wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized protein (Q381P9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGGSSSREMMNPYAVNTPLMGICLASIMFNSVQGRTLRSSNVFNNLILIYALGFSTGLSTVMQQPIWGAKVGIAAALGFTFGPNLRLIYLQRLFPDYVRYGIGSVYIAYHSLQWYSEVHAWEDAMEDEVAE
Protein: Neuron navigator 2 (E9PLU3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLWPRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKV
Protein: Uncharacterized protein (G8BHG5)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Interaction partners:
Sequence:
MGEIESYCNKELGPLPTKAPTLAKNVLDLFSLKGKVASVTGSSGGIGWAVAEAYAQAGADVAIWYNSHPADEKAEHLQKTYGVRSKAYKCNISDPKSVEETISQQEKDFGTIDVFVANAGIPWADGPVIDLENYDAWNKLINTDINGVFYCAHSIGKIFKKNGKGSLIITASLAGSVVTIPQQQTPYNTAKAACLHLAKSLAVEWAPFARVNTVSPGYFETEINGFADEDMREKWYQLTPLGRMGITEELVGGYLYFASNASTFTTGSDLIIDGGFTCP
Protein: RNA-binding protein BRN1 (Protein BRUNO-LIKE 1) (AtBRN1) (Protein RNA-BINDING PROTEIN-DEFENSE RELATED 1) (AtRBP-DR1) (Q8LFS6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: RNA-binding protein involved in the regulation of flowering time. Acts as repressor of the activity of SOC1, a transcriptional activator of flowering time. Binds to the 3'-UTR of SOC1 mRNA in the cytoplasm and participates in SOC1 mRNA decay, mediated by the distal region of the SOC1 3'-UTR. Acts as positive regulator of salicylic acid (SA)-mediated immunity. May act on SA signaling-related genes at a post-transcriptional level.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20636102, ECO:0000269|PubMed:23437850}.
Interaction partners:
- RNA-binding
- RNA-binding
- KH domain-containing protein
- TIP41-like protein
- Protein transport protein Sec61 subunit beta
- Protein transport protein Sec61 subunit gamma-2
- At1g10020
- Transducin/WD40 repeat-like superfamily protein
- RNA binding
- Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 1
Sequence:
MAEAKEENREKNEEEESVKLFVGQIPKHMSESQLLTLFQEFAVVDEVNIIKDKITRASRGCCFLLCPSREEADKLVNACHNKKTLPGANSLLQVKYADGELERLEHKLFVGMLPKNVSEAEVQSLFSKYGTIKDLQILRGAQQTSKGCAFLKYETKEQAVSAMESINGKHKMEGSTVPLVVKWADTERERHTRRLQKAQSHIARLGNGDPTNPSLFGALPMGYVPPYNGYGYHQPPGTYGYMLPPIQNQAAFSNMIAQPNQGNNNALQGTSPDSVPPRLARRNFPMPPGNYMGSGYPAMRGHPFPFAYPRGIVSPRPLSSSPGSISPGMSTPLGIGLSSVVQTEGPEGANLFIYNIPREFGDQELAAAFQSFGIVLSAKVFVDKATGVSKCFGFVSYDSQAAAQNAIDMMNGRHLGGKKLKVQLKRDSNNGQPSSNPSLIS
Protein: Transcription initiation factor IIF subunit alpha (M0R0R9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU366044}.
Interaction partners:
Sequence:
MSLNTSFEFLRNTPCLSSLLPKAEFTIISTSWVPPNLRPSICSSSAWGQERMGLASLADWESLESSVSSVARQNRLNEAGNTTKKYNIMAFNAADKVNFATWNQARLERDLSNKKIYQEEEMPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDK
Protein: Uncharacterized protein YfdS (P76515)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized protein YfdT
- Uncharacterized protein YfdR
- Uncharacterized protein YfdP
- Uncharacterized protein YfdQ
- Uncharacterized protein YfdK
- Uncharacterized protein YgeI
- Killing protein KilR
Sequence:
MRMNVFEMEGFLRGKCVPRDLKVNETNAEYLVRKFDALEAKCAALENKIIPVSAELPPANESVLLFDANGEGWLIGWRSLWYTWGQKETGEWQWTFQVGDLENVNITHWAVMPKAPEAGA
Protein: Wu:fc83e05 protein (A1L1W7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MFVCFLLCWTGVDAVFNLKYTVEEELRAGTKIANVTADAKVAGFALGNRQPYLRVISNSEPRWVNLSPAGLLITKQKIDRDAVCRQTPKCFISLEVMSNSMEICVIKIEIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSDNDSGANGKVQCRLQGNVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRGMSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYSISEGDMAYFEIDQINGEVRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLNAQEQIGPVNLSLIFIIALGSIAVILFVTMIFVAVKCKRDNKEIRTYNCRVAEYSYGNQKKSSKKKKLSKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNSRNAAPNHGYHHTFTGQGPQQPDLIINGMPLPETENYSIDSSYVNSRAHLIKSTSTFKDMEGNSLKDSGHEESDQTDSEHDVQRGHYADTAVNDVLNMTVPSNNSQIPDQDQSEGFHCQDECRILGHSDRCWMPRVPIPARAKSPEHGRNVIALSIEATTVDVPHYEDCGTTKRTFATFGKDGPDEDRAEQRGRRQTAEPAVCSPKTNGAVREAGNGREAVSPITSPVHLKSPQSKAPSTYNTLKCRDAERIANHSLLRQPEGKDSEPAMREINTLLQDGRDKESPGSKRLKDIVL
Protein: Ent-kaurenoic acid oxidase (OsKAO) (EC 1.14.14.107) (Cytochrome P450 88A5) (Protein REDUCED POLLEN ELONGATION 1) (Q5VRM7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in gibberellin (GA) biosynthesis. Catalyzes three successive oxidations of ent-kaurenoic acid giving gibberellin 12 (GA12), a key step in GAs biosynthesis. GAs, which are involved many processes, including stem elongation, play a central role in plant development (Probable). Required for pollen germination and elongation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O23051}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Gibberellin 20 oxidase 1
- Gibberellin 20 oxidase 3
- Os06g0570566 protein
- Ent-kaurene oxidase 2
- Ent-sandaracopimaradiene 3-hydroxylase
- Ent-kaurene oxidase-like protein 1
- Ent-kaurene oxidase-like 3
- Nitrate reductase
- Nitrate reductase 1
- Nitrate reductase
Sequence:
MVMEGMGMAAAWAAGDLWVLAAAVVAGVVLVDAVVRRAHDWVRVAALGAERRSRLPPGEMGWPMVGSMWAFLRAFKSGNPDAFIASFIRRFGRTGVYRTFMFSSPTILAVTPEACKQVLMDDEGFVTGWPKATVTLIGPKSFVNMSYDDHRRIRKLTAAPINGFDALTTYLSFIDQTVVASLRRWSSPESGQVEFLTELRRMTFKIIVQIFMSGADDATMEALERSYTDLNYGMRAMAINLPGFAYYRALRARRKLVSVLQGVLDGRRAAAAKGFKRSGAMDMMDRLIEAEDERGRRLADDEIVDVLIMYLNAGHESSGHITMWATVFLQENPDIFARAKAEQEEIMRSIPATQNGLTLRDFKKMHFLSQVVDETLRCVNISFVSFRQATRDIFVNGYLIPKGWKVQLWYRSVHMDDQVYPDPKMFNPSRWEGPPPKAGTFLPFGLGARLCPGNDLAKLEISVFLHHFLLGYKLKRANPKCRVRYLPHPRPVDNCLATITKVSDEH
Protein: Chorionic somatomammotropin hormone (Placental lactogen) (PL) (P16038)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted.
Interaction partners:
- Prolactin receptor
- Tyrosine-protein kinase
- Pro-opiomelanocortin
- Growth hormone receptor
- Uncharacterized protein
- Oxytocin-neurophysin 1
- Progonadoliberin-1
- Leptin receptor
- Insulin-like growth factor 1
- Signal transducer and activator of transcription 5A
Sequence:
MAPASSHREHQWTCNLVRGSRLLLLLVVSNLILCQGQAQHPPYCRNQPGKCQIPLQSLFDRATTVANYNSKLAGEMVNRFDEQYGQGINSESKVINCHTSSITTPNSKAEAINTEDKILFKLVISLLHSWDEPLHHAVTELANSKGTSPALLTKAQEIKEKAKVLVDGVEVIQKRIHPGEKNEPYPVWSEQSSLTSQDENVRRVAFYRLFHCLHRDSSKIYTYLRILKCRLTSCET
Protein: CCHC-type zinc finger, nucleic acid binding protein a isoform X1 (CCHC-type zinc finger, nucleic acid-binding protein a) (F1Q6Z5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Muscleblind-like protein 3 isoform X2
- Uncharacterized protein
- Muscleblind-like-splicing regulator 1.
- Nucleolar and coiled-body phosphoprotein 1
- Heterogeneous nuclear ribonucleoprotein K
- SERPINE1 mRNA-binding protein 1 isoform X1
Sequence:
MDMSTSECFGCGRSGHWIKNCPNAGRGRGRGRGRGKDLFCYRCGEQGHIARDCEQTEDACYNCHRSGHISRDCKEPKKEREQCCYNCGKAGHVARDCDHANEQKCYSCGGFGHIQKLCDKVKCYRCGEIGHVAVQCSKATEVNCYNCGKTGHLARDCSIEASA
Protein: Probable cysteine protease RD21C (EC 3.4.22.-) (Q9LT78)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable thiol protease.
Interaction partners:
- UPF0235 protein At5g63440
- Developmentally-regulated G-protein 3
- DNA polymerase epsilon subunit B
- Mitochondrial succinate-fumarate transporter 1
- At1g49170
- Developmentally-regulated G-protein 2
- Developmentally-regulated G-protein 1
- Casein kinase II subunit alpha-4, chloroplastic
- Casein kinase II subunit alpha-3
- Casein kinase II subunit alpha-1
Sequence:
MATSIKSITLALLIFSVLLISLSLGSVTATETTRNEAEARRMYERWLVENRKNYNGLGEKERRFEIFKDNLKFVEEHSSIPNRTYEVGLTRFADLTNDEFRAIYLRSKMERTRVPVKGEKYLYKVGDSLPDAIDWRAKGAVNPVKDQGSCGSCWAFSAIGAVEGINQIKTGELISLSEQELVDCDTSYNDGCGGGLMDYAFKFIIENGGIDTEEDYPYIATDVNVCNSDKKNTRVVTIDGYEDVPQNDEKSLKKALANQPISVAIEAGGRAFQLYTSGVFTGTCGTSLDHGVVAVGYGSEGGQDYWIVRNSWGSNWGESGYFKLERNIKESSGKCGVAMMASYPTKSSGSNPPKPPAPSPVVCDKSNTCPAKSTCCCLYEYNGKCYSWGCCPYESATCCDDGSSCCPQSYPVCDLKANTCRMKGNSPLSIKALTRGPAIATTKSTNMLVGSA
Protein: Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) (Q5XI55)
Organism: Rattus norvegicus (Rat)
Function: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- UV excision repair protein RAD23 homolog B
- E3 ubiquitin-protein ligase AMFR
- Transitional endoplasmic reticulum ATPase
- UBX domain-containing protein 1
- 26S proteasome regulatory subunit 4
- RAD23 homolog A, nucleotide excision repair protein.
- Derlin
- Coiled-coil domain containing 12
- Transmembrane protein 259
Sequence:
MASATLGSSSSSASPAVAELCQNTPETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAVERRSRLDGSSQKVEFSQHPAAVRLPAEQPEDPTGLMQHSGNQPGQPLSLPSAPLVVGDSTIFKVLQSNIQHVQLYENPVLQEKALACIPVNELKRKSQEKLFRARKLDKGTKVSDEDFLLLELLHWFKEEFFHWVNNVVCSRCGRETRSRDEALPPNDDELKWGAKNVEDHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCKHEEVMSRRTKVKEELLRETINGLNKQRQLLLSESRRKELLQRIIVELVEFISPKTPRPGELGGRVSGSLAWRVARGETCLERKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNNANISGWENGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDNVSIRTSSQSFETGSVRWKLRSEMAQVNLLGDRNLRSYDDFCGATEVTLEAELSRGDGDVAWQHTQLFRQSLNDHAENGLEIIITFSDL
Protein: GTPase-activating protein (Ras GTPase-activating protein 1) (P48423)
Organism: Drosophila melanogaster (Fruit fly)
Function: Inhibitory regulator of the Ras-cyclic AMP pathway. May function as a negative regulator of Ras85D/Ras1 in the sev signaling pathway. Acts cell autonomously in cone cell precursors as a negative regulator of R7 photoreceptor cell determination.
Interaction partners:
- Ras-like protein 1
- Protein sprouty
- GH13542p
- Tyrosine-protein phosphatase corkscrew
- Inosine-5'-monophosphate dehydrogenase
- GH16429p
- Epidermal growth factor receptor
- LD23779p
- GTP-binding protein Rheb homolog
Sequence:
MLLKKKRYMFDERDDNNINSPVAVEPSSNNNKMADTREVRIEEQLKVKIGEAKNLSSRNAANTSCSTQGTRDVYCTIALDQEEICRTPTIERTLTPFFGEEHQFKIPRRFRYLTIYLWDRDMKQDKPIGKIAIKREELHMYNHKDHWFSLRPVDQDSEVQGMVNVEVAFTEAQQTQSLSEGIDLGQHTLRHHQNLPHHSHQQRAHLNDYKENSELSNIQRASAAAASSSSAAMTLKTRAAGLFGHVHHPPSQTQHFPIINTTSTSSDQLSNWKSHGRFVGVTIKVPACVDLAKKQGTCDPFVVCTAHYSNKHQVTRRTKQRKKTVDPEFDEAMYFDLHIDADAGSTNTTGSNKSAGSLESSANKGYSIYPVGGADLVEIVVSVWHDAHGAMSDKVFLGEVRLPMLNKQEQQAVNPSAWYYLQPRSMTHSSRSLNATPRSCATPPGTRLSVDSTIGSLRLNLNYTADHVFPLATYDDLMNLLLESVDQRPITVSAVSILGELVSGKTEVAQPLVRLFTHTERIAPIIKALADHEISHLTDPTTIFRGNTLVSKMMDEAMRLSGLHYLHQTLRPVLSQIVAEKKPCEIDPSKIKDRSAVDTNLHNLQDYVERVFEAITKSADRCPKVLCQIFHDLRECAGEHFPSNREVRYSVVSGFIFLRFFAPAILGPKLFDLTTERLDAQTSRTLTLISKTIQSLGNLVSSRSSQQTCKEEFTVELYKKFCTEQHVDAVKHFLEVISTPSHASSSVHPAAAAATPLEPVLLKEGLMTKYPTSRKRFGRQFKQRHFRLTTHSLSYAKSKGKQPICDIPLQEIASVEQLKDKSFKMQNCFKIVHNDRSLIVQTTNCVEEREWFDLLHKICLMNSIRMQYFHPSAFVSGFYSCCGRSDENSPGCKKVLDKTMDYFQMDLVTALDPALDLQRIHTLIMSNMSVLESLLDPLTYHQSLSQTQHQQHNPLVPLATDLQKHSPQAFAEFKRTIEKLREKAYAIDRDHRDYKQGITRQLKYGSRQAPIGDDNYWHMMRAAGQLNQQHHQQQQHQQQQQQQQQQQLQQFQPQPVLPQMQNVRAYPYQPATSNMNAYCLHNMQYQQQRLPFHQQQQQHHQQLQQQQSQFQPLRSHQLQRHNNNLNNNNCGNGSSSSPSSTTSSVVAAPPSTTSSSQPAPPIY
Protein: Putative nuclear RNA export factor SDE5 (Protein SILENCING DEFECTIVE 5) (Q9LUQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in sense transgene post-transcriptional gene silencing (S-PTGS). Not involved in repeat-induced transgene silencing (IR-PTGS). Essential component of the trans-acting short interfering RNA (tasiRNA) pathway. Required for the production of tasiRNAs. Acts together with RDR6 in generating double-stranded RNA from specific single-stranded RNAs. May be involved in the transport of RNA molecules that are converted into a double-stranded form by RDR6. Involved in virus-induced silencing. Not involved in the biogenesis of microRNAs and 24 nt siRNAs produced by DCL3.
Interaction partners:
- Protein SUPPRESSOR OF GENE SILENCING 3
- F7H2.18 protein
- RNA-dependent RNA polymerase 6
- Probable RNA helicase SDE3
- Protein argonaute 1
- Protein RAE1
- Dicer-like protein 4
- Double-stranded RNA-binding protein 4
- Protein argonaute 7
- Endoribonuclease Dicer homolog 2
Sequence:
MSKIASSSNSDPDSRSLQVLLDTFGSRFSLDDIAAAYCQASQNVDVAGEILSAMAEKTPQCDQVEMKTATSKPTQVYVPKEVPRQEDSKAKVWRPKRNSISNGTVSSVIGKEYARTRPISNAPKEATKPLKINSRDIPETEIWSEEMRKSNEGKISRAPTDVEEFIVKMLGEGFQASQEVIHQVLGVCGYDVKKSTEKLLDFSDTKKYADVGISNEVMSKVDPQRQSTSCNQMELQKISQSVGARTFTGSQEGRNAKNGLEKEVLEALFSGAERYVDKPKVTRHFGERRPGVAGRPVFKPLEDPFQERVVAVKQSSNTSKEDDDENEFKAHRKAVREHLNQMKEYYGAAAEAFSKGETERAHRLVEKGHFFGQKAREADDKSVAKMIDVNQEDDSTYEEDEVVTVNMNEHEAKEALRLLKRQLIYFSGISSFKYLRVQLGEKKEDFKSKRKHIVKLLEGESIPWTEEDGGLVIMIRVDEIDPKKLSFAKK
Protein: Hemoglobin beta 2 (Hemoglobin beta 3) (Hemoglobin subunit beta) (V5N6P9)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Interaction partners:
- Hemoglobin alpha 2
- Hemoglobin subunit alpha-2
- Hemoglobin subunit alpha
- Hemoglobin alpha 4
- Hemoglobin subunit alpha
- Hemoglobin subunit alpha
- Hemoglobin alpha 2
- Hemoglobin alpha 1
Sequence:
MVHWTDAERHIIADLWGKINHDEIGGQALARLLIVYPWTQRYFSSFGNLSNAAAIIGNPKVAAHGKVVLGGLTKAVQNLDNVKGIYTQLSTLHSEKLHVDPSNFTLLGDTFTVTLAANFGPSVFTPEVHETWQKFLNVVVAALGKQYH
Protein: Killer cell lectin-like receptor subfamily B member 1B allele A (CD161 antigen-like family member B) (Lymphocyte antigen 55b) (Ly-55b) (NKR-P1 34) (Natural killer cell surface protein NKR-P1B allele SJL/BALB) (NKR-P1B) (CD antigen CD161b) (P27812)
Organism: Mus musculus (Mouse)
Function: Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- C-type lectin domain family 2 member D
Sequence:
MDSTTLVYADLNLARIQEPKHDSPPSLSPDTCRCPRWHRLALKFGCAGLILLVLVVIGLCVLVLSVQKSSVQKICADVQENRTHTTDCSVNLECPQDWLSHRDKCFRVFQVSNTWEEGQADCGRKGATLLLIQDQEELRFLLDSIKEKYNSFWIGLRFTLPDMNWKWINGTTFNSDVLKITGDTENGSCASISGDKVTSESCSTDNRWICQKELNHETPSNDS
Protein: Deoxynucleoside kinase (F5CTF3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL
Protein: Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1) (Q14722)
Organism: Homo sapiens (Human)
Function: Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the closure of KCNA1, KCNA2 and KCNA5 channels. Accelerates KCNA4 channel closure. Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4. Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6 (By similarity). Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1. Enhances KCNB1 and KCNB2 channel activity (By similarity). Binds NADPH; this is required for efficient down-regulation of potassium channel activity. Has NADPH-dependent aldoketoreductase activity (By similarity). Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17540341}. Membrane {ECO:0000250|UniProtKB:P63144}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:17540341}; Peripheral membrane protein {ECO:0000269|PubMed:17540341}; Cytoplasmic side {ECO:0000269|PubMed:17540341}. Note=Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits. {ECO:0000269|PubMed:17540341}.
Interaction partners:
- Potassium voltage-gated channel subfamily A member 1
- Potassium voltage-gated channel subfamily A member 5
- Potassium voltage-gated channel subfamily A member 4
- Potassium voltage-gated channel subfamily A member 2
- Potassium voltage-gated channel subfamily A member 3
- Voltage-gated potassium channel KCNC1
- Potassium voltage-gated channel subfamily A member 6
- Potassium voltage-gated channel subfamily V member 1
- Leucine-rich glioma-inactivated protein 1
- Potassium voltage-gated channel subfamily B member 1
Sequence:
MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
Protein: Heterogeneous nuclear ribonucleoprotein R (A0A8I6GJB1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLVEAGLPQKVAERLDEIFQTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRNYYYHPPPRMPPPMRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK
Protein: 14-3-3-like protein B (14-3-3f protein) (D9Z6D3)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
- Protein TIME FOR COFFEE-like
- Protein PXR1-like
- arsenate reductase
- arsenate reductase
Sequence:
MATMVPDNLSRDQYVYLAKLAEQAERYEEMVQFMQKLVLGSTPASELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRKNEEHVVLVKEYRSKVESELSDVCASILTLLDSNLIPSAAASESKVFYLKMKGDYHRYLAEFKVGDERKAAAEDTMLSYKAAQDIALTDLAPTHPIRLGLALNYSVFYYEILNQSDKACSMAKQAFEEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDVQDQLDEP
Protein: Pectinesterase 2 (PE 2) (EC 3.1.1.11) (Pectin methylesterase 2) (AtPME2) (Q42534)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular location: Secreted, cell wall {ECO:0000305}.
Interaction partners:
- Pectate lyase
- Pectin lyase-like superfamily protein
- Pectate lyase
- Probable polygalacturonase At2g43860
- Pectin lyase-like superfamily protein
- Pectin lyase-like superfamily protein
Sequence:
MAPIKEFISKFSDFKNNKKLILSSAAIALLLLASIVGIAATTTNQNKNQKITTLSSTSHAILKSVCSSTLYPELCFSAVAATGGKELTSQKEVIEASLNLTTKAVKHNYFAVKKLIAKRKGLTPREVTALHDCLETIDETLDELHVAVEDLHQYPKQKSLRKHADDLKTLISSAITNQGTCLDGFSYDDADRKVRKALLKGQVHVEHMCSNALAMIKNMTETDIANFELRDKSSTFTNNNNRKLKEVTGDLDSDGWPKWLSVGDRRLLQGSTIKADATVADDGSGDFTTVAAAVAAAPEKSNKRFVIHIKAGVYRENVEVTKKKTNIMFLGDGRGKTIITGSRNVVDGSTTFHSATVAAVGERFLARDITFQNTAGPSKHQAVALRVGSDFSAFYQCDMFAYQDTLYVHSNRQFFVKCHITGTVDFIFGNAAAVLQDCDINARRPNSGQKNMVTAQGRSDPNQNTGIVIQNCRIGGTSDLLAVKGTFPTYLGRPWKEYSRTVIMQSDISDVIRPEGWHEWSGSFALDTLTYREYLNRGGGAGTANRVKWKGYKVITSDTEAQPFTAGQFIGGGGWLASTGFPFSLSL
Protein: pEARLI1-like lipid transfer protein 2 (Q9SU34)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable lipid transfer protein (LTP). May improve freezing survival. Seems to control the flowering process and lignin synthesis. Confers resistance to Botrytis cinerea.
Subcellular location: Secreted, cell wall {ECO:0000250}.
Interaction partners:
- AT5g13210/T31B5_30
- Phosphoglycolate phosphatase 1B, chloroplastic
- Protein LURP-one-related 2
- Transmembrane protein
- Thioredoxin H8
Sequence:
MASKNSASLALFFALNILFFTLTAGTNCRCNPSPKPRPLPNPKVPSPKVPTPSVPSPYVPTPSVPSPSVPTPSVPSPSVPSPNPTPVIPPRTPGSSGNCPIDALRLGVCANVLSGLLNVQLGQPSPQPCCSLIQGLVDLDAAVCLCTALRANVLGINLNVPISLSVLLNVCNRRLPSNFQCA
Protein: Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Polyadenylate-specific ribonuclease) (A0A494C0Q6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEIIRSNFKSNLHKVYQAIEEADFFAIDGEFSGISDGPSVSALTNGFDTPEERYQKLKKHSMDFLLFQFGLCTFKYDYTDSKYITKSFNFYVFPKPFNRSSPDVKFVCQSSSIDFLASQGFDFNKVFRNGIPYLNQEEERQLREQYDEKRSQANGAGALSYVSPNTSKCPVTIPEDQKKFIDQVVEKIEDLLQSEENKNLDLEPCTGFQRKLIYQTLSWKYPKGIHVETLETEKKERYIVISKVDEEERKRREQQKHAKEQEELNDAVGFSRVIHAIANSGKLVIGHNMLLDVMHTVHQFYCPLPADIINNTSLAELEKRLKETPFNPPKVESAEGFPSYDTASEQLHEAGYDAYITGLCFISMANYLGSFLSPPKIHVSARSKLIEPFFNKLFLMRVMDIPYLNLEGPDCNIQISWIDDTSAFVSLSQPEQVKIAVNTSKYAESYRIQTYAEYMGRKQEEKQIKRKWTEDSWKEADSKRLNPQCIPYTLQNHYYRNNSFTAPSTVGKRNLSPSQEEAGLEDGVSGEISDTELEQTDSCAEPLSEGRKKAKKLKRMKKELSPAGSISKNSPATLFEVPDTW
Protein: Chemosensory protein B 42c (A1Z6S2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRTLMLFVFGFASSWAADYELLLEDPDIFSPCTEPPPGSIGFHDAFDIGDLVVDQDMDIIHLSESVTSIWDVEPTDRISARFAIMHYNRGSWEPTVFSMATPDFCASMFDENQSWFKYWTKHISNRDEVMEKCFKTRGTVIMHNPFDLQLRLTDIRGATLRGRYKAVVTFEAVDEKDVPRRNSICFEIRGEAEKIN
Protein: Tachykinin-4 (Preprotachykinin-C) (PPT-C) [Cleaved into: Hemokinin (HK1) (Hemokinin-1) (Hemokinin-I) (HK-I)] (Q8CH01)
Organism: Rattus norvegicus (Rat)
Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Hemokinin induces plasma extravasation, mast cell degranulation, muscle contraction, salivary secretion and scratching behavior. Increases sperm motility. Induces potent analgesic effects and may play a role in pain modulation. Promotes survival of bone marrow B lineage cells and of cultured LPS-stimulated pre-B cells and may act as an autocrine factor required for B-cell survival and proliferation. Lowers systemic arterial pressure following intravenous injection. Induces interferon-gamma production and may play a role in the inflammatory response. Shows potent affinity and specificity for the NK-1 receptor.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Substance-P receptor
- Protachykinin-1
- Substance-K receptor
- Tachykinin-3
- Neuromedin-K receptor
Sequence:
MLPLLALFLLIGPAVSTTTRDREDLTFGAEAESWVTVNLKGIPVPSIELKLQELKRSRTRQFYGLMGKRVEGVHPIQSAERTGYQLGRIVQDLLGTRGLSIEGSCRQETNHQSAGPGAVARESLQSQRGRSEPPNHQQHVALSLGTEEDDQSSERAPRDASQMMPRPSRP