wanglab/gogpt-training-data huggingface dataset:
Protein: Glutamate receptor ionotropic, NMDA 3A (GluN3A) (N-methyl-D-aspartate receptor subtype 3A) (NMDAR3A) (NR3A) (NMDAR-L) (Q8TCU5)
Organism: Homo sapiens (Human)
Function: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. During the development of neural circuits, plays a role in the synaptic refinement period, restricting spine maturation and growth. By competing with GIT1 interaction with ARHGEF7/beta-PIX, may reduce GIT1/ARHGEF7-regulated local activation of RAC1, hence affecting signaling and limiting the maturation and growth of inactive synapses. May also play a role in PPP2CB-NMDAR mediated signaling mechanism.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9R1M7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q13224}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9R1M7}. Postsynaptic density {ECO:0000250|UniProtKB:Q9R1M7}. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. {ECO:0000250|UniProtKB:Q9R1M7}.
Interaction partners:
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2A
- Glutamate receptor ionotropic, NMDA 2B
- Glutamate receptor ionotropic, NMDA 2C
- Glutamate receptor ionotropic, NMDA 2D
- Glutamate receptor ionotropic, NMDA 3B
- Disks large homolog 4
- Proenkephalin-B
- Glutamate receptor 4
- Voltage-dependent calcium channel gamma-2 subunit
Sequence:
MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAPDDSRAGAQRDEPEPGTRRSPAPSPGARWLGSTLHGRGPPGSRKPGEGARAEALWPRDALLFAVDNLNRVEGLLPYNLSLEVVMAIEAGLGDLPLLPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSLVLHIPVISIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTQNNSKFHLGSIINITANLPSTQDLLSFLQIQLESIKNSTPTVVMFGCDMESIRRIFEITTQFGVMPPELRWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEHYVQDAMELVARAVATATMIQPELALIPSTMNCMEVETTNLTSGQYLSRFLANTTFRGLSGSIRVKGSTIVSSENNFFIWNLQHDPMGKPMWTRLGSWQGGKIVMDYGIWPEQAQRHKTHFQHPSKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSTLDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEKIAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLRGTAHMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAVFLTLYEWKSPFGLTPKGRNRSKVFSFSSALNICYALLFGRTVAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVEYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTANISELISQYKSHGFMDMLHDKWYRVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRLHRAINTSFIEEKQQHFKTKRVEKRSNVGPRQLTVWNTSNLSHDNRRKYIFSDEEGQNQLGIRIHQDIPLPPRRRELPALRTTNGKADSLNVSRNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTSRTCES
Protein: Rhomboid domain-containing protein 2 (Rhomboid-like protein 7) (Q8VEK2)
Organism: Mus musculus (Mouse)
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:23386608}; Multi-pass membrane protein {ECO:0000269|PubMed:23386608}.
Interaction partners:
- Rhomboid domain-containing protein 3
Sequence:
MAAPGPASRFWCSCPEVPSATFFTALLSLLVSGPRLFLLQPPLAPSGLSLRSEALRNWQVYRLVTYIFVYENPVSLLCGAIIIWRFAGNFERTVGTVRHCFFTLIFTVFSAIIYLSFESVSSLSKLGEVEDARGFTPVAFAMLGVTSVRSRMRRALVFGVVVPSVLVPWLLLCASWLIPQTSFLSNVSGLLIGLSYGLTYCYSLDLSERVALKLDQKFPFSLMRRIPLFKYISGSSAERRAAQSRRLNPAPGSYPTQSCHPHLTPSYPVTQMQHASGQKLASWPPGHMPSLPPYQPASGLCYVQNHFGPNPNASSVYPASAGTSQGVQPPSPISCPGTVYSGALGTPGATGSKESSKVAMP
Protein: Zinc finger protein ZIC 5 (Odd paired-related protein) (Opa-related protein) (Zinc finger protein of the cerebellum 5) (Q7TQ40)
Organism: Mus musculus (Mouse)
Function: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:15465018}.
Interaction partners:
- Zinc finger protein ZIC 2
Sequence:
MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLVGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQASGQGPCPPSQGLPGLFQVPAPAARSVASGTHPGARTHPDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPALSGYTATNSGGGSSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDGGGSALFPALHDSPGAPGGHPLNGQMRLGLAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAPHPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAGPPASADSGVKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSESEDEEMYGNPEVMRTIH
Protein: Uncharacterized protein (Q641N7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MPTGRTDARTDGRTPQGPAAPATQTRTSRRGQDVHPPRSRCMCHRPSPRWTDGRTHARRQRPPVTAAAHSDVTHESTHVEADAVVKMSLPSPQDGRTDSTRCACRRGRQDGAILTEEGARQQGLTAYRHVPLNKIAVEMEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
Protein: Tetraspanin (A0A0B4KH03)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
Interaction partners:
- FI02253p
Sequence:
MGLNGCCSCVKYLMVLINILFWLIGLTIVVTSVWMLTDPTFMLSMTQNYNHYHIALYVFLAIGILITLGAFFGCCGVCRESQCLLVSFFCVILIVMVAQIAAGAWAFHNKDKLDDIVRAAVKSSVQEEYGQSTMSSRTVTFDTLQKNLKCCGADGPGDWATSRFNNVDRTNIVEIAVSSMNVFYNIPESCCKDNLKDNECELSRRLKFGGPLNNAIYQQGCVDKLIEIIYENWVTIFAVTAAVILLELLSLTFALSLCCAVRNQHYKAXELQNSHREITDDEKY
Protein: Putative lipocalin 1-like protein 1 (Lipocalin 1-like pseudogene 1) (Q5VSP4)
Organism: Homo sapiens (Human)
Function: May bind a variety of ligands including lipids.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MKPLLLAISLSLIAALQAHHLLASDEEIQDVSGTWYLKAMTVDRELPEMNLESVTPMTLTILEGGNLEAKATMLISGQCQEVKVILEKTDEPGKYTANRGKHVAYIIRSHMKDHYIFYCEGRDPENNLEALEDFEKAAGARGLSTESILIPRQSETCSPGSD
Protein: Putative fucose kinase (EC 2.7.1.52) (Q4QEX6)
Organism: Leishmania major
Interaction partners:
- Putative fucose kinase
- Phosphotransferase
- Phosphotransferase
Sequence:
MNVSFLFSLPCNLAEFKGAAKLLADAAALPLRECGAKGGVAVPGLFCGCDPEGRPLGSGGGTVHLLHACYVDEQRHAPASAKRSFLSWLRLADNDGRVIVHAGGLSRRLPAYAAMGKALLPLPPRRWHRGSQLSRTLLSTQVPMYREIVAMAPARLRTLIACGDVCVDARGALPSLAHFADSDVLCFGINADASLLQDYGVLFTARERPLDLDYMLQKPSLDEVRRRVAEGRHSVLLDVGMWMLSDRAVEVLTRKCLGGALDAEDATDGGYDGHRCTAVRTAYDLYSEFASALGNNAPIADPEIAGLKASVVELRDAEFLHYGTNRQLISAVATLQGRESPTPPWSWGTPLDGVLAPERGGGGEELDFAAGDAMPLLATPSSVIVQNSVVLAPLDGSAAAAAADAPAGAPLSPVRHLWVESSWVGARWALRDQHILTGVPRNDWALALPPGACVSVVPVLPAALGGCGDGAVPHAARPYHMDDAFCGDVRSGSTMYMGVRLHDWLSSRGFSVAELYPAARAADGGAAQPLDMYEAALFPVCATEQQLGDFLYVATLPLEAATGGCAGVDAARLAAGQAVWRTQPRVSAMDLLRLTDVPAMLRNSEYYERRMLTLMLALVAGDPAAPRARSPVLPGPMVALLQQQFFLLDLNRVAQRVVELGVPLPRHSGPTEWWGGVDAAGNAVALSRQVAPAAPFAKGAAASAGSWAQVFSDEGSPSGGGRGAPLCTAPGRIVAAHYHAFASRLMELALEAMDAAEPPVSAAEKARRLALLRASSAEEARSLVALHDAAALAELRAAIMDSFPDERHDPEMSVHLDQIIWGRCPIRIDVAGAWTDTPPYAILSGGSVINVAVELNGQPPVQVYVRVREDPIIMMHSIDSGEQLSVSSFDEIRTYATMQNPFSIPKAALALCGFLPEFCATEYATLREQLAARFGGHGLEISLFVAIPTGSGLGTSSIVAGTVLRSLAEFCKLPWDNHDVCRRVLLIEQMLTAGGGWQDQYGGLFEGLKLVQCVPGLPCLPTVRWMPDSVYTDPRFAACHLLYYTGITRMAKGILGEIVRDVLLNNGATLQLLREMGGPTTAAMYDAITTGNYKGYARLVHRTWEQKKRLDDGVCNPTVQSIVDIVEPYVWGLTLPGAGGGGYMYMCAKDEACARRIRELLTANPPNGNARFVEMSVSASGLQISRS
Protein: Oplophorus-luciferin 2-monooxygenase catalytic subunit (19kOLase) (EC 1.13.12.13) (Q9GV45)
Organism: Oplophorus gracilirostris (Luminous shrimp)
Function: Catalytic subunit of oplophorus-luciferin 2-monooxygenase. Oxidoreductase that converts coelenterazine (the oplophorus luciferin) to coelenteramide under emission of blue light with a maximum at 454 nm. Is also active with bisdeoxycoelenterazine.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MAYSTLFIIALTAVVTQASSTQKSNLTFTLADFVGDWQQTAGYNQDQVLEQGGLSSLFQALGVSVTPIQKVVLSGENGLKADIHVIIPYEGLSGFQMGLIEMIFKVVYPVDDHHFKIILHYGTLVIDGVTPNMIDYFGRPYPGIAVFDGKQITVTGTLWNGNKIYDERLINPDGSLLFRVTINGVTGWRLCENILA
Protein: Transcription factor Sox-17-beta.1 (SRY (sex determining region Y)-box 17-beta.1) (Transcription factor Sox-17-beta) (XSox17beta) (O42601)
Organism: Xenopus laevis (African clawed frog)
Function: Transcription activator. Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'. All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in function. In addition, the sox17 proteins have distinct but overlapping roles in later gut development. Acts downstream of vegt-signaling in endoderm differentiation to induce a range of endodermal genes both directly and indirectly. Also represses wnt-responsive genes to inhibit wnt/beta-catenin-mediated signaling.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:9363948}.
Interaction partners:
Sequence:
MSSPDCGYSSDDQIQGSCSVPMMMGQYQWTEPLTVFQDLKPKRDEGSADSRSKAEGRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLATKRPFVEEAERLRVQHIQDYPDYKYRPRRKKQVKRMKREEDGFLPSANFPGSQIMDNNVMVGENYRMQYSAQNHQQNQLPPAGYFEGHNSMGYYYRDYSVPNYHISQNSSGYDSPPAQDEYQALSYSFNSSYMPYQQNATTPVMAKQMAVTQNIPQESPEHGMMASPQMYNRQMYVSECAKTHPMAQTEQHFPSYQSQKTVRQNYLQSQQDGHLESDIDKTEFDQYLMYEPKADMEIIYTIDQDSGAYSTNLLPSLITEANNVCYYDYCGV
Protein: Importin-alpha re-exporter protein, putative (Q587E0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- GTP-binding nuclear protein
- Importin subunit alpha
- Sperm-associated antigen 6
Sequence:
MDPINPNDPILTRRLEMLAQNALSVESADRERAEQEIREFQNRVDIQSGFVLLLLNVASSQSPAASFCSIVFKNTVKNCWNEGTSEHCVAESDKAFVRNNITGIMFSAPLNVQRNLAEAISMIAETDFPSAWPDALQRIIHVLMNEKSVVLHSAALSTAHSILGRYRNQPDLSQETANDLRVIYTDLTSPLLNSMVLLVDAVEKCGTDAHAACTGLTSAVECLRDITAFDLGDEFIWGIEGFVRVLLRCLQLGGSGVLGACTIELKSVVIMCVSHFLLQFDEDFEKYASEFLKVVWDTISSPSSCESDMDDIVVQGMGLLAAACRGATREVFNNESVLVNLMTEVIMPNLALRQVDVELFGTEPDEYIQRDIEGSDFHTRRREAGELVRALLLFFPEKTGPLFTAKAQELLASAAQGDWKAKDLAIYLVSALSLEGQHVSTQRGVTQCLSKLVPFEPFLKQNVLSELSCGVSPQSPAIVKASCIRFVAAFRAHIERSLLPDIIALLASWILCEDTVVQVYAAHAVERVLTLQDPGKPGHVITDTVLGDKAPSLLHNLCVRLNQEKKPIAYTMQCLMRVCQNCSGCVKSFVGDIITCMVPVIKENSKNPSNPLFSHCMFEVVSQCIMLRPEDAAAIESALWEPMIFILQNDVLEYVPYTLQIMAQLLDAHGSGAPEPPTYYQALLEPLLLPEMYKQRGSIPAIVRLLVSFIEHYPGFVHGKGLTERVIAVVRSLVQYKNYDHEGLNILTTMIRAYPKDVISPYMVSIYQSLIQRLQKSRTPKYVRILIIFLSITVITHGADDVVTQINRIQDGLFWMLFQRVWLPHVPKVLGVLERKTCIIALASLLGDCVTLQQNAETWSTCVVSCLKMIHGAVEKDDWTSFTPQTHSVNDLAQHVADIGYTNAFCPLQGAVQTPVDVCPMVQQPEALFRERLQKALSGPNAEQLVRLLQAYPEVMAQLQ
Protein: Female germline-specific tumor suppressor gld-1 (Defective in germ line development protein 1) (Q17339)
Organism: Caenorhabditis elegans
Function: RNA-binding protein which recognizes the 5'-UACUCAU-3' RNA consensus sequence. Binds sequences in both the 5'coding and the 3'-UTR region of rme-2 mRNA. Binds sequences in the 3'-UTR region of cye-1 mRNA. Binds to cyb-2.1, cyb-2.2 and cyb-3 mRNA. Binds sequences in the 3'-UTR region of tra-2 mRNA. Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Represses translation of the vacuolar ATPase component vha-13 in the distal gonad. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation. By regulating cye-1 expression, prevents entry into mitosis in meiotic germline cells.
Interaction partners:
- Defective in germ line development protein 3
- F-box domain-containing protein
- Poly
- Fem-3 mRNA-binding factor 2
- K Homology domain-containing protein
- ATP-dependent RNA helicase cgh-1
- PIP-1
- Protein LSM14 homolog car-1
- RNA-binding protein pos-1
- Fem-3 mRNA-binding factor 1
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
Protein: Large ribosomal subunit protein eL30 (60S ribosomal protein L30) (P62890)
Organism: Rattus norvegicus (Rat)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62888}.
Interaction partners:
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL27
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein uS12
- Large ribosomal subunit protein eL31
Sequence:
MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK
Protein: SH2 domain-containing protein 5 (Q6ZV89)
Organism: Homo sapiens (Human)
Function: May be involved in synaptic plasticity regulation through the control of Rac-GTP levels.
Subcellular location: Postsynaptic density {ECO:0000250|UniProtKB:Q8JZW5}.
Interaction partners:
- Breakpoint cluster region protein
Sequence:
MQKAGAGGRRASDCGLAPHRPRCITKFAQYVGSFPVDDLDTQESVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAEGLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLDMGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG
Protein: Protein PhoH (Phosphate starvation-inducible protein PsiH) (P0A9K1)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm.
Interaction partners:
- Endoribonuclease YbeY
- Nucleoside triphosphate pyrophosphohydrolase
- Protein PsiE
Sequence:
MVTSCTGHVLDNQRATTRGVFSSGSHLVTLHFQPHPFFSCVTDAVNGARSRFSAFYPKANYGLQGSQPSDVRAHNRAANGACDEYKQLKVLSMGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEAIGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHKDVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIGKVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLPRGVCSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS
Protein: Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.10 (O13901)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable ethanolamine-phosphate cytidylyltransferase
- Phosphatidylserine decarboxylase proenzyme 3
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
- Phosphatidylserine decarboxylase proenzyme 2, mitochondrial
- Phosphatidyl-N-methylethanolamine N-methyltransferase
- Phospholipase D1
- Nuclear elongation and deformation protein 1
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Lysophospholipid acyltransferase
- Phosphatidylethanolamine N-methyltransferase
Sequence:
MQLNRKQLKNLHNYKYSAIDNSLLSKYILKPYWWNQLLKVIPMSMAPNLITLIGLGFVVINILTMLVYKYHYEMDAFPSWVYASWAIGLFLYQSFDAIDGSQARRTGTSSPLGQLFDHGVDAINTSFEVLLTIELLQLDMFSSILTQFASLLYFYISTWEEYHTGTLYLSYFSGPVEGIVMVIGLFALTAIKGDSFWLKLHPTPESWGFVRSFLPYYTYGSCLYNFMAFALLLNVLQSLRNALQAVQKNNGSVIKALSGILPYFLQWMAVFSLYAKYPAFFEHHFLTIFCLNAFIFAYSVGVVIVSHITESPFPYWNVLILPFLVDAVDAYTFGVLKNVQTEYFFCYVGICIGVYGNFVAHVIAMITEEYGIKCLTIPSKPESKKN
Protein: Methylesterase 7 (AtMES7) (EC 3.1.1.-) (O80472)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Methylesterase shown to have carboxylesterase activity, methyl indole-3-acetic acid (MeIAA) esterase activity and methyl salicylate (MeSA) esterase activity in vitro. Required to convert methyl salicylate (MeSA) to salicylic acid (SA) as part of the signal transduction pathways that activate systemic acquired resistance in systemic tissue. MeSA is believed to be an inactive form that needs to be demethylated to exert a biological effect.
Interaction partners:
- Pentatricopeptide repeat-containing protein At1g02060
- Transmembrane protein
- Ethylene-responsive transcription factor ERF015
- GTPase ERA-like, chloroplastic
- Octanoyltransferase LIP2p, chloroplastic
- Nucleolar histone methyltransferase-related protein
- Protein kinase superfamily protein
Sequence:
MDKNNQKKFVLVHGICHGAWCWYKVKAQLEAAGHSVTAVDLAASGVNMTSLDEIQTLKDYCKPLLEFLSSLGSDDDKVILVAHSMGGISASLAADIFPSKVAAIVFVAAFMPDISNPPAYVFQKLVKDVTQEVWMDTVFGKPDRPLEFALFGPEFMAKYLYNLSPLQDFELAKMSVRVSPFMTNNLAGTISFSEDRYGSVTRIYIVCGEDVAVPVDYQRGMINDFPVKEVLEIKDADHMPMFSKPQELCALLLEIADKYA
Protein: Talin-1 (Q5U7N6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MVALSLKIGVGNVVKTMQFEPSTVVYDACRIIRERVPEAQLGQPSDYGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTLEYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVRDVGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEESEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKPGFLDLKEFLPKEYVKNKGEKRIFQAHKNCQNMTEIEAKVNYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWAASPKDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQFNKMGKVETGSVALPAIIRSGAGGPESMKMGSMPQAKQHITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAVQASLDEFDALPPLGTDSASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDPAETDYTAVGCAVTTISSNLTEMSKGVKLLAALMEDEGGNGQQLLGAAKNLACAVSDMLKTAQPSSTEPRQNLLQAAGNVGQASGELLQQIGESDADQHFQDMLMQLAKAVANAAAALVLKAKNVAQKSEDSAQQNKVIAAATQCALSTSQLVACTRVVVAPTISSPVCQEQLIEAGKLVAKSVEGCVEASHGATGDEHLLKQVGAAATGVTQALNELLQHIRQYASGGQPIGRHGEATDRILDVTDNIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENSRKLLSAAKLLADATARMVEAAKGAAANPDSEEQQQKLREAAEGLRMATNAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQIPQLVQGLRSSQAQPDSPSAQLALIGASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTAAQKAQEACGPLEIDNALTMVRGLERDMQEAKASAAEGKLRPLPGETLEKCSQDLGSSTKAVSSAIAQLLSEATQGNENYTGMAARDVAQALRSLASAARGVAANTEDPLARNAMLDCTGDVMDKSASLIEETKRAIAKPGDPDSQQRLAQVAKAVSQALNRSVNCLPGQRDVDNAIRTVGEASKKLLSDKFPASGKNFQEAQANLNEAAAGLNQSANELVQASRGTTQDLAKASGKFGQDFNQFLQAGVDMAGQSQSKEDQTQVVTNLKTISMSSSKLLLAAKALSTDPNSPNLKNQLAAAARAVTDSINQLISMCTQQAPGQKECDNALRELETVGGMLENPTEAVNDLGYFDCIDSVMENSKVLGEAMAGISHNAKNSNLPEFGDSVSSASKALCGLTEAAAQGAYLVGVSDPNSHAGQKGLVDPSQFARAKQSIQMACQNLVDPACTQSQVLSAATIVAKHTSALCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKALDGAFNQENRQKCKEATGPLIEAVDNLTAFASNPEFASVPAQISPEGLAAMEPITAAAKAMLESSTGLIQTARSLAVNPKDPPKWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLSNCIREVDKASLAAISQQLTPRDDISHEALHEQMAASVHEISNLIEPVAIAARADASQLGHKVSQMVSYFEPLIMAAIGTASKILNSQQQMNVLDQTKTLAESALQMLYTAKETGGNHKAAHTQEALEESVQMMKEAVDDLGSTLAEVASAAGAVGGMVNSITQSINKMEDGPAFEPEGTFVDYQTTMVKTAKAIAVTVQEMVTKSNTNPDELGGLANQLTTEFGDLASEAKCAAMTAENDEIGSHIKKQVTELGYTCTGLVSKAGALQCSPNDSYTKKELIDSARKVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLNRENAETFADHREHILKTAKVLVEDTKLLVSGAGASQEKLAQAAQSSVNTITKLADVVKLGAASLGSEDPETQVVLINAVKDVAKALGDLISATKAAAGKPHDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATIEHIKQELAVFSSADPPPKTATPEEFIRMTKGITLATAKAVAAGNSCRQEDVIATANLSRRAVADMLRSCKQAAYHPEVKREVQTRALRFGSECSTSYLGLLEHVLVIIQKPSHDLKQQLANYSKRVASSVTELIQAAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAVDDGQWSQGLISAARMVAAATNNLCEAANSAVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSQTMKRLQAAGNAVKRASDNLVKAAQKAAFEAQDDQAVMVKSKMVGGIAQIIAAQEEMLRKEKELEEARKKLAMIRQQQYKFLPSELREDGQEQ
Protein: NUMB-like endocytic adaptor protein (Numb-like protein) (A0A0R4IDU4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Neurogenic locus notch homolog protein 1
- Notch receptor 3.
- Neurogenic locus notch homolog protein 2 precursor
- Notch receptor 1b.
- NUMB endocytic adaptor protein.
- Par-3 family cell polarity regulator alpha, b.
- AP-2 complex subunit alpha
- E3 ubiquitin-protein ligase Mdm2
- Ligand of numb-protein X 2a
- Cyclin G-associated kinase.
Sequence:
MNKLRQSLRRKKPTYVPEASRPHQWQADEEAVRKGKCNFPVRYLGLVEVDESRGMHVCEEAVKKLKVSGKKTVKAVLWVSADGLRVVDDKTKDLIVDQTIEKVSFCAPDRNYDKAFSYICRDGTTRRWMCHCFMALKDSGERLSHAVGCAFAACLERKQRREKECGVTASFDASRTSFVREGSFRVSSAAQQSDREDIMKQIQDKKKEMCGISALPPGNASPPEGAGSPGERAEPGGPHAIPRRHAPIEQLVRQGSFRGFPQLSQKNSPFKRQLSLRLNDLPSTLQRKTDFQTKNPVPEMDLTVAGEADSINALCSQINSSFTKPSEDLCAKTTNNCLPISCAPPAIPPPPAPPQATNLWVQIEPPVQSSPPIPQGGHKRTPSEAERWLEEVAKAVKSQQQTPPTLPPPPTQQPPPVPTMPIAPGSLPTSMQPFPMAFDVTPAPVSMFTQQPLQPAFVPMQPYMPTLANSMTYPNASVPVVGITPSQMVANVFCSAAGTGGGVAIGVGMGPKTGTLGGSQHSAFPTLPGGLPTTTFASPPTINGHPQNSFPSTTTSVTQNGTAVKGGSGWPMENPNPTINSKEAEHFDAKWAALESKSQPKAQNPFSNDLQKTFEIEL
Protein: NADPH-dependent aldehyde reductase ARI1 (EC 1.1.1.-) (P53111)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: NADPH-dependent aldehyde reductase involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion. Reduces commonly detected inhibitors in biomass conversion hydrolysates such as furfural, 5-hydroxymethylfurfural (HMF), cinnamic aldehyde, benzaldehyde, phenylacetaldehyde, and anisaldehyde.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- NADP-dependent alcohol dehydrogenase 6
- Uncharacterized oxidoreductase YDL114W
- Small ribosomal subunit protein uS19
- mRNA decay factor CTH1
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
- NADP-dependent alcohol dehydrogenase 7
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein eS21B
Sequence:
MTTDTTVFVSGATGFIALHIMNDLLKAGYTVIGSGRSQEKNDGLLKKFNNNPKLSMEIVEDIAAPNAFDEVFKKHGKEIKIVLHTASPFHFETTNFEKDLLTPAVNGTKSILEAIKKYAADTVEKVIVTSSTAALVTPTDMNKGDLVITEESWNKDTWDSCQANAVAAYCGSKKFAEKTAWEFLKENKSSVKFTLSTINPGFVFGPQMFADSLKHGINTSSGIVSELIHSKVGGEFYNYCGPFIDVRDVSKAHLVAIEKPECTGQRLVLSEGLFCCQEIVDILNEEFPQLKGKIATGEPATGPSFLEKNSCKFDNSKTKKLLGFQFYNLKDCIVDTAAQMLEVQNEA
Protein: protein-tyrosine-phosphatase (EC 3.1.3.48) (A0A8I6AEM0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MPLTSCRMVPVARLLLLLLAFFLYACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDYRPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGRPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYIFRLSARNKVGFGEEMVKEISVPEEVPTGFPQNLHSEGTTSTSVQISWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPDVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESESRKSSLPNSKEVPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT