wanglab/gogpt-training-data huggingface dataset:
Protein: Nucleoid-associated protein At2g24020, chloroplastic (Suppressor of tic40 protein 2) (O82230)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Participates with ALB4 in thylakoid protein targeting. May function with specific subset of thylakoidal proteins. Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity).
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:28684427}.
Interaction partners:
- ALBINO3-like protein 1, chloroplastic
- Inner membrane protein ALBINO3
- Cell division protein FtsY homolog, chloroplastic
- Signal recognition particle subunit SRP54, chloroplastic
- Signal recognition particle 43 kDa protein, chloroplastic
- Protein TIC 40, chloroplastic
- Mitochondrial inner membrane protein OXA1
Sequence:
MASMAATTNFTKSMLFPFSHVSGNASLNSQRRTWPKQYKSKNGYRSLRVNGLFGGGNKDNNSEDGQSKAGIFGNMQNMYETVKKAQMVVQVEAVRVQKELAAAEFDGYCAGELVKVTLSGNQQPIRTDITEAAMELGSEKLSQLVTEAYKDAHAKSVVAMKERMSDLAQSLGMPPGLSEGMK
Protein: Eukaryotic translation initiation factor 6-2 (AteIF-6;2) (Q9M060)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03132}. Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03132}. Note=Shuttles between cytoplasm and nucleus/nucleolus. {ECO:0000255|HAMAP-Rule:MF_03132}.
Interaction partners:
- 60S ribosomal export protein NMD3
- At1g43860
- Ribosome assembly factor mrt4
- Probable rRNA-processing protein EBP2 homolog
- Cytoplasmic 60S subunit biogenesis factor REI1 homolog 2
- Cytoplasmic 60S subunit biogenesis factor REI1 homolog 1
- Transducin/WD40 repeat-like superfamily protein
- Probable ribosome biogenesis protein RLP24
- Ribosome biogenesis protein BOP1 homolog
- 60S ribosome subunit biogenesis protein NIP7 homolog
Sequence:
MATRLQFENNCEVGVFSKLTNAYCLVAIGGSENFYSAFESELADVIPIVKTSIGGTRIIGRLCAGNKNGLLVPHTTTDQELQHLRNSLPDQVVVQRIDERLSALGNCIACNDYVALAHTDLDKETEEIIADVLGVEVFRQTIAGNILVGSYCALSNKGGMVHPHTSVEDLEELSTLLQVPLVAGTVNRGSEVIAAGMTVNDWTSFCGSDTTATELSVIDSIFKLREAQPSSIVDEMRKSLIDTYV
Protein: Adaptin ear-binding coat-associated protein 2 (NECAP endocytosis-associated protein 2) (NECAP-2) (Q9D1J1)
Organism: Mus musculus (Mouse)
Function: Involved in endocytosis.
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000269|PubMed:14555962}. Cell membrane {ECO:0000269|PubMed:14555962}. Note=Colocalizes with AP-2 at the plasma membrane.
Interaction partners:
- AP-2 complex subunit mu
- AP-2 complex subunit beta
- AP-2 complex subunit alpha-2
- AP-2 complex subunit alpha-1
- AP-2 complex subunit sigma
- Epidermal growth factor receptor substrate 15
- Adaptin ear-binding coat-associated protein 1
- Epidermal growth factor receptor substrate 15-like 1
- SH3-containing GRB2-like protein 3-interacting protein 1
- Synaptojanin-1
Sequence:
MEESEYESVLCVKPEVHVYRIPPRATNRGYRASEWQLDQPSWSGRLRITAKGKVAYIKLEDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGLGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPDEGPKLDLGFKDGQTIKINIANMRKKEGAAGTPRARPTSAGGLSLLPPPPGGKSSTVIPPSGEQLSVGGSLVQPAVVSGSGGATELWPQSKPAAAATADIWGDFTKSTGSPSSQSQPGTGWVQF
Protein: Putative type II secretion system protein L (T2SS protein L) (Putative general secretion pathway protein L) (P45763)
Organism: Escherichia coli (strain K12)
Function: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Plays a role in the complex assembly and recruits GspM resulting in a stable complex in the inner membrane. Provides thus a link between the energy-providing GspE protein in the cytoplasm and the rest of the T2SS machinery.
Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:P25060}; Single-pass membrane protein {ECO:0000250|UniProtKB:P25060}.
Interaction partners:
- Putative type II secretion system protein M
- Putative type II secretion system protein F
- Putative type II secretion system protein E
- Putative type II secretion system protein C
- Type II secretion system protein H
- Putative type II secretion system protein K
- Type II secretion system protein J
- Type II secretion system core protein G
- Putative type II secretion system protein I
- Prepilin leader peptidase/N-methyltransferase
Sequence:
MPESLMVIRSSSTLRKHWEWMTFSADSVSSVHTLTDDLPLESLADQPGAGNVHLLIPPEGLLYRSLTLPNAKYKLTAQTLQWLAEETLPDNTQDWHWTVVDKQNESVEVIGIQSEKLSRYLERLHTAGLNVTRVLPDGCYLPWEVDSWTLVNQQTSWLIRSAAHAFNELDEHWLQHLAAQFPPENMLCYGVVPHGVAAANPLIQHPEIPSLSLYSADIAFQRYDMLHGIFRKQKTVSKSGKWLARLAVSCLVLAILSFVGSRSIALWHTLKIEDQLQQQQQETWQRYFPQIKRTHNFRFYFKQQLAQQYPEAVPLLYHLQTLLLEHPELQLMEANYSQKQKSLTLKMSAKSEANIDRFCELTQSWLPMEKTEKDPVSGVWTVRNSGK
Protein: Complement C1q tumor necrosis factor-related protein 5 (Q9BXJ0)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Membrane frizzled-related protein
Sequence:
MRPLLVLLLLGLAAGSPPLDDNKIPSLCPGHPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGDPGPRGEAGPAGPTGPAGECSVPPRSAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGESIASFFQFFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA
Protein: Protein X (HBx) (Peptide X) (pX) (P69713)
Organism: Hepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979) (HBV-A)
Function: Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC). Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation. This host complex would otherwise bind to viral episomal DNA, and prevents its transcription. Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
Subcellular location: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04074, ECO:0000269|PubMed:11468725, ECO:0000269|PubMed:7588604, ECO:0000269|PubMed:9572486}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04074, ECO:0000269|PubMed:11468725, ECO:0000269|PubMed:7588604, ECO:0000269|PubMed:9572486}. Host mitochondrion {ECO:0000255|HAMAP-Rule:MF_04074, ECO:0000269|PubMed:11257193}. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes. {ECO:0000255|HAMAP-Rule:MF_04074, ECO:0000269|PubMed:11257193, ECO:0000269|PubMed:9572486}.
Interaction partners:
Sequence:
MAARLYCQLDPSRDVLCLRPVGAESRGRPLSGPLGTLSSPSPSAVPADHGAHLSLRGLPVCAFSSAGPCALRFTSARCMETTVNAHQILPKVLHKRTLGLPAMSTTDLEAYFKDCVFKDWEELGEEIRLKVFVLGGCRHKLVCAPAPCNFFTSA
Protein: Bone morphogenetic protein 3 (BMP-3) (P49002)
Organism: Rattus norvegicus (Rat)
Function: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification (By similarity).
Subcellular location: Secreted.
Interaction partners:
- Activin receptor type-2B
Sequence:
MAGARGLLCLWLGCFCLNLAQGQRPNLHLPGLRGTESSDRMTGGGPSPDLRPHDKVSEHMLWLYDRYSGSNRAQATRTPGSQLPGPQPLRGGNTVRSFRAAAAGTLQRKGLHTFNLTSLTKSENILSATLYFYIGELVNTSVNCPESQGCSHDSQRQHIQIDLSAWTLQSNQSQLLGHLSVDTAKPYRDSMSWLSKDITQLLRKAKQDEEFLIGFNITSRAHELPKRMLLFPEPYILVYANDAAICEPESVVSSLQRHRDFTAGTVPRLDSHVREALSVERRKKRSTGILLPLQNNELPGAEYQYKEAGVWEERKPYKSLQTQPPEKSRSKKKQRKGPHQKGQTLQFDEQTLKKARRKQWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVSGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVDSCACR
Protein: Lysophospholipase (EC 3.1.1.5) (Q6FVF4)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Lysophospholipase 2
- Candida glabrata strain CBS138 chromosome J complete sequence
- Lysophospholipase NTE1
- Lysophospholipase 1
- Candida glabrata strain CBS138 chromosome L complete sequence
- Patatin-like phospholipase domain-containing protein
- Candida glabrata strain CBS138 chromosome G complete sequence
Sequence:
MLPSLFLVLVLVLCSGSSGYSVADQYAPKLAYCPSDDINLVREASGLSQNETQWLQRRDVRTKEALHNFLQRATSSSQNFTQLFHRIFDAGMVPRIGIAVSGGGYRSMLTGAGILSAFDNRTRGAMDHGLGGILQSTTYMTGCSGGNWLVASLSWNNWTSVQDILDMNYDRKTARKQGKITKDPIWDLSDSIVSPGGLNIIKTARRWDHITNAVKAKQEAGFNTSLADVWGRALSYKFFPTLERGGIDYTWSSLRDSPIFQAGDMPLPITVADGRYPGSNAIALNATVFEFNPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVAHTAKKCIEGFDNTAFIMGTSSNLFNQFLLRINSTHLPNFVTKWATNLLKSWAHEFNDVAVYNPNPFKDTRYVMENFSTSIVDSEHLYLVDGGEDDENVPLIPLLQRDRDLDIIFAIDNSADNKLQWPDGSSLVHTYERQFVLQGQKIAFPHIPDTNTFINLGLNKRPTFFGCNATNMTSLKYIPPLVVYYPNSEYSFNSNQSAFKLSYSRDQMANMISNGFEIATRNNFTDDPEFIGCIACAIMKRKQEALDLELPSECERCLARYCWDGTVDDTPLDELKQDVHHSFINPEEDKDGDGIDDYSDEDFTDDDVDDYHFFHYSNVDEIHHAATYTGKLLPTGAIDKGSNKPLINLSSKLGIPATSIAYAIVTFICTLSASLL
Protein: Dihydrouridine synthase 2 (H3BM64)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MILNSLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDDRVVFRTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMG
Protein: Prolactin-3B1 (Chorionic somatomammotropin hormone 2) (Placental lactogen II) (PL-II) (RPLII) (P09321)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted.
Interaction partners:
- Prolactin receptor
- Trophoblast specific protein alpha
- Cathepsin Q
- Endogenous retrovirus group FRD member 1, envelope
- Ctsq protein-like
Sequence:
MQLSLTQPCFSGTLLMLAVSTLLLWEQVTSAPNYRMSTGSLYQRVVELSHYTHDLASKVFIEFDMKFGRTVWTHNLMLSPCHTAAIPTPENSEQVHQAKSEDLLKVSITILQAWQEPLKHIVAAVATLPDGSDTLLSRTKELEERIQGLLEGLETILSRVQPGAVGSDYTFWSEWSDLQSSDKSTKNGVLSVLYRCMRRDTHKVDNFLKVLKCRDIYNNNC
Protein: receptor protein serine/threonine kinase (EC 2.7.11.30) (Q95L23)
Organism: Sus scrofa (Pig)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MLLRSSGKLNVGTKKEDGESTAPTPRPKILRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGMPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKTRDFVDGPIHHKALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGRWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMAPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASRLTALRVKKTLAKMSESQDIKL
Protein: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) (Q8WTS1)
Organism: Homo sapiens (Human)
Function: Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfert of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors (By similarity). Functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Regulates lipid droplet fusion (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18832586}. Lipid droplet {ECO:0000250|UniProtKB:Q9DBL9}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9DBL9}. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). {ECO:0000250}.
Interaction partners:
- Perilipin-1
- Patatin-like phospholipase domain-containing protein 2
- Perilipin-5
- Hormone-sensitive lipase
- Perilipin-2
- 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3
- Hydroperoxide isomerase ALOXE3
- Arachidonate 12-lipoxygenase, 12R-type
- Omega-hydroxyceramide transacylase
- Patatin-like phospholipase domain-containing protein 4
Sequence:
MAAEEEEVDSADTGERSGWLTGWLPTWCPTSISHLKEAEEKMLKCVPCTYKKEPVRISNGNKIWTLKFSHNISNKTPLVLLHGFGGGLGLWALNFGDLCTNRPVYAFDLLGFGRSSRPRFDSDAEEVENQFVESIEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILVEPWGFPERPDLADQDRPIPVWIRALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDDTVTEYIYHCNVQTPSGETAFKNMTIPYGWAKRPMLQRIGKMHPDIPVSVIFGARSCIDGNSGTSIQSLRPHSYVKTIAILGAGHYVYADQPEEFNQKVKEICDTVD
Protein: Receptor-type guanylate cyclase gcy-10 (EC 4.6.1.2) (Odorant response abnormal protein 1) (B1Q257)
Organism: Caenorhabditis elegans
Function: Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Regulates chemotaxis responses toward volatile odorants in AWC sensory neurons and their avoidance in AWB sensory neurons. May be involved in sensitivity to quinine by regulating egl-4 activity through the production of cGMP. Involved in phototransduction in ASJ neurons downstream of G protein coupled-photoreceptor lite-1. Required to maintain the expression of putative olfactory receptor str-2 in AWC neurons in adults. In AWB and AWC sensory neurons, mediates the recognition of food oders which subsequently allows for the detection of preferred food sources. Involved in AWB sensory neuron development and extension during postembryonic development, potentially via mediating localization of tub-1 and PI(4,5)P2 to membrane cilia.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, cilium {ECO:0000269|PubMed:10774726}. Note=Localizes in cilium of sensory neurons. {ECO:0000269|PubMed:10774726}.
Interaction partners:
- Guanine nucleotide-binding protein alpha-17 subunit
- Cyclic nucleotide-binding domain-containing protein
- Cyclic nucleotide-gated channel
- Guanine nucleotide-binding protein alpha-3 subunit
- cGMP-dependent protein kinase egl-4
- Cyclic nucleotide-binding domain-containing protein
- Homeobox protein ceh-36
- Cyclic nucleotide-binding domain-containing protein
- Cyclic nucleotide-binding domain-containing protein
- Probable 3',5'-cyclic phosphodiesterase pde-1
Sequence:
MLKSLLIIVIVFLHRELCDGIQLILFDNWPSAQNVCASAVADATANGQCTTKSIQKHLELLTVIILLKLFGVFHRINQQHGCSGDNSVKSASYAINAVASRTSGELDFVFVGPTCTTDIRTIGDFAEIWKSPVIGYEPVFEARGVQELTSVINVAQFSVGGVAETLVFLMKELEQVEITLVGSVKVLPNGLSLSNDLRSYNEIMNSFKIREYVEVDENDVDWTKVDQKIKRGARMIVVCADFYDIYSAFYNIGIRSLSGFRFIIVVILNKPPDEILNQPNVKNLLYGSNAFIISPLQEQYSDAFSIMQDVIPNLADDQFTTFLRIYHACYAYCVGSVNGAETQTDNYHTAMSGKAVTTKYGTFTFDNSGSVLTNYAVFTINPAEMTFESILTLKSVAKSCDTYNCFQLSPNKTSDLLWTLKDMDPPDDCVAKSSCVNYIPHIIAAVVIVTIIVIAIVIIVKQRRHKLNIYKLTWKVPKESLKIIVNKNADAKMQRELENRASNTDNAAALTSRRRVFGSYALVGTQRAEYVQFKQIRKINFPETTLDYLYSLKQLQHDNLAKFYGIQVNDDIMTMTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQYLHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKVPEQAAHMITYPQYVCFPPEHIREYDDSGKQPPRVVRGSPKGDIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNENHMPRITDDYRQENMLLEMCKECWDRNPDKRPTIKKLIESISTVYPLSKGNLVDQMIRMSEKYADELEQMVAIRTADLADAQMQTMRLLNEMLPASIAKDLKNGLIMPPRSYESATVMFVQICDFNALMKRSSPEQVIAFLNDIYDQFDTVIKRHDAYKVETTGETYMVASGVPHENEGRHIFEVAEISLEIREISYIYVLQHDKNYKLRIRIGFHAGPIAAGVIGIRSPRYCLFGDTVNFASRMQSNCPPNQIQTSEITARLLFDSHEYKFVKRGIVHVKGKGEVNCYWLNEHLHEETEPPLPPMTPVPNPLRRGSIVPLQKA
Protein: Leptin (Obesity factor) (U3GMG1)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MRCGPLXRFLWLWPYLSYVEAVPIXKVQDDTKTLIKTIVTRINDISHT
Protein: Beta-mannosyltransferase 8 (EC 2.4.1.-) (WRY family protein 3) (Q5AHD6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Beta-mannosyltransferase involved in cell wall biosynthesis through beta-1,2-mannosylation of cell wall phosphopeptidomannan (By similarity). Plays a role in the ability to produce hyphae in the presence of three bacterial species.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKFPKLRKRTVYWAVLTVFALFTIHFVFQYKEHNSHRVQPIVLIPKAFPSLILNSFDTQNEELVPIKLLKNCQIIRSYHTGYEENTKLLGQEPQSNFHKFNFTVFSSMKPIGLDLKQCQLLSSSSQVEVNDAVNMDASLHDILGKLLQDIRHGKLEYLQEIAPFFLPELQLQLNLNIVDRFWYRFSGSSIWLDQYNMYFMISRIAYSPHGVKNQPVVSLTYGQLFDRNWNEVKNINLLVPSNDPSKNGGHDSFRIISFPYFLPIPFWHDIDNTDGNYFGPEDPRLILVRNKQGYEEPLLIFNSYHRKFVHYDDDEDSIMGQTVKFQRSMFMCWPWQYQMGKSNVEGTSNPEYDNKVYNRVIELKVKLLADMKSQKNWTPFISEDSTNKFDSYIYFVYRWANLDVLKCSLLGDVAGDCVFDYRLDETLVPQNKVGPLRGGTQLVNLRQVIPRSVYHRLLPSHREIFIGFARTHLDNCGCGKVMYRPNLVILVKDAADKTYYKISHISSSLSFDVPIIGWNVYKPDDLCFDSNVLIPYSVSNWNITSLELDIEGGRWVSNDQLTLTLSISDSTVHRLDIRGLFQSILDLADRSLFIPVDRETRVIDEFQNGLQNPGSNPLNQDVNSLGVNNDNIVCALDASVEFCFEYGAKFSIPKQEEFYEVEQQEFNEELIDPKKHQYFKILGKYLYDHASVNS
Protein: Two-on-two hemoglobin-3 (AtGLB3) (2-on-2 hemoglobin-3) (Q67XG0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Hemoglobin-like protein that exhibits an unusual concentration-independent binding of O(2) and CO. May promote shoot organogenesis from root explants in vitro. Inhibits RGLG3 and RGLG4 ubiquitination activity.
Interaction partners:
- Anaerobic nitrite reductase AHB1
- E3 ubiquitin-protein ligase RGLG4
- At5g44730
- Anaerobic nitrite reductase AHB2
- AT4g27450/F27G19_50
- Thioredoxin superfamily protein
- Monothiol glutaredoxin-S17
- VQ motif-containing protein 19
- E3 ubiquitin-protein ligase RGLG3
Sequence:
MQSLQDKASVLSGVDQAEAFAIDESNLFDKLGLQTFINLSTNFYTRVYDDEEEWFQSIFSNSNKEDAIQNQYEFFVQRMGGPPLYSQRKGHPALIGRHRPFPVTHQAAERWLEHMQNALDDSVDIDQDSKIKMMKFFRHTAFFLVAGNELKNQNEKPKHKPQCACKHAANKPAEE
Protein: Polyadenylate-binding protein (PABP) (Q3UX16)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU362004}.
Interaction partners:
Sequence:
MNFDVMKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDESIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDSSGKSKGFGFVSYEKHEDANKAVEEMNGKEMSGKAIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPASAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSALRQSGPRPALRHLAPTGNAPASRGLPTTAQRVGSECPDRLAMDFGGAGAAQQGLTDSCQCWRRPYSRAKPCTSGRSCCRRSQGCGSIQVRLQLSAAALPAIQPLQAPQPAVQVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGTVAAATS
Protein: Cell division protein FtsX (Q81X30)
Organism: Bacillus anthracis
Function: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O34876}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O34876}.
Interaction partners:
- Cell division ATP-binding protein FtsE
- Peptidase M24
- Cell division protein FtsA
- Cell wall-binding protein
- N-acetylmuramoyl-L-alanine amidase
- Cell division protein FtsZ
- Septation ring formation regulator EzrA
Sequence:
MKAKTLSRHLREGVKNLSRNGWMTFASVSAVTVTLLLVGVFLTAIMNMNHFATKVEQDVEIRVHIDPAAKEADQKKLEDDMSKIAKVESIKYSSKEEELKRLIKSLGDSGKTFELFEQDNPLKNVFVVKAKEPTDTATIAKKIEKMQFVSNVQYGKGQVERLFDTVKTGRNIGIVLIAGLLFTAMFLISNTIKITIYARSTEIEIMKLVGATNWFIRWPFLLEGLFLGVLGSIIPIGLILVTYNSLQGMFNEKLGGTIFELLPYSPFVFQLAGLLVLIGALIGMWGSVMSIRRFLKV
Protein: Ethylene-responsive transcription factor ESR1 (Protein DORNROSCHEN) (Protein ENHANCER OF SHOOT REGENERATION 1) (Q9SAD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates gene expression patterns in meristems and thus modulates organ development. Required for correct embryo patterning and cotyledon organogenesis. Modulates auxin signaling pathway in early embryos. Involved in the cytokinin signaling pathway that promotes shoot regeneration. Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- WD repeat-containing protein PCN
Sequence:
MEKALRNFTESTHSPDPNPLTKFFTEPTASPVSRNRKLSSKDTTVTIAGAGSSTTRYRGVRRRPWGRYAAEIRDPMSKERRWLGTFDTAEQAACAYDSAARAFRGAKARTNFTYPTAVIMPEPRFSFSNKKSSPSARCPLPSLPLDSSTQNFYGAPAAQRIYNTQSIFLRDASCSSRKTTPYNNSFNGSSSSYSASKTACVSYSENENNESFFPEESSDTGLLQEVVQEFLKKNRGVPPSPPTPPPVTSHHDNSGYFSNLTIYSENMVQETKETLSSKLDRYGNFQANDDGVRAVADGGLSLGSNEWGYQEMLMYGTQLGCTCRRSWG
Protein: Ingression protein 1 (P53901)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the ingression of the plasma membrane into the bud neck at the end of cytokinesis, leading to the separation of the mother and daughter cells. Stimulates the synthesis of the primary septum (PS) by CHS2.
Subcellular location: Bud neck {ECO:0000269|PubMed:18344988, ECO:0000269|PubMed:19528296, ECO:0000269|PubMed:19707790, ECO:0000269|PubMed:20442249}. Note=Localizes at the contractile actinomyosin ring at the end of cytokinesis. Recruitment to the bud neck requires either CYK2 or CYK3.
Interaction partners:
- Cytokinesis protein 2
- Cytokinesis protein 3
- Myosin-1
- Ras GTPase-activating-like protein IQG1
- Chitin synthase 2
- High osmolarity signaling protein SHO1
- Tyrosine-protein phosphatase CDC14
- Cell cycle protein kinase DBF2
- Myosin light chain 1
- Serine/threonine-protein kinase DBF20
Sequence:
MSEEVWNGNQGILSVYVSKARDLPNLNKLDKQNVMLRLRIAHMTRASNTLHRAGQNPVFHYLEKFDITPEIKPLMYVEVYCDRRKKSPLPIGRCEIDLLNAIRADPKEGYCTWYELKRSGDEFAGTIFIELTFTPKVPRLNRDDLNKEMDRLDSSMAMRPIPPLPTESEYDYVHGSTMRQITPQCVSTSHEDKDEGQPYRNGNVFSMSSKSDTAVLANSNDPIILPPTFSASMGTTSTLETNDTAISNTSNTKFHFANLRKLKEKINIFKNPDSSTNNCQNESNKVDIEALQKAIGVTSLSYDEDDDDDDENDAFYSSSHRVSHNYNQPPLPPIPTRDDMSNYSSSRNTPLVRRDRPSRLDSSSPNSHPHPSGLNSPKLPPLPTTSNSNFNSRKNSMSPTRKRPPPRLS
Protein: Protocadherin 2C (Q9Z1B0)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MQRREDCKGLVFLGVLLGMLWKAGSTQIRYSVPEELEKGSRVGNISKDLGLKSCELAERGVRIVSRGRAQLFALNPRSGSLVTAGRIDREELCMGSIKCQLNLEILMEDIGKIYGVEIEVRDINDNAPYFRESELEIKMSENAAAGMRFPLPHAWDPDIGKNSLQSYQLSPNAHFSLEVQNGADGNKYPELVLESSLDREEKAAHLLVLTASDAGDPVRTGTARIRVMVVDANDNAPAFARSEYRVSWENVAVGTQLLLVNATDPDEGANAEVIYSFRYVDDKAAKVFKLDSNLGTISTIGELNHEESGFYEMEVQATDNAGYSARAKVLVTVLDVNDNAPEVAITSLTNSVPENSPQGTLIALLNVNDQDSGENGQVICSIQENLPFKLEKSYGNYYRLVTDAVLDREEVPSYNITMTATDRGSPPLTTETHLALDIADTNDNSPVFLQASYWAYIPENNPRGASIASVTAHDPDSDKNAQVTYSLAEDTHQGVPLSSYVSINSDTGVLYALHSFDYEQFPDLQLQVIARDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTLPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEISTARALMDRDALKQNLVVSVQDHGQPPLSATVTLTVAIADSIPDVLADLDNLESPSTSETSGLTLYLVVAVAAVSTVFLVFVLVLLALRLRRWHSLRLLRAGGPGLADVAASHFVGVDGVQAFLQTYSHEVSLTAGSRKSHLIFPQPNYADTLISQESCEKTEPLLPSGDSVFSKDNHALNQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Protein: Alpha N-terminal protein methyltransferase 1 (EC 2.1.1.244) (X-Pro-Lys N-terminal protein methyltransferase 1) (Q584S3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Methyltransferase
- EMG1/NEP1 methyltransferase
- Cytochrome-c oxidase
Sequence:
MPARGCAPVDEQIAGTDTEGRRYRSVEEMWGRELQGNLYDAKTGWYGKSLQYWGSVPATVSGVLGGMDHVHDIDIRDSRAFICCLPERGTTRALDCGAGIGRITKSLLCHLYDVTDLLEPVASMLEKAKEELEGFPVGDFFQSSMETAKLQPKTYDLIVIQWAAIYLTDEDFVAFLVRCKEALTPKGYIFFKENCASDDEFIVDKEDSSLTRSDKHYKRIFAAAGIEVVKEAMQGDWPDDLLKVKMYALR
Protein: Cysteine-rich venom protein 24 (CRVP-24k) (P84803)
Organism: Naja kaouthia (Monocled cobra) (Naja siamensis)
Subcellular location: Secreted {ECO:0000269|PubMed:15670767}.
Interaction partners:
Sequence:
VDFASESXNKRENQQIVDKHNAL