wanglab/gogpt-training-data huggingface dataset:
Protein: AP complex subunit beta (Q9N4F3)
Organism: Caenorhabditis elegans
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00029433}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00029433}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00029433}.
Interaction partners:
- AP-1 complex subunit gamma
- AP-2 complex subunit mu
- AP complex subunit sigma
- AP-2 complex subunit alpha
- Probable clathrin heavy chain 1
- AP complex subunit sigma
- AP-1 complex subunit mu-1-I
- MHD domain-containing protein
- Clathrin light chain
- RAP domain-containing protein
Sequence:
MTDSKYFTTTKKGEIFELKNELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNVELKKLVYLYLMNYAKSQPDLAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVEKITEYLCDPLRRCMKDEDPYVRKTAAVCVAKLHDMNPALVKEQGFVELLNDLLSDANPMVVANAVAALTEMNEQQTVIEVNSQMVNKLLTALNECTEWGQVFILDALAGYTPRDERETQNICERISPRLAHANAAVVLSTVKVLMKLIDMMPADSDFITQLTKKLAPPMVTLLSAEPEIQYVALRNINLIVQKRPDILKQEMKVFFVKYNDPIYVKMEKLDIMIRLAQQNNIAQVLSELKEYATEVDVDFVRKSVRAIGRCAIKVEASSERCVQTLLELIQTKVNYVVQEAVVVIKDIFRKYPNRYESIISALCENLDTLDEPEARASMIWIIGEYAERIDNADELLESFVEGFHDENTQVQLQLLTAVVKLFLKRPGVAQALVQRVLSLATQDSDNPDLRDRGFIYWRLLSADPAAAKNVVLTEKPLISEETDLLEPSLLEQLVCHIGTLASVYHKPPSAFIDPAKAPLRQINPIPAAKFGSSLLDTSSTPNAARNGSAAAPTVIPSQDQVIADLLSLDLNAPAASANTGAFGGAMSGTTSMGGLDDLLGLGGDPMPAAPTNSASYNPFDGLGGLGGAAPAAPPSQQPASIGGLAEIFGSGGFGGSSGITYPKELWLDASKAMGMQVEGTFVRRGGKIFMEMTITNRAMQAISGFALQFNKNSFGLIPVEQVNPAPILPNQSQNYTIACDTTGAVQVTTPLTNLQVAIKNDINAFYFATTVPLLAYFREDGQMEKREFLEEWKSIPEQNEQQFTLQNTHNMNADAICTKLQQNNIHTVARRQVDNQQLLYHSVKYTNNLNVLSELKVNSQTTSITLSLKSKNLMAIANINEVFQALLN
Protein: Zinc finger (C2H2 type) family protein (F4J311)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- C2H2 type zinc finger transcription factor family
- At5g26610
- DNAJ protein JJJ1 homolog
- At2g32600/T26B15.16
Sequence:
MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI
Protein: Semaphorin 3A (F1NVZ5)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MGRRCYLCCLKFPGGARQDGERRGSGSQGPYSGCCSMGWLRGIALLSLGVLLAGRVNCQHVKNNVPRLKLSYKEMLESNNIVNFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFNLVNIKEYQKIVWPVSHSRRDECKWAGKDILRECANFIKVLKTYNQTHLYACGTGAFHPMCTYIEVGSHPEDNIFRMEDSHFENGRGKSPYDPKLLTASLLVDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPRFISAHLIPESDNPEDDKIYFFFRENAIDGEHTGKATHARIGQICKNDFGGHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNSKDPKNPIVYGVFTTSSNIFKGSAVCMYSMTDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDSTKDLPDEVITFARSHPAMYNPVFPINSRPIMIKTDVDYQFTQIVVDRVDAEDGQYDVMFIGTDIGTVLKVVSIPKETWHELEEVLLEEMTVFREPTVISAMKISTKQQQLYIGSATGVSQLPLHRCDVYGKACAECCLARDPYCAWDGSSCSRYFPTAKRRTRRQDIRNGDPLTHCSDLQHHDNPSGQTLEEKIIYGVENSSTFLECSPKSQRAIVYWQFQKQNDDHKVEIKVDDRMIRTEQGLLLRSLQRRDSGIYFCHAVEHGFIQTLLKVTLEVIDTDHLEELLHKEEDGDASKTKDATNSMTPSQKIWYRDFMQLINHPNLNTMDEFCEQVWKRDRKQRRQRPANAQVNTNKWKHLQENKKGRNRRTHEFERAPRSV
Protein: ORF50 (O92608)
Organism: Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Interaction partners:
Sequence:
MAQDDKGKKLRRSCVESFVGLSDELKAQLYQCVLLINDAYETIYDPSDLNRVVEDVCIRIMKECSKLGALCGLFTDINMFNLFCFFRASRMRTKGAAGYNVPCAEASQGIIRILTERILFCTEKAFLTAACSGVSLPPAICKLLHEIYTEMKAKCLGAWRRLVCNRRPIMILTSSLLKLYNTYDTAGLLSEQSRALCLLVFQPVYLPRIMAPLEIMTKGQLAPENFYSITGSAEKRRPITTGKVTGLSYPGSGLMPESLILPILEPGLLPASMVDLSDVLAKPAVILSAPALSQFVISKPHPNMPHTVSIIPFNPSGTDPAFISTWQAASQNMVYNTSTAPLKPATGSSQTVSVKAVAQGAVITATTVPQAMPARGTGGELPVMSASTPARDQVAACFVAENTGDSPDNPSSFLTSCHPCDPNTVIVAQQFQPPQCVTLLQVTCAPSSTPPPDSTVRAPVVQLPTVVPLPASAFLPALAQPEASGEELPGGHDGDQGVPCRDSTAAATAAEATTPKRKQRSKERSSKKRKALTVPEADTTPSTTTPGTSLGSITTPQDVHATDVATSEGPSEAQPPLLSLPPPLDVDQSLFALLDEAGPETWDVGSPLSPTDDALLSSILQGLYQLDTPPPLRSPSPASFGPESPADIPSPSGGEYTQLQPVRATSATPANEVQESGTLYQLHQWRNYFRD
Protein: ShKT domain-containing protein (Q9XVA9)
Organism: Caenorhabditis elegans
Interaction partners:
- TransThyretin-Related family domain
- Yeast DiM Like
- CUB-like domain-containing protein
- Infection Response protein
- CUB-like domain-containing protein
- ShKT domain-containing protein
- C-type lectin domain-containing protein
- ShKT domain-containing protein
Sequence:
MIFRPLLIFVTLFALALCQEDYVEELAENTTTTTEGSTVSSDSSTAGSSEAPCQDDPSTDCASLKNLCTNSKYTPMLKAFCPVTCNMCPGATTPEPPTADPNCHDNSSNCVNWVKNGFCSNCFYKCSDRIKNCAKSCGFCTPGSCKDCTNMKHFMKFIEDPIDLE
Protein: Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' gamma isoform (AtB' gamma) (PP2A, B' subunit, gamma isoform) (Q8RW96)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that negatively regulates brassinosteroid signaling by dephosphorylating and inactivating BRI1 in the cytoplasm. Seems to be functionally connected with CPR5 and may mediate the negative regulation of defense reactions and senescence under low irradiances. May contribute to the epigenetic regulation of defense gene expression. Involved in the control of methoxylation of indole glucosinolates and formation of 4-methoxy- indol-3-yl-methyl glucosinolate in leaves, through direct interaction with indole glucosinolate methyltransferases. Involved in growth regulation and stress signaling. Involved in the regulation of reactive oxygen species (ROS) signaling and maintenance of cellular ROS homeostasis. Required to control the level of ACO3 phosphorylation in the cytoplasm. Regulates hydrogen peroxide metabolism by controlling the abundance of AOX1A and AXO3/AOX1D in leaf mitochondria. May mediate dephosphorylation of CRT1 and promote the degradation of unfolded proteins in endoplasmic reticulum (ER). Involved in the regulation of flowering time by repressing FLC, the main flowering repressor gene.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:19672620, ECO:0000269|PubMed:21571669, ECO:0000269|PubMed:25307043, ECO:0000269|PubMed:26517938}. Nucleus {ECO:0000269|PubMed:19672620}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
- Serine/threonine-protein phosphatase PP2A-2 catalytic subunit
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
- Serine/threonine protein phosphatase 2A regulatory subunit B''beta
- Serine/threonine protein phosphatase 2A regulatory subunit B''alpha
- Probable serine/threonine protein phosphatase 2A regulatory subunit B''gamma
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A gamma isoform
- Aconitate hydratase 3, mitochondrial
Sequence:
MIKQIFGKLPRKPSKSSHNDSNPNGEGGVNSYYIPNSGISSISKPSSKSSASNSNGANGTVIAPSSTSSNRTNQVNGVYEALPSFRDVPTSEKPNLFIKKLSMCCVVFDFNDPSKNLREKEIKRQTLLELVDYIATVSTKLSDAAMQEIAKVAVVNLFRTFPSANHESKILETLDVDDEEPALEPAWPHLQVVYELLLRFVASPMTDAKLAKRYIDHSFVLKLLDLFDSEDQREREYLKTILHRIYGKFMVHRPFIRKAINNIFYRFIFETEKHNGIAELLEILGSIINGFALPLKEEHKLFLIRALIPLHRPKCASAYHQQLSYCIVQFVEKDFKLADTVIRGLLKYWPVTNSSKEVMFLGELEEVLEATQAAEFQRCMVPLFRQIARCLNSSHFQVAERALFLWNNDHIRNLITQNHKVIMPIVFPAMERNTRGHWNQAVQSLTLNVRKVMAETDQILFDECLAKFQEDEANETEVVAKREATWKLLEELAASKSVSNEAVLVPRFSSSVTLATGKTSGS
Protein: Ras GTPase-activating protein 1 (Q3V090)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQGQVLNDTVDGKEIYNTIRRKTKDAFYKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCSLRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLKIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLAHLLSILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNNTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLTLVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGVQQHVLKKLLAITELLQQKQNQYTKTNDIR
Protein: Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Q18496)
Organism: Caenorhabditis elegans
Interaction partners:
- Bifunctional glyoxylate cycle protein
- Probable citrate synthase, mitochondrial
- Aldehyde dehydrogenase
- Aldehyde dehydrogenase domain-containing protein
- Acetyl-CoA C-acetyltransferase
- Aldehyde dehydrogenase
- Acyl-coenzyme A oxidase acox-1.4
- Acyl-coenzyme A oxidase acox-3
- Aldehyde dehydrogenase domain-containing protein
- Acetyl-CoA acetyltransferase homolog, mitochondrial
Sequence:
MSDVRVKFNLANDGEGLDEDIFLPPAPLLAGAHCAGLQSYHDLYRSSINDADEFWRTVSSELHFEQGTSKGLEWNFDSKAGNVFVKFMDGAKTNISYNCLERNIKRGYGNKIAYIFEGNEPTDTSTWTYNELHAQVVQFSAVLRSHGVKRGDVVALYLPMIPELAVAMLACARIGAMHSVVFAGFSAESLAARVVDARCRVLVTADGVFRGAKPIGLKSIADAAAVLASQEDVKVEAIIMVEHLKRVTKPDGVELPKVDYTDITVIYDSEMLKCAGVDSPVEWMDSEDPLFILYTSGSTGKPKGIQHTTAGYMTYAYATTKYTFDAQEDDVYWCTADCGWITGHSYLLYGPLMNGLKGIWYEGVPTYPTPSRMWDVTDKYGVTKLYTSPTAARALMALGNQWLESSSRKTLKVIGTVGEPINPAAWMWLYKQVGLSNVSIVDTYWQTETGGHMITCLPGATPMKPGAAAMPFFGASPVLLDAEGRVIEGPGEGSLCFDRAWPGMMRGIYGDEQRFVKTYLAPFNGYYFTGDGARRDEDGYLWITGRVDDLMNVSGHLLSTAEIESALVAHEKVAEAAVVAAPHDIKGSFPYAFVTLNVGERINEKLVAELKKLVREKIGALAVPDVIQEAPGLPKTRSGKVTRRILRKIAEGSESGIGDTTTLVDESVIKQLISGRSARA
Protein: Glutamate receptor ionotropic, NMDA 3B (GluN3B) (N-methyl-D-aspartate receptor subtype 3B) (NMDAR3B) (NR3B) (Q8VHN2)
Organism: Rattus norvegicus (Rat)
Function: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q91ZU9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q13224}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q91ZU9}. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. {ECO:0000250|UniProtKB:Q91ZU9}.
Interaction partners:
- Glutamate receptor ionotropic, NMDA 2D
- Glutamate receptor ionotropic, NMDA 2B
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2C
- Glutamate receptor ionotropic, NMDA 2A
- Glutamate receptor ionotropic, NMDA 3A
- Glutamate receptor ionotropic, kainate 1
- Glutamate receptor ionotropic, kainate 4
- Disks large homolog 4
- Glutamate receptor 4
Sequence:
MESVRTLWLSVALALAVGSRVVRGHPQPCRVPTRAGASVRLAALLPRAPAARARVLAALATPAPRLPHNLSLELVAVASPTRDPASLARGLCQVLAPPGVVASIAFPEARPELRLLQFLAAATETPVVSVLRREVRTALGAPTPFHLQLDWASPLETILDVLVSLVRAHAWEDIALVLCRVRDPGSLVTLWTNHASQAPKFVLDLSRLDSRNDSLRAGLALLGALEGGGTPVPAAVLLGCSTARAHEVLEAAPPGPQWLLGTPLPAEALPTTGLPPGVLALGETEQHSLEAVVHDMVELVAQALSSMALVHPERALLPAVVNCDDLKTGGSEATGRTLARFLGNTSFQGRTGAVWVTGSSQVHVSRHFKVWSLRRDPLGAPAWATVGSWQDGQLDFQPGAAALRVPSPSGTQARPKLRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSVPRTLRRCCYGYCIDLLERLAEDLAFDFELYIVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRTRDTASPIGAFMWPLHWSMWVGVFAALHLTALFLTLYEWRSPYGLTPRGRNRGTVFSYSSALNLCYAILFGRTVSSKTPKCPTGRFLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPSQGFRFGTVWESSAEAYIKASFPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMGVYHFSGLFVLLCLGLGSALLTSLGEHVFYRLVLPRIRRGNKLQYWLHTSQKIHRALNTGPPEGQQERAEQERSGPKDELPATDGAGRWRRVRRAVERERRVRFLLEPGEAGGDRPWLCSNGPGLQAELRELELRIEAARERLRSALLRRGELRALLGDGTRLRPLRLLHAAPAES
Protein: ATP-dependent helicase rhp16 (EC 3.6.4.-) (DNA repair protein rhp16) (RAD16 homolog) (P79051)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in global genome repair (GGR) via nucleotide excision repair (NER), in conjunction with rhp7, after UV irradiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}.
Interaction partners:
- DNA repair protein rhp7
- Imidazoleglycerol-phosphate dehydratase
- DNA repair protein rad16
- Histidine biosynthesis bifunctional protein his7
- Histidinol-phosphate aminotransferase
- ATP phosphoribosyltransferase
- 1-
- Imidazole glycerol phosphate synthase hisHF
- DNA excision repair protein ckn1
- Mating-type switching protein swi10
Sequence:
MGTSCNKINSNSNKGKENMHFVLDDNGDSKGNASNQQVERDDKLDMETTRWNGKEFEEPLSTNKKLIIQSNNTSSQHSTPPLSISDTSTHTGSSTDNVEANPNTGFSSARKRSLRSSNLKKKFVPLSSPEESNESEFIDDDESDEVASIIDIKEDETFDSKVEIPEAAPSSSTESDEESIPLSYQSKRRRVSARASSSASSSSRTQAKSIPSHERTHYRLIRQHPELEHVWEKLEEEAPREVKQIEQPKELVLNLLPFQREGVYWLKRQEDSSFGGGILADEMGMGKTIQTIALLLSEPRGKPTLVVAPVVAIMQWKEEIDTHTNKALSTYLYYGQARDISGEELSSYDVVLTSYNVIESVYRKERSGFRRKNGVVKEKSLLHQMEFYRIILDEAHGIKSRTCNTARAVCGLRTTRKICLSGTPLQNRIGELFSLLRFLRADPFAYYYCLQCECKSLHWRFSDRSNCDECGHKPMSHTCYFNAEMLKPIQKFGYEGPGKLAFKKVHSLLKHIMLRRTKLERADDLGLPPRVVEVRKDLFNEEEEDVYQSLYMDSKRKFNTYLAEGVVLNNYANIFQLITRMRQMADHPDLVLASKRKTVDIENQENIVCKICDEVAQDAIESRCHHTFCRLCVTEYINAAGDGENVNCPSCFIPLSIDLSAPALEDFSEEKFKNASILNRIDMNSWRSSTKIEALVEELYLLRKKDRTLKSIVFSQFTSMLDLIHWRLRKAGFNCVKLDGGMTPKARAATIEAFSNDINITIFLVSLKAGGVALNLTEASQVFMMDPWWNGAVQWQAMDRIHRIGQKRPIKVITLCIENSIESKIIELQEKKAQMIHATIDQDEKALNQLSVEDMQFLFSN
Protein: Glycosyltransferase 6 (AtGT6) (EC 2.4.-.-) (Q9SZG1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable glycosyltransferase that may be involved in the biosynthesis of xyloglucan.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Probable xyloglucan galactosyltransferase GT12
- Probable xyloglucan galactosyltransferase GT15
- Probable xyloglucan galactosyltransferase GT13
Sequence:
MGKPGGAKTRTAVCLSDGVFFLAGAFMSLTLVWSYFSIFSPSFTSLRHDGKPVQCSGLDMQFDPSEPGFYDDPDLSYSIEKPITKWDEKRNQWFESHPSFKPGSENRIVMVTGSQSSPCKNPIGDHLLLRCFKNKVDYARIHGHDIFYSNSLLHPKMNSYWAKLPVVKAAMLAHPEAEWIWWVDSDAIFTDMEFKPPLHRYRQHNLVVHGWPNIIYEKQSWTALNAGVFLIRNCQWSMDLIDTWKSMGPVSPDYKKWGPIQRSIFKDKLFPESDDQTALIYLLYKHKELYYPKIYLEAEYYLQGYWIGVFGDFANVTERYLEMEREDDTLRRRHAEKVSERYGAFREERFLKGEFGGRGSRRRAFITHFTGCQPCSGDHNPSYDGDTCWNEMIRALNFADNQVMRVYGYVHSDLSKTSPLQPLPFDYPNEAW
Protein: DNA repair protein rhp57 (RAD57 homolog) (Q9UUL2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in recombination DNA repair and in the repair of gamma-ray-induced damage.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DNA repair protein rhp55
- Mating-type switching protein swi5
- DNA repair and recombination protein rad22
- ATP-dependent DNA helicase srs2
- Swi5-dependent recombination DNA repair protein 1
- DNA repair protein rhp54
- Meiotic recombination protein dmc1
- DNA repair protein rhp51
- ATP-dependent DNA helicase hus2/rqh1
- Crossover junction endonuclease mus81
Sequence:
MDISNYVDNFYFDEKIASAFELGEVSTVDLLTLDITELERRTHCSQSELLQLIEQISLLLQPVRCSASKVTSKYLTTGDVKLDETLHGGIPVGQLTEICGESGSGKSQFCMQLCLMVQLPLSLGGMNKAAVFISTESGLETKRLFELARYLPERYPKADKKDIIIKNPGDRVYTILCPDLESQEHIIQYQLPILFNRDKIGLVILDSVASNYRAELRYNRSKSHFRDLDNIAKRGNQLGKLAMTLRTLAHQHEAAVVIANQVSDRIPRDYDAIGLFSLDYQSQWFSGWDDTDPNPKIPSLGLVWTNNISTRLALIKKTDSATNNSGRIFRVVYSPNSPRLDVRICIGSVGIYSC
Protein: Rhotekin (Q8C6B2)
Organism: Mus musculus (Mouse)
Function: Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures (By similarity).
Interaction partners:
- Transforming protein RhoA
- Microsomal glutathione S-transferase 1
- Rho-related GTP-binding protein RhoC
- Rho-related GTP-binding protein RhoB
- Protein lin-7 homolog B
- Rho guanine nucleotide exchange factor 12
- Rho-associated protein kinase 2
- Rhodopsin
Sequence:
MFSRNHRSRITVARGSALEMEFKRGRFRLSFFSESPEDTELQRKLDHEIRMRDGACKLLAACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQVLEKTGRRPSDSVQPAQHSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQIGEQIQDTEMVLVDRTLTDISFQNNVLFAEAEPDFELRLELYGACVEEEGALAGAPKRLATKLSSSLGRSSGKRVRASLDSAGASGNSPVLLPTPAVGGPRFHLLAHTTLTLEEVQDGFRTHDLTLTSHEENPAWLPLYGSVCCRLAAQPLCMIQPTASGALRVQQAGELQNGTLVHGVLKGTNLFCYWRSEDADTGQEPLFTIVINKETRVRAGELEQAPEWPFTLSISNKYGDDEVTNTLQLESREALQNWMEALWQLFFDMSQWRHCCDEVMKIETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILAQREGTRLEPSPPWLAMFTDQPALPSSCSPASVAPVPTWMQPLPWGRPRTFSLDAAPADHSLGPSRSVAPLPPQRSPKSRGFYSKSQLGPWLQSPV
Protein: Galactose oxidase/kelch repeat superfamily protein (Similarity to unknown protein) (Q9FM30)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSLMLQKNQARGTRASLSQFEPRKLLIASTKPTIPDLNAEPCSDSEEEETVENLTSLAPQDAHNGLPKLMFDLEVEIFSRLSCFQYWKLNLLNKQFSQLLQSREIFKVRRERGLVQPYVLMFSSGETCWVMFDKGFKNFRQLPEIPSDFCFFYGDKETITAGTHLIVIGREEKRIVVWRYELEVNKWINDTEMITPRVMYASASRGTDAFFAGGIKTSENGGPDVVNVAERYNSDTKTWKAMKAMHKRRKFSSGCFLRGKFYALGGRDENDVYLTCGESYDELTDSWKLIPDMLKGMTFMNPQSPPLIAVVKDNLYLLETWLNELWVYDINANVWKNLGVVPVKANAALGWGVAFKSVGDRILVIGASVTKSWDNKMSVYTCCPFPKVEKITWEETSCDCVQLGHFIRNCCVMLA
Protein: Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type) (P48302)
Organism: Mus musculus (Mouse)
Function: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Essential component in the normal development of two neuronal crest-derived cell lineages.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P24530}; Multi-pass membrane protein. Note=internalized after activation by endothelins. {ECO:0000250|UniProtKB:P24530}.
Interaction partners:
- Endothelin-3
- Endothelin-1
- Endothelin-2
- Endothelin-1 receptor
- Guanine nucleotide-binding protein G
- Angiotensinogen
- Kininogen-1
- Guanine nucleotide-binding protein subunit alpha-11
- Guanine nucleotide-binding protein G
- Prothrombin
Sequence:
MQSPASRCGRALVALLLACGFLGVWGEKRGFPPAQATLSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRGAGVPPRSFPPPCQRNIEISKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDMITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAVFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPHRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
Protein: Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog) (P54254)
Organism: Mus musculus (Mouse)
Function: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity). May be involved in RNA metabolism (By similarity). In concert with CIC and ATXN1L, involved in brain development.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P54253}. Nucleus {ECO:0000269|PubMed:9778246}. Note=Colocalizes with USP7 in the nucleus. {ECO:0000250|UniProtKB:P54253}.
Interaction partners:
- Ubiquilin-4
- Histone acetyltransferase KAT5
- Protein capicua homolog
- Nuclear receptor corepressor 2
- Ataxin-1-like
- Recombining binding protein suppressor of hairless
- Splicing factor 45
- Pumilio homolog 1
- Pumilio homolog 2
- Ataxin-2
Sequence:
MKSNQERSNECLPPKKREIPATSRPSEEKATALPSDNHCVEGVAWLPSTPGIRGHGGGRHGSAGTSGEHGLQGMGLHKALSAGLDYSPPSAPRSVPTANTLPTVYPPPQSGTPVSPVQYAHLSHTFQFIGSSQYSGPYAGFIPSQLISPSGNPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQAPGHKVEPPPQQHLSRAAGLVNPGSPPPPTQQNQYIHISSSPQSSGRATSPPPIPVHLHPHQTMIPHTLTLGPSSQVVVQYSDAGGHFVPRESTKKAESSRLQQAMQAKEVLNGEMEKSRRYGASSSVELSLGKASSKSVPHPYESRHVVVHPSPADYSSRDTSGVRGSVMVLPNSSTPSADLEAQQTTHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGGLPQHLVIPGNQPLLIPVGSPDMDTPGAASAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPTTASPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEESHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKQAKTDSLAGSRHRYAEQENGINQGSAQVLSENGELKFPEKIGLPAAPFLSKIEPSKPTATRKRRWSAPETRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
Protein: Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase) (P0A858)
Organism: Escherichia coli (strain K12)
Function: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00147, ECO:0000305}.
Interaction partners:
- Phosphoglycerate kinase
- Glyceraldehyde-3-phosphate dehydrogenase A
- Glucose-6-phosphate isomerase
- Enolase
- Fructose-bisphosphate aldolase class 2
- D-erythrose-4-phosphate dehydrogenase
- ATP-dependent 6-phosphofructokinase isozyme 1
- Transketolase 1
- Transaldolase B
- 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Sequence:
MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
Protein: HL01082p (Q95S22)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MFGPSPDWVVGISGLDLCTEDCSWKESMDFDLFPWDAGTDSGISYMSPNSETQPPERMYRITTMYPEDPRAPFYNPKSREMTPLAKLYLRREKIVSRNCDDEFLQALQLEVSDDAEEQDTRAECRVGDYSAWSPCSVSCGKGIRMRSRQYLYPAAADQNKCARQLVAKEMCVAAIPECADGPAQSKDRDDDEGENLANSQSLVGSNGEGAGLCKTSPWSVWSECSASCGIGITMRTRTFVNHLGRKRCPHITIVEKNKCMRPDCTYEQVELPDPQCPTSQWSDWSPCSSTCGRGVTIRTRLLLLENGPDKESCTQRMELHQQKECVNPIDCHINAEQAKDICVQAPDPGPCRGTYMRYAYDPQNQHCYSFTYGGCRGNRNNFLTENDCLNTCNVLRSPYSSRVDQPRACVLSDWSVWSPCSVSCGVGVSESRRYVVTEPQNGGQPCSKRLVKSRSCAMPAC
Protein: Galactokinase 1 (A0A8I6ARU6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAAWRPPRVEELLAEARRAFMEEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELVTVMVGSPRTDGLVSLLTTSKDADEPQRLQFPLPSAQWSLEPGIPQWANYVKGVIQYYPASPLCGFSAVVVSSVPLGGGLSSSASLEVATYAFLQQLCPDSGSIAARAQVCQRAEHSFAGVPCGIMDQLIALLGQKGYALLIDCRSLETSLVPLSDPKLTVLITNSNVRHSLASSEYPIRRRQCEEVAQALGKESLREVRMEELEAGRELMSKEGFRRARHVVSEIRRTAQGAAALSRGDYKAFGRLMVESHYSLRDDYEVSCPELDLLVEAALSVPGVYGSRMTGGGFGGCTVTLLEASVAPLVMHHIQEQYSGTATFYLTQAADGAQAGALRRPSEMNFHWAAGLALANLFGKKCHSAQKTPADKAPPSPGSRRWSSLPH
Protein: MAGE family member A11 (C9J2X2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSKVSTMFSEDDFQSTERAPYGPQLQWSQDLPRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFM
Protein: Tetratricopeptide repeat protein 36 (TPR repeat protein 36) (A8E7I5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- 4-hydroxyphenylpyruvate dioxygenase
- Fumarylacetoacetase.
Sequence:
MASAHDRAVLQAIFNPTSPIGDVPGLNQEEELMDDDSAFDPELVKQVKDLELQGVSSAESGDLPAALQHFNQAISVLPQRASAYNNRAQTKRLLGDTKGAVEDLEHAISLSNGKGRSACQALVQRGLLLRLSGHDEEARLDFERAAALGSEFARQQAVILNPYAALCNRMLSEVISKLRNPEVSEMQ
Protein: Mitotic spindle assembly checkpoint protein MAD2B (B1AK45)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIK