wanglab/gogpt-training-data huggingface dataset:
Protein: Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (P10126)
Organism: Mus musculus (Mouse)
Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19856081}. Nucleus {ECO:0000250|UniProtKB:P68104}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P68104}. Cell membrane {ECO:0000250|UniProtKB:P68104}. Note=Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens. Localization at the cell membrane depends on EEF1A1 phosphorylation status and the presence of PPP1R16B. {ECO:0000250|UniProtKB:P68104}.
Interaction partners:
- Elongation factor 1-gamma
- Elongation factor 1-beta
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS3
- Elongation factor 2
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein uL3
- Poly
- Large ribosomal subunit protein uL30
- Small ribosomal subunit protein eS6
Sequence:
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK
Protein: Pollen-specific leucine-rich repeat extensin-like protein 2 (AtPEX2) (Pollen-specific LRR/EXTENSIN2) (Cell wall hydroxyproline-rich glycoprotein) (Q9XIB6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization.
Subcellular location: Secreted, cell wall {ECO:0000250}.
Interaction partners:
- Peroxisome biogenesis factor 10
- Peroxisomal ATPase PEX6
- Peroxisome biogenesis protein 5
- Peroxisome biogenesis protein 7
- Peroxisome biogenesis protein 16
- Protein APEM9
- Peroxisomal membrane protein 13
- Probable purine permease 7
- At1g55535
- Peroxisomal membrane protein 11C
Sequence:
MERPFGCFFILLLISYTVVATFDDEPSFPENADLTKDLEQKCFSINKVDPNLKFENDRLKRAYIALQAWKKAIYSDPFKTTANWVGSDVCSYNGVYCAPALDDDSLTVVAGVDLNHADIAGHLPPELGLMTDLALFHINSNRFCGIIPKSLSKLALMYEFDVSNNRFVGQFPEVSLSWPSLKFLDLRYNEFEGSLPSEIFDKDLDAIFLNNNRFESVIPGTIGKSKASVVTFANNKFSGCIPKSIGNMKNLNEIVFTGNNLTGCFPNEIGLLNNVTVFDASKNGFVGSLPSTLSGLASVEQLDLSHNKLTGFVVDKFCKLPNLDSFKFSYNFFNGEAESCVPGRNNGKQFDDTNNCLQNRPSQKPAKQCLPVVSRPVDCSKDKCSGGSNGGSSPSPNPPRTSEPKPSKPEPVMPKPSDSSKPETPKTPEQPSPKPQPPKHESPKPEEPENKHELPKQKESPKPQPSKPEDSPKPEQPKPEESPKPEQPQIPEPTKPVSPPNEAQGPTPDDPYDASPVKNRRSPPPPKVEDTRVPPPQPPMPSPSPPSPIYSPPPPVHSPPPPVYSSPPPPHVYSPPPPVASPPPPSPPPPVHSPPPPPVFSPPPPVFSPPPPSPVYSPPPPSHSPPPPVYSPPPPTFSPPPTHNTNQPPMGAPTPTQAPTPSSETTQVPTPSSESDQSQILSPVQAPTPVQSSTPSSEPTQVPTPSSSESYQAPNLSPVQAPTPVQAPTTSSETSQVPTPSSESNQSPSQAPTPILEPVHAPTPNSKPVQSPTPSSEPVSSPEQSEEVEAPEPTPVNPSSVPSSSPSTDTSIPPPENNDDDDDGDFVLPPHIGFQYASPPPPMFQGY
Protein: CRISPR-associated endonuclease/helicase Cas3 (EC 3.1.-.-) (EC 3.6.4.-) (P38036)
Organism: Escherichia coli (strain K12)
Function: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity.
Interaction partners:
- CRISPR system Cascade subunit CasC
- CRISPR system Cascade subunit CasD
- CRISPR system Cascade subunit CasA
- CRISPR system Cascade subunit CasE
- CRISPR-associated endoribonuclease Cas2
- CRISPR-associated endonuclease Cas1
- CRISPR system Cascade subunit CasB
- Crossover junction endodeoxyribonuclease RuvC
Sequence:
MEPFKYICHYWGKSSKSLTKGNDIHLLIYHCLDVAAVADCWWDQSVVLQNTFCRNEMLSKQRVKAWLLFFIALHDIGKFDIRFQYKSAESWLKLNPATPSLNGPSTQMCRKFNHGAAGLYWFNQDSLSEQSLGDFFSFFDAAPHPYESWFPWVEAVTGHHGFILHSQDQDKSRWEMPASLASYAAQDKQAREEWISVLEALFLTPAGLSINDIPPDCSSLLAGFCSLADWLGSWTTTNTFLFNEDAPSDINALRTYFQDRQQDASRVLELSGLVSNKRCYEGVHALLDNGYQPRQLQVLVDALPVAPGLTVIEAPTGSGKTETALAYAWKLIDQQIADSVIFALPTQATANAMLTRMEASASHLFSSPNLILAHGNSRFNHLFQSIKSRAITEQGQEEAWVQCCQWLSQSNKKVFLGQIGVCTIDQVLISVLPVKHRFIRGLGIGRSVLIVDEVHAYDTYMNGLLEAVLKAQADVGGSVILLSATLPMKQKQKLLDTYGLHTDPVENNSAYPLINWRGVNGAQRFDLLAHPEQLPPRFSIQPEPICLADMLPDLTMLERMIAAANAGAQVCLICNLVDVAQVCYQRLKELNNTQVDIDLFHARFTLNDRREKENRVISNFGKNGKRNVGRILVATQVVEQSLDVDFDWLITQHCPADLLFQRLGRLHRHHRKYRPAGFEIPVATILLPDGEGYGRHEHIYSNVRVMWRTQQHIEELNGASLFFPDAYRQWLDSIYDDAEMDEPEWVGNGMDKFESAECEKRFKARKVLQWAEEYSLQDNDETILAVTRDGEMSLPLLPYVQTSSGKQLLDGQVYEDLSHEQQYEALALNRVNVPFTWKRSFSEVVDEDGLLWLEGKQNLDGWVWQGNSIVITYTGDEGMTRVIPANPK
Protein: Endo-1,4-beta-xylanase Xyn10A (EC 3.2.1.4) (EC 3.2.1.8) (P84195)
Organism: Gloeophyllum trabeum (Brown rot fungus) (Agaricus trabeus)
Function: Has xylanase, avicelase and cellobiohydrolase activity.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:15870328}.
Interaction partners:
Sequence:
LYMGTATDNGATAMLNLVESLKYSWVPSTFSGQGAATPYDSNLVK
Protein: Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein) (Q9P975)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Interaction partners:
- ATP-dependent RNA helicase eIF4A
- Translation initiation factor eIF4G
- Cap-associated protein CAF20
- Polyadenylate-binding protein, cytoplasmic and nuclear
- Nucleoporin
- Nucleoporin NSP1
- Nuclear cap-binding protein complex subunit 1
- ATP-dependent RNA helicase DED1
- ATP-dependent RNA helicase DHH1
- Tif3p
Sequence:
MSEELAQKTEELSLDSKTVFDSKEEFNAKHPLNSRWTLWYTKPQTNKSENWHDLLKPVITFSSVEEFWGIYNSIPPANQLPLKSDYHLFKEGIRPEWEDEANSKGGKWQFSFNKKSEVNPIINDLWLRGLLAVIGETIEDEENEVNGIVLNIRKQAYRVGIWTKDCDESKLKTVGERLKKVLQLNDEQKVEFMSHDASNTRGAEPQIVL
Protein: Transgelin (Calponin homolog 1) (O14185)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has actin-binding and actin-bundling activity and is a component of the actin patch. Stabilizes actin filaments against disassembly. Cross-links F-actin and is required for the formation of the contractile F-actin ring.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16256112, ECO:0000269|PubMed:16823372}. Note=Localizes to the barrier septum.
Interaction partners:
- Fimbrin
- Alpha-actinin-like protein 1
- Inner kinetochore subunit mis6
- Tubulin beta chain
- Tubulin alpha-2 chain
- Tubulin alpha-1 chain
- Peroxisomal membrane protein pex32
- Nucleoside diphosphate kinase
- Myosin 1 light chain cam2
- Calmodulin
Sequence:
MTSQLEKEAREWIEETLHTKLNAQLDLLDQLQSGVILCRICKEALGANIRYKESNMPFVQMENISAFINYAQQVVHVPSQDMFQTSDLFERRNDEQVLRSIHSFSRYAAKMFPGKVRGLGPKLAEKKPRVFSAQQQREFREGVNSLQYGSFDMPTQGTEKIAFSRRRDPTGNMY
Protein: Pentatricopeptide repeat-containing protein At5g42310, chloroplastic (Protein CRP1 homolog) (AtCRP1) (Q8L844)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for chloroplast protein synthesis and accumulation of subunits of the thylakoid protein complexes. Activates psaC and petA translation by binding their 5'-UTRs. Required for the correct processing of petB and petD mRNAs. Interacts with the petB and petD intergenic region and is required for the generation of petB and petD monocistronic RNAs.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:28261232}. Plastid, chloroplast thylakoid {ECO:0000269|PubMed:28261232}. Plastid, chloroplast {ECO:0000269|PubMed:30962391}.
Interaction partners:
- Protein high chlorophyll fluorescent 107
- Photosystem I iron-sulfur center
- Peptide chain release factor PrfB3, chloroplastic
- Probable LRR receptor-like serine/threonine-protein kinase At2g28960
- Cytochrome b6-f complex subunit 4
- Photosystem II reaction center protein H
- Cytochrome b6
- ATP synthase subunit c, chloroplastic
- Small RNA-binding protein 11
- Ribonuclease III domain-containing protein RNC1, chloroplastic
Sequence:
MLLLQQPPLVSTRFHSLYFLTHHHHHHHRFFQPPISAFSATTSASLPSPSPSSSSSYFSSWNGLDTNEEEDNEFSSEVHRRYDFSPLLKFLSRFGPVELALDSESESEASPESLNPVEFDLVESYRAVPAPYWHSLIKSLTSSTSSLGLAYAVVSWLQKHNLCFSYELLYSILIHALGRSEKLYEAFLLSQKQTLTPLTYNALIGACARNNDIEKALNLIAKMRQDGYQSDFVNYSLVIQSLTRSNKIDSVMLLRLYKEIERDKLELDVQLVNDIIMGFAKSGDPSKALQLLGMAQATGLSAKTATLVSIISALADSGRTLEAEALFEELRQSGIKPRTRAYNALLKGYVKTGPLKDAESMVSEMEKRGVSPDEHTYSLLIDAYVNAGRWESARIVLKEMEAGDVQPNSFVFSRLLAGFRDRGEWQKTFQVLKEMKSIGVKPDRQFYNVVIDTFGKFNCLDHAMTTFDRMLSEGIEPDRVTWNTLIDCHCKHGRHIVAEEMFEAMERRGCLPCATTYNIMINSYGDQERWDDMKRLLGKMKSQGILPNVVTHTTLVDVYGKSGRFNDAIECLEEMKSVGLKPSSTMYNALINAYAQRGLSEQAVNAFRVMTSDGLKPSLLALNSLINAFGEDRRDAEAFAVLQYMKENGVKPDVVTYTTLMKALIRVDKFQKVPVVYEEMIMSGCKPDRKARSMLRSALRYMKQTLRAS
Protein: D-aminoacyl-tRNA deacylase 1 (EC 3.1.1.96) (Gly-tRNA(Ala) deacylase 1) (Gly-tRNA(Gly) deacylase 1) (Q4Q1E7)
Organism: Leishmania major
Function: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs (By similarity). Hydrolyzes correctly charged, achiral, glycyl-tRNA(Gly). Deacylates mischarged D.melanogaster and E.coli glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8IIS0}.
Interaction partners:
- tyrosine--tRNA ligase
- glycine--tRNA ligase
Sequence:
MKAVIQRVLSGSVTSEGEVVGSIQKGLAVLVGIARDDTADDTEYILRKILGVRVWSNEDGSKMWCRNVKEIDGEVLLISQFTLMHVMKGNKPDFHNAMPPEDALKVFNALRDKLRCEYAPHKIATGNFQHYMNIHLSNDGPVTLILDSKKRS
Protein: T-cell surface glycoprotein CD3 epsilon chain (D4A5M2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
- T-cell surface glycoprotein CD3 gamma chain
- T-cell surface glycoprotein CD3 delta chain
- T-cell surface glycoprotein CD3 zeta chain
- Tyrosine-protein kinase
- T-cell surface glycoprotein CD8 alpha chain
- Tyrosine-protein kinase Fyn
- T-cell surface glycoprotein CD4
- Tyrosine-protein kinase
- Proto-oncogene tyrosine-protein kinase LCK
- Receptor-type tyrosine-protein phosphatase C
Sequence:
MQWNAFWSILGLSLLAVGTCQEDIEDTEYEVSISGTSVELTCPLENEDNLKWEKNDKVLPDKNEKHLVLEDFSEVKDSGYYVCYTESSRKNTYLYLKARVCENCMEVDLTAVSIIIIVDICITLGLLMVVYYWSKKRKAKAKPVTRGTGTGGRPRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRAV
Protein: Uncharacterized protein (Q381Z8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MATLQVRDFDPRTATHYYHCILAGIPHPVTLQSISSAIVPDSECESVQNLEKIGCQIVPYRLHVFKETLSLKFGVVDFFIHHSTSGESANPAEVHELFLQWFGSSLTRGVMSLNSWISLGQPRELHSATPFVSALMEKCSFFDAKVVSDIEKLRTFILSKVRFDNRGLNAHANNRSRVAASEDSSLQEEQTRTDCGNDPSVEWKSVGTLSASSLDSQELAWLSRQHRQFPSIAPANEREASATWELEPVRTFLQKALTPLVEVVK
Protein: Transcription factor SOX-5 (P35711)
Organism: Homo sapiens (Human)
Function: Transcription factor involved in chondrocytes differentiation and cartilage formation. Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes, such as COL2A1 and AGC1. Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate. Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes. Together with SOX6, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts. Binds to the proximal promoter region of the myelin protein MPZ gene.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P35710}.
Interaction partners:
- Transcription factor SOX-6
- Transcription factor SOX-9
- Ethanolamine kinase 1
- Catenin beta-1
- Collagen alpha-1
- Transcription factor SOX-13
- Centrosomal protein of 85 kDa
- Transcription factor 7
- Fez family zinc finger protein 2
- Transcription factor SOX-11
Sequence:
MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN
Protein: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (TbMTr1) (Q38AH0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of spliced leader and U1 small nuclear RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped RNA to produce m(7)GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. Recognizes a guanosine cap on RNA independent of its N(7) methylation status.
Subcellular location: Nucleus {ECO:0000269|PubMed:17606627}.
Interaction partners:
- mRNA
Sequence:
MPAVADCTVVFPLRHDPASTHPDVSGLVGKAFERVNWRDAFDTFLAEERSALWAAKTAFDNTDTSAYIAARDALFPQAVSGVHGAVAFRNRAGHKLHETMEAVGLWEYLKGGATRAKGTFTFVDVCGGPGAFSQALFAMGKEHKLRLRGFGLTLRNVKGLDWYTDLPSRSFFPCYGIDGTGDVFKLENIESLCSLTCKENVRLVVADGGFDVPTEVVNFQETISCRIVYGQWLSAVKLLRPGGCFVLKLFDCFSPFTRAILFLTTHLYESVQVVKPRHSRVVNSERYLVCIGFIGAPKQWLEHFERCYQEGFVDNDNIPTVLPTSLFSGDKIFGADVERMSATIASNQVSGLHAILEKLQSKPAMEEVKS
Protein: Protein DSE1 (Daughter-specific expression protein 1) (Q59Y20)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Involved in cell wall metabolism and required for the separation of the mother and daughter cells.
Interaction partners:
- Ribosome biogenesis protein ERB1
- Pescadillo homolog
- Ribosome biogenesis protein YTM1
- Nucleolar GTP-binding protein 2
- Ribosome assembly factor mrt4
- Ribosome biogenesis protein NOP53
- Chitinase 3
- Utp13p
- mRNA-binding ribosome synthesis protein
- Pre-rRNA-processing protein IPI3
Sequence:
MTDYYEPTFLFRQNAIKRFSPSLSPISSVESLSLVDSNSISNNGTTTTTTTTTSSIYQNASNSSWLLNPYNVKDTAILNQSCCLNRTNVKSNYWKIPDESMNLTSMSINKNQGGNPILAISSGKSESNLFIYELNLFNNHLIHHHTISLPNIHAMKWINNTRYLVTGNNKGYAHLVSTPKLATHDVFNTNSNGDFDYNDDDEDDNNSAEICKRFNHRKHLKQNQLENTISTPIKHLNFLNNHENLLSIYNDYLFYWDIKGCHQQTRPSPISISTVSGIKNFDVPEKNHSSTNTSSANTVAICGLFGVSLFDLRDCQFNIPNYNTAQIHDKTQSSYRKLSANIVKWNPMNTNILAAGHGDGVIRLWDIRKQDSYIAELYGHNNYSITTSMEWNNNDLFTGSKDGNIIHWDLSNISKDSQWEENDNTKLPISCGLKEGFNSIEFNGKANKLETKLDQYQCGTILPASNSSIVAMCSTTTTTSSNDHDDEEIKILSIDSSSFLGVHNKVSESINVNINTNKLYYTEEDIQLLLQSQLNNNNITSSSATGSNDTLISFGNNVSQDSLVKPLTISRKPTTTIKNNNNNTTTRPTNTHTHSASIDESIVSVHNVSNDTLVNSPTRFNICESEDEFTFNYVKNNTNNEDQRQSDNRNSSFSSVSSQQTQLNNSVESLSTVVTDVENEVNHQEHKYMSLLLPVKDTSTTTTTTKDNNTNSDQAVTNTPIISI
Protein: Sperm protein associated with the nucleus on the X chromosome N2 (Nuclear-associated protein SPAN-Xn2) (SPANX-N2) (SPANX family member N2) (Q5MJ10)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEQPTSSTNGEKRKSPCESNNKKNDEMQEAPNRVLAPKQSLQKTKTIEYLTIIVYYYRKHTKINSNQLEKDQSRENSINPVQEEEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDPPEGSSQEDEDLDSSEGSSQEGGED
Protein: L71-8 (Q24076)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKLTLCFLVILGCVIVHGQSPDCKEIKDICSKCIQRLNDPYNKVDFINKGCRNRVRGSYVWKDQNLCELQAIRCSAPNRAMNCVVIADVAKMRRVTPRPPG
Protein: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG (RPnTP synthase subunit PhnG) (EC 2.7.8.37) (P16685)
Organism: Escherichia coli (strain K12)
Function: Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate.
Interaction partners:
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
- Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL
- Putative phosphonates utilization ATP-binding protein PhnK
- Probable transcriptional regulator PhnF
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI
- Ribose 1,5-bisphosphate phosphokinase PhnN
- Phosphonates import ATP-binding protein PhnC
- Phosphonates-binding periplasmic protein
Sequence:
MHADTATRQHWMSVLAHSQPAELAARLNALNITADYEVIRAAETGLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVQGRDKQHAERCALIDALMQQSRHFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA
Protein: Glucokinase (EC 2.7.1.2) (Glucose kinase) (B1VZT1)
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235)
Interaction partners:
Sequence:
MGLTIGVDIGGTKIAAGVVDEEGRILSTFKVATPPTAEGIVDAICAAVAGASEGHDVEAVGIGAAGYVDDKRATVLFAPNIDWRHEPLKDKVEQRVGLPVVVENDANAAAWGEYRFGAGQGHDDVICITLGTGLGGGIIIGNKLRRGRFGVAAEFGHIRVVPDGLLCGCGSQGCWEQYASGRALVRYAKQRANATPENAAVLLGLGDGSVDGIEGKHISEAARQGDPVAVDSFRELARWAGAGLADLASLFDPSAFIVGGGVSDEGELVLDPIRKSFRRWLIGGEWRPHAQVLAAQLGGKAGLVGAADLARQG
Protein: Glycogen debranching enzyme (TreX) (EC 3.2.1.-) (Q7LX99)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Interaction partners:
- Maltooligosyltrehalose synthase
- Glucan phosphorylase, putative
- Malto-oligosyltrehalose trehalohydrolase
- Glycogen synthase
- Ornithine carbamoyltransferase
- Alpha amylase
Sequence:
MALFFRTRDRPLRPGDPYPLGSNWIEDDDGVNFSLFSENAEKVELLLYSLTNQKYPKEIIEVKNKTGDIWHVFVPGLRPGQLYAYRVYGPYKPELGLRFNPNKVLIDPYAKAINGSVIWNDAVFGYKIGDQNQDLTYDERDSGEYVPKSVVINPYFEWDDEDFIKGKKVPLKDTVIYEVHVKGFTKLRLDLPENIRGTYEGLASEQMISYLKDLGITTVELMPVFHFIDQRFLTDKGLTNYWGYDPINFFSPECRYSSTGCLGGQVLSFKKMVNELHNAGIEVIIDVVYNHTAEGNHLGPTLSFRGIDNTAYYMLQPDNKRYYLDFTGTGNTLNLSHPRVIQMVLDSLRYWVTEMHVDGFRFDLAAALARELYSVNMLNTFFIALQQDPILSQVKLIAEPWDVGQGGYQVGNFPYQWAEWNGKYRDSIRRFWRGEALPYSEIANRLLGSPDIYLGNNKTPFASINYVTSHDGFTLEDLVSYNQKHNEANGFNNQDGMNENYSWNCGAEGPTNDQNVVICREKQKRNFMITLLVSQGTPMILGGDELSRTQRGNNNAFCQDNEITWFDWNLDERKSKFLEFVKKMIQFYRAHPAFRRERYFQGKKLFGMPLKDVTFYTLEGREVDEKTWSSPTQLVIFVLEGSVMDEINMYGERIADDSFLIILNANPNNVKVKFPKGKWELVISSYLREIKPEERIIEGEKELEIEGRTALVYRRIEL
Protein: 4-hydroxyphenylacetate 3-monooxygenase oxygenase component (HPA 3-monooxygenase oxygenase component) (EC 1.14.14.9) (p-hydroxyphenylacetate 3-hydroxylase large component) (HPAH large component) (Q9HWT7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3-hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN. In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde.
Interaction partners:
- 4-hydroxyphenylacetate 3-monooxygenase reductase component
- Homoprotocatechuate 2,3-dioxygenase
- 5-carboxymethyl-2-hydroxymuconate isomerase
Sequence:
MKPEDFRASATRPFTGEEYLASLRDDREIYIYGDRVKDVTSHPAFRNAAASMARLYDALHDPQSKEKLCWETDTGNGGYTHKFFRYARSADELRQQRDAIAEWSRLTYGWMGRTPDYKAAFGSALGANPGFYGRFEDNAKTWYKRIQEACLYLNHAIVNPPIDRDKPVDQVKDVFISVDEEVDGGIVVSGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTPGMKLICRPSYELVAGIAGSPFDYPLSSRFDENDAILVMDKVFIPWENVLIYRDFERCKQWFPQGGFGRLFPMQGCTRLAVKLDFITGALYKALQCTGSLEFRGVQAQVGEVVAWRNLFWSLTDAMYGNASEWHGGAFLPSAEALQAYRVLAPQAYPEIKKTIEQVVASGLIYLPSGVRDLHNPQLDKYLSTYCRGSGGMGHRERIKILKLLWDAIGSEFGGRHELYEINYAGSQDEIRMQALRQAIGSGAMKGMLGMVEQCMGDYDENGWTVPHLHNPDDINVLDRIRQ
Protein: Protein phosphatase 1 regulatory subunit 35 (Q9D8C8)
Organism: Mus musculus (Mouse)
Function: During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with TTTN, leading to the centriole to centrosome conversion (By similarity). In addition may play a role in the primary cilia assembly.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8TAP8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q8TAP8}. Note=Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel. Co-localizes with RTTN at the centriole. {ECO:0000250|UniProtKB:Q8TAP8}.
Interaction partners:
- Rotatin
Sequence:
MMGFGASALESIEGEEALEVPGPPPEPRAPEPRAPEPEPGLDLSLSPSPLPESPKARKSSPGQRKGRRGGSRRGRQVRFQLAPPSPVRSEPLLVAGAPGDDHELEAPALQSSLALSLELQNARAAVASGQFDASKAVEEQLRKSFRTRCALEETVAEGLNVPRSKRLYRDLVSLQVPEEQVLNAALREKLAMLPPQPRAPPLKEVLGPGPDMTMLCNPDSLWSESPHLTVDGLPPLRLQARPRPSEDTFLMHRMLRRWEA
Protein: Autophagy-related 18b, isoform A (Autophagy-related 18b, isoform B) (GH07816p) (Q9VIE1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Autophagy-related protein 2
- Autophagy-related 16, isoform F
- Autophagy-related 1, isoform B
- Autophagy-related protein 9
- Autophagy protein 12-like
- Autophagy protein 5
- Autophagy-related 8a, isoform A
- Cysteine protease
- Autophagy-related 8b, isoform A
- Ubiquitin-like modifier-activating enzyme ATG7
Sequence:
MTTYQMNFNQDFTSLSVLSPTGLRLFSISSQDKVEEIFAKDNTEQIRIVERLFNSSLVVLVTAQKPNCLKMLHFKKKQDICNCFYPSEILCVRMNRQRLIVCLAESIHIHDIRDMKILHSIENIAPNEQGLCALSLNSHLAFPVCQTSGELRIFNASKLRTGMTIRAHDTSLSALAFSPSGALLATASERGTVIRVFCVKNGQRVQEFRRGVSCVRIASLVFSASGDFLCASSNTETVHVFKIDTRAVETVELKAIADVAAKSENSAKEAVASTAAEESCRPVASWGGMFSKAVSSLLLPTQVSEVLAQDRSFATVQLAQGGLKHICALTRVQKEPRLLIACEDGFLYVHEFPAERGGPCKLMSVHDLRGALEDVIELELSESVQRSQTKPSNPSTVTQPSLTMLKSCAASVLIENPDPMQDNSYASILKGDQADAMSDSAKFRKLCDAIDTPTKLYDERQFPPVAITAKD
Protein: Yellow fluorescent protein (YFP) (P21578)
Organism: Aliivibrio fischeri (Vibrio fischeri)
Function: Antenna protein that modulates the color of the bioluminescence emission of the luciferase. In the presence of YFP and only at temperatures below 20 degrees Celsius, luciferase exhibits a bimodal emission spectrum with a new peak at 545 nM (yellow), in addition to the one at 485 nM.
Interaction partners:
Sequence:
MFKGIVEGIGIIEKIDIYTDLDKYAIRFPENMLNGIKKESSIMFNGCFLTVTSVNSNIVWFDIFEKEARKLDTFREYKVGDRVNLGTFPKFGAASGGHILSARISCVASIIEIIENEDYQQMWIQIPENFTEFLIDKDYIAVDGISLTIDTIKNNQFFISLPLKIAQNTNMKWRKKGDKVNVELSNKINANQCW