wanglab/gogpt-training-data huggingface dataset:
Protein: E3 ubiquitin-protein ligase RHA2B (EC 2.3.2.27) (RING-H2 finger A2b) (RING-H2 zinc finger protein RHA2b) (RING-type E3 ubiquitin transferase RHA2B) (Q9ZU51)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid (ABA) signaling and responses to salt and osmotic stresses during seed germination and early seedling development. Acts additively with RHA2A in regulating ABA signaling and drought response. Possesses E3 ubiquitin ligase activity in vitro.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21478367}. Nucleus {ECO:0000269|PubMed:21478367}.
Interaction partners:
- Transcription factor MYB30
- E3 ubiquitin-protein ligase ATL9
- E3 ubiquitin-protein ligase SDIR1
- E3 ubiquitin-protein ligase AIRP1
- E3 ubiquitin-protein ligase MIEL1
- E3 ubiquitin protein ligase RIE1
- Phosphatidylinositol 4-kinase gamma 2
- E3 ubiquitin-protein ligase AIP2
- RING-H2 finger protein ATL56
- Probable E3 ubiquitin-protein ligase ARI9
Sequence:
MGLQGQLSDVSSDSIPLMLLALLATFFRHVRSLLLFPSSAPVVVVTSNLSVLADQLNLNRLFSYRYSDNAASDCIVCLSKLKTGEEVRKLDCRHVFHKQCLEGWLQHLNFNCPLCRSPLLPHHHQGHGSDASISAFPLRSTSTASSH
Protein: Protein Wnt-9a (Protein Wnt-14) (Q8R5M2)
Organism: Mus musculus (Mouse)
Function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development. Plays a redundant role in maintaining joint integrity.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:O14904}. Secreted {ECO:0000250|UniProtKB:O14904}.
Interaction partners:
- Protein-serine O-palmitoleoyltransferase porcupine
- Wnt inhibitory factor 1
- Palmitoleoyl-protein carboxylesterase NOTUM
- Glypican-3
- Cerberus
- Low-density lipoprotein receptor-related protein 5
- Frizzled-2
- Frizzled-1
- Frizzled-8
- Frizzled-9
Sequence:
MLDGSLLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLETEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQYQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLGRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETSLKVGSTTNEATGEAGAISPPRGRASGSGGGDPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCKG
Protein: zeta-carotene-forming phytoene desaturase (EC 1.3.99.29) (2-step phytoene desaturase) (P54979)
Organism: Myxococcus xanthus
Function: Dehydrogenates carotenes in the cis conformation: has cis-to-trans isomerase activity and mediates dehydrogenation of cis-phytoene, producing zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of 2 double bonds at the C-11 and C-11' positions of phytoene.
Interaction partners:
Sequence:
MSASTQGRRIVVVGAGVGGLAAAARLAHQGFDVQVFEKTQGPGGRCNRLQVDGFTWDLGPTIVLMPEVFEETFRAVGRRIEDYLTLLRCDPNYRVHFRDRSDVTFTSELCAMGRELERVEPGSYARYLAFLAQGRVQYRTSLDHLVGRNYAGLRDYLSPRVLARIFQVRAHRRMYADVSRFFQDERLRAAMTFQTMYLGVSPYASPAVYGLLPFTELGVGIWFPKGGLYAIPQALERLAREEGVRFHYGAPVERILTDGGRTRGVRLEGGEVVEADAVLCNADLPYAYEKLLDPKATTLKRKEKLRYTSSGYMLYLGMKRRYPELLHHNVVFGRDYKGSFDDIFEFRVPEDPSFYVNAPTRTDASLAPEGKDALYVLVPVPHQHPDLDWKVEGPKVRAKFFARMAELGFPSLESDIEVERRSSTPDDWAGTFNLARGSGFGLSQNFTQIGPFRPSNQDARVKNLFFVGASTQPGTGLPTVLISARLVTERLMTWAHAQGVSLSPRTAAATPLEGVAA
Protein: Cell cycle checkpoint protein RAD1 (Q4GZB2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSVQCQVAHPYLLLKSLSLLTISKDAWAEVEFTESSVTLDVEGAGQSATATAVLPTSIFSQYTTTGVRFAVHLGMFRNALLLGGPSQLNSMSTSRVVLSYPTKEARLLVELSDGKITLRSKLITQRPKEYPLDLQFSHARILNQVTLPGDAARAAIEDLVTAQCSHAVVTLDPREGVLFRGEGGPYGSALIKIPLNSDVISSIFDGDERVETHVLQSHLVLVCGVRSGGKQRRNTLVPANDFLMGPNSNGGGGYGQQQAAVGGFERLMLQINEARQLSVVHMLRERDIPVTVTLVVSPIYNLHDQ
Protein: CRAL-TRIO domain-containing protein C365.01 (Q9UUC2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MADIPADRKKIVQEGWSRLFSDIEQPSYIQKFPSQESLYVSFFEQCAFDDFDLTLLRFLKARKFVVTDSSDMLANAIVWRQQANLRSIMVRGENGLNQNFVKASMYFIWGQDKKGRAIVFLNLHNFIPPKNTKDMEELKALILYAMENARLFLDSEQNAAKGVLGLVDLTYFSRKNIDLDFARVFAETFQNYYPEILGQALIVGSGFRMALFEGVWSIGKYFLDPEVRSKVTFCKPAQVSGYVDSKYIPLSMHGQFDETKLYERAPPETAGIGKPENYEELDKEYVDAAKEFIRLTREWIYAAGKPQEAEIEEKRKAFKYECKKLWRKGVALRPPNIYQRLGLIDANGHVDWSKA
Protein: LD30157p (Q95RH0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MVAVIQDVIFPIMSFTDSDQELWESDPYEYIRLKFDIFEDYATPVPAAQSLLHSMCKKRKGILPKAMATIMQIITSPNADNKQKDGALHMIGTLADVLLKKASYRDQVESMLTTYVFPEFQNPAGHMRARACWVLHYFCDVQIKNPQVLAEIMRLTTNALLTDKELPVKVEAAIGLQMFISSQDEAPQYVEAQIKEITKELLTIIRETENEDLTNVMQKIVCTFTEQLLPVATEICQHLATTFSQVLESEEGSDEKAITAMSLLNTIETLLSVMEEHPDVLLNLHPIVINVVGHIFQHNITDFYEETFSLVYDLTAKAISPEMWQMLELIYQVFKKDGIDYFIDIMPALHNYVTVDTPAFLSNPNRLLAILDMCKTMLTSSPGEDPECHAAKLMEVIILQCKGQIDSVIHMFVELALSRLTREVQSSELRTMCLQVVIAALYYNPQLLLSILDKMSQQNNDSISAHFIKQWLHDTDCFLGIHDRKLCVLGLCTLISLGEAKPQVLSEVAGKIVPALILLFDGLKRAYESRAQEEEEDEEEEDGDDCEEALSSDEDDMDEMAPDYLDKLAEFAKTKGNESGFEVKAEIKDDDADSDGDAEESVGDLNETGLESFTTPIDDEENESAIDEYWTFKEVITALSAQDQAWYALLTSNLTPEQAKALQEVVVTADQRKAAKESKLIEKQGGFAFPQTAVPTSFKFGS
Protein: Uba3-binding protein but1 (Meiotically up-regulated gene 107 protein) (O42666)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as a negative regulator of the NEDD8 pathway. Has a role in meiosis.
Subcellular location: Nucleus {ECO:0000269|PubMed:14623327, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uba3-binding protein but2
- Uncharacterized protein C23H4.05c
- NEDD8-activating enzyme E1 catalytic subunit
- Ubiquitin-like protein 1
- Sulfiredoxin
- Uncharacterized but2-like protein C27D7.09c
- Catalase
Sequence:
MEIDQNLFQFPISTRDAVHEKNCTLRVKSTKKRRSSTKDEETRGMHPHIKSSFRNGMNHARVIREEDMEVVFEPCFINLSKPVYVVNGIGGINEIHKLPILFSSFVLCFFGNVSGDYGYVDNVPLHISVISHFYPCLQSYNTDVIGITTDTVENICQWKAHLPRALQFSLPVISDSNNEICREMGMLHPLGGAKLALDAIVIIDSIGRRRDILPIRTTTCVSTLITAVQETVRFLAIENGRLL
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (F4IK85)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Phospholipase A2-beta
- DExH-box ATP-dependent RNA helicase DExH10
- Cycloartenol synthase
- GATA transcription factor 18
- Profilin-1
Sequence:
MVKMVDGERRDESVAIAIDRDKGSQAALKWAVDNLLTPGETLTLIHVKVKQTLANNGTQPNKSGDDVKELFLPFRCFCTRKDINCEEVVLENVDAAEGIIEYVQENAIDILVLGASKITLLKRLKAVDVTNAVIKGAPNFCTVYAISKGKISSVRSATSSPPPLCTIRPQLPARSSNANNNNFSPRAQRRLQSVQSIQDEIEIKSPYLRKEYDQGTYQALVSDSDLSFVSSDRPSMDWFEDNRSNYATSSSSSEKQSIDLCSSYSAFSTSSQESGRLSSLSMYSQDDVESEMRRLKLELKYTMDMYNSACKEAIAAKKTTIELHKWKEERKHKLEEAILAKEAAMAIAENEKAKSRAAMEALEAAHRMAETEAQKRKQIETAALREVEHENKAMHALPHSNRMYRKYTIEEIEQGTTKFSDSHKIGEGSYGTVYKGTLDYTPVAIKVVRPDATQGRSQFQQEVEVLTCIRHPNMVLLLGACAEYGCLVYEYMSNGSLDDCLLRRGNSPVLSWQLRFRIAAEIATSLNFLHQLKPEPLVHRDLKPANILLDQHMVSKISDVGLARLVPPTIDDIATHYRMTSTAGTLCYIDPEYQQTGMLGTKSDIYSFGIVLLQILTAKTPMGLTNQVEKAIEEGNFAKILDPLVTDWPIEEALILAKIGLQCAELRRKDRPDLGTVVLPGLKRLMNLAEENMSITRPSS
Protein: GEO08224p1 (Odorant-binding protein 56e) (RH03850p) (Q7K088)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- General odorant-binding protein 57e
- Odorant-binding protein 56g
Sequence:
MKVFFVFAALAALSLASAVGLTDSQKAEAKQRAKACVKQEGITKEQAIALRSGNFADSDPKVKCFANCFLEQTGLVANGQIKPDVVLAKLGPIAGEANVKEVQAKCDSTKGADKCDTSYLLYKCYYENHAQF
Protein: Cytochrome b5 (Q8SY77)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004131}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004131}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004131}. Microsome membrane {ECO:0000256|ARBA:ARBA00037877}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00037877}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00037877}.
Interaction partners:
Sequence:
MSKEIRLATVNEHNKATDLWVVIDNKVYDVTKFRLEHPGGEESLVDEAGRDATKAFNDVGHSSEAREMLKKYYIGDLAAADIKKKSPIR
Protein: Kin of IRRE-like protein 1 (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1) (Q80W68)
Organism: Mus musculus (Mouse)
Function: Required for proper function of the glomerular filtration barrier. It is involved in the maintenance of a stable podocyte architecture with interdigitating foot processes connected by specialized cell-cell junctions, known as the slit diaphragm. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Predominantly located at podocyte slit diaphragm.
Interaction partners:
- Nephrin
- Podocin
- Tight junction protein 1
- CD2-associated protein
Sequence:
MTLESPSTRLMTCQSSLLPEKPRFLSQKMWAPHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGAGILVVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASISTATRVMKAIYSSFKDDVDLKQDLRCDTIDTREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTHV
Protein: Glucocorticoid receptor (Nuclear receptor subfamily 3 group C member 1) (A0A494C0P1)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTHSDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK
Protein: Small COPII coat GTPase SAR1A (EC 3.6.5.2) (Q559R0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9NR31}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9NR31}. Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q9NR31}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9NR31}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9NR31}. Note=Active at endoplasmic reticulum exit sites (ERES) where it inserts into the membrane and recruits the remainder of the coat protein complex II/COPII. {ECO:0000250|UniProtKB:Q9NR31}.
Interaction partners:
- Protein transport protein SEC31
- WD-40 repeat-containing protein
- Protein SEC13 homolog
- Protein transport protein SEC23
- Protein transport protein SEC23
- Small COPII coat GTPase SAR1B
- Protein transport protein SEC24
- Protein transport protein SEC24
- GPI mannosyltransferase 1
- Uncharacterized protein
Sequence:
MFLFDWFWNVLSFLGLYNKNAKILFLGLDNAGKTTLLGVLKDGRLSSYLPTFHPTSEELAMGNIRFKAFDLGGHESARRLWKDYYPSVDAIVYLIDSSAQDRFVESKKELDSLLSSDELANVPFLILGNKVDIGNTSEEKFRASLGLTQTTGKGKTTLNGVRPIEVFMCSVVKRYGYAEGFRWLANYL
Protein: Ribosomal protein S9 (Q57W62)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Treble clef zinc finger domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Small ribosomal subunit protein uS5 C-terminal domain-containing protein
- Mitochondrial ribosomal protein S18
- 30S Ribosomal protein S17, putative
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MQKLLSPRTARHARLFRLAGKLADSGSPGVPKSDGERLVWVNSHVRRDKDISLSQEEERIRELMMPLEVGENSFAANGQATHGNLFYFREYPMYPGEYVPAEHNTLSSLRDELRLDLTAQSLKEAWMRVSGGVYFQSVDEYYASVDGLDAEQIGEVLAALFPELNCYEAQALVQRTLECISRPVSAASRQLSRTITAEAVGLDNAPGHYTNFLEWMGRLTETRAFKTEHALFEFSRRKFNRDDVRVMFENYRLMSKATLLADSADSYSHFYTVLKDFARKVAGEDSRHQIGVRIDEAEVDPETGIAVGRGCADGEKYHFTALLRENRDHNGIITVMGKPLSLVLDNKAWLMEMVLMPFDEANLDYRDFDVHIVSEGHAMPSIANEIAAFALRMAVANALVKLIPLTRIPLKKSGLLSVDRRRERGQFPGYLDGKKVKRRFAKR
Protein: Kinetochore protein SLK19 (Synthetic lethal KAR3 protein 19) (Q08581)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a role in spindle assembly and stability. Required to ensure a timely exit form mitosis. Essential to maintain pre-anaphase spindle polarity. Associates to the plus ends of the microtubules at the kinetochore and spindle midzone. A component of the FEAR (CDC14 Early Anaphase Release) network which promotes CDC14 release from the nucleolus during early anaphase. Required for proper chromosome segregation during meiosis I where it prevents premature sister chromatid separation.
Subcellular location: Chromosome, centromere. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Spindle midzone during anaphase. During meiotic prophase localizes to the centromere and remains there until anaphase I.
Interaction partners:
- Separin
- Protein phosphatase PP2A regulatory subunit B
- Tyrosine-protein phosphatase CDC14
- Cell cycle serine/threonine-protein kinase CDC5/MSD2
- Sporulation-specific protein 12
- Guanine nucleotide exchange factor LTE1
- Cell division control protein 15
- Protein TEM1
- Protein BNS1
- Kinesin-like protein CIN8
Sequence:
MNEVPTTPVRLILGQAQQREQNSENCSQERNPRTFNSEPDSSFNSPGSSQFVIHPHEPLEKEKDEKQDLDRSIDYGRSSALNNKNNANPLENIDINKMFDDKKSDSGTNDDKGGASTSDKHVLALNYSPIRVEMNSSEKRSDKNVDVDENDKEGSHINKKLKLQLESVPDLKQSSTKDIINDKEEIMSSPMAIDMIETNISPNKFIINDGVERNDSFNINTDTLKLENDINEKQQEEDFIKSNSNNVVNIDNAYKEKEDEENDITNSHINRLTPLYETSARESNSNEEGRNDYDDDNQLDIRHDNFQIVAKRNEELTDQIYHLNQMLNSLISKNESLSFQYEKLNKNHQLLIDLTNEKLDKLNTERESDIAKVEKFKKRIKELNTEIKVLNSNQKILQEKFDASITEVNHIKGEHENTVNTLQQNEKILNDKNVELENMKAELKGNNDKLSEYETTLNDLNSRIVQLNDKIESTDIVLKSKENELDNLKLSLKETLSISKDFNDSDLIGQINELISTKNNLQQKMDDLNNLNDDNLKVVQDKLIKNEETLKLKEAEIDSLNSEMDELKKQITSKDDEFKMWQSKYETVEDEAKIRNAEVTELNGDIEDLKESKLHLEETITELENKVHKLENECELEKQKFEKTSLELESLQLKNSNIQAEHIKELENLHENLISLQNELKISSDRITTLTKENEVLMEQNNNNNNSVTLSNDQKDRDDEKIKSLGKQVQDWKEKYEAKEKDTNKRLKLLAEDLYIQYSSKHEQKVKLLKKGYENKYQNKFDQLNLENKTLSEEIEQLNKQLSSEREEKQELLKLLENEKK
Protein: Gap junction protein (A0A654ICK0)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, gap junction {ECO:0000256|ARBA:ARBA00004610}. Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}.
Interaction partners:
Sequence:
MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPI
Protein: Cyclin dependent kinase 1 (F1NBD7)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHPNIVCLQDVLMQDARLYLIFEFLSMDLKKYLDTIPSGQYLDRSRVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNDVWPDVESLQDYKNTFPKWKPGSLGTHVQNLDEDGLDLLSKMLIYDPAKRISGKMALNHPYFDDLDKSTLPANLIKKF
Protein: Rh family, C glycoprotein, like 1 (Rhcgl1 protein) (A8E4T4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MVKNTNIRISLPAVCFVWQIAMIILFGVFIRYNEESDSHWIETRKKNNISTDLENDFYYRYPSFQDVHVMIFVGFGFLMTFLKRYSFGSVGFNFPIAAFGIQWALLMQGWFHSFDKEDLKIKIGVENLINADFCVAGCLIAYGACLGKVSPVQLMVLTLFGVTLYAVEEYIILDLLHVRDAGGSMVIHTFGAYYGLTISWVLYRPFLSQSNHLQRSVYHSDVFAMIGTLFLWMFWPSFNSAIADHGDGQHRAAINTYLSLAASVLTTFALSSLSKKYGKLDMVHIQNATLAGGVAMGTASEFMITPYGSLIVGFCSGIVSTVGYVFLTPLMEKTLKIQDTCGVHNLHAMPGVIGGIVGAVTAACASESVYGHEGLINMFGFEGKVNRTASVQGGYQAAGIFVAIAFGLVGGALVGGILKLPIWGDPTDSNCFDDDIYWEVPEEEDENIPAFGHQNMHRVERTPDAHHRSHV
Protein: Ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (EC 3.6.1.-) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2) (O35795)
Organism: Rattus norvegicus (Rat)
Function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Nucleoside-triphosphatase, cancer-related
- Ectonucleoside triphosphate diphosphohydrolase 1
- Adenylate kinase 8
- Ribonucleoside-diphosphate reductase
- Adenylate kinase isoenzyme 5
- Adenylate kinase 9
- Nucleoside diphosphate kinase
- Nucleoside diphosphate kinase homolog 7
- Ribonucleoside-diphosphate reductase subunit M2
- Ectonucleoside triphosphate diphosphohydrolase 3
Sequence:
MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL
Protein: Tropinone reductase homolog At1g07450 (EC 1.1.1.-) (Q8RX32)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- AGAMOUS-like 99
- MADS-box family protein
- AGAMOUS-like 89
- At3g12510
- Protein STRICTOSIDINE SYNTHASE-LIKE 2
- MADS-box family protein
- MADS-box family protein
- strictosidine synthase
- Protein STRICTOSIDINE SYNTHASE-LIKE 11
- AGAMOUS-like 91
Sequence:
MDINRWSLQGMTALVTGGSKGIGYAIVEELVGFGARVHICDIDETLLNECLSGWHAKGFEVSGSICDVSSRPQRVQLMQTVSSLFGAKLNILINNVGKYILKPTLESTAEDFSSLMATNLESAYYISQLAHPLLKASGNGNIVFISSVTGVVSGTSTIYGVTKGALNQLARDLACEWASDNIRANSVAPWVTATSLVQKYLEDEIFAEAMFSRTPLGRACEPREVASLVTFLCLPAASYITGQTICIDGGFTVNGFSYKP
Protein: Gonadotropin subunit beta-2 (GTH-II-beta) (Gonadotropin beta-II chain) (P07732)
Organism: Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)
Function: Involved in gametogenesis and steroidogenesis.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MLGLHVGTLISLFLCILLEPIEGSLMQPCQPINQTVSLEKEGCPTCLVIRAPICSGHCVTKEPVFKSPFSTVYQHVCTYRDVRYEMIRLPDCPPWSDPHVTYPVALSCDCSLCNMDTSDCTIESLQPDFCITQRVLTDGDMW
Protein: Nuclear pore complex protein NUP155 (Nucleoporin 155) (F4HXV6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Major component of the nuclear pore complex (NPC).
Subcellular location: Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
Interaction partners:
- Protein SEH1
- Nuclear pore complex protein NUP54
- Nuclear pore complex protein NUP107
- Nuclear pore complex protein NUP35
- Nuclear pore complex protein NUP205
- Nuclear pore complex protein NUP160
- Nuclear pore complex protein NUP88
- Aladin
- Nuclear pore complex protein NUP93A
- Nuclear pore complex protein NUP85
Sequence:
MSQDDEIVMRDVTSAGICIGDRIGREAASQLDLEEALEASRYASHPYSTHPREWPPLIEVGETWELPSVLIERYNTAGGEGTALCGIFPEIRRAWASVDNSLFLWRFDKRDGQCPEYSGEEQAICAVGLAKCRPGVFVEAIQYLLVLATPVELVLVGVCCTEGPDGRDPYAEISVQPLPDYTISSDGVTMTCVTCTNKGRIFMAGRDGHIYELLYTTGSGWNKRCRKVCLTAGVGSMISRWVVPNVFKFGAVDPVVEMVVDNERQILYARTEEMKLQAYVSGPNGEGPLKKVAEERNLLNQKDLSQGNRQSAVAGRSNKPSIVSISPLSMLESKWLHLVAALSDGRRMYLSTSSSGSGSTISFSGFNNHRQTPNCLKVVSTRPSPPLGVGVGLGFGAASVAGRTQNDDLSMKIETAYYSVGTLVLSDSSPPAMSSLLVVSRDSSVHSQAGSSSGPSSRSSRALREVVSSLPIEGRMLFVADVLPSPDTAATIQSLYSELEYCGVEVSGESYEKACGKLWARSDLSTQHILPRRKIVVFTTMGMMELVFNRPVDILRRLLESNSPRSLLEDFFTRFGVGEAAAMCLMLAARIINFEDLISNIVADKAAEAFEDPRIVGMPQFDGSSGLSNTRTATGGFSMGQVVQEAEPIFSGAHEGLCLCTSRLLFPLWELPVMSKKTSSDTMSEDGVVICRLSTSAMHVLESKIRSLEKFLRSRRNQRRGLYGCVAGLGDVTGSILYGTGSELGATERNMVRNLFGAYSNGGESANKRQRLPYSPAELAATEVRAMECIRQLLLRSAEALFLLQLLSQHHVARLVQELDANLKQALVQLTFHQLVCSEEGDQIATRLISAVMEYYTGSDGRGTVDDISPRLREGCPSYFKESDYKFYLAVERLERAALTSDAEEKENVAREAFSFLSKVPGSADLQTVCKRFEDLRFYEAVVCLPLQKAQALDPAGDAFNDQLDASIREHALAQRKQCYEIIANALRSLASPLASPTLDEASRSQYICQIVHLGVQSTDRAFREYLYKAMIELHLENELLEYGGPDLVPFLQNAGSHSESQVGAVSTGSSPLGHSGTQISSDQAKYFDLLAKYYVSKRQHVLAAHVFLRLAERRAISLGDSPTLERRRDDLSQAVLQAKNASNSDGLVGSAQGVSDSGLLDLLEGKLAVLQFQIKIRDKLEAIASNFESSVAMQDSDQNGQVLDGDSSDDTNLANAANEMAMEVSSELKSVTQLYNEYAVPFELWEICLEMLYFANYSGDADSSIIRETWARLIDQALSQGGIREACAVLKRVGSHIYPGDGVVLPLDVLCLHLERAALERSERIENVRDEDIAKALLAACKGAAEPVLNAYDRLLSNAAVVPSPNLRIRLLRSVLVVLREWAMSVLSDRMGSSPTRSSLILGGSFALENKAALNQGARDKIANAANRYMTEVRRLALPPNKTDGVYAGFKELDESLLSPFSF
Protein: Uncharacterized protein (Q38CI0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 39S ribosomal protein L28
- LIM zinc-binding domain-containing protein
- Large ribosomal subunit protein mL43
- NADH dehydrogenase 1 beta subcomplex subunit 9
- Large ribosomal subunit protein uL29m
- KOW domain-containing protein
- Large ribosomal subunit protein mL46
- Uncharacterized protein
- Uncharacterized protein
- Ribosomal protein L30 ferredoxin-like fold domain-containing protein
Sequence:
MLYTRRLMTTGGSATADGAVSYSKGSYHIVPKKYTVGKRIAVRSYLDRNRTELSDRTYMPQKAWFEPYTPKKFDMEHQRISHNFYNLETKLIWTAFDTPELIGILLHDETIKGAPHLYDAEFLESAVHWTRESRYWRCIGITKPFYNKTTLRAQCWHDRGLQVGTLVFSQAMRDALMDLERAVRRKELGLEPNYVWDRWGPVGFIDGARTDHLPRFAHNPYVDPDGVEVTEVDIAPFNTHEQIKERYGAFIDPDLRPFEGVFRAPSHGALTLDDVPHQEAVRLYRDLMEKADMPVMLGNGAEIPPMDLRALFHLSANPERMKAASELSSWREVRGMLAPVQEVCDEKVEALRLMENTRHDVARVRTFYEEKCGFSDFMRTPDKVITAAVLCYLQELQRICTERDWGKPLARCLTDLERVNVMGKDAFLVYRHIEDAILDKKRRVWATRFAGEANEESTLDYLLENFGRRTEQTRNVGTTGTEFDREQEPIGRQVQRRVLDSDKASKLAEVRQKRGKMWSNKKSVFDSLHQKQLQNVTYGVH
Protein: Protease B inhibitor 2 (Proteinase inhibitor I(B)2) (P0CT04)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cytosolic inhibitor of vacuolar proteinase B (yscB), probably regulating protease B activity during limited proteolysis. PBI2 is a component of the LMA1 complex, which is involved in the facilitation of vesicle fusion such as homotypic vacuole and ER-derived COPII vesicle fusion with the Golgi.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:1100120, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:9159115}.
Interaction partners:
- Uncharacterized protein YHR138C
- ATPase-stabilizing factor 15 kDa protein
- Vesicular-fusion protein SEC18
- Cerevisin
- Alpha-soluble NSF attachment protein
Sequence:
MTKNFIVTLKKNTPDVEAKKFLDSVHHAGGSIVHEFDIIKGYTIKVPDVLHLNKLKEKHNDVIENVEEDKEVHTN