wanglab/gogpt-training-data huggingface dataset:
Protein: Probable LRR receptor-like serine/threonine-protein kinase RPK1 (EC 2.7.11.1) (Protein TOADSTOOL 1) (Receptor-like protein kinase 1) (Q9ZRF9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the main abscisic acid-mediated (ABA) signaling pathway and in early ABA perception. Together with RPK2, required for pattern formation along the radial axis (e.g. the apical embryonic domain cell types that generate cotyledon primordia), and the apical-basal axis (e.g. differentiation of the basal pole during early embryogenesis).
Subcellular location: Cell membrane {ECO:0000269|PubMed:15772289, ECO:0000269|PubMed:17543866, ECO:0000269|PubMed:18158146}; Single-pass type I membrane protein {ECO:0000269|PubMed:15772289, ECO:0000269|PubMed:17543866, ECO:0000269|PubMed:18158146}.
Interaction partners:
- Calmodulin-4
Sequence:
MKLLGLVFLLFNLFMFSFSRKLLTESGGGLHDEAALLKLKSSFLDPNGVLSSWVSDSSSNHCSWYGVSCNSDSRVVSLILRGCDELEGSGVLHLPDLSSCSSSKRRLGGVISPVVGDLSEIRVLSLSFNDLRGEIPKEIWGLEKLEILDLKGNNFIGGIRVVDNVVLRKLMSFEDEDEIGPSSADDDSPGKSGLYPIEIASIVSASVIVFVLLVLVILFIYTRKWKRNSQVQVDEIKEIKVFVDIGIPLTYEIIVRATGYFSNSNCIGHGGFGSTYKAEVSPTNVFAVKRLSVGRFQGDQQFHAEISALEMVRHPNLVMLIGYHASETEMFLIYNYLSGGNLQDFIKERSKAAIEWKVLHKIALDVARALSYLHEQCSPKVLHRDIKPSNILLDNNYNAYLSDFGLSKLLGTSQSHVTTGVAGTFGYVAPEYAMTCRVSEKADVYSYGIVLLELISDKRALDPSFSSHENGFNIVSWAHMMLSQGKAKEVFTTGLWETGPPDDLVEVLHLALKCTVDSLSIRPTMKQAVRLLKRIQPSRL
Protein: Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (p60) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] (Q9YH58)
Organism: Gallus gallus (Chicken)
Function: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:9677386}. Golgi apparatus {ECO:0000269|PubMed:9677386}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:O95954}. Note=More abundantly located around the mother centriole. {ECO:0000250|UniProtKB:O95954}.
Interaction partners:
- Uncharacterized protein.
- Methylenetetrahydrofolate dehydrogenase
- Trifunctional purine biosynthetic protein adenosine-3
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase
- Trifunctional purine biosynthetic protein adenosine-3
- Methylenetetrahydrofolate dehydrogenase
- 5-formyltetrahydrofolate cyclo-ligase
- Probable imidazolonepropionase
- Uncharacterized protein.
- Dihydrofolate reductase
Sequence:
MAKLVECVPNFSEGCNKEVIEALGRAISQTPGCTLLDVDAGASTNRTVYTFVGTPEAVVEGALSAARMAWELIDMSRHKGEHPRMGALDVCPFVPVMNISMEECVICAHVFGQRLSEELGVPVYLYGEAARQESRRTLPAIRAGEYEALPKKLEKPEWVPDFGPPAFVPQWGATVTGARTFLIAYNINLLCTKELAHRIALNIREQGRGADQPGSLKKVQGIGWYLEEENIAQVSTNLLDFETTPLHAVYEEVCYNAEALKLPVVGSQLVGLVPKKAMLDAAEFYIKKEKLFILEEEHKIKLVVSRLGLDSLSPFNPRERIIEYLVQAGQEDKGLVTKPLGAFVRAVGGRSAAPGGGSVAATAASLGAALGCMVGLMSYGKRQFEQLDSIMRNVIPPLHQAMDELVAMVDADSRAFSSYMEAMKLPKSTPEERERRVVAMQQGLKTAVEVPCTLAVKVNNLWSSLKMLAHHGNLACKSDLQVGAKMLEAAVFGAYFNVMINLKDITDEKFKTETSQMVTRLLEEAKQGSALVLALLEKREA
Protein: Serine/threonine-protein kinase CLA4 (EC 2.7.11.1) (Q5APR8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Ser/Thr kinase required for wild-type filamentous growth, chlamydospore formation, and virulence in mouse systemic infection.
Interaction partners:
- Cell division control protein 42 homolog
- Rga2p
- Phosphatidylinositol-3-phosphate-binding protein
- G protein subunit beta
- mitogen-activated protein kinase kinase kinase
- Serine/threonine-protein kinase CST20
- Guanine nucleotide-binding protein subunit gamma
- Rho family GTPase
- Ste50p
- High osmolarity signaling protein SHO1
Sequence:
MTSIYTSDLKNHRRAPPPPNGAAGSGSGSSSGSGSGSGSGSGSGSLTNIVTSSNSLGVTANQTKPIQLNINSSKRQSGWVHVKDDGIFTSFRWNKRFMVINDKTLNFYKQEPYSSDGNSNSNTPDLSFPLYLINNINLKPNSGYSKTSQSFEIVPKNNNKSILISVKTNNDYLDWLDAFTTKCPLVQIGENNSGVSSSHPHLQIQHLTNGSLNGNSSSSPTSGLSSSSVLTGGNSGVSGPINFTHKVHVGFDPASGNFTGLPDTWKSLLQHSKITNEDWKKDPVAVIKVLEFYSDINGGNSAAGTPIGSPMINSKTNNNNNDPNNYSSAKNNVQEANLQEWVKPPAKSTVSQFKPSRAAPKPPTPYHLTQLNGSSHQHTSSSGSLPSSGNNNNNNNSTNNNNTKNVSPLNNLMNKSELIPARRAPPPPTSGTSSDTYSNKNHQDRSGYEQQRQQRTDSSQQQQQQQKQHQYQQKSQQQQQQPLSSHQGGTSHIPKQVPPTLPSSGPPTQAASGKSMPSKIHPDLKIQQGTNNYIKSSGTDANQVDGDAKQFIKPFNLQSKKSQQQLASKQPSPPSSQQQQQKPMTSHGLMGTSHSVTKPLNPVNDPIKPLNLKSSKSKEALNETSGVSKTPSPTDKSNKPTAPASGPAVTKTAKQLKKERERLNDLQIIAKLKTVVNNQDPKPLFRIVEKAGQGASGNVYLAEMIKDNNRKIAIKQMDLDAQPRKELIINEILVMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKKHIIHRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRNKRATMVGTPYWMAPEVVKQKEYDEKVDVWSLGIMTIEMIEGEPPYLNEEPLKALYLIATNGTPKLKKPELLSNSIKKFLSICLCVDVRYRASTDELLEHSFIQHKSGKIEELAPLLEWKKQQQKHQQHKQETSDTGFA
Protein: Acetate permease A (Q5BC91)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MASTETSEKYDLKNTITNADTPSPPSEQQLAPESSHLDYATSGGLSHMLTAESRLPAFGGAFQPGLYRPPKKIANPAPLGLCAFGLSAFLLGAVQMKVLNITVPSILVAPAFAYGGLVQLLAGMWEMAIGNTFGATVLSSYGGFWISVGIIFTPGGFNIMGSLIEASGGNTDMFNDCLGLFLLAWFIFTVIMTLCTFKSTLAFCSLFIFADIALLLLGVAFIHRDAEGMPNESLCKAGGFFAILCAFLCWYNAFAGLAEPSNSYFVPPVVHFPWSEQGRKSRRPAPVECTESV
Protein: Fumarylpyruvate hydrolase (EC 3.7.1.20) (Naphthalene degradation protein K) (O86042)
Organism: Ralstonia sp
Function: Involved in the catabolism of gentisate (2,5-dihydroxybenzoate) a key intermediates in the aerobic pathways for the metabolism of a large number of aromatic compoun such as naphthalene. Catalyzes the hydrolytic cleavage of fumarylpyruvate to form fumarate and pyruvate.
Interaction partners:
Sequence:
MGRPVDKSVEQAFYFTKSPQTLVESGATVAYPPRTSNYHYEMELVLAIGKPGFRVSEDQAHELIYGYAAGLDMTRRDLQLVARDKGRPWDTGKDIEEGSVCSEIVPMQGVVVEQGAIALEVNGQTKQSSNVDKLIWNVREIIADLSTYYHLQPGDLIYTGTPEGVGAVVAGDKIIGRVEGIAEISLTVGPAE
Protein: PAS domain-containing protein tyrosine kinase family protein (F4HVH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At2g17975
- Zinc finger
Sequence:
MENPNPPAEKLLKKIRELEESQEDLKREMSKLKVSAEIKRRSHSSSPKRPSRRNSGEGTPLWRKTGAASFRHASPLRKESHSKDGVAGGGDGPSAGKFTDKQYLNILQSMAQAVHVFDLNGQIIFWNSMAEKLYGFSAAEALGKDSINILVDGQDAAVAKNIFQRCSSGESWTGEFPVKNKMGERFSVVTTISPFYDDDGLLIGIICITNDSALFQRPRVPPAKNRWQEGDSSFCRGTNGVASRLGFDSKEAVVSKLGLDSQQPIQAAIASKISDLASKVGNKVRSKMRAGDNNASHPEGGNGGSHQSDQGFFDAAFSDQREDAETNDASTPRGNLIQSPFGVFLCNDDKSSSKASGESNDENDRNSVVPKKLTSKTEEWMVKKGLSWPWKGNEREGLERRNAHSVWPWVHNEQQKEEAHHSNSYNSVKSESLASESNKPANNENMGSVNVNSASSASSCGSTSSSVMNKVDMDSDCLDYEILWEDLTIGEQIGQGSCGTVYHGLWFGSDVAVKVFSKQEYSEEIITSFKQEVSLMKRLRHPNVLLFMGAVASPQRLCIVTEFLPRGSLFRLLQRNKSKLDLRRRIHMASDIARGMNYLHHCSPPIIHRDLKSSNLLVDRNWTVKVADFGLSRIKHETYLTTNGRGTPQWMAPEVLRNEAADEKSDVYSFGVVLWELVTEKIPWENLNAMQVIGAVGFMNQRLEVPKDVDPQWIALMESCWHSEPQCRPSFQELMDKLRELQRKYTIQFQAARAASIDNSSLKEK
Protein: Cilia- and flagella-associated protein 90 (A4QMS7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:36191189}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9DAR0}.
Interaction partners:
- Piercer of microtubule wall 1 protein
- Enkurin
- Cilia- and flagella-associated protein 276
- Cilia- and flagella-associated protein 52
- Cilia- and flagella-associated protein 53
- Protein Flattop
- Cilia- and flagella-associated protein 161
- Tektin-1
- Cilia- and flagella- associated protein 210
- Cilia- and flagella-associated protein 107
Sequence:
MEDDEEETTASTLRGKPRPPPVSAQSAFSYIPPRRLDPKEHSYYYRPARTGIISLYDCIFKRRLDYDQKLHRDDREHAKSLGLHVNEEEQERPVGVLTSSVYGKRINQPIEPLNRDFGRANHVQADFYRKNDIPSLKEPGFGHIAPS
Protein: Low-density lipoprotein receptor class A domain-containing protein 4 (O15165)
Organism: Homo sapiens (Human)
Function: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
Subcellular location: Early endosome membrane {ECO:0000269|PubMed:24627487}; Single-pass membrane protein {ECO:0000269|PubMed:24627487}.
Interaction partners:
- TSC22 domain family protein 1
- Mothers against decapentaplegic homolog 2
Sequence:
MPEAGFQATNAFTECKFTCTSGKCLYLGSLVCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQIIIIVVVVTVMVVVIVCLLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASEIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVPIKGKDRKPGNLV
Protein: 5'-3' exoribonuclease 1 (mXRN1) (EC 3.1.13.-) (Protein Dhm2) (Strand-exchange protein 1 homolog) (P97789)
Organism: Mus musculus (Mouse)
Function: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA. Plays a role in replication-dependent histone mRNA degradation (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9049243}. Note=Discrete foci at the inner surface of the cell membrane.
Interaction partners:
- m7GpppN-mRNA hydrolase
- Protein PAT1 homolog 1
- mRNA-decapping enzyme 1A
- U6 snRNA-associated Sm-like protein LSm1
- Enhancer of mRNA-decapping protein 3
- 3'-5' RNA helicase YTHDC2
- 5'-3' exoribonuclease 2
- Protein PAT1 homolog 2
- Trinucleotide repeat-containing gene 6A protein
- H/ACA ribonucleoprotein complex subunit DKC1
Sequence:
MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGAAAEEAKNCKEKRKPKGQENSLSWAALDKSEGEGVASRDNFEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLANQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIRSISTLKIHFELGKPFKPFEQLLAVLPSASKNLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDETRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFTYSSPWPEKFPAIERCCTRYKMISLDAWRVDINKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENLMLEISVNAEPDELRIENIASAVLGKAVFVNWPHLEEARVVAVSDGETKFYIEEPPGTQKVYLGKTAPPSKVIQLTDKEQSNWTKEIQGISEQYLRRKGIIINETSAVVYAQLLTGRKYQISQNGEVRLEKQWSKQILPFVYQTIVKDIRAFDSRFSNIKTLDDLFPPRTMVFMLGTPYYGCTGEVQDSGDLITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYIERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKSNKKVRVTVKPHLMYRPLEQQHGVIPDRDAEFRLFDRVVNVRESFSVPVGLRGTVIGIKGASREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPSVSHCSAAPSGHLGGLNHSPQSPFLPTQVPTKGDDEFCNIWQSLQGAGKTQHLQPTVQEKGAVLPQEISQVTEGHKSGFTDHSVRHQQRKHDSQRKFKEEYKSPKAECQSQKLSSKQTSGGSARCSIKLLKRNESPGTSEAQKVVTSYPNAVHKPPSGIENFLASLNLSKENEAQLPHHGEPPDEADLSPQSFAMKGTRMLKEILKIDSPDTRDSKNDMKKSDNEATVSSRRDERGVSAHPKPTCHMNKPHGTNEFQNVASVDSVCWPGQMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVCQVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVSFPLPPPIFTNYPPAVPPGAVPPVFTQPTANIMPSSSHLFGSVSWRPPVPVAGNAFHYPSYPGTMPLAGGVPGGVHSQFIPLQVTKKRVANRKNFENKEAQSSQATPLQTNKPGSSEATKMTPQESPPASSSSSQAAQPVSSHVETASQGHVGSQPRSAPSSSKRKSRKLAVNFSVSKPSE
Protein: Integrin beta (E7FCN5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU000633}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU000633}.
Interaction partners:
- Talin 1.
- Si:dkey-32n7.4
- Zmp:0000001082
- Junctional adhesion molecule A
- Junctional adhesion molecule 3a
- CD226 molecule.
- Junctional adhesion molecule 3B
- Junctional adhesion molecule A
- Talin 2b.
- Talin-2a
Sequence:
MHQSVCLKSLLLLLVGTQVYTQEQCLKASVNTCGDCIKSGPGCAWCKELNFTKTGEQEAARCDTVKLLLDRGCSKENIINPQNIFQNVVNKALVAGKDPVQIQPQEIQLNLRPGMPQTFQLRFKRAEGYPVDLYYLMDLSYSMKDDLANVKNLGNDILEKLNRITGNARIGFGSFVDKTLLPYTDTNEAKLKHPCSDKNEPCQPAFGFQHVLPLTANGNDFKELVKQQHISGNLDPPEGSLDAIMQAAVCLKEIGWGNSTRLLVLATDDGFHMAGDGKLAAILEPNKETCQLDKNKYSKSNIWDYPSVGQVARKLEEQNIQPIFAVTKKMETVYTELSKLIPKSAVGVLSEDSNNVVNLIVEAYNNLTSEVIMAHDALPNFISVKYSSKCTGGKTFSDNGKCDNVNIGLEVIFDVTVTVDRCINDQSFSIGPLGFNEKLKVNVQTLCECNCGDPPGVHPHCKGQGKVVCGSCKCNDGFIGQLCECTIGKKDEASFKAQCRKDNGTECEGKGDCVCGRCQCHLTEGNGHFYGEHCECDDEHCEKFDNKQCAGHGKCKCGKCECDDGYEGTACHCAKSDNECKIDSHVCYNRGKCVCNQCECERGYKGPYCKTCPTCQRPCQQSGSCVECFAFQSGPFEKNCSLACKHLTIKIVDKLVKSDCRVKDKEGCWMAFTMTEELGFDLYSVSVLKDRECPEGPNIIAIVGGSLAGVALIGLLMLLIIKGVLYASDLREWRRFEKDRKHEKTSGTNPLFQNATTTVQNPTFSGDS
Protein: Charged multivesicular body protein 4 (Vacuolar protein-sorting-associated protein 32) (Dd-Vps32) (Q86H98)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins.
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000269|PubMed:15708561}. Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Membrane-associated. Colocalizes to large vesicle-like structures with PDCD6IP/Alix.
Interaction partners:
- Charged multivesicular body protein 3
- ALG-2 interacting protein X
- Charged multivesicular body protein 6
- Charged multivesicular body protein 1
- ESCRT-I complex subunit tsg101
- Charged multivesicular body protein 2a homolog 2
- Vacuolar protein-sorting-associated protein 36
- Vacuolar protein-sorting-associated protein 25
- Charged multivesicular body protein 7
- Charged multivesicular body protein 5
Sequence:
MKLFGKPKPKQDTQETIGKLRLTLDMLEKRQTFLQDKLEKEQEKAKVLVSQKRKREALLCLKKRNNFQNEVTKLQGSYDTLNQQIFALENAKMNMEIMNSMRDGARSLRELHGHLTIDKVDDVIEEIQEQMEIHEEISNAISQPLGNQVEDEEELLRELAEYEQEELDAQLLNIKAPSRELPQEIQVNFPTISKTVPKLSKEEEEIRALEESLAM
Protein: Protein PIN-LIKES 2 (Auxin efflux carrier-like protein 2) (Q9C999)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:22504182}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Auxin efflux carrier component 5
- Auxin efflux carrier component 6
- Auxin efflux carrier component 3
- Auxin efflux carrier component 8
- ABC transporter B family member 19
- Protein WALLS ARE THIN 1
- ABC transporter B family member 1
Sequence:
MSGFSSGNVNSRVVDILSGVVPLLKLICLTVIGLLLAHPKTQLVPRATFRLLSKLVFALFLPCLIFTELGESITLDNIVQWWFIPVNVLLSAVVGSLIGYLVVLICRPPPEFNRFTIVMTAFGNTGNLLLAIVSSVCHTKTNPFGPNCNSRGVSYVSFAQWVAVILVYTVVYHMMEPPLEYYEVVEEEGVEIEEINVENHDASRPLLVEAEWPGIEDKETEHCKTPFIARVFNSISSFSQTSFPEVDLGGEYGGESSSPRSIQCLAEPRVMRRIRVVAEQTPVKHILQPPTIASLLAIIIGSVPQLKSVVFGYDAPLSFITDSLNIMGSAMVPSVMLVLGGMLSEGPNESTLGLRTTIGISVARLLVLPLVGIGIVMSADKLGLISSADPMFKFVLLLQYSTPSAILLGAIASLRGYAVREASALLFWQHIFALLSLTFYIVIFFKLTVETTVQGMQ
Protein: Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737 homolog) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Q13099)
Organism: Homo sapiens (Human)
Function: Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium {ECO:0000269|PubMed:17604723, ECO:0000269|PubMed:28428259}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:17604723, ECO:0000269|PubMed:27767179, ECO:0000269|PubMed:28428259, ECO:0000269|PubMed:28625565, ECO:0000269|PubMed:36606424}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:27767179}. Cytoplasm {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q61371}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q61371}. Note=Colocalizes with ENTR1 and gamma-tubulin at the basal body of primary cilia (PubMed:27767179). Colocalizes with ENTR1 and pericentrin at the centrosome (PubMed:27767179). In sperm cells, localizes to the manchette, head-tail coupling apparatus and flagellum (By similarity). {ECO:0000250|UniProtKB:Q61371, ECO:0000269|PubMed:27767179}.
Interaction partners:
- Intraflagellar transport protein 80 homolog
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport protein 57 homolog
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 27 homolog
- Intraflagellar transport protein 74 homolog
- Intraflagellar transport protein 172 homolog
- Clusterin-associated protein 1
- Intraflagellar transport protein 70B
- Intraflagellar transport protein 52 homolog
Sequence:
MMQNVHLAPETDEDDLYSGYNDYNPIYDIEELENDAAFQQAVRTSHGRRPPITAKISSTAVTRPIATGYGSKTSLASSIGRPMTGAIQDGVTRPMTAVRAAGFTKAALRGSAFDPLSQSRGPASPLEAKKKDSPEEKIKQLEKEVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTTPENINLDLTYSVLFNLASQYSVNEMYAEALNTYQVIVKNKMFSNAGILKMNMGNIYLKQRNYSKAIKFYRMALDQVPSVNKQMRIKIMQNIGVTFIQAGQYSDAINSYEHIMSMAPNLKAGYNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYISPSDDPHTNLVTEAIKNDHLRQMERERKAMAEKYIMTSAKLIAPVIETSFAAGYDWCVEVVKASQYVELANDLEINKAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSALYYMGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDTHRKFPENVECLRFLVRLCTDLGLKDAQEYARKLKRLEKMKEIREQRIKSGRDGSGGSRGKREGSASGDSGQNYSASSKGERLSARLRALPGTNEPYESSSNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE
Protein: CD209-like protein (Q64HY2)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MEEVENYTSLHEFTEDISSRGNKPILNNHNAQELKRGSECLRGQTALFVLIGLLASICANIALSVLLFSRPLPSVPLEAASLTLKLNSVRGRYVRLCDDYSKLGQSCSKTVRKCRECPEGWIHVDEKCYSFSNDKMDWPSSRDSCTSLGSHLTILHSKKQHDALEKEARRIGGFDYHFWIGLSDREKEGDWRWVDNTTLTKKYWNEYSSEPDNHQSGGSHGEDCATLDSHSQTWFDVPCDHIYKRICQMDAIRLD
Protein: Uncharacterized protein (G8BIX0)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Interaction partners:
Sequence:
MRQFTLINFIALLIASTTSFAIVAPFFGQAAAFNSLQEKIYQPADMAGENIAKTFIGGEPPASRTRWQEPKSTSAVISSSSGNDTATVLSTRSDSGGGKVVVPTWLSEIYHIADTFFAYI
Protein: Lysosomal cobalamin transport escort protein LMBD1 (LMBR1 domain-containing protein 1) (A0A3B3IT31)
Organism: Homo sapiens (Human)
Subcellular location: Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004155}.
Interaction partners:
Sequence:
MATSGAASAELVIGWCIFGLLLLAILAFCWIYVRKYQSRRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANANVSRQIEDTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTSKCTQIKTALKYTLGFVVICALLLLVGSLVCKPELSGAGISKLFLKHRYAFVPLNVPNNKNSTEWEKVKSLFEELGSSHGLAALSFSISSLTLIGMLAAITYTAYGMSALPLNLIKGTRSAAYERLENTEDIEEVEQHIQTIKSKSKDGRPLPARDKRALKQFEERLRTLKKRERHLEFIENSWWTKFCGALRPLKIVWGIFFILVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIETNITSDNHKGNSTLSVPKRCDADAPEDQCTVTRTYLFLHKFWFFSAAYYFGNWAFLGVFLIGLIVSCCKGKKSVIEGVDEDSDISDDEPSVYSA
Protein: Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase) (P19098)
Organism: Gallus gallus (Chicken)
Function: Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
Subcellular location: Membrane; Peripheral membrane protein.
Interaction partners:
- 3Beta_HSD domain-containing protein.
- Hydroxysteroid 17-beta dehydrogenase 3
- Steroid 17-alpha-hydroxylase/17,20 lyase
- Forkhead box protein L2
- 3-oxo-5-alpha-steroid 4-dehydrogenase
- Hydroxysteroid 17-beta dehydrogenase 2
- 3-oxo-5-alpha-steroid 4-dehydrogenase
- Hydroxysteroid 17-beta dehydrogenase 12
- Cytochrome P450 1A4
- Cytochrome P450 1A5
Sequence:
MIPETLNPLNYFTSLVPDLMPVATVPIIILICFLFLIWNHEETSSIPGPGYCMGIGPLISHGRFLWMGVGNACNYYNKTYGEFVRVWISGEETFIISKSSSVFHVMKHWNYVSRFGSKLGLQCIGMYENGIIFNNNPAHWKEIRPFFTKALSGPGLVRMIAICVESTIVHLDKLEEVTTEVGNVNVLNLMRRIMLDTSNKLFLGVPLDESAIVLKIQNYFDAWQALLLKPDIFFKISWLCKKYEEAAKDLKGAMEILIEQKRQKLSTVEKLDEHMDFASQLIFAQNRGDLTAENVNQCVLEMMIAAPDTLSVTLFIMLILIADDPTVEEKMMREIETVMGDREVQSDDMPNLKIVENFIYESMRYQPVVDLIMRKALQDDVIDGYPVKKGTNIILNIGRMHKLEFFPKPNEFSLENFEKNVPSRYFQPFGFGPRGCVGKFIAMVMMKAILVTLLRRCRVQTMKGRGLNNIQKNNDLSMHPIERQPLLEMVFTQEAQTRIRVTKVDQH
Protein: Peroxisomal long-chain fatty acid import protein 1 (Peroxisomal ABC transporter 2) (P34230)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the import of activated long-chain fatty acids from the cytosol to the peroxisomal matrix.
Subcellular location: Peroxisome membrane; Multi-pass membrane protein.
Interaction partners:
- Peroxisomal long-chain fatty acid import protein 2
- Long-chain-fatty-acid--CoA ligase 2
- Peroxisomal hydratase-dehydrogenase-epimerase
- Acyl-coenzyme A oxidase
- Peroxisomal membrane protein import receptor PEX19
- Peroxisomal biogenesis factor 3
- 3,2-trans-enoyl-CoA isomerase
- LSM complex subunit LSM6
- 5'-3' exoribonuclease 1
- Peroxisomal membrane protein PMP27
Sequence:
MISTASAFYQKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKKDSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHKGGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQYANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSVASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTLALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKRELENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSEDTLQLKEPGNDMTADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNKFNDLLDANKGDDEKEPRDERCIVEYDDSRIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNGCGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFREQIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQLSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAVAPEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQFGPFNPKERLCNEEKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLNLFEKIEDPKTSKSNALFNANKGQRITSPTGQETSKRLPLFSQPSSSASSNLLRNNKSLNKKVKTKKEEGKER