wanglab/gogpt-training-data huggingface dataset:
Protein: Sucrose transport protein SUC4 (AtSUC4) (Sucrose permease 4) (Sucrose transporter 4) (Sucrose-proton symporter 4) (Q9FE59)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). Can also transport maltose at a lesser rate. May also transport biotin.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cytochrome b5 isoform E
- Cytochrome b5 isoform A
- Cytochrome B5 isoform C
- Cytochrome B5 isoform D
- Cytochrome b5 isoform B
- Monosaccharide-sensing protein 1
- Sugar transport protein 3
- Monosaccharide-sensing protein 2
- Bidirectional sugar transporter SWEET11
- Bidirectional sugar transporter SWEET17
Sequence:
MATSDQDRRHRVTRNRPPIARPSTSSSRPVVSPPRSKVSKRVLLRVASVACGIQFGWALQLSLLTPYVQELGIPHAWASVIWLCGPLSGLFVQPLVGHSSDRCTSKYGRRRPFIVAGAVAISISVMVIGHAADIGWAFGDREGKIKPRAIVAFVLGFWILDVANNMTQGPCRALLADLTENDNRRTRVANGYFSLFMAVGNVLGYATGSYNGWYKIFTFTKTVACNVECANLKSAFYIDVVFIAITTILSVSAAHEVPLASLASEAHGQTSGTDEAFLSEIFGTFRYFPGNVWIILLVTALTWIGWFPFILFDTDWMGREIYGGEPNIGTSYSAGVSMGALGLMLNSVFLGITSVLMEKLCRKWGAGFVWGISNILMAICFLGMIITSFVASHLGYIGHEQPPASIVFAAVLIFTILGIPLAITYSVPYALISIRIESLGLGQGLSLGVLNLAIVIPQVIVSVGSGPWDQLFGGGNSPALAVGAATGFIGGIVAILALPRTRIQKPIPLP
Protein: Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (P39944)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Serine/threonine-protein kinase AKL1
- Ubiquitin carboxyl-terminal hydrolase 4
- Polyubiquitin
Sequence:
MGSEQALSEVVESAKERFGRLRHLVQKFLDDDDVPQECLPLLQECAEIWSSYVDACQDITMQAPKEDANRLSKGFLRLNETAFLYYMIVYTLLEDTLPRLKEFSSNKDQNVRNLYGERIQLLHNDPNIERIRNVIENYPKFIQLQTIEPGKLSSMLHFHGDALLLIDVRPRSEFVRAHIKCKNIICIDPASFKDSFTDQQIESVSLITSPHSDITFFSNRDKFKFIILYTDTQLHNNFQQRQTRILAKILSQNSVIKPLSGTKILILENGFSNWVKLGGAYQSSVSETAHLTSSSSTPAFGSPQVPTGLFNQKSLSPNKDKSMPMVSMNTQPLLTTVQRPQLPLYYSDLPIIPQPSPNRNSPTVQKFSPHPPTTLSKLNTPSTIQNKANTVERISPDIRAAQAHAYLPPASNVFSPRIPPLPQQNLSSSRQTILNNSQVLDLDLIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGSKKHLKQLSDEEERMREKMSIRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPRVKTCNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYKGPKKGWYFFDDSLYRPITFSTEFITPSAYVLFYERIF
Protein: A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAM-TS 1) (ADAM-TS1) (ADAMTS-1) (EC 3.4.24.-) (Q9WUQ1)
Organism: Rattus norvegicus (Rat)
