wanglab/gogpt-training-data huggingface dataset:
Protein: Crossveinless 2 (Q9GYX3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MCCQSSGQWKFPAQQPRKSSAPRRRHTGFRPSTQLLILIAVLLALLQGRTVDAGAGDSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNGFVNCRDTCPPVNDCYILDKSNGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRCPQNHSFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAPEFQEPDGCCPRCAVAEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGKTFHIRLTNEGRGTRRSSWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLADGGAVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTRDKRKSNFYCHPLSVPALFGECNERLNPENYKAACRMDVCECPSGDCHCDSFAAYAHECRRLGVQLPDWRSATNCPAGWRRNATLSSFKGNQFYGDPSFSRMKGRRQKNHQLRLQLQQEQQQRSKQGQKGRHKPGGHNQLDRQGHNGLDKDQLQKEFILKHVPSSFLYPRAPDRTPPPLH
Protein: Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327) (O43699)
Organism: Homo sapiens (Human)
Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Subcellular location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Interaction partners:
- Leptin
Sequence:
MQGAQEASASEMLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYGYGYWFLEGADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPEGRAGGVLGAVWGASITTLVFLCVCFIFRVKTRRKKAAQPVQNTDDVNPVMVSGSRGHQHQFQTGIVSDHPAEAGPISEDEQELHYAVLHFHKVQPQEPKVTDTEYSEIKIHK
Protein: Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (DRAP deaminase) (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)] (P25539)
Organism: Escherichia coli (strain K12)
Function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
Interaction partners:
- Riboflavin synthase
- GTP cyclohydrolase-2
- 6,7-dimethyl-8-ribityllumazine synthase
- 3,4-dihydroxy-2-butanone 4-phosphate synthase
- Thiamine-monophosphate kinase
- Transcriptional repressor NrdR
- 5-amino-6-
- Transcription antitermination protein NusB
- Bifunctional riboflavin kinase/FMN adenylyltransferase
- 5-amino-6-
Sequence:
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGRTAMASGESQWITSPQARRDVQLLRAQSHAILTSSATVLADDPALTVRWSELDEQTQALYPQQNLRQPIRIVIDSQNRVTPVHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLCTLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA
Protein: RELA proto-oncogene, NF-kB subunit (A0A8I5ZMV7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MRLVLASFPYLFPLIFPSEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNGPTEPRPPPRRIAVPSRGPTSVPKPAPQPYAFSTSLSTINFDEFSPMVLPPGQISNQALALAPSSAPVLAQTMVPSSAMVPSLAQPPAPVPVLAPGPPQSLSAPVPKSTQAGEGTLSEALLHLQFDADEDLGALLGNNTDPGVFTDLASVDNSEFQQLLNQGVAMSHSTAEPMLMEYPEAITRLVTGSQRPPDPAPATLGTSGLPNGLSGDEDFSSIADMDFSALLSQISS
Protein: Homeobox domain-containing protein (H9G2W7)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MACREEIAVWISLTEPRVRVWFKNRRAKWRKRERNYVIDNGQGTTKVTAQSLDPLGSLQNTFPQTLLQSSSSQLDDSAVTSSSFYGYGGAWQQNPYYSRNNQTTFNWQIKPQFQTIPMSPTTATSRFSTAANLAPLPTAQAAFSTSATSSNDKLKLMDGLSNSLSSSLGQPYQPCQYSGPL
Protein: Meprin A subunit beta (EC 3.4.24.63) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta) (Q16820)
Organism: Homo sapiens (Human)
Function: Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22988105, ECO:0000269|PubMed:27180357, ECO:0000269|PubMed:34125978}; Single-pass type I membrane protein. Secreted {ECO:0000269|PubMed:10215852}. Note=Homodimers are essentially membrane bound but may also be shed from the surface by ADAM-10 and ADAM-17. {ECO:0000269|PubMed:22988105}.
Interaction partners:
- Angiotensin-converting enzyme 2
- Xaa-Pro aminopeptidase 2
- Lysosomal Pro-X carboxypeptidase
- Meprin A subunit alpha
- Neprilysin
- Dipeptidyl peptidase 4
- Receptor-type tyrosine-protein phosphatase U
Sequence:
MDLWNLSWFLFLDALLVISGLATPENFDVDGGMDQDIFDINEGLGLDLFEGDIRLDRAQIRNSIIGEKYRWPHTIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRIATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKTAFQNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCGMIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAVLESRTLYPKRGFQCLQFYLYNSGSESDQLNIYIREYSADNVDGNLTLVEEIKEIPTGSWQLYHVTLKVTKKFRVVFEGRKGSGASLGGLSIDDINLSETRCPHHIWHIRNFTQFIGSPNGTLYSPPFYSSKGYAFQIYLNLAHVTNAGIYFHLISGANDDQLQWPCPWQQATMTLLDQNPDIRQRMSNQRSITTDPFMTTDNGNYFWDRPSKVGTVALFSNGTQFRRGGGYGTSAFITHERLKSRDFIKGDDVYILLTVEDISHLNSTQIQLTPAPSVQDLCSKTTCKNDGVCTVRDGKAECRCQSGEDWWYMGERCEKRGSTRDTIVIAVSSTVAVFALMLIITLVSVYCTRKKYRERMSSNRPNLTPQNQHAF
Protein: AT3G13000 protein (Q56W79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MYDSQVLKSKYNPFLRRSHSGKKFQGTVTMSEGRETCEESTSGESFPYRFQLEEDVKRLQLQLQQEIDLHTFLESVMEKDPWELSYSSSVPHPAQELLSNIVTLETAVTKLEQEMMSLNFQLSQERNERRLAEYQLTHSASPLNSSSSLRYLNQSDSELHQSAEDSPSQDQIVHYQESSSESSPAESTVEQTLDPSNDFLEKRLMRKTNARKLPRGMPPKYLWDQPNLLSEEMVRCMKNIFMSLADPTATSKASSNESHLSPVSPRGHLSSSASWWPSTERSMISSWVQSPQIDIQNNANVLATGDVFDPYRVRGKLSWAEIGNYSLASEVSWMSVGKKQLEYASGALKKFRTLVEQLARVNPIHLSCNEKLAFWINLYNALIMHAYLAYGVPKSDLKLFSLMQKAAYTVGGHSYTAATMEYVILKMKPPMHRPQIALLLAIHKMKVSEEQRRASIDTHEPLLGFALSCGMYSSPAVRIYSAKGVKEEMLEAQRDFIQASVGLSSKGKLLLPKMLHCYAKSLVEDSNLGVWISRYLPPHQAAFVEQCISQRRQSLLASRNCGILPFDSRFRYLFLPDDNTSL
Protein: Desmethylyatein synthase (EC 1.14.14.131) (Cytochrome P450 family 71 subfamily CU polypeptide 1) (A0A0N9HTU1)
Organism: Sinopodophyllum hexandrum (Himalayan may apple) (Podophyllum hexandrum)
Function: Cytochrome P450 involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family. Catalyzes the conversion of bursehernin to demethylyatein.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
METFQCLTLFLLFISTVFILKRKFSHKPNLPPSPPKLPILGNFHQLGTLVHRAVTVLAAKYGPLMLLHFGKTPVLIVSSQETAKEIMKTHDLALANRPLTTAARALLYDCTDISFAPYGEYWREMKKMAVLNLLSIKKIQSFRSVREELASDMIKEITRLSKTGAPVDVTNMLYHFSEDLLFRCTLGFKPKGQHKFQKLSRDFLDLVGAFCFNDFFPGMAWMDALTGLNRKLKKGSRELDDFVDELIEERIAMVKDGVEPNEFLDLLLHTHRDTTQEIKLTRDNVKAIILDTFLGGIDLPASVMEWAMAELMRNPSKMKIAQEEVRKVVGNKNKVDEDDVYQMNFLKSAVKETLRLHPPAPLLFARESYTSINVENYIIPPYTSVMINIWHIQRDPKLWDKAEEFIPERFMNSGIDYKSHDYEFIPFGSGRRGCPGMSFGVAAVEFAVANLLYWFDWKFVGDTTPETLDMTEDYCFALFKKKPLHFIPISRSS
Protein: Cholinergic receptor nicotinic alpha 1 subunit (Cholinergic receptor, nicotinic, alpha 1 (Muscle), isoform CRA_c) (G5E9G9)
Organism: Homo sapiens (Human)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGGCGCHDCCC
Protein: COP9 signalosome complex subunit 1 (Signalosome subunit 1) (Q54QX3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 2
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 8
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 7
- DNA damage-binding protein 1
- Cullin-4
- Elongin-C
Sequence:
MEDMQVEKNTEGSSSSSSNNNNNNSISNEFDLETYINNYSGFTKIHRLIFIADNCKQLEVEAYNMALKEVQKTPNLELYNTIINKSHGILELDPVYIENLSKKNSLQLDKLEQDLNTAKSNMVKDSIRFAQNDLGEFYYKIGDHQNALKCFIRTRDYCTTSKHVLAMCFNIIKLGVDTQNYTHAPSYIAKAEQSPDLDNVSNAKLRSVNGLYNLDGSRYKLAARKFIETPFEQSNVFSDIISPQDIAYYGGLCALATFDRNELKKKVIDDPMFKNYLELVPELRELINDFYNTKYGSCLKYLDKMKPILLLDIHLYKHVEILYQRIRSKALVQYFSPYQSVDMNIMASAFNTTVTLLEKEISKLIMENEIQARIDSHNKRLYARKADQRTTTFEKTVQVGSDFQNSSNSLLLRLEMLNNNISTVSNRKDNERGNWENPHHHHQMQHQMFGLFNNNNKF
Protein: DNA helicase B (D4AAN8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Thymidine phosphorylase
- Cytidine deaminase
Sequence:
MAGQGVLRELLGPLNPYKSDDEEEDCAQEEGEQDSEFVDAEELCSGGIKAGSLPGRMRVSIPDENTKEKCTVYGRFPLKDPWWRVRVRVVKHAQSSKSYQVQGFPSYFLQSDMSPPDQKSICSLFLKECNFTPERIQEFLKWVDKVSSFENLNFENLRETFRNFCRETTKKDKMQSTQSDQGDEQKLEKSFPFVIAMTALQFPKVMEFLPTLFPRHFKSLISSCSETVLGHIEEALGTQPWKLGFRRITYREMKLLSCEASWTSFSQCPSLLQLMTALQKNALVLYSKLRQTCREDGHTYIKVKDLTWGLSEHMSFEEACQSLDFLRTIDVITYEKDFIFLSELYQAEHDIASFICELMNRPPWHLKVDVRNVLASIGGAKSTDSGSTEAVEGSKPDEVEVEVAAEQGDSVLGAQDSGDHVRSNGEHVTSAEINRVPLDRDQVVALETICTNAVTVLSGKGGCGKTTIVSRLFKHVEQLEEREVQQACEDFEQDQGASEEWLDFPKQSPAGVDKAIEVLLTAPTGKAAGLLRQKTHLPAYTLCQVNYSFYMWKKNEADKPWKFSTVRVLVVDEGSLVSVAIFKSVLKLLREHSKLSKLVILGDVRQLPSIEPGNMLQDVFETLKSRQCAIELKTNHRTESQLIVDNAARISRRQFPEFDAEINISDNSTLPNSIQDKTFIFVRLPEEDSSSQSSKGKHQADLYSAVKTLLQGKDFCSPESAKTSQFIAFRRQDCDLINDCCSKHYTDHLIKDHKKKLIFAVGDKICCTRNAYLSDLLPDRDQEANGKGFGDAPDDNAKGKQDFESSIRLCNGEIFFITRDVTDVTSKRKRLLTISNDAGLEVTVDFNKLMTNCQIKHAWARTIHTFQGSEEKTVAYVVGKAGRQHWQHVYTAVTRGRSRVYIIAEESELRSAIRKRSFPRQTRLKHFLQKKLSSSCASSEGLPSQPSSPRVGGRPDTQPLASPLCTTPGSKATANSARGEASPATKERFALDGRWLSTCFSDMDTDEESEQLRGSKRTGDGFPFEEESPSKFRMVEESSPQVSSIFQSLRLNNLTRRQLFKPSDNQETAKSGVVDHTNNASNQETEP
Protein: Ras-related protein Rab-15 (EC 3.6.5.2) (P59190)
Organism: Homo sapiens (Human)
Function: May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Rab15 effector protein
- MICAL-like protein 1
Sequence:
MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELALAELEEEEGKPEGPANSSKTCWC
Protein: receptor protein-tyrosine kinase (EC 2.7.10.1) (F1MAJ0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MAVRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDLATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRNGFYLAFQDYGGCMSLIAVRVFYRKCPRVIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKQELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIKEKLPLIVGSSAAGVVFVIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFTNAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEV
Protein: Extraembryonic, spermatogenesis, homeobox 1 (Homeobox protein SPX1) (Homeodomain protein EPX) (O88933)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Sequence:
MESHKKCPCCYCTDLKTFVGAVKEETLQDPQPSLSSTLLEGADYQENAESETTFYSDFGASPKEEEVEMENSLFNSMFLEEANYQEPEGFEPSRGEAAAPVAEAPQAWNGNENLGGGFLESNAQLGEADAAPVRQSLMRPLMQPVAQSSPQPLPANPLQAPQQPEEQEEEEEEQPGEEQPQQEPKPRRYRICFTPIQLQELEAFFQRVQYPDLFARVELARRLGLPEPRVQVWFQNRRAKWRRLRRAQAFRNMVPVAMSPPVGVYLDDHYGPIPIVEVIWKCYPMVPRPMHPQMMPLPPRPPPGFRMPPPFRPPPLPPFPWPPVPPDAHIPNAAREYNPFPFPFPFPFPFPNPFPNPNPNPNPNPNPNPNPNQNFAGPRYRY
Protein: Uncharacterized protein (Q57YS0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNALSGKFTCAVLLTSDPSAVGSSTKVSVGVQNIAVVLQHQENDIPLIESVASHIQRFCAIYNISCVDCGRDIASLLKESAHVVVVRCEDRAATGEVSTQLLQQTSEPIVIVLEIDCSSPSKWDIRDSESNSGWKWLQPTPSCLAELQKHGGCSSGVWLQAAMRCSKPVVRVQLPPSSQTSVPWASAVTLDGLMREVGYKVGCLPKYGS
Protein: (-)-alpha-pinene synthase 1, chloroplastic (EC 4.2.3.119) ((-)-beta-pinene synthase 1) (EC 4.2.3.120) (Terpene synthase TPS-Pin-1) (PgTPS-Pin-1) (F2XF95)
Organism: Picea glauca (White spruce) (Pinus glauca)
Function: Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens. Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (1S,5S)-beta-pinene.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MALVSIAPLASKSCLHKSLSSSAHELKTICRTIPTLGMSRRGKSATPSMSMSLTTTVSDDGVQRRMGDFHSNLWNDDFIQSLSTSYGEPSYREQAERLIGEVKKMFNSMSSEDGELINPHNDLIQRVWMVDSVERLGIERHFKNEIKSALDYVYSYWSEKGIGCGRESVVADLNSTALGLRTLRLHGYAVSADVLNLFKDQNGQFACSPSQTEEEIRSVLSLYRASLIAFPGEKVMEEAEIFSAKYLEEALQKISVSSLSQEIRDVLEYGWHTYLPRMEARNHIDVFGQDTQNSKSCINTEKLLELAKLEFNIFHSLQKRELEYLVRWWKDSGSPQMTFGRHRHVEYYTLASCIAFEPQHSGFRLGFAKTCHIITILDDMYDTFGTVDELELFTAAMKRWNPSAADCLPEYMKGMYMIVYDTVNEICQEAEKAQGRNTLDYARQAWDEYLDSYMQEAKWIVTGYLPTFAEYYENGKVSSGHRTAALQPILTMDIPFPPHILKEVDFPSKLNDLACAILRLRGDTRCYKADRARGEEASSISCYMKDNPGVTEEDALDHINAMISDVIRGLNWELLNPNSSVPISSKKHVFDISRAFHYEYKYRDGYSVANIETKSLVKRTVIDPVTL
Protein: GTP-binding protein 2 (GTP-binding-like protein 2) (Q3UJK4)
Organism: Mus musculus (Mouse)
Interaction partners:
- Protein pelota homolog
- Ribosome-recycling factor, mitochondrial
- DDB1- and CUL4-associated factor 17
Sequence:
MDSRVSELFGGCCRPGGGPAMGGNLKARGAGGSSSCGGPKGKKKNGRNRGGKANNPPYLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHRMAEKVGADITVLREREVDYDSDVPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKVDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAITAGEAQATMGF
Protein: Hydrogenase, putative (Q729F1)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Hydrogenase, putative
- Hydrogenase, iron-sulfur cluster-binding subunit, putative
- Heterodisulfide reductase, A subunit
- Heterodisulfide reductase, C subunit
- Heterodisulfide reductase, B subunit
- Rubrerythrin diiron-binding domain-containing protein
- Alcohol dehydrogenase, iron-containing
Sequence:
MMSFARYIARGELARALDLMARGRVAYAPRREADAVVFRPRAEGEEPLLARATVPPKGIIFPQSERLFAFIREKDPNDPGHTTVRLDATADIPPALIFGGRPCDARGFHIFDRVYLNGPHRDPYYAARRDATVVVTLACAKPCSTCFCHWTGCGPADTTGSDILMTPVEGGFVAQAVTPRGQEVLEGASLPEAGADRVMAAEAVHTATLSALEAQNPAPDLSTTPRRLRERFDDSGFWRAMSDKCLACGACTYLCPTCYCFNITDENDGGDGMRGRRLRSWDNCMSSLFTREASGHNPRMGKALRLRNRVGHKFSYYPDLHEGIVSCNGCGRCITGCPVSVDIREMVVRATEPSEETPNA
Protein: tRNA-splicing ligase RtcB (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) (Archaeal 3'-phosphate RNA splicing ligase) (Q8ZY09)
Organism: Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
Function: Essential for tRNA splicing and maturation. Acts by directly joining spliced tRNA halves to mature-sized tRNAs. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends (By similarity).
Interaction partners:
- Protein archease
- RNA 3'-terminal phosphate cyclase
- Peptide chain release factor subunit 1
Sequence:
MRNIPINKINDYVWEIPPGVKPCQKVPVRIYADSVLLEKMKSDMTLEQGINVGCLPGIYRWSIVLPDAHQGYGFPIGGVAAIDAEEGVISPGGIGYDINCGVRVLRTNLTEEDVRPKLKELVDTIFRLVPPGVGGTGHLRLSPSEFERVLAEGVEWAVQKGYGWAEDMEYIEERGSWKLADPSKVSEKAKARGRDQLGTLGSGNHFLEIQVVDKIYDEKIAKLFGIEREGQVVVMIHTGSRGFGHQVATDYLLIMERKMRQWGLNLPDRELAAAPLKDKVAEDYIKAMASAANFAWTNRHIIMHWVREAFKKVFGSIEKVGLEVVYDVAHNIAKLEEHVVDEKGTVRKVWVHRKGATRAFPPGRSEIPAKYREVGQPVLIPGSMGTASWILVGTHDAMRLTFGTAPHGAGRVLSREAAIRMYPPHKVQEEMAKRGIIVRSAETEVISEEAPWAYKDVDRVVEAAHQVGFAKKVVRQRPIGVVKG
Protein: Grancalcin (C9JWQ8)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
Sequence:
MWRRQEEVLPKINLTSCGFPNTNLFPWEFGGGFEKFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA
Protein: Mexicain (EC 3.4.22.-) (P84346)
Organism: Jacaratia mexicana (Wild papaya) (Pileus mexicanus)
Function: Cysteine protease.
Subcellular location: Secreted.
Interaction partners:
Sequence:
YPESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCEYRSHGCDGGYQTPSLQYVVDNGVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPANDEISLIQAIANQPVSVVTDSRGRGFQFYKGGIYEGPCGTNTDHAVTAVGYGKTYLLLKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPIKGYR
Protein: Metallo-beta-lactamase domain-containing protein (O53534)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- S-nitrosomycothiol reductase MscR
- S-adenosylmethionine-dependent methyltransferase Rv2258c
- Conserved protein
Sequence:
MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAAPIIDAVGGRKVVAVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWRMTHPDKSFRAVSDGDAVRVGGTELRALHTPGHSPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFPTILRSISGRLGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH
Protein: B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9) (Q9QYE3)
Organism: Mus musculus (Mouse)
Function: Transcription factor (By similarity). Associated with the BAF SWI/SNF chromatin remodeling complex. Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes (By similarity). May play a role in hematopoiesis. Essential factor in lymphopoiesis, required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of NR2F2.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18681895}. Nucleus {ECO:0000269|PubMed:18681895}. Note=Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.
Interaction partners:
- B-cell lymphoma/leukemia 11B
- B-cell CLL/lymphoma 7 protein family member A
- AT-rich interactive domain-containing protein 1A
- Transcription factor SOX-6
- SWI/SNF complex subunit SMARCC2
- B-cell CLL/lymphoma 7 protein family member B
- Actin-like protein 6B
- SWI/SNF complex subunit SMARCC1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Sequence:
MSRRKQGKPQHLSKREFSPEPLEAILTDDEPDHGPLGAPEGDHDLLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKGVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRGLSSPRSAHGALIPTPGMSAEYAPQGICKDEPSSYTCTTCKQPFTSAWFLLQHAQNTHGLRIYLESEHGSPLTPRVGIPSGLGAECPSQPPLHGIHIADNNPFNLLRIPGSVSREASGLAEGRFPPTPPLFSPPPRHHLDPHRIERLGAEEMALATHHPSAFDRVLRLNPMAMEPPAMDFSRRLRELAGNTSSPPLSPGRPSPMQRLLQPFQPGSKPPFLATPPLPPLQSAPPPSQPPVKSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTHMHKSSPMTVKSDDGLSTASSPEPGTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEEEEEEEEEEELTESERVDYGFGLSLEAARHHENSSRGAVVGVGDEGRALPDVMQGMVLSSMQHFSEAFHQVLGEKHKRSHLAEAEGHRDTCDEDSVAGESDRIDDGTVNGRGCSPGESASGGLSKKLLLGSPSSLSPFSKRIKLEKEFDLPPAAMPNTENVYSQWLAGYAASRQLKDPFLTFGDSRQSPFASSSEHSSENGSLRFSTPPGELDGGISGRSGTGSGGSTPHISGPGPGRPSSKEGRRSDTCPSHTPVRRSTPRAQDVWQFSDGSSRTLKF
Protein: Histone-lysine N-methyltransferase, H3 lysine-79 specific (H9LAN6)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR037123, ECO:0000256|RuleBase:RU271113}.
Interaction partners:
Sequence:
MGEKLELRLKSPVGAESAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVPESKAAATEAPADSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAASAERKSKKSQSTLDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTQLHSPNPLLVAPTPPALQKLLESFRIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAASYELCNAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHPKESSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSEKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSATLEKQTGASAHGAGGAGAGSRSLAVAPTGFYAGSVAISGALASSPAPLASGMESAVFDESSGPSSLFATMGSRSTPPQHPPLLSQSRNSGPASPAHQLTASPRLSVTTQGSLPDTSKGELPSDPAFSDPESEAKRRIVFSISVGASSKQSPSTRHSPLTSGTRGDCVQSHGQDSRKRSRRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGLTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKSAPSSEPINSSKWKSTFSPISDLGLAKAVDSPLQAGSALSHSPLFSFRPSLEEPAAEAKLPTHPRKSFAGSLGAAEGPSPGTNPPNGLAFSGGLAADLGLHSFNDGASLSHKGPDVTGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNANKESGESLPLCGPSDKASLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGGPGLVTVASSAGSATPTAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVGSGAVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPNVALPPPPALLASNPEPVLLQSLASLPANNAFLPPSSAASLQPANASLSVKLASLPHKVSRPSFTVHHQPLPRLALAQAAPAAPQASTSGPSAVWVSLGMPPPYAAHLSGVKPR