wanglab/gogpt-training-data huggingface dataset:
Protein: Methylsterol monooxygenase 1-1 (EC 1.14.18.10) (EC 1.14.18.9) (Sterol 4-alpha-methyl-oxidase 1-1) (AtSMO1-1) (Q8L7W5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Non-heme iron oxygenase involved in sterols biosynthesis by catalyzing the removal of the first methyl group at the C-4 position. 4,4-dimethyl-9-beta,19-cyclopropylsterols such as 24-methylenecycloartanol are the preferred substrates. Acts as a rate-limiting enzyme in the sterol pathway via interaction with ACBP1; sterols serve as lipid modulators for gene expression of homeodomain-leucine zipper IV transcription factors. Together with SMO1-2, involved in the maintenance of sterol composition to balance auxin and cytokinin activities during embryogenesis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:28500265, ECO:0000269|PubMed:31341004}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Ergosterol biosynthetic protein 28
- Sterol 14-demethylase
- Cycloartenol-C-24-methyltransferase
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
- Delta
- 7-dehydrocholesterol reductase
- Putative Delta
- Putative sterol 14-demethylase-like protein
Sequence:
MIPYATVEEASIALGRNLTRLETLWFDYSATKSDYYLYCHNILFLFLVFSLVPLPLVFVELARSASGLFNRYKIQPKVNYSLSDMFKCYKDVMTMFILVVGPLQLVSYPSIQMIEIRSGLPLPTITEMLSQLVVYFLIEDYTNYWVHRFFHSKWGYDKIHRVHHEYTAPIGYAAPYAHWAEVLLLGIPTFMGPAIAPGHMITFWLWIALRQMEAIETHSGYDFPWSPTKYIPFYGGAEYHDYHHYVGGQSQSNFASVFTYCDYIYGTDKGYRFQKKLLEQIKESSKKSNKHNGGIKSD
Protein: Small ribosomal subunit protein mS33 (28S ribosomal protein S33, mitochondrial) (MRP-S33) (S33mt) (Ganglioside-induced differentiation-associated-protein 3) (Q9D2R8)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9Y291}.
Interaction partners:
- Small ribosomal subunit protein mS31
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein bS21m
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein mS40
- Small ribosomal subunit protein uS3m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein mS23
- Small ribosomal subunit protein mS38
Sequence:
MSPLSEYALRMSRLSARIFGEVARSTDSKSMKVVSLFSEQPLAKKKETYDWYPNHNTYFALMGNLRFLGLYRDEHQDFKDEQRRLKKLRGKGKPRKGEGKRATKKK
Protein: DNA helicase (EC 3.6.4.12) (Q8I5T4)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- DNA replication licensing factor MCM3
- DNA helicase
- DNA helicase
- Origin recognition complex subunit 5
- ATPase AAA-type core domain-containing protein
- Origin recognition complex subunit 2
- MCL1 domain-containing protein, putative
- DNA replication licensing factor MCM2
- Origin recognition complex subunit 1
- DNA polymerase II subunit 2
Sequence:
MIGIQEGRAFFNPTRNPNNRPENNIRIEENLPSLNEVYNYFQDFLSRYSSNTLKEGNLKRTLFENVKNNNFTLDLKLDDIYKQQTVFENNEISATPRSERKMKKPENYSAILARALSERPLTYLPTIERVCYEVCETANILNDEDEHLNYIQINLLNTFIRPTPIRGLLAATQERFVVVPGIIVQASKPQHKMRKITLQCRYCDHKMSIDVPLWRDKPQLPPYCRYSSTMKSSMGLGNAMDSQLGCNGVLEPYVILPNECTFVDIQSLKMQELPEAVPTGDMPRHLQLNVTRYLCEKMIPGDRVYVHGVLTSYNPNPRPTRADGTNFSYLHVLGFQKYDDMSGNDLNFDVEERNELTLLAAEHNIHEKIFKSIAPELYGMDEVKKACACLLFGGTRKRIGEETKIRGDINMLMLGDPSVAKSQILKFVNRCAPVSVYTSGKGSSAAGLTAAVMRDSQGVFSLEGGAMVLADGGVVCIDEFDKMRDDDVVAIHEAMEQQTISISKAGITTMLNTRCSVIAAANPSFGSYDDSQDTTYQHDFKTTILSRFDIIFLLRNKQDVEKDTLLCNHIVALHASKHKSQEGEIPLSKLTRYIQYAKREIAPLLSKEARDSLRNFYVQTRAEYRGDRRSVTKKIPITLRQLESLIRLAESFAKMELSQFATDKHVQMSIDLFSASTAETAKQCLIFETMSPLEQKAVKQAEDAILGRLGKGQRASRVNLFRELQLRGFDRSALSKALAILIKKGELQERGDRSVRRT
Protein: Anion exchange protein (D1FTM8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU362035}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362035}.
Interaction partners:
- Aryl hydrocarbon receptor nuclear translocator-like 1a
- Nuclear receptor subfamily 1 group D member 1
- BHLH-PAS transcription factor
- Period circadian protein homolog 2
- Cryptochrome 3
- GCMb)
- Period circadian clock 3.
Sequence:
MEMNESAKSPNQQSYWQEMGRWAGYEETYDVEAGRWSPSHISYLTFKSLVQIRRTMNTGVMMLDREEKTLSSIIEKIVDTLVSKKEIQPGDRDKVLQALMHKQSQSVETQPLTSNVEMEKFSVTEKRETADKTEASMVLVGALEFLERPTVVFVRLRDAVVLESALEAPVPVRFIFILIGPTIDGMNYHECGRAMAALLADKVFNQAAFQAQSDRELTDAVGDFMDCCIVIPPTEIQNESLLTSLIPFQKKLLQERLRPSNPKLRLDVKPRKPSKSSGPPPEDPLTRTGVPFGGMIRDMKRRYKHYISDLTDALNAQVLAAIIFIYFAALSPAITFGGLLALTFLIADKVDNMMGVSELMISTSLLGIIFCLIAAQPVLVIGFSGPLLVFEEAFFNFCKSQGIEYIVGRVWVGIWLVVIVVGIVALEGSFLVRFISRFTQEIFSILISLIFIYETFAKLLKIFREHPLTLNYEHLNTSVEDPWHSIVSYQKIFDNATGNVSVVRTVEHQAYPNTALLSMCLMFGCFSIAYYLRMFKNGKFLPGKIRRLLGDFGVPIAIFLMAAIDINIEDTYTQKLVVPKGLQVSNPSMRGWLINPFGEHKSFPVWMMFASIVPAILVFILIFLESQITTLIVSKPERKMVKGSGFHMDLLILVSMGGLSAFFGIPWLSAATVRSVSHANALTVMSKGPKPEIEKVLEQRVSGVVVALLVGLSILMEPILKMIPITALFGIFLYMGITSLSGIQLWDRMLLLLIPKKYHPNEPYATRVSTSKMHVFTAIQMVCLAVLWIVKSSPASLALPFVLILTIPLRMFMTGRLFTEQDMKFLDGDDSKATFEEEPGVDVYSETQMPL
Protein: G-protein comlpex beta subunit CpcB (Q4WQK8)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- 40S ribosomal protein S6
- 40S ribosomal protein S15, putative
- Elongation factor 2
- 40S ribosomal protein Rps16, putative
- 40S ribosomal protein S24
- 40S ribosomal protein S7
- 60S ribosomal protein L38, putative
- 40S ribosomal protein S9
- 60S acidic ribosomal protein P0
- Small ribosomal subunit protein uS2
Sequence:
MAEQMVLRGTLEGHNGWVTSLATSLENPNMLLSGSRDKTLIIWNLTRDEQAYGYPKRSLEGHSHIVSDCVISSDGAYALSASWDKSLRLWELATGETTRTFVGHTSDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKFTITDKGHTDWVSCVRFSPNPQNPVIVSAGWDKLVKVWELASCRLQTDHIGHTGYINTVTISPDGSLCASGGKDGTTMLWDLNESKHLYSLHAGDEIHALVFSPNRYWLCAATASSITIFDLEKKSKVDELKPEFIEKSSKAREPECISLAWSADGQTLFAGYTDNKIRAWGVMSRA
Protein: Matrin-3 (Nuclear scaffold protein p130/MAT3) (P43244)
Organism: Rattus norvegicus (Rat)
Function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs. May bind to specific miRNA hairpins.
Subcellular location: Nucleus matrix.
Interaction partners:
- RCG31562, isoform CRA_c.
- Heterogeneous nuclear ribonucleoprotein A1
- Non-POU domain-containing octamer-binding protein
- Heterogeneous nuclear ribonucleoprotein K
- RNA-binding protein 14
- RNA-binding protein FUS
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Splicing factor proline and glutamine-rich.
- Paraspeckle component 1
- Transitional endoplasmic reticulum ATPase
Sequence:
MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDTDQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDEKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGAQKTENPAEGKEQEEKSGEDGEKDTKDDQTEQEPSMLLESEDELLVDEEEAAALIESGSSVGDETDLANLGDVSSDGKKEPSDKAVKKDASATSKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDASDNSDGQNDENKEDYTIPDEYRIGPYQPNVPGGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKES
Protein: mRNA capping enzyme LEF-4 (EC 2.7.7.50) (EC 3.6.1.74) (Late expression factor 4) (LEF-4) (P41477)
Organism: Autographa californica nuclear polyhedrosis virus (AcMNPV)
Function: Component of the viral DNA-dependent RNA polymerase that catalyzes two reactions involved in viral RNA cap formation: an RNA 5'-triphosphatase that hydrolyzes the gamma phosphate of triphosphate-terminated RNA and a guanylyltransferase that reacts with GTP to form a covalent protein-guanylate adduct. Therefore plays an essential role in late and very late gene expression.
Subcellular location: Host cytoplasm {ECO:0000269|PubMed:9499802}. Host nucleus {ECO:0000269|PubMed:9499802}. Note=Preferentially in the host nucleus and associated with the virogenic stroma. {ECO:0000269|PubMed:9499802}.
Interaction partners:
Sequence:
MDYGDFVIEKEISYSINFSQDLLYKILNSYIVPNYSLAQQYFDLYDENGFRTRIPIQSACNNIISSVKKTNSKHKKFVYWPKDTNALVPLVWRESKEIKLPYKTLSHNLSKIIKVYVYQHDKIEIKFEHVYFSKSDIDLFDSTMANKISKLLTLLENGDASETLQNSQVGSDEILARIRLEYEFDDDAPDDAQLNVMCNIIADMEALTDAQNISPFVPLTTLIDKMAPRKFEREQKIVYGDDAFDNASVKKWALKLDGMRGRGLFMRNFCIIQTDDMQFYKTKMANLFALNNIVAFQCEVMDKQKIYITDLLQVFKYKYNNRTQYECGVNASYAIDPVTAIECINYMNNNVQSVTLTDTCPAIELRFQQFFDPPLQQSNYMTVSVDGYVVLDTELRYVKYKWMPTTELEYDAVNKSFNTLNGPLNGLMILTDLPELLHENIYECVITDTTINVLKHRRDRIVPN
Protein: chitinase-like effector (A0A0W0FPC8)
Organism: Moniliophthora roreri (Frosty pod rot fungus) (Monilia roreri)
Subcellular location: Secreted {ECO:0000305|PubMed:30220500}.
Interaction partners:
Sequence:
MLTLLPSLILLLSTLSLSTPANAGAAIAKAYYPGWGSDDFPLSKVTWSKYTHLTYAFAKTTKDGGLTLEGSNPGGLKPFVKAAHENGVKACFSIGGWTGSQYFSTAVSTPEKRTAFVKTIVDFAKKYDADCIDLNWEYPAKQGIGCNTIDKDDTPHFLSFLEELHAATELPISAAVGIVPFNDAAGNPITDVSGFAKVFEHIVIMNYDVWGPWGSTVGPNAPLNDTCAAPANQQGSAVSAVNAWIKAGMPAEKIVLGVPAYGHGFTVKKEDAFQKGSTTKLAKYPPFDNKNRPNGDKWDDKAGKDVCGNDNPAGGIFTFWGMVDNGYLKEDGTPKVPHRFDDCSKTPYVYNPDKQIMISYDDAKSMDHKGHFIKNFGLAGFSLWNAAGDYHDILVDAVRHGAGFKN
Protein: RRM domain-containing protein (Q9NLD1)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Ubiquitin-like domain-containing protein
- Heterogeneous nuclear ribonucleoprotein K homolog
- RRM domain-containing protein
- RNA-binding protein FUS
- Probable splicing factor, arginine/serine-rich 2
- Heterogeneous nuclear ribonucleoprotein A1
- RRM domain-containing protein
- BTB domain-containing protein
Sequence:
MSEEIKQEVKEEAPETTTEAKTEEAAPVAEVVAEVVTNGDKPAENGKTEEPSKYAETENYKKLIGLKMKPALADVVCEIYESGLLGPEDLDDRAVDIINSVNLDQAKFIFTEIKNSELFGVATKSLYVTSLIRSFKDRCRQQGAAAVTSGKLINGPELAALKNLLETTGYTIEVTIGQRKFGGPPPDWEGPATGPAGQGHEIYVGHIPTDVFEDTLVPLFEKSGKIWDLRLMMDPMSGASRGYAFVTYCNKEDAAAAAKTYDGHEISTGKPLKVNVSIANTRLFIGNIPKTKSKDEILEELKTHAEGVVDVIVYSVPDNEKIKNRGFCFVDFIDHKTASDIKRKIAQHKIRPFNADVYVDWAEHQEEPDEDTMSKVKVLYIRNIKEAVTEEKLNELFKEYASLDRVKKVKDYAFIHFNERDDCLKAMEEWNGKELEGTVVEASLAKPPQEKKKKPVMRGRGFGGAGGGAGNHGQRGGQRGGGQWGGNAGPGGYYPNHFNNGYDMPMPWGGGYGGDMGYGAYGGGYGGGYGGPGAYGDFGAYGGGGFRGGMRGSPRGGMGGGGGFRGGPPGRGGMANRRGRGKRPGDGRGGPASKRDNGKPDFSADVNMSTF
Protein: Serum amyloid A like 1 (Serum amyloid A-like 1, isoform CRA_a) (J3KND1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDRNPSPPPPGRDKEEEEEVAGGDCIGSTVYSKHWLFGVLSGLIQIVSPENTKSSSDDEEQLTELDEEMENEICRVWDMSMDEDVALFLQEFNAPDIFMGVLAKSKCPRLREICVGILGNMACFQEICVSISSDKNLGQVLLHCLYDSDPPTLLETSRLLLTCLSQAEVASVWVERIQEHPAIYDSICFIMSSSTNVDLLVKVGEVVDKLFDLDEKLMLEWVRNGAAQPLDQPQEESEEQPVFRLVPCILEAAKQVRSENPEWLDVYMHILQLLTTVDDGIQAIVHCPDTGKDIWNLLFDLVCHEFCQSDDPPIILQEQKTVLASVFSVLSAIYASQTEQEYLKIEKDLPLIDSLIRVLQNMEQCQKKPENSAESNTEETKRTDLTQDDFHLKILKDILCEFLSNIFQALTKETVAQGVKEGQLSKQKCSSAFQNLLPFYSPVVEDFIKILREVDKALADDLEKNFPSLKVQT
Protein: Zinc finger protein 354A (Transcription factor 17) (TCF-17) (Zinc finger protein eZNF) (O60765)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:23665872}.
Interaction partners:
- Transcription intermediary factor 1-beta
- Ubiquitin carboxyl-terminal hydrolase 50
- Protein FRG2-like-2
Sequence:
MAAGQREARPQVSLTFEDVAVLFTRDEWRKLAPSQRNLYRDVMLENYRNLVSLGLPFTKPKVISLLQQGEDPWEVEKDGSGVSSLGSKSSHKTTKSTQTQDSSFQGLILKRSNRNVPWDLKLEKPYIYEGRLEKKQDKKGSFQIVSATHKKIPTIERSHKNTELSQNFSPKSVLIRQQILPREKTPPKCEIQGNSLKQNSQLLNQPKITADKRYKCSLCEKTFINTSSLRKHEKNHSGEKLFKCKECSKAFSQSSALIQHQITHTGEKPYICKECGKAFTLSTSLYKHLRTHTVEKSYRCKECGKSFSRRSGLFIHQKIHAEENPCKYNPGRKASSCSTSLSGCQRIHSRKKSYLCNECGNTFKSSSSLRYHQRIHTGEKPFKCSECGRAFSQSASLIQHERIHTGEKPYRCNECGKGFTSISRLNRHRIIHTGEKFYNCNECGKALSSHSTLIIHERIHTGEKPCKCKVCGKAFRQSSALIQHQRMHTGERPYKCNECGKTFRCNSSLSNHQRIHTGEKPYRCEECGISFGQSSALIQHRRIHTGEKPFKCNTCGKTFRQSSSRIAHQRIHTGEKPYECNTCGKLFNHRSSLTNHYKIHIEEDP
Protein: Speckle targeted PIP5K1A-regulated poly(A) polymerase (EC 2.7.7.19) (EC 2.7.7.52) (RNA-binding motif protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (A0A0A8K9B1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MAAVDSDVESLPRGGFRCCLCHVTTANRPSLDAHLGGRKHRHLVELRAARKAQGLRSVFVSGFPRDVDSAQLSEYFLAFGPVASVVMDKDKGVFAIVEMGDVGAREAVLSQSQHSLGGHRLRVRPREQKEFQSPASKSPKGAAPDSHQLAKALAEAADVGAQMIKLVGLRELSEAERQLRSLVVALMQEVFTEFFPGCVVHPFGSSINSFDVHGCDLDLFLDLGDLEEPQPVPKAPESPSLDSALASPLDPQALACTPASPPDSQPPASPQDSEALDFETPSSSLAPQTPDSALASETLASPQSLPPASPLLEDREEGDLGKASELAETPKEEKAEGAAMLELVGSILRGCVPGVYRVQTVPSARRPVVKFCHRPSGLHGDVSLSNRLALHNSRFLSLCSELDGRVRPLVYTLRCWAQGRGLSGSGPLLSNYALTLLVIYFLQTRDPPVLPTVSQLTQKAGEGEQVEVDGWDCSFPRDASRLEPSINVEPLSSLLAQFFSCVSCWDLRGSLLSLREGQALPVAGGLPSNLWEGLRLGPLNLQDPFDLSHNVAANVTSRVAGRLQNCCRAAANYCRSLQYQRRSSRGRDWGLLPLLQPSSPSSLLSATPIPLPLAPFTQLTAALVQVFREALGCHIEQATKRTRSEGGGTGESSQGGTSKRLKVDGQKNCCEEGKEEQQGCAGDGGEDRVEEMVIEVGEMVQDWAMQSPGQPGDLPLTTGKHGAPGEEGQPSHAALAERGPKGHEAAQEWSQGEAGKGASLPSSASWRCALWHRVWQGRRRARRRLQQQTKEGAGGGAGTRAGWLATEAQVTQELKGLSGGEERPETEPLLSFVASVSPADRMLTVTPLQDPQGLFPDLHHFLQVFLPQAIRHLK
Protein: RE56164p (Q8IGP0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
HSVSGFRSIMLRPSSLQAVAIAIVLISSSASAEVVNFEPCPDSVDTCTIQQVRVSPCPEALNNAACNIRRKHNSEMSFDFTPNFDADTLVASLGWAKSENVELPLLTLDSAACKYTPCPVRSGVKQTYTTLVPIEAKFPLSPYTIRWALKDPVSQKRCCFTIDIKVVR
Protein: At1g10470 (Putative response regulator 3) (Q2HIV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MARDGGVSCLRRSEMMSVGGIGGIESAPLDLDEVHVLAVDDSLVDRIVIERLLRITSCKVTAVDSGWRALEFLGLDNEKASAEFDRLKVDLIITDYCMPGMTGYELLKKIKESSNFREVPVVIMSSENVLTRIDRCLEEGAQDFLLKPVKLADVKRLRSHLTKDVKLSNGNKRKLPEDSSSVNSSLPPPSPPLTISPESSPPLTVSTESSDSSPPLSPVEIFSTSPLSSPIDDEDDDVLTSSSEESPIRRQKMRSPGLD
Protein: Uncharacterized protein (Q57W10)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Complex 1 LYR protein domain-containing protein
- Uncharacterized protein
- FAD-binding domain-containing protein
- Complex 1 LYR protein domain-containing protein
- Uncharacterized protein
- NADH dehydrogenase 1 beta subcomplex subunit 7
- SET domain-containing protein
- Sulfotransferase
- Flavoprotein monooxygenase, putative
Sequence:
MTSQNPPPRPPPTTPAATPGGVQYNTRRESEAVAIEQRRQQQQRATDAQRRGEEPLPEQSESEMARWWPEENQNWSGRMFASPLDKNKKKFDGMFVPEMKEVHGPDKPLELSYAGDNFFLNPDFHMADEVFDETRRFVPPPSFDPAVDEIDDEGFVDGQVMFDIQKAVDEDRRRLEAFGNPLLVEDQVDYLLQPQREGQENIQQRQEFNGFVHWGLLHGAHMIIEENQDYKKAHEFVNRYMRDIDLFQKWLEHPKVRAHIQKKFGVDMHAKFDKLMALVMAMYARSKIQVYEDDPAGALKSLTACMSFINEGADLKKERHRKAIGAVLAARGMVYCKLKSYDRAEDDLTRALRFVNQKRCATLFQLRAEAREALGRIEEARLDEERAAEIWENAEVIAPGMSGKPYKFVL
Protein: Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (A1L2G3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q92560}. Nucleus {ECO:0000250|UniProtKB:Q92560}. Note=Mainly nuclear. Binds to chromatin. {ECO:0000250|UniProtKB:Q92560}.
Interaction partners:
- ASXL transcriptional regulator 2.
- ASXL transcriptional regulator 1.
- BRCA1-associated RING domain 1.
- Host cell factor C1b.
- Ubiquitin carboxyl-terminal hydrolase.
- Proteasomal ubiquitin receptor ADRM1
- Proteasome 26S subunit, non-ATPase 14.
- 26S proteasome non-ATPase regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 7
- Proteasome subunit alpha type
Sequence:
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQSPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDDIVNDMFFAHQLIPNSCATHALLSVLLNCSGVELGMTLSRMKAFTKGFNPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKDRLFELDGLKAYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYESKLDILKRNRQIILEGLQQIREKKVIRMTQQESGQDRKQQDSSSSEDTPPVVKKEEVQETPIPSGAEQATPTEAQEGAASLPSPAGKVRSMAKPALPAGGAPPPAPLPAPSTNTIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRPPQPPYSDDEDDYDDEEEECSTAGVTNSRVRRKLGLRTRTMSRTAVGGVAAMEGQLALSVLAEKLKKEVQRKDALATTGSTPLNVRTEGRTGGISITSACQPSPTPSNESTDTASEIGSAFNSPLRSPARSQATTRPSSPVASHVGRVLFGEEEGLPRLDARHNRAVRDLGVLVSSTQLQLQEDGVIFALPPTEALEGLKKVGGVDKKKKEEASGPGGEEEVKEGPSVEMKAEDVKESVDVKPEKENLPTTDVENSTKPPGEKYTPKELLALLKYVEADIANYEVYLKEEVEKRKKYKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ
Protein: Meiosis-specific nuclear structural protein 1 (Q61884)
Organism: Mus musculus (Mouse)
Function: May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly. May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:8032679}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:22396656, ECO:0000269|PubMed:37198331, ECO:0000269|PubMed:37295417, ECO:0000269|PubMed:37865089, ECO:0000269|PubMed:37989994}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q8NEH6}. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme. {ECO:0000250|UniProtKB:Q2KIQ2}.
Interaction partners:
- Cilia- and flagella-associated protein 276
- EF-hand domain-containing family member B
- Parkin coregulated gene protein homolog
- RIB43A-like with coiled-coils protein 2
- Tektin-3
- Tektin-1
- Tektin-2
- Cilia- and flagella-associated protein 45
Sequence:
MATKKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRFLRVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHAAKLLGYLPKGVFKREDDVDMLGEEFRKAYQKRDGV
Protein: Epithelial-stromal interaction protein 1 (Q96J88)
Organism: Homo sapiens (Human)
Function: Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity).
Interaction partners:
- Interferon-induced protein 44-like
- Interferon-induced GTP-binding protein Mx1
- Interferon-induced protein 44
- Protein mono-ADP-ribosyltransferase PARP9
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- Interferon-induced protein with tetratricopeptide repeats 3
- 2'-5'-oligoadenylate synthase 2
- Sterile alpha motif domain-containing protein 9-like
- E3 ISG15--protein ligase HERC5
- XIAP-associated factor 1
Sequence:
MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWGI
Protein: Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Q8AYI3)
Organism: Gallus gallus (Chicken)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173, ECO:0000256|RuleBase:RU362107}.
Interaction partners:
Sequence:
MAPYCVWLARLRHALNGGIRRYHVASVLCQRAKVAMSHFEPNEYINYEKLEKNINIVRKRLDRPLTLSEKIVYGHLDDPAKQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLSTAGAKYGVGFWKPGSGIIHQIILENYSYPGVMLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGKLSGWSSPKDVILKVAGILTVKGGTGAIIEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNTRMKKYLGKTGRADIAALADEFQQYLVPDAGCQYDQVIEINLSELKPHINGPFTPDLAHPVSDVGAVAEKEGWPVDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSKFTITPGSEQIRATIERDGYAQILRDVGGLILANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALSIAGTLKFNPETDFLTGADGKKFKLEAPDADELPRLDFDPGQDTYQYPPKDGSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDMLILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNALTQEFGPVPDTARYYKKMGVKWAVIGDENYGEGSSREHAALEPRHLGGRVIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLSIVGLADFAPGKPLKCIIKHPNGSQETIMLNHTFNESQIEWFQAGSALNRMKELQQKSS
Protein: PATJ crumbs cell polarity complex component (A0A2R8Y549)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cell junction, tight junction {ECO:0000256|ARBA:ARBA00004435}.
Interaction partners:
Sequence:
MPENPATDKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLNHIPSDCSANFDFSRKGLLVFTDGSITNGNVHRPSNNSTVSGLFPWTPKLGNEDFNSVIQQMAQGRQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIFVKDVQPGSVADRDQRLKENDQILAINHTPLDQNISHQQAIALLQQTTGSLRLIVAREPVHTKSSTSSSLNDTTLPETVCWGHVEEVELINDGSGLGFGIVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGNSVRMLVARDPAGDISVTPPAPAALPVALPTVASKGPGSDSSLFETYNVELVRKDGQSLGIRIVGYVGTSHTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHLTLVRRKTSSSTSPLEPPSDRGTVVEPLKPPALFLTGAVETETNVDGEDEEIKERIDTLKNDNIQALEKLEKVPDSPENELKSRWENLLGPDYEVMVATLDTQIADDAELQKYSKLLPIHTLRLGVEVDSFDGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVDEPRRTETSLPETEVDHNMDVNTEEDDDGELALWSPEVKIVELVKDCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVAERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAVPPGLVHLGICKPLVEDNEEESCYILHSSSNEDKTEFSGTIHDINSSLILEAPKGFRDEPYFKEELVDEPFLDLGKSFHSQQKEIEQSKEAWEMHEFLTPRLQEMDEEREILVDEEYELYQDPSPSMELYPLSHIQEATPVPSVNELHFGTQWLHDNEPSESQEARTGRTVYSQEAQPYGYCPENVMKENFVMESLPSVPSTEGNSQQGRFDDLENLNSLAKTSLDLGMIPNDVQGPSLLIDLPVVAQRREQEDLPLYQHQATRVISKASAYTGMLSSRYATDTCELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSLSSTPRVIPNVHNKANKITGNQNQDTQEKKEKRQGTAPPPMKLPPPYKALTDDSDENEEEDAFTDQKIRQRYADLPGELHIIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISSEEDGSVEVGIKQLPESESFKLAVSQMKQQKYPTKVSFSSQEIPLAPASSYHSTDADFTGYGGFQAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETVATILKCAQGLVQLEIGRLRAGSWTSARTTSQNSQGSQQSAHSSCHPSFAPVITGLQNLVGTKRVSDPSQKNSGTDMEPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVVADTNISAIAAQLENMSTGYHLGSPTAEHHPEDTETPPPKIITLEKGSEGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAADDGRLKRGDQILAVNGETLEGVTHEQAVAILKHQRGTVTLTVLS