wanglab/gogpt-training-data huggingface dataset:
Protein: GH14043p (Regulator of cyclin A1) (Q9VM76)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cell division cycle protein 20 homolog
- Fizzy-related protein homolog
- Serine/threonine-protein kinase polo
- GM10285p
- G2/mitotic-specific cyclin-A
- Cullin homolog 1
- Lamin-B receptor
- Fatty acid hydroxylase domain-containing protein
- RE26969p)
- GEO01111p1
Sequence:
MSAYYRRAALRKKSPSRGSSFELEMNESGYTSFLALHNSTAETPFLLEDAEGENCRNASNTTTFFRGLNTPSGHQEQDLYWGKPYPRTQPQKKFSAEEEPFSMTPRLQDEHSLPKRRKKHFQSPHSSPKKSKKLLFPHIEEPPKNRFYGGVEKLDIVAKLAQWQPALQCILRHVGAHTLDVMTKVSPAWKQAVYRSQRDLERLQNHRLKLNLTKENPHVPKRCSHVPKANHTVPLQTSNHSSLANSAASLMDSGNSSIHLMDVDAGRVLREQTQRVKCPRCGRGSRVFISEAAKCGENLLSQTLPIGRTTSTFPCMTGPPLKRFLSLDLDEVRTSPQGPPYNFAECTSVICQFRFCVNCLCKSHPGERCLVTELDTPSKLMMPRERLTPPQRAQNRDPKITRKNSLKRLCF
Protein: Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell wall biosynthesis kinase) (P53894)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
Interaction partners:
- CBK1 kinase activator protein MOB2
- Cell morphogenesis protein PAG1
- Tyrosine-protein phosphatase CDC14
- Metallothionein expression activator
- Protein HYM1
- DBF2 kinase activator protein MOB1
- Leucine-rich repeat-containing protein SOG2
- Protein SSD1
- Serine/threonine-protein kinase KIC1
- Laminarase-resistance protein LRE1
Sequence:
MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNPYQQIPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSSGLRSVKSFQRLQQEQENVQVQQQLSQAQQQNSRQQQQQLQYQQQQQQQQQQQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFDYLTRKNAL
Protein: A-kinase anchor 110kDa C-terminal domain-containing protein (Q8BSJ2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
LKMKCGSKLFPLHGCHGKTNKELLVFSSKERHQEVDRQRKRNGSHLCKYQTCERTQDPCRNELSELYSFSASLASSITRDAKKQLTAPKVDLPKSSTDGCFFEKSECVDSSENVTGPERSKSCQPLQSHGFCQNTGYLSGYSCAENAQAIEQYARKVVGDTLELSLGPTVFHNSETTASADRITYAEKLSPLINEACRYCDLKEFHGCTRNSAQLFSKQSPFSSAKPSSRSKLSSIRQKSRIFHLDVPQIHVNLDKRAVLAEKIVAEAIEKAERELSNTSLAADSGIGQDGISFAESLTTEIMTTAVTNAGHAVSSSREIEDFQSTESLGSQQMNLSVGEDSTGSWSNLSFEDDHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNYPFPTSDSDGSDDGDDEQEDGVEDLQQNGKTLLIMNIDMEPGAVDPQLRIILQWLIASEAEVAELYFQDSAKKEFILLSKQLQEKGWKVGDVLQAVLKYYEVVEKPSREERCKSLFDWLLENAQNRLQTSMLV
Protein: Protein phosphatase 1c interacting protein 1, isoform B (Q8IMJ3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNVDLQDLSFMSTSSIDPCVGFMPSDTEVAQDSPPCSEDRAQDSFQCQDSPPRLIDMAGPYPVYSCPNVDDDCVTFEPPAGPATQFSSCQKNVLGEGNANRLCQKHSSPRLRQMHISNTRSCVLCGEDVSWLPKVAACPCCGYKPVPEFKERPYDEQATAQQILLDHLENPVENLSFDMGSVEGCSANEEHGVPEPTSEAFEAIVKDYQLLRRSIRESNTKATQSATKNPTAQEGSAQPQDLAKVFTELRDLFNVKAADENQKIQDICAEACALAKSHKKSKNRPASPERTKAGKTDPVEDACETPRKMKKRRPKVKRPYKSRYYSMYRPTERPKANVAIPDADKKVPSHMGWLWTAHPLANKPGWRPGAIRRSIRGLMSYFLKDFPVDNVPVSKYMSYYKHKMSPMSPPGEKAEDLVQVPTLHIEKKNDVYTITLRPLKDAKTLARSANPYVRMKPVQFRIVKNPLLKEIRDLKRCLKGMGFSKCSCHKPLMNCYCRSFVDKKRLLYHVRRECERRKIDSCEDELVLTDTSDSEDEFDFGVTPPAGLMRPERLKSSHVKHTETQYNESDWVNPSLYPHMPDATVQYESCVMGEREKPFNWIYGKGVIQEEPKPPKMRNIPKKPKKKKPVPGRVAGGFSGQDHQDSCVYSRVNNTTIQTKDREIRPICNPPSYSTDSELPLTGDHMRLLDQAAYPPTAPQRQQPWSREMANERKRLRVKRRTKKMVRFDPTLGPHSSDISIN
Protein: Intermediate filament protein ifc-2 (Cel IF C2) (Intermediate filament protein C2) (IF-C2) (Q21067)
Organism: Caenorhabditis elegans
Function: Cytoplasmic intermediate filaments provide mechanical strength to cells. Not essential protein, although its absence leads to mild defects in locomotion.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12204276}.
Interaction partners:
- Intermediate Filament Organize
- Intermediate filament protein ifa-1
- Intermediate filament protein ifa-2
- Intermediate filament protein ifb-2
- EB domain-containing protein
- Intermediate filament protein ifb-1
- Moesin/ezrin/radixin homolog 1
- Intermediate filament protein ifa-4
Sequence:
MSTYAAYTTSTYQGRGLASGTYASGFGQLVSGMSSAGAICTTQIRDAREREKREIGLLNDRLADYIEKVRFLEAQNRCLSHDIDILRNGFSGGGHVSGLFDAEINQAKHILEQTTAHRSTFERDITGLSAEIEVFRKKWLDAVNAVKAHREDHDVDLDRLAKIEAEISLFKRKIRIVEEDVIRIRRENDGIYNEIARIKQLTHNEIALKNERSLNVSDLLQRINLLQTENNVRIEQELVFIRRDTTADNRDYFRHELQAAIRDIRADYEAISIRNRQDIEVWYREQIRKIQDESVRVNPDLYKEELISIRTTVTNVRSRLAEVEGRNFFLERLIDDLKNNEEAKFFEISLAERDAQIATLRDQCTELSIQMEKLCDNEISLRAEIERYRILLNGANVTTYTSNTHGSGSGIAVGGVVGGSTRVISQTTRTHSSSNTSYSNVPASRGGYSISGNVGGISVGGTIGSHGASAHATGGIIGSGVQAHRGSVSSLITDKPRDRVHDEKGVDQSGRHFHSWYLGTISINQVTPSYIELKNICKIRRVDVGGFRIEQSVNGQVLGSAQINVPLILDPQEVVRFNHRHGKYLGQFFMDVDAFDNSTVARTSMYNYTEPHEERAWFVYLD
Protein: Cytidine/uridine monophosphate kinase 1 (A0A494BXC7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEEMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG
Protein: Copper transport protein (Q8IL79)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU367022}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU367022}.
Interaction partners:
- Copper-transporting ATPase
Sequence:
MCKNIYFYIILILKLFIVLADKSDNSICKPSVKISCAHNCCKNKLSFMYNCWKHYDKYSNIIKDNLQKEEDTVVQLQDHDNIDIVEHVETMPMSFQLTTHTIILFNKWETKSALSYYISLVLCFFFGIISVGFKVVRLNVEQALPKTEDTNIFKSLVLFKNNSYRMLLSFVIYSWDYLLMLIVMTFNVGLFVAVVLGLSFGFFIFGNKFVSSKKCSPDDLDVHKEFTADPACCGC
Protein: N-acetylneuraminate-9-phosphate synthase (EC 2.5.1.57) (3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase) (EC 2.5.1.132) (N-acetylneuraminic acid phosphate synthase) (NANS) (Sialic acid phosphate synthase) (Sialic acid synthase) (Q9NR45)
Organism: Homo sapiens (Human)
Function: Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
Interaction partners:
- N-acylneuraminate cytidylyltransferase
- Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
- N-acylneuraminate-9-phosphatase
- N-acetylneuraminate lyase
- N-acylglucosamine 2-epimerase
- CMP-sialic acid transporter
Sequence:
MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
Protein: Translocon-associated protein subunit delta (Signal sequence receptor subunit delta) (Q9U238)
Organism: Caenorhabditis elegans
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
Interaction partners:
- Translocon-associated protein subunit gamma
- Translocon-associated protein subunit beta
- Translocon-associated protein subunit alpha
- Protein transport protein Sec61 subunit beta
- Translocon-associated protein subunit beta
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
- Golgi resident protein GCP60
- Signal peptidase complex subunit 2
- Protein transport protein Sec61 subunit gamma
Sequence:
MLKIAVALCLVASALCAKCESPKYSASSFSTTDGFFHYKTTFITEFTLQCSNNPKNIQYTAEVNGRLIPVSISDETAKFQVSWTLEHKDAGAQTFNINIFDEEGAAQYAKNPVTKPLFTVQQSHGGLATKSPISSETVAVIIVVIGLYYAIRQKTELVH
Protein: RING-box protein pip1 (RING-box protein 1) (Pop-interacting protein 1) (O13959)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of E3 ubiquitin ligase SCF complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recruit the E2 ubiquitination enzyme, like UBC3/CDC34, to the complex and brings it into close proximity to the substrate. Component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Cullin-4
- Suppressor of kinetochore protein 1
- Cullin-1
- Chromatin modification-related protein rik1
- DNA damage-binding protein 1
- Cullin-3
- Elongin-C
- Cell division cycle protein cdt2
- NEDD8-conjugating enzyme ubc12
- Ubiquitin-like protein 1
Sequence:
MEDEMQIDKKEVEIEQKPPRFEIKKWNAVALWQWDIVVDNCAICRNHIMDLCIECQANTDSAAAQECTVAWGTCNHAFHFHCISRWLNTRNVCPLDNREWEFQRYGH
Protein: Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1) (Q9BW27)
Organism: Homo sapiens (Human)
Function: Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade. Involved in nephrogenesis.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000269|PubMed:12196509, ECO:0000269|PubMed:12718872}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:12718872, ECO:0000269|PubMed:15146057, ECO:0000269|PubMed:16807356}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16807356}. Cytoplasm {ECO:0000269|PubMed:15995708}. Nucleus membrane {ECO:0000269|PubMed:12196509}. Note=During mitosis, localizes to the kinetochores and spindle poles (PubMed:12718872, PubMed:16807356). Upon CCl2 stimulation translocates from the cytoplasm to the membrane and colocalizes with CCR2 at the front of migrating cells (PubMed:15995708). {ECO:0000269|PubMed:12718872, ECO:0000269|PubMed:15995708, ECO:0000269|PubMed:16807356}.
Interaction partners:
- Nucleoporin SEH1
- Nuclear pore complex protein Nup214
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein Nup133
- Nucleoporin Nup43
- Protein SEC13 homolog
- Nuclear pore complex protein Nup93
- Nuclear pore complex protein Nup160
- Nucleoporin Nup37
- Nuclear pore complex protein Nup107
Sequence:
MEELDGEPTVTLIPGVNSKKNQMYFDWGPGEMLVCETSFNKKEKSEMVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEMHQVAIAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKELLSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS
Protein: Beta-1,2-xylosyltransferase RCN11 (OsXylT) (EC 2.4.2.-) (Protein REDUCED CULM NUMBER 11) (Q6ZFH6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Beta-1,2-linked xylose residues on N-glycans are critical for seed germination and plant development and growth under conditions of abiotic stress.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:26025522}; Single-pass type II membrane protein {ECO:0000305|PubMed:26025522}.
Interaction partners:
- Fucosyltransferase
- Os02g0798100 protein.
- Os02g0646901 protein
- Fucosyltransferase
- Fucosyltransferase
Sequence:
MMPVRTYHHHHHHNNSNNHRLRRIIPRVLLAVFAIYAVSFAAYLLRHQSPHPHPHPAADPERDAVDAAGGGGGGGAVDRVRVEAPSSQKPWPRLPSFLPWTSASVRPPPKHSCEGYFGNGFSRLVDVLPARGGGGGGWFRCHHSETLRSSICEGGRVRLDPGLIAMSRGGEPLDQVMGRAEEEELPKYEPGALQVEAAAKRTGPLVEAGFLDAYVPTGGIGMHTMRSLLDSGRVVPPGELHCSQWVEEPTLLVTRFEYANLFHTITDWYSAYVSSRVTDLPNRPNVVFVDGHCKAQLEQTWEALFSNVTYVKNFSGPVCFRHAILSPLGYETALFKGLSESFSCEGASAESLREKPDHQKTARLSEFGEMILASFDLLRDDILSSKTSNGLNVLFVRREDYLAHPRHSGKVESRLSNEKEVYDAIEGWAKGQKCKINVINGLFAHMNMKEQLRAIQEASVVIGAHGAGLTHLVSATPDTKVLEIISSMYRRPHFALISHWKSLEYHAINLPGSYARVTDVINELSNILKGFGC
Protein: Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6) (Q13247)
Organism: Homo sapiens (Human)
Function: Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
Subcellular location: Nucleus {ECO:0000269|PubMed:12549914, ECO:0000269|PubMed:22767602}. Nucleus speckle {ECO:0000269|PubMed:22767602}.
Interaction partners:
- Serine/arginine-rich splicing factor 3
- SRSF protein kinase 1
- Serine/arginine-rich splicing factor 1
- Transformer-2 protein homolog beta
- Splicing factor U2AF 65 kDa subunit
- Serine/arginine-rich splicing factor 7
- Serine/arginine-rich splicing factor 4
- Serine/arginine-rich splicing factor 9
- Serine/arginine-rich splicing factor 11
- Transformer-2 protein homolog alpha
Sequence:
MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD
Protein: HEAT repeat domain-containing protein (Q55BX9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSDNNNILISECIKESLIEFKEVLEDESTIVYLGGLISESESFEEIKDQFNLFCKDFDMPFKDEDNEIDRVFNQLINLLKRKGCISFSVESKPKSHLVCTNGDKKSVNLEDPNLTMEQYLSLTYSEDSRTRLATLRTMCPCKVKADIDQFYDRIIEMSKDSDRNIRYQAMHNLCDGSPAWREDAVIQTLESMHNDSDPKIRRRIHNILTHYKHTGKWNIM
Protein: RNA-editing complex protein MP42 (Q95W13)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MKRVTSHISRFLPLVLSQRGLSTYASPHVSSMRYYGATKCLLASTPDTPSFQCGECGKAFRLINALNHHIMTKHAGKAKAMMNKGGKLEEVNPEEIKNKPQGAMSQPTSPPPSSSTSGTEAASTSPTHSSFPGIPFSPVGGIGLVGTPVGAASHVVNTTTTAANSASGNALSDENADKKTFVCTICQKTFRLEAALQHHYQAKHNMEMPTSSSSSGGASAQPVLQGGATTAGVGSVGFSHTEEETGRSAMGTQYVHSQETILPQAPQYHLDVAPNAPEEGEVAAHWRCVNHCVMLGVVQNIQEGFVFEDKVLQFTLITDFEGPSPGDPDKDFHTVRVFDSDYSSRVKEQLRDGEWFLVTGRLRMVPQYDGSMRKYYHYPVIQVHPGCGSVLKV
Protein: Exocrine gland secreted peptide 34 (Exocrine gland-secreting peptide 34) (A8R0W6)
Organism: Mus musculus (Mouse)
Interaction partners:
- Predicted gene 12887
Sequence:
MASFPVMCFLLILLLPSMFTEGVVLKKDQEELIDSEDESIILISCQYIQEFLKNAGEILFYSNDKEVMFEKIIDRDFFFFVFV
Protein: Chaperonin GroEL (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin-60) (Cpn60) (O68324)
Organism: Lactobacillus helveticus (Lactobacillus suntoryeus)
Function: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00600}.
Interaction partners:
Sequence:
MAKDIKFSENARRSLLKGVDKLADTVKTTIGPKGRNVVLEQSYGNPDITNDGVTIAKSIELKDRYENMGAKLVAEAAQKTNDIAGDGTTTATVLTQAIAREGMKNVTAGANPVGIRRGIEKATKAAVDELHKISHKVESKDQIANVAAVSSASKEIGALIADAMEKVGHDGVITIEDSRGINTELSVVEGMQFDRGYLSQYMVTDNDKMEADLDNPYILITDKKISNIQDILPLLQEIVQQGKSLLIIADDITGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAQLQDIAALTGGTVITEDLGLELKDTKIDQLGQARRITVTKDSTTIVGGAGSKEAIDERVDTIRKQIEDSTSDFDKKKLQERLAKLTGGVAVIHVGAATETELKERRYRIEDALNSTRAAVDEGYVAGGGTALVNVEKAVREVKGETTDEQTGINIVLRALSAPVRQIAENAGKDGSVILDKLEHQENEIGYNAATDKWENMVDAGIIDPTKVTRTALQNAASIAALLLTTEAVVAEIPEPKQAAPQGGAGAPMGM
Protein: GEO08910p1 (GH03839p) (KAZ1-type serine protease inhibitor-like protein type gamma) (Kaz1-ORFB, isoform A) (Kaz1-ORFB, isoform E) (Kaz1-ORFB, isoform F) (Q7KYD6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDWIKIFVSGLALLLIGMAQCYPQFDSENPWLRPRQPTEPTISPNAGGSTPANAAPPTTQSPRYFACFHSCPATSEYNPICGSDNVNYYNENKFNCALNCGLNIRKVHKGICQT
Protein: Netrin receptor unc-5 (Unc5 netrin receptor) (Q95TU8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Receptor for netrin required for motor axon guidance. Mediates both short- and long-range axon motor repulsion in the developing nervous system upon ligand binding. Also involved in glial migration. While short-range repulsion requires both fra and unc-5, long-range repulsion only requires unc-5.
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Latrophilin Cirl
- Netrin-B
- Netrin-A
- LD45603p
- Division abnormally delayed protein
- Trio, isoform A
- FI21454p1
- Down syndrome cell adhesion molecule 1, isoform BX
- FI24025p1
- Protein slit
Sequence:
MAVINKAGNVIALLLVKLQLILLFTLSVSGELPQLDYGSLSASLEEDAIDPLTAMAPFANSLVTEESAQHKNNAELLGNSSEDENVRPQQGSSSSGLGSSGAAGGSGILLEEFNSGKLSPGEASNTLPIFLIEPESVFVVKNRPAVLKCKASHSLQVIFKCSGSSQPPPSTHETHVDPHTGVNMEEVTATIHRDLVDEFFGDGPFKCECHAWSSRGVVKSQAATVHIAYIRKSFNQSPTSLRLELGSRAELRCEPPGGFPEPKLTWHKNNAVITADSEPGITVSAGTLIFRQVALQHMANYSCSAENIAGRRVSDSAVLIVYVNGGWSTWSPWRECKCAGKPSQGRKRSRTCNNPMPLNGGAQCPGPQIQKSADCAACPEDTQIVSPDGFDISSSKRMARWSAWSDWSICSAECIQVRRRKCLTQGQTQISSEAEEAGDLLLGAPGVGMAALIAAAGVGAVGSPSEATGSSSDIIPGYGKSLCAGKDIQTAECRGEQCQIGKDDFDWTLYLGLAFITAVCFAFGTALICCARRGIRTNPHYNMARSVMDADYMPGVVEKKEMRMHIEASNMGYDYVNPGHRYLPGEHIMGMGIGCGGVTEHHYDVPNLSANYTNPIDHLSVDYLSETGESSTADTSNSTFDMNGKLSILNASKSSTYEMLGSAGGQLRLYGGELLLFVPEHAIGKHVKKHVSLLLLSDECSRVSCATESSILCSSVVHSAPRNYSFVKPVILKIPHCLVAPEQWHVHIYHADSEHDELSVNWRRAVSVGEETINTPMFVQLEATHVFIMTEQLGHFTVVAEPRIQQPSIKMKLLAFSQHTPPSNANCSLRIYVVKDFPNSRDICANVEAKLGGSFLGESQVFAFTLNSRNLNIRVRSADVEAAAPYEHAIPYQHILSNNSILHCEFSLRRQDQNSLCVDFGQGSEDDYYTFNIPAHSMSGSAEELASTTNTTISIDRQGNYVNESCVMDFVQLPHATKRLICGALDPPRADERDWRLLAKKLNTDRYIAYFATKASPTEQILNLWECRANSSPGSSSNSVSHTIMALLLTLKEMGRQDVLDIIVETIGPLWI
Protein: Small RNA 2'-O-methyltransferase (EC 2.1.1.386) (HEN1 methyltransferase homolog 1) (Q230X8)
Organism: Tetrahymena thermophila (strain SB210)
Function: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Required for programmed DNA elimination.
Subcellular location: Nucleus {ECO:0000269|PubMed:19240163}. Note=Localizes to the macronucleus.
Interaction partners:
Sequence:
MIEAYETDVFMDPIGMKVWEKRHQYVATKLSALNCKRVLDMGTNTCKLIQRLSRSLQFTQIDGLDIDGQLLETQGIQNAKPDLIQNQYASMRDHQLVVNLYQGSALNKIQHLKDQQYDAVILVELIEHLQVEDVFLIEQNLFGFLRPQFVIVTTPNSDFNVYFNFKEQGVLFRDKDHKFEWSQNQFQIWAQKVCQNYGYKVIELTGVGEHKTEGTKNGFCTQIVVFEKDTQQEKYLNFAFFNLQEGEIRQVCQILYPFESKEQHFQREVVDSIRYILHITDKQNQFEDGSYQNYTTLSRIMQNHSISSNWQIQGDYFKLKTYIQNISEFLVHENQFNFQESFVTLNYQAQMEDEENEDQLESDSENVKMQQQQYYFSNDNCFSTKDTTYSSFSTADNLFSQKIQLGQQQMALEEIELEDTIDY
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (Q9VIB5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNKNLGFVERLRWRLKTIEHKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQPKDKAVQVQFVFDKVEGSEDCLYLNVYTNNVKPDKARPVMVWIHGGGFIIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAGAPVYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWPKLKVWESLYDDNKDLLF
Protein: Olfactory receptor 1D5 (Olfactory receptor 17-31) (OR17-31) (P58170)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
Sequence:
MDGDNQSENSQFLLLGISESPEQQRILFWMFLSMYLVTVLGNVLIILAISSDSHLHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVATCCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPREIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTPLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLHTYSMKDSVATVMYAVLTPMMNPFIYRLRNKDMHGAPGRVLWRPFQRPK
Protein: NAD(P)H-quinone oxidoreductase subunit T, chloroplastic (EC 7.1.1.-) (DNA J PROTEIN C75) (NAD(P)H dehydrogenase subunit T) (NDH subunit T) (NADH-plastoquinone oxidoreductase subunit T) (Protein CHLORORESPIRATORY REDUCTION J) (Q9SMS0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (Probable). Required for the accumulation of both the NDH subcomplex A and NDHS.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:21505067, ECO:0000269|PubMed:23894646}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- NAD
- NAD
- Photosynthetic NDH subunit of subcomplex B 2, chloroplastic
- NAD
- Transmembrane protein
- RNI-like superfamily protein
- At1g77930
- At2g17880
- Photosynthetic NDH subunit of subcomplex B 1, chloroplastic
- Dihydrodipicolinate reductase-like protein CRR1, chloroplastic
Sequence:
MAYATSTYARTSCIILPKIQNGAHFTDDTKAFRRITARRVTRIYASQGPTKPSKPSPGVDTRIHWESPDEGWIGGRSDPAKSVDEDKTNLLSDEKFAELIKDSFDSHYQFLGVSTDADLEEIKSAYRRLSKEYHPDTTSLPLKTASEKFMKLREVYNVLSDEETRRFYDWTLAQEVASRQAEKMRMKLEDPKEQDFRGYESIPDMVDRLGGRNMELSDQAMTALTFDILIVLFAVCCIAFVIVFKDPSY