wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein (Q389M2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPVASVSNKGAKRQRDGDGGGIVERAASHSPYSAAIEITNGTTRKAVADYLECSGLVSSISDVDVLLSSPAFRHVARSFLVPPVSAVFDGPMELGVIRLVANNDTTLLFTSDSIDPVNVPSEVGQSFCMGDVVILQRARPSCKPGDEGHESKHLLEFLTFDPSSLADAGDWCHAASWNAVTTAKWVREILSHPPGLAQVTCIVQPLVGLGADCTSSSRRVNSTGWSRSLQLPLLLRQLKRVTGVSARTVLQLKKVIFSVVRLYVAILSNAETVAPLPHILGEAIRQFVASPLFVDGLTLVLSEMAGSVSQSSWVAAQQSVLDAIWLGLRYTCGERAPTNCGGKTDCDSLQQKLHTEAERGVHAVLHRLTSIWIDSRGVDGGKADSNQPVAQLVEELARAGLFRHFVHWVRHKEQMVESSNIVGNAHCPPTMQEIRELRGLQRGTVREMMAAMASAYTPYLRQEAPRFVESSILAAYAELYGPAARAVNHFVSEPPLSEGTGDRMERWWPHISVTRVNQAAVRSSLTSYSLDEIQLHALFGMPLTATLRAAKEKKDFTRLGERGSTFGYLIVRLNGNVFVFPVIVCNVSDCSSKNCTDGEVGWTICTVDAYVLRDGDMLPSLLGASAAASVSSDTGEKFPEAWFVYEDAHGDGEKLGDAQRPQLGQEPPQFFPKGTSAISYILYIRHLQSLRRRLQHEGRKDVYAPGRLKSLQEKGSASQGRILWWGNNANDSISGNVAGTNLPASFGSSESVEDMFVTSTLLPSDGEHLRRCLDDLTEATALTPSQVECIHTLTASGRGVRTLVGAVGSGKTVIMHAASLARGRVHEELRKEHAPLWHSLIKQSGHAVSGYVAKLAMVEDMDDLFYEADTSSGRDLLEELTSEAILNINEHVQLSEKLKCCHAPLLLRPRALKHDPPKYTDRVLHEANVKDKFHSLSDALQQSYDRSMRAPLTGVLNVWLRSLRRLGNLISVVQESLDAAGEGEWKLFTEFLSWIMTQKERNDTFTEAKLRGESWMTFLGTDLWESATVVDAAAFLSADGGSGARDAPEWRSMKPLMGGTFKPVTLPNAARGLCDYGKSEAAGWLAVYGEKQTEFLNFLQKRIMNEVQYIFSFFLDLVHMVAATSQVSKVTVLTATRVSLLREILFIRMWQPRYLVIDDYDQVEDALYLALSPASVVVLSRQMDAPLQSEQQIALAVLKATQKELQGTSFFSTAVLGEALRFSAPELHKGLLLCRNSPLVNYAASRGEAPVVGSSTAEASGDHGFSGEGTHQPVQIPGFSSSSCVELWTHAVPINVGVTCDGLGAAFARARIKQVTPSYEVIVYCSSSVDRDVIIEGMSLCAEGDQADLTKVVYTLPLLPDAFVEHDEECDVAVLCLSGLARSIGHVSGLQRQKRWEQTVAEKTFVGCVERWLWKAASRARRGVLLIGSKELFRFLDPLQRIEGFAQQQRDRGEYWLPTEAKWAALALRCPEHASSRQLAILTYADYCGCKVRVIGVRECRSFCLAPYTNCTSTAHACLHACHVPSGFSQSCTCGVKGDSNLLHDRCPFPCARDQRCGHACLRSCYEPCSPCEFVGLKRLLCGQSVVTGVNDNGPTMTVVYHFQRVRCGEEPKPCEEKVTVRCPQCKTRLTMRCSDLVARGGFENFSIGELECEGCVALYNRVAKEFGLREIEAMQKRTAGEVNADLSLPVQQLPAEAQERLQKLFMIAVKKGQLMLQKEALETMQGGEASEFHRQQQIFNAQLSQQEAELRSHRDRAQENIQLWEKKLKQKYEAQLATNEEIETEVPSMLSEAIAEEERQQQYNFV
Protein: NAC domain containing protein 103 (Similarity to NAM) (Q9FMJ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- bZIP transcription factor 28
- bZIP transcription factor 60
- FAM63A-like protein
- Serine/threonine-protein kinase/endoribonuclease IRE1b
- bZIP transcription factor 17
- Heat shock 70 kDa protein BIP3
- BAG family molecular chaperone regulator 7
- Endoplasmic reticulum oxidoreductin-1
- Putative F-box protein At5g15660
Sequence:
MGKTNLAPGFRFHPTDVELVRYYLKRKVMGKKFQVDAIAEVDIYKFEPPDLPDKSCLGTGDLKWYFFCPREKKYPKGGKANRSTECGYWKTTGRDRDVSYNDEVTGKIRTLIYHYGKIPRGDRTDWVIHEYRLEDKVLAQKNVPQDTYVLCVLFKKNGLGPRHGSQYGAPFKEEDWSDKEEEYTQNHLVAGPSKETSLAAKASHSYAPKDGLTGVISESCVSDVPPLTATVLPPLTSDVIAYNPFSSSPLLEVPQVSLDGGELNSMLDLFSVDNDDCLLFDDFDYHNEVRHPDGFVNKEAPVFLGDGNFSGMFDLSNDQVVELQDLIQSPTPHPPSPPAQASIPDDSRSNGQTKDD
Protein: Protein DedA (Protein DSG-1) (P0ABP6)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- tRNA pseudouridine synthase A
- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- USG-1 protein
- Cell division protein FtsZ
Sequence:
MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK
Protein: Tensin 1 (E7ERH1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTWICLSCMLWPEDLEAPKTHRFKVKTFKKVKPCGICRQVITQEGCTCKVCSFSCHRKCQAKVAAPCVPPSNHELVPITTENAPKNVVDKGEGASRGGNTRKSLEDNGSTRVTPSVQPHLQPIRNMSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQ
Protein: Defensin (P83404)
Organism: Phlebotomus duboscqi (Sandfly)
Function: Has antiparasitic activity against promastigote forms of L.major, and antibacterial activity against Gram-positive bacterium S.aureus. Has antifungal activity against the yeasts C.albicans and S.cerevisiae, but not C.glabrata. Has antifungal activity against filamentous fungi A.fumigatus, F.culmorum, F.oxysporum, N.crassa, T.viride and T.mentagrophytes, but not B.bassiana.
Subcellular location: Secreted {ECO:0000255|PROSITE-ProRule:PRU00710, ECO:0000269|PubMed:15557638}.
Interaction partners:
Sequence:
MRTFLVTFVLVVVVGVISAYPSNPVEVEAEDFDAQDPDLQTFQDTFYEVPQVHSRQKRATCDLLSAFGVGHAACAAHCIGHGYRGGYCNSKAVCTCRR
Protein: Blistery, isoform A (Blistery, isoform C) (Blistery, isoform D) (RH56077p) (Q9VHC3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- 48 related 2, isoform D
- Serine/threonine-protein kinase par-1
Sequence:
MRTPYEESAAAADHKYQYQYTAANNNNNYYKNYNVNGNGQANGNGNLSGIGNGNGIGNGNGYGIPYHARENSLPFSYGIAKTSTPLRKTPTPTRVDSFLDFDFGPTNTNVNSNSSSNNGGTGDMIKPPTRLTSPLLVRKTLGNAVSPTSSTNTNTIANTYHYTSSSATPTPVRDNFEQLLRERREKVYNEYRNLDRESSGERARVAPAPPQRQYYPSDGYGIGLKNDSNGTLYRKSPSSNGKSTKYNYDFEFNLNLDDVRPEPTPYTTRNIHFEDLRLDQDVPDGVVNRRTMERNYHTINSLETTHKRQQLEPLEQLGAVYGQNHMEETLTRTRRDLSASTSTSKSTSPLPAIGVPAIAPASPIYATSTKRVSNPNTNGQQQMTPSPTSRPETPAFPVTPRTPFGASSSSSASLAPTTQLPPESIYQTGPRRGVPPALQPLEVSADSVQFARSSSQFWYKPNLTREDAIALLASAQPGTFLVRDSTTYKDSYGLVVRVSQPPPGSQELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVFEHSISQLALPCLLRLPDRDIVPPVRATTPAQQHLLAHGAATNVLWLYSCDTESLTGNEAIRKAIRQMYGQQPLPQPTEVHFKVSSQGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTSEGESDKKTIFAFVARRSHSSTDNQCHVFCDLSVSQPAAAIVSFANRTLPTEKLRNYVL
Protein: Glutathione S transferase E13, isoform A (EC 2.5.1.18) (Glutathione S transferase E13, isoform B) (LD22317p) (Q7JVI6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Glutathione S-transferase D4
- Glutathione S transferase T2
- Glutathione S transferase T1
- Glutathione S transferase O1
- GH16740p
- glutathione transferase
- 1-Cys peroxiredoxin
- Glutathione S-transferase D6
- Glutathione S-transferase E14
Sequence:
MSKPTLYYALFSPPARACILVAKLIGLDLELKPVDFAKKEHLSEEFVKLNPQHQIPVFVDSDGEVYVDSHAIVCFLVAKYAGNDQLYPRDLKRRAHIDHRMHYENGVLFQVVKDIVARNIYGGEGEYNPRSLTLCHNAYSDLEHFLQQGSFVVGNELSVADVSIHTTLVTLDLLIPVEREKYPQTKQWMERMDKLLPDNEEINLKGARALQTRILSCMAENKAKSQ
Protein: Penaeidin-3a (P3-a) (Pen-3a) (P81058)
Organism: Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei)
Function: Antibacterial activity against M.luteus and E.coli bacteria. Antifungal activity against N.crassa and F.oxysporum. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule {ECO:0000269|PubMed:10639333}. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Interaction partners:
Sequence:
MRLVVCLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYSG
Protein: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Complex I-AGGG) (CI-AGGG) (NADH-ubiquinone oxidoreductase AGGG subunit) (Q02374)
Organism: Bos taurus (Bovine)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:10852722, ECO:0000305|PubMed:18721790}; Peripheral membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
Interaction partners:
- Acyl carrier protein, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase 1 beta subcomplex subunit 3
- NADH-ubiquinone oxidoreductase chain 5
- NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial
- NADH dehydrogenase 1 subunit C2
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
Sequence:
MAGMSALKRLAPFAHVGGHLFRGRCARAAGARGVRRAGGGAHIEPRYRQFPQLTRSQVIQAEFFSATMWFWILWRFWHDSDAVLGHFPYPDPSQWTDEELGIPPDDED
Protein: GH24674p (Q7K3N8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDRLDYNYQEKLADLLDNEREDDEPHFLQQLRNFYTACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIWKQLMSHRKHWDPNTTNREPLTREMFDKLWASLPKIPFPFKEYYWRELSELEEKIMSYGSEDDGFDSGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFILTYIYMRLKLVAEGVSTESWHIDRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELGCLRRRFGRKRYEKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHNFAQFFCSDKELLQAHDHGSDRKRVNDAVAHFEPFREAFSCGPSPRRRQCRLY
Protein: Hippocampus abundant transcript-like protein 1 (Major facilitator superfamily domain-containing 14B) (Q5SR56)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSVEPPPELEEKAASEPEAGAMPEKRAGAQAAGSTWLQGFGRPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFAMISVSGVFSVTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDICFILVAVPESLPEKMRPVSWGAQISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYMFHVELTELGPKLNSNNVPLQGAVIPGPPFLFGACIVLMSFLVALFIPEYSKASGVQKHSNSSSGSLTNTPERGSDEDIEPLLQDSSIWELSSFEEPGNQCTEL
Protein: Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) (Q5ADM7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Phosphoglycerate kinase
- Triosephosphate isomerase
- Enolase 1
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
- Transketolase
- Glucose-6-phosphate 1-dehydrogenase
- Transaldolase
- TATA-box-binding protein
- Pyruvate kinase
Sequence:
MAIKIGINGFGRIGRLVLRVALGRKDIEVVAVNDPFIAPDYAAYMFKYDSTHGRYKGEVTASGDDLVIDGHKIKVFQERDPANIPWGKSGVDYVIESTGVFTKLEGAQKHIDAGAKKVIITAPSADAPMFVVGVNEDKYTPDLKIISNASCTTNCLAPLAKVVNDTFGIEEGLMTTVHSITATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVIPELNGKLTGMSLRVPTTDVSVVDLTVRLKKAASYEEIAQAIKKASEGPLKGVLGYTEDAVVSTDFLGSSYSSIFDEKAGILLSPTFVKLISWYDNEYGYSTRVVDLLEHVAKASA
Protein: RAD52 motif-containing protein 1 (RAD52 homolog B) (Q8NG50)
Organism: Homo sapiens (Human)
Function: May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:17905820}. Cytoplasm {ECO:0000269|PubMed:17905820}. Nucleus, nucleolus {ECO:0000269|PubMed:17905820}. Note=Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Nucleus, PML body. Nucleus, Cajal body. Note=Isoform 1 is predominantly cytoplasmic. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress.
Interaction partners:
- DNA repair protein RAD52 homolog
- D
Sequence:
MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVEEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGVRCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD
Protein: Replicative DNA helicase DnaB (EC 5.6.2.3) (DNA 5'-3' helicase DnaB) (Q9X4C9)
Organism: Geobacillus stearothermophilus (Bacillus stearothermophilus)
Interaction partners:
Sequence:
MSELFSERIPPQSIEAEQAVLGAVFLDPAALVPASEILIPEDFYRAAHQKIFHAMLRVADRGEPVDLVTVTAELAASEQLEEIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIRTATSIAQDGYTREDEIDVLLDEADRKIMEVSQRKHSGAFKNIKDILVQTYDNIEMLHNRDGEITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKTNENVAIFSLEMSAQQLVMRMLCAEGNINAQNLRTGKLTPEDWGKLTMAMGSLSNAGIYIDDTPSIRVSDIRAKCRRLKQESGLGMIVIDYLQLIQGSGRSKENRQQEVSEISRSLKALARELEVPVIALSQLSRSVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNKDSENKNIIEIIIAKQRNGPVGTVQLAFIKEYNKFVNLERRFDEAQIPPGA
Protein: Purine nucleoside permease (Q5AGW8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Nucleoside permease that transports adenosine and guanosine. Does not show any transport activities towards cytidine, adenine, guanine, uridine, and uracil.
Interaction partners:
- Cytochrome c oxidase subunit
- Importin subunit alpha
- DNA-directed RNA polymerases I and III subunit RPAC1
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
- DNA-directed RNA polymerase III subunit
- DNA-directed RNA polymerase III subunit
- Pom152p
Sequence:
MKLSTLFTLATTISTLTTFTIASPVVVVEKRAINETALAEDIPTTKNNHAQTSYGKPFAIYQPKAFIISMFSLERDPWLKAMDFVHNITIPGLSPVYPDIHCTTNYTICQITTGEGEINAASSISALTLNPLFDLTKTYFLVGGIAGGEPNYTTIGGVTFAKYAVQVGLEYQLAYEDYHKTNPDWISGYIPYGTDDQNTYPGNVYGTEVFEVNEKLRDRAVELASKVHLNNGTEGNAKFRKLYNETAAQGLPKVVKCDSLTSDNYFTGNVLNDYFANFTLLMTNGSATYCSTAQEDNATLEVMTRLAKHGLVDYDRIMIMRTISDFSRPPPSMSAYEYFFNRSDGGISASLENLVIAGTPIIHDIVQNWDKIYESGEKYSSKNYVGDIFATLGGKPDFGKESFDTA
Protein: Calcineurin binding protein 1 (B9EKC5)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MIRIAALNASSTIEDDHEGSFKSHKIQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYSHLTTCEPPRPSLGKRIDLSDYQDPSQLLASSVVVTPVSVVQPSPICTNPTVAVAEPVLSYTSVTAASFPLHSPSLLDTGTPMGDVSGGDKSKKGVKRKKTVEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQAEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGLLELMMRYLKSMGHKFLLKWPPGLADVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSSAIQAQAGAEQGDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDHRQCFECSDVALNEAVQQMLNSSESAAKEEWVATVTQLLLGIEQALSSDSSGSILKESSSTTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGIPEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVQVLQKELAVSASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEAPCLPEGADPTPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRSELPPELVQQMEDRRDSMLETARHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVSFMKEAAEGPFARGEEKNMPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQAAPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKLFPEKRLSGLSAQAGPSGKDLPGPTEERGKTEESLESTEAFRVVEQSVQKPVADSSASAYIPSKPPASTPPLWDGKKRGDSLGEPVAFPQGLPAGAEEQRQFLTEQCISSFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSEHPGSKACGLSGARMTTDVSHKASPEDGQESPQHPKKLPLADGSGPGPEPGGRMGPLNQLPVVTDIRDNTDQGGEQKDKESPQVGPTEPMDTSEAAGRHSDLEQTSRLLPGRPPRDRGPESRSAELSLEELSISTRQQPAPLAPSPAAPTTTAAPTTMAARGAGHSEEAPPRPNRKRKLLEDTESGKTLLLDAYRVWQQGQKGMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAATQRQASGDTPTTPKHPKDSRENFFPATVVPTVPDPTAPDALQRPSDSHLKPVLATVITCPPSASASIPDLSTDPGIPRPHRPETTPSRAPLSPEGEEASGVTEGTSTLPQEPRYSHQIKMAATGHLAEQHCWPVEVACQTGAEPTCSQASSTKVPSSGSTQTAESHQGKTESSRAKSRLLPNMPKLVIPSATTKSPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV
Protein: Protein BASIC PENTACYSTEINE2 (AtBPC2) (GAGA-binding transcriptional activator BBR/BPC2) (Q9LDE2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Galactan beta-1,4-galactosyltransferase GALS1
Sequence:
MDDDGFRNWGYYEPAAATFKGNLGLQLMSTIDRNTKPFLPGRDPNLMMGPNGSYHHQEPPIHMSYNWINQQKDKFFNMLPVTTATPNYGNVLPETSSAPSMQMNLHHHLQTEENPVKLEEEIVVQTKKRKTNAKAGSTPKAKKPRKPKDENSNNNNNNNTNVTRVKPAKKSVDLVINGVSMDISGLPVPICTCTGAPQQCYRWGCGGWQSACCTTNISMHPLPMSTKRRGARISGRKMSQGAFKKVLEKLASDGFNFGNPIDLKSHWARHGTNKFVTIR
Protein: Ribitol-5-phosphate xylosyltransferase 1 (EC 2.4.2.61) (Transmembrane protein 5) (UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase) (Q9Y2B1)
Organism: Homo sapiens (Human)
Function: Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan (Probable). Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (Probable).
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:25279699, ECO:0000269|PubMed:29477842}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Ribitol 5-phosphate transferase FKRP
- Beta-1,4-glucuronyltransferase 1
- Ribitol-5-phosphate transferase FKTN
- Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1
- Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
- UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
- Protein O-mannose kinase
- Protein O-mannosyl-transferase 2
- Protein O-mannosyl-transferase 1
- Mannose-1-phosphate guanylyltransferase catalytic subunit beta
Sequence:
MRLTRKRLCSFLIALYCLFSLYAAYHVFFGRRRQAPAGSPRGLRKGAAPARERRGREQSTLESEEWNPWEGDEKNEQQHRFKTSLQILDKSTKGKTDLSVQIWGKAAIGLYLWEHIFEGLLDPSDVTAQWREGKSIVGRTQYSFITGPAVIPGYFSVDVNNVVLILNGREKAKIFYATQWLLYAQNLVQIQKLQHLAVVLLGNEHCDNEWINPFLKRNGGFVELLFIIYDSPWINDVDVFQWPLGVATYRNFPVVEASWSMLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS
Protein: Actin-binding vascular maintenance protein (Smoothelin, like) (Q76C07)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDAGPLASVAEGSPEGETVCAALARYETTLRDAVREIHVDVSAFKLGIERRLEEAIHVSGPLGRAVAQLQQENRQLRGQLEALTRQVEMLTGSVCDRSALLTGGSQSSNSTGHQSPPSAAPSVAALTGSASGSASSPTTTRFSSRATFSVTSKTNSIERDEPIEVDPAPIPQGLENGHLSSTENSIVPLRRNSPPNGVLHEHSAPVPMAMPHLPITATTKVADSTVMKSPESPSSPMQATPSAITDSLTSSPPVTSDNQPQLESPVHAVSSVKTWAPTPARTMGSPRLTEKASSAPAKSVTYSGLFPHNTDRNVDTPGDLSFGRGIERRRELVRSQTLPRNIGAQARRSIFERLDSENNSRPKPVDSKPKLKRSQSFGVSSASSIKQILLEWCRSKTIGYQNIDIQNFSSSWSDGMAFCALVHSFFPTEFDYNGLTPAERKHNFELAFSTAEKKAGCDRLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRKFE
Protein: DASH complex subunit DAM1 (DUO1 and MPS1-interacting protein 1) (Kinetochore assembly protein DAM1) (Outer kinetochore protein DAM1) (P53267)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B. Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
Subcellular location: Nucleus {ECO:0000269|PubMed:11698664, ECO:0000269|PubMed:21256019, ECO:0000269|PubMed:9817759}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17620411, ECO:0000269|PubMed:9817759}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:11698664, ECO:0000269|PubMed:21256019}. Note=Associates with the mitotic spindle and the kinetochore (PubMed:21256019, PubMed:9817759). Localizes to microtubule plus-ends (PubMed:17620411). {ECO:0000269|PubMed:17620411, ECO:0000269|PubMed:21256019, ECO:0000269|PubMed:9817759}.
Interaction partners:
- DASH complex subunit ASK1
- DASH complex subunit DUO1
- DASH complex subunit SPC34
- DASH complex subunit DAD1
- DASH complex subunit SPC19
- DASH complex subunit DAD2
- DASH complex subunit DAD3
- DASH complex subunit DAD4
- DASH complex subunit HSK3
- Inner kinetochore subunit IML3
Sequence:
MSEDKAKLGTTRSATEYRLSIGSAPTSRRSSMGESSSLMKFADQEGLTSSVGEYNENTIQQLLLPKIRELSDSIITLDSNFTRLNFIHESLADLNESLGSLLYGIMSNSWCVEFSQAPHDIQDDLIAIKQLKSLEDEKNNLVMELSNMERGIKRKKDEQGENDLAKASQNKQFNQPLFPSSQVRKYRSYDNRDKRKPSKIGNNLQVENEEDYEDDTSSEASFVLNPTNIGMSKSSQGHVTKTTRLNNNTNSKLRRKSILHTIRNSIASGADLPIENDNVVNLGDLHPNNRISLGSGAARVVNGPVTKNRNSMFSGRAERKPTESRHSVAKKTEKKINTRPPFR
Protein: Cytochrome P450 26B1 (Cyp26B1) (EC 1.14.13.-) (Retinoic acid-metabolizing cytochrome) (Q6EIG3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Appears to be involved in the inactivation of all-trans-retinoic acid (RA). Plays a role in skeletal development.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O43174}; Peripheral membrane protein {ECO:0000250|UniProtKB:O43174}. Microsome membrane {ECO:0000250|UniProtKB:O43174}; Peripheral membrane protein {ECO:0000250|UniProtKB:O43174}.
Interaction partners:
- Aldehyde dehydrogenase 1 family member A3
- Aldehyde dehydrogenase 1 family, member A2
- Cytochrome P450 1A
- Cytochrome P450, family 3, subfamily A, polypeptide 65
- Cytochrome P450 26C1
- Aldehyde oxidase 6
- Xanthine dehydrogenase/oxidase
- Cytochrome P450 26A1
- Retinol dehydrogenase 10-B
- Arginyl-tRNA synthetase
Sequence:
MLFESFDLVSALATLAACLVSMALLLAVPQQLWQLRWTATRDKSCKLPMPKGSMGFPIIGETCHWFFQGAGFHASRRQKYGNVFKTHLLGRPLIRVTGAENVRKVLMGEHSLVTVDWPQSTSTLLGPNSLANSIGDIHRKRRKIFAKVFSHEALESYLPKIQQVIQETLRVWSSNPDPINVYRESQRLSFNMAVRVLLGFRIPEEEMHCLFSTFQEFVENVFSLPIDLPFSGYRKGIRARDSLQKSIEKAIREKPLHTQGKDYTDALDVLLESAKENNTELTMQELKESTIELIFAAFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHDGCLCQGELRLDSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFELDGVQVPKGWSVMYSIRDTHDTSAVFKDVEAFDPDRFSPERSEDREGRFHYLPFGGGVRSCLGKQLATLFLKLLAVELAGGSRFELSTRTFPRMISVPVVHPTDGLRVKFFGLDSNQNQIMAKSDEMLDATV
Protein: Conserved protein (O53953)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible exported protein
- Secreted protein
Sequence:
MRVVSTLLSIPLMIGLAVPAHAGPSGDDAVFLASLERAGITYSHPDQAIASGKAVCALVESGESGLQVVNELRTRNPGFSMDGCCKFAAISAHVYCPHQITKTSVSAK