wanglab/gogpt-training-data huggingface dataset:
Protein: FI07234p (Mitochondrial ribosomal protein S28) (A1ZBA5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small ribosomal subunit protein mS26
- Small ribosomal subunit protein bS16m
- GH07821p
- Small ribosomal subunit protein mS40
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS7m
- GEO10172p1
- Mitochondrial ribosomal protein S21, isoform A
- Mitochondrial ribosomal protein S23
- Small ribosomal subunit protein uS3m
Sequence:
MSLLQKLSRSGVPMASLTCRSRMPMVIRLISGNTEKPAEESTPAVNTETAEIGSSKGGFARAFDKYTAPATPPQLPEDNQTFASLLRNSKLIDLDNAEGKVVSGKIFHVVGDDLYIDFGWKFHCVCSRPTRNASDYVRGARVRLRIKDLELSTKFLGSSKDITILEADCHLLGLLSTPTRQSTAKTTPKIEDIL
Protein: Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] (Q9WV92)
Organism: Mus musculus (Mouse)
Function: Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5 (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:10652311}; Peripheral membrane protein {ECO:0000269|PubMed:10652311}; Cytoplasmic side {ECO:0000269|PubMed:10652311}. Cytoplasm {ECO:0000250}. Cell junction {ECO:0000269|PubMed:10652311}. Note=Detected in the cytoplasm of actively dividing cells.
Interaction partners:
- Cell adhesion molecule 1
- Spectrin beta chain, non-erythrocytic 1
- Spectrin alpha chain, non-erythrocytic 1
- Protein arginine N-methyltransferase 3
Sequence:
MTTESGSDSESKPDQEAEPQEAAGPQGQAGAQPGPEPAGGNGSLNGEKQQPALEQFPEAAAHSTPVKREIGDKDRDFAAAAAKQLEYQQFEDDKLSQRSSSSKLSRSPLKIVKRPKSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQIRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGNDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVSENHEIYMKDSVSAAEVGTGQYATTKGISQTNLITTVTPEKKAEEERVEEEDRRKKAEEATPVTALRHEGKTDSERTDTAADGETSATESDQEEDAEIKAQDLDKTQDELMKHQTNISELKRTFLETSTETALTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEILSLLESARKPTEFIGGVSSTTQSWVQKLETKTEPVEAEVESTPHPQPLSTEKVLQETILVEERHVMSVHASGDASHTARDEVDAAESTPTDRRHTGKGKEGSSVTEAAKEQRGEEVDQSAPEQEQPATVSHEEEQASTIRTSEGLEQKSHFESSTVRVESTSVGSISPGGAKLEISTKEVPVVHTETKTITYESSQVDPGADLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED
Protein: F-box protein DOR (Protein DROUGHT TOLERANCE REPRESSOR) (Q5BPS3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Negative regulator of guard cell abscisic acid (ABA) signaling, especially during drought stress.
Interaction partners:
- SKP1-like protein 14
- F-box protein At3g17320
- F-box/kelch-repeat protein At2g22030
- Cullin-1
- Putative F-box/kelch-repeat protein At1g60570
- Putative F-box only protein 10
- F-box/kelch-repeat protein At2g43270
- F-box protein At3g08750
- FBD-associated F-box protein At4g10400
- F-box protein At2g07140
Sequence:
MKSRRQNVSVARQTILGRDENFEPIPIDLVIEIFSRSPVKSIARCRCVSKLWASILRLPYFTELYLTKSCARPRLLFACQKHRELFFFSTPQPHNPNESSSPLAASFHMKIPFDGRFNIISPIGGLVFVRYEQILKGRKTPEFVSAICNPSTGQSLTLPKPKTRKRIWGTSHFGYDPIEKQFKVLSMNIGDGVYKEHYVLTLGTENLSWRRIECSIPHVHGSKGICINGVLYYRAKADMFSGTLMIVCFDVRFEKFSYIKILKPTTTLISYNGKLASLVWEGPSYICGKRFEMWVLGDPEKHEWLKHTYELRPRWQNVLGEDLLIFAGMTGTNEIVLSPKYPSHPFYVFYYNLERNTIRRVEIQGMGAFKVNEDYIFLDHVEDVKLI
Protein: BSLF2/BMLF1 (ICP27-like protein) (K9USF9)
Organism: Epstein-Barr virus (strain GD1) (HHV-4) (Human gammaherpesvirus 4)
Interaction partners:
Sequence:
MVPSQRLSRTSSISSNEDPAESHILELEAVSDTNTDCDMDPMEGSEEHSTDGEISSSEEEDEDPTPAHAIPARPSSVVITPTSASFVIPRKKWDLQDKTVTLHRSPLCRDEDEKEETGNSSYTRGHKRRRGEVHGCTDESYGKRRHLPPGARAPRAPRAPRVPRAPRSPRAPRSNRATRGPRSESRGAGRSTRKQARQERSQRPLPNKPWFDMSLVKPVSKITFVTLPSPLASLTLEPIQDPFLQSMLAVAAHPEIGAWQKVQPRHELRRSYKTLREFFTKSTNKDTWLDARMQAIQNAGLCTLVAMLEETIFWLQEITYHGDLPLAPAEDILLACAMSLSKVILTKLKELAPCFLPNTRDYNFVKQLFYITCATARQNKVVETLSSSYVKQPLCLLAAYAAVAPAYINANCRRRHDEVEFLGHYIKNYNPGTLSSLLTEAVETHTRDCRSASCSRLVRAILSPGTGSLGLFFVPGLNQ
Protein: Actin-histidine N-methyltransferase (EC 2.1.1.85) (Protein-L-histidine N-tele-methyltransferase) (SET domain-containing protein 3) (hSETD3) (Q86TU7)
Organism: Homo sapiens (Human)
Function: Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:28442573, ECO:0000269|PubMed:30626964}. Nucleus {ECO:0000269|PubMed:28442573}. Note=Localizes mainly in the cytoplasm. {ECO:0000269|PubMed:28442573}.
Interaction partners:
- Actin, cytoplasmic 1
- Actin, cytoplasmic 2
- Actin, alpha skeletal muscle
- Actin, gamma-enteric smooth muscle
- Actin, aortic smooth muscle
- Actin, alpha cardiac muscle 1
- Histone-lysine N-methyltransferase NSD3
- Histone-lysine N-methyltransferase SMYD3
- N-lysine methyltransferase SMYD2
- Histone-lysine N-methyltransferase SETMAR
Sequence:
MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKATENGLVNGENSIPNGTRSENESLNQESKRAVEDAKGSSSDSTAGVKE
Protein: DnaJ heat shock protein family (Hsp40) member B12 (V9GY70)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHRRVTDHLGVVYYVGDTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCSRLSETMKSLENFW
Protein: poly(A)-specific ribonuclease (EC 3.1.13.4) (A8E5K6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- CCR4-NOT transcription complex subunit 2
- CCR4-NOT transcription complex subunit 1
- CCR4-NOT transcription complex subunit 9
- CCR4-NOT transcription complex subunit 6-like
- poly
- CCR4-NOT transcription complex subunit 3
- CCR4-NOT transcription complex subunit 11
- CCR4-NOT transcription complex subunit 10
- CCR4-NOT transcription complex subunit 3
- m7GpppN-mRNA hydrolase
Sequence:
MPAALADTSQIICEVWASNVEEEMRKIRQIIQNYNYIAMDTEFPGVVVRPIGEFRSTVDYQYQLLRCNVDLLKIIQLGLTFMNEDGDYPPGTTTWQFNFKFNLTEDMYSQDSIDLLQNSGLQFKKHEEEGIDTLYFAELLMTSGLVLCENVKWLSFHSGYDFGYLVKLLTDSRLPEEEHEFFQILNLFFPAIYDVKYLMKSCKNLKGGLQEVADQLELKRIGRQHQAGSDSLLTGMAFFRMKELFFEDNIDDAKYCGRLYGLGSGSTQSQNGISNSSQEETNNKH
Protein: Myb-binding protein 1A (Q9W5E4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Has a role in rRNA biogenesis, cell proliferation and tissue growth by contributing to the localization of nclb to the nucleolus.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9BQG0}. Nucleus {ECO:0000305|PubMed:29065309}. Nucleus, nucleolus {ECO:0000305|PubMed:29065309}.
Interaction partners:
- Trifunctional purine biosynthetic protein adenosine-3
- KRR1 small subunit processome component homolog
- HEAT repeat-containing protein 1 homolog
- Nucleolar protein 6
- LD41718p
- LD10780p
- FI03455p
- Ribosome biogenesis protein BOP1 homolog
- rRNA biogenesis protein RRP5
- Lethal
Sequence:
MKSKVDKPVTNGAPNATKTKAKEDRKRAKTQKSEADSQIPAKILKKSKKEKPAETEEKENTASNANLKVSQINKAVFVVFKKMQGSQLTKKMINSLITLLRDDTNAEQRTATTGYVLKRLIRSTGADDMKTVSLAASYIHCILNAVPAIDAFEVLETLKRDLAVGSQQRGKEDSLAAVGQLVTAFCILQTPQFAKAEPKLVTAVFQILAAQLKGREYLVSLCGDILAVSFKQLPAAIFEEYVWPLLQPELNKPLSGLKVNTCDVLLAVHLTFSSVLGRENILASLWPKKPVYTQLFDLYFSGSTIHSDGVYARLASFLVNGGKDMLAAWQQYIDSKQPLKLNAAKACAIQVLSHVLLNFKPREEQLILDIFTPTCVQFLLHECSSVKWDKGEGKKPSLKKLKEICFKFEGSLVLCYEKQFQNDDNKLHLLLKLLEHTLQLDSVISLPRFCQKLINQLSVESLHKLYDYYNNKLYSLEDEDRVSRVHCLNQMQLILNHSKLSQTAKWRQKQLNYLLLAGLFHLDASKKPCEAAQASAFSRQCAARCEEIFLGSLLHKCSGLPGLCQLLQKTLSYLNKELGQPDAESKLRSPRDESLQKAWKQVEKLLERPSKESDVVGQSFEALILFVSLALCTKIPPSITVLEDLIICRKNALQKSKEQVNEELKWQDVLTDALLQLLLQTGHFWREFVQLVATALIPHLEHGNLEQVLEVLNMNKNPLSKKSDGEEESDDELDKEESLKDSSDDSEDEDEDEEEDEGEDDAESHLAQIRESVRQALVNDGDADDDGASSVDWNDVDEEQGERLNAALERSFQMFRPKSRKAQEKERPTKSERIDSTNLLHFRIRALDLLELFITKKPTQSVILDVLHCVFQVYSHCAADSKLQSLREASLKLLKKILARNIELKENQSTAPILEAIEQLMSSGEEHSEEDQENGKQPASRQAKRDIIIWRDRCFAYLVSQASADGEPKKSAVWPLLVEFLELWVAKRRSRLSLASFEALFQSGQWQGVAPLAVVLASHLDVQKTRSFRRAQILKLLSEQGRRLEVAFKDNNSSSKKFEKQIARYVNQLETKASSSKELNLLLKILAQGGEKWQKLREQIQLVAKDLQPNKKVAKQKKQAAAKPMVVEDEEST
Protein: DnaJ (Hsp40) homolog, subfamily A, member 3 variant (DnaJ (Hsp40) homolog, subfamily A, member 3, isoform CRA_b) (Q53G26)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAARCSTRWLLVVVGTPRLPAISGRGARPPREGVVGAWLSRKLSVPAFASSLTSCGPRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGSAGFDPGASGSQHSYWKGGPTVDPEELFRKIFGEFSSSSFGDFQTVFDQPQEYFMELTFNQAAKGVNKEFTVNIMDTCERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIIISPCVVCRGAGQAKQKKRVMIPVPAGVEDGQTVRMPVGKREIFITFRVQKSPVFRRDGADIHSDLFISIAQALLGGTARAQGLYETINVTIPPGTQTDQKIRMGGKGIPRINSYGYGDHYIHIKIRVPKRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSGGSTMDSSAGSKARREAGEDEEGFLSKLKKMFTS
Protein: Nuclear receptor co-repressor 2 (A0A8I6AN60)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSGSTQPVAQTWRAAEPRYPPHGISYPVQIARPHTDVGLLEYQHHPRDYTSHLSPGSIIQPQRRRPSLLSEFQPGSERSQELHLRPESRTFLPELGKPDIEFTESKRPRLELLPDTLLRPAPLLATGQPSGSEDLTKDRSLAGKLEPVSPPSPPHADPELELTPSRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRVWPAGTNHLEPRVPATVEPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQRFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMDDPMKVYKDRQVTNMWSEQERDTFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQQMARSSQEEKEEKEKEKEADKEEEKQDAENEKEELSKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANHEETATPQQSSELASMEMNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKTPAAASEETAFPPAAEDEEMEASGASANEEELAEEAEAYSRLSSCLHVAAVNNSSDTESVPSPRTEATKDAGPKPASTEALPAATQPPVPPPEEPATVPDEPCPAPDASGPPSPVASPPPAAPPAAVDKDEQDQAATVPQTEDAKEQKSEAEELVIDVGKTEEPEAPEEPPESVKSDHKEETEEEPEDKAKGPEAIETVSEAPLKVEEAGSKAAVTKGSSSGATQDSDSSATCSADEVDEPEGGDKGRLLSPRPSLLTPAGDPRASTSPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDTVPPKPAPPVPPPTQHLQPEGDVSQQSGGSPRGKCRSPVPPAEKEAEKASFFPAFPAEGPKLPTEPPRWTSGLPFPIPPREVIKTSPHAADPSAFSYTPPGHPLPLGLHDSARPVLPRPPISNPPPLISSAKHPGVLERQLGTISQGMSVQLRVPHSEHAKAPMGPLTMGLPLAVDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQETSVLRGTALGSTASGSITKGLPSTRTADGPSYRGSITHVGAGGRVGWAGILGGLGWDERTSGETRDLELNGWSLRCGVRPRVMKKTGGMSVSQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRTITSASIEGLMGRAIPEQHSPHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPPRDLTETYKTRPLDPLGPLKLKPTHEGVVATVKEAGRSIHEIPREELRRTPELPLAPRPLKEGSITQGTPLKYDSGVPSSGSKKHDVRSIIGSPGRPFPALHPLDIMADARALERACYEESLKSRSGTSSGAGGSITRGAPVVVPELGKPRQSPLAYEDHGAPFTSHLPRGSPVTTREPTPRLQEGSLLSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVTGVDLYRGHIPLAFDPTSIPRGIPLEAAAAAYYLPRHLAPSPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAASAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAIDRLAYLPTAPPPFSSRHSSSPLSPGGPTHLAKPTATSSSERERERERERDKSILTSTTTVEHAPIWRPGTEQSSGAGGSSRPASHTHQHSPISPRTQDALQQRPSVLHNTSMKGVVTSVEPGTPTVLRWARSTSTSSPVRPAATFPPATHCPLGGTLEGVYPTLMEPVLLPKETSRVTRPERPRVDAGHAFLTKPPAREPASSPSKSSEPRSLAPPSSSHTAIARTPAKSLAPHHASPDLPAPTSASDLHREKTQSKPFSIQELELRSLGYHSGAGYSPDGVEPISPVSSPSLTHDKGLSKPLEELEKSHLEGELRHKQPGPMKLSGEAAHLPHLRPLPESQPSSSPLLQTAPGIKGHQRVVTLAQHISEVITQDYTRHHPQQLSGPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGTPARGSPHSEGGKRSPEPSKTVLSSSEDAIEPVSPPEGMTEPGHARSTAYPLLYRDGEQGEPRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNIGQPGTEIFNMPAITGAGLMTCRSQAVQEHASTNMGLEAIIRKALMGGGGKAKVSGRPSSRKAKSPAPGLAPGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLAAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
Protein: Dehydrin family protein (Q9T022)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At4g38410
- Dehydrin Xero 1
- Dehydrin HIRD11
- RING-H2 finger protein ATL18
- Dehydrin Rab18
- Dehydrin ERD14
- 1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal
- Dehydrin Xero 2
- Dehydrin ERD10
- Esterase/lipase/thioesterase family protein
Sequence:
MADLKDERGNPIYLTDAHGEPAQLMDEFGNAMHLTGVATTVPHLKESSYTGPHPITAPVTTTNTPHHAQPISVSHDPLQDHDLRWFGTSSTEENGEGVGRKTNITDETKSKLGVDKPSAATVTGSGSGSVHEKKGFFKKIKEKLSGHHNDL
Protein: C2H2-type domain-containing protein (Q3UZI7)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFGSTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGAKAFPGMLPMGMYGAHIPTMPSAGMPHSLVHNTLPMGMSYPLESSPISSSAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSAGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ
Protein: Translocating chain-associated membrane protein 2 (Q15035)
Organism: Homo sapiens (Human)
Function: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Denticleless protein homolog
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
- Sarcolipin
- Phospholamban
- Fibrocystin
Sequence:
MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
Protein: Polyamine aminopropyltransferase 1 (Caldopentamine synthase) (Norspermidine aminopropyltransferase) (EC 2.5.1.126) (Norspermine aminopropyltransferase) (EC 2.5.1.127) (Norspermine synthase) (Spermidine aminopropyltransferase) (EC 2.5.1.79) (Thermospermine synthase) (Triamine/tetramine aminopropyltransferase) (A2BIX4)
Organism: Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)
Function: Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high-temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to norspermidine, spermidine and norspermine to yield norspermine, thermospermine and caldopentamine, respectively. It can also synthesize sym-norspermidine (bis(3-aminopropyl)amine) from 1,3-diaminopropane with a very low activity. The biosynthesis of caldohexamine and caldoheptamine from caldopentamine has been also observed.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00198}.
Interaction partners:
- Arginine decarboxylase proenzyme
- S-adenosylmethionine decarboxylase proenzyme
- Agmatinase
- S-methyl-5'-thioadenosine phosphorylase
- Polyamine aminopropyltransferase 2
- Cytosine deaminase
- S-methyl-5-thioadenosine phosphorylase
Sequence:
MELGMFRLNIYQPGGPIGALYPVEKILYHGRSQYQEIMILVLRGFGKTLVLDGLIQSTESDEHIYHETLVHPAMTVHPNPRRVLILGGGEGATLREVLKHNTVEKAVMVDIDGEVVRVAREYLPEWHQGAFDDPRAQVVIMDGFEYIKEAARRGEDFDVIIMDLTDPFGPKIAAKLYTKEAIGLVKSVLRSDGILVTQAGCAALFPEAFEKVYGSVKSLFAHAEEYGVWVPSFMYVNSFVFASDKYRLTDLSMEEVDRRLRERGVETRFYSGLRHYTLIGLGGIRLLEGRGS
Protein: Small ribosomal subunit protein eS25x (40S ribosomal protein S25-3) (Q8GYL5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein uS10y
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein eS28x
- Small ribosomal subunit protein eS28z/eS28y
- Small ribosomal subunit protein eS1z
- Small ribosomal subunit protein eS21y
- Small ribosomal subunit protein eS24y
- Small ribosomal subunit protein eS1y
- Small ribosomal subunit protein eS12y
Sequence:
MAPKKDKVPPPSSKPAKSGGGKQKKKKWSKGKQKEKVNNMVLFDQATYDKLLSEAPKFKLITPSILSDRLRINGSLARRAIRELMAKGTIRMVSAHSSQQIYTRATHG
Protein: Beta-heavy-spectrin (Q23980)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
TQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPENVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSKIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRITMLEQLFRHQLEQEKISKLQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAASQEKTPIFSSPMVTPAQTSGPQSPALSQVQLRPPFGDDNEHLALQKSSSSGMFGDRLRRGSADANVKRAESMKVQPKQAKRTPSFTTRRRAQSFRKNQKGEGFDLPPVEIQGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQKTATAPVNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKISFHASLPPNMQLLSYDESMKQQSSSSPDIKVTSSVESPVSSRNSSPDSQRRTSGAQVLDGTATPQMAFLQRQMQQQQQQQQSQPSSPTGGFDQKPPIPPRGAAPVASHRQSQENLVVMRNRQSSNDLQQSATLPAGLTGVQQNGNGKDDNALLTRNSEARQSGWGNTRFESNRPVSLQPDSISFSRVSAESSSESEAQSISSVSGVKGSKGTKEERRSGMFRIFGRKGDKEKEKDKDKRRSSQVPPQ
Protein: UPF0643 protein PB2B2.08 (Q9HDU7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized protein PB2B2.11
- Probable 2-dehydropantoate 2-reductase
- Uncharacterized oxidoreductase C663.06c
- UPF0591 membrane protein C15E1.02c
- UPF0300 protein C737.04
Sequence:
MIVQHKTAKIEEDHGLFQPILRPSDISKTTDTKFIQSSPYIEKEHWLDLGTLSVGHYFLSLALQTFVPKDSVRYAHLPYAQAFDIAEIVNLIREYSHKYHKHIPAFSAYIVAFRSVLQPEVQVSPEARHKLAEIDKGSHLEANVSGGLLKYWYGIPDDVFGQNLATCWWTSKESARLGGAGKIHREGLKAVRGWYKNWKIEEYELEVIEGGSSYIFKGLS
Protein: Serine/threonine-protein kinase-like protein CCR4 (EC 2.7.11.1) (CRINKLY 4-related kinase 1) (AtCRK1) (Protein CRINKLY 4 RELATED 4) (AtCCR4) (Q9FIJ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Gamma-aminobutyrate transaminase POP2, mitochondrial
- Pumilio homolog 5
- Protein GL2-INTERACTING REPRESSOR 1
- Probable CCR4-associated factor 1 homolog 9
Sequence:
MALTISISCFSSYFVSLLLLVLSSFSFVCFSLSTVSISHISNQTLVCALNNHSYLQCSSFPLNSIPFSLTGNLRNRRFSGVVSGNGFVCGLISRLDSNTSTLLCWRFSVDGTNMLHKRIYHGPELEELEAGNFRICGVERVSRRLRCWQPYYLPRPDNYRSIALGDNFFCGLSQPPGMISCEGIAKVPSGDHYIAIAAGSRQACAITVDNDVECWGQTQSLPREKFLALAVGEDRGCGVRWSNGTVVCWGNNNNFSLPQTLKDIHFTSIYAKGPMFCGVATRNYTLICWGNENFKSGVFTPFQGLISQVVMPGPCRRECPYRPLSGSQSLCGNELMICDLKRNDGEFPDTRAQNSKNKTWSRRNIAFLVVGCVGTFSLLLVISFLIFKSHCRCRVHDSGRLDDTRTIDIPKLEKRLCTLASLGNPGQLMEFSIDELALATDGFSVRFHLGIGSFGSVYQGVLSDGRHVAIKRAELTNPTLSGTTMRHRRADKDSAFVNELESMSRLNHKNLVRLLGFYEDTEERILVYEYMKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPVIHRDIKSSNILLDATWTAKVSDFGLSQMGPTEEDDVSHLSLHAAGTLGYIDPEYYKFQQLTTKSDVYSFGVVLLELLSGHKAIHNNEDENPRNLVEYVVPYILLDEAHRILDQRIPPPTPYEIEAVAHVGYLAAECLMPCSRKRPSMVEVVSKLESALAACLTAPKTETVSRSNTY
Protein: NAC domain-containing protein 26 (ONAC026) (OsNAC26) (Q5VNK1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor that acts redundantly with NAC20 to regulate the expression of genes involved in the biosynthesis of starch and storage proteins in grain. Directly binds to the promoters of starch synthase 1 (SS1), pullulanase (PUL), glutelin A1 (GLUA1), glutelins B4 and B5 (GLUB4 and GLUB5), alpha-globulin and 16 kDa prolamin, and activates their expression.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353, ECO:0000269|PubMed:27872632, ECO:0000269|PubMed:32989010}.
Interaction partners:
Sequence:
MGEQQQQVERQPDLPPGFRFHPTDEEIITFYLAPKVVDSRGFCVAAIGEVDLNKCEPWDLPGKAKMNGEKEWYFYCQKDRKYPTGMRTNRATEAGYWKATGKDKEIFRNHHMLIGMKKTLVFYKGRAPKGDKTNWVMHEYRLADASPPQPPPPPSSAEPPRQDDWAVCRIFHKSSGIKKPVQVPMQMPMQMQMPVAHQVPAANYQQQMAMASASIIQVPMQMQMPSMSDQLQMLDDFSTGSLMAPPPPPPSYSTLPGFPLQINGGAQQFVGNPSMYYQQQQQQQQQQMDMAAGGFVVSEPSSLVVSPQDAADQNNAADISSVACNMDATIWKY
Protein: Potassium channel toxin alpha-KTx 8.5 (OdK1) (Potassium channel toxin KTx7) (ODKTx7) (P0CC12)
Organism: Odontobuthus doriae (Yellow Iranian scorpion)
Function: Selectively inhibits voltage-gated potassium channels Kv1.2/KCNA2 (IC(50)=183 nM).
Subcellular location: Secreted {ECO:0000269|PubMed:17070524}.
Interaction partners:
Sequence:
MSRLYAIILIALVLNVIMTIMPDSKVEAVSCEDCPEHCSTQKARAKCDNDKCVCESV
Protein: FI01416p (Q0E8X8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- ATP synthase subunit gamma, mitochondrial
- ATP synthase subunit alpha, mitochondrial
- ATP synthase F
- ATP synthase subunit O, mitochondrial
- ATP synthase subunit beta
- ATP synthase subunit beta, mitochondrial
- ATP synthase subunit g
Sequence:
MFVVRRSASRLYPAGVQLAKMSGSQVGDLGSGAGKGGGGGGSIREAGGAFGKLEAAREEEYFYKKQREQLDRLKNDQIHQAEFHHQQIKEHEEAIQRHKEFLENLHK
Protein: Chromosome 6 open reading frame 142 isoform 2 (A0A0S2Z6I7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MCSWYLGFECSVSAGGSEAKPLIFTFVPTVRRLPTHTQLADTSKFLVKIPEESSDKSPETVNRSKSNDYLTLNAGSQQERDQAKLTCPSEVSGTILQEREFEANKLQGMQQSDLFKAEYVLIVDSEGEDEAASRKVEQGPPGGIGTAAVRPKSLAISSSLVSDVVRPKTQGTDLKTSSHPEMLHGMAPQQKHGQQYKTKSSYKAFAAIPTNTLLLEQKALDEPAKTESVSKDNTLEPPVETPTTLPRAAGRETKYANLSSPSSTVSESQLTKPGVIRPVPVKSRILLKKEEEVYEPNPFSKYLEDNSDLFSEQDVTVPPKPVSLHPLYQTKLYPPAKSLLHPQTLSHADCLAPGPFSHLSFSLSDEQENSHTLLSHNACNKLSHPMVAIPEHEALDSKEQ