wanglab/gogpt-training-data huggingface dataset:
Protein: Peroxiredoxin (EC 1.11.1.24) (Thioredoxin peroxidase) (Thioredoxin-dependent peroxiredoxin) (O58966)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00401}.
Interaction partners:
- 336aa long hypothetical thioredoxin reductase
- Superoxide reductase
- 226aa long hypothetical glutaredoxin-like protein
- Thioredoxin-like fold domain-containing protein
- GTPase HflX
- Phosphoglycerate kinase
- CYTH domain-containing protein
- Prefoldin subunit alpha
- Prefoldin subunit beta
Sequence:
MVVIGEKFPEVEVKTTHGVIKLPDYFTKQGKWFILFSHPADFTPVCTTEFYGMQKRVEEFRKLGVEPIGLSVDQVFSHIKWIEWIKDNLSVEIDFPVIADDRGELAEKLGMIPSGATITARAVFVVDDKGIIRAIVYYPAEVGRDWDEILRLVKALKISTEKGVALPHKWPNNELIGDKVIVPPASTIEEKKQREEAKAKGEIECYDWWFCYKKLE
Protein: Torsin 1A interacting protein 1 (H0YD16)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XLQQQHSEQPPLQPSPVMTRRGLRDSHSSEGEDRGEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTRMQNDSILKSELGNQSPSTSSR
Protein: Protease Do-like 2, chloroplastic (EC 3.4.21.-) (O82261)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine protease that performs the primary cleavage of the photodamaged D1 protein in plant photosystem II.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:11179216}; Peripheral membrane protein {ECO:0000269|PubMed:11179216}; Stromal side {ECO:0000269|PubMed:11179216}.
Interaction partners:
- Protease Do-like 7
- ATP-dependent zinc metalloprotease FTSH 1, chloroplastic
- Glyoxysomal processing protease, glyoxysomal
- Putative defensin-like protein 187
- Putative defensin-like protein 185
- ATP-dependent zinc metalloprotease FTSH 2, chloroplastic
- ATP-dependent zinc metalloprotease FTSH 5, chloroplastic
- Presequence protease 1, chloroplastic/mitochondrial
- ATP-dependent zinc metalloprotease FTSH 8, chloroplastic
- ATP-dependent Clp protease proteolytic subunit 6, chloroplastic
Sequence:
MAASVANCCFSVLNASVKIQSSSISSPWCFVSASSLTPRASSNIKRKSSRSDSPSPILNPEKNYPGRVRDESSNPPQKMAFKAFGSPKKEKKESLSDFSRDQQTDPAKIHDASFLNAVVKVYCTHTAPDYSLPWQKQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKRRGDDRKYVAKVLVRGVDCDIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVGYPLGGDTISVTKGVVSRIEVTSYAHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGVAFQVYRSEETENIGYVIPTTVVSHFLTDYERNGKYTGYPCLGVLLQKLENPALRECLKVPTNEGVLVRRVEPTSDASKVLKEGDVIVSFDDLHVGCEGTVPFRSSERIAFRYLISQKFAGDIAEIGIIRAGEHKKVQVVLRPRVHLVPYHIDGGQPSYIIVAGLVFTPLSEPLIEEECEDTIGLKLLTKARYSVARFRGEQIVILSQVLANEVNIGYEDMNNQQVLKFNGIPIRNIHHLAHLIDMCKDKYLVFEFEDNYVAVLEREASNSASLCILKDYGIPSERSADLLEPYVDPIDDTQALDQGIGDSPVSNLEIGFDGLVWA
Protein: Activating transcription factor 7 interacting protein (F5H1K9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPEGSKAEWKETPCILSVNVKNKQDDDLNCEPLSPHNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATS
Protein: Putative uncharacterized transmembrane protein DDB_G0291600 (Q54EB4)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MNTSTTTKSKNKPPKSTPSTFIKIIEFWFYLIQILTVLFSWRVYFLFIDSKKKIENNNNNDNDNNNTNKNDEKRYLTFKEKVQHNFFCLFTDTLYFMMLIITCTLFFWRLKDTLSLLKKSDSSKYKQIIWDQFSGGFVEFGSFTVLLLLKWPVIFKVFWNKGTEKEDKSTWSQIFMREFSQEVDKNKLGGPKPPTTNTTNFSGNGSSSSTTNATSSSSSQANNKRAMSDDEWRHAFRRDLQNIGFEFDSQTGDVSKFPPTEVMEQYQKSAEFRDLILASGSLKAGSEQQDKNKNNNNNNNNNGPKIEEYDNQKQEEEENEEKETNKQQTQKDDEKETSTTTTSSNKKSKKGKKNKRN
Protein: Erythroid differentiation-related factor 1 (Q3B7T1)
Organism: Homo sapiens (Human)
Function: Transcription factor involved in erythroid differentiation. Involved in transcriptional activation of the globin gene.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Hsp70-binding protein 1
Sequence:
MGDAKEAGAEGPPAGAAARGGLSLLSQGESEESSAQGSALFLGGNEVKSRAVVKYSSAPPRTAFARLEEKTDLKLPPANWLRESAKLGPAGTTILGNSKKSKPFSSFGMAYDFIDSVGNDVDVVSDSENIKKLLKIPYSKSHVSMAVHRIGRTLLLDELDIQELFMRSSQTGDWTWLKEFYQRLIDQKWQRKKKSKEHWYQKAILSKFLYYSINGDGAAQPVSSTAEQQESSSSDQTNDSEGASWPAPFEMPSSVSEDPSASSQGSEPLEPSYIVGHVASAPKEQNLITLFNDGEHSQGLKNDFVRNILWTFEDIHMLVGSNMPIFGGGRYPAVSLRLRDNNKPINVLTGIDYWLDNLICNVPELVMCFHVNGIVQKYEMIKTEEIPNLENSNFSTKVIKDIAQNILSFLKSNCTKEGHTYWLFKASGSDIVKLYDLTTLCEETEDKYQNPFTMPVAILLYKVACNMMMKKNQNKKHYGTIRTLLLNCLKLLDKSRHPQIIASANYMLSELFQLDEPKKEENSESPLNENSDESYSEEEEEMPDSDENGSYSTSSDPSDDSKAVAIIKSVGELSVPEKYKSIHQIRPSCAFPVCHDTEERCRLVLSYVLEGLKSVDSSIKKESDLPAADPSTPIPLKYEDESSRGGPEGLEKQMALFLDKMGSLQKGNYSSQSGMIPGSWQHKMKLQLILKSSKAYYVLSDAAMSLQKYGRALRYIKLALQSHDTYCCLCTNMLSEVLLFLSQYLTLCGDIQLMLAQNANNRAAHLEEFHYQTKEDQEILHSLHRESSCQGFAWATDLSTDLESQLSVSCKCYEAANEILQFSDLKSQNPEHYVQVLKRMGNIRNEIGVFYMNQAAALQSERLVSKSVSAAEQQLWKKSFSCFEKGIHNFESIEDATNAALLLCNTGRLMRICAQAHCGAGDELKREFSPEEGLYYNKAIDYYLKALRSLGTRDIHPAVWDSVNWELSTTYFTMATLQQDYAPLSRKAQEQIEKEVSEAMMKSLKYCDVDSVSARQPLCQYRAATIHHRLASMYHSCLRNQVGDEHLRKQHRVLADLHYSKAAKLFQLLKDAPCELLRVQLERVAFAEFQMTSQNSNVGKLKTLSGALDIMVRTEHAFQLIQKELIEEFGQPKSGDAAAAADASPSLNREEVMKLLSIFESRLSFLLLQSIKLLSSTKKKTSNNIEDDTILKTNKHIYSQLLRATANKTATLLERINVIVHLLGQLAAGSAASSNAVQ
Protein: Hunchback-like protein (Q9XYD3)
Organism: Caenorhabditis elegans
Function: Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein lin-41
- Protein lin-14
- Protein lin-28
- Zinc finger transcription factor lin-29
- LIN-46
- PUM-HD domain-containing protein
- Nuclear hormone receptor family member daf-12
- RING-type E3 ubiquitin transferase
- Period protein homolog lin-42
- Protein argonaute-1
Sequence:
MVQSDSPEELAQRAKPAWRLQQMPVQLSNFVSKTPLIGSEWPPTGDWRSANNNSLGDWNKCCVPGSEIPQHLGPFGNSSLTMLTAQQPGEKIHPDGGYVSPKEDGRKSSEHTNSYDVSASQSPSNDGAQSDSTSDEHIDVECMTETEMDTDEKDSTIKPEDQATPKLEEGSDSKPESTSVEGTSSNYQVTSEPVQMPQMPIPVIPSFLKNSLPAPIPITPTQSANVERSNSPSIEEALLLTLSQQQFAEVFAEAAKIRKSSSESIGFQRSGTSAFLNIEPKEMSMSSANNNNEEAPASTVSACSTPTTTTSASFCRPPGLGPVALPPTQNGQTPMLVCPICGFMCPSKFHFNSHMNTHGDHQCSMCDYTSRTEGRLKKHMRESHTVEEQLRAGFESEPAKESASSPKNLSLSKDGSATSPINEIFNLSTTMASILDSTNNAVSSTSTTEQPSALSALTLDMSSTPSLLSTLAHSSFGVSALDQIKAISENPSFMPEGGINLASALGVVSNAIKGDTPSPEKQSNGECRRSSSGKIKIFKCKQCGHQSLSKDDQWAHARTHIPAEKQLNCQHCNFVTEYKHHLEYHYRNHIGSKPFQCKKCAYNCVNKSMLNSHMKSHTNHYQFRCMDCTYATKYCHSLKLHLKKYNHRRVPEGIEMSGGDSSPPFTSDATITFSPLMKQEIKTETVEPVTSIAQPFPFNPMMGNHGLNFANHMLLNKHLDVGLMGLRNSVMSPLKCSACDFVASSADEKMRHSMSHILNSSNVPTSIASLYNSLNLPSFSHVAPDNDNALESMDCDVKIDDDNITESHCYEEMDQGSDSAVSPTGSSQISSGDEETKKCKSLSLEQISARANGNNSPMSNDSAMEKDGESADDAPHSPSDTTSVPSPPLHSSSIVAPIPITPQPNEFLQSILAQASLLGPLLANRPSAFYCDHCKIPFDTQQVLDSHMRFHTPGNPFMCSDCQYQAFNELSFALHMYQARHQ
Protein: Type IV pilin secretion protein (Q4QNP6)
Organism: Haemophilus influenzae (strain 86-028NP)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004429}.
Interaction partners:
Sequence:
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSLQILQQNCTQIMLNKWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQKIMLYPSMVLGISLLLTLALLLFIAPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWFHQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQGYAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNMGSVIQ
Protein: Olfactory receptor (E9Q0M4)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
Interaction partners:
Sequence:
MVIEFLFSVFPPLYEGGLLFFILLILVYAFIISGNLVIFVAVQLDMALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYPLRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLSLACTDTSLVVIVDAIHAVEILASFLVIALSYIRIIMVILGMPSAEGRHKAFSTCAAHLAVFLLFFGSVAVMYLRFSATYSVFWDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFHQKRDVRAQK
Protein: Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144) (Q8CGF7)
Organism: Mus musculus (Mouse)
Function: Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Pre-mRNA-splicing factor 38A
- Serine/arginine repetitive matrix protein 1
- Zinc finger matrin-type protein 2
- RNA-binding protein 25
- WW domain-binding protein 11
- Probable ATP-dependent RNA helicase DDX46
- Serine/threonine-protein kinase PRP4 homolog
- Splicing factor 3B subunit 4
- Pre-mRNA-splicing factor RBM22
- SNW domain-containing protein 1
Sequence:
MAERGGDGGEGERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGAMPPPPGMMFPPGMPPGTAPGAPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQAVGAPTPTTSSPAPAVSTSTPTSTPSSTTATTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSAPAPTATPVQTVPQPHPQTLPPAVPHSVPQPAAAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLDEKIKEPIKEASEEPLPMETEEEDPKEEPVKEIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGLEDMKKLRHPAPTMLSIQKWQFSMSAIKEEQELMEEMNEDEPIKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK
Protein: Myc proto-oncogene protein (dMyc) (Protein diminutive) (Q9W4S7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes; required for cellular proliferation and growth. Functions in the TORC2-mediated regulation of cell growth, acting downstream of the TORC2 complex. Inhibits the demethylase activity of Lid. Activates transcription of mbm. Has a role in ribosome biogenesis and endoreplication in fat body cells by activating the transcription of LTV1. Able to induce the SCF E3 ubiquitin-protein ligase member archipelago (ago) which functions in its degradation. It may therefore create a negative feedback loop with ago that is regulated by the ubiquitin hydrolase puf. In dopaminergic neurons, regulates dopamine levels by binding to the E-box (E1) of the dopamine decarboxylase Ddc promoter and thereby inhibiting its transcription. This regulation is required to suppress male-male courtship.
Subcellular location: Nucleus {ECO:0000269|PubMed:25999153, ECO:0000269|PubMed:38225354}. Nucleus, nucleolus {ECO:0000269|PubMed:38225354}. Cytoplasm {ECO:0000269|PubMed:25999153}. Note=Translocation from the cytoplasm to the nucleus may be promoted by the TORC2 complex (Lst8 and rictor) (PubMed:25999153). Localization to the nucleolus is dependent on Heatr1 (PubMed:38225354). {ECO:0000269|PubMed:25999153, ECO:0000269|PubMed:38225354}.
Interaction partners:
- Protein max
- Lysine-specific demethylase 5
- Transcriptional coactivator yorkie
- Glutathione S transferase E12, isoform A
- Glutathione S-transferase D1
- Glutathione S transferase D8
- RAC serine/threonine-protein kinase
- Ras-related protein Rab5
- DNA-directed RNA polymerase II subunit RPB3
- Paired amphipathic helix protein Sin3a
Sequence:
MALYRSDPYSIMDDQLFSNISIFDMDNDLYDMDKLLSSSTIQSDLEKIEDMESVFQDYDLEEDMKPEIRNIDCMWPAMSSCLTSGNGNGIESGNSAASSYSETGAVSLAMVSGSTNLYSAYQRSQTTDNTQSNQQHVVNSAENMPVIIKKELADLDYTVCQKRLRLSGGDKKSQIQDEVHLIPPGGSLLRKRNNQDIIRKSGELSGSDSIKYQRPDTPHSLTDEVAASEFRHNVDLRACVMGSNNISLTGNDSDVNYIKQISRELQNTGKDPLPVRYIPPINDVLDVLNQHSNSTGGQQQLNQQQLDEQQQAIDIATGRNTVDSPPTTGSDSDSDDGEPLNFDLRHHRTSKSGSNASITTNNNNSNNKNNKLKNNSNGMLHMMHITDHSYTRCNDMVDDGPNLETPSDSDEEIDVVSYTDKKLPTNPSCHLMGALQFQMAHKISIDHMKQKPRYNNFNLPYTPASSSPVKSVANSRYPSPSSTPYQNCSSASPSYSPLSVDSSNVSSSSSSSSSQSSFTTSSSNKGRKRSSLKDPGLLISSSSVYLPGVNNKVTHSSMMSKKSRGKKVVGTSSGNTSPISSGQDVDAMDRNWQRRSGGIATSTSSNSSVHRKDFVLGFDEADTIEKRNQHNDMERQRRIGLKNLFEALKKQIPTIRDKERAPKVNILREAAKLCIQLTQEEKELSMQRQLLSLQLKQRQDTLASYQMELNESRSVSG
Protein: Alpha-amylase (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) (P56634)
Organism: Tenebrio molitor (Yellow mealworm beetle)
Interaction partners:
Sequence:
QKDANFASGRNSIVHLFEWKWNDIADECERFLQPQGFGGVQISPPNEYLVADGRPWWERYQPVSYIINTRSGDESAFTDMTRRCNDAGVRIYVDAVINHMTGMNGVGTSGSSADHDGMNYPAVPYGSGDFHSPCEVNNYQDADNVRNCELVGLRDLNQGSDYVRGVLIDYMNHMIDLGVAGFRVDAAKHMSPGDLSVIFSGLKNLNTDYGFADGARPFIYQEVIDLGGEAISKNEYTGFGCVLEFQFGVSLGNAFQGGNQLKNLANWGPEWGLLEGLDAVVFVDNHDNQRTGGSQILTYKNPKPYKMAIAFMLAHPYGTTRIMSSFDFTDNDQGPPQDGSGNLISPGINDDNTCSNGYVCEHRWRQVYGMVGFRNAVEGTQVENWWSNDDNQIAFSRGSQGFVAFTNGGDLNQNLNTGLPAGTYCDVISGELSGGSCTGKSVTVGDNGSADISLGSAEDDGVLAIHVNAKL
Protein: Probable family 17 glucosidase SCW4 (EC 3.2.1.-) (Soluble cell wall protein 4) (P53334)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:9748433}.
Interaction partners:
- Cell wall mannoprotein CIS3
- Probable circularly permuted 1,3-beta-glucanase TOS1
- Probable secreted beta-glucosidase SUN4
- Probable family 17 glucosidase SCW10
- Tubulin beta chain
- 1,3-beta-glucanosyltransferase GAS5
- Endochitinase
- Glucan 1,3-beta-glucosidase I/II
- Cell wall mannoprotein HSP150
- 1,3-beta-glucanosyltransferase GAS1
Sequence:
MRLSNLIASASLLSAATLAAPANHEHKDKRAVVTTTVQKQTTIIVNGAASTPVAALEENAVVNSAPAAATSTTSSAASVATAAASSSENNSQVSAAASPASSSAATSTQSSSSSQASSSSSSGEDVSSFASGVRGITYTPYESSGACKSASEVASDLAQLTDFPVIRLYGTDCNQVENVFKAKASNQKVFLGIYYVDQIQDGVNTIKSAVESYGSWDDVTTVSIGNELVNGNQATPSQVGQYIDSGRSALKAAGYTGPVVSVDTFIAVINNPELCDYSDYMAVNAHAYFDKNTVAQDSGKWLLEQIQRVWTACDGKKNVVITESGWPSKGETYGVAVPSKENQKDAVSAITSSCGADTFLFTAFNDYWKADGAYGVEKYWGILSNE
Protein: Putative protein-lysine deacylase ABHD14B (Alpha/beta hydrolase domain-containing protein 14B) (V9HW87)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAASVEQREGTIQVQGQALFFREALPGSGQARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGHSKEAAAPAPIGELAPGSFLAAVVDALELGPPVVISPSLSGMYSLPFLTAPGSQLPGFVPVAPICTDKINAANYASVKTPALIVYGDQDPMGQTSFEHLKQLPNHRVLIMKGAGHPCYLDKPEEWHTGLLDFLQGLQ
Protein: Uncharacterized protein (Q582T1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Transmembrane protein
- Uncharacterized protein
- Uncharacterized protein
- ATP synthase alpha chain
- Uncharacterized protein
- Uncharacterized protein
- ATPase subunit 9, putative
Sequence:
MLRKTPLFAMATTRKALVGNGPTFSTGGECMNTCDIQNAFPMNDRGVRSSSPFQEPNTAIYDSYLAWTYFQPMDVHIEKLPAPEAKYYQRHTKKPWDVSSTELTEIQSRKKYFQTLGYLVAFIYLYFLMPKEKSFSGLSGPDGHWIMLPKGRPELF
Protein: Nucleoporin 88 (J3KMX1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
Sequence:
MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRSVANPAFLNCFTQLRKIKVETLFLRASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
Protein: PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (Q8R1G6)
Organism: Mus musculus (Mouse)
Function: Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity).
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes at the cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN) (By similarity). {ECO:0000250}.
Interaction partners:
Sequence:
MALTVDVAGPAPWGFRISGGRDFHTPIIVTKVTERGKAEAADLRPGDIIVAINGQSAENMLHAEAQSKIRQSASPLRLQLDRSQTASPGQTNGEGSLEVLATRFQGSLRTHRDSQSSQRSACFSPVSLSPRPCSPFSTPPPTSPVALSKEDMIGCSFQSLTHSPGLAAAHHLTYPGHPTSQQAGHSSPSDSAVRVLLHSPGRPSSPRFSSLDLEEDSEVFKMLQENRQGRAAPRQSSSFRLLQEALEAEERGGTPAFVPSSLSSQASLPTSRALATPPKLHTCEKCSVNISNQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWVGNELYCEKHARQRYSMPGTLNSRA
Protein: Limpet, isoform D (Limpet, isoform H) (RE32370p) (Q8IQQ3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVKMLDLDRHAECPLWAALASSDVPWTGMDYACLNVLSIYCKVFDRKEIYDLIVRKTCQSCKCPREAHAIYQQQTTNVHERLGFKLVSPADSGVEARDLGFTWVPPGVRASSRINRYFEQLPDEMVPRLGSEGACSRERQISYQLPKQDLSLEHCKHLEVQHEASFEDFVTARNEIALDIAYIKDAPYDEHCAHCDNEIAAGELVVAAPKFVESVMWHPKCFTCSTCNSLLVDLTYCVHDDKVYCERHYAEMLKPRCAGCDELIFSGEYTKAMDKDWHSGHFCCWQCDESLTGQRYVIRDDHPYCIKCYENVFANTCEECNKIIGIDSKDLSYKDKHWHEACFLCFKCHLSLVDKQFGAKADKIYCGNCYDAQFASRCDGCGEVFRAGTKKMEYKTRQWHENCFCCCVCKTAIGTKSFIPREQEIYCAGCYEEKFATRCIKCNKVITSGGVTYKNEPWHRECFTCTHCNITLAGQRFTSRDEKPYCAECFGELFAKRCTACVKPITGIGGTRFISFEDRHWHHDCFVCASCKASLVGRGFITDGPDILCPDCAKQKLM
Protein: Beta-1,4-galactosyltransferase (Beta-1,4-GalTase) (EC 2.4.1.-) (B2RAZ5)
Organism: Homo sapiens (Human)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU368121}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU368121}.
Interaction partners:
Sequence:
MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKGKTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKALQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLEALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSREQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAERMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA
Protein: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) (P00423)
Organism: Bos taurus (Bovine)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:27605664, ECO:0000269|PubMed:31533957}; Single-pass membrane protein {ECO:0000269|PubMed:27605664, ECO:0000269|PubMed:31533957}.
Interaction partners:
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome c oxidase subunit 3
- Cytochrome b
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome b-c1 complex subunit 9
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase subunit 7A1, mitochondrial
- Cytochrome c oxidase subunit 1
- Cytochrome b-c1 complex subunit 10
- Cytochrome c oxidase subunit 5A, mitochondrial
Sequence:
MLATRVFSLIGRRAISTSVCVRAHGSVVKSEDYALPSYVDRRDYPLPDVAHVKNLSASQKALKEKEKASWSSLSIDEKVELYRLKFKESFAEMNRSTNEWKTVVGAAMFFIGFTALLLIWEKHYVYGPIPHTFEEEWVAKQTKRMLDMKVAPIQGFSAKWDYDKNEWKK
Protein: C-X-C motif chemokine 5 (ENA-78(1-78)) (Epithelial-derived neutrophil-activating protein 78) (Neutrophil-activating peptide ENA-78) (Small-inducible cytokine B5) [Cleaved into: ENA-78(8-78); ENA-78(9-78)] (P42830)
Organism: Homo sapiens (Human)
Function: Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
Subcellular location: Secreted.
Interaction partners:
- C-C motif chemokine 20
- C-X-C chemokine receptor type 2
- C-X-C motif chemokine 3
- C-X-C chemokine receptor type 1
- Growth-regulated alpha protein
- C-X-C motif chemokine 2
- Eotaxin
- C-X-C motif chemokine 14
- Cytokine SCM-1 beta
- C-X-C chemokine receptor type 4
Sequence:
MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
Protein: endothelin-converting enzyme 1 (EC 3.4.24.71) (A0A8I6ATJ1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000256|ARBA:ARBA00004250}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004194}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004194}. Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MNVALQELGSGGSMVEYKRAKLQDEELPEVTVEGRAIQDSLEVGSQKRTRQLFGSHTQLELVLAGLILVLAALLLGCLVALWVQYHRDPVHSTCITEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPSGRSRWNTFNSLWDQNQAILKHLLENSTFNSSSEAERKTRSFYLSCLHLERIEKLGAKPLQDLIDKIGGWNITGPWDEDNFMEVLKAVAGTYRAAPFFTVYVGADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLAAYLDYMVELGMLLGGQPTSTRAQMQQVLELEIQLATITVPQDQRRDEEKIYHKMSISELQTLAPSMDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKAEGMISEIRAAFEETLENLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPRELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDQEGNLRPWWQNESLTAFQNHTACMEEQYNQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Protein: Nigrocin-2ISb (F1T157)
Organism: Odorrana ishikawae (Ishikawa's frog) (Rana ishikawae)
Function: Has antimicrobial activity against Gram-negative bacterium E.coli ATCC 8739 (MIC=50 ug), against Gram positive bacteria S.aureus ATCC 6538 (MIC=3.1 ug), methicillin-resistant S.aureus ATCC 43300 (MIC=12.5 ug), B.subtilis ATCC 6633 (MIC=12.5 ug) and against fungus C.albicans ATCC 90028 (MIC=50 ug).
Subcellular location: Secreted {ECO:0000305|PubMed:21193000}.
Interaction partners:
Sequence:
MFTLKKSMLLLFFLGTINLSLCQEERDAEEERRDEDNAKMEEIKRGILGTVFKAGKGIVCGLTGLC