wanglab/gogpt-training-data huggingface dataset:
Protein: Transmembrane protein (Q381I5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNPTDLREGAQPLLPAFPPPPGHSSSGGGGIPDSGLQFHGGTRPLWATATPAVATAPVSAAGVPPSQVGFNTGLPSEPQGAAYAGREGYANAAIRASADFWKSEQARRVAMEQATGSGCSSLPGEFRGPERAEFPSEELEFHTGSPKYVLPVSLLLAVGLFGAIPLMSSFAFAVLLTGCIVTYVVDYAGYRLGGVFAIIATTLCFGFALFLSNLRASITFLGPLCMILTVQGLLTTTAMAAFLHFHWLQVGYPELVCLMERSVLGVTPMLVLPSLLSSTTAFVGSRHAPAWFLLSMCAIHCYFYRPLESSFVLRRRVTRGEQADLGQSPKRRGKADDDGNRSSGIAGVGEEAGESWMQINGKPEAVVFTVLLLVLPATLYVAFQRDLYEAWLSNIVNVVGMVCVQILYLFWKPERSLWFLLSNKQNSREFFAHDSFGLCVTIYRYRSCMYALGALILPNWCVYRLLNSRYRFLFDGVAPPINGILLSVALYAALLAAYMTKKLLDADKEGRSVLTDRHMKERMVAIVAAAVSAVFVGFVVGLPGPLMFNLVICLCSFNLFLIDRGNAGLMFIFAFFSSLLLAWWMSRTFSFVILRLHVFGESRTIPSPALAGNILSSYFVGCMSFPHAFTGFKFLYALTLFLQSLNVVVVEHILYSQKEDGVYPAVLVLFTSVVGVLLVSRLHRNGVLGAAGASLVASSYIAKLFKFLVEVTGSYYVEDAEMESSGPLFAVEITTMWWAALLCGFVAMLFELEKVSQMGNKTIVATVVLFAFSAMLMVASTVRNFQRATYEFLTKSQITEGEAAYVFVGMSCIVFGALTYPFSARHLGVGPIMRHLNSVARGALGLGIIVLASQAIHLESAKDEEEFGTEELGYSKQCVLAGMLLVAAGRYLPMASLPMAISVIYWFVATFFLVAGLGTYLLPTPSVLLLISLGVFVYFTFVTLDVAHYREKRMQYLWMLSTVAVCFAVFSVALMGRGGMEESDTSDVLLIWETHVVGLRRLLSVVSVTGLFTAILLRFRLGGEALLPGAVPITSELMEHIGVVVNYNVILSVTCLTVLNMWNHDYEPGLHVVTSLLLLLLVKDDTLFLELDRENYRYFPPLAYALGLLWGCLIHDAYRAGGSRTSSVAAVLREVLCALPLAPSHISLLTLVYASKKAARVSVRPAVAFVLVGIMTLLFSSQKAVQWMAVVGICGHSARLLEAQLMGFFSDVR
Protein: Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (JKT41-binding protein) (Q9Z130)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional regulator. Promotes transcription repression (By similarity). Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences (By similarity). Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs (By similarity). Binds both to nuclear and cytoplasmic poly(A) mRNAs (By similarity). Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers (By similarity). Binds to the 5'-ACUAGC-3' RNA consensus sequence (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:10717477, ECO:0000269|PubMed:15190078}. Cytoplasm {ECO:0000250|UniProtKB:O14979}. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner. {ECO:0000250|UniProtKB:O14979}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein H
- Serine and arginine-rich splicing factor 11
- Heterogeneous nuclear ribonucleoprotein M
- Serine/arginine-rich splicing factor 2
- ATP-dependent RNA helicase DHX15
- Heterogeneous nuclear ribonucleoproteins A2/B1
Sequence:
MEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
Protein: Taste receptor type 2 (Q496D7)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004424}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004424}.
Interaction partners:
Sequence:
MMSFLHIVFSILVVVAFILGNFANGFIALINFIAWVKRQKISSADQIIAALAVSRVGLLWVILLHWYSTVLNPTSSNLKVIIFISNAWAVTNHFSIWLATSLSIFYLLKIVNFSRLIFHHLKRKAKSVVLVIVLGSLFFLICQLVMKNTYINVWTEECEGNVTWKIKLRNAMHLSNLTVAMLANLIPFTLTLISFLLLIYSLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLVLLAIYFLCLIISFWNSKMLPKEIVLMLCQAFGIIYPSFHSFILIWGNKTLKQTFLSVLWQVTCWAKGQNQSTP
Protein: Nrap protein domain-containing protein (Q388S9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|RuleBase:RU364032}.
Interaction partners:
- KRR1 small subunit processome component
- U3 small nuclear ribonucleoprotein
- Bms1-type G domain-containing protein
- 40S ribosomal protein S13, putative
- U3 small nucleolar RNA-associated protein 6 N-terminal domain-containing protein
- U3 small nucleolar ribonucleoprotein protein IMP3, putative
- HEAT repeat-containing protein 1
- Uncharacterized protein
- BING4 C-terminal domain-containing protein
- CCAAT-binding factor domain-containing protein
Sequence:
MLPTPYHLQWSEELIRHVELRLRQLHACLNEFYQKNNYSTASCTGAQALDSVSEPIGQNATDPVQAAGSFLLRTCVHSTPFYETQLKRGVGADLVLTVPEEVCSLKDVQIGLYLDRRHEFLLKVERFLRKYAKRMVQEETGKNGGASEGGRNGDGSSDVKEDGRQRRKYIRWDIQRVPFGDCWVNEEKYIIRIVFLRDSSNATRREVFHVDLHFQPISVSGRIASVAAIRKHPYYSHLVLEDALMTTHLRKLHNLFSNSNSLQRAAVFLNCWAHHTGIMARTSGHPEALSGFHLSAVILRLVEEGVVSPSMSEENVVRAVWVYLSRGLTLTESYATLNNDGEGKNHEEVAGALSLGNRSDVAVLRLEGETMNLLFRTSTSFLKQVVKKAADDAMQYQRSSEVLLKTPFQPLQLSMDVCLVVSGLEAHFAETNSAGNGKTGGAAYLRPEEVTQKLYLVVCEALGVRASYVTMWRRSADAAHVAVRLATEAEGRNRLTRGPPLEDTEAVSRFNNFWGNDITSTRQFPDGGIYRCVLWTFDHDAASHAIVLPATTVVRRVVQFALEKHIGASARVAVLLNGLEGVLAERVGAEWRDTAPLVEKSLLDACRAVETMVVDIPRTALPCKITSLDIVSASERHTATFPVRPHIALTYTTDDITQPCFAGLSVAPTIEPVHGVLTIDDRNKIPDTVEAIATMKGAICAQLSKVLQEQYGDDEGKVDGGTSIEGKEGKLKKEREEHISRQGEGETCGKETEKLHIRSSCTAHSVDIIFKGYLFRLYIAHYREVSLLRALGRESEASTIERKLFWSAQHAKFLRTISFGHSSYATATRIASRWMSAMLLYEFIVPEAVELLVANAYLGAVPPKTPASGFLRFLQLLACHDWKEPLVLPYSMDSKEQAEAAALVRSMGEERGMFIATPYAPLESPFTVHTPRPLIVHRVVQLAKAALSVLIDLVSENDSPSHLEAAVFTPNPSDFDFQMVLHPCLLLQTDRLIAPPSIEKVKAAGANGVGSGISGAGTVAGESTDSPATARVWRLDELEAAKSRIYISELVEREPAAHVVRSVRAATRDRSMVFYDCLAPRSISVITITSHAPRNHCSKLHDDILRISRGALLPTALRSLTSEEETATNEVMETKGVSSRVHNVMDKDAIVAAARGALRRKRSNINEGKEGKSSKRPRREGSKTKLEVRQSQHDSRKSSADKGKKRSAVAEQDGKSKGTNGETNKKTEKVAKRKVK
Protein: Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2 (AtMPF2) [Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.1.2.3) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)] (Q9ZPI5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in peroxisomal fatty acid beta-oxidation during seed germination. Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18). Possesses 3-hydroxy-3-phenylpropionyl-CoA dehydrogenase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of substituted hydroxybenzoylated choline esters, which are BA-containing secondary metabolites. Fatty acid beta-oxidation pathway in peroxisomes regulates gene silencing, histone acetylation and DNA methylation.
Subcellular location: Glyoxysome {ECO:0000305}. Peroxisome {ECO:0000269|PubMed:17951448}.
Interaction partners:
- 3-ketoacyl-CoA thiolase 2, peroxisomal
- Peroxisomal acyl-coenzyme A oxidase 1
- 3-ketoacyl-CoA thiolase 5, peroxisomal
- 3-ketoacyl-CoA thiolase 1, peroxisomal
- Acyl-coenzyme A oxidase 2, peroxisomal
- Putative peroxisomal acyl-coenzyme A oxidase 1.2
- Acyl-coenzyme A oxidase 4, peroxisomal
- Acyl-coenzyme A oxidase 3, peroxisomal
- Putative acyl-coenzyme A oxidase 3.2, peroxisomal
- Putative acyl-coenzyme A oxidase At3g06690
Sequence:
MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQASSRL
Protein: Transmembrane emp24 domain-containing protein p24delta5 (Atp24) (p24 family protein delta1c) (p24delta1c) (p24 family protein delta5) (p24delta5) (Q8RWM6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side (By similarity). Interacts with p24beta2 at endoplasmic reticulum export sites for endoplasmic reticulum exit and coupled transport to the Golgi apparatus. Once in the Golgi, interacts very efficiently with the COPI machinery for retrograde transport back to the endoplasmic reticulum.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18266912, ECO:0000269|PubMed:22132757, ECO:0000269|PubMed:22577184}; Single-pass type I membrane protein {ECO:0000269|PubMed:18266912, ECO:0000269|PubMed:22132757, ECO:0000269|PubMed:22577184}. Note=Cycles between the endoplasmic reticulum and Golgi via COPI and COPII dependent pathways. Mainly located in endoplasmic reticulum.
Interaction partners:
- Transmembrane emp24 domain-containing protein p24beta2
- ER lumen protein-retaining receptor A
- Coatomer subunit delta
- Transmembrane emp24 domain-containing protein p24beta3
- Coatomer subunit gamma
- Coatomer subunit alpha-2
- ADP-ribosylation factor 2-B
- Protein transport protein SEC31 homolog A
- Coatomer subunit alpha-1
- RINT1-like protein MAG2L
Sequence:
MAINRIAHGSLFLTVVLFFLTVNYGEAIWLTIPTTGGTKCVSEEIQSNVVVLADYYVVDEHNPENTPAVSSKVTSPYGNNLHHQENVTHGQFAFTTQEAGNYLACFWIDSSHHLANPITLGVDWKMGIAAKDWDSVAKKEKIEGVELQLRRLEGLVLSIRENLNYIKDREAEMREVSETTNSRVAWFSIMSLGVCVVVVGSQILYLKRYFHKKKLI
Protein: Polymerase/histidinol phosphatase N-terminal domain-containing protein (P96221)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible membrane protein
- Probable endonuclease 4
- Peptide deformylase
- Endoribonuclease YbeY
Sequence:
MDPVTALRQIAYYKDRNRHDPRRVMAYRNAADIIEGLDDAARQRHGQANSWQSLAGIGPKTAKVIAQAWSGREPDLLAELRADAEDLGGGAIRAALRGDLHLHSNWSDGSAPIEEMMATAAALGHQYCALTDHSPRLTIANGLSPDRLRKQLDVIDELREKFAPLRILTGIEVDILEDGSLDQEPEMLDRLDIVVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIRPESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLHLARDIGCVFSIDTDAHAPGQLDFLGYGAQRALDAEVPADRIVNTWPADTLLAWTGSH
Protein: Laminin subunit gamma-3 (Laminin-12 subunit gamma) (Laminin-14 subunit gamma) (Laminin-15 subunit gamma) (Q9R0B6)
Organism: Mus musculus (Mouse)
Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane.
Interaction partners:
- Laminin subunit beta-1
- Laminin subunit alpha-2
- Laminin subunit beta-2
- Laminin subunit alpha-4
- CD44 antigen
- Laminin subunit alpha-3
- Laminin subunit beta-3
- Integrin, alpha 10
- Integrin alpha-5
- Integrin beta-8
Sequence:
MAVSRVLSLLATVASMALVIQETHFAAGADMGSCYDGVGRAQRCLPEFENAAFGRRAEASHTCGRPPEDFCPHVGAPGAGLQCQRCDDADPGRRHDASYLTDFHSPDDSTWWQSPSMAFGVQYPTSVNLTLSLGKAYEITYVRLKFHTSRPESFAIYKRTYASGPWEPYQYYSASCQKTYGRPEGHYLRPGEDERVAFCTSEFSDISPLNGGNVAFSTLEGRPSAYNFEESPVLQEWVTSTDILISLDRLNTFGDDIFKDPRVLQSYYYAVSDFSVGGRCKCNGHASECEPNAAGQLACRCQHNTTGVDCERCLPFFQDRPWARGTAEDANECLPCNCSGHSEECTFDRELYRSTGHGGHCQRCRDHTTGPHCERCEKNYYRWSPKTPCQPCDCHPAGSLSLQCDNSGVCPCKPTVTGWKCDRCLPGFHSLSEGGCRPCACNVAGSLGTCDPRSGNCPCKENVEGSLCDRCRPGTFNLQPHNPVGCSSCFCYGHSKVCSPAAGFQEHHIRSDFRHGAGGWQIRSMGVSKRPLQWSQSGLLLGLRGGEELSAPKKFLGDQRLSYGQPVILTLQVPPGGSPPPIQLRLEGAGLALSLRPSSLPSPQDTRQPRRVQLQFLLQETSEEAESPLPTFHFQRLLSNLTALSIWTSGQGPGHSGQVLLCEVQLTSAWPQRELAPPASWVETCLCPQGYTGQFCEFCALGYKREIPHGGPYANCIPCTCNQHGTCDPNTGICLCGHHTEGPSCERCMPGFYGNAFSGRADDCQPCPCPGQSACATIPESGDVVCTHCPPGQRGRRCESCEDGFFGDPLGLSGAPQPCRRCQCSGNVDLNAVGNCDPHSGHCLRCLYNTTGAHCEHCREGFYGSAVATRPVDKCAPCSCDLRGSVSEKTCNPVTGQCVCLPYVSGRDCSRCSPGFYDLQSGRGCQSCKCHPLGSLENKCHPKTGQCPCRPGVTGQACDRCQLGFFGFSIKGCRDCRCSPLGAASSQCHENSTCVCRPGFVGYKCDRCQDNFFLADGDTGCQECPTCYALVKEEAAKLKARLMLMEGWLQRSDCGSPWGPLDILQGEAPLGDVYQGHHLLQETRGTFLQQMVGLEDSVKATWEQLQVLRGHVHCAQAGAQKTCIQLAELEETLQSSEEEVLRAASALSFLASLQKGSSTPTNWSHLASEAQILARSHRDTATKIEATSERALLASNASYELLKLMEGRVASEAQQELEDRYQEVQAAQTALGIAVAEALPKAEKALATVKQVIGDAAPHLGLLVTPEAMNFQARGLSWKVKALEQKLEQKEPEVGQSVGALQVEAGRALEKMEPFMQLRNKTTAAFTRASSAVQAAKVTVIGAETLLADLEGMKLRSPLPKEQAALKKKAGSIRTRLLEDTKRKTKQAERMLGNAASLSSSTKKKSKEAELMSKDNAKLSRALLREGKQGYRHASRLASQTQATLRRASRLLLTSEAHKQELEEAKQVTSGLSTVERQIRESRISLEKDTKVLSELLVKLGSLGVHQAPAQTLNETQRALESLRLQLDSHGALHHKLRQLEEESARQELQIQSFEDDLAEIRADKHNLETILSSLPENCAS
Protein: Large ribosomal subunit protein uL5A (60S ribosomal protein L11-A) (P0CT77)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000250|UniProtKB:P0C0W9}.
Interaction partners:
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL18A
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein eS19A
- Large ribosomal subunit protein uL29
Sequence:
MAEKAQNPMKELRISKLVLNISLGESGDRLTRAAKVLEQLSGQTPVFSKARYTIRRFGIRRNEKIACHVTVRGPKAEEILERGLKVKEYELKKRNFSATGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMDRPGMRVARRKAQRGRVGYTHKINAEDTINWFKQKYDAVVLGK
Protein: WAP four-disulfide core domain protein 5 (Putative protease inhibitor WAP1) (p53-responsive gene 5 protein) (Q8TCV5)
Organism: Homo sapiens (Human)
Function: Putative acid-stable proteinase inhibitor.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- WAP four-disulfide core domain protein 12
- ETS-related transcription factor Elf-5
- Large ribosomal subunit protein mL64
- Keratinocyte differentiation-associated protein
Sequence:
MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARGTAPGCPGQANSDLGSVALHLSWGPTERVHDGRPGALPAGQHYLYQRWFQPSDNHWPADTSLQPIHPWFLLLGVKVHSLSSEEGLCITPVLCTTAIRASHPS
Protein: E3 ubiquitin-protein ligase rnf152 (EC 2.3.2.27) (RING finger protein 152) (RING-type E3 ubiquitin transferase rnf152) (Q58EC8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation.
Subcellular location: Lysosome membrane {ECO:0000250|UniProtKB:Q8N8N0}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q8N8N0}.
Interaction partners:
- Sine oculis-binding protein homolog B
- DnaJ
- Zinc finger protein 507
- AVL9 homolog
- E3 ubiquitin-protein ligase RNF182
- Golgi to ER traffic protein 4 homolog
- DnaJ homolog subfamily C member 11
Sequence:
MDSLSQSSRLECQICFNYFSQRRLPKLLHCQHTCCSVCLSQMRLSQREIRCPWCRCVTQIPIGLSVSHLPDDPEVLSVISVSQSSEHTPIFIHLPNNGCYLLPVSLDTDGTPLPGQPTCHVGPKSIGVFDVSDGQNHVLGHDGLGDGMEEEEVVVVKTTAWTGVCTVLLVAFILIFLLGIVLHNMSCVSKRFTIISCG
Protein: Basic leucine zipper transcriptional factor ATF-like 2 (B-ATF-2) (Q8R1H8)
Organism: Mus musculus (Mouse)
Function: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types. Possibly acts by interfering with AP-1 binding to CCN1 promoter (By similarity). Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Basic leucine zipper transcriptional factor ATF-like
- Basic leucine zipper transcriptional factor ATF-like 3
- Transcription factor Jun
Sequence:
MQLCGSSELLTETDLGESQKQLKKKQKNRVAAQRSRQKHTSKADALHQQHESLEKQNHALRKEIQALQTELAGWGRTLHLHERLCRVDCDPCPVLLPSGCPIQAKQPSGQPAPLGYNGCQEQLGLFQTPGSSPRAQHLSPGPCSHESPGLLPSLLPSLAFDPLMVRTPLAQLSPSPVLSASSPSGSSLLGSFSKLDPLIPSPQDQLAPPQPLRQEQPTSGRLASSDSPAALGPECSQNREHLPALPGSSTHWQKSSVAPSPQALMAFPLLSSAKVHF
Protein: Secreted protein (Q9VEL4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQVHRFFCGLLIYLFLICSAFSQDETKVPPTETTASPAASVAAEEAPKSSNPEASGSSKCKSNEILSENGCVDRENFLNKIMFRSWQDEGFGKAKARAGLVDGIECRDGEVRTPFGCSTPPYPPHRESDRVPVHHSSLYREQVVHSNYGSARSVHQEKVKIEKGKRQPYLGPPISGHNIPRKNYILPGRLLRSDRQCRPYESPGKDGQCHPKKGKTGNYKHTNHVYGLQLRHRHEAQG
Protein: Ring finger protein 38 (Q5XIX1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-conjugating enzyme E2 D2
- Polyubiquitin-C
- Transmembrane protein 169
Sequence:
MRPWEMTSNRQPPSVRPNQHHFSGERCNTPARNRRSPPVRRQRGRRERLSRHNSISQDENYHHLPYAQQQAIEEPRAFHPPNVSPRLLHPAAHPPQQNAVMVDIHDQLHQGTVPVSYTVTTVAPHGIPLCTGQHIPACSTQQVPGCSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQTQQSRSPLQRIENEVELLGEHLQVGSFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPVPPPTYHPSLLPYVLSMLPVPPTVGPTFSFELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPSNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKGNRTCPICRADASEVHRDSE
Protein: Serine/threonine-protein kinase 40 (EC 2.7.11.1) (Serine/threonine-protein kinase lyk4) (Q7TNL3)
Organism: Mus musculus (Mouse)
Function: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- E3 ubiquitin-protein ligase COP1
Sequence:
MKRRASDRGAGETSANAKALGTGIAGNNAKRAGPFVLGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGEQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEAVEDTESGRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSSSDSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHEARAWVPKRQFGSMPPVRRLGHDAQPMTSLDTAILAQRYLRK
Protein: Tubulin epsilon and delta complex protein 2 (Q7L2K0)
Organism: Homo sapiens (Human)
Function: Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability.
Subcellular location: Cell projection, cilium {ECO:0000250|UniProtKB:Q6GQV0}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q6GQV0}.
Interaction partners:
- Tubulin epsilon chain
- Tubulin epsilon and delta complex protein 1
Sequence:
MLPAGCSRRLVAELQGALDACAQRQLQLEQSLRVCRRLLHAWEPTGTRALKPPPGPETNGEDPLPACTPSPQDLKELEFLTQALEKAVRVRRGITKAGERDKAPSLKSRSIVTSSGTTASAPPHSPGQAGGHASDTRPTKGLRQTTVPAKGHPERRLLSVGDGTRVGMGARTPRPGAGLRDQQMAPSAAPQAPEAFTLKEKGHLLRLPAAFRKAASQNSSLWAQLSSTQTSDSTDAAAAKTQFLQNMQTASGGPQPRLSAVEVEAEAGRLRKACSLLRLRMREELSAAPMDWMQEYRCLLTLEGLQAMVGQCLHRLQELRAAVAEQPPRPCPVGRPPGASPSCGGRAEPAWSPQLLVYSSTQELQTLAALKLRVAVLDQQIHLEKVLMAELLPLVSAAQPQGPPWLALCRAVHSLLCEGGARVLTILRDEPAV
Protein: HIRA-interacting protein 5, putative (Q57V38)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Paraflagellar rod component, putative
Sequence:
MIKFTLRYFAVSSSTFYRLPRRMSTPTTRWAAFCALYSHRELLLCTICRGVCSGKSSQRSIVVEKNETPNPDCLRFYSMELSFLPPGRSLDLPDAQHAGKSPLAELLFSISGVQSVFLADEYITVGKVPHVDWGSLVPQIQECIVEFAESGVGVLSEEGEACFVDNNNDTDPEDDDDEVVLAVKELLSARIRPLLRADGGNVRYISMDDGTVFVLLEGACKSCPSSGVTLKNGIERMLMHWIPEVVEVQECTDEMASDLLAEKELRRKLKKDEVSASQSN
Protein: Protein-transporting protein (A0A1D8PSM6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Translocation protein SEC62
- Sec63 complex subunit
- Sec63 complex subunit
- Protein transport protein SEC61 subunit alpha
- Translocon subunit
- Endoplasmic reticulum chaperone BIP
- Protein transport protein Sec61 subunit beta
- Ssh1p
- Hsp70 family chaperone
- Signal recognition particle receptor subunit alpha homolog
Sequence:
MGSSEYNYDESGETWPFFVLALLSFILLPLTIKYISRVFTNTNPTKENQSIVGAIQENSETLKVPNLSEIKSFQSKQKSSKIFNKTLIFLLIGWSIVIYVAKYVTKEADLTVLFDPYTILDVSFTASEREIKSHYRKLSLKYHPDKLPKDLTEEQRSQAEQAYIRLTSAYKALTDEVTRENFLRYGHPDGEQPATHGIALPQFLVEGKYSSLVVVLYFMVIGILLPFIVGKWWSNVKSHTRKGLHVDTAANFVRKFTDRDPAKVITPDVILDYVLESEEIRQEFPNASHAELKDLVYRYLNRQFDSDPKVEKKKVDLIARLPFLINGLIDIAIVFRLHETIFAAEDLKKSIIQAVKPTGRYQELLQLPYVDPEIVSKQSIRKLGKLFAISKDEAKKALGIQSDEHLERALNVAQHIPTLRIIDAEIKVPGEEDGVVHPNSQGHISIKFLVKSPKLKSCPDIEDERLKDEETLEYMKNPLIVNEQQKKLPYSYAPYFPQPIRNSWSCYVIGQKENRLLEDSTNYVLENIDLNNLELSQEAWIKGTDVRIGTYKIQLPGAIGNVGNYYYRLVMKNNAYFGCDVDIPIDLEVTPVSIGKSLAGLKKKFDEEDESEDSESDSDISDPEEDSLAGAIAALRGSDLKKKKSSKDEVEEESEDEEVFTDINTDTEDEGDN
Protein: Scarecrow-like protein 29 (AtSCL29) (GRAS family protein 16) (AtGRAS-16) (Q9LRW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor involved in plant development.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Scarecrow-like protein 26
- Scarecrow-like protein 15
Sequence:
MLLEETEPPNQTLDHVLSWLEDSVSLSPLPGFDDSYLLHEFDGSQTWEWDQTQDPEHGFIQSYSQDLSAAYVGCEATNLEVVTEAPSIDLDLPPEIQQPNDQSRKRSHDGFLEAQQVKKSARSKRKAIKSSEKSSKDGNKEGRWAEKLLNPCALAITASNSSRVQHYLCVLSELASSSGDANRRLAAFGLRALQHHLSSSSVSSSFWPVFTFASAEVKMFQKTLLKFYEVSPWFALPNNMANSAILQILAQDPKDKKDLHIIDIGVSHGMQWPTLLEALSCRLEGPPPRVRITVISDLTADIPFSVGPPGYNYGSQLLGFARSLKINLQISVLDKLQLIDTSPHENLIVCAQFRLHHLKHSINDERGETLKAVRSLRPKGVVLCENNGECSSSADFAAGFSKKLEYVWKFLDSTSSGFKEENSEERKLMEGEATKVLMNAGDMNEGKEKWYERMREAGFFVEAFEEDAVDGAKSLLRKYDNNWEIRMEDGDTFAGLMWKGEAVSFCSLWK
Protein: Protocadherin alpha 5 (Q91Y15)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MVYFQRGSPGFRRLLISFVLLAAWEAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNPPKFSRPEQRLFILESRMPDSRFPVEGASDLDIGANAALSYKINPNEYFDLDVKRNEEETSVLQLVLKKPLDREETQEHRLLLIAIDGGKPELTGTVQLLIDVLDANDNAPEFDKSIYNVRLLENTPNGTLVIKLNASDADEGINKEILYFFSNLVLDDVKSKFTIDSSSGEIKVKGELDYEDCKVYEINIDAVDRSAFPLAGHCKIIVKLVDVNDNVPEMAITSIFLPIKEDAPLATVIALISVSDRDSGANGQVTCSLTPHIPFKLVSTFKNYYSLVLDRALDRETIANYDVVVTARDGGSPSLWATASVSVEVADVNDNVPAFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLGPQGSGGTIELLSRSVSSGHVVAKVRAVDADSGYNAWLSYELQPATGAVRSPFRVGLYTGEISTTRVLDEADMPRQRLLVLVKDHGEPPLTATATFLVSLVENSQTPKVSSRVLVGTSGSDSTLIDVNVYLIIAICAVSSLLVLTLLLYTAIRCSATPTDGACAPGKPVLVCSSAVGTWSYSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTENPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