Protein: DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (D3ZTN0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- X-ray repair cross-complementing protein 5
- X-ray repair cross-complementing protein 6
- Non-homologous end-joining factor 1
- Protein artemis
- DNA ligase
- Cellular tumor antigen p53
- DNA repair protein XRCC1
- Breast cancer type 1 susceptibility protein homolog
- PAXX, non-homologous end joining factor
- TP53-binding protein 1
Sequence:
MADPGAGLRCWLLQLQEFVSAADRYNAAGASYQLIRGLGQECVLSTCSAVQALQISLVFSKEFGLLVFIRKSLSIDEFRDCREEALKFLCVFLEKIDQKVLHYSFDIKNTCISVYTKDRTAKCKIPALDLLIKLLKILRSSRVMDEFKIGELFNKFYGELVSKSKLPDTVLEKVYELLGVLGEVHPSEMVNHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEEDPQTSKEIFGFTLKAIRPQIEMKRYAVPLAGLRLLTLHASQFTTCLLDNYITLFEVLSKWCNHTNVELKKAAHSALESFLKQISFTVAEDAELHKSKLKYFMEQFYGIIRNADSNNKDLAIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDATEDHVYQMPSFLQSIASVLLYLDTVPEVYTPVLEHLMVVQIDSFPQYSPKMQLVCCKALVKVFLSLTEKGPVHWNCISAVVHQGLIRICSKPVVLQKDVESRSENRWASEEVRMGRWKVPTYKDYVDLFQNLLGCDQMADFILGDETFLFVNSSLKSLNHLLYDEFIRSVLKIVEKLDLTLEKQTTGEQEDERTADVWVIPTSDPAANLHPIKPNDFSAFINLVEFCREILPKKQVSFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGVSPKCLKHSPENTEKHSCFALFAKFGKEVSVKMKQYKDELLASCLTFVLSLPPDIIKLDVRAYVPALQMAFKLGLSHLPLAEIGLHALKEWSVHIDKSIMQPYYKDIVPCLDGYLNTSTLSDETKSHWEVSALSRAARKGFNRDVVKLLKRTRNVTSDEALSLEEIRIRVVQILGSLGGQINKNLITATSGERMKKYVAWDREKRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVMFMLGRATQMPEGQGLPPMYQLYKHMFPVLLKLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDPVDSTLRDFCGQCVQEFLKWSIKQTTPQQQEKSPVNSKSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEGSLVEQFVFEALVTYMESLALAHADEKSLGTIQQCCDAIDHLRRIIEKKYISLNKAKKRRLPRGFPPLTSLCLLDLVKWLFAHCGRPQTECRHKSIELFYKFVPLLPGNKSPSLWLRDLIKAEGISFLINTFEGGASSSGQPSGILAQPTLLHLQGPVSLRGMLQWLDHLLAALECYNTFIEEKTVQVQEVLGTEVQSSLLKSVAFFLESIATCDARTVEQRFGTGLTGPPSVQEEEKYNYSKCTVLVRIMEFTTTLLVTFPEDCKLLEKDLCNTKLMKVLVKMLCEPLSIGFNIGDVQVMNHLPSICVNLLKALRKSPYRDKLETHLKEKVTAQSVEELCAINLCSSAACQERTKLLSLLSACKQLHKAGFSHIISASQSTALNHSIGMRLLSLVYNGIAPAQEKQYLQSLDPSCKSLASGLLELAFAFGGLCEHLVSLLLNSSMLSTQYLGSSQRNISFSHGEYFYSLFPEVINTELLKSLDVTVSRLLESSSDNPKMVSTILNGMLDMSFRDRAVQKHQGLKLATAILQNWRKCDSWWAPDSAPESKTTVLSLLAKMLQIDSTLSFDTNHSSFSEIFTTYANLLADTKLGLHLKGQAVILLPFFTRVTEDRLGDLKHILEKFIVLNFPMKSDEFPPDSLKYNNYVDCMKKFLDALELSQSPMLLQLMTDILCREQQHIMEELFQTTFKRIARRSPCVTQLNLLESVYTMFRKGGLLSDVTQAFVDRSLLTLLWHCDLDTLKEFFSRIVVEAIDVLKSRFTKLNDTFDTQITKKMCYYKMLAVMYSRLLKDDVHSKESKINQAFQGSCVAEGNELTKTLLKLCHDAFTENMAGESQLLEKRRLYHCAAYNCAISLISRVFNELKFYQGFLFSEKPEKNLFIFENLIDLKRCYTFPIEVEVPMERKKKYVEIRKEARDAANGASGNPRYMSSLSYLTESSLSEEMSQFDFSTGVQSYSYSSQDRKPTTGHFQRREHQDSMAQDDIIELEMDELNQHECMAPMTSLIKHMQRNVIAPKGQEGSISKDLPPWMKFLHDKLENASVSLNIRLFLAKLVINTEEVFRPYAKHWLGPLLQLAVCENIGEGIHYMIVEIVATILSWTGLATPTGVPKYEVLANRLLYFLMKYVFHPKRAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSNKDPNSKDNSVGIQLLGIVVANNLPPYDLKGDITSAMYFEALVNNMSFVKYKEVYAAAAEVLGLILQHVTERKHVIAESVYELVVKQLKQHQNTMEDKFIVCLNKIVKGFPPLADRFLNALFFLLPKFHGVMKTLCLEVVLCRAEAITGLYLQLKSKDFLQVMRHRDDERQKVCLDIIYKMVAKLKPTELRELLNPVVEFVSHPSPTCREQMYNILMWIHDNYRDPESQMDEDSQEIFKLAKDVLIQGLIDENLGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTRMSPDYLNPIFEHPLSECEFQEYTIDPDWRFRSTVLTPMFIETQAFPSTLNTQTQEGSPSDRRQKPGQVRATQQQYDFTPTQTSVERSSFDWLTGSSIDLMADHTVFSSESLSSSLLFSHKKSEKSQRVSWKSVGPDFGTKKLGLPGDEVDNQVKSGTHSQTEILRLRRRFLKDQEKLSLLYAKRGLMEQKLEKDIKSELKMKQDAQVVLYRSYRHGDLPDIQIQHSSLITPLQAVAQKDPIIAKQLFSSLFSGILKEMHKFRTTSEKNIIIQNLLQDFNRFLNTTFLFFPPFVSCIQEISCQHVDLLTLDPAAVRVGCLASLQQPGGIRLLEEALLHLLPKEPPTKRIRGKTCLPPDVLRWMELAKLYRSIGEYDVLHGIFSSELGTKQDTQNALLAEARSDYFQAANLYKEALNKLEWLDGEPTEAEKEFWEMASLDCYNNLSQWKELEYRSTVNIGSENSLDLSKMWSKPFYQETYLPYVIRSKLKLLLQGEDNQSLLTFVDEAMHKELQQMVLELQYSQELSLLYILQDDIDRATYYIKNAIQIFMQNYSSIDVLLYRSRLAKLQSVQTLAEIEEFLNFIRKHGDLSSLGPLRRLLKTWTSRYPDTVTDPMHIWDDIITNRCFFLSKIEERLTVSPGDHSMSVDEDEDSFAREGSEPKEDAHHILQSCRFTMKMKMIESSWKQNNFSLSMKLLKEMHKESKIRESWRMQWIHSFCQLNHCRSHTQSPQEQVLTMLKTITLLDESDISNYLNKNIQAFCDQNILLGTSCRIMADALSREPACLSGLEKSKTESIFALSGSNTENTERVISGLYQRAFHHLSMAVQSAEEETQLSCWGHEAAAERAHAYMTLVGFCDQQLRKVEESASTASQKISTELEGYPALVVEKMLRALKLNSSEARLKFPRLLQIIEQYPEETVNIIIKEISSIPCWQFIGWIGHMVALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFQNTSSGHNNKAFVERIKSKLDQGGVIQGFINALDQLSNPDMLFKDWVNDTKDELGKNPVNKKNIEKLYERMYAALGDFRAPGLGPFRRKFIQTFGKEFVKSFGNGGSKLLTMKLDEFRNITDSLFVRMRKDSKLPGNLKEYSPWMSEFTVKSELEIPGQYDGKSKPLPEYHVRISGFDERVKVMVSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQLFEVMNAILSQDAACSQRNMQLRTYRVVPMTSRLGLIEWIENTMTLKDLLLSNMSQEEKVAYDSDSKAPIYDYRDWLIKVSGRSDVKGYTLMYSRANRTETVTAFRRRENKVPADLLKRAFVKMSTSPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQFLPIPELMPFRLTRQFISLMLPMKETGLVCTVMVHALRAFRSCAGLLTDTMEVFVKEPSFDWKGFEQTMLRKGGSWIQEINVTEKNWYPQHKIRYAKRKLAGANPAVITCDELRLGHEASPAFRSYVAVARGNKDYNIRAQEPESRLSEETQVKCLVDQATDPNILGRTWEGWEPWM