wanglab/gogpt-training-data huggingface dataset:
Protein: DNA gyrase subunit B (EC 5.6.2.2) (Q59533)
Organism: Mycobacterium leprae (strain TN)
Function: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01898}.
Interaction partners:
- DNA gyrase subunit A
- DNA replication and repair protein RecF
- DNA-directed RNA polymerase subunit beta
- Beta sliding clamp
- N-acetyltransferase domain-containing protein
- DNA-directed RNA polymerase subunit beta'
- DNA-directed RNA polymerase subunit alpha
- Protein RecA
- Protein translocase subunit SecA 1
- SsrA-binding protein
Sequence:
MAAQRKAQDEYGAASITILEGLEAVRKRPGMYVGSTGERGLHHLIWEVVDNSVDEAMAGYATQVDVRLFDDGSVEVADNGRGIPVAVHATGVPTVDVVMTQLHAGGKFGGKDSGYNVSGGLHGVGVSVVNALSTRVEVDIKRDGYEWSQFYDKAVPGILKQGEATEATGTTIRFWADPDIFETTKYDFGTVARRIQEVAFLNKGLTINLVDERVKQDEVVDDVVSDTAEAPVAMTVEEKSTESSAPHKVRHRTFHYPGGLVDFVKHINRTKTPIQQSIIDFDGKGAGHEVEVAMQWNGGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQRVCNEQLIHWFEANPVDAKAVVNKAISSAQARIAARKARELVRRKSATDLGGLPGKLADCRSTDPRSSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDISRLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIEHGYVFLAQPPLYKLKWQRMDPEFAYSDSERDGLLETGLKLGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV
Protein: C-X-C motif chemokine 5 (Cytokine LIX) (Small-inducible cytokine B5) (P97885)
Organism: Rattus norvegicus (Rat)
Function: May participate in the recruitment of inflammatory cells by injured or infected tissue.
Subcellular location: Secreted.
Interaction partners:
- C-X-C chemokine receptor type 2
- C-X-C chemokine receptor type 1
- C-X-C motif chemokine 14
- C-X-C chemokine receptor type 4
- Growth-regulated alpha protein
- Eotaxin
- C-X-C chemokine receptor type 3
- Macrophage inflammatory protein-1 alpha receptor
- C-C motif chemokine 2
- C-C chemokine receptor type 3
Sequence:
MSFQLRSSARIPSRSCSSFTLLAFLLLFTLPQHRAQAAPFSAMVATELRCVCLTLAPRINPKMIANLEVIPAGPHCPKVEVIAKLKNQKDNVCLDPQAPLIKKVIQKILGSENKKTKRNALALVRSASTQ
Protein: Neuron navigator 2 (V9GX91)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MPAILVASKMKSGLPKPVHSAAPILHVPPARTGPQPCYLKLGSKVEVSKTAYTSQIPLKSQGLQEPTGEGLPLLKSSSLENGFDTQIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANDKIEDINGCPKNRSQMIENIDACLNFLAAKGINTQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQQQQPEKQPLSSSPLPPAGSQVAGAPSQCQAGTPQHQGLATPQAPCQLLQPVSHQQGKTQVEMQSRLPGPTARVAAAGSEAKTRGGSAAANNRRSQSFNNYDKSKPVTSPPPPAPPSNHEKEPLASSASSHPGMSENVPAPLENSPSVPVNCSSSAIPQPSMTSKPWRSKSLSVKHTATSAMLSVKPAGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGSASRDTSCERLEILPSFEETEELEATANRALSTVGPASSSPKIALKGIAQRTFSRALTNKKSSPKGNEKEKEKQQREKEKEKEKEKGKDLTKRVSVTDRPDLKEETKADLSGVAVTEMPKKSSKIASFIPKGGKLNSTKKEATAPSHSGIPKPGMKNVSAKSPSAPIPPKEGERSRGKLSSGLPPQKAQLDSRHSSSSSSLASSEGKGPGGTSLNPSISSQTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSAGVSMEPSHYTKSGQPALEELTEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFISAEAGRYVYSAPLRRQLASRGSSICHVDVSDKADDDVDLEGISMDAPGYMSDGDVLSKNIRSDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRRNLDVQTDAEKHSQVERNSLWSGDDIKKSDGGSDSGVKMEPGSKWRRNPSDMSDESDKSVSGKKNPVLSQTGSWRRGMTAEVGITMPRTKPSAPTGTLKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKTLPSSSRTPTVNANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRPTGRKTSMDGAPNQDDGYLSLSSRTNLQYRSLPRPSKSNSRNGAGNRCSTSSIDSNMSSKSAGLPVPKLREPSKASLGSSLPGLVNQTDKEKGISSDSESVASCNSVKVNPATQPVSSSAQATLQPGTKYADVASPTLRRLFGGKPTKPIATAETMKSAVVISNPHATLTQQGNLESPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSGPSNSLTWGTSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGGLSHNSSPGPVASTKEDSLMPFVRTSSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWFRSHSAGGLQDTATNSPFSSGSSVTSPSGTRFNFSQLASPTAVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSAQATDLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNAHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSLGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEAMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIVHVDPVSQLGLSSDSVLGYSIGEIKRSNASETPELLPCGYLVGENTTILVTVKGLTENSLDSLVFESLIPKPILQRYVSLLTEHRRIILSGPSGTGKTYLANRLSEYVVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNAELVKIINWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSLPREGSTSKQVPPSDTEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL
Protein: RH19933p (Q8IGH4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MIEVDDQITKPLNLANSAVLRAVEEEEQQAKCGYKRVAWPPASEERIIREFTPQPQTQSPAPGAGGYYPQAHAPTAAAAAPPQQQYGAPSYDGQQPGAQWQQQQQQQQVPQQQYQPQSQAQAPYQPPQWNQPQQQQQQPSYQASPYQQQQQQQPSYYPQQNGGSTYAQPPYNSYSQPQLPYSQDQTDLQQQQQQQQQQYPGAYAGQDSYRGASPGIITLRKEAPVSQKPAPVYTSQPAAVSYQGGSKLRGDLKWPPPEYKEAAARENEERRQLALGPVCRPRRVNRDYTPFFAKHQLNNGYPSYKVPPGTQHIFG
Protein: Transcriptional regulatory protein DEP1 (P31385)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Transcriptional regulatory protein RXT2
- Transcriptional regulatory protein UME1
- Transcriptional regulatory protein SAP30
- Histone deacetylase complex subunit CTI6
- Histone deacetylase RPD3
- Transcriptional regulatory protein PHO23
- Transcriptional regulatory protein SDS3
- Transcriptional regulatory protein RXT3
- Transcriptional regulatory protein SIN3
- Transcriptional regulatory protein ASH1
Sequence:
MSQQTPQESEQTTAKEQDLDQESVLSNIDFNTDLNHNLNLSEYCISSDAGTEKMDSDEEKSLANLPELKYAPKLSSLVKQETLTESLKRPHEDEKEAIDEAKKMKVPGENEDESKEEEKSQELEEAIDSKEKSTDARDEQGDEGDNEEENNEEDNENENEHTAPPALVMPSPIEMEEQRMTALKEITDIEYKFAQLRQKLYDNQLVRLQTELQMCLEGSHPELQVYYSKIAAIRDYKLHRAYQRQKYELSCINTETIATRTFIHQDFHKKVTDLRARLLNRTTQTWYDINKERRDMDIVIPDVNYHVPIKLDNKTLSCITGYASAAQLCYPGEPVAEDLACESIEYRYRANPVDKLEVIVDRMRLNNEISDLEGLRKYFHSFPGAPELNPLRDSEINDDFHQWAQ
Protein: Cyclin dependent kinase 1 (A0A024QZP7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
Protein: Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog) (Q9Y673)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:10359825}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
- Dol-P-Man:Man
- Dol-P-Man:Man
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- Dol-P-Glc:Glc
- Dolichyldiphosphatase 1
- Dolichol-phosphate mannosyltransferase subunit 3
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Dolichol kinase
- Methionyl-tRNA formyltransferase, mitochondrial
Sequence:
MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIWDSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQKYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKMN
Protein: Large ribosomal subunit protein eL34y (60S ribosomal protein L34-2) (Q9FE65)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL37y
- Large ribosomal subunit protein uL1z
- Large ribosomal subunit protein eL38z/eL38y
- Small ribosomal subunit protein eS28z/eS28y
- At1g43860
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL42z/eL42y
- Small ribosomal subunit protein eS10z
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
Sequence:
MVQRLVYRSRHSYATKSNQHRIVKTPGGKLTYQTTKKRASGPKCPVTGKRIQGIPHLRPTEYKRSRLSRNRRTVNRAYGGVLSGSAVRERIIRAFLVEEQKIVKKVLKLQKAKEKVAPK
Protein: TATA box-binding protein-like 1 (TBP-like) (TBP-like factor) (CeTLF) (B2D6P4)
Organism: Caenorhabditis elegans
Function: May be a general transcription factor. Plays an essential role for RNA polymerase II/ama-1 transcription in early embryos whereby it activates a subset of RNA polymerase II promoters and facilitates the reestablishment of transcription after mitosis.
Subcellular location: Nucleus {ECO:0000269|PubMed:11030349, ECO:0000269|PubMed:11030350, ECO:0000269|PubMed:14726532}.
Interaction partners:
- Prion-like-
- TATA-box-binding protein
- Transcription initiation factor IIB
- B-related factor 1
- HTH TFE/IIEalpha-type domain-containing protein
- BTAF
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 2
- PHD-type domain-containing protein
Sequence:
MQMGDHQMMGNQRYYRTYVQKVMPAQAGGAVSQNATYVQTAGIRTVHHDGNGQQRIVQLPPGVRQIQQNGVGPAYVRQVPGGQPMQVNFGHPGTIAGRNVAVGVQMRPVQGHNVQQGYQRQQVANQIQQQNRAVFMAQNQQGQQQISYAQAQHRQQQQNQQQHHQQPQHFNHPSQQNQMIMQHRQPQMHHNQQHQMVQPQMTRHQMAQHHAQQPHPQIYVPRDMNLAVPLREPSPEPIPVKIEVPDVPPEGTSAANEEPMPDDGDIDIQIRNVVCNYTLPLHIDLRKLAMNTHNVTYEREKGVMMKQKRSPGCYIKVYSSGKVYIVGCRSEADCKRAARSIARHVQRVMGKTKERVSIRNYRVNNVLATCRLPFGIKIEEVAAKYPSESTYEPELSVGLVWRSVTPKATLRIHTTGSITVTGAQSEADVLEVLSKIYPIVLEFRCLERAKGNVAAQKKRKRKAPVNRGPPIKRERFDDSNYRNSGVINNQVYFSDEDEDLYDELDLEE
Protein: ABC transporter A family member 6 (ABC transporter ABCA.6) (Q8T6J1)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MEFGRQLKTLLKKNLLLKGKSKCSICCEIVFPIVIIGVLFAILALIKVTNSDYNSIDVTTFSRRVGPENKLLYGSEGSLNNDQSGVIETMKEQVATARGLTVAEVQDFFMEINDRTLMESFFKNYSMMVYGGVWFNSSTNGGGGGNNNDPIAAGGQFGYNIRLDSDDTADTSETGKVDGGDSSIYLNDNFASIQVAMDQAIFGYFGLDMVLNISGRHYPDPYTELWQEWITGRDAIIKSAGSVFITAALMMFSFRLVTDVVIEKETKIVEAMRMMSLNSLAYFSSWIITSLITSLPVTLLIVVIFKGSQLIYSTSWGIVIITFVLYLITLLLLSFIFSIFFNNSKFCGLLSFVIVIAINICGIFVSKNEFSVSVKLLLSIFSPIAFSNSIYIMSVKDLTMILNLNWDYIVTENQSILMLGIDIIIYIILIWYFEKVIPGEYGTKEKFYFLFTKNYWFGKKRSIGEIDDIESTFDSEDVETIPLKVLKNSTISIRNLRKEFETGDGLRVAVNDLYLDMFEDQIHALLGPNGCGKSTTIGMLTGLISPTSGSAFIRGYDITSQMSKIRPYIGCCLQTDIIWSQLTVLEHLVIYASLKGVEGRNIQREAERMATEVGLAEKMNAPAGSLSGGQKRKLCLGIAFIGRSKIIFLDEVTSGMDPVSRRQVWDFLLKYKKGKTIILTTHYLEEADYLGDRIAIISQGKLRCDGTSLFLKNRFGQGYLLTCNKKLENASNGFNTNQVSEFIKNFIPGASILTDSGAELSYRLPTESLSNFPQFFTEFDLNLSKFSIQTYGISVTSLEEVFISLGQEDSKKLNNNANGNNEFNKQNEMESLKLAIATPSDGINQIQQFKGLLIKRIQQSKKDARSFFLSIILPMALIIGSIILYKSMNDQKQVLFYNNSTQPLTMSLSIYTDSDNTINVPMQLLNNELEWSNLFNNSPYFNKFKYINESINFNDYLIDNYKLSIGAINFTNQPISIDDNNNGQSTNCSYIAYYNSDYIHSFPIHVNLINDALLRKFKNISISVTSMPFDHILTAFEISSSDINASAIIYFVFILMAGFSLMAGSFAGSIAQERTNRVKRLLYVSGCKKHIYWLSNLVWDFFFAFIISILSCSILAGVIKGAFKEQFGSFLLCLILLSCAIIPLGYLMSYKFQTYGKAVGAITAILFVFGLVFTIASLNVRIQAVVNQNSTTQKVADIIDLIFSIISPIFALNRIVFILSGFPGSTRLGTFKVDNYWSFDYLGTPLIVLAGHAVLWNVWILLLDYVPQIKGFFKNPKNLPAPSPPQDEDYDVSQERRRLLNMRPSEEPIQFKNLHKLFPGSGKNPSKTAVYNSTLGIPRGQTFGLLGLNGGGKSTTLSMLSGEIVPSSGEISINGYDVITNREKALGNISMVFQFDALISLLSAREHLWLFSRIKGIKESQIENCVEAFIKMVDLTRIANSGCGGYSGGNKRKVSLSMAMLGNPSVCFLDEISCGCDAVVRRQLWDVISELGKDKSIILTSHSMSEVEALCSRITIMKEGKYTCLNTIQGVKNRFGAGYSIDVKFKKEYLETGIQTILQSIPNCTVLDQHDVMASFEVPNPPGNPIKLSNIFSILSNLPILDDYNVGQTSLESVFLKLTGANHDQRINLYD
Protein: Septin-11 (Q9NVA2)
Organism: Homo sapiens (Human)
Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
Subcellular location: Cytoplasm, cytoskeleton. Synapse. Cell projection, dendritic spine. Cell projection, axon {ECO:0000250}. Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.
Interaction partners:
- Septin-2
- Septin-7
- Uncharacterized protein C17orf47
- Septin-5
- Septin-9
- Septin-6
- Septin-12
- Septin-1
- Septin-10
- Neuronal-specific septin-3
Sequence:
MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNASFT
Protein: Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4) (O01346)
Organism: Drosophila melanogaster (Fruit fly)
Function: Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis. Neurogenic protein implicated in epithelial development. Critical component of a differential oocyte-follicle cell adhesive system.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Beta-1,3-galactosyltransferase brn
- Carboxypeptidase
- Beta1,4-N-acetylgalactosaminyltransferase B
- Beta1,4-N-acetylgalactosaminyltransferase A
Sequence:
MNSTTKHLLHCTLLITVIVTFEVFSGGIKIDENSFTLVDPWTEYGQLATVLLYLLRFLTLLTLPQVLFNFCGLVFYNAFPEKVVLKGSPLLAPFICIRVVTRGDFPDLVKTNVLRNMNTCLDTGLENFLIEVVTDKAVNLSQHRRIREIVVPKEYKTRTGALFKSRALQYCLEDNVNVLNDSDWIVHLDEETLLTENSVRGIINFVLDGKHPFGQGLITYANENVVNWLTTLADSFRVSDDMGKLRLQFKLFHKPLFSWKGSYVVTQVSAERSVSFDNGIDGSVAEDCFFAMRAFSQGYTFNFIEGEMYEKSPFTLLDFLQQRKRWLQGILLVVHSKMIPFKHKLLLGISVYSWVTMPLSTSNIIFAALYPIPCPNLVDFVCAFIAAINIYMYVFGVIKSFSLYRFGLFRFLACVLGAVCTIPVNVVIENVAVIWGLVGKKHKFYVVQKDVRVLETV
Protein: B-cell receptor-associated protein (BCR-associated protein) (A0A8I5ZWB7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367026}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367026}.
Interaction partners:
Sequence:
MSLQWTAVATFLYAEVFAVLLLCIPFISPKRWQKIFKSRLVELVVTYGNTFFVVLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGTAEDGGKLDVGSPEMKLEENKILKTDLKKLKDELASTKKKLEKAENEALAMQKQSEGLTKEYDRLLEEHAKLQTRRRSKDLVFPCL
Protein: 1-aminocyclopropane-1-carboxylate oxidase 3 (ACC oxidase 3) (AtACO3) (EC 1.14.17.4) (O65378)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Enzyme involved in the ethylene biosynthesis. May promote stem elongation by maximizing the extensibility cells, possibly by activating ethylene biosynthesis, in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0).
Interaction partners:
- 1-aminocyclopropane-1-carboxylate synthase 7
- 1-aminocyclopropane-1-carboxylate synthase 11
- 1-aminocyclopropane-1-carboxylate synthase 4
- 1-aminocyclopropane-1-carboxylate synthase 8
- 1-aminocyclopropane-1-carboxylate synthase 9
- 1-aminocyclopropane-1-carboxylate synthase 5
- Aconitate hydratase 3, mitochondrial
- Secreted transmembrane peptide 6
- 1-aminocyclopropane-1-carboxylate synthase 2
- Heme-binding-like protein At3g10130
Sequence:
MEMNIKFPVIDLSKLNGEERDQTMALIDDACQNWGFFELVNHGLPYDLMDNIERMTKEHYKKHMEQKFKEMLRSKGLDTLETEVEDVDWESTFYLHHLPQSNLYDIPDMSNEYRLAMKDFGKRLEILAEELLDLLCENLGLEKGYLKKVFHGTTGPTFATKLSNYPPCPKPEMIKGLRAHTDAGGLILLFQDDKVSGLQLLKDGDWVDVPPLKHSIVINLGDQLEVITNGKYKSVMHRVMTQKEGNRMSIASFYNPGSDAEISPATSLVDKDSKYPSFVFDDYMKLYAGLKFQAKEPRFEAMKNAEAAADLNPVAVVETF
Protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (Q7KMQ6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Protein with SprT-like domain at the N terminus
- RAC serine/threonine-protein kinase
- phosphatidylinositol 3-kinase
- Pi3K21B, isoform B
- Forkhead box protein O
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Insulin-like receptor
- phosphatidylinositol-3,4-bisphosphate 4-phosphatase
- Ribosomal protein S6 kinase
Sequence:
MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSEVHITSDTRSINENKNINYNSYITCKQSSPKFNCGTEDGEEDWESGESTYL
Protein: Single myb histone 1 (Protein SINGLE MYB HISTONE1) (Q6WS85)
Organism: Zea mays (Maize)
Function: Binds preferentially double-stranded telomeric repeats 5'-TTTAGGG-3', but can also bind to the single G-rich and C-rich telomeric strand.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000255|PROSITE-ProRule:PRU00837}. Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837}. Nucleus, nucleolus {ECO:0000250}. Chromosome, telomere {ECO:0000305}. Note=Localized to the nucleolus during interphase. {ECO:0000250}.
Interaction partners:
- 40S ribosomal protein S17-4
- 40S ribosomal protein S19
- 40S ribosomal protein S17-1
- 40S ribosomal protein S19
- 40S ribosomal protein S15-4
- 40S ribosomal protein S15
- 60S ribosomal protein L5-1
- Ubiquitin fusion protein
- Small ribosomal subunit protein uS17
- 40S ribosomal protein S11-1
Sequence:
MGAPKQRWTPEEEAALKAGVAKHGPGKWRTILRDSDFSALLRLRSNVDLKDKWRNLSVTAGGYGSREKARMALKKGRRVVPKLTAEPMDVDVKDMDDAHDTAIDVEPLAMAFESLPTEESPDKSVARLDDLILEAIRKLKEPSGPSKAAIAAYIEDQYWPPADFQRLLSTKLKALVNSGKLIKVNQKYRIAPSPPPSGRIGTKVSSAEGMKAENNNAKRLTKHQVIAELEKMKGMTKEEAAAFAAKAVAEAEVAIAEAEEAARVAEAAENDAEAAKAFLDAVTLSMRNRNAASMMLRAC
Protein: Pre-mRNA-splicing factor 38 (M9PHQ4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU367025}.
Interaction partners:
Sequence:
MDEDYSASSSAGGGKKAGKQHNTLPFWGNESSMNLNALILANIQSSSYFKVHLFKLKTYHEVVDEIYYQVKHMEPWERGSRKTSGQTGMCGGVRGVGAGGIVSTAYCLLYKLYTLRLTRKQINGLLNHTDSAYIRALGFMYLRYTQPPGDLYDWYEDYLQDEEEIDVKAGGGQVSQLS
Protein: AT-rich binding protein ((A+T)-stretch binding protein) (Q86P48)
Organism: Drosophila melanogaster (Fruit fly)
Function: May be a transcription factor for genes having (A+T) stretches in their promoter and/or enhancer regions. Binds to AT rich DNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:11841500, ECO:0000305}.
Interaction partners:
- Defective proventriculus, isoform A
Sequence:
MGFPRILSKNNKIYTKLGEFCLSGDSFWIVCHTCQEELQTQDQFWKHIQDEHNFMHGVAKEHSRTSSYCLTDVEAAAAAATPGSSSQQGATAISVPLALYTCSTKYSEEEQREVEMHEQQVQHQVQQQQAQQQQAQQQQHQQSQQQGHQQHQVQQQQTHQQLQQQRDVAKELAELHANAVAAAAASAAVVSTGEGTTQSNSAIDIKIEPSSLTLTPEMQAAAAAGGTIYHLPQLVPPPVPPPPPGSGFVSVSASTSTSNTVSTTPPNVLQQQQQLNMSVVPSTAMAAAMLAASQEQLPKDSNSTTASAGSAVSSDDGERWYVCDYETCGLKFKYKSRMELHRVVHSKERRFNCELCSASFKQSCNLSTHRKKKHALRGIKSEILPQRF
Protein: Germinal center kinase 3 (EC 2.7.11.1) (STE20-like serine/threonine kinase) (G5EEN4)
Organism: Caenorhabditis elegans
Function: Plays a role in osmotic stress responses by regulating ion homeostasis and by controlling cell volume via the phosphorylation-mediated inhibition of the chloride channel clh-3. In addition, increases gpdh-1 translation upon osmotic stress, likely downstream of wnk-1. Involved in several developmental processes including the tubular formation of the excretory canals, the formation of the intestine and the progression through larval stages. In addition, required for germ line development by controlling meiosis and chromosomal segregation during spermatogenesis. By controlling clh-3 activity, may regulate the development of the excretory canals and fertility.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20595048}. Nucleus {ECO:0000269|PubMed:20595048}. Note=Localizes in the nucleus in intestinal cells. {ECO:0000269|PubMed:20595048}.
Interaction partners:
- Protein transport protein Sec61 subunit gamma
- Translocation protein SEC62
- Translocon Sec61/SecY plug domain-containing protein
- Chloride channel protein clh-3
- J domain-containing protein
- Protein transport protein Sec61 subunit beta
- Serine/threonine-protein kinase WNK
- Solute carrier family 12 member 1
- MO25-like protein 2
- K+/Cl-Cotransporter
Sequence:
MSSSNLAGNTNTTTTSSAASAAAAHSAANASTITSEYSTTQTTTGTFNTDTLSSIGSTSTLHGSQPSQPPPPPPPQVSSPIAAAAAASAALVAQLNPADRWPTEPSAYKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCQTSVDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFKKGKDKKYLVHTLIENLASVPVVAHHSSKKVASGKLRKDAHGNWEFEYDSPQESDDDSDLEDEEREKKKKKASASASGAGAAGAAGGATGGAASGAPSAQEGGGATTPCPETLNMVLRVRNQQRELNDIKFDYTKSADTVEGIAHELVTAELIDCHDLVIVAANLQKLIDFAESKSDRRSITFALNSGVHANEIPDERTLTGFAQISLLD
Protein: Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Q1L8L9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Subcellular location: Mitochondrion intermembrane space {ECO:0000255|HAMAP-Rule:MF_03168}.
Interaction partners:
- Adenine phosphoribosyltransferase.
- Adenosine kinase
- Adenosine kinase b.
- Adenylosuccinate lyase
- Nucleoside-triphosphatase, cancer-related.
- Deoxycytidine kinase.
- Deoxycytidine kinase 2.
- Thiamine pyrophosphokinase
- Ectonucleotide pyrophosphatase/phosphodiesterase 1
- Nucleoside diphosphate kinase.
Sequence:
MAPSTQEDDTVSGIRKGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGQRLKETMDAGKLVSDEMVVELIDNNLDTPACKNGFLLDGFPRTVKQAEMLDDLMEKRSEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFHPPKEHMKDDVTGEPLIRRSDDNETTLRSRLESYHRQTSPLVQYYSARGLHTAIDASQSTDLVFASILAAFSAATCKDLVYFV
Protein: UL3.5 protein (Q77CA9)
Organism: Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)
Interaction partners:
Sequence:
MARVRAGSVFGEARVATVADYTQFLAANRAAAAKLRAAAAAVGESSPDAAARRVRRAPSLRAARRPEGPEAAVPANEERLPPAEARAARLYAAASPARARRSLPSADRRPPPPPTRPFPPNYRTFQ