wanglab/gogpt-training-data huggingface dataset:
Protein: Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (O45623)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MQCSPDPEDLLIVPTHDIPSYDESLDPFGPEGHLSLDIDCFSKFMSRSDNRIMSKPIIVRGIPWRILAICRNQQGSRHSMNSRVNRSNFNFGFFLQCNNDELLQKRGMWRCYGTAVLEVLNADGPSIQKKIHHSFHNTEVDWGFSNYDQYDTLCNPKDGYVVNDTIKLRCRFTADVPTGANYMWDSKRHTGCIGLRNQGATCYMNSILQSFYFTTGFRRAVYNMDVGTEPNESNIVLAMQRVFYELQMASEAVETNSLTRAFGWDKLDAFNQHDVQEFCRVLLDNLETKMKGTSEEKSIPNLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFEAYTTSEILDDENKYDAGDHGLQRAEKGVKFVELPPILHVQLMRFQYCGVEQKINERFSFPEKMNLASCCELGPMLTEEDCVYSLHAVLVHSGEFHGGHYVTYINVNLHESAVDPTSSAKWCKFDDDVVSRTTTDDAIVSNFGGEKTMNSSAYMLVYVRDNAIDQFLAPIPDSQIPQSVSRTFEMERLHRNREKKKLEEEQLCMGIVLVTPDIVASNHSFDLVDQSIVHDSIPHETVWKHMFTAELYQFVHDRLFEKSAMQKIDMFDSDDEARQARRDNLRRIKSKKFNFRLWRMTDSYSLERTTQKLTSRLRPSEFIDCKTDTRLDTLLSQDFETIYVEFSNNIERPLCEYDTARDLLFFVKYYDTMTDKFTIIGHTMFDCHKRFNLYRSMLCEMIGLPADTELKYYMEHAASYLELVDLTQNYSIGRLVEEQDGGILVVEKVETSTSTQNAKQKMNELFLDVEVEFVQSFYNKKPEEEPFEQFVKRICLDDKLFTVAEEIGARLNVDPKKVLIWTRVSGSRFEPFFDDYMLNTCKGLMTRPVHDPRAYKRYRVQYAIMPFDIDEISKHRIQTKLFWQLPNGHVEELTLFPLKEGTVIDIINEAKRYYPFVEGGSGKFRLLQIGAPPLSNQRVYQIYGENTLISDLDQRTMYKLVSSQALHCRLEEVPIDELDMSPGEFLCPVVHFDREPTKLFGLSFVIKIRNNELMTEVRDRLRRKLNDVSDADFAKYKFALLSRDKLCRTIEFNNGEKVNLADMANQTTGVPQVYIGLDHKSPIQHSSEAAIRILN
Protein: Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1) (Q9ERT9)
Organism: Mus musculus (Mouse)
Function: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Protein phosphatase 3 catalytic subunit alpha
- Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
- Calcineurin subunit B type 1
- cAMP-dependent protein kinase catalytic subunit beta
- Protein kinase C alpha type
- cAMP-dependent protein kinase catalytic subunit alpha
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Sequence:
MEPDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNSLLKSTLSMSPRQRKKMTRTTPTMKELQTMVEHHLGQQKQGEEPEGATESTGNQESCPPGIPDTGSASRPDTPGTAQKSAESNPKTQEQCGVEPRTEDSSAHMLPLDSQGASLV
Protein: Phosphoenolpyruvate carboxylase (PEPC) (PEPCase) (EC 4.1.1.31) (Q8XLE8)
Organism: Clostridium perfringens (strain 13 / Type A)
Function: Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Interaction partners:
- Pyruvate kinase
- Pyruvate, phosphate dikinase
- Pyruvate kinase
- Enolase
- Pyruvate kinase
Sequence:
MKIPCSMMTQHPDNVETYISIQQEPAEAIKGLTPQDKGGLGIEEVMIDFEGKLTPYHQTSQIALGLISNGIIPGKDVRVTPRIPNANKESVFRQLMSIMSIIETNVQSKELTGTPAISEVVVPMIETGKEISEFQDRVNSVVDMGNKNYKTKLDLNSVRIIPLVEDVPALANIDRILDEHYEIEKSKGHILKDLRIMIARSDTAMSYGLISGVLSVLMAVDGAYKWGEKHGVTISPILGCGSLPFRGHFSEENIDEILATYSGIKTFTFQSALRYDHGEEATKHAVRELKEKIAQSKPRNFSEEDKDLMKEFIGICSKHYLQTFLKVIDTVSFVSDFIPKNRDRLTKAKTGLEYNREVANLDNVADLVKDEVLKQEILSIDNSKEYAVPRAISFTGAMYTLGMPPELMGMGRALNEIKTKYGQEGIDKLLEIYPILRKDLAFAARFANGGVSKKIIDEEARQEYKEDMKYVNEILNLGLDYDFLNENEFYHTLLKTTKPIIMHLMGLEENVMRNSTEELKILNEWIVRMGKVRGSIG
Protein: Aldo-keto reductase family 1 member B10 (A0A8I5ZY17)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MATFVELSTKAKMPIVGLGTWKSTPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVRREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGFQAGKELFPKDEQGNVLPSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPRAKPDDPSLLQDPKIKEIAAKHKKTTAQVLIRFHIQRNVVVIPKSVTPARIQENIQVFDFQLSDQEMATILSFNRNWRACLLPE
Protein: H-2 class II histocompatibility antigen, E-B beta chain (P04230)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- H-2 class II histocompatibility antigen, A beta chain
- H-2 class II histocompatibility antigen gamma chain
- H-2 class II histocompatibility antigen, A-B alpha chain
- Class II histocompatibility antigen, M alpha chain
- Class II histocompatibility antigen, M beta 1 chain
- H2-O alpha
- T-cell surface glycoprotein CD4
- H2-M beta 2
- T-cell surface glycoprotein CD3 zeta chain
- Histocompatibility 2, Q region locus 2
Sequence:
MVWLPRVPCVAAVILLLTVLSPPMALVRDSRPWFLEYCKSECHFYNGTQRVRLLERYFYNLEENLRFDSDVGEFHAVTELGRPDAENWNSQPEFLEQKRAEVDTVCRHNYEISDKFLVRRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLGAGLFIYFRNQKGQSGLQPTGLLS
Protein: SNF1 protein kinase subunit beta-3 (Glucose repression protein GAL83) (Protein SPM1) (Q04739)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Beta subunit of the SNF1 kinase complex, which is required for transcriptional, metabolic, and developmental adaptations in response to glucose limitation. Has a structural role, mediating heterotrimer formation, and a regulatory role, defining carbon source-regulated subcellular location and substrate specificity of the SNF1 kinase complex. Promotes the relocalization of the SNF1 kinase complex to the nucleus upon shift to nonfermentable carbon sources.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11331606}. Nucleus {ECO:0000269|PubMed:11331606}. Note=Resides in the cytosol during growth on fermentable carbon sources and relocalizes rapidly to the nucleus in response to carbon stress. {ECO:0000269|PubMed:11331606}.
Interaction partners:
- Carbon catabolite-derepressing protein kinase
- 5'-AMP-activated protein kinase subunit gamma
- SNF1 protein kinase subunit beta-1
- SNF1 protein kinase subunit beta-2
- SNF1-activating kinase 1
- Protein SIP4
- Regulatory protein MIG1
- Regulatory protein CAT8
- Serine/threonine-protein kinase TOS3
- Resistance to glucose repression protein 1
Sequence:
MAGDNPENKDASMLDVSDAASNTTINGKHSADSTNEASLAYTFSQMNVDNPNELEPQHPLRHKSSLIFNDDDDDEIPPYSNHAENGSGETFDSDDDIDASSSSSIDSNEGDIHDADMTGNTLQKMDYQPSQQPDSLQNQGFQQQQEQQQGTVEGKKGRAMMFPVDITWQQGGNKVYVTGSFTGWRKMIGLVPVPGQPGLMHVKLQLPPGTHRFRFIVDNELRFSDYLPTATDQMGNFVNYMEVSAPPDWGNEPQQHLAEKKANHVDDSKLSKRPMSARSRIALEIEKEPDDMGDGYTRFHDETPAKPNLEYTQDIPAVFTDPNVMEQYYLTLDQQQNNHQNMAWLTPPQLPPHLENVILNSYSNAQTDNTSGALPIPNHVILNHLATSSIKHNTLCVASIVRYKQKYVTQILYTPLQ
Protein: Alpha/beta hydrolase related protein (Q8L7D8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein yippee-like At3g55890
- anthranilate synthase
- Embryo-specific protein ATS3B
- Embryo-specific protein 3
- Transcription factor VIP1
Sequence:
MGLISKEEISKTRRYSSSLWRGIKTIFVLFTMFLSFIIFSAPIFLAVADAVLPSAILSSSSPSLNRLSPSSFPATIYSYLSNYDFRYSLIDIPLISIIRSAIILCVYGLCDGPKLSRGPYLTITMICSISSLIYVSFKAAIVFGEPVIGGYFRTEEMALFLCSWILAIGHIVVAYRTSCRERRKLLVFKIDIESVSACKNVFPRYQKILQQERLK
Protein: Histone deacetylase 4 (EC 3.5.1.98) (CeHDA-7) (Histone deacetylase 7) (O17323)
Organism: Caenorhabditis elegans
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (By similarity). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Involved in transduction of sensory signals, together with egl-4, kin-29 and mef-2; binding to transcription factor mef-2 enables negative modulation of chemoreceptor gene expression in chemosensory neurons. May be involved in muscle development (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- MEF2 transcription factor homolog
- Serine/threonine-protein kinase kin-29
- Histone acetyltransferase
- Putative histone deacetylase 2
- Mortality factor related protein 1
- Histone deacetylase
- DNA polymerase
- DUF19 domain-containing protein
Sequence:
MEEASSSTGSAGGAGPSVPNLPSTSEAAIGQTNLEPESIALLQSQLQEYRQKQMDLIGHFQRAQQELSVQHMHNLYAALQQQQQLQNLQTERSAVNPLLISQQHSTEDQNSGPAAPLSLANSLTNLLSSSNGNLSVPQTPTKEHHPTAPTSNRKCDLPRSNSTTISQLTKDRLKNMIANRSKGESNSQSNLMSNSVTANGNGHDNGRKLKNSNSQVNVSSPHFEPYRLPTSLANAHNLQQASEFQLRKVNSEPNLKMRIRAKLLSKGSSPVQHVQQNNSQFNFTHPQLKRSDSETSQNVPLDFMQSSSQTNLPHLMLPSPSLPNLAAAGAFHGLNLPVGQDLNAFMAVANLSPFLSLPSLLNKKLELGGLTDEGDRNGLIGSSSTSSLASNVSMGSHQYQSLLKQQIRDLVLRRKSLVREDPEGEGLAELYNGLLPQAKLQQLQALAAESGFLAKQEPTCTTGLGYDQAMVRHECCCGNNASHVENGGRIQSIWSKLIEHGHVQKCEKVTAKKASLEQLQLVHSQTYTTFFAVSPTACLKIDANSLPLKRFLQLPCGGIGVDSDTYFNDASTQTAARLAAGTLIELSSQVAEGRLKNGFACIRPPGHHAEHEQAMGFCFFNNVAVAVKVLQTKYPAQCAKIAIIDWDVHHGNGTQLSFENDPNVLYMSLHRHDKGNFFPGTGSVTEVGKNDAKGLTVNVPFSGDVMRDPEYLAAWRTVIEPVMASFCPDFIIVSAGFDACHGHPNALGGYEVTPEMFGYMTKSLLNYASGKVVLALEGGYDLKSISEAAQQCVQALIGESDDAGRLSSVALESLPNPSAVETLQKVIAIHKSYWPALHGQEAAINTTEMQWRNLKLQVQMQQQQQQQQT
Protein: GATA transcription factor 14 (Q9M1U2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- GATA transcription factor 24
- Probable ADP-ribosylation factor GTPase-activating protein AGD15
Sequence:
MSGREDEEEDLGTAMQKIPIPVNVFDKEPMDLDTVFGFADGVREIIEDSNLLLEESREFDTNDSKPSRNFSNLPTATRGRLHAPKRSGNKRGRQKRLSFKSPSDLFDSKFGITDKSCSHCGTRKTPLWREGPRGAGTLCNACGMRYRTGRLLPEYRPASSPDFKPNVHSNFHRKVMEIRRERKSSPPNSFGFSESYHSTRKLGF
Protein: Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) (Q27960)
Organism: Bos taurus (Bovine)
Function: Involved in actively transporting phosphate into cells via Na(+) cotransport.
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:Q9DBP0}; Multi-pass membrane protein {ECO:0000255}. Note=Localized at the brush border membranes of enterocytes. {ECO:0000250|UniProtKB:Q9DBP0}.
Interaction partners:
- Na
- Solute carrier family 34 member 3.
- Tyrosine-protein kinase receptor
- Pulmonary surfactant-associated protein B
Sequence:
MAPWPELENSQPTSEKYTVKADGEQSAKPEKAKETEKDDTGTPITKIELVPSHSTATLIEEPTEVEDPWDLPELKDTGLKWSERDTKGKILCVFQGIGKFILLLVFLYFFVCSLDVLSSAFQLVGGKVAGKFFNNNSIMSNPLAGMVIGVLVTVLVQSSSTSTSIVVSMVASSLLPVHAAIPIIMGANIGTSITNTIVALMQAGDRKEFRRAFAGATVHDFFNWLSVLVLLPLEAATGYLERLTNLVVESFHFKNGEEAPELLKVITDPFTKLIIQLDKSILNQIAMNDESVQNKSMIKIWCKTFTNVTERNVTVPSPENCTSPSLCWTDGLYTWTIKNVTYKENIAKCQHIFVNFNLSDAIVGTILLITSLLILCTCLILIVKLLGSVLRGQVAAVIKKTINTDFPYPFSWVTGYLAILVGAGMTFIVQSSSVFTSAMTPLIGIGVISIQRAYPLTLGANIGTTTTAILAALASPGSTLKSSLQIALCHFFFNISGIILWYPIPFTRLPIRLAKGLGNISSKYRWFAIVYLIVFFLLIPLAVFGLSLIGWPVLVGVASPIVLVILLVVVLKILQSFCPGSLPQKLRSWDFLPFWMRSLEPWDKLITSLTSCFQMRCCCCCRVCCRLCCGLCGCSKCCRCTKCSEDLEEGKDEPVKSPEAFNNLAMDKEAQDGVTKSEVDASGTKIVSSVTAL
Protein: 60S ribosomal protein L26, putative (Q57YL9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Ribosomal protein
- 60S ribosomal protein L19, putative
- 60S ribosomal protein L5, putative
- 60S ribosomal protein L27, putative
- 60S ribosomal protein L35, putative
- 60S ribosomal protein L17, putative
- 60S acidic ribosomal protein P0
- 40S ribosomal protein S24
- 60S ribosomal protein L6, putative
Sequence:
MVGIKCRNRRKARRAHFQAPSHVRRILMSAPLSKELRAKYNVRSMPVRKDDEVRVKRGKFKGREGRVTACYRLKWVIHIDKVSCEKANGTTVPVGVHTSNVEITKLKLNTRRKAILERKDRSTKADKSKGKVTAAEKAMQQMD
Protein: RNA exonuclease 4 (EC 3.1.-.-) (O94375)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Ribosome biogenesis protein NOP53
- Probable oligoribonuclease
- tRNA
- Brix domain-containing protein C1B9.03c
- Probable mannosyl-oligosaccharide glucosidase
- tRNA
- Putative holocytochrome-c1 synthase
- Pre-rRNA-processing protein crb3/ipi3
- Pre-mRNA-splicing factor cwf7
- 3'-5' exonuclease eri1
Sequence:
MSSSNWEKLKKKLDSAKSGRVEKKHSNEKKYLKSVKGKNNENENSYIVDKKRMNELKKFAKENDIPESQVLDAYGVDASKLTRKTNLETLGKYIAMDCEMVGVADDMSVLARVSIVNYHGHVVYDTYVRPKEKVTDWRTWVSGVKSFHMRDAPSFEKVQAEVAKILDNRVLVGHAVHNDLKVLLLSHPRRMIRDTSRFSGYRKLAKGRTPGLKKLAEVILGRDIQSGQHSSVQDAQATMELYKKVKKEMDEVAFKGLSKS
Protein: Collagen, type VI, alpha 3 (D3YWD1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MRKHRHLPLVAVFSLLLSGIATTHAQQHGDVKNGAAADIVFLVDSSWSAGKDRFLLVQEFLSDVVESLAVGDNDFHFALVRLNGNPHTEFLLNTYHSKQEVLSHIVNMSYIGGSNQTGKGLEYVIHSHLTEASGSRAADGVPQVIIVLTDGQSEDGFALPSAELKSADVNVFAVGVEGADERALGEVASEPLSMHVFNLENVTSLHGLVGNLVSCIHSSVNPERAGDKESLKDITAQDSADIIFLIDGSQNTGNANFDVIRDFLVNVLERLSVGNQQVQVGVVQYSEEPITMFSLNSYPSKAAVLDAVKGLSLVGGESANIGQALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRDSVVALKQASVFSFGLGAQAASRAELQHIATDDSLVFTVPEFRSFGDLQEQILPYLVGVAQRHIVLQPPAIVTQVMEVNKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVKPEFYLNSYTNKRDAITAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDEVSQPAQELKRGSIMALAVGSKAADEDELKEIAFDSSLVFIPAEFRPAPLQNMLPSLMAPLRTLTGTTEVHVNKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTYQTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTREHVPQLLLLLMAGPSEDAYLQAANALVRSGVLTFCVGTNRADKAELEHIAFNPSLVYLMDDFRSLPSLPQQLIQPLTTYVSGGVQEVPLSQPESKRDILFLFDGSVNVLGQFPAVRDFLYRIIEELDVKPDGTRVAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSAGSRIEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILAAESLPKIGDLQSQIVSLLKAEQGSGPVSGEKDVVFLIDGSEGVRSGFPLLKDFVQRVVESLDVGPDRVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDFAVAIPTFRELGTIQQVISERVIQLNREELSSLKPILTPSTGAGVGSKKDVVFLIDGSRNAGPEFQYIRTLIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAHFSKDEVQNAVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKSDDEVDDSAVELKQFGVAPLTIARHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPITTLTSQQIHQILASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGVVQFSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLVFTVREFRELPNIEERVMLSFGPSGATPQPPGVDLPSPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFASEIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAI
Protein: DNA-directed RNA polymerase subunit Rpo3 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit D) (B8YB56)
Organism: Saccharolobus shibatae (strain ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12) (Sulfolobus shibatae)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00320, ECO:0000269|PubMed:22848102}.
Interaction partners:
Sequence:
MSINLLHKDDKRIDLVFEGYPLEFVNAIRRAAMLYVPVMSIDDVYFIENNSPLYDEILAHRLALIPFTSEEALDTYRWPEECIDCTENCEKCYTKIYIEAEALNEPKMLYSKDIKSEDPSIVPISGDIPIVLLGANQKISLEARLRLGYGKEHAKFIPVSLAIVRYYPKVEILGNCEKGATVCPEGVFELKDGKLSVKNELACTLCEECLRYCNGLIRISSVEDKYILELESVGSLKPERILLEAGKSIIRKIEELEKKLVEVIK
Protein: Component of DNA helicase/primase complex (Q77CB0)
Organism: Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)
Interaction partners:
Sequence:
MEREAFSAEVFLNFTSMHEIQPIVKRIRQLEAARLPAAARPPLGWFRAAAAAESPLDFAPRELPFAAYLITGNAGSGKSTCIQTLSETLDCVITGATRVAAQNVYLKLAAAYHSRHINTIFQEFGFRANHVQAQLGRHQYVCAASPPSIQDVQFRDLVYYWEVLGDISRRLLGAAASRGQFEALRAAELAAGRPRGAVERLAPCVHGSLPAFARSNVIVIDEAGLLGRHILTAVVYCWWLINAAHDSAQYRDGAMPVVVCVGSPTQTDSLESTFEHHKLKCRVRSSENVLTCLITNPTLREYAAIPHNWTIFINNKRCQEYEFGELLKTLEYGLPVTEEHLALVDKFVVPDAFINNPANLQGWTRLYSSHREVSAYMSRLHAHLKVAEGRSRFVVFTLPVYTFVNIRTFEDYRTATGQPGLGVEKWLQANSGRITNYSQSRDQDAQSPHCEVCSAKGLVVARSDVTYVLNSQVTVTTRLKKLVFGFSGTFADFIAVLRDDGFVRAQSETSVEYAYQFLAALLFGGMIAFYNFLRTPGLDPGRVDEAYRRLARATQEALGPAADDAVDWRGLAADRAAGSEAGAGDNDDDLVFAALDEGTLDLLYCNYEFQRPTSAHEIYAQFLLLKNLFAARFDVCRTLFGAAFADAPFEAYVDNLSFKGCEVFTGSLRGGLVSMALQTDTYTLMGYAHAPPSLLSEEPGRRRLPDGVAELLSTLDVPNIVVRDQRGFVSVLHTNVSEFVEALDDKELEMAVSVDYGISSKLAMTIARSQGLSLDKVAVCFARGNLRLNAVYVALSRSVSSRFLRMNLNPLREPHERDTMISEHILAALRDENVHIVY
Protein: Lipid-binding protein (Q59KV8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Lipid-binding protein
- Multifunctional tryptophan biosynthesis protein
- Tryptophan synthase
- Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
- Phosphoserine aminotransferase
Sequence:
MHRTYSLRSTRAPTASQLQAPPPPPSSTKSKFFGKGSISHTFRKQAAGALGPELSRKLAILIKMEKNLMRSIEITSRERKDVAKQLSLWGEANEDDISDITDKLGVLIYEVGELEDQFIDRYDQYRITLKSIRDIEGSVQPSRERKQKITDQIAYLKYKDPQSPKINVLEQELVRAEAESLVAEAQLSNITREKLKTAFNYQFDSIREHAEKIALIAGYGKALLELLDESPVTPGETRPAYDGYEASKQIIIDAENALASWTFDSAVVRPTLSLAAHDEEAEEDLEGAYEDDELANEAENLRIAEKDFDEVEAKIAA
Protein: Prickle homolog 1b (Prickle-like protein 1b isoform X1) (Q5SP54)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
Sequence:
MSLETTSGIWPITRAPDMDSRGAKAFGFQRSSTSDDDSGCALEEYTWVPPGLRAEQVQIYFSCLPEEKVPYVNSPGEKHRIRQLLYQLPPHDNEIRYCQSLSDEERRELHMFSMQRKKEALGRGTPKLLPRALQHNCEHCKENINGGEMAVFASRAGPGPCWHPACFTCYTCHELLVDLIYFYHNGNIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFSCFECETILGGQRYIMKDGRPFCCGCFESLYAEYCEACGENIGVDHAQMTYEGVHWHATDKCFCCAQCKTSLLGCPFLPKDGRIYCSKDCSLGEDVQASDSSDSAFQSARSRESRRSIRMGKSSRPTEQCQQTKLYSATDYRTSSLCGDNTETMCHQLERINFTEDNYWRERDEQEAPEDSVEDWAEHEDYMTQLLLKFGDRGVIHAEDSRAAEPWMVKDTETNRTKPEIKMSGHNLASKKHHTDMYWAQSQDGLGDSAYGSHPGPASARKIQELEMDQGTVPGFWSEPRQWYEDSLECITSELRKADHNIGDSMDSLALSNITGASVDGDSKDRQTIYSLQNMKDQEREIEECDNISNVGTLNSSMLHRSANSLRSLNSELGHEETLGQGAREDDEEDRIPPYFGAEPPSPLNLPVLRRTKSQSQPQSRSQQVKFSDDVLEKGYYGALGLRQPPMSERTRRRTFHIEEEAAAAAERRPANRHHHKRRHSRKTRSENALHLPSKNRGKLHVVPQVISSNMPEPRNGILLNHSAHSQHPYRQTTSDFPQQGMVRLDQFQDFCDDDEEDDWCSTCSSSSSESEEEGFFLGQPIPKPRSQSFHYYTEDYPTRVTALTPPFGSRTKLKKKGHKGKNCIIS
Protein: Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1) (O54887)
Organism: Mus musculus (Mouse)
Function: May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Concentrates in spermatid centrioles during flagellogenesis. Associates with acrosomal vesicle in sperm. In elongating spermatids, accumulates in a ring-shaped structure originating from the chromatoid body.
Interaction partners:
Sequence:
MASVVVKTIWQSKEIHEAGDPPAGVESRAQLVPEAPGGVTSPAKGITKKKKAVSFHGVEPRMSHEPMHWCLNLKRSSACTNVSLLNLAAVEPDSSGTDSTTEDSGPLALPGPPASPTTPWAPEDPDITELLSGVNSGLVRAKDSITSLKEKTTRVNQHVQTLQSECSVLSENLERRRQEAEELEGYCSQLKGPRPDVLTQENCRKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQELEQKLEAGLSRHGLSPATPIQGCSGPPGSPEEPPRQRGLSSSGWGMAVRTGEGPSLSEQELQKVSTGLEELRREVSSLAARWHQEEGAVQEALRLLGGLGGRLDGFLGQWERAQREQAQSARGLQELRGRADELCTMVERSAVSVASLRSELEALGPVKPILEELGRQLQNSRRGADHVLNLDRSAQGPCARCASQGQQLSTESLQQLLERALTPLVDEVKQKGLAPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEAVRAKNLLLTDKMKPEEKVATLDYMHLKMCSLHDQLSHLPLEGSTGAMGGGSNGGAPPKRGSPGSEQ
Protein: Integrin subunit alpha E (M0R6T8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Interaction partners:
- Integrin beta
- Cadherin-1
- Integrin beta-1
- Integrin beta
- Integrin beta-3
- CD69
- Forkhead box P3
- Basic leucine zipper transcriptional factor ATF-like 3
- Receptor-type tyrosine-protein phosphatase C
- C-C motif chemokine receptor 7
Sequence:
MKWFFHALLCVASLKPLGAFNVDVDWSWVTALQPGAPSVLNSLLHQDPSNNQTCLLVARRSSNRNSAVLYRCATSIIPDEIGCQPVEHILMPKGRYQGVTLVRNHNGVLVCIQVQSRKPRSLNSELTGACSLLTPNLDLQAQAYFSDLEGVLDLGASVNSGDYYGSKGGSTGEETKSARRLRRQAVEEEDEEEAGTEIAIVLDGSGSIEPSDFQKAKDFISTMMRNFYEKCFECNFALVQYGGVIQTEFDLLDSRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFRDPLNLTTVISSSKMQGVVRFAIGVGNAFENNNTYRELKLIASDPKAAHTFKVTNYSALDGLLSKLQQRIIHMEGTVGDTLQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALLYNTQNGRGRFLNQTAKEDFRAAQYSYLGYSVAALHKAHGVSYVAGAPRHKLRGAVFELQKEDGEETFMRRIEGEQMGSYFGSVLCPVDINMDGITDFLLVAAPFYHIRGEEGRVYVYRVHEQDAPFSLVYTLSGYPGLTSSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLHASPSQQIRASSVALGLYYFGMSVSGGLDFSGDDLADITVGSQDVAVVLRSRPVVDLTVSMTFTPDALPMAFKDKMDVELCFKVDSSAVPSEPGLRGMSLNFTVDVDVTKQKQRLQCADRSCCQSCLMKWSGGSSLCEHFGLISTEEELCEDDCFSNITIKVSYEFQTSEERRNHPNPILDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTAISQQDLVVGITKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPLSPDIQCDDPKPVASVLVMNCKIGHPILKRSSVNVSVTWQLEESIFPNRTADITVTISNSNEKSLARETHSLQFRHAFIAVLSRPSVMYMNTSQSSSDHKEFFFNVHGENHFGAVFQLQICVPITLRDLQIIRVKHLTKTQAHTECTQSQEPTCGSDPVQNVEEWHSVICAITSNKENVTVAAEISMGHTKQLLRDISELQILGEISFNKSLYEGLNAENHRTKITVIFLKEEKPHSLPLIIGSSIGGLLVLVVIIAILFKCGFFKRKYKQLNLESVRKAQLKSDSLLED
Protein: ATP synthase epsilon chain, chloroplastic (ATP synthase F1 sector epsilon subunit) (F-ATPase epsilon subunit) (P0C2Z3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00530}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00530}.
Interaction partners:
- ATP synthase subunit c, chloroplastic
- ATP synthase subunit alpha, chloroplastic
- ATP synthase subunit b, chloroplastic
- ATP synthase subunit alpha
- ATP synthase subunit beta, chloroplastic
- ATP synthase subunit a, chloroplastic
- F-ATPase gamma subunit
- ATP synthase subunit d
- Os06g0714700 protein
- Os02g0750100 protein
Sequence:
MKLNLYVLTPKRIIWDCEVKEIILSTNSGQIGVLPNHAPINTAVDMGPLRIRLLNDQWLTAVLWSGFARIVNNEIIILGNDAELGSDIDPEEAQQALEIAEANVSRAEGTKELVEAKVALRRARIRVEAVNWIPPSN
Protein: Large ribosomal subunit protein eL32 (60S ribosomal protein L32) (Ribosomal protein 49) (P04359)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Large ribosomal subunit protein P1
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein eS12
- Large ribosomal subunit protein eL18
- Small ribosomal subunit protein eS1
- Large ribosomal subunit protein uL1
- Large ribosomal subunit protein eL22
- Large ribosomal subunit protein uL16
- Ribosomal protein S30, isoform A
Sequence:
MTIRPAYRPKIVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHGVSSKKRKEIVERAKQLSVRLTNPNGRLRSQENE
Protein: Aminoglycoside 6-adenylyltransferase (EC 2.7.7.-) (6-O-adenyl-transferase) (AAD(6)) (ANT(6)) (Aminoglycoside inactivating enzyme) (Sm inactivating enzyme) (Streptomycin 6-adenylyltransferase) (P17585)
Organism: Bacillus subtilis (strain 168)
Function: Mediates bacterial resistance to streptomycin. Adenylates streptomycin on the O-6 residue. Adenylates streptidine on the O-6 residue. Does not act on spectinomycin, neomycin-B or kanamycin. Specific for ATP and GTP nucleotides incorporating a purine ring. No reaction with CTP or UTP.
Subcellular location: Cytoplasm {ECO:0000305|Ref.5}.
Interaction partners:
- Ribosome protection protein VmlR
- Putative HAD-hydrolase YfnB
- Streptothricin acetyltransferase A
- Tunicamycin resistance protein
- Probable guanidinium efflux system subunit GdnD
- Multidrug resistance protein 2
Sequence:
MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQWLEIFGKRIMMQKPEDMELFPPELGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGLVKVLLDKDSFINYKVTPNDRQYWIKRPTAREFDDCCNEFWMVSTYVVKGLARNEILFAIDHLNEIVRPNLLRMMAWHIASQKGYSFSMGKNYKFMKRYLSNKEWEELMSTYSVNGYQEMWKSLFTCYALFRKYSKAVSEGLAYKYPDYDEGITKYTEGIYCSVK