wanglab/gogpt-training-data huggingface dataset:
Protein: Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP) (Q02650)
Organism: Mus musculus (Mouse)
Function: Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage. Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineage-specific genes. In turn, regulates cell adhesion and migration, induces V(H)-to-D(H)J(H) recombination, facilitates pre-B-cell receptor signaling and promotes development to the mature B-cell stage. Repression of the cohesin-release factor WAPL causes global changes of the chromosomal architecture in pro-B cells to facilitate the generation of a diverse antibody repertoire (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q02548}.
Interaction partners:
- Protein C-ets-1
- Interferon regulatory factor 4
- Transcription factor COE1
- DNA-binding protein Ikaros
- PR domain zinc finger protein 1
- B-cell antigen receptor complex-associated protein alpha chain
- Runt-related transcription factor 1
- PAX-interacting protein 1
- B-lymphocyte antigen CD19
- Transcription factor PU.1
Sequence:
MDLEKNYPTPRTIRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLTSPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSPAARGAAPPAAATAYDRH
Protein: At4g12320 (Cytochrome P450, family 706, subfamily A, polypeptide 6) (Q66GJ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- NAD
- NAD
- UDP-glycosyltransferase 91B1
- Aldo-keto reductase family 4 member C11
- NAD
- Aldo-keto reductase family 4 member C10
Sequence:
MSPISNLFAGNTINLTPYAILILIAIFSILWYLFKRSPQPHLPPGPRGLPIVGNLPFLDPDLHTYFTKLAESYGPIFKLNLGSKLTVVVNTPSLAREILKDQDINFSNHDVPLTARAVTYGGLDLVWLPYGAEWRMLRKVCVLKLLSHRTLNSFYELRRKEIRERTRYLYQKGQEESPVNVGEQVFLTMMNLTMNMLWGGSVKAEEMESVGTEFKEVISEITRLLGEPNVSDFFPRLARFDLQGLVKKMHVCARELDAILDRAIEQMQLLRTRDGDDGECKDFLQHLMKLKDQEADSEVPITVNHVKAVLVDLVVGGTDTSTNTIEFAMAELIRKPELMKRAQQELDEVVGKDNIIEESHITRLPFISAIMKETLRLYPTIPLLVPHRPSETALVGGYTIPKNTKIFINVWSIQRDPNVWEYPTEFRPERFLDKKSCDFTGTDYSYLPFGSGRRICAGIALAERMILYTLATLLHSFDWKIPEGHILDLKEKFGIVLKLKSPLVALPVPRLSNSNLYL
Protein: Gamma-aminobutyric acid receptor subunit rho-1 (GABA(A) receptor subunit rho-1) (GABAAR subunit rho-1) (GABA(C) receptor) (P56475)
Organism: Mus musculus (Mouse)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission (By similarity).
Subcellular location: Postsynaptic cell membrane {ECO:0000305|PubMed:16945976}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P24046}. Cell membrane {ECO:0000269|PubMed:25422464}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P24046}. Note=Located at the plasma membrane of astrocytes (PubMed:25422464). Located in the plasma membrane of glial cell processes (PubMed:25422464). {ECO:0000269|PubMed:25422464}.
Interaction partners:
- GABA
- Gamma-aminobutyric acid receptor subunit rho-2
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid receptor subunit alpha-5
- Gamma-aminobutyric acid receptor subunit alpha-2
- Gamma-aminobutyric acid receptor subunit epsilon
- Gamma-aminobutyric acid receptor subunit gamma-3
- Gamma-aminobutyric acid receptor subunit alpha-4
- Gamma-aminobutyric acid receptor subunit alpha-3
Sequence:
MLAVQNMKFGIFLLWWGWVLAAESTAHWPGREVHEPSRKGSRPQRQRRGAHDDAHKQGSPILRRSSDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSSNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKISCTCGLPQPRGVMLDSSYSDGEVNDLGGYMPENGEKPDRMMVQLTLASERGSPQRKGQRGSYVSMRINTHAIDKYSRIIFPAAYILFNLIYWSIFS
Protein: Alpha-amylase B (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) (P81641)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- 1,4-alpha-glucan branching enzyme
- Glycogen phosphorylase
- Glycogen debranching enzyme
- Alpha-amylase-related protein
- alpha-glucosidase
- Maltase A1
- Maltase A3
- Maltase A2
- alpha-glucosidase
- alpha-glucosidase
Sequence:
MFLAKSIVCLALLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAVKDSRPWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMAADGGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAISNYNDANEVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKVFRGKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQGPPTTDGHNIASPIFNSDNSCSGGWVCEHRWRQIYNMVAFRNTVGSDEIQNWWDNGSNQISFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRASIYIGSSEDDGVLAIHVNAKL
Protein: Aldo-keto reductase family 1 member D1 (H0ZPZ0)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Interaction partners:
- 3-oxo-5-alpha-steroid 4-dehydrogenase
- 3-oxo-5-alpha-steroid 4-dehydrogenase
- 11-beta-hydroxysteroid dehydrogenase type 2
- 11-beta-hydroxysteroid dehydrogenase 1
- Hydroxysteroid 17-beta dehydrogenase 2
- Polyprenal reductase
- Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Aromatase
- Cytochrome P450 family 8 subfamily B member 1
- Steroid 17-alpha-hydroxylase/17,20 lyase
Sequence:
MNLTAESHRIPLSDGNSIPLLGLGTYADPQKTPKGSCLEAVKIAIDAGYRHIDGAFVYFNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKPGDALYPKDENGKFIYHETDLCATWEALEACKDAGLAKSIGVSNFNRRQLEMIMNKPGLKYKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDESWVNVSSPPLLKDPLLNAIGKKYNKTAAQIALRFNVQRGVVVIPKSFNPQRIRENFQIFDFSLTENEMKEIEALNKNVRYVELLMWRDHPEYPFSDEF
Protein: Signal transducer and activator of transcription (K7EIF9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
Sequence:
MSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRLGDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGGSSATYMDQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLSPPAGLFTSARGSLS
Protein: Mesencephalic astrocyte-derived neurotrophic factor (Arginine-rich protein) (Protein ARMET) (P0C5H9)
Organism: Rattus norvegicus (Rat)
Function: Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain (By similarity). Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death (By similarity). Retained in the ER/sarcoplasmic reticulum (SR) through association with the endoplasmic reticulum chaperone protein HSPA5 under normal conditions (By similarity). Up-regulated and secreted by the ER/SR in response to ER stress and hypoxia (By similarity). Following secretion by the ER/SR, directly binds to 3-O-sulfogalactosylceramide, a lipid sulfatide in the outer cell membrane of target cells (By similarity). Sulfatide binding promotes its cellular uptake by endocytosis, and is required for its role in alleviating ER stress and cell toxicity under hypoxic and ER stress conditions (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P55145}. Endoplasmic reticulum lumen {ECO:0000250|UniProtKB:P55145}. Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:P55145}. Note=Retained in the endoplasmic reticulum (ER), and sarcoplasmic reticulum (SR) under normal conditions. Up-regulated and secreted by the ER/SR in response to ER stress and hypoxia. {ECO:0000250|UniProtKB:P55145}.
Interaction partners:
- Endoplasmic reticulum chaperone BiP
- Protein disulfide isomerase Creld2
- DnaJ homolog subfamily B member 11
- X-box-binding protein 1
- Stromal cell-derived factor 2-like 1
- Proactivator polypeptide-like 1
- Endoplasmin
- Calreticulin
Sequence:
MWATRGLAVALALSVLPDSRALRPGDCEVCISYLGRFYQDLKDRDVTFSPATIEEELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGEMCKGCAEKSDYIRKINELMPKYAPKAASARTDL
Protein: Uncharacterized protein (Q381S1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFQRLDEEVPNIGQLSDGGGSPKSLNGAEAARTHDRESFGAASDKSANLESYHPEPTDVPSAFADSAGVEGASEKDNASSESGCPEPLAAPPPCAAGAKDAFRYSKTTVPTHLDESGCTTPEPVLSSFFTDTDAIPTWEGMTLEQLNGLRDKMLSLLSGVSEAIRREEVKSPLSLGPSNELTDEEKQVVDASLQRLLVEAFEYSSLSDIKEMYLFAKAMQGKEASRMGAALQSIHRLTSRGNILISYKELQDFLRSSNRFTADWRDEFVSSIKRVLAAFLSMSHQPDVLNCFYPQLLVIARHEIFYTVLLRAAQGKSVLPQSLYHLSPEWLAATHSCKCTLQQLSQSLSNGTSVANMSLTRNSQCSTGYATNPARRPYIDSSMRWNPPRVRPRVPLGASPRMASCDSSVDRNQYHTEYEGRWETPTRPRRTFDMGVRRQMSTRSTSALLSSLGGKSSGAMSNTAMTVTTGRKTPLTRTRSNTAGMLTRTMSAVRHMDSCTTNYAAGIKIGSKPAAESPLKLQRTATQRPSGALTSVKPGTKIGQVFPSTVRVETRSRARDSYLVTPRK
Protein: Ras-related protein Rab-5A (EC 3.6.5.2) (Small GTP-binding protein rab5) (M0RC99)
Organism: Rattus norvegicus (Rat)
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P20339}; Lipid-anchor {ECO:0000250|UniProtKB:P20339}; Cytoplasmic side {ECO:0000250|UniProtKB:P18066}. Early endosome membrane {ECO:0000250|UniProtKB:P20339}; Lipid-anchor {ECO:0000250|UniProtKB:P20339}. Melanosome {ECO:0000250|UniProtKB:P20339}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P20339}. Cell projection, ruffle {ECO:0000250|UniProtKB:P18066}. Membrane {ECO:0000250|UniProtKB:P20339}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P20339}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:Q9CQD1}. Endosome membrane {ECO:0000250|UniProtKB:P20339}. Note=Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms. {ECO:0000250|UniProtKB:P20339}.
Interaction partners:
- Early endosome antigen 1
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Rabenosyn, RAB effector
- Ras and Rab interactor 1
- small monomeric GTPase
- Vacuolar protein sorting-associated protein 45
- Rab5 GDP/GTP exchange factor
- GTPase-activating protein and VPS9 domain-containing protein 1
- Rab GDP dissociation inhibitor alpha
- DCC-interacting protein 13-alpha
Sequence:
MANRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTPMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDLTEPAQPARSQCCSN
Protein: Prefoldin subunit 1 (Q9CWM4)
Organism: Mus musculus (Mouse)
Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
Interaction partners:
- Prefoldin subunit 2
- Prefoldin subunit 3
- Prefoldin subunit 4
- Prefoldin subunit 5
- Prefoldin subunit 6
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit gamma
- T-complex protein 1 subunit delta
- Programmed cell death protein 5
- T-complex protein 1 subunit beta
Sequence:
MAASVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEVIHNQLLEKQKIAKEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ
Protein: O-acetyltransferase WecH (EC 2.3.1.-) (P37669)
Organism: Escherichia coli (strain K12)
Function: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units. Catalyzes the acetylation of both cyclic ECA (ECA(CYC)) and phosphoglyceride-linked ECA (ECA(PG)).
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01949, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01949}.
Interaction partners:
- Inner membrane protein YiaA
- Inner membrane protein YiaB
- Glucans biosynthesis protein C
- Protein AroM
- Uncharacterized protein YpfG
- Alkaline phosphatase isozyme conversion protein
- Stationary phase-inducible protein CsiE
Sequence:
MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIANVLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIGLCLIFYSAIALLYIALFTSINMELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMAVIGIIANPNTVPQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFIISRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLGIYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQRIDRNRLVS
Protein: Calmodulin-binding receptor kinase CaMRLK (EC 2.7.11.1) (Calmodulin-binding receptor-like kinase) (AtCaMRLK) (Protein MATERNAL EFFECT EMBRYO ARREST 62) (Q9FK63)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Can phosphorylate the myelin basic protein in vitro. Required for endosperm development in embryos. Maybe involved in auxin and osmotic stress responses.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Putative pentatricopeptide repeat-containing protein At5g40405
- Glucan endo-1,3-beta-glucosidase 9
- Probable mitochondrial adenine nucleotide transporter BTL1
- Receptor-like kinase
- CDPK-related kinase 7
Sequence:
MFLKLFLLLSLVSFSHSDSSSTVSCPNGTDFHQLTTVFRYVSGFNSSWFSSNCSAVITHVVLPSRKLNGTVSWNPIRNLTRLRVLDLSNNSLDGSLPTWLWSMPGLVSVNLSRNRFGGSIRVIPVNGSVLSAVKELNLSFNRFKHAVNFTGFTNLTTLDLSHNSLGVLPLGLGSLSGLRHLDISRCKINGSVKPISGLKSLDYLDLSENSMNGSFPVDFPNLNHLQFLNLSANRFSGSVGFDKYRKFGKSAFLHGGDFVFNDSKIPYHHRIHRLPHRHPPPVRQRNVKTHRTNHTPLVIGLSSSLGALIIVIFAAAIILIRRRMKSARTKSRWAISNPTPLDFKMEKSGPFEFGTESGSSWVADIKEPTAAPVVMASKPLMNLTFKDLIVATSHFGTESVISDGTCGPLYRAVLPGDLHVAIKVLERIRDVDQNDAVTAFEALTRLKHPNLLTLSGYCIAGKEKLILYEFMANGDLHRWLHELPAGETNVEDWSADTWESHVGDSSPEKTNWLIRHRIAIGVARGLAYLHHVGTTHGHLVATNILLTETLEPRISDFGINNIARTGDDTNKNNVEFDVYSFGVILFELLTGKQGSDENVKSVRRLVKERRGEEALDSRLRLAAGESVNEMVESLRIGYFCTAETPVKRPTMQQVLGLLKDIRTVSR
Protein: Complement C3d receptor 2 (D3Z9F7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MGALGSLWVFFALIAPGVLGQCKLLPKYSFAKPTVVSDKSEFAVGTTWKYKCLPGYFRKSFTITCLESSKWSDAQQFCKRKPCMNPQEPLHGSVHINTGITFGSTITYSCNKGYRLIGDSSATCIISDNTVMWDNSVPICELIPCESPPAISNGYFQSSSRDSFFYGMVATYYCHVGKNREKLFDLVGEKSIYCTSKDNQVGIWNSPPPQCIARVKCPMPEIENGDVESGFKPSFFLNDTVMFKCKSGFIMKGSSIVWCQPDSKWSPPLPTCFRGCLPPQNILHGDYNEKDKEFFSVGQKVSYSCEPGYTLIGTNLVECTPLGAWSPSVPTCEVKSCDAIPNQLLNGRVLLPHNLQLGAEVSFVCDLGFQLKGKSSSQCVPEGETVIWNNKFPVCEQLSCDPPPEVNNTRRLYYSLPVLPGTVVRYTCLPGYRLIGEKAIFCISKDQVTATWDKATPICEPWNKMSACSKPIVPGGIINPGSRPPFKHGDSVTVTCKANFTMKGSKTVWCRANKMWGPTPLPVCESDFPLECPSLPTIHNGHHTGQHVEKFVAGLSVTYSCEPGYLLVGKKTIKCLSSGAWDDVIPTCKEAKCERPEKLPNGQVKEPPSLRVGTTVYFSCNEGYELQGQPSSKCVIVEQKAVWTKKPVCKEILCPPPPPVLNGRHSGRFSGNVPYGNNVTYMCDPSPEKGVNFTLIGEKTIYCTNSSEKTGIWSGPAPYCKLSISEAQCLRPQINRGQILSILKESYSYNDTVAFSCEPGFTLKGSGRIRCSAQGTWKPPVPVCEKGCQAPPKIINGQKEDRYFLNFDPGTSIRYSCDPGYFLVGEDTIHCTSEGKWTPIPPQCKVAECKPVGPHVFERPQNHFIRPAINSSCDEGFQISESAYQLCQGTIPWFIEIRLCKEITCPPPPIILNGTHTWRSSEDVPYGTVITYMCYPGSEEGVKFKLIGEQTIHCTSDSRGRGSWSSPAPLCKLSLPAVQCTEVHVENGVKLTDNKAPYFYNNSVTFKCRDGYILIGSSQIRCKANNTWDPEAPHCKKEGCEPMRKLPGISDHSLIKLVNRTCQNGYQLTGYTYEKCQNAENGTWFQKIAVCTVILCPPPPTIANGSHTGMMAEHFLYGNEVSYECDKGFYLLGEKSLQCKGHGSWSGPPPQCLQSSPLTHCPDPEVKYGYKLNKTHSAYSHNDIIHVVCNQGFIMNGSHLIRCHTNNTWLPGVPTCIRTASLGCQSPPTIPNGNHTGGTIARFSPGMSVMYSCYQGYLMAGEARLICTHEGTWSHPAPYCKEVNCSFPEDTNGIQKGFQPGKTYRFGTTVTLECEDGYSLEGSPQSQCQDENQWNPPLAICKNRSTVPLVSGISAGSAFIILISVIFFIILKSRERNYYTKTRPKDGALHLETREVYAVDPYNPAS
Protein: ATP synthase gamma chain 1, chloroplastic (F-ATPase gamma subunit 1) (Q01908)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- ATP synthase subunit beta, chloroplastic
- ATP synthase subunit d, mitochondrial
- ATP synthase subunit b, chloroplastic
- ATP synthase subunit delta, chloroplastic
- ATP synthase subunit alpha, chloroplastic
- ATP synthase epsilon chain, chloroplastic
- Photosystem II 22 kDa protein, chloroplastic
- ATP synthase subunit alpha
- ATP synthase subunit beta-2, mitochondrial
- ATP synthase subunit beta-3, mitochondrial
Sequence:
MACSNLTTMWVSSKPSLSADSSSLSFRSVLKCPTNTSSPPSRASSVSPLQASLRELRDRIDSVKNTQKITEAMKLVAAAKVRRAQEAVVNGRPFSETLVEVLYNINEQLQTDDVDVPLTKVRPVKKVALVVVTGDRGLCGGFNNFIIKKAEARIKELKGLGLEYTVISVGKKGNSYFLRRPYIPVDKYLEAGTLPTAKEAQAVADDVFSLFISEEVDKVELLYTKFVSLVKSEPVIHTLLPLSPKGEICDINGTCVDAAEDEFFRLTTKEGKLTVERETFRTPTADFSPILQFEQDPVQILDALLPLYLNSQILRALQESLASELAARMSAMSSASDNASDLKKSLSMVYNRKRQAKITGEILEIVAGANAQV
Protein: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) (Q09545)
Organism: Caenorhabditis elegans
Function: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
Interaction partners:
- Putative succinate dehydrogenase cytochrome b small subunit, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit
- Probable fumarate hydratase, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Probable NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- Probable NADH dehydrogenase flavoprotein 2, mitochondrial
Sequence:
MLARSARLLHSAELAANAIRAASGAPATAAAAEASFPSTDDVAAKTKKTGNRIKTFEIYRFNPEAPGAKPTVQKFDVDLDQCGTMILDALIKIKNEVDPTLTFRRSCREGICGSCAMNIGGQNTLACICKIDSDTSKSTKIYPLPHMFVVKDLVPDMNLFYAQYASIQPWIQKKTPLTLGEKQMHQSVAERDRLDGLYECILCACCSTSCPSYWWNADKYLGPAVLMQAYRWVIDSRDDYATERLHRMHDSFSAFKCHTIMNCTKTCPKHLNPAKAIGEIKSLLTGFTSKPAAEPSAF
Protein: Uracil phosphoribosyltransferase homolog (A0A0A0MRR5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGEFSMRQ
Protein: Two-component response regulator-like APRR1 (ABI3-interacting protein 1) (Pseudo-response regulator 1) (Timing of CAB expression 1) (Q9LKL2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Controls photoperiodic flowering response. Component of the circadian clock. Expression of several members of the ARR-like family is controlled by circadian rhythm. The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock. Positive regulator of CCA1 and LHY expression.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357, ECO:0000269|PubMed:18562312}.
Interaction partners:
- Adagio protein 1
- Protein GIGANTEA
- Transcription factor TCP21
- Protein LHY
- Protein EARLY FLOWERING 3
- Protein CCA1
- Protein EARLY FLOWERING 4
- Adagio protein 3
- Transcription factor LUX
- Transcription factor PIF3
Sequence:
MDLNGECKGGDGFIDRSRVRILLCDNDSTSLGEVFTLLSECSYQVTAVKSARQVIDALNAEGPDIDIILAEIDLPMAKGMKMLRYITRDKDLRRIPVIMMSRQDEVPVVVKCLKLGAADYLVKPLRTNELLNLWTHMWRRRRMLGLAEKNMLSYDFDLVGSDQSDPNTNSTNLFSDDTDDRSLRSTNPQRGNLSHQENEWSVATAPVHARDGGLGADGTATSSLAVTAIEPPLDHLAGSHHEPMKRNSNPAQFSSAPKKSRLKIGESSAFFTYVKSTVLRTNGQDPPLVDGNGSLHLHRGLAEKFQVVASEGINNTKQARRATPKSTVLRTNGQDPPLVNGNGSHHLHRGAAEKFQVVASEGINNTKQAHRSRGTEQYHSQGETLQNGASYPHSLERSRTLPTSMESHGRNYQEGNMNIPQVAMNRSKDSSQVDGSGFSAPNAYPYYMHGVMNQVMMQSAAMMPQYGHQIPHCQPNHPNGMTGYPYYHHPMNTSLQHSQMSLQNGQMSMVHHSWSPAGNPPSNEVRVNKLDRREEALLKFRRKRNQRCFDKKIRYVNRKRLAERRPRVKGQFVRKMNGVNVDLNGQPDSADYDDEEEEEEEEEEENRDSSPQDDALGT
Protein: Ferric uptake regulation protein (Ferric uptake regulator) (Q9ZM26)
Organism: Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MRRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVLETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIEHRQNEVVKKYQAKLISHDMKMFVWCKECQESDD
Protein: RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity) (O43251)
Organism: Homo sapiens (Human)
Function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.
Subcellular location: Nucleus. Cytoplasm {ECO:0000250}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein H
- KH domain-containing RNA-binding protein QKI
- RNA-binding protein with multiple splicing
- Heterogeneous nuclear ribonucleoprotein F
- Ataxin-1
- U1 small nuclear ribonucleoprotein C
- Pumilio homolog 1
- ELAV-like protein 1
- Heterogeneous nuclear ribonucleoprotein H2
- Epithelial splicing regulatory protein 2
Sequence:
MQNEPLTPGYHGFPARDSQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNDAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPATATAATAAAAAAAAYSDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY
Protein: Cytochrome P450 1A (EC 1.14.14.1) (Q1JQ70)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}. Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU368045}; Peripheral membrane protein {ECO:0000256|RuleBase:RU368045}. Microsome membrane {ECO:0000256|RuleBase:RU368045}; Peripheral membrane protein {ECO:0000256|RuleBase:RU368045}.
Interaction partners:
Sequence:
MMDVLLALRDLLQLSTRSVLLSLMVCLMLMFRRRQLVPGPFSWPVIGNAAQLGNTPHFYFSRMAQKYGDVFQIKLGSRNVVVLNGDAIKEALVKKATDFAGRPDFASFRFVSNGKSMAFGNYTPWWKLLRKVAQSTVRNFSTANIQTKQTFEKHIVSEIGELIRLFLNKSREQQFFQPHRYLVVSVANTMSAVCFGNRYAYDDAEFQQVVGRNDQFTKTVGAGSMVDVMPWMQYFPNPIRTLFDQFKELNKEFCAFIELKVSEHRKTISPSHVRDMTDAFIVALDKGLSGGSGVSLDKEFVPPTISDIFGASQDTLSTALQWIILLLVRYPEIQNRLQEDVGRVVDRSRLPTIADQPHLPYLMAFIYEVMRFTSFTPLTIPHSTTKDTSINGYPIPKDTVIFVNQWSLNHAPAKWDQPEVFNPQRFLDEDGSLNKDLTTNVLIFSLGKRRCIGEDVSKIQLFLFTSVLVHQCSFKAESTPNMDYEYGLTLKPKPFKVSVTARDSSDLLDSLVGTSQTPTEKRLKCN