wanglab/gogpt-training-data huggingface dataset:
Protein: Pentatricopeptide repeat-containing protein At1g30610, chloroplastic (Protein EMBRYO DEFECTIVE 2279) (Q9SA76)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in embryogenesis.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Protein REDUCED CHLOROPLAST COVERAGE 3
- Cytosolic sulfotransferase 5
- CASC3/Barentsz eIF4AIII binding protein
- Embryo defective 2737
- Alanine--tRNA ligase, chloroplastic/mitochondrial
- FAD/NAD
- SEED MATURATION PROTEIN 1
- Pentatricopeptide repeat-containing protein At3g49170, chloroplastic
- Aspartic proteinase PCS1
- Ankyrin repeat domain-containing protein EMB506, chloroplastic
Sequence:
MAVTISTNAFVNASLLDESRNSFWRPLFHQPYYNCRRVVRLNSRKLNSKVMFCLNLNTKEVGLQKPGDKGFEFKPSFDQYLQIMESVKTARKKKKFDRLKVEEDDGGGGNGDSVYEVKDMKIKSGELKDETFRKRYSRQEIVSDKRNERVFKRNGEIENHRVATDLKWSKSGESSVALKLSKSGESSVTVPEDESFRKRYSKQEYHRSSDTSRGIERGSRGDELDLVVEERRVQRIAKDARWSKSRESSVAVKWSNSGESSVTMPKDESFRRRYSKQEHHRSSDTSRGIARGSKGDELELVVEERRVQRIAKDVRWSKSDESLVPVSEDESFRRGNPKQEMVRYQRVSDTSRGIERGSKGDGLDLLAEERRIERLANERHEIRSSKLSGTRRIGAKRNDDDDDSLFAMETPAFRFSDESSDIVDKPATSRVEMEDRIEKLAKVLNGADINMPEWQFSKAIRSAKIRYTDYTVMRLIHFLGKLGNWRRVLQVIEWLQRQDRYKSNKIRIIYTTALNVLGKSRRPVEALNVFHAMLLQISSYPDMVAYRSIAVTLGQAGHIKELFYVIDTMRSPPKKKFKPTTLEKWDPRLEPDVVVYNAVLNACVQRKQWEGAFWVLQQLKQRGQKPSPVTYGLIMEVMLACEKYNLVHEFFRKMQKSSIPNALAYRVLVNTLWKEGKSDEAVHTVEDMESRGIVGSAALYYDLARCLCSAGRCNEGLNMVNFVNPVVLKLIENLIYKADLVHTIQFQLKKICRVANKPLVVTYTGLIQACVDSGNIKNAAYIFDQMKKVCSPNLVTCNIMLKAYLQGGLFEEARELFQKMSEDGNHIKNSSDFESRVLPDTYTFNTMLDTCAEQEKWDDFGYAYREMLRHGYHFNAKRHLRMVLEASRAGKEEVMEATWEHMRRSNRIPPSPLIKERFFRKLEKGDHISAISSLADLNGKIEETELRAFSTSAWSRVLSRFEQDSVLRLMDDVNRRLGSRSESSDSVLGNLLSSCKDYLKTRTHNL
Protein: Uncharacterized methyltransferase C3B9.04, mitochondrial (EC 2.1.1.-) (O43033)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable methyltransferase.
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- ATP-dependent rRNA helicase spb4
- Uncharacterized mitochondrial carrier C1442.03
Sequence:
MGILKKTIFIGGIYGLGVYIGAVAWRLRKDVLNYESRQKSDLLIPNSNSISIYNQIADKYSRKITREEIFSGIYFLRYFLLRNAKGDVLEVGSGPGTNFPFYKWKKINTLTLVEPAEKMREIADARAKKKVPPNVLYRQFADLRQLPPNQSYDTIIQTFCICSQEKAVEQLNNYRSLLRSDGRILLIEHGKGKYKFLNRILNAYAESHYESWGCVWNRDIEQLLEDSELTIDSCKRFNFGTTYVIEAH
Protein: Os01g0797600 protein (cDNA clone:006-304-H01, full insert sequence) (Q7F4G5)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAPRAATVEKVAVAPPTGLGLGVGGGVGAGGPHYRGVRKRPWGRYAAEIRDPAKKSRVWLGTYDTAEEAARAYDAAAREFRGAKAKTNFPFASQSMVGCGGSPSSNSTVDTGGGGVQTPMRAMPLPPTLDLDLFHRAAAVTAVAGTGVRFPFRGYPVARPATHPYFFYEQAAAAAAAEAGYRMMKLAPPVTVAAVAQSDSDSSSVVDLAPSPPAVTANKAAAFDLDLNRPPPVEN
Protein: MGT1 magnesium transporter (Q4QF51)
Organism: Leishmania major
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- MGT2 magnesium transporter
- Related to multifunctional cyclin-dependent kinase pho85-like protein
Sequence:
MSSNASKTETPASLLAEDATMTSLDRLTNLGTSIFFTPPSVEHPSAASELGSSHAPPPPRVQDLANVVLPLASAEARVSNVLSFARRPLEIVESIKGLHELHQKGGLTREEFAQAKQQILDSAASSASTYKSKSKRSRGRRHRRRGRRSRNSSRSASTSTRTRPSRNARSRATTGVDTRSASHRPSRSSSSSKSSSSSSSSSSNRFIIVPRSNVWRTLNDPIEGLLGHHSTEGHHVRVAYNDAPRLVRSPLLSRGGAVVGFGSRERGGQEECCAGAHGRHGYQEIPSEDPLTSNLASGAAVPTPTLATAPGTKDGVFASPSGSAIGAATAATGSSVARYATVPDGRGKATYGAFLHRDDDARAGGPAPHIHAVLNKEDVVCIQYFNSRGGSGNHFRDVELHTSQLRDPIFVHKGQSQVIPAKPRTSVAKPSRDEPVMMAMPTRDSQVFQLAEMTLEERCAWEEMTTTHSSSSKSRRAKSSYFEQSFNWYWVDVTGRDASRQQYNAMLHYLTNRFKLCESFLVDREHTLVLPQVCESPIYAGQYLLNLRVATEKIAISDDSVMELTNRWIVVVDLKQHIVITLHRVDTHSMANLRSQWKRVIENSNVSFQEFLLKIIDDAIYTYHLSLDVHTALLEKCEAKLFVEKPAVTTPEVSGHYIDKQILHHFAGSSRSLFLRRLLDEQDRSPMDKGEMNSFLHHLHRRTSVQHRMINVTQAVLAKAFTKLRLCSREMAGQMCASCIEISDRALEVRDDAKTLLNLHISLQSFRTTELMAVLTRVTMLFTPVTFLAGVYGMNFQKNFPELTWDYGYPFFWALCIVLVIAMHVLFLRKH
Protein: Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor) (Q62463)
Organism: Mus musculus (Mouse)
Function: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Vasopressin-neurophysin 2-copeptin
- Oxytocin-neurophysin 1
- Guanine nucleotide-binding protein G
- VIP peptides
- Vasopressin V2 receptor
- Vasopressin V1b receptor
- Guanine nucleotide-binding protein subunit alpha-11
- Guanine nucleotide-binding protein subunit alpha-12
- Guanine nucleotide-binding protein subunit alpha-13
- Angiotensinogen
Sequence:
MSFPRGSHDLPAGNSSPWWPLTTEGANSSREAAGLGEGGSPPGDVRNEELAKLEVTVLAVIFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGPDWLCRVVKHLQVFAMFASSYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAASWGLSFVLSIPQYFIFSVIEFEVNNGTKAQDCWATFIPPWGTRAYVTWMTSGVFVVPVIILGTCYGFICYHIWRNVRGKTASRQSKGGKGSGEAAGPFHKGLLVTPCVSSVKSISRAKIRTVKMTFVIVSAYILCWTPFFIVQMWSVWDTNFVWTDSENPSTTITALLASLNSCCNPWIYMFFSGHLLQDCVQSFPCCQSIAQKFAKDDSDSMSRRQTSYSNNRSPTNSTGTWKDSPKSSKSIRFIPVST
Protein: Protein trichome birefringence-like 37 (O22960)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Plant UBX domain-containing protein 2
- Protein SOMBRERO
- ADP-ribosylation factor GTPase-activating protein
- BEL1-like homeodomain protein 4
Sequence:
MGFKLNSLFLLLSLLILTILSGADQALAYVKKPHVSQRNKTALAAVAGRGGGKEMLKGRKQTSGCNLFQGRWVFDASYPFYDSSTCPFIDGEFDCLKFGRPDKQFLKYSWQPDSCTVPRFDGEAFLKKWRGKRVMFVGDSLSLNMWESLACMIHSSVPNTKTTFLKRTPLSSLTFQEYDVTLFLYRTPYLVDISKESVGRVLNLGAIEDGADAWKNMDLLVFNSWHWWTHTGVQSQGWDFIRDGSSLMRDMDRLDAFNKGLTTWGQWVDQNVNVSQTRVFFQGISPTHYMGREWNEPRKTCNGQMQPLTGSTYPGGSLPAASIVSRVLSTMRTPVYLLDITTLSQLRKDAHPSTYGGDGGTDCSHWCLPGLPDTWNQLLYAALSM
Protein: Rifin (Q8I493)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKLHCSKILLFSLQLNILITSSYVNNKNKPYITPHTSAITSRVLNECDLYMPNYDKDADMKSVKENFDRQSSRRFEEYEERMITNRQKYKEQCEKDIQKIILKDKIEKLLEEKVEKCCLICGCGLGGGVAPFVGLFGGLAVNEMKKAAVVAATDVGIKEAIKEVGSIFYLADGSTMEWTKMINAGNYSQKMSLVEIVTILKNKCEEDEALAGPLFCKASEAATESGEVFEFSGNISRMAANAAEAAGNAANGKYAEMTSVGTICSNPVVISAIVVVIIAVILLIIYLILRYRRKKKMKQKQQYTKLLNQ
Protein: Protein A49 (P21068)
Organism: Vaccinia virus (strain Copenhagen) (VACV)
Interaction partners:
Sequence:
MDEAYYSGNLESVLGYVSDMHTELASISQLVIAKIETIDNDILNKDIVNFIMCRSNLDNPFISFLDTVYTIIDQENYQTELINSLDDNEIIDCIVNKFMSFYKDNLENIVDAIITLKYIMNNPDFKTTYAEVLGSRIADIDIKQVIRKNILQLSNDIRERYL
Protein: GM14851p (Q7K018)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
NNAFVEIAINNNNALLLLLQVAGGQGSRCGVEKRPQHMWHPALGGSVPEHQADGYQCHRSGQVPPHAERQELLHPWLRGAIRAAAGRRGGHPAAPGCGAKGGCCEHKIRIPLPAAQLDLPIAS
Protein: Melanoma-associated antigen 1 (Antigen MZ2-E) (Cancer/testis antigen 1.1) (CT1.1) (MAGE-1 antigen) (P43355)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- demerged
- G antigen 2A
- Cancer/testis antigen 1
- Heat shock 70 kDa protein 4
- Probable ATP-dependent RNA helicase DDX43
- E3 ubiquitin-protein ligase TRIM31
- SNW domain-containing protein 1
- Cancer/testis antigen 2
- Chondrosarcoma-associated gene 1 protein
- Melanoma-associated antigen 12
Sequence:
MSLEQRSLHCKPEEALEAQQEALGLVCVQAATSSSSPLVLGTLEEVPTAGSTDPPQSPQGASAFPTTINFTRQRQPSEGSSSREEEGPSTSCILESLFRAVITKKVADLVGFLLLKYRAREPVTKAEMLESVIKNYKHCFPEIFGKASESLQLVFGIDVKEADPTGHSYVLVTCLGLSYDGLLGDNQIMPKTGFLIIVLVMIAMEGGHAPEEEIWEELSVMEVYDGREHSAYGEPRKLLTQDLVQEKYLEYRQVPDSDPARYEFLWGPRALAETSYVKVLEYVIKVSARVRFFFPSLREAALREEEEGV
Protein: Transcriptional regulator, CarD family (Q2IDH2)
Organism: Anaeromyxobacter dehalogenans (strain 2CP-C)
Interaction partners:
- Peptidase zinc-dependent
- DNA-directed RNA polymerase subunit omega
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit beta'
- Glycosyltransferase RgtA/B/C/D-like domain-containing protein
- DUF4179 domain-containing protein
Sequence:
MRGPPARHPNDDAREQLPAPEGIIGIADELKPGDRVVYPNQGVCAVVGWEVKDIAGQKLELVRMTREEDGAAVMVPKGKVPSIGLRRVATGAQMEGVFHYLGAVYDDPELDWKIRHRDNADRLIAGGVLGVAEVVKGLHSLSRLRPLPTKEREQYDNARHLLVHEVSVSLAVPPGLAEDYIDYALMPPAGVKFDLKPPPAPVPLPSRPKKRRVVEEAEEGDLGLGDLGLGDLGIDLEGALEGAEVPGAEAEGAEGAEAGEGEAAGAEGVEAIPGVEEAAPEELPEAEEPVAEEEPEELPVRAPRAAKPARTAEKPGKVEKPEKAAEKKAARPAKPKKAEPEKPAKVEKHAEKPAARKAAAEKPAPAKKAAAKKPAAPKKAPAKKPAAEKPAAKRGGKKK
Protein: Cardiotrophin-like cytokine factor 1 (F8W2M3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- LIF receptor subunit alpha b
- Cytokine receptor-like factor 1
- Ciliary neurotrophic factor receptor
- Gp130 protein
- Prolactin receptor
- IL-6 subfamily cytokine M17.
Sequence:
MCPWKVGQVAVLLLLAVTVGNAQELDRTLILSNERSSIERTYELTKYLDHQLKEIRDTYLSYLGPPFSDPGFSPPRPNSSSLSVPSAATRVDLWRGLENGARLAQNQHAYSILLCAVRELARSTLCPYLQSSLLHFCSGLSGLLGSISGLMNALGYTNLPSSAGYATPAQGYAPAMSSQFQGVSENSPAPLRSYVPRNQGAKTVSGVREGTTRADLKRDREKERAERGRRGRRKEGESWVAKEEGEKEEGMERWGKRRRLLSMDEEKTIKLNNMNYTSLKFGDGYRKQPLLFSTPSLHPRRSVRSIPSSHSGLSPLSLLYQYGGPVSEVHTLLAAPVLSSHPTANDFSRKVEGFWVLRELQSWLWRSAKDFTRLKKRLRV
Protein: Bone morphogenetic protein 2 (C8C060)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
Protein: UDP-glucuronosyltransferase 2A1 (UDPGT 2A1) (UGT2A1) (EC 2.4.1.17) (UGT-OLF) (P36510)
Organism: Rattus norvegicus (Rat)
Function: UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (testosterones) and estrogens (estradiol and estriol). Contributes to bile acid (BA) detoxification by catalyzing the glucuronidation of BA substrates, which are natural detergents for dietary lipids absorption. Shows a high affinity to aliphatic odorants such as citronellol as well as olfactory tissue specificity, and therefore may be involved in olfaction.
Subcellular location: Membrane {ECO:0000250|UniProtKB:P0DTE4}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLKNILLWSLQLSLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSVSPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMTKLQRGKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFADRVRNFISYRMQDYMFETLWKQWDSYYSKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACMASAILLVIKCCLFVFQKIGKTXKKNKRD
Protein: Frizzled homolog 9 (Drosophila) (Q8TAN2)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MAVAPLRGALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENREKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKVGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITNGVWVWSSKTFQTWQSLCYRKIAAGRARAKACHAPGSYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL
Protein: Transmembrane emp24 domain-containing protein p24delta4 (Protein CYTOPLASMIC BODIES) (p24 family protein delta1b) (p24delta1b) (p24 family protein delta4) (p24delta4) (Q9FVU0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Required for trafficking GLL23, a component of the PYK10 complex. May act as a receptor facilitating its packing into COPII carriers and export from the endoplasmic reticulum.
Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Cycles between the endoplasmic reticulum and Golgi via COPI and COPII dependent pathways. Mainly located in endoplasmic reticulum.
Interaction partners:
- Transmembrane emp24 domain-containing protein p24beta2
- Transmembrane emp24 domain-containing protein p24beta3
- Protein kinase superfamily protein
- Coatomer subunit delta
- Disease resistance protein RPS6
- GPI inositol-deacylase
- GPI ethanolamine phosphate transferase 2
Sequence:
MKKKMIPTTILLSALIFSLSPICEAVWLTVPHTGSKCVSEEIQSNVIVLADYLVISEEHSIFPTVSVKVTAPYGTVLHHRENTTNGQFAFTTQESGTYLACFEADAKSHGNKDFSINIDWKTGIAAKDWDSIARKEKIEGVELEFKKLEGAVEAIHENLIYLRNREAEMRIVSEKTNSRVAWYSIMSLGICIVVSGLQILYLKQYFEKKKLI
Protein: Aromatic amino acid exporter YddG (P46136)
Organism: Escherichia coli (strain K12)
Function: Amino acid transporter with broad substrate specificity. Can transport various amino acids, including phenylalanine, tyrosine, tryptophan, L-threonine, L-methionine, L-lysine, L-glutamate, L-valine and L-isoleucine. Overexpression confers resistance to phenylalanine and increases export of phenylalanine, tyrosine and tryptophan.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:21042032}; Multi-pass membrane protein {ECO:0000269|PubMed:21042032}.
Interaction partners:
- Uncharacterized membrane protein YahN
- Leucine efflux protein
- Inner membrane protein YtfF
- Aromatic amino acid transport protein AroP
Sequence:
MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLWPSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMIFSTPVMIKLISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRRG
Protein: D-arabinono-1,4-lactone oxidase (ALO) (EC 1.1.3.37) (EC 1.1.3.8) (EC 1.3.3.12) (FAD-linked oxidoreductase ALO1) (L-galactono-gamma-lactone oxidase) (O93852)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: D-arabinono-1,4-lactone oxidase that catalyzes the final step of biosynthesis of D-erythroascorbic acid, an important antioxidant and one of the virulence factors enhancing the pathogenicity. Is also able to oxidize L-galactono-1,4-lactone, L-xylono-1,4-lactone and L-gulono-1,4-lactone.
Interaction partners:
Sequence:
MTDIPESLKPFVTKKVIHSTWAGTFLCKPQAIFQPRNVEEIQELIKQARLHGKTIMTVGSGHSPSDLTMTTEWLCNLDKFNHVLLEEPYYAPKSPTDDTPEIKFVDLTVEAGTRIFELNEYLKRNNLAIQNLGSISDQSIAGLISTGTHGSTQYHGLVSQQVVSVKFLNSAGELITCSSVDKPEYFRAILLSLGKIGIITHVTLRTCPKYTIKSKQEIINFETLLNNWDNLWLESEFIRIWWFPYTNKCVLWRANKSTDPLSDPRPSWYGTKLGRFFYESLLWVSVHLFPRLTPFVEKFVFGQQYGEVETLGKGDIAVQNSVEGLNMDCLFSQFVNEWSSPLNSGPEILTELKKIITDASQTGDFFVHAPIEVRCSNVTYSDEPFTDDKNQKSLYPSQEWLSNRSKTSAGPIPGNNLRPYLDNSPKLPYSKDGKITNDQLTLFINATMYRPFGTNVETHKWFQLFEDVMSKAGGKPHWAKNFIGLTQDEKYDKQQDLKTQLEFGGKPFYTMLGFKPVMQDWFGKDLVAFNKVRKETDPDGVFLSGKVWAERNGILLD
Protein: VQ motif-containing protein 10 (AtVQ10) (Tobacco rattle virus-induced protein variant 1) (Q8VYI5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May modulate WRKY transcription factor activities.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9M9F0}.
Interaction partners:
- WRKY transcription factor 8
- VQ motif-containing protein 29
- VQ motif-containing protein 22
- VQ motif-containing protein 8, chloroplastic
- VQ motif-containing protein 20
- VQ motif-containing protein 11
- VQ motif-containing protein 31
- Sigma factor binding protein 2, chloroplastic
- VQ motif-containing protein 9
- Sigma factor binding protein 1, chloroplastic
Sequence:
MSGRGKVKSEPMKVVFINTQYVETDARSFKTVVQELTGKNAIVAAGPFDSPSAFDGRCYDGGSKIGEDTRQLHGGGGGGGRMGTTTEFDRLFKEMPHMEELYKLWSEY
Protein: Glutamine-rich protein 2 (Q3V2A7)
Organism: Mus musculus (Mouse)
Function: Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility.
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:30683861}. Nucleus {ECO:0000269|PubMed:30683861}. Cytoplasm {ECO:0000269|PubMed:30683861}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:30683861}. Note=Localization varies during spermatozoa development. The protein is distributed in the nuclear membrane of the spermatogonia, in the nucleus of round spermatids, in the nucleus and cytoplasm of early elongating spermatids, in the cytoplasm of late elongating spermatids, and in the flagella of epididymal spermatozoa. {ECO:0000269|PubMed:30683861}.
Interaction partners:
- Cilia- and flagella-associated protein 44
- Cilia- and flagella-associated protein 43
- Transcriptional regulator QRICH1
- Tetratricopeptide repeat protein 21A
- Cilia- and flagella-associated protein 251
- Cilia- and flagella-associated protein 70
- Armadillo repeat-containing protein 2
- Cilia- and flagella-associated protein 69
- Tetratricopeptide repeat protein 29
- Fibrous sheath-interacting protein 2
Sequence:
MENSVSEASLYLQDQLDKLRTIIESMLGSSSTLLSMSITPHKSTACLVPGQIDPEATCPACSLDVSHQVSLLVQRYEQLQDMVSGLAASRPSKKAKLQGQDEELLGHVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIEVLYQGIERLDKEKANREHLEMEIDEKADKSALASKVSRIQFDATTEQLNHMMQELVAKMSGQEQDWQKLLDKLLAEMDSKLDRLELDPLKQMLEDRWKSLRQQLKERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETTVTGQVISVTPIISSMPGHRSVRPYTVFELEQIRQQSRNLKLGSSFPRVDMSQMERSVGRLHSMHSRMLMDMEKVQVHFGGSVKASSQMIRELLHTQCLSHPCYKRGADTADYSYSTVSRRCGGSHTLTYPYRRNRPQHLSPLEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILGKDAPGVTKHNKAKLQQLQQLQQLQQLQQLQQLQQAQHARPHAHRQPSLGNMISPPSRPQSAQMIADSKAVPSGQKKDRPVSSEGRLLQSNVSHSSIPTDIASLQGSQQGLNMHIDVPPGEGLEEPTRGPRSTAAH
Protein: Gallinacin-1 (Gal-1) (Beta-defensin 1) (P46156)
Organism: Gallus gallus (Chicken)
Function: Has bactericidal activity. Potent activity against E.coli ML-35, L.monocytogenes EGD and C.albicans.
Subcellular location: Secreted. Cytoplasmic granule.
Interaction partners:
- Gallinacin-2
- Gallinacin-6
- Gallinacin-3
- Gallinacin-4
- Gallinacin-7
- Gallinacin-8
- Gallinacin-5
- Gallinacin-14
- Gallinacin-9
- Gallinacin-10
Sequence:
MRIVYLLLPFILLLAQGAAGSSQALGRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIWG
Protein: Protein FAM83B (Q5T0W9)
Organism: Homo sapiens (Human)
Function: Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22886302}. Membrane {ECO:0000269|PubMed:22886302}.
Interaction partners:
- Casein kinase I isoform alpha
- Casein kinase I isoform epsilon
Sequence:
METSSMLSSLNDECKSDNYIEPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYILKNVQKVAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGVSVYILLDESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKALWENGTYQHSVSSLASVSSQRNLFGRQDKIHKLDSSYFKNRGIYTLNEHDKYNIRSHGYKPHFVPNFNGPNAIRQFQPNQINENWKRHSYAGEQPETVPYLLLNRALNRTNNPPGNWKKPSDSLSVASSSREGYVSHHNTPAQSFANRLAQRKTTNLADRNSNVRRSFNGTDNHIRFLQQRMPTLEHTTKSFLRNWRIESYLNDHSEATPDSNGSALGDRFEGYDNPENLKANALYTHSRLRSSLVFKPTLPEQKEVNSCTTGSSNSTIIGSQGSETPKEVPDTPTNVQHLTDKPLPESIPKLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIKSATMGNSYGRSSPLLNYNTGVYRSYQPNENKFRGFMQKFGNFIHKNK
Protein: Protein SMALL AUXIN UP-REGULATED RNA 51 (Q9LR00)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion (By similarity). Triggers plant growth probably by promoting cell elongation (By similarity). Regulates branch angles and bending (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9FJG1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9FJG1}.
Interaction partners:
- At3g12955
- Small ribosomal subunit protein mS81
- Probable E3 ubiquitin-protein ligase LUL1
Sequence:
MAMKKANKLTQTAMIKQILKRCSSLGKKQSNVYGEDENGSPLNVPKGHFVVYVGENRVRYVVPISFLTRPEFQLLLQQAEEEFGFDHDMGLTIPCEEVVFRSLTSMLR
Protein: Alpha/beta-Hydrolases superfamily protein (Putative lysophospholipase) (Q8L9X1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alpha/beta-Hydrolases superfamily protein
- Glycerophosphodiester phosphodiesterase GDPD1, chloroplastic
- Glycerophosphodiester phosphodiesterase GDPD6
- Glycerophosphodiester phosphodiesterase GDPD2
- Glycerophosphodiester phosphodiesterase GDPD5
- Glycerophosphodiester phosphodiesterase GDPD3
- Alpha/beta-Hydrolases superfamily protein
- Phospholipase A
- Lecithin-cholesterol acyltransferase-like 4
- Phospholipase A
Sequence:
MSISGAAVGSGRNLRRAVEFGKTHVVRPKGKHQATIVWLHGLGDNGSSWSQLLETLPLPNIKWICPTAPSQPISLFGGFPSTAWFDVVDINEDGPDDMEGLDVAAAHVANLLSNEPADIKLGVGGFSMGAATSLYSATCFALGKYGNGNPYPINLSAIIGLSGWLPCAKTLAGKLEEEQIKNRAASLPIVVCHGKADDVVPFKFGEKSSQALLSNGFKKVTFKPYSALGHHTIPQELDELCAWLTSTLSLEG