wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein PYUK71.03c (Q9UT00)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}; Single-pass membrane protein {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized protein C691.05c
- Oxysterol-binding protein homolog C23B6.01c
- Vesicle-associated membrane protein-associated protein scs2
- Vesicle-associated membrane protein-associated protein scs22
Sequence:
MSSQAEPSKGASNADPNEKVEKMHLPTDTAGGGVKVKVKEQEASPSDKNNLNPQSAGVSEVQVQDDTGARGSGARDLKVPKQMQAPKSSEEKSDVDGVPTRPVSERELRKRDAMQFIQRHQKVRNILAQYCPWLTDERLQLCIELKILFMQHFQDSRLVLYTAVMSFLFGYLRFGFLSLFIIMAVCIQYYRICDRRVKVNFKDDYTRYLSTRKLENDSETVTWLNTFLQQFWYIFEPSLSERITEITDQILSENVPSFIDSMALSEFTLGTKSPRMGFIRSYPKTEEDTVMMDLRLAFSPNDISDLTGREIAACIKPKIALDLKIGKSIASAKMPVLIEDLSFTGNLRVKVKLIDKYPYAKTVGLTFTEKPVFSYILKPLGGDKFGFDIGNIPGLTTFITEQIHNTLGPMMYSPNVYELDIESMMGAAGLNTALGAVEFKLRKGDGFKDGLGGAVDPYVVIKNSADRVIGKSKVAHNTGSPVFNETFYSVLNSFSENLNLEVYDFNDIRSDKLLGSAVLPLATLEAMPVTNDAFVELTLKGKTVGRLNYDMKFHAVVPDSGEEITKVDGPGVLQFTVHQCKELSNDPSKRPTAYAKLIINNKEVYTTRKIKKNNNPSWEESFGTLLPEGKNATLGVQIFTEESEHPFGTANVSLQDLFAATKTGLLWFPLQHAPSGRVRMSVMWKPAQLNNDSISSMALATPIGAIRIHLRSANNLHSKIPGKKCDSYARIMSHNTKQFRTVVIASNVNPFWDEYMYAPVITKHDIFFLQVMNYNSSGEDKLIGQTPINISNFINQGENGALMEYHDPRELTVPLSSTRGIKGNATITFKCDFFPSAVTTSLSPDVTPAPKASSTVATDKVNIEVLPESQKTPTAVDNTSTSRGSTSVKTSKPKKISELLMPSEAVNAALDFESGFMGFDIISYKIAKPAQELAIFLDDLPHHIFLSSALNVTGGATLHEYGNTFIRQLEYSQCTFKLLDGDKEVGSKTMLSRDLISKGATKPLEIAFPDGASILVAFRLTPVPVKLEEVEMYENMGEMTVDVIKATDLPAADSNGKSDPFVVFELQGEEVYRTKTHKRTLNPTFNESFEVELPCKQTCNFVANVFDWDFGNKDDHLGSCVIDCKLLQQQQQTNYEIPLDSKQGVLYLRITLSPKWVLRSKRAGNSSLVEGILGQTASIVGMPLKGISTVGNVAVDGVASVANLTNKMRKGISRGFKGIHHEKAK
Protein: Cbb3-type cytochrome c oxidase subunit II (Cytochrome c oxidase, cbb3-type, subunit O) (Cytochrome-c oxidase, cbb3-type subunit II) (D9IA44)
Organism: Stutzerimonas stutzeri (Pseudomonas stutzeri)
Interaction partners:
Sequence:
MKSHEKLEKNVGLLTLFMILAVSIGGLTQIVPLFFQDSVNEPVEGMKPYTALQLEGRDLYIREGCVGCHSQMIRPFRAETERYGHYSVAGESVYDHPFLWGSKRTGPDLARVGGRYSDDWHRAHLYNPRNVVPESKMPSYPWLVENTLDGKDTAKKMSALRMLGVPYTEEDIAGARDSVNGKTEMDAMVAYLQVLGTALTNKR
Protein: Probable sodium/metabolite cotransporter BASS5, chloroplastic (Bile acid transporter 5) (Bile acid-sodium symporter family protein 5) (F4JPW1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plastidic transporter involved in the biosynthesis of aliphatic glucosinolates by translocating the biosynthetic intermediates of Met-derived glucosinolates across chloroplast membranes. Transports short chain (C2) alpha-keto acids, such as 4-methylsulfanyl-2-oxobutanoic acid, from the cytosol to the chloroplast where they are subjected to chain elongation cycles. Functions also in the transport of chain-elongated (C3 to C8) Met derivatives from the chloroplast to the cytosol. Does not seem to be involved in the transport of indole-derived glucosinolates.
Subcellular location: Membrane {ECO:0000305|PubMed:19542295}; Multi-pass membrane protein {ECO:0000305|PubMed:19542295}. Plastid, chloroplast envelope {ECO:0000305|PubMed:19542295}.
Interaction partners:
- Methionine aminotransferase BCAT4
- 3-isopropylmalate dehydratase small subunit 3
- Cytochrome P450 83A1
- 3-isopropylmalate dehydrogenase 1, chloroplastic
- Methylthioalkylmalate synthase 1, chloroplastic
- 3-isopropylmalate dehydratase small subunit 2
- Cytosolic sulfotransferase 18
- Cytosolic sulfotransferase 17
- Transcription factor MYB28
- Transcription factor MYB29
Sequence:
MGVISPTETLFLKSQHRLLQPRNYSYALAFHSTRRVANFPRNSFSSLGSCSVDFPLRSNPISQNSKSIHPWRRYVSESDSNELYHKKVSSIMETLKQAYSFIPHGILLSTILALVYPPSFTWFKPRYFVPGLGFMMFAVGINSNERDFLEALKRPDAIFAGYIGQYLIKPLLGYIFGVIAVSLFNLPTSIGAGIMLVSCVSGAQLSNYTTFLTDPSLAALSIVMTSISTATAVLVTPMLSLLLIGKKLPVDVFGMISSILQVVITPIAAGLLLNRLFPRLSNAIKPFLPALTVIDMSCCIGAPLALNIDSILSPFGATILFLVITFHLLAFVAGYFFTGFFFSKAPDVKALQRTISYETGMQSSLLALALATKFFQDPLVGVPPAISTVVMSLMGVSLVTIWKNRKE
Protein: Replication protein A subunit (A0A0G2KAT3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus, PML body {ECO:0000256|ARBA:ARBA00004322}.
Interaction partners:
Sequence:
MVGHLSEGAIAVRRHSGNIRPITTGNSPPRYRLLMSDGLNTLSSFMLATQLNALVEGGQLASNCVCQVHRFIVNTLKDGRRVVILMDLEVVKSAGEVGVKIGNPVPYNEGHAQQQAVSAPASAATPPASKPQPQNGSLGVGSTVAKAYGASKPFGKPAGTGLLQPTSGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSIELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGTLKIANKQFSAVKNDYEMTFNNETSVLPCEDGHHLPTVQFDFTGIGDLESKSKDSLVDIIGICKSYEDATKITVKSNNREVAKRNICLMDMSGKVVTATLWGEDADKFDGSRQPVMAIKGARVSDFGGRSLSVLSSSTVLVNPDIPEAYKLRGWFDSEGQALDGVSISDLRSGGTGGSNTNWKTLYEAKSENLGQGDKADYFSTVATVVFLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDREFPNFKYRMILSVNIADFQENQWVTCFQESAEAILGQNTVYLGELKEKNEQAFEEVFQNANFRSFTFRIRVKLETYNDESRIKATVIDVKPVDYRDYSKRLIMNIRKNI
Protein: ACP53C14C (Q6GUV2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKSKQVFYIAFSLLLLGSLLPNDVESLRVDLNKLAECTESGLKVATTLLVRAIPCVKKLAKCADFRAIKTKDLDITALALLGYQYLQTVVNNQRCLLISLKEGYDAVSPHLDKLISGKCLPGLS
Protein: Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 (PI(4)P 5-kinase-like protein 1) (PtdIns(4)P-5-kinase-like protein 1) (EC 2.7.1.68) (Q5T9C9)
Organism: Homo sapiens (Human)
Function: May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3.
Subcellular location: Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures. {ECO:0000250}.
Interaction partners:
- Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
- Phosphatidylinositol 4-kinase beta
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- Phosphatidylinositol 4-kinase alpha
- Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
- Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
- Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4-kinase type 2-alpha
Sequence:
MAAPSPGPREVLAPSPEAGCRAVTSSRRGLLWRLRDKQSRLGLFEISPGHELHGMTCMMQAGLWAATQVSMDHPPTGPPSRDDFSEVLTQVHEGFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKTINLGPQRSWFLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRYPGRTFSTVSPARYARRLCQWVEAHTE
Protein: Tautomerase/MIF superfamily protein (F4K9G5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- AT5g64160/MHJ24_14
- At2g42060
Sequence:
MPCLNLSTNVNLDGVDTSSILSEASSTVAKIIGKPENYVMIVLKGSVPMSFGGTEDPAAYGELVSIGGLNADVNKKLSAAVSAILETKLSVPKSRFFLKFYDTKDHQSQEYAQCLHALHQHY
Protein: EspH (Q7DB74)
Organism: Escherichia coli O157:H7
Interaction partners:
- T3SS structure protein SepQ
- T3SS secreted effector EspZ
- T3SS secreted effector EspG
- EspF
Sequence:
MSLSGAVFKTFLTSEHASWNRFNRRLHIPNEDIVDEIQLKARMQQRHHRVYPEIGDSTIVSFRGKDYAVHFIKDGPKDDYVYKVQRITPENGCFSTLFSVFSGGVTKALERKLNERHITPLSSTWFPRTPLEGILAERGLSSLLRRVQSTERLDNRAIATRASSYSVL
Protein: Chondroitin sulfate ABC exolyase (EC 4.2.2.21) (Chondroitin ABC exoeliminase) (Chondroitin ABC lyase II) (Chondroitin sulfate ABC lyase II) (ChS ABC lyase II) (Chondroitinase ABC II) (cABC II) (Exochondroitinase ABC) (C5G6D7)
Organism: Bacteroides thetaiotaomicron
Function: Broad-specificity glycosaminoglycan lyase, which acts in an exolytic fashion degrading chondroitin sulfates and dermatan sulfate to yield only disaccharide products. Has a preference for chondroitin 4-sulfate over chondroitin 6-sulfate. Has extremely low activity against hyaluronic acid. Is not active against acharan sulfate, heparin or heparan sulfate.
Subcellular location: Periplasm {ECO:0000250|UniProtKB:Q8A2I1}.
Interaction partners:
Sequence:
MLILSFLCPAFLNAQIVTDERMFSFEEPQLPACITGVQSQLGISGAHYKDGKHSLEWTFEPNGRLELRKDLKFEKKDPTGKDLYLSAFIVWIYNEQPQDAAIEFEFLKDGRKCASFPFGINFKGWRAAWVCYERDMQGTPEEGMNELRIVAPDAKGRLFIDHLITATKVDARQQTADLQVPFVNAGTTNHWLVLYKHSLLKPDIELTPVSDKQRQEMKLLEKRFRDMIYTKGKVTEKEAETIRKKYDLYQITYKDGQVSGVPVFMVRASEAYERMIPDWDKDMLTKMGIEMRAYFDLMKRIAVAYNNSEAGSPIRKEMRRKFLAMYDHITDQGVAYGSCWGNIHHYGYSVRGLYPAYFLMKDVLREEGKLLEAERTLRWYAITNEVYPKPEGNGIDMDSFNTQTTGRIASILMMEDTPEKLQYLKSFSRWIDYGCRPAPGLAGSFKVDGGAFHHRNNYPAYAVGGLDGATNMIYLFSRTSLAVSELAHRTVKDVLLAMRFYCNKLNFPLSMSGRHPDGKGKLVPMHYAIMAIAGTPDGKGDFDKEMASAYLRLVSSDSSSAEQAPEYMPKVSNAQERKIAKRLVENGFRAEPDPQGNLSLGYGCVSVQRRENWSAVARGHSRYLWAAEHYLGHNLYGRYLAHGSLQILTAPPGQTVTPTTSGWQQEGFDWNRIPGVTSIHLPLDLLKANVLNVDTFSGMEEMLYSDEAFAGGLSQGKMNGNFGMKLHEHDKYNGTHRARKSFHFIDGMIVCLGSDIENTNMDYPTETTIFQLAVTDKAAHDYWKNNAGEGKVWMDHLGTGYYVPVAARFEKNFPQYSRMQDTGKETKGDWVSLIIDHGKAPKAGSYEYAILPGTDRKTMTAFAKKPAYSVLQQDRNAHILESPSDRITSYVLFETPQSLLPGGLLQRTDTSCLVMVRKESADKVLLTVAQPDLALYRGPSDEAFDKDGKRMERSIYSRPWIDNESGEIPVTVTLKGRWKVVETPYCKVVSEDKKQTVLRFLCKDGASYEVELEK
Protein: Kazrin, periplakin interacting protein (A0A1B0GWK2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MESTLATSNSATGPVTFSHVFGQQCQLMQAAVQSLHTLNDQISHFIVTKSKALEEDKDPFLPTEKETLKSSMILMRHLLMDAQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRQSLSLSEGEEQMDRLQQVELVRTTPMSHWKAGTVQAWLEVVMAMPMYVKACTENVKSGKVLLSLSDEDLQLGLGVCSSLHRRKLRLAIEDYRDAEAGRSLSKAAELDHHWVAKAWLNDIGLSQYSQAFQNHLVDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREALQERRARCETQNIDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAMATALGIPSGKHILRRHLAEEMSAVFHPANSTGIREAERFGTPPGRASSVTRAGKEENSSGLKYKAGRLPLGKIGRGFSSKDPDFHDDYGSLQNEDCGDDDPQSRLEQCRLEGYNSLEVTNV
Protein: Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial (EC 1.1.1.41) (IDH-VI) (Isocitric dehydrogenase 6) (NAD(+)-specific ICDH 6) (Q8LG77)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalytic subunit of the NAD(+)-dependent isocitrate dehydrogenase involved in the oxidative decarboxylation of isocitrate to 2-oxoglutarate (Probable). Performs an essential role in the oxidative function of the citric acid cycle.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14671022}.
Interaction partners:
- Cytosolic isocitrate dehydrogenase
- Peroxisomal isocitrate dehydrogenase
- 2-oxoglutarate dehydrogenase, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Aconitate hydratase 3, mitochondrial
- Isocitrate dehydrogenase regulatory subunit 2, mitochondrial
- Isocitrate dehydrogenase regulatory subunit 1, mitochondrial
- Isocitrate dehydrogenase, chloroplastic/mitochondrial
- Putative isocitrate dehydrogenase subunit-like 4
- Aconitate hydratase 2, mitochondrial
Sequence:
MTMTAFLARRLIGNGSSQILGTSSSSSGPFISVSRAFFSSSTPIKATLFPGDGIGPEIAESVKQVFTAADVVIDWDEQFVGTEVDPRTNSFLTWDNLQSVLKNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVDLITIRENTEGEYSGLEHQVVKGVVESLKIITRKASMRVAEYAFLYAKTHGRKKVSAIHKANIMQKTDGLFLQCCDEVAAKYPEIYYEKVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLVGGLGLTPSMNIGEDGIALAEAVHGSAPDIAGMNLANPTALLLSGVMMLRHLKLNKQAEQIHSAIINTIAEGKYRTADLGGSSTTTDFTKAICDHL
Protein: Paraxanthine methyltransferase 2 (EC 2.1.1.-) (SABATH methyltransferase PXMT2) (Q9C9M2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
- Signal transducer, putative
- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
- Embryonic abundant protein-like
- At5g27290
- Calcium-binding site protein
- Protein-lysine N-methyltransferase At1g66680
- AT4g21620/F17L22_80
- Uncharacterized protein F28B23.5
- At1g33030
Sequence:
MTTTQDWIMIGGYGPESYNQQSSYQRALLEAAKDKMTEAISANLDLDLISNRFIVADFGCASGPNTFVAVQNIIDAVEEKYLRETGQNPEDNIEFQVLFNDLRINDFNTLFQTLPPGRRYFSAGVPGSFFNRVLPKQSFHIAVMSYAFLFTSKIPKGIMDRDSPLWNKDMQCTGFNPAVKKAYLEQYSIDTKNLLDARAEELMPGGLMLLLGSCMRDGVKMSETLKGTVMDFIGESLNDLAQKGVTEQEKVDTFKTSIYFAEQGEIRQIIEENGKFTIEAFEDIIHSKNEFPLDPKTLAISFKALYGAFISAHFGIEVMRKAFELVEVKAREQISRLHKVKPGMQYLIVLRKN
Protein: Calcium-dependent protein kinase 14 (EC 2.7.11.1) (P93759)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Protein RALF-like 4
Sequence:
MGNCCGTAGSLIQDKQKKGFKLPNPFSNEYGNHHDGLKLIVLKEPTGHEIKQKYKLGRELGRGEFGVTYLCTEIETGEIFACKSILKKKLKTSIDIEDVKREVEIMRQMPEHPNIVTLKETYEDDKAVHLVMELCEGGELFDRIVARGHYTERAAASVIKTIIEVVQMCHKHGVMHRDLKPENFLFANKKETASLKAIDFGLSVFFKPGERFNEIVGSPYYMAPEVLRRSYGQEIDIWSAGVILYILLCGVPPFWAETEHGVAKAILKSVIDFKRDPWPKVSDNAKDLIKKMLHPDPRRRLTAQQVLDHPWIQNGKNASNVSLGETVRARLKQFSVMNKLKKRALRVIAEHLSVEETSCIKERFQVMDTSNRGKITITELGIGLQKLGIVVPQDDIQILMDAGDVDKDGYLDVNEFVAISVHIRKLGNDEHLKKAFTFFDKNKSGYIEIEELRDALADDVDTTSEEVVEAIILDVDTNKDGKISYDEFATMMKTGTDWRKASRQYSRDLFKCLSLKLMQDGSLQSNGDTK
Protein: WD repeat-containing protein VIP3 (Protein BOUQUET-1) (boq-1) (Protein SKI8 homolog) (Protein VERNALIZATION INDEPENDENCE 3) (Protein ZWERGERL) (zwg) (Q9SZQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the flowering repressor and MADS box gene FLC. Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) and histone dimethylation on 'Lys-36' (H3K36me2) at the FLC locus. Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus. Not required for meiotic recombination or progression. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). Required for proper progression of cell differentiation process.
Subcellular location: Nucleus {ECO:0000269|PubMed:20363855, ECO:0000269|PubMed:21571540, ECO:0000269|PubMed:22511887}. Cytoplasm {ECO:0000269|PubMed:22511887}.
Interaction partners:
- Tetratricopeptide repeat protein SKI3
- DExH-box ATP-dependent RNA helicase DExH11
- Protein LEO1 homolog
- Protein CTR9 homolog
- Protein PAF1 homolog
- Protein RTF1 homolog
- Protein CDC73 homolog
- FACT complex subunit SSRP1
- Transducin/WD40 repeat-like superfamily protein
- FACT complex subunit SPT16
Sequence:
MKLAGLKSIENAHEDSVWAATWVPATEDRPALLLTGSLDETVKLWRPDELDLVRTNTGHSLGVAALAAHPSGIIAASSSIDSFVRVFDVDTNATIAVLEAPPSEVWGMQFEPKGTILAVAGGSSASVKLWDTASWRLISTLSIPRPDAPKPSDKTSSKKFVLSVAWSPNGKRLACGSMDGTICVFDVDRSKLLHQLEGHNMPVRSLVFSPVDPRVLFSGSDDGHVNMHDAEGKTLLGSMSGHTSWVLSVDASPDGGAIATGSSDRTVRLWDLKMRAAIQTMSNHNDQVWSVAFRPPGGTGVRAGRLASVSDDKSVSLYDYS
Protein: tRNA(adenine(34)) deaminase, chloroplastic (TADA) (EC 3.5.4.33) (tRNA adenosine deaminase arginine) (tRNA arginine adenosine deaminase) (Q9S7I0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Deaminates adenosines to inosines in tRNA-Arg(ACG). Exclusively involved in A-to-I editing of the prokaryote-type chloroplast-tRNA and not involved in C-to-U editing.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:19460869, ECO:0000269|PubMed:19602623}.
Interaction partners:
- tRNA-specific adenosine deaminase TAD3
- N6-mAMP deaminase
- Cytidine deaminase 2
- Cytidine deaminase 5
- Cytidine deaminase 3
- Cytidine deaminase 7
- Cytidine deaminase 6
- Cytidine deaminase 8
- Cytidine deaminase 1
- AT4g39900/T5J17_70
Sequence:
MFNTYTNSLQWPIRSRNQQDYCSLLPERSESYKLSKAYTSSRCYCVSSRSSCCCCCSTPSSSSFVKPKVLINPGFVLYGVRQSTLIQWPSFQRRLLVGGGRLMGCEVYSSCDGIRRKNRSFKLRCLEESDECCGGRSCSDDVEAMISFLSEELIDEERKWNLVSRVKEKKKVGNVRKVSVEGSNSYGNGRVSQRVKKPEGFGRRKEIKEDVKLNERYDCEHCGRRKKSSELESESRRGSKLVTGEYIGKSYRGDEEREVRPRRRKSSSCSSYYSLASSGEFESDTEDQEEDVEIYRENVRSSEKKVVDQSAKRLKSRKEASQMHSRKKRDESSTGVDSRYQKQIFEEGENSNQAVTLNQRRRKKFSQTENRVSESTGNYEEDMEIHEVHVNDAETSSQNQKLFNEREDYRVHSIRNDSGNENIESSQHQLKERLETRYSSEDRVSEMRRRTKYSSSQEEGINVLQNFPEVTNNQQPLVEERISKQAGTRRTTEHISESSEIHDIDIRNTYVSQREDQIRNQEVHAGLVSGLQSERKQQDYHIEHNPLQTTQSDRTSVSVSHTSDAVRYTEIQRKSEKRLIGQGSTTAVQSDSKVEKNGAQKEDSRLDHANSKKDGQTTLGLQSYQSKLSEEASSSQSSLMASRTKLQLVDLVSEEMQGSETTLIPPSSQLVSRRSGQSYRTGGVSIQEISHGTSESGYTTAFEHPRAGASVNSQSAGELMGFTSHEDAMGSAHRLEQASEKYVGEFVKKAKHGVINPETEEQRAESNQLKRRDSRRSSGGSGAKGPSDEMWVTDSAQGTPHPGATEGNAAVGNAIFKRNGRSLWNVIADIARLRWGSRAGSPDSSAKPAGRSSPNESVSSATWFSGREHDGSSDDNTKGDKVLPQEAPSLHQVEVGQTSPRSQSEYPGTTKLKQRSERHEGVVSSPSSTILEGGSVSNRMSSTSGNQIVGVDEEEGGNFEFRLPETALTEVPMKLPSRNLIRSPPIKESSESSLTEASSDQNFTVGEGRRYPRMDAGQNPLLFPGRNLRSPAVMEPPVPRPRMVSGSSSLREQVEQQQPLSAKSQEETGSVSADSALIQRKLQRNKQVVRDSFEEWEEAYKVEAERRTVDEIFMREALVEAKKAADTWEVPVGAVLVHDGKIIARGYNLVEELRDSTAHAEMICIREGSKALRSWRLADTTLYVTLEPCPMCAGAILQARVNTLVWGAPNKLLGADGSWIRLFPGGEGNGSEASEKPPPPVHPFHPKMTIRRGVLESECAQTMQQFFQLRRKKKDKNSDPPTPTDHHHHHLPKLLNKMHQVLPFFCL
Protein: Disintegrin and metalloproteinase domain-containing protein 10 homolog (ADAM 10 homolog) (EC 3.4.24.81) (G5EFD9)
Organism: Caenorhabditis elegans
Function: Metalloprotease (By similarity). Acts together with protease adm-4 and in a cell autonomous manner to facilitate lin-12/Notch signaling during developmental cell fate decision, including anchor cell/ventral uterine precursor cell decision and vulva precursor cell specification. By modulating glp-1/Notch signaling, plays a role in germline development. Probably by modulating BMP-like Sma/Mab signaling via the shedding of unc-40 ectodomain, involved in the regulation of body size and mesoderm development. Probably by shedding ephrin efn-4, regulates axon guidance of SDQL neuron during development.
Subcellular location: Cell membrane {ECO:0000269|PubMed:28068334}; Single-pass type I membrane protein {ECO:0000305}. Basolateral cell membrane {ECO:0000269|PubMed:28068334}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:28068334}; Single-pass type I membrane protein {ECO:0000305}. Note=Localizes to the basolateral cell membrane in embryos. {ECO:0000269|PubMed:28068334}.
Interaction partners:
- Protein lin-12
- Tetraspanin-12
- Tetraspanin-14
- Nicastrin
- Presenilin sel-12
- Presenilin hop-1
- Gamma-secretase subunit pen-2
- RRM domain-containing protein
Sequence:
MSSPIRNRLQLVVTLIFCLFFENVNGLNNFIDNFETLNYRATHVANQVTRRKRSIDSAASHYQEPIGFRFNAYNRTFHVQLHPIDDSLFHEDHMSDVDGGYADIKPSHFLYEGYLKDDPNSHVHGSVFDGVFEGHIQTGEGRRYSIDKAAKYFERDDRPTQYHSIIYRDDEINHRKWRVKRDAENLSEQMQGCGFSSRVRREMTDVQNSGESTDFFTNYMTMGGRSKRANTLRDHDGLYFVRTCSLYMQADHKLYEHIRMKEGNNDPIRTREEIVSLFYNHIKAVNEIYEGTNFNGIKGLHFVIQRTSIYTPDSCDRGRAKTDSDNPFCEENVDVSNFLNLNSQRNHSAFCLAYALTFRDFVGGTLGLAWVASPQFNTAGGICQVHQRYNEGSRGWVYRSLNTGIVTLVNYGNRVPARVSQLTLAHEIGHNFGSPHDFPAECQPGLPDGNFIMFASATSGDKPNNGKFSPCSVKNISAVLAVVLKSMPVDPTRNASPVGIGKRNCFQERTSAFCGNQIYEPGEECDCGFSQADCDQMGDKCCVPHEARGNGGPGPCKRKPGAQCSPSQGYCCNPDTCSLHGKNEEKICRQESECSNLQTCDGRNAQCPVSPPKHDGIPCQDSTKVCSSGQCNGSVCAMFGLEDCFLTEGKADELCFLACIKDGKCTSSVHLPEFSANRTNFLQNMRKDKPGLILHPGSPCNNYKGYCDIFRKCRSVDANGPLARLKNLLFNKRTIETLTQWAQDNWWVVGVGGLVFLVIMALFVKCCAVHTPSTNPNKPPALNIYQTLTRPGTLIRQHRQRHRAAAGSVPPGPGAQPRSGAASAPSRTTPSARPSAPPLVAPQVAVAVPPGVVGPPIPLIATHPGSSSSTPAVIVLEPPPPYTAADPGSAMGGPRRGHRKNKRQTSSDAAGSSGNGGKKKGK
Protein: Probable conserved lipoprotein LpqU (P96378)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable conserved transmembrane protein
- Fluoride-specific ion channel FluC 1
- Probable conserved membrane protein
- Uncharacterized protein Rv3630
- Possible lipoprotein LpqQ
- Possible conserved transmembrane protein
- Possible conserved membrane protein
- Exopolyphosphatase 2
- Conserved protein
- Probable transport accessory protein MmpS1
Sequence:
MSPRRWLRAVAVIGATAMLLASSCTWQLSLFITDGVPPPPGDPVPPVDTHAGGRPADQLREWAEKRAAALGIPVIALEAYAYAARVAEVENPKCHLAWTTLAGIGRVESHHGTYRGATIAPNGDVSPPIRGVRLDGTGGTLRIVDRDGGGLDGDAAVERAMGPMQFISETWRLYGVAARNDGIANVDNIDDAALSAAGYLCWRGKDLATPRGWITALRAYNNSVIYARAVRDWATAYAAGHPL
Protein: Vacuolar protein sorting-associated protein VTA1 (VPS20-associated protein 1) (Q06263)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a role in the formation of the multivesicular body (MVB). Required for the sorting of lipids to form intralumenal vesicles and for fluid-phase transport to the vacuole. Required for sorting the plasma membrane proteins STE2 and STE3 into the MVB. Acts a cofactor of VSP4, promotes the oligomerization of VPS4 and stimulates its ATPase activity by 6- to 8-fold.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14701806}. Endosome membrane {ECO:0000269|PubMed:14562095}; Peripheral membrane protein {ECO:0000269|PubMed:14701806}.
Interaction partners:
- Vacuolar protein sorting-associated protein IST1
- Vacuolar protein-sorting-associated protein 46
- Vacuolar protein sorting-associated protein 4
- Vacuolar protein-sorting-associated protein 60
- VPS4-associated protein 1
- Vacuolar-sorting protein SNF7
- DOA4-independent degradation protein 4
- Vacuolar protein-sorting-associated protein 24
- GTP cyclohydrolase 1
- Vacuolar protein sorting-associated protein 20
Sequence:
MASNAARVVATAKDFDKVGLGIIGYYLQLYAVELILSEEDRSQEMTALATELLDTIEAFKKEIGGESEAEDSDKSLHVMNTLIHDQEKAKIYMLNFTMSLYNEKLKQLKDGPWDVMLKRSLWCCIDLFSCILHLWKENISETSTNSLQKRIKYCKIYLSKLAKGEIGSSDEKTLDYADFADDSEEIKDEDVDHQTSDLENNNNDKVEGLAPKDQTTSYEPVDEVPEFIDDADSVNEEEQTVDKNEDAITKDEQQVVKKEVDLTRPSAPSEPAAAEHKSYTKDELTKIMDRASKIEQIQKLAKYAISALNYEDLPTAKDELTKALDLLNSI
Protein: mRNA export factor ICP27 homolog (Mta) (ORF57 protein homolog) (Protein EB2) (Protein SM) (Q04360)
Organism: Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Function: Promotes the nuclear export of a subset of early and late viral mRNAs by interacting with mRNAs and cellular export proteins. Additionally may prevent the establishment of cellular antiviral state, by acting as an alternative splicing factor for cellular RNAs such as STAT1, resulting in a STAT1 mRNA incapable of producing the STAT1alpha isoform.
Subcellular location: Host nucleus {ECO:0000269|PubMed:10846090}. Host cytoplasm {ECO:0000269|PubMed:10846090}. Note=shuttles between the nucleus and the cytoplasm.
Interaction partners:
Sequence:
MVPSQRLSRTSSISSNEDPAESHILELEAVSDTNTDCDLDPMEGSEEHSTDGEISSSEEEDEDPTPAHAIPARPSSVVITPTSASFVIPRKKWDLQDKTVTLHRSPLCRDEDEKEETGNSSYTRGHKRRRGEVHGCTDESYGKRRHLPPGARAPRAPRAPRVPRAPRSPRAPRSNRATRGPRSESRGAGRSTRKQARQERSQRPLPNKPWFDMSLVKPVSKITFVTLPSPLASLTLEPIQDPFLQSMLAVAAHPEIGAWQKVQPRHELRRSYKTLREFFTKSTNKDTWLDARMQAIQNAGLCTLVAMLEETIFWLQEITYHGDLPLAPAEDILLACAMSLSKVILTKLKELAPCFLPNTRDYNFVKQLFYITCATARQNKVVETLSSSYVKQPLCLLAAYAAVAPAYINANCRRRHDEVEFLGHYIKNYNPGTLSSLLTEAVETHTRDCRSASCSRLVRAILSPGTGSLGLFFVPGLNQ
Protein: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Q2I824)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MAGNNFVIEVEKGKDASDGQPSIGPVYRSSFAANGFPAPIPGMESCWDIFRMSVEKYPDNRMLGRRQIVDGKAGKYVWQTYREVYDIVIKVGNSIRSCDVVEGGKCGIYGANCPEWIISMEACNAHGLYCVPLYDTLGAGAVEFIICHAEISIAFVEEKKINELFKTFPASTEHLKTIVSFGKVTPEQKAEAEKHGLKIYPWEEFLQLGENKNYGLPVKKKTDICTIMYTSGTTGDPKGVFISNDSIVTLIAGVKRLLGSVNEQLTMKDVYISYLPLAHIFDRVIEELFISHGASIGFWRGDVKLLVEDIGELKPSIFCAVPRVLDRIYSGLLQKISAGGLLKKKMFDLAYTYKYYNMKKGRKHGEASPICDKIVFSKVKQGLGGNVRLILSGAAPLSTHVEEFLRVVACCHVLQGYGLTESCAGSFVSLPNELSMLGTVGPPVPNIDVRLESVPEMNYDALASTPRGEICIKGNTLFSGYYKREDLTREVLIDGWFHTGDIGEWQPNGSMKIIDRKKNIFKLSQGEYVAVENLENIYGLVSAIDSIWIYGNSFESFLVAVVNPNKEALESWAADNNVSGDFESLCKNPKAKEFILGELAKTGKEKKLKGFEIIKAVHLDPMPFDMERDLLTPTYKKKRPQLLKYYQSVIDEMYKSANKPNA
Protein: cAMP-regulated phosphoprotein 19-A (ARPP-19-A) (Q6DEB4)
Organism: Xenopus laevis (African clawed frog)
Function: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with ppp2r2d (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MSGENQETKAQEESSALEQKEIDDKVVSPEKSEEIKLKARYPNLGPKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAASDKTEVTGDHIPTPQDLPQRKPSLVASKLAG