wanglab/gogpt-training-data huggingface dataset:
Protein: Glutathione S-transferase (EC 2.5.1.18) (GST class-pi) (A0A060WT29)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU368105}. Mitochondrion {ECO:0000256|RuleBase:RU368105}. Nucleus {ECO:0000256|RuleBase:RU368105}.
Interaction partners:
- Peroxiredoxin-6
- Glutathione synthetase
- Cytochrome P450 1A
- Glutathione S-transferase omega
- Peroxiredoxin-6
- glutathione transferase
- glutathione transferase
- glutathione transferase
- glutathione transferase
- Uncharacterized protein
Sequence:
MHDNISNIPCPPGLHYLNILNLLSGTPRLLQHKMGPYTITYFGVRGRCGAMRIMMADQGQEWKEIVVDFADWMKGDLKATCVFGQLPKLEDGGFALYQSNAILRHLGRNHDAYGKDGKEAALIDMMCDGVEDLRLKYVKMIYQEYDTGKDVYIKDLPNHLDKFEAVMAKNKTGFLVGDKPSFADYSLFEVLLNHLVLCSSCLDTFPSLKSFVEKMSARPKIKTFLDSEAYKKLPINGNGKQ
Protein: F-box DNA helicase 1 (EC 5.6.2.4) (DNA 3'-5' helicase 1) (F-box only protein 18) (Q8K2I9)
Organism: Mus musculus (Mouse)
Function: 3'-5' DNA helicase and substrate-recognition component of the SCF(FBH1) E3 ubiquitin ligase complex that plays a key role in response to stalled/damaged replication forks (By similarity). Involved in genome maintenance by acting as an anti-recombinogenic helicase and preventing extensive strand exchange during homologous recombination: promotes RAD51 filament dissolution from stalled forks, thereby inhibiting homologous recombination and preventing excessive recombination. Also promotes cell death and DNA double-strand breakage in response to replication stress: together with MUS81, promotes the endonucleolytic DNA cleavage following prolonged replication stress via its helicase activity, possibly to eliminate cells with excessive replication stress. Plays a major role in remodeling of stalled DNA forks by catalyzing fork regression, in which the fork reverses and the two nascent DNA strands anneal. In addition to the helicase activity, also acts as the substrate-recognition component of the SCF(FBH1) E3 ubiquitin ligase complex, a complex that mediates ubiquitination of RAD51, leading to regulate RAD51 subcellular location (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8NFZ0}. Chromosome {ECO:0000250|UniProtKB:Q8NFZ0}. Note=Accumulates at sites of DNA damage or replication stress. PCNA is required for localization to DNA damage sites. Localizes to the nucleoplasm in absence of DNA damage. {ECO:0000250|UniProtKB:Q8NFZ0}.
Interaction partners:
- Fanconi anemia group M protein homolog
- S-phase kinase-associated protein 1
- DNA repair protein RAD51 homolog 1
- ATP-dependent DNA helicase Q5
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- DNA repair protein XRCC3
- Proliferating cell nuclear antigen
- DNA repair protein RAD52 homolog
- Structure-specific endonuclease subunit MUS81
- E3 ubiquitin-protein ligase RAD18
Sequence:
MRRFKRKHLTVVDCHHLARSHLAVTQPFSQRWTNRDPNHGLYPRPRTKGRNRGRGCQRYISEFFLAGHQHCTNDMAKSNSVGQDSCQDAEGDMILTAESSCTLPQVDNGEARLGSSGSAQPARKRAHCFEEATESGQWDGVTKKTPRHRLFPSCSRLREARQGAEDSLSQCSPVPGEAGRDIEDIGPDPLPDSYYGLLGMLPCQEVPSHICRLPSEVLRHIFAFLPVEDLYWNLSLVCHLWREIINDPLFIPWKKLYHRYLINEEQAVSKVDGILSSHGIEKDSDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLLEAEACMRQQLPDLYAAAGGINVWALVAAMVLLSSCVNDIQHLLFCLRRPSSTVTMPDVTETLYCIAVLLYAMREKGINISNRIHYNIFYCLYLQENSCTQATKVTEEPSVWPGKKTSIQLTHEQQLILNHKMEPLQVVKIMAFAGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAELVFPSNVICKTFHSMAYSHVGRKYQLKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSHGQRVMVEQSEKLNGVLEASRLWDNMRKLGECKEEAYQMTHDGYLKLWQLSKPLLASFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRFGVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGDIKGQVALLSRTNANVFDEAVRVTEGESPARIHLIGGIKSFGLDRIIDIWTLLQPEEERRKRDLIIKDRFIRRWVHKEGFSGFKRYVTAAEDKELEAKIAVVEKYNIRIPELVERIERCHIDDLDFAEYILGTVHKAKGLEFDTVHVLDDFVKVPCARHNLAQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGEYFLQAELTSNVLKTGVVHCCVGQCNNTIPVDTILTMKKLPITYSNRKENKGGYLCHSCAEQRIGPLAFLTASPEQVRAMERTVEDIVLPRQEALLFLVF
Protein: Zinc finger protein 74 (Zinc finger protein 520) (hZNF7) (Q16587)
Organism: Homo sapiens (Human)
Function: May play a role in RNA metabolism.
Subcellular location: Nucleus.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 15
- Transcription intermediary factor 1-beta
- Protein DGCR6L
- Protein DGCR6
- Zinc finger protein 69
- Integral membrane protein DGCR2/IDD
- Protein HIRA
Sequence:
MEIPAPEPEKTALSSQDPALSLKENLEDISGWGLPEARSKESVSFKDVAVDFTQEEWGQLDSPQRALYRDVMLENYQNLLALGPPLHKPDVISHLERGEEPWSMQREVPRGPCPEWELKAVPSQQQGICKEEPAQEPIMERPLGGAQAWGRQAGALQRSQAAPWAPAPAMVWDVPVEEFPLRCPLFAQQRVPEGGPLLDTRKNVQATEGRTKAPARLCAGENASTPSEPEKFPQVRRQRGAGAGEGEFVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTGEKPFFCGECGKAFSCHSSLNVHQRIHTGERPYKCSACEKAFSCSSLLSMHLRVHTGEKPYRCGECGKAFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSDCEKAFNSRSRLTLHQRTHTGEKPFKCADCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKAFSSHAYLIVHRRIHTGEKPFDCSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQNHCLIKHQKIHSGEKSFKCEKCGEMFNWSSHLTEHQRLHSEGKPLAIQFNKHLLSTYYVPGSLLGAGDAGLRDVDPIDALDVAKLLCVVPPRAGRNFSLGSKPRN
Protein: AP-4 complex accessory subunit RUSC2 (Interacting protein of Rab1) (Iporin) (RUN and SH3 domain-containing protein 2) (Q8N2Y8)
Organism: Homo sapiens (Human)
Function: Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:15796781}. Cell membrane {ECO:0000269|PubMed:30905672}. Note=Cytosolic punctate distribution. Also observed in the perinuclear region. Colocalizes with RAB35 at the membrane protrusions of HEK293T cells (PubMed:30905672). {ECO:0000269|PubMed:15796781, ECO:0000269|PubMed:30905672}.
Interaction partners:
- Ras-related protein Rab-35
- Ras-related protein Rab-1B
- Golgin subfamily A member 2
- Ras-related protein Rab-1A
- Diphosphomevalonate decarboxylase
- Squalene synthase
Sequence:
MDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLGQADSLLFSSLHSTPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGVGEPGLGDLYDDSIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTLDTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSDESPRNPGCSGSGDQHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLNSAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYRRKNPLGPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPDFQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWGFLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVSQDLLLSAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAAGGSGRARWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPKESLQEPHSPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTLTPTPSPTPGSSQN
Protein: Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase) (EC 4.1.1.-) (Coenzyme Q biosynthesis protein 4 homolog) (Q382H9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
Subcellular location: Mitochondrion inner membrane {ECO:0000255|HAMAP-Rule:MF_03111}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03111}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03111}.
Interaction partners:
Sequence:
MQSRVVSSAVMFLGGIAGAVKSLPAFVTSSFGAIVDPEDGRGSAAFAEITALTALHHMQRLMMADEMGRSILKERPQVTDETLEFAKTQPEGTFGYRYAAFMKRNNFLPSGRAPILHVSDPTLAYVMLRYRQIHDFVHAYVGLGRTIEEELAVKLFEWQHTGLPVGLMAVLGGMPWLRMDQILNMGMYNEWARANAPRQLHGKRFVSCILNVPWEWYLDKPYEQLVDDVGIVPLDAFLKERKSGGLHDS
Protein: Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 (Protein SEC FOURTEEN HOMOLOGS 3) (AtSFH3) (Q93ZE9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for transport of secretory proteins from the Golgi complex (By similarity). Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- F16L1.9 protein
- AT3g10210/F14P13_19
- Transmembrane protein
- Egg cell-secreted protein 1.3
- At4g35750
- Appr-1-p processing enzyme family protein
- Proline-rich receptor-like protein kinase PERK9
- Leucine-rich repeat
- Small ribosomal subunit protein eS25x
Sequence:
MTDTMSAHMDRHNKLDYDGSEDEKKTKLCSLKKKAINASNKFKHSFTKRTRRNSRVMSVSIVDDIDLEELQAVDAFRQALILDELLPSKHDDHHMMLRFLRARKFDLEKAKQMWTDMIHWRKEFGVDTIMEDFDFKEIDEVLKYYPQGYHGVDKDGRPVYIERLGQVDATKLMQVTTIDRYVKYHVREFEKTFNIKLPACSIAAKKHIDQSTTILDVQGVGLKSFSKAARDLLQRIQKIDSDNYPETLNRMFIINAGSGFRLLWSTVKSFLDPKTTAKIHVLGNKYQSKLLEIIDSNELPEFLGGNCTCADKGGCMRSDKGPWNDPDIFKMVQNGEGKCPRKTLSNIEEKTISVDENTTMKSDSFAKNKFDAENTKFIPMIDKTVNASTWPTNLHKSNYPEPEDLYSAVKPSQRRGGEGYLFGGVMSLVMGLMTVVRLTKNMPRKLTEAAIYGGEVDKAETTMVSNQEYMSMVKRMAELEEKCRSLDNQPAAFSPEKEQILTAALSRVDELELQLAQTKKTLEETMATQHVIMAYIDKKKKKKKFFGF
Protein: HYPERSENSITIVE TO PI STARVATION 4 (F4I9T6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAASPAKFFFGFLIVSIVLWMIFILCSRLFAWMLSRVLGASVVFRVGGWKCLKDVVVKFKKGAIESVSASEIKLSLRQSLVKLGVGFLSRDPKVQVLISDLEVVMRSSTSTTNLQKAKSHKPRTSGRGKWMVVANVARFLSVSVADMVVKTTKVIVEVKELKLDINKDGGTKPNLYVKLNVLPILVHLCESRIISDQSSNVSFECCPASQASSASPDRSAATLFCDELSLSSEFGHDRAVGIVVRNVEVTSGDVILNFDEDSFPKSKQSSASLRSDEVRTSATAASSAKKPHKEHQLVAALAKYSSSFPEKVSFSLPKLDVRCVNREHDLLAENNITGIQLRSVKSKSFEDTGESTRLDVQMELSEIHVFREADSSILEIMKVDVVSFIYIPVQPVLPIRAEVDIKLGGTRCNLFISRLQPWLRLHFLKKKKLVLQEKTHNLEKTKAADMKAIMWTGTVSAPEMTVMLYGTEDIPLYHFCSQSSHVFANNVSSLGTAVHVELGELNLHLADEYQECFREHLFGIEPNSGSLMHIAKVSLDWGRRDRTSSDEVGFRSKLVLSVDVTGMGIYFSFKRVQSLIINALSFKALFKTLSVTGKKMNKTVSVQPSKGSGKGTRLVNINLERCCVNFCDDTGLDNTVIDDPKSVNYGSQGGRVSFSSLADGTPRTASILSTAPEACKRLKYSVSLEISQFSFCLNKDKLSTQMELGRAKSIYQEYLEEHTPCSNVILFDMHNAKLVRRSGGLNEIDVCSLFSATHISLGWEPDVHLSFYELFLRLRSLVYAQRHKEPESGCNKGISSVKDGGPSEKINQSNSVNKQKKKESMFAIDVETLTISAEVGDGVEVKLEAQSIFSENACIGVLLEGLMLAFNGSRVFKTTRMQVSRIPTATNLSDAVPVMTDGPWDWVVQGLDVHICMPYKLQLRAIDDSIEEMLRGLKLISVAKGKHILSGKRESSKPKKSSPKFGRIKFCIRRLTADIEEEPIQGWLDEHYQLVKKEACELAVRLKFLEDLIHKAGQSPKGAETSAVLDERKMFFDGVEIDVEDPVAINKVKEEIHKRSFQSYYQACQGLAPSEGSGACREGFQAGFKPSAARTSLLSVCATDFDLSLTAVHGGDAGLIEVLKKLDPICEENDIPFSRLYGSNVYLNTGSLVVQLRNYTLPLLSGTSGKCEGRIVLAQQATCFQPQISQDVFVGRWRKVKMFRSASGTTPPLKTYSDLRIHFEQGEVSFGVGYEPAFADISYAFTVALRRANLSHRNPDMVQVIKKERSLPWWDDMRNYVHGNITLSFSESKWSVLATTDPYESLDQLQIVSGPIELKQSDGRVFVSAKDFKIKLSSLESLISRHSLKVPVRASGAAFIEAPDFNLEVTMDWDCESGNSLNHYLYAFPAEGKPREKVFDPFRSTSLSLRWNFSLRPEKFHQSPSSTEHPTDVGTVYSSQDKPDSIPLASPTMNLGAHDLAWILKFWGLNYYPPHKLRSFSRWPRFGVPRAARSGNLSLDKVMTEFMLRVDATPSLIKYMPWDSDDPAKGLTFNMAKLKYELCYSRGKQKYTFECKRDALDLVYQGLDLHVPKAFINKDEHPCIPGSVQVLRKSTQDALIDRVPSGKDHKRYEKHRDEGFLLSSDYFTIRRQAPKADPERLLAWQEAGRRNLEMTYVRSEFENGSESDEHIRSDPSDDDGYNVVIADNCQRVFVYGLKLLWTIENRDAVWSFVGGISKAFEPPKPSPSRQYTQRKIHEENQKESCPETHQGEMSRSSASPGRNLPSSPSHSIKIEKSDDIGTVETIESEEEGTRHFMVNVIEPQFNLHSEEANTSHIFKQCAEKNISFRCRKEFEQKKIYYWNLLLLKKYIFELHDDIINQQNYFCYCLCGRVLARSFHSIMRVGVEVIEQALGTGSVKIPECSPEMTWTRMEVSVMLEHVQAHVAPTDVDPGAGLQWLPKIRRNSPKVKRTGALLERVFMPCDMYFRYTRHKGGTPDLKVKPLKELTFNSHNIIATMTSRQFQVMLDVLTNLLFARLPKPRKSSLQCPTEDEDVEEEADEVVPYGVEEVELAKINLEEKERERKLLLDDIRKLSPCSDNMDDTHIEREGELWMISTRRSILVQGLKKELTYAQKSRKAASASLRMALQKAAQLRIMEKEKNKSPSYAMCISLQINKVVWSMLVDGKSFAEAEINDMIYDFDRDYKDIGVARFTTKYFVVRNCLPNAKSDMLLSAWNPPPEWGKKVMLRVDAKQGAPKDAHYPLELFHVEIYPLRIHLTETMYRMMWEYFFPEEEQDSQSRQEVWKISTTAGSKRVKKGLVGHESSGHAIKDVEASRMSSSALSASAAVQSQSNDDSVQKSNVICLRSSTGASAQELRRTSSFDREENVAEPIANELVLQAHSCNVSSSIEQQEDFSKQKVKEIKPVKSGRSSHEEKKAGKSHEEKKSRPRKMMEFHNIKISQVELLVTYEGSRFVVNDLKLLMDTFHRVEFTGTWRRLFSRVKKHIIWGVLKSVTGMQGKKFKDKSHNNRESTDNDLNLSDNDQTGKPDQQQVTWFKRQSDGAGDGFVTSIRGLFNTQRRKAKAFVLRTMRGEAENDFHGDWSDSDVEFSPFARQLTITKAKRLIRRHTKKFRPRSQRGSTSQQRESLPSSPIETTPFESGYSSGSSPYEDFRE
Protein: Probable NOT transcription complex subunit VIP2 (Protein VIRE2 INTERACTING PROTEIN2) (AtVIP2) (Q9FPW4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional regulator required for Agrobacterium-mediated stable genetic transformation by T-DNA integration in host genome, but not for T-DNA transient expression.
Subcellular location: Nucleus {ECO:0000269|PubMed:17496122}.
Interaction partners:
- Transcription regulator
- Transcription regulator NOT2/NOT3/NOT5 family protein
- Cell differentiation, Rcd1-like protein
- Cell differentiation, Rcd1-like protein
- Cell differentiation, Rcd1-like protein
- RNA binding
- RNA binding
- AT5g35440/MOK9_2
- CCR4-NOT transcription complex subunit 11
- Carbon catabolite repressor protein 4 homolog 1
Sequence:
MSNLHSSLNGSASNLPDGSGRSFTASYSGQSGAPSPSFHHTGNLQGLHNIHGNYNVGNMQGTLTSRNSSMNSIPSAGVQQPNGSFSSGRFASNNLPVNLSQLSHGSSHGHSGIPNRGLNVVGNPGFSSNANGVGGSIPGILSTSAGLSNRNSVPGMGISQLLGNSGPRITNSMGNMVGGGNLGRNISSGGLSIPGLSSRLNLAANSGSGLNVQGQNRMMGGVLPQGSQVMSMLGNSYHTGGGPLSQNHVQSVNNMMLSDHPNDSSLFDINNDFPQLTSRPGSAGGTQGHLGSLRKQGLGVPLVQQNQEFSIQNEDFPALPGYKGGNSEYPMDLHQKEQLHDNAMSMMHSQNFSMGRSGGFNLGATYSSHRPQQQPQHTSSTGGLQGLGLRPLSSPNAVSSIGYDQLIQQYQQHQNQSQFPVQQMSSINQFRDSEMKSTQSEADPFCLLGLLDVLNRSNPELTSLALGIDLTTLGLDLNSTGNLYKTFASPWTNEPAKSEVEFTVPNCYYATEPPPLTRASFKRFSYELLFYTFYSMPKDEAQLYAADELYERGWFYHKELRVWFFRVGEPLVRAATYERGTYEYLDPNSFKTVRKEHFVIKYELMEKRPSLLQL
Protein: SLIT1 (D2XV92)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MAVPPGAASTSGGAAGVPAALRAAAWLLAFVALCRGRAAACPPLCACSGTTVDCHGTALRAVPKSIPRGTERLELNGNNITRIHKNDFSGLKQLRVLQLMENQISVVERGAFDDMKELERLRLNRNQLHTLPELLFQHNQALSRLDLSENFIQAIPRKAFRGATDLKNLQLDKNQISCIEDGAFRALRGLEVLTLNNNNITSIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLAQWLRQRPTIGLFTQCAAPAQLRGLNVAEIQKNEFSCSGQADGVHAQLCSLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKITDLPKGVFGGLFALQLLLLNANKINCVRADAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFVCDCNLKWLADFLRANPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPPKCRCEAGVVECSNLKLTKIPERIPQSTAELRLNNNEISILEATGVFKKLPHLKKINLSNNKVSEIEDGAFEGAASVSELHLTVNQLESVRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQISTIAPGAFDTLQSLSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQHPDFLRQIPLQDVAFPDFRCEEGQEETSCIPRPQCPQECTCLDTVVRCSNKHLKALPRGIPKNVTELYLDGNQFTQVPGQLSTFKYLQLVDLSNNRISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFEGLRSLRLLSLHGNDISTLPEGIFADVTSLSHLAIGANPLYCSCNLRWLSSWVKTGYKEPGIARCAGPPDMEGKLLLTTPAKKFECQGPPSLIVQAKCNPCLSSPCRNQGTCHNDPLGSYRCACPIGYKGRDCEVALDGCSQNPCANGGTCQPQDGDRDGFRCLCAAGFEGPSCRTASDPCKEHSCENGGSCVAGATNYTCLCPAHYTGDFCEQPPDFCSAELSPCQHGSTCIPTSQGPRCECAPGYVGTNCSKDFDDCQDHRCQNNARCVDEVNGYSCLCAEGYSGQLCEMPPHAAGQPGLCERAECQNGAACVERGSRALCQCLPGFGGPKCEKLLSVNFVDRDTYLQFTDLQDWPRANITLQVSTAEDNGILLYNGDSDHMAVELYQGHVRVSYDPGTHPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNSGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQLLNGTSFHGCIRNLYINNELQDFTKTRMTPGVVPGCEPCRKLYCLHGICQPTGAQGPVCHCEPGWDGPHCDQPRGGPCQGHKCVHGLCLPLDALSYSCQCHQGYQGALCNQPSTPPDPCRLLSCHHGRCRLTPGGQPVCECHSGYSGTLCDQEPECHGEPVRDYHQVQRGYAICQTTRPVPYVQCRGTCGGDTDTGCCIGLRP
Protein: Zinc finger C2HC domain-containing protein 1B (Q5TFG8)
Organism: Homo sapiens (Human)
Interaction partners:
- Protein FAM163B
Sequence:
MAGAEPFLADGNQELFPCEVCGRRFAADVLERHGPICKKLFNRKRKPFSSLKQRLQGTDIPTVKKTPQSKSPPVRKSNWRQQHEDFINAIRSAKQCMLAIKEGRPLPPPPPPSLNPDYIQRPYCMRRFNESAAERHTNFCKDQSSRRVFNPAQTAAKLASRAQGRAQMGPKKEPTVTSAVGALLQNRVLVATNEVPTKSGLAMDPASGAKLRQGFSKSSKKD
Protein: Succinate dehydrogenase subunit 3-1, mitochondrial (Q6ZH92)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Succinate dehydrogenase iron-sulfur subunit 2, mitochondrial
- Succinate dehydrogenase subunit 3-2
- Succinate dehydrogenase iron-sulfur subunit 1, mitochondrial
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase subunit 6
- Succinate dehydrogenase subunit 4
- Succinate dehydrogenase subunit 7
- Succinate dehydrogenase subunit 5
- Succinate dehydrogenase subunit 8B
- Succinate dehydrogenase subunit 8A
Sequence:
MEKYHSNSRFAPFRDAPFALRGALGSSGSSFSSIDSLRRSSTLEQARGYTSRPLGAVRPKMLPSGCRPLHTSHPLSAPVANRPLSPHLPLKKPQLSATFSISHRIFGAALGAAIISIPLATKFSLMFDV
Protein: Pentatricopeptide repeat-containing protein At3g53700, chloroplastic (Protein MATERNAL EFFECT EMBRYO ARREST 40) (Q9LFF1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in female gametophyte development.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- RNA-binding
- AT3G20230 protein
- Small ribosomal subunit protein cS23y
- AT-hook motif nuclear-localized protein 18
- RNA polymerase sigma factor sigB
- Pentatricopeptide repeat-containing protein At2g17033
- RNA-binding protein CP33, chloroplastic
- E3 ubiquitin-protein ligase RFI2
- Proteinaceous RNase P 1, chloroplastic/mitochondrial
Sequence:
MAFSSCLKFYPFSISQAVTLTHHSFSLNLTPPSSTISFASPHSAALSSTDVKLLDSLRSQPDDSAALRLFNLASKKPNFSPEPALYEEILLRLGRSGSFDDMKKILEDMKSSRCEMGTSTFLILIESYAQFELQDEILSVVDWMIDEFGLKPDTHFYNRMLNLLVDGNSLKLVEISHAKMSVWGIKPDVSTFNVLIKALCRAHQLRPAILMLEDMPSYGLVPDEKTFTTVMQGYIEEGDLDGALRIREQMVEFGCSWSNVSVNVIVHGFCKEGRVEDALNFIQEMSNQDGFFPDQYTFNTLVNGLCKAGHVKHAIEIMDVMLQEGYDPDVYTYNSVISGLCKLGEVKEAVEVLDQMITRDCSPNTVTYNTLISTLCKENQVEEATELARVLTSKGILPDVCTFNSLIQGLCLTRNHRVAMELFEEMRSKGCEPDEFTYNMLIDSLCSKGKLDEALNMLKQMELSGCARSVITYNTLIDGFCKANKTREAEEIFDEMEVHGVSRNSVTYNTLIDGLCKSRRVEDAAQLMDQMIMEGQKPDKYTYNSLLTHFCRGGDIKKAADIVQAMTSNGCEPDIVTYGTLISGLCKAGRVEVASKLLRSIQMKGINLTPHAYNPVIQGLFRKRKTTEAINLFREMLEQNEAPPDAVSYRIVFRGLCNGGGPIREAVDFLVELLEKGFVPEFSSLYMLAEGLLTLSMEETLVKLVNMVMQKARFSEEEVSMVKGLLKIRKFQDALATLGGVLDSRQPRRTYRSR
Protein: Serine/threonine-protein kinase SZE1 (EC 2.7.11.1) (Protein SUPPRESSOR OF ZED1-D1) (Receptor-like cytoplasmic kinase SZE1) (Q8L617)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:30947022}; Lipid-anchor {ECO:0000269|PubMed:30947022}; Cytoplasmic side {ECO:0000269|PubMed:30947022}.
Interaction partners:
Sequence:
MGNCLSASTLPTEPNAPKSVEEGVKVFTVADLKKATNDFGNQMELGESLGYINPKTLSPAKKGVGMAVAVKKIYLANEQAFQDWLVDVEFLRHNSHPSLVKLIGYCYDRDMLFIVSEYFPNGSLGSYISRDSRPKSLPWETRLKISIGAAQCLAFLHSRKQAGLYRRYLTASKILLDSDFNARVSYFGKPKVSLDELVYTIGFSNVAPRYQYPPPEYILSGMSNMAGDVYSFGVILLKMLTGLGKDLTISAKREIKNKKYNIVEMIDPDLKNSYPLEAGRLMCELIKQCLEVDPKMRPTMQEVLDNLNAIAQI
Protein: Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (Q10106)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Probable U3 small nucleolar RNA-associated protein 18
- Probable U3 small nucleolar RNA-associated protein 7
- KRR1 small subunit processome component homolog
- rRNA-processing protein fcf1
- Uncharacterized protein C3B8.09
- U3 small nucleolar RNA-associated protein 20
- Uncharacterized protein C18B11.06
- U3 small nucleolar RNA-associated protein 6
- U3 small nucleolar RNA-associated protein 10
- U3 small nucleolar ribonucleoprotein protein imp4
Sequence:
MSSSFKNAGQRKNHRERAQPFERRKWGLLEKRKDYAQRAQDYKTKQKKLKRLREKALERNPDEFYHEMTHKKTKNGVPLEQREDSTIDMDTIKILKTQDIGWIRHHRNVERAKIDHLEQQMHTVGAHRNKNESRKHTIFVDNVKEAKSFNPAEFFQTTDDLVGRTENRVKKDQIENNELTNQPFSGKLHSKLKEKAATELLLRQKRDKKLAAAEERVELDRLLQGKGGRQKKKVVNGKPVYKWRNERKR
Protein: Tubulin delta chain (Delta-tubulin) (Q9UJT1)
Organism: Homo sapiens (Human)
Function: Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9R1K7}. Cytoplasm {ECO:0000250|UniProtKB:Q9R1K7}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9R1K7}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9R1K7}. Note=Associated with centrioles. Both cytoplasmic and nuclear. In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head. {ECO:0000250|UniProtKB:Q9R1K7}.
Interaction partners:
- Tubulin epsilon chain
- Gamma-tubulin complex component 2
- Gamma-tubulin complex component 6
- Gamma-tubulin complex component 3
Sequence:
MSIVTVQLGQCGNQIGFEVFDALLSDSHSSQGLCSMRENEAYQASCKERFFSEEENGVPIARAVLVDMEPKVINQMLSKAAQSGQWKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMNIIRKEVEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLGSVFQPTYSAESSFHYRRNPLGDLMEHLVPHPEFKMLSVRNIPHMSENSLAYTTFTWAGLLKHLRQMLISNAKMEEGIDRHVWPPLSGLPPLSKMSLNKDLHFNTSIANLVILRGKDVQSADVEGFKDPALYTSWLKPVNAFNVWKTQRAFSKYEKSAVLVSNSQFLVKPLDMIVGKAWNMFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVASYCNL
Protein: Serine O-succinyltransferase (SST) (EC 2.3.1.-) (Q10341)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine. Has also weak serine acetyl transferase activity and homoserine succinyl transferase activity.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glycerophosphocholine phosphodiesterase gde1
- Uncharacterized solute carrier family 35 member C320.08
- Vacuolar transporter chaperone complex subunit 2
- Zinc finger protein grt1
- Uncharacterized RING finger protein C6B12.07c
Sequence:
MLRASSKRLQLSWQVFRRFQSSNPQLSFPCVDQAQERSRQFEQSLQKQQACPNSVDPSASITSPSLSSGPEPVYGKIVSGFKKFYHNKPFLCDHGGILPKFEIAYETWGTLNKDHSNAILLHTGLSASSHAHSHPENTAPGWWEQFIGPGKDVDTNKFFVICTNVLGSCYGSTGPSSVDPGDGKHYATRFPIITVNDMIRAQLLLLDHLKIEKLYASVGSSLGGMQSLTLGALAPHRVGRIASISGGARSHPYSIALRFTQRQILMNDPYWNRGFYYDGVPPHTGMKLAREVATISYRSGPEWEQRFGNRRADPSVSPAFCPDFLIETYLDHAGEKFCLQYDPNSLLYISKAMDMHDMSASHQRSLSENRKKNQHKLDKYLSADVSAEEIIKLNEDTSVLPDVPYQEIANEDRAPEPDPETNLIAGLAPLKDTPVMVMGVESDNLMPVECQRETARCLEKAGNKQVVYHELDANESFYGHDTFLIYRKDLDLVGGKLKKFLELS
Protein: H/ACA ribonucleoprotein complex subunit 2 (H/ACA snoRNP protein NHP2) (Nucleolar protein family A member 2-like protein) (Q9V3U2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit 1
- Nucleolar protein 56
- H/ACA ribonucleoprotein complex subunit 3
- H/ACA ribonucleoprotein complex subunit 4
- rRNA 2'-O-methyltransferase fibrillarin
- Nucleolar protein 58
- Ribosome assembly factor mrt4
- 60S ribosome subunit biogenesis protein NIP7 homolog
- rRNA 2'-O-methyltransferase fibrillarin
- NHP2-like protein 1 homolog
Sequence:
MGKVKVERSEDADESVVASGDVTIKEEESYDDKLIFVNAIAKPMAGKKLAKKCYKLVKKAMKHKTFLRNGLKDVQTRLRKGETGICIFAGDVTPVDIMCHLPAVCEEKGIPYTYTPSRADLGAAMGVKRGTVALLVRQNEEYKDLYDEVKEELSALNIPV