wanglab/gogpt-training-data huggingface dataset:
Protein: Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase) (B7GTK2)
Organism: Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Function: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00318}. Secreted {ECO:0000255|HAMAP-Rule:MF_00318}. Cell surface {ECO:0000255|HAMAP-Rule:MF_00318}. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. {ECO:0000255|HAMAP-Rule:MF_00318}.
Interaction partners:
Sequence:
MAVIESVYARQILDSRGNPTVEVYLETEDGAQGKGLVPSGASTGEAEAWERRDGDKSVYGGKGVLNAVKAVNEVIAPKVIGMDAADQRALDDLMIELDGTPNKGKLGANAILGVSLAALYASAESAGLPLYRYIGGTNGHILPVPNMNIMNGGAHADFATDIQEYMISPYGFDTYSEALRAGVEVYHTLKNVLKKEGLNTGLGDEGGFAPKMKSNEDSLKYIMDAISAAGYEPGKQIGICLDVASSEFYNKETGKYRFDGEERDSAYMLDYYENLINEYPIVSIEDPFNEEGWEDWAAITARLGDRLQFVGDDLLVTNPARLQKAIDLGAANSLLVKLNQIGSVTETLDAIELATANGYTSMVSHRSGETPDTTISDLAVAKNTRQIKTGAPARGERVAKYNRLLEIEEELGSTAQYAGYTAFKACKKYLAK
Protein: Zinc finger protein pita (Protein spotted-dick) (Q95RQ8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000269|PubMed:25342723}. Chromosome {ECO:0000269|PubMed:25342723}. Note=On polytene chromosomes of third-instar larvae colocalizes with Cp190. {ECO:0000269|PubMed:25342723}.
Interaction partners:
Sequence:
MAAKLEVREAMLTEKRVCRFCLTEQKLASIFEENPRVKTTANLPLQIMAITAIEVYAGDGMPGHICLECRLLFEHCYRFKQMCKRAETLLRQYPLTGNWPSPLEKPRAPMTMVASKKLLVVPAKTAEPSETPKKLLNTMAKSSSQVIIEDVQVLESAMVTPRTVAGSSPVPRRSHAYELKVDNNQELSMDDVQSMLEDMASELEKEFPDIPQKASPVKPKVLNKSSIRILNKGPAAPVEPRLATPKVKRDDSGNVAIVTEVLDSDLPLDDQDDPTKNAEKVATDVFPCPDCERSFPLQQLLEIHRLNHTRSRSFQCLLCEKSFFSKYDLAKHNFVHTGERPFKCAICSKAFTRKALLHRHERTHTDVPKFICVYCEKPFLSRQEMEKHAERHQKKRPFQCGVCTKSFAFKQGLERHETVHSTNLPFPCQHCERSFSTASKLARHLVAHAGKRAYPCKYCHKSYMLSHHLSRHLRTHTQTSDASFVCSECKVSYSNYNDLLDHALIHATASLKCPMCRKQIEDIDSVESHMDQHKQSERHACEFCDHIFLTQKCLQRHIEDDHVVEMEPYQNEFEDDGEGEGGVDEKEEHLDDFEDMDNVKQEEFVTEYLEDDALYEDHLDDSDESFTPPPPKQRKTNPPKDAQQSVRQTRSRDAQRITQKTGKNEGKPHHKLERNLKNRRSAK
Protein: Small ribosomal subunit protein uS4c (30S ribosomal protein S4, chloroplastic) (P0C487)
Organism: Oryza sativa subsp. indica (Rice)
Function: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS2c
- Small ribosomal subunit protein uS7cz/uS7cy
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS11c
- 40S ribosomal protein S30
- Small ribosomal subunit protein uS8c
- 30S ribosomal protein S13
- 40S ribosomal protein S15
- Small ribosomal subunit protein uS12cz/uS12cy
Sequence:
MSRYRGPRFKKIRRLGALPGLTRKTPKSGSNLKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKSSTGQVLLQLLEMRLDNILFRLGMASTIPEARQLVNHRHILVNGRIVDIPSFRCKPRDIITTKDNQRSKRLVQNSIASSDPGKLPKHLTIDTLQYKGLVKKILDRKWVGLKINELLVVEYYSRQT
Protein: Histone RNA hairpin-binding protein RNA-binding domain-containing protein (Q57WX0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Small nuclear ribonucleoprotein SmD1
Sequence:
MQTPLRPTIFPEGIEGSQTADSSIKVACGRDSSGRASGSPPDRERRLHQREKQLSFGYATEGYNNMIKLVEHDPLLKSGGIIPLSPPDVNKGSKRVWDVSLRKWRRALHMFDCVFIEGEDENKKTLESVIEDQRLQWVSTAYSGRRKEDRVKVSASTITNAQNSPHVCKKLHVEECLKVILREESCYEPVGNVVPVSASSLLKGADISPADAGIKIFVAPSPQNQCKQTPVRSGAVCSRVAPRCLNFDSSTPMQSKVPLNGVQEVKHLQSCVPPQPKENKNIWVTPTMWVDDGARTSPFTSIYQPPVLEQVSEVQQTPLNWNLFIPPQTYVCTPQPATAPGIVFDKFTPNTAPRRLTILRDSNTKSRGGEVDVLKRNLFPNSVMSPSHTDSLEKVFHPNTPLTRSCVRGEVPEIEANKPTGADCAQQILFTE
Protein: Cyclin-dependent kinases regulatory subunit (P13) (P08463)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Binds to the catalytic subunit of the cyclin dependent kinase (cdc2) and is essential for its biological function.
Interaction partners:
- Cyclin-dependent kinase 1
- G2/mitotic-specific cyclin cdc13
- Serine/threonine-protein kinase csk1
- Serine/threonine-protein kinase pef1
- Suppressor of kinetochore protein 1
- Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28
- G2/mitotic-specific cyclin cig1
- Mitosis inhibitor protein kinase wee1
- Meiosis-specific cyclin rem1
- G2/mitotic-specific cyclin cig2
Sequence:
MSKSGVPRLLTASERERLEPFIDQIHYSPRYADDEYEYRHVMLPKAMLKAIPTDYFNPETGTLRILQEEEWRGLGITQSLGWEMYEVHVPEPHILLFKREKDYQMKFSQQRGG
Protein: Neuronal migration protein doublecortin (Doublin) (Lissencephalin-X) (Lis-X) (O43602)
Organism: Homo sapiens (Human)
Function: Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
Subcellular location: Cytoplasm {ECO:0000305}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q9ESI7}. Note=Localizes at neurite tips. {ECO:0000250|UniProtKB:Q9ESI7}.
Interaction partners:
- Tubulin beta-2B chain
- Tubulin alpha-1B chain
- Calcium/calmodulin-dependent protein kinase type IV
- Serine/threonine-protein kinase H2
- Neurabin-2
- Calcium/calmodulin-dependent protein kinase type 1D
- RNA binding protein fox-1 homolog 3
- Serine/threonine-protein kinase DCLK1
- Calcium/calmodulin-dependent protein kinase type 1B
- Neurofascin
Sequence:
MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM
Protein: Alkaline-phosphatase-like family protein (Nucleotide pyrophosphatase-like protein (EC 3.6.1.9)) (Q9SU83)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alpha-glucan phosphorylase 1
- Alpha-glucan phosphorylase 2, cytosolic
- NAD
- NAD kinase 2, chloroplastic
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
- UTP--glucose-1-phosphate uridylyltransferase 2
- Nucleoside diphosphate kinase 1
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase II, chloroplastic
- Nudix hydrolase 19, chloroplastic
Sequence:
MISGDTLSAKKPKSVPQEEDQDPPSQSIALLDNHTDSSGSDSSTRSISSCFIFTSLLLVTCIALSAASAFAFLFFSSQKPVLSLNQISKSPAFDRSVARPLKKLDKPVVLLISSDGFRFGYQFKTKLPSIHRLIANGTEAETGLIPVFPTLTFPNHYSIVTGLYPAYHGIINNHFVDPETGNVFTMASHEPEWWLGEPLWETVVNQGLKAATYFWPGSEVHKGSWNCPQGLCQNYNGSVPFDDRVDTILSYFDLPSNEIPSFMTLYFEDPDHQGHQVGPDDPQITEAVVNIDRLIGRLIDGLEKRGIFEDVTMIMVGDHGMVGTCDKKLVVLDDLAPWIKIPSSWVQYYTPLLAIQPPSGHDAADIVAKINEGLSSGKVENGKYLKVYLKEDLPSRLHYVDSDRIPPIIGLVDEGFKVEQKKSKAKECGGAHGYDNAFFSMRTIFIGHGPMFSKGRKVPSFENVQIYNVISSILGLKAAPNNGSDEFSSSILLPRV
Protein: Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Inactive dihydropyrimidinase) (Unc-33-like phosphoprotein 3) (ULIP-3) (Q14194)
Organism: Homo sapiens (Human)
Function: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11562390}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11562390}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11562390}. Cell projection, growth cone {ECO:0000250|UniProtKB:P97427}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P97427}. Perikaryon {ECO:0000250|UniProtKB:P97427}. Note=Associated with centrosomes and the mitotic spindle during metaphase (PubMed:11562390). Colocalizes with FLNA and tubulin in the central region of DRG neuron growth cone (By similarity). Following SEMA3A stimulation of DRG neurons, colocalizes with F-actin (By similarity). {ECO:0000250|UniProtKB:P97427, ECO:0000269|PubMed:11562390}.
Interaction partners:
- Dihydropyrimidinase-related protein 3
- Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
- Dihydropyrimidinase-related protein 2
- Semaphorin-3A
- Plexin-A1
- Dihydroorotate dehydrogenase
- Dihydropyrimidine dehydrogenase [NADP
- Plexin-A4
- Uridine 5'-monophosphate synthase
- Cyclin-dependent kinase 5
Sequence:
MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG
Protein: Wnt inhibitory factor 1 (WIF-1) (Q9Y5W5)
Organism: Homo sapiens (Human)
Function: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
Subcellular location: Secreted.
Interaction partners:
- Protein Wnt-3a
- Protein Wnt-7a
- Protein Wnt-5a
- Protein Wnt-4
- Proto-oncogene Wnt-1
- Protein Wnt-11
- Protein Wnt-2
- Protein Wnt-10b
- Protein Wnt-16
- Protein Wnt-6
Sequence:
MARRSAFPAAALWLWSILLCLLALRAEAGPPQEESLYLWIDAHQARVLIGFEEDILIVSEGKMAPFTHDFRKAQQRMPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVNVPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYEASLIHALRPAGAQLRQHTPSLKKAEERRDPPESNYIW
Protein: Grunge, isoform H (Q9VSK5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAASTQGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERELEESRWSPGVVADGDLLMFLRAARSMAAFQGMCDGGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVKCPVSKGIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQSALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASRSSPAVSKEENSSLTEDDASECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNNTAGNGGGNATSISSGSTGGGAAGGNSSSKDQSANAVANGKRPKRGSETPDVSGGASVDSPKTPTKAVAESSANKRKGGKQDTPNKKKRTEQESNEPSAHEENAIKEKRKRPDSPVESMNSDSRPDSVLDDGESNTTDTTTAEQQSTKDSKETVSCKEEREMVTNDLEAKAEEKAIKAEALAEDSKDSAIKNMDEETNIQAPSSADTSLVDGPNPNALPSPVAAPITMKVPTIATVEALNASVDRKEAIEKMESCDSDPEMLKKLATIKQEVSPQQQQHMQQQSQQQMQQQLAPVGIPQPPSCPPSESVYIKKEPMEDSMDATCNQNSNEPQDLKVKIEIKNEDALKHSAGGLPPSGPCAPPSALHPLSGAPVESGQEPLHLQHMPHGQVTTQPPPGYLIDGQLKYGPSGQGVPPQPPQLHSDAAGGVSGAPPGAPTTPQKYPPEMEMKFAPQDLKYPPPPPLDALKYSQEMQAAAAAAAAAGKYDMKYMMEQQGKYNVELSAAHQPPSKPGYQDSLKIPDIKPGFGHLPHNVGSPLDAAHKYGPPPTSQESQQQQPQPPAHQVPPGATPPPGIAMPKPHYQHDVQTPPLGRPFEPTGLMLKYGDPLAAKYGPPQDLKYPMPPVSQAGPADVKPYGGENLIKSSPYGPPPESPIDASARSTPGQDSQGSNSNSQPPSMPPQPQQFQSPHPSPHMPSPAGGGLPPGMHPQNLIHGPPPGAAGGSGPQPPPPPTSLHQPTPTSAGPPSLQHGLHPGHQHSQLSVASSIPPSSIGIPPTLSTMAPSHMHPHLHPHAHLQGLHRPHDLPPSMHPHAPMPLSLQGHPQHGHGLPPSHTSQQQQQQQQQQQPGGPAGTVRTPSPAQQPPRSMHDPQSSREPPTSQPSTTMAGSSGPGGPPPQQSPHAHRTSPLPGLAGSGPPPPGLIGHPMAIHPHLAHLPPGHPAHAALAHPGHHLLSHSIAGLGPGGGPIALLAGPGGLGGIPESALSRRTPPSHLPHSHASSAPLTAHSVASMTSTSMSLTTSTVPSSAFSRASPSVQISSSGGGPSGPGSVGPGGMPNSSAAAAAAAAAHRAASPASSVSSLSRQSPLHPVPQSPLSHHPSSSALSAAAAAVAERDRHALMRQQSPHMTPPPVSNASLMASPLSKMYAPQPGQRGLGTSPPPHLRPGASPPVIRHPQMPLPLPLIAPGGGIPQIGVHPGQSPYPHPLLHPSVFYSPHHHPFNSPYGYAPYGPGFPAYMKPPPQPGQLDPAAVMAAHHAGLQGPPPQQMRQDEQNAAAAAAQAAAEKQHQAAAAAAAQQHKAPQQQQPGGMPPNKPPTPKTPQGPGGGMPPGMGGPGTPTGLPPGAYPGSHMPGYPQGPPHGSPFAPQDGQPHGLKPTSHMDALRAHAHSANSAGMGGGHHPTEPLPIDIEPDPEPEIPSPTHNIPRGPSPEAKPDDTECHRSQSAIFVRHIDRGDYNSCTRTDLIFKPVADSKLARKREERDRKLAEKERERRQQQQQQQQQQQQQQAAAAQQAAQQAKMKAELKPPYADTPALRQLSEYARPHVAFSPVEQMVPYHHPMGPMYRERELEEIKNAQAAAASQSRLDPHWMEYYRRGIHPSQFPLYANPAISQMERERLGIPPPHHVGLDPGEHMVRMPQPPEAGFQLPPNVGQYPRPNMLIPREPHSDVLLRMSYADQLQAAEFQRQSLHDQYFRQRPR
Protein: Cytoplasmic linker associated protein 2 (H7C4I5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XKKMGADLLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKTVKPALRDQLHSFWSSKVKVAILKYIETLAKQMDPGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFDYDT
Protein: PPE family protein PPE2 (P9WI47)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Inhibits nitric oxide (NO) production in activated macrophages. Acts by inhibiting expression of the host inducible nitric oxide synthase (iNOS). PPE2 is translocated into the host macrophage nucleus, where it interacts with a GATA-binding site overlapping with the TATA box of NOS2 (iNOS) promoter, and strongly inhibits NOS2 gene transcription. Reduction in NO production in turn facilitates intracellular survival of the bacilli inside the macrophage. In addition, disrupts the assembly of NADPH oxidase complex, which inhibits NADPH oxidase-mediated reactive oxygen species (ROS) generation in macrophages and favors M.tuberculosis survival. Acts by interacting with NCF2, the cytosolic subunit of NADPH oxidase, and preventing translocation of NCF2 and NCF1 to the membrane, which causes a reduction of the functional assembly of NADPH oxidase complex and a decrease in NADPH oxidase activity.
Subcellular location: Secreted {ECO:0000269|PubMed:23448669}. Host cytoplasm {ECO:0000269|PubMed:28071726, ECO:0000305|PubMed:23448669}. Host nucleus {ECO:0000269|PubMed:28071726}. Note=Translocated into the macrophage nucleus via the classical importin alpha/beta pathway. {ECO:0000269|PubMed:28071726}.
Interaction partners:
- Cobyric acid synthase
- Adenosylcobinamide kinase
- PE family immunomodulator PE15
- Exported repetitive protein
- ESX-3 secretion system protein EccD3
- L-lysine N6-monooxygenase MbtG
- Hypothetical alanine and valine rich protein
- Uncharacterized protein Rv0479c
- Tat
- Probable conserved transmembrane protein rich in alanine and arginine and proline
Sequence:
MTAPIWMASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAETADELAALLAAVQAGTWDGPTAAVYVAAHTPYLAWLVQASANSAAMATRQETAATAYGTALAAMPTLAELGANHALHGVLMATNFFGINTIPIALNESDYARMWIQAATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAASDEPNQVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPFLQAMFSGFDPWLPSLGNPLTFLSPANIAFALGYPMDIGSYVAFLSQTFAFIGADLAAAFASGNPATIAFTLMFTTVEAIGTIITDTIALVKTLLEQTLALLPAALPLLAAPLAPLTLAPASAAGGFAGLSGLAGLVGIPPSAPPVIPPVAAIAPSIPTPTPTPAPAPAPTAVTAPTPPPGPPPPPVTAPPPVTGAGIQSFGYLVGDLNSAAQARKAVGTGVRKKTPEPDSAEAPAAAAAPEEQVQPQRRRRPKIKQLGRGYEYLDLDPETGHDPTGSPQGAGTLGFAGTTHKASPGQVAGLITLPNDAFGGSPRTPMMPGTWDTDSATRVE
Protein: Paired box pox-neuro protein (Paired box neuronal protein) (P23758)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcriptional regulator that specifies poly-innervated organs (chemosensory bristle). Also controls the number of neurons.
Subcellular location: Nucleus.
Interaction partners:
- AT27166p
- Homeobox protein goosecoid
- ETS-like protein pointed
Sequence:
MPHTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSIRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNSGLWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVAPPTPAATPSIARYAKPPALMMNSAGEMPIKPAPKMPPSMGHGHSHGLNPNVSGLDLSYSALHKHWLWNPSLLYYTQAHIQAQAAASGGQFLPYAGGYLPHAMAAAAASSTSALGGFTKSESSIDLSTPGAAGDALSDCDSGKSSPAALSLTASGGGNGAGSAPEASPGSTLSHSRKRNPYSIEELLKKPEKRLRLDSNRLECLESSSCESSQDSPVAPPLETPEDEDPAEAEEEQEEEDSVEVVN
Protein: Synaptic plasticity regulator PANTS (Plasticity-associated neural transcript short) (Q6P5X5)
Organism: Homo sapiens (Human)
Subcellular location: Synapse {ECO:0000250|UniProtKB:Q3U595}. Synaptic cleft {ECO:0000250|UniProtKB:Q3U595}. Note=Detected in both the presynaptic and postsynaptic regions of the synapse and is secreted from neurons into the synaptic cleft. May be released by neuronal dense core vesicles which mediate the release of cleaved neuropeptides. {ECO:0000250|UniProtKB:Q3U595}.
Interaction partners:
Sequence:
MADGSGWQPPRPCEAYRAEWKLCRSARHFLHHYYVHGERPACEQWQRDLASCRDWEERRNAEAQQSLCESERARVRAARKHILVWAPRQSPPPDWHLPLPQEKDE
Protein: Probable Na(+)/H(+) antiporter C3A11.09 (O14123)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Sodium export from cell, takes up external protons in exchange for internal sodium ions.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAWSQVEISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATATGLIFGPYVAKLFVPTSWGNTDYITEELARVLLVVEVFAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSTGFMYALIPRLSFLESLAIAACITATDPVLASSIVGKGKFARRVPGHLRNMLLAESGCNDGMAIPFLYLAIYLIIEKPARHAGRDWVCIIILYECTFGCVLGAIIGVIARKMIKFSERRGLMDRESFLVFYFVLALFCGGIGTIIGVDDLLVSFCAGAAFSWDSWFSKKTEESHVSNVIDLLLNLSFFVYVGAIMPWPQFHMPHMDLSVWRLVVLAICILIARRIPAVLLFKSFVPDIINWREALFAGHFGPIGVGALYTCLVARAELEVHSTVPEPNDAIENPEIPNWYCIQVMWPVVCFLVLSSIIVHGSSIAFFMLGKRINTLALSFTRTRDSHFAFNLPRVRQGQSLPIKRVDALRSSANSIASSIRRRHPVNIQEDEDADISTVSLPEAAHLREERAESPRGGHYDAEEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSESEDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTRAWE
Protein: Large ribosomal subunit protein mL49 (39S ribosomal protein L49, mitochondrial) (L49mt) (MRP-L49) (Q9CQ40)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q13405}.
Interaction partners:
- Large ribosomal subunit protein bL19m
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein mL43
- 39S ribosomal protein L40
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein bL36m
- Large ribosomal subunit protein uL30m
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein uL4m
Sequence:
MAAAVLRAALQDWRSCLGRSYGRRKLSQTQGPPDNPGFVESVDEYQFVERLLPPTKIPEPPKHKHYPTPSGWQPPRDPLPSLPYFVRRSRMHNIPVYKEITHGNRQMTLIRKVEGDIWALQKDVEEFLSPLLGKTPITQVNEVTGTLRIKGYFDEQLKAWLLEKGF
Protein: Probable D-xylose 1-dehydrogenase (NADP(+)) (XDH) (EC 1.1.1.179) (D-xylose-NADP dehydrogenase) (Dimeric dihydrodiol dehydrogenase homolog) (NADP(+)-dependent D-xylose dehydrogenase) (Q9UT60)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: NADP-dependent D-xylose dehydrogenase catalyzing the oxydation of D-xylose into D-xylonolactone (By similarity). May also display activity with other sugars. May play a role in the regeneration of NADP(+) in the presence of these sugars (Probable).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Galactokinase
Sequence:
MTSMSGASPVIHWGFLGAGSIAAVFAKDLVGVPERHKVQHEIVAVATRDSEHRASSFAKNHCAPCKPKAYGSYEELVKDDKVDIVYISSTHPQHYEVVKLALLNDKAVLCEKPLTINYPEALELVELARARNLFFAEGFWIRFYPIVKAAKTLLHEDRVCGDHFRLFVDFSQDFRFRELPSESRLRTVSLGAGVLLDMGVYPLTWSRLLLYDDPKNEKQEPTVSSNALTFEDHNGDIGDYTTAVTLVFPKTESIAMLCTSMDRGKMSDDFLKLDGENGNQLFISGDCYRPQSIKLIRASGETEVFDFSFDDATGFFYEQDAVAECLLKNMKEAPEIPHEETLKMMQLTDQIRRQINVTYPADLRYTTA
Protein: Mitochondrial import inner membrane translocase subunit TIM50 (Q38BI2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU365079}; Single-pass membrane protein {ECO:0000256|RuleBase:RU365079}.
Interaction partners:
Sequence:
MSTVPRQRIRGASFKQEYQCAALRRTRQRAPSMNQEMNSRWVLPDQDPRYNGKLTLALDLDETLVYAREGPLYARPGLDEFFQLCKEKCVEVVVWTAGLRAYAQAIIRNIDKDRVVSHCIYRHSKWFTGCAGYQKDLAVLGRPLEMVLIIENTPDCIRGHQQNGILVEDYEGGESADNTIHALQELVRRLCDSGMTVPQFISSCDMLKHGPIQTDVGDFIDVYRLDTSVWKPGEHVRVNRDLASLQC
Protein: Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (O74407)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glutamyl-tRNA
- Putative proline--tRNA ligase C19C7.06
- Probable methionine--tRNA ligase, cytoplasmic
- Aspartate--tRNA ligase, mitochondrial
- Probable glutamate--tRNA ligase, cytoplasmic
- Probable glutamine--tRNA ligase
- Isoleucine--tRNA ligase, cytoplasmic
- Putative leucine--tRNA ligase, cytoplasmic
- tRNA-aminoacylation cofactor arc1
- Target of rapamycin complex 1 subunit mip1
Sequence:
MSEMEKQVENLSLEAKNEKPKEVILGEDGKPLSKKALKKLEKEREKEQKRKEREAREAEEKKKREANEIDYSAGKYGDLPLNRSTARPGRTYTQISDISAKNDGQTVLLRARVYTSRLQGNKMCFFSLRQKYDTIQALAVVNKDTISKQMVKWCGSISLESIVLVEGIVKKSPEIIKSATVQDAEIHISSIYVISPIKKNLPFLVEDAGRSEEQIRESEENAAEGDSKFVRVNLDTRLDNRVLDLRTPTNQAIFDIQAGICQAFREFLLSNSFNEIHTPKMSGASSEGGSNVFKIQYFKTDGFLSQSPQLYKQMLIAADRERVFEIGPVFRAEDSNTYRHMTEFTGLDLEMAFNEHYHEVMEFIEKLFLYIFKTIREKYAKQVAVVRQQYPSEDFILPDADRIRFHFKDAVKLLKEAGYRKQLVPGQKVPEDEEFHYCEDPEFDDFSTPEERALGQIVREKYHTDFYVIDKYPSSVRPFYTMPDPEDPRYSNSYDFFMKGQEIMSGAQRIHDPELLVERMKALGVSPDVGLQQYIDAFAIGCPPHAGGGIGLERVVMFYLNLPNIRLASSFPRDPKRLLP
Protein: U8 snoRNA-decapping enzyme (EC 3.6.1.62) (EC 3.6.1.64) (IDP phosphatase) (Inosine diphosphate phosphatase) (Nucleoside diphosphate-linked moiety X motif 16) (m7GpppN-mRNA hydrolase) (B4DLR9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
MARARRLELAEALALGPGWRHACYALLHAPDPGILFGRLPLRYAILMQMRFDGRLGFPGGFVDSQDSSLEDGLNRGLLELLGEAAAAFRVERPDYRSSHAGSRPRVVAHFYAKSLTLEQLLAVEASATGAKDHGLEVLGLVRVPLYPA
Protein: Nuclear fallout (O61495)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Midbody {ECO:0000256|ARBA:ARBA00004214}. Recycling endosome membrane {ECO:0000256|ARBA:ARBA00004654}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004654}.
Interaction partners:
Sequence:
MAPMPRIQLPNGNSSIKASTNDFLFAETMSGDSSPTPSSPPSSTAGVAKSQCSSLSDGESFEGYGENEYPTQLREARSSNSNGSHNMSNHINNNPNISVGNNSGHNHSGHSNDGNNNLNGSTGVELDLAPHVGSSTPQDDDELNIMPRDNWARRSLRRTPTSSGRRQISSNALASQLYRSSSFNSSGRSSNCDTTEDMYSDISLENRHDYDYRLELLQRKVDDLSDTQNIAEDRTTRTKTEYAVLQARYHMLEEQYRESELRAEERLAEEQKRHREILARVEREASLQNENCQMKIRATEIEATALREEAARLRVLCDKQANDLHRTEEQLELARDQIGVLQQEHEEQAQALRRHEQEKKSTEELMLELGRELQRAREESGARAMPTTSPESIRLEELHQELEEMRQKNRTLEEQNEELQATMLTNQATMLTNGVEQGRHLLNGTLNSLAQELEEMSQAQLQQAFQEKEDENVRLKHYIDTILLNIVENYPQLLEVKPMERK
Protein: Glucans biosynthesis protein G (P33136)
Organism: Escherichia coli (strain K12)
Function: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
Subcellular location: Periplasm.
Interaction partners:
- Glucans biosynthesis glucosyltransferase H
- Glucans biosynthesis protein C
Sequence:
MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYETPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
Protein: ZM domain-containing protein (Q966J6)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSYSTYLPNNYHNDTKICINGVELLNRHEISSTQDRELQRFIDNNAHIIQYQERELPPPPPPRKTPSHKYEEMRRSLSRGPSSTLERYSSMDKLLGSQNREKNVEIEQGINPRDLPVCPNIDGHNYTAEFPGLEYLSDNKFIENLIKAGQVSIGNTGMISQPGSRVGSAMSAPYSQNQSANSTLTRQSHSQSHTLPHQMPQYQQYHRHATPPAPAPQHQNNTNYYTENTTSTTSYHPTSVTYGSSNANSQYGGSQSQYGSMSNVGTGSTYGTLKGGMKHTSTLPPTSPYSSLKRKGVSWLDQERARSLSPGLHQSTSTSRHVHQQYNRPASTIHTTTYTTTY