wanglab/gogpt-training-data huggingface dataset:
Protein: Sodium/hydrogen exchanger (Q9VIF9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSIRTEQDYDSATPALAQQMNLARRACWRIKSYSSESLFKTYASVITDTSANEIDAEAPPPPRDKTKTRIEPQIAPAKRNSSCTSSDWRGMFSKRTLLICALALILGSAQARPNTSAVGVAPRKVSQDIVDAVTQLNLGQSAPIDAVDVGLDPTPSARVPRPEPLKSGDENAKGDEGHKMERYPLSSVDFARVKTPFIIGIWILSASIAKIGFHMTPKLHLIFPESCLLIVVGVVIGVVLYFCTDVAVSPLTPNTFFFYMLPPIILDAGYFMPNRLFFDNLGTILLMAVVGTIFNIATIGGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAVFEEIHVNEILYIVVFGESLLNDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVVALGGTAIGIIWGFLTGLVTRFTDHVRVIEPIFIFVMAYLAYLNAEIFHMSGILAITFCGITMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATVNNMHVWNTWFVVLTIAFCSVFRVIGVILLSALANRFRLHKLSRVDQFVMSYGGLRGAVAFALVLLVDENVVKQKNMFVTTTIAVIYFTVFLQGITIKPLVKILNVKRANKRKPTMNERIHERFMDHLMAGIEDIVGKTGNYNVRDKFKRFDNRFIRPLLIRDLKGAEPKIIETYSKLTMRDAMEVMRRNPSTIGQMTGTESMSALFRNYTNNYIGGSPSLTNLDNTCSRNLDMAELDYNPSKKDLTDARIHHLLAEELKPYRRHRRLSYSRHAVDDRDLSTQVNYKMQMNFRRMFNDRKHHKRSKRGASNKEAKENVKQNHVSFHDFQQNGTTKQLTNAEECQQNPNEINVVGPSDDWDDGLTFTAKSSPDSDRANNNSLIAHIQNLPGFDASKARIVVQHYAPKADDNPDTDIESPEQAIGPTAAELILPWRRDRSYQSIVAEHPIPEEDRNLSRESDGERRVATPTATESQLPWKRQGDECTDAVQQNEFPAWASNKEYLAYNSPSATFLGGINKPKQPKSVIGLFRRESSSSKAGSVGVGSTGAMDSAASGSETMVVSMSSQPPNAPSTSIHNPRLDKRSQSISSSSLGAGAHQLGPEGHSGPFPVTASHRRNVRRGSMLELSGDTIPEESSYQHGHSKSLCEPADSDEWEGAPLSAAGGANSELLMRMSGREPLLPRPSNTPRAQIRRMNAGAVGGAGVSQAGRKNQVTKALLDYEDSETDSDENDDDEDEDFDSYDDENIVVTTFTTPATGRRPGSSPGSGSEANTATTTTTSIRLTRNNDESII
Protein: beta-N-acetylhexosaminidase (EC 3.2.1.52) (Q0E8H9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Alpha-galactosidase
- Alpha-galactosidase
- Hexosaminidase D
- Glycoprotein 3-alpha-L-fucosyltransferase A
- Beta galactosidase, isoform A
- Probable beta-hexosaminidase fdl
- beta-N-acetylhexosaminidase
- Beta-galactosidase
- N-acetyl-D-glucosamine kinase
- SD21168p
Sequence:
MKSTRTALGVALLLALVSQLAAHSSDDLVYGYECRSGYCQKVELSEENYVKAISLPVCRLFCGSSIGTLWPKPTGTVRLDTLMRQVDISFIDFNFNGIARQQKLWRAVEDRFMNMLEAQIPDRKVLARGGYRMSVNINTPDEPTPARLTLDTDESYTLDIDTDASGHVLANITASNFFGARHGLETLAQLIVYDDIRREVQVTANATINDAPVYKWRGLLLDTSRNYYSVKSIKRTLEGMALVKLNTFHWHITDSHSFPLEVKKRPELHKLGAYSQRQVYTRRDVAEVVEYGRVRGIRVMPEFDAPAHVGEGWQHKNMTACFNAQPWKSFCVEPPCGQLDPTVNEMYDVLEDIYGTMFDQFNPDIFHMGGDEVSTSCWNSSQPIQQWMKKQGWGLETADFMRLWGHFQTEALGRVDKVANGTHTPIILWTSGLTEEPFIDEYLNPERYIIQIWTTGVDPKVKKILERGYKIIVSNYDALYLDCGGAGWVTDGNNWCSPYIGWQKVYDNSLKSIAGDYEHHVLGAEGAIWSEQIDEHTLDNRFWPRASALAERLWSNPAEGWRQAESRLLLHRQRLVDNGLGAEAMQPQWCLQNEHECPIDACSRGSGRLGLIVLLLLTTLSA
Protein: Dolichyl-phosphate-mannose--protein mannosyltransferase 2 (Protein mannosyltransferase 2) (EC 2.4.1.109) (Q5ADM9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Protein mannosyltransferase (PMT) involved in hyphal growth and drug sensitivity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins. Essential protein that plays an important role in virulence.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P31382}; Multi-pass membrane protein {ECO:0000255}. Note=Associates with lipid rafts in a RTA2-dependent manner. {ECO:0000269|PubMed:16534748, ECO:0000269|PubMed:22662216}.
Interaction partners:
- Dolichyl-phosphate-mannose--protein mannosyltransferase 5
Sequence:
MSTSVEPNETEALLRKQNDLSTTASIEEKYPHQQGEAAEDDDDTLKRTQYDEAKETAESLKQVESILAPIVFTALSFFVRFYRISVNDHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEKYPDYIDYTKMRLFNATFSALCVPLAYFTGKEVGFSMFTTWLFTLMVALESSYVTLGKFILLDSMLLFFTVATVFCFSRFNNFNNKSQEFSRKWWKWILLTGVSIGCTCSVKMVGLFVTTLVGIYTVVDLWNKLSDKSISWTKYIQHWFARIVALILVPIFIFMLSFKVHFDLLYKSGTGDANMSSLFQANLAGSDVGGGPREVSMFHSVITLKNQGLSGGLLHSHVQTFPEGSKQQQVTTYGHKDSNNNWIFQRARGQPYYDTSGNTTDIEYIFDGMHVRLMHPQTGRNLHTHDIPAPVSKSEYEVACYGNLTIGDPKDNWTVEIMEQASDEDKMRLHPLTSSFRLKNEVMNCYLGVTGTTLPQWGFRQGEVVCYKNPFKKDKRTWWNIENNRNAVLPPAPEDFKLPKTKFIRDFIQLNLAMMATNNALVPDTEKQDDLASSFWQWPTLNVGIRMCGWGPENPKYYMIGSPATTWTSTVGVILFAFIVLYYLIRWQRQYVDFPSTNPHKLKLFLMGGIYPMFGWGLHFLPFAIMGRVTYVHHYVPALYFAMLVFCYEVESFSSRLNKPNASPVSKLLYLAIYIGLLSLVAGTFWYFRYLSWGMEGPKEDWKHLKLLESWRVSDDQYT
Protein: Uncharacterized protein CG43427 (Q0KIC3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEATDQEVMLEGREDLMSTSATSSTNGGDTNGCGKKLSVTSPDPTPYVTKQRVTRPTPPAPSKNPMQFVQIKPCNLYQTAQEQLKKAEEVKKLKEVKKEEPEEWQNNLDNWKSSRRKRVEHIIDRAVETKKLELEEHDRLRRKSKTFTEMMEERAERGGPRGRAKLASLAVYNEDETNDLSDLGIGTSSASGKSSLSGDYDNNSVMSDHAAELDKAIGAASSVAAGVTAQNVDEQLNHINRNGSNGNHGNGAAVGQTGPSNSSKSAGRQYISSPGYDTSSSNAQASSPDLCEYTYEGAIQDYKQRVQRASSNGNGNANGKLIGEHIAYPTRRGSKIEDRLSGFEVTSPSDTQEGVEKQKVDVPKVDISKRKEIFEQAKAEVSNGGAPAAPKLVFRDGLTNGNSATTAPKSEVRRLSGDISSIRDRMQSLEQQRKAFSSSKSVDVPVPPLKQRLNSLQQSVAKEEQKKPPLVALIDARQLEIMRGEEERMRQQQQKEKHSPSQTTLCAPKPAPPALIIEEPPVADTNDDSGIQEDTADELQQQQQLNAAIAALALEERQLEEAANAVNQIEAEFDELTDLHPSPLPPSPALPAVQQSLQQPTVAQVPAQAVNQAAAPPLRDMEFSVSCTNNFIEPAKISPCDVNVVAASAVSVSKSGPTPNPTSTPNMVSSSPNCNLRRKPSNEMVHHRNLLKMFKETFQNDDDLKEVCEIVTSPGQFTQIIDFSKRPSNPPIPIPTLLPTSTPIPTQIPRPLGKPPMSPKAVRLASSPKGHINPLSSPTNSGFSPPQFSINGRVEIFNSRQLDKPPTPPAPPKKTVRSEHPLKEAVPSPEVVMCAPPMTIVDPDELPKPNTVKALSNCFSQSDSKSLTSPIMSPKPLPSGRIPQITPPASPKPPKRVQLDEVDRSSGDYAPVVGQTKAIVHTPPSKINARANQTLDPLAPNDSLCLHTSSPSEIPSLKACSPNESSLFKLASSRPTSPSVDVASCQKFLNREAPKDIQLAEEDRKRMDQFAVEEMPCDKIDVTKSPQPNTGFQIVTEDLVKKCDGKNISEAVRDLDVPPSQEDIALCAGLLDCLAPAQEPICDSIDVRNGPVPATGFQDISEEEVKKCEKHNKNYVITNRPSSPIGSVRAAHSKALMDTCEQIIAEERKASSQMMKTSLPESVEKPSTPLPGRKSKIPIPKPCCISASGTDSISRAGYVPTAPSHLSGSAQQPLIARTHVVETEIKVKEISPPSIPKTPEQTQLHASPTKEKKAKNIFDFLRRNFGHQEEPQHHSTLNETLEKKVVLTSTKSGVDVVNADEFVRVDNSKFYLASELEDVPVPPPLPKTPAPVNIEIRKKITTNEILEENTTEQALTQEISDLLDDEIMKLEN
Protein: Uncharacterized protein PB7E8.01 (Q9C0V5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Secreted. Cell surface {ECO:0000305}.
Interaction partners:
- Multifunctional tryptophan biosynthesis protein
Sequence:
MSLLVKAALILKCASMLQGVSAQYFCRDTTFDKRTLESVRFESECIPTVNKRDLDPNAEGVYKRSFDGNMNPSDFQLLPLAPRDGAIVNVDKESFSKRSTTNMFDFNFSCYFGSDGHSNDTLCQQYIDVADSVGEQFSRVLNLNTPIVIDVTVVGACTGESVCSQGQGMVAGSIGGEASPSREIPMACSDGLTRYYPQAVVKQLGLSDPPSYADSDITIALNADANFYFGSGDMGYEAVDLAYVLFHEITHGLGFSTGWGVFGYENLTDPYMNALLPTVSYVIGEMNGETMYAFHDVIENAFDRNIFYSIDPNEGLPTIAEFFHSVGAAFTLKADSIAGVVAQMNDTTTQFHIQANEAYRKAINPGRLVIYPDAGIDTYSPFIYLDSSYVPFSSGSSLSHVALHHYDCEPNFLMRAFYTAGATLESYIECAYGSDQADVAYGPIGPAMRTVFRRMGYSVNNLTGVTNEYSESLAKRSLSEKPKTAPTGKQLALHPLRRETSILDSTNTTSTNATNTTTTTSSSSTASSSASASSSTSATSGAAGDLFSVSKNLMMTLTAGLCLITASLF
Protein: Paired amphipathic helix protein Sin3-like 2 (Q9LFQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00810}.
Interaction partners:
- Histone deacetylase 19
- Zinc finger CCCH domain protein
- Histone deacetylase 6
- Paired amphipathic helix protein Sin3-like 3
- Paired amphipathic helix protein Sin3-like 1
- Histone-binding protein MSI1
- Histone deacetylase complex subunit
- Protein ALWAYS EARLY 2
- Histone deacetylase 9
- Protein EMSY-LIKE 3
Sequence:
MKRIRDDIYATGSQFKRPLGSSRGESYEQSPITGGGSIGEGGINTQKLTTDDALTYLKEVKEMFQDQRDKYDMFLEVMKDFKAQKTDTSGVISRVKELFKGHNNLIFGFNTFLPKGFEITLDDVEAPSKKTVEFEEAISFVNKIKTRFQHNELVYKSFLEILNMYRKDNKDITEVYNEVSTLFEDHSDLLEEFTRFLPDSLAPHTEAQLLRSQAQRYDDRGSGPPLVRRMFMEKDRRRERTVASRGDRDHSVDRSDLNDDKSMVKMHRDQRKRVDKDNRERRSRDLEDGEAEQDNLQHFSEKRKSSRRMEGFEAYSGPASHSEKNNLKSMYNQAFLFCEKVKERLCSQDDYQAFLKCLNMFSNGIIQRKDLQNLVSDVLGKFPDLMDEFNQFFERCESIDGFQHLAGVMSKKSLGSEENLSRSVKGEEKDREHKRDVEAAKEKERSKDKYMGKSIQELDLSDCERCTPSYRLLPPDYPIPSVRHRQKSGAAVLNDHWVSVTSGSEDYSFKHMRRNQYEESLFRCEDDRFELDMLLESVGSAAKSAEELLNIIIDKKISFEGSFRIEDHFTALNLRCIERLYGDHGLDVTDLIRKNPAAALPVILTRLKQKQDEWTKCREGFNVVWADVYAKNHYKSLDHRSFYFKQQDSKNLSAKALVSEVKDLKEKSQKEDDVVLSISAGYRQPIIPHLEYDYLDRAIHEDLFKLVQFSCEEICSTKEQTGKVLKLWANFLELMLDVAPRAKGSDSVEDVVETQHQRAFTSGEANESSDAISLVSRQLKFATNGDVHASSGVSKHGETGLLNRDSSGKENLKDGDLANKDVATCAEKPQKDQEIGNGAAKRSGDVDERVATSSSSFPSGVENNNGKVGSRDSSGSRGILSKPSEAIDKVDSIQHTQGVDIGRIIVLGNGLQSDTSKANSNYDESGGPSKIEKEEGELSPVGDSEDNFVVYEDRELKATAKTEHSVEAEGENDEDADDEDGDDASEAGEDASGTESIGDECSQDDNGVEEEGEHDEIDGKAESEGEAEGMESHLIEDKGLFPSSERVLLSVKPLSKHIAAAALVDEKKKDSRVFYGNDDFYVLFRLHRVSAIDSYDLLSHILYERILSAKTYCSGSEMKLRNTKDTCSPDPYARFMNALFSLLNGSAENSKFEDECRAIIGNQSYVLFTLEKLIYKLVKQLQAVVADDMDNKLLQLYEYENSRRPGRVFDSVYYENARILLHEENIYRLECSSSPSRLSIQLMDNIIEKPDAYAVSMEPTFTSYLQNEFLSNSSGKKELQDIVLQRNMRGYNGLDDLAVACKAMEGVQVINGLECKMSCSSYKISYVLDTEDFFHRKKKQKKSNNLSLAKLSQNRIARFHKFLSASR
Protein: Transcription factor TGA2.2 (OsNIF1) (OsbZIP1) (bZIP transcription factor 28) (OsbZIP28) (Q6IVC3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional regulator involved in defense response.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- BTB/POZ domain and ankyrin repeat-containing protein NPR1
- Os01g0104800 protein
- Os04g0662100 protein
- Os12g0166500 protein
- U3 small nucleolar RNA-associated protein 18 homolog
- DEAD-box ATP-dependent RNA helicase 36
- Pre-mRNA-splicing factor SLU7
- Os03g0598200 protein
- Os05g0295100 protein
- BTB/POZ domain and ankyrin repeat-containing protein NPR2
Sequence:
MADASSRTDTSTVLDTDDKNQMVDGQSGAIVPSNSSDRSDRSDKPMDQKVLRRLAQNREAARKSRLRKKAYVQQLESSKLKLASLEQEINKARQQGIYISSSGDQTHAMSGNGAMTFDLEYARWLEEQNKQINELRTAVNAHASDSDLRLIVDGIMAHYDEIFRLKGVAAKADVFHILSGMWKTPAERCFLWLGGFRSSELLKLLVNQLEPLTEQQLLGLSNLQQSSQQAEDALSQGMEALQQSLADTLAGSLGPSGSSGNVANYMGQMAMAMGKLGTLENFLRQADNLRQQTLHQMQRILTIRQAARALLAIHDYFSRLRALSSLWLARPRE
Protein: thioredoxin-disulfide reductase (EC 1.8.1.9) (A0A182DWF3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCCG
Protein: Calmodulin-like protein 12 (Touch-induced calmodulin-related protein 3) (P25071)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potential calcium sensor that binds calcium in vitro.
Interaction partners:
- Calcium-binding protein PBP1
- Probable calcium-binding protein CML46
- Xyloglucan endotransglucosylase/hydrolase protein 22
- Calcium-binding EF hand family protein
- At1g73440
Sequence:
MADKLTDDQITEYRESFRLFDKNGDGSITKKELGTMMRSIGEKPTKADLQDLMNEADLDGDGTIDFPEFLCVMAKNQGHDQAPRHTKKTMADKLTDDQITEYRESFRLFDKNGDGSITKKELRTVMFSLGKNRTKADLQDMMNEVDLDGDGTIDFPEFLYLMAKNQGHDQAPRHTKKTMVDYQLTDDQILEFREAFRVFDKNGDGYITVNELRTTMRSLGETQTKAELQDMINEADADGDGTISFSEFVCVMTGKMIDTQSKKETYRVVNQGQGQVQRHTRNDRAGGTNWERDIAVGVASNIIASPISDFMKDRFKDLFEALLS
Protein: Olfactory receptor (Q7TR79)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
Interaction partners:
Sequence:
MEKSNHSARIQVTEFILLGLTNNPGLKAPLFVIFLIIYLVTLMGNLGMVILTHVDSKLHTPMYFFLRHLSITDLGYSTVIGPKMMVNFVMQQNIISYTGCAVQLTFFEIFIITELFILSAMAYDRYVAICKPLLYVIIMAGKVRWGLVLVPYLYSLFVSLLLTVKLFTLSFCGSNIISYFYCDCVPLISLLCSDTHELELIILIFSGCNLLSSLLIVLVSYMFIFVAILRMNSKEGRSKAFSTCSSHLTVVVVFYGTLLFIYLQPKSSHTFEIDKMASVFYTLVIPMLNPLIYSLRNKEVKEALKRTLTQGLRIHT
Protein: Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase) (P06214)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P10518}.
Interaction partners:
- Porphobilinogen deaminase
- Uroporphyrinogen-III synthase
- 5-aminolevulinate synthase, non-specific, mitochondrial
- Uroporphyrinogen decarboxylase
- Ferrochelatase
- Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
- Amine oxidase
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
- Ornithine aminotransferase, mitochondrial
- Beta-alanine-activating enzyme
Sequence:
MHHQSVLHSGYFHPLLRAWQTTPSTVSATNLIYPIFVTDVPDDVQPIASLPGVARYGVNQLEEMLRPLVEAGLRCVLIFGVPSRVPKDEQGSAADSEDSPTIEAVRLLRKTFPTLLVACDVCLCPYTSHGHCGLLSENGAFLAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKAALLKHGLGNRVSVMSYSAKFASCFYGPFRDAAQSSPAFGDRRCYQLPPGARGLALRAVARDIQEGADILMVKPGLPYLDMVQEVKDKHPELPLAVYQVSGEFAMLWHGAKAGAFDLRTAVLESMTAFRRAGADIIITYFAPQLLKWLKEE
Protein: Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein) (Q9NP71)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- MLX-interacting protein
- Max-like protein X
- Peroxisome proliferator-activated receptor gamma coactivator 1-beta
- Transducin beta-like protein 2
- Max dimerization protein 4
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- 14-3-3 protein beta/alpha
- ATP-citrate synthase
- Sterol regulatory element-binding protein 1
- Hormone-sensitive lipase
Sequence:
MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSDSLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL
Protein: Transcriptional regulatory protein Fnr, global regulator of anaerobic growth (Q5E593)
Organism: Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
Interaction partners:
- Stress-induced protein
Sequence:
MMSDNSANKRIQSGGCAIHCQDCSISQLCIPFTLNDSELDQLDEIIERKKPIQKGQELFKAGDELKCLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITEAQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTRFHQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKTEMLTVKGKYITINDHDALAELAGSAKEIK
Protein: DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (B16) (P34087)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA. The RPB4-RPB7 subcomplex recruits FCP1 to Pol II.
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, P-body. Note=Seems to shuttle between nucleus and cytoplasm in a complex with RPB4.
Interaction partners:
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Transcription initiation factor IIE subunit alpha
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- Transcription initiation factor IIF subunit alpha
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- RNA polymerase II subunit B1 CTD phosphatase RTR1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerase II subunit RPB9
- Transcription initiation factor IIB
Sequence:
MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI
Protein: Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Q5D006)
Organism: Rattus norvegicus (Rat)
Function: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex; may act by deubiquitinating components of the PRC1-like comple. Promotes cell proliferation by deubiquitinating phosphorylated E2F1x.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P51784}. Cytoplasm {ECO:0000250|UniProtKB:P51784}. Chromosome {ECO:0000250|UniProtKB:P51784}. Note=Predominantly nuclear. Associates with chromatin. {ECO:0000250|UniProtKB:P51784}.
Interaction partners:
- NF-kappa-B inhibitor alpha
- Ubiquitin carboxyl-terminal hydrolase 7
- Breast cancer type 2 susceptibility protein homolog
Sequence:
MAAVAADPAAAAVPASAEDRETQPEAMPDLDQQWRQIGNGRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGSINNSGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLKDDQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYSDSVDLVLQTAREQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMNNMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDDGDEKGDENEDEDVEDDSSSEEEKEEMSGPTDNDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKNPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTASSETPTSPASSSTPNSDIMDVN
Protein: cDNA FLJ61235, weakly similar to WD repeat protein YBL104C (B4DGE7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSGTKPDILWAPHHVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWRPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECTEEENDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQSDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSETGSYDGVLYENKVAVRDRVAFACKFLSDTQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGTKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP
Protein: Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase) (Q86NZ5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU368116}.
Interaction partners:
Sequence:
TSNMCDRVREGILVGCGNPLLDISAVVPLNFLQKYSMNEDDAILAEDRHMPIYGELVEGYQAEFLAGGSVQNSLRIAQWILRQPRVAVFFGCVGEDRYANILKEKAQAAGLDVHYQVKKDVPTGTCAVLITGTHRSLCANLAAANNFTIDHLEEPSNKALVDNAQYYYISGFFLTVNPPSIMQVAATAHAKQRPFLMNLSAPFISQFYMAPLLAALPYVDIIFGNEAEAQAFAEAQQWPSGDLREIGKRLVAMEKKNPTRPRIAILTQGCDPVLLIQQDSVQEFPVTKLAVHEIVDTNGAGDAFVGGFLSQFVQGKSLDVCIRCGNYAAGHIIKNPGCTYSGEPEFVE
Protein: Autophagy-related protein 3, putative (C0H519)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Autophagy-related protein
- Ubiquitin-like protein ATG12
- Autophagy-related protein 7, putative
- ubiquitinyl hydrolase 1
- Autophagy-related protein 3, putative
- WD repeat-containing protein, putative
- Protein transport protein SEC22
- T-complex protein 1 subunit gamma
Sequence:
MSDQINVKHKIGDTCRKLYSYFKTVNNTSTFIQNGTLTPSEFVDSGDFLVYKFKTWEWQEADKDRVVPYLPENKQFLITKNVPCKQRIKDLNNIVHDLKIVDNDWLLPSYEEDNNPTDIYEYLPNSEYTINDKNIYNYEEEEEDDNCDEAIDINNFYMENNLIKEHDPASINSTSCYSKNMLHDNLMKIRTYDVSITYDKYYQTPRIWLFGYNENGDPLKSEEIFEDILSDYSYKTVTYDPHPCTGVMTASIHPCKHAEAILNVVNNWISEEKEPRHDLYLLFLLKFISGVIPTIEYDFTTDIEIPRDSNAGL
Protein: ORF123 (Q35303)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MDQDLLSLYGQYQSTKVDHMDVEKALDFVMNWKHLFSISIYLVHIFVSCVLGRNSISKEKVLEDFFNLSLADSPRYLDLPPPRSKLSSPAPLAGPEASSPLTDSSDSVKMKVISQKIGLSKTS
Protein: Small ribosomal subunit protein uS2m (28S ribosomal protein S2, mitochondrial) (MRP-S2) (S2mt) (Q9Y399)
Organism: Homo sapiens (Human)
Function: Required for mitoribosome formation and stability, and mitochondrial translation.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25838379}.
Interaction partners:
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein mS22
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein mS23
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS14m
Sequence:
MATSSAALPRILGAGARAPSRWLGFLGKATPRPARPSRRTLGSATALMIRESEDSTDFNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYLIENMARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNIFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQTAITRAKEKRQQVEALYRLQGQKEPGDQGPAHPPGADMSHSL
Protein: Replication protein A subunit (Q384B5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364130}.
Interaction partners:
- Replication Factor A 28 kDa subunit, putative
- DNA polymerase
- DNA repair protein RAD51 homolog
- DNA repair protein RAD50
- Uncharacterized protein
- DNA repair protein, putative
- DNA polymerase
- DNA primase large subunit
- RecQ mediated genome instability protein 1 OB-fold domain-containing protein
- Endo/exonuclease Mre11
Sequence:
MQQPSQQQIQPIDSLSPFLGGKWWIRARVTDKSEIRTWNKPTSQGKLFSFTLIDESASIRATVFNEAVDMFNPLIVNGQVYYFSGGQVKNANRKFSNVNNDYELSFDNTCQISAARDVVSSSIPLQRYNFVPIAILKQREVGSLVDVLAVVLNVEELGTIVQRSTGRELVRRTVKVADSTAGIDVTLWNENAKEWPHQPGTVLAMRQLKVGSFDGVTLSTTMQSSFDVNPNIPDVKKLREWFESTGGRDVSSLSMQGNNALGLASSGETYRGYKYIDDITTEGLGKGPKPDYIDLRCVPVYLKQDTQWYDACPQCNKKVMLEGAMGDRFRCEKCDQSIVPTQRYLVSIQVTDNVSQVWLTLFNESGAEFFGMTAPELKRRQEEDPMFVTKVAQMRMNRPVLMRLRVKEEGLGGNEDSERVRLNVVRITEFMPLDTVTEDKRQAMAAQLRQECDEMIKCINAYL