wanglab/gogpt-training-data huggingface dataset:
Protein: Chitinase 6, isoform H (EC 3.2.1.-, EC 3.2.1.14) (A8JUP3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLPFRRGAAWQTLFLLCALAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYLCTHLVYAFGGFTKDNQMKPFDKYQDIEQGGYAKFTGLKTYNKQLKTMIAIGGWNEASSRFSPLVASNERRQQFIKNILKFLRQNHFDGIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREAEKTGRTRLLLTMAVPAGIEYIDKGYDVPKLNKYLDWFNVLTYDFHSSHEPSVNHHAPLYSLEEDSEYNYDAELNIDYSIKYYLKAGADRDKLVLGIPTYGRSYTLINEESTELGAPAEGPGEQGDATREKGYLAYYEICQTLKDDPEWTVVQPNANVMGPYAYRRNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRGTCNGKPYPLIEAAKEAMVEALGLGINEVAKPSGPQKPSRSRSRDNASNRNRLNGKTEAPLSSRRPSATRRPAVSSTQAPPPSTTFKLTEAEGSSLYIGGRASTTPPPPTTPDPGSDFKCEEEGFFQHPRDCKKYYWCLDSGPSGLGIVAHMFTCPSGLYFNPAADSCDFARNVPCKTKKSTTAAPVTSTTPATTTVRSNRVTAAPTSRPVYPRTTTTTSTTTTTTTTPSTVDEDLEYEEDTDELSPSKSTDAEEDPQVIKELIDLIRKVGGVEQLEKHLLRNKDGSITLKENSATGAATTPSTISKSLYDRVLSRPGTLNSFSRNRFKISEASETSTEPTTSSSSSRGSSTLTSNTNSKYSSVLRGNSRQGPQNEGIEKLAEFDGFLKERKQYVTINRHRSASQGDEEEHADQQEEEENLAEVETTTRRPLSSITPSYTSLRRSRPTTVAPPAEESHEEAEQQTQTQVKSYATLSRTRGRTTSSPEVTEAAPSSTTNRYKYFERTRPTKSATAEDSEDPTEDEEEEYEDEQKDIVTNRYQLSRTRGSTTTNTNPTTTQQPQTTSTARRLAFGGRQRAQVTKLTLVDEQTEETETKGDSREEEKEEEEEEDSNATTTTTTTTTSRPTPKRIRVLKFRRPLNSNSNSTINVDSTTNSATDTNPDTTTATPTTAGQSTTSNSNNNNNNTTSTTGNKRFRKIVRKLRPVDSSTAASVDNSDETTRKPFVPSHTRFADQDNDLVNLRQRIKEQQARGEPQDGVISNRFKTLGQKDDQDVSELQKLRDKVKAEQARGEGEQGVINDRLKKLLAEKGSSISSQREESSTDDDSSSVSSARPFFKRKLVARRPYTPPSASGGTTKAPLTFSTSRPTAKFVRRKNGRFDPFNSSVRNRGEGFVRSDPRGSRLPGTDRFKSQGNSEDDDEVEERHEQPLQNQFATTLRRPFVPKTRPVLDKSKPEQEDGAEESEEEDEEEDSEEEGDEEEDEEEEDVKPGGEEDNAQEDNKPKFNSPYKPKDNRAPPGSRPTFGTTGSGSPPTASGNVPYNPRNRPSNSANGNSTPSNRFGTTKRPRVVNRPPGVASPNLTLKPVASDYERTTPLTPLKPAPFIPSNNRSYERKYSGPSTEAAETASENSLIEDLNIDALNARNKKIFDKHSKKHPALKPKVVKVESETGLEVEAGTEVAVEDETTEEQQQEQGFVTTTPSTPPSPAPPSTQSDTATTTDTPPETETETETETETETETENVTEIETATNANEATSINSQDQTISSTTQAPPPATTLLHVFTLLEGEGQEEEPTTRKPTVRLYPTIQTEVVPKHKLIEINRIVEINSKQAKAAQRKSKANHDFSTLMVESLPHVEQLGEISVVKYVHLVDGSDIQINDGHSTVADYTPTEPTSAAERPVSLPVRNSLPETEGADTDRSGKSLVPEVLTAALETSTISLEGLFDSARKGKQLSSNTIIGETEESTTIGSSSSLASETGETTTPAPTYVRPIVPLLRPESNESSPLVISIANLDQVILSKVQKSLAENSQTTVAPEAASDSNSAFSVRQPLVVQAPISNGAQEIDQDTLNTQDQTINGAISVKTNPIIQTTTNRPNDDQVAEETTIFSIETATEPELNTQTTIPKTEANSETVTAMPIGAVIMGQFGLNTQSTTAVDNDNQLNAQTTSTISSGAVSSVAIGGNTQTANADNARQENTQSTGTITSEISSGAISSDNHNHIGTQTTATIDSSSETTPTQISTTISSGAISGHIDGSINLNTQTNTTISTNNTTTSTTDVGSKVSEAVSFSSETHVVHRKKMGRKGRGRRLRNRKTTTTTTTTETPTTTEATFDDTTTVVPE
Protein: Immunoglobulin-binding protein EibD (Trimeric autotransporter adhesin EibD) (TAA EibD) (Type 5 secretion system autotransporter EibD) (Q9MCI8)
Organism: Escherichia coli
Function: Binds (in a non-immune fashion) to the Fc portion of human IgA and IgG; binding occurs on the cell surface. Confers the ability to survive exposure to human serum exposure. Binds to the Fc portion of human IgG, IgA and to whole mouse antibodies also via Fc. Upon overexpression cells acquire an extra cell surface layer that forms a zipper-like contact between cells; cells autoagglutinate and form biofilm more readily, suggesting it may play a role in defense against a host.
Subcellular location: Cell surface {ECO:0000269|PubMed:22155776, ECO:0000305|PubMed:10722621, ECO:0000305|PubMed:19303642, ECO:0000305|PubMed:21742268}. Cell outer membrane {ECO:0000269|PubMed:22155776, ECO:0000305|PubMed:10722621, ECO:0000305|PubMed:21742268}; Multi-pass membrane protein {ECO:0000305|PubMed:22155776}. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface. {ECO:0000269|PubMed:22155776, ECO:0000305|PubMed:10722621, ECO:0000305|PubMed:19303642, ECO:0000305|PubMed:21742268}.
Interaction partners:
Sequence:
MSKKFTMTLLSSSLAGLLVMSGGVSAQNGTYSVLQDDSQKSGPVKYGSTYEVVKTVDNGNFRYEVKEKKNDKRTLFKFDSEGNVTVKGKGITHTLHDPALKDFARTAEGKKNEQNGNTPPHKLTDSAVRGVYNKVYGLEKTEITGFSVEDGENGKVSLGSDAKASGEFSVAVGNGARATEKASTAVGSWAAADGKQSTALGVGTYAYANASTALGSVAFVDNTATYGTAAGNRAKVDKDATEGTALGAKATVTNKNSVALGANSVTTRDNEVYIGYKTGTESDKTYGTRVLGGLSDGTRNSDAATVGQLNRKVGGVYDDVKARITVESEKQKKYTDQKTSEVNEKVEARTTVGVDSDGKLTRAEGATKTIAVNDGLVALSGRTDRIDYAVGAIDGRVTRNTQSIEKNSKAIAANTRTLQQHSARLDSQQRQINENHKEMKRAAAQSAALTGLFQPYSVGKFNATAAVGGYSDQQALAVGVGYRFNEQTAAKAGVAFSDGDASWNVGVNFEF
Protein: COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2) (P24468)
Organism: Homo sapiens (Human)
Function: Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development.
Subcellular location: Nucleus.
Interaction partners:
- BCL11 transcription factor A
- B-cell lymphoma/leukemia 11B
- Arginine-glutamic acid dipeptide repeats protein
- Histone acetyltransferase p300
- Transcription factor SOX-18
- Zinc finger protein ZFPM2
- Nuclear receptor corepressor 1
- Peroxisome proliferator-activated receptor gamma
- Myocyte-specific enhancer factor 2C
- Prospero homeobox protein 1
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Protein: Glycine betaine transporter OpuD (P54417)
Organism: Bacillus subtilis (strain 168)
Function: High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Choline-binding protein
- Choline transport system permease protein OpuBB
- Betaine aldehyde dehydrogenase
- High-affinity proline transporter PutP
- Osmoregulated proline transporter OpuE
- Glycine betaine-binding protein OpuAC
- Choline transport ATP-binding protein OpuBA
- Choline dehydrogenase
- Glycine betaine/carnitine/choline transport ATP-binding protein OpuCA
- Na
Sequence:
MLKHISSVFWIVIAITAAAVLWGVISPDSLQNVSQSAQAFITDSFGWYYLLVVSLFVGFCLFLIFSPIGKIKLGKPDEKPEFGLLSWFAMLFSAGMGIGLVFYGAAEPISHYAISSPSGETETPQAFRDALRYTFFHWGLHAWAIYAIVALCIAYFQFRKGAPGLISSTLSPILGDKVNGPIGKAIDCIAVFATVVGVSTSLGLGATQINGGLNYLFGIPNAFIVQLVLIIIVTVLFLLSAWSGLGKGIKYLSNTNMVLAGLLMLFMLVVGPTVLIMNSFTDSIGQYIQNIVQMSFRLTPNDPEKREWINSWTIFYWAWWISWSPFVGIFIARVSRGRTIREFLIGVLVTPCILTFLWFSIFGVSAMDLQQKGAFNVAKLSTETMLFGTLDHYPLTMVTSILALILIAVFFITSADSATFVLGMQTSYGSLNPANSVKLSWGIIQSAMAAVLLYSGGLAALQNTAILAALPFSIVILLMIASLYQSLSKERREIKKAEKLDKPRSPRVKKAY
Protein: Transcriptional activator protein LuxR (P35327)
Organism: Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
Function: Transcriptional activator of the bioluminescence operon. Binds to the OHHL autoinducer.
Interaction partners:
- Acyl-homoserine-lactone synthase
- Acyl-CoA reductase
- Alkanal monooxygenase
- S-ribosylhomocysteine lyase
- Quorum sensing transcriptional regulator LitR
- Acyl transferase
- Alkanal monooxygenase
- acyl-homoserine-lactone synthase
- DNA-binding response regulator in two-component regulatory system with GacS
- histidine kinase
Sequence:
MNIKNINANEKIIDKIKTCNNNKDINQCLSEIAKIIHCEYYLFAIIYPHSIIKPDVSIIDNYPEKWRKYYDDAGLLEYDPVVDYSKSHHSPINWNVFEKKTIKKESPNVIKEAQESGLITGFSFPIHTASNGFGMLSFAHSDKDIYTDSLFLHASTNVPLMLPSLVDNYQKINTTRKKSDSILTKREKECLAWASEGKSTWDISKILGCSERTVTFHLTNTQMKLNTTNRCQSISKAILTGAINCPYLKN
Protein: Fibroblast growth factor (FGF) (O42407)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MCKWILTNGASAFSHLPCCCLLLLFLVSSVPVTCHDLGQDMLSPEATNSSSSSSSSFPSSFSSPSSAGRHVRSYNHLQGDVRKRKLYSYNKYFLKIEKNGKVSGTKKENCPFSILEITSVEIGVVAVKSIKSNYYLAMNKKGKVYGSKEFNSDCKLKERIEENGYNTYASLNWKHNGRQMFVALNGRGATKRGQKTRRKNTSAHFLPMVVMS
Protein: Myocardin related transcription factor A (F1LVR8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
LTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEALIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLESRASDLLPSATSISPTQVLSQLPMAPDPGETLFLAEQPPLPPPPLLPPSLTSGSIVPTAKPAPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPPKPSGETPGSSAPTPSRSLSTSSSSSSGTPGPGGLARQNSTALAGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTSVLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNGMVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDAFGEMVTSPLTQLTLQASPLQIVKEEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASSPVKRESSFSSCQLSCQPQGAARAFGPGLVVPTTNHGDAQAPAPESPPVVVKQEAGPPEPDLAPASQLLLGSQGTSFLKKVSPPTLVTDSTGTHLILTVTNKSADGPGLPTGSPQQPLSQPGSPAPGPPAQMDLEHPPQPSFATPTSLLKKEPPGYEETVTQQPKQQENGSSSQHMDDLFDILIQSGEISADFKEPPSLPGKEKSPPAEAYGPPLTPQPSPLSELPQAAPPPGSPTLPGRLEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSPMDTSELHFAPEPSSGMGLDLAVGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSMDFLDGHDLQLHWDSCL
Protein: U3 small nucleolar RNA-associated protein 15 homolog (Q7ZW33)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Nucleolar protein 58
- PWP2 small subunit processome component.
- UTP6 small subunit processome component.
- Cirrhosis, autosomal recessive 1A
- UTP18 small subunit processome component.
- HEAT repeat-containing protein 1
- WD repeat-containing protein 75
- WD repeat domain 43.
- Nucleolar complex protein 4 homolog
- WD repeat domain 46.
Sequence:
MASFKPTKVLSYPKLGEKVTEETLYWKNYKPPVQIKEFGAVSKIDFSPLPPHNYAVTASTRVHIYGLHSQEPIRNFTRFHDTAYGGSFRGDGKLLVAGSEEGLIRLFDIGGRVSLRQFKGHSKAVHATSFLSDGFRVLSGSDDLTCRVWDVASAVELSSITEHTDYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRSGNSVMTMQHGQPVECVLLYPSEALLVSTGGRYVKVWDLLKGGQQLVSLKNHHKTVTCACLSSSNKLLTASLDRHVKVYNSSYKVVHNFDCASSILSLAVAPDDEAVAVGMTNGVLSIRHRKHKEEKEALTGRRKRGPSYRFFVKGKNFVPRQDDFLVSKPVRQHLQKYDKQLKRFEVSKALDTALETWTRTTKPEVTVAVIMELNRRGTLKNALAGRDEVSLTKILNFLLKHITDPRFSRPLLTVGDIVLDLYQQVIPQSPVVERLLQRLYEILGREAELQQELLQVLGILDTLFASLMPRKEVASFGAAAAAQESQLQAA
Protein: AT3g17900/MEB5_12 (Heat-inducible transcription repressor) (Q9ASZ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transport protein particle
- Diacylglycerol O-acyltransferase 2
Sequence:
MNFLLRSASSATHRPPVIEPPATPPQPPPETAKPGVTLEGLIAEEHFPQYPSVDEDLDRVGDGSGDLDGNGESNAKSGGSGMERFSDVSEEQGWIAIPYKEIPDNWSESVDIHSLRSLDRSFVFPGEQIQILACLSESKGDTEIITPFKVAEVMSRTGQRKVSDKQNGDMSDGASTPSGDGEMSPDAQFATQNGDSPCKESLDSQKDLSDGESILRMEDHKRRTEDLLSRFQKSHFFVRIAESGEPLWSKKSSLVADTEMDEERKRTKSRPCVSAFVDRGDFDPNVSGGVARSKAKCCALPNGDIVVSLQVYIVDCPKEPIIEILQFEKHQDQDQNPENDKDPYGNLLKWLIPLDNTISQQPRSLPPPITPSPSISSTAHKPAISSTSGSQLFSFGHFRSYSMSALPPNTAPVTGPIKTQSSKPSFDIEDWDSYSGQTVRNGQKSGTEELLSFRGVALERDRFSVRCGLEGICIPGRRWRRKLEIIQPIEINSFAADCNTDDLLCVQIKNVAPTHAPDIVIYIDAITIVFEEAGKNASPSSVPIACIEAGNEHSLPNLTLRKGEEHSFIVKPAFSVGSNLKPSAARNKLKSSSLSLPTVNFERKGSGLSGDQYAVMVSCRCNYTESRLFFKQRTKWRPRVSRDLMISVASEMSGEPCGPHGRASQLPVQILTLQASNLTSEDLSLTVLAPASFTSPPTVVSLNSTPTTPISPFLGFSDFTERVQNEKRNTTVRKQQSLPPIPLETRTENNTNGESSNPSDVVPKSGLGCTHLWLQSRVPLGCVPSKSTATIKLELLPLTDGIITLDTLQIHAKEKGRRYIPEQSLKINATSSISSGIF
Protein: Serine protease 32 (E9Q409)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MELALPAILFTFFPGVLLGSEVLPTDSDSPSTTTGRRSIDLDSVCGRPRTSGRIVSGQDAQLGRWPWQVSVRENGAHVCGGSLIAEDWVLTAAHCFNQGQSLSIYTVLLGTISSYPEDNEPKELRAVAQFIKHPSYSADEHSSGDIALVQLASPISFNDYMLPVCLPKPGDPLDPGTMCWVTGWGHIGTNQPLPPPFTLQELQVPLIDAETCNTYYQENSIPGTEPVILEGMLCAGFQEGKKDACNGDSGGPLVCDINDVWIQAGVVSWGSDCALFKRPGVYTNVSVYISWIQNTMWNLPMEGRGFSPSLSGTPLLGLLLFLTSLSSAFFLLGP
Protein: Guanylate cyclase 2G (EC 4.6.1.2) (Guanylyl cyclase receptor G) (GC-G) (Kinase-like domain-containing soluble guanylyl cyclase) (ksGC) (P55205)
Organism: Rattus norvegicus (Rat)
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000250|UniProtKB:Q6TL19}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000305}.
Interaction partners:
- Inosine triphosphate pyrophosphatase
- Phosphodiesterase
- cGMP-specific 3',5'-cyclic phosphodiesterase
- High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
- Molybdenum cofactor biosynthesis protein 1
- GTP cyclohydrolase 1
- cGMP-dependent 3',5'-cyclic phosphodiesterase
- Phosphodiesterase
- Phosphodiesterase
- Phosphodiesterase
Sequence:
MASRARSEPPLEHRFYGGAESHAGHSSLVLTLFVVMLMTCLEAAKLTVGFHAPWNISHPFSVQRLGAGLQIAVDKLNSEPVGPGNLSWEFTYTNATCNAKESLAAFIDQVQREHISVLIGPACPEAAEVIGLLASEWDIPLFDFVGQMTALEDHFWCDTCVTLVPPKQEIGTVLRESLQYLGWEYIGVFGGSSAGSSWGEVNELWKAVEDELQLHFTITARVRYSSGHSDLLQEGLRSMSSVARVIILICSSEDAKHILQAAEDLGLNSGEFVFLLLQQLEDSFWKEVLAEDKVTRFPKVYESVFLIAPSTYGGSAGDDDFRKQVYQRLRRPPFQSSISSEDQVSPYSAYLHDALLLYAQTVEEMMKAEKDFRDGRQLISTLRADQVTLQGITGPVLLDAQGKRHMDYSVYALQKSGNGSRFLPFLHYDSFQKVIRPWRDDLNASGPHGSHPEYKPDCGFHEDLCRTKPPTGAGMTASVTAVIPTVTLLVVASAAAITGLMLWRLRGKVQNHPGDTWWQIHYDSITLLPQHKPSHRGTPMSRCNVSNASTVKISADCGSFAKTHQDEELFYAPVGLYQGNHVALCYIGEEAEARIKKPTVLREVWLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLKDVLRNSDHEMDWIFKLSFVYDIVNGMLFLHGSPLRSHGNLKPSNCLVDSHMQLKLAGFGLWEFKHGSTCRIYNQEATDHSELYWTAPELLRLRELPWSGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEEIISCIKDPRAPVPLRPSLLEDKGDERIVALVRACWAESPEQRPAFPSIKKTLREASPRGRVSILDSMMGKLEMYASHLEEVVEERTCQLVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQTHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMSLHLLSVTTNFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTARALLVAGGYHLQKRGTISVKGKGEQTTFWLTGKDGFAVPLPEFTEEEAKVPEIL
Protein: Down syndrome cell adhesion molecule 1, isoform F (Q0E9H5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVAQYYEADVNKEHVIRGNSAVIKCLIPSFVADFVEVVSWHTDEEENYFPGAEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIASVGPRLLSGNDIKVLQFSASQASTLLCPAQSYPVPVFRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVAPKIASFDFGEEPLNYGEPASVQCTILGGDLPMNVTWLLNNATIDSFHDISFSRIGKRINVLSIESVSAHHAGFYSCHAQNKAGITAHSARLIVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Tricyclene synthase, chloroplastic (EC 4.2.3.105) ((E)-beta-ocimene synthase 0e23) (EC 4.2.3.106) (Myrcene synthase 1) (EC 4.2.3.15) (Terpenoid synthase 10) (AtTPS10) (Q9ZUH4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in monoterpene (C10) biosynthesis. The major product is beta-myrcene (56%) followed by (E)-beta-ocimene (20%) and minor amounts (less than 5%) of the cyclic monoterpene (-)-limonene, (+)-limonene, 2-carene and tricyclene.
Subcellular location: Plastid, chloroplast stroma {ECO:0000250}.
Interaction partners:
- S-
- Beta-myrcene/
- 1,8-cineole synthase 1, chloroplastic
- Putative inactive
- Farnesyl pyrophosphate synthase 2
- Solanesyl diphosphate synthase 1, chloroplastic
- Solanesyl diphosphate synthase 2, chloroplastic
- Gamma-glutamyl peptidase 4
- Probable alpha,alpha-trehalose-phosphate synthase 11
- Geranylgeranyl pyrophosphate synthase 6, mitochondrial
Sequence:
MATLLQIGSGVIYSNALRKTLRRPQSSTCIIVTETTPCNKSPTVQRRSANYQPSRWDHHHLLSVENKFAKDKRVRERDLLKEKVRKMLNDEQKTYLDQLEFIDDLQKLGVSYHFEAEIDNILTSSYKKDRTNIQESDLHATALEFRLFRQHGFNVSEDVFDVFMENCGKFDRDDIYGLISLYEASYLSTKLDKNLQIFIRPFATQQLRDFVDTHSNEDFGSCDMVEIVVQALDMPYYWQMRRLSTRWYIDVYGKRQNYKNLVVVEFAKIDFNIVQAIHQEELKNVSSWWMETGLGKQLYFARDRIVENYFWTIGQIQEPQYGYVRQTMTKINALLTTIDDIYDIYGTLEELQLFTVAFENWDINRLDELPEYMRLCFLVIYNEVNSIACEILRTKNINVIPFLKKSWTDVSKAYLVEAKWYKSGHKPNLEEYMQNARISISSPTIFVHFYCVFSDQLSIQVLETLSQHQQNVVRCSSSVFRLANDLVTSPDELARGDVCKSIQCYMSETGASEDKARSHVRQMINDLWDEMNYEKMAHSSSILHHDFMETVINLARMSQCMYQYGDGHGSPEKAKIVDRVMSLLFNPIPLD
Protein: Histamine H4 receptor (H4R) (HH4R) (Q91ZY1)
Organism: Rattus norvegicus (Rat)
Function: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist) (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9H3N8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9H3N8}.
Interaction partners:
- Histamine H1 receptor
- Histamine H2 receptor
- Histidine decarboxylase
Sequence:
MSESNGTDVLPLTAQVPLAFLMSLLAFAITIGNAVVILAFVADRNLRHRSNYFFLNLAISDFFVGVISIPLYIPHTLFNWNFGSGICMFWLITDYLLCTASVYSIVLISYDRYQSVSNAVRYRAQHTGILKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTEECEPGFVTEWYILAITAFLEFLLPVSLVVYFSVQIYWSLWKRGSLSRCPSHAGFIATSSRGTGHSRRTGLACRTSLPGLKEPAASLHSESPRGKSSLLVSLRTHMSGSIIAFKVGSFCRSESPVLHQREHVELLRGRKLARSLAVLLSAFAICWAPYCLFTIVLSTYRRGERPKSIWYSIAFWLQWFNSLINPFLYPLCHRRFQKAFWKILCVTKQPAPSQTQSVSS
Protein: Neuronal PAS domain protein 3 (F8VR32)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRAGAAANGTPQNVQGITSYQQRITAQHPLPNQSECRKIYRYDGIYCESTYQNLQALRKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTISYLKMRDFANQGDPPWNLRMEGPPPNTSVKGAQRRRSPSALAIEVFEAHLGSHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHPGDHVEMAEQLGMKLPPGRGLLSQGTAEDGASSASSSSQSETPEPVESTSPSLLTTDNTLERSFFIRMKSTLTKRGVHIKSSGYKVIHITGRLRLRVSLSHGRTVPSQIMGLVVVAHALPPPTINEVRIDCHMFVTRVNMDLNIIYCENRISDYMDLTPVDIVGKRCYHFIHAEDVEGIRHSHLDLLNKGQCVTKYYRWMQKNGGYIWIQSSATIAINAKNANEKNIIWVNYLLSNPEYKDTPMDIAQLPHLPEKTSESSETSDSESDSKDTSGITEDNENSKSDEKGNQSENSEDPEPDRKKSGNACDNDMNCNDDGHSSSNPDSRDSDDSFEHSDFENPKAGEDGFGALGAMQIKVERYVESESDLRLQNCESLTSDSAKDSDSAGEAGAQASSKHQKRKKRRKRQKGGSASRRRLSSASSPGGLDAGLVEPPRLLSSPNSASVLKIKTEISEPINFDNDSSIWNYPPNREISRNESPYSMTKPPSSEHFPSPQGGGGGGGGGGGLHVAIPDSVLTPPGADGAAARKTQFGASATAALAPVASDPLSPPLSASPRDKHPGNGGGGGGGGGGAGGGGPSASNSLLYTGDLEALQRLQAGNVVLPLVHRVTGTLAATSTAAQRVYTTGTIRYAPAEVTLAMQSNLLPNAHAVNFVDVNSPGFGLDPKTPMEMLYHHVHRLNMSGPFGGAVSAASLTQMPAGNVFTTAEGLFSTLPFPVYSNGIHAAQTLERKED
Protein: Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69) (P97411)
Organism: Mus musculus (Mouse)
Function: May play a role in neurotransmitter secretion.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:11029035}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
Interaction partners:
- PRKCA-binding protein
- Ras-related protein Rab-2A
Sequence:
MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQYRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEGKKTSWRENREAVAPEPRQLISLEDEHKDSSAYKTEEGTSVLSSVDKGSVHDTCSGPIDELLDGKPEEACLGPTAGTPEPESGDKDDLLLLNEIFSTSCLDEGEFSREWAAVFGDDQLKEPAPMGAQGEPDPKPQIGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA
Protein: Transcription factor TOG1 (Transcriptional regulator of oleate 1) (P39961)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcriptional activator required for growth on non-fermentable carbon sources and that regulates genes involved in fatty acid utilization. Acts as a direct activator that binds the promoters of oleate utilizing genes, encoded key enzymes in beta-oxidation and NADPH regeneration (POX1, FOX2,POT1 and IDP2), the glyoxylate shunt (MLS1 and ICL1), and gluconeogenesis (PCK1 and FBP1). Regulates also the abundance of peroxisomes that are vital for fatty acid oxidation.
Subcellular location: Nucleus {ECO:0000269|PubMed:24998441}.
Interaction partners:
- Protein STU2
- Tubulin beta chain
- ATP-dependent helicase ULS1
- Protein STU1
Sequence:
MAAKRGLAKQKSRVTKACDRCHRKKIKCNSKKPCFGCIGSQSKCTYRNQFREPIEAFFNYTGSLSNDLDNAKCSIAKLKAQLPPSAPASLQKGLANICTELEKIQPQLYLNLDSKEISSYGGLKSIETEIIGKQSKSLNRFSNAFESNTAQNVSMYFGVYSPLLYFASTGISWITKKLISCSNDRETRETIYLFLKFLDASSASHAGPKVTSISPLEYYSKLNGLSCGNDVLIQHIMSNISNEIKGNTNINQTIKFNKPTDWFMYGVQLMEQHHKALDRKSSKKLLPLKYFLEQDELIFCLCLEYFERSLFSTMYDLTILKGLVSLMKHRYWIDDPFVLGRIISTMSRRSLDAGLNRWEYYIGQDEDTAEEYRKLWWDCYWWDRWYSLVTGKQPLIPHEMTSCLFPKDVVGLGVDDSMDCFTLINLVELDPSKFDICISFGYILLTKIITAVFSGLLYNRHFTDYRLFATPNAKDLNGTARQLMVEFSKICKIFQCIQDKLIPFLKQYSENSNVFELYTHFGFAKVCCFQGMESLILRIQNLLQERERIELDSCVKDIRLQTFEASVDILTDVLKHEDTFYIFRCSWFIYAILMNITLNFIETPRRNSICYLSLMCRMIASYNDLFVSSGNVNFKGNNAFSKKLENGTAVSFILTRICCQMYTRSQKMAKESLFCELKKYGQACSDAGQAALDIECIWYRNIIGEHKESSFRKEILSILDREMGDLVNNRVIGVQGKNQEGACYEKLSPSSTSVSVGMDFCSLENFVTAESLPDLLNLFWEDTEFGITKENLGE
Protein: VPS39 subunit of HOPS complex (E9PT04)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
Sequence:
MTLLSRCRSWRSFHCRLTAWLPGEWLLVGTKQGHLLLYRIRKDVGCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHTETGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDAKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVLNEEGICTQKCALNWTDIPVAMEHQPPYIVAVLPRYVEIRTLEPRLLVQSIELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPTLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKQKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSIWVLRDFPEDGLKIFTEDLPEVESLPRDRVLNFLIENFKALAIPYLEHIIHVWEETGTRFHNCLIQLYCEKVQNLMKDYLLSLPTGKSPVPAGEEAGELGESRQKLLTFLEISSSYDPGRLICDFPFDGLLEERALLLGRMGKHEQALFIYVHVLKDTKMAKEYCHKHYDQNKEGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNSADT
Protein: Large ribosomal subunit protein uL30m (39S ribosomal protein L30, mitochondrial) (Q9W4I3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Large ribosomal subunit protein uL23m
- Small ribosomal subunit protein uS15m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein uL22m
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein mL41
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein mL40
Sequence:
MNLGRLLNPLRSTACSVRSYGKHNKKFLYKNGQKFEGITYYPRTPDHQDPPVEPAKLFRVQRIKPLKGNPYWENRILKDLGLDGKQSDFTVVKNIPENNARLWKIKHLIKVTPVTFPYGEPTAQDVRHTILKENGECLVTKDLGPIDTRLAARQDYDEQPKRLDTDLLRKDARLKWLNPW