wanglab/gogpt-training-data huggingface dataset:
Protein: Probable transporter SEO1 (P39709)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known; suppressor of sulfoxide ethionine resistance.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Clathrin adapter accessory protein LAA2
- Outer spore wall protein LDS1
- Putative uncharacterized transporter YOL163W
Sequence:
MYSIVKEIIVDPYKRLKWGFIPVKRQVEDLPDDLNSTEIVTISNSIQSHETAENFITTTSEKDQLHFETSSYSEHKDNVNVTRSYEYRDEADRPWWRFFDEQEYRINEKERSHNKWYSWFKQGTSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVGNIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEGWRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVFDIKLWKTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSLKRYSIPKLNQLSMITPGLGMVYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWFAFMLQCFGWAMAPVLYSWQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKGFTFTACSAFCLSIWTFVVLYFYKRDERNNAKKNGIVLYNSKHGVEKPTSKDVETLSVSDEK
Protein: COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) (P61202)
Organism: Mus musculus (Mouse)
Function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10087198}. Nucleus {ECO:0000269|PubMed:10087198}.
Interaction partners:
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 8
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 7a
- COP9 signalosome complex subunit 7b
- E3 ubiquitin-protein ligase RBX1
- Cullin-2
Sequence:
MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA
Protein: Zc3h12a-like Ribonuclease NYN domain-containing protein (Q9NA28)
Organism: Caenorhabditis elegans
Interaction partners:
- RNase NYN domain-containing protein
- MUTator
- MUTator
- RNA helicase
- Non-specific serine/threonine protein kinase
- Hypersensitive to pore-forming toxin protein 40
Sequence:
MDPPRPPGTRLVLNTAGHLISVPESMFDQPSTSFWGNGPTSVPVDDECDREEPATHQESSESDSDYSDGEEATPEQWKELDKELDKVVALLKEYEAAKVTETDPVKRYRNLCQLSTTLKTISVKDGGWKILHKEHTEKEKLALDRANFDILKFVYARHEKILDDGKSFITRFELIDAKIADLISRFIQMHGEHSFRAGSLSVAVGFDEFPPELTWRTTPTNKIIMLRPVVIDGVAVLNATMDDDTWMPFMEITKNCRDWIYEPELNLPVKPLTDIILLFLIRGHKTTVYLPKYYQEFLSDCGVSKVDDLVAFQKLIDLGFIKFLEITNPFNFKWFNVVADLADRCGAVFVSSEDYRQRKMKINYSKPSGRIITPCFLNAEDRLLVLDPTIRYRKPGEKTYTVISSDRILQFDEPDDERIKLSEQLYLDQQIKLICSLCQLYPVKMINKVAIKQLLELVVFAGADFEMPGMSIEDYEKLYDRYGREAFFN
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (Q8T0I2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRPYIHKDCKSEVAIYNLSSVICHHGTVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQSCQAYVLFYHKHNPQMKLVRDEAMTLSTSHPLCDSDIQFYITREWLSRLATFSEPGPINNQEMLCPHGGILHSKADVISQIAVPISQPLWDYLYRTFGGGPAVNIIFECEICKRAAETLSRRQQYELNEFTKYNGLQNEFDSTAIYAIAMPWLRSWQQFSRGKTHKDPGPITNEGIAAPTENGSATVSCVRLGSDYAQLNARLWRFLHNIYGGGPEIILRQALSDEDDAEEIEIIDQDDECDDDEDQDLEGEGEDEEIAAASYQHNHSDTESNLGIRNTPSPSPSTSPSPSLTGTRQPMETESDLRPSSSKSKRSRSKMKVSALRLNMRNRGKRNRSAFKQYAEMFGAKGNYNAHSNAEPVVSEKDEKDKDNDRTVAFPSEYSLPISIPFQSDNFQVNGVHEKSRDKGKLRNSSKSGSTAATKENVTLQKFVTLREANGPSDETDI
Protein: Uncharacterized protein (Q389D7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Ribosomal protein L30 ferredoxin-like fold domain-containing protein
- Large ribosomal subunit protein bL21m
Sequence:
MVLPRKLVGQCCLLLQKKQTAASYMANAGKVGSEEKWAQAAMEYLHEKRHCNDSRKRQHDVDNERRMAFAFDRYCSVNEKIFTERLSRLSDRMTEALETIKQLGMDHALEEALMLSSEQPPLNFRRPTLTPPVAGYEPGFGLDVPQLRSRQAEYPPVGRPTDAMEFGEEKDPSFPLVESFRVEDLTTQCLNELEERHGEIREAAPTTGVEGEAWEAYVALQKKALARQQLIFELCNDGELRERYDSDVAFRQRVWEERGMLPLEIERERLHEEPRHYAQEPAYHPFRKM
Protein: Orphan antitoxin ParD2 (Q9A9D4)
Organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus)
Function: Antitoxin component of a non-functional type II toxin-antitoxin (TA system). Does not neutralize the effect of any of the RelE or ParE toxins.
Interaction partners:
- Toxin ParE1
- Toxin ParE3
- DNA topoisomerase 4 subunit B
- Antitoxin ParD1
- Antitoxin RelB3
Sequence:
MFWIFVMAKPASLSIELDSDLDRRLSEIAEGMDQPKTAIIERALRDFVELRDWQDAAIDEGLRAAEEGRVFDHDKVGEWIDSWGTPNERPMPSRD
Protein: Endoplasmic reticulum transmembrane protein (B9EQV3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU367026}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU367026}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSLVWTLIAGFLYAEIALVLLLVLPVLTPYRWNRFFKSKFLSMLGQQAHIYFLLIMGILVIFLLEAIREMRKYSGLQQSNEVHLNVEMQHSMKLFRAQRNFYISGFAIFLALVIRRLVNLICTQANLMAQSEASFKQAQSATAAARSLLENKNTEKAKEAGEDTTLIELSRLRRRVQGLTARVS
Protein: Uncharacterized transporter YNL095C (P53932)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Uncharacterized protein YNL162W-A
- Putative uncharacterized protein YNL089C
- Uncharacterized membrane protein YNL019C
- Carnosine N-methyltransferase
- Mannose 6-phosphate receptor-like protein 1
Sequence:
MVHITLGQAIWVSVKPIIKIYLIIGVGFLMAKMGILTVEATRIISDIVLTVLLPSLSFNKIVANIEDKDIKSVGIICLSALLIFGSGFFFAYVVRLFLPVPKQWYGGILAGGMFPNISDLPIAYLQSMDQGLVFSEEEGNKGVANVIIFLTMFLICIFNLGGFRLIESDFEYNDDESAVRVSETTKTQPAVSANTTNTDTSERFFSNEQQLFNNKYTARDSLTEAIGTKGENADVPPISRRSTNSIAPLSLPDTSSNSKITKPVQVKARNTIACTQSEESQATRGSNPLDSQSSASTIHSYNTSESYESSIDTMRARRTASQPRAYNTTTLLEENCLDEKCPKNMSMAALEPIRSIDMRALPSQNIHHLIREYSNVDQYGHQRRNSSLRGADMNDVHSISSNSTLQTIKTANLTRILTSDATVSKKDIETSGESLPQWMRKFSLTPLLVFFLKNCLRPCSMAVIIALTVAFIPWVKALFVTTANTPHISQAPDNAPPLSFFMDFTGYVGAACVPFGLILLGATLGRLKIGNLYPGFWKAAVTLVILRQCVMPIFGVLWCDRLVKAGWVNWQDDRMLLFVIAISWNLPTMTTLIYFTASFTPPETTAPIQMECVSFFLMLQYPLMVVSLPFLVSYFLKVQMNL
Protein: FRAS1-related extracellular matrix protein 3 (P0C091)
Organism: Homo sapiens (Human)
Function: Extracellular matrix protein which may play a role in cell adhesion.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Glycophorin-E
Sequence:
MAGASRHPTGTPRQLLVALACLLLSRPALQGRASSLGTEPDPALYLPARGALDGTRPDGPSVLIANPGLRVPLGRSLWLDPLRDLVIGVQPGDRCEVTVLDALPRLKGALSPRRFPCTFGPRQVQYTHFGSHSPGRARVLLQLRYDAPTHTLVLPFTLAVDLVFSQLELVTRNRPLVVEKLRSWSRAIDRRVLDFASLKSGATATRRCRLTPLPHEDGPLPKYGRLVDAVGAPLPRGKGVDCEAFLRAGVRYQHTATSSPNRDYVPMMVELLGPEGQDAGSAGVLVREHFQLLVRIRGGAENTPPRPSFMATMMMEVDPLVLTALTPDALAAEDVESDPGDLVFNILNAPTHPPGHPGQQGYVVSTDDPLGLPVSFFTQQELRELKIAYQPPAENSHGERLFQLELEVVDGDGAASDPFAFMVTVKSMNTLVPVASHNRGLVLFEGQSRPLSSTHSIPISDKDNLEEVKMAAVRGLRHGQLVVFGAPAGCKYFTPADLAAGRVVYQHDGSNTYSDNIIFRMEDGHHQVDFLFPLTILPVDDEPPMVNTNTGLSLTEGQVVQISPFVLSATDIDSEDSTIHFVLENQPLKGNEEEPQWELAPGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDIMEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLSKQHIFTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLTLPTDTDGNHQVRAGEIVLTDSPDTLIMHFTQAQVNQHKVAYQPPQKLGIAPRVVQFTYQVEDAAGNSVPGTFTLFLQPVDNQPPEVTNRGFAILEGGSFNLSSNELHVTDPDTDIDQIVFILVRGPQHGHLQYFKRCMVPGESFMQADVINGSVSYQHGRDQTTTSDTFHLEVSDGVHHIPITIPISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVIHGKRKDVGDLMLSFIVKDSPKLGTILVNGLPTERFTQEDLINGRVAYAHTAGEVGFQKQHDAFSLILSKDSYQWVVGNSIIEKVQVQVTVLPVDNVGPKVFVGESFIVYEGEKNSLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRDIQVRHINYVQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEFKVLEGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRIIQQLATGSQPIHSFTLKEIQEASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKVPIVVTLVDDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGLLQRLRKPRGEVRNNLTLGMNFTQDEINRGLICYIHTGQEGIVDIIKFDVTDGVNTLTDHYFYVTIGNLDSVFPEVISKRITLIEGARVTLTNNLLTNSDINSSDEHHFSITRAPSLGHLESSDYAGEPIASFTQLQLASNKISYVHTSNDEKKMDSFEFQVIGELYPVFRTFRIFITDVDNKKPILTIHRLTLQKEDSQLITLLELTVEDSDTPDDLILFTITQVPMHGKILYNGSRPVTTFTKQDLNKNLISYKHDGSETTEDSFSLTVTDGTHTDFYVLPDTALATHKPQVMRVQIRSLDNRLPQITTNRGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISYVLNEGSNASKDIFYFSVEDNGGNKLTNQPFHLNWAWICLEKEYYIVDEDSTFLEVTLTRRGYLGETSFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVRIIPDNEYETSETFQIILSEPLMAVLEFPEMATVEIVDPGDESTVYIPEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTILADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDLSQPSSIAVRSRKSEQESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDDLGQPTLEGPEKFELLLQMPMGAVLGEPNKTTIFIEDTITDCKQSACSSFD
Protein: mRNA 3'-end-processing protein yth1 (Q9UTD1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Pre-mRNA polyadenylation factor fip1
- mRNA cleavage and polyadenylation specificity factor complex subunit pta1
- Cleavage factor two protein 2
- Poly
- Endoribonuclease ysh1
- mRNA 3'-end-processing protein rna14
- Polyadenylation factor subunit 2
- Protein cft1
- Uncharacterized RING finger protein P8B7.15c
- RNA polymerase II subunit A C-terminal domain phosphatase ssu72
Sequence:
MTDYIKDKAIAADFSSVQFRFDNYLKQNFNFGRSALLNSGNGRDSGSKMGSVVCKHWLRGLCKKGEQCDFLHEYNLKKMPPCHFYAERGWCSNGEECLYLHLDPSKQVGVCAWYNMGFCPLGPICRGKHVRKPRPCPKYLAGFCPLGPNCPDAHPKHSEPPHPPQKRKDW
Protein: Neuroligin 1, isoform D (Neuroligin 1, isoform E) (RE29404p) (Q9VIC7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Neurexin 1, isoform F
- receptor protein serine/threonine kinase
Sequence:
MKFRLAAFWLFLLTVGGNHKLLSHVSPMGVAAEKQPLHKGNELENAMKLREAPKQSRVIGDITTTIQPDSDPGRSIGHQALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTNSLESGEDHPQAPPETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLGGTILSYDGANDEELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQPILSDGRLIICQDIEVADAALLIPQHMHEPQHYEMLLQRQHSALTEPSDEILQQQYPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDINVTSRDDSDGLEVIPLTSAQQLELLRQRNYPKVLPTEQDLINSSYKRNSLPPQNFNAPLPPPRTISNTLGRRRRDSSNITTSPLQVARDCGGEDEDLKEPQITQNTLIVGPIVPKSPASSLKRVKRMPESSAMTALSGSFQSFEAVPPAHETTPPQGGERTECIYAIRPSPGSCSWAAPNGDLYAQPMKSSSRNSLIPRPTKPAESQSQATPAGPAGESLGSTGMATASRIPQLQRQASGKDLQARTATDNTANPLGCQPRTDSTISSGSSASYASTTDSSSSSSTGTVRTELQQFQPAPGRSITTNI
Protein: Probable polyamine oxidase 5 (AtPAO5) (EC 1.5.3.-) (Q9SU79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Flavoenzyme involved in polyamine back-conversion. Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives. Substrate preference is spermine > N(1)-acetylspermine > thermospermine > norspermine. Plays an important role in the regulation of polyamine intracellular concentration. Involved in xylem differentiation by controlling thermospermine homeostasis, and participating in the tightly controlled interplay between auxin and cytokinin that is necessary for proper xylem differentiation. Involved in the production of hydrogen peroxide in response to salt and cold stresses.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24550437, ECO:0000269|PubMed:24906355, ECO:0000305|PubMed:26973665}.
Interaction partners:
- Spermine synthase
- Spermidine synthase 1
- Spermidine synthase 2
- Amine oxidase [copper-containing] alpha 3, peroxisomal
- Amine oxidase [copper-containing] zeta, peroxisomal
- Amine oxidase [copper-containing] gamma 1
- Amine oxidase [copper-containing] gamma 2
- Amine oxidase [copper-containing] alpha 2, peroxisomal
- Amine oxidase
- Polyamine oxidase 1
Sequence:
MAKKARIVIIGAGMAGLTAANKLYTSSNNTFELSVVEGGSRIGGRINTSEFSSEKIEMGATWIHGIGGSPVYRIAKETGSLVSDEPWECMDSTIDKAKTFAEGGFEIEPSIVESISGLFTALMELAQGKEISQSDADLSRLAHIYETATRVCSKGSSTSVGSFLKSGFDAYWDSISNGGEEGVKGYGKWSRKSLEEAIFTMFSNTQRTYTSADELSTLDFAAESEYQMFPGEEITIAKGYLSVIHHLASVLPQGVIQLNRKVTKIEWQSNEVKLHFSDGSVVFADHVIVTVSLGVLKAGIETDAELFSPPLPDFKSDAIRRLGYGVVNKLFVEMSQRKFPSLQLVFDREDSEFRFVKIPWWMRRTATITPIHSNSKVLLSWFAGKEALELEKLTDEEIKDAVMTTISCLTGKEVKNDTAKPLTNGSLNDDDEAMKITKVLKSKWGSDPLFRGSYSYVAVGSSGDDLDAMAEPLPKINKKVGQVNGHDQAKVHELQVMFAGEATHRTHYSTTHGAYYSGLREANRLLKHYKCNF
Protein: histidine kinase (EC 2.7.13.3) (Q9A3H9)
Organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus)
Interaction partners:
- Sensory/regulatory protein RpfC
- histidine kinase
- histidine kinase
- Sensor protein FixL
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
Sequence:
MFARFFRDAPQPETARPVKAWPCQCGFGAVRLDTVSANQPRGLPAPPDPPAFLARMGDAGLAIAAHDWSEIPMGFPQAWPPALKVAAGMMLASPIPSFLAWGDEALLLHNDAARALLVARGLGARFDDVFPIPAGLPLLRRARAGESVVQECVGFTRDNGEAAWCNLMFSPVCGDEGQVLGVLVLCNDITARVRQERAHRADERRYQALFESMDEGFCVIEFFDGPHGPDSDYVHIMANAAYERHAGIFNVVGQTLREVVPEEADAWVARYGAVLRTGEPIRFEQELVATGRHLELSSFRIEPPELKQVAVLFQDVTARKRAEADLRGLNETLESRIAQALAERERTEEALRQAQKMEAVGQLTGGLAHDFNNLLAGISGSFEMIGARLAQGRAGEVERYLTAGQGAARRAAALTHRLLAFSRRQTLAPRPMVVNRLLPDFVELVRRTVGPSIKVENVAATGLWPTLVDANQLENALLNLCINARDAMPDGGKIMIETSNRWLDGPAAREHGLDPGQYVSVSVSDTGTGIDKATLERVFDPFFTTKPIGQGTGLGLSMVYGFARQSNGHVRIYSEVGHGTTVCLYLPRHLGEEEVETSTTAPYAPHVQADKTVLVVDDEPTVRMLVVDTLSELGYACLEAPDGAAGLRILQSGRQVDLLITDVGLPGGLNGRQVADGARALLPRLKVLFITGYAENAVLNHGHIEYGMEVLTKPFAVSDLTGRVDRMLGEA
Protein: Trichohyalin-plectin-homology domain-containing protein (Q387C9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVTTQPNQRRKQGRAHSLGMASEQREYEAIMAQIKNIMLLANEEPPQGEDEASIAKRIDLLQQALGALEQRAKDNQLMVEVMRTNLLNKRQERLVETAQQRQEKLSKKLEEREKFIHLLQEDRKYMLSQKHEVADSRMGLVQENAYNLFTTAHAKAEAERQRREKAVERIYEERARAVKEHRDRTQQREDQNREALLRQKKQEKLQRRQRELEIQEHDKYVAKRQYEADRKQQEAMREQWQPYLRNGASSANALQRCGSGMTAHEAARQNLMDELKEKEKQHQERYEEEQITRRYEIERRAYKHKERQERQRQRYSQQLDERIKRGDEIIAKAQEKKRRAEKAQENRQKQESDAGAAFARDVEEHRKRAEAIQLQRREKFLRQNYLRWNERAALVMQHLQDVFPPDGRCTLSGEKPCGFLPTLAPFLVNKRGNQQQKRANTVGSNKVS
Protein: Late expression factor 10 (Q9YKK9)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: Plays an essential role in viral DNA replication.
Subcellular location: Host nucleus {ECO:0000269|PubMed:27152613}.
Interaction partners:
Sequence:
MTNVWFATDVNLINCVLKDNLFLIDNNYIILNVFDQETDQVRPLCLGEINALQTDAAAQADAMLDTSSTSELQSNAST
Protein: Prospero homeobox 1 (U3KPY6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSP
Protein: Early transcribed membrane protein 10.3 (Q8IJM9)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKVSRHTVLLNIILIVSLLGCVLTLNLFSANDDKRALKDIDRTLEKLLRKKQIIISTAAVALAITLGGLFGSLGYKSWKNKNKSKDKVNDGSDSEELDSSKEDKDKDE
Protein: Ion-translocating oxidoreductase complex subunit G (EC 7.-.-.-) (Rsx electron transport complex subunit G) (P77285)
Organism: Escherichia coli (strain K12)
Function: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00479, ECO:0000305}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00479}.
Interaction partners:
- Ion-translocating oxidoreductase complex subunit B
- Ion-translocating oxidoreductase complex subunit C
- Ion-translocating oxidoreductase complex subunit E
- Ion-translocating oxidoreductase complex subunit D
- Ion-translocating oxidoreductase complex subunit A
- Endonuclease III lyase)
- FAD:protein FMN transferase
- UPF0125 protein RatB
- Probable pyruvate-flavodoxin oxidoreductase
- Protein RseC
Sequence:
MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAVKKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE
Protein: Hemolysin (Tly) (D7FF05)
Organism: Helicobacter pylori (strain B8)
Interaction partners:
Sequence:
MRLDYALFSQHLVNSREKAKALVLKNQVLVNKMVVSKPSFMVKEDDKIELIATNLFVSRAGEKLGAFLETHFVDFKGKVVLDVGASKGGFSQVALLKGAKKVLCVDVGKMQLDESLKNDQRIECYEECDIRGFKTPETIDLVLCDVSFISLYCILEAILPLSDEFLALFKPQFEVGRAAKRNKKGVVVDKEAILNALENFKNHLKTKDFQILKIQESLVKGKNGNVEFFIHFKRA
Protein: DENN domain-containing protein 2B (HeLa tumor suppression 1) (Suppression of tumorigenicity 5 protein) (P78524)
Organism: Homo sapiens (Human)
Function: May be involved in cytoskeletal organization and tumorogenicity. Seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Plays a role in EGFR trafficking from recycling endosomes back to the cell membrane.
Subcellular location: [Isoform 1]: Cytoplasm, cell cortex {ECO:0000269|PubMed:29030480}. Cell membrane {ECO:0000269|PubMed:29030480}. Recycling endosome {ECO:0000269|PubMed:29030480}. Note=Colocalizes with RAB13 and ITSN1 at cytoplasmic vesicles that are most likely recycling endosomes. Colocalizes with the cortical actin cytoskeleton. {ECO:0000269|PubMed:29030480}.
Interaction partners:
- Histatin-3
- Signal peptide, CUB and EGF-like domain-containing protein 2
- Syntenin-1
- Stromelysin-3
- Ras-related protein Rab-13
Sequence:
MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
Protein: Bleomycin hydrolase (EC 3.4.22.40) (Q9W3F6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR005700}.
Interaction partners:
Sequence:
MSDNNSGSGGGGSGGGGAGNNNSANSGKNSTHRFAETSVITNQLLEKWRKNFYSEPKNLLAQNVCSRVDPFDVCLSRKALETTNHVFNYKVETEGKPVTNQRSSGRCWLFAALNCIRLPFMKNYNLDEFEFSQAFLFYWDKIERCNYFLNNVVKTAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKKCFPESFSCESSLRMNAILKSKLREYARNLRVLMEKNPTDEEIACKIQEQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSIGPVSSLEFYERYVKPHFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTKSLKAGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAMVFTAVSVDKSGVAQKLRVENSWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDMDPIVLPAWDPMGTLAQ
Protein: Synaptonemal complex protein SYP-1 (G5EGS8)
Organism: Caenorhabditis elegans
Interaction partners:
- HORMA domain-containing protein
- Synaptonemal complex protein 3
- Zip homologous protein 2
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- Cyclin N-terminal domain-containing protein
Sequence:
MDNFTIWVDAPTEALIETPVDDQSSGFLRDEIMLTQQYVLEKLDEQTEQDKGEQTDEQAAKSRELASQVQTESQRMHDIKKELNVFKESCKSIELQLVSVKKSIPDRTKLQSGEKEKSLNEADYELSKFEDLLSSRERELTKIIQREQSRNNGEAKNECKRLREMIMAAKQKHEKLVELNSSCAMMQAKYDEMIIRQDQDREALEEGKLNLKASEEKLEQMREDCVTLRSQLFQFEASRSQDKTTEIEKEIEKITAETAKVRVENEQLKASLSKIKEDTKILKLKYEARQQEDIENKKLIEERKRSIIELLRRKIAEKKKSNTVKGSDRKKITSLKKAIAKEQEKLEKGKKELEQLQSSKTESDLEEEISAMQLEINDYDKQIKDAAKEHEKLFNQIKEQRAANGDQFNDTIDIVESDYSDRVVPPQPSVEVTPVHRQVSHDVFSAPLMTSTPLTAATRPLKRTRAADRLKTRAEAHTADVRRKRGGKK
Protein: Farnesyl pyrophosphate synthase (Q7KN61)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- isopentenyl-diphosphate Delta-isomerase
- Diphosphomevalonate decarboxylase
- Quemao, isoform A
- Hydroxymethylglutaryl-CoA synthase
- Protein farnesyltransferase subunit beta
- Alkyl transferase
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Mevalonate kinase
- All trans-polyprenyl-diphosphate synthase PDSS1
Sequence:
MFKLARMLLPQQRILASPLRLQRLISTSDEVNAEPIIKSMDTIGGLPTELVNEQKLKKTSRTLSTLQNHSVPIAARVTVSKDESRDFMAVFPDLVRDITTVTKAYNCSDAAKWFAQVLQYNVPRGKKNRGILTVLTYKNLVPTQDLTPENIKLAQYLGWCVEMLQSFFIISDDVMDNSTTRRGQPCWHKVENVGLTAINDALMIENAMYAILKKHFSHLDCYVALMELFHEITYITTCGQSLDQLNSNRCVSEFTMENYKAIVENKTAYYSFYLPFALALHLAGYKDAEAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGKIGTDIQDNKCSWLAVVAMQRANVEQKQIMVDCYGKEEPAKVERVKELYKELGLPSTYAIFEEESYNMIKTHIQQTSRGVPHQTFLQILNKIYQRDS
Protein: Ethylene responsive element binding protein 1 (A3FMG9)
Organism: Gossypium barbadense (Sea Island cotton) (Hibiscus barbadensis)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEMYPSTIDSDLMMLDSIRRLLLGESSDLRFTSSNDCTNVGAAPPMFCRSSSFSRLYPCLTDIWGDLPLKENDSEDMLVFGYLRDALTVGWAPSDHSSPTFPPIKPEPQEIPTETAVKEVPTVANAAVPTVVPAKGKHYRGVRQRPWGKFAAEIRDPAKNGARVWLGTFETAEDAALAYDKAAYRMRGSRALLNFPLRVNSGEPDPVRITSKRATPEPSTSSSSGSENGSPKRRRKVGSAAPVVAQAGLNMGFGA
Protein: Guanine nucleotide-binding protein alpha-11 subunit (O76584)
Organism: Caenorhabditis elegans
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Mediates the transduction of food and serotonin signals, which modulates the avoidance response to the odorant octanol. Has a role in lifespan to promote longevity.
Interaction partners:
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit beta-1
- Guanine nucleotide-binding protein subunit beta-2
- G Protein, Alpha subunit
- Guanine nucleotide-binding protein subunit alpha
- G protein gamma domain-containing protein
- Guanine nucleotide-binding protein alpha-16 subunit
- G Protein, Alpha subunit
- Parkin coregulated gene protein homolog
- Guanine nucleotide-binding protein alpha-13 subunit
Sequence:
MSAADMARKNSLINRQLEKEKIDSKKMLKILLLGGPECGKSTIFKQMKIIHMNGFSDLDYVNFRYLIYSNIMQSMDQLLEAAEFFHFPPDDSPSIRRALNHYKSYKVRYSTSEVELNRELADSLSKLYNAEFIKSVLNRKNELKLLDSAVYFLDDIDRISAHEYKPTEMDVLRARVPTTGITEIEFPFKQASLRMVDVGGQRSEQRKWIHCFDNVNGVLFIAAISGYNLYDEDEENRKDDGTPTKTNRLRYSMELFKRIANHQCFSKKTAMILFLNKIDIFKEKIGKYPLTTCFKNYKGVNAFEPACKYVTDRFSRLVSGDIQHEKPLYTHITNATDTRNIDRVFDSCMDVIFKISMEKVGFM