wanglab/gogpt-training-data huggingface dataset:
Protein: Inner membrane protein YdcO (P76103)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- HTH-type transcriptional regulator SutR
- Uncharacterized protein YhhM
- Uncharacterized protein YjgZ
Sequence:
MRLFSIPPPTLLAGFLAVLIGYASSAAIIWQAAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQGLTLNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQFTLCGSMLLVWLATKAVAPRYAVIAAMIIGIVIVIAQGDVVTTDVVFKPVLPTYITPDFSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALVFSPFGVYSVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLLAGLFGSAITGMMAALPVSWIQMLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLVGIGSAFWGLIAGGVCYVVLNLIADRNRY
Protein: Conserved protein (O05777)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Cell division protein FtsX
- SsrA-binding protein
- Cell division ATP-binding protein FtsE
- Protein-glutamine gamma-glutamyltransferase-like C-terminal domain-containing protein
Sequence:
MTTPGRPLTTLDKSDVLAGLFAVWHSLDALLDGLLETDWQATSPLPGWDVKAVVSHIIGTESFLLGIAAPEPDTDVSALAHVRNPIGVMNECWVRHLGTESGVGLLERFRAVTSQRRKVLASLSDDEWNAPTTTPSGPDSYGRFMRIRIFDCWMHEQDIRAAVQRPSSDDELGGPASPLVLDEIAATMGFVVGKLAKAPDGSRVLLELTGPLSRSIRVSVDGRARVVDDFGGPAPTATIRLDGLQFTRLAGGRPMSPARSQDVELGGDKELAGHILERLNFVI
Protein: UDP-galactose/UDP-glucose transporter 3 (AtUTr3) (Q9M9S6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential sugar transporter required for the transport of UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum. Essential for pollen development and involved in embryo sac progress.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19906043}; Multi-pass membrane protein {ECO:0000269|PubMed:19906043}. Golgi apparatus membrane {ECO:0000269|PubMed:19906043}; Multi-pass membrane protein {ECO:0000269|PubMed:19906043}.
Interaction partners:
- Protein SODIUM POTASSIUM ROOT DEFECTIVE 2
- Calcium ion-binding protein
- Probable sugar phosphate/phosphate translocator At5g25400
- Probable sugar phosphate/phosphate translocator At4g32390
- ADP-ribosylation factor C1
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH10
- Probable serine/threonine-protein kinase PBL23
Sequence:
MESHGSGLRRVLLLSFCVAGIWAAYIYQGILQETLSTKKFGEDGKRFEHLAFLNLAQNVICLVWSYIMIKLWSNGGSGGAPWWTYWSAGITNTIGPAMGIEALKYISYPAQVLAKSSKMIPVMLMGSLVYGIRYTLPEYLCTFLVAGGVSMFALLKTSSKTISKLAHPNAPLGYGLCFLNLAFDGFTNATQDSITARYPKTNAWDIMLGMNLWGTIYNMVYMFGLPHGSGFEAVQFCKQHPEAAWDILMYCLCGAVGQNFIFLTISRFGSLANTTITTTRKFVSIVVSSVLSGNPLSSKQWGCVSMVFGGLSYQIYLKWRKLQRMQKKKKA
Protein: Autophagy protein 5 (APG5-like) (Q9W3R7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in autophagic vesicle formation. Conjugation with Atg12, through a ubiquitin-like conjugating system involving Atg7 as an E1-like activating enzyme and Atg10 as an E2-like conjugating enzyme, is essential for its function. The Atg12-Atg5 conjugate acts as an E3-like enzyme which is required for lipidation of Atg8 and its association to the vesicle membranes (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Preautophagosomal structure membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Ubiquitin-like-conjugating enzyme ATG3
- Autophagy-related 16, isoform F
- Autophagy protein 12-like
- Autophagy-related 1, isoform B
- Ubiquitin-like modifier-activating enzyme ATG7
- Autophagy-related 8a, isoform A
- Autophagy-related 8b, isoform A
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- NAD-dependent histone deacetylase sirtuin-1
- Autophagy-related 18a, isoform E
Sequence:
MAHDREVLRMIWEGQIGICFQADRDEIVGIKPEPFYLMISRLSYLPLVTDKVRKYFSRYISAEHQDGAVWFDFNGTPLRLHYPIGVLYDLLHPEEDSTPWCLTIHFSKFPEDMLVKLNSKELLESHYMSCLKEADVLKHRGLVISAMQKKDHNQLWLGLVNEKFDQFWAVNRRLMEPYGDLESFKNIPLRIYTDDDFTYTQKLISPISVGGQKKSLADLMAELSTPVRRAVGCRTHGIDLHEETQLQWMSEHLSYPDNFLHLSVDYKDV
Protein: Glutamate--tRNA ligase, cytoplasmic (EC 6.1.1.17) (Glutamyl-tRNA synthetase) ((c)ERS) (GluRS) (P85) (P46655)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). In mitochondria, constitutes the nondiscriminating glutamyl-tRNA synthase that generates the mitochondrial mischarged glutamyl-tRNA(Gln) substrate for the tRNA-dependent amidotransferase (AdT), which generates mitochondrial glutaminyl-tRNA(Gln) by transamidation of glutamyl-tRNA(Gln).
Subcellular location: Cytoplasm. Mitochondrion. Note=Largely excluded from the nucleus.
Interaction partners:
- Methionine--tRNA ligase, cytoplasmic
- tRNA-aminoacylation cofactor ARC1
- Putative proline--tRNA ligase YHR020W
- Isoleucine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Methionine--tRNA ligase, mitochondrial
- Asparagine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase, mitochondrial
- Glutamine--tRNA ligase
Sequence:
MPSTLTINGKAPIVAYAELIAARIVNALAPNSIAIKLVDDKKAPAAKLDDATEDVFNKITSKFAAIFDNGDKEQVAKWVNLAQKELVIKNFAKLSQSLETLDSQLNLRTFILGGLKYSAADVACWGALRSNGMCGSIIKNKVDVNVSRWYTLLEMDPIFGEAHDFLSKSLLELKKSANVGKKKETHKANFEIDLPDAKMGEVVTRFPPEPSGYLHIGHAKAALLNQYFAQAYKGKLIIRFDDTNPSKEKEEFQDSILEDLDLLGIKGDRITYSSDYFQEMYDYCVQMIKDGKAYCDDTPTEKMREERMDGVASARRDRSVEENLRIFTEEMKNGTEEGLKNCVRAKIDYKALNKTLRDPVIYRCNLTPHHRTGSTWKIYPTYDFCVPIVDAIEGVTHALRTIEYRDRNAQYDWMLQALRLRKVHIWDFARINFVRTLLSKRKLQWMVDKDLVGNWDDPRFPTVRGVRRRGMTVEGLRNFVLSQGPSRNVINLEWNLIWAFNKKVIDPIAPRHTAIVNPVKIHLEGSEAPQEPKIEMKPKHKKNPAVGEKKVIYYKDIVVDKDDADVINVDEEVTLMDWGNVIITKKNDDGSMVAKLNLEGDFKKTKHKLTWLADTKDVVPVDLVDFDHLITKDRLEEDESFEDFLTPQTEFHTDAIADLNVKDMKIGDIIQFERKGYYRLDALPKDGKPYVFFTIPDGKSVNKYGAKK
Protein: D-proline dehydrogenase (D-Pro DH) (D-Pro dehydrogenase) (EC 1.5.99.13) (A1RVM8)
Organism: Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)
Function: Catalyzes the dehydrogenation of D-proline. Can also use other D-amino acids, but with lower efficiency.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11823469}; Peripheral membrane protein {ECO:0000269|PubMed:11823469}.
Interaction partners:
- FAD-dependent pyridine nucleotide-disulfide oxidoreductase
- FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Sequence:
MKVAIVGGGIIGLFTAYHLRQQGADVVIIEQGEPGGWSKAAAGILEFTRFVINRINVRSYPKRYLSMALRGDARIKTWDWRWISAYLRAWGREPTQDMWEAIKTLGEYSWRQYRALAEAENDFAYSEEPLYEVGIDVAAALEEAKRDPLSPKVETGRCCGREALVYLDAAKLSTEDFVARMLRELQGVQMVRRRAQEVAGREVWLEGGDVVKADAVVVAAGYWARKFGIPVAPFKGYGFRTTAKAQSMFIEMTKGVAVVPLPKWTKVTGRFDLDGTEDHSPSARVLQRAREVLGNFEVLDMSVGYRPCTPDGFPIVDKVGEVVIVTGACRLGWTYGPALGKLAADLALGKPGVEALTARRFRR
Protein: Exocrine gland secreted peptide 6 (Exocrine gland-secreting peptide 6) (A8R0U0)
Organism: Mus musculus (Mouse)
Interaction partners:
- Lacrein
Sequence:
MTSLPMMIFLVILLLPSMPTEGRVLTQTQEQSTISADQKTNQETFLDKIESKGNPGNPSIKEAIEMFSCAFDQDKTLLEDQSNSDQPSLNLSKLMTTLNKCGAQKYKVAEYVPEDGLAGHEWPEGSLVLRLLDNPV
Protein: HECT-type ubiquitin ligase-interacting protein creD (Carbon catabolite repressor D) (Q6SIF1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability.
Interaction partners:
- Catabolite repression protein creC
- E3 ubiquitin-protein ligase RSP5
- Ubiquitin carboxyl-terminal hydrolase creB
- DNA-binding protein creA
- Adenylate cyclase
Sequence:
MALSFFSGGGSASHAKYFDIRLDEDYIVFRGGEQEAASAHLSGKLVLCVSEPISIKHIRLHLTGISRVCWHLPSSSAGGGRKNWRERVFYEKTWKFRDAGKSKTEILPAGNYEYPFDVILEGSMPESVEGLSDTYVTYRFKAEIGRKYAKDIVVRRPLRIIRTLESSALELSHAMSVENIWPNKIEYSISTPTKAVIFGTSIRVDFKLIPLLKGLGIGQIISQLIETHDLTLNPEDPDAIRNTYKTTRTIINDEHTIDEENSLEIIDEAAEGFQFSRTLDLPKTLTRCLQDTDTRGIKVRHKLKFRVQLLNPDGHISELRATLPVSIFISPNLAIDDNNNLVDSSPQTTQRALDDLAQQAPPLYGEHQFDQLYSEVDPSGYRTPGPGSGPGTPFGTLSRNLSAENLASMNAITHTDISASALHHRLVNLDLRGHGRVSASEHDHLGVPSDNGPPSGSNTHGSNTHAPGSPELSRRASDEDVHDNIPSGMATPFIPHSAELETLSRVPSYSTAVRSSVRPHDSDLPDYQAVVAETVHMSAPQSPQQAHIRGSGTGRGSDSYFSAPMDFFHRPAFLHSRSHSHSDDERRIRLTQARGRA
Protein: Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3) (Q60936)
Organism: Mus musculus (Mouse)
Function: Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity). Shows an unusual selectivity for binding ADP over ATP (By similarity).
Subcellular location: Mitochondrion membrane {ECO:0000250|UniProtKB:Q8NI60}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Ubiquinone biosynthesis protein COQ9
- 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
- Ubiquinone biosynthesis O-methyltransferase, mitochondrial
- Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial
- All trans-polyprenyl-diphosphate synthase PDSS1
- 4-hydroxybenzoate polyprenyltransferase, mitochondrial
- All trans-polyprenyl-diphosphate synthase PDSS2
- NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial
- Protein BEAN1
Sequence:
MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELLLAARALQSTAVEQFSMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGTSLDFSAASSLDQSLSPSHSQGPAPAYASSGPFREAGLPGQATSPMGRVNGRLFVDHRDLFLANGIQRRSFHQDQSSVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNSDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELISGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRMKSGLQ
Protein: Tubulin alpha 8 (V9GZ17)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
XFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHCQRIQLGISCSSMTSLVSASLEPFLKAVFDFHESFEDGRPADLQNAPRFGLARTRVLAKGFRLLTFDGNSTEVIPRWLHSVLWWHAIPVFPALMTFLYRIFTLITFFIVIM
Protein: EamA domain-containing protein (O02057)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- alpha-1,2-Mannosidase
- Nose resistant-to-fluoxetine protein N-terminal domain-containing protein
- Mitochondrial coenzyme A transporter SLC25A42
- Stomatin-like protein stl-1
Sequence:
MSATNRESTGCLDSKTVGICLLLIVNVLWVLSSELTRFIFVDEEFRRPFFTVYVKSCTLIIYMIRYLFFEAKDDHNSYKILITENSIDSENYEISCESLALEGYESVTDVDSDVESVIVDGEKRQRKIRFAERREIRRMPASNAEDQRKARLPYRHPTIECQLYLSRHVKYTLFFFAPLWLLCSFTYQAALAFTSVSSLNLVSSSSSVFVLAFAICFPSTNNRFSAYKCLLVAINIAGVLIVSHYIPSFLGALFAQMSALAYAVYLFAFGHFEEKYGKLDINLMFGAIGVIALVLGTPTLNLLDRFGVEPLHPLPNATQFSSILFSALIGTIVADYLWLLAAGMCDSLTTCLSMTVSIPLSFLADTVIRSKAPTLAQVIASIPILVAFVGAAYAQNPSTSIRKGLSKRVRKVESLSPDNEHLMDSLSDE
Protein: Alpha-amylase SusG (EC 3.2.1.1) (Starch-utilization system protein G) (Q8A1G3)
Organism: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
Function: Alpha-amylase that cleaves starch into oligosaccharides before internalization for degradation, the first step in starch degradation.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:10572122}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000269|PubMed:10572122}.
Interaction partners:
- Glucan 1,4-alpha-glucosidase SusB
- Pullulanase
- 1,4-alpha-glucan branching enzyme
- Alpha-glucan phosphorylase
- Alpha-glucan phosphorylase
- Alpha-amylase
- 4-alpha-glucanotransferase
- Alpha-amylase
- Alpha-glucosidase
- Outer membrane protein SusE
Sequence:
MNKHLHFLSLLWLSMLMAFMTACSDDKNITDPAPEPEPPVEGQWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHDEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSDSYTLKLGGYASVVFKLGN
Protein: Fused nickel transport protein NikMN (Energy-coupling factor transporter probable substrate-capture protein NikMN) (ECF transporter S component NikMN) (D5AQY8)
Organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Function: Part of the energy-coupling factor (ECF) transporter complex NikMNQO involved in nickel import. The complex confers nickel uptake upon expression in E.coli; can also transport cobalt with a very low affinity.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Nickel transport protein NikQ
- Nickel import ATP-binding protein NikO
- Cobalt transport protein CbiQ
- Cobalt transport protein CbiN
- Cobalt import ATP-binding protein CbiO
- Cobalt transport protein CbiM
- DUF4198 domain-containing protein
- Energy-coupling factor transporter transmembrane protein BioN
Sequence:
MHIPDGYLSPVTCAVTFAATVPFWYVSMRKLDRDLNGQHLPLVALVAAFSFVIMMFNLPIPGGTTAHAAGIGIAAVLLGPWAAVPAISVALLIQAIFFGDGGITAFGANCLNMAVVGPMVAAAVYALGTRGAAIGSRRRVIMAGLASYAGLNAAALLAAVEFGVQPLFFHDAAGAPLYAPYPLSVAVPAMALTHLTIAGAAEFIVTAGLVAWLQRSNPELLAPRRAPAAPERHLRLWAGIGALVVLCPLGLIAAGTAWGEWGAEDFTSEAGRAAMAGASGGVAPPAGLPGGFARLAELWSAPLPDYAPAFVQNAPLGYVLSALLGVALIVAGIGLSAGLRALTRRAG
Protein: Intestinal acid phosphatase (EC 3.1.3.2) (Q19076)
Organism: Caenorhabditis elegans
Function: Acid phosphatase required for normal growth and development. Specifically required for normal gut differentiation.
Subcellular location: Membrane {ECO:0000305|PubMed:1652526}; Single-pass membrane protein {ECO:0000255}. Membrane {ECO:0000305|PubMed:15733671}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:15733671}.
Interaction partners:
- Probable FAD synthase
- ACid Phosphatase family
Sequence:
MVSAISIVAIFALEGFVTTYSDGTKDLVFVQTLWRHGDRSPTKTFKTDPFQEDAWQFGGGGWGQLSPAGMKQHLNLGKMLRNRYVTNYNFLPNKYNAKQIYVRSTDVNRTIISAMSNLLGQYGQNDNSSTPGLDYPDVDGWPAGYVPIAVHTVDDDTDHLGNMESTCPFKDQVWELAKTSDEVKSFVNSADVQAVLGNLTNYCGQPVDIDNLWIITNALYIEQIYYNATLRTKNNWFTDAFYAKADAINDQVQLFQNGIFKTVPNIVNGHDVGVLTRKVRGGPILNDMVMHINLKLMCQGQTTPNCTWINNLKNYIYSAHDTTIYAFFSALLIEEYAVKPSGGYPLYSAAVLLELYIDSVDKKPYFKMVYHEQDGSGFKDVTMGIQGCPQNSSYCDLDILRNFANTIKPDQPIDQWCLTDLNKSSSFATVSMLFIAAILAINNNFLGLF
Protein: Heat shock protein beta-2 (HspB2) (Q99PR8)
Organism: Mus musculus (Mouse)
Function: May regulate the kinase DMPK.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Localizes to nuclear foci. {ECO:0000250}.
Interaction partners:
- Cytochrome c, somatic
- Cytochrome c, testis-specific
- Mitogen-activated protein kinase 14
- Heat shock 70 kDa protein 1B
- Mitogen-activated protein kinase 11
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 13
- RAC-alpha serine/threonine-protein kinase
- Plectin
- Heat shock protein beta-3
Sequence:
MSGRTVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAARAGEGARAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEIARVEP
Protein: Bridging integrator 2 (S4R418)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAEGKAGGAAGLFAKQVQKKFSRAQEKAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQTSFKSPWYQKTTTSQHLNLKKRYPQVKIHNSEEKLPRLLLPQTSPEKLFNQRV
Protein: Synaptotagmin-12 (Synaptotagmin XII) (SytXII) (Synaptotagmin-related gene 1 protein) (Srg1) (P97610)
Organism: Rattus norvegicus (Rat)
Function: Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release. Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids. Essential for mossy-fiber long-term potentiation in the hippocampus (By similarity).
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:17190793}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAVDVTEYHLSVIKSPPGWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYRYLQQKYGEAYVEAKLKRVPPWNAQRTTTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMDYDGASHTLHVAVLQGKDLLEREEATFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSVPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPGASGMGTTHWNQMLATLRRPVSMWHPVRRN
Protein: Ribosomal protein S5/Elongation factor G/III/V family protein (F4JB05)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Probable elongation factor 1-gamma 2
- Large ribosomal subunit protein uL18y
- Small ribosomal subunit protein uS2y
- Small ribosomal subunit protein uS2z
- Diphthine--ammonia ligase
- Large ribosomal subunit protein uL4z
- Large ribosomal subunit protein uL4y
- Large ribosomal subunit protein eL8z
- Large ribosomal subunit protein eL8y
- Small ribosomal subunit protein uS14z/uS14y/uS14x
Sequence:
MSVIAHVDHGKSTLTDSLVAAAGIIAQETAGDVRMTDTRADEAERGITIKSTGISLYYEMTDASLKSFTGARDGNEYLINLIDSPGHVDFSSEVTAALRITDGALVVVDCIEGVCVQTETVLRQSLGERIRPVLTVNKMDRCFLELKVDGEEAYQNFQRVIENANVIMATHEDPLLGDVQVYPEKGTVAFSAGLHGWAFTLTNFAKMYASKFGVSESKMMERLWGENFFDSATRKWTTKTGSPTCKRGFVQFCYEPIKIMINTCMNDQKDKLWPMLEKLGIQMKPDEKELMGKPLMKRVMQAWLPASTALLEMMIFHLPSPYTAQRYRVENLYEGPLDDKYAAAIRNCDPDGPLMLYVSKMIPASDKGRFFAFGRVFSGTVSTGMKVRIMGPNYVPGEKKDLYVKSVQRTVIWMGKKQETVEDVPCGNTVAMVGLDQFITKNGTLTNEKEVDAHPLRAMKFSVSPVVRVAVKCKLASDLPKLVEGLKRLAKSDPMVLCTMEESGEHIVAGAGELHIEICVKDLQDFMGGADIIVSDPVVSLRETVFERSCRTVMSKSPNKHNRLYMEARPMEDGLAEAIDEGRIGPSDDPKIRSKILAEEFGWDKDLAKKIWAFGPDTTGPNMVVDMCKGVQYLNEIKDSVVAGFQWASKEGPLAEENMRGVCYEVCDVVLHADAIHRGCGQMISTARRAIYASQLTAKPRLLEPVYMVEIQAPEGALGGIYSVLNQKRGHVFEEMQRPGTPLYNIKAYLPVVESFGFSGQLRAATSGQAFPQCVFDHWDMMSSDPLETGSQAATLVADIRKRKGLKLQMTPLSDYEDKL
Protein: Guanine nucleotide exchange factor (Q91ZZ2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSSGLGLRRSPEMSGKIEKADSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSKIPEKPVSKEARDRFLPEGYPIPLDLEQQAVEFMSTSAVASRSQRQKNLCWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQTDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGQPELPLTDREMEILNKTTSVSPSAELLPDSTSEEVAPPKPPLPGIRVVDNSPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVECYTQRRLSGGSRSCGGESPRLSPCSSTGKLSRSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPPQAACNLSPLPESLGESGPPFLGHPFQLPLGSCLQQEGQQTDTPPALPEKKRRSAVSQTTDSSGCRVSYERHPSQYDNISEGDLQNPVPVQPVPYPPFAAVLPFQQGASSASAEFVGDFSVPELAGDTEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQSEHIYQQKNKMLMEVYGFSESFCGSDSTQELAPPPALPPKQRQLEPPSGKDGHPRDPSVSSASGKDSRENGERSPKSLDGLESAQSEEEVDELSLIDHNEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILKLLMELVFRLVCSGELSLARVLRKNILDKVDQKKLLRCAHSDQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQRQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQAHYEIRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
Protein: Pyruvate dehydrogenase E1 component subunit beta (EC 1.2.4.1) (Q8IL09)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- 2-oxoisovalerate dehydrogenase subunit alpha
- Pyruvate dehydrogenase E1 component subunit alpha
- Dihydrolipoyl dehydrogenase, apicoplast
- Dihydrolipoyl dehydrogenase
- Pyruvate kinase
- pyruvate kinase
- Glucose-6-phosphate isomerase
- dihydrolipoyllysine-residue succinyltransferase
- Fructose-bisphosphate aldolase
Sequence:
MGRKRNNIVNIRYNFFLIYFWVIFMYPCETNKGNVKPLNFIKGKNIFLNITKNKVKHLNTINGIETISNVENKNILNDTNYINEMKNIKVRRNISEALHMAIYEEMKKDKGVYVLGEDVGLYGGSYKVTKNLAHFFGFSRVLDTPICENAFMGLGIGSAINDLRPIIEGMNLSFLILAFNQISNNACMMRYMCDGQFNIPIVIRGPGGIGKQLGPEHSQRIESYLMSIPGIKIVSCSTPFNARGLLKSAIRDNNPILFIEHVLLYNYEQEIPLLPYTLPIDKAEVVKNGKDLTVLSYGITRHLASEAAKELTKFNIDIEVIDLISLKPFDMETIEKSLKKTKKCLILDESAGFGGIGAELYTQVIEMFSSYLITKPIRLCTKDIPIAYSNKYEDACIIKKEDIVYMSTYLHSLSS
Protein: dihydrofolate reductase (EC 1.5.1.3) (Q54LA0)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Flavin-dependent thymidylate synthase
- Putative folylpolyglutamate synthase
- Serine hydroxymethyltransferase 1
- Serine hydroxymethyltransferase 2
- Aminomethyltransferase, mitochondrial
- formate--tetrahydrofolate ligase
- methionyl-tRNA formyltransferase
- Bifunctional purine biosynthesis protein purH
- Dihydropteridine reductase
- Methionine synthase
Sequence:
MKVSIIVAVSKNNVIGTKAGDIPWELPKDLKHFRDTTHGFPCIIGRISLEAFGDLLPNRFNIIVSSKKEFINIREKIAINLPEYETGITEKGAQYVIVKSVKEAVDYAKDILKTDLVYICGGKGIYEDSQQYSHELIITDVDVHIEENDVVIYNPFPSNDERNKWKVVNQIHHPKDHQNNLDFSITYYVKNEEILIDYKVENQN
Protein: Nanos-like protein (A5Y5A4)
Organism: Schmidtea mediterranea (Freshwater planarian flatworm)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MLNHPESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACIIPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA