wanglab/gogpt-training-data huggingface dataset:
Protein: GREB1-like protein (B9EJV3)
Organism: Mus musculus (Mouse)
Function: Plays a major role in early metanephros and genital development.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGNSYAGQLKSARFEEALHNSIEASLRCSTAVPRPIFSQLYLDPDQHPFSTADVKPKVEDLDKDLVHPYTQNGSVDFSHNVAMNEMEDDEDEEEMSDSNSPPIPYSQKPAPEGSCTTDGFCQAGKDLRLVSLCMEQIDIPAGFLLVGAKSPNLPEHILVCAVDKRFLPDDHGKNALLGFSGNCIGCGERGFRYFTEFSNHINLKLTTQPKKQKHLKYYLVRTSQGVLSKGPLICWKECRSRQSSALCHSTKPISSVSSAVAPENGTANGYKAGFTVTEAANGTSGHGGKSSSCSSTPSRPGNYSLSPRPTFTSVDQANMFISGPPKKRHRGWYPGSPVSQSALVVPAPTVRPLSRTEPLLSTPVPQTPLTGILQPRPVLAGETVIVPENLLSNSGVRPVILIGYGTLPYFYGNVGDIVVSPLLVNCYKIPQLENKDLEQLGLTSTHLLSVENMILLTIQYLVRLGPDQIPLREEFEQIMLTAMQEFSVRERALPLGAPCAPMSPAQLPWLARLAASVSQDLVHVIVTQNSLAEGISETLRLLSEMKHYQRLPDYVVAICASKIRGNEFCVVVLGQHQSRALAESMLTTSEFLKEISYELITGKVSFLASHFKTTSLGDDLDKLLEKMQQRRGDSVVTPFNGDLDECVSPQEAAAMIPTQNLDVDNETFQIYQPQLTVARRLLSQVCAIADSGSQSLDLGHFSKVDFIIIVPRSEVLVQQTLQRVRQSGVLVDLGLEESGLAHQRAERYVVRLDNEIQSKFEVFMRRVKQNPYTLFVLVHDNSHVELTSVISGSLSHGEPTHGLADRVINCREVLEAFNLLVLQVSSFPYTLQTQQSRISSSNEVHWIQLDTMEDAGCEKLYFGLDEYSKSLQWGITSPLLRCDETFEKMVSTLLERYPRLHSMVVRCYLLIQQYSEALMALTTMASLRDHSTPETLSIMDDLITSPGKNKSGKGHMLVIRVPSVQLAMLAKERLQEVRDKLGLQYRFEIILGSPASELTVETHFVTRLKTWRGNDQDEWIPRTYQDLEGLPCIVILTGKDPLGETFPRSLKYCDLRLIDSSYLTRTALEQEVGLACCYVSKEVIRGPAAALDLSAKEAERVPASENDSEELLIDLERPQSNSSAVTGTSGSIMENGVSSSSTAGKPQQQLLTPTSSIRLDEGVSASTAVVGEILKQECDSLDPPMASSTTSKPSSSSSSSAQALAWSRQPRGLHTALPPVIILSKAAYSLLGSQKGGRLPSSSSLLPHADVAWVSSLRPGLHKDMSSEEQSLYYRQWTSARQHHADYSNQPDPISGARTLHPRRLLLTGPPQVGKTGSYLQFLRILFRMLIRLLEVDVYNEEEINTDHSDDSELSQSEGEPWPDIETFSKMPFDVSVHDPKYRLMSLVYSEKLAGIKQEVIKEYKVEEPRQRETMSMMLTQYAAYNTFHHCEQCQQYMAFTPASQMSDSTLHAFTFSSSMLGEEVQLYFIIPKSKESHFVFSKQGRHLESMRLPLVSDKNLNAVKSPIFTPSSGRHEHGLLNLFHAMEGISHLHLLVVKEYEMPLYRKYWPNHIMLVLPGMFNNAGVGAARFLIKELSYHNLELERNRLEELGVKRQCVWPFIVVMDDSCVLWNIHSVQEQTSQPTEAGISSKNVSLKSVLQHIEATPKIIHYAILGIQKWNSKLTSQSLKAPFSRCHVHDFILLNIDLTQNVQYDFNRYFCEDVDFNLRTNSSGLLICRFNNFSLMKKHVQVGGQRDFIIKPKLMVSENVVPILPLQYVCAPDSEHTLLAAPAQFLLEKFLQHASYKLFPKAIHNFKSPVLAIDCYLNIGQEVAICYVSSRPHSSNVNCEGVFFSGLLLYLCDSFVGADLLKKFKFLKGATLCVICQDRSSLRQTIVRLELEDEWQFRLRDEFQTANSSDDKPLYFLTGRHV
Protein: Histamine H1 receptor (H1R) (HH1R) (P31389)
Organism: Cavia porcellus (Guinea pig)
Function: In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
Subcellular location: Cell membrane {ECO:0000269|PubMed:8282735}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P35367}.
Interaction partners:
- Guanine nucleotide-binding protein subunit alpha
- Histamine H2 receptor
- Guanine nucleotide-binding protein subunit alpha
- Guanine nucleotide-binding protein subunit alpha
- Guanine nucleotide-binding protein subunit gamma
- G protein subunit beta 2
- G protein subunit alpha 15
- Histamine H4 receptor
- G protein subunit beta 4
- Beta-transducin
Sequence:
MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAPTSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSLPSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSEDEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFPITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGCIMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTFKRILRIPP
Protein: Phosphate-binding protein PstS 3 (PBP 3) (PstS-3) (Antigen Ag88) (P9WGT7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Functions in inorganic phosphate uptake, is probably the main carrier for phosphate uptake, it is the most highly expressed of the 3 PstS proteins under phosphate starvation. Binds phosphate; probably able to bind both H(2)PO(4)(-) and HPO(4)(2-). Part of the ABC transporter complex PstSACB involved in phosphate import (Probable). Probably plays a role in host phagosome maturation arrest.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Phosphate transport system permease protein PstA 1
- Phosphate transport system permease protein PstC 2
- Phosphate transport system permease protein PstC 1
- Phosphate import ATP-binding protein PstB 1
- Phosphate transport system permease protein PstA 2
- Phosphate import ATP-binding protein PstB 2
- Phosphate-binding protein PstS 1
- Phosphate-binding protein PstS 2
- Uncharacterized oxidoreductase Rv0927c
Sequence:
MKLNRFGAAVGVLAAGALVLSACGNDDNVTGGGATTGQASAKVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGAGISEFNGNQTDFGGSDVPLSKDEAAAAQRRCGSPAWNLPVVFGPIAVTYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVVFRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAAKNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATISGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFLQSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA
Protein: High mobility group 20B (B5MDG7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSHGPKQPGAAAAPAGGKAPGQHGGFVVTVKQERGEGPRAGEKGSHEEEPGSAAGEETRLAQGQEAEEDSAEWAQGTGHGLRALPERAARADPHAPPGSALSRDHQDAGRRVEQAAANGKAGFPCFKPSGAAPQRYLDEAEREKQQYMKELRAYQQSEAYKMCTEKIQEKKIKKEDSSSGLMNTLLNGHKGGDCDGFSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVP
Protein: Coatomer subunit beta' (Q6JWU7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004347, ECO:0000256|PIRNR:PIRNR005567}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004347, ECO:0000256|PIRNR:PIRNR005567}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004347, ECO:0000256|PIRNR:PIRNR005567}. Golgi apparatus membrane {ECO:0000256|PIRNR:PIRNR005567}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR005567}; Cytoplasmic side {ECO:0000256|PIRNR:PIRNR005567}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000256|PIRNR:PIRNR005567}.
Interaction partners:
Sequence:
MPLRLDIKRKLTARSDRVKSVDLHPSEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPYILTSSDDMLIKLWDWEKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHDKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCVNFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVSGLRGSNSVALGYDEGSIIIKLGREEPAMSMDTNGKIIWAKHSEIQQANLKAMGDAEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALRNKSFGSAQEFVWAHDSSEYAIRESSSVVKIFKNFKEKKSFKPDFGAEGIYGGFLLGVRSVNGLAFYDWENTELIRRIEIQPKHIFWSDSGELVCIATEESFFILRYLSEKVAASQENNEGVTEDGIEDAFEVLGEIQEVVKTGLWVGDCFIYTSSVNRLNYFVGGEIVTIAHLDRTMYLLGYIPKDDRLYLGDKELNIVSYSLLVSVLEYQTAVMRRDFGMADKVLPTIPKEQRTRVAHFLEKQGFKQQALAVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFGLAQECLHHAQDYGGLLLLATASGNASMVAKLAEGAERDGKNNVAFMTYFLQGKLDNCLELLIKTNRLPEAAFLARTYLPSQVSRVVKLWRESLSKVNQKAAESLADPTEYENLFPGLREAFVAEQYLKETSLGQTRPASDYPLITPNEERNVLEEASGYEPKGILPAPTQLKQEVSEDEEVLASVSSVSAVSSAQSQPDPKLQEKTEEKTPEITAAEQKVIDELEDDLDNMEFDDIDTTDVNLDDGYVDD
Protein: Transcription factor GTE8 (Bromodomain-containing protein GTE8) (Protein GLOBAL TRANSCRIPTION FACTOR GROUP E8) (Q9LK27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- RuvB-like helicase
- RuvB-like helicase
- SWR1-complex protein 4
- RuvB-like protein 1
- SWR1 complex subunit 2
- SPT2 chromatin protein
- Aldolase like
- SPT2 chromatin protein
- Ubiquitin-conjugating enzyme E2 variant 1B
- Sister chromatid cohesion 1 protein 2
Sequence:
MVESAAFPGGYYRNTFEAPEESEGSGSSAQIDTEVTASENSSTPARKCIMLNSNDEDPYGVQRQVISLYNMSQSERKDLIYRLKLELEQTKIVLKNAELQRMNPAAVSSTSDRVGFSTGQKISSRVSNSKKPSDFAVGSGKKVRHQNGTSRGWNRGTSGKFESSKETMTSTPNITLMKQCDTLLRKLWSHPHSWVFQAPVDVVKLNIPDYLTTIKHPMDLGTVKKNLASGVYSSPHEFAADVRLTFTNAMTYNPPGHDVHIMGDILSKLFEARWKTIKKKLPPCSMQTLPAVTLEPNDERKAAISVPPAKKRKMASPVRESVPEPVKPLMTEVERHRLGRQLESLLDELPAHIIDFLKKHNSNGGEIAEDEIEIDIDVLSDEVLVTLRNLLDEYIQNKEAKQTNVEPCEIELINGSRPSNSSLQRGNEMADEYVDGNEPPISRSSSDSDSGSSEDQSDDAKPMVQGDSSKMPETANSEAQRDENTRIDDLFVGSQSTGALEQMDICSQQKLSSDESDGQHEGNILETPASSEKRYRAALLKNRFADIILKAREKPLPQNGIKGDPERLRKEREELVLQKKKEKARLQAEAEAAEDARRQAEAEAAAEAAAEAKRKRELEREAARQALLKMEKTVEINENSRFLEDLEMLSSSAPEQLPSSAEETSPERPLDALGSFNLRGSNPLEQLGLYMKQDDDEEEPEAPAVPKPDETSTERPLDALGSFKLGECNPLEQLGLYMKQDDGEEEEPEAPVVPKPNETSLERPVDAFGSFNLKGSNPLEQLGLYMKQDDDEEEPEAPAVPNLANDVEEGEID
Protein: Interleukin-12 subunit alpha (IL-12A) (E7ENE1)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU363133}.
Interaction partners:
Sequence:
MCPARSLLLVATLVLLDHLSLARNLPVATPDPGMFPCLHHSQNLLRAVSNMLQKNESCLNSRETSFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS
Protein: [histone H3]-trimethyl-L-lysine(4) demethylase (EC 1.14.11.67) (A6N6J7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLLQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGRLQCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRPEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSLLPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEQ
Protein: endothelin-converting enzyme 1 (EC 3.4.24.71) (A0A8I6B1B3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000256|ARBA:ARBA00004250}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004194}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004194}. Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MNVALQELGSGGSMVEYKRAKLQDEELPEVTVEGRAIQDSLEVGSQKRTRQLFGSHTQLELVLAGLILVLAALLLGCLVALWVQYHRDPVHSTCITEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPSGRSRWNTFNSLWDQNQAILKHLLENSTFNSSSEAERKTRSFYLSCLHLERIEKLGAKPLQDLIDKIGGWNITGPWDEDNFMEVLKAVAGTYRAAPFFTVYVGADSKSSNSNIIQVLAAYLDYMVELGMLLGGQPTSTRAQMQQVLELEIQLATITVPQDQRRDEEKIYHKMSISELQTLAPSMDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEETLENLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPRELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDQEGNLRPWWQNESLTAFQNHTACMEEQYNQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Protein: Small ribosomal subunit protein uS8 (40S ribosomal protein S15a) (Ribosomal protein S24) (P46793)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein eS8
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS11
- Large ribosomal subunit protein bL27m
- Small ribosomal subunit protein uS3
- Elongation factor Tu
- Eukaryotic translation initiation factor 1A
- Small ribosomal subunit protein eS7
Sequence:
MVRISVLNDCLNSIVNAERQGKRQVLVRPSSKVIVKFLEVMMKKRYIGEFEIVDDHRSGKIVIDLIGRINKCGVISPRFDVTLDEIEKWASYLLPSRQFGHIVLTTSLGIMDHNEAKTRHTGGKLLGFFY
Protein: Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (2-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.62) (Acyl-CoA:monoacylglycerol acyltransferase LPGAT1) (EC 2.3.1.22) (Lysophospholipid acyltransferase 7) (LPLAT7) (EC 2.3.1.-) (Stearoyl-CoA:1-lyso-2-acyl-PE acyltransferase) (Q91YX5)
Organism: Mus musculus (Mouse)
Function: Lysophospholipid acyltransferase involved in fatty acyl chain remodeling of glycerophospholipids in the endoplasmic reticulum membrane. Selectively catalyzes the transfer and esterification of saturated long-chain fatty acids from acyl-CoA to the sn-1 position of 1-lyso-2-acyl phosphatidylethanolamines (1-lyso-PE, LPE), with a preference for stearoyl CoA over palmitoyl CoA as acyl donor. Acts in concert with an unknown phospholipase A1 to convert palmitate PE species into stearate ones. Provides substrates to the PE methylation pathway, controlling stearate/palmitate composition of PE and phosphatidylcholine (PC) species with an overall impact on de novo hepatic lipid synthesis, body fat content and life span. Can acylate lysophosphatidylglycerols (LPG) using various saturated fatty acyl-CoAs as acyl donors (By similarity). Can also acylate monoacylglycerols with a preference for 2-monoacylglycerols over 1-monoacylglycerols. Has no activity toward lysophosphatidic acids (LPA) and lysophosphatidylcholines (LPC).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q92604}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q92604}.
Interaction partners:
- Lysophosphatidylcholine acyltransferase 1
- Cardiolipin synthase
- Lysophosphatidylcholine acyltransferase 2
- Lysophosphatidylcholine acyltransferase 2B
- Lysophospholipid acyltransferase LPCAT4
- Lysocardiolipin acyltransferase 1
- Microsomal triglyceride transfer protein large subunit
Sequence:
MAVTVEEAPWLGWIVAKALMRFAFMVANNLVAIPSYICYVIILQPLRVLDSKRFWYIEGLMYKWLLGMVASWGWYAGYTVMEWGEDIKAIAKDEAVMLVNHQATGDVCTLMMCLQDKGPVVAQMMWLMDHIFKYTNFGIVSLIHGDFFIRQGRAYRDQQLLVLKKHLEHNYRSRDRKWIVLFPEGGFLRKRRETSQAFAKKNNLPFLTHVTLPRFGATNIILKALVARQENGSPAGGDARGLECKSRGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPIGDVPLETEDLTSWLYQRFIEKEDLLSHFYKTGAFPPPQGQKEAVCREMTLSNMWIFLIQSFAFLSGYLWYHIIQYFYHCLF
Protein: GPN-loop GTPase 3 (EC 3.6.5.-) (Factor of eukaryotic transcription 5) (O14443)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- GPN-loop GTPase 1
- Uncharacterized protein C530.07c
- Putative RNA polymerase II subunit B1 CTD phosphatase rtr1
- DNA-directed RNA polymerase II subunit RPB3
- U4/U6.U5 tri-snRNP-associated protein 3-like protein C162.01c
- Uncharacterized protein C20H4.06c
- DNA-directed RNA polymerase II subunit RPB2
Sequence:
MVKVAAFVCGVASSGKSTFCGALMSYMKSVGRSCHLVNLDPAAENFEWEPTVDIRDLISIDDVMEELDYGPNGGLIYCFEFLMENLDWLNEEIGDYDEDYLIFDMPGQIELYTHVPILPALIRHLQVTLNFRPCAVYLLESQFLVDRTKFFAGVLSAMSAMVMMEVPHINLLSKMDLLKDNNNITKAELKRFLNTDPLLLTGEINETTNPKFHELNRCIVQLIDDFNMVNFLPLESGNEESVSRVLSYIDDATQWYEDQEPKDPDRFEADDLEDDE
Protein: Ethylene-responsive transcription factor ERF122 (Q38Q40)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MLTPFCSSHHLQEKMNSCQSNPTKMDNSENVLFNDQNENFTLVAPHPSSSYLTRDQEHEIMVSALRQVISNSGADDASSSNLIITSVPPPDAGPCPLCGVAGCYGCTLQRPHREVKKEKKYKGVRKKPSGKWAAEIWDPRSKSRRWLGTFLTAEMAAQSYNDAAAEYRARRGKTNGEGIKRRWR
Protein: Probable biotin-dependent acyl-coenzyme A carboxylase beta3 subunit (EC 2.1.3.-) (P9WQH9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate.
Interaction partners:
- Probable fatty acid synthase Fas
- Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit
- Biotin-dependent acyl-coenzyme A carboxylase alpha3 subunit
- Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit
- Possible carboxylase
- Mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III
- Enoyl-[acyl-carrier-protein] reductase
- 3-oxoacyl-[acyl-carrier-protein] synthase 1
- 3-oxoacyl-[acyl-carrier-protein] synthase 2
- Malonyl CoA-acyl carrier protein transacylase
Sequence:
MSRITTDQLRHAVLDRGSFVSWDSEPLAVPVADSYARELAAARAATGADESVQTGEGRVFGRRVAVVACEFDFLGGSIGVAAAERITAAVERATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAIQLHNQARLPYLVYLRHPTTGGVFASWGSLGHLTVAEPGALIGFLGPRVYELLYGDPFPSGVQTAENLRRHGIIDGVVALDRLRPMLDRALTVLIDAPEPLPAPQTPAPVPDVPTWDSVVASRRPDRPGVRQLLRHGATDRVLLSGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGSTVGPAALREARRGMALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHCLAELVTLDTPTVSILLGQGSGGPALAMLPADRVLAALHGWLAPLPPEGASAIVFRDTAHAAELAAAQGIRSADLLKSGIVDTIVPEYPDAADEPIEFALRLSNAIAAEVHALRKIPAPERLATRLQRYRRIGLPRD
Protein: Synapse differentiation-inducing gene protein 1-like (Capucin) (Caudate and putamen-enriched protein) (Dispanin subfamily C member 1) (DSPC1) (Synapse differentiation-induced protein 2) (Transmembrane protein 90A) (Q3USQ7)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:16359841}.
Interaction partners:
- Vertnin
Sequence:
MESLSELQNPLLPRSPTHLHRPYPYPEAPPGWSCQEQLYSFLLGGAGPARAHQLLDPGSLQLAVEAWYRPSCLLGRDKVKEPKAGSCETSFTEAREPLAGPAEEGSEPGQAAEDVTIHTVSYGVQEELQGQEDSQEEESDGTSSESECEDAFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLSIAVGAGLYVAVVVALAAYMSQNGHG
Protein: Remorin family protein (Remorin-like protein) (Q9SMT2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alcohol dehydrogenase-like protein
- Alcohol dehydrogenase-like protein
- D111/G-patch domain-containing protein
- Remorin family protein
- TORTIFOLIA1-like protein 3
- Syntaxin-31
- Syntaxin-32
- S-protein homolog
- At3g24315
- Centromere/kinetochore protein zw10 homolog
Sequence:
MTLEEQKKVIMPEAVASEPSPPSKEEKSDDSKAIVLVVAAKEPTEDKKVGSVHRDAVLVRLEQDKRISLIKAWEEAEKSKVENKAQKKISSVGAWENSKKASVEAELKKIEEQLNKKKAHYTEQMKNKIAQIHKEAEEKRAMTEAKRGEDVLKAEEMAAKYRATGTAPTKLFGFF
Protein: Secreted aspartic protease 2 (ACP 2) (Aspartate protease 2) (EC 3.4.23.24) (Candidapepsin-2) (Pepsinogen-11) (P0DJ06)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors. These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense. Induces host inflammatory cytokine production in a proteolytic activity-independent way. Plays a role in tissue damage during superficial infection. Moreover, acts toward human hemoglobin though limited proteolysis to generate a variety of antimicrobial hemocidins, enabling to compete with the other microorganisms of the same physiological niche using the microbicidal peptides generated from the host protein.
Subcellular location: Secreted {ECO:0000269|PubMed:1447155, ECO:0000269|PubMed:8478090, ECO:0000269|PubMed:9841840}.
Interaction partners:
Sequence:
MFLKNIFIALAIALLVDATPTTTKRSAGFVALDFSVVKTPKAFPVTNGQEGKTSKRQAVPVTLHNEQVTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQKGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSIDQGILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNSPDAATGQIIFGGVDNAKYSGSLIALPVTSDRELRISLGSVEVSGKTINTDNVDVLVDSGTTITYLQQDLADQIIKAFNGKLTQDSNGNSFYEVDCNLSGDVVFNFSKNAKISVPASEFAASLQGDDGQPYDKCQLLFDVNDANILGDNFLRSAYIVYDLDDNEISLAQVKYTSASSISALT
Protein: AT13666p (Q8MZC7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
AQLQVPAQAQAQFHDCPKALVPQHANLRGQLCVSEAPADPLGSAVHHPRVQHRPRAARAAPELAAHPLRAGDSRQPDAESAPEAAAQWCGGHSSWRHHHAGSAAATDLASRDEQAFEAALQDEWARYGWCCFQCIHGGGRGGLDRYALCEAPLLRLFAHHVPAAAAGWQAGKESATEAPQEAAEEPEKVATAAAAAGGSTGAALAQLHLEWQGVQRGIQASGRWCCWSCRCCRCFRWWKQPICTWQTWKAPVEARAAHVK
Protein: Leucine-rich repeat protein (LRRP) (Q38BT2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MYTVAPAPGCLSRQLHVSGRNKNIKDIDLGAVFFTHEDKETLALITSFDLSHNCIEKLLHLDALVSLTSLDVSHNRINVVGTLPITITRLNLSNNGLVTLDNVGALRNLRELDVSHNRLDSFIGLRSISTLQILRADNNRIFSVSELGCMTSLHFLSLDHNVIRNVNELVFLTSTKHLEMLSLCGNPVSNMKGYKKLITQLCPGLLSLDGLPLASDTSECVVDVPDDDEEDEELLTPVARLGPCPAPHPLLKTNRAVHGGNVRVNGFLLVEGQGGESATGKGGRADSSVRRSVVATKCCGNKQSAATETGKPPENDLSSIKVASSDTSVSSKQRDSLNVGPEGSERPQRGMQKQRKLQQLQTRGSGVEAPTISKTTSSYASKIASKVSHHSSEEKDGSSSFSGSQPSRDTERLLRETQVLVEELRKENGYLRARNKKIEAQLREVRRVVTHQLDDITDLRKRCAAAESLVAASKEQMEKVKRHARATGKYTHSAVDAMALEQERLRAGYEAQIADLNVQLRDAQMRSKKATMCPIQQSRSGKVLTLNTEDINGACTEIEISLGEGMSSPTREGCELSLVLSPTDTTTSDSERSVTRDFCDDAGVLNGSVNTSGIHKPKGTRDTEESACLE
Protein: Alpha-protein kinase 3 (EC 2.7.11.1) (Myocytic induction/differentiation originator) (Midori) (Q924C5)
Organism: Mus musculus (Mouse)
Function: Involved in cardiomyocyte differentiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:11418590}.
Interaction partners:
Sequence:
MGSRRAAGRGWGLGGRAGAGGDSEDDGPVWTPGPASRSYLLSVRPEASLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSDVRFTCIVTGYPEPEVTWYKDDIELDRYCGLPKYEITHQGNRHTLQLYRCQEEDAAIYQASARNTKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKMREIEQSWKHGKEASGEADTLLRKISPDRFQRKRRLSGVEEAVLSTPVREMEEGSSAAWQEGETESAQHPGLGLINSFAPGEAPTNGEPAPENGEDEERGLLTYICEVMELGPQNSPPKESGAKKKRKDEESKPGEQKLELEKAEGSQCSSENVVPSTDKPNSSRREKSTDTQPAQTQPRGRVARGPGIESTRKTASVLGIQDKVQDVPAPAPAPVPAPALAPAPVPVPAPTPVPSRSSEQVYFSLKDMFMETTRAGRSQEEEKPPPPSTRVAGESPPGKTPVKSRLEKVPMVSSQPTSSMVPPPIKPLNRKRFAPPKSKVESTTTSLSSQTSESMAQSLGKALPSASTQVPTPPARRRHGTRDSPLQGQTSHKTPGEALESPATVAPTKSANSSSDTVSVDHDSSGNQGATEPMDTETQEDGRTLVDGRTGSRKKTHTDGKLQVDGRTQGDGAQDRAHASPRTQAGEKAPTDVVTQGSERPQSDRSSWKNLVTQRRVDMQVGQMQAGERWQQDPGDARIQEEEKETQSAAGSIPVAFETQSEQLSMASLSSLPGALKGSPSGCPRESQAIECFEKSTEAPCVQERSDLMLRSEEAAFRSHEDGLLGPPSGNRTYPTQLPPEGHSEHLGGQTHQRSEQEDSLSQCPKKEQPQEPLHVGLSGGHSTGLSQEVPAMPSLPGTGLTSSLQEELPGTAASLHTNTDVPLPSRDQDFPSSAPTLQLGPGSPTQSHPPEAMATSSEGACAKEPNVDGRSSGTRSCDPGLIDSLKNYLLLLLKLSSPETSEARAESQEVADTGGLTSSSTLVPTMEVAGLSPRTSRRILERVENNHLVQSAQTLLLSPCTSRRLTGLLDREVQAGQQALAAAQCSRGPCPTPLTIPAIVVGEEGSAGEDSEERTSQESDKKGLLGEVEGHTVESRTQEPCQEEAMPGEALTGLPAATPEELALGARRKRFLPKVRAGSDGEANKAEERESPTVSPRGPRKGLTPGSPGTPGRERRSPTQARKASMLEVPGAEEEPATGDLVSRSKDSGLDSEPAVDEGKQEALAKQRKAKDLLKAPQVIRKIRVEQFPDSSGSLKLWCQFFNIVSDSVLTWAKDQHPVGEVNRSAGDEGPAALAIVQASPTDCGVYRCTIQNEHGSASTDFCLSPEVLSGFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGHGLQKASRAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLLGRNYDVTIQGCKIQNMSREYCKIFAAEARAASGFGEVPEIIPLYLIYRPANNIPYATLEEDLGKPLQTYCSRQWGCAGAPAAASSSEALQKCQTFQHWLYQWTNGSFLVTDLTGADWKMTDVQIATKLRGYQGLKESCFPALLDQFASSHQCNTYCDMLGLKPLKGPEAAHPQAKAKGSKSPSAGRKGSQLSPQPQKKGLPSPQGSRKSAPSSRATLQASQAATVQLLGQPPVQDGSSKAQSMR
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q388Q0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MENFVLPPYTVSQKLGSGTFSTVRLATDEQRRRWAVKIIDKAKLRKEEMEGQLMREVEAMRVFKHENIIAFHDFKETPTHYCLVLEFVSGGELFDKIVAAKRFDEPTARRYFQQLIAGVHHCHGKGFAHRDLKPENLLLDAVGVLKISDFGFCSNGSGDSDLPSSRAMGTPNYIAPEALSGSDHNAFAADIWSCGVILYVMLAGKLPFEDRNQKSLLEKVKRGEYAMLRQVSEAVRDLVKRMLTVDPQNRITLEGIISHPWFAVGWDPKCLKEAA
Protein: Chaperone protein DNAJ, putative (Q38DS8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFVDYYAVLNLHPSCTAKEIREAFKRFALLCHPDRTDADQSRNFSEVKDAYDVLSDPARRYLYDLGYADAISAIQRQTLMQKKGRDVEAVAPVVRSPQPFFSSTTSSLNSASSPSAYSQPTMPPCSHPCDKRDSPMGSLGPSLAQDYQQGSAFRAVRGHHHAVRRNQVSWTHGSEERSYDSRAASLFANMPADKEEECQSKPSPPRPRVGKRIPPKAPSGCVKRSRAGSSRCPLPHCTVGPNIVLGTKVTAVSLEGEGHCLQRHLKMPTNEAINASIIKTWGVFFNI