wanglab/gogpt-training-data huggingface dataset:
Protein: Meiotic recombination protein REC8 homolog (Cohesin Rec8p) (O95072)
Organism: Homo sapiens (Human)
Function: Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q6AYJ4}. Chromosome {ECO:0000250|UniProtKB:Q6AYJ4}. Chromosome, centromere {ECO:0000250|UniProtKB:Q6AYJ4}. Note=In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II. Localized to centromeres and spindle poles in endopolyploid tumor cells. {ECO:0000250|UniProtKB:Q6AYJ4}.
Interaction partners:
- Structural maintenance of chromosomes protein 3
- Cohesin subunit SA-3
- Structural maintenance of chromosomes protein 1B
- Structural maintenance of chromosomes protein 1A
- Cohesin subunit SA-1
- Separin
- Cohesin subunit SA-2
- Shugoshin 2
- Double-strand-break repair protein rad21-like protein 1
- Sister chromatid cohesion protein PDS5 homolog A
Sequence:
MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLIQPGPRFH
Protein: Transcription factor TT2 (Myb-related protein 123) (AtMYB123) (Myb-related transcription factor LBM2-like) (Protein TRANSPARENT TESTA 2) (Q9FJA2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS).
Subcellular location: Nucleus.
Interaction partners:
- Protein TRANSPARENT TESTA GLABRA 1
- Transcription factor TT8
- Transcription factor GLABRA 3
- Protein TRANSPARENT TESTA 1
- Transcription factor EGL1
- Dihydroflavonol 4-reductase
- Protein TORMOZ EMBRYO DEFECTIVE
- Anthocyanidin reductase
- WRKY transcription factor 44
- Protein DETOXIFICATION 41
Sequence:
MGKRATTSVRREELNRGAWTDHEDKILRDYITTHGEGKWSTLPNQAGLKRCGKSCRLRWKNYLRPGIKRGNISSDEEELIIRLHNLLGNRWSLIAGRLPGRTDNEIKNHWNSNLRKRLPKTQTKQPKRIKHSTNNENNVCVIRTKAIRCSKTLLFSDLSLQKKSSTSPLPLKEQEMDQGGSSLMGDLEFDFDRIHSEFHFPDLMDFDGLDCGNVTSLVSSNEILGELVPAQGNLDLNRPFTSCHHRGDDEDWLRDFTC
Protein: Zinc-type alcohol dehydrogenase-like protein C2E1P3.01 (EC 1.-.-.-) (Q9P7F4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Zinc-type alcohol dehydrogenase-like protein C16A3.02c
- Putative S-
- Aldo-keto reductase yakc [NADP
- Uncharacterized oxidoreductase C8E4.04
- Glucose-6-phosphate 1-dehydrogenase
- Uncharacterized oxidoreductase P32A8.02
- Uncharacterized oxidoreductase C215.11c
- NAD/NADP-dependent indole-3-acetaldehyde reductase
- Zinc-type alcohol dehydrogenase-like protein C337.11
Sequence:
MKAVIADGQNGVEVISDAPKPTPEKGEFLGRVIRVAFNPIDWKTLYNASIEKGTVGGTDFVAVVEDVGEGVDRSKYIGATVSGWAPGPLDGSNAAWREYITLDVNLVYFVPKNITPSQAATLPLTFTTASQGLNQYLGLPLPPTDGSKNSAQQKWVLVWSGSSSVGQYVVQLAHHAGYKVIATCSPHNFDWIKKLGADFTVDYHDPNVVEIIKKATDDSVFYGFDAASFPETSTLAVKAFSSKVKDGKLINILSSPPSPRSEVKIIGIIDYSLFNREFNFFGNKIEPIQASYDHAVEVYKKLTGWLQEGVIIPNRVKEFDGGLQAIPKALREFASGKHSAVKFVVRID
Protein: mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (G5EB26)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- MAP kinase kinase
- MAPKKK cascade protein kinase regulator Ste50
- mitogen-activated protein kinase kinase
- High osmolarity signaling protein sho1
- Serine/threonine-protein kinase ste20
- non-specific serine/threonine protein kinase
- Mitogen-activated protein kinase
- Mitogen-activated protein kinase kinae mkk2
- Cytoplasmic response regulator
- GTP binding protein
Sequence:
MLTSKAYAGPLGLPSSQTPTASYHTTTQKSSTFSESQTGTVYTSPTKSEFSEADDGLDAVRSWDENQVISWLHSINCQQYEPLFRANNFNGNNLIECDQKILQEMGIKKIGDRVRIFVAIKQLRNKSVVNKKQKNLRQLAALEAAHQQASPDSARSYSARQQTSSAGHASRTGDYSYGRPTSRPGSPLRPHRYVANSPMDSGRKDYLSAGSGAGRNPGTPVERIGTHSRQNPSLDGMTMGSLLSNAPVIRVIYSGGQTKVLDIKHCKTPDEIILCVLKKLQLPEHQYRNYCFYVLDGLDPDPSNCRRLSDHELMEICEGFHRSERGRLILRKIHAGEPDAEEVHRAAQLALDESQQAHMNALSSSNARNQMKIQQLTGESWHNIRQPMSPVSSRHNTTPSDHEIRPPQVSERVSKLRSFFGARPPSEMIIHEISSYFPGHQREDIEKTMRMSVRRSQRLSRAASRLSVVSNTSYASSLRDAPPIPSIADTWLNNGTPPTRAARPLSVLSTRPGLPSTSYRDSIASSSLHPLQEESPVEPNRKSYVSFDSGSDDPNNSRHSLLDENASVAATDGGSFNERLSVLVAEDGEEEDDGLAEFLAGNNFVNWMKGSLIGEGSFGSVFLALHSITGELMAVKQVEIPSATKGTEFDKRKNSMVEALKHEIDLLQGLHHPNIVQYLGTTADDQYLNIFLEYVPGGSIATMLKQYNTFQEPLIKNFVRQILAGLSYLHSKDIIHRDIKGANVLVDNKGGIKISDFGISKRVEASTVLGSRASNGGGHIHRPSLQGSVYWMAPEVVRQTAHTKKADIWSLGCLVIEMFIGSHPFPDCSQLQAIFAIGSNKARPPAPEHASKDAVAFLDMTFQLDHEKRPDADELLKSPFLATTLT
Protein: Phosphoribosyltransferase domain-containing protein 1 (Q9NRG1)
Organism: Homo sapiens (Human)
Function: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
Interaction partners:
- Adenylosuccinate lyase
- Ribonucleoside-diphosphate reductase large subunit
- Hypoxanthine-guanine phosphoribosyltransferase
- ATP synthase F
- ATP synthase F
- ATP synthase F
- Protein-lysine N-methyltransferase EEF2KMT
- S-methyl-5'-thioadenosine phosphorylase
- Purine nucleoside phosphorylase
- WD repeat-containing protein 90
Sequence:
MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDIMKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGEMQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDGFRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV
Protein: Uncharacterized protein Rv3776 (P72042)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- HNH nuclease domain-containing protein
- Uncharacterized protein Rv1702cMb1728c
- HNH nuclease domain-containing protein
- Uncharacterized protein Rv2100
- Uncharacterized protein Rv1148c
- HNH nuclease domain-containing protein
- HNH nuclease domain-containing protein
- Uncharacterized protein Rv1945
- HNH nuclease domain-containing protein
- Uncharacterized protein Rv1128c
Sequence:
MFEISLSDPVELRDADDAALLAAIEDCARAEVAAGARRLSAIAELTSRRTGNDQRADWACDGWDCAAAEVAAALTVSHRKASGQMHLSLTLNRLPQVAALFLAGQLSARLVSIIAWRTYLVRDPEALSLLDAALAKHATAWGPLSAPKLEKAIDSWIDRYDPAALRRTRISARSRDLCIGDPDEDAGTAALWGRLFATDAAMLDKRLTQLAHGVCDDDPRTIAQRRADALGALAAGADRLTCGCGNSDCPSSAGNHRQATGVVIHVVADAAALGAAPDPRLSGPEPALAPEAPATPAVKPPAALISGGGVVPAPLLAELIRGGAALSRMRHPGDLRSEPHYRPSAKLAEFVRIRDMTCRFPGCDQPTEFCDIDHTLPYPLGPTHPSNLKCLCRKHHLLKTFWTGWRDVQLPDGTIIWTAPNGHTYTTHPDSRIFLPSWHTTTAALPPAPSPPAIGPTHTLLMPRRRRTRAAELAHRIKRERAHVTQRNKPPPSGGDTAVAEGFEPPDGVSRLSLSRRVH
Protein: Adiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II) (Q86V24)
Organism: Homo sapiens (Human)
Function: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:25855295}; Multi-pass membrane protein {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:25855295}. Note=Localized to the cell membrane and intracellular organelles. {ECO:0000269|PubMed:12802337}.
Interaction partners:
- Adiponectin
- DCC-interacting protein 13-alpha
- Adiponectin receptor protein 1
- Peroxisome proliferator-activated receptor alpha
- Leptin
- Cadherin-13
- Resistin
- Nicotinamide phosphoribosyltransferase
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Insulin
Sequence:
MNEPTENRLGCSRTPEPDIRLRKGHQLDGTRRGDNDSHQGDLEPILEASVLSSHHKKSSEEHEYSDEAPQEDEGFMGMSPLLQAHHAMEKMEEFVCKVWEGRWRVIPHDVLPDWLKDNDFLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGCVFFLCLGIFYMFRPNISFVAPLQEKVVFGLFFLGAILCLSFSWLFHTVYCHSEGVSRLFSKLDYSGIALLIMGSFVPWLYYSFYCNPQPCFIYLIVICVLGIAAIIVSQWDMFATPQYRGVRAGVFLGLGLSGIIPTLHYVISEGFLKAATIGQIGWLMLMASLYITGAALYAARIPERFFPGKCDIWFHSHQLFHIFVVAGAFVHFHGVSNLQEFRFMIGGGCSEEDAL
Protein: Transcription factor RAX2 (Myb-related protein 38) (AtMYB38) (Protein REGULATOR OF AXILLARY MERISTEMS 2) (Q9SJL7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator (By similarity). Positively regulates axillary meristems (AMs) formation and development, especially during inflorescence.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
- Transcription factor bHLH153
Sequence:
MGRAPCCDKANVKRGPWSPEEDAKLKDYIEKQGTGGNWIALPHKAGLRRCGKSCRLRWLNYLRPNIRHGDFTEEEDNIIYSLFASIGSRWSVIAAHLQGRTDNDIKNYWNTKLKKKLIATMAPPPHHHLAIATSSSSASPSSSSHYNMINSLLPYNPSTNQLLTPHQGIMMTMMGQQQQLFYQEDMGNLVNSPNRNNLIMSHQEDNQEQSTNKGIMLLSDVRSGSSTTSTVTRVKMEHRDHDDHHHHHEEDERSMTSVVMEDYGMEEIKQLISSSCTSSNNSLWFDENKTEDKFMLYY
Protein: Abl interactor homolog (Q55FT9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in regulation of actin and microtubule organization. Required for proper cytokinesis.
Interaction partners:
- Protein SCAR
- Nck-associated protein 1 homolog
- Protein pirA
- Protein BRICK1
- Uncharacterized protein
- Actin-related protein 2/3 complex subunit 3
Sequence:
MSESIDINVYSQTTIPNAMAELMDNHNKMEQISAYCKSLYANGDAAQAYEQTQGYAKNALLNVAYHIQTVGTHITSLLQLQTNEMEKLNIEIQTLTQRVRMIHDSTGTNVFSNQDAAKPYKSSLKNRKVDTEATKAPVKYVHKPISYGISASDINQNGVPPPLNHSNSSANLTSSSGHLAASSTSNSSTPSYQSPSYSSQPTISSGTPPPIQKQPPRVGNAPPPPSLSVPAAPPPPVMNVPPPPPTSQRPSSVNNNAPSNDFPPPPPPSSSSSGGDLPPPPSFGLPPPPTLGDDFPPPPPPPVGSYDFPPPPARPQSQFYDHNDFPPPPPPM
Protein: Z band alternatively spliced PDZ-motif protein 67, isoform H (X2JGI5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MVLDIKMCRFDNVPWGFRLVGGADYDYPLTVVKVTEGSIADEAGLRVEDIIVRINDTAATPLTHDEAHRLIMGSGSVFYFGVYRENEEDAYECLKKFPTSEGSLTKSPMPTISPSPTPSLSQLTETTNARTPEPEPFVPLPRELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEKRGDVNGHDAPGQADEGGLPVENLYLPDLPDRPCSALSERQEIKLVEEEIAAVLSGESEVLKEHNVLGIFPKPGVCMSSDVLRSLNEEVTKTKLEKDKENRQWSTFLQRPNRPVPKSKQSLEAERRAANAYKVTIVKSAPREKSPMPEAKPAPKEATPPKEVEKKEEEPVPEEVVEPEPEPEKDEEPLPTDSEVPNLEQLPETELPDEQPEKSDAPKEVCEPEVVIQTEPGSPDGNEASDGPAGATPPAEPITPVPVKSEEELALERQLADVQRQLAALSSLPSTIQSTLDAVTKQLADLLPTIKLQQQEKQLPQIDENSGNEEQVEEGVTTATNTINTAGETEDAGKDISISGSDNPPVGPCESNEDRCDANDREVAEISRSTDDNRLAKDKKKDLDQEQKQQQQQQQEPLSEEQNFKKQKIAFWNRLFNGEHITRQRFRELQGLGLTMQKVNFMKYQKPERKIDLNRSEVYKYLNPHLDRAPVRGIEVRAPLVAAESDIRQSLQS
Protein: Protein TEM1 (P38987)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: GTP-binding protein involved in termination of M phase. May play a role in triggering the degradation of G2 cyclin to inactivate M-phase promoting factor at the termination of mitosis. Acts upstream of CDC15 kinase and may be required to activate the CDC15 protein kinase pathway.
Interaction partners:
- Cell cycle serine/threonine-protein kinase CDC5/MSD2
- Tyrosine-protein phosphatase CDC14
- Mitotic check point protein BFA1
- Cell division control protein 15
- Guanine nucleotide exchange factor LTE1
- Nucleolar protein NET1
- Cell cycle protein kinase DBF2
- Mitotic check point protein BUB2
- Sporulation-specific protein 12
- Protein SIC1
Sequence:
MATPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQDRKSHNIRKPSSSPSSKAPSPGVNT
Protein: Tight junction protein 3 (D3Z8G7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell junction, tight junction {ECO:0000256|ARBA:ARBA00004435}. Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}.
Interaction partners:
- InaD-like protein
- Occludin
- Claudin-1
- Claudin
- Claudin-7
- Claudin
- Claudin-5
- MARVEL domain containing 2
- Claudin
- Tight junction protein 2
Sequence:
MVADMEELTIWEQHTATLYKDPRRGFGIAVSGGHDRAGGPVVVSDVVPGGPAEGRLQTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANITVKRPRRVQLPATKASPASGHQLSDQEEADHGRGYEGDSSSGSGRSWGERSRRSRAGRRVRMGSHGRRSSCGGSEANGLDLVSGYKRLPKQDVLMRPLKSVLVKRRNSEEFGVKLGSQIFIKHITESGLAARNRGLQEGDLILQINGVSSANLSLSDTRRLIEKSEGQLTLLVLRDSGQFLVNIPPAVSDSDSSLMEDISDLTSELSQAPPSHIPPPPLKSRRSPEDSQTDSPVETPQPQRRERSVDSRAIAEPESPGESRYDIYRVPSRQSLEDRGYSPDTRVVRFPKGVSIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNDMPFRNLTREEAVQFLLGLPAGEDVELVIQSKQDIFRKMVQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYRGSGSGHGHSSHGGLWLAARMGRDLREQERGVIPNQSRAEQLASLEAAQRAAGLGPGASTGSNPRAEFWRLRGLRRGAKKTMTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKRLTTEVPEQFEIAESVSRTDSPSKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPVVIFCAPESRSALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTATIPLNGTSDSWYQEVKAVIQQQQARPIWTAEDQLNGSSEDLDLPGHGLAASSGDLSCDSRANSDYEDTDGEGTYTDREGEPQDFDEEAPPTALARSSEPVWVDDHQGLMGHGRIAAAEVQADSHYTPDQRRQDSMRTYKHEALRKKFTRARDIESSDEEGYDWGPATDL
Protein: P2X purinoceptor 2 (P2X2) (ATP receptor) (Purinergic receptor) (Q9UBL9)
Organism: Homo sapiens (Human)
Function: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
Subcellular location: Cell membrane {ECO:0000269|PubMed:23345450, ECO:0000269|PubMed:31636190}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P56373}. Note=Localizes to the apical membranes of hair cells in the organ of Corti. {ECO:0000269|PubMed:23345450}.
Interaction partners:
- P2X purinoceptor 3
- P2X purinoceptor 6
- P2X purinoceptor 5
- P2X purinoceptor 4
- P2X purinoceptor 1
- P2Y purinoceptor 6
- P2Y purinoceptor 4
- P2X purinoceptor 7
- P2Y purinoceptor 2
- P2Y purinoceptor 11
Sequence:
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Protein: Glycoside hydrolase family 15, cellulose signaling associated protein envoy (G0RUC2)
Organism: Hypocrea jecorina (strain QM6a) (Trichoderma reesei)
Interaction partners:
Sequence:
MLEAPIMVSSGSSDLPLQLNPWEAQALNYGFPQEPSTNGHAGSNSNNNNNTPAWIQLPDPIIYPGIYSASGIDVMGILLRIASRPNPTIDLGPLDCSVSLTLCDISLPDAPIVYASPGFYQLTGYSAPEIMGRNCRFLQNSPHMPPPGRVSDAVQEMRRAIRAHQEVQVRIVNYKKNGTPFTNVVTILPLWADPSGHHFAVGLQAEL
Protein: Transcription factor bHLH93 (Basic helix-loop-helix protein 93) (AtbHLH93) (bHLH 93) (Transcription factor EN 47) (bHLH transcription factor bHLH093) (Q9LSL1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. May be involved in the differentiation of stomatal guard cells.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor bHLH130
- Dof zinc finger protein DOF4.6
- Transcription factor FAMA
- Transcription factor bHLH79
Sequence:
MELSTQMNVFEELLVPTKQETTDNNINNLSFNGGFDHHHHQFFPNGYNIDYLCFNNEEEDENTLLYPSSFMDLISQPPPLLLHQPPPLQPLSPPLSSSATAGATFDYPFLEALQEIIDSSSSSPPLILQNGQEENFNNPMSYPSPLMESDQSKSFSVGYCGGETNKKKSKKLEGQPSKNLMAERRRRKRLNDRLSMLRSIVPKISKMDRTSILGDAIDYMKELLDKINKLQDEEQELGNSNNSHHSKLFGDLKDLNANEPLVRNSPKFEIDRRDEDTRVDICCSPKPGLLLSTVNTLETLGLEIEQCVISCFSDFSLQASCSEGAEQRDFITSEDIKQALFRNAGYGGSCL
Protein: ADAM metallopeptidase domain 9 (A0A8I6AAS7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MILHGQSTWTVVDHDSEQTVHLSSYEIVTPWRLSRERREALRPSSKQISYVIQAQGKQHIIHLERNTDLLPNDFVVYTYDEEGSLLSDHPNVQSHCHYRGYVEGVPNSTVAVSACFGLRGLLHLENASFGIEPLHNSSHFEHVFYPMDDVHQEPLRCGVSNRDTEQEATQGEEEEHPSVTQLLRRRRAVLPQTRYVELFIVVDKERYNMMGRNQTAVREEMIRLANYLDSMYIMLNIRIVLVGLEIWTDRNPINIIGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRECFCAAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGSCLLNIPKPDEAYSAPSCGNKLVDPGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCQFLPGGSMCRGKTSECDVPEYCNGSSQFCPPDVFIQNGYPCWNSKAYCYNGVCQYYDAQCQVIFGSKAKAAPRDCFIEVNSKGDRFGNCGVSGSNYKTCATGNALCGKLQCENVQEMPVFGIVPAIIQTPSRGTKCWGVDFQLGSDVPDPGMVNEGTKCDAGKICRNFQCVNASVLNYDCDIQGKCHGHGVCNSNKNCHCEDGWAPPHCDTKGYGGSVDSGPTYNAKSTALRDGLLVFFFLIIPLVAAAFFLFIKRDELRKTFRKKRSQMSDGRNQANASRPPGDPSVSRPPGGPSVSRPPGGPNVSRPPGGPNVSRPPGGPSVSRPPPVHGNRFPVPTYAIKQPPQFPSRPPPPQPKIPSQGNLIPARPAPAPPLYSSLT
Protein: Ovocalyxin-36 (Uncharacterized protein) (Q53HW8)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MKPLKLFGMVVFCGLLSPTQGVLSGLSCAISPRAMQQVLSDAIIQTGLLEKHLQGMALPNIMSDRGLLSSPTIITGLHLERSWLPTLSIALLPGIGMQLVVTVHLDLSGNCLMGILSEVIAISLDVTITSNIKSTSFELGTVHVTVDDCFCILGAVKIKLISGLLSLSVHDMVFSHLTATLPGLLCPVMDAVSEIVNVQLLSTLNVVMPVGLKGMVHYHLVGPPFTSGSSLMMDLDGTVQQMGGSIIPHDSYASTLPPLLDGLLVIILRQSFLSSLLALLLHIQPYTFPCSSEAFSGANQLRDSITDLYPTGCTSCPAASPLSIRVECVGNPILLLEPNKATVELSVLLQVFVKRPDGSVIILLLLKADLSLNVRLSISRGSLMLAFSLSRVSLFLESSDIGISEISNLKPHLTKLLVEIYLPRLNAVAADGIPLPDVFGITLMGAELQILLGLLAISV
Protein: Anthocyanidin reductase ((2S)-flavan-3-ol-forming) (VvANR) (EC 1.3.1.112) (Q5FB34)
Organism: Vitis vinifera (Grape)
Function: Produces the terminal flavan-3-ol monomers required for the formation of proanthocyanidins or condensed tannins in leaves and flowers, as well as in the skin and seeds of developing berries. Behaves as a reductase and as a C-3 epimerase. Catalyzes the double reduction of anthocyanidins, producing a mixture of (2S,3S)- and (2S,3R)-flavan-3-ols (Ref.1). The enzyme catalyzes sequential hydride transfers to C-2 and C-4, respectively and epimerization at C-3 is achieved by tautomerization that occurs between the two hydride transfers. Converts cyanidin, pelargonidin and delphinidin into catechin and epicatechin, afzelechin and epiafzelechin, and gallocatechin and epigallocatechin respectively.
Interaction partners:
Sequence:
MATQHPIGKKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRADLTDELSFEAPIAGCDFVFHVATPVHFASEDPENDMIKPAIQGVVNVMKACTRAKSVKRVILTSSAAAVTINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAAWKFAEENNIDLITVIPTLMAGSSLTSDVPSSIGLAMSLITGNEFLINGMKGMQMLSGSVSIAHVEDVCRAHIFVAEKESASGRYICCAANTSVPELAKFLSKRYPQYKVPTDFGDFPPKSKLIISSEKLVKEGFSFKYGIEEIYDESVEYFKAKGLLQN
Protein: SUPpressor of Rpm-1 (Q95XT1)
Organism: Caenorhabditis elegans
Interaction partners:
- MAP kinase-activated protein kinase mak-2
Sequence:
MKLEDSCAQRNLVLNLLHREIGTQYRKYGSIRNTYRHPYQLIAAVLPDLSAGHSMDRYDPTASPSFSTYAKCLGFSPDGKYMAFHSHARSAISVLRYSGLENFVKDNVDLRTFFKKIDTFQLKRFVRTLNCRLNRVLGSWWTDDSSILIVQLSLNKIYDEDSDQNESDEEQLPQAYDIVNHDADFFANELPSTPSEREASPPSSSQFSNSAAPNLPETKQPPTTTDQYSETSRTIPFYLAMESAATISLDGERVAGETSRTMPVYHSLTASIIDGERDGWEVDPSIPSTSNWCPPREEEEPREKRQKIGEDSSFSDFDSLFDQLTENLSHNKSQENRSPAMRSLIENLRNNPRISSRQGSPITNASGLGYSAPGSILRRSRASAIPVLPNFHDDSADEEEEENSERSDTVMGFLAFDVKTSTTTPLILRNLNNNFKCHMRNRRLTVCCNENLIETYQLTKSNGKNEWEKIGQTRLPNLNSFPIDLHYRCGTAVGMSSRMEEVEQGQIFTDVFNFHRFHSPIQQDILTILHRDAPEHASRLFGKSPKLTQCHMISDDLLAVTMTFHKRRSSPLHIGATISILDSSITVYPNYHEYLKLLFTHHLPDLLPRHWTYLNPTPAHEQPWFKNSLINVSNPDELNNFDRLFEVYHILISNFNNVKSTSNPLTDAFFNAAEAEDFMNMGKSTNHYPRDTSAWNHFHENEEFGATLYYHPIDPVLFLKVGSFWLVAHRQADVSDDFIVSKNLEH
Protein: SIGNAL PEPTIDE PEPTIDASE-LIKE 2 (F4I3Q0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endosome membrane {ECO:0000256|ARBA:ARBA00004337}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004337}.
Interaction partners:
Sequence:
MDSLRFLRILLLSSSILLLSLRSTVTAGDIVHQDNLAPKKPGCENDFVLVKVQTWIDGVENEEFVGVGARFGKRIVSKEKNANQTHLVFANPRDSCTPLKNKLSGDVVIVERGNCRFTAKANNAEAAGASALLIINNQKELYKMVCEPDETDLDIQIPAVMLPQDAGASLQKMLANSSKVSAQLYSPRRPAVDVAEVFLWLMAIGTILCASYWSAWSAREAAIEHDKLLKDAIDEIPNTNDGGSGVVEINSISAIFFVVLASGFLVILYKLMSYWFVELLVVVFCIGGVEGLQTCLVALLSRWFQRAADTYVKVPFLGPISYLTLAVSPFCIVFAVLWAVYRVHSFAWIGQDVLGIALIITVLQIVHVPNLKVGTVLLSCAFLYDIFWVFVSKKLFHESVMIVVTRGDKSGEDGIPMLLKIPRMFDPWGGYSIIGFGDILLPGLLIAFALRYDWLANKTLRTGYFIWAMVAYGLGLLITYVALNLMDGHGQPALLYIVPFTLGTMLTLARKRDDLWILWTKGEPERACPHHVRLEQCSEK
Protein: IFT81 (Intraflagellar transport protein 81 homolog) (Q6IVW2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}.
Interaction partners:
Sequence:
MSEQLKFIVEQLNKEPFKKNFNLITFDSLEPMQLLQTLSDVLAEIDPKQAIDIREELPEQTAKRMFTLLGMLKYKPSGGMSEVSSFRQGLVSGSKPVVHPILHWLLQRIPELKKRAYLARFLVKLEVPAEFLQDDVIAETYHQYEELVEGFKNIHKECEQLKSSGFSTAEIRRDIVAMEEEKDQLIKRVERLRKRVEAVANHQRMLDLARQLRVEREREESLAHQKQEQKNQLFQAEQRLQRCQIQLKDLQQAAADEKPESLMKRLEEDIKFNSYMVSEKLPRELENMRKVVQYLQKVASEPAMGQAELRELEDKIRETNTEINHLIEKRMMRNDPMDDKLSLFRQQAAIIVRKKETKVEELQEAREELAAVERELNMKTSQAQERGGELIRGDEFKRYVAKMRGKSSTYKKKRQEIAELKAEYGVLQRTEEILRERHTAGQQQLQSLEAQRGISGYSDTQEELERVSAIKSELDEMKGRTLDDMSEMVKKLNSVIAEKKSALSPLIKDLRALRQEHAELAPEYEEKKAQYETCAAGLESNRSTLEQEVRTLREETAQEESRYHHINCEREIIESQIQRAAEQSKISQSMDVQVRRTALREKYIANTAEQESLGKVLRQQVKQVRENQEPNMRQMKMWKDLETLLECKKQCYLKAQSQAPIGHVIQDVGKDMLVL
Protein: Protein BUR2 (Bypass UAS requirement protein 2) (Chromosome stability protein 4) (Q05949)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the BUR kinase complex involved in transcription regulation. This complex phosphorylates 'Ser-120' of the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B, the localization of the PAF1 complex to the chromatin, and the silencing of telomeric-associated genes. Also required for histone H3 'Lys-4' trimethylation. May phosphorylate the 'Ser-5' of the RBP1 carboxy-terminal domain (CTD) repeats. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase. Also required for vegetative growth itself. The kinase activity of the complex requires the presence of BUR2. Overexpression of BUR2 interferes with mitotic chromosome segregation.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Serine/threonine-protein kinase BUR1
- CTD kinase subunit alpha
- CTD kinase subunit beta
- Transcription elongation factor SPT5
- DNA-directed RNA polymerase II subunit RPB1
- Transcription elongation factor SPT4
- Cell division control protein 73
- CTD kinase subunit gamma
- RNA polymerase-associated protein LEO1
- RNA polymerase-associated protein CTR9
Sequence:
MSATSSSGDVKKFQAVPKPTSNASPPPASSGFNARTLWPDLIETPENQWVFECKDIIEKIGTNGPIAVEIKKNMEKCLMYFYTLKKKLNLFDHTYTASCILFYRYWFIYGIPTAITECIHISQGILVTACKTMENNRPIEAYIKATCEFLMQNIPSLKSRTNIDKLKWEFRDKLVTNEKKILCLFGFDLNISNPKELIEEVFSGYYRFNRDHNLPENFKKAFPKILQESRNFMVQAVTQPVSLLCDGYTFIVLSLIYCGLEYKKLVDKDFRYPKNFFKDRFPIEVTPENFANIFTDYKLLEENFFNLKSNKGAKLQIDSSMIDSVIDESGDVENEVSEISDPFNYELIKSGEVKEEFLNHIETRVKDLLDKAKQESMKRKAKDPIRTPDAKKPKI