wanglab/gogpt-training-data huggingface dataset:
Protein: N-terminal kinase-like protein (105 kDa kinase-like protein) (Mitosis-associated kinase-like protein NTKL) (SCY1-like protein 1) (Q9EQC5)
Organism: Mus musculus (Mouse)
Function: Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum. Involved in the maintenance of the Golgi apparatus morphology. Has no detectable kinase activity in vitro.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:11118629, ECO:0000269|PubMed:12783284}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250}. Golgi apparatus, cis-Golgi network {ECO:0000250}. Note=Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner. {ECO:0000250}.
Interaction partners:
- RAB6-interacting golgin
- Coatomer subunit alpha
- Coatomer subunit beta
- Coatomer subunit delta
- Coatomer subunit beta'
- Coatomer subunit epsilon
- Coatomer subunit gamma-2
- Coatomer subunit zeta-1
- Coatomer subunit zeta-2
- Divergent protein kinase domain 2A
Sequence:
MWFFARDPVRDFPFELSPEPPEGGPPGPWILHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEKCLHIVTEAVTPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPSKGIPELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVFNGSLPRAAALRNPGKIPKSLVTHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDSFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKSLRAEEYQEKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVTHGFLDTNPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDDQGPIRCNTTVCLGKIGSYLSASTRHRVLTSAFSRATKDPFAPSRVAGVLGFAATHNLYSMDDCAHKILPVLCGLTVDPEKSVRDQAFKTIRSFLSKLESVSEDPTQLAEVEKDVHAASSPGTGGAAASWAGWAVTGVSSLTSKLIRAHPTPVPSDTTVPQRPVPEGNPAPAPALAQAIPATSGHWETQEDKDTAEDSATADRWDDEDWGSLEQEAESVLAQQDDWSAKGQGSRAGQINHPDHKSLESHWSSWEVEGSWDQGWQEPSSVEPPPEGTRLASEYNWGGAEPSDKGDPFAALSVRPSAQPRPDPDSWGEDNWEGLEAESRQVKAELARKKREERRREMEAKRAEKKTTKGPMKLGARKLD
Protein: Muscarinic acetylcholine Receptor, B-type, isoform B (A0A0B4LGX5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MRSLNKSAGEEELTGLNGNSSDSIYTIKNKWITDWSLRRERDKLCSFIFKRVLTHTECKRLLEAAKIYGESSDFNSWPVNEQLQWYRNFDVNNTNLLLAVRNQSSDGGSTMSGSSSDSEILGPVLPPFALWQTILIAICLAICIILTVGGNILVLLAFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTGKRDLLPGQCAVQFLKDPIFNTALIIGYYWTTLIVLFVLYAGIYKTAYDMQKRSEAKQRKMQSMVALSAGAMSGMAGHAAGIGVIEEKILKTKVELAGDQTDLDSACTTVIKRLSGSGQANPLAVATEEVEKMTPEQRRASAAKIQEEAKKREAAVDAEKSERSSSPAFDSDEESSVNQAQQLITQQKLNNMRKRSSIGLVFGAQAALLATRGKGIEDFAKVRRESCIEAICLLDVPGKLAADCPHRRASSPMETSSKDAILYSPMPPMPLSPKVKTSTPQTGTPQSAAGVTPPVPLERIEERETSDSNTNKMPSTSGTTSSTGGVGGGGEQDGVGATKKNAGDDDANREEKSLAASRNSSKRAFIHSIGKHFKSKKALPLILGVGGRQKSKSENRARKAFRTISFILGCFVACWTPYHVLALVEGFCRHPPCINEHLYMFSYFLCYANSPMNPFCYALANQQFKKTFTRILKGDLHMT
Protein: Cytochrome P450 705A1 (EC 1.14.-.-) (Q0WQ07)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cleaves the arabidiol side chain at C15 to form 14-apo-arabidiol and a side-chain fragment. Involved in the biosynthesis of the volatile homoterpene (E)-4,8-dimethyl-1,3,7-nonatriene (DMNT) in roots. Involved in the production of DMNT by degrading the triterpene arabidiol. May be involved in the defense again the fungal root pathogen Pythium irregulare by producing DMNT.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cysteine-rich receptor-like protein kinase 29
- Cysteine-rich receptor-like protein kinase 28
- Arabidiol synthase
Sequence:
MDAIVVDSQNCFIIILLCSFSLISYFVFFKKPKVNFDLLPSPPSLPIIGHLHLLLSTLIHKSLQKLSSKYGPLLHLRIFNIPFILVSSDSLAYEIFRDHDVNVSSRGVGAIDESLAFGSSGFIQAPYGDYWKFMKKLIATKLLGPQPLVRSQDFRSEELERFYKRLFDKAMKKESVMIHKEASRFVNNSLYKMCTGRSFSVENNEVERIMELTADLGALSQKFFVSKMFRKLLEKLGISLFKTEIMVVSRRFSELVERILIEYEEKMDGHQGTQFMDALLAAYRDENTEYKITRSHIKSLLTEFFIGAADASSIAIQWAMADIINNREILEKLREEIDSVVGKTRLVQETDLPNLPYLQAVVKEGLRLHPPTPLVVREFQEGCEIGGFFVPKNTTLIVNSYAMMRDPDSWQDPDEFKPERFLASLSREEDKKEKILNFLPFGSGRRMCPGSNLGYIFVGTAIGMMVQCFDWEINGDKINMEEATGGFLITMAHPLTCTPIPLPRTQNSLISHL
Protein: Uncharacterized protein C12G12.07c (Q09871)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Probable thymidylate synthase
- Protein sum2
- ATP-dependent RNA helicase dbp2
- ATP-dependent RNA helicase mss116, mitochondrial
- Ribosome-associated protein oga1
Sequence:
MPSQGNNKNSENITQNPIEGELGSVIVEHLTKRIRNFTKKKQKILKLEEIAASDSNSLNDDQRKALQGKDAVLTTLNELKELLSQIDATRIRDEKHKRQFEATENAKRKEEIEAQYREGYDTAQKQVSSLVRFLRFASHNCVHPSDDAPFNSAVEKLLVIVYEGTEKSEKAVADLNDSSTDVVPESEVSFQTISSRVDNFFAAPLPSEQAEELIEDDYAEQPEQAVGQPIEQQSISDDEARQTNRPLNRGIQFLNESEIEGQHVEEPALPSETSVPANSTLQVPTENVEVDVLGKDGTNIYPTQNQVVEQKQMQQKLDSMSPEWYQAADPSNGVVDGTPKLNSNTRGSSKRPSVNRSQGSGQRGRGGRGFYRGGRGRGGFFNRSKRGQYSNSNNSTSQPSPNAELSNFNPVA
Protein: Uroporphyrinogen-III C-methyltransferase (Urogen III methylase) (EC 2.1.1.107) (SUMT) (Uroporphyrinogen III methylase) (UROM) (P36150)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Siroheme synthase involved in methionine biosynthesis.
Interaction partners:
- Siroheme biosynthesis protein MET8
- Sulfite reductase flavoprotein component
- Porphobilinogen deaminase
- Sulfite reductase subunit beta
- Uroporphyrinogen decarboxylase
- Uroporphyrinogen-III synthase
- Phosphoadenosine phosphosulfate reductase
- Adenylyl-sulfate kinase
- Sulfate adenylyltransferase
- Zinc finger protein FZF1
Sequence:
MVRDLVTLPSSLPLITAGFATDQVHLLIGTGSTDSVSVCKNRIHSILNAGGNPIVVNPSSPSHTKQLQLEFGKFAKFEIVEREFRLSDLTTLGRVLVCKVVDRVFVDLPITQSRLCEEIFWQCQKLRIPINTFHKPEFSTFNMIPTWVDPKGSGLQISVTTNGNGYILANRIKRDIISHLPPNISEVVINMGYLKDRIINEDHKALLEEKYYQTDMSLPGFGYGLDEDGWESHKFNKLIREFEMTSREQRLKRTRWLSQIMEYYPMNKLSDIKLEDFETSSSPNKKTKQETVTEGVVPPTDENIENGTKQLQLSEVKKEEGPKKLGKISLVGSGPGSVSMLTIGALQEIKSADIILADKLVPQAILDLIPPKTETFIAKKFPGNAERAQQELLAKGLESLDNGLKVVRLKQGDPYIFGRGGEEFNFFKDHGYIPVVLPGISSSLACTVLAQIPATQRDIADQVLICTGTGRKGALPIIPEFVESRTTVFLMALHRANVLITGLLKHGWDGDVPAAIVERGSCPDQRVTRTLLKWVPEVVEEIGSRPPGVLVVGKAVNALVEKDLINFDESRKFVIDEGFREFEVDVDSLFKLY
Protein: Peroxisomal membrane protein PEX32 (Peroxin-32) (P38292)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Peroxisomal membrane protein PEX30
- Peroxisomal membrane protein PEX28
- Peroxisomal membrane protein PEX29
- Clathrin adapter accessory protein LAA2
- Outer spore wall protein LDS1
Sequence:
MDTNSKTKVQTENKKIKAKFIHNHGQKPSLIQITPPMISSTLFHAYPLLLIFDNALANIMWLSDDKCLTFIYLTSIWLTISFFIPVETEASHFLPFTKILRLWLGIISGAFLFLSFMYYIVSLIASLRDTEPPTLDEIVVLLESVLDKLEVLRNELNVWKKLKLSFDGVNKECSGKRLFCRLFLFGTIFQIIIMRYISPGTYTRFFIITGLIYNTSSFQATLRLLWRFTAVRNFYYLGIESFKISSFLPKHLKMEQIIPLSQGRAITVPLVEVLPKLLRDKKGDDHIHILQLLLNEQKDNFGNEDLKILEIEVYENQRRWYQNKNWSTKLLPYERQNYCIEIKNTDGTLTMRSCLPPDGLGEEELPNNWHWINDNWDGTDWIYSDSAWKEIGQYSSLESFTRSRKWKRRLFHL
Protein: Putative glutathione S-transferase alpha-1 (EC 2.5.1.18) (GST class-alpha 1) (Q55FF3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Interaction partners:
- Glutathione synthetase
- Putative glutathione S-transferase alpha-5
- Glutathione S-transferase
- Glutathione S-transferase
- Glutathione reductase
- Uncharacterized protein
- Glutathione transferase
- Putative glutathione S-transferase alpha-4
- Putative glutathione S-transferase alpha-3
- Probable microsomal glutathione S-transferase
Sequence:
MTTNKPSFSYFKVLVLGQLPRFTLNYFGTDFTDNYVESIDDEFRKTLKFGQLPLFVDSDGFRLTQTDAICKYIAAKHDFLGKSIKERAIVDETIAAVHDDVIIPGYKVGKGVEDKKVIDTIISRHFTTFENVLAENKFIAGGDNYTLADLYVFVAYHYYKHLGHSEKFQNKFPHLEALQAHFESNKGIAEYIKNRPDSGRGI
Protein: Protein HUA2-LIKE 2 (HUA2-like protein 2) (F4IN78)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor that acts with partial redundancy with HULK1 and HULK3. Plays diverse and essential roles in the control of plant development, physiology and flowering time.
Subcellular location: Nucleus {ECO:0000269|PubMed:25070081}.
Interaction partners:
- Uncharacterized protein At1g51745
- Tudor/PWWP/MBT superfamily protein.
- Probable apyrase 7
- Dehydrogenase/reductase SDR family member FEY
- Uncharacterized protein At5g66000
- Sucrose transport protein SUC9
- Nodulin homeobox
- Calmodulin-binding protein 60 B
- KH domain-containing protein HEN4
Sequence:
MAPSRRKGGGKAAAVAAACRKRKVGDLVLAKVKGFPAWPAVVSEPEKWDASPDSKKVFVHFFGTQQIAFCNPGDVEAFTEERKQSLLTRRHAKGSDFVRAVKEIIESYEKLKQQERASDPKSAEEGTLGSAENTTLMPQVIEIPTATSLTQMNSDPSHGRDESTLLNEDASAAEQMLALRDNSGPRNKACDSAVVKEPRKIATYSSRKRNGGVRSQNCAPQNETCPVQRSKSPSRLQTEKLQSSMLQNSDGGQTIDDVEDGALRREKRIRRSSGHSESDDVATSSLNSHGSDEENASEIATVESDNNRNEGNGVDSGSKVEQIDIGGKFLEGDYDLNKGLNFQINIMVKRKKRKPTRKRGTSDVVDPQAKVEGEAVPEAGARNNVQTSQNSHEKFTERPCEENGDEHLPLVKRARVRMSRAFYGNHEANSSLQAEERSPKDTVVSATAQTSPSDIISSHDTFAVEESKFFEVSAKLSGDMVNVAPSPVEKSHDGMSPSEACVQTVREREYAMGWNELSKTPDDKSAGPQYNQVSSLPAGEAQTASVPEAVCPEVLKLLTSESDLPAVQYCQVAKIEPSMDPNTVDSSANNASEICSLSIPSQLSGQDRSNDQDACVSLENSREYLNEEGSKIDACVAQVVQSEAIEHSPSSCLVVNKQETENMPKTVNMLLKEGHGSLGEECAIVEPAQCTPNLPISATESDVIVGENVPLNEIGCTKCEDAVEDSRQLKMIGETNDQKQQVQTNNSVLVSENLSREKMSFSPAITADTPARGTPHSSSVYYHISTSESANDMQNNSSGSPNIPTGEKKNDCDAIVKEEEKIETGVCQGQKVVSCDVQSTRESYEDALCSLVRTKESIGRATCLAMDLMKFGVSAKAMEILAHTLESESNLKRRVDLFFLVDSIAQCSKGLKGDTGCVYLSAIQVILPRLLAAAVPAGATTQENRKQCLKVLKLWLERRILPESIVRHHIRELDSHSIVPACLYSRRSARTERSLDDPVRDMEDMLVDEYGSNSTLQLPGFCMPALLKDEEGGSDSEGGCDSEGGSDSDGGDFESVTPEHESRILEENVSSSTAERHTLILEDVDGELEMEDVAPPWGTENCTHTDQADNTKVSNCQLGQQHRPVFGTSHQHMSLSSPPLPSSSPPPPPAPPSQQGECAMPDSYLNGFENGGYRNVHGDQQAGPLRMNPPLSGSTMHYQGPESSYISGVQLTNSIPQADGSNFQHRPYPSHPHPHPPPPPPPPQHQFSFREPGHVLKSHRDAPSYSHRSHYVPNCDERNFHDNHERMRHAPFENRDNWRYPPSSSYGSRYQDEHKAPYPSSSYNGVRWDNPPRQYNNRPSFHPKPHSEGPAPVGMRDPGMWHQRSD
Protein: Sulfate transporter 2.1 (AST68) (O04722)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Low-affinity H(+)/sulfate cotransporter that may be involved in root-to-shoot translocation of sulfate. Plays a central role in the regulation of sulfate assimilation.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- ATP sulfurylase 4, chloroplastic
- ATP-sulfurylase 3, chloroplastic
- ATP sulfurylase 1, chloroplastic
- 5'-adenylylsulfate reductase 2, chloroplastic
- 5'-adenylylsulfate reductase 3, chloroplastic
- Probable ubiquitin-conjugating enzyme E2 24
- 5'-adenylylsulfate reductase 1, chloroplastic
- Assimilatory sulfite reductase
Sequence:
MKERDSESFESLSHQVLPNTSNSTHMIQMAMANSGSSAAAQAGQDQPDRSKWLLDCPEPPSPWHELKRQVKGSFLTKAKKFKSLQKQPFPKQILSVLQAIFPIFGWCRNYKLTMFKNDLMAGLTLASLCIPQSIGYATLAKLDPQYGLYTSVVPPLIYALMGTSREIAIGPVAVVSLLISSMLQKLIDPETDPLGYKKLVLTTTFFAGIFQASFGLFRLGFLVDFLSHAAIVGFMGGAAIVIGLQQLKGLLGITNFTTNTDIVSVLRAVWRSCQQQWSPHTFILGCSFLSFILITRFIGKKYKKLFWLPAIAPLIAVVVSTLMVFLTKADEHGVKTVRHIKGGLNPMSIQDLDFNTPHLGQIAKIGLIIAIVALTEAIAVGRSFAGIKGYRLDGNKEMVAIGFMNVLGSFTSCYAATGSFSRTAVNFAAGCETAMSNIVMAVTVFVALECLTRLLYYTPIAILASIILSALPGLININEAIHIWKVDKFDFLALIGAFFGVLFASVEIGLLVAVVISFAKIILISIRPGIETLGRMPGTDTFTDTNQYPMTVKTPGVLIFRVKSALLCFANASSIEERIMGWVDEEEEEENTKSNAKRKILFVVLDMSSLINVDTSGITALLELHNKLIKTGVELVIVNPKWQVIHKLNQAKFVDRIGGKVYLTIGEALDACFGLKV
Protein: Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (Tyrosine kinase receptor CEK1) (P21804)
Organism: Gallus gallus (Chicken)
Function: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=After ligand binding, both receptor and ligand are rapidly internalized. Can translocate to the nucleus after internalization, or by translocation from the endoplasmic reticulum or Golgi apparatus to the cytosol, and from there to the nucleus (By similarity). {ECO:0000250}.
Interaction partners:
- Fibroblast growth factor 2
- Fibroblast growth factor 8
- Fibroblast growth factor 1
- Anosmin-1
- Fibroblast growth factor 10
- Fibroblast growth factor
- Fibroblast growth factor
- Fibroblast growth factor
- Fibroblast growth factor
- Fibroblast growth factor 4
Sequence:
MFTWRCLILWAVLVTATLSAARPAPTLPDQALPKANIEVESHSAHPGDLLQLRCRLRDDVQSINWVRDGVQLPENNRTRITGEEVEVRDAVPEDSGLYACMTNSPSGSETTYFSVNVSDALPSAEDDDDEDDSSSEEKEADNTKPNQAVAPYWTYPEKMEKKLHAVPAAKTVKFKCPSGGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENKYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFVCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGISHHSAWLTVLEATEQSPAMMTSPLYLEIIIYCTGAFLISCMVVTVIIYKMKSTTKKTDFNSQLAVHKLAKSIPLRRQVTVSADSSSSMNSGVMLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLILGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEYLDLSVPLDQYSPGFPATRSSTCSSGEDSVFSHDPLPDEPCLPRCPPHSHGALKRH
Protein: Tryptophanase operon leader peptide (TnaC) (P0AD89)
Organism: Escherichia coli (strain K12)
Function: Required for tryptophan-regulated expression of the tna operon. In the presence of free L-Trp release of this nascent peptide by release factor 2 is inhibited and the ribosome stalls with the last amino acid in the P site and a UGA stop codon in the A site. This prevent transcripiton termination factor Rho binding, and thus allows transcription and translation of TnaA and TnaB.
Interaction partners:
- Tryptophanase
- Peptide chain release factor RF2
- Low affinity tryptophan permease
- Secretion monitor
- Alternative ribosome-rescue factor A
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL22
- Transcription termination factor Rho
- Large ribosomal subunit protein bL34
- Small ribosomal subunit protein uS15
Sequence:
MNILHICVTSKWFNIDNKIVDHRP
Protein: Large ribosomal subunit protein bL20c (50S ribosomal protein L20, chloroplastic) (P56794)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein bL36c
- Large ribosomal subunit protein uL2cz/uL2cy
- Large ribosomal subunit protein uL16c
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein uS14c
- Large ribosomal subunit protein uL14c
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Large ribosomal subunit protein bL31c
- DNA-directed RNA polymerase subunit alpha
- Small ribosomal subunit protein bS16cz
Sequence:
MTRIKRGYIARRRRTKLRLFASSFRGAHSRLTRTMTQQRIRALVSAHRDRGKRKRDFRRLWITRINAVIHEMGVFYSYNEFIHNLYKKQLLLNRKILAQIALLNRSCLYTISNDIKK
Protein: General secretion pathway protein B (Q01563)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Function: Out proteins are required for the translocation of pectate lyases and cellulases across the outer membrane.
Subcellular location: Cell inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKNTPEVKASPQTGYRIPGYLLVVYALLLFTLGWFGHQRWADISPIPLSTSAAAIAAPPTKVGMVPASTAVTADENHPGSLHAAAENSATQTAASGSQTSASSQEATPDTKPAKLVTGWQTAKPGELPYIAFSAHVYTSAPDKRSVTLNGERYREGDSPYQGLVIEQIEQDMVIFSFNGEPFILDSLQDWPGGKPGDDAAQGNEQEPTSKPEQTVRTTKK
Protein: P-type phospholipid transporter (EC 7.6.2.1) (A0A8I5Y6F1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MELEEDLNGRADKNFSKMGKKSKKEKKEKKPAVSVLTMFRYAGWLDRFYMLLGTLAAIIHGIALPLMMLVFGDMTDSFANVGNNRSMSFYNATDIYAKLEDEMTTYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYTIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFSIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKDVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIELGNEACESKDGIDNVDMSSKDSGSSLIRRRSTRKSIRGPHDQDGELSTKEALDDDVPPASFWRILKLNSTEWPYFVVGVFCAIINEACNQHSP
Protein: Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappaB kinase subunit beta) (EC 2.7.11.10) (Cactus kinase IKK) (IKK-like protein) (Immune response deficient protein 5) (Lipopolysaccharide-activated kinase) (DLAK) (Q9VEZ5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for the activation of the NF-kappa-B factor Relish (Rel) by acting as an essential signaling component in transmitting the lipopolysaccharide (LPS) signal leading to cact degradation, which is required for direct activation of Rel. Phosphorylates inhibitors of NF-kappa-B (cact) thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the NF-kappa-B inhibitor. Essential for antibacterial immune response. Also required for antiviral immune response.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- NF-kappa-B essential modulator
- Nuclear factor NF-kappa-B p110 subunit
- GH01161p
- LD40663p
- RAC serine/threonine-protein kinase
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Gigas, isoform A
- Forkhead box protein O
- LD23779p
- Mitogen-activated protein kinase kinase kinase 7
Sequence:
MITVVFCFSDCHGGIQILGRMSSVNKIKLNENNKMHSFGNWERCRNLGEGGFGLVIHWRNRTTGREIATKHIKEMGALSADQQVKLSERWNKELNWSRQFKNFPHIVAGVDIEDPDFLEYLNGMFSAKLPVIVLEYCNGGDVRKRLQSPENANGLTEFEVRQILGALRKALHFLHSQCGICHRDLKPDNIVIQRGVDGKKIYKLTDFGLARGTPDQTMVQSVVGTRHYYAPEVVENGFYNSTVDLWSFGVIAYELVTGELPFIPHQTLKNIILNLIKKPAKCIAITEDPEDNTRFVNQFELPQTHHLSRPWAAQFTKWLASPLNSNYKERGQLAANNVPVVFADLDKILNMNVLTIFAVNNCERLEYAVSAEMTMKDLIALIVLDTGMDEKELYFVLPTSHPHKTITPKSTPLQLYVEEWSDTSKDSRKWTKRSNPPVMLYIFQVKKECDYKIPEPILSILSRKFIANKFKTKERWLQKRVVLDMLYVLTKEQARYEMLVSGINERALSLEDEMMENSFIDSIDKQRIIISFAYDQLTSLLKEAQAKIPSRQLISSAQWEKLNRNYNFIIQSAKSIRSFLEACLREAKDMVKTTNQLRKEVCEKDLFDCARFYKKYLCNGAIISPSELNNDAEEFAKSRFKLYNEGEARHLPKSIDHMHYLYFKTKESIPVLLQQFCDIKKEIFQINLQMLMSASSTPPPKLELSAAMDRLAISSGSPSSDPFDSLRTINAIEEAERINNILVNEMKIDHY
Protein: mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4) (Q9UKD2)
Organism: Homo sapiens (Human)
Function: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20083226}. Cytoplasm {ECO:0000269|PubMed:20083226}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20083226}.
Interaction partners:
- Ribosome production factor 2 homolog
- Probable ribosome biogenesis protein RLP24
- GTP-binding protein 4
- Ribosome biogenesis protein NSA2 homolog
- 60S ribosome subunit biogenesis protein NIP7 homolog
- Pescadillo homolog
- Nucleolar complex protein 2 homolog
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- Probable rRNA-processing protein EBP2
- WD repeat-containing protein 74
Sequence:
MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYTEMDYARAGNKAAFTVSLDPGPLEQFPHSMEPQLRQLGLPTALKRGVVTLLSDYEVCKEGDVLTPEQARVLKLFGYEMAEFKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDDD
Protein: NEP-interacting protein 1 (Q1PF53)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transcription factor PAR2
- 26S proteasome regulatory subunit 4 homolog A
Sequence:
MMIARFVLSILIVAAIVSGSEFSDTRDAKVEKILKKLNKPALKSIKSPDGDIIDCVHMNNHPIYDHPLFKNYTIQMKPSSYPKGKNNESSDKEKQSVVTQLWTVNGKCPKNSIPIRRTRRKEILRTEYMQRYDKKNPNIINHPKASTSNSIHEYAQIQAKGKFHGAHADINVWKPFVQTPKEFSLAQMWVMAGPFSEVNSVEAGWQVYQDRYGDDNPRYFIFWTADGYHSGCYNLDCQGFVPVSQKFALGAAVSNVSTFDGQQYHISTTIWKDPNSGNWWLKFGDEFVGYWPSILFNHLKDGATEIQWGGEIINFKDGALHTTTRMGSGHFAESGYQKASYFKDVEIIDERDIHSSPKEGYSYMTQESCYNIRSGYAKVWGVYFYYGGPGRNLNCK
Protein: LIMR family protein At3g08930 (Q9SR93)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Beta-galactosidase 4
- ABC transporter D family member 2, chloroplastic
- ABC transporter D family member 1
- Glycine-rich protein 3 short isoform
Sequence:
MGDFNLALVIVAIVVCVIVFISSIYLLVNYQHPDDANQAYFPKFVVVFGLSIAMISILMLPADVANRHACRHAIYNGACNLTLPMKDLWLAIYIVDAILVFFVIPFAMFFYEGDQDKTLGKRIKSALIWVVTTAVVCALVLGILYGVIGKVDFSVRHLASATSTFPTSWQFSNTQPCIGNTARQCSAFTANPTSEKTWTMRTTFPEYVVALATIVGSVLFTIFGGVGIACLPLGLITAFIRRPKAVITRSQYIKEATELGKKARELKKAADGLHQEERSGAKGRKWRKNVKAVEKELLQLEEDVNLLEEMYPQGEQAETAWAFTVLGYLAKFILGIVGLIVSIAWVAHIIIYLLVDPPLSPFLNEVFIKLDDVWGLLGTAAFAFFCFYLLLAVIAGAMMLGLKLVFITIHPMKWGATLMNSFLFNVGLILLCSISVIQFCATAFGYYAQATAAQEIFGHTLQSLRGIKYLYKYNVFQIGFVILAGLTFLYYIAFGWRRKKTSGRFQLSS
Protein: DNA-directed RNA polymerase subunit Rpo10 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit N) (B8YB63)
Organism: Saccharolobus shibatae (strain ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12) (Sulfolobus shibatae)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00250, ECO:0000269|PubMed:22848102}.
Interaction partners:
Sequence:
MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVIHYTRPI
Protein: Inositol-1,4,5-trisphosphate 5-phosphatase (Q9FFU3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Type I inositol polyphosphate 5-phosphatase 12
- Inositol-pentakisphosphate 2-kinase
- ABC transporter-like protein
Sequence:
MASSSSSSSSSSLSSILSIVVVLILIVSTAESVKSPFHPRDLLPHLPRQVSWPILNSLYGAADLLPTFIGTASSGNDSVDWKGACFFENTAWLEFHNKSGSEFGGGTLHIKADKAHSWTCMDLYVFATPYRVTWTWYFISRQHTVEFPEWDGKAEYEYVKNKGVSIFLMHAGMLGTLQALWDVFPLFSNTGWGESSNLAFLEKHMGANFEPRPEPWVTNVTTDQIQSGDLLAISKIRGRWGGFETLEKWVSGAYAGHSAVALRDSEGKLWVGESGNENDKGEDVIAILPWEEWWAFEQTKDDSNPQIALLPLHPDVRAKFDVAAAWKYARSMEGKPYGYHNLIFSWIDTVSENYPPPLDAHLVASFMTVWSQMQPEYAANMWNEALNKRLGTEGLDLSDVLVEVEKRGSSFDKLLAVPELDDWIYSDGKSTSCIAFILEMYKEAGLFGPLASSIQVTEFTIKDAYMLNFFENNASRLPTWCNDNDSVKLPYCQILGKYRMELPGYNTMEPYSHMNEQCPTLPPKYNRPDNC