wanglab/gogpt-training-data huggingface dataset:
Protein: Geranyl diphosphate 2-C-methyltransferase (GPP methyltransferase) (EC 2.1.1.255) (Q9F1Y5)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Function: Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).
Interaction partners:
- 2-methylisoborneol synthase
- Nucleotide-binding protein
- Germacradienol/geosmin synthase
- HNH nuclease domain-containing protein
- Secreted metal-binding protein
Sequence:
MTTETTTATATAKIPAPATPYQEDIARYWNNEARPVNLRLGDVDGLYHHHYGIGPVDRAALGDPEHSEYEKKVIAELHRLESAQAEFLMDHLGQAGPDDTLVDAGCGRGGSMVMAHRRFGSRVEGVTLSAAQADFGNRRARELRIDDHVRSRVCNMLDTPFDKGAVTASWNNESTMYVDLHDLFSEHSRFLKVGGRYVTITGCWNPRYGQPSKWVSQINAHFECNIHSRREYLRAMADNRLVPHTIVDLTPDTLPYWELRATSSLVTGIEKAFIESYRDGSFQYVLIAADRV
Protein: At5g21900 (DNA excision repair protein) (RNI-like superfamily protein) (Q9C597)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DNA repair endonuclease UVH1
- DNA mismatch repair protein MSH3
- N-glycosylase/DNA lyase OGG1
- DNA mismatch repair protein MLH3
- DNA excision repair protein ERCC-1
- General transcription and DNA repair factor IIH helicase subunit XPD
Sequence:
MNSSDFPNDSRENRRINTDGEAIDALFMATEEAVTRDFLSGFQNQDVEMEERKSTEADVVKTGSDYWRDYEVKRNFKAAKHFALELHSDLKIVEKTEEEVEEEVIRDEDKSEFRKAKESIKKRRQEISTTSDMEIDLNVRRKAPSLVELSARVLAQNFLAIKSLKLVPDHLRKKLSYLVSGLGEFDTRLMELLIEDSPSEICAKNCVQLVEDDLVKIFCDCDRVSLKVLILDLCGRSMTDYTINQFFKRAPNGFPSLTTLSLQGAFCLTDNALLLISKSSPLLQYINLTECSLLTYRALRILADKFGSTLRGLSIGGCQGIKKHKGFSSSLYKFEKLNYLSVAGLVSVNDGVVRSFFMFRSSILTDLSLANCNEVTDECMWHIGRYCKKLEALDITDLDKLTDKSLEFITEGCRYLKSLKLTSNRFSDECIAAFLEVSGGSLRELCLNKVRDVGPETAFSLAKVCKMLQFLDLSWCRRLKEDDLRRILRCCSSLQSLKLFGWTQVEDTYLEELSRSDVHITGLKLTSLYAHLDNFYPSVGAKFF
Protein: Serine/threonine-protein kinase Pak (EC 2.7.11.1) (Q9VI13)
Organism: Drosophila melanogaster (Fruit fly)
Function: Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. May be required for the formation of dendritic spines and excitatory synapses (By similarity). During muscle embryogenesis, promotes proper muscle morphogenesis, as well as guidance and targeting of subsets of myotubes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:8628256}. Cell junction, focal adhesion {ECO:0000305|PubMed:8628256}. Cell projection, axon {ECO:0000269|PubMed:10399914}. Cell projection, growth cone {ECO:0000269|PubMed:10399914}.
Interaction partners:
Sequence:
MSSEEDKPPAPPVRLTSNRGGNERSGGGVGVGGGGLGGGGMGDVPPDMRPLPKEPDDSDRKKKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQEQKKNPQAVLDVLKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMPVAPATTPATPLQNHRTPGGISAPAASPMMHNNATTTLDKNKNNANLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEATKGN
Protein: E3 ubiquitin-protein ligase ORTHRUS-LIKE 1 (ORTH-LIKE 1) (EC 2.3.2.27) (Protein VARIANT IN METHYLATION 6) (RING-type E3 ubiquitin transferase ORTHRUS-LIKE 1) (Q681I0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase. May participate in methylation-dependent transcriptional regulation. Mediates ubiquitination with the E2 ubiquitin-conjugating enzyme UBC11.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00358}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- YDG domain-containing protein At5g47160
- YDG domain-containing protein At5g47150
- Small polypeptide DEVIL 23
- F-box/kelch-repeat protein At3g13680
- Putative F-box/FBD/LRR-repeat protein At5g56810
- Putative RING zinc finger protein
- F-box/LRR-repeat protein At3g59210
- E3 ubiquitin-protein ligase ATL41
- F-box protein At5g07610
- Transmembrane protein
Sequence:
MTRVNQLPCDCVSTAEESLTSGTCITPTHVTSLSSPLDRSGDVDPLPVSDESGGSKADESMTDADETKKRKRILSGDCEADENNKSDGEIASLNDGVDAFTAICEDLNCSLCNQLPDRPVTILCGHNFCLKCFDKWIDQGNQICATCRSTIPDKMAANPRVNSSLVSVIRYVKVAKTAGVGTANFFPFTSNQDGPENAFRTKRAKIGEENAARIYVTVPFDHFGPIPAEHDPVRNQGVLVGESWENRVECRQWGVHLPHVSCIAGQEDYGAQSVVISGGYKDDEDHGEWFLYTGRSRGRHFANEDQEFEDLNEALRVSCEMGYPVRVVRSYKDRYSAYAPKEGVRYDGVYRIEKCWRKARFPDSFKVCRYLFVRCDNEPAPWNSDESGDRPRPLPNIPELETASDLFERKESPSWDFDEAEGRWRWMKPPPANHEQRERMKMAMTCLLLFVLIILVGSSSILYQY
Protein: Pre-mRNA polyadenylation factor FIP1 (P45976)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Polymerase-regulating component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase PAP1. This inhibits the extension of an oligo(A) primer by limiting access of the RNA substrate to the C-terminal RNA binding domain of PAP1. Seems to tether PAP1 to the cleavage factor I.
Subcellular location: Nucleus {ECO:0000269|PubMed:12819204}.
Interaction partners:
- Pre-tRNA-processing protein PTA1
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Polyadenylation factor subunit 2
- Poly
- Protein PTI1
- COMPASS component SWD2
- Protein MPE1
- Protein CFT1
- RNA end formation protein 2
- Cleavage factor two protein 2
Sequence:
MSSSEDEDDKFLYGSDSELALPSSKRSRDDEADAGASSNPDIVKRQKFDSPVEETPATARDDRSDEDIYSDSSDDDSDSDLEVIISLGPDPTRLDAKLLDSYSTAATSSSKDVISVATDVSNTITKTSDERLITEGEANQGVTATTVKATESDGNVPKAMTGSIDLDKEGIFDSVGITTIDPEVLKEKPWRQPGANLSDYFNYGFNEFTWMEYLHRQEKLQQDYNPRRILMGLLSLQQQGKLNSANDTDSNLGNIIDNNNNVNNANMSNLNSNMGNSMSGTPNPPAPPMHPSFPPLPMFGSFPPFPMPGMMPPMNQQPNQNQNQNSK
Protein: Tryptophanyl-tRNA synthetase (G3V5U1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQ
Protein: Putative transcriptional regulatory protein C16G5.16 (O60130)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227, ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MSSGDVSRRQRVSRACDECHRRKIKCDQRRPCSNCIAYNYECTYGQPFKRLRHAPEKYIEFLELRLKYLRGLAEESDPNLKLPSFLAPPNDKDSPVNQSPWKRSDSSKRSSSQDEFESLFDRYGQLSLKDDGKADFRGSSSGFVFMKNIHQNIARNSTVPNPVQESNSSSSQPDPLSFPYLPPTPAEDEHKKPPLKIQLPPYEEALSIVSQFFMNDHFLVHIHHPASFFEKMHMYYKTGKTDNNFHFLLVATLCLGYTYMPDESPSANYPYHEAYEYYYYIRSSFSWEDSYTIEVVQILLSVALFALFSSRLSQAYTFTNNALLCCHELGLHKDFSDVLTSHESRLSKRVFYSVYVLACYTSTIVGLPLSIEDVDIDQSLPNSFDFTLENDQVPPRLIASECTSLEVFIQHITLSRILSHFVRKVYPVKSPSDSHCKVSLPAVRDHEEKLTYWWKNLPSYLKMSEVPKFSPKWIQAIILELKFRQIELIFYRPFIHSISTPIDNQNGSPMKPANFALKCAQSAERVVFLLQELAKSPNTPKLFFNLYSGYYALMTLTYCATLTKDDANKSNNFITKARLGFHCLQMIYRESTYYSTIMEAIKNLLIAYDMNSSGTENLDATPDVTGQLPNNFSQRTSNIPREFPQAQIFYSDAPYPGYYNPAQFQNAPTNFPMPTYGGRTQDQSYPRQNGYPSYSDGNVYPHDRVMINYGSSMPTANGFYVPNTYSPVPFPYNTSYPPYMSPTSNMPQAFQAYSQYPYQHPPFPLSEQMLPLPTSGVMMAPGAAKSGMPYPFIQPPSMTNQVAYPTVRDGSNNSPDHPSSSNSKRTE
Protein: Adhesion G protein-coupled receptor G1 (Adhesion G-protein coupled receptor G1 isoform X1) (F1QZM9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKQNPAKTARMWIIICLLFVLGQATDNDRDFKMCGKWLHGIAPQNLEYDLKTGCERIEISANESTLSIQGRITAKCTQSSSIQLDSNPHQNQSHFCVFWEPLLDLLIVEVNGKNHTLCKPNGLQGTCCTDLSQGVQDNAHMYGIVNGSVKGDIITGDLKGNYIFDGAHINCKEKFCDEARLKPRGANMIEEVVMRFNAKGRVDLPCAQGTVIEMDEEFTGHNFTVPAPRFVDANTIPSVYIPSSLRSVSRRKSKVVCTYYKNKTLFERGPSKSALLDDIVGLSVENETIRNLIEPVKIRFHHRPFAPDSSGRCVSWDTKQDNEVNWKDDGCDTVKINEEQTECHCNHLTYFAILVQVEQKSTVRHLKALTFITAVGCAVSLVSCLVLFYWLCKRRRGKKNQISLVHRGLVVAIFLLCLFFILTGILANVANETVCQLTGSLLHYGLLSTLCWMAMEVFHTFLLVRKVFNSPLPIWIFYLMGFGFPFLLVSILLSVGDIYGERKIKPSDDVNNPYRMCWMTEGDKSQLAHYIINIGLLAVVVSSGLVMLFLVVREIRNRPDWKKIHVAFLSIWGLTCLYGTTWALGFLDFGPFSEVTLFLFCIINSLQGFFLMLRYYALERMKKKDVSSSDGSSSGSSKQHMLQTNEKS
Protein: Myomesin 2 (E1BF23)
Organism: Bos taurus (Bovine)
Interaction partners:
- Alpha-actinin-3
- Myozenin 3
- Myozenin-2
Sequence:
MSLVAVPFYQKRHKHFDQSYRNIQTRYLLDEYSAKKKRASAQSSLQRSVTRKSSSQRESSRAALGESTLGETTLGETSLGDTTLGRTTCRLCAKRMSSALEEEAQERKRRYQSMVAAYGEAKRERYLSELAQLEEDVHVARTHARDQLDRLALQHAGRHGLHHAVDDRLAWERHSFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAGEPGKYRIDSKYGVHTLEINRADFDDTATYSAVATNVHGQVSTNAAVVVRRFRGDEEPFHSVGLPIGLPLSSVIPYTHFDVQFIEKFGVTFRREGETLTLKCTLLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLNKDDEGLYTLRIVSRGGITDHSAFLFVRDADPLVTGAPGAPMDVHCHDANRDYVIVTWKPPNATKESPVIGYFIDRCEVGTDNWIQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSEAVAALDPVDLRRLQAVHLEGEKDIVVYQEELEGEVQIPGPPTNVHASETSRTYVVLSWDPPEPRGKEPLMYFIEKSMVGSGSWQRVNAQTAVRSPRYAVFDLAEGKPYVFRVLSANKHGLSDPSEITAPIQAQDTIVVPSAPGRVLASRNTRTSVVVQWDRPKHEEDLLGYYVDCSVAGSNVWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGTSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMILGWKVPKFSGGSPILGYYVDKREAHHKNWHEVNSSPLKERILTVEGLTEGSLYEFKIAAANMAGIGQPSDPSELFKCEAWTMPEPGPAYDLTFCEVRDTSLVLLWKPPVYSGSSPVSGYFVDYKEEDSGEWLTVHETATPHRYLKVCDLHQGKTYVFRVRAVNASGVGRPSDTSEPVLVEARPGTKEVSAGVDEEGNVYLSFDCPEVTDASHFTWCKSYEDIADDDRFKVETAGDHSKLYFKNLDKEDLGTYSVSVSDTDGVSSSFVLDEEELERLKALSNEIKNPTIPLKSELAYEIFDKGQVRFWLQAEHLSPDSSYRFIINDREVADSETHRIKCDKSTGIIEMVMDRFTIDNEGTYTVQIQDGKAKSQSSLVLIGDAFKAVLKEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETEKMPDLEKGVCELLIPKLSKKDHGEYKATLKDDRGQDVSTLEIAGKVYEDMILAMSRVCGASASPLKILCTPEGIRLQCFMKYFTEEMKVNWYHKDAKITSSEHMRIGGNEQMAWLQICEPTEKDKGKYTFEILDGKKNHQRSLDLSGQAFDEAFAEFQQLKAAAFAEKNRGKVIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVVWFKNDKDIELSDHFSVKVEQGKYVSMTIKGVTSEDSGKYSIHVKNKYGGEKIDVTVSVYKHGEEIPDVVLPQQAKPKLLPAAAPSPAH
Protein: Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) (P97863)
Organism: Mus musculus (Mouse)
Function: Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQSGSPSHSDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPNSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSTSPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQPNSSGQVVGKVPGHFTPVLAPSPHPSAVRPVTLTMTDTKPITTSTEGEAASPTATTYTASGTSQANRYVGLSPRDPSFLHQQQLRICDWTMNQNGRHLYPSTSEDTLGITWQSPGTWASLVPFQVSNRTPILPANVQNYGLNIIGEPFLQAETSN
Protein: RELT-like protein 2 (Q8NC24)
Organism: Homo sapiens (Human)
Function: Induces activation of MAPK14/p38 cascade, when overexpressed. Induces apoptosis, when overexpressed.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16389068}; Single-pass membrane protein {ECO:0000269|PubMed:16389068}.
Interaction partners:
- Serine/threonine-protein kinase OSR1
Sequence:
MSEPQPDLEPPQHGLYMLFLLVLVFFLMGLVGFMICHVLKKKGYRCRTSRGSEPDDAQLQPPEDDDMNEDTVERIVRCIIQNEANAEALKEMLGDSEGEGTVQLSSVDATSSLQDGAPSHHHTVHLGSAAPCLHCSRSKRPPLVRQGRSKEGKSRPRTGETTVFSVGRFRVTHIEKRYGLHEHRDGSPTDRSWGSGGGQDPGGGQGSGGGQPKAGMPAMERLPPERPQPQVLASPPVQNGGLRDSSLTPRALEGNPRASAEPTLRAGGRGPSPGLPTQEANGQPSKPDTSDHQVSLPQGAGSM
Protein: Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha) (Q93714)
Organism: Caenorhabditis elegans
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- Probable aconitate hydratase, mitochondrial
- Isocitrate dehydrogenase subunit
- Isocitrate dehydrogenase subunit
- Probable isocitrate dehydrogenase subunit beta, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Isocitrate dehydrogenase
- Isocitrate dehydrogenase
- Cytoplasmic aconitate hydratase
- glutamate synthase
- Probable citrate synthase, mitochondrial
Sequence:
MLGKCIKKASSTVGQSIRYSSGDVRRVTLIPGDGIGPEISASVQKIFEAADAPIAWDPVDVTPVKGRDGVFRIPSRCIELMHANKVGLKGPLETPIGKGHRSLNLAVRKEFSLYANVRPCRSLEGHKTLYDNVDVVTIRENTEGEYSGIEHEIVPGVVQSIKLITETASRNVASFAFEYARQNGRKVVTAVHKANIMRQSDGLFLSICREQAALYPDIKFKEAYLDTVCLNMVQDPSQYDVLVMPNLYGDILSDLCAGLVGGLGVTPSGNIGKGAAVFESVHGTAPDIAGQDKANPTALLLSAVMMLRYMNLPQHAARIEKAVFDAIADGRAKTGDLGGTGTCSSFTADVCARVKDLE
Protein: Cell wall integrity sensor MID2 (Mating pheromone-induced death protein 2) (Protein kinase A interference protein 1) (Serine-rich multicopy suppressor protein 1) (P36027)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cell wall stress sensor. Involved in activation of a response that includes both stress-related increased chitin synthesis and the MPK1 mitogen-activated protein kinase cell integrity pathway. High-copy activator of the SKN7 transcription factor. Required during induction of MPK1 tyrosine phosphorylation under a variety of stress conditions. Required for PKC pathway activation under low pH conditions. Required for cell integrity signaling during pheromone-induced morphogenesis. Activates ROM1 or ROM2 catalyzed guanine nucleotide exchange toward RHO1 in cell wall integrity signaling.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10330137, ECO:0000269|PubMed:10348843, ECO:0000269|PubMed:13679573, ECO:0000269|PubMed:14562095}; Single-pass type I membrane protein {ECO:0000269|PubMed:10330137, ECO:0000269|PubMed:10348843, ECO:0000269|PubMed:13679573, ECO:0000269|PubMed:14562095}. Note=Localizes uniformly around the cell periphery. Also localized to the mother-bud junction.
Interaction partners:
- RHO1 GDP-GTP exchange protein 2
- Protein SLG1
- RHO1 GDP-GTP exchange protein 1
- GTP-binding protein RHO1
- Cell wall integrity and stress response component 2
- Protein MTL1
- Mitogen-activated protein kinase SLT2/MPK1
- Protein kinase C-like 1
- Cell wall integrity and stress response component 3
- Serine/threonine-protein kinase BCK1/SLK1/SSP31
Sequence:
MLSFTTKNSFRLLLLILSCISTIRAQFFVQSSSSNSSAVSTARSSVSRVSSSSSILSSSMVSSSSADSSSLTSSTSSRSLVSHTSSSTSIASISFTSFSFSSDSSTSSSSSASSDSSSSSSFSISSTSATSESSTSSTQTSTSSSSSLSSTPSSSSSPSTITSAPSTSSTPSTTAYNQGSTITSIINGKTILSNHYTTVTYTPSATADSSNKSKSSGLSKKNRNIVIGCVVGIGVPLILVILALIYMFCIQSSRTDFIDSDGKVVTAYRANKFTKWWYMLLGKKVSDEYHSDSPLGGSASSAGGLDLDEADDVMEQSSLFDVRIRDSDSVLPNANTADHNNTNSGGEPINSSVASNDIIEEKFYDEQGNELSPRNY
Protein: THO complex subunit 2 (M9PE28)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MQRSTDRLRRLKKLKSVTGAQDGVGGGDAAATADNRTSASSDTNGAAASSGAGGNQPGTLNPEVFKHLDKSGRSEFLKYLKHQLQDAADTPVYDKNGVFKQGISNAIYQLLWQTLRFTHKKDIVLHLLLEVVALHADFPSLIVDVVNILDSETSLITDGLQEERHAFVQLVKDLDRVIPESLLKERLEIDTLQEAGIVKNKSFYSKFIKVKTKLYYKQRRFNLFREESEGFAKLITELNQEFDENTTPESIMDIIKSLIGCFNLDPNRVLDIIIESFETRPDRWNLFIPLLRSYMPTGAIICEVLGYKFCHFKDSRTPRSLYHVCALLLKHGVIALNDVYVWLTPNDGSIKADWEEDLADAREMVRKLNLIQTNKKEDEKDPPPPPSVKKFNEEKYNANQKFGLCEALLKVGDWENAYKIIQKLPEQAVVLQEPIARAIADLIHLSVENIYYKKCFKAPAGRRPSRNRLYEDSKLVAKMQAKEFGDLRKYTWPMANVLGPAMHYDTVLMYKLIRIMRKLVVDMGVDSLNGPPPNSEAEQHYYDIMSSLDACILPSLLYLDNNCSMSEEIWAVLKYFPYHFRYSLYARWKNDSYQLHPNLIRRCGLAQRDIKALMKRVSKENVKQLGRLVGKYSHCAPGLLFDYILLQIQIYDNLIGPVCDLLKYLTALSFDCLGYCIIESLTLTGRLRFKDDGTSLSLWLQSLASFCGTIYKKYSIELSGLLQYVANQLKSQKSLDLLILREIVHKMAGVESCEEMTNDQLQAMCGGEQLRGEAGYFSQVRNTKKSSNRLKEALANNDLAVAICLLMAQQKHCVIYRETAAHSHLKLVGNLYDQCQDTLVQFGTFLGSTYSVDEYVERLPSIITMLREYHINTDVAFFLARPMFTHQINQKYDQLRKDDPNAKKLTTTQKLQKYLEATQLIMNPIVESVRPLHSSKVWEDISPQFLVTFWSLSMYDLHVPNESYQREVAKLKQLAQQAAEGKDSNQSKNKKEQERYIALMEKLNDERKKQHEHVDKISQRLQEQKDSWFLLRSGKSAKNDTITQFLQLCLFPRCTFTALDALYCAKFVHTIHNLKTSNFSTLLCYDRIFCDITYSVTSCTEGEATRYGRFLCAMLETVMRWHADQAVFNKECANYPGFVTKFRVSNQFSEANDHVGYENYRHVCHKWHYKITKAIVFCLDSKDFMQIRNALIILMRILPHYPVLSKLAQIIERKVDKVREEEKTKRPDLYAIASSYIGQLKLKTPHMLKESVFHQIAERPNKESPTSVGAPAAATRSDKLSPTSPSGNTQGTRAPGGAAPFYNSEQKSVIKEPDAKAASTTRESKSQRGEGNNVTLVSTATSTASNNERESKQRDLPAPRESQSRSKDDQQEQANNGSNGSRQSESRNRDVERDRHDQQDQRSISSHRSSRDIVRVKERTEAELHQRSRERSQRLEELEAQQRKREKTSRRGGEERIRHGDGVETVDLVGSTDNRHYEEFEGRMRDLSSVSNESNGSLHHRQRSHETIEFEKVDSKRRKLESSTSSSKVEELVDSVKKARALKTKERNKDKLSDEERDARKDRKLGRKRDRVDESNSNEHKRRREGQNGEEELRDRERHREKSPRERSHEKFDRERGGASGSRAEERQYISKSARSSRVNY
Protein: Centrosomal protein 192 (A0A286YDK4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
XTIVRASPTPPREQAVEKPRDKIPGQNAEKVSMPWVIQSKSGLANMRETPSLRTGFEDGEPNFTSSQDISSESREPLEAGKMMDSTSGSSEQDLIGQALLDKPALNHRSGPAVPNLPELIQKTVDQGQRLSSTRLSAASSEASSQVPNPGASGTQHNPAPHISAHASVAKVMNQPAVCPALWTGHSLYIAPGAPSGNATLSQCHAGMQVCGISGYSPYPAAAPELVASGLYLGPSLASGLMAPSSLYNLCSTAAPQNLLSTAKPFPMVTNCETEPRDSGMMPAFGNARVPEELRFPHACCVGIASQTLLSVLNPTDHWLQVSIRVLSIWVNGEKVDLSTQTCLVFKNKVVIRPQATEEIKILFIPTSSGIFRCTFSVASWLFSADADTVGQAEALGSRVTLTAIAETPVIEVETEKKGVLDFGDLTYAGWKALPLKLINRTHATVPIRLIINANAVAWRCFTFSKEPIHVSLKAAPHADITAQLAAPSVVSHVMPASYDGKDPEFLVVWVIFHSPKKLLTSEILGSAEEFLARVDIEVDSPNPIPVLRSVALRARAGVARIHAPRDLQTVYLLADVNSSTKHPLPLKNAGNIEVHLDIKVAEQGSQFSVDPESLFLRPGEEHEVTISFTPKDSKACEERILIIFVQPLGPQYEVVLRGEVISSGSKPLPPGPHCSDIPLILSNKQFLTWGGIPLGRTQLQKLALRNSSTTTAQNLRLFIKGQDQDCFQIQNTFGSEERLTSNCEIRICPGEDFVISVLFAPTRLSCMLAKLEIKQLGSRSQPGIKFMIPLSGYGGTSNLILEDVKKLSDSYLITMNDLIPGKESKVVFSIRNTGSRAAFVRAVCFKESQRKVLLDPKVLRIFPDKFVLKERTQEHITLVYTPSSRKNGEKPATELLTVYMFGGDEISRQQYRRAQMHTPGILKQILPEHSVLQHIDFTEAFQDEPLIDEVCDLPQRPNDIELFYGSMRKITLSVIGEFRGTICSREFLQPSSSAESKSNFSSDSKTSGKQSGNVLLDVLPVKGPQGPPFLSQSAHPAQDTAASEEGWAVHPEHLILVAPSSCDLAKTGCFQIINNSVILLKFELYWPAHCLTVTPQHGCIMPEKL
Protein: dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) (Thymidine diphospho-4-keto-rhamnose 3,5-epimerase) (dTDP-4-keto-6-deoxyglucose 3,5-epimerase) (dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase) (dTDP-L-rhamnose synthase) (P26394)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
Interaction partners:
- Glucose-1-phosphate thymidylyltransferase
- dTDP-glucose 4,6-dehydratase
- dTDP-4-dehydrorhamnose reductase
- Glucose-1-phosphate cytidylyltransferase
- dTDP-glucose 4,6-dehydratase
- CDP-glucose 4,6-dehydratase
- Protein RfbI
- Mannose-1-phosphate guanylyltransferase RfbM
- Lipopolysaccharide biosynthesis protein RfbH
- UDP-glucose 6-dehydrogenase
Sequence:
MMIVIKTAIPDVLILEPKVFGDERGFFFESYNQQTFEELIGRKVTFVQDNHSKSKKNVLRGLHFQRGENAQGKLVRCAVGEVFDVAVDIRKESPTFGQWVGVNLSAENKRQLWIPEGFAHGFVTLSEYAEFLYKATNYYSPSSEGSILWNDEAIGIEWPFSQLPELSAKDAAAPLLDQALLTE
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (Q5ZMB9)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MGCIKSKRKANLHGDGLDLKNQPANTDAHLLPGQIFANEETEEHGVIVVALYPYDGLHEDDLSFKKGEKLKVIEELGEWWKARSLTTKKEGFIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNGPGAFLIRESETLKGSYSLSIRDYDPQHGDVIKHYKIRSLDNGGFYISPRITFPSINDMIKHYQKQSDGLCRKLEKACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYHNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGSRLMLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSDLLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINYGSFTIKSDVWSFGILLYEIVTYGKIPYPGMSNSDVMVALQRGYRMPRMETCPAELYDIMKTCWKDKAEERPTFDYLQSVLDDFYTATEGQYQQQP
Protein: Actin (EC 3.6.4.-) (P45521)
Organism: Procambarus clarkii (Red swamp crayfish)
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
Sequence:
VGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWYHTFYNELRIAPEESPTMLTEAPLNPKANREKMTQIMFEAFNLPATYVTIQAVLSLYASGRTTGLVCDSGDGVSHMVPVYEGFALPHAILRLDLAGRDLTNYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFENEMNVSAASSSIDKSYELPDGQVITIGNERFRCPEALFQPSFLGMESVGVHETVHSSIMRCDIDIRKDLFANIVVSGGTTMYPGIADRLQKEITALAPATIKIKIIAPPERKYSVWIGGSILASLSTFQTMWITKEEYDESGPGIVHRKCF
Protein: Peptide-methionine (R)-S-oxide reductase (EC 1.8.4.12) (Q5TZH8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MRCSPRGPPFLYTLLSCSVITLFLLSGTCRSKKTWPKTFPEEELRKRLTPMQYHVTQQKGTESAFTGKYVDNKEEGTYHCVVCGAPLFMSEKKFDSGSGWPSFFDLINKDAIAQTDDFSYGMHRVETTCSQCGAHLGHLFDDGPRPTKKRYCINSASLSFQPKNSATEEVEASGAAGQSSTSKNEEL
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (Q9JKC1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Appetite-regulating hormone
- Amyloid-beta precursor protein
- Amine oxidase [flavin-containing] B
- Amine oxidase [flavin-containing] A
- Beta-secretase 1
- Albumin
- Cochlin
- Serum paraoxonase/arylesterase 1
- Vesicular acetylcholine transporter
Sequence:
MVTEIHFLLWILLLCMLFGKSHTEEDVIITTKTGRVRGLSMPILGGTVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDVYNATKYANSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWIPVPKPKNATVMVWVYGGGFQTGTSSLPVYDGKFLTRVERVIVVSMNYRVGALGFLAFPGNSEAPGNMGLFDQQLALQWIQRNIAAFGGNPKSVTLFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKFIGCSKENEKEIITCLRSKDPQEILLNEKLVLPSDSIRSINFGPTVDGDFLTDMPHTLLQLGKVKTAQILVGVNKDEGTAFLVYGAPGFSKDNDSLITRREFQEGLNMYFPGVSSLGKEAILFYYVDWLGDQTPEVYREAFDDIIGDYNIICPALEFTKKFAELEINAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQGNSTVWPVFTSTEQKYLTLNTEKSKINSKLRAPQCQFWRLFFPKVLEITGDIDEREQEWKAGFHRWSNYMMDWKNQFNDYTSKKETCTDL
Protein: Ribosome biogenesis protein NOP53 (M0QX73)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
Sequence:
XLTKKRTKVQKKSLLLKKPLRVDLILENTSKVPAPKDVLAHQVPNAKKLRRKEQLWEKLAKQGELPREVRRAQARLLNPSATRAKPGPQDTVERPFYDLWASDNPLDRPLVGQDEFFLEQTKKKGVKRPARLHTKPSQAPAVEVAPAGASYNPSFEDHQTLLSAAHEVELQRQKEAEKLERQLALPATEQAATQESTFQELCEGLLEESDAELGADRLAQDPEARGQHPSRPVQELPEEEYDRASRESQVQTQVQGEAGGEAGVP
Protein: Diguanylate cyclase (Q9KXW0)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Interaction partners:
- Circadian input-output histidine kinase CikA
- Circadian input-output histidine kinase CikA
- Regulatory protein
- Membrane associated phophodiesterase
- EAL domain-containing protein
- EAL domain-containing protein
- GGDEF domain-containing protein
- EAL domain-containing protein
- Dimeric protein
- protein-serine/threonine phosphatase
Sequence:
METDSEPYVRLASLRQLHQAMADMNKARSLADTLQAVADGVVQALNYELACVNLVGPDGDLVVAAFAGNPAAEALITGRSGSRESWDRRLGMGEQWGDLIFIPHTEGWVLDDDDVPQWYTDGPAPRFEDEWHPSDRLFAPMYAPGPQGGGNSGELIGVLSVDRPRNGRRPGAWGREALQMYAFQAAIAISNARLRSNMQRALVRLERDQQALRASEESFRQAFEYAPSGMAIAEMGGDQHGRILRTNDALCRLLGRRASSMRRYAFSDLVHPEDIGTLLRTSAEGGRAELRLGRRDGTYVWVSLRNSVVADAADGPRFLLTHVEDIEERKRRELHLAHRASHDSLTGLPNSAELRSRLAARLCQRPQSSHAVADAMDAAYGNSAVFDSGGHTFDFSVAAEPYGAFDHHVHAVAPEDGRDDGAKGLAVLFCDLDGFKSINDRFGHNAGDAVLIEVARRLSGGVRDGDTVARLGGDEFVILANGLGRADAQDLAVRLRGEIIQPIRAEGRAVRVGASFGIGWAHCGMTADEVLKSADERMYVEKRSRPKQHRRAG
Protein: DUF2510 domain-containing protein (O06254)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MVGRAVPSPNRRYRRVWPPRTKGQHLSNPYAQHQLKLIRHTGALILWQQRTYVVSGTREQCEAAYKSAQTYNLLVGWWSLVSLLAMNWIALISNFNAIRRVRAAADGASVPHGPHAIAHPAVPRGPIPAGWYPDPSGAGLRYWDGATWTHWTHPPRHR