wanglab/gogpt-training-data huggingface dataset:
Protein: Sad1-interacting factor 2 (Sporulation protein sif2) (O74446)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for sporulation where it is believed to have a role in meiotic nuclear division.
Subcellular location: Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Localized primarily along the nuclear envelope in a punctate pattern. {ECO:0000269|PubMed:14655046}.
Interaction partners:
- Uncharacterized protein C22E12.19
Sequence:
MSNRIGPQRSTKTAAKLRLLPSTEEFDDFRRQDTGREVYSQIPQIEGSTAKRDAEHLGKRHREFLPRVTAYCTCDTFRVDLLFKFFQSRRSSHKTRPKQFDECIYSPYSYNNEETTDLLPDTLESSRGTLNRESSQESLQSIFEESGLDRNQPLFREVFCFTYGVVVLWGYTIDEEHRFLRELGRFEIEKLKIEDMEVEEFNYYITTLYQPRIFNDFIALRDASNYMIRLSISHAIAQSVKISLFEELVNETIDATKDTPQMIAETGRVNLKREEIMMAVGQLFILRININLQGSVLDSPELMWTEPQLEPIYTAARSYLEINQRVALLNQRVEVIGDLLSMLKEQITHTHDESLEWIVVILMGLLVLIALFSIVVDWKLFQ
Protein: Uncharacterized protein C16E8.12c (Q9C117)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Meiotically up-regulated gene 165 protein
- Uncharacterized protein C24B10.19c
- Histone deacetylase clr6
- Chromatin modification-related protein png2
- Transcriptional regulatory protein sds3
- Transcriptional regulatory protein rxt3
- Paired amphipathic helix protein pst1
- SWIRM domain-containing protein laf1
- Paired amphipathic helix protein pst3
- SWIRM domain-containing protein laf2
Sequence:
MAKPKKENDLDLLIQLADALEAIPGDLSKNFTEVRFLEAELKDVYSQALSSIDDLLNRDTSVERRNLVARNLSLLLKSDDVQTRKKSHIAMYAEAITHSNVLRLEHCYQKMEMKLPNFFIPFTPEVIKEQKTSRPIRASRRRANLRNRRAKELLAAENASEEGDKKQIITDSGKLPETEELTETTNEDLDIKQFSPYSSESSANVSSYNKS
Protein: MKRN3 protein (Makorin ring finger protein 3) (Q6NSB6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPVAPVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRDIC
Protein: BBSome complex member BBS1 (Bardet-Biedl syndrome 1 protein homolog) (Q3V3N7)
Organism: Mus musculus (Mouse)
Function: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly (By similarity). Plays a role in olfactory cilium biogenesis/maintenance and trafficking and is essential for the localization of the BBSome complex in the olfactory sensory neurons cilia.
Subcellular location: Cell projection, cilium membrane {ECO:0000250|UniProtKB:Q8NFJ9}. Cytoplasm {ECO:0000250|UniProtKB:Q8NFJ9}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000250|UniProtKB:Q8NFJ9}.
Interaction partners:
- Tetratricopeptide repeat protein 8
- BBSome complex member BBS5
- BBSome complex member BBS2
- BBSome complex member BBS4
- BBSome complex member BBS7
- Protein PTHB1
- Rab-3A-interacting protein
- BBSome interacting protein 1
- BBSome complex assembly protein BBS10
- Leucine zipper transcription factor-like protein 1
Sequence:
MAAASSSDSDSGRAESNEANSKWLDAHYDPMANIHTFSSCLSLADLHGDGEYKLVVGDLGPGGQQPRLKVLKGPTVLTESPLPALPASAATFLMDQHEPRTPALALASGPCVYVYKNLRPYFKFSLPQLPPNPLEQDVWNQAKEDQIDPLTLKEMLEDIREKADVPLSVQSLRFLQLELSEMEAFVNQHKSKVIKRQTVITTMTTLKKNLADEDAASCLVLGTESKELLVLDPEAFTILAKMSLPSVPVFLEVSGQFDVEFRLTAACRNGSIYILRRDSKHPKYCIELSAQPVGLVRVHKVLVVGSTQESLHGFTHKGKKLWTVQMPAAILTMNLLEQRSRGLQAVMAALANGEVRIYRDKALLNVIHAPDAVTSLCFGRYGREDNTLIMTTRGGGLIIKILKRTAVFVEGTGEVGPPLAQTTKLSVPRKTRLYVDQTLREREAGTAMHRTFQTDLYLLRLRAARAYVQALESSLSPMSTTAREPLKLHAVVQGLGPTFKLTLHLQNTSTARPVLGLHVCFLYNKALYALPQAFFKVPLLVPGLSYPLETFVESLSSKGISDMIKVLVLREGQSAPLLSAHINMPVSEGLAAA
Protein: Coiled-coil and C2 domain-containing protein 1-like (Lethal (2) giant discs 1 protein) (Q9VKJ9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Negative regulator of the Notch signaling pathway, acting to restrict the activity of Notch to the dorsoventral (D/V) boundary of the wing imaginal disk. Also causes negative regulation of Notch during vein, eye, and bristle development. Acts by targeting Notch for endosomal degradation or recycling.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17084358, ECO:0000269|PubMed:17088062}. Cytoplasm, cytosol {ECO:0000269|PubMed:17084357, ECO:0000269|PubMed:22389409}. Apicolateral cell membrane {ECO:0000269|PubMed:17084357, ECO:0000269|PubMed:17084358}; Peripheral membrane protein {ECO:0000269|PubMed:17084357}; Cytoplasmic side {ECO:0000305}. Cytoplasm, cell cortex {ECO:0000269|PubMed:17084357, ECO:0000269|PubMed:17084358}. Endosome {ECO:0000269|PubMed:33349255}. Note=Punctate localization in the cell cortex could indicate vesicle association (Probable). Apico-lateral membrane concentration in polarized epithelial and imaginal disk cells but not in asymmetrically dividing neuroblasts (PubMed:17084357, PubMed:17084358). {ECO:0000269|PubMed:17084357, ECO:0000269|PubMed:17084358, ECO:0000305|PubMed:17084357}.
Interaction partners:
- Charged multivesicular body protein 4
- GH14561p
- IST1 homolog
- RH72336p
- Vacuolar protein sorting 20, isoform A
Sequence:
MFSRKKPEPAKRRQHDLSQFGLTEIPDDFDPSAGYGEDDGGDSDLEAELAAITGGEGAKPKPKPKAKLLPASDLDKMIADSLRDVSDDDDDDNLESDPDLLGELSGIGGLEEAEEEEPVAQPPAASEEPVQTFLPTTTVDTLSIIKQRLEMYKQAEANAKTAGDSGKARRFGRGLKTLKDLHRQAAAGKSINVDDIPPEVSVKPIGGQAPPVPAEESPAPSTPASPPPVPSRAAPDPPTPGTPVEPTTSVAPTSPPNPLVTQMRSRQTDYKAAALQSKRSGDISTALQFLKVVKQFDVVIKMCEDGQEVDLSDMPPPPAEFLEFLKKMQEEAAAEAVAEPTAAPEPTPVAPAPVLAAATNMLEALQQRLEKYQSVEAAAKAENNSGKARRFGRIVKQYEDAIKLYKAGKPVPYDELPVPPGFGPLPTADAAPVAPTPSLPTSPTSPPPTASTSAGGTPSSSSATTPTAPRKAPSPPKPKELTTRTSGNQQKNNIAEQQMKLLLERQKEFKLAAIEAKKAGEIDQAKEYLKIFKGFDSLLNAASSGLPVDLSTLPVPPSQRDNLEASFAIVSAEECDPTDDICEIGVRMEEQLAKQLMMCKNTRDHHKAMGDVAGMNRFENLALTVQKDLDLVRYSKRKNEPLPKFHYEKRSFNIVHCNTDLTDSELEIVVVRGISYNVANPKDVDTYVRVEFPLLNDESFKTKTNVIRDTSSPDYDERFKVDIQRTNRQFQRIFKRHGVKFEIYSRGGFLRSDTLIGTVNVKLQPLETKCEIHDTYDLMDGRKQVGGKLEVKIRVRNPILTKQMEHITEKWLVLDA
Protein: Coiled-coil domain-containing protein 28A (CCRL1AP) (Q8IWP9)
Organism: Homo sapiens (Human)
Interaction partners:
- Epithelial cell-transforming sequence 2 oncogene-like
Sequence:
MPRAEPRATLGEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAVGSLRVAEGGPNTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTASDSNLDRLLSDLEELNSSIQKLHLADAQDVPNTSAS
Protein: Apoptosis-stimulating of p53 protein 2b (Tumor protein p53-binding protein, 2b) (Q1LXN7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFLTVYLSNSDKHFTELPITPETLCRDVLDMCKEPGEVDCYLAEMWRGSERVIGDSERIIEVLQRWGQQRAEVRFFLRHDRAPGHDTGGHRTPESLAKRSNAVKDRLMENGMAAPHMDITLSELQEMASRQQQQINAQQQLLATKEQRLRFLKLQDQRQQQQQVSEQEKLRQLRENAENQEAKLRRVRALKGQVEQKRISNSKLVEEIEQMNGLFQQKQRELVVAVSRVEELSRQLDVLRSGKMDMPHEAGPSSSGELERLYKELQLRNKLNQEQSAKLQQQRENLNKRNVEMAAMDKRVAELRERLWKKKAALQQKENLPQPSEGQNPQSVGPSRVAAVGPYIQTTPAPPLPPKQEILVKPAYPDGTATLPKPLPKPTTGGFLTGKISKISDLFSSTETSKSSHVHSSTLPRMTSHGSQEKDPEVDLRPPPLPLRKNQSSEDLLRDSQSAGRTFEKVPPPVPSKPKPALSGQSTFSKLPYSTGTFPGKARSANQKPPMPLPSHNNTLPLPLPPKPDTLPAATVRPFTSDTLAGKDTSTPTTLHKPQTVAASSIYSMYTQQSTLGKGYQGQSTLTRSQPRLYGKPVIPSSVGQQSFIQDFSHIEKICGLDGDQVDQGSSNTAPASSSVEGQEAERVPRPLSPTKLLPFLSNSHRLQSDVDLEALRKRLHNAPRPLKKRGSITESEGPGGPNIQKLLYQKTTLAAMETIAPAAFFPAEGEDGCRPVPNESTRPQEGHHDNTIPECEREEEELTPPPLPPRSPILDDNSNFSTGLNEPQLKEEQEVYGPAAPEPYVEEYPPYPPPPYPSMTEQEGPGEDSINMKAPEVTGQVMLPPGKRTNLRKTGSERINHGMRVRFNPLALLLDSSLEGEYDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQYGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVYAMTYSDLQTAADKCEEMEEGYAQCSQFLYGVQEKMGIMNRGVVYALWDYDGESPDELSFKEGDCLTVLRREDGEETEWWWARCADNEGYIPRNLLGLYPRIKPRQRSLA
Protein: GH12991p (Q95T84)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDHRAEQETQEINAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFGNIWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTSTCHMSITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGEDKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGAAALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEFHNRKYKVFLQLLENQRQYRRIMQADTK
Protein: 18.1 kDa class I heat shock protein (HSP 18.1) (P19243)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Subcellular location: Cytoplasm.
Interaction partners:
Sequence:
MSLIPSFFSGRRSNVFDPFSLDVWDPLKDFPFSNSSPSASFPRENPAFVSTRVDWKETPEAHVFKADLPGLKKEEVKVEVEDDRVLQISGERSVEKEDKNDEWHRVERSSGKFLRRFRLPENAKMDKVKASMENGVLTVTVPKEEIKKAEVKSIEISG
Protein: ABI gene family member 3 (New molecule including SH3) (Nesh) (Q9P2A4)
Organism: Homo sapiens (Human)
Function: May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11956071}. Note=Colocalizes with PAK2 at leading edge of cells.
Interaction partners:
- Target of Nesh-SH3
- Cytoplasmic FMR1-interacting protein 1
- Nck-associated protein 1
- Nck-associated protein 1-like
- Protein BRICK1
- Actin-binding protein WASF2
- Actin-binding protein WASF1
- Cytoplasmic FMR1-interacting protein 2
- Actin-binding protein WASF3
- Abl interactor 2
Sequence:
MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC
Protein: Galectin-3-binding protein (Cyp-C-associated protein) (CyCAP) (Lectin galactoside-binding soluble 3-binding protein) (Protein MAMA) (Q07797)
Organism: Mus musculus (Mouse)
Function: Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q08380}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:8119883}.
Interaction partners:
- Galectin-3
- Soluble calcium-activated nucleotidase 1
- Galectin-9
- Ubl carboxyl-terminal hydrolase 18
- Interferon-induced protein with tetratricopeptide repeats 3
Sequence:
MALLWLLSVFLLVPGTQGTEDGDMRLVNGASANEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALGRAAFGPGKGPIMLDEVECTGTESSLASCRSLGWMVSRCGHEKDAGVVCSNDTTGLHILDLSGELSDALGQIFDSQQGCDLFIQVTGQGYEDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQDYCGRLFATLLPQDPTFHTPLDLYAYARATGDSMLEDLCVQFLAWNFEPLTQSESWSAVPTTLIQALLPKSELAVSSELDLLKAVDQWSTETIASHEDIERLVEQVRFPMMLPQELFELQFNLSLYQDHQALFQRKTMQALEFHTVPVEVLAKYKGLNLTEDTYKPRLYTSSTWSSLVMASTWRAQRYEYNRYNQLYTYGYGSVARYNSYQSFQTPQHPSFLFKDKQISWSATYLPTMQSCWNYGFSCTSNELPVLGLTTSSYSNPTIGYENRVLILCGGYSVVDVTSFEGSKAPIPTALDTNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDMV
Protein: L-cystine transport system ATP-binding protein TcyN (EC 7.4.2.12) (P37774)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex TcyJLN involved in L-cystine import. This high affinity cystine transporter is involved in resistance to oxidative stress by forming a L-cysteine/L-cystine shuttle system with the EamA transporter, which exports L-cysteine as reducing equivalents to the periplasm to prevent the cells from oxidative stress. Exported L-cysteine can reduce the periplasmic hydrogen peroxide to water, and then generated L-cystine is imported back into the cytoplasm via the TcyJLN complex. Functions at low cystine concentrations. The system can also transport L-cysteine, diaminopimelic acid (DAP), djenkolate, lanthionine, D-cystine, homocystine, and it mediates accumulation of the toxic compounds L-selenaproline (SCA) and L-selenocystine (SeCys). Could also facilitate threonine efflux. Responsible for energy coupling to the transport system (Probable).
Subcellular location: Cell inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- L-cystine transport system permease protein TcyL
- L-cystine-binding protein TcyJ
- Glutamine transport system permease protein GlnP
- Glutamate/aspartate import permease protein GltK
- Glutathione/L-cysteine transport system ATP-binding/permease protein CydD
- Oligopeptide transport system permease protein OppC
- Molybdenum transport system permease protein ModB
- High-affinity branched-chain amino acid transport system permease protein LivM
- Glutamate/aspartate import permease protein GltJ
- D-cysteine desulfhydrase
Sequence:
MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGAAKALFADPEQPRTRQFLEKFLLQ
Protein: Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Protein SOH1) (dSOH1) (Q8IH24)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for activated transcription of the MtnA gene.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 11
- Cyclin-dependent kinase 8
- Mediator of RNA polymerase II transcription subunit 19
Sequence:
MAKMYGKGKTAIESEELQKRRWQIELEFVQCLSNPNYLNFLAQRGFFKDQSFINYLKYLQYWKEPDYAKYLMYPMCLYFLDLLQYEHFRREIVNSQCCKFIDDQAILQWQHYTRKRIKLIENVTAAQQQQQQLQQQQQQANGMEAATGGESAAPTPNVNGSASTADSQQTSSALQPVQAQPGNPQQQQQINGVASGANIKLELN
Protein: Photosystem I assembly protein Ycf4 (P56788)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Seems to be required for the assembly of the photosystem I complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00437}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00437}.
Interaction partners:
- Potassium/proton antiporter CemA
- Photosystem I assembly protein Ycf3
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I reaction center subunit VIII
- Photosystem II D2 protein
- Photosystem II reaction center protein H
- Cytochrome b559 subunit alpha
- Photosystem I P700 chlorophyll a apoprotein A1
- Photosystem II reaction center protein K
- Photosystem II CP47 reaction center protein
Sequence:
MSWRSESIWIEFITGSRKTSNFCWAFILFLGSLGFLLVGTSSYLGRNVISLFPSQQIIFFPQGIVMSFYGIAGLFISCYLWCTILWNVGSGYDLFDRKEGIVRIFRWGFPGKSRRIFLRFFMKDIQSIRIEVKEGVSARRVLYMEIRGQGAIPLIRTDENFTTREIEQKAAELAYFLRVPIEVF
Protein: Protein P3 (Protein III) (Q9XJR6)
Organism: Pseudoalteromonas phage PM2 (Bacteriophage PM2)
Subcellular location: Virion membrane {ECO:0000305|PubMed:12134022, ECO:0000305|PubMed:7408847}; Single-pass membrane protein {ECO:0000305|PubMed:12134022, ECO:0000305|PubMed:7408847}. Note=Part of the capsid inner membrane. Deeply embedded in the lipid bilayer. About 20% of the molecule extends to the exterior. {ECO:0000305|PubMed:18775333}.
Interaction partners:
Sequence:
MNTSVPTSVPTNQSVWGNVSTGLDALISGWARVEQIKAAKASTGQGRVEQAMTPELDNGAAVVVEAPKKAAQPSETLVFGVPQKTLLLGFGGLLVLGLVMRGNK
Protein: Putative aminopeptidase C13A11.05 (EC 3.4.11.-) (Q09735)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Cys-Gly metallodipeptidase dug1
- Glutathione synthetase large chain
- Glutathione hydrolase proenzyme 1
- Glutathione hydrolase proenzyme 2
- Glutathione-specific gamma-glutamylcyclotransferase
- Putative glutamate--cysteine ligase regulatory subunit
- Glutamate--cysteine ligase
- Probable proline dehydrogenase, mitochondrial
- Pyrroline-5-carboxylate reductase
- Aspartate aminotransferase, cytoplasmic
Sequence:
MKGLGLSTRTFNWSSLSSILLPRIPLATTKADSLILAVRHDKQVFSEDYRQVVDQYFETSPKKNDIRLFWNTQGFVRLAIVQLEENVSEKSVRSAAAEAAKILKSNGAKSIAVDGMGFPKDAALGAALATYDFSLRRDHLSVYQDEKVVEKENLFTSPAPERLTFQLLSNTSEKKTATAEENAFKVGLIEAAAQNLARSLMECPANYMTSLQFCHFAQELFQNSSKVKVFVHDEKWIDEQKMNGLLTVNAGSDIPPRFLEVQYIGKEKSKDDGWLGLVGKGVTFDSGGISIKPSQNMKEMRADMGGAAVMLSSIYALEQLSIPVNAVFVTPLTENLPSGSAAKPGDVIFMRNGLSVEIDNTDAEGRLILADAVHYVSSQYKTKAVIEASTLTGAMLVALGNVFTGAFVQGEELWKNLETASHDAGDLFWRMPFHEAYLKQLTSSSNADLCNVSRAGGGCCTAAAFIKCFLAQKDLSFAHLDIAGVMDKQLNSWDCDGMSGRPVRTIIEVARKY
Protein: Paired box protein Pax-3 (HuP2) (P23760)
Organism: Homo sapiens (Human)
Function: Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10.
Subcellular location: Nucleus {ECO:0000269|PubMed:21965087}.
Interaction partners:
- Transcription factor SOX-10
- Myogenic factor 5
- Myoblast determination protein 1
- Myogenin
- Forkhead box protein O1
- Nuclear receptor coactivator 1
- Homeobox protein SIX1
- Paired box protein Pax-7
- Myogenic factor 6
- Microphthalmia-associated transcription factor
Sequence:
MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF
Protein: Probable L-type lectin-domain containing receptor kinase I.5 (LecRK-I.5) (EC 2.7.11.1) (Q9M1G4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MSKGLFLIWLISSFHLISFSTSSKDTSFVFNGFGQSNLALDGSATLLPNGLLQLAKDSQHQMGHAFIKKPIDFSSSKPLSFSTHFVCALVPKPGFEGGHGITFVISPTVDFTRAQPTRYMGIFNASTNGSPSSHLFAVELDTVRNPDFRETNNNHIGIDVNNPISVESAPASYFSKTAQKNVSINLSSGKPIQVWVDYHGNVLNVSVAPLEAEKPSLPLLSRSMNLSEIFSRRRLFVGFAAATGTSISYHYLLGWSFSTNRELSQLLDFSKLPQVPRPRAEHKKVQFALIIALPVILAIVVMAVLAGVYYHRKKKYAEVSEPWEKKYGTHRFSYKSLYIATKGFHKDRFLGRGGFGEVYRGDLPLNKTVAVKRVSHDGEQGMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDDQSPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGNAATTAAVGTVGYMAPELITMGASTITDVYAFGVFLLEVACGRKPVEFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLSGNLPLPDFSPYTLGIGSFTPVVVDAASLTVSFTSRNWSAPSASSSSANNSKDHEQPLEFKS
Protein: Glycerate 2-kinase (GCK) (EC 2.7.1.165) (2-phosphoglycerate forming glycerate kinase) (Q6KZ25)
Organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)
Function: Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also partially utilize GTP, CTP or UTP as phosphate donor.
Interaction partners:
- Enolase
- NAD-dependent aldehyde dehydrogenase
- D-glyceraldehyde dehydrogenase
- Phosphoglycerate mutase
- Phosphoglycerate mutase/fructose-2,6-bisphosphatase
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
- Pyruvate kinase
- Bifunctional phosphoglucose/phosphomannose isomerase
- Transcriptional repressor/ROK family
- Glucokinase
Sequence:
MIENYNDIAITDTRRKILNIIDKTLIAMDPENAIKNFIEKNNIKFDSKRIFLIGFGKAAFKMYSGIRPFILKDLVYASIIVPDDEKTNDYNELRILRGTHPFTGDLSVSSSISMLSGLKNLNENDLVIVLISGGGSSLFEIPEDGINIDDIKNISKTMMDKGCDIYELNMVRSMLSKVKGGKLATMLYPARVISFIISDVKNDDLSIIASGPLTRIDYRIEDLMETIKKYLGNDERIKMYRNIDDIYFNNVKQYIILKNRDFLDYIYSNINDDAVNLGSNFSGNVEDLSLILHNILKNIYSSKRKPFYFMLGGETTVDVKGHGSGGRNQELVLRFMKNSSNSEVYTIASFGTDGIDGVSPAAGGIVDSDHEIDNINEYLNRNDSYNLLIKNHGAIITGRTGNNVSDIIIGLYYNK
Protein: SERTA domain-containing protein 1 (CDK4-binding protein p34SEI1) (SEI-1) (p34(SEI-1)) (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (Q9UHV2)
Organism: Homo sapiens (Human)
Function: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Interaction partners:
- Cell division cycle-associated protein 4
- Cyclin-dependent kinase 4
- Replication protein A 32 kDa subunit
- CST complex subunit STN1
- Cyclin-dependent kinase inhibitor 2A
- SERTA domain-containing protein 4
Sequence:
MLSKGLKRKREEEEEKEPLAVDSWWLDPGHTAVAQAPPAVASSSLFDLSVLKLHHSLQQSEPDLRHLVLVVNTLRRIQASMAPAAALPPVPSPPAAPSVADNLLASSDAALSASMASLLEDLSHIEGLSQAPQPLADEGPPGRSIGGAAPSLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDNELWAPASEGLKPGPEDGPGKEEAPELDEAELDYLMDVLVGTQALERPPGPGR
Protein: Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160) (Q61543)
Organism: Mus musculus (Mouse)
Function: Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils).
Subcellular location: Cell membrane {ECO:0000269|PubMed:9099943}; Single-pass type I membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:9099943}; Single-pass type I membrane protein {ECO:0000255}. Golgi outpost {ECO:0000250|UniProtKB:Q62638}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q62638}. Note=Golgi and microvilli on the cell surface (PubMed:9099943). Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). {ECO:0000250|UniProtKB:Q62638, ECO:0000269|PubMed:9099943}.
Interaction partners:
- E-selectin
- P-selectin
- P-selectin glycoprotein ligand 1
- Vascular cell adhesion protein 1
Sequence:
MAVCGRVRGMFRLSAALPLLLLAAAGAQNGHGQGQGPGTNFGPFPGQGGGGSPAGQQPPQQPQLSQQQQQPPPQQQQQQQQQSLFAAGGLPARRGGAGPGGTGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTTDPKFESVAREVCKSTISEIKECAEEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIFSDYRLICGFMDDCKNDINLLKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVSELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKVVRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSELMPPGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCSEKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKSDIKNYCSTVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRLDPQLQLHCSDEIANLCAEEAAAQEQTGQVEECLKVNLLKIKTELCKKEVLNMLKESKADIFVDPVLHTACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPADGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR