Protein: Protein unc-80 homolog (Q9VB11)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the na (narrow abdomen) sodium channel complex. In the circadian clock neurons it functions with na and unc79 to promote circadian rhythmicity.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium leak channel NALCN
- Uncoordinated 79, isoform C
- Mid1, isoform A
Sequence:
MVTNAAGTAATGGATSNTTNNNNLQTNNNSHGANNNNDDFDFDQDSGLQDLGLPVSVQTFLWRQIAPFIRPKLGKLHESTCLFCQHAPGHHESKEACKSFEKVLVQNIQFGLSPPLTKGLGVIPRWRLLQGALPHVMHACAALLYNRVKDMQAIGPVETKLLYTMQWILLYAAEECADDEGGEDLGLGDAAEPKSKSIDQYLFSVPTITLFVYLFAPIIHHLKESDFQNFRLENGIKLWQGMWDNRAPGAPCFTAPVKPKARNLLCAPTPKGSTDVFPARKHSLSADAMSPKADSPQSGISDYGRQDEEGSWVSSPKEFAFPETIPEEASSVEDERVVIFRLPSAPQLMDNSFFTADASLLQQQQSQSRRGSRQSMNSRDKDKVPSTKFEFDQQELMRGASMKEKRSASIEKETDSDKSESIKADVSAATFLDVAVLRCLFISHWQEEGIFWSLQYLYNRLSDIGEEAAITLNQPRKRSNSLPIPQIEISLYQGPGSNSRDSPGSSVVKDYIEIPDPSPTVTACVAEEPQSAPSTTERRGSEKKKRVKMADLRAFVETKMFSKSEKNLEKVGLDTNSANGKTPLQHAEYHRSLDTGEKKLSRSASMISREPASNLIKGKSMPSLRFYRYVEPPKAPRPSQATCPRSTAFYPRNPIITVTEHTPTPSPDYMKRQGSIDSQLDALSNGGSIAGMTGNGGGNGSTGMGSSTTRYRGQMLRSHTDSHIDYTGVDESEAPGSSFYITRDGGIDYEIILLAISNVFKRDPAQVCSLRVLEAGLNICELLIEMGVLKLGEHAHEISMSITRRALQVLGCPHGCNDGVRGPPADFLRNQCQKILSRMLRQAGQRTKRFMQEMVKTSPLPELIDYFHAFLAFCVDPSSLLSPLSQGGYSTNFSGGMSGGAEAQVVGAVFKPLVSRFVEASKDLKGPENIALYGDIRQLVTYVKGAHGGPFRLVALSGILAVTPRPHKKGPSAQTTRVIRHIPQANANQSLQNDDNRSQRRLLLKKRSTSSACASLLETEACEEHYKTSQSPLSNFRRRTTGVRPTLTPRHSERALLSDSTSSSERNSLGRLSGLVRWFRGTPKEASSIDLEIGSLNPEISSTFMRHASLKIQRGRSSDGIGRSIQRAKRRVERRLNRFGGIVKGKKKVGGIEETADFSRRSSSDMCDGPRESEVVILKERKLVPTEPVRVGMLRLSFLLETCAPGSFPDPQLVAAVLDLPQAPLVARATFLLECAHFVHLCNKGQWPAWMKQNVGSYRASGANINLNQMKQQVSQTSARRTHILQRAAGKMFHQWAEMVGARLEEILFTERLQYEAVNASLTDPEKQRELLQQDEEEDFLDETSVNPHGNDCPHSLKLIACVLLFEITAFLRDTYLMLPKTSKLIHRDKPAPWEKVYREANRRWSMALSSMGHSQTSAQSLQSIAAGNDGAGQSERKISFVLHEPDNESENSSNTTLTKEGEEARRPTTSAVRPFLLRRGTATTTGGSFKRRSLKLRRNTKDSKDIETDFNMQSRRKVSSLSDRSDTSEQGMISGGEESPGILSDDQQPESPTDSNENDDTAKNMPWLKAIIDLMSSYNYYCTHKGYCHPFCYKRHMRSCTRLVKATRKVYGEEFGFTFDADHPNVEPTIITSSKPHTSRARSTRKVSEQSSTQTSPSKRKDSLSRKDRISDDPDLEMAEKLAKAFRQEKEKKMQEEPPILKFIRIHIRNLFHFPLATLLKGAVVLTEEMVIEAMPAAWELLLETNHDTATSSAAVFLMGSVKAQNFAFDIMQRALKHKDPDIRIGAIQRYLVLWKCRFHVWPRMEENAHDVTFKVPPGGIEFTLPSPKIGIESLPVVDPPWMPVQQTKDMDVTLNQDRHRSLVTATKSRKMQQTEAIRNALRQQRDKQRAERHSFLITMIPISQQASHEPGMEKLEDHEIEEDLDGTRMSSHLHHAHSLFPSVLCSSVMQIVGCLDDAAIGSDGNAVYEIAYQVIWVCLVEESALFLRYVFERLTRDRQDQMFKLLRHLIRFVPRLPQQAAFALYNSIIGYIMFYVRSSNELKQELVGSALSVLWMVVHSVHGIMFKDLKQILRKEQCDASILLTANVPAAKKIVVHGPADDDYNIPSQFPVQEDTLFCQLLKEALDYYPIDEKNTSHYCLVDYKSSKILNPNWYIRDLYFFKRSQYPEVRLMLMRPEESFLALQKQELTKKFVEIGKVHLTWAILKNVDMVVQRVVFLHEELMKLPSFPRKALEVDLDLHHGGEYGKVLLGLDVLHKFMWVRLIARMFEAMAGNFAYSADIQLFLNVLSGASILHAEDSCIMRYVMATFINAAFNFKNIFSTNGYFMIMPTLLQVYSLHQTNKLITTTIEYAVKQFYLLNRKPFILQMFGSVSAILDTDEDGTYGEAHKVQSSCLFNLLLSLEDPSPDPLNIAELVKEPKPLKAIDFCYHDEDDDVTVLDCITLCVMVVSYSAESTRGYQMLIILEAILPCYLQQIQSPSYIPLQGKSERDIILQLAVAIRTMVHNCEGLAKSYNGPYRNSPEHKGSSQRNCSRGPPCSPGLDFEEETHPKYMTDARTKNMMDSAEDSEMIRTEYRRPRDVLLSVVADFLTKSTVRLAELAKKMPSDTKPTEVLDAKCHIRLADIAHSLLKVSPYDPESMACRGLQRYMQAVLPRAEWSNDTLRNALVTILRRIDKVFLKISKKPSIRRNTDWEAAAGLLKGIHETIIRHSYVLHWQQMKTLISTVQNLIVNEPGIPEGVSSAGAALMSQNPPAFFCSAVVRLVALQVVSPVDCFSLVQICGGSSEFATQEKAEGFLMHLIMPLCLKVCSGRGVSDVGELKMSDVSFLLTAVLNAMSPPAGRTGQAVSQINRVTGDLRAGSLTFTGSRDAKRPARISGSLYQAAFLALRIVCICFESRLSNEWPRIVRVMRDLGRRNEAAPDLWSFMEFVVTHRTPLYIVLLPFILHKISQPPIGDHERHMQFIIRERLRGTPPQGGIKSKGALLLELARELRDLRDELEEKRYDRESSEQKKSDTPAATSAAEAHKSQQRPSLISIFTGTTTGQASHSHVSAVPIDSRSGSGGICTPSDTLSQQTLHPPRESLSSSSTGRDPHTTTSESQSGEADAGSAPTLVGATPSGSGHGSGGGIGTGAASAVPSHLSHSQSLQQAPFKAQPPKLRFVSSVEFRHSSGETSTTPLSPESPAEDSSGDHTRSRLQRSKAASRKTFRLKRSRLTPMEPPSIVTSQEEQAPQAQAKTLGEISWDSVSQTSSTSGYRDNNSLQTGLLSPDGSLGGLTLGRSPSQHSLLMVFEGQDEDTLI