wanglab/gogpt-training-data huggingface dataset:
Protein: Legumain (EC 3.4.22.34) (Protease, cysteine 1) (O89017)
Organism: Mus musculus (Mouse)
Function: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation.
Subcellular location: Lysosome {ECO:0000269|PubMed:21292981, ECO:0000269|PubMed:9742219}.
Interaction partners:
- Cystatin E/M
- H-2 class II histocompatibility antigen gamma chain
- Cathepsin B
- Cathepsin S
- Procathepsin L
- Cathepsin Z
- Dipeptidyl peptidase 1
Sequence:
MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAGFGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPIDRIEMAMDKVCLSHY
Protein: TIR domain-containing adapter molecule 1 (Toll-like receptor adaptor molecule 1) (Q1LUQ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- TNF receptor-associated factor 6
- Toll-like receptor 3
- Interferon regulatory factor 3
- Interleukin-1 receptor-associated kinase 4.
- Toll-like receptor 4b, duplicate a.
- Toll-like receptor 4
- Toll-like receptor 4
- TNF receptor-associated factor
- Interleukin-1 receptor-associated kinase 1
- Receptor
Sequence:
MAEGGMKPSEGGCPNLGKVFEILSQAPQERLFSLTYKMGRKPTEELVHAMCLIFLKKHEAAHAKLTAIKDSRVGNYLAEMIKTHGERLNCSHIGGFMQTDVNSLLDIARIFAILVQESLCDKSHRDKAYCKAVESCKTAGLLSLDIEEEVKQVCGPDVISTSNSELPTEMCNPNSLKVSDINPDPLPPNSNLDVSSYYLEISSPTASEGNIEESKPMSLHTPTEFKSQNNLRSCHDKSTNIFANSQAQTAVVNDTASSNRCRHDSRPSQFVMSKNTNFSSSPNDGAKPKAQPINANDRKPPTQDNSFHPTLLSDIDETFYAFVILHEAEDADEAQRLREKLEGIISANGATFSEDFAQAGRSTLRCIEDAIDNSAFVLLLLTQNFKSNQSMTTTDSAIVNSLEHHHKLNSVIPLLPRENRLSRKNIPLVLQTKVPLDESNRTFERKALKALSQDAVEKQRKIWMKKQTLKKLEEEYKRRQEENFINANLRLEREKLARLKLESESPHNNMFHSSSAQPPSCGPMLQQHDSWPQKPSYIHIENAQNIMIGNHSTMNFEHTKSSAEES
Protein: Alkylated DNA repair protein (AlkB homolog), putative (Q57US9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEDPVRCECQKHAQDDGYSQGELLPLTAFRQVEKRYKLYRYDRRTSRRLQVPETDFSDVVDFRNLEANTAANLACISTRECHEDDRLVKCCTFAGVPGMEVFPNFLTDAEQQEFCRAALLEYGDSRRHPNHLSTHASEPRETTRYEPPMRWATVGFSYQWSSKSYCKEKYSHFPRRLRKCVERIARLCNVSQPYEPQTSIVNYFPVGAMMMAHQDVSEEVLQQPLISISLGCSCVFLMGTESRDDTPCAFWLRSGDVIVVSGASRTAYHGVPRIMDDCPQYLCPQNETEEEEGEFYWREQMRHLRVNINVRQVYPDRCEFLNE
Protein: Protein Tat (Transactivating regulatory protein) (P04610)
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1)
Function: Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongation by the RNA polymerase II (RNA pol II) complex, thereby increasing the level of full-length transcripts. In the absence of Tat, the RNA Pol II generates short or non-processive transcripts that terminate at approximately 60 bp from the initiation site. Tat associates with the CCNT1/cyclin-T1 component of the P-TEFb complex (CDK9 and CCNT1), which promotes RNA chain elongation. This binding increases Tat's affinity for a hairpin structure at the 5'-end of all nascent viral mRNAs referred to as the transactivation responsive RNA element (TAR RNA) and allows Tat/P-TEFb complex to bind cooperatively to TAR RNA. The CDK9 component of P-TEFb and other Tat-activated kinases hyperphosphorylate the C-terminus of RNA Pol II that becomes stabilized and much more processive. Other factors such as HTATSF1/Tat-SF1, SUPT5H/SPT5, and HTATIP2 are also important for Tat's function. Besides its effect on RNA Pol II processivity, Tat induces chromatin remodeling of proviral genes by recruiting the histone acetyltransferases (HATs) CREBBP, EP300 and PCAF to the chromatin. This also contributes to the increase in proviral transcription rate, especially when the provirus integrates in transcriptionally silent region of the host genome. To ensure maximal activation of the LTR, Tat mediates nuclear translocation of NF-kappa-B by interacting with host RELA. Through its interaction with host TBP, Tat may also modulate transcription initiation. Tat can reactivate a latently infected cell by penetrating in it and transactivating its LTR promoter. In the cytoplasm, Tat is thought to act as a translational activator of HIV-1 mRNAs.
Subcellular location: Host nucleus, host nucleolus {ECO:0000255|HAMAP-Rule:MF_04079}. Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04079}. Secreted {ECO:0000255|HAMAP-Rule:MF_04079}. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type. {ECO:0000255|HAMAP-Rule:MF_04079}.
Interaction partners:
Sequence:
MEPVDPRLEPWKHPGSQPKTACTTCYCKKCCFHCQVCFTTKALGISYGRKKRRQRRRPPQGSQTHQVSLSKQPTSQPRGDPTGPKE
Protein: Aquaporin TIP3-1 (Tonoplast intrinsic protein 3-1) (ZmTIP3-1) (ZmTIP3;1) (Q9ATL7)
Organism: Zea mays (Maize)
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Tonoplast.
Interaction partners:
Sequence:
MSTGVRPGRRFTVGRSEDATHPDTIRAAISEFIATAIFVFAAEGSVLSLGKMYHDMSTAGGLVAVALAHALALAVAVAVAVNISGGHVNPAVTFGALVGGRVSLVRAVLYWVAQLLGAVAATLLLRLATGGMRPPGFALASGVGDWHAVLLEAVMTFGLMYAYYATVIDPKRGHVGTIAPLAVGFLLGANVLAGGPFDGAGMNPARVFGPALVGWRWRHHWVYWLGPFLGAGLAGLVYEYLVIPSADAAVPHAHQPLAPEDY
Protein: Cerebellin-4 (Cerebellin-like glycoprotein 1) (Q8BME9)
Organism: Mus musculus (Mouse)
Function: Acts as a synaptic organizer in specific subsets of neurons in the brain. Essential for the formation and maintenance of inhibitory GABAergic synapses. Promotes the development of dendrite-targeting inhibitory GABAergic synapses made by somatostatin-positive interneurons. May contribute to the function of ventral medial habenula region of the brain implicated in the regulation of anxiety-related behaviors. May play a role in CBLN3 export from the endoplasmic reticulum and secretion.
Subcellular location: Secreted {ECO:0000269|PubMed:17030622, ECO:0000269|PubMed:17331201, ECO:0000269|PubMed:29782851}. Synapse {ECO:0000269|PubMed:25534236}. Note=Detected at GABAergic synapses. {ECO:0000269|PubMed:25534236}.
Interaction partners:
Sequence:
MGSARRALSVVPAVLLILVLPVWAQNDTEPIVLEGKCLVVCDSNPATDSKGSSSSPLGISVRAANSKVAFSAVRSTNHEPSEMSNKTRIIYFDQILVNVGNFFTLESVFVAPRKGIYSFSFHVIKVYQSQTIQVNLMLNGKPVISAFAGDKDVTREAATNGVLLYLDKEDKVYLKLEKGNLLGGWQYSTFSGFLVFPL
Protein: Homeobox protein Hox-C13 (Homeobox protein Hox-3G) (P31276)
Organism: Homo sapiens (Human)
Function: Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Forkhead box protein N1
- Homeobox protein Hox-C10
Sequence:
MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSKAPHLHST
Protein: PBX homeobox 3 (Q5JS98)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQSLVKDPKERGSKGSDIQPTSVVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN
Protein: Sorting nexin-3 (Q3B7E7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle, phagosome {ECO:0000256|ARBA:ARBA00004262}. Early endosome {ECO:0000256|ARBA:ARBA00004412}.
Interaction partners:
- Vacuolar protein sorting-associated protein 35
- Vacuolar protein sorting-associated protein 26A
- Vacuolar protein sorting-associated protein 29
- Vacuolar protein sorting-associated protein 26B
- Vacuolar protein sorting-associated protein 26B-like
- Sorting nexin 2.
- Sorting nexin
- Sorting nexin
- Protein wntless homolog
- Sorting nexin-27
Sequence:
MAEAIADTRRLYTKPQNLNDAYGPPSNFLEIDVTNPETVGVGRNRFTTYEIKLKTNLPIFKLKESRVRRRYSDFEWLRGELERESKVVVPPLPGKALFRQLPFRGDDGIFDDSFIEERRQGLEQFLNKVAGHPLAQNERCLHMFLQDESVDKNYTPSKIRQA
Protein: LH1 alpha polypeptide (D2Z0P2)
Organism: Thermochromatium tepidum (Chromatium tepidum)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004401}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
Interaction partners:
Sequence:
MFTMNANLYKIWLILDPRRVLVSIVAFQIVLGLLIHMIVLSTDLNWLDDNIPVSYQALGKK
Protein: Acetylcholinesterase (AChE) (EC 3.1.1.7) (P23795)
Organism: Bos taurus (Bovine)
Function: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Subcellular location: Synapse. Secreted. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform H]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Interaction partners:
- Glycerophosphocholine phosphodiesterase GPCPD1
- Ethanolamine kinase
- Phosphoethanolamine/phosphocholine phosphatase
- Amyloid-beta precursor protein
- Solute carrier family 18 member 3
- Collagen like tail subunit of asymmetric acetylcholinesterase.
- Collagen like tail subunit of asymmetric acetylcholinesterase
- receptor protein-tyrosine kinase
- Beta-secretase 1
- Albumin
Sequence:
MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVSAFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELVACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYEIEFIFGLPLEPSLNYTIEERTFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQYVSLNLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
Protein: Zinc finger BED domain-containing protein 2 (Q9BTP6)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator which has intrinsic repressor activity and which competes with the transcriptional activator IRF1 for binding to the 5'-[CA]GAA[AC]C[CT]-3' consensus sequence in gene promoters. May thereby play a role in keratinocyte differentiation.
Subcellular location: Nucleus {ECO:0000305|PubMed:32385160}.
Interaction partners:
Sequence:
MMRREDEEEEGTMMKAKGDLEMKEEEEISETGELVGPFVSAMPTPMPHNKGTRFSEAWEYFHLAPARAGHHPNQYATCRLCGRQVSRGPGVNVGTTALWKHLKSMHREELEKSGHGQAGQRQDPRPHGPQLPTGIEGNWGRLLEQVGTMALWASQREKEVLRRERAVEWRERAVEKRERALEEVERAILEMKWKVRAEKEACQREKELPAAVHPFHFV
Protein: Protein SAR DEFICIENT 4 (Ornithine cyclodeaminase-like protein) (AtOCD) (Q9FLY0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the biosynthesis of pipecolate (Pip), a metabolite that orchestrates defense amplification, positive regulation of salicylic acid (SA) biosynthesis, and priming to guarantee effective local resistance induction and the establishment of systemic acquired resistance (SAR). Converts delta-(1)-piperideine-2-carboxylate (P2C) to Pip. Mediates reduction of P2C and biosynthesis of Pip in systemic tissue and contributes to SAR establishment. Does not possess ornithine cyclodeaminase activity in vitro.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:24237637}.
Interaction partners:
- Aminotransferase ALD1, chloroplastic
- Probable flavin-containing monooxygenase 1
- Proline iminopeptidase
- Probable aminotransferase ACS10
- Probable aminotransferase ACS12
- Arginase 1, mitochondrial
- Arginase 2, chloroplastic/mitochondrial
- UDP-glycosyltransferase 76B1
- Calmodulin-binding protein 60 G
- Receptor like protein 26
Sequence:
MAALPVFIPAESFPSILSHETLINHFRTNLPKHSSTITSPVRQNYTVSSPSSLLLMPSWSSSSSLPYMGVKLVTYFPHNSSQNLPGIHGSYTLFSSTTGQTLATMDGTVLTLYRTSSVSGLGSKILARDDSQVLIMVGSGALAPHLIKSHLAAKPSLRRVIIWNRTPQRAQELAETLSKDPQHKEISFDSHDSLDQIIPLGDIISCATNSTVPLVKGEFLKPGTHLDLVGSFSHEMKECDDNAIQRGSVFVDNDTAMIEAGELAGAFERGVIKREDICGNLVELIKGDKEGRKSSTDITVFKSVGSGTVDLLTAQLVHETYLSRC
Protein: Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa) (Q9BTP7)
Organism: Homo sapiens (Human)
Function: Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:17289582}.
Interaction partners:
- Fanconi anemia group M protein
- Fanconi anemia group B protein
- Fanconi anemia group G protein
- Fanconi anemia core complex-associated protein 100
- Fanconi anemia group A protein
- Centromere protein X
- Centromere protein S
- E3 ubiquitin-protein ligase FANCL
- Fanconi anemia group C protein
- FA core complex associated protein 20
Sequence:
MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR
Protein: Trafficking protein particle complex subunit 3 (A0A087WYS5)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus, cis-Golgi network {ECO:0000256|ARBA:ARBA00004222}.
Interaction partners:
Sequence:
MSRQANRGTESKKMVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE
Protein: Vacuole membrane protein HFL1 (Has fused lysosomes protein 1) (P36142)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:34088313}; Multi-pass membrane protein {ECO:0000269|PubMed:16847258}.
Interaction partners:
- Autophagy-related protein 8
- SUMO-conjugating enzyme UBC9
Sequence:
MENKLLCWWLYWPCVYSSIIATIISFYTITRHLLNYRKPYEQRLSIRILLLVPIFSVSCASGIIKPEAAQFYVDPIREFYEAFVIYTFFTFLTLLLGGERNIITVLSLNHAPTRHPIPLIGKICKPIDLSDPFDFLFVKKGILQYVWFKPFYCFGTLICSAWKLPKFEIFLNVFYNISVTWSLYSLALFWKCLYPELTPYKPWLKFLCVKLIIFASYWQSIIIQGLVVTGKLGTGNQDRTSGYVYKNGLLCIEMVPFAILHAVAFPWNKYTAFSIPYGARMKFIYALKDFLGCGDLIWDFKQTLFAGPLYYNYRNFDPEAMDLLSTRQQSGATMERLKHGLRFTDNGRNSYWVAYGSIDNNLVPESIEESWEDDIAGQRTFPEDPNYPVVHDYTMGHRYSRSMNDLRRDVQSRSSMAC
Protein: RIC3 acetylcholine receptor chaperone, isoform J (RIC3 acetylcholine receptor chaperone, isoform R) (E1JGP5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}.
Interaction partners:
Sequence:
MPATATSKPRAPLVEEGMTPKKTALIIVTVIGCIAILWPKVFHPMMFGGVPPSQPNFKDPRAAPGGLRQERPAHLHPESIYQAMRERGRAIPATPTVPILERKTSPSNPPPRIVDGRPGPIPGMRPPMGAGALHQPQQRGSSMGFLMPLYTIGIVVFFGYTLMKIMFKKQVPNDPYGAAPPNPAFRQEVFGSQNHSQVEDLGGSKLGWREHQTRAATATAAAKKPAAKDTEKELYNASVSATEVASSLSASLKSHQQLKEAEQLMEIEKLRQKLESTERAMAQLVAEMNTDQYEAKKNDNEKTREQPLDKQNLSNGHASSTDQNPEQETVAKGARKRRDLSAEQELTVLGMELTASCEGGHKWTGRPPTPVFRAPSEHSKLEDNLPEPQSIYLEGALAHESQILVADSQIKREEVYDSELNGSAEEPAIILSSRMTLSLINLDANQQNGNAGKSAVESPLADDIEIIGHDEQ
Protein: At5g63780 (RING/FYVE/PHD zinc finger superfamily protein) (Q8GUG6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- E3 ubiquitin protein ligase RIE1
- Trihelix transcription factor ASIL1
- At3g10000
- Ubiquitin domain-containing protein 7SL RNA2
- Trihelix transcription factor GTL2
- Trihelix transcription factor GTL1
- Putative RING zinc finger protein
- Putative F-box/FBD/LRR-repeat protein At5g56810
- F-box/kelch-repeat protein At3g13680
- F-box/LRR-repeat protein At3g59210
Sequence:
MGKENQLETTNCGVNDHDCPPVKNEELAAEARYSTDSDSGLPTCRVCHSAESDRRGDTALGFLGITPPVPEARKSNVDGTADDVSKATESELKNSVVKSNGRESGFIELTSPDAEVFICTNDIEMGIQQHQDALLELGCSCKNELALVHYACALKWFLNHGSTVCEICGHPAENIKTADFNKVVIALRDYTAIRERTADGGDQIPVLPVNTDSTIDSDEVAVIRRQRLSEITSWFGPHSLNNNNNNNSSVAAIPDQPLGVVNFDILPMENRATKWAVEGTGILLATGLLTVTLVWLIAPRVGKKTARSGLHILLGGLCALTIVIFFRFVVLTRIRYGPARYWAILFIFWFLVFGIWASRSNASHNSP
Protein: DnaJ homolog subfamily C member 28 (Q9NX36)
Organism: Homo sapiens (Human)
Function: May have a role in protein folding or as a chaperone.
Interaction partners:
- Constitutive coactivator of PPAR-gamma-like protein 2
- M-phase-specific PLK1-interacting protein
Sequence:
MNTMYVMMAQILRSHLIKATVIPNRVKMLPYFGIIRNRMMSTHKSKKKIREYYRLLNVEEGCSADEVRESFHKLAKQYHPDSGSNTADSATFIRIEKAYRKVLSHVIEQTNASQSKGEEEEDVEKFKYKTPQHRHYLSFEGIGFGTPTQREKHYRQFRADRAAEQVMEYQKQKLQSQYFPDSVIVKNIRQSKQQKITQAIERLVEDLIQESMAKGDFDNLSGKGKPLKKFSDCSYIDPMTHNLNRILIDNGYQPEWILKQKEISDTIEQLREAILVSRKKLGNPMTPTEKKQWNHVCEQFQENIRKLNKRINDFNLIVPILTRQKVHFDAQKEIVRAQKIYETLIKTKEVTDRNPNNLDQGEGEKTPEIKKGFLNWMNLWKFIKIRSF
Protein: Vacuolar protein sorting-associated protein 64 (Factor arrest protein 9) (Q03944)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Participates in the control of the reentry into the cell cycle following pheromone treatment. Involved in vacuolar protein sorting.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Interaction partners:
- Factor arrest protein 3
- Factor arrest protein 7
- Factor arrest protein 11
- Factor arrest protein 8
- 2-oxoglutarate dehydrogenase, mitochondrial
- Serine/threonine-protein phosphatase PP2A-like PPG1
- Factor arrest protein 10
- Protein SPT23
- Putative uncharacterized membrane protein YDR199W
Sequence:
MVELEKRRRPPPQLQHSPYVRDQSNSQGMTKTPETSPPKRPMGRARSNSRSSGSRSNVDIDQYTIPPGLDLLPTASSPPSVHQVSQQQQLSPILANKIRSPFENQSQDQNDNSIDPTPAGQVTIPVEAVSPPALDELSKFQNGSTETLFRTGSPRKKHTHIIILKSLNATFETKFLVVPFKPDGLKLGRPVTNSVNKNNSGSKRDLFSQQVRPDNGNFDSRVLSRNHACLSCDPTSGKIYIRDLKSSNGTFVNGVKIRQNDVELKVGDTVDLGTDIDSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQDHTNKNNGNSTNINGIKIDRGHHNQHIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSGIFINNSAGTSINLINMIKTLTTELSLEKQELEKLHSMQNFMQNYTINLDFINKHMIDMNEKHLLKLSTALQKTLSENNDALLKESEDQLKEIKQQNNKVKSACSLKEKQNHEKLQELESELRELNLQIEEERGKNLVLTQSNFNGGINNDNNAKVKQNDSREEKKDTEDTLISTEELGVVEGKRTRVSKGMLFGVVAISFGLVATAVKQLPQ
Protein: Hexosyltransferase (EC 2.4.1.-) (F5GUA1)
Organism: Caenorhabditis elegans
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU363063}.
Interaction partners:
Sequence:
MRESVRKTWGVFRMIDGVEVMPIFIVGRVENMEIMRRIDVESEKYKDILAISDIDSYRNNTLKLFGAIDYAANPNQCSSPDFTFLVDDDYLVHIPNLVKFAKTKQKEELVYEGFVFDTSPFRLKIHKHSISLNEYPFSRYPPYVSAGAVFLTSETIARFRNSIRKLKMFPFDDVFTGILAKTVNVAATHNENFIFWCRRVSQKEWDDGVIAVHGYARKDLEYEYSQLNGFE
Protein: Nitrate reductase [NADH] 1 (NR1) (EC 1.7.1.1) (P11832)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
Interaction partners:
- Ferredoxin--nitrite reductase, chloroplastic
- Nitrate reductase 2
- High-affinity nitrate transporter 2.1
- High-affinity nitrate transporter 2.2
- High affinity nitrate transporter 2.3
- High affinity nitrate transporter 2.5
- High affinity nitrate transporter 2.4
- High affinity nitrate transporter 2.6
- High affinity nitrate transporter 2.7
- F17F8.22
Sequence:
MATSVDNRHYPTMNGVAHAFKPPLVPSPRSFDRHRHQNQTLDVILTETKIVKETEVITTVVDSYDDSSSDDEDESHNRNVPYYKELVKKSNSDLEPSILDPRDESTADSWIQRNSSMLRLTGKHPFNAEAPLPRLMHHGFITPVPLHYVRNHGAVPKANWSDWSIEITGLVKRPAKFTMEELISEFPSREFPVTLVCAGNRRKEQNMVKQTIGFNWGSAGVSTSLWKGIPLSEILRRCGIYSRRGGALNVCFEGAEDLPGGGGSKYGTSIKKEMAMDPARDIILAYMQNGELLTPDHGFPVRVIVPGFIGGRMVKWLKRIIVTPQESDSYYHYKDNRVLPSLVDAELANSEAWWYKPEYIINELNINSVITTPGHAEILPINAFTTQKPYTLKGYAYSGGGKKVTRVEVTLDGGDTWSVCELDHQEKPNKYGKFWCWCFWSLDVEVLDLLSAKDVAVRAWDESFNTQPDKLIWNLMGMMNNCWFRIRTNVCKPHRGEIGIVFEHPTRPGNQSGGWMAKERQLEISSESNNTLKKSVSSPFMNTASKMYSISEVRKHNTADSAWIIVHGHIYDCTRFLKDHPGGTDSILINAGTDCTEEFEAIHSDKAKKLLEDYRIGELITTGYDSSPNVSVHGASNFGPLLAPIKELTPQKNIALVNPREKIPVRLIEKTSISHDVRKFRFALPSEDQQLGLPVGKHVFVCANINDKLCLRAYTPTSAIDAVGHIDLVVKVYFKDVHPRFPNGGLMSQHLDSLPIGSMIDIKGPLGHIEYKGKGNFLVSGKPKFAKKLAMLAGGTGITPIYQIIQSILSDPEDETEMYVVYANRTEDDILVREELEGWASKHKERLKIWYVVEIAKEGWSYSTGFITEAVLREHIPEGLEGESLALACGPPPMIQFALQPNLEKMGYNVKEDLLIF
Protein: Heat shock protein (Eurofung) (Q5B4B4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Ribosome associated DnaJ chaperone Zuotin, putative
- DnaJ domain protein Psi, putative
- Heat shock protein
- Protein mitochondrial targeting protein
- UBA/TS-N domain protein
- Puatative oxidoreductase
- Heat shock protein 90
- DnaJ domain protein
- Heat shock protein
- HSF-type DNA-binding domain-containing protein
Sequence:
MSDEINGTGERFAIGISFGNSSSSIARINPEGKAEVIANEEGDRQIPSILSYIGGEQYHGTQAKAQLIRNPSNTVAYFRDYLGKDFKSIDPTPCHNSAHPIQSDSTVAFSIRDTESETPNTVTVSEITTRHLLRLKQSASDFLGREVNAAVVTVPTDFNDAQREALTAAAKAAGLDILQLIHEPVAAALAYDARPEAVVTDKLIVVADLGGTRSDVAVIACRGGMYTILATAHDYELGGSTLDQIIIDHFAKEFIKKHKTDPRENARGLAKLKMEGEATRKALSLGTNATLSIESLTDGIDYGSTINRTRYELLSSKVFAQFTGLIEQVIKKAELDVLDIDEVIFSGGVSHTPKIAQLARNLFPEKTRILAPSTLASAINPSELSARGAAIQASLIQEFETEDIEQSIHPMVTATPHLSKAIGVEFTSGDAVEFLPLLNTETALPARRVAQYSVPAEGGDVLIRVCEGSREIKVTKPEPKPKEEKSKAEDDEDDSDFDSDEEEEDIREIVWKTEQPIAELAVKGVKAKGKVELMIHINADLGLQITAREVGGQSAVRGAVESP
Protein: Equilibrative nucleotide transporter 4 (AtENT4) (Nucleoside transporter ENT4) (Q9M0Y2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Nucleoside transporter that can mediate uptake of adenosine, uridine, guanosine or cytidine when expressed in a heterologous system (yeast).
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000305}. Note=Plasma membrane.
Interaction partners:
- Putative defensin-like protein 101
- Putative defensin-like protein 135
- Putative defensin-like protein 62
- Defensin-like protein 90
- Putative F-box protein At4g05475
- FCS-Like Zinc finger 7
- Allantoinase
- Putative F-box/LRR-repeat protein 21
- F-box/LRR protein
- Putative F-box/LRR-repeat protein 23
Sequence:
MADGYENHAPENLQGKYQAMVVCCILGIGSLFSWNSMLTIADYYYQVFPDYHPSRVFTLIYQPIALGTIMILAYRESKISTRKRILTGYILFTISTFLLIVLDLTTKGHGGIGHYIVLCTIVASFGLADATVKGGLVGDLSLMCPELIQSYMAGSGMAGALTSVLRLITKAAFEKSNNSLRKGAMIFLAISTFIELLCVILYAYVFPKLPIVKYYRRKAASEGSKTVVADLAAAGIQNLSDLSDDDSKNQMLRKKELLLQNIDHAVNLFLIYVLTLSIFPGFLYENTGQHGLGDWYALILVATYNFWDLFGRYAPLVKWLKLENRKALTIAVLTRYFLVPAFYFTAKYGDKGWMIMLVSILGLTTGHLTVCIMTIAPNGYKGPEKNALGNLLVVFILGGAVVGISLGWLWLIGKKYAF