wanglab/gogpt-training-data huggingface dataset:
Protein: Plastin-1 (Intestine-specific plastin) (I-plastin) (Q14651)
Organism: Homo sapiens (Human)
Function: Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q3V0K9}. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q3V0K9}.
Interaction partners:
- Ezrin
- Fascin-2
- Radixin
- Myosin-9
- Chloride intracellular channel protein 5
- Moesin
- Xin actin-binding repeat-containing protein 2
- Unconventional myosin-VIIa
- Twinfilin-1
- F-actin-capping protein subunit beta
Sequence:
MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRAYFHLLNQIAPKGGEDGPAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNRIK
Protein: Perforin-like protein 2 (Q8I5P0)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MNILLKYHLSYIFFFVHLIVINIKCKEINNNLVNDEKDSINNLEEPSPFHILKKKNSNNIENHSNKINNIFKNNYSYSYSYSLLDNSLYDNKYESDFFPQKKNNKINEEKYKGTHGTNFAIINEHMNEIHNDMLGQNEILSNELDTTKDIIKEEHVKNKKIKNHSFYMNKENEKKKFLDNTFPENKENNKNKRNSKFIEENDLNSSGENYFENDKFIEIEYPIKNKDIDEYEEGINRNHKEEDNKNRTYHSNGEDSIKSLNFIKYMNMDKEKKGKKKSYNRKKKENYNNDNYNINDSDLINVLKQGDYSPDCDTCNKNINGHMNKGRGIRRRMYDRNYYKDFNLRDALPINKTHYSMLLKSDDDTIIKEKNENDVDDIITKEKRKENLKEVYNDKKNNYLSLKYLGLGYDIIMGNPEGDPTLNVDPGFRGPVLQINLKEISLNSYDNHKNDDNHMNDDIHKNDDNHMNSDNHKNDEYHKNDEYHKNDEDHNDDNYDNHADGDKRSKERKSKIQTTNESMKPWVIPEHSCSQSKNVEEIRNLEQYKLELLSDVKVSTPSSFPYSFSASAEFKNALKKLKVQNNVIFLMKIYCLRYYTGIPITTTSYKFSENFKNALSKLPKYFDGLREDSKCSYEYYINKLNSPECEENVNKWMLFFKLHGTHVAYEIYLGGKIIIKININKEEYNKMKENNINVKTFFNIYFHKMGLSSAFQKEAQKILNKFRISKHIAILGGNPGLNVNNTSFFEKWVHSINTNSMPIRTKLLPFSFFMDDNDMIQAYKDALIFYGLTYGLQLFGQEKYNHNIISVGEYLEKCTQKLYAGPPPGLLTCPIGTTILMGFSINLNFYKNKYLSSTNGITLCEPMKESCSGNGFEKNYSDIRIFALCTNKPFDFITQVVQQGEAPKISASCPGELVILFGFALMKGIGSSSANKIDIYPCRTGQNSCEAVLQNHKFKQSMIYLACVDKTTNGLEYLQTYSKTKNLGDVISDKYKSDGYLNFSCPQNNTLVFGFSLEFHTNFQATRNNFLNCSKYTNICEISGIGINTHLSFFRSDKHSLAIIALCRSHGANNLVE
Protein: Cutinase 1 (EC 3.1.1.74) (Cutin hydrolase 1) (P86010)
Organism: Colletotrichum kahawae (Coffee berry disease fungus)
Function: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:17043825}.
Interaction partners:
Sequence:
VIYIFAR
Protein: Cytoplasmic envelopment protein 1 (F5HA10)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04038}. Virion tegument {ECO:0000255|HAMAP-Rule:MF_04038}. Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04038, ECO:0000269|PubMed:21345947}. Host Golgi apparatus {ECO:0000255|HAMAP-Rule:MF_04038, ECO:0000269|PubMed:21345947}.
Interaction partners:
Sequence:
MEALMIRGVLEVHTDFTRQNVMIMEPQVLDFTVRGDKLWLHTEHGLLVSMAEYRSELLCTSAFLGYSAVFLLETEDAVTQVRLSDLRLKHRCGIVKADNLLHFALCTVISCVENCNLTRKCLHDLLQYLDAVNVRESFGRLLHHSARRLICSALYLLFEEKEPHIVQYVPATFVLFQQTRHTCLQLVARFFFRLTGQDEAHSFSLKLTERKTVDGWPVGLGLLDVLNANYPNLPSPPKLPPRWERGEEE
Protein: Pentacotripeptide-repeat region of PRORP domain-containing protein (Q381Z3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMSAKLGINLKGPAEVFIKHPDGSETRVIRRKKGVVQQRNDVDLLNRDEEREMVYACPPYTASFNAMLKERKEKNSRALVNAVLERMHAESIPLNVITYNSLLERVVGASDDIAFELYDEIREDSMCVNSNVQPDLTTYQLLFRACERKSQYHRAFHLYMQMREMPHIVPDTTTYDTLLGFCAAVKDVPQALFFMEEMKKNCVAPSVNTYNCLMGALREKAPYEETLRVYNGMTEWGVKPTVRTFNTVTGAALIHDDYEMAFQLFEEMKKQGVLPNVVSYNTLLCLVRQRLDYVMGRNAYASVKRTREQQAHGMKAISELTTTLFHEMGSMVVEPNTFTFNLVMEILIECDDFGVFDIYRMMQEHYNKNNNKTSIIEEKIEATRMSVSIMMAEASLSLDSNKIQPRERNPSIDSILCSIDVNKDTSNAANLAGLPSLDVIMGMDNRKRSARITANEMQPNVDTYRLIVRACLHFGFAKHCHYFYNAMLNEGLGPDYNFALLMETVCEEIRDVEKAFAVLSHAKMAGVYIDVSLFNAYLRVLAAVGDDKLLSILGEMELGINSFCSQPDVETYNIVLRYHLGLKHYDAVVELFDSMYDSYRQVRPNADTYLWMLQTHRAMNDAEAATQLLESMHKRQIPVDIQHYHELMRVYVQAGDERLLQVFQQLQNGDDGEYQYPKVDVICFSLVMEYYVRLKEWDKLDALFHKLLGYPDMEADVNCYNIMFDMCLLCGKYVEAKSLFNELRMKCVKPDLRMYNTLLHIFAAAADSAMYEVLETMRMNHVAPEASTLSILLQYAEGRHLVSDAVARNLFWDPTTDLKGLL
Protein: RNA helicase (EC 3.6.4.13) (F6WLT2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQ
Protein: Protein TPR1 (Aberrant spikelet and panicle1-related 2) (Protein ASP1-RELATED 2) (OsASPR2) (Topless-related protein 1) (Topless-related protein 2) (OsTPR2) (Q5NBT9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable downstream regulator of strigolactones signaling.
Interaction partners:
- Protein DWARF 53
- Os03g0207900 protein
- Os06g0255200 protein
- Nuclear pore complex protein
Sequence:
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCTPPNGARASPVSVPLAAVPKAGGTYPPLTAHTPFQPPPAGPSLAGWMANAAAATSSVPSAVVAASSLPVPPNQAVPIMKRPTITDYQSAESEQLMKRLRPSGHGVDEATYPAPIPQPLWSVEDLPRTVACTLSQGSSVTSMDFHPTRHTLLLVGSTNGEITLWEVGMRERLFSKPFKIWDIQACSPQFQSVAKESSISINRVTWSPDGDLIGVAFAKHLIHLHAYQQPNETRQVLEIDAHSGAVNDIAFSRPNKQLCVVTCGDDRLIKVWDMHGQKLFSFEGHEAPVYSICPHHKESIQFIFSTSLDGKIKAWLYDHMGSRVDYDAPGKWCTTMLYSADGTRLFSCGTSKDGDSYLVEWNESEGSIKRTYSGFRKKSAGVGVVQFDTAQNHILAAGEDNQIKFWDVDNTTMLSSTEADGGLPGLPRLRFNKEGNLLAVTTVDNGFKILANADGLRTLRAFGNRPFEAFRSQYEASSMKVSGAPVVAGISPNIGRMDHIDRNSPAKPSPIMNGGDPASRSIDIKPRISEERPDKAKPWELMEVLNAQQCRVATMPETPDQASKVVRLLYTNSGVGLLALGSNAIQRLWKWARNDQNPSGKATANVVPQHWQPNSGLVMQNDTADTNPEDAVPCIALSKNDSYVMSACGGKVSLFNMMTFKVMTTFMPPPPASTFLAFHPQDNNIIAIGMEDSTIHIYNVRVDEVKTRLKGHQRRITGLAFSNNLQILVSSGADAQLCVWATDTWEKKKSVAIQMPAGKTPSGDTWVQFNSDWSRLLVVHETQLAIYDASKMERIYQWIPQDALSAPISHASYSRNSQLVFAAFTDGNIGIFDVENLRLRCRIAPPAYLSSAAINSNPSVYPLVVAAHPQESNQFAVGLSDGSVKVIEPLESEGKWGTTPPTENGVPNGRTSTSSATSNPAADQIQR
Protein: Transmembrane protease serine 12 (EC 3.4.21.-) (Q3V0Q7)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q86WS5}; Single-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:32529245, ECO:0000269|PubMed:35547804}. Note=Expression in the acrosome decreases after acrosome reaction. {ECO:0000269|PubMed:32529245}.
Interaction partners:
Sequence:
MASWALSAALLCLGGAFAYSELHSLSLREGSALGQATVPGPPEEEQPVTKDCGIAPLRGAVEGSRIIGGSQADTGAWPWQVSLQVQDGDILMHVCGGALVRDRWVLTAAHCTKEARDPLKWRAVMGTNDLTRSPYHSRNIRITDIIIPPDFIMETFVNDIALFRLKRAVRYNDYIQPICLPFGVFQKLDQNTACFISGWGRTREEGNGTTILQEAKVHFISREVCSSDQGYSGMIPNTSFCAGHENGTFDSCRGDSGGPLMCYLPEHSRYFVMGITSYGHGCGRRHFPGVYSNPSFFQEWMTHYLSQGNINRLFNMDIVLGQVLTALGSVILLGVT
Protein: Outer membrane lipoprotein SlyB (P0A905)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
- Outer membrane protein assembly factor BamA
- Outer membrane protein A
- Uncharacterized protein YqjD
- Protein ElaB
Sequence:
MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGTIVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGGGTGRSLATAAGAVAGGVAGQGVQSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR
Protein: Protein NRDE2 homolog (O42975)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized helicase C17H9.02
- Uncharacterized protein C17A2.08c
- Protein phosphatase PP2A regulatory subunit B
- Uncharacterized protein C140.04
- Cell division control protein 16
- Septum-promoting GTP-binding protein 1
- Uncharacterized protein C20H4.06c
- Serine/threonine-protein kinase plo1
- ATP-dependent RNA helicase mtr4
- G-patch domain-containing protein C1486.03
Sequence:
MPSNHNTSVPKFSSFNSVKAKKNPITKSNKKYRSSHDQVSSNHAKSSFPSHRSIQSNFAVDTKGEKQNLLYGINKRPVPKYHRSSSSVYGSAPLLRIVKESKEGITLNKKKSLEIKYDEERSFDEKENDESEFEDGQQGFIPLLVNRNSDPSEKSTFSLNILKAIKETDEEIKKNPGKARLWIKMCEYQERLLFDEFRRSNSDDIKGKLKIENNSRSVKLSILEKALKEVKGCDHEILVSYYLQLGSEEWSKEETNQKFEEVLIEHPGYLNLWMKYAEYFTGISEFTFNDCLNMFSKCFKFLKQKLSDRKSCKERESTDVTSNFEVEEAILHLLIRLCDFLKNCGYYELAWSIFQANMELCYFYPRYLEKKLDSTFFESFSKFWNSDTPKFSEENARGWCNVLDDESSQQNQNFSSEIGIFQTVKLWYLNESKFDTNPPPRSTMSCRKLSGIDDPFRYIVFNDIQDFIVCFESETIAFAFKYKFFAFCGVPLFPPGISTNSWFASYDKGIYNLLFGMASSESFINGQIAEKNSFQFPCSILPSYIDLFISLMSFKNLNFKLFDYNLAHHVKESMERAFHQLVFSADDEYLASVYLIYLKQMETKNLSEEKPQVNKIVKKILKKYDSSVSVWNTYAQLEHLSGAFTMAETIFKTIFQIHASQLRYIDNLNVYKNWAFRKLLINDTEGCLVIIKCLLFPGDKSLTSDNNRASEMLFGMLENCASKEELLYVCLIYTIWTHCTDMDSMDNCVYLCIQKFESYGWGASSEMECYFSYCSLIFYYQATTLQFYNLPKVRPFFEKGVTLFSANTAIWEVYIFFESKLRQENKPKIRAMKILKSASNAVVTACWYLFYVAVQQIEPTNSQYFLRTLDITLNNEKLKSVAKFWRIYLKILNLRLNGTEWVSAITTKALASCPCNKGVCMDVIDLLLKKEMESRAIICYIIMLEKGFRVHNEIRRDVLKFERGDELILSPN
Protein: Pum1 protein (Q7SXY5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSVACVLKRKAVLWQDSFSPHLRLPPPDRPLPSMPVVLSAAGHTPQPGPSPQAPAPTQGAGRSQDDAMVDYFFQRQHGDQPGYNNCKHRWPTGDNIHADNQVRSMDELNHDFQALALEGRAMGEQLLTGKKFWETDDSGKDGPKGIFLDQWRDSAWGASDHSVSRPIMVQRRPGQGFHGVGEAGSVLSPRSESGGLGVSMVEYVLSSSPAEKMDSCLRKGAYGPRDSEADDPEKRVEQKPKTTFDPERKELKETEPDVLDNPNGLPNQNGLDVDVKDFSRTPGNCPPTGQEVELGGPEMVGGAGPKPAEEFSNVETQNVTLDPMESVSMETLQFEYPGGQLPLDSTAATVGLFDYNSPQQLFQRPNALAVQQLTAAQQQQYALAAAQQPHIGLAPAAFVPNPYIISAAPPGTDPYAAGLAAAATLGPAVMPPQYYGVTPWGVYPANLFQQQAATPSNSANQQSAAQNQQNQQQVMRAGGNQRPLTPSQGQQGQQTEQLVAAAAVNSALAFGQGLAAGVPGYPVLAPAAYYDQICHSFVYL
Protein: Chorismate synthase (EC 4.2.3.5) (5-enolpyruvylshikimate-3-phosphate phospholyase) (O74413)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Chorismate mutase
- Pentafunctional AROM polypeptide
- Tryptophan synthase
- Multifunctional tryptophan biosynthesis protein
- Probable anthranilate synthase component 1
- Probable prephenate dehydrogenase [NADP
- Anthranilate phosphoribosyltransferase
- Putative aminodeoxychorismate synthase
- Putative prephenate dehydratase
- Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited
Sequence:
MSSFGTLFKVTTYGESHCKSVGCIVEGCPPGMNLTESDVQVQLTRRRPGQSNLTTPRNEKDKVQIQSGTEFGVTLGTPIGMLVLNQDQKPHDYSDMDNYPRPSHADYTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLLEAYGVEIVAFVSSVGKIAIPLHETASSAILDPEDDTFESPITAEYLKFLNKITREEVDKTTVRCPHAATAAKMAERITRARDNHDSIGGTVTCVIRNVPTGLGEPCFDKLEAKLAHAMMSIPATKSFEIGSGREGCKVAGSKHNDLFYRNADTGKLGTLTNNSGGVQGGISNGENVYFTIGFKSPATIGVEQSTSRYDGSDGVLAAKGRHDPCVVPRAIPIVEAMAALVVMDAVMIQQSRIASRNLLPNAQ
Protein: Similarity to HELICASE MOT1 (Q8SVZ5)
Organism: Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Interaction partners:
- TRANSCRIPTION INITIATION FACTOR TFIID
- CLASS 2 TRANSCRIPTIONAL REPRESSOR similar NCB1_yeast
- TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN
- Transcription initiation factor TFIID subunit 2
Sequence:
MNRLEKFFTTLNTAQSKVLKGYTTDELVSQIKEYVDFTPYILKQTYRLLCGQASEDRRNGARILRSLMFQFKLVTDFKIEYKESSSIYLSSTGEQFNVQAPSIQEQKRMVRKIAKLEHVEANFLSDIDFKAGSGEAIKRHKVDERPIENVLDFFEQISDNLLSYEWYKRHGAFLAFAAMFSEIDNGGDIQIRVDSKLFSKIYEILVTDKFNDFVDDRTVAPVRDAAAYLLSRIYPLIGPNDIIEQLVGFLDSGDWQVQFSGLIALGYLKEFVEDKDGLCRKLVSLLSSPDEDIKLLSAELLCHFPITDSLDLVLEKCWKNIESEELISVSKTSNLSLLTKIYRENPELSIPPERLKDIFPCFTSPVPEVRTSILNMVKNLSEESIDFLVAEVVLIEEKDEIREMAIKLLKKRRDLPKNLILHFMNVIGGSLYEPYSEDDFVSYEDLYFTKSGINVVGKDEILKNRCLLFECIMKSGLPDLQSTIETTTSRTFISLYRSVQALVKDTPYTPANIEELEYYFDRCKDLKMAPLKEFKKKLSAPGIRSIHPMVDPLYSDYTRMVASIEFPGLERATALFEVETCKQFLHLFSKMITEYYDAEKISIDNFLLKAYEGLASGKDGFLSFFEVFNTRLLAHSFFHKIGSLENRLDFFSKTIHIYTKTSQIQKIGFVFDDALREKNITVINGFMRSLEFNEKFVRKALEDLDVELLDAVLMSGDHSFNPLFVKPLLRNISGNIDREASSKVLSKVIPTLGFSTNTKISKDLLEMIEREKKSLESLLDAGKIPEYHIKCPISVKLRDYQMEGVKWLNFLYSFSLNGILADDMGLGKTLQVLTFLCSEIYKTNRKVLVICPSSLTGHWKSEVKKFFPFVAAEIYKREDRDTYSILISSYETFRNDYLNFIEKDWFYVVVDEGHVLRNKQTILYSRMNMIRCSRKMVLTGTPVHNSVEDLISLFNFLMPNYIGPEKEYGSLNVKMSDSEIEKTHKRLDLLHRKVLPFILRRLKIDVLKDLPPKIIRDITVELGPVQEKLYREIDEKGGKESLGDAELEYGKVDQKNVGFKRTRDLFLAVSHIGHFKDSTEVSCKVKALEDIISLCGGEDLGSKILIFFQFKSTIDLVIKDIMKKYKFKYSRLDGSVPSAARTKIAEEFNTGTTQMLFLTTQVGGLGLNLTGADTVVMYEHDWNPFNDLQAMDRAHRIGQKRTVNVFRFIARNTLEEKVMNLQSFKMFVANSLVSQQNADIETMDTKDLLERFQVPG
Protein: tRNase Z TRZ2, chloroplastic (EC 3.1.26.11) (Chloroplast ribonuclease Z) (Chloroplast RNase Z) (Short tRNase Z 2) (Zinc phosphodiesterase CPZ) (tRNA 3 endonuclease) (tRNase ZS2) (AthTRZS2) (Q8L633)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Zinc phosphodiesterase, which displays tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:19411372}.
Interaction partners:
- tRNAse Z TRZ4, mitochondrial
- tRNase Z TRZ3, mitochondrial
- tRNase Z TRZ1
- Dynamin
- Ribonuclease J
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- Ribonuclease E/G-like protein, chloroplastic
Sequence:
MQLSSSFPISPPKIFPSTKHHKPPVITHQLAAQIQSNRRHFVSPVKVSGYFSSISRAIEEEEEYRKARAAVNRKGVELESYAIEGISVGGHETCVIVPELKCVFDIGRCPSRAIQQKFLFITHAHLDHIGGLPMYVASRGLYNLEPPKIFVPPSIKEDVEKLLEIHRTMGQVELNVELIPLAVGETYELRNDIVVRPFATHHVIPSQGYVIYSVRKKLQKQYAHLKGKQIEKIKKSGVEITDTILSPEIAFTGDTTSEYMLDPRNADALRAKVLITEATFLDESFSTEHAQALGHTHISQIIENAKWIRSKTVLLTHFSSRYHVEEIREAVLKLQSKVSAKVIPLTEGFRSRYS
Protein: TIR domain-containing protein (A0A060WMR1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Interleukin 1 receptor accessory protein
- Interleukin-1
- Interleukin-1
- Death domain-containing protein
- Interleukin-1
- Interleukin-1
- Interleukin-18
