wanglab/gogpt-training-data huggingface dataset:
Protein: 5' exonuclease Apollo (EC 3.1.-.-) (Beta-lactamase DCLRE1B) (EC 3.5.2.6) (DNA cross-link repair 1B protein) (SNM1 homolog B) (SNMIB) (hSNM1B) (Q9H816)
Organism: Homo sapiens (Human)
Function: 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint. Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin. Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem).
Subcellular location: Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.
Interaction partners:
- Telomeric repeat-binding factor 2
- TERF1-interacting nuclear factor 2
- Telomeric repeat-binding factor 1
- Structure-specific endonuclease subunit SLX4
- Telomeric repeat-binding factor 2-interacting protein 1
- Protection of telomeres protein 1
- Structure-specific endonuclease subunit MUS81
- Fanconi anemia group D2 protein
- Fanconi anemia group M protein
- DNA-dependent protein kinase catalytic subunit
Sequence:
MNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHRHLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHCPGSVMFLFEGYFGTILYTGDFRYTPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQEAAHQIVQLIRKHPQHNIKIGLYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTHPTIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKKQLFPDLYSKEWNKAVPFCESQKRVTMLTAPLGFSVHLRSTDEEFISQKTREEIGLGSPLVPMGDDDGGPEATGNQSAWMGHGSPLSHSSKGTPLLATEFRGLALKYLLTPVNFFQAGYSSRRFDQQVEKYHKPC
Protein: Nuclear pore complex protein (Q54N06)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|RuleBase:RU365072}. Nucleus membrane {ECO:0000256|RuleBase:RU365072}.
Interaction partners:
- Nuclear pore protein
- Nuclear pore complex protein nup43
- Nucleoporin 133
- Nuclear pore complex protein nup85
- Uncharacterized protein
- Protein SEC13 homolog
- Uncharacterized protein
- Nuclear pore protein
- Uncharacterized protein
- Nucleoporin 155
Sequence:
MSENFKWNLGNNLNSNNNDDFFSTQPFNNNNKFDFSILPDDNNEDEFSGIVNNNNNMNNNNTLVKGDGGIFGNTQINFNNNNNNNNQFGNSLFGNTINNNNNNMEVNNDNDNNNNEQEFEMDNQQLQNNQMEMEEDENQFNNIFNDKSRTDDTIYHNTLEYELQPKLNDDPHLIPIELSDTFLKLSQAKINSINDDESNKLFYMQNNRKQKEQQLKNYQMEKDTWSILKKLYEYRDIQRSIDQKEKIDISQPNQVQVYNYLIKKDHKLRENLILLEWLEEMSSQVELNDNDAVFWEYTLIKLKKSNSITMLTNNQMVSELDPDAMSRQNKPIDKDDEKNQSRFLKTVWSFLRAGDRVGAAEYCTNVGQFWRAQTLIGLNYYQGEHSIGNPYFNLWKSNCLNISKNSNDQYERAIYGLLCGNLEATLPIQKNWYDYFWCYLRVLYDESLYRELKPYRSPLSIEEDIDSPPSTCISQINTPKDILEILKNNTSQIEIKNQSENPYHQIQELIIADDYSILFNSLPNLLLKNKTPEFNRFAVLLILFFRKREQYELISTSEDCPENIVINEYVQHLINSQQYELVALYTSLLNNESLQVDVYSRFLVNIIDPNQRQQLLVLAEKFGLNTQEIAQSVVKTITSGSINTTSNSFENLEFTGFATTINKNKQPKNKSTTTTKASTTETTTNTNTTTTPNLTNTIINQDSSITTQDDLVKINSIQWLCFEKQLLIKAILQSNLLLRDFISLNKYGAASELLKSLPKDIVMIAKQQSPLNESDTNNIIKEFRDWENYITANIRINLWLQNYSNQPKISNYLPQSLNNNNNYINNNNNSFNNIINNSIINSSIAFRLRGNESYAEKLDIERRKKEYDDVYGQWNQNNINFGKEAIVSIRSIIKTGWLCPLENQIGLFSEDDQSGHEVTLIRKKCIPSLFKSLYTILVGIGSIQKSSQLCNQIANERFRWYSIFSKKELQEILQLVRESSIKLLN
Protein: Beta-defensin 6 (BD-6) (mBD-6) (Defensin, beta 6) (Q91VD6)
Organism: Mus musculus (Mouse)
Function: Has potent antibacterial activity against E.coli (ATCC 25922).
Subcellular location: Secreted.
Interaction partners:
Sequence:
MKIHYLLFAFILVMLSPLAAFSQLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK
Protein: Misshapen, isoform B (Misshapen, isoform I) (Q7KV90)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPDDDDQAGDRTLIMKRNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEYQAAISSSVHSTPSKSFIASSGSGGLGLGGGTVVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSITNLLHKSASSSSANLHHLTPCSSTSSASISNPLPPHAYALQQKQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW
Protein: Alpha/beta hydrolase fold-3 domain-containing protein (A0A1D8PNU8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MNIYIYIYIYIKKSILISITISVPFLFHFSFYKKLTYFILFYFILFHFISLPIMLTFKGLLLILLLPSRLLSFIIKYPFIKGIPGKYQHNFSKSLFIKLCRLIQLLPVSDKGTLNFISTNFLLNKIMKLYHTRHFLGELNNFGKKFDDQSYWIHESPNRNRNKNKSDDPIIVYLHGGSYYFDNSLNQMESLIGIYQLLQNTTTITTTTTTNDDRTSVERKKNLSILVLDYKLASKGYKMPYQLNQLISTYKNLIYQGNTNLILMGDSAGGNLAITFLQHLRLTNNNNNNNNNSPANLPYPKSLILISPWCKIVPEISDYTKGHSMYDNNQYDIIEWKAVKKLIDNTSPLIRDDLSPQNLIISPGNLPYNIDDWIDIDTLQKSNYSTFVIMGEYETLRDDILNWCQYAVNSTLSSPIKHTQGIFDKNIHQFVSTKNDGAYVKCIIEPKGIHDASMIFENDILKEFQKHTTMNLQTINKDKYFGIYQIVEFLNEIL
Protein: Pre-mRNA-splicing factor cwf17 (Complexed with cdc5 protein 17) (O94620)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-splicing factor cwf2
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor spp42
- Pre-mRNA-splicing factor prp1
- Pre-mRNA-splicing factor brr2
- Pre-mRNA-splicing factor cwf7
- Pre-mRNA-splicing factor cwf14
Sequence:
MDKRKESESATNGHLVKRIRIQDSSLITEGSVLQRTSDLNVPNLQMFGHTAEVLVARFDPSGSYFASGGMDRQILLWNVFGDVKNYGVLNGCKGAITDLQWSRDSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTMKVWDSRSKDCIKTIEEKYPLTAVAIAQQGTQVFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVKPFASAQRQLQIFEGAIHGQEHNLLGVAWSRNSRFVGAGSSDKNVYVWSATGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSDRTIFLGELN
Protein: Probable metallopeptidase (Q9HVS3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Type VI lipase immunity protein Tli3
- Type VI lipase adapter protein Tla3
- Type VI secretion system spike protein VgrG2b
- Probable transcriptional regulator
Sequence:
MTVGVGGSTPAQALERLRNMMDGAQPIGLASYRARIAAAQAWMGEHGIAAAYLHAGSNLRYFSGVQWHPSERLVGALLPAEGALEYLAPAFEEGTVRDFQVVDGAIHTWEEHQDPYRLLLDRLEALGVGERSTVALCPSLPFGMFERLRQQAPGRNFVSAAPLIDQGRMRKSAEELALMQRAKDMTLEVQKAAASILREGISTTEVAEFIHQAHRKVGAPGSTFCIVLFGAASAFPHGVKHAQVLKDGDMVLIDTGCQVHGYQSDITRSYVFGTPSARQREFWGMERDAQLAAFEAARLGQPCEAVDAAARRSLEANGLGPDYRLPGLPHRTGHGIGMDVHEGPYLVRGDRTPLDVGMCFSNEPMICVPGEFGIRLEDHFYMTKEGPRWFTQPSPSIDDPFGLGG
Protein: Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit) (Q9Z258)
Organism: Rattus norvegicus (Rat)
Function: Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro).
Subcellular location: Cell membrane {ECO:0000269|PubMed:12442315, ECO:0000269|PubMed:16045448, ECO:0000269|PubMed:36898835}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5JUK3}.
Interaction partners:
- Calcium-activated potassium channel subunit beta-4
Sequence:
MARAKLPRSPSEGKAGPGDTPAGSAAPEEPHGLSPLLPTRGGGSVGSDVGQRLHVEDFSLDSSLSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPDQGIGCWGCTKYNYTFNGSSSEFHWAPILWVERKMALWVIQVIVATISFLETMLLIYLSYKGNIWEQIFHVSFVLEMINTLPFIITVFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAGGNLNLLTSFYFCIVTFSTVGFGDVTPKIWPSQLLVVILICVTLVVLPLQFEELVYLWMERQKSGGNYSRHRARTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPSEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLKREENKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEKQKRRGLAGQALYEGPSRLPVHSIIASMGTVAMDLQNTDCRPSQGGSGGGGGKLTLPTENGSGSRRPSIAPVLELADSSALLPCDLLSDQSEDEVTPSDDEGLSVVEYVKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRRELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKQERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKVTEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTECHVFSSEPHDLRAQSQISVNMEDCEDTREAKGPWGTRAASGGGSTHGRHGGSADPVEHPLLRRKSLQWARKLSRKSSKQAGKAPMTTDWITQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVMNRVNLGYLQDEMNDHHQNTLSYVLINPPPDTRLEPNDIVYLIRSDPLAHVTSSSQSRKSSCSNKLSSCNPETRDETQL
Protein: Squamosa promoter-binding-like protein 5 (Q9S758)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' of AP1 promoter. Promotes both vegetative phase change and flowering.
Subcellular location: Nucleus {ECO:0000269|PubMed:16095614}. Cytoplasm {ECO:0000269|PubMed:16095614}. Note=Mostly located in nucleus.
Interaction partners:
- MADS-box protein SOC1
- Agamous-like MADS-box protein AGL8
- Protein LEAFY
- AP2-like ethylene-responsive transcription factor SNZ
- Ethylene-responsive transcription factor RAP2-7
- Cleavage and polyadenylation specificity factor
- AP2-like ethylene-responsive transcription factor SMZ
- AP2-like ethylene-responsive transcription factor TOE2
- Protein TWIN SISTER of FT
- AP2-like ethylene-responsive transcription factor TOE3
Sequence:
MEGQRTQRRGYLKDKATVSNLVEEEMENGMDGEEEDGGDEDKRKKVMERVRGPSTDRVPSRLCQVDRCTVNLTEAKQYYRRHRVCEVHAKASAATVAGVRQRFCQQCSRFHELPEFDEAKRSCRRRLAGHNERRRKISGDSFGEGSGRRGFSGQLIQTQERNRVDRKLPMTNSSFKRPQIR
Protein: TRAF2 and NCK interacting kinase a (EC 2.7.11.1) (Q7SY42)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MASDSPARSLDEIDLSTLRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKCMDVTGEEEEEIKAEINMLKKYSHHRNIATYYGAFIKKNPPGVDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEDWTAYISREILRGLTHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVSRRNTFIGTPYWMAPEVIACDENPDATYDYKSDLWSLGITALEMAEGAPPLCELHPMRALFLIPRNAPPRLKSKKWTKRFHSFIESCLVKNHNMRPGTDQLLKHPFIRDMANERTIRIQLKDHIDRTRKKRGERDETEYEYSGSEEEEEAMLEIGEPSSIINIPGESTLRRDFLRLQVANKERSDALRRQQLEQQQNEGHKHQLLAERQKRIEEQKEQRRRLEEQQRREREARKQQEQRHRYEELRREEERRQAEREQEYKRKQVEEQRQADRLQRQLQQERAYLVSLQQQQQQQQQDSRPEEKKQLYHYKDAVNPSDKPAWAKKVEERSKLNRQSSPALQHKVANRISDPSLPPRSESFSSGGMQPARTPPMHRPVEPQMAHLVPVRSHSSSMSVSQSLHDQSAKGVSAFQESLVSNRPEMPRQNSDPTSEMPPPAPRMASHEEKPDRSSPWLREDAVPPKLSGTTQVPQRTTSISPALARKNSPGNGESSGGGRSASQLIRTSNPDLRRTELSLDVALQRTSSNSSSSSSTPSSQGGSQPGSSERNQPRGSGKSEGSPVALQETSKPIQEEGRELSKPSRPADLTALAKELRELRIDEVSRPPLKLTDYSSSSEDSDSSEDEDGTVGHDGTVSVSDIPRIMPSVQGNNESFTSSHDDSLTDSYNDESKDGTLRMRENNERQRLGHGESNGFAGHGNLPDLLQQSHSPSGTPTGLNSQDLDSMDEFGLGGGSKASFTPFVDPRVYQTSPTDDNDESSAAAMFANELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLITRRRFQQMDVLEGLNVLVTISGKRNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGELEGCIHYKVVIYERIKFLVIALKNSVEIYAWAPKPYHKFMAFKSFTELQHRPQLVDLTVEEGQRLKVIYGSSVGFHVIDVDSGSPYDIYIPSHIQSTVTPHAIVVLPKTDGMEMLLRYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSLMNW
Protein: Small ribosomal subunit protein uS11c (30S ribosomal protein S11, chloroplastic) (P0C464)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS8c
- Small ribosomal subunit protein uS14c
- Os02g0102400 protein
- Os08g0513300 protein
- Small ribosomal subunit protein uS2c
- Os01g0220300 protein
- Small ribosomal subunit protein uS9c
- Os07g0658200 protein
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein mL46
Sequence:
MTKAIPKIGSRRKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
Protein: G protein-coupled receptor kinase 3 (EC 2.7.11.15) (Beta-adrenergic receptor kinase 2) (Beta-ARK-2) (Q3UYH7)
Organism: Mus musculus (Mouse)
Function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Subcellular location: Postsynapse {ECO:0000250|UniProtKB:P26819}. Presynapse {ECO:0000250|UniProtKB:P26819}.
Interaction partners:
- Beta-arrestin-2
- Protein smoothened
- Beta-arrestin-1
- Mu-type opioid receptor
- Beta-adrenergic receptor kinase 1
- Casein kinase I isoform epsilon
- Casein kinase I isoform gamma-3
- Casein kinase I isoform gamma-1
- Casein kinase I isoform delta
- S-arrestin
Sequence:
MADLEAVLADVSYLMAMEKSKTAPAARASKKVVLPEPSIRSVMQRYLAERNEITFDKIFNQKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKLDNEEDRLRRSRQMYDAYIMRELLSSTHQFSKQAVEHVQSHLSKKQVTATLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLSMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFFKGIDWQHVYLRKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQDLYKNFPLVISERWQQEVVETIYDAVNADTDKIEARRKAKNKQLGQEEDYAMGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIMSVEETQIKDRKCILLRIKGGKQFVLQCESDPEFAQWLKELTCTFNEAQRLLRRAPKFLNKPRAAILEFSKPPLCHRNSSGL
Protein: Eyegone (O77238)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MSQHRLLEFSRFGGLRGYDIAQHMLTQQGAVSKLLGSLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLISEGVCTNATAPSVSSINRILRNRAAERVATEFARTAAYGLYPPPPHPYGSFTWHPAGNVPGGQGVPPPPPPSALWSVAAPTLANLPPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENRHIDSDYLDDDDEPKFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMNLLKRQRSSPANPLHSQQSNDAPASSPTPSNHSSASTSAPVAPVPPPQQPLPLCGDHSPQGPPPSVLLHPLHGPPGGHHHHHPLHLPTHPAALQLLSHYHQQQQQQQQQQHQQQQQQHHQQQQQLSPSGCNPAANHLSMGGERSAFRSLVSSPSAPAFLGLARQYAVAASLTVAEEQRSRLHYSAGGLGSGGEGTGPNTNTTQSGGSTMTVDNSSSDSDEEINVHDDSRW
Protein: Cell shape-determining protein MreB (Q9WZ57)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02207}. Note=Membrane-associated. {ECO:0000256|HAMAP-Rule:MF_02207}.
Interaction partners:
Sequence:
MLRKDIGIDLGTANTLVFLRGKGIVVNEPSVIAIDSTTGEILKVGLEAKNMIGKTPATIKAIRPMRDGVIADYTVALVMLRYFINKAKGGMNLFKPRVVIGVPIGITDVERRAILDAGLEAGASKVFLIEEPMAAAIGSNLNVEEPSGNMVVDIGGGTTEVAVISLGSIVTWESIRIAGDEMDEAIVQYVRETYRVAIGERTAERVKIEIGNVFPSKENDELETTVSGIDLSTGLPRKLTLKGGEVREALRSVVVAIVESVRTTLEKTPPELVSDIIERGIFLTGGGSLLRGLDTLLQKETGISVIRSEEPLTAVAKGAGMVLDKVNILKKLQGAG
Protein: Olfactory receptor 1D4 (Olfactory receptor 17-30) (OR17-30) (P47884)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MDGDNQSENSQFLLLGISESPEQQQILFWMFLSMYLVTVLGNVLIILAISSDSHLHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVAICCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPREIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTLLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLHTYSMKDSVATVMYAVLTPMMNPFIYSLRNKDMHGAPGRVLWRPFQRP
Protein: HSPC060 (Q9NZX6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGEDEKGGKTDQSESLMGTLKRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDLRAQRPIRSTSLRSHHYRPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQSETTCQEQANSLKSSASHNGDLHLHLYEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSYCLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSPRAGHDDVPPLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCI
Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta) (No receptor potential A protein) (Phosphoinositide phospholipase C) (Phosphoinositide phospholipase C-beta) (P13217)
Organism: Drosophila melanogaster (Fruit fly)
Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway. Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection.
Interaction partners:
- Inactivation-no-after-potential D protein
- Opsin Rh1
- G protein alpha q subunit subunit alpha)
- Eye-specific diacylglycerol kinase
- Protein kinase C, eye isozyme
- Neither inactivation nor afterpotential protein C
- Transient-receptor-potential-like protein
- Diacylglycerol kinase
- Diacylglycerol kinase
- Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform E
Sequence:
MTKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDASAGKPPEAAAAPAPAPEAAAAAEGAAEGGGGAEAEAAAANYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQSGGAARDAGKAKEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEEAYKTQGKTEFYA
Protein: Hydroxylamine oxidoreductase (EC 1.7.2.9) (Q1PX48)
Organism: Kuenenia stuttgartiensis
Subcellular location: Anammoxosome {ECO:0000269|PubMed:25962914}. Note=Preferentially, localizes in the proximity of the anammoxosome membrane. {ECO:0000269|PubMed:25962914}.
Interaction partners:
Sequence:
MFEIFKKPLSRIVGATFAFAGVTLLACAMENGVAMAEGPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEIHH
Protein: GTPase Era, mitochondrial (ERA-like protein 1) (Q09523)
Organism: Caenorhabditis elegans
Function: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly (By similarity). Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region (By similarity). May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity). May play a role in positively regulating mitochondrial function. Plays a role in fertility.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:O75616}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:O75616}; Peripheral membrane protein {ECO:0000305}. Note=Localizes on the matrix side on the mitochondrial inner membrane. {ECO:0000250|UniProtKB:O75616}.
Interaction partners:
- Mitochondrial Ribosomal Protein, Small
- Small ribosomal subunit protein bS16m
- G domain-containing protein
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein mS26
Sequence:
MIIKRLNFSCRLFSTASTSTSYEKTPIQPATKCLQLAVIGAPNVGKSLLTNSLIRCPLSAVSSKMDTTTRNISASICSDSTQLVFVDSPGAVSTSHVRQTMKKTSATSGDRVLQDPERALQRAQHVLVVQDSTAPGAYIHHRVLHMLHRYSHVPSILVMNKIDLVMRRSDLLPLVEILTNGQLSDNQQISTKPAQIGRLGKSLSTNIQSSSSFKPSDEKWQSQFRELIQKPTWKCSYSETRSLFRTICGWSGFERVFFVSSLNGEGIDELRDHLMSISPQGEWKMQDGMPTGESAQQLCIDSIRAAVLDTTPSDVAYTVQIRISEWEEQGEVLQIVGEIRCQKPRDGSLIIGKGGKRISEIGRRVNEHLHSLFQRQLYARLIVTHNGKLITQSK
Protein: Type II iodothyronine deiodinase (EC 1.21.99.4) (5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase) (P70551)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q92813}; Single-pass type III membrane protein {ECO:0000250|UniProtKB:Q92813}.
Interaction partners:
- Type I iodothyronine deiodinase
- Lipid transferase CIDEA
- PR/SET domain 16.
- Mitochondrial brown fat uncoupling protein 1
Sequence:
MGLLSVDLLITLQILPVFFSNCLFLALYDSVILLKHVALLLSRSKSTRGEWRRMLTSEGLRCVWNSFLLDAYKQVKLGEDAPNSSVVHVSNPEAGNNCASEKTADGAECHLLDFASAERPLVVNFGSATUPPFTRQLPAFRQLVEEFSSVADFLLVYIDEAHPSDGWAVPGDSSMSFEVKKHRNQEDRCAAAHQLLERFSLPPQCQVVADRMDNNANVAYGVAFERVCIVQRRKIAYLGGKGPFSYNLQEVRSWLEKNFSKRUILD
Protein: Protein RKD4 (AtRKD4) (RWP-RK domain-containing protein 4) (Q9LVU8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription factor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00852}.
Interaction partners:
- AP2-like ethylene-responsive transcription factor BBM
- Protein WUSCHEL
- Agamous-like MADS-box protein AGL15
- Probable WRKY transcription factor 2
- WUSCHEL-related homeobox 8
- WUSCHEL-related homeobox 9
- WUSCHEL-related homeobox 2
- Nuclear transcription factor Y subunit B-6
- B3 domain-containing transcription factor LEC2
Sequence:
MSSSKHSSVFNYSALFLSLFLQQMDQNSLHHLDSPKIENEYEPDSLYDMLDKLPPLDSLLDMEDLKPNAGLHFQFHYNSFEDFFENIEVDNTIPSDIHLLTQEPYFSSDSSSSSPLAIQNDGLISNVKVEKVTVKKKRNLKKKRQDKLEMSEIKQFFDRPIMKAAKELNVGLTVLKKRCRELGIYRWPHRKLKSLNSLIKNLKNVGMEEEVKNLEEHRFLIEQEPDAELSDGTKKLRQACFKANYKRRKSLGDDYY