wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger protein 532 (Q9HCE3)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- MYND-type zinc finger-containing chromatin reader ZMYND8
- Bromodomain-containing protein 4
- NUT family member 1
- Histone-lysine N-methyltransferase NSD3
- Bromodomain-containing protein 3
Sequence:
MTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHMKQNAHGEDDSHAPSSSDVGVSVIVKNVRNIDSSEGGEKDGHNPTGNGLHNGFLTASSLDSYSKDGAKSLKGDVPASEVTLKDSTFSQFSPISSAEEFDDDEKIEVDDPPDKEDMRSSFRSNVLTGSAPQQDYDKLKALGGENSSKTGLSTSGNVEKNKAVKRETEASSINLSVYEPFKVRKAEDKLKESSDKVLENRVLDGKLSSEKNDTSLPSVAPSKTKSSSKLSSCIAAIAALSAKKAASDSCKEPVANSRESSPLPKEVNDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTPAIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASAAVLSSPPRAPLQSAVVTNAVSPAELTPKQVTIKPVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQATSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYIPNLSPPANAGITLPTRGYKCLECGDSFALEKSLTQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVSPSSNTSTSTSTLQSPVGAGTHTVTKIQSGITGTVISAPSSTPITPAMPLDEDPSKLCRHSLKCLECNEVFQDETSLATHFQQAADTSGQKTCTICQMLLPNQCSYASHQRIHQHKSPYTCPECGAICRSVHFQTHVTKNCLHYTRRVGFRCVHCNVVYSDVAALKSHIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGIKIGEPKIIYKCSMCDTVFTLQTLLYRHFDQHIENQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINLPLSIKPATQNSANQNKEDTKSMNGKEKLEKKSPSPVKKSMETKKVASPGWTCWECDCLFMQRDVYISHVRKEHGKQMKKHPCRQCDKSFSSSHSLCRHNRIKHKGIRKVYACSHCPDSRRTFTKRLMLEKHVQLMHGIKDPDLKEMTDATNEEETEIKEDTKVPSPKRKLEEPVLEFRPPRGAITQPLKKLKINVFKVHKCAVCGFTTENLLQFHEHIPQHKSDGSSYQCRECGLCYTSHVSLSRHLFIVHKLKEPQPVSKQNGAGEDNQQENKPSHEDESPDGAVSDRKCKVCAKTFETEAALNTHMRTHGMAFIKSKRMSSAEK
Protein: Cyclin D, isoform D (Cyclin D, isoform E) (Cyclin D, isoform F) (Q7KUZ5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- cyclin-dependent kinase
- Dacapo
- Cyclin-dependent kinase 2
- Retinoblastoma family protein
- Cyclin-dependent kinase 1
- Transcription factor E2f1
- RE32990p
- Cyclin-dependent kinase 5 homolog
- S-phase kinase-associated protein 2
- histone deacetylase
Sequence:
MDLLCSEIIVYESDPSLYRLNKRQQQMSSPAIIRDQSSICSSLGDAESDSHPDAQNNAVVCNMKELVYIYASVDSAAKNPEQLEPPPPPPPPPPPPPTATQSIQSYPRYISQEPPTSHCQRLDERLTTTADPPATDNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKDITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGLKWHLRSGHNLHFLLSLMTDLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLPLPKAPAECVEQHQQQHNFGSAAPHRTHTCKMQAQAQAQNEIQDVTF
Protein: Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase) (A0A8I6A7H6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03125}.
Interaction partners:
Sequence:
MWPGGERSSSVKVTFWAALRRLAPNPGLKVHNGKTGDSGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYKLNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHLGVAVKWVGVGKSRESMIQLF
Protein: Putrescine N-methyltransferase 4 isoform X2 (Putrescine N-methyltransferase 4 isoform X3) (A0A1U7XAI2)
Organism: Nicotiana sylvestris (Wood tobacco) (South American tobacco)
Interaction partners:
Sequence:
MEVISTNTNGSTIFKNGAIPMNGHQSGTSKHLNGYQNGTSKHQNGHHNGTSEHRNGHQNGISEHQNGHQNGTSEQQNGTISHDNGNELLGNSNSIKLGWFSEFSALWPGEAFSLKVEKLLFQGKSDYQDVMLFESATYGKVLTLDGAIQHTENGGFPYTEMIVHLPLGSIPNPKKVLIIGGGIGFTLFEMLRYPTIEKIDIVEIDDVVVDVSRKFFPYLAANFNDPRVTLVLGDGAAFVKAAQAGYYDAIIVDSSDPIGPAKDLFERPFFEAVAKALRPGGVVCTQAESIWLHMHIIKQIIANCRQVFKGSVNYAWTTVPTYPTGVIGYMLCSTEGPEVDFKNPINPIDKETTQVKSKLAPLKFYNSDIHKAAFILPSFARSMIES
Protein: Myosin regulatory light chain sqh (Myosin regulatory light chain, nonmuscle) (MRLC-C) (Protein spaghetti-squash) (P40423)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for cytokinesis, could regulate contractile ring function.
Interaction partners:
- Myosin heavy chain, non-muscle
- Myosin-2 essential light chain
- LD46604p
- Ras-like GTP-binding protein Rho1
- Protein phosphatase 1 regulatory subunit 12B
- Serine/threonine-protein phosphatase beta isoform
- Myosin light chain alkali
- Rho-associated protein kinase
- Serine/threonine-protein phosphatase alpha-2 isoform
- Ras-related protein Rac1
Sequence:
MSSRKTAGRRATTKKRAQRATSNVFAMFDQAQIAEFKEAFNMIDQNRDGFVEKEDLHDMLASLGKNPTDDYLDGMMNEAPGPINFTMFLTLFGERLQGTDPEDVIKNAFGCFDEENMGVLPEDRLRELLTTMGDRFTDEDVDEMYREAPIKNGLFDYLEFTRILKHGAKDKDEQ
Protein: Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) (O15270)
Organism: Homo sapiens (Human)
Function: Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P97363}; Single-pass membrane protein {ECO:0000250|UniProtKB:P97363}.
Interaction partners:
- Serine palmitoyltransferase 1
- ORM1-like protein 3
- Serine palmitoyltransferase small subunit A
- Serine palmitoyltransferase small subunit B
- 3-ketodihydrosphingosine reductase
- ORM1-like protein 1
- ORM1-like protein 2
- Serine palmitoyltransferase 3
- Alpha-1-acid glycoprotein 1
- Palmitoyltransferase ZDHHC9
Sequence:
MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQNGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED
Protein: C-type lectin domain family 4 member G (Liver and lymph node sinusoidal endothelial cell C-type lectin) (LSECtin) (Q6UXB4)
Organism: Homo sapiens (Human)
Function: Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner, in vitro.
Subcellular location: Cell membrane; Single-pass type II membrane protein {ECO:0000269|PubMed:14711836}.
Interaction partners:
- Lymphocyte activation gene 3 protein
- CD44 antigen
- Butyrophilin subfamily 3 member A3
- C-type lectin domain family 1 member B
- Paired immunoglobulin-like type 2 receptor alpha
- GTP-binding protein 1
Sequence:
MDTTRYSKWGGSSEEVPGGPWGRWVHWSRRPLFLALAVLVTTVLWAVILSILLSKASTERAALLDGHDLLRTNASKQTAALGALKEEVGDCHSCCSGTQAQLQTTRAELGEAQAKLMEQESALRELRERVTQGLAEAGRGREDVRTELFRALEAVRLQNNSCEPCPTSWLSFEGSCYFFSVPKTTWAAAQDHCADASAHLVIVGGLDEQGFLTRNTRGRGYWLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWICEKRHNC
Protein: Variant SH3 domain protein (Q9N415)
Organism: Caenorhabditis elegans
Interaction partners:
- Rab-3-interacting molecule unc-10
- Liprin-alpha
- Phorbol ester/diacylglycerol-binding protein unc-13
- Ras-related protein Rab-3
- TspO/MBR family protein
- ELKS/RAB6-interacting/CAST family member 2
- PID domain-containing protein
- Voltage-dependent calcium channel type A subunit alpha-1
- C2 domain-containing protein
- ATP-grasp domain-containing protein
Sequence:
MLGGLSGPGPPPPPPPASSYGMVPGPSTSFTNHLGPTTSSASTVPPTSDALLLQLRSRPNSRVFRALFQYLPLRDSPNENPQLELSLQPGDVVLVKGEMDSDGFYCGETLDGRQGLVPSNYVERVPDSVLLANARAPSPSFPLRIPQHFSTITHDFSSPDHSTLPDSVCPYPPADVTKVTVQEIKNNETPRIPCPRELIVEKKLSRSALVSWSSPEESFVAVSQYHVCVDGTVRAIVPGSYKCRALVEDIPLESSVNLSVRAVTEHGHSPDACCTIAIGNEAQVAPQQVRVWQVTPVSAYVRWYPSNSNAEHVVSLNAVKVGVCPPTVFQVQLHGLQPSTIYRVSVRTKHPKAVLEQRPVERCVDFKTLPKIGLPDPPSNVQVEGGAQPGTLLVSWIPVTNQPKPPSRAAVASYLVYADGKNIAQVPQATADHVVLRLADLSDDPPVFITVRTKTKEGAVSSDSNVTRVPRNQNAAPPPPPPPPTQIGNQSIIPVVDPSRLPLVDMTSSYPSYQQQQTLTNSMYMPIVTSTGAAVPLTNGHHHVATSAPSSAPFTAPARMIGATGLMSYQPTSYAANLQNSMQQSAPNSGHSGYATFDRSASLGAQPQATSILLGGGAAPRPSSVGQNQSAWKAQQPAQMSQYYTFHPSFLHTEPSGANEPRPSVLEMENSYLMRHRQAADHWASAPDARARIEAYSRGLARAGSADDRMVPMSTRQQPQLQRLIAAGSRAPLARVKSETGGFGTRSEPDLRPPTLDSDECRWFVALFDYTAAMSPNPNAEFEELQFRKHQLIKVYGGQDIDGFYHGAIGQRVGLVPSNMVIEIASDDIGKRRTTTNPAPPPPTAPEPALRRQRWGSLKSRSYDYAGEGRAPRERPHHPNYVSLDRRDDRDRDREGRYRRAGSSYEYRRLPEREKEYEGTYRRRQLETRDPRDPRDPRDDGYEDEGYRDKYRDRYDRRHPMDREREPRYPPYEPPYRGEKYEKYRERPRMEDMEFPSNGPHGSAQQQPHSLQNGPRNTYGMDQMTQQMSHMSTQGSMAQGSMGQGSMSQGPIGIPSSSGIGGMGGAGNQEMYMNGGMGTMGTSMTSQAAAASGAQKMARMVAKFDYDSRQLSPNVDAEQVELSFRQGDIIIVLGDMDEDGFYMGELNGLRGLVPSNFLQPQPLNNLLPSQPTEPMRKGVAFSDTQQMMRKPIRQSSQTSAGPSQGSSGGLAGAVASAAAASGGIKPVAKKSSAGSAGAGAKPLTKKTSDVGKSSAPNARKTSTAVKKADTGAKKKG
Protein: Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1) (Q8K4D3)
Organism: Mus musculus (Mouse)
Function: Electrogenic proton/amino acid symporter with selectivity for small apolar L-amino acids, their D-enantiomers and selected amino acid derivatives such as 4-aminobutanoate/GABA. May be involved in the efflux from the lysosomal compartment of neutral amino acids resulting from proteolysis (By similarity). May play a role in specifying sites for exocytosis in neurons (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:11959859}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:Q7Z2H8}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000250|UniProtKB:Q924A5}; Multi-pass membrane protein {ECO:0000255}. Note=In neurons, colocalizes with the exocyst complex in the axonal processes. {ECO:0000250|UniProtKB:Q924A5}.
Interaction partners:
- Ras-related GTP-binding protein C
Sequence:
MSTQRLRNEDYHDYSSTDVSPEESPSEGLGSFSPGSYQRLGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFLDYGDTVMYGLECSPSTWVRNHSHWGRRIVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNVTVIPTPTMDSRLYMLSFLPFLVLLSFIRNLRVLSIFSLLANISMFVSLIMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFPLILYLGMAIITVLYISLGSLGYLQFGANIKGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIVSRVPEHFELMVDLCVRTAMVCVTCVLAILIPRLDLVISLVGSVSSSALALIIPPLLEVVTYYGEGISPLTVTKDALISILGFVGFVVGTYESLCELIQPSHSDSSTNSTSAFI
Protein: Sporulation-specific protein 22 (P25380)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Redundant with SPS2 for the organization of the beta-glucan layer of the spore wall.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
- Uncharacterized protein YCL049C
- Sporulation-specific protein 2
Sequence:
MNRITRKSCLFAIIFASLFVTHALGAAIDPPRRPHNVKPFHNGNLELQRRANEPFFEIDVKSLNTNSPISELCKKDLHVIESSHDLFHLQNQCEFILGSLKVTNYDSNILDLNSLRAIGGDLIIQDSPELIRIQAGNLNKIEGLFQLQGLTSLVSVEIPTLKFCQSLEWKVVPILNYVSMDSQNIEIIKDIVISDTSLANIENFNKVQEIDTFNINNNRFLETIHSNVKTIRGQFSVHANAKELELEMPHLREVENITIRDTSLVYLPQLTKVKSSLEFIENYFYELNLNNLQKIGGTLGIINNVNLIKVNLENLTDIQGGLMIADNESLEDITFLPNLKQIGGAIFFEGSFKDIMFDSLKLVKGSAFIKSSSNVLDCNKWTNPSNGRSIIRGGKFTCISGKKENTLNVKQDGTIIEKGYKDLTQEGEDSKKRVISKYANSANPSMQLDPLLFGTCLVAMLLF
Protein: tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase (EC 2.5.1.114) (PhTYW2) (tRNA wyosine derivatives biosynthesis protein Taw2) (O58523)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01922}.
Interaction partners:
- tRNA
- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
- Nucleoside-triphosphatase THEP1
Sequence:
MRTQGIKPRIREILSKELPEELVKLLPKRWVRIGDVLLLPLRPELEPYKHRIAEVYAEVLGVKTVLRKGHIHGETRKPDYELLYGSDTVTVHVENGIKYKLDVAKIMFSPANVKERVRMAKVAKPDELVVDMFAGIGHLSLPIAVYGKAKVIAIEKDPYTFKFLVENIHLNKVEDRMSAYNMDNRDFPGENIADRILMGYVVRTHEFIPKALSIAKDGAIIHYHNTVPEKLMPREPFETFKRITKEYGYDVEKLNELKIKRYAPGVWHVVLDLRVFKS
Protein: Auxin-responsive protein (A8MR39)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004549}.
Interaction partners:
Sequence:
MEGGSASGSASALSNDENLVVSCEDSSSPIGNELELGLTLSLGRKGYRDCRVYADDSSSSSSSSSLSRASVIAGIKRTADSMAATSGQVVGWPPIRTYRMNSMVNQAKASATEDPNLEISQAVNKNRSDSTKMRNSMFVKVTMDGIPIGRKIDLNAHKCYESLSNTLEEMFLKPKLGSRTLETDGHMETPVKILPDGSSGLVLTYEDKEGDWMLVGDVPWGMFIGSVRRLRIMKTSEATGKDDIMKQIIIYEEPFMFEAVIRQITDQREDKNIVRSFFFFSPLYSFFFGSAIFLLVSYMFSL
Protein: RNA polymerase-associated protein CTR9 (Q57V64)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cell division control protein 73 C-terminal domain-containing protein
- Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein
- FACT complex subunit
- Transcription initiation protein, putative
- Uncharacterized protein
- Spt4/RpoE2 zinc finger domain-containing protein
- Plastid-encoded RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- RNA polymerase-like protein
Sequence:
MQYISEPVQRLLDDSFEAFTKGSVDDAVAMLDAARREEKGTAELHDVFVVSCMRASIAAMCGERSLEGYMADASASPLSRPVLLYLEGVAAMTSGTSLQTASMKFEEALRVDKHFILARMGLAAVCFYMKDYKRSFSHYRAVLETVGSSAPGIVRVGLGLCAYRLGRMDAAVKWLERALAVNGEDVAALLSLLVVYLAQRRIKEVIDVVRRLQKVFPDNAMILLKTTDILYFRAVSQGRVKALAPSILHLLSEARPTARVEDAAIADYQEGRLLLALGDFTRARVLLESSMQVLPNCLAARVHYARLLFLLGRDVEAEQLLLRINAEHPNQKEVLQMLAAHASHLGLHERALECSKLLTESVAPGDVLSWTLAAWCSRLNSEESAKLLTHVLHIYEELGTPVPMKLRANKASMCGDIGTLQNILESELGEDFLSKPELPVNYVPIVYNMARLLETSDKVRACELYSYLVKHHPCFSYPYFRLYELAKAERCWRKAIMWMNLLRQAIPDEPRALVYICLLFFEQRRYAAAMNILRLAKTRSCVVALALGQIYLRHAQQHSGDSYRFLELAKDRFHFALQKDKGNVLAAHGMACCLGLEGRHESCLLLLDRVGEIVPNCSYVRKHYEAHMANAKILSDSFKQAIDYLQRDPQRAPLQSSSLAFCLFCEGRYADAIAVQKKAVDELPSEPLLRFNLALLYCASFVASISQKQEQSVQEAKELRSFLTEGLNIAHEFIKIESESRRLSEAKKLLKQLCAYCVHHNDLSIPKVVANGHRAALEAERQDAEWCRVYNEHLEQKRMLEERRLADERQRREQEQQVAGEILEDFKELHGHRVPQVKNENEGFAESPAPWFSTSVPQDLVQGELRSMEDDDAVLFSGDNFAGGVSGAGEDKSDTANDGNI
Protein: Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.5.7) (P42620)
Organism: Escherichia coli (strain K12)
Function: Catalyzes glutathione (GSH)-dependent reduction of glutathionyl-hydroquinones (GS-HQs) to the corresponding hydroquinones. Can use a variety of GS-HQs as substrates, such as GS-p-hydroquinone (GS-HQ), GS-hydroxy-p-hydroquinone (GS-HHQ), GS-methyl-p-hydroquinone (GS-MHQ), GS-menadiol, and GS-trichloro-p-hydroquinone (GS-TriCH). Also displays GSH-dependent disulfide-bond reduction activity toward HED (2-hydroxyethyl disulfide), and is able to catalyze DMA (dimethylarsinate) reduction. Exhibits no GSH transferase activity with 1-chloro-2,4-dinitrobenzene (CDNB).
Interaction partners:
- Disulfide-bond oxidoreductase YghU
Sequence:
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
Protein: Poly polymerase (Q9C9J8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At1g25400
- Nematode resistance protein-like HSPRO2
- Uncharacterized protein At5g17350
- O-fucosyltransferase 20
- DUF4228 domain protein
- F3H9.15 protein
- F21O3.6 protein)
- At2g01340
- At3g61920
- At5g37840
Sequence:
MGLCVSVNRNEYVSSSTTAKIVTINGDLREYDVPVLASQVLESESTSSSSSSSSSSYFLCNSDSLYYDDFIPAIESDEILQANQIYFVLPISKRQYRLSASDMAALAVKASVAIEKAAGKKNRRRRSGRISPVVTLNQANDNRIAAVNNRIGGEATNMMMQKGKLPNRTTPFKDTNGYSRSGSVRKLKRYTSGRAKLAVRSFRLRLSTIYEGSSFN
Protein: Serine/threonine-protein kinase nak1 (EC 2.7.11.1) (N-rich kinase 1) (O75011)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in the regulation of cell polarity, growth and division.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12427731}.
Interaction partners:
- Mo25-like protein
- Leucine-rich repeat-containing protein sog2
- Cell polarity protein mor2
- Maintenance of ploidy protein mob2
- Serine/threonine-protein kinase orb6
- Protein sts5
Sequence:
MENNTASSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMSISELTNVVKRYDTWQAAGGIPQTLLLGEEADDGSDPDQETSDTAASDDGWEFGTIKQGQSNVSSITGTSTSTTTAATSSTTVTGTVIPKSSTVHEPPSSNDSHPLLQLFKDSKISDDDSPSNAEGASTEDSKGEVSYSQIELPSLDSSNLSSKKSTIQSKHTKQAEDYDLFVGRTRSNSKTSSDQSIKRPLPRVVQRQKTSLGKRGISMSPMKPGLRMPSSFDLQSRSISMGAFEQLSTPLEAPAHKHSAVLQPLEVNRSISIPPPKSISPSILHKPSLESASSTPKISSCSSTPKPFNSKLRAHLPPLSIGSPAVQPLANDNYDSLGVRGLNMELFNDYPGNMHNIKSVLSLEIDIVLGEMDACLKSLECNLLNRKAYNE
Protein: Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20) (Peroxiredoxin-like 2B) (D3ZVR7)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9DB60}.
Interaction partners:
- Prostaglandin E synthase
- Prostaglandin G/H synthase 2
- Carbonyl reductase 1])
- Carbonyl reductase
- Thromboxane-A synthase
- Hematopoietic prostaglandin D synthase
- Prostaglandin E synthase 2
- Prostaglandin G/H synthase 1
- Prostaglandin-H2 D-isomerase
- Prostacyclin synthase
Sequence:
MSTLDLGRVGACVLKHAVTGEAVELRSLWQEKACVVAGLRRFGCMVCRWIAQDLSNLRGILDQNDVRLVGIGPEALGLQEFLDGGYFSGELYLDESKQIYKELGFKRYNSLSILPAALGKPVRDVASKAKAVGIQGNLSGDLLQSGGLLVVSKGGDRVLLHFIQSSPGDYVPQENILQALGISAEVCSSKPPQCDEEVCGR
Protein: (R)-mandelonitrile lyase 2 (EC 4.1.2.10) (Hydroxynitrile lyase 2) ((R)-oxynitrilase 2) (PaHNL1) (R-oxynitrile lyase isoenzyme 2) (Q945K2)
Organism: Prunus dulcis (Almond) (Amygdalus dulcis)
Function: Involved in cyanogenesis, the release of HCN from injured tissues. Catalyzes the stereospecific addition of HCN to a variety of aldehydes in vitro. Has no oxidase activity. The redox properties of the FAD cofactor appear to be unimportant for catalysis.
Interaction partners:
Sequence:
MEKSTMSAILLVLYIFVLHLQYSEVHSLATTSDHDFSYLSFAYDATDLELEGSYDYVIVGGGTSGCPLAATLSEKYKVLVLERGSLPTAYPNVLTADGFVYNLQQEDDGKTPVERFVSEDGIDNVRGRVLGGTSIINAGVYARANTSIYSASGVDWDMDLVNQTYEWVEDTIVYKPNSQSWQSVTKTAFLEAGVHPNHGFSLDHEEGTRITGSTFDNKGTRHAADELLNKGNSNNLRVGVHASVEKIIFSNAPGLTATGVIYRDSNGTPHQAFVRSKGEVIVSAGTIGTPQLLLLSGVGPESYLSSLNIPVVLSHPYVGQFLHDNPRNFINILPPNPIEPTIVTVLGISNDFYQCSFSSLPFTTPPFGFFPSASYPLPNSTFAHFASKVAGPLSYGSLTLKSSSNVRVSPNVKFNYYSNLTDLSHCVSGMKKIGELLSTDALKPYKVEDLPGVEGFNILGIPLPKDQTDDAAFETFCRESVASYWHYHGGCLVGKVLDGDFRVTGINALRVVDGSTFPYTPASHPQGFYLMLGRYVGIKILQERSASDLKILDSLKSAASLVL
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (A0A0B4K6L1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRRYWVSLLRHFSLIPNKSVPKVFTNGDFIQQVISFKYEQRKLSTAIYSVIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKPLQTHMFFRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWNSFYAPNKL
Protein: Non-SMC condensin I complex, subunit G (E9PWG6)
Organism: Mus musculus (Mouse)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
- Condensin complex subunit 1
- Structural maintenance of chromosomes protein 2
- Condensin complex subunit 2
- Structural maintenance of chromosomes protein 4
- Condensin-2 complex subunit D3
- Condensin-2 complex subunit G2
- Condensin-2 complex subunit H2
- Abnormal spindle-like microcephaly-associated protein homolog
- Mitotic checkpoint serine/threonine-protein kinase BUB1
- Kinesin-like protein KIF11
Sequence:
MAAQKKRLSVKEAFQLAQQPHQNQAKLVVALSRTYGAMDDKTAFQEEFIHYLKYAMVVYKREPAVERVMDFTAKFVTSFHQSDEEEEEEENDGGILNYLFTFLLQSHEANSSAVRFRVCQLTNKLLGNMPENAQIDDDLFDKINEAMLIRLKDKIPNVRIQAVLALSRLQDPKDDDCPVVDAYVNVIENDSNPEVRRAVLSCIAPSAKTLSKIVGRTKDIKDTVRKLAYQVLAEKVHMRAMSIAQRVLLLQQGLNDRSDAVKQAVQKHLLQGWLRFTEGNILEFLHRLDVENSSDVAVSVLHSLFSMTPLSELVGICKNDDGRKLIPVETLTPEIALYWCTLCEYLRSKGDEGEEFLEQILPEPAVYAEYLLSYIQGFPVVNEEQKGDFTFIGDLMKREFIGQQLILIMKSLDTSEEGGRKRLLAILQETLILPTTPISLVSLIVERLLHIIRDDNERIQIVTEIISEIRAPIVNVVVDPSDTRKKELKMAEIKVKLIEAKEALENCIAVQDFDQASKLKEEIKILEDAKINLLKETEQLEIKEVHTEKNDAETLQKCLVLCYELLKQMSTSTGITATMNGIIESLILPGIISVHPIVRNLAVLCLGCCGLQNRDFASKHFMLFLQVLQIDDVTIKISALKAIIDQLMMFGIEPFKTQKVKGVQCEGEEINCHDKQEENDAGETDPAKSVLKLLSDFLDSEVSELRTGAAEGLAKLMFSGLLVSSRILSRLILLWYNPVTEEDVRLRHCLGVFFPMFAYANRTNQECFEEAFIPTVQTLANAPVSSPLAEVDVTNVVELLVDLTRPSRLNPKAKNSQDYQALTVHDNLAIKICNEILTSPCSPENRVYTKALSLVELSSNVTKDLLLLLDEILEHVTDRTCLRALEKIKSQLGKGGKESDPGVVTQDVNTTTAVLQNENEYMTPVRDGKGTQTSKSTQGKSKRGCRKAPVSSKTNRRRQIAGPDSESDHEPPSEMKMRLPRRAKTAALQKSKLNLAEFLNEDTS
Protein: RNA helicase (EC 3.6.4.13) (F4JEL4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAGSAPEGTQFDARQFDQKLNEVLEGQDEFFTSYDDVHESFDAMGLQENLLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQLDFSLIQCQALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQAGVHVVVGTPGRVFDMLKRQSLRADNIKMFVLDEADEMLSRGFKDQIYDIFQLLPPKIQVGVFSATMPPEALEITRKFMSKPVRILVKRDELTLEGIKQFYVNVEKEEWKLETLCDLYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRSGRFGRKGVAINFVTRDDERMLCLRTWPICCEGRKEVGSVAVFALPY
Protein: Oil body-associated protein 1A (Q9ZVY7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Lipid droplet {ECO:0000269|PubMed:24406791}.
Interaction partners:
- Beta-glucosidase 22
- Oil body-associated protein 2C
Sequence:
MEKAVHLSTKNGPKVPGEPTKTGTSMVDTAASAVQSFAPINQIHQHLCAFHFYAYDMTRQVEAHHFCGHINEDMRQCLIYDGPDANARLIGLEYIVTEKLFMTLPDDEKKLWHTHEWEVKGGFLFMPGVPEAIQRQDLEKVAKTYGKVYHFWQVDLGHQLPIGLPNIMMAVTRDGQLYPEMIKETEKQFGVSIDKERESRAYMKGPDHGIHPLANGGGKGLKLELREVDIKPVESVPRVFV
Protein: Protein YIF1 (Q8IMR3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU368073}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU368073}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU368073}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU368073}.
Interaction partners:
Sequence:
MNYNPNPASAAGRPRPPKRVSDVNAMGPSAPMMGGGATFMAPPTGPGILDPNMYGAPAPAPVNSYGFDPNLGQPSQHIQQPPQQQPGYGYGAPPPQQAAGPPTYGIGAPQPVAPPTGQYPQFAMFQQPIVQDMAMQYGQKLADQGKQIMENQFEKWVPVAKLKYYFAVDNAYVGRKLRLLFFPYMHKDWSLRYDQEHPVQPRYDVNAPDLYLPTMGYITYVIVAGLLLGMQKRFSPEQLGIQASSAMAYSIFELVIYSLALYVMNVKTSLKTLDLLAFTGYKYVNIVVCLMVSTLFFKSGYYIALAYTSFSFGFFMLRTLRTKLLQDNSPAAPSGAINYDPYGNPQQFDYSGGKKRKLYFLFMIVAGQALFAFLLSKHLYLPEAEVLTVPKTF