wanglab/gogpt-training-data huggingface dataset:
Protein: Probable xyloglucan glycosyltransferase 6 (EC 2.4.1.-) (Cellulose synthase-like protein C6) (AtCslC6) (Q9SRT3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose. Seems to work simultaneously with xyloglucan 6-xylosyltransferase. Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9LJP4}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cellulose synthase-like protein D1
- Xyloglucan galactosyltransferase MUR3
- Cellulose synthase-like protein D4
- Cellulose synthase-like protein B6
- Xyloglucan galactosyltransferase XLT2
- Xyloglucan 6-xylosyltransferase 2
- Xyloglucan 6-xylosyltransferase 1
- Protein trichome birefringence-like 5
- Cellulose synthase-like protein D5
- Probable xyloglucan 6-xylosyltransferase 5
Sequence:
MSRSQNEEFQQWWNKQRDRNNHDVLYAGDDEAFLTVEIRTPATVDPDKDRIRTRTVRQLSRLYLLKFKQLASSFLWIGNSFLYLVRTANRRIANDNPPSVSSSARLYRLIKGFLVVVVLLLCFELAAYFKGWHFTPPSVASAEVAVEVVYAWWLEIRASYLAPPLQSLTNVCIVLFLIQSVDRLVLVLGCFWIKLRRIKPVASMEYPTKLVGEGVRLEDYPMVIVQIPMCNEKEVYQQSIGAVCMLDWPRERMLVQVLDDSSELDVQQLIKAEVQKWQQRGVRIVYRHRLIRTGYKAGNLKAAMNCEYVKDYEFVAIFDADFQPPADFLKKTVPHFKGNEELALVQTRWAFVNKDENLLTRLQNINLSFHFEVEQQVNGVFINFFGFNGTAGVWRIKALEDCGGWLERTTVEDMDIAVRAHLCGWKFIYLNDVKCLCELPESYEAYKKQQYRWHSGPMQLFRLCFFDILRSKVSAAKKANMIFLFFLLRKLILPFYSFTLFCVILPLTMFFPEANLPSWVVCYIPGIMSILNIIPAPRSFPFIVPYLLFENTMSVTKFGAMISGLFKFDSSYEWVVTKKLGRSSEADLVAYAESGSLVESTTIQRSSSDSGLTELSKLGAAKKAGKTKRNRLYRTEIALAFILLAASVRSLLSAQGIHFYFLLFQGITFVIVGLDLIGEQVS
Protein: Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1) (Ribosomal-protein S6 kinase homolog 1) (P42818)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway. Mediates the phosphorylation of MRFs (e.g. MRF1).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20683442}. Nucleus {ECO:0000269|PubMed:20683442}.
Interaction partners:
- Small ribosomal subunit protein eS6z
- Regulatory-associated protein of TOR 1
- Serine/threonine-protein kinase TOR
- Regulatory-associated protein of TOR 2
- Small ribosomal subunit protein eS6y
- Peptidyl-prolyl cis-trans isomerase FKBP12
- 3-phosphoinositide-dependent protein kinase 1
- 3-phosphoinositide-dependent protein kinase 2
- Target of rapamycin complex subunit LST8-1
- Uncharacterized protein
Sequence:
MVSSQRPVPNKIQKQQYLSISPSNSVLKDDVELEFSDVFGPLPEEANDIAYDEPAVVYSRSHSLVGPCSLDSHSLKLTKLTLLETEDSIDLVECLEGESLKENDDFSGNDDSDNEKALEGDLVKVSGVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTDMSVLDSPASSPSSDPKANPFTNFTYVRPPPSFLHQSTTTL
Protein: Insulin receptor substrate 1 (IRS-1) (pp185) (P35570)
Organism: Rattus norvegicus (Rat)
Function: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P35568}. Nucleus {ECO:0000250|UniProtKB:P35568}. Note=Nuclear or cytoplasmic localization of IRS1 correlates with the transition from proliferation to chondrogenic differentiation. {ECO:0000250|UniProtKB:P35568}.
Interaction partners:
- Growth factor receptor-bound protein 2
- Insulin-2
- Insulin-like growth factor 1 receptor
- Tyrosine-protein phosphatase non-receptor type 11
- Insulin-1
- Insulin receptor
- Phosphatidylinositol 3-kinase regulatory subunit alpha
- Insulin receptor substrate 2
- Insulin-like growth factor 1
- Tyrosine-protein kinase JAK2
Sequence:
MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKAHHDGAGGGCGGSCSGSSGVGEAGEDLSYDTGPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRTKSQSSSSCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPNGHYILSRGGNGHRYIPGATMGTSPALTGDEAAGAADLDNRFRKRTHSAGTSPTISHQKTPSQSSVVSIEEYTEMMPAAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHHLERRGGHHRPDSSNLHTDDGYMPMSPGVAPVPSNRKGNGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGSCSPDIGGGSCSSSSISAAPSGSSYGKPWTNGVGGHHTHALPHAKPPVESGGGKLLPCTGDYMNMSPVGDSNTSSPSECYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSSSSGRLRYTATAEDSSSSTSSDSLGGGYCGARPESSVTHPHHHALQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQQQQQQQQQSSLHPPEPKSPGEYVNIEFGSGQPGYLAGPATSRSSPSVRCLPQLHPAPREETGSEEYMNMDLGPGRRATWQESGGVELGRVGPAPPGAASICRPTRSVPNSRGDYMTMQIGCPRQSYVDTSPVAPVSYADMRTGIAAEKVSLPRTTGAAPPPSSTASASASVTPQGAAEQAAHSSLLGGPQGPGGMSAFTRVNLSPNHNQSAKVIRADTQGCRRRHSSETFSAPTRAANTVSFGAGAAGGGSGGGSEDVKRHSSASFENVWLRPGDLGGASKESAPGCGAAGGLEKSLNYIDLDLVKDVKQHPQDCPSQQQSLPPPPPHQPLGSNEGSSPRRSSEDLSTYASINFQKQPEDRQ
Protein: Mediator of RNA polymerase II transcription subunit 31 (Hpr1 suppressor protein 1) (Mediator complex subunit 31) (P38633)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 9
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 1
- Mediator of RNA polymerase II transcription subunit 8
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 20
- Mediator of RNA polymerase II transcription subunit 7
Sequence:
MSSTNGNAPATPSSDQNPLPTRFEVELEFIQSLANIQYVTYLLTQQQIWKSPNFKNYLKYLEYWCNPPYSQCIVYPNCLFILKLLNGFMESAIVNEDGLLEGLDELPKIIQLQGPQWMNEMVERWAN
Protein: Transcription factor A, mitochondrial (H7BYN3)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix, mitochondrion nucleoid {ECO:0000256|ARBA:ARBA00004436}.
Interaction partners:
Sequence:
XELCTGCGSRLRSPFSFVYLPRWFSSVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKEVSITVVSLKCLLRISVRECIRARLDSCEDNLVLLIIQVF
Protein: Tryptophan synthase (EC 4.2.1.20) (O13831)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Probable anthranilate synthase component 1
- Anthranilate phosphoribosyltransferase
- Multifunctional tryptophan biosynthesis protein
- Chorismate synthase
- Putative aminodeoxychorismate synthase
- Histidinol-phosphate aminotransferase
- Threonine dehydratase, mitochondrial
- Aromatic amino acid aminotransferase C569.07
- Aromatic amino acid aminotransferase C56E4.03
- Aromatic amino acid aminotransferase C1773.13
Sequence:
MTEQIKKTFLKAKEENKNVLVTFVTCGFPNVDETIKIMQGLQNGGAGIIELGIPFSDAVADGPTICKGNEIALKNNITLEKVFETVKLARDAGVTIPIILMGYYNPIFSYGDAKTIQKAKEVGANGFIIVDLPPEEAVGFREECKKQGVSFVPLVAPSTTDRRMELLASVADSFIYVVSRMGSTGSSATGVINTALPQLCQRVRKFAGDTPLAVGFGVNTSEHFHQVGSVSDGVVVGSKIIDLILKAEPGTAATVVEEYCKYLTKEDPSAPVPKQFQSGGSVATAPPAAVVEPINEMYLPQKYGMFGGMYVPEALTQCLVELESVFYKALHDEKFWEEFRSYYEYMGRPSALDYAKRLTEYCGGAHIWLKREDLNHGGSHKINNCIGQILLAKRLGKNRIIAETGAGQHGVATAICAAKFGMKCTIYMGAEDCRRQALNVFRIRLLGAEVVPVTSGTQTLRDAVNEALKAWVEQIDTTHYLIGSAIGPHPFPTIVKTFQSVIGEETKAQMQEKRKKLPDAVVACVGGGSNSIGMFSPFKADKSVMMLGCEAGGDGVDTPKHSATLTMGKVGVFHGVRTYVLQREDGQIQDTHSISAGLDYPGVGPELSELKYTNRAEFIAVTDAQCLEGFRALCHLEGIIPALESSHAVYGGMELAKKLPKDKDIVITISGRGDKDVQSVAEQLPILGPKIGWDLRF
Protein: Zinc finger protein SNAI3 (Protein snail homolog 3) (Snail-related gene from muscle cells) (Zinc finger protein 293) (Q9QY31)
Organism: Mus musculus (Mouse)
Function: Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3'.
Subcellular location: Nucleus {ECO:0000269|PubMed:10606664}.
Interaction partners:
Sequence:
MPRSFLVKTHSSHRVPNYGKLETLREANGSCSACKELAGSRHLPDEEAPCNPSDPLQPWDSTSAVACISLPLLPNHRETLGVSGPEPQETSWVGPRAAQAPSVTLKDSFTLPPLLVLPTRWPPILGPDGALNEHLRAEGTSRVPGSFECIHCHRPYHTLAGLARHQQLHCHLPTGRAFTCRYCDKEYASLGALKMHIRTHTLPCICKVCGKAFSRPWLLQGHIRTHTGEKPYTCSHCSRAFADRSNLRAHLQTHVGTKKYRCAVCPKAFSRMSLLARHEEAGCCPGP
Protein: Protein LOW PSII ACCUMULATION 1, chloroplastic (Q9SRY4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Chaperone required for efficient photosystem II (PSII) assembly. Binds to psbA during de novo biogenesis of PSII.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:16531500}; Multi-pass membrane protein {ECO:0000269|PubMed:16531500}.
Interaction partners:
- Protein LPA2
- Protein PAM68, chloroplastic
- Zinc finger protein SHOOT GRAVITROPISM 5
- Chloroplast protein HCF243
- Protein LPA3
- Protein TILLER ANGLE CONTROL 1
- Protein indeterminate-domain 13
- Photosystem II stability/assembly factor HCF136
- Thylakoid membrane protein TERC, chloroplastic
- Inner membrane protein ALBINO3
Sequence:
MAVATAPSLNRHFPRRISNLYSRVKQRRPWLPPGDATLFNSRRNWDSHLFVYASSSSSPSSSPPSPNSPTDDLTAELCVNTGLDLFKRGRVKDALVQFETALSLAPNPIESQAAYYNKACCHAYRGEGKKAVDCLRIALRDYNLKFATILNDPDLASFRALPEFKELQEEARLGGEDIGDNFRRDLKLISEVRAPFRGVRKFFYFAFAAAAGISMFFTVPRLVQAIRGGDGAPNLLETTGNAAINIGGIVVMVSLFLWENKKEEEQMVQITRDETLSRLPLRLSTNRVVELVQLRDTVRPVILAGKKETVTLAMQKADRFRTELLRRGVLLVPVVWGERKTPEIEKKGFGASSKAATSLPSIGEDFDTRAQSVVAQSKLKGEIRFKAETVSPGEWERWIRDQQISEGVNPGDDVYIILRLDGRVRRSGRGMPDWAEISKELPPMDDVLSKLER
Protein: Transcriptional regulatory protein BtsR (P0AFT5)
Organism: Escherichia coli (strain K12)
Function: Member of the two-component regulatory system BtsS/BtsR, which is part of a nutrient-sensing regulatory network composed of BtsS/BtsR, the low-affinity pyruvate signaling system YpdA/YpdB and their respective target proteins, BtsT and YhjX. Responds to depletion of nutrients, specifically serine, and the concomitant presence of extracellular pyruvate. BtsR regulates expression of btsT by binding to its promoter region. Activation of the BtsS/BtsR signaling cascade also suppresses YpdA/YpdB-mediated yhjX induction.
Interaction partners:
- Sensor histidine kinase BtsS
- Sensor histidine kinase YpdA
- Pyruvate/proton symporter BtsT
- Uncharacterized MFS-type transporter YhjX
- Gamma-glutamyl phosphate reductase
- Transcriptional regulatory protein DcuR
- Uncharacterized protein YehS
- Transcriptional regulatory protein HprR
Sequence:
MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKPIDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRMSGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILRNGLTVPVSRRYLKSLKEAIGL
Protein: mitogen-activated protein kinase kinase (EC 2.7.12.2) (Q498S1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADQFSPEFVDFTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
Protein: MIP02960p (Rho GTPase activating protein at 1A, isoform C) (Rho GTPase activating protein at 1A, isoform F) (C1C560)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPPRPPPKNIRRVEPPTIPSQQLSSSPKRETYMINTMPSSSSGSLCIDSLGNSLERNIKPSDILRQKSSDNLDSKYSAKRKTTPELSKFVNVNNPELMEELGRKMVSKADSLEQTRRNDSSPSGCGSLGRTSSTPGRSLTPGRTGVGASPTGSLSKTGKLAMADSSSTSSLERRSCLQAVDADIGTESRESGANQRSVGSKESLTSQGISEVIKSYESVSSLSSESAKAVASQQSAAAGGALAECEPYYDSVPLDNGDGEYVFIKPGRTGSSSSRDDLSTPGSSILPLPNVADPESPGRTSNYVNIDFFLQQGIETRSSSLDSDGEYEGPPILRTISHDDQTTTQTTPGAIRKVCGNARGAKIRSILSSIIQSETIYVECLNKMMQYKKAIHATLTTSQPVIREEEENTIFFKIDELYDLHTGFLSDLKTIVSHEGGDVLIGEPFRRLAEMFDLYSAFLHNYKNAIETVKKCSANNPQFKKIVSTIVLNLQTEQSLTLEDLLHKPVARVQINALVFNDLLRETPNAHPDHQPLRQAQKIIQMFLNQFNVVNQRLPIESNRNLRRMVRNSFIVELVDGHRKLRHLFLFNDVIACAKYKALGRDRIDYELKWFIPLKDVSIYEEADPAVELKESSPANISQVKRNLRSVRDQLAMEVANSGSGAFRSGDKYRRKLADLESQLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWIDSILSLKQKCNLPGANTINSLEVTAFIVAMQKGMKTEMGSYLMRNTNDESLLVGDLYMGVHGLEGLEQANDLYICVEVDSYGHYFRKATTKKICRSQTPLWNESFMLELEGSQNVRILLYEAKERPLLKAKHILKLSLSWLTETTQPKSIKLTETLELGCSFRFIPGELFRGSTKPGALFGAKMSQVLK
Protein: F-box/kelch-repeat protein At3g24760 (Q3EB08)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F-box protein At5g52880
- F-box/kelch-repeat protein At2g24250
- F-box/LRR-repeat protein At1g67190
- F-box/kelch-repeat protein At1g64840
- Putative F-box protein At1g47730
- F-box protein At4g27050
- F-box protein At1g30790
- F-box/kelch-repeat protein At3g04660
- F-box/LRR-repeat protein At3g03360
- F-box protein SKIP19
Sequence:
MSDNNPEIESSTFNNLNIDVTESILYHLPIPSLVRFTLVSKQWRSLITSLPPSPSPSPSSPPWLFLFGIHNTSSFHNQSFAFDPLSNTWLRLPPSSSSSDHLVGSNRFLFTTAPRFSFSPILKPNWRFTSPVRFPRINPLLTVFTTLSNSSKLILVGGSSRIGGLVDIEERLAVQIYDPVLDSWELCSPLPADFRSGQDHQTLTSALFKRRFYVFDNYSCFISSFCLDSYTWSDVQTLKPPGLSFAYLNSCNGMLVLGGMCGFSFNLWSIEEGSMEFSEIAVMPEDLLFGLVDSDDEDDKFRSLKCAGSGNLVYVFNDDCHKKFPACVCEIGGGENGICSWRRVPCLPSPVNKFHKVVSFCSTVSITDVFHPEEARIGGSIRG
Protein: Pentatricopeptide repeat-containing protein At2g45350, chloroplastic (Protein CHLORORESPIRATORY REDUCTION 4) (O22137)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a major role in chloroplast RNA editing. Acts as a site-recognition transacting factor to recruit C-deaminase. Involved in single RNA editing events. Required for the edition of the site 1 of ndhD (ndhD-1 site corresponding to cytidine-2), which is a plastid-encoded subunit of the NADH-plastoquinone oxidoreductase. The interaction with DYW1 is required for its function in editing the ndhD-1 site.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:17015439, ECO:0000269|PubMed:23001034}.
Interaction partners:
- Pentatricopeptide repeat-containing protein DWY1, chloroplastic
- NAD
- 12S seed storage protein CRD
- Protein CHLORORESPIRATORY REDUCTION 42
- NAD
- Multiple organellar RNA editing factor 8, chloroplastic/mitochondrial
- Multiple organellar RNA editing factor 9, chloroplastic
- Toll/interleukin-1 receptor-like protein
- Multiple organellar RNA editing factor 3, mitochondrial
- Protein CHLORORESPIRATORY REDUCTION 7
Sequence:
MLVFKSTMECSISSTIHVLGSCKTSDDVNQIHGRLIKTGIIKNSNLTTRIVLAFASSRRPYLADFARCVFHEYHVCSFSFGEVEDPFLWNAVIKSHSHGKDPRQALLLLCLMLENGVSVDKFSLSLVLKACSRLGFVKGGMQIHGFLKKTGLWSDLFLQNCLIGLYLKCGCLGLSRQMFDRMPKRDSVSYNSMIDGYVKCGLIVSARELFDLMPMEMKNLISWNSMISGYAQTSDGVDIASKLFADMPEKDLISWNSMIDGYVKHGRIEDAKGLFDVMPRRDVVTWATMIDGYAKLGFVHHAKTLFDQMPHRDVVAYNSMMAGYVQNKYHMEALEIFSDMEKESHLLPDDTTLVIVLPAIAQLGRLSKAIDMHLYIVEKQFYLGGKLGVALIDMYSKCGSIQHAMLVFEGIENKSIDHWNAMIGGLAIHGLGESAFDMLLQIERLSLKPDDITFVGVLNACSHSGLVKEGLLCFELMRRKHKIEPRLQHYGCMVDILSRSGSIELAKNLIEEMPVEPNDVIWRTFLTACSHHKEFETGELVAKHLILQAGYNPSSYVLLSNMYASFGMWKDVRRVRTMMKERKIEKIPGCSWIELDGRVHEFFVDSIEVSSTL
Protein: Ubiquitin, putative (Q584D3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ubiquitin-conjugating enzyme E2, putative
- NEDD8-activating enzyme E1 catalytic subunit
- NEDD8-activating enzyme E1 regulatory subunit
- COP9 signalosome complex subunit 5
- JAB1/MPN/MOV34 metalloenzyme domain-containing protein
- Cullin 1, putative
- Ubiquitin carboxyl-terminal hydrolase
- Elongin-C
- PCI domain-containing protein
- COP9 signalosome complex subunit 4
Sequence:
MLLKVKTVSNKVIQITSLTDDNTIAELKGKLEESEGIPGNMIRLVYQGKQLEDEKRLKDYQMSAGATFHMVVALRAGC
Protein: Vacuolar protein sorting-associated protein 4 (EC 3.6.4.6) (BmVps4) (Vacuolar protein sorting 4) (D0FH76)
Organism: Bombyx mori (Silk moth)
Function: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane.
Subcellular location: Prevacuolar compartment membrane {ECO:0000250|UniProtKB:Q8VEJ9}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8VEJ9}. Late endosome membrane {ECO:0000250|UniProtKB:Q9UN37}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UN37}. Midbody {ECO:0000250|UniProtKB:Q9UN37}. Cytoplasm {ECO:0000269|PubMed:28973578}. Note=Membrane-associated in the prevacuolar endosomal compartment. Localizes to the midbody of dividing cells. {ECO:0000250|UniProtKB:Q9UN37}.
Interaction partners:
- 1110059p08rik-like protein
- Uncharacterized protein.
- Uncharacterized protein.
- Uncharacterized protein.
- Uncharacterized protein.
- Uncharacterized protein.
- Uncharacterized protein.
- Vps24
- Uncharacterized protein.
- Uncharacterized protein.
Sequence:
MTSSNTLQKAIDLVTKATEEDKNKNYEEALRLYEHGVEYFLHAVKYEAQGERAKESIRAKCLQYLDRAEKLKEYLKKDQKKKPVKDGESKSDDKKSDSDSDSDDPEKKKLQGKLEGAIVVEKPHVKWSDVAGLEAAKEALKEAVILPIKFPHLFTGKRIPWKGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKNLFDLARQHKPSIIFIDEIDSLCSSRSDNESESARRIKTEFLVQMQGVGNDMDGILVLGATNIPWVLDSAIRRRFEKRIYIALPEEHARLDMFKLHLGNTRHQLSEQDMKLLAAKSEGYSGADISIVVRDALMQPVRKVQSATHFKKISGPSPTDPNVIVNDLLTPCSPGDPGAIEMTWIDVPSDKLGEPPVTMSDMLRSLAVSKPTVNDDDMVKLRKFMEDFGQEG
Protein: GDSL esterase/lipase At3g05180 (EC 3.1.1.-) (Extracellular lipase At3g05180) (Q9MAA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
METLFHTLLRLLLFVAISHTLSPLAGSFRISNDFPAVFNFGDSNSDTGELSSGLGFLPQPSYEITFFRSPTSGRFCNGRLIVDFLMEAIDRPYLRPYLDSISRQTYRRGCNFAAAASTIQKANAASYSPFGFGVQVSQFITFKSKVLQLIQQDEELQRYLPSEYFFSNGLYMFDIGQNDIAGAFYTKTVDQVLALVPIILDIFQDGIKRLYAEGARNYWIHNTGPLGCLAQVVSIFGEDKSKLDEFGCVSDHNQAAKLFNLQLHGLFKKLPQQYPNSRFTYVDIFSIKSDLILNHSKYGFDHSIMVCCGTGGPPLNYDDQVGCGKTARSNGTIITAKPCYDSSKYVNWDGIHYTEAANRFVALHILTGKYSETASSLNL
Protein: Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1) (Q9DBR4)
Organism: Mus musculus (Mouse)
Function: Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength. Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning. Activates transcription of APP (By similarity).
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q92870}. Golgi apparatus {ECO:0000250|UniProtKB:Q92870}. Early endosome {ECO:0000250|UniProtKB:Q92870}.
Interaction partners:
- Amyloid-beta precursor protein
- Amyloid beta precursor like protein 1
Sequence:
MSEVLPADSGVGTLAVFMASSGSTDIANRNSPATPPNTLNLRSSHNELLNAEIKHSDAKNSTPPKCRKKYALTNIQAAMGLSDPAVQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNKNLSPAAVINLTSEKLEVKDPHPQESSGCEILPSQPRRTKSFLNYYADLETSARELGQNLGPCQGVGEEKAQPGPGQAPVVIGNGDLLPQKPNKPQSSPEDGQVATVSSSPETKKDHPKTGAKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETDIWSDHSFQTDPDLPPGWKRVNDIAGTYYWHIPTGTTQWERPVSIPADLHGSRKGSLSSVTPSPTPENEKQPWSDFAVLNGGKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHGDDDDSCSINSDPEAKCFAVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLSLENDMLSLVDPMDRSVLHSQPIVNIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAIATSLHEICSKIMAERKNAKALACSSLQERTNMSLDVPLQVDFPTPKTELVQKFRVQYLGMLPVDRPVGMDTLNSAIENLMTSSSKEDWPSVNMNVADATVTVISEKNEEEVLVECRVRFLSFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAANVSEAVQAACMLRYQKCLVARPPSQKVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTETP
Protein: A1-d protein (B-cell leukemia/lymphoma 2 related protein A1d) (O55179)
Organism: Mus musculus (Mouse)
Interaction partners:
- Bcl-2-related protein A1
- Bcl-2-like protein 11
Sequence:
MSEYEFMYIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVGAYKQVSSFVAEFIMNNTGEWIRRNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
Protein: LRR receptor-like serine/threonine-protein kinase FLS2 (EC 2.7.11.1) (Protein FLAGELLIN-SENSING 2 homolog) (OsFLS2) (Protein FLAGELLIN-SENSITIVE 2 homolog) (Q0JA29)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Recognizes flg22 from Pseudomonas aeruginosa and Acidovorax avenae. flg22 is a peptide derived from the bacterial flagellin N-terminus sequence. Does not recognize flg22 from Xanthomonas oryzae pv. oryzae (Xoo) or Xanthomonas oryzae pv. oryzicola (Xoc).
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- mitogen-activated protein kinase kinase kinase
- Os02g0255000 protein
- Os08g0254600 protein
- Os02g0789100 protein
- Os03g0758300 protein
- Os02g0627700 protein
- Os03g0646300 protein
- Os02g0773400 protein
- Os04g0643600 protein
- Os06g0207700 protein
Sequence:
MERNKFASKMSQHYTKTICIAVVLVAVLFSLSSAAAAGSGAAVSVQLEALLEFKNGVADDPLGVLAGWRVGKSGDGAVRGGALPRHCNWTGVACDGAGQVTSIQLPESKLRGALSPFLGNISTLQVIDLTSNAFAGGIPPQLGRLGELEQLVVSSNYFAGGIPSSLCNCSAMWALALNVNNLTGAIPSCIGDLSNLEIFEAYLNNLDGELPPSMAKLKGIMVVDLSCNQLSGSIPPEIGDLSNLQILQLYENRFSGHIPRELGRCKNLTLLNIFSNGFTGEIPGELGELTNLEVMRLYKNALTSEIPRSLRRCVSLLNLDLSMNQLAGPIPPELGELPSLQRLSLHANRLAGTVPASLTNLVNLTILELSENHLSGPLPASIGSLRNLRRLIVQNNSLSGQIPASISNCTQLANASMSFNLFSGPLPAGLGRLQSLMFLSLGQNSLAGDIPDDLFDCGQLQKLDLSENSFTGGLSRLVGQLGNLTVLQLQGNALSGEIPEEIGNMTKLISLKLGRNRFAGHVPASISNMSSLQLLDLGHNRLDGVFPAEVFELRQLTILGAGSNRFAGPIPDAVANLRSLSFLDLSSNMLNGTVPAALGRLDQLLTLDLSHNRLAGAIPGAVIASMSNVQMYLNLSNNAFTGAIPAEIGGLVMVQTIDLSNNQLSGGVPATLAGCKNLYSLDLSGNSLTGELPANLFPQLDLLTTLNISGNDLDGEIPADIAALKHIQTLDVSRNAFAGAIPPALANLTALRSLNLSSNTFEGPVPDGGVFRNLTMSSLQGNAGLCGGKLLAPCHGHAAGKKRVFSRTGLVILVVLIALSTLLLLMVATILLVSYRRYRRKRRAADIAGDSPEAAVVVPELRRFSYGQLAAATNSFDQGNVIGSSNLSTVYKGVLAGDADGGMVVAVKRLNLEQFPSKSDKCFLTELATLSRLRHKNLARVVGYAWEAGKIKALVLDYMVNGDLDGAIHGGAAAPPPAPSRWTVRERLRVCVSVAHGLVYLHSGYDFPVVHCDVKPSNVLLDGDWEARVSDFGTARMLGVHLPAAANAAAQSTATSSAFRGTVGYMAPEFAYMRTVSTKVDVFSFGVLAMELFTGRRPTGTIEEDGVPLTLQQLVDNAVSRGLDGVHAVLDPRMKVATEADLSTAADVLAVALSCAAFEPADRPDMGAVLSSLLKMSKLVGED