Protein: Plectin (PCN) (PLTN) (300 kDa intermediate filament-associated protein) (IFAP300) (Plectin-1) (Q9JI55)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q15149}. Cell junction, hemidesmosome {ECO:0000250|UniProtKB:Q15149}. Cell projection, podosome {ECO:0000250|UniProtKB:Q9QXS1}. Note=Localized to the cortex of myotube podosomes. {ECO:0000250|UniProtKB:Q9QXS1}.
Interaction partners:
Sequence:
DGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQNGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKSRSKGIYQSLEGAVQAGQLQIPPGFHPLDVEKEWGKLHVAILEREKQLRGEFERLECLQRIVSKLQMEAGLCEEQLNQADSLLQSDIRLLASGKVAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPVTQVTVQSTQRRPELEDSTLRYLQDLLAWVEENQRRIDSAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRECLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKETQNTGDRLLREDHHARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETMRREYSCDRSITVTRLEDLLQDAQDEREQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLMAVCDYKQVEVTVHKGDQCQLVGPAQPSHWKVLRGPSSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQNLSRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQGEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKAHEEQLKEAQAVPATLQELEATKASLKKLRAQAEAQQPVFDTLRDELRGAQEVGERLQQRHGERDVEVERWRERVNQLLERWQAVLAQIDVRQRELEQLGRQLRYYRESADPLSSWLQDAKRRQEQIQAVPIPNSQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEGEAALEKQRQLAEAHAQAKAQAELEAQELQRRMQEEVARREEAAVNAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAQAEAAQEKQRALQALEELRLQAEEAERRLRQAQAERARQVQVALETAQRSAEVELQSKRASFAEKTAQLERTLQEEHVTVTQLREKAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQRSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREATAATHKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEADRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAALHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEILALKVSFEKAAAGKAELELELGRIRSSAEDTMRSKEQAEQEAARQRQLAAEEEQRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQSMLERLRGEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLVEETQGFQRTLEVERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQRQMEQEKQELVASMEEARRRQCEAEEAVRRKQEELQHLELQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIAATQAAAAKALPNGRDALDGPSMEVEPEHAFEGLRQKVPALQLREAGILSAEELQRLEQGHTTVAELSQREDVRQYLQGRSSIAGLLLKPTDEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEPVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLLVRDHAIRLLEAQIATGGIIDTVHSHRVPVDVAYQRGYFDEEMSRILADPGDDTKGFFDPNTHENLTYLQLLERCVEDPETGLHLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIVITVVEEQERKGQLCFEGLRALVPAAELLESGVISHELYQQLQRGERSVREVAEADSVRRALRGASVIAGVWLEEAGQKLSIYEALKKDLLQPDVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPELHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGMVDPSKSHRVPLDVAYARGYLDKETNRALTSPRNDARVYLDPSSQEPATYSQLQQRCRADQLTGLSLLPVSEKAVRARQEEVYSELQARETLEKARVEVPVGGFKGRTMTVWELISSEYFTQEQRQELLRQFRTGKVTVEKVIRIVITIVEEVETQRQERLSFSGLRAPVPASELLAAKILSRAQFDQLKEGKTSVKDLSEVGSVRTLLQGSGCLAGVYLEDSKEKVTIYEAMRRGLLRPSTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGTTISLFQAMKKGLVLREHAIRLLEAQIATGGIIDPVHSHRLPVDVAYQRGYFDEEMSRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLKGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSDMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKSLREVLEMESAWRYLYGTGSVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLKRCRRDDGSGQMLLPLSDARRLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKTLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDRLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLRLLPLKEKKRERKTSSKSSVRKRRVVIVDPETSKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAITENLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTTGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPPASLGGPESAVA