wanglab/gogpt-training-data huggingface dataset:
Protein: Ribosomal protein L26 (ATPase H+ transporting V0 subunit e1) (Rpl26 protein) (Q7SXA1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Ubiquitin-ribosomal protein eL40 fusion protein
- 40S ribosomal protein S12
- Large ribosomal subunit protein eL20
- Small ribosomal subunit protein uS9
- Large ribosomal subunit protein eL22
- Ribosomal protein L15
- Small ribosomal subunit protein eS28
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein eL24
Sequence:
MKLNTFVTSSRRKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQDIKEKGKYKEETIEKMQE
Protein: Cyclin-dependent kinases regulatory subunit (Q9VHN1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cyclin-dependent kinase 1
- S-phase kinase-associated protein 2
- Cyclin-dependent kinase 2
- G2/mitotic-specific cyclin-B3
- G2/mitotic-specific cyclin-B
- G2/mitotic-specific cyclin-A
- cyclin-dependent kinase
- Cell division cycle protein 20 homolog
Sequence:
MPADQIQYSEKYFDDNFEYRHVILPPDLAKHVPKAHLMTETEWRNLGVQQSPGWVHYMVHAPEPHVILFRRKRIPAEDAPQVAAANAAQAIANLCG
Protein: Calcium-activated chloride channel regulator 4A (EC 3.4.-.-) (Calcium-activated chloride channel regulator 6) (mClca6) [Cleaved into: Calcium-activated chloride channel regulator 4A, 110 kDa form; Calcium-activated chloride channel regulator 4A, 30 kDa form] (Q6Q473)
Organism: Mus musculus (Mouse)
Function: May be involved in mediating calcium-activated chloride conductance.
Subcellular location: Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted. Note=The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus. Associated with the microvilli of non-goblet cell enterocytes in the small and large intestine. Colocalizes with CFTR.
Interaction partners:
Sequence:
MAFSRGPVFLLLLLYLLWGSDTSLIRLNENGYEDIIIAIDPAVPEDTTIIEHIKGMVTKASTYLFEATEKRFFFKNVSILIPESWKDSPQYRRPKQESYKHADIKVAPPTVEGRDEPYTRQFTQCEEKAEYIHFTPDFVLGRKQDEYGDSGKVLVHEWAHLRWGVFDEYNEDQPFYSASSKKIEATRCSTGITGTNRVYACQGGSCAMRRCRTNSTTKLYEKDCQFFPDKVQSEKASIMFMQSIDSVTEFCKKENHNREAPTLHNKKCNYRSTWEVISTSEDFNSSTPMETSPSPPFFSLLRISERIMCLVLDVSGSMTSYDRLNRMNQAAKYFLSQIIENRSWVGMVHFSSQATIVHELIQINSDIERNQLLQTLPTSANGGTSICSGIKAAFQVFKNGEYQTDGTEILLLSDGEDSTAKDCIDEVKDSGSIVHFIALGPLADLAVTNMSILTGGNHKLATDEAQNNGLIDAFGALASENADITQKSLQLESKGAILNNSLWLNDTVVIDSTLGRDTFFLVTWSKQAPAIYLRDPKGTQTTNFTMDSASKMAYLSIPGTAQVGVWTYNLEAKENSEILTITVTSRAANSSVPPITVNAKVNTDTNTFPSPMIVYAEVLQGYTPIIGARVTATIESNSGKTEELVLLDNGAGADAFKDDGVYSRFFTAYSVNGRYSLKVRADGGRNSARRSLRHPSSRAAYIPGWVVDGEIQGNPPRPETTEATQPVLENFSRTASGGAFVVSNVPSGPLPDLYPPNQITDLQATLDGEEISLTWTAPGDDYDVGRVQQYIIRTSKNIIELRDNFNNSPRVDTTNLTPKEANSEETFAFKPENITEENATYIFIAIESVDKSSLSSGPSNIAQVALFTPQAEPDPDESPSSSGVSVATIVLSVLGALVLVCIIVGTTICILKNKRSSSAAITKF
Protein: RIKEN cDNA 2310061I04 gene (F6W3U3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
XINEILNIRTKGRTFYVMSLTLCRFLVWNYFAQFRLEILQLTRHPENWTLQARWRLIGLPIHMLFLRFYRRDKEDLYRTFDAFSTFYLNSSGLICRHHLDKVSVGRGKG
Protein: Sm domain-containing protein (D4PH96)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MCVSSAVCVLSRLSLERFSNFSANFVDNFLLVARFARGETLKNGIVLEISKICPKLLLILNFHYRCEIAVFKIQIFSIFRYISPVPKLFDCSTDNLLFIYILFASKVRMKEMSTPTGLPALNGDVLSAINDMIGRVIIINTTDKKRYSGVLGAVSQDFDFGMQCVVEITKENENNLLRTESECRDKMVFHYSDIVDFAYVTQEIKKQHAVSKFVTDRQYHGDTPIEGEELQEWNGGEEDGLGGSIEDDVVVAGGQTAARRSNNHNNGTGWSVNDMFAANEKMNVVSTFKEDLTQYTTVEVVGTDEDRARAERLAREIESNSSSKFMANLENDDDERDLDKITRQEDFENGNGRKRNNNSFNQQQQQRRNPNIAPNGQPVNRRAEGLRGDRRNSGSSSANNSRYGAPAAAQQNYSQNQQQQQGQKGYRRQNEENDWQMAKGKGQNQGHDHSFRQQQKQMLDPRPNNNVKPADDKAQSATTATAAAGGSRVTDLKNWGNEFSIATAPKDQAPAVPAGNSGSAWNRGPPSSLVAKGSSNESTPPPTTNGEEAETKKEEAPSTSVDVAAAPVQNVQNDAEKHQEDDNVSVTSENDSVITSKSSSFKFNINAPEFKPRVAPATPTATTPVQNEYHPQQQPHPAMMAPQQGPPAPGMGMVPPHMGGPQNQGQPPMMMWQQTGQQQQGGGGYPQNHQFPIQHVPMQGVPGQMYGPGAATPVTVAQQPNQQHQVPTSAAGGQNHQLRDGEYREKQPLYMPYGPPQMVPVTSQQFYHSQYQGQMQQAAPYQMKMMPQQAPQGAYQQRYQQPQVYMMPPQGQQQQPRYQGPPPPQQQQQQQPQQQQFSGEQSRPQSHPNSQPTTPGPRGELPKMSGAPQNGNMQAESSSNASHSGSTSSQSGQRSGSPPGAVPPPPPPQQQHQQQQHPPHHAPPHVGAPPPQMMQQQQQHIQQYMVMQGPHQMHPQIPNYYQQPQALFYPMIMPQQMPMQQNQHPQQSLMGERSDQGFPTSGYFDYRTMPNYQQQQQQQQQQMHRQNSLPQQFQGNQGVNPSGQQSGPPPPPPPSQQGTPRDQQHSQSPP
Protein: Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase) (I3LK75)
Organism: Sus scrofa (Pig)
Function: Involved in the catabolism of quinolinic acid (QA).
Interaction partners:
- Nicotinamide-nucleotide adenylyltransferase
- Nicotinamide nucleotide adenylyltransferase 2.
- Nicotinamide riboside kinase 1.
- Glutamine-dependent NAD
- Nicotinamide riboside kinase 2
- 3-hydroxyanthranilate 3,4-dioxygenase
- Nudix hydrolase 12.
- Kynureninase
- Cytosolic purine 5'-nucleotidase
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
Sequence:
MDPEGLALLLPPATLATLADSWLREDCPGLNPVALVTGAAPSQAVLWAKSPGVLAGRPFFDAIFAQVNCQVSWFLPEGSKLVPVAKVAEVQGPAHCLLLGERVALNMLARCSGVASAAATAVETARGTGWAGHVAGTRKTTPGFRLVEKYGLLVGGATSHRYDLGGLVMVKDNHVVAAGGVEQAVQGARRAANFALKVEVECSSLQEALEAAEAGADLVLLDNFRPEELHPTAAALKAQFPTVGVEASGGVTLDNLPQFCGPHIDVISLGMLTQAAPALDFSLKLFAEGTTPVPYARKS
Protein: Ngfi-A binding protein 2 (D4A4F4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- E3 SUMO-protein ligase EGR2
- Chromodomain-helicase-DNA-binding protein 4
- Early growth response protein 1
- Early growth response protein 3
- Early growth response protein 4
- DNA helicase
Sequence:
MHRAPSPTAEQPPGRADNTRRTPQPRVKASASTMALPRTLGELQLYRVLQRANLLSYYETFIQQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALREWATNPGLFSQPVPAVPVSSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSPKSPLELGEKLSPLPGGPGAGDPRIWPGQSTPESDVGAGGEEEAGSPPFSPPAGGGVPEGTGAGGVAAGGTGGGPDRLEPEMVRMVVESVERIFRSFPRGDTGEITSLLKLNKKLARSVGHIFEMDDNDSQKEEEIRKYSIIYGRLDSKRREGKQLSLHELTINEAAAQFCMRDNTLLLRRVELFSLSRQVARESTYLSSLKGSRLHSEELGGPPLKKLKQEVGEQSHTEIQQPPPGPEPYAPPYRPSLEEDSASLSGESLDGHLQEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
Protein: Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS) (Q72AR5)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02002}.
Interaction partners:
- Proline--tRNA ligase
- Phenylalanine--tRNA ligase beta subunit
- Leucine--tRNA ligase
- Arginine--tRNA ligase
- Methionine--tRNA ligase
- Lysine--tRNA ligase
- Glutamate--tRNA ligase
- Valine--tRNA ligase
- Glutamine--tRNA ligase
- Lipoprotein signal peptidase
Sequence:
MSDYKKTLQLPETKFPMKANLTQREPEMLRKWEKDDAYGAMVRASGQQGTYVLHDGPPYANGNIHMGHALNKILKDIIVKSRNLQGFKAEYVPGWDCHGLPIELKVEHELGEKKRTMPAHAVRKRCRQYAEKYLDIQRKEFKRLGVFGAWDKPYVTMHPSYEAATARELGNFAAKGGLVRSKKPIYWCCSCQTALAEAEVEYHDHTSPSVHVRFPLRDPRVAEVLPGVDPAHAYIVIWTTTPWTLPDNMAVAVHPDFDYVVVRHGGDFHIVAEGLLEACLKAFKWDEHEVVARIGGRALEGLKATHPFYDRPSPIVLADYVTLESGTGCVHTAPGHGREDYETGLRYGLDIYSPLTDEGRYLDCVEFFAGMTIFEANPKVIEKLREVGNLLAEGRITHSYPHCWRCKKPVIFRATTQWFIAMERNDLRQKALDAIRDDVRWIPSWGQERIHNMIEFRPDWCISRQRMWGVPIVALLCEDCGEAWNDADWMRDIAERFAKHATGCDYWYETDLSDIVPAGLRCPKCGGDHWKKETDILDVWFDSGTSFAAVVEQREECGFPADLYLEGSDQHRGWFHSSLLASIGTRGVPPYRSVLTHGYVVDGDGRKMSKSVGNVVAPQEIIDKHGAEVLRLWVASVDYREDIRISEEILNRLVDAYRRIRNTCRYLLGNISDLTPETMVPFEAMDPLDRFALDLASRAHERIQDAYTEYEFHKVFHTLHNLCVTDLSAFYLDILKDRLYSSAADSHARRSAQTALYRILMLMVRDMAPVLSFTAEEVFGYVPAALRPDVISVFALPATDAPAFTLDTTSRAAWEKLLAVRSETTKAIEPLRKSGEVGHSLDTHVTLFADPSLKATLEGLGSDLRAMFIVSRLEVMDLADAPADAWTSEELPELKVTVRKAEGEKCERCWIISADLGTDAAHPTLCPRCTAVLTGTGA
Protein: Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed] (Q61771)
Organism: Mus musculus (Mouse)
Function: Microtubule-based molecular motor that transport intracellular cargos, such as vesicles, organelles and protein complexes. Uses ATP hydrolysis to generate force to bind and move along the microtubule. Plays a role in cilia formation. Involved in photoreceptor integrity and opsin trafficking in rod photoreceptors (By similarity). Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit GRIN2A into neuronal dendrites.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}. Cell projection, cilium {ECO:0000269|PubMed:25243405, ECO:0000269|PubMed:9865700}. Cell projection, dendritic spine {ECO:0000269|PubMed:31746486}. Note=Colocalized with GRIN2A in dendritic shafts and in DLG4-positive spines. {ECO:0000269|PubMed:31746486}.
Interaction partners:
- Kinesin-like protein KIF3A
- Kinesin-associated protein 3
- Kinesin-like protein KIFC3
- Kinesin-like protein KIF17
- E3 SUMO-protein ligase TRIM60
- Intraflagellar transport protein 88 homolog
- Intraflagellar transport protein 20 homolog
- Kinesin light chain 2
- Kinesin light chain 1
- Kinesin heavy chain isoform 5A
Sequence:
MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTSHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEDGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKNKIMNRSFFDDEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEPRYRAENIMLLELDMPSRTTRDYEGPAISPKVQAALDAALQDEDEIQVDASSFESTASRKPKARPKSGRKSGSSSSSSGNPASQFYPQSRGLVPK
Protein: F-box domain-containing protein (Q382I2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTHQTHAQGANPPDNAADFCGADDITSPASSNHHGAEHAKRTPVNREYNRAARYRDCSPNYNFEWGSMTEEMTMVGGTEFTERRGEIVVQDDEESIAFRFTNTRKDVLKFRACISYKTHRSTKNAVLPSQVGPFNDEILSVIFLYVSLDMREILNAGQVCRYWRFFANLAPHWTYYNRLDLGRRLMQLPRYLQKMVGRPRIVTRDEYFRERQKAAEFDERATEKSSTQHVRWCIAIALLSAAACAGNFFFSYYVGVRFAERYSDAVLGSIAFLILLGLVIVQVVFIIIPLGTGSTPGEKQNSMRLLAWAAFLLLTGSVLGTITTLTTTRVESTRQLLGAPVVELVPGKGCELVDLSREPAFAILPAPLSDVRWRPITTDKEEKTFLPHCASPGAGEKEVCFVLLYFDELYNSSVFSNHTQLVISKHIGTRYALSFDPFDANSSSRWCETGKRPQTIAVTMPVYVRLVEERNRNYFDDSYLDPLRRPGRISSISYQCSVKYPRIVTEDPPGASEIWYKSQVPWRQHHIPLVTDVENTPLRYLEEHNHFLHYSYACYIAAALLWLFLFVLQCFLRNHALKVLGLATTCTLLVMNPVALLVSGVLCITLSDYYFICNETTGGAMIGTGISLTAFALAAYVCFW
Protein: Kank, isoform E (E1JH70)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASLQIRIVLRRESRKSNSCIGGNQSPTGTPRPFLRSNTLPLRQRPSPAEVQYESYVQATVAANAKSPVEQLESAKSPGAPPPPPPRRHHLLATTPTGKPTFKEDRPQENGSVSSSSLQSPVISETGQTTADAQALFQIREQMALSLRRLKDLEEQVKVIPDMELELNSLRSEKQKLLRRNEELMRSQRQTPSPPSPGLKTASPVQFTPQRISPVSLESLGARMRSSSTSASPSPSVVRRDVSTQAVVRPPATRDVSVGHQPTTRNVGVQPSETVYSKEELDKKVEQALTNAQKQQLRKLISVGTQMYVPQRDQKDSGVQTTPERPKLKYHVGVTVKPATRENFTSCKPDVRHVGSSDDRLDDVLCEKCAVSKRSVACGPETPAEKVKPAPQMPGRSNTFSLGENETVSVVRKTIGCQTPVTLVLSSGSQTTTAVVRSTGAQVNPQQQHSGVQCATEQVSRQTDTKGLQRLTRSQTKAEQVSESVPRPTTRHTASNTDKVEEAEPAKVRTSHSACNTEEVRKRDVGCGDIVKPHISIACAANYCDSCKEAIQDLARGFSKASPTATRTGGAVRRSTSADSRIPRPKHLSSPSPVRKEFMRQNTYTLATPSPTPSPQVERKARLSSLQEKPPSVSSFQASEPLPESQSFIRQPQKDSLDLSLLGEDELIVREEKRVSISWSRDASPAPLMTSSGTTKSESPEQEPAMSSSSDSSPPIDVQIAQGARKKSSTPLKSSQSEGSQVTVIEQPATKAQLHQLAQADSEPRKKTELSQSLKDALKIINDSLLKKLGAKPISSQSLKSAKATIQDHWFTNSSTGKSDPHQVEDYLDYFESLSIPLLEYCVNLSDSNGNTAMHYAVSHGNFDVVSILLDSKVCDVNQMNNAGYTSVMLVSLAKLKQPAHRTVVERLFKMADVNIRAKKVALPDRFDARCVAW
Protein: Submandibular gland protein C (A0A8I6AU37)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
GMHVLIYSFTTSVRGRAGLGTYSRFGLGVLLSGKKTLSAKNSGGNKDDSVSAGGKENSNDALRLGLDGAASVNTNLDASATHRVGGSGSSTTPQKDERSPFDLIKAILRLQGATSGSSKLSVHSTNDPSAEPGDDPTAQGPQATASSTPKQNVDINLSSAGSATSNDGAPTPREQSSADSLLEESQNLGNESPTEASGSGSPMTGVSKENSNDALRLGLDGAASVNTNLDASATHRVGGSGSSTTPQKDERSPFDLIKAILRLQGSGKGGSSAETGSSRGRGRGSGATSGSSKLSVHSTNDPSAEPGDDPTAQGPQATASSTPKQNVDINLSSAGSATSNDGASPAREQSSADPLMEESQNLGNESPTETSGSEDSSNEENLKKVLKAFADRIPQSSTGSSDSADRPNAYSGNSFSGELERIFDSNPTKASVSGKENSNDALRLGLDGAASVNTNLDASATHHVGRSGSSTTPQKDERSLFDLIKAILRLQGSGKGGSSAETGSSRGRGRGSGNGLMLQDQPAPASGRNDKTVDTSGLSTESAISNEENLSGSGDSNKVSGPSSSAVVSTDSGDDGNLEDKQVPRFNGDERDGENNSDFFGAGSLDTGNTSDSGSHNLSSGSGSSVRSNVSIGAGPSDQNESADLGGSGRVTCAGKTVSGASSVA
Protein: Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1) (Q62761)
Organism: Rattus norvegicus (Rat)
Function: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Phosphorylates CLSPN (By similarity).
Subcellular location: Cytoplasm.
Interaction partners:
Sequence:
MDHSNREKDDRQRTTKTMAQRNTHCSRPSGTSTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRSTPIEALCENFPEEMMTYLRYVRRLDFFEKPDYEYLRNLFTDLFERKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPLRNQPRSLTAEWFVLAPLSHPPAPT
Protein: DNA damage tolerance protein RHC31 (RAD31 homolog) (Q06624)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Could be involved in a ubiquitin-related process important for DNA damage tolerance.
Interaction partners:
- SUMO-conjugating enzyme UBC9
- Ubiquitin-like protein SMT3
- Ubiquitin-activating enzyme E1-like
- E3 SUMO-protein ligase SIZ2
- Ubiquitin-like-specific protease 2
- E3 SUMO-protein ligase SIZ1
- E3 SUMO-protein ligase MMS21
- Ubiquitin-like-specific protease 1
- Chromosome stability protein 9
- NEDD8-conjugating enzyme UBC12
Sequence:
MDMKVEKLSEDEIALYDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGIGHLTILDGHMVTEEDLGSQFFIGSEDVGQWKIDATKERIQDLNPRIELNFDKQDLQEKDEEFFQQFDLVVATEMQIDEAIKINTLTRKLNIPLYVAGSNGLFAYVFIDLIEFISEDEKLQSVRPTTVGPISSNRSIIEVTTRKDEEDEKKTYERIKTKNCYRPLNEVLSTATLKEKMTQRQLKRVTSILPLTLSLLQYGLNQKGKAISFEQMKRDAAVWCENLGVPATVVKDDYIQQFIKQKGIEFAPVAAIIGGAVAQDVINILGKRLSPLNNFIVFDGITLDMPLFEF
Protein: BHLH transcription factor (Os01g0196300 protein) (cDNA clone:J033115I17, full insert sequence) (Q5SMX4)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MEDCSSWIHGYANANATAGNNGFMCGYAASCSPVEFQQQQQLVGSQIEHHLNQISMQMGMDDESAVYDGASMVDVLLMASSSPHHHAGAGSFQYSSPTSSSASFRSASVSCSPESSAAATTHFLGPPAPSAAAAGFHYPEVSSQAPLPLPLPPYEPQHGQYTTVLSPPPPAPELPATTTPATGGAFRRYARHLRPRRLPKPGGCGQRMFKTAMSVLTKMHVAATYNRQYYYQQAAAAAASASAAEAPPSGNQLQHMISERKRREKLNDSFLALKAVLPPGSKKDKTSILIRAREYVKSLESKLSELEEKNRELEARLASRPAAAAKNDKGETAAAPAPEAGDETKRKDLVEIEVTTSGGGAGAADAAAAAGGDQETCTLNVDLRGGGGGGGMSTTDVVLRTLQCLREQIGDGASLVAMSTSAGSGGRPPRANLTLQLKV
Protein: Far upstream element binding protein 3 (A0A8I6ACQ5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAELVQGQSAPVGLKAEDFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRAVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDGNSTIQELLIPASKVGLVIGKGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDPFKVQQAREMVLEIIREKDQADFRGVRSDFTSRAGGGSIEVSVPRFVVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAARIINELILTAQEREILGGLTGTRGRGRGRGDWSVGTPGGIQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPNLRIFTIRGAPQQIEVARHLIDEKVGGASLGAPTAFGQSPFSQPPAAPHQNTFPPRAFPNIAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQNSQPDYSKAWEDYYKKQGAVDGHLPRLFPEISVRETCLLQRFLDLQTFR
Protein: Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (P18031)
Organism: Homo sapiens (Human)
Function: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:1739967, ECO:0000269|PubMed:21135139}; Peripheral membrane protein {ECO:0000269|PubMed:1739967, ECO:0000269|PubMed:21135139}; Cytoplasmic side {ECO:0000269|PubMed:1739967, ECO:0000269|PubMed:21135139}. Note=Interacts with EPHA3 at the cell membrane.
Interaction partners:
- Insulin receptor
- Epidermal growth factor receptor
- Insulin receptor substrate 1
- Insulin-like growth factor 1 receptor
- Tyrosine-protein kinase JAK2
- Proto-oncogene tyrosine-protein kinase Src
- Catenin beta-1
- Regulator of microtubule dynamics protein 3
- Insulin receptor substrate 2
- Hepatocyte growth factor receptor
Sequence:
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT
Protein: Structural maintenance of chromosomes protein 6 (DNA repair protein rad18) (P53692)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Non-structural maintenance of chromosomes element 1
- Structural maintenance of chromosomes protein 5
- Non-structural maintenance of chromosome element 4
- E3 SUMO-protein ligase nse2
- Non-structural maintenance of chromosome element 3
- BRCT-containing protein 1
- Non-structural maintenance of chromosome element 5
- Non-structural maintenance of chromosome element 6
- Structural maintenance of chromosomes protein 3
- DNA topoisomerase 2
Sequence:
MTTELTNVSLEEAITEKTSENRRKRDSDVLQTEEVDLSNVKRIRASRNQDNRPERQSRLQRSSSLIEQVRGNEDGENDVLNQTRETNSNFDNRVGVIECIHLVNFMCHDSLKINFGPRINFVIGHNGSGKSAILTGLTICLGAKASNTNRAPNMKSLVKQGKNYARISVTISNRGFEAYQPEIYGKSITIERTIRREGSSEYRLRSFNGTVISTKRDELDNICDHMGLQIDNPMNILTQDTARQFLGNSSPKEKYQLFMKGIQLKQLEENYSLIEQSLINTKNVLGNKKTGVSYLAKKEEEYKLLWEQSRETENLHNLLEQKKGEMVWAQVVEVEKELLLAEKEFQHAEVKLSEAKENLESIVTNQSDIDGKISSKEEVIGRAKGETDTTKSKFEDIVKTFDGYRSEMNDVDIQKRDIQNSINAAKSCLDVYREQLNTERARENNLGGSQIEKRANESNNLQREIADLSEQIVELESKRNDLHSALLEMGGNLTSLLTKKDSIANKISDQSEHLKVLEDVQRDKVSAFGKNMPQLLKLITRETRFQHPPKGPMGKYMTVKEQKWHLIIERILGNVINGFIVRSHHDQLILKELMRQSNCHATVVVGKYDPFDYSSGEPDSQYPTVLKIIKFDDDEVLHTLINHLGIEKMLLIEDRREAEAYMKRGIANVTQCYALDPRNRGYGFRIVSTQRSSGISKVTPWNRPPRIGFSSSTSIEAEKKILDDLKKQYNFASNQLNEAKIEQAKFKRDEQLLVEKIEGIKKRILLKRREVNSLESQELSVLDTEKIQTLERRISETEKELESYAGQLQDAKNEEHRIRDNQRPVIEEIRIYREKIQTETQRLSSLQTELSRLRDEKRNSEVDIERHRQTVESCTNILREKEAKKVQCAQVVADYTAKANTRCERVPVQLSPAELDNEIERLQMQIAEWRNRTGVSVEQAAEDYLNAKEKHDQAKVLVARLTQLLQALEETLRRRNEMWTKFRKLITLRTKELFELYLSQRNFTGKLVIKHQEEFLEPRVYPANRNLATAHNRHEKSKVSVQGLSGGEKSFATICMLLSIWEAMSCPLRCLDEFDVFMDAVNRLVSIKMMVDSAKDSSDKQFIFITPQDMGQIGLDKDVVVFRLSDPVVSSSALPPSTAP
Protein: BTB/POZ domain-containing protein 18 (A0A0A6YY25)
Organism: Mus musculus (Mouse)
Function: Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Acts by facilitating transcription elongation at piRNA loci during pachytene.
Subcellular location: Nucleus {ECO:0000269|PubMed:28292424}.
Interaction partners:
Sequence:
MCSPASSKILYRNPRFLRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLEMGGLKIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNRECLQPPAAAPISARVVGPKSRPQTPLPVTQTPSPLGAVRLKSLGEEEGAHKKTNLPNADSLSDTQLKKKARVCLTQESRSSPSSQREGPKETKSNPGPTALPSLYPSVDEQLLPRKIRLSRSKPSPHVYTSTPSSILSGPSSMPTAPGRRLWRQRTVSKEAQGVDKQKPGEVRPLQSTPDPSDVGKPAENKKQSPELRAPTSSSVEEGQVGRVKLRKIVNGTCWEVVQEPPLRNTQDSPQILEPSDVEEPSGTLLSSVNEQEIPARIQLCQDSPESPRLQDILLSASHSPDHPMVKSEFGSSPMLTGKESDLNIDCREPYTFDTTLLGQPCEAEQYRITSAAATSELEEIFDFMLCGSDVEPPVGSLESPGAEGCRTPSYHLSETGKNWIEGEEWCLPDMELWPRDLTGLEKEPVSENKEPVEPFSPLVMRSENTESFEPLSPLVMPSEVSREELSLRGSWTPDLEITSSQPLDGQGEKLLHFDSSDPSQRSYNHLSPPCSDWAETGLEVSLGMDDVLCPVPKAVREVSANPEQLDPLPGSSEDEEIDVVDWTVEKKLGPTSVPSVWPDPSSESETEVDILT
Protein: Conserved protein (O06802)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- L-gulono-1,4-lactone dehydrogenase
- Conserved protein
- Probable trans-aconitate 2-methyltransferase
- Possible conserved exported protein
Sequence:
MHEVAAREQRSDGPMRLDAQGRLQRYEEAFADYDAPFAFVDLDAMWGNADQLLARAGDKPIRVASKSLRCRPLQREILDASERFDGLLTFTLTETLWLAGQGFSNLLLAYPPTDRAALRALGELTAKDPDGAPIVMVDSVEHLDLIERTTDKPVRLCLDFDAGYWRAGGRIKIGSKRSPLHTPEQARALAVEIARRPALTLAALMCYEAHIAGLGDNVAGKRVHNAIIRRMQRMSFEELRERRARAVELVREVADIKIVNAGGTGDLQLVAQEPLITEATAGSGFYAPTLFDSYSTFTLQPAAMFALPVCRRPGAKTVTALGGGYLASGVGAKDRMPTPYLPVGLKLNALEGTGEVQTPLSGDAARRLKLGDKVYFRHTKAGELCERFDHLHLVRGAEVVDTVPTYRGEGRTFL
Protein: Vacuolar morphogenesis protein 7 (P32912)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.
Subcellular location: Vacuole.
Interaction partners:
- Vacuolar protein sorting-associated protein 41
- Vacuolar membrane protein PEP3
- Alpha-soluble NSF attachment protein
- Protein transport protein SEC22
- Vacuolar morphogenesis protein 6
- Syntaxin PEP12
- Vacuolar protein sorting-associated protein 16
- Vacuolar protein sorting-associated protein 33
- t-SNARE VTI1
- Vacuolar v-SNARE NYV1
Sequence:
MAANSVGKMSEKLRIKVDDVKINPKYVLYGVSTPNKRLYKRYSEFWKLKTRLERDVGSTIPYDFPEKPGVLDRRWQRRYDDPEMIDERRIGLERFLNELYNDRFDSRWRDTKIAQDFLQLSKPNVSQEKSQQHLETADEVGWDEMIRDIKLDLDKESDGTPSVRGALRARTKLHKLRERLEQDVQKKSLPSTEVTRRAALLRSLLKECDDIGTANIAQDRGRLLGVATSDNSSTTEVQGRTNNDLQQGQMQMVRDQEQELVALHRIIQAQRGLALEMNEELQTQNELLTALEDDVDNTGRRLQIANKKARHFNNSA
Protein: SEC14-like protein 2 (Alpha-tocopherol-associated protein) (TAP) (hTAP) (Squalene transfer protein) (Supernatant protein factor) (SPF) (O76054)
Organism: Homo sapiens (Human)
Function: Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
Subcellular location: Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
Interaction partners:
Sequence:
MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK