wanglab/gogpt-training-data huggingface dataset:
Protein: Gap junction beta-3 protein (Connexin-31) (Cx31) (P28231)
Organism: Mus musculus (Mouse)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Interaction partners:
- Gap junction beta-2 protein
- Gap junction beta-4 protein
- Gap junction beta-6 protein
- Potassium voltage-gated channel subfamily KQT member 4
- Gap junction alpha-1 protein
Sequence:
MDWKKLQDLLSGVNQYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTRQPGCTNVCYDNFFPISNIRLWALQLIFVTCPSMLVILHVAYREERERKHRQKHGEQCAKLYSHPGKKHGGLWWTYLFSLIFKLIIELVFLYVLHTLWHGFTMPRLVQCASIVPCPNTVDCYIARPTEKKVFTYFMVGASAVCIILTICEICYLIFHRIMRGISKGKSTKSISSPKSSSRASTCRCHHKLLESGDPEADPASEKLQASAPSLTPI
Protein: Probable transcription factor FL (RFL) (Protein ABERRANT PANICLE ORGANIZATION 2) (Q0JAI1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable transcription factor (By similarity). Together with APO1, involved in the temporal regulation of meristem size and identity during both vegetative and reproductive developments through interaction with APO1. Promotes flowering.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- Protein ABERRANT PANICLE ORGANIZATION 1
Sequence:
MDPNDAFSAAHPFRWDLGPPAPAPVPPPPPPPPPPPPANVPRELEELVAGYGVRMSTVARISELGFTASTLLAMTERELDDMMAALAGLFRWDLLLGERFGLRAALRAERGRLMSLGGRHHGHQSGSTVDGASQEVLSDEHDMAGSGGMGDDDNGRRMVTGKKQAKKGSAARKGKKARRKKVDDLRLDMQEDEMDCCDEDGGGGSESTESSAGGGGGERQREHPFVVTEPGEVARAKKNGLDYLFHLYEQCRLFLLQVQSMAKLHGHKSPTKVTNQVFRYAKKVGASYINKPKMRHYVHCYALHCLDEEASDALRRAYKARGENVGAWRQACYAPLVDISARHGFDIDAVFAAHPRLAIWYVPTRLRQLCHQARSSHAAAAAALPPPLF
Protein: Rho-related protein racC (EhRacC) (EC 3.6.5.2) (Q24816)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P63000}; Lipid-anchor {ECO:0000250|UniProtKB:P63000}; Cytoplasmic side {ECO:0000250|UniProtKB:P63000}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P63000}. Cytoplasm {ECO:0000250|UniProtKB:P63000}.
Interaction partners:
Sequence:
MSEKPTSIKLVVVGDGAVGKTCLLISYSIRKFPEDYIPTVFDNYVVSLTAGTRQIQLALWDTAGQEEYDQLRPLSYSSASIFLICFSVTSSVSYDNVITKWHPEVIHFAPKVPIILVGTKLDTRNDPAIVKRLTEQGMTVINTAKGEELKNRIKAVKYIECSAKTSENLKTVFDEAVKTVLMNKPQQRSKCALL
Protein: Gp150, isoform E (A0A0B4LGB0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSRQSTCRLVLLLAFTLALIHASHSNTVGPKIHFIHDDLTENELNSGEEVSPTESLPKISTPKVKDLPVETTTRSPTKKTTSSGTEKSLSEEAWNDLMEAAKHSQALADDPHFNKMLNTTVAAGEKNSTDTDDSEYYDYDDDYNYFDEETVTISPSPKKAKSNPKLQPIVDATITKSKTKESANDIDSDSQYDYDEGLDDDDDEDDAADDLLTDDEQVVFSEDVPCPRFCQCARNVNSYLVATCSRLDMGIQKFGSDITDLVVTNVGPKYPILMGPNFFQNLGLKNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDVGLAIINPDTFVGNKKLRMLTISGNDLSVMSSIHYLLKSSSIEELDFSRNNLMELNPKAFSHLSNVVYINLSQNSLKKLPEKAFEKVTLLEELDLSYNSLTELPRDIFNGTTLSILHLKYNTFNGDLHFGTKDLQQLDLSFNSIVQVHHSMFDKMPGLTNLNLKGNGIKKIQPDSFLTLKNLRHIDLSINDLDQISGMLFFKNSELDVIRLNDNPRLSQLPTDGFLSYSGEFTVYYLDISNCAIGPLGHKAFSTMPHLTTLKLAWNNINHLPREIFTGLHKLIDLDLSNNLITRMDDLIFMDNGELTKLSLAGNPISRLSVRLFLPLHQLRCLDVNDCELTTLLSDRDLGAGYKIFDSLRSFNASGNLIKKISSEDVKSFKNLRSLDITNNPLKCTPDFQEFISYVTLQMQMTPKRLPVLANLEDDATIVQLETLAQAGWSSLAHEVCKHAEGSDLLDEKKADSAEAKLEKRLKESVKKLNEDEAKLLSVLDKSVLDKSRLSSMQKIMKGSVNTETAKPEEDADEENLNNGGEDKEDDSSDYDSEEDDDDDDEDDDDDNNDDDRFEEAKKNAKAKADANKAFDTFVNKELKPVLKTDGIQAEEVDMSQETRDKFLLEKLGFDSESEESDEYTEKMIFHGELSYDLVVPLIVVSFCLLMIVLSIARVIYVVLRKRGERYRMALLASKNSFVYQKLSEDIVKPTSKEQKEPKHLKQPKVHRYAPINQV
Protein: Putative F-box/kelch-repeat protein At1g20940 (Q9SYP3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable component of an E3 ubiquitin ligase complex.
Interaction partners:
- Homeobox-leucine zipper protein-like protein
- F5M15.19
- At1g80245 component)
- 2-oxoglutarate
- 2-oxoglutarate
- Small ribosomal subunit protein eS27w
- C2H2-like zinc finger protein
- Zinc finger protein ZAT4
- B3 domain-containing protein REM17
- Cytochrome P450 705A12
Sequence:
MNNLPRNSQFDSSSIINDLPLDLLDEILFRLEPKSMAMMRCTNNSIKSYLSDPRFGPEYPSWVRPSLFNLGSYGATYVCCHPLVSSCDYMSPGNGVELFDGSADCYIFGSCSGLLLLYIGCLFVANPLTKRFRILDHSGSKLIPMIVNGGLKGLSGISYPGGNVACTERAMCVGFAVNRNLTTKRFKIVGILEMENVYGFEINEGDSWRLSETSITTSSKSDLTTRMKPVYLDNTLHWLRNDGSIMSFNPETEQACLIPSIFHREPDTKLLFAESVKINRLTLISGTIETISVYTLVENHKWTLTRRIKNISIEEETLVYWNIAMYDGKCLVVRVKKMGLEPLASVLHVYDMEANSWGVLVSTLAWPNCVRDFYKLTPSLFFVEEDEQQKVLVASNDRRISYINSIMGLIDTTK
Protein: Cadherin-1 (E-cadherin) (Q90Z37)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, adherens junction {ECO:0000269|PubMed:10456847, ECO:0000269|PubMed:19101534, ECO:0000269|PubMed:27760340}. Cell membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. Endosome {ECO:0000250|UniProtKB:P12830}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:P12830}. Cytoplasm {ECO:0000269|PubMed:28842668}. Cell junction {ECO:0000269|PubMed:10456847, ECO:0000269|PubMed:28842668, ECO:0000269|PubMed:29376824}.
Interaction partners:
Sequence:
MACVTTVGLGVIFFLFRVFSSGYTHMSICTPGFELEEFVFKVHRNHLHSGKRLGKVTFNNCDGRTRTLFQSIDKRFEINTDGTVTLKRQVTLHEGHKVFSVHAWDSSGMKHTASVRVERVPAQVESSSDVDLTKNKRVKRGWIIPPISVSENSKGPFPMRLVQIKSDYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLLDREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQVGVEVAKLPVTDGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRIGNDPSDWLNITGSGQIQVKNALDRESSNVKDGKYKALILALDNDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSITDKDLPPFAGPFKVEPQGDTSKNWSVFFNETGHFLNIKPQSQLEQGEYKVVLRVADREGESQENIIQASVCDCKGEAFQCTDKQVAGIPLFGVLGVLGGILLLLLLALLLLMFLRRKSNSKKEPLLPEDDVRDNIYYYDEEGGGEDDQDFDLSVLHRGLDNRPEVFRNDVAPTFMPAPQYRPRPANPEEIGTFIDDNLKAADNDPTAPPYDSLLVFDYEGGGSDAGSLSSLNTSSSGNDQDYDFLNEWGPRFKKLADMYGGGED
Protein: DAN related protein (Q76C29)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|PIRNR:PIRNR027807}.
Interaction partners:
Sequence:
MTFQVGFFVLLSVTTIGAFPRNAFQREFHRHVAKDFESSGNGPDEPVRGSVRIVKLNPHFLRRAAVSHVPFRNSPSRGAFPAFLALGRPGPAILTHSKPAPQVSSSADRRKQGLEMWKKVVHKSERKKEAVALRINPKDMNKQSCAAVPFTQRITEEGCETVTVHNNLCYGQCSSMFVPSSGGSHGQQKAQCMRCGPSRARSVLLHLRRGSEVRERRVLIVEECKCETSSEEAKVQNTDMFNL
Protein: Phospho-furanose lactonase (EC 3.1.1.104) (EC 3.1.1.25) (A5IZ80)
Organism: Mycoplasmopsis agalactiae (strain NCTC 10123 / CIP 59.7 / PG2) (Mycoplasma agalactiae)
Function: Catalyzes the hydrolysis of D-xylono-1,4-lactone-5-phosphate and L-arabino-1,4-lactone-5-phosphate. Also able to hydrolyze carboxy 1,4-lactones.
Interaction partners:
- Pentitol phosphotransferase enzyme II, Bcomponent
- Ascorbate-specific PTS system EIIC component
Sequence:
MAKDKFVRTVLGDVPAESIGITDCHDHLIKNGGPEMHEHPDFLMIDVEAAKKEVQEYVDHGGKTIVTMDPPNVGRDVYRMLEIAEAFKGKANIVMSTGFHKAAFYDKYSSWLACVPTDDIVKMMVAEVEEGMDEYNYNGPVVKRSKAKAGIIKAGTGYAAIDRLELKALEVAARTSITTGCPILVHTQLGTMALEVAQHLIGFGANPRKIQLSHLNKNPDRYYYEKIIKETGVTICFDGPDRVKYYPDSLLADHIKYLVDKGLQKHITLSLDAGRILYQRNYGLTKGKETFGLSYLFERFIPLLKQVGVSQEAIDDILINNPREILAFDEPRVYDASKVSSEVVQLKKDLKLL
Protein: Protein SENSITIVITY TO RED LIGHT REDUCED 1 (Q8GWZ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable regulator involved in a circadian clock input pathway, which is required for normal oscillator function. Regulates the expression of clock-regulated genes such as CCA1 and TOC1. Involved in both the phytochrome B (PHYB) and PHYB-independent signaling pathways.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12533513}. Nucleus {ECO:0000269|PubMed:12533513}.
Interaction partners:
- Agamous-like MADS-box protein AGL63
- AP2/ERF and B3 domain-containing transcription repressor TEM1
- Cyclic dof factor 1
- Protein SUPPRESSOR OF FRI 4
- Phytochrome B
- Chlorophyll a-b binding protein
- Gibberellin-regulated protein 8
- 2-oxoglutarate
- Protein VERNALIZATION INSENSITIVE 3
- Protein PAF1 homolog
Sequence:
METTVKNSSSDGEWKVVLPSKGRQGRRRKPKPKGQAEEEEQPWKSDDLEIDPQRQARLKQKMEISLKKIESSSFYTAFLEQLKSPEVSNQIRLVLGSETQLQMVMYGIGSIESYESPRFQLSIAILMKREFDWVGDNIEVFDPVLSATESSYLESLGCSVLSVNEQARREALKPTLFFMPHCEANLYSNLLQANWRMDRLSKIALFGNSFQMYEEQVSFDAEVICATKRIIAAQRVTSEFAIETESDDYFAAFHDSSWHFFSSGIDSELPLFVSD
Protein: Major facilitator superfamily multidrug transporter NAG4 (N-acetylglucosamine utilization protein 4) (Transmembrane protein 2) (Q59RG0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: MFS transporter involved in N-acetylglucosamine (GlcNAc) uptake. Confers resistance to cycloheximide, 4-nitroquinoline-N-oxide, and 1,10-phenanthroline, and contributes to virulence.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSHATDSTLDNASVDSEKVRDFGDDLQNHPVQPTRSILSKIRSRDDDARSLVSNNKGVERIISDLQEGAGQLGPLEQPYDIKKIETHPDPHTDYNEADPWKYPIDSESGLRLVEWVDGDKHNPKNISKAKKWLYTLVLGAVCFVVALGSAIVTGDMERPAEYFGVSEEVIILASVTVFVIGFGVGPLVFAPMSEEVGRKPIYVVTLFIAVVFIVPCGAAKNIATLIVCRLIDGIAFSAPMTLIGGSLADIWEGPERGTAMAIFSAAPFLGPVCGPIFGGLLCDHAPTWRWIYWTFLIVAGVFYAIFIAIVPETHHGILLKKRAKKLRKETGDSRYRSFNELQIRSFGEVAKTSLLRPFVLLSELIVFLMTIYMAICYGLLYMFFFAYPVVYQQGKGWSASLTGVMFIPIGVGVIIATIAAPFFNKDYNRRAQVYRDRGELPPPELRLIPMMIACWFVPVGLFAFAWSSYTWVSWAGPCFSGLAAGFGFCCLYNPANNYIVDSYQHYAASALAAKTFVRSIWGACVPLFTIQMYHRLGDQWATSLMAFISLACCAIPYLFFFFGARVRTFSRYAYTPETNTK
Protein: Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin) (Q8BYI9)
Organism: Mus musculus (Mouse)
Function: Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. Theses interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediates inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- Aggrecan core protein
- Integrin alpha-9
- Integrin alpha-8
- Integrin alpha-V
- Integrin beta-1
- Integrin beta-6
- Integrin beta-3
- Syndecan-4
- Syndecan-1
- Brevican core protein
Sequence:
MGIDGETVVLKNMLIGVNLILLGSMLKPSECRLEVTTERAQRQTVEEEGGASSYNTSSKEQPMVFNHVYNINVPLESLCSSGLEASAEQDMSAEDDTLAEYIGQTSDHESQVTFTHKINLPKKACPCASSSQVLQELLSRIEMLEREVSLLRDQCNTNCCQESAATGQLDYVPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTIMELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWTPPRAKVDFILLKYGLVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESEASSTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDKEEDMLEVLLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKNITISNVTKDSLTVSWSSPVAPFDYYRVSYRPTQVGRLDSSVVPNTVTEFAITRLYPATEYEISLNSVRGREESERICTLVHTAMDSPMDLIATNITPTEALLQWKAPMGEVENYVIVLTHFAIAGETILVDGVSEEFQLVDLLPSTHYTVTMYATSGPLMSGTIATNFSTLLDPPDNLTASEVTRQSALISWQPPRAAIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTVFTTGGRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNIHRITAQGRYELRVDMRDGQEAVFAYYDKFAVEDSRSLYKIRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRPYIHRLTAGRKRRALKF
Protein: Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese) (P00586)
Organism: Bos taurus (Bovine)
Function: Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (By similarity). Formation of iron-sulfur complexes and cyanide detoxification. Binds molecular oxygen and sulfur.
Subcellular location: Mitochondrion matrix.
Interaction partners:
- Cystathionine gamma-lyase
- Sulfite oxidase, mitochondrial
- Cysteine desulfurase
- Persulfide dioxygenase ETHE1, mitochondrial
- Aspartate aminotransferase, cytoplasmic
- Putative aspartate aminotransferase, cytoplasmic 2
- Adenylyltransferase and sulfurtransferase MOCS3
- Aspartate aminotransferase, mitochondrial
- Sulfurtransferase
- Cystathionine gamma-lyase
Sequence:
MVHQVLYRALVSTKWLAESVRAGKVGPGLRVLDASWYSPGTREARKEYLERHVPGASFFDIEECRDKASPYEVMLPSEAGFADYVGSLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAIFKATLNRSLLKTYEQVLENLESKRFQLVDSRAQGRYLGTQPEPDAVGLDSGHIRGSVNMPFMNFLTEDGFEKSPEELRAMFEAKKVDLTKPLIATCRKGVTACHIALAAYLCGKPDVAIYDGSWFEWFHRAPPETWVSQGKGGKA
Protein: Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Q5XHX6)
Organism: Rattus norvegicus (Rat)
Function: Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Thioredoxin-interacting protein
Sequence:
MFKKNQKLSKDKGLEVNSVQAGAPEESDVKLNNGGKANERGSNEFLDTAQSKEKVIASVVGNMLHMSTEESEPPQQVSSTSMFSENTIYPKHEGSPKSSTKNTQLKQEDISKTSSYSKQTNSSNIPKSLAITTYPKQGSTLKPAANGTHDREAEKPKSSEDLIQSKKGDIFKPSEDSIQSKKGDMPKSSEDPIQSKKDDTAKSLEDTIQSKNGDMPKSSEDPIQSKKDDTARSLEDSIQSKKGDMPKSSDTIQSKESETPKFLQDTIQSKGGKINKQVKDSMKSKESKIRKPLKDSIQSKENKIPKSSQDSAQPKEGKIHKPLKDSLPSKEGDISKPSEDTIQAKEEITVSPEDTIQAKEEITMSPEDTIQAKEEITVSPEDTIQAKEEITVSPEDTMQSKEEITVSPEDTVQSQEGDIKSSEDVQPSENEIFPFEAEIETLEEGMVRVIKDKEEFEEVLKDAGEKLVAVDFSAPWCGPCRKMRPHFHSLSLKHEDVIFLEVDTEDCEQLVQDCEVFHLPTFQFYKNEEKVGEFSGALVEKLEKSIAELK
Protein: Tubulin tyrosine ligase-like 4A, isoform E (Tubulin tyrosine ligase-like 4A, isoform F) (Q9VKL9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSKFQKAGASRRDSREVDGTVIIGRRDNSEDRTWQGQKYEKHVLKEKLPSNDLKADYLDNGWGGDPGSEDDYRDIKDSYDPVVVIDNGLEQVGVHRRYCRMTENTVLDGSGDTLINNNNNELKIMRKSTDQPMPRLPMTPKRAKGGTVSTKKPMPTVHRVLLYSTQSPRLGRKQQFSTQRLSVKQQSSKVLGAGDERQTVLLLEPEHKQEDHRSAIDFDRNDDFDEDDDLDNLSNFDESDTASVLSDTEDGYRAHAFKLTHSVDRFSSPQSTPSFLSSQSSEDDLKNPDSLLVPSLFPYVPPYLSFSSNTKRGPRVPPDLHRVLKWRITNIMPKVVRLILANSGMRMLKKTNDWMGVWGKHLKSPCFKAIRSYQKINHLPGSFRIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWPKYAQRNTKWIIKPPASARGAGIRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLARFASVKYSAKTDTLNDRCMHLTNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYLANRGVRTDCLWEALRSLVLRTILAGENGINSMIRANVESKYSCFELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKELAAEFSFPPGTQMCYDKRLYINYLSREEKIKHNTFTRKSMEDRNEYVDAILNNLTPDDVRCLIIAEDELARCAPLERIFPTDQTHKYLKYNDTPRYYNRLLDAWESRYANNRTEGIALLRDYCQNKYHLQVPTPPAKKDSNDEETTPATPNTVKEEIES
Protein: Antares, isoform A (IP09869p) (Q4V3Y4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKMWYLYLFLLPLTASLIPEDDPHCKPNLCMNSEIHAVGEQCGKNNLFLNVNGALKTGILSRINMLRNYVASGVGNYSVAARMPTMGWDFELQRLADRQVRQCDETGKFCANTDKYHYVATTEIRSKMGRTKSLKSAILDKLLPELFLDVMGCMMNSQKLVPVREGTCVGHYMPLIQDHGSRMGCGLRVKGRDEKESNIILLCHFSRASVNNLVPYEEGQIPAGKCATGPSQMYQFLCSEDEYVDANSMVVESNMPSSDQIQVDI
Protein: Jak pathway signal transduction adaptor molecule (LD02639p) (Signal transducing adaptor molecule) (Signal transducting adaptor protein) (Q9XTL2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endosome {ECO:0000256|ARBA:ARBA00004177}.
Interaction partners:
- Hepatocyte growth factor-regulated tyrosine kinase substrate
- Tumor suppressor protein 101
- FI19924p1
- Ubiquitin carboxyl-terminal hydrolase
- Myopic
- Vacuolar protein sorting-associated protein 28 homolog
- GH14561p
- Vacuolar protein-sorting-associated protein 36
- Vacuolar protein sorting-associated protein VTA1 homolog
- Multivesicular body subunit 12A
Sequence:
MGIFGQSSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRMGHTDPHVVMQAITLLDALSNNCGKPLHLEVASRDFETEFRRLLAKAQPKVSLKMRQVLKNWAENDYKNDRELDLIPALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTEAAAAAAAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAELERVDRKHAQLTQLSSDLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGFPPAQNYPGMHSMPYGPVPNPPTSAPSQAPGAPGGYLGQPQGQVPLPYQNGHAAQMNSLPAHLTQPTGTAPMPQPIYTQPTPVTTQQQQQPLPQHPQQPPQQQGQQPPQHPQNSYHIDPQSQYAQVPPAVTQIQQPQQPPAPHAYMSPQHQQAPPPQGYQPGPNLYGPNGSPAVVNPQSYMSPQQQQQQHPPPHDQFSQLHQQMAAMSMAGGPPVGAPGYHMQNDAVKNNIPIYQQQR
Protein: Glutathione peroxidase (W8W0V5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MAGKIKKFYDFSAKLLSGDLLHFSSLKDKVVLIENVASLUGTTTRDYTQMNELHSQYSEKGLVVLGVPCNQFGHQENCKNDEILRSLKYIRPGNGFEPKFPLFEKMDVNGKDAHPLFVYLKDKLPFPSDDSMALMSDPKFIMWSPVCRNDVSWNFEKFLVSPDGDPYKRYSRRFLTSDIEADIKELLNVK
Protein: Receptor tyrosine kinase (Q9GP68)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MESTTIVFVTLLTIITQRKHCAAVDVYFPTTSVKFNLPINEESESIFSKIPLAQFQVLRMEDNRLASDYLYSLEQNPLLRINSSSGEIYMRTDYRSPNSSATFLVTAFPRDQPDHELLNVSHLSLEVTPQPLEEYCSELEHICFWSSAQYTIAESHGPYRRKDFFEPVLIGALNSRAAKYLCPHVSLEYSLNAGSSHFVLKQNRLYTRQTLDHDELNGLNAKAGQLQARITCTVKLSSRDQRKFSRILDIKLLDRNDNGPKLQESSSKFDFYLEQPYFQADEEAGKKVIYVDKDTLEANAHLVYAVHNDSHGLFRPDCHAYEADHTGRPHTIVSCQLRFSRNGVFRETPYCVSLEARDLTIVSRVDAMSATANVCYHINLSKLHESEQELPQALPLRARLHRIFESEEFNGDSAGRSL
Protein: Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (Serine/threonine-protein kinase SAK) (J3KR84)
Organism: Homo sapiens (Human)
Subcellular location: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}.
Interaction partners:
Sequence:
MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEESSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
Protein: Sec-independent protein translocase protein TATA, chloroplastic (Protein THYLAKOID ASSEMBLY 4) (Protein TWIN-ARGININE TRANSLOCATION A) (Q9XH46)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000305|PubMed:10402459, ECO:0000305|PubMed:14653819}; Single-pass membrane protein {ECO:0000305|PubMed:10402459, ECO:0000305|PubMed:14653819}. Note=The C-terminus is located in the stroma.
Interaction partners:
Sequence:
MEITLSISSSSVIPTRLPNSSCYSNLSFLSSNSNTSSLLLKKARIKTRTTKGFTCNAFFGLGVPELVVIAGVAALVFGPKKLPEVGRSIGQTVKSFQQAAKEFETELKKEPNPTEEISVASEQEKQEIKVSSTKDNV
Protein: RE45222p (Spatzle 6) (Q9W116)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Protein spaetzle 4
- Neurotrophin 1
- Protein spaetzle 3
- Protein spaetzle 5
Sequence:
MDYRLVLKILSFLLLAQLGFSQPQQQSPSDYGEEQPPEGYYAFVESPNAVPPKVRPPPYTFVNAECKDVAAGKKSAVSVHNICGDLNKGQIPKNPLGQNVLGEPYPFELIRNQTLKFLSKTLPVLKADDTLPKVTQIIRDEPVEQLDSNNIDRPYPAGGSTRVRRSLPEGVESNEYSYFDPALDEEEQHKQRDRNNQQRRAAEERKPRKFCDGGGVFCTLYRAIQGDTGGAAPATPTAERREEVGPIRYEGPPTPCPAKVEYATPVFAKNYQGAWRYVVQIPYEGYFTQTVEVTRCIQARCHYLDGGCLSSPRWVSLLVAEIFYPNAEDTVPTSSTTTQAPSVQDFQAYQQYLQKRAGVATASDGTSSGAAGPAAQVDAHCDGHDELGCFQVRLYYDWFLIPGSCKCWRPDYFAKYVRRKSVAEL
Protein: Membrane-bound lytic murein transglycosylase C (EC 4.2.2.n1) (Murein lyase C) (P0C066)
Organism: Escherichia coli (strain K12)
Function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
Subcellular location: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Membrane-bound lytic murein transglycosylase D
- Membrane-bound lytic murein transglycosylase F
- Membrane-bound lytic murein transglycosylase B
- Membrane-bound lytic murein transglycosylase A
- Soluble lytic murein transglycosylase
- Probable Fe
- Endolytic peptidoglycan transglycosylase RlpA
- Endolytic murein transglycosylase
- Anhydromuropeptide permease
Sequence:
MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
Protein: Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Q8R2Y8)
Organism: Mus musculus (Mouse)
Function: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9Y3E5}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLSKFLTMEYLVHPGTLSLAAGVACGMCLGWGLRSHLGMFPQNSTSEANRDTETGTEASILGESGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAPDEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY
Protein: Enoyl-CoA delta isomerase 2, peroxisomal (EC 5.3.3.8) (Delta(3),Delta(2)-enoyl CoA isomerase 2) (AtECI2) (Indole-3-butyric acid response 10) (O23299)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Essential for the beta oxidation of unsaturated fatty acids. Involved with IBR1 and IBR3 in the peroxisomal beta-oxidation of indole-3-butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin.
Subcellular location: Peroxisome {ECO:0000269|PubMed:17951448, ECO:0000269|PubMed:18657232}.
Interaction partners:
- Enoyl-CoA delta isomerase 3
- Short-chain dehydrogenase/reductase SDRA
- Enoyl-CoA hydratase 2, peroxisomal
- Enoyl-CoA delta isomerase 1, peroxisomal
- Probable acyl-CoA dehydrogenase IBR3
- 3-ketoacyl-CoA thiolase 2, peroxisomal
- ABC transporter G family member 36
- F5M15.19
- Dehydrogenase-like protein
- Probable enoyl-CoA hydratase 1, peroxisomal
Sequence:
MCTLEKRGDLFLLTLTGDGEHRFHPDTIATILSLLEQAKSQSTRGSILITTANGKFFSNGFDLAWAQTAGSKTGAANRLHQMVESFKPVVAALLDLPMPTIAALNGHAAAAGLILALSHDYVFMRKDRGVLYMSEVDIGLSMPDYFSALVRAKIGTSAARRELLLSGKKIRGEEAVGLGIVDSAAYDSEEGVVVASVRLGEKLAAKKWSGEVYASIRKSLYPELCGILGLETRVFATPKL