wanglab/gogpt-training-data huggingface dataset:
Protein: Error-prone DNA polymerase (EC 2.7.7.7) (C1F5L7)
Organism: Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- UmuC domain-containing protein
- Beta sliding clamp
- DNA polymerase III subunit delta
- Protein RecA
- DNA polymerase III, delta prime subunit
- Uncharacterized protein
- DNA polymerase III subunit gamma/tau
- ImpB/MucB/SamB family protein
- DNA polymerase IV
Sequence:
MTDRYVELHAASAFSFLQAASQPEKLTDRAAEIAMPALALLDHNGLYGAARFHTAAQRNNIRAHIGAEIAVSSFGPRWLPPAWLPHQCKSEPTRIPLLCESREGYQNLCQLITRFKMREETKESGAATFDDLSEYASGLVCLTGGDEGPLAAALSSGGEAAGREAVEELTRIFGRGSVYVELQRHQDREEEWRNQAALRIARSLNLPVIATNGVRHATPYEREVLDLFTAIRNHIELDQAGRLLATNSQRHLRTASEMTALFRDIPGAVENTLVLSSRLGFQLHDLGYEFPRYPVPDGDTMDSFLRKRVEEGVLRRYAPKNDRGLMERAKKQVEHELTLIAKLGFAGYFLIVWDIIRFCQQHDILVQGRGSAANSVVCYCLEITAVDPVGMDLLFERFLSESRNEWPDIDLDLPSEEKREQAIQYVYRRYGELGTAMCANVITYREKSAARETGKALGFDEETLGRLSSLAGQWEWRGNTDTMAHTFHHAGFDIRHARIAKYIELSMRIQDLPRHLGQHSGGMVICQGHLNKVVPLERASMANRHVVQWDKEDCADLGIIKVDLLGLGMMAVLHDCLELIPRHYGNKVDLAQLPQDDEVYRVVQRADTVGMFQIESRAQMASLPRNCPRKFYDLVVQVAIIRPGPIVGQMMHPYMRRRQGKEAVTYPHPSLVPVLERTLGVPLFQEQLLRIAMTVADFSGAEADELRRAVGMRRSWERMKNLEGNLRAGMTRNGIDERTQDTIVQQISSFALYGFPESHAASFALIAYASAYLKVKYLAAFTAAILNNQPMGFYSPAVLVKDAQRHGLRVKPIDVQVSEWRCTVEHESDGGLALRIGLGYARQLKRESAEALVRSRLQDGPFRSVEDVAQRVPFLNRKELKRLAEIGALNQLQGIEHRRDALWQIERAGKLEGPLLANAESLREDSEARPLQQMNVEERLVADYAGTGLTVGRHPMHYRRAELRRANILSAQDLRQRRDGEYVRVAGCIIARQRPGTAKGFIFISMEDETGICNVIVTPDLYDRDRLVVTRSKFLLVEGPLQNQDSVIHIKATRLTSLTDFALDVSSHDFH
Protein: GS homeobox 1 (Homeobox protein GSH-1) (P31315)
Organism: Mus musculus (Mouse)
Function: Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the transcription of the GHRH gene. Plays an important role in pituitary development.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MPRSFLVDSLVLREASDKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGAGAGAGGGAPQGCKCSSLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP
Protein: cDNA, FLJ96114, highly similar to Homo sapiens bromodomain and WD repeat domain containing 2 (BRWD2), mRNA (B2RCJ6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSEGIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAEFITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFSMVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQNKLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKNIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEPVWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKKLLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLFQEKSASTTAPKEAAPRDKLSNPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAMQLLLETSADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADACRYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSVAETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFASKAGAAGKDLLNELESPKEEPIEE
Protein: Monosaccharide transporter (Q8J0V1)
Organism: Aspergillus niger
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAEGFVDASRVEAPVTLKTYLMCAFAAFGGIFFGYDSGYISGVMGMRYFIEEFEGLDYNTTPTDSFVLPSWKKSLITSILSAGTFFGALIAGDLADWFGRRTTIVSGCVVFIVGVILQTASTSLGLLVAGRLVAGFGVGFVSAIIILYMSEIAPRKVRGAIVSGYQFCITIGLMLASCVDYGTENRLDSGSYRIPIGLQLAWALILGGGLLCLPESPRYFVKKGDLAKAAEVLARVRGQPQDSDYIKDELAEIVANHEYEMQVIPEGGYFVSWMNCFRGSIFSPNSNLRRTVLGTSLQMMQQWTGVNFVFYFGTTFFQSLGTIDDPFLISMITTIVNVCSTPVSFYTIEKFGRRSLLLWGALGMVICQFIVAIVGTVDGSNKHAVSAEISFICIYIFFFASTWGPGAWVVIGEIFPLPIRSRGVALSTASNWLWNCIIAVITPYMVDKDKGDLKAKVFFIWGSLCACAFVYTYFLIPETKGLTLEQVDKMMEETTPRTSAKWTPHGTFTAEMGLTANAVAEKATAVHQEV
Protein: 4,4'-diaponeurosporen-aldehyde dehydrogenase (EC 1.2.1.-) (4,4'-diaponeurosporenal dehydrogenase) (Q2FWX9)
Organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)
Function: Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. Catalyzes the oxidation of 4,4'-diaponeurosporen-4-al to yield 4,4'-diaponeurosporenoic acid.
Interaction partners:
- Aldehyde-alcohol dehydrogenase
- Phosphate acetyltransferase
- Formate acetyltransferase
- Alcohol dehydrogenase
- Glutamate synthase, large subunit, putative
- (S)-3-amino-2-methylpropionate transaminase (GABA aminotransferase) (Gamma-amino-N-butyrate transaminase) (L-AIBAT)
- Putative aldehyde dehydrogenase AldA
- Putative aldehyde dehydrogenase
- 1-pyrroline-5-carboxylate dehydrogenase
- Glutamate dehydrogenase
Sequence:
MNIIEQKFYDSKAFFNTQQTKDISFRKEQLKKLSKAIKSYESDILEALYTDLGKNKVEAYATEIGITLKSIKIARKELKNWTKTKNVDTPLYLFPTKSYIKKEPYGTVLIIAPFNYPFQLVFEPLIGAIAAGNTAIIKPSELTPNVARVIKRLINETFDANYIEVIEGGIEETQTLIHLPFDYVFFTGSENVGKIVYQAASENLVPVTLEMGGKSPVIVDETANIKVASERICFGKFTNAGQTCVAPDYILVHESVKDDLITALSKTLREFYGQNIQQSPDYGRIVNLKHYHRLTSLLNSAQMNIVFGGHSDEDERYIEPTLLDHVTSDSAIMQEEIFGPILPILTYQSLDEAIAFIHQRPKPLSLYLFSEDENATQRVINELSFGGGAINDTLMHLANPKLPFGGVGASGMGRYHGKYSFDTFTHEKSYIFKSTRLESGVHLPPYKGKFKYIKAFFKN
Protein: Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine-protein kinase RIPK2) (Q4V958)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR037921}.
Interaction partners:
Sequence:
MSRNMEHTGCVNICSLTSTLPVIPYRKLTDLHYISKGGFGTVFRAQHSDWRTTVAIKCLKLDSPVGERERNCLLKEAEVLHKARFNHIIQIFGVCNEPEFFCIITEYMTNGSLDELLHEKDIYPAVAWPLRLRILYEIALGVNFLHNMSPPLLHHDLKTQNILMDGEYHVKIADFGLSKWRQLSITKGSGSKPAEMGGTVIYMPPEEYEPSKTRRTDVKYDMYSYAIIMWEVLSRRIPFEEATNPMQIMFSVLRGARPDTGLDSLPVDIPSRETLINLMTSGWTANPDERPSFLHCLIELEPMLRRFDEIDVLEAVLEVKRIKYRRPSSCCSSTQSNGKKIEEKCVKELNVPWPDNSSTSGSGSCSSQEAEISQPGFLTISTPSQGAYAGLPSSLMSLPLDPPKPLMDNCSPNNLSPEYQTAQVVSDLNIPFKAHAPHSESELALAIQPLTLHPHPQDFVTAFDDQGPAARWIAARREEVVRQMTEACLNQSLDALLSRELLMREDYELVVNQTTRTAKVRKLLDTCERHSEEFCRVVVRKLQDNKQMGLQPYPDLSTTSSPPSPYVAPSAPFLSNSFNNTRNF
Protein: UPF0664 stress-induced protein C29B12.11c (O14032)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome b-c1 complex subunit 7
- Cytochrome b-c1 complex subunit 8
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Probable mitochondrial-processing peptidase subunit beta
- Cytochrome b-c1 complex subunit 9
- Cytochrome b-c1 complex subunit 10
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase polypeptide 5, mitochondrial
- Cytochrome c oxidase subunit 4, mitochondrial
Sequence:
MSINWVTYKEGSESDILLLENECMFDCFDGVAISILCKPPSLKSWTCTKGLLCLTNQRLVYIAKDTDCDFKDFQSPVANLKDTKLNQPFFGANYYSGTVMPVPNGGIPCEAEVKLQFNEGGIFNFVEAWNRLIQRFQEVDSVSRVQHLDPLPPYHRPSSSQDQPPHYEEAVNKS
Protein: Simjang, isoform D (M9PET3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAKMEVDDVVDLSLGSGRDPALTITPAPPPAALSNRDLRALTANNAGLTITPSASPATNNGTTSNSSNTNSNSSSTTTTTNNNNNSSSNTNSSSANNNNNNNSINASDGVTGATSGSIGGGQDENKVQRRVLRPRTEPKSYAEAPDIVLLPARTNGRQQNGNIDSETDDEEMPPYVPIKELSHAELKEREKSLRKLRQDLRNEETKLMLLKKLKQSQQVMKENLVVTPTSVSPNNPLSAIPAALTSKGSLSVTPTSAVPLPAHSKGSRSSLSGSGGPAVSISATNSRTGSSSSAAAAASAIAAAAMSGQHRSGSNSILPPPRSSLPAGATLAAGTTITPATSSSHRSSNLPPRTNLPNLTITPSVTITPTSAPPSSLKPRNPNISDNSKVPGTISNSVSITPALPLSQSHQNQHNDQKNDRSTPREDAQTPAQRQAAAKMALRKQLEKTLLQIPPPKPPPPEMHFIPNPSNTDFVYLLGLETVVDYLTVNKKANAVAAPFRCAQCKIDFTPVWKWEKQTNKDPKVICEQCVTSNVKKALKAEHTNRLKQAFVKALQQEQEIEQRLASQSSPSPVDNHGSSGGGNSLSVSAVSSNSSSSHMQREREQLQASHASAAAALVNLPPSVTVIPTKCQTPTPATPRPTPPPPQSQATPPPSSGGSRSSRAAATAAAAAIAAQQAGILSPGPSPAHHHEPTTSSRSSRNDRLDHHHQSQQQQQRDQRERDQQQRDQQSQQQAQNYDKYSAATLAAAAHLSALGGMGGLNINSLASLGNLGNLGNLSQLGNLAALGGLGNFGGASTGSANPAAGLSGSSPAATAAAMQAFQQQLFRALGQGLGGNPQHMMQFAPLLYSYQMAMAQAAQVAAFNNNNKKSSSSSGSAKNSSSSNSMAEVQRAAELQRQYLLEMIPPQQQSGASGSRQNNWKA
Protein: At1g67350 (F1N21.17) (NADH-ubiquinone oxidoreductase) (Q9FYF8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Excitatory amino acid transporter
- At4g16450
- NADH dehydrogenase 1 alpha subcomplex subunit 8-B
- NADH dehydrogenase 1 beta subcomplex subunit 10-A
- NADH dehydrogenase 1 alpha subcomplex subunit 13-A
- NADH dehydrogenase 1 beta subcomplex subunit 10-B
- ESSS subunit of NADH:ubiquinone oxidoreductase
- NADH dehydrogenase iron-sulfur protein 5-A
- NADH dehydrogenase 1 beta subcomplex subunit 2
- Transmembrane protein
Sequence:
MGFIMEFAENLVLRLMENPEERDRKAREHIYEMHERCKKIKEMWALPIRPYGFWTFERHNAQLRWDPQISQVAGRRDPYDDLLEDNYTPPSSSSSSSD
Protein: Protein CMSS1 (Cms1 ribosomal small subunit homolog) (Q9BQ75)
Organism: Homo sapiens (Human)
Interaction partners:
- Protein LTV1 homolog
- Ribosome biogenesis protein NOP53
- Bystin
- Zinc finger CCCH domain-containing protein 11B
- rRNA-processing protein UTP23 homolog
- MKI67 FHA domain-interacting nucleolar phosphoprotein
Sequence:
MADDLGDEWWENQPTGAGSSPEASDGEGEGDTEVMQQETVPVPVPSEKTKQPKECFLIQPKERKENTTKTRKRRKKKITDVLAKSEPKPGLPEDLQKLMKDYYSSRRLVIELEELNLPDSCFLKANDLTHSLSSYLKEICPKWVKLRKNHSEKKSVLMLIICSSAVRALELIRSMTAFRGDGKVIKLFAKHIKVQAQVKLLEKRVVHLGVGTPGRIKELVKQGGLNLSPLKFLVFDWNWRDQKLRRMMDIPEIRKEVFELLEMGVLSLCKSESLKLGLF
Protein: Proline rich 14 (H3BND2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLS
Protein: Islet amyloid polypeptide (IAPP) (Amylin) (Diabetes-associated peptide) (DAP) (P12969)
Organism: Rattus norvegicus (Rat)
Function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P10997}.
Interaction partners:
- Calcitonin receptor
- Calcitonin gene-related peptide type 1 receptor
- Receptor activity-modifying protein 1
- Pro-adrenomedullin
- Receptor activity-modifying protein 3
- Receptor activity-modifying protein 2
- Calcitonin gene-related peptide 2
- Insulin-degrading enzyme
- Insulin-2
- Insulin-1
Sequence:
MRCISRLPAVLLILSVALGHLRATPVGSGTNPQVDKRKCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYGKRNVAEDPNRESLDFLLL
Protein: Basic leucine zipper 24 (AtbZIP24) (bZIP protein 24) (Q8GTS1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor involved in the regulation of salt stress response. Functions as a negative transcriptional regulator of salt stress acclimation response by regulating cation homeostasis. Regulates negatively the expression of genes contributing to ion and osmotic homeostasis during salt stress, such as the Na(+) transporter HKT1, the Na(+)/H(+) antiporter SOS1, the aquaporin PIP2-1 and the glutamine synthetase GLN1-3. In addition, targets genes with functions in plant growth and development, such as argonaute 4 (AGO4) and cyclophilin 19 (CYP19).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:18703123, ECO:0000269|PubMed:19248824}. Cytoplasm {ECO:0000269|PubMed:18703123, ECO:0000269|PubMed:19248824}. Note=Targeted to the nucleus in salt stress conditions. {ECO:0000269|PubMed:19248824}.
Interaction partners:
- Basic leucine zipper 8
- bZIP transcription factor 17
- At5g15830
- Basic leucine zipper 1
- TPR repeat-containing protein ZIP4
- Basic leucine zipper transcription factor
- bZIP transcription factor 2
Sequence:
MFCCCKDCRGNQRVSNFDSLTGVFFGDLEFGPQNQRYIKMNEEEDKDQDRVTRGCSHTHSCNPPGPEDASHSHTCFHAHTHLIISDQQENDHSDSSNKKRLCGNREAVRKYREKKKARTAYLEDEVMRLQSLNEQFLRKLQSQEMVETELIRLRALLVEMQGKIEVELCSFSFQKQCNGSGFVFKEDGCNLATSNMMCEAARVECEEGQTLHDPIQSFVPQPPPFSR
Protein: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (Complex I-AQDQ) (CI-AQDQ) (NADH-ubiquinone oxidoreductase 18 kDa subunit) (Q9CXZ1)
Organism: Mus musculus (Mouse)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:38575788}; Peripheral membrane protein {ECO:0000269|PubMed:38575788}; Matrix side {ECO:0000269|PubMed:38575788}. Note=The interaction with BCAP31 mediates mitochondria localization. {ECO:0000250|UniProtKB:O43181}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 1
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 4
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase flavoprotein 3, mitochondrial
Sequence:
MAAVSISVSLRQAMLGRRAMATAAVSVCRVPSRLLSTSTWKLADNQTRDTQLITVDEKLDITTLTGVPEEHIKTRKVRIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWASTADPLSNMVLTFSAKEDAIAFAEKNGWSYDVEEKKVPKPKSKSYGANFSWNKRTRVSTK
Protein: Upstream stimulatory factor 2 (Major late transcription factor 2) (Upstream transcription factor 2) (Q64705)
Organism: Mus musculus (Mouse)
Function: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Subcellular location: Nucleus.
Interaction partners:
- Upstream stimulatory factor 1
- Transcription factor Sp1
- Histone acetyltransferase p300
- Mediator of RNA polymerase II transcription subunit 1
- Breast cancer type 1 susceptibility protein homolog
Sequence:
MDMLDPGLDPASSATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAIASVQQAAFGDHNIQYQFRTESNGGQVTYRVVQVTDGQLDGQGDAAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPTGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCHADNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGESTRQ
Protein: Lycopene beta-monocyclase (Q7WT70)
Organism: Flavobacterium sp. (strain P99-3)
Interaction partners:
Sequence:
MDNHYDIAIIGMGCAGSHVVLQLLENAPHLKVAILDPYGSLTQEKTWSFWEKGPGKYDDLIIASWKKCRFHTGDEELSLTMNPYLYKSIENVKFSAFAKAQLQQNSKYHYIGSEVTHLEQTHNSKEVTVSYNNGSLTADLVLDSRPLEGIPSTGITLLQHFKGWFIETSEDYFDPKEFTKMDYQLVDPGTTSFVYILPFSKRKALVEYTYFAKNLVQDDVYDQYLDTYITDFLKISDYKITKVEKGIIPMTSHDFKPFKNKNVIKIGTAGGWVKASTGYSFKNSERLARQLVNNYLENRPLSYKMTNKKYEVFDETLLRVLHENEASGPEIFSKMYQRNSAQNIMAFLDEESSLLAELGIMKSLTSWPFVKNFFKSL
Protein: Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog) (Q5TB80)
Organism: Homo sapiens (Human)
Function: Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Nucleus. Note=Localizes to the distal end of centrioles throughout the cell cycle. During ciliogenesis, found at the cilia base. Localizes to spindle microtubules during mitosis.
Interaction partners:
- Centrosomal protein of 290 kDa
- Tubulin gamma-1 chain
Sequence:
MANCSQEELDEEFEQFMKELSDDSFENSDKTARQSKKEMKKKDTVPWWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY
Protein: Troponin I, slow skeletal muscle (A0A060Y0V6)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Troponin T type 2b
- Uncharacterized protein
- Troponin T, slow skeletal muscle
- Uncharacterized protein
- Troponin T type 3a
- Troponin T2e, cardiac
- Uncharacterized protein
- Troponin C, slow skeletal and cardiac muscles
- Troponin T, slow skeletal muscle
- Troponin C, slow skeletal and cardiac muscles
Sequence:
MADAPKPKEKSKISSARRLGLKIRLLIVAGQMLEVEVEEKKRERDEALAERVPPLKLSGLSVEELQDLCRDLHHKIDVVDEERYDVGLKVTKNDKEIHNLGLKIIELQSKFKKPNLKRVKISAEAMLSVLLGSKHKETIDFKSNLKTVKKPEEKKEEVTDWRQNVDAMSGMEGRKKMFDA
Protein: GDP-mannose 4,6-dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (P72586)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- GDP-L-fucose synthase
- dTDP-4-dehydrorhamnose reductase
- Glucosyltransferase
- Mannose-1-phosphate guanyltransferase
- mannose-1-phosphate guanylyltransferase
- Slr0583 protein
- GDP-mannose 4,6-dehydratase
- Spore coat polysaccharide biosynthesis protein SpsC
- Perosamine synthetase
- UTP--glucose-1-phosphate uridylyltransferase
Sequence:
MSKSKVVLLTGITGQDGSYLSELLLEKGYQVHGIIRRTSTFNTDRIDHLYVDPHDLEAKLRLHYGDLTDGTTLRRILEDVKPTEIYNLGAQSHVRVSFDSPEYTVDSVAMGTLRLLEAIRDYQHRTGIQVRFYQAGSSEMFGKVQEIPQKETTPFYPRSPYACAKVYGHWQTVNYRESYDLFACNGILFNHESPRRGETFVTRKITRAIARIVAGTQKKLYLGNIDSKRDWGYAKDYVRAMWAMLQQEQPDDYVVATGETHEVKEFLEIAFGYVNLNWQNYVAFDERYLRPAEVDLLIGDPAKTKAQLGWEPSVTFTELVHLMVEADLAVLGLTSPNQSGRIKELMAQDMAFIRSQNGHAVD
Protein: Rho-GAP domain-containing protein (H2KZS7)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEHNDFRVVTSSSVYRKGSTTTAGAAAAGPKSNKLSYTLGEVCSTNVTLDVNVGTGWTRIRLKEVPKFIVHAFNIISKHGMDTDGIFRKEGNSVRLNRAEVQAIYKGQSDIPNDYSVIDVCTMVKRFLRDLKPPLLDSEECRARLLKKACQARISDSFLMTRDEMADIFYLEDRTIEQQTPLLSDVHASTLGYVMRQLYREIEHSQRVETSMSGRLSAMSQSSLRSSNDTHQSSSDRFSDVSDLRNAAFSESTSDSALSTPTATPTTSRVSTNDAAAAAAAAQHF
Protein: Uncharacterized protein (Q584E7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Multifunctional methyltransferase subunit TRM112
Sequence:
MEGERGRNSQNQKLGLELVHDDGRPIASCPIDMNELLKKMGKTVEVKEGVRVRLEEYNEDEGLYYSEDSWSEESEEESQSEENDSAEDIAETPPPGCRRVEDWNSAVRATQRGEKPPMVQASGILSRSPKHVKEKGTADIKAGQIPRRELWVSRAPPADTERTYKRLQTVRLMPCPTSRRFCLPPLTFHAAASYTGNAARGPRMLVYGGTTNLGKTTENELYEFSLLSGDWRRVEGKQSHSPGVYGHTAVVLKKHRRVVLTGGVGYGGVPPEPLESLTDDYRRARFHLLFPHKEPIQSNAQAIPETVANTELPTLWTLAHAAESVPTFGFLPVIFDVDLRTRRWRTIETSPKLPVVFHSAVAIGTRLYIFGGMNTHLQVSSQLILVDGETYKISLIPPSTDPPKARFLHSAVVYAHWMIIYGGFDAHNQPLDDAWAFDTVNERWEQLHCHGSHARGAHAACVVGSRLIVVGGFDSSFDGDEAPASTCLELNLIPNHEDKHLWRPLPLHPTVPPVAFAAVCPCGDDASFLLYGGCIAAKKGDDSKKAQGGGGKSPGRGRHTNSGHTGYSDCIGDDGDNLTIWKRLVPSNEGFLLTFPVKRPEKNNEGDAEPRYNALGVEIDPDEVPAEFLAFVKRQHDFLLKKTGNVEQTMKKIFLEERESMEPHLYLTPDEVERLIEESEELCTRFSEYKMEELPPHVPERQLRLHLNEECVSLSRQVRDVIKSMKGNPAAAAAVKSKTHRFKVGQKFESHSAPKPFRRVVIMSLMKEIKRNIKRVLLSNKALKTVEWPNKAEYLEAIRRMQETADTFLLSVKEILDVYIEKRVDSLVSAIDTRKNKLKRLTEAVERSRQSFPVHPLDIVARVGGRGGRSSPSPQSISSRARSRSPSARHFKGGEEATHTLNKGEVGVLLNKASAVRTNASLFGESCQSMIPPAPKQVATALLVPGMTPPPEGEDAAASRETVWHTACGQVQQIVKCVDRFIEGIRASQLEQKPLNEAGDGTEEGSYRVNLALATVWPLETCKDKLDELKKGMPEVRNPSPAAGGDEAAKLKKTQQHYTRLSKSLTALVQSVKMSILSRAGAKPPPAVHITSRDVVAASPSSKGRAWRPPQSRRQRSTIEVLDLHADDATEPEGYSPTAEEEQRHCHAVLSPLSPKLVPIEDLFASPRTAPAVEAPNRIPITSREAAALVSAPQAAVAATGECVIVPSKKDVRVVKNSSSASLLFHEGDDTSAAMHSRLFPPQAYHDYYAAAATPQQPTCIAVSNGPKMVAAGENRSSDAVISLIDVFDGVHPVTVTDEGKQDLKAMVSVTPGFFHAHPSAVDTGTSETSDHVKYCDSPMLEDDYFFFGRRLESSCLPTGPVQPLSTPSAKGTTRKKTQKREPSVKLAAKSRTRDTKSSPHCLSFSATPLRDSKRRSVSRGERAVRQLMEPDSFARGGGGGPLRGKLTPGEARIAEARKRGSLMSGS
Protein: Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2) (Q9JHW2)
Organism: Mus musculus (Mouse)
Function: Has omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively. Can also hydrolyze gamma-monomethyl-alpha-ketoglutarate in vitro.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9NQR4}.
Interaction partners:
- Glutamate dehydrogenase 1, mitochondrial
- D-aspartate oxidase
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase, mitochondrial
- L-amino-acid oxidase
- Putative aspartate aminotransferase, cytoplasmic 2
- Amine oxidase
- Amine oxidase
- Spermidine synthase
- Malate dehydrogenase, mitochondrial
Sequence:
MSTFRLALIQLQVSSIKSDNLTRACSLVREAAKQGANIVSLPECFNSPYGTTYFPDYAEKIPGESTQKLSEVAKESSIYLIGGSIPEEDAGKLYNTCSVFGPDGSLLVKHRKIHLFDIDVPGKITFQESKTLSPGDSFSTFDTPYCKVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRARAVDNQVYVATASPARDDKASYVAWGHSTVVDPWGQVLTKAGTEETILYSDIDLKKLAEIRQQIPILKQKRADLYTVESKKP
Protein: Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2) (N-hydroxyarylamine O-acetyltransferase) (EC 2.3.1.118) (Polymorphic arylamine N-acetyltransferase) (PNAT) (P11245)
Organism: Homo sapiens (Human)
Function: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Subcellular location: Cytoplasm.
Interaction partners:
- Cytochrome P450 1A2
- Cytochrome P450 2E1
- Xanthine dehydrogenase/oxidase
- Cytochrome P450 2A6
- Liver carboxylesterase 1
- Arylamine N-acetyltransferase 1
- Myeloperoxidase
- Arylacetamide deacetylase
- Cytochrome P450 2D6
- Glutathione S-transferase Mu 1
Sequence:
MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLRNIFKISLGRNLVPKPGDGSLTI