wanglab/gogpt-training-data huggingface dataset:
Protein: EG:56G7.1 protein (Mucin related 2B, isoform A) (Mucin related 2B, isoform C) (O76894)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Mucin 91C, isoform A
- GH06474p
- RE05851p
- IP19005p
- IP19013p
Sequence:
MTHCLWSTLLGLLSVLSTATSRSVRQLPSAYPPVLPTGYYGQPPYAYPPYGYGYQAPPPVYQPYYDNVFGVFKSYPGGGFPVRFDYNNRCSRNYIGIKPHPDQQQYYYVCKPDCVIFSKCRGLESFNASSGRCVQHVPQHRPDHRPPQCQKEGRFPHPHDCKVYYRCDKNRTQPWLFACPAGTIFSPVERKCLPGDQCPSTEISDSGSYIPQNCELKFPECAEEGTFRSPTDCALYYTCRLQESGTYLQTRFKCPGSNSFDLERKLCRPRSEVDCFDFVPGPVQVPYAPQPYYPPYPAAPPLYEEDDYDTGAREQQPALKSEKLQVAAEGFEKPSLNVVVLQTTTLEPSTAYHKYPAYPSYPSYEYSSHHRGKERAAENLELEKEGVPRKLKLSENIVIQPETPATAATTREPLNDINKYQYKRYTYGTDKNDVTEAPEIKSPLKGLHLSENIVILPETTTTTTTTTKPVVLTCPTISPPDTTPKPSTTTAVTKSTPKISSTEQHSTTTAKTTTTKRPTTVTEKTSSATEKPRTTVVTTTTQKRSTTTHNTSPDTKTTIRSTTLSPKTTTTPSTTTPSTTTPSTTTPSTTTPSTTTPSTTTPSTTTTVKVSTHRPRTTSQKTTTASTTTKKTTTSPKTTKTTDIPTSTTSKLSTTTQKTTTTTHKFTAATTSTEKPKTTTEKTSTVSTTTKKSTESSPKPTSSTGKPTTTPKPSTRTTPTTTKVTTTTQITTTTPLRSSTETTSTQPPTTTTPQPTTTTTLTVTPKTSTTTTTTEKPITSSPKPTTTTQKTTSTAPNTTKVAITTQKETTPTQSTSTTIFTRKTTTNNPEPTSTEKPITSTTPKPSTTTPKTSTVASSTEKTTISSPKPTTEKSTENPTTNSVKTSALTSSTQRATSTTSEPTKTTQNITTTTPKPTTLKTSTQEATTSTQKVSTVTITTKKATESSPLTTLSTEEPNTTPKPLRTTTPTTTSVTATTRITTTTISESSTETTSTQKPKSTTPTSTTRTTPKVTTVIVSTQNPTTTTSKTSTVTITTPNPSPSTQRPTTTTRQPTSITASTTSIGTTRIPTTTNPQNSTSSTDLTTVTRPPCPDPDSTSDKNTNTACTQELQQVNLLELQSPQKQEQFTHTRTHTALTGSRNTLGGQEVPDYMDDAPSSAEAESGQATTAKAPTMSTLAAAHLLQKLFHIISTTPPSREHAPTQRPSSQPSSSQRSRGVTIAQMARHNLATSKPFIAHSLRLSIQQLASTQKRSIPPKTLVTHNTTKEPEDSEYYDSETSEQYTDEDNEVLDKTQPRAMSSTTVAAVLPAVPSTTTEREPQKTSSSPSPTKATSSTTTQPIETTTGDLEYDSSGSSDYVNDANDISSGVVNSLEARKNFLLSLLKQRLTQIERTEAKKPATSTSTTTDAPKTSSSSTSPASTTSESTSPVTSSTARSSLTASKHLGPEALSRQKSLTPQSAEYYDEDDDYMEDEPVGSSDAEKKEHGTVLISEKQAAATAKRHIAPPSAQPLRQAMLNILATRSEENKVDLKTTSDGLQFRRFESSQIPTEGPPNRASIVVAEALSRRLADNVGEHLPGPTVPHTSDAKAISSVSQTTIRSRESQTKSSSQTPPSISTETPATQAIQNHRTDEATQSTLEIVTQTTPKSAPPATAVPVAVRQEVLSVNSRPWLLAARNQTVHLTPISSIAARAPSNPVSHANRSINPLVSSPEDHSTEKVPQLIVKVYEPIDLKIVFCPKSCDQDHDHKFDPADNIKTSNCTGGCDEEEERIHKHVDIQWKPLELTDIAGFRNAV
Protein: Subtilase SubB (Subtilase cytotoxin SubB) (Subtilase cytotoxin, subunit B) (Q3ZTX8)
Organism: Escherichia coli
Interaction partners:
Sequence:
MTIKRFFVCAGIMGCLSLNPAMAEWTGDARDGMFSGVVITQFHTGQIDNKPYFCIEGKQSAGSSISACSMKNSSVWGASFSTLYNQALYFYTTGQPVRIYYEPGVWTYPPFVKALTSNALVGLSTCTTSTECFGPDRKKNS
Protein: Regulator of G protein signaling 3 (Q5VXC0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDSKKLHPFGSLQQEMGPVNSTNATQDRSFTSPGQTLIG
Protein: Vacuolar protein sorting 35 variant (Q53FR4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
Sequence:
MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLISNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL
Protein: Palmdelphin (Q4KM62)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16323283}. Cell projection, dendrite {ECO:0000269|PubMed:16323283}. Cell projection, dendritic spine {ECO:0000269|PubMed:16323283}.
Interaction partners:
Sequence:
MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEEKLKHQHLKKKALREKWLLDGIGSGKEHDEMKKQNQQDQHQTQVLEQSILRLEKEIQDLEKAELQISANEEVILKKLKSIERTTEDIIRSVKVEKEEIPEESIEDIYANIPDLPSSYIPSRLRKERNEESDDEQNRKALYAMEIKVEKDLKTGESVVLSSIPLPSDDFKSTGIKVYEDRQKSVYAVSSNQNTAYNGTDGLAPVEVEDLLRQASERNSKSPTEYHEPVYANPFCRPMTPQRERVISPGPNSQERMVMMKANGLDHHESESVHGMTDGLSERRSNGLAHTSPTRPTPQPRSKVQQVEEMVHTQQKRMPSPWEESSIRQNEYEVSPRTELSPSRASPGKSGPQCSSPICQEEADVRYNIVHSLPPDVDDTEPVTMIFMGYQQADENEEEKKLLTGYDGVIHAELVVIDDEAEDDEGQAEKPSYHPVAPCSQVYQPAKPTPLPRKRSEVSPHENTNHKSPHKNSISLKEQEERLGSPARHSPLGVPGAGDGTEDPSLTALRIRMAKLGKKVI
Protein: Zinc finger protein 503 (Q96F45)
Organism: Homo sapiens (Human)
Function: May function as a transcriptional repressor.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ
Protein: SLAIN motif family member 2 (D6RIF6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSYTSPYSPNASSPYSSGFNSPSSTPVRPPIVKQLILPGNSGNLKSSDRNPPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAATTSRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDNMHHAVYPAVNRFSPSPRNSPRPSPKQSPRNSPRSRSPARGIEYSRVSPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRTSNTQVDSVKSSRSDSNFQVPNGGIPRMQPQASATSQRLKNLPRTSLKAKQLLQTSSTKRVPSPGKFRSPAAPSPLALRQPVKAFSNHGSGSPGSQEITQLTQTTSSPGPPMVQSTVSANPPSNINSATLTRPAGTTAMRSGLPRPSAPSAGGIPVPRSKLAQPVRRSLPAPKTYGSMKDDSWKDGCY
Protein: RXRB (Retinoid X receptor beta isoform 2) (A0A0S2Z570)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
Protein: Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12) (P56730)
Organism: Homo sapiens (Human)
Function: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
Subcellular location: Secreted.
Interaction partners:
- Coiled-coil and C2 domain-containing protein 1A
- Protein cereblon
- Agrin
- Carbonic anhydrase 4
Sequence:
MTLARFVLALMLGALPEVVGFDSVLNDSLHHSHRHSPPAGPHYPYYLPTQQRPPRTRPPPPLPRFPRPPRALPAQRPHALQAGHTPRPHPWGCPAGEPWVSVTDFGAPCLRWAEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTKL
Protein: Troponin I, cardiac muscle (Cardiac troponin I) (P48787)
Organism: Mus musculus (Mouse)
Function: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Interaction partners:
- Troponin T, cardiac muscle
- Troponin C, slow skeletal and cardiac muscles
- Actin, alpha cardiac muscle 1
- Tropomyosin alpha-1 chain
- Myosin-6
- Troponin T, slow skeletal muscle
- Myosin-binding protein C, cardiac-type
- Tropomyosin beta chain
- Troponin C, skeletal muscle
- Tropomyosin alpha-3 chain
Sequence:
MADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSKISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLRTRCQPLELDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKKEDIEKENREVGDWRKNIDALSGMEGRKKKFEG
Protein: At1g02360 (Chitinase family protein) (Putative chitinase) (Q9FZ25)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAQQHSFLLLCFFLSISYLLSSAQTEATSIERLVPRDLYNKIFIHKDNTACPANGFYTYESFVQATRRFPRFGSVGSPVTQRLEVAAFLAQISHETTGGWATAPDGPYAWGLCFKEEVSPQSTYCDSSDTQWPCFPNKTYQGRGPIQLSWNYNYGPAGRALGFDGLRNPETVSNNSVIAFQTALWFWMTPQSPKPSCHDVMIGKYRPTAADLAANRTGGFGLTTNIINGGLECGIPGDGRVNDRIGFFQRYTGLFKVATGPNLDCENQRPYA
Protein: Pawn, isoform B (A1Z6W9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRRKPQNLTHSIPSSRAGDRGGGGGGVGRGTSRPSAISNNRRPRDHRHLMAMVVSTLPLALLLLLVQTTAGQHESVSQISPKSSSHRSPDRQRIESTMADSVNGLAEGQSSPLDVNDNETRAERVERSASPILHDRQPIGPNDVHFPEDLEKDVSAGRYFHYNIKPTGTFDNQDEQPERTHQGIRAGKTLSQGGSSSEQSFLGRGDLRPLVSGSPIRPSPSNTATSATAASATQAPHSPRQNGNPDIQDIITGIVKLLNGNVNVHANTQGIRRPSASRINNRGPPRISEAQNLPIDYEAQKPGTSMRPPPYPFDRPERPFITGVPIPEQIVPVRPGFVSNRPPWYRNKPRPPIATSVGGNRRPLPQYKPLPAPPVQAPLQPQDPLDRKNEQEKEQNHQEQPQPTDDVVLPTDTTYDSEFSNEDANAQYIEVSDQDTDATGGEVEDELQPPPPPPSTTNNPPTTPTNPSKKKHKPKPGSEKKKLPEESPQDEGFSTIIETSSVVHTVMGMSSTYVPMSMDSSESLGLDPSTEEVIFMTANRTPTLEPSVTSSLGTSSSSNPASAIQPTSSKEHTKTTTTTTTTTSSSTSTTTSTTTPPSTESVSPNSSNANTNATPPAPYHPRPGIVLDDPEFKPGGRPRPPVQRPPAQQTLPLPAVQPTRQHLPPGYGEIFDVTLSAIQGPGPKGSGSQQTINIKPYGSYAAGGGQGDIIVSASGDDGFVSIDGKRTYINLFGDPTDPPAGATTPATRLPQLPGSGSGSGSGSGTGSGGASTPGVGVSSGGGGGSGSSISPAAPANAVTQSSGGYVVPETEVVDLQGHSKPQGGAPTTNAGPTRPHYRQRPTQPPVRIDTCIVGDDSTCDQAQHERCKTDNGVSSCHCRPGYSRRKHREPCRRVISFHLGMRVDRIYEHRIVWDTKLMDKHSEPFGQLSYESIRALDSAMSMTPYSDEFMEAKVNNIYRGDPNLGGSGVYVNMTIKLDESVETLRPNLRSDVQKHLLGVLHRRNNNIGNSVLYVSSPEGAVSALQDLDECQSPELNDCHSGASCSNTWGSFRCACEAGLRDPWADQPARSGRECQACADSVCNNHGTCSYAEDGAQLCTCDSSHYGAQCEIDGEVLGVAIGASVAAIIIIVLTLVCLIMWSRRWQREQKNAMGSPVFGYMNTAPLKSAGLPQAGYQVTLEDRMRWAQIADVMAQTNHYGAEPIGPTRPSSAMFAYPNLGAMGMGTLGGMSLQSTMQMHPSATLAPPVPLPRLGLGPRSNGMRTLENSSSSEEEDRADLLGRNFQVPRPKSRSNGSIANQSGIYYDVDYEPSGNGIGNSSVDHLYGSQNQSVTHSSGHSHIPGPQGIPMSTYTSGRAPSSYYMK
Protein: Histone H2B.9 (HTB10) (Q9LZ45)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
Interaction partners:
- Histone H4
- E3 ubiquitin-protein ligase BRE1-like 1
- E3 ubiquitin-protein ligase BRE1-like 2
- Histone H3.1
- Histone H3.3
- Histone H3-like 5
- Histone H3-like centromeric protein CENH3
- Histone H3-like 3
- Histone H3-like 2
- Histone H3-like 4
Sequence:
MAPKAEKKPAEKAPAPKAEKKIAKEGGTSEIVKKKKKTKKSTETYKIYIFKVLKQVHPDIGISGKAMGIMNSFINDIFEKLAQESSRLARYNKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS
Protein: Probable anti-sigma-M factor YhdK (O07580)
Organism: Bacillus subtilis (strain 168)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable anti-sigma-M factor YhdL
- ECF RNA polymerase sigma factor SigM
Sequence:
MELVRIFKEHNVFGWISVGTAVLSLLLLNLAIISNVTFYSYQMLPFAMAAVPFGVVELFIKRGRTGPGLLGVILNLFVIICVYTIVSVDTNLQFGF
Protein: Zydeco, isoform F (Q5LJX8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Golgi to ER traffic protein 4 homolog
Sequence:
MMRIRNMKSSISHILLFCYINCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKCAKGGVKQARSRSRSSNCSIHTKNSNEKEPELVENRICQNMANIQLNGGLNKEQAKATSTSGAGTTAISITTSTMTTTLSTTHSAGGGGGAVGLCSGPGAIVQMAPLDDAEAESHVAVAAADEGRKEEGYSLLSYPKDKSCFAQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVPWLIKAVFFPIQPGQNYVAINSAGLEYSAITLLSTLFLLYLTFSTNKFKLDKKVGTACLVMYLVFMVFASLIELNVFFRVNLPTCGRS
Protein: Glycerol-3-phosphate acyltransferase 9 (AtGPAT9) (EC 2.3.1.15) (Q8GWG0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protein. Required for male and female gametophytes development. Exhibits sn-1 acyltransferase activity with high specificity for acyl-coenzyme A, thus triggering storage lipid biosynthesis and playing an important role in the Kennedy pathway of glycerolipid biosynthesis. Catalyzes triacylglycerol (TAG) accumulation involved in membrane lipid and oil biosynthesis, especially in seeds. Contributes also to the biosynthesis of both polar lipids and TAG in developing leaves, as well as lipid droplet production in developing pollen grains. Seems to not contribute to surface lipid biosynthesis (e.g. waxes and cutin).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19539490}; Multi-pass membrane protein {ECO:0000269|PubMed:19539490}.
Interaction partners:
- 1-acyl-sn-glycerol-3-phosphate acyltransferase 2
- 1-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic
- Glycerol-3-phosphate acyltransferase 1
- Probable glycerol-3-phosphate acyltransferase 3
- Probable glycerol-3-phosphate acyltransferase 8
- Glycerol-3-phosphate 2-O-acyltransferase 6
- Glycerol-3-phosphate acyltransferase 7
- Glycerol-3-phosphate 2-O-acyltransferase 4
- Probable glycerol-3-phosphate acyltransferase 2
- Lysophospholipid acyltransferase 1
Sequence:
MSSTAGRLVTSKSELDLDHPNIEDYLPSGSSINEPRGKLSLRDLLDISPTLTEAAGAIVDDSFTRCFKSNPPEPWNWNIYLFPLYCFGVVVRYCILFPLRCFTLAFGWIIFLSLFIPVNALLKGQDRLRKKIERVLVEMICSFFVASWTGVVKYHGPRPSIRPKQVYVANHTSMIDFIVLEQMTAFAVIMQKHPGWVGLLQSTILESVGCIWFNRSEAKDREIVAKKLRDHVQGADSNPLLIFPEGTCVNNNYTVMFKKGAFELDCTVCPIAIKYNKIFVDAFWNSRKQSFTMHLLQLMTSWAVVCEVWYLEPQTIRPGETGIEFAERVRDMISLRAGLKKVPWDGYLKYSRPSPKHSERKQQSFAESILARLEEK
Protein: Gamma-synuclein (Synoretin) (SR) (Q9NZ50)
Organism: Bos taurus (Bovine)
Function: Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11746666}. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
Interaction partners:
- Beta-synuclein
Sequence:
MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKEGVVQSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEVENIAVTSGVVHKEALKQPVPSQEDEAAKAEEQVAEETKSGGD
Protein: DNA repair protein RAD33 (Q04231)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleotide excision repair (NER) of damaged DNA. Required for the repair of RNA polymerase I-transcribed rDNA and RNA polymerase II-transcribed DNA regions. May have a role in stabilizing the DNA repair proteins RAD4 and RAD34.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- DNA repair protein RAD4
- UV excision repair protein RAD23
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2
- DNA repair protein RAD34
- General transcription and DNA repair factor IIH subunit SSL1
- General transcription and DNA repair factor IIH helicase subunit XPD/RAD3
- General transcription and DNA repair factor IIH subunit TFB1
- General transcription and DNA repair factor IIH subunit TFB5
- General transcription and DNA repair factor IIH subunit TFB4
- General transcription and DNA repair factor IIH subunit TFB2
Sequence:
MSKSTNVSYERVELFENPKVPIEVEDEILEKYAESSLDHDMTVNELPRFFKDLQLEPTIWKLVRNEDVIIEGTDVIDFTKLVRCTCQLLILMNNLTVIDDLWSMLIRNCGRDVDFPQVALRDHVLSVKDLQKISNLIGADQSSGTIEMISCATDGKRLFMTYLDFGCVLGKLGYLKM
Protein: Spermatogenesis associated glutamate (E)-rich protein 4D (L7N261)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKLMTLQQESKEVQADWAIIHQCLVELNLSGKDEQEENSNLETPEYQVSETARELGLATAEEDSILQNELPGQEAPAEHHLQHLQSSSDESSSI
Protein: Proteasome subunit alpha type-4-like (Q9VA12)
Organism: Drosophila melanogaster (Fruit fly)
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:12421421}.
Interaction partners:
- Proteasome subunit alpha type-5
- Proteasome subunit beta type-1
- Proteasome subunit beta type-3
- Proteasome subunit alpha type-3
- Proteasome subunit alpha type-2
- Proteasome subunit beta type-4
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit alpha type-6
Sequence:
MARFFDSRTTIFSPEGRLYQVEYAMEAASQSGTCVGLLAKNGVLLATERSVDKLMDTSIPVPRISWLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQLVTNLCDIKQAYTQYGGKRPFGVSFLYMGWDCRFGFQLYQSDPSGNYSGWKATCIGRKSGAAMEMLQKELFSKGYVSPSVEEAKDVAIKVMGMTLGRDSLTPEKLEIAFVQRYGNTTVFHILEKNEIHRLIERNNNLKRRVGS
Protein: Pentacotripeptide-repeat region of PRORP domain-containing protein (Q57YK5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Small ribosomal subunit protein mS29
- 30S Ribosomal protein S17, putative
- Methyltransferase
- Translation initiation factor IF-2
- Acyl carrier protein
- Dehydrogenase-like protein
- [acyl-carrier-protein] S-malonyltransferase
- Mitochondrial glycoprotein-like protein
- DNA photolyase, putative
- Potassium voltage-gated channel, putative
Sequence:
MHPRLSGQGVFPRYGGGWMHQFGHVYALQQELLNAEANNWFRAMELWHTARHEGVAMNVSHYTNILRQCVPPTAWEASLMVLKQMRRENIRPDVVGVGCALAACADANRSEEVEKVFSCFSGKLKLDSICYLALIKAKMSRGGYAEALAVGREQDADGVPFLPHTYTHLLEAAEVADDGEMALELARRMSSEQWPVSDRGREALKKLSTRHHWEEVAEYKQFVAVEDHKLSLPPTLPRG
Protein: BCL2 modifying factor 1 (Bmf1) (Q0GKC7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDEDEDDVFRKGLQHWPPPHLQIKQTELAGRPAGSRNGMLLCRHLQQHGHFLYGNAELLVLAASSRAQPPDVVLRQNVSPMERPEPRPAQSVETLIGQKLQLIGDQFYQEHIMHHQRPQDPLWRRVATAVLTLLFGARENRR
Protein: DAAM2 protein (Q6DCB0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPISNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKVPSLTPLATSQGSWHGVALAALACSCIHLMFITCQPCSRCWRNNSE
Protein: Transcription factor MYB86 (Myb homolog 4) (AtMyb4) (Myb-related protein 86) (AtMYB86) (Q8LPH6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Trans-cinnamate 4-monooxygenase
- Transcription factor EGL1
- Transcription factor GLABRA 3
- Protein TRANSPARENT TESTA GLABRA 1
- Dihydroflavonol 4-reductase
- Naringenin,2-oxoglutarate 3-dioxygenase
- NAC domain-containing protein 12
- Flavonoid 3'-monooxygenase
- Flavonol synthase/flavanone 3-hydroxylase
- Transcription factor TT8
Sequence:
MGRHSCCFKQKLRKGLWSPEEDEKLLNYITRHGHGCWSSVPKLAGLQRCGKSCRLRWINYLRPDLKRGAFSQDEESLIIELHAALGNRWSQIATRLPGRTDNEIKNFWNSCLKKKLRRKGIDPTTHKPLITNELQSLNVIDQKLTSSEVVKSTGSINNLHDQSMVVSSQQGPWWFPANTTTTNQNSAFCFSSSNTTTVSDQIVSLISSMSTSSSPTPMTSNFSPAPNNWEQLNYCNTVPSQSNSIYSAFFGNQYTEASQTMNNNNPLVDQHHHHQDMKSWASEILHYTEHNQSSETVIEAEVKPDIANYYWRSASSSSSPNQEAATLLHDANVEVYGKNLQKLNNMVFDQSL
Protein: Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (mDTX2) (RING-type E3 ubiquitin transferase DTX2) (Q8R3P2)
Organism: Mus musculus (Mouse)
Function: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q86UW9}. Nucleus {ECO:0000250|UniProtKB:Q86UW9}. Note=Predominantly cytoplasmic. Partially nuclear. {ECO:0000250|UniProtKB:Q86UW9}.
Interaction partners:
- Neurogenic locus notch homolog protein 2
- Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 4
- E3 ubiquitin-protein ligase DTX1
Sequence:
MAMAPSSSLPQVYPSHVVVAVWEWQDGLGIWHPYSATVCSFIEQHFVRQRGQHFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQNTGTMRSVRRHLFSQNSAPGQGIVWEWLGDDGSWVAYEARICDYLEQQVARGIQVVDLAPLGYNYTVNYATLTQTNKTSSFCRSVRRQVGPVYPVTSDIAVPRQMGLICFCQQCLHGSGTGPVSGRYRHSMTNLPAYPAPQAPHRTTTVSGAHQAFAPYNKPSLSGARSAPRLNTTNPWAAAPPVAGNQSLFHSSLSHLGPQLLPSGPSTSSGASASFPSGPSSSSPGSAPTTVPVQMPKASRVQQALAGMTSVLSAIGLPVCLSRAPRPTGPPASRPASKSHSSVKRLRKMSVKEGAPKPEPEQVIRKYTEELKVAPEEDCIICMEKLAVASGYSDMTDSKALGPMVVGRLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPWGKMEVFRFQMSLPGHEDCGTILIVYNIPHGIQGPEHPSPGKPFTARGFPRQCYLPDSPQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