wanglab/gogpt-training-data huggingface dataset:
Protein: alanine transaminase (EC 2.6.1.2) (A0A8I6ARL0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQRAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPERSPRDRILTLESMNPQVKAVEYAVRGPIVLKAGEIEMELQRGIKKPFTEVIRANIGDAHAMGQQPITFLRQVMALCTYPNLLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFITRRDGVPADPDNIYLTTGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEDNCWALNVDELRRALRQAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYQMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVPGEESFEQFTREKESVLGNLAKKAKLTEDLFNQVPGIQCNPLQGAMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLHKVKDFHLKFLEKYS
Protein: Uncharacterized protein YIL060W (P40519)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MMIIIFIELCRIADSLLWIPKSSRRTSSTFYIPNIIALLKMESQQLSQNSPTLHIHTCGSKIGTLFLRFTKVAIGTSLIVGAGVAMEVSVPLPPQPLYSRSEVPSVELCGIVAICRSPPSVYPTCRPISLSKKIVSGLVRTNSS
Protein: Soluble lytic murein transglycosylase (EC 4.2.2.n1) (Exomuramidase) (Peptidoglycan lytic exotransglycosylase) (Slt70) (P0AGC3)
Organism: Escherichia coli (strain K12)
Function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division.
Subcellular location: Periplasm. Note=Tightly associated with the murein sacculus.
Interaction partners:
- Membrane-bound lytic murein transglycosylase D
- Membrane-bound lytic murein transglycosylase A
- Membrane-bound lytic murein transglycosylase B
- Endo-type membrane-bound lytic murein transglycosylase A
- Anhydromuropeptide permease
- Membrane-bound lytic murein transglycosylase F
- Membrane-bound lytic murein transglycosylase C
- D-alanyl-D-alanine endopeptidase
- Endolytic peptidoglycan transglycosylase RlpA
- Endolytic murein transglycosylase
Sequence:
MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAWDNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQSRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGKSQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAIISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNEDQIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTWLARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYELKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYAFNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAWNPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQQFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAYYRYFMGDKPTLMSATEWGRRY
Protein: Ankyrin-repeat and fibronectin type III domain containing 1 (F6X7B3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
RIGRRFACFAQRLSYRRKQSQCDLLNESTGHLPATCSSAASKSLSWNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELGIVACFT
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (G8XQW2)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
- UPF0235 protein At5g63440 isoform X1
- UPF0235 protein At5g63440-like isoform X1
- Nuclear pore complex protein NUP88
- Zinc finger CCCH domain-containing protein 40-like
- SNW/SKI-interacting protein
- SNW/SKI-interacting protein-like
- Nuclear pore complex protein NUP155-like
- Pre-mRNA-splicing factor SYF1
- Nuclear pore complex protein NUP155-like
- Pre-mRNA-splicing factor SYF1
Sequence:
MASNPKVFFDMTIGGQPAGRIVMELFADCTPRTAENFRALCTGEKGVGRSGKPLHYKGSSFHRVIPNFMCQGGDFTAGNGTGGESIYGSKFADENFIKKHTGPGILSMANAGPGTNGSQFFICTAKTEWLDGKHVVFGQVVEGMDVVKAIEKVGSSSGRTSKPVVVADCGQLS
Protein: MICOS complex subunit (A0A0J9YWW6)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU363021}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
XFFPRLGVIGFAGLIGLLLARGSKIKKLVYPPGFMGLAASLYYPQQAIVFAQVSGERLYDWGLRGYIVIEDLWKENFQKPGNVKNSPGTK
Protein: NAD-dependent protein deacetylase HST2 (EC 2.3.1.286) (Homologous to SIR2 protein 2) (Regulatory protein SIR2 homolog 2) (P53686)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: NAD-dependent histone deacetylase that is involved in nuclear silencing events. Derepresses subtelomeric silencing and increases repression in nucleolar (rDNA) silencing. Its function is negatively regulated by active nuclear export.
Subcellular location: Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm, but is largely cytoplasmic owing to efficient nuclear export. Nuclear exclusion is mediated by the exportin CRM1.
Interaction partners:
- Nicotinamidase
- Glutamine-dependent NAD
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
- NAD-capped RNA hydrolase NPY1
- NAD
- Uridine nucleosidase
- Purine nucleoside phosphorylase
- Nicotinamide mononucleotide adenylyltransferase
- Histone H3
Sequence:
MSVSTASTEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDNSKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE
Protein: Lysophospholipase 2 (EC 3.1.1.5) (Phospholipase B 2) (Q03674)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Sequentially removes both fatty acyl groups from diacylglycerophospholipids and therefore has both phospholipase A and lysophospholipase activities. However, it does not display transacylase activity. Substrate preference is phosphatidylserine > phosphatidylinositol > phosphatidylcholine > phosphatidylethanolamine. The substrate specificity is pH- and ion-dependent. In contrast with activities observed at optimum pH 3.5, the order of substrate preference at pH 5.5 is phosphatidylserine = phosphatidylethanolamine > phosphatidylcholine > phosphatidylinositol.
Subcellular location: Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Interaction partners:
- Lysophospholipase NTE1
- Lysophospholipid acyltransferase
- Glycerophosphocholine phosphodiesterase GDE1
- Lysophospholipase 1
- Triacylglycerol lipase 4
- Triacylglycerol lipase 5
- Lysophospholipase 3
Sequence:
MQLRNILQASSLISGLSLAADSSSTTGDGYAPSIIPCPSDDTSLVRNASGLSTAETDWLKKRDAYTKEALHSFLSRATSNFSDTSLLSTLFSSNSSNVPKIGIACSGGGYRAMLGGAGMIAAMDNRTDGANEHGLGGLLQSSTYLSGLSGGNWLTGTLAWNNWTSVQEIVDHMSESDSIWNITKSIVNPGGSNLTYTIERWESIVQEVQAKSDAGFNISLSDLWARALSYNFFPSLPDAGSALTWSSLRDVDVFKNGEMPLPITVADGRYPGTTVINLNATLFEFTPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVNKDQCVSGYDNAGFVIATSASLFNEFSLEASTSTYYKMINSFANKYVNNLSQDDDDIAIYAANPFKDTEFVDRNYTSSIVDADDLFLVDGGEDGQNLPLVPLIKKERDLDVVFALDISDNTDESWPSGVCMTNTYERQYSKQGKGMAFPYVPDVNTFLNLGLTNKPTFFGCDAKNLTDLEYIPPLVVYIPNTKHSFNGNQSTLKMNYNVTERLGMIRNGFEAATMGNFTDDSNFLGCIGCAIIRRKQESLNATLPPECTKCFADYCWNGTLSTSANPELSGNSTYQSGAIASAISEATDGIPITALLGSSTSGNTTSNSTTSTSSNVTSNSNSSSNTTLNSNSSSSSISSSTARSSSSTANKANAAAISYANTNTLMSLLGAITALFGLI
Protein: Nuclear hormone receptor family member nhr-136 (O01930)
Organism: Caenorhabditis elegans
Function: Orphan nuclear receptor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- Glycosyltransferase family 92 protein R07B7.12
Sequence:
MLPDFITVPSTSEKCLSPELLLPNMDENLEDSKPSSLKYQKAMMSRGTCPSNCKVCRHSATGYHYDVPSCNGCKTFFRRSILDGRKYTCLKMRKCLSGTEPVDLSRRMCRACRFEKCVEAGMNPSAIQADMKTTDGELLRKEIMIKQKTAVDFLNTPQVIMSFEDKVQGIIGKLTVMELKIEPLYTGGLPPGNRDIRKLDELIDAPLILSYDEIPNLKYCPSVDELTGEIKPSGACYIHCGYLASIEYSKMFDFAHKIDVASKATLIKHATIMCADIMTAFFSYYQRKSDRLIHPNGMFAGPPKYRYGEAGTKYQASMQRTLATVLRHELNRIEYMLLKAIVLCNPAVSSLSISVQQIIGKEREEYVRTLLTYCLLNYGSVHGPSRFSALLAIMSVLESQQKNAKDFHLLAKATILKDAVRYTRISNLYEQIMES
Protein: Uncharacterized protein (Q581Z4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- C2H2-type domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Large ribosomal subunit protein uL4m
- AMP-dependent synthetase/ligase domain-containing protein
Sequence:
MLQINAFKLVRATPFLLKRTGKPADTPDYKQVYLPYDAAPTERELERERRRFKQAHHGRMEHRKLVEVKEVPLNVYTYGKEGMSLPIAIFKDQKDPVIGPEWTYPGIYENKIAAQHWYTEELFDKESKEAFESPWQQQILDNQVKRRMAKVMFRMRQVNMKAVDLFQKERGSSRRSGGAGEKGKDGGGKK
Protein: Urokinase-type plasminogen activator (U-plasminogen activator) (uPA) (EC 3.4.21.73) [Cleaved into: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B] (Q05589)
Organism: Bos taurus (Bovine)
Function: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P00749}.
Interaction partners:
- Plasminogen activator inhibitor 1
- Urokinase plasminogen activator surface receptor
- Plasminogen
- Vitronectin
- Matrix metalloproteinase-9
- Glia-derived nexin
- Cathepsin B
- Uncharacterized protein
- 72 kDa type IV collagenase
- Serpin domain-containing protein
Sequence:
MRVLLACLLVCALVVSDSDGSNEVHKESGESNCGCLNGGKCVTYKYFSNIQRCSCPKKFQGEHCEIDTSKTCYQGNGHSYRGKANRDLSGRPCLAWDSPTVLLKMYHAHRSDAIQLGLGKHNYCRNPDNQRRPWCYVQIGLKQFVQFCMVQDCSVGKSPSSPREKEEFQCGQKALRPRFKIVGGQVTNAENQPWFAAIYRRHRGGSITYLCGGSLISPCWVVSATHCFIDHPKKENYIVYLGQSRLNSDTRGEMQFEVEKLILHEDYSAESLAHHNDIALLKIRTSRGQCAQPSRSIQTICLPPEHEDAHSRTRCEITGFGKENPSDYRYSDELKMTFVSLVSHEVCQQPHYYGAEVTDKMLCAADPQWETDSCQGDSGGPLVCTIQGRLTLTGIVSWGRDCAMKYKPGVYTRVSKFLPWINTHTRGEINLVL
Protein: TRPA2 (Transient receptor potential cation channel subfamily A member 1b) (Q5UM14)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MQFGKELVRRNSFYKCVINEDETEESADVFELAFKGKASAIDRLIQKGPEHLSLRDENGASLLHYASAGGNLDIIRLIVSIVGPEVLNVQDEQGRTPLHWAVEQDQQQSCAVLLDLGADPNILNNALMGPLHLAVTKQYNHLAEVLLSCDKTNSNLEGDLGNTPVMLACSNNNCQALQILIKRGAKMCIQNKLGHYPIHTVAFAGAKEAMEMVLKIGEELGVSSTLHINYLDKSKSTPLHLAVRGGNIEVIKLCILKGAKVEQHQSGKCTALHFACSQGSLEAVKIMLSSYNRTEDIVNIRDGANRTPLHRATLFDHVELAEYLISKPNTLSLDLICLGKGAEIDSIDCKGLSPLLLASSCSAWKTVAYLLSIGADFKIKEKTGRNFLHFVILQPKGLKNLPETVLQSTAVKEMLSDEDVEGCTPLHYACKLGIHDSVKNMLGLNICLGQKSREKKSALHFAAEYGRINTCHRLLETLTDSKMLNDWDEKGLTPLHLASRAGHAQVVDLLLRKGALFQSDYKGWTCLHHAAAEGYTQTMKILLAANVKLLDEKNEDGNTALHIAAQAGHVSAVLLLLDRGAEIALNDADNSFLHEAVRNERREVVNATIEHERCDESMTSFKAKSRCVVLDIIEFLPESFQHLLDQCITESDHDANSQDYHIMYNFQWLQAPIQLKKYAKTDKTKAFQPLAALNAMVRYNRLELLIHPLSRKYLEMKWTAYGSKVHFLNLAIYLLGLLPLTYLILNLRPSQDFSKGNGTSVIMVPVSFSEQQYLISVCIIMVIVMNVYSICKEVVQLAQQRVNYFTDFSNPADWSAAISALVFVVPMCCSVEATWQWEAGAYAILTSWIGFLLYFQRFERIGIYVVMFNGIVRTLVCIMVLFVFLLLAFGLAFYALMLHRPEFSSISLALAQTFVMTVGELNYQSTFLNSYEEGHMAFPAITYFVFVFFVLLMPILLMNLMIGLAVGDIAEVQRNAELKRIAMQIDLHTALEEKLPYWFLKRVDKPSTVVYPNKCKKVLLEALVHGEIQNTVRTRLNLCSRKEGLLERELHKQKNRLKEMSCMLEKQHNLLKLIIQKMEITSEADEYDGPQNHGALKQHTSSTSQKSKWVPLLQAIKAKK
Protein: Transcription factor GATA-5 (GATA-binding factor 5) (P43692)
Organism: Gallus gallus (Chicken)
Function: Probably involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Nkx-2.5
- Proteasome activator complex subunit 3
- Uncharacterized protein.
- Zinc finger protein ZFPM2
- T-box transcription factor TBX20
- T-box transcription factor TBX5
- Heart- and neural crest derivatives-expressed protein 2
- Transcription factor 21
- Zinc finger protein, FOG family member 1.
Sequence:
MYQGLALAPNHGQSAYSHDSGNFLHSSAGSPVYVPTTRVPSVLQTLPYLQSCEPHQSHLGNPPGWAQSSGETTAFNAGSPHPPSGFSYPHSPRAAAPRGVDGAYQGPLLLGGGGREQYGNALVRSVNGSYSSPYPAYVTPELPPSWTAGHFESSVLHSLQTRQAALPGRRSTFEYLEEFPGDGRECVNCGAMSTPLWRKDGTGHYLCNACGLYHKMNGINRPLKPQKRLSSSRRAGLCCTNCHTTNTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNITKGKTSTGSTTSATNSPSSITNSDSTVTLKSEPSTTSQYPGQGIVSVSQAQSQSDEALAGGEFKFEPEDYPFSPSSMAPQPGLSVPLRQDSWCALALA
Protein: Cilia- and flagella-associated protein 70 (Tetratricopeptide repeat protein 18) (TPR repeat protein 18) (D3YVL2)
Organism: Mus musculus (Mouse)
Function: Axoneme-binding protein that plays a role in the regulation of ciliary motility and cilium length.
Subcellular location: Cell projection, cilium, flagellum {ECO:0000269|PubMed:30158508}. Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000250|UniProtKB:Q5T0N1}. Cell projection, cilium {ECO:0000269|PubMed:30158508}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:30158508}. Note=Present all along the flagellum, with a marked signal at the base of the flagellum. {ECO:0000250|UniProtKB:Q5T0N1}.
Interaction partners:
- Dynein axonemal heavy chain 2
- Dynein, axonemal, heavy chain 6
- Dynein axonemal heavy chain 17
- Dynein axonemal heavy chain 1
- WD repeat-containing protein 90
- Dynein, axonemal, heavy chain 10
- Dynein axonemal intermediate chain 2
- Dynein axonemal heavy chain 8
- Dynein axonemal heavy chain 12
- Dynein axonemal intermediate chain 1
Sequence:
MDQTSSTTKIVHITVTNGYDLKGFKGDTPVTFVRAEFNQTVLGDSSKVTVSPEGTAKYNFTSNIDLSPDGGGALDDLAHKPLFLTVTEVLPKEKKQKDEKTLILGQAVVDLLPLLEGEESFETTVPLHPVPGSPLETPLPGSKQCSLDVKVFVAEPLLTPAQVSASNLLKVTLEAAYSVPESFIPVGPQQNYMVGLQVPSVGEKDYTMIFKNGNLKLGGEKEPVPRPKKWPIANILAPGASNIPDEFIVGGPYEEEEGELNHPEDREFRNQAECTKKRIVWDLESRCFLHPFAVASFQKRIADCRLWPVEITRVPLVVMPKAKPGKLEKIDDENQLSFHGVAYINMVPLLYPGVKKIRGAFHVYPYLDGTVFEKTKCLFSLFRDTGHHLVQNNKAGGLNSPLSKPLSKNLKEEKPGKDKDTEGRPRLGELQAPSIKSQSSDTPLESEAPLSHNLEGQQYIEAGTYIVLEIQLEKALVPKRMPEELARRVKEMIPPRPPLTRRTGGAQKAVSDYHTQIKSISRAILNEYYRMFGKQGPKLESDIDNETMEERKCQLNYELNCSGKYFAFKEQLKHAVVKIVREKYLKTTAFESQEELQTFISELYVFLVDQMHVALNQAVPDDVPSSTSTIQTSSEQLRLFAFEAEVNEKFEIAAMYYEERLVREPQNLENWLDYGAFCLLTEDNIKAQECFRKALSLNESHVDSLLLCGVLAILLENYEQAEIFFEDATCLEPTNVIAWTLLGLFYEIQNNDIRMEMAFHEAFKQLQARTLQTKLKSTVTIENMEEGVKVEPSFGPWGVVQESTTAIKTEGLSGMRPQSSHQLSPHTNMELHPQPQGPNTALSSLDEFLEESPKAQSESQEPMATGQPLEPSLVQRSSNALLKELTSKKDISKCQDSSAFSPPTQHVIAQPPVTIFMETIRFLMKVNAVQFVHRVLAHELLCPQGGPSCEYYLVLAQTHLLKKDFAKTEEYLQQAAQMDYLNPNVWGVKGHLYFLSGNHAEAKECYERTISFVVDASEMHFIFLRLGHIYLEEKEYENAKRTYMHACKRSPSCLTWLGLGIACYRLEELTEAEDALSEANALNNCNAEVWAYLALVCLKVGRQLEAEQAYKYTIKLKLKDQALLEEIHTVQEMVGFGNPSF
Protein: SWI/SNF and RSC complexes subunit ssr3 (Q9P7S3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- SWI/SNF chromatin-remodeling complex subunit snf5
- SWI/SNF and RSC complexes subunit ssr2
- Chromatin structure-remodeling complex subunit sfh1
- SWI/SNF and RSC complexes subunit ssr1
- Chromatin structure-remodeling complex subunit snf21
- Chromatin structure-remodeling complex subunit rsc7
- SWI/SNF and RSC complexes subunit arp42
- Chromatin structure-remodeling complex subunit rsc1
- SWI/SNF chromatin-remodeling complex subunit snf22
- SWI/SNF and RSC complexes subunit arp9
Sequence:
MSNNSRLPENGVQSGNGEDAELKKSMRIIEREIPDSLLEKIPEAEDYIALQDLERKLDSLIVRKRFDLQDSLSRNSHKTRILRMYIHSTVANQSWQQKGENQENNSGDINSLPIPEWTLHIEGRLLVNPDDEDDKAFELAPFTNFFRKIAIQILRSDDLYPSGNYVEWNKLPDNSNTSNGITVTRKGDQSVDVKIMLYPEEHPERYKLSKAFANILGIREGTRPDIVSYLWQYIKFHRLQDMEEKRLINCDKALRDLFEADRLYFPRIPELMNRFLEPIDPIVIPYTINVSEHTVEKVTIFDIRINTEDPRHSQIRSFLATMMSQDKIRSIDDKLTELIQAITYSQSKYDFMKKFSESPIEFINEWIESQSRDLEIVLDGTNMNYAEKRSADYYQQPWVHESAFHYLNLLNSKKQQSVLNASAKK
Protein: Dipeptidase (EC 3.4.13.19) (Q8G6Z9)
Organism: Bifidobacterium longum (strain NCC 2705)
Function: Hydrolyzes a wide range of dipeptides. Highest activity against Ala-Gln.
Interaction partners:
Sequence:
MACTTILVGKDASYDGSTIIARNEDSANGEFNPKRFIVVKPEEQPREYKSVISHLTITLPDDPLQYTAVPNADLKEGIWGEAGVNEANVAMSATETLTTNERVLGADPFVEYTPAKGDEPEVPGGIGEEDFLTIVLPYVKTAREGVQRLGALLEEFGTYEMNGVAFSDSNEIWWLETVGGHHWIAKRVPDEAYVTMPNQLGIDEFDLEDALGDQEAHMCSEDLAEFIETNHLDLAVENTTPFNPRDAFGSHSDSDHVYNTPRAWYMQRFLNPYDEVWDGPDADHKPTSDDIPWARQPERKVTIEDIKYVLSSHYQGTPFDPYGQLGDERTRHMYRTIGINRQSQLAVMQIRPYRPQASRAIQWMAYGSNPFNTLVPFFPNVDTTPAYLEDTTTRVTSENFYWANRIIAALCDGAFRSTSNAVERYQEKTGAMGHRLVAATDEQIARLGLTAAEEAAQSAAEEEFEADNVDGDVQPMTPDETIAALRNPEVREILAAANQTMADQLKEETEKLLDSVLYTRSMEMKNGFHMSDF
Protein: Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2'] (Q0ZME7)
Organism: Human coronavirus HKU1 (isolate N5) (HCoV-HKU1)
Function: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection.
Subcellular location: Virion membrane {ECO:0000255|HAMAP-Rule:MF_04099}; Single-pass type I membrane protein {ECO:0000255|HAMAP-Rule:MF_04099}. Host endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000255|HAMAP-Rule:MF_04099}; Single-pass type I membrane protein {ECO:0000255|HAMAP-Rule:MF_04099}. Host cell membrane {ECO:0000255|HAMAP-Rule:MF_04099}; Single-pass type I membrane protein {ECO:0000255|HAMAP-Rule:MF_04099}. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers are transported to the host plasma membrane, where they may mediate cell-cell fusion. {ECO:0000255|HAMAP-Rule:MF_04099}.
Interaction partners:
Sequence:
MFLIIFILPTTLAVIGDFNCTNSFINDYNKTIPRISEDVVDVSLGLGTYYVLNRVYLNTTLLFTGYFPKSGANFRDLALKGSIYLSTLWYKPPFLSDFNNGIFSKVKNTKLYVNNTLYSEFSTIVIGSVFVNTSYTIVVQPHNGILEITACQYTMCEYPHTVCKSKGSIRNESWHIDSSEPLCLFKKNFTYNVSADWLYFHFYQERGVFYAYYADVGMPTTFLFSLYLGTILSHYYVMPLTCNAISSNTDNETLEYWVTPLSRRQYLLNFDEHGVITNAVDCSSSFLSEIQCKTQSFAPNTGVYDLSGFTVKPVATVYRRIPNLPDCDIDNWLNNVSVPSPLNWERRIFSNCNFNLSTLLRLVHVDSFSCNNLDKSKIFGSCFNSITVDKFAIPNRRRDDLQLGSSGFLQSSNYKIDISSSSCQLYYSLPLVNVTINNFNPSSWNRRYGFGSFNLSSYDVVYSDHCFSVNSDFCPCADPSVVNSCAKSKPPSAICPAGTKYRHCDLDTTLYVKNWCRCSCLPDPISTYSPNTCPQKKVVVGIGEHCPGLGINEEKCGTQLNHSSCFCSPDAFLGWSFDSCISNNRCNIFSNFIFNGINSGTTCSNDLLYSNTEISTGVCVNYDLYGITGQGIFKEVSAAYYNNWQNLLYDSNGNIIGFKDFLTNKTYTILPCYSGRVSAAFYQNSSSPALLYRNLKCSYVLNNISFISQPFYFDSYLGCVLNAVNLTSYSVSSCDLRMGSGFCIDYALPSSRRKRRGISSPYRFVTFEPFNVSFVNDSVETVGGLFEIQIPTNFTIAGHEEFIQTSSPKVTIDCSAFVCSNYAACHDLLSEYGTFCDNINSILNEVNDLLDITQLQVANALMQGVTLSSNLNTNLHSDVDNIDFKSLLGCLGSQCGSSSRSLLEDLLFNKVKLSDVGFVEAYNNCTGGSEIRDLLCVQSFNGIKVLPPILSETQISGYTTAATVAAMFPPWSAAAGVPFSLNVQYRINGLGVTMDVLNKNQKLIANAFNKALLSIQNGFTATNSALAKIQSVVNANAQALNSLLQQLFNKFGAISSSLQEILSRLDNLEAQVQIDRLINGRLTALNAYVSQQLSDITLIKAGASRAIEKVNECVKSQSPRINFCGNGNHILSLVQNAPYGLLFIHFSYKPTSFKTVLVSPGLCLSGDRGIAPKQGYFIKQNDSWMFTGSSYYYPEPISDKNVVFMNSCSVNFTKAPFIYLNNSIPNLSDFEAELSLWFKNHTSIAPNLTFNSHINATFLDLYYEMNVIQESIKSLNSSFINLKEIGTYEMYVKWPWYIWLLIVILFIIFLMILFFICCCTGCGSACFSKCHNCCDEYGGHNDFVIKASHDD
Protein: Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (Q7ZVW7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR038189}.
Interaction partners:
Sequence:
MSDVTPNTPVRKLRYSALRALADLLDPQDTWRSIMADISRPCGEPRYTQMHMRRFEACVLQGKSPTMELLFDWGTSDCTVGDLVEILIRHQLFAAVTVLLPDHSVCHAHTGSVWCEEAAPASAVCLQACEITQTVEDNSNKPQKISKPVEDDSNKPVQEQELFVEPDSSSGAQESSWDSSQGFHTFSLHELTAMTQHWDERPLSDGGCRLGSGGFGVVFRGRMGDKHVAVKKLNPLDGSSYEDLRKQFNQEIQTLRSLSHENVLRVLGCSCSGPPLCVVFELMVNGSLLERLACAEHTPALTWRNRCWITVGAARGLSYLHTHAHIHRDVKSANILLDEGFVAKISDFGLTRSAAAGAAGGFVWASSSGRESGSCTVAGDEG
Protein: Uncharacterized protein Rv2929 (P9WL13)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Thioesterase TesA
Sequence:
MIELSYAPDVAGRRSNWPKGSGVNTWTAIRWTFAEDSPYVGTGLERMASDTHGGGGGRPVTPPPPGMHHLGCSRGVLLISSQRDAGHKTCDPAAGGTLTSVLT
Protein: Copper ion binding protein (Q0WTS1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Phosphoglycerate mutase family protein
- UDP-glycosyltransferase 76C5
- Leucine-rich repeat
- Large ribosomal subunit protein bL21m
- Insecticidal crystal toxin domain-containing protein
- Expressed protein
- Glycine-rich protein 3 short isoform
- Staphylococcal-like nuclease CAN2
- Non-specific lipid transfer protein GPI-anchored 13
- Receptor-like protein kinase At5g59670
Sequence:
MVGGGNRRDEGSMPIQNTNLFAALDTSRKKKKSDKAGKSKASSKREDSQKEPEPQVFWAPTPLKAKAWADIDSDDEDDDYYATTAPPQSLWSTSEASHSDAKDVPAEEIESEEDTLDDGDDDDVEEDHEQGTETQVHPEAEPEVKKAPEVRAPPKEAERQLSKKERKKKELAELEALLADFGVATKDENGQQDSQDKGEKKEVNDEGEKKENTTGESKASKKKKKKDKQKELKESQSEVKSNSDAASESAEQEESSSSIDVKERLKKIASMKKKKSSKEVDGASTAAAKEAAARKAKLAAAKKKEKKNYNQQPVR
Protein: FI16517p1 (Translin associated factor X, isoform B) (Translin associated factor X, isoform C) (Trax) (Q9VF77)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Translin
- Protein argonaute-1
Sequence:
MPKNGGAGHRNTAPRKRQIPAAQLDEDSPIVQQFRIYSNELIMKHDRHERIVKLSRDITIESKRIIFLLHSIDSRKQNKEKVLEEARQRLNKLIAVNFRAVALELRDQDVYQFRSSYSPGLQEFIEAYTYMEYLCHEDAEGENETKSVSDWQAIQAVMQYVEESSQPKEEPTEGEDVQAIAQVESPKKFQFFVDPTEYILGLSDLTGELMRRCINSLGSGDTDTCLDTCKALQHFYSGYISLNCQRARELWRKITTMKQSVLKAENVCYNVKVRGGEAAKWGATFDQKPADEVDEGFY
Protein: Growth hormone (Q0QBC4)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLPLAFTLLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKESERSYIPEGQRYSIQNTQVALCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF