wanglab/gogpt-training-data huggingface dataset:
Protein: Glycophorin-B (PAS-3) (SS-active sialoglycoprotein) (Sialoglycoprotein delta) (CD antigen CD235b) (P06028)
Organism: Homo sapiens (Human)
Function: This protein is a minor sialoglycoprotein in erythrocyte membranes.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Glycophorin-A
- Ammonium transporter Rh type A
- Band 3 anion transport protein
- Leukocyte surface antigen CD47
- Blood group Rh
- Rh blood group D antigen
- Protein 4.2
- Glycophorin-C
- Ankyrin-1
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
Sequence:
MYGKIIFVLLLSEIVSISALSTTEVAMHTSTSSSVTKSYISSQTNGETGQLVHRFTVPAPVVIILIILCVMAGIIGTILLISYSIRRLIKA
Protein: Deoxymugineic acid synthase 1 (OsDMAS1) (EC 1.1.1.285) (Q10PE7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the reduction of a 3''-keto intermediate during the biosynthesis of 2'-deoxymugineic acid (DMA) from L-Met. Involved in the formation of phytosiderophores (MAs) belonging to the mugineic acid family and required to acquire iron.
Interaction partners:
- Bifunctional dihydrofolate reductase-thymidylate synthase
- thymidylate synthase
- Putative bifunctional dihydrofolate reductase-thymidylate synthase
- glucuronokinase
- Probable aldo-keto reductase 1
- Probable aldo-keto reductase 2
- Probable voltage-gated potassium channel subunit beta
- Os12g0482700 protein
Sequence:
MSDGGAGAKGAGFGMPRVGMGTAVQGPRPEPIRRAVLKAIEAGYRHFDTAAHYETEAPIGEAAAEAVRSGAIASRADLFITSKLWCSDAHRDRVLPALRQTLWNLQMEYVDLYLVHWPVSMKPGRYKAPFTADDFVPFDMRAVWEAMEECHRLGLAKAIGVCNFSCKKLDTLLSFATIPPAVNQVEVNPVWQQRKLRELCREKGVQICAYSPLGASGTHWGSDSVMASAVLRDIAQSKGKTVAQVCLRWVYEQGDCLIVKSFDEARMRENLDIVGWELTEEERQRIAGIPQRKINRALRFVSDHGPYKSLDDLWDGEI
Protein: Homeobox protein vent1 (Xvent-1) (Q91926)
Organism: Xenopus laevis (African clawed frog)
Function: Transcriptional repressor. Cooperates with vent2 in a ventral signaling pathway downstream of bmp4, which antagonizes the Spemann organizer and dorsal mesoderm formation, and leads to ventral mesoderm formation. Acts downstream of bmp4 to repress transcription of foxa4-B/XFD-1'. Binds to DNA with preference for the target sequence 5'-CTATT[T/C]G-3'. Also binds 5'-TGCATTTTG-3' at a lower frequency, and occasionally 5'-TTGATC-3'. Binds to the homeobox 2 (HBX2) repressor element in the promoter of the myf5 gene and represses myf5 transcription in the ventral domain.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MVQQGFSIDLILARSKEEATDGKDSMSSRPHIPCAPQPLPPTKYAKEMPRKKDGQDVQEHTTSFQCSLGEQVINRPSANPSLAAMHRSSGSSDEFSPPGSEDDSTESSGRSSQENDTEQREKSPKSDLQRRLRTAFTPQQISKLEQAFNKQRYLGAPERKKLATSLQLSEIQVKTWFQNRRMKLKRQIQDKQHSLVPPPVCYPQTFPYYPGGFPVPLNSGSFYQPRALPFQAPQHSYIPQPLHHHVRMSSHQEQYPPLFGAQYM
Protein: Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1) (O77760)
Organism: Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
Function: Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P35610}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P35610}.
Interaction partners:
Sequence:
MVGEEKMSLRNRLSKSRENPEEDEDQRKPAKESLEAPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQRWATGYSKSSHPLINSLFHGFLFMVFQIGILGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMQFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVMMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
Protein: Killer cell immunoglobulin-like receptor 2DL2 (CD158 antigen-like family member B1) (Natural killer-associated transcript 6) (NKAT-6) (p58 natural killer cell receptor clone CL-43) (p58 NK receptor CL-43) (CD antigen CD158b1) (P43627)
Organism: Homo sapiens (Human)
Function: Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
Sequence:
MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVIGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYAELPNAESRSKVVSCP
Protein: Uridine/cytidine kinase UKL1, chloroplastic (EC 2.7.1.48) (AtUK) (Uridine kinase-like protein 1) (Uridine/cytidine kinase 1) (Q9FKS0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the pyrimidine salvage pathway (Probable). Phosphorylates uridine to uridine monophosphate (UMP). Phosphorylates cytidine to cytidine monophosphate (CMP). Does not possess uracil phosphoribosyltransferase (UPRTase) activity that catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:21828290}. Cytoplasm {ECO:0000269|PubMed:17143579}. Note=Aggregates in granular precipitates restricted to the cytoplasm, when expressed in transfected cells. {ECO:0000269|PubMed:17143579}.
Interaction partners:
- Uridine nucleosidase 1
- Uridine 5'-monophosphate synthase
- Uracil phosphoribosyltransferase, chloroplastic
- UMP kinase
- dCMP deaminase
- Alkaline-phosphatase-like family protein
- Dihydroorotate dehydrogenase
- Dihydropyrimidine dehydrogenase
- Cytidine deaminase 5
- Cytidine deaminase 6
Sequence:
MPEDSSSLDYAMEKASGPHFSGLRFDGLLSSSPPNSSVVSSLRSAVSSSSPSSSDPEAPKQPFIIGVSGGTASGKTTVCDMIIQQLHDHRVVLVNQDSFYRGLTSEELQRVQEYNFDHPDAFDTEQLLHCAETLKSGQPYQVPIYDFKTHQRRSDTFRQVNASDVIILEGILVFHDSRVRNLMNMKIFVDTDADVRLARRIRRDTVERGRDVNSVLEQYAKFVKPAFDDFVLPSKKYADVIIPRGGDNHVAVDLITQHIHTKLGQHDLCKIYPNVYVIQSTFQIRGMHTLIREKDISKHDFVFYSDRLIRLVVEHGLGHLPFTEKQVVTPTGAVYTGVDFCKKLCGVSIIRSGESMENALRACCKGIKIGKILIHRDGDNGKQLIYEKLPHDISERHVLLLDPVLATGNSANQAIELLIQKGVPEAHIIFLNLISAPEGIHCVCKRFPALKIVTSEIDQCLNQEFRVIPGLGEFGDRYFGTDEEDQ
Protein: Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Q9JHY7)
Organism: Rattus norvegicus (Rat)
Function: Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules (By similarity). Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis (By similarity). The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (By similarity). May counteract a default induction of apoptosis in G2/M phase (By similarity). The acetylated form represses STAT3 transactivation of target gene promoters (By similarity). May play a role in neoplasia. Inhibitor of CASP3 and CASP7 (By similarity). Essential for the maintenance of mitochondrial integrity and function (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O15392}. Nucleus {ECO:0000250|UniProtKB:O15392}. Chromosome {ECO:0000250|UniProtKB:O15392}. Chromosome, centromere {ECO:0000250|UniProtKB:O15392}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:O15392}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:O15392}. Midbody {ECO:0000250|UniProtKB:O15392}. Note=Localizes at the centromeres from prophase to metaphase, at the spindle midzone during anaphase and a the midbody during telophase and cytokinesis. Accumulates in the nucleus upon treatment with leptomycin B (LMB), a XPO1/CRM1 nuclear export inhibitor (By similarity). Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody. Colocalizes with AURKB at mitotic chromosomes (By similarity). {ECO:0000250|UniProtKB:E3SCZ8, ECO:0000250|UniProtKB:O15392}.
Interaction partners:
- Inner centromere protein
- Borealin
- Aurora kinase B
- G2/mitotic-specific cyclin-B1
- Aurora kinase A
- Cyclin-dependent kinase 1
- Cell division cycle protein 20 homolog
- Ubiquitin-conjugating enzyme E2 C
- Diablo IAP-binding mitochondrial protein
- Serine/threonine-protein kinase PLK1
Sequence:
MGATALPPIWQMYLKDHRIYTFKNWPFLEDCSCTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEHRKHSPGCAFLTVKKQVEELTVSEFLKLDKQRAKNKIAKETNNKQKEFEETRRTVRQSIEQLAALR
Protein: Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9) (A1A5Z0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Phosphotransferase
- Hexokinase 1.
- Hexokinase 2.
- Hexokinase-2
- Phosphoglucomutase 1
- Glucose-6-phosphate 1-dehydrogenase
- ADP-dependent glucokinase
- Aldose 1-epimerase
- ADP-dependent glucokinase
- Glucose-6-phosphate isomerase
Sequence:
MESLYRQGVWMAEALQQNSRSLEDLWLVASHMGDPKAAVLLVFPVVFYIHRRTGIAVLWVAALSEWLNLVFKWILFGERPYWWIGQSGLFSEKPPEVQQFQSTCESGPGSPSGHAMVTSAVWWVIISSLASFSQAYTGSKILSAVLYLLYAVFLGCVGLSRIFILAHFPHQVVAGLLTGVLLGVFLKRSVPERRPLLFFFRFSMALLGAALIFHAVLEKTGIDLSWSISLAKRWCSRSEWVRMDTAPFSSLNRDAGVLLGLGLAQYWKPGGWTLPRAPRTLCLALSSLALHYISRFPLPTVPPLLFYSLFFLKYSIVPQVVMVLVPGFVHLLTAKPKRE
Protein: Probable fructokinase-5 (EC 2.7.1.4) (O82616)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play an important role in maintaining the flux of carbon towards starch formation.
Interaction partners:
- Glucose-6-phosphate isomerase, cytosolic
- Glucose-6-phosphate isomerase 1, chloroplastic
- Sorbitol dehydrogenase
- Hexokinase-4
- Hexokinase-3
- Hexokinase-2
- Hexokinase-1
- Hexokinase-like 1 protein
- Probable hexokinase-like 2 protein
- alpha-D-xyloside xylohydrolase
Sequence:
MANTPLIVSFGEMLIDFVPDTSGVSLAESTGFLKAPGGAPANVACAITKLGGKSAFIGKFGDDEFGHMLVNILKKNGVNSEGVCFDTNARTALAFVTLKKDGEREFMFYRNPSADMLLKESELNKDLIKKAKIFHYGSISLISEPCRTAHMAAMKTAKDAGVLLSYDPNVRLPLWPSTEAAIEGIKSIWNEADIIKVSDDEVTFLTRGDAEKDDVVLSLMHDKLKLLIVTDGEKGCRYYTKKFKGRVPGYAVKAVDTTGAGDSFVGAFLVSLGKDGSILDDEGKLKEALAFANACGAVCTTQKGAIPALPTPADAQKLMKSKSK
Protein: poly(A)-specific ribonuclease (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase) (Glucose-repressible alcohol dehydrogenase transcriptional effector) (Q8MTZ5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRNKDKYDSANRRQQIFLSQEDIAAGKKTNWSGLEITGGYHTLNPEKYHINSTIHLFTGCVRNISPSLWEFEHLTALYLNDNQLLRLPADVGMLTSLRTLDLSSNKLRSLPAELGELIQLRELLLNNNFLRVLPYEIGKLFHLVILGLMGNPLQKEFMNIYNEPNGTQKLLTYMLDNLSFTVNPPPQRPWLPLAKPNKTRPACIFTVMCYNVLCDKYATRQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMANAEGSDNMLNRVMPKDNIGLAALLKVKENAWEPMSEVTQISQPLLVCTAHIHWDPEFCDVKLIQTMMLSNELKTIIDEASHSFRPGHKNDSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMDHLDFKDMGYKSCLQRLLSNDTNEFTHSFKLASAYNEDIMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVELELMHTASQQAPPNGLINRR
Protein: Protein HEATR9 (HEAT repeat-containing protein 9) (Q5QNV8)
Organism: Mus musculus (Mouse)
Interaction partners:
- Secretion-regulating guanine nucleotide exchange factor
Sequence:
MESQEKQADFFQIPKSMDYRNRNKKFRKAMAPVHLPLSCYKVPKEAFPPSPECWRVHPSRPNATPCLHLDKKPDLFTHWRTLNEQRKERESKSLFWKRRNFPRYFKDSAQMPNLHVSISKLTLKPKEGPGLLDPTKDPLKWQRLKELTNGLNSPQEDEQCYAAYALGHLGISNKFVMEALWQVAQTGSTKVKNEAYKSLASLGCLDKSVIKAFIKQLMEHKESQRLETLVGLRVALNSWAAMPKNKKPEVPYEEKLVLLLQNLIYKPLNEESLEAALCLGFLRPSNSIVQQFLLQCLSKGSMSQRMKALRMLVKMMNVHSAAVTRAILEQLHSNVIDDRLEATQMLKTVGLEKIQAQGLVKLTFDLLKRKMYSEPFQVIRQAVSETVDVLKMKPLIMKLMEAQLMSPDVSDRQEAIISLGALGIRNEKVFHLLLDMLDAEETKSVKKSIQETLLVWASRNPWIQNKLTNKVFFVYDIPKAVKTEHTRFRKKPESPDDLCITDFRRAKLNPLFITKAYNKLGEKLEAPAFSFYFSKPKKQRPQATGPWEPKIREQLRNMVLPQNRFLFWL
Protein: Gastrin [Cleaved into: Gastrin-71 (G71); Big gastrin (Gastrin-34) (G34); Gastrin] (P48757)
Organism: Mus musculus (Mouse)
Function: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
Subcellular location: Secreted.
Interaction partners:
- Gastrin/cholecystokinin type B receptor
- Cholecystokinin
- Somatostatin
- Cholecystokinin receptor type A
- Pro-glucagon
- Appetite-regulating hormone
- Potassium-transporting ATPase alpha chain 2
- Potassium-transporting ATPase alpha chain 1
- Secretin
- Gastrin-releasing peptide
Sequence:
MPRLCVYMLVLVLALATFSEASWKPRSQLQDASSGPGTNEDLEQRQFNKLGSASHHRRQLGPQGPQHFIADLSKKQRPRMEEEEEAYGWMDFGRRSAEEDQ
Protein: Fe(2+) transport protein A (Ferrous iron transport protein A) (P0AEL3)
Organism: Escherichia coli (strain K12)
Function: Involved in Fe(2+) ion uptake. Does not stimulate the GTPase activity of the N-terminus of FeoB (residues 1-276).
Subcellular location: Cytoplasm {ECO:0000305|PubMed:23104801}.
Interaction partners:
- Fe
- Probable [Fe-S]-dependent transcriptional repressor FeoC
- Biopolymer transport protein ExbB
- Biopolymer transport protein ExbD
Sequence:
MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAPLGDPIHIETRRVSLVLRKKDLALLEVEAVSC
Protein: Succinate dehydrogenase subunit 4, mitochondrial (Q942X4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Succinate dehydrogenase subunit 7
- Succinate dehydrogenase subunit 5
- Succinate dehydrogenase iron-sulfur subunit 2, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase subunit 8B
- Succinate dehydrogenase iron-sulfur subunit 1, mitochondrial
- Succinate dehydrogenase subunit 6
- Succinate dehydrogenase subunit 8A
- Succinate dehydrogenase subunit 3-2
- Succinate dehydrogenase subunit 3-1
Sequence:
MASRLLARSKALALALSRADAAAPGPAAGVQWLRTLSSLPRDPAAAASPAPAPRQPAVGSPLGLSKIPGYEQTSRLSGTQVLPRWFSTGTSNGSSAQQEGATRKVMAFSPLEASIAKPRKGPLTSESWKVKQTELLTRSTYYMIPTLLLVSKNSISTSLLVASVFHQVYMFYKEILLDYVHHDITRKWVFIYFKILLIIMAKETVVYFDLF
Protein: Uncharacterized protein (Q57VK1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRSVHQSKGAFTLMLFMALLLSLLGGVLASTFHEYSKEQIFLLRRSGVLKDGWHNISRPPYSFYSGGETGKELEDIYSMSVGQLKNMLRDRQVSCVGCVERGHLVERVVEMRHQPTMEQLVVEELILMENVPLEYELAFAVGAVGGRQDGAAELEVEEE
Protein: 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase (EC 2.1.1.167) (2'-O-ribose RNA methyltransferase SPB1) (AdoMet-dependent rRNA methyltransferase SPB1) (S-adenosyl-L-methionine-dependent methyltransferase) (Suppressor of PAB1 protein 1) (P25582)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Specifically methylates the guanosine in position 2922 of the 25S rRNA at the stage of 27S pre-rRNA maturation. Methylates also the uridine in position 2921 in the absence of methylation of this residue guided by snoRNA snR52 at the stage of 35S pre-rRNA maturation.
Subcellular location: Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03163, ECO:0000269|PubMed:10648622}.
Interaction partners:
- Nucleolar complex-associated protein 3
- Ribosome biogenesis protein NSA2
- Ribosome biogenesis protein ERB1
- Ribosome assembly factor MRT4
- Ribosome biogenesis protein NSA1
- Ribosome production factor 1
- 60S ribosome subunit biogenesis protein NIP7
- Nucleolar GTP-binding protein 1
- Ribosome biogenesis protein YTM1
- Ribosome biogenesis protein RLP24
Sequence:
MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPRLLDPKEVFEELPDGQQNMESKIYNPEKKVRKRQGYEEGDNLLYHETSILDFVRTEDPISMLGEMNKFTIDENDHEWKILKKLKQTTDEFRSCIEDLKVLGKKDFKMILRWRKIAREILGIEVKDDAKTEIEVVPLTEEEQIEKDLQGLQEKQRLNVKRERRRKNEMKQKELQRMQMNMITPTDIGIEAASLGKESLFNLKTAEKTGILNDLAKGKKRMIFTDDELAKDNDIYIDENIMIKDKDSAADADDLESELNAMYSDYKTRRSERDAKFRAKQARGGDNEEEWTGFNEGSLEKKEEEGKDYIEDNDDEGVEGDSDDDEAITNLISKLKGQEGDHKLSSKARMIFNDPIFNNVEPDLPVNTVNDGIMSSESVGDISKLNKKRKHEEMHQKQDEADSSDESSSDDSDFEIVANDNASEEFDSDYDSEEEKNQTKKEKHSRDIDIATVEAMTLAHQLALGQKNKHDLVDEGFNRYTFRDTENLPDWFLEDEKEHSKINKPITKEAAMAIKEKIKAMNARPIKKVAEAKARKRMRAVARLEKIKKKAGLINDDSDKTEKDKAEEISRLMRKVTKKPKTKPKVTLVVASGRNKGLAGRPKGVKGKYKMVDGVMKNEQRALRRIAKKHHKKK
Protein: Photosystem II protein D1 (PSII D1 protein) (EC 1.10.3.9) (Photosystem II Q(B) protein) (P0C433)
Organism: Oryza sativa subsp. indica (Rice)
Function: Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01379}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01379}.
Interaction partners:
- Photosystem II CP43 reaction center protein
- Photosystem II CP47 reaction center protein
- Photosystem II D2 protein
- Cytochrome b559 subunit beta
- Cytochrome b559 subunit alpha
- Photosystem II reaction center protein H
- Photosystem II reaction center protein K
- Photosystem II reaction center protein M
- Photosystem II reaction center protein I
- Chlorophyll a-b binding protein
Sequence:
MTAILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAALEVPSLNG
Protein: Nuclear factor 1 (F7EL25)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU000690}.
Interaction partners:
Sequence:
MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKAEVKQKWASRLLAKLRKDIRPECREDFVLAVTGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAACAHPVLCVQPHHIGVAVKELDLYLAYFVRERDAEQSSSPRTGVGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASAGMRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPNSPTSSSRNWTEDMEGGIARSPHPSSALHFPATPILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPATQQPGPPALRPARPLQTVPLWD
Protein: LD32875p (Q5BI36)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MANINAVNMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKPSSDTALHIICNYGPDNTPEIMEVVKKILQRQLNINIQNIKGETPLHIAIARRNVEMVKLLLKVPNIDINLRTYDEKCALELSLSMGDHEFLIASILLSMGARTDRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLTALHIAALNNMPNLVKKLIVNGASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIRGGSDVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGESPLWSALEKGYEDVAKILVRHGIDTDCWDEGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSSRQPGPNGEGGDEAQDKASPLHLCCHWGQTKVLQTLIDHGANVNLIDAESKSPLHVAIESQYDEIISILLCHPDIDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFLLAIQVDVNSRVHDANQSSPLHLAAASQNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDATDADGNNALHIAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHELCRVVEDSTAGLICELFLESMPKYPINIPDMDGNTPLLLSFMRGQSPLCKILVKAGACLGTENKDGINIFNFKLATDQLLHNLLDQLPQESPWAESDYCQHCTNRFTITMRKHHCRHCGRVLCSKCSCNDVPILKFGINKPVRVCTVCFNVLQCGNGSLS
Protein: Sulfotransferase 1A3 (ST1A3) (EC 2.8.2.1) (Aryl sulfotransferase 1A3/1A4) (Catecholamine-sulfating phenol sulfotransferase) (HAST3) (M-PST) (Monoamine-sulfating phenol sulfotransferase) (Placental estrogen sulfotransferase) (Sulfotransferase 1A3/1A4) (Sulfotransferase, monoamine-preferring) (Thermolabile phenol sulfotransferase) (TL-PST) (P0DMM9)
Organism: Homo sapiens (Human)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:8093002}.
Interaction partners:
- Sulfotransferase 1A1
- Sulfotransferase 1A2
- Thrombomodulin
- Aspartate aminotransferase, cytoplasmic
- Sulfotransferase 1C2
- Sulfotransferase 2A1
- Steryl-sulfatase
- Sulfotransferase 2B1
Sequence:
MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL
Protein: B6.2 (Q90747)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MDFNSPFILQCWLVITTVTDGSATMIGALSGSSAKFPLGVENLQNVLKMSWKNSNCSTAVVDDTLLAECHPSSKRCLKLENGSLVLRRVEKEDEGNYEFFFNDTKVLFTLEVFEPFIDAWCFPNGTADLTCNVDSNENMTFEWKLNNSWPNANGACVKDGGKKVRLEKTVPGEFVCKVTYNNGFVWTRPIVLSCSYGDLLQYPWFIYILAGCAGAAAILVAVVSSLICCCMRRKHKFLPVPSDEEKDDGITMSVVSSEGVKSPPNGDHVEAQAAQIACPPMPDAARPDSGIVPQPMVEENFPVAVEPGEMPDPEMIADVESQENASNCFPDPIDN
Protein: Calcium permeable stress-gated cation channel 1 (Transmembrane protein 63C) (Q9P1W3)
Organism: Homo sapiens (Human)
Function: Acts as an osmosensitive calcium-permeable cation channel. Required for the functional integrity of the kidney glomerular filtration barrier (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:35718349}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q8CBX0}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes at mitochondria-ER contact sites. {ECO:0000269|PubMed:35718349}.
Interaction partners:
- Inner centromere protein
- G protein-activated inward rectifier potassium channel 2
- Aurora kinase B
Sequence:
MSASPDDLSTGGRLQNMTVDECFQSRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSETSLEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWSSHFARTTIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSLHAITIFSLSTLLIAMVIAFVGIFLGKLRMVADYEPEEEEIQTVFDMEPSSTSSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMNNQPEEGEEESGLRGFARELDSAQFQEGLELEGQNQYH