wanglab/gogpt-training-data huggingface dataset:
Protein: Prolyl 4-hydroxylase 2 (AtP4H-2) (AtP4H2) (EC 1.14.11.2) (F4JAU3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins. Hydroxyprolines are important constituent of many plant cell wall glycoproteins such as extensins, hydroxyproline-rich glycoproteins, lectins and arabinogalactan proteins. Possesses high affinity for leucine-rich repeat and proline-rich extensins of root cell walls that are essential for root hair development. Hydroxyprolines define the subsequent O-glycosylation sites by arabinosyltransferases which elongate the O-arabinosides on extensins. Has low affinity for the substrates tested in vitro.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:21680836}; Single-pass type II membrane protein {ECO:0000305|PubMed:21680836}. Golgi apparatus membrane {ECO:0000305|PubMed:21680836}; Single-pass type II membrane protein {ECO:0000305|PubMed:21680836}. Note=Predominantly localized in the endoplasmic reticulum. {ECO:0000269|PubMed:21680836}.
Interaction partners:
- Pyrroline-5-carboxylate reductase
- Proline iminopeptidase
- Proline dehydrogenase 2, mitochondrial
- Proline dehydrogenase 1, mitochondrial
- Arabinosyltransferase RRA3
- Arabinosyltransferase XEG113
- Hydroxyproline O-arabinosyltransferase 3
- Arabinosyltransferase RRA1
- Hydroxyproline O-arabinosyltransferase 1
- Phytanoyl-CoA dioxygenase
Sequence:
MSMSRLGLLLFVAILLVLLQSSTCLISSPSSIINPSKVKQVSSKPRAFVYEGFLTDLECDHLISLAKENLQRSAVADNDNGESQVSDVRTSSGTFISKGKDPIVSGIEDKLSTWTFLPKENGEDLQVLRYEHGQKYDAHFDYFHDKVNIARGGHRIATVLLYLSNVTKGGETVFPDAQEFSRRSLSENKDDLSDCAKKGIAVKPKKGNALLFFNLQQDAIPDPFSLHGGCPVIEGEKWSATKWIHVDSFDKILTHDGNCTDVNESCERWAVLGECGKNPEYMVGTPEIPGNCRRSCKAC
Protein: Peregrinol diphosphate synthase CPS1, chloroplastic (EC 4.2.1.174) ((+)-copalyl diphosphate synthase 1) (MvCPS1) (A0A075FAK4)
Organism: Marrubium vulgare (White horehound)
Function: Involved in the biosynthesis of labdane-type diterpenoid including marrubiin and other labdane-related furanoid diterpenoids with potential applications as anti-diabetics, analgesics or vasorelaxants (Probable). Terpene synthase that produces peregrinol diphosphate from geranylgeranyl diphosphate (GGPP).
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MASTPTLNLSITTPFVRTKIPAKISLPACSWLDRSSSRHVELNHKFCRKLELKVAMCRASLDVQQVRDEVYSNAQPHELVDKKIEERVKYVKNLLSTMDDGRINWSAYDTAWISLIKDFEGRDCPQFPSTLERIAENQLPDGSWGDKDFDCSYDRIINTLACVVALTTWNVHPEINQKGIRYLKENMRKLEETPTVLMTCAFEVVFPALLKKARNLGIHDLPYDMPIVKEICKIGDEKLARIPKKMMEKETTSLMYAAEGVENLDWERLLKLRTPENGSFLSSPAATVVAFMHTKDEDCLRYIKYLLNKFNGGAPNVYPVDLWSRLWATDRLQRLGISRYFESEIKDLLSYVHSYWTDIGVYCTRDSKYADIDDTSMGFRLLRVQGYNMDANVFKYFQKDDKFVCLGGQMNGSATATYNLYRAAQYQFPGEQILEDARKFSQQFLQESIDTNNLLDKWVISPHIPEEMRFGMEMTWYSCLPRIEASYYLQHYGATEDVWLGKTFFRMEEISNENYRELAILDFSKCQAQHQTEWIHMQEWYESNNVKEFGISRKDLLFAYFLAAASIFETERAKERILWARSKIICKMVKSFLEKETGSLEHKIAFLTGSGDKGNGPVNNAMATLHQLLGEFDGYISIQLENAWAAWLTKLEQGEANDGELLATTINICGGRVNQDTLSHNEYKALSDLTNKICHNLAQIQNDKGDEIKDSKRSERDKEVEQDMQALAKLVFEESDLERSIKQTFLAVVRTYYYGAYIAAEKIDVHMFKVLFKPVG
Protein: Protein GZF3 (P42944)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histone deacetylase HDA1
- Nitrogen regulatory protein DAL80
- Forkhead transcription factor HCM1
- Transcriptional regulatory protein GAT1
- Nitrogen regulatory protein GLN3
- Ammonium transporter MEP2
- Transcriptional activator protein DAL81
- Transcriptional regulator URE2
Sequence:
MASQATTLRGYNIRKRDNVFEPKSSENLNSLNQSEEEGHIGRWPPLGYEAVSAEQKSAVQLRESQAGASISNNMNFKANDKSFSTSTAGRMSPDTNSLHHILPKNQVKNNGQTMDANCNNNVSNDANVPVCKNCLTSTTPLWRRDEHGAMLCNACGLFLKLHGKPRPISLKTDVIKSRNRKSNTNHAHNLDNFRNQTLIAELKGDCNIESSGRKANRVTSEDKKKKSSQLLMGTSSTAKISKKPKTESKERSDSHLSATKLEVLMSGDCSRPNLKPKLPKQDTAIYQEKLLTFPSYTDVKEYSNSAHQSAFIKERSQFNAASFPLNASHSVTSKTGADSPQLPHLSMLLGSLSSTSISNNGSEIVSNCNNGIASTAATLAPTSSRTTDSNPSEVPNQIRSTMSSPDIISAKRNDPAPLSFHMASINDMLETRDRAISNVKTETTPPHFIPFLQSSKAPCISKANSQSISNSVSSSDVSGRKFENHPAKDLGDQLSTKLHKEEEIIKLKTRINELELVTDLYRRHINELDGKCRALEERLQRTVKQEGNKGG
Protein: RNA helicase (EC 3.6.4.13) (Q38AN5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- U3 small nucleolar RNA-associated protein 14
- Sas10 C-terminal domain-containing protein
- Probable eukaryotic initiation factor 4A
- Pre-mRNA-splicing factor SLU7
- U3 small nucleolar RNA-associated protein 25
- MI domain-containing protein
- Nop14-like protein
- RNA helicase
- Pre-mRNA-splicing factor 18
- Nrap protein domain-containing protein
Sequence:
MSDELCVLRKLQLIYSKNELYHRLEHVLGRPESAAEAEGLYDDVEGLVSLFAEANEKKRDSDDLKEVSAEERNKSLVDALDSAINGDENDEPPIQLSQLQDLACLMRSLLGDIDWSKCLAAGALAIVEQERREIEETLRQKILQEEEARRDANEGGDSAAGRQRTLQDLSVDPAERRAAMKVRAEEKMQLAQLVRTGLLDESELLQVKTDDEDVEQVELNEEEPLFLRGLVRHKPINYRALLPSEQLMRASTPAQREAIIARRVVQQACAEEIETNTMKRAALAQQQRNKERQILQAKERRQQRLAEQARGFYEPNDAADRKEEGDDEEGNNEEDGTHYKGNTFLDRELLERPEEHLHRGGLGRGSRSALPPWMKHSFGEKPRFGMMETSESLAEQRRSLPIYAFRDRFLQHVDAHAVTVLVGETGSGKTTQIPQYLVEHGYGKNGVVCCTQPRRVAAETLAIRVAEEYGCRLGEEVGYTVRFRDVTSSLTCIKYMTDGMLLREALLDDSFQRYSVIILDEAHERSVNTDLLFAIVRNATHKRPTLKVIVTSATLEREKFCSYFNVHDVFFIEGRTFPVDTYFLAEPTEDYLDCALKTVMKLHLEEPPGDVLVFLTGQEEIEFGGDRLFRWMERLRGLSDLPVPDMLILPLTATLPQDVQSRVFEPTPPHCRKVVLATNVAETSITISNLSYVVDSGYSKQNVFDPKTGMEQLKIMPISQAQARQRAGRAGRIGPGKCFRMYTEIQFRQDMDPATVPDIQRSNLFHVVLQLKAMGINDLFALDLMDPPPQETLVTALQKLRYLEALDEDGLLTPLGGRMAHLPIDPSHSKTLLTAVDLGCSEPVLTIVSMLAAQKRGVFYRPRDQHEAADAAKRQFHQPEGDHITLLAVYDAWVANGLSENWCKRNFLKHRMLMEARDTRDQLSEMLRKRHTNIEHHNDSSLTEVRRAITAGYFFNAARRITDVAYATLAERREVYVHPSSCLRDTPPKYLLYNEVQLTSREYMREILAIEPRWLVELAPAFYSKPRKGKLTKEQRAERLNPILRAWESGNSWRISKQRRRR
Protein: Tachykinin-related peptide 4 (TKRP-4) (P86597)
Organism: Pyrrhocoris apterus (Sap sucking bug) (Cimex apterus)
Subcellular location: Secreted {ECO:0000269|PubMed:19084564, ECO:0000305}.
Interaction partners:
Sequence:
TPASGFFGMR
Protein: Cystatin-9-like (Testatin) (Q9H4G1)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTFTCFFTISTRPWMTQFSLLNKTCLEGFH
Protein: Angiopoietin-2 (Q90Z18)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MGSLPCLCYLAAAVAVAIGSERRQHQVQHGPCRYTFILPEVEQCRPAGDFQVTNSLQRDSPSAPESPHAEPSWQERKLETLESATENNTQWLQKLESYIQENVRSEMERNVIHTQTATMLEIGTNLLSQSAENTCKLTDVETQVLNQTSRLEIQLLEYSLSTNRLEKQLLEQTQEVSRLNDKNSYMEQRFADMEAKHSRELQAIQQEKQQLLELLDRQNELVSLLEGELASSTRNSTLIQRQQASLTDTVQQLLAMVTHCNDISTPVDKEMLKFRDCAEIFKSGVTENGIYSIHLPNSTQKIKVFCDMKTKGGGWTVFQHRYDGSVDFNRDWNDYKLGFGDPSGEHWLGNDVIHLLTTTKDYTLQVHLKDAEEHQAYSQYDTFYIDGEDKKYSLHARGFSGTAGRTSSLTHSGTQFSTKDQDNDQCSCKCAQMATGGWWFEACGPSNLNGIYYSGNSNVIRYNSIKWYYWKGPSWMATMTTMMIRPVDF
Protein: Aquaporin-1a.2 (Aquaporin-1b) (B6CMI5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MARELKSWSFWRAVLAEFVGMTIFVFIGIASAIGNKHNRYPDQEVKVALAFGLAIATLAQSLGHISGAHLNPAITLGLLVSCQISFFRAFMYIIAQMLGAVLASGIMFKVSPDPDTTLGLNMLGNGVKVGQGFAIELFTTFQLVLCALATTDKNRTDVSGSAPLAIGLSVGLGHLVAISYTGCGINPARSFGPAVVLESFKNHWIYWIAPMCGGVAAALIYDFLLFPKREALRKRMNVLKGTADPDPSATEALIEPRSARSGSGQWPRP
Protein: Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (G5ECH7)
Organism: Caenorhabditis elegans
Function: Proline-directed serine/threonine-protein kinase which, in several motor neurons, promotes the polarized trafficking of synaptic vesicles and dense-core vesicles (DCV). In the ventral nerve cord, phosphorylates lin-10 and thereby prevents lin-10-mediated anterograde trafficking of the glutamate receptor glr-1. Involved in the inhibition of glr-1 trafficking in hypoxic conditions. In DA motor neurons but not in DB motor neurons, regulates axonal transport of synaptic vesicle precursors by inhibiting dynein-mediated retrograde transport. Regulates the trafficking of dense-core vesicles in DA and DB motor neurons by promoting anterograde trafficking to the axon and preventing dynein-dependent trafficking to the dendrite. May regulate these processes in association with cdka-1/p35. Activity may be regulated by cyy-1. Involved in synapse formation during DD motor neuron remodeling by regulating transport of disassembled synaptic material to the new synaptic sites probably by activating the motor protein unc-104/kinesin-3. Regulates microtubule polarity in the dendrite of DB motor neurons. May also play a role in GABAergic synaptic vesicle localization in the ventral nerve cord.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20510931}. Cell projection, dendrite {ECO:0000269|PubMed:20510931}. Note=Localizes predominantly to presynaptic sites and in dendrites as faint puncta. {ECO:0000269|PubMed:20510931}.
Interaction partners:
- Cyclin-dependent kinase 5 activator 1
- Microtubule-associated protein
- Cyclin-Y
- Presenilin sel-12
- Presenilin hop-1
- Presenilin spe-4
- Actin
- G2/mitotic-specific cyclin-B
- Cyclin N-terminal domain-containing protein
- Protein nud-2
Sequence:
MLNYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFADTSDV
Protein: Mnn4-4p (A0A1D8PQ19)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Globin family profile domain-containing protein
Sequence:
MSLVKSITSAKSSNKLIKVILFTLVFINLIYFTSVIHNNNKERISSITSKLTSSTSGNNNKQQEQHLTDADNDKLSSSSNQQQQDAHETVLEEQEKEQQTQQQQSLSDDDIQFKKLVDAKLNSVKKNQGKYYMTNTDLSETKIKVPIKQFLKKYESAESWINKNELYYDPRFTLSIYLNELYMQYQEMSDEQLIDGNDNQHLIGGKINSNELPDISLPFNWVDWIDLTMLNKEFSKPMYQRLKCQDIQANSHSNPDTSYFCTDNEDISEETFQEFFKMGYKYKTQFPGFIINDHERHEHYCDNDYRVMQAKAYTMTHLLNPLKVIILGADKKDGNGGTFEFSVDNSKTRLTSSKLIDRYMESHGYYTRKQDSNIDTVRNGKRFFFDSSEDQNEVPDIIEMDYLSTWNQLNEKVVPKYLSPNETGYTNFLHMRDKNSIVLKESKFMEPPSIASQIEQYTGKPENELSPQEKLYLEGLQECSKYTDENEVRYFRMAVINPGDPRNRENEWGWHYDWRFFNGALNYEKPDWNQQELTHRTNIILDRLLRNWSKFAMEKGIITWIMHGPLLSWYWNGLLFPYDNDIDIQMPIDELVNLAKNYNQTLIVENPSEGYGKYLIEVNTYFHNRGISAEQNHIDARFHDVDSGIYIDITALSSSNAEVPKEYKQEKTIQLIDDLTKTNSNKEGAGNNGKQVNSENQLIFNDRRKHFYKIDQISPLKFSMMQGIPVMVPNGITNRLQFEYSKGLKSLEFDNWFYIKQLNLWVQKDNIIPILEDQTRTSNEDILKQIQPPSSLSNDQILKLLNNEEILQEYYLTRSLTRFHDFEKQVLFDDNGNDKPLDLVKYKTYKKGLKMVKPLRKALYEYENIERIKHHH
Protein: Vasorin a (A8DZ86)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MRPLSPLSHLILLQLLCGCLSSRCPHDCTCLPNNNIFCVQRNLIYMPRGLPSTGKQLYVFQNKINILQQQDFVELGELEMLDLSQNSLSEIPDGVFSPLSSLHNLDLSSNYITHISKDSFIGLVNLERLYLYSNIIQNIHPAAFEGLENLLELKLQGNQISVLPALQLPRLLHLDLSYNSIPPLVAQDLQTPHLESLKIAGLGLTSLDEELLGSLVNLHVLDVSQNQLVDIQPTLKSMGGLRNLNLTGNPLGSLKHEDFQNLVNLLELDLSNLNLQGFPEGFFNLFPKLEKLTAAENPFNCLCPLAWFPAWLKDVRVELLRTEETRCHFPPINSGKVLEKLEHKDFGCPTTTIELTSAGTSSTTSKPKNSSTQLGTTHIVPPAPPSDISSADADNFPVYQTTAFPSRIMEDSEGEGIMCPPNICLNGGTCIFKSNGVIVCLCPPSMSGNYCEIQNEAMLPPPSPRVSLETIATVQPNTISSHHITSTSISLDLHRYIQTRPHIRGIRLTYSNLSGPDRRPLQLSVPPSYPEYTLRGLQPNSTYSVCASPLGEPVHASVSACMEARTAGIPPSSHEPSVDRTEPSSSLTPIVVAVAVVMVVAIIATVVVISRRRRPKAPVDMDLHETSPLEMEGVKTNPENGLTHPKQPDITPCSSLAPNSLEYDVLLIQGQGQCPANNNIDCTKALYV
Protein: Probable aspartyl protease At4g16563 (EC 3.4.23.-) (Q940R4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- U-box domain-containing protein 45
- BTB/POZ domain-containing protein At2g30600
- At1g14330/F14L17_7
- F-box protein PP2-A14
- Probable CCR4-associated factor 1 homolog 5
- U-box domain-containing protein 29
- F-box/kelch-repeat protein At1g15670
- Kelch repeat-containing protein At3g27220
- RNA-binding protein BRN2
- RING-H2 finger protein ATL79
Sequence:
MKTCLIFFLYTTILQYYFHFSVSSLSTPLLLHLSHSLSTSKHSSSPLHLLKSSSSRSSARFRRHHHKQQQQQLSLPISSGSDYLISLSVGSSSSAVSLYLDTGSDLVWFPCRPFTCILCESKPLPPSPPSSLSSSATTVSCSSPSCSAAHSSLPSSDLCAISNCPLDFIETGDCNTSSYPCPPFYYAYGDGSLVAKLYSDSLSLPSVSVSNFTFGCAHTTLAEPIGVAGFGRGRLSLPAQLAVHSPHLGNSFSYCLVSHSFDSDRVRRPSPLILGRFVDKKEKRVGTTDDHDDGDDEKKKKNEFVFTEMLENPKHPYFYSVSLQGISIGKRNIPAPAMLRRIDKNGGGGVVVDSGTTFTMLPAKFYNSVVEEFDSRVGRVHERADRVEPSSGMSPCYYLNQTVKVPALVLHFAGNRSSVTLPRRNYFYEFMDGGDGKEEKRKIGCLMLMNGGDESELRGGTGAILGNYQQQGFEVVYDLLNRRVGFAKRKCASLWDSLK
Protein: Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, gizzard smooth muscle) (P10587)
Organism: Gallus gallus (Chicken)
Function: Muscle contraction.
Subcellular location: Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Interaction partners:
- Myosin light polypeptide 6
- Myosin regulatory light chain 2, smooth muscle major isoform
- Actin, aortic smooth muscle
- Actin, cytoplasmic 1
- Actin, alpha cardiac muscle 1
- Myosin regulatory light chain 2A, cardiac muscle isoform
- Myosin regulatory light chain 2B, cardiac muscle isoform
- Myosin regulatory light chain 2, smooth muscle minor isoform
- EF-hand domain-containing protein
- Actin, cytoplasmic 2
Sequence:
MSQKPLSDDEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFSYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQGNHAKFQKSKQLKDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIIAFQAQCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEKLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDLEEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKLEGESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQEDLESEKAARNKAEKQKRDLSEELEALKTELEDTLDTTATQQELRAKREQEVTVLKRALEEETRTHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKTKQTLEKDNADLANEIRSLSQAKQDVEHKKKKLEVQLQDLQSKYSDGERVRTELNEKVHKLQIEVENVTSLLNEAESKNIKLTKDVATLGSQLQDTQELLQEETRQKLNVTTKLRQLEDDKNSLQEQLDEEVEAKQNLERHISTLTIQLSDSKKKLQEFTATVETMEEGKKKLQREIESLTQQFEEKAASYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQMLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELEDELQAAEDAKLRLEVNMQAMKSQFERDLQARDEQNEEKRRQLLKQLHEHETELEDERKQRALAAAAKKKLEVDVKDLESQVDSANKAREEAIKQLRKLQAQMKDYQRDLDDARAAREEIFATARENEKKAKNLEAELIQLQEDLAAAERARKQADLEKEEMAEELASANSGRTSLQDEKRRLEARIAQLEEELDEEHSNIETMSDRMRKAVQQAEQLNNELATERATAQKNENARQQLERQNKELRSKLQEMEGAVKSKFKSTIAALEAKIASLEEQLEQEAREKQAAAKTLRQKDKKLKDALLQVEDERKQAEQYKDQAEKGNLRLKQLKRQLEEAEEESQRINANRRKLQRELDEATESNDALGREVAALKSKLRRGNEPVSFAPPRRSGGRRVIENATDGGEEEIDGRDGDFNGKASE
Protein: Serine/threonine-protein kinase ATR (EC 2.7.11.1) (A0A8I6G5M3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLLDFIQHIMKSSPLMFVNVNGSQGQNEAKDSCIEFSHWIITRLLRIAATPSCHMLHKKICEVICSLLFLFKSKNPAIFGVLTRELLYLFEDLIYLHKRNAVGDVMEWPVVVSRFLSRLDEHMGCLQPAPLQFMNMQNVEFIEVTLLMVLIHIVPTVFFRRQELLLWQIGCALLEHGSPKIRSLAISLLTELFELGGLPAQPASTFFSLFLELLQHLIGMDADQLKLYEEPLSKLVKTLFPFEAEAYRNIEPVYLNVLLEKLRVMFEDRVLMRLKSDLLKAALCHLLQYFLTFVPAGYESALQVRKVYVTDICRALVDVLGVQTHVGYLLGPFYAALKMESTEIIERIQCQAQQENLRGSNDGVSPKRRRLSSSLSSYKRPSRQSEEINHVDMDKKSILWNVLKQKAESLQISLECGTLKNSVAEALEGITIVLQLTALCTVHCSHQDMDGHNAKDCQHKYKKKPPVVITWMSLDFYTKVLKSCKSLLESVQKHELELVIDSVVRIYDALMYIQVKSSFQDHVLEELCGMLSLPWIYSYSDDNSLKMTTFATNLLRLSQRVWESYSPQAQSQCVFLLTLFPKRIFLDWRTTVYNWALKSSHEVIRTSCVKGFFILLQQENSCNQIPKMLIDRVKDDSHVVKKEFASVLGQLVCTLHGMFYLTSSSVEPFFGPVDLFCKNLKATSQHECSSSQVKASVCKPFLFLLTKNTPSPVKLAFIDNLHHLCKHLDFQEDETEVKAVLGTLLNLMEDPDKDVRIAFSGNIKYILESLNSEDGFIKELFVLRMKEAYTHAQISRSNELKDTLILTTGDIGRAAKGDLIPFALLHLLHCLLSKSASVSGAAYTEIRALVAAKSVKLQNFFSQYKKPICQFLVESLHSSQMTALPSTPCQTAEMRKQHVAHHREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDITSPELMADYLQPKLLGILAFFNMQLLSSSVGIEDKKMALTSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHAYLGPLLSHVIVALLPLIQMQPKETAAIFHYLIIENRVAVQDFLHEIYFLPDHPELEKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIKYATDSETVEPVISQLVTVILKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKDFTFVTGVEDLSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMQSNGPGHQLWKRFPEHVREILEPHLNTRYKSSQKSTDWSGVTKPIYLSKLGNNFAEWSSSWAGYLITKVRDNLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCSQEDQQEVYAEIMAVLKHDDQHAISTQDSASDLCQLSTQTVFSMLDHLTQWARHKFQALNAEKLAQNKPKGVSSVNFEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQKHLGFLQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESIGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSVRLGQLLLSAKKRDTTAFYDTLKLVRAEQIVPLSAASFERGSYQRGYEFIVRLHMLCELEHSLKPLFHKFPGDSCNEDSLNWAARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVELCFPENKSPTESKHMLIHGRATLLVGRFMEETANFESNAIMKKYKDVTLFLPEWEDGHFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLSLWLDFGAKAYEWEKGGRSDRLQMRNDLAKINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILTKAIHMKKSLEKFVGDATRLTDKLLELCNKSVDGSNSTLSMSTHFKMLKKLVEDPTFSEILIPLQSVMIPTLPSILGAHANHDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFQEILLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPPNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM
Protein: UPF0597 protein YhaM (P42626)
Organism: Escherichia coli (strain K12)
Function: Plays a role in L-cysteine detoxification; it has been speculated to be a cysteine desulfhydrase.
Interaction partners:
- Probable serine transporter
Sequence:
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
Protein: Protein Shroom3 (Shroom3v2) (K7X477)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MMQVTQGGVGAPWHQSYHSSASTTDLSGFEAGFLRKSPDQYSSRGSMESLDHSHPAYSSCYHLSSSKSSSSIDHLHNKRDSAYSSFSTSSSIPEYLAATPSFNKERSYSMENVPQREGMQQADIRYVRTVYDNQQGVSEEHEITSAALMRTNDSRARSKSAIICHRGSSSSESSGSSGSTSSSQRQSFGPVWDPMHSRHSFENLKGAPAPPLRSDSYAAFRNHERPNSWSSLEHARSQRALSKGFWQHSSGSVATGKSSFGAEGQLHTVIEKSPESSPTTKPKQGIPQPAQPGRFMLPTGVYPVPPPEPHFAQIPTSNPNSGSVYPALAKESKHNNHCDRLGGLVKEDRLAAENGYQSNAPTLNPVQTLPLAEPRLSDRVQDDSQVKPSFYRPHFQPQMQKSQTPHVPLERRDPYTPVQPRGERQRYSVDSVYDNYRPARNEEQNKTNEETVHPDPIPSGKVVQGQAAQTYGGNFIQTQGNDNIVKPSRHYSDSIALRQRGQDLDNPLTRLENALAEVQRCVSPESTTSHCSFQSERSMSVLEKVSHFERQQVKPRSQSSLSHYGSTPRLNQPARPSSAKGSFSGKDGVRTMLERSNSSVTESYQRTESYDGHADMQQDFHTRRGSSNQIQYHQQQDPTVTQKKYLQRSKSTFQLGEGNGKGDIHDMLGAIQDTSFNRAYRDSLKDAQSKVLRSTSFRRRDFGVNPPPVPAKHMSLERKGTNTSPKAVTTSPHTPKERHVVPVEAQNRTTPPELPSVPAVGPPVLRICGRKRFTMEQKKRSYSEPENMHEVGVTQEINQVERRVQQQFLSSETSVADRRRMFEQVANRNADPRLFSSRPDLKQMQQDALVEYMERKTGRRIDGRPNRPQSAYIQSTSSSADSRSLSSTPSLSSLQEPGYDGLSGGIRKASTLPAGMQSNFYPNRATQIHTRPEVFGHQSQVPYPESHNPGPALTRHTLPQHLEVFERATTARTSGRSASAEDLLDRSEERPIPQHFRSKSSPVENVSQDFLARDLQLVRGSSKDFSENRLLANMGPKQPSISTRMERSYQLNQGPVQQNAPVLRRERQRYSDRPRAQSASGLAASVGLPCPLTSPGTNTHPDWQNGDRLCQPNLDSIAFPETGPQNQKSPSTAPGMIRQNSNDTSTSEDTLKDFPCLVNTPSPPTSSSSSKLSISPVSPTKPLLSLRISESSLHNMHNITRSQDDDEVFIAPPTPSPPPPPLPYREIEIMEDFPPPPPLTPPVDEDVGLTEISQHPLHPISSDENLTNATAHPEPEPPTTNSSTPPVSPLELDASEILGSDCYLLSRRERTHTERLVETLARELVKHDKSLTSLLDTWAGKTTLDLMEDIFPSHRTSSGHLDNRAQDGADSQTPPRKMETNLDDEEAYLNQKKVELLQALRASVQSLREERESLAEQQQVCAALGGSTEALVQERCKSNEKEKFRMFVGDLEKIVNLLLSLSARLARVENSLSALQEEEEHDDEKESLQLKQKQLRSQQEDARELKENLDRRERVVLDILAGYLSVPQLHDYQRFIRMKPALLIRQRHLDELIRQGEEQTQRLEESLPLQHHPKNTDSGPRPTHTLNSTHLPRPTTVTSL
Protein: Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF),-interacting protein (liprin), alpha 1 (S4R1I7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
QETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRCLPMKRALYRLLGSVAAAVGAPRVPCLQA
Protein: Small GTPase, putative (Q38AB6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLKRGGLNGVKVIVIGDGNVGKSSLLRRFVTGTFSNQYNRTVGVEYMEKSVCLRQRSTTVNLFLWDTAGQETVSSVKDIYYLDAAVAILVFSTDSSESFARIEMWKRCVERVCGSIPMVLCQTKFDLARQAAVVAEEVEKLAVKLQLPLFRVSTKDGFNVTQLFEYVAAMCVSEAPGGECGPSGKLKSEADGNGSTGAGNAGKSSKSGGAGKKSSKKSKKKKCSVM
Protein: Phosphate-specific transport system accessory protein PhoU homolog (Pst system accessory protein PhoU homolog) (PhoU-like phosphate uptake regulator) (O67053)
Organism: Aquifex aeolicus (strain VF5)
Function: Plays a role in the regulation of phosphate uptake. In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex (Probable).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15937186}.
Interaction partners:
- Phosphate transport system permease protein PstA
- Phosphate import ATP-binding protein PstB
- Transcriptional regulator
- Phosphate-binding protein
- Phosphate transport system permease protein
- histidine kinase
- PhoH-like protein
Sequence:
MKLFKELEETKEQVIKMAKLVQEAIDKATEALNKQNVELAEEVIKGDDTIDLLEVDIERRCIRMIALYQPEAGDLRMIMGIYKIVSDLERMGDEAENIAERAILLAEEPPLKPYVNINFMSEIVKEMVNDSVISFIQQDTLLAKKVIEKDDTVDELYHQLERELMTYVLEDPRNIKRAMHLSFVARHYERIADHAENVAEAAIYLSEGEIVKHQHIKEKGE
Protein: Probable xyloglucan endotransglucosylase/hydrolase protein 12 (At-XTH12) (XTH-12) (EC 2.4.1.207) (Q9FKL9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
Subcellular location: Secreted, cell wall {ECO:0000305}. Secreted, extracellular space, apoplast {ECO:0000305}.
Interaction partners:
- Fasciclin-like arabinogalactan protein 6
- Proline-rich protein 1
- Proline-rich extensin-like family protein
- Peroxidase 60
- Extensin-like protein
- Proline-rich extensin-like family protein
- Leucine-rich repeat extensin-like protein 1
- Protein SEED AND ROOT HAIR PROTECTIVE PROTEIN
- Proline-rich protein 3
- Putative pectinesterase/pectinesterase inhibitor 24
Sequence:
MAAFATKQSPLLLASLLILIGVATGSFYDSFDITWGAGRANIFESGQLLTCTLDKTSGSGFQSKKEYLFGKIDMKIKLVPGNSAGTVTAYYLSSKGETWDEIDFEFLGNVTGQPYVIHTNVFTGGKGNREMQFYLWFDPTADFHTYTVLWNPLNIIFLVDGIPIRVFKNNEANGVAYPKSQPMKIYSSLWEADDWATQGGKVKTDWTNAPFSASYRSFNDVDCCSRTSIWNWVTCNANSNSWMWTTLNSNQLGQLKWVQKDYMIYNYCTDFKRFPQGLPTECNLN
Protein: UPAR/Ly6 domain-containing protein (Q8R0G1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MFWSSVSKSLLAVCVVTEFAVIFVESFSCENSMCTNGFCQPMGTCNTSKSCFSQTQEFKMPELSTSLSVQQKGCSLDECTGLAFSATLGDQRTFRYDQRCCTTDKCNQVDTKPSQVPAKANGVQCLACYMEAGRVCIPTPLKCTGSETKCVAVIGTAVGSSSPLSVVMVGSGCATESACNLNMTVLDFVNIRTFCSSGFPVFPTPSSAPDGLGLRSASISTVPVLISLLLLKVLV
Protein: Macrocin O-methyltransferase (MacOMeTase) (EC 2.1.1.101) (Tylosin biosynthesis protein F) (Q9S4D5)
Organism: Streptomyces fradiae (Streptomyces roseoflavus)
Function: O-methyltransferase that catalyzes the conversion of macrocin to tylosin, the ultimate step of tylosin antibiotic biosynthesis. Also able to mediate the conversion of lactenocin to desmycosin.
Interaction partners:
Sequence:
MAPSPDHARDLYIELLKKVVSNVIYEDPTHVAGMITDASFDRTSRESGEDYPTVAHTMIGLKRLDNLHRCLADVVEDGVPGDFIETGVWRGGACIFARGLLNAYGQADRTVWVADSFQGFPELTGSDHPLDVEIDLHQYNEAVDLPTSEETVRENFARYGLLDDNVRFLAGWFKDTMPAAPVKQLAVMRLDGDSYGATMDVLDSLYERLSPGGYVIVDDYCIPACREAVHDFRDRLGIRDTIHRIDRQGAYWRHSG