wanglab/gogpt-training-data huggingface dataset:
Protein: Kinesin light chain (Q91YS4)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367020}.
Interaction partners:
Sequence:
MATMVLPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLASHEAGEAEPGSQERCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDSLDDLFPNEDEQSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRSRKQGLDPASQTKVVELLKDGSGGRGHRRGSRDVAGPQSESDLEESGPAAEWSGDGSGSLRRSGSFGKLRDALRRSSEMLVRKLQGGGPQEPPNSRMKRASSLNFLNKSVEEPVQPGGTGLSDSRTLSSSSMDLSRRSSLVG
Protein: Thermoresistant gluconokinase (EC 2.7.1.12) (Gluconate kinase 2) (P46859)
Organism: Escherichia coli (strain K12)
Interaction partners:
- 6-phosphogluconate dehydrogenase, decarboxylating
- Phosphogluconate dehydratase
- Low-affinity gluconate transporter
- Glyoxylate/hydroxypyruvate reductase B
- Thermosensitive gluconokinase
- 6-phosphogluconolactonase
- Ribose-5-phosphate isomerase A
- High-affinity gluconate transporter
- HTH-type transcriptional regulator GntR
- KHG/KDPG aldolase
Sequence:
MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGNPNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPLEGVVASTIEVIKKGK
Protein: Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) (Q9Z2K1)
Organism: Mus musculus (Mouse)
Function: Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance.
Interaction partners:
- Keratin, type II cytoskeletal 6B
- Keratin, type II cytoskeletal 6A
- Keratin, type I cytoskeletal 14
- Keratin, type I cytoskeletal 17
- Protein S100-A15A
- Filaggrin
Sequence:
MATCSRQFTSSSSMKGSCGIGGGSSRMSSILAGGSCRAPSTCGGMSVTSSRFSSGGVCGIGGGYGGSFSSSSFGGGLGSGFGGRFDGFGGGFGAGLGGGLGGGIGDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLEVKIRDWYQRQRPTEIKDYSPYFKTIEDLKSKIIIATQENAQFTLQIDNARLAADDFRTKYENELFLRQSVEGDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDVEAWFLRKTEELNKEVASNSDLIQSNRSEVAELRRVFQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLISSVEEQLAQLRCEMEQQSQEYNILLDVKTRLEQEIATYRRLLDGENIHSSSQHSSGQSYSSREVFSSSSRQPRSILKEQGSTSFSQSQSQSSRD
Protein: Rodlet protein (P28346)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures. Important for the formation of hydrophobic rodlet layers of asexually-produced spores.
Subcellular location: Secreted, cell wall.
Interaction partners:
- Class I hydrophobin dewA
Sequence:
MKFSIAAAVVAFAASVAALPPAHDSQFAGNGVGNKGNSNVKFPVPENVTVKQASDKCGDQAQLSCCNKATYAGDTTTVDEGLLSGALSGLIGAGSGAEGLGLFDQCSKLDVAVLIGIQDLVNQKCKQNIACCQNSPSSADGNLIGVGLPCVALGSIL
Protein: ATP-dependent RNA helicase (EC 3.6.4.13) (Q38C70)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Pescadillo homolog
Sequence:
MNIYSWESSARPQKGKAKKAGTIVFHPDETVDLSFNRLQKEYPLDKTEHPNSQKASEGQTERKKAPLMTAGTAKNLVKRMGFEALLPCQAQCYRGVFNRRDVILHSRTGSGKTLAYALPIIERHLIMSSFSPPASTGPFLLIFLFSNELAAQTKGVLKKIYPKLNILIAGFDNLEVRRCDVLIGTVRSLDEAIRGRLSKESTRGEKRTRSGRAREEEEEKEEAYCDDPGTDEREGDFASSSVSASNVCAIVVDEVDLTLGPRFSNIGRRMRNLLNFIRKANGSLAKGLLTDYRAHHYVLCGATIPNWVVKAGFLGVKKYYYQLVTVGTAKLPERLECFSMYCPQKARVDRAVQLLSTGNFGRTVVFGTRKQVLKIESFLLTQNLQFSFSSLDPGKDEVERIKAMENFNSGAASVIFCTDLAARGLDFIDVHMVLMLSLPKHNMAVETFVHRAGRTARAGRPGKCLQLHDEREDAAIEVIEKNAHIVFKKYIVGGEGKGSVARKRIKKGNLTPPNDQAKTTFTLTVKNPFRSTKPDAVVPTALDVLKKNIGSLFSNVCNVTEDVSGEIVTFEYPANSSHEVRQKLWKFSLKEVTPQN
Protein: Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) (Endothelial ligand FOR L-selectin) (MC26) (SGP50) (Sulfated 50 kDa glycoprotein) (Q02596)
Organism: Mus musculus (Mouse)
Function: Adhesion molecule that accomplishes cell binding by presenting carbohydrate(s) to the lectin domain of L-selectin.
Subcellular location: Cell membrane.
Interaction partners:
- L-selectin
- E-selectin
- Alpha-S2-casein-like B
- Mucosal addressin cell adhesion molecule 1
- Beta-casein
- CMRF35-like molecule 9
- Alpha-lactalbumin
- Podocalyxin
- Carbohydrate sulfotransferase 4
- Endomucin
Sequence:
MKFFTVLLFVSLAATSLALLPGSKDELQMKTQPTDAIPAAQSTPTSYTSEESTSSKDLSKEPSIFREELISKDNVVIESTKPENQEAQDGLRSGSSQLEETTRPTTSAATTSEENLTKSSQTVEEELGKIIEGFVTGAEDIISGASRITKS
Protein: F-box-like/WD repeat-containing protein TBL1X (Transducin beta-like protein 1X) (Q9QXE7)
Organism: Mus musculus (Mouse)
Function: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Note=Colocalized with MECP2 to the heterochromatin foci. {ECO:0000269|PubMed:28348241}.
Interaction partners:
- F-box-like/WD repeat-containing protein TBL1XR1
- Nuclear receptor corepressor 1
- G protein pathway suppressor 2
- Nuclear receptor corepressor 2
- Catenin beta-1
- Histone deacetylase 3
- S-phase kinase-associated protein 1
- Adenomatous polyposis coli protein
- Adenomatous polyposis coli protein 2
- Histone deacetylase 1
Sequence:
MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQANAAAAAAAAAATATSTAATTPAAAAQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Protein: SR-CI (Q5ELV0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEFFWTLAVIVIYCIGHIHGRCERSIDLDNGSINYRQRNVVRFRCNRGYTLQGTVMQTCDRDGRLRGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGAYGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGTNGFSTTTEPTAPTGSNEQPLVYDMMSCSGRCGTSMSASNITNNGIVMGCGCNDECLSDETCCLNYLEECTKELLTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTTTSTTTTKRPTTTTTTTKATTTKRTTTTKKPTTTSTTPKPTTTTSTTPKSTTSTTSTTSTTPTTTTTINVFTTKKTTIMIPTSSTEKTTGIITTMKTRKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLGIVLVVVLANVVNRWIIPITGSKTSSEKAVRFKKAFDSLKKQRKRNSMDDQPLCDSDNDDVEYFEEMGVDIRHRTDL
Protein: Abscisic acid receptor PYL10 (PYR1-like protein 1) (OsPYL1) (PYR1-like protein 10) (OsPYL10) (Regulatory components of ABA receptor 10) (Q7XBY6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Inhibits the protein phosphatases PP2C06 and PP2C09 when activated by abscisic acid (ABA). Together with PP2C53, SAPK8 and SAPK10, may form an ABA signaling module involved in stress response.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:26362328, ECO:0000269|PubMed:26491145}. Nucleus {ECO:0000269|PubMed:26362328, ECO:0000269|PubMed:26491145}.
Interaction partners:
- Protein phosphatase 2C 53
- Probable protein phosphatase 2C 6
- Protein phosphatase 2C 50
- protein-serine/threonine phosphatase
- Probable protein phosphatase 2C 30
- Probable protein phosphatase 2C 49
- Probable protein phosphatase 2C 68
- Probable protein phosphatase 2C 9
- protein-serine/threonine phosphatase
- Probable protein phosphatase 2C 37
Sequence:
MEQQEEVPPPPAGLGLTAEEYAQVRATVEAHHRYAVGPGQCSSLLAQRIHAPPAAVWAVVRRFDCPQVYKHFIRSCVLRPDPHHDDNGNDLRPGRLREVSVISGLPASTSTERLDLLDDAHRVFGFTITGGEHRLRNYRSVTTVSQLDEICTLVLESYIVDVPDGNTEDDTRLFADTVIRLNLQKLKSVSEANANAAAAAAAPPPPPPAAAE
Protein: Recoverin (23 kDa photoreceptor cell-specific protein) (Cancer-associated retinopathy protein) (Protein CAR) (P34057)
Organism: Mus musculus (Mouse)
Function: Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells (By similarity). Modulates light sensitivity of cone photoreceptor in dark and dim conditions. In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin (By similarity). Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells. Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light.
Subcellular location: Photoreceptor inner segment {ECO:0000269|PubMed:15882641, ECO:0000269|PubMed:15961391, ECO:0000269|PubMed:28151698}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:15882641, ECO:0000269|PubMed:15961391, ECO:0000269|PubMed:28151698}. Photoreceptor outer segment membrane {ECO:0000250|UniProtKB:P21457}; Lipid-anchor {ECO:0000250|UniProtKB:P21457}; Cytoplasmic side {ECO:0000250|UniProtKB:P21457}. Perikaryon {ECO:0000269|PubMed:28151698}. Note=Primarily expressed in the inner segments of light-adapted rod photoreceptors, approximately 10% of which translocates from photoreceptor outer segments upon light stimulation (PubMed:15961391). Targeting of myristoylated protein to rod photoreceptor outer segments is calcium dependent (By similarity). {ECO:0000250|UniProtKB:P21457, ECO:0000269|PubMed:15961391}.
Interaction partners:
- Rhodopsin kinase GRK1
- Rhodopsin
- Cone-rod homeobox protein
- Arrestin-C
- Guanine nucleotide-binding protein G
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
- Aryl-hydrocarbon-interacting protein-like 1
- S-arrestin
- Visual system homeobox 2
- Photoreceptor-specific nuclear receptor
Sequence:
MGNSKSGALSKEILEELQLNTKFTEEELSAWYQSFLKECPSGRITRQEFESIYSKFFPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMIKPEDVKLLPDDENTPEKRAEKIWAFFGKKEDDKLTEEEFIEGTLANKEILRLIQFEPQKVKERIKEKKQ
Protein: DSC E3 ubiquitin ligase complex subunit A (EC 2.3.2.27) (Defective for SREBP cleavage protein A) (RING-type E3 ubiquitin transferase dscA) (E9QSG0)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:23104569}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- DSC E3 ubiquitin ligase complex subunit B
- UBX domain protein
Sequence:
MDNRGSFFFLLIVFYLLLSSQSRPPLLDQDRERQREVARERDALRLLNESKYGDFDPPGDKWLPFAGTRKNDSYAWGILPEAQGRARHQLRSAISNAGLEPPRSLEDPDALPSLNLTQLLLPVYRNATGKLRGDWVRRKLNKEYPKLNTTAIALEHGYFTHEFGLNITGSSGTFYLDLREGGGEELRVDSGQVREIRATLAVESNDFWGNTWYISLFGVHFPETGAIILSSNSEKFEGLFVLPHLAFSSDAYELSHQLLLNSLSDTLSEKENRPPTLFPWSSLIGSEQVEFPAPKCEHIIYLQQHPVTIHDYLADKPVVDQIEEELRFPIGAPVPPAPLMVMSAVVFSPDCGYILETKGTPDFPPSEGLYLTGPKIEEYDKYSARLVFIICGVFAAQITLLLRQIKEASTPSTRSRISFYTIALMAFGDAFVLIFILLELYPAVSFLVMATAAFLTFLSVSYIGMKFMMEIWAVQAPERREQERRSNPPASTPRSTGLPLPATSAPVRDSGATPIILTPDQDPPAEEDDQPTNRGTTSAAQETRNDVGAMYARFYFVLFVMLIISIWSFLWPNRLGALYARALAFVYLSFWTPQIGRNIIRNCRKALRWDFVIGQSILRLFPFVYFLTVRGNVLFIHPDTTTAFALAGWVWIQVWVLASQDILGPRFFVPRGWAPAAYDYHPILRDGDESEADLESGGVLPIGALRAEDLSGDAKDEDKQRTKDRKRAVFDCAICMQEIEVPVLAARGSAGGSSVTEGATSILSRRTYMVTPCRHIFHSTCLESWMRLRLQCPICRESIPPV
Protein: Rho GTPase activating protein at 71E, isoform G (M9PFL1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSWAERVHRRAADLGNVVTSCGHPATAPAYPYRLEKVKFGVPLEEVCKHNNNIPGPLLVLILKLNKESPNRRDVFRAPGHQGAMKKLIHFLQAGRLVNVDNYSVFTIASVLKKFLRKIPNGIFGRSGEMELFAINDLQNEAEQTERLHRLFGSLPKYTQHLLVLLFGTFRVIASNAAHASTGMTSEALGVSVAPSFFQSCVSDGKTARMEDVLKFKVSTKIMQNIIDKFATHDIFGRDNYEYYARVTGRILKVQDEWICSFQYPPPPRGKLAQQKYALQHSLEAEKTWLQCQCERWGLLGNIRLSNSAESIQYAARRPVASLGLNPSLGGAITTINTTSTHNPTTRRLLINVPRQYRSSLRRNKEKQIGGNSQSNSSNSLGSDQLTGNAGAAAGSAVGVPVLNKPLLMVGLLPGAEQPPSVRNSIAECGISTPDAMDVGMECSTTLSFKPPRL
Protein: Stomatin (Erythrocyte band 7 integral membrane protein) (Erythrocyte membrane protein band 7.2) (Protein 7.2b) (P27105)
Organism: Homo sapiens (Human)
Function: Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:9243190}; Peripheral membrane protein {ECO:0000269|PubMed:9243190}; Cytoplasmic side {ECO:0000269|PubMed:9243190}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9243190}. Cell membrane {ECO:0000269|PubMed:12130500}; Lipid-anchor {ECO:0000269|PubMed:12130500}; Cytoplasmic side {ECO:0000269|PubMed:12130500}. Membrane raft {ECO:0000269|PubMed:12130500, ECO:0000269|PubMed:23219802}. Melanosome {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P54116}. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190). Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). {ECO:0000269|PubMed:12130500, ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:9243190}.
Interaction partners:
- Prohibitin 1
- Flotillin-1
- Acid-sensing ion channel 2
- Solute carrier family 2, facilitated glucose transporter member 1
- Flotillin-2
- Acid-sensing ion channel 3
- Glutathione S-transferase LANCL1
- Caveolin-1
- Acid-sensing ion channel 1
- ATP-dependent zinc metalloprotease YME1L1
Sequence:
MAEKRHTRDSEAQRLPDSFKDSPSKGLGPCGWILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIIGAKHSHLG
Protein: Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52) (Q9Y2R4)
Organism: Homo sapiens (Human)
Function: Required for efficient ribosome biogenesis (By similarity). May control cell cycle progression by regulating translation of mRNAs that contain a terminal oligo pyrimidine (TOP) motif in their 5' UTRs, such as GTPBP4 (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
Interaction partners:
- Something about silencing protein 10
- Protein RRP5 homolog
- KRR1 small subunit processome component homolog
- Nucleolar protein 6
- Nucleolar protein 14
- Protein AATF
- WD repeat-containing protein 46
- Probable ATP-dependent RNA helicase DDX47
- Small subunit processome component 20 homolog
- Probable ATP-dependent RNA helicase DDX49
Sequence:
MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAVRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS
Protein: Zinc-regulated protein 8 (Q6FWW3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Involved in maintenance of polarized growth and daughter-cell-specific transcription.
Subcellular location: Cytoplasm {ECO:0000250}. Bud {ECO:0000250}. Bud neck {ECO:0000250}. Bud tip {ECO:0000250}.
Interaction partners:
Sequence:
MRSFIKSHRKSNSLESDSDIDFKQLKRKNASTSQLSPPRYNTDYYDPVTSSPKTPTHSHTTSDSLPQKHSPGFESLHRLFNNKLFKKASNSSLNSYLANTDSQSRRSSKDQDPLAPSFHVLKTSSNPASQDSELPVIKGVITHTWGNHSKHNDPHVIVLNDPKTSFETLRSSDLEPPPRLTSKTTRSSVSSERSWSTRDHSMSPPLTSINQDIDIPEDMATRSKNTLINKKKMENRQARIHSNDDLIAMRKNSSDTLPQTAEFFASDKLPGDSTPILEIPESPPPVITLEKYNSSLSDAKELSRSKNVRSNRTSVVSMTQSEESRWSNHLMVNSNHNQNKLRDSDDSDYSNAIDEEDDDDADDDDEASQFSFEYSNLSGRTPSVKYYSKPEPKQMVYIDDLYDDEDFDEDMNYYDENEVSEFLQEEMASNKNNINTDTSVLKDLSSPSINDHSNEKPIYKPTIQMRVNKPKVHRYNDLFALSDEDDPSFNDDDEFDEDEEEGGDDNDEEDEIDEEYDQKVSDECGQSIELQSDDIHSDYGVEYYNDFGGDLNLQNDVQKHHINKEQQYISDEEFDDAITDFNMAKHIIEEEVVLDKAEALRYQKDAEPVQSKTSEDVVNYVDEDSNLRINEKLEKGDVTYQKPTLLTEVKNKQFQKKPVASFADIFNLESDSEEDINNEDGLTGLSDVGLDEDDAVSSPILQSPFESQSLAEGLVSPVICTPGKPNIINKQIIPTIKCEPSSPQEKTIENNKSHTASNFKEYGLNHPLPPPARSQALKFHDLNSELDSELPALMSNLYFIDETEEDAYNELNDVTRDEDEYLDEINTVPEDFNFSDTENDNNAAKRMLRRSNKGSFRSTYSFTDKPQGVTTESSPIKNKLEVNNKTVTFFSSPGWSKSPGSEIGMQRSKSPVKPSSGYRPFGQGSKQFPITPSHEPNYSIEEDRIASTDEILESRTPPTTYMAPSPAFIPNYSLSPIQEASSSVTNSPKR
Protein: G-substrate (Protein phosphatase 1 regulatory subunit 17) (Q6X855)
Organism: Oryctolagus cuniculus (Rabbit)
Interaction partners:
Sequence:
MMSMEQMQPLEFSEDRLDTLDPCSNHLDDLSDQFIKDCDLKKPRKGKNGQTTLNVESDQKKPRRKDTPALHIPPFIPGVISENSIRRYDLQERHPKGKVDPDLHNTDLEQQKPRRKDTPALHTSPFESGVRPLRDERPKVIVEDDEKEGDKIAI
Protein: Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (POR1) (P53365)
Organism: Homo sapiens (Human)
Function: Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:22981988}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:21239483, ECO:0000269|PubMed:22679020, ECO:0000269|PubMed:26507660, ECO:0000269|PubMed:30917996, ECO:0000269|PubMed:31204568}.
Interaction partners:
- Ras-related C3 botulinum toxin substrate 1
- ADP-ribosylation factor-like protein 1
- ADP-ribosylation factor 1
- ADP-ribosylation factor 6
- ADP-ribosylation factor 5
- Cyclin-dependent kinase inhibitor 2A
- ADP-ribosylation factor 3
- Arfaptin-1
Sequence:
MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ
Protein: Endonuclease 2 (AtENDO2) (EC 3.1.30.1) (Deoxyribonuclease ENDO2) (Single-stranded-nucleate endonuclease ENDO2) (Q9C9G4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Endonuclease mostly active on RNA and ssDNA, and to a lower extent, on dsDNA. Can cleave mismatch regions in heteroduplex DNA containing single base pair mismatches or insertion/deletion bases. In contradiction with PubMed:22506810, cannot hydrolyze single-stranded DNA and does not cleave mismatches.
Interaction partners:
- DNA-
- Adenine DNA glycosylase
- At1g80850
- Bifunctional nuclease 1
Sequence:
MANQKGLHVVMMIITVWLLYAAPNIHGWGKEGHEIICKIAQTRLDETAAKAVKELLPESAEGDLSSLCLWADRVKFRYHWSSPLHYINTPDACSYQYNRDCKDESGEKGRCVAGAIYNYTTQLLSYKTAASSQSQYNLTEALLFVSHFMGDIHQPLHVSYASDKGGNTIEVHWYTRKANLHHIWDSNIIETAEADLYNSALEGMVDALKKNITTEWADQVKRWETCTKKTACPDIYASEGIQAACDWAYKGVTEGDTLEDEYFYSRLPIVYQRLAQGGVRLAATLNRIFG
Protein: Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 5 (AthCYSTM5) (Q1PEX8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in resistance to abiotic stress.
Subcellular location: Cell membrane {ECO:0000269|PubMed:29272523}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000269|PubMed:29272523}.
Interaction partners:
Sequence:
MSQYSQNQYAGAYPTPPVSTGPYVAPPPLGYPTNDTTHATVAPVETKSKGEAADGFLKGCLATMLACCVLDACIF
Protein: E3 ubiquitin-protein ligase ICP0 (EC 2.3.2.27) (IER 2.9/ER2.6) (P135 protein) (RING-type E3 ubiquitin transferase ICP0) (P29128)
Organism: Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)
Function: Evades nuclear antiviral defenses triggered by dsDNA viruses. Acts during the initial stages of lytic infection and the reactivation of latent viral genome. Prevents the antiviral effect of nuclear bodies by degrading host PML and SP100.
Interaction partners:
Sequence:
MAPPAAAPELGSCCICLDAITGAARALPCLHAFCLACIRRWLEGRPTCPLCKAPVQSLIHSVASDECFEEIPVGGGPGADGALEPDAAVIWGEDYDAGPIDLTAADGEASGAGGEAGAADGSEAGGGAGGAEEAGEARGAGAGRAAGAAGGRAGRGADAAQEFIDRVARGPRLPLLPNTPEHGPGAPYLRRVVEWVEGALVGSFAVTARELAAMTDYVMAMLAECGFDDDGLADAMEPLIGEDDAPAFVRSLLFVAARCVTVGPSHLIPQQSAPPGGRGVVFLDTSDSDSEGSEDDSWSESEESSSGLSTSDLTAIDDTETEPETDAEVESRRTRGASGAARARRPAERQYVSTRGRQTPAVQPAPRSLARRPCGRAAAVSAPPSSRSRGGRRDPRLPAAPRAAPAAQARACSPEPREEGRGAGLGVAAGETAGWGAGSEEGRGERRARLLGEAGPPRVQARRRRRTELDRAPTPAPAPAPAPAPISTVIDLTANAPARPADPAPAAAPGPASAGAQIGTPAAAAAVTAAAAAPSVARSSAPSPAVTAAATSTAAAISTRAPTPSPAGRAPAADPRRAGAPALAGAARAEVGRNGNPGRERRPASAMARGDLDPGPESSAQKRRRTEMEVAAWVRESLLGTPRRSSAALAPQPGGRQGPSLAGLLGRCSGGSAWRQ
Protein: Endothelial transcription factor GATA-2b (GATA-binding protein 2b) (F1QD30)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Runt-related transcription factor
- Transcriptional activator Myb isoform 1
- Growth factor-independent 1A transcription repressor a.
Sequence:
MMDAPAEPRWMMHAHHSAMMGTSDSVSPHAGLGHHSSGYMEPGAPLLQPDEVDVFLSHLDSQGNPYYHTHGSRARMSYSQTHARLTGGSMCRPHLINTHGLPLLDNSKSTFSTAQHHGSWTVSHLGKAVLHSAGAESSNGLYAGTGAPASGPMPCLSMTQHCSAQLYCLPPTPPKDVSPDPACAAVRDAGKYHLHLVDGMKMECSSPIRSNPHLAQTTTPIPSYPDYSVAGAHEYPASVFHSRNLLGNMTTKCKSKNRAFSGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIRPKRRLSASRRAGTCCANCQTGTTTLWRRNANGEPVCNACGLYYKLHNVNRPLTMKKDGIQTRNRKMSGKSKKRRGEHFHQFDSCVHDKPSSFSHMANIHHPFNMTPQIQLHPAFSHSSLVTAIG