wanglab/gogpt-training-data huggingface dataset:
Protein: UDENN domain-containing protein (G5ECW9)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000256|ARBA:ARBA00004132}.
Interaction partners:
- Ras-related protein Rab-35
- Rab-GAP TBC domain-containing protein
- AP-2 complex subunit alpha
- Serine/threonine-protein kinase akt-2
- Serine/threonine-protein kinase akt-1
- Receptor-mediated endocytosis protein 6
- UDENN FLCN/SMCR8-type domain-containing protein.
Sequence:
MTYGRYRADVATLYDVFCELDAPKPGEKLAILRLQYPDDFHDPAIVKSVQQFAFPCQLREVEVDAVQLFSFVLTDSNSKFSFGFCRYTPRTDTCICFLSGFFWPNVFFKALNDISLVIGSAQREDVESVLTKFYHTDIPNIDEYLRFADSNQTDGHNYRVVFAEKIPDHTRLPTLGSDKFFLEFYNAIDPRQMLAIFASLLKERRILFTGRKVGSLSSCLHAVSMLLYPMCWQSVFITILPESLVDMVMAPMPYLIGVPKTVLENARLNIRDIGEVVIVDIDEKTLTSPFDDVAAMPQEVVNFLKAQLRSQSAMDDTFAKHFLRAMVMLFGDYTSGFTGDTPETLVFSKERFVVQQKPSYQAYVSSLLGADGVQYLERFIHDRLELYKDGHVPGDQFEIEIEQMDLKNRPVKENANDVIGALKTSGIQIANRLQKLTPREIRKAAARKKAHNQNGFEQSPMSFDNLQWDATKSDENEGFPVETRMDNVPVANLIDLDEPSTSSASGLTSVDEQYFLRPSELATNNRKSPSGAIGNVFADPFATSPEGSAPPLPSRPPPPLHPRMIPGSSVQSISPSGSSAPHLLHFQQSHQWAQVSQVGSVPSAMNPSAPDWYAPPPLPPRRPASVGPSSTSSGQPATAFATSSAIRVPPPPVRSKWETFE
Protein: Calnexin homolog (P36581)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Interaction partners:
- UDP-glucose:glycoprotein glucosyltransferase
- Glucosidase 2 subunit alpha
- Endoplasmic reticulum chaperone BiP
- Putative protein disulfide-isomerase C1F5.02
- Pre-mRNA-splicing factor cwf10
- Probable mannosyl-oligosaccharide glucosidase
- Glucosidase 2 subunit beta
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3
- Protein OS-9 homolog
- Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
Sequence:
MKYGKVSFLALLCSLYVRGSLADPESEQEPLVFNPTEVKAPLVEQFQGAWSERWIPSHAKRFVNGIEEMSYVGEWTVEESSGPGALKGEAGLVMKDEAAHHAISYEFDEPINEPEKDLVVQYEVNPEEGLNCGGAYLKLLAEPTHGEMSNSIDYRIMFGPDKCGVNDRVHFIFKHKNPLTGEYSEKHLDSRPASLLKPGITNLYTLIVKPDQTFEVRINGDVVRQGSLFYDFIPPVLPPVEIYDPEDIKPADWVDEPEIPDPNAVKPDDWDEDAPRMIPDPDAVKPEDWLEDEPLYIPDPEAQKPEDWDDEEDGDWIPSEIINPKCIEGAGCGEWKPPMIRNPNYRGPWSPPMIPNPEFIGEWYPRKIPNPDYFDDDHPSHFGPLYGVGFELWTMQPNIRFSNIYVGHSIEDAERLGNETFLPKLKAERELLSKQESMEKQSMHVDEESNQILEKFLDVYDIIKAKLPPNVAEKVDYYVETIIETPEIGIAIVAVLGSLTAVILTCYFYFFASSSPASLSTGTTEAEKEQQEKFKQETETEKIDVSYAPETESPTAKNED
Protein: Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Xanthine oxidoreductase) (Axorp) (XOR) (R4ZGN4)
Organism: Blastobotrys adeninivorans (Yeast) (Arxula adeninivorans)
Function: Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Oxidizes xanthine, hypoxanthine and pterine at high rates. Can also act on purine and guanine.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:23773263}.
Interaction partners:
Sequence:
MVDLQLHQSLGHHNFTNKLTFYVNGVKRTISNPDPRGTLLDFIRTHEGLTGTKLGCSEGGCGACTVVVASWDREQGEIIYSAVNSCIVPLVAVEGKHLITVEGIGSSNNPHPAQERIALFHGSQCGFCTPGIVMSLYALLRNTGGQPSKEQIAESFDGNLCRCTGYKPIIDAANTFSCGRPGGCCRDNASGKANGAGATVGNGMANGAAAVANGNGAAANGCCKGNGAANGCCKSNGSAATTANGDDKEVDMNKLFTPNGLPLKPYSAKTELIFPPALKKYELNPLFFGNEQKVWFRPVTKLQLLQIKHAYPESKIVGGASEIQIEIKMKAANYNISVYANDIEELKTHKYIPGKGLEFGANISLSKLEEVCDKLVHELDPNVSQIYGAILEQLKYFAGRQIRNAATPAGNIATASPISDLNPVLVAAEAVLTVESIENGEEQISMTDFFVGYRKTKLPAHGVITKIFVPETVPRNEVVMAYKQAKRKDDDIAIVTACLRLALDDDFRISKARLAYGGVGPFTTAAKGTAEFLTGKLLRRETAKEVLEGAIDCLIKEFDLPYSVPGGMAAYRRTLIMSFFYKFYSTVLEKIGLAGEAQDNSALENTYDPQALLEVTRKHPVGSRDLTNPYEQRIVGKSDPHLSALKQVTGEAVYIDDIPPYHGECFGVQVMSTKPRARILSVDPSPALEVEGVVGYVDVNDLPSREANIWGPTPVGKEPFFADGEVYYVGQCIGVIIATDRMIAEEAARLVKVEYEELETVITIEEAIEAQSFFDYQPKAEKGDVDGAFAESAYTFEGTSRIGSQEHFYLETQGSLVVPEPEDGEMKVYSSSQNPTETQVFVAQATGVPSSRIVARVKRLGGGFGGKESRCCHLSSIAAVAAKKYKRPVRMILSRSEDMLTAGQRHPFVMKWKVGLDKNYKFTALEAKLYANAGWSMDLTKGVIERAVLHAENCYDFPNARIQGIPCRTSVASNTAFRGFGGPQGMFMAECYIYEIADQLGIEPDTLREINYLVPGVSSTPFKQAITEDFTVPDMVKQIKKQSNYDDLRRQVEEFNSKHKWIKRGLAHVPTMFGISFGATFLNQAGALVHIYHDGSILLTHGGTEMGQGLHTKMAMVCAEELKVPLSQVFISETSTNTVPNTSASAASASSDLNGMAVKHACDQLNERLAPYRERLGENATMEQLAHAAYFDRVNLSANGFYKTPDIGFVWGDPNPKPAFFYFTQGCAVAMVEVNTLTGDWSNLRTDIVMDIGRPINQAIDYGQIEGAFVQGQGLFTIEESLWLRNGALFTRGPGAYKIPGFRDIPQEFNVGHLRDRPFKHLKTIHRSKGIGEPPLFLGSSVFFAIRDALSYARRQNLGEATMPAGLVAPMTTERIRMLAGDSLYEHKGKIEPTEGDDKPFFVNA
Protein: Noelin-2 (Olfactomedin-2) (Q568Y7)
Organism: Rattus norvegicus (Rat)
Function: Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization. Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling.
Subcellular location: Secreted {ECO:0000250|UniProtKB:O95897}. Synapse {ECO:0000305|PubMed:22632720}. Membrane {ECO:0000250|UniProtKB:Q8BM13}. Nucleus {ECO:0000250|UniProtKB:O95897}. Cytoplasm {ECO:0000250|UniProtKB:O95897}. Note=Nuclear localization is induced by TGF-beta. {ECO:0000250|UniProtKB:O95897}.
Interaction partners:
- Glutamate receptor 1
- Protein cornichon homolog 2
- Protein cornichon homolog 3
- Glutamate receptor 4
- Noelin
- Glutamate receptor 3
- Leucine-rich repeat transmembrane neuronal protein 4
- Noelin-3
- Glutamate receptor 2
- Voltage-dependent calcium channel gamma-3 subunit
Sequence:
MSVPLLKIGAVLSTMAMVTNWMSQTLPSLVGLNSTVSRAGSSEKITLFQSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCARDGRSRELRQLMEKVQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRTADGSVSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGNLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITIRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVVRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTAGDP
Protein: Dolichyl-phosphate-mannose--protein mannosyltransferase (EC 2.4.1.109) (Q6FUT7)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367007}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367007}.
Interaction partners:
Sequence:
MDSELRARKAPSVSEVKVEHDHGHDLANDNKEQKASNKQFWLRLERVAMPIVFTLLALLVRLYRLDVVKKVTWDEAHFGKFGSYYLRHTFYHDVHPPLGKMLVGFSGYLAGYNGSWDFPSGQPYPDYVPFVKMRIFQGAVSALCVPMTYFAAKAIGFSLPTVWLTTILVLCENSYTTLGKLILLDSLLLFFTVATFMCFQKFHSYHRKPFSFQWCLWLFLTGASMGCAISVKMVGLFVITLVGIHTIVELWTLLGDKNITWKRYANHWIARIICLIVTPFLIFALCFKIHFALLWGSGPGDHEMPPRFQAALNGTNIGQGPRDVSIGSTITLQNMKPRGAYLHSHHQTYPEGSKQRQVTCYNYVDGNNDWIVYRPHGKPIWHVNDTEHEAIRNGDTIRLVHKGTGSNLHSHQVEAPLNKLDYEVSGYGNLTIGDLKDHWVVEIIKDDGNEDKNLIHPITTHVRFRHAVLNCYLAQSNEHLPEWGFSQAEVRCIREPEKNDIKTMWIVDTHTHPNLEAPENFIYPRRSFWSDFFELNKRMMATNNALTVSKDKHDYLRSESWEWPTLYRSLRINSWNENDTRYLLLGSPASTWPSTVAVLFLVFALLYKVLKWNRQMQIFQNEHDEELFIYGGVYPLLGWFLHFFPFVIMGRVKYVHHYLPALYFALFVLAYIFDAGLRYYNKTKTQRIIKFCIYAGYMSVVIGGFILFAPFSYGMTGKLENYKHLNWMKNWDVV
Protein: Lactoperoxidase (LPO) (EC 1.11.1.7) (A0A452E9Y6)
Organism: Capra hircus (Goat)
Function: Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2) (By similarity). Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2 (By similarity). Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism. Shows antibacterial properties against several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species. Inhibits the growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor. Does not have anti-fungal activity towards C.albicans and Pythium species. May protect the udder from infection and may promote growth in newborns. May be implicated in airway host defense against infection (By similarity). May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:18191143, ECO:0000269|PubMed:27398304, ECO:0000269|PubMed:30296068}. Cytoplasm {ECO:0000250|UniProtKB:Q5SW46}.
Interaction partners:
- Lactotransferrin
- Alpha-lactalbumin
- Beta-lactoglobulin
- Kappa-casein
Sequence:
MLVCLHLQVFLASVALFEVAASDTIAQAASTTTISDAVSKVKTQVNKAFLDSRTRLKTALSSEAPTTRQLSEYFKHAKGRTRTAIRNGQVWEESLKRLRRDTTLTNVTDPSLDLTALSWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQNKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKILAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHVTKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN
Protein: Apicoplast TIC22 protein (Q8I3H4)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Plastid, chloroplast {ECO:0000256|ARBA:ARBA00004229}.
