wanglab/gogpt-training-data huggingface dataset:
Protein: Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50) (Q9BQA1)
Organism: Homo sapiens (Human)
Function: Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Subcellular location: Nucleus {ECO:0000269|PubMed:17437848, ECO:0000269|PubMed:21081503}. Cytoplasm {ECO:0000269|PubMed:17437848, ECO:0000269|PubMed:21081503, ECO:0000269|PubMed:27337956}. Note=Nuclear in Leydig cells and cytoplasmic in germ cells during fetal testicular development. In adult testis, predominantly nuclear. Subcellular location varies from nuclear to cytoplasmic in various tumors (PubMed:17437848). {ECO:0000269|PubMed:17437848}.
Interaction partners:
- Methylosome subunit pICln
- Protein arginine N-methyltransferase 5
- Small nuclear ribonucleoprotein Sm D3
- Small nuclear ribonucleoprotein-associated proteins B and B'
- Serine/threonine-protein kinase RIO1
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein Sm D2
- Protein arginine N-methyltransferase 1
- Small nuclear ribonucleoprotein E
- Histone H4
Sequence:
MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWLFKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFCKYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLVDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE
Protein: Protein transport protein SEC23 E (AtSEC23E) (Protein transport protein SEC23 A) (AtSec23A) (Q9LUG1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:P15303}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P15303}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}. Membrane {ECO:0000250|UniProtKB:P15303}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}.
Interaction partners:
Sequence:
MAETANTDLEGIDGVRMTWNVWPHSKAEASKCVIPLAACISPIRRHADIPTLPYAPLRCRTCSAALNAYAQVDFTAKLWICPFCYQRNHFPPHYHVISETNLPGELYPQYTTVEYTLPPPVANGEGLVDPPVFVFVLDTCMIEEELDFAKSALKQAIGLLPENALVGFVSFGTQAHVHELGFSEMSKVFVFKGDKEISKDQILDQLGLGGSSRRGGSKGPQNGFPSSGLNRFLLPASECEFTLNSLLDELQSDQWPVKPGHRSQRCTGVALSVAAGLLGACLPGTGARIVALIGGPCTEGPGTIVSKDLSDPVRSHKDLDKDAAPYYKKAVKFYDSIAKQLVTQGHVLDLFASALDQVGVAEMKVAVERTGGLVVLSESFGHSVFKDSFKRVFEDGDQALGLCFNGTLEICCSQDIKIQGAIGPCSSLEKKGASVADTVIGEGNTSAWRLCGLDKTTCLTIFFDISSSGSNTPGAANPQFYLQFLTSYQNPEGQTLLRVTTVCRQWIDSAVSSEELVQGFDQETAAVVMARLASLKMESEEGFDATRWLDRNLIRLCSKFGDYRKDDPASFTLNPYFSLFPQFIFNLRRSQFVQVFNNSPDETAYFCMLLNRENISNATVMIQPSLTTYSFNSPAEPALLDVASIAADRILLLDAYFSVVVFHGMTIAQWRNMGYHHQPEHQAFAELLQAPQEDSQMIVRERFPVPRLVVCDQHGSQARFLLAKLNPSATYNNANEMSTGSDVIFTDDVSLQVFFEHLQKLVVQS
Protein: Annexin (O82090)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MATLTVPTTVPSVSEDCEQLRKAFSGWGTNEGLIIDILGHRNAEQRNLIRKTYAETYGEDLLKALDKELSNDFERLVLLWALDPAERDALLANEATKRWTSSNQVLMEIACTRSANQLLHARQAYHARYKKSLEEDVAHHTTGDFRKLLLPLVSSYRYEGEEVNMNLAKTEAKLLHEKISDKAYSDDDVIRVLATRSKAQINATLNHYKNEYGNDINKDLKADPKDEFLALLRSTVKCLVYPEKYFEKVLRLAINRRGTDEGALTRVVCTRAEVDLKIIADEYQRRNSVPLTRAIVKDTHGDYEKLLLVLAGHVEN
Protein: UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (O70199)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (By similarity). Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Required for proper brain and neuronal development (By similarity).
Interaction partners:
- UDP-glucuronic acid decarboxylase 1
- UDP-glucose 4-epimerase
- UTP--glucose-1-phosphate uridylyltransferase
- dTDP-D-glucose 4,6-dehydratase
- UDP-glucuronosyltransferase 1A1
- UDP-glucuronosyltransferase 2B15
- UDP-glucuronosyltransferase 2B37
- UDP-glucuronosyltransferase 2B1
- UDP-glucuronosyltransferase
- UDP-glucuronosyltransferase
Sequence:
MVEIKKICCIGAGYVGGPTCSVIARMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCESTGADVEEVATAIGMDQRIGNKFLKASVGFGGGCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDMFKELDYERIHKRMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYTPGEIPKFSLQDPPNKKPKV
Protein: HCO3-transporter family (A8MS82)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MEETFVPFEGIKNDLKGRLMCYKQDWTGGFKAGFRILAPTTYIFFASAIPVISFGEQLERSTGNSAKSFYLALFQLRNLKLDSEIFADGVLTAVQTLASTAICGMIHSIIGGQPLLILGVAEPTVIMYTFMFNFAKARPELGRDLFLAWSGWVCVWTALMLFVLAICGACSIINRFTRVAGELFGLLIAMLFMQQAIKGLVDEFRIPERENQKLKEFLPSWRFANGMFALVLSFGLLLTGLRSRKARSWRYGTGWLRSLIADYGVPLMVLVWTGVSYIPAGDVPKGIPRRLFSPNPWSPGAYGNWTVVKEMLDVPIVYIIGAFIPASMIAVLYYFDHSVASQLAQQKEFNLRKPSSYHYDLLLLGFLTLMCGLLGVPPSNGVIPQSPMHTKSLATLKYQLLRNRLVATARRSIKTNASLGQLYDNMQEAYHHMQTPLVYQQPQGLKELKESTIQATTFTGNLNAPVDETLFDIEKEIDDLLPVEVKEQRVSNLLQSTMVGGCVAAMPILKMIPTSVLWGYFAFMAIESLPGNQFWERILLLFTAPSRRFKVLEDYHATFVETVPFKTIAMFTLFQTTYLLICFGLTWIPIAGVMFPLMIMFLIPVRQYLLPRFFKGAHLQDLDAAEYEEAPALPFNLAAETEIGSTTSYPGDLEILDEVMTRSRGEFRHTSSPKVTSSSSTPVNNRSLSQVFSPRVSGIRLGQMSPRVVGNSPKPASCGRSPLNQSSSN
Protein: ATP-binding cassette sub-family A member 2 (A0A087WXK5)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGRKTSRVQQGPPRSPACSAHGERSWGLEFPPFRWLLGIAGRTHLAALPPFQWVLAFEIFIPLVLFFILLGLRQKKPTISVKEVAFYTAAPLTSAGILPVMQSLCPDGQRDEFGFLQYANSTVTQLLERLDRVVEEGNLFDPARPSLGSELEALRQHLEALSAGPGTSGSHLDRSTVSSFSLDSVARNPQELWRFLTQNLSLPNSTAQALLAARVDPPEVYHLLFGPSSALDSQSGLHKGQEPWSRLGGNPLFRMEELLLAPALLEQLTCTPGSGELGRILTVPESQKGALQGYRDAVCSGQAAARARRFSGLSAELRNQLDVAKVSQQLGLDAPNGSDSSPQAPPPRRLQALLGDLLDAQKVLQDVDVLSALALLLPQGACTGRTPGPPASGAGGAANGTGAGAVMGPNATAEEGAPSAAALATPDTLQGQCSAFVQLWAGLQPILCGNNRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHLMTSNPKILYAPAGSEVDRVILKANETFAFVGNVTHYAQVWLNISAEIRSFLEQGRLQQHLRWLQQYVAELRLHPEALNLSLDELPPALRQDNFSLPSGMALLQQLDTIDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQDNVTVFASVIFQTRKDGSLPPHVHYKIRQNSSFTEKTNEIRRAYWRPGPNTGGRFYFLYGFVWIQDMMERAIIDTFVGHDVVEPGSYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMKTMGLNNAVHWVAWFITGFVQLSISVTALTAILKYGQVLMHSHVVIIWLFLAVYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLGSKYFALYEVAGVGIQWHTFSQSPVEGDDFNLLLAVTMLMVDAVVYGILTWYIEAVHPGMYGLPRPWYFPLQKSYWLGSGRTEAWEWSWPWARTPRLSVMEEDQACAMESRRFEETRGMEEEPTHLPLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGTYGDGYRLTLVKRPAEPGGPQEPGLASSPPGRAPLSSCSELQVSQFIRKHVASCLLVSDTSTELSYILPSEAAKKGAFERLFQHLERSLDALHLSSFGLMDTTLEEVFLKVSEEDQSLENSEADVKESRKDVLPGAEGPASGEGHAGNLARCSELTQSQASLQSASSVGSARGDEGAGYTDVYGDYRPLFDNPQDPDNVSLQEVEAEALSRVGQGSRKLDGGWLKVRQFHGLLVKRFHCARRNSKALFSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQPRGNFIPYANEERREYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPANGSLGPTLNLSSGESRLLAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPASPDEDLQAWNVSLPPTAGPEMWTSAPSLPRLVREPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTGDILTDITGHNVSEYLLFTSDRFRLHRYGAITFGNVLKSIPASFGTRAPPMVRKIAVRRAAQVFYNNKGYHSMPTYLNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFIIVAMSFVPASFVVFLVAEKSTKAKHLQFVSGCNPIIYWLANYVWDMLNYLVPATCCVIILFVFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLLQLFEHDKDLKVVNSYLKSCFLIFPNYNLGHGLMEMAYNEYINEYYAKIGQFDKMKSPFEWDIVTRGLVAMAVEGVVGFLLTIMCQYNFLRRPQRMPVSTKPVEDDVDVASERQRVLRGDADNDMVKIENLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKDEARVVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKSSQSVKDVVRFFNRNFPEAMLKERHHTKVQYQLKSEHISLAQVFSKMEQVSGVLGIEDYSVSQTTLDNVFVNFAKKQSDNLEQQETEPPSALQSPLGCLLSLLRPRSAPTELRALVADEPEDLDTEDEGLISFEEERAQLSFNTDTLC
Protein: Zinc finger protein on ecdysone puffs (P41073)
Organism: Drosophila melanogaster (Fruit fly)
Function: May play a role in the process of early and late gene activation, or possibly in RNA processing, for a defined set of developmentally regulated loci.
Subcellular location: Nucleus {ECO:0000269|PubMed:1899840}. Chromosome {ECO:0000269|PubMed:1899840}. Note=It is associated with the active ecdysone-regulated loci on polytene chromosomes, and on some heat shock-induced puffs. Its distribution pattern follows the changes of puffing patterns in the developmental program, or following heat shock.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein 87F
- Protein no-on-transient A
Sequence:
MVSVKVNGNPQNRLVNNAKVNGNMAFRGNQNRNRNFGGGNNNYGGPMGANRMGGMNMSPWESQNPGGGQFGNNMRQGGGQMNAQAINLANNLLNNLFRNQNPPSLLDLPRGGGGMGNRNQRGGPMVSRGGGAGNRLNNRRGQGGGFQNRGATGSGPKPPPKQGGGGIRKQNAFDRAKKLLAKNANQNKKKEPTPGEKKIESPTKESPYASVPNDMFYCHLCKKHMWDANSFENHIKGRTHLMMREGIEESYRLKANMIRQEAKIAEQLKSIEFDRLKRMGKSKQRQLDYCTMCDLNFHGHISTHRKSEGHLQLKKFLHPKCIECNKEFATRIDYDTHLLSAEHLKKAAENNTKVGERKRQTLPISTEEEETRDLRLPQKRKKKPVKKEGEAADGEAKKEGAGDGEGAEGDEAEGEEAKEGEEAADETKEGDELNESQEEEEVALPVDPEDCILDFNDGDEIPSEVDTRLPKYNWQRAVGPGLISKLECYECSVCSKFFDTEVTAEIHSRTATHHRNFLKFINEKSSDTKIAQKRAAAALEENERKKRKVEEAEAPAAEGAAEETTEGAEGELYDPSEATGDDEDVEMVDDNAEGEGEGEGDEEAEAEVEEDGAGQDNGEEEMEAQEEEGQEGEQEPEPEPAPVQTPAPAEPAPPAKTPAKTPTKAAAPAAVASPAAAATSADASPSPAKKATPARAAAGAKATPQRQRARGRYNRY
Protein: Respiratory burst oxidase homolog protein A (EC 1.11.1.-) (EC 1.6.3.-) (NADPH oxidase RBOHA) (StRBOHA) (Q948U0)
Organism: Solanum tuberosum (Potato)
Function: Calcium-dependent NADPH oxidase that generates superoxide. Involved in the rapid and transient phase I oxidative burst induced by pathogen infection.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16551687}; Multi-pass membrane protein {ECO:0000269|PubMed:16551687}.
Interaction partners:
- non-specific serine/threonine protein kinase
- Calcium-dependent protein kinase 4
- Calcium-dependent protein kinase 5
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
Sequence:
MRGLPGHERRWTSDTVSSGKDLSGESSPGTDSGNISGFASEEFVEVILDLQDDDTIILRSVEPATVINIDASDPATGVGIGGVSIETPASLTSTSGTRSPTMRRSTSNKLRQFSQELKAEAVAKAKHFSQELKAELRRFSWSHGHASRTFSPASFFQNAVVGTGNGVDSALAARALRRQRAQLDRTRSSAHKALRGLKFISNNKTNGWNEVENNFAKLAKDGYLYRSDFAQCIGMKDSKEFALELFDALSRRRRLKVDKISKEELYEYWSQITDQSFDSRLQIFFDMVDKNEDGRIGEEEVKEIIMLSASANKLSRLKEQAEEYAALIMEELDPERLGYIELWQLETLLLQKDTYLNYSQALSYTSQALSQNLQGLRKRSPIRRMSTKLVYSLQENWKRIWVLVLWILIMIGLFLWKFYLYKQKSAFQVMGYCLLTAKGAAETLKFNMALILLPVCRNTITFLRSTKLSCFVPFDDNINFHKTVAAAIVTGIILHAGNHLVCDFPKLIHANNTNYQKYLVNDFGPSQPQYIDLVKGVEGVTGIIMVILMAIAFTLATRWFRRSLIKFPKPFDRLTGFNAFWYSHHLLIIVYIVLIIHGTFLYLVHNWYSKTTWMYLAVPVLLYAGERTLRFFRSGLYTVRLLKVAIYPGNVLTLQMSKPPQFRYKSGQYMFVQCPAVSPFEWHPFSITSAPGDDYLSIHIRQLGDWTQELKRVFSEACEQPEAGKSGLLRADENTKTSLPKLLIDGPYGAPAQDYRKYDVLLLVGLGIGATPFISILKDLLKNIVTMEEQADLVSDFSGNSDMSAATSEQPALNKISPKKRKSTLKTTNAYFYWVTREQGSFDWFKGVMNEVAELDQRGVIEMHNYLTSVYEEGDARSALITMVQALNHAKNGVDIVSGTSVRTHFARPNWRKVFSKTLTKHANARIGVFYCGAPILAKELSKLCKEFNQKGTTKFEFHKEHF
Protein: Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10) (P16371)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta.
Subcellular location: Nucleus.
Interaction partners:
- Protein pangolin, isoform J
- C-terminal-binding protein
- Protein hairless
- Histone deacetylase HDAC1
- Protein hairy
- Suppressor of hairless protein
- Enhancer of split m8 protein
- Brinker
- Protein sine oculis
- Enhancer of split m7 protein
Sequence:
MYPSPVRHPAAGGPPPQGPIKFTIADTLERIKEEFNFLQAQYHSIKLECEKLSNEKTEMQRHYVMYYEMSYGLNVEMHKQTEIAKRLNTLINQLLPFLQADHQQQVLQAVERAKQVTMQELNLIIGHQQQHGIQQLLQQIHAQQVPGGPPQPMGALNPFGALGATMGLPHGPQGLLNKPPEHHRPDIKPTGLEGPAAAEERLRNSVSPADREKYRTRSPLDIENDSKRRKDEKLQEDEGEKSDQDLVVDVANEMESHSPRPNGEHVSMEVRDRESLNGERLEKPSSSGIKQERPPSRSGSSSSRSTPSLKTKDMEKPGTPGAKARTPTPNAAAPAPGVNPKQMMPQGPPPAGYPGAPYQRPADPYQRPPSDPAYGRPPPMPYDPHAHVRTNGIPHPSALTGGKPAYSFHMNGEGSLQPVPFPPDALVGVGIPRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVYEVIY
Protein: Ribonucleoside-diphosphate reductase small chain C (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase TSO2 subunit) (Ribonucleotide reductase small subunit C) (Q9LSD0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Involved in DNA damage repair and programmed cell death inhibition.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21614643}. Nucleus {ECO:0000269|PubMed:21614643}. Note=Cytoplasmic in adult cells, and nuclear in meristematic regions and in all tissues following DNA damage. The nuclear exclusion is dependent on CSN7.
Interaction partners:
- Ribonucleoside-diphosphate reductase large subunit
- Guanylate kinase 3, chloroplastic
- Guanylate kinase 2
- Guanylate kinase 1
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase II, chloroplastic
- Nucleoside diphosphate kinase 1
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- UMP-CMP kinase 3
- Probable UMP-CMP kinase 1
Sequence:
MPSMPEEPLLTPTPDRFCMFPIHYPQIWEMYKKAEASFWTAEEVDLSQDNRDWENSLNDGERHFIKHVLAFFAASDGIVLENLASRFMSDVQVSEARAFYGFQIAIENIHSEMYSLLLDTYIKDNKERDHLFRAIETIPCVAKKAQWAMKWIDGSQTFAERIIAFACVEGIFFSGSFCSIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLLYTLLKTKLSEERVKSIVCDAVEIEREFVCDALPCALVGMNRDLMSQYIEFVADRLLGALGYGKVYGVTNPFDWMELISLQGKTNFFEKRVGDYQKASVMSSVNGNGAFDNHVFSLDEDF
Protein: Polyprotein (X5ICX9)
Organism: Wheat yellow mosaic virus
Subcellular location: Host cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00034108}. Virion {ECO:0000256|ARBA:ARBA00004328}.
Interaction partners:
Sequence:
MEQTAAPTAARHATHTNSAQEQPPVSPMNLSANFVAPELFYASNVEKIKSIIRMRSTTRIIDAISRDFELVAFLILSPAHLMQLETTLRCEMKSSIVPIANSDAGFETCAVLKTALDGMKYHFGTTTLEQGWTSMMRHADSCLQESSSSAVAMLQTQVQKVGSLLISGKNRVESCELYVLHLTARAFRTEYGLKGTCFGEHCALLHDLKACVCGTVPKEFLWAKTKKHSMFTIPEWIARTPTDCFMLCLRAIPIFRRCTMAMSLLYWSCVATVNFPSVMAFLFKRQFTKYIAHSFAKHSIYFLMLGIVALLWAFRTYASKNPKIALQARSANEKEKKLMMLLASAVGITYLFDYDIAEALGNSLHKISRLSSYLMDDHQGIASRMFGASYGLQAGDNVEDAVTTIISDLLSVTFQIVEEDTTAGVLEEVSDTTFSSWVSVNTIAGRNMSRPLQYPVNQTYPLTPMNVLLQAQAMVDSDNCWSMVVGHTGSGKSTYLPVQYSNYLAKKLDRRQQILVCEPTQAATENVCSGIAANLGRAVYGRHEGWSRMGDHCIQVMTYGSALQCHAMDPGFISTFDAIFLDEAHDVKEHSLVFESICNNFKSVRKFYVSATPRDGSSCPDATRKFPLTVQQSVCDSYKKFIAAQGGDDLLDVTKYDTVLVFLAGRPECVKAANAWNASITGEKRAFSLSSDNFATDFAMLTERLKTHKTIIFTTNIIETGVTLSVDCVVDFGYTMRPSLDLNHKTLRLERRRVTANERKQRIGRAGRLKEGHAIVCGDEDRSVNVVSPDVLYGAALLSFKHNVPFYMNDTFESSWLEGITKSQADTMTIFKLPIFLTRDLVNSDGSVAKEFLDILKKHQFTTSDIKQAPHSIARHLFPTWASYFALFQSINYGEEKDEIPSNLRHARVPFSISTLSKFDWNALALACEQHRPTVMSSFQGLDQPARVVTLQTNSANILGSIAHLCNMRNNYKALIDSNNHVKQSMATNVMFKWFSSSRITADLDRNLSRCLANLSVVETTISALKQISAGNSQVMASPILQSHLENIIELQSNDMLTDETLSNALGIFNPKTNLFLLLATKGFKLVYVICLLIFINLIYRLLSHWRAWLKNKNDNVNPDALTNTMTVQEGSEILKEVLKMTPAMRREVTKDMKVAVADNNSTFSFVFPDEHIDLEGKGNKYRPREDARLMYSTRDDATFDTWNEKAKEKRKKISDRAEPEMKQPYQKRPYYNFYDLQTDSNILEAIFYTTEGDEFFRTANPNKDMHSVAEKLKAFLDTKPIIGRHQRQLLEETAQVVIKDDKGTAHRMDISTHNPNTLKNNGSGRVGYDEHRGDFRQESPALESPYELEAEFGNSKDEVMLEASTGILLSQVSVDVATRIGRISIGTFNVNCFLYSDWILAPAHFQDRNGAVTIEFPDQTVSTTTDNLNAHGVKRFYGLDLIAIRRPPSLRPEKKLVKAFAITEPVLAQMVFIDSQGIRKFSQSDWIRQEAGSNRWSHKISTQNGMCGCPVLDVGKNRLIGIHVATNRTTGRNEFQPFTREAVDFINGPGNKVPFSPWIFNRPACGYKQGEATFASRTIQNQASDTLSKINNSILGFGSDLKGQLVQPVTPALRTRFEALFGGGSFELVGTMNKGLIDKHTIVGENDNVHDFMREHPTFAWLQGFMDEYAPSVLNYSAYYKDLCKYNRKKHQLSFNPHELRSATAGMIRMLEDAGLTQGDVRTPQQVVSDMQWNTSAGPSYQGKKRDVCAHLSEQEVLHLAETSRQQFLACNSIGIWNGSLKAELRTIEKVEAEKTRVFTASPITSLFAMKFYVDDFNKKFYATNLRAPHTVGINKFSRGWEMLHDKLNRPGWLHGSGDGSRFDSSIDPFFFDIIKEIRKHFLPVEHHRAIDLIYDEILNTNICLANGMVIRKNVGNNSGQPSTVVDNTLVLMVSFLYAYIHKTGDHMLKKLNDRFVFVCNGDDNKFAISPEFDAEFGHDFSPELTELGLTYEFDDITDDICANPYMSLTMVRTPFGIGFSLPVERIVAIMQWAKKGGVLHSYLAGISAIYESFNTPKLFKSVYAYLLWLTEEHGSDILAAMTGTETALPIPSMLDVYRLHYGDSSIELQAADTQTDAQKEEARLAAATKKAADDADAARLRKVEADRVEAARVKKASDDKKARDLTATKVDDGKIVADAGTKRTNAATKEKWSLPETKPVNAGLKLRISMDKLKSAPKSIIEHDNSIALDSEVKKWSDAVRTSLGITTDEAWINALIPFLGWCANSGASDKHAENQTMQVDNGTGALTEMSLSPFIVHARLNGGLRRILRAYSDETVLLLQEHKIVTKWAMKHGASAHAAYAFDFFVPRPWMNPQDIEVAKQARLAALGTGTYNTMLTSDTTNLRKTTNRRVLDTDGHPELT
Protein: Probable G-protein coupled receptor Mth-like 5 (Protein methuselah-like 5) (Q9VGG8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable G-protein coupled receptor Mth-like 14
- LD28817p
Sequence:
MLVKTLGAHFAAGQNAKKCSCCALLISLLCVLLLSLNPLPVTSHVTSAGSSTALSSDPNLVLVNKCCEKFEIHVDHECQQVNETDYFQPMFTSYGGEQNRPVKFKFVIGIPNCGSMQMWPIYHYAGSSDKLVLLDDGRLRHYTNAENEAEERHGIQSDYEEDIAGSLEPLYHDYDKGLYCIDKATSSTGEENVLFANICLARKEIKWSDSNFLLRKILNPIFHGISLVILLVIAIIYFILPTLRDLVGNIVTTIAMCLMVSQAADLVRIFTELTSHVSFIVADIILCFSLLAAFFWLNSFGFYIWKTFRSRNVFLRVTDGRKYCYYSAYAWGCTATMAALAVFAHFFLDAESYKQEHMVGEQETIGWLGICIFFAPIACTILVNIFFYVTTRKLINRRTVYGRIAHKLKANFIMFSLMLLVMSIAWLFLIMSWLQMEGLLYAHIVVNALQTPLLLYICVLRQRHVTFLLKKTCCYNEPPSANDWGDELHYMNGNDY
Protein: Protein phosphatase (EC 3.1.3.16) (Q9W0E2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MHSSLSWTSRAISRALRSSFSTLLETATGGGSGAAAKGATKSGATPGSSGAPRPRFVSVVCGFAKDNLRHKYKPGKYGEDSWFKASTASADVMGVADGVGGWRSYGIDPGEFSSFLMRTCERLVQCSHFNPQRPVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVREGQVVHKSEEQQHYFNTPFQLSLPPPGHGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPEDLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGGKPDDITVVLATVAM
Protein: T-complex protein 1 subunit zeta 2 (TCP-1-zeta 2) (CCT-zeta 2) (Chaperonin CCT6B) (Q8L7N0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit eta
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit gamma
- TCP-1/cpn60 chaperonin family protein
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit theta
- ATP binding protein
- Nucleic acid-binding/zinc ion-binding protein
Sequence:
MSVRVLNPNAEVLNKSAALHMTINAAKGLQDVLKSNLGPKGTIKMLVGGSGDIKLTKDGNTLLKEMQIQNPTAIMIARTAVAQDDISGDGTTSTVIFIGELMKQSERCIDEGMHPRVLVDGFEIAKRATLQFLDNFKTPVVMGDEVDKEILKMVARTTLRTKLYEGLADQLTDIVVNSVLCIRKPEEAIDLFMVEIMHMRHKFDVDTRLVEGLVLDHGSRHPDMKRRAENCHILTCNVSLEYEKSEINAGFFYSNAEQREAMVTAERRSVDERVKKIIELKKKVCGDNDNFVVINQKGIDPPSLDLLAREGIIGLRRAKRRNMERLVLACGGEAVNSVDDLTPESLGWAGLVYEHVLGEEKYTFVEQVKNPNSCTILIKGPNDHTIAQIKDAVRDGLRSVKNTIEDECVVLGAGAFEVAARQHLLNEVKKTVQGRAQLGVEAFANALLVVPKTLAENAGLDTQDVIISLTSEHDKGNVVGLNLQDGEPIDPQLAGIFDNYSVKRQLINSGPVIASQLLLVDEVIRAGRNMRKPTA
Protein: FXYD domain-containing ion transport regulator 4 (P59646)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q63113}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63113}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q63113}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63113}. Note=Detected in the basolateral membrane of collecting duct principal cells. {ECO:0000250|UniProtKB:Q63113}.
Interaction partners:
- Gap junction delta-4 protein
- Sodium/potassium-transporting ATPase subunit gamma
- FXYD domain-containing ion transport regulator 7
- FXYD domain-containing ion transport regulator 5
Sequence:
MERVTLALLLLAGLTALEANDPFANKDDPFYYDWKNLQLSGLICGGLLAIAGIAAVLSGKCKCKSSQKQHSPVPEKAIPLITPGSATTC
Protein: 26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (Zgc:162272 protein) (A3KNN5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDRLLRLGGGMPGLSQGPPTDALAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKLNETIVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFH
Protein: Glucagon family neuropeptides [Cleaved into: Growth hormone-releasing factor 1-46 (GRF) (Growth hormone-releasing hormone) (GHRH); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)] (P41534)
Organism: Gallus gallus (Chicken)
Function: Primary role of GRF is to release GH from the pituitary.
Subcellular location: Secreted.
Interaction partners:
- ADCYAP receptor type I
- Vasoactive intestinal polypeptide receptor 2
- Secretin.
- Uncharacterized protein
- Secretin receptor
- Growth hormone-releasing hormone receptor
- Pro-neuropeptide Y
Sequence:
MSGNVYKTLLTLLVYGLIMHCNVYCSPDRWTPVPGAKLEEEVYDEDGNTLQDFALRAGAPGGGGPRPRWGRCTALYYPPGKRHADGIFSKAYRKLLGQLSARNYLHSLMAKRVGGASSGLGDEAEPLSKRHIDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRVAYL
Protein: Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIase A-like 4A) (EC 5.2.1.8) (Chromosome one-amplified sequence 2) (COAS-2) (Cyclophilin homolog overexpressed in liver cancer) (Q9Y536)
Organism: Homo sapiens (Human)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62937}.
Interaction partners:
- NBPF family member NBPF12
- Ran-specific GTPase-activating protein
Sequence:
MVNSVVFFDITVDGKPLGRISIKLFADKILKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
Protein: RRM domain-containing protein (D5MCQ5)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MNASSAPQQQQQQQQPQQGQAPQQQQQGPPQHQYQQQRPFHGRVQNHMRGSGPFGNSNGYGRYTAPRGDQQHHDSTPLSSVSSRRVPLPPTSQHRASSNFNTTPSSTNLYIRGLMPNTNDDLLREMCSKYGNIASTKAIMDKATNNCKGYGFVDFESPQAAAAAVDGLNTEGVQAQMAKLQQQEQDPTNLYIANLPLDFTEQMLETELNKFGMVISTRILRTPDNQSRGVGFARMDSKEKCEVIISALNGGRFDTMSKEGPALLIKQADTGRKSKVGSTSRHPSFQQFSSLGGPTAFLNGQHSMNNPEMLQRMQYPQVYQSYYGYHPAAVYQQHYDVNSLASQMGGMHVGGGNPQANGGGDMYGAHMYGQNAGGQGGQGVGQGGQVFPADESTINGQDNVFTPLLLSSLNLFSLSILSNQSSLQKKTQCAAARAAINTHVHIVSPLPDPQNLLLFLNPKTIVPF