wanglab/gogpt-training-data huggingface dataset:
Protein: Thyroid peroxidase (TPO) (EC 1.11.1.8) (P09933)
Organism: Sus scrofa (Pig)
Function: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Thyroglobulin
- Thyrotropin receptor
Sequence:
MGARAVLGVTLAVACAGAFFASILRRKDLLGGDTEASGVAGLVEASRLLVDEAIHTTMRRNLRKRGIFSPSQLLSFSKLPEPTSRTASRAAEIMETAVQEVKRRVCRRRDTDQLPTDVLSEELLSTIANLSGCLPHMLPPSCPHTCLANKYRLITGACNNRDHPRWGASNTALARWLPPAYEDGVTEPRGWNPHFLYNGLPLPPVREVTRQVIHVSNEAVTEDGQYSDLLMAWGQYIDHDIAFTPQSTSKAAFAGGADCQLTCENRSPCFPIQLPTNASGAAGATCLPFYRSSAACGSGRQGALVGNLSWAAPRQQMNGLTSFLDASTVYGSSPAQEQRLRNWTSAEGLLRVNTRHRDAGRAFLPFAPPPAPPACAPEPGTPAARAPCFLAGDSRASEVPGLTALHTLWLREHNRLAAAFKALNAHWSADTVYQEARKVVGALHQIVTLRDYVPKILGAEAFGQHVGPYQGYDPAVDPTVSNVFSTAAFRFGHATIHPLVRRLDARFQEHPGSHLPLRAAFFQPWRLLREGGVDPVLRGLLARPAKLQVQDQLMNEELTERLFVLSNSGTLDLASINLQRGRDHGLPGYNEWREFCGLSRLETWADLSAATANGRVADRILGLYQHPDNIDVWLGGLAESFLPGARTGPLFACIIGKQMRALRDGDRFWWENPGVFTEAQRRELSRHSMSRVICDNSGLSHVPLDAFRVGQWPQEFEPCASIQGMDLGAWREAPPSGDACGFPDPVEDGGFLLCEERGQRVLVFSCRHGFRLRGPAQITCTPRGWDSPPPLCKDINECEDETDPPCHASARCKNTKGGVLCECSDPLVLGEDGRTCVDAGRLPRASVVSIALGAVLVCGLAGLAWTVVCRWTHADARPLLPVGEGEGDGKSPSLPLPGCGNRRDVGAAPALEVEQDLSCGSRGLCE
Protein: dTDP-4-amino-4,6-dideoxyglucose formyltransferase (dTDP-Qui4N formyltransferase) (EC 2.1.2.-) (Sugar N-formyltransferase Rv3404c) (P9WKZ3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Sugar N-formyltransferase that catalyzes the conversion of dTDP-4-amino-4,6-dideoxyglucose into dTDP-4-formamido-4,6-dideoxyglucose using N(10)-formyltetrahydrofolate as the carbon source. Plays a role in virulence. Has no activity on dTDP-3-amino-3,6-dideoxyglucose, dTDP-3-amino-3,6-dideoxygalactose, UDP-4-amino-4-deoxyarabinose, and GDP-4-amino-4,6-dideoxymannose.
Interaction partners:
- Putative methyltransferase Rv1407
- Uncharacterized protein Rv3403c
- Serine/threonine protein phosphatase PstP
- Transcription antitermination protein NusB
Sequence:
MTILILTDNVHAHALAVDLQARHGDMDVYQSPIGQLPGVPRCDVAERVAEIVERYDLVLSFHCKQRFPAALIDGVRCVNVHPGFNPYNRGWFPQVFSIIDGQKVGVTIHEIDDQLDHGPIIAQRECAIESWDSSGSVYARLMDIERELVLEHFDAIRDGSYTAKSPATEGNLNLKKDFEQLRRLDLNERGTFGHFLNRLRALTHDDFRNAWFVDASGRKVFVRVVLEPEKPAEA
Protein: Transcription factor glial cells missing (Protein glide) (Q27403)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor that induces gliogenesis. It determines the choice between glial and neuronal fates. Also has a role in the differentiation of the plasmatocyte/macrophage lineage of hemocytes.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00245, ECO:0000269|PubMed:7553844}.
Interaction partners:
- GH05443p
- GATAe, isoform A
Sequence:
MVLNGMPITMPVPMPVPMPVPSPPATKSRVAIDWDINDSKMPSVGEFDDFNDWSNGHCRLIYSVQSDEARKHASGWAMRNTNNHNVNILKKSCLGVLLCSAKCKLPNGASVHLRPAICDKARRKQQGKQCPNRNCNGRLEIQACRGHCGYPVTHFWRRDGNGIYFQAKGTHDHPRPEAKGSTEARRLLAGGRRVRSLAVMLARESALSDKLSSLRPTKRQAKTQSIQESKRRRMGASDVLETKQELVVPPTTYLPTSTPTHSTNFNQSQGSYVPAGQGSVISQWNREIHYETEDPCYANGMYSYDMLHSPLSAHSSTGSYYQENKPQQLQHSQYQQQLSPQQHVPVSYDPSQPISSSLQCGMPSYEICDDTSSLTSSSGYCSEDYGYYNGYLPNSLDVSNGSQSQNLSQDASFYTTSSEIFSVFESTLNGGGTSGVDLIYDEATAYQQHQQQGTFPHLTNYQQEPQDQMQSADYYYSNTGVDNSWNIQMDATYHPVNSTDPIYC
Protein: FERM domain-containing protein 7 (A2AD83)
Organism: Mus musculus (Mouse)
Function: Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.
Subcellular location: Cell projection, neuron projection {ECO:0000269|PubMed:19892780}. Cell projection, growth cone {ECO:0000269|PubMed:19892780}. Note=In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones. {ECO:0000269|PubMed:19892780}.
Interaction partners:
- G-protein coupled receptor 143
Sequence:
MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCGHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEVVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDFHEETVRKHLVQTQYLPSQASLESKIMQFHQQHIGRSPAESDILLLDIARKLDMYGIRPQPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGKKGRLKSLPFERKQYPSQYHERQCRSSPDILSDVSKQVEDLRLTYGSSYYRNVNGVHASESMLDSRRRNSAVEVTFAAELEHSKPEAEATSLHPSQSSSSFTFIYADPVFNTDPEPIEFFEERSPLSSFQTTSKFADSHTSKASPARQLTYTDVPYIPCTSQKVDIMPPQVFFYVDKPPQVPRRSLIMAEENMRPDSYVDHSAIKPAKRSPRNMRIKSLQQDLQELQEAMARTSGRSNINVEPEEEDPHLDDAFAYNLQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALTRKTDLFACTFAEQEFPTVLIDQSSAERYVASESSDSESEIIKPDYYFLYGKGTKSPRARIRLSSGSLQLEEEDETISFATPGAEDRTLLKPCNYFLA
Protein: Tubulin folding cofactor B (K7EK42)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MEVTGVSAPTVTVFISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVDDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVSQISSLATGLVSAMMSHWGKMMAV
Protein: Pleckstrin homology domain-containing family H member 2 (Q8C115)
Organism: Mus musculus (Mouse)
Function: In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia.
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17251388}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=Localizes to the slit diaphragm and foot process of podocytes. Localization to peripheral regions of lamellipodia seems to be dependent on PI3K (By similarity). {ECO:0000250}.
Interaction partners:
Sequence:
MEEPSEPEGLIDWKERCVALEAQLMKFRVQASKIRELLADKMQQLERQVIDAERQAEKAFQEVQVMEEKLKAANIQTSESETRLYKKCQDLESVMQEKDDIIQNLALRLEEQKQVRIQEAKIIEEKAAKIKEWVTVKLNELEVENQNLRFINQTQTEEIRAIQSKLQELQEKKISCVSSPKTSEGQRNLTFGCFLSRAKSPPCVVRCEEVSKMASNEPEITEGRCVEEMEIAEKPADNQVQENSRSQRKLHETSCSSEQNQKTRASFAMDGGTSQNSGVPVSDWSSDEDDGSKGRSKSRCTSTLSSHTSEEGGQCGRLGSEAYLTASDDSSSIFEEETFDGNRPEQKKLCSWQQKAPWKAQGNLAKGRSQSGVKEQDSSSDELNKKFHSQRLDYTSSSSEANTPSPILTPALTPRYPNSLPGKGGAPLVPPPFQPPPKLRVPNVFSISVALTKRHLSQPQLCSDRMFGTNRNAISMIRPLRPQETDLDVVDGDGAEAVNRMDTGCDDGLFSYDSQDPPPCADDQENSEAPKKAPCNKPPTPPLHRFPSWESRIYAVAKSGIRVSEAFNMEHANKNSADILSYSAASLYTSLIYKNMTTPVYTTLKGKATQISSSPFLDDSSGSDEEDSSRSSSRLSESDARSRSGPSSPRAMKRGVSDSSAASESDYAIPPDAYPIDAECSQPEQKLLKTCLASCDNGKNEPLEKSGYLLKMSVRVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLATEKHTYYLTADSPNILEEWIKVLQSVLRVQAANPLCLQPEGKPAVKGLLTKVKHGYSKRVWCMLVGKVLYYFRNQEDKFPLGQLKLWEAKVEEVDRSCDSDEDYETRGCYLLSTHYTIIVHPKDQGPTYLLIGSKHEKEAWLYHLTVAAGSNNINVGSEFEQLVCKLLNIEGEPSSQIWRHPMLCHSKEGILSPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHISLAQSALQVCLTHPELQNEICCQLIKQTRRRQLQNQPGPLQGWQLLALCVGLFLPHHPFLWLLQLHLQRNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSRPFSIPVHFMNGLYQVVGFDASTTVEEFLNTLNQDTGMRKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKEQQPGKCEGSRTVRLTYKNRLYFSVQARGETDREKTLLLYQTNDQIINGLFPLNKDLALEMAALLAQVDIGDFERPFSTPAGPVTNQCKANQTLKQVIERFYPKRYREGCSEEQLRQLYQRLSTKWMALRGHSAADCIRIYLTVARKWPFFGAKLFFAKPIAPSSLGNNCVWLAVHENGLSILEYTSMRLVTSYMYKGLMTFGGYQEDFMVVVSTQSKDRPTEKLLFAMAKHKILEITLLIASYINSFHQQKTTFHHLSAPALLSPRTQAPQARVMGSQPPLSNSRPTKGPTLL
Protein: Protein kinase C alpha type (EC 2.7.11.13) (G1N621)
Organism: Meleagris gallopavo (Wild turkey)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004318}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004318}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
NAFCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLLHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTGDKLEVTVREAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTFRSTLNPHWNESFTFKLKPTDKDRRLSVEVWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPDADEDGNAELRQKFEKAKLGPAGNKVITPSEDRSSSVPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKNTEELYAIKILKKDVVIQDDDVECTMVEKRVLALQDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISVGLFFLHNRGIVYRDLKLDNVMLDSEGHIKIADFGMCKEHMLDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGLEGERDIREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPLLENVA
Protein: AT03573p (Lectin-46Cb) (Q7JY62)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform A
- Uncharacterized protein, isoform B
- Accessory gland protein Acp36DE
- Antares, isoform B
- Seminase
- Accessory gland-specific peptide 70A
- Accessory gland protein Acp29AB
- Aquarius
- Accessory gland protein Acp62F
- Seminal metalloprotease 1
Sequence:
MKHLLTALVALLSILPRGELLGSGPPCPRRYLRRINGKCYYFSVKKMNWFGALNNCLRKGLTLADLSNQRDFDGAIGFLSGLGNTEDFWFGGNDLYHEGRFQYISNGRLVRYYSNYSNVLPLEHSECDDCLEVRIRSEINMVSADNCHERQYFICSERYCQGTDSGKKPKHHSHEHLHHFHHDIGGSAEGEDDGDGDGDHDRQDPIASGSVEHPEPDSEDAVGALDVPDDDQPGQNGVSVTPGAEETNTVGGTGEPGATATPAAGAEAVSPAAEGAAPAGAAPAAEGAATPAADGATPAPTPAPGAEAPAAAAAETPAPPAA
Protein: Glyceraldehyde-3-phosphate dehydrogenase 3 (GAPDH 3) (EC 1.2.1.12) (Triose-phosphate dehydrogenase 1) (P00359)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11502169}. Mitochondrion {ECO:0000269|PubMed:16823961}.
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Glyceraldehyde-3-phosphate dehydrogenase 1
- Phosphoglycerate kinase
- Triosephosphate isomerase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Actin
- Transaldolase
- Enolase 1
- Glucose-6-phosphate 1-dehydrogenase
Sequence:
MVRVAINGFGRIGRLVMRIALSRPNVEVVALNDPFITNDYAAYMFKYDSTHGRYAGEVSHDDKHIIVDGKKIATYQERDPANLPWGSSNVDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSLTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSHSSIFDASAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKA
Protein: Triggering receptor expressed on myeloid cells 1 (A0A8I5ZYI0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MRKAGLWGLLLVFFVSGSSGVSVPDIIPTTKPTEVPVLITTKHSTPTRSLPKSTAVVSSPDPGVTINNGTDPTSVSTYNVVVPVVCGLLIKTLIFFVLFVVTKRSFG
Protein: TNF receptor-associated factor (Q7T1K2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|PIRNR:PIRNR015614}.
Interaction partners:
- Interleukin-1 receptor-associated kinase 4.
- Myeloid differentiation primary response protein MyD88
- Neutrophil cytosolic factor 1.
- Interleukin-1 receptor-associated kinase 1
Sequence:
MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMCSLVGRQRQEILELRREMEELSVSHDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASIEIPQKIMA
Protein: GEO12025p1 (IP04426p) (Uxt prefoldin-like subunit, isoform A) (Uxt prefoldin-like subunit, isoform B) (Q9VJP9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Probable prefoldin subunit 6
- IP05962p
- Probable prefoldin subunit 2
- IP21091p
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- RNA polymerase II-associated protein 3
- PIH1 domain containing 1, isoform D
- Unconventional prefoldin RPB5 interactor-like protein
- Probable prefoldin subunit 5
- Prefoldin subunit 3
Sequence:
MQVNPKHNTEAHRQAEQDANKARITQIEEFINEVLKEDLRELEKCIGQYNEEIMEYVQLKNTLQTFDTHLPDGYKTQVNIGSNVFMQARVRKMDSILVDVGKNVFLDMSIPDAERFCDTRVKILTKQSDVLRDESVKKRAQIKMALIAISERTKLIQQDESK
Protein: FI02822p (Leash) (Q9VGU4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Myopic
- Transcriptional coactivator yorkie
Sequence:
MESERLRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTGGAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEELFGLANAPPGTPK
Protein: Serine/threonine protein phosphatase, putative (Q583T9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Protein phosphatase methylesterase 1
- SAM domain-containing protein
- MIF4G domain-containing protein
- Uncharacterized protein
- TAP42-like protein
- Serine/threonine-protein phosphatase 2A activator
- Uncharacterized protein
Sequence:
MTSSTLLEKLSSLKLSEGARVGGRTFRQGVMSPGTIANVTTTATTNINNTNVASAFASLMEKRQPTGSPAENEGPLRGLIIGSDGSGNNNNSSSNNNNNNNNNNSRSMKHSSNNSSTNSGNDKPIETQAPHRSGVEGSAGKAARKLRSSPRTHQLPDEMREKTSHISAVPRSVALALASASVGVTEQPSVTVEQLMRAAPSANVSSVTSPPRCVPTLPVEPMVVVDREGGPDAVRLATLVSGDPSNPKLIDPIDNVNAHKPIIRTVPPCDYRYIIVGDVHGCPEQLEELLLKVEFQQGKDCLIHVGDLVNKGPDSLAVVQLVQAKGAIGVLGNHDFTLLNCIARVKGKALSQQEEVDPVMRLASTFPQGCEDYIRSLPHILRIPQYNVIVVHAGLNVENSLEKQNVHEIMHLRRLERYTESSNNNNNNCGGKQQRNEKQRLRAVVKGSRGQPWGELWTGPECVVFGHDARAGLQELPFAYGIDTGCVYGGQLTAVVYGRDSPKGKLVSVTGLPKDANERRGLPPPAADVYEKYAEELERLILRPTPRATPAIIGYMQKPTFLSAPPPGSPAASTGSVINNSLRPDSCCSLPAASPSLSARATVRSSGVEQETLLSLLRAGEIRAVMTLMRLPAYESMWLNLLCSEVEGCTESFWIPFVKGVLDGLLNTRQNGEGDDYVEDLLQLVLEACDEFCSVREMAIPQLRKLQQRAEGGDFALPKATVKMLKLTVSPQNA
Protein: Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic (RA) (RuBisCO activase) (P10896)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
Subcellular location: Plastid, chloroplast stroma. Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:16461379}.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 6 homolog
- Proteasome subunit alpha type-3
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- 26S proteasome regulatory subunit 6B homolog
- Proteasome subunit beta type-4
- 26S proteasome non-ATPase regulatory subunit 11 homolog
- 26S proteasome regulatory subunit RPN13
- 26S proteasome regulatory subunit 4 homolog B
- Proteasome subunit beta type-6
- 26S proteasome regulatory subunit 4 homolog A
Sequence:
MAAAVSTVGAINRAPLSLNGSGSGAVSAPASTFLGKKVVTVSRFAQSNKKSNGSFKVLAVKEDKQTDGDRWRGLAYDTSDDQQDITRGKGMVDSVFQAPMGTGTHHAVLSSYEYVSQGLRQYNLDNMMDGFYIAPAFMDKLVVHITKNFLTLPNIKVPLILGIWGGKGQGKSFQCELVMAKMGINPIMMSAGELESGNAGEPAKLIRQRYREAADLIKKGKMCCLFINDLDAGAGRMGGTTQYTVNNQMVNATLMNIADNPTNVQLPGMYNKEENARVPIICTGNDFSTLYAPLIRDGRMEKFYWAPTREDRIGVCKGIFRTDKIKDEDIVTLVDQFPGQSIDFFGALRARVYDDEVRKFVESLGVEKIGKRLVNSREGPPVFEQPEMTYEKLMEYGNMLVMEQENVKRVQLAETYLSQAALGDANADAIGRGTFYGKGAQQVNLPVPEGCTDPVAENFDPTARSDDGTCVYNF
Protein: Shk1 kinase-binding protein 5 (Q9US59)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Stimulates catalytic function of the p21-activated kinase homolog shk1.
Interaction partners:
- Protein phosphatase 2C homolog 1
- Serine/threonine-protein kinase shk1/pak1
- MAP kinase kinase kinase mkh1
- Protein arginine N-methyltransferase skb1
- Shk1 kinase-binding protein 15
Sequence:
MAEETEEDYLVVGRDYLYPPDHELHYGFHARVIEEEEERFVDDTFDETIEGSDDSESIDDTEVFYDAEESESTHPSASFNVLADAVALYDFEPLHDNELGFTTGQRLCILSESSDGWLIAYDDASGRSGLVPETFVKLEV
Protein: Nucleic acid binding/RNA binding protein (Q84K41)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein STABILIZED1
- U2 small nuclear ribonucleoprotein A'
- DNA-damage-repair/toleration protein 111
- At2g32600/T26B15.16
- Nuclear protein-like
- DEAD-box ATP-dependent RNA helicase 42
- DEAD-box ATP-dependent RNA helicase 45
- PHD finger-like domain-containing protein 5B
- PHD finger-like domain-containing protein 5A
- Small nuclear ribonucleoprotein Sm D2
Sequence:
MVGGVEELSIEQLASSISTYKEQLEQVRQLLSEDPRNSEYADMEKELKEVIALTEEVLATAKQNEISLSDAGVSAEATPGSPDLEGAWEKTGLRNDPIHEGKFPVGTKVQAVFSDDGEWYDATIEAHTANGYFVAYDEWGNKEEVDPDNVRPIEQNAIVEAERLAQATKNALKRKIEKAASSDYQTKTLPAKLKIDPNDPEDVKIAKRKKIHAFKSKARFEQLEVVQNKKQNDWQQFQTTKAKTKKVGFFTGRKKESIFKSPEDPFGKVGVTGSGKGLTDFQKREKHLHLKSGNAEGTDE
Protein: Large ribosomal subunit protein eL14 (60S ribosomal protein L14) (Q63507)
Organism: Rattus norvegicus (Rat)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P50914}.
Interaction partners:
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein eL15
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein eS1
Sequence:
MVFRRFVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAALLKASPKKAAVAKAAIAAAAAAKAKVPAKKATGPGQKAAAQKASAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA
Protein: Tetraspanin-7 (Q9SUD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the regulation of cell differentiation.
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Tetraspanin-14
- Protein TORNADO 1
Sequence:
MVQCSNNLLGILNFFTFLLSIPILSAGIWLGKNAATECERFLDKPMVVLGIFLMFVSIAGLVGACCRVSCLLWLYLFAMFLLILLGFCFTIFAFAVTNRGAGEVISDRGYKEYHVADYSNWLQKRVNNAKNWERIRSCLMYSDVCSTYRTRYASINVEDFYKSNLNALQSGCCKPSNDCNFTYVNPTTWTKTPGPYKNEDCNVWDNKPGTLCYDCEACKAGLLDNIKNSWKKVAKVNIVFLIFLIIVYSVGCCAFRNNRKRSW
Protein: Sporulation initiation inhibitor protein Soj (EC 3.6.4.-) (Suppressor of spo0J) (P37522)
Organism: Bacillus subtilis (strain 168)
Function: Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of Spo0A.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18854156}. Note=Most protein localizes to the cell septa, with faint cytoplasmic foci also seen; requires Spo0J for correct localization, in an spo0J deletion only associates with the nucleoid, requires minD for association with the septa and foci formation. {ECO:0000269|PubMed:18854156}.
Interaction partners:
- Stage 0 sporulation protein J
- Chromosomal replication initiator protein DnaA
- Nucleoid occlusion protein
- Cell division protein FtsZ
- Chromosome partition protein Smc
- DNA translocase SpoIIIE
- Chromosome-anchoring protein RacA
- Sporulation inhibitor of replication protein SirA
- Replicative helicase loading/DNA remodeling protein DnaD
- Beta sliding clamp
Sequence:
MGKIIAITNQKGGVGKTTTSVNLGACLAYIGKRVLLVDIDPQGNATSGLGIEKADVEQCVYDILVDDADVIDIIKATTVENLDVIPATIQLAGAEIELVPTISREVRLKRALEAVKQNYDYIIIDCPPSLGLLTINALTASDSVVIPVQCEYYALEGLSQLLNTVRLVQKHLNTDLMIEGVLLTMLDARTNLGIQVIEEVKKYFRDKVYKTVIPRNVRLSEAPSHGKPIILYDPRSRGAEVYLDLAKEVAANG
Protein: 10 kDa heat shock protein, mitochondrial (HSP10) (10 kDa chaperonin) (P38910)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
Subcellular location: Mitochondrion matrix.
Interaction partners:
- Heat shock protein 60, mitochondrial
- GrpE protein homolog
- Mitochondrial chaperone TCM62
- ATP-dependent molecular chaperone HSC82
- ATP-dependent molecular chaperone HSP82
- Import motor subunit, mitochondrial
- Heat shock protein 78
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit zeta
- T-complex protein 1 subunit delta
Sequence:
MSTLLKSAKSIVPLMDRVLVQRIKAQAKTASGLYLPEKNVEKLNQAEVVAVGPGFTDANGNKVVPQVKVGDQVLIPQFGGSTIKLGNDDEVILFRDAEILAKIAKD
Protein: Lymphotoxin beta receptor (F5H6F8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMS
Protein: Kappa-casein (A3FJ56)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
RCEKDERFFSDKIAKYIPIQYVLSRYPSYGLNYYQQKPVALINNQFLPYPYYAKPAAVRSPAQILQWQVLSNTVPAKSCQAQPTTMARHPHPHLSFMAIPPKKNQDKTEIPTINTIASGEPTSTPTIEAVESTVATLEASPEVIESPPEINTVQVTSTAV
Protein: DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) (O55230)
Organism: Mus musculus (Mouse)
Function: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Chromosome, telomere {ECO:0000269|PubMed:15109494}.
Interaction partners:
- DNA repair protein XRCC2
- DNA repair protein RAD51 homolog 3
- DNA repair protein RAD51 homolog 2
- DNA repair protein XRCC3
- Breast cancer type 2 susceptibility protein homolog
- Fanconi anemia group M protein homolog
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- DNA repair protein RAD52 homolog
- Breast cancer type 1 susceptibility protein homolog
- Double-strand break repair protein MRE11
Sequence:
MGMLRAGLCPGLTEETVQLLRGRKIKTVADLAAADLEEVAQKCGLSYKALVALRRVLLAQFSAFPLNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCVAANVAHSLQQNVLYVDSNGGMTASRLLQLLQARTQDEEKQASALQRIQVVRSFDIFRMLDMLQDLRGTIAQQEATSSGAVKVVIVDSVTAVVAPLLGGQQREGLALMMQLARELKILARDLGVAVVVTNHLTRDWDGRRFKPALGRSWSFVPSTRILLDVTEGAGTLGSSQRTVCLTKSPRQPTGLQEMIDIGTLGTEEQSPELPGKQT
Protein: Daisho1 (Immune-induced peptide 4) (DIM-4) (P82705)
Organism: Drosophila melanogaster (Fruit fly)
Function: Peptide which plays a role in the humoral immune response to a subset of filamentous fungi, including F.oxysporum and F.verticillioides.
Subcellular location: Secreted {ECO:0000269|PubMed:16510152, ECO:0000269|PubMed:32038657, ECO:0000269|PubMed:9736738}.
Interaction partners:
- Bomanin Short 1
- Bomanin Short 3
- Bomanin Short 2
- Bomanin Bicipital 1
- Bomanin tailed 3, isoform A
- Bomanin bicipital 3, isoform A
- demerged
- Bomanin Tailed 2
- Dorsal-related immunity factor Dif
- Embryonic polarity protein dorsal
Sequence:
MKFFQAAALLLAMFAALANAEPVPQPGTVLIQTDNTQYIRTG