wanglab/gogpt-training-data huggingface dataset:
Protein: WASH complex subunit 5 (WASH complex subunit strumpellin homolog) (Q54IR8)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- WAS protein family homolog DDB_G0292878
- WASH complex subunit 2
- WASH complex subunit 4
- WASH complex subunit 3
- Proteasome inhibitor PI31 subunit
- F-actin-capping protein subunit beta
- Ubiquitin fusion degradation protein 1 homolog
- Nuclear protein localization protein 4 homolog
- Maestro heat-like repeat-containing protein family member 1
Sequence:
MVKEFLGEGSQAGQNLLRLVSRGNAIIAELLRLSAHIPSVFKLEDRNEARKYQDILLDFKYLSNPDFYESKIEENADLVDLETEFRDNHIDILIRFYHLFESIYKYIMDLEHYIVDVEKGFYIHLTIEAILINGDGKQLLSEAVYLYGVMLILMDNLIEGPVRERMLISYLRNKGPVDLPLIDEVCKLCKSTGYIPGSPKKPPNYPEEYFRRVELPENVISMIVGRLRSDDLYNGTESFPQPEHRSVALSTQACMIYVILYFIPDILNNKNSIMREIVDKFFPDNWVISFFLGFTIDLSVAWEPYKAAKTAMGNTIIQSNIQYQTQRFWKEVSELNKLVDDLLVDGLLVEEYIVDNVHKIITTLRRCNVTIRWVMLHSNASQKKFKDLVLMGGSQEDVLYLLLNTAQLEFVFKNIFQQLLATKEEKWEENKKLASDSMVELSEYFSGEKALTRVKKNENLQKWFGEISQKISQLDSTDSTSTGRKIQQLSLALEEVEQFQQIDSSIQVKQFLIETRQFLTKMIKIVNIKEEVLVNLSVCADMSYAWEIVNNYVDQMQKGIKSDPKCVLKLRATFLKLVSILDLPLVRIAQCSSPDLISVSEYYSGELVGYVRKVLEIVPKQMFLILKQIINMQTNNIQEMPTKVEKERLRDFAQLDQRYDLARATHSVSVFTEGILAMETTLVGIIEVDPKQLLEDGIRKELVLQIALAMDKTLIFSGKPYQAPSNKQQQQEIELLQRLKELSNILDGFRRSFQYIQDYVNIQGLKIWQEEFSRIVNFYVEQECNSFLKKKVYDWQSQYQSVAIPIPKFPSQSDQNSQQSVNMIGRLARELLNQTNCKTTLYLNQIGWFDPSSGKELVGINTWSILHQSVGIFGLTGLDKLFSFMMVKDLQVFVSQTRSLVEKSLKGFLNEFEDYLRPTTNIPDTMIRYQQALDKTKLLYPIFIDVLTKIGQIQLIRRQISNQLNFHCKIDSNMLFSSLDIMNKSLLNDIESHFQRPDSNPYPSDDNTLLFDLAQYLDTAGINDPFTKIYITTSPLEQFPCLLFLFVLSQVSKFQFNSKLNVMSSKKQKNSYDWTPFIIGCITILQQFHSLHTQKFLAFVGQYIKSHINIALANPKENNKDDADYPEDVIGLLRFLEDFCKYSHTSRKIVEGYVPPYIFDYYNN
Protein: Thiamine transporter 1 (ThTr-1) (ThTr1) (Solute carrier family 19 member 2) (Thiamine carrier 1) (TC1) (O60779)
Organism: Homo sapiens (Human)
Function: High-affinity transporter for the intake of thiamine.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21836059, ECO:0000305|PubMed:10391222, ECO:0000305|PubMed:10542220}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Thiamine transporter 2
- Thiamine pyrophosphokinase 1
- Tetraspanin-1
Sequence:
MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS
Protein: Sorting nexin-10 (Q9Y5X0)
Organism: Homo sapiens (Human)
Function: Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption.
Subcellular location: Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=May also localize to nucleus and endoplasmic reticulum.
Interaction partners:
- Osteopetrosis-associated transmembrane protein 1
- Pleckstrin homology domain-containing family M member 1
- H
- V-type proton ATPase 116 kDa subunit a 3
Sequence:
MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
Protein: Large ribosomal subunit protein bL28c (50S ribosomal protein L28, chloroplastic) (CL28) (O22795)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000250}.
Interaction partners:
- Large ribosomal subunit protein bL27c
- 50S ribosomal protein L33
- Large ribosomal subunit protein bL31c
- Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain-containing protein
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Large ribosomal subunit protein bL21c
- Large ribosomal subunit protein bL9c
- Small ribosomal subunit protein uS9c
- Large ribosomal subunit protein bL21m
- AT5g15220/F8M21_110
Sequence:
MTTMATQGAWLRMTSSAKSMTKSTVTSKELGFLTSQLSGLRISYTPSDVINRISLPSFPGIQPIVARRICPFTGKKANRANKVSFSNHKTKKLQFVNLQYKRVWWEAGKRFVKLRLSTKALKTIEKNGLDAVAKKAGIDLRKK
Protein: Motility protein B (Chemotaxis protein MotB) (P56427)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity).
Subcellular location: Cell inner membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Motility protein A
- Flagellar motor switch protein FliG
- Sensor histidine kinase CheAY
- Flagellar hook-associated protein 1
- Chemotaxis protein CheV3
- Chemotaxis protein CheV1
- Chemotaxis protein CheV2
- Flagellar motor switch protein FliN
- Flagellar secretion chaperone FliS
- Flagellar hook-associated protein 2
Sequence:
MAKKNKPTECPAGEKWAVPYADFLSLLLALFIALYAISAVNKSKVEALKTEFIKIFNYAPKPEAMQPVVVIPPDSGKEEEQMASESSKPASQNTETKATIARKGEGSVLEQIDQGSILKLPSNLLFENATSDAINQDMMLYIERIAKIIQKLPKRVHINVRGFTDDTPLVKTRFKSHYELAANRAYRVMKVLIQYGVNPNQLSFSSYGSTNPIAPNDSLENRMKNNRVEIFFSTDANDLSKIHSILDNEFNPHKQQE
Protein: Myocardin-related transcription factor B (MRTF-B) (MKL/myocardin-like protein 2) (P59759)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Serum response factor
Sequence:
MIDSSKKQPQGFPEILTAEDFEPFKEKECLEGSNQKSLKEVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVVKEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTASTPAQFTSVSPAVPEFLKTPLTADQPPTRSTAPVLPTNTVSSAKSGPMLVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPNQKGEKSEPQMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPIKTDKNSSSGSNSGSSSSMPARRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVTSSNLATGSIVAVSSATIVTSNPEVTVALPVTTLHNAVTSSVSTFKADLALPATSSVPHVENAHSPLPISPSPSEQSSLSTDDTNMTDTFTEIMTMMSPSQLLCSSPLRVVSHDDSLSPSSSTLSTLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQRPPDPQPSDPPHPFNTSDPKHGSVGSSIKDEASLPDCSSPQQPITVPGHSVGQPISTGSQTLVAKKTVVVKQEVPMAQAEQQNVVSQFYLSSQGQPPALVAQPQALLTTQTTQLLLPVSIQGSNVTSVQLPVGSLQLQTPAQGRVQAQPHVAAATQVPAAALPSALTSALPQKQEAFPQHVLGQPQPVRKVFTNSAPNTVLQYQRQPGPTNQQPFVSKTSNPALQSRTAPLAPLQNGPSLASKPSSPPPPQQFVVQHSLFATPITKTKDPPRYEEAIKQTRSTQPALPEVSSVHSQQMDDLFDILIKSGEISFPIKEEPSPISKMKPVTASITTMPVNTVVSRPPPQVQIAPPVSLEPVNSLSASLENQLEAFLDGTLPSATDTGPLQNSSEDRESFSLIEDLQNDLLSHSSMLYQSHSPMETSEAQLVSGTPCLSLDLSDSNLDNMEWLDITMPTTSSGLTPLSTTAPSMFSADFLDPQDLPLPWD
Protein: Phthiocerol/phthiodiolone dimycocerosyl transferase (EC 2.3.1.282) (Acyltransferase PapA5) (Phthiocerol/phthiodiolone O-acyltransferase) (Polyketide synthase-associated protein A5) (P9WIN5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes diesterification of phthiocerol, phthiodiolone, and phenolphthiocerol with mycocerosic acids, the final step in the phthiocerol, phthiodiolone and phenolphthiocerol dimycocerosate esters (PDIM) synthesis. Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (mas) onto the substrate alcohols. Is also able to catalyze acyl transfer using various nucleophiles as acceptors and several acyl-CoA thioesters as donors in vitro; preference is observed for saturated medium chain alcohols and long chain acyl-CoA thioesters.
Interaction partners:
- Phenolphthiocerol/phthiocerol polyketide synthase subunit E
- Doxorubicin resistance ATP-binding protein DrrA
- Doxorubicin resistance ABC transporter permease protein DrrB
- Probable doxorubicin resistance ABC transporter permease protein DrrC
- Phenolphthiocerol/phthiocerol polyketide synthase subunit D
- Long-chain-fatty-acid--AMP ligase FadD26
- Phenolphthiocerol/phthiocerol polyketide synthase subunit A
- Phenolphthiocerol/phthiocerol polyketide synthase subunit C
- Phenolphthiocerol/phthiocerol polyketide synthase subunit B
- Putative phthiocerol dimycocerosate transporter LppX
Sequence:
MFPGSVIRKLSHSEEVFAQYEVFTSMTIQLRGVIDVDALSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDGTAATNGSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVDELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLPQAVPVTRLWLSKQQTSDLMAFGREHRLSLNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLGAASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPPGLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAGQLIIEHHGHIAEPGKSLEAIRSLLCTVPSEYGWIME
Protein: Bromodomain testis-specific protein (Bromodomain-containing female sterile homeotic-like protein) (RING3-like protein) (Q91Y44)
Organism: Mus musculus (Mouse)
Function: Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis. Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time. In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA. Also recognizes and binds a subset of butyrylated histones: able to bind histone H4 butyrylated at 'Lys-8' (H4K8ac), while it is not able to bind H4 butyrylated at 'Lys-5' (H4K5ac). Also acts as a component of the splicing machinery in pachytene spermatocytes and round spermatids and participates in 3'-UTR truncation of specific mRNAs in post-meiotic spermatids. Required for chromocenter organization, a structure comprised of peri-centromeric heterochromatin.
Subcellular location: Nucleus {ECO:0000269|PubMed:17728347, ECO:0000269|PubMed:19794495, ECO:0000269|PubMed:22020252, ECO:0000269|PubMed:32726616}. Note=Detected on chromatin (PubMed:19794495). Excluded from the chromocenter. {ECO:0000269|PubMed:19794495, ECO:0000269|PubMed:22020252}.
Interaction partners:
- Histone H4
- Cyclin-dependent kinase 9
- Cyclin-T1
- Bromodomain-containing protein 2
- Beta-defensin 1
- Bromodomain-containing protein 3
- Bromodomain-containing protein 4
- Histone H3.3
- Histone H3.2
- Histone H3.1
Sequence:
MSLPSRQTAIVNPPPPEYINTKKSGRLTNQLQFLQRVVLKALWKHGFSWPFQQPVDAVKLKLPDYYTIIKTPMDLNTIKKRLENKYYEKASECIEDFNTMFSNCYLYNKTGDDIVVMAQALEKLFMQKLSQMPQEEQVVGGKERIKKDIQQKIAVSSAKEQIPSKAAENVFKRQEIPSGLPDISLSPLNMAQEAPPICDSQSLVQITKGVKRRADTTTPTTSIAKASSESPPTLRETKPVNMPVKENTVKNVLPDSQQQHKVLKTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDADALGLHNYYDVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYNPPDHEVVAMARTLQDVFELHFAKIPDEPIESMHACHLTTNSAQALSRESSSEASSGDASSEDSEDERVQHLAKLQEQLNAVHQQLQVLSQVPLRKLKKKNEKSKRAPKRKKVNNRDENPRKKPKQMKQKEKAKINQPKKKKPLLKSEEEDNAKPMNYDEKRQLSLDINKLPGDKLGRIVHIIQSREPSLRNSNPDEIEIDFETLKASTLRELEKYVLACLRKRSLKPQAKKVVRSKEELHSEKKLELERRLLDVNNQLNCRKRQTKRPAKVEKPPPPPPPPPPPPPPPELASGSRLTDSSSSSGSGSGSSSSSSGSSSSSSSSGSASSSSDSSSSDSSDSEPEIFPKFTGVKQNDLPPKENIKQIQSSVQDITSAEAPLAQQSTAPCGAPGKHSQQMLGCQVTQHLQATENTASVQTQPLSGDCKRVLLGPPVVHTSAESLTVLEPECHAPAQKDIKIKNADSWKSLGKPVKASSVLKSSDELFNQFRKAAIEKEVKARTQEQMRKHLEHNAKDPKVSQENQREPGSGLTLESLSSKVQDKSLEEDQSEQQPPSEAQDVSKLWLLKDRNLAREKEQERRRREAMAGTIDMTLQSDIMTMFENNFD
Protein: B-cell activating factor (A9CDZ0)
Organism: Sus scrofa (Pig)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MYESTGEQSRLSCLSTREEMKMKETVPILPQKESPSVRISKDGKLLVVTLLLALLSCFLTGIFAPPAPRESSSIQSNRSKRAAQDAEETVTQDCLQLIADSDMPTIRKGAYTFVPWLLSFKRGRALGEKENKTVVKETGYFFIYGQVLYTDNTFAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPREDAKISRDGDGTFFGALKLL
Protein: GDSL esterase/lipase At3g14220 (EC 3.1.1.-) (Extracellular lipase At3g14220) (Q9LJP2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Molybdenum cofactor sulfurase family protein
- At1g21440
- 3-isopropylmalate dehydrogenase 3, chloroplastic
- 3-isopropylmalate dehydratase small subunit 2
- Aspartate aminotransferase, cytoplasmic isozyme 2
- Peptide methionine sulfoxide reductase A2
- 3-isopropylmalate dehydrogenase 1, chloroplastic
- N-
- Flavin-containing monooxygenase FMO GS-OX3
- 3-isopropylmalate dehydratase small subunit 3
Sequence:
MAKNRNLVFFLGVLASFTLSSFPVTVSGEPPILFTFGDSSYDVGNTKFFSSEFDPATTWPYGDSIDDPSGRWSDGHIVPDFVGRLIGHREPIPPVLDPKADLSRGASFAIAGAVVLGSQSTTASMNFGQQISKFLELHKQWTDKERAEAIYMVNIGAEDYLNFAKAHPNANTVEQLTQVAHVLQRIPRELTSLYRAGGARKFAVQNLGPLGCLPIVRQEFKTGENCMEMVNFMVKTHNERLSRLLVAITVPLLYRGFRYSLFDFNGEILRRINEPSLHGYTDTTTSCCGTGSRNAYGCGYSNVHAKLCSYQKSFLFFDGRHNTEKTDEEVANLFYSGDKHVVSPMNIKDLVGKAATDLLAQEI
Protein: Kelch-like protein 8 (Q9P2G9)
Organism: Homo sapiens (Human)
Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN.
Interaction partners:
- Cullin-3
- E3 ubiquitin-protein ligase RBX1
- Kelch-like protein 42
- Kelch-like protein 13
- Speckle-type POZ protein
- Speckle-type POZ protein-like
- Kelch-like protein 9
- Ectoderm-neural cortex protein 1
- Kelch-like protein 41
- Kelch repeat and BTB domain-containing protein 6
Sequence:
MASDSMSSKQARNHITKGKRQQQHQQIKNRSSISDGDGEDSFIFEANEAWKDFHGSLLRFYENGELCDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRIDLMDMADQYACDHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLANPQHHSKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDNTCFNDVERYDIESDQWSTVAPMNTPRGGVGSVALVNHVYAVGGNDGMASLSSVERYDPHLDKWIEVKEMGQRRAGNGVSKLHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNRWELVGSVSHCRAGAGVAVCSCLTSQIRDVGHGSNNVVDCM
Protein: Doublecortin domain-containing protein 2B (A2VCK2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGGSPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPSGVIGVYGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISASAPALPS
Protein: Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) (Q9D1E6)
Organism: Mus musculus (Mouse)
Function: Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17217416}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17217416}. Note=Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone. {ECO:0000269|PubMed:17217416}.
Interaction partners:
- Tubulin-specific chaperone D
- Gigaxonin
- Tubulin-specific chaperone A
- Trafficking protein particle complex subunit 4
- Tubulin-specific chaperone E
- Tubulin-specific chaperone C
- ADP-ribosylation factor-like protein 2
- Dynactin subunit 3
Sequence:
MEVTGISAPTVMVFISSSLNSFRSEKRYSRSLTIAEFKCKLELVVGSPASCMELELYGADDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGVRLGEYEDVSKVEKYEISPEAYERRQNTVRSFMKRSKLGPYNEELRAQQEAEAAQRLSEEKAQASAISVGSRCEVRAPDHSLRRGTVMYVGLTDFKPGYWVGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPSAVTVGDFPEEDYGLDEM
Protein: Probable pyridine nucleotide-disulfide oxidoreductase RclA (Reactive chlorine resistance protein A) (P77212)
Organism: Escherichia coli (strain K12)
Function: Probably involved in reactive chlorine species (RCS) stress resistance.
Interaction partners:
- Inner membrane protein RclC
- Uncharacterized protein RclB
- RCS-specific HTH-type transcriptional activator RclR
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex
- Thiol:disulfide interchange protein DsbE
Sequence:
MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCINIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFINNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGHLGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIILNAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVVDKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFMTPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGASLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK
Protein: Integral membrane protein DGCR2/IDD (P98153)
Organism: Homo sapiens (Human)
Function: Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Splicing factor ESS-2 homolog
- Protein HIRA
- Protein DGCR6
- Protein DGCR6L
- Zinc finger protein 74
- Tricarboxylate transport protein, mitochondrial
- Proline dehydrogenase 1, mitochondrial
- Palmitoyltransferase ZDHHC8
- Proline dehydrogenase
- Ubiquitin recognition factor in ER-associated degradation protein 1
Sequence:
MVPKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDPRQGRARGGDPSHFHAVNVAQPVRFSSFLGKCPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPERSFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCAQLQCFHFPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHGGEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGNSLFDSMASGMRLVVSCISSFLILSLLLFMVHRLRQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGEGGTFHFHDPPPPYTAYKYPDIGQPDDPPPPYEASIHPDSVFYDPADDDAFEPVEVSLPAPGDGGSEGALLRRLEQPLPTAGASLADLEDSADSSSALLVPPDPAQSGSTPAAEALPGGGRHSRSSLNTVV
Protein: Universal stress family protein (A0A0E2LMN8)
Organism: Porphyromonas gingivalis F0570
Interaction partners:
Sequence:
MKEEKLVTLAIHSYEKAQILKSLLETEGIEAYLHNVNQIQPVISAGVRVRIKETDLPRALSIIEDNKWDQEDPKKRAKNTEEYVLIPVDFSEYTMKICELGFNFAARRGLRVVLMHVYISPFFSTPLTVGDTAVFQLSNEVSLRKEYQRVQRLMNKLKKELRERITREELPEISFSSVLLDGAPEDVILSYCKRHRPVMIVMGTRGKSRKDSDLIGSVAAEVIDSSKVPVLVIPEEVPFSDLNQAKHVAVATSFDQRDLVLFDAMMKLLDKNNPSYSIFNISVGTPEWNQVQLKAIREYHAHHYPDATINVSMLDEGDFSLALEKFIRQEKVDMIVVNTYRRNFFARFFNPSMARRMLFHAGTPLLVMHN
Protein: Tumor protein p63-regulated gene 1 protein (Protein FAM79B) (Q6ZUI0)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8CB49}.
Interaction partners:
Sequence:
MSTIGSFEGFQAVSLKQEGDDQPSETDHLSMEEEDPMPRQISRQSSVTESTLYPNPYHQPYISRKYFATRPGAIETAMEDLKGHVAETSGETIQGFWLLTKIDHWNNEKERILLVTDKTLLICKYDFIMLSCVQLQRIPLSAVYRICLGKFTFPGMSLDKRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPYATFTEHPMKYTSEKFLEICKLSGFMSKLVPAIQNAHKNSTGSGRGKKLMVLTEPILIETYTGLMSFIGNRNKLGYSLARGSIGF
Protein: Serine-pyruvate aminotransferase (SAT) (EC 2.6.1.51) (Q9X1C0)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Function: Involved in the degradation of L-serine via 3-hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine.
Interaction partners:
- Hydroxypyruvate reductase
- Serine hydroxymethyltransferase
- Threonine dehydratase catabolic
- Tryptophan synthase beta chain 1
- Tryptophan synthase alpha chain
- Phosphoglycerate mutase
- Serine acetyltransferase
- Alanine--tRNA ligase
Sequence:
MGKFLKKHYIMAPGPTPVPNDILTEGAKETIHHRTPQFVSIMEETLESAKYIFQTKHNVYAFASTGTGAMEAAVANLVSPGDKVIVVVAGKFGERWRELCQAYGADIVEIALEWGDAVTPEQIEEALNKNPDAKVVFTTYSETSTGTVIDLEGIARVTKEKDVVLVTDAVSALGAEPLKMDEWGVDLVVTGSQKGLMLPPGLALISLNDKAWGLVEKSRSPRYYFDLRAYRKSYPDNPYTPAVNMIYMLRKALQMIKEEGIENVWERHRILGDATRAAVKALGLELLSKRPGNVVTAVKVPEGIDGKQIPKIMRDKYGVTIAGGQAKLKGKIFRIAHLGYMSPFDTITAISALELTLKELGYEFELGVGVKAAEAVFAKEFIGE
Protein: Putative uncharacterized protein YCL042W (P25572)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Uncharacterized protein YCR024C-B
- Putative pelota-like protein YCL001W-A
- Protein OCA4
- Putative uncharacterized protein YCL068C
Sequence:
MEKKKILDAALAPRIISGVPTDGQPLSGGPLSWAWCHTTLKRWALMKTRPYKYPLSTEPPTPPSVPNSASVNHNTTTNTTLSYTRCHSTTYTKPLRERSSRPWTRSATISRLPPRSWTN
Protein: P30 adhesin (30 kDa adhesin-related protein) (Cytadhesin P30) (P75330)
Organism: Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
Function: Adhesin necessary for successful cytadherence and virulence.
Subcellular location: Cell projection, attachment organelle membrane; Multi-pass membrane protein. Note=Integral and surface exposed membrane protein that localizes to the membrane at the attachment organelle.
Interaction partners:
- Cytadherence high molecular weight protein 3
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS11
- Large ribosomal subunit protein uL16
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS5
Sequence:
MKLPPRRKLKLFLLAWMLVLFSALIVLATLILVQHNNTELTEVKSELSPLNVVLHAEEDTVQIQGKPITEQAWFIPTVAGCFGFSALAIILGLAIGLPIVKRKEKRLLEEKERQEQLAEQLQRISAQQEEQQALEQQAAAEAHAEAEVEPAPQPVPVPPQPQVQINFGPRTGFPPQPGMAPRPGMPPHPGMAPRPGFPPQPGMAPRPGMPPHPGMAPRPGFPPQPGMAPRPGMPPHPGMAPRPGFPPQPGMAPRPGMQPPRPGMPPQPGFPPKR
Protein: DELLA protein RGA (GAI-related sequence) (GRAS family protein 10) (AtGRAS-10) (Repressor on the ga1-3 mutant) (Restoration of growth on ammonia protein 1) (Q9SLH3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenuation of auxin transport delaying its GA-induced degradation. Involved in the regulation of seed dormancy and germination, including glucose-induced delay of seed germination.
Subcellular location: Nucleus {ECO:0000269|PubMed:20093430, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:28412546, ECO:0000269|PubMed:9490740}. Note=Accumulates in the nucleus in response to cold. {ECO:0000269|PubMed:28412546}.
Interaction partners:
- Gibberellin receptor GID1B
- F-box protein GID2
- Transcription factor PIF3
- Gibberellin receptor GID1A
- Gibberellin receptor GID1C
- Transcription factor PIF4
- Protein BRASSINAZOLE-RESISTANT 1
- Transcription factor PIF5
- Transcription factor MYC2
- Gibberellin 3-beta-dioxygenase 1
Sequence:
MKRDHHQFQGRLSNHGTSSSSSSISKDKMMMVKKEEDGGGNMDDELLAVLGYKVRSSEMAEVALKLEQLETMMSNVQEDGLSHLATDTVHYNPSELYSWLDNMLSELNPPPLPASSNGLDPVLPSPEICGFPASDYDLKVIPGNAIYQFPAIDSSSSSNNQNKRLKSCSSPDSMVTSTSTGTQIGGVIGTTVTTTTTTTTAAGESTRSVILVDSQENGVRLVHALMACAEAIQQNNLTLAEALVKQIGCLAVSQAGAMRKVATYFAEALARRIYRLSPPQNQIDHCLSDTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGLQWPALMQALALREGGPPTFRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSDTEAVAVNSVFELHKLLGRPGGIEKVLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGVPNSQDKVMSEVYLGKQICNLVACEGPDRVERHETLSQWGNRFGSSGLAPAHLGSNAFKQASMLLSVFNSGQGYRVEESNGCLMLGWHTRPLITTSAWKLSTAAY