wanglab/gogpt-training-data huggingface dataset:
Protein: Histone-lysine N-methyltransferase TRX1 (OsTrx1) (EC 2.1.1.364) (Protein SET DOMAIN GROUP 723) (SET family protein 33) (OsSET33) (Q6K431)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Possesses histone H3 methyltransferase activity in vitro. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Functions as a receptor for the lipid messenger phosphatidylinositol 5-phosphate (PI5P), which regulates negatively its transcriptional activation activity (By similarity). Involved in the regulation of flowering time and floral induction under long day (LD) conditions. Acts as an activator of flowering under LD conditions. May function through binding to EHD3, a repressor of GHD7.
Subcellular location: Nucleus {ECO:0000269|PubMed:24420930}.
Interaction partners:
- Os03g0207900 protein
- Probable lysine-specific demethylase SE14
- Os11g0146500 protein
- Os12g0143200 protein
- Os11g0145700 protein
- Histone H4
- Histone H4
- Polycomb group protein EMF2B
- Os06g0258900 protein
- Expressed protein
Sequence:
MVIAVEGGFVHEEEEVDHPIRYLPLGRVYSSSAPCPLPKKPRSAEDGKPPVIVYYRRRRKKPRVEGPPPSPATAPPMLHPREDDEDEEVTRRKGSLKYELLSLGQAPPALGGDGEEPARRRCLRRSGGAERRGYFSEPKRRQRQGVHKEAASSAGRRWLELEIEAADPLAFVGLGCKVFWPLDEDWYKGSITGYNEATKKHSVKYDDGESEDLNLADERIKFSISSEEMKCRNLKFGISNLNKRGYDELLALAVSLHDYQGLDPGDLVWAKLTGHAMWPAVVVDESNVPANRALKPGRLDQSILVQFFGTHDFARIKLKQAVPFLNGLLSSLHLKCKQARFYRSLEEAKEFLCTQLLPENMLQLQKSMEKGSSDANSNKDVHSCDNLSEDKTAESGGDYDEMTPIELGNLRVSKLGRIVTDSDYFHNKKHIWPEGYTAFRKFRSVKDPHVVILYKMEVLRNSDIKARPLFRVTSEDGTQIDGSTPNTCWKEIYCRLKEKQRNVASGLDRDVCQGSGSYMFGFSNPQIRQLIQELPNARSCLKYFENAGDTFRGYRAVHVNWKDLDYCSVCDMDEEYEDNLFLQCDKCRMMVHARCYGELEPLNGVLWLCNLCRPEAPRVSPRCCLCPVTGGAMKPTTDGRWAHLACAIWIPETCLKDVKRMEPIDGLSRINKDRWKLLCSICGVAYGACIQCSHPTCRVAYHPLCARAADLCVELEDDDKIHLMLLDEDEDPCIRLLSYCKKHRQPSTERPSLESNLAKPAVVVQTDAVPPSGCARTEPYNIHGRRGQKQPQVMATASVKRLYVENMPYIVSGFCQNRVGHDAISEPIQSVGFLDVAHQEAVGNVSSMIEKYKSMKATFRRRLAFGKSRIHGFGVFAKVSHKAGDMMIEYIGELVRPPISDIRERRIYNSLVGAGTYMFRIDDERVIDATRAGSIAHLINHSCEPNCYSRVISVLGDEHIIIFAKRDINPWEELTYDYRFVSSDQRLPCYCGFPKCRGVVNDVEAEGQSAKIRVNRSELFQQ
Protein: Transcription factor BHLH156 (Basic helix-loop-helix protein 156) (OsbHLH156) (bHLH transcription factor bHLH156) (A0A0N7KIY3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor involved in positive regulation of genes involved in strategy II iron acquisition, including genes for mugineic acid (MA) family phytosiderophores biosynthesis, and genes involved in S-adenosylmethionine cycle and iron transport. May play a role in the regulation of iron deficiency response by promoting the nuclear localization of IRO2. Possesses transactivation activity in yeast.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:31574173}.
Interaction partners:
- Protein IRON-RELATED TRANSCRIPTION FACTOR 2
- Os08g0406400 protein
Sequence:
MEHHHLLLQLSPPPPPPPLPAAHLMMSPSFFDAGVFADVGGDWMEDLMHLGELFGVGVGGDDDDNGGVDGGVGGGDDRMQEWQNNCEGAGSPDHQPSCGDGDGDGDGDVSPRDGELGDGDGDNSATRKRRDRSKTIVSERKRRVRMKEKLYELRALVPNITKMDKASIIADAVVYVKDLQAHARKLKEEVAALEEARPIRPPPPSAAAQRPQRQPRRVAAAAAQLARAADAAAVTTAAAAPHGARVAHVGAAQVGEGRFFVTVECEPAAAAARGGGGGVAAPVCAAVESLSCFTVESSTVGCSPDRVVATLTLKVSEAEEDVSAISECTVKLWVMAALLKEGFRPQPTVQIS
Protein: Pulmonary surfactant-associated protein B (SP-B) (Pulmonary surfactant-associated proteolipid SPL(Phe)) (P22355)
Organism: Rattus norvegicus (Rat)
Function: Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
Subcellular location: Secreted, extracellular space, surface film.
Interaction partners:
- Surfactant protein C
- Pulmonary surfactant-associated protein A
- Uteroglobin
- Pulmonary surfactant-associated protein D
- Napsin A aspartic peptidase, isoform CRA_a
- Pro-cathepsin H
- Homeobox protein Nkx-2.1
- Advanced glycosylation end product-specific receptor
- Adhesion G protein-coupled receptor F5
- Phospholipid-transporting ATPase ABCA3
Sequence:
MAKLHLQWLLLLPTLCSLGAATESASSPDCAQGPKFWCQSLEQAIQCRALGHCLQEVWGHAGANDLCQECEDIVHLLTKMTKEDAFQDTIRKFLEQECDILPLKLLVPRCRQVLDVYLPLVIDYFQGQIKPKAICSHVGLCPLGQTKPEQKPEMLDAIPNPLLNKLVLPALPGAFLARPGPHTQDLSEQQLPIPLPFCWLCRTLIKRVQAVIPKGVLAVAVSQVCHVVPLVVGGICQCLAERYTVLLLDALLGRVVPQLVCGLVLRCSTADAIGPALPALEPLIEKWPLQDTECHFCKSVINQAWNTSEQAMPQAMHQACLRFWLDRQKCEQFVEQHMPQLLALVPRSQDAHTSCQALGVCEAPASPLQCFQTPHL
Protein: Single-stranded DNA-binding protein, mitochondrial (Mt-SSB) (MtSSB) (PWP1-interacting protein 17) (Q04837)
Organism: Homo sapiens (Human)
Function: Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA). In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays a crucial role during mtDNA replication by stimulating the activity of the replisome components POLG and TWNK at the replication fork. Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity. In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK. May also function in mtDNA repair.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:18063578, ECO:0000269|PubMed:31550237, ECO:0000269|PubMed:31550240}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:18063578, ECO:0000269|PubMed:31550240}.
Interaction partners:
- Twinkle mtDNA helicase
- Small ribosomal subunit protein bS6m
- Transcription factor A, mitochondrial
- DNA polymerase subunit gamma-1
- Ribonuclease H1
- Integrator complex subunit 3
- Large ribosomal subunit protein bL21m
- SOSS complex subunit C
- DNA-directed RNA polymerase, mitochondrial
- Small ribosomal subunit protein mS33
Sequence:
MFRRPVLQVLRQFVRHESETTTSLVLERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSEVYQLGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSRIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFLSDQTKEKE
Protein: Thromboxane A2 receptor (Prostanoid TP receptor) (D0EXE2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Guanine nucleotide-binding protein subunit alpha
- Guanine nucleotide-binding protein
- Guanine nucleotide-binding protein subunit alpha
Sequence:
MLSIQQYNSTVLAEDEALVNQSHHYVAPLRCRENLTTTSPTAAGLSMTLGIVSNIIALAILANAYSRRSKTTKATFLLFASSLVVTDLVGHVIPGALVLHLYLSGTGPCLPAVPDGTCQFLGGSMVFFGLCPLFLGCAMAVERCIGVTRPLLHKRLVCTTQTKIVMVMVWLLALSVAFLPFFRLGSYTYQYPWTWCFINVLDETNVTDVIFVVLFSGLGLASLAVALVCNTISGVTLVAARLRKKQKQESIRQSKKDKQESVRLSRKDKQNKSSKTHDIEMVVQLVGIMVTSCICWSPLLIFGLMSVIRSSISSMGDDLEMSYRTLLVMGVRLASWNQILDPWVYILLRRAILRKIYYLTTGRTGRKGSTFRRWEASSFQNSVKKAINQT
Protein: La protein (Q9N9G6)
Organism: Trypanosoma brucei
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPLSSENKQKLQKQVEFYFSDVNVQRDIFLKGKMAENAEGFVSLETLLTFKRVNSVTTDVKEVVEAIRPSEKLVLSEDGLMVRRRDPLPESIQTDHQTVYVKPVPPTATLEQLTEFFSKHGTVQAVWRRYFAGKKDAPPESRTKPSVFVVFNSSEEAEAFQKAPPMYDDVQLTAEMKTTYLERKAEEIAAKKSSKTKNGGATDRAEKKTPPMPLGSSYRVSGCGEMESFATVKNLWPVEEQKGIRYVFMPDKESALLIFQDTQTGEKMVADLKSRGTTLNGKQPDIKKLEGDDEQKLLENVEKEIVDRAMQSANNRSGRGGRGGRGGRGHKRSRE
Protein: Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) (Q9QUK5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Nucleus, Cajal body {ECO:0000250}. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. {ECO:0000250}.
Interaction partners:
- Heat shock protein beta-2
- Heat shock protein beta-3
- Filamin-C
- Heat shock protein family B
- Bcl2-associated athanogene 3.
- Filamin, alpha
Sequence:
SSSSSSASRALPAQDPPMEKALSMFSEDFGSFMLPHSEPLTFPARPGGQGNIKTLGDAYEFTVDMRDFSPEDIIVTTSNNHIEVRAEKKP
Protein: Adenine phosphoribosyltransferase 2 (APRT 2) (EC 2.4.2.7) (P36973)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. May lack catalytic activity.
Subcellular location: Cytoplasm.
Interaction partners:
- Adenylosuccinate lyase
- Adenine phosphoribosyltransferase 1
- Adenosine kinase
- Inosine triphosphate pyrophosphatase
- Hypoxanthine-guanine phosphoribosyltransferase
- GMP synthase
- Adenine deaminase
- Guanylate kinase
- Bifunctional purine biosynthesis protein ADE16
- Purine nucleoside phosphorylase
Sequence:
MSISESYAKEIKTAFRQFTDFPIEGEQFEDFLPIIGNPTLFQKLVHTFKTHLEEKFGKEKIDFIAGIEARGLLFGPSLALALGVGFVPIRRVGKLPGECASITFTKLDHEEIFEMQVEAIPFDSNVVVVDDVLATGGTAYAAGDLIRQVGAHILEYDFVLVLDSLHGEEKLSAPIFSILHS
Protein: TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein) (O95759)
Organism: Homo sapiens (Human)
Function: May act as a GTPase-activating protein for Rab family protein(s).
Interaction partners:
Sequence:
MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVAPFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQALMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEKFGDQSVEQIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMMSCYWEQPRPMASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDDNMDQLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLRNPLLSTSRPLVFGKPNGDAVDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSCSQECGEELRASAPSPEDSVFADTGKTPQDSQAFPEAAERDWTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAKINQYNLKTFEMSHQSQSELKLSNL
Protein: RE55465p (Suppressor of variegation 2-10, isoform F) (Q5BIG7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPFPSLQECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTNLELLAPKVQEVYAQSVQEQNATLQYIDPTRMYSHIQLPPTVQPNPVGLVGSGQGVQVPGGQMNVVGGAPFLHTHSINSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQKVEVISDDIELISDDAKPVKRDLSPAQDEQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVASSTSNGSGGGQRAYTPAQQPQQSGTLDPFLQ
Protein: DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19) (P62487)
Organism: Homo sapiens (Human)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:9852112}.
Interaction partners:
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- Transcription elongation factor SPT5
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB11-a
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
Sequence:
MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS
Protein: Perilipin-2 (Adipophilin) (Adipose differentiation-related protein) (ADRP) (P43883)
Organism: Mus musculus (Mouse)
Function: Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
Subcellular location: Membrane {ECO:0000305|PubMed:1518805}; Peripheral membrane protein {ECO:0000305|PubMed:1518805}. Lipid droplet {ECO:0000269|PubMed:12562852, ECO:0000269|PubMed:9392423}.
Interaction partners:
- Heat shock cognate 71 kDa protein
- 1-acylglycerol-3-phosphate O-acyltransferase ABHD5
- Butyrophilin-like protein 9
- Erythroid membrane-associated protein
- Butyrophilin-like 6
- Butyrophilin subfamily 2 member A2
- Butyrophilin subfamily 1 member A1
- Butyrophilin, subfamily 3, member A3
- Butyrophilin-like protein 1
- Hormone-sensitive lipase
Sequence:
MAAAVVDPQQSVVMRVANLPLVSSTYDLVSSAYVSTKDQYPYLRSVCEMAEKGVKTVTSAAMTSALPIIQKLEPQIAVANTYACKGLDRMEERLPILNQPTSEIVASARGAVTGAKDVVTTTMAGAKDSVASTVSGVVDKTKGAVTGSVERTKSVVNGSINTVLGMVQFMNSGVDNAITKSELLVDQYFPLTQEELEMEAKKVEGFDMVQKPSNYERLESLSTKLCSRAYHQALSRVKEAKQKSQETISQLHSTVHLIEFARKNMHSANQKIQGAQDKLYVSWVEWKRSIGYDDTDESHCVEHIESRTLAIARNLTQQLQTTCQTVLVNAQGLPQNIQDQAKHLGVMAGDIYSVFRNAASFKEVSDGVLTSSKGQLQKMKESLDEVMDYFVNNTPLNWLVGPFYPQSTEVNKASLKVQQSEVKAQ
Protein: Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2) (O43526)
Organism: Homo sapiens (Human)
Function: Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability. KCNQ2/KCNQ3 current is blocked by linopirdine and XE991, and activated by the anticonvulsant retigabine. As the native M-channel, the potassium channel composed of KCNQ2 and KCNQ3 is also suppressed by activation of the muscarinic acetylcholine receptor CHRM1. KCNQ2-KCNQ3 channel is selectively permeable to other cations besides potassium, in decreasing order of affinity K(+) > Rb(+) > Cs(+) > Na(+). Associates with Na(+)-coupled myo-inositol symporter SLC5A3 forming a coregulatory complex that alters ion selectivity, increasing Na(+) and Cs(+) permeation relative to K(+) permeation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10788442, ECO:0000269|PubMed:9836639}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Potassium voltage-gated channel subfamily KQT member 3
- Potassium voltage-gated channel subfamily KQT member 5
- Calmodulin-1
- Potassium voltage-gated channel subfamily KQT member 1
- Calmodulin-like protein 5
- Calmodulin-like protein 3
- Ankyrin-3
- Calmodulin-like protein 4
- Calmodulin-like protein 6
- Inward rectifier potassium channel 4
Sequence:
MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAGGAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSPCRGPLCGCCPGRSSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK
Protein: Transcription factor MYBS3 (Myb-related protein S3) (OsMYBS3) (Q7XC57)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription repressor that binds to 5'-TATCCA-3' elements in gene promoters. Contributes to the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements. Transcription repressor involved in a cold stress response pathway that confers cold tolerance. Suppresses the DREB1-dependent signaling pathway under prolonged cold stress. DREB1 responds quickly and transiently while MYBS3 responds slowly to cold stress. They may act sequentially and complementarily for adaptation to short- and long-term cold stress.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:20130099}.
Interaction partners:
Sequence:
MTRRCSHCSHNGHNSRTCPNRGVKIFGVRLTDGSIRKSASMGNLSLLSSAAGSTSGGASPADGPDAAPTAADGYASDDFVQGSSSATRDRKKGVPWTEEEHRRFLLGLQKLGKGDWRGISRNFVVSRTPTQVASHAQKYFIRQSNMTRRKRRSSLFDMVPDESMDLPPLPGGQEPETQVLNQPALPPPREEEEVDSMESDTSAVAESSSASAIMPDNLQSTYPVIVPAYFSPFLQFSVPFWQNQKDEDGPVQETHEIVKPVPVHSKSPINVDELVGMSKLSIGESNQETVSTSLSLNLVGGQNRQSAFHANPPTRAQA
Protein: Ataxin 2 (F8WB05)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
PSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQYKPTTNSSCKAALEEPKGQIPSSLLLLLPTGSTEN
Protein: DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha) (P9WGZ1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Interaction partners:
- Small ribosomal subunit protein uS13
- RNA polymerase sigma factor SigA
- Small ribosomal subunit protein uS8
- Small ribosomal subunit protein uS4
- DNA-directed RNA polymerase subunit beta'
- Small ribosomal subunit protein uS3
- DNA-directed RNA polymerase subunit omega
- DNA-directed RNA polymerase subunit beta
- RNA polymerase-binding protein RbpA
- Small ribosomal subunit protein uS11
Sequence:
MLISQRPTLSEDVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTEIILNLKSLVVSSEEDEPVTMYLRKQGPGEVTAGDIVPPAGVTVHNPGMHIATLNDKGKLEVELVVERGRGYVPAVQNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKNSISPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALPIDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIKLHQLGLSLKDSPPSFDPSEVAGYDVATGTWSTEGAYDEQDYAETEQL
Protein: Spindle assembly abnormal protein 6 (O62479)
Organism: Caenorhabditis elegans
Function: Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication.
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles, zyg-1 and sas-5 are required for centriole localization.
Interaction partners:
- Spindle assembly abnormal protein 5
- Spindle assembly abnormal protein 4
- Probable serine/threonine-protein kinase zyg-1
- Spindle-defective protein 2
- Spindle assembly abnormal protein 7
- Spindle-defective protein 5
- Suppressor of zyg-1 protein 20
- Centriolar and ciliogenesis-associated protein hyls-1
Sequence:
MTSKIALFDQTLIASLLQPLSLNQPDFKAYKTKVKLKISEQRNETSGEKELKFEISRSDDFEFLFSETLNNEKYQILARDHDLTVDFDAFPKVIIQHLLCKNIVKNLEEDGEVDARKKAGYHSIADPGKPTEINIILDAEKNFCSFELFSKTPISKGKIFSIKLHAVRGDHLISHLLKICSSQAVKLSTFYKSADELASLRQKCGDLEKQVEKLSGVKEEFEEMSEKFKELEDEVELVKEERENIRLLVEDKEDEVADLKQDTESLQKQLEENQEELEIVGNMLREEQGKVDQLQKRNVAHQKEIGKLRAELGTAQRNLEKADQLLKRNSQQQNQQSLDMRKLGELEADLKEKDSMVESLTETIGILRKELENEKLKAAENMDSFEKLSMENENLKEKIAHYRAQRFSPAPSGLPGLQTGLTNRLTPSFKPVLGPHTPYGANLNSRTPFRDNTTLNFQNSTIATPHAFRFNSQLIADETTGSSVTNTPPAQR
Protein: Putative peroxisomal acyl-coenzyme A oxidase 1.2 (EC 1.3.3.6) (Q9ZQP2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs.
Subcellular location: Peroxisome {ECO:0000305}.
Interaction partners:
- Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2
- 3-ketoacyl-CoA thiolase 1, peroxisomal
- 3-ketoacyl-CoA thiolase 5, peroxisomal
- Peroxisomal fatty acid beta-oxidation multifunctional protein AIM1
- 3-ketoacyl-CoA thiolase 2, peroxisomal
- Probable enoyl-CoA hydratase 1, peroxisomal
- Probable acyl-CoA dehydrogenase IBR3
- Acetyl-CoA acetyltransferase 2
- Acetyl-CoA acetyltransferase 1
- Acyl-coenzyme A oxidase 3, peroxisomal
Sequence:
MERVDHLADERNKAEFNVDDMKIVWAGSRHAFDVSNRMSRLVANDPVFEKSKRAVMSRKELFKNTLRKSVHAWKLINELRLSDEEGLKLRSFMDQPGFLDLHWGMFVPAIKGQGTEQQQQKWLSLATKMQIIGCYAQTELGHGSNVQGLETTATFDPKTDQFIIHSPTQTSSKWWPGGLGKVSTHAVIYARLITNGKDHGVHGFIVQLRSLDDHSPLPGITVGDIGMKFGNGAYNSMDNGFLMFDHFRIPRDQMLMRLSKVTREGKYVASDVPRQLVYGTMVYVRQSIVSNASTALARAVCIATRYSAVRRQFGSHDGGIETQVINYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTKRLEASDFATLPEAHACTAGLKSMTTSATSDGIEECRKLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMKTVSQLGSGKAPSGTTAYMGRAKHLLQCSSGVRNARDWLNPGMVLEAFEARALRMAVTCANNLSKFENQEQGFSELLADLVEAATAHCQLIVVSKFIAKVEGDIEGKGVKKQLKNLCYIYALYLLHKHLGDFLSTNSVTPEQASLANQQLRSLYSQVRPNAVALVDAFDYTDQYLGSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYREYIRPLIKQRFRSAKL
Protein: Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC) (P40518)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular location: Cytoplasm, cytoskeleton, actin patch {ECO:0000269|PubMed:11248049}.
Interaction partners:
- Actin-related protein 3
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2/3 complex subunit 1
- Actin-related protein 2
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 2
- Proline-rich protein LAS17
- Protein LDB17
- Actin
- Fimbrin
Sequence:
MEADWRRIDIDAFDPESGRLTAADLVPPYETTVTLQELQPRMNQLRSLATSGDSLGAVQLLTTDPPYSADAPTKEQYFKSVLEALTQVRQADIGNVIKNLSDSQRDVLVKYLYKGMSVPQGQKQGGVLLAWLERITQVSGVTPIVHYISDRRTV
Protein: Pleckstrin homology domain containing, family A member 5 (A0A0N4SWD7)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAADLNLEWICSLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPTGWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNDQTVATMTSEDKKERPISMINEASNYNMASDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIAMLTAEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITTDSASTKETNNIPNHRVLIRPEVQNHQKNKEISKIEEKRALEAERYGFQKDGQDRPLTKINSVKLNSLLSEYESGPDCPPQNVHYRPINVNSSDGKAVNVSLADVRGGSHPNAGPLATEADRVIQRTNSMQQLEQWIKVQKGRGLEEEPRGVISYQTLPRNMPSHRAQILARCPEGYRTLPRNSKTRPESICSVTSSGHEKTGPGAEEKRRSMRDDTMWQLYEWQQRQFYHKQSTLPRHGCLSSPKAMVQVSDQTMHSIPTSPSHGSAAAYQGFSPQRTYRSEVTSPIQRGDVTIDRRHRPHHPKHVYVADRRSMPAGLTLQAVSPQSLQGRTPEELTLLLIKLRRQQAELSSVREHTLAQLMQLKLEAHSPKNEILSHHLQRNTIYLDHQLSQDECRGTLYKYRPEEAGIDAKLSRLCEQDKVVRALEEKLQQLHKEKYTLEQALLSASQEIEMNADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRDQMQGQLDRLGEVQSESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGSSETGLAGSKPFSSVKYKSEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSETEAPVVKGSHFPVGVPLRTKSPTPESSTIASYVTLRKTKKMVELRTERPRSAVEQLCLAESARPRMTVEEQLERIRRHQQACLREKKKGLSVLGASDPSDVRDSPLRLT