Function: Cleaves aggrecan, a cartilage proteoglycan, at the '1683-Glu-|-Leu-1684' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Aggrecan core protein
- Fibulin-1
- Metalloproteinase inhibitor 3
- Metalloproteinase inhibitor 1
- Collagenase 3
- Stromelysin-1
- Metalloproteinase inhibitor 2
Sequence:
MQPEVPLGSGKLKPCSDMGDIQRAAKFRSSQSAHMLLLLLASITMLLCVRGAHGRPTEEDEELVLPSLERARGHDSTTLLRLDAFGQQLHLKLQPDSGFLAPGFTLQTVGRSPGSEAQHLDPTGDLAHCFYSGTVNGDPSSAAALSLCEGVRGAFYLQGEEFFIQPAPAVATERLVPAEPKEESIAPPRFHILRRRRRGSGGAKCGVMDEETLPTSNSGRESQNTPDQWPLRNPTPQGAGKPTGPGSIRKKRFVSSPRYVETMLVADQSMADFHGSGLKHYLLTLFSVAARFYKHPSIRNSISLVVVKILVIYEEQKGPEVTSNAALTLRNFCSWQKQHNSPSDRDPEHYDTAILFTRQDLCGSHTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKHCASFNGVSGDSHLMASMLSSLDHSQPWSPCSAYMVTSFLDNGHGECLMDKPQNPIKLPSDLPGTLYDANRQCQFTFGEESTHCPDAASTCSTLWCTGTSGGLLVCQTKHFPWADGTSCGEGKWCVSGKCVNKTDMKHFATPVHGSWGPWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNIEDCPDNNGKTFREEQCEAHNEFSKASFGNEPTVEWTPKYAGVSPKDRCKLTCEAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTCKKISGTVTSTRPGYHDIVTIPAGATNIEVKHRNPRGSRNNGSFLAIRAADGTYILNGNFTLSTLEQDLTYKGTVLRYSGSSAALERIRSFSPLKEPLTIQVLMVGHALRPKIKYTYFMKKKTEPFNAIPTFSEWVIEEWGECSKTCGSGWQRRVVECRDINGHPASECAKEVKPASTRPCADLPCPRWQVGDWSPCSKTCGKGYKKRTLKCLSHDGGVLSNESCDPLKKPKHYIDFCILTQCS
Protein: Cwp66 (Q9FA27)
Organism: Clostridioides difficile (Peptoclostridium difficile)
Interaction partners:
Sequence:
MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIKISQAGWTKSESAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGVKNVYLIGGSIALSSEIEKQLNAENINFERISGNSRYDTSLKLAEKLDREKSISKIVVVNGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIAKSYVIGGTYSISSSVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTKNKNDLIDSLAVGVLAAKNSSPIILAGNKLDTTQKDVLNTKIIDKVTQIGGLGNEDAVKSIVDMQEKTKYTVETIEELNVAIKKADANDVIIFEPEKDTNISDSFKIATNKAITVEFDGVFKQSITIDMPNGDVKNFGEISDDIRIDNIKKGTLINEGSIQGIDIYSKNGCKIENTSDGDIWIITIDADAKDVYIENDGDITKISNNAPGVIIKNSGKIDLVNGNEQPAISGKKPTTNDTEYNDERARGLSVSTKPCSIPEKNRVRVTISSEPKSSRYKIYYRVVEDKPSAMYVGEKISVRSWDLASKSDGSFVEKAKNGSYIEVVEINTSTNKVSRWGRSNVTDDGF
Protein: EWS RNA-binding protein 1b (Ewing sarcoma breakpoint region 1b) (Q4QRG0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein M
- TAR DNA-binding protein 43
- DEAH
- Non-specific serine/threonine protein kinase.
Sequence:
MASVTNYSSYNQAGAQQSYGSYTAPPAQTYGQTAQQGYTQQDYSSYAQPAAAPEATYSQAAPSAGAYAQQQYGSTYGQAAATAAAAPAAYGTPQPGAYTQPAQSYGASSYTGSTAAPAAQASYGSQPGYSTQPAYSGYSQQPAASAPQSYSASSQPAYNQSAYSQPAGYSQPGYQAQQPGYGQQQQSAYGQGQPPQQHQQGPPAAYPPQGSSSYAQTQYGQQSAPQNDYQQNPYNSYSQGGVSGGYPGSQRGGYQDGGRDGYDRGGPRGRGMGRGGMGIAGDRGGFNKPGGPMRGGMDRDMGHPGEQDSENSTIYITGLTENATLPEMAEFFKHTGAIRINRRLNQPAINIYTDKDSGKPKGDATLSYEEPAFAKAAVEHFDGKEFQGRRLKVSMARRKPMIGGMRGGMPMRGGPGMDRGGMMGRGGERGGFPPRGGPRGGMGWNGGPQPGNVQKRAGDWECPNAGCGNQNFSWRMECNQCKAPKPEGLGTSPPFSPGGERGRGGMRGGRGMDRGGPGGMRGGWGGDRGGFRGRGGMDRGGFRGGSRGGPPMDRGRRGMGPPGKMEMRDHRQERRERPY
Protein: G-protein coupled receptor 52 (Q9Y2T5)
Organism: Homo sapiens (Human)
Function: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization. May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum. Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Probable non-functional immunoglobulin heavy variable 3-16
- G protein-coupled receptor 88
- Rhodopsin
Sequence:
MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
Protein: Antimicrobial peptide Xac-2 (Xac2) (Xylopinin) (C0HKQ6)
Organism: Xylocopa appendiculata circumvolans (Japanese carpenter bee)
Function: Antimicrobial and mast cell degranulating peptide which probably acts by forming pores in membranes. Active against Gram-negative bacterium E.coli NBRC 14237 (MIC=3.12 uM), against Gram-positive bacteria S.aureus NBRC 12732 (MIC=3.12 uM) and M.luteus NBRC 12708 (MIC=6.25 uM) as well as against yeast S.cerevisiae NBRC 10217 (MIC=25 uM). Has hemolytic activity (at 100 uM).
Subcellular location: Secreted {ECO:0000269|PubMed:28546807, ECO:0000269|PubMed:28855917}. Target cell membrane {ECO:0000305|PubMed:28546807}. Note=Assumes an amphipathic alpha-helical conformation in a lipid environment. {ECO:0000269|PubMed:28546807}.
Interaction partners:
Sequence:
GFVALLKKLPLILKHLP
Protein: Protein let-653 (Lethal protein 653) (Q27394)
Organism: Caenorhabditis elegans
Function: Required for epithelial tube development and shaping. Involved in the morphogenesis and function of the three unicellular tubes of the excretory system, the canal cell, the duct cell and the pore cell. Also plays a role in cuticle development, alae formation and shaping of the vulval lumen. Required for larval development.
Subcellular location: [Isoform b]: Apical cell membrane {ECO:0000269|PubMed:27482894, ECO:0000269|PubMed:33141826}; Peripheral membrane protein {ECO:0000269|PubMed:27482894, ECO:0000269|PubMed:33141826}; Lumenal side {ECO:0000269|PubMed:27482894, ECO:0000269|PubMed:33141826}. Secreted, extracellular space {ECO:0000269|PubMed:27482894}. Secreted {ECO:0000269|PubMed:27482894, ECO:0000269|PubMed:33141826}. Note=Localizes to fibrils in the vulval luminal space. {ECO:0000269|PubMed:27482894}.
Interaction partners:
- Leucine-rich repeat-containing protein let-4
- LiPocalin-Related protein
- LiPocalin-Related protein
- Putative polypeptide N-acetylgalactosaminyltransferase 11
- Leucine-rich repeat-containing protein egg-6
- Leucine-rich repeat-containing protein let-4
- MARVEL domain-containing protein
- NOmpA Homolog
- EGF-like domain-containing protein
- GDP-mannose 4,6 dehydratase 2
Sequence:
MRHPLISLLLLIAFYSTSSEAFVPKCNSFYVRWPRVRLNFKAVAEARLSLKGCQSACSLGEDPVSPGKQLECAAVNHQASPDGFSHLCAVFQPHQLQNVDGYVEADDRFTFYWKYCLPSTRKCSGEYAFTYLSDRYMDQKSVIKWTTKANLEECLSDCLDEKSFECRSISFNRTDGGCHMSKDSQISRPEAIRLNNNPNYRIDYYENNCYNLSESFTFKHECRDNGISVSVKSRLPYTGAIYGLYDFFTCRTEPKEATEFDHFFPYQTVSKNCSDSIKYKGNEMVLEVVLSTDGIEPLYFITPEDLTYQAKCPISGVKAKDPANTKSSAHLDNRNKAMEASAHALFELLSKTGDDEALQNTFPLPLTTTTEVIRQVTTTTKKPSTTTSTKKLTTTTTTTPKPSQKPTTTTTKSPVVITTTTKTSPKPTTSPSTTTSTTTSTTIPPSTTTRKPANPRRSTIMSATSKVAIIVGKDSSFARARLFTTKHPSTQKIDVPTTTVQTSTTVPTTPSKTTATTTTTPKPTTTETATTSSSTTTVTTQKPTTVTSTTTLPSTTASTTTKTTTSTPTSPQTTTTHVGAPASSVASVAHDGSTLAGKPKVPVIFDIFHNGQPVEAVVVGTKISLSFRPHYPIPPEYVDVRGCQVEPIDPKYEWEHEPLFIIRDGCPADGVGLVCPPTHSEFGAKVSVEAFRYQTTGQVQYSCLVRICPFAPCPKNTCDDVEGCDSSYMHRYRRELSLEDIKKALEANPELASQFGISPSAFARNPSKSKNFTSVVEEQQRIALGGDYLVRRRLIVVNSEDQLRYYVRTGNI
Protein: Chascon, isoform A (Chascon, isoform C) (Q9VX26)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MALSKTIKSKAGAKDEQNELVEFEPKDDEESNEVTASNCDTEAITKEEEWITKRKTELTTTRQIETRVKRQVKLQDGKVIEDSGPIVSTNTTEDTDKQETETTEKRDLDLPDDLDGNAQLIDVAALQAGAINETQLAQIQEVFGPADGAGKLVKRMVPRPVDGLVRQTDDKRVISHEEIKDYHETEDVQHHGDFTDQTYVNAVRDGVENLEAVLCSPESQRQLVPLGPKVVANRSKSRKTIDSEDTQKRCLAQEDGTLVTESRRTTEHELIVDDELPDPPANGASDDLGLQLQVGEQVTTTAANQRFFRQRDEQHVDVLANGRLQSTEMRYAAETTQMDKDGPTDLERPGDWDSLSDRMRKLRRSQQQQQKEVALLADRKDALTKRPLDFDREEETRKGETMKWLESHFGSESTASNDSRDDEADAEVEPTKKSYFNVTIKSQSHAQSHLATQQHSHPQHISHGHHPQTLPRSAERERERERERERERERERERERDRDRHPLAMTASASQERKAPANSAGGRSKYFQGISNWSERKDPGPPVNHFSSQAFRDDLQETIRRNGLKKKVSGPGSSQGSALAQETVVQPKDSYVSREDILQQKRQSLSSQFLARSMRGSRDALDDLEAIPGPGPGPSMISPRAEEPSHKRVAYGHRGNNGTHINGHALNGVAPTLVNGRGKSYEPPAPPPAAVPPLEFGGGGSQLGQNPRPTVPQRRRAIEKKLGEHSHTHSHSHSHSSHTSHSAHLPVKSQAPMPSQLNQLEPPPDYSPPPRSRSRSSSPQVDYLMTREMPASTMTLSRKQQQRTRFAPTSSYPPATGGTGNLRPPGATSVSTSNLSAMSGGVSTSKSSRMGQVIGNSLRKLVSKIRSASAERKFRMKSAASKSREQSPSPGQDPRGVGPPVTTYQQYNVIDGHIGSHDSEDSNSDNQRRRERERERERERERERERDPLKQESQSRQNFKRAESADPQLQHLEQAISPRQRYYLGEDPYSSTLYGKENHYERRPRQRNMERTDERMERLERLEREDDYYESRAPPPVTAAHTLGRYQKHGQRFSGSTPNLHQQQQDYRSAQTLPRKLHEQRTQRFGNAMEKQPAPGRGSYLSASGQQQQSRGIPHNQNQQNQQNPNPSPSINGNPNPMQAQQGPAKPARTYAKVLNRSKSFNVHGMNGSNDPSPIYIEKLTRNNYQQRQEPSFGYGLGQGPNANYKSNPHLFSGKDNSLKSGLKSPSIVNLISRSQKDLTKIAGNDEDDVGYPEQDKKQLYLRGLHQQAPDLYRVIHGDEDYGSRKYPLQAKYSLDSRSPPSVELNKDTASIVRRSSEVDHQQSHHHNQQHHQHHIQSHQQQNLRRGSGATIIELRHRK
Protein: Light-regulated zinc finger protein 1 (F4IBS4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKIQCNVCEAAEATVLCCADEAALCWACDEKIHAANKLAGKHQRVPLSASASSIPKCDICQEASGFFFCLQDRALLCRKCDVAIHTVNPHVSAHQRFLLTGIKVGLESIDTGPSTKSSPTNDDKTMETKPFVQSIPEPQKMAFDHHHHQQQQEQQEGVIPGTKVNDQTSTKLPLVSSGSTTGSIPQWQIEEIFGLTDFDQSYEYMENNGSSKTDVLKMKLLDSACLGKKLEKADTSRRGDSDSSSMMRSAEEDGEDNNNCLGGETSWAVPQIQSPPTASGLNWPKHFHHHSVFVPDITSSTPYTGSSPNQRVGKRRRRF
Protein: Rho guanine nucleotide exchange factor 15 (Ephexin-5) (E5) (Vsm-RhoGEF) (O94989)
Organism: Homo sapiens (Human)
Function: Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
Subcellular location: Cell projection, dendrite {ECO:0000250}. Note=Expressed exclusively in dendrites of the developing hippocampus. {ECO:0000250}.
Interaction partners:
- Ubiquitin-protein ligase E3A
- Transforming protein RhoA
- Ephrin type-A receptor 4
- Proto-oncogene DBL
- Cell division control protein 42 homolog
Sequence:
MSAQSLPAATPPTQKPPRIIRPRPPSRSRAAQSPGPPHNGSSPQELPRNSNDAPTPMCTPIFWEPPAASLKPPALLPPSASRASLDSQTSPDSPSSTPTPSPVSRRSASPEPAPRSPVPPPKPSGSPCTPLLPMAGVLAQNGSASAPGTVRRLAGRFEGGAEGRAQDADAPEPGLQARADVNGEREAPLTGSGSQENGAPDAGLACPPCCPCVCHTTRPGLELRWVPVGGYEEVPRVPRRASPLRTSRSRPHPPSIGHPAVVLTSYRSTAERKLLPLLKPPKPTRVRQDATIFGDPPQPDLDLLSEDGIQTGDSPDEAPQNTPPATVEGREEEGLEVLKEQNWELPLQDEPLYQTYRAAVLSEELWGVGEDGSPSPANAGDAPTFPRPPGPRNTLWQELPAVQASGLLDTLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQGVSERFLATLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILRQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLEFQGELTELGCRRGGVLFASRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQASSLSDMQRWLGAFPTPGPLPCSPDTIYEDCDCSQELCSESSAPAKTEGRSLESRAAPKHLHKTPEGWLKGLPGAFPAQLVCEVTGEHERRRHLRQNQRLLEAVGSSSGTPNAPPP
Protein: Voltage-dependent L-type calcium channel subunit alpha (A0A8I5ZMH8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}.
Interaction partners:
Sequence:
LSEAETKPLNTTPEPSPANGTGPGPEWGLCPGPPTVGTDTSGASGLGTPRRRTQHNKHKTVVVASAQRSPRALFCLTLTNPIRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRSCTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLRGYLDWITQAEELDLHDPSVDGNLASLAEEGRAGHRPQLSELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSITDTPGDEDEEEGTMASCTLCLNKIMKTKVCRHFRRANRGLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQTQEYANKVLLCLFTVEMLLKLYGLGPSVYVASFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLASGDAGAVPGGENEDTEGTKSEGAAPGMEEEEEEEEEEEEENGAGHVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKACHTLIHHHVFTSLILVFIILSSVSLAAEDPIRAHSFRNHILGYFDYAFTSIFTVEILLKMTVFGAFLHQGSFCRSWFNLLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTLKECKGSFLIYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDAHAEDEGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTVEMVLKIIAFKPKHYFADAWNTFDALIVVGSVVDIAVTEVNNGGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGEEFTCGSNFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNVPLNSDGTVTFNATLFALVRTSLRIKTEGNLDQANQELRMVIKKIWKRIKQKLLDEVIPPPDEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLGADAPTSTSSVLQAGLRSLQDLGPEIRQALTYDTEEEEEEEEAAGQEAEEEEAENNPETYKDSIDSQPQAQWNSRISVSLPVKEKLPDSLSTGPSDDDGVAPNSRQPSGLQAGSQPHRRSSGVFMFTIPEEGSTQLKGVQGQDNQNEEQEVPDWTPNLDEQAGMPSNPVLLPPHWSQQHVNGHHVPRRRLLPPTPAGRKPSFTIQCLQRQGSCEDLPIPGTYHRGRTSGPGRAQGSWAAPPQKGRLLYAPLLLVEESTVGEGYLGKLGGPLRTFTCLQVPGAPSDPSHRKRGSADSLVEAVLISEGLGLFAQDPRFVALAKQEIADACHLTLDEMDSAASDLLAQRTTSLYSDEESILSRFDEEDLGDEMACVHAL
Protein: GTP-binding protein (Q7ZVA2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTLNTQKEGKEPLRRRASTPIPSSRQAGRGDRDPSTDPYHPPLAQSASYHPGDKSIHSRANWSSDSESDSSGSECLYRVVLLGDHGVGKSSLANIFAGIQEKDAHKHIGEDAYERTLMVDGEDTTLVVMDPWETDKQEDDEKFLQDYCMQVGNAYIIVYSITDRSSFESASELRIQLRRIRQAENIPIILVGNKSDLVRSREVAVEEGRACAVMFDCKFIETSASLHHNVHELFEGTVRQIRLRRDSKEINERRRSVYKRKESITKKARRFLDRLVAKNNKKMALKVRSKSCHDLAVL
Protein: Calcium-transporting ATPase 1, endoplasmic reticulum-type (EC 7.2.2.10) (P92939)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the endoplasmic reticulum lumen. Also regulates manganese ion homeostasis by pumping it into endomembrane compartments. Can also transport zinc.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- Vacuolar cation/proton exchanger 2
- Metal tolerance protein 11
- ECA1 gametogenesis related family protein
- ECA1 gametogenesis related family protein
- Vacuolar cation/proton exchanger 4
- F-box associated ubiquitination effector family protein
- Vacuolar cation/proton exchanger 1
- ECA1 gametogenesis family protein
- Egg cell-secreted-like protein
- Putative F-box protein At1g59675
Sequence:
MGKGSEDLVKKESLNSTPVNSDTFPAWAKDVAECEEHFVVSREKGLSSDEVLKRHQIYGLNELEKPEGTSIFKLILEQFNDTLVRILLAAAVISFVLAFFDGDEGGEMGITAFVEPLVIFLILIVNAIVGIWQETNAEKALEALKEIQSQQATVMRDGTKVSSLPAKELVPGDIVELRVGDKVPADMRVVALISSTLRVEQGSLTGESEAVSKTTKHVDENADIQGKKCMVFAGTTVVNGNCICLVTDTGMNTEIGRVHSQIQEAAQHEEDTPLKKKLNEFGEVLTMIIGLICALVWLINVKYFLSWEYVDGWPRNFKFSFEKCTYYFEIAVALAVAAIPEGLPAVITTCLALGTRKMAQKNALVRKLPSVETLGCTTVICSDKTGTLTTNQMAVSKLVAMGSRIGTLRSFNVEGTSFDPRDGKIEDWPMGRMDANLQMIAKIAAICNDANVEQSDQQFVSRGMPTEAALKVLVEKMGFPEGLNEASSDGDVLRCCRLWSELEQRIATLEFDRDRKSMGVMVDSSSGNKLLLVKGAVENVLERSTHIQLLDGSKRELDQYSRDLILQSLRDMSLSALRCLGFAYSDVPSDFATYDGSEDHPAHQQLLNPSNYSSIESNLIFVGFVGLRDPPRKEVRQAIADCRTAGIRVMVITGDNKSTAEAICREIGVFEADEDISSRSLTGIEFMDVQDQKNHLRQTGGLLFSRAEPKHKQEIVRLLKEDGEVVAMTGDGVNDAPALKLADIGVAMGISGTEVAKEASDMVLADDNFSTIVAAVGEGRSIYNNMKAFIRYMISSNIGEVASIFLTAALGIPEGMIPVQLLWVNLVTDGPPATALGFNPPDKDIMKKPPRRSDDSLITAWILFRYMVIGLYVGVATVGVFIIWYTHSSFMGIDLSQDGHSLVSYSQLAHWGQCSSWEGFKVSPFTAGSQTFSFDSNPCDYFQQGKIKASTLSLSVLVAIEMFNSLNALSEDGSLVTMPPWVNPWLLLAMAVSFGLHFVILYVPFLAQVFGIVPLSLNEWLLVLAVSLPVILIDEVLKFVGRCTSGYRYSPRTLSTKQKEE
Protein: Probable drug/proton antiporter YHK8 (P38776)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable drug/proton antiporter.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Quinidine resistance protein 2
Sequence:
MVAEFQIASAQSSALTSTEEEHCSINSDKAAKLDLELTSERKNDGKQSHEVTFNEDIADPEDIARHMSTARRYYISSLITFTSMVITMISSSWTLPSTHIIEHFHISHEVSTLGITLYVFGLGIGPLFLSPLSELYGRRITFLYALTLSIIWQCLTIWSKTITGVMFGRFLSGFFGSAFLSVAGGAIADIFDKDQIGIPMAIYTTSAFLGPSLGPIIGGALYHQSYKWTFITLLITSGCCLVMIIFTIPETYKPMLLIRKAKRLRKEKNDQRYYAVLEVTREQTSLLSAIFLSTKRPFGLLLRDRMMGVLCFYTGLELAIIYLYFVAFPYVFKKLYNFGPMEIACSYIGIMVGMILSAPTCLLFQKTFEWRVKRNNGVKTPEMRFEPLFYGAFLTPVGLFIFAFTCYKHVHWIAPIIGSAIFGSGVYFVFTGVFAYTVDAYRRYAASGMACNTFVRCIMAGVFPLFGLQMYKSMGVNWAGFLLAMVTVAMIPVPFLFTKYGARLRAKSPYAWDD
Protein: Uncharacterized protein, isoform G (M9NCS7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNKVEFKNKNKDQGPCARVRKIRPINMGGNVEQRPWTPTVRIGKIAAETTNPGPATVQLPTLIGSKVPDSKKKAAPSYSFGHKLGGKYDTSGPGPAQYNVTGMRAKGRDYPRAATLQSRPKELTRFSNPGPGEYDVVPAAKAVIDATPKYTFGQRPVALKTFQIPAPNSYCPEKVTQSKKNAPRYTFGRRTKIEHDQGTPAPGAYCPEKVKLNKTPEFSFGIKHHEQRPDYTPAPGTYKPEQVVLEHIPAYSFGLKTKHIQVSDTPAPGAYSPEKSRLHSAPAYSIAGKASQDVVDCTPAPGAYEPEKCVLSRTPAFSFGHRAELAKSSDTPAPGTYNPEKVRLDHTPAFTLSGRPETRSVSETPAPGSYAPEKYRNDRTPAFTFGGKHEQRLESSTPAPGDYCPEKVRHDHNPAFSFAGRHDLHKPSDTPAPGAYDTEKVRQDHNPAFSFAGRHDLHKPSETPAPGAYSPEKVRQDHNPAFSMAGKHSQKVTSDSPAPGDYCPEKVRLDHTPAYSFGVKSDPKVENNTPAPGDYHPEKVRQDHNPAYSFAGRHDLQKPDNTPAPGAYFPEKVRLDHNPAFSMAGKYDAKVTNDTPAPGDYSPEKVRQDTNPAYSFAGRHDLHKPSETPAPGAYSPEKVRLDHNPAFTMAGKHDQKILNGTPAPGDYSPEKCRLDHTPAYSFGGKNDPKVENNTPAPGDYHPEKVRLDHNPAYSFAGRHDLQKPSDTPAPGAYSPEKVRQDHNPAFSMAGKPVEKLTNGTPAPGDYSPEKVRLNHTPAYTFGGKNDPKVENNTPAPGDYHPEKVRQDHNPAFSFAGRHDLHKPNDTPAPGAYCPEKVRQDHNPAFSMAGKYTQKVANDTPAPGDYSPEKVRLDHTPAYTFGGKNDPKVESNTPAPGDYHPEKVRQDHNPAFSFAGRHNLQKPSDTPAPGAYSPEKVRQDHNPAFTMAGKHDPKVSNDTPAPGDYSPEKVRLDYTPSFTFAGKNNPKVENDTPAPGDYHPEKVRQDHNPAFSFAGRHDLHKPSDTPAPGAYSPEKVRQDHNPAFSMAGKYIEKITNGTPAPGDYCPEKVRLDHTPAFTFGGKNDPKVENNTPAPGDYHPEKVRQDHVPAFSFAGRHDLHKPNETPAPGAYSPEKVRQDHNPAFTMAGKHDPKVTHDTPAPGDYHPEKVRLDHNPAFSFAGRHDLHKPSETPAPGDYFPEKVRQDFNPAFTFAGKHDPRSLSESPAPGDYSPEKVRLDHAPAFSFGGKHDPKTEHLHPAPCDYAPEKVRLDHTPAYTIAGRPAADHVSQTPAPCDYHPEQCQVDSTPAFTFGMRLGRERISDTPAPSAYEPEKHSLHSTPAYSFGTKSDIRVTTDAPAPGHYHPEQCKLDSSPAYSFGLKTVPTASLPEPRGAYIEDRIVQRRERRLASPVRNNAECTTTTTNHTNNNAGSSTTTTTTTTTTTKTFINGVEQPELQKKETTKQVNGTHKELKSAPQAPLSNGNIVSNGNHSKMVSTTTRIQEVAHGQKESGNLKVVASGKSDASATKAAAVSHQTVVQADGAIVTSGQSSRMQTVKYAVEASSVQEKIISS
Protein: Propanediol dehydratase large subunit (EC 4.2.1.28) (Diol dehydratase large subunit) (DDH large subunit) (Propanediol utilization protein PduC) (P37450)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol (1,2-PD) to propionaldehyde. Required for S.typhimurium growth on 1,2-PD as the sole carbon and energy source (Probable). This subunit is directly targeted to the BMC (By similarity).
Subcellular location: Bacterial microcompartment {ECO:0000269|PubMed:10498708, ECO:0000269|PubMed:11844753, ECO:0000269|PubMed:12923081, ECO:0000269|PubMed:21821773, ECO:0000269|PubMed:27063436}. Note=Probably located inside the BMC shell. {ECO:0000305|PubMed:10498708}.
Interaction partners:
- Propanediol dehydratase medium subunit
- Propanediol dehydratase small subunit
- Propanal dehydrogenase
- Bacterial microcompartment shell protein PduB
- Propanediol dehydratase-reactivating factor small subunit
- 1-propanol dehydrogenase PduQ
- Propanediol dehydratase-reactivating factor large subunit
- Corrinoid adenosyltransferase PduO
- Bacterial microcompartment shell vertex protein PduN
- Propanediol utilization protein PduV
Sequence:
MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSEFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID