wanglab/gogpt-training-data huggingface dataset:
Protein: 5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma3) (AMPK subunit gamma-3) (Q8BGM7)
Organism: Mus musculus (Mouse)
Function: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. AMPK also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. The AMPK gamma3 subunit is a non-catalytic subunit with a regulatory role in muscle energy metabolism. It mediates binding to AMP, ADP and ATP, leading to AMPK activation or inhibition: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Interaction partners:
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
- 5'-AMP-activated protein kinase subunit beta-2
- 5'-AMP-activated protein kinase subunit beta-1
- Calcium/calmodulin-dependent protein kinase kinase 2
- Serine/threonine-protein kinase STK11
- 5'-AMP-activated protein kinase subunit gamma-1
- 5'-AMP-activated protein kinase subunit gamma-2
- TBC1 domain family member 1
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
Sequence:
MEPELEHTLPGTLTWSHSGGPESQEMDFLEQGENSWPSPAVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGEGAQSRPAAESTRQEATFPKATPLAQAVPLAEAETSPTGWDLLLPDCAASAGGSSTGDLELTIEFPAPEAWDCELEGLGKDRPRPGPSPQAPLLGLSWDDELQKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEEHKIETWREIYLQGCFKPLVSISPNDSLFEAVYALIKNRIHRLPVLDPVSGTVLYILTHKRLLKFLHIFGALLPRPSFLCRTIQDLGIGTFRDLAVVLETAPVLTALDIFVDRRVSALPVVNESGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALSA
Protein: Filamin binding LIM protein 1 (E7EWE8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE
Protein: Large ribosomal subunit protein bL32c (50S ribosomal protein L32, chloroplastic) (Q6ENA9)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein bL20c
- Small ribosomal subunit protein uS11c
- 50S ribosomal protein L22
- Large ribosomal subunit protein uL22c
- Large ribosomal subunit protein bL33c
- Small ribosomal subunit protein bS16c
- 60S ribosomal protein L17
- 50S ribosomal protein 5
- Small ribosomal subunit protein uS8c
- Large ribosomal subunit protein uL22c
Sequence:
MAVPKKRTSMSKKRIRKNLWKKKTYFSIVQSYSLAKSRSFSGVSEHPKPKGFSRQQTNK
Protein: Probable high-affinity hexose transporter ght7 (Hexose transporter 7) (Q8TFG1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- SNF1-like protein kinase ssp2
- Putative uncharacterized protein SPCC794.16.
- Putative uncharacterized protein C32H8.15
Sequence:
MRDFQSRFADRYNQITNSYSYSSSRQGLITGMVNVGSFFGCLLSSPVADKIGKRLSIIVWTTVYLIGIIIQVTTVPSWVQILVAKIWTGLSIGALSVITPGYQSEVAPAIMRGAIVTTYQLFITLGIFIAACINMGTHKYSHGTTAQWRISIGINLLWGIITLVGIIFLPESPRYLIAIGKDDEALKIMCYNNDLPLEHEIIQTEYHTIKSDCDAELAGGPARWPEIFNANIRYRTFLGMAVMMFQQLTGANYYFYYGTQVFRGTGMDSPYLAALIPDAVNCGCTFGAIFVLEFFGRRSPLIVGGIWQYICFFIYAAVGDRALYHKNGTSNHRAGAVMIVFSCLFIFSFSQTWAPAAYVIVGESYPVRYRSKCAAVATSANWFWNFLISFFTPFITNSIGFKYGYIFASCNLTGAAIIFLFVHETKGRTLEEINTMYASNLKPWMPHPEGYREFGREQNNATLKSHIGLNGETTELIENTDNQGDSGSFQTSTPDDSRPEQNQASATYIRPDKREPRL
Protein: Cta6p (A0A1D8PMS5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MSRDGTFSYIHLDDPNKVLYIERWKDEPITYDDIETSNLVEAAVNVYPQLFAEEEEDDGILNFPSQQFGSKLYKNRRSIKQKRWMDLNIESFKSDNKNVVDKTLVPPVAGDPDLAEFLSNGYNKEELSVLQLSPGNNTVLHNSDMSLNSTSDYVGNSNNTFINMRSNSTSHQQPSQQQQQQQQQQSQFQTPRPGRVRQVSTDKFQTPVSRIMR
Protein: Epidermal growth factor receptor pathway substrate 15 (A0A8I5YC99)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAAAAQLSLTQLSSGNPVYEKYYRQVEAGNTGRVLALDAAAFLKKSGLPDLILGKIWDLADTDGKGVLNKQEFFIALRLVACAQNGLEVSLSSLNLAVPPPRFHDSSSPLLTSGTSVAELPWAVKSEDKAKYDAIFDSLSPVDGFLSGDKVKPVLLNSKLPVEILGRVWELSDIDHDGKLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGYVSGLEVRETFLKTGLPSTLLAHIWALCDTKNCGKLSKDQFALAFHLINQKLIKGIDPPHSLTPEMIPPSDKSSLQKNTIGSSPVADFSAIKELDTLNNEIIDLQREKNNVEQDLKEKEDTVRQRTTEAQDLQDEVQRESLNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAEITSQESQISTYEEELSKAREELSRLQQETAQLEESVESGKAQLEPLQQHLQDSQQEISSMQMRLAMKDLETDNNQSNWCSSPQSILVNGAADYCSLSTSSSETANLNEHAEGQNNLESEPIHPESSVRSSPEIAPSDVTDESEVVTAADIEKVSPRFDDDKHSKEEDPFNVESSSLTDAVADTNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDPFKGSDPFASDCFFKQTSTDPFATSSTDPFSASSNSSNTSVETWKHNDPFAPGGTVVAATDSATDPFASVFGNESFGDGFADFSTLSKVSNEDPFNPTISSSASSVVIPKPVLEETPSKSEDVPPALPPKTGTPTRPCPPPPGKRPINKLDSSDPFKLNDPFQPFPGNDSPKEKDPDMFCDPFTSSSTTANKEAEPSNFANFSAYPSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA
Protein: Class A basic helix-loop-helix protein 9 (bHLHa9) (Class B basic helix-loop-helix factor 42) (bHLHf42) (A3KNX5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor, which play a role in limb development. Is an essential player in the regulatory network governing transcription of genes implicated in limb morphogenesis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Trafficking regulator of GLUT4
- Ceramide synthase
- Fer3-like bHLH transcription factor.
Sequence:
MTPVSVCRFSMASRGSFTGSEFSEEEPDGSLQESELDSSDGLGGLNEPEERLIKKRSRPVRSKARRVAANVRERKRILDYNQAFNALRVALHHDLSGKRLSKIATLQRAINRISALSVFLTNNPPVGVAKPCGHLECQPGGLWAEAEPSMQNFLTWHQPLNQHLQTSIHRLSSEQHVFTGPACPPSPHYPCFSPDTQLYPAASVPSPPRYGRIGDVGAYQQGVWGGNHADGYGESLQTLPLPWHMGYLQDAGLQHCPNTLCYTQCKTVRAL
Protein: Small ribosomal subunit protein uS19 (40S ribosomal protein S15) (Q7JZW2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Large ribosomal subunit protein uL6
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein eL21
- Small ribosomal subunit protein eS10A
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL13
- 40S ribosomal protein S27
- 60S ribosomal protein L27
- Small ribosomal subunit protein uS14
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MADQVDENLKKKRTFKKFTYRGVDLDQLLDMPNNQLVELMHSRARRRFSRGLKRKPMALIKKLRKAKKEAPPNEKPEIVKTHLRNMIIVPEMTGSIIGVYNGKDFGQVEVKPEMIGHYLGEFALTYKPVKHGRPGIGATHSSRFIPLK
Protein: Evasin P1132 (V5GZ08)
Organism: Ixodes ricinus (Common tick) (Acarus ricinus)
Function: Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL5 and CXCL8.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MEVKTFAFLQIAVFIALGAQIFLAGTDALSDEDELFSVEYCGTNCTKQDTGSWTTCSGNCTCYHEDGKKVGLCLSTEYTDFTKFPKPTSEEIANARPLPKREKTLN
Protein: TIR domain-containing adapter molecule 1 (TICAM-1) (M0RA08)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle, autophagosome {ECO:0000256|PIRNR:PIRNR037744}. Cytoplasm, cytosol {ECO:0000256|PIRNR:PIRNR037744}. Mitochondrion {ECO:0000256|PIRNR:PIRNR037744}.
Interaction partners:
- 1-acylglycerol-3-phosphate O-acyltransferase ABHD5
- Heat shock cognate 71 kDa protein
- Hormone-sensitive lipase
- Rho-related BTB domain-containing protein 3
- Vesicle-associated membrane protein 3
- Patatin-like phospholipase domain-containing protein 2
- Rab9 effector protein with kelch motifs
- Cation-independent mannose-6-phosphate receptor
- Lipid transferase CIDEC
- 30 kDa adipocyte complement-related protein
Sequence:
MPKRTHLSQRSALSPSRILVAGDKAVHKTIGSEHVSIHPTLCGSRLHPPPSMTNPAPSLHSVFGILSALERDRLTCLKHKLGSLHPGSLESKLLHAMVLLALGQDTEARVSLESLKVNTAAQLVAGQWADMENTEDPEEPPDLSWTVARLYHLLAEENLCPASTRDVAYQVALRDLTSQGDHQLGQLQKEAWDRCSSHQGSLQPPSAAPAMTRSQPRPIDTSDWSWGHTLHSTGSTATLASHLEISQSPTLAFFSSHHGAHGPSKLCDKPLGTQEPQLVPEGCEEPDRSQPPPVQTSISLGLPHEIRVPEVALPILPDSLAAPNTSVHCPIECTEVSADSRSPLTSITESVGKQWPITSQRSPQFPVGDDVLPNSMSSSPPAQPPSSQASSVQPPLSSASSQSSCPAPPASTPPVSEHLETSDQKFYNFVVIHARADEHVALRIREKLETLGVPDGATFCEEFQVPGRGELHCLQDAIDHSGFMILLLTASFDCPLSLHQVNHALMNSLTQSGRQDCVIPLLPLECSQAQLSPDTTRLLHSIVWLDEHSPIFARKVANTFKAQKLQAQRERWKKEQEARTLKEQSTQLEAERQRVAAISAAYSAYVHGYTAWQTEMNRLGVAFGKDLSLGPPTPFPSWPGFPKPMPSHPQGCTPVSPYSPRQPPSSSLSQSFSPASSPAPQTPGPQPLIIHHAQMVQLGVNNHMWGHTGAQSSDDKTEFGETLDGPSDRGEPLS
Protein: Down syndrome cell adhesion molecule 1, isoform V (Q0E9I7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVAQYYDTDVNKAYVIRGNAAVLKCEIPSFVADFVSVVSWHTDQNEDFLPGSEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIGSKAPSVPTGVMVFQQQVPLLSTFAMLCQAQAFPVPVFRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMAPPKITPFSFGEEPANVEDSVSVTCLISTGDLPIDIEWFFNEYGISSYSGISVMKGGKRNSVLSIDSVQARHAGNYSCRAKNHAAAVNYTTDLIVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Protein transport protein sec16 (A0A3F2YNX0)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU364101}.
Interaction partners:
Sequence:
XETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYYSSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRYDPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIYRSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPTSPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGPLAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAHFCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLPSFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDPQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKAPGDLPAAGGPPSGAMPFYNPAQLAQACATSGSSRLGRIGQRKHLVLN
Protein: SNF1-related protein kinase regulatory subunit gamma-like PV42a (AtPV42a) (AKIN subunit gamma-like PV42a) (CBS domain-containing protein CBSCBS4) (Q9XI37)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays redundant role with PV42b in regulating male gametogenesis and pollen tube guidance.
Interaction partners:
- Sucrose nonfermenting 4-like protein
- CBS domain-containing protein CBSCBSPB3
- CBS domain-containing protein CBSX6
- SNF1-related protein kinase regulatory subunit beta-3
- CBS domain-containing protein CBSX5
- Seed dormancy control protein
- SNF1-related protein kinase regulatory subunit gamma-1
- Cytochrome P450, family 87, subfamily A, polypeptide 7
- Transcription initiation factor IIE subunit beta
- Cytochrome P450, family 87, subfamily A, polypeptide 6
Sequence:
MQEEKSKEDHSRLINVTAKDLTVRNRRLVEVPYTATLSHAMNTLVANSISALPVAAPPGHWIGAGGSMIMESDKQTGVVRKHYIGILTMLDILAHIAGEDSNLSDLDRKMSSQVSSIIGHCLEGLSLWTLNPNTSVLECMEVFSKGIHRALVPVESSIESNNTIAGVELIESASAYKMLTQMDLLRFLKDHHFDDLKTVLSRSISDLGAVNDSVYAITERTTVSNAINVMKGALLNAVPIVHAPDIAQEDHLQLVNGRHRKVIGTFSATDLKGCRLPELQTWLPLTALEFTEKTSGKEREVVSCGVESTMEEAIEKVVTRGVHRVWVMDQQGLLQGVVSLTDIIRSLRSTLS
Protein: Tudor domain-containing protein 7A (A6NAF9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Probably required during spermatogenesis (By similarity). Required for structural integrity of granules in primordial germ cells (PGCs).
Subcellular location: Cytoplasm. Note=Localizes to cytoplasmic RNA granules (By similarity). Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250}.
Interaction partners:
- Dead end protein 1
- Piwi-like protein 1
- ATP-dependent RNA helicase TDRD9
- Nanos homolog 1
- Piwi-like protein 2
- Nanos homolog 3
- Deleted in azoospermia-like
- Tudor domain-containing 12.
- Bucky ball
Sequence:
MSDVELVKKMLRAVLQSSKHGVAMARLQGDYRALTGEMIPFRKFGHDTLESFLRSIPGVVRLERSITGEVMCFAGVCEETAHIAQLVARQKNVKKTGCSKLLNFQMRARTSHLFSHNVKPRLSLRQPSNMTHPGRGSVTSFYSTQRKLYSNDLPSSRAPAWQMNRKSPVPEKTSVVPSKINTNIKTPLKKTSGTAAQQKPVNRADVELVQGRIKQLLQKYSSGVWLSKIPQLYKSMFQEELHIIQEVEKWTHICTVEKPGSNNIVDRLVYPVLEPVPKASPVPVKSPCKQSPNTALLKQPTLTQKTTRTFRTLAINIPQSTPKPQTPLSPTSPNSTMIDFTLSETPKTQSLSPITPPSTPPAHQPLTTELKQKLRQLLNKYSQGLWAHGLPQLFQEAFGCAFPQYVLEDLSLLADTCMVEYPMPDNRKRAILYTLPCQVQTQPRSRPPPLVLPCTSNPHVPPLIIPTADFHSVFVIEINSTNNVVVRFAGGGYSKSLEVMEEEMQNFYNNIGAGLCLLSPKIGQLVAVASSDGAMLRAQVHQLSEDKVKVYFLDHGFFDLVSRKTLFQLRDQFMTLPFQATTCQLAGLEPFSTDPVVLKTLQSLAVGRSLLAEIVEREDTPLVVLYDTSENDDVNVTAMCLKALQDKSMENPLQVNSVYTNVCVTNVCSDGSVYCQLPSRGQAKLKDIMDKIEAHFISQLTWELLVSRPFCGKVCLAKYKGKWARAEIINLHGSHVLDILFLDLGLPASLEVSELREIPPIFLKELITIPPQAIKCLLEDLNVDRAVWPPEAVLWLRETVHNKAPSCMKIVKLDETRTVHIYLFCGNEAQDIHDSVNRQLASCPFWKQDVYANKINKASELFLPDAGEPSGSSPAPSNALTLPPQLNLPLVGQNMDVFVSVACHPGHFVLQPWQDLYKLVVLMGEMVLFYNKQEVTTVDIQKNNVYAAKIDNNWHRVLVKGLLTNGLVSVYELDYGKYELINYTQLQPLIEEFRQLPFQGISAQLADVKKEVWCEEASMVFRNHVEKKPLVAQIESVEEGEWPWERKISVYLVDTTQENKDIWIHNIMKEFLDEISRDA
Protein: Calcium/calmodulin-dependent protein kinase IGb (F1QB46)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Calmodulin
- Calmodulin-like protein 4
- BRISC and BRCA1-A complex member 2
Sequence:
MGRKEGEYEWKKSTDNIQDVFDFMDVLGSGAFSEVFMVKERKTGKLFAMKCVKKKNKRDINLENEIAVLRKIKHENVVCLEDFYESRTHYYLVMQLVSGGELFDRILDRGMYSEMDASSVIRQVLEAVSYLHNNGIVHRDLKPENLLYYSPDENSKIMISDFGLSKMEDNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETETRLFSKIMKGQYEFDSPFWDDISESAKDFIRNMMQKNPKMRFNTEQALRHPWIIGKTARSQDIYHSVSEQMQKNFAKSKWKQAFNATVAINHMKKLQQAHSEACVRLKDSPRDVPEIKVIASSTPESVRKKLLSETPEPNGSMNVPCGSTEAKSQYHPMRVSHSETTHVGTLTIAEKGKHVYHSEPADLNGYAKRSSNRPGQNLQTGVCSVM
Protein: 2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (F4IWV2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2, mitochondrial
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1, mitochondrial
- Dihydrolipoyl dehydrogenase 1, mitochondrial
- Dihydrolipoyl dehydrogenase 2, chloroplastic
- Dihydrolipoyl dehydrogenase 1, chloroplastic
- Dihydrolipoyl dehydrogenase 2, mitochondrial
- Succinate--CoA ligase subunit alpha-1, mitochondrial
- Peroxisomal isocitrate dehydrogenase
- Isocitrate dehydrogenase, chloroplastic/mitochondrial
- Cytosolic isocitrate dehydrogenase
Sequence:
MVWFRAGSSVTKLAVRRILNQGASYATRTRSIPSQTRSFHSTICRPKAQSAPVPRAVPLSKLTDSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRNFVGQAATSPGISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLEQREIPEDLDLALYGFTEADLDREFFLGVWQMSGFMSENRPVQTLRSILTRLEQAYCGNIGFEYMHIADRDKCNWLREKIETPTPWRYNRERREVILDRLAWSTQFENFLATKWTTAKRFGLEGGESLIPGMKEMFDRAADLGVESIVIGMSHRGRLNVLGNVVRKPLRQIFSEFSGGIRPVDEVGYTGTGDVKYHLGTSYDRPTRGGKKIHLSLVANPSHLEAADSVVVGKTRAKQYYSNDLDRTKNLGILIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVVNNQVAFTTDPRAGRSSQYCTDVAKALSAPIFHVNGDDVEAVVHACELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIKNHPSTLQIYHKKLLECGEVSQQDIDRIQEKVNTILNEEFVASKDYLPKKRDWLSTNWAGFKSPEQISRVRNTGVKPEILKTVGKAISSLPENFKPHRAVKKVYEQRAQMIESGEGVDWALAEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLIMNQDPEMFTVSNSSLSEFGVLGFELGYSMESPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVMLLPHGYDGQGPEHSSARLERYLQMSDDNPYVIPDMEPTMRKQIQECNWQIVNATTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCSGKVYYELDDERKKVGATDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGAFSYISPRLWTAMRSVNRGDMEDIKYVGRGPSAATATGFYTFHVKEQAGLVQKAIGKEPIN
Protein: Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin) (P55288)
Organism: Mus musculus (Mouse)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for proper focal adhesion assembly. Involved in the regulation of cell migration.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Catenin beta-1
- Cadherin-2
- Junction plakoglobin
- Catenin alpha-1
- Catenin delta-1
- Cadherin-3
- Cadherin-1
- Catenin alpha-2
- Cadherin-13
- Cadherin-20
Sequence:
MKENYCLQAALVCLSMLYHSQAFALERRSHLHPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVAIRVLDVNDNAPKFAAPYEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLPPEIMHNPNFTVRDNRDNTAGVYARRGGFSRQKQDFYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS
Protein: Growth hormone (Q0QBD0)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLLLAFTLLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCLSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
Protein: Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2) (P35235)
Organism: Mus musculus (Mouse)
Function: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (By similarity). Dephosphorylates GAB1, ARHGAP35 and EGFR (By similarity). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity (By similarity). Dephosphorylates CDC73 (By similarity). Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification. Dephosphorylates tyrosine-phosphorylated NEDD9/CAS-L (By similarity).
Subcellular location: Cytoplasm.
Interaction partners:
- Epidermal growth factor receptor
- Son of sevenless homolog 1
- GRB2-associated-binding protein 1
- GRB2-associated-binding protein 2
- Growth factor receptor-bound protein 2
- Fibroblast growth factor receptor substrate 2
- Insulin receptor substrate 1
- Platelet endothelial cell adhesion molecule
- SHC-transforming protein 1
- Son of sevenless homolog 2
Sequence:
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR