wanglab/gogpt-training-data huggingface dataset:
Protein: Delta-VPH (Thermostable hemolysin) (O87079)
Organism: Vibrio cholerae
Interaction partners:
Sequence:
MKPLPCLADLTLEVITPTHPRWNEAIKLVDERYQQAFDAHLTAYMPAYLALLDKQVMKSVCGYRIAEQEPLFLEQYLDEPADRLLAQRFACPIPRGKLIEFGHLASFGRGLSAFHFRLMAQQLVAMGFEWCIFTATDPLHALMRRFGLQLTLIAQASPARIPNASQIWGTYYQHRPRILAGNLVHGCTHLNQLHLNQKQA
Protein: Transporter (F1LQW0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MLLARMKPQVQPELGGADQLPEQPLRPCKTADLLVVKEHNGVQCLLASQDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLVAQRDVRQFQLRHWLAI
Protein: Ribosomal RNA-processing protein 12-like conserved domain-containing protein (Q386Q9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Bystin, putative
- Periodic tryptophan protein 2, putative
- Bms1-type G domain-containing protein
- CCAAT-binding factor domain-containing protein
- Nop14-like protein
- Nucleolar RNA binding protein, putative
- KRR1 small subunit processome component
- Serine/threonine-protein kinase RIO2
- Nucleolar complex protein 2
- RNA-binding protein, putative
Sequence:
MKPPSAAAQRGKGAFASKSTRTPLKQLRKGTNLSRQKLLRLQREALMVKRQKTEVQKSAQKREVTKRVLAAQNKKIHKTFDQGILQSVQGGLVESIESLGEPVTPLSLFMAASTALSLSPEKHHVPYILAILSACAPRLSQGMLLHQLEPSIATVERVIAENIASNYLAVAKAMKFSQQLVLSVESPSMKVLNVFSRLEPSKMQVDIMKMYLVAFRKLLERSAAHSPTDESIGGTRNNVSEGGVYILSDNQNFFVQGVRHFAALCVSNFTDAPLSVVSSTTAEFTVLIRRTISPYIVESAEGREMIDEIVSNRLLELLKPHCQVYWSYALEILEALFNRINYLKRTAAGDAMLLTRRFPSFHFLLRVLNKMRRMDDGKLNGAIERAMVALGRGMTVREFVDIIPFDPRQVYEAELRGTAIGGAYPSPDDDPWINSYVMGVLRRTASHDSLPFFVEYFFPLIQFTSGVALEYGRQQQVELAAKWTALLQQYWRLAIGFCQYPRIVDKDSFRDVAKQLVGLLPHPLFADAGATALHMLCSGYYDLASTEPVDDDDDINDGVGEAEEQEKGWLADEQQEEDSSNRVRAKVGLGHKNSLDEDDLFLSLNDPTWNRHVYHGISQTTAKDVCGNVFSRFSANIMPKLCNTFETHNSTSILRAIHSFSRVCSREVMQVILKGILDVGANIAHKQQLLQEKAEERGDKVVKKAGYAPLTGKRRMILDIACAVVEQLEKEHLVKLFDDIIEPVLMDPAPESRLLQKKAYKLLYSMFEFRSKDIFPLFTRISGILSVGRQNVTISGIKMRLRCIVWALDACKMFYPDHVTTMIRAIVGETITLSRERSSEVRTLSMDLLEKMHRYLIGAGNPVNTLLHLVLAGFSGKTTWMISSTLVAMAKIVSVAHEELPEKDLDAAVALGIRMMESTALDVRSAAAMFVRMLLKMMKRSRRVGAAVEKSISKLMLAIALTTSQPRVSSNTRLQMRVILEKCIKRFGYERLEPTFPIGSKNFLRYTQKMMKREQKKEERELRKRTEERKNEFDRLFLGAGMKAGTEDDAERDLLQAGGLTSFVSAYASPSFNAGSAGRGYNGDEDDDELDNMHIEFQEGKLHIMTAEEKRKQDDRRRREEMAKKLLRSRNGLVHADALNEGAVAQRGKRTRNDVEDFENDELLLRYGDKINNEGAAAAARRVVGPGVNQVERLREQKQEKRELKRARVEADIIRGDEFKGTGEGDVRRGGLAPYAYVPLNRQYMNRRHQREAIQRLEVVAQRSNLKGNKAKLSKLAKQRRAEKKQKVNLSQ
Protein: Polymer-forming cytoskeletal protein (Q9A421)
Organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus)
Interaction partners:
- Peptidase, M23/M37 family
Sequence:
MSSLKLPADNPTFLAMVGSCQVWSPGLDNAGKRPRSCCLGLPNAHFETRSPPMFAKKKETPAKLALTPLEPQRAATPQVAQPQPQPAPAPARPKPASLIAQGLTIRGDVVGDIEVHLDCVVMGDVKVGKLIVGPNARIEGAVVAQAMEIHGMVIGAVTAQSVRLYGTARVDGDITHEQLAMEPGAEFQGRSLKFRRPAPTPQPGQQAPAAPTPAAPPTPPSASQTPYNHSAH
Protein: Ras-like protein rasY (EC 3.6.5.2) (Q55CB7)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Probable serine/threonine-protein kinase roco5
- Rac guanine nucleotide exchange factor B
- Uncharacterized protein
Sequence:
MTTNKSNGNLVKLCIMGDGGVGKTSVTIQFISNHFVHYYDPTIEDSYRKQCLIDDQVYMLDILDTAGQDELTAMRDQWIRSCEGFILVYSVTSRSSFDQVQFFREQIIRVLDRDDVPIMMIGNKSDLDDERQVTFQEGKDLARCLGMSFMEVSAKTRLNVEEVFNETVRCVKRREESLLKKDNSKDGKGDHSKKSSIFKKLNQKVNGAKISICKMM
Protein: F-box only protein 2 (Q80UW2)
Organism: Mus musculus (Mouse)
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
Subcellular location: Cytoplasm. Microsome membrane; Peripheral membrane protein; Cytoplasmic side.
Interaction partners:
- S-phase kinase-associated protein 1
- F-box/WD repeat-containing protein 1A
- F-box only protein 4
- Cullin-1
- S-phase kinase-associated protein 2
- F-box/WD repeat-containing protein 7
- F-box only protein 6
- F-box/WD repeat-containing protein 11
- E3 ubiquitin-protein ligase CHIP
Sequence:
MDGDGDPESVSHPEEASPEEQPEEAGAEASAEEEQLREAEEEEEAEAVEYLAELPEPLLLRVLAELPATELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGSADEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWSDVEHGGDGWRVEELPGDNGVEFTQDDSVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRTDAGSLYELTVRLLSENEDVLAEFATGQVAVPEDGSWMEISHTFIDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
Protein: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1) (P61803)
Organism: Homo sapiens (Human)
Function: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes. Loss of the DAD1 protein triggers apoptosis.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3
- Oligosaccharyltransferase complex subunit OSTC
Sequence:
MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
Protein: Tubulin beta-4A chain (Tubulin beta-4 chain) (Q9D6F9)
Organism: Mus musculus (Mouse)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Tubulin alpha-4A chain
- Tubulin alpha-1A chain
- Tubulin alpha-1C chain
- Tubulin alpha-1B chain
- Tubulin alpha-8 chain
- Tubulin alpha chain-like 3
- Tubulin alpha-3 chain
- Microtubule-associated protein
- Gap junction alpha-1 protein
- Serine/threonine-protein kinase PLK1
Sequence:
MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEEEVA
Protein: Pipsqueak, isoform N (A0A126GUM1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00320}.
Interaction partners:
Sequence:
MAAVRGHQYFSLRWNNYQNTMTSVFQQLREDLSFVDVTLSCEHGSLKAHKVVLSACSTYFQKLLLENPCKHPTIILPADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLKIKGLCETAENADDLNDAATATITVSENIQQAVVGNIVNAAIVPGAPSPSLEQQQQHHQQQQQQQAQEQHQQQQVHAQQQQQQQQQINAALLTQHGVSSGSVSLSGQLLSSSASGSSGSLAGGQQASQTPSGLQPTPRKSRLKRSKSPDLSSGGGAGSSGGSSSGSTQQQPQPAHHHHPQTILIQGQNPNSIVSLQQTADGNYIPVSGSGDDSDAEDHEHEHNHGHGHGHGGHTHGHGHSHEHSHDHEHEHKPNKICKTEHSVASPASNSSSASNNAAGVSGVTSTGQAIVTQIVVARDGKDTKNMTSLGMGMNGGLLGVPMGFLDFTPEPPAPSATPVTVTEHVDLSCNPSTDTRDLSNTTEPLDIDNHLAQQIHRLDQSPMHSISHHHTGDESNSNLVQHIKSEVIEAKHLAAQHHALSQAQQQHAHHQAHQQHQQHQQQQHQQQQQHLHAQQLLAQSQLQQQQQQQQQQQQHHQQQQQQAAAAAAAAGVHGQHGGHVTHADIGGATVMEIDPSQIKHEPGMIITPEIVNMMSSGHMDMYNSDTSEDSMMIANGSPHDQKEPHYTNLDQQHGLGGSVCGPGPGGAGGGGGMSGGAGSGSGEKALDALKNQNMSLTKASAIYGIPSTTLWQRAHRMGIETPKKEGGTKSWNEDALQNALEALRSGQISANKASKAFGIPSSTLYKIARREGIRLAAPFNAAPTTWTPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYGRCKREGIELSRSNPTPWSEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYGRFKRGKYDVVANTSGVALLNTSGNTTGSIEIIEHSQENSQQFPYSPSPHPPTPQHHSTPQHHSSAQQGPPTPQHMQQHVVHMQQQQQQQQQQSPHPGHHPQHMQQDVVTSSSQVVHSQQQQQLQQIYQHHGTPERS
Protein: Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) (P26637)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm.
Interaction partners:
- Isoleucine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase, cytoplasmic
- Glutamate--tRNA ligase, cytoplasmic
- Glutamine--tRNA ligase
- Methionine--tRNA ligase, cytoplasmic
- Isoleucine--tRNA ligase, mitochondrial
- Putative proline--tRNA ligase YHR020W
- Lysine--tRNA ligase, mitochondrial
- Arginine--tRNA ligase, cytoplasmic
- Valine--tRNA ligase, mitochondrial
Sequence:
MSSGLVLENTARRDALIAIEKKYQKIWAEEHQFEIDAPSIEDEPITMDSEELHRTYPKFMSSMAYPYMNGVMHAGHCFTLSKVEFSIGFERMNGKRALFPLGFHCTGMPILACADKLKREAELFGKNFDNVPAEEEEIKEETPAEKDHEDVTKFKAKKSKAAAKKGRGKYQFEIMLQLGIPREEIIKFADAKYWLTYFPPLCESDCTSLGARIDWRRSFVTTDANPYYDAFIRWQMNKLKAAGKIKFGERYTIYSEKDGQACMDHDRQSGEGVTPQEYIGVKIEALEFADDAAKIIDSSSDLDKSKKFYFVAATLRPETMYGQTCCFVSPTIEYGIFDAGDSYFITTERAFKNMSYQKLTPKRGFYKPIVTVPGKAFIGTKIHAPQSVYPELRILPMETVIATKGTGVVTCVPSNSPDDYITTKDLLHKPEYYGIKPEWIDHEIVPIMHTEKYGDLTAKAIVEEKKIQSPKDKNLLAEAKKIAYKEDYYTGTMIYGPYKGEKVEQAKNKVKADMIAAGEAFVYNEPESQVMSRSGDDCIVSLEDQWYVDYGEESWKKQAIECLEGMQLFAPEVKNAFEGVLDWLKNWAVCRTYGLGTRLPWDEKYLVESLSDSTIYQSFYTIAHLLFKDYYGNEIGPLGISADQMTDEVFDYIFQHQDDVKNTNIPLPALQKLRREFEYFYPLDVSISGKDLIPNHLTFFIYTHVALFPKKFWPKGIRANGHLMLNNSKMSKSTGNFMTLEQTVEKFGADAARIAFADAGDTVEDANFDESNANAAILRLFNLKEWAEEITKESNLRTGEITDFFDIAFEHEMNALIEKTYEQYALTNYKNALKYGLFDFQAARDYYREASGVMHKDLIARYIETQALLLAPIAPHFAEYIYREVLGNQTSVQNAKFPRASKPVDKGVLAALDYLRNLQRSIREGEGQALKKKKGKSAEIDASKPVKLTLLISESFPEWQSQCVEIVRKLFSEQTLDDNKKVREHIEPKEMKRAMPFISLLKQRLANEKPEDVFERELQFSEIDTVKAAARNVKKAAQALKIAEFSAISFPYGAKTGKDIFTGEEVEIPPVTKIVENAVPGNPGVVFQNI
Protein: Uncharacterized protein (Q385H6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRSAAFVAGKNKSVPAERVNPFVDNSLEHVSFVCRSEAVAMQRVRRFCNELPEVLCGRSCALFEAVAFFNSRYVEATSQCVLRFSKNLPIIVSRVVKNRKKYVRYTQNKAISGFGTGSRPQRQRIEDMSMKPLVLVGALIFDQGGRCCPNAECSCSSEHSGSNYNLHNCNQSTCGAVCKEELKICDELKCVINPSDSIGDITENIGRWEAASFNRLQLELAMVDITSLISGILELNDHPLTMMNHLHLPKSTSERVSLTLQKLACGLCHHCGEHERGVTTDVEASGSHRCPEITTIADRINFCRHLAHTAASYIKGNIILVLDDHSSLVESANEVVVDEVGDITTGTKLNSVDCEKDYQVARHMSCCTAEMIQFSVSVKLSKDVEHFLDCVIAAMTRVSEEAESSVFTLPTLLELRERVVQEEFIPVGEGAGQLNADAVNEGVNCAEKYPAEAVAAAEGNLEGGSVETDSECRAANQLDFDSSRQLCEVEERCDAEYRYRGPIRCFPRIFSMDAQQELLFWKNVRKHRLYLARRAPAMNSVNIYYDCMPYDPHRHSLHHDLRRNKDELFAGWVGEAEEGVDDAVITKKELQSSAMFLEWLEDVAEQSSLNKECQRIVRESGIGYISRDPLLPLQHYLSFVKVFSAAATVRSIIESGASNDKGATSENPGLFIVVGTECDVRDGGRLLVPWWMDPLALLALLQCDDAQETRCLNGGAAASPSAAQTP
Protein: Ponticulin-like protein C5 (Q54LB9)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
- CMP/dCMP-type deaminase domain-containing protein
- PhoPQ-activated pathogenicity-related protein
- Probable phosphoglycerate mutase
- Secreted protein A
Sequence:
MKLNNSLLLLIVAIIASSNAAETFSNFQVTNSEASSPCVTTPVELKVNTCQSACDSILNVLPVTGSTSKFTFNQFGAQDTKCAATPTSSNEFTCVDGKSKVAIGTTTYSVVCVPDKTNSSESDSSDSTRIGASFALFALALLSMLAL
Protein: CADPS protein (A2RRN7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004156}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVNNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNGEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD
Protein: Solute carrier family 25 member 19 (J3QL84)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004225}.
Interaction partners:
Sequence:
MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE
Protein: Protocadherin gamma a9 (RCG49295, isoform CRA_w) (I6LBX6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MAAPARRPHCTRLVLLCALLGMLWEARARQIHYSVPEETEKGYTVGNISKDLGLEPRELAERGVRIISKGKTQFFSLSPRSGCLVTAGRIDREELCARIAPCVLSFKVLVEDRVKLYGVEVEVIDINDNAPKFEAENLVVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLDIQRGDDGTINPELVLERTLDREEEPSHHLVLTASDGGDPRRSSTALIQVTVLDTNDNAPAFDQPVNRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKMNEKQSLLFHLHENTGEMTVAKTLDYEECSLYEMEIQAEDGGGLKGRTKVVVTVEDVNDNRPEVTITSLFSPVREDAPPGTVIVLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLMTAQILDREKASEYNITVTATDRGTPSMSTEVQITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDENENAKVTYSLVENTIQGAPLTSYISINSDTGVLYALQSFDYEQFRNLQMQVKASDSGHPPLSSNVSLSVFLLDQNDNAPKILYPSLPTDGSTGVELAPRSAEAGYLVTKVVAVDEDSGQNAWLSYRLLKASEPGLFTVGLRSGEVRTARALLERDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPDILADLSSISTPADPDSDITLYLVVAVAVVSCVFLLFVLVLLALRLRRWHASSLLQDAIGGSTGVPTSHIVGVHGVQTFLQTYSQEFSLTPDSGKSHLIFPQPNYADTLISQESCGKSEPLCSSVESKFPIDDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Protein: Metalloendopeptidase (A0A1D8PQ06)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Ubiquitin-ribosomal protein eS31 fusion protein
- Oxidoreductase ENV9
- Presequence protease, mitochondrial
- CAAX prenyl protease
- Polyubiquitin
- intramembrane prenyl-peptidase Rce1
- ubiquitinyl hydrolase 1
- Protein channel
Sequence:
MIIPSLKLTTTRSSFVSVSKYYSRMSNQFTILSDDKTIEKPLLDDRSYRFIKLNNNGLRVLLINDPTTDKAAASLDVNVGSFTDKEYNISGLAHFCEHLLFMGTEKYPKENEYSNYLSKHSGSSNAYTAAEHTNYYFQVGADYLEGALDRFSQFFIAPLFSKSCQDREINAVDSENKKNLQSDMWRLYQLDKFTSNSAHPYSGFSTGNYQTLHTDPVAKGVDVRDILIDFHKQHYSSNLMSLVILGKEDLNTLTDWAIEKFSAVPNKDLSRPNYNGELVYKPQQLGKLIKAKPIMDNHKMELNFLIPDDLEDKWDTKPNGYFSHLVGHESKGSIIYYLKQKGWATDLSAGAMTVCQGTSNFYIEFQLTPKGFENWQEIIVITFQYLNFITNDEPQKWIWDEIEEMSQVNFKFKQKMEASKTVSTLSNKLYKFDEYIPASYLLSSAIVRKFDPEAIKRFGSYFTPENLRITLASQLLTGLNKQEKWYGTEYEYDDIPQELIHQIKSQPYDNNQNLHYPRPNHFIPTNFDVTKPKSKHPQVAPYLIEHNNKINVWYKQDDTFEVPKGSIEVAFHLPSSNTDINTSVMSNLAIEMLDDELNELTYFAELVGLKVKLHAWRDGFLINVSGYSHKLSNLLQEVLNNFFQFKPKQDRFESIKFKLLKNFKNFGFQVPFQQVGVYHLQLLNDKLYQQDDKIEALEKVTYEDVYQHFTQNIWQSGIFAEVLIHGNFDFAQSKQIRDIINESMENVKPWMEKYNEEQFHLQSYVLQPNETIRYEVPLKDTANINSCIEYYIQINTNTDNLKLRVLTDLFATIIREPCFDQLRTKEQLGYVVFSGTVLGRTTLGFRVLIQSERTCDYLQYRIEEFLVQFGNYINNELSTEDFIKFKHALKNIKLTKLKHLNEETVRIWSNIIDGYYDFDSRTRQVEILENITKDELVEFFNTFIAKSDNTGKLITYLKSQNPIEFTESKKLHSGIINYLYRNQIEINHELIDNLVKQYDEHKDLAVIAKELSHDINVNKDKLLKVLNKSIAQPVPEIYPTVKLVVNDKEFRKNRQLSGTPKPVNPLSKFLYNDQSHL
Protein: Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42) (Q0P483)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q86VD7}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Ribosomal protein L18
- Thymidylate synthase
- Ribonucleoside-diphosphate reductase large subunit
- Centromere protein T
- Proliferating cell nuclear antigen
- Replication factor C
- Phosphoribosylglycinamide formyltransferase.
Sequence:
MGNVVQERQGALAQGEVLPRPAASQSEGFKQGRSVLNSLVSGAFAGAVAKTAVAPLDRTKIIFQVSSNRFSAKEAYRLIYRTYLKDGFFSLWRGNSATMVRVIPYAAIQFCAHEQYKGILGKYYGFQGKALPPVPRLLAGSLAGTTAAIITYPLDMVRARMAVTPKEMYSNIMDVFVRISREEGLKTLYRGFTPTILGVVPYAGLSFFTYETLKKTHAEKTGRAHPFPYERLVFGACAGLIGQSASYPLDVVRRRMQTAGVTGHTYSTVLGTMREIVAEEGIVRGLYKGLSMNWVKGPIAVGISFMTFDLTQILLRKFQLL
Protein: Mediator of RNA polymerase II transcription subunit 9 (Q8RWA2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 27
- Mediator of RNA polymerase II transcription subunit 32
- Mediator of RNA polymerase II transcription subunit 11
- Mediator of RNA polymerase II transcription subunit 6
- ATP-dependent DNA helicase Q-like 2
- Mediator of RNA polymerase II transcription subunit 30
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 23
- Mediator of RNA polymerase II transcription subunit 8
- Mediator of RNA polymerase II transcription subunit 17
Sequence:
MDQFSGGGGNWSMIPNVQAQGNFGTPTNHDQQLFLQQQQLQQQQQQQQQQQFHLQQQQQTQQQQQQFQPQQQQEMQQYQQFQQQQHFIQQQQFQQQQRLLQSPPLQPQSLQSPPPQQTMVHTPQSMMHTPQQQQQLVQTPVQTPQQHQSLASHFHLYPMVEKLADVIENGTRDQNSDALVNELNSHFDKCQQLLNSISGSLGSKTMTVDGQKRNVEESEQLLQQRRDLIVEYRKSIEEIVTMEH
Protein: DRBM domain-containing protein (Q94239)
Organism: Caenorhabditis elegans
Interaction partners:
- Endoribonuclease dcr-1
- Ribonuclease 3
- Nonsense-mediated mRNA decay protein
- RNA helicase
- RRM domain-containing protein
- Regulator of nonsense transcripts 1
- DZF domain-containing protein
- Cytoplasmic polyadenylation element-binding protein 3
- Cytotoxic granule-associated RNA binding protein tiar-1
Sequence:
MQAVFETTLTQKMDGVMIVQETTTDLADTLENASISAEKSEQKPERLHPQHWCGQHKFEADSPTNFYDYTNAKEKEKSAMCRVAEIARFNKLRHVYNLQDESGPAHKKLFTVKLVLTEAETFEGSGTSIKRAQQASAEAALKGTKLPLPTEKPTKKRINDTTKPHRVLQNVCRTLQYQMPNYISCNPPVYPDPGCPLPEHILLPLESMALYAPPFPTLPIDPARPQGPKLQAVIVNINGKSIATGIGETYPLAKQDAAAKALAVLSPLLREHQNGSDNGFGKENIPVHKQKSVISDIHEKAYQLKVNVVFEVLKEEGPPHDRQYVVRCAFVTSGNVVKAEAVGKGKKKKSAQQEACTQLLATVEHLTPENNPVALATNVCKTQKKLAAMNREPKRKTIVKDKKMDPLYGHQINPVSRLIQVTQAKSKEHPTFELVAEHGVSKYKEFIIQVKYGDDVQEGKGPNKRLAKRAAAEAMLESIGFVKPLPPPGKSLLKKMIDCDPSLPEISHWTGPPPTAVSVSTSEPDTSEAAQLSPEQTDISEKRELSPDTEKRRVTFNSQVHACPPPGDQDYPNSIVQSLKKDAIVEGKIRRLKRSKENRRALTAEQIVELSERAQSYLQTKNTTIQSSQSSSAHHHLEQLSDFFKFSLQYTSFPQVGIDQHFTIVSIGLEAPLVGHGTGCSTTEADENAALDAIAKLKELSASKT
