wanglab/gogpt-training-data huggingface dataset:
Protein: Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) (Q55EI0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).
Interaction partners:
- Putative actin-23
- Actin-3
- E3 ubiquitin-protein ligase
- E3 ubiquitin-protein ligase
- E3 ubiquitin-protein ligase
Sequence:
MERFLMQSSLSTSSLIYPHGSYDSSCNYCDAGEDKKGRICYGMVADQLTCEDYQLLIDQGWRRSGTFLYKPNNSDKKTCCPQYTIRLDTSSFKPSKDNKSTIKKFNNYILNNIIKEKDSSTTSTTKDIINTTQIKSNTKNNNNKTNDENIIKLNNDIIEIILNNEFINKFNEQDKKILKENLKIKINSNKMIKETGSYSLSFGIFNKYRSELNQHSITIDQIINFTILEFNKTINNSDYQFNLEKGQNNHINFKMINSSQILNDSTKTKTLNIQNNSNKNSTTTATTATTTTTTTNEPKHKFEISIHKPKCTDEVFSLYCKYQKIIHKEDDEKTKSGFKRFLVDSPLIPIIHPDESYDDYVYDGKDDDDDDDDKDEKEDDEDEDQEDDEDEDDGNNEDEKKITKENKEKEIKNHIYKIGKKSKTLKTRKFGEIKTPKPGYGSFHQYYRLDGKLVGVGVIDILPECLSSVYFFYDPDFNFLSLGKYSALNEIEWVQKVSQSIPQLKYYYMGYYIHSCQKMKYKANYQPSQLLCLETFKWVEFKKAISFLQPDKKYSRFYFDENENNNNEKLTYFEKEPELLERVKFRQKNFTFHFSDVSVRFQNLLKDQVIDYINHVGPELTKELIFYFK
Protein: 1,4-beta-glucanase (Q5TIQ4)
Organism: Acetivibrio thermocellus (Hungateiclostridium thermocellum) (Clostridium thermocellum)
Interaction partners:
Sequence:
MKLRYKVRRRRRIITCCGIIAAVIVVSTLIITIKNSFKPSRQSSNSNVTYSKENVQSVYSDRFIALFEDIQKQGYLSEEGIPYHSIETLLVEAPDYGHLTTSEAMSYMVWLGATYGKLTGDWTYFKDAWDKTEQYIIPDPERDQPGVNSYIPTQPAQYAPEADSPEKYPTPGDINAPTGIDPIADELASTYGTKAIYQMHWLLDVDNWYGYGNHGDGTSRCSYINTYQRGSGESVWETIPHPSWEDFRWGQVNNGGFLKLFGNFGEPVRQWRYTSASDADARQIQATYWAYLWSKEQGKEKELQPYFEKAAKMGDYLRYTFFDKYFRPIGVQDSGRAGTGYDSCHYLLSWYASWGGDINGTWSWRIGSSHCHQGYQNPMAAYALAKESIFTPKSKNAKKDWEQSLDRQIELFLYLQSAEGAIAGGVTNSWSGAYGKYPEGTSTFYDMAYDPHPVYNDPPSNRWFGFQAWSMERIMEYYYLTGDSRVKELCKKWVSWAIENTRLKSDGTYEIPSTLEWSGQPDPWTGKPSENKNLHCTVTEWTVDVGVTASYAKALIYYAAATEKHEKKIDDKARETAKQLLDRMWHNYRDKKGVAAKEPRADYKRFFDEVYIPHDFSGINAQGAEIKNGITFIDLRPKYKEDKDYKMVEEAIKSGKDPVMTYHRYWAQAEVAMANAMYHIFFEQKKDGLVPGINSDDSNSSSETQKSETPDYTPDSLSTSDATITESPANTNSPDENPSPQNTSAPTNVPLNPANTPYNSSNAAPNSPNTPARPSNTTAGSPAGNNTVGRLILQYANGNGSDTTNTINPRFKLINNSGSPVKLSDVKIRYYYTIDGEKGQQFWCDWSSAGNSNVTGKFVKLTSPKNNADYYLEIGFTEGAGSIEPGMSVEVQARFSKDDWSNYSQANDYSFSASANDYGNSNHIALYISGRLVSGNEP
Protein: 14-3-3g protein (D9Z6D4)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MSPTESSREENVYMAKLAEQAERYEEMVEFMENVAKTVDVGELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEDHVATIKEYRSKIEAELSKICDGILSLLESHLIPSASSAESKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLLAYKSAQDIALGDLAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAISELDTLGEESYKDSTLIMQLLRDNLTLWTSDITDEAGDEIKEASKPESGEGQQ
Protein: Probable phosphatase SPAC513.02 (EC 3.1.3.-) (Q9UT63)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MASKGIDKTIYFVRHGQVSHDVDENGVHREHDPLLNDEGRKQALQLQHDLDAEKLPIELILVSPMRRALETMKIGFQHYIEDKHIPVKVIPLLQDCGDWACNVGSYTKDLEKQFPGYDYTACHEDPVFPKKEKIYKADYKTSIQRSRVLAEFFAKVPEKVFAVVTHGVDIRLFQKIQKPEDSLDAVPKEHSFSPCQHEEFRMHYEDDKNWNFEPVK
Protein: Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Q55EZ6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}.
Interaction partners:
- Coatomer subunit beta
- Coatomer subunit beta'
- Coatomer subunit gamma
- Coatomer subunit epsilon
- Coatomer subunit alpha
- Probable coatomer subunit zeta-A
- Probable coatomer subunit zeta-B
- Emp24/gp25L/p24 family protein
- Centrosomal protein 103 kDa
- TSET complex member tstD
Sequence:
MVVLAAAICTKNGKALLSRQFSEMTKSRVEGLLAAFPKLIGLGRQHTFIETENIRYVYQPLESLYIVLITNKNSNILEDLETLHLLAKLVPEYSNFDEYDISKNAFELIFTFDEVIAMGYKERVTLQQIKHFISMESHEEERFRMEEKIKQKEAQILASSKAKEIERMRHEEMLRGKRSGGYTGISGGGGMGSGGMGSNQYRDNDRDNYHSNNNNNNNNNNNNNNNNNNNRDRDRGDSPNTSRPSAASSGSQGGMILGGKSGTNKNSAIAQVLKEEKIVEKVEDVEQLLDSQISQIPETPTVPQEGVHITVEESFTSFVESDGTVESIDIKGGLSVQINDQSLGKVKVNLKQGKLSKQFQFITHPNIDKALFGEQSVLRLRDGGKGFPSGGILKWRCKTNQESMMPIRVNCWPSPGRDSTTVNLEYDSLVGYELKSVFIVIPNPTSNAPIINQFDGLYEYDNKQKCVIWKIPLIDDSNRQGSMEFSVKGNTQSFFPVKIQFTASQTICDTTVGSVFVEDSNQSTNFSTETTLSVDTYEIK
Protein: Corticoliberin (Corticotropin-releasing factor) (CRF) (Corticotropin-releasing hormone) (P49188)
Organism: Xenopus laevis (African clawed frog)
Function: This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MKFQLWVSTGILLVSLLPCHECRAFIKSPASSPGALLPALSNSQPFLLRMGEEYFLRLGNLHKHSPGSFPEASAGNFVRAVQQLQAQQWSSQPGMRAASLDGADSPYSAQEDPTEKAKRAEEPPISLDLTFHLLREVLEMARAEQIAQQAHSNRKLMDIIGK
Protein: beta-glucosidase (EC 3.2.1.21) (Q2TYS6)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Probable glucan endo-1,3-beta-glucosidase eglC
- Glucanase
- Probable 1,4-beta-D-glucan cellobiohydrolase A
- beta-glucosidase
- beta-glucosidase
- Probable beta-glucosidase H
- beta-glucosidase
- beta-glucosidase
- Probable beta-glucosidase I
- Probable beta-glucosidase F
Sequence:
MVQLKSFLLLLNVAIARSALVWDDTYFYGQSPPVYPTPNMSGAGSWGHALSKAQHLVSQMSLEEKVSLTGGSKDSRNGCGGNIPAIDRLGFPGMCLQDGPNGIKGVELVNGYPSGIHVGASWNKSLAYKQAKAIGGEFRRKGATIALGPPVVGPLGRIALGGRIWEGYTNDPYLSGILAAEAVRGVQDNGVISCAKHFVGNEQELHRNPRPGGPGNRTVEASSSNMDDKTMHELYMWPFADVVHAGVASVMCAYQRLNNSYSCHNSKALNGLLKTELDFQGFVMSDWGAQHTGIASALAGLDMVMPSGNKYWGAKLIEAVRNGSVPESQITNMATRIMAAWYLSNQDDPSLPPVGAGIPADFERQHPVIDARDPHDESLLLEGAIQGHVLLKNVDNALPLTNPRILSIYGYDAKAPDSNFAQAGLNDWTLGLESHDSRTVVCGFASIGGDCPDFPPIAINGTIISGGGSAAVTPVYISSPFQALEARARQDKTQLFWDFKGTEAVNSEADACLVFINAASSEGVDRPALRDDYSDGLVLGIASRCNNTIVVIHNAGVRLIDQWIEHPNVTAVIFAHLPGQDSGEAITQILYGDVSPSGKLPYSLPRNESDYGSLLTPVTFTDWDQLFPQDDFAEGVFIDYRAFDMKGIAPRFEFGYGMTYTTFKYSNLTIRWTVDPSDLSEYPEGPVIPGGNADLWENIAAVTAGITNTGQMEAAEIAQLYVQIPGEGQPLLELRGFDKVAVPPGETRTVDFNIRRRDLSTWDVAAQKWKLSVGAQYPVFVGSSSRKLLLNGTLYL
Protein: RHO GTPase-activating protein RGD1 (RhoGAP) (Related GAP domain protein 1) (P38339)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: GTPase activating protein of RHO3 and RHO4. Acts in concert with MID2 in cell integrity, which is functionally linked to the PKC pathway. Involved in various stress responses. Required at low pH for activation of the PKC pathway. Important during mating response.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:23454383}. Note=Bud and bud neck. During isotropic bud growth in the G1 and S phases, detected at the bud tip. During cytokinesis, undetectable at the bud tip and localized at the bud neck only.
Interaction partners:
- Protein FYV8
- GTP-binding protein RHO3
- GTP-binding protein RHO4
- GTP-binding protein RHO2
- Cytokinesis protein 2
- GTP-binding protein RHO5
- Cell wall integrity sensor MID2
- Rho-GTPase-activating protein LRG1
- GTP-binding protein RHO1
- Rho-GTPase-activating protein RGD2
Sequence:
MEETAKKPASATVSAKSSHDGGTDDLAHLFSTPEIKKVLNSDVAINALLSRLKQSLLTCEEFMKFIRKKYAFEEEHVQELSKQYKHFFNIQGSTNSSLKKMIHEVLGFDGKMAQVKQSYITALQKMYSEISSLLLTMTKLRKSVKENSKRLEKDVSDAIHSAEKAQSRYNSLCQDWDKLRMTDPTKTKLTLRGSKTTKEQEEELLRKIDNADLEYKQKVDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLNTGVTISPLDSTKSMKSFAGSVSNERDLYSFLNKYNQTGKHSLLINKNLIPVSYKKHPSMNHGQKNKSPPKFAVDPSRNSIPKRMISTHNESPFLSSSSNTAAVPNANLNSATPSLNTNKQLPPTMASSISSTSNAAGAMSPSSSIVTSDTTSSITKTLDPGNNSPQIPEELINSLDSDRPISHIQTNNNMPPGVQKNFKTFGVPLESLIEFEQDMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDVNFQIMAMEVLLEVSDQAFEPE
Protein: Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9 homolog) (Q8VYP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Polynucleotide 5'-kinase involved in rRNA processing.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Las1-like family protein
- Protein ROOT INITIATION DEFECTIVE 3
- Protein VTE6, chloroplastic
- Ribosome biogenesis protein BOP1 homolog
- Ribosome biogenesis protein WDR12 homolog
- Pescadillo homolog
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- Rix1 complex component
- tRNA-5-taurinomethyluridine 2-sulfurtransferase
Sequence:
MSEAENKLPFIPEEWSNAASSVSCSSLQPVIALVCGPKNSGKSTFSRNLVEVLLQRYKRVAYLDTDVGQPEFTAPGFLSLTIVDKSILESDWTVPCVKTPERCFFYGDVSSKRDPKAYLRYVYTLFDYYQLHFCKSSENKTELPLVINTPGWVKGIGYELLVDVLRYVSPSHVVKINISAYNKNLPAGLFWLDGNDDETAHLIEIQSAYQDRYNQSILIHKDARLMRDMRIIAYFRQCFKGKEVNTIKELTHELASHIPYEVPISSLTINHLHCQIPSSEVYYSLNASIVGLGISTEVFEDLPSCVGLGIVRGIDTERGILYVITPVPENLVEKVDLLLQGYIQLPTCLLEVKDYRSPYLSANVLAST
Protein: Probable 26S proteasome regulatory subunit rpn3 (O42897)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Interaction partners:
- 26S proteasome regulatory subunit rpn12
- Probable 26S proteasome regulatory subunit rpn6
- 26S proteasome regulatory subunit rpn10
- 26S proteasome regulatory subunit rpn1
- 26S proteasome regulatory subunit rpn2
- Probable 26S proteasome regulatory subunit rpn9
- 26S proteasome regulatory subunit rpn502
- 26S proteasome regulatory subunit rpn7
- 26S proteasome regulatory subunit rpn501
- 26S proteasome regulatory subunit rpn11
Sequence:
MIDDQRDMQVDSVNQEENVDSGETKQNTVTEVPRTVLQDVEANIAALMQATKQRDPRLVYRSLRTTSNICHRLNADVLGQLIKKYYSFDNSLKNELLELIDMPQNGDDSSTSITNGNGNTIFPEVDMYLQLLLSMTLYYNEKYEVGAEYIKKVIARLQSYDRRTLDQIAAKLYFYYILFFEKCNRSVECRNTLLSVHRTASLRHDSETQAMVLTLLLRNYIQFNLYDQADRLVSKTSFLTNASNNLAIRYQYYLGRIRAIQLDYTTAHEHLVSAIRKAPNTVYAVQFLEAVYKLHIVVQLLMGEIPERRIFRQKSLEKTLVPYLRISQAVRIGDLCAFTDALSKYEAEFRFDGLYTLICRLRHTVIKTGLRMISLSYSRISLRDVCIKLGLDSEESAEYIVAKGIRDGVIDASIDHSNAFMASNEAMDIYSTEQPQQAFHERIQFCLALHNDSIKSMRYPMDAHKSELEGVEEARRRMDKEMAEADLDDDEPDLGEF
Protein: Nuclear factor 1 (A0A8I6AMP4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU000690}.
Interaction partners:
Sequence:
MEVPGPPVSGKPGETSVKWQLCYDMTAKMWWMDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKAEVKQKWASRLLAKLRKDIRPECREDFVLAVTGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAACAHPVLCVQPHHIGVAVKELDLYLAYFVRERDAEQSSSPRTGVGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASAGMRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPNSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPATPILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPATQQPGPPALRPARPLQTVPLWD
Protein: RAR related orphan receptor A (A0A0C4DG53)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Protein: 2-hydroxyacyl-CoA lyase (EC 4.1.2.63) (Peroxisomal protein 1) (P39994)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Peroxisome matrix {ECO:0000269|PubMed:26928762, ECO:0000269|PubMed:27392156}.
Interaction partners:
- Acetolactate synthase small subunit, mitochondrial
- Peroxisomal targeting signal receptor
- Oxalate--CoA ligase
- Peroxisomal targeting signal receptor 9
- Uncharacterized membrane protein YIL089W
- Dihydroxy-acid dehydratase, mitochondrial
- Hydroxyacyl-thioester dehydratase type 2, mitochondrial
- NAD-dependent malic enzyme, mitochondrial
- Uncharacterized protein YBL039W-B
- Alanine--glyoxylate aminotransferase 1
Sequence:
MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGEKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAFAWQNKPRL
Protein: Fatty aldehyde dehydrogenase HFD1 (EC 1.2.1.3) (EC 1.2.1.64) (Hexadecenal dehydrogenase) (Q04458)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. Involved in coenzyme Q (CoQ) biosynthesis, catalyzing the last step in the tyrosine to 4-hydroxybenzoate (4-HB) pathway. Oxidizes 4-hydroxybenzaldehyde (4-Hbz) to 4-HB, the aromatic precursor for coenzyme Q.
Subcellular location: Lipid droplet {ECO:0000269|PubMed:24868093}. Mitochondrion outer membrane {ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:16407407, ECO:0000269|PubMed:16689936}; Single-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:14562095}; Single-pass membrane protein {ECO:0000255}. Cytoplasmic granule membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Acetyl-coenzyme A synthetase 1
- Acetyl-coenzyme A synthetase 2
- Polyamine oxidase FMS1
- 4-aminobutyrate aminotransferase
- NADP-dependent alcohol dehydrogenase 6
- Acyl-coenzyme A oxidase
- Glutamate decarboxylase
- Acetyl-CoA hydrolase
- Alcohol dehydrogenase 4
- NADP-dependent alcohol dehydrogenase 7
Sequence:
MSNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKKDLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYPSFDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQPYWNDFTLFMRYPPNSAQKEKLVRFAMERKPWFDRNGNNKWGLRQYFSLSAAVILISTIYAHCSS
Protein: UPF0149 protein YgfB (P0A8C4)
Organism: Escherichia coli (strain K12)
Interaction partners:
- 2-octaprenyl-6-methoxyphenol hydroxylase
- 2-octaprenylphenol hydroxylase
- Xaa-Pro aminopeptidase
- N
- Ancillary SecYEG translocon subunit
- UPF0162 protein YchA
- Protein Sxy
- LPS-assembly lipoprotein LptE
- Cell division protein ZapA
- Regulator of RpoS
Sequence:
MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDSSWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH
Protein: ABC-thiol transporter (EC 3.6.3.44) (Q4QBE9)
Organism: Leishmania major
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Aquaglyceroporin
Sequence:
MATPDFVRLSPTDESSELINHAPSQLRHTQCGADNSHTTIITDLEAVDDAAHVRCQQQVQREFAEQLEELWGGEPTYTPTVEDQASWLQQLHYGWIGDYIYKAAAGSITEADLPPPSRSTRTYHTGRKLSRQAHADIDASRRWDGYVGCEVMYEAEAETSGVLRWVGYLQQSDYPRSLVAGVEWRVPPRYRRQATPGSAAGLHNGVVHGERLFRPYQDNYLCSCEPVDRLYLSSTCGLMRPGPPPSPDLLLTLFKAHWYHVWVQILPKLLADLTALMLPVLLEYLVKYLDADNATWGWGLGLVLTLFLTSVIQSCAAHKYDHISIRSAALFETSSMALLFEKCFTVSQRSLQRPDMSVGRIMNMVGNDVDNIGSLNWYVMYFWSAPLQLALCMLLLIRLVGWFALPGMAVLLVTLPLQGAISKHIQEVSERMASVVDLRIKRTSELLSGIRIVKFMGWEPVFLARIEDARSRELRCLRDVHLANVIFMFVNDATPTLVIAVVFILYHASGQALRPEIVFPTIALLNTMRVSFFMIPIIISTVLQCLVSTKRITTFMECPDTRSQVRDIAGIASAGAAAIFKDVSIHTYLPAKLPRCKSRLTTMQRITLWFCRRGVPEAEWYELDGPDAGASSPTGHIPAFEMGSAQAASADGDGAGTGGGDEEANVEEADAQYYQVVSKELLRNVNLVIPQFKLTMVIGATGSGKSTLLGSLMGEYDVQSGEVWAERSIAYVPQQAWIMNATVRSNILFFDEERAADLQDVIRCCQLEADLAQLSGGLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGQRIVQDVICGRLRGKTRVLATHQIHLLPLADHIVVLQHGRIAFAGDYADFAATSLEETLRGQLRENKDAESSGSEVDAEAARAETAPGLAEAHEPKVEQEANVAGGEAPLTFDVEAGRLMTREEKATGQVPWSTYVAYLRSCGGLAAWGFLLATFVVTETVTAANGVWLSIWSTGSLRWSADTYLHVYLFIVFLNIFCSPLRCFLCYYLMRVGSRNLHRDLLESIGVARMSFFDTTPLGRVLNRFTKDMGILDSTLNDSYLYLLQYFFSMCSKVIILSAAQPFVLVAIVPCVFIYYKLMQIYSASNRETRRIKSIAHSPVFTLLEESLQGQRTIATYGKMHLVLQEALRRLDVVYSALYMQNVSNRWLGVRLEFVSCVITLVVALIGVIGKMERASSQNIGLISLSLTMAITLTETLNWLVRQVAMVEANMNSVERVMYYTREVEHEHVPEMKELVAQLIRSESGTAADVTGTVVIEPASPTCAAPHIVQAGSLVFEGVQMRYRKGLPLVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGSYGLRELRRQFSMIPQDPVLFDGTVRQNVDPFLEASSAEVWAALELVGLRERVASESEGIDSCVLEGGSNYSVGQRQLMCMARALLKKGSGFILMDEATANIDPALDRQIQATVMSAFSAYTVITIAHRLHTVAQYDKIIVMDHGAVAEMGSPRELVMNRQSIFHSMVEALGRRVAKDFVELLG
Protein: Aureusidin synthase (AmAS1) (EC 1.21.3.6) (Q9FRX6)
Organism: Antirrhinum majus (Garden snapdragon)
Function: Involved in the biosynthesis of aurones, plant flavonoids that provide yellow coloration to flowers. Can use tetrahydroxychalcone (THC), pentahydroxychalcone (PHC), THC 4'-glucoside and PHC 4'-glucoside as substrates, but not 2'-hydroxychalcone, 4-hydroxychalcone, PHC 3-glucoside, 2',6'-dihydroxy-4,4'-dimethoxychalcone, naringenin, eriodictyol and 4,4',6-trihydroxyaurone. Can also produce bracteatin from PHC.
Subcellular location: Vacuole lumen {ECO:0000269|PubMed:16367960, ECO:0000269|PubMed:16832053}.
Interaction partners:
Sequence:
MFKNPNIRYHKLSSKSNDNDQESSHRCKHILLFIITLFLLIVGLYIANSLAYARFASTSTGPIAAPDVTKCGQPDLPPGTAPINCCPPIPAKIIDFELPPPSTTMRVRRAAHLVDDAYIAKFKKAVELMRALPEDDPRSFKQQANVHCAYCAGAYNQAGFTNLKLQIHRSWLFFPFHRYYIYFFERILGKLINDTTFALPFWNYDSPGGMTIPSMFIDTNSSLYDSLRDSNHQPPTIVDLNYAFSDSDNTTTPEEQMIINLKIVYRQMVSSAKTPQLFFGRPYRRGDQEFPGVGSIELVPHGMIHLWTGSENTPYGENMGAFYSTARDPIFFAHHSNVDRMWSIWKTLGGPRRTDLTDPDFLDASFVFYDENAEMVRVKVRDCLDEKKLGYVYQDVEIPWLNTRPTPKVSPSLLKKFHRTNTANPRQVFPAILDRVLKVIVTRPKKTRSRKEKDELEEILVIEGIELERDHGHVKFDVYINADEDDLAVISPENAEFAGSFVSLWHKPIKGKRTKTQLLTLSICDILEDLDADEDDYVLVTLVPRNAGDAIKIHNVKIELDG
Protein: Rac GTPase-activating protein 1 (A0A0R4IZK0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
METAVMNLHSIFESLRAQADVLNESIEPQFIQLAINFEDNRRRWLRLEQELNACKEVLTKAETERGALEVKLKHARNQVDVEIRRRQKAESDCAKLDRQIQLIRELLVSEGSSSSIQLNEEQRSALAFLNARSQNPANLNTSRRLATIDESASILSDISYDKTDDSLDWDSSAIRTVRLKKRQKRRSSRNHTEGPPAAAKRSRSTGRTSEKGNESLVAKTTVTVPADGGPIEAVTTVEAVPYWTRSRRKTAAVEWDTVDTDSVQSMDVFKQPSLPNAENRAEPSTPQGNGGVRLHEFISKTVIKPESCVPCGKRIKFGKISLKCRDCRVVAHPECRERCPLPCIPSMTGTPVKIGEGTLANYVSNTSPMIPSLVVHCINEIEQRGLHETGLYRVSGSDRVVKDLKEKFLRGKTVPLLSKVEDIHAITGLLKDFLRNLKEPLLTFRLNRAFMDAAELSDDDNSIALMYQNISDLPQPHRDTLAFLIIHLQRVAQSPATKMDITNLARVFGPTIVGHAVSNPEPMTILQDTKRQPRVVERLLSLPVEYWSQFMISDHDHARNDHMIIENANVHTTPDQKMSMFGPITTPDQQMSKTPSSSSLSQRMKNATLNAITPKFSSRSRATAAVPRQGNFFASPLLK
Protein: Sulfate/thiosulfate import ATP-binding protein CysA (EC 7.3.2.3) (Sulfate-transporting ATPase) (P9WQM1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
Subcellular location: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01701}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01701}.
Interaction partners:
- Probable sulfate-transport integral membrane protein ABC transporter CysW
- Bifunctional enzyme CysN/CysC
- Sulfate transport system permease protein CysT
- Probable sulfate-binding lipoprotein SubI
- Sulfate adenylyltransferase subunit 2
- Molybdenum transport system permease protein ModB
- Multidrug efflux system ATP-binding protein Rv1218c
- Adenosine 5'-phosphosulfate reductase
- Phosphoserine phosphatase SerB1
- Sulfite reductase [ferredoxin]
Sequence:
MTYAIVVADATKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST
Protein: Large ribosomal subunit protein eL21z/eL21y (60S ribosomal protein L21-1) (Q43291)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL8z
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein eL42z/eL42y
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Large ribosomal subunit protein uL6z/uL6y
- Small ribosomal subunit protein eS6y
- Small ribosomal subunit protein uS12y
- Large ribosomal subunit protein eL30z
- Large ribosomal subunit protein uL23y
Sequence:
MPAGHGVRARTRDLFARPFRKKGYIPLSTYLRTFKVGDYVDVKVNGAIHKGMPHKFYHGRTGRIWNVTKRAVGVEVNKQIGNRIIRKRIHVRVEHVQQSRCAEEFKLRKKKNDELKAAAKANGETISTKRQPKGPKPGFMVEGMTLETVTPIPYDVVNDLKGGY
Protein: Endonuclease III homolog 1 (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase 1) (DNA glycosylase/AP lyase 1) (Endonuclease III-like glycosylase 1) (Redoxyendonuclease 1) (P31378)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines, but also purine-derived lesions, alkylation damage and cytosine photoproducts generated by UV irradiation as well as abasic sites. Has also 8-oxoguanine DNA glycosylase activity. The AP lyase can incise AP sites opposite all four bases. May also play a role in the regulation of mtDNA copy number by introducing a double-stranded break (DSB) at the mtDNA replication origin ori5, initiating the rolling-circle mtDNA replication.
Subcellular location: Nucleus {ECO:0000255|HAMAP-Rule:MF_03183, ECO:0000269|PubMed:10207101, ECO:0000269|PubMed:10471279, ECO:0000269|PubMed:19029246, ECO:0000269|PubMed:20194111}. Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03183, ECO:0000269|PubMed:10207101, ECO:0000269|PubMed:10471279, ECO:0000269|PubMed:19029246, ECO:0000269|PubMed:20194111}. Note=Relocalizes to organelles containing elevated oxidative DNA damage. {ECO:0000269|PubMed:19029246, ECO:0000269|PubMed:20194111}.
Interaction partners:
- Apurinic-apyrimidinic endonuclease 1
- Endonuclease III homolog 2 lyase 2)
- DNA-
- N-glycosylase/DNA lyase
- Uracil-DNA glycosylase
- Signal recognition particle subunit SEC65
- DNA polymerase zeta catalytic subunit
- DNA repair protein RAD14
- Phosphoglycerate kinase
- DNA repair protein RAD1
Sequence:
MQKISKYSSMAILRKRPLVKTETGPESELLPEKRTKIKQEEVVPQPVDIDWVKSLPNKQYFEWIVVRNGNVPNRWATPLDPSILVTPASTKVPYKFQETYARMRVLRSKILAPVDIIGGSSIPVTVASKCGISKEQISPRDYRLQVLLGVMLSSQTKDEVTAMAMLNIMRYCIDELHSEEGMTLEAVLQINETKLDELIHSVGFHTRKAKYILSTCKILQDQFSSDVPATINELLGLPGVGPKMAYLTLQKAWGKIEGICVDVHVDRLTKLWKWVDAQKCKTPDQTRTQLQNWLPKGLWTEINGLLVGFGQIITKSRNLGDMLQFLPPDDPRSSLDWDLQSQLYKEIQQNIMSYPKWVKYLEGKRELNVEAEINVKHEEKTVEETMVKLENDISVKVED