wanglab/gogpt-training-data huggingface dataset:
Protein: Leucine-rich repeat-containing protein 14 (Q15048)
Organism: Homo sapiens (Human)
Function: Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:27426725}.
Interaction partners:
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Transcription factor E4F1
- Dol-P-Man:Man
Sequence:
MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGSSLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFSL
Protein: Acetyl esterase (EC 3.1.1.-) (C4ZUT0)
Organism: Escherichia coli (strain K12 / MC4100 / BW2952)
Function: Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01958}.
Interaction partners:
Sequence:
MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYYTLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDTHDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLAAHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL
Protein: Stretchin-MLCK (Q9NBB4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
KPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSEIVSEKITVEKAQESQKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAIDEKSQKAEVSETVSEKITDEKAQESQKKEVKDSEAKPKKAKILEKKSIEIEKXVEKKKKKTR
Protein: N-Acetyl-D-Glucosamine phosphotransferase system transporter (Q9HXN4)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- phosphoenolpyruvate--protein phosphotransferase
- Probable N-acetylglucosamine-6-phosphate deacetylase
- phosphoenolpyruvate--protein phosphotransferase
- Phosphocarrier protein HPr
- protein-N
- Probable transcriptional regulator
- Probable aminotransferase
- Phosphofructokinase
- Nitrogen regulatory protein
- Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
Sequence:
MPPFLIESLQRLGRALMLPIAILPIAGLLLRLGDVDLLDIPLVHDAGKAIFANLALIFAIGIAVGFARDNNGTAGLAGAIGYLVMISVLKVIDPGIDMGVLSGIISGLVAGALYNRFKDVKLPEYLAFFGGRRFVPIATGISAVCLGLLFGVIWPPLQQGINGLGQLMLESGSFGAFAFGVLNRLLIVTGLHHILNNLVWFVFGSFTDPETGRVVTGDLARYFAGDPKGGQFMAGMFPVMMFGLPAACLAMYRNARPERRKLIGGLLLSMALTAFLTGVTEPVEFAFMFLAPLLYLLHALLTGLSMALTDLLDIRLGFTFSGGAIDLALGWGRSTHGWMLWPLGLLYAGIYYLVFDFCIRRFNLKTPGREDDASSESGDNAEAERAPAFIRALGGAANLEVVDACTTRLRLRLVDRNKASDAQLKALGAMAVVRPGKAGSLQVVVGPQADSIADEIRRALPFDTQPGEAVPPLGSPHTAEEVVAMQATVDAAEAQAWLGALGGAGNLREVRDVALTRLRVSVADERKLATEQLRRLGGQGVSSLAGGICHILVGPRAAALSQALQPLLRR
Protein: CCR4-NOT transcription complex subunit 4 (Q9GYQ9)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSTCSDESCDKECPLCMETLELDDINFYPCKCEYQICRFCWHRIRTDENGLCPACRQPYPEDPVNFKPMTTDDVRKHKDEQRLKKQAEKLKLSDARQYLCNYRVLQKNLVYVVGLSPRVADPEILKKNEYFGRYGKIQKIVTSATPSLPAPHLPPSHTAYVTYKRVDDALRAIQGVHNSMLDGRLVKASLGTTKYCSSFLNSRKCFKPVGECMYLHENAEAEISFTKDDMHLGKHTEYEKRLIESMNSRPPPPQSTLASQLDKILAPTSNSPRRYLEDDSDTVDDVERTGSAIHMCADDPDDDDADSTNTSNSIDDPAPSNPADETVNSRRSNQTARERQWSERDEISVAPSNTPPTDPEGNENEFEEDIHRNDVSDLMSKLDVNDDRLARTSFSENDYLGIPAPAKHQEAPAPLMQWEALLGLSSPSAQSTIVEPSSLFPTFKMDSGFNSQSLFGTHTSSTPSFRREASPPPGLARFNSDDDLGFDPFTESSKGLSALLQEEQEQIPPHNSASNHTLDVLKQLFGQLPEQRQSTQQHPQHLQSSHQQHPLQQNQDQHHSFLHQLHAQQQHQQQQFAADMNRQQDYMYSRLMSQQQQQSQQQRQFDSTPGFSHPFGSMQQQQQSSQQQQHQSQSSQSSSLLQDLFNRQQQQHQAQQQAQQHQQQQMYAGINSYMYNDMLMPRVPFGMAPPPGLGGPSTNRSSTTQQAPPHMTQQSQQQQQQQQSSMGLFGMGGHQSMMQDHQSQQPQSAQDAFKALLPNVNVRFMDDNSMSRWSHENSLRSSAVPPPPGFSSVMNR
Protein: Zinc finger and BTB domain-containing protein 16-A (Promyelocytic leukemia zinc finger protein-A) (Zinc finger protein PLZF-A) (Q802Y8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Probable transcription factor. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Inhibits neurogenesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:20080956}. Cytoplasm {ECO:0000269|PubMed:20080956}. Note=Nuclear export to the cytoplasm is promoted by btbd6a. {ECO:0000269|PubMed:20080956}.
Interaction partners:
Sequence:
MDLTKMGMIQLQNPNHPNALLHKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKVEDLDDLLYAAEILEIEYLEEQCLKILETIQSSDENDTEVNMNDGGTEDDEERKGRHGRNLVGSKKHSTEESGYVSAAQQALALPGMVDQSPSVSTSFGLSTMSPTKAAVDSLMSIGQSLLQSTMHPGVGAEQPLHGNSHPMMGEIKTEMMQVDESGEHESPKAMESIASSNGERSGEPDKNRDGPGTPTRSSVITSARELHYVRDEGLGDQQAEVSQMGLEAMAGMTEKHLASLYGIPSNHKNEAMLSMPASMASSLHMSPALAMSMDFSAYGGLLPQSFIQREFFSKLGELAAGIKPDGRSLNERCNVCGAELPDNEAIEQHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLSHSAGEKAIVCDQCGAQFQKEDALEAHRQIHTGSDMAIFCLLCGKRFQTQTALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHTAGDHPFECEFCGSCFRDESTLKGHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICLEYCPSLSAMQKHMKGHKPEDIPPDWRIEKTYLYLCYV
Protein: Ensconsin, isoform G (M9PHB1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASLGGQHGNISTNPEVENTAKRPESREGSAERKDREEKLKYARDRQNEERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKAIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDRQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPHPPPTSKQTANAHRPTNLTTTTATSTTTAGHNNFNNNNSYRKEDSVDSSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSAGSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQRDSTSSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTITKPAPAPVAPTSAPVPEQNGVAKEVEKTTADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEEGARQEEEQILAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAATAPENNSSSNSSVTGSSNNSAEGSPSAADSTPAPTATETVQEAPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNGKLLVDFESTNTVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL
Protein: Glyceraldehyde-3-phosphate dehydrogenase 1 (EC 1.2.1.12) (Glyceraldehyde-3-phosphate dehydrogenase I) (GAPDH I) (P07486)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm.
Interaction partners:
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase 2
- Enolase
- Phosphoglycerate kinase
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Pyruvate kinase
- Fructose-bisphosphate aldolase
- Malate dehydrogenase, mitochondrial
- ATP-dependent 6-phosphofructokinase
Sequence:
MSKIGINGFGRIGRLVLRAAIDKGASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYVVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYSPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPAATGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGATYDEIKAKVEEASKGPLKGILGYTDEEVVSTDFFSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKD
Protein: Protein Wnt (A5WVL3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
Interaction partners:
- Frizzled-4
- Low density lipoprotein receptor-related protein 5
- Frizzled class receptor 6
- Porcupine O-acyltransferase
- Frizzled-3
- Frizzled class receptor 1
- Frizzled class receptor 2
- Frizzled-5
- Secreted frizzled-related protein 1
- Wnt inhibitory factor 1
Sequence:
MDNTGCGIHAVHHLFLIWLSVYPLCSQGSWMWLGITSVGVPEKLGCAHLPLSHKQKELCARKPHLLPSVKEGARLGITECQTQFRHERWNCSTRRDPNVFGYELTSGTKETAFIHAVMAAGLVHAVTRSCSAGNMTECSCDTSLLGSGSPTEGWHWGGCSDDIAFGTSFSRRFIDSAAKNTSTRGEEALLIMKQHNSEAGRQAVAKTMLTDCRCHGVSGSCAVKTCWRTMAAFERVGAYLKDRYETSVHVVDRSKRKVRRKDKEQRHVPITKDELIFFNKSPNYCLEDRRLGVTGTRGRKCNRTSAGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMNDMHTCK
Protein: DNA-directed RNA polymerase subunit Rpo4 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit F) (Q7LXK4)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00864}.
Interaction partners:
- DNA-directed RNA polymerase subunit Rpo7
- DNA-directed RNA polymerase subunit Rpo5
- DNA-directed RNA polymerase subunit Rpo10
- DNA-directed RNA polymerase subunit Rpo12
- DNA-directed RNA polymerase subunit Rpo1N
- DNA-directed RNA polymerase, subunit B''
- DNA-directed RNA polymerase subunit Rpo3
- DNA-directed RNA polymerase subunit Rpo11
- DNA-directed RNA polymerase subunit Rpo6
- DNA-directed RNA polymerase subunit Rpo1C
Sequence:
MSSVYIVEEHYIPYSVAKKLLTDVIRSGGSSNLLQRTYDYLNSVEKCDAESAQKVIEELSNIVSREDVRAILASICPTTSDEVRSILVMDTNKTYTSEDIQKIIDIIRKYIKS
Protein: ATP-dependent protease ATPase subunit HslU (Heat shock protein HslU) (Unfoldase HslU) (P0A6H5)
Organism: Escherichia coli (strain K12)
Function: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
Subcellular location: Cytoplasm.
Interaction partners:
- ATP-dependent protease subunit HslV
- ATP-dependent Clp protease proteolytic subunit
- Chaperone protein DnaJ
- Protein GrpE
- Chaperone protein ClpB
- Chaperonin GroEL
- Chaperone protein DnaK
- Chaperone protein HtpG
- Co-chaperonin GroES
- Lon protease
Sequence:
MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL
Protein: Large ribosomal subunit protein bL34m (39S ribosomal protein L34, mitochondrial) (L34mt) (MRP-L34) (Q99N91)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9BQ48}.
Interaction partners:
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein uL16m
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein uL30m
- Large ribosomal subunit protein mL41
- Small ribosomal subunit protein uS15m
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein bL33m
Sequence:
MAFLARCFGCQACRSVALLSGRYLQSRVWMGLPDSWPLLSLQQARGRARGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH
Protein: Coiled-coil flagellar protein (Q8S4W6)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Interaction partners:
- Sperm-associated antigen 6
- ODAD1 central coiled coil region domain-containing protein
- Dynein-1, subspecies f
- Uncharacterized protein
- DUF4200 domain-containing protein
- Dynein axonemal intermediate chain 4
Sequence:
MDDDILGLEDVTASEAFKIIYELSKASKIDADRSDAAKAQFTLLHSTLLQALQAERDLLDQAKALKRQKEEQEAAITGAGGVPGADDIDQLREDVEAALGEAALAQERQQLLQLEVTDLQRQRNDLGARMEELAAEHAAALQPVIAQARGEAAALVDELDEERRRVEAAHGELEDMKSKLAAVQEEIEAMGETKAVERANLVKVDPLPDKARRQSEAVAAILKSVQGQLESMNARYGEHDTQYKTAAEREQQLTEEHTKMLTALERGRVQVESKARHADDVRKDVELASIEADKILADQVELDLRVKNLALELKAESDHLNRRQREKELMLRQYRVADQQLKDARDMLPNLKFQVEQMHRDVNTLEARRRAQSRELSDVKRELDIQMAAFLHEEADGKEKVALFQLTYKEVAALEAELAALKREEAERDTILRDLGSQRDRVALAIAQKLSKVKDVQMTSRIKEVELAELKKIRKEVGRRIRDFEKLYDLVKNQRNKFVNLIQAASQSTTEMKDKLKVLQNELDILQNEVGIKDKLLQQQHTQHAANIAERDQLRVELGRLGMVFRDKQAVVDEQIAEVDKLNAIINGCEKEMLRLKKQYELVIEARNYTGIMLIDRNDELCVLYEKANILDEVIKSGQLELMRREDEARLLRLEVGELERSIGVTRRLVPSVPLLDNDVAALQKALFEARREAEALSLALENPSNQGRWRLLEGKIPDREELSAKIQALEERLNDKKEQLLEKELILEEITSLSDKLRVQAAEGRADTLELAQRVNEYQSKLRAVTRKIMATVSELSMYQASALKLGAEKEELEGAVSLASQRLEAGEPPTDDAEREWYRLERERHTVDAMAEERRAVAAALDARVAEVQSTAEPRPNAYIPEQLGIPKPYGSFAPFKPQEAGSTMRHIRKPSPKEVVI
Protein: Cytochrome c-552 Ks_3358 (Similar to cytochrome c6) (Q30JB5)
Organism: Kuenenia stuttgartiensis
Interaction partners:
Sequence:
MKNKNTLTLALFSVTIGASAFFFGTSVSKASNIDGMKLYLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFKK
Protein: Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NESK) (NIK-like embryo-specific kinase) (Q9R0G8)
Organism: Mus musculus (Mouse)
Function: May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway.
Interaction partners:
Sequence:
MAGPGSWRDKEVTDLGQLPDPTGIFSLDKAIGLGTYGRIFLGIHEKTGSLVAVKVMSARKTPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLWMVMELCAAGSVTDVVRMTRNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTHDAEVKIVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGITAIEMAEGAPPLCKLQPLEALCVILREAAPKVKSSGWSRKFQNFMENCMIKNFLFRPTSGNMLLHPFVHDIKNERRVVESLTKHLTGIIQKREKKGIPVAFEGEEAAKEQYITRRFRGPSCTPELLRVPTSSRCRPLRVLHGEPPQPRWLPDQEDPQDQELQQLQKAAGVFMPLHSQDNTSKLFPKQVEVAPYLRGAAQVVMPVLVQVEAPPQVSKAAQMLKSLPTQDNKATSPEVQAPVAEGQQAQHEALETEQPKDLDQVPEEFQGQDRAPEQPRQGQAAEQQQIHNPVPEQPPEEDREPEQAEVQEEAVEPPQAEIEDKEPEVVQVHAQVLLPLLSQNRHVLLPLHLDRQLLIPVGEQNEEVPRAQAWDLEASRAVGAVQALIEGLSRDLLRAPNAFVTKPLGPLQIFLENLSTDGFYTEPEPTQKKKSKVASLRKAIAKRLRPKRFRAKALWRLEDFEFSDVETSRRRRHRRWEDIFNQHEEQLRRVENDREDDSSDNDEVFHSIQAEVQIEPHAANPAGNEVHERSAPMPCNRNRTHRVKFSPSVGEEEPSLEEAQPQQQQQQPMNIRPRNCLNPQNFQAQSDSSSEEDSPVTRRKSQSSPPYSTIDQKLLIDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIFWDDWIMPTRPARPPEEDGDYVELYDADANANGDEEVANGAYEDPRDGANGHDDMNNQLDQANGYEGHGAAGYNGGDVGGNHGAAFNGPRANYPRAGILKNGHNDGRALNRGAFGVFGDNAARAFHGAAGEAGAAFGNHGANRGNGRGNRNREANGRNEENGAFGRDQHVFPEFEHEESDRGTETSDSIALEITSFDGEQNSGRPVSSTTMGFPIGRSSPRGSDFGSDISYNSPILHVYEKDFSSEVYCGSLWGVNLLLGTQSHLYLMDRSGKAEIVKLIKRRPFRQIQVVEQLNLLITISGKKNRLRVYHLSWLRNKILNNDPKSKKRQKAMRKKEEACKAIDKLIGCEHFSVLQHEETTYIAVAVKSSIHLFAWAPKSFDENTAIKVFPTRDLKPLTVDLAVGSEKTLKIFFSSANGYHIIDAESEVMSEVTLPNNNVVILPDCLGLGVMLSLNAEAASEEANEQLLKKILDVWKDIPSSVAFECTKRITGWDQKAIEVRSLQSTILENELKRRSIKKLRFLCARGDKMFFASTLSNDHSRVYLMSLGKLEELHRSYAV
Protein: Band 7 domain-containing protein (Stomatin-like protein UNC-1) (G5ED08)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MSNKERTEPQWVTPSSNQVSQQDVPPDYETIGTIFGYALQALSWILIIVTFPFSMCVCLKVIKEYERVVIFRIGRLVFGGARGPGMIFIIPCIDTYRKIDLRVVSYAVPPQEILSKDSVTVSVDAVVYFRTSDPIASVNNVDDAIYSTKLLAQTTLRNALGMKTLTEMLTEREAIAQLCETILDEGTEHWGVKVERVEVKDIRLPQQLTRAMAAEAEAAREARAKVVAAEGEQKASRALKEAADVIQANPVALQLRHLQALNSIAAEHNSTIVFPVPVEMFGAFMKKDQ
Protein: Tropomodulin 1 (G1T676)
Organism: Oryctolagus cuniculus (Rabbit)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Nebulin
- Adducin 2
- Adducin 3
- Ammonium transporter Rh type A
- Tropomyosin alpha-1 chain
- Protein 4.2
- Nebulette
- Gelsolin
- Myosin light chain 1/3, skeletal muscle isoform
- Spectrin alpha chain, erythrocytic 1
Sequence:
MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLETVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLSSVIKPTQYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKDNSHVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPHNTSLVELKIDNQSQPLGNKVEMDIVSMLEKNTTLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPRCRSGV
Protein: Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) (O88576)
Organism: Mus musculus (Mouse)
Function: Symporter that transports one amino acid molecule together with two sodium and one chloride ions in kidneys and plays a role in the neutral amino acids reabsorption. Preferentially transports neutral amino acids such as L-glycine and L-alanine but also other neutral amino acids. Required CLTRN for cell surface expression and for its amino acid transporter activity. The transport mechanism is pH-independent.
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:19478081, ECO:0000269|PubMed:20377526}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:20377526, ECO:0000269|PubMed:26240152}; Multi-pass membrane protein {ECO:0000255}. Note=In kidneys localizes to the apical membrane in distal segments of the proximal tubule (PubMed:19478081, PubMed:20377526). Cell membrane expression is CLTRN-dependent (PubMed:20377526). {ECO:0000269|PubMed:19478081, ECO:0000269|PubMed:20377526}.
Interaction partners:
- Collectrin
- Angiotensin-converting enzyme 2
- Proton-coupled amino acid transporter 2
Sequence:
MAQASGMDPLVDIEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVFEGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTVLLWVLWFFLNSFQHPLPWSTCPLDLNRTGFVQECQSSGTVSYFWYRQTLNITSDISNTGTIQWKLFLCLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFTPNMKTLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAIFSVMGFKASNDYGRCLDRNILSLINEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKTCHLEDFLDKSASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLDMGILPKGIPKEVMTGVICFACFLSAICFTLQSGGYWLEIFDSFAASLNLIIFAFMEVVGVIHIYGMKRFCDDIEWMTGRRPGLYWQVTWRVVSPMLLFGIFLSYIVLLIQTPPSYKAWNPQYEHFPSREEKFYPGWVQVTCVLLSFLPSLWVPGVALAQLLSQYKQRWKATHLESGLKLQESRGC
Protein: Subtilisin-like protease 3 (SbtM3) (Subtilase 3) (EC 3.4.21.-) (A9QY39)
Organism: Lotus japonicus (Lotus corniculatus var. japonicus)
Function: Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular location: Secreted, extracellular space, apoplast {ECO:0000250|UniProtKB:A9QY40}. Note=Accumulates in the intercellular spaces and the periarbuscular space (PAS) during arbuscular mycorrhizal (AM) symbiosis. {ECO:0000250|UniProtKB:A9QY40}.
Interaction partners:
Sequence:
MTKVVQFSLLLALILVLSVSLASAASQNLEFTELEDEDQSNLSTYIVHVRKPQVIQSDDLHTFYYSLLPESTKTTNQRIVFTYRNVVNGFAVKLTPEEAKALQQNEEVVSARPEKILSLHTTHTPSFLGLQQGLGLWKGSNSGKGVIIGILDTGISPFHPSFSDEGMPSPPAKWNGICEFTGKRTCNNKIIGARNFVKTKNLTLPFDDVGHGTHTASTAAGRPVQGANVYGNANGTAVGMAPDAHIAMYKVCGLVGCSESAILAGMDTAVDDGVDVLSLSLGGPSGPFFEDPIALGAFGAIQKGIFVSCSAANSGPAYSSLSNEAPWILTVGASSIDRTIMATAKLGNGKEYVGQSVFQPKDFAPSLLPLVYAGANGNNNFSVFCAPESLNRSDVEGKVVLCEDGGFVPRVFKGKAVKDAGGAAMILMNSVLEDFNPIADVHVLPAVHISYEAGLALKEYINSTSTPTATILFEGTVIGNLLAPQVTSFSSRGPSKASPGILKPDIIGPGLNILAAWPVSLDNSTTPPFNIISGTSMSCPHLSGIAALLKNSHPDWSPAAIKSAIMTTASQVNLGGTPILDQRLVPADVFATGAGHVNPVKANDPGLVYDIEPNDYIPYLCGLNYTDREVGVILQQRVRCSEVNHIAEAELNYPSFSILLGNTTQLYTRTVANVGPANSTYTAEIGVPVGVGMSLSPAQLTFTEVGQKLTYSVSFIPFSEDRDNHTFAQGSLKWVSGKYSVRSPISFIFL
Protein: rhamnogalacturonan endolyase (EC 4.2.2.23) (Q9STV1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Tetratricopeptide repeat
- AT3G18790 protein
- ATPase E1
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- Peptidyl-prolyl cis-trans isomerase CYP18-2
- Transcriptional regulator ATRX
- AT4g21110/F7J7_50
- Cell division cycle 5-like protein
- Cwf15 / Cwc15 cell cycle control family protein
- Pre-mRNA-splicing factor SYF2
Sequence:
MSNQDSVQLDVQESHVVMGNGKVKVTISKPDGFVTGISYQGVDNLLETHNEDFNRGYWDLVWSDEGTPGTTGKSERIKGTSFEVVVENEELVEISFSRKWDSSLQDSIAPINVDKRFIMRKDVTGFYSYAIFEHLAEWPAFNLPQTRIVYKLRKDKFKYMAIADNRQRKMPLPEDRLGKRGRPLAYPEAVLLVHPVEDEFKGEVDDKYEYSSENKDLKVHGWISHNLDLGCWQIIPSNEFRSGGLSKQNLTSHVGPISLAMFLSAHYAGEDMVMKVKAGDSWKKVFGPVFTYLNCLPDKTSDPLSLWQDAKNQMLTEVQSWPYDFPASEDFPVSDKRGCISGRLLVCDKFLSDDFLPANGAFVGLAPPGEVGSWQLESKGYQFWTEADSDGYFAINDIREGEYNLNGYVTGWIGDYQYEQLINITAGCDIDVGNIVYEPPRDGPTVWEIGIPDRSAAEFFVPDPNPKYINKLYIGHPDRFRQYGLWERYTELYPKEDLVFTIGVSDYKKDWFFAHVTRKMGDDTYQKTTWQIKFKLENVQKSCTYKIRIALATANVAELQVRMNDDDTEKTTPIFTTGVIGHDNAIARHGIHGIYRLYNVDVPSEKLVEGDNTLFLTQTMTTTGAFNGLMYDYIRLEGPPLDSYSH
Protein: Sucrose synthase 6 (AtSUS6) (EC 2.4.1.13) (Sucrose-UDP glucosyltransferase 6) (Q9FX32)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:19470642}.
Interaction partners:
- Granule-bound starch synthase 1, chloroplastic/amyloplastic
- Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic
- Glucose-1-phosphate adenylyltransferase large subunit 3, chloroplastic
- Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic
- Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic
- Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic
- alpha-D-xyloside xylohydrolase
- UTP--glucose-1-phosphate uridylyltransferase 1
- UTP--glucose-1-phosphate uridylyltransferase 2
- Beta-fructofuranosidase, insoluble isoenzyme CWINV2
Sequence:
MSSSSQAMLQKSDSIAEKMPDALKQSRYHMKRCFASFVGGGKKLMKREHLMNEIEKCIEDSRERSKILEGLFGYILTCTQEAAVVPPFVALAARPNPGFWEYVKVNSGDLTVDEITATDYLKLKESVFDESWSKDENALEIDFGAIDFTSPRLSLSSSIGKGADYISKFISSKLGGKSDKLEPLLNYLLRLNHHGENLMINDDLNTVAKLQKSLMLAVIVVSTYSKHTPYETFAQRLKEMGFEKGWGDTAERVKETMIILSEVLEAPDNGKLDLLFSRLPTVFNVVIFSVHGYFGQQDVLGLPDTGGQVVYILDQVRALEEELLIRINQQGLGFKPQILVVTRLIPEARGTKCDQELEAIEGTKHSHILRVPFVTNKGVLRQWVSRFDIYPYLERFTQDATSKILQRLDCKPDLIIGNYTDGNLVASLMATKLGVTQGTIAHALEKTKYEDSDAKWKELDPKYHFSCQFTADLIAMNVTDFIITSTYQEIAGSKDRPGQYESHTAFTMPGLCRVVSGIDVFDPKFNIAAPGADQSVYFPYTEKDKRFTKFHPSIQELLYNEKDNAEHMGYLADREKPIIFSMARLDTVKNITGLVEWYGKDKRLREMANLVVVAGFFDMSKSNDREEKAEIKKMHDLIEKYKLKGKFRWIAAQTDRYRNSELYRCIADTKGVFVQPALYEAFGLTVIEAMNCGLPTFATNQGGPAEIIVDGVSGFHIDPNNGDESVTKIGDFFSKCRSDGLYWDNISKGGLKRIYECYTWKIYAEKLLKMGSLYGFWRQVNEDQKKAKKRYIEMLYNLQFKQLTKKVTIPEDKPLPLRLASLRNLLPKKTTNLGAGSKQKEVTETEKTKQKSKDGQEQHDVKVGEREVREGLLAADASERVKKVLESSEEKQKLEKMKIAYGQQHSQGASPVRNLFWSVVVCLYICYILKQRFFGANSAQEY