Protein: Endonuclease 8-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (Endonuclease VIII-like 2) (Nei homolog 2) (NEH2) (Nei-like protein 2) (Q969S2)
Organism: Homo sapiens (Human)
Function: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Subcellular location: Nucleus {ECO:0000269|PubMed:12097317}.
Interaction partners:
- Kelch-like ECH-associated protein 1
- Endonuclease 8-like 1 lyase Neil1)
- DNA repair protein XRCC1
- N-glycosylase/DNA lyase
- Endonuclease III-like protein 1
- Bifunctional polynucleotide phosphatase/kinase
- DNA polymerase beta
- Y-box-binding protein 1
- DNA ligase 3
- Flap endonuclease 1
Sequence:
MPEGPLVRKFHHLVSPFVGQQVVKTGGSSKKLQPASLQSLWLQDTQVHGKKLFLRFDLDEEMGPPGSSPTPEPPQKEVQKEGAADPKQVGEPSGQKTLDGSSRSAELVPQGEDDSEYLERDAPAGDAGRWLRVSFGLFGSVWVNDFSRAKKANKRGDWRDPSPRLVLHFGGGGFLAFYNCQLSWSSSPVVTPTCDILSEKFHRGQALEALGQAQPVCYTLLDQRYFSGLGNIIKNEALYRAGIHPLSLGSVLSASRREVLVDHVVEFSTAWLQGKFQGRPQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEEPEQCQFS
Protein: Ubiquitin-conjugating enzyme E2 variant 1B (Ubc enzyme variant 1B) (Protein MMS ZWEI HOMOLOG 2) (Q9CAB6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has no ubiquitin ligase activity on its own. The heterodimer with UBC catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. May play a role in the control of progress through the cell cycle and differentiation. May play a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Interaction partners:
- Ubiquitin-conjugating enzyme E2 35
- F-box family protein-like protein
- Membrane-anchored ubiquitin-fold protein 4
- F-box protein At5g36820
- F-box protein At5g36730
- Membrane-anchored ubiquitin-fold protein 5
- F-box/LRR-repeat protein 4
- Ubiquitin-ribosomal protein eL40y fusion protein
- Membrane-anchored ubiquitin-fold protein 1
- Membrane-anchored ubiquitin-fold protein 6
Sequence:
MGSEEEKVVVPRNFRLLEELERGEKGIGDGTVSYGMDDADDILMQSWTGTILGPHNTAYEGKIFQLKLFCGKDYPESPPTVRFQSRINMACVNPENGVVDPSHFPMLSNWRREFTMEDLLIQLKKEMMSSQNRKLAQPLEGNEEGRTDPKGLVVKCCVM