wanglab/gogpt-training-data huggingface dataset:
Protein: MALT1 paracaspase (A0A1D5P1T2)
Organism: Gallus gallus (Chicken)
Interaction partners:
- Caspase recruitment domain family member 9.
- Caspase recruitment domain-containing protein 11
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Caspase-8
- Mitogen-activated protein kinase 9
- Uncharacterized protein
- mitogen-activated protein kinase
- Mitogen-activated protein kinase.
- mitogen-activated protein kinase
- Mitogen-activated protein kinase.
Sequence:
MSEPPCSPPGSLPLSRLAEPLLRRLSELLDRAAPGKGWRELAQRAGSRGRVRLSPLDLEQCSLKVLEPEGSPSWSLLKLLGDRGCTVVELVEFLQAMEHTEALQCLSYSGIKIVVQPDSQAVLCGQVVKLCCWATGHPFVHYQWFKQKKEVPHGNSPELVLNPVKVNDAGFYICRVNSESSFTFSRWARLEVCDLQDTAHGSLISLPEKKLCICIQPQPQNLTVGDALVLECGAVGNPIPQYQWFRNGFPLANGNKNVYTVSCVDMEHGGTYWCHVFNDKEDQDSKKIEVIIGRKAMAVECTEEELSDLQKTDLQEQFSDRPFATDKVALLIGNMSYWNHPQLKAPMVDVYELTNLLRQLDFKVVSLLDLTESEMRNAVDEFLLLLDRGVYGLLYYAGHGYENYGNSFMVPIDAPNPYRSANCLCVQNILKLMQEKETGLNVFLLDMCRKRNEYDDTILILDALKVTANIVFGYATCQGAEAFEIQQLGLANGIFMKFLKERLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALSDPIQQTISSAESMARNLQWAKAHELPESMYLEFKCGVQIQLGFAAEFSNVMIIYTRIVKKPPEILVCRAYVTDFPLDLDVDPKEANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLIFTVCLHYEYPGIEDTMDERKEVNVGKPLIAKLGLHHGFRNNCLQTCCVANNLFHSQVESSPVVTKYYFPSRCQPNSCPGAYHPNCTCPGSTRQLEACSCSGTSRMLASRHEVQNYSPPAEKSNVPIETTDDTVELEFLLSDSLGLSKQQ
Protein: Histone H1 (P02255)
Organism: Drosophila melanogaster (Fruit fly)
Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H2A
- Protein suppressor of underreplication
- Histone-lysine N-methyltransferase Su
- High mobility group protein D
- CG3509 protein
- Histone H3
- Chromator, isoform A
- Histone H4
Sequence:
MSDSAVATSASPVAAPPATVEKKVVQKKASGSAGTKAKKASATPSHPPTQQMVDASIKNLKERGGSSLLAIKKYITATYKCDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLSASAKKEKDPKAKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAKAKDAKKTGIIKSKPAATKAKVTAAKPKAVVAKASKAKPAVSAKPKKTVKKASVSATAKKPKAKTTAAKK
Protein: Ureidoglycolate hydrolase (OsUAH) (EC 3.5.1.116) (Q2QMN7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in the catabolism of purine nucleotides. The sequential activity of AAH, UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea.
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8VXY9}.
Interaction partners:
- Probable
- Urease
- Os01g0574600 protein
- Gamma hydroxybutyrate dehydrogenase-like protein
- Alanine aminotransferase 2
- Isocitrate lyase
- glycerate dehydrogenase
- Peroxisomal
- Malate synthase
- alanine--glyoxylate transaminase
Sequence:
MATSAAARFLAALAGAAVLLVLLGGAAGAVVGHDDDAAAARRTMEEFAGFPASDYRGDGGGGSGGSSPFYVDSDGLQRQIDELASFSDSPVPSVTRVLYSDKDVQARRYIKGIMNQLGLSIREDAVGNIFGRWEGSEAGLGAVATGSHVDAIPFSGKYDGVVGVLGALEAIRMLKRSGFQPKRSLEVIMFTSEEPTRFGISCLGSRLMAGSEELARSLKETVDNQNVSFFDAADSAGYKMHPEELHNVFLKKDDYFAFVELHIEQGPILEKEGIKIGVVTAIAAPASIKVEFEGNGGHAGAVLMPARNDAGLAAAELALAVEKHVLESGSIDTVGTVGILQLHPGAINSIPSKSHVEIDVRDIDEKRRNNVIEKVHQSAIEISKNRGVLLSEFKIINQDPPALSDKSVISAMEFAAKQLNLEYKLMISRAYHDSLFMARISPMGMIFIPCYKGYSHKPEEYASPEDMANGVKVLALAMARLSLQ
Protein: tRNAHis guanylyltransferase catalytic domain-containing protein (Q54HW0)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSSSTIKKFLNSPTSLLSSKSLLIRSFSSQSNGNFRNYNKFELFEKAFDFVLPPYQPIIIRLDGNSFSKLNKQLKLERHDERFHESMKETSNNLFSHFIGCKFIYSFSDEINIVIYNQYPDNQFLSNRIQKLISTTSSITSLNFSINLSKKLNNNNNNNNVFSYFDCRAFVLPINEVKDYFIKRQGRCYTNFLSSIASDNGFNTDSIFNNDSGLDGSKKNIYAREYYLEKQGVNLMEIPEHFKSGFLVFKNSTNELDYKSPINFKSDTIIDYLLNRKN
Protein: Acyl-CoA desaturase (EC 1.14.19.1) (G8BCQ2)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Cytochrome b5 heme-binding domain-containing protein
- Very-long-chain 3-oxoacyl-CoA reductase
- Fatty acid desaturase domain-containing protein
- Elongation of fatty acids protein
- Elongation of fatty acids protein
- Very-long-chain
- IPT/TIG domain-containing protein
- Elongation of fatty acids protein
- Oleate-induced peroxisomal protein POX18
- Delta 8-
Sequence:
MTSTEQLETVEITKLNAIAAGTNKKVPRIVAAGLGGKLMGTADLVKVTAEEITQDSMESLAEKDAREKAEYANKKHISEEPWTRDNWAKKINWLNLILVAGVPAIGMGAAFTITPQFKTIVLAFILYVFSGVSITAGYHRLYAHKSYDAALPVRMFFAFFGAGAIEGSIKWWGHSHRVHHRYTDTPRDPYDARRGFWYSHMGWMLQKANPKNRARADISDLVADKVVVFQHKHYLLLMIFSAFVFPTLVAGYFWGDYWGGFIYGGVLKSFIIQQATFCVNSLAHWIGTQPFDDRRTPRDHVLTAFVTFGEGYHNFHHEFPSDYRNALKWYQYDPTKMVIYALSQLGLAWNLKKFSQNAIEQGLLQQQQKKLDRQRQKLNWGSSVEELPVWTREEFNARAKKEGLIIISGIIHNVKNFIKEHPGGQALIRATLGKDATDAFSGAVYRHSNAAHNILATMRVAVVKDVSVNANTFDAQEEFMAKEKQN
Protein: Uncharacterized oxidoreductase Rv2298 (EC 1.-.-.-) (P9WQA7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Putative L-lactate dehydrogenase
- Conserved protein
- Putative glyoxylase CFP32
Sequence:
MKYLDVDGIGQVSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGEALGDDRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQPNPVVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLRRIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQSRDALTDAARAFRPVSTGRFLTDMVREKVSRR
Protein: t-SNARE coiled-coil homology domain-containing protein (Q389Y1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Target SNARE, putative
Sequence:
MTERTDTIRELFHKSSPYRPGGDDFAELTALKSHTFYETFQVVTSTAKVAVRNTRASIKAALRAMEQFSPAVSDQESALLLQEAELLAASDAIKELIASLKNACVQSEKSGSRWGAAVSRKGDEAQDAKTGKPSNQMLLHLETALEVVGLCTGRWRLLLALCKEELILYKQEMFSFGRIGVLSCQDPVKEKCGDAESSISRREPDVERPQELDLPIGCSVEKPKDATQAVMSVVDRVMKEAARRVTVAPLPLNSGVWSKIRGNKSNCRNVWNADISEVPVPQFEYSLEEQQQLRVENAMLEKHQRLVSAEDAKAVEVSVRELSQLTSLISERVIQQNEQFSILLKNTEAAQNNMQRGIGEVKQTLTHFWNPTRQLIAVLWTSIIVLLLANWIIR
Protein: Triose phosphate/phosphate translocator TPT, chloroplastic (Protein ACCLIMATION OF PHOTOSYNTHESIS TO ENVIRONMENT 2) (Q9ZSR7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Triose phosphate/phosphate translocator that transports inorganic phosphate, 3-phosphoglycerate (3-PGA) and triose phosphate. Functions in the export of photoassimilates from chloroplasts during the day. In the light, triose phosphates are exported from the chloroplast stroma in counter exchange with inorganic phosphate (Pi), generated during sucrose biosynthesis in the cytosol. Involved in photosynthetic acclimation, a light response resulting in increased tolerance to high-intensity light.
Subcellular location: Plastid, chloroplast membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- At1g52870/F14G24_14 family protein)
- Maltose excess protein 1, chloroplastic
- Plastidic glucose transporter 4
- Homogentisate phytyltransferase 1, chloroplastic
- At3g13062
- Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic
Sequence:
MESRVLLRATANVVGIPKLRRPIGAIHRQFSTASSSSFSVKPIGGIGEGANLISGRQLRPILLLDSSAINGGEKREILKPVKAAAAEGGDTAGDAKVGFLAKYPWLVTGFFFFMWYFLNVIFNILNKKIYNYFPYPYFVSVIHLFVGVVYCLISWSVGLPKRAPIDSNLLKVLIPVAVCHALGHVTSNVSFAAVAVSFTHTIKALEPFFNAAASQFIMGQSIPITLWLSLAPVVLGVAMASLTELSFNWLGFISAMISNISFTYRSIFSKKAMTDMDSTNVYAYISIIALFVCIPPAIIVEGPKLLNHGFADAIAKVGMTKFISDLFWVGMFYHLYNQLATNTLERVAPLTHAVGNVLKRVFVIGFSIVIFGNKISTQTGIGTGIAIAGVAMYSIIKAKIEEEKRQGKKA
Protein: At5g38980 (Transmembrane protein) (Q8GXY9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Splicing factor YJU2
- Probable disease resistance protein RDL5
- Non-specific lipid transfer protein GPI-anchored 6
- Serine carboxypeptidase-like 43
- F3F9.4
- EP1-like glycoprotein 1
- Beta-glucosidase 26, peroxisomal
Sequence:
MKSIVFFFLLLLFAVATSDNVINGWYNLTAVHDDEVIWSSFAAPMMKGGSSYITYPVLRPQQACNPCSGAVKYAKKKNCLVYTRCKRFPKGM
Protein: Homoaconitase, mitochondrial (EC 4.2.1.36) (Homoaconitate hydratase) (P49367)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Homoisocitrate dehydrogenase, mitochondrial
- Homocitrate dehydratase, mitochondrial
- 3-isopropylmalate dehydrogenase
- Saccharopine dehydrogenase [NADP
- Lysine biosynthesis regulatory protein LYS14
- Saccharopine dehydrogenase [NAD
- Homocitrate synthase, cytosolic isozyme
- Homocitrate synthase, mitochondrial
- Citrate synthase, mitochondrial
- Citrate synthase 3, mitochondrial
Sequence:
MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Protein: Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (AtUBP6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Q949Y0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 11 homolog
- 26S proteasome regulatory subunit 6B homolog
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- 26S proteasome non-ATPase regulatory subunit 6 homolog
- 26S proteasome regulatory subunit RPN13
- 26S proteasome non-ATPase regulatory subunit 14 homolog
- Proteasome subunit beta type-1
- Proteasome subunit alpha type-5-A
- Proteasome subunit beta type-4
- 26S proteasome regulatory subunit 7 homolog A
Sequence:
MPTVSVKWQKKVLDGIEIDVSLPPYVFKAQLYDLTGVPPERQKIMVKGGLLKDDGDWAAIGVKDGQKLMMMGTADEIVKAPEKAIVFAEDLPEEALATNLGYSAGLVNLGNTCYMNSTVQCLKSVPELKSALSNYSLAARSNDVDQTSHMLTVATRELFGELDRSVNAVSPSQFWMVLRKKYPQFSQLQNGMHMQQDAEECWTQLLYTLSQSLKAPTSSEGADAVKALFGVNLQSRLHCQESGEESSETESVYSLKCHISHEVNHLHEGLKHGLKGELEKTSPALGRTALYVKESLIDSLPRYLTVQFVRFFWKRESNQKAKILRKVDYPLVLDIFDLCSEDLRKKLEAPRQKLREEEGKKLGLQTSAKSGSKDSDVKMTDAEASANGSGESSTVNPQEGTSSEKETHMTGIYDLVAVLTHKGRSADSGHYVAWVKQESGKWIQYDDDNPSMQREEDITKLSGGGDWHMAYITMYKARFVSM
Protein: Brevican core protein (Q61361)
Organism: Mus musculus (Mouse)
Function: May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}. Secreted {ECO:0000250|UniProtKB:Q96GW7}.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase zeta
- Aggrecan core protein
- Versican core protein
- Neurocan core protein
- A disintegrin and metalloproteinase with thrombospondin motifs 4
- A disintegrin and metalloproteinase with thrombospondin motifs 5
- Agrin
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
- Decorin
- Fibronectin
Sequence:
MIPLLLSLLAALVLTQAPAALADDLKEDSSEDRAFRVRIGATQLRGVLGGALAIPCHVHHLRPPHSRRAAPGFPRVKWTFLSGDREVEVLVARGLRVKVNEAYRFRVALPAYPASLTDVSLVLSELRPNDSGVYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFAGAQEACARIGARIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQNPREACSGDMDGYPGVRNYGVVGPDDLYDVYCYAEDLNGELFLGAPPSKLTWEEARDYCLERGAQIASTGQLYAAWNGGLDRCSPGWLADGSVRYPIITPSQRCGGGLPGVKTLFLFPNQTGFPSKQNRFNVYCFRDSAHPSASSEASSPASDGLEAIVTVTEKLEELQLPQEAMESESRGAIYSIPISEDGGGGSSTPEDPAEAPRTPLESETQSIAPPTESSEEEGVALEEEERFKDLEALEEEKEQEDLWVWPRELSSPLPTGSETEHSLSQVSPPAQAVLQLGASPSPGPPRVRGPPAETLLPPREGSPTSTPGGAREVGGETGSPELSGVPRESEEAGSSSLEDGPSLLPATWAPVGPRELETPSEEKSGRTVLAGTSVQAQPVLPTDSASHGGVAVAPSSGDCIPSPCHNGGTCLEEKEGFRCLCLPGYGGDLCDVGLHFCSPGWEAFQGACYKHFSTRRSWEEAESQCRALGAHLTSICTPEEQDFVNDRYREYQWIGLNDRTIEGDFLWSDGAPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPQLPLAQIFGRPRLRYAVDTVLRYRCRDGLAQRNLPLIRCQENGLWEAPQISCVPRRPGRALRSMDAPEGPRGQLSRHRKAPLTPPSSL
Protein: DNA-binding protein REB1 (QBP) (P21538)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymerase II. It is essential for cell growth. May stimulate or inhibit transcription. Specifically recognizes the sequence 5'-CCGGGTA-3' or 5'-CGGGTRR-3' (where R is any purine). A member of the general regulatory factors (GRFs) which act as genome partitioners. Acts as a chromatin insulator which are known as STARs (Subtelomeric anti-silencing region). STARs prevent negative or positive transcription influence by extending across chromatin to a promoter.
Subcellular location: Nucleus {ECO:0000305|PubMed:11258704}.
Interaction partners:
- ARS-binding factor 1
- Chromatin structure-remodeling complex protein RSC3
- Triosephosphate isomerase
- DNA-binding protein RAP1
- Chromatin structure-remodeling complex subunit RSC2
- TATA-binding protein-associated factor MOT1
- Centromere-binding protein 1
- RFX-like DNA-binding protein RFX1
- Protein TBF1
- Pheromone receptor transcription factor
Sequence:
MPSGHNDKNANQESVEEAVLKYVGVGLDHQNHDPQLHTKDLENKHSKKQNIVESSSDVDVNNNDDSNRNEDNNDDSENISALNANESSSNVDHANSNEQHNAVMDWYLRQTAHNQQDDEDDENNNNTDNGNDSNNHFSQSDIVVDDDDDKNKKDAGVGVDDDHQSMAMAAVAAAYTLSKNNNNNNSIANDSNSRKRQHDNGNNHENSQKKRKNNNDDDDRQIGNVDPELTTLGDADDNDTNNDVIDRDQLVHKAIIDADSITQHPDFQQYLNTAADTDDNEKLKHIKDHLMRTHGLNHQNKNHNDDTDDLSNSTKQYSELQKDSMLDSSLNKSRNYMEVLPKVISQDTQPHQQKSPSHDNEAGSVDNSEISQLLQSAATKASSLVSLSSSSATPSTSRSNNSKAFDKAEDAALERFINEYEAIERLTRQQVCERIWSSDRPKDNFWNNIYKVLPYRSSSSIYKHMRRKYHIFEQRGKWTAEEEQELAKLCAEKEGQWAEIGKTLGRMPEDCRDRWRNYVKCGTNRASNRWSVEEEELLKKVISDMLEEAQQQQSQLHPNLLEEEQHLLQDDQNDHRNNDEDDDDTASAAAAAAAAIQEQQQLLQQKQQDDDDAIAAAAAAASSSLGDNKDEDKPHDSLGIQLDDNSQNSMVPAPSATSTHSKSLSNTIRRHNNKLRKSLMGNGKLDFKDIINWTIVSERMGGTRSRIQCRYKWNKLVKREAIAKIQTVKDDDMLWIFEKLRDLGITEDSQVDWDELAALKPGMKLNGLELKLCYERMKKKVKGYKQKSINEISKELVDYFSSNISMKTEN
Protein: 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) (Acetolactate synthase-like protein) (IlvB-like protein) (Q6NV04)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A1L0T0}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- 2-oxoisovalerate dehydrogenase subunit alpha
- Citrate synthase, mitochondrial
- Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
- Leukocyte receptor cluster member 8 homolog
- Alcohol dehydrogenase iron-containing 1.
- Guanosine-3',5'-bis
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 2
- 2-iminobutanoate/2-iminopropanoate deaminase
- Cytochrome c oxidase subunit 3
Sequence:
MDISMYLGCSLGAALGGVIFASYKLGLLYQLFHKTERQSPRHGGESVAEVLRSHGVKFVFTLVGGHISPILVACEKLGIRIVDTRHEATAVFAADAVARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAESPLLLIGGAAATLLQGRGALQDIDQMSLFKPLCKFCASVRTVREIVPTVRKALAIAQSGTPGPVFIEFPIDTLYPYHVVEKEFAPKNTPKGLMGKIIAWYLKNHLSNLFAGAWESRDLSPLPVHIPHATDDQVQRCVELVSRAKKPVILLGSQATLPPTPADDIRKALESLGIPCFLGGMSRGLLGKNSPLHIRQNRRDALKDADLVLLAGTVCDFRLSYGRVLNRRSKIIAVNRDKSQLLKNSDMFWKPTVAIQGDAGSFLLNLSKALKGHRCPEEWPQSLKEGDNVKEKANRAKADEKTERHLNPLSVLHRVDELLAEDSIIVADGGDFVGSAAYIMRPRGPLCWLDPGAFGTLGVGGGFALGAKLCRPESEVWIVYGDGSLGYTVAEFDTFTRHKTPVIALVGNDACWSQISREQVPMLGSNVACGLAFTDYHVVADGYGGKGYLIGREDESQLEDIIKKAQKECKEGKAVLLNVLIGKTNFREGSISV
Protein: tRNA (cytosine(38)-C(5))-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2) (Q4G073)
Organism: Rattus norvegicus (Rat)
Function: Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O14717}.
Interaction partners:
- tRNA
- DNA
- DNA
- DNA
- DNA
- NOP2/Sun RNA methyltransferase 6
- NOP2/Sun RNA methyltransferase 3
- 5-cytosine rRNA methyltransferase NSUN4
- 28S rRNA
- NOP2/Sun RNA methyltransferase family member 7
Sequence:
MEPLRVLELYSGIGGMHHALRESRVPAHVVAAIDVSTVANEVYKHNFPHTHLLAKTIEGISLEEFDKLSFNMILMSPPCQPFTRIGLQGDMSDRRTNSFLYILDILPRLQKLPKYILLENVKGFEVSSTRGLLIQTMEACGFQYQEFLLSPSSLGIPNSRLRYFLIAKLQSEPLCFQAPGQILMEFPNSGTVQPQEYAVVEEGKLRVRTREPDVCLDSSSTQCSGQDSILFKHETAADIDRKRQQDSDLSVQMLKGFLEDGDTAQYLLPAKSLLRYALLLDIVKPTSRRSMCFTKGYGSYIEGTGSVLQTAEDVQIENIYKSLPDLPPEEKIAKLSMLKLRYFTPKEIANLLGFPPEFGFPEKTTVKQRYRLLGNSLNVHVVSKLLTVLCE
Protein: Beta-carotene isomerase D27, chloroplastic (EC 5.2.1.14) (Protein DWARF-27) (C7AU21)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in strigolactones biosynthesis by catalyzing the isomerization of the C9-C10 double bond in all-trans-beta-carotene leading to 9-cis-beta-carotene and providing the substrate for CCD7. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signals that stimulate hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:19470589}.
Interaction partners:
- Carotenoid cleavage dioxygenase 7, chloroplastic
- lycopene beta-cyclase
- Os02g0817900 protein
- beta-carotene 3-hydroxylase
- beta-carotene 3-hydroxylase
- beta-carotene 3-hydroxylase
- Carotenoid cleavage dioxygenase 8 homolog B, chloroplastic
- Strigolactone esterase D14
- Carotenoid cleavage dioxygenase 8 homolog A, chloroplastic
Sequence:
METTTLVLLLPHGGAGGVRPAAAATAKRSYVMRRCCSTVRAVMARPQEAPASAPAKKTETAAMMSTVQTETAAAPPATVYRDSWFDKLAIGYLSRNLQEASGLKNEKDGYESLIDAALAISRIFSLDKQSEIVTQALERALPSYILTMIKVMMPPSRFSREYFAAFTTIFFPWLVGPCEVMESEVEGRKEKNVVYIPKCRFLESTNCVGMCTNLCKIPCQKFIQDSLGMKVYMSPNFEDMSCEMIFGQQPPEDDPALKQPCFRTKCVAKQNHGVNCSI
Protein: Lipoprotein LprA (P9WK55)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages. Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs). Does not induce murine macrophage apoptosis or necrosis. Non-acylated protein does not act as a TLR2 agonist. Requires only host TLR2 as receptors to elicit host response in mouse, although TLR6 may play a redundant role, also requires CD14 and CD16 as accessory receptors.
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}. Note=May be shed from the cell surface in infected host cells. {ECO:0000305|PubMed:16785538}.
Interaction partners:
- Lipoprotein LpqH
- Phosphate-binding protein PstS 1
- Phosphate-binding protein PstS 2
- Lipoprotein LpqN
Sequence:
MKHPPCSVVAAATAILAVVLAIGGCSTEGDAGKASDTAATASNGDAAMLLKQATDAMRKVTGMHVRLAVTGDVPNLRVTKLEGDISNTPQTVATGSATLLVGNKSEDAKFVYVDGHLYSDLGQPGTYTDFGNGASIYNVSVLLDPNKGLANLLANLKDASVAGSQQADGVATTKITGNSSADDIATLAGSRLTSEDVKTVPTTVWIASDGSSHLVQIQIAPTKDTSVTLTMSDWGKQVTATKPV
Protein: 187-kDa microtubule-associated protein AIR9 (Auxin-induced in root cultures protein 9) (F4IIU4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Microtubule-associated protein that may be involved in the maturation of cell plates and proper insertion of cross-walls after cytokinesis.
Subcellular location: Cytoplasm, cell cortex {ECO:0000269|PubMed:17027491}. Cytoplasm, cytoskeleton, phragmoplast {ECO:0000269|PubMed:17027491}. Note=During interphase, binds cortical microtubules. In M-phase, locates to the preprophase band. During cytokinesis, binds the phragmoplast but not the forming cell plate at the midline, and at a later stage the cortical division site. After cell-plate insertion, enters the new cross-wall. {ECO:0000269|PubMed:25908862}.
Interaction partners:
- Kinesin-like protein KIN-14E
- Protein trichome birefringence-like 9
- CLIP-associated protein
- Microtubule-associated protein 70-4
- Major facilitator superfamily protein
- Pentatricopeptide repeat-containing protein At2g33680
- At4g28310
- Uncharacterized protein At5g64816
- Kinesin-like protein KIN-12C
- Kinesin-like protein KIN-UA
Sequence:
MEEVAAKVEEETVETNVDAVKEDNATIANESRSPESVSAVSVVSNRAASTKKKPVISSNLIKPTASSSLRVSGTTPVTIRRNSTGGVTENLAGTSKVLPKQVSTTASRTDPVRRSLPELRKSSVSSLSAKTVSKPSLSESKKSVPVSPGSRSLTKSTGFSLSKPESSARPAMSVSVSSKRAPSSSVDSSGSRTSSGRLHSTLTSGRTVSKVSSPSAGSSPSVSSSIRSKSFSSPLDRTSNFSGRKKTSTPESRDSRLIILPKVEVKAGDDMRLDLRGHRIRSLTSGGLHLSPNLEFVYLRDNLLSTLEGIEILNRVKVLDLSFNDFKGPGFEPLENCKMLQQLYLAGNQITSLASLPQLPNLEFLSVAQNKLKSLAMASQPRLQVLAASKNKITTLKDFPYLPVLEHLRVEENPLLKISHLEAASILLVGPTLKKFNDRDLSREEVAIAKRYPPQTALCLREGWEFCKSDLAAESTFRFLVERWKDTLPSGYLIKEAHVDRPSEEAPCQCHFGLFQESPTATDQELALKFQWSVADRSLSNFVPILNATKEVYWPKREDIGKILKIECTPVMAETEYPSIFAISSPVQRGKGIPKVVSLELNGELVEGNIIKGQAVVAWCGGTPGKCITSWLRRKWNGSPVVIDGAEDEEYMLSLDDVGSSMVFMYTPVTEGGARGEPQYKYTEFVKAAPPSVSNVRITGDAVEGCVLKGVGDYFGGKEGPSKFEWLRKNKETGELSLISAGTSEYTLTQEDVGTHVTFVYIPANFEGLEGEPVSTSSSVVKPAPPKVTDAKIVGDLRENSKVTVTGTVTGGTEGSSRVQWFKSSCSILEGDNSLEELSTSKVAKSFRIPLGAVGYYIVAKYTPMTPDGECGEPVYVLSERAVETLPPSLNFLSITGDNIEGGILTASYGYIGGHEGKSKYEWHYHKAENDLPGALIPEASGLLQYTITKEAIGKFISFQCIPVRDDGIVGEPRSCMSQERVRPGNPSTVSLHVVGALVEGTMLSAEKEYWGGEEGASVFRWFRTNSDGTPCEIKGATTSSYLLSVGDIGYFISVSYEPVRNDRARGPTAISEIAGPIVAGHPNCQSLEFLGSMIEGQRLSFVASYTGGMKGNCYLEWVRVKNNGVKEILSSDEFLDLSLDDVGESIELIYTPVREDGIEGSPRSIRTDGIAPANPMGLELLIPDCCEKQEVVPHKTYFGGHEGVGEYIWYRTKVKLHGSALTEISYAGEEVVVCCRTLKYTPSLEDVGAYLVLYWIPTRVDGRSGKPVVVITNSPVAPADPEVSNVRVKKLFSDAYSGEGEYFGGHEGPSLFSWYRENDGTIDLIDGANSKTYEVTESDYNCRILFGYTPVRSDSVVGELKMSEPTEIILPEVPKVDMLAFTGKAVQGDVLTAVQVIPKTEIQQLVWSKYKGDIQYQWFRSPESGDKISYEALSSEISCSYKVRFEDIGRCLKCECVVHDVFGRSSELAYAETDPISPGFPRIEKLEIEGQGFHTNLYAVRGNYFGGKEGKSKIQWLRSMVGSPDLISIPGETGRMYEANVDDVGYRLVVVYTPIREDGVQGHPVSASTEPVAVEPDILKEVRQKLETGLVKFEVLCDKDPYPKKIVGEGNLERRMLEMNRKRIKVVKPGSKTSFATTEVRGSYGPPFHVETFRNDQRRLRIVVDSENEVDIVVQSRHLRDVIVLVIRGFAQRFNSTSLNSLLKIDT
Protein: Gustatory receptor family protein 3 (O18280)
Organism: Caenorhabditis elegans
Function: Chemoreceptor involved in light-induced avoidance behavior. Probably acts as a molecular sensor in I2 pharyngeal neurons, required for the inhibition of feeding in response to light and hydrogen peroxide. Involved in circadian rhythms, probably by acting as a light sensor. In contrast to lite-1, does not act as a photoreceptor.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- G protein-coupled receptor
- Gustatory receptor
- Probable G-protein coupled receptor egl-47
- Peroxiredoxin prdx-2
- Serpentine receptor class r-10
Sequence:
MTITASNTLEFKWTSPRSSRSSFRTTTDAEQKISIDMSNTYCDQVLGPLYSYMMVLGLNHTHSSARNTMFKWPLTIYNYLTLAILTAATIRRISQIKQKSATNEEKDAAFHVLNPTFVLTLCHALLMFSGLAAGFLLLKLQKQREKMYHVLDQGLGRNRNEEHDSHHFKLNKLFISISFSFAAALSFVQIATKMRYLDLPDTPDLINRKIYFVILEGYVIFIASSCISLVAILFFQLCRILQFSIGQLIEEMVPKEKEECPLPEQSLQQIHDVQIHYQEISNAKLYIEQNFSFSLFYTYGCCIPLTCLLGYIAFRNGIQADMAETFSVAIWLTNTMLALMLFSIPAFMIAEEGDKLLTASFKMYHETLCEERDLLVLSQMSFLSFQMHATKLTLTAGNFFMMNRKIMISLFSAIFTYFLILVQFDAEKERAGECNNQSRVLIVQPPV
Protein: Lutropin subunit beta (Lutropin beta chain) (Luteinizing hormone subunit beta) (LH-B) (LSH-B) (LSH-beta) (P01229)
Organism: Homo sapiens (Human)
Function: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Subcellular location: Secreted.
Interaction partners:
- Glycoprotein hormones alpha chain
- Lutropin-choriogonadotropic hormone receptor
- Carbohydrate sulfotransferase 8
Sequence:
MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL