wanglab/gogpt-training-data huggingface dataset:
Protein: Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) (Q9C713)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:16251277, ECO:0000305|PubMed:16297076}.
Interaction partners:
- Methionine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Glutamate--tRNA ligase, cytoplasmic
- Isoleucine--tRNA ligase, cytoplasmic
- Glutamine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, chloroplastic/mitochondrial
- Proline--tRNA ligase, cytoplasmic
- Methionine--tRNA ligase, chloroplastic/mitochondrial
- glutamine--tRNA ligase
- Proline--tRNA ligase, chloroplastic/mitochondrial
Sequence:
MATIVASKEFTGNPRRQLAKLFDVSLKLTVPDEPNVEPLIEPGKFGDYQCNNAMGLWSLIKGKGTQFRGPPAVGQALIQSLPTSEMVESCSIAGPGFVNVVLSSKWMAKSIENMLVDGIDTWAPTLSVKRAVVDFSSPNIAKEMHVGHLRSTIIGDTLARMLEYSKVEVLRRNHVGDWGTQFGMLIEFLFEKFPDTESVTETAIGDLQVFYRESKLKFDLNPEFKEKAQQAVVRLQGGDPVYRQAWAKICEISRNEFAKVYKRLRIELEEKGESFYNPYIANVIEELSSKGLVEESKGARVIFIEGFKIPLIVVKSDGGFNYASTDLTALWYRLNEEKAEWIIYVTDVGQQQHFDMFFKAARKAGWLPDDDKTYPRVSHVGFGLVLGDDNKRFRTRAAEVVRLADLLDEAKDRSKAALIERGKDKEWSPEELDQIAEAVGYGALKYADLKTNRITGYTFSFDQMLNDKGDTAVYLLYAHARICSIIRKSGKDIDELKKTGKIALDHAAERALGLHLLQFAETVEEACTTLLPNVLCKYLYYLSEEFTKFYSNCQVNGSAEETSRLLLCEATAIVMRKCFHLLGITPVYKL
Protein: 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (Q9Y7B6)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Pantoate--beta-alanine ligase
- Branched-chain-amino-acid aminotransferase atnH
- Aminotransferase atnJ
- Branched-chain-amino-acid aminotransferase
- Branched-chain amino-acid transaminase, putative
- Branched-chain amino-acid transaminase, putative
- Branched-chain-amino-acid aminotransferase
- dihydroxy-acid dehydratase
- Hypothetical dihydroxyacid dehydratase
- dihydroxy-acid dehydratase
Sequence:
MTFLRIATKRAIYLHRPANPALPTSSILPVLHSTNVATRVPSPCAIRHSSHSPLGAAQANPRKKVTMQTLRNLYKKGEPITMLTAHDFPSAHVADAAGMDMILVGDSLAMVALGMQDTSEVTLDDMLVHCRSVARAAQSAFTVSDLPMGSYEVSPEQALQSAIRIVKEGRVQGVKLEGGEEMAPAIKRITTAGIPVVGHIGLTPQRQNALGGFRVQGKSTTDALKLLKDALAVQEAGAFMIVIEAVPPEIASIVTQKLSVPTIGIGAGNGCSGQVLVQIDMTGNFPPGRFLPKFVKQYANVWNEALQGIQQYREEVKSRAYPAEQHTYPIPKEELVEFQKAVDELPEEK
Protein: Y' element ATP-dependent helicase YML133C (EC 3.6.4.12) (Q03099)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
Interaction partners:
- Y' element ATP-dependent helicase YJL225C
- Y' element ATP-dependent helicase protein 1 copy 3
- Putative uncharacterized protein YHR219W
- Uncharacterized protein YCR108C
- UPF0479 membrane protein YEL077W-A
Sequence:
MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEIASARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRRYGYNLAPHMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLATAQRIRRRYNKNSSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKFFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHWVDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVGE
Protein: Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) (O60105)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Adenylosuccinate synthetase
- Bifunctional purine biosynthesis protein ade10
- Bifunctional purine biosynthetic protein ADE1
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Adenylate kinase
- Adenine phosphoribosyltransferase
- Phosphoribosylformylglycinamidine synthase
- Adenylate kinase isoenzyme 6 homolog
- Adenosine kinase
- AMP deaminase
Sequence:
MEDYGSYSTPLTARYASAEMSHLFSREMRINTWRQLWLNLAIAEKQLGLTQITDEAIEQLKAHVKITAPEFEIAAKEEKRQRHDVMAHIYTYGLAAPAASGIIHLGATSCFVTDNADLIFLRSAMDLLIPKLVNVINRLSQWSLRYKDIPTLGFTHYQPAQLTTVGKRATLWIQELLWDLRNFVRARNDIGFRGVKGTTGTQASFLALFEGDHAKVEELDKLVAKLSGFDNVYPVTGQTYDRKIDIDVLQPLASFGATAHKIATDIRLLANLKEVEEPFEAGQIGSSAMAYKRNPMRCERICSQARYIMNLIPNALNTASVQWFERTLDDSSNRRSLLPEAFLFTDSVLKILLNVISGMVIYPKVIQKHIRAELPFMATENIIMAMTKHGASRHECHEQIRVLSHQAGRVVKEEGGDNDLIERIKNTPYFAPIYDELDSLLDASTFVGRAPEQTESFVNKDVSQALAPFKSMITEEKVDLAV
Protein: RE59988p (Q8MYX3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00201}.
Interaction partners:
Sequence:
MLSMQELMDMRMQQQLAHEIYRQQIMQRIPDPFPSMLPFNMPHQQPHMMLPSRPTLPGVEAKLDNNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASMHKYQPRLHIIRSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQDSTGSVSPAYYGATHPVANPMSPYLRHHLSYGPSGAAGLPPSIAAAYFGGVPPQILPMPPATYAPTVAPVSPVASQPVGSSTPTTSPRPSTSTKRNSFSISAILAY
Protein: GM06782p (Q95S75)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGIQCFGGELPFFFLSGWILKKIGHVNAMSVVLFGFGVRFILYSMLQNPWYILPIELMNGVTFGLFYATMASYASIVAPPGTDATMQSLVGAIFEGVGVSMGSLIAGQLFETVTARTTFEIFGIGAFIVFVIHVCIQLYLQRNSNIDENGKGTVASASATASPSAPLETDIPKNTDHKDGDGFREVDLS
Protein: Plastidic glucose transporter 4 (AtpGlcT) (Q56ZZ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the efflux of glucose towards the cytosol.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000305|PubMed:10810150}; Multi-pass membrane protein {ECO:0000305|PubMed:10810150}.
Interaction partners:
- Maltose excess protein 1, chloroplastic
- Uncharacterized protein T21H19_30
- Triose phosphate/phosphate translocator TPT, chloroplastic
- 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic
- ADP,ATP carrier protein 2, chloroplastic
- At2g39500/F12L6.16
- Glucose-6-phosphate/phosphate translocator 1, chloroplastic
Sequence:
MQSSTYAVKGNAAFAFQRRTFSSDRSTTSTGIRFAGYKSLATTGPLYCSGSEAMGATLARADNGIQSVMSFSSVKARSVRAQASSDGDEEEAIPLRSEGKSSGTVLPFVGVACLGAILFGYHLGVVNGALEYLAKDLGIAENTVLQGWIVSSLLAGATVGSFTGGALADKFGRTRTFQLDAIPLAIGAFLCATAQSVQTMIVGRLLAGIGIGISSAIVPLYISEISPTEIRGALGSVNQLFICIGILAALIAGLPLAANPLWWRTMFGVAVIPSVLLAIGMAFSPESPRWLVQQGKVSEAEKAIKTLYGKERVVELVRDLSASGQGSSEPEAGWFDLFSSRYWKVVSVGAALFLFQQLAGINAVVYYSTSVFRSAGIQSDVAASALVGASNVFGTAVASSLMDKMGRKSLLLTSFGGMALSMLLLSLSFTWKALAAYSGTLAVVGTVLYVLSFSLGAGPVPALLLPEIFASRIRAKAVALSLGMHWISNFVIGLYFLSVVTKFGISSVYLGFAGVCVLAVLYIAGNVVETKGRSLEEIELALTSGA
Protein: Genetic interactor of prohibitin 5, mitochondrial (Required for respiratory growth protein 5) (Q12393)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}.
Interaction partners:
- Required for respiratory growth protein 8
- Protein PET130
- Required for respiratory growth protein 1
- Required for respiratory growth protein 7
- Required for respiratory growth protein 9
- Increased recombination centers protein 19
Sequence:
MASQVNALLLPVIESTPLHQITKVALTTTLTSKQSDYKFKEIAVPLTKSLQLYEKAQRRQDLRASLKALESIIYQTHFQWNNPLPRHAHLFQKHYHFLLTHWPFENHRDLVDSIAVNNGKLNSTSSRSVWLKADWITLFNVKNPWVQTPPSLMRLSGTDLDTFTPERIFLINSLGNHYKFLIANSHLSYNHKKYPSPGVQIPVRNALGEVSPAKQIAQLFARQLSHIYKSLFIENPPLSPENELALTAVFYDETVERRLRRLYMRACARAYTTTNADSTTEPLMFHCTRWEVD
Protein: Aryl hydrocarbon receptor nuclear translocator (Q98SN3)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAATAANPEMASDVSSLGAAVGSGNPGAGAQTGGGIVQRAAKRRPGLDFDDDGEGNSKFLRCDDDPMPNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGTYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVGKLREQLSTSENALTEGTKPWCLSNKDPAAPPESASKGRILDLKTGTVKKEGQQSMRMCMGSRRSFICRMRCGNSSVDAVSVNRLSFMRNRCRNGLGATKDGEPHYVVVHCTGYIKAWPPAGVSLPDDDPDAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTEFISRHNTEGIFTFIDHRCVATVGYQPQELLGKDIVDFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQDSRPALSNPMQRPQLGQSVSLPLEMGTAQLPSRQQQQPQQTELEVVPGRESLAGYDHAQVPVQPVSAAGPEHSKPLEKAESLFNQERDPRFGEIYGSINADQNKAIPASSVPANPTLFPQGNAFTPSRPAENFRSSSMVPPVNIIQQQPAAAGRILAQISRHASPAQVSGSSWAAGTRPAFAAQVASQAVKTRPPSFSMGTFQGTPASFSPMAAPGSTASPSSAAYPNLSGRSAGFTTDAAQTPTPFQPRAAAEGVGMWPQWQGQHHSTAAGEQHVQQPSQPEAFPDMLTMLGDQGPNYNNEEFPELNIFPSFSE
Protein: WW domain-containing protein (Q55DG0)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- C2 domain-containing protein
- EGF-like domain-containing protein
- EGF-like domain-containing protein
- EGF-like domain-containing protein
- von Willebrand factor A domain-containing protein DDB_G0292188
- C2 domain-containing protein DDB_G0290753
- Transmembrane protein
- von Willebrand factor A domain-containing protein DDB_G0292028
- Winged helix repair factor 1
- GRAM domain-containing protein
Sequence:
MHYSIKIHNIKAYDLSLKKENHNANNINIDPYVKLKFDQFKKFKTESISKSITPTWKFEQTFHIPIMKDQDLKNKKVEIDCYDSCVIGGDNLIGGCSIDFFTVLNGPVHHKLVLRNKGVANGTIEFDLEMSEFLETKLTFRNLKTSYYAGALPITSTDQSIEKYLFYYILNSSKLQKVTKTLKTKKSNNLIWEDIDQIIYTIGLKELMICPIIFNILQYKNYNGETDPSLGQVTITLSSIVFDPKQITGPSYGGVDQKMVSFVEPIIHQNQVVGIMEGEIYFENVSQFIQLQDCVHTETGIQSFNGTNYPIKQQSQPQPVYNNTTNINTISQSPPKSFIQQSPPQQQPFIPQQSQSQPQPFVSQSPQQPFEPQQSQPFVPQQSQPFVPQQSQSQPQPIEPQPPQPFAPQQQQQQQQQQQQQQQQQQQQQQQQQQQKYQGPEWTDPRLPSGWVIRQDQSGKQYYVDHNTKSAHWTLPPHIAVLLNQPSTSNATTPLQPMKPIQQQGYVYPQQQQQQQQAVAGYPGAVQYGSYPQPQQGYVYPQYYQQYPTSTYMMSYPSSSCHSRHHHC
Protein: Twist-related protein 2 (Dermis-expressed protein 1) (Dermo-1) (Q9D030)
Organism: Mus musculus (Mouse)
Function: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:11809751}. Cytoplasm {ECO:0000269|PubMed:11809751}. Note=Mainly nuclear during embryonic development. Cytoplasmic in adult tissues.
Interaction partners:
- Twist-related protein 1
- CD44 antigen
- Runt-related transcription factor 2
- Zinc finger protein SNAI1
- Zinc finger protein SNAI2
- Zinc finger E-box-binding homeobox 2
- Zinc finger E-box-binding homeobox 1
- Transcription factor E2-alpha
Sequence:
MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAYSVWRMEGAWSMSASH
Protein: Solute carrier family 41 member 1 (Q8BJA2)
Organism: Mus musculus (Mouse)
Function: Na(+)/Mg(2+) ion exchanger that acts as a predominant Mg(2+) efflux system at the plasma membrane. Transporter activity is driven by the inwardly directed electrochemical gradient for Na(+) ions, thus directly depends on the extracellular Na(+) ion concentration set by Na(+)/K(+) pump. Generates circadian cellular Mg(2+) fluxes that feed back to regulate clock-controlled gene expression and metabolism and facilitate higher energetic demands during the day (By similarity). Has a role in regulating the activity of ATP-dependent enzymes, including those operating in Krebs cycle and the electron transport chain.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8IVJ1}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8IVJ1}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Metal transporter CNNM2
- Transient receptor potential cation channel subfamily M member 6
- Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
- Transient receptor potential cation channel subfamily M member 7
- Metal transporter CNNM4
Sequence:
MSSKPEPKDIHQPNGTGPTPSPCSSDGPGREPLAGTSEFLGPDGVEVVVIESRANAKGIREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELKHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEPTPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD
Protein: Ankyrin repeat protein OPG025 (P17372)
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Function: Plays a role in the inhibition of host immune repsonse by counteracting the action of interferons on early events in the viral replication cycle.
Interaction partners:
Sequence:
MVNDKILYDSCKTFNIDASSAQSLIESGANPLYEYDGETPLKAYVTKKNNNIKNDVVILLLSSVDYKNINDFDIFEYLCSDNIDIDLLKLLISKGIEINSIKNGINIVEKYATTSNPNVDVFKLLLDKGIPTCSNIQYGYKIKIEQIRRAGEYYNWDDELDDYDYDYTTDYDDRMGKTVLYYYIITRSQDGYATSLDVINYLISHKKEMRYYTYREHTTLYYYLDKCDIKREIFDALFDSNYSGHELMNILSNYLRKQFRKKNHKIDNYIVDQLLFDRDTFYILELCNSLRNNILISTILKRYTDSIQDLLLEYVSYHTVYINVIKCMIDEGATLYRFKHINKYFQKFGNRDPKVVEYILKNGNLVVDNDNDDNLINIMPLFPTFSMRELDVLSILKLCKPYIDDINKIDKHGCSILYHCIKSHSVSLVEWLIDNGADINIITKYGFTCITICVILADKYIPEIAELYIKILEIILSKLPTIECIKKTVDYLDDHRYLFIGGNNKSLLKICIKYFILVDYKYTCSMYPSYIEFITDCEKEIADMRQIKINGTDMLTVMYMLNKPTKKRYVNNPIFTDWANKQYKFYNQIIYNANKLIEQSKKIDDMIEEVSIDDNRLSTLPLEIRHLIFSYAFL
Protein: Transcriptional activator HAP4 (P14064)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts a component of the CCAT-binding factor, which is a transcriptional activator and binds to the upstream activation site (UAS2) of the CYC1 gene and other genes involved in mitochondrial electron transport and activates their expression. Recognizes the sequence 5'-CCAAT-3'. HAP4 encodes a regulatory subunit of the DNA-bound complex and seems to provide the principal transcriptional activation domains. Does not bind DNA directly, but augments the binding of HAP2 and HAP3.
Subcellular location: Nucleus.
Interaction partners:
- Transcriptional activator HAP5
- Transcriptional activator HAP2
- Transcriptional activator HAP3
- Regulatory protein CAT8
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- General control transcription factor GCN4
- Regulatory protein ADR1
- DNA-binding protein RAP1
Sequence:
MTAKTFLLQASASRPRSNHFKNEHNNIPLAPVPIAPNTNHHNNSSLEFENDGSKKKKKSSLVVRTSKHWVLPPRPRPGRRSSSHNTLPANNTNNILNVGPNSRNSSNNNNNNNIISNRKQASKEKRKIPRHIQTIDEKLINDSNYLAFLKFDDLENEKFHSSASSISSPSYSSPSFSSYRNRKKSEFMDDESCTDVETIAAHNSLLTKNHHIDSSSNVHAPPTKKSKLNDFDLLSLSSTSSSATPVPQLTKDLNMNLNFHKIPHKASFPDSPADFSPADSVSLIRNHSLPTNLQVKDKIEDLNEIKFFNDFEKLEFFNKYAKVNTNNDVNENNDLWNSYLQSMDDTTGKNSGNYQQVDNDDNMSLLNLPILEETVSSGQDDKVEPDEEDIWNYLPSSSSQQEDSSRALKKNTNSEKANIQAKNDETYLFLQDQDESADSHHHDELGSEITLADNKFSYLPPTLEELMEEQDCNNGRSFKNFMFSNDTGIDGSAGTDDDYTKVLKSKKISTSKSNANLYDLNDNNNDATATNELDQSSFIDDLDEDVDFLKVQVF
Protein: Lmo1p (A0A1D8PR98)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Dck1p
- Dck2p
- Rho family GTPase
- Cell division control protein 42 homolog
Sequence:
MSESSRSINHKLNELLSKNNINKAKLDEATALSYATILKTNILGKDKQEKVNSIVVLAKLLDCIIGSDAISDEFVHILDHTLFQTLFSIVSANMSSETYKAILKISVIDISGTIFRDKDDSIEKYLPLYESLIEYLDVIDIITSKLFLQDNKITFNSIKLVTDLITKSLKFEYSGIITLAGRLKHVTFFSTVGNLLETDDKATIEAIENLKVAYHKLNQYLGATAFDMSIKSHQTMLNNLFIFLETSLNEYGTPATTEEYVKAGFTDNPRQFVVENFSILLAMNLKVFLKDPNFTFKKRFHEELMMSDHARTFPLYQFISKCTDLWTDIFEKKNDFPKINSAILSWDLMIYYTMNHGLVLWQETRAQLDNKVDIAKIFQLLYSNIEEIEKSGQSIDEALASEGGAIGDVRHFQINKIEQSLKEKWAGKLFEFYKELDREVHEFVREQRILKLMEGNMITLNSNTGSNQILLRLTPNRQYLESEDNSIKVPVVEIVDIKIVNVGGATGVDKKSLVSIKTNLYRITLVGKENKHLLSFFSDSQSAFDGLTMMLGKGSVSEETTKQIDTLIEIRSKTQLLDLNEIDDSDDEEDEADEDADEVLEDLLEVINEDFYYK
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (A0A8I6A351)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MIQERLIASLEKEKDRVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTAAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSANNKCCINGASTVVTTIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEGRWFHFNDSTVTVTDEETVGKAKAYILFYVERQARAGADKL
Protein: Protein TRIGALACTOSYLDIACYLGLYCEROL 1, chloroplastic (ABC transporter I family member 14) (ABC transporter ABCI.14) (AtABCI14) (Q8L4R0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required during embryogenesis. Permease involved in lipid transfer from the endoplasmic reticulum (ER) to plastids, and necessary for thylakoids formation.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000269|PubMed:12743031, ECO:0000269|PubMed:16199613}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein TRIGALACTOSYLDIACYLGLYCEROL 2, chloroplastic
- Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic
- ABC transporter I family member 17
- ABC transporter I family member 6, chloroplastic
- Protein ABCI7, chloroplastic
- Triacylglycerol lipase SDP1
- AT5g24690/MXC17_8)
- Protein TRIGALACTOSYLDIACYLGLYCEROL 5
- Protein TRIGALACTOSYLDIACYLGLYCEROL 4, chloroplastic
- ABC transporter I family member 19
Sequence:
MMQTCCIHQSFCFPHRVFPRFDASIGIKPPKLCQVGFIGKTQSYGISSPIRQRRLYVNLNANDGHPSMSMLEEETSTENNAPSQEAELPFSKWSPSKYIWRGLSVPIIAGQVVLRILKGKIHWRNTLQQLERTGPKSLGVCLLTSTFVGMAFTIQFVREFTRLGLNRSIGGVLALAFSRELSPVITSIVVAGRMGSAFAAELGTMQVSEQTDTLRVLGADPIDYLITPRVIASCLALPFLTLMCFTVGMASSALLSDAVYGISINIIMDSAHRALRPWDIVSAMIKSQVFGAIISVISCSWGVTTTGGAKGVGESTTSAVVMSLVGIFIADFVLSSFFFQGAGDSLKNCV
Protein: WH2 domain-containing protein (Q55BN3)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Wiscott-Aldrich syndrome protein
- WASP-related protein
Sequence:
MPPPPPPPPAPVAPAPPKTAERGALLNSIQKGAKLKKTVTVDKSKPVLQADKSGGGGGGGMPRPGMGGPPMGMFTPSPGGLKKAGGPPPLIAKQSPAPAPPTSSPLKKPPPPLIAKNTASPPPPVASKPAPPSFKAPPPVASKPAPPSFKAPPPVASKPAPPSFKAPPPVASKPAPPSFKAPPPVGARQAPAPPMKR
Protein: Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD (EC 3.5.1.n3) (P76472)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (Probable).
Interaction partners:
- Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
- Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
- Bifunctional polymyxin resistance protein ArnA
- Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
- Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF
- UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase aminotransferase)
- Lipopolysaccharide core heptose
- UDP-glucose 6-dehydrogenase
Sequence:
MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIEAKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
Protein: Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) (Q6IA69)
Organism: Homo sapiens (Human)
Function: Catalyzes the final step of the nicotinamide adenine dinucleotide (NAD) de novo synthesis pathway, the ATP-dependent amidation of deamido-NAD using L-glutamine as a nitrogen source.
Interaction partners:
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
- NAD-capped RNA hydrolase NUDT12
- NAD kinase 2, mitochondrial
- NAD-dependent protein deacetylase sirtuin-1
- NAD-dependent protein deacetylase sirtuin-3, mitochondrial
- Nicotinate-nucleotide pyrophosphorylase [carboxylating]
- NAD-dependent protein deacylase sirtuin-5, mitochondrial
- NAD-dependent protein deacetylase sirtuin-7
- NAD-dependent protein lipoamidase sirtuin-4, mitochondrial
Sequence:
MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALVESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWTPHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGNEEVLADVRTIVNQISYTPQDPRDLCGRILTTCYMASKNSSQETCTRARELAQQIGSHHISLNIDPAVKAVMGIFSLVTGKSPLFAAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGVHGGLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQFCIQRFQLPALQSILLAPATAELEPLADGQVSQTDEEDMGMTYAELSVYGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFFSKYSMNRHKMTTLTPAYHAENYSPEDNRFDLRPFLYNTSWPWQFRCIENQVLQLERAEPQSLDGVD
Protein: Chemokine CK-1 (Q9PT06)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MISCRVCVLAALFSLLIITLIPTTQSADCCLKFTRRPVHCRWLKGYTFQDITSSCDLNAVIFQNLRNKFVCADPSQDWTKRVQRCLRKRQEKESQLKKRV
Protein: Spermatogenesis-associated protein 46 (Q5T0L3)
Organism: Homo sapiens (Human)
Function: Plays a role in spermiogenesis and fertilization.
Subcellular location: Nucleus membrane {ECO:0000250|UniProtKB:Q4FZF2}. Note=Located throughout the subacrosomal area. {ECO:0000250|UniProtKB:Q4FZF2}.
Interaction partners:
- Casein kinase I isoform alpha
- Protein Mdm4
- GTPase-activating protein and VPS9 domain-containing protein 1
Sequence:
MENFSLLSISGPPISSSALSAFPDIMFSRATSLPDIAKTAVPTEASSPAQALPPQYQSIIVRQGIQNTALSPDCSLGDTQHGEKLRRNCTIYRPWFSPYSYFVCADKESQLEAYDFPEVQQDEGKWDNCLSEDMAENICSSSSSPENTCPREATKKSRHGLDSITSQDILMASRWHPAQQNGYKCVACCRMYPTLDFLKSHIKRGFREGFSCKVYYRKLKALWSKEQKARLGDRLSSGSCQAFNSPAEHLRQIGGEAYLCL
Protein: VPS39 subunit of HOPS complex (A0A8I6AL66)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MHDAFEPVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIRKDVGCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSFLLATVPWSHRILIGSAVSPQHTETGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDAKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVLNEEGICTQKCALNWTDIPVAMEHQPPYIVAVLPRYVEIRTLEPRLLVQSIELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAVSLHFLYQFIEICIETTKLGTLEDPTHVMGLYPDLLPTDYRKQLQYPNPLPTLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKQKLLQIIDTTLLKCYLHVSCRHASPALKVSGPSRGLCWTPTRETLQRDPT
Protein: DNA repair and recombination protein RAD52 (A0A1D8PM97)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- DNA repair protein RAD51 homolog
- DNA-dependent ATPase
- DNA repair and recombination protein RAD52
- DNA-dependent ATPase
- Replication protein A subunit
- Crossover junction endonuclease MUS81
- Rfa2p
- DNA 3'-5' helicase
- SUMO-conjugating enzyme UBC9
- DNA ligase 4
Sequence:
MTTSYLDTENDNDIDDNEEEEEEELANLPSTVKFFPNLSDLLDDEEYQDDDDDDGTNNNNTVINEWALRKFGTLQMKLEKMQHSRDTFQSFGSRDNLTNFSRNILYNLANEVFGFDGWSTTILDCNLTKRENKDENKYSALCVVKIRLILKDGTFREQSGQAESTNMPYKHMCYASARKKAVTDAIKNAIVGLRDLYLEYEQEQLMKQFAPEYDI