wanglab/gogpt-training-data huggingface dataset:
Protein: Pyrokinin-1 receptor (Q8ITC9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Receptor for the neuropeptide CAP-3/pyrokinin-1 (TGPSASSGLWFGPRL-amide). Also activated weakly by other neuropeptides terminating in the sequence PRL-amide including pyrokinin-2, Hug-gamma, and ecdysis-triggering-hormone-1. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12177421, ECO:0000269|PubMed:16054112}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cardio acceleratory peptide 2b
- Protein hugin
- Limostatin, isoform B
- Diuretic hormone receptor
- Diuretic hormone receptor
Sequence:
MSAGNMSHDLGPPRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRIIVLVWIMAIVTAIPQAAQFGIEHYSGVEQCGIVRVIVKHSFQLSTFIFFLAPMSIILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLFGKKVSKGSLNSRNNIESRRLRRALTNSSQTQRFSIESAEQPKPSIMQNPTNKPPVAAQYAMIGVQVN
Protein: E3 ubiquitin-protein ligase TRIM15 (EC 2.3.2.27) (RING finger protein 93) (Zinc finger protein 178) (Zinc finger protein B7) (Q9C019)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:34142270, ECO:0000269|PubMed:34871740}. Nucleus {ECO:0000269|PubMed:34871740}. Cell junction, focal adhesion {ECO:0000269|PubMed:25015296}. Note=Localizes to focal adhesions during the early stage of adhesion biogenesis. {ECO:0000269|PubMed:25015296}.
Interaction partners:
Sequence:
MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTLKG
Protein: Tumor protein p53-inducible protein 13 (Damage-stimulated cytoplasmic protein 1) (Q8NBR0)
Organism: Homo sapiens (Human)
Function: May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}; Extracellular side {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:14767535}. Note=Associates with unknown subcellular structures in the cytoplasm.
Interaction partners:
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein mL41
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein mL49
- Small ribosomal subunit protein mS25
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein uL10m
- Large ribosomal subunit protein bL32m
Sequence:
MAPPPPSPQLLLLAALARLLGPSEVMAGPAEEAGAHCPESLWPLPPQVSPRVTYTRVSPGQAEDVTFLYHPCAHPWLKLQLALLAYACMANPSLTPDFSLTQDRPLVLTAWGLALEMAWVEPAWAAHWLMRRRRRKQRKKKAWIYCESLSGPAPSEPTPGRGRLCRRGCVQALALAFALRSWRPPGTEVTSQGPRQPSSSGAKRRRLRAALGPQPTRSALRFPSASPGSLKAKQSMAGIPGRESNAPSVPTVSLLPGAPGGNASSRTEAQVPNGQGSPGGCVCSSQASPAPRAAAPPRAARGPTPRTEEAAWAAMALTFLLVLLTLATLCTRLHRNFRRGESIYWGPTADSQDTVAAVLKRRLLQPSRRVKRSRRRPLLPPTPDSGPEGESSE
Protein: Rearranged L-myc fusion sequence (A2A7F4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Poly
Sequence:
MADGKGDATAAAGAGAGAEAPAVAGAEVETESMARGHRPASPASGAPGLRPCLWQLETELREQEVSEVSSLSYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPFLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWVPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPILLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYITCLCSMLPSEEAIQEIAKVDCKDVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDDGKEDKQYRRSLTDQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKELFVPHVMEHVKMPPSRSHRSRKKLLLKSAQRGIYPKSPTGSLEQNPEQARGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVLGCKKFYYSKIEYQNHLSMHNVESPDGELKKSVKLEEPGAGGKQDCVDQSHLLDETEKSHSLEDHHLCPGSASAHIDTTETLKDNSDSNSSDQLSHSSSTSITEELIDTLDHSETMQDLLLSHEKVFVPSSLKDKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKPRKIKTKDLFNCLDDKHNEADKFDAEPKPSSDTNSDSPDEGPDHSIHTKCKREHQGYSPEPSICASKRPCTEDTMLELLLRLKHLSLKNSIAHGSFSGSLQGCPSSGAKSLQSVPSSISDVNLQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFRCHICQRSFTRKTHLRIHYKNKHQIGSDRATHRLLDSEKCDHEGPCSVDRLKGDCSTELGPNSNSETTQCHSKKDECSSETDLESSCEETESKISGISSPIGSHREEGEEKEGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKLFACKYKDCNKRFLCSKALAKHCSDSHNLDHIEESKVLSETESAARFSCNQPQCPAVFYSFSKLKHHLLEQHNIEGEIHSDYEIHCTLNGCGQIFSHRSNYFQHVYYRHKDYYDNLFSSQKVANERLLRSEKVCQTTQAQGLTQTQGQTQGQTQGQEQQAAKRPFNTKAKKCGLLKDKKAPITFKTRAEAIHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMNSAYLEQQLENLVVCVKYGTKIKDEPPSEVEPCVKKEESTSCESVHTENGAPGDSSVPLPNTDSTCPAEQDVGQKGCSERNPVFDTHSLLYRGTLKCNHSSETTSLEQCNIAQSSPCKIESPIPNPSGTESGTYFTDFQLPLPRIKEEPGQHSSGQENTVKNATQVPKENIRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKDDDFDDWEPSEHLTLNNSSHPSNDLTGNVVADTIVNESAPQVDIPHSSSDPPVSENLTAVPPLVVAEATAVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS
Protein: RNA-binding motif protein 24b (RNA-binding protein 24b) (E9QCG4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- RNA binding protein
- RNA binding protein fox-1 homolog 1-like
Sequence:
MHSSQKDTTYTKIFVGGLPYHTTDSSLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMADRSAAERACKDPNPIIDGRKANVNLAYLGAKPRILQPGFSFGVPQIHPTFLQRPYGDSEDDHSPLLYPPPFRQVMRIPAHYVYPQAFVQPSVVIPHVQASSSSPAAAATPYLDYSSAAYAQYTTAAAAAAAYEQYPYAASPAATAGYVTTAGTGYGYMQQPLASPAPAATAATFGQYQTQTERMQ
Protein: Nodal growth differentiation factor (D3ZGK9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Left-right determination factor
- Left-right determination factor.
- Activin receptor type-2B
- Activin receptor type-1C
- Activin receptor type-1B
- Activin receptor type-2A
- Inhibin beta E chain
- Inhibin beta B chain
- Inhibin beta A chain
- Inhibin beta C chain
Sequence:
MSVHCLPVLLLQTCWTLLHPRVATAAALPLWTRGQPSSPSPLAYMLSLYRDPLPRADIIRSLQAQDVDVTGQNWTFTFDFSFLSQEEDLVWAELRLQLLSPMDSPTKGPLTIDIFHQAKPDPEQDPADCLERVWMERITVTPSQVTFASDSTVLEVTKPLSKWLKDPRALEKQVSSQAGKCWHQSHTQPVPVTSTSVLMLYSNRPQEQRQLGGATLLWEAESSWRAQEGQLSVERSGWGRRQRRHHLPDRSQLCRRVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLEHHKDMIVEECGCL
Protein: RAB GTPase homolog H1A (F4KGG4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00037868}; Lipid-anchor {ECO:0000256|ARBA:ARBA00037868}.
Interaction partners:
Sequence:
MGDLGKGYKLVFLGDQGVGKTSIITCFMYGKFDTSYQATIGIDFLSKTTRYEDRTFRLQLWYKKLSLGDTAGQERFKSLVPSYIRDSSVAVIVYDVASKQSFINTSKWIEEVRAERGSYVIIVLVGNKTDLVNKRQVSIEEGENKAREFGALFMETSAKAGFNIKPLFCKITSALQGNEAVSWTKQEDLVDVNLKPLMFSSQANHQQESNCSC
Protein: Monomethylamine methyltransferase MtmB2 (MMA methyltransferase 2) (MMAMT 2) (EC 2.1.1.248) (Q9P9L4)
Organism: Methanosarcina barkeri
Function: Catalyzes the transfer of the methyl group from monomethylamine to the corrinoid cofactor of MtmC (MtmC1 or MtmC2).
Interaction partners:
Sequence:
MTFRKYFDCYDFYDRAKVGEKCTLDDWDLMKIPMKAMELKQKYGLDFKGEFIPTDKDMMEKLFKAGFEMLLECGIYCTDTHRIVKYTEDEIWDAINNVQKEFVLGTGRDAVNVRKRSVGDKAKPIVQGGPTGSPISEDVFMPVHMSYALEKEVDTIVNGVMTTVRGKAPIPKSPYEVLAAKTETRLIKNACAMAGRPGMGVOGPETSLSAQGNISADCAGGMTCTDSHEVSQLCELKIDLDAISVIAHYTANSDIIMDEQMPIFGGYAGGIEETTIVDVATHINAVLMSSASWHLDGPVHIRWGSTNTRETLMIAGWACATISEFTDILSGNQYYPCAGPCTEMCLLEASAQSITDTASGREILSGVASAKGVVTDKTTGMEARMMGEVARATAGVEISEVNVILDKLVALYEKNYASAPAGKTFQECYDVKTVTPTDEYMQVYDGARKKLEDLGLVF
Protein: Serine peptidase inhibitor, Kazal type 4 (A0A8I6GL16)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
KRKAACKVAQHVSQGRRGEERQVPALPSSQRRYVGIPEGRTCSCQEKLKGRGVGQGSGNSSGKWKGQELPVSAARLVFSRMPICEHMAEFPNCPRSPNLICGTDGLTYENECHLCVTRMKTKKDIQIMKDGKC
Protein: Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUb) (Coiled-coil domain-containing protein 109B) (Q810S1)
Organism: Mus musculus (Mouse)
Function: Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:23900286}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Essential MCU regulator, mitochondrial
- Calcium uptake protein 1, mitochondrial
- Calcium uptake protein 2, mitochondrial
- Calcium uptake protein 3, mitochondrial
- Calcium uniporter protein
- Mitochondrial calcium uniporter regulator 1
Sequence:
MPGALSGRRMLPSGLCLGRWQLLRTIRARGRGDPRELPSTPQVLCMKLYGNPKYHQALHYGTVEPQDEITVTYKHGLPLVTLTLPSRKERCQFVVKPMLSTVGSFLQDLQNEDKGIKTAAIITADGSEIPASTLMDTLLMTDFKLIINKLRYDIRCHKKEEPSGEHMTELENTKSLVHRLFTILHLEEIQKRRERHLMAKIDHLQEQLRPLEQVKAAIEARSEANTSGLLWAGLALLSVQGGALAWLTWWVYSWDIMEPVTFFLSFANSIVFFAYFIITRQNYTYSSLRSRQFLQFFHKKSQRRCFDVEQYNKLKEDLAEATESLESVRRSLRLRIQGEEASEKN
Protein: Immortalization up-regulated protein (Hepatocyte growth factor activator inhibitor type 2-related small protein) (H2RSP) (HAI-2-related small protein) (Q9GZP8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:11080599}.
Interaction partners:
- Kunitz-type protease inhibitor 2
- Protein phosphatase 1 regulatory subunit 14A
Sequence:
MEFDLGAALEPTSQKPGVGAGHGGDPKLSPHKVQGRSEAGAGPGPKQGHHSSSDSSSSSSDSDTDVKSHAAGSKQHESIPGKAKKPKVKKKEKGKKEKGKKKEAPH
Protein: Protein HLJ1 (P48353)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Auxilin-like clathrin uncoating factor SWA2
- Pre-mRNA-splicing factor CWC23
- Zuotin
- ER-localized J domain-containing protein 5
- Diphthamide biosynthesis protein 4
- Endoplasmic reticulum chaperone BiP
- Mitochondrial DnaJ homolog 2
- Heat shock protein SSA1
- J domain-containing protein 1
- Heat shock protein homolog SSE1
Sequence:
MSFTEDQEKIALEILSKDKHEFYEILKVDRKATDSEIKKAYRKLAIKLHPDKNSHPKAGEAFKVINRAFEVLSNEEKRSIYDRIGRDPDDRQMPSRGAASGFRGSAGGSPMGGGFEDMFFNSRFGGQRAGPPEDIFDFLFNAGGSPFGASPFGPSASTFSFGGPGGFRVYTNNRGGSPFMRQQPRSRQQQQQAEENAVNSQLKNMLVLFIIFIVLPMIKDYLFS
Protein: Prostacyclin synthase (EC 5.3.99.4) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Prostaglandin I2 synthase) (Q62969)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q29626}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Thromboxane-A synthase
- Prostaglandin G/H synthase 2
- Prostaglandin G/H synthase 1
- Prostaglandin E synthase
- Prostaglandin E synthase 3
- Prostaglandin-H2 D-isomerase
- Prostaglandin E synthase 2
- Hematopoietic prostaglandin D synthase
- Prostaglandin E synthase 3
- Prostamide/prostaglandin F synthase
Sequence:
MSWAALLGLLAVLLLLLLLLSRRRARRPGEPPLDLGSIPWLGHALEFGKDAASFLTRMKEKHGDIFTVLVGGRYVTVLLDPHSYDTVVWDLRTRLDFHPYAIFLMERIFDLQLPNFNPSEEKARMKPTLMHKDLQALTEAMYTNLRTVLLGDSTEGGSGWQEKGLLEFSYSSLLSAGYLTLYGVEASPRTHESQALDRDHSADVFRTFRQLDLMLPKLARGSLSVGDKDHACSVKSRLWKLLSPAGLASRADRSSWLESYLRHLEEMGVSEDMQARALVLQLWATQGNMGPTAFWLLLFLLKNPEALDAVHAELKRIVWQAEKPVLQMTALPQKILDSMPVLDSVLNETLRLTAAPFITREVMADLALPMADRREFSLRRGDRLLLFPFLSPQKDPEIYTEPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNQCLGKSYAINSIKQFVVLLLTHFDLELVSEDTEVPEFDLSRYGFGLMQPEEDVPIRYRTRL
Protein: Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Keratin-6-alpha) (mK6-alpha) (Keratin-6A) (K6A) (P50446)
Organism: Mus musculus (Mouse)
Function: Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
Interaction partners:
- Keratin, type I cytoskeletal 16
- Keratin, type II cytoskeletal 6B
- Keratin, type II cytoskeletal 5
Sequence:
MSTKTTIKSQTSHRGYSASSARVPGLNRSGFSSVSVCRSRGSGGSSAMCGGAGFGSRSLYGVGSSKRISIGGGSCGIGGGYGSRFGGSFGIGGGAGSGFGFGGGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPLNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQNLEPMFEQYISNLRRQLDSIIGERGRLDSELRNMQDTVEDYKSKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDDINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEDIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGPVNISVVQSTVSSGYGSAGGASSSLGLGGGSSYSYSSSHGLGGGFSAGSGRAIGGGLSSSGGLSSSTIKYTTTSSSKKSYRQ
Protein: Major facilitator superfamily protein (Q9SW40)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGFGTSSSSSSSSALKWLGFVTAVWVQSISGNNYTFSNYSGALKSLMNLTQLELNSLSVAKDVGKAFGILAGLASDRLSTPVILLIGSFEGLLGYGVQWLVVSRTIQPIPYWQMCVFLCMGGNSTTWMNTAVLVTCIRNFRRNRGPVSGILKGYVGLSTAIFTDLCNALFSSDPASFLVLLSVVPFAVCLTAVFFLREIPPSTTFAEDNEESKYFAVFNIVAVVVAVYLQSYDIIGIKTGAFSIAFASILLILLASPVAVPFHAFIRSKVHDEQDVEGRIDEPLLRSGSEIEVEETIVGAAAAADNELPPSLKPLSNEEEENHGTIVTTEKKRPVLGEEHTIMEAMLTVDFWVLFVSFLCGVGTGLAVMNNMGQIGLALGYTDVSIFVSMTSIWGFFGRILSGTISEHFIKKAGTPRPLWNAAAQIIMAVGYLLMALALPGSLYIGSMVVGVCYGVRLAITVPTASELFGLKYYGLIYNILILNMPLGSFLFSGLLAGLLYDAEATPTPGGGNTCVGAHCFRIVFIVMAFASIIGVGLDLLLAYRTKGIYAKIHASKKTKKSGGNLR
Protein: Outer mitochondrial membrane protein porin (AFU_orthologue AFUA_4G06910) (Q5B4X8)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Translocase of outer membrane 40 kDa subunit
- Mitochondrial import receptor subunit TOM20
- Transmembrane GTPase Fzo1, putative
- Mitochondrial outer membrane translocase receptor
- ZZ type zinc finger domain protein
- Prohibitin
- Mitochondrial Rho GTPase 1
- Mitochondrial outer membrane protein
- Mitochondrial import receptor subunit tom22
- Autophagy protein 5
Sequence:
MAAPAAFSDIAKAANDLLNKDFYHGSAASLEVKSKAPNGVTFNVKGKSAHEGPIAGSLEAKYVDAPTGLTLTQAWTTANALDTKLELDNNIAKGLKAEIITQYLPAKQSKGAKLNLHFKQPNLHARAFFDLLNGPSANFDAVLGHEGFLVGAEGGYDVQKAAITKYSAAVGYSVPQYSAAIQAANNLTVFSASYYHRVNAQVEAGAKATWDSKTGNSVGLEVASKYRLDPSSFAKVKINDRGIAALAYNVLLRPGVTLGLGASFDTQNLNQAAHKVGASFTFEA
Protein: Ubiquitin-conjugating enzyme E2, putative (EC 6.3.2.19) (Q584B6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- propanoyl-CoA C-acyltransferase
- Nonspecific lipid-transfer protein, putative
- HECT-type E3 ubiquitin transferase
- E3 ubiquitin-protein ligase TRIP12
- Ubiquitin-protein ligase, putative
- Ubiquitin-protein ligase, putative
- Ubiquitin-conjugating enzyme E2, putative
- Ubiquitin-conjugating enzyme, putative
- Polyubiquitin, putative
- Ubiquitin-activating enzyme E1, putative
Sequence:
MKRIAKDLNVLKTDISRSAPVVSLIAAVESENVYQWHIVARAPADSIYSSNSDEAQHKKKNAYRLSVIFTDDYPDKPPKVSFITNIYSPLVGEKGDVCERLTEKDWTPDQRATNVIMRVLNEVFSGYKNNDDYDLNHDARRCLKEEPEVFEKRAQCPF
Protein: Uncharacterized protein (Q4GYV2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEQCCGAAAITDAVDLRDVITSSRKRRRVDVGECEELWQQINKILQETFTEPQMVVQRNEKEMDTITVTILAQLYRVLRDCWCFSGDPYDLFEPVTNLHDVTKRVLMTSGGYVLTPDSQNLLLGSDANMAYVGILLSRVYRVLVGFGHLHCIPPEDAGITNLENEVCIVLRNRQGLTGVESDLIKEICSTLRSQLQDPTGTAVALFEEWPLLETSEFARLVADFNMKFIEFLPFLPTEGSGGAAFCLIPSNNYDTVWGRVVSCGSCWVAGKMCAQSFLVSPSGPLIVHLLRCQRKDGIPYDGGAHVTVSGNEDEVILREWLRQRLWTPQPTVIVQWWRANVLSSCVDFPSSLISEVDNGPGNHKFERCWPQFIDGAADCLPAVWVRGLQVVSSVKVDVECCVCRMVSCPW
Protein: cDNA, FLJ96906, highly similar to Homo sapiens solute carrier family 17 (anion/sugar transporter), member 5 (SLC17A5), mRNA (B2RE38)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MRSPVRDLARNDGEESTDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSPQKSVPWVPILKSLPLRAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLTPDNTVGEWQTVFYIAAAINVFGAIFFTLFAKGEVQNWALNDHHGHRH
Protein: Fanconi Anaemia group E protein C-terminal domain-containing protein (Q54WG5)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MGIKFNLYQIIFKILLNGFSKKQKDLYENSTTNGGSEFNDEIIEEFSSQELKERGQLKQKDKSTPSSSTNIESLQLLQNILISNEFIWEWEDFFQFLNSTEYESNHHNYHNNNIIETRNSSNKFYILTFKEELQIELLNWFLVLLNSFDSENTPSTILVIPKLSLKNWLLNTYIQDLIGYSTYSSNHFISFIVDSLLSTIDFHLDISINQNYENRKLSNNNNNNNNNNNNNNNNNNNNINNINNDNNNQSFNLYYPFTTFYKKDIDDEINFVIDSMNNSITKKEKDQQQQEHQEPFNSYLKGFIKSQFQNKWCGSLLTPYKALQQQQQQSIGNQDIEGINNDQIIDLMNDDQDEDESFNQHLQDWSIQFQTLLPEFTNFTEKEGITDSSHLFNPFTFSQTDQNSLSQGSQSNKSQENNENHSKTIISKAATITTAEIATSKTKDQKEKIKATSKTTTTTTTTTTTTATTSSKQLENEEISSILAIHSFFTSGEALKSISMVTNFDEDNFDPLTQNSSTNVSSISSLIKPLLSISNINEAIRLLEVHTYTEDKFISFFKEIISLDFSYLSIYQYFSLLILPKIRELKEIGRGMVDLLTECFLKHQSAFIQSIMVPLILERPTEFQNHHLNLVKKLISHKDISLDIKTQFFSALVSSTLNQTQFTWNQNIISVFSTLIGLKLVLNEKIITDFIDNLLLQSKLLSKDSNFFNLVHRFMSSYIKNLKQFENKLNQVVSNIDLPTAKALVAILSKIKSS
Protein: Secreted thaumatin-like protein cetA (Conidial-enriched transcript protein A) (C8VIP3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Secreted thaumatin-like protein that, with calA, plays an essential role in early conidial germination with a possible role in cell wall remodeling.
Subcellular location: Secreted {ECO:0000269|PubMed:16376592, ECO:0000269|PubMed:17703972}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17703972}. Secreted, cell wall {ECO:0000269|PubMed:17703972}. Note=Present in the cell walls of the germinating conidia but not in the germtubes (PubMed:17703972). {ECO:0000269|PubMed:17703972}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit tim9
- Mitochondrial import inner membrane translocase subunit TIM22
- NADH-ubiquinone oxidoreductase 213 kDa subunit
Sequence:
MMFTKALVAATLATLTAALPQPTVVRREGGDAGVTIVNNMDSDVYAWSVTDGVSKMHTLSSGGGSYTENFQANPNGGGVSIKLSTHQDQTDVLQFEYTKSGETIFWDMSCIDMDRAASTFTKNGFDVSPSQTSGDCPAVNCHAGDTSCAEAYLQPKDDHATHGCPIDTSFTLTLGA
Protein: Apolipoprotein L domain-containing protein 1 (Vascular early response gene protein) (Q6B959)
Organism: Rattus norvegicus (Rat)
Function: May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q96LR9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96LR9}. Cell junction {ECO:0000250|UniProtKB:Q96LR9}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:Q96LR9}. Note=Localized to Weibel-Palade bodies, secretory granules characteristic of vascular endothelial cells. {ECO:0000250|UniProtKB:Q96LR9}.
Interaction partners:
- RNA helicase
Sequence:
MEKWTAWEPQGADALRRFQGLLLDRRGRLHCQVLRLREVARRLERLRRRSLAANVAGSSLSAAGALAAIVGLSLSPVTLGASLVASAVGLGVATAGGAVTITSDLSLIFCNSREVRRVQEIAATCQDQMRELLSCLEFFCQWQGRGDRQLLQSGRDASMALYNSVYFIVFFGSRGFLIPRRAEGATKVSQAVLKAKIQKLSESLESCTGALDELSEQLESRVQLCTKAGRGHNLRNSPDLDAALFF
Protein: Syncytin-2 (Endogenous retrovirus group FRD member 1) (Envelope polyprotein) (HERV-FRD) (HERV-FRD_6p24.1 provirus ancestral Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)] (P60508)
Organism: Homo sapiens (Human)
Function: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process.
Subcellular location: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Surface protein]: Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM. {ECO:0000250|UniProtKB:Q9UQF0}.; SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium-dependent lysophosphatidylcholine symporter 1
- Angiotensin-converting enzyme 2
- Plasminogen
- Fibronectin
- Complement factor H
- Cadherin-1
- Albumin
- Neutral amino acid transporter B
- Hepatic sodium/bile acid cotransporter
- Outer mitochondrial transmembrane helix translocase
Sequence:
MGLLLLVLILTPSLAAYRHPDFPLLEKAQQLLQSTGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKGLMRPANSLLSTVKQDFPDIRQKPPIFGPIFTNINLMGIAPICVMAKRKNGTNVGTLPSTVCNVTFTVDSNQQTYQTYTHNQFRHQPRFPKPPNITFPQGTLLDKSSRFCQGRPSSCSTRNFWFRPADYNQCLQISNLSSTAEWVLLDQTRNSLFWENKTKGANQSQTPCVQVLAGMTIATSYLGISAVSEFFGTSLTPLFHFHISTCLKTQGAFYICGQSIHQCLPSNWTGTCTIGYVTPDIFIAPGNLSLPIPIYGNSPLPRVRRAIHFIPLLAGLGILAGTGTGIAGITKASLTYSQLSKEIANNIDTMAKALTTMQEQIDSLAAVVLQNRRGLDMLTAAQGGICLALDEKCCFWVNQSGKVQDNIRQLLNQASSLRERATQGWLNWEGTWKWFSWVLPLTGPLVSLLLLLLFGPCLLNLITQFVSSRLQAIKLQTNLSAGRHPRNIQESPF
Protein: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG (Glucose-inhibited division protein A) (P0A6U3)
Organism: Escherichia coli (strain K12)
Function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17062623}.
Interaction partners:
- tRNA modification GTPase MnmE
- Ribosomal RNA small subunit methyltransferase G
- tRNA-specific 2-thiouridylase MnmA
- Protein MioC
- Chromosomal replication initiator protein DnaA
- tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC
- Ribonuclease P protein component
- ATP synthase subunit c
- Membrane protein insertase YidC
- Adenine phosphoribosyltransferase
Sequence:
MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
Protein: Probable reductase (P95146)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Ferredoxin reductase
- Nitrite reductase small subunit
- Endonuclease
- Rubredoxin
- Rubredoxin
- Conserved protein
- Uncharacterized protein Rv2633c
- Putative Rieske 2Fe-2S iron-sulfur protein Rv3818
- Glutamate synthase large chain
Sequence:
MASSTTFVIVGGGLAGAKAVEALRRSDFGGRIILFGDEEHLPYDRPPLSKEFLAGKKSLSDFTIQTSDWYRDHDVDVRLGVRVSSLDRSAHTVELPDGAAVRYDKLLLATGSAPRRPPIPGSDAAGVHYLRSYNDAVALNSVLVQGSSLAVVGAGWIGLEVAASARQRGVDVTVVETAIQPLLAALGEAVGKVFADLHRDQGVDLRLQTQLEEITAADGKATGLKMRDGSTVAADAVLVAVGAKPNVELAQQAGLAMGEGGVLVDASLRTSDPDIYAVGDIAAAEHPLLGTRVRTEHWANALKQPAVAAAGMLGRPGEYAELPYLFTDQYDLGMEYVGHAPSCDRVVFRGNVAGREFLSFWLDGDSRVLAGMNVNVWDVVDDVKGLIRSGNPVDVDRLVDPQWPLADLTTN