wanglab/gogpt-training-data huggingface dataset:
Protein: Replication factor C subunit 5 (Replication factor C5) (Activator 1 40 kDa subunit) (P38251)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of ATP-dependent clamp loader (RFC and RFC-like) complexes for DNA clamps, such as the POL30/PCNA homotrimer and the checkpoint clamp DDC1:MEC3:RAD17 complex. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. Component of the replication factor C (RFC or activator 1) complex which loads POL30/PCNA and acts during elongation of primed DNA templates by DNA polymerase delta and epsilon. RFC has an essential but redundant activity in sister chromatid cohesion establishment. Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA. Component of the RFC-like RAD24-RFC complex which loads the checkpoint clamp DDC1:MEC3:RAD17 complex and is involved in DNA repair pathways. Component of the RFC-like ELG1-RFC complex which appears to have a role in DNA replication, replication fork re-start, recombination and repair.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Sister chromatid cohesion protein DCC1
- Replication factor C subunit 3
- Telomere length regulation protein ELG1
- Replication factor C subunit 1
- Checkpoint protein RAD24
- Proliferating cell nuclear antigen
- Replication factor C subunit 2
- Chromosome transmission fidelity protein 18
- Replication factor C subunit 4
- Chromosome transmission fidelity protein 8
Sequence:
MSLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKTRCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMGNNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDAQAALRRTMEKYSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTILSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESMALNNELALKSSSPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIILKELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMCCLD
Protein: Protein PUN1 (Plasma membrane protein up-regulated during nitrogen stress 1) (Q06991)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Contributes to the wild-type cellular response to nitrogen stress through signaling pathways that regulate the expression of genes involved in amino acid biosynthesis. Required for wild-type filamentous growth, cell growth, and cell-cell adhesion.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:18799621, ECO:0000269|PubMed:20228058}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:18799621, ECO:0000269|PubMed:20228058}. Note=Localizes to punctate patches in the plasma membrane that show extensive colocalization with SUR7.
Interaction partners:
- Cell wall biogenesis protein NCW2
- Uncharacterized plasma membrane protein YNL194C
- SUR7 family protein FMP45
Sequence:
MRNFFTLFFAAIFSLGALILAIVACAGSTKNYSPINKIYCAELDLSQMKVSTVLPSLSSATLSSLGLPSYINIGLWSYCTVDSSHNIQSCSSPHGIQNFNLSSLVYDNINNNEALELMDSVASVVLPEKLKSKMTYYNNLVKCMFITILIGIVLTFVNLVFNVLRWIIHIRPLTWFGAFFSFFAFAALLVSIGSCLGTYSYIKYILKHNYSDYGISMSIGRNYQGLMWGAVVGALLNFILWCSVRSRPTVIYANAPIEEKPLI
Protein: RNA helicase (EC 3.6.4.13) (A0A2R8YDT5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Protein: Sterol regulatory element-binding protein 1 [Cleaved into: Processed sterol regulatory element-binding protein 1] (Q9UUD1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane. Low oxygen or sterol conditions promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes required for adaptation to anaerobic growth.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P36956}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P36956}.; SUBCELLULAR LOCATION: [Processed sterol regulatory element-binding protein 1]: Nucleus {ECO:0000269|PubMed:16537923}. Note=Accumulates at promoters of the target genes (PubMed:16537923). {ECO:0000269|PubMed:16537923}.
Interaction partners:
- Sterol regulatory element-binding protein cleavage-activating protein
- Prolyl 3,4-dihydroxylase ofd1
- Rhomboid-type serine protease 2
- UBX domain-containing protein 10
- Negative regulator of ofd1
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- C-4 methylsterol oxidase erg25
- ERAD-associated E3 ubiquitin-protein ligase hrd1
- Probable oxygen-dependent coproporphyrinogen-III oxidase
- C-22 sterol desaturase ERG5
Sequence:
MQSSIPSVSVSVASPAMETPTKASPDSKSPNSVGAIPSSSPLASSTKASTSTPFVENCSNLLCDLASIVEDSPPTLTNTSLSPHSFSLSDMESSMSNWLNPFAFDNTMNSAPPLFTSTNMGSPNSLENSTNPLLSNCGSPNSFQNETFTGPSLNEFDADDKIQRQMKILHSVDTIDPSTVQNYPSADMSNPEVKLKTEEIITPMDTTCKPEPSAKKIKLSPSSEDSCSIPETLPFSAPKSRGSLSPSETPDFVAGPGGKPKKTAHNMIEKRYRTNLNDRICELRDAVPSLRAAAALRCGNSLDDEDLGGLTPARKLNKGTILAKATEYIRHLEAKNKELQKTNKQLSDRLAFYEDPSMAPPSNDTRAVNSVNVVSSSDYSVHQSSRPNLTQRAFTSPTLNTMGRTALNGMVGLGLFNYFGNDSSQSVYGLFALPPFLMSPFTGTVLFNMLKIGVVLLGLFYLLHDNSLFKGFKGEKKSKVSTRSSMSPSSILFRKTVFEKYCLLDHSTSTISLFFGLLIFTLKSAYGYLTHRLSALYTSSENWVYSEQQLAEVRNMEKLLDAQLMGGDAKVDRLRLLMVFASSFSLPPSSHTCALQAMYCQLIFSNTSVPSAIVSKCVAFFWNAAKKQHSKSSVHAELRELPECTANLIENSHADDVFSPNMVERLWVLAKCTRDSAQMSDSIISSLSDVLVLSPLEVLASWYAADLLDALLMESLSRKVEISEIEEIISLCPKNSSIIRHALLAKLVLFPENTADSLNEVLAAYKNTLDLCSQDKRKQSSVLKINLSKLFTLHSCLSLALQRLGYGDVSKRMYQEIFVPDSDADITPLSFIISWTALNTFAPICTSPKENDVVEKMAMYVRTAIGTLKIQDLKLSRKLINSCIDIGSRLQEDLGYVSSA
Protein: Pyruvate dehydrogenase [ubiquinone] (EC 1.2.5.1) (Pyruvate oxidase) (POX) (Pyruvate:ubiquinone-8 oxidoreductase) (P07003)
Organism: Escherichia coli (strain K12)
Function: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone (By similarity). The main pathway for acetate production during stationary phase.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00850, ECO:0000269|PubMed:365232, ECO:0000305|PubMed:5336022}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00850, ECO:0000269|PubMed:365232, ECO:0000305|PubMed:5336022}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_00850, ECO:0000269|PubMed:365232}.
Interaction partners:
- Acetate kinase
- D-lactate dehydrogenase
- Formate acetyltransferase 1
- Acetyl-coenzyme A synthetase
- Phosphoenolpyruvate synthase
- NADP-dependent malic enzyme
- PFL-like enzyme TdcE
- NAD-dependent malic enzyme
- Quinone-dependent D-lactate dehydrogenase
- Probable pyruvate-flavodoxin oxidoreductase
Sequence:
MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLPGDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDKALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMKLPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELAKTNWLR
Protein: Ras-related protein Rab-3 (Q95QV3)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU367096}; Lipid-anchor {ECO:0000256|RuleBase:RU367096}; Cytoplasmic side {ECO:0000256|RuleBase:RU367096}.
Interaction partners:
Sequence:
MNNQQAAIASARSRMAAGGQPQGATPGQPDQNFDYMFKLLIIGNSSVGKTSFLFRYCDDSFTSAFVSTVGIDFKVKTVFRGDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNSVQDWCTQIKTYSWENAQVVLVGNKCDMDSERVVSMDRGRQLADQLGLEFFETSAKENINVKAVFEKLVEIICDKMAESLDKDPQQQPKGQKLEANPTQKPAQQQCNC
Protein: Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM2 (EC 2.7.11.1) (Protein BARELY ANY MERISTEM 2) (Q9M2Z1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Necessary for male gametophyte development, as well as ovule specification and function. Involved in cell-cell communication process required during early anther development, and regulating cell division and differentiation to organize cell layers. Required for the development of high-ordered vascular strands within the leaf and a correlated control of leaf shape, size and symmetry. May regulate the CLV1-dependent CLV3-mediated signaling in meristems maintenance.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20626648}; Single-pass type I membrane protein {ECO:0000269|PubMed:20626648}.
Interaction partners:
- Protein IQ-DOMAIN 3
- IQ-domain 21
- Duplicated homeodomain-like superfamily protein
- Probable sphingolipid transporter spinster homolog 1
- IQ-domain 24
- Probable protein phosphatase 2C 64
Sequence:
MKLLLLLLLLLLLHISHSFTVAKPITELHALLSLKSSFTIDEHSPLLTSWNLSTTFCSWTGVTCDVSLRHVTSLDLSGLNLSGTLSSDVAHLPLLQNLSLAANQISGPIPPQISNLYELRHLNLSNNVFNGSFPDELSSGLVNLRVLDLYNNNLTGDLPVSLTNLTQLRHLHLGGNYFSGKIPATYGTWPVLEYLAVSGNELTGKIPPEIGNLTTLRELYIGYYNAFENGLPPEIGNLSELVRFDAANCGLTGEIPPEIGKLQKLDTLFLQVNAFTGTITQELGLISSLKSMDLSNNMFTGEIPTSFSQLKNLTLLNLFRNKLYGAIPEFIGEMPELEVLQLWENNFTGSIPQKLGENGRLVILDLSSNKLTGTLPPNMCSGNRLMTLITLGNFLFGSIPDSLGKCESLTRIRMGENFLNGSIPKELFGLPKLSQVELQDNYLTGELPISGGGVSGDLGQISLSNNQLSGSLPAAIGNLSGVQKLLLDGNKFSGSIPPEIGRLQQLSKLDFSHNLFSGRIAPEISRCKLLTFVDLSRNELSGDIPNELTGMKILNYLNLSRNHLVGSIPVTIASMQSLTSVDFSYNNLSGLVPSTGQFSYFNYTSFVGNSHLCGPYLGPCGKGTHQSHVKPLSATTKLLLVLGLLFCSMVFAIVAIIKARSLRNASEAKAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGTMPKGDLVAVKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWNTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELITGKKPVGEFGDGVDIVQWVRSMTDSNKDCVLKVIDLRLSSVPVHEVTHVFYVALLCVEEQAVERPTMREVVQILTEIPKIPLSKQQAAESDVTEKAPAINESSPDSGSPPDLLSN
Protein: Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH 1) (EC 1.2.1.12) (Triose-phosphate dehydrogenase 1) (P00360)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11502169}.
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Glyceraldehyde-3-phosphate dehydrogenase 3
- Phosphoglycerate kinase
- Triosephosphate isomerase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Actin
- Transaldolase
- Enolase 1
- Glucose-6-phosphate 1-dehydrogenase
Sequence:
MIRIAINGFGRIGRLVLRLALQRKDIEVVAVNDPFISNDYAAYMVKYDSTHGRYKGTVSHDDKHIIIDGVKIATYQERDPANLPWGSLKIDVAVDSTGVFKELDTAQKHIDAGAKKVVITAPSSSAPMFVVGVNHTKYTPDKKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLEKEATYDQIKKAVKAAAEGPMKGVLGYTEDAVVSSDFLGDTHASIFDASAGIQLSPKFVKLISWYDNEYGYSARVVDLIEYVAKA
Protein: Erdr1 protein (Q6PED5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSLPCPRDARTHGRTPQGRKPAPTAPPHPPQHTGHTRAPRPPRHTRHTRHTRQAGQAHASAGPAPATQTRTSRRGQDVHPPRSRCMCHRPSPRWTDGRTRARRQRPPVTAAAHSDVTHESTHVEADAVVKMSLPSPQDGRTDSTR
Protein: Protein SPO16 homolog (Synaptonemal complex reinforcing element) (Q3KQP7)
Organism: Mus musculus (Mouse)
Function: Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates.
Subcellular location: Chromosome {ECO:0000269|PubMed:30746471, ECO:0000269|PubMed:30949703}.
Interaction partners:
Sequence:
MAMDERRGKERVQWTTTIIISSSLKSYEIATALENRSHKVRYSDTLESGSIVFSLSGVAFLLMDAKECMTSAEEIFVTKIEKFINIHQNSFLVLFAPLHGPEEWSLMFRIHQRFLGSNLRILPVHNTVNALDLMCTIAKTTSKPHIDSICYRMITTKAYIIEQSPVWRTLQKIKLSSDSVSADSGE
Protein: GM2 ganglioside activator (Q6IN37)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Beta-hexosaminidase subunit alpha
- Beta-hexosaminidase subunit beta
- Prosaposin
- Oxysterol-binding protein
Sequence:
MRRVPLLLVLGLLFVLGLLFAGPVAPSRLISKRPSQLGGFSWDNCDEGKDPAVIKSLTLQPDPIVVPGDVIVSAEGKTSIPLTSPQKVELTVEKEVAGFWVKIPCVEQLGSCTYENVCDLIDQYIPPGETCPEPLHTYGLPCHCPFKEGTYSLPSSNFTVPDLELPSWLSTGNYRIQSILSSGGKRLACIKIAASLKGK
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q38CQ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MRLISLEVAAFIVLRSTKPANIADAANKAEHAALCNFISMAGRVIAVPTVQPLDTENYAYIQQLNFALGDQQWQEKFYKNSDRKGVKDTAAEAGITGEGAADMWADLKKAAEALKSDSQNPLLKELEEMKLTAAARRLAKAELESLTNESREIKKMYPDPPKNVDYENNNPKSKLLAALLGAGNADVGTATGQKAVGAAATATRQATCTAGEKTTARPASALAMLACVCQSSGTAVTNFICTEKAKDSNAWTGNAYPHDTGLRHIGKSCPKARDDPVTTTELETALNNLLALIHTDGTHEYLGAYVQTGCDGTSPNGICVQFPDLATSAPEVATRDTWLATVAEIIQNLKILENNQAKAEYVNNQIKDKKHRALAALRRSKAIAGAIQVPTPQTAQKPKIGVNTRCEAHNKSKAACLGAKCKWGGQKDDDGPCSPSEEQAAEEEKETAGEAVTGTATEKCKGKLEPECTKAPEFKWENSACKDSIFLVNKKFALSMDAAFLSLVVFRYFIILAF
Protein: FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Q5ATN7)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular location: Endoplasmic reticulum {ECO:0000255|PROSITE-ProRule:PRU10138}.
Interaction partners:
- Vacuolar membrane protein
Sequence:
MRVPIITTLLTLALTGLSQAASLGVETTHGVECNRKTTKGDTVKMHYRGTLAEDGSQFDASYDRGTPFKFKLGAGRVIKGWDEGLLDMCVGEKRTLTIPPEYGYGDRGIGPIPGGATLIFQTELLEIEGVPKDEL
Protein: MEK1 interacting protein 1 (Q557I6)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MDSQTSQDIPEILNDIFELMDRQIDEENKQQKDDKNKTIAHGTSQLVQHENPQEDFAFGVKNPIQQNEEEKKNEEEKQNEEVKQNEEEKQNEEVKQNVEEKQENRENEQHNEENEQQNGEQNKEEEQQSQQSQQSQQSQQSQQIDLNIKKEGEKQNQRQSSRQVVIIDLSDDDEDDEDDDGENDNDKPTPISNTETTETSTTTTTTTTNVNNQNNNQDKEVVDLTLSPPQSPVLVLTATRLANNNNNHNNDRNNNSNNNSNNRFLNRQANDFTFFRNNSFFNSRTQHQPPPPPSQQQFPIVLNIFNNHSGSAVGNGPIGNNGNGGNSLKKRKHYHNFDTDDDDDDDDDDDDDEDDDDEDDDDDDVHFDRRNQFPISPEDLFDENIDISFGFGGRDRNSDSSDDSFFRPTNRQSLVGTNRSAVRNNNNSNNNNTTATASIQTTKPEVIHILEKQGNSSLSSISENSELWKLQKEMEKENESKKAIDTQSNGGDKKSKNLECPICFEDTKPYVSTLCGHIFCSDCIVNALKKKKSCPVCNAKLHGKKPYHPIYI
Protein: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC 5.4.2.11) (O51602)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Interaction partners:
- Phosphoglycerate kinase
- Enolase
- Triosephosphate isomerase
- Glucose-6-phosphate isomerase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate 1-dehydrogenase
- Ribose-5-phosphate isomerase A
- Glyceraldehyde-3-phosphate dehydrogenase
- Pyruvate kinase
Sequence:
MYKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRANDTLNIILRELGQSYISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPPMSLDESDDRHPIKDPRYKHIPKRELPSTECLKDTVARVIPYWTDEIAKEVLEGKKVIVAAHGNSLRALVKYFDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIKKAMESVASQGKLK
Protein: AT3G20230 protein (Ribosomal L18p/L5e family protein) (Q9LJX6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL18c
- Expressed protein
- Large ribosomal subunit protein bL28c
- Large ribosomal subunit protein uL3c
- RNA-binding
- Pentatricopeptide repeat-containing protein At1g02150
- Small ribosomal subunit protein cS23y
- Pentatricopeptide repeat-containing protein At5g46580
- Pentatricopeptide repeat-containing protein At2g18940
- Pentatricopeptide repeat-containing protein At3g53700, chloroplastic
Sequence:
MSCLISSTCSLVPFDSNLTRSNRFTKLGSAVSWQSSFPKLSIEIGSVISSPIVKKDSFVQAAWTRRSRGEAAKRPNRKSWKQRTDMYMRPFLLNVFFSRKFIHAKVMHRPTSKVISVATTNARDIRTNIPSLVDNEACRLIGKLIAERSMEADVYAVSYEPRKGERIEGKLGIVIDTIKEHGIIFVP
Protein: Probable circularly permuted 1,3-beta-glucanase P23A10.11c YJL171C (EC 3.2.1.39) (Q9P7X4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Probable secreted beta-glucosidase C2G2.17c
- Fluoride export protein 2
- Putative amidase PB8B6.03
- Putative uncharacterized protein C23C4.04c
- Uncharacterized protein C685.08
- Uncharacterized mitochondrial membrane protein C800.14c
- Uncharacterized protein PB1A10.16
- Uncharacterized protein C16G5.19
- Putative uncharacterized protein C27E2.12
- Putative lysine N-acyltransferase C17G9.06c
Sequence:
MIAKSFIASFLFLCFAFSGVKADGCSEENGYYYCNQASEVEFTNVGYSSTYNEITNMDTSSCSCSSTPKSYGGNLAPFDEEFSFHFRGPIELKRFAVYYPDTSNALSSLRKRSNNQHMKRHPHHKRDDVIDSTLTVYETVMYTTAVYGDSATTPAASEAQASSDILSSLASLSSASTDNLAASVTPTTVAASVASSVDTDSASATISSVVDSATSSVSTVIPSSIISAAPPDSASESTPASTSYASSTTSATSTSTTSGSSGSSDWGRSSFYEADSGTSDNIVFLNNMGGSAGSGVWSSCFGNSLSFAASNGVDGASSSQVLENILVASDKEFSIWTATECNNDCGYYLPGIPAYHGFSGAKLVLMEFIMPHDSSSSYNQDMPAIWSLNAQIPRTLQYGNADCSCWTTGCGEFDIFEVLSTGNEKMIPTLHGSQGSSNGNGGGAGSSDYFARPTSSSMIGAVIYDTSSSGIYIIDVTDQNVSFDSTYSASDVDAWLQSGATIVQLSS
Protein: Protein dpy-30 homolog (B8JMZ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Retinoblastoma-binding protein 5.
- WD repeat domain 5
- WD repeat-containing protein 82
- Histone-lysine N-methyltransferase SETD1B-A
- CXXC finger protein 1b.
- Histone-lysine N-methyltransferase SETD1A isoform X1
- SET domain-containing 1B, histone lysine methyltransferase b.
- CXXC finger protein 1a.
- Ubiquitin-ribosomal protein eL40 fusion protein
Sequence:
MADEHTDAGESMEGHTPVPENPHAEYGLTENIQRIAENEKTAEKVGKQKVDPQTLQTLPTRAYLDQTVVPILLQGLSVLAKERPPNPIEFLAAFLLKNKSQFEERN
Protein: F420-dependent formate dehydrogenase subunit alpha (EC 1.17.98.3) (P06131)
Organism: Methanobacterium formicicum
Function: Catalyzes the oxidation of formate.
Interaction partners:
- F420-dependent formate dehydrogenase subunit beta
- Formylmethanofuran dehydrogenase subunit A FwdA
- Hydrogenase iron-sulfur subunit
- CoB--CoM heterodisulfide reductase iron-sulfur subunit A
- Formylmethanofuran dehydrogenase subunit B FwdB
- CoB--CoM heterodisulfide reductase subunit B
- CoB--CoM heterodisulfide reductase subunit C HdrC1
- formylmethanofuran dehydrogenase
- Formylmethanofuran dehydrogenase subunit C
- Formylmethanofuran dehydrogenase subunit G FwdG
Sequence:
MDIKYVPTICPYCGVGCGMNLVVKDEKVVGVEPWKRHPVNEGKLCPKGNFCYEIIHREDRLTTPLIKENGEFREATWDEAYDLIASKLGAYDPNEIGFFCCARSPNENIYVNQKFARIVVGTHNIDHCARLCHGPTVAGLAASFGSGAMTNSYASFEDADLIFSIGANSLEAHPLVGRKLMRAKMNGAYFIVADPRYTPTAKQADQYIPFKTGTDVALMNAMMNVIISEGLEDKEFIEKRTKNYEELKEVVSKYTPEMAEEITQVPADVIRDIAIKYAKADKAAIVYSLGITEHSHGVDNVMQTANLAMLTGNIGRLGTGVNPLRGQNNVQGACDMGALPTDYPGYRKVADQEVMEDVTCTWGCSDLGCEPGLKIPEMIDAAAKGDLKVLYITGEDPVISDPDTHHVEEALNNLDFFVVQDIFMTDTAEFADVVLPAACWAEQEGTFTNGERRVQLIRKAVDAPGESKYDWEIFCDLAKKMGADPEMFTYESAQDIFEEVRTVTPQYAGMNRERLDRPEALHWPCPSEDHPGTAMMHIEKFAHPDGLGIFMPLEEQGPMETPDDEYPLILTTTRLLFHYHAAMTRRAATLDREVPTGYVEINTEDAAELGIANKEKVKVKSRRGEIEIAARVTDDIVKGIVNIPMHFRECSANILTNAAAIDPKSGMPEYKACAVAISKMEGSK
Protein: Large ribosomal subunit protein eL36 (60S ribosomal protein L36) (P49181)
Organism: Caenorhabditis elegans
Function: Component of the large ribosomal subunit.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9Y3U8}. Cytoplasm {ECO:0000250|UniProtKB:Q9Y3U8}. Note=Detected on cytosolic polysomes. {ECO:0000250|UniProtKB:Q9Y3U8}.
Interaction partners:
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein uL10
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein eL27
- Small ribosomal subunit protein uS11
- Ubiquitin-ribosomal protein eL40 fusion protein
- Large ribosomal subunit protein eL28
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein eS6
Sequence:
MSGPGIEGLAVGLNKGHAATQLPVKQRQNRHKGVASKKTKIVRELVREITGFAPYERRVLEMLRISKDKRALKFLKRRIGTHRRAKGKREELQNVIIAQRKAHK
Protein: POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3) (Q01860)
Organism: Homo sapiens (Human)
Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Subcellular location: Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. {ECO:0000250|UniProtKB:P20263, ECO:0000269|PubMed:18191611, ECO:0000269|PubMed:19274063, ECO:0000269|PubMed:23024368}.
Interaction partners:
- Catenin beta-1
- Transcription factor SOX-2
- Homeobox protein NANOG
- Sal-like protein 4
- Krueppel-like factor 4
- Protein lin-28 homolog A
- WD repeat-containing protein 5
- Transcription factor SOX-17
- PR domain zinc finger protein 14
- POU domain, class 5, transcription factor 1B
Sequence:
MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
Protein: methionine--tRNA ligase (EC 6.1.1.10) (Q8IJ60)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Methionyl-tRNA formyltransferase, putative
- methionine--tRNA ligase
- leucine--tRNA ligase
- leucine--tRNA ligase
- arginine--tRNA ligase
- glutamate--tRNA ligase
- glutamate--tRNA ligase
- glutamine--tRNA ligase
- Isoleucine--tRNA ligase, putative
- isoleucine--tRNA ligase
Sequence:
MMKPLNMILYPHKFFLNTVKCMLAAHIYNFNVELSEDFLYTRTFDIEKSLIINKKPLLIYENNYVSSTKAICFLFHRLRNKSKKPFDENLSYYLGWLEWSDLLEKHIEVLNKKNIIESLDELELYLKENKNKNKNFINNDDEKDENKLSLADIFVYTSLKHSCIEICKESWVHINEYIEKINNLQEIQNVIKNVEEIYKYKNIYSVFISKIHDKNVNEYLKNETFYITTAINYVNGDPHIGHAYEIVLADAIARYHKIIGRDTFFTTGADEHGLKIANQAAKNNMTPKELCDKNVLKFQNLNKLLYVEDDYYVRTTRDSHKKIAQEVWDKCEKNGDIYLGEYEGWYNVREETYVPENEAKLMNYIDPLNNIKLEKMKEPSYFFKMSKYQDKLIEYIQSNPDYIQPEQKRNEILQRLKEPLADLSCSRTKFTWGIQVPNDPKHVMYVWMDALINYYSSCFIDEGKKKYWPANVHIIGKDITWFHTVIFPTILLSANIPLSKSVFSHGFVLAADGKKMSKSLGNVINPLEIIDKYGADAFRYHVIKETKRGCDTRFDVDNLVDMCNSDLADTIGNLVQRTLSLCQLCNESKIPAFYPEYEIHLPIDILHFINRVEYHMKTFCVQKCCEKSVQVCKDLNKFLTDMAPWKYKDDLKNKKLHIIRIMLEAIYFIAHYLDIFIPSLSHKIFEKLNTPKKVIADLSPWLNNLTEGVIINNDNILFKKYEVETAKIKLQKVIIRVCKIVNIINTESSQNTTICEIEVDNDKITAVLYLPYNNNNNKLVNLLTLAILNIKPLTINNITVNAIIPHVRKEIFTFPIEERIPTGTLIQGKNYKTLVKQRDNLTKKEVVSLDLSIINNKCFFEKNIPLVFASHEDKQVYHSTQDNGSLTFF