wanglab/gogpt-training-data huggingface dataset:
Protein: Cyclin B2 (G2/mitotic-specific cyclin-B2) (A9ZPH4)
Organism: Sus scrofa (Pig)
Interaction partners:
- Cell division cycle 2
- Cell division cycle protein 20 homolog
- G2/mitotic-specific cyclin-B1
- Aurora kinase B
- Serine/threonine-protein kinase PLK
- Histone H3-like centromeric protein A
- M-phase inducer phosphatase 3
- Kinesin-like protein
- Anaphase-promoting complex subunit 4
- Cell division cycle associated 8.
Sequence:
MALPRRPTVSTDLENIDIGLNSKPKSHVTIRRAVLEEIGNRVTTRATQVAKKAQNIKVLVPPSKTTNANKPLKPTASVKPVQMEMLAPKGPSPTPEDMKEESLCQAFSDALLCKIEDIDNEDGENPQLCSDYVKDIYQYLKQLEVLHPINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVAIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIKDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVMKVNENLTKFIAIKNKYASSKLLKISTIPQLNSKAIQELASPLMGRS
Protein: MutL homolog 1 (A0A669KBK2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEV
Protein: Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein (Putative NTF2-containing RNA-binding protein) (Q84JH2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 24
- Calcium-dependent mitochondrial ATP-magnesium/phosphate carrier protein 3
- Nuclear transport factor 2 family protein
- At5g46870 family protein)
- At1g13730
- Ubiquitin carboxyl-terminal hydrolase 3
- ATP synthase subunit beta-1, mitochondrial
Sequence:
MDSTAATKRVVDPLTVGSAFVNQYYYIFCNMPEHLPRFYQEISRVGRVGQDGVMRDFSTFQGISEELKRLTYGDCNSAEITSYDTQESHNGGFLLFVTGYFTLNERSRRKFTQTFFLAPQEKGFFVLNDILRFVNDDAKDNVPETIDGEVVSGINSTTPTIINGMKGSEQAACVSVNPVCKEVSKPLDNENAKDNVLVPEIANEVARTEITCKEVADDSQKNYDPDDGLADAPKKSYASVLKVTKDKFGVPAVSLPSPKKIPKDQEHQAPSDPSTGQILKDQGQQASSDPSQVIESDTVSESVDASENGHNQEAVAEGTSIYVRHLPFNANIDMLEAEFKQFGAITNGGIQVINQRGLGYPYGFVEFEEADAAHRAIEASPVKIGGLRAFVEEKLSTSRGKRGNGNVGYGNRNVGVGMRGRGSYGYGYDYRRGGRGPGGGGRSFNRRGNEYVASINSY
Protein: Nostrin (Disabled homolog 2-interacting protein 2) (Dab2-interacting protein 2) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer) (Q6WKZ7)
Organism: Mus musculus (Mouse)
Function: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8IVI9}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8IVI9}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8IVI9}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q8IVI9}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8IVI9}. Cytoplasm {ECO:0000269|PubMed:15596140}. Nucleus {ECO:0000269|PubMed:15596140}. Note=Enriched in selected actin structures. {ECO:0000250|UniProtKB:Q8IVI9}.
Interaction partners:
- Caveolin-1
Sequence:
MRDPLTDCSYNKVYKSLKEFAQHGDNFCKQITSVLQQRANLEISYAKGLQKLAVRLSKALQSTKKNCLSTAWAWASESMKSAADLHQKLGKAIELEAIKPTHQVLSMQEKKRKSLDNEVEKTANLVINNWNQQIKAKKKLMMSTKKHEALFHLVESSKQSLTQKEKQKLLNKLKKSTEKLEKEDESYYQKNMAGYSTRLKWESTLENCYKSMLELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKVDVEKDIQALMEETAILSIENKSELLLADYFEEDPKNPMDKERRKSLLKPKLGRLQRDIEKASRDKEGLERKLKALASSSSFSDAKSQKDMETLMDENSLKLDLLQANSYKLSSVLADLEQRPKPCHPCSTCIFKWKEKEHSHTYVKISRPLLTKRLEKAESKAPAGGQNNPSSSPSGSTVSQASKHLCKALYTFQARQDDELNLEKGDIVTVHEKKEEGWWFGSLKGKRGHFPAAYVEELPPKAGNTATQA
Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2) (P24135)
Organism: Rattus norvegicus (Rat)
Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Subcellular location: Membrane raft {ECO:0000250|UniProtKB:Q8CIH5}.
Interaction partners:
- Tyrosine-protein kinase
- B-cell linker protein
- Proto-oncogene vav
- Lymphocyte cytosolic protein 2
- Linker for activation of T-cells family member 1
- Platelet-derived growth factor receptor beta
- Receptor protein-tyrosine kinase
- Protein kinase C beta type
- phosphatidylinositol-4,5-bisphosphate 3-kinase
- SH3 domain-binding protein 2
Sequence:
MTTMVNVDTLPEYEKSQIKRALELGTVMTVFSARKSTPERRTVQMIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRHKADCCFTIFYGTQFVLSTLSLATDSKEDAVKWLSGLKILHQEAMNASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKTQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEDPVQDTPPTELHFGEKWFHKKVESRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFLVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLRLYQEKCNRRLREKRVSNSRFYS
Protein: Killer cell lectin-like receptor subfamily B member 1A (NKR-P1A) (CD161 antigen-like family member A) (Lymphocyte antigen 55A) (Ly-55A) (NKR-P1.7) (Natural killer cell surface protein P1-2) (NKR-P1 2) (CD antigen CD161a) (P27811)
Organism: Mus musculus (Mouse)
Function: Plays a stimulatory role on natural killer (NK) cell cytotoxicity.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- C-type lectin domain family 2 member D
- CD48 antigen
Sequence:
MDTARVYFGLKPPRTPGAWHESPPSLPPDACRCPRSHRLALKLSCAGLILLVVTLIGMSVLVRVLIQKPSIEKCYVLIQENLNKTTDCSAKLECPQDWLSHRDKCFHVSHVSNTWEEGLVDCDGKGATLMLIQDQEELRFLLDSIKEKYNSFWIGLRYTLPDMNWKWINGSTLNSDVLKITDDTENDSCAAISGDKVTFESCNSDNRWICQKELYHETLSNYVGYGH
Protein: Collagen alpha 1 type X (Q9Z1K4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
GYPGDPGLNGPKGNPGLPGPKGDPGVGGAPGLRGLVGPTGPKGVPGHNGEAGPRGEPGIPGTRGPIGPPGIPGFPGSKGDPGKPGAPGPAGIVTKGLNGPAGPPGRPGPRGHTGEPGLPGPPGPPGPPGPPSQAVIPDGFTKSGQRPRLSGMPLVSANQGVTGMPVSAFTVILSKAYPAVGAPIPFDEILYNRQQHYDPRSGIFTCKIPGIYYFSYHIHVKGTHVWVGLYKNGTPTMYTYDEYSKGYLDQASGSAIMELTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPI
Protein: Uncharacterized protein, isoform A (Uncharacterized protein, isoform C) (Q9VGH2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MILVVAIAAIILAIGAGGVLGENSSSCGPNFPAACSCGQEMYESEMQYVVNCTNAGLVNTSVLEFMPEQVEVLIFTGNRITELPWNVFGSINNYKQLRIVDMSSNHIREIRGKSYHHVPRVERLILNHNNLSISRYEDEVNHHHPRVFSNFINLQSLHLTDAFEDNSSPQLSEDLHDIFVNSQLVKLQKLHLEQNEITHFKDRNVFCDLPSLRDLHLGDNDLRDLNFEVRCLNNLRFLDLERNKFSFVKPTDLRVLNELEERPNRTANLIVDFNLNPFGCDCRTAPFRAWITTTRVTVRNKDSLMCFHSTGHVDAEPAHLLQMDMGQCADAIAAAATILNTAEDEPHYGDPEASHLQPQAHISGHTATLIFLLIVLTMILLGLLVALVYVSRDKLKYMITPVFDNVAKKVQYTSIKDEDCPEVHV
Protein: V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 57 kDa subunit) (Vacuolar proton pump subunit B) (P16140)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:2141385}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- V-type proton ATPase subunit D
- V-type proton ATPase subunit c'
- V-type proton ATPase subunit G
- V-type proton ATPase subunit E
- V-type proton ATPase subunit C
- V-type proton ATPase subunit F
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase subunit d
- V-type proton ATPase subunit a, vacuolar isoform
- V-type proton ATPase subunit c
Sequence:
MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI
Protein: Short transient receptor potential channel 4 (TrpC4) (Capacitative calcium entry channel Trp4) (Receptor-activated cation channel TRP4) (Q9QUQ5)
Organism: Mus musculus (Mouse)
Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Trpc4 deficient mice lack a store-operated calcium entry in endothelial cells.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9UBN4}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Short transient receptor potential channel 1
- Short transient receptor potential channel 5
- Short transient receptor potential channel 3
- Na
- Stromal interaction molecule 1
- Voltage-dependent T-type calcium channel subunit alpha-1H
- Voltage-dependent T-type calcium channel subunit alpha
- Bone morphogenetic protein receptor type-2
- Voltage-dependent T-type calcium channel subunit alpha
- Transient receptor potential cation channel subfamily V member 4
Sequence:
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQSANAASSADSDEKSQSEGNGKDKRKNLSLFDLTTLIHPRSAAIASERHNLSNGSALVVQEPPREKQRKVNFVADIKNFGLFHRRSKQNAAEQNANQIFSVSEEITRQQAAGALERNIELESKGLASRGDRSIPGLNEQCVLVDHRERNTDTLGLQVGKRVCSTFKSEKVVVEDTVPIIPKEKHAHEEDSSIDYDLSPTDTAAHEDYVTTRL
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q8SWX7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAGLIGAANGKHHHPHLISPTHTSLPAGICSSDSGISTLSAISPPLSTSTTTASGADGGVGGSPQLRTSPALSMLGSATATASGVTASSGCGLTAGILGPAASIDLGSSPLSHRNYSNSLKGFSFRRSFDDKIINTPYLSRAPAYTHGIPYPHFHGTQPAATTPHHLHLHHHGNGTAAGSGSGVGSGPGSGSGAGGLYQQPLSLASMTAALPLAPLYGSPLSLPLTSSQSTTKLSYRDDFLQQIGYLPTTRIYSTPTSIVDEDKAQQDFLSLSLSPPLNRRRDMPALRGPFVSLSEPRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQYCRGGYHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAIRDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSYISSIEKQTKSRAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLDKEDTTTTTSSTLNSNTTSSLASKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKVRLLSNRSPLPHTRKHWPGLHIRCGVHGKHLHSPHCEPTCKHTLHTKGTRNSYVLLLFHFIFALSLPLV
Protein: Guanidine nucleotide exchange factor (Q8I418)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Ran-specific GTPase-activating protein 1, putative
- Rab GDP dissociation inhibitor
Sequence:
MYEQDDEDKDIHKYIFPFFPKISTGLDHYACVAYYKNKPSIFTWGGNSCNQLGLGINNRFVNNPTVVCFFDSFIVASICCTNYATFVLVKKNVNDIGCSVYSFGKGNNGLLGYKKKRELPNFLEHEEKKNIQKVKEQMLQKVNDPLNQMVLDAFGIKKKEKEKEKKKKKKKNDIKKEEKEENNINNEKKNNNNNNNINSEKKKKNDINGHEAKYVQNKKFFYNEHNFKNDIGLPSDDDIYDDYNISGDESLLNFEADNISSIQNEDTNMDEDVYNNIVNDHTNEDRQSDINETIDKHSNDNDYDDEKKKEKMNIYKNKEKLYSNIKENDNKHDWFTPFPMKIVFPKKNTKIKFISCGDMHTLAICTGGVLYSWGYNNFGCIGNGTNQNVYEPTPIFLEPHSVDNNGDNNDDDYDDDNNNNSTYKFHKKEDSIKWDKKKNVVIHCSAGSKHSLACNLHGDIYSWGYGGNGRLGLGNIKSYNKPQLIKGLRNKRILYVCAGTSHSGCIDSNYNVYTWGNGKFYKLGHGNDDIDIYYPKLVECLNHNKKVCMLSFGCFNSLALNVKGDVYVWGTFNITNNYVNYYISKLPKQINTNYKCISIHASTYVCFGITLVGDLISFGNYKNYSYEKEINDNDSDDDLIKYLINKEVEEQHYNGDNKSVHTNKNNIISSYIVKKKDEHFDIHYIKEMRGKMYIKDIVTHFYNLDTMTYYMNKINKHIDNVTLNNNDNYYTYDNINGSHGNIFEKNKLVLKSKVKIIDGSDHFSVFLLESGKVYTAGYNKNGELGNGEFNLKKKFGVPILLNICVNKIIKIACGYNYVLCVSDVGLVYGWGKNDKSQLGIGVIKDFYEPVHVKNLTNVINIFAGYDHSACIINKLLDKGNTNGVNNVNNVNGVNGVNNYSSDECGDLYIWGNAESGKVGLGVDYTQGCILLPRKINIINKIYKCSLGNSHSLFLTNTNELYVCGSNNNGRLGLFEKSKMVCNIVSVPTKVILHNNIYIKDILAGNTYSIILSVDGFIYIFGEFIKGSNGNSNNMSCEVISLYNEITNVKYMNGKYEHVFFLTYDNKLFGIGNNKNCQILCDNEKENNYIKKPKLITYFLKENNKIIESIFSFHNVTFIQFNNSEIFAWGYTNNYHLCIGIPNNIKYLKHPTKIIKTWLTYDQKDLDYNGSCSDMELNEYNTTNNMSYNNYIKYINEITLVKKNINTTELFQNEYTYFGYYEEEIENFIYNIVIMNNIINWCHLQNLLKKEEYNNNMEYIKSFEKDIIDLYSKHIEVLLNLNIYEKQFNYLYLNYQNFILSNIANMKEQHLPNILYPFSTYIFDQNRIKLEQFIYIIQQQPVYLIILCLIHNYKNVKNVKQLMYGKMSYNSNKNTTHIYHNNINEQHIKNNYNIINSNYINHTYNYEQNDALKKYNSKDIQNKKYSFYKNSSNVLCSFIFDLYADFRNERVRTIFTIFLIKLGIEEIKNSLNVHSIFNIDTSIFFTLIQMLFFKKEILINFAQCLIDLDNPNSFVTLLDQLSRKVPKKNIPLNQQGVSNAKNMQHTKHLQTNTPMYGSAHHRENLLINDMYNDRMVVDKNIHVKNSTHMDLKNDGANKKKKIKKKKNNKKKNNKKKNNKKKNNKKKNNNNNNGGGDGDYSGDDIYSGDDIYSGDDDYSGDDDYSGDDIYSGDDIYSGDDIYSGDDIYSGDDIYSGDGINHSVNKLNKKKNVKREPNISSFIDNLNDDEKDKEFLNFIKGKTQNESDKKRLFVNDISCYKSGVPYNIPNINMEDENMYRNNISQEIQNENLDNNDNYVEINFVCIFEELCKIFLNIKFPDMFKIIIKELFKYFIIYEKNLNDEINQTNKIYFYQNHHTIYIPFFKLILMAIINPILKNMENIAHKFSYPNIFPHILNIRNKICDFLEILYLNKYESLNIYNLNIISIKYIFEHTFISLTNVINNICNTHHHIYVDAYTNLFHYHLNRNSYYVQLKLFQVCHIFNLFFRFQNYLMLSFNDPALDIVNFFYTYKNNIPIQKHKHKHTLNSTMVGTNKMDIQKERERHLNIKGLGKDMGNIQRPKGVSTFGTHQDNKKINSNEGNESLLRKAKNDNLNDRFEMKEGKGMINGVMKRGDNPMGGYNTMGGNNPMGGYNPMGGNNPMGGYNPMGGNNTMGGNNPMGGYNPMGGYNPMGGYNPMGGYNPMGGNTNEANAFNLPSTIKITSNDNKMRKKMKRLIFSEDDIEFFIKCKLIYNVKLDIRFLLKEKNMSICEFTKIPMPQYICYRKQTLIENNEYLFSIIHKYNYEKNNIYIISECLKNCPILEHCTDTNNLILKLKSLKMNYMSLQDQKENNLIHLINKAIDIFLSDEMTYVEFLDEFPANLSIYKFKDDKILQKSKMEQIYFDMLQNTYDKSSFFQVKWRNIALQISLNILRKKKHMNYLKKLYEKQEYIEDLIINYQHKMKKDIVTLKNAIIFVSKLYIEKPILLHSSYFKKNLFFVELKKKKHIQRTFKLPYNSSTVHIYQMKDLINNQILSNIHETLYTLVNYLTIEIFFDLNNIIKFSLILTKDQNKNIINEHTFTGSEIYSMYNSSPYILYPFFKYSKTYLCSITGLHFMHLLHNFVIDLY
Protein: Putative F-box protein At1g60370 (O80758)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MNGGEKLESIPIDLIIEIHSRLPAESVARFRCVSKLWGSMFRRPYFTELFLTRSRARPRLLFVLQHNRKWSFSVFSSPQNQNIYEKPSFVVADFHMKFSVSTFPDFHSCSGLIHFSMMKGAYTVPVVCNPRTGQYAVLPKLTRTRYENSYSFVGYDPIEKQIKVLFMSDPDSGDDHRILTLGTTEKMLGRKIECSLTHNILSNEGVCINGVLYYKASRIVESSSDDDTSDDDDDDHERSDVIVCFDFRCEKFEFIVICFYGQLINSVQLSLKQKSHQKLDLII
Protein: NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) (P00387)
Organism: Homo sapiens (Human)
Function: Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor.
Subcellular location: [Isoform 1]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:9639531}; Lipid-anchor {ECO:0000250|UniProtKB:P20070}; Cytoplasmic side {ECO:0000250|UniProtKB:P20070}. Mitochondrion outer membrane {ECO:0000305|PubMed:9639531}; Lipid-anchor {ECO:0000250|UniProtKB:P20070}; Cytoplasmic side {ECO:0000250|UniProtKB:P20070}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:9639531}.
Interaction partners:
- Cytochrome b5 type B
- Cytochrome b5
- Sulfite oxidase, mitochondrial
- Mitochondrial amidoxime-reducing component 1
- Hemoglobin subunit alpha
- Dihydroorotate dehydrogenase
- Dihydropyrimidine dehydrogenase [NADP
- Uridine 5'-monophosphate synthase
- Hemoglobin subunit beta
- Stearoyl-CoA desaturase
Sequence:
MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF
Protein: O-phospho-L-seryl-tRNA:Cys-tRNA synthase (EC 2.5.1.73) (Sep-tRNA:Cys-tRNA synthase) (SepCysS) (Q59072)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
Interaction partners:
- O-phosphoserine--tRNA
- Uncharacterized protein MJ1481
- Uncharacterized protein MJ1477
- O-phosphoseryl-tRNA
- Trk system potassium uptake protein TrkA homolog
- Uncharacterized protein MJ1676
- UPF0425 pyridoxal phosphate-dependent protein MJ0158
- L-seryl-tRNA
- UPF0056 membrane protein MJ1677
- Uncharacterized protein MJ1679
Sequence:
MDKYKNLTRSLTREFINLNPIQRGGILPKEAKKAVYEYWDGYSVCDYCHGRLDEVTCPPIKDFLEDIAKFLNMDCARPTHGAREGKFIVMHAICKEGDYVVLDKNAHYTSYVAAERAKLNVAEVGYEEEYPTYKINLEGYKEVIDNLEDKGKNVGLILLTHVDGEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVGRMPVNGKEVKADFIVASGHKSMAASAPCGILAFSEEFSDKITKTSEKFPVKEIEMLGCTSRGLPIVTLMASFPHVVERVKKWDEELKKTRYVVDELEKIGFKQLGIKPKEHDLIKFETPVLDEIAKKDKRRGFFFYDELKKRGIGGIRAGVTKEIKMSVYGLEWEQVEYVVNAIKEIVESCK
Protein: Alcohol dehydrogenase 1 (EC 1.1.1.1) (Alcohol dehydrogenase I) (ADH I) (P08843)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P06525}. Secreted {ECO:0000269|PubMed:19146970}.
Interaction partners:
- Pyruvate decarboxylase
- Aldehyde dehydrogenase
- Pyruvate decarboxylase
- Regulatory protein alcR
- catechol O-methyltransferase
- catechol O-methyltransferase
- monoamine oxidase
- catechol O-methyltransferase
- Amine oxidase
- Aldehyde dehydrogenase
Sequence:
MSIPTMQWAQVAEKVGGPLVYKQIPVPKPGPDQILVKIRYSGVCHTDLHAMMGHWPIPVKMPLVGGHEGAGIVVAKGELVHEFEIGDQAGIKWLNGSCGECEFCRQSDDPLCARAQLSGYTVDGTFQQYALGKASHASKIPAGVPLDAAAPVLCAGITVYKGLKEAGVRPGQTVAIVGAGGGLGSLAQQYAKAMGIRVVAVDGGDEKRAMCESLGTETYVDFTKSKDLVADVKAATPDGLGAHAVILLAVSEKPFQQATEYVRSRGTIVAIGLPPDAYLKAPVINTVVRMITIKGSYVGNRQDGVEALDFFARGLIKAPFKTAPLKDLPKIYELMEQGRIAGRYVLEMPE
Protein: DELLA protein 1 (MtDELLA1) (A0A396IUP1)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway (By similarity). Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes (By similarity). Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway (By similarity). Together with DELLA2, required to enable arbuscule development during arbuscular mycorrhizal (AM) symbiosis with AM fungi (e.g. Glomus versiforme) via the regulation of RAM1 which, in turn, regulates various AM genes (e.g. NSP1, NSP2, PT4, LEC5, RAM2, EXO70I, STR and RAD1).
Subcellular location: Nucleus {ECO:0000269|PubMed:24297892}.
Interaction partners:
Sequence:
MKREHQESFGGGVISNNNKTNTNHLNSSKNINFGECSSMQNTNTKQNMWREEKETNGGGMDELLAALGYKVRSSDMADVAQKLEQLEMVMGSAQEEGINHLSSDTVHYDPTDLYSWVQTMLTELNPDSSQINDPLASLGSSSEILNNTFNDDSEYDLSAIPGMAAYPPQEENTAAKRMKTWSEPESEPAVVMSPPPAVENTRPVVLVDTQETGVRLVHTLMACAEAIQQKNLKLAEALVKHISLLASLQTGAMRKVASYFAQALARRIYGNPEETIDSSFSEILHMHFYESSPYLKFAHFTANQAILEAFAGAGRVHVIDFGLKQGMQWPALMQALALRPGGPPTFRLTGIGPPQADNTDALQQVGWKLAQLAQTIGVQFEFRGFVCNSIADLDPNMLEIRPGEAVAVNSVFELHTMLARPGSVEKVLNTVKKINPKIVTIVEQEANHNGPVFVDRFTEALHYYSSLFDSLEGSNSSSNNSNSNSTGLGSPSQDLLMSEIYLGKQICNVVAYEGVDRVERHETLTQWRSRMGSAGFEPVHLGSNAFKQASTLLALFAGGDGYRVEENNGCLMLGWHTRSLIATSAWKLPQNESK
Protein: Troponin I 3 (CeTNI-3) (TnI 3) (Q9XUN9)
Organism: Caenorhabditis elegans
Function: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to muscle actomyosin ATPase activity.
Interaction partners:
- Troponin T
- Troponin T
- Troponin T, skeletal muscle
- Tropomyosin isoforms a/b/d/f
- Myosin, essential light chain
- TropoNin T
- EF-hand domain-containing protein
- Myosin regulatory light chain 1
- Myosin-2 essential light chain
- Myosin regulatory light chain 2
Sequence:
MLIEDENIRYGGAQADVEDDAARKAQERELKKAEVRKRMEEAAKKGSKKKGFLTPERKKKLRKLLMMKAAEDLKQQQMLKEQERQKTLQQRTIPLPDVDSINDQGQLLKIYEDMFARVCALEEEKFDINFGVSQTEAEINQLTIQVNDLRGKFVKPTLKKVSKYDNKFKSSGEVKEKSNFRNNLKVVKKETDLDEIMAKKKGTADGKPEWSKKEKKEEEAAPVELAAPVEPEAEPEPEAAEPAAEEPEAEEEEEEEEEEE
Protein: Uncharacterized WD repeat-containing protein C12G12.01c (Q09866)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05
- Protein transport protein sec13
- Vacuolar membrane-associated protein iml1
- Nucleoporin seh1
- Uncharacterized WD repeat-containing protein C4F8.11
- Nitrogen permease regulator 2 homolog
- Nitrogen permease regulator 3-like protein
- GTP-binding protein gtr1
- GTP-binding protein gtr2
- Uncharacterized protein C29A10.17
Sequence:
MLNRSKKRNGCYFWVNGSSDEIRYVAVKASPKVNWKTHIIWRSLKNVKCIDSFHGNNEILGAGSSTGNISLLSVKHPEFQAVVTPGYARPCNSLAFSETEHLVAGFAKSRNESSLKLWDLNSLLSDPKSSPLMQSSTLDGVSSVCYKKDTPLLLTGSTSRSVHIIDTRQQLDSVSSVNTQYYSNIVVDPFSPNYFAANSYDGDIAIFDTRYFKSDNYLQIILRNENKKPKNPQLFALKYSEWKPGQLAVLSNNSITLRQLLPCVNGNEGSANNSVFVNYEKKYPVKPNSQCSGIDFFTPSTAFPTHVQILGVINEQPKLFSVHDEVIPFSFNPYNDLIFSFKEKLYPLNSSPFNTLSDVPQFDVSEFVDENSFDSSSSCSSKVFLTTRNNSINSEDSAHEVLLSYNRVLGSDIQGTILDRVKKGYQFDSQKNSELVSDLYLKDLWSWIHLSHRQSEESLFGDTGDTDFSYQGALGIWFMDTELTSMSDVFEAKESKFLEKKILRLARDVIERLDLDIFTSIQTKRPLRQLALLACGLGMSNDDLLLEIRRLIRKNEHVKAAGLALFHGKIENVVRILSSGNELEKTISTAVAGYITSQGLSNFGSDSLWKEMSRNLSTELEDPYLRAIFAYVSNSDWRDVLDEVSLSLKDRLGIALRFLPDDDLSNYLCDLCHTTVQSGDPEGLLLTGLTPLGMELLQNYIDHTSDVQTAALIAAFVVPKKFLDKRAEDWTESYRELLNRWKLYRERAKFDIFRTELSKNHTGEITRKATEPSIRIICNFCRKPIFPFSNRNECNNLPTPIQRGVSKAGPAKHLGKSCPHCGQPLPKCSVCGFSLGDEDVPQKDDFSQKPQNYVKEVNLQKSRFGLWFSFCLNCGHGAHASHASEWFSTHTICPVPNCDCECKLK
Protein: Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3) (O14828)
Organism: Homo sapiens (Human)
Function: Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Tumor susceptibility gene 101 protein
Sequence:
MAQSRDGGNPFAEPSELDNPFQDPAVIQHRPSRQYATLDVYNPFETREPPPAYEPPAPAPLPPPSAPSLQPSRKLSPTEPKNYGSYSTQASAAAATAELLKKQEELNRKAEELDRRERELQHAALGGTATRQNNWPPLPSFCPVQPCFFQDISMEIPQEFQKTVSTMYYLWMCSTLALLLNFLACLASFCVETNNGAGFGLSILWVLLFTPCSFVCWYRPMYKAFRSDSSFNFFVFFFIFFVQDVLFVLQAIGIPGWGFSGWISALVVPKGNTAVSVLMLLVALLFTGIAVLGIVMLKRIHSLYRRTGASFQKAQQEFAAGVFSNPAVRTAAANAAAGAAENAFRAP
Protein: Katanin regulatory subunit B1 (H3BTU7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
XRAEIQNAEDYNEIFQPKNSISRTPPRRSEPFPAPPEDDAATAKEAAKPSPAMDVQFPVPNLEVLPRPPVVASTPAPKAEPAIIPATRNEPIGLKASDFLPAVKIPQQAELVDEDAMSQIRKGHDTMCVVLTSRHKNLDTVRAVWTMGDIKGHTVPHCPTPDGALFAQTSVDSAVAINDLSVVVDLLNIVNQKASLWKLDLCTTVLPQIEKLLQSKYESYVQTGCTSLKLILQRFLPLITDMLAAPPSVGVDISREERLHKCRLCYKQLKSISGLV