wanglab/gogpt-training-data huggingface dataset:
Protein: Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I) (P00395)
Organism: Homo sapiens (Human)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:30030519}; Multi-pass membrane protein {ECO:0000269|PubMed:30030519}.
Interaction partners:
- NADH-ubiquinone oxidoreductase chain 4
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome b
- NADH-ubiquinone oxidoreductase chain 5
- Cytochrome c oxidase subunit 5B, mitochondrial
- NADH-ubiquinone oxidoreductase chain 1
- NADH-ubiquinone oxidoreductase chain 2
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase subunit 2
- Cytochrome b-c1 complex subunit 2, mitochondrial
Sequence:
MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGNLLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIGVNLTFFPQHFLGLSGMPRRYSDYPDAYTTWNILSSVGSFISLTAVMLMIFMIWEAFASKRKVLMVEEPSMNLEWLYGCPPPYHTFEEPVYMKS
Protein: General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135) (Q9ESZ8)
Organism: Mus musculus (Mouse)
Function: Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box (By similarity). Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.
Subcellular location: Cytoplasm. Nucleus. Note=Colocalizes with BTK in the cytoplasm. {ECO:0000250}.
Interaction partners:
- Tyrosine-protein kinase BTK
- cGMP-dependent protein kinase 1
- General transcription factor II-I repeat domain-containing protein 1
- cGMP-dependent protein kinase 2
- Upstream stimulatory factor 1
- Zinc finger MYM-type protein 2
- Histone deacetylase 3
- Genetic suppressor element 1
Sequence:
MAQVVMSALPAEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPEHYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVLAAEAERSMLSPSGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGPSETDGVDEKLPLSKALQGSHHSSEGNEGTEVEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPTKRLKSTEPPPPPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVVSYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNSSPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEASQLEVPVTEEIKETDGSSQIKQEPDPTW
Protein: procollagen-proline 4-dioxygenase (EC 1.14.11.2) (Q9VA61)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
- Uncharacterized protein, isoform A
- Uncharacterized protein
- IP08087p
- FI16633p1
- GH16267p
- IP12334p
- Accessory gland-specific peptide 26Aa
- HDC01001
Sequence:
MLFWRLVLLGMLYLSLSFGQLRENNAQQRFARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKWGVFKMMKRRQEYKSSMEIFANPIDTFSLIRHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFDFIDAAEGIRKMQATYQMFSSDIAKGLLDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQTDMELLRGPKLADLCRILGQVQMKQRNHEGALQAYQVALKLSPHDPEIYEEYRILEKRDLTLSDIEPIEQDKDNSHERLVLPPCCSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLLHDMISQKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFNDTTKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKNRFNGTSDRIATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWINDMGQEFTRPCVESSLSSNEVLSAERLII
Protein: U12-myrmicitoxin-Mri1a (U12-MYRTX-Mri1a) (U-MYRTX-MANr1) (A0A6G9KHD3)
Organism: Manica rubida (European giant red ant)
Function: Toxin that induces mild paralysis, and reduces survival and reproduction when injected into aphids (A.pisum). May affect various processes in the aphid, including wound healing and hemolymph coagulation. It does not increase the sensitivity of the aphids to the chemical insecticides imidacloprid, methomyl and Spirotetramat. Has no insecticidal activity when injected into blowfly (L.caesar). Does not display any antibacterial or antifungal activity.
Subcellular location: Secreted {ECO:0000269|PubMed:31557881, ECO:0000269|PubMed:32182430}.
Interaction partners:
Sequence:
MKTIELITIFAMITTLMVTVVAGDPIDPKVLESLVGK
Protein: Diencephalon/mesencephalon homeobox protein 1 (Diencephalon/mesencephalon-expressed brain homeobox gene 1 protein) (Orthodenticle homolog 3) (Paired-like homeobox protein DMBX1) (Paired-type homeobox Atx) (Q91ZK4)
Organism: Mus musculus (Mouse)
Function: Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development, neonatal survival, postnatal growth, and nursing ability.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O35137, ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}.
Interaction partners:
Sequence:
MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKVEAPASDTQLETEQPPGLPSGDPPAELQLSLSEQSASESAPEDQLDREEDSRAEEPKAEKSPGSESKVPGCKRGSPKADSPGSLAITPAAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAAVPYLGVNMAPLSSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPTGLAPASAALNSKTTSIENLRLRAKQHAASLGLDTLPN
Protein: PAR-domain protein 1, isoform M (M9PEP3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSDRERSSPTLIETGLKNLIGGRDGNYPLISGINGKSTSNSKEIICPDDKYKEEGDIWNVEAQTAFLGPNLWDKTLPYDADLKVTQYADLDEFLSENNIPDGLPGTHLGHSSGLGHRSDSLGHAAGLSLGLGHITTKRERSPSPSDCISPDTLNPPSPAESIFDIPAFSFASSGRDFDPRTRAFSDEELKPQPMIKKSRKQFVPDELKDDKYWARRRKNNIAAKRSRDARRQKENQIAMRARYLEKENATLHQEVEQLKQENMDLRARLSKFQDV
Protein: Putative ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (P87316)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity).
Subcellular location: Mitochondrion. Mitochondrion inner membrane.
Interaction partners:
- ATP synthase subunit g, mitochondrial
- ATP synthase subunit 5, mitochondrial
- ATP synthase subunit delta, mitochondrial
- ATP synthase subunit gamma, mitochondrial
- ATP synthase subunit d
- ATP synthase subunit beta, mitochondrial
- ATP synthase subunit alpha
- ATP synthase subunit 4
- ATP synthase subunit a
- ATP synthase subunit 9, mitochondrial
Sequence:
MAFAWKKNFSYSKYASICSQTVRQALKPEIKNEVKTHGDAEFLYTRWKNGAQEKTESYNSAKSADKE
Protein: Homeodomain-like superfamily protein (Similarity to DNA-binding protein GT) (Q9FGJ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Alcohol dehydrogenase transcription factor Myb/SANT-like family protein
- UMP kinase
- At4g31270
- Trihelix transcription factor ASIL1
- Trihelix transcription factor GT-1
Sequence:
MELLAGDCRKRVGDDFEEDINPFDGSDGGCGWMYGTRQMGSNGNDDALATLADLASPPQKLKPIRCGVKLPSSSEDRHPLDILAGTLDRLPEMGFGCFEAPLGSKIADVEESGQLTRGFSKEEDDSLPPLQMEFQARNRISWDGLSLSSSVDSSDSDSSPDVRKTVTGKRKRETRVKLEHFLEKLVGSMMKRQEKMHNQLINVMEKMEVERIRREEAWRQQETERMTQNEEARKQEMARNLSLISFIRSVTGDEIEIPKQCEFPQPLQQILPEQCKDEKCESAQREREIKFRYSSGSGSSGRRWPQEEVQALISSRSDVEEKTGINKGAIWDEISARMKERGYERSAKKCKEKWENMNKYYRRVTEGGQKQPEHSKTRSYFEKLGNFYKTISSGEREK
Protein: Sporulation-specific mitogen-activated protein kinase SMK1 (MAP kinase SMK1) (EC 2.7.11.24) (P41808)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for spore wall assembly. Required for proper deposition of the two outer layers of the spore wall, the chitosan and dityrosine layers. Negatively regulates GSC2, an alternate catalytic subunit of the 1,3-beta-glucan synthase (GS). Participates in a developmentally regulated signal transduction pathway that coordinates cytodifferentiation events with the transcriptional program.
Interaction partners:
- Sporulation-specific protein 2
- Mitogen-activated protein kinase SLT2/MPK1
- 1,3-beta-glucan synthase component GSC2
- Tyrosine-protein phosphatase CDC14
- Exportin-1
- Cell wall assembly regulator SMI1
- Serine/threonine-protein kinase CAK1
Sequence:
MNCTLTDNTRAINVASNLGAPQQRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNFKTDLSSSSL
Protein: Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form] (Q9Y275)
Organism: Homo sapiens (Human)
Function: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
Subcellular location: Cell membrane; Single-pass type II membrane protein.; SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 13b, soluble form]: Secreted.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 17
- Tumor necrosis factor receptor superfamily member 13C
- Tumor necrosis factor receptor superfamily member 13B
- CD40 ligand
- Tumor necrosis factor receptor superfamily member 5
- Tumor necrosis factor ligand superfamily member 12
- Immunoglobulin lambda-like polypeptide 5
- Tumor necrosis factor receptor superfamily member 3
- Tumor necrosis factor
- Tumor necrosis factor ligand superfamily member 11
Sequence:
MDDSTEREQSRLTSCLKKREEMKLKECVSILPRKESPSVRSSKDGKLLAATLLLALLSCCLTVVSFYQVAALQGDLASLRAELQGHHAEKLPAGAGAPKAGLEEAPAVTAGLKIFEPPAPGEGNSSQNSRNKRAVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL
Protein: Ribosomal RNA small subunit methyltransferase Nep1 (EC 2.1.1.-) (16S rRNA (pseudouridine-N1-)-methyltransferase Nep1) (16S rRNA Psi914 methyltransferase) (Q57977)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of pseudouridine at position 914 (Psi914) in 16S rRNA. Is not able to methylate uridine at this position.
Interaction partners:
- KH domain-containing protein MJ0443
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein uS11
- Uncharacterized NOP5 family protein MJ0694
- Small ribosomal subunit protein eS19
- RNA 3'-terminal phosphate cyclase
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS7
Sequence:
MTYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
Protein: DnaJ homolog subfamily C member 10 (DnaJ homolog subfamily C member 16) (Endoplasmic reticulum DNA J domain-containing protein 8) (Q9XWE1)
Organism: Caenorhabditis elegans
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}.
Interaction partners:
- Heat shock 70 kDa protein C
- Endoplasmic reticulum chaperone BiP homolog
- Large ribosomal subunit protein uL11m
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL14
- Endoplasmin homolog
- Heat shock protein hsp-6
- Hypoxia up-regulated protein 1
- Hypoxia up-regulated protein 1
- Heat shock protein 70
Sequence:
MRAIVLLSVLISCYLVIAEDYYELLGVERDADDRTIRKAFKKLAIKKHPDRNTDDPNAHDEFVKINKAYEVLKDENLRKKYDQFGEKGLEDGFQGGNNYQSWQFYNDNFGIYDDDQEIVTLNRADFQRMVSDSNEIWFINFYSTYCSHCHQLAPTWRKFAREIEGTIRVGAVNCAEDPQLCQSQRVNAYPSLVFYPTGEFYQGHRDVELMVDFAIQRLKSEVLHLNSENWKALSEDWEPYNRLPWVVDMCGGDHIDCLSSTTRRKLSSMLDGLANVATIDCNAEEALCSKFNPITSGVMWFPARKLVKKSQINIESMDAQEISKSVIQYLDELEDISVESLQRLLEGNDPDEPIAVWMLANDAQSTERKDFRRLPALVTTQIFKFDCSKSSEICDELLDKTKLPQFMVFKTTGGYEIDYAGSKDFHAASTFIREASKSHIHVLNRDSYEYAISGGEFYIIDYFAPWCPPCMKLLGEYRRFHTATSEDSMLHTVAIGSLDCVKYKDLCQQAGVQSYPTSIVYTPDGKTHKMVGYHNVDYILEFLDNSLNPSVMEMSPEQFEELVMNRKDEETWLVDFFAPWCGPCQQLAPELQKAARQIAAFDENAHVASIDCQKYAQFCTNTQINSYPTVRMYPAKKTKQPRRSPFYDYPNHMWRNSDSIQRWVYNFLPTEVVSLGNDFHTTVLDSSEPWIVDFFAPWCGHCIQFAPIYDQIAKELAGKVNFAKIDCDQWPGVCQGAQVRAYPTIRLYTGKTGWSRQGDQGIGIGTQHKEQFIQIVRQQLKLDEHDEL
Protein: REST corepressor 1 (Protein CoREST) (Q8CFE3)
Organism: Mus musculus (Mouse)
Function: Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624}.
Interaction partners:
- Lysine-specific histone demethylase 1A
- Histone deacetylase 1
- Histone deacetylase 2
- RE1-silencing transcription factor
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
- PHD finger protein 21A
- Paired amphipathic helix protein Sin3a
- Mediator of RNA polymerase II transcription subunit 12
- Mediator of RNA polymerase II transcription subunit 28
- CST complex subunit STN1
Sequence:
MPAMVEKGPEVSGKRRGRNTAASAASAAASAASAAASAAASAGTASASAAAAASAAAAPNNGQNKSLAAAAPNGNSGSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAAVPDFDPAKLARRSQERDNLGMLVWSPNQSLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQKREREESEDELEETNGSNPVDIEIDPNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSIKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKDETNGPANQKPVKSPESSIKIPEEEDEAASVLDVRYASAS
Protein: 40S ribosomal protein S24 (Q6FPJ9)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Small ribosomal subunit protein uS10
- 40S ribosomal protein S12
- Small ribosomal subunit protein uS9
- Candida glabrata strain CBS138 chromosome K complete sequence
- Small ribosomal subunit protein uS2
- L37
- Large ribosomal subunit protein uL5
- 40S ribosomal protein S30
- 60S ribosomal protein L6
- Large ribosomal subunit protein eL38
Sequence:
MSDSVTIRTRKVITNPLLARKQFVVDVLHPNRANVSKDELREKLAEAYKAEKDAVSVFGFRTQFGGGKSTGFGLVYNSVADAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGRRLAKKVARRNAD
Protein: LD16810p (Pimples protein) (Pimples, isoform A) (Pimples, isoform B) (Q24454)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- separase
- Mitotic spindle assembly checkpoint protein MAD2A
- Cyclin-dependent kinases regulatory subunit
- Cyclin-dependent kinase 1
- Kinetochore protein Spc25
- G2/mitotic-specific cyclin-B3
- Serine/threonine-protein kinase polo
- Cell division cycle protein 20 homolog
Sequence:
MDQILNKENTGINLPANPIKNGVPTNSVLKKPLGNLDNVMHQTPGITPFKSTSLKLEGSIAKLSLRKAPKQNVVSRDREEVRYKTNSCFLGAYVLNCEYRVVNLFNYTDFPNEKCLKNCSKPVTETWSENQEGYEGLLDQLYLDLRTLENNLENRCLPPLDFTDLPYIYNTENMEPAEPEYLLNLYPPLPNLEGIDVLF
Protein: Troponin T type 3a (skeletal, fast) (A0A060WB67)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Troponin I type 1a
- Troponin I, slow skeletal muscle
- Troponin I, fast skeletal muscle
- Troponin I, fast skeletal muscle
- Troponin I, fast skeletal muscle
- Troponin T type 3a
- Troponin I, skeletal, slow c
- Troponin I, slow skeletal muscle
- Troponin I, slow skeletal muscle
- Troponin I, slow skeletal muscle
Sequence:
MQTDSFGNTIVLLLSFSEINVYIRGGEGEAIAEEVVEEVVEEVVEEEVVEEEVEVAPEAAPEPEAEPEPEPEPEAEPEPEPEAEEVVEEEAQKPQFKVPKIPDGDKVDFDDIQKKRQNKDLVELQALIDAHFEHRKKEEEELIALKERIEKRRAERAEQNRIRSEKEKERAARREEERLKREEADAKKKADEDAKKKSALSSMGSNYSSHLQKADSKRGGKKETEREKKKKILAGRRKALNIDHLNEEKLKEKAKELHEWMQTLESEKFDHIERLKRQKYEVTTLRKRVEELSKFSKKGKTVRRK
Protein: Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18Hs) (Cytochrome c oxidase assembly protein 18) (Q8N8Q8)
Organism: Homo sapiens (Human)
Function: Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2. Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:16212937, ECO:0000269|PubMed:28330871}; Multi-pass membrane protein {ECO:0000269|PubMed:16212937}.
Interaction partners:
- Cytochrome c oxidase subunit 2
- Protein transport protein Sec61 subunit alpha isoform 1
- Protein transport protein Sec61 subunit alpha isoform 2
- Cytochrome c oxidase assembly protein COX20
- MICOS complex subunit MIC60
- Protein SCO1 homolog
- Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial
- Cytochrome c oxidase assembly protein COX11
- Cytochrome c oxidase assembly factor 6 homolog
Sequence:
MLCRLGGRWLRPLPALQLWARDLPLAPVPTSGAKRPTLPVWAVAPVSAVHANGWYEALAASSPVRVAEEVLLGVHAATGLPWWGSILLSTVALRGAVTLPLAAYQHYILAKVENLQPEIKTIARHLNQEVAVRANQLGWSKRDARLTYLKNMRRLISELYVRDNCHPFKATVLVWIQLPMWIFMSFALRNLSTGAAHSEGFSVQEQLATGGILWFPDLTAPDSTWILPISVGVINLLIVEICALQKIGMSRFQTYITYFVRAMSVLMIPIAATVPSSIVLYWLCSSFVGLSQNLLLRSPGFRQLCRIPSTKSDSETPYKDIFAAFNTKFISRK
Protein: Adenylate isopentenyltransferase 5, chloroplastic (AtIPT5) (EC 2.5.1.112) (Adenylate dimethylallyltransferase 5) (Cytokinin synthase 5) (Q94ID2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in cytokinin biosynthesis. Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:14726522}.
Interaction partners:
- Cytokinin hydroxylase
- Cytokinin hydroxylase
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic
- Isopentenyl-diphosphate Delta-isomerase I, chloroplastic
- Isopentenyl-diphosphate Delta-isomerase II, chloroplastic
- Cytokinin dehydrogenase 1
- Cytokinin dehydrogenase 5
- Cytokinin dehydrogenase 7
- Cytokinin dehydrogenase 3
- Cytokinin dehydrogenase 6
Sequence:
MKPCMTALRQVIQPLSLNFQGNMVDVPFFRRKDKVVFVMGATGTGKSRLAIDLATRFPAEIVNSDKIQVYKGLDIVTNKVTPEESLGVPHHLLGTVHDTYEDFTAEDFQREAIRAVESIVQRDRVPIIAGGSNSYIEALVNDCVDFRLRYNCCFLWVDVSRPVLHSFVSERVDKMVDMGLVDEVRRIFDPSSSDYSAGIRRAIGVPELDEFLRSEMRNYPAETTERLLETAIEKIKENTCLLACRQLQKIQRLYKQWKWNMHRVDATEVFLRRGEEADEAWDNSVAHPSALAVEKFLSYSDDHHLEGANILLPEISAVPPLPAAVAAISR