wanglab/gogpt-training-data huggingface dataset:
Protein: Bifunctional protein PutA [Includes: Proline dehydrogenase (EC 1.5.5.2) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)] (P09546)
Organism: Escherichia coli (strain K12)
Function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon.
Interaction partners:
- Sodium/proline symporter
- Pyrroline-5-carboxylate reductase
- Glutamate 5-kinase
- Gamma-glutamyl phosphate reductase
- Glutamine synthetase
- NADP-specific glutamate dehydrogenase
- Glutamate synthase large chain
- Glutaminase 1
- Glutaminase 2
- Glutamate synthase small chain
Sequence:
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAKYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGTIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
Protein: Gamma-aminobutyric acid receptor subunit rho-3 (GABA(A) receptor subunit rho-3) (GABAAR subunit rho-3) (GABA(C) receptor) (A8MPY1)
Organism: Homo sapiens (Human)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular location: Postsynaptic cell membrane; Multi-pass membrane protein {ECO:0000255}. Cell membrane; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit rho-1
- Gamma-aminobutyric acid receptor subunit rho-2
Sequence:
MVLAFQLVSFTYIWIILKPNVCAASNIKMTHQRCSSSMKQTCKQETRMKKDDSTKARPQKYEQLLHIEDNDFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSMTFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYSSTGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYLTTVEERKQFKKTGKISRMYNIDAVQAMAFDGCYHDSEIDMDQTSLSLNSEDFMRRKSICSPSTDSSRIKRRKSLGGHVGRIILENNHVIDTYSRILFPIVYILFNLFYWGVYV
Protein: B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a) (P11911)
Organism: Mus musculus (Mouse)
Function: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10587346, ECO:0000269|PubMed:11238609, ECO:0000269|PubMed:15661879}; Single-pass type I membrane protein {ECO:0000269|PubMed:10587346, ECO:0000269|PubMed:11238609, ECO:0000269|PubMed:15661879}. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Interaction partners:
- B-cell antigen receptor complex-associated protein beta chain
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase Lyn
- Immunoglobulin lambda-like polypeptide 1
- B-cell linker protein
- B-lymphocyte antigen CD19
- C-X-C motif chemokine 9
- B-cell receptor CD22
- Tyrosine-protein kinase BTK
- B-lymphocyte antigen CD20
Sequence:
MPGGLEALRALPLLLFLSYACLGPGCQALRVEGGPPSLTVNLGEEARLTCENNGRNPNITWWFSLQSNITWPPVPLGPGQGTTGQLFFPEVNKNHRGLYWCQVIENNILKRSCGTYLRVRNPVPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKFGVDMPDDYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGNLHIGDAQLEKP
Protein: Vacuolar protein sorting-associated protein 35 (Q21053)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
- Vacuolar protein sorting-associated protein 26
- PX domain-containing protein
- Vacuolar protein sorting-associated protein 29
- Sorting nexin-3
- PX domain-containing protein
- Sorting nexin-27
- E3 ubiquitin-protein ligase parkin
- Serine/threonine-protein kinase pink-1, mitochondrial
- Endocytosis protein RME-8
- Ras-related protein Rab-7a
Sequence:
MYENSGNTTDQEKFLDQSIRVVKAESFEMKRCLDKGKTMDALKHALQMLNEMRTAELSPKFYYRLYMDSMHELQCLEVNLVQEYAQEPAKLGNLYECVQYASAIIPRLYLLVTIGGVFIKCGLGSRKEILKDLVEMCRGVQHPLRGLFLRNYLMQCTRSVLPDFPETEEMLVAHNDNLSKGTPKLKPRDGTVDDTIDFVLINFAEMNKLWVRMQHQGPSKEKEKREKDRMELRILVGTNLVRLAQLEALTEEMYVKDVLPSILEQIVSCRDPISQEYLMECVIQVFADDFHLATLTEFLNACGQLQQDVNIKILLIALVDRLALYTTSYNEGQPAPTKMQLFEIFSEQATTLIKNRPDMPLDDIVALHVSLVSLAVKCYPDRQDYANMTFQGLRQVIEEKGVTDIEAFGKVGRELTKLLNIPIDEYKNVLRLSQLPEYIKVMNYFDYRGQCNIASYMIQNMLEEETVFRNQDDVDSAFSLISSLLKDQEKQSSDSHETEEFADEQNLVARLLHLIRADDVDSQFLLLNSARKTLGEGGRHRLRYTLPPIIFELYRLVLQFSDMKDEDDKWDAKIRKMFVCAMGTIGALVSTAELAELPMKLYLNGAITADRVPFEDNHTVVYEFVSKALSILEDDVVDSRDRVRCLHLTVGTLLKTTHLPEENWQPLANQTVLAAAKMFKKPDQVRSLVTVAALYWHGQTLETNGEKMKNGKKVVDILRKAAKIARECLEPLVQQQLFIQLLSAYTYYYEDNCSEVNVDHIEELIARTQDNAVQLDVSAEADSLEKQLGEAIRRLQLAKLDVAAAQATTIRSEPELPQPPS
Protein: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] (Q60967)
Organism: Mus musculus (Mouse)
Function: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Required for normal biosynthesis of sulfated L-selectin ligands in endothelial cells (By similarity).
Interaction partners:
- FAD synthase
- Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase
- 3'
- Sulfite oxidase, mitochondrial
- Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- Elongation factor 1-alpha 1
- Elongation factor 1-alpha 2
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3B
- HBS1-like protein
Sequence:
MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVPENKLHLAKTDAEALPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALVYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVLEQGDWLIGGDLQVLDRIYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGILDPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPTHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLVEYYKSLEKA
Protein: Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) (F1NZI4)
Organism: Gallus gallus (Chicken)
Function: Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
Interaction partners:
- Pseudouridine-5'-phosphatase
- Epimerase_2 domain-containing protein.
- Aldose 1-epimerase
- Mannosyl-oligosaccharide glucosidase.
- Protein YIPF.
- Interferon induced transmembrane protein 5
- Interferon induced transmembrane protein 10
- Interferon-induced transmembrane protein 3
- Mitochondrial import inner membrane translocase subunit
Sequence:
MSMRGSGKLWLVMADGQEDPAVFTSTCLPSDSRLLATVTNAYLGTRVYRNILHVSGVYNGAAGDTHRADIPSPVNVRMTVPDGDVPVETFTLNTRTGTFSHKLESSSYTATHQIYAHHSLVHLMAFSITIWRSAGTSQPITVQLQAPFVPKSQDLDLQQGPDFQGAHYIYGQTLVPEVEGGPQPTVHMLWTPVPQAVTLHEEEQERRWEFLTAVAESEEEAKRSYSEGLARMAAGSLHSSHTRAWAALWRGCCVDLEGPLPLRQALYGCLYYLLSAIPPQGTPGFHFHGISPGGLSNGTRGEDYWGHVFWDQDTWIFPNILLFYPEAARAILEYRIRTLEGALLNAQEQGYKGAKFPWESAATGREVCPEDIYGAQEIHITGDVLMAFEQYYHTTQDQKLFRTDGGWELVSAVAQYWCSRMVWSEEEQCYHIRGVMPPDEYHYQVDNSAYTNAVAQRSLNFAASVARDFFIPVPEEWVECAKKVKVPFDAVRKYHPEYDGYSPGEPVKQADVVLLGFPLMHPMHPEVRRNDLVMYEPVTELSGPAMTWSMFAVGWLELKETQRAQGLLNKCFSNITEPFKIWVENSDGSGAVNFLTGMGGFLQAVLFGYTGFRITKTNLRFDPAFPSDVSKLEVTGVSYLGSKLKFSITKEKMRIAVTKCPLHPPLEAVLEESGQRFPLHEGQSISFPTAAGCIQKAPSEGL
Protein: Dachshund, isoform F (Q59DY9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHGMPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPERPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGPLGIDAHAAVPASSTETLLRNIQSLLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNTKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN
Protein: Galactinol synthase 1 (ArGolS1) (GolS-1) (EC 2.4.1.123) (Q9XGN4)
Organism: Ajuga reptans (Bugle)
Function: Major galactinol synthase mainly involved in the biosynthesis of storage raffinose family oligosaccharides (RFOs) that function as osmoprotectants. May promote plant stress tolerance.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
Sequence:
MGPVVPVEAFRSAGKISALGAKKGYVTFLAGNGDYVKGVVGLAKGLRKVKSAYPLVVAILPDVPEEHRELLRSQGCIVKEIEPIYPPANQIQFAMAYYVINYSKLRIWNFEEYSKMVYLDADIQVYENIDHLLDTPDGYFYAVMDCFCEKTWSHSRQFSIGYCQQCPNKVTWPAQMGSPPPLYFNAGMFVFEPSKTTYQTLLHTLRITPPTPFAEQDFLNMFFEPIYKPIPLVYNLVLAMLWRHPENVELEKVQVVHYCAAGSKPWRYTGQEANMDREDIKMLVKKWWDVYNDESLDFKAEDSIAGEETFSMPSFIASLPEPAVSYIPAPSAA
Protein: ATP synthase subunit beta (EC 7.1.2.2) (Q8T4C4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- ATP synthase subunit gamma, mitochondrial
- ATP synthase subunit alpha, mitochondrial
- ATP synthase F
- ATP synthase subunit a
- ATP synthase subunit b, mitochondrial
- FI05611p
- ATP synthase subunit d, mitochondrial
- ATP synthase subunit b
- ATP synthase subunit O, mitochondrial
- ATPase protein 9
Sequence:
MLVSWAKMATACARIGLKMGPGTGGYRGNYLGNPVVFPRYLHASLSLWDDKDKKKSGDECEPEPQEVCKTDAELVKKKDEAEDECEEKKSDGGGKKLESKGRKGVIHAVIGPVIDVYFEEEVPEVLNALQVQDAPIANLVLEVFHHLGNNIVRCVAMDSTEGLRRGQPVLDTGYPIRVAVGKAVLGRILNVVGDPIDDRGEVKSDFYSFIHNEAPELTDLSVKPEILVTGIKVIDLLAPYVKGGKIGLFGGAGVGKTVLIMELINNIAKSHGGYSVFVGAGERTREGNDLYHEMIESKVISLEDDSSKVVLVFGQMNEPPGARSRVVLTGLTIAEYFRDVDGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLGTDMGTMQERITSTRNGSITSVQAVYVPADDLSDPAPAATFSHLDATTVLSRPIAELGIYPAVDPLDSSSRILDPDVVGEEHYNVARAVQKTLQAYKSLQDIIAILGMDELSEEDKLTVARARKMQRFLSQPFQVAEIFTGHPGKLVPVEKCVEGFKRLLNGEYDDIPEIAFYMVGDAEEVLAKATQLAASMSGDAPPAKAEAKKDEKKDTKPEEGKKEEPPKGEDKKEEAKDDKPKEPEKKD
Protein: Phosphatidylinositol-glycan biosynthesis class X protein (PIG-X) (Q8TBF5)
Organism: Homo sapiens (Human)
Function: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- GPI alpha-1,4-mannosyltransferase I, catalytic subunit
Sequence:
MAARVAAVRAAAWLLLGAATGLTRGPAAAFTAARSDAGIRAMCSEIILRQEVLKDGFHRDLLIKVKFGESIEDLHTCRLLIKQDIPAGLYVDPYELASLRERNITEAVMVSENFDIEAPNYLSKESEVLIYARRDSQCIDCFQAFLPVHCRYHRPHSEDGEASIVVNNPDLLMFCDQEFPILKCWAHSEVAAPCALENEDICQWNKMKYKSVYKNVILQVPVGLTVHTSLVCSVTLLITILCSTLILVAVFKYGHFSL
Protein: Proton channel OTOP1 (Otopetrin-1) (hOtop1) (Q7RTM1)
Organism: Homo sapiens (Human)
Function: Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage (By similarity). Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration (By similarity). Probably acts by maintaining the pH appropriate for formation of otoconia (By similarity). Regulates purinergic control of intracellular calcium in vestibular supporting cells (By similarity). May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol (By similarity). Also involved in energy metabolism, by reducing adipose tissue inflammation and protecting from obesity-induced metabolic dysfunction (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:36266567}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q7ZWK8}. Cell projection, microvillus {ECO:0000250|UniProtKB:Q80VM9}. Note=Found in the gelatinous membrane overlying the inner ear macular epithelium. Also detected in the apical microvilli in inner ear supporting cells. {ECO:0000250|UniProtKB:Q80VM9}.
Interaction partners:
- Otoconin-90
- Plasma membrane calcium-transporting ATPase 2
- Polycystin-2-like protein 1
- Plasma membrane calcium-transporting ATPase 4
Sequence:
MLEGLGSPASPRAAASASVAGSSGPAACSPPSSSAPRSPESPAPRRGGVRASVPQKLAEMLSSQYGLIVFVAGLLLLLAWAVHAAGVSKSDLLCFLTALMLLQLLWMLWYVGRSSAHRRLFRLKDTHAGAGWLRGSITLFAVITVILGCLKIGYFIGFSECLSATEGVFPVTHSVHTLLQVYFLWGHAKDIIQSFKTLERFGVIHSVFTNLLLWANGVLNESKHQLNEHKERLITLGFGNITTVLDDHTPQCNCTPPTLCTAISHGIYYLYPFNIEYQILASTMLYVLWKNIGRKVDSHQHQKMQFKSDGVMVGAVLGLTVLAATIAVVVVYLIHIGRSKTKSESALIMFYLYAITLLMLMGAAGLAGIRIYRIDEKSLDESKNPARKLDSDLLVGTASGSWLISWGSILAILCAEGHPRYTWYNLPYSILAIVEKYIQNLFIFESIHREPEKLSEDIQTLRVVTVCNGNTMPLASSCPKSGGVARDVAPQGKDMPPAANGNVCMRESHDKEEEKQEESSWGGSPSPVRLPRFLQGNAKRKVLRNIAAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI
Protein: Complement inhibitory factor H (Q91YB6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MRLSARIIWLILWTVCVAEDCKGPPPRENSEILSGSWSEQLYSEGTQATYKCRPGYRTLGTIVKVCKNGEWVPSNPSRICRKRPCGHPGDTPFGSFRLAVGSEFEFGAKVVYTCDEGYQLLGEIDYRECDADGWTNDIPICEVVKCLPVTELENGRIVSGAAEPDQEYYFGQVVRFECNSGFKIEGQKEMHCSENGLWSNEKPQCVEISCLPPRVENGDGIYLKPVYKENERFQYKCKQGFVYKERGDAVCTGSGWNPQPSCEEMTCLTPYIPNGIYTPHRIKHRIDDEIRYECKNGLYPATRSPVSKCTITGWIPAPRCSLKPCDFPQFKHGRLYYEESRRPYFPVPIGKEYSYYCDNGFTTPSQSYWDYLRCTVNGWEPEVPCLRQCIFHYVEYGESLYWQRRYIEGQSAKVQCHSGYSLPNGQDTILCTENGWSPPPKCVRIKTCSVSDIEIENGFFSESDYTYALNRKTRYRCKQGYVTNTGEISGIITCLQDGWSPRPSCIKSCDMPVFENAMTKNNNTWFKLNDKLDYECHIGYENEYKHTKGSITCTYDGWSSTPSCYERECSIPLLHQDLVVFPREVKYKVGDSLSFSCRSGHRVGADLVQCYHFGWSPNFPTCEGQVKSCDQPLEIPNGEIKGTKKVEYSHGDVVEYDCKPRFLLKGPNKIQCVDGKWTTLPICVEYERTCGDLPELEHGSVKLSVPPYHHGDSVEFTCTETFTMIGHAVVFCISGRWTELPQCVATDQLEKCKAPKSTGIDAIHPNKNEFNHNFSVSYRCRQKQEYEHSICINGRWDPEPNCTRNEKRFCPPPPQIPNAQVIETTVKYLDGEKVSVLCQDGYLTQGPEEMVCKHGRWQSLPRCTEKIPCSQPPKIEHGSIKSPRSSEERDLIESSSYEHGTTFSYVCDDGFRISEENRVTCNMGKWSSLPRCVGIPCGPPPSIPLGIVSHELESYQYGEEVTYNCSEGFGIDGPAFIKCVGGQWSEPPKCIKTDCDNLPTFEIAKPTEKKKKSYRSGEQVTFRCPPPYRMDGSDIVTCVNTKWIGQPVCKDNSCVNPPHVPNATILTRHKTKYPSGDKVRYDCNKPFELFWGSGSDVPKTGFWTEPPKCKDSTGKCGPPPPIDNGDITSLSLPVYAPLSSVEYQCQNYYLLKGNKIVTCRNGKWSQPPTCLHACVIPEDIMEKHNIVLRWRENAKIYSQSGENIEFMCKPGYRKFRGSPPFRTKCIEGHINYPTCV
Protein: Serine/threonine-protein kinase Nek6 (EC 2.7.11.34) (NimA-related protein kinase 6) (AtNek6) (Q9LT35)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in plant development processes.
Interaction partners:
- Kinesin-like protein KIN-14C
- Serine carboxypeptidase-like 41
- Nematode resistance protein-like HSPRO1
- Tubulin alpha-4 chain
- Protein salt-induced and EIN3/EIL1-dependent 1
- Non-canonical heme oxygenase HOZ, chloroplastic
- Serine carboxypeptidase-like 14
Sequence:
MDDYEVVEQIGRGAFGSAFLVIHKSERRKYVVKKIRLAKQTERCKLAAIQEMSLISKLKSPYIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAIDYLHNNRVLHRDLKCSNIFLTKENEVRLGDFGLAKLLGKDDLASSMVGTPNYMCPELLADIPYGYKSDIWSLGCCMFEVAAHQPAFKAPDMAALINKINRSSLSPLPVMYSSSLKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQNLSPVFKPVVSKSEHNTNENRTGLPPKTKSAKTPIKHNQESEETEKKNKDTSSSSKDKERPAKSQEMSVISTLTLLREFQKKSPKSEERAEALESLLELCAGLLRQEKFDELEGVLKPFGDETVSSRETAIWLTKSLMNVKRKQNDDETNI
Protein: DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD) (O54786)
Organism: Mus musculus (Mouse)
Function: Inhibitor of the caspase-activated DNase (DFF40).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- DNA fragmentation factor subunit beta
- Caspase-3
- Granzyme B
Sequence:
MELSRGASAPDPDDVRPLKPCLLRRNHSRDQHGVAASSLEELRSKACELLAIDKSLTPITLVLAEDGTIVDDDDYFLCLPSNTKFVALACNEKWIYNDSDGGTAWVSQESFEADEPDSRAGVKWKNVARQLKEDLSSIILLSEEDLQALIDIPCAELAQELCQSCATVQGLQSTLQQVLDQREEARQSKQLLELYLQALEKEGNILSNQKESKAALSEELDAVDTGVGREMASEVLLRSQILTTLKEKPAPELSLSSQDLESVSKEDPKALAVALSWDIRKAETVQQACTTELALRLQQVQSLHSLRNLSARRSPLPGEPQRPKRAKRDSS
Protein: Trafficking protein particle complex subunit 11 (Q8IG85)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Golgi apparatus, cis-Golgi network {ECO:0000256|ARBA:ARBA00004222}.
Interaction partners:
Sequence:
KPKRASYEWYHPKGILKRNWMLKHLHVLPSVVVLFQDMEWNDLQWTEKQVQCAAIVQALKNALQERNTRLCLVLLQRAAPLPPGEDLLAAERAASLTNACGITSKMLFILPHTEHLTGYALRLESAFLDMAQSYYALMSKRIRNHRDQLTSAHTSLKIRHQFKLGFVAEMRQDFSTGQKHYFQAYANLDEIRINDGNCLEIKTLAGFLNYKICRLMFKLKTPRDAINQFIIHVEKHKSRVGFKDLAFEHHAWLSTQHSVFAELFCEAIKNGLPALQTQHPGIYYHKAAEFVMKRRDAAMEAYAAMQASSEATPTPIQNPLSLYTEFFGIRAVKTGDLVAEQQANMQLCDQERSYNHSAAIIALLSQAMAQFKIYKCLRFRKKLAIDMAEEYLKSGDHAKALTLYSLMLPDYRQEKWTTIFTDVLLKTLRCALLSGSVADYIACSVEALSLRHQSDQSERILILENLWQVFQGVPPMPKTQLTPEAQALWTSALANVKSPIQIDLDKVNDVVEMCATFERVQLSNDDLLQLQLIVRVLTDIPLRIRSFHVILADAGNPQNSYKLEALKYFCFPTLTQLRGQKQPDNEQLENQSQEPKNFEKNMRLEPGSYYQLFCSTEAQQFHENTQLRIVRLEAHMGTDQVAALLTCSSNYSRQLFRHHTRSRDLDDNVTINPICYIAPTFHLDTQTNLGHGHDNGLTDDKEMVATKMLVNEYFPVVTTVSNPYNVYLQNVGVHISIPVGLRNSVFLTTDISPGRQKLHSQIQIDVGELSAHGSNTATFYIFSLTEAEIKLAQRLSYTLDVDRGPGGGGSNARVSTAPNSSESTPDHEVKSVIPSVAAISPVQIEYLDETRLRKSREDTLTVRCYGDFKFNARFYTMDRKPLNQVYRGENFLLRANTEVVAVDDVEILDSFFICDHNLVQSNYSFKQKKYTNKYSAGEQLESVIVLRTNATLRDWATARDLDHRGKLEGKAVASKFIRPVPKPSSEEPLAPTPPAGISAYMSKSLVTKIPTTMTIINSNSAVSNALQVANAGVMSNSTQSDDVNVAEEAINTQEGIKTTRLIYNKALEAVQGTGHCRGFIKKIYTLEGNPSAVPIFGVFCIRWRRANCKEENESKFVIRGLDIAEPPLNIYCTIEEKMFVKMPMAFKVVLKNPTTHVLHLIANLSISKTDNFICSGHKQLDISIMAYEEKELVYNLYPLQVGWQELPVLSLEYNTKADPQKKDSQNALLDELVQRALPKRVFVLPPLKQQNK
Protein: Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1) (Q24143)
Organism: Drosophila melanogaster (Fruit fly)
Function: Binds selectively to the HSP27 20E response element.
Subcellular location: Nucleus.
Interaction partners:
- Protein ultraspiracle
- Ecdysone-induced protein 75B, isoform B
- Taiman, isoform G
- Lipase
- Mediator of RNA polymerase II transcription subunit 1
- Estrogen-related receptor splice variant
- Transcription factor HNF-4 homolog
Sequence:
MSPPKNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIGMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDKEPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANSPDFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTYGGCNSAANNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLASEALYDPVDEDLSALMMGDDRIKPDDTRHNPKLLQLINLTAVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEMMIMRSVMIYDDDRAAWKVPHTKENMGNIRTDLLKFAEGNIYEEHQKFITTFDEKWRMDENIILIMCAIVLFTSARSRVIHKDVIRLEQNSYYYLLRRYLESVYSGCEARNAFIKLIQKISDVERLNKFIINVYLNVNPSQVEPLLREIFDLKNH
Protein: Phosphoenolpyruvate carboxylase (PEPC) (PEPCase) (EC 4.1.1.31) (Q4JCJ1)
Organism: Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Function: Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Interaction partners:
- Malate dehydrogenase
- Phosphoenolpyruvate synthase
- Phosphoenolpyruvate carboxykinase
- Enolase
- Pyruvate kinase
- Citrate synthase
- malate synthase
- Formate dehydrogenase alpha chain
- Conserved protein
Sequence:
MRKIPRTMSTQHPDNAKVPEWNQGEAISGENEIIEAYLAFSRYGVEEVMWDAEGKDVDTHVVRKLLSQYPEFFRHRILGKDIFLTYRVPNPKIEGAERKVFAETLNTIPITYDLAEKFYGENPNPPVFEVILPFTTSYEELIAVIKFYEKVIVNSDNTKLVDDTYVKDIIGETNPKKIEVIPLIEDRDSMLRIDTIVGKYIEIERPPYLRVFLARSDPAMNYGLLSAVLSVKYALSRLSKMEKIYGVKIFPLLGVGSLPFRGHFSPYNVENTLNEYRGIYTFTVQSAFKYDYEDDLVISAIKKVNGTNVTEKIELSEEDEEIISNVTRKYTQGYQNKIEALADVINKVALLLPRRRARKLHIGLFGYSRSTGKVTLPRAISFVGSLYTIGIPPEIIGLSSLSKMTDQELNAIFNNYKYLKNDLQFAARFVNFEALQLLKDIWNIDAEVVKAIKEDIDYAENSLGIRIGESDYMSKKHVLLSTLALLSIKEGKLDEAKTYIKEMAIVRRAIG