wanglab/gogpt-training-data huggingface dataset:
Protein: RNA polymerase sigma factor FliA (RNA polymerase sigma factor for flagellar operon) (Sigma F) (Sigma-28) (P0A2E8)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. May regulate the expression of genes involved in virulence.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00962}.
Interaction partners:
- Protein FliZ
- Negative regulator of flagellin synthesis
- Flagellar hook-associated protein 1
- Flagellar basal body rod protein FlgB
- Flagellin
- Flagellar hook-associated protein 2
- Flagellar hook protein FlgE
- Flagellar basal-body rod protein FlgC
- Motility protein B
- Flagellar hook-associated protein 3
Sequence:
MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDLLQAGGIGLLNAVDRYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQAMGQLEQELGRNATETEVAERLGIPVAEYRQMLLDTNNSQLFSYDEWREEHGDSIELVTEEHQQENPLHQLLEGDLRQRVMDAIESLPEREQLVLTLYYQEELNLKEIGAVLEVGESRVSQLHSQAIKRLRTKLGKL
Protein: Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Renal high affinity glutamate transporter EAAC1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1) (Q95135)
Organism: Bos taurus (Bovine)
Function: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine (By similarity). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (By similarity). Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity). Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport. Negatively regulated by ARL6IP5 (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P51906}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P43003}. Apical cell membrane {ECO:0000250|UniProtKB:P43005}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P43003}. Synapse, synaptosome {ECO:0000250|UniProtKB:P51906}. Early endosome membrane {ECO:0000250|UniProtKB:P51906}. Late endosome membrane {ECO:0000250|UniProtKB:P51906}. Recycling endosome membrane {ECO:0000250|UniProtKB:P51906}.
Interaction partners:
- Amino acid transporter
- Sodium-coupled neutral amino acid symporter 2
- Solute carrier family 7 member 1
- Solute carrier family 7 member 8
- Transporter
- Sodium/glucose cotransporter 1
- Solute carrier family 38 member 1
- Solute carrier family 7 member 7
- Transporter
- Solute carrier family 7 member 5
Sequence:
MGKPARKGCDWKRFLRNNWLLLSTVVAVVLGIVIGVLVREYSKLSNLEKFYFSFPGEILMRMLKLVILPLIVSSMITGVATLDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVNEIDRTGNTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTTREEVELSEEPGTNSTEATVTAIMTTAISKNKTKEYKVVGMYSDGINVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQIIMCYMPIGILFLIAGKIIEVEDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGMAQALLTALMISSSSATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFTLESTALDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
Protein: Putrescine/agmatine-binding protein (Q9I0P5)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Binds putrescine and agmatine.
Subcellular location: Periplasm {ECO:0000305}.
Interaction partners:
- Putrescine transport system permease protein PotI
- Polyamine transport protein PotH
- Spermidine/putrescine import ATP-binding protein PotA
- Gamma-aminobutyric acid-binding protein
- Spermidine/putrescine transport system permease protein PotC
- Polyamine transport protein PotC
- Spermidine/putrescine transport system permease protein PotC
- Polyamine transport protein PotB
- Probable permease of ABC transporter
- Probable permease of ABC transporter
Sequence:
MKKVCALALSILTTIGATAADSAWAAQTSVHLYNWYDFIAPETPKAFQKETGTRVVLDTFDSAETAQGKLMVGRSGYDVVVITSNILPGLIKAGVLQELDRDRLPHWKNLDADILGKLQANDPGNRYAVPYLWGTTGIAYDVDKVRKLLGPDAPVDSWDLVFKEENISRLSQCGVATLDSSTELVSIALNYLGLPHNSQNPEDYQKAQELLLKVRPYIRYFDSSRVDTDLSNGNVCVVVGWQGTAYMAQVNNEQAGNGRHIAYSIPREGSLVWAENMVLLKDAPHPQQGYALIDYLLRPEVIARTSNYVGYPNGNQAALPLVERKLRENPAVYLSKETMATLFPLETLPLKVERIRTRVWSRVKTGS
Protein: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (Q94C79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKFVIPKLPFTLSLFLSLSFLIIFLFAFPTTFLRRPLSSSSSVTSVADEGIRIRHHGYSSYEAYIKHQLNKTQNPKLRKVWTTRDWDRKVRVFSTFFRRLSDRGLLSNQSKALSIGARVGQEVAALRLIGVEDSVGIDLVPRPPLVVKGDFHAQPFDEETFDFEFSNVFDHALYPEKFVGEIERTLKPGGVCVLHVSISGKTDKYSANDLLSVKPLVKLFKRSKVVEMRKIDGFGLDTEIVFRKNMN
Protein: Vomeronasal type-1 receptor (G5E8I3)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU364061}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU364061}.
Interaction partners:
- Vomeronasal 2, receptor 37
Sequence:
MFSLENVLYFQAGLGFIANMFLLVFYIFIILGHRPKLIDLISCQLTFVHILMILTGGNVMLADIFESLNVENDIKCKATLYTNRVMRGLSISITCLLSVIQAVTISPSTSMLAKFKHKLRKHMVNASFFYIWSFNFSLSSILIFYTGGFTNVSETKQMKITKSCSILPMNYIIRGMVVTVTTVRDVFLVGVMLITSAYMVIILFRHQRQCKHLHSINNLRTSPEKRATQTILLLVVFFVVLYWVDFILSSTSVTLWMYDPVILTVQKFLMNAYPIITPLLQISSDKRVINVMKTLQSKCH
Protein: Qa-SNARE protein (Q4Q5S9)
Organism: Leishmania major
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
Interaction partners:
- Uncharacterized protein
- Putative Qc-SNARE protein
- Putative R-SNARE protein
- Putative Qb-SNARE protein
- Putative SLY1 protein
- Putative SNARE protein
- Putative Qc-SNARE protein
- Putative Qc-SNARE protein
- Putative Qc-SNARE protein
- Putative SNAP protein
Sequence:
MRLTQLANCQSVFDDQTAELSELTQMVKSSLQRLHNDAATLEELKRRAVESQKGSIQAKGDARGMFGSSCNHLRTSEKHSDTVVETLRSRLARTGQQFRTTLQHQSKSLKNTANRRHMFTTADRPQTFESALFQDQEQHQQQQLLLSGMGNTQYYQQRADAVLEIEAAVQEVGELFNDFTRLVQEQEEVVLRIDTDVDTAVRHVNAGSNELMRYLTNLSSNRGLILKVFAMLFFFLMLFGSLVVR
Protein: HTH-type transcriptional regulator GlnR (P37582)
Organism: Bacillus subtilis (strain 168)
Function: Transcription repressor that represses many genes including ureABC and tnrA, during nitrogen excess. On the contrary of the MerR members, which require longer DNA sites for high-affinity binding, GlnR requires a DNA sequence of 17 nucleotides as minimal binding site.
Interaction partners:
- Glutamine synthetase
- Ammonium transporter
- Global transcriptional regulator CodY
Sequence:
MSDNIRRSMPLFPIGIVMQLTELSARQIRYYEENGLIFPARSEGNRRLFSFHDVDKLLEIKHLIEQGVNMAGIKQILAKAEAEPEQKQNEKTKKPMKHDLSDDELRQLLKNELMQAGRFQRGNTFRQGDMSRFFH
Protein: NADH-ubiquinone oxidoreductase chain 3 (EC 7.1.1.2) (NADH dehydrogenase subunit 3) (P05506)
Organism: Rattus norvegicus (Rat)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03898}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- Complex I intermediate-associated protein 30, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase 1 beta subcomplex subunit 6
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH-ubiquinone oxidoreductase chain 5
- NADH dehydrogenase 1 alpha subcomplex subunit 11
- NADH-ubiquinone oxidoreductase chain 4L
Sequence:
MNLLIIITINITLSFILISIAFWLPQMNLYSEKANPYECGFDPTSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTTNTTTMMATAFILVTILALGLSYEWTQKGLEWTE
Protein: Interferon 1ai3 (Interferon, alpha 1) (A0A7R8C3L7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MARPCAFLIALVVMMYWSTCSLGCALLQQQSLRNKRALTFLTQIRRFSPVSCLKDRKDFGFPLEKMDAQQIQKTQAIPILYELTQQVLNIFTSKDSSAAWDATLLDSFCNNLHQQLNDLKACLMQQSGVQEPPLTQEDSLLYVKEYFHRISVYLREKKHSPCAWEVVRAEVWRALSSSAKLLTRQSKEE
Protein: Calponin-3 (Calponin, acidic isoform) (Q15417)
Organism: Homo sapiens (Human)
Function: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Interaction partners:
- WD repeat-containing protein 90
Sequence:
MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYQDDYPRDYQYSDQGIDY
Protein: NAD kinase (EC 2.7.1.23) (ATP-dependent NAD kinase) (P65779)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00361}.
Interaction partners:
Sequence:
MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVSTPTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE
Protein: Probable chromosome-partitioning protein ParB (P9WIJ9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity).
Interaction partners:
- Probable chromosome partitioning protein ParA
- Ribosomal RNA small subunit methyltransferase G
- Uncharacterized protein Rv1708
- Possible SOJ/para-related protein
- DNA translocase FtsK
- Conserved protein similar to jag protein
- Membrane protein insertase YidC
- Cell division protein FtsZ
Sequence:
MTQPSRRKGGLGRGLAALIPTGPADGESGPPTLGPRMGSATADVVIGGPVPDTSVMGAIYREIPPSAIEANPRQPRQVFDEEALAELVHSIREFGLLQPIVVRSLAGSQTGVRYQIVMGERRWRAAQEAGLATIPAIVRETGDDNLLRDALLENIHRVQLNPLEEAAAYQQLLDEFGVTHDELAARIGRSRPLITNMIRLLKLPIPVQRRVAAGVLSAGHARALLSLEAGPEAQEELASRIVAEGLSVRATEETVTLANHEANRQAHHSDATTPAPPRRKPIQMPGLQDVAERLSTTFDTRVTVSLGKRKGKIVVEFGSVDDLARIVGLMTTDGRDKGLHRDAL
Protein: Transmembrane emp24 domain-containing protein 9 (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (Q99KF1)
Organism: Mus musculus (Mouse)
Function: Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Cycles between compartments of the early secretatory pathway. {ECO:0000250}.
Interaction partners:
- Transmembrane emp24 domain-containing protein 10
- Transmembrane emp24 domain-containing protein 2
- Transmembrane emp24 domain-containing protein 5
- Transmembrane emp24 domain-containing protein 3
- Surfeit locus protein 4
- Transmembrane emp24 domain-containing protein 7
- Vesicle-trafficking protein SEC22b
- Transmembrane emp24 domain-containing protein 1
- Syntaxin-5
Sequence:
MAAVRGVRVVGSSPGLLLGRGMRAFLLLLWLAARGSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV
Protein: DNA polymerase delta small subunit (EC 2.7.7.7) (Hydroxyurea-sensitive protein 2) (P46957)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA polymerase delta (DNA polymerase III) participates in chromosomal DNA replication. It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork. It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication. It is also involved in DNA synthesis during DNA repair.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA polymerase zeta processivity subunit
- DNA polymerase delta catalytic subunit
- DNA polymerase zeta catalytic subunit
- DNA polymerase delta subunit 3
- Proliferating cell nuclear antigen
- DNA polymerase epsilon catalytic subunit A
- DNA polymerase alpha catalytic subunit A
- DNA polymerase epsilon subunit B
- DNA polymerase alpha subunit B
- DNA primase large subunit
Sequence:
MDALLTKFNEDRSLQDENLSQPRTRVRIVDDNLYNKSNPFQLCYKKRDYGSQYYHIYQYRLKTFRERVLKECDKRWDAGFTLNGQLVLKKDKVLDIQGNQPCWCVGSIYCEMKYKPNVLDEVINDTYGAPDLTKSYTDKEGGSDEIMLEDESGRVLLVGDFIRSTPFITGVVVGILGMEAEAGTFQVLDICYPTPLPQNPFPAPIATCPTRGKIALVSGLNLNNTSPDRLLRLEILREFLMGRINNKIDDISLIGRLLICGNSVDFDIKSVNKDELMISLTEFSKFLHNILPSISVDIMPGTNDPSDKSLPQQPFHKSLFDKSLESYFNGSNKEILNLVTNPYEFSYNGVDVLAVSGKNINDICKYVIPSNDNGESENKVEEGESNDFKDDIEHRLDLMECTMKWQNIAPTAPDTLWCYPYTDKDPFVLDKWPHVYIVANQPYFGTRVVEIGGKNIKIISVPEFSSTGMIILLDLETLEAETVKIDI
Protein: Zinc finger protein 25 (Zinc finger protein KOX19) (P17030)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MNKFQGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNAVFKLKQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRNGELTKHQKTHTTEKACECKECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQKIHTRDKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTGEKPFECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPYKCKECGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNKCGKTFYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKSFSQKSHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK
Protein: Factor VIII (Q7TN96)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MRAARGLCFFLSLCALCSCATRKYYLGAVELPWDYVSGGASGAQRSDSRFPPGTPAPSAHVVHTKTVFVEYMDRFFHTAKPRPLWMGLLGPTIWTEVHDTVVITLKNMASHPVSLHAVGMSFWKASEGAAYDDHSSPAEKDDDKVLPGESHTYAWQVLGESGPMASDPPCLTYAYLSHVDLVRDLNSGLVGALLVCKEGRLSAERTRMPPHFVLLFAVFDEGRSWHAATRDPASTEAQPTVHTVNGYTNRTLPGLTGCRGTSVYWHVMAVGTTPDIHSILLEGHTFSVRSHRQASLEISPMTLLTAQTWLMDLGRFLLFCHISSHRHGGMEAYVQVDNCPEAPQGQGKRDEDTEDYDDLDSEMDVFTWDPDAAPFVQVRSAAKRHPKTWVHYIAAEEGDWDYAPAAATLEDGSLRNRYLGRGPGRIGSKYKKVRFVAYTDGTFHTREATPREAGLLGPLLYGEVGDSLLIVFKNRASRAYNIHPHGIRDVGAVHAGRLPRGVKHVKDLPIRPGETFKYRWTLTAEDGPARSDARCVTRYYASAVDPERDLASGLIGPLLICCKESVDQRGNQMMSDERNVILFSVFDENRSWYISENMRRFLPDEAHVQLQDPEFEASNLMHSINGYVFDGLELRVCLHEVAAWHVLSVGAQTDFLSVFFSGHTFRHRAVYADTLTVFPHSGVTVFMSMDNPGVWVLGCHNPDFRESGMTALLKVSSCDEGVSDYYGETYEGVLAPLANDNAVDPRSFSQNSNHLHSRKKKSNTPMRFPLSHPTQHGSFWSDSQGDVHDAVHRAHSPAAAHSNEGPAEAAQLEPKPHPGEKMALPPSWLRAKRSLVTTMEAKRKKLDLQVQVSGLPDDRTTAVVAPDDPMAACKKAGSSGFPDESSPAALGKKMYPRIRPHGPLSIIEGNRDSNSSDSTLMYRLGSPPGDATSWTENRRGLGEKRSHRVAFLARGNTLLSDVDEKSHAPGPTSVGNSTAAVQDTILEICSEILEVTPPIHDRILSDKSATYLRPHRTPDRITSTERKDIRHEKDGDLVPQDADDTSAPFSEAPFLSESTDWLKEANGDNSAKPEQEPSPEQLVYLMYIKCMENQSFSSEKNKMIAGQGGFTKNTGLEDTVFPRKTSVFLTTVAKRQESGRHNQENIPQAVTEKEAPIEEKGALPQVHIATGSKNFPRDMFVLGTGQNINLHEETYVPVHKNVPWTRNPTDTRQIPMVHFFKKRKEEETNSGGLVNKTRETVRNYPSQKNSVARRREQASGRIKASARWLPDVNRSIQSLLKQIDHRKERKKFIIESRSADSSGTKSPTQTNHSPSHVVKMSAFPPRDIRRIESRDSSQVWVSSYAYDFETGSSRIRESSPFLNETETDNPSLAVPPRERFVRRGRFASPEKVNTHSAPCDKPENVVSSEPVSPGEAVTVALPPHVSTQEEEPLPAGSSCERRGHVDLFLEISLQRTRGPVERSRGRRSGGDTEGHTENPGKTPSPLPQMPKDQRGSEAGYPKICRWRDGTVLPPRPHNLSLGAKKKPNLPRREATRVEQGEAPSLVSPEPLVLRRRPREASTLLPGGEMREDDGDGVTAEYDDDDDVMAEYDDDAVTVDTPEDFDIYGEEAGQGPRGFQQKTRHYFIAAVEELWDYGVRVSPGALGDRAWSGDAARFRKVVFREFTDGSFTQRVHRGELDAHLGLLGPYIRAEVEDNIVVTFRNQASRPYSFYSSLVSYPEADGGAAPRSNFVRPNETKTYFWRVRPHMAPTDGEFDCKAWAYFSDVDLERDLHSGLIGPLLVCHASTLHPSHARPLAVQEFALLFAVFDETKSWYCAENLDRKCRPPRGTPAGDPAWREEYRFHAVNGYVADALLGLVMAEGRRTRWHLLSMGDPGHAQSVHFSAHSVTVRDGGEHRTAVCNLYPGVFTTVEMLPSRAGIWRVESLVGEHLRAGMSALFLVYSTRCQVPLGMASGYIRDSQITASGYHGLWTPQLARLHNAGSVNAWSAKEPFAWIKVDLLAPMILHGIETQGARHRLSSLYVSQFIIMYSLDGKQWLSYRGNSTGSLMVFFGNVDASTVRHNRFDPPIVARYIRVHPTHASIRTALRMELLGCDLNSCSAPLGMESGWISDTQVTASSHLSTTFSAWPPALARLHLRGGANAWRPQVNDPTQWLQVDLQRTVKVTGVVTQGARSLLTAMFVKKFLVSTSQDGRHWTHVLQDGKVKVFQGNRDASTPMVNSLHPPRFTRYLRIHPQVWERQIALRLEILGCEAQQLD
Protein: Sequence-specific DNA binding transcription factor (Q8RWY5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ethylene-responsive transcription factor RAP2-12
- LOB domain-containing protein 41
- Plant cysteine oxidase 1
- Ethylene-responsive transcription factor RAP2-2
- Pentatricopeptide repeat-containing protein At2g20710
- Hydroxyproline-rich glycoprotein family protein
- Pyruvate decarboxylase 1
- Plant cysteine oxidase 2
- E3 ubiquitin-protein ligase PRT6
- At5g02550
Sequence:
MESNVMFSGFSPRMLSLEMPQNPPNPQNSIQFQHPHPYTTSGDQQTQPPIKSLYPYASKPKQMSPISGGGCDDEDRGSGSGSGCNPEDSAGTDGKRKLSQWHRMKWTDTMVRLLIMAVFYIGDEAGLNDPVDAKKKTGGGGGGGGGGGMLQKKGKWKSVSRAMVEKGFSVSPQQCEDKFNDLNKRYKRVNDILGKGIACRVVENQGLLESMDHLTPKLKDEVKKLLNSKHLFFREMCAYHNSCGHLGGHDQQPPQQNPISIPIPSQQQNCFHAAEAGKMARIAERVEVEEEVESDMAEDSESEMEESEEEETRKKRRISTAVKRLREEAASVVEDVGKSVWEKKEWIRRKMLEIEEKKIGYEWEGVEMEKQRVKWMRYRSKKEREMEKAKLDNQRRRLETERMILMLRRSEIELNELQSSGTRVDPSSAKG
Protein: Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB) (Q08289)
Organism: Homo sapiens (Human)
Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Subcellular location: Cell membrane, sarcolemma {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- Voltage-dependent L-type calcium channel subunit alpha-1C
- Voltage-dependent L-type calcium channel subunit alpha-1D
- Voltage-dependent calcium channel subunit alpha-2/delta-1
- Voltage-dependent calcium channel subunit alpha-2/delta-2
- Voltage-dependent L-type calcium channel subunit alpha-1S
- Voltage-dependent L-type calcium channel subunit alpha-1F
- Voltage-dependent L-type calcium channel subunit beta-3
- Voltage-dependent P/Q-type calcium channel subunit alpha-1A
- Voltage-dependent calcium channel subunit alpha-2/delta-4
- Voltage-dependent L-type calcium channel subunit beta-1
Sequence:
MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Protein: E2F transcription factor 6, isoform CRA_d (E2F6 splice variant c) (E2F6 splice variant d) (E2F6 splice variant e) (cDNA FLJ38878 fis, clone MESAN2015365, highly similar to TRANSCRIPTION FACTOR E2F6) (Q53YM3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU003796}.
Interaction partners:
Sequence:
MDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEVSN
Protein: Anon1A3 (Q9U4Q6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
GVENLPSVAEAKQNHVDEVKPISEEPGNSSEEVPKAEEPLKSSGETSENGAATETAAAPKEPASVMDVDEDETLVENTPSANKEKALDDEKEPEQKSEEHAAAVLESKEQNEPAKEPTPEPMEVDGSSKGSSDTAQVDTPAIENVSAAPETEAAAKTTESSNDVVEVATEGKETVLEVPAAEPKEAESTVESAEELTETSTVVVTEPKEAASSEEEPSKVVDSAEPKEAESNTDKSATPVPIDVSTAPASNDVSKPLEIDTTLVKTADSPAKEPQEICEVKKAEINVNGEPKIVNSSAEVGENAAPKVCN
Protein: Tyrosine-protein kinase Srms (EC 2.7.10.2) (Q9H3Y6)
Organism: Homo sapiens (Human)
Function: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation of KHDRBS1 is EGF-dependent.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23822091, ECO:0000269|PubMed:29496907}. Note=Localizes to punctate cytoplasmic structures. {ECO:0000269|PubMed:23822091, ECO:0000269|PubMed:29496907}.
Interaction partners:
- Protein-tyrosine kinase 6
Sequence:
MEPFLRRRLAFLSFFWDKIWPAGGEPDHGTPGSLDPNTDPVPTLPAEPCSPFPQLFLALYDFTARCGGELSVRRGDRLCALEEGGGYIFARRLSGQPSAGLVPITHVAKASPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSLYLQKGRLFPGLEELLTYYKANWKLIQNPLLQPCMPQKAPRQDVWERPHSEFALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKLHAIHRCHP
Protein: Uncharacterized protein (Q582P3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRETAIMNNRLVLPASASTDAENGSVHVRGGTRCCGPCCHSDQKRGRSVWTKPTLEADDTADSDACEDVVKRSERLLELLRVRKIQCDSAVDTSSMIYDVEAEMSPLAASGTRMCRAVFSQSSALVPLSSIAGDKDLVEFDVSGEEKTNPVPVSSRSLLKVAITCTDAETQTLPAPVGYRVENPIMTKPDWFVLRLCELDALLHIFFS