wanglab/gogpt-training-data huggingface dataset:
Protein: Small polypeptide DEVIL 5 (Small polypeptide ROTUNDIFOLIA like 15) (Small polypeptide ROT-FOUR-LIKE 15) (Q6X5T8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, including leaves shape, pedicule elongation, inflorescence organization and fruit maturation, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Small polypeptide DEVIL 2
- Small polypeptide DEVIL 17
- Small polypeptide DEVIL 14
- Small polypeptide DEVIL 15
- Small polypeptide DEVIL 20
- Small polypeptide DEVIL 23
- Small polypeptide DEVIL 13
- Small polypeptide DEVIL 8
- Small polypeptide DEVIL 1
- Small polypeptide DEVIL 16
Sequence:
MKTTGSSVGGTKRKMWSRGVGGVVREQKAKLYIIRRCVVMLLCWHD
Protein: Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322) (Q9JI59)
Organism: Mus musculus (Mouse)
Function: Junctional adhesion protein that mediates heterotypic cell-cell interactions with its cognate receptor JAM3 to regulate different cellular processes. Plays a role in homing and mobilization of hematopoietic stem and progenitor cells within the bone marrow. At the surface of bone marrow stromal cells, it contributes to the retention of the hematopoietic stem and progenitor cells expressing JAM3. Plays a central role in leukocytes extravasation by facilitating not only transmigration but also tethering and rolling of leukocytes along the endothelium. Tethering and rolling of leukocytes are dependent on the binding by JAM2 of the integrin alpha-4/beta-1. Plays a role in spermatogenesis where JAM2 and JAM3, which are respectively expressed by Sertoli and germ cells, mediate an interaction between both cell types and play an essential role in the anchorage of germ cells onto Sertoli cells and the assembly of cell polarity complexes during spermatid differentiation (Probable). Also functions as an inhibitory somatodendritic cue that prevents the myelination of non-axonal parts of neurons. During myogenesis, it is involved in myocyte fusion (By similarity). May also play a role in angiogenesis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11036763, ECO:0000269|PubMed:25817991}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P57087}. Cell junction {ECO:0000269|PubMed:16093349, ECO:0000269|PubMed:25817991}. Cell junction, tight junction {ECO:0000269|PubMed:11036763, ECO:0000269|PubMed:15372036}. Note=Localized at tight junctions of both epithelial, endothelial cells and Sertoli cells (PubMed:11036763). Specifically localized within the somatodendritic compartment of neurons and excluded from the axon (PubMed:27499083). {ECO:0000269|PubMed:11036763, ECO:0000269|PubMed:27499083}.
Interaction partners:
- Junctional adhesion molecule C
- Tight junction protein 1
- Junctional adhesion molecule A
- Integrin beta-1
- Integrin alpha-4
- Partitioning defective 3 homolog
- Golgi reassembly-stacking protein 2
- Predicted gene, 49948
- Immunoglobulin superfamily member 5
- Occludin
Sequence:
MARSPQGLLMLLLLHYLIVALDYHKANGFSASKDHRQEVTVIEFQEAILACKTPKKTTSSRLEWKKVGQGVSLVYYQQALQGDFKDRAEMIDFNIRIKNVTRSDAGEYRCEVSAPTEQGQNLQEDKVMLEVLVAPAVPACEVPTSVMTGSVVELRCQDKEGNPAPEYIWFKDGTSLLGNPKGGTHNNSSYTMNTKSGILQFNMISKMDSGEYYCEARNSVGHRRCPGKRMQVDVLNISGIIATVVVVAFVISVCGLGTCYAQRKGYFSKETSFQKGSPASKVTTMSENDFKHTKSFII
Protein: ABC transporter B family member 5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5) (ATP-dependent translocase ABCB1) (F1R7A8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKDGPPEESTDPPPYSHEAIPEGFVNLAYSQDEKPHEDKPEEPPSDSKHKGKKGKNSKDNKEPMKSVGFFQLFRYATCPEVFLMLIGLLCAAAHGVALPLMCVVFGQMTDSFVQSGQTYNLTGFNGNFTSNFTFTLNNTSTCLAGSPEIGIEPKMTKQAYFFIGIGGAVLVLGTFQVMLFLLTAAKQTKRIRQKYFHAILHQQMSWFDTHPIGELNIRLTDDINTINDGLGDKIAVFVQFFCSFISGLVIGFVFGWKLTLVILAVSPLLAGSAAVWSKILASLTSKELTAYAKAGAVAEEILVAIRTVVAFNGQKKAVEKYEKNLVEAKDFGVKKAISTNVSMGLTQFIVFATYALAFWYGTKLSVDEPENYTIGRVLTVFFSVMIGTFSLGQGAPNLEAIAKARGAAYEVYKTIDMPRPIDSSSKEGHKPDRVRGDIEFKNINFNYPSRKDVTILQGMSLKVPHGKTIALVGASGCGKSTTIQLLQRFYDPDSGEVTLDGHDIRSLNVRWLRENMGIVSQEPVLFGTTIAENIRYGREDATDADIEQAIKEANAYDFISKLPDKLNTMVGERGAQLSGGQKQRIAIARALVKNPKILLLDEATSALDTQSESIVQAALDKARAGRTTIVIAHRLSTIRSADIIAGFSEGRVVEQGSHRELMAKKGVYYSLVTQQTSGRQNEELDANEDDTQDDSEEETGEDSSDPEILEGGVEMKLERGSFRKSLKRSSKRRSSRKKSKKSRKDKKAKKEEIPEMPFTKILALNKPDWPYLVVGTFASLVGGAVYPCVAILFAKIIGVFAEPDPEVKRQKTMMFSLLYLLIGVVAFLTYFFQGFMFGKSGELLTMRLRSQAFKAIVRQEIGWFDDNNNAVGILTTKLATDASLVKGAAGSRLGLATNTICALLIAVIVAFVFCWQLTLLILACVPFLTGANFIQLRATAGHTSKDQSALEMSGKISTETVENFKTVVALTREDVFFHKFIDSLSTPYKASLCKAPIYGITFALAQAIPYLVNAAIFRFGAWLIAHCYTEYENVFLVFSVIVFAAMNIGQSSSFAPDFAKAKAAAGRIIQLLEKKPEIDIYDESGERPSTFSGNIDFKDVQFSYPTRPNVKVLQGLNVSVRQGQTLALVGSSGCGKSTTIQLLERFYDPAGGQVLVDGRDSKSVNLAWLRTQMGLVSQEPILFDCTISENIQYGDNSRTVTQEEIEEAAKKANIHNFILTLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRKPKLLLLDEATSALDTESEKIVQAALDEARLGRTCIVIAHRLTTIQNADIIVVVQNGKVVEQGTHAQLMAKQEAYFALVNAQVSAH
Protein: Ribonucleoside-diphosphate reductase subunit beta nrdF2 (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase nrdF2) (Ribonucleotide reductase R2-2 small subunit) (P9WH71)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Two genes for this protein are present in M.tuberculosis; this is the active form. When coexpressed in E.coli with nrdE the 2 proteins complement a temperature-sensitive E.coli mutant.
Interaction partners:
- Ribonucleoside-diphosphate reductase subunit alpha
- Protein NrdI
- Vitamin B12-dependent ribonucleoside-diphosphate reductase
- Glutaredoxin-like protein NrdH
- R2-like ligand binding oxidase
- Uncharacterized protein
- Thymidylate kinase
- Cytidylate kinase
- Adenylate kinase
- Nucleoside diphosphate kinase
Sequence:
MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENRNLQRKAEIVLQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDDDWDF
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (E1JGN0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MEATTTTTPDLNRGDATRKSVRLYAARKGAAPAPPKLSVAPSSNQNSNHSSNNNNSSSNLPETEKEMELRQTHLANKDLDGATEDDSIVELRRRDAQATPLPRIAVSALPTLQPHPTPKERQKPPMPRLLSTEDDAGVSFALGSIEKHIHNVEESFKQQQQNQQSQSSMDVMKLEIKRKQSKRYGETENLLRPGISDMSSENDFQYLGGRRAGELDDSNELMLSEFQRGSDGRNSIGAYSKNSAAAANGANAVKAKLARTASDTKNNDTVLAMRATFKQKQHLQDEKQPAVWRPAGTGPTPAARSSSSTTSTSGSASRGGSSSSVVDGVAPSKLTATTISASKRREENLRQFEALLAQKSSHRHGASGASGTGSNAASSKRRSDRPIVAPIPPYNSSRAEHVTSSTRHSVDPRSHSGHESRSGTASTHPPVGHHPTSRVPSVVANRSNVYSNNAAQGSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEEDELKPYIEPKADLADPKRIGKTEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDGSRSGSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISASSTKPSRRASSGAETLRVGPTNAAATVAAATGAVGAVNPSNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQRPASATQKMLTTADTTLNSPAKPRTATKYDPTNGNRTVSGTSGIIPRRSTTLYEKTSSTEKTNVIPAETKARNNTALEYSGTSGASGDSSHPGRMSFFSKLSSRFSKRPTIADEAAKPRVLRFTWSMKTTSPLMPDQIMQKIREVLDQNNCDYEQRERFVLWCVHGDPNTDSLVQWEIEVCKLPRLSLNGVRFKRISGTSIGFKNIASRIAFDLKL
Protein: Zinc finger protein 3 homolog (Zfp-3) (Zinc finger protein 752) (Q96NJ6)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MGTENKEVIPKEEISEESEPHGSLLEKFPKVVYQGHEFGAGCEEDMLEGHSRESMEEVIEQMSPQERDFPSGLMIFKKSPSSEKDRENNESERGCSPSPNLVTHQGDTTEGVSAFATSGQNFLEILESNKTQRSSVGEKPHTCKECGKAFNQNSHLIQHMRVHSGEKPFECKECGKTFGTNSSLRRHLRIHAGEKPFACNECGKAFIQSSHLIHHHRIHTGERPYKCEECGKAFSQNSALILHQRIHTGEKPYECNECGKTFRVSSQLIQHQRIHTEERYHECNECGKAFKHSSGLIRHQKIHTGEKPYLCNECGKGFGQSSELIRHQRIHTGDKPYECNECGKTFGQNSEIIRHIRIHTGEKPYVCKECGKAFRGNSELLRHERIHTGEKPYECFECGKAFRRTSHLIVHQRIHTGEKPHQCNECARTFWDNSELLLHQKIHIGEKPYECSECEKTFSQHSQLIIHQRIHTGEKPYECQECQKTFSRSSHLLRHQSVHCME
Protein: Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) (Q38FV7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03017, ECO:0000256|PIRNR:PIRNR038800}.
Interaction partners:
- Kynurenine aminotransferase, putative
Sequence:
MDRNDPLQVHRDAFNIPKRRDGSDHVYLCGQTLGLQHKDVESSVAGALKRWRELGVLAEFQHPNPWAEVDRLGRKEIAEIVGAQESEVITMNSYTVNLHLLLIAFYKPKGNRRLVMMGNYALPNNVYAVMSQLEARGLNPAEDLITVCAPKDEDGKDSPAHIPMTEYLSIIDKRGSEIAVILLSALHFITGQLVDVQAITKAAHAKGIIVGVDCAHAVGNVPLKLHEWEVDFASWCTYRYLNSGPGNLAGAFVHTKHTQVGSELKTLRGCRGHEPRDLIDPSYKFEPAEGAAGFQLSNVSVLGMMALLPSVRLIAKVGMDSLREKSLLLTSYLELLLGELVPPGSIRLLTSVDPSQRGAQLTIRILPNKLSASLTPRASYGGESESDAECMERYLRDVGIIVSTCSTDLVFLAPVPLYNTFKDVLLAARAIAECF
Protein: AT5g05220/K18I23_2 (Q940U2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEAISQTCTKIITNPSQRIYKTSSPVTAIPQTKLSLKVKKERWVAAARCVASGSDYAAAMEPITPEEEEELTQRRGICGGEVNRGVWELLECLEKEAIMGNDDGRDPRDYNRRAKIFDKSSKIFKNLNEQRDQAPVDYLEKEAIMGADDGKDPKDYNRRAKIFDKSSKIFKNIKEQREQSPE
Protein: Conserved integral membrane protein YrbE1A (O07412)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Mce-family protein Mce1F
- Mce-family protein Mce1A
- Mce-family protein Mce1B
- Mce-family protein Mce1C
- Probable ribonucleotide transport ATP-binding protein mkl
- Mce-family protein Mce1D
- Possible Mce-family lipoprotein LprK
- Conserved integral membrane protein YrbE1B
- Probable fatty-acid-CoA ligase FadD5
- Probable conserved Mce associated membrane protein
Sequence:
MTTSTTLGGYVRDQLQTPLTLVGGFFRMCVLTGKALFRWPFQWREFILQCWFIMRVGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQLGPLTTVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLASMLVATLLNGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVVIATIKAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVIALFAVNVILTTIGVRFGTGR
Protein: S-layer protein A (I0BWH5)
Organism: Paenibacillus larvae
Interaction partners:
Sequence:
MRNMGSAISNNTQNEKQSRGGEKKVMKKSLSVIVSSAMALSMFSSVAFGAKIDDFKDLKDLSAKDKAKFAAMIDANILHGLTSDYFGLYEATNRAQFARVAADVFKLKVDTSLEKSSFSDVSKEDPANGYALPYIEAAKDNGIAAGYEDGTYRPDKILTKEELATLLVKGLGFKDEAEAATGSDPSVSDWAQGYVKVAVEKGIMNNDTNGMFNGQQLVNRYMLVTSTYPVFEKNYQQIVIEGAKVTVNSDDTATVTGTAKNAITVKVTVGDTTKEVQVKEDGTFSYTTDKLPTGDTTISLVAYNGENKSAQVDLVATIGEAAVNSVTMLNEKTAEVKLNKSIGDVTRENIVVKQKDGERQYVQAVKWDENKQVATLTFFNDLPNNKDFTIELKSGSSVAKGEFKVAITEVSSIVLNDMTVPFDSPTPIEYKVLDANGVDITASTKVTLNSTKPDVIVDNKITLAKDDVVFVQAEATKKDGSKVLSKQIRVVAEGTEAVTLDKFTIAAKGSADFDSPNTFITEDKSDQFIQIQVKDKFGKEATTQGARFESLNKDVALVDRSTGAITPIKPGKVDVRVKVGAVDQVVSFEVGAKAVAKTIELDKSSILISTAAPTETVNIVVKDQYGNEFKKDELAAISKDTNVAKADLDKNKNLVIEAVNSGATTVEVKLGDITRTVTVEVKQPGAVASYKLEGFVKELDQYKGKDNENIDQMTLNVAGYDENGVKAVADVKAEYTVTDKDGKEVEKAVNNNKIEAKNLTAGETYTLTVKVGTLTVATESFKVINTEVKAVYGFNRIKDAITVKESKDLIETLNAENRTAFEIVKDGVSIENAKIQSLKFFSDNSEVVASAKDGAKKAELKADGTASILITEVTVELNNEPEQTITTNSLMEVNVKSHAAELEKAKAAAMTKIENAEKSVNESSEKADNAVKDAQKAYDEAIPEQKEAAKKELDAKSAIFRQVEKEATKVSEAKIAYEKATTVDAVKAEVAKAVKAAEDAGNLVKNL
Protein: Glial fibrillary acidic protein (GFAP) (P03995)
Organism: Mus musculus (Mouse)
Function: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P14136}. Note=Associated with intermediate filaments. {ECO:0000250|UniProtKB:P14136}.
Interaction partners:
- RNA binding protein fox-1 homolog 3
- Allograft inflammatory factor 1
- Myelin basic protein
- Oligodendrocyte transcription factor 2
- Tubulin beta-3 chain
- Neuronal migration protein doublecortin
- Macrosialin
- Protein S100-B
- Peroxidasin homolog
- Caspase-3
Sequence:
MERRRITSARRSYASETVVRGLGPSRQLGTMPRFSLSRMTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNFAQDLGTLRQKLQDETNLRLEAENNLAAYRQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKDSKQEHKDVVM
Protein: Interleukin enhancer binding factor 3 (K7EKJ9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELL
Protein: GRB2-associated-binding protein 3 (GRB2-associated binder 3) (Growth factor receptor bound protein 2-associated protein 3) (Q8BSM5)
Organism: Mus musculus (Mouse)
Interaction partners:
- Growth factor receptor-bound protein 2
- Tyrosine-protein phosphatase non-receptor type 11
Sequence:
MSTGDTVCMGWLIKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSNKPIRVIDLSECTVWKHAGPGFIRKEFQKNFVFIVKTTSRTFYLVAKTEEEMQVWVHSISQVCNFSHLEDGADSMESLSHMPSSFQPSPASSLHTVHVANSALLKDDRNTNSVVTEETRRESEFLFLPDYLILSNCETGRLHHASLPTRCDSWSNSNHSLAQTSFDDVFLDGLQPFISNNLVHPLHHGKVSQDFPSIRPQASLIWNREINGPSRNLMSSSPLLESSLNPTVHVEEKQVSLPSGVKELNIMSNTPPPRPPKPSYLSEQRQDQPLLTGHSSNKKPGYTMVPRRISLSGLDHVGSWKGDVQSQSLRHRDKRLSLNLPCKFSPIYPTASPSAEDSYVPMSPKGTASELRPHCSQDDYIPMSSSMLPELPADLEPPPVNRNLKPQRKSRPPPLDSRNLSTIQEHTSLTRTYTVPCNRTSFLSPQRNGINCARLFSTPSEEEEEEEEEEEEEEEEEKYIQMEEYGTVSSLSRSALSWTKKFSLDYLALDFNSTSPAPVQKKLLLSEEQRVDYVQVDEQKTQALRSTKQEWTDERQSKV
Protein: Placental protein 13-like (Charcot-Leyden crystal protein 2) (CLC2) (Galectin-14) (Gal-14) (Q8TCE9)
Organism: Homo sapiens (Human)
Function: Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis.
Subcellular location: Nucleus {ECO:0000269|PubMed:11997112}.
Interaction partners:
Sequence:
MSSLPVPYTLPVSLPVGSCVIITGTPILTFVKDPQLEVNFYTGMDEDSDIAFQFRLHFGHPAIMNSCVFGIWRYEEKCYYLPFEDGKPFELCIYVRHKEYKVMVNGQRIYNFAHRFPPASVKMLQVFRDISLTRVLISD
Protein: RNA polymerase sigma factor FliA (RNA polymerase sigma factor for flagellar operon) (Sigma F) (Sigma-28) (P29248)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes (By similarity). Required for the flagellin gene (fliC) expression.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00962}.
Interaction partners:
- Negative regulator of flagellin synthesis
- Antiactivator FleN
- Flagellar basal body rod protein FlgB
- Flagellar motor switch protein FliM
- Flagellar hook-associated protein 1
- Basal-body rod modification protein FlgD
- B-type flagellar hook-associated protein 2
- Flagellar biosynthesis protein FlhA
- Flagellar motor switch protein FliG
- B-type flagellin
Sequence:
MTAASGVRMYSKAQAQNSQEQLIQRYAPLVKRIAYHLLGRLPASVQVEDLMQAGMIGLLEAAKKYDAGKGASFETYAGIRIRGAMLDEVRKGDWAPRSVHRNTRMVTDAIRAIEARTGRDAKDHEVAAELQLSLEDYYGILSDTQGSRLYSFDDLLQDGEHGLPEDTSLSHNEPIHGLLDERFQAALADAIAKLPERERLVLALYYDEELNLKEIGEVLGVSESRVSQLHSQCAARLRARLADWRSA
Protein: Myricetin 3'-O-methyltransferase 4 (SlMOMT4) (EC 2.1.1.267) (A0A088MF62)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Flavonoid 3'-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as myricetin derivatives, aroma compounds possessing antioxidant properties and exhibiting pharmacological activities such as anti-carcinogen, anti-viral, anti-thrombotic, anti-diabetic, anti-atherosclerotic, and anti-inflammatory effects. Catalyzes S-adenosylmethionine-dependent regioselective 3'-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates, including myricetin, thus producing 3'-methyl myricetin (laricitrin).
Interaction partners:
Sequence:
MALSMDNIVISNEEEIYMMKAMHIPCGLYLNMVLRAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSFLTCNITKNDDGNVHTSYNLTPLSQSLISDKDGSSLAPFLLLHSESVVVNSCFLLKDAILQGEVPFNKAYGMNAFEYTKKDSRMNGLFNKAMQNVTCIEMKKIVECYNGFEGVKETIDVGGGLGISLASIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMLKSVPQGELIILKEILHNWDDEDCVKILKNCWRALPNDGKVVVIEQIQPEYPETNLLSKHLFALDISMMIMFHGGKERTKQQFEDLAKQAGFTSIKVMARAYYYWVIEFYKY
Protein: Peroxisomal targeting signal 1 receptor (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1) (A0A0S2Z4F3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Peroxisome matrix {ECO:0000256|ARBA:ARBA00004253}.
Interaction partners:
Sequence:
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Protein: ATP synthase subunit C lysine N-methyltransferase (EC 2.1.1.-) (Protein N-lysine methyltransferase FAM173B) (mFam173b) (Q9D1Z3)
Organism: Mus musculus (Mouse)
Function: Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C, ATP5MC1 and ATP5MC2. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. Promotes chronic pain. Involved in persistent inflammatory and neuropathic pain: methyltransferase activity in the mitochondria of sensory neurons promotes chronic pain via a pathway that depends on the production of reactive oxygen species (ROS) and on the engagement of spinal cord microglia.
Subcellular location: Mitochondrion membrane {ECO:0000250|UniProtKB:Q6P4H8}; Single-pass membrane protein {ECO:0000255}. Note=Localizes to mitochondrial cristae. {ECO:0000250|UniProtKB:Q6P4H8}.
Interaction partners:
Sequence:
MERVGTPEEERQAGPVLPTSLESDSSKRTSWGFLITGVVGGALLTVYAVATPFITPALRKVCLPFVPATSKQVENVVRMLRHRRGPLVDIGSGDGRIVIAAAKEGFPAVGYELNPWLVWYSRYRAWRAGVHGSAKFYISDLWKVTFAQYSNVVIFGVPQMMPQLEKKLELELEDGARVIACRFPFPRWTPDHTTGEGIDTVWAYDMSAQRGRGGRPNQEWVGQKNLSETAGLQASSSETRSKLLDVE
Protein: Liprin-alpha (LAR-interacting protein alpha) (Synapse defective protein 2) (Q21049)
Organism: Caenorhabditis elegans
Function: May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. This may be in association with the liprin-beta protein hlb-1.
Subcellular location: Synapse {ECO:0000269|PubMed:10517634}. Note=Presynaptic region.
Interaction partners:
- Rab-3-interacting molecule unc-10
- Variant SH3 domain protein
- Arf-GAP domain-containing protein
- Ras-related protein Rab-3
- ELKS/RAB6-interacting/CAST family member 2
- Phorbol ester/diacylglycerol-binding protein unc-13
- Liprin-beta homolog
- Arginine/serine-rich protein PNISR
- Rho GTPase-activating protein syd-1
- Protein lin-2
Sequence:
MSYSNGNINCDIMPTISEDGVDNGGPIDEPSDRDNIEQLMMNMLEDRDKLQEQLENYKVQLENAGLRTKEVEKERDMMKRQFEVHTQNLPQELQTMTRELCLLKEQLLEKDEEIVELKAERNNTRLLLEHLECLVSRHERSLRMTVMKRQAQNHAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVAMERVATLEEELSTKGDENSSLKARIATYAAEAEEAMASNAPINGSISSESANRLIEMQEALERMKTELANSLKQSTEITTRNAELEDQLTEDAREKHAAQESIVRLKNQICELDAQRTDQETRITTFESRFLTAQRESTCIRDLNDKLEHQLANKDAAVRLNEEKVHSLQERLELAEKQLAQSLKKAESLPSVEAELQQRMEALTAAEQKSVSAEERIQRLDRNIQELSAELERAVQRERMNEEHSQRLSSTVDKLLSESNDRLQLHLKERMQALDDKNRLTQQLDGTKKIYDQAERIKDRLQRDNESLRQEIEALRQQLYNARTAQFQSRMHAIPFTHAQNIVQQQPQASIAQQSAYQMYKQQPAQQYQTVGMRRPNKGRISALQDDPNKVQTLNEQEWDRLQQAHVLANVQQAFSSSPSLADVGQSTLPRPNTAVQHQQDDMMNSGMGMPSGMQGGMQGGMGGGQDAQMLASMLQDRLDAINTEIRLIQQEKHHAERVAEQLERSSREFYDDQGISTRSSPRASPQLDNMRQHKYNTLPANVSGDRRYDIYGNPQFVDDRMVRDLDYEPRRGYNQFDEMQYERDRMSPASSVASSTDGVLGGKKKRSNSSSGLKTLGRFFNKKKNSSSDLFKRNGDYSDGEQSGTEGNQKADYDRRKKKKHELLEEAMKARTPFALWNGPTVVAWLELWVGMPAWYVAACRANVKSGAIMSALSDQEIQKEIGISNPLHRLKLRLAIQEMVSLTSPSAPRTARLTLAFGDMNHEYIGNDWLPCLGLAQYRSAFMECLLDARMLEHLSKRDLRTHLRMVDTFHRTSLQYGIMCLKKVNYDKKVLADRRKACDNINTDLLVWSNERVQRWVEEIGLGVFSRNLVDSGIHGALIALDETFDASAFAYALQIGSQDVPNRQLLEKKFIGLVNDHRQQSDPHPRSGSSRKNDSIAKSYEFHLYT
Protein: High affinity cysteine transporter (Q12235)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High affinity cysteine-specific transporter. Major contributor to cysteine transport when cysteine, at low concentrations, is provided as the sole sulfur source.
Subcellular location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- Alpha-ketoglutarate-dependent sulfonate dioxygenase
- Uncharacterized transcriptional regulatory protein YLL054C
- Putative uncharacterized transporter YOL163W
- Putative uncharacterized transporter YOL162W
- Glutaredoxin-8
Sequence:
MSKVDVKIGADSISSSDEILVPSRLADVTLAFMEENDAAVPEITPEQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNTLFYVGFAIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLTESVVIPILITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHITNPSISLWKIFTIIIGGLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKKSQFREAMKDYITWLFGLFFLLQQLANNLPYQQNLLFEGMGGVDALGSTLVSVAGAGFAVVCAFIATLMLAKWKNISALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAGQIFGIPFIIALSWASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQIVLSFSLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDRIQLIESENPSSIEEGKVVTHENNLAVFDLTDLENETFIYPL
Protein: TSC22 domain family protein 1 (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein) (P62501)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional repressor (By similarity). Acts on the C-type natriuretic peptide (CNP) promoter (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62500}. Nucleus {ECO:0000250|UniProtKB:P62500}. Cell membrane {ECO:0000250|UniProtKB:Q15714}; Peripheral membrane protein {ECO:0000305}. Mitochondrion {ECO:0000250|UniProtKB:Q15714}.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm {ECO:0000250|UniProtKB:Q15714}. Nucleus {ECO:0000250|UniProtKB:Q15714}. Mitochondrion {ECO:0000250|UniProtKB:Q15714}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000250|UniProtKB:Q15714}. Nucleus {ECO:0000250|UniProtKB:Q15714}. Mitochondrion {ECO:0000250|UniProtKB:Q15714}.
Interaction partners:
- Nuclear receptor-binding protein
Sequence:
MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGGGSASALSAAGTGVSGAAPSSEDFPPPSSLLQPPPPAASSTQGPQPPPPQSLNLLSQAQLQGQPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHHIHHGHHLHHGHHHSSHAAVASTSVPGGPPPTSPVSRKLSTAGSSDGGVPVPPTSAVSSAGLPASVMTSIRAPSTPGSIGVNSVTGTNATNNVNIAAVGGFSPGVANSVHPNAVSISGGPGVTSGVNVNVLSGMGNGTISSPVLNAAAGITVGVVSSQQQQPQQPPPTVNTSRFRVVKLDSTSEPFKKGRWTCTEFYERENAVPGPEGVAINKVVETVKQTPTEASSSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQPLPPAPPGLQGVALQQLDFSSPGPQSISQSQMSQVQLQPQELSFQQKPNLQPVPLQATMSAATGIQPSPVNVVGVTSAVGQQPSISSLAQPQLPYPQPAPPVQTPLPGAPPQQLQYGQQQPMVPTQIAPGHGQPATQNPPSEYAQQQPIFQAAMSSGQSSSTGTGASVIPVAQPQGIQLPVQPTAVQAQPAGATGQPIGQAPTAVSTVPAGGQIASIGQQANIPTAVQPPSTQVTPSVVQQGAPPSSQVVLPAPTGIIHQGVQTSAPSLPQQLVIAPQSTMVAVPPQTQGVEAVAHGVVSHQLPTGSPLPSASTISVTSQVSSAGPSGMSSVPTNLVPPQNIAQPPATQNGSLVQSVSQSPLIATNINLPLAQQIPLSSTQFSTQSLAQAIGSQMEDTRRPAEPSSGGLPQTLSGDSGGVSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGSTA