wanglab/gogpt-training-data huggingface dataset:
Protein: AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4) (O00189)
Organism: Homo sapiens (Human)
Function: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (By similarity). Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal (By similarity).
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:20230749, ECO:0000269|PubMed:29180427, ECO:0000269|PubMed:32073997}; Peripheral membrane protein {ECO:0000305|PubMed:32073997}. Early endosome {ECO:0000269|PubMed:20230749}. Note=Found in soma and dendritic shafts of neuronal cells. {ECO:0000250|UniProtKB:Q2PWT8}.
Interaction partners:
- AP-4 complex subunit beta-1
- AP-4 complex subunit epsilon-1
- AP-4 complex subunit sigma-1
- AP-5 complex subunit mu-1
- AP-2 complex subunit beta
- AP-2 complex subunit alpha-1
- AP-1 complex subunit sigma-1A
- AP-5 complex subunit zeta-1
- AP-5 complex subunit sigma-1
- Osteopontin
Sequence:
MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIRI
Protein: Nucleolar protein 11 (J3QLQ6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAALEEEFTLSSVVLSAGPEGLLGVEQSDKTDQFLVTDSGRTVILYKRFGRTRWFTPVIPELREAQVSDQKPLGSWSVKQGQIITCPAVCNFQTGEYVVVHDNKVLRIWNNEDVNLDKVFKATLSAEVYRILSVQGTEPLVLFKEGAVRGLEALLADPQQKIETVISDEEVIKWTKFFVVFRHPVLIFI
Protein: NAD-dependent epimerase/dehydratase family protein (Q54KL2)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Small ribosomal subunit protein eS30
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS10
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein eS19
Sequence:
MAEHLKNNKIVVTGATGYIASAIIKELLLDDEIEKVVAIVRDKSNVDKHKFLLELKNAEKKLEIESGDLQNADYDSIFAGATGILHVASPYVYKADNAQRDIIEPAIQGNLRVLEAASRHQSTIKKVIITSSTAAIIDLEKKKEQYDESDWNDSSNISNPYSYSKYLAEKATWSYKENNADKVKSFEIIIINPAFVLGPPVEGYPSLNTSLTTFRNSLMNIGDKVVTNRMVGLIDIRDVVKAHIKALKSTENFDHKRYLMANTVISFAGMGELVKEIFPQYQIDPTPIDPSIQVHQHKLTSISPLKLTEPYIDLKTTLTDCVNYLINSKNFNPKLKQ
Protein: Transmembrane protein 53 (Nuclear envelope transmembrane protein 4) (Q6P2H8)
Organism: Homo sapiens (Human)
Function: Ensures normal bone formation, through the negative regulation of bone morphogenetic protein (BMP) signaling in osteoblast lineage cells by blocking cytoplasm-nucleus translocation of phosphorylated SMAD1/5/9 proteins.
Subcellular location: Nucleus outer membrane {ECO:0000269|PubMed:33824347}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MASAELDYTIEIPDQPCWSQKNSPSPGGKEAETRQPVVILLGWGGCKDKNLAKYSAIYHKRGCIVIRYTAPWHMVFFSESLGIPSLRVLAQKLLELLFDYEIEKEPLLFHVFSNGGVMLYRYVLELLQTRRFCRLRVVGTIFDSAPGDSNLVGALRALAAILERRAAMLRLLLLVAFALVVVLFHVLLAPITALFHTHFYDRLQDAGSRWPELYLYSRADEVVLARDIERMVEARLARRVLARSVDFVSSAHVSHLRDYPTYYTSLCVDFMRNCVRC
Protein: NADH-ubiquinone oxidoreductase chain 6 (EC 7.1.1.2) (NADH dehydrogenase subunit 6) (P03926)
Organism: Rattus norvegicus (Rat)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03924}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase chain 5
- NADH dehydrogenase 1 alpha subcomplex subunit 1.
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase 1 beta subcomplex subunit 6
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
Sequence:
MTNYMFILSLLFLTGCLGLALKPSPIYGGLGLIVSGCIGCLMVLGFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWGSNWFIFSFFVLGLFMELVVFYLFSLNNKVELVDFDSLGDWLMYEIDDVGVMLEGGIGVAAIYSCATWMMVVAGWSLFAGIFIIIEITRD
Protein: Cell surface protein, putative (Q4WXC4)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
Sequence:
MVNSGIALLALAGPALGGIVPNKGNDEGHSGYPGHTPPTKWPATAEPHWVTRTATYLTTTCPVSHTKVTSGTKTLTIPITLTSTITVTTTTVEDSNTETRVVVPTGTVPNHPLVPTSVPTSVPTSVPTSVPTQNATSIPTFVPTQNATSVPTSVPTQNATTIVPPPKVVPTGVPGQNTTVVPPPRPAPFTNSTVPPPVQPVPVAPGQPTAPSQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSAPGQPSAPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSAPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSVPGQPSAPEQPSVPGQPSVPEQPSAPEQPSVPGQPTAVSPPPAETALTGSASQFEPAAGLLAGIWVVMLML
Protein: Citrate synthase (A0A060XAB1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}.
Interaction partners:
- malate synthase
- Malate dehydrogenase
- Malate dehydrogenase
- Aconitate hydratase, mitochondrial
- Aconitate hydratase, mitochondrial
- Aconitate hydratase, mitochondrial
- Aconitate hydratase, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Cytoplasmic aconitate hydratase
Sequence:
MSLLSAYRFTPKLLNSTKSTACLFAASRNATTSTNLRDVLLDLVPKEQSRIKNFKTQYGKTNIGSITVDMIYGGMRGMKGLVYETSVLDADEGIRFRGYSIPECQQLLPKAPGGAEPLPEGLFWLLVTGQVPTEEQVNWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQFSAAITALNSESSFARAYSEGVNKAMYWEFVYEDSMDLIAKLPCVAAKIYRNLYREGSSIGAIDSSLDWSHNFTNMLGYSDATFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKEMGGEVSDEAMRDYIWNTLKSGRVVPGYGHAVLRRTDPRYTCQQEFAFKHLPDDPMFKLVHQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMNLVGANKSG
Protein: Aconitate isomerase (AI) (EC 5.3.3.7) (A0A0A1H8I4)
Organism: Pseudomonas sp
Function: Involved in assimilation of trans-aconitic acid. Preference for cis-aconitic acid is 14-fold higher than for trans-aconitic acid. Not active on intermediates of tricarboxylic acid (TCA) cycle including citric acid, succinic acid, fumaric acid, and 2-oxoglutaric acid or on other dicarboxilic acids including itaconic acid, formic acid, citraconic acid or maleic acid.
Interaction partners:
Sequence:
MFPRLPTLALGALLLASTPLLAAQPVTTLTVLSSGGIMGTIREVAPAYEKATGVKLDIAAAPSMGDTPQAIPNRLARNEPADVVLMVGSALDKLVASGQVAKDSRVDLGQSFIAMAVRQGAPKPDISNMDAFKQTLEKAQSVAYSDSASGVYLSRILFPRMQLDKSFMAKARMIPAEPVGAVVARGEAQLGFQQLSELKAVPGIDIVGLIPDQAQKMTLYSGAMVSKSQHPEAARALLQYLASKDAAKAIEDSGLKPVPAQP
Protein: Auxin-responsive protein IAA14 (Indoleacetic acid-induced protein 14) (Q7Y1H8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Auxin response factor 7
- Auxin response factor 11
- Transport inhibitor response 1-like protein Os05g0150500
- Auxin response factor 3
- Auxin response factor 9
- Auxin response factor 15
- Auxin response factor 2
- Auxin response factor 14
- Auxin response factor 1
- Auxin response factor 16
Sequence:
MAAESIDAELRLGLPGSGGGDGVAAKKRRSASSTVKSEASGTACCGGAGARDVEDGASPASKVQVVGWPPVGSYRRSTFQSSSSSTAAAAKGKGGGETDQGRKNKGGGLYVKVSMDGAPYLRKVDLRMYGGYRELRDALDALFGCFSADASASAAHFAVAYEDKDGDLMLAGDVPWDMFISSCKKLRIMRGSEAR
Protein: Globin c2 (RCG34342, isoform CRA_a) (A0A1K0FUH3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MVLSAADKTNIKNCWGKIGGHGGEYGEEALQRMFAAFPTTKTYFSHIDVSPGSAQVKAHGKKVADALAKAADHVEDLPGALSTLSDLHAHKLRVDPVNFKFLSHCLLVTLACHHPGDFTPAMHASLDKFLASVSTVLTSKYR
Protein: Splicing regulator RBM11 (RNA-binding motif protein 11) (Q80YT9)
Organism: Mus musculus (Mouse)
Function: Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1 (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000250}. Nucleus speckle {ECO:0000250}. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles. {ECO:0000250}.
Interaction partners:
Sequence:
MFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTLCKDRDGKPKSFGFVCFKHPESVSYAIALLNGIRLYGRPINVQYRFGSSRSSEPANQSFESCAKINSHSFRNDEMAGRPSFPVPFFPITSAALPQEYFFFQKMPWYAHSPVLQPPFCEMPAPLPNSVPGSCALNHSPGPEAGPSSYEWTHQPPSDPDLYPRNKRKRQRPDSDSDSSSEDKRGNEGSQKCRKCKKKKRY
Protein: General transcription factor IIIC subunit 5 (Q5T7U0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSDFQYLAVHTEAGGKHTSMYDKVLMLRPEKEAFFHQELPLYIPPPIFSRLDAPVDYFYRPETQHREGYNNPPISGENLIGLSRARRPHNAIFVNFEDEEVPKQPLEAAAQTWRRVCTNPVDRKVEEELRKLFDIRPIWSRNAVKANISVHPDKLKVLLPFIAYYMITGPWRSLWIRFGYDPRKNPDAKIYQVLDFRIRCGMKHGYAPSDLPVKAKRSTYNYSL
Protein: Inducible metalloproteinase inhibitor protein [Cleaved into: IMPI alpha] (P82176)
Organism: Galleria mellonella (Greater wax moth)
Function: Inhibits thermolysin, bacillolysin and pseudolysin, B.polymyxa metalloprotease and human MMP1 and MMP3. No activity on trypsin or cysteine protease papain.
Interaction partners:
Sequence:
MKCLLYLCLWCYCVLVSSSIVLICNGGHEYYECGGACDNVCADLHIQNKTNCPIINIRCNDKCYCEDGYARDVNGKCIPIKDCPKIRSRRSIGIPVDKKCCTGPNEHYDEEKVSCPPETCISLVAKFSCIDSPPPSPGCSCNSGYLRLNLTSPCIPICDCPQMQHSPDCQ
Protein: Alpha-mannosidase (EC 3.2.1.-) (Q9VKV1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSAKTSVWLVFFCALGCLIHDADLRSIQPKASQCGYQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSANLGEEADLFSGALYNNYQAPDGFCFDILCNDAPIIDGKHSPDNNVKERIDTFLDFAKTQSQYYRTNNIIVTMGGDFTYQAAQVYYKNLDKLIRYGNERQANGSNINLLYSTPSCYLKSLHDAGITWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSALAPKKPEEFDPHLTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGATTRNALNQLTVQSKDNVKDTSAKYVFEFKTCALLNITSCPVSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVPIPQVLIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLDSTEGNTRSKALPKRTSSVTVIGNSHIQLGFDTNGFLSEVTADGLTRLVSQEFLFYEGAVGNNAEFLNRSSGAYIFRPNENKIHFATDQVEIEVYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGPIPIDDGIGKEVITRFNSDIASDGIFRTDSNGREMIKRKINHRDTWSVKINEAVAGNYYPITTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDAFGVGEALNETEYGDGLIARGKHHLFFGKSTDREGVSLKGIERLTQLEKLLPTWKFFSNMEDYSADEWQTAFTNIFSGISLVLPKPVHLLTLEPWHENQLLVRFEHIMENGEDASYSQPVQFNVKNVLSAFDVEGIRETTLDGNAWLDESRRLQFAPDPEEAAFNTYATFSQPAESVHLLSAEKPMLGVKYADEALPAGQLGAESNRIRRETETRQEKKDEGRSSKSTEGPYNSFKSDSSNQEYIIELSPMEIRTFIVYLTPA
Protein: Retinoic acid receptor alpha (Retinoic acid receptor, alpha, isoform CRA_e) (A8MUP8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MMSQTMTQAGVSFRHSVRAAQCHTRVPNTWPRATRPYASCRRSPRLRGRWPGSAGQGAGGRAPRAGWRAGDVTGSAIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
Protein: PLASMODESMATA CALLOSE-BINDING PROTEIN 1 (AtPDCB1) (Glucan endo-1,3-beta-glucosidase-like protein 2) (Q9FNQ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Able to bind (1->3)-beta-D-glucans (laminarin). Probably involved in cell-to-cell trafficking regulation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19223515}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:19223515}. Cell junction, plasmodesma {ECO:0000269|PubMed:19223515}.
Interaction partners:
- Plasmodesmata-located protein 1
- Plasmodesmata-located protein 5
- Glucan endo-1,3-beta-glucosidase 10
- Callose synthase 3
- RING-type E3 ubiquitin transferase
- Choline transporter protein 1
- At3g52060
- Remorin
- Plasmodesmata-located protein 2
- Plasmodesmata-located protein 3
Sequence:
MAALVLSLLLLSLAGHSSASWCVCKTGLSDTVLQATLDYACGNGADCNPTKPKQSCFNPDNVRSHCNYAVNSFFQKKGQSPGSCNFDGTATPTNSDPSYTGCAFPTSASGSSGSTTVTPGTTNPKGSPTTTTLPGSGTNSPYSGNPTNGVFGGNSTGGTTGTGINPDYTTDSSAFALKNSSKLFICLLLIASSGFCSFLML
Protein: Trafficking protein particle complex subunit-like protein (F4JXM9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Tetratricopeptide repeat
- Trafficking protein particle complex subunit
- Tetratricopeptide repeat
- Trafficking protein particle complex subunit 2-like protein
- SNARE-like superfamily protein
- Trafficking protein particle complex subunit
- Transport protein particle
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Trafficking protein particle complex II-specific subunit 130 homolog
Sequence:
MEEYPEELRTPPVSLVALFGYAELHASITKYLHSQQPPINALAFPDFSQISLLLAHDDQISRTSSFRDPLSVSDSASPIPSRCGGILKRDWLLKHRTKVPALVAAFFPSHHIFGDPTQWLQVCSDLDSLKSVIRPKNIKLVVVVVQSSPHEDISDDRLVALRKRAELDSKYVLFFNSSIVSELTLSLSRLASAFAELALSYYREEGRRIKSRIEKRSSNSLDLNVRYCFKVAVYAEFRRDWGEALKFYEDAYHSLHEMIGTSTRLPAIQRLVEIKIIAEQLHFKISTLLLHGGKLIEAVTWFHQHKTSYEKVVGSTEFIFLHWDWMSRQFLVFAELLETSSATGQSLTSSNQGTAEISLTEFEFYPAYYYQLAAHYLKDKKSALELLLSMSEIAQEIDSSSASITPSVYVGQFAQLLEKGEAITLHSITDEEYTRYTISEAKRVQDSLQIIAWLKRSYESFTNLKAQRMAALCAFEVAREYFDLADPNNAKFFFDIAANLYRQEGWVTLLWEVLGYLRECSRNLDALKDFVEFSLEMVALPVTSYENSGNLRNKNYGPGGPATISGRESIHQEVFTLVCREAELLSSTEGSGFKLATDSPLHLEIDLVSPLRPVLLASVAFHDQMIKPHALCSFTLSLLSHLPLPVEIDHLEVQFNQSTCNFVIRNSQRPLWASASNTVKSGSQVENAPLLVLVPNNWLRLTYAIKSEQSGKLECLSVLAKLGPLFTICSRAESPAAMEDLPVWKHENRVESLPTKDPVLAVFGQKATQVDEPEPQVDVSLGASGPALVGEDFAMPIVVTSKGHAVYSGELKINLVDVGGGGLFSPREAEPFSLESHHVEICGIDGAEGNNESESETGSIKKIQQSFGLVSVPYLKEGESWSCKLEIKWHRPKPVMLFVSLGYLPHGSEANTQKVHIHKSLQIEGKMPLLISNRFMLPYRRDHLLLNRIKPAPDSEDVSSLPLNEKSVLVVSAKNCSEIALKLVSMSIEFDDEQGETSCLIQQGGGCGDSPSSANLAPGEEFKKVFTVIPTTRTPKLGLGSIHLKWRREGGNITEAYVSTKHKLPEVNVEASPLVMSLDSPPYAILGEPFTYAVRICNQTQLLQEAKFGLADAQSFVLSGSHSNTVSVLPKSEHVLSYKLVPLTCGEQQLPKITLTSARYAAEFQPSAVASSVFVFPSAPQAEKAISTSK
Protein: Glucose-6-phosphate exchanger SLC37A1 (Glycerol-3-phosphate permease) (G-3-P permease) (Solute carrier family 37 member 1) (P57057)
Organism: Homo sapiens (Human)
Function: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21949678}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MARLPAGIRFIISFSRDQWYRAFIFILTFLLYASFHLSRKPISIVKGELHKYCTAWDEADVRFSSQNRKSGSAAPHQLPDNETDCGWAPFDKNNYQQLLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFGMLASGAFTALFGLGYFYNIHSFGFYVVTQVINGLVQTTGWPSVVTCLGNWFGKGRRGLIMGVWNSHTSVGNILGSLIAGYWVSTCWGLSFVVPGAIVAAMGIVCFLFLIEHPNDVRCSSTLVTHSKGYENGTNRLRLQKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILPGDGGSGTAAISFTGALKIPGVIEFSLCLLFAKLVSYTFLFWLPLYITNVDHLDAKKAGELSTLFDVGGIFGGILAGVISDRLEKRASTCGLMLLLAAPTLYIFSTVSKMGLEATIAMLLLSGALVSGPYTLITTAVSADLGTHKSLKGNAHALSTVTAIIDGTGSVGAALGPLLAGLLSPSGWSNVFYMLMFADACALLFLIRLIHKELSCPGSATGDQVPFKEQ
Protein: ORC1/DEAH AAA+ ATPase domain-containing protein (Q38AG6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAAQTPRKEVGVDLRDELDADVECGSGYISIFGPPGSGKTTMLLQYLTSREHHVRNMKRSFLLEYVTGRALAGDSLRRLAWRLLPQTKRRRTECSHLQFGLLVRQWLDNAVEGSELHFVVDDADEVEEGAEGINQWLSVCVGGSQQPCNSNVVCLWVVSQMPLRLSNCFRFHFVARPDASVVQSWLNTLFATNASPPGADAEANTPSLTLEEAHNITKGAVEYYMTHLPMRASIVTQDMRQLLQRVHQILPFLVAHAVVGRLNAMHYSTVWGRWRELSSSVATAPSGALVGSRGDPLVAVLRRIGCSAMLWALSAFYCGAVPKSKHALVFGDEKLARRTNSTEVNAASHKAAVLSSLAHVVHLPRLMLVYRSLLNICVNLQDPLEFVPAEIAVQHHQTLVSWGLMVPTTHSTKGYHCHIPVTSAISLSQHLSLNLYDLIPR
Protein: Cookie monster (Q9W2C1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Testis-specific zinc finger protein topi
- LD06557p
- RT06796p1
- Wake-up-call, isoform A
- MIP29558p
- IP01149p
- Another transcription unit protein
- DNA-directed RNA polymerase II subunit RPB3
- Hyrax
- FI06213p
Sequence:
MSGNQDTLGQSQQVNESGDEYEEDAATSWTNELEQQESRTPADSPEFLDFVDSEDPLEDFERNPLQKEPLDLAVKPVSDINKKAAENHRRIYRQLGIHIPETPKSHPLLHYAFVVKLFLATDNSSIHYLKWSANGRELEVDYQGMQEHLSSGCSMFHCRNTLQFTGTLLAHGFERVSLKDVRKSSATNITLIYRNPNFVKGQLLKLHKLAQECEKIPEISSPGTAEPRRPPLHLPNYAHISRMVRRGDLCSTPYTSRSALQVARCHFQTLLGYQADLGVLKDRNNHDMFNKNIMTQLNVKRGRSSINNAPVDLAPSKVSFEKFVKPHESVINIGIGQAPDYAGYYGQVELFKVNEFFSEYLPRYGSKITGYKEIVMDATNKSIGFQQNLPIGMNYSDDEDDALPPISSDLDLDFMPSTSAAAKMKSTGRKVVEDSDLEQAMQELCGGSNLNEEEELPQTSTRFKAKPKPRAKTKAKPTKRQAKPVHSSSSECEDFKPDEVYEGFKSRNPKNVKLKPSDENISYTLEEGTDFEEQVIEETTETKVQDSQYDDLDDDDDDEEEDYFDEDDEDYVYKNLQYRNPPEPPKSRRYDLRNSKRNPR
Protein: Twinfilin (O94399)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. Prevents actin filament assembly by forming a 1:1 complex with actin monomers, and inhibits the nucleotide exchange reaction of actin monomers (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Actin
- F-actin-capping protein subunit beta
- Cofilin
- Adenylyl cyclase-associated protein
- Actin-depolymerizing factor gmf1
- Centractin
- Uncharacterized WD repeat-containing protein C9G1.05
- Coronin-like protein crn1
- Profilin
- Fimbrin
Sequence:
MSASVELKPTEKFSKFLEEYSSVPVRAAIISISNENSFDVKTMVEKSESIESDFKKVRECLLGSEEPAFVLVYDDSKKNLLQLISYVPENANVRRKMLYASSRAAFVRCVTLAKLDESYFASTPEELDYQQIMKSLSKQEDQSPLRQDELERKEYNESMQSSVTHKRPLVTRGVAMSIDDKALKALSDLKSSTENNLVILSIDKEVISLSQEKQNIPPSDVKSFFSSTEPNFAFYSLPKDGSSKILFIYICPMQATVKHRMVYSSSKLGLLDSIKAELGIVIDGKIESNDAADITEKEILHAAGISSPQAETSTTKTGFSRPRPPRRR
Protein: Small integral membrane protein 31 (Q3V2G4)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Leucine-rich repeat-containing protein 9
- Uncharacterized protein
- Transmembrame protein 274
- Uncharacterized protein C10orf143 homolog
Sequence:
MELPFTNLEVAFILLAFFIFSLFTLASIYTSPNERNEDDDFHLKEKRRKRKEFKGKKNCSDEEHKIETMQP
Protein: Myosin-IIIb (EC 2.7.11.1) (Q1EG27)
Organism: Mus musculus (Mouse)
Function: Probable actin-based motor with a protein kinase activity (By similarity). Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, stereocilium {ECO:0000269|PubMed:26754646}.
Interaction partners:
- Espin
- Espin-like protein
- Whirlin
- Twinfilin-2
- Epidermal growth factor receptor kinase substrate 8-like protein 2
- Epidermal growth factor receptor kinase substrate 8
- Unconventional myosin-XV
- Gelsolin
- Myosin-IIIa
- Peripheral plasma membrane protein CASK
Sequence:
MMLGLESLPDPMETWEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRCGKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFIKGTQGKVLCLQKQLAKVLQDQKHRNPVAKTRHERMHTGRPHRVEDAGKCCLEDDLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPHIFASADNAYQCLVTFSKDQCIVISGESGSGKTESAHLIVQHLTFLGKADNQTLRQKILQVNSLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEKNFHIFYYIYAGLYHQKKLAEFRLPEEKPPRYIAGETERVMQDITSKESYRTQFEAIQHCFKIIGFADKEVHSVYRILAGILNIGSIEFAAISSQHQTDKSEVPNPEALENAACVLCISSEELQEALTSHCVVTRGETIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNICSAEDRMNVGILDIFGFEDFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYKNEGVDAVLVQYEDNRPLLDMFLQKPLGLLALLDEESRFPQGTDQTLVDKFEDNLRCKFFWRPKGVELCFGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRAKITASSRSLPPHFSAGRAKVDTLEVIRHPEETTNMKRQTMASYFRYSLMDLLSKMVVGQPHFIRCIKPNDDRKALQFSQDRVLAQLRSTGILETVSIRRQGYSHRIFFEEFVKRYYYLAFRAHQTPPANKESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVMGRVVMLQAYTKGWLGARRYKRAKEKREKGAITIQSAWRGYDARRKLKQRSRRRSESEAHIHTVLQTTPDQKYCPDSGGESNRGHEETSRNCPAEADTDGHPQAQSPPTGCDVTSGHADTAAGYTVAELSVAGTDVSPSLVYHTASAHQRLSPCEDSLKPGSEEGLSQKQRAPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSQRKPRKLGQIKVLDGEDQYYKCLSPGACAPEETHSVHPFFFSSSPREDPFAQH
Protein: Exocyst complex component 2 (Exocyst complex component Sec5) (rSec5) (O54921)
Organism: Rattus norvegicus (Rat)
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular location: Midbody, Midbody ring {ECO:0000305|PubMed:18756269}. Note=Recruitment to the midbody does not require RALA, nor RALB. Colocalizes with CNTRL/centriolin at the midbody ring. {ECO:0000250|UniProtKB:Q96KP1}.
Interaction partners:
- Exocyst complex component 4
- Ras-related protein Ral-A
- Exocyst complex component 3
- Exocyst complex component 6
- Exocyst complex component 8
- Ras-related protein Ral-B
- Exocyst complex component 7
- Exocyst complex component 5
- Exocyst complex component 1
- Serine/threonine-protein kinase TBK1
Sequence:
MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGNPGPHSPMLDLDNDARPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPFSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIHCIMVTLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCISIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFGLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLETGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVIEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTPESRSSFKQALEALPQLASGADKKLLEELLNKFKSSMHLQLTCFQAASPTVMKT