wanglab/gogpt-training-data huggingface dataset:
Protein: Casein kinase I homolog 3 (EC 2.7.11.1) (P39962)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus membrane; Lipid-anchor; Cytoplasmic side. Vacuole membrane; Lipid-anchor; Cytoplasmic side. Note=Targeting to the vacuolar membrane may depend on AP-3 pathway.
Interaction partners:
- Vacuolar protein sorting-associated protein 41
- Serine/threonine-protein kinase ENV7
- Ypt/Rab-type GTPase YPT7
- Vacuolar morphogenesis protein 6
- Vacuolar fusion protein MON1
- Syntaxin VAM3
- GTPase-activating protein GYP7
- Vacuolar v-SNARE NYV1
- Vesicular-fusion protein SEC18
- Vacuolar protein sorting-associated protein 33
Sequence:
MSQRSSQHIVGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYLISLMDDALRLNDLKDDGHYDWMDLNGGKGWNIKINRRANLHGYGNPNPRVNGNTARNNVNTNSKTRNTTPVATPKQQAQNSYNKDNSKSRISSNPQSFTKQQHVLKKIEPNSKYIPETHSNLQRPIKSQSQTYDSISHTQNSPFVPYSSSKANPKRSNNEHNLPNHYTNLANKNINYQSQRNYEQENDAYSDDENDTFCSKIYKYCCCCFCCC
Protein: UPF3 domain-containing protein (Q20445)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTDSKDGHVKVVLRRLPKYMTEHEVLEQISPLPEEVIGTYFHPANFSFDRCAYATLTVNFSEYCDSMMEFERRFDGYIFVDSRGNDSAAVVEAASNQNFAKCDRNRMKEDTRVGAILTDKYYLDFCKKLEEERAIPILTLEQQIRKLNQPDDARTQIDKMETPLVKYFFEKETGKRRDYDARRQRRDEKRAEKRDKVDKFEKHKNVLDILMKPSVPMASTSATTSKKDLKKEKPMTEKEKERWEKQDAKRKERNMIRKQKFLDEKKKKHEEREQDGPRVPRDKKKERLAKPPRPSPAKTVGEQQGEDWIKKLTDPKSAPMKKKHDSPPN
Protein: GDNF family receptor alpha 3 (GDNF family receptor alpha-3 precursor) (E7F4G1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Interaction partners:
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Glial cell line-derived neurotrophic factor
Sequence:
MILLGILLNLFVIKGSVSSVVPVFPESVGCLEALQECMMEPECKRQFRHLEYCVDEEAVAPLNLDARQLCVDAQNTLMHYQPLQDCKCQRGSRMEQQCLSIYWTIRFPQGYDDIETSPYEDIELELVRNTETSKLASIVSVSSLPLTDQNQCLKAAQDCGLYEKCGSLRSEYASACTKILPNTNHCNRHKCHRALRRFLERVPEEYSFGVLFCPCSDTLCGERRRKTIVPSCSYEERDGQPNCLHLESYCLKDNLCRSRLADFQQNCQPSSLSPSGCLRDSGAVCLKAYAGLIGTIMTPNYVSNSSTEVSQWCNCEGSGNQWQDCLRILHMFNSNTCLRNAIDNMGSSTPRPVEGTPLPPPRPSPQVQRDELNINLLPEPNAVEESEEVEEEEQEEEEEEEEENQAGGGGFNVIPPFSDKATVTNLGSEAGRVQSSASTCGVPQVLLAVLLLITFRWV
Protein: alpha-1,2-Mannosidase (EC 3.2.1.-) (A0A1D8PD38)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Glucosidase II subunit alpha
- Mannosyl-oligosaccharide glucosidase
Sequence:
MSFSFGINNISKGNNTYKDKPAGGALPLFYKDKVPAFHPAHTSKNKKRILMLLKGFMLSLVLYAVYHLASNGGQFMFDFSGQSKWERAQSEVRQAMLDSWHTYEKYGWGYDVYHPIKQEGEIMGPKPLGWMIVDSLDTLMIMDCPEEVSRARDWIKNDLDYTFDYNVNTFETTIRMLGGLLSAYHFSNDDVYLDKAVQLANALHGAYDSPSGIPYSSVNLKSGKGIKNHVDNGASSTAEAATVQLEMKYLSKLTGEILWWNLAEKVMQVLESNKPQDGLVPIYVNPDTGKYQGHLIRLGSRGDSYYEYLLKQYLQTNKQELVYWDMYRESVEGVKKHLVSDSYPSGLTFIGELDNGIGGKLSTKMDHLVCFYGGLLALGATGGLTLNEAQSLKSWNEEREADFKLGEELTYTCYKMYHDVSPTGLSPEIVVFNEDTSKSKDFIIKPLDRHNLQRPETVESLFYLYRLTGDVKYREMGYEIFQNFIKYTKVVNSEGEVSFSSLSDVTSFDSNGLPKFKDNTESFWWAETLKYLYLLFDDTNKIPLTDYVFNTEAHPFPRFDTNDYFKTGWRRKIDENEKAQMRESKVIDKSNLPEAQPVDKSADQEAKEIIEEIAG
Protein: Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2) (O88923)
Organism: Rattus norvegicus (Rat)
Function: Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Teneurin-2
- Teneurin-4
- Netrin receptor UNC5D
- Teneurin-3
- Netrin receptor UNC5C
- Netrin receptor UNC5A
- Unc-5 family C-terminal like
- Vascular endothelial growth factor A
- Vascular endothelial growth factor B
- SUZ RNA-binding domain-containing
Sequence:
MVSSGCRMRSLWFIMIISFSPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCVVVTGSDVFPDPCPGTYKYLEVQYECVPYMEQKVFVCPGTLKAIVDSPSIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNVIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTVSTTSSTSQRGPVSSTVAGPQEGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALEMKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGTVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAETLDCWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTDNIVLEVAVLSTEGQVQDFTFHLGFKGAFSSIQLSANTVKQNSRNGLAKVVFIIYRSLGPFLSTENATVKLGADLLGRNSTIAVNSHVLSVSINKESSRVYLTDPVLFSMPHIDSDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIVYKDGVHKLLLTVITWVGIVVSLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTQYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDSKSYGTLEACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVNEETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYAKCFRHWYCCGGLPTESPHSSVKASTSRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNTRDTSAMDTLPLNGNFNNSYSLRKADYHDGVQVVDCGLSLNDTAFEKMIISELVHNNLRGSNKTHNLELKLPVKPVIGGSSSEDDAIVADASSLMHGDNPGLEFRHKELEAPLIPQRTHSLLYQPQKKVKPEATDSYVSQLTAEADEHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENEDIYYKSMPNLGAGRQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL
Protein: Nitric oxide synthase oxygenase (EC 1.14.14.47) (NOSoxy-like protein) (Q9RR97)
Organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
Function: Catalyzes the production of nitric oxide. The complex between TrpRS II and nitric oxide synthase oxygenase catalyzes the regioselective nitration of tryptophan at the 4-position.
Interaction partners:
- Arginase
- Ornithine carbamoyltransferase
- Argininosuccinate synthase
- Biosynthetic arginine decarboxylase
- Argininosuccinate lyase
Sequence:
MSCPAAAVLTPDMRAFLRRFHEEMGEPGLPARLRAVEEAGLWWPTSAELTWGAKVAWRNSTRCVGRLYWEALSVRDLRELNTAQAVYEALLQHLDDAFCGGHIRPVISVFGPGVRLHNPQLIRYADDPINADFVDKLRRFGWQPRGERFEVLPLLIEVNGRAELFSLPPQAVQEVAITHPVCLGIGELGLRWHALPVISDMHLDIGGLHLPCAFSGWYVQTEIAARDLADVGRYDQLPAVARALGLDTSRERTLWRDRALVELNVAVLHSFDAAGVKLADHHTVTAHHVRFEEREARAGREVRGKWSWLVPPLSPATTPLWSRRYRAREESPRFVRARCPFHTPTVHASTGHAPTG
Protein: Dynamin-3 (EC 3.6.5.5) (Q8BZ98)
Organism: Mus musculus (Mouse)
Function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Microtubule-associated. {ECO:0000250}.
Interaction partners:
- Dynamin-1
- Dynamin-2
- Src substrate cortactin
- Hematopoietic lineage cell-specific protein
- Actin-related protein 3
- Clathrin heavy chain 1
- Endophilin-A1
- Cyclin-G-associated kinase
- Amphiphysin
- Neural cell adhesion molecule L1
Sequence:
MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRHEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIRDMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAFKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKRLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKSTIGNQVIRKGWLTVSNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKGFMSSKHVFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSVGSNKTENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALAIIGDINTATVSTPAPPPVDDSWLQHSRRSPPPSPTTQRRLTISAPLPRPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPNSSDSFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLESSLLD
Protein: Nucleolar protein 56 (Nucleolar protein 5A) (Q9D6Z1)
Organism: Mus musculus (Mouse)
Function: Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:O00567}. Cytoplasm {ECO:0000269|PubMed:21683323}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:O00567}.
Interaction partners:
- rRNA 2'-O-methyltransferase fibrillarin
- NHP2-like protein 1
- U3 small nucleolar RNA-interacting protein 2
- Nucleolar protein 58
- H/ACA ribonucleoprotein complex subunit DKC1
- WD repeat domain 36
- WD repeat-containing protein 46
- BMS1 homolog, ribosome assembly protein
- WD repeat-containing protein 43
- U3 small nucleolar RNA-associated protein 15 homolog
Sequence:
MVLLHVLFEHAVGYALLALKEVEEISLLLPQVEECVLNLGKFHNVVRLVAFCPFSSSQVALENANAVSEGVVHEDLRLLLETYLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIVNDNATYCRLAQFIGNRRELNEEKLEKLEEITMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAVVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSTPEECEEVNEKSKKKKKLKPQENGMEDPPVSLPKSKKKKAPKEELASDLEEMATSSAKRKKSSPKEEVASEPEEAASPTTPKKKRKFSEEPEVAANFTKSSTKKKKKSQKAQED
Protein: Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like) (Q8WU79)
Organism: Homo sapiens (Human)
Function: GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).
Subcellular location: Cytoplasm. Note=Detected in multiple foci throughout the cytoplasm and in juxtanuclear structures. {ECO:0000250}.
Interaction partners:
- Syntaxin-2
- Phosphatidylinositol-binding clathrin assembly protein
Sequence:
MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSPQMWK
Protein: Mitochondrial carrier protein, putative (Q388T5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLRTLLLHPLYLAISRKRITREAKPPSVFSIIASAYRGEVGGGNNSSKKVRGLRAIYRGVGAAMIGNLIGELVYLHTMEWTKEALDVAFADANVAPERGRDFRTNSFSAAVGGMAGELASLLLVTPIVVVCNRQMTAGYGMSSSNTYGSLRDTLREVSNLYKQPGIGTSWGTARYKLRGLYAGLLPGIMTLPASGVWWALYSRSKAILYTMAEPTLSRWEREMSLVGEKKSPWQQNWLLSPTDNPALNAFAGVVASCVTSFLFNPVDVLHTRMQALPTVSGAVKGAQYTSLRTVVRDLLSAEGWRGLFKGTVANVGASVVGGVVFSSVFELTKLGSDRELWKQI
Protein: Tropomodulin (Q9DEA6)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
EDKILGALTEEELRKLENELEELDPDNALLPAGLRQRDQTQKPPTGPFKREELMAHLEQQAKDIKDREDLVPFTGEKRGKAWIPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYEALGSSTIVNKEGLNSVIKPTKYKPVPDEEPNSTDVEETLKRIQNNDPDLEEVNLNNIMNIPVPTLKACAEALKTNTYVKKFSIVGTRSNDPVAFALAEMLKVNNTLKSLNVESNFISGSGILALVEALQSNTSLIELRIDNQSQPLGNNVEMEIANMLEKNTTLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLAELNGPIFPKCRTGV
Protein: Gamma-tubulin complex component (B3DIU9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
- Gamma-tubulin complex component
- Gamma-tubulin complex component 3 isoform X1
- Mitotic-spindle organizing protein 1
- Gamma-tubulin complex component
- Tubulin gamma chain
- Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper-containing 2.
- NEDD1 gamma-tubulin ring complex targeting factor
- Tubulin delta chain
- Nucleoside diphosphate kinase 7
- Mitotic spindle organizing protein 2B
Sequence:
MIHELLLALSGYPGTIFTWNKRNGLQVSQDLPFLHPSETSVLNRLCKMGTDYVRFTEFIEQHTGHVHQQEHYSSQPSQSGLHGIYLRAFCTGLHSMLQPYRQALLDLEKEFLGDPHLSISHVNYMLEQFQLLFPSVMVVVETIKSQKIHGCQILETVYKHSCGGLPPVRMALEKILAVCHGVMYKQLAAWMLHGLLLDQSEEFFVKQGPSAGGATAAQEEDEEDLGIGGLSGKQLRELQDLRLIEEENMLAPSLQQFSLRVEMLPSYIPVRVAEKILFVGESVQMFENHNQSPSRAGSILKHQEDMFAAELHRLKQQPLFSLVDFENLVDGIRSTVAEHLWTLMVEESDLLGQLKIIKDFFLLGRGELYQVFIDLAQHMLKTPPSAVTEHDVNVAFQQAAHKVLLDDDNLLPLLHLTIDYHGKESKEGSGNREGTTPPQESSPREAPPTGWAALGLAYKVQWPLHILFTPAVLEKYNVVFRYLLSVRRVQSELQHCWALQMQRKHLKSNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLQQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHNFCSLVSQNLGSLDERGTAQLDILVKGFSRQSFLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGL
Protein: Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2) (Q9H2S1)
Organism: Homo sapiens (Human)
Function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:P58390}.
Interaction partners:
- Calmodulin-1
- Calmodulin-1
- Calcium-activated potassium channel subunit alpha-1
- Calcium-activated potassium channel subunit beta-4
- Potassium channel subfamily U member 1
- A-type voltage-gated potassium channel KCND2
- Calcium-activated potassium channel subunit beta-1
- Small conductance calcium-activated potassium channel protein 1
- Small conductance calcium-activated potassium channel protein 3
- Calcium-activated potassium channel subunit beta-3
Sequence:
MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
Protein: Bifocal, isoform F (M9PHA0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus membrane {ECO:0000256|ARBA:ARBA00004232}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004232}. Rough endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004269}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004269}.
Interaction partners:
- Serine/threonine-protein phosphatase alpha-2 isoform
Sequence:
MESQKRPSLDLHTDVPAGLAAGGSGLGAAAEMSPTSGFLPDMPQWKKDLIQRRKTNVARTQAASITSPTDGSCGALAEANAAPGAIADFTEPATISSTSQKRNMIGSEEKSEKSSISNTNSDSTGGHHSVVAVSLSPDAAATTNVTVTPIPKQRSSLLNTRSQEREMVRYILSESGERDGELESGEQPAGVVSNSRCGEVETGTIGSPSSSANQNPNPNHLKTKCKPGQSVAEGKPSAKETIVDNSKSCSKTKSISDKLQSNKFIIQQQQQQQQQQQQQQQLSPTKVTVKPTMVAMQEMKKTTKQNGQHRHLAGKIGSVAGGDVDPQHPPTNPIPDSLDTGEDLSYGPGIVSKLRCRYLSLALRESRQQSSKQRLQRSTSLNTLLDRDDDEVEVEEPEMTNSQVRAKSTPPPILGAKPTPKPSSQHQRPVSLGANGAGSAVNPPSNSDQAQTGAVANGGAGSGQRSRHFKRGNEVMKRARSVEALLCEKSPWNSQRISTAGAAAAAAPSPPAPKATAAAPSPVTSPTCVTIEDKIHNARERLHSGTDTAPPKRLTSIIDDTERPPPDLVKQTLKMFEASANRRPRAAHRSNGVGGVASKVANYKSIIKDQKQPSSAAATPPPTGMGFASSTPLRHVHPDIIPRQVDSPVSALSVMMRRMELQEPETPERETRDAEATPQSEALSETERNDRDEGDGEVDDDNHNNNDDDHDDGDDGSDNNEQRDKMGAAAAGDKPKPPAESAAGGAQRSFAASTENAHVASGSSSSTSASVRKLSNNNDSSSGPAVTKQIGVIRPLFNSQGAGSTPLTSREIEKNRINEMKKSTATDAGGSVSGSGTVAGAGSGTSPTTSLDSVINTKEAASSETDASASPLWTLRKLRNQSQTAGGGSGPSSSLHSTENTSMVFNFSKSTKEVPDYIESDVVIYRRKRELPKPNEPGFVLLGDLSVETSTDTDYDDYSMCPPSPCDVEFENANIVIDGKSSIRQKPKESSFRVQFNDTLTSTFEYPSEASMTIEDPPYADPFGHVSKHHQMLLAEQMHLLQHQEQLELEQMHQLGLAPEQHHHVTVDEIIELPTSTAGHGHGIGLGHRSGAAGGGGTMLGNLPLDYPSLGRGIILPQSPQQQSTQQQEQPEPAIATSATVAGLAVAMATEVEIEPPLPAPPVTVAKRPQLPAKPAQQQQQQAARRARPSVLLKPQYACFLQHDDDAPKSQPTAAGRPRKAASFSLGNQRQSKEQQQHHHHYQPQHQQSKYERNDCSRSRGSCESPAPEHQQRRRRPSLPSSLALSNASSALLQARIPGTTLYYV
Protein: Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor) (Q9NRM6)
Organism: Homo sapiens (Human)
Function: Receptor for the pro-inflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Subcellular location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Interaction partners:
- Interleukin-17B
- Interleukin-17 receptor A
- Interleukin-25
- Interleukin-17C
- Interleukin-17 receptor E
- Interleukin-17 receptor C
- Interleukin-17 receptor D
- Interleukin-17D
- Interleukin-33
- Interleukin-17F
Sequence:
MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
Protein: Knob-associated histidine-rich protein (Q9TY99)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}. Endosome {ECO:0000256|ARBA:ARBA00004177}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004656}.
Interaction partners:
- Erythrocyte membrane protein 3
- Ring-infected erythrocyte surface antigen
- Ring-infected erythrocyte surface antigen
- Mature parasite-infected erythrocyte surface antigen
Sequence:
MKSFKNKNTLRRKKAFPVFTKILLVSFLVWVLKCSNNCNNGNGSGDSFDFRNKRTLAQKQHEHHHHHHHQHQHQHQAPHQAHHHHHHGEVNHQAPQVHQQVHGQDQAHHHHHHHHHQLQPQQPQGTVANPPSNEPVVKTQVFREARPGGGFKAYEEKYESKHYKLKENVVDGKKDCDEKYEAANYAFSEECPYTVNDYSQENGPNIFALRKRFPLGMNDEDEEGKEALAIKDKLPGGLDEYQNQLYGICNETCTTCGPAAIDYVPADAPNGYAYGGSAHDGSHGNLRGHDNKGSEGYGYEAPYNPGFNGAPGSNGMQNYVPPHGAGYSAPYGVPHGAAHGSRYSSFSSVNKYGKHGDEKHHSSKKHEGNDGEGEKKKKSKKHKDHDGEKKKSKKHKDNEDAESVKSKKHKSHDCEKKKSKKHKDNEDAESVKSKKSVKEKGEKHNGKKPCSKKTNEENKNKEKTNNSKSDGSKAHEKKENETKNTAGENKKVDSTSADNKSTNAATPGAKDKTQGGKTDKTGASTNAATNKGQCAAEGATKGATKEASTSKEATKEASTSKEATKEASTSKEATKEASTSKGATKEASTTEGATKGASTTAGSTTGATTGANAVQSKDETADKNAANNGEQVMSRGQAQLQEAGKKKKKRGCCG
Protein: Proton pump-interactor BIP103 (BRI1-interacting protein 103) (Q762B4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May regulate plasma membrane ATPase activity.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O23144}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGMEVVGTEAAPAEVKVTDGEVNLFQENESKATAKEREEAVLFGSDNSTATANGAANGADLAPPKDAEEDWPEARKTHSFFFVKIRLLEDPKLKMKIDQAEKDFQKKIQARSQIFEAIKAKKNERFGIISELKPLAAENKQYNEAVSEKLKAIEPLRNRLGKFRDENNAIRAQGAGICSSIEELEKSIKRLNDRISHESIPLDEEKRLIKQIRELEKTRPKVISTSANRAQIQDTVVERDAIQDQVKIIGEGIDGVKKERQAVRSKIKVLEDELKAIDMEMGSLQEDLTAANARKDKAHESLVQLRHARDAYNASFHQNRQLLSKARDLASRSELAQVQELYKTQVDKFVAEWCNSKAFREDYEKRILSSLNSRQLSRDGRMRNPDEKPIFIETEAAAPPVEQEPIQSKMPAKQAKEAPAPQAEVSPKDESRVKAIAKPSKAKSSLDADDDYEAESPKEKPKPKEVDVAKLKEIKRQEEMEKNRLALERKKKLAEKQAAKAAARAQKEAEKKLKREEMRARRRAGAADTEASTESDNRSDGAAEAQAEDDSAPASAPVMREQRESVRYSRNVVTKSKAPLPKAILRRKKAQSYWSWAGPAAAVAAALVALLAVLGYYQYYLPASASN
Protein: Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (Small stress protein-like protein HSP22) (Q9JK92)
Organism: Mus musculus (Mouse)
Function: Displays temperature-dependent chaperone activity.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9UJY1}. Nucleus {ECO:0000250|UniProtKB:Q9UJY1}. Note=Translocates to nuclear foci during heat shock. {ECO:0000250|UniProtKB:Q9UJY1}.
Interaction partners:
- BAG family molecular chaperone regulator 3
- Heat shock cognate 71 kDa protein
- Heat shock 70 kDa protein 1B
- E3 ubiquitin-protein ligase CHIP
- Heat shock protein beta-1
- Heat shock protein HSP 90-beta
- DnaJ homolog subfamily B member 1
- Heat shock protein beta-2
- Heat shock factor protein 1
- BAG family molecular chaperone regulator 2
Sequence:
MADGQLPFPCSYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTAPWPEWALPRLSSAWPGTLRSGMVPRGPPATARFGVPAEGRSPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPATVFASLSPEGLLIIEAPQVPPYSPFGESSFNNELPQDNQEVTCS
Protein: Chloride intracellular channel exl-1 (Exc-4-like protein) (O45405)
Organism: Caenorhabditis elegans
Function: Probable chloride channel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14684823}. Membrane {ECO:0000269|PubMed:14684823}. Lysosome membrane {ECO:0000269|PubMed:14684823}. Golgi apparatus membrane {ECO:0000269|PubMed:14684823}. Note=Can be translocated to membranes, possibly as integral membrane proteins, with chloride channel activity (By similarity). Localizes to lysosomal membranes in the intestine, and to Golgi apparatus in neurons and muscle. It also localizes to dense bodies, a transmembrane structure which links the muscle cytoskeleton to the neighboring hypodermis. {ECO:0000250}.
Interaction partners:
Sequence:
MPTFSLWLPAGSNNVHPCGDPYAHHLFMRCLYHAKHDPTMKFDVKTTNVNKTSQEFKNTGLRRMPGISAEESGETQTFETEDDILDFLEYLKPERGDDEEAENATCDLFRQFARFVKDVEHRDTAFNTELLRLDKYLSEQETKFLISDDVTHIDCLVLTRLHSIRVAAKMLKNYEIPADLSHVLDYLKAGYATEMFRVSCPSDQEIVLHWTELKDTPRLSAKDRAKLVREEPVFSFSV
Protein: Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit (DHOD B) (DHODase B) (DHOdehase B) (EC 1.3.1.14) (Dihydroorotate oxidase B) (Orotate reductase (NADH)) (P54322)
Organism: Lactococcus lactis subsp. cremoris (strain MG1363)
Function: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor. Cannot use fumarate as an electron acceptor.
Subcellular location: Cytoplasm.
Interaction partners:
- Dihydroorotate dehydrogenase B
- Dihydroorotase
- Orotate phosphoribosyltransferase
- Dihydroorotate dehydrogenase A
- Orotidine 5'-phosphate decarboxylase
- Aspartate carbamoyltransferase catalytic subunit
- Uracil permease
- Carbamoyl phosphate synthase large chain
- Phenylalanine--tRNA ligase beta subunit
Sequence:
MTENNRLSVKLPGLDLKNPIIPASGCFGFGEEYAKYYDLNKLGSIMVKATTLHPRFGNPTPRVAETASGMLNAIGLQNPGLEVIMTEKLPWLNENFPELPIIANVAGSEEADYVAVCAKIGDAANVKAIELNISCPNVKHGGQAFGTDPEVAAALVKACKAVSKVPLYVKLSPNVTDIVPIAKAVEAAGADGLTMINTLMGVRFDLKTRQPILANITGGLSGPAIKPVALKLIHQVAQVVDIPIIGMGGVANAQDVLEMYMAGASAVAVGTANFADPFVCPKIIDKLPELMDQYRIESLESLIQEVKEGKK
Protein: glutathione transferase (EC 2.5.1.18) (B0Y813)
Organism: Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10) (Neosartorya fumigata)
Interaction partners:
Sequence:
MSERPSDLVVNRLVLFVVKGTATSTHNTVKPLILLEELGVPHDIYVVEKVSAPWFSEINPHKMVPAILDRSPDGRDTLRAWESTSTLMYIADAYDKDGTFGGRNVQERSEINNWLTLHTAALGPTAKYWLYFYKLHPEKLPKTIEKLRSNITVQYDILERRLNEPGQQYLALKDRPTIADIATLPFAMKSTAELFGLEFEKWPKLQEWSVRMGEREAVKRAWQRVAGFGHGEKEYGMLEA