wanglab/gogpt-training-data huggingface dataset:
Protein: BcDNA.GH02220 (OXA1L mitochondrial inner membrane protein, isoform A) (OXA1L mitochondrial inner membrane protein, isoform B) (Q9Y171)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU003945}. Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
- Large ribosomal subunit protein mL45
- DSec61alpha
- Cytochrome c oxidase subunit 2
- Large ribosomal subunit protein mL49
- Large ribosomal subunit protein mL51
- Mitochondrial ribosomal protein L48, isoform A
- Large ribosomal subunit protein mL62
- ER membrane protein complex subunit 3
- GH07821p
- Large ribosomal subunit protein bL17m
Sequence:
MLAHRMQLWRTTNAAMAMTSAAGRFTPQASTGSRRDLYLQRITRGSSLPLAAPEKWSNLGQLRFASGGATAAGVSATKGEEFMQAVPKTELVDLPDIPAAPVPPPADGLNVMDVMNAAGEPSFASIGLGGWSPVGMVQNCLEFLHCTWDIPWWGTIAIGTLAVRTIIFPLVILAQRNSAKMNNNMPQMQMLQLKMTEARQSGNAIESARYAQEMMLFMREKGVNPLKNMVVPLAQAPLFISFFMGLRQMANAPVESMRDGGLFWFTDLTMADPFYLLPLITSATLYLTIEIGTDSARLSAANMNTMKYVLRALPIVIFPFTMNFPAAILTYWACSNFISLGQVAVLRIPSVREYFKIEKMLTHAPSALPPKKGFVGGMKESWDNMKISKEIEERQRLDEIRFAKAGKGPLVKTYKFDPTKVAKPISAEPHMRLKEPPNKQG
Protein: Paraneoplastic antigen Ma2 (40 kDa neuronal protein) (Onconeuronal antigen Ma2) (Paraneoplastic neuronal antigen MM2) (Q9UL42)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:10050892}.
Interaction partners:
- Amphiphysin
- Dihydropyrimidinase-related protein 5
- Leucine-rich glioma-inactivated protein 1
- Myc box-dependent-interacting protein 1
- Zinc finger protein ZIC 4
- Contactin-associated protein-like 2
- IgLON family member 5
- Inactive dipeptidyl peptidase 10
- A-type potassium channel modulatory protein DPP6
- Delta and Notch-like epidermal growth factor-related receptor
Sequence:
MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEERDGYGRWNHEGDD
Protein: Probable eukaryotic initiation factor 4A (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (O15919)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MRALRCVRRGVYRQSVRLCYFMSLECSLRPITGASARLLCRFTAPTWPRKNEVEEGDVGTTESTSQDVRSIFRSNIETHSEVSLESSASAALPPKTAALDVSVLDSKGNAVPVNPVKLFSDLDNLPDWLSKGLQSSGFSCTTPIQSYTIPVLDEGHDMIGLAPTGSGKTVAFAVPALKKFQWSPNGSPRIVVLAPTRELVQQTAKVFHQLSSGKVRVCERYGGAPREAQARRLHNGCDVLVACPGRLKDFLQNGDVIFDEVSFLVFDEADRLLDMGFKVQLDDILGYFSSHRPAQTMMWSATWPPVVEQLAQEYLSQNRYVIRSGTAGTGLQVNENIKQHIFFADAPEERVKTLVSLIKEGKIDENTAKMMIFVERQTDTENAAYALARMLGIHSRCIGVVHGGMQQRQRDHIMGIFKEGRIRILVATDVASRGLDFPDVTCVVNLIAPKNIDSYCHRIGRTGRAGRTGESFTFIGRSDGSLAKDLINYLEKCGMDVPQRLVEFAEEHAQGEEIKRMKRPWRGRQQREGRSQSRGGREPAPRDSGW
Protein: Metal transporter cnnm-1 (CNNM family homolog 1) (A3QM97)
Organism: Caenorhabditis elegans
Function: Probable metal transporter. Probably acts redundantly with the other metal transport proteins cnnm-2, cnnm-3, cnnm-4 and cnnm-5 to regulate Mg(2+) homeostasis. Promotes postembryonic gonad development by regulating Mg(2+) levels, probably via AMPK signaling.
Subcellular location: Basolateral cell membrane {ECO:0000269|PubMed:27564576}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Probable GMP synthase
Sequence:
MSASCLRLLTLSLFILGQCNVTAAQNGVDDEVTTVTAILDSATTAAADNSTVPTQSASNNNTSQSSKIPTIFGMRVELPADDPFGYDKHGVCSVTPEEEFKVVIYGNHLDKIHQIIWTFTNNCSEPAYVIDALNHFKVHFNHKATFHLTLKLLPEMVHAYKMCVKPKVAPGSPPLGEIYPLDDISTWLTTERPPKEYFLPLPLQIACIGFLLCLSALFSGLTLGLMSLTPQELELVIKSGAIKEQKCAAKILPVRKKGNLLLCSLLLGNVIVNSAISILMGELTTGIYALIGSTMGIVIFGEILPQSICVKKGLEVGAHTISITQLFIFLTFPIAWPVSKLLDCLLGDEYQAYDRKRLMELIKMSITDNGQVSNELKIAVGAMEIADKVVKDVMTKIEDVFMLPDTTVLNAKTVMEIVKMGYTRIPVYQYGDKNNVTDMLFVKDLALLDPDDNFTVKTVCGYHKHPVKFVMNDTPLPNLLEAFKKGEGHLAMVKRLINTDDKHDPSYVLVGVVTLEDIVEEILQAEINDEFDIVSDNVNKVKIKKEQNRDATKYFGDHEAPQTMISMQLQMVALQWLVSNERGFRQEFLDTNVLERLIRSSARRVDVSALMAMGDDAINVPRLAKVYTKDELSDKYILILEGRIQVTIGASGMMFEAGPWHHFGGEIMAKLVDGAATLGRSMSIVGTSELSARRPDLMFKPDYSAVVKEDCTYLEISVSAYINAYKASLMQRERPLNDLSDVSHNSSAHNSNLSLVEKPGPITDPSAMLVPENVRKPSVVSMDSPKILVGLGQHPVAPVAEEEEMALLDQP
Protein: Protein kinase MCK1 (EC 2.7.12.1) (Meiosis and centromere regulatory kinase) (P21965)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be an autophosphorylating tyrosine kinase, a bifunctional (serine/tyrosine-specific) protein kinase, or a serine kinase that is a substrate for an associated tyrosine kinase. MCK1 is a transcriptional activator of IME1, it stimulates spore maturation, and play a positive regulatory role in both mitotic centromere function and activation of early meiotic gene expression.
Interaction partners:
- Putative lipase ROG1
- N-alpha-acetyltransferase NAT5
- Cell division control protein 6
- Serine/threonine-protein kinase RIM11/MSD1
- G2/mitotic-specific cyclin-2
- M-phase inducer phosphatase
- Peroxisomal membrane protein PMP27
- H/ACA ribonucleoprotein complex subunit CBF5
- N-acetyltransferase ECO1
- S-phase entry cyclin-5
Sequence:
MSTEEQNGVPLQRGSEFIADDVTSNKSNNTRRMLVKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNELRNDDTFLPRGFTEPIKLPNLFDFNDFELQILGEFADKIKPTKVAE
Protein: Solute carrier family 13 (Sodium/sulphate symporters), member 1 (Solute carrier family 13 member 1) (Q6PE27)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Sulfate anion transporter 1
- Sodium-dependent phosphate transporter 1-A
- Solute carrier family 26 member 6,-like.
- Solute carrier family 26 member 2
- Solute carrier family 26 member 6
- Rh family, C glycoprotein,-like 1
- Solute carrier family 41 member 1
Sequence:
MRRLRCSWSALKPLIIISTPLAILPLPLVIKTKEAECAYVLILMAVYWMTEVLPLSVTALIPALLFPLFGIMKSSQVASQYFKDFHLLLLGVICLATSIEKWGLHRRIALRLVTGLGVNPGMLMLGFMVGCAFLSMWLSNTSTVAMVMPIVEAVIQQVLSASEEANKDHKGALNGISNPALQLEDIEAQHDQSEKIKSIEAGITEPEPTSEEHETAKAPTPPYSGKYRTREDHMMCKGLSLCIAYSSSIGGLTTLSGTSTNLIFAEYIYQYYPECTIVNFGNWFVLCLPICIIMLILSWLFLHWMYLGSNFRASLCSRQRTEKEKITARVLRDHYNSLGPISWQEIVTLIIFILMAILWFTRNPGFMPGWSSLFSDNPGYATDATVALLLGFLFFLLPSHKLNADHYEALITWKDFQACMPWEISLLVGGGFALAEGTKISGLSSWVAELLTPLGSLPPLATVTIACLIVTSITEVASNAATMTIFLPILAPLAEAIGVNPLYMLIPTALAVSFSFLLPVSNPPNAIVFTYGHLTSMDMVKAGLGVNVIGILTVLLALTTWGTPLLKLDTYPDWAPVVNSTGV
Protein: Fatty acyl-CoA reductase (EC 1.2.1.84) (Q9W0Y5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTVDLSPVQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIFQRIKDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLLGTRRALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAITPDLLKPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVSPAAYEPLPGWVDNLNGPTGLMIGCGKGVIRSVLVNQQNKAEVIPVDYAINGLIVIPYEFNKQAKRPTNVPVYNITNADHRKMTMGTVVEMSKRINKQFPFNAGLWYPDPCVTTNQLYHNFNVALFHWLPAYFLDFLMLILGQKRFMLRVQEKISTGLGVLQFFTLNAWCFRSDNYASLWNKLNEEDKAIFNMNMNTENTEEEYMIECAKGARKFILKEKEEDLPTARVHMKIQRVVDVVCKTVIVGLFFYYLLKWTGVLAIF
Protein: T. brucei spp.-specific protein (Q382J6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWTPRSDGCTTAERLRAARRRETAKLYENTYELRRRGYICDESGATNACHRRALENKEGNRSGCVTEEVADIRHQEPAADVMVSIDEGGSIKEGECQNVEGPQGLYTTGSFRRTSTVSVSTVEQPIKLLDAAWSRYDTQQVPRWSVSGRKADKHRKNRAPTLSRPSSGPFVRSHMGSASSSKRVGAAPSTALPARLNCFPHVPNPSEGTSVPPSTSATTVSLTPASGKVGRCFTPSRRRRQSCCQPRGSAEVQDRDRKRATGVVTLTGDEYMRVQQIISRV
Protein: Heterogeneous nuclear ribonucleoprotein U like 1 (M0QZV6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNC
Protein: Kininogen-1 [Cleaved into: Kininogen-1 heavy chain; Bradykinin; Kininogen-1 light chain] (O08677)
Organism: Mus musculus (Mouse)
Function: Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. LMW-kininogen inhibits the aggregation of thrombocytes. LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Subcellular location: Secreted, extracellular space.
Interaction partners:
- B2 bradykinin receptor
- B1 bradykinin receptor
- Plasma kallikrein
- Angiotensin-converting enzyme
- Protachykinin-1
- HMW kininogen-II
- Angiotensin-converting enzyme-like protein Ace3
- Thimet oligopeptidase
- Angiotensinogen
- Endothelin receptor type B
Sequence:
MKLITTLLLCSGLLLTLTQGEEAQEIDCNDEAVFQAVDFSLKQFNPGVKSGNQYMLHRVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLAWQDCDFKDAEEAATGECTATVGKRENEFFIVTQTCKIAPSKAPILKAYFPCIGCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERFPSLHGDCVALPNGDDGECRGNLFMDINNKIANFSQSCTLYSGDDLVEALPKPCPGCPRDIPVDSPELKEVLGHSIAQLNAENDHPFYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNTELAEDCEIKHLGQSLDCNANVYMRPWENKVVPTVKCQALDMTEMARRPPGFSPFRSVTVQETKEGRTVSPPYIAREQEERDAETEQGPTHGHGWLHEKQIKANKNHRGHKHGHDHGHWSPRRHGLGHGHQKPHGLGHGHQLKLDYLRHQREDGDDHTHTVGHGHGHGHGHGHGHGHGHGHGHGHGHGHGHGKHTNKDKNSVKQTTQRTESLASSSEYSTTSTQMQGRTEGPTLTPPRAQPTVTSSGFQDSDFIEDVVATTPPYDTGAHDDLIPDIHVQPDSLSFKLISDFPEATSPKCPGRPWKPASWEDPNTETTEFSDFDLLDALS
Protein: Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) (B4E9I9)
Organism: Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))
Function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
Interaction partners:
Sequence:
MDTLWDISPPVSPATPVWPGDTPVAVERVWRMEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAPIGAVPLDTYLGPCRVIHCIGAAPVVRPADVEAALDGVPPRVLLRTYARAAVEQWDSNFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAHRRVRAHRMAILEGIVLDDVPPGDYELIALPLKFATLDASPVRAVLRALPAQAS
Protein: RE03009p (Q8SZE8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLALLFAVPFAIAFRVEELTERFRENNETYNVTRPFCMNKNLSDDQLQSFRYTLVFVQYLVPFCVISFVYIQMAVRLWGTRAPGNAQDSRDITLLKNKKKVIKMLIIVVIILGLCWLPLQLYNILYVTIPEINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEKFKREFNKRFAACFCKFKTSMDAHERTFSMHTRASSIRSTYANSSMRIRSNLFGPARGGVNNGKPGLHMPRVHGSGANSGIYNGSSGQNNNVNGQHHQHQSVVTFAATPGVSAPGVGVAMPPWRRNNFKPLHPNVIECEDDVALMELPSTTPPSEELASGAGVQLALLSRESSSCICEQEFGSQTECDGTCILSEVSRVHLPGSQAKDKDAGKSLWQPL
Protein: Thiol methyltransferase 1A (F8VQX6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFSNLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAEC
Protein: Synaptobrevin homolog YKT6 (Q5AI79)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004342}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004342}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004342}.
Interaction partners:
- Golgi SNAP receptor complex member 1
- Sft1p
- V-SNARE protein
- t-SNARE syntaxin
- t-SNARE coiled-coil homology domain-containing protein
- SNAP receptor
- SNAP receptor
- Protein transport protein SEC22
- Vam7p
- Syntaxin-binding protein
Sequence:
MKIYYIGILRSSGDKALELTSARDLSQFSFFERNGVSQFMTFFAETVSQRTQPGQRQSVEEGNYIGHTYTRSEGISGIIITDKDYPVRPAYTLINKILEEYLSLHPKSDWENIDKANETLQYGQLEAYLKKYQDPTQADSIMKVQQELDDTKVVLHKTIEGVLQRGEKLDSLVDKSEALSSSSRMFYKQAKKTNSCCVIM
Protein: Homeobox protein Hox-C8 (Homeobox protein Hox-3A) (P31273)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-C9
- Homeobox protein Hox-C6
- Transmembrane anterior posterior transformation protein 1 homolog
- Pre-B-cell leukemia transcription factor 1
- Mothers against decapentaplegic homolog 6
- Homeobox and leucine zipper protein Homez
Sequence:
MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD
Protein: Vitamin D3 receptor A (VDR-A) (1,25-dihydroxyvitamin D3 receptor A) (Nuclear receptor subfamily 1 group I member 1-A) (Q9PTN2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P11473, ECO:0000255|PROSITE-ProRule:PRU00407}. Cytoplasm {ECO:0000250|UniProtKB:P11473}. Note=Localizes mainly to the nucleus. Translocated into the nucleus via both ligand-dependent and ligand-independent pathways; ligand-independent nuclear translocation is mediated by IPO4. {ECO:0000250|UniProtKB:P11473}.
Interaction partners:
Sequence:
MLTENSAVNSGGKSKCEAGACESRVNGDATSVMDLMAVSTSATGQDEFDRNAPRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGNCTITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKKDLIMKRKEEEAAREARKPRLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVREGPVTRSASRAASLHSLSDASSDSFNHSPESVDTKLNFSNLLMMYQDSGSPDSSEEDQQSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS
Protein: Hippocalcin-like protein 1 (Protein Rem-1) (P42324)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVEEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRGEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF
Protein: Glucan endo-1,3-beta-glucosidase, acidic isoform (EC 3.2.1.39) ((1->3)-beta-glucan endohydrolase) ((1->3)-beta-glucanase) (Beta-1,3-endoglucanase) (Beta-1,3-glucanase 2) (AtBG2) (Pathogenesis-related protein 2) (PR-2) (P33157)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Implicated in the defense of plants against pathogens (Probable). Not involved in plasmodesmal callose degradation and in the gating of plasmodesmata during tobamovirus infection.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:23656331}. Secreted, extracellular space, apoplast {ECO:0000269|PubMed:23656331}. Secreted, cell wall {ECO:0000269|PubMed:23656331}. Note=Exported in the apoplast and secreted to the cell wall under treatment with salicylic acid (SA). {ECO:0000269|PubMed:23656331}.
Interaction partners:
- Pathogenesis-related protein 5
- Pathogenesis-related protein 1
- CAP superfamily protein
- Pathogenesis-related protein 1
- Hevein-like preproprotein
- Basic endochitinase B
- Regulatory protein NPR1
- Defensin-like protein 16
- Aspartyl protease AED1
- Lipase-like PAD4
Sequence:
MSESRSLASPPMLMILLSLVIASFFNHTAGQIGVCYGMLGDTLPSPSDVVALYKQQNIQRMRLYGPDPGALAALRGSDIELILDVPSSDLERLASSQTEADKWVQENVQSYRDGVRFRYINVGNEVKPSVGGFLLQAMQNIENAVSGAGLEVKVSTAIATDTTTDTSPPSQGRFRDEYKSFLEPVIGFLASKQSPLLVNLYPYFSYMGDTANIHLDYALFTAQSTVDNDPGYSYQNLFDANLDSVYAALEKSGGGSLEIVVSETGWPTEGAVGTSVENAKTYVNNLIQHVKNGSPRRPGKAIETYIFAMFDENKKEPTYEKFWGLFHPDRQSKYEVNFN
Protein: Translocon-associated protein subunit alpha (Signal sequence receptor subunit alpha) (Q9W335)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
Interaction partners:
- Translocon-associated protein subunit gamma
- Translocon-associated protein subunit beta
- Translocon-associated protein subunit delta
- Derlin-1
- DSec61alpha
Sequence:
MRHLMFLMLMVLPIVICTFSAPNKFGAYAAEAVEDDLVDVEGEEGAVTGEDAEADEDSDTGSSSSPNADTYLLFTKPLYTPGQQLDLPGGKPVEFLIGFTNKGAEEFVIETVEASFRYPMDFNYFIQNFSAVAYNREVKPGFESTVSYTFLPSDQFAGRPFGLNIALAYRDANGIQYNEAVFNETVLISEVDEGLDGETFFLYVLLAGIVVLLLVIGQQYLLGSSGKRKRAAAKKVIETGTANDSTIDYDWVPQETLRALQKSPPKSKTPKTSPKPTKPASPKAASQQSPKQRKVKRSAGDD
Protein: Large ribosomal subunit protein eL24 (60S ribosomal protein L24) (Q8BP67)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:36517592}.
Interaction partners:
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS10
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL16
- Large ribosomal subunit protein uL24
- Elongation factor 2
- Small ribosomal subunit protein uS7
Sequence:
MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR
Protein: Protein-lysine palmitoyltransferase CyaC (EC 2.3.1.-) (Cyclolysin-activating lysine-acyltransferase CyaC) (P0A3I5)
Organism: Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Function: Protein-lysine palmitoyltransferase that catalyzes palmitoylation of the protoxin (CyaA) at two internal lysine residues, thereby converting it to the active toxin. Has strong preference for palmitoyl-CoA (hexadecanoyl-CoA) substrate, compared to other acyl-CoA substrates such as myristoyl-CoA (tetradecanoyl-CoA).
Subcellular location: Cytoplasm {ECO:0000305|PubMed:8973351}.
Interaction partners:
- Bifunctional hemolysin/adenylate cyclase
- Cyclolysin secretion/processing ATP-binding protein CyaB
- Protein CyaD
- Protein CyaE
Sequence:
MLPSAQAPSLLNPTDDFAALGNIAWLWMNSPMHRDWPVHLLARNTLAPIQLGQYILLRCNDVPVAYCSWALMDADTELSYVMAPSSLGGNAWNCGDRLWIIDWIAPFSRDDNRALRRALAERHPDSVGRSLRVRRGGDTARVKEYRGRALDAAAARAQLDRYHAELIAGLRASNGGYAPRGRGTA
Protein: Complement component C3-4 (Q9DDV9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
ANKYQALKDIKIPEGPDFFDEDYTGSQYVNLYAQFPSHKLEKVVLVSFQTGYIFIQMDKTIYTPESTVKYRVFTLNSGLEPVTDSINVEIMNPDGITLLQEDFKPDDGMTSRVFPVPEITRVFLCYSIILTHLSGKLLPVNSSALILFLYSFGNWKVVAKFKNSPHKNFTADFEVKEYVLPSFEVKLTVSKSFFYVDDDELTVNINARYLFEEPVKGVCFVVFGVIQGVDRTSFPSSLQRVELKEGVGKAVLKRQHINKTFTDINMLLHKSLYISVNVLTDTGSEMVKAEKKGIFIVKSPYSIHFKKTPPYFKPGMPYDVSVYVTNPDDSPAKDIDVEVLQKDQRVLGKTHDNGIAKITINTRAGDSELPITVTTKVDGLGDDRQGTQNMTAKPYQTKDNSQNYIHIHIHSTDVKIKDQLTVDLSLGSSPAAQNDNHEITFLILSKGQLINSQKIEWNKGQGLMSLPLMVNKDMIPSFRVVAYYHVGQNEVVSDSVWIDVKDTCMGLVRMLPYCAEPHRLVVTLCSSHIYHSPPESGVQPVSTLSTVIPMCLSPPLKNGSLLCYYFSVEVLHSGLLKHDLRLCVPYCRLKVKDVRHSGSYAPQKRVTLSIIGDPGAKVGLVAVDKGVYVLNDKSRLTQTKIWDMIEKHDTGCTAGSGMDSMGVFYDAGLVFAFNTAKGTPQRTVSSCPVNSRRRRAVTVNDVGTTLASQYTGLERQCCMDGMRNNILDYTCERRSQYISDGTECVGAFLKCCREMVTKGEEAKIDQLTLARSEEEDDRFESLDEIKSRSFFPESWLWKEENLPQCLKDEECVIQKSIDLPDSITSWQITVIGLSKTHGICVSEPLTLIVRKNFFLDLKLPYSAVRNEQLEIKAILHNYIDDTITVRVELRETSDVCSSASKKGKYVVTVMVDPMSTRSVPFVIIPMKLGLHTIEVKASVRDWGGQDGVKKELRVVAEGVRTKLQVKNVELDPARHGGTDIVHVGSGALTDQVPNTLASTHISVTGQQLARTIEAAISGSPLGDLLQQPSGCGEQNMMKMTLPLIATLYLDETKQWDKVGLERRKEAVNFIKMGYEQEMAYRKADGSYATFLYERSGTWLTAYVVKVFAMANPFIVISKDVLCSAIKWLVMERQRPNGIFEESGKILTPSMMGDVLGKDLNNTLTAFVLIAMQEAHTFCTNYDGLSELPDSMKKAMQYLESQNQYLTNPYSVAMTSYALANKGKLNKDILFKYSSTDRTHWPAPGKNLFTLEATAYALLALVKAGAYEEAGPIVRWLNRLGFKGGEESYTQATIMVFQAVAEYKMKAGKVKDIDLNVDIDITGRAQVIKWSFNKRNALLTRSDKVMLHENFTVTAKGTGQGGLLVTTLYYAMPKEKNQDCKNFVLDVELIKQDTVSLKEATETYKLYIDVLFNSDRNATMTILDISLLTGFVVDFEDLKQLSTGREKYIQKFEMDQTLSERGSLIIYLDQVSFKLPDKVAFRIHKVQDVGLLQPVGVTVYEYYAQENRCVKFYHPLKKDGTLNRLCQDDVCRCAEESCSYQKKLGDVSEIKLLDKACESHMDYVFKASMVNATLESYTDTYLMEIKMIIKEGTDLVLEGGKRLFLAHPSCREALDLKEGQSYLLIGDTADLIQSVTDRYVLGERTWIEYWPTSDECNMQDQEKTRKRCLEIYDFVHEMQSEGCVN
Protein: Transcription factor (A0A1D8PNL1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Carbon catabolite-derepressing protein kinase
- Hgt7p
Sequence:
MSMSTPMPTPTSLDTKKMPPKEKKNKDDRPYKCTFCDKAFHRLEHQTRHIRTHTGEKPHACTFPGCVKRFSRSDELTRHLRIHTNPSSRKRKNKNQNMMINPNATTATTTGPAGMAIPTSNLPPGSYAIPNTAIPFSIDRNGNHVYHQPYPVYFVPHANGYMQPMVQTQGVTVVPNTDQQQQQYYQQQQQQYQFQERPQHQQQQQTNIGTNNHLQQNGSAVFSLPSSPTMASAQTPNSGTSSSSESIKLAPLSIPNNISRSQQQQQQQQQQQIPKSESSTSLYSDGNKLFSRPNSTLHSLGSSPENNNASGPLSGVPTPSFSNLNDYFQQKSNSNNSRLFNASSSSLSSLSGKIRSSSSTNLAGLQRLTPLTSTTNNTNNTTTSNTTNNNMTKPSIIPKQPSSTSLNLEFYNGNNQQQQNYHTHKKSRPNSPSQTPIHLSSSRKSANNSFIISPNETPLQTPLQSPQLKPYQDQPPTNVNINVSAPSDTFIGTAVTEKLNNISSIAGNGTQLPPIRSVLSFTSLVDYPDPKQKNVAPPVVDTTNVARGETNGSNGNNSNAKPMSLTNLLS
Protein: Aldo-keto reductase family 1, member C12 (Q91X42)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSSKQHYVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKREDLFVTTKLWCGCFRPELVKPALEKSLKSLQLDYVDLYLIHYPVPMKPGDNESPLDENGKFLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQSKLLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKRNKRSPALIALRYLFQRGIVPLAQSFKENEMRENLQVFEFQLSPEDMKTLDGLNKNFRYLPAEFLADHPEYPFSEEY
Protein: Isocitrate lyase (ICL) (EC 4.1.3.1) (Isocitrase) (Isocitratase) (O50078)
Organism: Hyphomicrobium methylovorum
Function: Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. May be involved in the assimilation of one-carbon compounds via the isocitrate lyase-positive serine pathway.
Interaction partners:
Sequence:
MAHKKTYSQLRSELLARYPVGLTKGGVSIDDIVQLRLQSPYESHLDVARAMASVMRADMAAYDRDTGKFTQSLGCWSGFHAQQMIKAVKRLRGTTKGAYVYLSGWMVAGLRNRWGHLPDQSMHEKTSVVDLIEEIYVSLRQADEVALNDLFNELKDARAKGATNKACEEIISRIDGFESHVVPIIADIDAGFGNEHATYLLAKEMIKAGACCLQIENQVSDAKQCGHQDGKVTVPREDFIEKLRACRLAFEELGVDDGVIVARTDSLGASLTQKIPVSQQAGDFASSYIKWLKTEPITDANPLSEGELAIWQSGNFARPIRMPNGLFSFREGTGRARVIEDCIASLKDGDADLIWIETDTPNVDEIASMVAEIRKQVPDAKLVYNNSPSFNWTLNLRKQVRAQWISEGKIAEADYPDGTALMSAQYDTSELGREADDRLRQFQVDISARAGVFHNLITLPTFHLTAKSTDELSHGYFGEDRMLAYVATVQREEIRRSISAVRHQHEVGSDLGDTFKEMVSGDRALKAGGAHNTMNQFAAE
Protein: U6 snRNA-associated Sm-like protein LSm4 (D4A2C6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU365049}.
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm8
- U6 snRNA-associated Sm-like protein LSm7
- U6 snRNA-associated Sm-like protein LSm3
- U6 snRNA-associated Sm-like protein LSm1
- Small nuclear ribonucleoprotein Sm D3
- U6 snRNA-associated Sm-like protein LSm6
- U6 snRNA-associated Sm-like protein LSm5
- U4/U6 small nuclear ribonucleoprotein Prp31
- Protein PAT1 homolog 1
- Small nuclear ribonucleoprotein-associated protein N
Sequence:
MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECYIRGSTIKYLRIPDEIIDMVREEAAKGRGRGGPQQQKQQKGRGMGGAGRGVFGGRGRGGIPGAGRGQPEKKPGRQAGKQ