wanglab/gogpt-training-data huggingface dataset:
Protein: Serine repeat antigen 2 (EC 3.4.22.-) (O96166)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Uncharacterized protein
- Serine repeat antigen 3
- Cysteine proteinase falcipain 1
Sequence:
MKFHISFFLILYIVFFKNTIKSETTTDESATGSLSSDGSRVTTQARIEKPKQQPTLPTLAQETQPQQQQQQKEVGSGIGAEQKVESARPGAEVSQSDVERAGRSSGTGGSVGTKISPGSQGQGKVAGPQLPRLPQLPQSFEQSRNQQSSPVTPKRNGISPTNAKSPESVLPPAQSFTNLNKSTIPHTIPIKSSFLKYYKGVKITGSCGVQFQLVIVPHLFIYVETKENNIQLEPRFMKLNERIDFEKDKSNLKNKCDVNKKQSFKFILYLQHDLITIKWKVYEEKPDTTTRIAPGQVDLNVDVKRYKLPKLDQPVISIQIHSLAQDGETYLMESKDYNLEDQIPEKCEAIASDCFLSGNVDIEKCLQCTLLVIKADKNDECLKYVSKNVKDRFEEILTKGEDDADSDEYDFIAPANYILKNIYKKNDTNGKKELLHFKDINNNLKLELINYCNLLKDNDVSGILTYEKLGNVQDIFNNLTKLLEEHKEENNYVLYHKMKNEVLCLKNANDWMKNKTGLVLPQLKYSLNKFNKNKENYIKENIFEEDENGIVDLTKFPVDTSYSSYNYADSLYCNREYCNRLKDHNNCISKINVEDQKNCALSWAFASIYHLETIKCMKGYEPLNASVLYVTNCLKNKNNDVCTEGSNPLVFLETIEEKGFLPTESNYPYDQSKVGDVCPQVQNDWDNVFENTKVLEYNNAPFSVGTKGYIAYESEVFQKDIDSFVKLIKDEIMNKGSVIAYVKAKNVLGYELNGKKVQNLCGDKKPDHAVNIVGYGNYINNKGEKKSYWIVRNSWGKYWGDDGYFKVDMYGPPTCEDNFIHSVVVFNVEVPVNENFDKKEHDIYKSYLKNSPDFYHNIYYKNYNFENYVSPISTWSEVLHNTLYNNNLIWGQETTDPIGEGKLPASEAGHLRGEGKGNSEENQGQRSNANGAISSNQSTGGKITKQGESKDDGVALPVSTDGKPNTSSSVVDTNDQRSLPNPRATSLQPPSVQIPNHEGTSAPGNSRTPSIVSPTAAEKSRKAQIFHVLKHIKNSRIKMGLVKYDNSDNIGGDHVCSRTYAVNPEKQEECVKFCEENWENCKNKPSPGYCLAKLKNTNECFFCYV
Protein: Negative regulator of sporulation MDS3 (MCK1 dosage suppressor 3) (P53094)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Negatively regulates early sporulation-specific genes. Seems to exert its function by positively regulating the Ras/cAMP pathway. Required for growth under alkaline conditions. Acts synergetically with PMD1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Cell division control protein 25
- Uncharacterized protein YBR225W
- SIT4-associating protein SAP185
- Serine/threonine-protein phosphatase PP1-1
Sequence:
MPLLQPSTCFCYPLKLPPLPLTSDSNEFDECARKRLTLDYRTGSAVTLTRSNIFVHGGLTIPLNLPVVNSMQLQKELILFFAKEKNNGSSFRNLNEWISKETFFLDLMSRTWYRVKTSFDQRTEELLKAESSSAKADNDTNEIRTDIKKGKSLESPLKERLFHSLCYLDGCLYIFGGLTVSPQSGYELIATNELWKLDLNTKKWSLLSDDPQIARRFNHTMHVKNENNDNRDTKLIIVGGLNNMDQPVKKIDIYNISQNCWQSETIPKQPMEITTNVNGIPLALSKDQNFSILVENNEANVPALAFYMRSDQIDEYLGKDSSKIKENSPIVALPLLSESQGIRMPSNPALPKKLLNVPYELLAPTGDYFGFNIIIGGFHPNYQSSNFHCFIYDINSGKWSRVATACPDCDINKHRFWRVFVWKSHHQTILLGTKTDDYYSPSVQRFDHLSTFGLPLVNIFNKTIQLPHHKISASSLPIPIENFAKHKDTPLKKVSFTSSATSQFENYIRYIAPPLEMSSIQSVFPPYAMVLGKDALEIYGKPLSDFEFITSEGDSIGIPCYLLRKRWGRYFDMLLSQSYTKVCADYETTDTQSTLIKFSPHSSRNSSKAVRQEGRLSSSGSLDNYFEKNFPIFARTSVSEAQNTQPQVANADAKAPNTPSTSDEPSSSSSSDLYSTPHYQRNNDEEDDEDPVSPKPVSKSNSIYRPIRKTESSSTTSSSNGMIFRVPFKEKAAVTSNTEALLESNLSLQELSRRRSSLMSIPSGELLRSSISEAEHQRRASHPLTSSPLFEDSGTPCGKQLQQLQQHTIQNPHNHLSPRRFSRSARSSISYVSSSSDRRGNSISSRSTSDSFGTPPVLGVLNVPLPPQTREPNEPPPPCPAMSTGSNTRRSNTLTDYMHSNKASPFSSRRSSHIGRRSSTPETENAFSATPRASLDGQMLGKSLKEGSTSQYTQPRMNSFPKANETIQTPTSSNNEWSRQSVTSNTDSFDSLQSNFALELEPLLTPRSLYMPWPTSTVRAFAEFFYTGQVNSKWLLAPVALDLLVMAKIYEIPLLYKLILEVLYSILAKKEESLSLICTSLMETFRTKTLNSYKGDEEKTNTYLTSNDNYQELLKLKVSLENIDNGYYDPDLLRKQSRAQSSSTQESSGSANGEKTATGAGSLETSSTNVPTVFAGGPRDSHNSVGSIGFPNSMNIQGSRRSTSGFSPRVKMKSSLSKEIDPKTFYEEYEPKEGKSFDDNDDQQTNIGSFNLHLFDMNYGSISSSSTNSISSSDLEEKEEQEQLQDLLEIEREDSAEILDARFRNKEDDKVTKDISNDKKRNYLPHEKNNLKAKEGKETRDVREEEEEFDFGLGMLSLNKIKREAKHVDKVDDSVDPLFKSSAFPQSPIRAYGSTTRTSSASGKPFRDNRSFNAFSVLTLENMASANALPPVDYVIKSIYRTTVLVNDIRLMVRCMDCIELSKNLRALKKKTMEDISKLKGISKPSP
Protein: Xylosyltransferase oxt (EC 2.4.2.26) (Imaginal disk type I) (Peptide O-xylosyltransferase) (Q7KVA1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Beta-1,4-galactosyltransferase 7
- Hexosyltransferase
- DEAD-box ATP-dependent DNA helicase Fancm
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- DNA repair endonuclease XPF
- Hexosyltransferase
- Crossover junction endonuclease MUS81
Sequence:
MEQSVSARWLKRYRAFFLILLLIVAIQLFLAYKSLDIVGGGSGSGFDAAEAPASPPPPHAQARVQPPARTKLTAQQLGFQPECDILAREAISALQRAKTKDCREHIAQIACAIQAGRFYAPQLRSSCPAGNHTANVSLGCFKDEKDRRLLAGYYSSSKTSNSPAKCVELCLQSGYPYAGVQYGRECFCGYDPPPKASKLPDSSCNTKCLGNAKEICGGFYAMNIYETGIAKFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLLELESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDFPVKTLDKLVDFLSANPGRNFVKGHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKLPAGIQVDGGSDWVALSRPFVGYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYVDNNLHVTNWKRKQGCKCQYKHVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWLYGPYTSEYANLHGYWQSLYHHEDVHGSGDDLARSIGDSVMRLSARQAKLYPLELIELTHYLHRDQYKGFLVRYRARGSTGKPLHLETRVRPTQQGKLARNARFSKRLRNFEVSTDFDQKEQIARNFGKLLGPQSDLLLSYTLQANADSGAASHSYNLTLLWIDPLGRLQDFNELHVEDSTSDVINHSKTLLKHPITPGIWTAKLIGRNSIYAQLKFLIAPLAYYKGYPLAKSSDAEALNAGLTVALPEDFEMPVEWQQHLQTDDEQFTMREESLAKGKMLGQELHSWIDGLVGQFFQLRESCVVEADSEVSLPLCSDAPWSSLAPDPKSDVDALLK
Protein: Uncharacterized protein YNL146W (P53906)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uncharacterized protein YOL097W-A
- Probable phospholipase YOR022C, mitochondrial
Sequence:
MSNTKHTTSHHMELKRIIILTLLFILIMLIFRNSVSFKMTFQELLPRFYKKNSNSVSNNNRPSSIFSENLVDFDDVNMVDKTRLFIFLFFSFIITIPFMV
Protein: Motile sperm domain-containing protein 3 (Q8BGG6)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MRRGAPQDQELVGPGAPGRGSRGSPPSSGPVVPVLVFPPDLVFRADQRSGPRQLLTLYNPTGTALRFRVLCTAPAKYTVFDAEGYVKPQSCIDIVIRHVAPVPSHYDVQDRFRIELSEEGTEGRVVGRKDITSVLRAPAYPLELQGHSEPTPNPGPPVWTGLTPARHLQENAPQQLATSSFLLFLLAGVISVAFLLLPLQDELGSQLPQVLHVSLGQKLVAAYVLGLLTMVLLRT
Protein: Bifunctional UDP-glucose 4-epimerase and UDP-xylose 4-epimerase 1 (EC 5.1.3.2) (EC 5.1.3.5) (UDP-D-xylose 4-epimerase) (UDP-L-arabinose 4-epimerase) (UDP-galactose 4-epimerase 1) (UDP-glucose 4-epimerase 1) (AtUGE1) (Q42605)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the interconversion between UDP-glucose and UDP-galactose and the interconversion between UDP-arabinose and UDP-xylose. Plays a role in D-galactose detoxification.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16644739}.
Interaction partners:
- ADP-glucose phosphorylase
- UDP-sugar pyrophosphorylase
- UTP--glucose-1-phosphate uridylyltransferase 2
- UTP--glucose-1-phosphate uridylyltransferase 1
- Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1
- Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3
- Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2
- UDP-sulfoquinovose synthase, chloroplastic
- UDP-glucose 6-dehydrogenase 3
- Galactinol synthase 5
Sequence:
MGSSVEQNILVTGGAGFIGTHTVVQLLKDGFKVSIIDNFDNSVIEAVDRVRELVGPDLSKKLDFNLGDLRNKGDIEKLFSKQRFDAVIHFAGLKAVGESVENPRRYFDNNLVGTINLYETMAKYNCKMMVFSSSATVYGQPEKIPCMEDFELKAMNPYGRTKLFLEEIARDIQKAEPEWRIILLRYFNPVGAHESGSIGEDPKGIPNNLMPYIQQVAVGRLPELNVYGHDYPTEDGSAVRDYIHVMDLADGHIAALRKLFADPKIGCTAYNLGTGQGTSVLEMVAAFEKASGKKIPIKLCPRRSGDATAVYASTEKAEKELGWKAKYGVDEMCRDQWKWANNNPWGYQNKL
Protein: Prickle-like protein 2b (Prickle2) (Q7ZZC4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MPLEMEKTVTKLMYDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSSLPEDKVPYVNSPGEKYRIKQLLHQLPPHDNEVRFCNSLDDEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPQCFVCSMCDELLVDLIYFYQDGKIFCGRHHAERLKPRCSACDEIILADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCTCFESLYAEYCDSCGEHIGIDQGQMTYDGQHWHATEACFSCARCKKSLLGRPFLPKQGQIFCSRACSVGDEQNGSDSSDSAFQSARSREARRSSSKSNKSSTGGSGGDGHQSGKASAMRFSADVDPLSLQMDLLSLSSQTPSLNRESPSWKTQAEMFGYEGRNELSTNPLHLLSQCNIRTSYSSNLSPGHLSDPRPKEPASSKRPPVSALKGKSLNENWFQQGPEDYYPPALRTQASFNEVPHNSFMDKRSVSLHVFQREKEKDVGPQMSRSRNPISALGFSEQLTPLEQTPRGSMESLALSNATGTSADGGSKRQEHLSRFSMPDLSKDSGMNVSEKSNMGTLNSSVQFHSSESLRSLNSAQPYLELEAPVQVRFPVQYPREPSGINALPPGFAYQEEDRVSLVSNANNARLPPMSERTRRRSIDHEEPRRRHHHHRSRRSRRSRSDNALNLVAERRPALKRSQLHAREDYDQFPLPRGSRDTYGSGRLRQQPFRPCPRTTSDLTLQNPALHRHQGPYSWDQYDYDDDWCSTCSSSSESEDEGYFLGEPIPRPIQLRHMTSEELLRKYNSSGLGASGQFGSRGQLHMRKRRKSKNCIIS
Protein: Antitoxin MazE5 (P9WJ89)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5.
Interaction partners:
- Probable endoribonuclease MazF5
- Conserved protein
- Putative antitoxin VapB18
- Antitoxin MazE7
Sequence:
MKTARLQVTLRCAVDLINSSSDQCFARIEHVASDQADPRPGVWHSSGMNRIRLSTTVDAALLTSARDMRAGITDAALIDEALAALLARHRSAEVDASYAAYDKHPVDEPDEWGDLASWRRAAGDS
Protein: Serine incorporator 3 (Axotomy-induced glyco/Golgi protein 1) (AIGP-1) (Axotomy-induced glycoprotein 1) (Membrane protein TMS-1) (Tumor differentially expressed protein 1) (Q9QZI9)
Organism: Mus musculus (Mouse)
Function: Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12486168}; Multi-pass membrane protein {ECO:0000269|PubMed:12486168}. Golgi apparatus membrane {ECO:0000269|PubMed:12486168}; Multi-pass membrane protein {ECO:0000269|PubMed:12486168}. Note=Localizes to the cell membrane, where it is efficiently incorporated into budding gammaretrovirus virions and impairs subsequent virion penetration of susceptible target cells (By similarity). {ECO:0000250|UniProtKB:Q86VE9}.
Interaction partners:
- Mismatch repair endonuclease PMS2
Sequence:
MGAVLGVFSLASWVPCLCSGASCLLCSCCPISKNSTVTRLIYAFILFLGTIVSCIMMTEGIQTQLKKIPGFCEGGFQIKMVDTKAEKDCDVLVGFKAVYRINFAVAIFFFAFFLLMLKVKTSKDPRAAVHNGFWFFKIAAIIGIMIGSFYIPGGSFTEVWFVAGMLGASFFIIIQLVLLVDMAHSWNELWVNRMEEGNPRLWYAALLSFTSLFYILSIVFAALLYVFYTKPDDCTENKVFISLNLIFCVAVSIVSILPKVQEHQPRSGLLQSSIITLYTLYLTWSAMTNEPERSCNPSLMSIITHLTSPTVSPANSTTLAPAYAPPSQSGHFMNLDDIWGLIIFVFCLIYSSFRTSSNSQVNKLTLSGSDSVILGDTTNGANDEEDGQPRRAVDNEKEGVQYSYSFFHLMLCCASLYIMMTITSWYSPDAKFQKVSSKWLAVWFKMGSSWLCLLLYLWTLVAPLVLTGRDFS
Protein: Epsilon tubulin (Q9NI44)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MPREVVTVQVGQCGNQLGLKWWDVLLQEHKANPQFTDARDALFDVSGSAPLASVGDKACRAGSLKARCVAVDMEEGVLRAMLRGPLGHLFDATFFVSDVSGAGNNWAVGHMEYGDKYIDSITETVREQVERCDSIQSFLIMHSLSGGTGAGLGTRVLGMLEDEFPHVFRICPVVMPSAIDDVVTAPYNTAFAVRELIEHADAVLPLDNDALARMADSALGQKTIGQAAGERKEPQTTLGAPAARGYSVAQPTQTKLPYDSMNALVAQLLSNLTCAMRFPGPLNMDINEITTNLVPYPRLLFLTSAIAPLSVARHAAASAPRSVDTMIAACLDKNHQFVDVSNGLSSALTHEAGTCLATAIVARGPQITVGDLTRNIPRIRERQKLVYWNEDGCKTALCSVSPLGHRNSVLMLANHCSIAQKLQSAHERFMRLYSVRSHVHHYEPYLEQAYFDDTCDTVLTVVDDYNYLNTVQMPADVPRSMRDLVYF
Protein: Uncharacterized protein (Q586C0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNRDKGKFPQLPPVLVQCNELESYLRTLNDQLAERLGCLWRNVAEMQGVVRTLDIHVKLIRTFLREHAVLTLSDKLFEDELVFDGGDAVDSFLPEFLRKRFNESATETELSRSSVTDESEQSNDIRERFGRINRICKDRFIRQKERNEEEHRLQTERMDACRRVEAMCRALEASQTTHMDKLERVSYWLYPIPEYENFYSENASGEGGDELLRDVRGQTKGARVVQELHETIRNAPIFLEFRRLLLRDVSERLAGALDQHSMDIANSNIASVCDCEGFRKGKRKNAGAVGSVDDGSISNPPDSASLAEQRLRVRNNGYIHISEVEALLNARVEATPVLNKGNDTNAKLIERRLLERIENLEERMAMYEAERKEFRKILSAVVDAHRSRHGIGMSLREAVLSSRSTRKGEHQDGHSNFTLYEISDPRRFAAKGTPPGSKTQASSSGRIIGSSPSPRGDKKAIVEPLNPLVVSGEASYRTVDTSTVTRETSTQEDINMTANQAAYLSYVMGKKGCRDVENLPPLPYDRKTFK
Protein: Metacaspase-4 (AtMC4) (EC 3.4.22.-) (Metacaspase 2d) (AtMCP2d) (Metacaspase-7) [Cleaved into: Metacaspase-4 subunit p20; Metacaspase-4 subunit p10] (O64517)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Plays a positive regulatory role in biotic and abiotic stress-induced programmed cell death.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:21395887}.
Interaction partners:
- Precursor of elicitor peptide 1
- Peroxidase 20
- Serpin-ZX
- Peroxidase 10
- Elicitor peptide 6
- Elicitor peptide 3
Sequence:
MTKKAVLIGINYPGTKAELRGCVNDVRRMYKCLVERYGFSEENITVLIDTDESSTQPTGKNIRRALADLVESADSGDVLVVHYSGHGTRLPAETGEDDDTGFDECIVPCDMNLITDDDFRDLVDKVPPGCRMTIISDSCHSGGLIDEAKEQIGESTKKEAEDEDESEESSSRFGFRKFLRSKVEGAIESRGFHIGGNKKDEDEAEEIETKEIELEDGETIHAKDKSLPLQTLIDILKQQTGNDNIEVGKIRPSLFDAFGDDSSPKVKKFMKVILGKLQAGNGEEGGLMGMLGKLASGFLEGKLNDEDYVKPAMQTHVGSKEEVYAGGSRGSVPLPDSGILISGCQTDQTSADATPAGKPTEAYGAMSNSIQTILEETDGEISNREMVTRARKALKKQGFTQQPGLYCHDGYANAPFIC
Protein: ABC transporter B family member 25 (ABC transporter ABCB.25) (OsABCB25) (Protein ALS1 homolog) (Protein ALUMINUM SENSITIVE 1) (OsALS1) (Q9FNU2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Metal transporter involved in the sequestration of aluminum into vacuoles, which is required for cellular detoxification of aluminum.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:22035218}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Os06g0128300 protein.
Sequence:
MGKNLRIKTGNRAPLLAQGETSRALSDLEEGSNVQPENVGFCRVIKLARHDAGKLVIATMALLVASLSNILVPKYGGKIIDIVSRDVRRPEDKAQALDDVTGTILYIVIIVVTGSVCTALRAWLFNSASERVVARLRKDLFSHLVNQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNITTTSIGLGFMFATSWKLTLLALVIVPVISIAVRKFGRFLRELSHQTQAAAAVASSIAEESFGAIRTVRSFAQESHEVLRYGEKVDETLKLGLKQAKVVGMFSGGLNAASTLSVVIVVIYGANLTINGYMTTGSLTSFILYSLTVGSSVSALSGLYTTVMKASGASRRVFQLLDRVSSMANSGDRCPTNENDGEVELDDVWFAYPSRPSHMILKGITLKLTPGSKVALVGPSGGGKTTIANLIERFYDPLKGRILLNGVPLPEISHQFLHRKVSIVSQEPVLFNCSIEENIAYGLEGKASSADVENAAKMANAHNFICSFPDQYKTVVGERGIRLSGGQKQRVAIARALLMNPRVLLLDEATSALDAESEYLVQDAMDSLMKGRTVLVIAHRLSTVKSADTVAVISDGQIVESGTHDELLSRDGIYTALVKRQLQGPRFEGTSNATAEIEPISNGQ
Protein: COP9 signalosome complex subunit 6 (Signalosome subunit 6) (Q54C92)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:16781008}.
Interaction partners:
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 2
- COP9 signalosome complex subunit 8
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 7
- COP9 signalosome complex subunit 1
- Cullin-4
- Ubiquitin-like protein NEDD8
- DNA damage-binding protein 1
Sequence:
MTDTTTTTTTDANKLVLEKSANSSGLEVDLHPLVLINISDHFTRTKVQSNYQDNCRVIGVILGVQNGRNVEICNSFEMVYATVDKQLVLDIEYLRKKYEQLFPLYDLLGWYSTGSQVSKDDILLHKQISEHNESPLYLMLDTDSPKSKDLPVIIYESELHIVNDEPTTIFVKTPYKIQTGEAERIGVNHIAKVTPSGSEGSGLTSHLFTMHNAISMLNIRVKALSDYLQAVKEKRLPYEQNILRKASSLCNQLPTIDTHDFKKSYLQEYNDVLLVTYLASITKTSASLNDTIDKYLVSNEKQSKRRFYQ
Protein: Paraxanthine methyltransferase 1 (EC 2.1.1.-) (SABATH methyltransferase PXMT1) (Q9C9M3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Methyltransferase that may methylate 1,7-paraxanthine. Prevents seed germination and modulates root architecture during early seedlings development. Plays a minor role in defense responses toward pathogenic bacteria (e.g. P.syringae).
Interaction partners:
- Calcium-binding site protein
Sequence:
MTTTPDWIMIGGDGPESYNQQSSYQRALLEATKDKMTKAISANLDLDLISNRFIVADFGCASGPNTFVAVQNIIDAVEEKYRRETGQNPADNIEFQVLFNDFSLNDFNTLFQTLPPGRRYFSAGVPGSFFERVLPKESFHIGVMSYAFHFTSKIPKGIMDRDSPLWNKDMQCTGFNPAVKKAYLDQYSIDTKILLDARAEELVPGGLMLLLGSCLRDGVKMSETPKGTVMDFIGESLSDLAKQGVTEQEKVDTFRTSIYFAEQGEIRQIIEENGKFTIEAFEDIIHAKNEFPFDPKTLAISFKAFYGAFISAHFGVEVMRKAFELVEVKAREQISRLHNSKPGMQYLIVLRKN
Protein: Basic endochitinase A (EC 3.2.1.14) (Rye seed chitinase-a) (RSC-a) (Q9FRV1)
Organism: Secale cereale (Rye)
Function: Defense against chitin-containing fungal pathogens. Binds the hyphal tips, lateral walls and septa of fungi and degrades mature chitin.
Interaction partners:
Sequence:
MGAFALFAVLAMAVTMAVAEQCGSQAGGATCPNCLCCSRFGWCGSTSDYCGDGCQSQCAGCGGGGTPVTPTPTPSGGGGVSSIVSRALFDRMLLHRNDGACQAKGFYTYDAFVAAAGAFPGFGTTGSTDTRKREVAAFLAQTSHETTGGWATAPDGAFAWGYCFKQERGATSNYCTPSAQWPCAPGKSYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTAMWFWMTAQAPKPSSHAVITGQWSPSGTDRAAGRVPGFGVITNIVNGGIECGHGQDSRVADRIGFYKRYCDILRVGYGNNLDCYNQRPFA
Protein: Centrosomal protein 20 (I3L269)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATVAELKAESGQPVVPLDRQFLIHELNAFEESKDNTIPLLYGILAHFLRGTKDGIQNAFLKGPSLQPSDPSLGRQPSRRKPMDDHLRKEEQKSTNIEDLHVSQAVNR
Protein: Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) (Q9CZR8)
Organism: Mus musculus (Mouse)
Function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03135}.
Interaction partners:
- Elongation factor Tu, mitochondrial
- Ribosome-recycling factor, mitochondrial
- Protein RRP5 homolog
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL9m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS3
Sequence:
MSLLRSLRFFPVACTGRSARAVLLQPSQPWLTFHAGPSLSSAASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQAEDWLHKQAQKEGWSKAAKLHGRKTKEGLIGLLQEGNTAVLVEVNCETDFVSRNLKFQQLVQQVALGTMAHCQNLTDRLSTYSKGFLNSSELSELAAGPDREGSLKDQLALAIGKLGENMILKRAAWVKVPSGFYVGSYVHGVTQSPSLQNLVLGKYGALVICETPEQIANLEEVGRRLGQHVVGMAPLSVGSLDDEPGGETETRMLPQPYLLDPSITLGQYVQPQGVTVVDFVRFECGEDEQVAEAE
Protein: Uncharacterized protein (Q38FV1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSRQTRRMGISLDASNVYEMDPWKDDRCRDFIALNTIQRLRSYHANTTLPVEPINAARAKNLHLLLAAEPDERICTSEDGCAVDMARIIFFGPMAFVSKTSAGRMTASPHITSHSGSRGDTDNVEETSRASLLVVSKDEENGGGRVSSSSDGNKRLREQSDAFEAGATPLKRVITEGNGGTPSPQLPERSLPVAVGQGGGASSDRKTSRQVSGKSDVVKFSCAIVDTIVSYYQSLLTRGVVLDRFSSKDLAFSWWVVCRNMDVEVLKNHVGPTRRDTLLISLRHFYYELLSNFHPKKSVPQEPSNTLSVAAKQKVEETDEGGGEEDKLPNTQATRKRAPPQRKAEATENNVAEEEEENDEEKPRLRTRFDSTRNGPPPPGTRSRHRGHRPKESSTGGEVSEVRSATKPTGSGPNKTWEASGHTRSSAKLATGTKEKATEVVKATVESRTIARSSRVSAPAAAAESNEKKDPPVSDVAEAPDAAKRLRPPRSACLAEIWRSIRPTRRRSAQVGGTIDSVQDGVATGGLKPPNYVASCSAVVERIHERMEDDPVYAALFTAFPQNNKNSTKVEDGSQNHDTKETESEVEHGMHPSLIQLLRYYHTGSSTPSIPLVKFDEENVKNEARQQTRPSTNEEELEGQQAGPSVLCTNGVEKVTTDVEKTGRSDVCNPESSSPLMHQSCPFSALTYAQRCLLTWEASLLLDTQQPQPARKRQAAASGQTHNAVPLEPSPRRNYYDYWTCQRMPKPS
Protein: Protein lin-11 (Abnormal cell lineage protein 11) (P20154)
Organism: Caenorhabditis elegans
Function: Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons.
Subcellular location: Nucleus.
Interaction partners:
- Cyclin-like domain-containing protein
- Serine protease inhibitor 1 protein
- Paired box protein 5 homolog
- 63 kDa sperm flagellar membrane protein
- Transcription factor unc-86
- COG-1A
- DUF4704 domain-containing protein
Sequence:
MHSSSSFIITSLEEEEKKPPAHHLHQQSIEDVGSVTSSATLLLLDSATWMMPSSTTQPHISEISGNECAACAQPILDRYVFTVLGKCWHQSCLRCCDCRAPMSMTCFSRDGLILCKTDFSRRYSQRCAGCDGKLEKEDLVRRARDKVFHIRCFQCSVCQRLLDTGDQLYIMEGNRFVCQSDFQTATKTSTPTSIHRPVSNGSECNSDVEEDNVDACDEVGLDDGEGDCGKDNSDDSNSAKRRGPRTTIKAKQLETLKNAFAATPKPTRHIREQLAAETGLNMRVIQVWFQNRRSKERRMKQLRFGGYRQSRRPRRDDIVDMFPNDQQFYPPPPPSNVQFFCDPYTTSPNNPETIQMAPQFAVPTENMNMVPEPYTEQSATPPEFNEDTFACIYSTDLGKPTPVSW
Protein: UDP-glycosyltransferase 75B2 (EC 2.4.1.-) ((Uridine 5'-diphosphate-glucose:indol-3-ylacetyl)-beta-D-glucosyl transferase 2) (IAA-Glu synthase 2) (Indole-3-acetate beta-glucosyltransferase 2) (EC 2.4.1.121) (Q9ZVY5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses low catalytic activity in vitro. Also active as glucosyltransferase in vitro on benzoates and benzoate derivatives.
Interaction partners:
Sequence:
MAQPHFLLVTFPAQGHVNPSLRFARRLIKTTGARVTFATCLSVIHRSMIPNHNNVENLSFLTFSDGFDDGVISNTDDVQNRLVHFERNGDKALSDFIEANQNGDSPVSCLIYTILPNWVPKVARRFHLPSVHLWIQPAFAFDIYYNYSTGNNSVFEFPNLPSLEIRDLPSFLSPSNTNKAAQAVYQELMDFLKEESNPKILVNTFDSLEPEFLTAIPNIEMVAVGPLLPAEIFTGSESGKDLSRDHQSSSYTLWLDSKTESSVIYVSFGTMVELSKKQIEELARALIEGGRPFLWVITDKLNREAKIEGEEETEIEKIAGFRHELEEVGMIVSWCSQIEVLRHRAIGCFLTHCGWSSSLESLVLGVPVVAFPMWSDQPANAKLLEEIWKTGVRVRENSEGLVERGEIMRCLEAVMEAKSVELRENAEKWKRLATEAGREGGSSDKNVEAFVKSLF
Protein: ATPase MORC2B (EC 3.6.1.-) (MORC family CW-type zinc finger protein 2B) (TCE6) (Q8C5W4)
Organism: Mus musculus (Mouse)
Function: Required for chromosomal synapsis and meiotic recombination in males and females.
Subcellular location: Nucleus {ECO:0000269|PubMed:29329290}.
Interaction partners:
- Zinc finger protein 870
Sequence:
MAFTNYSTLNRAQLTFDYLHTNSTTHAFLFGALAELIDNARDADATRIDIYAEKREDLQGGFMLCFLDNGVGMDPNDVINVIQFGKSAKRTPESTQIGRYGNGLKSGSMRIGKDFILFTKKENTMSCLFLSRTFHEEEGIDEVIVPLPTWNSQTREPVTDNMEKFAIETELIYKYSPFHTEEEVMTQFTKISGTSGTLVVIFNLKLTDNGEPELDVTSNPKDIRMAEISQEGVKPERHSFCAYAAVLYIDPRMRIFIHGHKVQTKKLCCCLYKPRKYTFTSHRFKTRAEQEVKKADQVAQLAEEKAREAESKARTLEIHMGGDITRDSRVMLRQVQNTAITLRREADVKKRIRDAKQQALKEPKELTFVFGVNIEHRDHDGMFIYNCSRLIKMYEKVGPQLEKGMVCGGVVGVIDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIEIAQHGIIKFWDEFGYLSANWNRPPSDELHFKRKRAMQVPTTIQCDLCLKWRTLPFQLSAVEEGYPINWVCSMNPDPEQDQCEAFELKQKIPLGILKKAPKTQEERQKQLTEKIQQEQRKLKALKKIKPIHSQSDLKKLPLEVTSRPFSKYPAHIFQGPQSSFHVVKTNARRRPQSRHAPFRQLQRSSIICTNPKPPFLVDKTEAVLLQPPETPQKSVSLLVKTIPQPPPLVQSLSPSVVPKSNNPWKVETPQIMNTPVAEMPYVPVNPSLVICDHKRSPEVSDEIEDEDRRKRMCKRGRFTVKKEKIQASELSDSSGEENPVDLKTAQKDKGLYVEVRMMGECYKGHVTAVEVGDNVVWWKVKFEDMPKDSTPRDCWVEKGSENVWLVKPSPEYQSTDEQQEDRKGEEDTVVQQALALQQTSTSECFCTEPDTTASTANHKTIDLLVQILWNCLHYFMPLSFPISKKELGAMNSEELLSLPLKECFKQYEVGLQNLCRSYQRCADSQAKVSEESLRISQKKLQETEEKLQKLRTNIQTLLQMAQQGINIRADDELDAYIEDLVSSDD
Protein: Large ribosomal subunit protein eL19 (22 kDa calmodulin-binding protein) (60S ribosomal protein L19) (Vegetative-specific protein V14) (P14329)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Ribosomal protein that binds calmodulin.
Interaction partners:
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL18
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein eL13
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein eL36
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein eS19
- Large ribosomal subunit protein eL34
Sequence:
MVSLKLQKRLAASILKCGKGRVWIDPNEIADVAMANSRDNVRRLIATGFIMRKPVVVHSRSRAREHNAAKRLGRHRGAGNRLGTREARLPSKILWIRRIRVLRRLLKKYREAKKIDKHSYRELYLKAKGNVFKNKRTLIEYIVKSKTEKLREKLIQDQAQARRNKNKSIKDRRAAKSAAKEIVSSN