wanglab/gogpt-training-data huggingface dataset:
Protein: Vacuolar protein sorting-associated protein 29 (Protein MAIGO 1) (Vesicle protein sorting 29) (Q9STT2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. Required for the auxin-carrier protein PIN2 sorting to the lytic vacuolar pathway and the PIN1 recycling to the plasma membrane, thus influencing auxin transport orientation. Also involved in the efficient sorting of seed storage proteins globulin 12S and albumin 2S. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane.
Subcellular location: Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane {ECO:0000269|PubMed:29897620}; Peripheral membrane protein {ECO:0000269|PubMed:29897620}. Note=Colocalizes with and mobilized by VPS38/USL1 at late endosomes, probably in a PI3K complex-dependent manner. {ECO:0000269|PubMed:29897620}.
Interaction partners:
- Vacuolar protein sorting-associated protein 26B
- Vacuolar protein sorting-associated protein 26A
- Vacuolar protein sorting-associated protein 35A
- Vacuolar protein sorting-associated protein 35B
- Vacuolar protein sorting-associated protein 35C
- Sorting nexin 1
- Vacuolar protein sorting-associated protein 26C
- Sorting nexin 2A
- Sorting nexin 2B
- Sorting nexin
Sequence:
MVLVLALGDLHVPHRAADLPPKFKSMLVPGKIQHIICTGNLCIKEIHDYLKTICPDLHIVRGEFDEDARYPENKTLTIGQFKLGLCHGHQVIPWGDLDSLAMLQRQLGVDILVTGHTHQFTAYKHEGGVVINPGSATGAYSSINQDVNPSFVLMDIDGFRAVVYVYELIDGEVKVDKIEFKKPPTTSSGP
Protein: Ataxin 2 (F8WB06)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL
Protein: GDP-mannose transporter 1 (GMT 1) (Q5AS82)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- SNARE complex subunit
Sequence:
MTDNRKPEDYTIEMDKLGQNKNYQAPPPPPQPRSSTASSISNNAALSVLAYCGSSILMTVMNKYVLSSDFNLNFFLLCVQSLVCIIAIQLCKACGLITYRDFNLDEARKWFPITLLLIGMIYTGSKALQFLSIPVYTIFKNLTIILIAYGEVLWFGGSVTNLTLFSFGLMVFSSIIAAWADIKHAIESSGDATSKVSTLNAGYIWMLINCLCTSSYVLGMRKRIKLTNFKDFDTMFYNNLLSIPVLIVCSGILEDWSPANVARNFPSADRNGIMFAMILSGLSTVFISYTSAWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPVTFPSVSAIMVGFVSGIVYAVAKIKQNAKPKVGILPTTNPVSASSQSMRDSLRS
Protein: SD10481p (Q960B0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQNSKAKMDEFKSKFLDILHKQTNRQMKIPAMGFSDYFIQTVTTDASASQETDATDAAATSSSESNAQKSDQEILESIEQCYYNPDSNPQLYELKKVLNDGIDNELIEVTIAQLRTQQKVLTKQVLQNILEQRNACSSEFAAINDTQKKLEESLWTCQKARSYLNFARTNLTTTSLEILASYRKREVLKEVLDTLVAIKRLRTTDVEVQKLLADHNYSAAIALLLQCKSSAEAYMQFNCVQSLSKKLQETMLLMEFQLDTVLNEMVLGFDGRKYAKLQEAYKLANKSLMAMDQLHINYISAIHSSVNAVLRGYSDPGQDDQAKPLYEQLCEQLSVDKLLPCLISLCKTFWTILASYYQVVMWHNNYKLYGQEEEDSPDIYIQQKLKKGQSRVWNDILTKVCLFLQSAKLTALKYDQFIQVLSVVQRLKKVGLEFCGEQSEKLIETMQQQSEEFFRRYHICCIEEICLFLDNESWTQVDSFAHILQLPEFRSVRHTLRRHKSPTAALLASSNNSPISNNNCDELVSVHSQDGGSSIYGSYGYFLRFSEKSSPFDGGLDAAMLEEDILSGIVDEASCYFSEESDDEQKSLQSKEFDDASNQLLVNNTALNVMRVIGRYLQMCKLLHCISPKIVACILELIDFYVYAVHEIFGKDAPVATDNMHSPRLEQRLRSVEVNVLPQIKLWPLNFSSLANNELANPDTLYGLSQRIVAVEAGRSMLQQFNVLQHYLNHLLPLAERPILASYLDYSDYIADLAKLVYTCVTSRVIDLSSILAQMAKVKWDVNHVIHQHSNYSDVLNRNIQSFAMCLEEIAKEVPVPSKQVWNSMAHVATHLLVEGFSNVKKCSAGGRALMQLDFANFMSFLELISNQKYPQHRSYVDVFIKTYYFAPEQFEQWIEQQRAGDEYSLKQLNNLIHCICVSDKRTRQRLLQLLDAGIQNGIAMSTTPTTTPQKNNHGSVAGSNLSSVI
Protein: RNA helicase (EC 3.6.4.13) (A0A2R8YFR4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASRRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Protein: Serine/threonine-protein kinase H2 (EC 2.7.11.1) (Protein serine kinase H2) (PSK-H2) (Q96QS6)
Organism: Homo sapiens (Human)
Interaction partners:
- Neuronal migration protein doublecortin
- Protein unc-119 homolog B
Sequence:
MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL
Protein: Transmembrane protein 135 (Q8N605)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MAALSKSIPHNCYEIGHTWHPSCRVSFLQITGGALEESLKIYAPLYLIAAILRKRKLDYYLHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMANLMESHCLPQAGVISAPCSLCLPGSRDSPA
Protein: Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13) (Q15645)
Organism: Homo sapiens (Human)
Function: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation.
Interaction partners:
- MAD2L1-binding protein
- Cell division cycle protein 20 homolog
- Mitotic spindle assembly checkpoint protein MAD2A
- Mitotic spindle assembly checkpoint protein MAD2B
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Shieldin complex subunit 3
- Kinesin-like protein KIF20A
- Cytochrome c1, heme protein, mitochondrial
- Maternal embryonic leucine zipper kinase
- Targeting protein for Xklp2
Sequence:
MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTEFDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENIIAANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDKQFEERKKLAAYI
Protein: BON1-associated protein 1 (Q941L2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Negative regulator of cell death and defense responses. Exhibits calcium-dependent phospholipid binding properties.
Subcellular location: Membrane {ECO:0000269|PubMed:17018034}; Peripheral membrane protein {ECO:0000269|PubMed:17018034}.
Interaction partners:
- Protein BONZAI 1
- Zinc finger protein ZAT12
- AAA-ATPase At3g28580
- Zinc finger protein ZAT10
- At3g48450 family protein)
- Nudix hydrolase 7
- At1g32920/F9L11_25
Sequence:
MIYFGRSIDNHYTTMMTKTLEIDLRSAEGLKLNRRPIKKKTFAVVKIDEKCRKSNLDESRRSNPTWNYKSEMPINGNEQFIFIEVFYRTGSGHDKKIGEAKIPTNDFMGRYSPEGHLNFLSYRLRDEFGDKCGIVNLSILVKSDPTRDYGACSSQAAVTGLWRPRLETASIDGYGGRTVTGVPVWGLYQRQF
Protein: Endolytic murein transglycosylase (EC 4.2.2.29) (Peptidoglycan lytic transglycosylase) (Peptidoglycan polymerization terminase) (P28306)
Organism: Escherichia coli (strain K12)
Function: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_02065, ECO:0000269|PubMed:26507882, ECO:0000269|PubMed:33278861}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_02065, ECO:0000269|PubMed:26507882}. Note=Access to the inner membrane is important for in vivo activity. {ECO:0000269|PubMed:33278861}.
Interaction partners:
- Aminodeoxychorismate lyase
- Thymidylate kinase
- Uncharacterized metal-dependent hydrolase YcfH
- DNA polymerase III subunit delta'
- Membrane-bound lytic murein transglycosylase D
- Acyl carrier protein
- Penicillin-binding protein 1B
- Membrane-bound lytic murein transglycosylase A
- Endolytic peptidoglycan transglycosylase RlpA
- Membrane-bound lytic murein transglycosylase B
Sequence:
MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTLKPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLLESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGWFWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKETAVASERDKVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTITGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVLKEKNAQ
Protein: 19 kDa globulin (Alpha-globulin) (allergen Ory s 19kD) (P29835)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Seed storage protein.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Cyclin-C1-1
- Cyclin-dependent kinase E-1
- Os02g0732700 protein
- Os06g0217500 protein
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 7
Sequence:
MASKVVFFAAALMAAMVAISGAQLSESEMRFRDRQCQREVQDSPLDACRQVLDRQLTGRERFQPMFRRPGALGLRMQCCQQLQDVSRECRCAAIRRMVRSYEESMPMPLEQGWSSSSSEYYGGEGSSSEQGYYGEGSSEEGYYGEQQQQPGMTRVRLTRARQYAAQLPSMCRVEPQQCSIFAAGQY
Protein: TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV) (O43715)
Organism: Homo sapiens (Human)
Function: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:15735003, ECO:0000269|PubMed:23931759}. Mitochondrion intermembrane space {ECO:0000269|PubMed:23931759}.
Interaction partners:
- PRELI domain-containing protein 1, mitochondrial
- PRELI domain containing protein 3B
- PRELI domain containing protein 3A
- Cellular tumor antigen p53
Sequence:
MNSVGEACTDMKREYDQCFNRWFAEKFLKGDSSGDPCTDLFKRYQQCVQKAIKEKEIPIEGLEFMGHGKEKPENSS
Protein: Transaldolase (EC 2.2.1.2) (P37837)
Organism: Homo sapiens (Human)
Function: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. Not only acts as a pentose phosphate pathway enzyme, but also affects other metabolite pathways by altering its subcellular localization between the nucleus and the cytoplasm (By similarity).
Subcellular location: [Isoform 1]: Nucleus {ECO:0000250|UniProtKB:Q93092}. Cytoplasm {ECO:0000250|UniProtKB:Q93092}. Note=Shuttles between the nucleus and the cytoplasm. Actively transported into the nucleus in an importin alpha/beta-dependent manner. Exported into the cytoplasm by CRM1. {ECO:0000250|UniProtKB:Q93092}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000250|UniProtKB:Q93092}. Note=Imported into the nucleus when incorporated in isoform 1/isoform 2 homodimer. {ECO:0000250|UniProtKB:Q93092}.
Interaction partners:
- Transketolase-like protein 1
- Transketolase-like protein 2
- Transketolase
- Ribose-5-phosphate isomerase
- Glucose-6-phosphate isomerase
- Triosephosphate isomerase
- Fructose-1,6-bisphosphatase 1
- Fructose-1,6-bisphosphatase isozyme 2
- ATP-dependent 6-phosphofructokinase, muscle type
- Glyceraldehyde-3-phosphate dehydrogenase
Sequence:
MSSSPVKRQRMESALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIHLDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK
Protein: Rac-like GTP-binding protein ARAC2 (GTPase protein ROP7) (Q38903)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation.
Subcellular location: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with the membrane when activated.
Interaction partners:
- Rho guanine nucleotide exchange factor 8
- KOW domain-containing protein
- Kinesin-like protein KIN-14E
- Rop guanine nucleotide exchange factor 4
- Rop guanine nucleotide exchange factor 2
- Dol-P-Glc:Glc
- Galactose oxidase/kelch repeat superfamily protein
- Rho GDP-dissociation inhibitor 1
- Immunoglobulin E-set superfamily protein
- At1g12070
Sequence:
MSTARFIKCVTVGDGAVGKTCMLISYTSNTFPTDYVPTVFDNFSANVVVDGSTVNLGLWDTAGQEDYNRLRPLSYRGADVFLLAFSLISKASYENIHKKWLPELKHYAPGIPIVLVGTKLDLRDDKQFLKDHPGAASITTAQGEELRKMIGAVRYLECSSKTQQNVKAVFDTAIRVALRPPKAKKKIKPLKTKRSRICFFL
Protein: Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27) (Q9Y573)
Organism: Homo sapiens (Human)
Function: May play a role in organizing the actin cytoskeleton.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Multiple inositol polyphosphate phosphatase 1
- Kelch-like protein 28
Sequence:
MANEDCPKAADSPFSSDKHAQLILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVVPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQIDPLNCIGIFQFSEQIACHDLLEFSENYIHVHFLEVHSGEEFLALTKDQLIKILRSEELSIEDEYQVFLAAMQWILKDLGKRRKHVVEVLDPIRFPLLPPQRLLKYIEGVSDFNLRVALQTLLKEYCEVCKSPKENKFCSFLQTSKVRPRKKARKYLYAVGGYTRLQGGRWSDSRALSCVERFDTFSQYWTTVSSLHQARSGLGVTVLGGMVYAIGGEKDSMIFDCTECYDPVTKQWTTVASMNHPRCGLGVCVCYGAIYALGGWVGAEIGNTIERFDPDENKWEVVGNMAVSRYYFGCCEMQGLIYVIGGISNEGIELRSFEVYDPLSKRWSPLPPMGTRRAYLGVAALNDCIYSVGGWNETQDALHTVEKYSFEEEKWVEVASMKVPRAGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITSRCEGGVAVL
Protein: Vesicle-associated protein 4-1 (Plant VAP homolog 4-1) (AtPVA41) (Protein MEMBRANE-ASSOCIATED MANNITOL-INDUCED) (AtMAMI) (VAMP-associated protein 4-1) (Q1ECE0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in vesicle trafficking.
Interaction partners:
- AT3g53990
- 3-isopropylmalate dehydrogenase 1, chloroplastic
- Transcription factor ALC
- Probable inactive 2-oxoglutarate-dependent dioxygenase AOP2
Sequence:
MPIGDRQNPSVEKKKNLFRLCPFWQRRSTTSSSSTQNPNQNYRSRHGNRNTDISAVSKPPLTMSSVARSLLPARRRLRLDPSSYLYFPYEPGKQVRSAIKLKNTSKSHTAFKFQTTAPKSCYMRPPGGVLAPGESVFATVFKFVEHPENNEKQPLNQKSKVKFKIMSLKVKPGVEYVPELFDEQKDQVAVEQVLRVIFIDADRPSAALEKLKRQLDEAEAAVEARKKPPPETGPRVVGEGLVIDEWKERREKYLARQQVESVDSLS
Protein: Mercaptopyruvate sulfurtransferase, putative (EC 2.8.1.2) (Q582K7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Adenylyltransferase and sulfurtransferase MOCS3 homolog
- Aspartate aminotransferase
- cysteine desulfurase
- Kynurenine aminotransferase, putative
- aspartate transaminase
- FAD/NAD
Sequence:
MHGDGLGRLHPGKVFLTIDEIKNGISSYQIFDVRYDLRNKEYGINQYNKGHVARATFVDLDRHLSGPVVECSKARHPMPDPHEFVEWCKSKGIGHFKPVLCYDDECGAMGACRMWWMLNALGVEAYVMTCGFKAYEAAGLPVESTPYDKNQSTSYWPYATEFKRLLKIKDIPPCAHMVDTRPALRFNTTVRPYGPDDIPGHIEGAVNLPYDVNILLVNRHEKRLRPNDECRSNTLKLLQGMWGGGEPNISHCVFYCGSGVTAAFSIAVAYHVGLGEPYLYAGSWSEYADTFNFTLARRIIKEHGLLISMVSSSLPYNMKATLNNVTLVVDGVVVNNPDEELKQALVHLHIGEKAHVTFKSQRQAVIEAHPRIDT
Protein: Ninein (E9PN67)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
Sequence:
MDEVEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQQTLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPDCSLEAQPKYVRGGKRYGRRSLPEFQESVEEFPEVTVIEPLDEEARPSHIPAGDCSEHWKTQRSEEYEAEGQLRFWNPDDLNASQSGSSPPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGTMSVEDFFYGLFKNGKSLTPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMTSTIGFRVFSCLDDGMGHASVERILDTWQEEGIENSQEILKALDFSLDGNINLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENELLENAEKLAEYENLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECNPLNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSETQQSLLSDQILELKSSHKRELREREEVLCQAGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIHKATCETADRERAEMSTEISRLQSKIKEMQQATSPLSMLQSGCQVIGEEEVEGDGALSLLQQGEQLLEENGDVLLSLQRAHEQAVKENVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEQFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKLKMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKIENEGLNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEIAWLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKLDEQLMENSVVGSSREGCSSLPEIVCEDAAPEVHCDA
Protein: Exostosin family protein (Glycosyltransferase) (F4HY10)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323}.
Interaction partners:
Sequence:
MASLTSNKPRNFGAYSHYATPCTRTHQIGALFLVVSTFFVTRLFDQWFSESNSVTPVIDLRRTSSSYGIKTDNGIIRWPERGYGSHLSLKIYVYDENEIDGLKELLYGRDGSVKTTACLKGQWGSQVKIHKLLLESKFRTIKKDEADLFFVPAYVKCVRMLGGLNDKEINQTYVKVLSQMPYFRRSGGRDHIFVFPSGAGAHLFRSWSTFINRSIILTPEADRTDKKDTTAFNSWKDIIIPGNVDDAMTKNGQPDVQPLPLSKRKYLANYLGRAQGKAGRLKLIDLSKQFPDKLECPDLKFSGTEKFGRTTYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDHAELPFQNVIDYAQVSIKWPSTRIGSEFLDYLASISDRDIEGMIARGRKIRCLFVYGPDSAPCSAVKGILWELQRKVRHFQQSTETFWLHNGSFVNRELVQFSSWRPPMPLP
Protein: Ornithine transcarbamylase, mitochondrial (OTCase) (EC 2.1.3.3) (Ornithine carbamoyltransferase, mitochondrial) (P11725)
Organism: Mus musculus (Mouse)
Function: Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:P00480}.
Interaction partners:
- Carbamoyl-phosphate synthase, mitochondrial
- Argininosuccinate synthase
- Argininosuccinate lyase
- Arginase-1
- Ornithine aminotransferase, mitochondrial
- Arginase-2, mitochondrial
- 1,4-alpha-glucan-branching enzyme
- N-acetylglutamate synthase, mitochondrial
- Aminoacylase-1
- Nitric oxide synthase 1
Sequence:
MLSNLRILLNNAALRKGHTSVVRHFWCGKPVQSQVQLKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPVLQKPKF
Protein: Uncharacterized protein PB1A10.05 (Q9HDY5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MKRQRPQDSMISVPLQNENSTTTPTKEVSHLNFPLKRPRLHSFVPTSKQAALSDITPDTPPAFKTPYSSLPYNLVPQNSSTSKKRPRAEDLLVIEPSQNSLVPSTQNNEWNEIARKRVSLESDHPDKSGQVIDLATGQILDKQTEDIDDDRNKSAVSKSLVRHPHRLKMLPFGIQSAHPYISSLNSNYPTTWHFASHYYPTDSKQLVKYHPTEVHPSWTVEEPVHYNTYDGVVNEPNSSVIIEELDDDYDELNDPMNNNDTPITNSTHSAQMSNLPTHDSMDIDMGGAVPSTST
Protein: Probable citrate synthase, mitochondrial (EC 2.3.3.16) (Protein knockdown) (Q9W401)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in controlling neuronal activity and seizure susceptibility.
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- Aconitate hydratase, mitochondrial
- Aconitate hydratase, mitochondrial
- ATP-citrate synthase
- Malate dehydrogenase, mitochondrial
- Malate dehydrogenase
- Isocitrate dehydrogenase
- Cytoplasmic aconitate hydratase
- Cytoplasmic aconitate hydratase
- Acetyl-coenzyme A synthetase
- Malate dehydrogenase
Sequence:
MSLYRISARKLSEAQKLPNVGAYVRMIAADGKSLRDVLAAKVPQEQERVKNFRKQHGATKMGETTIDMMYGGMRGIKALVTETSVLDADEGIRFRGLSIPECQKVLPAADGGTEPLPEGLFWLLLTGEVPTKSQVQQLSREWAERAALPQHVVTMLNNMPTTLHPMSQFAAAVTALNHDSKFAKAYSDGVHKSKYWEYVYEDSMDLIAKLPVVAATIYCNTYRGGKGSRSIDSSLDWSANFVKMLGYDNAPFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWLRKLQKEAGNNPSEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPEDETFQLVSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASLVWDRALGLPIERPKSFSTDLLVKMVQK