Protein: Cytoplasmic dynein 2 heavy chain 1 (D6XEZ2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Tubulin beta chain
- Tubulin alpha chain
- Cytoplasmic dynein 2 heavy chain 1
- Dynein heavy chain, cytosolic, putative
- Uncharacterized protein
- Ras-related protein Rab-7b
- Cytoplasmic dynein 2 light intermediate chain 1
- Dynein light chain
- Dynein light chain
- Dynein light chain
Sequence:
MVSAEKDISDVCVDVAGETLKQLGASVSSTNRRSDVVELQIAVGSEKCPPIAAALFSGFVKAACGSEAGTTKVGLTDVNIDARENFTVLRFAEAVRVRDLDFNELPGDSPPITSVVEVTYMRYLIKHSELQVFQVSDFPKCLTPRGGQRLDTVVAGYVLFSLQSSEEDDTKVLLYMKSLRRVLGGMCTSSFAETVLSQAWGNMDSVEPSHVTDMLEDAQMAITDFWNDSDQDTAIRTKVVFLMKTVGSNLREYFAKKTLDAGGVFSGSKNITEVALGCCDEWVNMCKRLTTVDWGSSWGTAFEDVQLITVRDRLSVVVSIRDLVDEIVELLTAADKLQSLRTETLWETFDSLDIFATTPAVEQLWTNCLDAFYRRLQPVEHRCASALSDFFGERGNLAPQTILNEVVKFRQLIRRPAVSKELVNERDALLAKLNERLQSIRMEFERRSESVEDDVALDEEDRRCQAGRFMPGVVNNMIWLRQLRGRTSDMISMCKSLLNDLQNAGEFLRSANTLMEEIDDYVIETFKQWTMDVEGSKHVLMLDANAPLMDIAGDGSVRVNYPERLVQLIREVRIFRSLGFRISTAIQEMVDQGIRFYRNGVALKQVASTYNSMKENIIPCTQAMLLEPALAFENIITASGDRKLTWRNTDDAERFIGKLRRASQALTDANRRLHKLHREIESIVIELFSIDLLRLRERWTGKVRLIREKMETSGFNNMESWKQFWDMQIYKALEHQYQLGLESLHEVVAEIKADITYDPDTGLATLRPNIDVIRGQYYQRIKDFITFPLRFRGCGNSDIFGAMPGNNERGIFAVMKHAAQLFKKVQQELKRFHPLLVIGRCGKGGNPSLEDIVGHTLKEVQHWEQSVRLLKQKGKEINAEELFIKCGCITICTAGVKGTVEDHLHKLSQVLHVTLRDSAQKNLSRIEEYIAEVTTALGARLTKLEEIGAANLQHAKLMEKRPAVEVEFHHLHNKNVLLQSMANKSDFDFRGVKQRWDEVTRRLDAFEREMEKQVDSLKMSVEDTVSAWMKNLERFSNQWHEVKPKTVDTPNAMKIVTERREQFKALKAEGEECIQQCKYFQLDEPDIEELEDLERDIEEYVQMWDILVKFQEELDVLRAEPWIIMRAKCYRFEDFGRHWEEQLRTFSSSPITVHIRTLLDSWMRCLPVLKYLRGDGFTPSHWGEMFSLIGVRGVTQDTLKFGDVIDQHETLLRREADLKKLHARAQGEAQIREALDDVRSWGNNAKFTLIPHPDREGVKLITEWKDTMSALSDNQALLMSMKESPYFGIFANDANKWEERLACLDEYLRNMSQIQRKWVYLEPIFRRGALPQEQERFSRIDKEYLQVMKVVAADSRLVSLAGHTEFKDVLYTVLEQLDRCQRALNQFLEAKRDSFPRFYFISDDDLLEILAHSRNPSVIQSHLKKLFMGVHSVRFDDAKEHILQINSLEGEVVPIEESVLITEEVEEWLGRLDLAVKDTLKLHLVRCVDKVNIGAYSSQILSTAGLITFTKQTEDAIRDAKSGGLKKHRANLQAQLRELTTYAGGNSDVVIGLKVKALIMDLIHNIEVVDALIDAGIEKDTDWLWRKQLRFYMDYSDSCVLRMVGAEFRYSYEYQGNAPKLVHTPLTDRCYLTLTQGMQLGYGGNPYGPAGTGKTESVKALGNAMGRQVLVFNCDEGIDFKSMGRIFTGLVKCGAWGCFDEFNRLKVDQLSAVSQMIQVIQEAIKNGEPRCHLMGKEINVDSNAGIFVTLNPAGKRYGGRSKLPDNLKQLFRSVAMSVPDNELITRTILFSEGFENAVDLARKTVEVFKLSRDLLSFQTHYDWGLRSMKAVLRLGGTLIHEYLTERACGKVNPSPEEIFEKESEIIIKSLRVNTLSKLTFDDALLYNNLIADIFPGAPIKEIDYAELRPAIEESVKELKLQLVEAQIQKVLQLYEALRQRMGVVLVGPGGSGKSTLLLILRRALQRLGKVIPQYIMNPKALPRTQLLGYMDNDTREWFDGVLTEAARKVVKEETSVLSWIVCDGDIDPEWVESLNSVLDDNKLLTMPNGVRIQFGDNVNFIFETHSLEFASPATVSRTGIIYLSEEDVDPKMMVTSWLVEQPEDVRDKLERWINDYFYKAIDALLATGKLIVDTTRTGLVASGLSQLQGCTGKAQFALALVYGLGSYLTEEYRKDYAKEIHSMMSERLPDPKNPLDVYYDESSNCYRTFDVEPCTDLSVEDLYRDPMVATVDCQRNVKILQAWMKPVRPGIYRPFILVGPEGCGKKMLLTNLFGKTPGTRVTAVNCSAQTEATHVIQKLKQMCQVYNTNQGRVLRPKEVERLVLLLKDMNLPKPDKYGTVQLHSLLQQIVLYNGFYDTDLEWISLERVQIVGSMNPPGSMGRHPVAPRFLAMVSVLAMSYPSREAMQNIYTEFFNIMIQSGRLQLNLPGKGAVDIARIMTTVYEAVASRYTVNVASHYMFNPRDVTSWVLNLLNYNPEDVTNAIGYEGRRIFVDRLVTTEERSKISKVIHDNLIFLVGHKSGLSEKETTSFVSWMDTSPIGKKKLTPIANEELKKPAEDFVLGYSREFADLDVQLIPEVCVWMARVDRVLSQERGNLLLVGRSGVCAAGIVRLAAYGLRMELVTLGITREYSMKQFNAELKTIMMKAGVEGQHVVLLLEDHNFTVNSSFLETINSLLASGEVPGLFAQEELDAMTAPLKEDALGEGMSAYAYFVDRIARMLHVCVVMDPTNPNYEPQCRSNPALFTRCNVYWVGTWHTDSFKLIPRLLMRDVFKSIDSRDNKKDFSLTTEIVHVHKEYINTFSPQHFKGLCLTYESIFKEKSRMISEGITRLQTGVSKLDEAQENVDQIATDVVEKRKLMEVKQKEADDALQEIKTNMEAASDQKKNIQKIRKDLEKEQKAIEERKSVIEERLSGIQPTLDAALSAVRSIRSEHLSELKSLKQPPPAVQDVMEAVIITIGGGGGGDTNWASIRKILAGDIKEQIINFNIAGFTEATRLRVTQFMQNHENSFKREVIGRASKAAAPMAEWIKAVLEYSSVLQTMGPMQAELKEYEVSLASRSEKKRKYEEKLTKLEERVEGLKRNFGERTAEAERLKDHAEQAERLYACAHDLLAKLTSEHDRWVSQIKVIRENQVLLPKRCLLAAAFILYLGNATEDGRRTALNVWKERLKDVDNFEFFTFMRPESMQLHYKSEGLPGDELSMDNAVIIQEQVTTPLIIDSSGQALSWLVNHLKGKGLSVEVCSVSEERFVSSLELALRFGKSFILTDVDGIEAFMYPLFRKELRTEGTKRVIQFGDRRTVDYADGFQLYLVTNSTDLWIPPDVLSYLTPVNFSITQNGLEGQFLGATIQHEQPELEKEKLAVLQKEERLKMQLSDLEESLLKDLAESKGSLLDNKTLIDSLNEIKTQAAEISVALETSKKVQEEIDTKRNVYRPFAKTASEIFFIVKSLKALSHMYQFSFSFFMGIFNDTLHHHAEDRTDIDTKIDALTKTFVRSVVSSVCTSLFKEHRTVFGIHLARSLYPNDCTAAEWDFFLDRAIAPEAKKSEVRVPTWVLPDSRDLYRSFAVLFEDLTPKLSLHEADVWLQWMRSSNPEVSYPKFISQLSRFQRLLVVKTLRPDRLMAAVRSTACDMLHVKSYGDNNTLAQLLTRTEANTPILLITTTGADPSQELQAIAHQKVGRDHFHQLAMGGGQAEEAVRLLRACAESGDWLFLKNLHLVIPWVTALQKELNVLKPDSKFRLFLTSEAHDDFPSIFLSQCLKITFEAPPGVQQNLLHTYQDWESGPYDAKGTLHTQLLFITASFHAILQERRSYIPQGWTKAYEMTSADLKSASDIVLQQAKGETDWRAIRGLMEDAIYGSRLENEYDMRVLREYTDQFFNPNVLSSAKQQMNLFAKVKVPASGKHGDCLKVISELPENDIPFVFSLPPNADRVVQLSKVRALTDDLQLLIEARGESSMSREQWANKLRPILQVWEELMRPNPDLLQQTVSIARDASPILGFMGAEMTSSLRLVSIVDESMKDLGKVLEGQALLREDRRAEASTMIAGEVPAQWDNYYQGSPRILPWLQSLLHRATSIAKLFELATNGNLLKSSLNISTMFRPHTFLHALRQETAHSLHEPLVALRLVTSISTPPEGKTVPVCLEGLMLQGAVLDESNVLQSIEAADEAALFPMPKTYVGWMTTMPDSVTTVGVPLYTNGTKEMFLAELHLPCASELAAKAFILAGVALVLEP