wanglab/gogpt-training-data huggingface dataset:
Protein: histone acetyltransferase (EC 2.3.1.48) (Q383C5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RuvB-like helicase
- Histone H4
- Histone H4
- Histone H3 variant
- Histone H3, putative
- Histone H2A
- Transmembrane protein, conserved
- Bromo domain-containing protein
- Bromo domain-containing protein
- non-specific serine/threonine protein kinase
Sequence:
MASLAAKKDGGDINGGPSEEEDQLQQLLGTSCCVNLSDSTVKRGFLLEVRYLWLPRLLSGNGTTGVAPQLYGFVRIKDADHRISGWFPIDCIDLKETGGANGATSCGSSYPTNSAAYNSMVVAKSKITHPIISPVYREVTPGMVRTRREGKQLDFFEERLLRDCRTPTTVRYFIYLCKFAFPPWYYAPYGMLNREYDPLAPLSDAEREALRFTEGSTNESIDTNPFIRDAYLCPFSLRIYSTFEQMQHETLRYRAGHLHPPGLEIYRDDTRGFSMFEVNGSRHVTYCRHLFLLGKSFLENKLAGHDVHNYYFYVVCLHHRHYPHYTDDTSAMYFVGYFTWEKQVTDNNLACIVTLPYFMGGGASSGQQNDLSDDRGPVGADTASREGDTPKLGHFGQFMIAASYELAYRRKNVGSPEKPLTDLGAAAYDRYWKRVLIKWMHTLLEGNAAAITVDDDAGDDGQSVTIVVAHENEAKMAAPGALKRPRPGTTDGSGCAEAVRGARVAEGDTLVDTTVRSIAKQVRLEEADVLRTLLQMGVLHLNAEDRSMRVVIPVSFVNREYGKMKKWAHDMTRAEFDPKLLTGRGGPAWLVNTPSPRRHNQHQS
Protein: Exocyst complex component 8 (Q9VBI4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
Interaction partners:
Sequence:
MKEFDDFNFSVEKYTKDLTRECVGGSDLQQRKKEIEAYNETTAATLKQTCKKNYMEFIQTAKEISHLESEMYQLSHILIEQRNILATMTDGKTSSHLKAESLEAESTTATEDLENSHATRAVKEMVQGFNGNLEGKTFLNEGALIELDSNDYRPIQRVFFFLFNDVLIVCKVKHDKRLDFLTEYDPKKIAVINIKDLDGVKNAINIITPDGSKIYQSITAAGKTEWIEKLEEAFRFDQQKKPKKGQAPQPPTRAKQQSKASTPEKETTPQSPGQPKSLEDETPEWLSTASEEIQTLVAQRHFEDAQELIKRTQDFLRNENRKKLPLADAIETKVKQQELKLINVLLKELSNSHNRNLQIALRAAKRPLKILVEMGRYRQASATLLKVCAVSLRVAQREARRNNADISELFFCDLTQVACDFLTAFEKQPACVSALVVWCNAELQYFASQLIKHYLTKGTSLESVAKCVERVRKPSTKLTEIGLDISYHLEGLLRTTLESLIEESKERLLDSVGRTEESWQPYNLQTKSNLKRLLLELDVLGIDVRAQATGDTWINLTQSTVVFIRHFLQLTEYCGCLAKCETLLQSLELLLKELFIAQHSLKPPSDMAVDPNFVMKNKIFLVDNLLPIAIDKFRQISGRQCEGLRELHTKMSRQQGAPVPRQRSVYTTDVF
Protein: Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11) (Q9Z1W4)
Organism: Mus musculus (Mouse)
Function: Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- TGF-beta receptor type-1
- Activin receptor type-2A
- Activin receptor type-2B
- Activin receptor type-1B
- Follistatin
- Follistatin-related protein 3
- Activin receptor type-1C
- Activin receptor type-1
- Angiotensin-converting enzyme
- WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2
Sequence:
MVLAAPLLLGFLLLALELRPRGEAAEGPAAAAAAAAAAAGVGGERSSRPAPSAPPEPDGCPVCVWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
Protein: Interferon-induced protein with tetratricopeptide repeats 2 (Q8IZ03)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVRHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEEAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGEWRIEMWCPLGYC
Protein: Glutaredoxin 3 (Grx3) (P0AC62)
Organism: Escherichia coli (strain K12)
Function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfide bonds in a coupled system with glutathione reductase.
Interaction partners:
- Protein-export protein SecB
- Uncharacterized protein YibN
- Glutaredoxin 4
- Glutaredoxin 2
- Thioredoxin 1
- Glutathione reductase
- Thioredoxin 2
- Thioredoxin reductase
- Glycerol-3-phosphate dehydrogenase [NAD
Sequence:
MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK
Protein: Trk system potassium uptake protein TrkA (K(+)-uptake protein TrkA) (P0AGI8)
Organism: Escherichia coli (strain K12)
Function: Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:2674131}; Peripheral membrane protein {ECO:0000269|PubMed:2674131}; Cytoplasmic side {ECO:0000269|PubMed:2674131}. Note=Peripherally bound to the inner side of the inner membrane via the TrkG and TrkH proteins.
Interaction partners:
- Trk system potassium uptake protein TrkH
- Trk system potassium uptake protein TrkG
- Ribosomal RNA small subunit methyltransferase B
- Methionyl-tRNA formyltransferase
- Low affinity potassium transport system protein Kup
- Sensor protein KdpD
- Nitrogen regulatory protein
- Large-conductance mechanosensitive channel
Sequence:
MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSPDYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKAYYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQNTIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERLFQPSPFFL
Protein: TipA protein (C8V089)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- TapA protein
Sequence:
MASNSRTASVPIAGNTAAMSPTSQRPDTITVKGFKISTQKLPILKAGPIEAMAKKLGIAPPEMIFGDNFVSIEHEKSGWSIHFNALDALDRVDKTGESMLEVAHSKEWQKSRETTHEGIKDVIKPFDWSYSTDYKGTVLSIQGPDFEETSKPIPIELLKRPDPILFFDEVILYEDELADNGITMLSCKIRVMQDRLLLLSRFFLRLDNVLFRLRDTRVYVDFEKSEVIREYQSKECDYGIVRQKLASARDDIPAIMRDPNRLSELLPLVDRRLERVVLDG
Protein: Type IV pilus inner membrane component PilN (G3XD30)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Inner membrane component of the type IV (T4S) secretion system that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility. PilN/PilO heterodimers form the foundation of the inner-membrane PilM/PilN/PilO/PilP complex which plays an essential role in the assembly of a functional T4 pilus. In turn, associates with PilM and facilitates PilM functionally relevant structural changes.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:19857645}; Single-pass type II membrane protein {ECO:0000255}.
Interaction partners:
- Type IV pilus inner membrane component PilP
- Type IV pilus inner membrane component PilM
- Type IV pilus inner membrane component PilO
- Fimbrial assembly protein PilQ
- Type IV pilus assembly protein PilF
- Type IV pilus non-core minor pilin PilE
- Type IV pilus ATPase PilU
- Type IV pilus biogenesis factor PilY1
- Protein PilG
- Type IV pilus retractation ATPase PilT
Sequence:
MARINLLPWREELREQRKQQFLVILGGVLVASAALVFLGDQYFTAAIENQNARNDFLRKEIVVLDARIKEISELKSRRQQLLERMKIIQDLQGNRPIIGRVFDQLVRTLPDGVYFTDLKMTGKNIAIAGAAESNNRVSNLMRNMDASEWLTAPTLNEVKAVTQGAVDQANVFQLTVQQTQPGEEDAKAKHGVAQGAKK
Protein: Peptidoglycan-N-acetylglucosamine deacetylase PgdA (Peptidoglycan GlcNAc deacetylase) (EC 3.5.1.104) (Peptidoglycan N-deacetylase) (PG N-deacetylase) (Petptidoglycan deacetylase) (PG deacetylase) (Q8Y9V5)
Organism: Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Function: Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan (PG) (By similarity). Deacetylates also N-acetylated PG. Does not deacetylate N-acetylmuramic acid (By similarity). Confers host lysozyme resistance. Critical for virulence and escape from innate immune response of the host. Required for intracellular survival of bacteria in macrophages of the host. Required for successful host colonization. Controls the production of inflammatory mediators in the bone marrow derived macrophages (BMMs) of the infected mouse (By similarity). Suppresses Toll-like receptor 2 (TLR2)-dependent secretion of interleukin 6 (IL-6) and interferon-beta (IFN-beta) in the macrophages of the infected mouse. May decrease accessibility of pattern recognition receptors (PRRs) such as nucleotide-binding oligomerization domain protein (NOD) 1 of the host to the bacterial cell wall components. Protects cells from autolysis induced by lysozyme or by other autolysis-inducing agents (By similarity).
Subcellular location: Cell membrane {ECO:0000305|PubMed:29215169}; Single-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:29215169}; Extracellular side {ECO:0000305|PubMed:29215169}. Secreted, cell wall {ECO:0000250|UniProtKB:A0A3Q0NBH7}.
Interaction partners:
- Lmo0529 protein
- chitinase
Sequence:
MKIRWIRLSLVAILIIAVVFIGVIGFQKYQFSKSRNKVIMQMDRLMKDQDGGNFRRLDKKENGVEIISYIPKTTEKKDNEIIQKEIGKATDAEVKKLNRDKETQGIIFYTYQKHRMAEQAISYKAVQSEYVKEGRTKFVLKDKKDICKNIVTDAETGALLTLGEVLIKSNQTKLNLKTAVEEELIKTGDFSLKDVGNLGKIKSLVKWNQTDFEITNSEIILPVKIPGAPEPKKVKVKLADIASSVNKRYLPSSVKVPEVPKAKTNKRIALTFDDGPSSSVTPGVLDTLKRHNVKATFFVLGSSVIQNPGLVKRELEEGHQVGSHSWDHPQLTKQSTQEVYNQILKTQKAVFDQTGYFPTTMRPPYGAVNKQVAEEIGLPIIQWSVDTEDWKYRNAGIVTKKVLAGATDGAIVLMHDIHKTTAASLDTTLTKLKSQGYEFVTIDELYGEKLQIGKQYFDKTDSRMVK
Protein: Kinesin-like protein (Q585N4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Kinesin, putative
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin, putative
- Kinesin, putative
- Kinesin-like protein
- Kinesin-like protein, putative
Sequence:
MAKPLSGKAAPKNISVFLRVRPPVPRELKGGTFNNLVCDPSDPQRVTITRGGSARKGTKSFLFNRVFDPECTQQTIYNEVARGAVDAAFDGQHGVLFVYGQTGSGKTFTISNNDPEKPGVLQQSLRDIWDRFQADTEYDYSCTVSYVQLYNEMLTDLLDPQGGRVRIQLGPEGRGDVVLVTEASGASIERKVESYEDCLKYFYEGMDRKEMTSTKMNNTSSRSHTVFNFNLTRSAKVKTVDLSSAKANNEPVIALQGRLVVCDLAGSERASRTNAEGKTLDEATHINGSLLVLGKVVAALTESGSQHAPFRESKLTRILQYSLLGNGNTSIVVNCSPCDDSTEETLGAIMFGQRAIQIKQDAKRHEILDYKALYYQLLADLDSKNDRTLETALSEERTAYEDRIRVLEERIKILTSENDMLRRESSQLGGTGPVSGTSTASGAAAAAVAMGGDDANDWRSLTMKMRRAIEKLDADLKRTDKERVELAQFLALEKNKVNVLAQKLRAESLKHIMENKELTQRVTELSIDNAKLKGTDYISFQPSAACEDALPLSLDSPRRGTPSSGLSQSINVGDAYLQEQLDKANRQLRVLNEERVELIVYQMMASKAIRLLHAEKTSLANHLEKLKA
Protein: Guanine nucleotide-binding protein subunit beta-like protein (Q38C12)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMALELLAQQYLPISPRHLSLLTLDGGSPAAVVAVSPAYDNFNRVFFLEWDYPTETGNFRLIHTEMPGVGVNALSLMLSQDGVVHCVVQCASKGKEESPKTYLLRRTEDAGNSDSDTSDNGNEEDTAVKYKILPKVMEDDSRSWTVATRLYRGNGGVRDSNNSSRVVAACGGERGEPNALKMMYLSGTRLSVQQSVELPVLSTFPLLRLCEIDGDVSSLLALCHHAVLEIDPRLKQQESVVRAWKWTPRDPLTAFAVKDNSIVAGTEDGVLVLWDLRFAAVHEKGSKAVDHSVSCGAPITGLHMPHSSSVLSCQADGAVLTWERCSTSSINNINEACFVPRRIPALPPTFVGTPGCVGMAAEDNIAVVADESGVLSIFSMS
Protein: Histidinol-phosphatase (HolPase) (EC 3.1.3.15) (P38635)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Histidine biosynthesis trifunctional protein
- Histidinol-phosphate aminotransferase
- ATP phosphoribosyltransferase
- DNA repair protein RAD16
- Imidazoleglycerol-phosphate dehydratase
- General control transcription factor GCN4
- Imidazole glycerol phosphate synthase hisHF
Sequence:
MHSHHSHSGDYSAHGTDPLDSVVDQVVNLNFHTYCLTEHIPRIEAKFIYPEEQSLGKNPEEVITKLETSFKNFMSHAQEIKTRYADRPDVRTKFIIGMEIESCDMAHIEYAKRLMKENNDILKFCVGSVHHVNGIPIDFDQQQWYNSLHSFNDNLKHFLLSYFQSQYEMLINIKPLVVGHFDLYKLFLPNDMLVNQKSGNCNEETGVPVASLDVISEWPEIYDAVVRNLQFIDSYGGAIEINTSALRKRLEEPYPSKTLCNLVKKHCGSRFVLSDDAHGVAQVGVCYDKVKKYIVDVLQLEYICYLEESQSPENLLTVKRLPISQFVNDPFWANI
Protein: Monomethylamine corrinoid protein 1 (MMCP 1) (O30641)
Organism: Methanosarcina barkeri
Function: Acts as a methyl group carrier between MtmB and MtbA.
Interaction partners:
Sequence:
MANQEIFDKLRDAIVNQNVAGTPELCKEALAAGVPALDIITKGLSVGMKIVGDKFEAAEIFLPQIMMSGKAMSNAMEVLTPELEKNKKEGEEAGLAITFVAEGDIHDIGHRLVTTMLGANGFQIVDLGVDVLNENVVEEAAKHKGEKVLLVGSALMTTSMLGQKDLMDRLNEEKLRDSVKCMFGGAPVSDKWIEEIGADATAENAAEAAKVALEVMK
Protein: 7-deoxyloganetin glucosyltransferase (EC 2.4.1.324) (Iridoid 1-O-glucosyltransferase) (UDP-glucose glucosyltransferase 6) (CrUGT6) (UDP-glycosyltransferase 85A23) (F8WLS6)
Organism: Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
Function: Iridoid glucosyltransferase acting exclusively on 7-deoxyloganetin. No activity with 7-deoxyloganetic acid.
Interaction partners:
Sequence:
MGSLSSSDYSKKPHAVCIPYPAQGHINPMLKLAKLLHYKGFHITFVNTEFNHKRLLKSRGSDSLKGLHSFQFKTIPDGLPPSDVDATQDIPSLCESTTTHCLVPFKQLLQKLNDTSSSEVPPVSCVVSDAVMSFTISAAQELDIPEVLFWTPSACGVLGYMHYAQLIDKGLTPLKDASYFSNGFLDQVLDWIPGMEGIRLRDLPTFLRTTNPDEYMIKFILQETERSKKASAIVLNTFQELESEVIDSLSTLLPPIYPIGPLQILQNQVDDESLKVLGSNLWKEEPECLEWLDTKDPNSVVYVNFGSITVMTNDQLIEFAWGLANSKQNFLWIIRPDLISGESSILGEEFVEETKERGLIASWCHQEQVINHPAIGGFLTHNGWNSTIESISSGVPMICWPFFAEQQTNCRFCCNKWGIGMEINSDVKRDEVESLVKELMVGEKGKEMKKKALEWKNIAEVTTTKPDGSSYSNLEKLIKVLKSKPSH
Protein: Cyclic nucleotide-binding domain-containing protein (O61827)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Cyclic nucleotide-binding domain-containing protein
Sequence:
MSSAEVSDSESLLDIDISQYEVVEKYLEDEELESFDIYPSGWTICKDILHDSFHRLLYFYVPFNSKYYYIWSFFVSFGVMYNMFAMVIFIFADIKTQYFWNWIFLNVMFDMVFIVDIFVQSRLTYLHEGEEVKNTKKLRKNYFFQKLKVANDIFCLLPLDFLLFFDDSMSLVRTIRIVKVIRLMDFVQRTQQQTTFPRAFKIILLAVSCIVLFHWNACLYFLFSLYEGITEESQTEFGFSYYKVFEPVFPTCQAYYDENCWFGEDIDHTLDLDDVRDSYKKEMAEYWKDKHYRWTTGNFSREYSMSIYWSALTITTCGQQPWPSTSSQNSLEVFDTLIGVLVFATIIGSVGSVVTQMSQTVNEFRQMMDGIKFYMKYREVNSAIQERALSCFMYLMAHNQLDDEEGILSLLPPRLQANIAANLHMETLQNIQIFALCESRFMHEVVLLVKQQVFSPNDYLCRKNEKAKELFIVKKGKLRVIDDDTGEEMGELTEGATFGELSIVYVKGNLLGTRRCCSLQSVGFSDIYVLYRDDVSRLLQEFPQEYKTIVMNARNLLHSRGLLETTELGEMCDPSDHEEADDLVLEEMSVVEQLNRLNGIIDGLNGNMNVMILSFSNSCSYYKQKITGLEDTFNQNREQIRSDFKNGLYIDFIDY
Protein: Nicotinamidase 1 (AtNIC1) (EC 3.5.1.19) (Nicotinamide deamidase 1) (Q8S8F9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Prevents the accumulation of intracellular nicotinamide, a known inhibitor of poly(ADP-ribose) polymerases (PARP enzymes).
Interaction partners:
- Nicotinamidase 3
- Nicotinate phosphoribosyltransferase 2
- Nicotinate phosphoribosyltransferase 1
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase
- UDP-glycosyltransferase 76C4
- Probable inactive nicotinamidase At3g16190
- Glutamine-dependent NAD
- Nicotinamide adenine dinucleotide transporter 2, mitochondrial
- Quinolinate synthase, chloroplastic
- Nicotinamide adenine dinucleotide transporter 1, chloroplastic
Sequence:
MANHETIFDQLKKQIPVDEEEPLILNRDSSVGLVIVDVVNGFCTIGSGNMAPTKHNEQISKMVEESAKLAREFCDRKWPVLAFIDSHHPDIPERPYPPHCIIGTEESELVPALKWLESEDCATLRRKDCINGFVGSMESDGSNVFVDWVKEKQIKVIVVVGICTDICVFDFVATALSARNHGVLSPVEDVVVYSRGCATFDLPLHVAKDIKGAQAHPQELMHHVGLYMAKGRGAQVVSKISFET
Protein: Neuron navigator 2 (A0A8I6A8E6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSVMLWRWEQNNSTMKLIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANDKIEDINGCPKNRSQMIENIDACLNFLAAKGINTQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQQPEKQHLSSSPLPPAGSQVAGAPSQCQSGILQQQGLATPQAPCQPLQPASHQQAKTQAEMQSRLPGPTARVAAAGSEAKTRGGSTAANNRRSQSFNNYDKSKPVPSPPQPAPPSNHEKEPLASSASSHPGMSENVPASLESSPSIPVNCSSSAIPQPSMTSKPWRSKSLSVKHSATSSMLSVKPAGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGSASRDTSCERLEILPSFEESEELEVANRAPPTAGPASSSPKIALKGIAQRTFSRALTNKKSSPKGNEKEKEKQQREKEKETGKDLTKRVSVTDRPDLKEEPKEELSGVVVTEMPKKSSKIASFIPKGGKLSSTKKEATAPSHSGIPKPGMKNMPGKSPSAPIPPKEGERSRGKLSSGLPPQKPQLDSRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSIGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSAGVSMEPSHYTKSGQPALEELTAEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFISAEAGRYVYSAPLRRQLASRGSSICHVDVSDKVGDEVDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRRNLDVQTDAEKHSQVERNSLWSGDDIKRSDGGSDSGVKMEPGSKWRRNPSDMSDESDKSVSGKKNPVLSQTGSWRRGMTAEVGITMPRTKPSAQTGTLKTSGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKTLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAPNQDDGYLSLSSRTNLQYRSLPRPSKSNSRNGAGNRCSTSSIDSNMSSKSAGLPVPKLREPSKTSLGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPATQPVSNSTQATLQPGTKYTDVASPTLRRLFGGKPTKQVPIATAETMKSAVVISNPHATMTQQGNLESPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSGPSNSLTWGTSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGGLSHNSSPGPVASTKEDSLMPFVRTSSVKTTLSERYTPTSQLRTQEDTKEWFRSHSAGGLQETATNSPFSSGSSVTSPSGTRFNFSQLASPTAVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSAQATDLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNAHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSLGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEAMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTILVTVKGLTENSLDSLVFESLIPKPILQRYVSLLTEHRRIILSGPSGTGKTYLANRLSEYVVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNAELVKIINWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSLPREGSTSKQVPPSDTEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL
Protein: Large ribosomal subunit protein eL22 (60S ribosomal protein L22) (Q389Z6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 60S ribosomal subunit protein L31, putative
- 60S ribosomal protein L27, putative
- 60S ribosomal protein L4
- 60S ribosomal protein L35A, putative
- 60S ribosomal protein L19, putative
- 60S ribosomal protein L29
- Large ribosomal subunit protein uL5
- 60S ribosomal protein L39, putative
- 60S ribosomal protein L2, putative
- 60S acidic ribosomal protein P0
Sequence:
MVAVRAKVGSRGFTRQRQLAKGKKVFKIDCSIPASDGIFSDDILSNFQQYFQDNVKLNGRKGKLTSKVRVNMRENILSITTTMAYRKKYFKYLTKKFLKKKDLRDWIRILAKGKDTYQLKYFNIQDQEEA
Protein: Paired amphipathic helix protein Sin3-like 1 (Q9SRH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a transcriptional repressor. An histone deacetylase (HDAC) activity is required for transcription repression. May play a role in telomere stability.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00810, ECO:0000269|PubMed:19962994}.
Interaction partners:
- Histone deacetylase 19
- Histone deacetylase 6
- Zinc finger CCCH domain protein
- Paired amphipathic helix protein Sin3-like 3
- Paired amphipathic helix protein Sin3-like 2
- Histone deacetylase 9
- Protein ALWAYS EARLY 2
- Histone deacetylase 7
- Histone-binding protein MSI1
- Cytochrome P450, family 705, subfamily A, polypeptide 18
Sequence:
MKRIRDDVYASGSQFRRPLGSSRGQLCGQSPVHGSGDTEEEEEGGSRRVSQKLTTNDALSYLREVKEMFQDQREKYDRFLEVMKDFKAQRTDTGGVIARVKELFKGHNNLIYGFNTFLPKGYEITLIEEDDALPKKTVEFEQAINFVNKIKMRFKHDEHVYKSFLEILNMYRKENKEIKEVYNEVSILFQGHLDLLEQFTRFLPASLPSHSAAQHSRSQAQQYSDRGSDPPLLHQMQVEKERRRERAVALRGDYSVERYDLNDDKTMVKIQREQRKRLDKENRARRGRDLDDREAGQDNLHHFPEKRKSSRRAEALEAYSGSASHSEKDNLKSMYKQAFVFCEKVKDRLCSQDDYQTFLKCLNIFSNGIIQRKDLQNLVSDLLGKFPDLMDEFNQFFERCESITDGFQRLAGVMSKKLFSSEEQLSRPMKVEEKESEHKPELEAVKETEQCKKEYMGKSIQELDLSDCECCTPSYRLLPADYPIPIASQRSELGAEVLNDHWVSVTSGSEDYSFKHMRRNQYEESLFRCEDDRFELDMLLESVSSAARSAESLLNIITEKKISFSGSFRIEDHFTALNLRCIERLYGDHGLDVIDILNKNPATALPVILTRLKQKQGEWKKCRDDFDKVWANVYAKNHYKSLDHRSFYFKQQDSKNLSAKSLLAEIKELKEKSQNDDDVLLSISAGYRQPINPNLEYEYLNRAIHEDMFKVVQFSCEELCSTKEQLSKVLRLWENFLEAVLGVPPRAKGTDLVEDVVINPKTLDVNHSTSPNGEAAVSSGGDTARLASRKLKSAANGDENSSSGTFKHGIGLLNKDSTGKENLEDVEIANRDGVACSAVKPQKEQETGNEAEKRFGKPIPMDISERAAISSISIPSGAENNHCVVGKEVLPGAHEIQAKPSDTLTDIHHDVDSIETVHSTQGGDVGNSIVLANGLRSDSSKGTRNSDDPEGPSRNEKEEGELSPNGDFEDNFGVYKDHGVKSTSKPENSAEAEVEADAEVENEDDADDVDSENASEASGTESGGDVCSQDEDREEENGEHDEIDGKAESEGEAEGMDPHLLEGESELLPQSERVLLSVRPLSKHVAAVLCDERTKDLQVFYGNDDFYVLFRLHQILYERILYAKRNCSGGELKSKNLKDTNAGDPYARFMRVLYGLLDGSAENTKFEDECRAIIGNQSYVLFTLDKLIYRLVKQLQAIVADEMDNKLLQLYEYEKSRKPGRVIDSVYYENVRVLVHEENIYRLECSSLPSRLSIQLMDNIIEKPEAYAVSMDPTFASYMQTELLSVSSGKKEEGHDIVLQRNLTGLYDLCKAMEGVEVVNGLECKMSCSSYKIAYVLDTEDYFHRKKKKKKTEQLWQRNKVRVERFHRFLSA
Protein: Dual specificity protein kinase Ttk (EC 2.7.12.1) (Mitotic checkpoint serine/threonine-protein kinase Mps1) (Monopolar spindle protein 1) (Protein nightcap) (Q8AYG3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Phosphorylates proteins on serine, threonine, and tyrosine (By similarity). Involved in mitotic cell cycle checkpoint control. Required for fin and heart regeneration. Required to prevent chromosome segregation errors during meiosis.
Interaction partners:
- Mitotic spindle assembly checkpoint protein MAD1
- Kinetochore protein NDC80 homolog
- BUB1 mitotic checkpoint serine/threonine kinase
- Kinetochore protein Nuf2
- MAD2 mitotic arrest deficient-like 1
- Kinesin family member 11
- Cell division cycle 20 homolog
- Discs, large
- HORMA domain-containing protein.
- Condensin complex subunit 3
Sequence:
MDEEESTERQMQIAMLCQKLAMMKQLFNEDDTDYINQAISSNSPDTCRTFLSNLEKKGNPQADPSLLSKLMDSYTRVFSSMPLGKYSQNESYAKMLVRFAELKAIQDVNDAQTSFDIARSHCKDFAFVHVAYAQFELLQGNMKKCTMILQKAFEMNAKPRHVLEAAVRNLKTGKRQLLSHEDKENLSVSALDHTQGSRRSDGTCELKPSNTFLHSDQKFSPQEENGPVWRTGSQHRRTAMAERVPMVPLSIPENETSDSDCAQKAEAPFTHSSGFSRQTSGSSVRSAFSLCSSKKGTPDGDSYSLNIKPPVISPDYLREDIEEGHTITALLNRAEKRETARTEETTDINQIISTNSTEGCQAFLKNLEKRADPHSDAAFLSKLLDCYSKVFARFPLAEHCKTESYARMLVRYAELKGIEDPEDAADDFSIARSHCKAFAFVHIAHAQFELSRGNSRKSVSILQKALSSNARPIELLQTAIRNLKSGKTLLLPAEHQESSEAENVEAQNGMKREENPVKAPEDHQKPFSKETSSEWKIPALITKHTSPEDRKAPVEPVSSSSSHHAVRTPAPLRLNPSLSCQTPNYRQPNPNSFVTPVVKQRPVIVSVPATAQKMCPTALPCTPQSGVSYIQPPTQTPSSAFSNESITIKGKQFFIFKMIGRGGSSKVYQVFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEITSSYIYMLMECGHLDLNTWLRNRKTVKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGSLKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSSNGKPGSKISAKGDVWSLGCILYCMTYGKTPFQNITNQISKIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQLQPQPAPEPAETSSSDFKRILNELVALQSPNSIARAASNLAMMCNSGRKLDVSECVKSSSQTLWK