wanglab/gogpt-training-data huggingface dataset:
Protein: BolA-like protein 2 (Q9H3K6)
Organism: Homo sapiens (Human)
Function: Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts together with the monothiol glutaredoxin GLRX3.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22746225}. Nucleus {ECO:0000269|PubMed:22746225}.
Interaction partners:
- Glutaredoxin-3
- BolA-like protein 3
- Glutaredoxin-related protein 5, mitochondrial
- Anamorsin
- BolA-like protein 1
- Iron-sulfur cluster assembly enzyme ISCU
- Signal transducer and activator of transcription 4
- Ferredoxin-2, mitochondrial
- Cysteine desulfurase
- LYR motif-containing protein 4
Sequence:
MELSAEYLREKLQRDLEAEHVEVEDTTLNRCSCSFRVLVVSAKFEGKPLLQRHRLVNACLAEELPHIHAFEQKTLTPDQWARERQK
Protein: Small nuclear ribonucleoprotein G (snRNP-G) (B5DEP7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|RuleBase:RU365052}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU365052}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000256|RuleBase:RU365052}.
Interaction partners:
- Small nuclear ribonucleoprotein F
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D3
- U1 small nuclear ribonucleoprotein 70 kDa
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein-associated protein B
- Small nuclear ribonucleoprotein-associated protein N
- U1 small nuclear ribonucleoprotein A
Sequence:
MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMVVIRGNSIIMLEALERV
Protein: Enhancer of mRNA-decapping protein 3 (Q5AXT7)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm, P-body {ECO:0000256|ARBA:ARBA00004201}.
Interaction partners:
- ATP-dependent RNA helicase DHH1
- Decapping enzyme Dcp2, putative
- Decapping enzyme Dcp1, putative
- Topisomerase II associated protein
- G2/M phase checkpoint control protein Sum2, putative
- 5'-3' exoribonuclease 1
- U6 snRNA-associated Sm-like protein LSm4
- U6 snRNA-associated Sm-like protein LSm2
- ATP-dependent
- U6 snRNA-associated Sm-like protein LSm3
Sequence:
MASEFIGYNVLVTLRAPPDATVQGVVADVIGQRLMLRDVTLSWIGYRLPTYSIEAPDIADLSLGPSDRPSAQASHVLQEKQSLGTPYAVQQPFVDPAILSFSKPSSEAHASVQPQAGFTESSGARQLPTSQDTSQVTSQATPATLAEPFSNLELNVGNRSTPQAEELQGPLSRVVEESPVSASRFGTTRGRRGGKQKDPSVYNEHDGALNTNPKSKGWRQTAFVEPSNPSLLDSPQSYKETGTLNGKRRKKKSRGYPAQVSGWATEEATDIQEMGDFDFASNLSKFDKRRVFEEIRNDDTTADEERLVSFNRRVPKPGTNGGRNLHWSENVLDDSLEESDNEATNHEPSDAKLSSGTISGRDASKLSTRGRGSRKGSAIFGQPLIPTQLNTIGRSQLSNSRTKSSSPLPTKTHVSASPVTGISASSATLRLATTNRSCPAVSPLQILEVEQLAIGEVGLTEDMITENAGRSIAEAAVGLLSSDAAAPTILALVGNHRTGARVISSARHLRNRGHRVTVCMLGVEQEVELLESCRKQVDIFKKIGGRFLKWEELSSRLSTSEFAPDLVLDALLGIHLPFNDLRTDDQATAFEMISWINRSGLDTLSVDVPSGLSATTGEVTVVESGQLRVNSKSIVSLGAPKTGLVNALLAGEGASWNLTVADIGIPQIAWRKFGTRRRHGIDFGNRWVVSLRYQPSVV
Protein: Uncharacterized metal-dependent hydrolase YcfH (EC 3.1.-.-) (P0AFQ7)
Organism: Escherichia coli (strain K12)
Function: Has D-tyrosyl-tRNA deacylase activity in vitro.
Interaction partners:
- Endolytic murein transglycosylase
- DNA polymerase III subunit delta'
- Thymidylate kinase
- Aminodeoxychorismate lyase
- Acyl carrier protein
Sequence:
MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTLPGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYTPETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTEDRETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKENQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR
Protein: HTH-type transcriptional regulatory protein TyrR (P07604)
Organism: Escherichia coli (strain K12)
Function: Dual transcriptional regulator of the TyrR regulon, which includes a number of genes coding for proteins involved in the biosynthesis or transport of the three aromatic amino acids, phenylalanine, tyrosine and tryptophan. These three aromatic amino acids act as effectors which bind to the TyrR protein to form an active regulatory protein. Modulates the expression of at least eight unlinked transcription units, including aroF, aroG, aroLM, aroP, mtr, tyrA, tyrB and tyrP. In most cases TyrR acts as a repressor, but positive effects have been observed on the tyrP gene, which is repressed in the presence of tyrosine and activated at high phenylalanine concentrations. Is also involved in activation, but not repression, of mtr expression in association with phenylalanine or tyrosine. Acts by binding specifically to TyrR boxes in the promoter region of the target genes.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- T-protein
- Tyrosine-specific transport system
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
- Bifunctional chorismate mutase/prephenate dehydratase
- Aromatic amino acid transport protein AroP
- Trp operon repressor
- RNA polymerase sigma-54 factor
- Aromatic-amino-acid aminotransferase
- Shikimate kinase 2
Sequence:
MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFAELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKVDMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLMEITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVEQAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVRVICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATVAVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQKKNEE
Protein: Probable inactive beta-glucosidase 25 (AtBGLU25) (O82772)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- WPP domain-interacting protein 3
- Glycosyl hydrolase family protein
- Glycosyl hydrolase family protein
- Beta-glucosidase 11
- Beta-glucosidase 8
Sequence:
MALKAILFLGLFLVVIVSPITVYGGAVCPASSTFGRGSFPDGFLFGATTSAFQHEGAAEEGGRGSSIWDSFTLKQHSESNNNLDGRLGVDFYHHYKEDVQLLKKLNMDAFRFSISWSRIFPHGKKDKGVSETGVKFYNDLINELIANGVTPLVTLFQWDVPQALEDEYGGFLSDRILEDFRDFAQFAFNKYGDRVKHWVTINEPYEFSRGGYETGEKAPGRCSKYVNEKCVAGKSGHEVYTVSHNLLLAHAEAVEEFRKCGKCTGGKIGIVQSPMWFEPYDKKSTSSPSEEIVKRAMDFTLGWHMEPITHGDYPQAMKDVVGSRLPSFTPEQKEKLKGSYDFVGINYFTSTFVAHTDNVNPEKPSWEADSRLQLHSNNVDGFKIGSQPATAKYPVCADGLRKVLKYIKENYNDPEIIVTGNGYKETLEEKDVLPDALSDSNRKYYHMRHLMALHGAVCEDKVNVKGYFVSSLMDGLEWEDGYKTRSGLYYVDYGHNMGRHEKQSAKWLSKLLEKVPDTIQSKVDSDSRKEL
Protein: H2B.U histone 2 (Histone H2B type 3-A) (Q9D2U9)
Organism: Mus musculus (Mouse)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000269|PubMed:15197225}. Chromosome {ECO:0000269|PubMed:15197225}.
Interaction partners:
- Histone H4
- Histone H3.1
- Histone H3.3
- Histone H3.2
- Plasminogen
- Histone H2A type 1-K
- Histone H2AX
- Histone H3-like centromeric protein A
- Breast cancer type 1 susceptibility protein homolog
- Histone deacetylase 1
Sequence:
MPEPSRSTPAPKKGSKKAITKAQKKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
Protein: Serine/threonine-protein phosphatase 4 regulatory subunit 1 (Q8TF05)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3.
Interaction partners:
- Serine/threonine-protein phosphatase 4 catalytic subunit
- Serine/threonine-protein phosphatase 4 regulatory subunit 2
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Serine/threonine-protein phosphatase 4 regulatory subunit 3A
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
- Serine/threonine-protein phosphatase 2A activator
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Sequence:
MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
Protein: E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Liver regeneration-related protein LRRG126) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Q7TPK1)
Organism: Rattus norvegicus (Rat)
Function: Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication. In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD-type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) and unmethylated at 'Arg-2' (H3R2me0), respectively, and recruits chromatin proteins. Enriched in pericentric heterochromatin where it recruits different chromatin modifiers required for this chromatin replication. Also localizes to euchromatic regions where it negatively regulates transcription possibly by impacting DNA methylation and histone modifications. Has E3 ubiquitin-protein ligase activity by mediating the ubiquitination of target proteins such as histone H3 and PML. It is still unclear how E3 ubiquitin-protein ligase activity is related to its role in chromatin in vivo. Plays a role in DNA repair by cooperating with UHRF1 to ensure recruitment of FANCD2 to interstrand crosslinks (ICLs) leading to FANCD2 activation (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8VDF2, ECO:0000255|PROSITE-ProRule:PRU00358}. Note=Associated, through the YDG domain (also called SRA domain), with replicating DNA from early to late S phase, including at replicating pericentric heterochromatin (By similarity). Also localizes to euchromatic regions. In non-S-phase cells, homogenously distributed through the nucleus (By similarity). {ECO:0000250|UniProtKB:Q8VDF2}.
Interaction partners:
- DNA
- [histone H3]-lysine
- Ubiquitin carboxyl-terminal hydrolase 7
- Histone deacetylase 1
- DNA
- Histone deacetylase 1
- DNA
- DNA ligase 1
- Histone acetyltransferase KAT5
- DNA ligase
Sequence:
MWIQVRTMDGKETHTVNSLSRLTKVQELRKKIEELFHVEPQLQRLFYRGKQMEDGHTLFDYDVRLNDTIQLLVRQSLALPLSTKERDSELSDSDSGYGVGHSESDKSSTHGEGTADGDDKTVWEDTDLGLYKVNEYVDVRDNIFGAWFEAQVVQVQKKALSEEEPCSSSAIMAPEDDIMYHIKYDDYPEHGVDIVKAKNVRARARTVIPWEDLEVGQVVMANYNVDYPRKRGFWYDVEICRKRQTRTARELYGNVMLLNDSQLNNCRIIFVDEVLKIELPNERSPLIGSPSRRKSGPSCQYCKDDENKPCRKCACHICGGREAPEKQVLCDECDMAFHLYCLQPPLTCVPPEPEWYCPSCRTDSSEVVQAGEKLKKSKKKAKMASATSSSRRDWGKGMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNFFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPEKGKSGFIVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANKEKNRKRPAKALEQGPSSSKIGKSKRKSTGPATTSPRVSKKSKLEPYTLPLQQANLIKEDKGNAKLWDDVLSSLQDGPYQIFLSKVKEAFQCICCQELVFRPVTTVCQHNVCKDCLDRSFRAQVFSCPACRYDLDHSSPTRVNQPLQTILNQLFPGYGSGR
Protein: Bi-functional coumaroyl CoA and feruloyl CoA ortho-hydroxylase F6H2-1-1 (IbF6H2-1-1) (EC 1.14.11.61) (EC 1.14.11.62) (2-oxoglutarate-dependent dioxygenase F6H2-1-1) (2OGD F6H2-1-1) (G9M9M4)
Organism: Ipomoea batatas (Sweet potato) (Convolvulus batatas)
Function: 2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD) involved in scopoletin and umbelliferone biosynthesis. Converts feruloyl CoA into 6'-hydroxyferuloyl CoA, and p-coumaroyl CoA into 2,4-dihydroxycinnamoyl-CoA, but has no activity with caffeoyl-CoA.
Interaction partners:
Sequence:
MPSTTLSTVLSDINEFVVKQGHGVKGLSELGLQTLPNQYVHPPEERLSSMDVVSDDSIPVIDVSNWEDPKVAKLICDAAEKRGFFQIVNHGIPLEMLEKAKAATYRFFREPAEEKKKYSKENCPTSHVRYSTSFLPQIEKALEWKDHLSMFYVSDEEAAQYWPPSCRDDALEYLKSCEMVSRKLLEALMQGLNVNEIDDAKESLLMGSRRININYYPKCPNPDLTVGVGRHSDISTLTLLLQDDIGGLYVRKLEHEAWSHVPPVKGALVINIGDALQIMSNGRYKSIEHRVLANETNDRISVPVFVNPKPNDIVGPLPEVLASGEKPVYKPVLYSDYAKHFYRKAHNGKDTIAFARIE
Protein: DNA repair protein rhp42 (P87235)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active genes and in global genome repair (GGR) which removes damage in untranscribed DNA. Involved in the repair of short-patch mismatch during meiosis.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DNA repair protein rhp41
- DNA repair protein rhp7
- General transcription and DNA repair factor IIH subunit tfb1
- UV excision repair protein rhp23
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription and DNA repair factor IIH helicase subunit XPD
- Uncharacterized MFS-type transporter C16A3.17c
- Cell division control protein 31
- DNA repair protein rhp26
- DNA repair protein rad14
Sequence:
MPPKRKASKNSVRGRKRRTRTNNLPLNPEVKEETVVSSTHRQTRSQSKKPSLSSSAEPPSESLDDNISALNSLQRSASSSEKGSDEDNEKLGSSEDDEFDDDFDTWEQVDLSPNKQEDKKDLHIVTQHITPQLTKESKKGSSSAMDKSIRLSIHIMHFTCLLYHGSVRNRWLMNSLLLDGLRDLLVEKQPSVVEAWVCSSQTHEDLLKLLNGLRMWWNKSFKIESHGLRKLGYRTLKQGFDIGFSPEIFHNFHEYQASLLSLKGSRDLAAQGFTALCRSLNLKARLIFSLQPLTFSTASYDDWSPHILPEETSTSIDDDLRYPIFWTEIYDQSEKKWIAVDAVVLNGVYTNDMTWFEPKGAYAESKHLRMGIVAAYDNDLYAKDVTLRYTDYQSSRLKKIRHVSFADKYFDFYKAIFGQLAKRNKDAEDIYEEKELESKVPIREPKSFADFKNHPEFVLIRHLRREEALLPNAKPVKTATFGNGKKATSEEVYLRKDVVICKTPENYHKEGRVIKEGEQPRKMVKARAVTISRKREHEFRVAETNEPVLQGLYSSDQTELYVPPPIKDGIIPKNGYGNMDCFVESMIPKGAAHLPYRGIAKIAKKLNIDYADAVTGFEFRKHRAIPVTTGIIVPEESAQMVYEEFLECEKIRIEKQQMKERKIIYGQWKHLLNALRIRKRIEEQYA
Protein: DNA-directed RNA polymerase II protein (Q8H1E1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Beclin-1-like protein
- Serine/threonine-protein kinase VPS15
- Phosphatidylinositol 3-kinase VPS34
Sequence:
MTKRSSNCAICDNTNRPCICTACVNHRLIEYNTLLKSLKTRRDSLLSRFNELLESKGKADDQKNWRLIQNEKISKLKKKLKSNKELVTQGKVKIERGSSDLKVKYGVLDSARSTLEKTRVEQVEKYFPNLICTQSLGHMAISSERLHKQSVVVKQICKLFPLRRVSFDGESQNGSVRQYDVICNSRLPSGLDPHSIPSEELAVSLGYMVQLLNLVVHNLAAPALHSSGFAGSCSRIWQRDSYWDGRTSTRSNEYPLFIPRRNYCSTSVENSWTDKNSSNFGVASMESDRKEPRLDSPGSNSFKYSSASPHSIESHRDLQKGIALLKKSVACLTAYCYNSLCLEVPPEASTFEAFAKLLATLSSSKEVRSVFSLKMASSRSGKQAQQLNKSIWNAHSVISSSLLESAHLPRNTSYNQDPNSPASYLSATELSTRKNNDMNGWDLVEHPKYPPPPSQSEDVEHWTRAMFIDAKKK
Protein: Hydroxycarboxylic acid receptor 2 (A0A4Y1JWQ0)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP
Protein: NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial (EC 7.1.1.2) (A0A1D8PU51)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion {ECO:0000255}.
Interaction partners:
- 4Fe-4S ferredoxin-type domain-containing protein
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- Zinc finger CHCC-type domain-containing protein
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase iron-sulfur protein 4
- NADH-ubiquinone oxidoreductase chain 4
- Nuc2p
- NADH-ubiquinone oxidoreductase chain 3
- Uncharacterized protein
- Cytochrome b-c1 complex catalytic subunit, mitochondrial
Sequence:
MNSIKSHILRSSKRYISASSKRLAEVEVTVDGRKVSIEAGSSIIQAAELAGVTIPRYCYHDKLAIAGNCRMCLVDVERMPKLIASCAMPVQNGMVVHTDSERIKKAREGVTEMLLENHPLDCPVCDQGGECDLQEQSQRYGSDRGRFHEVVGKRAVENKAIGPLVKTSMNRCIHCTRCVRFMNDVAGAPEFGTAGRGNDMQIGTYIERNINSEMSGNIIDLCPVGALTSKPYAFRARPWELKRTETIDVLDAVGSNIRVDTRGIEVMRVLPRLNDDVNEEWISDKTRFACDGLKTQRLTTPLIRNGDKFETATWDEALSTIAAAYSKINPQNGELKAIAGALVDAESLVSLKDLVNKLGSENVTTDVKQSVNAHGFDIRSNYIFNSTIDGIEDADQILLVGTNPRFEAAVLNTRIRKVWLRSNLEISSVGQDFNSTFDVTNLGEDAKALESALQGSVGEKLGQAKKPLIIVGSGVAESKDSEAIYKLVGEFASKHENFNSGEWNGVNLLHREASRVAALDLGFNTLVEDSTKAKFIYLLGADEITNKDIPKDAFVVYQGHHGDLGASFADVILPGSAYTEKSGTYVNTEGRVQATRAATNPPGVAREDWKIIRALSEYLNAKLPYDDIYSVRLRLGEIAPHLVRHDVIEPVSQEIAKIGFNDLVNKNKSATIFEEPLKNPIDNFYFTDVISRSSPTMAKCISTFGAKIEKVKDEKPDINF
Protein: FeoA family protein (B7J757)
Organism: Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))
Interaction partners:
- Ferrous iron transport protein B
Sequence:
MNSSIISPPEPLFIGDLRPGDHARVLEITGGKIMQQRLGMLGIRRDTLVRVVHGPGKRGAVLQVGGARVALGWGVIQRVRVAIIPTESPHTGEKT
Protein: Mucin related 11Da (Q8IR74)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform A
- Femcoat
- Uncharacterized protein
- Kazal-like domain-containing protein
- MIP13722p
- Uncharacterized protein, isoform B
- Chorion protein S16
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MLRAFAFTVLLTALTLSQGHGDDYLRFPDPGNIPRYNQRPCGPRVCGKSGHCYRSFESICDFNDYNLKMIFSGQELFELTEPIYCQPSPPRTKLVDVGYYFNHRSLLVAQSQPSAYSSPIPRPSFTQNPKNIEHYDAYPSSDSYGPVQDYELPYPVWAFKRPQAPPRSPPVSYRPPYWYYPTRRPEITKPCYGRTTTATKAPVTTTTTTEASTTTTTIEPSTSTNAAFTTTTSTEASTTTTTEGTTTSTEQTTTTKTTSPSTSTEILTTTTELTTSTEPARTTESTTTTIADSASTITEQSNTTEPTTTAEPTTTTEPTTTTEPTTTTENTTTTEPTTTTEPTTTTEPTTTTENTTTTEPTTTTEPTTTTEPTTTTESTTTTERVTNTDLTTTTTLLTTTKSQTSTDPSTTSSTTEPSTTTNRSSSSTTTTTVTTEPSTTTTVSSTTTTKDPTTTESSTTTTTVPTTLAESSTVTTTLISKTTTSEPSTTSSTDSSTTTLTTDAPSTTTLSTETSTTINPAAVKPVTVEVTNEDGQIVDFELAAMAVNPETGEPNCAEVTNVLITTGSRIVFQFSGCIVARVASRTIIEPTTTSSTTVATTTQNTPHYQWYGGSAAYAQSHFLYTY
Protein: Extracellular sulfatase Sulf-1 (mSulf-1) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form] (Q8K007)
Organism: Mus musculus (Mouse)
Function: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation (By similarity).
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8VI60}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q8VI60}. Cell surface {ECO:0000269|PubMed:12368295}.; SUBCELLULAR LOCATION: [Extracellular sulfatase Sulf-2 secreted form]: Secreted {ECO:0000269|PubMed:12368295}.
Interaction partners:
- Heparan sulfate 2-O-sulfotransferase 1
Sequence:
MKYSLWALLLAVLGTQLLGSLCSTVRSQRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEQGGATFTNAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPIMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNVLQRKRLQTLMSVDDSVERLYNMLVESGELDNTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSIEPGSIVPQIVLNIDLAPTILDIAGLDSPSDVDGKSVLKLLDLEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESGKNIQQSNHLPKYERVKELCQQARYQTACEQPGQNWQCIEDTSGKLRIHKCKGPSDLLTVRQNARNLYSRGLHDKDKECHCRDSGYRSSRSQRKNQRQFLRNKGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEELQVLPPRSIAKRHDEGHQGFIGHQAAAGDIRNEMLADSNNAVGLPATVRVTHKCFILPNDTIHCERELYQSARAWKDHKAYIDKEIEVLQDKIKNLREVRGHLKKRKPEECGCGDQSYYNKEKGVKRQEKLKSHLHPFKEAAAQEVDSKLQLFKEHRRRKKERKEKKRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERSILNQLHIQLMELRSCQGYKQCNPRPKSLDIGAKEGGNYDPHRGQLWDGWEG
Protein: Podocalyxin-like protein 2 (Endoglycan) (Q9NZ53)
Organism: Homo sapiens (Human)
Function: Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Transmembrane and coiled-coil domains protein 1
- Cilia- and flagella-associated protein 100
- Krueppel-like factor 15
- Plexin-D1
- Protein-tyrosine sulfotransferase 2
- Protein-tyrosine sulfotransferase 1
- Plexin-A1
- L-selectin
Sequence:
MGRLLRAARLPPLLSPLLLLLVGGAFLGACVAGSDEPGPEGLTSTSLLDLLLPTGLEPLDSEEPSETMGLGAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLDLGPTADYVFPDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQSRIPWDSTQVICKDWSNLAGKNYIILNMTENIDCEVFRQHRGPQLLALVEEVLPRHGSGHHGAWHISLSKPSEKEQHLLMTLVGEQGVVPTQDVLSMLGDIRRSLEEIGIQNYSTTSSCQARASQVRSDYGTLFVVLVVIGAICIIIIALGLLYNCWQRRLPKLKHVSHGEELRFVENGCHDNPTLDVASDSQSEMQEKHPSLNGGGALNGPGSWGALMGGKRDPEDSDVFEEDTHL
Protein: LD12946p (Membrane steroid binding protein, isoform A) (Membrane steroid binding protein, isoform B) (Membrane steroid binding protein, isoform C) (Steroid membrane binding protein) (Q9VXM4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDSKVGADPSSAYDKEIGNNLNNDDSSFLGNIIREILYSPMNLALLAIICFLVYKIVRDRTEVPSVGVAKPSEPELPKIRRDFTVKELRQYDGTQPDGRVLVAVNGSVYDVSKGRRFYGPGGPYATFAGRDASRNLATFSVVSIDKDEYDDLSDLSAVEMDSVREWEMQFKEKYELVGKLLRKGEEPTNYDDDEDEENVNNDEQERKNLPKSKTETDDTKQEKESHILQSNVTNKNNAQDQATPSTDC
Protein: tRNA-specific adenosine deaminase subunit TAD2 (EC 3.5.4.33) (tRNA-specific adenosine-34 deaminase subunit TAD2) (P47058)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Deaminates adenosine-34 to inosine in many tRNAs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- tRNA-specific adenosine deaminase subunit TAD3
- tRNA-specific adenosine deaminase 1
- Cytidine deaminase
- Bifunctional protein RIB2
- Mitochondrial FAD-linked sulfhydryl oxidase ERV1
- Deoxycytidylate deaminase
- Cytosine deaminase
- tRNA
- Adenine deaminase
- tRNA
Sequence:
MQHIKHMRTAVRLARYALDHDETPVACIFVHTPTGQVMAYGMNDTNKSLTGVAHAEFMGIDQIKAMLGSRGVVDVFKDITLYVTVEPCIMCASALKQLDIGKVVFGCGNERFGGNGTVLSVNHDTCTLVPKNNSAAGYESIPGILRKEAIMLLRYFYVRQNERAPKPRSKSDRVLDKNTFPPMEWSKYLNEEAFIETFGDDYRTCFANKVDLSSNSVDWDLIDSHQDNIIQELEEQCKMFKFNVHKKSKV