wanglab/gogpt-training-data huggingface dataset:
Protein: Tripartite motif-containing protein 49C (Tripartite motif-containing protein 49-like protein 2) (P0CI26)
Organism: Homo sapiens (Human)
Interaction partners:
- Tripartite motif-containing protein 49
Sequence:
MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLWLFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHREKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITGLRDRLNQFRVHITLHHEEANSDIFLYEILRSMCIGCDHQDVPYFTATPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYRKEKNQNEKIDGKEGLFLLGCIKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF
Protein: Diamine oxidase [copper-containing] (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) (Kidney amine oxidase) (KAO) (KDAO) (P19801)
Organism: Homo sapiens (Human)
Function: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:8144586}. Cell membrane {ECO:0000269|PubMed:8144586}; Peripheral membrane protein {ECO:0000305|PubMed:8144586}; Extracellular side {ECO:0000305|PubMed:8144586}.
Interaction partners:
- Histamine N-methyltransferase
- Aromatic-L-amino-acid decarboxylase
- Amine oxidase [flavin-containing] B
- Amine oxidase [flavin-containing] A
- Ornithine decarboxylase
- Histidine decarboxylase
- Spermidine synthase
- Aldehyde dehydrogenase family 3 member A2
- Guanidino acid hydrolase, mitochondrial
- Diamine acetyltransferase 1
Sequence:
MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
Protein: Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-) (Q8MSF5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Endoribonuclease.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- V-type proton ATPase subunit S1
- ATPase H
- GEO02534p1
- V-type proton ATPase subunit G
- V-type proton ATPase subunit E
- V-type proton ATPase subunit B
- V-type proton ATPase subunit H
- V-type proton ATPase subunit C
- RE60063p
- MTOR-associated protein MEAK7
Sequence:
MKICGPKLSLCGLIISVWGIVQLVLMGLFFYINSVALIEDLPLEEEYHSLEDFYAAANRAYNQNAYNCWIAACIYVLTLLLSAQQFYMNSRVTAN
Protein: Eater (Q9VB78)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- SR-CI
Sequence:
MWICRITIYSLLLGLVSAQICTVNVTRNIKGTAVNVQTRDCCKGYKKVRSSALRCLAQCKVNCGSGFCTKPNVCTCKKGYVNLNNDPSNRCVPYCKGCSRGTCQSPGRCICSARHLLDKTTNNCIPQCASGCPNGTCITPNNCSCNKGYKLNPTTQVCLPTCKDNCAAVNGFCAAPNRCECNPGFIPKPKSKSFECQPKCKNGCSNGVCRAPDKCECNKFYEKDIDGNCVPICENGCVNGNCTAPDVCQCLTGYTKIGHNVCLAVCPEGCQNGVCVAPNECSCNAGYTKLEGVCTPVCKDGCVNGFCASPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDEGYIKGTGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAPEKCSCDEGYSKETGNSCKPICSNGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCIAPGKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKPICSKGCENGFCEAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCIAPGKCSCDEGYSRETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETEISCAPFCKDGCVNGLCVSPDFCKCDDGYIFVEESKSCQLDKELLGDYSDCDKNCRNGTCVEGICTCSKQYKLHRNEDDNNLICLPICEPECLNGLCEFPGSCVCWDGESPIDGYSCQSMDSLGSLTGHEKSERHLKWVFITIVSMAFILAIITTMLIIYIFRKRSYHVDKNEREFGVYFSPNKVDIIRA
Protein: RNA helicase (EC 3.6.4.13) (A0A2R8Y7T2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Protein: Uncharacterized protein (Q57WQ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLRPHCTERVPSCIDSGSGNVVFALHPDPFGNQVCWGSCVVTRNLELVFSRPSYGASRLKIPGAHEKGDTSQFFCFSCVNATKLLGVPIEPKWVMSYDLSSNSYSEETEMSHANSVLQGLPTVAMLLMTNNAETKLLVVNPVLHVEKKEQIITYRATLLTSPDSVQHVVMCRGGRVVLLLEQCVGGNVASQCFGLLIRDGQPHAPFKSVRLTVPGEFIASMPAQRIICARARRPLGQTTHAMIETVDTEVTTFTDHGVVIVFRIGVSDAEPQRVTCVWVSHLFRRSESQKKLLRPLGVVERWNTTMSFKQATGLAGTKPPLPPLGCEVPQQLQGFKTHSSIICASSNGALILVAKPNSPDAFIACLGASVHERSSANAGVGVSLPPSLNLCDASWISGPLCGFLLLGNDDGRKVLSLYFLPLTGESPRRVHIEQTDCEWANIENRNVRFFSLSTVVNIFGVPQLRISLLFSQHRKRGDTQIEDWSELRTCLFSFPTVASLSSVEDPAHVSTLVYCTGLAAFEAIPWPVGTSARTKCTDEVHGFGDVQLSTEAALESQLKRWPHLEESGIEFFCGLIHEMIQRLTTSVQRCRFVDSGFGNRAVAALVAVFQGVAEAFVTLGVAYSSTLLKRYLCYVHSILVILRQALTVMGQYGAISACFSAVAPFAHLDSSGSEGELQPEWRALLGALFDEALAHTCAYPSLAQALLPHCSAGVKQIMEAGRRMEQWTHKQQETAATTLTTADRGESTQVRTLQEVLSLVRNGAPALSMLSPADVCCASRRLFFSDGIDTVQAFLKSFVGDYWMNCPDIQAVCKEYETVKEDMDIVLQCR
Protein: DnaJ heat shock protein family (Hsp40) member C7 (K7EK03)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MWKLLRGLSREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKA
Protein: Nuclear fallout, isoform G (M9NDQ8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Midbody {ECO:0000256|ARBA:ARBA00004214}. Recycling endosome membrane {ECO:0000256|ARBA:ARBA00004654}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004654}.
Interaction partners:
Sequence:
MAPMPRIQLPNGNSSIKASTNDFLFAETMSGDSSPTPSSPPSSTAGVAKSQCSSLSDGESFEGYGENEYPTQLREARSSNSNGSHNMSNHINNNSNISVGNNSGHNHSGHSNDGNNNLNGSTGVELDLAPHVGSSTPQDDDELNIMPRDNWARRSLRRTPTSNPDSLSQRRWGSMRHSGRRQISSNALASQLYRSSSFNSSGRSSNCDTTEDMYSDISLENRHDYDYRLELLQRKVDDLSDTQNIAEDRTTRTKTEYAVLQARYHMLEEQYRESELRAEERLAEEQKRHREILARVEREASLQNENCQMKIRATEIEATALREEAARLRVLCDKQANDLHRTEEQLELARDQIGVLQQEHEEQAQALRRHEQEKKSTEELMLELGRELQRAREESGARAMPTTSPESIRLEELHQELEEMRQKNRTLEEQNEELQATMLTNQATMLTNGVEQGRHLLNGTLNSLAQELEEMSQAQDSVDSATLASLSQLQQAFQEKEDENVRLKHYIDTILLNIVENYPQLLEVKPMERK
Protein: Aldolase-type TIM barrel family protein (Putative transaldolase) (Transaldolase-like protein) (Q9LYR4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Transketolase-1, chloroplastic
- Transketolase-2, chloroplastic
- Glucose-6-phosphate isomerase, cytosolic
- Glucose-6-phosphate isomerase 1, chloroplastic
- Triosephosphate isomerase, chloroplastic
- Triosephosphate isomerase, cytosolic
- Fructose-1,6-bisphosphatase, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic
- Fructose-1,6-bisphosphatase 1, chloroplastic
Sequence:
MATISNLANLPRATCVDSKSSSSSSVLPRSFVNFRALNAKLSSSQLSLRYNQRSIPSLSVRCSVSGGNGTAGKRTTLHDLYEKEGQSPWYDNLCRPVTDLLPLIARGVRGVTSNPAIFQKAISTSNAYNDQFRTLVESGKDIESAYWELVVKDIQDACKLFEPIYDQTEGADGYVSVEVSPRLADDTQGTVEAAKYLSKVVNRRNVYIKIPATAPCIPSIRDVIAAGISVNVTLIFSIARYEAVIDAYLDGLEASGLDDLSRVTSVASFFVSRVDTLMDKMLEQIGTPEALDLRGKAAVAQAALAYKLYQQKFSGPRWEALVKKGAKKQRLLWASTSVKNPAYSDTLYVAPLIGPDTVSTMPDQALEAFADHGIVKRTIDANVSEAEGIYSALEKLGIDWNKVGEQLEDEGVDSFKKSFESLLGTLQDKANTLKLASH
Protein: Hemopexin (Q6PHG2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P20058}.
Interaction partners:
- Tissue inhibitor of metalloproteinase 2.
- Alpha-2-HS-glycoprotein 1.
- Protein AMBP
- Alpha-2-HS-glycoprotein 2
- Fibrinogen alpha chain
Sequence:
MRLIQALSLCLALSLSLAAPPQHKEDHSHKGKPGGEGHKHELHHGAQLDRCKGIEFDAVAVNEEGVPYFFKGDHLFKGFHGKAELSNKTFPELDDHHHLGHVDAAFRMHSEDSPDHHDHQFFFLDNMVFSYFKHKLEKDYPKLISAVFPGIPDHLDAAVECPKPDCPNDTVIFFKGDEIYHFNMHTKKVDEKEFKSMPNCTGAFRYMGHYYCFHGHQFSKFDPMTGEVHGKYPKEARDYFMRCPHFGSKTTDDHIEREQCSRVHLDAITSDDAGNIYAFRGHHFLSITGDKFHSDTIESEFKELHSEVDSVFSYDGHFYMIKDNDVFVYKVGKPHTHLEGYPKPLKDVLGIEGPVDAAFVCEDHHVVHIIKGQSIYDVDLKATPRKLVKEGTITQFKRIDAAMCGPKGVTVVIGNHFYNYDSVQVMLMAKIMPEQQKVSQQLFGCDH
Protein: Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain] (O94925)
Organism: Homo sapiens (Human)
Function: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain.
Subcellular location: [Isoform 1]: Mitochondrion {ECO:0000250|UniProtKB:P13264}. Cytoplasm, cytosol {ECO:0000269|PubMed:22228304}. Note=The 74-kDa cytosolic precursor is translocated into the mitochondria and processed via a 72-kDa intermediate to yield the mature 68- and 65-kDa subunits. {ECO:0000250|UniProtKB:P13264}.; SUBCELLULAR LOCATION: [Isoform 3]: Mitochondrion {ECO:0000269|PubMed:22228304}.; SUBCELLULAR LOCATION: [Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix {ECO:0000250|UniProtKB:P13264}. Note=Produced by the proteolytic processing of the 74-kDa cytosolic precursor. {ECO:0000250|UniProtKB:P13264}.; SUBCELLULAR LOCATION: [Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix {ECO:0000250|UniProtKB:P13264}. Note=Produced by the proteolytic processing of the 74-kDa cytosolic precursor. {ECO:0000250|UniProtKB:P13264}.
Interaction partners:
- Glutamate dehydrogenase 1, mitochondrial
- Glutamine synthetase
- Glutamate dehydrogenase 2, mitochondrial
- Delta-1-pyrroline-5-carboxylate synthase
- Glutamate decarboxylase 1
- Glutamate decarboxylase 2
- Amidophosphoribosyltransferase
- Glutamine--fructose-6-phosphate aminotransferase 1
- Glutamine--fructose-6-phosphate aminotransferase 2
- Multifunctional protein CAD
Sequence:
MMRLRGSGMLRDLLLRSPAGVSATLRRAQPLVTLCRRPRGGGRPAAGPAAAARLHPWWGGGGWPAEPLARGLSSSPSEILQELGKGSTHPQPGVSPPAAPAAPGPKDGPGETDAFGNSEGKELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNLDGLL
Protein: Ankyrin repeat domain-containing protein 50 (Q9ULJ7)
Organism: Homo sapiens (Human)
Function: Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1.
Subcellular location: Endosome {ECO:0000305}.
Interaction partners:
- Protein C10
- Vacuolar protein sorting-associated protein 29
- Sorting nexin-27
- Vacuolar protein sorting-associated protein 35
Sequence:
MTNPWEEKVCKMAQTSLLQGKQFYCREWVFHKLQHCLQEKSNCCNSAVNAPSLVMNSGNNASGVSGKGAAWGVLLVGGPGSGKTALCTELLWPSSPASLQRGLHRQALAFHFCKAQDSDTLCVGGFIRGLVAQICRSGLLQGYEDKLRDPAVQSLLQPGECERNPAEAFKRCVLLPLLGMKPPQQSLYLLVDSVDEGCNITEGEQTSTSLSGTVAALLAGHHEFFPPWLLLLCSARKQSKAVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQFAKVQPILNVILAACRPLTITELYHAVWTKNMSLTLEDFQRKLDILSKLLVDGLGNTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCQAKNLTPLEAQEFALHLINSNLQLETAELALWMIWNGTPVRDSLSTLIPKEQEVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVHTMEQKPLQSLSSKVQSLTIKSNSSGSTGGGDMQPSLRGLPNGPTHAFSSPSESPDSTVDRQKSSLSNNSLKSSKNSSLRTTSSTATAQTVPIDSFHNLSFTEQIQQHSLPRSRSRQSIVSPSSTTQSLGQSHNSPSSEFEWSQVKPSLKSTKASKGGKSENSAKSGSAGKKAKQSNSSQPKVLEYEMTQFDRRGPIAKSGTAAPPKQMPAESQCKIMIPSAQQEIGRSQQQFLIHQQSGEQKKRNGIMTNPNYHLQSNQVFLGRVSVPRTMQDRGHQEVLEGYPSSETELSLKQALKLQIEGSDPSFNYKKETPL
Protein: A-kinase anchoring protein 13 (A8MYJ1)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MYERHKRRYSLCDISKVDRTVDVVLLKINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSDSDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADPGDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSFSLEGLTGGAGVGNKPSSSLEVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFHSTFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSSIPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETATTPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESWSRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVDKSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGRLKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLNRDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAINEVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKRNSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQVSHPHTKLMRIPSFFPSPEEPPSPSAPSIAKSGSLDSELSVSPKRNSISRTHKDKGPFHILSSTSQTNKGPEGQSQAPASTSASTRLFGLTKPKEKKEKKKKNKTSRSQPGDGPASEVSAEGEEIFC
Protein: Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2) (O55207)
Organism: Rattus norvegicus (Rat)
Function: Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11498538}. Cell membrane {ECO:0000269|PubMed:11498538}. Presynapse {ECO:0000269|PubMed:11498538}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11498538}. Membrane raft. Note=Localizes at presynapse terminals in brain and at bundles of microtubules surrounding the nucleus in the elongating spermatids corresponding to the manchette (PubMed:11498538). Translocates from the cytoplasm to membrane ruffles in a RAC1-dependent manner (PubMed:11498538). {ECO:0000269|PubMed:11498538}.; SUBCELLULAR LOCATION: [Isoform 2A]: Mitochondrion {ECO:0000269|PubMed:10357812}. Note=Interaction of isoform 2A with SYNJ2BP/OMP25 results in localization to the mitochondrion (PubMed:10357812). {ECO:0000269|PubMed:10357812}.
Interaction partners:
- Endophilin-A1
- Endophilin-A2
- Phosphatidylinositol-3-phosphatase SAC1
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Inositol polyphosphate-4-phosphatase type I A
- Synaptojanin-1
- Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
- Type II inositol 3,4-bisphosphate 4-phosphatase
- Inositol polyphosphate 5-phosphatase OCRL
- Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
Sequence:
MALSKGLRLLARLDPTGPSSVLLEARGRGDCLLFEAGAVATLAPEEKEVIKGLYGKPTDAYGCLGELSLKSGGVPLSFLVLVTGCTSVGRIPDAEIYKITGTEFYPLQEEAKEEDRLPALKKILSSGVFYFAWPNDGACFDLTIRAQKQGDDCSEWGTSFFWNQLLHVPLRQHQVNCHDWLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQAIYMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFERHMVLLKEQYGQQVVVNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLKLHWDDFGVFAKGENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKPITDRFVESFKAMWSLNGHGLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALLGLGSNKQNSLSGMLDGKATPRILKAMTERQSEFTNFKRIQIAMGTWNVNGGKQFRSNLLGTTELTDWLLDAPQLSGAVDSQDDGGPADIFAVGFEEMVELSAGNIVNASTTNRKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLMEFDQLQLQKSSGKIFKDFHEGTINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDANIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVIVNLQSPTLEERNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDVLEDDEDYLADEFGQPVVSDSELGGDDSSDTMSASTPASKSPALAKKKQHPTYKDDADLMTLKLELEVAGNFRHRSPSRSLSVPNRPRPPHPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLLEAGGGVPESAPGATPLRNQGSSKPEASLGPPVLPRRPVPRVPTMKKPTLRRTGKPMLPEEQCEQQPVHFTMASQEMNLETPPPITAPIPPVPKPRTFQPGRGVERRPSGGKPEPDDAPPVTGAVELSSPEAPEAPSLAPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTCSSSSPSPPKPDTPLLYPQMALGTSSAISPETDGPRVTEPEAASFHGDYPDPFWSLLHHPKLLNNNTWLSKSSEPLDLGSRTPERTHTDSAQVNASVVERGLPPDHGGKDFSHWMAASNKDKRTTLGV
Protein: Probable E3 ubiquitin-protein ligase LUL3 (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase LUL3) (Protein LOG2-LIKE UBIQUITIN LIGASE 3) (RING finger protein 398) (Q84ME1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates (in vitro).
Interaction partners:
- Zinc finger CCCH domain-containing protein 34
- U-box domain-containing protein 30
- Protein DA1-related 2
- AT5g17440/K3M16_10
- E3 ubiquitin-protein ligase RHA2A
Sequence:
MGISLSKRRRDNNNNHHHPHHNPPYYYSDPPPQQPPPQNGYSYSHNYPVSTPQLSLPPPPAQPPSSSQPPPSQISYRPYGQNYHQNQYYPQQAPPYFTGYHHNGFNPMMRPVYFGPTPVAVMEPPAPYVEHQTAKKVKNDVNVNKATVRLVADDLNPGHYLVSFVFDALFDGSFTIIFFGEEESKCTIVPHLPEAFPPIKVPFQKGAGQKFLQAPGTGIDLGFFSLDDLSKPSPEEVYPLVISAETVISPSSVSEEPLVHKQITQAVLEKTNDGSFKVKVMKQILWIEGERYELQELYGIDNSITQGTAASGLEDTGGKECVICLTEPKDTAVMPCRHLCLCSDCAEELRFQTNKCPICRQPIHELVKIKVESSDEQH
Protein: DNAJ heat shock N-terminal domain-containing protein (F4ICC0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAKETPASSSMPSGLKAYTVPIFLFVLAMFFQLFLLPRSFPPSHYDGTQFSKLAFSLDYFLVLGVKMYSSVDDVKDAYQTVASKWDSGSGVSLPADFVKIQYAYELLTNLVWKRDYDLYAIDESVHIIEELEKQYAVEDFAKIKLPLLEVVSYEPEREGFMSITSQDFASKFQDSKPWLIQVYSSGSNSSAQFATVWRRIVALLDGVANHAMLELGDVQLVTYLAEKKPTGQVFFRKGLPSIFSFPPNCKTADCLIRFEGELSADAITDWFATTVLGLPRVFYHTKETLVSKFLSKVPPNKVKVILFSQTGERATPIVRQAAKDYWNFASLSHVLWREEDASFWWNALEVESAPAIVIMKDPGSKPVVYHGSGNRTWFLDILEQNKQLLLPQLRSTTSMELGCDARGYSRAGYDKVTWYCAILVGRQSVELNKMRETMCRVQDALSKYDDSDDASKDPSITPAASAHKSKRLSFAWLDGEAQNKYCFFYVQSETSYDTCGTRRAPIDVPRILIVRYHRNATETANAEQKSSKWPKTVWQSEADDVDPAAQLVVSYDGTAEIPQIIKWLSKMVDDGDNRNLPFYRAKTPELVPESAEPMRSGVPKTVKATQKLLSLWNRIKDYLADPRMGPTLLLGALLSAGNVWWMRSRSSTQQPAQTNQPSPNQPADNVEEKKKKERKREQRRRNAKEEEVPASITDNEPKDAVQILSSGSDSD
Protein: Cell surface glycoprotein CD200 receptor 1 (CD200 cell surface glycoprotein receptor) (Cell surface glycoprotein OX2 receptor 1) (Q9ES57)
Organism: Mus musculus (Mouse)
Function: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- OX-2 membrane glycoprotein
- Leukocyte surface antigen CD47
- Fractalkine
- Docking protein 2
- B-cell receptor CD22
- CX3C chemokine receptor 1
- Triggering receptor expressed on myeloid cells 2
- Tyrosine-protein phosphatase non-receptor type substrate 1
Sequence:
MFCFWRTSALAVLLIWGVFVAGSSCTDKNQTTQNNSSSPLTQVNTTVSVQIGTKALLCCFSIPLTKAVLITWIIKLRGLPSCTIAYKVDTKTNETSCLGRNITWASTPDHSPELQISAVTLQHEGTYTCETVTPEGNFEKNYDLQVLVPPEVTYFPEKNRSAVCEAMAGKPAAQISWSPDGDCVTTSESHSNGTVTVRSTCHWEQNNVSDVSCIVSHLTGNQSLSIELSRGGNQSLRPYIPYIIPSIIILIIIGCICLLKISGFRKCKLPKLEATSAIEEDEMQPYASYTEKSNPLYDTVTKVEAFPVSQGEVNGTDCLTLSAIGI
Protein: 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) (P74498)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- Sll1752 protein
- Glycerol-3-phosphate acyltransferase
- Slr2060 protein
- Phosphate acyltransferase
- Phosphatidate cytidylyltransferase
- Uncharacterized protein sll0036
- Diacylglycerol kinase
- Glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate dehydrogenase [NAD
- Bifunctional pantoate ligase/cytidylate kinase
Sequence:
MDSEINHRGGLSAPRPRETSLNLALYRGLKWGVVRPLLHGLFQAQVYGQELVPTRGPALVVSNHASYFDPPFLSCAMARPVAFMAKEELFNVPLLGPAIRLYGAYPVKRGSGDRGALRAALTALGDGWLVGVFLEGTRTKDGRIHQPKLGAAMIAAKAQVPIIPVSLGGVEQIFQPGSPWPHPVPLTIRIGKAIAPPVKNRKPELEAVTKACQAQIHEMLDLGRD
Protein: DNA recombination protein RmuC homolog (Q92SH7)
Organism: Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Interaction partners:
Sequence:
MEPVPFSFDQPLFLIGTLPVTAGHLVTTAALLVVLFSAIMVRRARSARATGREEQMSALIAAQTEMQGRIAAMTEVLGARQAELNQSLSQRIDGMTHRIGASISEQTKATHENLRRLQERLAVIDNAQNNIQSLAKDMAGLQSILANKQTRGAFGQSRMEAIVADGLPMGAFAFQATLSNGARPDCTIRMPNGQPPLVIDAKFPLEAWNSMRDAASAERRQQAAQAFRRDMEVHIRDIAGKYLLPGETQDTAFLFVPSESIFAEIHEHFEAVVQKAHRQRIVIVSPSLLLLSIQVIQAILKDARMREQAHLIQSEVVRLMEDLSRLDERVRKLQGHFAMTQKDVEDILISSDKLTRRGAKIEALELQAEADPRQGEKPGDGSGRPMDGRMGQLKLRVVDED
Protein: T. brucei spp.-specific protein (Q57W30)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSAQVPNRGDSQDSMDNVTLTSERLLWTARTVTGLKQPATTAVSDGSGCETSGSGAAGGTGGLTEPTDSPATSECTLTWNSLMTAVFQQQVNEMRSQRAATKRTRSDDRVSQDRIFCLGEEEGRNSIPLDAQRTGKCHRLDLTPSTVRAHAPQSAGGESMLSPEGVQRRLSLHLLGRLSSSLPTLTEQSPVAAVAQGRNSTSSIASVPGTAASASAQPRPPTIGTPTPTPLRRYGDPSSQMSLLQDTDPPTESRPLLSQPGRSIPSPSTPLWATQDEAGDEGVLLDELDGNIIATDDNNSNTLNVGNDDDDIIVRVPLRRRPLSLQVSSLPFMSFPDTAAALQVREGGDRQLEGQGRSEAGRRMSVEEWAQQMNEFFTRVDERTLHTISID
Protein: Arylsulfatase A (Q32KK2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Galactocerebrosidase
- 2-hydroxyacylsphingosine 1-beta-galactosyltransferase
- Arylsulfatase B
- Alpha-galactosidase
- Sialidase-3
- Sialidase-2
- Sialidase-1
- Sialidase-4
- Arylsulfatase G
- Formylglycine-generating enzyme
Sequence:
MGALGTLVLALAAGLSTASPPNIMLIFADDLGYGDLGSYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRSGMYPGVLGPSSQGGLPLEEVTLAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPDITCSGGCDQGLVPIPLLANLTVEAQPPWLPGLEARYVSFSRDLMADAQRQGRPFFLYYASHHTHYPQFSGQSFTKRSGRGPFGDSLMELDGAVGALMTAVGDLGLLGETLVIFTADNGPELMRMSDGGCSGLLRCGKGTTFEGGVREPALVYWPGHITPGVTHELASSLDLLPTLAALTGAPLPNITLDGVDISPLLLGTGKSPRNSVFFYPPFPDEIHGVFAVRNGKYKAHFFTQGSAHSDTTPDPACHAANRLTAHEPPLLYDLSKDPGENYNLLDSTEEVSPEALQALKHIELLKAEYDAAMTFSPSQIAKGEDPALQICCQPSCTPHPVCCHCPDSHS