wanglab/gogpt-training-data huggingface dataset:
Protein: Metal resistance protein YCF1 (ABC-type Cd(2+) transporter) (EC 7.2.2.2) (ABC-type glutathione-S-conjugate transporter) (EC 7.6.2.3) (Yeast cadmium factor 1) (P39109)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cooperates for the ATP-dependent vacuolar transport of bilirubin and glutathione conjugates.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:8626454}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:8626454}.
Interaction partners:
- Arsenical-resistance protein 3
- Bile pigment transporter 1
- Oligomycin resistance ATP-dependent permease YOR1
- Glutathione reductase
- Protein SNQ2
- Arsenical-resistance protein 2
- ATP-dependent permease PDR10
- AP-1-like transcription factor YAP1
- ATP-dependent permease PDR11
- Arsenical-resistance protein ARR1
Sequence:
MAGNLVSWACKLCRSPEGFGPISFYGDFTQCFIDGVILNLSAIFMITFGIRDLVNLCKKKHSGIKYRRNWIIVSRMALVLLEIAFVSLASLNISKEEAENFTIVSQYASTMLSLFVALALHWIEYDRSVVANTVLLFYWLFETFGNFAKLINILIRHTYEGIWYSGQTGFILTLFQVITCASILLLEALPKKPLMPHQHIHQTLTRRKPNPYDSANIFSRITFSWMSGLMKTGYEKYLVEADLYKLPRNFSSEELSQKLEKNWENELKQKSNPSLSWAICRTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFENNHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVLSNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNNKELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVFVYTEDRALTTDLVFPALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDVAINIGDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLGDLFRVKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGPNGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEITKDADSPLWKLLNNYGKKNNGKSNEFGDSSESSVRESSIPVEGELEQLQKLNDLDFGNSDAISLRRASDATLGSIDFGDDENIAKREHREQGKVKWNIYLEYAKACNPKSVCVFILFIVISMFLSVMGNVWLKHWSEVNSRYGSNPNAARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMTNSVLRAPMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYSQQKRFSHINQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTLTAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEAPLIVEGHRPPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAIWRALELSHLKEHVLSMSNDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDNKSLFYSLCMEAGLVNEN
Protein: Gamma-tubulin complex component 2 (AtGCP2) (GCP-2) (Protein SPIRAL 3) (Spindle pole body protein Spc97 homolog) (AtSpc97) (Q9C5H9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Gamma-tubulin complex is necessary for microtubule nucleation at the microtubule organizing centers (MTOCs). Required for the positioning of the gamma-tubulin-containing complex on pre-existing microtubules and for the proper organization of cortical arrays.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q9BSJ2}. Nucleus envelope. Cytoplasm. Cytoplasm, cell cortex. Note=Associated to motile complexes in the cytosol that transiently stabilized at fixed locations in the cell cortex (e.g. along the outer periclinal edge of newly formed crosswalls) from which microtubules grow away prior to microtubules nucleation. Colocalizes with gamma-tubulin at the nuclear surface where microtubules are nucleated.
Interaction partners:
- Tubulin gamma-2 chain
- Gamma-tubulin complex component 3
- Gamma-tubulin complex component 4
- Tubulin gamma-1 chain
- Spindle pole body component
- Spc97 / Spc98 family of spindle pole body
- Gamma-tubulin complex component
- Gamma-tubulin complex component
- Mitotic-spindle organizing protein 1B
- At1g80245 component)
Sequence:
MESMTPISCPTTPRWNQDRPFLTGRFHQETRASSKFADSKRFTLDSSSSGVEQAIGCYDTPVQELIVIDDLLSALVGIEGRYISIKRFHGKEDSIAFQVDPSMDLALQELAKRIFPLCEYYLLIDQFVESSSQFKNGLVNHAFAAALRALLLDYQAMVAQLEHQFRLGRLSIQGLWFYCQPMMGSMRALAAVIQQASTKQFVGSGVLNLLQSQAKAMAGDNSVRSLLEKMTECASNAYLSILERWVYEGIIDDPYGEFFIAENRSLKKESLSQDSTAKYWSQRYSLKDTIPGFLANIAATILTTGKYLNVMRECGHNVQVPISERSKLTIFGSNHHYLECIKAAHEFASIELVNLIKDKYDLVGRLRSIKHYLLLDQGDFLVHFMDIAREELNKKVHEISVEKLQSLLDLALRTTAAAADPRHEDLTCCVDRASLLTTLGMHKDTDSNSIEDPMSITGLETFSLSYKVQWPLSIVISKKALSKYQLIFRFLFHCKHVERQLCGAWQIHQGIRSMNSKGTAILRSSLLCRSMLKFISSLLHYLTFEVLEPNWHVMHDRLQSTRSVDEVIQHHDFFLDKCLRGCLLLLPDVLKKMEKLKSVCLQYAAATQWLISSSIDINSQSHPQKTMIRDTTVTESIFNFEREFNSELQSLGPVLSKGSQAEPYLTHLSQWILGVSKE
Protein: Monodehydroascorbate reductase, chloroplastic/mitochondrial (EC 1.6.5.4) (Monodehydroascorbate reductase 5, mitochondrial) (AtMDAR5) (Monodehydroascorbate reductase 6, chloroplastic) (AtMDAR6) (P92947)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the conversion of monodehydroascorbate (MDA) to ascorbate, oxidizing NADH in the process. Can also use 2,4,6-trinitrotoluene (TNT) and 1-chloro-2,4-dinitrobenzene (CDNB) as substrates, but not 1-chloro-4-nitrobenzene (CNB).
Subcellular location: [Isoform MDAR6]: Plastid, chloroplast {ECO:0000269|PubMed:12154132}.; SUBCELLULAR LOCATION: [Isoform MDAR5]: Mitochondrion {ECO:0000269|PubMed:12154132, ECO:0000305|PubMed:25732537}.
Interaction partners:
- L-galactono-1,4-lactone dehydrogenase, mitochondrial
- Glutathione S-transferase DHAR2
- Glutathione S-transferase DHAR1, mitochondrial
- Glutathione S-transferase DHAR3, chloroplastic
- L-ascorbate peroxidase S, chloroplastic/mitochondrial
- Rieske
- L-ascorbate peroxidase T, chloroplastic
- L-ascorbate peroxidase 1, cytosolic
- F18O14.31
- L-ascorbate peroxidase 2, cytosolic
Sequence:
MSAVRRVMALASTTLPTKSGLSLWCPSSPSLARRFPARFSPIGSRIASRSLVTASFANENREFVIVGGGNAAGYAARTFVENGMADGRLCIVTKEAYAPYERPALTKAYLFPPEKKPARLPGFHTCVGGGGERQTPDWYKEKGIEVIYEDPVAGADFEKQTLTTDAGKQLKYGSLIIATGCTASRFPDKIGGHLPGVHYIREVADADSLIASLGKAKKIVIVGGGYIGMEVAAAAVAWNLDTTIVFPEDQLLQRLFTPSLAQKYEELYRQNGVKFVKGASINNLEAGSDGRVSAVKLADGSTIEADTVVIGIGAKPAIGPFETLAMNKSIGGIQVDGLFRTSTPGIFAIGDVAAFPLKIYDRMTRVEHVDHARRSAQHCVKSLLTAHTDTYDYLPYFYSRVFEYEGSPRKVWWQFFGDNVGETVEVGNFDPKIATFWIESGRLKGVLVESGSPEEFQLLPKLARSQPLVDKAKLASASSVEEALEIAQAALQS
Protein: Voltage-dependent T-type calcium channel subunit alpha (Q7Z002)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}.
Interaction partners:
Sequence:
MLRQPVPELRSFQSLSKYAGGPRSVLGRRTSAITVNRRQSQSTRRHEDVEALGSIEGSKETLQLSEHGRLASSSEASPSRWEGRQIEWGNEEQIEEESELPYPGFAEPALRCFYQARPPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVINLPKTISENQSALFNNVKLTRFYIPEDTSLEYICSQPDANGLHTCSNLPPYTVDGVKCNLTLDEYDKVTNDSCINWNIYYNECQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRETERMLQERKMLLNRDSISCTGSEIGGASSKEEGDTVYAAFVRFIGHTFRRTKRAAKKKYTAYMEERAERKSSERQQRRKSKLDDMATLSRIEEKAEDEEDETTITRENGDDQIEQNGDGVRIKRVKIEEEPKIKIGNGNSNGPHYKHSSSDEESDEDGEEDQVYDGEEAKKKSTPSKLWWFREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQEGKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKKCERKNFDTLLWALITVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARKQAVEEEDERKRELELIIAKTTSPAFNNGVAPAECTCQRPSSPEESPSPRLLSANYHPSPERKHSANLDAIIDKRLVLRNSAPFDRSPVSEGRDDSRLNRHASLVLPVANGVPYRRQRVHSWSGLCHHFNPNCPVHGRRALIETYAREKFLEASQELKQALAEEEKRNEAKQNTFVRKLLKKTCLHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKEKEKRLKRKLKRQKFEESMAGKRKKNRIVWAGSAIKSIFSVERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDALRDDCDSSDHCETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKHLEESNKRDAEGPAEPTGENIENEITKSDDDEIVEEHEPLAIEHVKEGELDEEEETEEGPTTQIPDGHGGIKRLSMQVLEQELIEVERHLEERYRRASECLGGELQPLNPGEIEDLDDPEFRPRSRSHRPRARTNSALSNKSRGSHKSAL
Protein: Long-chain-fatty-acid--luciferin-component ligase (EC 6.2.1.19) (Acyl-protein synthetase) (P24272)
Organism: Aliivibrio fischeri (Vibrio fischeri)
Function: Acyl-protein synthetase activates tetradecanoic acid. It is a component of the fatty acid reductase complex responsible for converting tetradecanoic acid to the aldehyde which serves as substrate in the luciferase-catalyzed reaction.
Interaction partners:
Sequence:
MTVHTEYKRNQIIASSEIDDLIFMTKPQEWSFEEQKEIRDKLVREAFYFHYNRNEEYRNYCINQHVSDNLHTIDEIPVFPTSVFKYKKLHTVTAEDIENWYTSSGTRGVKSHIARDRLSIERLLGSVNFGMKYVGDWFEHQMELINLGPDRFNTNNIWFKYVMSLVELLYPTEFTVDNDKIDFEKTVKHLFRIKNSKKDICLIGPPFFVYLLCQYMKENNIEFKGGDRVHIITGGGWKSNQNDSLDRADFNQLLMDTFQLDKINQIRDTFNQVELNTCFFEDEFQRKHVPPWVYARALDPETLKPVADGEIGLLSYMDASSTAYPAFIVTDDIGIVKEIREPDPYPGVTVEIVRRLNTRAQKGCALSMANVIQKNIKD
Protein: Resistin-like beta (Colon and small intestine-specific cysteine-rich protein) (Colon carcinoma-related gene protein) (Cysteine-rich secreted protein A12-alpha-like 1) (Cysteine-rich secreted protein FIZZ2) (RELMbeta) (Q9BQ08)
Organism: Homo sapiens (Human)
Function: Probable hormone.
Subcellular location: Secreted.
Interaction partners:
- Toll-like receptor 4
- Adenylyl cyclase-associated protein 1
- Adiponectin
- Leptin
- Nicotinamide phosphoribosyltransferase
- Decorin
- Insulin
- Arginase-1
- Interleukin-6
- Intelectin-1
Sequence:
MGPSSCLLLILIPLLQLINPGSTQCSLDSVMDKKIKDVLNSLEYSPSPISKKLSCASVKSQGRPSSCPAGMAVTGCACGYGCGSWDVQLETTCHCQCSVVDWTTARCCHLT
Protein: Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specific factor 1) (A0A0R4IC37)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). Plays a role in eye morphogenesis and the development of retinal ganglion cell projections to the tectum.
Subcellular location: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q10570}.
Interaction partners:
- Cleavage and polyadenylation specificity factor subunit 2
- Symplekin
- Cleavage and polyadenylation-specific factor 3.
- Pre-mRNA 3' end processing protein WDR33 isoform 2
- Cleavage and polyadenylation-specific factor 4.
- WD repeat-containing protein 82
- Pre-mRNA 3'-end-processing factor FIP1
- PCF11 cleavage and polyadenylation factor subunit.
- Cleavage stimulation factor subunit 3
- Cleavage stimulation factor, 3' pre-RNA, subunit 2.
Sequence:
MYAVYRQAHPPTAVEFAVYCNFISSQEKNLVVAGTSQLYVYRIIYDVESTSKSEKSSDGKSRKEKLEQVASFSLFGNVMSMASVQLVGTNRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHYFEEPELRDGFVQNVHIPMVRVDPENRCAVMLVYGTCLVVLPFRKDTLADEQEGIVGEGQKSSFLPSYIIDVRELDEKLLNIIDMKFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSIVAISLNIMQKVHPVIWSLSNLPFDCNQVMAVPKPIGGVVVFAVNSLLYLNQSVPPFGVSLNSLTNGTTAFPLRPQEEVKITLDCSQASFITSDKMVISLKGGEIYVLTLITDGMRSVRAFHFDKAAASVLTTCMMTMEPGYLFLGSRLGNSLLLRYTEKLQETPMEEGKENEEKEKQEEPPNKKKRVDSNWAGCPGKGNLPDELDEIEVYGSEAQSGTQLATYSFEVCDSILNIGPCASASMGEPAFLSEEFQTNPEPDLEVVVCSGYGKNGALSVLQKSIRPQVVTTFELPGCHDMWTVIYCEEKPEKPSAEGDGESPEEEKREPTIEDDKKKHGFLILSREDSTMILQTGQEIMELDTSGFATQGPTVYAGNIGDNKYIIQVSPMGIRLLEGVNQLHFIPVDLGSPIVHCSVADPYVVIMTAEGVVTMFVLKNDSYMGKSHRLALQKPQIHTQSRVITLCAYRDVSGMFTTENKVSFLAKEEIAIRTNSETETIIQDISNTVDDEEEMLYGESNPLTSPNKEESSRGSAAASSAHTGKESGSGRQEPSHWCLLVRENGVMEIYQLPDWRLVFLVKNFPVGQRVLVDSSASQSATQGELKKEEVTRQGDIPLVKEVALVSLGYNHSRPYLLAHVEQELLIYEAFPYDQQQAQSNLKVRFKKMPHNINYREKKVKVRKDKKPEGQGEDTLGVKGRVARFRYFQDISGYSGVFICGPSPHWMLVTSRGAMRLHPMTIDGAIESFSPFHNINCPKGFLYFNKQGELRISVLPTYLSYDAPWPVRKIPLRCTVHYVSYHVESKVYAVCTSVKEPCTRIPRMTGEEKEFETIERDERYIHPQQDKFSIQLISPVSWEAIPNTRVDLEEWEHVTCMKTVALKSQETVSGLKGYVALGTCLMQGEEVTCRGRILILDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCSGFLVSAIGQKIFLWSLKDNDLTGMAFIDTQLYIHQMYSIKNFILAADVMKSISLLRYQPESKTLSLVSRDAKPLEVYSIEFMVDNNQLGFLVSDRDKNLMVYMYLPEAKESFGGMRLLRRADFNVGSHVNAFWRMPCRGTLDTANKKALTWDNKHITWFATLDGGVGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPKAFRMLHCDRRTLQNAVKNILDGELLNKYLYLSTMERSELAKKIGTTPDIILDDLLEIERVTAHF
Protein: Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2) (P28841)
Organism: Rattus norvegicus (Rat)
Function: Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells (By similarity).
Subcellular location: Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P16519}. Secreted {ECO:0000250|UniProtKB:P16519}. Note=Localized in the secretion granules. {ECO:0000250|UniProtKB:P16519}.
Interaction partners:
- Neuroendocrine protein 7B2
- Carboxypeptidase E
- Neurogenic differentiation factor 1
- Receptor-type tyrosine-protein phosphatase N2
Sequence:
MEGGCGSQWKAAGLLFCVMVFASAERPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNSDASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANVDLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKLVLTLQTNACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGLLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKQELEEELDEAVERSLQSILRKN
Protein: Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase DTK) (Q9YI66)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May be involved in cell adhesion processes, particularly in the central nervous system.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Growth arrest-specific 6.
- Protein S.
Sequence:
MEVSLCILLFLLHFNEGIHGVRFTQKPFHQTVTQGNMVRLGCAFEGLSEPEIIWMKDGEKLFSTDQMYITLDPYHWETFHSVKSVQQQDAGKYWCEVEYHGAIISSEPAWITVAGVPHFGVEPEDVAAFAGESFNLTCAASGPPEPVEVLWWLGGEQNGDFTPSPSVLFVKGVNESIKFHCEPRNARGISVSRTGTVHIKARPDSLGRTGHHVSDFNITLTWSPGFTGHSQLSTCTIQLSRGPGEVKLPDVVVEVPPFQHVFEGLRSYSNYSVRVRCDNEVGSSPFSPWVDFHTPQAAPSAAPKNFTFDLSEQQLTLSWATLEQEELRGRLQEELRGRLLAYKLQWNQGGESQDPLLFKENVAHLSGAGRFFNATFQVAACTMAGCGPWSQPVLVMPVSAMQAQTQRGHMWVGLLFGLLVATMVGLLLIVLIRNRGKETQFGSAFAAQGAEVPVSFTAARSFNRQFPELPESTLDSLGINSDLKAKLQDVLIFERLLTLGRMLGKGEFGSVREAFLKSENNSGQKVAVKVLKTDINSSSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHRRAQQRLPIPMVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKNIIHRDLAARNCMLNENMSVCVADFGLSKKIYSGDYYRQGSVSKLPVKWIALESLADNVYTTQSDVWAFGVTMWEIMTRGQTPYPGVENSEIYEYLIKGERLKQPPDCPADIYEIMHSCWSPVPKCRPSFQHLIDQLELLWAKLNPAPVKEPLLYVNLEEEDGEQANSGTRSSEEPSWGVPWQCAGIEEDEKDWLMVSSGAALAIGGDYRYIIGPSVSAIDEESRHSEDGLSEDIREEEEDVIINV
Protein: CC chemokine receptor 7 (L7UKG5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MTTEFITDFTDYPTDNTDLDYDHWTQQCQKESNRHFRSWFMPTFYSLICFLGLVGNILVIGTYVYFNRLKTGTDVFLLSLSVADLLFVVSLPLWATNSMTEWVLGLFICKAMHTIYKVSFYSGMFLLASISVDRYFAISKAVSAHRHRSMAVFISKVTSVVIWVMALVFSVPEMSYTNISNKTCTPYTAGSDQVRVAIQVSQMVFGFVLPLLIMAFCYGAIVKTLCQARSFEKNKAIKVIFTLVAVFLLCQVPYNLVLLLTTLDAAKGGSKDCLYDNSLLYAADITQCLSFLRCCLNPFVYAFIGVKFRRDLLKLLKDLGCMSKERFFQYTCGKRRSSAVAMETETTTTFSP
Protein: Uncharacterized protein (Q57VW0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRTFFSHVMGAWKSKRQLPRAEVDCSDLIKSFPQAPTTAELRQVVHRRLFGSVGPASSEAEALHREMGIRHTVFDLQYRCGASGRCCCCERIEPSDGPHMATSGGHVSDNSKMGPTSTTTSGTSDAASMLSMTIKGSSVCRFPRCFAMRPITKGAEVLAVRLAYEVDDAPTPKIRGLIKLAREERLAAAVHGIQQLVDAEIRLAAGGRVLSSAFQLQHQYSDASATSIGCHVGFNGGGGGDSGYYSYSAGGEACEVSPAALKYGSESAVGGGGVNPLLEEAALREEIVSLYLWRASLLVNMREDERAVSSLLNLAALLAPKSNTRTNHNSDDTKQQPNRDEGQKEEQFRQLQQDRLRLYTSAASWAALNDMEVIYYRSLLKRYEPFPLAETFAHDRPLLLKRVVEACRCDNGGSLNCPNGVNSGSCSYSSVADAETVAYITECIAHTVFAKEVTATVSRAQAAQQHGDLTEDPMRSLCLPFALRYYRFYVGGAFWEHFFRLLCMPPIPPSGRNEEAERLGLTPNYVLDAVGRSMLLHHLVMLHEVREREIADGTVASTIRELHKEQSLAAAASACEGNGDMGGCGDSGVPVHPAHYEHVLTDRERAVAVTRLRELLIVGRGYESVLSGKGANNNDTGSSGNSAGGNNGDGDGGSNNNKTSV
Protein: AP complex subunit sigma (F1Q5Z2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004180}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit {ECO:0000256|ARBA:ARBA00004600}.
Interaction partners:
Sequence:
MRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
Protein: Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein) (Q9D3A8)
Organism: Mus musculus (Mouse)
Function: Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity). In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.
Subcellular location: Cell projection, filopodium {ECO:0000250|UniProtKB:O54960}. Cell projection, podosome {ECO:0000250|UniProtKB:O54960}.
Interaction partners:
- Nitric oxide synthase 1
- Dexamethasone-induced Ras-related protein 1
- Predicted gene 7694
- Disks large homolog 4
- Alpha-1-syntrophin
Sequence:
MPSKTKYNLVDDGHDLRIPLHNEDAFQHGISFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVSTAAAEETDIDAVEVPLPGNDILEFSRGVTDLDAVGKDGGSHIDSTVSPHPQEPMLTASPRMLLPSSSSKPPGLGTGTPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNTMGSQDSLLEITFRSGALPVLCESTTPKPEDLHSPLLGAGLADFAHPAGSPLGRHDCLVKLECFRFLPPEDTQPMMAQGEPLLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDSLDDEIAV
Protein: Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase) (Q63448)
Organism: Rattus norvegicus (Rat)
Function: Oxidizes the CoA-esters of 2-methyl-branched fatty acids.
Subcellular location: Peroxisome {ECO:0000305|PubMed:8706733}.
Interaction partners:
- Trifunctional enzyme subunit beta, mitochondrial
- Peroxisomal bifunctional enzyme
- Peroxisomal multifunctional enzyme type 2
- Enoyl-CoA hydratase, mitochondrial
- 3-ketoacyl-CoA thiolase, mitochondrial
- Trifunctional enzyme subunit alpha, mitochondrial
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Long-chain specific acyl-CoA dehydrogenase, mitochondrial
- Acetyl-CoA acetyltransferase, cytosolic
- Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Sequence:
MGSSSERRDSVLWSDIPKGPLSAYRARASFNSKELMLFWDGQDVLDFKKTIFSTLENDPLFARPFGADLPLEKERELNFLRCKRVFEYGFFNAEDMLKNPLKILVLMNCLGMYDWSLANKCVLHMLVFGSTIIGSGSEHHFKYLEKIYNLEIFGCFALTELSHGSNTKAMRTTAHYDPATQEFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYTPDGQCRGLHSFLVQIRDPKTLLPMPGVMVGDMGKKLGQNGLDNGFAMFHKVRIPRQNLLDRTGNVTSEGHYHTPFKDVRQRLGASLGSLSSGRISIISISVVNLKLAVIIAIRFSATRRQFGPTDKEEIPVLEYPLQQWRLLPYLAAAYALDHFSKTIFLDLIELQRAGKVGTTVTGRQSSGREIHALASAGKPLASWTAQRGIQECREVVGGHGYLAMNRFGELRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEHPLQDGAHFTSPLKTVNFLEAYPGILGQKFMASSKADWLDSEAPLAAYRWLVCYLLRESHQRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHTHSSSVPPSLRTVLGRLSMLYGLWCLSQHTALLYRGGYISGEQTGKAMEDAILMLCVQLKDDAVALVDAIAPSDFVLGSPIGRADGELYKNLWAAVLQQSGVLERAAWWPEFTANKSVANRLKSQL
Protein: Cysteine and histidine-rich domain-containing protein RAR1 (AtRAR1) (CHORD domain-containing protein RAR1) (Protein PPHB SUSCEPTIBLE 2) (Protein REQUIRED FOR MLA12 RESISTANCE 1) (Q9SE33)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required specifically for plant innate immunity. Is essential for resistance conferred by multiple R genes recognizing different bacterial and oomycete pathogen isolates like avirulent P.syringae or H.parasitica (downy mildew). Contributes additively with SGT1B to RPP5-dependent resistance. Functions as positive regulator of RPS5 accumulation by assisting its stabilization. May function as co-chaperone of HSP90-2 to positively regulate the steady-state accumulation of RPM1 and protect it from SGT1-mediated degradation. Acts as negative regulator of pathogen-associated molecular pattern (PAMP)-triggered immunity.
Interaction partners:
- Protein SGT1 homolog B
- Protein SGT1 homolog A
- Heat shock protein 90-1
- Heat shock protein 90-2
- Heat shock protein 90-5, chloroplastic
- Endoplasmin homolog
- Heat shock protein 90-6, mitochondrial
- Heat shock protein 90-3
- Heat shock protein 90-4
- SKP1-like protein 1A
Sequence:
MEVGSATKKLQCQRIGCNAMFTDDDNPQGSCQFHASGPFFHDGMKEWSCCKQRSHDFSLFLEIPGCKTGKHTTEKPVLAKSVPKHPVAAPTSSPDANAATKDSCSRCRQGFFCSDHGSQPKEQIKQTLNTPGQAEEEKIEPLAPPVQKAVIDINQPQVCKNKGCGQTFKERDNHETACSHHPGPAVFHDRLRGWKCCDVHVKEFDEFMEIPPCTKGWHSSSPDPAV
Protein: Isocitrate dehydrogenase [NAD] subunit, mitochondrial (E9PF84)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|RuleBase:RU361266}.
Interaction partners:
Sequence:
MALKVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFET
Protein: Mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK1) (EC 2.7.12.2) (OsMEK1) (Q5QN75)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- Mitogen-activated protein kinase 2
- mitogen-activated protein kinase kinase kinase
- Mitogen-activated protein kinase 6
- Mitogen-activated protein kinase 1
- mitogen-activated protein kinase kinase kinase
- Mitogen-activated protein kinase 5
- Cyclin-dependent kinase B1-1
- Mitogen-activated protein kinase 12
- mitogen-activated protein kinase kinase kinase
- Os02g0769800 protein
Sequence:
MRGKKPHKELKLSVPAQETPVDKFLTASGTFKDGELRLNQRGLQLISEETADEPQSTNLKVEDVQLSMDDLEMIQVIGKGSGGIVQLVRHKWVGTLYALKGIQMNIQEAVRKQIVQELKINQATQNAHIVLCHQSFYHNGVIYLVLEYMDRGSLADIIKQVKTILEPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNLLVNRKGEVKITDFGVSAVLASSMGQRDTFVGTYNYMAPERISGSSYDYKSDIWSLGLVILECAIGRFPYIPSEGEGWLSFYELLEAIVDQPPPSAPADQFSPEFCAFISSCIQKDPAERMSASELLNHPFIKKFEDKDLDLRILVESLEPPMNISE
Protein: Coiled-coil domain-containing protein 130 homolog (Q09651)
Organism: Caenorhabditis elegans
Interaction partners:
- Pre-mRNA-processing factor 19
- Cell division cycle 5-like protein
- Tr-type G domain-containing protein
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8
- WD_REPEATS_REGION domain-containing protein
- Pre-mRNA-processing factor 17
- Beta-catenin-like protein hmp-2
- Beta-catenin/armadillo-related protein 1
Sequence:
MGERKGQNFYYPPDFNYKTHKSLNGYHGTHALRERAKKIDQGILVIRFEMPFNIWCLGCHNHVGMGVRYNAEKKKIGMYYTTPLHEFRMKCHLCDNYYVIRTDPKNFDYELVEGCSRQELRFDPTDIAQIGAVDRGFTQKLAADAMFKKEHEAEDKDKAATEEGRVDKLEWIQERMRDDFTANSFLRAQFRNEKKSLNETRARDANLRDKLSIGTTQLLPETEEDRRIASMMTRYRDTKTHDDHLESSRDRIESRRIFRRPEETDTPSTSSGSSGGAVPSASERLKATMKAERDKRINASFSTAGTSSATQKLLGIKRKSASSLGVQIKKAAPENSSLQDEEPAVEKPNISNPISLIAQEYGNSSDDSD