wanglab/gogpt-training-data huggingface dataset:
Protein: Terephthalate 1,2-dioxygenase, terminal oxygenase component subunit alpha 1 (TPADO terminal oxygenase component) (EC 1.14.12.15) (TER dioxygenase system) (TERDOS) (Terephthalate 1,2-dioxygenase large subunit 1) (Q3C1E3)
Organism: Comamonas sp
Function: Component of the terephthalate 1,2-dioxygenase multicomponent enzyme system which catalyzes the dioxygenation of terephthalate (TER/TPA) to 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylic acid (DCD). It can also use 2,5-dicarboxypyridine (PDC) and 1,4-napthalenedicarboxylic acid (NDC) as substrates, and preferentially uses NADPH which is the physiological electron donor.
Interaction partners:
Sequence:
MQESIIQWHGATNTRVPFGIYTDTANADQEQQRIYRGEVWNYLCLESEIPGAGDFRTTFAGETPIVVVRDADQEIYAFENRCAHRGALIALEKSGRTDSFQCVYHAWSYNRQGDLTGVAFEKGVKGQGGMPASFCKEEHGPRKLRVAVFCGLVFGSFSEDVPSIEDYLGPEICERIERVLHKPVEVIGRFTQKLPNNWKLYFENVKDSYHASLLHMFFTTFELNRLSQKGGVIVDESGGHHVSYSMIDRSAKDDSYKDQAIRSDNERYRLKDPSLLEGFEEFEDGVTLQILSVFPGFVLQQIQNSIAVRQLLPKSISSSELNWTYLGYADDSTEQRKVRLKQANLIGPAGFISMEDGAVGGFVQRGIAGAANLDAVIEMGGDHEGSSEGRATETSVRGFWKAYRKHMGQEMQA
Protein: Large ribosomal subunit protein eL8z (60S ribosomal protein L7a-1) (P49692)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL4y
- Large ribosomal subunit protein uL22y
- Small ribosomal subunit protein eS24z
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein eL13z
- Large ribosomal subunit protein uL4z
- Small ribosomal subunit protein eS1y
- Small ribosomal subunit protein eS6y
- Small ribosomal subunit protein uS12y
- Large ribosomal subunit protein uL18y
Sequence:
MAPKKGVKVAAKKKTAEKVSNPLFERRPKQFGIGGALPPKKDLSRYIKWPKSIRLQRQKRILKQRLKVPPALNQFTKTLDKNLATSLFKVLLKYRPEDKAAKKERLVKKAQAEAEGKPSESKKPIVVKYGLNHVTYLIEQNKAQLVVIAHDVDPIELVVWLPALCRKMEVPYCIVKGKSRLGAVVHQKTASCLCLTTVKNEDKLEFSKILEAIKANFNDKYEEYRKKWGGGIMGSKSQAKTKAKERVIAKEAAQRMN
Protein: Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21) (O14578)
Organism: Homo sapiens (Human)
Function: Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Kinesin-like protein KIF14
- Kinesin-like protein KIF20A
- Kinesin-like protein KIF23
- Anillin
- Abnormal spindle-like microcephaly-associated protein
- Transforming protein RhoA
- Cyclin-dependent kinase inhibitor 1B
- Chromosome-associated kinesin KIF4A
- Rho-related GTP-binding protein RhoB
- Rho-related GTP-binding protein RhoC
Sequence:
MLKFKYGARNPLDAGAAEPIASRASRLNLFFQGKPPFMTQQQMSPLSREGILDALFVLFEECSQPALMKIKHVSNFVRKYSDTIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDFGSAAKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKERLKFEGLCCHPFFSKIDWNNIRNSPPPFVPTLKSDDDTSNFDEPEKNSWVSSSPCQLSPSGFSGEELPFVGFSYSKALGILGRSESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKESSTPEEFSRRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAEYATHFTEAFCRDKMNSPGLQTKEPSSSLHLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADVPYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGNSLLKLEGDDRLDMNCTLPFSDQVVLVGTEEGLYALNVLKNSLTHVPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDISPNIFEAVKGCHLFGAGKIENGLCICAAMPSKVVILRYNENLSKYCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTLEEFLDKNDHSLAPAVFAASSNSFPVSIVQVNSAGQREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSAGTPARAYLDIPNPRYLGPAISSGAIYLASSYQDKLRVICCKGNLVKESGTEHHRGPSTSRSSPNKRGPPTYNEHITKRVASSPAPPEGPSHPREPSTPHRYREGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSSRGRLPAGAVRTPLSQVNKVWDQSSV
Protein: Pleiomorphic adenoma gene-like 1 (Zinc finger protein ZAC1) (Q9JLQ4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Mesoderm-specific transcript protein
- Retrotransposon-derived protein PEG10
- Phosphatase and actin regulator
- Growth factor receptor-bound protein 10
- Small nuclear ribonucleoprotein-associated protein N
- Neuronatin
Sequence:
MAPFRCQKCGKSFVTLEKFTIHNYSHSRERPFKCSKAECGKAFVSKYKLMRHMATHSPQKIHQCTHCEKTFNRKDHLKNHLQTHDPNKISYACDDCGKKYHTMLGYKRHLALHSASNGDLTCGVCTLELGSTEVLLDHLKSHAEEKANQAPREKKYQCDHCDRCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRHTKKTHSQELMQENMQAGDYQSNFQLIAPSTSFQIKVDPMPPFQLGAAPENGLDGGLPPEVHGLVLAAPEEAPQPMPPLEPLEPLEPLEPLEPMQSLEPLQPLEPMQPLEPMQPLEPMQPLEPLEPLEPMQPLEPMQPLEPMQPMLPMQPMQPMQPMQPMLPMQPMLPMQPMQPMQPMLPMPEPSFTLHPGVVPTSPPPIILQEHKYNPVPTSYAPFVGMPVKADGKAFCNVGFFEEFPLQEPQAPLKFNPCFEMPMEGFGKVTLSKELLVDAVNIAIPASLEISSLLGFWQLPPPTPQNGFVNSTIPVGPGEPLPHRITCLAQQQPPPLPPPPPLPLPQPLPVPQPLPQPQMQPQFQLQIQPQMQPQMQLQPLQLQLPQLLPQLQPQQQPDPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEEEQEEAEEEAEEGAEEGAEPEAQAEEEEEEEEAEEPQPEEAQIAVSAVNLGQPPLPPTPHIFTAGSNTAILPHFHHAFR
Protein: Octanoyltransferase LipM (EC 2.3.1.181) (Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase) (P54511)
Organism: Bacillus subtilis (strain 168)
Function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. Is also able to catalyze the reverse reaction. Octanoyl-CoA can also act as a substrate although very poorly. Does not display lipoate protein ligase activity, despite its sequence similarity to LplA.
Interaction partners:
- Lipoyl synthase
- Octanoyl-[GcvH]:protein N-octanoyltransferase
- Glycine cleavage system H protein
- Protein LplB
- Enoyl-[acyl-carrier-protein] reductase FabI
- Dihydrolipoyl dehydrogenase
- Dihydrolipoyl dehydrogenase
- 3-oxoacyl-[acyl-carrier-protein] synthase 2
- Enoyl-[acyl-carrier-protein] reductase FabL
- Dihydrolipoyl dehydrogenase
Sequence:
MQKETWRFIDSGNASPAFNMALDEALLYWHSEKKIPPVIRFYGWNPATLSVGYFQNIKKEINFEAVHKYNLGFVRRPTGGRGVLHDQELTYSVIVSEEHPEMPATVTEAYRVISEGILQGFRNLGLDAYFAIPRTEKEKESLKNPRSSVCFDAPSWYELVVEGRKVAGSAQTRQKGVILQHGSILLDLDEDKLFDLFLYPSERVRERMQRNFKNKAVAINELIEKRVTMDEARKAFKEGFETGLNIHLEPYELSQEELDFVHHLAETKYASDEWNYKR
Protein: Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate hydrolase) (AtFAH) (Protein SHORT-DAY SENSITIVE CELL DEATH 1) (Q8RW90)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Converts fumarylacetoacetate to acetoacetate and fumarate. Involved in tyrosine catabolic pathway. Catalyzes the final step in the tyrosine degradation pathway.
Interaction partners:
- Glutathione S-transferase Z2
- Oxaloacetate tautomerase FAHD1, mitochondrial
- Glutathione S-transferase Z1
- Oxaloacetate tautomerase FAHD2, mitochondrial
- Homogentisate 1,2-dioxygenase
- 4-hydroxyphenylpyruvate dioxygenase
- Dihydroceramide fatty acyl 2-hydroxylase FAH1
- Fumarate hydratase 1, mitochondrial
- Fumarate hydratase 2
- Succinate dehydrogenase flavoprotein subunit 1, mitochondrial
Sequence:
MALLKSFIDVGSDSHFPIQNLPYGVFKPESNSTPRPAVAIGDLVLDLSAISEAGLFDGLILKDADCFLQPNLNKFLAMGRPAWKEARSTLQRILSSNEPILRDNDVLRRKSFHQMSKVEMIVPMVIGDYTDFFASMHHAKNCGLMFRGPENAINPNWFRLPIAYHGRASSIVISGTDIIRPRGQGHPQGNSEPYFGPSKKLDFELEMAAVVGPGNELGKPIDVNNAADHIFGLLLMNDWSARDIQAWEYVPLGPFLGKSFGTTISPWIVTLDALEPFGCQAPKQDPPPLPYLAEKESVNYDISLEVQLKPSGRDDSCVITKSNFQNLYWTITQQLAHHTVNGCNLRPGDLLGTGTISGPEPDSYGCLLELTWNGQKPLSLNGTTQTFLEDGDQVTFSGVCKGDGYNVGFGTCTGKIVPSPP
Protein: Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120) (Q9H0E9)
Organism: Homo sapiens (Human)
Function: May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.
Subcellular location: Nucleus {ECO:0000269|PubMed:25593309}.
Interaction partners:
- E1A-binding protein p400
- DNA methyltransferase 1-associated protein 1
- Chromatin modification-related protein MEAF6
- YEATS domain-containing protein 4
- Transformation/transcription domain-associated protein
- Histone acetyltransferase KAT5
- Mortality factor 4-like protein 1
- Inhibitor of growth protein 3
- RuvB-like 2
- RuvB-like 1
Sequence:
MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFMGHEWVWLDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGNWRETEDPEAEELEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPLCISSNESSEGCCPPSGTRQEGREIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPEVASAPSVICTVQGLLTESEEGEAQQESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPLVDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRQEVLEQIQVLNIWLDKRKGSSSLEGEPANPVDDGKPVF
Protein: Receptor-like kinase LIP1 (EC 2.7.11.-) (Protein LOST IN POLLEN TUBE GUIDANCE 1) (AtLIP1) (Q1PDW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in pollen tube guidance into micropyle. Participates in perception of the ovule-secreted peptide signal LURE1.
Subcellular location: Cell membrane {ECO:0000269|PubMed:23684977}; Lipid-anchor {ECO:0000305|PubMed:23684977}. Cytoplasm {ECO:0000269|PubMed:23684977}. Note=In pollen tubes, mainly located in the plasma membrane to the tip region. {ECO:0000269|PubMed:23684977}.
Interaction partners:
- Octanoyltransferase LIP2p2, chloroplastic
- Octanoyltransferase LIP2p, chloroplastic
- Triacylglycerol lipase SDP1
- Triacylglycerol lipase 2
- Octanoyltransferase LIP2, mitochondrial
- Triacylglycerol lipase 1
- Lipoyl synthase, chloroplastic
- Lipoyl synthase, mitochondrial
- Putative clathrin assembly protein At1g03050
- Protein SEEDLING PLASTID DEVELOPMENT 1
Sequence:
MIIMMNCFPCFTSQKSRNAPCTTNETNDDNVEHDEFRPPVVATTKRTEEREPAEQQPPVKTFNFRELATATKNFRQECLLGEGGFGRVYKGTLQSTGQLVAVKQLDKHGLHGNKEFLAEVLSLAKLEHPNLVKLIGYCADGDQRLLVFEYVSGGSLQDHLYEQKPGQKPMDWITRMKIAFGAAQGLDYLHDKVTPAVIYRDLKASNILLDAEFYPKLCDFGLHNLEPGTGDSLFLSSRVMDTYGYSAPEYTRGDDLTVKSDVYSFGVVLLELITGRRAIDTTKPNDEQNLVAWAQPIFKDPKRYPDMADPLLRKNFSERGLNQAVAITSMCLQEEPTARPLISDVMVALSFLSMSTEDGIPATVPMESFRDKSMSIALSRHGSCSVTPFCISRKDVGNKSSSSSDSEDEEEEKEQKAEKEEESTSKKRQEQEETATDSDDESDSNSEKDQEEEQSQLEKARESSSSSSDSGSERRSIDETNATAQSLKISYSNYSSEEEDNEKLSSKSSCKSNEESTFSRYDSGRDHDDSSRNTSMRINSLAHDDKEEDEEENHETRSYSDHDDSPRNTSMRINSLSHDDDEEEEEENHQTRLEHIHSSKSEDQSVYSDDDAGESGESSLHRIEAKEEEHISSDHD
Protein: Interferon alpha-1 (IFN-alpha-1) (P01572)
Organism: Mus musculus (Mouse)
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Subcellular location: Secreted.
Interaction partners:
- Interferon alpha/beta receptor 1
- Interferon alpha-5
- Interferon alpha-6
- Signal transducer and activator of transcription 1
- Interferon regulatory factor 3
- Interferon regulatory factor 7
- Interferon gamma receptor 1
- Tyrosine-protein kinase JAK2
- Epidermal growth factor receptor
- Interferon beta
Sequence:
MARLCAFLMVLAVLSYWPTCSLGCDLPQTHNLRNKRALTLLVQMRRLSPLSCLKDRKDFGFPQEKVDAQQIKKAQAIPVLSELTQQILNIFTSKDSSAAWNTTLLDSFCNDLHQQLNDLQGCLMQQVGVQEFPLTQEDALLAVRKYFHRITVYLREKKHSPCAWEVVRAEVWRALSSSANVLGRLREEK
Protein: Palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378) (Q9ULC8)
Organism: Homo sapiens (Human)
Function: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (Probable). Through the palmitoylation of ABCA1 regulates the localization of the transporter to the plasma membrane and thereby regulates its function in cholesterol and phospholipid efflux (Probable). Could also pamitoylate the D(2) dopamine receptor DRD2 and regulate its stability and localization to the plasma membrane (Probable). Could also play a role in glutamatergic transmission (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:16647879, ECO:0000269|PubMed:26535572, ECO:0000269|PubMed:34599882}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q5Y5T5}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Proline dehydrogenase 1, mitochondrial
- Proline dehydrogenase
- Catechol O-methyltransferase
- Paralemmin-1
- Phospholipid-transporting ATPase ABCA1
- Integral membrane protein DGCR2/IDD
- Reticulon-4 receptor
- Mitochondrial ribosomal protein L40
- Golgin subfamily A member 7
Sequence:
MPRSPGTRLKPAKYIPVATAAALLVGSSTLFFVFTCPWLTRAVSPAVPVYNGIIFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKNVDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSAHMVGVVAFGLVYVLNHAEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCCGNVEHVLCSPLAPRYVVEPPRLPLAVSLKPPFLRPELLDRAAPLKVKLSDNGLKAGLGRSKSKGSLDRLDEKPLDLGPPLPPKIEAGTFSSDLQTPRPGSAESALSVQRTSPPTPAMYKFRPAFPTGPKVPFCGPGEQVPGPDSLTLGDDSIRSLDFVSEPSLDLPDYGPGGLHAAYPPSPPLSASDAFSGALRSLSLKASSRRGGDHVALQPLRSEGGPPTPHRSIFAPHALPNRNGSLSYDSLLNPGSPGGHACPAHPAVGVAGYHSPYLHPGATGDPPRPLPRSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQADSLFGDSGVYDAPSSYSLQQASVLSEGPRGPALRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSVSRAPRTSSSSLQADQASSNAPGPRPSSGSHRSPARQGLPSPPGTPHSPSYAGPKAVAFIHTDLPEPPPSLTVQRDHPQLKTPPSKLNGQSPGLARLGPATGPPGPSASPTRHTLVKKVSGVGGTTYEISV
Protein: Peptidyl-prolyl cis-trans isomerase CYP18-3 (PPIase CYP18-3) (EC 5.2.1.8) (Cyclophilin of 18 kDa 3) (Cyclosporin A-binding protein) (Rotamase cyclophilin-1) (P34790)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in de-etiolation. Reduces the sensitivity to brassinosteroids by decreasing somehow the abundance of the partially dephosphorylated form of BES1. Triggers the activation of bacterial AvrRpt2 protease activity upon infection by P.syringae. Activated AvrRpt2 confers virulence in plant lacking the RPS2 resistance gene. In plants expressing RPS2, the AvrRpt2-mediated degradation of RIN4 activates RPS2, which induces hypersensitive response (HR) and plant resistance.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- UPF0235 protein At5g63440
- AT4g38690/F20M13_250
- Probable magnesium transporter NIPA6
- AT5g22320/MWD9_11
- Probable cysteine protease RD21C
- Cysteine proteinase RD21A
- At4g34930
- At1g09850
- Probable cysteine protease RD21B
- RPM1-interacting protein 4
Sequence:
MAFPKVYFDMTIDGQPAGRIVMELYTDKTPRTAENFRALCTGEKGVGGTGKPLHFKGSKFHRVIPNFMCQGGDFTAGNGTGGESIYGSKFEDENFERKHTGPGILSMANAGANTNGSQFFICTVKTDWLDGKHVVFGQVVEGLDVVKAIEKVGSSSGKPTKPVVVADCGQLS
Protein: PIN domain-containing protein (Q4GZ40)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGIYSDTDDDSPIGIEVVGEASSDSEEPNPHSTTKRKVSGAVDHNNGYNQKKNKRRRLKNKWEENPQLHETPDEEQISNVKKRVYVLDTCSIVEHIEWSILEEVAKYYLIIIPKKVMDELGKMEGGRGSTCNRVLNKLENEHTSNKMNVGFRLQRKNDKDKNVLSAARVNDDHILSCACSFRNEHDVVLVTSDNILKLKAYAEGIPTVSTLKDVTRLTNGLRGGKFE
Protein: Dro4 protein (Drosomycin 4) (Drosomycin-like 4) (Drosomycin-like F) (Q8IRD6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Dorsal-related immunity factor Dif
- Embryonic polarity protein dorsal
Sequence:
MAQIKGLFALLAVVTIVLMVANSASAVDCPSGRFSGPCWAWDGEQCRRLCREEGRVSGHCSASLKCWCEQC
Protein: Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1) (SCAMP 37) (P56603)
Organism: Rattus norvegicus (Rat)
Function: Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Recycling endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Intersectin-1
Sequence:
MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGGVKMPNVPNTQPAIMKPTEEHPAYTQITKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSSRAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNKNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNQM
Protein: Striatin (P70483)
Organism: Rattus norvegicus (Rat)
Function: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23015759}. Membrane {ECO:0000269|PubMed:23015759}; Peripheral membrane protein {ECO:0000269|PubMed:23015759}. Cell projection, dendritic spine {ECO:0000269|PubMed:23015759}. Note=CTTNBP2-binding may regulate dendritic spine distribution. {ECO:0000269|PubMed:23015759}.
Interaction partners:
- Striatin-interacting protein 1
- MOB-like protein phocein
- Serine/threonine-protein kinase 25
- Serine/threonine-protein kinase 24
- Striatin-4
- Striatin-3
- Programmed cell death protein 10
- CTTNBP2 N-terminal like
- Suppressor of IKBKE 1
- Cortactin-binding protein 2
Sequence:
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQFMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSDVTDREDDKNQDSVINGTEAEVKETAMIGKSELTDSASVLDNFKFLENAAADFSDEDEDEDIDGREKSVIDTSTIVRKKPLPDTSEDRDTKEALKEFDFLVASEEGDNESRSAGDGTDWEKEDQCLTPERWNVDQGVITRLKEQYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEQDISRADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLAYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQSWSTTNPNVDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWTTTEVAPALTVFNDNQELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDSTASSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV
Protein: Antitoxin VapB26 (O53778)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC26.
Interaction partners:
- Ribonuclease VapC26
- Twitching motility protein PilT
Sequence:
MDKTTVYLPDELKAAVKRAARQRGVSEAQVIRESIRAAVGGAKPPPRGGLYAGSEPIARRVDELLAGFGER
Protein: Peptidoglycan hydrolase (EC 3.2.1.17) (Q8KKF9)
Organism: Lactococcus lactis
Interaction partners:
Sequence:
MVNTQVKRVKKQKFIAGTALLLGMATFGMVGKADDLSSSNTNGGVDNSKVDNDNQESVKTSTEGVSSTTENANTVPESKVTSTVDSESAPSKTISAGTQSNISGTSDGSDSLPKTETSDSSSKPSTSNSSSKPSTSNSSSKPSTSNSSSNNNSATKPSTTTQAPPVAPSTTAPSATPSTTAPSNYYQNSSYNQTSTAAQIPNSSSDSAASVYSGPVLKKIEAAKPIEKIDSSSTEAFIKSIADRVRILAGKNNLYASIILAQAILESGSGQSNMTQQYFNIFNITGAYLGKSISFKTEEFSGNNPYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFATDPEYAQKLIEIIEEYNLNFYDNVDSTTQVLDSNIPESPLVASKLDSSTYPDYNGVEYPGADSYAFGNCTQYVYNRIIQLGGQIGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSFPPGVAGSSPEYGHVAFVEKVYPDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK
Protein: LOB domain-containing protein 20 (ASYMMETRIC LEAVES 2-like protein 21) (AS2-like protein 21) (Q9SRV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Thionin-2.1
- Mediator of RNA polymerase II transcription subunit 25
Sequence:
MADQQRGHNTSDSRRKSLAGKRTSQQTPTSSLSSGGVSMAAATTGTGTASPCGACKFLRRKCVSGCIFAPHFGSDQGAARFAAVHKVFGASNVSKLLHHIPVNRRHDAVVTISYEAQARLSDPVYGCVSTILALQQQVASLQAELSVVQSQLINSRVAMANVMQQQTHHQQQQQQLVVMQQPEYSNNSSASTTLAGAAMNSFTMTADAAAVSYDVMAPTNLEHSLQPMPPHQQRRGDYQHEDEEESGADFSVAVGSTAVASKVIFPAEDFHRR
Protein: RNA polymerase sigma-54 factor (Q0PAK4)
Organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Interaction partners:
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit beta'
- Sigma-54 associated transcriptional activator
- DNA-directed RNA polymerase subunit omega
- RNA polymerase sigma factor SigA
- RQC P-site tRNA stabilizing factor
- ABC-transporter ATP-binding protein
- Flagellar protein
- tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
Sequence:
MLKQKITQAPKTKISQTLRSWLPILQANIEDLKENLDKFAEDNPFLNVQDSIQTHDKGKNYFDSFYKHNVNSAFVDSKGLAKKSVYELLNEQILPPLFPTSKSQELAKKIIECLNEEGYFEHDEEFLKEYSLEEIERVRARFKFLDPVGVGAKDYKEAFLFALENMELDEDIDEFCRMLIMDFENIQNYTKEPLYKEALAVLKRFSTPPFLEYFEDSRIIVPDIFVYKENGEIKVKINDDYYPEISIQTDGLEHDFLSHYIKEAKNLVDALAMRKATLYKIGLMIVEYQYDFFMGKEIKPMTFKDLALDLERNASTISRAVANKYLSCERGLIPLRDFFAFALDEEGETSNVGVKEFVANLVKNEDRNKPLSDSKILELIKEEFKVDIGRRTITKYRKHLNIASSTDRKKLYELEG