Protein: Voltage-dependent calcium channel type D subunit alpha-1 (DmCa1D) (Q24270)
Organism: Drosophila melanogaster (Fruit fly)
Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Encodes a dihydropyridine- and diltiazem-sensitive current in larval body wall muscle. Vital for embryonic development.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Ca2+-channel-protein-beta-subunit, isoform L
- Uncoordinated 79, isoform C
- Voltage-dependent calcium channel type A subunit alpha-1
- Straightjacket, isoform C
- Stolid, isoform H
- Ca[2+] channel Muscle-specific alpha2/delta subunit, isoform A
- Ca[2+]-channel protein alpha[[1]] subunit T, isoform F
- Stac-like, isoform J
- Calcium-activated potassium channel slowpoke
- VWFA and cache domain-containing protein CG16868
Sequence:
MGGGELVNCIAYDDNTLVIERKPSPSSPSTSRRYLKAETPTRGSRKYNRKSSAKSDLEVVVVKPEHHHQHRSPTITLPVPANPLTTSASAGSSPTGAGLAAGLGTASGTVLQQSCSALDPPEDSNQPSGTRRRPTSTELALSNVTSQIVNNATYKLDFKQRRHKSNNGGSESGSLTGIATGPATSPAGPTGPTSSSGKRRKSSCTSCGGGGISAPPPRLTPEEAWQLQPQNSVTSAGSTNSSFSSGGGRDDNSSYSAVGGDSSSSNSCNCDITGDNSTLHGFGVGDVCSFIADCDDNSEDDDGDPNNQDLSSQTLRTAAIVAAVAAAAKEQAQEQSLADCESFSDRRQDADEDVRIIQDCCGGNNDSLEDVGEVDDNADVVVRKNSRNRPSIRRTCRITEEDDDEDENADYGDFDREDQELDDEEPEGTTIDIDEQEQQHDQGDSAEEEDDDEDVDEYFEEEEDDTQAFSPFYSSSAELIDNFGGGAGKFFNIMDFERGASGEGGFSPNGNGGPGSGDVSRTARYDSGEGDLGGGNNIMGIDSMGIANIPETMNGTTIGPSGAGGQKGGAAAGAAGQKRQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITGEYEENIRPCGVGYQCPPGYKCYGGWDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDAVGGLISDGKGKQPNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIVLVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPHDESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELDDEDKMDHETLSDEEVREMCEEEEEVDEEGMITARPRRMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGGNAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGEPCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGNIDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFKKRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNLDELDQEPEPMHRRHHTLFGSVWSSIRRHGNGTFRRSAKATASQSNGALAIGGSASAALGVGGSSLVLGSSDPAGGDYLYDTLNRSVADGVNNITRNIMQARLAAAGKLQDELQGAGSGGELRTFGESISMRPLAKNGGGAATVAGTLPPEANAINYDNRNRGILLHPYNNVYAPNGALPGHERMIQSTPASPYDQRRLPTSSDMNGLAESLIGGVLAAEGLGKYCDSEFVGTAAREMREALDMTPEEMNLAAHQILSNEHSLSLIGSSNGSIFGGSAGGLGGAGSGGVGGLGGSSSIRNAFGGSGSGPSSLSPQHQPYSGTLNSPPIPDNRLRRVATVTTTNNNNKSQVSQNNSNSLNVRANANSQMNMSPTGQPVQQQSPLRGQGNQTYSS