wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger protein 236 (Q9UL36)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger protein 407
Sequence:
MGLCGLLERCWLHHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQFDQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEAAGEWQALTHVF
Protein: Flagellar hook-associated protein 2 (HAP2) (Filament cap protein) (Flagellar cap protein) (P96786)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription.
Subcellular location: Secreted. Bacterial flagellum.
Interaction partners:
- Flagellar secretion chaperone FliS
- Flagellin B
- Flagellin B homolog
- Flagellar hook-associated protein 1
- Polar flagellin
- Flagellar motor switch protein FliN
- Flagellin A
- Flagellar M-ring protein
- Flagellar basal body rod protein FlgB
- Flagellar assembly protein FliH
Sequence:
MAIGSLSSLGLGSKVLNYDVIDKLKDADEKALIAPLDKKMEQNVEKQKALVEIKTLLSALKGPVKTLSDYSTYISRKSNVTGDALSASVGVGVPIQDIKVDVQNLAQGDINELGAKFSSRDDIFSQVDTTLKFYTQNKDYAVNIKAGMTLGDVAQSITDATNGEVMGIVMKTGGNDPYQLMVNTKNTGEDNRVYFGSHLQSTLTNKNALSLGVDGSGKSEVSLNLKGADGNMHEVPIMLELPESASIKQKNTAIQKAMEQALENDPNFKNLIANGDISIDTLHGGESLIINDRRGGNIEVKGSKAKELGFLQTTTQESDLLKSSRTIKEGKLEGVVSLNGQKLDLSALTKESNTSEENTDAIIQAINAKEGLSAFKNAEGKLVINSKTGMLTIKGEDALGKASLKDLGLNAGMVQSYEASQNTLFMSKNLQKASDSAFTYNGVSITRPTNEVNDVISGVNITLEQTTEPNKPAIISVSRDNQAIIDSLTEFVKAYNELIPKLDEDTRYDADTKIAGIFNGVGDIRAIRSSLNNVFSYSVHTDNGVESLMKYGLSLDDKGVMSLDEAKLSSALNSNPKATQDFFYGSDSKDMGGREIHQEGIFSKFNQVIANLIDGGNAKLKIYEDSLDRDAKSLTKDKENAQELLKTRYNIMAERFAAYDSQISKANQKFNSVQMMIDQAAAKKN
Protein: Serine/threonine-protein kinase AFC1 (EC 2.7.12.1) (P51566)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Activator of yeast transcription factor, STE12.
Interaction partners:
- PHD finger-like domain-containing protein 5B
- Small nuclear ribonucleoprotein E
- PHD finger-like domain-containing protein 5A
- Protein PHOX1
- Precursor of CEP6
- Serine/threonine-protein kinase-like protein At5g23170
- Probable serine/threonine-protein kinase PBL26
- Serine/threonine-protein kinase-like protein At1g28390
- Serine/arginine-rich splicing factor RSZ22A
- TOM1-like protein 6
Sequence:
MQSSVYRDKASSIAMILETQRNVEFPHRIVDKRPRKRPRLTWDAAPPLLPPPPPPTVFQPPLYYGPEFASGLVPNFVYPNMFYNGLPRQGSPPWRPDDKDGHYVFVVGDTLTPRYQILSKMGEGTFGQVLECFDNKNKEVVAIKVIRSINKYREAAMIEIDVLQRLTRHDVGGSRCVQIRNWFDYRNHICIVFEKLGPSLYDFLRKNSYRSFPIDLVRELGRQLLESVAYMHDLRLIHTDLKPENILLVSSEYIKIPDYKFLSRPTKDGSYFKNLPKSSAIKLIDFGSTTFEHQDHNYIVSTRHYRAPEVILGVGWNYPCDLWSIGCILVELCSGEALFQTHENLEHLAMMERVLGPLPPHMVLRADRRSEKYFRRGAKLDWPEGATSRDSLKAVWKLPRLPNLIMQHVDHSAGDLIDLLQGLLRYDPTERFKAREALNHPFFTRSREQSIPPFNPNPHPFLYNQKN
Protein: EP300-interacting inhibitor of differentiation 1 (21 kDa pRb-associated protein) (CREBBP/EP300 inhibitory protein 1) (E1A-like inhibitor of differentiation 1) (EID-1) (Q9Y6B2)
Organism: Homo sapiens (Human)
Function: Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
Subcellular location: Nucleus {ECO:0000269|PubMed:11223246}. Cytoplasm {ECO:0000269|PubMed:11223246}. Note=May shuttle between nucleus and cytoplasm. {ECO:0000250|UniProtKB:Q9DCR4, ECO:0000269|PubMed:11223246}.
Interaction partners:
- Retinoblastoma-associated protein
- Histone acetyltransferase p300
- Nuclear receptor subfamily 0 group B member 2
- Necdin
- EP300-interacting inhibitor of differentiation 3
- Retinoblastoma-like protein 1
- F-box only protein 21
- CREB-binding protein
- E3 ubiquitin-protein ligase Mdm2
Sequence:
MSEMAELSELYEESSDLQMDVMPGEGDLPQMEVGSGSRELSLRPSRSGAQQLEEEGPMEEEEAQPMAAPEGKRSLANGPNAGEQPGQVAGADFESEDEGEEFDDWEDDYDYPEEEQLSGAGYRVSAALEEADKMFLRTREPALDGGFQMHYEKTPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRE
Protein: Esculentin-1 (P84840)
Organism: Pelophylax saharicus (Sahara frog) (Rana saharica)
Function: Antimicrobial peptide (By similarity). Stimulates insulin release by BRIN-BD11 cells in vitro.
Subcellular location: Secreted {ECO:0000269|PubMed:16394170}.
Interaction partners:
Sequence:
GIFSKFGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
Protein: WD repeat-containing protein dyf-2 (Abnormal dye filling protein 2) (G5ECZ4)
Organism: Caenorhabditis elegans
Function: Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Moves along the ciliary axoneme and is involved in the assembly, localization and the movement of other intraflagellar transport (IFT) proteins along the cilia axoneme. May also associate with the BBSome complex in order to mediate ciliary transport. Regulates cilia biogenesis, morphology and sensitivity to environmental cues.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:16957054, ECO:0000269|PubMed:22922713}.
Interaction partners:
- WD_REPEATS_REGION domain-containing protein
- Intraflagellar transport protein 122 homolog
- Anaphase-promoting complex subunit 4-like WD40 domain-containing protein
- Intraflagellar transport protein 88 homolog
- Intraflagellar transport protein che-13
- TRAF3-interacting protein 1
- Intraflagellar transport protein osm-1
- Tetratricopeptide repeat protein 21 homolog
- CHE-2 protein
- Intraflagellar transport protein 56 homolog
Sequence:
MSLKVIPCTLTKNQEVFKCVSAQLQYRRGEEEHGSGPIIHRWRPNGHTVAVACANNTVIYYDKKGNVIDALNPTGKLIDIAWDKEGDVLAIAVANTGTIYLWDVNSRNTDTVESGATSSKELPTCLAWSPSTPTLVIGNNAGNIVVYNHRTSRRIAVMGKHQRSVTQITVTPEDYVISCSDDNTLSVTTLEGTTVSTTTTNGEPTNMDYGSVNGKGGSGVTMVSVVIGKKILMLAHYNALDEPVNLQFQEKYGNIHSYRWFNDGYILIGFDRGYIISISAHNNEIGSELVSFLEYRGYLASIAVSTSFNKLLTIGDNMVKVRDLDELTTVTMLTEIETEKNLSEIEVTEDGQLVAVSSQSGVLSIFVTKMPTLAASYNNSICYLTNLTQVTVVAEVEKKGSSTLELNIEPTVMGLGPLNLAVANNNTVFFYDYHTPAQMQAAQQLQSTQSAAEKPTIVAAEPINRVEYLSTVTNIQLNYMYAAVNFGSRLRLHRIRNSEDNVSIEFPEANRNATLYSYALTENFLIFTTSNNYIVYFSLSEWAIVSEYRHVVPVRSIFPHPTNVVCCCFDDRLEAMIYSAVDDEVFRLPSVGSSAHYKGAIWETFTIDKNTFAVFDSQNIYVFLLSKQHIQGESVIYVSATRLPHAYVPLSLNKGIVTCLMSNGKLSSVLLDSHKTESVISDKSETVIDDILTRSLLMHRWSTAWKICIHSNDGSHWNQFAMAALLDSDVGMAIKIFREIGDAAMVTALELIETIEEKNLLHAQIYTILSRYDDAEQLYLESSRPMEALNMRRDLLEWPKALVLAETMNPKEIPYLSKEYAQELELTGDHANSLANYEKGVMENPQNLPELQEHNEICQSGIARMAIKTGDLRRGVQLAKQLEGRVVKRDCAIILEQMKQYTEAAQLYEVGLFYDRAAAVCLKANAWAKVGELLDHVKSPKIHIQYGKIMEKEKKYKVAVKCYETGRDYDNQVRLLLDPLNDPDEAVRVVRESRSIEGAKLVAKFFVKLGDYNSAIQFLVMSQCVQEAFELAEKNNAVREYAKAIEQHGNISQALELAEYYNRVNDMFMAAKFYTQAGQYNNAINLLFKNGDDENCVALAVDCGIKSKDKTLNNKLVKFLLGEDGNVKDPAQLFRLYVGLGRTKDAAQTAVVVAQIHQAKGNYRIARDLLFQMHQQLREKMMRIPLDMNKSLMAIHSYIIVKALINRKETLLAARLLIRTCGEIQRFPTHVVPILTSSVVICTQANLKKSAHKFAAQLMTPEYRPKIHEKYKKKIEDIVRKGGNQKDLVEENTPCPICDDLMPAYAMSCDNCKSLVPYCILTGRHIVASDFSRCPHCEMPGFYSEFRKLSILNENCYMCGGDLKGAIPEDAKAYLEKMEQDYK
Protein: LD23102p (Zinc finger protein 30C) (Q9VL91)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Homeobox protein onecut
Sequence:
METESMAPSSSAAAAATKLLVEITTDGIPKLHCPVCNKALVSLAGYVKHVKKHQPPGGFECRHCDARFCHEEELTQHAKDEHGVTGAVAGQERKPFVCEKCGAEYKYQEAYRRHCRTKCGEEKLPREESRPMECKCCYTRFSSASNLSKHRRSRPDTCGQPEYDSPGSSDGMKKHKAFRKKDRNRDSDDEDTTSEESEDSDDDIPLASRLKTKLKQESQNSDSGDECPDFEPNNSEDDADASGFQLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLVEVAEEDVLELRGHQMEKPPGPRKRGRPPKEKIPVVKRKYRKRNAPRSPSPDDSSGTPKRVAKISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLNEAEMKEIFKDVDVHAKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDKYMTGHDSLKNHERNFHSKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASTHLVPHIVLQTMQAEARRME
Protein: CCDC81 HU domain-containing protein (Q38AJ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLSVQGAISNSSIMMECTASQDSYKREVFLLSELERVWDAVSTCIRHYVTEGRNVRVCNFGSFWFETRPVASDGRERYHARRIRFGIDGKFALRYNIDSIRVPQEPSKLEYVKVNMADVVAIARVPAQTAAMALREFFSYVGEGIFKKQVFKINFPGVATLVIKREKAVLIVEEGLRRDIFAVDSRKWPVAVREAAAGVVLDEQRRPVTRSSISRPSTGCSISSRMSNAPKPIEPRPAFMPAAPRNRLFAEIEKDPPRRLPLQHALQNKGDENCSPSPLYNENVGYVKESIFDALDPWEMETPSMEPEIELVEEVPEQLPSLRAYEEEAPHPVVCGRHSYHDHSSVRDLLYGSVTPRTDPMLCGRRRYINRDADQVATLLKDL
Protein: Neuronal regeneration-related protein (Neuronal protein 3.1) (Protein p311) (Q07475)
Organism: Mus musculus (Mouse)
Function: May have roles in cellular differentiation. Ectopic expression induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. May also have neural functions. Promotes axonal regeneration and augments motility of gliomas. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MVYYPELLVWVSQEPFAYKEMEGGLIKGRLPVPKEVNRKKMEETGAASLTPPGSREFTSPATSYLHPF
Protein: Candida glabrata strain CBS138 chromosome F complete sequence (Q6FU62)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Mitogen-activated protein kinase HOG1
- cAMP-dependent protein kinase
- non-specific serine/threonine protein kinase
- cAMP-dependent protein kinase
- Candida glabrata strain CBS138 chromosome I complete sequence
- Candida glabrata strain CBS138 chromosome M complete sequence
- Candida glabrata strain CBS138 chromosome F complete sequence
- Serine/threonine-protein kinase SCH9
- Transcription factor
- Candida glabrata strain CBS138 chromosome J complete sequence
Sequence:
MSVEQEPSSWSTQMENMFSLNIQDQNADVKYQSPLTPNYMSLDIYQGHKADIASNRGDANNDNGDDNEIASARGESNGRDTDNGINTNTTTTTNSSTVETNMTTTPATLDDFLMNFDSGATTATGKDKNPLVSDKPLGTHLQMNFVDSSSNGALPFSDQKGRRATIYNGFFESMHLDTMLDDYLSTELLLNEKPNGSNNNNDDDETVANERRHSEVVTGNTINLASARNSISHGVDFWNVDSHRKRGSNNGLHRDGHVNKSITRRATGGTEKHLTDDSLLLDSDISSHKIDNELSQILSDYNMNFKPGTEESPLKYNTADYYNFDGNSEDVSHSSAGQSHRPFMKNPHRASLPILSEATPPEYDLDIKKKQPDVSIFKDIPWESFNAEGADENDLSVANQNFYNPEIISSPKSPNDKFIKPTMILSDASLAEVEMMNNSIKSLNTSLDISIPPDVLNKDLKESWQNSQSRKSISGSSGRRRSSAALSMSNFNNNLHFNINASKSNPRRKSKPSISPNSSLLSSNIDRNNDIDKPFGCHLCSKAFKRSEHLKRHVRSVHSTDRPFSCHLCEKKFSRSDNLSQHIKTHKKSGSTSTTKE
Protein: Non-structural protein 1 (NS1) (NS1A) (P03496)
Organism: Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Function: Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated RIGI ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA.
Subcellular location: Host nucleus {ECO:0000255|HAMAP-Rule:MF_04066}. Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04066}. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm. {ECO:0000255|HAMAP-Rule:MF_04066}.
Interaction partners:
Sequence:
MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILKEESDEALKMTMASVPASRYLTDMTLEEMSRDWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLTPKQKREMAGTIRSEV
Protein: Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) (P32418)
Organism: Homo sapiens (Human)
Function: Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:11241183, ECO:0000269|PubMed:1374913, ECO:0000269|PubMed:1476165}; Multi-pass membrane protein {ECO:0000269|PubMed:23376057}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit gamma
- cAMP-dependent protein kinase catalytic subunit beta
- cGMP-dependent protein kinase 1
- cGMP-dependent protein kinase 2
- Sodium/calcium exchanger 2
- Sodium/calcium exchanger 3
- Ryanodine receptor 2
- Phospholamban
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Sequence:
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF
Protein: TraG3 (Q0PH56)
Organism: Neisseria gonorrhoeae
Interaction partners:
Sequence:
MMAVEYFTFPGNGEAVRAVFNGVATISGSTMMGGAMQAAALFGFLVTLAVAVFKLDLKDNFSYLFVVLFCWMGMMVPKTTVLITESGGYGYTGRQYTVGNVPVGLAYMGYFVSSFGQSITRKAEQVNHLPDDLNYSRTGMLFGTRLMENIREARIPDAQLTQDWALFMHQCSFFDMNLYHFYNVQDLAQSADILATLTHTNQALFTNVSQIASRRGNMLQYNGKSKTMTCNEAAKELKDRTRFYSKNYLPGYIADRVFAGLGTNSAGINRVNALVTLGNSSFQYLLDNARFDTLKNIEQAAMVEIIRQAGIINGQRNRNPAAVQQAFAQVQARNQYIAAQKTGSSMASWNLPLIRSAAEAILIGLFPFVMILAMLGGIMAFRLLSFYMMSMLWIQLWAPVASIINMIMTMNAKRLFSVEAANGVITPGTGDTLLMAAADAQAAAGAAMWLIPVIAGALAMGGRSLMNGMMGMTSSAKSTGEAAGSQVGSGNYSAGNMNYNNSNANKHSLNPVYTDPQMMTAQSAAGTSWRNMATGENRYQARGDSFGNVSSTSTVSMSDVYTQAADRSITAAKQYAASSVEQTTLGNTQTLAFGIQTVGQNGANYAVTNGMSSSTAKALDQILQSSKDIAQRNGMGNDVQTVSSIALDLGAQLAGGVTAGSKGAGPQASATVSGGASIRGEGKSSNKLSHDISETAKALESQGVSITRSMLENIGQSNAFTQALTDSSSLASQAQASYNKAHQASISEQQSYNEAQNYREAASRTAQSGATVSIDNAKAIREYADQNGLAYSQVYNNPSIVAAAAMNAAVAQASNLRQQAEGTRFDSTGPISPDDRPTNNVAAAYSSYKSGIDGQKSSTFATIQAQADGNGVNRNEARANIDGWQQKLEQGSKDAKNFNQKLFDKGMKKQEENTNKLHAQGEDTFKHVNTFVMGATQTFSSDKAYVQAQNKYGKTEGRREVVLVTIAQRSSPARYRLSRQWGKVIWLRK
Protein: Calcium-dependent protein kinase 12 (OsCDPK12) (OsCPK12) (EC 2.7.11.1) (Q7XSQ5)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity). Functions in signal transduction pathways that positively regulate responses to low-nitrogen (Ref.7). Functions in multiple signaling pathways, positively regulating salt tolerance and negatively modulating rice blast fungus resistance. May promote tolerance to salt stress by negatively regulating NADPH oxidase and positively regulating reactive oxygen species (ROS) scavengers.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Respiratory burst oxidase homolog protein B
- Os11g0537400 protein
- Os12g0541300 protein
- Os09g0438000 protein.
- Serine/threonine-protein phosphatase BSL1 homolog
- Os01g0734333 protein
- Os01g0734200 protein
- Os01g0835500 protein.
- Os04g0375500 protein
- Os01g0734466 protein
Sequence:
MGNCFTKTYEIPITSGTMRRPASTAERSKARGGDEPGTWRRPSFPRHGAPPHRPPTGSSSAAGALSRRASGGGGEMGPVLQRAMVSVRSLYQLDRKLGSGQFGTTYLCTERATGNRYACKSVSKRKLVRRTDVDDVRREITILQHLSGQPNIAEFRGAYEDNDHVHLVMEFCSGGELFDRITAKGSYSERQAAAVCRDILTVVHVCHFMGVIHRDLKPENFLLASADDDAPLKAIDFGLSVFIEEGKVYKDIVGSAYYVAPEVLQRNYGKEADIWSAGVILYILLCGTPPFWAETEKGIFDAILVNQVDFSTSPWPSISESAKDLIRQMLHRDPQKRITASQALEHRWLKEGGASDRPIDSAVLSRMKQFKAMNKLKQLALKVIAENLSPEEIKGLKQMFNNMDTDRSGTITVEELKVGLTKLGSRISEAEVQKLMEAVDVDKSGSIDYSEFLTAMINKHKLEKEEDLLRAFQHFDKDNSGYITRDELEQAMAEYGMGDEANIKQVLDEVDKDKDGRIDYEEFVEMMRKGIQT
Protein: Small ribosomal subunit protein bS1m (37S ribosomal protein mrp51, mitochondrial) (O42855)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:34634819}.
Interaction partners:
- Small ribosomal subunit protein uS13m
- Small ribosomal subunit protein uS4m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein mS47
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS8m
- Small ribosomal subunit protein bS18m
Sequence:
MSFAQILRGSRAMASPKCLPESNYSTSHLRFPRLQSITSKKNSRARGDWGLKRTLPKIKTRYICVRQQDSLYKQADFQSSAKFVRLVRNWFDAGFVRDPSEVALLQELLKETGLKDTRDINKVFSPSKQSDENDNFRRYGVSGGIQYSNVPLINSRVTPNCESNCSNIRRRLTAHIISSDASTAYYGLGGLILRLPRTVVFNRNRSSPLFSQEQRISYTVYKNGRLRLVPFSGPELETHLAYPSEDSEVESFFNRDIQLVAKRDSSLDAPVSYQRGIMKFFMAPSQTSNNEANSSEKDNLSNS
Protein: Acyl-CoA-binding domain-containing protein 5 (Q5T8D3)
Organism: Homo sapiens (Human)
Function: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
Subcellular location: Peroxisome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Vesicle-associated membrane protein-associated protein B/C
- Vesicle-associated membrane protein-associated protein A
- Peroxisomal membrane protein PEX16
- Peroxisomal biogenesis factor 3
- Peroxisomal membrane protein 11B
- Peroxisomal membrane protein PEX14
- ATP-binding cassette sub-family D member 1
- ATP-binding cassette sub-family D member 3
- Peroxisomal membrane protein PEX13
- Peroxisomal membrane protein 2
Sequence:
MFQFHAGSWESWCCCCLIPADRPWDRGQHWQLEMADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKSGRSSDITSVRLEKISKCLEDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVLQRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYLYYQRRRRKLN
Protein: Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase) (P30291)
Organism: Homo sapiens (Human)
Function: Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
Subcellular location: Nucleus {ECO:0000269|PubMed:8348613}.
Interaction partners:
- Cyclin-dependent kinase 1
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase Chk1
- G2/mitotic-specific cyclin-B1
- Cyclin-dependent kinase 2
- M-phase inducer phosphatase 1
- M-phase inducer phosphatase 3
- CDK5 and ABL1 enzyme substrate 1
- Wee1-like protein kinase 2
- M-phase inducer phosphatase 2
Sequence:
MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY