wanglab/gogpt-training-data huggingface dataset:
Protein: Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI) (O70622)
Organism: Mus musculus (Mouse)
Function: Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (By similarity). Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity). Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O75298}; Multi-pass membrane protein {ECO:0000255}. Sarcoplasmic reticulum membrane {ECO:0000269|PubMed:19720795}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q6WN19}; Multi-pass membrane protein {ECO:0000255}. Cell membrane, sarcolemma {ECO:0000269|PubMed:19720795}; Multi-pass membrane protein {ECO:0000255}. Cell membrane, sarcolemma, T-tubule {ECO:0000269|PubMed:19720795}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:10672514}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10672514}. Note=Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes. {ECO:0000269|PubMed:10672514}.
Interaction partners:
- Atlastin-1
- Receptor expression-enhancing protein 1
- Spastin
- Receptor expression-enhancing protein 2
- Atlastin-2
- Atlastin-3
Sequence:
MGQVLPVFAHCKEAPSTASSTPDSTEGGNDDSDFRELHTAREFSEDEEEETTSQDWGTPRELTFSYIAFDGVVGSGGRRDSVVRRPRPQGRSVSEPRDPPQQSGLGDSLESIPSLSQSPEPGRRGDPDPVPPAERPLEELRLRLDQLGWVVRSAGSGEDSATSSSTPLENEEPDGLEASEAGEETNLELRLAQSLHLQLEVLTPQLSPSSGTPQAHTPSPQRSQDSNSGPDDEPLLNVVEEHWRLLEQEPITAQCLDSTDQSEFMLEPLLLVADLLYWKDTRTSGAVFTGLMASLLCLLHFSIVSVAAHLALLGLCATISLRVYRKVLQAVHRGDGTNPFQAYLDMDLTLTREQTERLSQQIASHVVSTATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLVILGVVALFTVPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIPGTGTLAPTASVSGSKAKAE
Protein: Kelch domain-containing protein 8B (Q8IXV7)
Organism: Homo sapiens (Human)
Function: Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19706467, ECO:0000269|PubMed:20107318}. Midbody {ECO:0000269|PubMed:19706467, ECO:0000269|PubMed:20107318}. Note=In mitotic cells, concentrates in the midbody of the cytoplasmic bridge linking daughter cells as they are about to separate during cytokinesis. {ECO:0000269|PubMed:19706467, ECO:0000269|PubMed:20107318}.
Interaction partners:
Sequence:
MSAGGGRAFAWQVFPPMPTCRVYGTVAHQDGHLLVLGGCGRAGLPLDTAETLDMASHTWLALAPLPTARAGAAAVVLGKQVLVVGGVDEVQSPVAAVEAFLMDEGRWERRATLPQAAMGVATVERDGMVYALGGMGPDTAPQAQVRVYEPRRDCWLSLPSMPTPCYGASTFLHGNKIYVLGGRQGKLPVTAFEAFDLEARTWTRHPSLPSRRAFAGCAMAEGSVFSLGGLQQPGPHNFYSRPHFVNTVEMFDLEHGSWTKLPRSLRMRDKRADFVVGSLGGHIVAIGGLGNQPCPLGSVESFSLARRRWEALPAMPTARCSCSSLQAGPRLFVIGGVAQGPSQAVEALCLRDGV
Protein: Uncharacterized protein (Q386R9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGCGGSKPNAVSRDVEEKALYLRGIKESIDKAEGNMLATLHALQALMRSYESTSYSFVELAHGTDGNTSLKAKTFESDMRTLKDSGIMPKLQKDLGQSVSSLGKDIRAKHDKANVVYREMTQANDAYCKLRERVNGIEKSYAKKNKPVSECPSYTKNCKERDVCLARYEGLKKVFLTLVEELRTLIRSYVTAGLTRYAFSTADYAQQLVNSLQKYKSE
Protein: Roundabout homolog 4 (Q8C310)
Organism: Mus musculus (Mouse)
Function: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Involved in the maintenance of endothelial barrier organization and function (By similarity).
Interaction partners:
- Slit homolog 3 protein
- Slit homolog 2 protein
- Slit homolog 1 protein
- Netrin receptor UNC5B
- Transcription factor SOX-18
- Paxillin
- Multimerin-2
- Claudin-5
- Endomucin
- Cadherin-5
Sequence:
MGSGGTGLLGTEWPLPLLLLFIMGGEALDSPPQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPDGTLLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAVVGESLVLECGPPWGYPKPSVSWWKDGKPLVLQPGRRTVSGDSLMVSRAEKNDSGTYMCMATNNAGQRESRAARVSIQESQDHKEHLELLAVRIQLENVTLLNPEPVKGPKPGPSVWLSWKVSGPAAPAESYTALFRTQRSPRDQGSPWTEVLLRGLQSAKLGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQGVTLRSGNGSVFVSWAPPPAESHNGVIRGYQVWSLGNASLPAANWTVVGEQTQLEIATRLPGSYCVQVAAVTGAGAGELSTPVCLLLEQAMEQSARDPRKHVPWTLEQLRATLRRPEVIASSAVLLWLLLLGITVCIYRRRKAGVHLGPGLYRYTSEDAILKHRMDHSDSPWLADTWRSTSGSRDLSSSSSLSSRLGLDPRDPLEGRRSLISWDPRSPGVPLLPDTSTFYGSLIAEQPSSPPVRPSPKTPAARRFPSKLAGTSSPWASSDSLCSRRGLCSPRMSLTPTEAWKAKKKQELHQANSSPLLRGSHPMEIWAWELGSRASKNLSQSPGPNSGSPGEAPRAVVSWRAVGPQLHRNSSELASRPLPPTPLSLRGASSHDPQSQCVEKLQAPSSDPLPAAPLSVLNSSRPSSPQASFLSCPSPSSSNLSSSSLSSLEEEEDQDSVLTPEEVALCLELSDGEETPTNSVSPMPRAPSPPTTYGYISIPTCSGLADMGRAGGGVGSEVGNLLYPPRPCPTPTPSEGSLANGWGSASEDNVPSARASLVSSSDGSFLADTHFARALAVAVDSFGLSLDPREADCVFTDASSPPSPRGDLSLTRSFSLPLWEWRPDWLEDAEISHTQRLGRGLPPWPPDSRASSQRSWLTGAVPKAGDSS
Protein: TNF alpha induced protein 6 (B0BN34)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MVFLLCLCVLLWEEAHGWGFKNGIFHNSIWLEQAAGVYHREARAGRYKLTYAEAKAVCEYEGGRLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPNAKECGGVFTDPKRIFKSPGFPNEYDDNQVCYWHIRLKYGQRIHLSFLDFDLEHDPGCLADYVEIYDSYDDVHGFVGRYCGDELPEDIISTGNVMTLKFLSDASVTAGGFQIKYVTVDPAPKSNQGKNTTMTGNKKFLAGRFSHL
Protein: Keratin-associated protein 19-2 (Q3LHN2)
Organism: Homo sapiens (Human)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Interaction partners:
- Keratin-associated protein 19-3
Sequence:
MCYGYGCGCGSFCRLGYGCGYEGCRYGCGHRGCGDGCCCPSCYRRYRFTGFY
Protein: Adhesion G protein-coupled receptor A2 (G-protein coupled receptor 124) (Tumor endothelial marker 5) (Q91ZV8)
Organism: Mus musculus (Mouse)
Function: Endothelial receptor which functions together with RECK to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B). Plays a key role in Wnt7-specific responses, such as endothelial cell sprouting and migration in the forebrain and neural tube, and establishment of the blood-brain barrier. Acts as a Wnt7-specific coactivator of canonical Wnt signaling: required to deliver RECK-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex (By similarity). ADGRA2-tethering function does not rely on its G-protein coupled receptor (GPCR) structure but instead on its combined capacity to interact with RECK extracellularly and recruit the Dishevelled scaffolding protein intracellularly (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:25558062, ECO:0000269|PubMed:28803732}; Multi-pass membrane protein {ECO:0000255}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q96PE1}. Note=Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact. {ECO:0000250|UniProtKB:Q96PE1}.
Interaction partners:
- Reversion-inducing cysteine-rich protein with Kazal motifs
- Catenin beta-1
- Frizzled-4
- Low-density lipoprotein receptor-related protein 6
- Norrin
- Protein Wnt-3a
- Segment polarity protein dishevelled homolog DVL-1
- Protein Wnt-7a
- Glycogen synthase kinase-3 beta
- Axin-1
Sequence:
MGAGGRRMPVPPARLLLLPLLPCLLLLAPGTRGAPGCPVPIRGCKCSGERPKGLSGGAHNPARRRVVCGGGDLPEPPDPGLLPNGTITLLLSNNKITGLRNGSFLGLSLLEKLDLRSNVISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIYSSLQPGVFDELPALKIVDFGTEFLTCDCRLRWLLPWARNHSLQLSERTLCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLPFQCSASYLGNDTRIHWYHNGAPMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQGNTSKKVEIVVLETSASYCPAERVTNNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLTCTAFQRREVGVSGAQPSSVGQDAPVEPEPLADQQLRFRCTTGRPNISLSSFHIKNSVALASIQLPPSLFSTLPAALAPPVPPDCTLQLLVFRNGRLFRSHGNNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGADPMAAWWNQDGPGGWSSEGCRLRYSQPNVSSLYCQHLGNVAVLMELNAFPREAGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFVGGVTLTNYQMVCQAVGITLHYSSLSSLLWMGVKARVLHKELSWRAPPLEEGEAAPPGPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILPITWIYFLCAGLHLRSHVAQNPKQGNRISLEPGEELRGSTRLRSSGVLLNDSGSLLATVSAGVGTPAPPEDGDGVYSPGVQLGALMTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPSASHVPARALPTATEDGSPVLGEGPASLKSSPSGSSGRAPPPPCKLTNLQVAQSQVCEASVAARGDGEPEPTGSRGSLAPRHHNNLHHGRRVHKSRAKGHRAGETGGKSRLKALRAGTSPGAPELLSSESGSLHNSPSDSYPGSSRNSPGDGLPLEGEPMLTPSEGSDTSAAPIAETGRPGQRRSASRDNLKGSGSALERESKRRSYPLNTTSLNGAPKGGKYEDASVTGAEAIAGGSMKTGLWKSETTV
Protein: Terminase, large subunit (DNA-packaging protein A) (Large terminase protein) (gpA) [Includes: Endonuclease (EC 3.1.21.4); Helicase (EC 3.6.4.12); ATPase (EC 3.6.4.-)] (P03708)
Organism: Escherichia phage lambda (Bacteriophage lambda)
Function: The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome from the concetamer to initiate and to end the packaging reaction. The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (binding to packaging sequence cos), and a large terminase subunit possessing endonucleolytic, ATPase and helicase activities (DNA maturation and packaging). The terminase binds cooperatively with the host factor IHFA/IHFB to the cos site at the junction of adjacent viral genomes. The endonuclease activity cleaves the viral DNA generating 5'overhangs of 12 bp in length. The helicase activity separates the cohesive ends generating the single-stranded 'sticky' ends of the mature genome. IHFA/IHFB is also necessary for the strand separation activity of the terminase. The terminase remains bound to the left end of the genome to be packaged, forming a stable DNA-terminase complex. In a reaction facilitated by the viral assembly catalyst gpFI, the DNA-terminase complex binds to the portal of the procapsid thereby activating the translocase activity of the terminase. The terminase packages the viral DNA into the procapsid until the next cos site on the concatemer reaches the complex (Probable). The downstream cos site is then cut generating the mature right end of the genome, the heterotrimer undocks from the DNA-filled head and remains bound to the left end of concatemer's next genome.
Subcellular location: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04144}. Note=The terminase lies at a unique vertex of the procapsid during viral DNA packaging. {ECO:0000255|HAMAP-Rule:MF_04144}.
Interaction partners:
Sequence:
MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKESAYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTLIWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFTNGRGFWCLGGKAAKNYREKSVDVAGYDELAAFDDDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVRGTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEHNACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFTTWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDRVAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYTRRNGAEMSISRICWDTGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNKNGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQVEKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAATNKKTLADYARALSGEDE
Protein: CTD nuclear envelope phosphatase 1 (I3L1D9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XQCLLGLRTFVAFAAKLWSFFIYLLRRQIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTAD
Protein: Zinc-finger homeodomain protein 10 (AtZHD10) (Homeobox protein 23) (AtHB-23) (Q9FIW9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription factor. Probably involved in establishing polarity during leaf development through the gibberellic acid (GA) signaling pathway.
Subcellular location: Nucleus {ECO:0000250}. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm. {ECO:0000250}.
Interaction partners:
- Zinc-finger homeodomain protein 13
- Zinc knuckle
Sequence:
MMDMTPTITTTTTPTPKSPEPESETPTRIQPAKPISFSNGIIKRHHHHHHPLLFTYKECLKNHAAALGGHALDGCGEFMPSPSSISSDPTSLKCAACGCHRNFHRRDPDNNNDSSQIPPPPSTAVEYQPHHRHHPPPPPPPPPPRSPNSASPPPISSSYMLLSLSGTNNNNNNLASFSDLNFSAGNNHHHHHQHTLHGSRKRFRTKFSQFQKEKMHEFAERVGWKMQKRDEDDVRDFCRQIGVDKSVLKVWMHNNKNTFNRRDIAGNEIRQIDNGGGNHTPILAGEINNHNNGHHGVGGGGELHQSVSSGGGGGGFDSDSGGANGGNVNGSSSS
Protein: C-sno protein (SnoN) (Q05951)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MESPQANFPLGLVSEQKRSGMQEDGSPPLKKLMTEMHVNSPVQVVINKLPTIKKENLDEYDETSVEADGESAKPNSSSVSEPLNLNPGLKHTLAQFHLSSQSSLGGPAAFSARYSQESMSPTVFLPLPSPQILSLPLLIPPDSSTELTQTVLEGESISCFKVGGEKRLCLPQVLNSVLRDFSLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGGFLPGKNTLAQLKETGSAFEVEHECLGKCQGLFAPQFYLAPDDPCIQCLECYGMFSPQTFVMHSHRSPDKRTCHWGFESAKWHCYLHINQKYLGTSEERELKHLLEEMKEKFSEKNQKRTRSKVDSQQSLELSQWYPVIKQEAEADPQPPSFFHPSYYLYMCDKVVAPNVSLASQYKDVTKTTGKASEVIKSSSGTSEKKLSSGKHKKPASYPELSLEEQEKIDLKTGLEQHKRLDPLVSAHSARGGRSERISSKSIRGSRCVEVGNDGRTLSPTLMKDISCEDDKGRIMEEVMKTYIKQQEKLNTILRRKQQLQMEVEMLNNSKAMKELSEEQQNLQKELESLQTEHAQRMEEFYFEQRDLEKKLDQMMKQKCTCDSSSEKDKEAEYAAQLAELRQRLDHAEADRQELQDELRQEREAREKLEMMIKELKLQILKSSKNGNGK
Protein: DNA repair protein RAD14 (P28519)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleotide excision repair. Binds specifically to damaged DNA. Required for the incision step.
Subcellular location: Nucleus.
Interaction partners:
- General transcription and DNA repair factor IIH helicase subunit XPD/RAD3
- DNA repair protein RAD10
- DNA repair protein RAD1
- DNA repair protein RAD4
- DNA repair protein RAD2
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2
- DNA repair protein RAD7
- DNA repair protein RAD16
- UV excision repair protein RAD23
- General transcription and DNA repair factor IIH subunit TFB1
Sequence:
MTPEQKAKLEANRKLAIERLRKRGILSSDQLNRIESRNEPLKTRPLAVTSGSNRDDNAAAAVHVPNHNGQPSALANTNTNTTSLYGSGVVDGSKRDASVLDKRPTDRIRPSIRKQDYIEYDFATMQNLNGGYINPKDKLPNSDFTDDQEFESEFGSKKQKTLQDWKKEQLERKMLYENAPPPEHISKAPKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRREKKYEKKIKEMRLKTRAQEYTNRLREKKHGKAHIHHFSDPVDGGIDEDGYQIQRRRCTDCGLETEEIDI
Protein: Fibroblast growth factor (FGF) (C4P6Q2)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MDPCSSLFSYVFMHLFVLCLQAQVTVQSPPNFTQHVREQSLVTDQLSRRLVRTYQLYSRTSGKHVQILDNKKINAMAEDGDVHAKLIVETDTFGSRVRIKGAATGFYICMNKKGKLIGKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFM
Protein: Meiotic recombination protein rec15 (Q09094)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required during the early stages of meiosis for meiotic recombination.
Subcellular location: Nucleus {ECO:0000269|PubMed:16252089, ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:31665745}. Chromosome {ECO:0000269|PubMed:31665745}. Note=Localizes to meiotic chromosomal axis sites and DNA double-strand break (DSB) hotspots. {ECO:0000269|PubMed:31665745}.
Interaction partners:
- Mei4-dependent protein 2
- Meiotic recombination protein rec7
- Linear element protein rec10
- Meiotic recombination protein rec24
- Meiotic recombination protein rec6
- Meiotic recombination protein rec12
- Meiotic recombination protein rec14
- Linear element protein rec25
- Linear element protein rec27
- Meiotic recombination protein rec11
Sequence:
MSYSVSAAQLWSRKLAMQAEDMQQHQKSQSNQIASCLAEMNTKQEVVNQTIGQLGRSISEVQQQNSQLVLQSLNQINMSMQQVALGIQDYASRINKLEQTMSDMNLKFEALQKEQNSNTKTLADCTSQMTIITKKLDAELKKRYMTTKQTRTVQNQTMPRSNTTTKKRVLAIDFLADDDY
Protein: Carnitine O-palmitoyltransferase 1, muscle isoform (Carnitine O-palmitoyltransferase I, muscle isoform) (Carnitine palmitoyltransferase 1B) (A2RRE8)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004374}.
Interaction partners:
Sequence:
MELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSRHVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAPPTRLQWDIPKQAVIKSSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQVPKAYS
Protein: 5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (EC 2.7.11.26) (EC 2.7.11.31) (Acetyl-CoA carboxylase kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (Tau-protein kinase PRKAA1) (W5PHS8)
Organism: Ovis aries (Sheep)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein kinase AMP-activated non-catalytic subunit beta 1.
- 5'-AMP-activated protein kinase subunit beta-1
- 5'-AMP-activated protein kinase subunit gamma-1
- CBS domain-containing protein
- Protein kinase AMP-activated non-catalytic subunit gamma 3
- Serine/threonine-protein kinase STK11
- Raptor N-terminal CASPase-like domain-containing protein
- Serine/threonine-protein kinase mTOR
- Tuberin
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
Sequence:
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVRTGSMKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRACQRNDSDAEAQGKSSEASLTSSVTSLDSSPVELTPRPGSHTIEFFEMCANLIKILAQ
Protein: FCS-Like Zinc finger 7 (F4JW68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:29945970}. Nucleus {ECO:0000269|PubMed:29945970}.
Interaction partners:
- Putative defensin-like protein 101
- Putative defensin-like protein 62
- Defensin-like protein 90
- FCS-Like Zinc finger 16
- Equilibrative nucleotide transporter 5
- Equilibrative nucleotide transporter 4
- Equilibrative nucleotide transporter 6
- Equilibrative nucleotide transporter 3
Sequence:
MLLGNRPRPQMQRTASITRITIEVDGDQTAGQDSDVSMTVVDGGENYAQRFLSPVNHQRNERKYGGRSSPSSFLVNCGFCKRGLAPGRDIYMYKGDAAFCSIECREQQMEHDEGKTRNRVVLSPSK
Protein: APC regulator of WNT signaling pathway (E9PFT7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQI
Protein: Similar to FI genes of P2, phiCTX, and PS17: tail sheath (Q9S574)
Organism: Pseudomonas aeruginosa
Interaction partners:
Sequence:
MSFFHGVTVTNVDIGARTIALPASSVIGLCDVFTPGAQASAKPNVPVLLTSKKDAAAAFGIGSSIYLACEAIYNRAQAVIVAVGVETAETPEAQASAVIGGISAAGERTGLQALLDGKSRFNAQPRLLVAPGHSAQQAVATAMDGLAEKLRAIAILDGPNSTDEAAVAYAKNFGSKRLFMVDPGVQVWDSATNAARNAPASAYAAGLFAWTDAEYGFWSSPSNKEIKGVTGTSRPVEFLDGDETCRANLLNNANIATIIRDDGYRLWGNRTLSSDSKWAFVTRVRTMDLVMDAILAGHKWAVDRGITKTYVKDVTEGLRAFMRDLKNQGAVINFEVYADPDLNSASQLAQGKVYWNIRFTDVPPAENPNFRVEVTDQWLTEVLDVA
Protein: Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 90 kDa subunit homolog) (eIF3 p90) (Translation initiation factor eIF3, p90 subunit homolog) (G0RXS6)
Organism: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_03001, ECO:0000256|PIRNR:PIRNR036424}.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit F
- Eukaryotic translation initiation factor 3 subunit D
- Eukaryotic translation initiation factor 3 subunit J
- Eukaryotic translation initiation factor 3 subunit H
- Eukaryotic translation initiation factor 3 subunit A
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit M
- Eukaryotic translation initiation factor 3 subunit K
- Eukaryotic translation initiation factor 3 subunit E
Sequence:
MAPSFDHLREEDLDEEDIDMDEVDISDLREKYEVQLEQGYDTFVVIDGLPAVSEEQKPKLIKFLLKKLNTVGKTREDMIYMPMGDDGMSLRFAFVEYSSPAEASAAVRQLDYVPLDKKHTLRVNKLTDIDRYGREGRISEEFVPPKIEPFQEKEHLRWFMADPADRGRDQFVMYRGDTVGVFWNNEKDQPENIVDRQHWTETFVQWSPLGTYLTSVHAQGVQLWGGASWSRLRRFPHPFVNLVAFSPGEKYLVTWSNRPIQIPDSGHPVLTLDDDGKNYIIWDIETARPLRSFAQQDIHPEEHGPKKGPPKFPWPVFKWSADDKYVARLNQGTSISIYELPKMNLLDKQAVKIEGVMDFEWAPATVQREGVKTYEQLFCFWTPEIGNNPARVGLMSIPSKQIVRTLNLFSVSDVKMHWQSEGTYLCVKVDRHSKSKKSQATTLEIFRVKEKGVPVEVVDTIKDTVINFAWEPKGDRFVIITTPEPVGATAVPPKTSVSFFCPELKKGNQVGSFKHLRTLEKKNHNAIYWSPKGRFVVIATVHNTQSSDLEFWDLDFDGEKPENEKDLAACLQLMGTGDHYGITDVEWDPSGRYVATWASAWKHTMENGYHLYDFKGELLREEHIEKFKQWQWRPRPPTLLTKEEQKQIRKNLREYSRIFEQEDAERISSADVAVVEARRRLLNEWYAWREAIEKEVAEERAALGLPADPAAELLKRKIAEVAPDAQEQVIEEIMEEVLEETEEIVN
Protein: CYtochrome P450 family (Q9N5I1)
Organism: Caenorhabditis elegans
Interaction partners:
- CYtochrome P450 family
- Fatty acid synthase
Sequence:
MFFVLFIAACLSWLIVRQYQKVSRHPPGPISFPLIGNLPQICYYLWSTGGIVSALDLLRKKYGNIFTLWVGPVPYVSIADFETSHEVFVKNGGKYADKLHAPIMRDIRKDKGIAFTNGDHWQEMRRFSLQTFRNMGVGKDIMETRILEELDARCSDIDKSAKNGVTVAQASEFFDLTVGSVINSILVGKRFEEDTKHVFLRIKNTIDESFKLITPFNTTVPVWILKTFFKDRYDKMADAQEIAKNFVAAEALKRIEDIKSGKYVIDENNLQDYTDAFLLKMQKEGENLDFNTETLKTMLVDLWLTGQETTTTTLTSGFNQLLLHPEVMVKAREELMNVTENGSRSLSLTDRSSTPYLNAMIGEIQRHASILNLSFWKVNKEFTYIGGHPVDAGALVTAQLSALHVNETYFTNPQVFEPERYSQDEKLLQKIIPFGVGKRSCLGESLAKAELYLIFGNLLLRYKFEPHGKLSATDLMPYSAGRRPFKLEMKFVKI