wanglab/gogpt-training-data huggingface dataset:
Protein: Protein CASC3 (A0A0B4KH64)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cytoplasm, Stress granule {ECO:0000256|ARBA:ARBA00004210}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}. Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
Interaction partners:
- RNA-binding protein 8A
- Eukaryotic initiation factor 4A-III
- Protein mago nashi
- Regulator of nonsense transcripts 1 homolog
- FI21285p1
- RNA helicase aquarius
- Maternal effect protein staufen
- RE04053p
- LD23870p
- LD37574p
Sequence:
MAEVEKPTAATPPTDIPQATAAPASEAPVAVTPTADTTVDVEPGTSPTQEPNSNSHPHDSEYDTASDLEGGEDYDDEESASGSASGSGSEEESETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKKVDEDRSNPQYIPKRGTFYEHDDRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGDRWSHDRFEATEQAPKSRAELLQTYGYDIRNEDAPPRARRRRRYTRGPSKYSRNWEDEQAYLKASNKERKPPRPQDFPALNERKPRGPRTSSSREEKENRRSVAAEGLVPEKQQPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQNGMEFKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQTPLSTSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQQQPLHQEQRNAPKRYSSLRRSQQEASQHLAEQQQQQMQQQLHLQQQQQQQQSQIMIQDPHVLMQIAYQQQELQAQLQTMQLGPPTAAGAVPTPPKPHAPPAAAYPQAQAAPYYVTGTEPVPVPVPQAPYVNPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQPAQPYQNYNTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPPSEKHKVKGGAKEEGISDNIDHIIDNMFVQRPSAFQATGEGATPGGGTKEEAAATPPAAEQNLQPVPATGQEXVQAYAGLPPQQQQRRGQRIAPPPSSGYSMLQPHAGYYRPPPPPH
Protein: Serine/threonine-protein kinase pakA (dPAKa) (EC 2.7.11.1) (dpak1) (Q55D99)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Regulator of the myosin II component of the cytoskeleton: required for regulation of cytokinesis. Functions during chemotaxis, required for maintaining the direction of cell movement, suppressing lateral pseudopod extension, and proper retraction of the posterior of chemotaxing cells.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:10545500}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10545500}. Note=Cytosolic in unstimulated cells, localizes to the cytoskeleton in response to chemoattractant stimulation.
Interaction partners:
Sequence:
MEEKPKSTTPPPSVSSLRQKFEQFLDKTDKGFNATRNNYRGPVSSSTGIINDKEKKSHSYFKVREEGSNKRPSSFSASNPITPSSPQSTHSSPIYRGVGYHQYSSVNSGNSYSGSGNNINNIINNSNNSNSNNLYGNNSNNQSSGSLGNFLIDKLEYSAATVTASDLKRERQQLFRNKEEFTMESSSYGGSTIGDDDLDSLNGSSSQQFNHRNSSWADRRERFIKKVMNGQFNEVQMRDELNRLRDIEADKIRAEERRTPSMNMDEFKAIEIERLRKKIYQEELVIFRQEEIEKIQREERIKIEKEYDDKSIISSQERQHIVQQIINQKEDEKGSSPPFPIPLVVNNNNNENNENDNNNNNNNNNNNNNNNNNNNNNNNKNIDLTSFNNNININSNNNEIKNNVIVDSDDEEELERLEQLRRQREIERLREEEEENEDRVERELASRRRQEEDRIKREEEEEEEEQRNYLRRLKELERIKQIEEEEEEERERQSQLQSSQQQQKSSSTQRSSNTVTSTSSSSTGGDSNPSTSQKPTNLLNLMGSNNNISNINTNILSHSIVNSSGGLPPPPPTASHVDNRSRSHTLAGESHSSENTPLVSSIDNNGVNNKMSRSHSGGALSGLALPTAPPLPNQPNVNNSNNNNNNNNINNNHNHSHNHSNNLHQSALKNSSSMSTPSISPSQAGNSATSTVPSSPISASTSMSSPTLVVSPRKDELTTSTGSTRKGSISEREDKKKVSSSSTSSSSSSNGGLSSSGKDHKKDHSSEEKEKEKKSFFNKLFSKEKKDHHSSSKSPSSGSSGGGEVDEKKKKKLSPRVGTPFNVKHDVHVNFNADTGFEGLPKEWEVLIKSNFQEPEVMQHPEEVLDVVKFHAQYQGLASAPAMHAPSIPLTDEPPVTLNDLISLDDPKKIYYNINKIGEGGAGEVFEAINSRTNQTIAIKKMKLKAQNLKTVINEIGMMKNSNHENIVQYIDSYIVADELWVAMEFMSGGCLTEVLDQYRDIQLNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREMAEGEPPYLEFPPLRALFLLTTQGLPPIRDAHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFLKRACSGPEFYKAVDAARIEKENQLQNFANLTAI
Protein: Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) (Q9W374)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uridine 5'-monophosphate synthase
- Beta-ureidopropionase
- Multifunctional protein r
- dihydropyrimidinase
- FI21247p1
- Uracil phosphoribosyltransferase homolog
- GH09623p
- Uridine phosphorylase
- FI09636p
- Uncharacterized protein, isoform B
Sequence:
MSPPQLLSKDSPDIEDLLSLNPRVKTQCSVVPTKQTKENKKHWKRNADHAAPPCTTLANDFSDIKHTTLSERGALEEAARCLKCADAPCQKSCPTQLDIKSFITSIANKNFYGAAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLQASEAGPINIGGLQQFATEVFKKMGVRQRRTPQAEANPLSQKIALVGGGPASLSCATFLARLGYRDVTIYERRSYLGGLSAAEIPQYRLPIDAVNFEIDLVRDLGVRIETGRSLGTKDLTIQGLLSTGHDAVFVGIGLPEPKLNPIFAGLQPSNGFYTSKNFLPLVSDGSKPGLCACKAAAGLPKLHGNVIVLGAGDTAFDCATSALRCGARRVFVVFRKGSSGIRAVPEEVELARDERCELLPYLSPRKVIVKDGLITAMEFCRTEQNENDEWVEDEEQTQRLKANFVISAFGSGLEDQDVKAALAPLQFRGELPVVDRVTMQSSVKQVFLGGDLAGVANTTVESVNDGKVAAWSIHCQLQGLPLDTPAALPLFYTDIDAVDISVEMCGIRFENPFGLASAPPTTSTAMIRRAFEQGWGFVVTKTFGLDKDLVTNVSPRIVRGTTSGYKYGPQQGCFLNIELISEKRAEYWLKSIGELKRDFPEKIVIASIMCSFNEEDWTELAIKAEQSGADALELNLSCPHGMGERGMGLACGQDPELVEQISRWVRKAVKLPFFIKLTPNITDIVSIAAAAKRGGADGGSAINTVQGLMGLKADSTAWPAIGKEQRTTYGGVSGNATRPMALKAISDIANRVPGFPILGIGGIDSGEVALQFIHAGATVLQICSSVQNQDFTVIEDYCTALKALLYLKANPPPVDGPFWDGQSPPTPVHQKGKPVVRLTGEGKATLGFFGPYQRQRDIKMAELRSQKGALWDAEQVKATPPASNGAPNPAPRIKDVIGAALDKIGSYNKLDNKQQKVALIDDDMCINCGKCYMTCADSGYQAIEFDKDTHIPHVNDDCTGCTLCVSVCPIIDCITMVPKKIPHVIKRGVEEKIFYTHALSQCQ
Protein: Sodium ion/proton exchanger (Eurofung) (Q5AWT0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAWDHLDIDKPHLAYMILGGFTGLFMLCSLFVKEKLYIGEATVATICGIIFGPHAANLFNPIEWGNVDKITLECSRIVLVVQCFAVGVELPKAYMERHWKSVTLLLLPVMTWGWLITSLFIWSLIKPLTWLEALVCAACVTATDPVLASSVVGKGKFAKRVPRHLRDLLSAESGCNDGMAFPFIYLSYYILHYRPDANAVSLHWFCVTILYECVFGAIFGFTIGYAARHAIRFAERKQLIDRESFLVFYFVLALFCAGSGSLLGMDDLLIGFAAGVGFSNDGWFTEKTEESHVSNVIDLLLNLAYFVYLGAILPWADYNNADLGLDAWRLVVIAILVIFFRRIPIMLLLKPIIPDVKTWREALFAGHFGPIGVGAIFACILARAELETGSTQPVVSDDLPKPHTHNYYVVQIIWPLTTFMVVASILVHGSSIAVFTLGKRINTLSITLSYTQANEEGPSWMNRLPRVQSLAKGSMSFRKADDSEGSSPNEPEYPPGTLPPIGLPGNFLRRVQEDDSGSPTGRVSTRRGRRRRRKADGAGGPISQSAIAPQRPSEVESEDAEKTVGDTESTTPSPPPATWRDAIVNVYVEGHDLIYEDKDGNVLKTEHVGHMSAEEQKRHVQAERSKLNLEFQQPPDETKPGSSEEQPTAGERLEKSIGDKAKRRRFGQWLGFGKQRSENQEQKDAKTEKKSAEEAGPKAPKGKGRSAHAYQFGNTIIVEDEDGEVIKKYSIPSVDKSEAKGNAPVRRGLVRMGTWFGKEEEGEPSQAGKKTHENEWLADDGLRFTLANDETVGKHGISHKGRRMTKQEFADQIRNLGPKARQSIVEDSDAPKRVKDAARDDAQQADKRERRASAAGSAHQTGAPHDDLESVSSGSDDEPDSEEGPGPNVAETLARIAAGTATGTAADERRKDLSPGTSSRERSPRSRRDSDDDGTERVPPSKLREAAGLALPQQALDLDDTGETPAERRRRLAALGEYSDSEDDVDSDAVSEGEDDHNNRKGPGKISFADGTNLEAGSTYDREGNGLGSSRMHSRRSRSRISWGGEKGRE
Protein: Small ribosomal subunit protein eS8A (40S ribosomal protein S8-A) (O14049)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS12A
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein eS7
- Elongation factor 3
- Large ribosomal subunit protein eL22
Sequence:
MGITRDSRHKRSATGAKRAQYRKKRKFELGRQPSNTRIGPKRIHEVRVRGGNKKFRALRLDSGNFSWGSEGVSKKTRIIQVAYHPSNNELVRTNTLTKSAIVQIDAAPFRVWYETHYGILMGSKGKKATSTPNPKSKHVQRKHSARLGDSKVDSALETQFAAGRLYAVVSSRPGQSGRCDGYILEGEELHFYLRRMAPKK
Protein: Uncharacterized protein YdaS (P76063)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Transcriptional regulator YdaT
- DNA-binding transcriptional repressor RacR
- Uncharacterized protein YdaU
- Uncharacterized protein YdaF
- Killing protein KilR
- Uncharacterized protein YdaV
Sequence:
MKKENYSFKQACAVVGGQSAMARLLGVSPPSVNQWIKGVRQLPAERCPAIERATRGEVLCEELRPDIDWSYLRRSACCSQNMSVKQLNDSNKSSFDHT
Protein: Siderophore exporter MmpL4 (P9WJV3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Part of an export system, which is required for biosynthesis and secretion of siderophores. Essential for normal replication during the active-growth phase of the murine tuberculosis model.
Subcellular location: Cell inner membrane {ECO:0000305|PubMed:23431276}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Siderophore export accessory protein MmpS4
- Siderophore export accessory protein MmpS5
- Putative phthiocerol dimycocerosate transporter LppX
- ESX-3 secretion system protein EccD3
- Mycobactin import ATP-binding/permease protein IrtA
Sequence:
MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFGLFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG
Protein: DNA ligase IV (Polydeoxyribonucleotide synthase [ATP] 4) (Q95YE6)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Ku domain-containing protein
- ATP-dependent DNA helicase II subunit 2
- Exonuclease 1
- DNA repair endonuclease XPF
- DNA polymerase theta
- ERCC1-like central domain-containing protein
- Protein hsr-9
- DNA replication ATP-dependent helicase/nuclease DNA2
- DNA mismatch repair protein
- DNA repair protein RAD51 homolog
Sequence:
MASDVIFDEVVDVFNKIRRTSNVKSKQATFQKNFESWKEKCSDPSDMFVIIRFFVSDYERFRKFDMGPTKLASFMAKTFHDVRADYVSTISKDASTAARQLAEKISEEYRTENDESTVVTVSELNEILDFLAAGPMDDGNKRDKMSKLVKRCSEDELEWIFNVILKNVESALGAPSNRILDWISPSACAIWDQTHDLKAVLKGKLVENKGTNELGETNDDDDEHLFKIWTPMLLQKQKRGDWYANIEKFGGQKFFLQTKFDGENVLLHKKGNEYRWFTRNNNDFSKEYGDSSMAIGKLSSRIHSFFNKECESAIFNCELMLWDKKTKKLCRHNDASTTSDAQVLSFRHVKPDDNQQLTVVLFDLLYLNGKPFFGAPLHQRLEMLKIAPLKKEREDTIFVAKHEEGSKKEDIQQFFEIAMANNEEGIVVKRTDSVYVKGQRSASNGWFKLKPSASKDCDLDLALVAVHPGAGRNGKTLYRFAAFDEKTQDYKLCLSCSYGLSDTVREAIRFEYGQLLEEAPEELTFYGKRPKNIARGDGGYIDFERWQVIKITSNGVRNGKLVDPVMREWRLDKPVEQVNTWEEFSDYATALQECKLGDNVDSDEEDSEDKKPDTLKVERITRKAIHQSAPVRLKRAKLESSLTGIEVAVLQGTSETIRRKCEEILKHFDATVVKGITPSTKLCIATAPKSTHPKTAQAIASNSCTVLKPAWLERCNKDDLIQAWLPSDVFHAIEGGFEIQE
Protein: Gap junction alpha-4 protein (Connexin-37) (Cx37) (Q03190)
Organism: Rattus norvegicus (Rat)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Interaction partners:
- Gap junction alpha-5 protein
- Gap junction alpha-1 protein
- Gap junction alpha-8 protein
- Gap junction gamma-1 protein
- Gap junction alpha-3 protein
- Gap junction beta-2 protein
- Gap junction beta-4 protein
- Gap junction protein
Sequence:
MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLIYLGHVIYLSRREERLRQKEGELRALPSKDPHVERALAAIEHQMAKISVAEDGRLRIRGALMGTYVISVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPHVVDCYVSRPTEKTIFIIFMLVVGVISLVLNLLELVHLLCRCVSREIKARRDHDTRPAQGSASDPYPEQVFFYLPMGEGPSSPPCPTYNGLSSTEQNWANLTTEERLTSTRPPPFVNAAPQGGQKSSSRPNSSASKKQYV
Protein: Uncharacterized membrane protein C70.04c (O74525)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Meiotic chromosome segregation protein C17A2.07c
- Uncharacterized membrane protein C1919.04
- Meiotic expression up-regulated protein 18
- Uncharacterized protein C18G6.13
- Uncharacterized protein C25B2.08
Sequence:
MKQNNKKPLPSKTKEISLETDWIDVIETMRETNESPKSQNPSEEATTVNELSCEAKPKLLFTPTKSSLSIGNFPYKEFDPVLKFPGIHYTYSRERLWGTCVILSTLFWSYYVLSNSELLEFEASEYSLLFILIIALDALLTVSLFGLFHHLMFLTTNYSYTINSTLDISKGFFINVLSTMVQALVTVTIAFTKFVTIDFPIYVFSSLFLYHPLSRSRQLPTKMQLDGSGERKTDSSLVHQNPPN
Protein: Cytolethal distending toxin (Q7DK12)
Organism: Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans)
Interaction partners:
Sequence:
MQWVKQLNVVFCTMLFSFSSYANLSDFKVATWNLQGSSAVNESKWNINVRQLLSGEQGADILMVQEAGSLPSSAVRTSRVIQHGGTPIEEYTWNLGTRSRPNMVYIYYSRLDVGANRVNLAIVSRRQADEAFIVHSDSSVLQSRPAVGIRIGTDVFFTVHALATGGSDAVSLIRNIFTTFTSSPSSPERRGYSWMVVGDFNRAPVNLEAALRQEPAVSENTIIIAPTEPTHRSGNILDYAILHDAHLPRREQARERIGASLMLNQLRSQITSDHFPVSFVHDR
Protein: Histone deacetylase 18 (EC 3.5.1.98) (Q8LRK8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (Probable). Histone deacetylases act via the formation of large multiprotein complexes (Probable). Required for appropriate cellular patterning in the root epidermis. Involved in the differentiation of hair and non-hair cells in the root epidermis. Is not directly involved in the regulation of the expression of pattern genes. Regulates the transcription of certain kinase genes, which are components of a positional information relay system, by changing their histone acetylation status.
Subcellular location: Nucleus {ECO:0000269|PubMed:23362208}. Cytoplasm {ECO:0000269|PubMed:23362208}.
Interaction partners:
- Histone deacetylase 17
- Histone deacetylase-related / HD-like protein
- Putative histone deacetylase 10
- NAD-dependent protein deacylase SRT2
- NAD-dependent protein deacetylase SRT1
- Putative high mobility group B protein 11
- High mobility group B protein 15
- High mobility group B protein 9
- High mobility group B protein 10
- Histone deacetylase 19
Sequence:
MLLKFEASSELRLVDPSVSLTVLRKIRLSHLPDMTMTSESSGKKCGEGDGKVAGKSQRKVGLVYDETMCKHDTPNGKVDVECPDRIRVIWEKLQLAGVTQRCVVLGGSKAEDKHLKLVHTKKHVNLVKSISTKKKDSRRNKIASQLDSIYLNGGSSEAAYLAAGSVVKVAEKVAEGELDCGFAIVRPPGHHAESDEAMGFCLFNNVAVAASFLLNERPDLDVKKILIVDWDIHHGNGTQKMFWKDSRVLIFSVHRHDHGSFYPFGDDGDFNMVGEGPGEGFNINVPWEQGGCGDADYLAVWNHILIPVTKEFKPDIILLSAGFDAAIGDPLGGCCVTPYGYSVMLKKLMEFAHGKIVLALEGGYNLESLGKSSLACVQVLLEDKQIHGSSETYPLESTRRVIQAVRERLCTYWPSLDASMASNENLKNPSAERNSADALLREVEELKSLMAARDGELEARRKELKAKNKELEANEKELEAGLMLIRAREDVICGLHAKIESLQQERDEAVAKAERIDKELQEDRARSQEFKEDTEFCLSTLRREKELAIMAKNKDLEAKEKELEARLMLVHAREDKIHAKIERLQQERDEAVAKAERIDKELQEDRSRSRVGNGSFAFSQEFYEDMDLDELEPLSPEFNEDMDSEELEPFQVIKKNMERSHKKFIKDMECIKFIASERARVL
Protein: Cilia- and flagella-associated protein 206 (Flagella-associated protein 206) (Q23H79)
Organism: Tetrahymena thermophila (strain SB210)
Function: May regulate cilium motility through its role in the assembly of the axonemal RS2 radial spoke.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:25540426}.
Interaction partners:
- Cilia- and flagella-associated protein 251
- TNFR-Cys domain-containing protein
Sequence:
MNQLEEIVKYVIYKCRENNHPVTETLAAFVTQTIYNPKTDRFYLEDKLTASQVDELKATVLQKLSQIDKPNMKTIQMQISYDSAYIESEIQRQERIKNQSIETGKLTDEVVSLEIKNAKDFEGLTVLFKKIFNFLLYKNKELMYDGTNKTGNQDSENQATQFNIEKEVAAGLESVIPRAALGPFVSLNPSEKVTQLVELSNLVIGIRLFNKWIQKGGIGLVPFQDLLEYEGRDLIERIRQEAFEVIENCDNYTIFFQNVGPGKIKISDEQFKQYKDELTFLRQYLSYILSIQEDVDISENSVDSNQTRYLKEIKDLETLLKQKSSAPKEQVYPKFATLAQAYIQLLEEKKLCLTRVKLFELLQEMRKGFKLTLPRNLILTAKNISQDPSNEEQVEIEYSEDCGIERLLPKNTPDFMQTPLDYLGFCLWSIVKRDGLLLPGKPALGVFRYKDKNCVFSDEKSINEFLSDPQQFIQGVINQCRKNPELIHLLRMDDSFKNVNLNIYVSGQEGGHQLSNKLMVDKGIETPLHFVEKRLDPNYCWNEWELRKKALQMANIRKRQTKACQTILSNFKVDSEAQTYLPKDNETNTGKTEWDIRKFAIEQAKKKGIIAGTDRAPYPIHPRNYITGLRDKDTN
Protein: Triggering receptor expressed on myeloid cells 2 (D3ZZ89)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- TYRO protein tyrosine kinase-binding protein
- High affinity immunoglobulin epsilon receptor subunit gamma
- Apolipoprotein E
- CD33 molecule
- Tyrosine-protein kinase SYK
- Clusterin
- Tyrosine-protein phosphatase non-receptor type substrate 1
- Triggering receptor expressed on myeloid cells 1
- CX3C chemokine receptor 1
- Plexin-A1
Sequence:
MEPLHVFVLLLVTELSQALNTTVLQGVAGQSLRVSCTYDALRHWGRRKAWCRQLAEEGPCQRVVSTHGVWLLAFLRKQNGSTVITDDTLAGTVTITLRNLQAGDAGLYQCQSLRGREAEVLQKVVVEVLEDPLDDQDAGDLWVPEESESFEGAQVEHSTSSQVSSCGSPLTYHLPPKEPIRKDLLPTHFHSSPPGLCPPEQASYSQHPLGCGQGQAEAGDTCGQWARLPRCWAPTSDPHWTQRYVREV
Protein: Ras-related protein Rab-24 (Rab-16) (P35290)
Organism: Mus musculus (Mouse)
Function: May be involved in autophagy-related processes.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:10660536, ECO:0000269|PubMed:12323076}. Membrane {ECO:0000269|PubMed:10660536, ECO:0000269|PubMed:12323076}; Lipid-anchor {ECO:0000305}. Note=Only about 20% is recovered in the particulate fraction. {ECO:0000269|PubMed:10660536}.
Interaction partners:
- Rab5 GDP/GTP exchange factor
- DCC-interacting protein 13-beta
- Geranylgeranyl transferase type-2 subunit alpha
- DCC-interacting protein 13-alpha
Sequence:
MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKGVDLSQKANPYFYSCCHH
Protein: Uncharacterized protein (Q38BW2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHPRVAKLYLDFMQLAPHATTFCGSTTAYRAAVQEGFSATRVVPGTPEFAHSLAKGRSVLGRLQDLITVRKYRAMMKRYSWSSYKNKQELVALLGETKAQSELLGLNNRDVYGYDDHYCHHAPSKPMGGEGDFSEK
Protein: TCF3 fusion partner homolog (Protein FB1) (Protein amida) (Q3U1J1)
Organism: Mus musculus (Mouse)
Function: Appears to promote apoptosis in a p53/TP53-independent manner.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- INO80 complex subunit E
- Nuclear factor related to kappa-B-binding protein
- Actin-related protein 8
- INO80 complex subunit C
- Actin-related protein 5
- Chromatin-remodeling ATPase INO80
- Ubiquitin carboxyl-terminal hydrolase isozyme L5
- Microspherule protein 1
- INO80 complex subunit D
- RuvB-like 1
Sequence:
MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGDSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRDSQFTIVLEDDGSQGTDVPTPGNAENEPPEKEGLSPSQRTTATLDPTSPAPGEGPSGRKRRRAPRVGASLTPELAPVQVGAEGWGQGVIKVEEDFGFEADEALDSSWVSREPDKLLPYPTLASPPFD
Protein: Erg4/erg24 family protein (Q55GJ9)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Probable lanosterol 14-alpha demethylase
- Putative methylsterol monooxygenase DDB_G0269788
- Probable 3-beta-hydroxysteroid-Delta
- Delta
- Protein erg2 homolog
- Putative methylsterol monooxygenase DDB_G0270946
- Sterol desaturase family protein
Sequence:
MLQGLPFSEDFSIFALPGMLTSWRAPTYESVLIFSSFLIFLGVGSHIVPGKYVKGQPLIYDQTKRLTYKINGLNLFFCLIGFFFFGSYYMKWFEPTLVYDHFGPIFTTVNIFATLLTITLFITGITSGRGKREGNLIHDLFLGVELNPRFAGLDLKFFALRPALMGWIMVNFSLAAQEYKVYGSLSTGMILYQIFTFIYAFDYFYFEECMLSTWDIIAENWGFMLIWGDLVWICFMFAVQPWFLLYNRIHLTPIQMIIISTIFAIGFAVFRISNSQKHQFKTNPKSLIWGKKPETIAGKLLVSGFWGILRKPNYLGDWIVAFSFSFPCLFNTPIVYLYPIYLVVLNSHRQWRDHQKCSKKYGELWKEYCRRVPYVVLPGLI
Protein: Probable small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG) (Q9N4G9)
Organism: Caenorhabditis elegans
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62308}. Nucleus {ECO:0000250|UniProtKB:P62308}.
Interaction partners:
- Probable small nuclear ribonucleoprotein Sm D2
- Probable small nuclear ribonucleoprotein-associated protein B
- Probable small nuclear ribonucleoprotein E
- Probable small nuclear ribonucleoprotein Sm D1
- Probable small nuclear ribonucleoprotein F
- Small nuclear ribonucleoprotein Sm D3
- U1 small nuclear ribonucleoprotein 70 kDa
- Probable U2 small nuclear ribonucleoprotein A'
- U6 snRNA-associated Sm-like protein LSm2
- Nuclear cap-binding protein subunit 2
Sequence:
MSKTHPPELKKYMDKEMDLKLNGNRRVSGILRGFDPFMNMVIDEAVEYQKDGGSVNLGMTVIRGNSVVIMEPKERIS
Protein: Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3P12) (P84109)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).
Subcellular location: Cell junction, adherens junction {ECO:0000269|PubMed:10085297}. Cell membrane {ECO:0000269|PubMed:10085297}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10085297}. Cell junction, focal adhesion {ECO:0000250}. Nucleus {ECO:0000250}. Nucleus matrix {ECO:0000250}. Note=Colocalized with PXN at focal adhesions during myogenic differentiation. Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. {ECO:0000250}.
Interaction partners:
- E3 ubiquitin-protein ligase CBL
- Vinculin
- Flotillin-1
- Flotillin-2
- Afadin
- Catenin beta-1
- Insulin receptor
- Catenin alpha-1
- Cadherin-1
- Coronin
Sequence:
LNRDDDSDLHSPRYSFSEDTKCDDGWFVGTSRRTK
Protein: C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (O88712)
Organism: Mus musculus (Mouse)
Function: Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q13363}. Nucleus {ECO:0000250|UniProtKB:Q13363}.
Interaction partners:
- C-terminal-binding protein 2
- DNA endonuclease RBBP8
- Histone deacetylase 1
- Zinc finger E-box-binding homeobox 1
- Histone deacetylase 2
- Zinc finger protein 217
- REST corepressor 2
- Transcription factor 7
- Krueppel-like factor 3
- Lymphoid enhancer-binding factor 1
Sequence:
MGSSHLLNKGLPLGVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGAAYSRYPPGVVSVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHTSDQL
Protein: Hephaestus, isoform L (A8JRI1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMSCPIPMPMPISSLHKSEFEPVNIGVKVRIDEQYIYKLNYLRGSDELLSQAAVMAPASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSGDKIVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQTTAPAMRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI
Protein: Transmembrane protein 236 (Q5W0B7)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MASGRLIKFVVFELLEFAAFSIPTLVITEQFATAYQGTRARSDNTHYWLIISCSIAYVALVTLLIWVPVKVILHKKRYIYRKIKGWRPVLMMCVVLTTLPCLTFSIAVTEVQKSINGSADVLPDMLPDLPVSLVLLSLIMVDIIEKLRIYPLRGSQKSSENGHIHSTSLQHIKTVTEQVRQSPENAASPQATNSTQVSQPSGAMTRSQESVFMGPQEPSCDSGILRMMSRRDVRAELFLWSFLLWSDTIEMVRVAGHPNVYKSSWLYPVYIFSFISLLRITFTPQNPLLNSLSVLLQDLPFVFVRLGLIIALGTITPVLGLCKNILVTLSYIYFNYLTRIRIFSAFEMSPF