wanglab/gogpt-training-data huggingface dataset:
Protein: HECT-type E3 ubiquitin transferase (EC 2.3.2.26) (A0A0G2K105)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGFSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPAPYTDGTGAAAGGGNCRFVESPSQDQRLLVQRLRNPEVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE
Protein: Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) (P42695)
Organism: Homo sapiens (Human)
Function: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.
Subcellular location: Nucleus {ECO:0000269|PubMed:14532007}.
Interaction partners:
- Condensin-2 complex subunit G2
- Condensin-2 complex subunit H2
- Structural maintenance of chromosomes protein 4
- Structural maintenance of chromosomes protein 2
- Condensin complex subunit 2
- Condensin complex subunit 3
- Condensin complex subunit 1
- Histone lysine demethylase PHF8
- Histone H4
- Microcephalin
Sequence:
MVALRGLGSGLQPWCPLDLRLEWVDTVWELDFTETEPLDPSIEAEIIETGLAAFTKLYESLLPFATGEHGSMESIWTFFIENNVSHSTLVALFYHFVQIVHKKNVSVQYREYGLHAAGLYFLLLEVPGSVANQVFHPVMFDKCIQTLKKSWPQESNLNRKRKKEQPKSSQANPGRHRKRGKPPRREDIEMDEIIEEQEDENICFSARDLSQIRNAIFHLLKNFLRLLPKFSLKEKPQCVQNCIEVFVSLTNFEPVLHECHVTQARALNQAKYIPELAYYGLYLLCSPIHGEGDKVISCVFHQMLSVILMLEVGEGSHRAPLAVTSQVINCRNQAVQFISALVDELKESIFPVVRILLQHICAKVVDKSEYRTFAAQSLVQLLSKLPCGEYAMFIAWLYKYSRSSKIPHRVFTLDVVLALLELPEREVDNTLSLEHQKFLKHKFLVQEIMFDRCLDKAPTVRSKALSSFAHCLELTVTSASESILELLINSPTFSVIESHPGTLLRNSSAFSYQRQTSNRSEPSGEINIDSSGETVGSGERCVMAMLRRRIRDEKTNVRKSALQVLVSILKHCDVSGMKEDLWILQDQCRDPAVSVRKQALQSLTELLMAQPRCVQIQKAWLRGVVPVVMDCESTVQEKALEFLDQLLLQNIRHHSHFHSGDDSQVLAWALLTLLTTESQELSRYLNKAFHIWSKKEKFSPTFINNVISHTGTEHSAPAWMLLSKIAGSSPRLDYSRIIQSWEKISSQQNPNSNTLGHILCVIGHIAKHLPKSTRDKVTDAVKCKLNGFQWSLEVISSAVDALQRLCRASAETPAEEQELLTQVCGDVLSTCEHRLSNIVLKENGTGNMDEDLLVKYIFTLGDIAQLCPARVEKRIFLLIQSVLASSADADHSPSSQGSSEAPASQPPPQVRGSVMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTIMVDKYIPNISMCLKDSDPFIRKQTLILLTNLLQEEFVKWKGSLFFRFVSTLIDSHPDIASFGEFCLAHLLLKRNPVMFFQHFIECIFHFNNYEKHEKYNKFPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFADGILPLDLDASELLSDTFEVLSSKEIKLLAMRSKPDKDLLMEEDDMALANVVMQEAQKKLISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMHYLREVMQDYRDELKDFFAVDKQLASELEYDMKKYQEQLVQEQELAKHADVAGTAGGAEVAPVAQVALCLETVPVPAGQENPAMSPAVSQPCTPRASAGHVAVSSPTPETGPLQRLLPKARPMSLSTIAILNSVKKAVESKSRHRSRSLGVLPFTLNSGSPEKTCSQVSSYSLEQESNGEIEHVTKRAISTPEKSISDVTFGAGVSYIGTPRTPSSAKEKIEGRSQGNDILCLSLPDKPPPQPQQWNVRSPARNKDTPACSRRSLRKTPLKTAN
Protein: Transducin/WD40 repeat-like superfamily protein (F4JTP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cullin-4
- WD repeat-containing protein DWA2
- THO complex subunit 6
- DET1- and DDB1-associated protein 1
- DNA damage-binding protein 1a
- E3 ubiquitin-protein ligase KEG
- DDB1- and CUL4-associated factor homolog 1
- Putative cullin-like protein 4
- Cullin-like protein 5
- Protein ABSCISIC ACID-INSENSITIVE 5
Sequence:
MSGRPAKRPRTDHSVVNVWERELGLLPNRSFSNRFSASEDLLRRLGLDKKLDKHKGCVNTVSFNADGDILLSGSDDRQVILWDWQTASVKLSFDSGHFNNIFQAKFMPFSDDRTIVTSAADKQVRYSKILESGQVETSLLGKHQGPVHKLAVEPGSPFSFYTCGEDGAVKHFDLRTRVATNLFTCKEAKFNLVVYLHAIAVDPRNPGLLAVAGMDEYARVYDIRSYRSEGWYNFTQPIDHFCPGHLIGDDHVGITGLAFSDQSELLASYSDEFIYLFTPDMGLGPTPYPSSTKTEERMTPQVYKEHTNRETVKGVNFFGPKCEYVVSGSDCGRIFIWRKKDGELLRAMEADRHVVNCIESHPHMPLMCSSGIDTDIKIWTPGGTEKPLSPGNAKQASGFGNPRWFDGYYVDDDDDSDDESSEESSDDDDSSEEEENGEVDVEITKDDDNDHGDDDDDDDEDDDGDGDGDEG
Protein: Chromosome partition protein MukF (Protein KicB) (P60293)
Organism: Escherichia coli (strain K12)
Function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
Subcellular location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Interaction partners:
- Chromosome partition protein MukE
- Chromosome partition protein MukB
- tRNA 5-carboxymethoxyuridine methyltransferase
- Methylmalonyl-CoA mutase
- Methylmalonyl-CoA decarboxylase
- Macrodomain Ter protein
Sequence:
MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
Protein: N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)] (O15527)
Organism: Homo sapiens (Human)
Function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:17148573}. Nucleus speckle {ECO:0000269|PubMed:17148573}. Nucleus matrix {ECO:0000269|PubMed:17148573}. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells.; SUBCELLULAR LOCATION: [Isoform 1A]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 2A]: Mitochondrion.
Interaction partners:
- DNA repair protein XRCC1
- Endonuclease 8-like 2 lyase Neil2)
- Endonuclease III-like protein 1
- Endonuclease 8-like 1 lyase Neil1)
- DNA repair nuclease/redox regulator APEX1
- Adenine DNA glycosylase
- DNA mismatch repair protein Msh3
- Oxidized purine nucleoside triphosphate hydrolase
- Endonuclease 8-like 3
- DNA ligase 3
Sequence:
MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLRQSRHAQEPPAKRRKGSKGPEG
Protein: Cytohesin-2 (PH, SEC7 and coiled-coil domain-containing protein 2) (Q15795)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
FTDLNLVQSLRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQSAVSVDPFYEILTAREKRISVKKKQEQP
Protein: Kit ligand (Hematopoietic growth factor KL) (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)] (P21581)
Organism: Rattus norvegicus (Rat)
Function: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000250|UniProtKB:P21583}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000250|UniProtKB:P21583}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P21583}. Cell projection, filopodium {ECO:0000250|UniProtKB:P21583}.; SUBCELLULAR LOCATION: [Soluble KIT ligand]: Secreted {ECO:0000250}.
Interaction partners:
- Mast/stem cell growth factor receptor
- Platelet-derived growth factor receptor alpha
- Interleukin-3
- Receptor protein-tyrosine kinase
- Platelet-derived growth factor receptor beta
- Macrophage colony-stimulating factor 1 receptor
- Receptor-type tyrosine-protein kinase FLT3
- Thrombopoietin
- Chymase
- Insulin receptor
Sequence:
MKKTQTWIITCIYLQLLLFNPLVKTQEICRNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVTHLSVSLTTLLDKFSNISEGLSNYSIIDKLGKIVDDLVACMEENAPKNVKESLKKPETRNFTPEEFFSIFNRSIDAFKDFMVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVAASSLRNDSSSSNRKAAKSPEDPGLQWTAMALPALISLVIGFAFGALYWKKKQSSLTRAVENIQINEEDNEISMLQQKEREFQEV
Protein: Replication-associated protein (Rep) (EC 2.7.7.-) (EC 3.1.21.-) (Protein AC1) (Protein AL1) (P03567)
Organism: Tomato golden mosaic virus (strain Yellow vein) (TGMV)
Function: Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
Subcellular location: Host nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MPSHPKRFQINAKNYFLTYPQCSLSKEESLSQLQALNTPINKKFIKICRELHEDGQPHLHVLIQFEGKYCCQNQRFFDLVSPTRSAHFHPNIQRAKSSSDVKTYIDKDGDTLVWGEFQVDGRSARGGCQTSNDAAAEALNASSKEEALQIIREKIPEKYLFQFHNLNSNLDRIFDKTPEPWLPPFHVSSFTNVPDEMRQWAENYFGKSSAARPERPISIIIEGDSRTGKTMWARSLGPHNYLSGHLDLNSRVYSNKVEYNVIDDVTPQYLKLKHWKELIGAQRDWQTNCKYGKPVQIKGGIPSIVLCNPGEGASYKVFLDKEENTPLKNWTFHNAKFVFLNSPLYQSSTQSS
Protein: Ecdysone-inducible gene E1, isoform B (RE39082p) (Q8SWT9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTATARQSATSRKQPAIAMLNGNAFTVKRLLALLIIFTVVDASRSLELGDKCQHDMDCTDFIKGSSCSALGYCECAPYFVQLDSKRCLSSQLLGGDCQLSEQCSMKVANSSCLEGACRCVEGFLQFRKHTCLGRKYQPTAGQLLWP
Protein: Rho GTPase-activating protein SYDE2 (Synapse defective protein 1 homolog 2) (Protein syd-1 homolog 2) (Q5VT97)
Organism: Homo sapiens (Human)
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Interaction partners:
Sequence:
MHDLPPDSGARRGGRGLADHSFPAGARAPGQPPSRGAAYRRACPRDGERGGGGRPRQQVSPPRSPQREPRGGQLRTPRMRPSCSRSLESLRVGAKPPPFQRWPSDSWIRCGAHRDWDEPPPRGGRMDGWSGDRARAAAPTGLQPPGCKDHGCSSGSPFRDPAGSSVIRSGKGDRQEGPSFLRPPAVTVKKLQKWMYKGRLLSLGMKGRARGTAPKVTGTQAASPNVGALKVRENRVLSVPPDQRITLTDLFENAYGSSMKGRELEELKDNIEFRGHKPLNSITVSKKRNWLYQSTLRPLNLEEENKKCQDRSHLSISPVSLPKHQLSQSFLKSSKEYCTYVVCNATNSSLSKNCALDFNEENDADDEGEIWYNPIPEDDDLGISSALSFGEADSAVLKLPAVNLSMLSGSDLMKAERHTEDSLCSSEHAGDIQTTRSNGMNPIHPAHSTEFVQQYKQKLGHKTQEGIMVEDSPMLKSPFAGSGILAATNSTELGIMEPSSPNPSPVKKGSSINWSLPDKIKSPRTVRKLSMKMKKLPEFSRKLSVKGTLNYINSPDNTPSLSKYNCREVHHTDILPSGNTTTAAKRNVISRYHLDTSVSSQQSYQKKNSMSSKYSCKGGYLSDGDSPELTTKASKHGSENKFGKGKEIISNSCSKNEIDIDAFRHYSFSDQPKCSQYISGLMSVHFYGAEDLKPPRIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHGTVVLPTLFRVTKTHQLAVKLEPRGLIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQLWPVQRLTVKKSTDNLFPEQKSSLNYLRQKKERPHMLNLSGTDSSGVLRPRQNRLDSPLSNRYAGDWSSCGENYFLNTKENLNDVDYDDVPSEDRKIGENYSKMDGPEVMIEQPIPMSKECTFQTYLTMQTVESTVDRKNNLKDLQESIDTLIGNLERELNKNKLNMSF
Protein: Small ribosomal subunit protein mL104 (rPPR9) (PPR PROTEIN LOCALIZED TO THE NUCLEUS AND MITOCHONDRIA 1) (Pentatricopeptide repeat-containing protein PNM1, mitochondrial) (Q9FME4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: RNA-binding protein that functions in both mitochondrion and nucleus. In mitochondrion, it is associated with polysomes and may play a role in translation. Required during embryogenesis. In nucleus, might be involved in the regulation of its own gene expression.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:21297037, ECO:0000305|PubMed:25732537}. Nucleus {ECO:0000269|PubMed:21297037}. Note=Can localize to both mitochondrion and nucleus.
Interaction partners:
- Transcription factor TCP8
- Large ribosomal subunit protein mL101
- Uncharacterized protein
- Large ribosomal subunit protein uL11m
- At1g64880
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein mS80
- Large ribosomal subunit protein bL21m
- Small ribosomal subunit protein uS2m
- Pentatricopeptide repeat-containing protein At1g10270
Sequence:
MPPSLPSLQLRRLLLRSFISSSSVNTLQSQPRIISSKPLFSPLPPSRSSIFSTFPSRFFSSETNAESESLDSNEIALSFSKELTGNPDAESQTISQRFNLSFSHITPNPDLILQTLNLSPEAGRAALGFNEWLDSNSNFSHTDETVSFFVDYFGRRKDFKGMLEIISKYKGIAGGKTLESAIDRLVRAGRPKQVTDFFEKMENDYGLKRDKESLTLVVKKLCEKGHASIAEKMVKNTANEIFPDENICDLLISGWCIAEKLDEATRLAGEMSRGGFEIGTKAYNMMLDCVCKLCRKKDPFKLQPEVEKVLLEMEFRGVPRNTETFNVLINNLCKIRRTEEAMTLFGRMGEWGCQPDAETYLVLIRSLYQAARIGEGDEMIDKMKSAGYGELLNKKEYYGFLKILCGIERLEHAMSVFKSMKANGCKPGIKTYDLLMGKMCANNQLTRANGLYKEAAKKGIAVSPKEYRVDPRFMKKKTKEVDSNVKKRETLPEKTARKKKRLKQINMSFVKKPHNKMRRRM
Protein: Aldo-keto reductase family 4 member C8 (EC 1.1.1.-) (O80944)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Oxidoreductase acting on a broad range of substrates: reduces ketosteroids, aromatic aldehydes, ketones, sugars and other aliphatic aldehydes, and oxidizes hydroxysteroids. May function as detoxifiying enzyme by reducing a range of toxic aldehydes and ketones produced during stress.
Interaction partners:
- Probable aldo-keto reductase 5
- Probable aldo-keto reductase 1
- ARP protein
- TRAF-like family protein
- Gb|AAF32477.1
- At2g27680/F15K20.22
- Uncharacterized protein At1g23150
- Non-specific lipid transfer protein GPI-anchored 14
- Probable inactive poly [ADP-ribose] polymerase SRO3
- BTB/POZ domain-containing protein At2g30600
Sequence:
MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESLMPTPEMLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFTKFSNIPQEKFCRATEFAHETHGFYKTIEELWDGEI
Protein: Large ribosomal subunit protein mL46 (39S ribosomal protein L46, mitochondrial) (L46mt) (MRP-L46) (P2ECSL) (Q9H2W6)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042}.
Interaction partners:
- Mitochondrial ribosomal protein L40
- Large ribosomal subunit protein uL16m
- Large ribosomal subunit protein bL27m
- Small ribosomal subunit protein uS7m
- Large ribosomal subunit protein uL29m
- Small ribosomal subunit protein uS15m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein mL44
- Large ribosomal subunit protein uL4m
- Small ribosomal subunit protein uS11m
Sequence:
MAAPVRRTLLGVAGGWRRFERLWAGSLSSRSLALAAAPSSNGSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIEIERSLYSDHELRALDENQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQFKLGARITEADEKNDRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEWQPGETLRGTAERTLATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTGDFSQAGNKGHHVWVTKDELGDYLKPKYLAQVRRFVSDL
Protein: Chromosome 7 open reading frame 11 (cDNA FLJ76008) (A4D1W6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQRQNFRPPTPPYPGPGGGGWGSGSSFRGTPGGGGPRPPSPRDGYGSPHHTPPYGPRSRPYGSSHSPRHGGSFPGGRFGSPSPGGYPGSYSRSPAGSQQQFGYSPGQQQTHPQGSPRTSTPFGSGRVREKRMSNELENYFKPSMLEDPWAGLEPVSVVDISQQYSNTQTFTGKKGRYFC
Protein: (+)-copalyl diphosphate synthase 3, chloroplastic (MvCPS3) (EC 5.5.1.12) (A0A075FA51)
Organism: Marrubium vulgare (White horehound)
Function: Involved in the biosynthesis of labdane-type diterpenoid including marrubiin and other labdane-related furanoid diterpenoids with potential applications as anti-diabetics, analgesics or vasorelaxants (Probable). Terpene synthase that produces (+)-copalyl diphosphate ((+)-CPP) from geranylgeranyl diphosphate (GGPP).
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MGSLSTLNLIKTCVTLASSEKLNQPSQCYTISTCMKSSNNPPFNYYQINGRKKMSTAIDSSVNAPPEQKYNSTALEHDTEIIEIEDHIECIRRLLRTAGDGRISVSPYDTAWIALIKDLDGHDSPQFPSSMEWVADNQLPDGSWGDEHFVCVYDRLVNTIACVVALRSWNVHAHKCEKGIKYIKENVHKLEDANEEHMTCGFEVVFPALLQRAQSMGIKGIPYNAPVIEEIYNSREKKLKRIPMEVVHKVATSLLFSLEGLENLEWEKLLKLQSPDGSFLTSPSSTAFAFIHTKDRKCFNFINNIVHTFKGGAPHTYPVDIFGRLWAVDRLQRLGISRFFESEIAEFLSHVHRFWSDEAGVFSGRESVFCDIDDTSMGLRLLRMHGYHVDPNVLKNFKQSDKFSCYGGQMMECSSPIYNLYRASQLQFPGEEILEEANKFAYKFLQEKLESNQILDKWLISNHLSDEIKVGLEMPWYATLPRVETSYYIHHYGGGDDVWIGKTLYRMPEISNDTYRELARLDFRRCQAQHQLEWIYMQRWYESCRMQEFGISRKEVLRAYFLASGTIFEVERAKERVAWARSQIISHMIKSFFNKETTSSDQKQALLTELLFGNISASETEKRELDGVVVATLRQFLEGFDIGTRHQVKAAWDVWLRKVEQGEAHGGADAELCTTTLNTCANQHLSSHPDYNTLSKLTNKICHKLSQIQHQKEMKGGIKAKCSINNKEVDIEMQWLVKLVLEKSGLNRKAKQAFLSIAKTYYYRAYYADQTMDAHIFKVLFEPVV
Protein: Mitogen-activated protein kinase kinase 5 (AtMAP2Kalpha) (AtMEK5) (AtMKK5) (MAP kinase kinase 5) (EC 2.7.12.2) (Q8RXG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitogen-activated protein kinase kinase (MAPKK) which regulates abscisic acid (ABA) responses in a MAPKKK20-MKK5-MPK6 cascade involved in root growth (e.g. root cell division and elongation) and stomatal response, probably via MAPK6 activation by protein phosphorylation. Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the morphology of plant organs. MKK4 and MKK5 participate in the regulation of floral organ abscission. Target of the Pseudomonas syringae type III effector HopF2, that inhibits the activation of the downstream MPK6 and PAMP-triggered immunity. Plays a critical role in high light stress tolerance by the mediation of the Cu/Zn SODs CSD1 and CSD2 gene expression. Phosphorylates BZR1 in vitro.
Interaction partners:
- Mitogen-activated protein kinase 6
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase kinase kinase 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase kinase kinase YODA
- Mitogen-activated protein kinase kinase kinase ANP1
- Mitogen-activated protein kinase kinase kinase 2
- Mitogen-activated protein kinase kinase 4
- Small ribosomal subunit protein RACK1y
- Small ribosomal subunit protein RACK1x
Sequence:
MKPIQSPSGVASPMKNRLRKRPDLSLPLPHRDVALAVPLPLPPPSSSSSAPASSSAISTNISAAKSLSELERVNRIGSGAGGTVYKVIHTPTSRPFALKVIYGNHEDTVRRQICREIEILRSVDHPNVVKCHDMFDHNGEIQVLLEFMDQGSLEGAHIWQEQELADLSRQILSGLAYLHRRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNHGRYDGYAGDVWSLGVSILEFYLGRFPFAVSRQGDWASLMCAICMSQPPEAPATASQEFRHFVSCCLQSDPPKRWSAQQLLQHPFILKATGGPNLRQMLPPPRPLPSAS
Protein: Unc-50 related protein homolog (Q38DR2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAQGGFTLSSRWVSRLPEFARRAFQYDQMELDSALAQMYSLCVKPSLISKMSKARKMTKNHYHRDDPAFIVLQIFSLVLTVAAYGLALRGGLLQILYNTLYSVLLGYFAAGGAIATVTWLFANHFLAASSQPHESGWEVDWRYSFDVHCNGYFPYFIWTKVIQFVLLPIVLHNSCVPRAIGNCLHTVGLVMYAYVVFLGYLELPMLAQQQRLMYPVPLVVVFMLLVTLFTSWNVSYWSLCQTWCS
Protein: Phosphodiesterase (EC 3.1.4.-) (G8JYF6)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGDRSGVGGEEGEKSVLGASAHSQAGRRQQHTPAARRGAQRAPAATAAAASRPVFAMRWCCGGSYSENGGGGGGSRGAPPTPLLTVAATSSSTAHDTFGPMQVKMLKTAVIVTEGTGESVLLDSLRASGWICTVSFPTQATSDVESICPLAVFIDLRVPHPSQIAKDVSSVSTEEVLIVSIAEKHISEKRRRALAQSNIIHHVTWNTRDVVLFDYVGRLANRIRALPALFAVLDETDQAVEICDEQRVVQYVNRAYENVTGCIRSEVIGQPESEMRRKSLPRARGEEERRRSCDWKFIRVPFANNSQFVYMKRSNTTGDTAAIFRDVSLKSLKSQTGGIEAPISEVLTMLRDVSARVDGEPAQTIKDAMKVLSSHELYAPSINRFRDADRIATQYYDGLIRLHHPARQRKRSVVDAHREKRGSHGERRRVSADVKNALENDNCWKFDILHLEKVSDHHALSQVGMKVFERWKVCDVLGCSDDLLHRWILSIEAHYHAGNTYHNATHAADVLQATSFFLDSPSVAVHVNESHAVAALLAAAVHDLDHPGRGNAYLINTRQSLAILYNDNSILENHHIALAFQLTLQHNANVNIFSSLSREEFIQMRHAMVEMVLATDISRHFEYLAKFNKMHVTDVPEEQRDTNSLTICDMLVKCADISNPAREWGLCQRWAHRIVEEYFEQVRRSGEGGNCRFAGNA
Protein: Tetraspanin (B1AKP1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
Interaction partners:
Sequence:
MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSAIRHVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI
Protein: Ezrin (Ezrin b isoform X1) (Villin 2 isoform X1) (Q5TZG5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}.
Interaction partners:
- Actin alpha 1, skeletal muscle b.
- Na
- Moesin a
- Sodium/hydrogen exchanger
- CD44 antigen
- Actin, cytoplasmic 1
- Actin, cytoplasmic 2
- Protein kinase C
- Protein kinase C
- Tight junction protein 1a
Sequence:
MPKPVNVRVTTMDAELEFAVQPSTTGKQLFDQVVKTIGLREIWYFGLQYMDSKGYLTWLKLDKKVSSQDVKKENPLQFKFRAKFFPEDVADELIQDITQKLFFMQVKDGILSDEIYCPPETAVLLASYSVQAKFGDFSKELHRPGYLTSERLLPQRVLDQHKLSREQWEERIQVWHEEHRGMLREDAMLEYLKIAQDLEMYGVNYFDIKNKKGTELWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKQQKQMERAQLENEKKRREAIEREKEQMEREKKELMMQLYQFEERTKKVENELQEQMQRAMQLQHERRLADEEAARLEAERQAALLAKEELARQAQDQLKSQEQLAAELAEYTAKISLLEEAKKRKEEEAQTWQNKAQLAQDDLIKTRQELHNVMTAPPLPPPPPAYDHDENDLDDGEESNGSYTADLQTGGFNDHRLEEERITEAEKNERVQKQLLALTSELAQARDDTKKTQNDLLHTENVRAGRDKYKTLRQIRQGNTKQRIDEFEAL