMPAGPPSAPPPPLPASSAPSVPNPGDRSALLQQIHTGTRLKKTVTTDKSKPIAGRVLDASDGNSSAWYGNLS
Protein: Peptidyl-prolyl cis-trans isomerase ppi1 (PPIase ppi1) (EC 5.2.1.8) (Cyclophilin ppi1) (Rotamase ppi1) (P87051)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Interaction partners:
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-processing protein 45
- Pre-mRNA-splicing factor spp42
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor cwf11
- Pre-mRNA-splicing factor cwf14
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cwf5
- Pre-mRNA-splicing factor cwf15
Sequence:
MANVELQTSLGKILIELYTEHAPKTCQNFYTLAKEGYYDGVIFHRVIPDFVIQGGDPTGTGRGGTSIYGDKFDDEIHSDLHHTGAGILSMANAGPNTNSSQFFITLAPTPWLDGKHTIFGRVVSGLSVCKRMGLIRTDSSDRPIEPLKIIKAVAL
Protein: S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 2.4.99.17) (Queuosine biosynthesis protein QueA) (P0A7F9)
Organism: Escherichia coli (strain K12)
Function: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Queuine tRNA-ribosyltransferase
- Epoxyqueuosine reductase
- 7-cyano-7-deazaguanine synthase
- 7-carboxy-7-deazaguanine synthase
- NADPH-dependent 7-cyano-7-deazaguanine reductase
- 6-carboxy-5,6,7,8-tetrahydropterin synthase
- Holliday junction branch migration complex subunit RuvB
- Protein translocase subunit SecF
- Protein translocase subunit SecD
- Holliday junction branch migration complex subunit RuvA
Sequence:
MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
Protein: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) (O60052)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha(cwp1) subunit is thought to participate in a stable complex with the substrate. The beta(cpp1 or cwg2) subunits bind the peptide substrate.
Interaction partners:
- Protein farnesyltransferase subunit beta
- Geranylgeranyl transferase type-1 subunit beta
- Probable CAAX prenyl protease 2
- Probable CAAX prenyl protease 1
- Dehydrodolichyl diphosphate synthase complex subunit SPAC4D7.04c-farnesyl diphosphate specific))
- Geranylgeranyl pyrophosphate synthase
- Farnesyl pyrophosphate synthase
- Dehydrodolichyl diphosphate synthase complex subunit nus1
- Decaprenyl-diphosphate synthase subunit 1
- Squalene synthase
Sequence:
MDPIDPELNEILDFTEYGPLTPIPQDDGENPLAKICYTTGYEQGMAYFRAIMAKKEYSLRALNLTGFLIMNNPAHYTVWAYRFQILNHTPSYIDNELEWLDEIAEDFQKNYQVWHHRQKILSLTKNYERELEFTKKMFEIDSKNYHVWSYRVWILQNFNDYSQELKLTNELLEKDIYNNSAWNHRFYVLFETSKVVSWSLEEELNYLKDKILFAPDNQSAWNYLCGVLDKSGPSKLDNLIANLRKNLPALHKPLLEFLAMYEPSSSEEIYQKLANEVDVPHAALWTWMSQRSNP
Protein: Brevinin-2SN4 (E7EKH7)
Organism: Sylvirana spinulosa (Fine-spined frog) (Hylarana spinulosa)
Function: Antimicrobial peptide. Active against a variety of Gram-negative and Gram-positive bacterial strains. Not active against fungi. Shows very weak hemolytic activity against human erythrocytes.
Subcellular location: Secreted {ECO:0000305|PubMed:24055160}.
Interaction partners:
Sequence:
MFTMKKPMLLLFFLGMISMSLCQDERGADEDDGGEMTEEEKRGAFGDLLKGVAKEAGLKLLNMAQCKLSGNC
Protein: Telomere length regulation protein ELG1 (Regulator of Ty1 transposition protein 110) (Telomere elongation suppressor ELG1) (Q12050)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the negative control of telomere length and in telomeric silencing through a replication-mediated pathway. May have a role in Okazaki fragment maturation. Required for S-phase progression. Component of the RFC-like ELG1-RFC complex which appears to have a role in DNA replication, replication fork re-start, recombination and repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Chromosome, telomere {ECO:0000305|PubMed:14562095}.
Interaction partners:
- Replication factor C subunit 4
- Replication factor C subunit 2
- Replication factor C subunit 3
- Replication factor C subunit 5
- Proliferating cell nuclear antigen
- Checkpoint protein RAD24
- Chromosome transmission fidelity protein 18
- ATP-dependent DNA helicase SRS2
- Flap endonuclease 1
- DNA polymerase alpha-binding protein
Sequence:
MKRHVSLSDILTGNKRKVRRQDALQITIDDENDTESGTFDARTAKHDDSSVIFLNHSVVKPIEAVSTNHKSAKEFLMTKRTKEKCDDDDDDLIVISDKSPKSETNCSKIALSQEHEDDISIISTSRIKSSLLNERASKIKNFLKHETTDTFKRLNSISKLNEIEPPLPLHQSIFPVGDKELSDRSVDIPLPFRTIPPLNHNFLPSDYESLKDKNSASCIPVRYQAPVLLGTNIKRNTTLTWPQLFKPVTLKQVLIEPKLKLRIKNWIETSFHTLEKPTLRNRLLNRINPNKQQGSGDELANFIVPDLEEDENLRPDFYRNGEANSSLSEFVPLMILHGNSIGKKTLIQTIMREIAGDDNSYQIYEVNSNMNRSKKDLLDILLDFTTTHYVKDSSKRKSDYGLVLFNDVDVLFKEHDRGYWAMISKLCEFSRRPLVLTCKDLSLVPSELIALASEQNSLFHTKKISTSTVYAFLTKYLKSLEIEVCDDWLRDVVKQNNADIRKCLMHLQFWCVDTEADLISSKNRLPVLTSTLGSSVKDISQLTDLLSINDVIGQATLNRSMVRQEIDSTTMTPEKVNTFQDQNLDDEMKLKFDYVIDYKLHLNDPNRQPLLPFELNIYQHIQEQLEARYSYVREANHRLDNEYLVNRFKKMTESTLNFLASRIPKYDHLQSARRTRNSKKISDILNQFKGIYNDETLNENAEIDLLSATTQQIKAEINPFVFEIAKSDANVKNENKQIFELHSENVSERRYKDLVYQLSQEGVLKNVWFNADPSIVVRKWEHLHSGFSKNK
Protein: ornithine decarboxylase (EC 4.1.1.17) (M4TB00)
Organism: Teladorsagia circumcincta (Brown stomach worm) (Ostertagia circumcincta)
Interaction partners:
Sequence:
MTMITQMELIGDSKVAIADGEVDAISMCQEIAHSYDQDNIDDAFMLVDLDVIFERFLLWKREMPMIEPFYAVKCNTDRVLVRTLAALGAGFDCASREEIDIVMDMGVRAEKIIYANPCKTRSFITHAKEKNVSMMTFDSVEELAKIAHLHPDAKMILRIAVSDPTARCPLNLKFGVDPVTKAPHLLVHAKELGVNVIGISFHVGSGCNDPTAFREALTHARHLTELGRGLGFDMNLVDLGGGYPGTLQQTSFEDIAAVIRSAVDEFLPPEFGVRLIAEPGRFFAAAPFTLVCNIIHATEVSAEKITKRPEDVDHRGFMYYVNDGVYGSFNCILFDHVDPVGAPLFDEIVEEYPSTIWGPTCDSLDKIEDQKMMRMMSVGEWIVYQNMGAYTCSASTTFNGFQRPNAVYVISRKNWARISTSPNV
Protein: Iroquois homeobox protein 2, a (Iroquois-class homeodomain protein IRX-2a) (Q7SZP0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MSYPQGYLYQPPGSLALYSCPLAAPRSEDLARSSSGSAFSPYPGSAAFTASANGFSSPLPYSTDPATGFPSYMGSPYDAHTTGMAGAISYHPYGSPGYPYQLNDPAYRKNATRDATATLKAWLQEHRKNPYPTKGQKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDDGDGERKDERTDKNMDNSEASAEDEGISLHVDALTDHSCSVESDGEKVTCRTGDLVCDSGAEIQDKCEATDLGEERQRGASPKPVTSSPLTGVEAPLLTHHHRENSTNKTCLDGQNQTVKPKLWSLAEIATSDPKQQNCPPGVGLLTSSAPGASPAGAVYPATSILGRPLYYTSPFYSNYTNYGNFSPLQGQGILRYNSAAEGLLHKQTGEPLIKTNPNQTEAHFRASNAESKKDPSEVFTVRSQSYLSS
Protein: Scaper protein (Q80VY7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
PDENNAVLGRNTNKQVFEGLTTGLLRAGAVVFSCLIANRPDGNSRPATPKISTQEMKNKPSQGDAFNSRVQDLISYVVNMGLIDRLHGCFLSVQGPVDENPKMATFLQHAAGFLRGMCMLCFAVTGRSSSIFDNNHQDPTGLTAALQATDLAGVLHMLYCILFHGTISDAGTSPKDSYTQNTIQVAIQSLRFFNSFAILDLSAFQSVVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLITACHNNHQNKLILEQEMSCVLLATFIQDFAQTPGHVDNQSSSLKGKFQNPGNYLELANRFPQQAWEEARQFFLKKEKK
Protein: Protein NRT1/ PTR FAMILY 1.1 (AtNPF1.1) (Nitrate transporter 1.12) (Q8LPL2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Low-affinity nitrate transporter involved in xylem-to-phloem transfer for redistributing nitrate into developing leaves. Not involved in dipeptides transport.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24006285}; Multi-pass membrane protein {ECO:0000269|PubMed:24006285}.
Interaction partners:
- High affinity nitrate transporter 2.7
- Putative inactive L-type lectin-domain containing receptor kinase III.2
Sequence:
MENPPDQTESKETLQQPITRRRTKGGLLTMPFIIANEGFEKVASYGLLQNMILYLMSDYRLGLVKGQTVLFMWVAATNFMPLVGAFLSDSYLGRFLTIVIASLSSLLGMVVLWLTAMLPQVKPSPCVATAGTNCSSATSSQLALLYTAFALISIGSGGIRPCSLAFGADQLDNKENPKNERVLESFFGWYYASSSVAVLIAFTVIVYIQDHLGWKIGFGIPAILMLLAGFLFVFASPLYVKRDVSKSLFTGLAQVVAAAYVKRNLTLPDHHDSRDCYYRLKDSELKAPSDKLRFLNKACAISNRDEDLGSDGLALNQWRLCTTDQVEKLKALVKVIPVWSTGIMMSINVSQNSFQLLQAKSMDRRLSSNSTFQIPAGSFGMFTIIALISWVVLYDRAILPLASKIRGRPVRVNVKIRMGLGLFISFLAMAVSATVEHYRRKTAISQGLANDANSTVSISAMWLVPQYVLHGLAEALTGIGQTEFFYTEFPKSMSSIAASLFGLGMAVANILASVILNAVKNSSKQGNVSWIEDNINKGHYDYYYWVLAILSFVNVIYYVVCSWSYGPTVDQVRNDKVNGMRKEEEEVIKLN
Protein: alpha-amylase (EC 3.2.1.1) (Q8N0Q7)
Organism: Drosophila kikkawai (Fruit fly)
Interaction partners:
Sequence:
MFLTKSIICLAILALASAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGFAGVQVSPVNENAVKDSRPWWERYQPISYKLVTRSGNEEQFASMTRRCNAVGVRIYVDVIFNHMAANGGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAISNYNDANQVRNCELVGLRDLNQGNSYVQEKIAEFLNHLIDLGVAGFRVDAAKHMWPADLGVIYGRLKNLNTDHGFSSGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKAFRGKDQLRYLSNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFSDTDQGPPTTDGHNIASPSFNSDNSCSGGWVCEHRWRQIYNMVAFRNAVGSDAIQNWWDNGSNQIAFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGTKNGSSCTGKTVTVGSDGRASIYLGNSEDDGVLAIHVNAKL
Protein: Ras homolog family member Ua (Ras homolog gene family, member Ua) (Rhoua protein) (Q5U3T8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Intersectin 2a.
- Intersectin-2b
- non-specific serine/threonine protein kinase
- Intersectin 1
Sequence:
MPPQGGGGEYKPVPGTVVPPVPPRRLRSRDLSSAVKSRFGTAAERRVKCVLVGDGAVGKTSLIVSYTTNGYPTEYVPTAFDNFAAVVAVDGKPVKLQLCDTAGQDEFDKLRPLCYTNADVFLLCFSVVSPSSFQNVREKWVPEIRRHCPRAPILLVGTQSDLREDVKVLIQLAQYKERPVEPQDASVCAEEVQAVSYMECSALTQKNLKEVFDTAIVASIQYSDSQQQKRLKKRTPDKMRKLSESWWKKYCCLA
Protein: Aof2 protein (A0JMQ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
ETPHSSEEEKPLSSVMLSNKKSDPGSSSSSGGNGGDRAPETLAAPQAGPAGPSGPISADVKKKERASPSGEPGGPPLPHPPGPGGIDQDSAEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKERKQVIPPPAPPIEEENDSEPEEPSGINGVEGAAFQSRLPHDRMTSQEAACFPDIINGPQHTQKVFLYIRNRTLQLWLDNPKVQLTFEATVQQLEAPYNSDAVLVHRIHSYLERHGFINFGIYKRVKPLPTKKTGKVIVIGAGVSGLAAARQLQSFGMDVTVLESRDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAGERCTSVPKEKDEMVEQEFNRLLEATSYLSHQLDFNFLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKDLLNKMVTTKEKVKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELVEMQVKLEERLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTSSGCEVIAVNTRSTTQTFIYKCDAVLCTLPLGVMKQQPPAVQFVPPLPEWKTAAIQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALMAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPAIPGASQPVPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTMPRQATANPNPQPSPSIQ