wanglab/gogpt-training-data huggingface dataset:
Protein: Probable protein phosphatase 2C 10 (AtPP2C10) (EC 3.1.3.16) (Q9S9Z7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Phosphatidylglycerophosphate phosphatase PTPMT2
- acid phosphatase
- Metal ion-binding protein
- Mitochondrial carrier protein MTM1
- Dual specificity protein phosphatase PHS1
- Inositol diphosphatase DSP4
- Inositol diphosphatase DSP3
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
- Inositol diphosphatase DSP2
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN2B
Sequence:
MAKLCCFGSSDYDLVVGRASTSSGKGRNNDGEIKFGYSLVKGKANHPMEDYHVSKFVKIDGNELGLFAIYDGHLGERVPAYLQKHLFSNILKEEQFRYDPQRSIIAAYEKTDQAILSHSSDLGRGGSTAVTAILMNGRRLWVANVGDSRAVLSQGGQAIQMTIDHEPHTERLSIEGKGGFVSNMPGDVPRVNGQLAVSRAFGDKSLKTHLRSDPDVKDSSIDDHTDVLVLASDGLWKVMANQEAIDIARRIKDPLKAAKELTTEALRRDSKDDISCIVVRLR
Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1) (P08487)
Organism: Bos taurus (Bovine)
Function: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Plays a role in actin reorganization and cell migration (By similarity).
Subcellular location: Cell projection, lamellipodium {ECO:0000250|UniProtKB:P19174}. Cell projection, ruffle {ECO:0000250|UniProtKB:P19174}. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. {ECO:0000250|UniProtKB:P19174}.
Interaction partners:
- Platelet-derived growth factor receptor beta
- Linker for activation of T cells
- Tyrosine-protein kinase
- Receptor protein-tyrosine kinase
- Proto-oncogene vav
- Lymphocyte cytosolic protein 2
- Fibroblast growth factor receptor
- Tyrosine-protein kinase
- Fibroblast growth factor receptor
- Protein kinase C alpha type
Sequence:
MAGAASPCANGCGPSAPSDAEVVHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIRGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRTSDITYGQFAQLYRSLMYSAQKTMDLPFLEASALRAGERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSIWNSQLDEVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASGSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAVRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFLAGGHCGYVLQPSVMRDEAFDPFDKSSLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEGLELASLLVKIDVFPAKQENGDLSPFGGASLRERSCDASGPLFHGRAREGSFEARYQQPFEDFRISQEHLADHFDGRDRRTPRRTRVNGDNRL
Protein: Transmembrane protein (Q583H2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFRNRFFIRLQSNKGVGHHKFPRRATHHAVSSAKLGKERFDLMESLRRDREEAERNRMLPWRSRLKKLQEYPWKFFIAFMVFWSWLGTYAVPYLKNMRPGELPTVWEGRPIPKELKERATPMPHFRRLSKGIDES
Protein: At4g02725 (Spindle pole body-associated protein) (Q6DBF6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Putative E3 ubiquitin-protein ligase XBAT35
- Agamous-like MADS-box protein AGL70
- Histone-lysine N-methyltransferase, H3 lysine-79 specific-like protein
- Serine/arginine-rich SC35-like splicing factor SCL30A
- Scarecrow-like protein 1
- Probable sodium/metabolite cotransporter BASS5, chloroplastic
- Serine/arginine-rich splicing factor SC35
Sequence:
MASLSMSAVSLSPFRPQTENLLSKLSFRTNLHSFNLKPIRISTKVRSFGGNRREPKDSRFVDEKGVVDDMEGFLDNLSLEYDSVWDTKPSWCQPWTIMLTGLSIVACSWVILHSVIVSSLAVGVIGAWWYIFLYSYPKSYSEMIAERRKRVADGFEDIYGKNKPS
Protein: Damage-inducible protein (Q7CRY3)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Interaction partners:
- Uncharacterized protein
- Error-prone DNA polymerase 1
- DNA polymerase IV 1
Sequence:
MQKRADQLLVVEELRERLERIGNGPERLHETLPFGVDAIDHHLPGGGLKLGCLHELSGGGNGAADGAAAALFAAGVAARLSGKVLWCVTRRDLFMPGLTQAGLSHNRLIIVECRDEKGVLDCFEEGLRCNGFGAVMGELSKLPMTASRRLQLAAETSGVTGIAIRRFRRPADAALFGEPTAAVTRWRISVRPSSPLPVPGVGRPRWFLELLRCRGGESAEFEVEACDAKGRLALPADMADGSFPASFGQGRAAG
Protein: Glycosyltransferase GtfE (EC 2.4.1.-) (Q9AFC6)
Organism: Amycolatopsis orientalis (Nocardia orientalis)
Function: D-glucosyltransferase that acts on the aglycone core, transferring D-glucose to the phenolic hydroxyl of OH-Phegly(4) to form a devancoaminyl-vancomycin (DVV) intermediate in the biosynthesis of glycopeptide antibiotic vancomycin. Also able to glycosylate A47934, an antibiotic with a teicoplanin-like heptapeptide, but lacking sugar residues.
Interaction partners:
- Glycosyl transferase
- Glycosyl transferase
Sequence:
MRVLLSTCGSRGDVEPLVALAVRLRARGAEVRMCAPPDCADRLAEVGVPHLPLGRSARPAAAGEAKPLTAEDMLRFTTETIAMQFDRIPAAAEGCDAVVTTGLLAAALGVRSVAEKLGIPYFYAFHCPSYVPSPYYAPPPPLGEPPAPEGTDIRALWERNNQSAFRRYGAPLKSQRAAIGLPPVEDIFEHGYTDHPWMAADQVLAPLQPTDLDAVQTGAWILPDERPLSPEMEAFLDAGTPPVYLGFGSLRAPADAAKVAIEAIRAHGRRVILSRGWADLVLPDDRDDCFATGEVNQQVLFRRVAAVIHHGGAGTTHVATRAGAPQILVPQIADQPYYAGRVAELGIGVAHDGPTPTFESLSAALTTALAPETRVRAEAVAGTVLTDGAAAAADLLFAAVGEEKPAVPA
Protein: ANKHD1 protein (Q8IWG5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDVNSSKYPSLLLHSQEEKTSTATSKTQTRLEGEVTPNSLSTSYKTVSLPLSSPNIKLNLTSPKRGQKIEEGWKEVVRRSKKLSVPASVVSRIMGRGGCNITAIQDVTGAHIDVDKQKDKNGERMITIRGGTESTRYAVQLINALIQDPAKELEDLIPKNHIRTPASTKSIHANFSSGVGTTAASSKNAFPLGAPTLVTSQATTLSTFQPANKLNKNVPTNVRSSFPVSLPLAYPHPHFALLAAQTMQQIRHPRLPMAQFGGTFSPSPNTWGPFPVRPVNPGNTNSSPKHNNTSRLPNQNGTVLPSESAGLATASCPITVSSVVAASQQLCVTNTRTPSSVRKQLFACVPKTSPPATVISSVTSTCSSLPSVSSAPITSGQAPTTFLPASTSQAQLSSQKMESFSAVPPTKEKVSTQDQPMANLCTPSSTANSCSSSASNTPGAPETHPSSSPTPTSSNTQEEAQPSSVSDLSPMSMPFASNSEPAPLTLTSPRMVAADNQDTSNLPQLAVPAPRVSHRMQPRGSFYSMVPNATIHQDPQSIFVTNPVTLTPPQGPPAAVQLSSAVNIMNGSQMHINPANKSLPPTFGPATLFNHFSSLFDSSQVPANQGWGDGPLSSRVATDASFTVQSAFLGNSVLGHLENMHPDNSKAPGFRPPSQRVSTSPVATSAPPTLGQPKGVSASQDRKIPPPIGTERLARIRQGGSVAQAPAGTSFVAPVGHSGIWSFGVNAVSEGLSGWSQSVMGNHPMHQQLSDPSTFSQHQPMERDDSGMVAPSNIFHQPMASGFVDFSKGLPISMYGGTIIPSHPQLADVPGGPLFNGLHNPDPAWNPMIKVIQNSTECTDAQQIWPGTWAPHIGNMHLKYVN
Protein: AH domain-containing protein (D1MN62)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MMHIDTAQVAAKVESFKKWTIGTFKNSKQQLLEHMGKIDKTVDPEFEAQCEVLKDIHRRYGLVVAAAKNFSHVLTQMAEAEKKLSESFYQLSMKEEQIKAQCTMTSETMRGVGEQAASLDACLRYFISSMETVYNQTITDTLHTIYNTESARIEYDVDRNDISAATNPPQGQLTKNLPVGATEKCEEKKAKYEKLKNDAKIKMRLLEENRISVVAAQLEKLQSALAAYYSGNAKLLEASVRELSFLQSPQPSFIPTM
Protein: Germinal center-associated signaling and motility-like protein (Q5JQS6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGNYLLRKLSCLGENQKKPKKGNPDEERKRQEMTTFERKLQDQDKKSQEVSSTSNQENENGSGSEEVCYTVINHIPHQRSSLSSNDDGYENIDSLTRKVRQFRERSETEYALLRTSVSRPCSCTHEHDYEVVFPH
Protein: Kelch-like protein 38 (Q2WGJ6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDEESLDGLLFKDHDFSSDLLRQLNSLRQSRILTDVSICAGAREIPCHRNVLASSSPYFRAMFCSSFREKSEAKVQLKGIDPPTLDQIVSYVYTGEAHIATDNVLPVMEAASMLQFPKLFEACSSYLQSQLAPSNCLGMIRLSEILSCETLKKKAREVALTSFPEVAASADLKELCALELRDYLGDDGLCGEEEKVFEALMVWIKHDLQARKRYMQELFKQVRLQYIHPAFFHHFIANDALLQSSPACQIILETAKRQMFSLCGTTVPDCKLLLHVPPRNSYQDFLILLGGRKDSQQTTRDVLLYSKQTGQWQSLAKLPTRLYKASAITLHRSIYVLGGMAVSSGRSLVSHNVYIFSLKLNQWRLGEPMLVARYSHRSTAHKNFIFSIGGIGEGQELMGSMERYDSICNVWESMASMPVGVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNSWFKMETRMIKNVCAPAVVLGERIVIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHKLFDHACLTLQCIPRTSGLP
Protein: exo-alpha-sialidase (EC 3.2.1.18) (Q8XMY5)
Organism: Clostridium perfringens (strain 13 / Type A)
Interaction partners:
- Arylsulfatase
- Hyaluronoglucosaminidase
- exo-alpha-sialidase
- Alpha-galactosidase
- Alpha-galactosidase
- Hyaluronidase
- Hyaluronidase
- Beta-galactosidase
Sequence:
MKSKKIIATLVASLVISNMGGYLVKANPNVNHKAVIIEDRQAIIETAIPQSEMTASATSEEGQDPASSAIDGNINTMWHTKWNGSDALPQSLSVNLGKARKVSSIAITPRTSGNNGFITKYEIHAINNGVETLVAEGTWEENNLVKTVTFDSPIDAEEIKITAIQGVGGFASIAELNVYEIKGEVDEIANYGNLKITKEEERLNITGDLEKFSSLDEGTIVTRFNMNDTSIQSLIGLSDGNKANNYFSLYVSGGKVGYELRRQEGNGDFNVHHSADVTFNKGINTLALKIEKGVGAKIFLNGSLVKTVSDPNIKFLNAINLNSGFIGKTDRANGYNEYLFRGNIDFMNIYDKPVSDNYLLRKTGETKAPSEDSLLPDDVYKTQPVELFYPGYLESRGYRIPALETTKKGTVLASIDVRNNGDHDAPNNNIDVGIRRKEVNGEWEEGKVILDYPGKSAAIDTSLMSATIEENGIEKERIFLIVTHFPEGYGFPNTEGGSGYKEIDGKYYFILKDAQNNEYTVREDGIVYNSEGNQTDYVMKNDKTLIQNGEEVGNALLSNSPLKAVGTAHIEMIYSDDDGKTWSEPEDLNPGLKKEWMKFFGTAPGKGIQIKNGEHKGRLVFPIYYTNQNNFQSSAVIYSDDFGETWKLGESPIDTASVSSETVSSGTQLTECQVVEMPNGQLKLFMRNTGSYTKIATSFDGGATWHDEVPEDTSLREPYCQLSVINYSGKINGKDAIIFSNPDASSRVNGSVKVGLINENGTYDNGEPRYEFDWIYNKTVKPGSFAYSCLTELPDGNLGLFYEGEGAGRMAYTEFDLNYLKFNASEDSPSASVQSIEVLDEDLAYNSGEEVSIKVNFNQLVSIIGDRKITLDIGGVDVPLNMVNYEGKSSAIFKGTIPEGINQGNYEIKLKENNTLELNTVYNKVSTFNGLDNTGINVQIGELKTTVGNSTIKVNDEVQVGSAFEAILGIEGLNGDTEVYSAEYLFEYNVEAFILNEITSFNDSLFVKSKEVEPGKVRILVASLGNEIEKDSDLVKVNLTPKISSELEVLGLTTALVGAGDGNTHDLELSSKEVKINEEASGEIVVNPVQNFEIPEINKKNVKLTWNAPITTEGLEGYVIYKDGKKLSEVPAESTEFVVSKLNRHTIYNFKVAAKYSNGELSAKESKTIRTAR
Protein: Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219) (Q86XT9)
Organism: Homo sapiens (Human)
Function: Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20353938}; Single-pass membrane protein {ECO:0000269|PubMed:20353938}.
Interaction partners:
- Insulin-like growth factor-binding protein 3
- Interleukin-13 receptor subunit alpha-2
- Chitinase-3-like protein 1
Sequence:
MGNCQAGHNLHLCLAHHPPLVCATLILLLLGLSGLGLGSFLLTHRTGLRSPDIPQDWVSFLRSFGQLTLCPRNGTVTGKWRGSHVVGLLTTLNFGDGPDRNKTRTFQATVLGSQMGLKGSSAGQLVLITARVTTERTAGTCLYFSAVPGILPSSQPPISCSEEGAGNATLSPRMGEECVSVWSHEGLVLTKLLTSEELALCGSRLLVLGSFLLLFCGLLCCVTAMCFHPRRESHWSRTRL
Protein: Phosphodiesterase (EC 3.1.4.-) (Q57V52)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGCGIATLFPYSKGSSVSPTTVRGENYILSTSSDLKELKAVVRVPLEQSDPPRMLGKEKYIISQGAVVMDDRPVAHMPSAGILLLYCTTDHIDFTVSYLEHDTRAIFAHSFTDKELADSKDDAGITFSWGSFFKSLASDVQRQKATVTPAPGGGKNVNFTVTNIKESDLMYKYICKLPLVSLPGDEDYRVRVVEYIVEPMTRMTQIRRRRSEMICPRLSLESLECERVVRSAMLQESKKKVERLLADLKPLREESSVAAQKTMELAFCVNDLRKRLRLLCAAPPSKDPLDVLYDKGGAQYFEHTTQAVKYYPVETDVDTVVLACIRAAFPLPPGAPAESAMDVLDLPELQPLLDNSSRQAVRDVLEILCGIDKWGYDVIRLEIMTNGNSLFYTTYTILYKLDLVARFQLDDATLQRFLLGVQSGYHPNPYHNSMHAADVTQVNYYIIFIAGMKERCQLRPEEQLGAVLAAAVHDFDHPGLNNNFHTRTNAYLSTLYNDRSILENHHIASVFQLLKHPSYNVLAPLNDEQFRTVRETMVEMVLATDMSNHGTILKRFQSRLVEASDWSANKQDVLVALSMSIKTADLSNCIRPYYIYSEWSSYIAQEFYKQGDEEERSNLSISPFMNRKTSDKDFPEGQKSFITYVVAPMMEAVVMFLPHLRFTLQLCENNRTAWCE
Protein: Aquaporin 3, putative (Q585Q8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Expression site-associated gene
Sequence:
MSDEKINVHQYPSETDVRGLKARNGGACEVPFEENNEPIPNRSANPQEKNENELVGDNADNEAHDAVDVNYWAPRQLRLDYRNYMGEFLGTFVLLFMGNGVVATTILDKDLGFLSITLGWGIAVTMGLYISLGISCGHLNPAVTLANAVFGCFPWRRVPGYIAAQMLGAFVGAACAYGVYADLLKQHSGGLVGFGDKGFAGMFSTYPREGNRLFYCIFSEFICTAILLFCVGGIFDPNNSPAKGHEPLAVGALVFAIGNNIGYASGYAINPARDFGPRVFSAILFGSEVFTTGNYYFWVPLFIPFLGGIFGLFLYKYFVPY
Protein: LTBP1 protein (B7ZLY3)
Organism: Homo sapiens (Human)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPDISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
Protein: ADAM metallopeptidase with thrombospondin type 1 motif 9 (H0Y859)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
XECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCSEFPCPQWKSGDWSECLVTCGKGHKHRQVWCQFGEDRLNDRMCDPETKPTSMQTCQQPECASWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLPRPVAKEECSVTPCGQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTANDCVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSHLESDYCKHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSLQPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQPSHLCHTDLKPEERKTCRNVYNCELPQNCKEVKRLKGASEDGEYFLMIRGKLLKIFCAGMHSDHPKEYVTLVHGDSENFSEVYGHRLHNPTECPYNGSRRDDCQCRKDYTAAGFSSFQKIRIDLTSMQIITTDLQFARTSEGHPVPFATAGDCYSAAKCPQGRFSINLYGTGLSLTESARWISQGNYAVSDIKKSPDGTRVVGKCGGYCGKCTPSSGTGLEVRVL
Protein: Lethal giant larvae homologue 2 domain-containing protein (TOM-1 isoform D) (Q14DX2)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MDRAKKKFASAIDGLRSLHNRTEINVDEKIQSEHCRFTRVVRHGLPEDPRCFAYDPVQRLIAIGTGRGHIRIIGDAGVDYLLKHESGEPVLHMQFLVNEGGLITSCGTDSIHLWNYRQKTAEIVHTVQLSKESVSCIHLPVAGKWLFIGTDKGNVYFLCLNSFLLSPYVINWNKAIDLSCRVHPGPVRQLAVSPAENTKLLIVYDKGIVVQWNLGTREVDRYPLDPPIKSVNWHFDGRQILTGNVDGSISLYNHKKSTEAIQRTTPHGSGPCRPIQQVEWKHMSETESIIMFSGGMPTDDGLPMPALTILKGGKSATVLEMDWPIIQFIPLNQNIWNSIPQCPHSVAVLLKHDFMVLDLNQNGHPVIESPHAMNIHESPVTCMAYYSDCPLDLIGALTLVGTKQRNKEFSARSWPVTGGLGRECATGHQELVVTGHKDGSLKFWQETGEHLQILYKLKSSSHFERLEEMETSDKVSHAVKYIELCLESRQLLVAGISGQVTLFRFTKQEICGTIAVVNIPLLGNLSSNLPNNDFDKSPVPNGPGKEIRRQRKIVSRESTNSLDTSDSGDERIVPFKVRGAPVKRPPGFVPELACFVPWHSHAKVDQITTICLNSSYGIIAIGTSSGLALVDTTQCALIYSWTTNELYGSDPTPAIQLSMQLSDAASPLESPISLEAPKRIISEQKQRSFDARRPQLFKTQSVVENGSLSRGDSQRESPSSGRQLNTSSPSTSSQSLERSMSTQPQESITSLSFIHSYSKKNDSKMSPCLWVGTSAGASLALNLILPEDRFTSTIVVAPSAVEECTVVRLKGQVISQSFMDNTFCIISPASESYKEAAKEQSATSPDRSLLNRVNTKASLAPQYSSSIDSNDEISQILIVAAENEVKVVALPTFSQLYVQKFDEIPLVKATPTHIRGYPCLMCLSAAGQIIMLSLPSLRILQTSTIFPHSVEIDDPLCQKTAFSDHGLGVYMASQTEMEKYTMCSEIAEQTGESLGELFVPCEMPEQPKNNSFLKGVSSIFGGTPRNDPNDIDAILSENMGVKNSSGVNPMRSVARTIPGPSVQMDRAQAGGVSAGQAAAMALQNLNERTEKLNATVDATENLKNNAMSLSSRTGKLVEKYEKKKWYNF
Protein: Magnesium dechelatase SGR1, chloroplastic (EC 4.99.1.10) (Protein NONYELLOWING 1) (AtNYE1) (Protein STAY-GREEN 1) (Protein STAYGREEN 1) (O82741)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Magnesium chelatase involved in chlorophyll a degradation in the chlorophyll-protein complexes of photosystem I (PSI) and photosystem II (PSII). Contributes to the degradation of PSI and PSII in the thylakoid membranes. Required to trigger chlorophyll degradation during natural and dark-induced leaf senescence (Probable). Mediates chlorophyll degradation during embryo degreening. Recombinant SGR1 possesses high dechelating activity against chlorophyll a, very low activity against chlorophyllide a, and no activity against chlorophyll b. Magnesium dechelation of chlorophyll a by SGR1 activates chlorophyll b degradation by inducing the expression of NYC1, an enzyme involved in chlorophyll b degradation.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:17468209, ECO:0000269|PubMed:22366162}.
Interaction partners:
- 7-hydroxymethyl chlorophyll a reductase, chloroplastic
- Probable chlorophyll
- Chlorophyllase-1
- Chlorophyllase-2
- Pheophorbide a oxygenase, chloroplastic
- Chlorophyllide a oxygenase, chloroplastic
- Pheophytinase, chloroplastic
- Chlorophyll synthase, chloroplastic
- Chlorophyll
- Protochlorophyllide reductase B, chloroplastic
Sequence:
MCSLSAIMLLPTKLKPAYSDKRSNSSSSSSLFFNNRRSKKKNQSIVPVARLFGPAIFESSKLKVLFLGVDEKKHPSTLPRTYTLTHSDITAKLTLAISQSINNSQLQGWANRLYRDEVVAEWKKVKGKMSLHVHCHISGGHFLLDLFAKFRYFIFCKELPVVLKAFVHGDGNLLNNYPELQEALVWVYFHSNVNEFNKVECWGPLWEAVSPDGHKTETLPEARCADECSCCFPTVSSIPWSHSLSNEGVNGYSGTQTEGIATPNPEKL
Protein: InaF-A (A8JUT0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GEO11103p1
- InaF-D
- Uncharacterized protein, isoform B
Sequence:
MASSTLDLGEKPEENDDVRLPKEQQPPAFFESKTFRIISIFLYLGGISGLGMVLALYYLMFFDSSMPDIHLKFPVSIGGHPVQKVHEYQ
Protein: Galanin receptor 2a (F1R332)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Receptor for the hormone galanin. Receptor for the hormones spexin-1 and spexin-2.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Galanin peptides
- Galanin peptides-like precursor
- Spexin prohormone 1
- Pro-opiomelanocortin protein
Sequence:
MNASQQIHVFSSHWKVESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQMDLDGTTVCIPAWSVHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWFGHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGCAFRNRVVNRIHTVQPAQTVSLMEAASSEGSNHCDGSTRGRLWSKSSKKMMTSAFMTFNVT
Protein: Torso-like protein (P40689)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable ligand that binds to the torso receptor. Implicated in a receptor tyrosine kinase signaling pathway that specifies terminal cell fate.
Subcellular location: Secreted {ECO:0000269|PubMed:12814553, ECO:0000269|PubMed:8107870}. Note=Is a component of the vitelline membrane (VM, the inner layer of the eggshell).
Interaction partners:
- Protein trunk
- Tyrosine-protein kinase receptor torso
- Homeotic protein bicoid
- Female sterile
- EG:8D8.1 protein
Sequence:
MRSWPGLFWLLTLALLADGGRRESQLRIGKAINIFLRYGYLGISMRVIPLNDNSEPDRWVFKEPTKNIYRNLSGLAESHEDTTPGIFHGDFHMEFCENRRQLFQAYFRDFSIERMDKPWEAFTGGWFPDNAAKKLGINTSFIQGDYSYVLVRVVRFRETGRLNAEIPVHQPLEPDVRSRMDQLQIGNITSAVRFMEDVGTHYVNSYTTGNSLYQVFVYSRKNYSMIKERIKSKGLNGLSKLDLYNYFAPWFAAHLGQIRSASANATVERWARRKLQYEYYVVKYVTLLKLHGNSTLLRSLDSLLGNDAILQLDLKSLKPIFREEPEKESWYHEVLDNNVKLWELNMPQSHPTR
Protein: Large ribosomal subunit protein eL22A (60S ribosomal protein L22-A) (L1c) (RP4) (YL31) (P05749)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Large ribosomal subunit protein eL39
- Small ribosomal subunit protein RACK1
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein eL38
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL11A
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein eL32
- Small ribosomal subunit protein eS21B
Sequence:
MAPNTSRKQKIAKTFTVDVSSPTENGVFDPASYAKYLIDHIKVEGAVGNLGNAVTVTEDGTVVTVVSTAKFSGKYLKYLTKKYLKKNQLRDWIRFVSTKTNEYRLAFYQVTPEEDEEEDEE
Protein: Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC 3.1.11.3) (P00638)
Organism: Escherichia phage T7 (Bacteriophage T7)
Function: Plays an essential role in phage DNA replication by participating in the removal of DNA-linked RNA primers. Participates also in T7 DNA packaging, host DNA degradation and phage genetic recombination.
Interaction partners:
Sequence:
MALLDLKQFYELREGCDDKGILVMDGDWLVFQAMSAAEFDASWEEEIWHRCCDHAKARQILEDSIKSYETRKKAWAGAPIVLAFTDSVNWRKELVDPNYKANRKAVKKPVGYFEFLDALFEREEFYCIREPMLEGDDVMGVIASNPSAFGARKAVIISCDKDFKTIPNCDFLWCTTGNILTQTEESADWWHLFQTIKGDITDGYSGIAGWGDTAEDFLNNPFITEPKTSVLKSGKNKGQEVTKWVKRDPEPHETLWDCIKSIGAKAGMTEEDIIKQGQMARILRFNEYNFIDKEIYLWRP
Protein: Zinc-responsive transcriptional regulator ZAP1 (P47043)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcription regulator controlling zinc-responsive gene expression. Binds to zinc-responsive elements (ZREs) (consensus sequence 5'-ACCYYNAAGGT-3') in the promoter of target genes. Recruits SWI/SNF, SAGA, and Mediator complexes as coactivators in a zinc-responsive manner. Involved in zinc ion homeostasis by zinc-responsive transcriptional regulation of the zinc uptake system genes ZTR1 and ZTR2. Positively regulates ETR1 expression, affecting mitochondrial function.
Subcellular location: Nucleus {ECO:0000269|PubMed:10899124, ECO:0000269|PubMed:21799889}.
Interaction partners:
- Zinc-regulated transporter 1
- Zinc-regulated transporter 2
- ADIPOR-like receptor IZH2
- ADIPOR-like receptor IZH1
- ADIPOR-like receptor IZH4
- ADIPOR-like receptor IZH3
- Zinc-regulated transporter 3
- Vacuolar zinc transporter ZRC1
- Orotate phosphoribosyltransferase 2
- Orotate phosphoribosyltransferase 1
Sequence:
MDALTPRDSPKRDDSMATSAATAASAKPDALTIGKEGIVHGHIHNYNNLTYIHGHLHHSAPVNDSSASATPAAAAVADAATSAFASGASHDMGGDCHVNEKCKEYTDCQHFEFLNYHNNPSLTKYNDTATYNSNNHSFANNFHSVASDPTSPQQNSKSDLPRRKDSWFNDDLILLPSSKKNKPNPPPGSDDCYCTPKILEICCDETHPKSEANIKQGESDQPTKKDISENGNDVAIFTDVKNDHLMPNFNLHDQYCNSTNHDSHNHNNTVPDSFSQLMSHLSEIDCDLTCDTPCTASTSATSGHKFVQDHQSSNNDDVFHKYCKFCEESTDNQPCSKHMHLESKPPQLPPKCSSLRKPTNTLQGTNHAYHEHILNTDMDLKILEDLCNISSLYEVPFGKHINHHDHNNAGNGCDGSSTGNNENGNQTMNLLLSSINRCNPKNNLNGSNNNTAGATSTDHQHHHHRIQFHSHKPNRNNIVNNSGISAANTTADLTNNDLNDLISREYSYERFRNQSEPPSLPKVTHQNQKNRRSWPTKDLESTDFSSLEDSLPSSISPPIQTTSTINFNWCFKEEKNNDLKCKWKECPESCSSLFDLQRHLLKDHVSQDFKHPMEPLACNWEDCDFLGDDTCSIVNHINCQHGINFDIQFANPDSFLPGSISKEKHHLLHCPNPQTHEVSKADGAPDMTSANDVSNIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVHLTRGKSEYQCLWHDCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKKYKCSDCSKSFDDLGKLNSQKVKCALERKPYL