wanglab/gogpt-training-data huggingface dataset:
Protein: Large ribosomal subunit protein uL14 (60S ribosomal protein L23-A) (A0A1D8PPT5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:35613268}.
Interaction partners:
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein uL6
- Small ribosomal subunit protein eS24
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein uL3
- Small ribosomal subunit protein RACK1
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein eL18
- Small ribosomal subunit protein uS9
Sequence:
MSGSGASGNKFRMSLALPVGAVMNCADNSGARNLYVLAVKGTGARLNRLPAAAAGDMVMATVKKGKPELRKKVMPAIVIRQSKPWRRRDGVYLYFEDNAGVIVNPKGEMKGSAITGPVAKECADLWPRIASNSGVVV
Protein: Probable family 17 glucosidase SCW10 (EC 3.2.1.-) (Soluble cell wall protein 10) (Q04951)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:9748433}.
Interaction partners:
- Probable circularly permuted 1,3-beta-glucanase TOS1
- 1,3-beta-glucanosyltransferase GAS1
- Probable secreted beta-glucosidase SUN4
- Probable family 17 glucosidase SCW4
- Cell wall mannoprotein CIS3
- Protein PRY2
- Tubulin beta chain
- 1,3-beta-glucanosyltransferase GAS5
- Endochitinase
- Probable 1,3-beta-glucanosyltransferase GAS3
Sequence:
MRFSNFLTVSALLTGALGAPAVRHKHEKRDVVTATVHAQVTVVVSGNSGETIVPVNENAVVATTSSTAVASQATTSTLEPTTSANVVTSQQQTSTLQSSEAASTVGSSTSSSPSSSSSTSSSASSSASSSISASGAKGITYSPYNDDGSCKSTAQVASDLEQLTGFDNIRLYGVDCSQVENVLQAKTSSQKLFLGIYYVDKIQDAVDTIKSAVESYGSWDDITTVSVGNELVNGGSATTTQVGEYVSTAKSALTSAGYTGSVVSVDTFIAVINNPDLCNYSDYMAVNAHAYFDENTAAQDAGPWVLEQIERVYTACGGKKDVVITETGWPSKGDTYGEAVPSKANQEAAISSIKSSCGSSAYLFTAFNDLWKDDGQYGVEKYWGILSSD
Protein: Protein tyrosine phosphatase Meg2, isoform G (EC 3.1.3.-, EC 3.1.3.48) (M9MS42)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAVKQFIDLCNNLGANCSTTTATSPSTSSSSASSTQNLIAVVPPQLQQLQVQLPAPGGGGGAGAGGGGGGGGGAAPVRRHISHTTAVKFLYARKFDIPRAVSLYEQHEQIRLKEYLYNIDPDVEPLRSELQTGKFTILPARTSSGAAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSETQRAGLVFIYDMSGSKYSNFDYDLSQKILTLLKGGYPARLKKVLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVPQLALHVPRKALPIHLGGTLEVDHATWLLSCRQSMTNREDELLANIVGVGGGSGSGSAAGSAAIVSTNGTETEAATTAATIISAVHQLGDNNTTVVTVSNGVGPAGSASGGATTAASAATEPNENITINGLSPSHRQAANNSSSSSSSAATVANPLKLNTSGSADNNSTITNATTAAGAAGAAAGTTTNGGGEFWSENPPSSASSGFSDDDSLAGQEGDPKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLAGFDEREPDSE
Protein: phosphatidylinositol-3,5-bisphosphate 3-phosphatase (EC 3.1.3.95) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (A0A8I6AT43)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
Sequence:
MASLQGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRLHIKFKDSVINVPLRMIDSVESRDMFQLHIACKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRASGGSLSAGTNDASEACDTDFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENAEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPGSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVSLEPWHSNPEGAEAVIESGVGSPQLTVGDVGLPPPLPSSQKDYLSNKPFKGHKSCSLSYKLLNTSVSWEMKNTSEIKVLEETEALAPGPPAREEQSRTSDGLGKPPEQCPEKEATSSLSNVSSKCGGACDFPGEPPQDSFTGTPQQPHLDSMQAVPIRCTPDHGQGSLCNPPSAASQTLQEPNTDLISQDPPGSMAGISYQEQPSSVSDLIYKKEDAGKRGSKNGQLVENPRFGKMPLELARKPISQSQISEFSFLGSNWDSFQGMMTSFPSGETTPRRLLAYGCCSKRPSNKHIRAAAPCFGGQWAQREGMKSPVCSSHSNGHCTGPGGKNNRMWFSSHPKQVSSTKPSLLSCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQHLKKPIATASS
Protein: Adenine DNA glycosylase (EC 3.2.2.31) (E5KP28)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRKPRAAVGSGHRKQAASQEGRQKHAKNNSQAKPSACDAGLARQPEEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLCRARQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEPWDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPSVTWEPSEQLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQTPVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKPRMGQQVLDNFFRSHISTDAHSLNSAAQ
Protein: PRA1 family protein A3 (AtPRA1.A3) (Q8W115)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular location: Endosome membrane {ECO:0000269|PubMed:18583532}; Multi-pass membrane protein {ECO:0000269|PubMed:18583532}.
Interaction partners:
- PRA1 family protein E
- PRA1 family protein G1
- PRA1 family protein B5
- PRA1 family protein H
- PRA1 family protein G2
- PRA1 family protein C
- PRA1 family protein F3
- PRA1 family protein B1
- PRA1 family protein F4
- PRA1 family protein B4
Sequence:
MDWDSVAAEDVIEALREVEWSASPRSLAEFFSRFAFPRSFSKWMSRLKCNLYYYRTNYFILFVFVLGLALITRPLAILGAALTALSLAFLNDSFAATFNEKMIRTIRHFSPHLAAKMRPPHMPVIRGRSATRKTVYICGQPRLVFVLLGLTASFVLWFTSCGLLWVLYALTTALLMILLHASLRTPNLKARLNTFREEFRAVWRNYSEL
Protein: cAMP-dependent protein kinase type II-beta regulatory subunit (P12369)
Organism: Rattus norvegicus (Rat)
Function: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with PJA2 in the cytoplasm and at the cell membrane. {ECO:0000250}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase type II-alpha regulatory subunit
- Protein kinase cAMP-dependent type I regulatory subunit beta
- cAMP-dependent protein kinase type I-alpha regulatory subunit
- 5'-AMP-activated protein kinase subunit beta-2
- Hormone-sensitive lipase
- A-kinase anchor protein 1, mitochondrial
- Protein kinase cAMP-dependent X-linked catalytic subunit
- Serine/threonine-protein kinase PLK1
Sequence:
MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGTPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEENGAVEIARCLRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
Protein: Forkhead box N2 (Q8BSS2)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00089}.
Interaction partners:
Sequence:
MGPVIGMTPDKRAETPGAEKVAGLSQIYKMGSLPEAGDAARPKATLVGSESADDELTNLNWLHESSNLLTNLRLGSEGLPMVSPLYDIEGDEMPSFGPSCYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDRFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLMQALKKQPFSSPQR
Protein: Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) (P70567)
Organism: Rattus norvegicus (Rat)
Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P28289}. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments. {ECO:0000250|UniProtKB:P28289}.
Interaction partners:
- Beta-adducin
- Alpha-adducin
- Nebulin
- Gamma-adducin
- Tropomyosin beta chain
- Tropomyosin alpha-1 chain
- Dematin actin binding protein
- Tropomyosin alpha-4 chain
- Troponin T, slow skeletal muscle
- Myosin light chain 1/3, skeletal muscle isoform
Sequence:
MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKIWVPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNPTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAESLKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILCLVEALPHNTSLVELKIDNQSQPLGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV
Protein: Hydrophobic protein RCI2A (Low temperature and salt-responsive protein LTI6A) (Q9ZNQ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein Brevis radix-like 2
- 14-3-3-like protein G-BOX factor 14 lambda
- Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE
- Prolamin-like protein
- Protein S-acyltransferase 10
- Aquaporin PIP2-1
Sequence:
MSTATFVDIIIAILLPPLGVFLRFGCGVEFWICLVLTLLGYIPGIIYAIYVLTK
Protein: Adenine phosphoribosyltransferase 1 (APRT 1) (EC 2.4.2.7) (P49435)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Adenylosuccinate lyase
- Adenosine kinase
- Adenine deaminase
- GMP synthase
- Adenine phosphoribosyltransferase 2
- Inosine triphosphate pyrophosphatase
- Guanylate kinase
- Adenylate kinase
- Hypoxanthine-guanine phosphoribosyltransferase
- AMP deaminase
Sequence:
MSIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLNAQKEALKK
Protein: Peroxisomal membrane protein 4 (24 kDa peroxisomal intrinsic membrane protein) (P59382)
Organism: Rattus norvegicus (Rat)
Subcellular location: Peroxisome membrane; Multi-pass membrane protein.
Interaction partners:
- Peroxisomal biogenesis factor 19
- Peroxisomal membrane protein 2
- Peroxisomal membrane protein PEX16
- Transmembrane protein 135
- ATP-binding cassette sub-family D member 2
- ATP-binding cassette sub-family D member 1
- Peroxisomal biogenesis factor 11 beta
- Peroxisomal membrane protein PEX13
- ATP-binding cassette sub-family D member 3
- Outer mitochondrial transmembrane helix translocase
Sequence:
MAAPPQLRALLQAVNKLLRQRRYHAALAVIKGFRNGAVYGVKIRAPHALVMTFLFRSGSLQEKLQAILKATYTHSRNLACFVFTYKSLQALQSHVQGGTHQMHSFLAAFIGGLLLFGENNNINSQINMYLTSRVLFALCRLGVEKGYIPALKWDPFPLHTAVIWGLVLWLFEYHRPTLQPSLQSSMTYLYEDSNVWHDLSDFLIFNKSRPSK
Protein: Uncharacterized protein C24B10.16c (Q9P7J0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MFQVIQKELDFGNAMIPKVWIQVIKLNPSSSIFVWGSNVSTCPAGDLALSMPGKSDVVTTKLTGAGSIDDLSTQMSRILSKKFQAQVYTSINLQGDFPNDPEVQSVFTQVIRAVIEIIESSKSS
Protein: Bromodomain PHD finger transcription factor (A2A652)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
SKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRDLKMKREREMAQAVQANAASVPTPSVPAPVPAPAPAAPPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKYVPVPQLCS
Protein: 5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2) (Q8IUZ5)
Organism: Homo sapiens (Human)
Function: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde.
Subcellular location: Mitochondrion {ECO:0000305|PubMed:22241472}.
Interaction partners:
- Hydroxylysine kinase
- Alpha-aminoadipic semialdehyde synthase, mitochondrial
- Alpha-aminoadipic semialdehyde dehydrogenase
- Beta-alanine-activating enzyme
Sequence:
MAADQRPKADTLALRQRLISSSCRLFFPEDPVKIVRAQGQYMYDEQGAEYIDCISNVAHVGHCHPLVVQAAHEQNQVLNTNSRYLHDNIVDYAQRLSETLPEQLCVFYFLNSGSEANDLALRLARHYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLDGQKEWVHVAPLPDTYRGPYREDHPNPAMAYANEVKRVVSSAQEKGRKIAAFFAESLPSVGGQIIPPAGYFSQVAEHIRKAGGVFVADEIQVGFGRVGKHFWAFQLQGKDFVPDIVTMGKSIGNGHPVACVAATQPVARAFEATGVEYFNTFGGSPVSCAVGLAVLNVLEKEQLQDHATSVGSFLMQLLGQQKIKHPIVGDVRGVGLFIGVDLIKDEATRTPATEEAAYLVSRLKENYVLLSTDGPGRNILKFKPPMCFSLDNARQVVAKLDAILTDMEEKVRSCETLRLQP
Protein: Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) (P00471)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Interaction partners:
Sequence:
MKQYQDLIKDIFENGYETDDRTGTGTIALFGSKLRWDLTKGFPAVTTKKLAWKACIAELIWFLSGSTNVNDLRLIQHDSLIQGKTVWDENYENQAKDLGYHSGELGPIYGKQWRDFGGVDQIIEVIDRIKKLPNDRRQIVSAWNPAELKYMALPPCHMFYQFNVRNGYLDLQWYQRSVDVFLGLPFNIASYATLVHIVAKMCNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKLRPKDFVLNNYVSHPPIKGKMAV
Protein: Thromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (P49430)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P24557}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Prostacyclin synthase
- Prostaglandin G/H synthase 1
- Prostaglandin E synthase
- Prostaglandin E synthase 3
- Hematopoietic prostaglandin D synthase
- Prostaglandin E synthase 2
- Prostaglandin-H2 D-isomerase
- Prostaglandin G/H synthase 2
- Prostamide/prostaglandin F synthase
- Prostaglandin E synthase 3
Sequence:
MEVLGLLKFEVSGTVVTVTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPSPFVGNLMFFRQGFWESHLELRERYGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGLEPKLIADSVLMLRDRRWEEVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAFDIQRCYCCFTTNVVASVAFGIEVNSQDAPEDPFVQHCQRVFAFSTPRPLLALILSFPSIMVPLARILPNKNRDELNGFFNTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSAECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVLGQHIPAGSVLEIAVGALHHDPEHWPNPETFDPERFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPETQVPLQLESKSALCPKNGVYVKIVSR
Protein: Catalase isozyme 2 (EC 1.11.1.6) (P12365)
Organism: Zea mays (Maize)
Function: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P25819}. Peroxisome matrix {ECO:0000250|UniProtKB:P25819}.
Interaction partners:
- Trehalase
- CO
- CO
- Carbonic anhydrase
- Acyl-coenzyme A oxidase
- Acyl-coenzyme A oxidase
- 2-Cys peroxiredoxin BAS1, chloroplastic
- 2-Cys peroxiredoxin BAS1, chloroplastic
- 1-Cys peroxiredoxin PER1
- Peroxiredoxin
Sequence:
MDPYKHRPSSAFNAPYWTTNSGAPVWNNDSSLTVGARGPILLEDYHCEKLANFDRERIPERVVHARGASAKGFFEVTHDITHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNWDLVGNNFPVFFIRDGIKFPDMVHALKPNPRTHIQDNWRILDFFSHHPESLHMFSFLFDDVGIPADYRHMDGSGVHTYTLVSRAGTVTYVKFHWRPTCGVRSLMDDEAVRCGANHSHATKDLTDAIAAGNFPEWTLYIQTMDPEMEDRLDDLDPLDVTKTWPEDTFPLQPVGRLVLNRNIDNFFAENEQLAFCPGLIVPGIYYSDDKLLQTRIFSYSDTQRHRLGPNYLLLPANAPKCAHHNNHYDGSMNFMHRHEEVDYFPSRYDAVRNAPRYPIPTAHIAGRREKTVISKENNFKQPGERYRAMDPARQERFITRWVDALSDPRLTHEIRTIWLSNWSQADRSLGQKLASRLSAKPSM
Protein: CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3) (Q00322)
Organism: Mus musculus (Mouse)
Function: Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Transcriptional activator that enhances IL6 transcription alone and as heterodimer with CEBPB (By similarity).
Subcellular location: Nucleus {ECO:0000305|PubMed:7594592}.
Interaction partners:
- CCAAT/enhancer-binding protein beta
- Krueppel-like factor 5
- Peroxisome proliferator-activated receptor gamma
- Cyclic AMP-responsive element-binding protein 1
- Mothers against decapentaplegic homolog 4
- Transcription factor COE1
- Mothers against decapentaplegic homolog 3
- Transcription factor Jun
Sequence:
MSAALFSLDSPVRGTPWPTEPAAFYEPGRVDKPGRGPEPGDLGELGSTTPAMYDDESAIDFSAYIDSMAAVPTLELCHDELFADLFNSNHKAAGAGGLELLQGGPTRPPGVGSVARGPLKREPDWGDGDAPGSLLPAQVAVCAQTVVSLAAAAQPTPPTSPEPPRGSPGPSLAPGTVREKGAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLAGLRQFFKKLPSPPFLPPTGADCR
Protein: DDB1- and CUL4-associated factor 15 (Q66K64)
Organism: Homo sapiens (Human)
Function: Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins. The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3. May play a role in the activation of antigen-presenting cells (APC) and their interaction with NK cells.
Interaction partners:
- RNA-binding protein 39
- DNA damage-binding protein 1
- DET1- and DDB1-associated protein 1
- Cullin-4A
- Cullin-4B
- Protein cereblon
- DDB1- and CUL4-associated factor 16
- E3 ubiquitin-protein ligase RBX1
- DDB1- and CUL4-associated factor 8
- DDB1- and CUL4-associated factor 4
Sequence:
MAPSSKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDFSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDIYVSTVAVPPPGRCAACQDASRAHPGDPNAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAGDRSFCQILYDHSTCPLAPASPPEPQSPELPPALPSFCPEAAPARSSGSPEPSPAIAKAKEFVADIFRRAKEAKGGVPEEARPALCPGPSGSRCRAHSEPLALCGETAPRDSPPASEAPASEPGYVNYTKLYYVLESGEGTEPEDELEDDKISLPFVVTDLRGRNLRPMRERTAVQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPSPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL
Protein: Septin (A0A0R4IN26)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}. Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Midbody {ECO:0000256|ARBA:ARBA00004214}.
Interaction partners:
Sequence:
MIERPDSAVSSVARNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSKDYPGPSQRIKKTVQVEQSKVLIKEGGVQLTLTIVDTPGFGDAVDNSNCWQPVINYIDSKFEDFLNAESRVNRRQMPDNRVHCCLYFIAPSGHGLKPLDIEFMKRLHDKVNVIPLIAKADTLTPEECQLFKKQIMKEIQEHKIKIYEFPDTEDDEDSKLIRKIKEKMPLAVVGSNVVIEVNGRKVRGRQYPWGVAEVENGEHCDFTVLRNMLIRTHMQDLKDVTNNVHYENYRSKKLAAVTCNGVDATKNKGQLTKSPLAQMEEERREHVMKMKKMETEMEQVFEMKVKEKKQKLKDSEAELERRHEQMKKNLEAQYKELEEKRRQFEDEKANWEAQQRILEQQKLDASKTMEKNKKKGKIF
Protein: EF-hand domain-containing protein 1 (Myoclonin-1) (E1BKH1)
Organism: Bos taurus (Bovine)
Function: Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death (By similarity). Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37327785}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q5JVL4}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q5JVL4}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q5JVL4}.
Interaction partners:
- Tektin-3
- Tektin-2
- Parkin coregulated gene protein
- Protein Flattop
- RIB43A-like with coiled-coils protein 2
- Cilia- and flagella-associated protein 52
- Outer dynein arm-docking complex subunit 2
- Tektin-4
- Tektin-1
- Tubulin beta-4B chain
Sequence:
MVSNPVHGLPFLPGTSFKDLTKTAFHRSQTLGYRNGYAVVRRPTVGIGGDRLQVNQLSQADLDELASKIPILTYGQARQAPPAAFVPAHVAFDKKVLKFDAYFQEDVPMSIEEHYRIRQVHIYYYLEDDSMSVIEPVVENSGIPQGKLIKRQRLSKNDRGDHYHWKDLNRGINITIYGKTFRIVDCDKFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPTDFDQLKQFLTFDKQVLRFYAIWDDTDSMFGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRMPKVLVENAKNFPRCVLEISDKEVLEWYTAKDFIVGKPLTILGRTFFIYDCDPFTRQYYQEKFGISDLPRIDMSKKEPPPMKQELPPYNGFGLIEDSAQNCFALIPKAPQKDVIKMLMNENKVLRYLATLESPFPEDKGRRFVLSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPGSSVENPVYYGPSDFFIGAVIEVFGHRFVILDTDDYVLKYMESNAAQYSPEALLSIQNHIRKQEAPAPELDGQQAEEDPGVRDLEALIDTIQKQLKDRPCRDNIREAFQIYDKEASGYVDRETFFKICGSYQLPVDDSLIKELIRMCSHGEDKIDYYNFVRAFSN
Protein: BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) (M0R193)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADDGSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNALNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCSTFTFSLAPPPDLEGLFSLIQQKTELPVTENVQTIPPPYV
Protein: Nexilin (Novel protein (Zgc:103442)) (A2BEV6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTEVMSMADVSTDTHMNNTESMNDIADVDSENTVNEENHKEETHDMCCAPEEVEMNSAADEPKETELPEKEKPKQETGRARKRERVQKTKEEDTSQLENEEKADESHDIDITNMSDVALKQEKLLKTSKPVQRSYIPKLGKEDVKNKFEAMQKAREERNQKRSQEEQKKRREQYVKEREYGRRKQMIKELLASSDEEEEVKPTKIEKSYVPKITGSVKGKFAEMEKQRQEEERKRTDEERKKRAAQEAIEKAKIQKELAKKAEEEGDDSLLVRVVPAKSQKQPGRIKINFEDMEKSREEELKKRTEEEKMKRYDENRRSVRESKRRSVVEQLDDGEPQPKEKEQVTPGKLRLTFEEQEKERQEQQRKQAEEEARRRLEEERKAFEEAKLGMGQEDEDTQDTHGEKEEFRPGKLRLSFEELERQRLEDEHKRVEEERKRRIEEERKAFAEARKSMVINSDDDILLAMINSDGAKPGKLAISFEDLERQRQEEEQKRKEEEAKRRLEEEKRLFAEARKSMSPGVDQDNMTGCGDKEVLDDDETLVRTESQEGLHPGKLEINFEEMLKMKEEAERKRKQEARRQKMEMEKKEFEQLRQEMGEEEINESSEVVSAEYEELTKLKRTGSIQAKSLKSKFEKIKQLTEEEIQKKIEEERARRKEIDEQIKEREAERCQEDEDEDKTSPAKAEDVPFRQKVDMRARFEQMAKAREEEQKRKIEEQKLQRMQFEQQEIDAALQKKKDEEEEEEGSIINGSAAYEDEEDHARSGAPWFKKPLKNQSVVDAEPVRFTVKITGEPKPEVTWWFEGEPLPDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNSRGTAASTCILTIETEDY