wanglab/gogpt-training-data huggingface dataset:
Protein: Gamma-aminobutyric acid receptor subunit alpha-4 (GABA(A) receptor subunit alpha-4) (GABAAR subunit alpha-4) (Q9D6F4)
Organism: Mus musculus (Mouse)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17005728}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P48169}. Postsynaptic cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P48169}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit beta-1
- Gamma-aminobutyric acid receptor subunit delta
- Vesicle-fusing ATPase
- Gamma-aminobutyric acid receptor subunit beta-3
- Inactive phospholipase C-like protein 1
- Huntingtin-associated protein 1
- Trafficking protein, kinesin binding 2
- Gamma-aminobutyric acid receptor subunit gamma-1
- Gamma-aminobutyric acid receptor-associated protein
- Gamma-aminobutyric acid receptor subunit gamma-2
Sequence:
MVSVQKVPAIALCSGVSLALLHFLCLAACLNESPGQNSKDEKLCPENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKPPPEVPAAPVLKEKHTETSLQNTHANLNMRKRTNALVHSESDVKSRTEVGNHSSKTSAVQESSEATPKAHLASSPNPFSRANAAETMSAAARGLSSAASPSPHGTLRPASLGSASTRPAFGSRLGRIKTTVNTTGAAGNVSATPPPPAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKSESLM
Protein: JAZF zinc finger 1 (C9JGY8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDILSLLMFGIPLKNTDPRVLEKQELQQPTYVALSYINRFMTDAARREQESLKKKIQPKLSLTLSSSVSRGNVSTPPRHSSGSLTPPVTPPITPSSSFRSSTPTGSEYDEEEVDYEESDSDESWTTESAISSEAILSSMCMNGGEEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVR
Protein: Roundabout1 protein (Q90Z42)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
HFYLCGLLCLASGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPLDDKDERITIRGGKLMITYTRKNDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKARYEIRDDHTLKIRKVMAGDMGSYTCVAENMVGKAEASATLTVQVVSEPPQFVVKPRDQVAALGRTVTFQC
Protein: Anaphase-promoting complex subunit 5 (20S cyclosome/APC complex protein apc5) (Q9P4W7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.
Interaction partners:
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 1
- Anaphase-promoting complex subunit 10
- Mitotic spindle checkpoint component mad3
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 8
- Anaphase-promoting complex subunit 3
- Anaphase-promoting complex subunit cut9
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 14
Sequence:
MQSPAMSMVTPIFPIPLKTNSSKKNFYTTFLTPHKLTLCLLIELYAHRIIQPQHCVPFLDLVLGYFNPNDSQPQTLTRIHDITSHLPSSIEEYSVYSLLHERLWSLHSFEDIHEIFISLGNYIEGVYDSEEEAPHMLFSSSSLLSIFLRKCVVEYEQFSFEQGVQFFKSFLQYRAPSMDFQHEGIEFCKINVRHELMNLASNKTLLQLAFGSIPVSRSSRDIEQLTQVQIEHMQKFGCALPLEMKEKLHDLLEVEENNLNTSYYCKFLNSWFSGDYQQSVENLCRYFDHIMHSDEKVSYQYALLNLAMLQADFGCNEEALHAIEDTINTARESGDTACLNFALAWMFEFKRSQYSNPSPEKNENDDQILEHLARNSQKAQLPILQTTVHLLQVQKFLDDGSSLIGVFSNLTKAFALFCANESFDGFPRYMDLLQSIWYRLGCSILSMTYISIYQKNHVHDSPALDLLQSLITKAWRYAELGRWLDVATILSTAEVQSQRSFQCAHLYGREKTFIYLSKAIDEKNHMDATLYLKNLNGFRHDKMSTFRTQLYALRLDISLGNLSQAIEGIDKLLEEPEKLAIEWVLQLMFLKVDIYMRTEMSNRAVFELLEIIQMASSNYLRLYLLRGLCTLCLIGELDCFTAIDLLDSLIPDIIAADNKPLLALAFHAFASLQIKHLDLLQPSRMFVIQLLDSAIDGYRACYMVEMQKTVVRLKIQYLRQINDPALQPNIEQYCSRFYSDNLLN
Protein: Transferrin-binding protein B (TbpB) (TbpB receptor) (Transferrin-binding protein 2) (TBP-2) (Q09057)
Organism: Neisseria meningitidis serogroup B
Function: Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Involved in the initial capture of TF. Helps select only those TF molecules that can be used as an iron source and concentrates them on the cell surface, maintaining the iron-loaded status of the TF C-terminal lobe until its delivery to TbpA.
Subcellular location: Cell outer membrane {ECO:0000305|PubMed:8344530}; Lipid-anchor {ECO:0000305|PubMed:8344530}. Cell surface {ECO:0000269|PubMed:8344530, ECO:0000305|PubMed:22343719}.
Interaction partners:
Sequence:
MNNPLVNQAAMVLPVFLLSACLGGGGSFDLDSVDTEAPRPAPKYQDVSSEKPQAQKDQGGYGFAMRLKRRNWYPGAEESEVKLNESDWEATGLPTKPKELPKRQKSVIEKVETDGDSDIYSSPYLTPSNHQNGSAGNGVNQPKNQATGHENFQYVYSGWFYKHAASEKDFSNKKIKSGDDGYIFYHGEKPSRQLPASGKVIYKGVWHFVTDTKKGQDFREIIQPSKKQGDRYSGFSGDGSEEYSNKNESTLKDDHEGYGFTSNLEVDFGNKKLTGKLIRNNASLNNNTNNDKHTTQYYSLDAQITGNRFNGTATATDKKENETKLHPFVSDSSSLSGGFFGPQGEELGFRFLSDDQKVAVVGSAKTKDKLENGAAASGSTGAAASGGAAGTSSENSKLTTVLDAVELTLNDKKIKNLDNFSNAAQLVVDGIMIPLLPKDSESGNTQADKGKNGGTEFTRKFEHTPESDKKDAQAGTQTNGAQTASNTAGDTNGKTKTYEVEVCCSNLNYLKYGMLTRKNSKSAMQAGGNSSQADAKTEQVEQSMFLQGERTDEKEIPTDQNVVYRGSWYGHIANGTSWSGNASDKEGGNRAEFTVNFADKKITGKLTAENRQAQTFTIEGMIQGNGFEGTAKTAESGFDLDQKNTTRTPKAYITDAKVKGGFYGPKAEELGGWFAYPGDKQTEKATATSSDGNSASSATVVFGAKRQQPVQ
Protein: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit) (P17694)
Organism: Bos taurus (Bovine)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I (By similarity). Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction (By similarity). Plays an important role in carotid body sensing of hypoxia (By similarity). Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:10852722, ECO:0000269|PubMed:18721790, ECO:0000269|PubMed:25209663}; Peripheral membrane protein {ECO:0000305|PubMed:25209663}; Matrix side {ECO:0000305|PubMed:25209663}.
Interaction partners:
- Cytochrome b-c1 complex subunit 1, mitochondrial
- NADH-ubiquinone oxidoreductase chain 2
- NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial
- Acyl carrier protein, mitochondrial
- NADH dehydrogenase 1 subunit C2
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- NADH-ubiquinone oxidoreductase chain 4L
Sequence:
MAALRALCRLRGAAAQVLRPGAGVRLPIQPSRGARQWQPDVEWAEQYGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYVRPGGVHQDLPLGLMDDIYEFSKNFSLRIDELEEMLTNNRIWRNRTVDIGIVTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSIRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
Protein: Neuropeptides capa receptor (Cap2b receptor) (Capability receptor) (Q8ITC7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as a receptor for the neuropeptides CAP-1 and CAP-2, but not CAP-3. Probably a component of signal transduction pathway that leads to Malpighian tubule fluid secretion in response to these ligands.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cardio acceleratory peptide 2b
Sequence:
MNSSTDPTFSELNASFTNTPDTLFATSVSSDPSHGFGEEDYACGTFNCSPKEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRVAFRELLCGKAVGAYYNSGFARDHSSFRESSAYDRVHSVHVRASQHPNKFETDSSSANRVLIKKTYSLPLPKNADSTVLSTTDIVIVLENSHTVCEEPKVENDIWIENEETCI
Protein: Leucine-rich repeat and fibronectin type-III domain-containing protein 2 (Synaptic adhesion-like molecule 1) (Q9ULH4)
Organism: Homo sapiens (Human)
Function: Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein. Synapse. Postsynaptic cell membrane {ECO:0000250}.
Interaction partners:
- Disks large homolog 4
- Disks large homolog 3
- Disks large homolog 1
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2A
Sequence:
METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRAPWRIPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV
Protein: Surface presentation of antigens protein SpaN (Spa32 protein) (P0A1K5)
Organism: Shigella flexneri
Function: Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of IpaB and IpaD proteins.
Subcellular location: Secreted {ECO:0000269|PubMed:11115111, ECO:0000269|PubMed:1312536}. Cell outer membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Secreted via the Mxi-Spa type III secretion system (T3SS).
Interaction partners:
Sequence:
MALDNINLNFSSDKQIEKCEKLSSIDNIDSLVLKKKRKVEIPEYSLIASNYFTIDKHFEHKHDKGEIYSGIKNAFELRNERATYSDIPESMAIKENILIPDQDIKAREKINIGDMRGIFSYNKSGNADKNFERSHTSSVNPDNLLESDNRNGQIGLKNHSLSIDKNIADIISLLNGSVAKSFELPVMNKNTADITPSMSLQEKSIVENDKNVFQKNSEMTYHFKQWGAGHSVSISVESGSFVLKPSDQFVGNKLDLILKQDAEGNYRFDSSQHNKGNKNNSTGYNEQSEEEC
Protein: Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) (Q761V0)
Organism: Mus musculus (Mouse)
Function: Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9Y345}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glycine receptor subunit alpha-1
- Glycine receptor subunit beta
- Vesicular inhibitory amino acid transporter
- Vesicular glutamate transporter 2
- Glutamate decarboxylase 1
- Glycine--tRNA ligase
Sequence:
MDCSAPKEMNKQPANILEAAVPGHRDSPRAPRTSPEQDLPAEAPAATVQPPRVPRSASTGAQTFQSADARACEAQQSGVGFCNLSSPRAQATSAALRDLSEGHSAQANPPSGPAGAGNALHCKIPALRGPEEDANVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC
Protein: T-box transcription factor 2a (T-box transcription factor TBX2a) (B0R122)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Iroquois homeobox 3b.
Sequence:
MRDPVFTANAMAYHPFHAHRPADFPMSAFLAAAQPSFFPALTLPPGLSKPLADHALSGAAEAGLHAALGHHHQAAHLRSFKGLEPEEDVEDDPKVTLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVNGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLAMPSMRMYDDQCKVDRDGGDSDDSSCEQTTGRDSVHSPTGPATSPLKFTRSREDKNFNESDNELDQHDDGMIRVSSPEQRPQSPFSPRCEDRVKDRLNLEKKGDYSDSRKENDSAFSIRHLDKDKLDARNVKDQDSSKKEADSVGMSTVKDGFSPLMVQTENPSHFSASHLQSLALSGLHNQHFFNPLSSGQSLLFHPGQFAMTPSAFSTMGMGHLLASMSGASGLENGSLSSQSTSSPNPFPFHLSQHMLASQGISMPTFGGLLPYPYTYMAAAAAAASALPAGSAASSLSRNPFLNNTRPRLRFSPYQIPMSFSQSSGLLTTGIPSTMSAESESSKSGSRESSPMSEHHSHKTGNGQNTGSPKSSGKDSINELQNIQRLVSGLEKHRDASPRSVSPK
Protein: Dihydrosphingosine 1-phosphate phosphatase LCB3 (EC 3.1.3.-) (Long-chain base protein 3) (Sphingolipid resistance protein 2) (P47013)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Dihydrosphingosine 1-phosphate phosphatase required for efficient ceramide synthesis from exogenous sphingoid bases. Involved in endocytosis and calcium-mediated signaling.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:10477278, ECO:0000269|PubMed:10563329, ECO:0000269|PubMed:9353337}; Multi-pass membrane protein {ECO:0000269|PubMed:10477278, ECO:0000269|PubMed:10563329, ECO:0000269|PubMed:9353337}.
Interaction partners:
- Sphingosine-1-phosphate lyase
- Sphingolipid C4-hydroxylase SUR2
- Sphingoid long chain base kinase 4
- Sphingoid long chain base kinase 5
- Ceramide synthase LAG1
- Dihydrosphingosine 1-phosphate phosphatase YSR3
- Ceramide synthase LAC1
- Alkaline ceramidase YDC1
- 3-ketodihydrosphingosine reductase TSC10
- Serine palmitoyltransferase 2
Sequence:
MVDGLNTSNIRKRARTLSNPNDFQEPNYLLDPGNHPSDHFRTRMSKFRFNIREKLLVFTNNQSFTLSRWQKKYRSAFNDLYFTYTSLMGSHTFYVLCLPMPVWFGYFETTKDMVYILGYSIYLSGFFKDYWCLPRPRAPPLHRITLSEYTTKEYGAPSSHTANATGVSLLFLYNIWRMQESSVMVQLLLSCVVLFYYMTLVFGRIYCGMHGILDLVSGGLIGIVCFIVRMYFKYRFPGLRIEEHWWFPLFSVGWGLLLLFKHVKPVDECPCFQDSVAFMGVVSGIECCDWLGKVFGVTLVYNLEPNCGWRLTLARLLVGLPCVVIWKYVISKPMIYTLLIKVFHLKDDRNVAARKRLEATHKEGASKYECPLYIGEPKIDILGRFIIYAGVPFTVVMCSPVLFSLLNIA
Protein: WD repeat-containing protein 35 (B7ZD88)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|PIRNR:PIRNR037536}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|PIRNR:PIRNR037536}.
Interaction partners:
- Tetratricopeptide repeat domain 21B
- Intraflagellar transport 140 homolog
- WD repeat domain 19.
- Intraflagellar transport 80 homolog
- Intraflagellar transport protein 172 homolog
- Uncharacterized protein.
- Cytoplasmic dynein 2 light intermediate chain 1
- WD repeat domain 34
- Cytoplasmic dynein 2 intermediate chain 1 isoform X2
- Dynein cytoplasmic 2 heavy chain 1.
Sequence:
MFIYLSKKIAIPNNTVLKCVSWNKDQGFIACGGEDGLLKVLKLETYTDDAKLKGLAAPSNLSMNQTLEGHSGAVQVVTWNEQYQKLTTSDQNGLIIVWMLYKGSWYEEMINNRNKSVVRSMSWNADGLKICIVYEDGAVIVGSVDGNRIWGKELKGTQLAHVAWSPDSKILLFGMANGEIHIYDNQGNFIMKMSMSCLANVTGALSIAGIHWYPGTEGYLEPECPCLAVCFTNGHCQVMRHESDDSPVIIETGMWNVASIQWNHCGSVLAIAGSLRNSGAEKEMNVVHFYTPFGEHLRTLKVPGKQMTAVSWEGGGLRIGLAVDSYIYFANIRPDYKWGYCSNTVVYAYTRPDRLEYSVVFWDTKNNERFVKYVKSLMSITTCGDFCILATKADDTHPQEDTEAEAGSAMAFNELSNQNTSKDRSKRRKYVLVLCNSIGTPQDSKYIDIDPLFVTMTKTHVIAASREAFYIWQYRVAKKLTALEINQVTKTRKEGRERVYHIDDSPSGTSDGTLNFAKAFTATRDPICCITASDKMLLVGRESGILQRYSLPNISLLQKYSLTSRPYQLSLNCNSSRLAIIDITGVLTFLDVETRGSMGDAEGGSTAGDPSKFERKDVWDMKWANDNPDLFSMMEKTRMYVFRNLDPEEPIQTSGFICHFEDLEIKSVLLDEIMRDPDVPNKDYLMNFEIRSLRDSRALIEKVGIEDASQFIEDNPHPRLWRLLAEAALQKLDLKMAEQAFVRCRDYQGIEFVKRLSNLQSEAMKQAEVAAYFSRFEEAERMYLDMDRRDLAISLRIKLGDWFRVLQLLKTGSGDSDDALLEQAYNAIGDYFADRQKWLNAVQYYLQGRNQERLAECYYMLEDYDGLERLANSLPENHKLLPDIGQMFVTVGMCEQAVSAFLKCNQPKAAVDACVHLNQWNKAVELAKNHSMKEIGPLLSKYASHLLEKNKTLEAVELYRKAHHFLDAAKLMYKIAEEEAKKRTRPLRVKKLYVLAALLVEDFHTQIKSSQQSKTKGKKSEATSALAGLLEEDESSSDSRILDDAWRGAEAYHFFLLAQRQLYDGKVDAAMRTALHLRDYEDIIPAVEIYSLLAICSSANGAFGTCSRAFIKLESLETLTPDQRQLYEDLALEIFTKHSPRDTRQSQRDSLTEGPEGKLPTCIVTGRVISEYQFWMCSVCKHCALEQEITQQNFCPLCHSTVG
Protein: Small ribosomal subunit protein RACK1y (Guanine nucleotide-binding protein subunit beta-like protein B) (Receptor for activated C kinase 1B) (Q9C4Z6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Minor component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. Involved in multiple hormone responses and developmental processes. MAPK cascade scaffolding protein involved in the protease IV and ArgC signaling pathway but not the flg22 pathway.
Interaction partners:
- Large ribosomal subunit protein uL4y
- Small ribosomal subunit protein eS1z
- Large ribosomal subunit protein uL4z
- Small ribosomal subunit protein eS12y
- Small ribosomal subunit protein eS10x
- Small ribosomal subunit protein eS12z
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL24z
- Large ribosomal subunit protein eL8y
- Small ribosomal subunit protein uS2z
Sequence:
MAEGLVLKGTMCAHTDMVTAIATPVDNSDVIVTSSRDKSIILWKLTKEDKSYGVAQRRMTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLGECKYTISEADGHKEWVSCVRFSPNTLVPTIVSASWDKTVKVWNLQNCKLRNTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAGSIIHSLCFSPNRYWLCAATENSIRIWDLESKSVVEDLKVDLKAEAEKTDGSTGIGNKTKVIYCTSLNWSADGNTLFSGYTDGVIRVWGIGRY
Protein: Formate--tetrahydrofolate ligase (EC 6.3.4.3) (10-formyletrahydrofolate synthetase) (FHS) (FTHFS) (Formyltetrahydrofolate synthetase) (Q9SPK5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Bifunctional dihydrofolate reductase-thymidylate synthase
- Bifunctional dihydrofolate reductase-thymidylate synthase 2
- Bifunctional dihydrofolate reductase-thymidylate synthase 1
- Bifunctional protein FolD 1
- Bifunctional protein FolD 3, chloroplastic
- Bifunctional protein FolD 2
- Serine hydroxymethyltransferase 1, mitochondrial
- Bifunctional protein FolD 4, chloroplastic
- Serine hydroxymethyltransferase 7
- Serine hydroxymethyltransferase 6
Sequence:
MSSSTRKLEVVSPVPADIDIANSVEPLHISEIAKDLNINPLHYDLYGKYKAKVLLSAFDELQGQEDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAYLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNNLLAAAIDTRIFHETSQSDKALFNRLCPPNKEGKRSFSDIMFRRLTKLGISKTSPEELTPEEIKKFARLDIDPASITWRRVMDVNDRFLRKITIGQGPEEKGMTRETGFDISVASEIMAVLALTTSLGDMRERLGKMVIGNSKAGDPITADDLGVGGALTVLMKDAINPTLMQTLEGTPVLVHAGPFANIAHGNSSIVADKIALKLVGPGGFVVTEAGFGSDIGTEKFMNIKCRYSGLTPQCAIVVATVRALKMHGGGPDVVAGRPLDRAYVSENVSLVEAGCVNLAKHISNTKAYGVNVIVAVNMFATDTEAELNAVRKFSMDAGAFDAVVCSHHAHSGKGAVDLGIAVEKACQNITQPLRFLYPLDIGIKDKIEAIAKSYGASGVEYSDQAEKQIEMYTQQGFSNLPICMSKTQYSFSHDASKKGAPSGFVLPIRDVRGSIGAGFIYPLVGTMSTMPGLPTRPCFYEIDIDTETGKVRGLS
Protein: Mediator of RNA polymerase II transcription subunit 19 (Mediator complex subunit 19) (RNA polymerase II mediator complex protein rox3) (Q9Y7N2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 4
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 20
- Mediator of RNA polymerase II transcription subunit 8
Sequence:
MAQAPEYHYVGSVDYQPTRPSAHQNLIELYGLTELAKKVGRVDEFGNKRKMRRSYKAYIQDLPGYNEILRDNTIKQWLTNPIREEVPIDIEFLHHVFSVEPGIIPGFNPKVFGLEDDVVMGNVSRDSSQPRSPSRRKK
Protein: Tropomyosin 2 (beta) (Tropomyosin beta chain isoform X1) (A0A0R4IM99)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MEAIKKKMQMLKLDKENAIDRAEQAEIDKKGAEDKCKQLEEELLALQKKLKGVEDELDKYSESLKDAQEKLEQAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRATKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERSEERAEVAEAKSGDLEEELKNVTNNLKSLEAQAEKYSTKEDKYEEEIRVLTDKLKEAETRAEFAERSVAKLEKTIDDLEEKVAQAKEENLNMHQVLDQTLLELNNL
Protein: 26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (Q5VWC4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATTGTEGERDSDDALLKMTISQQEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKK
Protein: Protein kinase domain-containing protein (A0A384L3L6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MESMVKKLKQNLRTGSWKKKEKSMKKERWFLENGSIFLKELIVDCNGKSIPIRSFTSSQIRKATKNFDLSCFVAEEGFYIWYKGVIEDRSYMIKRFSEYKVTDYRVSEVYKDIVLSARMSNHNNFLKLLGCCLEFPFPVLVFEFAEHGVLNYRGGITVNGEESLLPLSLRLKIGKEIANALAYLHMAFPKIIIYRDVKPLHVFLDNNWTAKLSDLSFSISLEEGKSQIEAEDVLGTYGYLDPLYFATRIVTEYTDVYSFGVFLMVVITGISVYFTGSDGYPVGILGYMKGLAENGKLNEIVYPMIMKEMTSAQRLQVEACVLLALRCCEERVEDRPKMIQVAKELKRIEHHVLRS
Protein: Kiwellin-1 (ZmKWL1) (A0A1D6GNR3)
Organism: Zea mays (Maize)
Function: Specifically blocks the catalytic activity of the chorismate mutase Cmu1 from the fungal pathogen Ustilago maydis. Hinders substrate access to the active site of Cmu1 through intimate interactions. A structural feature specific to the fungal secreted Cmu1 called extensive loop region (ELR) is required for the intimate interaction. Does not interact with its own chorismate mutases. The secreted fungal Cmu1 presumably affects biosynthesis of the plant immune signal salicylic acid by channelling chorismate into the phenylpropanoid pathway.
Subcellular location: Secreted, extracellular space, apoplast {ECO:0000269|PubMed:30651637}.
Interaction partners:
- Chorismate mutase 1, chloroplastic
- chorismate mutase
- Chorismate mutase 2, cytosolic
- chorismate mutase
Sequence:
MATVGGNRALYAVVALPLLATLLHGPMRLSHAFPYRSLLQTCQPSGSIQGRSGNCNTENGSECCKNGRRYTTYGCSPPVTGSTRAVLTLNSFAEGGDGGGAAACTGKFYDDSKKVVALSTGWYNGGSRCRKHIMIHAGNGNSVSALVVDECDSTVGCDKDHNFEPPCRNNIVDGSPAVWDALGLNKDDGQAQITWSDE