Protein: Huntingtin, isoform A (Huntingtin, isoform B) (Huntington disease protein homolog) (Q9V3N4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- TAR DNA-binding protein 43
- Superoxide dismutase
- Ataxin 1
- Hsc70Cb, isoform G
- FI18188p1
- Palmitoyltransferase Hip14
- Inositol 1,4,5-trisphosphate receptor
- Heat shock protein 83
- Kinesin light chain
- DnaJ-like-2, isoform A
Sequence:
MDKSRSSAYDKFVGFVEQLRNTECSQKQKITCFQQIAECIMSPSLAGHINYAAHCGTATNVLLLFCEDVDSVVRMSAEENLNKILRSLEKTRVSRILMDLYGEIKRNGNQRSLRICLNLFSYYAPQIKEKHIKWYAVRLLQCMTTISQRKETLLQETLCDFVKHFSRHIQQGLSDSESCKLFETFLDQISSDCAVKRRCSAQNCMSLIENARNRSLMARHGVNKVMELLLTDQQANSVLGALGLLRLLLPQLIRGYPGDSHEDSESLAGKKQQQQQTTTSDCRQIIEIYDYCLHLLSTQHTANHAIINATLEVINGILQAVDAASDGQCSQSLGQSLRQLLCNQQLQHNEYLRRRKSLKNQIFQLKNYEVATSQHQLEDEDENEDVDELVVGATAMQMKKNSNAKLQQAKCREQQQHQHQQQLEVDNSSLGINAGEDAPTEAPSSVADEGGEPESTKLRCHIRNAARSISECVASDEDKQGQGHRQQRDEDGVVVAEDDDDDDDDDDDDDDMELLSAECDDFTTLSQLNEQQQALSAALKLPTTTAASSGGAATSQDDKLIDVDADVGGLPKPQHQSSLQNLLAGSDDKSQHLSDIDNESFNSIDFDAEITIAGSKEQQQQHPPADDSVESGDATAIGTFFNNLLSHSNAASESVSKLFRQSSGSKSTPSKSASTPAPADKSDAISAASLTLSLTSLASSNLEPPERQPLIAETPTPVEDSCSITASHTASTALMMDAPAVEVAASKPETPQLRGTPNANPFLVENSPLRQTVVGRALITVKIGSILEQSLVYYTARLVAARFLLSGQAAGLQPDSISRVSIKSLSLAVIAQCVRLAPKILQLSLEISEQELQLLEEATSQIGSGDSTQVSSPQSSDNSQVGGEKPPLDSSLVPTSLEENLLLLDIKDDHFGPSTCPAYLQSATPTLSRSADASVLLLEGGTTSSRSAKKSEEMLSKSEIIESSYRPTVAVEDVPPLSMPPRPPKRTKSTRSRVGVLGTSSTTESSSPQSRQKLSDILLFHDHCDPILRGGVQQVVGNFLQSSGAGLFLDLQRGLGLQHLLAILLKGFEDEIHTVVIQALNAFDKIFPNVVSKYLTEPPCHYHAHQQQQQQQKEQQQQEQDNQKLEQDLQRHSSGQQKRSGQAQTFGQQTFAKDQDNALSSQRQQQRRPNDAGTCANSSATDNDELLAALLNDFQLQSTGMRQQPKNNSTDTGQSGNEPDLEPNPNAAVEPFCVFAISPKLLLSKLRLCHHNKYWLVQNKYAEVISNLNYVLLRSYYANFRCAIDNKNSGARKQDSKWPPMDASSVCHSVRDAEGEDIVCTYEAQFLAELLHLLGDDDARVREHAACCLCRFIMQTARQDPSQDQGAGGGGGDDIEGNGNVNVETQQTNFNLLWDFFDYRIFGSMSVTLRNLFRASSTIVPPLAELDALATSNSAPSYPDTGSTSGSSTSTSASSGGSAAAVSAASAYFEASYGIGIAEGHVFALASASQRQIAQEEKVLAKVLYRLTNKLMTLNDKNVQFGIIYALRLLLRHFNFVDYQQVWLEFNFVEICISYAYYNNATAADLGCQNDLIDVMGKLMAGAMLSSGEPNTAHLDFLLRHSVKMLNIYYHLVTNQRPPTAGSQSGSSSSKQPKSELFAREQPAATLQALGYFAGDYVYMKLYNILRGANDSYKITINQEAGSLLICLLKTCLHAVSLCLEGMASASPPELKLIEEILHYLTRLINYAPAECVACLRQLLKYLFAQNYASQVRLQPSAIGGNGSEIGHHAAFMRPYFAAKGRGHGASSTLLPTINSKPAVAVGSQRGAPTDARQPIDAGPLQDMGMLFVHGLQPPTPPAGDCVRLIKLFEPMVIYCLTLFMKSNALVQAPILRLLSQLLDLNVTYSILDSKNVIFDQVLSNMDLIEGGIDRNAFIMVPPMLRFLVQLTHKSDRQLITIPKIISITNNLLANGSVRVVALLALKTLSYELFFMHSQLEEALDTEGHNSGRDACQSPLSAAPTPETREALLAQRRELDTQREVVLGMLEKFIEARPSQQVLALLLLFERSVQQLDTPPYRSAQDADAVYGTLCRGLCSRQWRLHNAGDLRLLESCFRNNGNHVLADSKRFLQLLQLFIEQGVGNFGDLALAMVMLSNVILKTEEIYLVNHIKLYLKNNPTAERRLQALMPSSPSAAPHWQDEAPSTSSAAAAARAAAASFSAGRSSISEINYFAKVLCEKLLACLEVLLGLEPSSSSHAYCQLTGRFMDALLNVCCRSRHKDALQSVFRLVLAESEFLCKYYSLLLMSAAGLVGSYLLDAVLLACLRLVLAMRLEEPVALLEQAAQLPLKTNLQRALLREVCRASAGCDWSAQQVRRLFEGRYLNFLIADHLEFICELCQERPECGSLLQVALFRNAHRLSRQSVRIVLRLLGRLCEPAEREASGDVGSDADPTLQAMQLLSRLHQLYEGERSLQLPIERMARRLSAQSGQPARNVIYERLVEGDLAGGEDQDALRTLLLKDLECRQDNETATPSRIIDESWLFAQLIKFATQHADAPQQQKQLMLLLLEIQSEPKLQRLLRSLGTEHEAKLLRHAIAGSLAAMMSAFRQKCIQHAPHINYMQPTPLARVSCALLMSRVASTEATKCRNPPTGEQLDVARAVGALMACIRNAEQTALIYIDARLMEKFVVEHLLRREHLPQLLAYLGWLAGAAKQILAMPTRQESEQDALGVLLATVNTLLQQPRVWRELNASSDPSLRCELLDLLDSVARCILQDTIFYRRHRRDRNKAKGPAPQAIFLAKLIETQIEIESLASGRVLAGVEEARLQFAGQDLARFQVALSLVTSIGISLLRTHQFYAYAVTPHELIQQPGDQQQEQQADGKLPSIPVDSLSDVDVLRQFVKRLSIFGFTTRQQFEEYFMTCLLLINKLYDEHMVDQQEQFQIKQVCLQAILELLMTYKTFPIVGLANGQFHHTTRWQRITCDSISLKKLHKVQLLVDACNVFYQPNLERQLAYDNVIGTRTFAPNQYDLNFSWAQMEDQAAAGVGVGVGVGLSGGEQANTADIKQSCDADVPDMAMRNYRHFTQLSGIDFRSSTQLVFDVLQQMIELNHILVLPNLVKFCEICESRDHIKWIKERCLKLQEQVAMDDTISHQHIIYLLCRSQALLIPSLGELQVLCSLIGNVYLKSTHSFIRIATLQGLLCLLECCSKTNTTMGRLSEELALLRSLIVGYINRHGIIDESPLPFSVEHTKLVWTLNYSLIEWTSKFVPQCHLLSNTIIAANNFLKTTADEELYLCVLHGLERMVVNSGVPPPGIQPTGKDAAAGEPGAEGSKAGVGVVVTPQMRHKIEKLALELLKMENEKFSIPALKLLLSCMYVGSAAQLENTELSNGIVQDDPEIIAQQNDKVDILLHCIKSSTRDAAWIYGQVLCQIIRDLVPPNEILTKVIKEFLAINHPHCDVIAMIVYQVFRSAIDSSYLQMLQDWLICTLPTFLDQPEQQGVWGLSVIFLSASINLHLIKLFPLVLGIGASNSAAAATTATTATTEAEAAAPAMARKLGQHEIALFVTAAQDFHAKLSGEQRQRFREAFGSFKRSQVYGRMLQCL