wanglab/gogpt-training-data huggingface dataset:
Protein: Kelch repeat-containing protein 1 (P38853)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a role in cell morphogenesis and cell fusion and may antagonize the PKC1 pathway.
Interaction partners:
- Kelch repeat-containing protein 2
- Bud site selection protein 14
- Guanine nucleotide exchange factor LTE1
- Protein SPA2
- Cell division control protein 42
- Uncharacterized protein YMR124W
- Protein TEM1
- Serine/threonine protein kinase KIN1
- Protein BNI1
- Nuclear fusion protein FUS2
Sequence:
MAGFSFAKKFTHKKHGKTPSDASISDQSREASLSTPPNEKFFTKQETPQKGRQFSQGYHSNVNKTSSPPMFARKQVSESRIQPSAVPPQQRNVSGPSTTLHKQLSKQREYTVWNRIKLQNSPFPRYRHVASAYVTDKNQIYVIGGLHDQSVYGDTWILTAFDNATRFSTTTIDISEATPPPRVGHAAVLCGNAFVVFGGDTHKVNKEGLMDDDIYLLNINSYKWTVPAPVGPRPLGRYGHKISIIATTQMKTKLYVFGGQFDDTYFNDLAVYDLSSFRRPDSHWEFLKPRTFTPPPITNFTMISYDSKLWVFGGDTLQGLVNDVFMYDPAINDWFIIDTTGEKPPPVQEHATVVYNDLMCVVGGKDEHDAYLNSVYFLNLKSRKWFKLPVFTAGIPQGRSGHSLTLLKNDKILIMGGDKFDYARVEEYDLHTSDIDMQRGTIVYTLDLARIKDLCPGVMDVPTDTPTPRNGNLDLATPVTPTSHQTKNMNVPISAAPLASAPSPAPKDFSDADRLNREVHNRNVSTEHQNQSHPVNSESHLIAEPNILTPYVPSESSQTPVMKITSNKPFDTPTIQKEPDLSETMDPTVGNQRIPSSIYGDNLTPANQIKNNSPILETLPSNEIKTPQNGNIEEIKHLPDADEKIDSTTTFDQEINGDKLGTSSMSKVEEDGNVADEDDEIGVAQMASSPSKDQFKIKHYNESSELSQNNTEIDKLSEPVDITIKKSDTAGHDSANHVIDASDEKNVSPMGDVPTDTKNEEASVPINRDATTEVVDRALFEKLRSELQSLKELTHEKALEAGAHIKELETELWQLKSQKNSGTTKEIDELDSVRLQSKCEILEADNHSLEDKVNELEELVNSKFLDIENLNEVIQFQNEKIKSLELEPNYKEKLEELQIEHENLSRENERLKNESKQHNEDIINNVANYSSQLGSLISHWKENRANSSFLESSSSLISVSDENGEKTVGEPYGDQSRHHRVVINKLTNRLDDLLERSQELTISKEKLSSEYHALKMEHSSLSQDVLVKENEIKKIQNDYKESISSMDSASKALMVSQRELEKYKSLNKKLIDELDELKFKNGVCSENFENGLRSTEESSNNVKNSNSIRENQFNIKINDLKAELFITNQERDDLKSEVLELKKRLLNLENNTKQVNEDADSDLL
Protein: ComM protein (Q9ABT0)
Organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus)
Interaction partners:
- DprA protein
- Competence protein F
- ComEC/Rec2 family protein
- Peptide deformylase
Sequence:
MAARVVTVAFEGVEARRVDVEVQLTTGQHAFVVVGLADKAVAESRERVRGAFAGLGLSLPGKRIVANLAPADLPKEGAHFDLPIALAVMAALGVIPLDALDGWAAMGELSLDGRIVPAAGALPAAMAAGAMDLGLICPEASGPEAAWAGGTRILAPRSLVALINHFRGSQILSAPTPGPIIEGEVPKDLRDVKGQEHAKRALEIAAAGGHNLLFCGPPGSGKSMLAQRLPSLLPPLTSAELLETSMVHSVAGLIARGTLTRARPFRAPHHSASMAALTGGGHRAKPGEVSLAHNGVLFLDELPEFGVQALDSLRGPLETGEVMVARANAHVRYPAKVQLVAAMNPCRCGHGGAGRGACGKAPRCQKDYQGRISGPLLDRIDLAVDMPAVTAADLALPPPVEGSAEVAARVARARALQVDRAEALGAADGLNSRAEGAFLEKIAGLDTAGRDLLSRAAEAGRISARGWTRVLRLSRTIADLEGVDSVKRLHVAEALAYRRTSAAGDEDVGSPPRRIENTSRAFSDEVDPVRRQKMR
Protein: 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B) (P28222)
Organism: Homo sapiens (Human)
Function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1315531, ECO:0000269|PubMed:1328844, ECO:0000269|PubMed:1348246, ECO:0000269|PubMed:1351684, ECO:0000269|PubMed:1559993, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1610347, ECO:0000269|PubMed:23519210, ECO:0000269|PubMed:23519215}; Multi-pass membrane protein {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1315531, ECO:0000269|PubMed:1328844, ECO:0000269|PubMed:1348246, ECO:0000269|PubMed:1351684, ECO:0000269|PubMed:1559993, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1610347, ECO:0000269|PubMed:23519210, ECO:0000269|PubMed:23519215}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- 5-hydroxytryptamine receptor 1D
- Sodium-dependent serotonin transporter
- 5-hydroxytryptamine receptor 1A
- Tryptophan 5-hydroxylase 1
- Guanine nucleotide-binding protein G
- Protein S100-A10
- 5-hydroxytryptamine receptor 2A
- Tryptophan 5-hydroxylase 2
Sequence:
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
Protein: Glycerophosphodiester phosphodiesterase domain-containing protein 5 (Glycerophosphocholine phosphodiesterase GDPD5) (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 2) (Phosphoinositide phospholipase C GDPD5) (EC 3.1.4.11) (Q640M6)
Organism: Mus musculus (Mouse)
Function: Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation. Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (By similarity). May contribute to the osmotic regulation of cellular glycerophosphocholine.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:17275818, ECO:0000269|PubMed:18667693, ECO:0000305|PubMed:15276213}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:15276213, ECO:0000269|PubMed:17275818, ECO:0000269|PubMed:18667693}. Cell projection, growth cone {ECO:0000269|PubMed:17275818}.
Interaction partners:
Sequence:
MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLVCTFSLTLTWLYFWWGVHNDYDEFNWYLYNRMGYWSDWSVPILVTSAAAFTYIAGLLVLALCHIAVGQQLNLHWIHKMGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHIGALVAITALSWIVAGQFARAERSSSQLTILCTFFAVVFTFYLIPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTVMSFRKALEQRLYGLQADITISLDGVPFLMHDTTLRRTTNVEHLFPELARRPAAMLNWTVLQRLNAGQWFLKTDPFWTASSLSPSDHREVQNQSICSLAELLELAKGNASLLLNLRDPPRDHPYRGSFLNVTLEAVLRSGFPQHQVMWLFNRQRPLVRKMAPGFQQTSGSKEAIANLRKGHIQKLNLRYTQVSHQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHTLSRVPSPLWIMPPDEYCLMWVTADLISFSLIIGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDELSVCSDSSYDTYANANSTATPVGPRNAGSRAKTVTEQSGH
Protein: At4g08940 (Ubiquitin carboxyl-terminal hydrolase family protein) (Q6NQB8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transmembrane 9 superfamily member 11
Sequence:
MAWLRFFSRTLKSLPQISSSSPNPNPNFRTSPFSTSFLITKTPDKLKKKRKKPESARTKSIQHESTKLPHLESLVSRDAHFRFLIRSKEFISKQPERILRLDDAGKLYRELGFPRGRKVTKFIPKHPLIFQTYRHSDGKIWLGFTEFMEDLLDEEKGLMESMELDRVNCVRKLLMMTKDKRILLSKIHHTRLLFGIPEDFRDRVAKYPDYFRVVTGGDGNRVLELVNWDTNLAVSELERLFMIDEDKAKRVFKFPVKHGKELELEEKDTRKLNLLNTFPLVSPYSDGWKLDVWSLEAEKYRVGIVHEFLNLTLEKRASIHHIVEFKDEFSLTRQTYQMLKKQSMSFYLAGTEMNWTVFLKDAYDENGVLVSKDPQVVFNEKLYKYADMQQMEQVG
Protein: E3 ubiquitin-protein ligase RNF25 (EC 2.3.2.27) (RING finger protein 25) (RING finger protein AO7) (Q9QZR0)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2. Stimulates transcription mediated by NF-kappa-B (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q7SXJ6}.
Interaction partners:
Sequence:
MAASASTAAGEEDWVLPSEVEVLESIYLDELQVMKGNGRSPWEIFITLHPATAEVQDSQFVCFTLVLRIPVQYPHEVPQISIRNPRGLSDEQIHKISQALGHVAKEGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELTTQEQEQERQHVVTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEELKLLYQRQQEKGGIIDLEAERNRYFISLQQPPAALEPESAVDVSREPQPPNALSAEQSTSLADQSTLPTSLPMTTQYTYEKTSGAGPNQQRPGETQKSVLDPPRHGRGSWRQYDRRHPKGGECCTPKGTSEIHELPPPEKPLKETVDLKAEPRNKGLTGHPQEKGPGSWQGPSARRTRDCARWERSKNRTPGSCYPHLPRGQGAYRSGTRREPLGLESEEGS
Protein: CCAAT/enhancer-binding protein gamma (C/EBP gamma) (P53567)
Organism: Homo sapiens (Human)
Function: Transcription factor that binds to the promoter and the enhancer regions of target genes. Binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis-acting element in the G-CSF gene promoter.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P53568}.
Interaction partners:
- Cyclic AMP-dependent transcription factor ATF-4
- CCAAT/enhancer-binding protein beta
- Cyclic AMP-dependent transcription factor ATF-5
- DNA damage-inducible transcript 3 protein
- MHC class II transactivator
- Cyclic AMP-dependent transcription factor ATF-3
- Transcription factor Jun
- Tribbles homolog 3
- Jun dimerization protein 2
- Protein c-Fos
Sequence:
MSKISQQNSTPGVNGISVIHTQAHASGLQQVPQLVPAGPGGGGKAVAPSKQSKKSSPMDRNSDEYRQRRERNNMAVKKSRLKSKQKAQDTLQRVNQLKEENERLEAKIKLLTKELSVLKDLFLEHAHNLADNVQSISTENTTADGDNAGQ
Protein: Polycystin-2-like protein 1 (Polycystin-2L1) (Polycystic kidney disease 2-like 1 protein) (Polycystin-2 homolog) (Polycystin-L) (Polycystin-L1) (Q9P0L9)
Organism: Homo sapiens (Human)
Function: Pore-forming subunit of a heterotetrameric, non-selective cation channel that is permeable to Ca(2+). Pore-forming subunit of a calcium-permeant ion channel formed by PKD1L2 and PKD1L1 in primary cilia, where it controls cilium calcium concentration, but does not affect cytoplasmic calcium concentration. The channel formed by PKD1L2 and PKD1L1 in primary cilia regulates sonic hedgehog/SHH signaling and GLI2 transcription. Pore-forming subunit of a channel formed by PKD1L2 and PKD1L3 that contributes to sour taste perception in gustatory cells. The heteromeric channel formed by PKD1L2 and PKD1L3 is activated by low pH, but opens only when the extracellular pH rises again. May play a role in the perception of carbonation taste (By similarity). May play a role in the sensory perception of water, via a mechanism that activates the channel in response to dilution of salivary bicarbonate and changes in salivary pH (By similarity).
Subcellular location: Cell projection, cilium membrane {ECO:0000269|PubMed:24336289}; Multi-pass membrane protein {ECO:0000269|PubMed:30004384}. Cell membrane {ECO:0000269|PubMed:10517637, ECO:0000269|PubMed:11959145, ECO:0000269|PubMed:23212381, ECO:0000269|PubMed:25820328, ECO:0000269|PubMed:27754867, ECO:0000269|PubMed:29425510}; Multi-pass membrane protein {ECO:0000269|PubMed:30004384}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:A2A259}. Note=Interaction with PKD1L3 is required for localization to the cell membrane (PubMed:23212381). Interaction with PKD1 is required for localization to the cell membrane (By similarity). {ECO:0000250|UniProtKB:A2A259, ECO:0000269|PubMed:23212381}.
Interaction partners:
- Polycystin-1-like protein 3
- Polycystin-1-like protein 1
- Transient receptor potential cation channel subfamily M member 5
- Short transient receptor potential channel 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
- Carbonic anhydrase 4
- Taste receptor type 1 member 1
- Proton channel OTOP1
- Polycystin-1
Sequence:
MNAVGSPEGQELQKLGSGAWDNPAYSGPPSPHGTLRVCTISSTGPLQPQPKKPEDEPQETAYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLERKGWLAPSPGVKEQAIWKHPQPAPAVTPDPWGVQGGQESEVPYKREEEALEERRLSRGEIPTLQRS
Protein: Putative outer membrane protein YiaT (P37681)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell outer membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized HTH-type transcriptional regulator YbhD
- Uncharacterized HTH-type transcriptional regulator YiaU
- Uncharacterized HTH-type transcriptional regulator YgfI
- Inner membrane protein YlaC
Sequence:
MLINRNIVALFALPFMASATASELSIGAGAAYNESPYRGYNENTKAIPLISYEGDTFYVRQTTLGFILSQSEKNELSLTASWMPLEFDPTDNDDYAMQQLDKRDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGVLYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYSELPEEITDSPMIDRNESFTFVTGVSWRF
Protein: Carnitine O-palmitoyltransferase 1, liver isoform isoform X1 (Carnitine palmitoyltransferase 1Ab (liver)) (E9QI17)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAEAHQAVAFQFTVTPDGIDLHLCHEALRQIYLSGIHSWKKRFIRFKNGVMTGVYPGSPSGLVVVLVGYMSSTKYAKIDPSLGILTKLSTHLPVSKYITEDGQRIVGGVLVGTGLWIAVTFVMRNALKYLLSWHGWMFNQHGTLSLKTKIWLVLVKLFSGPKPMLYSFQSSLPRLPVPPVKDTVRRYLESARPLMDDEQYKRMEGLAKDFEKNLGPKLQWYLKLKSWWTSNYVSDWWEEYIYLRGRSPIMVNSNYYAMDFLYVNPTSLQAARAGNSIHAMMMYRRKLDRAQIKPLYLLENRVPLCSAQWERMFNTCRIPGLETDVLQHVNESKHIAVYHKGRFYKVWMFYDGRLLLPREIEQQMERILADKSEPQPGEEFLAALTAGDRVPWAKARSQFFIRGKNKQSLDAVEKAAFFVTLDDSEQRYEPDNPIQSLDSYGKSLLHGKCYDRWFDKSLNLIVFKNGTMGLNAEHSWADAPIVGHLWEQVLSSDPVRLGYTEEGHCKGNPHPNMPGPQRLQWDIPEECQTVISSSLKVANTLADDVDMHIFPFNDFGKGLIKKCKTSPDGFIQLALQLAHFRDKGKFCLTYEASMTRLFREGRTETVRSCTNETCAFVHAMMDEKATREERLKLLKAATEKHQNLYKLAMTGKGIDRHLFCLYLVSKYLGEDSPFLKEVLSEPWRLSTSQTPLQQMELFDLKKHPEYVTSGGGFGPVADDGYGVSYIILGEDLINFHISSKHSSHETDSHRFGSNIKQAMLDILDLFQLDIKPNKK
Protein: glutathione transferase (EC 2.5.1.18) (Q9ZP60)
Organism: Zea mays (Maize)
Interaction partners:
- glutathione transferase
- Dehydroascorbate reductase like3
- Dehydroascorbate reductase like1
- F-box protein FBL2
- Dehydroascorbate reductase
- Glutathione S-transferase DHAR3 chloroplastic
- Gluconokinase
- AP2-EREBP transcription factor
- glutathione transferase
- Glutathione S-transferase 4
Sequence:
MSPPVKILGHYASPYSHRVEAALRLKGVPYELVQEDLGNKSELLLAKNPVHKKVPVLLHGDRAVCESLLIVEYVDEAFDGPSILPADPHDRAVARFWANFLDTKFSQPFWLAYWAEGEAQKAVVKEAKENLALLEAQLGGKSFFGGDTPGYLDIAACALGPWIGVLEEVTGVALLDADEFPALCQWARDYSSSEALRPCLPDRDRLVAYFTENKEKYKTFAKATLHQ
Protein: Structural maintenance of chromosomes 6 (A0A2S1ZR87)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome, telomere {ECO:0000256|ARBA:ARBA00004574}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAKRKEENFSSPKNAKRPRQEELEDFDKDGDEDECKGTTLTAAEVGIIESIHLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVKDGQNSADISITLRNRGDDAFKASVYGNSILIQQHISIDGSRSYKLKSATGSVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQIHQGEERLTELKRQCVEKEERFQSIAGLSTMKTNLESLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLDRKMEEQQVRLNEAEQKYKDIQDKLEKISEETNARAPECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDEQLCKRIEELKKSTDQSLEPERLERQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVKHALSYNQRQLKELKDSKTDRLKRFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKRFYLPGTSRPPIIVSEFRNEIYDVRHRAAYHPDFPTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSENTRPKFLSRDVDSEISDLENEVENKTAQILNLQQHLSALEKDIKHNEELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVEKSASILDKEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDLDSKVRTLKKFIKLLGEIMEHRFKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDDQR
Protein: beta-fructofuranosidase (EC 3.2.1.26) (C4PBL7)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Vacuole lumen {ECO:0000256|ARBA:ARBA00004410}.
Interaction partners:
Sequence:
MEASSSTSHDPALFHAPLLHHPRRRSSRPLKGFAVIFGSVVFLLSLVILIVNQSPEPLASNPSSVTEAGSYSMAAQPRGIAEGVSAKSNPSLFDKVGFNWTNAMFYWQRTAYHFQPQKNWMNDPDGPLYHKGWYHLFYQYNPDSAIWGNITWGHAVSKDLIHWFYLPLAMVPDQWYDINGCWTGSATLLPDGRIVMLYTGSTNESVQVQNLAYPANLSDPLLLQWLKYPGNPVVVPPTGIEDNEFRDPTTAWLGPDGSWRITVGTRFNTTIGTALVFQTTNFSDYQLLDGVLHAVPGTGMWECVDFYPVAINGSVGLDTTALGPGIKHVLKASLDDTKVDHYAIGTYDMITDKWTPDNPEEDVGIGLKVDYGRYYASKTFFDQSKQRRILYGWVNETDTEADDLEKGWASIQTIPRSVLYDNKTGTHLLQWPVEEVESLRLNATVFKDVVVEAGSVVPLDIGTATQLDILAEFEIETLVSNSTEDEVSDCGDGAVDRNTYGPFGVLVIADDSLSELTPIYFRPLNISDGSLETYFCADETRSSKAPNVTKRVYGGKVPVLDDENYNMRVLVDHSVVESFGEGGRTVITSRVYPTEAIYGAARLFLFNNASRVNVKATLKIWEMNSAFIRPFPFEETLFQEMVAST
Protein: Protein Son (RNA-binding protein Son) (Q9VHB0)
Organism: Drosophila melanogaster (Fruit fly)
Function: RNA-binding protein that protects nascent transcripts containing intronic transposable sequences, known as INE-1, from being degraded by DIP1. Modulates DIP1 activity by repressing its sumoylation levels. This ensures that intronic sequences will be degradated only after splicing. In the ovaries, regulates germline stem cells (GSCs) self-renewal by repressing the expression of the GSC differentiation-promoting factor Rga.
Subcellular location: Nucleus {ECO:0000269|PubMed:31730657}. Note=Localizes to DIP1-positive nuclear bodies known as satellite bodies. {ECO:0000269|PubMed:31730657}.
Interaction partners:
- DISCO interacting protein 1, isoform D
- Caper, isoform A
- BcDNA.LD23634
- Histone-lysine N-methyltransferase Set2
- Splicing factor 3B subunit 1
- Serine/threonine-protein kinase PRP4 homolog
- Regulator of gene activity
Sequence:
MTENTEKGASVETPQVAGSQTNPPVQEPLALTKIPPIKVKSERPDAEVEAKLRAMNAKIKAEMVTLMRRSNSNELGNNDESGESESSASADDKKNIKPVKSSNEILAELFGVFNAAPPEELLDDNLFKKKKKVKKEKKDKKAKKKKTTKSDGECSDSEAEGKHKHKRKKHKHKDIRVKDKEKDRDRDKSKEKDRDRVTDKSKEKDRDRDRDRDKSKDKFTAAQAPSEKEKEKSESRKRSAVEPSSHSEKRERHEREKHRDWEREREREKEHERERVRSNNSFYNGQREADRLKGSESASTKSRQEQDLSDISLSDEESYLREKASNGRRRAHNSFYDEKEELSVSPKRNVRESNTRRNRKSRSRSRDLGIDKKRLLEIARRNAINMFKQGTMPGVANMTAEVKDKVLVKMRYGGRTIQDLTDFCKKISNGDGLSDLSSEEESDVDKNGNAKVFHHPFQLKEREPIVMHIRNSTALVPAPPRLDEQTKAITMQFPVSSGQTHRNNEVWVPVDPKDSLVPLPSLPPAKQATNMFKETPKNVFAKSIPLQEQQEPAFKPLGGAVVVPPLAATQLPTVPQSVPPTVPKEFAPPAVPFVPEVPIPSTSPVTPMQSASIFPDVTPPSMDVSSIITQRLSAIRRLQENPADSEALKMMYTAQRNMSSWANSKHLPGQFTGSTGAQVMKAHELNSGPQLWVRKDQMTSTKPVTGGMGMALLQKMGWKPGEGLGRCKTGSLQPLLLDVKLDKRGLVSRDDLRPPQMRAPAAQRRNKNMAGPIGAGPCPAVQGAGPGPLASTPLVTQDKHPVCVLNELTSKNKWMPPQYKLRQDIGPAHNRSFLFSVEINGQTFTPDRGSNNKKEAKLNAAALCLRSLGILPPS
Protein: Fibroblast growth factor 14 (FGF-14) (Fibroblast growth factor homologous factor 4) (FHF-4) (Q92915)
Organism: Homo sapiens (Human)
Function: Probably involved in nervous system development and function.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Sodium channel protein type 8 subunit alpha
- C-Jun-amino-terminal kinase-interacting protein 2
- Sodium channel protein type 2 subunit alpha
- Fibroblast growth factor 17
Sequence:
MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
Protein: Leucine-rich repeat protein (LRRP) (Q585L7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MIVPPPWGDDDQRKLPERRSGTFSNVFWSSLSTYIGNTVKELQELLEAGAVLNASVCAGAGNVCDDVRPVVPKRLEGVRAACPVISMEELPPIDFCEDTDAVVRAQSRCLRYTQSLMQLLDVTRGCCGSWGRLHRGERNRLRKALTEEAEARFSLVELCTYFVDLRFCHKGIDALTPDIFQFSNVTKLVLSNNPGLTSIPYLPPACLVFIACGCNIRQICGSNTLALVGLSFNAMDGLDFINEMPSLRVLDLTRNTVFDLVLAIDSLRNHPTLDDVTFTGCPIALLDNYKENITRGCPRLRKLDGVTLPCANNALSASPRKAPSVEDGASTYHSCVATPRELSFLVSTGVPIAVTVVKLEGVSNLFHTLLPRDDRSLIERPEPKARKGKRKAKPAAVGISYEFATHFSLKGSWGGEEGAILKCENIPILPAAPSGRATTASRRTLQPSPNAIDNVAELNHTARANIPTSAKLSDLLAQALAITLEVRDDVQFASGNSVTLTYEMGTFVADCSSLLLSTGPPPRALSVKVPIILSEAALAEKRVHARELRKNLTNSLQLLVSASQAPQSSSPLVAANSGSFRRRSKKSTSDRMNASDRFPTETRRLEDDLDELRLLSNIEEKRVDELSSLEMVLTLELSIGSAPKNNNSESSLINRTGRRRAGAKGAAPVA
Protein: Carboxylic ester hydrolase (EC 3.1.1.-) (Q9VP25)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RE68566p
Sequence:
MRRRGVYVMLTLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAELEDCLTLSVYTKNLSASQPVMFYIYGGGFYNGSSEDHPPNYLLEKDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQLVKCIQKAKVIDILKATASESFSPIVGDLHGILPQQPSELVKSYRRQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGLTDNILNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHPLEGQDTQMSQKMVDVWTSFAIEGVPRNLSPLSSASGPYNKLNLEVTKGDDLLDTLTAAIDDPDNGRLQREDMEF
Protein: Aquaporin TIP4-4 (Tonoplast intrinsic protein 4-4) (ZmTIP4-4) (ZmTIP4;4) (Q9ATL3)
Organism: Zea mays (Maize)
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Subcellular location: Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Tonoplast.
Interaction partners:
Sequence:
MAKFALGHHREASDAGCVRAVLAELILTFLFVFAGVGSAMATGKLAGGGGDTVVGLTAVALAHTLVVAVMVSAGLHVSGGHINPAVTLGLAATGRITLFRSALYVAAQLLGSTLACLLLAFLAVADSGVPVHALGAGVGALRGVLMEAVLTFSLLFAVYATVVDPRRAVGGMGPLLVGLVVGANVLAGGPFSGASMNPARSFGPALVAGVWADHWVYWVGPLIGGPLAGLVYDGLFMAQGGHEPLPRDDTDF
Protein: Erythrocyte membrane protein band 4.1 like 1 (A0A1B0GTW6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANESQRTQDISQRDLVPEPGAAAGLEVFTQKSLAASPEGSEHWVFIEREYTRPEELGLLKVTTMQQEERQAGLAGILANGRLSKVDVLVDKFKVEVATEEMVGNRRANTQQQGKMIASPEDFESVGEEGPWIRESPGGAALASGRTLAEKLLEGSELRADTREATIRNRCMSDGQPEGQTELRKGLEEPHTCGRPTAPGTRPAEVDVLSPASDKGGLQSFLLDPAHAEARAELSNETDTSFAERSFYLNYEEKDSEDQVLPPPLEERKGRLDAPPGGEPRPTLNSLDLRVSAAASSRSKDEAHMTSPKEGAGTPKNHGGPGDLKGSPAGQTFAEGWEDAQWGVEGEFPHLTASAAREEGTPVSGDLLGKAEESPTEELKKHPPHRGQGVHPDPQACALPRAIPLNVRKPVKPDRGNFPPKERGVVPTQKGGAELKDREASAFLHMEVIIPLPASPGHSEDLAALEEASPSPTSHGSGEPSELREPFLRHVHLSKASPEPKDQVGFVVSPATGGERRPPPITSRKPRVVPEEAEGRIPLGFGFPSGKRREMTSFQAGDQEGSLEDISKTSVANKIRIFETHGAETRRMSEGEARSLPNDVSSEAPVGQAEQQRSTLSDLGFAQLQPPGDFASPKATHSTVIPLATRHFREDTSASYQEAHTELEPVSPNSGCETTLAEATGTGNKSGDAVREEKRSTNLAANTPGKGGRLRFASPSGPQRAGLREGSEEKVKPPRPRAPESDTGDEDQDQERDTVFLKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYHGSAFEDFSRSLPELDRDKSDSDTEGLLFSRDLNKGAPSQDDESGGIEDSPDRGACSTPDMPQFEPVKTETMTVSSLAIRKKIEPEAVLQTRVSAMDNTQVDGSASVGREFIATTPSITTETISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYGATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES