wanglab/gogpt-training-data huggingface dataset:
Protein: UV-damage endonuclease (UVDE) (EC 3.-.-.-) (Q10988)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Endonuclease for the repair of UV-irradiated DNA. Involved in the excision of cyclobutane pyrimidine dimers (CPD) and 6-4 pyrimidine pyrimidones (6-4PP) which forms the UV damage repair (UVDR) pathway. Functions also in oxidative damage repair in vivo. Provides back-up AP endonuclease activity to apn2 together with apn1.
Interaction partners:
- DNA repair protein rad13
- DNA-
- Flap endonuclease 1
- Apurinic-apyrimidinic endonuclease 1
- Endonuclease III homolog lyase)
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- ATP-dependent DNA helicase hus2/rqh1
- DNA repair protein rhp26
Sequence:
MLRLLKRNIQISKRIVFTILKQKAFKGNHPCVPSVCTITYSRFHCLPDTLKSLLPMSSKTTLSMLPQVNIGANSFSAETPVDLKKENETELANISGPHKKSTSTSTRKRARSSKKKATDSVSDKIDESVASYDSSTHLRRSSRSKKPVNYNSSSESESEEQISKATKKVKQKEEEEYVEEVDEKSLKNESSSDEFEPVVPEQLETPISKRRRSRSSAKNLEKESTMNLDDHAPREMFDCLDKPIPWRGRLGYACLNTILRSMKERVFCSRTCRITTIQRDGLESVKQLGTQNVLDLIKLVEWNHNFGIHFMRVSSDLFPFASHAKYGYTLEFAQSHLEEVGKLANKYNHRLTMHPGQYTQIASPREVVVDSAIRDLAYHDEILSRMKLNEQLNKDAVLIIHLGGTFEGKKETLDRFRKNYQRLSDSVKARLVLENDDVSWSVQDLLPLCQELNIPLVLDWHHHNIVPGTLREGSLDLMPLIPTIRETWTRKGITQKQHYSESADPTAISGMKRRAHSDRVFDFPPCDPTMDLMIEAKEKEQAVFELCRRYELQNPPCPLEIMGPEYDQTRDGYYPPGAEKRLTARKRRSRKEEVEEDEK
Protein: CCR4-NOT transcription complex subunit 11 (Q8MLP8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- CCR4-NOT transcription complex subunit 10
- CCR4-NOT transcription complex subunit 3
- Regulator of gene activity
- Not1, isoform H
- CCR4-NOT transcription complex subunit 9
- poly
- CCR4-NOT transcription complex subunit 4
- poly
- FI22161p1
- Gametogenetin-binding protein 2-like
Sequence:
MFLSIAPPLMDFEDELLWINQSNSDKVEIIYDKSNYITPNIKHLIEQAFLQPLSLQNQHILFDDLLKQNTDIARQYGLTPDKLPLLVESNPLISIEILLRLMTTSDITEYFNVLVNMDITLHSMEVVNRLTTSGPLPTEFIHLYISNCISTCETVKDKYMQSRLVRLVCVFLQSLIRNKIVNVRVCATTISSTVLSDYSIVIFQELFIEIEAFCVGFSKIKEAATLYRLIKHLETGESALSSNSLAK
Protein: RH42690p (Q9W3X8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform B
- U1 small nuclear ribonucleoprotein 70 kDa
- Pre-mRNA-processing factor 39
- BcDNA.LD23634
- Probable small nuclear ribonucleoprotein Sm D2
- U1 small nuclear ribonucleoprotein C
- Small nuclear ribonucleoprotein F
- Probable small nuclear ribonucleoprotein G
- LD24714p
- Splicing factor 3B subunit 1
Sequence:
MVDAARQMLDELMGRNRNLHPSEAGAKVNWEDPEFCQFYNVKFCPHDLFINTRADLGPCARIHDEEARHLYEDARPSQRKRQYEDEFLRFCNVMLHDVDRKIQKGKQRLLLMQRDQPNVPAPLSRHQEQLANLTARINKLLSEAEEAGIRGDVDQAQDLMTVCEELKEEKEQLVQQYEAHHKAISSISLTKSAEDELQHHPRSSPVTNPSEESPTTPLPAATTLDEAPDAAPSSAQAAVTTTDDAGEAAGAASEDKTSEKTDSKAAGWSHDAMPEKQMKVCEICGAFLIVGDAQQRIEDHLMGKQHLGYSKLRNAVAEINEARQKEREQEERRRREGRVQRFHSYDSRREPRSEYRERSRDYVQNRQPSDRRHHHHKSHHSSHHSYSRSGGGGGGVGVGGGGGGGSSRSNRSHHNHNHNHYRHDSRERHCRSRSRSRY
Protein: Probable acyl-CoA dehydrogenase FadE25 (EC 1.3.99.-) (P9WQG1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- 3-hydroxyisobutyryl-CoA hydrolase
- Electron transfer flavoprotein subunit alpha
- Electron transfer flavoprotein subunit beta
- Probable fatty-acid-CoA ligase FadD36
- N5-carboxyaminoimidazole ribonucleotide synthase
- N5-carboxyaminoimidazole ribonucleotide mutase
- Probable fatty oxidation protein FadB
- Possible iron-regulated short-chain dehydrogenase/reductase
- Proline-rich antigen homolog
- 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA lyase
Sequence:
MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
Protein: 18S rRNA (guanine-N(7))-methyltransferase RID2 (EC 2.1.1.309) (Protein ROOT INITIATION DEFECTIVE 2) (Q9LVD0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protein. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity (By similarity). Involved in the pre-rRNA processing steps in the nucleolus leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Supports cell proliferation. Required for the initiation of lateral root primordia formation and for the root apical meristem (RAM) organization as well as for leaves development. During callus formation from hypocotyl and root explants, required for the initial stage of reactivation of cell proliferation in the hypocotyl stele. Involved in leaf polarity establishment by functioning cooperatively with AS2 to repress abaxial genes ARF3, ARF4, KAN1, KAN2, YAB1 and YAB5, and the knox homeobox genes KNAT1, KNAT2, KNAT6, and STM to promote adaxial development in leaf primordia at shoot apical meristems at high temperatures.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:21401745}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:O43709}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O43709}. Cytoplasm {ECO:0000250|UniProtKB:P25627}. Nucleus, nucleolus {ECO:0000269|PubMed:21401745}.
Interaction partners:
- Bystin
- RNA-binding NOB1-like protein
- At3g49990
- At3g13230
- Multifunctional methyltransferase subunit TRM112 homolog A
- At1g42440/F7F22_7
- Probable cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG6
- Multifunctional methyltransferase subunit TRM112 homolog B
- Small ribosomal subunit protein eS6z
- Small ribosomal subunit protein uS12y
Sequence:
MSNRPELLAPPEIFYDDTEARKYTSSSRIVEIQAKLSERALELLALPEDGVPRFLLDIGCGSGLSGETLSEDGHHWIGLDISASMLHVAVEREVEGDLLLGDMGQGLGLRSGVIDGAISISAVQWLCNADKSSHEPRLRLKAFFGSLYRCLSRGARAVFQVYPENIAQRELILRQALQAGFGGGLVVDYPHSTKKRKEFLVLTCGTVQTSIQTSKNEYDESCSEDDNSDDEESEEVGVSDRNRPRKRQRTNTKVKGREWVLRKKEQSRRKGKNVPADSKFTSRKRRTRF
Protein: N-ribosyldihydronicotinamide:quinone dehydrogenase 2 (Q5TD07)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
Protein: Amino-acid permease GAP3 (A0A1D8PN88)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Amino-acid permease that is able to transport phenylalanine.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21764911, ECO:0000269|PubMed:28028545}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MTTKEKDEFNIGSLQNSPESSTNMSPDVITTPISKWQAFKDSFKPPEQKPLASSSSSTSSLSASSPHHNDVANNYDIEKSLRPDQQGELKRELKNRHVQMIALGGSVGTGLLIGSGGALHQGGPAALLIAWGITGTMVFCIIHSLGELCVAFPVNGAFSTYANMFVDSSWAFAVGWNYAIMWLIVLPLELVAAAMCITYWNDEINPASWVAIFYVLIVVINIFGVKYYGDAEMYLTIFKIIAIVGFIILGVVLVCGGGPTHEFIGNKYWKQDGAFANGFKGVATTFVTASYSMAGSEMVGLASAEVANPQKSLPKAIRQVFWRIFLFYFLSLTFIGLLVPSNSPQLLGASGTSASPFVIAIKNGGIYALPSIFNACILLSVLSVGNSAVYGCSRTIQSLGAQGLGPKIFAYVDRKGRPLGGLVMSAIFGLLCFLSAYHDEATIFNWLLSVAGLATIFSWFNIGLCHVRFRLALRKQGRSLQELTFTALTGVWGSVYSMIFLCVVLVIQFWTALFPLGSKGKANAENFFQNYLGAVVILIFYVGHKLYTRNWKLCVKLEDIDLDSGRRSFDLDLIRAEIEEEKAANKAKPLYKRLWNYWC
Protein: Cyclin-dependent kinase 7 (EC 2.7.11.23) (Cell division protein kinase 7) (D6RAD4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
Protein: Zinc-regulated protein 8 (P40021)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the integrity functions of RAM, a conserved signaling network that regulates maintenance of polarized growth and daughter-cell-specific transcription.
Subcellular location: Cytoplasm. Bud. Bud neck. Bud tip. Note=Localized to the cortex of small and large buds during bud growth, to the bud neck during mitotic exit and to the tips of mating projections in pheromone-treated cells.
Interaction partners:
- Protein SSD1
Sequence:
MRSFIKAHKKSTSFDESPKRHSNFSGNTNNSSQRSSDDSLDFLPSTPSQMNYDSIPPPAKHSPGFESFHRLANKTSKLFKKTSNSNLNSHLASTPTTSTNQTTSNSFVLQNPPTKNTGPPPPLPPPLFPSSSTSSFSRHDNESEYTAYKKTSPAKDFNRTTDSLPAIKGTITHSWGDSKVESHVIILNDPASPASNTSEATSSKQFKTPIIGNENLTSTTSPSNLEPAIRILNKNKGKQQENIDDAEDGSSKKEHHVYKALALAKNRNRQARIHSHDDIINLGKASQMDMSLLAAAFSGNSTTTINNDQSSNEQTDEKILDIERVTTTSTLTSSETTSPINKSPCFYSQTLSLSPKIRHGDLQSSPSKVNKNDSQNETLNKKKVRISLNRKEEEKVYSLNNNSDEYSVNEKETHKANDCNDESSENGDGDNDHDDDYDDDDDDDDDDDESEFSFEYAGINVRTSSVKYYSKPEPAANVYIDDLYEDENFDDDMNCIEDDESGNEGNEICGLSTRFEETSLKSNKVKKFNDLFNLSDDDEEEDGKDNSNNGDENESDNLYQKRLENGKETFNGNHGGHHDDASLGETVDNKEQFLINDNVKKPIQKYNDLFDLSDEDDNDDKEMSEAESYMFSDEAPSIESGPANAKSTRGIYSQSNKNIIRDGKPNYSFSLKRNNSDDETEHTSAIKASLTGTTGSTKPTVKSFSDIFNVDDSASDAESDSGTGGNNSNGLVSNDSERQVSLQSSLYETKSESHPPNHPHSQILQTPAKIVITPSVSDAQSQALAITDDDGEDDDDDTSSILRTPFQLIDSSHSQQPHYASPQYTAVLNSPPLPPPARSQSLKYHDLNCDLDSEVPRPMSNLFFIDEAEEDEYNQKSKFFDFDHYDIDEINGIPEDFNFSDSERDDLNRRTLKSPLRGGSKNREVSPFSSVSSSFRSTHSFNGKLTINQGAKELAPMKNKIELTNKTVTFFNSNNWNTYDCNSLSRKTSSQMRDSKYQNHNVGQNVEPSSVLSPQHQISNGLDGKCNDNYVISPNLPTTITPTNSFTKPTPEFSNDYSLSPIQETPSSVQSSPKRA
Protein: Translocation protein SEC62 (Q5AI21)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Required for preprotein translocation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Protein-transporting protein
- Protein transport protein SEC61 subunit alpha
- Sec63 complex subunit
- Translocon subunit
- Sec63 complex subunit
- Protein transport protein Sec61 subunit beta
- Ssh1p
- Endoplasmic reticulum chaperone BIP
- Signal recognition particle receptor subunit alpha homolog
Sequence:
MSAPTPPQTGQFQVATSAQRSPVAVNIVNYLFQNPILKQRTGLLDNTNDIEFFRFKRLQRALLSDDYKQKQQNPKNGLIPVANNEDVQKVFVLLIQNQLLLPLQKLHYAEVKAVKGWKPNKEKPTLKRADKAVMDPDVYYGWLYQKPNPYILLYSFLAIAGVFAVILFPLWPNFMKRGVWYLSMGALGLIALFFATAIVRLIIYIISLVAFPKPFWLFPNLFEDCGVIESFQPVYAWEEPKKKKGKKKKEPKLEVVEEKVGSSSGDVKVTGSELSNGSSTTGKRKVTLEEVEE
Protein: Membrane protein insertase YidC (Foldase YidC) (Inner membrane protein YidC) (Membrane integrase YidC) (Oxa1Ec) (P25714)
Organism: Escherichia coli (strain K12)
Function: Inner membrane protein required for the insertion and/or proper folding and/or complex formation of integral inner membrane proteins. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex, as well as at least 2 lipoproteins. Its own insertion requires SRP and is Sec translocase-dependent. Essential for the integration of Sec-dependent subunit a of the F(0)ATP synthase, FtsQ and SecE proteins and for Sec-independent subunit c of the F(0)ATP synthase, M13 phage procoat and the N-terminus of leader peptidase Lep. Probably interacts directly with Sec-independent substrates. Sec-dependent protein FtsQ interacts first with SecY then subsequently with YidC. Sec-dependent LacY and MalF require YidC to acquire tertiary structure and stability, a chaperone-like function, but not for membrane insertion. Stable maltose transport copmplex formation (MalFGK(2)) also requires YidC. Partially complements a Streptococcus mutans yidC2 disruption mutant.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:11821429, ECO:0000269|PubMed:16079137}; Multi-pass membrane protein {ECO:0000269|PubMed:11821429, ECO:0000269|PubMed:16079137}. Note=Predominantly localized at cell poles at all stages of cell growth.
Interaction partners:
- Protein translocase subunit SecD
- Sec translocon accessory complex subunit YajC
- Protein translocase subunit SecY
- Protein-export membrane protein SecG
- Protein translocase subunit SecF
- Protein translocase subunit SecE
- Protein translocase subunit SecA
- Putative membrane protein insertion efficiency factor
- Signal recognition particle protein
- Signal recognition particle receptor FtsY
Sequence:
MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
Protein: 2-Hydroxyacid oxidase 1 (HAOX1) (EC 1.1.3.15) (Glycolate oxidase) (GO) (GOX) (Glyoxylate oxidase) (EC 1.2.3.5) (Q9UJM8)
Organism: Homo sapiens (Human)
Function: Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate. The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones. Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, albeit with much lower catalytic efficiency. Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. Is not active on L-lactate and 2-hydroxybutanoate.
Subcellular location: Peroxisome matrix {ECO:0000269|PubMed:10777549}.
Interaction partners:
- Alanine--glyoxylate aminotransferase
- Glyoxylate reductase/hydroxypyruvate reductase
- 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
- Glycerol-3-phosphate phosphatase
- 2-Hydroxyacid oxidase 2
- Catalase
- D-amino-acid oxidase
- Albumin
- Alanine--glyoxylate aminotransferase 2, mitochondrial
- Diphosphomevalonate decarboxylase
Sequence:
MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLAVSKI
Protein: Yellow mounds protein A (YELA) (Q23925)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Plays as essential role in regulating terminal differentiation.
Interaction partners:
- Eukaryotic translation initiation factor 4 gamma
Sequence:
MSQSDPLNVVSRILNKISKDNFQVLIDQLVSKCQLLDKNESTLFINNIFEKVVEEPSSSSYYIQIINKIQPIFQQNFSIGVGNKLVENFNKRYQILTDQINSNEETFDFNSSKQSFLNLCKFMGECYYTLPSSFLVDVVNNHLPQVTKETADDMTLQQLMEIEIIATSFTSAGKTIESMGGFSSKHENNKTHNNNNNNNNHDHDDDDHDEEDNENNYENTTSTTNNINNNNIQSRENDLHFKGIQKALEDATSVLSFLIENRQLLPPRVRFMVKNLFELKNNKWIIPKAINDDLNAQREVVKVATNHGKTISKSLSEKCDDDSTLNTIFWKSFFQALGIQNYKILRQLMLDDKSNISPSSTSPTIPLSPFLRRSMNITSPSQFNLNNCNNNNNSININNNNMDIDASFDLNDGLMESSSNNNNSNSQLQFSLSSSSGIKDNHNVPTIDLNTISSNNNQQINLPSGFLSPKVARSNSPSLSSVVKQPQSQQNNNNNNNNNNNNTTITTTTSSNNNINNNNNNNNNNKIKESPELSSAPDSNLSVIVSIIDSKIWTPQKEIWKKKIMNKIIPMKSILKKPQKIEILAAIWQNMCDNNYEYGSYLDLCLNLIKMDEGDISPLYSLDGGNVPPVKPYQQSAQPPPPPPSSSSSSAQQPPNEPVNPLLNKLKGPNRRSSMATLQMKPSGISEARRSSISVPFELNRRGSLSGDIPSYCPPAPKLKSTPTLKSTPAIVQNGGSITSTSSSSSSSSSSSSSTTKNIHPTSESKKQPIAKKHKPDLDSFKDVLISSLQDDFALKMFVKKRSLTTYMELLKDLYREFIIEIPLLLKCISLVHNGLYELTDEECTMLFDLEEMAQEQQNLEKQNDQQQNLLTQNNQIFQWKTNTWEEKPQTPPPPPTSYFDLGSDVFVL
Protein: Expressed protein (Nucleic acid-binding, OB-fold-like protein) (Q8RYC3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Nucleic acid-binding, OB-fold-like protein
- Uncharacterized protein At4g28440
- F11M21.26 protein
- F5O8.30 protein
- Replication protein A 70 kDa DNA-binding subunit A
- Replication protein A 70 kDa DNA-binding subunit D
- Replication protein A 70 kDa DNA-binding subunit C
- Replication protein A 70 kDa DNA-binding subunit B
Sequence:
MASNTSNDNFQHRPRQRNGPPPPRRQGRNPPPPSSSTRTSQNQPPQHTPQEKKKPVFVKVDQLKPGTSGHTLTVKVVDQNSVPQKPGAASSSHLRPARISECLVGDETACILFTARNDQVELMKPGATVNLRNAKIDMFKGSMRLAVDKWGRIEATEPADITVKEDNNLSLVEYELVNVVEE
Protein: Semaphorin-6B (Semaphorin VIB) (Sema VIB) (Semaphorin-N) (Sema N) (O54951)
Organism: Mus musculus (Mouse)
Function: Functions as a cell surface repellent for mossy fibers of developping neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons.
Subcellular location: Cell membrane {ECO:0000305|PubMed:20484647}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Plexin-A2
- Neuropilin-1
- Neuropilin-2
- Plexin-A3
- Plexin-A4
- Plexin-A1
- Plexin-B1
- Plexin-D1
- Hepatocyte growth factor
- Plexin-C1
Sequence:
MWTPRVPPPRPALSFFLLLLLGVTYGLFPEEPPPLSVAPRDYLSHYPVFVGSGPGRLTAAEGAEDLNIQRVLRVNRTLFIGDRDNLYQVELEPSTSTELRYQRKLTWRSNPSDIDVCRMKGKQEGECRNFVKVLLLRDESTLFVCGSNAFNPICANYSMDTLQLLGDSISGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVILAVFSTPSNSIPGSAVCAFDMNQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDEILNFVKTHPLMDEAVPSLGHSPWIVRTLMRHQLTRVAVDVGAGPWGNQTIVFLGSEAGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRPSSAGEWGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQLYSGCMKNCIGSQDPYCGWAPDGSCIFLRPGTSATFEQDVSGASTSGLGDCTGLLRASLSDDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGGSEAVLSVSRLGERRGTGPGGRGGAGGGPGGPPEALLAPLMQNGWTKAALLHGGPHDLDTGLLPTPEQTPLPQKRLPTPHPHAHALGSRAWDHSHALLSASASTSLLLLAPARASEQPQVPAEPGPESRLCAPRSCRASHPGDFPLTPHASPDRRRVVSAPTGPLDPSVGDGLPGPWSPPATSSLRRPGPHGPPTAALRRTHTFNSGEARPGGHRPRRHPPADSTHLLPCGTGERTAPPVP
Protein: Leiomodin-1 (Smooth muscle leiomodin) (SM-Lmod) (A0A0G2K0D3)
Organism: Rattus norvegicus (Rat)
Function: Required for proper contractility of visceral smooth muscle cells (By similarity). Mediates nucleation of actin filaments (By similarity).
Subcellular location: Cytoplasm, myofibril, sarcomere {ECO:0000269|PubMed:10520227, ECO:0000269|PubMed:11350761}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10520227, ECO:0000269|PubMed:11350761}. Note=Colocalizes with actin filaments in sarcomeres. {ECO:0000269|PubMed:10520227, ECO:0000269|PubMed:11350761}.
Interaction partners:
- Actin, aortic smooth muscle
- Tropomyosin alpha-1 chain
- Non-muscle caldesmon
- Actin, gamma-enteric smooth muscle
- Calponin-1
- Myosin regulatory light polypeptide 9
- Myosin light chain kinase, smooth muscle
- Tropomyosin beta chain
- Myosin-10
Sequence:
MSKVAKYRRQVSEDPDIDSLLSTLSPEEMEELEKELDVVDPDGSIPVGLRQRNQTDKQPSGSFNREAMLNFCEKESKKIIQREMSVDESKQVGRKTDAKNGEDKGSNASRKALGPRQDSDVGKEPKKGVLKKSFSRDREEADSRGSEKPKEEKVIRGIDKGRVRAAVDRKEAGKDGREERAAATTKKEEEKTGSVRNAGLSRDKDKKREEVKEPSKKEEVKLTAENRSTVGRQEDGKQKESREDRDKKPEVKGIGCGSRDSRKEDEKVKKEETQPDKGVREEGKTREKQPPSGPSKPSDGQARAEEEAAPSIFDEPLEKVKNNDPEMTEVNVNNSDCITNEILVRFTEALEFNTVVKVFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHITGKGILAIFRALLQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTNLLSRNMDKQRQKRLQEQKQAQEASGEKKDRLEVPKVGALPKGSPKPSPQPSPKSAPKNSPKKAGVPAAPPPPPPPLAPPLIMENLKNSLSPATQRKMGDKVLPAQEKNSRDQLLAAIRSSNLKQLKKVEVPKLLQ
Protein: Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein) (A0A1B0GTB6)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|RuleBase:RU003981}.
Interaction partners:
Sequence:
SHTDSHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEDPASE
Protein: Mitochondrial phosphate carrier protein (Mitochondrial import receptor) (Phosphate transport protein) (PTP) (mPic 1) (p32) [Cleaved into: Mitochondrial phosphate carrier protein, N-terminally processed] (P23641)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transport of phosphate groups from the cytosol to the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein.
Interaction partners:
- ADP,ATP carrier protein 2
- ADP,ATP carrier protein 1
- ATP synthase subunit beta, mitochondrial
- Mitochondrial import receptor subunit TOM70
- ATP synthase subunit alpha
- Non-selective voltage-gated ion channel 1
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Probable ATP-dependent RNA helicase DHR1
Sequence:
MSVSAAPAIPQYSVSDYMKFALAGAIGCGSTHSSMVPIDVVKTRIQLEPTVYNKGMVGSFKQIIAGEGAGALLTGFGPTLLGYSIQGAFKFGGYEVFKKFFIDNLGYDTASRYKNSVYMGSAAMAEFLADIALCPLEATRIRLVSQPQFANGLVGGFSRILKEEGIGSFYSGFTPILFKQIPYNIAKFLVFERASEFYYGFAGPKEKLSSTSTTLLNLLSGLTAGLAAAIVSQPADTLLSKVNKTKKAPGQSTVGLLAQLAKQLGFFGSFAGLPTRLVMVGTLTSLQFGIYGSLKSTLGCPPTIEIGGGGH
Protein: Anon1A3 (Q9U4R3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
GVENLPSVAEAKQNHVDEVKPISEEPGNSSEEVPKAEEPLKSSGETSENGAATETAAAPKEPASVMDVDEDETLVENTPSANKEKALDDEKEPEQKSEEHAAAVLESKDQNEPAKEPTPEPMEVDGSSKGSSDTAQVDTPAIENVSAAPETEAAAKTTESSNDVVEVATEGKETVLEVPAAEPKEAESTVESAEELTETSTVVVTEPKEAASSEEEPSKVVDSAEPKEAESNTDESATPVPIDVSTAPASNDVSKPLEIDTTLVKTADSPAKEPQEICEVKKAEINVNGEPKIVNSSAEVGENAAPKVCN
Protein: Adiponectin receptor protein 1 (Q38A44)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Eukaryotic translation initiation factor 6
Sequence:
MESTVTGEPCHACEKQETTDEHSRCGRGTLPLYHIHSTKVPEYMKDNPYIYTGYRAQYTTMMCLRSFLAVHNESLNVWTHAFGFVVFVLLSILLFTNVVLAREYVWHCVVYGGFSFACLMCMLCSTVYHLFMCHENEAVSLFVELVDYHGISVLIVASYIPLLYIGFACKPYYRAIYMVSIIMFGTLSVVFSSLPSLRDAKYRWIRTTVYILMAVGGIVPLLHFYAFTPHNTESMMPLKGVALMFALYGAGVLFYTSRIPERWFPGRFDIYLSSHQIWHVFVLAAACVHFFSCTALYQQWLVSRHIC
Protein: Ceroid-lipofuscinosis, neuronal 6 (Q3U466)
Organism: Mus musculus (Mouse)
Interaction partners:
- Protein CLN8
- Bis
- Battenin
- Palmitoyl-protein thioesterase 1
- Major facilitator superfamily domain-containing protein 8
- Tripeptidyl-peptidase 1
- Calmodulin-like protein 4
- Cathepsin F
Sequence:
MEAATRRRQLLGAAGGPGVAFVQARHGSVKAEDKDRTAPFHLDLWFYFTLQNWVLDFGRPIAMLVFPIQWFPLNKPSVGDYFHMTYNIITPFLLLKLIERSPRTLPRSIVYVSIITFIMGASIHLVGDSVNHRLLFSGYQHHLSVRENPIIKNLKPETLIDSFELLYYYDEYLGHCMWYIPFFLILFMYFSGCFTTCKAESHMPGPALLLVVPSGLYYWYLVTEGQIFILFIFTFFAMLALVLHQKRRRLFLDSNGLFLLYSFALTLSLVALWVAWLWNDPVLRKKYPGVIYVPEPWAFYTLHVSSQQ
Protein: Protein transport protein Sec13, putative (Q388I4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Protein transport protein Sec31, putative
- Protein transport protein Sec24C, putative
- Protein transport protein SEC23
- Nuclear pore protein
- Nuclear pore complex protein
- ADP-ribosylation factor, putative
- Uncharacterized protein
- Uncharacterized protein
- WD repeat protein mio zinc-ribbon like domain-containing protein
- Nucleoporin
Sequence:
MLHSTRYPSQNRTIGGYGQAAPVAPHDMHQQRQPQQPQQFQQQQPQEHQDIIHDTQFDYYGQQLATASSDRTIGIHTVRDGQMQRVATLIGHEGPVWMVSWAHPRFGTVLASAGYDHKAIVWKEVSQPTRQWRPVHVIDIHQGSVNAVQWAPESPMLATASSDGTVAVTTYEEGAWRESVKLSNNSNNIAHAMGATCVSFAPTCPQLGNGRLLVSGGCDSRVRLWYLPEGGAAGAHPYHFLELLEGHTDWVRDVAFEPLSAATRYAVIASCGQDRSVIIHRKQWSHLTTCIDDRGLRSGEGGRDAMGEVSGGWERSCVLFDEPVWRLSWSPTGGMLVVTTGNSEVFILREGNEFCQPWFKTPLSEYENQNQRVH