wanglab/gogpt-training-data huggingface dataset:
Protein: Chromosome partition protein Smc (A0A0H2UQ93)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
Interaction partners:
Sequence:
MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESLRWALGESSVKSLRGGKMPDIIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVERHVYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAIFEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDLEGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQRQDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNSLSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEEADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQKLLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVKSVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKRNRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATTAIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQKEIAEEEASLGSEEATLKTLQDEMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQVEELETLWKLQEEEIDRLSEGDWQADKENCQERLAAISSDKQNLEAEIEEIKSNKNAIQERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKIDNLEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEWIRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEKAIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKSTFEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKALSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGTMAAADSIYGVTMQESGVSKIVSVKLKDLESIEG
Protein: AP complex subunit sigma (Q6PEJ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane, coated pit {ECO:0000256|ARBA:ARBA00004277}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004277}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004277}.
Interaction partners:
- AP-2 complex subunit alpha
- AP-2 complex subunit mu-B
- AP complex subunit beta
- AP-2 complex subunit mu
- AP complex subunit beta
- Intersectin 2a.
- AP complex subunit beta
- Clathrin light chain
- Clathrin light chain
- Intersectin 1
Sequence:
MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE
Protein: DnaJ homolog subfamily C member 15 (Q78YY6)
Organism: Mus musculus (Mouse)
Function: Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9 (By similarity). Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:23530063}; Single-pass membrane protein {ECO:0000269|PubMed:23530063}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM16
- Mitochondrial import inner membrane translocase subunit Tim23
- GrpE protein homolog 1, mitochondrial
- Mitochondrial import inner membrane translocase subunit Tim17-A
- Stress-70 protein, mitochondrial
- Mitochondrial import inner membrane translocase subunit Tim21
- Mitochondrial import inner membrane translocase subunit Tim17-B
- Mitochondrial import inner membrane translocase subunit TIM44
- Mitochondrial import inner membrane translocase subunit TIM50
- Reactive oxygen species modulator 1
Sequence:
MATGGGVTSREGLRYAEYLPPSAQRSDADIDHTAGRRLLAVGLGVAAVAFAGRYAFQIWKPLEQVITATARKISSPSFSSYYKGGFEQKMSKREASLILGVSPSAGKAKIRTAHKRIMILNHPDKGGSPYLASKINEAKDLLEASSKAN
Protein: Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Q6WV17)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers EA2 as substrate. In the larval midgut, required for O-glycosylation of apical and luminal proteins within copper cells enabling proper gut acidification.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- GDP-fucose protein O-fucosyltransferase 2
- Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
- Ras-related protein Rab6
- N-acetylgalactosaminyltransferase 7
Sequence:
MTFSTFTRKMRGRMRSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGGNQVFAYTKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPCSYGKGQQWLMESKFKWQAH
Protein: glycogenin glucosyltransferase (EC 2.4.1.186) (E1JGQ3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRDRLKEVYNVVQEVNVLDSQDAANLALLSRPELGVTFTKLHCWRLVQFEKCVFLDADTLVLQNCDELFEREELSAAPDVSWPDCFNSGVFVFKPSVDTFAQITEFAVKNGSFDGGDQGLLNQFFADWSTADIKKHLPFVYNVTAYASYCYLPAFKQFRDKIKILHFAGKLKPWLIQFNSETKVASVSSEYAHAQDLIQLWWNIFCENVIQSLSTEMAGLAGALSQLRIGQQRTPEQEAYENQMRRQCWESGQIDYTGADSFENIWKKISQTLERKTDKESEETGSS
Protein: Protein kinase, putative (Q389D8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNRSSRNLAEMQDEINQLDDRYKLEKIIGAGSYGVVIRARDTTTNDLVAIKRVNKEIFEEIILAKRILREIKLLAHFHHDNIIGLRNLITPADRDNYDYFYIVMDVMETDLKQVLRTGQSLTEGHIQYFIYQILHALNFIHSSGVIHRDITPANILVNKNCDLKICDFGLSKEESDQGEHMTDYVTMRWYRAPELVMEDKRYSAQIDVWGVGSILGELLGARPLFQGKDRVNQLDKIIDVIGTPSEEDINSIGSTAAQKYLKKKSFRPAPDWASVYPRASPEALDLLRRMLVFHPDKRITVAEALKHPFLRDLYEESDVQVSIQHFNFDETQHKTIQEVKWAVYDESVAFHKNHPRTAPRPQQQQHSAQQPAAAASLPTVDIAGEWRSAQQTIERGEEECGAEQFDKYVGSVE
Protein: long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain-fatty-acid--CoA ligase) (G3V7V3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Long-chain fatty acid transport protein 1
- Platelet glycoprotein 4
- Tyrosine-protein phosphatase non-receptor type 6
- Lysosome membrane protein 2
- Peroxisome proliferator-activated receptor alpha
Sequence:
MLLGASLVGALLFSKLVLKLPWTQVGFSLLLLYLGSGGWRFIRVFIKTVRRDVFGGMVLLKVKTKVRRYLQERKTVPLLFASVVRRHPDKTALIFEGTNTHWTFRQLDDYSSSVANFLQARGLVSGNVVALFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALRHCLDTSKARALIFGSEMASAVYEIQAILDPTLTLFCSGSWEPSTVPANTEHLDPLLEDAPKHLPSIPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPDDIVYDCLPLYHSAGNIVGIGQCVLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAESRHKVRMALGNGLRQSIWTDFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGQPGQLVGRIIQQDPLRRFDGYLNQGANNKKIASDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLQMADVAVYGVEVPGAEGRAGMAAVASPTSNCDLESFAQTLKKELPLYARPIFLRFLPELHKTGTFKFQKTELRKEGFDPSVVKDPLFYLDARTGCYVALDQEAYTRIQAGEEKL
Protein: Hybrid signal transduction histidine kinase D (EC 2.7.13.3) (Q54SP4)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
Interaction partners:
Sequence:
MQDISTTTASTNYLKADGDTGAVFSITSQQQQIHYMRKQKPDHEKTREELIEEINHLRAVSNSNKNARIMLDEMYQFVALLDVNGNLLDVNEPALQGGGMIRSSIQGIPFWDCRWWATSQENIDNVREAVHKASKGEFIRYETEIFGKSAGTEKITIDFSLMPLFNDKGEVSLILPEGRNITEKRLGELEIERKNNELRSLYEKIKELDELKTQFFANVSHELRTPLALIVGPTDKLLKDENVDINVRKDLEIVARNARGLLKIVNNLLDISRLEAGKMNLNYSMVNLGQTVHLIASCFEILAREKSLDFSIITPSEPMMAAIDADKMQRVITNLISNAFKFTPSGGAVKCILEKFDLSPNKPGFQIVVSDTGPGIPDNLHEIIFERFRQVDGSSTRKHGGTGLGLSIVKEFVTLHGGTVTIHNISTGGAQFTLRLPLTPNMDEHLYKKTISDQNISEIQQQLYQQQQQEQQQQQQQQQNLQQPKLILNNIDNKYKINDDDNDDDDDDDDEDGLNFNILKKTNTSSDIASNALKDNMGSIMGVHAIAQQAVEELTEKQFYQSQENIHNKPIVLVVEDNPEMNRFIAELLSKYYFVVTAFDGVEGIEKTRAITPDLIVTDCMMPRMSGDEMVEQLRSDEQFDNIPILLLTAKADENLRIKLLQNGVSDYVNKPFSSEELVARVVNLMTMKKAKQFLQEELSSANTDLQELINQLTNKKRDLQTLVGELEKERNLLNNTNKSKDEFFMNLSHELRTPLNGILGWCQLLLYDIDSGGSSGGGSGSISGDDSTVRTGLETIERCASSQNQLINDLLDMSLIIGDKFSLILGDVDLPILIENAISSILVTAQSKKISVHSNIQGEGEEESSILRNIVGDKARLQQVIWNLLSNSIKFTKEKGRIHLNLKVVNQIPSREVLGFCSNPMFNTINRHGDRWILFTITDNGKGIPKQFLPSVFDRFKQADCSSTRSYGGLGIGLSITQNIIHLHKGAVYANSEGENKGSQFTVVLPIIKGSSSSNSSPSNQLSCSSSPPLIKKPFFSQPTNYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNYNNNNSNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNLNINNLINNNHNNNNNNYHHNNNNNNNSNNNEKLGKRQREEINNNENNNVDLRLRTPPPPPTSSISENFLVNSSNLIPSPALNPINNNNNSNNNNNNIGDIKKINLEISQIPSTNLNPKLSLVINNNNNNNNNNNSLLKTIITNAINNNINNSNNDDNSNNTTIPTPPSSAINMINSLPLPSPSPSFILPTLSPFSSPLSELKSSSNNNNNNNNNSNNNNNNSMSPNLRSPKANSNKNLLGGIQIMLVDDLEETTHLFSSMLYKLGAKRIDTFQRVSDAYAFLCDSSKPQPDIILSDLTMPFEDGYSMVRKLRDREKINTQNKKTPIIALTASVSSSDKEKVLKSGFDLHCSKPVNFLELSNSILTLIEKYNTTVNIDLIKEQEQNNNNNNNNNNNNNNNNNNNNNNINNGNDDDSLLLTDSRPCKKANSQ
Protein: Probable cyclic di-GMP phosphodiesterase PdeG (EC 3.1.4.52) (P75995)
Organism: Escherichia coli (strain K12)
Function: Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Note=Found associated with the RNA degradosome. {ECO:0000269|PubMed:16139413}.
Interaction partners:
- Diguanylate cyclase DgcP
- Diguanylate cyclase DgcM
- Probable diguanylate cyclase DgcC
- Diguanylate cyclase DgcN
- Diguanylate cyclase DosC
- Probable diguanylate cyclase DgcT
- Probable diguanylate cyclase CdgI
- Probable diguanylate cyclase DgcI
- Probable diguanylate cyclase DgcF
- Diguanylate cyclase DgcZ
Sequence:
MRNTLIPILVAICLFITGVAILNIQLWYSAKAEYLAGARYAANNINHILEEASQATQTAVNIAGKECNLEEQYQLGTEAALKPHLRTIIILKQGIVWCTSLPGNRVLLSRIPVFPDSNLLLAPAIDTVNRLPILLYQNQFADTRILVTISDQHIRGALNVPLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRLIDKGFGILIFILLIACAAAFLLDRYFNKSATPEEILRRAINNGEIVPFYQPVVNGREGTLRGVEVLARWKQPHGGYISPAAFIPLAEKSGLIVPLTQSLMNQVARQMNAIASKLPEGFHIGINFSASHIISPTFVDECLNFRDSFTRRDLNLVLEVTEREPLNVDESLVQRLNILHENGFVIALDDFGTGYSGLSYLHDLHIDYIKIDHSFVGRVNADPESTRILDCVLDLARKLSISIVAEGVETKEQLDYLNQNYITFQQGYYFYKPVTYIDLVKIILSKPKVKVVVE
Protein: Potassium/proton antiporter CemA (Chloroplast envelope membrane protein A) (CemA) (Q6ENG1)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01308}.
Interaction partners:
- Photosystem II reaction center protein Z
- Photosystem I assembly protein Ycf4
Sequence:
MKKKKALPSFLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSQTLLTAIQEKRVLERFMELEDLFILDEMIKEKPNTHVQNPPIGIRKEIIQLAKIDNEGHLHIILHFSTNIICLAILSGSFFLGKEELVILNSWVQEFFYNLNDSVKAFFILLVTDFFVGFHSTRGWELLIRWVYNDLGWVPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
Protein: H/ACA ribonucleoprotein complex subunit (Q57US8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU364004}.
Interaction partners:
- 50S ribosomal protein L7Ae, putative
- Centromere/microtubule binding protein cbf5, putative
- Nucleolar protein 10
- Nucleolar RNA binding protein, putative
- Guanine nucleotide-binding protein subunit beta-like protein
- H/ACA ribonucleoprotein complex subunit 2
- Nucleolar protein 56
- rRNA 2'-O-methyltransferase fibrillarin
- Fibrillarin, putative
- Fibrillarin, putative
Sequence:
MARGGGGFGGSRGGGFGGGRGGGGRGGGFGGGFGGGRGGGGRGGGGGGGRSMEPDPPEQIVPIGTLLTASEGDLVYKVTASDSVPRFNAFVYGANKAKIGKIEEILGNTSDVMFSVKTVPGIQAESISAGDTIYISPTQISPLRMFTDPPKPRGRGGRGGGRGGRGGDRGGRGSFGRGGRGSFGGGGGGGGGGRGGFGRGGDGGGYRNFGGGGGGRGGRGGFGGRGRGF
Protein: C-type lectin domain family 9 member A (CD antigen CD370) (Q6UXN8)
Organism: Homo sapiens (Human)
Function: Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Subcellular location: Membrane {ECO:0000269|PubMed:18408006}; Single-pass type II membrane protein {ECO:0000269|PubMed:18408006}.
Interaction partners:
- Thrombomodulin
- Metallophosphoesterase 1
- Tyrosine-protein kinase SYK
- Chemokine XC receptor 1
- Lymphocyte antigen 75
- Basic leucine zipper transcriptional factor ATF-like 3
- T-cell surface glycoprotein CD1c
- Interferon regulatory factor 8
- C-type lectin domain family 4 member D
Sequence:
MHEEEIYTSLQWDSPAPDTYQKCLSSNKCSGACCLVMVISCVFCMGLLTASIFLGVKLLQVSTIAMQQQEKLIQQERALLNFTEWKRSCALQMKYCQAFMQNSLSSAHNSSPCPNNWIQNRESCYYVSEIWSIWHTSQENCLKEGSTLLQIESKEEMDFITGSLRKIKGSYDYWVGLSQDGHSGRWLWQDGSSPSPGLLPAERSQSANQVCGYVKSNSLLSSNCSTWKYFICEKYALRSSV
Protein: Translation initiation factor eIF2B subunit beta (eIF2B GDP-GTP exchange factor subunit beta) (Q53XC2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
Sequence:
MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL
Protein: C-CAP/cofactor C-like domain-containing protein (Q386R6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTNKYAPGNPYYGDSSPTSALLGTNQVVFCVNSVLFQSCGLLLEVPSGLTTSSVMKIRQECPNRTAISLSVWVDIAINVLGMRESVASSIFDVVYALTGGYTQYTAASLGSSTGSGNGSPEVRSPVECRQEESRSLLKKMGGTVDVARWPVVSATRQIGLPALIIFLLAQLVVEQTQRVLPGESERERVMASVRQHLHDYISVVAITRPGRLTLSDSKELRILLREFVNGVEQPFGTSIGFLWPRSEKTIDITILSQFIRPRITVPSELAATSRSSPFSNNIVVKGLQGTICIPTCPVVTYSPKLAISSSYTVEKCSQTSFYVTSDLPHTRLTQLVNCTVALGPVGGVLYIDRCENTNISALCTAVVVNRCRNVNIFICTNSPPVLCQLEGSENSENVRFAPYNSHYSTLEEHLANSGVNPMMNLWNVGIPSPHCILPPDEFTPVCFPVAPHTSAVVTTRTNPCPPPPPYATAMERRVRRFQETSRQLREAYERLEADGRKDLADELRGKVHTLFVDWLRRVGQERVLASLLRKNANGQS
Protein: Uncharacterized protein C4H3.14c (Q10221)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Uncharacterized protein P8B7.02
- Myosin-51
Sequence:
MGLEGSEKLEHEIEQVHDNIENRKEEVSTLQDMANDLEKLTDHIEATYIGRGVPHDHAKTGSRKPSSGQLIATMQNEIDRLKKEGDKVSILLMQERKKRKELESAKNNLLNVYDSLKMQKASVSSMVNRKQRAAKEEQKIQEEFERQITDLLEEQQQLKLEIERLEAETERANSETEQYEKQKEALEEEYEELRNECLKHDPQLDAEIRTLQDTFEEVERTLTKQVSDAKIADKPLKDSMFNSNSEKEKIMHALEKAEKDADIYSEFIQQYMEQLESSLEKSSTAIENAQNRLAEMTAHLAESSDYDNDDDTDGIINETDYELDTSQSEFATLTTSSNKSILNES
Protein: E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Q561U2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|PIRNR:PIRNR037880}.
Interaction partners:
Sequence:
MIVFVRFNSSHGFPVELEQGASVSELKEAVGRLQGVQSDQLRVIFAGRELCNESTLQGCDLPEQSTVHVVLPPSTSAHRSELIQQRRLGSGMESLTRLDLSSSRQTTASEGLAVILETEASRREDTAGHTGAKAHSSFYVFCKTVCKAIQPGKLRVRCKDCKQGTLTLSRGPSCWDDVLLPNRIHGVCQSQGCNGRLAEFYLKCASHPTCDNDTSVALDLIMPNTRRVPCIACTDIMTPVLVFQCAERHVICLECFHLYCVSRLNERQFTQETLLGYSLPCAAGCPDSLIKEVHHFRVLGEEQYERYQRYAAEECVLQMGGVLCPAPGCGAGLLPPDEERRVCCEPGNNGLGCGFVFCRDCKEEFHEGPCRHTTSTASAGALQGYVVDEEAALRARWEQASQETITKTTHPCPKCQVPVEKNGGCMHMVCPRPQCKFEWCWLCRVEWNRDCMGNHWFE
Protein: Cilia- and flagella-associated protein 221 (Primary ciliary dyskinesia protein 1) (A9Q751)
Organism: Mus musculus (Mouse)
Function: May play a role in cilium morphogenesis.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:18039845}. Cytoplasm {ECO:0000269|PubMed:18039845, ECO:0000269|PubMed:29690537}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:29690537}. Note=Localizes to the manchette in elongating spermatids in a SPAG17-dependent manner. {ECO:0000269|PubMed:29690537}.
Interaction partners:
- Actin-related protein 6
- RuvB-like 1
- RuvB-like 2
- Vacuolar protein sorting-associated protein 72 homolog
- YEATS domain-containing protein 4
- DNA methyltransferase 1-associated protein 1
Sequence:
MEVVKSPMQELQQAKEPFDTMSPLLLKSLVEEPKKRTEVPNHLLESRVYAKLLNNKVIQARPGIVHFGGYEIESKHQQILNIANISDEDTHLHILPPQTKYFQINFEKKEHRLIPGLSLTVTITFSPDEWRYYYDCIRIHCKGDDTLLVPIHAYPVLNNLDFPTFINLSDVFLGESKSYVIPLQCSCPVDFEFHITLLRSHQAFTIEPKSGIIPANGKAKVTVKFTPIQYGMAQIKIQLWISQFNSQPYECVFTGTCYPNMALPLEEFKRLNTRSKKVNVPLEKTTYVQFYPAPAKAKPQKLKEIDYQDLRFPADLSNPFAVATVLNQEPGKLKIKELKQVLDQGDEISKTRQMKEAIFEQKVRQDILTEIENHLKWQVHLGKEHTTYRFKRELTEEWKKARAKYKQNRGDPVEGEELQRLQTEQSQKRIVRDLKGKRQEFHPNFDPLVNNVWLTRHRAQRRFQQAARKIMLERRLLSMLGAIRGMDKESILRKIIQVNGKLIQGENPSRGRRAHLKQEDNIWRYSLESEEVLHFAFPTDSESYNELALDGLGLVPIKSPEIQIKHSYPYFTLKVPQLYKIKGYHPFSVNKSSTNYRLQKLARPLKHGAEDEVTTIITIPKKDTTPLSAKPSILSMKPPEGLAMSVEYDPLYIFNPSPGLFAVKHPLTYAETLIDYHLCSHPKYKYTQESHMGSSIPLTQRQFLHHTDIIPGIMNWKKFQPLVFSSMSDPSMVEATQRSDWYSSVMLPIDVPAPLEDLPEEDRLETTERDLCDQGIEVMLTPEMVQVEFPMLIHRDSKKEKDFKDSTQLPEKVGERVQEEMKNLRSKALNTYLILD
Protein: Plant UBX domain-containing protein 4 (PUX4) (CDC48-interacting UBX-domain protein 4) (Q8RWU7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Cell division control protein 48 homolog A
- Plant UBX domain-containing protein 2
- F13M7.16 protein
- Plant UBX domain-containing protein 3
- Plant UBX domain-containing protein 11
- Plant UBX domain-containing protein 5
- AT3g18860/MCB22_3
- Cell division control protein 48 homolog E
- Cell division control protein 48 homolog D
- OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 2
Sequence:
MSSKDKKPSKPSSSRGGIRTLSDLNRRSGPDSDSDSDGPQEYYTGGEKSGMLVQDPSKKDDVDEIFNQARQLGAVEGPLEPPPSSRSFTGTGRLLSGENVPTGNQQPEPVVHNIVFWSNGFTIDDGPLRKLDDPENASFLESIRKSECPKELEPADRRAPVHVNLMRKEEKCPERQKRRVSFQGVGRTLGGSNEGSGSSSPVAPDSAPIPIQTEPAPSQSLVIDETVPTTSIQLRLADGTRLVAKFNHHHTVNDIRGFIDSSRPGASLNYQLQTMGFPPKPLTDLTQTIEEAGLANSVVLQKF
Protein: Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme N) (Protein bendless) (Ubiquitin carrier protein N) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase D3) (Ubiquitin-protein ligase N) (P35128)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the covalent attachment of ubiquitin to other proteins.
Interaction partners:
- GEO06356p1
- GH01161p
- E1 ubiquitin-activating enzyme
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-ribosomal protein eL40 fusion protein
- Mitogen-activated protein kinase kinase kinase 7
- Death-associated inhibitor of apoptosis 2
- E3 ubiquitin-protein ligase CHIP
- Ubiquitin thioesterase otubain-like
- AT16033p
Sequence:
MSSLPRRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTGPNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNIDRLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED
Protein: Large ribosomal subunit protein uL23cz/uL23cy (50S ribosomal protein L23, chloroplastic) (P61845)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to 23S rRNA.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL2cz/uL2cy
- Small ribosomal subunit protein uS19c
- Small ribosomal subunit protein uS7cz/uS7cy
- Chloroplastic ATP-dependent Clp protease proteolytic subunit 1
- Protein TIC 214
- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- NAD
- Protein Ycf2
- Small ribosomal subunit protein bS16cz
- Small ribosomal subunit protein uS7m
Sequence:
MDGIKYAVFTDKSIRLLGKNQYTFNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKVKRMGPILGHTMHYRRMIITLQPGYSIPPLRKKRT
Protein: RE23355p (Q8IGV5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSQHNYTNPAFCQNSEYYPVPSGNSSRVESIYNRSLQMNFGAAPPRATRDPREGPLRMQRSMSTRSVTRKQHQQQQQQQHQQQIHQQHLAQQQQHQPQSSSGRYALVPLEELNSSRASRYAIVPGQAAQRLARSQDNLDRYGSRHGLHEEEEPHSFHEEPHQETQFASLPPILNLPPKPRNINNNTNANQTQIKHAFSSDFGSKTFLIVDKNSNQRYQMVPTAEDEELVDENQEIIQMHNGRAHRYAVVPTDADDDDLAEEQEQQETCLSNMELSRQYAARTSTPQQKDAAAATRALHELLTTPRKMQPPPRLAHSTPRNAAHHEQLQLERRLEIYKSQQIYQSQQVGAVVGVPPTLPLRQNRLSPQRLHYETVKPLPMQIADRSMAVISPRVQEQGQEQEREQDMSSIQGKGKKNSSYPQKMANATITLAVVSLMLVLGSTMNAGLIIYMIAHLGKSFYLQFSLVASFSGMGLGFLGFKSRHCEWLPNRSYSSGYILVTVFCLFKSCGLLVILVVDPFPGFPVHDVTTGVILGLSTFTMFFIGLGVLGSLWCHRPPPDNRVNVV
Protein: Peroxisomal ATPase PEX1 (Peroxin-1) (A0A0C4DG33)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MWGSDRLAGAGGGGAAVTVAFTNARDCFLHLPRRLVAQLHLLQNQAIEVVWSHQPAFLSWVEGRHFSDQGENVAEINRQVGQKLGLSNGGQVFLKPCSHVVSCQQVEVEPLSADDWEILELHAVSLEQHLLDQIRIVFPKAIFPVWVDQQTYIFIQIVALIPAASYGRLETDTKLLIQPKTRRAKENTFSKADAEYKKLHSYGRDQKGMMKELQTKQLQSNTVGITESNENESEIPVDSSSVASLWTMIGSIFSFQSEKKQETSWGLTEINAFKNMQSKVVPLDNIFRVCKSQPPSIYNASATSVFHKHCAIHVFPWDQEYFDVEPSFTVTYGKLVKLLSPKQQQSKTKQNVLSPEKEKQMSEPLDQKKIRSDHNEEDEKACVLQVVWNGLEELNNAIKYTKNVEVLHLGKVWIPDDLRKRLNIEMHAVVRITPVEVTPKIPRSLKLQPRENLPKDISEEDIKTVFYSWLQQSTTTMLPLVISEEEFIKLETKDGLKEFSLSIVHSWEKEKDKNIFLLSPNLLQKTTIQVLLDPMVKEENSEEIDFILPFLKLSSLGGVNSLGVSSLEHITHSLLGRPLSRQLMSLVAGLRNGALLLTGGKGSGKSTLAKAICKEAFDKLDAHVERVDCKALRALNDMIKEFISMGSLVALIATSQSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNVIKNKLDCDINKFTDLDLQHVAKETGGFVARDFTVLVDRAIHSRLSRQSISTREKLVLTTLDFQKALRGFLPASLRSVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGMLLSSGLQDGSSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLDQSLVSLEMSEILPDESKFNMYRLYFGSSYESELGNGTSSDLSSQCLSAPSSMTQDLPGVPGKDQLFSQPPVLRTASQEGCQELTQEQRDQLRADISIIKGRYRSQSGEDESMNQPGPIKTRLAISQSHLMTALGHTRPSISEDDWKNFAELYESFQNPKRRKNQSGTMFRPGQKVTLA
Protein: Uncharacterized protein At3g14900 (Q9LKB4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Embryo defective 1703
- Ubiquitin carboxyl-terminal hydrolase family protein
- Pentatricopeptide repeat-containing protein At5g50280, chloroplastic
- Small ribosomal subunit biogenesis GTPase RsgA 1, mitochondrial
- Large ribosomal subunit protein uL13x
- Telomere repeat-binding factor 5
- DNA-binding protein S1FA3
- 1,4-alpha-glucan-branching enzyme 3, chloroplastic/amyloplastic
Sequence:
MLSQDLSFSKTLNPSFSFRKSPLNSGVRRIVSVLPAITERNYAFSVKRSELLLREDGGFRRDVRALAGRSKKKLGGGSSGGRIEGDSDMRKQVKRNAREKSKKLAESLFYRLYNNPDKSRSQILSSHPDKFTEEELEMIGLGYDRMVRFMDKDDPRLRHPYDWFKYGEFGPYSWRGVVVGDPVRGTISDECVTMIGEVENHEEFEKIEQHEMNIAFQKRVKELDSNVGLRYFWVFVRHPKWRLSELPWEQWTLVSEVVVEADKKQRLDKWNLMGRLGNKSRSLICQCAAWFRPDIVYVKKPVFQCRFEPQEDFFNSLIPYLNPVTESGFVCEVEDDEGRVELSTYYGGLCKMLKVRQTAFVDDVVNAYEKLSDEKKSRVLKFLLGNHPNELLHPYTKEWKAKLEEMELGCDAPDEDEDEISISGSSEKAEFSEWIEDEADNDDDDDDDDDDDGEVEEVDDDDNMVVDVEGNVEEDSLEDEIEESDPEEDERYWEEQFNKATNNAERMEKLAEMSMVVSDKFYEKQLKALEEREKGEIEGDELEMRGKKAKVKPEEWKTVGYGRWMKKIKKSRIPPELFLRAAVRPFVYRNLVKEIVLTRHAILEGEIGQKE