wanglab/gogpt-training-data huggingface dataset:
Protein: Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform (Testicular secretory protein Li 1) (cDNA, FLJ96799, Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA) (A8K7B7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (Q386G0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Syntaxin 5
- Golgi SNARE protein-like
- Golgi reassembly stacking protein
- Vesicle tethering protein Uso1/P115-like head domain-containing protein
Sequence:
MFGGLDSSGDEGEGLANQGPSGNRNTRQVASRGMRSMFAEDDMQSRQGVTSLRYEDKGTDKAVARSVMGSGGATGQQSNASSPLQTAVQAVVVAYKGEEVIGSCVVAACVPRTSATAPPLIAIIDRDKRPQCRVRMDENLQLIQSEGEPQYASLFDPSFGGHWSLMFKGRRECTEFVASVLTALNSSRLQDSGVTPPIVEWGSGASPYEELGAAARTVTRGDTVTISFTSWLLQRVPGTSFFSLGKVIEEVPPEAPREVSVGSGTMMIGVENALTGMREGGFSRLVFVTPRLTKVNRGLGNPEVQPSDTVVTHITCHEILRAVGRNKASRPAHQVGTVEADNVNSAFDNTTAALGAPAVISDRRECPPGSVETGAAQTGSSDVNSLMQVLLLQTLQQQQQQKQSVSAPVAEGGQLSSIERSVERLHLQIATLYEKVDRLGIDEKIEKNNAAIERIVKKVVGKVPMGEVDLEDAVKDRDGLLATIERLKGRLEEETSNYHRALEAMSRHKDEVLQLQKDLQLQQETHGARVQQLEEDRRLRLVEAHVQQQQAVERVGEEKFREGYEAGVRATEQKHKEQRALDPAATDGCTTQEWKDRLFASEQRAVQLETALQQAEGRHIAERRQLQEHVDALTRMTTMLQERAEAKASAVEILDGQQTAEQQSAFLRRTMNSVYVNLETQLRAMGSDTVSVLDVLHLLSSVTAAEVSAFSDDASKEALLQWNPAVSANSDPVELHSTHVANYLQDASEMRAGGTEGTSDTLGSVGYAHISGIDQPPVVHDETGQLGVPPPPEGESLFAFNSDVDGFPEPPNLLIDAEDGNDAAGGGIDNVRNLGEIFLEGAPRVTDGDD
Protein: E3 SUMO-protein ligase EGR2 (EC 2.3.2.-) (AT591) (E3 SUMO-protein transferase ERG2) (Early growth response protein 2) (EGR-2) (Zinc finger protein Krox-20) (P11161)
Organism: Homo sapiens (Human)
Function: Sequence-specific DNA-binding transcription factor. Plays a role in hindbrain segmentation by regulating the expression of a subset of homeobox containing genes and in Schwann cell myelination by regulating the expression of genes involved in the formation and maintenance of myelin (By similarity). Binds to two EGR2-consensus sites EGR2A (5'-CTGTAGGAG-3') and EGR2B (5'-ATGTAGGTG-3') in the HOXB3 enhancer and promotes HOXB3 transcriptional activation (By similarity). Binds to specific DNA sites located in the promoter region of HOXA4, HOXB2 and ERBB2 (By similarity). Regulates hindbrain segmentation by controlling the expression of Hox genes, such as HOXA4, HOXB3 and HOXB2, and thereby specifying odd and even rhombomeres (By similarity). Promotes the expression of HOXB3 in the rhombomere r5 in the hindbrain (By similarity). Regulates myelination in the peripheral nervous system after birth, possibly by regulating the expression of myelin proteins, such as MPZ, and by promoting the differentiation of Schwann cells (By similarity). Involved in the development of the jaw openener musculature, probably by playing a role in its innervation through trigeminal motor neurons (By similarity). May play a role in adipogenesis, possibly by regulating the expression of CEBPB (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P08152}.
Interaction partners:
- NGFI-A-binding protein 2
- Early growth response protein 3
- Transcription factor SOX-10
- Early growth response protein 1
- NGFI-A-binding protein 1
- Periaxin
- Protein c-Fos
- Protein FosB
- Histone acetyltransferase p300
- CREB-binding protein
Sequence:
MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP
Protein: Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial (PDHE1-A) (EC 1.2.4.1) (Protein IAA-CONJUGATE-RESISTANT 4) (Q8H1Y0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:14671022}.
Interaction partners:
- Pyruvate dehydrogenase E1 component subunit beta-3, chloroplastic
- Pyruvate dehydrogenase E1 component subunit beta-2, chloroplastic
- Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial
- Dihydrolipoyl dehydrogenase 1, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component 3 of pyruvate dehydrogenase complex, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component 4 of pyruvate dehydrogenase complex, chloroplastic
- Dihydrolipoyllysine-residue acetyltransferase component 5 of pyruvate dehydrogenase complex, chloroplastic
- Dihydrolipoyl dehydrogenase 2, mitochondrial
Sequence:
MALSRLSSRSNTFLKPAITALPSSIRRHVSTDSSPITIETAVPFTSHLCESPSRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEALAVGMEAAITKKDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYKKDASFYGGHGIVGAQIPLGCGLAFAQKYNKDEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMGTATWRSAKSPAYFKRGDYVPGLKVDGMDALAVKQACKFAKEHALKNGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQVRDPIERVRKLLLTHDIATEKELKDMEKEIRKEVDDAVAQAKESPIPDASELFTNMYVKDCGVESFGADRKELKVTLP
Protein: PhzG (EC 1.4.-.-) (Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5)) (O69755)
Organism: Pseudomonas aeruginosa
Interaction partners:
Sequence:
MGVNANISESLTGTIEAPFPEFEAPPANPMEVLRNWLERARRYGVREPRALALATVDGQGRPSTRIVVIAELGERGVVFATHADSQKGRELAQNPWASGVLYWRESSQQIILNGRAERLPDERADAQWLSRPYQTHPMSIASRQSETLADIHALRAEARRLAETDGPLPRPPGYCLFELCLESVEFWGNGTERLHERLRYDRDEGGWKHRYLQP
Protein: Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A) (Q15834)
Organism: Homo sapiens (Human)
Function: Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:17014843, ECO:0000269|PubMed:17873903}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17014843}. Cell junction, adherens junction {ECO:0000269|PubMed:25009281}.
Interaction partners:
Sequence:
MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPAPELALPPCGPRDLGDGSSSTGSVGSPDQLPLACSPDD
Protein: DNA repair protein RAD50 (AtRAD50) (EC 3.6.-.-) (Q9SL02)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Implicated in double-strand breaks (DSBs) repair by non-homologous end joining (NHEJ). Involved in telomere maintenance. Involved in telomerase action on chromosome ends. Required during meiosis for both male and female gametophytic development, for pairing and synapsis of homologous chromosomes during the early stages of meiotic recombination, especially during the pachytene stage of the first division.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q92878}. Chromosome {ECO:0000250|UniProtKB:Q92878}. Note=Localizes to DNA double-strand breaks (DSBs). {ECO:0000250|UniProtKB:Q92878}.
Interaction partners:
- Double-strand break repair protein MRE11
- Nibrin homolog
- Chlorophyll a-b binding protein 3, chloroplastic
- Serine/threonine-protein kinase ATM
- Serine/threonine-protein kinase ATR
- ATP-dependent DNA helicase 2 subunit KU70
- DNA ligase 6
- Dentin sialophosphoprotein-like protein
- Protein BREAST CANCER SUSCEPTIBILITY 1 homolog
- ATP-dependent DNA helicase 2 subunit KU80
Sequence:
MSTVDKMLIKGIRSFDPENKNVVTFFRPLTLIVGANGAGKTTIIECLKVSCTGELPPNARSGHSFIHDPKVAGETETKAQIKLRFKTAAGKDVVCIRSFQLTQKASKMEYKAIESVLQTINPHTGEKVCLSYRCADMDREIPALMGVSKAILENVIFVHQDESNWPLQDPSTLKKKFDDIFSATRYTKALEVIKKLHKDQAQEIKTFKLKLENLQTLKDAAYKLRESIAQDQERTESSKVQMLELETSVQKVDAEVHNKEMMLKDLRKLQDQVSIKTAERSTLFKEQQRQYAALPEENEDTIEELKEWKSKFEERLALLGTKIRKMEREMVDTETTISSLHNAKTNYMLEISKLQTEAEAHMLLKNERDSTIQNIFFHYNLGNVPSTPFSTEVVLNLTNRIKSRLGELEMDLLDKKKSNETALSTAWDCYMDANDRWKSIEAQKRAKDEIKMGISKRIEEKEIERDSFEFEISTVDVKQTDEREKQVQVELERKTKQNSERGFESKIEQKQHEIYSLEHKIKTLNRERDVMAGDAEDRVKLSLKKTEQENLKKKHKKIIDECKDRIRGVLKGRLPPEKDMKREIVQALRSIEREYDDLSLKSREAEKEVNMLQMKIQEVNNSLFKHNKDTESRKRYIESKLQALKQESVTIDAYPKLLESAKDKRDDRKREYNMANGMRQMFEPFEKRARQEHSCPCCERSFTADEEASFIKKQRVKASSTGEHLKALAVESSNADSVFQQLDKLRAVFEEYSKLTTEIIPLAEKTLQEHTEELGQKSEALDDVLGISAQIKADKDSIEALVQPLENADRIFQEIVSYQKQIEDLEYKLDFRGLGVKTMEEIQSELSSLQSSKDKLHGELEKLRDDQIYMERDISCLQARWHAVREEKAKAANLLRDVTKAEEDLERLAEEKSQLDLDVKYLTEALGPLSKEKEQLLSDYNDMKIRRNQEYEELAEKKRNYQQEVEALLKASYKINEYHDLKKGERLDDIQEKQRLSDSQLQSCEARKNELAGELNRNKDLMRNQDQLRRNIEDNLNYRTTKAKVEELTREIESLEEQILNIGGIAAVEAEIVKILRERERLLSELNRCRGTVSVYESSISKNRVELKQAQYKDIDKRHFDQLIQLKTTEMANKDLDRYYNALDKALMRFHTMKMEEINKIIRELWQQTYRGQDMDYIRIHSDSEGAGTRSYSYKVLMQTGDTELEMRGRCSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDGPNSESLAGALLRIMEDRKGQENFQLIVITHDERFAQMIGQRQHAEKYYRVAKDDMQHSIIEAQEIFD
Protein: Complement factor H-related protein C (Q0KHD3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGFCSMLLLSNILLTAWLSTAKGEVKSCEFPQFKYGRLYYEEILRPNFPVSIGNKYSYKCDNGFSPPSGIFWDYLRCTVQGWEPEVPCVRKCVFHYVENGQSAYWEKIYVQGQSLKVQCYNGYSLQNGQDTMTCTENGWSPPPKCIRIKTCSVSDIEIENGFFSESFRTYALNRETSYRCKQGYVTNTGETSGSITCLQNGWSPQPSCIKSCERPVFENSVTKNNSTWFKLNDKLDYECLIGYENEYKHTKGSITCTYYGWSDTPSCYEIECSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHRVGPDSVQCYHFGWSPSFPTCKAGQVASCAQPPEIPNGEINGAKRVEYSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCVEEERTCGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCLSGKWTQLPKCVATDQLEKCRVLKSTDIEAIKPKRKEFQHNSTMYYKCRDKQEYEHSICINGKWNPEPNCIRKISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMCKDGRWQSLPHCIEKIPCSQPPTIEHGSIKLPRTSEKRRKSIEFSSHEHGTTFSYVCDDGFRIPEENGVACYMGKWSTPPRCVGLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDILPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGRWIGKPVCKDSRGKCGPPPPIDNGDITSLSLPEYEPFSSVDYQCQKYYLLKGKKTITCRNGKWSEPPTCLHACIIPENIMEARKIILKWRHTKNIYSHSGEDIEFECKYGYHKARGSPPFRTKCISGTINYPTCE
Protein: H-2 class II histocompatibility antigen, I-E alpha chain (P23150)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
RSRALILGVLALTTMLSLCGGEDDIEADHVAFYGISVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFGQLTSFDPQGGLQEIATGKYNLEILIKDSNFTPAANEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFIIQGLRSGGTSRHPGPL
Protein: Interferon-induced protein with tetratricopeptide repeats 1B (Interferon-induced protein with tetratricopeptide repeats 1-like protein) (Q5T764)
Organism: Homo sapiens (Human)
Interaction partners:
- Interferon-induced, double-stranded RNA-activated protein kinase
- Eukaryotic translation initiation factor 3 subunit E
- Eukaryotic translation initiation factor 2-alpha kinase 3
- Antiviral innate immune response effector IFIT1
- Eukaryotic translation initiation factor 2-alpha kinase 1
- eIF-2-alpha kinase GCN2
- Interferon-induced GTP-binding protein Mx1
Sequence:
MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAADLNPIF
Protein: RUNX1 partner transcriptional co-repressor 1 (A0A0A0MSU1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MCHPDKAFTSDKLQCVFNEYKAAVWVPPRPRPLSRAPLPEAGGENLHLKISRVRKRNLPFVVWGEEEASTPGLDAISHHLCYPDRTHRDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR
Protein: LD39986p (Rab10) (O15971)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Rab GDP dissociation inhibitor
- Eps15 homology domain containing protein-binding protein 1, isoform F
- Guanine nucleotide exchange factor MSS4 homolog
- Exocyst complex component 6
- Rab proteins geranylgeranyltransferase component A
- DENN domain-containing protein Crag
- Vacuolar protein sorting-associated protein 35
- FI01544p
- CG2885
Sequence:
MAKKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRNQEKAPGYSKCCA
Protein: Structural polyprotein (PP) [Cleaved into: Precursor of VP2 (Pre-VP2); Capsid protein VP2; Structural peptide 1 (p1) (pep46); Structural peptide 2 (p2) (pep7a); Structural peptide 3 (p3) (pep7b); Structural peptide 4 (p4) (pep11); Protease VP4 (EC 3.4.21.-) (Non-structural protein VP4) (NS); Capsid protein VP3] (P61825)
Organism: Avian infectious bursal disease virus (IBDV) (Gumboro disease virus)
Function: Capsid protein VP2 self assembles to form an icosahedral capsid with a T=13 symmetry, about 70 nm in diameter, and consisting of 260 VP2 trimers. The capsid encapsulates the genomic dsRNA. VP2 is also involved in attachment and entry into the host cell by interacting with host ITGA4/ITGB1 (By similarity).
Subcellular location: [Capsid protein VP2]: Virion {ECO:0000305}. Host cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Capsid protein VP3]: Virion {ECO:0000305}. Host cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Structural peptide 1]: Virion {ECO:0000305}. Host cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Structural peptide 2]: Virion {ECO:0000305}. Host cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Structural peptide 3]: Virion {ECO:0000305}. Host cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Structural peptide 4]: Virion {ECO:0000305}. Host cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSSQYQPGGVTITLFSANIDAITSLSVGGELVFQTSVHGLVLGATIYLIGFDGTAVITRAVAANNGLTTGTDNLLPFNLVIPTNEITQPITSIKLEIVTSKSGGQAGDQMSWSARGSLAVTIHGGNYPGALRPVTLVAYERVATGSVVTVAGVSNFELIPNPELAKNLVTEYGRFDPGAMNYTKLILSERDRLGIKTVWPTREYTDFREYFMEVADLNSPLKIAGAFGFKDIIRAIRRIAVPVVSTLFPPAAPLAHAIGEGVDYLLGDEAQAASGTARAASGKARAASGRIRQLTLAADKGYEVVANLFQVPQNPVVDGILASPGVLRGAHNLDCVLREGATLFPVVITTVEDAMTPKALNSKMFAVIEGVREDLQPPSQRGSFIRTLSGHRVYGYAPDGVLPLETGRDYTVVPIDDVWDDSIMLSKDPIPPIVGNSGNLAIAYMDVFRPKVPIHVAMTGALNACGEIEKVSFRSTKLATAHRLGLKLAGPGAFDVNTGPNWATFIKRFPHNPRDWDRLPYLNLPYLPPNAGRQYHLAMAASEFKETPELESAVRAMEAAANVDPLFQSALSVFMWLEENGIVTDMANFALSDPNAHRMRNFLANAPQAGSKSQRAKYGTAGYGVEARGPTPEEAQREKDTRISKKMETMGIYFATPEWVALNGHRGPSPGQLKYWQNTREIPDPNEDYLDYVHAEKSRLASEEQILRAATSIYGAPGQAEPPQAFIDEVAKVYEINHGRGPNQEQMKDLLLTAMEMKHRNPRRALPKPKPKPNAPTQRPPGRLGRWIRTVSDEDLE
Protein: Prokineticin-2 (PK2) (Protein Bv8 homolog) (Q9HC23)
Organism: Homo sapiens (Human)
Function: May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
Subcellular location: Secreted.
Interaction partners:
- Prokineticin receptor 2
- Prokineticin receptor 1
- Anosmin-1
- KiSS-1 receptor
- Progonadoliberin-1
- Chromodomain-helicase-DNA-binding protein 7
- NMDA receptor synaptonuclear signaling and neuronal migration factor
- Metastasis-suppressor KiSS-1
- Neuromedin-K receptor
- Tachykinin-3
Sequence:
MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
Protein: LOC397764 protein (Musashi RNA binding protein 1 L homeolog) (Q91808)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
METEAPQPGLSPPDSAHDPCKMFIGGLSWQTTQEGLREYFSHFGDVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFEGEDIVEKVCDIHFHEINNKMVECKKAQPKEVMSPTGSVRGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPGAPVLPELTAIPLTAYGPVAAAAAAVVRGGFLGTSSPGPMAELYGAANQESAVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH
Protein: Pre-mRNA processing factor 4 (PRP4)-like domain-containing protein (Q38CE4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- U5 small nuclear ribonucleoprotein component, putative
- H/ACA ribonucleoprotein complex subunit 2
- Small nuclear ribonucleoprotein E
- Nop domain-containing protein
- Trans-splicing factor, putative
- Small nuclear ribonucleoprotein Sm D2
- U6 snRNA-associated Sm-like protein LSm8p
- Sm protein G
- Small nuclear ribonucleoprotein SmD1
Sequence:
MELIDPVVPYGDREVQEALRLLEEPIIVFGETMSERRQRLRKHMVEKGYGSLDAVRGIQHYSGFTAAAAATPRVGRMISGAVEAGGKLSDAPSELVKKRVALLPVTLERAERRIAKLKEAFVAPTAVRAAHHSMVDRLRGLRLTKSVRNVKVVRQRDGPSTSESASISEFFCMPFTCCAAVPALDHIAVTGAVNGVVTMWSASTCRALGSGSTCETGWGPVRHLAAHPIQPLFFSTTMFDSRIAMWRISTQPLDDTSNAGESGSSVAGANGGTGAVADTNLFLKRVALSSSKHTAGINRIAVDPTGVWLASASDDTTVRLWDINNDTPLLPLVSHNGYEDVCGILDVRFHPDSSLLATADKAGRVVAWDLRSGAVSFTAAGKHGGHLQACTCLSWSLCGFRFATGGADNNVHVWDARYLCRGAAGAPCILAGHDDVVTSVEFCRNPSFPAVPAALVSTSLDGTVRLWDMNATGASVQVLRGPSPVRGQCWPAEGGQTGETLFTVAHSKYWSLWSCVADGESCEVTRRETEDTVVSEVVTLLRDDVVTSGFREEEGDGDDEEEEEDEMMALRKHNKTATGESCLAPNNGDECAHESTDDDEDEMQLLKRK
Protein: Magnesium transporter MRS2-3 (Magnesium Transporter 4) (AtMGT4) (Q9LJN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Magnesium transporter that may mediate the influx of magnesium.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Heavy metal-associated isoprenylated plant protein 28
- CASP-like protein 4B1
Sequence:
MRGARPDEFNFSTNPSTPNTGQPTPTYPAGVGGGGGGRKKGVGVRTWLVLNSSGQSEPKEEGKHSIMRRTGLPARDLRILDPLLSYPSTVLGRERAIVINLEHIKAIITAQEVLLLNSKDPSVSPFIDELQRRILCHHHATKPQEEQNSGGEPHTRVDPAQGEAGTEQSSGDQGSEAKKDAKQSLENQDGSKVLPFEFVALEACLEAASSSLEHEALRLELEAHPALDKLTSKISTLNLERVRQIKSRLVAITGRVQKVRDELEHLLDDDEDMAEMYLTEKLAQKLEDSSNSSMNESDTFEVDLPQGDEDDRLPPEFASEANRDGRYLQANDAHELLMSTQSALSRNSRGTHTSSTRSAMTNKLDVEELEMLLEAYFVQIDGILNKLSTLREYVDDTEDYINIMLDDKQNHLLQMGVMLTTATLVMSAFIAVAGVFGMNITIELFTDNKHGPSRFIWTVIGGSIGSICLYVGAIGWCKYKRLLE
Protein: Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5) (Q9D783)
Organism: Mus musculus (Mouse)
Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex. Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25940086}. Cytoplasm, myofibril, sarcomere, A band {ECO:0000269|PubMed:24960163}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000269|PubMed:24960163}.
Interaction partners:
- Kelch-like protein 2
- Kelch-like ECH-associated protein 1
- Leiomodin-3
- Kelch-like protein 41
- Kelch repeat and BTB domain-containing protein 13
- Cullin-3
- Nebulin
- Kelch-like protein 13
- Kelch-like protein 9
- Kelch-like protein 42
Sequence:
MTLGLEQAEEQRLYQQTLLQDGLKDMLDHGKFLDCVVRVGEREFPCHRLVLAACSPYFRARFLAEPDSAGEVRLEEVSPDVVSQVLHYLYTSEIALDEASVQDLFAAAHRFQIPSIFTICVSFLQKRLCLANCLAVFRLGLLLDCARLAVAARDFICARFPLVARDNDFLGLSADELIAIISSDGLNVEKEEAVFEAVMRWASSGDAEAQAERQRALPTVFESVRCRLLPRAFLETRVERHPLVRSQPELLRKVQMVKDAHEGRLTTLRKKKKEKGEQTARAKEANQGTEDTKAEDDEERVLPGILNDTLRFGMFLQDLIFMISEEGAVAYDPAANECYCASLSTQIPKNHVSLVTKENQVFVAGGLFYNEDNKEDPMSAYFLQFDHLDSEWLGMPPLPSPRCLFGLGEALNAIYVVGGRELKDSEDSLDSVLCYDRLSFKWGESDPLPYAVYGHTVLSHMDLVYVIGGKGKDRKCLNKMCVYDPKKFEWKELAPMQTARSLFGATVHDGRIFVAAGVTDTGLTSSSEVYSIADNKWTSFEAFPQERSSLSLVSLAGTLYALGGFATLETESGELVPTELNDIWRYNEDEKKWEGVLREIAYAAGATFLPVRLNVVRLTKM
Protein: Potassium voltage-gated channel subfamily A member 3 (MK3) (Voltage-gated potassium channel subunit Kv1.3) (P16390)
Organism: Mus musculus (Mouse)
Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25644777}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Voltage-gated potassium channel subunit beta-2
- Sedoheptulokinase
- Ubiquitin-like protein FUBI
- Potassium voltage-gated channel subfamily A member 1
- Intermediate conductance calcium-activated potassium channel protein 4
- Potassium voltage-gated channel subfamily A member 2
- Voltage-gated potassium channel subunit beta-1
- Voltage-gated potassium channel subunit beta-3
- Calcium-activated potassium channel subunit alpha-1
- Large ribosomal subunit protein uL14
Sequence:
MTVVPGDHLLEPEAAGGGGGDPPQGGCGSGGGGGGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
Protein: aldehyde oxygenase (deformylating) (EC 4.1.99.5) (Q67WK8)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
- Os03g0805400 protein
- 3-dehydrosphinganine reductase
- Alkaline phytoceramidase family protein, expressed
- sphingosine kinase
- Os07g0563000 protein
- Sphingolipid delta
- Neutral ceramidase
- Very-long-chain aldehyde decarbonylase GL1-9
- Os09g0338500 protein
- aldehyde oxygenase
Sequence:
MAFAVSDELLGTFVPIAVYWLYSGLYIVLDAMGMDDYRLHPKGEEATKNVVSKWTVVKGVLVQQSFQIAVSLLLFTIIGDESGTVRKQPPALVIALQFIIAMFVMDTWQYFMHRYMHVNKFLYKHVHSKHHTLVVPYAFGALYNHPLEGLILDTIGGALSFLIAGMTPKTAIFFFSFATIKTVDDHCGLWLPGNILHVFFSNNSAYHDIHHQLYGNKYNFSQPFFVMWDKILGTYMPYTLENRKGGGFEARPIKLNVAEQSKTD