wanglab/gogpt-training-data huggingface dataset:
Protein: Flagellar biosynthesis protein FlhF (Flagella-associated GTP-binding protein) (Q01960)
Organism: Bacillus subtilis (strain 168)
Function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- Flagellar biosynthesis protein FlhA
- Flagellum site-determining protein YlxH
- Flagellar motor switch protein FliM
- Flagellar biosynthetic protein FlhB
- Flagellar motor switch protein FliG
- Flagellar M-ring protein
- Flagellar biosynthetic protein FliR
- Flagellar biosynthetic protein FliZ
- Flagellar biosynthetic protein FliQ
- Protein-glutamate methylesterase/protein-glutamine glutaminase
Sequence:
MKIKKFTAASMQEAALLIRKELGNEAVILNSKKIKKRKWFGLVNKPAVEVIAVLDQDFLEKKTPQKAAEPKQTLKTPVSSPKIEERTYPPQIPAQQELGDFSAYQSVLPEPLRKAEKLLQETGIKESTKTNTLKKLLRFSVEAGGLTEENVVGKLQEILCDMLPSADKWQEPIHSKYIVLFGSTGAGKTTTLAKLAAISMLEKHKKIAFITTDTYRIAAVEQLKTYAELLQAPLEVCYTKEEFQQAKELFSEYDHVFVDTAGRNFKDPQYIDELKETIPFESSIQSFLVLSATAKYEDMKHIVKRFSSVPVNQYIFTKIDETTSLGSVFNILAESKIGVGFMTNGQNVPEDIQTVSPLGFVRMLCR
Protein: Serotonin N-acetyltransferase (Serotonin acetylase) (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (AA-NAT) (O88816)
Organism: Mus musculus (Mouse)
Function: Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q16613}.
Interaction partners:
- Acetylserotonin O-methyltransferase
- Aromatic-L-amino-acid decarboxylase
- Amine oxidase [flavin-containing] A
- Amine oxidase [flavin-containing] B
- Indoleamine 2,3-dioxygenase 2
- Indoleamine 2,3-dioxygenase 1
- Indolethylamine N-methyltransferase
- 14-3-3 protein zeta/delta
- N-acetyltransferase ESCO1
- N-acetyltransferase ESCO2
Sequence:
MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC
Protein: AT3g02420/F16B3_5 (Dihydroflavonol 4-reductase/flavanone protein) (F16B3.5 protein) (Q9M898)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAEGGEDSQRLKKIAAAAFDYENDARWADYWSNILIPPHMASRPEVVDHFKRKFYQRYIDPDLVVEPMSTSSSSSQSARPTATSASSTASSNANEQVRSRNSGSVPRTSGPSATTGATPSSMRWDEQTIQFSVNAWVFVIAVLAVLPLIPKNLSNRAYRLSFMGTACSSLYSLYSLYGRPRAWNMQGLQVYFQSIVAAKDFIYFIYCLTFVTSHLCLKFALIPILCRALEQVAKFLRRNFGRSTIYRKYLEDPCVWVESNTTTLNILSSQAEIAIGFLLIISLLSWQRNIIQTFMYWQLLKLMYQAPVTAGYHQSTWSRIGRTVTPIIQRYAPFLNTPVSAVQRWWFR
Protein: poly(A)-specific ribonuclease (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase) (Glucose-repressible alcohol dehydrogenase transcriptional effector) (Q7K112)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKGNHYKMSRNKDKYDSANRRQQIFLSQEDIAAGKKTNWSGLEITGCVRNISPSLWEFEHLTALYLNDNQLLRLPADVGMLTSLRTLDLSSNKLRSLPAELGELIQLRELLLNNNFLRVLPYEIGKLFHLVILGLMGNPLQKEFMNIYNEPNGTQKLLTYMLDNLSFTVNPPPQRPWLPLAKPNKTRPACIFTVMCYNVLCDKYATRQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMANAEGSDNMLNRVMPKDNIGLAALLKVKENAWEPMSEVTQISQPLLVCTAHIHWDPEFCDVKLIQTMMLSNELKTIIDEASHSFRPGHKNDSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMDHLDFKDMGYKSCLQRLLSNDTNEFTHSFKLASAYNEDIMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVELELMHTASQQAPPNGLINRR
Protein: Signal peptide peptidase like 2B (A0A087WT77)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XGTVAIGGYWAGSRDVKKYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKAC
Protein: Proteasome regulatory ATPase subunit 1 (Q9NCA0)
Organism: Trypanosoma brucei
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MASEKGGCQTKNTVRIKGENEEEKEIIPLDQDDIALLKLYGSGPYHATVKELEEFVKTKAEAVNKLAGTRDNELGLAPPVQWDLNSDQEVMRSENSLHVARCTRIINKGQDDAKYVVAIRDTAKYVVKLGNRVARQDIEESMRVGVLVGYSSIHIEIPLPPRVDPSVSMMQVEEKPDVTYNDVGGAKEQIDRIREVVELPLTNPEKYTQLGIDPPKGVLLYGPPGTGKTLLAKAVANRTDATFIRVIGSELVQRYIGEGARMIREIFQLARTKKAAIIFFDEVDAVGGARGGGDGDDEIQRTMLEMVNQMDGFDSRGNIKVIMATNRPDTLDPALTRPGRMDRKLEVGLPDLEGRTKILRIHAKSLSCEKAIRFELIARLCPNATGADLRSVCTEAGMFAIRARRKTINEKDFLDAVNKVIKGHHKFSATAKYMVYN
Protein: Probable phosphoribomutase (PRM) (EC 5.4.2.7) (Phosphoglucomutase 3 homolog) (PGM 3 homolog) (O74478)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Converts ribose 1-phosphate to ribose 5-phosphate. Involved in ribose salvage via the pentose phosphate pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Phosphoglucomutase
- Probable UTP--glucose-1-phosphate uridylyltransferase
- Probable UTP--glucose-1-phosphate uridylyltransferase
- Glucose-6-phosphate isomerase
- Hexokinase-1
- Hexokinase-2
- Ribokinase
- Probable transketolase
- Ribose-5-phosphate isomerase
- Ribose-phosphate pyrophosphokinase 1
Sequence:
MDPILQELVDEWFKLDQDETTRNEVSQLIKAEDYATLKQIMHPRIGFGTSGLRAEIGAGFARMNCLTVIQASQGFAEYLLQTVPSAAKLGVVIGHDHRHKSNTFARLTAAVFLQKGFKTYFFDHLVHTPLVPFAVKTLGTAAGVMITASHNPAAYNGYKVYWGNGCAIIPPHDKGIAACIEKNLTPITWDKNLVENHKLADRDFAVGLLKNYWSQLHEFHSENNFSLEMKSLKFVYTPIHGVGLPFVTSALHLFGEQGDMISVPLQDSPNPDFPTVKFPNPEEEGALDLAYEQADANGISYVLATDPDADRFAFAEKINGAWRRFTGDEVGCILAYFIFQEYKNVGKPIDDFYVLSTTVSSAMVKSMAKVEGFHHVETLTGFKWLGNKALELEKQGKFIGLAYEEALGYMVGSIVRDKDGVNALITFLHLLKRLQLQNLSITEVFEQMSKKYGYYTTQNSYFLSRDTPKLRALVDALRHYDTKSGYPATLGSKKITNVRDLTTGYDSSSTDGKATLPVSKSSDNVTFELENGEVIMTIRTSGTEPKLKFYICARGHSLEDSIKNATEVKQAIKSEWFHPQQNGLEEP
Protein: L-aspartate/L-glutamate decarboxylase (ADC/GAD) (EC 4.1.1.11) (EC 4.1.1.15) (PhGAD) (O58679)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine, and the decarboxylation of L-glutamate to produce 4-aminobutanoate. Can also use cysteate and, to a lesser extent, cysteine sulfite (3-sulfino-L-alanine), but not L-tyrosine. Specific activities toward L-aspartate and cysteate are higher than toward L-glutamate.
Interaction partners:
- 438aa long hypothetical aminotransferase
- Alanine/serine racemase
- Ornithine aminotransferase
- Broad substrate specificity amino-acid racemase
- 4-phosphopantoate--beta-alanine ligase
- Aspartate aminotransferase
- histidinol-phosphate transaminase
- L-asparaginase
- L-aspartate oxidase
- Plant-type L-asparaginase
Sequence:
MKFPRIGLPKEKVIELINEKTKKDLTFSSGKILGSMCTMPHDLAIEVYTKYIDRNLGDPGLHPGTRKIEEEVIEMISDLLHLEKGHGHIVSGGTEANILAVRAFRNLSDVEKPELILPKSAHFSFIKAGEMLGVKLVWAELNPDYTVDVRDVEAKISDNTIGIVGIAGTTGLGVVDDIPALSDLARDYGIPLHVDAAFGGFVIPFAKELGYELPDFDFKLKGVQSITIDPHKMGMAPIPAGGIVFRRKKYLKAISVLAPYLAGGKVWQATITGTRPGASVIAVWALIKHLGFEGYMRIVERAMKLSRWFAEEIKKINNAWLVREPMLNIVSFQTKNLKKVERELKSRGWGISAHRGYIRIVFMPHVTREMIEEFLKDLKEVLS
Protein: COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP) (Q7L5N1)
Organism: Homo sapiens (Human)
Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity. Stabilizes COP1 through reducing COP1 auto-ubiquitination and decelerating COP1 turnover rate, hence regulates the ubiquitination of COP1 targets.
Subcellular location: Nucleus {ECO:0000269|PubMed:9535219}. Cytoplasm {ECO:0000269|PubMed:9535219}.; SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000269|PubMed:9520381}. Note=(Microbial infection) The interaction with HIV-1 Vpr protein possibly leads its translocation to a perinuclear region. {ECO:0000269|PubMed:9520381}.
Interaction partners:
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 2
- COP9 signalosome complex subunit 7a
- COP9 signalosome complex subunit 8
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 7b
- Ubiquitin-like protein NEDD8
- COP9 signalosome complex subunit 9
Sequence:
MAAAAAAAAATNGTGGSSGMEVDAAVVPSVMACGVTGSVSVALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDKEYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSVFESVIDIINGEATMLFAELTYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQHSAIKMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCLPVLSTDKFKTDFYDQCNDVGLMAYLGTITKTCNTMNQFVNKFNVLYDRQGIGRRMRGLFF
Protein: Heat shock protein 60 (Q8IJN9)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Heat shock protein 70
- 20 kDa chaperonin
- 10 kDa chaperonin
- 60 kDa chaperonin
- T-complex protein 1 subunit theta
- Endoplasmic reticulum chaperone GRP170
- Endoplasmic reticulum chaperone BIP
- GrpE protein homolog
- Heat shock 70 kDa protein
- Heat shock 70 kDa protein
Sequence:
MISTLRGKIFNNGSNRNKCVSILSNIQKRNISKDIRFGSDARTAMLTGCNKLADAVSVTLGPKGRNVIIEQSFGSPKITKDGVTVAKSIEFNNKLANLGAQMVKQVAANTNDKAGDGTTTATILARSIFQQGCKAVDSGMNPMDLLRGINKGVEKVLEYLNSIKKDVTTTEEIFNVASISANGDKNIGQLIADTMKKVGKEGTITVTEGKTLQHELEIVEGIKFDRGYISPYFINNSKDQKVELDKPYILIHEKKISTVKSLLPVLEHVLQNQSSLLVIAEDVDSDALATLIVNKLRLGLKICAVKAPGFGEHRKALIHDIAVMTGAKVITEETGLKLDDPQVVSYLGKAKSINVTKDSTLIMEGEGKKEEINERCESIRNAIKMNTSDYEKEKLQERLAKITGGVALIKVGGISEVEVNEIKDRIQDALCATKAAVEEGIVPGGGSALLFASKELDSVQTDNYDQRVGVNIIKDACKAPIKQIAENAGHEGSVVAGNILKEKNSNIGFNAQEGKYVDMIESGIIDPTKVVKTAISDAASIASLMTTTEVAIVDFKDSKNEESSQHMNSVNSMGDMGGMY
Protein: Tryptophan synthase beta chain (EC 4.2.1.20) (Q72EU8)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Tryptophan synthase alpha chain
- indole-3-glycerol-phosphate synthase
- Anthranilate phosphoribosyltransferase
- N-
- Anthranilate synthase, component I
- Anthranilate synthase, glutamine amidotransferase component
- Tryptophan synthase beta chain
- Serine hydroxymethyltransferase
- Tryptophanase
- Aminotransferase, class V
Sequence:
MKKGYFGDFGGRFVPELLMPPLMEIEAAMRDIMPTQAFRHELDDLLHNFAGRETPLTRCDTLSRELGCTLWLKREDLLHTGAHKVNNTLGQALLARRMGKTRLVAETGAGQHGVATAAAAARLGLSCIVFMGAVDVERQSANVMRMKLLGAEVVPVESGTRTLKDAINETLRYWIAEQGSTHYCFGTAAGPHPFPTLVRDFQAVIGHETRRQMLERTGALPDMVVACVGGGSNAIGMFHAFVDDADVRIVGVEAAGTGEPGCYNSAPINLGSPGVLHGNRTMLLQDGDGQILPSHSVSAGLDYPGVGPEHAHLGATGRVVYGMVTDTQALAAFKALTRAEGIIPALESSHAVAWVLENPHLLPQGGNVVVNLSGRGDKDMDIVREHLFPSLGGKA
Protein: Symplekin scaffold protein (A0A087WUE9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASGSGDSVTRRSVASQFFTQEEGPGIDGMTTSERVVDLLNQAALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVISELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDTRKRPRDDSDSTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFNSGLKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGASGSLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVVRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKGEALPPHSSGLAPATPGQDLSHPHAPTGICQVKDCHSQPHLRALESHLPPSLLFLPPLPSLPPSLLLPSSQVLPFTTHLFLPLMYLLCPGTEWA
Protein: 3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (E9PER6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
Protein: ATPase cation transporting 13A2 (A0A8I5ZTP8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
LSTDSSPLLGSTPPSYGTLMTGTSIDPLSSSVSSVRLSGYCGSPWRAIGYHAAVWMLAGIPWLLFRWKPLWGVRLRLRPCSLARAETLVIEIRDKEGSSRQLFTVQVQTEAVVDGSLELPSQAKAEDGRSLAAVGVAPESMWQDTTQLHRQKEAKQVLRYYILQGQRYVWMETQQAFCQVSLLDHGRACDDIHCSSSGLSLQDQAVRKTIYGPNVIGIPVKSYLQLLVDEALNPYYGFQAFSIALWLADHYYWYAVCIFLISAISICLSLYKTRKQSMTLRDMVKLSVRVQVCRPGGEEEWVDSSELVPGDCLVLPQEGGMMPCDAALVAGECVVNESSLTGESIPVLKTALPEGPQPYCPETHRRHTLFCGTLVLQARAYLGPRVLAVVTRTGFCTAKGGLVSSILHPRPISFKFYRHSMKFVAALSVLALLGTIYSIIILYRNRVPVKEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKLRLVCFDKTGTLTEDGLDIMGVVPLKGQMLLPLVPEPCHLPPGPLLRALVTCHALSQLHDTLVGDPMDLKMVESTGWVLEEGSAAGSAPETQVLVVMRPPPRGPQQQEESPEPVSVLRRFPFSSALQRMDVVVTWPGATQPEAYVKGSPELVASLCSPETGEGGSGGGLRSVTHTSLPTSPDDTCQPSRDTVEQELSLLGLLVMRNLLKPQTTPVIQTLRKTGIRTVMVTGDNLQTAVTVAKACGMVGTQEHLAIIHATHPEQGQPAALEFLPTEPSAAMNGAKDPVQATDYPVEPESQSRHLALSGSTFAVLQKHFPKLLPKVLVQATVFARMAPEQKTQLVCELQRLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPTVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLFITTTVAVLMSRTGPALTLVRARPPGALLSVPVLGSLLLQVALVAGIQLGGYFLVIAQPWFVPLNRTVPAPDNLPNYENTVIFSLSGFQYLILAAAVSKGAPFRQPLYTNGLRNIADSSFKLLLLGLVAFNFVGAFMLESVLDQCLPACLQWLRPKRASKKQFKQLQRELAERPWPTLPVGSVR
Protein: Chymotrypsin-like elastase family member 1 (EC 3.4.21.36) (Elastase-1) (Q91X79)
Organism: Mus musculus (Mouse)
Function: Acts upon elastin.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P00772}.
Interaction partners:
- Carboxypeptidase A1
- Carboxypeptidase A2
- Bile salt-activated lipase
- Syncollin
Sequence:
MLRFLVFASLVLCGHSTEDVPETDARVVGGAEARRNSWPSQISLQYQYGGSWHHTCGGTLIRSNWVMTAAHCVDSPMTYRVVVGEHNLSQNDGTEQYVNVQKIVSHPYWNKNNVVAGYDIALLRLAKSVTLNNYVQLGVLPREGTILANNSPCYITGWGRTRTNGELAQTLQQAYLPSVSYSICSSSSYWGSSVKNTMVCAGGDGVRSGCQGDSGGPLHCMVNGQYAVHGVTSFVSSMGCNVARKPTVFTRVSAYISWMNNVIASN
Protein: BAG cochaperone 4 (BCL2-associated athanogene 4) (Q5XIR5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHVPPPLYHPLRPEPPQPPVSWRGRGGAPAETTWPGEGAGGDGYYPSGGAWAEPSRAGGGHQEQPPYPGYNSNYWNSVRPRAPYPSTYPMRPELQGQSLNSYANGAYGPPYPPGPATASAASYSGAYYVPGYAQGTYSTDIPSTYRSPGNSPTPVSRWMYPQQDCPTEAPPLRGQVPGYPASQNPAMTLPHYPYGDGNRTVPQSGATGRPQDDAWASSAYGMGARYPWPSAAPSAPSGNLYMTESASPWPGNSSPQPPPSPPPQQPKDSSYSYSQSGQGMNRHSFPCSVRQYESPGAVNNDESDLLDSQVQYSAEPQLYGNTSSEHPSNQVPSNNLPEECFSSDEGTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL
Protein: Transcription factor Sox-12 (Sox-K1 protein) (XSox-K1) (Transcription factor Sox-33) (xSox-33) (xSox33) (Q8AXQ4)
Organism: Xenopus laevis (African clawed frog)
Function: Transcription factor that binds to the sequence 5'-AACAAT-3'. Acts as a transcriptional activator (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O15370, ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
Sequence:
MVQNKTTGSCPKPTEVAPGGPSWCKTSNGHIKRPMNAFMVWSQIERRKLMSLCPNMHNADISRSLGQRWKLLQDTDKIPYVREAERLRLKHMADYPNYKYRPRRRSRTQESKTRARLPRSTATCQSVPSPCLSQMDTGSSMQWGETCPAWGGDQVGQSVETQIRESSARSPEVPTHTKTVPSSPQSAEEHEGLEGGSLVIPVDKEVPPHSGSHFEFPDHCTPEVMEMISGSGLLESVPDLVFSY
Protein: Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (CD antigen CD87) (P35456)
Organism: Mus musculus (Mouse)
Function: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000250|UniProtKB:P49616}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:P49616}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000250|UniProtKB:P49616}.
Interaction partners:
- Urokinase-type plasminogen activator
- Vitronectin
- Plasminogen activator inhibitor 1
- Plasminogen
- Integrin beta-1
- Glia-derived nexin
- Plasminogen activator inhibitor 2, macrophage
- Metalloproteinase inhibitor 1
- Tissue-type plasminogen activator
- Epidermal growth factor receptor
Sequence:
MGLPRRLLLLLLLATTCVPASQGLQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPRPGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSNQTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCATASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPTGGAPRPGPAQLSLIASLLLTLGLWGVLLWT
Protein: Cytochrome c-type cyt cy (Q05389)
Organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Function: Electron transfer pathways that operates during photosynthesis.
Subcellular location: Cell membrane; Single-pass membrane protein.
Interaction partners:
- Cytochrome c1
- Ubiquinol-cytochrome c reductase iron-sulfur subunit
- Cbb3-type cytochrome c oxidase subunit CcoP
- Cytochrome b
- Cytochrome c2
- Cytochrome c2-2
- cytochrome-c oxidase
- Cytochrome c oxidase, Cbb3-type, biogenesis protein CcoH
- Cytochrome c oxidase, Cbb3-type, subunit II
- Protein SenC
Sequence:
MLVKTHITKIGVTLFAVALFYGFIYMLSNSLFATRPATAVAVGADGKALLPSVDEAAMPAKAPAAAAPAAETAEAAAPAEPAAPPPPAYVEVDPATITGDAKAGEEKFNKTCKACHKIDGKNAVGPHLNGVIGRATATVEGFKYSTAMKNHVGNWTPERLDIYLVSPKAEVPGTKMSFVGLPEAADRANVIAYLNTLPR
Protein: FI09246p (Growth arrest and DNA damage-inducible 45) (A1Z6W5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Aurora kinase
- Proliferating cell nuclear antigen
- Mitogen-activated protein kinase kinase kinase 4
Sequence:
MVVEENCSMHHLERELDLELEIDMAMECAPIGRTIKSALLRAQSEARVIVGLSAAINVLSKSPEGSLFCLMAQPKDGDSATHMHEVLLEAFCYENDIYVIKVDDATKLSRILGQDSVESCCLVQKVWADAPEEQLTKAENQLVDYCEAHWDAPQQPIVQLPAV
Protein: SNF2 domain-containing protein / helicase domain-containing protein / zinc finger protein-like protein (F4HTG1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- RuvB-like protein 1
- Chromatin structure-remodeling complex protein SYD
- Actin-related protein 5
- Actin-related protein 4
- Probable inactive histone-lysine N-methyltransferase SUVR1
- Nuclear transcription factor Y subunit C-1
- L-ornithine N5-acetyltransferase NATA1
- Protein EIN6 ENHANCER
- DNA-binding protein-like
Sequence:
MGEEGSMFGLGGEFPVDDCDGGFEFEDDDETIDIETLYRILDEKPDSAEGSQENLSPVGSSADELKDSQLLNGSFDEHVKMEAGLSPSPAHTCSASLKDWFSLSQGEQPVETCGVSQSEMTSCSISSSFSDPDGNMMAFNPVNCDVDTVSKQDDKIIDSKSMLTPYFDNVTGYGVGLGANHNSSAMSVFFNNSNSLSDSADNYVSSAQDCYNTSGTSLSDHTPNSVQNFAFEFFPNKEEAVNDVESGVSESQSDGASRMIFDRHGRVDNGSLERKPPIDFSSARGISFKFESNPSVSPACVKPYNSFDSHLADSDLDRPNNYSCSFQDNKTVHVKVKPEAESEKVVYSSVPGEFSVRDDAYLSGETNRWWSGASSSAVSYQTDIEKGYSYMAPQTALPSQDSGKISSNHFYDSDTCLQYVVEDPSPVTQNNEYKDFQIQQGDREYIQPRGIDSQFSNASFESVQSHSSECISDSDDDSDVCIIEPYGQSAIPHRPLAMKMPVVSSEYSTVSHNFNQSGGLKLQSNKENMIFQAALQDLTQPNSEAILPDGVLTVPLLRHQRIALSWMAQKETSGFPCSGGILADDQGLGKTVSTIALILKERSKPAQACEESTKKEIFDLESETGECAPLKPSGRSKHFEHSQLLSNENKVGGDSVGKVTGRPAAGTLVVCPTSVMRQWADELHKKVTSEANLSVLVYHGSSRTKDPHELAKYDVVVTTFSIVSMEVPKQPLVDDEDEEKDGVHDGGTAATGFCSNKKRKYPPDSKKKGSKKKKVEFLSGPLAKVSWFRVVLDEAQSIKNYKTQVARACWGLRAKRRWCLSGTPIQNSIDDLYSYFRFLKYDPYSSYVLFCSTIKNPITRNPVKGYQKLQAILKTVMLRRTKGSLLDGKPIISLPPKSIELRKVDFTVEERDFYSKLEAESRTQFREYAEAGTVKQNYVNILLMLLRLRQACDHPLLVNGEYSFTWESSVGLAKKQIQSDASLAICGICNDAPEDAVASVCGHVFCKQCIYERLTGDSNHCPFANCNVRLTISSLSSKTRLDDAMPDMQERATSNSLSPCSDEDLPYGSSKIKAALEILQSLPKAHDLTDSNQISENREYSGLSITPVKNEGMSVDVPIKVAGEKAIVFSQWTKMLNLLEASLVSSHIQYRRLDGTMSVAARDKAVQDFNTLPEVTVMIMSLKAASLGLNMVAACHVLMLDLWWNPTTEDQAIDRAHRIGQTRPVTVVRFTVKDTVEDRILALQQKKRMMVASAFGEDEKGSRQSHLTVEDLSYLFMADS
Protein: Phorbol-12-myristate-13-acetate-induced protein 1 (PMA-induced protein 1) (Immediate-early-response protein APR) (Protein Noxa) (Q13794)
Organism: Homo sapiens (Human)
Function: Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:15705586, ECO:0000269|PubMed:17374615}.
Interaction partners:
- Induced myeloid leukemia cell differentiation protein Mcl-1
- Bcl-2-like protein 1
- Apoptosis regulator Bcl-2
- Bcl-2-related protein A1
- Bcl-2-like protein 2
- Bcl-2-like protein 11
- Bcl-2-binding component 3, isoforms 3/4
- Cellular tumor antigen p53
- BH3-interacting domain death agonist
- Bcl-2-interacting killer
Sequence:
MPGKKARKNAQPSPARAPAELEVECATQLRRFGDKLNFRQKLLNLISKLFCSGT
Protein: MYB-like transcription factor ETC3 (Protein CAPRICE-like MYB3) (Protein ENHANCER OF TRY AND CPC 3) (Q9M157)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: MYB-type transcription factor involved in epidermal cell fate specification. Acts as a negative regulator of trichome development, including endoreplication, by mediating lateral inhibition. Promotes the formation of hair developing cells in H position in root epidermis, probably by inhibiting non-hair cell formation. May have pleiotropic effects on flowering development and epidermal cell size through the regulation of endoreduplication.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription factor EGL1
- Transcription factor GLABRA 3
- Homeobox-leucine zipper protein GLABRA 2
- Protein TRANSPARENT TESTA GLABRA 1
- Protein TORMOZ EMBRYO DEFECTIVE
- Transcription factor MYC1
- Uncharacterized protein At2g30430
- RING-type E3 ubiquitin transferase
- Transcription factor MYB21
- Zinc finger protein GIS2
Sequence:
MDNHRRTKQPKTNSIVTSSSEEVSSLEWEVVNMSQEEEDLVSRMHKLVGDRWELIAGRIPGRTAGEIERFWVMKN
Protein: H-2 class I histocompatibility antigen, D-D alpha chain (H-2D(D)) (P01900)
Organism: Mus musculus (Mouse)
Function: Involved in the presentation of foreign antigens to the immune system.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
Sequence:
MGAMAPRTLLLLLAAALGPTQTRAGSHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWGKEEPPSSTKTNTVIIAVPVVLGAVVILGAVMAFVMKRRRNTGGKGGDYALAPGSQSSDMSLPDCKV