wanglab/gogpt-training-data huggingface dataset:
Protein: Tumor-supressor protein (O76931)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLPLSMASAEAKQLQRNISLSMSPANGGVISPSTANCNGVASASGGNPNPNSLLTLAPRKEELRFLPLAPMGGNKTCNITISNVQPMKSKLKSVNIVPNSIKSAGAGATVGSADAPLFQLVPSPSNPSQPLVAILAPNRKTTLLGGGASNGQPVVIRSGTPLHKNSLTVETSNKPIQPGGSAAAAAVGGGTGGAPLTLVGKTVVPPKIQAATPVQIPSTGPGAQVSLLANPLKPRAPLILSKVAVDKLRLKFSQVKSNPNALVLGKANHVKKLLTSPNPSGEDKTRSTQNNNKQNTSASQLKPVVAPKTAMPIATEVPTADNNKMSLIKSKPVAIKAVPLPSQEAPIVPAVAPVVTSPEKVDVKPTAKPSIKTAPKPTPKPLEMPVNGPAKEKKATAKEQKQKTMDKPPVVKEIAQHTPCGPKELPKLKRSKSFVSNHPTSPVANNERRHSVAIMAKEVDVIEQPSAAIETITIEDDDESEEEQQKPEIKKTPKQNQKPEKKEAPKKKQIPMPILPAGITISTTSTAKKKAVRKNSSVTTISSSSSDSSSYSDVEVVPTKKTEKELSLLPGISIIKAESLPLSREDFERSLRCDEQVPQTPPKSSSSSSSGSHASEMSPPPKLADPKPSSPSAKNAKKANDHDANPSPSSKTNDFKKSMMQNLNMLKWRGQQPANLQNSTVRFELNEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSACVHPLLYLCQRCNFHGPAADFLAPHFCSVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAPDLPQKRQTNYKPHKSLSAIQEQLQQRQKDKPRKPFRWSEYLKSKGKDVAAPIHLFLNPFPISPNCFEIGMKLEAIDPENCSLFCVCSIVEVRGYRLKLSFDGYSSMYDFWVNADSQDIFPPGWCDETARVLQAPKDYNSERFSWSRYLVKTGGKAAPRALFGHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKICVATVTDILDERIRVHFDGWDDCYDLWVHITSPYIHPCGWHEGRQQLIVPPDYQKSAFIWDDYISEVGGMAASKELFTPRQPMEYQERMKLEVVDQRNPCLIRPATVVTRKGYRVQLHLDCWPTEYYFWLEDDSPDLHPIGWCEATSHELETPPGYLQPKSVMPCDVEGCRGFGNAKRFNLNVHALRECCPYAPENWRQWRSKTVKPPRVAPENIRRGWAKKTKRACSEAKQAIKEDSQQEIVYPKVAEVVQAKRKTSPCEEKVVKKQKQMQKEEDAEQVPDERSLAIARSFVKDYGPQFLPNYRLWQLNSAFKLDDVRTNPLHWTSWDVCEYIERALDSTDIAKVIFEQDIDGRALLMLGRKELDTYLKLKVGPAVKLYSLILNLRIAVVCKFDSKNIELEINTAGPIQREMDTPVSAIKQLPEQSQTNGYKTDHDQELSESGDDDDDEDVMLDSDDFLSVKPSCLVIDEDADGDGDCESDGDVAMVPMEVRTPLRTSS
Protein: Fatty acid binding protein, isoform A (RH46282p) (RH70437p) (Q8INK2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MCSLPHHSSFGVGLVTRKMGNSLSPTVEVTLEGDTYTLTTTSTFKTSAISFKLGVEFDEETLDGRNVKSIITLDGNKLTQEQKGDKPTTIVREFTDNELITTLTIGNVKCVRVYKAV
Protein: Aldehyde dehydrogenase family 3 member F1 (EC 1.2.1.3) (Q70E96)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal
- Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial
- Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial
- Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial
- Aldehyde dehydrogenase family 7 member B4
- Polyamine oxidase 3
- Polyamine oxidase 1
- Probable polyamine oxidase 4
- Polyamine oxidase 2
- Aldehyde dehydrogenase family 2 member B4, mitochondrial
Sequence:
MEAMKETVEESLREMRETFASGRTRSLKWRKAQIGAIYEMVKDNEDKICNALFQDLGKHSTEAFRDELGVVLRTATVAINCLDKWAVPKHSKLPLLFYPAKGKVISEPYGTVLVLSSWNFPISLSLDPLIGAIAAGNTVLLKSSELSPNASAFLAKTIPAYLDTKAIKVIEGGPDVATILLQHQWDKIFFTGSPKIGRIIMAAAAQHLTPVTLELGGKCPTIVDHHTISKNIKSVVKRIAGGKWGSCNGQACISVDYVLIEKSFAPTLIDMLKPTIKSFFGENPKESGCLSRIANKHHVQRLSRLLSDPRVQASIVYGGSIDEDKLYVEPTILLDPPLDSEIMNEEIFGPILPIITVRDIQESIGIINTKPKPLAIYAFTNDENLKTRILSETSSGSVTFNDVMIQYMCDALPFGGVGESGIGRYHGKYSFDCFSHEKAIMEGSLGMDLEARYPPWNNFKLTFIRLAFREAYFKLILLMLGLKR
Protein: DnaJ homolog subfamily C member 22 (Q9VX95)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGTTQTVSPVAGKDKTNDTSKGSPSKAKSNGHAQGKTKSKEMNALPPQKSVVIAYLCWLFGGIFGLHHLYLHRDRHAFIWWCTLGGYMGIGWMGELFLIPEYVRDANEDPKFVKMFVAKLQAYPKPPYSSKRFVGQVMIGHLFGQVCSMAIPETLVGGWDLSFLHWTIPLFVSLGVWLVGNIGREQGVWWHCLVAAYLAYPARYLIYDETYSLLLTGLVAALTFDGLSKQWRRTPPRRGSPGERTFKLTTAVIIYCAFWGSFLYFNGTISDEDGGEVPIHEAIHNFLASAWWTDLKQALLDTYNYAQHHGWYETWKEVFESMDVDGERNSYKVLGVSATASQAEITAAYRKLSKEYHPDKVKDEGLRAQAHQRFIEIQQAYSVLSKIKSNRRRKNKQYQEEEAIVL
Protein: Fas (tnfrsf6)-associated via death domain (Protein FADD) (A0A0R4IXF0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Caspase 22, apoptosis-related cysteine peptidase
- Caspase 8, apoptosis-related cysteine peptidase
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- Receptor
- Tumor necrosis factor receptor superfamily member 6
- Receptor-interacting serine-threonine kinase 3.
- Tumor necrosis factor receptor superfamily, member 1a.
- Tumor necrosis factor ligand superfamily member 6
- Myeloid differentiation primary response protein MyD88
- TNF receptor-associated factor
Sequence:
MDKRGFRAMLLEISDKLTDDNVAKLKFLCTDVGIGKKKLEKIDTGIELFECLIERTAIGPENTELLRTLLDKVGQTVLIEKIDDYDRQTSRSPAGGLDAKERERINTATEVVVEQLGKKWPSVGRKLGLQQTQLEGIQEKHSRDLEEQVRELIRQWMRIKKENARVEDLIQALRDCKQNLTADLVERKLREL
Protein: Glutamate decarboxylase 2 (GAD 2) (EC 4.1.1.15) (Q42472)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the conversion of glutamate to 4-aminobutanoate (GABA). The calmodulin-binding is calcium-dependent and it is proposed to directly or indirectly form a calcium regulated control of GABA biosynthesis.
Interaction partners:
- Gamma-aminobutyrate transaminase POP2, mitochondrial
- Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1, mitochondrial
- Glutamate dehydrogenase 2
- Glutamate dehydrogenase 1
- Probable glutamate dehydrogenase 3
- glutamate dehydrogenase
- Pantoate--beta-alanine ligase
- Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial
- Asparagine synthetase 1
- Glutamate synthase 1, chloroplastic
Sequence:
MVLTKTATNDESVCTMFGSRYVRTTLPKYEIGENSIPKDAAYQIIKDELMLDGNPRLNLASFVTTWMEPECDKLIMDSINKNYVDMDEYPVTTELQNRCVNIIARLFNAPLEESETAVGVGTVGSSEAIMLAGLAFKRKWQNKRKAEGKPYDKPNIVTGANVQVCWEKFARYFEVELKEVNLSEGYYVMDPDKAAEMVDENTICVAAILGSTLNGEFEDVKRLNDLLVKKNEETGWNTPIHVDAASGGFIAPFIYPELEWDFRLPLVKSINVSGHKYGLVYAGIGWVVWRAAEDLPEELIFHINYLGADQPTFTLNFSKGSSQIIAQYYQLIRLGFEGYKNVMENCIENMVVLKEGIEKTERFNIVSKDQGVPVVAFSLKDHSFHNEFEISEMLRRFGWIVPAYTMPADAQHITVLRVVIREDFSRTLAERLVADISKVLHELDTLPSKISKKMGIEGIAENVKEKKMEKEILMEVIVGWRKFVKERKKMNGVC
Protein: Uncharacterized protein (G5EB58)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MKIFHRCCAALTLLANALPALSLPGANSLTIRKDSNKYVTAHFMVGIVENYTVDDWKHDMELAKETGIDAFALNCASIDSYTDKQLAYAYEAAEEVDFKVFISFDFAYWSNGDTARITSIMQTYADHPGQFQYNGAALVSTFVGDSFDWGPVKRAVDHPIFAVPNLQDPNWAGHATTSIDGAFSWYAWPTDGGNSIIKGPMTTIWDDRFRNNLKDKVYMAPVSPWFSTHFNTKNWVFICEDLPHLRWQQMLEMQPELIEIISWNDYGESHYIGPYSEAHSDDGSAQWTKDFPHDAWRIIAKPYIAAYKAGEREPTVESDQLVYWYRPTPKAVTCSKDPLGPPNGINLLEDSVFVTTLLTEPATLTVGSGSLEFSVDVDAGIVTNSFPMGVGSQAFSVTRDGEEILGGDGGLDVQDRCDYYNFNVYVGSFSA
Protein: Thymidylate synthase (TS) (TSase) (EC 2.1.1.-) (Q58167)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: Is able to catalyze the biosynthesis of dTMP using dUMP, tetrahydrofolate and formaldehyde in vitro, i.e. a reaction equivalent to that catalyzed by bacterial thymidylate synthases (EC 2.1.1.45). However, M.jannaschii like most methanogenic Archaea lacks folates, thus the physiological cosubstrate is unknown but is likely one of the non-methylated methanopterin biosynthetic intermediates.
Interaction partners:
- Uncharacterized protein MJ0758
- Uncharacterized protein MJ0759
- Uncharacterized protein MJ0760
Sequence:
MVLNINSFYKNCRGEFMRAVFIYHKNNQRMEKFYKNLLNEPDFCRICDDCYNCRGNWTFKNNVKNIVIEEVYEEFVDNPYDYLPELPEGDICIAQLHEDLLYELPLLLKEKGYKALIVPSETPHDLSLALRRDLKRVCSNYNIEFENPKPFCSLEKKEGNEYINKFIDYFKIGKPELEIEVENGLIKDVKVKISAPCGETYYIAKRLKGKAIDDLKEEIANAHHNYPCLASMEMDKELGDTILHKAGYIAFEVVEKALKK
Protein: GIT ArfGAP 1 (J3QRU8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSLRSQSDLDDQHDYDSVASDEDTDQEPLRSTGATRSNRARSMDSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQLRQPPGPVPTPPLPSERAEHTPMAPGGSTHRRDRQAFSMYEPGSALKPFGGPPGDELTTRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSRHTSKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKLVA
Protein: Acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase family protein (Q72B12)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Acetylornithine aminotransferase
- Diaminopimelate epimerase
- LL-diaminopimelate aminotransferase
- tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Sequence:
MSSQLLSRLDNLRDRVIELQRNMTALPALGPESGGEGERAKADYLLSVLRDMGMPLIEEIDAPDPRVPCGHRPNIAARIPGRTGRTLWVIGHMDVVPPGEAALWDTDPWQLKVDGDIIFGRGVEDNQQGIVTGLLVAQELLASGTVPDMGFGLLLVADEETGNNYGMAHVATARPDLFGDDDLVIVPDFGTEDGAMIEIAEKSMLWLKVQVAGKQCHASTPDEGINSLVAASAMILRVHELDARFDAVDPLFNPPASTFVPTKKEANVPNVNTVPGNDVFYIDCRVLPCYLLTDVRQAVREIADDIERAYGVTVTLSDVQAEQAAPATSSDSDVVHRLTRAIRAEYGVEARPMGVGGGTVGAILRKRGLPVAVWSTLVPNPHTPNEASRISRTIGDAKVVARMLFDA
Protein: Autotransporter (Q79GN7)
Organism: Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Interaction partners:
- Tracheal colonization factor
- Pertussis toxin subunit 1
- RNA polymerase sigma factor
- DUF3120 domain-containing protein
- UPF0276 protein BP2925
- Autotransporter subtilisin-like protease
- Pertussis toxin subunit 2
- BrkA autotransporter
- Outer membrane porin protein OmpQ
- Outer protein D
Sequence:
MAGQARGWYGAGGRHPIHFQISAGAALMLGLLDVAGAAAVTAAQRIDGGAAFLGDVAIATTKASEHGINVTGRTAEVRVTGGTIRTSGNQAQGLRVGTENAPDNTALGASVFLQNLIIETSGTGALGVSVHEPQGGGGTRLSMSGTTVRTRGDDSFALQLSGPASATLNDVALETAGQQAPAVVLWQGAQLNAQGLVVQVNGAGVSAIHAQDAGSFTLSGSDITARGLEVAGIYVQEGMQGTLTGTRVTTQGDTAPALQVEDAGTHVSMNGGALSTSGANSPAAWLLAGGSAQFRDTVLRTVGEASHGVDVAAHSEVELAHAQVRADGQGAHGLVVTRSSAMVRAGSLVESTGDGAAALLESGHLTVDGSVVHGHGAAGLEVDGESNVSLLNGARLSSDQPTAIRLIDPRSVLNLDIKDRAQLLGDIAPEAQQPDGSPEQARVRVALADGGTWAGRTDGAVHTVRLLDRGVWTVTGDSRVAEVKLEGGTLAFAPPAQPKGAFKTLVATQGISGTGTIVMNAHLPSGTADVLVAPQGFGDRQVLVVNNTDDGTESGATKVPLIEDEQGHTAFTLGNMGGRVDAGARQYELTASEAQADKARTWQLTPTNELSTTATAAVNAMAIAASQRIWQAEMDVLLRHMSGLHSIGSPGGFWARGLSQRQRLDTGYGPWQKQTVSGIELGLDRRVAGGATTAWSVGMLAGYSETRRDGGAYRAGHVHSAHVGAYVSYLNDSGSYVDGVVKYNRFRHGFDIRTTDLKRVDAKHRSHGLGALLRGGRRIDIDGGWYVEPQASVAWFHAGGSRYEASNGLRVRADGAHSWVLRAGAEAGRQMRLANGNIVEPYARLGWAQELGADNAVYTNGIRHVTRSRGGFAEARVGVGALLGKRHALYADYEYAKGARFEAPWTLQLGYRYSW
Protein: PDZ domain-containing protein GIPC2 (Q8TF65)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Unconventional myosin-VI
- SH3 domain-binding protein 4
Sequence:
MPLKLRGKKKAKSKETAGLVEGEPTGAGGGSLSASRAPARRLVFHAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAKRRGL
Protein: Protein UL131A (F5HET4)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. Contributes to the formation of the complex between UL128, UL130 and gH-gL.
Subcellular location: Virion membrane {ECO:0000269|PubMed:16894182, ECO:0000269|PubMed:23804643}. Note=Found as a pentameric complex at the surface of virion envelope. {ECO:0000269|PubMed:23804643}.
Interaction partners:
Sequence:
MRLCRVWLSVCLCAVVLGQCQRETAEKNDYYRVPHYWDACSRALPDQTRYKYVEQLVDLTLNYHYDASHGLDNFDVLKRINVTEVSLLISDFRRQNRRGGTNKRTTFNAAGSLAPHARSLEFSVRLFAN
Protein: High mobility group protein, putative (Q57XJ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA-directed RNA polymerase
- RuvB-like helicase
- Histone H2A
- General transcription factor IIH subunit 4
- rRNA adenine N
- rRNA adenine N
- DNA repair and transcription factor protein, putative
- Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein
- DNA 5'-3' helicase
- TFIIH basal transcription factor complex helicase/translocase XPB subunit
Sequence:
MATELKKGPLPTDIEETVITIMREEGVRYITAKILRMRLESKYQMEFGPHKAAIDDIVARAMQRPEFKKQLELALKEKDASKSSGGKGSKRARSAGAEAPSKTKKEMTEKPKKPADYPKPAVSSYLLFVADQREELKAKNPGMQNTAILQTLGKMWSDASDDVKEHYRKKAEEDKARFRREVDEYKRQGGKEYGRGGKIKKDSNAPKRAMTSFMFFSSDFRSKHSDLSIVEMSKAAGAAWKELGPEERKVYEEMAEKDKERYKREMAALPK
Protein: Proline/betaine transporter (Proline porter II) (PPII) (P0C0L7)
Organism: Escherichia coli (strain K12)
Function: Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:10026245, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium/proline symporter
- RNA chaperone ProQ
- High-affinity choline transport protein
- Glycine betaine/proline betaine-binding periplasmic protein
- Small-conductance mechanosensitive channel
Sequence:
MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAAFNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGATPAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE
Protein: Tubulin tyrosine ligase-like 3 (A8B1U6)
Organism: Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)
Interaction partners:
Sequence:
MNNDITALDGIKHSYIVCKYSFGPGNNAALVEQVLKSRPWWTSTDDENDFNLRWQQLTPAPMRFASMCSTMRRTVFNHLPGNGTLHSKVSLYQILLRKLGKPALDFLPVTYILTVPHERDKFRRHFAALASVIDRYKASQCTENVGAGEPAKKADKDLVVESACAEEQAVRSKSSINVELSSTPYQTNMRNLWIVKPIGLNRGRGIKVVTNPEDAIEHMKGCQERAREEQKTKANKAENLEQQSDDVPTLDKITNITTSMSFIVQKYVEEPFLINGRKFDIRTYALITSDGNAYIYEYGYLRLTSAKYSLDTTDTTVHLTNNAVQKNIHGYNQFEDGNMLHFRDLDVQMSVSDDSLSKTHFTSFIWPVMKRIMAAVLVAFGKAVLGAHACDGCFELFGFDFMIDCKSNGYRPILIEINSNPCLALSSVVSWELLPKMLDDLMDLTIDKLFPPPRAYRDKLWKAYSEARSGKRPSTDLLFTGRPDAKVPSTELRWNGLKADQPVVTRLNMFTQVMQRWKPCGLEIEKSAQEDEGRTLLKILNDPAIAVYQPACGFIHSCIAQTNGSSSKSSSSGNRRASNTNNKGGKCTSSEREVGRSETSIRRRHPPKIMALSDRSLSNIPKRKSAIHETKNVRSQESSATSSTGKATLTSDTGSDIATEY
Protein: DNA damage-inducible protein F (P28303)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- LexA repressor
- Multidrug resistance protein MdtK
Sequence:
MPPGVAVCFSSLFIRLVCMAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARTLVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTAWRGNFRRLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLTSLTQIQQLADRYLIWQVILPVVGVWCYLLDGMFIGATRATEMRNSMAVAAAGFALTLLTLPWLGNHALWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT
Protein: MADs-box protein, GDEF1 (Q9ZS28)
Organism: Gerbera hybrida (Daisy)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRGKIEIKKIENNTNRQVTYSKRRNGIFKKAHELTVLCDAKVSLIMFSNTGKFHEYISPSTTTKKMYDQYQSTVGFDLWSSHYERMKETMKKLKDTNNKLRREIRQRVLGEDFDGLDMNDLTSLEQHMQDSLTLVRERKYHVIKTQTDTCRKRVRNLEQRNGNLRLDYETIHQLDKKYDTGENEGDYESVVAYSNGVSNLYAFCVHPNNIPHGAGYELHDHQHTN
Protein: Neuronal growth regulator 1 (A0A4W4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
- Potassium voltage-gated channel, subfamily H
- Seizure-related 6 homolog b
- G protein-coupled receptor, class C, group 5, member Ba
- N-terminal Xaa-Pro-Lys N-methyltransferase 2
Sequence:
MDIMIAVQDACVSGQWLTAIILSLCCFLPSCLPAGQTVDYTTSSESVVSRQGDTALLRCYLLDGISKGAWLNRSSIIYAGNDKWSGDPRVSIVSNVGDKHEYSLQIQKVDVTDEGVYTCSIQSERNLHPKLIQLIVKVPPKIYDISSDITVNEGSNVSLICAASGKPEPKISWRHISPSARKYESGEYLNITGISRDQAGDYECGAENDIASPDTKTVRVTVNFPPAIHEMKSHGVRPGQVALLRCEAAAVPSPVFEWYKGEKRINMGQGIVINNLSSRSVLTVKNMTQDRYGNYTCVAVNRLGTANASVPLNPSNPAMYGSTGGAEVLLACWYLILALSSLVTVY
Protein: Protein YghO (Q46840)
Organism: Escherichia coli (strain K12)
Interaction partners:
Sequence:
MMNPVLWLQMTNMISYQGLVRTFLNKNDLKAFIAFPSSLYPDDPNWIPPLFIERNEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGKDTGHFGMIDAIDDPQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYAAHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQILREIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNINEAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEALRDPFARRKIDALEMSWILETNTGMNNMLERIGAEPYKRYRLYEKQI
Protein: NOT2/NOT3/NOT5 C-terminal domain-containing protein (Q10923)
Organism: Caenorhabditis elegans
Interaction partners:
- CCR4-NOT transcription complex subunit let-711
- Not3 domain-containing protein
- CCR4-NOT transcription complex subunit 9
- CCR4-NOT transcription complex subunit 7
- CCR4-NOT transcription complex subunit 11
- CCR4-NOT transcription complex subunit 4
- poly
- RING-type E3 ubiquitin transferase
- Protein PAT1 homolog 1
- Endonuclease/exonuclease/phosphatase domain-containing protein
Sequence:
MNSVGGVATERRLPQTQQFLSHSNFHSNATIIDESQFPSLGAKGTSSLGGGGFSPIPTTSGGVLNVAQSSPSRDLYGAQRPNYANLMRSDPSLTNPEFQIQNEDFPALPGVGSGQTQRSMLGDQLANMLADDHQVDFAGPLGDCDPSRLSGISRNSQEGPMHGIITHPDGEVTNIPASMLDDQFGMAGLVTYLRTVDNPSIVSLALGYDLTTLGLNLNLSERKLYMNFGGPWADSPIRAHELDVKVPEEYMTHNHIRDKLPPLRLNKVSEDVLFYLFYNCPNEIYQVAAACELYAREWRFHKSEQVWLTRSQYGGVKEQTGNYEKGHYNVFDQMQWRKIPKELKLEYKELEDRPKMPQSVSGQPTPYKYFFQGPQFPSGPETGLMLQMHNLTLGTGGGGGGQITPPAPAGLNGVMGGGGVGAAGIGGINVQPGAVPSAARATPN
Protein: Vasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor) (P47901)
Organism: Homo sapiens (Human)
Function: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.
Subcellular location: Cell membrane {ECO:0000269|PubMed:33713620}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Vasopressin-neurophysin 2-copeptin
- Guanine nucleotide-binding protein G
- Vasopressin V1a receptor
- Vasopressin V2 receptor
- Guanine nucleotide-binding protein subunit alpha-12
- Guanine nucleotide-binding protein subunit alpha-13
- Guanine nucleotide-binding protein subunit alpha-11
- Oxytocin-neurophysin 1
- Corticotropin-releasing factor receptor 1
- Pro-opiomelanocortin
Sequence:
MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAETIIF
Protein: UDP-glucuronosyltransferase 1A8 (UGT1A8) (EC 2.4.1.17) (A3) (UDP-glucuronosyltransferase 1-8) (UDPGT 1-8) (UGT1*8) (UGT1-08) (UGT1.8) (Q64634)
Organism: Rattus norvegicus (Rat)
Function: UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens and estrogens. Produces dihydrotestosterone (DHT) diglucuronide from the DHT after two subsequent glucoronidation steps. Also catalyzes of the glucuronidation the isoflavones genistein, daidzein, glycitein, formononetin, biochanin A and prunetin, which are phytoestrogens with anticancer and cardiovascular properties. Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist caderastan, a drug which can inhibit the effect of angiotensin II.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9HAW9}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAPSGCPPSLPLCVCLFLASGFAQAGRLLVVPMDGSHWFTMQMIVEKLSHRGHEVVVVIPEVSWHMGKSLNFTVKLLLVLNTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFTDTMTFKERVWNHLSYMKERAFCPYFFKTAVEIASEVLQTPVTMRDLFSPVSIWMFRTDFVLEFPRPMMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
Protein: NAD-dependent epimerase/dehydratase family protein (Q86HU8)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Probable lanosterol 14-alpha demethylase
- Small ribosomal subunit protein eS30
- Squalene synthase
- Cycloartenol synthase
- Protein erg2 homolog
Sequence:
MSKPNVLILGGVGFIGRNLVQYLVEQKCCNKIRVADKVLPATAFLGAKHLEAFADPSVEYMQGNLASAASITKCFTLEGGKFNIVFNLAGETKYGQTDAVYNEKVYDVSVKCATEAAKVGVDKFIEVSTAQIYSSNKKPSKEGDKTDPWTLIASHKLKAEKALKEINGLNLIIVRPSVVYGPGDILGISPRIITGAVYKHTNEKMKFLWDGDLKYNTVHVNDVCKALWFLSQNGKVGDVYNLSDKGDTDAQTISKILEKIFAIKTGFVGNMLSNVASLKMKDVCEEVNDKHLKPWSDLCKDKGISNTPLTPYIDQELLSNTHLSVDGTAIEGLGFKYDNPEITEALVREQIDYFINQNLFPKF
Protein: Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase) (Q9BWD1)
Organism: Homo sapiens (Human)
Function: Involved in the biosynthetic pathway of cholesterol.
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:7911016}.
Interaction partners:
- Hydroxymethylglutaryl-CoA synthase, cytoplasmic
- Hydroxymethylglutaryl-CoA synthase, mitochondrial
- Enoyl-CoA delta isomerase 2
- Peroxisomal bifunctional enzyme
- Trifunctional enzyme subunit alpha, mitochondrial
- Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
- Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial
- Citrate synthase, mitochondrial
- Peroxisomal acyl-coenzyme A oxidase 1
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
Sequence:
MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
Protein: Calmodulin-like protein 5 (Protein MULTICOPY SUPPRESSORS OF SNF4 DEFICIENCY IN YEAST 3) (O22845)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potential calcium sensor.
Interaction partners:
- Uncharacterized GPI-anchored protein At4g28100
- SAC3 family protein C
- Calcium-binding protein KRP1
- Dynamin-related protein 4C
- At5g54130
- Putative RING-H2 finger protein ATL12
- xyloglucan O-acetyltransferase 2
- DNA damage-repair/toleration protein DRT100
- Aspartyl protease AED3
Sequence:
MVRIFLLYNILNSFLLSLVPKKLRTLFPLSWFDKTLHKNSPPSPSTMLPSPSSSSAPTKRIDPSELKRVFQMFDKNGDGRITKEELNDSLENLGIYIPDKDLTQMIHKIDANGDGCVDIDEFESLYSSIVDEHHNDGETEEEDMKDAFNVFDQDGDGFITVEELKSVMASLGLKQGKTLDGCKKMIMQVDADGDGRVNYKEFLQMMKGGGFSSSN