wanglab/gogpt-training-data huggingface dataset:
Protein: E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147) (Q61510)
Organism: Mus musculus (Mouse)
Function: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of RIGI and IFIH1 (By similarity). Mediates 'Lys-63'-linked polyubiquitination of the RIGI N-terminal CARD-like region and may play a role in signal transduction that leads to the production of interferons in response to viral infection (By similarity). Mediates 'Lys-63'-linked polyubiquitination of IFIH1 (By similarity). Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs (By similarity). Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (By similarity). Plays a role in promoting the restart of stalled replication forks via interaction with the KHDC3-OOEP scaffold and subsequent ubiquitination of BLM, resulting in the recruitment and retainment of BLM at DNA replication forks.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q14258}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q14258}. Nucleus {ECO:0000269|PubMed:29125140}. Note=Localized to DNA replication forks. {ECO:0000269|PubMed:29125140}.
Interaction partners:
- Antiviral innate immune response receptor RIG-I
- Ubiquitin/ISG15-conjugating enzyme E2 L6
- Interferon-induced helicase C domain-containing protein 1
- Ubiquitin-conjugating enzyme E2 N
- Mitochondrial antiviral-signaling protein
- Interferon-induced, double-stranded RNA-activated protein kinase
- Ubiquitin-like modifier-activating enzyme 7
- Interferon regulatory factor 3
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-like protein ISG15
Sequence:
MAELNPLAEELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQVRPQLQKNTVMCAVVEQFLQAEQARTPVDDWTPPARFSASSAATQVACDHCLTEIAVKTCLVCMASFCQEHLRPHFDSPAFQDHPLQSPIRDLLRRKCTQHNRLRELFCPEHGECICHICLVEHKTCSPTTLSQASADLEYKLRNKLTIMHSHINGATKALEDVRSKQQCVQDSMKRKMEQLRQEYMEMKAVIDAAETSSLRKLKEEEKRVYGKFDTIYQVLVKKKSEMQKLKAEVELIMDKGDEFEFLEKAAKLQGESTKPVYIPKIDLDHDLIMGIYQGAADLKSELKHSIKKLQKKSEEHNGSGNKGDQTQSTFKPVQPSKKTIQEKKTKKTPVAPGPPSHFSPNKLPTFGAPGQSLDSKATSPDAAPKASAAQPDSVGVKAKVLENFLTKSRTELLEYFVKVIFDYNTAHNKVSLSNKYTTASVSDGLQHYRSHPQRFTYCSQVLGLHCYKNGIHYWEVELQKNNFCGVGICYGSMERQGPESRLGRNPNSWCVEWFNNKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVTEKVHLMYKFKVDFTEALYPAFWVFSAGTTLSICSK
Protein: Epsin-1 (Q12518)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Negatively regulated via phosphorylation.
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Note=Localizes in a punctate pattern. Found in the actin cortical patches.
Interaction partners:
- EH domain-containing and endocytosis protein 1
- Protein SLA2
- Actin cytoskeleton-regulatory complex protein PAN1
- Clathrin heavy chain
- AP-2 complex subunit alpha
- Actin cytoskeleton-regulatory complex protein END3
- Clathrin light chain
- Clathrin coat assembly protein AP180A
- Epsin-2
- Clathrin coat assembly protein AP180B
Sequence:
MSKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAEKSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYIIKTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNEERNMNIKGRNRKGRRRRGTGRSDENDDDLQRAISASRLTAEEDERRRKQDEDYETALQLSKEEEELKRLQDLQRMQQQQGQQQLQQPMYYDIFGNPITPEEYAQFQLQQQQQQQQQQLQQQPMYYDVFGNPITPEELAQFQQQQQLQEQQYLASMQQQQQAMSNNPFAKSEQSSSSPKRNQLVAASSPQQLQQQKQQEPLIQNRTGNQSMTDKYSKLNELLATGTGIDTFGNVGEARIPAQHTKTGTFINSQGTGYRQVSDDPNHNPFLNSQYTGLPSTSVVPTQTGYGFGNQSQQQSQNNGSNNRGYTLIDL
Protein: Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (B4DP46)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVITRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL
Protein: gamma-glutamylcyclotransferase (EC 4.3.2.9) (Q9VVP9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform B
- Microsomal glutathione S-transferase 1
Sequence:
MNYECLIGVLSCLLVALPKGNCHSISGLNSTLNLPEIRGDQFLYFGFGSNMLIKRIHIQNPSAVRIGPALLPDYRLDFALESAGWSGSVATIVPTQGDHVWGTLWKIDLSNLPDIDSQEGVSQGIYEPRTVYVKLHGESESTPARAYLLTKQPESNLYELPKDSIPLSRQPSKTYLQCLVKGAIESSVPEDYVQRLRSIKHNGQVNSYLERKLELGGVTL
Protein: DNA-directed RNA polymerase II subunit RPB7 (Q9VFB5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerase II subunit RPB2
- Transcription elongation factor SPT5
Sequence:
MFYHISLEQEILLHPRYFGPQLLETVKQKLYSEVEGTCTGKYGFVIAVTTIDQIGSGVIQPGQGFVVYPVKYKAIVFRPFKGEVLDAVVKQINKVGMFAEIGPLSCFISHHSIPADMQFCPNGNPPCYKSKDEDVVISGEDKIRLKIVGTRVDATGIFAIGTLMDDYLGLVSN
Protein: Dachshund homolog 1 (Dach1) (Q9UI36)
Organism: Homo sapiens (Human)
Function: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:14525983}.
Interaction partners:
- Protein phosphatase EYA1
- Homeobox protein SIX1
- Mothers against decapentaplegic homolog 4
- Homeobox protein SIX6
- Dachshund homolog 2
- Protein phosphatase EYA2
- Paired box protein Pax-3
- Transcription factor Jun
- Myogenic factor 5
- Homeobox protein SIX4
Sequence:
MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNASSRPGRPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSDGSWDKETLPSSPSQGPQASITHPRMPGARSLPLSHPLNHLQQSHLLPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPKEGDLAGHDMGHESKRMHIEKDETPLSTPTARDSLDKLSLTGHGQPLPPGFPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDSLRVLNDSLTPEIEADRSGGRTDAERTIQDGRLYLKTTVMY
Protein: Protein DETOXIFICATION 14 (AtDTX14) (Multidrug and toxic compound extrusion protein 14) (MATE protein 14) (Q9C994)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein DETOXIFICATION 44, chloroplastic
- Probable pectinesterase/pectinesterase inhibitor 59
- Probable pectinesterase/pectinesterase inhibitor 60
- Protein DETOXIFICATION 46, chloroplastic
- Probable folate-biopterin transporter 4
- At2g34355
- Major facilitator superfamily protein
- Major facilitator superfamily protein
- Protein DETOXIFICATION 42
- Pectin lyase-like superfamily protein
Sequence:
MDSAEKGLLVVSDREEVNKKDGFLRETKKLSYIAGPMIAVNSSMYVLQVISIMMVGHLGELFLSSTAIAVSFCSVTGFSVVFGLASALETLCGQANGAKQYEKLGVHTYTGIVSLFLVCIPLSLLWTYIGDILSLIGQDAMVAQEAGKFATWLIPALFGYATLQPLVRFFQAQSLILPLVMSSVSSLCIHIVLCWSLVFKFGLGSLGAAIAIGVSYWLNVTVLGLYMTFSSSCSKSRATISMSLFEGMGEFFRFGIPSASMICLEWWSFEFLVLLSGILPNPKLEASVLSVCLSTQSSLYQIPESLGAAASTRVANELGAGNPKQARMAVYTAMVITGVESIMVGAIVFGARNVFGYLFSSETEVVDYVKSMAPLLSLSVIFDALHAALSGVARGSGRQDIGAYVNLAAYYLFGIPTAILLAFGFKMRGRGLWIGITVGSCVQAVLLGLIVILTNWKKQARKARERVMGDEYEEKESEEEHEYIS
Protein: Uncharacterized oxidoreductase YIR035C (EC 1.-.-.-) (P40579)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Exosome complex component CSL4
- UPF0744 protein YSC83
Sequence:
MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANEERQVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYAKLALHGIPDGVNGQYLSYNDPALADFMP
Protein: Coenzyme A biosynthesis bifunctional protein CoaBC (DNA/pantothenate metabolism flavoprotein) (Phosphopantothenoylcysteine synthetase/decarboxylase) (PPCS-PPCDC) [Includes: Phosphopantothenoylcysteine decarboxylase (PPC decarboxylase) (PPC-DC) (EC 4.1.1.36) (CoaC); Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (CoaB) (Phosphopantothenoylcysteine synthetase) (PPC synthetase) (PPC-S)] (P9WNZ1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity). Required for growth and persistence in mice.
Interaction partners:
- Phosphopantetheine adenylyltransferase
- Pantothenate kinase
- Dephospho-CoA kinase
- Guanylate kinase
- Type III pantothenate kinase
- Pantothenate synthetase
- DNA-directed RNA polymerase subunit omega
- O-acetylserine sulfhydrylase
- L-cysteine desulfhydrase Cds1
- cysteine-S-conjugate beta-lyase
Sequence:
MVDHKRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSGEPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLARAAAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIAGHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIKKGVEGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLRRKGCDLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAIVTFLAGCSS
Protein: Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Q9D0F6)
Organism: Mus musculus (Mouse)
Function: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Replication factor C subunit 1
- Replication factor C subunit 3
- Replication factor C subunit 4
- Replication factor C subunit 2
- Cell cycle checkpoint protein RAD17
- Chromosome transmission fidelity protein 18 homolog
- Proliferating cell nuclear antigen
- Chromosome transmission fidelity protein 8 homolog
- Sister chromatid cohesion protein DCC1
- ATPase family AAA domain-containing protein 5
Sequence:
MTAAAPSQQRPAAARARNLPWVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKTDIANILDWMLNQDFTTAYKNIMELKTLKGLALHDILTEVHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAEA
Protein: Splicing factor Cactin (G5EG14)
Organism: Caenorhabditis elegans
Function: Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity). Plays a role during early embryonic development. Required for the distal tip cell migration at the end of larval development and for gonad morphogenesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:20188721}. Cytoplasm {ECO:0000269|PubMed:20188721}.
Interaction partners:
- Pre-mRNA-processing factor 17
- Coiled-coil domain-containing protein 12
- Pre-mRNA-splicing factor CWC22 homolog
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5
- PWI domain-containing protein
- RNA helicase
- Nuclear speckle splicing regulatory protein 1 homolog
- Replication stress response regulator SDE2
- Peptidyl-prolyl cis-trans isomerase
- STING ER exit protein
Sequence:
MGKDSKKHKKERRRERSPSTSDSDEERLQKRLAEQRSLKKDEKRRQKEEMKKNESAEEKRARRMEKKMRKDAKRKDADAEDTLIPPELNYTNLNNPFNDTKLTQTFVWGKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAKAIDLLSRYARFADENPHTAKIPDFELENPMEYLKASCKSVDDYEDLIEDIKTYREVDGWAKNETWWMDVTRIAEDEIQKKAAQNRGDVHASVQTEVQNMFKNKSIDELLKLEDQMDAKIRGNSGNKGYWQDLDDQLKVFIARKRLREHHGRVLRLQLAIIKEEQKKEIQQQESEELLPVAEVPPQVKIQKEEEEEEEEDEDDEKISKKVRRKIDVQTLDDPELDEPERERKWRALTGDQLDDVTRELYRIGCYSPTYISADDTMPGIEILDEQADVDNLTERRNRNRGTLPSSSAASSGAPQGASSKMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPDFAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR
Protein: proton-translocating NAD(P)(+) transhydrogenase (EC 7.1.1.1) (A0A8I6ADT1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAHLLKTVVTGCLCPSVSNLGSCKVLPGKKDFLRTFRTHQALWCKSPAKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFPDDLYRAAGAQIQGTKEVLASDLVVKVRAPMVNPTLGAHEADFLKPSGTLISFIYPAQNPDLLNKLSERKTTVLAMDQVPRVTIAQGYDALSSMANISGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAVVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGLAIAKRIQISDLPQLVAAFHSLVGLAAVLTCMAEYIVEYPHFAMDATSNFTKIVAYIGTYIGGVTFSGSLVAYGKLQGILKSAPLLLPGRHALNAGLLAASVGGIIPFMADPSFTTGIMCLGSVSALSTLMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAVEMIREANSIVITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINSDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK
Protein: Phosphomannomutase 2 (PMM 2) (EC 5.4.2.8) (O15305)
Organism: Homo sapiens (Human)
Function: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Subcellular location: Cytoplasm.
Interaction partners:
- Mannose-6-phosphate isomerase
- Mannose-1-phosphate guanylyltransferase regulatory subunit alpha
- Phosphomannomutase 1
- Mannose-1-phosphate guanylyltransferase catalytic subunit beta
- Hexokinase-1
- Alpha-1,3/1,6-mannosyltransferase ALG2
- Hexokinase-3
- Hexokinase HKDC1
- Hexokinase-2
- Glucose-6-phosphate isomerase
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
Protein: Zinc finger protein BALDIBIS (ID1-like zinc finger protein 1) (Protein indeterminate-domain 9) (Q944L3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that, together with JKD, regulates tissue boundaries and asymmetric cell division in roots by a rapid up-regulation of 'SCARECROW' (SCR), thus controlling the nuclear localization of 'SHORT-ROOT' (SHR) and restricting its action. Confines CYCD6 expression to the cortex-endodermis initial/daughter (CEI/CEID) tissues. Binds DNA via its zinc fingers. Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Interaction partners:
- GATA transcription factor 11
- C2H2 and C2HC zinc fingers superfamily protein
- C2H2-like zinc finger protein
- C2H2-like zinc finger protein
- B3 domain-containing protein REM6
- Protein SIEL
- Zinc finger
Sequence:
MMMPDDHHPLSFPSYVLHQEHIAPNPNPNPNPTSSNSAKRKRNLPGNPDPDAEVIALSPNSLMTTNRFICEVCNKGFKRDQNLQLHRRGHNLPWKLKQRTNKEQVKKKVYICPEKTCVHHDPARALGDLTGIKKHFSRKHGEKKWKCDKCSKKYAVMSDWKAHSKICGTKEYRCDCGTLFSRKDSFITHRAFCDALAEESARFVSVPPAPAYLNNALDVEVNHGNINQNHQQRQLNTTSSQLDQPGFNTNRNNIAFLGQTLPTNVFASSSSPSPRSASDSLQNLWHLQGQSSHQWLLNENNNNNNNILQRGISKNQEEHEMKNVISNGSLFSSEARNNTNNYNQNGGQIASMSATALLQKAAQMGSKRSSSSSSNSKTFGLMTSIFNNKQAENIKTKEVDERGFTRDFLGVGSQHRSWPLLMVNHNLPDSSPPASTDGTPTADMNQ
Protein: Chromatin assembly factor 1, p180 subunit (Chromatin assembly factor-1 p180 subunit) (Q9W3D1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Chromatin assembly factor 1, p105 subunit
- Chromatin assembly factor 1 p55 subunit
- Histone chaperone asf1
- DNA replication licensing factor Mcm5
- DNA replication licensing factor Mcm2
- DNA polymerase alpha catalytic subunit
- DNA replication licensing factor Mcm3
- DNA replication licensing factor MCM4
- Heterochromatin protein 1
- Proliferating cell nuclear antigen
Sequence:
MHAGVVKTPLSGRKKDAAVPAKSAEKTASGGKKFVQTRLPFKLLTPGGGAVPTSSSSSSSPATIGSGPVTVILDEDDPAPRKRKLSYDDESPSEGTGCSTGQLRRSTSKENLDLASSIATKKVKTTDSVVEDVIELDEDEADKEIEDQDQLVEAKSSKEVKLKPKKSEGKKGSPAPIQIKLPLVNKRSKRRKSLKKSEEPLETSTADVAKGDSESSDDIEIIAEELNPQKRQKVQTPREKSPENSSTSGKHTEEVMQKNGKDSKKQEESMKAVKESKKEEPKTAEQNKKNDQATIDLFMGKKMETNKKDKPEVKTTAKDNKKDPLIAEDSKPKEVPKKETSKTGGKGKKEGAKPAEKSKKEEKEDSTTKSKKEKADSPANNQKEQQIGVKKKTSEPEDASNSHKSVTAKKDSKKDEASTQVKSDNESPEAAEISMILSTSEANSSSSEHEMDADTDTAATDRPSAQKETRLNRKSLPEVTGAPKGLTPKQQRLMEQRKKAREEKEQKLAEERRLKQQDKEHREQQKKQERDEKEQQRKLERDQKEQQRKMEKEEKERKRQAEVDSKNEEKRKRNEAKEEVQRKKDEERRKKEQEREEAEQKKKRAAESFSKFFVPKQPKCGSGSNNTSYLEHEQSSCDSSKASSQTLAFRPFQIKDDMLLAPIVRNSLGQEQRSQLDGLFRHRDEEADDEEEEEEQDIVRRKPPNRANLYLSELSSGRRKPLKMQRDVKLQRRTKDEEDDDDVQVIDYLSPAGLPIEVEQPKQLTRMKAKYLHFADNRRPPYYGTWRKKSSSISARRPLAQDKVLFDYEVDSDCEWEEEEPGESLSASEDEKEKESEEESEEEYNEWYVPHGHLSDEELQNDGDGMEDGHTREAQKAKLQVLQQEFAQEMKKQTKKIKARLLGPVWLDENGNKSELFPAIFAHTIDMYACWQVEPLSLEPPPEPERQDQTPEQPVPLQLDDRLMQQLVRLTHGNRNSKTFLINEYLEYLKTQATAEANQTTLPSKAVLREKFDELASWKTVELSTPEAAAASANSAKKGRKPKKRLCWVVASDMLEKFQLPDLQLQNQWNYTLTPKVSDGPDAAQQEQSPPADAVPAASPASNQTTNSAPTTPISGQTQAGQGVKKRATLIMSVPRDQPIPSATKNKLISQFLQRQSDASKPKEKMQEKPPPIVFDDVVMLSD
Protein: Solute carrier family 4 (anion exchanger), member 1, adaptor protein (A0A0J9YTU2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
XVLSEPSSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIPELKKTELQTTNAENKTKKLALPLFGAMKGGSKFKLKTGTVGQHQRMNINKTEMSRRKRNLLGLANFHPSFLPNILRMTQTTVYGSHLKVKVEMAEPILMTSMATDWLRVPKEDHVDRRMFGRKHQVMARNQMTVCKIW
Protein: Thiosulfate sulfurtransferase YnjE (EC 2.8.1.1) (P78067)
Organism: Escherichia coli (strain K12)
Subcellular location: Periplasm {ECO:0000305}.
Interaction partners:
- TVP38/TMEM64 family inner membrane protein YdjZ
- Protein YnjB
- Cysteine desulfurase IscS
- Uncharacterized protein YdjY
- TVP38/TMEM64 family membrane protein YdjX
- Inner membrane ABC transporter permease protein YnjC
- Uncharacterized ABC transporter ATP-binding protein YnjD
- Uncharacterized protein YnjA
- Molybdopterin synthase sulfur carrier subunit
- Molybdopterin-synthase adenylyltransferase
Sequence:
MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAIDTRPSAFYNGWPQTLNGPSGHELAALNLSASWLDKMSTEQLNAWIKQHNLKTDAPVALYGNDKDVDAVKTRLQKAGLTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEVTAKPAGDWKVIEAAWGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKHGIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKVKAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGEIAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPEQQVSFYCGTGWRASETFMYARAMGWKNVSVYDGGWYEWSSDPKNPVATGERGPDSSK
Protein: Peroxidase 54 (Atperox P54) (EC 1.11.1.7) (ATP29a) (Q9FG34)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000305}. Vacuole {ECO:0000305}. Note=Carboxy-terminal extension appears to target the protein to vacuoles.
Interaction partners:
- PLC-like phosphodiesterases superfamily protein
- Sulfite exporter TauE/SafE family protein 2
- Receptor protein kinase-like protein
- Berberine bridge enzyme-like 7
- AT3g19030/K13E13_15
- DUF21 domain-containing protein At5g52790
- WAT1-related protein At4g01440
- GRAS family transcription factor family protein
- RING-H2 finger protein ATL11
- Cytochrome b-c1 complex subunit 7-2, mitochondrial
Sequence:
MAVTSSSSTCDGFFIISLIVIVSSLFGTSSAQLNATFYSGTCPNASAIVRSTIQQALQSDARIGGSLIRLHFHDCFVNGCDGSLLLDDTSSIQSEKNAPANANSTRGFNVVDSIKTALENACPGIVSCSDILALASEASVSLAGGPSWTVLLGRRDGLTANLSGANSSLPSPFEGLNNITSKFVAVGLKTTDVVSLSGAHTFGRGQCVTFNNRLFNFNGTGNPDPTLNSTLLSSLQQLCPQNGSNTGITNLDLSTPDAFDNNYFTNLQSNNGLLQSDQELFSNTGSATVPIVNSFASNQTLFFEAFVQSMIKMGNISPLTGSSGEIRQDCKVVNGQSSATEAGDIQLQSDGPVSVADM
Protein: Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial (EC 1.1.5.3) (Protein SUGAR-DEPENDENT 6) (Q9SS48)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for glycerol catabolism and involved in NADH/NAD(+) homeostasis. Essential for postgerminative growth and seedling establishment.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:12586344}; Peripheral membrane protein {ECO:0000305|PubMed:12586344}.
Interaction partners:
- Glycerol kinase
- Glycerol-3-phosphate dehydrogenase [NAD
- Dihydroxyacetone kinase
- Glycerol-3-phosphate dehydrogenase [NAD
- Putative lipid phosphate phosphatase 3, chloroplastic
- Triacylglycerol lipase SDP1
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate acyltransferase 9
- Probable glycerol-3-phosphate acyltransferase 8
Sequence:
MSLASIRRLAAGAAVIAAASGGAVYLSPSVASSDKGGGPILDSLRRRLGDPTASVPSRSAQESALIAATASDPLDVLVIGGGATGSGVALDAVTRGLRVGLVEREDFSSGTSSRSTKLIHGGVRYLEKAVFNLDYGQLKLVFHALEERKQLIENAPHLCHALPCMTPCFDWFEVIYFWMGLKMYDLVAGPRLLHLSRYYSAKESIELFPTLARKGKDKNLRGTVVYYDGQMNDSRLNVGLACTAALAGAAVLNHAEVVSLITDDATKRIIGARIRNNLTGQEFNSYAKVVVNAAGPFCDSIRKMIDEDTKPMICPSSGVHIVLPDYYSPEGMGLIVPKTKDGRVVFMLPWLGRTVAGTTDSNTSITSLPEPHEDEIQFILDAISDYLNIKVRRTDVLSAWSGIRPLAMDPTAKSTESISRDHVVFEENPGLVTITGGKWTTYRSMAEDAVDAAIKSGQLKPTNECVTQKLQLLGSYGWEPSSFTTLAQQYVRMKKTYGGKVVPGAMDTAAAKHLSHAYGSMADRVATIAQEEGLGKRLAHGHPFLEAEVAYCARHEYCESAVDFIARRCRIAFLDTDAAARALQRVVEILASEHKWDKSRQKQELQKAKEFLETFKSSKNAQFNDGKHN