wanglab/gogpt-training-data huggingface dataset:
Protein: Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) (Q9Y570)
Organism: Homo sapiens (Human)
Function: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.
Interaction partners:
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Leucine carboxyl methyltransferase 1
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
- Serine/threonine-protein phosphatase 2A activator
Sequence:
MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC
Protein: tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) (A2RUC4)
Organism: Homo sapiens (Human)
Function: tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.
Interaction partners:
- tRNA wybutosine-synthesizing protein 4
- tRNA wybutosine-synthesizing protein 2 homolog
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1
- tRNA wybutosine-synthesizing protein 3 homolog
- Ribosomal oxygenase 2
- Ribosomal oxygenase 1
Sequence:
MAGQHLPVPRLEGVSREQFMQHLYPQRKPLVLEGIDLGPCTSKWTVDYLSQVGGKKEVKIHVAAVAQMDFISKNFVYRTLPFDQLVQRAAEEKHKEFFVSEDEKYYLRSLGEDPRKDVADIRKQFPLLKGDIKFPEFFKEEQFFSSVFRISSPGLQLWTHYDVMDNLLIQVTGKKRVVLFSPRDAQYLYLKGTKSEVLNIDNPDLAKYPLFSKARRYECSLEAGDVLFIPALWFHNVISEEFGVGVNIFWKHLPSECYDKTDTYGNKDPTAASRAAQILDRALKTLAELPEEYRDFYARRMVLHIQDKAYSKNSE
Protein: Without children, isoform C (A0A0B4K7W6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSTKMGINTGKGGVGGKKSGSGTMLPVISTVQSLASGETEARIGNLTVRRKRGRPRESGTSSPPLSMPGVHPPAQRGRPRKHAVDYSARSPSPTMSGGSSHMGIPVRRNTTTTMDFGPATVTETKIITVPPYPKAVRNVNISCKPLTVTQGEQCSPDVRDCATQTEKDYSNKVLIPVPVPIFVPQPMYMYSAPFPVPVPIPLPIPVPIFIPTTRNTAQGILKEIKKIQDKMPEDPLEAELLMMAEMVAEEKHESDSDSDNEIKPDPGLVALQYQNSLESVAQQQQQQQVVDVSGAGHNPYGDDMLQIALKMATGDYDNHHQTSTVDLETSMTANTISSQSPMGHDGMGQMGVHHLDQQHHMLDATQRTARGRKRGVGVVMDPPNRNSRSPVKRQRGGEMDHSALQQQSQQAQQPQEKPDAQMFLKYTFGVNAWKQWVMTKNADIEKSSMRRRPFKTELLQMTADELNYSLCLFVKEVRKPNGTEYAPDTIYYLVLGIQQYLYVNGRIDNIFYDPYYERFTECLDEVARKFSVLYNDSQYIVTRVEEEHLWECKQLGAHSPHVLLSTLMFFNTKHFNLTTVEEHMQLSFSHIMKHWKRSSQNSKVPGSRNVLLRFYPPQAGLDANPRKKKVYEQQENEENPLRCPVRLYEFYLSKCPESVKTRNDVFYLQPERSCVPDSPVWYSTQALGQDALQRMLHRVKMVKEINIALLTT
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (A0A8I5ZXG2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLTYYEGRAEKKYRKGFIDISKIKCVEIVKNDDGIIPCQNKFPFQVVHDANTLYIFAPSPQSRDRWVKKLKEEIKNNNNIMIKYHPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKRRPPPPIPPEEENTEEIVVAMYDFQATEAHDLRLERGQEYIILEKNDTHWWRARDKYGWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLPRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVECEETFGR
Protein: Probable aldehyde dehydrogenase (EC 1.2.1.3) (P9WNY1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- DUF779 domain-containing protein
- Acetyl-coenzyme A synthetase
- NADP-dependent alcohol dehydrogenase C
- Acetate kinase
- Probable zinc-type alcohol dehydrogenase
- Probable alcohol dehydrogenase adh
- Alcohol dehydrogenase B
- Probable alcohol dehydrogenase AdhA
- Propanal dehydrogenase
- Acylphosphatase
Sequence:
MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRIDKNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAAAIRAQEGALSQIDEDTVAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQHTKNLLVSYSDKALGFF
Protein: Uncharacterized protein (A0A1D8PPH3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- RNA polymerase-associated protein CTR9
- Cdc73p
Sequence:
MDIEERLEKAEQSDSPSLVGSSIRSADDSTHKNYIHPEKYKSSKDINKLKRYSKLNSAITASLDDLINEGALLGSEADFDKFLDQDGSVKTDAQYTPEKKVASEETDDVTSTKGDEVEVLKTQKEDKKAQVAESSPQKSSSDEKSSETESSVIESEPEISSTEDTATDNVGGKTAASSFYKQEDYSTPNLSEFQLEHDIKDHKELIDHVQSYDLQKLPNSNSSFNSKFRKDEEVVSATSSQPTLLSPAQQQRLEGGLHTPFFHTERPRSRSRSANPTSTTRDRSSSRNSTGSRKPHLARGDSYKSTHEEEPSKYELPADLAQEVDEAKEEEEPDERRSRQSKPTMGESIAAAEAKAEALGKAADPAFEADTPLTRDPSLVTTGDYTNFEVDTPKKEIPLSDNFYTARSASATNYLRSISRSRSAARNASSVVGKDEKNDSSTDALVREGALISDDPYSTIEQLDTMVEEVLHIGDNTLTSDTKSTDTKDSEKEKFVAEPKSVDKTKELETKTSEKSEESKESGVEKLKEFDTEKEISVEESKKVDDNDETDLKESKETKVEKASDKPITHEELIDEDIEKAKHQSNEKDDANTDVLAEEGALVNEDDYDLVDKKELEKEGITTEEEAPLNIKEKKSEKTVQEDVLESSVKKDDEKPILDVESKEAKKAADDEEKAASEQPPSDIVEKSSKETEEKETDETTKEELPVGTKVEDSEKDTTTLKSEVEELEKSEEQPLDIKKKEVVETKDDVATEKSKDVEQAVSSTTKETTKPEVLETEKPKPAVADDDDLDDLDISPEEIRKHLESQPVYIFTSLAGGMQVILRSNNLAAILQGNGIKFEYRDLGTDEEAKKIWKRQANGKTLPGVVRGDDYIGNWQEIEDANEEYRLRELLYETL
Protein: Vacuolar ATPase assembly integral membrane protein VMA21 (P41806)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Functions with VOA1 in assembly of the integral membrane sector (also called V0 sector) of the V-ATPase in the endoplasmic reticulum. Escorts the assembled V0 sector in COPII vesicles. Also required for normal packaging of the SNARE BOS1 and possibly the ER to Golgi transport receptor ERV29.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000255|HAMAP-Rule:MF_03058}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03058}. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Interaction partners:
- V-type proton ATPase subunit d
- V-type proton ATPase subunit c
- V-type proton ATPase subunit a, vacuolar isoform
- V-type proton ATPase subunit c'
- V-type proton ATPase subunit c''
- V0 assembly protein 1
- V-type proton ATPase subunit F
- V-type proton ATPase subunit e
- V-type ATPase assembly factor PKR1
- Vacuolar ATPase assembly integral membrane protein VPH2
Sequence:
MAVDVPRAVINKLMLFTAAMVVLPVLTFFIIQQFTPNTLISGGLAAAMANVVLIVYIVVAFREDTEDHKVDGNKKED
Protein: NPC intracellular cholesterol transporter 2 (EPV20) (Epididymal secretory protein E1) (Niemann Pick type C2 protein homolog) (P79345)
Organism: Bos taurus (Bovine)
Function: Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1 (By similarity). May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the plant sterols stigmasterol and beta-sitosterol (By similarity). The secreted form of NCP2 regulates biliary cholesterol secretion via stimulation of ABCG5/ABCG8-mediated cholesterol transport (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P61916}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P61916}. Lysosome {ECO:0000250|UniProtKB:P61916}. Note=Interaction with cell-surface M6PR mediates endocytosis and targeting to lysosomes. {ECO:0000250|UniProtKB:P61916}.
Interaction partners:
- NPC intracellular cholesterol transporter 1.
- NPC1 like intracellular cholesterol transporter 1.
- Sterol regulatory element-binding protein cleavage-activating protein
- StAR-related lipid transfer protein 3
Sequence:
MRFLTVAFLFLALSASALAEPVKFKDCGSWVGVIKEVNVSPCPTQPCKLHRGQSYSVNVTFTSNTQSQSSKAVVHGIVMGIPVPFPIPESDGCKSGIRCPIEKDKTYNYVNKLPVKNEYPSIKVVVEWELTDDKNQRFFCWQIPIEVEA
Protein: Homeobox protein TGIF2LX (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, X-linked) (TGIF-like on the X) (Q8IUE1)
Organism: Homo sapiens (Human)
Function: May have a transcription role in testis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Polyadenylate-binding protein 5
- Homeobox protein TGIF2LY
- Protocadherin-11 X-linked
- Transforming growth factor-beta-induced protein ig-h3
Sequence:
MEAAADGPAETQSPVEKDSPAKTQSPAQDTSIMSRNNADTGRVLALPEHKKKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILPDMLQQRRNDPIIGHKTGKDAHATHLQSTEASVPAKSGPSGPDNVQSLPLWPLPKGQMSREKQPDPESAPSQKLTGIAQPKKKVKVSVTSPSSPELVSPEEHADFSSFLLLVDAAVQRAAELELEKKQEPNP
Protein: Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form] (Q9UIQ6)
Organism: Homo sapiens (Human)
Function: Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11389728}; Single-pass type II membrane protein {ECO:0000269|PubMed:11389728}. Note=In brain only the membrane-bound form is found. The protein resides in intracellular vesicles together with GLUT4 and can then translocate to the cell surface in response to insulin and/or oxytocin. Localization may be determined by dileucine internalization motifs, and/or by interaction with tankyrases.; SUBCELLULAR LOCATION: [Leucyl-cystinyl aminopeptidase, pregnancy serum form]: Secreted. Note=During pregnancy serum levels are low in the first trimester, rise progressively during the second and third trimester and decrease rapidly after parturition.
Interaction partners:
- TBC1 domain family member 4
- Poly [ADP-ribose] polymerase tankyrase-2
- Solute carrier family 2, facilitated glucose transporter member 4
- Poly [ADP-ribose] polymerase tankyrase-1
- Protein limb expression 1 homolog
- Oxytocin-neurophysin 1
- Ras-related protein Rab-14
- Insulin
- 182 kDa tankyrase-1-binding protein
- Angiotensinogen
Sequence:
MEPFTNDRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGEHEMEEDEEDYESSAKLLGMSFMNRSSGLRNSATGYRQSPDGACSVPSARTMVVCAFVIVVAVSVIMVIYLLPRCTFTKEGCHKKNQSIGLIQPFATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSAVSSQEKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEKLGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMKLFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSEDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLTWWL
Protein: Gap junction delta-2 protein (Connexin-36) (Cx36) (Gap junction alpha-9 protein) (Q9UKL4)
Organism: Homo sapiens (Human)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Interaction partners:
- Tight junction protein 1
- Gap junction alpha-1 protein
- Gap junction gamma-1 protein
- Mitogen-activated protein kinase 3
- Cyclin-dependent kinase 1
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 7
- Gap junction beta-2 protein
- Tight junction protein 2
- Multiple PDZ domain protein
Sequence:
MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSGLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNKDLPRVSVPNFGRTQSSDSAYV
Protein: Melanoma-associated antigen 9 (Cancer/testis antigen 1.9) (CT1.9) (MAGE-9 antigen) (P43362)
Organism: Homo sapiens (Human)
Function: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Interaction partners:
Sequence:
MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDSKEEEVSAAGSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYILVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYGEPRKLLTQDWVQENYLEYRQVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV
Protein: Peptidyl-tRNA hydrolase ArfB (PTH) (EC 3.1.1.29) (Alternative ribosome-rescue factor B) (P40711)
Organism: Escherichia coli (strain K12)
Function: Rescues stalled ribosomes. Can hydrolyze peptidyl-tRNA on ribosomes stalled by both non-stop mRNAs and mRNAs that contain rare codon clusters or ribosomes stalled in the middle of mRNA. First identified as a complementary ribosome rescue system when the stalled ribosome cannot be rescued by the SsrA(tmRNA)-SmpB quality control system or the alternative ribosome-rescue factor A (arfA).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Alternative ribosome-rescue factor A
- Large ribosomal subunit protein bL27
- Large ribosomal subunit protein bL21
- Large ribosomal subunit protein bL19
- Peptide chain release factor RF1
- SsrA-binding protein
- Large ribosomal subunit protein bL33
- Peptide chain release factor RF2
- Small ribosomal subunit protein bS16
- Small ribosomal subunit protein uS12
Sequence:
MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIRASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAMIKELTTEKKARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE
Protein: Phosphoglycerate mutase-like protein 2 (F4IBB2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in carbohydrates metabolism.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Uncharacterized protein
- Cofactor-independent phosphoglycerate mutase
- Phosphoglycerate mutase-like protein 4
- 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1
- Metal-independent phosphoserine phosphatase
- Phospholipid hydroperoxide glutathione peroxidase
- Amino-acid permease BAT1
- 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1
- Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2
Sequence:
MIHQSMTSNLSFYISSVSHLSSPLPSLSRLSLRCCSSLPAHDMETKPSQGLYPLHRCKTIHLVRHAQGIHNVEGEKNHKAYLSEDLFDAHLTPLGWQQVDNLHKHVNASGISNRIELVVVSPLLRTLQTAVGTFGGEGYKDGVNTPLLMTAGAGNSDRPAISRLNRPPFIAVESCREHLVCLLFYLLHDWHFLEMKTFAMFLVQGVHPCDRRSNITKYRELFPAIDFSLIETDEDVLWKPDIREEDKDIATRGVKFFNWLSTRKEKEIAVVTHSGFLYQTLNSFGNDCDPSVKNEISKKFVNCELRSFVLVDKCMSSSDPPMTNYPGTILTGEDASSDIADQK
Protein: Probable transporter MCH4 (Q08268)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable transporter. Does not act in the transport of monocarboxylic acids across the plasma membrane.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Uncharacterized protein YOL118C
Sequence:
MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLARERTKPVVQPFKSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF
Protein: RNA helicase (EC 3.6.4.13) (Q8IKP1)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Uncharacterized protein
- Nucleoporin NUP221, putative
Sequence:
METQEAPNIETKDEKQNGDADIIVTNKDEQSSKKKEENSNDDNKPGDVKEPADDNKPSDKKQPDDDNKYSDKKQPDDDNKSSDKKQPADDNKDNAGSDNVMNMFLNYLQKNKDDPAILQTMMSMMSGQNKNNLSASDLLSFTNSLNKKGEEKGEKNKEEEKKENEMPSEDLKNPSELITKEEKNEDNISTSDTQNVSNNIITKSESDTKQNNDSSSNNNNNNNYSVSEKVSGEENTNNNNNEEVVKKKHSVLVEDNDDYEIEETVEPKEPVEEEAISIIENININNKEKEKKGNDLFSPTSSSIENNNNDNNKESSDFKLYHSKNTWEELKIDNELIQILTYLKFLGPSKIQAYALPIILSSNKNLIAQSQNGSGKTLTFVIAMLCKINRTLSSLQAVCICPTRELSQQNYDVVCNFTKYLNVKVFLAVPLCERYNKSGGYQIYVGTPGKTLDFLKRKFIDTKNIKLFVLDEADDLIDIKNNMSSQVETIKRFLPRSCQILLFSATYNDSVRKFADQFAPKATKISVRQEDLTLKCVKQYYLITENDEQKYYYLSELYCSMTISQCVIFVNSKKSAYNLYNFMTENSHNVTLICADSIISRFTKNQIQKANVLGMDPKTRDTLMADFKKGISKVLICTDLLSRGIDVPSISLVINFDLPYIYQGRIGDTLNNTSNQRVNMETYIHRIGRTGRFGTKGMAINFISKNQMSHIKQIEEYYKCSIADLEFDSELMITSLTKLKN
Protein: D-ribose-binding periplasmic protein (T2K10.6 protein) (Q9ZUJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At3g10120
- At1g64700
- At3g03280
- 6,7-dimethyl-8-ribityllumazine synthase
- Uncharacterized protein At5g66580
- At1g71015
- Emb|CAB85509.1
- 6,7-dimethyl-8-ribityllumazine synthase
- Uncharacterized protein At5g17350
- DUF4228 domain protein
Sequence:
MGNCQAVDAAALVLQHPDGKIDRYYGPVSVSEIMRMYPGHYVSLIIPLPEKNIPATTTTTDDKSERKVVRFTRVKLLRPTENLVLGHAYRLITSQEVMKVLRAKKYAKTKKHQSETSKEKKKPSSEKKIDEESDKNQNLETKDEKQRSVLTNSASSRSKTWRPSLQSISEATS
Protein: Heavy metal-associated isoprenylated plant protein 6 (AtHIP06) (Cadmium induced protein CdI19) (Q9LZF1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Heavy-metal-binding protein. Involved in the maintenance of heavy metal homeostasis and/or in detoxification.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12383082}.
Interaction partners:
- Heavy metal-associated isoprenylated plant protein 43
- Heavy metal transport/detoxification superfamily protein
- Large ribosomal subunit protein uL24y
- Small polypeptide DEVIL 11
- Late embryogenesis abundant
- CLAVATA3/ESR
- Disease resistance-like protein DSC2
- Dentin sialophosphoprotein-like protein
- Small ribosomal subunit protein mS78
- Small polypeptide DEVIL 4
Sequence:
MGEKKEETATKPQGEKKPTDGGITTVVMKLDMHCEGCGKKIKRIFKHFKGVEDVKIDYKSNKLTVIGNVDPVEVRDKVADKIKRPVELVSTVAPPKKETPPSSGGAEKKPSPAAEEKPAEKKPAAVEKPGEKKEEKKKEEGEKKASPPPPPKESTVVLKTKLHCEGCEHKIKRIVNKIKGVNSVAIDSAKDLVIVKGIIDVKQLTPYLNEKLKRTVEVVPAKKDDGAPVAAAAAAPAGGEKKDKVAGEKKEIKDVGEKKVDGGGEKKKEVAVGGGGGGGGGGGDGGAMDVKKSEYNGYGYPPQPMYYYPEGQVYGQQHYMMQGQSSQSYVQEPYSNQGYVQESYMNQGYGQGYGQEAPPPPYMNQQGYADPYGHMRAPELFSDENPNGCSVM
Protein: Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b) (Q9Z0F8)
Organism: Mus musculus (Mouse)
Function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Plays a role in the proteolytic processing of ACE2 (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called notch extracellular truncation (NEXT). Plays a role in hemostasis through shedding of GP1BA, the platelet glycoprotein Ib alpha chain. Mediates the proteolytic cleavage of LAG3, leading to release the secreted form of LAG3. Mediates the proteolytic cleavage of IL6R, leading to the release of secreted form of IL6R (By similarity). Mediates the proteolytic cleavage and shedding of FCGR3A upon NK cell stimulation, a mechanism that allows for increased NK cell motility and detachment from opsonized target cells.
Subcellular location: [Isoform Long]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform Short]: Secreted.
Interaction partners:
- Metalloproteinase inhibitor 3
- Neurogenic locus notch homolog protein 1
- Disintegrin and metalloproteinase domain-containing protein 10
- Neurogenic locus notch homolog protein 2
- Tumor necrosis factor
- Neurogenic locus notch homolog protein 3
- Neurogenic locus notch homolog protein 4
- Inactive rhomboid protein 2
- Angiotensin-converting enzyme 2
- L-selectin
Sequence:
MRRRLLILTTLVPFVLAPRPPEEAGSGSHPRLEKLDSLLSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMDSASVRIIKPFPAPQTPGRLQALQPAAMMPPVPAAPKLDHQRMDTIQEDPSTDSHADDDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
Protein: Heat-inducible transcription repressor (Q9LZN4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAYRRRQGIGKFATFKEEVDRLPPESITAVKDRSPPARSSPAFDQPRSKNFTTEPKGLWGVIAQKAKSVIEDDKSSDRSTTASQSRFSYLSDEGFKKMDNPKLRRGLDKLTSSLNQIGDTFEKAFEDGRTLVENKTADIIQETRKLQTRRRGTGGEDENQNQSYGVSSSWKKSPEQPMQLNHIEHETQLKASRDVAMATAAKAKLLLRELKTVKADLAFAKERCAQLEEENKHLRESHREKGSNPADEDLIRLQLESLLAEKARLAHENSVYARENRFLREIVEYHQLTMQDVVYIDEGSEEVTQVSPFVSTLMTSSPADRSQSPPSQEMIKEMLVVAEESSVCASVVSVS