wanglab/gogpt-training-data huggingface dataset:
Protein: EGFR adapter protein (Q6NR09)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the negative regulation of the Egfr/Ras signaling pathway. During wing morphogenesis, may function redundantly with PVRAP to inhibit Egfr activity and prevent uncontrolled cell growth.
Interaction partners:
Sequence:
MIMQDIRLRLEPQHSKATFISSSSASSSSSQTAETTLIETAEKSPASEAAAGTVTTTSPQHFFHHHHPPAHPHPPRQQPHPHSHSHPHPHPQLQRRPVEQLHLLHSHHDVQELSGQEHPHPQPGSHPHPHHLRSPSSEEDNSPTEMNNCRRLVDKPPLVKRLTMGIGLLRGTEDSRPLMHSTCGSSLTSGSGCGSTQTISDGYVNEAICEPDKYVASKFGDSCRQSLSALESATQRLQVELPAASKKYLRETCSANSSPKLFPGHSALRLDNLSLAEQQELKGAAWFQAGIPREISLEALSRQSPGAFLVRQSSTKPGCFALSLRVPPPSPRVAHYLILRTQRGYKIKGFTKEFSSLKALITHHSVMPELLPVPLTLPRPPSTRSQRSQGAYAGGTGNGGADFEMYGSLNDFRKMMADLNV
Protein: Myrosinase 1 (EC 3.2.1.147) (Beta-glucosidase 38) (AtBGLU38) (EC 3.2.1.21) (Sinigrinase 1) (Thioglucosidase 1) (P37702)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Degradation of glucosinolates (glucose residue linked by a thioglucoside bound to an amino acid derivative) to glucose, sulfate and any of the products: thiocyanates, isothiocyanates, nitriles, epithionitriles or oxazolidine-2-thiones. These toxic degradation products can deter insect herbivores. Seems to function in abscisic acid (ABA) and methyl jasmonate (MeJA) signaling in guard cells. Functionally redundant with TGG2. Hydrolyzes sinigrin and, with lower efficiency, p-nitrophenyl beta-D-glucoside.
Subcellular location: Vacuole {ECO:0000250}.
Interaction partners:
- Cytosolic sulfotransferase 16
- Nitrilase 1
- Indoleacetaldoxime dehydratase
- Cytochrome P450 71A12
- Nitrilase 2
- Nitrilase 3
- Cytochrome P450 71A18
- N-
- GDSL esterase/lipase ESM1
- Transcription factor MYB28
Sequence:
MKLLMLAFVFLLALATCKGDEFVCEENEPFTCNQTKLFNSGNFEKGFIFGVASSAYQVEGGRGRGLNVWDSFTHRFPEKGGADLGNGDTTCDSYTLWQKDIDVMDELNSTGYRFSIAWSRLLPKGKRSRGVNPGAIKYYNGLIDGLVAKNMTPFVTLFHWDLPQTLQDEYNGFLNKTIVDDFKDYADLCFELFGDRVKNWITINQLYTVPTRGYALGTDAPGRCSPKIDVRCPGGNSSTEPYIVAHNQLLAHAAAVDVYRTKYKDDQKGMIGPVMITRWFLPFDHSQESKDATERAKIFFHGWFMGPLTEGKYPDIMREYVGDRLPEFSETEAALVKGSYDFLGLNYYVTQYAQNNQTIVPSDVHTALMDSRTTLTSKNATGHAPGPPFNAASYYYPKGIYYVMDYFKTTYGDPLIYVTENGFSTPGDEDFEKATADYKRIDYLCSHLCFLSKVIKEKNVNVKGYFAWSLGDNYEFCNGFTVRFGLSYVDFANITGDRDLKASGKWFQKFINVTDEDSTNQDLLRSSVSSKNRDRKSLADA
Protein: Glycogen synthase kinase-3 beta (EC 2.7.11.26) (A0A0D9R447)
Organism: Chlorocebus sabaeus (Green monkey) (Simia sabaea)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Catenin beta 1
- Axin-1
- Adenomatous polyposis coli protein
- Axin 2
- FRAT regulator of WNT signaling pathway 1
- RAC-alpha serine/threonine-protein kinase
- Microtubule-associated protein
- APC regulator of WNT signaling pathway 2
- Beta-transducin repeat containing E3 ubiquitin protein ligase
- Dishevelled segment polarity protein 1
Sequence:
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST
Protein: 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial (EC 3.6.1.-) (GTP-binding protein 3) (tRNA modification GTPase GTPBP3, mitochondrial) (Q501Z5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q969Y2}.
Interaction partners:
- Mitochondrial tRNA translation optimization 1
- Mitochondrial tRNA-specific 2-thiouridylase 1
- GTP-binding protein 8
- Endoplasmic reticulum-Golgi intermediate compartment protein 2
- Endoplasmic reticulum-Golgi intermediate compartment protein 1
- Endoplasmic reticulum-Golgi intermediate compartment protein
- Endoplasmic reticulum-Golgi intermediate compartment protein 3
- G-2 and S-phase-expressed 1
- Large ribosomal subunit protein bL21m
- Mitochondrial ribosomal protein L13
Sequence:
MHFISCCLRRSTVSIAVSRSLLVKRLFCSGWPGDDTIYSLSSGQGKCGVAVVRVSGPASALAVRRLTRSLPAPRTASLRSISHPQSKELLDRGLVLWFPGPASFTGEDSAEFHIHGGPAVISGVLQALGSLPGLRPAEAGEFTRRAFYAGKLDLTEVEGLSDLIHAETEAQRRQALRQMAGDLGRIYQDWTDQLKRCLAHVEAFIDFSEDELIEDGVLNDVDRAVQQLQTDMENHLSDERRGERLRSGVHVVIAGSTNAGKSSLLNLLTQRPAAIVSPTAGTTRDVLEVPLDIGGYPVLLSDTAGLRDTSDSVEQEGVRRARQRVEQADLSLVVVDLTQLPSERRHVPVFLRGHLKNILERSSQQQQHILILNESDLVSAEQQRSIQTSLQELSGAPSACFLSCHSRDGLEELLTLLHNTLKTLCGDPLIGSPTLTQTRHRTHLQKSIEALQQYHEYRDVDLALAAEGLRLGLLSLGRITGRVSPEEILDVIFRDFCIGK
Protein: Class II, major histocompatibility complex, transactivator (A0A8I5ZK58)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTCLSFSLLPGHTLCATMELGSPEGSYLELLNSDADPLHLYHLYDQMDLAGEEEIELNSETDMDTINCDQFSKLLQDMEMDEETREAYANIAELDQYVFQDTQLEGLSKDLFIQHIGPEEGFGENVEGPAESGEKPQKRREKMGAVGNSTSLPLSPSVPPSRTSLNYLDLPAGHIQIFTTLPQGLWQISGVGTGLSSVLVYHGEMPQVNQLLSSSSPTVPSLPESPDRPGSTSPFAPSTADLPGMPEPALTSRVNETEDTTPPSPCQEDPEPSIKLPKWPESVERFQHSLQDKYQALPGSPSGPLVAMELVRARLERGSNKSQERELATPDWTERQLAHGGLAEVLRVVGDSRRSRETQVVAVLGKAGQGKSHWARTVSHIWAQGQLPQYDFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMDDEVIDHIVRQPDRVLLILDAFEELEAQDSLLHGPCGPLSPEPCSLRGLLAGLFQRKLLRGCTLLLTARPRGRLAQSLSKADAIFEVPSFSTKQAQIYMRHYFENSGTAGSHDKALGLLEGQPFLLTHSHSPVLCSAVCQLSKALLDQGAEAQLPCTLTGLYVGLLGPAAQNSPPGALVELAKLAWELGRRHQSTLQETQFPSVEVKTWAVAQGLMQQTTEAQLAFSSFLLQCFLGAVWLAQCNEMKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLVFQPRAHCLGALVEPAMAAVADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQEPGIWKHVSHQLPGHLSFLGTRLTAPDVYVLGRALETASQDFSLDLRQTGIEPSRLGDLVGLSCVTSFRASLSDTMALWESLQHQGETQLLQAAEEKFTIEPFKAKSPKDVEDLDSLVQTQRLRNPSADAAKDLPAIRDLKKLEFALGPVLGPQAFPTLAKILPAFSSLQHLDLDSLSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETLAMWTPTIPFGVQEHLQQLDARISLR
Protein: Olfactory receptor MOR258-2 (Olfr1339) (Olfactory receptor family 13 subfamily P member 5) (Q8VGB1)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Receptor-transporting protein 2
Sequence:
MQGSSYENHSSVSEFILLGFSSNFQLNIILFNVFFFLYLSTLVGNGLIVTLIHLDSRLHTPMYFFLSVLSMLDMSYVTTTVPQMLVHLLCQKKTISYSGCVAQMYIFLVLGITEGWLFSVMAYDRYVAICHPLRYKVIMRPWLCGAMVVFCGLWGVSCSLIYTVFTMRLPYCGPNEINHFFCEVPAVLKLACADTSLNDRIDFILGFILLLVPLSFILASYVCIFATILRIRSAQGRLKAFSTCASHITVVTMFCGPAMFMYMNPGANASPERDKKLALFYNVISAFLNPIIYSLRNKDVKRAFLKVTGWGGATE
Protein: Arabinose-proton symporter (Arabinose transporter) (P0AE24)
Organism: Escherichia coli (strain K12)
Function: Uptake of L-arabinose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system). D-fucose, a nonmetabolizable analog of L-arabinose, is also a good substrate.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:2836407, ECO:0000269|PubMed:7030324}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Ribulokinase
- L-arabinose isomerase
- L-ribulose-5-phosphate 4-epimerase AraD
- Broad specificity amino-acid racemase YgeA
- Arabinose operon regulatory protein
- Putative transporter AraJ
- L-arabinose-binding periplasmic protein
- Xylose isomerase
- Xylulose kinase
- Lactose permease
Sequence:
MVTINTESALTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIAGALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLGSIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLGIVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVLRMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNIIMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVMALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKCRDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETKNVTLEHIERKLMAGEKLRNIGV
Protein: GRAM domain-containing protein (Q18966)
Organism: Caenorhabditis elegans
Interaction partners:
- Cytochrome c domain-containing protein
- Cytochrome b-c1 complex subunit 7
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome b-c1 complex subunit 8
- Cytochrome b-c1 complex subunit 8
- Acyl-coenzyme A oxidase
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Mitochondrial-processing peptidase subunit beta
- Acyl-coenzyme A oxidase acox-1.1
- Cytochrome oxidase c subunit VIb
Sequence:
MSINTANTPDGLGVLLYNGETIVIFAQGVVMTLGTSENENLEGRRTGTIYLTSHRIIFMPDPGDWLKSFEIPFNSMQDVNLNQPIFGANYLCGIASAVQGGQMRGEVKWRMTFNRGGCIEFGQSLLQAVERAVRMRPENAPPAYSPPIGDFYSAPPAYYQPSPDQGPNGFNPTTDSFPDQPNPSRVFMSSAPPPYPGIGPERGPHPTEELHVAGQFEAPPAYGSGETADGLRRRN
Protein: Immunoglobulin-like domain-containing receptor 2 (Angulin-3) (Lisch-like protein) (B5TVM2)
Organism: Mus musculus (Mouse)
Function: May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23826244}; Single-pass type I membrane protein {ECO:0000269|PubMed:23826244}. Cell junction, tight junction {ECO:0000269|PubMed:23239027}. Nucleus {ECO:0000269|PubMed:28785060}.
Interaction partners:
- MARVEL domain-containing protein 2
Sequence:
MPAFPTLDLDGKLGKMDRVVLGWTAVFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKSYCQDRMGESLGMSSPRAQALSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIMPEWVFVGLVILGIFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHDDDSNFRQSYHQMRNKQFPMSGDLESNPDYWSGVMGGNSGTNRGPALEYNKEDRESFRHSQQRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRSRRANGNSHEARAGSRFERSESRAHGAFYQDGSLDEYYGRGRSREPPGDGERGWTYSPAPARRRPPEDAPLPRLVSRTPGTAPKYDHSYLSSVLERQARPESSSRGGSLETPSKLGAQLGPRSASYYAWSPPTTYKAGASEGEDEDDAADEDALPPYSELELSRGELSRGPSYRGRDLSFHSNSEKRRKKEPAKKPGDFPTRMSLVV
Protein: Somatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SSR-28) (P30936)
Organism: Rattus norvegicus (Rat)
Function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11134004, ECO:0000269|PubMed:9295322}; Multi-pass membrane protein {ECO:0000269|PubMed:11134004, ECO:0000269|PubMed:9295322}. Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation.
Interaction partners:
- Somatostatin
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- BBSome complex member BBS1
- Bardet-Biedl syndrome 9
- BBSome complex member BBS2
- BBSome complex member BBS4
- Bardet-Biedl syndrome 7 protein homolog
- Bardet-Biedl syndrome 5 protein homolog
Sequence:
MAAVTYPSSVPTTLDPGNASSAWPLDTSLGNASAGTSLAGLAVSGILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARMVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRVRSQEPGSGPPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQPGPSGQQQRPCTGTAKEQQLLPQEATAGDKASTLSHL
Protein: Uncharacterized protein (Q383B7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- AMP-dependent synthetase/ligase domain-containing protein
- Large ribosomal subunit protein uL4m
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MLRGTRGFLAVSPGVGIAPETTPVKYTPMMLNIQNMMWWNGKRNLYRATYREKTWYEISRTGAFTKGRRPVMRQKYSREALQAALAMVPPGFEVADVPRPPQRILAQSEGIVGRWYSNYWTLHSMRYQCLLAGVEWPLGERQRPRTNYDEPFFFADFEESKAIQDYRSRWINVNRSLVGMTKRMKEAEEEARYMQFRKLQDTFWSNRKVLVNRVKSMYNQGARTSAKDMPIKTINIKAFLSE
Protein: G patch domain-containing protein 3 (Q96I76)
Organism: Homo sapiens (Human)
Function: Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6.
Subcellular location: Nucleus {ECO:0000269|PubMed:28397860}. Cytoplasm {ECO:0000269|PubMed:28397860}.
Interaction partners:
- Zinc finger protein 408
Sequence:
MAVPGEAEEEATVYLVVSGIPSVLRSAHLRSYFSQFREERGGGFLCFHYRHRPERAPPQAAPNSALIPTDPAAEGQLLSQTSATDVRPLSTRDSTPIQTRTCCCVISVRGLAQAQRLIRMYSGRRWLDSHGTWLPGRCLIRRLRLPTEASGLGSFPFKTRKELQSWKAENEAFTLADLKQLPELNPPVLMPRGNVGTPLRVFLELIRACRLPPRIITQLQLQFPKTGSSRRYGNVPFEYEDSETVEQEELVYTAEGEEIPQGTYLADIPASPCGEPEEEVGKEEEEESHSDEDDDRGEEWERHEALHEDVTGQERTTEQLFEEEIELKWEKGGSGLVFYTDAQFWQEEEGDFDEQTADDWDVDMSVYYDRDGGDKDARDSVQMRLEQRLRDGQEDGSVIERQVGTFERHTKGIGRKVMERQGWAEGQGLGCRCSGVPEALDSDGQHPRCKRGLGYHGEKLQPFGQLKRPRRNGLGLISTIYDEPLPQDQTESLLRRQPPTSMKFRTDMAFVRGSSCASDSPSLPD
Protein: WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog) (Q9P2L0)
Organism: Homo sapiens (Human)
Function: As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. May promote CASP3 activation and TNF-stimulated apoptosis.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8BND3}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q8BND3}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q8BND3}.
Interaction partners:
- Tetratricopeptide repeat protein 21B
- Intraflagellar transport protein 43 homolog
- WD repeat-containing protein 19
- Intraflagellar transport protein 122 homolog
- Intraflagellar transport protein 140 homolog
- Engulfment and cell motility protein 3
- Dedicator of cytokinesis protein 1
- Engulfment and cell motility protein 1
- Engulfment and cell motility protein 2
- Intraflagellar transport protein 80 homolog
Sequence:
MFFYLSKKISIPNNVKLQCVSWNKEQGFIACGGEDGLLKVLKLETQTDDAKLRGLAAPSNLSMNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLIIVWMLYKGSWIEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLSHVTWSADSKVLLFGMANGEIHIYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYHGTEGYVEPDCPCLAVCFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHMGSVLAVAGFQKAAMQDKDVNIVQFYTPFGEHLGTLKVPGKEISALSWEGGGLKIALAVDSFIYFANIRPNYKWGYCSNTVVYAYTRPDRPEYCVVFWDTKNNEKYVKYVKGLISITTCGDFCILATKADENHPQEENEMETFGATFVLVLCNSIGTPLDPKYIDIVPLFVAMTKTHVIAASKEAFYTWQYRVAKKLTALEINQITRSRKEGRERIYHVDDTPSGSMDGVLDYSKTIQGTRDPICAITASDKILIVGRESGTIQRYSLPNVGLIQKYSLNCRAYQLSLNCNSSRLAIIDISGVLTFFDLDARVTDSTGQQVVGELLKLERRDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYICNFEDLEIKSVLLDEILKDPEHPNKDYLINFEIRSLRDSRALIEKVGIKDASQFIEDNPHPRLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFVKRLGKLLSESMKQAEVVGYFGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGDADDSLLEQANNAIGDYFADRQKWLNAVQYYVQGRNQERLAECYYMLEDYEGLENLAISLPENHKLLPEIAQMFVRVGMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHLLEKNKTLDAIELYRKANYFFDAAKLMFKIADEEAKKGSKPLRVKKLYVLSALLIEQYHEQMKNAQRGKVKGKSSEATSALAGLLEEEVLSTTDRFTDNAWRGAEAYHFFILAQRQLYEGCVDTALKTALHLKDYEDIIPPVEIYSLLALCACASRAFGTCSKAFIKLKSLETLSSEQKQQYEDLALEIFTKHTSKDNRKPELDSLMEGGEGKLPTCVATGSPITEYQFWMCSVCKHGVLAQEISHYSFCPLCHSPVG
Protein: Double-strand break repair protein MRE11 (AtMre11) (Q9XGM2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P49959}. Chromosome {ECO:0000250|UniProtKB:P49959}. Note=Localizes to DNA double-strand breaks (DSBs). {ECO:0000250|UniProtKB:P49959}.
Interaction partners:
- DNA repair protein RAD50
- Nibrin homolog
- Serine/threonine-protein kinase ATR
- Serine/threonine-protein kinase ATM
- ATP-dependent DNA helicase 2 subunit KU70
- ATP-dependent DNA helicase 2 subunit KU80
- DNA ligase 6
- Exonuclease 1
- Dentin sialophosphoprotein-like protein
- DNA repair protein RAD51 homolog 1
Sequence:
MSREDFSDTLRVLVATDCHLGYMEKDEIRRHDSFKAFEEICSIAEEKQVDFLLLGGDLFHENKPSRTTLVKAIEILRRHCLNDKPVQFQVVSDQTVNFQNAFGQVNYEDPHFNVGLPVFSIHGNHDDPAGVDNLSAIDILSACNLVNYFGKMVLGGSGVGQITLYPILMKKGSTTVALYGLGNIRDERLNRMFQTPHAVQWMRPEVQEGCDVSDWFNILVLHQNRVKSNPKNAISEHFLPRFLDFIVWGHEHECLIDPQEVSGMGFHITQPGSSVATSLIDGESKPKHVLLLEIKGNQYRPTKIPLTSVRPFEYTEIVLKDESDIDPNDQNSILEHLDKVVRNLIEKASKKAVNRSEIKLPLVRIKVDYSGFMTINPQRFGQKYVGKVANPQDILIFSKASKKGRSEANIDDSERLRPEELNQQNIEALVAESNLKMEILPVNDLDVALHNFVNKDDKLAFYSCVQYNLQETRGKLAKDSDAKKFEEDDLILKVGECLEERLKDRSTRPTGSSQFLSTGLTSENLTKGSSGIANASFSDDEDTTQMSGLAPPTRGRRGSSTANTTRGRAKAPTRGRGRGKASSAMKQTTLDSSLGFRQSQRSASAAASAAFKSASTIGEDDVDSPSSEEVEPEDFNKPDSSSEDDESTKGKGRKRPATTKRGRGRGSGTSKRGRKNESSSSLNRLLSSKDDDEDEDDEDREKKLNKSQPRVTRNYGALRR
Protein: Protein kinase, putative (Q38C94)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Atg6 BARA domain-containing protein
- phosphatidylinositol 3-kinase
- Protein kinase, putative
- Autophagy-related protein 9
- Autophagocytosis associated protein, putative
- Autophagy-related protein 2
- Autophagy-related protein
- Autophagy-related protein
- Autophagy-related protein
- Cysteine protease
Sequence:
MRSCCSCGKAWCCPERVEDRAEEILKGYVDCFGIDDYRNVQRMAELSGLLSHCSQVDWSNVAGSVSIGLIFRGKHVEDDCDVVVSVLKRPANKKDELSRYVQKEVGVLAINFPNIIRVVDYFSVIEGEWAYSMALLKWLGGDGIVEFFTQSVLGKGRASDVERDDIELRRHPTVDATRIMQGNVEGDYFDSKWRPSTPVREGNTCVVGDYEMYMDESLGKGQFGEVYRGKHIKEGYHVAMKIIKAPAKKRDETPDEISIMDLLGCPGHPNVVKAYGTYETIDDKNEPSYVLVLELCEGGDLKEYLAKHDPLSEAQARRIMRQLVDCLCFLRERGVMHRDLKPANILLTSCNIDEAVVKVADWGMAKVNSRKGSALEATEGEEMFESAVGTMAYMAPERLNFDSYDYQAEVWALGVIMYELLFARHPYIYPKATVCSADALLGAIARAEQLDMTNRAPSASTSTTDGAGGELSQQEGGYVNRRRLSPSCYELLRQMLHSEAKKRCTIIDVKNHVWFTHEEPRSAPVLVRGGSPRSVLADALGSASGVTLAGQALAEYPSAVDNSVLPVENCEGGRNVLTTLEKRQTILALREYIHILQYNIVERERDPGRGLVLLSYGWDLLSAAVNTVFSECSNVAGDTGGAANATNGPNMSASSSLFHDSLDDLKQVEGYIQTAASQLKQSLQSNQGTQTTASSAADNEEGVTQHSFTLMTRGTSLDCLPSAKELMLRHAVDLIRWAASEQLLLTPDDKREKQRGVLEAELEPKKLQGKKLWEDAMAILRLLLQQVVVYSPTVTTRSIIADATMGGSVQVLNVPLVPLTHEEDRRTVQALLHKVEGLYRNLFVRV
Protein: Solute carrier family 22 (Organic cation/carnitine transporter), member 5 (Solute carrier family 22 member 5) (Q2KJE9)
Organism: Bos taurus (Bovine)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004424}. Basal cell membrane {ECO:0000256|ARBA:ARBA00034696}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034696}. Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}.
Interaction partners:
- Solute carrier family 22 member 2
- Solute carrier family 22 member 1
- Solute carrier family 22 member 3
- High affinity choline transporter 1
- Choline transporter-like protein 4
- Choline transporter-like protein
- Choline transporter-like protein 2
- Solute carrier family 22 member 4
- Choline transporter-like protein 3
- Leucine rich repeat containing 9
Sequence:
MQDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGLSSVFFTATPEHHCRVPDTANLSSAWRNHSVPMRLQDGREVPQSCRRYRLAMMVNFSELGLEPGRDVDLEQLEQEGCLDGWEFSQDIYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLMGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFTVLFFLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMLLPLFAYFIRDWRMLLLALTVPGVLCAALWWFIPESPRWLISQGRFQEAEVIIRRAAKTNGIIAPSTIFDSSELQDLSSKKQQSHSILDLIRTRNIRMITVMSIILWLTISVGYFGLSLDTPNLHGDVYLNCFLSAVVEVPAYVLAWLLLRHLPRRYSMATALFLGGSVLLFVQLVPPELYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPETFGTPLPDTIDQMLRVKGIKYRQTPSHTRMLKDGEESPTVLKSTSF
Protein: Ladderlectin (P81018)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Lectin that binds sepharose in a calcium-dependent manner.
Interaction partners:
Sequence:
MAMLTISLLLCAAVALNGATVLELFQDFEQALHLGAKGEDERVVAAENRNQCPTGWFQFGSRCFMFVETARSWPLAERHCVSLGANLASVHSSAEYQFLQEVVASKTGGFSTPWIGGFDAVQDRLWFWSDGSEFDYQNWKKGEPNNSGGREPCIVINWRDEYRWNDINCGNSFPSGVLQKNVEIQKNEPT
Protein: Stretchin-MLCK (Q9NBB7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
YTLFARTKWQDVVRRHVELIVEDRSTGDDPPVFVRRLPDLSVKVGTRTRLLTEIRSSTDLKLTWYRNDRRVCANDRITEVNEGTFHYLEISPVTLDDGGQWMLMAENFGGRNSCLGTLNVLVPKAYKTPEFVEELRAVLTEQGTVSLECKV
Protein: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (E7F0G2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000256|ARBA:ARBA00037848}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00037848}.
Interaction partners:
- heparosan-N-sulfate-glucuronate 5-epimerase
- D-glucuronyl C5-epimerase B
- [heparan sulfate]-glucosamine N-sulfotransferase
- [heparan sulfate]-glucosamine N-sulfotransferase
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
- Heparan-sulfate 6-O-sulfotransferase 1-B
Sequence:
MLCVFRLRRLVRQVPLHTSFLFLFLLCVLSVFLSSYFLYAVKRELEPSAIGGHAAAGDLYVTPSRTLSFMGGTFSSDGSRTDPVVLVFVESQYSHLGQEIVAILESARFRYRTEISPGKGDMPTLMEGRRGRFILIVYENILKYVNMDAWNRELLDRYCIEFGVGIIGFFKANENSLSSAQLKGFPLFLRSNLGLKDCSINPKSPLLHITRAQQVSGPLPGDDWTVFQSNHSSYEPVVLAKALSADSPLHTTVLQDLGLHDGIQRVLFGHNLSFWIHKLVFVDAVSFLTAKRLSLSLERFILVDIDDIFVGKEGTRMKVADVEALLETQNELRRSIPGFTFNLGFSGKFFHAGTDEEDQGDDLLLSYVDEFWWFPHMWSHMQPHRFHNQSVLAEQMILNRRFAEDHSIPTHLGYAVAPHHSGVYPVHIQLYEAWKRVWDIRVTSTEEYPHLKPARFRRGFIHRGIRVLPRQTCGLFTHTIFHEEYPGGPQELEHLIHGGELFLTVLLNPISIFMTHMSNYGNDRLGLFTFKRLLDFLQTWTHLKLQTLPPLQLAEKYFHMFPSDTEPLWQDPCEDKRHKDIWSKEKTCDRFPKLLLIGPQKTGTTALYLFLGMHPDLTSNYPSKETFEEIQFFSGYNYQRGIDWYMEYFPLPSNSSSEYYFEKSANYFDSDVAALRAAALLPRAKIITVLSDPVDRAYAWYQHQRVHGDPVALKYSFHDVITASHNAPVRLQTLQKRCLLPGFYSKHLTRWIQHFHHSQILVVDGQTLKTDPASVLEKIQTFLGLENRVDYHKILAFNPKKGFWCQLLDGGKTKCLGRSKGQRYPDMDTQSQVFLRNYYSDGNIELSKLLYKMGQTVPGWLRQELLHTR
Protein: PBS1-like 1 (F4IWV6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
Sequence:
MGSCLSSRVLSTFSTILHLPFFFFFFFFPFFGVLSILTVVNAFVCCADKSSSGLDDLHLSSCKSSSSATAHKTEGEILSSTTVKSFSFNELKLATRNFRSDSVVGEGGFGCVFRGWLDETTLTPTKSSSGLVIAVKRLNPDGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEQRLLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGLAFLHSDPVKVIYRDIKASNILLDSDFNAKLSDFGLARDGPMGEQSYVSTRVMGTFGYAAPEYVSTGHLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLIVDTRLNSQYKPEGAVRLASIAVQCLSFEPKSRPTMDQVVRALVQLQDSVVKPANVDPLKVKDTKKLVGLKTEDKYQRNGLNKKTVGL
Protein: PDZ domain-containing protein (Q38AT6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAGAEQRQFHSVEEVSVELGRASLHASWGFKTYDGVCPLRVRDVAAEIPEGVRRGDEIIVINGIRPGSYDEGMSLLHQAQSTVQLCVRRKVSGSKCATTVDEGAEPRECEYIGIERNSWRNRASLHSLSPSAEWEGTISPQQQQRKPADQTTATSCHHSESGVRTSAQLALDKVLLAACGKDAHCEDTITEGTTDTEGPPSGPSRAPLSINSQVAGIWRGILTRKRKRLDDASRDSKNYMDVCSVLPKLTHQVIYDCQNCPFSIEEGFVPEFHKSVQYIMTERALSQKHAAGDEDGDGDAKVMLAPVKDRSDEDLSAVMAQVEAKKAQCEKEVSQRDTVADVHRMKKMLSSQQSGMLKVVESHRESLLQKLREDVGWYRETECSAQDFFALHSKAISWCRKASIKQSPVDSKVKYPAFHHGNREGHKRHEHPQLLPPPPPPPPPPLSQPHFPPPPFAAAPSSAAVVPVSTVSPRGRVGYVAPPGYARRLPQHPPLFDVRTLNATLYHR