wanglab/gogpt-training-data huggingface dataset:
Protein: Doublesex-Mab related 11E (Q9VYE0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00070}.
Interaction partners:
Sequence:
MHFDETRSPNKDVRIGKSQRLAANGRQGTDPESDPLHARCVVPHASTPRGRRIPWGHNDDDDDGNHLTLPDSLTATSSCGCQCLNVRAPFHILLVDQQARMSKDASVRICQRERRLLRTPKCARCRNHGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATASSTKSTGVTTASANNSSSSEGEDSLSSTSPPPAHSHPHSHSHPTSCVSNSSSSSATRQALMAQKRIYKQRLRSLQQSTLHITAAMEEYKQRFPTFSSPLMERMRKRRAFADPELNHVMEATLGGNALYFATVAAAAAACAPVHQEQHIYHPMPPTIPLTIPPTNPAMTTPAVTTASTGSGKKPKLSFSIESIMGIST
Protein: 5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA oxidase) (EC 1.14.18.-) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75) (Tyrosinase-related protein 1) (TRP) (TRP-1) (TRP1) (P17643)
Organism: Homo sapiens (Human)
Function: Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin (By similarity).
Subcellular location: Melanosome membrane {ECO:0000250|UniProtKB:P07147}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P07147}. Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. {ECO:0000250|UniProtKB:P07147}.
Interaction partners:
- P protein
- Membrane-associated transporter protein
- Microphthalmia-associated transcription factor
- Melanocyte-stimulating hormone receptor
- Cyclin-dependent kinase 1
- Melanocyte protein PMEL
- Melanoma antigen recognized by T-cells 1
- Sodium/potassium/calcium exchanger 5
- Tyrosinase
- G-protein coupled receptor 143
Sequence:
MSAPKLLSLGCIFFPLLLFQQARAQFPRQCATVEALRSGMCCPDLSPVSGPGTDRCGSSSGRGRCEAVTADSRPHSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGAACDQRVLIVRRNLLDLSKEEKNHFVRALDMAKRTTHPLFVIATRRSEEILGPDGNTPQFENISIYNYFVWTHYYSVKKTFLGVGQESFGEVDFSHEGPAFLTWHRYHLLRLEKDMQEMLQEPSFSLPYWNFATGKNVCDICTDDLMGSRSNFDSTLISPNSVFSQWRVVCDSLEDYDTLGTLCNSTEDGPIRRNPAGNVARPMVQRLPEPQDVAQCLEVGLFDTPPFYSNSTNSFRNTVEGYSDPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYTYEIQWPSREFSVPEIIAIAVVGALLLVALIFGTASYLIRARRSMDEANQPLLTDQYQCYAEEYEKLQNPNQSVV
Protein: Helicase POLQ-like (EC 3.6.4.12) (H2KY86)
Organism: Caenorhabditis elegans
Function: Single-stranded 3'-5' DNA helicase that plays a key role in homology-driven double-strand break (DSB) repair. Involved in different DSB repair mechanisms that are guided by annealing of extensive stretches of complementary bases at break ends, such as microhomology-mediated end-joining (MMEJ), single-strand annealing (SSA) or synthesis-dependent strand annealing (SDSA).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8TDG4}. Chromosome {ECO:0000250|UniProtKB:Q8TDG4}. Note=Localizes to sites of DNA damage. {ECO:0000250|UniProtKB:Q8TDG4}.
Interaction partners:
- RAD51-like protein 1
- Regulator of telomere elongation helicase 1 homolog
- FANCD2
- DNA repair protein RAD51 homolog
- Uncharacterized protein B0353.1
- DNA repair and recombination protein RAD54-like
- RecQ-like DNA helicase blm-1
- Crossover junction endonuclease MUS81
- ATP-dependent helicase wrn-1
- Serine/threonine-protein kinase ATM
Sequence:
MNRTPIRRCKSAEIEEDPFSPIPKFSRLRTPRTSREYVCPLKSTSPQSPSSSTENEPPPVSVTSPPARKRALEESTVTPIQQKIGPPVLKRSSLSKLADGFRTAAYLNNESENDDDPFGLSFRNEQVLMSKCAPAPEKRPETLTLDPSKCLPERDMEMYRKIKKLDKFYDWQQECLSDKRLLDGENCILSLPTGAGKTLIAEVLMLREAIVRKRNAILVLPYVAIVQEKISALAPFEDAFGINIEEYASNKGRFPPIKRRKRVSVYVATIEKANMLINSLITQGQLDRVGMVVVDELHMIGDGGRGAILEQLLAKFLYKGTGQIVGMSATLPNIDDLKFALRAFVYSTNFRPVELTEFVKIGQTMHQVSENGDLNPAGDLPTNNLKSTDPDGICQLLAKLIPKNSAVIFCPNKKNCENVAVLIAKTLPAHIRQAKRAESDAFLQSYLSDNDDERMDAVLKQCILSGVAYHHSGLTQDERKCVEAAFMEGLIYVVCATSTLAAGVNLPVRRVIIKAPMVGRERLGKAQYLQMAGRAGRAGFDTKGDCITIIKAGEEERWFREMLKSDIPRCMSSLSSEESMGSFILDCVVLKLAENIEEIMTAVRYSLFYAQESPENIRKLVESSVKRLEEHYFITIEPLEQDVASEPSAQASSIPRVPGKISPSDLGNAVFNAGFDPDEATRLHADLVSSLNQGVIFASHFHLLFIITPYEQVCNINWDLFLLMYNALPSSERKLLAECGLEEKFILEAIITRVDLTAGTPRMRLYIALMLQKIWNHEPMYTVAERFGVEKGWLQATLQSSISQAASIAKFSEKITTMWPLRKLLPELVQRLSEAAQPELLPLMTVDGIKKARAAILFKAGYKTVGMIARANPLKLVQELGTIRMAQANSIIASARMVLRDQVDEKMEELDVWGVATDSFNYF
Protein: Znc1p (A0A1D8PNA4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Uga33p
Sequence:
MSDVNDTLNPVYTQDGEKRLRTKVACDYCRKRKSKCNGEQPCSKCLDKNRNCTYTFVQKERKRTQRKPTAGAENKNNGAIRKARTTSAATIRQLTSRINVLESLLGRLVDKLDPNVKSELSEELQSSSFTNGNNDSREKHNGSSSNSSDNGDDEENDLQEAHEGDDSDDKNNSDGSIEYNHNDENSKQIDTKSSNDNEVRKLRDMLAPAEKSCVSNIKNRLMQYFGSHALFFSISGRAVEWLRSRVQGSNANNMNDIFAPLRHVPLSLNDAVQKSTKLLNGPDVETDKKRQFDDLEKSLIFEIIDKYYKDLYWAPFLCDVSTIRELFQIYFYGAQRNDAAILGNITYSDLLIMNIALVLCLANISRDDVIDSLEYPNLSTKSVSYLQSELLNKLFLNAMGAYGKVSRNSDGIRSLQGLALLILYFEINFVTDFHVNYSITSVLIRYAKESGIHRVETLNNDNGVEATLKRKLWWFCEYKGVDITYKSGKPILIDMDDVTTLTEVDDFFMSVPTTLFLNGKYLENANDIVLNSQIHGGEYYFAYFLLILSRIKAKSYAKIYSKLPTNINIQAALTFVNEFDYDLRILTNLMSPILAATTTISSPNSTTVKNPLNLSEGCFNYFKVELLLSQYAHQLSINRVPFVKSFGINDSRLIPYGNQSLAGARSMLELIKDIGSLKISQRMYSALSFYPLAAFCSLLGNCLVFPSEPSAVDNSVLLANVAISFFRSEGCNNKIDNKRSIYDILVRLLLRVLIDALKNLAKVDLYEKIPELEYHINSMFTLFPEVFANQQDQIISLMSERNSNNENANQHSNMIENGSSSIGCSSSSTSSSNTIIDSDYQKMDLDVKNSTSLPQSFMNTPGMLNIDNGNMMLMNGNYDLFSNINFENIMSDETFNNMIFSELNELPDFFNSPSLGFNEQNI
Protein: Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) (Q64604)
Organism: Rattus norvegicus (Rat)
Function: Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Leucine-rich repeat-containing protein 4B
- Catenin beta-1
- PTPRF interacting protein alpha 1
- Tyrosine-protein phosphatase non-receptor type 1
- Insulin receptor
- Tyrosine-protein phosphatase non-receptor type 11
- Insulin receptor substrate 1
- Insulin receptor substrate 2
- Insulin receptor substrate 3
- PPFIA binding protein 1
Sequence:
MAPEPAPGRRMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQIGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGNVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLPPQERIIKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFPQNLRVTGLTTSTTELAWDPPVLAERNGRITNYTVVYRDINSQHELQNVTGDVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPMEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGTSAGGLQHLVSIRTAPDLLPQKPLPASAFIEDGRFSLSMPQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWSTPEELELDELLEAIEQGEEKQRRRRRQAERLKPYVAAQVDELPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRIATVVMMTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLAGSKARASRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT
Protein: CBEL protein, formerly GP34 (O42830)
Organism: Phytophthora nicotianae (Potato buckeye rot agent) (Phytophthora parasitica)
Interaction partners:
Sequence:
MIARITVVFAGLVAVVSGACSTPSFGNCGSDAAGVSCCQSTQYCQPWNANYYQCLDLPAKCAQQFPNVDFNGDDIQTIYGIQPGECCTRCSETAGCKAYTFVNSNPGQPACYLKSGTGTRTPSVGAVSGILTGTSTTPTPTPTMTPTPTPTTSSPTCTTAPYGSCGSSNGATCCPSGYYCQPWNDSFYQCIQPPAKCSKQLTDKDYYGNDIKTVYVSLPSLCCDACASTAGCKAYTYINNNPGQPVCYLKSAAGTATTKIGAVSGTLN
Protein: p44-32 outer membrane protein (Q2GIJ9)
Organism: Anaplasma phagocytophilum (strain HZ)
Interaction partners:
Sequence:
MMSLAIVMAGNDVRAHDDVSALDTGGAGYFYVGLDYSPAFSKIRDFSIRESNGETKAVYPYLKDGKSVKLESHKFDWNTPDPRIGFKDNMLVAMEGSVGYGIGGARVELEIGYERFKTKGIRDSGSKEDEADTVYLLAKELAYDVVTGQTDKLTAALAKTSGKDIVQFANAVKITNSTIDGKVCSGKHAALVPNKGKDYDADAKESNTNAHKTAQCSGLADSAATGPKSFSGFVGAVKVGEGKNWPTGRAASATSNETVVGPTNSNATAVAKDLVALNSDEKTIVAGLLAKTIEGGEVVEIRAVSSTSVMVNACYDLLSEGLGVVPYACVGLGGNFVGVVDGHITPKLAYRLKAGLSYQLSPEISAFAGGFYHRVVGDGVYDDLPAQRLVDDTSPAGRTKDTAIANFSMAYVGGEFGVRFAF
Protein: Bidirectional sugar transporter SWEET2 (AtSWEET2) (Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 2) (Q9LH79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
Interaction partners:
- Monosaccharide-sensing protein 2
Sequence:
MDVFAFNASLSMCKDVAGIAGNIFAFGLFVSPMPTFRRIMRNKSTEQFSGLPYIYALLNCLICLWYGTPFISHSNAMLMTVNSVGATFQLCYIILFIMHTDKKNKMKMLGLLFVVFAVVGVIVAGSLQIPDQLTRWYFVGFLSCGSLVSMFASPLFVINLVIRTKSVEFMPFYLSLSTFLMSASFLLYGLFNSDAFVYTPNGIGTILGIVQLALYCYYHRNSIEEETKEPLIVSYV
Protein: Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) (Glutamyl--tRNA ligase regulatory factor) (P12047)
Organism: Bacillus subtilis (strain 168)
Function: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability.
Interaction partners:
- Adenylosuccinate synthetase
- N5-carboxyaminoimidazole ribonucleotide synthase
- Amidophosphoribosyltransferase
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bifunctional purine biosynthesis protein PurH
- N5-carboxyaminoimidazole ribonucleotide mutase
- Phosphoribosylformylglycinamidine synthase subunit PurL
- Phosphoribosylformylglycinamidine cyclo-ligase
- Phosphoribosylglycinamide formyltransferase
- Phosphoribosylamine--glycine ligase
Sequence:
MIERYSRPEMSAIWTDENRFQAWLEVEILACEAWAELGVIPKEDVKVMRENASFDINRILEIEKDTRHDVVAFTRAVSESLGEERKWVHYGLTSTDVVDTALSYLLKQANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWHEEMKRNLERFKQAKAGIEVGKISGAVGTYANIDPFVEQYVCEKLGLKAAPISTQTLQRDRHADYMATLALIATSIEKFAVEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSENMTGMARVIRGYMMTAYENVPLWHERDISHSSAERIILPDATIALNYMLNRFSNIVKNLTVFPENMKRNMDRTLGLIYSQRVLLALIDTGLTREEAYDTVQPKAMEAWEKQVPFRELVEAEEKITSRLSPEKIADCFDYNYHLKNVDLIFERLGLA
Protein: GTPase activating protein of Rab-like GTPase, putative (Q4GYQ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVLSAAIEKRQHPTEQGGEEMQWMGSSPRCPSSVEACRRICIGEGLANNDVRISGWLLLCVSNTKEATTSPLSKFDSAANKGCGTKLNNDVDDGDSSGSNRAEVGGNGNASSMKSDLHDSVSRSEAPAGTTNTSSSSLSETHGDSAVVSKRKEKPVDEDVDAKDHVEEGYGDSAQPVDALEESSTISDSWGADLPANCHARVIVADVKRSLWKLYPNETVREKKRKMLCNILAQILSNNPERHYYQGLHEMVGFVMYVMEGAREADIVAVCSRLLVQQWRSFSCKQLERSQSMMYAMHTIVVKEEKILAEELEACSVGPESHYAMPWLITWYTHVCDDVEALSRLFDFLVASEDENTVIFFTAALMLHEREQIIGIIKEVKSSCCDCDDSDGTATAEEINKTLVMAQVYSRLVRLPKEVLRRDRARDLESIIRRATVLHEKYLSYANDVRGRFMRNIVSVSTTSDSSGKWHQCKRWLRFSLERRWVNAGFICIIAIFAFWYRESTSRGVTLLGNWITDLYTVSCSIRSSVFTV
Protein: Synaptonemal complex protein 4 (Q9N5K3)
Organism: Caenorhabditis elegans
Function: Constitutes an element of the transverse filaments of the synaptonemal complex (SC), formed between homologous chromosomes during meiotic prophase I, and is required for the assembly of the central region of the SC. Required for chromosome synapsis and chiasma formation between homologous chromosomes during meiosis, mechanisms that are crucial for crossover formation and meiotic recombination.
Subcellular location: Chromosome {ECO:0000269|PubMed:19798442, ECO:0000269|PubMed:21840865, ECO:0000269|PubMed:28346135}. Note=Localizes to chromosomes during meiotic prophase I (PubMed:19798442). During leptotene and zygotene, localizes in foci on chromosomes (PubMed:19798442). Localizes to the central region of the synaptonemal complex at the interface between synapsed chromosomes throughout pachytene (PubMed:19798442, PubMed:21840865, PubMed:28346135). During diplotene, becomes concentrated towards one end of each chromosome (PubMed:19798442). Localizes to the short axes of the bivalents during diakinesis and disappears from chromosomes by the end of diakinesis (PubMed:19798442). {ECO:0000269|PubMed:19798442, ECO:0000269|PubMed:21840865, ECO:0000269|PubMed:28346135}.
Interaction partners:
- Synaptonemal complex protein 3
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- PH domain-containing protein
- HORMA domain-containing protein
- Meiotic recombination protein spo-11
- HORMA domain-containing protein
- Protein MRVI1
- Cyclin N-terminal domain-containing protein
- HORMA domain-containing protein
- Long arms of the bivalent protein 1
Sequence:
MSFPTLQVRPNEKNPKVLRCHEFLRQSNQLVERNMINTEGRKMLAKLLTKMVSEAKGIYALDERRAELAKSGKLQEKLKSAYQTSLTVMEDRLHIAELSRQVQEKKLTVQQKYYECDDLRKSVQETNTEARRVQEINEQRLVDTTRATEELIVKSASILKNLENSSDVHKLRAMEEEKRILEEVVEGLRDQKKCLADDIRTKKATLKAESKKSFEKTVIECAKHYKLHQSLMPKLDKSKRSLETLKDEEENRRICGSLSLDETMQFDRSFILASMDKTNKPEKAVQQLTSKSSEVSITPQISETAKSSFSKEPIPTQHPMEVGEEPVIEHSAEESVHIEPPNVTEIREVVPQITIQPTRQDSVVQRDAEELDTSAVPSPQPESILDEPEEEEEELSNHENHADQSMDVMEVDQEVPEESPMEVGEQEEIEQPSVFKDILATEQAALSQEQEPEIVEKQADNDVQFVDDQQVGAQLDVEDEEEVMSENGSNKSNNFSFNFFGNSKGTSAGEGGGEGNFDFNFDGIGAGDDGSNNGGSTGDLDFLNYDGEDEGKGSGNTQSDPFGFASNGNAAGGGGDGSFNFNFDGDGEGGATSGAGGNSTSFFNF
Protein: T. brucei spp.-specific protein (Q581V7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSVRSDTFLGGRGSRVPSTGFNSQCAKTHAYQRGADGGFMGRKIYCQPVPLYCCSLLFMQWYPVTLMDASFLVTAITKQKKLEKIGLHSDHHHDFSHMA
Protein: Inter-alpha-trypsin inhibitor heavy chain H5 (ITI heavy chain H5) (ITI-HC5) (Inter-alpha-inhibitor heavy chain 5) (Q8BJD1)
Organism: Mus musculus (Mouse)
Function: May act as a tumor suppressor.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MLLLLGLCLGLPLFSESQEEARSWDDTSEQVVLRVPRQLRLLQRLKTKPLMAEFSVKSTIISRYAFTTVSCRMLNRASEDQEAEFQMQIPESAFITNFTMLIGDSVYRGEITQKDKKSSESVKDKRNRTSDDNEENGSDMFKASLVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLVGRLTVEVDILERSGITSLEVLPLHNSRKKGSGKAEGDVGPPPSTLINQNETFAKVIFKPTVVQQAKIAQNGILGDFIVRYDVEREQNIGDIQVLNGYFVHYFAPKNLPPLPKNVVFVLDISASMVGAKLQQTREALVTILNDLRPQDRFNIIGFSNRIKMWKDHLLPVTPDNIRNGKIYMYHLSPTGGTDINGALQAAIKLLNNYVAQNDIEDRSVSLIIFLTDGKPTFGETNTLKILSNTKEATRGQICIFTVGIGDDVDFKLLEKLSLENCGLTRRVHEEDKAGAQLIGFYDEIRTPLLSDIRIDYPPDVVEHATKTLFPNYFNGSEIVIAGKMVDKKFDQLHVEVTASNSKKFVILKRDIPVEFRKMGNDVSVTPGSARDGGKDLNHIERLWSYLTVKELLSSWRQSNSEQEKEQLRQKAQDLALNYHFLTPFTSMKLRKPGLRTNQLEDTYGMSAATGPATVVQNLREAGKQPEPDLKKTYDPRIKISKTSVDGDPHFVVDFPLSKLTVCFNIDGEPGDILRLVSDHLNSGVTVNGELIGAPAPPNGHKKQRTYFRTITILINRPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSRGLEVSVSANANITVVIQGNIAFVILIHLYKNPAPFQRDHLGFYIANSRGLSDNCHGLLGQFLNQDAKLVGAPEEYGKNLSNQPFPRAEGMPEAILKVKGRRVPVVWKQRKIYNGQAQVDCWFDRNNAAKLIDGVYKDYLASHPFDTESALGLSTPRKPETDRPHEESV
Protein: NIF3-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein) (Q9GZT8)
Organism: Homo sapiens (Human)
Function: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11124544, ECO:0000269|PubMed:12951069}. Nucleus {ECO:0000250|UniProtKB:Q9EQ80}. Note=Interaction with COPS2 may regulate localization to the nucleus. {ECO:0000250|UniProtKB:Q9EQ80}.
Interaction partners:
- THO complex subunit 7
- COP9 signalosome complex subunit 2
- Max-like protein X
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
- Max dimerization protein 4
- Peptidyl-prolyl cis-trans isomerase-like 3
- Transcriptional adapter 3
- Pyruvate kinase PKLR
- Vacuolar protein sorting-associated protein 28 homolog
Sequence:
MLSSCVRPVPTTVRFVDSLICNSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEVLQKKADLILSYHPPIFRPMKRITWNTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGACTSRPIHPSKAPNYPTEGNHRVEFNVNYTQDLDKVMSAVKGIDGVSVTSFSARTGNEEQTRINLNCTQKALMQVVDFLSRNKQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIDRIKRHLKLSHIRLALGVGRTLESQVKVVALCAGSGSSVLQGVEADLYLTGEMSHHDTLDAASQGINVILCEHSNTERGFLSDLRDMLDSHLENKINIILSETDRDPLQVV
Protein: Par-3 family cell polarity regulator (Q5VWV2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS
Protein: Ceramide synthase 2 (Q3T1K1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Acid ceramidase
- 3-ketodihydrosphingosine reductase
- Sphingolipid delta
- Sphingolipid delta
- Ceramide kinase
- Ceramide glucosyltransferase
- Alkaline ceramidase
- Neutral ceramidase
- Phosphatidylcholine:ceramide cholinephosphotransferase 1
- Alkaline ceramidase
Sequence:
MLQTLYDYFWWERLWLPVNLTWADLEDKDGRVYAKASDLYITLPLALLFLIIRYFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYLTVGKQPKQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVDKPWFYDLRKVWEGYPIQSIIPSQYWYYMIELAFYWSLLFSIASDVKRKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNLFIVFAVVFIITRLVIMPFWILHCTMIYPLEFYPAFFGYYFFNSMMVVLQMLHVFWAYFIVRMAHKFITGKELGRSQIRDVESERPSSWGRDPQSEEESSSREAALCIQWLHSSTAVPCLPHCPLHSCNPK
Protein: Protein 4.1 (Band 4.1) (Erythrocyte membrane protein band 4.1) (A0A2R8YD30)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQKLAEKTEDLIRMRKKKRERLDGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE
Protein: Reticulon-like protein B1 (AtRTNLB1) (VirB2-interacting protein 1) (Q9SUR3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9SH59}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:15060130}; Multi-pass membrane protein {ECO:0000269|PubMed:15060130}.
Interaction partners:
- Reticulon-like protein B21
- Reticulon-like protein B18
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
- Reticulon-like protein B17
- 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2
- Dehydrin HIRD11
- At2g44060
Sequence:
MAEEHKHDESVIAPEPAVEVVERESLMDKISEKIHHGGDSSSSSSSSDDEDEKKKTKKPSSPSSSMKSKVYRLFGREQPVHKVLGGGKPADIFMWKNKKMSGGVLGGATAAWVVFELMEYHLLTLLCHVMIVVLAVLFLWSNATMFINKSPPKIPEVHIPEEPILQLASGLRIEINRGFSSLREIASGRDLKKFLIAIAGLWVLSILGGCFNFLTLAYIALVLLFTVPLAYDKYEDKVDPLGEKAMIELKKQYAVLDEKVLSKIPLGPLKNKKKD
Protein: Ionotropic receptor 75a (A0A1J0M738)
Organism: Drosophila sechellia (Fruit fly)
Function: Olfactory receptor for propionic, butyric and 2-oxopentanoic acids.
Subcellular location: Cell membrane {ECO:0000305|PubMed:27776356}; Multi-pass membrane protein {ECO:0000255}. Cell projection, dendrite {ECO:0000269|PubMed:27776356}.
Interaction partners:
- GM18071
- GM22253
- GM26714
- GM23108
- GM19647
- GM14265
- GM18791
Sequence:
MQLVQLANFVLDNLVQSRIGFIVLFHCWQSDESLKFAEQFMKPIHPILVYHQFVQMRGVLNWSHLELNYMGHTQPTLAIYVDIKCDQAQDLLEEASREQIYNQHYHWLLVGNQSELEFNDLFALFNISIDADVSYVKEQIQDNNDSVAYAVYDVYNNGKIIGGQLNVTGSHEMSCDPFKCRRTRYLSSLQKRSKYGNREQLTDVVLRVATVVTXRPLTLSDDELIRFLSQENDTHIDSLARFGFHLTLILRDLLYCKMKFIFSDSWSKSDVVGGSVGAVVDQTADLTASPSLATEGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMECKRMQKRWRLDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMQQLAESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNPELWLPAEQGVLRVKANPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEKLLYTHLHRNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCEAQNFVITVGMEYVAPLLLMLICADILVVVILLVELAWKRFFTRPLTIHP
Protein: DNA polymerase delta subunit 4 (O59835)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Appears to have a role in the stabilization of the DNA polymerase delta complex.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA polymerase delta catalytic subunit
- DNA polymerase delta subunit 3
- DNA polymerase subunit delta-2
- Proliferating cell nuclear antigen
- DNA polymerase alpha catalytic subunit
- Replication factor A protein 3
- Replication factor A protein 1
- Replication factor A protein 2
- DNA polymerase zeta catalytic subunit
- DNA polymerase zeta processivity subunit
Sequence:
MKKRTTQAKKSGQNTNIRDVFPHVVRSNSSQSHIGKKVSSEQSPTPDVTITTKTLDERIKEDDELSKEVEEAWNQIMAERISEPIHCENITKVEFILHHFDTTARYGPYLGMTRMQRWKRAKNFNLNPPETVGKILMLEEADEENRKRESLFYDLQTIPG