wanglab/gogpt-training-data huggingface dataset:
Protein: Semaphorin-6C (Semaphorin-Y) (Sema Y) (Q9H3T2)
Organism: Homo sapiens (Human)
Function: Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Plexin-A1
- Plexin-A2
- Plexin-A4
- Plexin-A3
- Plexin-D1
Sequence:
MPRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDLPPASASRSVPIPLLLASVAAAFALGASVSGLLVSCACRRAHRRRGKDIETPGLPRPLSLRSLARLHGGGPEPPPPSKDGDAVQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKGAEPPAPLTSRALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRCASAPARPALSAPAPRLGVGGGRRLPFSGHRAPPALLTRVPSGGPSRYSGGPGKHLLYLGRPEGYRGRALKRVDVEKPQLSLKPPLVGPSSRQAVPNGGRFNF
Protein: Protocadherin-20 (Protocadherin-13) (Q8N6Y1)
Organism: Homo sapiens (Human)
Function: Potential calcium-dependent cell-adhesion protein.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MRGRGNARSSQALGVSWCPATWHPRLDMGRLHRPRSSTSYRNLPHLFLFFLFVGPFSCLGSYSRATELLYSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNSEGFHVKRVIKVQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEPTHRKVESVSCMPTLVALSVISLGSITLVTGMGIYICLRKGEKHPREDENLEVQIPLKGKIDLHMRERKPMDISNI
Protein: Heterogeneous nuclear ribonucleoprotein C (Heterogeneous nuclear ribonucleoproteins C1/C2) (Zgc:55701) (Q803J4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RNA-binding motif protein, X chromosome
- YTH domain containing 2.
- YTH domain-containing 1.
- YTH domain-containing family protein
- YTH domain-containing family protein 2
- Pre-mRNA-splicing regulator WTAP
- RNA demethylase ALKBH5
- N
- YTH N
- Interleukin enhancer-binding factor 2 homolog
Sequence:
MDRASSASQLIASNVTNKTDPRSLNSRVFIGNLNTMLVTKADVEAIFSKYGKIVGCSVHKGYAFVQFAQERNARTAVQGEDGRMVVGQVLDVNLAGEPKPHRSKTTKRSAGDMYSSSSSFELDYDFQRDYYDRMYSYPSRVPAPPPLSRAVIPSKRPRVSTSGATSRRTKSSFATSSKSSQRTSSRTLKADDLQTIKRELSQIKHKVDFLLESLDRMEKDHGKKSEGKSVKAEVGEVSPLQHSSKKEREREEQEINDSEEERDLLGEEEEEEEEEEVKSQGGENENEEEEGEEEEGEHEEGEDDGDSINGDDS
Protein: Protein phosphatase 2C homolog 1 (PP2C-1) (EC 3.1.3.16) (P40371)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: It has a serine and threonine phosphatase activity. Has a specialized role in the heat shock response. May be responsible for the dephosphorylation of hsp90. Also has a role in maintaining osmotic stability.
Interaction partners:
- Mitogen-activated protein kinase sty1
- Shk1 kinase-binding protein 5
- Tyrosine-protein phosphatase 1
- Protein phosphatase 2C homolog 3
- Mitogen-activated protein kinase spm1
- Tyrosine-protein phosphatase pmp1
- Tyrosine-protein phosphatase 2
- Protein kinase wis1
Sequence:
MKGSHPNAGSLLEPLHKLNPFSENSTSGHRKNASDHSADGETRPIAIEMKDSKGNTVPVGNSRPSKASNWLAGLMEDKNQRWRRSMEDTHICLYDFGGNQDDGFVAVYDGHAGIQASDYCQKNLHKVLLEKVRNEPDRLVTDLMDETFVEVNSKIAKATHNDICGCTAAVAFFRYEKNRTRRVLYTANAGDARIVLCRDGKAIRLSYDHKGSDANESRRVTQLGGLMVQNRINGVLAVTRALGDTYLKELVSAHPFTTETRIWNGHDEFFIIACDGLWDVVSDQEAVDFVRNFVSPREAAVRLVEFALKRLSTDNITCIVVNLTRNPGDLDDSGLTADNDSYSNDYY
Protein: Tissue factor (TF) (Coagulation factor III) (CD antigen CD142) (P20352)
Organism: Mus musculus (Mouse)
Function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Subcellular location: Membrane {ECO:0000250|UniProtKB:P13726}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P13726}.
Interaction partners:
- Coagulation factor VII
- Tissue factor pathway inhibitor
- Prothrombin
- Thrombomodulin
- Coagulation factor X
- Coagulation factor IX
- Vitamin K-dependent protein C
- Coagulation factor XI
- Antithrombin-III
- von Willebrand factor
Sequence:
MAILVRPRLLAALAPTFLGCLLLQVIAGAGIPEKAFNLTWISTDFKTILEWQPKPTNYTYTVQISDRSRNWKNKCFSTTDTECDLTDEIVKDVTWAYEAKVLSVPRRNSVHGDGDQLVIHGEEPPFTNAPKFLPYRDTNLGQPVIQQFEQDGRKLNVVVKDSLTLVRKNGTFLTLRQVFGKDLGYIITYRKGSSTGKKTNITNTNEFSIDVEEGVSYCFFVQAMIFSRKTNQNSPGSSTVCTEQWKSFLGETLIIVGAVVLLATIFIILLSISLCKRRKNRAGQKGKNTPSRLA
Protein: GH06635p (Q9W410)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Paired amphipathic helix protein Sin3a
- Chromatin assembly factor 1 p55 subunit
- Histone deacetylase HDAC1
- NuA4 complex subunit EAF3 homolog
- BRCA2-interacting transcriptional repressor EMSY
- EG:115C2.8 protein
- Lysine-specific demethylase 5
- FI07430p
- BRMS1 transcriptional repressor
- Sin3A-associated protein 130, isoform C
Sequence:
MSKLDQDPNASLSIMEQIKQLIRPPPNEDEKMMQRSTNTKHPYYRRPGRGHNHDYCDACEEGGNLLCCDRCPSSFHLQCHDPPLSEEDIPSGQWLCHSCRMSKLSQPPASSSKASSVERVPSAGSGSRANTPSSGDLESIPLKIRNLRKRSNSERNSTEKLLAKMPMSIQRALDPNKKPTPLDDVIRAATMMNPQQFSLPPELELHTQFPGNGKVQPVQQTHPPSGNGGNRRCAGNQRRNSKPFELDAQGLVPLPAKTCFYCTRSCKRAPLISCDYCPLYFHQDCLDPPLTALPAGLWMCPNHAENFIDANMTNSISATERVRLWNRFHQPLDHENVKLEFFRRVNTRNPPFRTKRNLRARAHIEVPAIVRYHYDHPPPLLPSMRQTLRYDRVKRRNNLPTEVEEISRESVTESLLKDLEALRTAHAKFREIQREFGTLETAIDGDSDSDPSPEEKRTETNTPADKVNGEVDTENPNTESNAQASEQPSVVKVESKTSLEVEASFEEDEEDSKKSTGIIDADLLHLDVDIIKKLAHQRLQQLVEEHPEIVTQYKNRTAARRLRQLASVDGTHVAGETAALQGQLAPEDMNRFSLLFTSETSSILAQKNGNAADEDPATALHPALATAAAIAAADAAAESYAPRARSDTEKAYELASRLELKLLQCKVQARAVITPLGDMLEDSRWFSSLGLDHSIFMRYRTLYIGYGGHYSPSTTLAQTETVDLSAIGYCCRISPQHAIIFYDEFSKSYELINYSEFGTEVNGQLYACDVTERMTTHAGKPMRPDDAELKKRVDEMLDKRRNINRQFETKKIDKERLAPIVKPACRCMNAGPVPMVDGAWEGSAVLAHGSLLRFGCLSFVFVVPSVDLLQAQARSKRS
Protein: Transketolase (EC 2.2.1.1) (Q6FWC3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Transaldolase
- Glucose-6-phosphate isomerase
- Transaldolase
- Fructose-bisphosphate aldolase
- Ribulose-phosphate 3-epimerase
- Ribose-5-phosphate isomerase
- Fructose-1,6-bisphosphatase
- Fructose-1,6-bisphosphatase
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Glyceraldehyde-3-phosphate dehydrogenase 1
Sequence:
MSFGEIDKLAVSTIRLLSVDQVSKANSGHPGAPLGMAPAAHVVWSQMRTNPKNPDWIARDRFVLSNGHACALLYSMLHLTGFDFSIDDLKNFRQLNSRCPGHPEFELPGVEVTTGPLGQGISNAVGMAIAQANFAATYNKPDFTLSDSYVYTFLGDGCLQEGVSSEACSLAGHLKLGNIIAIYDDNKITIDGNTTVSFDEDVCKRYEAYGWEVLHVENGNEDLNAIAQAVNKAKQSKDKPTLIKMTTTIGYGSLNAGSHSVHGSPLKEDDLKQLRKKFGFDPEKSFVVPQEVYDYYQAKIATPGAKANQEWDAKFAKYQQKYPEQGKELARRLAGELPAGWCSKLPTYTPADSAVATRKLSEIVFQSIYDELPEMIGGSADLTPSNLTRWKEAVDFQPPSSGLGDYSGRYIRYGIREHGMAAIMNGISAFGANYKAYGGTFLNFVSYAAGAVRLSALSGHPVIYVATHDSIGVGEDGPTHQPIETLAHFRALPNLHVWRPADGNETSAAYKVALESKHTPSVIALSRQNLPQLEGSSVEKALKGGYVLKEANNADITLVSTGSEVYLTVDAVKVLAAKGITARVVSLPDFLAFDQQPEDYKLSVLPDGAPVMSVEVLSTKSWGKYAHESFGIDRFGASGKAPEVYDYFGFTPEGIAERAEKVVKFYHGQKLSSPLKKAL
Protein: Putative D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) (DD-carboxypeptidase) (DD-CPase) (Penicillin binding protein 4B) (P77619)
Organism: Escherichia coli (strain K12)
Function: Penicillin-binding protein. Has low DD-carboxypeptidase activity.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01034, ECO:0000305|PubMed:16402224}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01034, ECO:0000305|PubMed:16402224}.
Interaction partners:
- D-alanyl-D-alanine carboxypeptidase DacA
- D-alanyl-D-alanine carboxypeptidase DacD
- D-alanyl-D-alanine carboxypeptidase DacC
- D-alanyl-D-alanine carboxypeptidase DacB
- N-acetylmuramic acid 6-phosphate etherase
- Beta-hexosaminidase
- N-acetylmuramoyl-L-alanine amidase AmiD
- PTS system N-acetylmuramic acid-specific EIIBC component
- Penicillin-binding protein 1B
- Penicillin-binding protein 1A
Sequence:
MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMDRWISQQVDVGYPSVNLLIIKDNQIVYRKAWGAAKKYDGSVLMEQPVKATTGTLYDLASNTKMYATNFALQKLMSEGKLHPDDRIAKYIPGFADSPNDTIKGKNTLRISDLLHHSGGFPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESVTGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTSTLWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFNAETVKMFTTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMTIVMLSNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQK
Protein: Retinoblastoma 1 (Q9YGE5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPPKKRNSGAAQNKEMKPSIKNASPDKENPDLSIEKHQEKDADFMTLCQSLQVIDAVCDRAWTIWKAVQASVDKVLDTQKKLWAACLFVAVIDLEIASFTFTQILKAVDLNVKQFLGLLKKMDVNLDTISTKVNSAVTRLEKKYDVSRALYQRFEKTCSKIYAEDSEAKGKEILRSCWTMFLLAKGRALQMEDELVISLHLMVCVLEFFIRRCPPSLLQPLYQSVISTAQSPPTRTSRRNQSKAKPRQAPPEVDVQLLETLCKENDCSVEEVKSVYQTSFSAFLDSMSLSGTRDLPQATDLSKQYEELYFKSRDFDSRLFLDNDETLLTPKVEPMPVERTPRKNMPEDVVLIPPQTPVRAAMNSIAQLRVDLITSGDQPSSNLAVYFKNCTVDPTEEVLQRVESLGLLFSQRFGQAVGPRCVGLGKQRFTLGIRLYYRVMESMLKSEEKRLSVQNFSKLLNDSTFHTSLLACALEVAMATYGGSTFKNGGYSNGGVPVETDLCFPWILDVFQLTAFDFYKVIESFIKAEPSLSKDIVKHLERCEHLIMETIAWREDSPLFELLKRTREEGPVEQAEPPATLNQPLQHNHTAADLYLSPVRPSSRTLPAPESTAPPSSQPSAPAPHQTPRHPKSNSLSLFYKKLYRLAYMRLKMLYTQLLTSHPELEPIMWTLFQHTLQNEYELMRDRHLDQLMMSAMYAICKVKNVDLRFKTIVTAYKNMPNTNQETFKHVLIREGQYDSIIVFYNLVFMQKLKTNILQYASPRPPTLSPIPHIPRSPYKFPNSPLRVPGSNNVYISPMKSPTRMSPVMTPRTRILVSIGESFGTSDKFQKINAMVNSSDRSLKRSLDMSSAPKPLKRLRFDVEGQDESDESKPGEESRLIQKLAEIGSTRTRMQEQKMKDDAESEKDKP
Protein: Lipin isoform J (Lipin, isoform J (EC 3.1.3.4)) (E5DK16)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKLGDSGEAFFVEECLEDEDEELPANLATSPIPNSFLASRDKANDTMEDISGVVTDKNASEELLLPLPLPRRNSIDFSKEEPKEAVVEGSKFENQVSDYTQRRHTDNTLERRNLSEKLKEFTTQKIRQEWAEHEELFQGEKKPADSDSLDNQSKASNEAETEKAIPAVIEDTEKEKDQIKPDVNLTTVTTSEATKEVSKSKTKKRRKKSQMKKNAQRKNSSSSSLGSAGGGDLPSAETPSLGVSNIDEGDAPISSATNNNNTSSSNDEQLSAPLVTARTGDDSPLSEIPHTPTSNPRLDLDIHFFSDTEITTPVGGGGAGSGRAAGGRPSTPIQSDSELETTMRDNRHVVTEESTASWKWGELPTPEQAKNEAMSAAQVQQSEHQSMLSNMFSFMKRANRLRKEKGVGEVGDIYLSDLDAGSMDPEMAALYFPSPLSKAASPPEEDGESGNGTSLPHSPSSLEEGQKSIDSDFDETKQQRDNNRYLDFVAMSMCGMSEQGAPPSDEEFDRHLVNYPDVCKSPSIFSSPNLVVRLNGKYYTWMAACPIVMTMITFQKPLTHDAIEQLMSQTVDGKCLPGDEKQEAVAQADNGGQTKRYWWSWRRSQDAAPNHLNNTHGMPLGKDEKDGDQAAVATQTSRPTSPDITDPTLSKSDSLVNAENTSALVDNLEELTMASNKSDEPKERYKKSLRLSSAAIKKLNLKEGMNEIEFSVTTAYQGTTRCKCYLFRWKHNDKVVISDIDGTITKSDVLGHILPMVGKDWAQLGVAQLFSKIEQNGYKLLYLSARAIGQSRVTREYLRSIRQGNVMLPDGPLLLNPTSLISAFHREVIEKKPEQFKIACLSDIRDLFPDKEPFYAGYGNRINDVWAYRAVGIPIMRIFTINTKGELKHELTQTFQSSYCSMTYIVDQLFPPVKLDEASAEFSNFNYWRDPIPDLEIPELETALVPPSTKVDMATLRPIPEK
Protein: Growth arrest-specific protein 2 (GAS-2) (O43903)
Organism: Homo sapiens (Human)
Function: May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:24706950}. Membrane {ECO:0000250|UniProtKB:P11862}; Peripheral membrane protein {ECO:0000250|UniProtKB:P11862}. Note=Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles (By similarity). Colocalizes with detyrosinated alpha-tubulin along the length of microtubule bundles in inner and outer pillar cells (By similarity). {ECO:0000250|UniProtKB:P11862}.
Interaction partners:
- Growth arrest-specific protein 1
- Leucine zipper protein 2
- Caspase-3
- Caspase-7
- Ras-like protein family member 10A
- Lipase member I
- Periplakin
Sequence:
MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFIRMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYLVVSASYKAKKEIK
Protein: LD21089p (Q95RL3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQVC
Protein: DNA-binding protein HU (Q72B43)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MTKADLVDKIAAKANLTKASAERSLNAFLDAVKDVLASEGKLTLTGFGTFAVESRQERKGRNPRTGAEIKIPASKVVKFRPGKTLKDAVK
Protein: MIP03875p (Narrow, isoform C) (C3KGN2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- IP10846p
Sequence:
MAKIVLFCLLSLLACAAGQRITTIHLDGVQYFISRMNPYSPELNYFLAYQYCRSLGLQLASFETKEKAESMTTYLKNAGYGNYDFWTSGNRLGTGMFLWMSTGLPFNATFDFFENSADAIQAGLLDPVDHNSNTSPQRTARDSSSGAEKGCVILKQPTLKWMPEDCSAVKDFICEQTRCYYYNYGSIPVSSAQGRPITSTTPRTPASLMNLHVAATTTPLPLLMSTSGAMYTAAKAKSSPAVGHRLIDDSSSQQQPSFMSFKLNHDRSLPDTDSTDVDVEDQEADLDGEEHDDHEAEGEEEHDEHDNFEEHARELSNDNDGDIKEHVFPLSDNELHPEVHSIEEVQQQLQQEDADADSAPAPAAAEDNESSQHDAEADGEHEQDGAEGETDLENETPVDLIKANEPLAMPSSTESPAAAIEERIKQIAQDFQKMASSQELQPKEELTPQSSLSLNDLIRTLRPNEQQIIPQIDSDYSNAMRVLGKPMAANN
Protein: GBF's pro-rich region-interacting factor 1 (F4IVF9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLALSPATRDGCDGASEFLDTSCGFTIINPEEEEEFPDFADHGDLLDIIDFDDIFGVAGDVLPDLEIDPEILSGDFSNHMNASSTITTTSDKTDSQGETTKGSSGKGEEVVSKRDDVAAETVTYDGDSDRKRKYSSSASSKNNRISNNEGKRKVKTRLNEQVYNGFVFFLKVDWTPELHRRFVEAVEQLGVDKAVPSRILELMGVHCLTRHNVASHLQKYRSHRKHLLAREAEAANWTRKRHIYGVDTGANLNGRTKNGWLAPAPTLGFPPPPPVAVAPPPVHHHHFRPLHVWGHPTVDQSIMPHVWPKHLPPPSTAMPNPPFWVSDSPYWHPMHNGTTPYLPTVATRFRAPPVAGIPHALPPHHTMYKPNLGFGGARPPVDLHPSKESVDAAIGDVLTRPWLPLPLGLNPPAVDGVMTELHRHGVSEVPPTASCA
Protein: Embryonic ectoderm development (A0A5F9ZI63)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGSHARPPRRLGAICDSGGGGGGGGGSGNFAASSGRACLTAVWRRPRPRRQEPGGRRRNMSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
Protein: ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (EC 7.6.2.-) (Q9JI39)
Organism: Mus musculus (Mouse)
Function: Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner. May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria. Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:10835348}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9NRK6}.
Interaction partners:
- Mitoferrin-1
- Ferrochelatase, mitochondrial
- Mitoferrin-2
- Transmembrane protein 14C
- Protoheme IX farnesyltransferase, mitochondrial
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
- Protoporphyrinogen oxidase
- Choline/ethanolamine transporter FLVCR1
Sequence:
MRAPSARALLLIPRRGPAVRAWAPAVSSRIWLASEWTPLVRAWTSLIHKPGSGLRFPAPLSGLPGGVGQWATSSGARRCWVLAGPRAAHPLFARLQGAAATGVRDLGNDSQRRPAATGRSEVWKLLGLVRPERGRLSAAVGFLAVSSVITMSAPFFLGRIIDVIYTNPSEGYGDSLTRLCAVLTCVFLCGAAANGIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGVGMMFFVSPSLATFVLSVVPPISVLAVIYGRYLRKLSKATQDSLAEATQLAEERIGNIRTIRAFGKEMTEVEKYTGRVDQLLQLAQKEALARAGFFGAAGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGLSIGGLSSFYSELMKGLGAGGRLWELLERQPRLPFNEGMVLDEKTFQGALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENIAYGADNLSSVTAQQVERAAEVANAAEFIRSFPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQEALDRLMEGRTVLIIAHRLSTIKNANFVAVLDHGKICEHGTHEELLLKPNGLYRKLMNKQSFLSYNGAEQFLEPARA
Protein: Tumor necrosis factor ligand superfamily member 13 (A proliferation-inducing ligand) (APRIL) (CD antigen CD256) (Q9D777)
Organism: Mus musculus (Mouse)
Function: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 13B
- Tumor necrosis factor receptor superfamily member 17
- Tumor necrosis factor receptor superfamily member 13C
- Tumor necrosis factor ligand superfamily member 12
- Acidic leucine-rich nuclear phosphoprotein 32 family member A
- Protein SET
- Nuclear pore complex protein Nup214
- Exportin-1
- Tumor necrosis factor ligand superfamily member 13B
Sequence:
MPASSPGHMGGSVREPALSVALWLSWGAVLGAVTCAVALLIQQTELQSLRREVSRLQRSGGPSQKQGERPWQSLWEQSPDVLEAWKDGAKSRRRRAVLTQKHKKKHSVLHLVPVNITSKADSDVTEVMWQPVLRRGRGLEAQGDIVRVWDTGIYLLYSQVLFHDVTFTMGQVVSREGQGRRETLFRCIRSMPSDPDRAYNSCYSAGVFHLHQGDIITVKIPRANAKLSLSPHGTFLGFVKL
Protein: Putative glycogen synthase kinase-3 homolog (GSK-3) (EC 2.7.11.26) (Protein gasket) (P83101)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Protein kinase shaggy
- Axin
- cAMP-dependent protein kinase catalytic subunit 2
- Segment polarity protein dishevelled
- Armadillo segment polarity protein
- cAMP-dependent protein kinase catalytic subunit 1
- LD23779p
- Kinesin-like protein costa
- TBC1 domain family member 7
- Gigas, isoform A
Sequence:
MASQSKNSGLTNKVTTVVATNAFGADVMSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLPELKPHPWSKVFRIRTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDPHQQLPNGRSLPPLFNFTDYEKTIEPDTMPLLLPRAQGSSTTKEPSAAHRNRNTAGEESPRKTEDSQKPATAALSKSPGPSGKALESPPGFLQHDLGNGDHVAVGTMPMEPLTLEQNHFAAESYAVGEDAEDNLEEDVGDENDYDYDDGGQCNSTYISDDMDEASESDDDDFEEEDEN
Protein: [histone H3]-lysine(36) N-trimethyltransferase (EC 2.1.1.359) (SET domain-containing protein 2) (D4A5H6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKSVPESLELDMKQDIVSNSLEEHTNQTLKEQADNALQKEDSHIGKEEEVSDGSKISLSSKKASSKKKSSQFEGTFLGSESDEDSVRTSSSQRSHDLKSSTSIEKERDFKKSSAPSKSEDLGKSSRSKTERDDKYFSYSKLERDTRYVSTRCRSERDRRRSRSRSRSDRVSRTSLSYSRSERSHYYDSERRYHRSSPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRTSAHSYRDLRTSSSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSEHEAIKRCCSPPNELGFRRGSSYSKHDNNSTSRYKSALSKSISKSDKFKNSFCCTELNEENKQSHSFSLQTPCSKGSELRTINKIPEREKTGSPSPSNQLNDSPTFKKLDESPILKPEFIGHDSHESIKELELPKMKNDQLRNFCSIELNVNGSPETETDVATFRTSKPDAISMTSDDSVTGSEVSPLIKGCVLSSNGFQSVGRCRERDADDACRQHNKSKSPFRETEPLLSPHHDKVMSLPVKTIDYSKTLIKEPVDKRHSCCKTKDSDRYCSPNESSEAENREISSNCFVNVHLDSKTVVCDNRELTDQHSEFTCDGYKQSIGSTSSASLNHFDDLYESVGSSGISSLQSLPSGIRCEENTSPALDTVQSKKGIDFLKYVGKETDVVSALPDSGKAFSSWENRHNMLSGQSLQESQEEGSSTLHERRGRSEVSLDEEEQRGHTHISDDSEVVFPYDLNLTMEDSDGVTYTLKCDSSGNAPEIVSTVHGDYSASSASSSDESDSEDTESDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDGLESRRHAYEEKFESMASKGCSQTEKFFLHKGTERNPETSYSQFSRKIDNHLPEIAHSQSDGVDSTSHTDVKSDSVGHLNSEDAIRAKMSRPQELPVYCDDFEDLPNTSRQQMIFSNRPDSSRLGKAELSFSSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSAEHYGGTHDYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREEEENWDQRSGSHFSSPSNKFFFHQKDKGSVQAPEISSNSIKDSLVINERKDFSKNFEKNDIKERGPPKKRRQELESDSESDGELQARKKVRVEIEQGQSSVPQHSELVGPSCAMDDFRDPQRWKEFAKLGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEVDTDTPKKLIFRRLKIISENSMDSAVSDVTSELECKDGKEDLDQLETVTVEEDEELQSQQLLPSQLCESKVESESTIDVSKLPISEPEADTETEPKDSNGTKLEETIAEETPSQDEEEGVSDVESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKESTVTERGRDTAAFRDQTAPKTPNRSREREPDKQSQNKEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPFDSLGYNASHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTESLAAPPSVPVVPHGAASVEVSSSQYAAQSESVVHQDSSVPGMPVQTPGPVQGQNYSVWDSNQQSVSVQPQYSPAQSQATIYYQGQTCSTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPPEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKTSKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE
Protein: Uncharacterized protein YggT (P64564)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Pyridoxal phosphate homeostasis protein
- UPF0235 protein YggU
- dITP/XTP pyrophosphatase
- Heme chaperone HemW
Sequence:
MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVTQPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTIGLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVLLLYVINMGVAEVLQATGNMLLPGLWMAL