wanglab/gogpt-training-data huggingface dataset:
Protein: Paired box 7b (Paired box protein 7b) (C0M005)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MSSLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQTQKQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRSTVPSGEASSVSSISRVLRARFGKKDDEDDCDKKDDTGEKKTKHSIDGILGDKGRMDEVSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPTYQLPESSYPTTTLPQDVSGTVHRPQPLPPSTMHQGGLSSDSSSAYGLSSNRHSFSSYTDTFMSQSASSNHMNPVSNGLSPQVMSILSNPSAVAPQPQHEFSISPLHSSLEASNPISASCSQRSEPIKTADSLPSSQSYCPPTYSTTSYSVDPVTAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLQVETGQAY
Protein: AT27789p (Glorund, isoform A) (Glorund, isoform B) (Q9VGH5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoprotein 87F
- FI21236p1
- Heterogeneous nuclear ribonucleoprotein 27C
- Uncharacterized protein, isoform C
- Poly
- LD40489p
- LD32469p
- Heterogeneous nuclear ribonucleoprotein K, isoform C
- LD29830p
Sequence:
MSNADVQFNYGQQGNGDNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHGTAFVVKLRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKRATGAGGGVGGRPGPYDIRDRGANRGGNDFGGGRNDWGNNGNFGVGANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIELFYDGKTRGLNGGEHGGGNGGGGMGNNGGGNFSRRI
Protein: Calcium-binding protein 8 (CaBP8) (Calneuron I) (Calneuron-1) (Q9BXU9)
Organism: Homo sapiens (Human)
Function: Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000305|PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305|PubMed:19338761}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:19338761}. Cell membrane {ECO:0000305|PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305|PubMed:19338761}.
Interaction partners:
- Neuronal calcium sensor 1
Sequence:
MRLPEQPGEGKPENEKKGDGGALGGGEEPPRSQAPDFPTWEKMPFHHVTAGLLYKGNYLNRSLSAGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNTIDSIFWQFDMQRITLEELKHILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFAMAFIISVMLIAANQILRSGME
Protein: tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) (tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL) (P0AGJ7)
Organism: Escherichia coli (strain K12)
Function: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. Recognition of the target requires a pyridine at position 34 and N(6)-(isopentenyl)-2-methylthioadenosine at position 37.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01885}.
Interaction partners:
- Ribosomal RNA large subunit methyltransferase H-methyltransferase)
- tRNA
- tRNA
- tRNA
- tRNA
- tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC
- tRNA-specific 2-thiouridylase MnmA
- tRNA U34 carboxymethyltransferase
- 23S rRNA
- Uncharacterized tRNA/rRNA methyltransferase LasT
Sequence:
MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRLRRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPETRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD
Protein: M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A) (P30304)
Organism: Homo sapiens (Human)
Function: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Interaction partners:
- Serine/threonine-protein kinase Chk1
- Cyclin-dependent kinase 2
- Serine/threonine-protein kinase Chk2
- G2/mitotic-specific cyclin-B1
- Cyclin-dependent kinase 1
- G1/S-specific cyclin-E1
- Cyclin-dependent kinase 6
- G1/S-specific cyclin-E2
- Cyclin-dependent kinase 4
- Serine/threonine-protein kinase PLK1
Sequence:
MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
Protein: Protein arginine N-methyltransferase 1-A (xPRMT1) (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1-A) (Q8AV13)
Organism: Xenopus laevis (African clawed frog)
Function: Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in target proteins. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation (By similarity). Methylates cirbp to regulate its subcellular location. Acts transiently during metamorphosis as a transcription coactivator, enhancing thyroid hormone (T3) receptor (TR)-mediated transcription by enhancing TR binding to the T3 response element (TRE), and histone modification through recruitment of other coactivators.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9JIF0}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9JIF0}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9JIF0}. Cytoplasm {ECO:0000250|UniProtKB:Q99873}.
Interaction partners:
Sequence:
MAEATTCNMENFVAKLANGMSLRTPIEDVNSAPPEGGVKTNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAIKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIYARDKWLTPDGLIFPDRATLYITAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVSNACLIKEVDIYTVKVDDLSFTSPFCLQVKRNDYIHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMKPNAKNNRDLDFTFDIDFKGQLCELSCSTDYRMR
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q0V7S5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized aarF domain-containing protein kinase At1g71810, chloroplastic
- Kinase with adenine nucleotide alpha hydrolases-like domain-containing protein
- Uncharacterized aarF domain-containing protein kinase At5g05200, chloroplastic
- Receptor protein kinase-like protein ZAR1
- Protein KINASE OF THE OUTER CHLOROPLAST MEMBRANE 1
- Protein kinase superfamily protein
- Probable serine/threonine-protein kinase At1g01540
- non-specific serine/threonine protein kinase
- Protein ACTIVITY OF BC1 COMPLEX KINASE 3, chloroplastic
- Protein ACTIVITY OF BC1 COMPLEX KINASE 1, chloroplastic
Sequence:
MEPWIDELTDDLQSVSFTSAGTTVNRSTSSGSRSSSSAAALTPAPSAHGSFSSSKLPPSLRSSLSLSDLRFRLRLGSGDIGSVFLAEFKSLTAVTETTAVKLPLLAAKVMDKKELASRSKEGRAKTEREILESLDHPFLPTLYAAIDSPKWLCLLTEFCPGGDLHVLRQKQTHKRFHESAVRFYVSEVIVAIEYLHMLGIVYRDLKPENVLVRSDGHIMLTDFDLSLKCDESTSTPQIVLNRNNLPNGSSDQNENQGMDHRQTTSSSCMIPNCIVPAVSCFHPRIRRRKKKTDHRNNGPELVAEPVDVRSMSFVGTHEYLAPEIVSGEGHGSAVDWWTLGIFMFELFYGTTPFKGMDHELTLANIVARALEFPKEPTIPSAAKDLISQLLAKDPSRRLGSSLGATAVKRHPFFQGVNWALLMCTRPPFLPPPFRKELLSDDICPETHVDYY
Protein: Scarecrow, isoform A (Q7PL95)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MSSHGLAYTTRIERKSYRELQINRDQYFVTAPNEEDLVMSLSPKDTLIHTAISQHHQVDTSTKLNTNETSTQNTVSTAAAAAVAHHHHNLSSIHHLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGNNSSSQSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGLNLITGDAPNSHSPDTSSSLLASYGTVGGSNVAMLQQPCNNTLMSNSLAMAYRNQNNFISNGHQQQCGGYLPLQGRAW
Protein: Protein MICROTUBULE BINDING PROTEIN 2C (AtMBP2C) (Movement protein binding protein 2C) (Q9LEZ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Prevents homeodomain proteins (e.g. STM) association to plasmodesmata and, consequently, cell-to-cell transport. Binds to RNA. Alters STM RNA binding capacity. Regulates cytoskeleton (e.g. actin) organization that determinates cell shape. Regulates stomata patterning and drought tolerance. Involved in restricting tobamovirus (e.g. oilseed rape mosaic virus) infectivity, probably by interfering with cell-to-cell virus movement.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17965274, ECO:0000269|PubMed:19074626}. Note=Microtubule-associated and stabilizer (PubMed:17965274, PubMed:19074626). Localized in cytosolic punctae when associated with STM (PubMed:17965274). {ECO:0000269|PubMed:17965274, ECO:0000269|PubMed:19074626}.
Interaction partners:
- DEAD-box ATP-dependent RNA helicase 36
- Protein NUCLEOLAR FACTOR 1
- Pre-mRNA-splicing factor SYF2
- Nucleolar-like protein
- KRR1 small subunit processome component
- U3 small nucleolar ribonucleoprotein protein IMP3
- Nucleolar protein
- U3 small nucleolar RNA-associated protein 18 homolog
- F18K10.11 protein
- Pre-mRNA-processing factor 17
Sequence:
MYEQQQHFMDLQSDSGFGDDSSWLAGDDDLRLSPHQSAAGTNSGNENLDRRLLKDLVEMVPLIEHYMEHKERSSFKRRGSMIYTKMPSKESLSRRGRNASQTVPGRKKRDQEGNDDVMNNSREDDENAKALAGAEKEEMSRLREQVNDLQTKLSEKEEVLKSMEMSKNQVNEIQEKLEATNRLVAEKDMLIKSMQLQLSDTKIKLADKQAALEKTQWEAKTTGTRAIKLQEQLDAVEGDISTFTRVFETLAKTDSKKPDRDYDAVPYEFDHLPYLDDVDETDLRKMEEARLAYVAAVNTAKEREDEESLVMAAQARAYLQSLAFTY
Protein: Pericentrin-like protein, isoform J (M9PFP0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
Sequence:
MADQRTTTTTTTTATTATTPSSANILATTATTTTTTSSSIEEEIEEAIEISEVEEQLNTPLESLSEAAAYARPKDEQSSAKSLSSNPAEDEDADEFRIDDAQLSGGQLAQHFLVDEDESEEGSDLPAASKVEVSLSSNDDDFDISLPLEQRKPVHSLHEDDESVDQSLSNQSTTDDVSELVEEPVHEMDDKTDGSAAISASAPQETQVDESQITDEQDHSMEEIVATNESIEVTYEAEETVNTSQKQDLITDLDEESEDQVHVDNRPTSTLQALKLPALQQPQIVERKAATALTTLRLQADVLEPLELTILEMDDDENEEDDDDEESSLQLMKLRLMAMNQQMIVDNAPKLSPTEAEQTQVTSSSNNLEIKQMERVPLTEFSKDVLEDITEESERLLSMSTTMEEEQDPPSLSLDESKTLLQPGAHKTGGSSSSLVSLNMLKQLEAKVQELHTQLETKDNCLASLNLQLETARRESSAGPASARDSSSLMTNSTEYRTLQEELGGPTLDIYVEMSRRDELIAKLTDSLQQSLNVRDKLQVDADRLGGEVQNLRRQLQETLDAVKRSSAVWPDQECNPGQRISEISMDLISESDDDLDRHFLTDNEERGSRSSKERQLTQLQTNEELGLQASNPEWTPTFSKQIEQFHTYLLPTEQRIFQMVQRKFDDYLNQQITLCRDLGAQELKIARDQWESEKLTSEQNQQAAHAKQMEDLRKYFEHKCADLEKQFSDDVFSHKSQHQTGDSSSECSEVDQLPEEGAAAVSSKEPSPRKRKRAELLLSPSHRQMTPCGLDSLGENTGKTEKDNTADIADLKIFYQTHIKELKRAHEDQVRKLSDRIKFYERQQGDDDYKPATESPERTCPDQESAGGVANTSLIIIDEDELNFNNESQVIQRIIEEYEKRLQEQLALARQDIATELEQQIKSLLSENTVDDQHWPKELILLREKFTAKSQLEITQLNIKHAEEMSRLKLEFEKQLNRKNKRHLTFDAARDLEQVICERDGLRELSKSFRSVLCRLAKCVAHCEEDLNATLSEEVQRLLFHSRSQDGGDDLEATISSSLNNTKHMLRVPDVHSLLEVVEDPSLVQFIDSKSNEEPSEDFDLNDCLERLKSEASYLLHLSEDLHKQRTHDESSEHLDEPEKQEHELCCEAEDGLKTTGAVNQQVLSKFLRTNSLNDQQMGVANQRKNSNPEAGKTHSSLPPDLQEHAGNASELSFQLVQLKNRLIKSEADRQNLQQQLSRTIDRNAELGQELQALRDQLSQLNSLNHTDYNEGYGLGTMKSLQEQGLDQSSASFLALQERARHLLSSSPVKEQPSRDHGNSTVILLQMIEDFCREGDKVVEFSKKDREDLQSQYAQLESQFREVNQQLCESNAKRDKFEVELKASIDKIFVLREIISELETQVQTKALNEEVLAEKAQQLEEYVSLQMRDNDILQQEVHSLKTDIGEGYQSRIRVLEEKLKQSGPTAEQGVVLSQVAEKLRDIETTLDQKTKALESLHNSNATSNSASLSVTEDVSIHGSKEPTAVGSPSHPSLTVEGVQRVTEKLDRHTRVEEAAIKRIRDLEMQVHQMRAGCVELQHERDTLQGRMEEQTQRISTLQNRLEEQRQRAEQLHRTGTSDLNTRVHELQGEVQNLYEQLAARDKQMANMRQQLQRSKEEITRLETEVEVRTQPDRSLVNKLQAEVQQKGAEIVKLKDKIRTEMINRLAIPDLMETMLADKNDEIDHLRDQLEAKEKELQASQQEASQISSPSGAAGKQEGSGGKLSARTLSDIGSITEFPEPDVERRAAMRSLTALQMSEGAGGFLHQTMETSKEAVANLTHKRTDDLSGFIVPYPVNTFEHPHYFQALGVTAQSTDGLTPGLVPRQINFSNLTEDSKLKTTSLLMHTPELPRPTTPPEIHQLRVKLSDLQTEKQRQQSELEKKLQDLQKELEQEKEKLSRQAQTLQSYEESEAKYRLRIENLESKVLETAAQAASDRENLRKELNCVSAAHEQCENAAAARKRELEKLNSEVKVKADQLHAALRRCADLELQVLTLERDLERLKNSDNSSKQYSVDEIAQQVEKELNYSAQLDSNILKAIESEEENNLDKKLQKGVQTEEETLPGTGNGTDDENFTGERELLNQLEALRAQLAVEREQCEAMSKELLGEKQHSQDIQEQDVIIIEAMRKRLETALDAEDELHKQLDQERERCERLQTQLTSLQRAESRRNSSLLLKSPGDSPRKSPRADFESELGDRLRSEIKLLVAQNERERERSADAQRSSERERQRYEKELQERVAYCERLKQEMEKLSRDKESAETELEHFNERLTLQASEIESLEARLVTLQEAETRRANTRTRQHQENVKLQAEIHELKSKLLAAEAARDCLDQKVTQLRFDVSRSGQREAKLAEALAQANDRLAHSTDDNVPAQFMQKMKEINALLAENTQENRQMAETVQFLVGERIALQKKCEELGGAGNTNVTELEERCRQLIGRYLRVESHRKALVYQKRYLKLTLEGYQASEQLALQNLRGGAEQPPQRNIKKKFKTVALAIIAIQRIKYIGRIWHTGKRIVSKSVFTITQQRSPGLNLNVAPPQSPLPGPNSNLPTNNNNLMGRLSYAPLSPPMVNFSTVQPIMLPSDFTLQAPTTSLQTTIANNNSENTLPSLARLDWPTMQKPKRAHARHH
Protein: F-box protein At1g61340 (Q8GX77)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- AT3g54190/F24B22_150
- Transducin/WD40 repeat-like superfamily protein
- Protein S40-2
- At5g43150
- Putative pumilio homolog 16
- Probable acyl-activating enzyme 8
- DNA ligase
- RING-H2 finger protein ATL13
- Pumilio homolog 11
- Putative pumilio homolog 10
Sequence:
MALGKKRIVTQKPNLRQRRDVDNGGLGLGLEFVQYKRGFGRKRILISSGDEMEDSIFTSPVGKKLCDDKTTSVAEGQSRELEDLPLDILVRIICGVEHEDLKQLFHVSKTIREATMIAKQSHFAYSTPRKTSVFHHGRFGWDKPFDVEDDDEEIEAPGAPLQKRYRLSRINRNKDDSGVSVALFH
Protein: Surfeit locus protein 6 (O75683)
Organism: Homo sapiens (Human)
Function: Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Granular component of the nucleolus. {ECO:0000250}.
Interaction partners:
- Probable rRNA-processing protein EBP2
- RRP15-like protein
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- GTP-binding protein 4
- Ribosome production factor 1
- Protein MAK16 homolog
- Ribosome biogenesis protein BRX1 homolog
- Probable ribosome biogenesis protein RLP24
- Ribosome production factor 2 homolog
- Ribosome biogenesis regulatory protein homolog
Sequence:
MASLLAKDAYLQSLAKKICSHSAPEQQARTRAGKTQGSETAGPPKKKRKKTQKKFRKREEKAAEHKAKSLGEKSPAASGARRPEAAKEEAAWASSSAGNPADGLATEPESVFALDVLRQRLHEKIQEARGQGSAKELSPAALEKRRRRKQERDRKKRKRKELRAKEKARKAEEATEAQEVVEATPEGACTEPREPPGLIFNKVEVSEDEPASKAQRRKEKRQRVKGNLTPLTGRNYRQLLERLQARQSRLDELRGQDEGKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRRWEKRTAGVVEKMQQRQDRRRQNLRRKKAARAERRLLRARKKGRILPQDLERAGLV
Protein: PHD-type domain-containing protein (G5EGI1)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Retinoblastoma-binding protein homolog 5
- WD repeat-containing protein wdr-5.1
- Set1/Ash2 histone methyltransferase complex subunit ash-2
- JmjC domain-containing protein
- PAX-interacting protein 1
- WD repeat-containing protein wdr-5.3
- Dosage compensation protein dpy-30
- Multifunctional procollagen lysine hydroxylase and glycosyltransferase
- Anaphase-promoting complex subunit 4-like WD40 domain-containing protein
- WD repeat-containing protein wdr-5.2
Sequence:
MICIECGGTAFNNTELCENCMDVNRSGTMSLDMARQCDMSSSCGSCQRMITADSRQCTTCRKSYHLSCDSSDVSSLNNFVCISCRRRSQMLPDDVMLSASARPSRGQDAPLSPFSDPSVPQISLQMQPAPLPSSYPRSQDFNGDVYTQIAAMQQQRQQQQQNQVQQMLATQAQLMDEISDGGGTNDSDRNSSPFYQEASDYDEDFVPASTRGRGRGGGAKKKPGRGGSTGTRRQTNPGPSGFFSATQLQAMSGDFSHLHQPQQTSSTRGKRGKRGNGTSVPRQPGKGPGRGRGRGRGSAAAIAQLAQLQQVQYGAQGAPMFNGAPQLHPTQPTVAPTLPPSVTYQNVAPTAPPAPPALQTPLPDPLPSIVPSFQQAPQAVAIREVDELMLEDESSRQSGGSRSDEPEYIRTAIVCRVNDEFLQKACMCLVCGSIGKGPEGSMVACSNCAQTYHTYCVTLHDKLNSAVVGRGWRCLDCTVCEGCGTGGDEANLLLCDECDVSYHIYCMKPLLDKIPQGPWRCQWCSRCRRCNHKAASGNDLTSQGLCFPCASLRKCPRCERNYQLNEKLIRCSQCSKWQHGACEGLYTDEQLEQAAIDRMRCSACRPKRVQPSGFSDVDTVWCDYVALDKDAHEILKSKYTPSALKNHMMESVGYRESFDHYDDDYNPLEDSSDQVTPLPIPGQRGRGRGNPSGRRGMNRIGIGGFYAKLPRHRIQALTEEAAAAAASSEDSKQAKRPRKSRRSQLEDAYPPQIQEAFFGIKAVEGKVLVDTPVDEPFLAEFNGWYKRTRSTKAFELCMTASEMLRTDIDENEFLDCVGLPNMETDALDDFDFNLLEDFDVDEENDELENSLLGAPGNTEMKEDAAEGIEGSYGPTSFNLDQRPSTSSAGGSLGSQDPFHPGMNPANFAQHAPGVRNAIARSGSQTDNSERYQFSARWEEDEPNGLQATTAAVLYSNEKHGYLRQQFPNWVDRVKQIQKLWRTLNHEVRLDYVNRARDNRTRSGNRPRPRRTNVQSTDSPPPPQMGFKVPANPSSNMMGSSEQSMQPKQVFITHHLPMDVYQVYQDLKRVKFDRERLNGSLEEQLNKARKQKKNLAAKKRQMVKTQTAAPDYDGRNIDLNESDQQTLATLTEQIKVTQAEIELHRRDLKKHESNLSDFVMKHGILRNEHEVKREDVQLSAIRDQQYAAHADEMLAQQAQNQGLGQVHPPVLVAPQAAISLPMLNQQQQHHQRMMQMQMRGGPPGQFMMRAQPPQQPQINMHNHEIAKRMLMQQFRNAHPVMGGIRHDEITDPIMRDVYDCLEAIVFDVHTVAEREAMQAAGQQPPPPHIMQRMMQQHPGGPGGPRLIMPGQFPQLQGRRIPQQPPPVQLPQVDVDPPKTAAKRKKGGGNPKKNASSYPAAGEYDAWIEQMRMRFRLCPDIPKKQKEPRLNRPGCEFVSHGLTDMAVRATKKRTPLVGEFGAMRVKRGTRLFGNEERGEKSIMFQDLNLYQVEPQIRLFALYNNPLPTMEDDVFRDEEDQIIDKPTSALQKLLNKKRGASGAMDHIRSRARYMEETNIPPAPERGMFYENVEAEEEVTVELVFNTCDITEESSVDEKKDVCGRLHEQIRDLLAIKDEVAWSMEDTPPESPVSRSPEPEATVGAVQQTSSTSRAPSEATEREIKREVEEEAAPVAPEIKREIVEPSQSQNSSQCKNCQKALESHSSTSIVTVKAEKLNLAPTGSVVTTRAAPVPPGVPGAPGAPIAPSEEKTKEELASFCSKKCYYELASATRAPLTEEEVAAAEQHVSEEVYNKLKQVLTENIVKAVSQGKKPDPQLTSPRDTRCMMDEGRRENVTIVPVASLIGAVEAPKEAPSQRAAEAAEDWKAYTKSIWDSFVNIQQQHAHHILSPKIGVPHPPYHLDKRICVFCGGIGDGETTRCGRLISLTEFYWVHVNCALWSAEVFENQTGGLTNVDRAVLRAAQTACDHCKRPGASVKCHKMNCGVNYHVLCAMQNNGFFIKDRTFICKQHEKVSNQAIVGRLDALRRIYVKRDENTMLTRLFELTDGPTLCMRLGAFTFYKIGSITPKQLKRFHTKDYIFPNNYRITRLFWSPKSHRERMMFECIIEDRNNQPIFVVKSLEDPTICYKAVSASKAWQPIYEKVHQLREQQQGDSLKFFGSQICGETLFGLNENAITKITESLPGFDTIFTYQHRHQNSPVLELPLAENLMGCARAEPRNRTIGQHFRTKPQPMGGTHHHIGSASGLSSQATIIASSSSSANESLQSRQAATSVTSANSGRTRGVRSYYTEEAAARARAFGIPPEMASLSLRMETTQNAQTAFSAYQKMRREWKDRVYLARSRIAGLGLYAKVDISMGDFIIEYKGEIIRSEVCEVREIRYVAQNRGVYMFRIDEEWVIDATMAGGPARYINHSCDPNCSTQILDAGSGAREKKIIITANRPISANEELTYDYQFELEGTTDKIPCLCGAPNCVKWMN
Protein: Bradykinin-like peptide AR-10 (P84832)
Organism: Ascaphus truei (Coastal tailed frog)
Function: Induces relaxation of mouse trachea that has been precontracted with methacholine. May induce relaxation of arterial smooth muscle. May target bradykinin receptors (BDKRB).
Subcellular location: Secreted {ECO:0000269|PubMed:15922344}.
Interaction partners:
Sequence:
APVPGLSPFR
Protein: Amino acid permease 3 (Amino acid transporter AAP3) (Q39134)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Amino acid-proton symporter. Stereospecific transporter with a broad specificity for GABA, tryptophan and both neutral and basic amino acids. High affinity transport of cationic amino acids.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15361541}. Nucleus membrane {ECO:0000269|PubMed:15361541}. Endomembrane system {ECO:0000269|PubMed:15361541}. Note=Not found in vacuole membrane.
Interaction partners:
- WAT1-related protein At2g39510
- WAT1-related protein At4g01430
- WAT1-related protein At1g01070
- WAT1-related protein At2g40900
- Cationic amino acid transporter 6
Sequence:
MVQNHQTVLAVDMPQTGGSKYLDDDGKNKRTGSVWTASAHIITAVIGSGVLSLAWATAQLGWLAGPVVMLLFSAVTYFTSSLLAACYRSGDPISGKRNYTYMDAVRSNLGGVKVTLCGIVQYLNIFGVAIGYTIASAISMMAIKRSNCFHKSGGKDPCHMNSNPYMIAFGLVQILFSQIPDFDQLWWLSILAAVMSFTYSSAGLALGIAQVVVNGKVKGSLTGISIGAVTETQKIWRTFQALGDIAFAYSYSIILIEIQDTVKSPPSEEKTMKKATLVSVSVTTMFYMLCGCMGYAAFGDLSPGNLLTGFGFYNPYWLLDIANAAIVIHLIGAYQVYCQPLFAFIEKQASIQFPDSEFIAKDIKIPIPGFKPLRLNVFRLIWRTVFVIITTVISMLLPFFNDVVGLLGALGFWPLTVYFPVEMYIAQKKIPRWSTRWVCLQVFSLGCLVVSIAAAAGSIAGVLLDLKSYKPFRSEY
Protein: Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) (Q02779)
Organism: Homo sapiens (Human)
Function: Activates the JUN N-terminal pathway.
Interaction partners:
- Dual specificity mitogen-activated protein kinase kinase 7
- Huntingtin
- C-Jun-amino-terminal kinase-interacting protein 2
- Kinesin-like protein KIF3A
- C-Jun-amino-terminal kinase-interacting protein 1
- EVI5-like protein
- Cell division control protein 42 homolog
Sequence:
MEEEEGAVAKEWGTTPAGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPRVRKRKGNFKRSRLLKLREGGSHISLPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQKERVGGEERLKGLGEGSKQWSSSAPNLGKSPKHTPIAPGFASLNEMEEFAEAEDGGSSVPPSPYSTPSYLSVPLPAEPSPGARAPWEPTPSAPPARWGHGARRRCDLALLGCATLLGAVGLGADVAEARAADGEEQRRWLDGLFFPRAGRFPRGLSPPARPHGRREDVGPGLGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPPAPTPTPSPSTNPLVDLELESFKKDPRQSLTPTHVTAACAVSRGHRRTPSDGALGQRGPPEPAGHGPGPRDLLDFPRLPDPQALFPARRRPPEFPGRPTTLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQNQDSTVPLCGAHGSH
Protein: TATA-box-binding protein 2 (TATA sequence-binding protein 2) (AtTBP2) (TBP-2) (TATA-binding factor 2) (TATA-box factor 2) (Transcription initiation factor TFIID TBP-2 subunit) (P28148)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: General transcription factor (GTF) that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (By similarity). Interacts with TFIIB1 and is required for activated transcription and possibly basal transcription. May act as GTF of RNA polymerase I-dependent transcription and rRNA synthesis. Forms a ternary complex with PBRP1 and the rDNA promoter region.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P28147}.
Interaction partners:
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 7
- Homeodomain-like superfamily protein
- Transcription initiation factor TFIID subunit 13
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor IIA subunit 2
- Transcription initiation factor IIF subunit alpha
- DNA-directed RNA polymerase II subunit 4
Sequence:
MADQGTEGSQPVDLTKHPSGIVPTLQNIVSTVNLDCKLDLKAIALQARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVCTGAKSEHLSKLAARKYARIVQKLGFPAKFKDFKIQNIVGSCDVKFPIRLEGLAYSHSAFSSYEPELFPGLIYRMKLPKIVLLIFVSGKIVITGAKMREETYTAFENIYPVLREFRKVQQ
Protein: DDB1 and CUL4 associated factor 8 (V9GYQ9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRP
Protein: Uncharacterized protein (Q57WC4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSNREPMSPLPTQPTSVPSVASLKAVLTPQVVLQTAQASLELPKADEMWSNWYKESEDRFLDFISFDATEGGGNGGVVRSGSSHRTLSARRISGQFEEEVMKSWEEDWEDEDVEDTFDAVMGRIGRYEASRAASSQK
Protein: Alpha/beta-Hydrolases superfamily protein (At2g39400/F12L6.6) (Putative phospholipase) (O80627)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 1, mitochondrial
Sequence:
MVMYEEDFVLNSRGMKLFTCVWKPVKQEPKALLFLCHGYAMESSITMNSAATRLANAGFAVYGMDYEGHGKSEGLNGYISNFDDLVDDVSNHYSTICEREENKGKMRFLLGESMGGAVVLLLARKKPDFWDGAVLVAPMCKLADEIKPHPVVISILIKLAKFIPTWKIVPGNDIIDIAIKEPHIRNQVRENKYCYKGRPRLNTAYQLLLVSLDLEKNLHQVSIPFIVLHGEDDKVTDKSISKMLYEVASSSDKTFKLYPKMWHALLYGETNENSEIVFGDIINWLEDRATDSNGGLESQLKHKHDGFLKHK