wanglab/gogpt-training-data huggingface dataset:
Protein: Stress-induced-phosphoprotein 1 (CeSTI1) (STI1) (Hsc70/Hsp90-organizing protein) (CeHop) (Hop) (O16259)
Organism: Caenorhabditis elegans
Function: Plays a role in gonad development. Up-regulates longevity and thermotolerance. Binds daf-21/hsp90 and inhibits its ATPase activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19467242}. Note=Detected in cytoplasm in early-stage embryos. {ECO:0000269|PubMed:19467242}.
Interaction partners:
- Heat shock protein 90
- Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein
- Heat shock protein 110
- Co-chaperone protein daf-41
- Histidine kinase/HSP90-like ATPase domain-containing protein
- Probable Hsp90 co-chaperone cdc37
- Heat shock protein 70
- DnaJ homolog subfamily B member 13
- Heat shock protein hsp-1
- peptidylprolyl isomerase
Sequence:
MTDAAIAEKDLGNAAYKQKDFEKAHVHYDKAIELDPSNITFYNNKAAVYFEEKKFAECVQFCEKAVEVGRETRADYKLIAKAMSRAGNAFQKQNDLSLAVQWFHRSLSEFRDPELVKKVKELEKQLKAAERLAYINPELAQEEKNKGNEYFKKGDYPTAMRHYNEAVKRDPENAILYSNRAACLTKLMEFQRALDDCDTCIRLDSKFIKGYIRKAACLVAMREWSKAQRAYEDALQVDPSNEEAREGVRNCLRSNDEDPEKAKERSLADPEVQEILRDPGMRMILEQMSNDPGAVREHLKNPEIFQKLMKLRDAGVIQMR
Protein: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) (P46978)
Organism: Mus musculus (Mouse)
Function: Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets (By similarity). STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient post-translational glycosylation and mediate glycosylation of sites that have been skipped by STT3A (By similarity).
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:12887896, ECO:0000269|PubMed:15781470}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:15781470}; Multi-pass membrane protein {ECO:0000269|PubMed:15781470}.
Interaction partners:
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
- Oligosaccharyltransferase complex subunit OSTC
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2
Sequence:
MTKLGFLRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSIYWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTETGRHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLDNRGLSRT
Protein: Rhodanese domain-containing protein (Q389B6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRRVVVDLRPKECYDEGHLEGAFSFPWEDIQNESCGLPPRETLLTAIVDERIDQGSVTAYLSRLQYAALEVRMLGQHEEMVRRPPEGFCWVPNPFLVSVLRFVEESSSGISFALDIGSGSGRDMVFLASRGWHVVGIENRRRLIWQGETLARKHDVSGRVAYLHSDIKEAYPVRSGSVDLVHVCRFLHRPSLSRLLELPRRGGHLVYSHFLEGCQHTKVGHPSSPAGFWRRGELRSLLEDAGYDVIHEEETTLPDTRPFLHILARRAV
Protein: Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C) (A1YPR0)
Organism: Homo sapiens (Human)
Function: May be a tumor suppressor gene.
Interaction partners:
Sequence:
MANDIDELIGIPFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFKKLFTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIVNVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQSPSKTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLRENLYPKANIPDRRPSLSPFAPDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKIKEEEKEELPPPPPPPFPNDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKPKASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRGRKPAAWRAASLLFGPGGPAPDKAAFVMPPALGEVGGHLGGAAVCLPGPSPAKHFLAAPKGALSLQELERQFEETQMKLFGRAQLEAERNAGGLLAFALAENVAAARPYFPLPDPWAAGLAGLPGLAGLNHVASMSEANN
Protein: Glycosyl hydrolase family protein (F4KE06)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cellulose synthase-like protein D5
- Probable glucuronokinase 2
- Glucuronokinase 1
- Aldo-keto reductase family 4 member C10
- Putative serine carboxypeptidase-like 30
Sequence:
MVVQAGYEPADHSGFQPYGPNLRLVHTVHSQLGLGSPDLRVCFRYIVSDCDSLGILYGSQHYTKTPEEAAAKSILAGLDLNCGSFLGNHTENAVKKGLIDEAAINKAISNNFATLMRLGFFDGNPKNQPYGGLGPKDVCTVENRELAVETARQGIVLLKNSAGSLPLSPSAIKTLAVIGPNANVTKTMIGNYEGVACKYTTPLQGLERTVLTTKYHRGCFNVTCTEADLDSAKTLAASADATVLVMGADQTIEKETLDRIDLNLPGKQQELVTQVAKAARGPVVLVIMSGGGFDITFAKNDEKITSIMWVGYPGEAGGIAIADVIFGRHNPSGKLPMTWYPQSYVEKVPMTNMNMRPDKSNGYLGRTYRFYIGETVYAFGDGLSYTNFSHQLIKAPKFVSLNLDESQSCRSPECQSLDAIGPHCEKAVGERSDFEVQLKVRNVGDREGTETVFLFTTPPEVHGSPRKQLLGFEKIRLGKKEETVVRFKVDVCKDLGVVDEIGKRKLALGHHLLHVGSLKHSFNISV
Protein: LRR receptor-like serine/threonine-protein kinase GHR1 (EC 2.7.11.1) (Protein GUARD CELL HYDROGEN PEROXIDE-RESISTANT 1) (AtGHR1) (Protein RADICAL-INDUCED CELL DEATH 7) (C0LGQ9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Receptor kinase acting as an early component in abscisic acid (ABA) signaling. Required for darkness, ABA, high CO(2) and hydrogen peroxide (H(2)O(2)) induction of S-type anion currents in guard cells leading to stomatal closure, possibly via the phosphorylation and activation of the anion channel SLAC1 and as a scaffolding component. Seems to act in parallel with SRK2E/OST1 in the ABA signaling pathway which regulates stomatal movement. Binds ATP. Involved in the local and/or systemic stomatal responses (e.g. stomatal closure) to light stress.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22730405, ECO:0000269|PubMed:30361234}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Guard cell S-type anion channel SLAC1
- Calcium-dependent protein kinase 3
- Protein phosphatase 2C 77
- Mitogen-activated protein kinase 12
- Serine/threonine-protein kinase SRK2E
- Protein DETOXIFICATION 56
- Calcium-dependent protein kinase 6
- Calcium-dependent protein kinase 23
- Mitogen-activated protein kinase 9
- Protein phosphatase 2C 56
Sequence:
MNLSRILLLSMFFLSAMGQLPSQDIMALLEFKKGIKHDPTGFVLNSWNDESIDFNGCPSSWNGIVCNGGNVAGVVLDNLGLTADADFSLFSNLTKLVKLSMSNNSLSGVLPNDLGSFKSLQFLDLSDNLFSSSLPKEIGRSVSLRNLSLSGNNFSGEIPESMGGLISLQSLDMSSNSLSGPLPKSLTRLNDLLYLNLSSNGFTGKMPRGFELISSLEVLDLHGNSIDGNLDGEFFLLTNASYVDISGNRLVTTSGKLLPGVSESIKHLNLSHNQLEGSLTSGFQLFQNLKVLDLSYNMLSGELPGFNYVYDLEVLKLSNNRFSGSLPNNLLKGDSLLLTTLDLSGNNLSGPVSSIMSTTLHTLDLSSNSLTGELPLLTGGCVLLDLSNNQFEGNLTRWSKWENIEYLDLSQNHFTGSFPDATPQLLRANHLNLSYNKLTGSLPERIPTHYPKLRVLDISSNSLEGPIPGALLSMPTLEEIHLQNNGMTGNIGPLPSSGSRIRLLDLSHNRFDGDLPGVFGSLTNLQVLNLAANNLSGSLPSSMNDIVSLSSLDVSQNHFTGPLPSNLSSNIMAFNVSYNDLSGTVPENLKNFPPPSFYPGNSKLVLPAGSPGSSASEASKNKSTNKLVKVVIIVSCAVALIILILVAILLFCICKSRRREERSITGKETNRRAQTIPSGSGGGMVVSAEDLVASRKGSSSEILSPDEKLAVATGFSPSKTSNLSWSPGSGDSFPADQQLARLDVRSPDRLVGELHFLDDSIKLTPEELSRAPAEVLGRSSHGTSYRATLDNGVFLTVKWLREGVAKQRKEFAKEVKKFSNIRHPNVVTLRGYYWGPTQHEKLILSDYISPGSLASFLYDRPGRKGPPLAWTQRLKIAVDVARGLNYLHFDRAVPHGNLKATNILLDGAELNARVADYCLHRLMTQAGTVEQILDAGILGYRAPELAASRKPLPSFKSDVYAFGVILLEILTGRCAGDVITGEQEGVDLTDWVRLRVAEGRGAECFDSVLTQEMGSDPVTEKGMKEVLGIALRCIRSVSERPGIKTIYEDLSSI
Protein: M-phase phosphoprotein 9 (A6H5Y1)
Organism: Mus musculus (Mouse)
Function: Negatively regulates cilia formation by recruiting the CP110-CEP97 complex (a negative regulator of ciliogenesis) at the distal end of the mother centriole in ciliary cells. At the beginning of cilia formation, MPHOSPH9 undergoes TTBK2-mediated phosphorylation and degradation via the ubiquitin-proteasome system and removes itself and the CP110-CEP97 complex from the distal end of the mother centriole, which subsequently promotes cilia formation (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q99550}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q99550}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q99550}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:30375385}. Note=Localizes to the distal and proximal end of centriole pairs in duplicated centrosomes. In ciliated cells, localizes to the distal and proximal end of daughter centriole and proximal of the mother centriole but not in the distal end of the mother centriole (By similarity). Recruited by KIF24 to the distal end of mother centriole where it forms a ring-like structure (By similarity). {ECO:0000250|UniProtKB:Q99550}.
Interaction partners:
- DNA repair protein RAD51 homolog 1
- Fanconi anemia group M protein homolog
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
Sequence:
MEDFDLVENLQKTSPSVESDIKSAPQSLGLSLHANRSSPHLSTNGVSSFSGKTGPPVIQGTVEVLTALRQDLQNSGRTDSELWKSCERIQEEIRKLVKLQLSHASRPSCSSSSVSEQVSAETQMGFFSENSERNESVVSSPASKEPETQPASSTSYPDCHVDSSSVSSGYGTFCILDMNTHKAKEPTEPLEPGAASQGQHPASVVQAHGPAGGAAAINFFTQTPEELCASLKEDGSTFPGEFDRNFLGENKISEVYSGKANSGKSVTSWAQRLKQNQSKQAHTEDDCSGPKPGSELNWKPPADTFDLAADAARPCAFYINKPAESPSSWLSDSGTGLTYWKLEEKDMYHSLPETLEKTFAPSPAERPLSQVLTLDPGAIRMKPKEHVAGIQAHGFLHALDDRISFSPDSVLEPSLSRHSDTDSSSQASHNPSQVSGFSKYPSTTRASPVDTWKNHAFQRESRTSSTIPSRYTITSNDISVKTVDEENTVTVASVSQSQLPGTANSVPECISLASLEDPVMLSKIRQNLKEKHARHVADLRAYYESEISSLKQKLEAKDISAVEEWKKKNEILADRCGQLDSALNEATSRVRTLEKNNNLLEIEVSDLRERFNAASSASKVLQERIEEMRTSNKEKDNTITRLKCRLQDLEEAFENAYKLSDDKEARLRQENKMFQDLLGEYESLGKEHGRVKDTLNTTENKLLDAHTQISDLKRTISKLEAQVKQAEHESMLSLRNGAKVPERPSRSNSVATSDVSRRKWLIPGAEYSIFTGQPLDPRDRKLDKQLEEALVPGYHSPPEKDSSLGSSPASLLVKKKRDTPDTPPIIKALKELDEERVFKSWGTQTEKEDSSSKLVNSRQTEPSVNTGRSPEKCAQQRPKRQTSASQRSSSLPPSSRKANTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPVRFDILLDDLDTVPVSTLQQTTAKKQLQFLLDDSEEKKYSEKNSDDPVNPSSCPEHSPNGLKKVSTRQAWEKSKSVSLEQCQPGSAAPQDNGFEYTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLEKINRELGSVRMTLKKFHVLRSSANL
Protein: Ribosome biogenesis protein BOP1 homolog (Pescadillo-interacting protein 1) (AtPEIP1) (Protein BLOCK OF CELL PROLIFERATION 1) (F4IH25)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (By similarity). Plays an essential role in cell growth and survival through its regulation of ribosome biogenesis and mitotic progression.
Subcellular location: Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03027, ECO:0000269|PubMed:23909681, ECO:0000269|PubMed:25443833}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03027}.
Interaction partners:
- Pescadillo homolog
- Nucleolar complex-associated protein 3
- Ribosome assembly factor mrt4
- Ribosome biogenesis protein WDR12 homolog
- Transducin/WD40 repeat-like superfamily protein
- AT5g20600/F7C8_190
- Probable rRNA-processing protein EBP2 homolog
- Guanine nucleotide-binding protein-like NSN1
- 60S ribosome subunit biogenesis protein NIP7 homolog
- DAR GTPase 3, chloroplastic
Sequence:
MTKRSKGANEDKLIETKSKNVSGKSQKQKKPVEAESLKEEDLLQASGTDSDYDGDSLPGSLNSDDFDSDFSDSEDDGTHEGTEDGDVEFSDDDDVLEHDGSIDNEDDDGSEHVGSDNNEEHGSDEDSERGEAVEESDSSEDEVPSRNTVGNVPLKWYEDEKHIGYDLTGKKITKKEKQDKLDSFLATIDDSKTWRKIYDEYNDEDVELTKEESKIVQRILKGEAPHADFDPYAPYVEWFKHDDAIHPLSSAPEPKRRFIPSKWEAKKVVKIVRAIRKGWIKFDKPEEEPNVYLLWGDDSTSDQKSKHLTYIPPPKLKLPGHDESYNPSLEYIPTEEEKASYELMFEEDRPKFIPTRFTSLRSIPAYENALKESFERCLDLYLCPRVRKKRINIDPESLKPKLPSRKDLRPYPNSCYLEYKGHTGAVTSISTDSSGEWIASGSTDGSVRMWEVETGRCLKVWQFDEAIMCVAWNPLSRLPVLAVAMGRDLFFLNTELGTDEEQEITKERLHSGNIPEPDASVAAIVTWLPDELYGGIKIRHFKSISSIDWHRKGDYLSTVMASGETRGVVLHQLSKQKTQRLPFKIRGLPVCTLFHPSLSYFFVATRKDVRVYNLLKPGEATKKLETGLREISSMAIHPGGDNLIVGSKEGKMCWFDMDLSSKPYKTLKNHPKDITNVAVHRSYPLFASCSEDSTAYVFHGMVYNDLNQNPLIVPLEILRGHSSKGGVLDCKFHPRQPWLFTAGADSIIKLYCH
Protein: Large ribosomal subunit protein bL12m (54S ribosomal protein L12, mitochondrial) (Mitochondrial-nucleoid protein 1) (Q9USJ9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein bL36m
- Large ribosomal subunit protein bL9m
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein bL19m
- Small ribosomal subunit protein bS6m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein bL28m
- Large ribosomal subunit protein bL33m
- Small ribosomal subunit protein uS9m
Sequence:
MFRIASRQTRNLRALSSSKNWARSLVNTRSFRAAASVQNNNAQIGEMVDKISSLSLLETSELVKQLKEKLNIAEIAPMAAVAPAVASAAPSEEKAPEEKKEEKTTWNLKLESFDAGSKAKVIKEVKSLLGLSLVDAKKFVESAPKVLKENILKEDAEAIKSKLEKLSCKVVLE
Protein: Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Solute carrier family 45 member 2) (Q9UMX9)
Organism: Homo sapiens (Human)
Function: Proton-associated glucose and sucrose transporter (By similarity). May be able to transport also fructose (By similarity). Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis. Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR.
Subcellular location: Melanosome membrane {ECO:0000269|PubMed:17081065, ECO:0000269|PubMed:32966160}; Multi-pass membrane protein {ECO:0000269|PubMed:17081065}. Note=Enriched in mature melanocyte membrane subdomains. {ECO:0000269|PubMed:32966160}.
Interaction partners:
- Sodium/potassium/calcium exchanger 5
- P protein
- Tyrosinase
- 5,6-dihydroxyindole-2-carboxylic acid oxidase
- Melanocyte-stimulating hormone receptor
- Sodium/potassium/calcium exchanger 4
- Tumor necrosis factor receptor superfamily member EDAR
- Melanoma antigen recognized by T-cells 1
- Two pore channel protein 2
- L-dopachrome tautomerase
Sequence:
MGSNSGQAGRHIYKSLADDGPFDSVEPPKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPVVGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMIGVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYLLGAIDWAHLELGRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPLTEVAKGIPPQQTPQDPPLSSDGMYEYGSIEKVKNGYVNPELAMQGAKNKNHAEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYERGVEVGCWGLCINSVFSSLYSYFQKVLVSYIGLKGLYFTGYLLFGLGTGFIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEEKERQQAPGGDPDNSVRGKGMDCATLTCMVQLAQILVGGGLGFLVNTAGTVVVVVITASAVALIGCCFVALFVRYVD
Protein: Chondrolectin (Q568T5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in the development of the nervous system such as in neurite outgrowth and elongation. Involved in motor axon growth and guidance. Required for correct interactions of motor axons with the horizontal myoseptum.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Transmembrane protein 41B
- Neurexin 2.
- Lysosome-associated membrane glycoprotein 5
- GC-rich promoter-binding protein 1-like 1
Sequence:
MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV
Protein: Cellulose synthase A catalytic subunit 1 [UDP-forming] (AtCesA1) (EC 2.4.1.12) (Protein RADIALLY SWOLLEN 1) (AtRSW1) (O48946)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation. Required during embryogenesis for cell elongation, orientation of cell expansion and complex cell wall formations, such as interdigitated pattern of epidermal pavement cells, stomatal guard cells and trichomes. Plays a role in lateral roots formation, but seems not necessary for the development of tip-growing cells such as root hairs. The presence of each protein CESA1 and CESA6 is critical for cell expansion after germination.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cellulose synthase A catalytic subunit 3
- Cellulose synthase A catalytic subunit 6
- Endoglucanase 25
- Protein CELLULOSE SYNTHASE INTERACTIVE 1
- Cellulose synthase A catalytic subunit 2
- Cellulose synthase A catalytic subunit 5
- Chitinase-like protein 1
- Glucomannan 4-beta-mannosyltransferase 7
- Probable glucan 1,3-alpha-glucosidase
- Xyloglucan glycosyltransferase 4
Sequence:
MEASAGLVAGSYRRNELVRIRHESDGGTKPLKNMNGQICQICGDDVGLAETGDVFVACNECAFPVCRPCYEYERKDGTQCCPQCKTRFRRHRGSPRVEGDEDEDDVDDIENEFNYAQGANKARHQRHGEEFSSSSRHESQPIPLLTHGHTVSGEIRTPDTQSVRTTSGPLGPSDRNAISSPYIDPRQPVPVRIVDPSKDLNSYGLGNVDWKERVEGWKLKQEKNMLQMTGKYHEGKGGEIEGTGSNGEELQMADDTRLPMSRVVPIPSSRLTPYRVVIILRLIILCFFLQYRTTHPVKNAYPLWLTSVICEIWFAFSWLLDQFPKWYPINRETYLDRLAIRYDRDGEPSQLVPVDVFVSTVDPLKEPPLVTANTVLSILSVDYPVDKVACYVSDDGSAMLTFESLSETAEFAKKWVPFCKKFNIEPRAPEFYFAQKIDYLKDKIQPSFVKERRAMKREYEEFKVRINALVAKAQKIPEEGWTMQDGTPWPGNNTRDHPGMIQVFLGHSGGLDTDGNELPRLIYVSREKRPGFQHHKKAGAMNALIRVSAVLTNGAYLLNVDCDHYFNNSKAIKEAMCFMMDPAIGKKCCYVQFPQRFDGIDLHDRYANRNIVFFDINMKGLDGIQGPVYVGTGCCFNRQALYGYDPVLTEEDLEPNIIVKSCCGSRKKGKSSKKYNYEKRRGINRSDSNAPLFNMEDIDEGFEGYDDERSILMSQRSVEKRFGQSPVFIAATFMEQGGIPPTTNPATLLKEAIHVISCGYEDKTEWGKEIGWIYGSVTEDILTGFKMHARGWISIYCNPPRPAFKGSAPINLSDRLNQVLRWALGSIEILLSRHCPIWYGYHGRLRLLERIAYINTIVYPITSIPLIAYCILPAFCLITDRFIIPEISNYASIWFILLFISIAVTGILELRWSGVSIEDWWRNEQFWVIGGTSAHLFAVFQGLLKVLAGIDTNFTVTSKATDEDGDFAELYIFKWTALLIPPTTVLLVNLIGIVAGVSYAVNSGYQSWGPLFGKLFFALWVIAHLYPFLKGLLGRQNRTPTIVIVWSVLLASIFSLLWVRINPFVDANPNANNFNGKGGVF
Protein: Non-structural protein ORF4b (ORF4b) (A3EX97)
Organism: Bat coronavirus HKU4 (BtCoV) (BtCoV/HKU4/2004)
Function: Plays a role in the inhibition of host innate immunity by inhibiting the interaction between host IKBKE and MAVS. In turn, this inhibition prevents the production of host interferon beta. Additionally, may also interfere with host antiviral response within the nucleus.
Subcellular location: Host nucleus {ECO:0000269|PubMed:24443473}. Host nucleus, host nucleolus {ECO:0000250|UniProtKB:K9N643}. Host cytoplasm {ECO:0000250|UniProtKB:K9N643}. Note=Mainly localized in the host nucleus. {ECO:0000250|UniProtKB:K9N643}.
Interaction partners:
Sequence:
MSIVLRLLSVLKHQQNKMQLDLSVNSYKLLDYSMEWSSDSVVLPPTSSDKTVMMPAKATSSRKRHRKPKLQYAKRRFSPVNPNDLVLVQQEPTHCVRLVFPLSKRWIHFDGLVYSLARLNVSMTVDYHVTLALIYAPEAGECFGNFLHLCPLLKDCLLEFKKLCVLGKTLTILASEWPFFTDVKKNKDNLTVPKAVEWLKEHGYEIYNSQLPLHMSLAKLHDLPQAQFAEAAGLCHYFDPREFALPCALEVVKIGGGKVNGRSIPLARFPINNEFKFIPYLYQCV
Protein: Nucleolar protein 56 (A0A1D8PU46)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 10
- SnoRNA-binding rRNA-processing protein
- rRNA 2'-O-methyltransferase fibrillarin
- H/ACA ribonucleoprotein complex subunit CBF5
- GTPase
- Utp4p
- 13 kDa ribonucleoprotein-associated protein
- rRNA-processing protein
- SnoRNA-binding rRNA-processing protein
- Nucleolar protein 58
Sequence:
MPGLDYLLFEEATGYGIFKVLIQQDDIASRSKEVQEAANDLSKFSKMVELVSFAPFKGAAQALENANDISEGLVSPYLQSILELNLPKTSSKKRIALGVSDKNLGPSIKEVFPNVDVLSNEIVQDFLRGIRVHGAKLFKDLQEGDIERAQLGLGHAFSRAKVKFSVQKNDNHIIQAIALLDQLDKDINTFAMRVKEWYGWHFPELAKIVPDNYSYAKLALSIKDKASLTDDSLHDVAAILNDDSGLAQRVIDNAKISMGQDISEQDMDNVITFAQRVVNLYEYRQQLYKYLTDKMHTVAPNLSTLIGEVVGARLISHAGSLTNLSKQAASTVQILGAEKALFRALKTKGNTPKYGLIYHSSFIGKASAKNKGRISRYLANKCSIASRIDNYSEEPTTAFGEILKKQVEDRLKFYDTGSAPMKNSDAIKAALALNGQDLAGAEEQKDVDMVSDEEQVKKEKKEKKEKKEKKDKKEKKEKKDKKEKKDKKEKKDKKDKKRKSDDGEETPKKKKKKSKD
Protein: LD25351p (PAPS synthetase, isoform A) (PAPS synthetase, isoform B (EC 2.7.1.25, EC 2.7.7.4)) (PAPS synthetase, isoform C) (PAPS synthetase, isoform G) (Q961A8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSEVPESSKKRQKTCLQVATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGLDGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGLKFYEIFVDTPLDVCETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHGYTVRESTQKLVTLLEQEGIIPRSLRDVDLLPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQSGMDGSYRENHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVAILRRPEFYFQRKEERLARQFGTSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLRNPIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTVLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKMAQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRILATYYQNLPQS
Protein: Biotinidase (Biotinase) (EC 3.5.1.12) (P43251)
Organism: Homo sapiens (Human)
Function: Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
Subcellular location: Secreted, extracellular space {ECO:0000305|PubMed:9099842, ECO:0000305|PubMed:9654207}.
Interaction partners:
- Biotin--protein ligase
- Pyruvate carboxylase, mitochondrial
- Alpha-aminoadipic semialdehyde synthase, mitochondrial
- Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
- Harmonin-binding protein USHBP1
- Propionyl-CoA carboxylase alpha chain, mitochondrial
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
- Thiamine transporter 2
Sequence:
MAHAHIQGGRRAKSRFVVCIMSGARSKLALFLCGCYVVALGAHTGEESVADHHEAEYYVAAVYEHPSILSLNPLALISRQEALELMNQNLDIYEQQVMTAAQKDVQIIVFPEDGIHGFNFTRTSIYPFLDFMPSPQVVRWNPCLEPHRFNDTEVLQRLSCMAIRGDMFLVANLGTKEPCHSSDPRCPKDGRYQFNTNVVFSNNGTLVDRYRKHNLYFEAAFDVPLKVDLITFDTPFAGRFGIFTCFDILFFDPAIRVLRDYKVKHVVYPTAWMNQLPLLAAIEIQKAFAVAFGINVLAANVHHPVLGMTGSGIHTPLESFWYHDMENPKSHLIIAQVAKNPVGLIGAENATGETDPSHSKFLKILSGDPYCEKDAQEVHCDEATKWNVNAPPTFHSEMMYDNFTLVPVWGKEGYLHVCSNGLCCYLLYERPTLSKELYALGVFDGLHTVHGTYYIQVCALVRCGGLGFDTCGQEITEATGIFEFHLWGNFSTSYIFPLFLTSGMTLEVPDQLGWENDHYFLRKSRLSSGLVTAALYGRLYERD