Interaction partners:
Sequence:
MCLLLFICLYFARGIYCLKTLNGLSRDINNSIYLRNNVHKKKRLVDCNLCMLKHKFRLSFWKKRYDERPIEEKLEVIPVFLITNYNSSPYIFQENEKQVCYMFLCPYDAENMLNDMIKYNGMKYNGNIKIHNITMKKAYELMKEFLQLEKMEVNKEDSKKKQNIYWKLISSKRQLQNALYYLSFTKKSELMYPVFYAENLYIQKDGSNIIPLFFDLEDLKEAIEEQKNKALSKVDYKIKVLNMVDLIFTEDHKKFGFVPSTQSVKYLDKLNIGTKKTYF
Protein: 14-3-3-like protein GF14-F (14-3-3-like protein S94) (G-box factor 14-3-3 homolog F) (OsGF14a) (Stress-regulated 14-3-3 protein) (SR14-3-3) (Q06967)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- HECT-type E3 ubiquitin transferase
- Os03g0311300 protein
- F-box domain containing protein
- Arsenate reductase 2.1
- F-box domain containing protein, expressed
- Arsenate reductase 2.2
- Os12g0463700 protein
- Os05g0483801 protein
Sequence:
MSPAEASREENVYMAKLAEQAERYEEMVEFMEKVAKTTDVGELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEAYVASIKEYRSRIETELSKICDGILKLLDSHLVPSATAAESKVFYLKMKGDYHRYLAEFKSGAERKEAAENTLVAYKSAQDIALADLPTTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDDAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDNAEDGGDEIKEAAKPEGEGH
Protein: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) (Q2HQK2)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEELHDAYPTVNFIPGKPTQSSGIVQALNTLDSTIKVNAVHKGDTAFGMQVYSAIQKIPKGETRSYSDIAREIGNPSAVRAVASACARNNLAYIVPCHRVIGSTGNLSGYRWGIAKKRRLLQAEGAELRFSVM
Protein: Peroxidase 39 (Atperox P39) (EC 1.11.1.7) (ATP19a) (Q9SUT2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000255|PROSITE-ProRule:PRU00297}.
Interaction partners:
- Transcription factor UPBEAT1
Sequence:
MTRFGLALLMILVIQGLVTFSEAQLKMGFYDQTCPYAEKIVQDVVNQHINNAPSLAAGLIRMHFHDCFVRGCDGSILINATSSNQQVEKLAPPNLTVRGFDFIDKVKSALESKCPGIVSCADIITLATRDSIVAIGGPTWNVPTGRRDGRISNFAEAMNNIPPPFGNFTTLITLFGNQGLDVKDLVLLSGAHTIGVSHCSSFSNRLFNFTGVGDQDPSLDSEYADNLKSRRCLSIADNTTKVEMDPGSRNTFDLSYYRLVLKRRGLFESDAALTMNPAALAQVKRFAGGSEQEFFAEFSNSMEKMGRIGVKTGSDGEIRRTCAFVN
Protein: RB binding protein 6, ubiquitin ligase (A0A2R8Y880)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAGRLLFHKLGTMGHKQIDTYFWNRGDVYGATATQITHLREAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSA
Protein: Integrin subunit alpha D (A0A8I6A686)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Interaction partners:
Sequence:
MTLKFLLVTVLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQTGALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVVTSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLGQRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLNCSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ
Protein: Large ribosomal subunit protein eL36B (60S ribosomal protein L36-B) (O94658)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL8
- Large ribosomal subunit protein eL18A
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL6
Sequence:
MAPGLVVGLNKGKTLTKRQLPERPSRRKGHLSKRTAFVRSIVREVAGFAPYERRVMELIRNSQDKRARKLAKKRLGTLKRAKGKIEELTSVIQSSRLAH
Protein: P2X purinoceptor (B0R182)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU000681}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU000681}.
Interaction partners:
- Intermediate conductance calcium-activated potassium channel protein 4
Sequence:
MAQTWGNFFFSLLDYKTEKFVIAKNKKVGVLFRLFQLTVIGYLIGWVFIWKKGYQETEEAIQSSVITKLKGVDLTNSSQFGLQLWGAEDYVIPPQGDRVFFVVTNYLVTPNQRLGYCPESPKVPDGFCTNDNECVEGESVLAGHGVKTGRCLNDTGTCEINAWCPVEHGHAPVEPMLAKAENFTVYVKNFIKFPKFGFFKSNVLPITNSTYLKTCRYDKDHHPYCPIFLVGDVINWTGYTFQDLATRGGSIGIGIEWNCDLDKDESHCNPEYSFTRLDSSENSQHSVTSGYNFRFARYYNDAAGQTYRNLFKVYGIRFDILVNGKAGRFSIIPTVINIGSGLALMGAGVFACDMILLYMMSKSSFYRETKFEAIKKKQSERESREQRERKHARHHRHHHHHRQDGRHRREEKPTAEMQPLTSILTQANNNPETQTQPSAASALKPHSPERKPQATVSFRTHTTEKHTVSPVSTLRAARHQ
Protein: peptide-methionine (S)-S-oxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Q9XHG1)
Organism: Gracilaria gracilis (Red alga)
Interaction partners:
Sequence:
MGNVTRKAAVQNGKSKAATLVDEAIQTNPVVIFSKTYCPYCQSAKSNIRSALKKIANAPKPEIFELDRMGSLGYQIQNYLAQVTGRHTVPNVFIGGSSVGGGDDIAAYARRGVLVQMLTQAPQRLVHQFPERFEPEKKPDTAAEAVERAIKDNAVMVFSKSYCPFCTSAKDLLQERIAAVEGLNPINVFELDEMGTDGAAMQQYLFQKTGQRTVPNIFIAGKHVGGSDDVHGLDARNELIPMLTSAAASVSSPAATEVLSAEEEQTETDTALPADVVSEEKPKTETKEIVFGAGCFWGVELAFQRVAGVLKTEVGYSNGKMSRVTYDAICTGATGSAEVVRVWYDPSVLFLKQLLEVWESRHDPTSLNKQGNDQGTQYRSAIYYSDEEQAEEVRRWISEASTRHTKEIVTEVAAIKNYCAAEEYHQRYLEKKGQSAEKGSSASIRCYG
Protein: G-protein coupled receptors family 1 profile domain-containing protein (A0A060Y1K1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Ig-like domain-containing protein
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
- Endothelin-3
- Neuropeptide Y
- Endothelin-1
- Endothelin-1
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
Sequence:
MDVAKFITVTYNTLQDANTSSAPRPLPHTELGSALIILLVTMIILVTIVGNVLVIVAVLTSRALRAPQNLFLVSLACADILVATLVIPFSLANEVMGYWYFGSPWCAFYLALDVLFCTSSIVHLCAISLDRYWSVTKAVSYNLKRTPKRIKSMIAMVWVISAVISFPPLIMTKHDEHECLLNNETWYILSSCLVSFFAPGLIMILVYCKIYKVAKQRSSTVKERMEIESPSSQSSEDHHRQEELDDIDLEESCCASDKPRNHRFSKRMKSCRLSWASAPQRQHLAVASSKTKVAQMREKRFTFVLAVVMGVFVLCWFPFFFTYSLHAICRESCYIPGALFNTFFWIGYCNSSVNPIIYTIFNRDFRKAFKKITHLLKHSAPVPISRSGLKLHHVVYLRRPRTFNI
Protein: Mitochondrial assembly of ribosomal large subunit protein 1 (Q96EH3)
Organism: Homo sapiens (Human)
Function: Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. May function as a ribosomal silencing factor (Probable).
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:16548050, ECO:0000269|PubMed:22238375, ECO:0000269|PubMed:22238376, ECO:0000269|PubMed:22829778, ECO:0000269|PubMed:23171548, ECO:0000305|PubMed:28892042}. Note=Colocalizes with MRPL12 and/or MRPL14. {ECO:0000269|PubMed:22238375, ECO:0000269|PubMed:22829778}.
Interaction partners:
- Large ribosomal subunit protein bL19m
- Mitochondrial ribosome-associated GTPase 1
- rRNA methyltransferase 3, mitochondrial
- Large ribosomal subunit protein bL32m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL20m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL11m
Sequence:
MGPGGRVARLLAPLMWRRAVSSVAGSAVGAEPGLRLLAVQRLPVGAAFCRACQTPNFVRGLHSEPGLEERAEGTVNEGRPESDAADHTGPKFDIDMMVSLLRQENARDICVIQVPPEMRYTDYFVIVSGTSTRHLHAMAFYVVKMYKHLKCKRDPHVKIEGKDTDDWLCVDFGSMVIHLMLPETREIYELEKLWTLRSYDDQLAQIAPETVPEDFILGIEDDTSSVTPVELKCE
Protein: Pancreas/duodenum homeobox protein 1 (Q6DC85)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MNREEHYYPPNHLYKDSCAFQRHPNEDYSQNPPPCLYMRQAHSVYASPLGAQDQPNLTDITSYNMSSRDDLAGPHLHLPQTSQTSLQSLGGYGDSLDLCGDRNRYHLPFPWMKSTKSHTHAWKGQWTGPYMVEAEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELALTLSLTERHIKIWFQNRRMKWKKEEDKRRARGVDPEQDSSITSGDLKDESCVGTATLAGPPSPLHPHAPSVQQDS
Protein: Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (Q09413)
Organism: Caenorhabditis elegans
Function: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q63187}.
Interaction partners:
- Elongin-C
- Elongin-C
- RNA polymerase II transcription factor SIII p18 subunit
- Cullin-5
- Elongin-C
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein uL3
Sequence:
MPETDEEKVRRYTECLMNGIDPKRALKRLYDLNVSPEVFKSADTYQCVKRYESSPELAKYAKRVRDKLLGGRKREKGGGEDDADIEHTALKKAKKEEVNLDEEFAEAMKSGVSAQASSAPRATVDYSKYKVVKRVEVKVEPKPEPVDVHEQQASSSSMSYQREHQKDYAPVVPTCKPSGQPKKAIPQSKSLHADENMFKPRKERQKVFAGRRKRVGEGVSTLVSLCQTVLMSHIDMIDHVGIVPFDLLKPVLDHASTDQLRHILDVNPMLVEDADEMFHEMVSREFPKYANREKSGWTWREMYDRLVEKKQKKENDKLEMLTSRIGKSNSAQSQGRQTMVIDMAHTRVRSKSFFNTVKDSQVKMSATPSALQLSQARKNVKIEGKAQLRTITPRGGGVPSTSRSRSNNNNNMNNGLVVKKTAPLMAKCKKMLKR
Protein: Neuronal acetylcholine receptor subunit alpha-7a (Nicotinic acetylcholine receptor alpha 7 subunit) (Q800C7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MGIWEYTLYFTTTCCLWSVSLQGEHQRRLYRDLMKDYNPLERPVFNDTHSLTVYFSMSLMQIMDVDEKNQVLTTNIWLQLYWYDYYLQWNASEYPGVTNVRFPDSQIWKPDILLYNSADERFDATFHTNVLVNSSGACQYLPPGIFKSTCYIDVRWFPFDLQRCDLKFGSWTYGGWSLDLQMIDADITGYIANGEWDLVEVPGRRNERFYDCCKEPYPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPEGGKMPKWTRVVLLNWCAWFLRMKRPGEDKVRPACHNKQPRSSLSSVDLNISPGVAQSTNGNLLYIGFRGMDTIHYATSPDSGVICSRLVATGEEDVLLPGAQASSVSSSGPGETELSKILDEVRYISKRFRDQDEEDTVCNEWKFAASVIDRLCLMAFSLFTILCTIGILMSAPNFVEAISKDFFT