wanglab/gogpt-training-data huggingface dataset:
Protein: Em-like protein GEA1 (EM1) (Q07187)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: It is thought to provide protection for the cytoplasm during the desiccation stage of embryo development.
Interaction partners:
- Protein ABSCISIC ACID-INSENSITIVE 5
- Low-temperature-induced 65 kDa protein
- B3 domain-containing transcription factor ABI3
- Ethylene-responsive transcription factor ABI4
- Serine/threonine-protein kinase SRK2D
- Serine/threonine-protein kinase SRK2I
Sequence:
MASKQLSREELDEKAKQGETVVPGGTGGHSLEAQEHLAEGRSKGGQTRKEQLGHEGYQEIGHKGGEARKEQLGHEGYQEMGHKGGEARKEQLGHEGYQEMGHKGGEARKEQLGHEGYKEMGRKGGLSTMEKSGGERAEEEGIEIDESKFTNK
Protein: Conserved protein (O50442)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- proline dehydrogenase
- L-glutamate gamma-semialdehyde dehydrogenase
Sequence:
MRIAGVGLGQLLLALDATVVSLVDAPRGLDLPVASTALIDSDDVRLGLAAAAGSADVFFLIGVTDDEAVRWVDDQARQRAPVAIFVKHPSDSVVAGAVRAGSAVVAVEPRARWERLYHLVNHVLEHHGDRADPTDDSGTDLFGLAQSLADRIHGMISIEDAQSHVLAYSASNDEADELRRLSILGRAGPPEHLQWIGQWGIFDALRPGREVVRVAERPELGLRPRLAIGIHQPGVGALRPPVFAGTIWVQQGSQPLADDAEEMLRGAAVLAARIMSRLATQPNTHALRVQQLLGLAELNATTAPVDVSTIARELGVAAEGNATLIGFDTAENRDTAVRHVRLVDVMALSASAFRHDAQVAANGSRIYVLLPQTTTGRAVTSWVRGTISALRAELGVALRAAIAGPVAGLAEVNPARVEVDRVLESAERHPILGQVTSLAEARTTVLLDEIVTLVGTDQRLVDPRIRDLGAQDPVLAQTLRAYLDAFGDIGAAARSLQVHPNTVRYRIRRIEQLLSTSLGDPDVRLLFSLGLRAMERTA
Protein: TIR domain-containing protein (Q5ZJ34)
Organism: Gallus gallus (Chicken)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MMETAEKAWPSTRMCPSHCCPLWLLLLVTVTLMPMVHPYGFRNCIEDVKAPLYFRCIQRFLQSPALAVSDLPPHAIALNLSYNKMRCLQPSAFAHLTQLHTLDLTYNLLETLSPGAFNGLGVLVVLDLSHNKLTTLAEGVFNSLGNLSSLQVQHNPLSTVSPSALLPLVNLRRLSLRGGRLNGLGAVAVAVQGLAQLELLDLCENNLTTLGPGPPLPASLLTLQLCNNSLRELAGGSPEMLWHVKILDLSYNSISQAEVFTQLHLRNISLLHLIGNPLDVFHLLDISDIQPRSLDFSGLVLGAQGLDKVCLRLQGPQALRRLQLQRNGLKVLHCNALQLCPVLRELDLSWNRLQHVGCAGRLLGKKQREKLEVLTVEHNLLKKLPSCLGAQVLPRLYNVSFRFNRILTVGPQAFAYAPALQVLWLNINSLVWLDRQALWRLHNLTELRLDNNLLTDLYHNSFIDLHRLRTLNLRNNRVSVLFSGVFQGLAELQTLDLGGNNLRHLTAQSLQGLPKLRRLYLDRNRLLEVSSTVFAPVQATLGVLDLRANNLQYISQWLRKPPPFRNLSSLYDLKLQAQQPYGLKMLPHYFFQGLVRLQQLSLSQNMLRSIPPDVFEDLGQLRSLALADSSNGLHDLPDGIFRNLGNLRFLDLENAGLHSLTLEVFGNLSRLQVLHLARNELKTFNDSVASRLSSLRYLDLRKCPLSCTCDNMWLQGWLNNSRVQVVYPYNYTCGSQHNAYIHSFDTHVCFLDLGLYLFAGTAPAVLLLLVVPVVYHRAYWRLKYHWYLLRCWVNQRWRREEKCYLYDSFVSYNSADESWVLQKLVPELEHGAFRLCLHHRDFQPGRSIIDNIVDAVYNSRKTVCVVSRSYLRSEWCSLEVQLASYRLLDERRDILVLVLLEDVGDAELSAYHRMRRVLLRRTYLRWPLDPAAQPLFWARLKRALRWGEGGEEEEEEGLGGGTGRPREGDKQM
Protein: Protein OPG107 (P08583)
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Function: Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation).
Subcellular location: Virion membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. Host endoplasmic reticulum membrane {ECO:0000269|PubMed:18417576}. Note=Component of the mature virion (MV) membrane (By similarity). The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis. {ECO:0000250}.
Interaction partners:
Sequence:
MDKTTLSVNACNLEYVREKAIVGVQAAKTSTLIFFVIILAISALLLWFQTSDNPVFNELTRYMRIKNTVNDWKSLTDSKTKLESDRGRLLAAGKDDIFEFKCVDFGAYFIAMRLDKKTYLPQAIRRGTGDAWMVKKAAKVDPSAQQFCQYLIKHKSNNVITCGNEMLNELGYSGYFMSPHWCSDFSNME
Protein: Calcium and integrin-binding family member 2 (Q6PC72)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9Z309}. Cell projection, stereocilium {ECO:0000250|UniProtKB:O75838}. Photoreceptor inner segment {ECO:0000250|UniProtKB:Q9Z309}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q9Z309}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q9Z309}.
Interaction partners:
- Transmembrane channel-like protein 1
- Usher syndrome 1Gb
- PDZ domain-containing 7a.
- Cadherin-related 23.
- Myosin VIIAa
- Harmonin
- Clarin 1
- Protocadherin-15
- Usher syndrome 2A
- Whirlin
Sequence:
MGNKQTIFTDEQLDAYQDCTFFTRKEILRLHGRYHELAPHLVPMDYTNDPDVKVPLALIVNMPELKENPFRNRIVESFSEDGQGNLSFNDFVDMFSVLSEMAPRELKAIYAFKIYDFNVDNYICKEDLEKTLNKLTKEELTPEEVNLVCEKAIEEADLDGDNKLSFADFENMISRAPDFLSTFHIRI
Protein: TATA element modulatory factor 1 (A0A2R8Y7M0)
Organism: Homo sapiens (Human)
Subcellular location: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
Sequence:
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEETVNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQSLS
Protein: Heterochromatin protein 5, isoform C (M9PHL2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDIFDMVKAAPPPQTINPVDTKLSTPSPIPPDSPIDVNDLLESGNQLDENDLRMSRKSKNVEQCSIDLFDSETSFDHLDESLAKRKRKSVANSKPNKSRKSTVSASTPHNKRPKVSIDDDGEAIEEDQQSMVVVPTKTKAQQKMFSDQQSPNVKRKVRVLLRRLKQTEIDSAVESLANSSFINVPEIVNQSGTSGRSRHKKRKTSPKKQKSSTAQTNFHIKVPLQNGAKKRALNHSLRAHTPPPSLAKSSESTHSALKRSPKPKIKAKRLSSRGRNTDPDLVKRYGAHFFGCVVKVRRTRLPSAKWPDCKPPPIGDGVVRKVYPKKAVSFSEAVEILGSPGGPSRRSTFGSLSSRGAPKPTRLQRVDATGNVLEDIALTSTPLFSSSSGGSRERVRRRSCNGTPVVGRLKLRRLGRLSIDNSSSRSDGGGDNDDDDEEYIGFDQIKLKKN
Protein: Transmembrane 4 L six family member 4 (Transmembrane 4 L6 family member 4) (Zgc:92479) (Q6DBQ4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MCSGNFAKCLGITLIPLAIICVLCNILLFFPSGKVADQSQDITDEVFYLGGILGSGVLMIFPALVFLGLKNNDCCGCCGNESCGKRFAMFSSILFAAAGAVGAGYSVIVSCVALNHGPKCFLSDGSNNATYPFTDGNYLSNRTMWELCAGPGDIVTWHLTLFSILLITGIVQIGLCAFQVINGLIGTICGDCCGCCKE
Protein: Isocitrate dehydrogenase kinase/phosphatase (IDH kinase/phosphatase) (IDHK/P) (EC 2.7.11.5) (EC 3.1.3.-) (P11071)
Organism: Escherichia coli (strain K12)
Function: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
Subcellular location: Cytoplasm.
Interaction partners:
- Isocitrate lyase
- Isocitrate dehydrogenase
- Malate synthase A
- Transcriptional repressor IclR
- Malate synthase G
- Glyoxylate/hydroxypyruvate reductase A
Sequence:
MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
Protein: Ladinin-1 (Lad-1) (E9PDI4)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|PIRNR:PIRNR038144}.
Interaction partners:
Sequence:
MRLCLGRPHPRGHSRVGKSERGRGARGLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRKENLRLSGVVTSRLNLWISRTQESGDQDPQEAQKASSATERTQWGQKSDSSLDAEV
Protein: Autophagy-related protein 2 (Q2XXT6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004406}. Preautophagosomal structure membrane {ECO:0000256|ARBA:ARBA00004623}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004623}.
Interaction partners:
Sequence:
QRYLGQFFENNLNLEQLKVDLYNGKAVVEDIFLKVNAFNDLFEDQGWAFEVVSGHIGRLTVVVPWNALMTNDSSLEIHNLTITLRPVTRYQSGTTMLESMWSSVSSSMQMAEECMKQVDDDVPFLNHNNALIGLEKFAETIDNVLNRIRAKLTNTTLNIEYILPRSDRKLVLSFQASHVEYKNKTGYEMPMSTSQDTETEEDPNSSFNALPMIAKHNLVIEGLSLHTSEVLDVMDHQFGPTPYEQLCKIVELKGAQNIQINIKQTENIVGPKVSLELSLDDIYFMLTPRQIHLLIEFSKGFNCGGQQERPKKGRSLKSAPPSEYQMHSLQQPTRMTGILGQNADWCTGMSEADPSEYSAYGNPPRSGYARSRKMSESTNSMVTSCTNTLQQELGYTEKSGEILKFKVQISKIYGIALHQDILIQNTANIDSCSTVFDHASYLRYSDTASGFFLGTLLENHIPLQNQQYLLLRAAPIIVSGSQQRYFQELTSRTTLSATAVDLIEVLDNSKEHLLQFDRQRNCPDGYHIRPEIVLTQSSSFMFKQNHNRCSNKIECSLDECTAELDISIYDRLGALFGSSPFSADSASSTPYPDDPNQTEFVVKSENLRLHLRFPVVDGRAANDPLKIPWWKKNVRRDFLAVEFRSLVVSSRSQISIVSDELDVFYCDADKQSAVHLLKCQQRMQPNKKIQIDVLQLKDTSDGQKKARKSPFSSKCTFGYTSHVEGLDGSVDKTDSLLPGETEEINEFCDSCTQSSKLKIFTFIPHVKVVLESKSMYELIYNRLNGDLFMWEPRSPHYDINLDNEVPESKDLYAEPQLEEFRRNLLLSTSAMESSIYFSMAEPTVSAPPVPPVRNEAFSFELFVEQGTLILFSHLLDPETNQRSKECGKFQVNLKELRLFTVNGLDNDSTRSFFSIQLGEIDALHCGNTLQDLELAWSDLEDAKLLPTIYNFANVHQQQDRKRMEVLSLVAEIKKQPEQRIKRMKMSFGICGAILQHHSCHSEHSWLNQLIDFMDVADFPIEEYEPFALVSELQLHVWNAGIDYRPKFFPQRAFLDLGYCTLSSNIISSMSGCTLRLLAEDCVLQLGLVKEESNDSLIPVLNLGLLNISFRLNAEGSGQPRVDLRSSIHDMHLKTCYDSATALAQLIAYVANDRDLCPPEEPILNEDTKPAEPKPNEEHEVSDHTQNHVSKLMADAVIDVESSPNLRAMKSPGGREEGIEIFYFPDEPKEKRKSTSAKLQTKSLMVESPSVIGDILDFESNVILQSYYHQSQVQPQTSLGSQVQQELGSLGNASLEERDFDIIHDEEISRMDKFGVKQIYISEDPLQIVDNHFELPHEKVDLLRPPSNFPVAESTYTLCEMTFTWHLYGGRDFPDEPLKKSSSSATSGFGMSDTYKYGVSQAQEQDKQDKKGSKKGLLKQPKGSQRNLEVLVEMQLSKIRFSYETYPLTSMYSSRQVLLVSEIEIRDRLRSSDINKFLYHPTGNNLSHKPDENMVIVKALNVRPNPQKSSAEECSLRVSILPIKLNIDQDTLLFLEDFFSGMFRNSASAAGGTKTEGSSSSATDMPVMSVSKMPEELSDELPDSEVKEMVERNLNVLIEENSLDVELEEDPATAPPVFFREVIFSPALPICFDYHGRRIELSRGPVTGLIMGLAQLQGSGINLREIVNRRGILGWNKLCEFLAKEWLKDIKRNQLPNILSGIGPTNAVLQLFQGIYDLFRLPIEQYNKDGRIIRGFQLGAQSFTARTALAALEITSRIIHLLQFTAETTFDMLSAGPSMKKRKGGRQGKRRRQGRPKDLREGVANAYTIVREGINESANTLIEAAITEHDQKGYSGAVGAVVRQIPQLVVCPAVLATQATTNILGGAKSSLIPE
Protein: Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein homolog) (Nucleoporin-like protein RIP) (Q8K2K6)
Organism: Mus musculus (Mouse)
Function: Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P52594}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P52594}. Note=Associated with the cytosolic surface of proacrosomic vesicles of early round spermatids. {ECO:0000269|PubMed:11711676}.
Interaction partners:
- Vesicle-associated membrane protein 7
Sequence:
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGESAPALHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSSFQPQTTGGSAGSVNANFAHFDNFPKSSSADFGTFSTSQSHQTASTVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSHSSASSDKYAALAELDSVFSSAATSSNAYTPTSNASSSVFGTVPVGASAQTQPASSGPAPFGATPSTNPFVAATGPSAASSTNPFQTNARGATAATFGTASMSMPAGFGTPAQYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFATFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQLPTGSSSTNPFL
Protein: Bowman-Birk type proteinase inhibitor 4 (LSI-4) (B3EWN8)
Organism: Lathyrus sativus (White vetchling)
Function: Inhibits trypsin (IC(50)=17.60 nM) and, to a lesser extent, alpha-chymotrypsin (IC(50)=2.38 uM).
Interaction partners:
Sequence:
GDDVKSACCDTCLCTKSNPPICRCVDIRET
Protein: BTB/POZ and MATH domain-containing protein 5 (Protein BTB-POZ AND MATH DOMAIN 5) (AtBPM5) (Q1EBV6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular location: Nucleus {ECO:0000269|PubMed:19843165}. Cytoplasm {ECO:0000269|PubMed:19843165}.
Interaction partners:
- Cullin-3B
- Cullin-3A
- PEARLI 4 protein family protein)
- E3 ubiquitin-protein ligase RGLG1
Sequence:
MSESVIQGSNPDRVLSPTSSKSVTQTVNGSHQFVIQGYSLAKGMGIGKHIASDNFSVGGYQWGIFFYPDGKNPEDNSSYVSVFIALASEGTEVRALFELALVDQSGKGKHKVHSHFERSLDGGPYTLKYRGSMWGYKRFFRRSILETSDYLKDDCLIINCTVGVVVSEILCPQLHSVHVPDSELGSHFGVLLDSMEGSDITFNIAGEKFLAHKLVLAARSPFFKSKFFSEFEANNTEVTINDLEPKVFKALLQFMYKDSLPEDVEPATAHTFERLKLSEIYETLIVKVLAAADKYDLIRLRLLCESHICKGVSVKSVAKILALADRYNAKELKGVCLKFTAENLAAVLETDAYQQMKDECVTLQSELLKAVAGHEEGSNSTGGAKSQSVWAQLSDGGGDTTSRHVRQRTT
Protein: KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog) (H0YHR2)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
ENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQDLDVVGDGMQCPPSPLLFDPSLTLEDHLVKEIAEDPVDILGQMQMAGDGCRSQGSRNSEKASAPLSQSGLATANGKPEPTSIS
Protein: Transcriptional regulatory protein CusR (P0ACZ8)
Organism: Escherichia coli (strain K12)
Function: Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Activates the expression of cusCFBA, hiuH and plasmid pRJ1004 gene pcoE in response to increasing levels of copper or silver ions. Can also increase the basal-level expression of copper resistance gene operon pcoABCD.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Sensor histidine kinase CusS
- Cation efflux system protein CusC
- Cation efflux system protein CusB
- Cation efflux system protein CusF
- Cation efflux system protein CusA
- Sensor histidine kinase HprS
- HTH-type transcriptional regulator CueR
- Multicopper oxidase CueO
- Sensor histidine kinase CpxA
- Sensor protein BasS
Sequence:
MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLEFFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ
Protein: LD03740p (Q8T0H3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
Interaction partners:
Sequence:
MRWRDPNLSEVISFLSNPSSAIKANAAAYLQHLCYMDDPNKQRTRSLGGIPPLVRLLSYDSPEIHKNACGALRNLSYGRQNDENKRGIKNAGGIAALVHLLCRSQETEVKELVTGVLWNMSSCEDLKRSIIDEALVAVVCSVIKPHSGWDAVCCGETCFSTVFRNASGVLRNVSSAGEHARGCLRNCEHLVECLLYVVRTSIEKNNIGNKTVENCVCILRNLSYRCQEVDDPNYDKHPFITPERVIPSSSKGENLGCFGTNKKKKEANNSDALNEYNISADYSKSSVTYNKLNKGYEQLWQPEVVQYYLSLLQSCSNPETLEAAAGAIQNLSACYWQPSIDIRATVRKEKGLPILVELLRMEVDRVVCAVATALRNLAIDQRNKELIGKYAMRDLVQKLPSGNVQHDQNTSDDTITAVLATINEVIKKNPEFSRSLLDSGGIDRLMNITKRKEKYTSCVLKFASQVLYTMWQHNELRDVYKKNGWKEQDFVSKHFTAHNTPPSSPNNVNNTLNRPMASQGRTRYEDRTIQRGTSTLYSANDSSGAVMSNESAMLSEMVRKQL
Protein: (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase (EC 5.3.1.32) (Autoinducer 2-degrading protein LsrG) (AI-2-degrading protein LsrG) (Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase) (Phospho-AI-2 isomerase) (P64461)
Organism: Escherichia coli (strain K12)
Function: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02051}.
Interaction partners:
- 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase
- Autoinducer 2-binding protein LsrB
- Autoinducer 2 import system permease protein LsrD
- Autoinducer-2 kinase
- Autoinducer 2 import system permease protein LsrC
- Autoinducer 2 import ATP-binding protein LsrA
- Transcriptional regulator LsrR
- Trans-aconitate 2-methyltransferase
- S-ribosylhomocysteine lyase
Sequence:
MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDPEVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP
Protein: Electon transport protein SCO1/SCO2, putative (Q38FS2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cytochrome oxidase assembly protein, putative
Sequence:
MMRRHSTGGTGGGKDIDVVDKEKPIHIRVAEQRDSQIFTFQEYVEREEEAERRKLSERLSEVRDSPAWMLWGLLFLSLGVITVVISIRVRREQMRFDPKLRAVKAFDSPEGPSIGGPFSLIGVDGRRYTEKDFLGKWLYIYFGFTNCPDVCPEEMAKLSRVVQHLDKKVGRDYWQPIFISLDPHRDTPEKIRDYLADFNPRILGLVGTQEEVESVARQYRVYFALPDETVLSEDDYLVDHSIIMYLMNPEGKFCDYTTKEFQWFESYSKLLRRMMDYERDKVIQRREAGASDDNGQAAINIKVANVATMLDENVASVQKPSEI
Protein: LD43276p (Q8SX58)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMARALQECPNAGELWAEAIFMETKPQRKTKSVDALKKCEHDPHVLLAVSKLFWSEHKFSKCRDWFNRTVKIDPDLGDAWAYFYKFELLHGTEAQQQEVLDRCISAEPTHGESWCRVSKNIQNWQFKTPEVLRAVVRELSIPI
Protein: Photosystem II lipoprotein Psb27 (Photosystem II 11 kDa protein) (P74367)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Plays a role in the repair and/or biogenesis of the calcium-manganese-oxide cluster on the lumenal face of the thylakoid membrane. Photosystem II (PSII) complexes containing this protein are monomeric, are assembly intermediates lacking the calcium-manganese-oxide cluster and miss some of the lumenal subunits. Probably blocks binding of some of the small lumenal subunits.
Subcellular location: Cellular thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01481, ECO:0000269|PubMed:15308630, ECO:0000269|PubMed:21592967, ECO:0000269|PubMed:22086423}; Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_01481, ECO:0000269|PubMed:15308630, ECO:0000269|PubMed:21592967, ECO:0000269|PubMed:22086423}; Lumenal side {ECO:0000255|HAMAP-Rule:MF_01481, ECO:0000269|PubMed:15308630, ECO:0000269|PubMed:21592967, ECO:0000269|PubMed:22086423}. Note=Associated with PSII on the lumenal side of the thylakoid membrane.
Interaction partners:
- Photosystem II reaction center Psb28 protein
- Photosystem II extrinsic protein U
- Photosystem II extrinsic protein V
- Photosystem II extrinsic protein O
- Photosystem II CP47 reaction center protein
- Photosystem II CP43 reaction center protein
- Iron stress-induced chlorophyll-binding protein
- Photosystem II reaction center protein M
- Cytochrome b559 subunit alpha
- Photosystem II reaction center protein X
Sequence:
MSFLKNQLSRLLALILVVAIGLTACDSGTGLTGNYSQDTLTVIATLREAIDLPQDAPNRQEVQDTARGQINDYISRYRRKGDAGGLKSFTTMQTALNSLAGYYTSYGARPIPEKLKKRLQLEFTQAERSIERGV
Protein: Cuticular protein 49Ac, isoform C (LP08773p) (Q7JR69)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFTKSMLSFSLVVALFVVCHASPVPDNNGKYTVPQQSSNDGKYRPSDDGKYHGNSQNEGRSGSQESIGRYHHMPIPYRHVSDQRELGKYHHIPYPYDGGYGPYAGSNIPYVHDDRPYNHDLYTSTTTKKPTTTTKRTTTSTTTTTTTPRNILFNYDDEGRHKILHKEEVRKQDKYDHSYLTENGIYGEEQAKLHHTGGTHAKGFYEYTGDDGKLYRVNYASNDGGFMPQGDHIHPIPDAIVRALKYVEEQHKINGGAQFDHRGFRINHMTKDLKAQIKAIHLEEMPKELTEQIHMLEHEVELAEEEEREEQAALERLRQAAKSH
Protein: Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6) (Q91Z92)
Organism: Mus musculus (Mouse)
Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q96L58}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q96L58}.
Interaction partners:
- Beta-1,4-galactosyltransferase 7
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
- Ubiquitin-conjugating enzyme E2 J2
- Xylosyltransferase 1
- Xylosyltransferase 2
- Exostosin-like 2
- Glycosaminoglycan xylosylkinase
Sequence:
MKVFRRAWRHRVALGLGGLAFCGTTLLYLARCASEGETPSASGAARPRAKAFLAVLVASAPRAVERRTAVRSTWLAPERRGGPEDVWARFAVGTGGLGSEERRALELEQAQHGDLLLLPALRDAYENLTAKVLAMLTWLDERVDFEFVLKADDDSFARLDAILVDLRAREPARRRRLYWGFFSGRGRVKPGGRWREAAWQLCDYYLPYALGGGYVLSADLVHYLRLSREYLRAWHSEDVSLGTWLAPVDVQREHDPRFDTEYKSRGCNNQYLVTHKQSPEDMLEKQQMLLHEGRLCKHEVQLRLSYVYDWSAPPSQCCQRKEGVP
Protein: Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) (P13596)
Organism: Rattus norvegicus (Rat)
Function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Major prion protein
- GDNF family receptor alpha-1
- Neurocan core protein
- Neural cell adhesion molecule L1
- Low affinity immunoglobulin gamma Fc region receptor III
- CD19 molecule
- Cadherin-2
- Neural cell adhesion molecule 2
- Tyrosine-protein kinase Fyn
- Neuromodulin
Sequence:
MLRTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNGKGLGEISAATEFKTQPVREPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVETKSEPQESEAKPAPTEVKTVPNEATQTKENESKA
Protein: Organelle RRM domain-containing protein 6, chloroplastic (Q9FX45)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in C-to-U editing of chloroplastic RNA. Required for the photosynthetic subunit psbF transcript editing in chloroplast.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:28213559}.
Interaction partners:
- Uncharacterized protein T9L24.31
- 2-thiocytidine tRNA biosynthesis protein, TtcA
- Multiple organellar RNA editing factor 2, chloroplastic
- Multiple organellar RNA editing factor 9, chloroplastic
- RNA-binding protein CP31B
- Multiple organellar RNA editing factor 8, chloroplastic/mitochondrial
- Small ribosomal subunit protein eS12z
- Protoporphyrinogen oxidase 1, chloroplastic
- Zinc finger protein VAR3, chloroplastic
- 31 kDa ribonucleoprotein, chloroplastic
Sequence:
MAISLGRVVVPSCTISGDRLFIPNFSAICSVSCGRINVGTGVISARRRRDIGGVLISSCLSTDSSSSPPSSSSGPKTKLYVSGLSFRTTEDTLRDTFEQFGNLIHMNMVMDKVANRPKGFAFLRYETEEEAMKAIQGMHGKFLDGRVIFVEEAKTRSDMSRAKPRRDFPKPQSKPRTFRTW
Protein: FT-like protein (Hd3a) (Q93WM7)
Organism: Oryza sativa subsp. indica (Rice)
Interaction partners:
Sequence:
MAGSGRDRDPLVVGRVVGDVLDAFVRSTNLKVTYGSKTVSNGCELKPSMVTHQPRVEVGGNDMRTFYTLVMVDPDAPSPSDPNLREYLHWLVTDIPGTTAASFGQEVMCYESPRPTMGIHRLVFVLFQQLGRQTVYAPGWRQNFNTKDFAELYNLGSPVAAVYFNCQREAGSGGRRVYN