wanglab/gogpt-training-data huggingface dataset:
Protein: Mannose-6-phosphate isomerase (EC 5.3.1.8) (Q3ZB95)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Glucose-6-phosphate isomerase
- Glucose-6-phosphate isomerase
- Phosphomannomutase
- Phosphomannomutase
- Hexokinase-2
- Hexokinase 1.
- Hexokinase 2.
- glutamine--fructose-6-phosphate transaminase
- Glucosamine-6-phosphate isomerase
- Glutamine-fructose-6-phosphate transaminase 2.
Sequence:
MAEVKVFPLCCVVQNYAWGKAGLDSEVARLVLGGDPQAHIEHSKPYAELWMGAHPKGDALIKDNRISQRTLGQWIADFPGCLGSKVKDTFHGQLPFLFKVLSVNTALSIQAHPNRELAARLHAQFPEHYPDNNHKPEMAIALTQFEGLCGFRPMEEILGFLKNVPEFRALVGNEASEELQSADGNPHRTSLALKKCFTRMMNCEKKLFVDQLNMLVKRISEEEAAGKDTSGSNGELLLRLHSQYPGDIGCFSIYFLNRIVLQPGEAMFLGANEPHAYLSGDCVECMACSDNTVRAGLTPKYIDVDTLCEMLNYCPAPVSAKIFPCVRDNADPCVYLYDPPVPDFTVMRIQVPSSTQQYTVSALDSAGILLVIDGEAVATSAAALSDITLKRGSVLFISANESVSLQLTSSTGMTMFRACCLL
Protein: Cyclin-H1-1 (CycH1;1) (Q8W5S1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Associates with CDK-2 and CDK-3 and activates the CDK kinases.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16856985}. Nucleus {ECO:0000269|PubMed:16856985}.
Interaction partners:
- Cyclin-dependent kinase D-3
- Cyclin-dependent kinase D-2
- Pentatricopeptide repeat-containing protein At4g30825
- General transcription factor IIH subunit 2
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH subunit TFB2
- General transcription and DNA repair factor IIH subunit TFB4
- Cyclin-dependent kinase D-1
- General transcription and DNA repair factor IIH subunit TFB1-1
- General transcription and DNA repair factor IIH subunit TFB1-3
Sequence:
MADFQTSTQRAKWIFTPQKLAERYKAANQRAVQMLEKCGTTQVEVDASGSLTYPKDKVGSGDQADKKLKPLSADEERFMRAFYEAKVQEVCSAFAFPHKIQATALQYFKRFYLQWSVMQHHPKEIMLTCVYAACKIEENHVSAEEIGKGINQDHRIILKYEMAVLQSLEFDLIVYAPYRAIEGFVNNMEEFLQARDDEIQKLESLLKGATAEADKVMLTDAPLLFPPGQLALASLRIANGVLGVIDFDRYLENIVSQPNSEHTTSELTKLLDNIEYLVKNYKCPSEKDMKHINRKLKSCLGHSSSHDESKKREKRSKHKSHRSSNDTPNGAPPPIG
Protein: Oxysterol-binding protein-like protein 1 (O94512)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Probable ribosylation factor GTPase-activating protein cnt6
- Protein csx2
- Protein pob1
Sequence:
MPNPNQAIKKENEPIQVENPTELVRDDGEVEGYQKEEGKFKLVLSILKQCIGVKDIASLRFSLPAQLLEPVGNLEYWNYVDRPDYFAVMGDSDDELERMLGVLRWWFTKDLRFVRGRVVKPYNSVLGEFFRCKWVVTDPTVREDHTLDPDSSQLPTYKTEYSETTKFPLGKSYRPKASRTTSSQSVASTMTKSSTKTSKKKSSKKNSKSESNQDSSNDRSSTAPSTAESNNEHLSSSQKSKHSIVFMAEQTSHHPAVSAFYVTCPSKGIEVYGQDQIAVGFTGTSFKVCAGDLNKGVYVRFNKRDNEEYLCTHPSASVGGILRGNLHINLLDSTVILCPKTRIKTIITYIEERWLGKPRSLVEGVCYRYDPSNDTIDSIKAVPKENILATFKGNWRNCIFYSYAGESESRMLVDLNELDLVHKRCPPLDKQFPFESRKIWFPVTHNILAKHYTQATKAKQEIEDQQRQASAAREESHTEWKPRFFVPDEKEGRPTLTEEGKKVLEQSLSDEYIHGS
Protein: Nicotinic acetylcholine receptor alpha6, isoform B (Nicotinic acetylcholine receptor alpha6, isoform G) (Q7KTF9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MDSPLPASLSLFVLLIFLAIIKESCQGPHEKRLLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGSCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITNGEWYLLAMPGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKLTLGVTILLSLTVFLNLVAESMPTTSDAVPLIGTYFNCIMFMVASSVVLTVVVLNYHHRTADIHEMPPWIKSVFLQWLPWILRMGRPGRKITRKTILLSNRMKELELKERSSKSLLANVLDIDDDFRHTISGSQTAIGSSASFGRPTTVEEHHTAIGCNHKDLHLILKELQFITARMRKADDEAELIGDWKFAAMVVDRFCLIVFTLFTIIATVTVLLSAPHIIVQ
Protein: Origin of replication complex subunit 3 (AtORC3) (Q6E7H0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9UBD5}.
Interaction partners:
- Origin of replication complex subunit 5
- Origin of replication complex subunit 4
- Origin of replication complex subunit 1A
- Origin of replication complex subunit 1B
- Origin of replication complex subunit 6
- DNA replication licensing factor MCM5
- Origin of replication complex subunit 2
- Cell division control protein 6 homolog
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM7
Sequence:
MAPSGTVADPPQCSTTDSFNSSDTAENDIRPFFVLHKASSGNHNGKLTGIVKSKRRIESPSPKIAKRSEVESVEEEDGQFFSTLRFKVFETVWSKIEKTIEDVLRNSNSKVFSGIHDWIRESFESIISSGALKLSEAVRSYPVLTQASSKQLLTAMVLTRNLEMVDDLLTFEELELHLKSQGCHVAKLSSMDFSAKSGVGGCLRGLLRQFVMPTVDVADVTILASWYRENKNHENPVVIIVDDTERCCGPVLSDLILILSEWAIKVPIFLIMGVSTAHDAPRKILSVNALQRLCATRFTLSSPAERMDAVLKAVFLKPCSGFTVSHKVALFMRSYFLCQDGTLTSFVRTLKIACLQHFSLEPLSIMLEHFCHDGVNQLSGEGTELLTEATMKHAFDLPSVTRNKITRSTFEMLPHFLLDLQRMPNPWSIVVLCLYEAGKFDKLRLLDIFCEILDPEARYLKYFSPSEIVNSQSHNSGRNNVIRRVLRKLRDLSPSQLSSMLKSWENLTAEFTEINDKVIELHPFMRAVEAAGQRQGLPNSPKKHASRSNSKLEKELKAMTDKVATVIEFMLREYMKPVESVPFHEILCFKNVDKLQSALLGDPRGRIQLDLLESHDILHCVCCSQRGTTLLPSMHDTSILYKLAQEHADVINLHDWYQSFKTILIPRSSKAKQKSKSSSKSKKRKEICEEPEAPAEALIQARFCRAVMELQITGLIRMPSKRRPDFVQRVAFGS
Protein: Enamelin (O55196)
Organism: Mus musculus (Mouse)
Function: Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:O97939}.
Interaction partners:
- Ameloblastin
- Amelogenin, X isoform
- Amelotin
- Tuftelin
- Matrix metalloproteinase-20
- Kallikrein-4
- Odontogenic ameloblast-associated protein
- Protein FAM83H
- Kallikrein 1-related peptidase-like b4
- Pseudokinase FAM20A
Sequence:
MLLLQCRNPTSPPKPCGLVPNVKMSLLVFLGLLGVSAAMPFQMPMPRMPGFSSKSEEMMRYNQFNFMNAPPMMPMGPYGNGMPMPPHMPPQYPPYQMPMWPPPVPNGWQQPPMPNFPSKTDQTQETAKPNQTNPQEPQPQKQPLKEPPNEAARAKDDAQPPQPFPPFGNGLYPYPQPPWPIPQRGPPTAFGRPKFSNEEGNPYYAFFGYHGFGGRPYYSEEMFEDYEKPKEKDPPKPEDPPPDDPPPEASTNSTVPDANATQSIPEGGNDTSPIGNTGPGPNAGNNPTVQNGVFPPPKVNVSGQGVPKSQIPWRPSQPNIYENYPYPNYPSERQWQTTGTQGPRQNGPGYRNPQVERGPQWNSFAWEGKQATRPGNPTYGKPPSPTSGVNYAGNPVHFGRNLPGPNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPYVGANPASNKPFIGANPAANKPSIGTNPAANKPSIGTNPAANKPFVRNNVGANKPFVGTNPSSNQPFLRSNQASNKPFMRSNQASNKPFVGTNVASVGPKQVTVSHNMKTQNPKEKSLGQKERTVTPTKDASNPWRSAKQYGINNPNYNLPRSEGSMVGPNFNSFDQQENSYFSKGASKRVPSPNIQIQSQNLPKGIALEPRRTPFQSETKKPELKHGTHQPAYPKKIPSPTRKHFPAERNTWNRQKILPPLKEDYGRQDENLRHPSYGSRGNIFYHEYTNPYHNEKSQYIKSNPWDKSSPSTMMRPENPQYTMTSLDQKETEQYNEEDPIDPNEDESFPGQSRWGDEEMNFKGNPTVRQYEGEHYASTLAKEYLPYSLSNPPKPSEDFPYSEFYPWNPQETFPIYNPGPTIAPPVDPRSYYVNNAIGQEESTLFPSWTSWDHRNQAERQKESEPYFNRNVWDQSINLHKSNIPNHPYSTTSPARFPKDPTWFEGENLNYDLQITSLSPPEREQLAFPDFLPQSYPTGQNEAHLFHQSQRGSCCIGGSTGHKDNVLALQDYTSSYGLPPRKNQETSPVHTESSYIKYARPNVSPASILPSQRNISENKLTAESPNPSPFGDGVPTVRKNTPYSGKNQLETGIVAFSEASSSQPKNTPCLKSDLGGDRRDVLKQFFEGSQLSERTAGLTPEQLVIGIPDKGSGPDSIQSEVQGKEGEMQQQRPPTIMKLPCFGSNSKFHSSTTGPPINNRRPTLLNGALSTPTESPNTLVGLATREQLKSINVDKLNADEHTTLESFQGTSPQDQGCLLLQA
Protein: Hdac6 protein (A7YT55)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
LHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGGPLSEVSPLPAPVCAEVKVSSPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSLPSPKPKGKCTPGGKGKKSPRQSTPSQSPGQATHRPDQSGFDELTADLLSLNLNTSTSSNTSPESVAVGGARRKVKPNTHRVSAGLESESPLKLNPEKAGAGDDTDVKAETPNRSISEPVVTCDSSAVKDQESLVLEAAGGNTVQSVLERVFGAQATDVDTMYVVDPLPWCPHLESVRPVPAGGIDVFQPCEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACESYVHNKVLHEAKNAAHLVKFGEGIHPFN
Protein: Transcription factor TGA2 (HBP-1b homolog) (AHBP-1b) (bZIP transcription factor 20) (AtbZIP20) (P43273)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Required to induce the systemic acquired resistance (SAR) via the regulation of pathogenesis-related genes expression. Binding to the as-1 element of PR-1 promoter is salicylic acid-inducible and mediated by NPR1. Could also bind to the C-boxes (5'-ATGACGTCAT-3') with high affinity.
Subcellular location: Nucleus.
Interaction partners:
- Regulatory protein NPR1
- Regulatory protein NPR3
- Regulatory protein NPR4
- Glutaredoxin-C7
- Glutaredoxin-C9
- Scarecrow-like protein 14
- Protein NIM1-INTERACTING 1
- DEAD-box ATP-dependent RNA helicase 36
- Protein NUCLEOLAR FACTOR 1
- Pre-mRNA-splicing factor SYF2
Sequence:
MADTSPRTDVSTDDDTDHPDLGSEGALVNTAASDSSDRSKGKMDQKTLRRLAQNREAARKSRLRKKAYVQQLENSRLKLTQLEQELQRARQQGVFISGTGDQAHSTGGNGALAFDAEHSRWLEEKNKQMNELRSALNAHAGDSELRIIVDGVMAHYEELFRIKSNAAKNDVFHLLSGMWKTPAERCFLWLGGFRSSELLKLLANQLEPMTERQLMGINNLQQTSQQAEDALSQGMESLQQSLADTLSSGTLGSSSSGNVASYMGQMAMAMGKLGTLEGFIRQADNLRLQTLQQMIRVLTTRQSARALLAIHDYFSRLRALSSLWLARPRE
Protein: Protein PRY1 (Pathogenesis-related protein 1) (P47032)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Secreted protein required for efficient export of lipids such as acetylated sterols. Acts in detoxification of hydrophobic compounds.
Subcellular location: Secreted {ECO:0000269|PubMed:11935221, ECO:0000269|PubMed:23027975}.
Interaction partners:
- Oxysterol-binding protein homolog 4
- Membrane-anchored lipid-binding protein YSP2
Sequence:
MKLSKLSILTSALATSALAAPAVVTVTEHAHEAAVVTVQGVVYVENGQTRTTYETLAPASTATPTSTATALVAPPVAPSSASSNSDVVLSALKNLASVWGKTTDSTTTLTSSESTSQSLAQATTTSTPAAASTTSTPAATTTTSQAAATSSASSSDSDLSDFASSVLAEHNKKRALHKDTPALSWSDTLASYAQDYADNYDCSGTLTHSGGPYGENLALGYDGPAAVDAWYNEISNYDFSNPGFSSNTGHFTQVVWKSTTQVGCGIKTCGGAWGDYVICSYDPAGNYEGEYADNVEPLA
Protein: Lactose phosphotransferase system repressor (P0A0Q0)
Organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)
Function: Repressor of the lactose catabolism operon. Galactose-6-phosphate is the inducer.
Interaction partners:
- Tagatose-6-phosphate kinase
- Galactose-6-phosphate isomerase subunit LacB
- Galactose-6-phosphate isomerase subunit LacA
- Tagatose-6-phosphate kinase
- Fructose specific permease, putative
- Tagatose 1,6-diphosphate aldolase
- PTS system, fructose-specific IIABC component, putative
- PTS system lactose-specific EIICB component
Sequence:
MNKHERLDEIAKLVNKKGTIRTNEIVEGLNVSDMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRFIAKKAASLIEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMRHITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYLLIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Q387M6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Polyubiquitin, putative
- Ubiquitin, putative
- NEDD8-activating enzyme E1 catalytic subunit
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin/ribosomal protein S27a, putative
- Ubiquitin-like protein, putative
- Proteasome subunit beta
- Proteasome subunit alpha type
- Proteasome regulatory non-ATPase subunit 8
- Proteasome subunit alpha type
Sequence:
MTKTWLPLESNPDVLNEYLKSLGLTNPKVAFNDVFGLDAELLAMVPRPIYAMILLYPLSDGMESGDAAACLKQKSEIEQFMTTNKFFYSKQTISNACGTMAVLHAVLNNTDVVGDMLEGSPIATLLWSTKDKSPEENAKLIESDSLLDQAHALASASGVTDNQPLDADIDLHFTCFVKIGDRCVELDGRKPHPLLHGHCVDEESFVKSCVDAIKEKMGRDPQSPRFNIIALCESRE
Protein: Autophagy protein 16 (Cytoplasm to vacuole targeting protein 11) (SAP18 homolog) (Q03818)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS). Recruits also ATG3 to the PAS. Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.
Subcellular location: Preautophagosomal structure membrane {ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:18077553, ECO:0000269|PubMed:20154084, ECO:0000269|PubMed:23064152}; Peripheral membrane protein {ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:18077553, ECO:0000269|PubMed:20154084, ECO:0000269|PubMed:23064152}.
Interaction partners:
- Autophagy-related protein 3
- Serine/threonine-protein kinase ATG1
- Autophagy protein 5
- Ubiquitin-like protein ATG12
- Autophagy-related protein 18
- Ubiquitin-like modifier-activating enzyme ATG7
- Putative lipase ATG15
- Autophagy-related protein 21
- Autophagy-related protein 8
- Ubiquitin-like-conjugating enzyme ATG10
Sequence:
MGNFIITERKKAKEERSNPQTDSMDDLLIRRLTDRNDKEAHLNELFQDNSGAIGGNIVSHDDALLNTLAILQKELKSKEQEIRRLKEVIALKNKNTERLNDELISGTIENNVLQQKLSDLKKEHSQLVARWLKKTEKETEAMNSEIDGTK
Protein: Platelet glycoprotein 4 (Glycoprotein IIIb) (PAS IV) (PAS-4) (Platelet glycoprotein IV) (A4D1B1)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
Interaction partners:
Sequence:
MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLWGYRDPFLSLVPYPVTTTVGLFYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFMISYCACRSKTIK
Protein: AT17695p (Q8T448)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MENPINFKDIPSEMPQPKRIQLEGETSVAEAINFLKTQCDTRKEHKPEEFQQDGPTVADELNARLAMVHVRETRAKRIRRLVKFSPNETQALYRFICVCPRYHPCYVPCQHTGQIIIDRDVLSREEHICFLATPKKDFSSPQLAKQARYYTKKIYVNQCTARVERLADPHPMRVSDTYNFFKDYLSPRHIAALENQMKPKPPVEAMSMEKALEYMEEEMRQRKAAKRVQKRRCKGLKKTNHFAPAQADAKDNLRTVRGNEGLSTQRSVYC
Protein: Cadherin-5 (Vascular endothelial cadherin) (Q8WNW5)
Organism: Sus scrofa (Pig)
Subcellular location: Cell junction, adherens junction {ECO:0000256|ARBA:ARBA00004536}. Cell membrane {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}.
Interaction partners:
Sequence:
MQVLVMLLAAAGTYLGLLTAATAASNPGRQDTPSTLPLHRRQKRDWIWNQMHIDEEKNGSLPHYVGKIKSSVNHKNTKYQLKGESAGKVFRVDENTGDVYAFERLDREKIPEYQLVALVVDKNTEKNLESPSSFTIKVHDINDNWPVFTQLVFNASVPEMSVIGTSVIQLTAVDADDPTVADHASVIYRLKEGEEHFRIRGPGLIETASKNLDRETVPMYKIVVETQDAQGLRGDSGTATVFITLQDVNDNFPVFTQTRYTFSVPEDIRVGSPLGSLFVKDPDEPQNRKTKYSIVQGEYRDTFTIEPDPTRNEGIIKPMKPLDYERIQQYSFTIEATDPTIDLRYLSGTSTKNIARVIINVTDVDEPPNFKQPFYHFQLRENEKKPWIGSVLAVDPDAAQRSIGYSIRRTSDKGQFFGINKHGNIYNVKELDREVYPWYNLTVEAKELDSRGTPTGKESIVQVHIEVLDENDNAPEFAKPYEAKVCEDAPQGKLVVQISAIDKDVTPRDVKFKFSLSTEDSNFTLTDNHDNTANITVKHGYFDRERAKVHHLPILISDNGRPSLTGTSTLHVTVCKCNERGEFTLCEEMGAQVGVSIQALVAIFLCILTIAVISLLVYLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRHGGAKPPRPALDARPSLYAQVQKPPRHAPGAHAPGEMAAMIEVKKDEADHDGGGPPYDTLHIYGYEGAESIAESLSSLGTDSSDSDIDYDFLNDWGPRFKMLAELYGSDPREELLY
Protein: Aspartic proteinase, putative (EC 3.4.23.40) (B9RXH6)
Organism: Ricinus communis (Castor bean)
Interaction partners:
Sequence:
MGTNFKPLVLFLFLSSLLSSLVSSAPNDGLVRLGLKKMKLDENSRLAARLESKNAEALRASVRKYGLRGDSKDTDIVALKNYLDAQYYGEIGIGTPPQKFTVVFDTGSSNLWVPSSKCIFSVACFFHSRYKSGQSSTYKKNGKSAEIHYGSGAISGFFSSDNVVVGNLVVKDQEFIEATKEPGVTFVAAKFDGILGLGFQEISVGNAVPVWYNMIKQGLIKEPVFSFWLNRNTQGEEGGEIVFGGVDLNHYKGKHTYVPVTQKGYWQFEMGDVLIGHKPTEYCAGGCSAIADSGTSLLAGPTTVVTLINEAIGATGVASQECKTVIAQYGETIMDLLIAEAQPKKICSQIGLCTFDGTRGVSMGIQSVVDDNNDKSSGIVRDAMCSACEMTVVWMQNQLRENQTQDRILNYVNELCDRIPNPLGESIVDCGSISSMPVVSFTIGGKVFDLSPQEYILKVGEGAQAQCISGFMALDVPPPRGPLWILGDIFMGRYHTVFDYGNLRVGFAEAA
Protein: Two-component sensor histidine kinase (I1SBA9)
Organism: Clostridium perfringens (strain 13 / Type A)
Interaction partners:
- Stage 0 sporulation protein A homolog
Sequence:
MLMNQMFWDFMENASMIIEWVSFYLIISQFSPKKRKNKQEVYSFIVIIIFSVLLKVLNVYPNERIVICFFIGLIYYKFNFRVNNIKCIMISLIFWLFMLTVEALSISFIVKINSLVNVSDLLGKNIYRMETMILSKVILISLIMVVRCLKFRVDIGKGDFIYILTPIATNIIIILVIFGYAFKGGREGFGDNVSIFFVSILLLLSNMSLMFIVSKIIKNNKLKLENEFIKDKLEMEYKYYSNLKDNQEKVKRLYHDIKNHIACIEGNNKETGIRKKYIDSLNSEIDKLNLGFNTGNEVLDVILNNKREKCMENNISLKVFIDFSKVNFIEYFDICTIFSNCIDNAIEACKKIKDNNRYISLKGNCVNNFYVIKIENSKTNKIKKLNGDFLTDKKDKFLHGIGLKNIRLALEKYNGEIIIEPLDDKFILKMLIPINQEKEA
Protein: Protein glass (P13360)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor required for gene expression specific to photoreceptor cells.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein PIP82
- FI01102p
Sequence:
MGLLYKGSKLLNTILDSLEDQEGGAMYISCDVSNGGPVEPETGYVPNNPLFGLALDSPQQECAASCVGCLSCQGSTALPISSLTSSDFDCGGCFDPTIGVGVGIGGGHIQISTTPPASSGNGSSNNGAGGGSSGNHGYWSTDEMASTFPGLPPLDIDPLPSLFPFSPCGASYNFAAGNPHQAASLSYTVHPHQMLISPNSHNHGQMHSQHQQHQHQQSQVQASHVGNSLLQSSGGNNIGSNGSAGGVANAASCYYETSAGTAAPPPPPAAAMYPSMSVNVSMNMTMHHGYGAGDAGGVPMQCSQMNWTPPSNSTSAAAAAAAVNVLYPPLLSPGHYPASATYSFTADFRAPAPTGLGALPPLTVGEKESPSPPANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLSLSAFEDEEDSNEDLDGDEGSSGGEMKPNLCRLCGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQAANLTAHVRTHTGQKPFRCPICDRRFSQSSSVTTHMRTHSGERPYRCSSCKKSFSDSSTLTKHLRIHSGEKPYQCKLCLLRFSQSGNLNRHMRVHGNNNSSNGSNGATGVGGESSTGSGVGGGNSLLT
Protein: GM14040p (Q8MZI0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLYDKLMAKCVASSRCDSALKVVAQRLLICLGDLTRYRVNHVKATDYMEAARYYQRAQELVPGNGAPFNQLAVISIYHHKRFDAVYYYVRSLLTSNSIQSAKESLLDLFDEIRRKYEETEMKQSPMHYAAGSKNQKSKQMRKEVWIYPDGIRRLHRTDDKGNKAKGNKATMAEVNRYEEMPPEEILPRIVSLYLYLLGKLYTGTDVDSLYPLLRKLQIQIGVALRHENLLSRSKLLKIVALNLFVVEHNKPKTSRREMRYHSFNFANSFFGLMMKKTNQLLAGFVEDSTNVQCLPEEDFATVNTYLQFVNVYVRWLSISLDVWEPVRSEEHSFIDCWAELTILFEYIECLMGKHKLEKNEILLDEDVALRGFTPLGRETLSMDYLKRGSERLQFFERVRRIGQFQEYYVQHQEALQQPLESSFTVEHLNAAMKNALENYDAESCGLAANVSKIQCKAVEELLCRSTDSDVSELCKLKKELEAKARVKQICTSKLEDILKFVDTKIYIEVRPRYLLPDTNCFIDCLEDFEKLSTEFKRYTLIIPLTVVKELDGLSKGVKLDSYRSSKQTQRIHHFDEVSSRAKKSLEFIKSAKGNVKCATTKGSFVNASVFALVEEEYLSNDDKILATAMAVSKTAKTEQCTDGKCFIQTELVLITTDRNLRAKALSRNLAVSALDEFLQWAKDCREST
Protein: Antitoxin ParD (P22995)
Organism: Escherichia coli
Function: Antitoxin component of a type II toxin-antitoxin (TA) system involved in plasmid partition. Inhibits the anti-DNA gyrase activity of toxin ParE; reverses and restores gyrase catalytic activity in vitro. The parDE operon alone is capable of stabilizing an RK2-derived minireplicon under defined growth conditions in several different Gram-negative bacteria. It does so by the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system. Binds its own promoter, autorepressing it; gentically only ParD is required for full autorepression.
Interaction partners:
Sequence:
MSRLTIDMTDQQHQSLKALAALQGKTIKQYALERLFPGDADADQAWQELKTMLGNRINDGLAGKVSTKSVGEILDEELSGDRA
Protein: Transmembrane protein (Q86I19)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MILRNLNPKFITTLFLLIVLLLNENVVFSQQPQYTCSEMEEPIVGDWGFSVIASSHPNISATSPWKATSSVSFCTDDMCGSSAYSLAGYYYAQFLYNESDPNTQTSTLWQTVSLPPILPNEQYYLEYFLSSQFETNINPVLNVYVDNRPVASYNGNLLLGDLERVPLESFLPSTVNIAFTTSYTNNGGGGGGGGGTSQSGFRIGSVIIRKPAATMPEEVYVDVAKGSDKYGNGTSVAPFSTIQQALNSVDFNGTIYLADGTYCNLASYLPISRSINIISQSGDPTKCILSGEYQLNLFKISYSNQPQDLFLTSPSRRGRFRQMESYFDISSNLITSSISGSGGSSGGDSSSSSSSSGSESGSDSSSSPDSKSININVKGITVGYAYSSDNSPGGAALFIEGNVVASFSNCIFTSNADSQNRGSISARGNAALILENTLVQNCSCSKVASFGPAISMLGFGGSPTISLVNCTMTENLYNILVDETSDFNMQDSNIQGIEPIEGASLCSIMLSRTQSSTINNCDIGGINNGALCIISSTSNISNTNFQGNNLKSGPGGNIYISQGSSVTIQNVVIEDSNGNIGAAIFAMELSKVNIFNTIIRNIGITNSLISSSDSDLVLSQSSIYNTSNDYTIYLFFGSFKLFDSNITNSKGSFYATQTVISISSTLFDDISIGSHVFQDCQVEIIDSIFSNLNGFFYSSFSKIHIVGSLIENSITQFLMISPLSNVLIENSVFSSNTDTIINLLSQSNLTVINSKFIDNFSNTSTNSILTQYEGSTSTFKNVLFQNNRSPGILGGCIFTFSSVVLDNCTAIGNFAKQGGVISTTIAGNLITIDGGIYQNNSASGGGGVIFYSSTPGPTIKNNAIFSGNTASYGNNTATDAALIDVEDPFPSSFRSGQDTYSGRIYIKDEEGQIVSGFEVKIFLQISGNTIDSTSTYNGIAIFSNTTLYGPINTTVDVEFLSNNPNLPVNQTVSNVLKCSPGQIPSTTKIECTECRTGSYGYNGETCVQCPSIHAYCPGGAKVNQFEGWWYDVNQTDKPYVLYECPNVNCIGSNTSDMCAPYSFGPLCAQCDPGYYDWGEGCKRCDKTSPILFIAIVAVSIGMIVLVQSSDSESGLMTVIIYFAQTLMVLSTGVKFNFLALLNLEFQPGGSSSIFGICPGPFDYYQQHYFTLLSAPWLIVVLLISTVFFYIVYRYKLIQKLKNKIIKEQEDIEKSKSISNYSSIIVTSDPGTINNSSLQKSLERKSLLRKQQQQQQPLLENDDDDSFDSTNTTTNDGDLSRDGYSTIADGGKHSILGKSIETSISGSLSSQVTLIDNATAIPSNQTFLSQQLGAFIKLMLNIYTPIGKATFELFFCENVGVSAYVLIANNGVSCYTDQYHKALMVSYCLLIVIIGFPLILMILLFLNRKSLDDPHTQRTYGVFILKYKSSFYFWDVILLLRRLLIILMSTMDPTSAARSFLLVVVSLVSVLLQLKYQPFKRISDNRLELTSLSLLFICCVYLDNTVYQSIEQWIVISSSIIFFLHAVYILYSNYRYQIIDSLQHYLYIISRGKKGRKNSNTTLFGSNSYFLYNQDHIYNDDDFSRDSGIFSKKDKKQSRTDKIVKKSKINNNNENNIENNNENNENNENNNNNVKEIEKILEEESKTNFEELNNNYYDDSDDFDEDESSDDEEDDETNGESTNLLKP
Protein: Putative inactive beta-glucuronidase-like protein SMA3 (Q15486)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDRSNPVKPALDYFSNRLVNYQISVKCSNQFKLEVCLLNAENKVVDNQAGTQGQLKVLGANLWWPYLMHEHPASLYSWEDGDCSHQSLGPLPACDLCDQLHLRSRQGGSVCGCDPCEQLLLLVSQLRAPGVDSAAAGRPV
Protein: Programmed cell death protein 10 (Cerebral cavernous malformations 3 protein) (TF-1 cell apoptosis-related protein 15) (Q9BUL8)
Organism: Homo sapiens (Human)
Function: Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity).
Subcellular location: Cytoplasm {ECO:0000305|PubMed:18782753}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q6NX65}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q6NX65}; Cytoplasmic side {ECO:0000250|UniProtKB:Q6NX65}. Cell membrane {ECO:0000250|UniProtKB:Q6NX65}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q6NX65}; Cytoplasmic side {ECO:0000250|UniProtKB:Q6NX65}.
Interaction partners:
- Striatin-interacting protein 1
- Striatin-3
- Serine/threonine-protein kinase 24
- MOB-like protein phocein
- Striatin
- Serine/threonine-protein kinase 26
- Striatin-4
- Cerebral cavernous malformations 2 protein
- Serine/threonine-protein kinase 25
- Sarcolemmal membrane-associated protein
Sequence:
MRMTMEEMKNEAETTSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKTVA
Protein: Helix-loop-helix protein 10 (Q23579)
Organism: Caenorhabditis elegans
Function: Probable transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3'.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:19632181}. Cytoplasm {ECO:0000269|PubMed:19632181}.
Interaction partners:
- Helix-loop-helix protein 4
- Helix-loop-helix protein hlh-2
Sequence:
MESSSMTTHQEEPLDLSTGNHGNSELSDEQQIMQVMESCGMFLQQNLFAWFLQSMLEASASQPQLTQDEPPENDTKENDLVKQNKSEVNDENESTPSPTQNSRRRTSTGKIDRRMVGKMCTRRYEANARERNRVQQLSKMFDQLRVCLPIEDDAKISKLATLKVASSYIGYLGAILQENSNDEEEFKKQLQVELECAKTLRK
Protein: Chaperone protein DNAJ, putative (Q57VJ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKPIPVAMNRSVRRAALMTLQPLVCSGTSARCITTGENHSFRPGRVTLFLRSLFVALTPQRLRSRMATGMQRGMERVQILEQEQLWLQRHGSPLRILGLPDHAELPEVRARYRELVLETHPDSQQRVEAVSGNGTERYDMIQTAYAMATNPTSLWHQNGAAPTLRRGLASGNSASLHVTLFAVMSYVMMGLVAVIFSLVVVRHLLEGALRLLDPKFYAFMTQQEEEERRRQLAGEVVDTDPKRLAPTVVKRLLFPGRFVHGGGSGDDFGYNNISESTGGNSPAD