wanglab/gogpt-training-data huggingface dataset:
Protein: Barrierpepsin (EC 3.4.23.35) (BAR proteinase) (Extracellular 'barrier' protein) (P12630)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: This protein called 'barrier activity' is excreted by yeast cells mating type a. It is probably a protease that cleaves alpha-factor and thus acts as an antagonist of this mating pheromone and establishes optimal pheromone concentration for conjugation.
Subcellular location: Secreted.
Interaction partners:
- Pheromone alpha factor receptor
- Mating factor alpha-1
- Mating factor alpha-2
- Alpha-factor-transporting ATPase
- Protein SST2
- A-agglutinin-binding subunit
- Mating hormone A-factor 2
- Mating hormone A-factor 1
- Orotidine 5'-phosphate decarboxylase
- Protein ASG7
Sequence:
MSAINHLCLKLILASFAIINTITALTNDGTGHLEFLLQHEEEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKPSIDCRSMSTYNEHRSSTYQYLENGRFYITYADGTFADGSWGTETVSINGIDIPNIQFGVAKYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLFLNSPDSGTGSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSSCEHETFTTTKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPVSVGDVEYNFDFGDLQISVPLSSLILSPETEGSYCGFAVQPTNDSMVLGDVFLSSAYVVFDLDNYKISLAQANWNASEVSKKLVNIQTDGSISGAKIATAEPWSTNEPFTVTSDIYSSTGCKSRPFLQSSTASSLIAETNVQSRNCSTKMPGTRSTTVLSKPTQNSAMHQSTGAVTQTSNETKLELSSTMANSGSVSLPTSNSIDKEFEHSKSQTTSDPSVAEHSTFNQTFVHETKYRPTHKTVITETVTKYSTVLINVCKPTY
Protein: Parathyroid hormone-like hormone a precursor (Parathyroid hormone-related peptide 1) (Q1L5E8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MRMLCCRRVLQQWVFALFLLCSPVPHHGRPVDALSSRMKRSVTHAQLMHDKGRTLQDFKRRMWLQELLHEVHTAEIREAQQPRGGVSISSGAGGGVGAGVSITLPAGVGVSTGAGTAHPKPAGGTKNLPIGFGLEDEEGTNLPQETHKSQNYKDNMMKGIRRKKKSRTGKRREGEKRKRRARSLQEFSSGVHLQPYSC
Protein: Iron-sulfur cluster assembly enzyme IscU (fIscU) (Q9VHK6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- LYR motif-containing protein 4 homolog
- Cysteine desulfurase, mitochondrial
- Molybdenum cofactor sulfurase
- Frataxin homolog, mitochondrial
- Iron-sulfur cluster assembly 1 homolog, mitochondrial
- Iron-sulfur cluster assembly 2 homolog, mitochondrial
- GEO02460p1
- Adrenodoxin-like protein 2, mitochondrial
- GH14121p
- Adrenodoxin-like protein 1, mitochondrial
Sequence:
MSLVRNSSRLLRSQLKRVQSVPVALYHENVVEHYENPRNVGSLDKKDVTVGTGLVGAPACGDVMKLQIKVDENGKIVDAKFKTFGCGSAIASSSLATEWVKGKSIDEAGKLKNTDIAKELRLPPVKLHCSMLAEDAIKAALADYKVKQQKKVAN
Protein: Hairy/enhancer-of-split related with YRPW motif protein 2 (Cardiovascular helix-loop-helix factor 1) (hCHF1) (Class B basic helix-loop-helix protein 32) (bHLHb32) (HES-related repressor protein 2) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HRT-2) (hHRT2) (Protein gridlock homolog) (Q9UBP5)
Organism: Homo sapiens (Human)
Function: Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Hairy/enhancer-of-split related with YRPW motif protein 1
- Neurogenic locus notch homolog protein 1
- Hairy/enhancer-of-split related with YRPW motif-like protein
- Protein jagged-1
- Recombining binding protein suppressor of hairless
- Neurogenic locus notch homolog protein 4
- Neurogenic locus notch homolog protein 3
- Transcription factor HES-1
- Neurogenic locus notch homolog protein 2
- Transcription factor GATA-4
Sequence:
MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
Protein: Na+/H+ antiporter subunit G (Q9I4R5)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable NADH dehydrogenase
- K+/H+ antiporter subunit F
- Na+/H+ antiporter subunit C
- Na+/H+ antiporter subunit E
- Probable NADH dehydrogenase
- NADH-quinone oxidoreductase subunit L
- NADH-quinone oxidoreductase subunit C/D
Sequence:
MTGEPLSLWLEIIVSAFLLLGSAFVLIGAIGLYRLPDFFMRLHGPTKATTLGVGGVIVASLIYFSNRQAGISLHELLISLFLFISAPVSAYMLAKAAVLQQLPLEKKTRGKPWEQ
Protein: Uncharacterized protein (Q38A67)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTARFTALCEELSRLQVRALRRDGNPLDIAVEAIRAIRINRDSIEPLRQNIPHVPLFLRSCATLLSRSVTSEADDAIESTGRLAEVYVGGNHGDVNDSAAVLQSLVQLSRVRCERAACVGDAAKVLSSSLKPLVPAALHNTLQKWQQHKVRPHTSSLLSLLRGTDAVYGGSFQFTPVGADMMGLLPIKSKVQMEAKMQKCEHSRDILRALCEMQFSKLDAGICLTSQAECGFYQSELCNICCEVLFSTHALMTSQQLAQVVHSLGVLQHRHIHQKFFSSLIDFKNCNAEAVRQHIMGLAMLRQPPPNDRRLMDGVFLHVFRPTDPLDYDSSPEAALSPGWFVDVGHALTCLGITHHKYRLTMARTVRRSIASMSTQERCKLLYGLGGVSLDSVPAELQGSWKGKVIRTIEVLEQRLRSNVDPVDGPSVMHALLFAGIREHPMIPQQPDLASNENPVETLLRTWATCPRERVLYLTEQIRPSHLGSDPATTLSHVCGIIANNCGGVGTDSYRFGPLCDVIRTHGGSMTVDEAMSTIEAIERMKAGDRFSGALVSLLGSLWNQRESMTPEQRMRCCRLLENVGHLEIAVNLLDYIVSQ
Protein: Mitochondrial import inner membrane translocase subunit TIM8 (Q9XGY4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex mediates the import of some proteins while the predominant TIM9-TIM10 70 kDa complex mediates the import of much more proteins (By similarity).
Subcellular location: Mitochondrion intermembrane space {ECO:0000269|PubMed:14730085}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM13
- Mitochondrial import inner membrane translocase subunit TIM10
- Mitochondrial import inner membrane translocase subunit TIM9
- Mitochondrial intermembrane space import and assembly protein 40 homolog
- Mitochondrial import receptor subunit TOM40-1
- Mitochondrial import inner membrane translocase subunit TIM50
- Probable mitochondrial import inner membrane translocase subunit TIM21
- Mitochondrial import inner membrane translocase subunit TIM22-1
- FAD-linked sulfhydryl oxidase ERV1
- Mitochondrial import inner membrane translocase subunit TIM22-4
Sequence:
MDPSMANNPELLQFLAQEKERAMVNEMVSKMTSVCWDKCITSAPGSKFSSSESSCLTHCAQRYMDMSMIIMKRFNSQ
Protein: MIZ-type zinc finger-containing protein (PIAS homologue) (Q555X5)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Signal transducer and activator of transcription A
- SP-RING-type domain-containing protein
- Signal transducer and activator of transcription
- Small ubiquitin-like protein
- Ubiquitin-like protein
- Sumo-conjugating enzyme ubc9
Sequence:
MVSHRFSTVEQKEIVEGVFSRDQNTFNNYFVSKIFDLKKLKVDEIKAILKIVRHYRPNTRLQGNKPQLLSSLESIAFGPSSSSSSSSSSSSSSSSSHHNHNHNNNRIAPPTPQYALKPNAIYLQQRLQEIERIHNAQRQLESIYPNISTNNNNSTTTTTTTNNNSNYNSSNNNSNSNNNFNYNNNNNNYNNNNYNNYNNYNNNYNNNNYNYNGSINSEHHNQASNNFQLQVQKLNGGINNFTDNVQEPPRQYKDTMQNITRFIFTMQNKSSSDYNNPSVQKKLQLNDSSFEEKQSPFFQELDKLVITSFVSTVTVSFSLDLETWKIIEAAQQKLLNPSLPPPPLKDDYSIQIRLYNKQSGSDIHYGSDIYLSVNGKSINNEQFKKIRTKSFSNPCVIQKPIDITHLVKRSDNRVNLQIQNRTSGIMVVQLLKNQTLQQVVEEIKMKSEMEESQSADKRQKKNEDDLEELTYDLTVRCPLSFKRIEYPAKSKKCTHNQCFDLCSFTEYSNQQQLWNCPICHAVAPPNLLLIDPFFQKLLSQAPSTCEIITIFPDGHWEYKNESAENFSDDDGKDDADGGGDGDKTTTTANNIEIVDLLDSDDDGNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNDIPTQTVSTSSVATTMTPSTLTTLDQSATTLDQSATTLDQLAAASTTTTTTTNLGSESVPYDEEEEEEEDSGDSDEFRSSPIEEEEGEEEDEEEEEEEDSGDSEIYSFYSRAGINAGEDEEDDDEDEDDDDECECGKVHSNKRKNILHSSVYYRNEFLKNAKKNKKNSDNNNTNINNINNINNNNNSRNNSATDPIVIDDD
Protein: Protein 4.1 (Band 4.1) (Erythrocyte membrane protein band 4.1) (A0A2R8Y6G5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGVSTLST
Protein: 4-nitrobenzoate reductase (4NBen reductase) (EC 1.7.1.-) (Q9FD36)
Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
Interaction partners:
Sequence:
MALLTDDFDAVVASRRAVRAFLPTPISRKLISEIIDIARLAPSNSNTQPWSIHVLTGEPKQALSALLGIAHNDPSADPLAHLPDDLARKYRERQEKWGELFYGLHQIDKCDDAGRARVSGLNFDFFGAPVGLIFTIDSNLKKYSWLDYGLFLQTLMLTARSRGLSTCPQVSFARFQSLIKDFLHLDDSQEIVCGMSLGYADENATVNSLRMPREMAQGFTHFMGFDR
Protein: ATP-dependent DNA helicase tlh1 (EC 5.6.2.4) (DNA 3'-5' helicase tlh1) (Sub-telomeric helicase RecQ homolog 1) (Telomere-linked helicase 1) (P0CT33)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Exhibits ATP-dependent 3' to 5' DNA helicase activity and has a role in telomerase-independent telomere maintenance.
Interaction partners:
- DNA repair protein rhp51
- DNA topoisomerase 3
- Putative MutL protein homolog 1
- ATP-dependent DNA helicase srs2
- Replication factor A protein 1
- UPF0494 membrane protein C212.04c
- RecQ-mediated genome instability protein 1
- Exodeoxyribonuclease 1
- ATP-dependent DNA helicase II subunit 1
- Uncharacterized GPI-anchored protein C212.08c
Sequence:
MVVASEIAKVASKTARDIAGCFTCQCGTQFDNVERIVQHFKECRYRDETCKDDDIVVYEPSSFVQDEKKDKPIIVEAASEATSEEACNSSKERQLPALSALSALSTLTTSANDDLWTARLIWQSTNDTKLDNSPSSNYTDLNHKLANYGLSILSIHALMCVECECLLNVIHTAQHMQIVHKLELNEDLLWFQELRTLKLKSPTNVLQTHSSQTHVYPYIRGLPVLLNGYECVPCTKNGTGFVHAIMDTFRHHVRRTHGKVIKLENCIRRTALQTVKNKYAQRCQFFKVDYVPLNGGEEEEEEEGEEKEDAQNIKERMVDFCFSKFMEKNQQRREQQDKGENKKRQDDVDQATDNNTNTILEDDEKDNDEEEEEEIVNAREKNLLNQQFNWTAIVKKLGENWDQLVRFEYTNGIVTLDTIVNQLIRYYYRGFRHLSGMTMGMRRMFTQGGSYSAQERGLCRLEQKDTVVRYAQSAALYLIFLLRRPSADSGIRRHLEAMCGATVERKEGGSNSSSNISNVANFDSAEDDNDNDNDNDRDSNNNNNNNNTNTDDDDKLAYLELHEALKLAFLQQYDFSKNVQDLEIMEFLACMSLHKDGTSKYAYEISACFAPLIYTCRLVAACELQRLIDEKQIDLLSIPSFQTAGSIAYAHVFCFITLGQRNLYDVLYETQKVVRDIIRTEGYANTLQGLSPSTVLFQPRSNSMYPCIGDAFNNMVRLDLSELTALYEGMFAKVQDLLKELCFDMNVEKLLPISLLRSIGDDINNSKLGYSFFKESIEIRSSHSVLLRTILKNSELCHRFFPSMSKKDLTKLFGGVSDQQRNECDNYSNHYNDNSNDNDNDVFLKLHWSKSAIKKYETKASIFNELLFCLVYISAGQPARAQEMVYWTLRNGKYKTRELYLMFGRLMIYSRYDKTRNMKFAEKPIPRFLSEPLSILALRYYVLVRPLEALMKYVTTADRSKVAVYLDFMFVIAGERLQRDLPYRIFPKATYQCIQKPLGFRNYRHIAHYFKEKNIEEEMTRESYFDLQAGHTRNTALYIYGRTMDNLHYLPSDYFANFFRASYKWQELLQIRDNPTHGLLVETKHPFIKRVDQLEEALNEKLARLVGEQMVEGDKEKDKTNEEKNKDEVKAEMTQPVVNQDSHDLQDQLATTPTAPTAFHYRPGLLQPSQTSVQHCCWALSQYYGLEAKFRSLKQFQSVYFSLLNRMNLITVLPTGGGKSLSFLIPALIEKKRQTPGKVMNMVTLVLVPMMSLRQDMMLRVNEKGLLVCSGNWTAFKDVRLTLETQLPDLFILTYESALTNSGLRFFESLATLGRLARVVIDEAHLLLTSGAWRTALSRASRLSGLYAPLHLLSATFPRQLEMVARQTFCTNFYVLRETSTARENIFYFLHPYDNTEFLLDLRTLMKRTKVFEGDGRAIIFCRTKKDVEYIHRRLHQSDLFAHTHVTIYTGDVSDEERQMNFDAFRNANGKTRIMIATKAFGLGINYMGVRLVVHYGLPASSMDYVQETGRAGRDGKYAIAALFYEKYDSTWSSYVEDSMKNFLNDNTMCVRSFLASEMDGECVCCASFANCVYCSRCSDSLLGEESTVSTMYGVKPTLPETPKPAIATHSRYNASFSSSPPPQPGNSSGMSAMNTNTTSTTPVSLSELSEITLFPSSVSPTWKKSFGNANTNLKYGLEDMSLSHRRGHKRTYDEHLNNVQQGVNHDMNRVHGSVGGMSGIVGIGIGIGDGDGDGDVDSRTIHFAEYKSRVQAVKKQWVDSTDISAQLERFFRVYKDECLSCTLGNPDTEIRAHTGKACPVRLSTCYKCGKADHNLRECKLRIRFQGLCLFCGLTKFEHADSDMAYTSDCRSWARKANLISLVYYAWNNVQYRRTIADKFLQGDVRD
Protein: RNA polymerase II holoenzyme cyclin-like subunit (Suppressor of RNA polymerase B 11) (P47821)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5. The SSN3/SRB10 and SSN8/SRB11 kinase-cyclin pair may also positively and negatively regulate numerous transcriptional activators in response to changes in nutritional and physiological conditions.
Subcellular location: Nucleus {ECO:0000269|PubMed:16630888}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 12
- Mediator of RNA polymerase II transcription subunit 13
- Meiotic mRNA stability protein kinase SSN3
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 5
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 6
Sequence:
MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEARTLWPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI
Protein: Di-glucose binding protein with Leucine-rich repeat domain-containing protein (F4ICJ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Uncharacterized protein At2g04870
- DNA binding protein
- Formin-like protein 12
- Plant UBX domain-containing protein 10
- Growth-regulating factor 6
Sequence:
MPFSPSFFLFLSSFFLLLHLSLSSPFNTSFFIDCGSPETSTDVFNRTWLPDQFYSGGSTAVVSEPLRFHLIAEKTIRYFPLSFGKKNCYVVPLPPGRYYLRTFTVYDNYDGKSHSPSFDVSVEGTLVFSWRSPWPESLLRDGSYSDLFAFIGDGELDLCFYSIATDPPIVGSLEVLQVDPSSYDADGTGQNVLLVNYGRLSCGSDQWGPGFTNHTDNFGRSWQSDEDFRSEDSRSVARSLSTLEKIKGVDQAPNYFPMKLYQTAVTVSGGGSLVYELEVDAKLDYLLWFHFSEIDSTVKKAGQRVFDLVVNDNNVSRVDVFHEVGGFAAYSLNYTVKNLSSTIVTVKLSSVSGAPIISGLENYAIVPADMATVPEQVTAMKALKDSLRVPDRMGWNGDPCAPTSWDAWEGVSCRPNSQGSALVIFQIDLGSQGLKGFISEQISLLTNLNSLNLSSNTLSGQLPLGLGHKSLVSLDLSNNQLTGPIPESLTLSSLKLVLLNGNELQGKVPEEVYSVGVHGGIIDLSGNKGLCGVPSLPTCPLLWENGHLSKGGKIAIAISCVVFLILVFLVIYLCCIWRGRHDYDFAPPHDLTSLAAKRNRYQRQKSLMLLEMESQHAKGMPTLPLNSQ
Protein: Putative agmatinase 1 (EC 3.5.3.11) (Agmatine ureohydrolase 1) (AUH 1) (Q10088)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Spermidine synthase
- Ornithine decarboxylase
- Putative agmatinase 2
- Putative agmatinase 3
- Uncharacterized transporter C11D3.06
- Ornithine aminotransferase car2
- Aromatic amino acid aminotransferase C1773.13
- Arginase
- Uncharacterized transcriptional regulatory protein PB24D3.01
- Putative alanine racemase 2
Sequence:
MALQSLFLILLAGAAQLAQAHPKIFEQSRANAVETFDDAFPGDGETQADSVFSGIATFGRLPYWKCLNDKSQSFDIAFLGAPFDTGTSYRPGARFGPSGIREGSRRLNLYGGYNVPMETNPFNNWAKIVDCGDIPLTSYDNAVAIKQIENGHFELLTRKPTSYSEKDGYALDGSVLPRVITLGGDHTIVLPILRSVSRAYGPVSIIHFDSHLDSWKPKVFGGGKSSVGSINHGTYFYHASQEGLVSNDSNIHAGIRTTLSGLSDYDNDADCGFEIIEAREIDTIGIDAIIKRIRDRVGDGIAYLSIDIDVLDPAYAPATGTPESAGWTTRELRTILRGLDGIKLVGADIVEVAPAYDFAEVTTLAAADILFEVMSIMVKTPVYKEQAKQQSRFY
Protein: Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) (P0A8N3)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm.
Interaction partners:
- Arginine--tRNA ligase
- Leucine--tRNA ligase
- Isoleucine--tRNA ligase
- Methionine--tRNA ligase
- Glutamate--tRNA ligase
- Peptide chain release factor RF2
- Proline--tRNA ligase
- Glutamine--tRNA ligase
- Histidine--tRNA ligase
- Valine--tRNA ligase
Sequence:
MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK
Protein: DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) (Q2U6A1)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q08387}.
Interaction partners:
- ATP-dependent DNA helicase II subunit 2
- ATP-dependent DNA helicase II subunit 1
- Proliferating cell nuclear antigen
- ATP-dependent DNA ligase family profile domain-containing protein
- DNA-directed DNA polymerase
- RAD52 homolog
- DNA repair protein RAD50
- Uncharacterized protein
- Flap endonuclease 1
- Uncharacterized protein
Sequence:
MDSDDDYNGPADTNPRLEDEESDLDEKYPNRPRNHSTTLPFHVLFQTLFYPLSEIKKKPAGPARKKVGPHGLSSVNLTPLEKRRDIIDRFISRWRKEVGDDIYPAFRLILPDKDRDRAMYGMKEKAIGKLLIRIMKIDKNSEDALNLLNWKLPGQTTTSSMAGDFAGRCFGVLSKRPMRTEVGDMTIEEVNEKLDHLSAASKENQQLPILTEFYRRMNPEELMWLIRIILRQMKVGATERTFFDVFHPDAENLYSISSSLRRVCWELHDPNIRLEAEDRGITLMQCFQPQLAQFQMHSLDRMISRMRLTEDDPVFWIEEKLDGERMQLHMDSNDSVPGGRTFRFWSRKAKDYTYLYGNGIQDENGALTRYLSDAFADGVESLILDGEMITWDTEQDAIAPFGTLKTAALSEQRNPYSSTTRPLFRIFDILYLNGRDLTRYTLRDRRNALQKSIKPVYRRFEIHPYEEATGKTEIEEALRRVVEEASEGLVLKNPRSPYRLNERHDDWMKVKPEYMTEFGESLDVVVIGGYYGSGHRGGGLSSFLCGLRVDDAHSSQGMVASKCYSFCKVGGGFTAADYANIRHHTDGKWHEWKSRKPPTTYIELAGGDAQYERPDMWIKPEDSVVLCVKAASVAVSDQFRIGLTLRFPRFKKLRMDKDWKSALSVQEFLDLKANAERERKEKEFNVDNSRKKRAKRDNKKPLAIVGYSAEAEAQYTGPSGNIFEGLNFYITTDSNTPVKKSKAELEQLVKANGGKFFQTSNAAPSTICIADRRTVKAASLQKSGNVNIIRPSWILDCIRQSEIDAGLPDSLLPLEPRHVFFATQDKKEEIAASVDRFNDSYARNTTNDELKEILKQMSKDHHFHASQNPKIVRKLNERIQEKVNAGWEMPSGWLFKGLTILFPQNDKVDDAEVDETSQTHQQYRLNLARNTVRFAGANVVDSKSSSVTHIVVAPGSSSSDVSSIRKSHSAKPGKKVPHLVTAEWIEECWKQRTLLGEEGFQPSRGT
Protein: Tektin-1 (Q32KZ9)
Organism: Bos taurus (Bovine)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:34715025, ECO:0000269|PubMed:37327785}.
Interaction partners:
- Tektin-4
- Piercer of microtubule wall 1 protein
- Protein Flattop
- Outer dynein arm-docking complex subunit 1
- Outer dynein arm-docking complex subunit 4
- Cilia and flagella associated protein 45.
- Tektin-2
- Outer dynein arm-docking complex subunit 2
- Cilia- and flagella-associated protein 52
- EF-hand domain-containing family member C2
Sequence:
MAKLLQQPPKFLRAEWQIANKNQYHRAEAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVRFWKKELDDKLEQLVYATEDLLLYQTRLQKALESFKEPLHITEKCLEYREKRVGIDLVHDEVEQELIKEHEIIRGVMTLLTRTLEETCEQIRLNRSAKYNLEKDLRDKFTAITIDDICFSLNNNSPNIKYSENVVRVEPNSVSLEDWLDFSNTNVEKADKQRNNSLTLKALVDRILFQTASDLRRQCDVVDTAFKNGLKETKDARDKLALHLDKVMEEIASQEKNIVVLEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLIKEVDEITHNVARLKETLAQAHVELKGLNRRQLALQEEIQIKENTIYIDEVLCVPMRKSIPPRDGDDHGEWAGGSHPEAVC
Protein: 5-aminolevulinate synthase, mitochondrial (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-ALA synthase) (Delta-aminolevulinate synthase) (O94069)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:P09950}.
Interaction partners:
- Delta-aminolevulinic acid dehydratase
- Protoporphyrinogen oxidase
- Glycine cleavage system P protein
- low-specificity L-threonine aldolase
- Serine hydroxymethyltransferase
- Serine hydroxymethyltransferase, cytosolic
- low-specificity L-threonine aldolase
- Ifg3p
- Dao1p
- Dao2p
Sequence:
MESITKVSMSVCPFVRSTSTQALRQLSQTSGALANQARQCPIAGNAIRAKEISIRSYSSATKPARATAATPSTPEATFNVTSSFELGSKETAFDYNGYLGNELEKKRSDKSYRYFNNINRLANEFPKAHRTQEEDKVTVWCSNDYLGMGKNENTLKEMKRVLDKYGSGAGGTRNIAGHNSHAIKLESELAALHKHDAALVFSSCFVANDAVLSLLGQKIKDLVIFSDELNHASMIQGIRNSRARKHIFKHNNLADLESKLAQYPKSTPKLIAFESVYSMCGSIAPIEAICDLAEKYGALTFLDEVHAVGMYGPHGAGVAEHLNFEAHLKSGIERPEITTVMSRVDMVTGTLGKAYGVVGGYITGKTNLIDWFRSYAPGFIFTTSLPPAIMAGCSASIRYQRATLKDRIAQQKNTRLVKNNLNELGIPVIPNPSHIVPVLVGNAADAKRASDLLLNKHDIYVQAINFPTVPIGEERLRITPTPGHGPELSKQLVEAVDSVFTELNLNRINDWKKLGGLVGVGVEGAAKVEHIWTEEQLALTDADLNPNVVNPAISPLDVSSGIST
Protein: Calcium-transporting ATPase (EC 7.2.2.10) (E6EK15)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU361146}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361146}.
Interaction partners:
Sequence:
MATIDGRPAQYGISLKQLRELMEHRGREGVMKIAENGGIHELCKKLYTSPNEGLSGSKADEEHRRETFGSNVIPPKPPKTFLTLVWEALQDVTLIILEVAALVSLGLSFYKPADEDAPVLQEEEEHHGWIEGLAILISVIVVVIVTAFNDYSKERQFRGLQNRIEGEHKFSVIRGGEVCQISVGDILVGDIAQVKYGDLLPADGCLIQSNDLKVDESSLTGESDHVKKGPDVDPMVLSGTHVMEGSGKMVVTAVGVNSQAGIIFTLLGAAVDEQEAEIKKMKKGENDGRSQIKGSQAPSQRETVTSEITKSESEGNHLPQSSSSGAAETGHKKEKSVLQAKLTKLAIQIGYAGSTIAVLTVIILIIQFCIKTFVIDEKPWKNTYANNLVKHLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYICEKLCKVLPTLSDIPQHVGNLITMGISVNSAYTSNIMAGHNPGDLPIQVGNKTECALLGFVQGLGVKYQSIRDEITEDKFTRVYTFNSVRKSMGTVIPRPNGGYRLYTKGASEIIMKKCAFIYGHEGTLEKFTRDMQERLIREVIEPMACDGLRTISVAYRDFVPGKAAINEVHIDGEPNWDDEENIMTNLTCLCVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARSIASKCGILRPNDDFLILEGKEFNRRIRDSNGDIQQHLIDKVWPKLRVLARSSPTDKYTLVKGIIDSTVSENREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSIAKFLQFQLTVNVVAVIVAFIGACAVQDSPLKAVQMLWVNLIMDTLASLALATEFPTPDLLLRKPYGRTKPLISRTMMKNILGQALYQLIIIFGLLFVGDVILDIESGRGQELNAGPTQHFTIIFNTFVMMTLFNEINARKIHGQRNVIEGLLTNPIFYTIWIFTMISQVLIIQYGKMAFSTKALTLDQWLWCIFFGIGTLVWGQLITSVPTRKLPKILSWGRGHPEEYTDGMNLGEERFDSIDSDKKPRAGQILWIRGLTRLQTQVIGGELQERLIPVPYSKSNTDQAIRVVNAFRQGLDARYGDHTNTSLAEVLRKQTSLSKRLSETSSIEYADNIPDELTIPEIDVERLSSHSHTETAV