wanglab/gogpt-training-data huggingface dataset:
Protein: Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2) (Q9WTW1)
Organism: Rattus norvegicus (Rat)
Function: May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
Subcellular location: [Isoform 1]: Cell membrane. Postsynaptic density. Note=Isoform 1 was found in synaptic plasma membrane and postsynaptic density.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Membrane; Peripheral membrane protein. Synapse. Note=Isoform 2 was found at excitatory synapses and also at non-synaptic membranes and within intracellular compartments.; SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane. Postsynaptic density. Cell projection, dendritic spine. Endoplasmic reticulum. Cytoplasm, cytoskeleton. Note=Isoform 3 was found in synaptic plasma membrane and postsynaptic density. Isoform 3 was also found in dendrites where it was associated with microtubules, endoplasmic reticulum and dendritic spines.; SUBCELLULAR LOCATION: [Isoform 4]: Membrane; Peripheral membrane protein. Note=Isoform 4 was exclusively membrane associated. {ECO:0000269|PubMed:11978826}.
Interaction partners:
- Glutamate receptor 2
- PRKCA-binding protein
- Glutamate receptor 3
- Nuclear receptor-interacting protein 2.
- Glutamate receptor 1
- GRIP1-associated protein 1
- Zinc finger protein 668
Sequence:
MLAVSLKWRLGVVRRRPKDDGPYSKGGKDTAGTDGALVCRRQSIPEEFRGITMVELIKREGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIRLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGAHEDLHKSRPLVLTYVRPGGPADREGSLKVGDRLLSIDGIPLHGASHATAIATLQQCSHEALFQVEYDVATPDTVANASGPLVVEIAKTPGSALGISLTTGSHRNKPAITIDRIKPASVVDRSGALHAGDHILAIDGTSTEHCSLVEATKLLASVTEKVRLEILPAPQSRRPLKPPEAVRIQRSEQLHHWDPCVPSCHSPRPSHCRAPTWAPGGQDQSRSVSSTPFSSPTMNPAFPCANASTLPRGPMSPRTTAGRRRQRRKEHRSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALARKVVLEIEFDVAESVIPSSGTFHVKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDHCPMEYAVQILRQCEDLVKLKIRKDEDNSDEQESSGAVSYTVELKRYGGPLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRQSGSLSEASDVDEDPPEALKGGLLTTHFSPAVPSVDSAVESWGSSATEGGFGGSGSYTPQVAVRSVTPQEWRSSRLKSSPPPLEPRRTSYTPGPTDESFPEEEEGDWEPPMSPAPGPAREEGFWRVLGEALEDLESCGQSELLRELEASIMTGTVQSVAVDGRPGSRPWRRSREVGTSPEDLQELLLPTPLEMHRVTLHKDPVRNDFGFSVSDGLLEKGVYVHTVRIDGPAQHGGLQPFDRLLQVNHVRTRDFDCCLAVPLLAEAGDILELVVSRNPLAQSRRTPGAPGPSSPQMI
Protein: Large ribosomal subunit protein bL31 (50S ribosomal protein L31) (P0A7M9)
Organism: Escherichia coli (strain K12)
Function: Binds the 23S rRNA.
Interaction partners:
- Elongation factor Tu 1
- GTP pyrophosphokinase
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL10
- Large ribosomal subunit protein bL28
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein bL33
- Small ribosomal subunit protein uS15
- Large ribosomal subunit protein bL27
- Small ribosomal subunit protein bS20
Sequence:
MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRDVATGGRVDRFNKRFNIPGSK
Protein: tRNA pseudouridine synthase B (EC 5.4.99.25) (tRNA pseudouridine(55) synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase) (Q97QJ3)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
Interaction partners:
Sequence:
MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVLPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDEAIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAEKVEAGQLDFLHPLEIGTGDLVKVFLSPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKRGNLYKPRKVFS
Protein: GH14032p (Yuri gagarin, isoform I) (Q7K540)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASRQAGFVLDAKSMGLNPSRPASSPPPPPSSASQMCRQVQPTGTSASHPHQESTLKASSPDRCTASTEAMSTEHYRCLIQKLRDTNGDAGDMSFELNSIFLKRLDEIDCLDEHEGDDMHTCQLRLVTFQEWVDFLLHVNSVILGNVSDLEKEAYSKIVACCQSVQVRQQHTLEENRRLREDICAIIERVQHSPHCTDFDFNGISLETLTVNQLRGVGKDPAHAECESEKVGHRSLKGKGGGDSNVKWDPKSSHKRENSK
Protein: Transcription factor HRS1 (MYB-domain transcription factor HRS1) (NIGT1 protein homolog) (AtNIGT1) (Protein HYPERSENSITIVITY TO LOW PI-ELICITED PRIMARY ROOT SHORTENING 1) (Q9FX67)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor involved in nitrate and phosphate signaling in roots. Integrates nitrate and phosphate starvation responses and adaptation of root architecture depending on nutrient availabilities. Acts downstream of the nitrate sensor and transporter NPF6.3/NRT1.1. Represses primary root development in response to phosphate deficiency conditions, only when nitrate is present. Involved in the modulation of primary root and root hair growth in phosphate-deprived environement. May be required for suppressing abscisic acid (ABA) signaling in germinating embryo axis, which promotes the timely germination of seeds.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:25723764}.
Interaction partners:
- Protein NRT1/ PTR FAMILY 6.3
- LOB domain-containing protein 37
- Inorganic phosphate transporter 1-1
- Protein NLP6
- High-affinity nitrate transporter 2.1
- SPX domain-containing protein 4
- Protein NLP7
- High affinity nitrate transporter 2.4
- High affinity nitrate transporter
- Expressed protein
Sequence:
MIKKFSNMDYNQKRERCGQYIEALEEERRKIHVFQRELPLCLDLVTQAIEACKRELPEMTTENMYGQPECSEQTTGECGPVLEQFLTIKDSSTSNEEEDEEFDDEHGNHDPDNDSEDKNTKSDWLKSVQLWNQPDHPLLPKEERLQQETMTRDESMRKDPMVNGGEGRKREAEKDGGGGRKQRRCWSSQLHRRFLNALQHLGGPHVATPKQIREFMKVDGLTNDEVKSHLQKYRLHTRRPRQTVPNNGNSQTQHFVVVGGLWVPQSDYSTGKTTGGATTSSTTTTTGIYGTMAAPPPPQWPSHSNYRPSIIVDEGSGSHSEGVVVRCSSPAMSSSTRNHYVKNN
Protein: 60S ribosomal protein L13a, putative (Q585J5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 60S ribosomal protein L27a
- 40S ribosomal protein S13, putative
- 60S ribosomal protein L35, putative
- 40S ribosomal protein S25
- 60S ribosomal protein L28, putative
- 60S ribosomal protein L17, putative
- 60S ribosomal protein L37a, putative
- 40S ribosomal protein S33, putative
- 60S acidic ribosomal protein P0
- 40S ribosomal protein S14
Sequence:
MVLPSRRSLNRSSRKGFKKHRPDIIVIDLKDHVLGRAAAIVAKQLLLGKKITVVRCEKLTIAGSEIRNKIKYLQFLRKRKLSNPKLGPFHHRSPSDVFIRTVRSMLPRYTKRGQRALRQLVAYEGVPVNVVRTGGRVVIPKAQRHNCYRNERRFTVLGNMCKHVGWKYSDVVEKLEAARIEKSGRHHKKMEKVRVAWKNARKEALKKMPQKNVEVLKKFGLA
Protein: Always early (Q2PNP0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRHQLKKPRKMVAAWQNDELFIKRPNFAPRIRISEKPEIQGRIKPGVASKRTENFTKKPSNISVDVSEDEKAKEKEKEQDPYSNDFILGKRLYNFLKYLSSHRWIWCEFVDSFLDKPTLTMGYDMKRFIAEYCPLLHSCFMPRRGWQLVRRNMGKARRFSAAFIELEREELECQRRIVRQLQQHKFNPKENVGYLDQIPKRVPLPLAKDATVSSFLHGKSFEGIVNGTVMGYDPQDYTYLVRFNRNDNAVVLSLPDSQLYSDEETAAVPLSIIMRGNKSSSVISESAKTEKFGNKRYTKELLESVLRVGKLQDVKHKILMDLARMNEDFETFKEIGSSSSRRDAKVTPQRENLQRRYSASMITLHRVNADILEPLRILHDYLVEYQKQDEEEESKRGRPASEVYQKCRMQAEQDLKTAADEKFLKIESDRTQEFVRNLHTILYLNGKLGRENSSNLETIIADLVTHMVDNIQPSLGRKLKDGVDSLEPLRQQVVQIFKDVKKPERFQITQQAPMQTEDGIYNFVVEAQPDTPS
Protein: Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (Telokin) (G1U9Q7)
Organism: Meleagris gallopavo (Wild turkey)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGDVKLVTSTRVSKTSLTLSPSVPAEAPAFTLPPRNIRVQLGATARFEGKVRGYPEPQITWYRNGHPLPEGDHYVVDHSIRGIFSLVVKGVQEGDSGKYTCEAANDGGVRQVTVELTVEGNSLKKYSLPSSAKTPGGRLSVPPVELRPSIWGESPPKFATKPNRVVVREGQTGKFSCKITGRPQPQVTWSKGDIHLQQNERFNMFEKTGIHYLEIQNVQLADAGIYTCMVVNSAGKASVSAELTVQGPDKTDTHAQPICMPPKPTMLATKAIENSDFKQATSNGIAKELKSSSTELMVETKDRVSAKKETFYISREAKDVKQGQNQEANVAPLQESRGTKAPQVLQKTSSTITLQAVKVQPEPKAEPQTTFIRQAEDRKRTVQPLMTTQENPSLTGQASPRSREAENRAGARKTVKEEKREPLGIPPQFESCPQNLEASEGQEIKFKSKVSGKPKPDVEWFKEGAPIKTGEGVQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWFLTVKRSKVEEVAPCFSSVLKGCTVSEGQDFVLQCCVGGVPVPEITWLLNEQPIQYAHSTFEAGVAKLTVQDALPEDDGIYTCLAENTTGRASCSAQVTVKEKKSSKKAESAQAVKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPGTGCEILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGECSCQVSLMLRESSASRAEMLRDGRESASSGERRDGGNHGALTFDRTSGFKKSSGETRAAEEEQEDVRGVLKRRVETREHTEESLRQQEAEQLDFRDILGKKVSTKSFSEEDLKEIPAEQMDFRANLQRQVKPKTLSEEERKVHAPQQVDFRSVLAKKGTPKTPLPEKVPPPKPAVTDFRSVLGAKKKPPAENGSASTPAPNARAGSEAQNATPNSEAPAPKPLVKKEEKNDRKCEHGCAVVDGGIIGKKAENKPAASKPTPPQSKGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPATVTWTLDNKVIKSSKSIVISQEGTLCSLIIEKVMPEDRGEYKCIAENAAGKAECVCKVLVEDTSSTKAAKLAEKKTKKPKTTLPPVLSAESSEATVKKKPAPKTPPKAATPPQITQFPEDRKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKLTISSTKQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFNVQDLQVDREYKFRVRAANVYGISEPSQESEVVKVGEKQEEELKEEEAELSDDEGKETEVNYRTVTINTEQKVSDVYNIEERLGSGKFGQVFRLVEKKTGKVWAGKFFKAYSAKEKENIRDEISIMNCLHHPKLVQCVDAFEEKANIVMVLEMVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTSIKLIDFGLARRLESAGSLKVLFGTPEFVAPEVINYEPIGYETDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKSRLNCTQCLQHPWLQKDTKNMEAKKLSKDRMKKYMARRKWQKTGHAVRAIGRLSSMAMISGMSGRKASGSSPTSPINADKVENEDAFLEEVAEEKPHVKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWFKDDQPVKESRHFQIDYDEEGNCSLTISEVCGDDDAKYTCKAVNSLGEATCTAELLVETMDKEKEEGEGEEDEEEEEE
Protein: ATP synthase peripheral stalk subunit OSCP, mitochondrial (ATP synthase subunit O) (Oligomycin sensitivity conferral protein) (OSCP) (Q54RA8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity).
Subcellular location: Mitochondrion. Mitochondrion inner membrane {ECO:0000250}.
Interaction partners:
- ATP synthase F
- ATP synthase subunit 9, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase subunit a
- ATP synthase F
- ATP synthase subunit alpha
- V-type proton ATPase proteolipid subunit
- V-ATPase proteolipid subunit C-like domain-containing protein
- Centrosomal protein 148 kDa
Sequence:
MLARFSRTAIKSGRYFSTSAKNTAPVSEAEEIEILKAVEAPQFKDAVKKTRQQYQDMISKLTNDESGKSITQSTGLRPTINISTPSGKIAHALFDAASSMRSVGIVAKELTQVKTIIDKTPGLKTALEGDIDNSEKTVMLELLQGSVTLSPVSGFFLYYMTYENNFKLINPALTDFKRLVGSLDTEMSIKLTVAHQYSEAEKKDLETNVKSFFPPETQFKFSYNVDPEIQKGYIIESPFINHDASYSTAVKKVKAQEQSVLAEFLNDIKNGIKNQTAVWETKEFRDKYLTLDESKN
Protein: Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Hematopoietic protein-tyrosine phosphatase) (HEPTP) (Protein-tyrosine phosphatase LC-PTP) (P35236)
Organism: Homo sapiens (Human)
Function: Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14613483}. Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 14
- Dual specificity protein phosphatase 3
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 11
- Mitogen-activated protein kinase 13
- Tyrosine-protein phosphatase non-receptor type 5
- 6-pyruvoyl tetrahydrobiopterin synthase
- Mitogen-activated protein kinase 8
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
Protein: AT2G47900 protein (Tubby like protein 3) (C0Z2Z7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSFKSLIQDMRGELGSISRKGFDVRFGYGRSRSQRVVQDTSVPVDAFKQSCWASMPPELLRDVLMRIEQSEDTWPSRKNVVSCAGVCRNWREIVKEIVRVPELSSKLTFPISLKQPGPRGSLVQCYIMRNRSNQTYYLYLGLNQAAASNDDGKFLLAAKRFRRPTCTDYIISLNCDDVSRGSNTYIGKLRSNFLGTKFTVYDAQPTNPGTQVTRTRSSRLLSLKQVSPRIPSGNYPVAHISYELNVLGSRGPRRMQCVMDAIPASAVEPGGTAPTQTELVHSNLDSFPSFSFFRSKSIRAESLPSGPSSAAQKEGLLVLKNKAPRWHEQLQCWCLNFNGRVTVASVKNFQLVAAPENGPAGPEHENVILQFGKVGKDVFTMDYQYPISAFQAFTICLSSFDTKIACE
Protein: Penicillin-binding protein 1 (Q7D529)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MPERLPAAITVLKLAGCCLLASVVATALTFPFAGGLGLMSNRASEVVANGSAQLLEGQVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTMKLAIVSIEDKRFADHSGVDWKGTLTGLAGYASGDLDTRGGSTLEQQYVKNYQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKSEILTRYLNLVSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSTLNPYTNPDGALARRNVVLDTMIENLPGEAEALRAAKAEPLGVLPQPNELPRGCIAAGDRAFFCDYVQEYLSRAGISKEQVATGGYLIRTTLDPEVQAPVKAAIDKYASPNLAGISSVMSVIKPGKDAHKVLAMASNRKYGLDLEAGETMRPQPFSLVGDGAGSIFKIFTTAAALDMGMGINAQLDVPPRFQAKGLGSGGAKGCPKETWCVVNAGNYRGSMNVTDALATSPNTAFAKLISQVGVGRAVDMAIKLGLRSYANPGTARDYNPDSNESLADFVKRQNLGSFTLGPIELNALELSNVAATLASGGVWCPPNPIDQLIDRNGNEVAVTTETCDQVVPAGLANTLANAMSKDAVGSGTAAGSAGAAGWDLPMSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDSSSPTDLCSGPLRHCGSGDLYGGNEPSRTWFAAMKPIANNFGEVQLPPTDPRYVDGAPGSRVPSVAGLDVDAARQRLKDAGFQVADQTNSVNSSAKYGEVVGTSPSGQTIPGSIVTIQISNGIPPAPPPPPLPEDGGPPPPVGSQVVEIPGLPPITIPLLAPPPPAPPP
Protein: Pup deamidase/depupylase (EC 3.4.-.-) (EC 3.5.1.119) (Deamidase of protein Pup) (P9WNU9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Specifically catalyzes the deamidation of the C-terminal glutamine of the prokaryotic ubiquitin-like protein Pup to glutamate, thereby rendering Pup competent for conjugation. Also displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; is thus involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins.
Interaction partners:
- Proteasome subunit alpha
- Proteasome subunit beta
- Prokaryotic ubiquitin-like protein Pup
- Proteasome-associated ATPase
- Putative glutamate--cysteine ligase 2
- Conserved protein
- Bacterial proteasome activator
- Pup--protein ligase
- Protein PafB
Sequence:
MQRIIGTEVEYGISSPSDPTANPILTSTQAVLAYAAAAGIQRAKRTRWDYEVESPLRDARGFDLSRSAGPPPVVDADEVGAANMILTNGARLYVDHAHPEYSAPECTDPLDAVIWDKAGERVMEAAARHVASVPGAAKLQLYKNNVDGKGASYGSHENYLMSRQTPFSAIITGLTPFLVSRQVVTGSGRVGIGPSGDEPGFQLSQRSDYIEVEVGLETTLKRGIINTRDEPHADADRYRRLHVIIGDANLAETSTYLKLGTTALVLDLIEEGPAHAIDLTDLALARPVHAVHAISRDPSLRATVALADGRELTGLALQRIYLDRVAKLVDSRDPDPRAADIVETWAHVLDQLERDPMDCAELLDWPAKLRLLDGFRQRENLSWSAPRLHLVDLQYSDVRLDKGLYNRLVARGSMKRLVTEHQVLSAVENPPTDTRAYFRGECLRRFGADIAAASWDSVIFDLGGDSLVRIPTLEPLRGSKAHVGALLDSVDSAVELVEQLTAEPR
Protein: Liver X receptor (B8Y3M1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MSTLSATDITDVGPGEVFDGAPELQLDCFCSGDGRSSAEMKHEGNLLPLEPPDHAGFSSSPQKRPSSLAEESSPLPMEPSDIKADPAGSMPANTEGQPVKRKKGPAPKMLGNEVCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKSAQYSCKNNGRCEMDMYMRRKCQQCRLRKCREAGMLEQCVLSEEQIRVKKMKKNEEETARTSAVVTPTPVPEVVPLAPEQLEMIEKLVAMRKQCNKRSFIDRPKVTPWPQSQDPQNREVRQQRFAHFTELAIMSVQEIVDFAKQLPGFLELTREDQIALLKTSTIEIMLLETSRRYNPAIESITFLKDFSYNKEDFAKAGLQLEFINPIFEFSKGMNDLHLDEAEYALLIAINIFSADRPNVQDHELVERLQQPYVDALRSYIMIKRPNDHLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Protein: UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (O07248)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- UTP--glucose-1-phosphate uridylyltransferase
- UDP-glucose 4-epimerase
- Possible dTDP-glucose 4,6-dehydratase
- Glucose-1-phosphate thymidylyltransferase
- Uncharacterized protein Rv0501
- dTDP-4-dehydrorhamnose 3,5-epimerase
- Uncharacterized protein Rv1510
- UDP-galactopyranose mutase
- Deacetylase
- Possible dTDP-glucose 4,6-dehydratase
Sequence:
MRCSVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGDIPFYEPGLRKLLTDNLAAGRLRFTTDYDMAADFADVHFLGVGTPQKIGEYGADLRHVHAVIDALVPRLVRASILVGKSTVPVGTAAELGHRAGALAPRGVDVEIAWNPEFLREGFAVHDTLNPDRIVLGVQDDSTRAEVAVRELYAPLLAAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSQLADALGYDPRIGRQCLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRTKMVELATTACGGSLLGANIAVLGAAFKPESDDVRDSPALNVAGQLQLNGATVHVYDPKALDNAHRLFPTLNYAVSVAEACERADAVLVLTEWREFIDLEPADLANRVRARVIVDGRNCLDVTRWRRAGWRVFRLGVPRLGH
Protein: Coiled-coil domain-containing protein 50 (Protein Ymer) (Q810U5)
Organism: Mus musculus (Mouse)
Function: Involved in EGFR signaling.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17503326}. Note=Associated with microtubules of the cytoskeleton and mitotic apparatus.
Interaction partners:
Sequence:
MADVSVDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNIQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKALEQHDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKRRKKHTPEFSGGSVFGDNYYHEDGGMKPRGIKEAVSTPARASHRDQEWYDAEIARKLQEEELLATHVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKHDPECKLKAKSAHSKSKEGDEAHRSKIDRPSRPPPPTMMGLEDTDPTHFTNQHSTTWHLPKSESSQKGFHNKQ
Protein: Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA p14 subunit) (TFIIA-14) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma) (dTFIIA-S) (P52656)
Organism: Drosophila melanogaster (Fruit fly)
Function: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. Part of a rhi-dependent transcription machinery that enables the generation of piRNA precursors from heterochromatin while maintaining the suppression of transposon-encoded promoters and enhancers. Forms a complex with Moonshiner/CG12721 and Trf2 which recruit transcriptional machinery to heterochromatin to initiate the bidirectional transcription of piRNA clusters, by interacting with the RDC (rhi, del and cuff) complex that binds to repressive H3K9me3 marks in the chromatin. This mechanism allows transcription to occur in piRNA clusters despite the lack of proper promoter elements and in the presence of the repressive H3K9me3 mark.
Subcellular location: Nucleus.
Interaction partners:
- Transcription initiation factor IIA subunit 1
- Transcription initiation factor IIE subunit beta
- General transcription factor IIE subunit 1
- Transcription initiation factor IIB
- TATA-box-binding protein
- General transcription factor IIF subunit 1
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
Sequence:
MSYQLYRNTTLGNTLQESLDELIQYGQITPGLAFKVLLQFDKSINNALNQRVKARVTFKAGKLNTYRFCDNVWTLMLNDVEFREVHEIVKVDKVKIVACDGKSGEF
Protein: Malate synthase (EC 2.3.3.9) (Q9LZC3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Does not seem to be essential for lipid utilization and gluconeogenesis in seedlings.
Subcellular location: Glyoxysome {ECO:0000305}.
Interaction partners:
- Isocitrate lyase
- Citrate synthase 5, mitochondrial
- Citrate synthase 1, peroxisomal
- Citrate synthase 4, mitochondrial
- Citrate synthase 2, peroxisomal
- Citrate synthase 3, peroxisomal
- Malate dehydrogenase 1, peroxisomal
- Malate dehydrogenase 2, peroxisomal
- Malate dehydrogenase 2, mitochondrial
- Malate dehydrogenase 3, cytoplasmic
Sequence:
MELETSVYRPNVAVYDSPDGVEVRGRYDQIFAKILTREALSFVAELQREFRGHVKYAMECRREARRRYNSGAVPGFDPSTKFIRDGDWSCASVPPAVADRRVEITGPVERKMIINALNSGAKVFMADFEDALSPSWENLMRGHVNLKDAVDGSITFHDKSRNRVYKLNDQTAKLFVRPRGWHLPEAHILIDGEPATGCLVDFGLYFFHNYAKFRQTQGSGFGPFFYLPKMEHSREAKIWNSVFERAEKMAGIERGSIRATVLIETLPAVFQMNEILYELRDHSVGLNCGRWDYIFSYVKTFQAHPDRLLPDRVLVGMGQHFMRSYSDLLIRTCHKRGVHAMGGMAAQIPIRDDPKANEMALDLVRKDKLREVRAGHDGTWAAHPGLIPICMEAFTGHMGKSPNQIKSVKREDAAAITEEDLLQIPRGVRTLEGLRLNTRVGIQYLAAWLTGSGSVPLYNLMEDAATAEISRVQNWQWIRYGVELDGDGLGVRVSKELFGRVVEEEMERIEKEVGKDKFKNGMYKEACKMFTKQCTAPELDDFLTLAVYNHIVAHYPINVSRL
Protein: Doublesex and mab-3 related transcription factor 3 (F6W2R2)
Organism: Equus caballus (Horse)
Function: Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within a specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
Interaction partners:
Sequence:
MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAAAAAPQPPPTSQPSQPPPPQRPAAELAAAAALRWATEPQPGALQAQLAKPDLTEERLGDGSSADNTETFSDKDTDQRSSPDVVKSKGCFTPESPEVVSVDEGGYAVQKNGGTSESRPDSPKYHGEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSASAADRTSAEPESLVLPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPNPLAVPLQHPFPQPPRYPLMLRNTLARNQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPGSSPSVFRSSPVLPTRAPEDPRISIPDDGCPIVSKQSLYTEDDYDERSDSSDSRILNTSS
Protein: PvdP (Q9I188)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- PvdO
- PvdN
- Acyl-homoserine lactone acylase PvdQ
- Pyoverdine biosynthesis protein PvdE
- PvdJ
- L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH
- PvdG
- Pyoverdine synthetase D
- PvdL
- L-ornithine N
Sequence:
MTVSRRGFMAGLALTGAAALPVAYYTHRHLTREEEPQTPDEASLDLAATDGIRLGDRLRGLWDLRLVGGDAELPGLPREGLQLVLDVAPKGRGLIGYLDTPERLLAAEPPRFRVLGDLLGASSASIRWRLVDQASGSVAPTHDCSAVFDEVWADYANAGDGTLSGRIQRLERSPLSPNEDFRFVAVKRHFPLAHERIVLNEKLLGWLVSPQHRLFHQLWHASRDKWHRLSEKQRNALRGVGWQPGPLDRERDARGPRKDRNASGIDFFFMHRHMLHTARSMQDLPSWERLPRPVVPLEYDRPGFIRYFDNPDGFSVPPAWVAVDDDEYSEWLHGLKSAEAYHANFLVWESQYQDPAYLAKLTLGQFGSELELGMHDWLHMRWASVTRDPSNGAPVMTDRFPADFAPRWFRPENDFLGDPFSSHVNPVFWSFHGWIDDRIEDWYRAHERFHPGEVQRREVEGIQWFAPGRWVEVGDPWLGPATHGCGLSDVQASSNSVELDVETMKLALRIIFSEEDQLSGWLKRAPRRPWYARNLKLARDQLRR
Protein: KDEL-tailed cysteine endopeptidase CEP3 (EC 3.4.22.-) (Q9STL5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the final stage of developmental programmed cell death and in intercalation of new cells. Cleaves extensins, thus probably supporting the final cell collapse.
Subcellular location: Endoplasmic reticulum {ECO:0000255|PROSITE-ProRule:PRU10138}.
Interaction partners:
- UPF0235 protein At5g63440
- Precursor of CEP1
Sequence:
MKLFFIVLISFLSLLQASKGFDFDEKELETEENVWKLYERWRGHHSVSRASHEAIKRFNVFRHNVLHVHRTNKKNKPYKLKINRFADITHHEFRSSYAGSNVKHHRMLRGPKRGSGGFMYENVTRVPSSVDWREKGAVTEVKNQQDCGSCWAFSTVAAVEGINKIRTNKLVSLSEQELVDCDTEENQGCAGGLMEPAFEFIKNNGGIKTEETYPYDSSDVQFCRANSIGGETVTIDGHEHVPENDEEELLKAVAHQPVSVAIDAGSSDFQLYSEGVFIGECGTQLNHGVVIVGYGETKNGTKYWIVRNSWGPEWGEGGYVRIERGISENEGRCGIAMEASYPTKLSSTPSTHESVVRDDVKDEL
Protein: Butyrate--CoA ligase AAE11, peroxisomal (EC 6.2.1.2) (Acyl-activating enzyme 11) (Butyryl-CoA synthetase) (Q9C8D4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Butyrate--CoA ligase that is active in vitro with medium-chain fatty acids, with a preference for hexanoate and octanoate.
Subcellular location: Peroxisome {ECO:0000305}.
Interaction partners:
- Cytochrome P450 71B31
- S-
- Cytochrome P450 71B38
- Putative acyl-activating enzyme 19
- Acyl-CoA
- At4g10300
- Putative cysteine-rich repeat secretory protein 13
Sequence:
MDNLVLCEANNVPLTPITFLKRASECYPNRTSIIYGQTRFTWPQTYDRCCRLAASLLSLNITRNDVVSILAPNVPAMYEMHFSVPMTGAVLNPINTRLDAKTIAIILRHAEPKILFVDYEFAPLIQEVLRLIPTYQSQPHPRIILINEIDSTTKPFSKELDYEGLIRKGEPTPSSSASMFRVHNEHDPISLNYTSGTTADPKGVVISHQGAYLSALSSIIGWEMGIFPVYLWTLPMFHCNGWTHTWSVAARGGTNVCIRHVTAPEIYKNIELHGVTHMSCVPTVFRFLLEGSRTDQSPKSSPVQVLTGGSSPPAVLIKKVEQLGFHVMHGYGLTEATGPVLFCEWQDEWNKLPEHQQIELQQRQGVRNLTLADVDVKNTKTLESVPRDGKTMGEIVIKGSSLMKGYLKNPKATSEAFKHGWLNTGDIGVIHPDGYVEIKDRSKDIIISGGENISSIEVEKVLYMYQEVLEAAVVAMPHPLWGETPCAFVVLKKGEEGLVTSEGDLIKYCRENMPHFMCPKKVVFFQELPKNSNGKILKSKLRDIAKALVVREDDAGSKKVHQRSIEHVSSRL