wanglab/gogpt-training-data huggingface dataset:
Protein: Male sterile (2) 34Fe (Q9VJT4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Male sterile
- FI06002p
- IP12902p
- Don juan like
- Glutamate transporter polyphemus
- Palmitoyltransferase
- AT28918p
- Uncharacterized protein, isoform A
- AT10852p
- Reticulon-like protein
Sequence:
MSINKSIRGSRRTRRSLASGGGDLIGPYIYCINFYDNGLSAVRDEFVKRLESGLRRAMFVIDLDKEVAEANYQFQRKSRTKKAGSLDMKSLDPLNIVLQCIQNCVEEFDRITKQIESEANFDLYSYWQRNIPAQLKNLLAPKKKGAPDTKRDLNTARSKTGKTSSDKMRLEKIKCSSVTAKEHHKVGKGAPVSKREYIRDNPTFTKMLILIVGQMDNDFYKLLLAYEQPLRAIINFMPEESAYDILVPRPRREQQLQEALAAIQKDIHSLRKRTPTKPVGIFQQRLPQMSACMAAKFTDDIFDQLSWYMYDVETLREWYRSYYVDPYKETNIKMDPSMSLVEAFHIVESLSIQGHYLKTQMPASRNDNGTVYLYLESLMSTFGNPKELMTETEVLLLANPTPSVQTRVLDKVKVYANSFKSIVKMHKNDRIFVEEANGLLSNLISYMDQSLMRNVYHGCLEYNLLRRYFTSGYINSSLKCQPYNGDVEPIYLPKFAELYLTDDSVMQRIIELVKDYDDFSLEEVQPNVHLYTFRRSLNEVFEQENQTVIPTRLCFRDFTLYEMENFLKDLVTPQRFNEVTESYLSRQTESADNIATQDPFIVRCNEENDSVPIDPKVFVRRKSIKEQLAKKKEKERKEQEESRTASRKVSVAQDGLLSSRTFRQSQARATIASILQAKDSTADSKHAFFVGLGRNHPLLEGYNLDDTRQTIKCKTSKYFFEEGRIVLYEERWNFRQMNKCLALEIGGQEVHFRSADNPLGVTAADSSVRIESKNGISLRVLATQTECAKAVLNFPNGLSTYCHDTHTEHVWQYQENVLDESRRVCTPYGCVISFYQSTDTIVIMRYNGEVYQLFTFTEADNEEEEDLNSEFINACSTQSTYSSYQPIRDSKKKQRSCENSLKKTSTTRSVGGLDSIIRPSMFSVDSKKSQSSKKSIGGKRKSQLLKEQQAAALFESIKFELNYLNFIMALYKLSYRHLKLTTSLGSVVHVQRDGKIWCGKPYRNTEWHDYYANESYSMRDDGVKMVWTLGELRCYHNDGTVITSETAEGWDPGTDVDEIDMEISSSSSHANVEIQPSHIFRKETIFINDPEGLPFKDVSISSSQGVVSQRMSLRSKEISSSSDVMPEEEEGEVDLEKSYITFLPNSYFIAHKVYAGIRFTFSHITNVDLHLDTSIFTCDNLKVRVFRAPLTAGVQYSEPVENPSSAADPDEWTKPEVRPSTKSQRSDRSFEETTSSEEQSAEDMDLDVACVEVECSNLALTLFGDRVIIQTHLRKFGCDENAKCDLQVRDDIELKVNFGESLLTTFRNWVDELTSFINCFCPKRRTLYFLETQNRSCQRKGFELHKSVPPLGKYNLCAGNYFIDVNELTSVNSKMQNRHDWYEQDMQKFPRFQTRKKPVKPDFPMVLNSRIYVEIPAQLANTDRIHQFVSEFDSIKYRKQRYRFNEAIMFHLYPRLQLLVQQEISKRSWKNHHEENRRRMFIEQQRFSLYMAMLKHKVYPSYFQFKDQFNSHVRNIEFFQFMTSKCNEKTHPDDIITDPAEEPSPSIKPKFKKNKCVCPKYLKSLD
Protein: Inositol-1,4,5-trisphosphate 5-phosphatase 1 (EC 3.1.3.36) (Synaptojanin-like protein 1) (O43001)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-bisphosphate. Involved in distinct membrane trafficking and signal transduction pathways. Highly active against a range of soluble and lipid inositol phosphates. Active in dephosphorylating the 5-position of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 and to a lesser extent Ins(1,4,5,6)P4. The enzyme is also active against PI(4,5)P2 presented in sonicated vesicles and Triton mixed micelles, and somewhat less active against PI(3,5)P2 in unilamellar vesicles. Activity against PI(3,5)P2 drops sharply when this substrate is presented in mixed micelles. Also hydrolyzes PIP3 to produce PI(3,4)P2.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Note=Localizes at the cell tip and the barrier septum.
Interaction partners:
- Phosphatidylinositol 4-phosphate 5-kinase its3
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1
- Phosphatidylinositol 4-kinase stt4
- Uncharacterized protein C19F5.03
- Uncharacterized protein C3C7.01c
- Phosphatidylinositol 4-kinase lsb6
- Inositol-1,4,5-trisphosphate 5-phosphatase 2
- Phosphatidylinositol 4-kinase pik1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
- Phosphoinositide 3-phosphatase
Sequence:
MQCLLREKPRSLALVNKDHALMFHSVPQNKNSLSVCVAEFTALSEKPLEGFRKISSHRIYGTLGLIELEGSNFLCVISGASEVARVRDKERVFRIMEVCFYSVNRSNWDHIRQENYSPDIPDGYDTDTQGYDSYKYAAEPFSSLRKLLTNGSFYFSLDFDITTRLQLRTSQTMTEPQYDSMHTQFMWNEFMLRQLIKFRSHLNGDEKSALDGCRFFTCAIRGFASTEQFKLGIQTIRLSLISRLSSLRAGTRFLSRGVDDDGNVANFVETETILDSSKYCVSYCQVRGSIPIFWEQEGVQMFGQKIDITRSLEATRAAFEKHFTSLIEEYGPVHIINLLGTGSGERSLSERLRQHIQLSPEKDLIHLTEFDYHSQIRSFEDANKIRPMIYSDAETFGFYFENNEGQSIVVQDGVFRTNCLDCLDRTNVIQNLVSRVFLEQVMIYTRQNAGYDFWQVHSTIWANNGDALARIYTGTGALKSSFTRKGKLSIAGALNDLSKSVGRMYINNFQDKGRQETIDLLLGRLIDQHPVILYDPIHEYVNHELRKRENEFSEHKNVKIFVASYNLNGCSATTKLENWLFPENTPLADIYVVGFQEIVQLTPQQVISADPAKRREWESCVKRLLNGKCTSGPGYVQLRSGQLVGTALMIFCKESCLPSIKNVEGTVKKTGLGGVSGNKGAVAIRFDYEDTGLCFITSHLAAGYTNYDERDHDYRTIASGLRFRRGRSIFNHDYVVWFGDFNYRISLTYEEVVPCIAQGKLSYLFEYDQLNKQMLTGKVFPFFSELPITFPPTYKFDIGTDIYDTSDKHRVPAWTDRILYRGELVPHSYQSVPLYYSDHRPIYATYEANIVKVDREKKKILFEELYNQRKQEVRDASQTSYTLIDIAGSVAGKPNLIPHLPANGVDKIKQPSSERSKWWFDDGLPAKSIAAPPGPEYRLNPSRPINPFEPTAEPDWISNTKQSFDKKSSLIDSIPALSPAPSSLARSSVSSQRSSTSIIPIKPNKPTKPDHLVAPRVKPLLPPRSGSSSSGVPAPNLTPVNVPPTPPPRKSSASQRSGDLLASSPEESSISWKPLV
Protein: Dipeptidase (EC 3.4.13.19) (A0A140VJI3)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004303}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004303}. Membrane {ECO:0000256|RuleBase:RU341113}; Lipid-anchor, GPI-anchor {ECO:0000256|RuleBase:RU341113}.
Interaction partners:
Sequence:
MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSSGASSLHRHWGLLLASLAPLVLCLSLL
Protein: Photosystem I reaction center subunit VIII (PSI-I) (Q6ENG4)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: May help in the organization of the PsaL subunit.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00431}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00431}.
Interaction partners:
- Photosystem I reaction center subunit IX
- Photosystem I reaction center subunit psaK, chloroplastic
- Chlorophyll a-b binding protein
- Photosystem I iron-sulfur center
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I reaction center subunit XI, chloroplastic
- Photosystem I reaction center subunit VI
- Uncharacterized protein
- Photosystem I P700 chlorophyll a apoprotein A1
- Chlorophyll a-b binding protein
Sequence:
MMDFNLPSIFVPLVGLVFPAIAMASLFLYVQKNKIV
Protein: Protein Vpx (Viral protein X) (X ORF protein) (P18045)
Organism: Human immunodeficiency virus type 2 subtype A (isolate Ghana-1) (HIV-2)
Function: Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity).
Subcellular location: Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG. {ECO:0000250}.
Interaction partners:
Sequence:
MTDPRERVPPGNSGEETIGEAFEWLDRTIEALNREAVNHLPRELIFQVWQRSWRYWHDDQGMSPSYTKYRYLCLMQKAVFIHFKRGCTCLGGGHGPGGWRSGPPPPPPPGLV
Protein: Uncharacterized protein (Q386T2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- ODAD1 central coiled coil region domain-containing protein
- Dynein heavy chain, putative
- Dynein heavy chain
Sequence:
MSTEAEDDQLLAEAVATNKTSDTELASPLGVASSGDGINTLFRFSHATSEKVATGCATDWMSDRLLAVAQGLKTIVPKGTWESLGSEEEVIEENGYNVKKRPQVRVAFEVRRDILLHQRLGNANYLTKEASEDSRDQRGTVNALYEIMRDEVDASVQAVAPVMDRPSQTPFSRKVDATVQAEPTLVDMCIRGTPLPPVDMSAMRGFFSKVLPRTLHCLLQNYEIPIYQDDFAMFSEDYAIVGSRDDIVLIERGNYTHTTMKDLRVSSISWRSSRSKDDVVCIASVARHNLEQRIEAEKLCETVTNLVWDFADPMHPYALLEAPVEIQVVRFNPLRTNLIAGGAMNGQLFLWDLDKISGSAAGTRSPKDRTLDPTAAARAEHGPKDIPPMPMNVKGVTMRRDGDVLVPHLQPCQASRMELSHRRAVHDIQWLPNGLECAFGGKQTVTQEGRQFVSLSDDGYMCVWDIRPEYLPADKLRKMKHQGRIGGEDFPWVPLLRFQMSKPGGGGDVAGFRFHVDGLQASETPSYRACCGSLHGEIAVCSMLVPDERRDFSAGSEDVRVVQQLLRGHAGPVYSIQRHPTISDVYLTCGDVQFKIWRVGTEFPILTSPQHDTAITCARWSPTRVSVLVVGTADGKILVWDLLDRNSEPLLVHQLVQDAITVINFKPAPASVPATYVQYVAIGTSVGSFHWYALPKVLSRGPSGEQRHFRAVLEREVRRVLFFQWRWSERNRERDRYGHAAPKMRDRDHETPAAITADSNWGNEDNYYAYDHHRDAEFLAKVEAFRPEEDTMSLSELDGDGADTRASPI
Protein: E3 ubiquitin-protein ligase (EC 2.3.2.27) (A0A1D8PLP8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- HECT-type E3 ubiquitin transferase
- Ubiquitin-conjugating enzyme E2 2
- Cup9p
- Polyubiquitin
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MNPDLLKVFLIEVPKNLGFDDFKGLQHYITKVLFYSATDEGKYLKTLFPRISPEDFDPSTVYNIPSSTEVLNPFYEVSGSKYSHPPDEACAKPFQPGDPVYRCDECGFDSTCVLCASCFNKEDHLNHNVTVYTSSGTSGGICDCGDPEAFIRPLNCKCQTNRDELEEDVSGMMDALQKTIQIAIDYVLDVSNFTIMTLPLIHTELNEQYPKLDIRELSDYLSLPEESYSGASDVNSTNRWALILWNDEFHNLTEAVTAIKAGTGVDDRNAYKIAEKIDIKGFCVLKEDDNPQKLIQAKRLVESNGLVATIVSARDLLREKIASSIIDWIIAISNSSNSQVRKAAQSYFAELLLEPHFRFSKVIPSSVFQETLASKSTQDQFLAYFKNGLPYNGELISFNYHQLRATANQISLYEPISSLLDSTRSTERLKGSRLQYLLAFQIRFPKLTRQKLGTLLVPPLVTTSTLKREFANQFVELFPALLTIMGLTDREEDLNLMSDITSQLFTCPQTVRSILDKGGVKNLLGPLAKLIEEHSTTRDTNTGYRLYCEIGSDSQQKRAIKKAIVHGIYNLSYFSNHGLSGDSITKFLQPDHFSLLVLMLRYFQSYWPVTRKYGEHVERDDFDLSVHVEISLPILKCVKNLGVDMPRNKEIPTVVAQLIELLSKKKNEFIEPGVIKFQVSKEPVAIVNPLNSLLSYFLQFQNIDNFKHLLQQNQSELVNFTDISLRSIVLGSQVKAGFWIRNGSSVSRQATAYFDSLMTEYAFMRDFHLNQIAILFEDQEKVLMNFLERWELRSWFKNEVDFDKTIYEERFFSIVERFIAFAYNLFVDRSMFINETPEDATLRKLNHAIGYALCEEAMAFSELHQYIDTNIASSSKFEDVLYEVADYQPPSALTDSGLYRLKESTYEKLDPLNILVDPGKFQIISEMVIKNSSKQKKRKSENLIVTPVIEKAGNDFVDENIGNFAKSLPFVKLIYKLMQVSIDTSDETYLPHLLHLVHAIMLDDEMIHGKEYLNKHFVDIPITDLLLTISESTMSKYVCQKADYLVEQLVGKDKRIIASLVDCFGEDYIQRYKKRKNSLFESDAERKKRKAEKRKNNIFKKFSKQREKFLNQNQEFQSDIPQDSNIPMEGEDSRKLRTCVACGELESFEKPLAIMAASTKAPVFWKVPVQTGEVVSNAFKTWDKNILLDYKDTEYGVGYDPVSRSSLDSNRFESYVLSTCGHSIHHSCLNRRIIGSAQYSCPLCHNLHDMIILTLLGNRDSNIPAEVFNGSPNHLKYNQIVESADPNRKLGYLLDVFFKPEYFDAPSKTVTMASLGEAPLNHFKNQKYLPPGINSSYGIIFNRLMNWTVVLADTIRMNEISTRLNGVDGYSDFLSQIPGSAKTLLICMFQMRVLNAASSLLPLSADESNTFQSEFKSFWNSDLILDGVFNEVLVLFFQTDESLATLTRVGMSKLIAIVIKSLTARHEKDNSYLKCIDVDNGNQVSDVSLERFHRLFTGVMHGNDCEIPEVDKSISLIIYCAIERILGIFLRQVIIFKDILTCKQTGENNYESIPELLDLQKKIKLQDRLTDTKPLTDALGVPSFDELIETLLESSDALEGNVFDIIWLAKIPKYHDKGILTLEYPGIVHLVNLPVDYNSCVLNASQIATHDNSKCLICGQWTNASRNVAHMLNCSSQIGILFISKSNMLRICVYIGTSPITIELPAPYLTKHGEIKVIDKRGRATLSGLRFAYLNKLWVTQGLYGFVTRNLFGSGFALEDDVTFNFERNIPDLSEDDDGIGLFEWVD
Protein: Adaptor related protein complex 1 subunit sigma 3 (F8W8K9)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
Sequence:
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRCL
Protein: Probable WRKY transcription factor 12 (WRKY DNA-binding protein 12) (Q93WY4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- NAC domain-containing protein 66
- Transcription factor MYB46
- NAC domain-containing protein 30
- NAC domain-containing protein 43
- NAC domain-containing protein 73
- Transcription factor bHLH48
- NAC domain-containing protein 12
- Transcription factor E2FC
- Myb domain protein 42
Sequence:
MEGGGRRVFSNYDLQQVTSSSTTIQENMNFLVPFEETNVLTFFSSSSSSSLSSPSFPIHNSSSTTTTHAPLGFSNNLQGGGPLGSKVVNDDQENFGGGTNNDAHSNSWWRSNSGSGDMKNKVKIRRKLREPRFCFQTKSDVDVLDDGYKWRKYGQKVVKNSLHPRSYYRCTHNNCRVKKRVERLSEDCRMVITTYEGRHNHIPSDDSTSPDHDCLSSF
Protein: Protein DEFECTIVE IN MERISTEM SILENCING 3 (Protein INVOLVED IN DE NOVO 1) (Q94A79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the RNA-directed DNA methylation (RdDM) machinery, probably by facilitating an RNAi-mediated epigenetic modification involving secondary siRNAs and spreading of DNA methylation, thus leading to gene silencing. Involved in the assembly of RNA polymerase V (Pol V) transcription initiation or elongation complexes at the chromatin, as a component of the DDR complex. Required for de novo DNA methylation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein CHROMATIN REMODELING 35
- Protein RDM1
- DNA-directed RNA polymerase V subunit 1
- Protein MICRORCHIDIA 6
- DNA-directed RNA polymerases IV and V subunit 2
- Protein argonaute 6
- DNA
- Protein INVOLVED IN DE NOVO 2
- Histone-lysine N-methyltransferase family member SUVH9
- Protein SAWADEE HOMEODOMAIN HOMOLOG 1
Sequence:
MYPTGQQISFQTTPLNVQDPTRMMNLDQSSPVARNETQNGGGIAHAEFAMFNSKRLESDLEAMGNKIKQHEDNLKFLKSQKNKMDEAIVDLQVHMSKLNSSPTPRSENSDNSLQGEDINAQILRHENSAAGVLSLVETLHGAQASQLMLTKGVVGVVAKLGKVNDENLSQILSNYLGTRSMLAVVCRNYESVTALEAYDNHGNIDINAGLHCLGSSIGREIGDSFDAICLENLRPYVGQHIADDLQRRLDLLKPKLPNGECPPGFLGFAVNMIQIDPAYLLCVTSYGYGLRETLFYNLFSRLQVYKTRADMISALPCISDGAVSLDGGIIRKTGIFNLGNRDEVNVRFAKPTASRTMDNYSEAEKKMKELKWKKEKTLEDIKREQVLREHAVFNFGKKKEEFVRCLAQSSCTNQPMNTPR
Protein: Calnexin 99A, isoform E (Q0KHZ9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004389}.
Interaction partners:
Sequence:
MAWKMGGNRAATLALLFASSLLLLSAANAADLDTESDDFEDGYVEDVQEEPAVIGGDEKLAYESPVIDAKKFHFADHFDDVEESRKRWVLSQAKKDDIAEEISKYDGIWNWESPQRIVWANDLGLVLKSKAKHAAIAAPLRKPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFNDKTPYTIMFGPDKCGNDVKMHFIFRHVNPINGTITEKHCNKPKNRLEEPFKDKLPHLYQLVVRPDNSFEIRVDHKIINEGSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPPQLPDTDAVMPNGWLEDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIPNPNYKGKWRAPMIENPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAANSFDIKRRYIDRESKTFWHRLMRRMNYKPGWWALYFVYLLIPASCYVFYLYRRAKEDSAAKKAAAEAKKSDDPQPDDEPEAEEESDERAAGDTSKESTPLSASPKKNQKSDLDDNEEESKAAESREPAQTEESNTKTRKRQARKE
Protein: Uncharacterized transporter C11D3.06 (Q10085)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Putative agmatinase 1
- Uncharacterized membrane protein C3H7.05c
- Uncharacterized protein UNK4,15
- Uncharacterized transcriptional regulatory protein C139.03
- Putative agmatinase 3
- Uncharacterized transcriptional regulatory protein PB24D3.01
- Putative uracil phosphoribosyltransferase urg2
- Uncharacterized transcriptional regulatory protein C1399.05c
- Aromatic amino acid aminotransferase C1773.13
- Uracil phosphoribosyltransferase 2
Sequence:
MGRPLTEVKYLLINSAPVILGYALQNSLQTSSVIVTGRLGPSELSVAAFAYMFAMSTGWLIALGGTTAFDTLGSNLWGAGKKQELGILLQTGFIVLSILYLPICLVWWYSKPILIFLHQTPELAEASQKFLRYLIPGGLGYVCFELLKKFLQTQEITRAGSYILLVTSPLNVALNFLLVHYYGLGLKGAPLATGLSYWLSFILLTQYAKYVKGAEAWNGWNKRCLENFGPFVKLSLLGIVMVGTEWWAFEIVALVAGKLGAVPLAAQSVIMTTDQLLNTIPFGLGIITSNRVAYYLGAGLPDNASLTAKVAAIVGVAVGSVIMITMIAVRNIYGRIFTNDPDVIQLVALVMPLVAAFQISDSLNGTMGGALRGTGRQKVGAIVNITAYYLFALPLGIYLAFHGKGLVGLWIGQVIALSIVGILELKIVMATDWISQSRKAISRFGDSSELTALLN
Protein: Calcium-dependent protein kinase 33 (EC 2.7.11.1) (Q9C6P3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ca(2+)-dependent protein kinase. Negative regulator of stomatal closure and slow anion currents. Unable to phosphorylate THI1 in vitro, but the kinase activity is essential for the stomatal closure regulation. Phosphorylates FD. May play a role in signal transduction pathways that involve calcium as a second messenger (Probable).
Subcellular location: Cell membrane {ECO:0000269|PubMed:26662273}; Lipid-anchor {ECO:0000305}. Nucleus {ECO:0000269|PubMed:25661797}. Cytoplasm {ECO:0000269|PubMed:25661797}.
Interaction partners:
- Thiamine thiazole synthase, chloroplastic
- Potassium channel GORK channel)
- Respiratory burst oxidase homolog protein F
Sequence:
MGNCLAKKYGLVMKPQQNGERSVEIENRRRSTHQDPSKISTGTNQPPPWRNPAKHSGAAAILEKPYEDVKLFYTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGRVYKDIVGSAYYVAPEVLKRRYGKEIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVLKHPWLREGGEASDKPIDSAVLSRMKQFRAMNKLKKLALKVIAENIDTEEIQGLKAMFANIDTDNSGTITYEELKEGLAKLGSRLTEAEVKQLMDAADVDGNGSIDYIEFITATMHRHRLESNENVYKAFQHFDKDGSGYITTDELEAALKEYGMGDDATIKEILSDVDADNDGRINYDEFCAMMRSGNPQQPRLF
Protein: V-type proton ATPase subunit a (Q9JHF5)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- V-type proton ATPase subunit d 2
- V-type proton ATPase 16 kDa proteolipid subunit c
- V-type proton ATPase 21 kDa proteolipid subunit c''
- V-type proton ATPase subunit d 1
- V-type proton ATPase subunit H
- V-type proton ATPase subunit S1
- V-type proton ATPase subunit E 1
- V-type proton ATPase subunit D
- V-type proton ATPase subunit B, kidney isoform
- V-type proton ATPase 116 kDa subunit a 1
Sequence:
MGSMFRSEEVALVQLLLPTGSAYNCVSQLGELGLVEFRDLNESVSAFQRRFVVDVRRCEELEKTFTFLREEVQRAGLTLAPPEGTLPAPPPRDLLRIQEETDRLAQELRDVRGNQQALRAQLHQLRLHSAVLGQSHSPPVAADHTEGPFSETTPLLPGTRGPHSDLKVNFVAGAVEPYKAAALERLLWRACRGFLIASFRETEGQLEDPVTGEPATWMTFVISYWGEQIGQKIRKITDCFHCHVFPYLEQEEARFRTLQQLQQQSQELQEVLGETDRFLSQVLGRVQQLLPPWQVQIHKMKAVYLTLNQCSVNTTHKCLIAEVWCAARDLPTVQQALQSGSSEEGVSAVAHRIPCQDMPPTLIRTNRFTSSFQGIVDAYGVGRYREVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAMVLTENRPAVKAAQNEIWQTFFGGRYLLLLMGLFSVYTGFIYNECFSRATTIFPSGWSVAAMANQSGWSDEYLSQHSMLTLNPNITGVFLGPYPFGIDPIWSLATNHLSFLNSFKMKMSVILGVTHMAFGVFLSIFNHVHFGQAHRLLLETLPELIFLLGLFGYLVFLIVYKWVNVSAASASSAPSILIHFINMFLFSQNPTNHLLFHGQEVVQYVLVVLALATVPILLLGTPLYLLRQHRHRRNTQRRPAGQQDEDTDKLLASPDASTLENSWSPDEEKAGSPGDEETEFVPSEIFMHQAIHTIEFCLGCISNTASYLRLWALSLAHAQLSEVLWAMVMRIGLGMGREIGVAAVVLVPVFAAFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFTFTVDSD
Protein: Beta-crystallin A2 (Beta-A2 crystallin) (P53672)
Organism: Homo sapiens (Human)
Function: Crystallins are the dominant structural components of the vertebrate eye lens.
Interaction partners:
- Alpha-crystallin A2
- Alpha-crystallin B chain
- Filensin
Sequence:
MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIRRVQH
Protein: 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN (P37675)
Organism: Escherichia coli (strain K12)
Function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system YiaMNO involved in the uptake of 2,3-diketo-L-gulonate.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- 2,3-diketo-L-gulonate-binding periplasmic protein YiaO
- 2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM
- Putative L-ribulose-5-phosphate 3-epimerase SgbU
- 3-keto-L-gulonate-6-phosphate decarboxylase SgbH
- L-xylulose/3-keto-L-gulonate kinase
- L-ribulose-5-phosphate 4-epimerase SgbE
- Protein YiaL
- 2,3-diketo-L-gulonate reductase
- Uncharacterized HTH-type transcriptional regulator YeiE
Sequence:
MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAMIMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFGVSSGLSISKLFMAGIAPGMMMGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIWALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTSVVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTPTVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDAVRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN
Protein: Longin domain-containing protein (Q388Z8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004394}.
Interaction partners:
- Syntaxin 5
- SNARE protein, putative
- Golgi vesicular membrane trafficking protein, putative
- t-SNARE coiled-coil homology domain-containing protein
- Vesicle-associated membrane protein, putative
- Golgi SNARE protein-like
- Vesicle transport v-SNARE N-terminal domain-containing protein
- Sec1 family transport protein, putative
- Synaptobrevin-type vesicle transport protein, putative
- Protein kinase
Sequence:
MLYFTLIVRQQNALVLAADTDTCSEEIEQCKATAKGLLRKLTLDGKKLSVDMPPLLTVSWKNYLFYILAESGVLFLTMCDVATPASIPQAYLEDVAREFLLQYGSQVEAATRPYCFIKFDLYLLRTKKVFTAPSSSRLNIARSGRPMPVKRSYQEIMSGIQNKPTPSSLPSSAADDGNYFFWVATLCLLAVAILIILVYVFYLSA
Protein: Early nodulin-like protein 19 (AtENODL19) (Phytocyanin-like protein ENODL19) (Q9STZ8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- SKU5-similar 6
- Early nodulin-like protein 8
- Uncharacterized GPI-anchored protein At3g06035
- RING-type E3 ubiquitin transferase
- AT3g13990/MDC16_11)
- Embryo-specific protein 3
- Serine carboxypeptidase-like 43
- F3F9.4
- EP1-like glycoprotein 1
Sequence:
MGRSMVLISAVVLAFLVAAPIPEVTAKKYLVGDKKFWNPNINYTLWAQGKHFYVGDWLYFVFYRDQHNILEVNKADYEKCISNRPIRNYTRGAGRDIVPLYETRRYYLLDGRGGCVQGMKLDVLVETPPPPPPFTPPPPAQ
Protein: Magnesium-dependent glutamate N-prenyltransferase (EC 2.5.1.-) (Domoic acid biosynthesis cluster protein A) (PmDabA) (A0A386KZ50)
Organism: Pseudo-nitzschia multiseries (Marine planktonic diatom) (Nitzschia pungens f. multiseries)
Function: Magnesium-dependent glutamate N-prenyltransferase: part of the gene cluster that mediates the biosynthesis of domoic acid (DA) and derivatives, natural products with neurochemical activity acting as ionotropic glutamate receptor (iGluR) agonists, thus being neurotoxins causing amnesic shellfish poisoning (ASP). Catalyzes the conversion of L-glutamic acid (L-Glu) to N-geranyl-L-glutamic acid (NGG) in the presence of geranyl diphosphate (GPP). Also able to catalyze the formation of farnesyl-L-glutamate from farnesyl diphosphate (FPP). Cannot use dimethylallyl diphosphate (DMAPP) as substrate.
Interaction partners:
Sequence:
MKFATSIVAAIATTGAAFTVIPQKLSHPSQLNALNTMGSISSITAESPKEVLSRVQDAGLTLTNPNDLYWMVDFLKEKYYDNGDYYYPIKTVCDGESIDVKFYCPFEPSLSPHYLELYGSRDERASIYETTMKKYNRINSEKTSAICTPYSSYGDTQIVAYFYSMMYYINDQTAHLKLPESEIESELIDILNDDILIYLNEFMSIFEPEDAQDLERIWDFLDFYQPYFSKVDGKIVLDEKYLVRTPSQMPLIKTICEYVSEQFAPSKNITQVIWEVVRYIKGVKDEIHIRGDKSFTLSLQEYDDFRDKVTASPMAHAVSDLTHERFSYEAYTNPAFMELENRCSEIITYFNDVCTSDRERLDEDPFNSVFILMDLDPSLNFAKSCDVVVEHAYNKMQAFLKLKEEILESASDEEERLALARMIKTREDSLIGYVLHEVCCVEDGYARDHKPLMKAFLEEEITKSLAEKVKFNPVESESVRLN
Protein: Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5) (Q9H3K2)
Organism: Homo sapiens (Human)
Function: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:18417609}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Toll-like receptor 4
- Lymphocyte antigen 96
- COP9 signalosome complex subunit 7a
- Schwannomin interacting protein 1
- Ubiquitin carboxyl-terminal hydrolase MINDY-3
- Transmembrane protein 45A
- Phosducin-like protein
- Proton-transporting V-type ATPase complex assembly regulator TMEM9
Sequence:
MLAARLVCLRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYATKTRIGIRRGRTGQELKEAALEPSMEKIFKIDQMGRWFVAGGAAVGLGALCYYGLGLSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLTALSAIAISRTPVLMNFMMRGSWVTIGVTFAAMVGAGMLVRSIPYDQSPGPKHLAWLLHSGVMGAVVAPLTILGGPLLIRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSSLGSMFLPPTTVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYMDTLNIFMRVATMLATGGNRKK