wanglab/gogpt-training-data huggingface dataset:
Protein: Interleukin-1 receptor antagonist protein (IL-1RN) (IL-1ra) (IRAP) (IL1 inhibitor) (P25085)
Organism: Mus musculus (Mouse)
Function: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Subcellular location: [Isoform 1]: Secreted {ECO:0000250|UniProtKB:P18510}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Interaction partners:
- Interleukin-1 receptor type 1
- Interleukin-1 receptor type 2
- Interleukin-1 alpha
- Interleukin-6
- C-C motif chemokine 2
- Tumor necrosis factor
- Interleukin-10
- C-reactive protein
- Interleukin-1 beta
- Interleukin-1 receptor-like 2
Sequence:
MEICWGPYSHLISLLLILLFHSEAACRPSGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNIKLEEKIDMVPIDLHSVFLGIHGGKLCLSCAKSGDDIKLQLEEVNITDLSKNKEEDKRFTFIRSEKGPTTSFESAACPGWFLCTTLEADRPVSLTNTPEEPLIVTKFYFQEDQ
Protein: Protein kri1 (Q09799)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- KRR1 small subunit processome component homolog
- Probable nucleolar complex protein 14
- Ribosomal RNA-processing protein 7
- Ribosome biogenesis protein erb1
- Ribosome biogenesis protein bms1
- ATP-dependent RNA helicase rok1
- U3 small nucleolar ribonucleoprotein protein mpp10
- Uncharacterized protein C3B8.09
- ATP-dependent RNA helicase mak5
- Uncharacterized protein C57A7.06
Sequence:
MPRKKSAAKKAREALVQKKVINSNVPTDKKSIDQLQENVTSKSHLLEESSSEDEEINSFQINEEYAKRFEHNKKREELQKLEAKYGEQMANGVDGEGSDESSSEEEEDSDGELVTPEVDAAILRMIVKIRNKDPDLYDSQQKYFDEVEKDVQGSLKSKDGFRSVTLKDYHRQKLLSGEILDAEEDEPMPNDANPTHVEEQERLRKETIAAFHDVNGNKDAVSNESDEDGDFLVKKEKTKKQLEEEEHGYERFLLESAQSKEARKVLEDLSSSYVKQRPSVLVNTEDDENGIKPSDEDFLLKYMMNRGWRTSNTKQPSYEEIIDEVDAENRFDEDAEEFENKFNFRFEEEAGSQIVSHPRNVADSLRRKDDSRKRARDRKKERLEEASQKRLEEVNRLKNLKRKELEEKLNQVIEIAGSKNIDVSKLDLDEDFDPEKWESKMSEIFNENYYEEDSAKKPEFGDDIDIDDIAQVDNGSEDLGSIENKTVEDTGNREKSKKSLRKDIREKKRKIDEYVEEKYGVPEAVIVKNSKFRYQQVAPETFGLDILDILNASDADLNNYVGLKKMTPYRTPEEIARDKKKYGKKKRLREWKKQVFGK
Protein: Chloroplastic calcium uniporter protein (cMCU) (Calcium uniporter protein 6, chloroplastic) (AtMCU6) (Q9LVR5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:31182842}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Calcium uptake protein, mitochondrial
- IQ domain-containing protein IQM4
- Cation/calcium exchanger 2
- Calcium-transporting ATPase 1
- Probable cyclic nucleotide-gated ion channel 14
- Calmodulin-binding protein 25
Sequence:
MSSKKSLVQSLFNISKTYSRISGLTRMRPTKSGGIPPDAGDSGIRRRFLHKRAFFSPEIVPKGGNLMEKLRELTLSNNNRIRLDEMLPPPSPKKSSPEFFPAVTVEDVKKLMRAAEMELVKSKLREIGKNWVPYSEFVRVCGEYSSDPEQGNRVANMLDEAGNVIVLGKLVCLKPEELTSAMAGLIPTLEPSLDAETRQEFEQLEIIKSDIDKRADDLVRKELWAGLGLIMAQTVGFFRLTFWELSWDVMEPICFYVTSTYFMAGYAFFLRTSKEPSFEGFYKSRFETKQKRLIKMLDFDIDRFTKLQKMHRPNLTKSGRC
Protein: C3H1-type domain-containing protein (Q57WW2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAERRQPRVLGAQRTVSEVLGPKPVDISDIRLLIDRCVGGAVDSTPTLGELERVLSYFARHNSGYIRAGVDDLHILASEILNNNTRAVMVFGEFGSSFGDVEMYLISVVVQYNMSLEAITINAVNVSDDAVSMLCEALTKSRVSFIDLSNTPLESEAGHSLAALAHVNPYVRTIILDDTLVAEEVLDEIDVACQFNQSNFEANGGVVDPGGTAEVARIRHRIRSIIRAKHKKIIYCVPHVLGTCPDGDMCMFSHTPMTSGAPDTNANLHERIVDVFAVGGGLNKLPAPPKAGASWKNPEELGEHTLRLNLEKCRPGKASRKEVSDDGGMLRKSLMITVIPVALVAASVCALRLWKR
Protein: Red chlorophyll catabolite reductase, chloroplastic (AtRCCR) (RCC reductase) (EC 1.3.7.12) (Accelerated cell death protein 2) (Q8LDU4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC). Works in a two-step reaction with pheophorbide a oxygenase (PaO) by reducing the C20/C1 double bond of the intermediate, RCC. Belongs to the chlorophyll catabolic enzymes (CCEs).
Subcellular location: Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane. Note=And a low amount in mitochondria of 7-day-old seedlings.
Interaction partners:
- Pheophorbide a oxygenase, chloroplastic
- 7-hydroxymethyl chlorophyll a reductase, chloroplastic
- Pheophytinase, chloroplastic
- Chlorophyll
- Probable chlorophyll
- DNA repair protein RAD4
- Magnesium dechelatase SGR1, chloroplastic
- Magnesium dechelatase SGRL, chloroplastic
- Transcription and mRNA export factor ENY2
- Chlorophyllase-1
Sequence:
MAMIFCNTLYSSSSPSYLSPLTSKPSRFSKNLRPRAQFQSMEDHDDHLRRKFMEFPYVSPTRKQLMVDLMSTVENRLQSQLLPCNLPPDVRNFNNPNGSAEASLHIRSGDKSSPIDFVIGSWIHCKIPTGVSLNITSISGFLNSSTKAPNFVVELIQSSSKSLVLILDLPHRKDLVLNPDYLKEYYQDTALDSHRQSLLKLPEVNPYVSPSLFVRSAFSPTASMLKIDAEEEDKLEEILRDHVSPAAKEVLEVWLERCVKEEEEKIVVGEEERMELERRDKSFRRKSIEDDLDLQFPRMFGEEVSSRVVHAIKEAFGVL
Protein: N-sulfoglucosamine sulfohydrolase (sulfamidase) (G3XA02)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MHCPGLACCTILLVLGLCGAHSRNVLLIVALSSVTPSRLSAAVPRAVPASSPACPSIRMACMGCTRMCITSTLLTRYRAFRCCSTRPECAQASLGRSTWVRRRCIPLTLHSQRRTAL
Protein: Major facilitator superfamily (MFS) profile domain-containing protein (O62376)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MVQTMSSRKVMVFVVTFVSYGLYHASRKALSGVKSSIKADWLSNSSGHAPLFTNEADAKHFLGSLDAIFMAAYAAALFFWGWLGDRLNPKLVVAAGMVGSAVTLTLFGAIPKWFNFYHAPYYIMTYVAFGLVQACGWPSEIAIMANWFGKGNRGFVMGVWAACQPVGNIFGSIFTAMVLPLGYQYTFVFNSVLIALGAIVVVMAIDSSPNEEHEDGVEANSSEPHHNFHGEPISLFKAVLLPGVLAYCICNACLKLVNYAFFFWLPLYLTDAYHWEESQADQLSIWYDFGGIIGSVLGGYITDKMGKRSPLIVAMLVCSIGSLYFYAHVGPHMFWNAVVMTTVGVTVSGPYNLIVGSISIDLGSQPALAGNTQAMSTVSGLLDGTGSAGSAVGQLLIPIIQDDLGWKAVFYVFMLLNGFAILAILKRCIIDLKSLRKLRSGEESPLLNDEAGDHED
Protein: Two-component response regulator ARR3 (Q9ZWS9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histidine kinase 4
- Histidine-containing phosphotransfer protein 3
- Histidine kinase 3
- Histidine kinase 2
- Two-component response regulator ARR18
- Two-component response regulator ARR22
- Two-component response regulator 24
- Histidine-containing phosphotransfer protein 5
- Putative two-component response regulator-like APRR4
- Histidine kinase 5
Sequence:
MAKDGGVSCLRRSEMIGIGIGELESPPLDSDQVHVLAVDDSLVDRIVIERLLRITSCKVTAVDSGWRALEFLGLDDDKAAVEFDRLKVDLIITDYCMPGMTGYELLKKIKESTSFKEVPVVIMSSENVMTRIDRCLEEGAEDFLLKPVKLADVKRLRSYLTRDVKVAAEGNKRKLTTPPPPPPLSATSSMESSDSTVESPLSMVDDEDSLTMSPESATSLVDSPMRSPGLA
Protein: Citrate synthase 3, mitochondrial (EC 2.3.3.1) (P43635)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Dual specificity mitochondrial citrate and methylcitrate synthase with similar catalytic efficiency with both acetyl-CoA and propionyl-CoA.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:9140965}.
Interaction partners:
- Citrate synthase, mitochondrial
- Acetyl-coenzyme A synthetase 1
- Aconitate hydratase, mitochondrial
- Malate synthase 1
- Malate dehydrogenase, mitochondrial
- Acetyl-coenzyme A synthetase 2
- Malate dehydrogenase, peroxisomal
- Malate dehydrogenase, cytoplasmic
- Pyruvate carboxylase 1
- Pyruvate carboxylase 2
Sequence:
MVQRLLPGAHICRRSFNSSAIIKSSALTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTLEDSLNLIASLPLLTGRIYSNITNEGHPLGQYSEEVDWCTNICSLLGMTNGTNSSNTCNLTSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLIEMNSNISSIAREQEIKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAMLEFAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHYGIRELLFFTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLEGLEALTKASNVNKL
Protein: Zinc finger SWIM domain-containing protein 8 homolog (Protein dorado) (Q9VWN9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex that promotes target-directed microRNA degradation (TDMD), a process that mediates degradation of microRNAs (miRNAs). The SCF-like E3 ubiquitin-protein ligase complex acts by catalyzing ubiquitination and subsequent degradation of AGO1, thereby exposing miRNAs for degradation (By similarity).
Interaction partners:
Sequence:
MDRFSFDDSIRFEEDSLCSWSSEPESLCNNWRGWKKPAAGSGAGNGGLSGMGGMAVAGGSGAPPFGGAGASGSCTPGGNGTAMANTSTCGRHYEVSTLAELAARCVASYIPFELVEHVYPPVPEQLQLRIAFWSFPDNEEDIRLYSCLANSSADEFNRGDSLFRLRAVKDPLQIGFHLSASVVNQTPRAYFNVAVTFDRRRISSCNCTCTSSAYWCSHVVAVCLHRIHCPQEVCLRAPVSESLTRLQRDQLQKFAQYLISELPQQILPTAQRLLDELLSAQPTAINTVCGAPDPTAGASINDQTSWYLDEKTLHNNIKRILIKFCLPAPIVFSDVNYLTNSAPPAAAEWSSLLRPLRGREPEGMWNLLSIVREMYRRCDRNAVRLLEIITEECLYCDQILIWWFQTKLALMMGSHGHSGGKHSNTHSNSTALQHACSSLCDEIVALWRLAALNPGLAPDERDMLHAQFTAWHLKILDRVVKSRMMPSYTNKHQQNSRSETELFIGFKPAIEACYLDWEGYPIPGVTHTHDTNPIYYSPFTCFKHTDLKGESNNPGQLNATQALMSNNKHYNYFSSSSDHGMHAGAFKQRLDRPFRESRFYTNPADLDGGAALAGGGSGRFSTGLGSVAVGGAGAGGLGQMSGGVNNSVGGSAAAEVNPVQQQLPSGSAGVGASVTNAKVVVATDGNRSSASSEGFCENDDFGGDTSSSHNYCPPGQAVVPGQKSALTESDSQSSFDAVSHQSKDEPPVGGVGVAVGVEQALSTSDTSSASSSSSSASTASGSSNSSTSSMLMAGQEATVGVGGAVQQTTRRLSKDESFSSSSDEFNQGGVGGSAGRVAMASSGSGSGAGDTVAVGSGSTAGGDLTPVPSTSAAARAALAASSTGPVISASPHLAASAAGGLGVLGVGADQPCTSSAHAARALAAAVAASSDKPHVFSNVRPTEDAWDILLARAEGLHAHGHGAEACILAVRLAEQMLANPPNLLLELPPAPKRKGKKQNVNPISHQLTVVASATLSKCAFLCTVLSENSEHYHIGFRICLFALEMPRPPASTKPLEVKLANQEADILALLKRLPLGSAELQVIRERAEQLRSGTFKTRGEALLPINLATFIFDALVTLSPLGGSTIVPGVASTSGVSSAAGKSMVNTGTRLLLYKHNSDESLGFDAAVAALGLKANVSEAEHPLLCEGTRRQRGDLALTLLSHYKDEPRKIAKIMEKLLDRDIHTLLNAPLLPAYYSSNPPVRTRSNQPTRREDHDYGGGSGCASSNCNPVANLCELLPADYGSVGGNSRPHSSTSAELELSMCALSMASSGSQSGGVQGMVPTTNAAGTTGTPSSSSTTVSGSQNPNGNPSGSGGGGNGGGGNGGGGGGGGGGGGSTSSRSKESRYKGKRAYPSIPNQPSEASAHFMFELAKNVLTKAGGNSSTSLFTQASTSQNHHGPHRALHMCAFQLGLYALGLHNCVSPNWLSRTYSSHVSWILGQAMEIGAPAISFLIDTWEAHLTPPEAAGMADRASRGWDSNMVYPAAELALSVLPHAAALNPNEIQRAILQCKEQSDLMLERACLTVETAAKGGGVYPEVLFQVARYWYELYMRNTPNNSEFEPHDDTMDHSAVSLSALIESQQQHELQQQQQAVQQQQAVQQQQQVVQQQQQVVQQQQQLGMPNSVVPGGVGPGPGLPVAVQPPVVGSVQNPQAQFQPVGVASLAPLGLAQYPPYSFCQGLYAHHHNMSYPPGQMQMFISAGPPPPPQAYGGYQQPPPQQPPNPQQQQQVVQQQVQQQQVVQQQQQQVQMAGQAPPGHPGQQGHPGQPPSGFQPQPPPGAFQALPPQAYQAMQAGPPGPPMGPPQGYYGPPPPPPPNGPPGVGVGVGVGVGVGVMPMRQHQHQHPVYPFMQQAPPQPPQQQQPPPSQPPVRQRQPHQFTPTQLRYLLAAYNVGMLAMETLARRVHDDRPQAKYARNPPYGEDVKWLLRISKKLGTQYLHQFCICAVNSIVSPFVLHDVAIESAHYLGRNNHQMVMQHLRSALTPLVQKCQQMYIQCIHQKLYHLTQGDYEEFASIVVAARAAFQITPEGNAQFKDWLQSIKRSKSCKKELWTQINAALQSNSK
Protein: Aminotransferase PigE (EC 2.6.1.-) (A0A0J9X1Q5)
Organism: Serratia sp. (strain FS14)
Function: Involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig). Catalyzes the transamination to the aldehyde group of 3-acetyloctanal, resulting in an aminoketone, which spontaneously cyclizes to yield the dihydro form of MAP (H2MAP).
Interaction partners:
Sequence:
MKFGFIAHPTSLGLKRYVKMLDLLQRNSTEQHSGYTRELWERQNLVPFMNFARITSATGATCEGVIKYMPLVADEMLADARGIAARVVQGIEELAGDGAELVGLGGFTSIVGRRGEATAEKSPVPVTSGNSLTTYAGYKALMQIQSWLEIRPEEEPVAIVGYPGSICLALSRLLLAHGFSLHLLHRAGNHDRSELLSHLPEEYHSRVTLTSDPEDLYPRCKLFAAATSAGGVIDPARLQPGSIFIDVALPRDIASETRPARDDILIIDGGCVTATDAVKLGGESLNVTIKQQLNGCMAETIVLALENRRENFSLGRYLAPEKVLEIGEIAERHGFFAYPLASYGERIDRQSVTNLKRYYHHDIYAGESADAALPASRLAFIDAVIAQTPAREDTLDRYHQYINPMMVDFLKLQRCDNVFRSAAGTQLYDDAGEAFLDMVAGYGCLNLGHNPQPVVNALKNYLDAQGPNFIQYISIPEQTAKLAEVLCRLAPGNMGRVFFSNSGTEAVEAAMKIAKASTGKPGIAYLRNSYHGKTLGALSITGRDKHRRYFTPLLDAMVEVPFGDLAALREALNREDVGALMIEPIQGEGGVHIPPAGYLQAVQQLCRETGVLLMVDEVQTGLGRTGKLFACEWDGIEPDVLMLSKSLSGGLIPIGATLCRADLWQKAYGTADRFLVHSSTYGGGNLASVVALSALREILAQDLVGHAERMGAYFKQALSEIAARYPFVSEVRGRGLMLGIQFDQAFTGAVNASAREFATRLPGDWHTTWKFLPDPVQAHLRAAMDRMEQALGEMFCMKFVTKLCQDHKILTFITANSSTVIRIQPPLIISKAEIDRFVGAFATVCEELSTFLD
Protein: D-erythrose-4-phosphate dehydrogenase (E4PDH) (EC 1.2.1.72) (A5F9G1)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Function: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01640}.
Interaction partners:
Sequence:
MLRVAINGFGRIGRNVLRAVYESGKRDRIQVVAVNELAKPDAMAHLLQYDTSHGRFGKKISHDQQHIYVHHQNGEYDSIRILHLSEIPLLPWRDLGVDLVLDCTGVYGCQEDGQQHIDAGAKLVLFSHPGASDLDNTIIYGVNHETLTAEHKIVSNGSCTTNCIVPIIKVLDDAFGIDSGTITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVRVPTVNVTAMDLSVTIKSNVKVNDVNQTIVNASQCTLRGIVDYTEAPLVSIDFNHDPHSAIVDGTQTRVSNGQLVKMLVWCDNEWGFANRMLDTALAMQATQ
Protein: Serine/threonine protein kinase (A0A1D8PH81)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Serine/threonine protein kinase
- Serine/threonine-protein kinase
- Ras family GTPase
- Uncharacterized protein
- Rga2p
- Cell cycle protein kinase DBF2
- non-specific serine/threonine protein kinase
Sequence:
MAYNNNNNSSNYNYNFNRHNSIGGNWHLPPPPPPPTQLTSSGAYHHQQQQQHSQQHLSPNHPNGQDILSSSDSQFSSQLKQNQIPGFRNPWFSQQQNSTPNMLSSSSSASSSLSQSPTKSHQIPLLQQHQPPLLNKRLSFTNNLPITYEHESSSNSSSNNNSSSNGNGNNNNNDNNTNVPPYIHPPTRADNPFNHYFATQEVTLGSNDRRMSAAVDGTHYNPYGFNQQLNAYPSGPAGIAGTQYLNNPNLGPSVNANRRSSVGVLPNYYRQQQQQQVQDQSTAAAAAAAAAAAYYLPPARLGRSASIVQYQQYQQALQNQRITKHKNPAPKARKIYNKLDLTPKFHQQPKYRRCSINSIHISPVNALSIYLTESYSLCQPRKFQYSKSTNPKRVLTKPSEPKYNNGYDNEDSDYILYVNDVLGSEEGKKYMVLDLLGSGTFGQVVKCQNLNNQTVCAVKVIKSKPAYMNQSLTEVRLLEFLNANSDGKNFIRLLDTFMHKEHLCLVFEILASNLYELIKQNQFQGLNMKLVKLLTKQLLDSMAQLKNFQMIHCDLKPENILLCQPDKPNIKVIDFGSACFTRNTIYTYIQSRFYRSPEVILGLPYTESIDMWSLGCIVGELFLGLPMFPGTSEYNQIFKIVDMLGPPPRHMIEVGKNSFNFFKKKVNTTTTTINNNNNNTSETKPIYELKSFDEYCQFLEYKRQKQEGATSTTNNNTNSSSSSNHHHNNYKKEQPNKNYFKHKLLKDIIINYKLPSKKMTNSMIEKEYHDRLLLIDFLTKVLNLNPLERLTPQEALKHPFIIDVNTTDL
Protein: Isocitrate dehydrogenase [NAD] subunit, mitochondrial (G5E9Q7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|RuleBase:RU361266}.
Interaction partners:
Sequence:
MIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENVRFPSHPTLLPRPVSPCSLL
Protein: Coagulation factor VII (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Cleaved into: Factor VII light chain; Factor VII heavy chain] (P70375)
Organism: Mus musculus (Mouse)
Function: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).
Subcellular location: Secreted.
Interaction partners:
- Tissue factor
- Tissue factor pathway inhibitor
- Coagulation factor X
- Vitamin K-dependent gamma-carboxylase
- Prothrombin
- Thrombomodulin
- GDP-fucose protein O-fucosyltransferase 1
- Coagulation factor IX
- Coagulation factor VIII
- Antithrombin-III
Sequence:
MVPQAHGLLLLCFLLQLQGPLGTAVFITQEEAHGVLHRQRRANSLLEELWPGSLERECNEEQCSFEEAREIFKSPERTKQFWIVYSDGDQCASNPCQNGGTCQDHLKSYVCFCLLDFEGRNCEKSKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYTLQPDEVSCKPKVEYPCGRIPVVEKRNSSSRQGRIVGGNVCPKGECPWQAVLKINGLLLCGAVLLDARWIVTAAHCFDNIRYWGNITVVMGEHDFSEKDGDEQVRRVTQVIMPDKYIRGKINHDIALLRLHRPVTFTDYVVPLCLPEKSFSENTLARIRFSRVSGWGQLLDRGATALELMSIEVPRLMTQDCLEHAKHSSNTPKITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVRHMDSKLQVGVFRLPLL
Protein: At5g41090 (Emb|CAB88055.1) (NAC domain containing protein 95) (Q9FLM0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At1g60280
- C2H2 and C2HC zinc fingers superfamily protein
- C2H2 and C2HC zinc fingers superfamily protein
- Nuclear transcription factor Y subunit C-5
- C2H2 type zinc finger transcription factor family
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Uncharacterized protein
- Glycine-rich protein homolog
- STAY-GREEN-like protein
- Uncharacterized protein
Sequence:
MGPTYRALPVGMRFRPSDLELAVYFLIKKALGLPMKALTVPDECNDIFSTHPRDLPGYGSEEHWYFYCKKPKNQVTRTKSYNLWIPTGEKTDVLDPKKNGGELVGIKHSFTFIENEEEEESDNKNGDEEEPPQCNWFLDEISLPLTVVDTDWTLCHIFYEKVKPEFGNLHIVESESESEEEEEDESVDKPAESLDSVKEKDGTVLPPPPATP
Protein: Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Peptidase M) (H1UBK1)
Organism: Caenorhabditis elegans
Function: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for germ cell proliferation and/or differentiation.
Subcellular location: Cytoplasm {ECO:0000255, ECO:0000255|HAMAP-Rule:MF_03175}.
Interaction partners:
- Methionine aminopeptidase
- Putative sphingolipid delta
- Putative sphingolipid delta
- Large ribosomal subunit protein uL30
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein uL14
- Ubiquitin-like domain-containing protein
- Small ribosomal subunit protein uS3
Sequence:
MPPANGKKGKKGGAAKAVRRIQYRPKSFKHSRFVKHAHFWSAAPEEDFDAILAEMQLADAKTAAKEATKKDAKGGKGKANGSAAATAAPEEAKQAWQAEIAAMKPIDEQFPDGKFPHGIDESPYYLKGKDGRVATDRESNEEKKALDISYEEVWQDYRRSAEAHRQVRKYVKSWIKPGMTMIEICERLETTSRRLIKEQGLEAGLAFPTGCSLNHCAAHYTPNAGDTTVLQYGDVCKIDYGIHVRGRLIDSAFTVHFDPKFDPLVEAVREATNAGIKESGIDVRLCDVGEIVEEVMTSHEVELDGKSYVVKPIRNLNGHSIAQYRIHAGKTVPIVKGGEQTKMEENEIYAIETFGSTGKGYVHDDMETSHYMKNFELADEKIPLRLQKSKGLLNLIDKNFATLAFCRRWIDRLGETKYLMALKDLCDKGIVDPYPPLCDVKGCYTAQWEHTILMRPTVKEVVSRGDDY
Protein: Polychaetoid, isoform I (B7Z0U1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDIVSGSATGNQLVLPNNHFRHESFQQQGDRTTWEYHTVAVTRVPGYGFGIAVSGGRDNPHFANGDPSIAVSDVLKGGPAEDRLQVNDRIISVNGVSLENVEYATAVQVLRDSGNTVQLVVKRRVPLNPINAAGAVQHQHSHSLSSVGLMANGSGGVAPTPITSLSQPNSLNSSLVQNASSGQPIKVTLTKGGKKDDYGVVLGCRLFVKEISSKAREQLNANGYSLQEGDIITRIHNTNCGDTMSLKEAKKIIDGCKERLNLVVLRDITNQTAVSQLNLNNSASHQASGNIYATHQPQVSGCSSSNNNLEDPYLPGGASYSSQNLYVQPPTRTSNGPNINGNGLNDEKSNLTPRGRSRGPIMDGVSLQQLDRPVTPTRGRSAAIDEPPRPPPPRGSSGGAAQEDFYSSRRQLYEERQSAEPRFISFQKEGSVGIRLTGGNEAGIFVTAVQPGSPASLQGLMPGDKILKVNDMDMNGVTREEAVLFLLSLQDRIDLIVQYCKEEYDEVVTNQRGDSFHIKTHFHCDNPSKGEMAFKAGDVFRVIDTLHNGVVGSWQVLKIGRGHQEMQRGVIPNKSRAEELATAQFNATKKEMNANESRGNFFRRRRSTHRRSKSLSRENWDDVVFSDSISKFPAYERVVLRHPGFVRPVVLFGPVSDLARERLAKDFPDKFSTPLQDDDKSAATSGKCRIVRLSNIRDVMDRGKHALLDITPNAVDRLNYAQFYPVVIFLKTDSKHVIKQLRHGLPKAAHKSSKKLLEQCQKLERVWSHIFSTQIALSDEESWYRKLRDSIDLQQSGAVWMSESKPVESLSDDFLFPMTTSRLSYASSPESDLELSPGPSASLSLGNLPQLVKASSDPSIATNQDNLDRDRDIIGEGLPPPYTVPYDHAVPANPNRRQTMDSSKYSIYGTNVPPQQQQPGVGGDTAAVRPQSLYGINAPDLPPRIDRQSKPGDIPLNTSGSSSRNGTLGRSAQERLFGKAVVQDDVQAEYITRNALVGSGAAETLDRQQQQQQQTHASLERQARLNAQLKANGVGAGGGGASTYDSVSSYDSYNNTQMAMQNLGRLGPNAPDDLKSVPNANGRPLPPTGQSHEYGRTPHDHRSFGGPNDLNRQSSPGRPHYHDMNASRNIDPRNGTPQRPSNLGLESSPRKPLVETKTDYGKYSRNNSVTQADYTKLPKTAPHGVVPPPNVSNGQGQMNGSGTPSSNGSGPFKPVPPPKPKNYRPPVQSGGSSGSGGTTPWENGDSGSPRSPNGFYYPPTPSHHHYGQQATPGSPSNGHMQPPPPQQQQPTYGGSNGNYGQAPPPQSYPQANGYNGNGHHYNGGSGTGPYIAPHRGMPPPIGNLPPHTPERHALDLAGSREQRGSAFELYRKPQIGATAGHHHNMR
Protein: At5g45170 (Haloacid dehalogenase-like hydrolase (HAD) superfamily protein) (Q6NMA9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEIASCSILNNLQISCTKTSIFTQYLSERSSHDTGRRNFLPFSNFPGKSQILGKCLRLQRFSSICLSASREDVNPSEEFAVILEVDRVMIDTWSSNRQAFNVAFQKLGLDCANWPEPVYSDLLRKGAADEEKMLLLYFNQIGWPSSLPTSEKASFVKSVLREKKNAMDEFLISKSLPLRSGVQEFIDNAYAEKVPVAIVTAYCKSGDKVALSIVEMLGQERLPNVKVIGDNEVEQSMYGQLVLGKGVSSSLEEQLVKEVKKAASAEKQRIAEEVASMLKLSVDIDTTSSERLEKIVVALRAAAEHIGLPVNNCVLVAGSQPGVSAAKMIGMPCVVMRSSLTARGEFPSAKGVMDGFGGADLTIPKLRNKIKS
Protein: Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) (F1LNY6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 11
- Transcription initiation factor TFIID subunit 10
- TATA box binding protein
- Transcription initiation factor TFIID subunit 13
- Transcription initiation factor TFIID subunit 9B
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 3
Sequence:
MPPTGLESSRMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDLEAAFIYNDPTLEVCHSESKQRNLNYFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLKIHINFSLDQPKGGLHFVVPSVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYVLAIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYHHWIKEELDKIVAYELKTGGVLLHPIFGGGKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTYGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNKKKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYELRYERDVVAQQESILALEKFPTPASRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDASLFKSYAEYGHFVDIRIAALEAVVDYTKVDRSYEELQWLLNMIQTDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSGTAHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPEAGVGNQETASNPGCHTQLAGFQNPFSSSQDEEEVDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPSSSRSSLMPQHALGCDITPTTKPQWSMELSRKGAGKEQPLEMGVHPVAAPLSVFAKEALSSARHSEHHHHHHHEHKKKKKKHKHKHKHKHKHDGKDKDKDKEPFTFSSPASGRSVRSPSLSD
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (Q4VBR4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIRVQQMHRPKLIGEELAQLKEQRVHKTDLERVLEANDGSGMLDEDEEDLQRALALSRQEIDMEDEEADLRRAIQLSMQGSSRNISQDMTQTSGTNLTSEELRKRREAYFEKQQQKQQQQQQQQQQQQQQQQQQQGDLSGQSSHPCERPATSSGALGSDLGDAMSEEDMLQAAVTMSLETVRNDLKTEGKK