wanglab/gogpt-training-data huggingface dataset:
Protein: NPC intracellular cholesterol transporter 1 isoform X2 (Niemann-Pick disease, type C1) (F1QNG7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
Sequence:
MLLLGRNHIFRLLLATVLLSHWVHGQHCIWYGECGNSPNVPEKKLNCNYTGPAVPLPNEGQELLQELCPRLVYADNRVCCDTQQLNTLKSNIQIPLQYLSRCPACFFNFMTLFCELTCSPRQSQFISVKDFLKEKNQTSVGNVTYYITQTFADAMFNACRDVQAPSSNIKALGLLCGRDASVCTPQIWIQYMFSISNGQVPFGIEPIFTDVPVQGMTPMNNRTFNCSQSLDDGSEPCSCQDCSEVCGPTPVPPPIPPPWIILGLDAMSFIMWCSYIAFLLIFFGVVLGAWCYRRSVVTSEYGPILDSNQPHSLNSDGTDLIDEASCCETVGERFENSLRLVFSRWGSLCVRQPLTIILSSLVLICICSAGLSYMRITTNPVELWSAPSSRARQEKNYFDQHFGPFFRTEQLIITTPWTEEGGFSTITGDIIPFSPILNLSLLHQVLDLQLEIENLIAEYKGENVTLKDICVSPLSPYNDNCTILSVLNYFQNSHEVLDHEFQDEFFLYNDYHTHLLYCASSPTSLDDTSRLHDPCMGTFGGPVFPWLVLGGYEDSAYNNATALVITFPVTNYLNDTEKLGKALAWEKEFIRFMKNYENPNLTVSFSSERSIEDEIDRESNSDVSTIVISYIIMFVYISVALGRINSCRTLLVDSKISLGIAGILIVLSSVACSLGIFSYIGIPLTLIVIEVIPFLVLAVGVDNIFIIVQTYQRDERMPEEELHQQIGRILGDVAPSMFLSSFSETVAFFLGALSTMPAVRTFSLFAGLAIFIDFLLQISCFVSLLGLDIKRQEANRMDILCCVKLSDGQEEKSEGWLFRFFKKIYAPFILKDWVRPLVVAVFVGMLSFSIAVVNKVEIGLEQTLSMPDDSYVLNYFGNLSKYLHTGPPVYFVVEDGHDYKTFEGQNAVCGGVGCNNDSLVQQIYTASLMSNYTRISNVPSSWLDDYFDWVKPQSTCCRYYNSTGAFCNASVVDKSCVHCRPMTSSGKQRPNGTEFMHFLPMFLSDNPNIKCGKGGHAAYGTAVDLKDNNTDVGATYFMSYHTILKNSSDFINAMKMARELTDNITQTLSTHDKSYKVFPYSVFYVFYEQYLTIVDDTALNLGVSLSAIFIVTAVLLGFELWSAVLVCFTIAMILINMFGVMWLWSISLNAVSLVNLVMSCGISVEFCSHIVRAFSISTRSSRVERAEEALAHMGSSVFSGITLTKFGGILILALSKSQIFQIFYFRMYLAIVLLGAAHGLIFLPVLLSYAGPSVNKAKVLAAHNRFVGTERERLIY
Protein: Alpha-2,8-sialyltransferase ST8Sia III (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3) (Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase) (B0CN48)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323}.
Interaction partners:
Sequence:
MVRVVSVLGLVMFSVALLILSLISYVSIKKDFIFTAPKYANAGGPRMYMFHAGFRSQLAMKFLDPAFTSLNTALNENLQESSNWRFNRSAYAELSKEIAQHIDVPHNFTLTKNSVRVGQLMHYDYSSHKYVFSIGENLRSLLPDASPVLNKRYNTCAVVGNSGILTGSRCGPEIDKYDFVFRCNFAPTEVFRRDVGRRTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHKGQLKVQLAWPGNIMQYVNRYWKTKQLSPKRLSTGILMFTLASSLCEQVHLYGFWPFGWDPNTGKELPYHYYDKKGTKFTTKWQESHQLPTEFKLLFKMHADGVLKLSLSHCA
Protein: Delta-6 fatty acyl desaturase (Q4TVM9)
Organism: Gadus morhua (Atlantic cod)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGGGGQLTEPVETSACGGRAASVYTWDEVQKHCHRNDQWLVINRKVYNVTQWAKRHPGGLRVISHYAGEDATEAFLAFHPNPKLVQKFLKPLLIGELAVTEPSQDRNKNAAVVEDFQALRTRAEGLGLFQAQPLFFCLHLGHILLLELLAWMSVWLWGTGWRTTLLCSFILAVAQAQAGWLQHDFGHLSVFKLSRWNHIFHKFIIGHLKGASGNWWNHRHFQHHAKPNVFSKDPDVNMLHVFVVGDIQPVEYGIKKIKYMPYHHQHQYFFLVGPPLLIPVYFHIQILRAMFSRRDWVDLAWSMSYYLRYFCCYAPFYGLLGSVALISFVRFLESHWFVWVTQMNHLPMNIDHEKQQDWLSMQLSATCNIEQSCFNDWFSGHLNFQIEHHLFPTMPRHNYQVLAPLVRALCEKHSIPYQEKTLWRGVADVVRSLKNSGDLWMDAYLHK
Protein: Adenosine transporter 2, putative (Q586N1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Amino acid transporter 10, putative
- Amino acid transporter, putative
Sequence:
MAMLGFESTAEFFAYLTFMFFGMSVMNVTNAIYSNYNFFSQYYKFAQGDADAVSKNTSFWEHMFTYYNVVVFTMQVLLETFMLTPLGRQIPVTWRYVFGLTIPMVEIIVILVIPAVGGTSEGGAMATMMIVAFVDGISKTLCDSSNAVTTGPFPTKFYSAMVMGLAVSGIMTSFLSIVIKASMKDNFESRRTQSQIYFGLVMLSQVVACVLLFLLRKNPYAIKYAAEFRYAARKKGTVCDFDVKGTGPVSGNRYADEKENKNVLNADIDPDDMRDTDQVEGTTNAQQMLDASIMVVVKRIWPVLLSCFFVFFATLLVFPGVFLAVRDSLTIKDFWYFNIVVAMFNLGDFSSRFALQFKRLHVSPRMVMIGSFARALLIIPLALCVPGTIPGVWLPCILCLLWGFTNGYFGGLSMIYGPRNGSLTTAGQRSLAAVCINVSLLMGLFAGAMFALAVKEALPKTE
Protein: Intraflagellar transport protein 172 homolog (Selective LIM-binding factor) (Q9JKU3)
Organism: Rattus norvegicus (Rat)
Function: Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway (By similarity).
Subcellular location: Cell projection, cilium {ECO:0000250}. Nucleus {ECO:0000269|PubMed:10788441}.
Interaction partners:
- Intraflagellar transport protein 80 homolog
- Intraflagellar transport protein 57 homolog
- TRAF3-interacting protein 1
- Intraflagellar transport 88
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport 52
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 56
- Intraflagellar transport protein 27 homolog
- Intraflagellar transport protein 22 homolog
Sequence:
MQLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYIIVFGLAEGKVRLANTKTNKSSTIYGTDSYVVALTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRRIVAYGKEGHVLQTFDYSRDPQEREFTTAAASPGGQSVVLGSYDRLRVFNWSPRRSIWEEAKPKEIANLYTVTALAWKRDGSRLCAGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQLIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSDTLLLGDLNTNRLSEIPWQGSGGNEKYFFENENVCMIFNAGELTLVEYGSNDSLGSVRTEFMNPHLISVRINERCQRGMEDNKKLAYLVDIKTIAIVDLIGGYNIGTISHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYVQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMSSIRGDVVGLERGGGKTEVMVTEGVTTVAYTLDEGLIEFGTAIDDGNYTRATAFLETLEMTPETEAMWKTLSKLALEARQLHTAERCFSALGHVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMDMYQELHRWDECIAVAEAKGHPALEKLRRDYYQRLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITTALIKGELYERAGDLFEKIRNPQRALECYCKGNAFMKAVELARLAFPVEVVRLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPRVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVEEPDLAITMFKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELETEGRLQEAEYHYLEAQEWKATVNMYRSSGLWEEAYRVAKAHGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAIDHAADNCSFEFAFELSRLALKHKTPEIHLRYAMYLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPGQLEALQEEYEREATKKGGRGVEGLVEQARQWEQAGEYSRAVDCYLKVRDSGSSGLMEKCWMKAAELSIKFLPPQRSLEVVRVVGPQLIGIGKHSASAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVVAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGGYAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNNAEAYHSWADLRDVLFNLCENLVKSSEANSAAHEEFEMMLLIAHYYATRSAAQSIKQLETVAARLSVSLLRHTQLLPADKAFYEAGTAAKEVGWENMAFIFFNRFLDLTDAIEEGTLDALDHSDFQDTDIPFEVPLPAKQHVPEAQREEVRDWVLTVSMDQRLEQVLPRDERGVYEASLVAASTGVRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ
Protein: ATM interactor (ATM/ATR-substrate CHK2-interacting zinc finger protein) (ASCIZ) (Q6P9S1)
Organism: Mus musculus (Mouse)
Function: Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM (By similarity). Binds to the DYNLL1 promoter and activates its transcription.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O43313}. Note=Nuclear, in discrete foci during G1 phase. {ECO:0000250|UniProtKB:O43313}.
Interaction partners:
- Serine-protein kinase ATM
- E3 ubiquitin-protein ligase UBR5
- Dynein light chain 1, cytoplasmic
- ATPase WRNIP1
Sequence:
MAATEAAAADSAGPAPGVPATPASTRGAAAASSPWRPPESRLQGSRPRPARARAAAPVPPARELIQPTVSELSRAVRTNILCTVRGCGKILPNSPALNMHLVKSHRLQDGIVNPTIRKDLTTAPKFYCCPIKGCPRGPDRPFSQFSLVKQHFMKMHAEKKHKCSKCSNSYGTEWDLKRHEEDCGKTFQCTCGCPYASRTALQSHIYRTGHEIPAEHRDPPSKKRKMESYLQNQKLSSKTTEPLSDQAAPRQDAAEPDAPEVKPAASLEDSCSAHTKKQSVATPPRCPQKLLLPKPKVALVKLPVMQFSPVPVFVPTAESSAQPVVLGVDHSSAAGTVHLVPLSVGALILSLDSEACSLKESLPLSKIISPVVEPMNTGVQVNLGKSLCSPLQEVGSVCQRTSISSSNVQTDLTYASANLIPSAQWLGPDSSVSSCSQTDLSFDSQVSLPVSVHTQTLVPSSKVTSSIAAQTDAFIDACFQPGGVSRETQTSRMQNRTNDSVPVGHTGLCGDIFESVHASYSVPTDTIMSSSLVAETGTHGLPPQSDPKILGQVMEKSAPVLNFSTQNGLLPAHTMTDNQTQTIDLLSDLENILSSNLPGQTLDNRSLLSDTNPGPDAQLPAGSAQNSGIDFDIEEFLSASNIQTQTEESELSSMSTEPVLESLDIETQTDVLLSDPSTQPYGFRAGSGFLGLEMFDTQTQTDLNFFLDSSPHLPLGSILKHSSFSMSTDSSDTETQTEGACPARHLPALESKVQLSSTETQTMSSGFEPLGNLFLTSNETQTAMDDFLLADLAWNTMESQFSSVETQTCAELHAVSSF
Protein: Testis-specific basic protein Y 1 (Basic charge, Y-linked 1) (Variably charged protein Y) (O14598)
Organism: Homo sapiens (Human)
Function: May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
Interaction partners:
- Testis-specific basic protein Y 2
- Testis-specific chromodomain protein Y 2
- Testis-specific chromodomain protein Y 1
- PTPN13-like protein, Y-linked
- Testis-specific Y-encoded protein 1
- Deleted in azoospermia protein 1
- Heat shock transcription factor, Y-linked
- Deleted in azoospermia protein 2
- RNA-binding motif protein, Y chromosome, family 1 member A1
Sequence:
MSPKPRASGPPAKAKETGKRKSSSQPSPSGPKKKTTKVAEKGEAVRGGRRGKKGAATKMAAVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSKGRPSTPLSP
Protein: Cyclic nucleotide-binding domain-containing protein (Q57XP2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSIVNQLTPAERRILNEALENAEKRACNGALAAAEGTQFPLIPGVATAGARRAKPKACNTMERISQQERQERELWMAVERSLEHPFVYRTDSSKELAVNMLRRIPRLKDLSLRDLETMSSTMRIAHVGDGVVLAGNQPRKTEANVETMDYIDRYSLVVNEDTATTAGWSSDVDLAPKAEREVTSAQEASEQGRDDSSCSPSKSSARHDMARYVYVLLRGNVLLRLPFKCPMDALVEPYEMFGLPTTLAALPEDAYYQTCSDCVLLCFPRNKEYVMDGVLKRLDKRLVQEQTTFLQQHLRVKVLTHWTPQEYERCARALVPLRVSWRQMVVEQDMESDAMYFIKEGQCVVVRNVPLPRGRARYGRRVHEGSVTCFPSTGAKARQSRQLNESVTSFGHFPSSVPRGQQHNLPSQTMKFVEVATLREGEFFGELGLLSHEVDRKPDVEKIRSEAYWRNTLAAAKDAPTDYAPLDGELPLQKVLQPLSSGSPSPRGIEGDPTSFALGLEPTNKFSMFPQPTMGRQASVYTRCPCVFYMLPYDRCRELFGAREYAQLKEFANGYPSREDIEIHYERQRKWSKYRKTLVNDVLNDASNMRQKSHEGCSRVK
Protein: Suppressor of HU sensitivity involved in recombination protein 1 (P38751)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.
Subcellular location: Nucleus {ECO:0000269|PubMed:15654096}.
Interaction partners:
- Chromosome segregation in meiosis protein 2
- Platinum sensitivity protein 3
- Suppressor of hydroxyurea sensitivity protein 2
- DNA repair protein RAD2
- ATP-dependent helicase SGS1
- DNA repair protein RAD4
- Elongin-C
- ARS-binding factor 1
- General transcription and DNA repair factor IIH subunit TFB1
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2
Sequence:
MQFEERLQQLVESDWSLDQSSPNVLVIVLGDTARKYVELGGLKEHVTTNTVAGHVASRERVSVVFLGRVKYLYMYLTRMQAQANGPQYSNVLVYGLWDLTATQDGPQQLRLLSLVLRQCLSLPSKVEFYPEPPSSSVPARLLRFWDHIIR
Protein: Spermatogenesis-defective protein 39 homolog (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction) (Q6IA61)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00004541}. Early endosome {ECO:0000256|ARBA:ARBA00004412}. Late endosome {ECO:0000256|ARBA:ARBA00004603}.
Interaction partners:
Sequence:
MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDDDDLERVSWSGEPVGSISWSIRETAGNSGSTHEGREQLKSRNSFSSYAQLPKPTSTYSLSSFFRGRTRPGSFQSLSDALSDTPAKSYAPELGRPKGEYRDYSNDWSPSDTVRRLRKGKVCSLERFRSLQDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPDKRKEFLKTCVGLPFSAEDSAHIQDHYTLLERQIIIEANDRHLESAGQTEIFRKHPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPVNLKKTFKIPDKQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNNAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTYRDLKDRQQLLAYRSKVDKGSAEEEKIDALLSSSQIRWKN
Protein: Pre-mRNA-splicing factor CWC22 homolog (Lethal protein 858) (Nucampholin) (Q17336)
Organism: Caenorhabditis elegans
Function: Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay (By similarity). Plays a role in the nuclear retention of unspliced mRNAs. Plays a role in sex determination. Required for early embryogenesis and tissue differentiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:9136012}. Nucleus speckle {ECO:0000250}.
Interaction partners:
- Protein BUD31 homolog
- Cell division cycle 5-like protein
- Pre-mRNA-splicing factor SLU7
- RNA helicase
- Tr-type G domain-containing protein
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1
- Splicing factor YJU2
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- Pre-mRNA-splicing factor CWC25 homolog
- Protein FAM32A
Sequence:
MSSSRSQSPETPKAASEEREEEEKESSEQPDTPKTSSEKSASRSQSPRESREVSQETETSENQEKIKEKDDGDDQPGTPNSYRSRETSPAPKRSKETRESESPEKSPVRSRSPRRSSARSPSRSPRRRRERSSERKQSEEPAPLPEKKKKEPLDILRTRTGGAYIPPAKLRLMQQQISDKQSEQYQRMNWERMKKKIHGLVNRVNAKNLVQIVRELLQENVIRSKGLLCRDIIQAQAFSPGFSNVYAALAAVINSKFPHVGELLLRRLIVQFKRSFRRNDRGVTVNVIKFIAHLINQQVAHEVLALEIMILMLEEPTDDSVEVAIAFLKECGAKLLEIAPAALNSVYDRLRAILMETERSENALDRRIQYMIETAMQIRKDKFAAYPAVIEDLDLIEEEDQIIHTLNLEDAVDPENGLNVFKLDPEFEKNEEVYEEIRKEIIGNADISDEDGGDELDDEEEGSDVEEAPKKTTEIIDNTDQNLTAFRREVYLTMQSSLDYQEAAHKLLKMKIPDSMQNELCAMLVDCCAQQRTYERFYGMLIERFCRLRLEYQQYFEKLCQDTYSTIHRIDITKLRNLARLIAHLLSTDAIDWKILADMKMTEEDTTSSGRIYIKYIFNELVEAMGMVKLHSRVTDPTLAHCFVGLFPRTNPNSARFSINFFTMIGLGGLTLELREWLAKGLKKKKGMLDQLKAESSSDSSSSSDSSDSSDSSDSDDSSDSSSDSSSSSESEPEPPKKKKKKNSEESSKKKEKENIGRRDRGDKRAERHRDQSVENKDKDRRRRQDSDENRRPERGDDRKDRSKDRRRQDSDDEDRKGRERREDSGERRRGDRDRRDRNKDQEDHREDRRDRSKDREDRRDRRRHDSDDDRKTRRDRSEERGGRRREVESDDRRRRR
Protein: Alba DNA/RNA-binding protein (F4JD88)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDRYQRVAKPKPESPINENEIRITSKGLIRNYISYATSLLQEKSVKDIVLKAMGQAISKTVAISEILKNKIPGLHQDIAISSISITDVWEPTEEGLFPVELTRHVSMISITLSLSELNKDSPGYQAPAQSDQSKPQYQPQQGRQARLPYNAYGEEGEVVAEGEAGEEVDMETTKGVMKEKTKGTIKKIIKTMKVGIQTRAEAVDVVDEAMAIVGGRGGYGGGRDGGYGGGRDDGYGERRNDGYGERRNDRYGGGRDDGYGGGRDDGYGGGRNDGYGGRRGGFRGGRGGGRDEGYGGGRGGYGGRSGGQGDGYGGGRGDGYGGGRGDGYGGGRGDGYGGGRVDRYDGGRRDGYGGGRYDGYGGGKSDGYGGGRGGYRGGRGGYGRGRGRMGNGGRSRDGASNQNEA
Protein: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C) (Q969Q6)
Organism: Homo sapiens (Human)
Function: May regulate MCM3AP phosphorylation through phosphatase recruitment (By similarity). May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:15820313}. Cytoplasm {ECO:0000269|PubMed:15820313}. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis. {ECO:0000269|PubMed:15820313}.
Interaction partners:
- Inter-alpha-trypsin inhibitor heavy chain H4
- Apoptosis regulator Bcl-2
- Troponin I, cardiac muscle
- D
- Protein phosphatase 1 regulatory subunit 1A
- Ryanodine receptor 2
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Centrosomal protein 43
- Beta-arrestin-1
- Beta-arrestin-2
Sequence:
MDWKEVLRRRLATPNTCPNKKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQTPPMIGEEAMINYENFLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDSENSADLDDT
Protein: O-fucosyltransferase 23 (O-FucT-23) (EC 2.4.1.-) (O-fucosyltransferase 1) (AtOFT1) (O-fucosyltransferase family protein) (Q9MA87)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable protein O-fucosyltransferase required for correct pollen tube penetration through the stigma-style interface. May be involved in protein O-glycosylation events during pollen-pistil interactions.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:29467178}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Cyclin-dependent kinase E-1
- Mediator of RNA polymerase II transcription subunit 23
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 6
- O-fucosyltransferase 36
- O-fucosyltransferase 5
- O-fucosyltransferase 14
- Cyclin-C1-1
- Cyclin-C1-2
Sequence:
MNSPLSSKNLRIFSKSVACKCLVLVGIALFYRALLLSYSPRNALSNSLLFRDRHMSDSSSTGGIRTDKFLEVPQIVWGLNNQKIAFARACLTARMMNRTLLMPSLSASLFYKEVDKLRPIPFDKVFQFERFNSLCSGFVRLSRFSDVKNRAQVFDLEKGSGRRWTVERDLEHLKQSARNESIDEFEVIRLIGKNPFLWHDHWPVEDYAKVFECMVVVDEISREADKVVMKIREAGEAERAKLASKTEILGPVPFVAVHMRIEIDWMIHCKKLEQRKKISEICSSKREILDRVGNISGLKTPTVLYLAVADTLLEEKEEDSSVLSGWRDGLIPFEKKKLGVKEEIYGKYSYLIQSAIDYEVCLRADVFVGNSFSTFSSLIVLERTQKARRLGFMSSCKDGGNKWRSYAYNLAGESNGVPRRWMTNMTHSSLQAISYGSNSVSCSSG
Protein: RAS protein activator like 2 (D3YUS5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MFTGLESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVFDVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQLVLLNKEKEMPVEGQDQQTDSTKGRCLRRTVSVPSEGQFPEYPQEGTTKLEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNADDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCSSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFITSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELMDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFAEHSSSPNVSGSLSSGLQRICEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKENSLPNGRSISLMDLQDTHAAQAEHASVMLDVPMRLAGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLNNPVPAMPKASADSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSSHSEDFSRRHTVPDRHIPLALPRQNSTGQSQIRKLDHSGLGARAKAPPSLPHSASLRSTGSMSVASAALMAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC
Protein: NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (EC 2.3.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (NAD-dependent protein biotinylase sirtuin-4) (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-4) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4) (G3V641)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion matrix {ECO:0000256|HAMAP-Rule:MF_03161}.
Interaction partners:
- Sirtuin 6 6
- NAD-dependent protein deacetylase
- NAD-dependent protein deacetylase sirtuin-2
- NAD-dependent protein deacylase sirtuin-5, mitochondrial
- NAD-dependent protein deacetylase sirtuin-1
- Nicotinamide phosphoribosyltransferase
- NAD-dependent protein deacetylase sirtuin-7
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
- Nicotinamide-nucleotide adenylyltransferase
- Glutamine-dependent NAD
Sequence:
MRGLIFRPTRGRWITQMSQLRSHGSTGLFVPPSPPLDHEKIKELQRFISLSKKLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHIDFIRSAPVRQRYWARNFVGWPQFSSHQPNPAHWALSNWEKLGKLHWLVTQNVDALHSKAGNQRLTELHGCMHRVLCLSCGEQTARRVLQDRFQALNPSWSAEAQGVAPDGDVFLTEEQVRSFRVPCCDRCGGPLKPDVVFFGDTVNPDKVDFVHQRVKEADSLLVVGSSLQVYSGYRFILTAREKKLPIAILNIGPTRSDDLACLKLDSRCGELLPLIDPQ
Protein: Jonah 74E (EC 3.4.21.-) (M9MS20)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Trypsin epsilon
- Trypsin alpha
- Trypsin beta
- Aminopeptidase
- Jonah 25Biii
- Zinc carboxypeptidase A 1
- Jonah 25Bii, isoform A
- Peptidase S1 domain-containing protein
- Jonah 65Aiv
- Aminopeptidase
Sequence:
MQISTILVFLLILVQGRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSYANIKPTNICMDTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTRITAYLDWIGEVSGVHYP
Protein: Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58) (Q62902)
Organism: Rattus norvegicus (Rat)
Function: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins (By similarity).
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Multiple coagulation factor deficiency protein 2 homolog
- Vesicle-trafficking protein SEC22b
- Protein transport protein Sec31A
- Protein SEC13 homolog
- SEC24 homolog C, COPII coat complex component
- Coatomer subunit beta
- SEC24 homolog D, COPII coat complex component
- Protein transport protein SEC23
- SEC24 homolog A, COPII coat complex component
- Golgi reassembly-stacking protein 1
Sequence:
MAVSRRRGPQAGAQSFFCALLLSFSQFVGSDGMGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSADQIRIAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYTENQGLDGPVFGSADMWNGVGIFFDSFDNDGKKNNPAIVVVGNNGQINYDHQNDGATQALASCQRDFRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPADDIFESIGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISRRGAGTPGQPGQVSQQELDTVVRTQLEILRQVNEMKNSMRETMRLVSGVQHPGSAGVYETTQHFMDIKEHLHIVKRDIDSLAQRSMSSNEKPKCPDLPAFPSCLSTVHFVIFIVVQTVLFIGYIMYRTQQEAAAKKFF
Protein: F-box/kelch-repeat protein At2g24250 (Q9ZUH0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F-box/LRR-repeat protein At1g67190
- F-box protein At5g52880
- F-box/kelch-repeat protein At3g24760
- Putative F-box protein At1g47730
- F-box protein At4g27050
- F-box protein At1g30790
- F-box/kelch-repeat protein At3g04660
- F-box/LRR-repeat protein At3g03360
- F-box protein SKIP19
- F-box/kelch-repeat protein At1g23390
Sequence:
MAMKKKISTSSIMPDWSQLPEELLHIISTHLEDHYFDAVHARSVCRSWRSTFPFPSSLLRQSYSLPAFPLESKDLCCTLEKVPLFLFRVLTPPDAADASSEYFLGGLGQDKSNDHVELPSPLQCSVKVNVPGTEPILMNMLDCQIIPLGHKYRLMIGCNPEEYSAAFLPLNEQGGGGEFVALLDCTDLFLVLRSTEMRWIRLEKPSTASCKELFTFRGRFYATFFNGDTFVIDPSSLEATPLTPHIDSNFLVPSGNEELFLVKTDFLRCRVSRLDEEAAEWVEVSDLGDRVLFLGGHLGNFYCSAKELPHGCGLTGDSILFTVGSRNVTYPYKYGVHTNKRKAEDNINCWRSSRENRVLFRNRYDPVLSFRVER
Protein: Glyceraldehyde-3-phosphate dehydrogenase 2 (GAPDH 2) (EC 1.2.1.12) (Q6FSM4)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Phosphoglycerate kinase
- Triosephosphate isomerase
- Fructose-bisphosphate aldolase
- Transketolase
- Glucose-6-phosphate isomerase
- Transaldolase
- Transaldolase
- Glucose-6-phosphate 1-dehydrogenase
- Glyceraldehyde-3-phosphate dehydrogenase 1
- Enolase 1
Sequence:
MVRIAINGFGRIGRLVLRVALSRSNIEVVAVNDPFITTDYAAYMFKYDSTHGRYAGEVTHDDKHIIIDGKKIAVHQERDPANLPWGSENIDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVVGVNEDKYTSDLKIVSNASCTTNCLAPLAKVIDEAFGIEEGLMTTVHSLTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPQLQGKLTGMAFRVPTVDVSVVDLTVKLQKETTYDEIKKVIKQASEGKLKGVLGYTEDAVVSSDFLGDSRSSIFDASAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKN