wanglab/gogpt-training-data huggingface dataset:
Protein: Erythrocyte membrane protein 1, PfEMP1 (O96108)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MATGSGGDSSRDESVKDLFDRIGKKVYEKTEKIAKRYTTELHGDLSKATYPNDKHPEGSTENNPCKLQYDYNTNVTHGFGQEYPCETDIVERFSDTEGAQCDKKKIKDNSEGACAPYRRLHVCVRNLENINDYSKINNKHNLLVEVCLAAKYEGESITGRYPQHQETNPDTKSQLCTVLARSFADIGDIIRGKDLYRGGNTKEKKKRKKLEENLKTIFGHIYDELKNGKTNGEEELQKRYRGDKDNDFYQLREDWWDANRETVWKAITCNAGSYQYSQPTCGRGEIPYVTLSKCQCIAGEVPTYFDYVPQYLRWFEEWAEDFCRKKKKKIPNVKTNCRQVQRGKEKYCDRDGYNCDGTIRKQYIYRLDTDCTKCSLACKTFAEWIDNQKEQFDKQKQKYQNEISGGGGRRQKRSTHSTKEYEGYEKHFNEELRNEGKDVRSFLQLLSKEKICKERIQVGEETANYGNFENESNTFSHTEYCDRCPLCGVDCSSDNCRKKPDKSCDEQITDKEYPPENTTKIPKLTAEKRKTGILKKYEKFCKNSDGNNGGQIKKWECHYEKNDKDDGNGDINNCIQGDWKTSKNVYYPISYYSFFYGSIIDMLNESIEWRERLKSCINDAKLGKCRKGCKNPCECYKRWVEKKKDEWDKIKEFFRKQKDLLKDIAGMDAGELLEFYLENIFLEDMKNANGDPKVIEKFKEILGKENEEVQDPLKTKKTIDDFLEKELNEAKNCVEKNPDNECPKQKAPGDGAAPSDPPREDITHHDGEHSSDEDEEEEEEEEQQPPAEGTEQGEEKSESKEVVEQQETPQKDTEKTVPTTTPTVDVCDTVKTALADTGSLNAACSLKYVTGKNYGWRCIAPSGTTSGKDGAICVPPRTQELCLYYLKELSDTTQKGLREAFIKTAAQETYLLWQKYKEDKQNETASTELDIDDPQTQLNGGEIPEDFKRQMFYTFGDYRDLFLGRYIGNDLDKVNNNITAVFQNGDHIPNGQKTDRQRQEFWGTYGKDIWKGMLCALQEAGGKKTLTETYNYSNVTFNGHLTGTKLNEFASRPSFLRWMTEWGDQFCRERITQLQILKERCMVYQYNGDKGKDDKKEKCTEACTYYKEWLTNWQDNYKKQNQRYTEVKGTSPYKEDSDVKESKYAHGYLRKILKNIICTSGTDIAYCNCMEGTSTTDSSNNDNIPESLKYPPIEIEEGCTCKDPSPGEVIPEKKVPEPKVLPKPPKLPKRQPKERDFPTPALKNAMLSSTIMWSIGIGFATFTYFYLKKKTKSTIDLLRVINIPKSDYDIPTKLSPNRYIPYTSGKYRGKRYIYLEGDSGTDSGYTDHYSDITSSSESEYEELDINDIYAPRAPKYKTLIEVVLEPSGNNTTASGNNTPSDTQNDIQNDGIPSSKITDNEWNTLKDEFISQYLQSEQPNDVPNDYSSGDIPLNTQPNTLYFDNPDEKPFITSIHDRDLYSGEEYSYNVNMVNTNNDIPISGKNGTYSGIDLINDSLNSNNVDIYDEVLKRKENELFGTNHTKKNTSTNSVAKELCGDPIMNQLDLLHKWLDRHRDMCEKWNNKEEVLDKLKEEWNKDNNSGNINPSGNINPSGNTPPTSDIPSGKLSDTPSDNNIPSSNKTLNTDVSIQIHMDNPKPINQFTNMDTILEDLEKYNEPYYDVQDDIYYDVHDHDVSTAGSNAMDVPSKVQIEMDINTKLVKEKYPISDVWDI
Protein: Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein) (D4A7P2)
Organism: Rattus norvegicus (Rat)
Function: Involved in the development and maintenance of excitatory synapse in the nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
Subcellular location: Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein. Note=Localized to excitatory synapses.
Interaction partners:
- Neurexin-3
- Neurexin-2
- Neurexin-1
- Disks large homolog 4
- Neuroligin-1
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L1
- Cerebellin-1
- Adhesion G protein-coupled receptor L2
- Glutamate receptor 2
Sequence:
MGLHFKWPLGAPMLAAIYAMSVVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWSTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILSSLRSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTAMATTYRDPTTEYTKISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTRLHMSNMSDQGPYSEYEPTHEGPFIIINGYGQCKCQQLPYKECEV
Protein: Phosphomannomutase (EC 5.4.2.8) (H3BV55)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU361118}.
Interaction partners:
Sequence:
MDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
Protein: ATP synthase F(0) complex subunit j, mitochondrial (6.8 kDa mitochondrial proteolipid) (6.8 kDa mitochondrial proteolipid protein) (MLQ) (P14790)
Organism: Bos taurus (Bovine)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Minor subunit required to maintain the ATP synthase population in the mitochondria.
Subcellular location: Mitochondrion membrane {ECO:0000250|UniProtKB:P56378}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit d, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit F6, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase F
Sequence:
MLQSLIKKVWIPMKPYYTQAYQEIWVGTGLMAYIVYKIRSADKRSKALKASSAAPAHGHH
Protein: Vesicle-associated protein 1-2 (Plant VAP homolog 12) (AtPVA12) (VAMP-associated protein 1-2) [Cleaved into: Vesicle-associated protein 1-2, N-terminally processed] (Q9SHC8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Vesicle-associated protein that binds the oxysterol-binding protein ORP3A and allows its targeting to the ER.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19207211}; Single-pass type IV membrane protein {ECO:0000269|PubMed:19207211}; Cytoplasmic side {ECO:0000269|PubMed:19207211}.
Interaction partners:
- Oxysterol-binding protein-related protein 3A
- Oxysterol-binding protein-related protein 3B
- Calcium load-activated calcium channel
- Oxysterol-binding protein-related protein 4A
- Calcium-binding EF hand family protein
- Protein yippee-like At5g53940
- Arginine/serine-rich-like splicing factor
- AT1G11360 protein
- At5g57460
- Transducin/WD40 repeat-like superfamily protein
Sequence:
MSNELLTIDPVDLQFPFELKKQISCSLYLGNKTDNYVAFKVKTTNPKKYCVRPNTGVVHPRSSSEVLVTMQAQKEAPADLQCKDKFLLQCVVASPGATPKDVTHEMFSKEAGHRVEETKLRVVYVAPPRPPSPVREGSEEGSSPRASVSDNGNASDFTAAPRFSADRVDAQDNSSEARALVTKLTEEKNSAVQLNNRLQQELDQLRRESKRSKSGGIPFMYVLLVGLIGLILGYIMKRT
Protein: Hsp70-Hsp90 organizing protein 3 (AtHop3) (Q9STH1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates the association of the molecular chaperones HSP70 and HSP90. Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting (By similarity). Involved in acclimation to heat.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Heat shock 70 kDa protein 4
- Heat shock protein 90-1
- Heat shock protein 90-2
- Heat shock protein 90-4
- Heat shock 70 kDa protein 16
- Heat shock 70 kDa protein 8
- Fes1A
- Heat shock 70 kDa protein 3
- Protein ENHANCER OF LHP1 1
- Heat shock 70 kDa protein 17
Sequence:
MAEEAKSKGNAAFSSGDYATAITHFTEAINLSPTNHILYSNRSASYASLHRYEEALSDAKKTIELKPDWSKGYSRLGAAFIGLSKFDEAVDSYKKGLEIDPSNEMLKSGLADASRSRVSSKSNPFVDAFQGKEMWEKLTADPGTRVYLEQDDFVKTMKEIQRNPNNLNLYMKDKRVMKALGVLLNVKFGGSSGEDTEMKEADERKEPEPEMEPMELTEEERQKKERKEKALKEKGEGNVAYKKKDFGRAVEHYTKAMELDDEDISYLTNRAAVYLEMGKYEECIEDCDKAVERGRELRSDFKMIARALTRKGSALVKMARCSKDFEPAIETFQKALTEHRNPDTLKKLNDAEKVKKELEQQEYFDPTIAEEEREKGNGFFKEQKYPEAVKHYSEAIKRNPNDVRAYSNRAACYTKLGALPEGLKDAEKCIELDPSFTKGYSRKGAIQFFMKEYDKAMETYQEGLKHDPKNQEFLDGVRRCVEQINKASRGDLTPEELKERQAKAMQDPEVQNILSDPVMRQVLVDFQENPKAAQEHMKNPMVMNKIQKLVSAGIVQVR
Protein: Zinc finger protein tra-4 (PLZF-like protein tra-4) (Q20709)
Organism: Caenorhabditis elegans
Function: Probable transcription factor. Promotes normal hermaphrodite (XX) development, in concert with histone deacetylase hda-1 and nasp-1, perhaps as components of a complex. May cooperate with transcription factor tra-1 to repress male-specific genes in hermaphrodites. Synthetic multivulva (synMuv) class B protein, required to repress the induction of vulval development by let-60 Ras signaling.
Subcellular location: Nucleus {ECO:0000269|PubMed:17011494}.
Interaction partners:
- Protein NASP homolog 1
- RNA cytidine acetyltransferase
Sequence:
MDDPNQCTIKQEDSITRPRPTEAPTIQNLKQEPAIEEGSSSTMDNMLMLTIDTNQANWQGTYDDDEMDLNNKTDLIPLLETEKTTINEDELYDDEEDDDDDEEIKKGIGFELLAQALGMSAKVPVEKEEPEKERAKLSGVGEFMKQIRGEIKPIQKERIVLDELGFRVRDPSKFPPCRIAEVQQTLTLADHQDGIDLPPPNAPTDVRIVRKLIRQKMVRCKKCKNRFIEKNIYERHLRDKHPDLYEEYIREQEEEVELQRLEEIEANRIEELQTGGFIPPENEISQPSEDPNYIPLPGENNGGLVPRFDYYGRIKQLKRPYKKKVSPQCPFCDKRFRNEFSLKKHFAKKHEEMVEFQQCLKCFKCVENDAEMANHDCELTYVCFECTPIRNLCTDNRLLNHRKKFHRGANSGFRCSFCNMKFLTPRKLRKHKKMSHVFTKTFQCHFCEEIFISEVAVMTHERMHTGIIKFECKVCDFRANRYTAMEEHKRDEHGYVCAICHERHAEYPEMKHHVYEEHGGYLAADEPTAYVETPRMWILYKGE
Protein: Acetyltransferase Pat (EC 2.3.1.-) (GCN5-related N-acetyltransferase) (GNAT) (Protein acetyltransferase) (Pat) (A0R3F9)
Organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Function: Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.
Interaction partners:
- Adenylate and Guanylate cyclase catalytic domain protein
- Shikimate 5-dehydrogenase
- Cyclase
- Adenylate and Guanylate cyclase catalytic domain protein
- NAD-dependent protein deacylase Sir2
- Polyketide synthase
- Universal stress protein family protein
- Putative ESX-1 scaffolding and assembly protein SaeC
- Phosphate acetyltransferase
- Mycocerosic acid synthase
Sequence:
MAELTEVRAADLAALEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFMLIESGRVQVSHAVADGPPIVLDIEPGLIIGEIALLRDAPRTATVVAAEPVIGWVGDRDAFDTILHLPGMFDRLVRIARQRLAAFITPIPVQVRTGEWFYLRPVLPGDVERTLNGPVEFSSETLYRRFQSVRKPTRALLEYLFEVDYADHFVWVMTEGALGPVIADARFVREGHNATMAEVAFTVGDDYQGRGIGSFLMGALIVSANYVGVQRFNARVLTDNMAMRKIMDRLGAVWVREDLGVVMTEVDVPPVDTVPFEPELIDQIRDATRKVIRAVSQ
Protein: CDGSH iron-sulfur domain-containing protein 2 (Endoplasmic reticulum intermembrane small protein) (MitoNEET-related 1 protein) (Miner1) (Nutrient-deprivation autophagy factor-1) (NAF-1) (Q8N5K1)
Organism: Homo sapiens (Human)
Function: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum. However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane.
Interaction partners:
- CDGSH iron-sulfur domain-containing protein 3, mitochondrial
- Wolframin
- Beclin-1
- Apoptosis regulator Bcl-2
- Calnexin
Sequence:
MVLESVARIVKVQLPAYLKRLPVPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV
Protein: Mitochondrial RNA binding complex 1 subunit (Q585T1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLLPTLERLLERCGRPIFSNVEDVRMVMASLLDISAYVDRASTKVIAKPLRRFCHKDPDTVASVMEAVPIDAAEPTHGRRAAMLLRCLPKHSCDEVIWERAVAATLAGLKSRKWDLHDYRVAMAHAGRGGRHAPALAAAAEEFVSSSARTASQSELPALLVILTSLPELKRSPCLQVAADRIVQLSEILSPAAIGQICASVNKVSFRHTAMAIALQEEAIRFAEESDLFSAVQLFSFICQQEKEAISPDAVKCLAERVIEGKDLDQETVSVLCRALRSIPRPHRPELLREIGEMMEFLGGEVKELLELPVAKGGLKGDVSAGDIQSFISKFLSLDGLLPADHDRPGTYMAAIVACVDYITERLEDIVSDENPPFSIIPHLLNINMEETRRCGQAIIREAAEQGIHFPTLQVFRFLLALGDHNMRDQRVYRHLRNEFAKTASDIPMIQLCAALKCFVRGLMQNVETQSLDEQVEHELEKEDMDAFLRFCVENLRRGFADGMEVKCVMAATESLYQLGYTSTEFYEQVARYLGSKCSSASASVNSSETATAVCLALGEDILDRHPDVHTFLLEVEKSGLKGEASLSPTEWMNKNDPANFITPLTEIQQEGWNIINRMVETRAADTEKLTALANEYVAILKSTRVDDLKYFFGVFEEKVFKQDRILKQCLDYLVESNAAVKLSATSIGAMLNSLAAIRFTYHRSVKQFMIAISTEQWSEMDASPLVKIVSAMAKLSLRLPQVLVHVGDRLLDVYTFLSPLDTALVINSLQSIGYGNDEVLMMLMRHAASSARRWDEVSLTLLFGASGVHRLLRNVEVAAPLLEQAAGKTSSPHLRQRIAASLRRSALPRALVQSSTSLLTGGAHEVVNNPPLQLV
Protein: Alpha- and gamma-adaptin-binding protein p34 (Q6PD74)
Organism: Homo sapiens (Human)
Function: May be involved in endocytic recycling of growth factor receptors such as EGFR.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:23000146, ECO:0000269|PubMed:23064416}.
Interaction partners:
- AP-2 complex subunit sigma
- AP-1 complex subunit sigma-3
- AP-1 complex subunit gamma-1
- AP-2 complex subunit alpha-2
- Coiled-coil domain-containing protein 32
- Keratin, type I cytoskeletal 9
Sequence:
MAAGVPCALVTSCSSVFSGDQLVQHILGTEDLIVEVTSNDAVRFYPWTIDNKYYSADINLCVVPNKFLVTAEIAESVQAFVVYFDSTQKSGLDSVSSWLPLAKAWLPEVMILVCDRVSEDGINRQKAQEWCIKHGFELVELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGSADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDVENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDEEH
Protein: Exported protein family 3 (Q8I2D6)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKHLLSLFKVSLFFLLIFKYSYKNIVKKGRQDNFNKSAITKYITSRALTENNKKCDIKDMHTSIFTGNKNPQIRGKKFKTKKEEEKQKDNTKEDNDNNMEKEMGDHMKDHMKEHMKENTKDDTKDDTKDHIDDHMKDHMKENTKDDTKDHTKDHMKDHMKDHMKDHTKDDTKDHMKDHTKDHMKDHMKENTKDDTKDDTKDDTKDDTKDDTKDDTKDDTKDDTKDDTKDDTKEYMDYILKHHNSLEDSIKEYYASTEPSVDDENKSFFKKIKLIMNILDDTHSDLLVNNHITNGGIFSPEFVPIGVLSSMTAACPLIGTVTLPYIARTINFMTKYKGEKIYTEQKSK
Protein: Phosphoribosylglycinamide formyltransferase 2 (P95197)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Phosphoribosylformylglycinamidine synthase subunit PurQ
- Phosphoribosylformylglycinamidine synthase subunit PurL
- Bifunctional purine biosynthesis protein PurH
- Phosphoribosylamine--glycine ligase
- Phosphoribosylglycinamide formyltransferase
- Phosphoribosylformylglycinamidine synthase subunit PurS
- Formyltetrahydrofolate deformylase
- Serine hydroxymethyltransferase 1
- Serine hydroxymethyltransferase 2
- Aminomethyltransferase
Sequence:
MIDGWTEEQHEPTVRHERPAAPQDVRRVMLLGSAEPSRELAIALQGLGAEVIAVDGYVGAPAHRIADQSVVVTMTDAEELTAVIRRLQPDFLVTVTAAVSVDALDAVEQADGECTELVPNARAVRCTADREGLRRLAADQLGLPTAPFWFVGSLGELQAVAVHAGFPLLVSPVAGVAGQGSSVVAGPNEVEPAWQRAAGHQVQPQTGGVSPRVCAESVVEIEFLVTMIVVCSQGPNGPLIEFCAPIGHRDADAGELESWQPQKLSTAALDAAKSIAARIVKALGGRGVFGVELMINGDEVYFADVTVCPAGSAWVTVRSQRLSVFELQARAILGLAVDTLMISPGAARVINPDHTAGRAAVGAAPPADALTGALGVPESDVVIFGRGLGVALATAPEVAIARERAREVASRLNVPDSRE
Protein: Polyadenylate-binding protein (PABP) (Poly(A)-binding protein) (P21187)
Organism: Drosophila melanogaster (Fruit fly)
Function: Binds the poly(A) tail of mRNA. Since it interacts with the cap-associating translation initiation factor eIF4G, it is likely that it functions by linking Atx2 to the cap-binding complex. Forms a complex with tyf and Atx2 which functions in adult circadian pacemaker neurons to sustain circadian rhythms likely by switching between activator and repressor modes of post-transcriptional regulation via interaction with Lsm12a or me31B, respectively. The activator complex (Atx2-tyf activator complex) activates the TYF-dependent translation of per to maintain 24 hour periodicity in circadian locomotor behaviors, whereas the repressor complex (Atx2-Not1 repressor complex) promotes Not1-dependent post-transcriptional gene silencing and supports high-amplitude circadian rhythms in a per-independent manner. In 0-1 hour embryos, forms a ribonucleoprotein complex (RNP) with me31B, eIF4E1, tral and cup which binds to various mRNAs including maternal mRNAs, and down-regulates their expression during the maternal-to-zygotic transition.
Interaction partners:
- Eukaryotic translation initiation factor 4E1
- Eukaryotic translation initiation factor 4G1, isoform B
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- Eukaryotic initiation factor 4A
- Eukaryotic translation release factor 3, isoform A
- Ataxin-2 homolog
Sequence:
MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFDLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKGYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDDEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQKKAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRSKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQIYQPNAASGFFVPTLPSNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGFQGTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITGQQTAAPNMQIPGAQIAGGAQQRTSNYKYTSNMRNPPVPQLHQTQPIPQQLQGKNSEKLIASLLANAKPQEQKQILGERLYPMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQVHRVTEPAN
Protein: Nucleolar complex protein 4 (U three protein 19) (U3 small nucleolar RNA-associated protein 19) (U3 snoRNA-associated protein 19) (Q06512)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm. Its subcellular location and association with pre-40S subunit are unaffected by RPS19 disruptions, suggesting it acts before the ribosomal protein.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12446671, ECO:0000269|PubMed:15590835, ECO:0000269|PubMed:16159874}.
Interaction partners:
- RNA cytidine acetyltransferase
- Small ribosomal subunit protein eS7A
- rRNA processing protein RCL1
- U3 small nucleolar RNA-associated protein MPP10
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 13
- Small ribosomal subunit protein uS4A
- Ribosomal RNA-processing protein 12
- Ribosome biogenesis protein ENP2
- rRNA-processing protein FCF1
Sequence:
MVLLISEIKDIAKRLTAAGDRKQYNSIIKLINELVIPENVTQLEEDETEKNLRFLVMSLFQIFRKLFSRGDLTLPSSKKSTLEKEQFVNWCRKVYEAFKTKLLAIISDIPFETSLGLDSLDVYLQLAELESTHFASEKGAPFFPNKTFRKLIIALWSSNMGEIEDVKSSGASENLIIVEFTEKYYTKFADIQYYFQSEFNQLLEDPAYQDLLLKNVGKWLALVNHDKHCSSVDADLEIFVPNPPQAIENESKFKSNFEKNWLSLLNGQLSLQQYKSILLILHKRIIPHFHTPTKLMDFLTDSYNLQSSNKNAGVVPILALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFFRLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKHPNCMIMLHNPAFISNPFQTPDQVANLKTLKENYVDPFDVHESDPELTHALDSSLWELASLMEHYHPNVATLAKIFAQPFKKLSYNMEDFLDWNYDSLLNAESSRKLKTLPTLEFEAFTNVFDNEDGDSEASSQGNVYLPGVAW
Protein: Arginine-glutamic acid dipeptide repeat protein (F4HZC9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVLLMGAENNLMEETTAVTEEDSYDDEFPCGDPQVEPRVGDEFQVDIPPMMSATKRAVFLSTPVALDDSSYSFLIGLPVQVMWIDKHRRGQGNGDDNVDMNQSLKSLRAKKSRCSAKIRGKSDKNSETKKQRSNLEAVPVIPSSSWEDLEVASFVLGLYTFGKNFTQVKNFMENKGIGEIMLFYYGKFYNSAKYHSWSESRKKRNRKCVFGRTLYSGWRQQQLLTRLMPSIPDEPQKQILVDVSKSFAEGTITLEKYVSAVKNLVGLRLLVDAVAIGKEKEDLTVPTSTPMKTKPWFTVSSKSSLVPGEGDYNSLTSAGIINQLTGCSRLSKARCNDIFWGAVWPRLLARGWHSQQPEDRGYFKSKDYIVFIVPGVKKFSRQELVKGDHYFDSVSDILTKVVSEPELLENETGGVAAELSSDKSDEESVPSDSLRHRYLRSPCSNRGTLGMKFTVVDTSLATGGKLCDLRNLNAECLVVSEPNVRLEVKDSPVLKNSLDSQNVEKSQVRPLDAKNQVDDPMRFTIIDTSVDHCEKSSGFRRWRYLPSDETKRGHVGADSGIKEEKTLEKVKDPSKRVIKHRSTPRAETNYHAVNSAPYLKRRRLSACISRESPVSKHIPGDDDTKMTVCLESEQQSICVVQQQTSTCEEMNQDKETVPLVEHMKLKSDQSKKTGTGPSSLLVEIQETTEIEPSGLNSNTGVDKNCSPEKISTSHEQKPNGLCSVSKSDKKRASNDLEQKQALELPSISGLNNRSSSNDLGTTQELGSSEQQHGQQNNTDGPRRQSTRKRPLTTRALEAMESDFLTTKRMKSTTKPEPRKRESSTKKKRSAKACNRNGSADLEHRREDRNIFIWKAPTSKPLDQIEDTKPRYLLNEARTESKTLDRIQESRPVLTEYRKLPPIVLKLPFRRG
Protein: Protein ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)] (Q7Z4H4)
Organism: Homo sapiens (Human)
Function: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.
Subcellular location: Secreted {ECO:0000305|PubMed:14615490}.
Interaction partners:
- Calcitonin gene-related peptide type 1 receptor
- Receptor activity-modifying protein 3
- Receptor activity-modifying protein 1
- Pro-adrenomedullin
- Receptor activity-modifying protein 2
- Guanine nucleotide-binding protein G
- Islet amyloid polypeptide
- Inositol oxygenase
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
Sequence:
MARIPTAALGCISLLCLQLPGSLSRSLGGDPRPVKPREPPARSPSSSLQPRHPAPRPVVWKLHRALQAQRGAGLAPVMGQPLRDGGRQHSGPRRHSGPRRTQAQLLRVGCVLGTCQVQNLSHRLWQLMGPAGRQDSAPVDPSSPHSYG
Protein: Hydrophobic protein RCI2B (Low temperature and salt-responsive protein LTI6B) (Q9ZNS6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Aquaporin PIP2-1
- Putative F-box/kelch-repeat protein At4g22430
- Histone H2B.6
Sequence:
MSTATFVEIILAIILPPLGVFLKFGCKVEFWICLILTLFGYLPGILYALYIITK
Protein: Accessory gland-specific peptide 57Db (Male accessory gland secretory protein 57Db) (Q9VBL7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transferred from male to female during mating and may affect egglaying and behavior after mating.
Subcellular location: Secreted {ECO:0000269|PubMed:7711745}.
Interaction partners:
- Accessory gland-specific peptide 57Da
- Accessory gland-specific peptide 57Dc
- GEO13347p1
- Seminal fluid protein 24Bb
- Seminal fluid protein 96F
- FI11009p
- Testis-specific Plus3 domain b
- ACP24A4
Sequence:
MKITSALVLLFAGVAFAQSADPNTNENKNVIHINSPSAAK
Protein: Dot/Icm secretion system protein IcmQ (IcmQ protein) (O54635)
Organism: Legionella pneumophila
Interaction partners:
- IcmR protein
Sequence:
MKDQLSDEQKETILKALNDAIEKGPWDKSNFLRVIGKKLIAIRDRFLKRIGAASQAKLKAESHLANRIALRSGQQEIYVSLYSSDGSNLQSWEKIVGSLPRQMISRPIYADEEDIKAILKTKENKQNEAYVAIYISQSDILHLSADKAPVDKLGKPLLTLKDKSISLENISRFVHVSGVYRYSNGRLIKNA
Protein: Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) (60S ribosomal protein L10E) (P19945)
Organism: Rattus norvegicus (Rat)
Function: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P05388}. Cytoplasm {ECO:0000250|UniProtKB:P05388}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000250|UniProtKB:P05388}.
Interaction partners:
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL13
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein uL18
- FAU ubiquitin like and ribosomal protein S30 fusion like 2
- Large ribosomal subunit protein P1
- Small ribosomal subunit protein uS2
Sequence:
MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLIIQQVFDNGSIYSPEVLDITEQALHTRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFAAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD