wanglab/gogpt-training-data huggingface dataset:
Protein: Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (CLM1) (SEC7 homolog A) (mSec7-1) (Q9QX11)
Organism: Mus musculus (Mouse)
Function: Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18042453, ECO:0000269|PubMed:29420262}; Peripheral membrane protein {ECO:0000269|PubMed:18042453}. Cytoplasm, cytosol {ECO:0000269|PubMed:18042453, ECO:0000269|PubMed:29420262}. Cell junction, tight junction {ECO:0000269|PubMed:20080746}. Cell junction, adherens junction {ECO:0000269|PubMed:20080746}. Note=Colocalized with TJP1 during epithelial polarization (PubMed:20080746). {ECO:0000269|PubMed:20080746}.
Interaction partners:
- ADP-ribosylation factor 6
- ADP-ribosylation factor 1
- ADP-ribosylation factor 2
- Cytohesin-interacting protein
- FERM domain-containing protein 4B
- FERM domain-containing protein 4A
- Guanine nucleotide exchange factor MSS4
Sequence:
MEDDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
Protein: FI18641p1 (Gliotactin, isoform A) (Gliotactin, isoform C) (Gliotactin, isoform D) (Gliotactin, isoform E) (Gliotactin, isoform F) (Q7KT70)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Protein hedgehog
- Protein smoothened
- Protein patched
- Suppressor of fused homolog
- Kinesin-like protein costa
- Protein HIRA homolog
- Disks large 1 tumor suppressor protein
- Neurexin-4
- Protein decapentaplegic
- Interference hedgehog
Sequence:
MMHKLKYRDKLKWLLALLVLIGTCFIQTRGQTRDPRFYSRPGVDYHWPNPGDPDYRTYTFNDRRYGHYQPNGYGANYPGRNPPGQYPQGMPNEDRFRFDPNDPNARTQFPGVLAGWREDLQGKQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVIGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVACFFLIVLVVICCIMWRNAKRQSDRFYDEDVFINGEGLEPEQDTRGVDNAHMVTNHHALRSRDNIYEYRDSPSTKTLASKAHTDTTSLRSPSSLAMTQKSSSQASLKSGISLKETNGHLVKQSERAATPRSQQNGSTAKVASPPVEEKRLLQPLSSTPVTQLQAEPAKRVPTAASVSGSSRSTTPVPSARSTTTHTTTATLSSQPAAQPRRTHLVEGVPQTSV
Protein: Magnesium-chelatase subunit ChlD, chloroplastic (Mg-chelatase subunit D) (EC 6.6.1.1) (Mg-protoporphyrin IX chelatase subunit ChlD) (Protein ALBINA 1) (Protein PIGMENT DEFECTIVE EMBRYO 166) (Q9SJE1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. The magnesium-chelatase is a complex of three subunits, CHLI, CHLD and CHLH. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step. Does not bind abscisic acid.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Magnesium-chelatase subunit ChlH, chloroplastic
- Magnesium protoporphyrin IX methyltransferase, chloroplastic
- Protoporphyrinogen oxidase 1, chloroplastic
- Protoporphyrinogen oxidase 2, chloroplastic/mitochondrial
- Ferrochelatase-1, chloroplastic/mitochondrial
- Magnesium-chelatase subunit ChlI-1, chloroplastic
- Tetrapyrrole-binding protein, chloroplastic
- Magnesium-chelatase subunit ChlI-2, chloroplastic
- Chlorophyll synthase, chloroplastic
- Ferrochelatase-2, chloroplastic
Sequence:
MAMTPVASSSPVSTCRLFRCNLLPDLLPKPLFLSLPKRNRIASCRFTVRASANATVESPNGVPASTSDTDTETDTTSYGRQFFPLAAVVGQEGIKTALLLGAVDREIGGIAISGRRGTAKTVMARGLHEILPPIEVVVGSISNADPACPDEWEDDLDERIEYNADNTIKTEIVKSPFIQIPLGVTEDRLIGSVDVEESVKRGTTVFQPGLLAEAHRGVLYVDEINLLDEGISNLLLNVLTDGVNIVEREGISFRHPCKPLLIATYNPEEGAVREHLLDRVAINLSADLPMSFEDRVAAVGIATQFQERCNEVFRMVNEETETAKTQIILAREYLKDVKISREQLKYLVLEAVRGGVQGHRAELYAARVAKCLAAIEGREKVTIDDLRKAVELVILPRSSLDETPPEQQNQPPPPPPPPQNSESGEEENEEEQEEEEEDESNEENENEQQQDQIPEEFIFDAEGGLVDEKLLFFAQQAQKRRGKAGRAKNVIFSEDRGRYIKPMLPKGPVKRLAVDATLRAAAPYQKLRREKDISGTRKVFVEKTDMRAKRMARKAGALVIFVVDASGSMALNRMQNAKGAALKLLAESYTSRDQVSIIPFRGDAAEVLLPPSRSIAMARNRLERLPCGGGSPLAHGLTTAVRVGLNAEKSGDVGRIMIVAITDGRANITLKRSTDPESIAPDAPRPTSKELKDEILEVAGKIYKAGMSLLVIDTENKFVSTGFAKEIARVAQGKYYYLPNASDAVISATTRDALSDLKNS
Protein: Protein-serine/threonine kinase (EC 2.7.11.-) (D6RDN9)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000256|RuleBase:RU366032}.
Interaction partners:
Sequence:
MKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPGTGGTPL
Protein: Ataxin 7 (Ataxin-7 isoform X1) (E7F640)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 22
- Transcriptional adapter 3
- Transcription initiation factor TFIID subunit 10
- Transformation/transcription domain-associated protein
- Transcription initiation factor TFIID subunit 9
- Histone acetyltransferase KAT2A
- Transcriptional adapter 2-beta
- Transcription and mRNA export factor ENY2
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 6
Sequence:
MSERADDDVRGEQQQQQRRAARQLKQQPHFQRGEASTAMATVAERRSLPSPEIMLGQPWSSWVDAVKLYGSDGTELEESLKECGKNREAMRLCRDDMPIFGQCPAQDDFYLVMCSHCSQVVKPQAFQAHYERRHSSSSKPPSSYASSPAFANSRSKGSLGGSGSTLARPSSANSSVPTKIFKSTKEKLPHRKPHFPFRVPSEESQIPTVKVEKVHLKVESSAKLPHVPASSSTFSSSSSSSNTVSTSPLKSGLNFPSIPKAPQLAPGQIPNGKGHQSSQDKKQDNASSRRPLYKRQEREFNPDIHCGVMDMTARKPCTRSLTCKSHSISQRRAVLGRRQRFDTLLAEHKSKTRDKELQFRLDPSHPAPPLRDPHPPPSRLSQDPHPVPHGNGTADATKPLPPNKPKPHNSGLPRINSSNSHSGGDPAMAHDQAHHSHPAPVGPETSRVSSDEGENEDREEATEKLDCHYSGYHPRPAAYCTFGSRLYGRGCFAFDRRWDQVRCALTTMLDKHVNSQMWKKIPLALENSTTAPSASHRTSTNSHSSSSSSVSSGFLGLSSPPPYDSKPVLSYGTTLNARSSPQASATEQPAYSGSSRQVSASSPQMPSAHSSSLPSLGSNRTPKSRSGTKSFRAREPSSSLSNSIIKGSTNSSVSVSSSASSSLSAGKKRKTSSLLTSHSTYTSESSSSFKKNCTINSGSVGSAYHSSLASTPSSTSSSSSTTSSSHSGVYSVGVNCTPGRANSLSLKQESTGRGPPSGSPAESIKRMSVVMNSSDSTLSLGPFVHQSSDHHTDARLEAKRRKGSPGSSSLNSTASGTGVGGGQGPGRPKMAKSPSINNIHSKHARSIPGPPGLPNNSLIHQPKARP
Protein: Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) (Q9UBR2)
Organism: Homo sapiens (Human)
Function: Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides (By similarity).
Subcellular location: Lysosome.
Interaction partners:
- Apoptosis regulator Bcl-2
- Bcl-2-like protein 1
- BH3-interacting domain death agonist
- Angiotensinogen
- Melanocortin receptor 3
- ATP synthase F
- Protein ERGIC-53
- Legumain
- Cathepsin D
- Tubulin beta-1 chain
Sequence:
MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIV
Protein: PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1) (O75626)
Organism: Homo sapiens (Human)
Function: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (By similarity). Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:28842558}. Cytoplasm {ECO:0000269|PubMed:21421998}.
Interaction partners:
- Signal transducer and activator of transcription 3
- Interferon regulatory factor 4
- Histone-lysine N-methyltransferase EHMT2
- Paired box protein Pax-5
- Histone deacetylase 2
- Cellular tumor antigen p53
- X-box-binding protein 1
- Protein arginine N-methyltransferase 5
- Syndecan-1
- Transcription regulator protein BACH2
Sequence:
MLDICLEKRVGTTLAAPKCNSSTVRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP
Protein: Moesin/ezrin/radixin homolog 1 (Ezrin-moesin-radixin 1) (Moesin) (dMoesin) (Protein D17) (P46150)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles.
Subcellular location: Cell junction, adherens junction {ECO:0000269|PubMed:8666669}. Cell projection, microvillus {ECO:0000269|PubMed:8666669}. Cell projection, rhabdomere {ECO:0000269|PubMed:8666669}. Cell membrane {ECO:0000250|UniProtKB:P26041}; Peripheral membrane protein {ECO:0000250|UniProtKB:P26041}; Cytoplasmic side {ECO:0000250|UniProtKB:P26041}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P26041}. Cytoplasm {ECO:0000269|PubMed:28554770}. Cytoplasm, cell cortex {ECO:0000269|PubMed:24768049}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:20237161}. Nucleus, nucleoplasm {ECO:0000269|PubMed:28554770}. Chromosome {ECO:0000269|PubMed:28554770}. Note=Nuclear localization is dependent on Nup98 and Rae1. Associated with the active ecdysone-regulated loci on polytene chromosomes and heat shock-induced puffs. Colocalizes with messenger ribonucleoprotein (mRNP) particles probably through interaction with the mRNA export factor PCID2 (PubMed:28554770). Localizes to the apical cell cortex of follicular epithelium cells when phosphorylated on Thr-559 (PubMed:24768049). Localizes to ring canal structures at the growing end of elongating spermatid cysts when phosphorylated on Thr-559 (PubMed:20237161). {ECO:0000269|PubMed:20237161, ECO:0000269|PubMed:24768049, ECO:0000269|PubMed:28554770}.
Interaction partners:
- Protein crumbs
- Patj homolog
- Atypical protein kinase C
- Protein PALS1
- LD29223p
- Protein lin-7 homolog
- Zyx102 protein
- Protein limb expression 1 homolog
- Exocyst complex component 2
- Cadherin-86C
Sequence:
MSPKALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNKTTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEDARRKQVIAAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIEDRRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM
Protein: Erythrocyte membrane protein 1, PfEMP1 (Q9U0G5)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MGPPSTAPDYSSAKDAKDLLDMIGKDVHDQVEKEAAGRGGSELKGLLSLAKGSGVELAAFPEPCGLIKDKGDELLGDSGERHPCGNTTGKEDVDRFSVKQQAEYDNKKMKCSYGSNGTDVGACAPYRRLFLCNKNMEKMGRTSTTKHDLLLDVCMAANYEAQSLIRYHDKHQLTNEGSQICTVLARSFADIGDIIRGKDLYLGKKKKKKTETERDQLESKLKKIFGDIYNELTNGRNGVKDHYQDDNGGNYFQLREDWWTANRATVWKAITCKADTGNAYFRPTCSDSDGKGSFSQANDKCRCKDKKGKNTDQVPTYFDYVPQYLRWFEEWAEDFCRKKKIYVGIVKTYCREKYKSGNEPRYCSRNGYDCTKTKRAIGKYRMGNQCISCLYACNPYVDWINNQKEQFDKQKQKYDKEIKIYKNGASGIRRQKRGTTTKYEGYEKKFYDKLEKNNYGTVGEFLGLLNNEKACKEVKDGGTIDFKQVNSTSGGTAVSASGASSTSGGSGAASGGTSDTSGTNNASQGTFYRSEYCQPCPHCGVRKANNGNFVKKSDSEQCKNINLYRPKKPEEGTKIEILKSGEGETEIKEKLEQFCQTQNATGGVANGSGSGTSGSQKLYEDWKCYNDVEKDGQDGVDDDDDLEYDRLVNSSGGLCILQKKNGEENGKKQKTYNDFFNFWVAHMLKDSIHWRTKKIKGCLKNGKAIKCTDKCKGDCKCFERWVEQKREEWTNIKEHFGKQTDIPTGLTPDALLEGVLEKGVLLTSIKEAYGDAKETEHIKQLLDETAVAGGVVVGAKDNTTIDKLLEQELKDANRCKNCEQRKPPGEEGGAARNLPGVDTTVDDANEDDLDDEDDEDEDDDGGGSDVGGSDVGEVEEETAKEATEETTTPLDVCNTVKTALEGDLGEACRQKYEYGREKFPNWKCISGDNTRGSESESAGPSRSKRHTESSDSAVTATGSSGEATGKSGDKDGAICVPPRRRKLYLGGFKRLTDGTAVSSEATQAGTPSQSPKGDALLLTAFVETAAVETFFLWHKYKQEKKKPKNEVGGAAGVLQTIGGTLENSGEQNPQKKLQESGEIPDDFLRQMFYTLGDYRDILVRGVADDKNGGNNIILNASGNKEDMEKMKKIQQEIDKILEKSGSEAASGAQKNSGISREKWWDKHAPSIWDGMVCALTYNTDTASGTAPTQIQEVKNALLDGEGKKPKQNGTNGKDYTYGGVRLEDENSGTQALSPNAPASTASQTTQSSSTSENTPTTLTNPKLKDFVLRPTYFRYLEEWGQNFCKERKKRLDQIYRECKVDEDGPRDGKKCSGYGEDCKDNLSKKYDTLPSLECPGCGRHCSFYKKWIKIKKDEYEKQQKAYNEQRTNYTNKNKVSESNNHDKEFCTNLETKYTDAANFLQRLKDGPCKNNSEEDQKVNGYIKFDDISKDKTFGHENYCDPCSKFTVNCNRNDHCDNSNGNNCKDNKITAEKIGNGVDSTVLDMRVIDDSATGFKGDGLEEACGSANIFKGIRKEQWKCGKVCGYNVCKPKEGNRETVRGEKNDDKHIITIRALVTHWVQNFLEDYKKIKHKISHCTKTDQGSTCQNKCQNKCKCVGEWIKLKQQEWEEIKKRFLNQYKMDSDEYYPVRSVLETFLVQIGAANANNDVKKLIKLSEFYKSCGCSAKTNSENNKNEDAIDCMLDKLGKKAEKCHDQHSDNPQEKCDEPPPELDEEDLLLEEEQNPKNMRPGFCPQNDTTEQQEEEENICTPAETVKKEEEEKEEQEEEEPDEKVPPPRAPEASKPKKEKPSQPPRPRRTLELLDNPHVQTALVTSTLAWSVGIGFAAFTYFYLKKKTKASVGNLFQILQIPKSDYDIPTLKSSNRYIPYASDRYKGKTYIYMEGDSSGDEKYAFMSDTTDVTSSESEYEELDINDIYVPGSPKYKTLIEVVLEPSGNNTPTSDIPSDIPNSDTPPPITDDEWNQLKKDFISNMLQNTQNTEPNILHDNVDNNTHPTMSRHNMDQKPFIMSIHDRNLFSGEEYNYDMFNSGNNPINISDSTNSMDSLTSNNHSPYNDKNDLYSGIDLINDALSGNHIDIYDEMLKRKENELFGTQHHPKNITSNRVVTQTSSDDPITNQINLFHKWLDRHRDMCEKWKNNHERLPKLKELWENETHSGDINSGIPSGNHVLNTDVSIQIDMDNPKTMNEFTNMDTNPDKSTMDTILDDLEKYNEPYYYDFYKHDIYYDVNDDKASEDHINMDHNKMDNNNSDVPTNVQIEMNVINNQELLQNEYPISHM
Protein: Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (Semaphorin-5A isoform X1) (F1R9L1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MAEGRPLARGLVLLHSLLLLMPRGVPCRGAIRALESPCHRAEHPLISHTDIEPWIHRFRAEGTVDYSQLTFDPGQNELIVGARNHLFRLHLEDLSLIQEAEWHCDEFTKGACFSRGKSEEECQNYIRVLLVNGDRLFTCGTNAFTPICTNRTLTNLTEVHDQISGMARCPYNPLHNSTALITSSGELYAATAMDFSGRDPAIYRSLGGLPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGRTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEIPFNYNELQGTFFLPELELLYGIFTTNVNSIAASAVCAFNLSAITQVFSGPFKYQENSRSAWLPYPNPNPDFQCGTIDFGSYVNLTERNLQDAQKFILMHEVVQPVVPVPYFMEDNVRFSHVAVDVVQGKDMLYHIIYLATDYGTIKKVLSPLNQTTGSCLLDEIELFPLKKRQPIRSLLILHSHSELFVGVREQVIKIPLMRCNFHKSREACVGARDPYCGWDLVLKKCTTLEESVSMSQWEQSITRCPVRNVTVDGHYGAWSGWKTCSHSDGGSVGSCQCRTRACDSPSPQCGGQPCQGISVEVANCSRNGAWTPWTAWAPCSTSCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLPCPPHVYWSAWSPWERCTVPCGGGIQSRRRTCENGNECPGCSTEFQSCNTLPCPDLKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARVPEPGLLEVGRQRIEMRYCSSDGSTGCSTDGDLLRSGRITGLTVNGGWSVWGPWSQCSRDCSSGVRNRKRTCSNPKPKYGGITCLGPAQEFQECNTTPCPVDGSWSCWSPWSKCSVTCGGGHYMRTRSCNNPPPAYGGDICLGLHTEEALCNIQPCPESWSDWSEWSPCDSSGSQVRLRHCDVLFPTGNQCSGNSSETRACLPISNFIPETSVARSSQEERWCGDFNVFHMIAVGLSSSILGCLVTLLVYTYCQRYQQQSHDATVIHPISAAPLNTSISNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPQLAGKTYTNAYFTDVNTYDDF
Protein: Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) (Q9NBX4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMPLRILVWNADGVSTKLPEVECFVRRHEIDVLLLSETHCKGAETPKLFGFVAYTANDPSGGNAKGGAAILIKNSLAHFPLTPIATAKVQLAPAVIETALGPISFGAVYCPPRFAWTTDEFKDILEEFQTKFIVAGDWNASHWLWGAGRSNQRGIALANLVLNSEVDSLATGGPTRYPYGCRGSPGYIDFALTKGVLGIHANISAVVELSSDHLPLVITLDAGAISYPKMERLITRRTNLEVFQSQLESTLPLNTAINSGQDVDDAIELLTNNIKSAARLATRSISRQPAADRIPIPREILLLIAEKRRLRTRWMRSRHPSDKTEWNRALSRLRCALVLHKAAWFDERLANTGVESEATHSLWKATRAIKRRCTRKAPLVDSNGTWCRTDLGQAEVFAAHLAERFQPFKLASLQQVEETQDQLNQALQMDMPITPFEPCEVAEVIVRQSNNKAPGHDVICNATLKALPRQAILYITLVFNAIVRLQYFPYQWKLGIISMIHKPGKPEREPASYRPISLLPSISKVFERLIAVRIVSIMEAQGITPEHQFGFRAGHCTVEQLHRVVEQILTAYDSKEYCNSLFLDIREAFDRVWHIGLQLKIKQTLPAPYFGLLKSYLEGRRFAVRFHSAISTEHNVAAGVPQGSVLGPLLYCLYSHDMPQPDVSLYGKSMLATFADDVCVTYRSRCEHDAADGIQDFAYRFSEWARRWNIGINSSKSNNVCFTLKRRTPPPVYIEEVPVPQPNAAKYLGVLLDRRLTFSKHVTDIRTRLRAKVAKHYWLLSSRSKLSLSNKLTIYKQILAPNWKYGCQIWGLACDSHIKRIQAIQNKVARLITGCEWFVRNTTLHRDLKLATVFDEINKHSSRYHDRLERHRNRLASALNRSRPPRRLNRRQPRDLITRSPLTRVRRS
Protein: T-protein [Includes: Chorismate mutase (CM) (EC 5.4.99.5); Prephenate dehydrogenase (PDH) (EC 1.3.1.12)] (P07023)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm.
Interaction partners:
- Bifunctional chorismate mutase/prephenate dehydratase
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
- Chorismate synthase
- Histidinol-phosphate aminotransferase
- Aromatic-amino-acid aminotransferase
- Anthranilate synthase component 1
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Bifunctional protein TrpGD
- 3-dehydroquinate synthase
- Aspartate aminotransferase
Sequence:
MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVVIVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNGPLQAMLVAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ
Protein: Probable polyketide synthase Pks8 (O65933)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable polyketide synthase Pks17
- Probable polyketide synthase Pks7
- Probable polyketide synthase Pks9
- Phenyloxazoline synthase MbtB
- Mycocerosic acid synthase-like polyketide synthase
- Phthioceranic/hydroxyphthioceranic acid synthase
- Probable multifunctional mycocerosic acid synthase membrane-associated Mas
- Phenolphthiocerol/phthiocerol polyketide synthase subunit C
- Mycoketide-CoA synthase
- Isonitrile lipopeptide synthase
Sequence:
MSGTTTHVDYLKRLTADLRRTRRRLSDLEAKLSEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADRGWDVDGLFDPDPDACGKMYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSATGVFAGVIHAGYGGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQDRVEPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSLLTQPRAWSVHGRPRRAGVSSFGISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSARSEQALAGQAQRLLAFVAANPDLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKTVFVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEFAQPALFAIEVALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMAELPAGGVMVVVAASEEEVLPVLVDGANLAAVNAPHSVVVSGCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHARRPVRFAEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVLGAVATLFTAGAQMDWPAVFGSPGRRIELPTYAFQRQRYWLPPTSAGSADISGVGLLAARHGLLGAVVEQPDSDVVVLTGRLSVGEQRWLADHVIAGVVLLAGAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGEMGQRPVSIYSRNAESDSGWVLHARGVLGAKAVAPAADLSVWPPLGAAPVDVDGAYQRFAELGYEYGRAFQGLTAMWRRESELFADVAVPDDVDVTLSGFGIHPLVLDAALHAMGMVGEQAATMLPFSWQGVSLHAAGASRVRARIAPAGDGTVSVELADQAGLPVLSVQALVMRSVSSQLLSAAVAAADAAGRGLLEVAWLPVELAHNDISADLVVWELESFQDGVGPVYSATHRVLVALQSWLAQERAGRLVVLTQGSVGQDATNLAGAAVWGLVRSAQAEHPGRVMLVDSDGSMDVGDVIGCGEEQLMIRNGTAYAARLAQLRPQPILQLPDTNSGWRLVAGGAGALEDLTLASCPAKELAPGQVRIEVRALGVNFRDVLVALGIYPGAAELGAEGAGVVTEVGPGVTGLAVGDPVMGLLGVAGSEAVVDARLVVKLPNRWPLTDAAGVPVVFLTAYYALRVLAQVQPGESVLVHAAAGGVGMAAVQLARLWGLEVFATASRGKWDTLHTMGCDNTHVADSRTLAFEETFWLTTEGRGVDVVLNSLAGEFTDASLRLLPRGGRFIEMGKTEFGTPRSLPRTILGWPTGLST
Protein: Col6a3 protein (Q80VJ0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MKPVTTTKPTAIVNLTPAKPAPARPAPAQPVLAKPDPAKPAQARPAPAKPASAKLVPPQPVHVQPAPAQTASVRPAPAKPAPPQPAAAKPVPAKPAVPAQPAPPQPAAAKPVPAKPAVPAQPAAAQPMPAQPVLTKSAAVKPASANKPVAAKPVATNTATATARPALAAKPAAAKPAATRPLAAAVRPVATKPEAPRQQAKPAATKPATTKPLARVSREVQVSEVTENSARLHWERPEPSSSFFYDLTVTSAHDQSLVLRQNLTVTDRVIGGLLAGQLYHVVVVSYLQSQVRAIYQGSFNTKKTQPPPLQAAHRASSSTINLMVNTEPLFLTKTDICKLSRHAGTCVDFKLLWHYDLESKSCKRFWYGGCGGNENRFHSQEECEKMCSPELTV
Protein: VAMP-like protein YKT61 (AtYKT61) (Geranylgeranylated protein 1) (AtGP1) (Q9ZRD6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the secretory pathway (By similarity). Essential for membrane fusion mediated by either SYP41 or SYP61; triggers the fusion of phospholipid vesicles containing SYP41 or SYP61 and VTI12.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Golgi SNAP receptor complex member 1-2
- Membrin-11
- Syntaxin-32
- Golgi SNAP receptor complex member 1-1
- Syntaxin-31
- Tlg2p-like protein a
- Vesicle transport v-SNARE 13
- Vesicle transport v-SNARE 12
- Bet1-like SNARE 1-1
- Membrin-12
Sequence:
MKITALLVLKCAPEASDPVILSNASDVSHFGYFQRSSVKEFVVFVGRTVASRTPPSQRQSVQHEEYKVHAYNRNGLCAVGFMDDHYPVRSAFSLLNQVLDEYQKSFGESWRSAKEDSNQPWPYLTEALNKFQDPAEADKLLKIQRELDETKIILHKTIDSVLARGEKLDSLVEKSSDLSMASQMFYKQAKKTNSCCTIL