wanglab/gogpt-training-data huggingface dataset:
Protein: Signal recognition particle sec65 subunit (O94407)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Signal recognition particle subunit SRP54
- Signal recognition particle subunit srp14
- Signal recognition particle subunit srp68
- Uncharacterized protein C17H9.07
- Signal recognition particle subunit srp72
- Signal recognition particle receptor subunit alpha homolog
- Signal recognition particle receptor subunit beta
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein uL29
Sequence:
MISHLLPTTSLTIHMPSIILYPIYFDKSRPRRFRCVPKDKAILNPLAKNIADVVRDLGYKCKLEPLKTHPADWVNPGRVEMVLPEKIQKKYVINEIAKVLLLRPTVKTDPLSLPIQNVPARLPENPPAYPKGVLGNTILPLHSPALSGGGISENMFQEMMQEMQKQPGLAGGMNPMAALAGMGGPAPPMPTPQASSSQRKQKSIEPEYDLDLE
Protein: Transcription factor E2F8 (E2F-8) (F1QZ88)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as e2f1. Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC-3' and mediating repression of G1/S-regulated genes (By similarity). Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator and promoting expression of vegfa.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription factor E2F7
Sequence:
MSSTLSEGQTLIKKSLSPSKATSTNNKGHVFVEPQTPLKNSNKASTSEAALPETLKIMGPLTTPTKVLDAPSSDPWTPTSNLKMLISAASPEIRNREKERAVDSSESENSQETEQGEEVEKLHISRKDKSLGLLCYKFLARYPNYPNPALNNGISLDDVAAELHVERRRIYDIMNVLESLNMVSRLAKNRYTWHGRVKLAQTLAVLKRAGKENRYEQLMQQIRQRSQEREEREFDLDGEEKENEEMSSFEVDGDSGLADLPGADSKAASANSRKDKSLRVMSQKFVMLFLVSSPPVVSLDVAAKILIGEDHVVDQDKNKFKTKIRRLYDIANVLSSLELIKKVHVTEDKGRKPAFKWTGPEDIPSPKDLEISTTSSAPKPLESRSSVENCAKNLFSSPGTKRGFTRHHSLVKLVKSIQDDRRKINSAPSSPIKMTGDSADSDFYTTKMAHLAAICKKHLDEQSADGRPNNAVTDSSQSSKQPESTSASNHGPPGMQIPVLPAGAISYLPTKCSPIIPLLIPQHQTGGPYAVYMHPTSLRPQPTSLAVRSMTFESPVGANAKTSPATLTSNNQTNQSSSYGKEQTSPVNLKRASGEKSSVGSPSKMQRTEPKSVSPKLCEILQARLKARRGALTSNRPSARALHLEFSKPSESQPTVQTGTASLEHSLETFLEKEEKSQTSDNEAGLTPVRQPHSQPQKLSAPFQDMVLPSGPIHTETLIPAGYLIPISQQSIVNFREPQCSNESSKASTPTYNIYHTPTAGSRPAFPQEVTPTRLPLHRIPPISPFPSHGHRLHSPSPAILNFTLQNLGLIPGSVTPNPHTPEQSSSLQSPHPGLPHQGMIFVKPMSPARALQQTSIHGQPVTLISIPQALVTTPKGGQAFQQSFFHTPVSFPTVNTTAPKKIYIPQRKLDVSPEEI
Protein: Zn(2)-C6 fungal-type domain-containing protein (G5EB63)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MASPAAPKHKPFKQACDNCRRRKIKCSRELPCDKCQRLLLSCSYSDVLRRKGPKFRTLYPLAPIHPLVARDRQILQYDPPRFSAEREWYAEPTSYPVGGSPTSPPFMEEPQYLPPEHPDSFSRLPPPELVSSPDSLNSLSDSPTAVLFRSPRILTAPVLLAHVNVYLKYMFPIMPVVRREELQQDCHHPERLTPQRYAFLASLCAATHIQLKLDGATPVADPSHFQAGENSSMSGEELLAEAVRARKDCDPIEDMNVESLLTSFFLFASYGNLDRQDHAWFYLCQATSMVFALGLHRESTYAELNTEEAEQKRRVFWLLFITERGYALQQAKPVMLRNSIHKPQVLCSDDPILAYGFINLIGVFESLSVNLYDWVSAGGSVSGGGNNRDGSSEMPPTSAIQATLSKPISLEGVSEIQKVDILITQQWLQAMMWKLSMTRASQPGSRNETVLPFHLPVMVGKAVMSVIAEASQGAVDAHGIGMEQKLFDLGTSIADVSRSLSTKAANSLAESTVDPRELLWGILSTLSRIRGSQSYLFPSLLERCKGTLGFDSPTPLSISDFHQINPPLLNSASSSSIASETLDISGPWPAADDNTMDSSTGSRTTNSCAWEITSGDTNDQNQTSDQPPSLSGSSSVPLSVSRMHSSTSMAAELSFQAGRLLT
Protein: Calcium channel, voltage-dependent, alpha 2/delta subunit 1a (Voltage-dependent calcium channel subunit alpha-2/delta-1a precursor) (Q5TZ68)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Voltage-dependent calcium channel gamma-1 subunit
- Voltage-dependent calcium channel gamma-1 subunit
- Calcium channel, voltage-dependent, beta 2a.
- Voltage-dependent L-type calcium channel subunit beta-2
- Voltage-dependent L-type calcium channel subunit beta-1
- Voltage-dependent L-type calcium channel subunit beta-4
- Calcium channel, voltage-dependent, beta 3a.
- Voltage-dependent calcium channel beta 2a subunit.
- Voltage-dependent L-type calcium channel subunit alpha
- Voltage-dependent L-type calcium channel subunit alpha
Sequence:
MSVRRMMDALRLSTALLLLLSLCSFGSAIQFPDSFLTRKWAEKMQEDLVQLIDSESGIKELKKIFNNFQRHYTVRQNNPRQLVEKASHEIEEFLANRSKALEALATAAENLQKEHQWKEDLDVNETIYYNAKDKSDNQTEPRKNRLILDFTEDPAFKRPVSYNTTAVHIPTDIYEGSTIILNELNWTAALDDVFRKNKEDDPSLHWQVFGSATGLARYFPASPWVDSKNKIDLYDVRRRPWYIQGAASPKDMLILVDASGSVSGLTLKLIRTSVSEMLETLSDDDYVNIVSFNNSAKSVACFENLVQANVRNKKTLKEAVQKITANGTTDYKIGFKEAFNQLASMNVSRANCNKIIMLFTDGGEDKASEIFDEYNSDKRVRIFTFSVGQHNYDKAPIQYMACHNKGYYYEIPSIGAIRINTQEYLDVLGRPMVKADKKAKNVQWTNVYVDALELGLVVTGTLPVFNKTRTSKEKPKNLGPSQMILGVMAIDVSLDDIKRLTPHYTLGPNGYYFAIDPNGYVLLHPNLQPKDLKSQEPVTLDFLDAEMEDEVKVDIRRSMIDGERSQIRFHTLMKSQDERYIDKGFRTYTWSPVTDADYSLALVLPDYSMSYIKATIGDTITQAKFSESLQVDKFEEYGYTLIAPRDYCEDLKAQNENMTQFLIDFNEYIDVKTPNDPQCNMDLMNRLLLDAGITAELVKHWNKNQLSDRIKAKFVATDGGVTRVYPASAGSEWTGQAETYESSFYKRSLDNDLYVFTPLPFTGNKTEESVLVSRAMDLRIDEFWLKPAVVGVKLDVQSWMESFMNTTITPKCEGEICGCRRNDEYLDCVLLDDGGFLVMANQDKYIDQIGEFFGMIDPSLMRNLMNVSLFSVNITYDYQALCEPTRESKAAAGLRSVYVPTIADILNIGWWASAAAWSIMQQLFVSITFPNFLEAVDISDESETPSKESCIKEQTQYFFDSNDTTFKGTVDCQNCSRQFIAEKLMKTNLVLIVADTEMCSQMSPGPDPCLISQNPRYRKGPMECFDNNVNENNEPCGGATSLTPSLVSMGILQLLLLLWLLIGREHCLS
Protein: Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9) (Q13242)
Organism: Homo sapiens (Human)
Function: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
Subcellular location: Nucleus {ECO:0000269|PubMed:10196175, ECO:0000269|PubMed:11694584, ECO:0000269|PubMed:12024014, ECO:0000269|PubMed:12604611}. Note=Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.
Interaction partners:
- Transformer-2 protein homolog beta
- Serine/arginine-rich splicing factor 7
- Serine/arginine-rich splicing factor 1
- Serine/arginine-rich splicing factor 2
- SRSF protein kinase 1
- Serine/arginine-rich splicing factor 3
- Splicing factor U2AF 65 kDa subunit
- Serine/arginine-rich splicing factor 6
- Serine/arginine-rich splicing factor 11
- Serine/arginine-rich splicing factor 10
Sequence:
MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY
Protein: Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor) (O35054)
Organism: Mus musculus (Mouse)
Function: Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Subcellular location: Cell junction, tight junction {ECO:0000269|PubMed:20921420, ECO:0000269|PubMed:25831548, ECO:0000269|PubMed:9892664}. Cell membrane {ECO:0000269|PubMed:20921420, ECO:0000269|PubMed:9892664}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Tight junction protein 1
- Occludin
- Tight junction protein ZO-3
- Junctional adhesion molecule A
- Claudin-8
- Tight junction protein 2
- Claudin-7
- Claudin-1
- Ephrin type-A receptor 2
- Claudin-23
Sequence:
MASMGLQVLGISLAVLGWLGIILSCALPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKIMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPMVASGQKREMGASLYVGWAASGLLLLGGGLLCCSCPPRSNDKPYSAKYSAARSVPASNYV
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (Q90ZG0)
Organism: Gallus gallus (Chicken)
Interaction partners:
- TGF-beta receptor type-1
- Serine/threonine-protein kinase TOR
- Eukaryotic translation initiation factor 4E
- Activin receptor type-1
- Calmodulin
- Ribosomal protein S6 kinase
- Regulatory associated protein of MTOR complex 1.
- Protein phospatase 3 regulatory subunit B alpha isoform type 1
- Eukaryotic translation initiation factor 4E binding protein 1.
- Calmodulin, striated muscle
Sequence:
MGVHVETIAPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFVMGKQEVIRGWEEGVAQMSVGQRAKMTISPDYAYGSTGHPGIIPPNATLIFDVELMKLE
Protein: PAR-1 kinase N3 (Q9V8V7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEATTTTTPDLNRGDATRKSVRLYAARKGAAPAPPKLSVAPSSNQNSNHSSNNNNSSSNLPETEKEMELRQTHLANKDLDGATEDDSIVELRRRDAQATPLPRIAVSALPTLQPHPTPKERQKPPMPRLLSTEDDAGVSFALGSIEKHIHNVEESFKQQQQNQQSQSSMDVMKLEIKRKQSKRYGETENLLRPGISDMSSENDFQYLGGRRAGELDDSNELMLSEFQRGSDGRNSIGAYSKNSAAAANGANAVKAKLARTASDTKNNDTVLAMRATFKQKQHLQDEKQPAVWRPAGTGPTPAARSSSSTTSTSGSASRGGSSSSVVDGVAPSKLTATTISASKRREENLRQFEALLAQKSSHRHGASGASGTGSNAASSKRRSDRPIVAPIPPYNSSRAEHVTSSTRHSVDPRSHSGHESRSGTASTHPPVGHHPTSRVPSVVANRSNVYSNNAAQ
Protein: At2g43780/F18O19.11 (Cytochrome oxidase assembly protein) (O22825)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAGFPGFSYLGPKGKNTVVAGGLTAFVFGVYFYTMRAVGGTDELQVAIDKFEGQKQVDTDTKVPSKV
Protein: Hydrogenase 2 maturation protease (EC 3.4.23.-) (P37182)
Organism: Escherichia coli (strain K12)
Function: Protease involved in the C-terminal processing of HybC, the large subunit of hydrogenase 2. Specifically cleaves off a 15 amino acid peptide from the C-terminus of the precursor of HybC.
Interaction partners:
- Hydrogenase-2 large chain
- Hydrogenase maturation factor HybG
- Hydrogenase-2 operon protein HybE
- Probable Ni/Fe-hydrogenase 2 b-type cytochrome subunit
- Hydrogenase-2 small chain
- Hydrogenase maturation factor HybF
- Hydrogenase-1 large chain
- Hydrogenase-2 operon protein HybA
- Carbamoyltransferase HypF
- Hydrogenase 3 maturation protease
Sequence:
MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTAGMELLGDMANRDHLIIADAIVSKKNAPGTMMILRDEEVPALFTNKISPHQLGLADVLSALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPREAIHD
Protein: Solute carrier family 35 member B1 homolog (Protein medial glomeruli) (Q9VDD7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable sugar transporter.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- LD10780p
- UDP-sugar transporter UST74c
- IP10585p
- UDP-galactose transporter senju
Sequence:
MNLPERSRFVIYAVGIFVCYFLYGIVQEKLTRGRYGEEVQTDGSVGERFTYALALVWVQCLCNYVFAKVLLTIRPQKEDTTNAGSYVACSLTYLLAMVSTNMAMRWVPYPTAVVGKSAKPIPVMILGVLIGRKSYSWTRYACVLTIVLGVILFMYKEGKVSNLPAETTLLGEVLLFLSLSMDGLTGAVQERIRAASAPSGQQMMRAMNFWSTLMLGVAMVFTGEAKEFMYFTIRHPEAWTHLSLIAVCGVLGQFFIFLMVASFGPLACSVVTTTRKFFTVLCSVLLFGNVLIARQWLGAVLVFAALFVDMLYGKKAPLATAKKPPVEGKLSEEKKLNS
Protein: Heat shock protein 70 homolog lhs1 (EC 3.6.1.-) (Q10061)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Chaperone required for protein translocation and folding in the endoplasmic reticulum.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Endoplasmic reticulum chaperone BiP
- DnaJ-related protein spj1
- UBA domain-containing protein 7
- DnaJ homolog 1
- GrpE protein homolog
- Putative protein disulfide-isomerase C1F5.02
- Elongation factor 3
- mRNA export factor elf1
- Protein psi1
- DnaJ protein homolog xdj1
Sequence:
MKRSVLTIILFFSCQFWHAFASSVLAIDYGTEWTKAALIKPGIPLEIVLTKDTRRKEQSAVAFKGNERIFGVDASNLATRFPAHSIRNVKELLDTAGLESVLVQKYQSSYPAIQLVENEETTSGISFVISDEENYSLEEIIAMTMEHYISLAEEMAHEKITDLVLTVPPHFNELQRSILLEAARILNKHVLALIDDNVAVAIEYSLSRSFSTDPTYNIIYDSGSGSTSATVISFDTVEGSSLGKKQNITRIRALASGFTLKLSGNEINRKLIGFMKNSFYQKHGIDLSHNHRALARLEKEALRVKHILSANSEAIASIEELADGIDFRLKITRSVLESLCKDMEDAAVEPINKALKKANLTFSEINSIILFGGASRIPFIQSTLADYVSSDKISKNVNADEASVKGAAFYGASLTKSFRVKPLIVQDIINYPYLLSLGTSEYIVALPDSTPYGMQHNVTIHNVSTIGKHPSFPLSNNGELIGEFTLSNITDVEKVCACSNKNIQISFSSDRTKGILVPLSAIMTCEHGELSSKHKLGDRVKSLFGSHDESGLRNNESYPIGFTYKKYGEMSDNALRLASAKLERRLQIDKSKAAHDNALNELETLLYRAQAMVDDDEFLEFANPEETKILKNDSVESYDWLIEYGSQSPTSEVTDRYKKLDDTLKSISFRFDQAKQFNTSLENFKNALERAESLLTNFDVPDYPLNVYDEKDVKRVNSLRGTSYKKLGNQYYNDTQWLKDNLDSHLSHTLSEDPLIKVEELEEKAKRLQELTYEYLRRSLQQPKLKAKKGASSSSTAESKVEDETFTNDIEPTTALNSTSTQETEKSRASVTQRPSSLQQEIDDSDEL
Protein: UDP-rhamnose/UDP-galactose transporter 2 (UDP-Rha/UDP-Gal transporter 2) (Q9LPU2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Nucleotide-sugar transporter that transports UDP-rhamnose or UDP-galactose and UMP in a strict counter-exchange mode.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:25053812}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- DNAJ heat shock N-terminal domain-containing protein
- Probable galacturonosyltransferase-like 5
- GDP-fucose transporter 1
- Transmembrane E3 ubiquitin-protein ligase FLY1
- ER membrane protein complex subunit 3
- Pmr5/Cas1p GDSL/SGNH-like acyl-esterase family protein
- Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2
- Peroxidase 36
- Probable sugar phosphate/phosphate translocator At5g25400
- Probable sugar phosphate/phosphate translocator At4g32390
Sequence:
MEKAENEKKPSAVSDVGAWAMNVTSSVGIIMANKQLMSSSGFGFSFATTLTGFHFALTALVGMVSNATGLSASKHVPLWELLWFSLVANISIAAMNFSLMLNSVGFYQISKLSMIPVVCVMEWVLHSKHYSREVKASVMVVVVGVGICTVTDVKVNAKGFICACTAVFSTSLQQISIGSLQKKYSIGSFELLSKTAPIQAISLLIFGPFVDYFLSGRFISTYKMTYSAMLCILLSCALAVFCNISQYLCIGRFSATSFQVLGHMKTVCVLTLGWLIFDSEMTFKNIAGMVLAVVGMVIYSWAVELEKQRKSKVIPHGKHSMTEDEIKLLKEGIEHMDLKDMELGNNKA
Protein: Actin-interacting protein 1 (AIP1) (Uncoordinated protein 78) (Q11176)
Organism: Caenorhabditis elegans
Function: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Regulator of actin organization in myofibrils.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Actin-depolymerizing factor 2, isoform c
- Actin
- Profilin-3
- Tropomodulin
- Profilin-2
- F-actin-capping protein subunit beta
- Profilin-1
- Protein unc-87
- Gelsolin-like protein 1
- Alpha-actinin, sarcomeric
Sequence:
MSEFSQTALFPSLPRTARGTAVVLGNTPAGDKIQYCNGTSVYTVPVGSLTDTEIYTEHSHQTTVAKTSPSGYYCASGDVHGNVRIWDTTQTTHILKTTIPVFSGPVKDISWDSESKRIAAVGEGRERFGHVFLFDTGTSNGNLTGQARAMNSVDFKPSRPFRIISGSDDNTVAIFEGPPFKFKSTFGEHTKFVHSVRYNPDGSLFASTGGDGTIVLYNGVDGTKTGVFEDDSLKNVAHSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKTIPVGTRIEDQQLGIIWTKQALVSISANGFINFVNPELGSIDQVRYGHNKAITALSSSADGKTLFSADAEGHINSWDISTGISNRVFPDVHATMITGIKTTSKGDLFTVSWDDHLKVVPAGGSGVDSSKAVANKLSSQPLGLAVSADGDIAVAACYKHIAIYSHGKLTEVPISYNSSCVALSNDKQFVAVGGQDSKVHVYKLSGASVSEVKTIVHPAEITSVAFSNNGAFLVATDQSRKVIPYSVANNFELAHTNSWTFHTAKVACVSWSPDNVRLATGSLDNSVIVWNMNKPSDHPIIIKGAHAMSSVNSVIWLNETTIVSAGQDSNIKFWNVPF
Protein: Sal-like protein 1a isoform X1 (Spalt-like transcription factor 1a) (A0A1D5NSE4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNDTTNNTDQAELTDLLEQNILDKEEAMDTEMSGVSAPHNDGNGRMAGSSPLSGVGTGHGTLGSTGSNLGSSVISASLPQLGNLTELGNFSMINSNVIIENLQSTKVAVAQFSQETRATGGQRVAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLASQSPELQAPPSSSPVTLGSGTSPLTTLSSHLSQQLAAAAGLAQSIASQSASISSLKQMANVAQLPQSNSSVGESSQSLAAPGPAPVNAQPLEKRPGNAGSLHPPLGNPSLAKSSTPAFAMGNLLNPVANTLLPQPPPGNPIFSSALPSVGSTVEDLNSLAALAQQRKGKPPNVSSFEPKSSSEDTFFKHKCRFCGKVFGSDSALQIHLRSHTGERPYKCNICGNRFSTRGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPTSTGIPYGMSMPPEKPVTSWLDSKPVLSTLTSSVGMLLPPTIPSLPPFIKKEENNSLAISSPSHSAKSDSGPADTPMKNTDSVLEEGESTTLPTSNGKAEENNQSSNLLSNMSSAVEGTIEYTTSNSPPMATNPLMPLMSEQFKAKFPFGGLLDPLQGSETSKLQQLVENIDRKVADPNECVICHRILSCQSALKMHYRTHTGERPFKCKVCGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPDNYPESMGSDAGSFDERNIDDLDNFSDDNMEGIEDGPDSSIPDTPKSVDASQDSLCSSPTLHESFGMDERIQEKSANHGAGEEVQYDQGKSVENGLVEGDRFTNDSSSLGGDIESQSAGSPAVSESTSSMQAPSPSNGIFQQQKSPSMEDRQQRALSLEHISASLMHSNSASPGALDLTSVNSSKDPISMLFPFRERGTLKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPNTSLASSLASSPTPSLLSVGPLSSMMKTEVNGFLHGLQPEVKDLPPALVTSSASTSPVLSAAPPRRTPKQHFCTTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSAPARRGRRLSVDGPMAFLGTNPVKFPELFQKDLSSRAGNGDPTSFWNQYAAAFSNGLAMKTNEISVIQNGGLPPPLSGSVGNGGSSPIGGLTGSMEKLHNSEPNPALAGLEKMANTENGTHFRFTRFMEDKEIVTN
Protein: Dimethyl sulfoxide reductase DmsA (DMSO reductase) (DMSOR) (Me2SO reductase) (EC 1.8.5.3) (P18775)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS). DMSO reductase serves as the terminal reductase under anaerobic conditions, with DMSO being the terminal electron acceptor. Terminal reductase during anaerobic growth on various sulfoxides and N-oxide compounds. Allows E.coli to grow anaerobically on DMSO as respiratory oxidant.
Subcellular location: Cell membrane {ECO:0000269|PubMed:2170332, ECO:0000269|PubMed:3280546}; Peripheral membrane protein {ECO:0000269|PubMed:2170332, ECO:0000269|PubMed:3280546}; Cytoplasmic side {ECO:0000269|PubMed:2170332, ECO:0000269|PubMed:3280546}.
Interaction partners:
- Anaerobic dimethyl sulfoxide reductase chain B
- Anaerobic dimethyl sulfoxide reductase chain C
- Tat proofreading chaperone DmsD
- Anaerobic dimethyl sulfoxide reductase chain YnfH
- Probable anaerobic dimethyl sulfoxide reductase chain YnfG
- Chaperone protein TorD
- Probable Ni/Fe-hydrogenase 2 b-type cytochrome subunit
- Cytochrome c-type protein TorC
- Protein-methionine-sulfoxide reductase catalytic subunit MsrP
- Hydrogenase-2 operon protein HybA
Sequence:
MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAHAVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVRACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGNESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYGGWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTDTGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKNGHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHANGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTDAIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCELIVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTIYEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDPQGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGFESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGIHNGDKVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDKGGCINVLTTQRPSPLAKGNPSHTNLVQVEKV
Protein: Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) (H7C419)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU369008}.
Interaction partners:
Sequence:
XKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCCCLSLLFPHFLLFPVWRERTLRQQMHQRALGLSQWTVTAAGASSEQPGGPAVGSVHLTVSCAC
Protein: Quick-to-court, isoform G (Q59DZ9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSLQLNGGSDISSSGTSSSSSNNKESSPRTTRTPRTPQTPQTPQTPASGVAASVAETPHSCIRQGNCVKANQVKLSTLHESKISPRTPPVTPDSPSTYLDDDIDSMYSFATTTSGRSTMSCEHPYVARNGTTFSGRKMKYVVHCSNYAGQVGPDYLTPTQRAQRQIRRLKELLCIARQDLEQKDTELLRLTREVVELRLFKASLSSPEERSASSDAVTVREAELKTSQDVSPIVDMVDEGNAKGSPRHLSRQQQQQANHSLQAMQMSAEMQSSYADSGHFEDLTMSSVHSKDSQTQSEACGTATPDGEADVGCGAGGDSASNLENYELQRQELISMYEHRIEELIRSQDSATSDLKRSHNDKVEALLQKLAECNTRYSDMVPDYEQAKQRIRELEKQLEDLQRKLIEHEEKQNKMYLHMYQQGQEAERISRADQALDLAQRQPESKVSINELLHQLQSTQDELENIRTIYRRLLEAQKNRTHVDPEVTLQFLKSAIFYFLTDKENSQGHLQAIESILEFTDAEKQKISAANRTPK
Protein: Trefoil factor 3 (Intestinal trefoil factor) (hITF) (Polypeptide P1.B) (hP1.B) (Q07654)
Organism: Homo sapiens (Human)
Function: Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:8454642}. Cytoplasm {ECO:0000269|PubMed:10824705, ECO:0000269|PubMed:8454642}.
Interaction partners:
- IgGFc-binding protein
- Zinc finger protein 185
- Mucin-2
- Mucin-5AC
- Anterior gradient protein 2 homolog
- Trefoil factor 1
- C-X-C chemokine receptor type 4
- Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2
- Hepatitis A virus cellular receptor 1
- Hepatocyte nuclear factor 3-alpha
Sequence:
MAARALCMLGLVLALLSSSSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAECTF
Protein: LD11831p (Q95RU3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MIVQQQQQQQLSNEGEPKTLPGATASNSDEGCNVTGGGLSPYSSDNEDNSLSPRQRKMKVTRCASSDSALGLDVDDGGMDVPLPPQRRMTLTVTDLPLRPALLPLAEPTALPDSPLTSPTGGGNPSVGVPTKVLLEERVVAAPGSRRESTQSSYSELGVSGLPLGVRYVRTPSVVVSDYSDDITACGISMEEMEYFRLQRARGQRRCSLEAGHHSHSGGHGAHGHGGSGAAGMSPGCGKDDGQSDVSAASSCSNLYYCGSTISALDGGECIVNGVRVALARKSSTQSSSLSDEEEEEEDDDEDRDEQDRDEDDRDAEEMLQEDYERGDRERERERQISELMAATQLGDRQRDRSKKVGARDDVTNQGNLKLD
Protein: Vacuole membrane protein KMS1 (Protein KILLING ME SLOWLY 1) (Q5XF36)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the early secretory pathway. Required for the correct export of secretory products from the endoplasmic reticulum (ER) and involved in the maintenance of ER integrity.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21294794}; Multi-pass membrane protein {ECO:0000303|PubMed:21294794}.
Interaction partners:
- SUN domain-containing protein 1
- UDP-N-acetylglucosamine diphosphorylase 2
- Hypthetical protein
Sequence:
MGSAGVASSSSDVAISALREKHEKEVENLTLTTQPLNTLKLFVEATIQYIKRSISYLLAHGGWFILITTLLVVSGGLLVTVDGPHGKHVEEVLEYVRYGLWWIALGVASSIGLGSGLHTFVLYLGPHIALFTLKATLCGRVDLKSAPYDTIQLKRVPSWLDKSCSEFGPPLMISAAGSRVPLTSILPQVQLEAILWGIGTALGELPPYFISRAASISGSTVDGMEELDGSSTEDSGFMATHLNRVKRWLLTHSQHLNFFTVLVLASVPNPLFDLAGIMCGQFGIPFWEFFLATLIGKAIIKTHIQTIFIICVCNNQLLDWMENELIWILSHVPGLASMLPGLTAKLHAMKEKYIDAPSPVPSHIKVKKWDFSFASIWNGIVWLMLLNFFVKIVTATAQRHLKKKQEKEMATLTHSD
Protein: Exosome-associated protein 4 (Q8IEW0)
Organism: Trypanosoma brucei
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MERSHGRRSPDEVRYPHIVLNVLGQSYSSACIEVGSTRVVCAVHHPQQLIDEYRGSRGRVACTVRRSSRAQKHELAFRADVTPEKDLALALEGVVEQAVVLEKIPQLLVEVVVEILAEDGGLWDAIATGVCAALASGGFEMYDTFSACGAALLPDGSIVTDPSATEWNTAKATAVTCAMLNSGNMCFTAQRGSCEPTTALDLVTAALKGTLARKNVISSQLCEQFAF