wanglab/gogpt-training-data huggingface dataset:
Protein: Protein PDC2 (P32896)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential for the synthesis of pyruvate decarboxylase. May be important for a high basal level of PDC gene expression or play a positive role in the autoregulation control of PDC1 and PDC5.
Interaction partners:
- Thiamine metabolism regulatory protein THI3
- Thiamine biosynthesis regulatory protein
- Pyruvate decarboxylase isozyme 1
- Pyruvate decarboxylase isozyme 2
- Uncharacterized protein YLR177W
- Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20
- Thiamine thiazole synthase
- Thiamine transporter
Sequence:
MLSIQQRYNICLMAERHPKWTQLELAKWAYETFQLPKIPSQGTISRLLARKSTYMNCKEHEKDANRLRKPNNLLVRKILQEWISQSLWNGIPITSPIIQDTAQAVWHRIPAEHREGNGSFSYKWISNFLSKMDVNISVLDEELPKTPKVWTFEERDVLKAYFSKIPPKDLFTLDEAFLSYNLPLDYAQYEASSIQRRIEVATVMLCSNLDGSEKLKPVVVGKYDSYKSFRNYFPNEPNDPVSQSMLGTKMAKKFDISYHSNRKAWLTSNLFHNWLVRWDKRLVAVNRKIWIVLDDSCCHRIINLRLQNIKLVYTSSNSKFLPFNWGVWDEFKTRYRIQQYQALIDLQNRISKNIQNKNKSERNECIPNGKKCLISFEQSQLTMSNAFKFIKKAWDDIPVDAIKANWKSSGLLPPEMIHLNENVSMAFKKNEVLESVLNRLCDEYYCVKKWEYEMLLDLNIENKNTNFLSTEELVESAIVEPCEPDFDTAPKGNEVHDDNFDVSVFANEDDNNQNHLSMSQASHNPDYNSNHSNNAIENTNNRGSNNNNNNNGSSNNINDNDSSVKYLQQNTVDNSTKTGNPGQPNISSMESQRNSSTTDLVVDGNYDVNFNGLLNDPYNTMKQPGPLDYNVSTLIDKPNLFLSPDLDLSTVGVDMQLPSSEYFSEVFSSAIRNNEKAASDQNKSTDELPSSTAMANSNSITTALLESRNQAQPFDVPHMNGLLSDTSKSGHSVNSSNAISQNSLNNFQHNSASVAEASSPSITPSPVAINSTGAPARSIISAPIDSNSSASSPSALEHLEGAVSGMSPSSTTILSNLQTNINIAKSLSTIMKHAESNEISLTKETINELNFNYLTLLKRIKKTRKQLNSESIKINSKNAQDHLETLLSGAAAAAATSANNLDLPTGGSNLPDSNNLHLPGNTGFF
Protein: Ras-related protein M-Ras (EC 3.6.5.2) (Ras-related protein R-Ras3) (P97538)
Organism: Rattus norvegicus (Rat)
Function: Serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Leucine-rich repeat protein SHOC-2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Ral guanine nucleotide dissociation stimulator
- Neurofibromin
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- RAF proto-oncogene serine/threonine-protein kinase
- phosphatidylinositol-4,5-bisphosphate 3-kinase
- SOS Ras/Rho guanine nucleotide exchange factor 2
Sequence:
MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVPEKNQKKKKKTKWRGDRATGTHKLQCVIL
Protein: Ras-related protein Rab-3C (EC 3.6.5.2) (Q96E17)
Organism: Homo sapiens (Human)
Function: Protein transport. Probably involved in vesicular traffic (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Regulating synaptic membrane exocytosis protein 2
- Rab15 effector protein
- RIMS-binding protein 2
- Rabphilin-3A
- Peripheral-type benzodiazepine receptor-associated protein 1
- Regulating synaptic membrane exocytosis protein 1
Sequence:
MRHEAPMQMASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQNTRLKETPPPPQPNCAC
Protein: Calcium/calmodulin-dependent protein kinase II association-domain domain-containing protein (F5GUA9)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSNYERAAPSSHGSSTTKKIANAIADLVIRRSSPSIRRKTEADVHNSNRNRKVSAPANLQHALVPVIDVVVATGALASSSVDNLSASTSSDLGRNLLNKKEQGPPSTIKESSESSQTIDDNDSEKGGGQLKHENTVVRADGATGIVSSSNSSTASKSSSTNLSAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFDGNRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDRNGEAHTRQSQESRVWSKKQGRWVCVHVHRSTQPSTNTTVSEF
Protein: BPTI/Kunitz domain-containing protein (P86733)
Organism: Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone)
Function: Serine protease inhibitor.
Subcellular location: Secreted {ECO:0000269|PubMed:21050442}.
Interaction partners:
Sequence:
LFVGLTSAKYHDVCQLPRDPGPCRAYIPLYYFNSRTCLCEKFVYGGCQGNANRFDTVEDCRRRCGGGDLCSLPRDSGPCEAAIPRWWYNKRTNRCQRFTYGGCEGNANNFKTLDECRFQCRKRSTY
Protein: PA26 p53-induced protein (Sestrin) (Q388Q1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Vacuolar membrane-associated protein Iml1 N-terminal domain-containing protein
- WD repeat protein mio zinc-ribbon like domain-containing protein
- Uncharacterized protein
- WD repeat protein mio zinc-ribbon like domain-containing protein
- WD repeat protein mio zinc-ribbon like domain-containing protein
- Ras-family member, GTP-binding protein, putative
Sequence:
MQPNTMLPEGQDSSEADNHLACPSFAELITSVLGHIGDTYALERKAHQHAAQSEQSAHQNHSLRVLFRVPSEDAVQCDALGPSGAQPATLGFADDMAKQLSALVAECDVGCVPAGLIKCTSRYLQRACMLLRDAENGLKSCQAVSRGSHSGVGHHSSSIGIDVSACDDDGRLAQQCKIRKPTVESVSRSFPLAYSSEDGTSLMSGDYHTGDAVRGERSYAGSLHEAEMAFCCLIGIAFSCPCQSLANCLQLIIADVLGKAICPSGLRGRILKCLSQVDARTIRETQVSELWGMESNANFLYVVEGKLVRLNWDEVLSPRLHEATDVKWYVAPSPTAALPTLGQLLSGRLSRELDALQKSVSTAGTMPRCSLPSSSSTPSLARRRLGTLSKGRTSSCGAIDGELANKEASKEKDATQQALWEALSHCSIASLRSLCSGRRDLLYRIFTDMGELPQYYYVLSACPEFLKAHHSTFIYVFFGNGPLLNSERLMVAFMTACRQKCEYLVCRFGALLMRVGGKEGGVCGTARSWLRDGPPPKLQALQRFIAIATHVPWQISDVDIRTAMSAGWSIHGLMQVSTIVAETLSLCSLVMGLFVPNDLCSFTALPPALAALLSPCVVVGDEHHHNADISFTRYTGVDDIVSEKRIKGSNVGGCTLRSGNFNWQEHGSTLMEQYYPGAASLINDEFDALAGVVRRLNHSDCVGLTSPEYSPAYAFQSLLLYVQNIIGFMSDNYPYNDINKVLRRPAKLIAQTCTMHPETLSGAQLRLWMQPAVEGSTSTGDFSSSQVLSGDTRRRMTAERRAEDQKQELIESLNRHRAPFTLSLPGDSTEHCGRPEDDVVEEALRLHEEWLVLVLLLCTMKARKEGLMTLLLYPMWKILNNM
Protein: ATP-binding cassette sub-family D member 1 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy protein) (ALDP) (P33897)
Organism: Homo sapiens (Human)
Function: ATP-dependent transporter of the ATP-binding cassette (ABC) family involved in the transport of very long chain fatty acid (VLCFA)-CoA from the cytosol to the peroxisome lumen. Coupled to the ATP-dependent transporter activity has also a fatty acyl-CoA thioesterase activity (ACOT) and hydrolyzes VLCFA-CoA into VLCFA prior their ATP-dependent transport into peroxisomes, the ACOT activity is essential during this transport process. Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation. Involved in several processes; namely, controls the active myelination phase by negatively regulating the microsomal fatty acid elongation activity and may also play a role in axon and myelin maintenance. Controls also the cellular response to oxidative stress by regulating mitochondrial functions such as mitochondrial oxidative phosphorylation and depolarization. And finally controls the inflammatory response by positively regulating peroxisomal beta-oxidation of VLCFAs (By similarity).
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:10777694, ECO:0000269|PubMed:16946495, ECO:0000269|PubMed:17609205, ECO:0000269|PubMed:18757502, ECO:0000269|PubMed:29397936}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:16946495}; Multi-pass membrane protein. Lysosome membrane {ECO:0000269|PubMed:16946495}; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16946495}; Multi-pass membrane protein.
Interaction partners:
- ATP-binding cassette sub-family D member 3
- ATP-binding cassette sub-family D member 2
- Peroxisomal biogenesis factor 19
- Long-chain fatty acid transport protein 2
- Peroxisomal biogenesis factor 3
- Long-chain-fatty-acid--CoA ligase ACSBG1
- Spastin
- Peroxisomal membrane protein PEX13
- B-cell receptor-associated protein 31
- Peroxisomal membrane protein 11B
Sequence:
MPVLSRPRPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAPAGEPTQEASGVAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST
Protein: CTP synthase (EC 6.3.4.2) (UTP--ammonia ligase) (X2JCY2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTFSPYEHGEVYVLDDGAEVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPHITDAIQEWVERVAQTPVQGSSKPQVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCLAHVSLVPLPKATGEPKTKPTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVICIHDLNSIYHVPLLMEQNGVIEYLNERLQLNIDMSKRTKCLQQWRDLARRTETVRREVCIAVVGKYTKFTDSYASVVKALQHAALAVNRKLELVFIESCLLEEETLHSEPSKYHKEWQKLCDSHGILVPGGFGSRGMEGKIRACQWARENQKPLLGICLGLQAAVIEFARNKLGLKDANTTEIDPNTANALVIDMPEHHTGQLGGTMRLGKRITVFSDGPSVIRQLYGNPKSVQERHRHRYEVNPKYVHLLEEQGMRFVGTDVDKTRMEIIELSGHPYFVATQYHPEYLSRPLKPSPPFLGLILASVDRLNQYIQRGCRLSPRQLSDASSDEEDSVVGLAGATKSLSSLKIPITPTNGISKSCNGSISTSDSEGACGGVDPTNGHK
Protein: CLIP-associated protein (AtCLASP) (Q8RWY6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cortical microtubule plus-end tracking protein required for cell morphogenesis and cell division. Promotes the stabilization of dynamic microtubules during mitosis. Regulates microtubule-cortex attachment, thereby contributing to self-organization of cortical microtubules and subsequent cell shape.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17873093, ECO:0000269|PubMed:18042620}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17873093}. Cytoplasm, cytoskeleton, phragmoplast {ECO:0000269|PubMed:17873093}. Cytoplasm, cell cortex {ECO:0000269|PubMed:21847104}. Note=Associates with cortical microtubules. {ECO:0000269|PubMed:18042620}.
Interaction partners:
- Sorting nexin 1
- Microtubule-associated protein RP/EB family member 1B
- Microtubule-associated protein RP/EB family member 1A
- Microtubule-associated protein RP/EB family member 1C
- Protein CELLULOSE SYNTHASE INTERACTIVE 1
- Ras-related protein RABA5c
- Amidophosphoribosyltransferase 1, chloroplastic
- 187-kDa microtubule-associated protein AIR9
- 65-kDa microtubule-associated protein 1
- Tubulin beta-6 chain
Sequence:
MEEALEMARAKDTKERMAAVERLHQLLEASRKSLSPAEVTSLVDSCLDLLKDSNFRVSQGALQALASAAVLAGEHLKLHLNALVPAVVERLGDSKQPVRDAARRLLTTLMEVSSPTIIVERAGSYAWMHKSWRVREEFARTVTSAIGLFASTELPLQRVILAPILQMLNDPNQAVREAAILCIEEMYMQGGSQFREELQRHHLPSYMVKDINARLERIEPQLRSTDGRSAHHVVNEVKASSVNPKKSSPRAKAPTRENSLFGGDADITEKPIEPIKVYSEKELIREFEKIAATLVPEKDWSMRISAMRRVEGLVAGGATDYSCFRGLLKQLVGPLSTQLADRRSTIVKQACHLLCLLSKELLGDFEACAETFIPVLFKLVVITVLVIAESADNCIKTMLRNCKAARVLPRIAESAKHDRNAILRARCCEYALLTLEHWPDAPEIQRSVDLYEDLIRCCVADAMSEVRATARMCYRMFAKTWPDRSRRLFSSFDPVIQRLINEEDGGIHRRHASPSVRERHSQPSFSQTSAPSNLPGYGTSAIVAMDRSSNLSSGGSLSSGLLLSQSKDVNKGSERSLESVLQSSKQKVSAIESMLRGLHISDRQNPAALRSSSLDLGVDPPSSRDPPFHAVAPASNSHTSSAAAESTHSINKGSNRNGGLGLSDIITQIQASKDSGRSSYRGNLLSESHPTFSSLTAKRGSERNERSSLEESNDAREVRRFMAGHFDRQQMDTAYRDLTFRESNASHVPNFQRPLLRKNVGGRMSAGRRRSFDDSQLQIGDISNFVDGPASLNEALNDGLNSSSDWCARVAAFNFLQTLLQQGPKGAQEVIQSFEKVMKLFLRHLDDPHHKVAQAALSTLADLIPSCRKPFESYMERVLPHVFSRLIDPKEVVRQPCSSTLEIVSKTYSVDSLLPALLRSLDEQRSPKAKLAVIEFAINSFNRYAGNPEISGNSGILKLWLAKLTPLTRDKNTKLKEASITCIISVYNHYDSAGLLNYILSLSVEEQNSLRRALKQYTPRIEVDLLNYMQSKKEKQRIKSYDPSDAIGTSSEEGYAGASKKNIFLGRYSGGSIDSDSGRKWSSSQEPTMITGGVGQNVSSGTQEKLYQNVRTGISSASDLLNPKDSDYTFASAGQNSISRTSPNGSSENIEILDDLSPPHLEKNGLNLTSVDSLEGRHENEVSRELDLGHYMLTSIKVNTTPESGPSIPQILHMINGSDGSPSSSKKSGLQQLIEASVANEESVWTKYFNQILTVVLEVLDDEDFSIKELALSLISEMLKSQKDAMEDSVEIVIEKLLHVSKDTVPKVSTEAEQCLTTVLSQYDPFRCLSVIVPLLVTEDEKTLVACINCLTKLVGRLSQEELMDQLSSFLPAVFEAFGSQSADVRKTVVFCLVDIYIMLGKAFLPYLEGLNSTQVRLVTIYANRISQARNGAPIDADT
Protein: Na(+)-translocating NADH-quinone reductase subunit F (Na(+)-NQR subunit F) (Na(+)-translocating NQR subunit F) (EC 7.2.1.1) (NQR complex subunit F) (NQR-1 subunit F) (A5F5Y4)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00430, ECO:0000305}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00430}.
Interaction partners:
Sequence:
MSTIIFGVVMFTLIILALVLVILFAKSKLVPTGDITISINGDPEKAIVTQPGGKLLTALAGAGVFVSSACGGGGSCGQCRVKIKSGGGDILPTELDHISKGEAREGERLACQVAVKADMDLELPEEIFGVKKWECTVISNDNKATFIKELKLAIPDGESVPFRAGGYIQIEAPAHHVKYADFDVPEKYRGDWDKFNLFRYESKVDEPIIRAYSMANYPEEFGIIMLNVRIATPPPNNPNVPPGQMSSYIWSLKAGDKCTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVEDFDGLAAENDNFVWHCALSDPQPEDNWTGYTGFIHNVLYENYLKDHEAPEDCEYYMCGPPMMNAAVINMLKNLGVEEENILLDDFGG
Protein: Endoplasmic reticulum transmembrane helix translocase (EC 7.4.2.-) (Complexed with DOR1 protein 1) (Endoplasmic reticulum P5A-ATPase) (Sensitivity to the P.farinosa killer toxin protein 1) (P39986)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12058017, ECO:0000269|PubMed:22745129, ECO:0000269|PubMed:24392018, ECO:0000269|PubMed:30785834}; Multi-pass membrane protein {ECO:0000269|PubMed:32973005}. Note=Localizes to endoplasmic reticulum regions devoid of phosphatidylinositol 4-phosphate (PI4P) hydrolytic machinery. {ECO:0000269|PubMed:30785834}.
Interaction partners:
- Calcium channel YVC1
- Calcium-transporting ATPase 1
- Retrograde regulation protein 3
- Retrograde regulation protein 1
- GPI ethanolamine phosphate transferase 2
- Calcium-channel protein CCH1
- Phosphoglycerate kinase
Sequence:
MTKKSFVSSPIVRDSTLLVPKSLIAKPYVLPFFPLYATFAQLYFQQYDRYIKGPEWTFVYLGTLVSLNILVMLMPAWNVKIKAKFNYSTTKNVNEATHILIYTTPNNGSDGIVEIQRVTEAGSLQTFFQFQKKRFLWHENEQVFSSPKFLVDESPKIGDFQKCKGHSGDLTHLKRLYGENSFDIPIPTFMELFKEHAVAPLFVFQVFCVALWLLDEFWYYSLFNLFMIISMEAAAVFQRLTALKEFRTMGIKPYTINVFRNKKWVALQTNELLPMDLVSITRTAEESAIPCDLILLDGSAIVNEAMLSGESTPLLKESIKLRPSEDNLQLDGVDKIAVLHGGTKALQVTPPEHKSDIPPPPDGGALAIVTKTGFETSQGSLVRVMIYSAERVSVDNKEALMFILFLLIFAVIASWYVWVEGTKMGRIQSKLILDCILIITSVVPPELPMELTMAVNSSLAALAKFYVYCTEPFRIPFAGRIDVCCFDKTGTLTGEDLVFEGLAGISADSENIRHLYSAAEAPESTILVIGAAHALVKLEDGDIVGDPMEKATLKAVGWAVERKNSNYREGTGKLDIIRRFQFSSALKRSASIASHNDALFAAVKGAPETIRERLSDIPKNYDEIYKSFTRSGSRVLALASKSLPKMSQSKIDDLNRDDVESELTFNGFLIFHCPLKDDAIETIKMLNESSHRSIMITGDNPLTAVHVAKEVGIVFGETLILDRAGKSDDNQLLFRDVEETVSIPFDPSKDTFDHSKLFDRYDIAVTGYALNALEGHSQLRDLLRHTWVYARVSPSQKEFLLNTLKDMGYQTLMCGDGTNDVGALKQAHVGIALLNGTEEGLKKLGEQRRLEGMKMMYIKQTEFMARWNQPQPPVPEPIAHLFPPGPKNPHYLKALESKGTVITPEIRKAVEEANSKPVEVIKPNGLSEKKPADLASLLLNSAGDAQGDEAPALKLGDASCAAPFTSKLANVSAVTNIIRQGRCALVNTIQMYKILALNCLISAYSLSIIYMAGVKFGDGQATVSGLLLSVCFLSISRGKPLEKLSKQRPQSGIFNVYIMGSILSQFAVHIATLVYITTEIYKLEPREPQVDLEKEFAPSLLNTGIFIIQLVQQVSTFAVNYQGEPFRENIRSNKGMYYGLLGVTGLALASATEFLPELNEAMKFVPMTDDFKIKLTLTLLLDFFGSWGVEHFFKFFFMDDKPSDISVQQVKIASK
Protein: Glycosidase (EC 3.2.-.-) (Q6FWX2)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Cell envelope {ECO:0000256|ARBA:ARBA00004196}. Membrane {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004589}.
Interaction partners:
Sequence:
MLFLISLLSLFANILSVEAAELTAPIYCNATSQCPEEFPCCSQFGQCGTGQYCINNCNPKFSFSIDSCVPMPVCKDSSTKFDDYSSKVLNADTYLNNASAADWTYSGYLVDYPDEDSMILAMPKNSGGSVLSTTRYMWYGKVSARLKSSHLGGVVSSMILFSNVQDEIDIEFIGADLNTVQTNFYWEGTLNYTNSANMTTSNTFENYHDYEIDWHEDYITWSIDGVVGRTLYKNQTYNETTGIYEFPQTPSRIQISIWPGGNATSAPGTIAWAGGAINWDAPDIQDPGYYYMMVQEANITCYDPPANVKKNGTKSYIYTSNKDFTQDSIMISDKDFVLENSAWTGLNLTEGAKAKPSEAKASSKLSSSHNSTSSASSTSFHNSTSSTMHHNSTLTSITSKFSNSTSQSSTKHASTTSKTSERKSTASKTDPSTLQTTTKSSQSSSTSTSTIRNQKDSNTGAITKLNGLCAIIVAILTALLA
Protein: Major facilitator superfamily (MFS) profile domain-containing protein (Q5AYG1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MADGVVAGTRVEAPVTWKTYLMCAFAAFGGIFFGYDSGYINGVMAMDYFIHEFSGKVKAEYEAADNLSGYVISSSNKSLITSILSAGTFFGAIIAGDLADWFGRRTTIISGCGIFMVGVALQTASTTVALLVVGRLIAGFGVGFVSAILILYMSEIAPRKVRGAIVSGYQFCVTVGLMLASCVDYGTENRTDSGSYRIPIGLQLLWAIILAVGLFLLPESPRYYVRKGDVSSAAKVLARVRDQDVESDYVKEELAEIVANNEYEMSLIPQGGYFATWFNCFRGSIWSPNSNLRRTILGTSLQMMQQWTGVNFVFYFGTTFFTNLGTISDPFLISMITTIVNVFSTPISFYTMEKIGRRPLLLWGALGMVICQFIVAIAGVVDGSNNKTVSAQIAFICIYIFFFASTWGPGAWVVIGEIYPLPIRSRGVALSTASNWLWNCIIAVITPYMVDEDKGNLKSKVFFIWGSLCACAFVYTYFLIPETKGLTLEQVDKMMEETTPRTSSKWKPHGTFAAEMGMTEKDVTQTVEDIAKKA
Protein: At1g64880 (Ribosomal protein S5 family protein) (Q6GKU7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS9m
- AT3g18240
- Small ribosomal subunit protein uS2m
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- 50S ribosomal protein L33
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein uL29m
- Ribosomal protein S24/S35
- Large ribosomal subunit protein mL46
- Small ribosomal subunit protein uS14m
Sequence:
MSLRTRASSWPRLLLRRNPRSSFSRQISTLDSSTSTFPRRISGYYSSSFFPVNQTPWISSQRYRFFSSSTMSPSEADRVVRELIAEVEKEKQREREERQRQGLDYKDIDAEDEEDYLGIEPFIEKLKKQNLKDDGELNRREESSDSDSEYDEIDLDEERKKEDIFNKKFQRHKELLQTLTKSETLDEAFRWMNKLDKFEEKHFKLRPEYRVIGELMNRLKVAEGKEKFVLQQKLNRAMRLVEWKEAFDPNNPANYGVIERDNVQGGGEEREERLVADGPKDDNDDDDDEEEFDDMKERDDILLEKLNAIDKKLEIKLSELDHTFGKKGKRLEEEIRELAEDRNALTEKKRQPLYRKGYDVHVIDVKKVCKVTKGGRVERYTALMVCGNYEGIIGYAKAKAETGQSAMQKAYEKCFQNLHYVERHEEHTIAHAIQTSYKKTKLYLWPAPTTTGMKAGRVVKTILLLAGFKNIKSKVIGSRNSYNTVKAVLKALNAVETPKDVQEKFGRTVVEKYLL
Protein: Interferon alpha-8 (IFN-alpha-8) (Interferon alpha-B) (LeIF B) (Interferon alpha-B2) (P32881)
Organism: Homo sapiens (Human)
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Subcellular location: Secreted.
Interaction partners:
- Interferon alpha/beta receptor 1
- Ubiquitin-like protein ISG15
- Interferon alpha/beta receptor 2
- Interferon gamma receptor 1
- Interleukin-2
- Interferon alpha-4
- Interferon alpha-1/13
- Tyrosine-protein kinase JAK2
- Interferon regulatory factor 3
- Tyrosine-protein kinase JAK1
Sequence:
MALTFYLLVALVVLSYKSFSSLGCDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFEFPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLESCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSSCAWEVVRAEIMRSFSLSINLQKRLKSKE
Protein: Calpain-like cysteine peptidase, putative (Q584X4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVVSLSGYSPREVYEVECAKFNCKKNSAICNFLSERPDDFKSISVIDLSKNFVGPKGVLPLLEVVRLCENLELLNLCGQQLDKNAIDALCLVLRSHPTVIHLNLSANPLSMSAGTSLLLLAKDNPLIQHINLTDSFIKPSVLLAINAQLERNREYRGKEADRADIISNVQRNEKLNGGDVRIPLQTSQERGEVLSRPMQPIVQDQNVTSRETDDQAYDSLYPHDLGALLASFTHEVHDVLFDEDPTSYVAKYCSVRRTCFHDADFRADRVPLRRGVRRWDAFAWRRVSKLFPSATLLPEAGEDKTLVFPRECFQAYSWVFTCVEAVFKDAAILRDTLFTSYDVDHGVYGIRVYVDGRWRYVIVDDYLPVNEKNELMFTKPVDNKYFWPCILEKALAKMYGGYLALDIEFILESVPRALSMTPEATTPTNTPLLASNGFPNTVECRDDDVRRTSCAKTLQDLSGGVGITRFLRTAEFQKDEWWASMLDMSRSGAIMVGITDFENALPGIETAHAYRITHVQQVGGIKLVMLSSQWSPQQWKGDWSDDSCLWQSHRDVSMTLRKKRLAGDHFGFWMSYNDFLSVFIQVHICHVFNGFTQHVVECEWGRDTAGGPCFDHHWHLNPHFKLRLSENTLFFINLSLPDTRFAPTCVKAMGMHILNSPRYPVCYLHNTQDCVVATDYVETDSISVEGNFTKEGVYWIVPSADLTGVMSRFILRMFVSSPFVFSSEVIGNHWNTLKFSDIIECSGEFCAGDDNAQVLIRFLTNDKIREEVSVGPIVVKVATPEDKNLAIGLFLVHSSFAGSKASRTLGVVDKGDIVASSPYAVTDRAYIMADVCDNDVYTLITCISPTGSRAEIEYTLWSAIPSPQHTILPVWGRKSVTVSWPEGSGSFYGVKNNPQIEICPERDFDTFVIKMNLVECNVTDPAIVLFVLQNAGNKGDGIKGKIPANQVLKRSQYVRHHFVQCELQLLEPTDSLLVIPCLQPTGSKGACAITVSTETSDFSVRVLSSV
Protein: AF10 (Alhambra, isoform A) (LP22910p1) (Q9VI63)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MCERNNNKQVTSSNKIPSSFNAKLELDSSKDDTIHSTSLNKKLVKIKKFKLDDMKEMVGGCCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSRVRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKTIPPYKPIQHDTSSDSCSSPEKEIDSTMNSATTSATIIKITSSSGSAGGSSNVLNASSSAGISAGSSSGSGVSSSAKQRKSNASSKSSSSSSSSSSSSTGGAPNPSSSSVHSGSASNMTGGGSVLPGSSNIGNISNSLNNNLPGGSSSTSSAGNVPGGSGGIISASSGGATQSTSSQSSTAPGTTKSSASSSSSSSNSYKEKHSKSLSKSTSSKDKDGKDSSTNSANNNFTNSSASSTSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSSINTQPSSSTSTATAGSGGTGTHVSSSAASGLNSAPSTTNEHSNHAHTLSTNGTGAGSAAGKLQSVSNLSNSSSGFGSDLRSVSTSSSSTVNDSTGGFGSNSNSERENLSGAGSSASNMPGTIAPGTGGVSSSAATNLSTNKGGSSSSTANSLTSTSTSSGSSSNSSSKKRKADSAKSTSSISTSGSALEDNNSLISRYDIKDVQVALTPLTDFEKEIEKSSKRQRTELSPPTHQTSATAEVNAPLASSTSASIAVTASATAASAPPATGTTTLGSSISGNAGSTSSGNSSGVSATGGAQSAVGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQASTASSSSAPSLYVSVPLSTANVPGINLPTSSTSSSTTSESHSASSRSSGAQSQHQQQLSNALVGPPMGGSAGAFHGGTTSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISASGFPLPSGNLTATTTESGNLKISYEKQTTRVQQLQEQEAPPARRSRTLDLSTASASSSSPSAVPATTSPLVVLSNQLPLNSVAASSSTGGLKFTYESQTQMDVPMMPVSAIKDSPPSSPGSEIGSAMHSATTAPGSLTGASTAATAQPGNVRKRGRKAKDATIAAAAAAAAAAAALSNSQQDLKDVRILQNGASNTPGNPAGSTPTPPATPASSNAVSSASSIITHTAAHMLGNQINPNSSVAQKLSEQLHMEVQDHSIYTPDSMNSQYAGVPFPGKQRNSTAVPSNATPAQNPLQSMFSGGGMNGNMPIPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLNCLHQLQSENLRLEEHVTSLIARRDHLLAVNARLQIPLSTIASNTKAEAHGK
Protein: Methyl-CpG binding domain protein 2 (D4A986)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Histone deacetylase 1
- Histone deacetylase 2
- Histone deacetylase 1
- Histone-binding protein RBBP7
- Chromodomain-helicase-DNA-binding protein 4
- GATA zinc finger domain containing 2B
Sequence:
MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGAGGCGVGSSGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPNNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCKAFIVTDDDIRKQEERVQQVRKKLEEALMADILSRAVDTEEVDIDMDSGDEE