wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial sulfonylurea-receptor) (MITOSUR) (Q9CXJ4)
Organism: Mus musculus (Mouse)
Function: ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (By similarity). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (By similarity). Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9NUT2}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
- Mitochondrial potassium channel
- Iron-sulfur clusters transporter ABCB7, mitochondrial
Sequence:
MLVHLFRFGIRGGPVPGWSLQSLRFQTFSAARSSDDRLSSHLLRTVAQLRVQLRAHLPRAPPASHWSPSAWCWVGGTLVVPAVLWQHPRLCLIALCEAKESPPAQPTRAPELRFNWKLFWHFLHPHLLALGAAIVLALGAALVNVQIPLLLGQLVEIVAKYTRDHMGSFVSESRKLSVQLLLLYGVQGLLTFGYLVLLSHIGERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVIGSLVSLSMLSPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGVADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALSPVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPPAEKPEDPKSCQSKA
Protein: Afadin- and alpha-actinin-binding protein A (ADIP-A) (Afadin DIL domain-interacting protein A) (SSX2-interacting protein A) (XSSX2IP) (Q6NRK1)
Organism: Xenopus laevis (African clawed frog)
Function: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Involved in cell movement (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome.
Subcellular location: Cell junction, adherens junction {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:23816619}.
Interaction partners:
Sequence:
MGDRRTISLPESDKILQYCSEIRMSPTSLLPSPSHSVANNLSGSVYTFCTEDNLEQCITYIDQELRTIGFPTVQAVSKNGEGRKLHLVSIINCIYELLQRNSQTMRSNEEVETQLLKINGDLEYLQSIHQRQKDQLEATKRENCALQERDRQMQCKNRNLLQLLKNEKEEVQKLQNIIASRSTQYNHSVKRKEREYNKLKERLYQLVMDKRDKKISIDVLNYVGRADGKRSSWRTGKTDAKNEEEMYKVLLNDYEQRQKQLMVENVELKKVLQQMKKEMISIVSQRKTKEKLEDSTGTVTSDIEEEIADSSKENLSELSCEAVREQLISSIRQQWRILKSHMEKLDNQACLVNVPTPDENGLIARAEHEQELDKLISEIQQCKETIRSQQQLLKQQLSVPRDDDTSKLLQDCYLLEDKERLQEEWKLFNAQKKNFEKERRNFTEAAIRLGHEKKVFEEDRAAWLKHQFLNMTVFSDHKNLEERKVPGVHFSSEQDNCRLHSRPHDKVLASSGDYSRRPSKALPITSSSKHSLTQIESISWRDSSISPNDTDFLN
Protein: Glutamate decarboxylase B (EC 4.1.1.15) (Q54IJ3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Generates GABA from glutamate. Likely to be responsible for the metabolism of glutamate via the GABA shunt to succinate during growth.
Interaction partners:
- 4-aminobutyrate aminotransferase
- Glutamate dehydrogenase 2
- Glutamate dehydrogenase, mitochondrial
- Pantoate--beta-alanine ligase
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
- Aldehyde dehydrogenase family 3 comG
- Aldehyde dehydrogenase
- Aldehyde dehydrogenase
- Putative aldehyde dehydrogenase family 7 member A1 homolog
- Cysteine dioxygenase
Sequence:
MPLHIVDKHKSLYDNYVQSATTEEIAKFKLADDPNEPETIKKLIMDELLLDGNSKQNLATFCQTDLDKNIHSIMDKCIDKNMIDKDEYPQSAEIENRCLHILADLWNAPDSSDTIGCSTTGSSEAAMLGGLALKWNWRENRKKLGLPYDKPNIVTGPVQICWHKFALYFDIEIREIPMENGRYVMNSEEVLKRVDENTIGVIPTLGVTFTLQYEDVFSISNALDKFEKESGINIPIHVDAASGGFVAPFIQQEIIWDFRLPRVKSINASGHKFGLSPLGVGWVVWREKKDLHKDLVFNVNYLGGNMSTFSLNFSRPGGQIIAQYYNFLRHGRNGYTLIQDACAQQGIFIGKELKKMGIFDLIYDGTGALPGVCWTISKNLPSEPLFNLYDLSEKLRSRGWQVASYSLPSSMNDVVVSRVVIRHGFSRDLSSLFVKDVQNAIEYFQKHPILRSLEKDEGENFHH
Protein: Growth-regulating factor 7 (AtGRF7) (Transcription activator GRF7) (Q9FJB8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU01002}.
Interaction partners:
- Dehydration-responsive element-binding protein 2A
- GRF1-interacting factor 1
- 14-3-3-like protein GF14 psi
Sequence:
MDFLKVSDKTTIPYRSDSLFSLNQQQYKESSFGFRDMEIHPHPTPYAGNGLLGCYYYYPFTNAQLKELERQAMIYKYMIASIPVPFDLLVSSPSSASPCNNKNIAGDLEPGRCRRTDGKKWRCAKEVVSNHKYCEKHLHRGRPRSRKHVEPPYSRPNNNGGSVKNRDLKKLPQKLSSSSIKDKTLEPMEVSSSISNYRDSRGSEKFTVLATTEQENKYLNFIDVWSDGVRSSEKQSTTSTPVSSSNGNLSLYSLDLSMGGNNLMGQDEMGLIQMGLGVIGSGSEDHHGYGPYGVTSSLEEMSSWLAPMSTTPGGPLAEILRPSTNLAISGDIESYSLMETPTPSSSPSRVMKKMTSSVSDESSQV
Protein: Photosystem II reaction center protein L (PSII-L) (P0C416)
Organism: Oryza sativa (Rice)
Function: One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01317}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01317}.
Interaction partners:
Sequence:
MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
Protein: Dct1 (D2Y3F6)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFIVE
Protein: Protein Thf1 (P73956)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: May be involved in photosynthetic membrane biogenesis.
Interaction partners:
- Photosystem II CP47 reaction center protein
- Photosystem II reaction center Psb28 protein
- Photosystem II extrinsic protein O
- Sll1390 protein
- Photosystem II lipoprotein Psb27
- Photosystem I reaction center subunit II
- Photosystem I reaction center subunit III
- Photosystem I reaction center subunit XI
- Sll1252 protein
- Photosystem II extrinsic protein U
Sequence:
MTKIRTVSDAKRKFFTHYSRPISSIYRRFVEELLVEMHLLSVNIDFTYDPIFALGIVTSFNSFMQGYQPAEQLPAIFNALCHGVDQNPDQVRQDAKNVAASAHHIGLDAWVTAAASEQASGDNLLLNTLTGIHQRHKFKYSRLFAIGLYTLLADQDPEVKDNDEKRQDYLTRLSELLDLSLDKVVKDLDLYRSNLEKVDQLLKVLEDAAEAERKKKEKQAASTTPAIEEAPVTTAESSES
Protein: DNA ligase (EC 6.5.1.1) (A0A0G2JV76)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTLAFKTLFPRNLCALGRKELCLFSEQHHWPAIRQFSQWSETNLLCGCCLLQRRKPVLSFQRGHLRPRATHLISWSGSHVGLCTGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQISQHIADLSSKTAATPKKKATVQAKLTTTGQVTSPVKGASFITSTNPRKFSGFSAAKPNNSEQDPSSPAPKTSLSASKCDPKHKDCLLREFRKLCAMVAENPSYNTKTQIIHDFLQKGSTGDGFRGDVYLTVKLLLPGVIKSVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDAFLLHLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNEQEVEKDPGRRRALSVQASLMTPVQPMLAEACKSIEYAMKKCPNGMFSEIKYDGERVQVHKKGDHFSYFSRSLKPVLPHKVAHFKDYIPKAFPGGQSMILDSEVLLIDNNTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIRNRIMFSEMKQVTKASDLADMINRVIREGLEGLVLKDVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPDSQKWCTVTKCAGGHDDATLARLQKELDMVKISKDPSKIPSWLKINKIYYPDFIVPDPKKAAVWEITGAEFSRSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKDKADFAVVAGDEGSSTTGGSNGENEGTAGSTVPRKGPKGPPSKSSASAKKTEQKLNDPSSRGGNTLIPKLSPMKPGEKLAVKSSPVKVGMKRKAADETPGLTKALLDVFTGVRLYLPPSTPDFRRLKRYFVAFNGDLVQEFDMASATHVLGNRDKNTDAQLVSSEWIWACIRKRRLVAPC
Protein: Voltage-dependent T-type calcium channel subunit alpha (Q7Z003)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}.
Interaction partners:
- Voltage-dependent L-type calcium channel subunit alpha
- Guanylate kinase/L-type calcium channel beta subunit domain-containing protein
- VWFA domain-containing protein
- Voltage-dependent calcium channel unc-36
- Caveolin-2
- Voltage-dependent calcium channel type A subunit alpha-1
- SH3 domain-containing protein
- Ryanodine receptor
- Degenerin-like protein unc-105
- Caveolin-1
Sequence:
MLRQPVPELRSFQSLSKYAGGPRSVLGRRTSAITVNRRQSQSTRRHEDVEALGSIEGSKETLQLSEHGRLASSSEASPSRWEGRQIEWGNEEQIEEESELPYPGFAEPALRCFYQARPPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVINLPKTISENQSALFNNVKLTRFYIPEDTSLEYICSQPDANGLHTCSNLPPYTVDGVKCNLTLDEYDKVTNDSCINWNIYYNECQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRETERMLQERKMLLNRDSISCTGSEIGGASSKEEGDTVYAAFVRFIGHTFRRTKRAAKKKYTAYMEERAERKSSERQQRRKSKLDDMATLSRIEEKAEDEEDETTITRENGDDQIEQNGDGVRIKRVKIEEEPKIKIGNGNSNGPHYKHSSSDEESDEDGEEDQVYDGEEAKKKSTPSKLWWFREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQEGKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKKCERKNFDTLLWALITVTLGMVLFGCKFCNHPDTGLQCTSAQVISSICECDRMNFDNFLFATVTVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARKQAVEEEDERKRELELIIAKTTSPAFNNGVAPAECTCQRPSSPEESPSPRLLSANYHPSPERKHSANLDAIIDKRLVLRNSAPFDRSPVSEGRDDSRLNRHASLVLPVANGVPYRRQRVHSWSGLCHHFNPNCPVHGRRALIETYAREKFLEASQELKQALAEEEKRNEAKQNTFVRKLLKKTCLHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKEKEKRLKRKLKRQKFEESMAGKRKKMERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDALRDDCDSSDHCETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKHLEESNKRDAEGPAEPTGENIENEITKSDDDEIVEEHEPLAIEHVKEGELDEEEETEEGPTTQIPDGHGGIKRLSMQVLEQELIEVERHLEERYRRASECLGGELQPLNPGEIEDLDDPEFRPRSRSHRPRARTNSALSNKSRGSHKSAL
Protein: U3 small nucleolar RNA-associated protein 5 (U3 snoRNA-associated protein 5) (U three protein 5) (U3 protein 5 required for transcription) (t-UTP5) (Q04177)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12068309, ECO:0000269|PubMed:15489292}. Note=Associated with ribosomal chromatin, even in the absence of transcription.
Interaction partners:
- U3 small nucleolar RNA-associated protein 20
- U3 small nucleolar RNA-associated protein 6
- rRNA-processing protein UTP23
- Essential nuclear protein 1
- Ribosomal RNA-processing protein 9
- Nucleolar protein 58
- KRR1 small subunit processome component
- U3 small nucleolar RNA-associated protein 8
- rRNA-processing protein FCF1
- Ribosome biogenesis protein ENP2
Sequence:
MDSPVLQSAYDPSGQYLCYVTVALDKQRVGVQPTQRATSSGVDTVWNENFLYLEDSKLKVTCLKWVNLASSDTVAIILGMNNGEIWLYSVLANEVTYKFTTGNSYEIKDIDLMGNQLWCIDSSDAFYQFDLLQFKLLQHFRINNCVQLNKLTIVPAGDSVAQLLVASHSISLIDIEEKKVVMTFPGHVSPVSTLQVITNEFFISGAEGDRFLNVYDIHSGMTKCVLVAESDIKELSHSGQADSIAVTTEDGSLEIFVDPLVSSSTKKRGNKSKKSSKKIQIVSKDGRKVPIYNAFINKDLLNVSWLQNATMPYFKNLQWREIPNEYTVEISLNWNNKNKSADRDLHGKDLASATNYVEGNARVTSGDNFKHVDDAIKSWERELTSLEQEQAKPPQANELLTETFGDKLESSTVARISGKKTNLKGSNLKTATTTGTVTVILSQALQSNDHSLLETVLNNRDERVIRDTIFRLKPALAVILLERLAERIARQTHRQGPLNVWVKWCLIIHGGYLVSIPNLMSTLSSLHSTLKRRSDLLPRLLALDARLDCTINKFKTLNYEAGDIHSSEPVVEEDEDDVEYNEELDDAGLIEDGEESYGSEEEEEGDSDNEEEQKHTSSKQDGRLETEQSDGEEEAGYSDVEME
Protein: FAD synthetase 1, chloroplastic (EC 2.7.7.2) (AtRibF1) (FAD pyrophosphorylase 1) (FMN adenylyltransferase 1) (Flavin adenine dinucleotide synthase 1) (Q9FMW8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:18713732}.
Interaction partners:
- Bifunctional riboflavin kinase/FMN phosphatase
- Nudix hydrolase 23, chloroplastic
- 6,7-dimethyl-8-ribityllumazine synthase, chloroplastic
- Flavin mononucleotide hydrolase 1, chloroplatic
- FAD synthetase 2, chloroplastic
- Purple acid phosphatase 8
- Purple acid phosphatase 7
- Purple acid phosphatase 4
- Purple acid phosphatase 3
- Purple acid phosphatase 17
Sequence:
MLCGGSRASVHLWDHRHPPRLGAKVLRKSSFMLRPCSAISQQRIKSSFRSHCKTPRKIPAPLDCFSQGDDHPELSAEGLSPVAGGIVALGKFDALHIGHRELAIQAARIGTPYLLSFVGLAEVLGWKPRAPIVAKCDRKRVLSSWASYCGNIAPVEFEIEFASVRHLNPQQFVEKLSRELRVCGVVAGENYRFGYRASGDASELVRLCKDFGISAYIINSVMDKNQVSVNTEEEDSKSKERGQVSSTRVRHALAAGDVRYVTELLGRPHRVISRTRTQDLTSKRGRISLQTSSLLNLPPGNGVYKACSLIVGDKHPISCKVIVDTSNLYIETEEERFHNSDESQEFQLLGIEFG
Protein: Dethiobiotin synthetase (DTB synthetase) (EC 6.3.3.3) (Dethiobiotin synthase) (DTBS) (P53630)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Dethiobiotin synthetase involved in the biotin biosynthesis pathway.
Interaction partners:
- Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
- Biotin synthase, mitochondrial
- 7-keto 8-aminopelargonic acid transporter
- Uncharacterized protein YJR154W
- Vitamin H transporter
- Biotin--protein ligase
- Serine palmitoyltransferase 2
- 5-aminolevulinate synthase, mitochondrial
- Serine palmitoyltransferase 1
- Putative aryl-alcohol dehydrogenase AAD10
Sequence:
MNSKSQQQEQQPIVFVTGTDTDVGKTFVSTLLVHKWKAAYWKPVQTGIESDQGDSETLKNFKIAASTWQPPIFTPTYALQKPLSPLQAMEYEPNVDIRLLDFVVPEEWSAENPLVVEGAGGVCVPITRKLEITTDLIKHLIETSGHPVYVVVVARSGLGTLNHTLLTWNHLCDNGLRSHLFGVILNGEPNEGNVQALKKFGVNIMAQVAQCTTAHDQDMELHELPSVESLMTQQDVE
Protein: Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29) (Q8N8R3)
Organism: Homo sapiens (Human)
Function: Mitochondrial transporter of arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mechanisms. Plays a physiolocical role in the import of basic amino acids into mitochondria for mitochondrial protein synthesis and amino acid degradation.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:19287344}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Mitochondrial carnitine/acylcarnitine carrier protein
Sequence:
MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQPSSL
Protein: Ofr1p (Q5A784)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Uncharacterized protein
Sequence:
MNKLTLRSLRSLNQNRLFSNSLRKMSTEYNVIIYDFPNSDRSKVRPQHVADIPANVPNPIRSAGAIYQDEAKTKFAGSAFHLVANSKEEVIEFLKKDIYYREGIWDINSVVINPIGVAVRLPKKMDGVDESNYKI
Protein: Cartilage-associated protein (Q9CYD3)
Organism: Mus musculus (Mouse)
Function: Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- Prolyl 3-hydroxylase 1
- Peptidyl-prolyl cis-trans isomerase B
- Serpin H1
- Collagen alpha-2
- Collagen alpha-1
- Peptidyl-prolyl cis-trans isomerase FKBP10
- Trimeric intracellular cation channel type B
- Protein disulfide-isomerase
- Collagen alpha-2
- Prolyl 3-hydroxylase 3
Sequence:
MGPRSPTAALLVLLCVGCAPTPGRGQYERYSFRSFPRDELMPLESAYRHALDQYSGEHWAESVGYLEVSLRLHRLLRDSEAFCHRNCSAATPAPAPAGPASHAELRLFGSVLRRAQCLKRCKQGLPAFRQSQPSRSVLADFQQREPYKFLQFAYFKANDLPKAIAAAHTYLLKHPDDEMMKRNMEYYKSLPGAEDHIKDLETKSYESLFVRAVRAYNGENWRTSISDMELALPDFLKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIRCEETLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQSDRVMQQNLVYYQYHRDKWGLSDEHFQPRPEAVQFFNVTTLQKELYDFAQEHLMDDDEGEVVEYVDDLLETEESA
Protein: DNA repair protein rhp7 (RAD7 homolog) (O74999)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in global genome repair (GGR) via nucleotide excision repair (NER), in conjunction with rhp16, after UV irradiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- ATP-dependent helicase rhp16
- DNA repair protein rhp26
- DNA repair protein rhp41
- Elongin-C
- DNA repair protein rad14
- DNA repair protein rad16
- DNA excision repair protein ckn1
- DNA repair protein rhp42
- Mating-type switching protein swi10
- UV excision repair protein rhp23
Sequence:
MSSGSRVRGPNSALTEFLRSQGINASALGRARPPRQSEESAGQSTGTESEVIQTPTSVEENNEDENSMSTTTIEIPVVKRRNLRNQKKKKKTDEEAEDNEDTFSMNSRAGFSYKAREHTGKLDFCAHCNCRFTITPYSKYSNSEKGWLCYPCSRGAEDRSVPELRTRKRKALTRKKVAAATMDEEISVPKLQDLCIRVIAEYINDIEAFGDIGQVNMDKISQIISKNRSLNDTTVKLFLSGGQTELKLYDCSKITADSLFQIAQYCPNLQTLHLTYCGQMQDQVLHFYADHLTELTDVSFQGAFLVSSSEWINFFKKRGSKLISLELTDTARIHVSVINAIVDCCPNLISLNLSRIFYLDDECVRLLAGCRNLVSLKIESPGGIINDGSILDVLNQIGSGLHTLSLSGCTKLTDEVLKQGIGPCCGRLKHLNLSGLELLTDDEASIVFGEWKIQSGLETLSLRRCLSLGDKTVRAVLVNSGHTLRTLDLNGMSFVTDEALQYIVNFPLPMLKALDVSWIRGMNDKLVCDFESKKPTLEKLLVWGDNHVLMPSNRLLLIGREVQ
Protein: Secreted protein (O53527)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Conserved protein
- Possible oxidoreductase
- Conserved protein
- Possible exported protein
- Uncharacterized protein Rv1271c
- Acyl-CoA:diacylglycerol acyltransferase
- Signal peptidase I
- Uncharacterized protein Rv1352
- DUF5642 domain-containing protein
- Diacylglycerol kinase
Sequence:
MSGHRKKAMLALAAASLAATLAPNAVAAAEPSWNGQYLVTLSANAKTGTSMAANRPEYPHKANYTFSSRCASDVCIATVVDAPPPKNEFIPRPIEYTWNGTQWVREISWQWDCLLPDGTIEYAPAKSITAYTPGQYGILTGVFHTDIASGTCKGNVDMPVSAKPIVG
Protein: Hemagglutinin glycoprotein (Q83639)
Organism: Measles morbillivirus
Subcellular location: Host cell membrane {ECO:0000256|ARBA:ARBA00004336}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004336}. Virion membrane {ECO:0000256|ARBA:ARBA00004208}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004208}.
Interaction partners:
Sequence:
MSPQRDRINAFYKDNPHPKGSRIVINREHLMIDRPYVLLAVLFVMFLSLIGLLAIAGIRLHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLETRTTNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLSRGYNVSSIVTMTSQGMYGGTYLVEKPNLSSKGSELSQLSMYRVFEVGVIRNPGLGAPVFHMTNYFEQPVSNDLSNCMVALGELKLAALCHGGDSITIPYQGSGKGVSFQLVKLGVWKSPTDMQSWVPFSTDDPVIDRLYLSSHRGVIADNQAKWAIPTTRTDDKLRMETCFQQACKGKIQALCENPEWAPLKDHRIPSYGVLSVDLSLTVELKIKIASGFGPLITHGSGMDLYKSNHNNEYWLTIPPMKNLALGVINTLEWIPRFKVSPNLFTVPIKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPSRSFSYFYPFRLPIKGIPIELQVECFTWDQKLWCRHFCVLADSESGGHITHSGMVGMGVSCTVTREDGTNSR
Protein: Glycerol-3-phosphate acyl transferase (EC 2.3.1.15) (E9ACF5)
Organism: Leishmania major
Interaction partners:
- glycerol kinase
- Glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate dehydrogenase-like protein
- Glycerol-3-phosphate dehydrogenase [NAD
- Dihydroxyacetonephosphate acyltransferase
- Putative lipin
- Putative phosphatidic acid phosphatase
- Alkylglycerone-phosphate synthase
- Diacylglycerol kinase
- Dihydroxyacetone kinase 1-like protein
Sequence:
MAPTSALKPKDRIVASTRRSKFVLCEECHQNVPIEEWPDHRDRLRKVSLVEEVSRFHHTLVRLMGEFLMWVLRSVYFREVTVVGRENIPCTGAVVFYGNHQNQFIDALMMHSHCGRPVRFLMAEKSFQRPVIGTLGRIFNSVPVVRPQDVPLVDGEGKLVRTEGKFIVGAGTHFSRLSKGDVLSWGVPGNAKCRAQVSRITSDEEVEVTVPIPAEHEVHTPTSFKYSVRIDHSEMYAQVYDTLQKNHCIGIFPEGGSHDHTSLLPLKAGVALFSLGAAERHISVKIVPVGLTYLYGHKFRSRAYIEFGEAFSPPDDLVKLFDTDKRKATGLFLEQLNAALRAVTINVPDYKTLSFLHSFRQLYQPPNCMLSGHDYLRLIRRLGNVIEEQRKSAEFAEFREKVENYSDFCKALMIRDSQAATLKRLLNADNEALQVGLLLRRVFALYLMAVILVPFFVVGLPIGGIIKYLALKQTKRALSESSVKIVGADVTGSFKVLFAFAVVPGVFLLVTFIVFLYSDSRTALVILFSLPMAMYVSLLILQEAIMELRAALPLLMSLVSQHMQFKKLYERREDLARQARLIVHKYDPQLEEEIKVHGNAGDSNDDLNREPSLFSLRYNVRRRQATNS
Protein: Peroxisomal catalase (EC 1.11.1.6) (O13289)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Required for hyphal growth.
Subcellular location: Peroxisome matrix {ECO:0000250|UniProtKB:P15202}.
Interaction partners:
- 3-hydroxyanthranilate 3,4-dioxygenase
- Kynureninase
- Peroxisomal hydratase-dehydrogenase-epimerase
- Oleate-induced peroxisomal protein POX18
- Oleate-induced peroxisomal protein POX18
- Superoxide dismutase
- Thioredoxin reductase
- Glutathione reductase
- Cell surface Cu-only superoxide dismutase 5
- Thioredoxin
Sequence:
MAPTFTNSNGQPIPEPFATQRVGQHGPLLLQDFNLIDSLAHFDRERIPERVVHAKGSGAYGVFEVTDDITDICAAKFLDTVGKKTRIFTRFSTVGGELGSADTARDPRGFATKFYTEEGNLDLVYNNTPVFFIRDPSKFPHFIHTQKRNPETHLKDANMFWDYLTSNEESIHQVMVLFSDRGTPASYREMNGYSGHTYKWSNKKGEWFYVQVHFISDQGIKTLTNEEAGALAGSNPDYAQEDLFKNIAAGNYPSWTAYIQTMTEAEAKEAEFSVFDLTKVWPHKKYPLRRFGKFTLNENPKNYFAEVEQAAFSPAHTVPYMEPSADPVLQSRLFSYADTHRHRLGTNYTQIPVNCPVTGAVFNPHMRDGAMTVNGNLGSHPNYLASDKPVEFKQFSLQEDQEVWNGAATPFHWKATPADFKQAQELWKVLKRYPNQQEHLAHNIAVHAAGADAAIQDRVFAYFGKVSQDLADAIKKEVLELSPRK
Protein: Small ribosomal subunit protein uS15c (30S ribosomal protein S15, chloroplastic) (P56805)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS4c
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Small ribosomal subunit protein uS11c
- At1g64880
- Small ribosomal subunit protein bS16cz
- Small ribosomal subunit protein eS7y
- 50S ribosomal protein L33
- Small ribosomal subunit protein uS2c
- Small ribosomal subunit protein uS9c
- Small ribosomal subunit protein uS9m
Sequence:
MIKNIVISFEEQKEESRGSVEFQVFSFTNKIRRLTSHLELHRKDYLSQRGLRKILGKRQRLLAYLSKKNRVRYKELINQLNIRELKTR