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MRYWRTSLSLPVIHHLNYAILSDAEMVNQSRVLLDTLLDSAAIDTTKKLRCEAFCGQNIEDNCHVWWEINGVKVRLQQQGYTVNTTSEVEVSSMRRIFTAILTINTVTMRDLQSKFTCVAMNDQKWYYAVVTLKLRGFMFMGLCVVLLLFFLLAAVAVKVFDIDLALLFRGVFKCCGRSEDGKVYDAYVVYQMDGLDQEREEKVYHFVSIVLPTVLEKKCGFRLFIHGRDDLPGEDRMELVEACMQLSRRLIVILTPSSSTLLGSGGQGSCGQWGYTSLLTTAEDYECQVGLYQALVHSEMNVILIQLGDMGEGGYTHLSPGLQHLVRKSAPLMWHEGRRGSMLPNSSFWKRVRYMMPWPRSTSFDNQLI
Protein: ATP-dependent RNA helicase (EC 3.6.4.13) (Q38AQ5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Pescadillo homolog
Sequence:
MPAELPPSAPQFFKDLAELCPSETLRRQLLELQRTRNWNDMTAVQRAAIPLALEHRDILCIAPTATGKTFGYLFPSMLRLAMYAGTDGSSNLTGSVSEDLNRPNIEKLMQDKMEKGEVCRYCELSVTEVRVCPLTGQPHPDPVPEDAAKQQRSPMWVSELSSVAEPLLLVLVPTSQLVMQVYHLCKKLDADFRVKFLVRASSAEEQKRHLNALEGCDVLITTPETMLPALYKRKLSLKRVKVLVLDEVDDLLSTNHFEKVKIILGALPKGPQRPQRLLFGASLPPSVYQMIKEQMLLPSHRFVLVDVKTDKLGHPIAPAPGSICGAAVCASITHVVFMVSQAEKISRLAWLYSSGKLRKDQRTLIFCNSRHNVAYVCERLQNLVPGLRVTTLTSHSSATGKTGTMKLFSRGASTCLICTDILSRGIDFADVIYVVHYDVPTEFETWVHRSGRCGRRGLRGYCYTFFQPENVRLAKPLVAHLRQTQQLIPPKLQEYARQSLIDVFKTSLFYHPTRRYRPRDPQQQAPVLGRATPRFPDYKQDRLNKNFRPL
Protein: Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) (Phosphoglucomutase-2) (Q9D0F9)
Organism: Mus musculus (Mouse)
Function: This enzyme participates in both the breakdown and synthesis of glucose.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- UTP--glucose-1-phosphate uridylyltransferase
- Glycogen phosphorylase, brain form
- Glycogen phosphorylase, liver form
- Glycogen phosphorylase, muscle form
- Glucose-6-phosphate isomerase
- Glycogen debranching enzyme
- Phosphopentomutase
- GDH/6PGL endoplasmic bifunctional protein
- Hexokinase-1
- Glucose 1,6-bisphosphate synthase
Sequence:
MVKIVTVKTQAYPDQKPGTSGLRKRVKVFQSNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGTGSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT
Protein: Mediator of replication checkpoint protein 1 (DNA replication checkpoint mediator mrc1) (Q9P7T4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the replisome and is required for rad3-dependent activation of the checkpoint kinase cds1 in response to replication fork arrest. Phosphorylation allows it to mediate the activation of cds1.
Subcellular location: Nucleus {ECO:0000269|PubMed:14585996}. Note=Associated with chromatin.
Interaction partners:
- Serine/threonine-protein kinase cds1
- Mating-type switching protein swi1
- Swi1-interacting protein swi3
- Protein kinase rad3
- Cell division control protein 45 homolog
- DNA replication licensing factor mcm2
- DNA replication licensing factor mcm4
- DNA repair protein crb2
- Cell cycle serine/threonine-protein kinase hsk1
- Minichromosome loss protein 1
Sequence:
MASLDENADELHRMDSSDEASINDDQEDILDTPRTRVRKMLASVDMQLSSNAVSEASLDKESTVGNLENQKNRSYSSEIYLHSDTNFLSNFDSAYERVRRLLNQQGGKSSLQKKEVEQIETQEGGDNAKGSPSSENKDSDRNSRLQQLIEKKRNALKKEQEDLIQNSATSHSKSDNLDSESADDSDLADESELSKKYTSDRKIRNASKKALLELHRNTARLTRETALKPEVVVKKKVTLREFFQKIGFKNDNQLENKAISEEEANSTEPPNVEKEEPKPSVDRSTGIVNSEDIKELSVEDDSLELKEITPEALDIGQTSLFTTLNQTQVKKEDNKKFLLKEINAKLNEDDIDSELEIEVKPKTTALDNIEKSKLSEENEHGIKGKLKQLAEIKLSKDGKPFENEFNIKSFNRNLVKRAAVMAKLQRNQLEEELKAKGIYKPTIQGEKEEEEDPLERARNDAEKIRQLEKASGNASDEGELNDEEEVISSSNTPSTKAKTTNKVIISDVIIEATQAEPKRRQKNSRVVFDEEDLTGDSHGSSNMKISESDDESNGDMIRDSFDRLSSESIKDSQKTEELHDSFGINDEVDQSTSLYVQNSQPSASQLTIVDATYSQPPPRWESSSRDDKTNTSSTQPSQVDSLVPTQLDSTIPTQIDSVQRNKDQDDEEILEERRESRRDSKTFLSRTMLYNKDTGKADSAWASDLIEEQAIESDDEYAGIGGLSDDGLSDSDAELEVQNMIDDETTIQKGEVASMAQFAKDQEMDRDEKLVKQLMKDVTTGALRKRNRNGFAALDDSDDEDYSNLRREKLKELRRQKLLEDGNLNVLEGDKRKAFLATVEDSLVSSKDNLTWLDATVEDSGVGSSDLGDEYLYSEQSLNHEEEEQMEEELSEIFSSGGPNVVDRVYLKKSSTRHTSDNNSLEEVLPIFPGVRKLVSNSQSEKIGDLSNDNSMGAKSYKTPIISSTQRPQGRKFRGLMNQSSKADISRTVDAGSIKVVPNSQSANPPRLLASLNNYSDFD
Protein: Tubulin polymerization-promoting protein family member 2 (Q0P5Y3)
Organism: Mus musculus (Mouse)
Function: Probable regulator of microtubule dynamics required for sperm motility (Probable). In contrast to other members of the family, has no microtubule bundling activity (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P59282}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:30680919}. Note=Present in the middle piece of sperm tail. {ECO:0000269|PubMed:30680919}.
Interaction partners:
Sequence:
MASEAERTFHRFAVFGESSSSSKEITNKNFSKLCKDCDIMDGKAVTSTDVDIVFSKVKAKNARTINFQQFQEAMKELGQKRFKGKNPDEALQGVFKLMEGKDPATTGVTKSTTVGGVDRLTDTSKYTGTHKERFDESGKGKGIEGREETTDNSGYVSGYKGAGTYDKKNQ
Protein: Ceramide kinase-like isoform 14 (Ceramide kinase-like isoform 30) (G0XYH3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDCIPTLVGAELPLGFIPAGSTNALAHSLFGTPHVVTATMHIILGHIRSVDVCTFSSAGKLLCFGFSAMFGFGGRTLALAEKYRWMSPSQRRDFAIIKALAKLKPEDCKISFLLAGCSQNKQERKSQRSAESDCGGHWQTIQGQFLNISIMAMPCPCSMAPRGFTPDTRLHNGSMALRVVRNTTRSEFVKHLKRHSSVKNQGLYRYN
Protein: Endothelial PAS domain protein 1b (Endothelial PAS domain-containing protein 1b) (Epas1 protein) (B3DJD1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- hypoxia-inducible factor-proline dioxygenase
- Aryl hydrocarbon receptor nuclear translocator.
- Egl-9 family hypoxia-inducible factor 3.
Sequence:
MTAEKEKKRCSSERRKEKSRDAARCRRSKETEVFYELAHHLPLPHSISSHLDKASIMRLAISFLRTRKLVNSGYNTPTEMTDADRLMDSWYLKSLGGFITVVTSDGDMIFLSENINKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKAGIGKKGKELSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKVCNGCPARVLCGFKEPPLTCVVMMCEPIVHPSNIDTPLDSKTFLSRHSMDMKYTYCDERVTELMGYNPEDLLGRSAYEFYHALDAENVTKSHQNLCTKGQAVSGQYRMLAKNGGYVWVETRGTVIYNSRNSQPQCIVCVNYVLSDVEEKSLIFSMDQTESLFKPHKLNGFFSPKEALGSDPADLLFTKLKEEPEDLTQLAPTPGDTIISLDFGQSQYEEHTVYNKVSSVAQTVSHPVHDGHRTSYSGEMAKMAATFSVPQSAPPSSATPSLSSCSTPSSPDDYYTPVDSDLKVELTEKLFSLDTQEAKTSRNQETDLSDLDLETLAPYIPMDGEDFQLNPICPEEPPSEIGTLGTNQQCFSNITSLFQPLSSPSAAHYQPKMSSGGDKQNINGGSVESWPPVPYSRDPMQMPPYHDPASTPLSSMGGRQNLQWPPDPPLPSKAGMMDPLAAKRSCQGMPANRMAPFMQRPMENFVQNYRDTSPARLALANSFKRSFSQMAMAETPPTKSQQTVWKKLRHESCAVMERKSLSSSALSDKSMAHNGGMDHQHRKSQYSGNQNGQPTKHYREQFCNYREFNMQPSSKMDGIASRLIGPSFETYSLPELTRYDCEVNVPLQGNLHLLQGSDLLRALDQAT
Protein: Probable ubiquitin-conjugating enzyme E2 31 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 31) (Ubiquitin carrier protein 31) (Q9C8X7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
Interaction partners:
- E3 ubiquitin-protein ligase UPL4
- E3 ubiquitin-protein ligase UPL3
- At2g15580
- Translation initiation factor eIF2 assembly protein
- Egg cell-secreted protein 1.1
- OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 1
- Ubiquitin-activating enzyme E1 2
- Ubiquitin-ribosomal protein eL40y fusion protein
- Ubiquitin-ribosomal protein eL40z fusion protein
- Ubiquitin-activating enzyme E1 1
Sequence:
MFKKMDKKAAQRIAMEYRAMISKESLFSIGQNSNNIYEWTAVIRGPDGTPYEGGMFNLSIKFPTDYPFKPPKFTFKTPIYHPNINDEGSICMNILKDKWTPALMVEKVLLSILLLLEKPNPDDPLVPEIGQLFKNNRFQFDQRAREFTARHANN
Protein: DNA-directed RNA polymerase IV subunit 7 (Q8LE42)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase IV which mediates 24-nt short-interfering RNAs (siRNA) accumulation. Implicated in siRNA-directed heterochromatin formation through the action of DCL3 and AGO4, and subsequent DNA methylation-dependent silencing of targeted sequences. Essential component of a self-reinforcing loop coupling de novo DNA methylation to siRNA production. Required for intercellular but not intracellular RNA interference (RNAi) leading to systemic post-transcriptional gene silencing. Involved in the maintenance of post-transcriptional RNA silencing.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA-directed RNA polymerases II, IV and V subunit 8B
- DNA-directed RNA polymerases II, IV and V subunit 9B
- DNA-directed RNA polymerases II, IV and V subunit 11
- DNA-directed RNA polymerases II, IV and V subunit 3
- DNA-directed RNA polymerases IV and V subunit 3B
- DNA-directed RNA polymerases IV and V subunit 4
- DNA-directed RNA polymerases II, IV and V subunit 10
- DNA-directed RNA polymerases II, IV and V subunit 6A
- DNA-directed RNA polymerases II and IV subunit 5A
- DNA-directed RNA polymerases IV and V subunit 5B
Sequence:
MFIKVKLPWDVTIPAEDMDTGLMLQRAIVIRLLEAFSKEKATKDLGYLITPTILENIGEGKIKEQTGEIQFPVVFNGICFKMFKGEIVHGVVHKVHKTGVFLKSGPYEIIYLSHMKMPGYEFIPGENPFFMNQYMSRIQIGARVRFVVLDTEWREAEKDFMALASIDGDNLGPF
Protein: Ribulose-phosphate 3-epimerase-like protein 1 (EC 5.1.3.1) (Ribulose-5-phosphate-3-epimerase-like protein 1) (Q2QD12)
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
Interaction partners:
- Ribose-5-phosphate isomerase
- Transketolase-like protein 1
- Transketolase
- Transketolase-like protein 2
- 6-phosphogluconate dehydrogenase, decarboxylating
- Xylulose kinase
- Transaldolase
- Ribulose-phosphate 3-epimerase
- RNA-binding protein 45
- GDH/6PGL endoplasmic bifunctional protein
Sequence:
MASGCKIGPSILNSDLANLGAKCLQMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGEQKFMEDMMPKVHWLRTQFPSLDIEGDGGVGSDTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNICSEAAQKRSLDR