wanglab/gogpt-training-data huggingface dataset:
Protein: E3 ubiquitin-protein ligase (EC 2.3.2.26) (Q3KRP0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MNMAAQLPEVRGLQTDEDESRILRVKIIAGIGLAKKDILGASDPYTRISLYDPVNGEITSLQTKTIKKTLDPKWNEEFFFRVHPRRHRLLLEVFDENRLTRDDFLGQVDVPLHQIPTEHPNNERPYTFKDFLLHPRSHKSRVKGHLRLKMTYLPKNRRCKDDPAEQGENLDPGWEFLEPHELCSPHHPHQLPALPPGWEERQDNLGRTYYVNHESRTTQWHRPTIQDSQRDNEQRQETHSESQRAFLTRRQISEHEENHERRESPESWEIITADESTLYSSLSERSPPPPHSPMEISTFCEEFNRLQATNDRRTSLTPQVTAAAEEVDRPSRWRSILFTHSLLPTSAGLPPGWEEKQDSKGRIYFVNHNSRTTTWTRPLIQLIQPPSESPASPMASGSTSLSQNAAGYALPPDVSPQHTHTHTHTHTPEHPGLMPTGWEVRSAPSGRPFFIDHNTKTTTWDDPRLKVPVQMRRRVSLDPTDLGPLPPGWESECIVMAESSTLITTQKPHNGKTHDYRIQPSLGPAVPYSRDYKQKYEYFRKKLKKPAEIPNRFELSVRRNAVLEDSYRRILSVKRSELLKARLWVEFEGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDAFFIRPFYKMMLQKPITLQDMESVDSEYFNSLRWILENDPTDLDLRFTIDEELFGQTHQHELKPGGADIVVNDTNKKEYIHLVMQWRFVDRIQRQMTAFKEGFYELIPQDLIKIFDENELELLMCGLGDVDVNDWRENTKYKNGYNPNHPAIIWFWKTVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGTREKLPRAHTCFNRLDLPPXESFEELREKLHMAIENAQGFDGVD
Protein: Cysteine-rich perinuclear theca protein 1 (Q8CH20)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton, perinuclear theca {ECO:0000269|PubMed:15286030}. Note=Found in the postacrosomal region of the perinuclear theca. {ECO:0000269|PubMed:15286030}.
Interaction partners:
Sequence:
MAQMAKKVHWSSAAAGAAAAAKISKLEKTTKRFKLIKKRNPSSKLPKRSSHSLLCSLSRSCCCCRCRCCCYCRCCRCCCSRSRRFRSRTTLKFFQITEKGEQSLQRRIRRQLTRSQLELIEPEPTMALEPSEITVAFFSHKNANVSDPEEVPPCLDSDPFPNGDLASS
Protein: KH-type splicing regulatory protein (M0R3J3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
Protein: RNA polymerase I-specific transcription initiation factor RRN5 (Q02983)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- RNA polymerase I-specific transcription initiation factor RRN9
- RNA polymerase I-specific transcription initiation factor RRN10
- Upstream activation factor subunit UAF30
- RNA polymerase I-specific transcription initiation factor RRN7
- RNA polymerase I-specific transcription initiation factor RRN6
- Histone H3
- RNA polymerase I-specific transcription initiation factor RRN11
- Histone H4
- TATA-box-binding protein
- RNA polymerase I-specific transcription initiation factor RRN3
Sequence:
MEHQQLRKYVELYNKEVEEFYNGAASGRPAEFHPSKVHVKSIHEKAGTANAGVEISSVGVDWDSEEKNTFFWCLSRYSIHRVDEWRSLLPRKSAMEILGYYRLLRRASASARSRKAGDDGAPIAYEMSAEWVALETKLSETVMAITEGAAEVADEEGHCEGLIDYESWKRRWVAIYSHSRIAEIRPLPRHALPLSRSATQTLERCVSRYTRTLLWCTALAGMASRSVSARAAESRGHKSLPTVVTRRQVERALCTEARSRDLHVLPRRIVLTLRKWELDYPREGKLFRTKEMAHLFLQSQLSRRDAPPVHQDENQENQENQENQEQDNTASEGESEAERDEIDEADLFRSALHENQLLKWLSK
Protein: Two component transcriptional regulator (K7WA79)
Organism: Anabaena sp. 90
Interaction partners:
- Circadian input-output histidine kinase CikA
- Histidine-containing phosphotransfer domain containing-protein
- Circadian input-output histidine kinase CikA
- Signal transduction sensor and regulator protein
- histidine kinase
- Two-component response regulator heterocyst pattern formation protein PatA
- histidine kinase
- Uncharacterized protein
- histidine kinase
- histidine kinase
Sequence:
MGSVCIEIVEGNPHLRSLLGWHLQQLEYRVHQAASIYQAKEVFISHQPTLVILDADLSDGDGVEFCRWLHRQQQPLILMLSARTNEADIVAGLKAGADDYLSKPFGMQEFLARVEAIIRRNRTPTAPAYLDYGSLQIDLVQRRVRFQGEFIDLTPQEFSLLYVLAQAGGVPLSRSELLRRAWPDAIDNPRTIDTHVLSLRKKVELDPRQPSLIQTIRNVGYRFNMEILNVNIPQTHTKLPKERFTNQLPVLTTQSS
Protein: RING finger protein narya (Q9VWI4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for the formation of DNA double-strand breaks (DSBs) together with nenya and vilya during the meiotic recombination process. Plays a role in DSBs processing into crossovers. Plays a redundant role with nenya in chromosome segregation during female meiosis.
Subcellular location: Chromosome {ECO:0000269|PubMed:30615609}. Note=Localizes to DNA double-strand breaks during female meiosis in both nurse cells and pro-oocytes (PubMed:30615609). During early pachytene, colocalizes with vilya to the central region of the synaptonemal complex (SC) (PubMed:30615609). {ECO:0000269|PubMed:30615609}.
Interaction partners:
- RING finger protein vilya
- IP04788p
Sequence:
MFRVHCNKCFRHRKTDPAVPFHLTQCRHVICGPCLGQSSLEKNCPLCGQVLKAIQINRDMPTSVANYFADPLRFQQIYRKISKFQADQRASDNLGFYRQLQQLEQNKRQLEGFCKMEAQLNQKVVEEKKRIAELRTYIAYHENAQRMTRRRHSAGERFHTPEFKEAWNTSISTSDKSPSDMPSDSSRRSADLDTQSTRRRSFGSDTKGFRL
Protein: MAP kinase-activating death domain protein (Aboc, expulsion defective protein 3) (Regulator of presynaptic activity aex-3) (O02626)
Organism: Caenorhabditis elegans
Function: Guanyl-nucleotide exchange factor that regulates small GTPases (By similarity). Converts GDP-bound inactive form of rab-3 and cab-1 to the GTP-bound active forms. Regulator of presynaptic activity that interacts with rab-3 to regulate synaptic vesicle release. Is also a regulator of the cab-1 synaptic transmission pathway. Probably by converting rab-3 to its GTP-bound active form, plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by activating rab-3 and thus regulating the trafficking of dense-core vesicles, plays a role in AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Regulates anterior body muscle contractions (aBOC) and the expulsion steps during the defecation motor program (DMP). Probably by regulating DMP, required for fatty acid uptake by intestinal cells.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8WXG6}. Cytoplasm {ECO:0000250|UniProtKB:Q8WXG6}.
Interaction partners:
- Ras-related protein Rab-3
- small monomeric GTPase
Sequence:
MNDKEKEICPRLIDFLVVVGKRNRTRGASQSSPDATTDTTVTYPEILRRYPTDDHKDFILPTDVTVFCQPEGCTTTSARLRKNARNDPQFFVFMLTEKDSAKVRYGICLNFYQSFDRRSTPKDEIKKVPDDAHHKKRDSHVSLTSLCFISHHPFVSIFHQVLLLLKRIIDSSNHRAAQRTGLKDVVWAILTGHYNEPIVPEVMKEIKEIETWILMLLSSPVPVPGKTKVQIEVMPMDLSQVFEFALPDHTRFTLIDFPLHIPFEILGIDMALRVLTAAMLEFKIVIQSRNYNAVSMCILSIVALLYPLEYMFPVIPLLPAYMPSAEQLLLAPTPFLIGVPSSFFHHRKIRELPSDVILVDLDTNCLQVPDDLYIPDLPEPDATHLKERLKNAINKMTTMTVDNETSVTDADFGIDIDSVDVACRVAMVQFFNSANVFGNFSEHTRTLRLYPRPVVSLQTDSFLRSRPQCTQLITDLCRTQAVEYFAECCLCPKNETFVRVQAGIESAEQVGDKPKWFSESLMPVHFMVYPNNSTLDSAIRVYNAEIDNDDYEDDSATSTENSNSIDDLVFDENQVTDAGGEVTKPLAEVNYIYKEPMTLELPQSESVVSIDSSLSSGRSSPDSSLSTSAVDSEADFARLADNLALKSNSQGAFSFDHGSDSEYESTPVSQRRKTIHNPGSDASDTPTSRGSIKSGLRMKGLTTLTDSGEKVLGPSLMNAINGYAEKSQSVFSQVINKTAPKAQALKERTMKPLANRIEQSQHIVRSKTQPNPTSQQTANQQSKNQQTVKEFCDQALVGQSVGMFSAPKLKRLMEDESLRELVCSKLNLGLEVKLSEDEYVKEVQLTKGQFKAYVKILKACLEGIEVSFNTPGCCGFASVFHVLEIAHTHYWAMGGGEVITPSSSAPSTMTTPSEHSNDILKESRPKLPASTIDLRTPTKPLGQNVTPTSTNNHEIAQSTRSPALPPPVPPREAPPIPKRNPPPLGAPPKVPEGARAPPPLPPRPKVKTTAVDETPQNLVPNNQPAQPSSPSFLADADEQTKPLLKPAPPTTLPVGKQEPCKVLPTPNEPVRHYIYQELILAVQHQIWQNLQFWENAFVDLVAQEREIVGMDQEPSEMIDRYSALNDSEKKRLELEEDRLLSTLLHNMTAYMIMCGTGQKALQQKVRRLLGKAHIGLVCSKEINKLLDELPSTQGNFIPLKPLGSRLVQKQSFTVCPGQSSDGQMMFMEVCDDAVVLRSITGAATERWWYERLVNITYSPKTKILCLWRRHDDKVHMHKFHTKKCRELYQCMKAAMERAAARGKVNVEGRALGGEFPVHDTETNQGGLLQVRCDGVAVIFAHNQIFIGLSNIKKCNTFGGNVFLLEEFDRKKGEIIQRRYFSQMADQICYAVLCVFSLAAAGHKKEEHSK
Protein: glutamine--fructose-6-phosphate transaminase (isomerizing) (EC 2.6.1.16) (Q19130)
Organism: Caenorhabditis elegans
Interaction partners:
- Glucosamine-6-phosphate deaminase
- N-acetylglucosamine-6-phosphate deacetylase
- Glucose-6-phosphate isomerase
- Glucosamine 6-phosphate N-acetyltransferase
- Trifunctional purine biosynthetic protein adenosine-3
- glutamine synthetase
- Multifunctional protein pyr-1
- glutamine--fructose-6-phosphate transaminase
- glutamine synthetase
- Glutamine synthetase
Sequence:
MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRKAGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVVHNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRYPDFSFRQLVETVIQQLEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQTDGRRFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWEVEYFVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEIMKGSFKTYMQKEIFEQPDSVVNTMRGRVLPSGQVVLGGIKEYLPDIKRCRRLIMVACGTSYHSAIACRQILEELSELPVVVELASDFLDRETPIFRDDVCLFISQSGETADTLLALRYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDIAKQIYKEKSLLIMGRGLNFATCLEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAPIIIADCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAKSVTVE
Protein: Histone H3-like 2 (Male gamete-specific histone H3) (Q9FXI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H4
- Protein TONSOKU
- Chromo domain-containing protein LHP1
- Histone H2B.6
- Lysine-specific demethylase ELF6
- DNA
- Histone acetyltransferase GCN5
- Histone-lysine N-methyltransferase CLF
- Histone-lysine N-methyltransferase ASHH2
- Chromatin structure-remodeling complex protein SYD
Sequence:
MARTKQTARKSTGGKGPRKELATKAARKTRRPYRGGVKRAHRFRPGTVALREIRKYQKSTDLLIRKLPFQRLVREIAQDFKVDLRFQSHAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMSKDIQLARRIRGERA
Protein: DCD domain-containing protein NRP-A (Asparagine-rich protein) (N-rich protein) (N-rich protein A) (Q5JZR1)
Organism: Glycine max (Soybean) (Glycine hispida)
Function: Involved in stress signaling pathway that mediates cell death in response to endoplasmic reticulum (ER) stress and osmotic stress.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18490446}.
Interaction partners:
- Vacuolar-processing enzyme
- NAC domain-containing protein 6
- Legumain prodomain domain-containing protein
- Legumain prodomain domain-containing protein
- Legumain prodomain domain-containing protein
- ER-binding immunoglobulin protein BiP4
- Proteasome subunit alpha type-5
- NAC domain-containing protein
- Proteasome subunit alpha type
- Vacuolar-processing enzyme
Sequence:
MDNNNDFWKFSDQLRLESGLANLSLNDYSIWSNSYSSKRPDQRRNFDVKGSDFNNNNNSSKAFDDDFNDGWKITNSNGPLFSMPHNNNNNTLEVGGFNKGGGIYSNTNTTISSYHPNNLNNNAFGGFNKGIYSNTTSSPYLNNNHHHLDDNNNLNRNNLKGYKTYFKGEDQFHTPKSAKKKNTTNNTNNKKHGDNTNNNDGTKTGAEKKFKTLPPSESLPKNETIGGYIFVCNNDTMAENLQRQLFGLPPRYRDSVRTITPGLPIFLYNYSTHQLHGIFEAASFGGSNIDPTAWEDKKCPGESRFPAQVQVITRKVCEPLEEDSFRPILHHYDGPKFRLELSVPEALSLLDIFANQNSFDDIFKAIPA
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (G5EDV9)
Organism: Caenorhabditis elegans
Interaction partners:
- Acetylcholinesterase 1
- Carboxylic ester hydrolase
- Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 1
- Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 2
- Choline kinase A2
- Choline kinase B2
- Choline kinase B1
- Putative choline kinase B3
- Vesicular acetylcholine transporter unc-17
- Choline O-acetyltransferase
Sequence:
MRAPVIGRHLTYHVFCQFALVTLFIVRRIEPRSIVRGDHVVHTPLGTIRGVGQTFDGAKVSAFLGVPYAKPPIGSRRFKMAEMIDRWSGELEARTLAKTCYLTIDSAFPQFPGAEMWNPPGAISEDCLNMNIWVPEDHDGSVMVWIYGGGFFSGTPSLDLYSGSVFAAKEHTIVVNVNYRLGPFGFLYFGDDSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFRNIIAKSGSIINSWASATPPTMLDLSFRLAKKVNCSSPDMNAIVKCLRSVPAHLVQAEADNISGDIGPPMTFAYVPVSSDANFFQGDVFQKLANKQFKKDVNIIFGSVKDEGTYWLPYYMSLPKYGFAFNHTISAEDPHNRALITRDHYEESMRAFMPYFAGSKLVLNAFMNSYEHVSTSNVPEERYRDGVARFLGDLFFTCSLIDFADLISDNIFGNVYMYYFTYRSSANPWPKWMGVMHGYEIEYAFGQPYWRPHLYDQTHLEDEKRLSSIIMQIWANFANTGRTDSFWPQYNKIERKAIELGETTLQGKHRIISDVHGGFCRMIDEAKAFVKQKNANDCRTTRKSASTEDLTSSSSTTYLFSIIVYLSILISYISL
Protein: ACF7 protein (Q13696)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
ITSPWAPRPSCSSPAWAMSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLPWNLPLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIKQHTILMSDKTFPQNPVELKALYNQYIHFKETEILAKE
Protein: Photosystem II 22 kDa protein 1, chloroplastic (22 kDa protein of photosystem II 1) (Photosystem II subunit 1) (OsPsbS1) (A2WXD9)
Organism: Oryza sativa subsp. indica (Rice)
Function: Involved in high light-mediated energy-dependent nonphotochemical quenching (NPQ, qE) and thermal dissipation (TD) thus regulating energy conversion in photosystem II and protecting from photoinhibition. Seems also to regulate quantum yield of electron transport in fluctuating light conditions (By similarity).
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250|UniProtKB:Q9XF91}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Photosystem II 22 kDa protein 2, chloroplastic
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein, chloroplastic
- Photosystem I reaction center subunit V, chloroplastic
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein
- Glyceraldehyde-3-phosphate dehydrogenase
Sequence:
MAQSMLVSGANGTVAAASTSRLQPVRPTPFSRLVLSQPSSSLGRAVSVKTVALFGRSKTKAAPARKAEPKPKFKTEDGIFGTSGGIGFTKENELFVGRVAMLGFAASILGEAITGKGILAQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGSFVDDQPVTGLDKAVIAPGKGFRSALGLSEGGPLFGFTKANELFVGRLAQLGIAFSIIGEIITGKGALAQLNIETGVPINEIEPLVLFNVVFFFIAAINPGTGKFVSDDDEE
Protein: NAD-specific glutamate dehydrogenase (EC 1.4.1.2) (Q38EX6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nitrilase, putative
- Aspartate aminotransferase
- aspartate transaminase
- Isocitrate dehydrogenase
- Isocitrate dehydrogenase
- Multifunctional fusion protein
- NAD-dependent protein deacylase SIR2rp2
- Alanine aminotransferase, putative
- glutamine synthetase
- Citrate synthase
Sequence:
MMRRASYCAGHAFTSLTVVGSRRFFQGERCEAEIVKLTKERGIFSDASVEASVHQLMSRLSDSPYVRHYTDAEVSAHAHGFLCAKARSALGEPFEHFHESDDSAFYICRKDQASQLRAVRQLTKFVSRERETKQSVSVRCYTAGDSDIAVFTAKIRPFVNPNPEKGETDIGQLASSAFLEERSPEMQERYQDLINRFHESVVPVHTVREVDGEVCFSMIMAADRSYYIATLQTVIQEIPGAVVTRCFSETFSNDTHVYTYFVRGATSQQLSDRASLVPFLPTRPRSLITRLHEDMVFNTEQTVYTDAAVIFAFYFTPQPTSEDYRHLRSLVSKEPNGLSRLNNLRTTLSLEMMSERYILTLISTYPEFMKEIYEDFQVGTTHERRCAIREKITTRFREDQRSEHDLGIFNAFLQFNEVVLKHNFFKQHKVALCFRLDPSFLRSLGYPRVPHGVFLLAGAQWRGFHVRFTDIARGGVRMIISKDTMYRRNKRSVFQENYNLALTQLLKNKDIPEGGSKGTILVSSRYLNTFNQPLCERIFLQYADALLDVVIPGEEGIVDRLKTPEIIFLGPDEHTAGTFPSVGSLFSKKRGYSAWKSFTTGKDASLGGIPHDTYAMTTRSVRTMVRGVYEKLGLDEASQTKFQTGGPDGDLGSNEILLSKEKTLAVLDISASLFDPEGLNKEELKRLATARKQLRDFDKSKLSSKGFLVLTGDKNVTLPDGTHVSDGVSFRDEFHLTKYSAADVFVPCGGRPRSVTLANVGRFLNLSAADNDSLLAGGSIQLKTPKYKIIVEGANLFISQDARLAIERCGIVLIKDASANKGGVTSSSLEVYAGLALSDEEHAQHMCVKDPNNVPEFYKKYVLDIIERIESNARREFEAIWREQQVQEGMPKTLIADSLSEKNVRVRASILSSDMCENKELVRYVLSKYTPKTLLEVVPLETLMERVPLEYQKAICAMWLASEYVYTTGISGNEFDFFTFMTKHMEQAKHIS
Protein: 3-dehydroshikimate dehydratase (DSD) (EC 4.2.1.118) (Q9I6P6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways. Is required for growth on either quinate or shikimate as a sole carbon source.
Interaction partners:
- Homogentisate 1,2-dioxygenase
- Aromatic-amino-acid aminotransferase
- fumarylacetoacetase
- 4-hydroxyphenylpyruvate dioxygenase
- Probable aminotransferase
- Histidinol-phosphate aminotransferase 2
- Histidinol-phosphate aminotransferase 1
- Aspartate aminotransferase
- D-amino acid dehydrogenase 1
- D-amino acid dehydrogenase 2
Sequence:
MQRSIATVSLSGTLPEKLEAIAAAGFDGVEIFENDLLHYDGSPRDVRRLCADLGLEILLFQPFRDFEGCRRERLGRNLERAERKFDLMQELGTDLVLVCSNVAADALGEPALLADDLRQLAERAAVRGLRIGYEALAWGRQVNTWEQAWDLVRRADQANLGLILDSFHTLSLDGDPRGIADLPGEKIFFVQMADAPLLAMDVLEWSRHFRCFPGQGGFDLAGFLAPVVASGYRGPLSLEVFNDGFRAAPTRANAVDGLRSLLYLEEKTREHLQRQTPHVAVDELFAPPPASLCDGIEFLEFAVDETLGARLGQWLQRLGFARAGEHRSKNVSLLRQGDINLVLNAEPYSFAHGFFEAHGPSLCATALCVRDAGQALERARAYGGQPYRGLLGPNEREIPAVRALDGSLLYLVERHTEGRSIYDSDFVTNDADTSGLGLRRVDHVALALPAEGLDSWVLFYKSLFDFGADDEVVLPDPYGLVTSRAVRSPCGSVRLPLNISEDRNTAIARSLSSYRGSGVHHIAFDCADIFAAVAQAKEAGVALLEIPLNYYDDLAARFDFDDEFLSELAYYNVLYDRDAQGGELFHVFTEPFEERFFFEILQRRHGYAGYGAANVPVRLAAMAQARRGVRRVKL
Protein: Myelin protein zero-like 1 like (E7F7T2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Myelin protein P0 precursor
Sequence:
MEIRLPISSHSYVSLCVSAVFIIAGVSDVSAIDVFTTAEVFVENGTTATLSCSFRSKEVVSRLTTVTWSFLAEGESGASTTILYHSDGKSFPGALPQFKARVEWAGDMNKKDASIRVLQMQFKDNGTYSCDVKNPPDITGQSSPTKVRVVMKEALPQTSAAVIVGGVIGAVIGIILISVVTYLIIRRQKPSHDYEGCTSIESVSTQNTRVGKKAESSNDNSRCSSPSAPVQGPVIYAQLDHSGSKNSSSFHKMEPVVYADIRKN
Protein: Carboxymuconolactone decarboxylase-like domain-containing protein (A0A0H2UNJ6)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTVLEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQALRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLAILCNYANNLANTPINPELQPYA
Protein: Alhambra, isoform M (Q8INT1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMMMDTMDTSQSQPMDVAPAVAVAATSGAALVDFTAAMVSMAATAEAESAESNNNHIDMAEYKEHRKNKKKKREKREREGKEHRHHKHRDREHREHRRHRDRDRDKERDREGHHHHPTHHHPNNSQHSTSASSSPSSASTTPSATIEYVGGSASASPSYLGGGATGTGAAVGATTTYPHNLKIRFLLSGQRTELSPPTHQTSATAEVNAPLASSTSASIAVTASATAASAPPATGTTTLGSSISGNAGSTSSGNSSGVSATGGAQSAVGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQASTASSSSAPSLYVSVPLSTANVPGINLPTSSTSSSTTSESHSASSRSSGAQSQHQQQLSNALVGPPMGGSAGAFHGGTTSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISASGFPLPSGNLTATTTESGNLKISYEKQTTRVQQLQEQEAPPARRSRTLDLSTASASSSSPSAVPATTSPLVVLSNQLPLNSVAASSSTGGLKFTYESQTQMDVPMMPVSAIKDSPPSSPGSEIGSAMHSATTAPGSLTGASTAATAQPGNVRKRGRKAKDATIAAAAAAAAAAAALSNSQQDLKDVRILQNGASNTPGNPAGSTPTPPATPASSNAVSSASSIITHTAAHMLGNQINPNSSVAQKLSEQLHMEVQDHSIYTPDSMNSQYAGVPFPGKQRNSTAVPSNATPAQNPLQSMFSGGGMNGNMPIPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLNCLHQLQSENLRLEEHVTSLIARRDHLLAVNARLQIPLSTIASNTKAEAHAAISTTAAPTTTTTTSTTTATSTCTTSVISTIASSGNSSTSTIGLGSSTSALNAATTIAAAVSLATTAINTTIPTMANSRPTVAAASSSGVLDYRGPGATSNSSNSNSSNNTISNSVSNSSSNPTSSSSASVPPASSMSISGMSISNATNLGMRHVSAAHGSNNAGNSNSSVWSLTASSTVNSNSLHHQHSSQQQQQHQAQHQSHPLQQQQQQQQQVQHHLHQSHHTSAAVAAAHMLGVGMSLGAGGGAAGGIGRVPTKARR
Protein: Transcription factor SOX (Q6P2A2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR038098}.
Interaction partners:
Sequence:
MLQRSSSSSALFDGDSSDSGALDLDAHAASPSPGSTASGGEKLNPGWCKTASGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDGDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSSGSKPSEKLSISKPSSKKRSAGKPHKKEPGPADHHSLYKAKAAPVVKQSPEKKKRLYIFSSSSSPSPAAVPASPTLSSSADTSDPLSLYEDASGSGKEDADTRYTGSSMRAPSPTPSAAHSSSSSQFSSSSDEEPDDDALDANTSPGFDSMSLGSIGSSVLDRDFDMHFDSGASHFEFPDYCTPEVSQLISGDWLESTISNLVFTAHVLN
Protein: Double C2-like domain-containing protein beta (Doc2-beta) (P70169)
Organism: Mus musculus (Mouse)
Function: Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.
Subcellular location: Cytoplasm. Cytoplasmic granule. Cell membrane; Peripheral membrane protein. Note=Translocates to the plasma membrane in a calcium-dependent manner.
Interaction partners:
- Rab effector Noc2
- Synaptosomal-associated protein 25
- Protein unc-13 homolog B
- Secretoglobin family 2B member 24
- Syntaxin-4
Sequence:
MTLRRRGEKATISIQEHMAIDVCPGPIRPIKQISDYFPRFPRGLPPTAAPRAPAPPDAPARSPAASASPRSPSDGARDDDEDVDQLFGAYGASPGPSPGPSPARPPAKPPEDEPDVDGYESDDCTALGTLDFSLLYDQENNALHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKAEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKRIERWHTLTNELPGAVLSD
Protein: RING-type domain-containing protein (Q4GYC6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MYSGDRAELQRLRAREAELEEERKALAAMRAELESRIGGRMNEIHEMEEKVKGMWELEDVNAKLREELDELREVHEQQCEKAEEKLRNAMWELTETQRKVQKFAMEVRNRSNSISICIDSKPSASGASGGDGKSSDGKASGSDPSGQQSGFSIEAELCEAWNCVDKLCVACLEARVALEAKQQRRVASAEGRAATKVNAVMELLPALMAELEDARRQTLSEGERMERQAICGSWGDMSARAVENCRLSHERLAAEEGRYRIAFECSEWQERCQICEAAAMSSFRYLAGAQDQLKATRIADDAQQKQHDMELNRLRAQMKEAEDMWNREVNARQRAHECALLEQQKWHDLAMREAQNRLMKEWEAEKESFQQRINALDEERSHHAFSVLSEAQKREEELRKAAVEMREAFEKSIAAALETSSAMLERYEFETRAGLLKLEHAERSMLRDQEREDRESKCTSTQHLNIHRTTIEFSADILNAAADFRLDFPSMMLERTKIVVDNMKVLHDQRLREVRRRYDNEMRVAASVPRELAKKLEQELEETKCSLRQAAATSEHCEDENRRLTEQIRSLQTQFDERPVAQEIRVDVKNSLLTAMHRLIVAEEATECIFSCGLCMQPLKSPLTCVPCGHTFCEECLLKHPRNITSLQAASQMDSNKRAHLKAGSPLDDSMPGNKSRNPVPLIVRYCPDCAPMNCSSAVRVQVLDSLSGNLRYRKGDIGFLRSVMAEVEKS
Protein: Tailup, isoform A (Tailup, isoform C) (Q9VJ37)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Lim3, isoform G
- Chip, isoform B
- Muscle-specific homeobox protein tinman
- Protein decapentaplegic
- Zinc finger protein ush
Sequence:
MVMAEIGGHLAHQLPLHNHNHNQTGLQPSLVMNHHLDLDCHGHDVIKKQRLSHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSSQSSLTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNGMPILPPHPHSHPAQGPPHQHPPPPGGPHNHQNQQPNQQPGGSSLDSGITSHHHPDSTDSYVTYLESDDKSKLALTPSSSSSASAGTSISSPPSGVGAGGGGAVGGGSGVLGLGVVANQSATEQLMQMLQKVTGSASPASHAVL
Protein: Epididymis secretory sperm binding protein (Heterogeneous nuclear ribonucleoprotein A3, isoform CRA_b) (A0A384NL63)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
Protein: Phosphoinositide 3-kinase regulatory subunit 5 (J3KT66)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
GRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVR