wanglab/gogpt-training-data huggingface dataset:
Protein: Aquaporin-1 (B5X1X5)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Aquaporin
- Aquaporin
- Aquaporin
Sequence:
MGELRNWAFWRAVLAELIGMILFIFIGISSAIGNTNNSQPDQEVKVALAFGLAIATLAQSLGHISGAHLNPAITLGLLVSCQISVFKAVFYILAQMLGAVVASAIVYGVKPTNIDALGVNHLNKISVGQGFVIELLTTFQLVLCVIAVTDKRRGDVTGSAPLAIGLSVGLGHLAAISFTGCGINPARSFGPAVIYKQFGDHWVYWLGPMCGGVAAALIYDFLLYPRSDDFSKRRNVLVSGPDKENDAPEEGSSSPGTSQWPR
Protein: Small ribosomal subunit protein eS1 (40S ribosomal protein S3a) (Protein TU-11) (P97351)
Organism: Mus musculus (Mouse)
Function: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03122, ECO:0000269|PubMed:10713066, ECO:0000269|PubMed:36517592}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03122, ECO:0000269|PubMed:10713066}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P61247}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000255|HAMAP-Rule:MF_03122}.
Interaction partners:
- Large ribosomal subunit protein eL8
- Small ribosomal subunit protein eS17
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein RACK1
- Ubiquitin-like protein FUBI
- Small ribosomal subunit protein eS8
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein uL15
Sequence:
MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSSGKAAGDETGAKVERADGYEPPVQESV
Protein: phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (Q84TI2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic
- Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial
- Phosphoribosylamine--glycine ligase, chloroplastic
- Adenylosuccinate lyase
- Adenylosuccinate lyase
- AICARFT/IMPCHase bienzyme family protein
- Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic
- Amidophosphoribosyltransferase 1, chloroplastic
- Phosphoribosylglycinamide formyltransferase, chloroplastic
- Amidophosphoribosyltransferase 3, chloroplastic
Sequence:
MLLLKQSSAAVLVVGNTTPVLHTSRSTYRVGPFPVTRTQSFQSLTMANLQKLPTSSSGKLNTASAVPCSSHDASPISENRENKHVHGVSEKIVGVLGGGQLGRMLCQAASQLAIKVMILDPSKNCSASALSYGHMVDSFDDSATVEEFAKRCGVLTVEIEHVDVDTLEKLEKQGVDCQPKASTIRIIQDKYMQKVHFSQHGIPLPEFMEISDIEGARKAGELFGYPLMIKSKRLAYDGRGNAVANNQDELSSAVTALGGFSRGLYIEKWAPFVKELAVIVARGRDGSMVCYPVVETIHRDNICHIVKAPADVPWKINKLATDVAQKAVGSLEGAGVFAVELFLTEDSQILLNEVAPRPHNSGHQTIECCYTSQFEQHLRAVVGLPLGDPSMRTPASIMYNILGEDDGEAGFKLAHRLIARALCIPGASVHWYDKPEMRKQRKMGHITLVGQSMGILEQRLQCILSEQSHQVHETPRVAIIMGSDTDLPVMKDAAKILDLFGVTHEVKIVSAHRTPEMMYTYATSAHSRGVQVIIAGAGGAAHLPGMVASLTPLPVIGVPVRATRLDGVDSLLSIVQMPRGVPVATVAINNATNAALLAVRMLGISDTDLVSRMRQYQEDMRDENLNKGEKLETEGWESYLNQ
Protein: Alanine aminotransferase 2, mitochondrial (AtAlaAT2) (AtAlaATm) (EC 2.6.1.2) (Alanine-2-oxoglutarate aminotransferase 3) (EC 2.6.1.-) (Q9LDV4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305|PubMed:25732537}.
Interaction partners:
- Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial
- Serine--glyoxylate aminotransferase
- Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial
- NAD-dependent malic enzyme 2, mitochondrial
- Arginine biosynthesis bifunctional protein ArgJ
- Aspartate aminotransferase, chloroplastic
- Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial
- Aspartate aminotransferase, mitochondrial
- Pyruvate, phosphate dikinase 1, chloroplastic
- glutamate dehydrogenase
Sequence:
MRRFLINQAKGLVDHSRRQHHHKSPSFLSPQPRPLASSPPALSRFFSSTSEMSASDSTSSLPVTLDSINPKVLKCEYAVRGEIVNIAQKLQEDLKTNKDAYPFDEIIYCNIGNPQSLGQLPIKFFREVLALCDHASLLDESETHGLFSTDSIDRAWRILDHIPGRATGAYSHSQGIKGLRDVIAAGIEARDGFPADPNDIFLTDGASPAVHMMMQLLLSSEKDGILSPIPQYPLYSASIALHGGSLVPYYLDEATGWGLEISDLKKQLEEARSKGISVRALVVINPGNPTGQVLAEENQRDIVNFCKQEGLVLLADEVYQENVYVPDKKFHSFKKVARSLGYGEKDISLVSFQSVSKGYYGECGKRGGYMEVTGFTSDVREQIYKMASVNLCSNISGQILASLVMSPPKPGDDSYDSYMAERDGILSSMAKRAKTLEDALNSLEGVTCNRAEGAMYLFPRINLPQKAIEAAEAEKTAPDAFYCKRLLNATGVVVVPGSGFGQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEFRN
Protein: Phosphatidylglycerol lysyltransferase (EC 2.3.2.3) (Lysylphosphatidylglycerol synthase) (Q9I537)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Bacterial virulence domain-containing protein
Sequence:
MRTDAPVPEHPAPPSSPASPQRIRLIDRITAYRQPIGLVFTLLLFGLALVACYHLLREIDPGALHDAIADVPRPALLGALSATALGFVILLGYEWSASRFAGVTLPMRSLATGGFSAFAIGNAVGLSLLSGGSVRYRLYSRHGIGAAEIARMTLFASLSLGCALPVLAALAALCDLDDAASALHLPRALVAVIAIAVLSLAVGLVAFLARHRLPGERPSPDSLLVRLGRRSLRLPGLRLSLLQLLITALDVAAAATVLYLLLPETPPFAAFLLVYLLALAAGVLSHVPGGVGVFEAVLLAAFAGQLGAAPLAAALLLYRLIYVVLPLLLACLLLLFLEARRLWVTRQAIRVASGFAAPILAILVFLSGVVLLFSGATPAIDTRLEHLGFLIPHRLIDASHLVASLIGVLCLLLAQGLRRRLSAAWALTLVLLLVGALLSLLKGFDWEEASLLSLTAALLAMFRRSFYRPSRLMEVPFSPLYVGASICVVGASVWLLLFANQDVHYSNQLWWQFALDADAPRALRAALGSCLLLLALALGWLLRAAPPAIREPNAEELQRAARIIRHSDQPDGGLALTGDKALLFHESDDAFLMYARRGRSMIALYDPIGPAMQRAELIWQFRDLCDLHHARPVFYQVRAENLPFYMDIGLTALKLGEEARVDLLRFDLENKGKEMKDLRYTWNRGQRDGLALEFHEPGQAPLDELKAISDAWLGGKQVREKGFSLGRFTPAYLNFFRIAIVRHQGKPVAFANLLETDSRELASLDLMRVHPDAPKLTMEFLMLGLILHYKAQGHARFSLGMVPLAGLQPRRGAPLTQRLGALVFRRGEQFYNFQGLRRFKDKFQPDWEPRYLAVPAGLDPLVALADTAALIAGGLTGLVKR
Protein: NMDA receptor 2, isoform C (NMDA receptor subunit 2-2) (Q9W581)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}.
Interaction partners:
- Glutamate [NMDA] receptor subunit 1
- Disks large 1 tumor suppressor protein
- Calcium/calmodulin-dependent protein kinase type II alpha chain
- Peripheral plasma membrane protein CASK
- Glutamate receptor IB, isoform B
- Glutamate receptor 1
- Glutamate receptor IIA
- Metabotropic glutamate receptor
- AT10229p
- Glutamate receptor IIB
Sequence:
MMPSRVKLKRGTDGPTPTPTPMPTTMRKHTPIATLNTASCQHNSTTSRRKRILTPPSGPISLLLLTVLTLLILDTRSCQGLRLTNGGGSLSKGAAANKEQLNIGLIAPHTNFGKREYLRSINNAVTGLTKTRGAKLTFLKDYSFEQKNIHFDMMSLTPSPTAILSTLCKEFLRVNVSAILYMMNNEQFGHSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDLMELVNSEARVMLLYATQTEAITILRAAEEMKLTGENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLEKVMDKHGIKAPQLRLASSSDLLNHHHLKERPPLLGNLSLAASAQDLYRWSYKTEIAEMETVL
Protein: KH-type splicing regulatory protein (M0R0C6)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQASGNCHPPPPPFSFQPPATVHPALVGSAGNPFPCGVCP
Protein: Intestinal-type alkaline phosphatase 1 (IAP-1) (Intestinal alkaline phosphatase 1) (EC 3.1.3.1) (Intestinal alkaline phosphatase I) (IAP-I) (P15693)
Organism: Rattus norvegicus (Rat)
Function: Alkaline phosphatase that can hydrolyze various phosphate compounds.
Subcellular location: Cell membrane {ECO:0000269|PubMed:2155025}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:2155025}.
Interaction partners:
- Thiamine pyrophosphokinase
- GTP cyclohydrolase 1
- 6-pyruvoyl tetrahydrobiopterin synthase
- Nucleoside-triphosphatase, cancer-related
- Glutathione hydrolase 6
- Glutathione hydrolase 7
- Aspartate aminotransferase, cytoplasmic
Sequence:
MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
Protein: Protein SNA4 (Q07549)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:11566881, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16107716}; Multi-pass membrane protein {ECO:0000269|PubMed:11566881, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16107716}.
Interaction partners:
- Plasma membrane proteolipid 3
- Uncharacterized protein ANR2
Sequence:
MCCYCVCCTVSDFILYIVAFFFPPAAVLLRSGPCSSDFLLNVLLTLLGFLPGMLHAFYYITITSPLRNAEYVYYYQQGWVDSERNVPSNRPQNSQTPQNRPQQGSSARNVYPSVETPLLQGAAPHDNKQSLVESPPPYVP
Protein: Two-component response regulator ORR9 (Type A response regulator 9) (OsRR9) (Q4GZK2)
Organism: Oryza sativa subsp. indica (Rice)
Function: Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
Interaction partners:
Sequence:
MAVAIEAPFHVLAVDDSLPDRKLIERLLKTSSFQVTTVDSGSKALEFLGLHDHEDSPISTQSDQQEVAVNLIITDYCMPGMTGYDLLKKIKESSYLRDIPVVIMSSDNIPSRINRCLEEGADEFFLKPVRLSDMSKLKPHILKSRCKEHYQQEQNLQSNSESNNSSNPTSENSSSSTSSNSHKRKAVDEEILPHTIRPRHS
Protein: General transcription factor IIF subunit 2 (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (P41900)
Organism: Drosophila melanogaster (Fruit fly)
Function: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.
Subcellular location: Nucleus.
Interaction partners:
- General transcription factor IIF subunit 1
- Transcription initiation factor IIB
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB3
- Transcription initiation factor IIE subunit beta
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerase II subunit RPB7
- General transcription factor IIE subunit 1
Sequence:
MSKEDKEKTQIIDKDLDLSNAGRGVWLVKVPKYIAQKWEKAPTNMDVGKLRINKTPGQKAQVSLSLTPAVLALDPEEKIPTEHILDVSQVTKQTLGVFSHMAPSDGKENSTTSAAQPDNEKLYMEGRIVQKLECRPIADNCYMKLKLESIRKASEPQRRVQPIDKIVQNFKPVKDHAHNIEYRERKKAEGKKARDDKNAVMDMLFHAFEKHQYYNIKDLVKITNQPISYLKEILKDVCDYNMKNPHKNMWELKKEYRHYKTEEKKEEEHKSGSSDSE
Protein: Toll-like receptor 2 (Q2XQ10)
Organism: Gallus gallus (Chicken)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MRILIGSLYFYFISFLFSKVNGFLTQRTSPVSSFPFYNYSYLNLSSVSQAQAPKTARALNFSYNAIEKITKRDFEGFHVLEVLDLSHNHIKDIEPGAFENLLSLVSVDLSFNDKNLLVSGLAPHLKLIPTSGASGPSQIYMYFQKSAEAALEPSAPAELLPHLEDPPNPGNVNPRFRQRRTEENKTSPPAATLRPDLCGAPINGLLDLSRTKLSNEELTAKLDADLCQAQLGTVLEFNISHSDLEMDLLSLFILFLPMKDIQSVDASYNRITINNIDVEAICHFPFSNFSFLNISNNPINSLETVCLPASITVIDLSFTNISTIPANFAKKLSKLERMYVQGNQLIYTVRPENPSATPRPPPGTVQISAISLVRNQAGTPIESLPESVKHLKVSNCSIVELPEWFANRMQELLFLDLSSNRISMLPDLPISLQQLDISNSDIKIIPPRFKSLSNVTVFNIQNNKLTEMHPEYFPSTLTTCDISKNKLKVLSLTKALENLESLNVSGNLITRLEPACQLPSLTNLDSSHNLISELPDHLGQSLLMLKHFNLSGNKISFLQRGSLPASLEELDISDNAITTIVQDTFGQLTSLSVLTVQGKHFFCNCDLYWFVNIYIRNPHLQINGKDDLRCSFPPDRRGSLVKSSNLTLLHCSLGIQMAITACMAILVVLVLTGLCWRFDGLWYVRMGWYWCMAKRRQYKKRPENKPFDAFISYSEHDADWTKEHLLKKLETDGFKICYHERDFKPGHPVLGNIFYCIENSHKVLFVLSPSFVNSCWCQYELYFAEHRVLDENQDSLIMVVLEDLPPDSVPQKFSKLRKLLKRKTYLKWSPEEHKQKIFWHQLAAVLKTTNEPLVRAENGPNEDVIEME
Protein: DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (P62488)
Organism: Mus musculus (Mouse)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA. Binds RNA (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P62487}.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
Sequence:
MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS
Protein: GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (G4SNP0)
Organism: Caenorhabditis elegans
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367138}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367138}.
Interaction partners:
- GPI mannosyltransferase pigv-1
- Mannosyltransferase
- DNL-type domain-containing protein
- Uncharacterized protein tag-51
- Putative ATP-dependent DNA helicase Q1
- Actin-related protein 2/3 complex subunit 5
- Glycosyltransferase 2-like domain-containing protein
- Exoribonuclease phosphorolytic domain-containing protein
- Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein
- Probable actin-related protein 2/3 complex subunit 2
Sequence:
MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKFAATVNCSMDLLDLNPTFCDCSVVAHGSISCGSSNCIRLMLLCEKIVPYSLLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAFEFRKFPGKRNHQEIESISSRKLSDDESA
Protein: Ras-related protein RABB1b (AtRABB1b) (Ras-related protein GB2) (AtGB2) (Ras-related protein Rab2C) (AtRab2C) (Q38922)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Intracellular vesicle trafficking and protein transport.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Kinesin-like protein KIN-14E
- Rho GDP-dissociation inhibitor 1
- Probable inactive poly [ADP-ribose] polymerase SRO5
- Succinate dehydrogenase subunit 8
- At1g12070
- Succinate dehydrogenase subunit 7A
- Pentatricopeptide repeat-containing protein At4g35850
- Succinate dehydrogenase subunit 7B
- Immunoglobulin E-set superfamily protein
- GTP binding protein-like
Sequence:
MSYDYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTVDGRPIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLASWLEDARQHANPNMSIMLIGNKCDLAHKRAVSKEEGQQFAKEHGLLFLEASARTAQNVEEAFIETAAKILQNIQDGVFDVSNESSGIKIGYGRTQGAAGGRDGTISQGGGCCG
Protein: Polymerase cofactor VP35 (Ebola VP35) (eVP35) (Q05127)
Organism: Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus)
Function: Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes (By similarity). Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1. VP35-NP interaction controls the switch between RNA-bound NP and free NP and thus the switch between genome replication and genome packaging into the nucleocapsid. Prevents establishment of cellular antiviral state, thereby suppressing host DC maturation. Acts by inhibiting host RIGI activation both by shielding dsRNA from detection and by preventing PRKRA binding to RIGI. Blocks virus-induced phosphorylation and activation of interferon regulatory factor 3/IRF3, a transcription factor critical for the induction of interferons alpha and beta. This blockage is produced through the interaction with and inhibition of host IKBKE and TBK1, producing a strong inhibition of the phosphorylation and activation of IRF3. Also inhibits the antiviral effect mediated by the host interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR. Increases PIAS1-mediated SUMOylation of IRF7, thereby repressing interferon transcription. Also acts as a suppressor of RNA silencing by interacting with host DICER1, TARBP2/TRBP and PRKRA/PACT (By similarity). As a dimer, binds and sequesters dsRNA contributing to the inhibition of interferon production (By similarity).
Subcellular location: Virion. Host cytoplasm {ECO:0000269|PubMed:23493393, ECO:0000269|PubMed:28679761}.
Interaction partners:
Sequence:
MTTRTKGRGHTAATTQNDRMPGPELSGWISEQLMTGRIPVSDIFCDIENNPGLCYASQMQQTKPNPKTRNSQTQTDPICNHSFEEVVQTLASLATVVQQQTIASESLEQRITSLENGLKPVYDMAKTISSLNRVCAEMVAKYDLLVMTTGRATATAAATEAYWAEHGQPPPGPSLYEESAIRGKIESRDETVPQSVREAFNNLNSTTSLTEENFGKPDISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASLAEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPSPKIDRGWVCVFQLQDGKTLGLKI
Protein: Tryptamine benzoyltransferase 2 (OsTBT2) (EC 2.3.1.-) (Q2R0J4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from benzoyl-CoA to tryptamine, to produce benzoyl tryptamine. Serotonin and tyramine serve as acyl acceptors in vitro. Specific for benzoyl-CoA as acyl donor. Has no activity with p-coumaroyl-CoA, caffeoyl-CoA, or feruloyl-CoA as acyl donors.
Interaction partners:
- Nitrate reductase 1
- Nitrate reductase
- Nitrate reductase
- Probable 5'-adenylylsulfate reductase 1, chloroplastic
- 4-coumarate--CoA ligase
Sequence:
MEITSSAMLKPAPTPTPHPLAGEKVPLTAFDRAAFDVFVPMVFAYRAPAPSSEAVKEGLRMAVAAYPLAAGRLAVDVAADGQGRRRRRRVLHVNDEGALVLDATVEADLDAVLAANVATDLYPAPPEHSFGAAVLQVQLTRFRCSGLVVGLIVHHHVFDGHSTSAFCTTWARAVRDGEAFSVPSPCLDRAITSVPRSPPAPVFDHRSIEFKVGNKSSDSSGAAAAAVEKITNIGVRFTAKFVAELKARVGGRCSTFECVLAHAWKKMTAARGLKPEEFTRVRVAVNCRRRANPPAPADLFGNMVLWAFPRLQVRRLLSASYRDVVGAIRAAVARVDGEYIQSFVDYVEVADARGEELAATAAEPGETLCPDLEVDSWLGFRFHEMDLGTGPPAAVLSPDLPIEGLMILVPVGGDGGGVDLFVALADDRAQVFEQICYSLEEHAIPSHL
Protein: Large ribosomal subunit protein bL33c (50S ribosomal protein L33, chloroplastic) (P0C455)
Organism: Oryza sativa (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
Sequence:
MAKGKDVRIRVILQCVSCVRKGANEESAGISRYSTQKNRHNTPGQLELRKFCRYCRKHTIHAEIKK
Protein: Protein OS-9 (Amplified in osteosarcoma 9) (Q13438)
Organism: Homo sapiens (Human)
Function: Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18417469, ECO:0000269|PubMed:19084021}.
Interaction partners:
- Protein sel-1 homolog 1
- Derlin-2
- E3 ubiquitin-protein ligase synoviolin
- Endoplasmin
- Protein FAM8A1
- FAS-associated factor 2
- Transitional endoplasmic reticulum ATPase
- Derlin-1
- E3 ubiquitin-protein ligase AMFR
- Derlin-3
Sequence:
MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF
Protein: CBL-interacting serine/threonine-protein kinase 19 (EC 2.7.11.1) (SNF1-related kinase 3.5) (SOS2-like protein kinase PKS21) (Q9FJ55)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
Interaction partners:
- Putative MO25-like protein At5g47540
- Putative MO25-like protein At4g17270
- At5g18940
- MO25-like protein At2g03410
Sequence:
MADLLRKVKSIKKKQDQSNHQALILGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHIKREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGDFRCPRWFPVEINRLLIRMLETKPERRFTMPDIMETSWFKKGFKHIKFYVEDDHQLCNVADDDEIESIESVSGRSSTVSEPEDFESFDGRRRGGSMPRPASLNAFDLISFSPGFDLSGLFEDDGEGSRFVSGAPVGQIISKLEEIARIVSFTVRKKDCKVSLEGSREGSMKGPLSIAAEIFELTPALVVVEVKKKGGDKMEYDEFCNKELKPKLQNLSSENGQRVSGSRSLPSFLLSDTD
Protein: Stanniocalcin (STC) (Corpuscles of Stannius protein) (Q1AFD6)
Organism: Scophthalmus maximus (Turbot) (Psetta maxima)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU369112}.
Interaction partners:
Sequence:
MLPGSSLLLLLLLGSSACFELLPEEAAPRRARFSSNSPTDVARCLNGAVAVGCGFFSCLENSTCDTDGMHEICELFLHTAATFNTEGKTFVKRSLQCISQGISSKIFQTIRRCNIFQMMIAEVQEECYSSLDICTVARTNPEAIGEVVQVPTHFPNRHYSTLLQSLQACDEPTVAAVRSGLIARLGPDMETFLQLVQNKPCAAASGSAAAYSNPSSWRNMPVFNVQPSFRGRDPTHLFARRSVDDGEK