wanglab/gogpt-training-data huggingface dataset:
Protein: [F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (ERK2-binding testicular protein 1) (MICAL C-terminal-like protein) (Mical-cL) (Molecule interacting with CasL protein 2) (MICAL-2) (mMical2) (Q8BML1)
Organism: Mus musculus (Mouse)
Function: Methionine monooxygenase that promotes depolymerization of F-actin by mediating oxidation of residues 'Met-44' and 'Met-47' on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. Regulates the disassembly of branched actin networks also by oxidizing ARP3B-containing ARP2/3 complexes leading to ARP3B dissociation from the network. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18241670}. Nucleus {ECO:0000250|UniProtKB:O94851}.
Interaction partners:
- Enhancer of filamentation 1
- Ras-related protein Rab-8A
Sequence:
MGENEDEKQAQASQVFENFVQATTCKGTLQAFNILTCLLDLDPLDHRNFYSQLKSKVNTWKAKALWHKLDKRGSHKEYKRGKACSNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDTFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEVHVNVEFVRVLEPPEDQENQKVGWRAEFLPADHALSDFEFDVIIGADGHRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDSTHYFVMTAKKQSLLDKGVILNDYIDTEMLLCSENVNQDNLLSYAREAADFATNYQLPSLDFAINHNGQPDVAMFDFTSMYASENAALMRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWDQGTPPLEVLAERESLYRLLPQTTPENINKNFEQYTLDPATRYPNLNLHCVRPHQVKHLYITKEMDRFPLERWGSVRRSVSLSRRESDIRPNKLLTWCQQQTKGYQHVRVTDLTTSWRSGLALCAIIHSFRPELINFDSLNEDDAVENNQLAFDVAKREFGILPVTTGKEMASTQEPDKLSMVMYLSKFYELFRGTPLRPMDSWRKNYGENADFGLGKTFIQNNYLNLTLPRKRTPRVDTQTEENDMNKRRRQGFNHLEELPSFSSRSLGSSQEYAKESGSQNKVKHMANQLLAKFEENTRNPSVVKQDCRRVSGIGKPVLCSASRPPGTSCCPKLEESTPRLPPPLKRQFSSTVATGQVLRELNQVPASGECPSRPWRARAKSDLQLGGVENLATLPRTCQGALALSGVLRRLQQVEEKVLQKRAQNLANREFHTKNIKEKAAHLASMFGHGDLPQDKLLSKRVPHAHPPSPPSCLPSPHPAAASSPPAADSVSPARKVVALNHRLPPPLHLTVGKVSSGIGAAAEVLVNLYLNDHRPKTQATSPDLESPRKAFPLSLGGRDTCYFCKKRVYMIERLSAEGHFFHQECFRCSVCSATLRLAAYAFDCDEGKFYCKPHFVHCKTSSKQRKRRAELNQQREEEGTWQEQEAPRRDVPTESSCAVAAISTPEGSPPDEPISPKKPKSVPEPNPRDVEAEATSPRPSEWTSVRISPGEDTVRQDVLAVRVLVTSEDSSSDTESDYGSITAPCAGAYEERPQLPESPPLSKPLTRHISLRENLTQPVSLLHEEPQALPALQRAHSLQSPTPSKYQNWRRRFQSNSTPMNQRAPSPPKEPPPPPSLSSSSSLPSSFSSASVPGHTADDSSSPQVTYNLHSPQISRGDVSPTPIYLRRARAQGIVKEIPLYLPHSPMLESTEDCLVEPGRESLRSPEEISSSEGCQEARALGNTRSIQHPILGKDQYLPNQNLALGAAGNPGDPREESRMGQPGGPELSKERKLGLKKLVLTEEQKNKLLDWSDCTQEHKTGEQLSQESAENIRGGSLKPTCSSTLSQAVKEKLLSQKKALGGMRTPAVKAPQEREVPPPKSPLKLIANAILRSLLHNSEAGKKTSPKPESKTLPRGQPHARSFSLRKLGSSKDGDQQSPGRHMAKKASAFFSLASPTSKVAQASDLSLPNSILRSRSLPSRPSKMFFSTTPHSKVEDVPTLLEKVSLQDATHSPKTGASHISSLGLKDKSFESFLQECKQRKDIGDFFNSPKEEGPPGNRVPSLEKLVQPVGSTSMGQVAHPSSTGQDARKLEGGEGGSSLVSSLVLVSDPVAPVTEATSSPTSSSAEEEADSQLSLRIKEKILRRRRKLEKQSAKQEELKRLHKAQAIQRQLEEVEERQRTLAIQGVKLEKVLRGEAADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLRQKMLKDEGQKDENDLKEEQEIFEEMMQVIEQRNKLVDSLEEQRVKERTQDQHFENFVLSRGCQLSRT
Protein: Probable succinate transporter subunit YjjB (P0ADD2)
Organism: Escherichia coli (strain K12)
Function: Involved in succinate export with YjjP. Both proteins are required for export. Contributes to succinate production under both aerobic and anaerobic conditions.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01191, ECO:0000305}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01191}.
Interaction partners:
- Probable succinate transporter subunit YjjP
- Uncharacterized protein YjjA
- Anaerobic C4-dicarboxylate transporter DcuC
- Replication restart protein DnaT
Sequence:
MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGSIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
Protein: histone acetyltransferase (EC 2.3.1.48) (E9PJI1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
Protein: Cystatin (Egg-white cystatin) (Ovocystatin) (P01038)
Organism: Gallus gallus (Chicken)
Function: This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum.
Subcellular location: Secreted.
Interaction partners:
- Uncharacterized protein
- Cathepsin B
- Procathepsin L
- Legumain.
- Uncharacterized protein
- Cystatin B
- Ovomucoid
- Uncharacterized protein
- Uncharacterized protein.
- Ovostatin
Sequence:
MAGARGCVVLLAAALMLVGAVLGSEDRSRLLGAPVPVDENDEGLQRALQFAMAEYNRASNDKYSSRVVRVISAKRQLVSGIKYILQVEIGRTTCPKSSGDLQSCEFHDEPEMAKYTTCTFVVYSIPWLNQIKLLESKCQ
Protein: Kre5p (A0A1D8PJN6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
- Calnexin
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3
- Beta-glucan synthesis-associated protein
- Glucosidase II subunit alpha
- Protein BIG1
- GDP-Man:Man
- GDP-mannose transporter
- Kre9p
- Skn1p
- Mannosyl-oligosaccharide glucosidase
Sequence:
MSIARYIYYTIAVAVLLNFVKATENNNFKLELEASWSNIDFLPSFIEAIVGFNDSLYEQTIETIFGLGDTEVELEDDASDQEIYSTVINSLRLTDQDLDFINFDLTNKKHTPRIAAHYDHYSDVLTKFGDRLKSECAKDSFGNAVETKNGQIQTWLLYNDKIYCSANDLFALRTDLSSHSTLLFDRIIGKSKDAPLVILYGNPTEESTKDFLKILYPDAKAGKLKFVWRYIPSGIKKSDSISGYGVSLKMEKYDYSGAEGNTKYDLSRDFTRINDSQELVLVIGKHSYELGVKLTSFILSNRYKTTKYDLLDTILTNFPKFIPYIARLPKLLNHEKVKSKVLGNEDIGLSQDSYGIYINGSPINPLELDIYNLGTRIKEELQTVKDLVKLGFDTVQAKLLIAKFALLSAVKQTQFRNGNTLMGNNENRFKVYENEFKKGSSEKGGVLFFNNIESDNTFKEYTTDREEAYLGVGSHKLKPNQIPLLKENIHDLIFALNFGNKNQLRVFFTLSKVILDSGIPQQVGVLPVIGDDPMDSLLAEKFYWIAEKSSTQEALAILYKYFESNSPDEVDDLLDKVEVPEDYKVDYNHVLNKFSISTASVIFNGVIYDLRAPNWQIAMSKQISQDISLIKTFLRQGPIEGRLKDVLYSNAKSERNLRIIPLEPSDIIYKKIDKELINNSIAFKKLDKAQGVSGTFWLVSDFTKSEIITQLIDLLLLLKKKAIQIRIINTGDTDVFGKLKTKFKLTALTNGQIDEIIEILKKSNASSANNDELKKMLETKQLPAHHSFLLFNSRYFRLDGNFGYEELDQIIEFEVSQRLNLIPDIMEAYPDEFRSKKVSDFNSVLSGLDNMDWFDLVTSIVTKSFHVDEKRFIVDVNRFDFSSLDFSNSIDVTTYEENSPVDVLIILNPMDEYSQKLISLVNSITDFSFLNIRILLQPRVDSKEEIKIHKFYRGVYPQPTPKFDSNGKWIQHYSAQFESIPSNVTYSTELDVPHKWIVVPQSSSMDLNTINFSESHSVDAKYSLKNILIEGYARDIHTGKAPDGLIFRAFNKNYSTDTLVMTSLDYFQIKGYPSIFNFSTTSNDTLLSASENKYQANTEELESIEVPVFKIDGSTIYPRVMKSGNNKPMSTRKHADINIFTIAGGQLYEKLTSIMIASVRKHNPSSTIKFWILEDFATPQFKHLVELISVKYNVEYEFISYKWPNFLRKQKTKERMIWGYKILFLDVLFPQDLNKIIFIDADQICRADLTELVNMDLEGAPYGFTPMCDSREEMEGFRFWKEGYWSDVLKDDLKYHISALFVVDLQKFRSIKAGDRLRAHYQKLSSDPNSLSNLDQDLPNNMQRSIKIFSLPQNWLWCETWCSDKSLEDAKMIDLCNNPLTRENKLDAAKRLIPEWIEYEQAIEPLVSLVQNNTAKEVVQEIEIDTDGEQEEQEQESNDDDFIHDEL
Protein: Transcription factor GATA-3 (GATA-binding factor 3) (Q91428)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus.
Interaction partners:
- Forkhead box A1
- Runt-related transcription factor
- T-box 21 like
- T-cell acute lymphocytic leukemia protein 1 homolog
- Ubiquitin carboxyl-terminal hydrolase
- Rhombotin-2
- Rhombotin-1
- E1A-binding protein p300 b.
- Interleukin 13
- Nuclear receptor-interacting protein 1
Sequence:
MEVSPEQHRWVTHHTVGQHPETHHPGLGHSYMDPSQYQLAEDVDVLFNIDGQSNHPYYGNPVRAVQRYPPPPHSSQMCRPSLLHGSLPWLDGGKSIGPHHSTSPWNLGPFPKTSLHHSSPGPLSVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPAISTSGSGSSVRQEDKECIKYQVSLAESMKLDSAHSRSMASIGAGASSAHHPIATYPSYVPDYGPGLFPPSSLIGGSSSSYGSKTRPKTRSSSEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKSHDSMEDFSKSLMEKNSSFSPAALSRHMTSFPPFSHSGHMLTTPTPMHPSSSLPFASHHPSSMVTAMG
Protein: Uncharacterized protein, isoform C (A0A0B4KEI8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MALNKRKSPYSDPISGAEVDYKLSCRCCLKTNVEYVKLDSVSVARSLDPADATEKIPLLRCLLFCVSADNAPELPQHICLECSKSLQVAYYFLQNALRAHEILCRKLCPKVSKRLNGTLAQEQEKPACAEPVQPLKTMRHECQVCGVVLYNRLELKQHIRQHAEGLSYNCKLCSFTSLKQRTLFEHYVTMHNMPLSQAEEYVKSKHLPAPKEEEVKAVCTLEDMELLIPTVLRPEDYVQPHPHIDNDQLRDIDHQLAVSMDEPVPSVDSLTSTLPPMDTPNVSIGTEYLVLPDGSLQQVNGSGVVIEYIDDSKPNSSSNVNVSLQNLLSSHNDPMDIDVNELIVEEMMPQIRNLPKFFCDQCDFYSLRSADLIQHYKMVHHRVDENGKTGKEQAQGIESRVYSCDMCLFETSTVSQLRTHYKERHTVQPTEVQLRPSWTGEPTTTRGVAAKQQTPAKILNHTDIPLGIKYPPGVLETQAPLPQPVVHQPMPDPMQQTEPMATTSTTITESGDINVVVDATPLFYAATSNSLLVTNPAPVTTVEETTGTASNHAFGIFPEISEGNLPVNEAVQQAPANSSSVSVFGDMQDFIDNTDVAAICTIPADGMPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEDDTVADEEDEADNEDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIKHYKTVHKRMPTRDMVQAKGDKVSVARTNIEKLYPGRIKNPMLMCAKCPFECESDSEMRKHLNAHHGINDGVSEHANEVFIIRKLPFECPRCIRSFAAKTTLSRHLQRSHLVDTIIEMQTPHCGEAITTTMATSSSTISEPVNSVTVDGQHNEMMQTDVGAEKMTEALGNGDGNEGGTDDGTGVKAEPAVPEEELDPVTLDAATAVTTTAIAAAISAAAAATATSLESPVATTASSSTTLFPTPTPFDFDYDIMRDEAQQSSPNIHDVSKALSDNASSSCPINESYKLLSTTALETSPAKGLRSNSRLHRSSIHICKLCNQTFDELGKLVKHEMELHSNTERSRWGYQHKCAICNTSYRTLTLLKFHMKRHSNRKSQCKLCPKSFVTIAELERHTKAKHSKDKTLRCFMDGCRKTFAFKHHLIRHQKASHLSTRYICPVCNKEEKSNVHLKNHMSVHKGEITYKCPKCDRSYLRRGRLVTHALIIHDLRFTTEELGNLSSLATNQARPNDLKVATPVGLLDGRKDVSGASEENGQP
Protein: F-BAR and double SH3 domains protein 2 (Protein nervous wreck 1) (NWK1) (SH3 multiple domains protein 3) (Q3USJ8)
Organism: Mus musculus (Mouse)
Function: Adapter protein that plays a role in endocytosis via clathrin-coated pits. Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor. Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling. Recruited to clathrin-coated pits during a mid-to-late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits. Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate (By similarity). When bound to membranes, promotes actin polymerization via its interaction with WAS and/or WASL which leads to the activation of the Arp2/3 complex. Does not promote actin polymerisation in the absence of membranes (By similarity).
Subcellular location: Cytoplasm {ECO:0000305|PubMed:23437151}. Cell junction {ECO:0000250|UniProtKB:O94868}. Membrane, clathrin-coated pit {ECO:0000250|UniProtKB:O94868}. Cell membrane {ECO:0000250|UniProtKB:O94868}; Peripheral membrane protein {ECO:0000250|UniProtKB:O94868}; Cytoplasmic side {ECO:0000250|UniProtKB:O94868}. Cell projection, stereocilium {ECO:0000269|PubMed:23437151}. Note=Partially localized at clathrin-coated pits at the cell membrane. Detected at the cell membrane at sites around clathrin-coated pits, very close to the clathrin-coated pits but not an intrinsic part of the clathrin-coated pits. Colocalizes at cell-cell contacts with CDH1, but is not detected at tight junctions. {ECO:0000250|UniProtKB:O94868}.
Interaction partners:
- PDZ domain-containing protein 7
- Intersectin-1
- Actin nucleation-promoting factor WASL
- Actin nucleation-promoting factor WAS
- Intersectin-2
Sequence:
MQPPPRKVKVTQELRNIQGEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGIQKLASQYLKRDWPGIKTDDRNDYRSMYPVWKSFLEGTMQVAQSRINICENYKNFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKYFETEQMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNTKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAIQNTFQFLLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATRVAREHKNIVHQQRVLNELECHGVALSEQSRAELEQKIDEARESIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQVMEELENERWARPPAVTSNGTLHSLNADAEREEGEEFEDNMDVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIEDGDMEDWVKARNKVGQVGYVPEKYLQFPTSNSLLSMLQSLAALDSRSHTSSNSTEAELVSGSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFSGRIGVFPSVLVEELSASENGDTPWTREIQISPSPKPHTSLPPLPLYDQPPSSPYPSPDKRSSQFFPRSPSANENSLHAESPGFSQASRQTPDTSYGKLRPVRAAPPPPTQNHRRTTEKMEDVEITLV
Protein: Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III) (Hexokinase-C) (P27926)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate.
Interaction partners:
- Glucose-6-phosphate isomerase
- ATP-dependent 6-phosphofructokinase, liver type
- Uncharacterized protein.
- Glucose-6-phosphatase catalytic subunit 1
- Glucose-6-phosphatase 3
- Glucose-6-phosphate 1-dehydrogenase
- Phosphoglucomutase-1
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
- Mannose-6-phosphate isomerase
Sequence:
MAAIEPSGLHPGERDSSCPQEGIPRPSGSLELAQEYLQQFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKEHSVETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNIDVVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGVLFGGCASPALLSQNSILLEHVAKMEDPATGIAHVHTVLQGLGLSPQASDAELVQRVCMAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETVMLLAPECDVSFIPSVDGGGRGVAMVTAVAARLATHRRILEETLAPFQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEGSVQITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLSGQSLPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTVGTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPGDSGHMCINMEWGAFGDDGSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQCLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLTLTSDDALMVLEVCQAVSRRAAQLCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTVRKLAPQCTVTFLQSEDGSGKGAALVTRVACRLTQMACV
Protein: Unc-13 homolog D (K7EN81)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATLLSHPQQRPPFLRQAIKIRRRRVRDLQDPPPQMAPEIQPPSHHFSPEQDALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTVHLHLLQQLVSHEVTQHE
Protein: AT3g56990/F24I3_70 (Embryo sac development arrest 7) (Q9M1J9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- Probable U3 small nucleolar RNA-associated protein 11
- AT1G07840 protein
- F18K10.11 protein
- rRNA biogenesis protein RRP5
- Nucleolar protein
- Protein SLOW WALKER 1
- Uncharacterized protein At3g06530
- Transducin family protein / WD-40 repeat family protein
- Bystin
Sequence:
MTSYGDRLKSTSINGVKLYNVSSAPNVPTWLNPKKQRALRKNPHYMQRVELIQELKFETATTRIKATPDGEYLIASGIYPPQVKVYELNQLALKFERHLDSEIVDFEILDDDFSKLAFLCADRSINLHAKYGKHHTLRIPRMGRDMTYDSWSCDLLCAASSPDLYRINLEQGRFLSPLSTQSPALNVVSRSNLHGLVACGGEDGAVEFFDMRMKSSAARINAVTHGGDAAAEVTAIEFDDSEGLQVAVGSSAGKVFIYDLRTSTPIRVKDHMYESPILNIKWQRTLNTQQPKLITTDKHIVRIWDPNTGEGMTSIEPTQGGINDICVFRGSGLMLLALDSSLIPSYFIPELGPAPKWCSPLENLTEELEESAQTTIYDNYKFLAMEDLEKLQLTHLIGTDLLKASMHGYFINYHLYKKALAVIEPFAFDDYLERRKQEKLEEQRTQRITKKRRLPKVNRDLAARLHGDESEEENKTAEDGEATKKVLKKKKPILTDEHFVDGRFGSMFQNPDFQIDKDSYEYGVLHPVASSKKQPSLLDEHFEAVSDDDENSDSDASQPSDDEADDGDATRPSKKARTPKLYEVKDERHAAAYHNRTSLAKEDSLPMGERVKAIENRRGNFGGSKDIKFGPGGSREFSFKARGSSKYKEDRDDEYEDGQRNKRRGVQSLGLKSTNIRGGFRGRGGGGFRGRGGGGSRGKGGRGGGRGRGRQ
Protein: Nuclear receptor corepressor 1 (E7EVK1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XSVESIPSLRGSITQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
Protein: Tumor protein 63 (p63) (A0A0S2Z4N5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU003304}.
Interaction partners:
Sequence:
MNFETSRCATLQYCPDPYIQRFVETPAHFSWKESYYRSTMSQSTQTNEFLSPEVFQHIWDFLEQPICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHEFSSPSHLLRTPSSASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMDARRNKQQRIKEEGE
Protein: Rotatin (Q86VV8)
Organism: Homo sapiens (Human)
Function: Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:22939636}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843}. Note=Colocalizes with the basal bodies at the primary cilium.
Interaction partners:
- SCL-interrupting locus protein
- Protein phosphatase 1 regulatory subunit 35
- Centrosomal protein of 192 kDa
Sequence:
MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERQLFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLVDVGAVEFLSKLRSNVEPNLQAEIDGILDGLFLLPSEVPALSSASYQTNQTELSKNPEILTGYFPQDKSNFQQMEVPPRPVVNQTVKCLKFSTFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQSLLSLLKLAFGDGKHRLALQSVSCLQQLCMYLRNRLNFHRDPGFFSNKHDTVSQNSSLSYCHEARGTHHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAASSSGSSSHAHVNSRISVHSPLDMGHIDLPELETEDTLELQFQQLSLPQFCVSILESAVPLLRTGSRQVIIRVLELLTEDMTLIGEAISTDIWDDSSLFGIDMKEKLLLVLGALGETMCYHKSSISLEQPEVMLVHHRMAFISISLFAVRLLQTLLPVEKASEFLSEPMSTALFLLSLDMPISLEYPNIHEAVVAYLEQLNSENYSIYKRTAEAVYSIECTCNFLSDIGKEGEKNLLELVELADQALRSFSYHQHFPLIKEIISICSKIWKSAQASPLLQGESQKVLLHMLSHPLPRVKAETYHCCLEITKECLGVHNVTKPVSSLCNGIHFLLHPKVLYEISVFGIQEPESEVNTAAKAILLYLLQGRLMMTALTWNKFIESLCPVIPILQGYADTEDPLGNCILLLSKASSDTEEMLPCTTRLKSMLRLLLVKKPSVRSLALKLLAFHLTSEEGADTKRPLIDARVLSRVTDLFIGKKPIELRLDDRRELVIKLETVEKVYEIFTSDDVDLVLRKSAAEQLAVIMQDIKMHAVVKKLCLIDKIIEYLNECVSQDGKVVECLVQPCLTLLRKVLCGDPVMRVSLSQQSSLLTVLFRVSLIFHEDCSVVTEVGALFCLLLFDEVSRMDMWSVNPSNKPSLPSVFSLPVSVFRRYHLPVHVIGHHAVSPYSIVLPLSADCLALKPVSDMLRIAWNLSWYHGSDNLLKQMNSETKTQEILDALKLSTEDILTLKITHMASGLQDCLHSIVQAATHREVRAAVTRMSFYLLNDRLSLKGCPGPCGVTLKSLAWHTALNRFLQVLPACTEDEKLLIDIIHFLNKLIKEQRKNSSLELLNWILELLLRHSANPLLDLLVLTESQAREETDDIRTAVRQQLQKELIALFDTLLLNFMEVTDRKCSELLYVFQTQLALKLLQCLKVTDAPHFYGLPSLERTLRGMANLTAFPGWSSHSPLTKPLDICVKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTILCLLHLSHEMMAQAGSLEWMSLWFLPLGSHSEEHIPTQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTLETGCVALANSCQNISGGLWGTVVNILLDQSECSMVRREAAFILQNLLVIPMPTEIIKDYTWQGPCVHDEDSGLSLIGKPALQALLYHCHFYEHLNQMVKHCYLGRCMFDLNFSAFDRNSESNDLNGLDDSFKFWRAPSRTSQDRDPSSLSTSETTVAPSLGSTEFQPLVQSTTLLPEASHDQFVAQGHQESTSPRPPHDSSLSAPLPKLCVFVTPSLLSAMCSLLDNLLTIAPRDTAKAFRQAHLIELLCSIADATLIQTCVQELRALLPSSPPAEHTQAQVSFLLEYLSSLSRLLQSCLLVEPDLVIQDELVKPLITNIIGILTICTKDVLDKELISAFYHTWTHLFNLLAMLLRKAGAITLPFVTVALAKHWTAAIDMFCTCAGLSATCPALYTASLQFLSVLLTEEAKGHLQAKSKTHLCCSPTVASLLDDSQENQKSLEQLSDVILQCYEGKSSKDILKRVAANALMSLLAVSRRAQKHALKANLIDNCMEQMKHINAQLNLDSLRPGKAALKKKEDGVIKELSIAMQLLRNCLYQNEECKEAALEAHLVPVLHSLWPWILMDDSLMQISLQLLCVYTANFPNGCSSLCWSSCGQHPVQATHRGAVSNSLMLCILKLASQMPLENTTVQQMVFMLLSNLALSHDCKGVIQKSNFLQNFLSLALPKGGNKHLSNLTILWLKLLLNISSGEDGQQMILRLDGCLDLLTEMSKYKHKSSPLLPLLIFHNVCFSPANKPKILANEKVITVLAACLESENQNAQRIGAAALWALIYNYQKAKTALKSPSVKRRVDEAYSLAKKTFPNSEANPLNAYYLKCLENLVQLLNSS
Protein: Uncharacterized protein (A8IPZ5)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Interaction partners:
- ODAD1 central coiled coil region domain-containing protein
- Uncharacterized protein
- AAA+ ATPase domain-containing protein
- Outer dynein arm-docking complex protein DC3
- Uncharacterized protein
- Uncharacterized protein
- PLD phosphodiesterase domain-containing protein
- Mr19,000 outer arm dynein light chain
- Tubulin alpha chain
- Tubulin beta chain
Sequence:
MAQKSTLKLPRLRTKEELLKTSPELCKLLGEDSDDGRSMSPFTAPPPAGTVKPPSRGLPAVSTKATKGPGMDTPRGLGEEELTEEELLRLELEKIKNERQVLLDSIKLVKAQAGTAGGEAQQNDIKALRRELELKKAKLNELHEDVRRKENVLNKQRDDTTDASRLTPGELSEEQAYIQQLQDEMKQIDEELVEAEAKNRLYYLLGERTRREHLAMDMKVRASQQLKKDSADDLYTLTAHFNEMRAAKEQAERELARMKRMLEETRVDWQKKLRERRREVRELKKRQQKQLERERKMREKQLERERQERELQAKLKMEQDSYEMRVAALAPKVEAMEHSWNRIRTISGADTPEEVLAYWEGLKAKEEQMRSLVSLAEQRESSAKSEIAALLENRSGMYEKGSAAAADVGEGSEERATLITEVERNMEGAKGKFNKLRSVCIGAEQGLRSLQERLMIALEEIHPDQLRASHMKGGHDAKARGKGAASAGARRGSAHAHTPDRNKRGPATGSRSQSPALVPHSPAGDKPSSPLHGTSPEHGHEPIPEGAEELAGEAEMVSPLGADGNTIDDEHFFPELPELLTSVTDRLNRVLVLAAELDAQEPAGAGEDGLPLSGEPGADGAEGAAPASPSRGAPEGLSESERTLVKGMNRRTWTGAPLLETINASPSEAALTLNIKRKKGKKKEQQVQPDLNRILGYTGSDVEEEEPESEEETEEEANKDDGVVDRDYIKLRALKMSQRLANQQRAIKV
Protein: UDP-glycosyltransferase 84A2 (Protein BRIGHT TRICHOMES 1) (Sinapate 1-glucosyltransferase 1) (AtSGT1) (EC 2.4.1.120) (Q9LVF0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sinapate glucosyltransferase (SGT) required for the biosynthesis of the glucose ester sinapoylglucose and subsequently sinapoylmalate and sinapoylcholine. Is the major SGT activity in plant. Plays an important role in sinapoylation of anthocyanins. Sinapoylglucose produced by UGT84A2 is a significant source of sinapoyl moieties for anthocyanins. Indole-3-butyric acid (IBA)-specific glucosyltransferase that catalyzes the glucosylation of the auxin IBA, but not indole-3-acetic acid (IAA). May be involved in flowering regulation through IBA-mediated transcriptional repression of the auxin-response factors ARF6 and ARF8 and downstream flowering pathway genes. Can glucosylate the phytotoxic xenobiotic compound 2,4,5-trichlorophenol (TCP).
Interaction partners:
- Serine carboxypeptidase-like 8
- 4-coumarate--CoA ligase 3
- Aldehyde dehydrogenase family 2 member C4
- Serine carboxypeptidase-like 19
- 4-coumarate--CoA ligase 2
- 4-coumarate--CoA ligase 1
- Flavone 3'-O-methyltransferase 1
- 4-coumarate--CoA ligase 4
- 4-coumarate--CoA ligase-like 9
- 4-coumarate--CoA ligase-like 7
Sequence:
MELESSPPLPPHVMLVSFPGQGHVNPLLRLGKLLASKGLLITFVTTESWGKKMRISNKIQDRVLKPVGKGYLRYDFFDDGLPEDDEASRTNLTILRPHLELVGKREIKNLVKRYKEVTKQPVTCLINNPFVSWVCDVAEDLQIPCAVLWVQSCACLAAYYYYHHNLVDFPTKTEPEIDVQISGMPLLKHDEIPSFIHPSSPHSALREVIIDQIKRLHKTFSIFIDTFNSLEKDIIDHMSTLSLPGVIRPLGPLYKMAKTVAYDVVKVNISEPTDPCMEWLDSQPVSSVVYISFGTVAYLKQEQIDEIAYGVLNADVTFLWVIRQQELGFNKEKHVLPEEVKGKGKIVEWCSQEKVLSHPSVACFVTHCGWNSTMEAVSSGVPTVCFPQWGDQVTDAVYMIDVWKTGVRLSRGEAEERLVPREEVAERLREVTKGEKAIELKKNALKWKEEAEAAVARGGSSDRNLEKFVEKLGAKPVGKVQNGSHNHVLAGSIKSF