Protein: Ciliogenesis and planar polarity effector 1 (Protein C5orf42 homolog) (Protein JBTS17) (Q8CE72)
Organism: Mus musculus (Mouse)
Function: Involved in ciliogenesis. Involved in the establishment of cell polarity required for directional cell migration. Proposed to act in association with the CPLANE (ciliogenesis and planar polarity effectors) complex. Involved in recruitment of peripheral IFT-A proteins to basal bodies.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium {ECO:0000269|PubMed:25877302}. Note=Localizes to the ciliary transition zone. {ECO:0000269|PubMed:25877302}.
Interaction partners:
Sequence:
MEMRLEVLTSTSIKQKKPWPRVSWLGQENEAVFLLDEKFINEINLLSGRTKKKIPSLQPLLKDVVFLATSTNDVWLSGVLTTGELFLWNKDQDCLKKIHVTEKPKEAIKAAVASSSRLYLYVAENGKRILLITSSGCILLWEYLELKNILSSKSLSLVGQWSQIVPEEAVSLPSTKDKEAVVAAVFVKNELLGDCCLCSFTFYSGECLKLTFLDIQWYENIFTSVRSLLFRVHWAQQECPLCSLIPRCASVKSRGALISAFSRDGLALAVTLNQKDPTATQVLFINTLNFVTLCGGLKGCSNKNPVVPATLTRSYWVGDISWTHDSLFLTCVLKRGSLVLLTCLGELLTLVTFGCSIEFGPAEFIPLHPLITYRPQQLPFQDSNNCVDSSASESDPLRQRFSIKAHSRLPYLIISDGYMVTTLRFLDNQSPTMLMRSLLLDSTQRLEKAYQSMMLSEPKDKGLNFRSLDSLRSSLLKHQGKESSVHCTVPRFLQAEETMKLNETTDFQDFEGEETNEVEQFVNNSFSFCNQKKDLPFDIVKEGRLEFASMFDTVHAKDASKETDRNTAELHRIQKTLLAAWTIGISKNVTEKKLMLNYTILCITHFFYILQFIKCPVPKFDLFLNKSLKRNAWVLCVFQLFHQCLSVHYWDMRYRQNMGHLIRLTANTVKLLLTQRQEHGSFSERLLACLSLLRTVTVHLNGTCSLQPEAVPAAADESRPAELDSLMVPIFQASKENWPWDSSLKIYPQVTNLVQKPGHRLIALWRLLYKKTLWYQAQLSQRTPDGDRRLTENIRHEVSVVKTLLCHVQTNLQMAGDSLNQALELTPISGEECFLLASYEKSVCLWKKALQETQEKGGRRTCFLQLRYYLSLLYCHLYCYNLNDAQGLCDHLVRELLSRSQLPVRESQDCSDCEIAVTGNVHPEAALRVVQCMARFMAAYFTNEPLFILPPHSVSVLPPLHVKTEHSLRLIPLQHSKVASVIRDQNLSNVWTVEYTLELLFIGGLIPEAVWMAHKLGDWKTSVSIGVAYQVFCKHDCNFARSKKKGMDLPLNMIPAQIFQEKLQCFLGQPVSLTKKNEKGSKYKQFTDPIEEEDASLLFGSVQEVLKASVMADADIVSETLQLLMDSAKDFSKKLWGLVPVDLYLPAPPLYCPQPAVLSEEHGDNLLLKAEKDNRQKLSGILQRVLLLFRASRCSFPVAQWYILQLRWARKVMQKIRVKGSLPSLGSFPESLLNYCKGGIAFFRPGATGDHTLDEVSIKALGCFRELCALCWMLHVRDKLSYTCRQYQKARENTKIEKDLEVGFDSCVVEHCFHALEWACRMLPFSRFFNMEELIQDIILSLIGELPPIRKVAEIFVKAFPNPEAIRVPLREKYHSLQQKLKHGVVKGPQTEELMSTVMRHVRKVRVKALKRVQRNIGAFEMDIWEPDEEDKPAATPAADRFSLGPSVSSTLTLDLGSSLLHSDADTFSETLSLEEKTWIHLYQRHTPSHMELALVGKKPSDKKKVSNQKENSQRKEDDETPGKEALPVIGVWEFERDDDEYISFLELFLSYILERDLCSSDPGIPFLTSFSGRLREHELNSLLFDVHTTLKRRQSKTISENVYRAGSCFAVTPESQEPENLSSLNSVGARHFESQALSASALGNQSGSTLENPLQSGSTSENPLQSDVMNWERRAGLFGLKQKPMYRVPDDKREKPTVQRSSNHSFWVPESIKPGRHRFRALEGSAGPPREDLPLALQSMFGDAGRLVEWMIRWSDRRLLCDPGVTPSSCKYSPVIRVKTSTAAILTSLWLLEQPYSAAYTAKNGIIKVLERHHTEPQVAAERESDVDADCPAAVAAQEGTECWNRMPAEAENHDVKDTGDEIAPVTPGSERELVHADGRHSEAGSSTQDEMDVHISDSEEGPVESLRGPSAVICRPESQLSSEHSEEEAQCSRKEPRDASVDTNLTEQKGAQISDLKEKSPTVLPLMSNGAQDTSQTPQKTQGNEHRAQLPDASESVRQMLQDEMFKLVQLQQINFLSLMQIVGPSVASLPDMHGLLQQAQSVRFGESQVSNSTKSDCIEVNSRQRVSARAQSMGECTREPGKNSPADHKRISRPDQDSSGDTQDIPHGSVPLCQLDGQPEVRGQTGAPRSFAPASFPPAPAADSGLQLLFTPAAIQKTPQLIPPARAGAPGRGFPLLHFQPKRDFKPLSLPVGRIPQVSFRPQAQPKEAWSLSDSCQPPVSQRTVHTTLPSPSDSSHCNAEAMRKAEAVLTGIPKHVNMGQYAGQGYLTPQQDSSVFIKPENVFDVKPSPPETALQNSFGLPLLHLQFKPPYVFSAPPRAFSRFPSVPGTEGRNQPQLSLLHPCLPPENTYKKPQLIPLENLLAFKRSQQKLAHSVSGQGDAAPHFVGVSMDAAGITQGKQRQSRRAKRELQEGRAQKPRRKPNVSFRPEDSLISNDSEVIIEPKEQLGHHDSQHLDKFDIPFEMLEDDINTSAGLHFMASVRKKAVGSHDASTNTDPDKEGPSQKADSESSKNPQATAASSGHEPLKVPQLLIPDIYLNVRLPSGIAEKPLSPSPPHMAGHKYIDVVDIEADDLLGLPACEEPSDEVTKQQSHPPHAPSSAELHCMAASIVDAAPPHTFQSQESASSTRGLISEPAKVTQSCQSGESWRKSVIEAKEPEIPSVAPPSDRQQDRDILEQNFQFKEQSTKLDSVGQSLLWTLLQNASPACPTPSPAVCPRPSSPACPPPSPAVCPPPSPAACPTPSPAAQKFEHLTAKLQEMDEQLVAVQTMAENIEQDFPASQVLNLHWEKAGLGNHVGLSSGPDIEKLLASKAISISEEVSLQTQEDVEEQKDAEETSETEFSEAENHSSQKTYACPSVGSAACSSVGWNIPSPGLNDSNELLESGSEDQLQVTGLTDIADIIGDLITKSGVSSHELGLTECQARSISRIQRPPDRGPRRTAEERREIKAWMRRKQKERMSEYLGQLAERRGRERNPFCPTSSPFYMTSRQIRQRQKMKREKDRLQLSKHYSQRLSQAYSLMNELLSDSAHITAPAENPLPPGPYRRQRGSSPKRENAHGQSLPVNRPGGDRHISRSSHLCKGQPRGSSQLRGSQPPCQSQKPLRSRGAAGVGPPVQQACREDEREEMVVSPWTLPSEIHRILHGRPESLLQDMSPADEEEPEPPLLAGGMDSVSESTGSILSKLDWKAVEDMVASVEDKNLSVHWALDQ