wanglab/gogpt-training-data huggingface dataset:
Protein: ER membrane protein complex subunit 1 (P25574)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Single-pass type I membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- ER membrane protein complex subunit 2
- ER membrane protein complex subunit 3
- ER membrane protein complex subunit 5
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 4
- Endoplasmic reticulum membrane protein complex subunit 10
- Protein SOP4
- Sec sixty-one protein homolog
- Mitochondrial import receptor subunit TOM5
Sequence:
MKITCTDLVYVFILLFLNTSCVQAVFSDDAFITDWQLANLGPWEKVIPDSRDRNRVLILSNPTETSCLVSSFNVSSGQILFRNVLPFTIDEIQLDSNDHNAMVCVNSSSNHWQKYDLHDWFLLEEGVDNAPSTTILPQSSYLNDQVSIKNNELHILDEQSKLAEWKLELPQGFNKVEYFHREDPLALVLNVNDTQYMGFSANGTELIPVWQRDEWLTNVVDYAVLDVFDSRDVELNKDMKAELDSNSLWNAYWLRLTTNWNRLINLLKENQFSPGRVFTKLLALDAKDTTVSDLKFGFAKILIVLTHDGFIGGLDMVNKGQLIWKLDLEIDQGVKMFWTDKNHDELVVFSHDGHYLTIEVTKDQPIIKSRSPLSERKTVDSVIRLNEHDHQYLIKFEDKDHLLFKLNPGKNTDVPIVANNHSSSHIFVTEHDTNGIYGYIIENDTVKQTWKKAVNSKEKMVAYSKRETTNLNTLGITLGDKSVLYKYLYPNLAAYLIANEEHHTITFNLIDTITGEILITQEHKDSPDFRFPMDIVFGEYWVVYSYFSSEPVPEQKLVVVELYESLTPDERLSNSSDNFSYDPLTGHINKPQFQTKQFIFPEIIKTMSISKTTDDITTKAIVMELENGQITYIPKLLLNARGKPAEEMAKDKKKEFMATPYTPVIPINDNFIITHFRNLLPGSDSQLISIPTNLESTSIICDLGLDVFCTRITPSGQFDLMSPTFEKGKLLITIFVLLVITYFIRPSVSNKKLKSQWLIK
Protein: SEC24 homolog C, COPII coat complex component (A0A286YDJ8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MNVNQSAPPVPPYGQNQPIYPGYHQSSYGGQPGPAAPATPYGAYNGPVPGYQQAPPQGVPRAPPSSGAPPASAAQVPCGQTTYGQFGQGDIQNGPSSTAQMQRVPGSQQFGPPLAPVVS
Protein: Ecdysone-induced protein 63E, isoform H (EC 2.7.11.22) (Serine/threonine protein kinase variant L63B3) (Q7KM04)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MREKKGGALQKLKKRLSHSFGRLTISREDGDESTHHHHHHHHHRGGHGGHHNHGNKVPYNGYNSEEYLDRLEPNGNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDRVQRQLSVSSDSKLLDEDIREEMKYHSHVVMRPKKPPRPKSEVFLNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEGVQLYTEPNRQNK
Protein: Myo-inositol transporter 1A (J9VTS6)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Major transporter for myo-inositol. Plays a role in the traversal of the host blood-brain barrier.
Subcellular location: Cell membrane {ECO:0000305|PubMed:21398509}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSDEKNYGISLAAPARPDLGSRTASQLEKATASHVEFATPKDPGALHDATLMAGERTEKLTKFVVGLALFASVSGFCFGFDTGVISAALVSIKDDFGHILDDTEKEWISAATSCGALVGALSSGALADRVGRKWTLAVGDVWFTLGAIIICSSFSVVQMIVGRAVLGLGVGTAAAIAPLYIAEVAPTRFRGALVTVQSIAITGGQFFSYCIGIPLTGHNGWRIQFAIGIVPAVVQAAVVHFLPESPRYDLLRGQREAALATIHRSYKGMSEDYIAVKFAALEEVVGISADFNRGHTLGQKMRLVLTEGKYRKPAITALGIGIFQQLCGFNSLMYYAATIFSYAGFDNPTSVGLIVSGTNWFFTFVAMMILDRVGKRRILLSTYPGMIAGLALASVAFWKMTGSTGHRLVEGTEYPQQWSNMMLGMMVVFIAFYATGSGNITWTVGEMFPLEMRGIGASILAGGVWAANIVISATFLTLMNAIGPTPTFALYAGICLAGLIFIYFCYPEPSGLSLEEIQIIYNYGFGVQKSREIRAEHKLKAQEMRDRANSHIGGSATASDDQLNKV
Protein: Cellulose synthase A catalytic subunit 4 [UDP-forming] (EC 2.4.1.12) (OsCesA4) (Q5JN63)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation (By similarity). Involved in the secondary cell wall formation.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cellulose synthase A catalytic subunit 9
- Cellulose synthase A catalytic subunit 7
- dihydroxy-acid dehydratase
- Os05g0103600 protein
- Os12g0599900 protein
- Os09g0123500 protein
- Os01g0189100 protein
- Os03g0679800 protein
- Os12g0636100 protein
- Os03g0680600 protein
Sequence:
MMESGVPPCAACGDDAHAACRACSYALCKACLDEDAAEGRTTCARCGGEYGAPDPAHGQGAVVEEEVEESHEPAAGGVRERVTMASQLSDHQDEGVHARTMSTHARTISSVSGVGSELNDESGKPIWKNRVESWKEKKKEKKASAKKAAAKAQAPPVEEQIMDEKDLTDAYEPLSRIIPISKNKLTPYRAVIIMRLVVLGLFFHYRITNPVYSAFGLWMTSVICEIWFGFSWILDQFPKWCPINRETYVDRLIARYGDGEDSGLAPVDFFVSTVDPLKEPPLITANTVLSILAVDYPVEKISCYVSDDGSAMLTFESLAETAEFARRWVPFCKKYSIEPRAPEFYFSQKIDYLKDKIHPSFVKERRAMKRDYEEYKVRINALVAKAQKTPEEGWIMQDGTPWPGNNPRDHPGMIQVFLGETGARDFDGNELPRLVYVSREKRPGYQHHKKAGAMNALVRVSAVLTNAPYILNLDCDHYVNNSKAVREAMCFMMDPSVGRDVCYVQFPQRFDGIDRSDRYANRNVVFFDVNMKGLDGLQGPVYVGTGCCFYRQALYGYGPPSLPALPKSSVCSWCCCCCPKKKAEKSEKEMHRDSRREDLESAIFNLREIDNYDEYERSMLISQMSFEKSFGLSSVFIESTLMENGGVPESANPSTLIKEAIHVISCGYEEKTEWGKEIGWIYGSVTEDILTGFKMHCRGWRSIYCMPIRPAFKGSAPINLSDRLHQVLRWALGSVEIFLSRHCPLWYGYGGGRLKWLQRLSYINTIVYPFTSLPLIAYCCLPAICLLTGKFIIPTLSNAATIWFLGLFISIIVTSVLELRWSGIGIEDWWRNEQFWVIGGVSAHLFAVFQGILKMIAGLDTNFTVTAKATDDTEFGELYVFKWTTVLIPPTSILVLNLVGVVAGFSDALNSGYESWGPLFGKVFFAMWVIMHLYPFLKGLMGRQNRTPTIVVLWSVLLASVFSLLWVKIDPFIGSSETTTTNSCANFDC
Protein: Protein transport protein SEC31 homolog B (SEC31-like protein B) (Q8L611)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for protein transport from the endoplasmic reticulum to the Golgi apparatus.
Subcellular location: Golgi apparatus {ECO:0000305|PubMed:24280388}. Endoplasmic reticulum {ECO:0000305|PubMed:24280388}.
Interaction partners:
- Protein transport protein SEC13 homolog A
- Protein transport protein SEC13 homolog B
- Protein transport protein SEC24 A
- Protein transport protein SEC23 D
- Protein transport protein SEC24 C
- Small COPII coat GTPase SAR1B
- Protein transport protein SEC23
- Protein transport protein SEC16A homolog
- Ras-related small GTP-binding family protein
- Protein transport protein SEC23 G
Sequence:
MACIKGVGRSASVALAPDAPYMAAGTMAGAVDLSFSSSANLEIFKLDFQSDDRDLPLVGEIPSSERFNRLAWGRNGSGSEEFALGLIAGGLVDGNIDLWNPLSLIGSQPSENALVGHLSVHKGPVRGLEFNAISSNLLASGADDGEICIWDLLKPSEPSHFPLLKGSGSATQGEISFISWNRKVQQILASTSYNGTTVIWDLRKQKPIINFADSVRRRCSVLQWNPNVTTQIMVASDDDSSPTLKLWDMRNIMSPVREFTGHQRGVIAMEWCPSDSSYLLTCAKDNRTICWDTNTAEIVAELPAGNNWNFDVHWYPKIPGVISASSFDGKIGIYNIEGCSRYGVEENNFGTAPLKAPKWYKRPVGASFGFGGKLVSCHARAPAKGTSSILSEVFLHSLVTEQSLVSRTSEFEAAIENGDMTSLRGLCEKKSEETESEEEKETWGLLKIMFEEEGTSRTKLISHLGFTLPVAEKDQAVDGLSSDLNGIRLEDTAADALDLDDSNEAAAFAMDNGEDFFNNFPAKPDTPVSTSAKDFMPSDTDFSTKGEETQEMQEEEEESSDPVFDNAIQRALIVGDYKEAVDQCITANKMADALVIAHVGGTALWESTREKYLKTSSAPYMKVVSAMVNNDLRSLIYTRSHKFWKETLALLCTFAQGEQWTTLCDALASKLMAAGNTLAAVLCYICAGNVDRTVEIWSRSLANERDGRSYAELLQDLMEKTLVLALATGNKKFSASLCKLFESYAEILASQGLLTTAMKYLKVLDSGGLSPELSILRDRISLSAEPETNTTASGNTQPQSTMPYNQEPTQAQPNVLANPYDNQYQQPYTDSYYVPQVSHPPMQQPTMFMPHQAQPAPQPSFTPAPTSNAQPSMRTTFVPSTPPALKNADQYQQPTMSSHSFTGPSNNAYPVPPGPGQYAPSGPSQLGQYPNPKMPQVVAPAAGPIGFTPMATPGVAPRSVQPASPPTQQAAAQAAPAPATPPPTVQTADTSNVPAHQKPVIATLTRLFNETSEALGGARANTTKKREIEDNSRKLGALFVKLNSGDISKNAADKLAQLCQALDNNDFSTALQIQVLLTTSEWDECNFWLATLKRMMVKARQNVR
Protein: Probable serine/threonine-protein kinase PIX13 (EC 2.7.11.1) (Q9SII6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in plant defense signaling.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21219905}; Lipid-anchor {ECO:0000305|PubMed:21219905}. Nucleus {ECO:0000269|PubMed:21219905}. Note=Predominantly localized at the plasma membrane. {ECO:0000269|PubMed:21219905}.
Interaction partners:
- Plasma membrane fusion protein
- Transmembrane protein
- Large ribosomal subunit protein P2z
- 28 kDa heat/acid-stable phosphoprotein-like protein
- Thiosulfate/3-mercaptopyruvate sulfurtransferase 2
- Ureide permease 5
- Probable WRKY transcription factor 53
- Probable protein phosphatase 2C 52
- Probable inorganic phosphate transporter 1-3
Sequence:
MGLCWGSPSDSPPTTTPSSTGNISSVGTFKSSNNTTTTGTSRGSNISSNSGFSVASGEDAYPDGQILPIPNLRIFSLAELRASTRNFRSENVLGEGGFGKVFKGWLEDKTPGKQSNGTVIAVKKLNAESFQGFEEWQCEVNFLGRVSHPNLVKLLGYCLEGEELLLVYEYMQKGSLENHLFRKGSAVQPLSWEIRLKIAIGAAKGLAFLHASEKQVIYRDFKASNILLDGSYNAKISDFGLAKLGPSASQSHITTRVMGTHGYAAPEYVATGHLYVKSDVYGFGVVLAEILTGLHALDPTRPTGQHNLTEWIKPHLSERRKLRSIMDPRLEGKYPFKSAFRVAQLALKCLGPEPKNRPSMKEVVESLELIEAANEKPLERRTTRASPSIRQQQGHYRPQQLSSFRPRQNVSRAH
Protein: P3 protein (Solute carrier family 10 member 3) (P21129)
Organism: Mus musculus (Mouse)
Function: The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Ubiquitin-like protein 4A
- Sodium/bile acid cotransporter 7
Sequence:
MVVKKSRGSSQQLPGLGGQGGCTGFVGMLGTALLFISLPWGAQVMASANISTALGHTSGHYLSIGDGSVTEFDFPEKSEGIIVISSQYTGQTNGTGPSPILKVISLDTEVLTIKNVSAITWSSGGGFVVGIHSGLAGLAPLHLQLMDFYEAPPLLIEERRDFCIRVSPAEDLPSALNTNLGHFSENPILYLLLPLIFVNKCSFGCKVELEVLKELLQSPQPMLLGLLGQFLVMPFYAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFISTVAATGFLPLSSAIYSYLLSIHETLHVPISKILGTLLFIAIPIAAGVVIKSKLPKFSELLLQVIKPFSFILLLGGLFLAYHMGVFILVGVRLPIVLVGFTVPLVGLLVGYSLAICLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGQFIYSILFPVP
Protein: Pterin deaminase (PDA) (EC 3.5.4.11) (B9J8S0)
Organism: Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter)
Function: Catalyzes the deamination of many pterin metabolites, such as formylpterin, pterin-6-carboxylate, pterin-7-carboxylate, pterin, hydroxymethylpterin, biopterin, D-(+)-neopterin, isoxanthopterin, sepiapterin, folate, xanthopterin, and 7,8-dihydrohydroxymethylpterin. May be involved in a degradative pathway for catabolizing pterin rings.
Interaction partners:
- Creatininase
- Creatinine amidohydrolase
- FAD linked oxidase protein
- dihydrouracil dehydrogenase
- Uracil phosphoribosyltransferase
- Creatininase
- NAD
- Purine nucleoside phosphorylase
- Thymidine phosphorylase
- Uridine phosphorylase
Sequence:
MSYSFMSPPNAARFVLSNATVPAVTVVGFTGPSSEGLMKADIVVADGLIKDILPAGTAPAELAKADMRDGMVWPTFADMHTHLDKGHIWERRANPDGSFMGALDAVRSDREANWSAADVRKRMEFSLRAAYAHGTSLIRTHLDSLAPQHRISFEVFSEVREAWKDKIALQAVALFPLDFMVDDAFFADLTTVVREAGGLLGGVTQMNPDIDAQLDKLIRAAAANGLDIDLHVDETEDREVLTLKAIAAAVLRNGFTGKVTAGHCCSLARQDENVAAATIDLVAKAGISIVALPMCNMYLQDRHPGRTPRWRGVTLLHELAAAGVPTAVASDNTRDPFYAYGDLDPVEVFREAVRILHLDHPLDTAARVVTTSPASILGRPDIGRIAVGGPADLVLFSARRWSEFLSRPQSDRVVLRKGKVIDRSLPDYRELDTVIGA
Protein: Multiplexin, isoform E (Q86BH1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAMVISTRAKLVITALILFFLLGIVLVTGSTKGWFNPNRYNGERVAARIQATDIFDASGMQPPGQTQYTHERPYRGIKGEKGERGPKGDSIRGPPGPPGPPGPKGETAPYPPFVETTSAGAKYTGECTCNASDILEAIKDNESLRESLRGAPGTPGKDGKPGTPGHTGATGVPGARGARGSEGAQGLKGEPGVDGLPGVMGPPGPPGPPGLPENYDESLMVNSMGAFRGTTQPGAKGVPGEKGDAGQKGERGDPGHKGAHGPSGAKGEPGEPGTPGLPGLPGQVGQPGGLDGLASANGTKGEKGEKGEKGMRGRRGGTGATGPIGPPGKPGPMGDIGHSGRPGMTGPKGEMGPKGPKGDSGGREGLKGDKGDRGQDGRDGLPGPPGLPSTGGGDGDSGGVQYIPMPGPPGPPGPPGLPGLSISGPKGEPGVDSRSSFFGDASYYGRPEPPRQPGHSHKHEETLGLVDGEEPYFSASSSNMNMKIVPGAVTFQNIDEMTKKSALNPPGTLAYITEEEALLVRVNKGWQYIALGTLVPIATPAPPTTVAPSMRFDLQSKNLLNSPPPLLNTPTLRVAALNEPSTGDLQGIRGADFACYRQGRRAGLLGTFKAFLSSRVQNLDTIVRPADRDLPVVNTRGDVLFNSWKGIFNGQGGFFSQAPRIYSFSGKNVMTDSTWPMKMVWHGSLPNGERSMDTYCDAWHSGDHLKGSFASNLDGHKLLEQKRQSCDSKLIILCVEALSQDRKRKKREIGDGSSHGESESREFKTADEYAAHLENLLL
Protein: Integrator complex subunit 4 (Int4) (Q96HW7)
Organism: Homo sapiens (Human)
Function: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:23904267, ECO:0000269|PubMed:29471365, ECO:0000269|PubMed:39032489, ECO:0000269|PubMed:39032490}. Cytoplasm {ECO:0000269|PubMed:29471365}.
Interaction partners:
- Integrator complex subunit 11
- Integrator complex subunit 6
- Integrator complex subunit 3
- Integrator complex subunit 9
- Integrator complex subunit 5
- Integrator complex subunit 1
- Integrator complex subunit 7
- Integrator complex subunit 2
- Integrator complex subunit 8
- Integrator complex subunit 10
Sequence:
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSAVSPSIIPQEDPSQQFLQQSLERVYSLQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQSAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVYLSHTAWTEACQVEVRLLLAYNSSARIPKCPWMEGGEMSPQVETSIEGTIPFSKPVKVYIMPKPARR
Protein: T:G mismatch thymine glycosylase (Q99NG8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MMAEAPNMADVAGQQMPAEAPAQDPVPEAPKRRKRKTRAAEAQDPVEPKKPAASKKSGKSTKSKEKQEKITDTFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLSHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERSTDVQEVQYTFDLQLAQEDAKRTAVKEEKYDPGYEAAYGGACGENPCNGEPCGFASNGLTANSAELGGESAPSDVPNGQWMAQSFAEQIPSFNNCGTGEQEAGSHAGSHA
Protein: Achaete-scute homolog 3 (ASH-3) (mASH-3) (mASH3) (bHLH transcriptional regulator Sgn-1) (Q9JJR7)
Organism: Mus musculus (Mouse)
Function: Transcriptional repressor. Inhibits myogenesis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
Sequence:
MDTRSYPSPPDRLSVFAESAHLPLSRPFYLDPMVTVHLCPETPVPASYTDELPLLPFSSDTLIMNNYGDPYPFPFPMPYTNYRRCDYTYGPAFIRKRNERERQRVKCVNEGYARLRRHLPEDYLEKRLSKVETLRAAIKYISYLQSLLYPDESETKKNPRTASCGSLDPALRVI
Protein: Growth/differentiation factor 8 (GDF-8) (Myostatin) (Myostatin-1) (zfMSTN-1) (Myostatin-B) (O42222)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Acts specifically as a negative regulator of skeletal muscle growth. May down-regulate muscle-specific transcription factors such as myod and myog.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- Receptor protein serine/threonine kinase
- Follistatin 2
- Follistatin-A
- Serine/threonine-protein kinase receptor
- Serine/threonine-protein kinase receptor
- receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- Growth/differentiation factor 8
Sequence:
MHFTQVLISLSVLIACGPVGYGDITAHQQPSTATEESEQCSTCEFRQHSKLMRLHAIKSQILSKLRLKQAPNISRDVVKQLLPKAPPLQQLLDQYDVLGDDSKDGAVEEDDEHATTETIMTMATEPDPIVQVDRKPKCCFFSFSPKIQANRIVRAQLWVHLRPAEEATTVFLQISRLMPVKDGGRHRIRSLKIDVNAGVTSWQSIDVKQVLTVWLKQPETNRGIEINAYDAKGNDLAVTSTETGEDGLLPFMEVKISEGPKRIRRDSGLDCDENSSESRCCRYPLTVDFEDFGWDWIIAPKRYKANYCSGECDYMYLQKYPHTHLVNKASPRGTAGPCCTPTKMSPINMLYFNGKEQIIYGKIPSMVVDRCGCS
Protein: Superinfection exclusion protein B (P38392)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Interaction partners:
- Uncharacterized protein YciQ
- Uncharacterized protein YehI
Sequence:
MLDVFTPLLKLFANEPLERLMYTIIIFGLTLWLIPKEFTVAFNAYTEIPWLFQIIVFAFSFVVAISFSRLRAHIQKHYSLLPEQRVLLRLSEKEIAVFKDFLKTGNLIITSPCRNPVMKKLERKGIIQHQSDSANCSYYLVTEKYSHFMKLFWNSRSRRFNR
Protein: Paired box protein Pax-6 (Protein eyeless) (O18381)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in eye morphogenesis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00381, ECO:0000269|PubMed:7914031}.
Interaction partners:
- GEO11848p1
- Protein doublesex
- Protein tiptop
- Protein phosphatase eya
- Dachshund, isoform B
- Protein sine oculis
- Protein distal antenna
- GH14454p
Sequence:
MRNLPCLGTAGGSGLGGIAGKPSPTMEAVEASTASHRHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAASSASANVTPHHTIAQESCPSPCSSASHFGVAHSSGFSSDPISPAVSSYAHMSYNYASSANTMTPSSASGTSAHVAPGKQQFFASCFYSPWV
Protein: At1g07135 (F10K1.16 protein) (Glycine-rich protein) (Predicted GPI-anchored protein) (Q9LMK6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Gb|AAC02775.1
- AT3g02480/F16B3_11
- Expansin-like A1
- Protein PLANT CADMIUM RESISTANCE 1
- Transcription factor bHLH92
Sequence:
MGLRRTWLVLYILFIFHLQHNLPSVSSRPSSVDTNHETLPFSVSKPDVVVFEGKARELAVVIKKGGGGGGGGRGGGGARSGGRSRGGGGGSSSSRSRDWKRGGGVVPIHTGGGNGSLGGGSAGSHRSSGSMNLRGTMCAVCWLALSVLAGLVLVQ
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (E7ESZ7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305, ECO:0000256|PIRNR:PIRNR000543}.
Interaction partners:
Sequence:
MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDDPRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIRKQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENAYKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELGIPYPQRAVQSTREGPEVLLTGLWRWEDLLIGLQLPGRKYSPGYNTEVGDKWIWLK
Protein: Probable glutaredoxin ssr2061 (P73492)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity).
Interaction partners:
- Ribonucleoside-diphosphate reductase subunit alpha
- Slr0600 protein
- Glutathione synthetase
- Glutaredoxin arsenate reductase
Sequence:
MAVSAKIEIYTWSTCPFCMRALALLKRKGVEFQEYCIDGDNEAREAMAARANGKRSLPQIFIDDQHIGGCDDIYALDGAGKLDPLLHS
Protein: Chaperone protein ClpC1, chloroplastic (ATP-dependent Clp protease ATP-binding subunit ClpC homolog 1) (Casein lytic proteinase C1) (Protein DE-REGULATED CAO ACCUMULATION 1) (Protein IRON-RESCUED MUTANT 1) (Q9FI56)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Molecular chaperone that hydrolyzes ATP and is associated with the chloroplast protein import apparatus. May function as the motor for chloroplast protein translocation, as translocation requires ATP hydrolysis in the stroma. May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast. Involved in the regulation of chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase (CAO) protein in response to the accumulation of chlorophyll b. Involved in leaf iron homeostasis.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:11982939, ECO:0000269|PubMed:14593120, ECO:0000269|PubMed:20382967, ECO:0000269|PubMed:24599948}. Plastid, chloroplast membrane {ECO:0000269|PubMed:24599948}. Note=The membrane association is important for the in vivo functions. {ECO:0000269|PubMed:24599948}.
Interaction partners:
- Protein TIC 40, chloroplastic
- Protein TIC110, chloroplastic
- ATP-dependent Clp protease proteolytic subunit 3, chloroplastic
- ATP-dependent Clp protease proteolytic subunit-related protein 1, chloroplastic
- ATP-dependent Clp protease proteolytic subunit 6, chloroplastic
- ATP-dependent Clp protease adapter protein CLPS1
- ATP-dependent Clp protease proteolytic subunit-related protein 2, chloroplastic
- Clp protease adapter protein ClpF
- Chloroplastic ATP-dependent Clp protease proteolytic subunit 1
- ATP-dependent Clp protease proteolytic subunit-related protein 4, chloroplastic
Sequence:
MAMATRVLAQSTPPSLACYQRNVPSRGSGRSRRSVKMMCSQLQVSGLRMQGFMGLRGNNALDTLGKSRQDFHSKVRQAMNVPKGKASRFTVKAMFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGIAAKVLKSMGINLKDARVEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGSEHLLLGLLREGEGVAARVLENLGADPSNIRTQVIRMVGENNEVTANVGGGSSSNKMPTLEEYGTNLTKLAEEGKLDPVVGRQPQIERVVQILGRRTKNNPCLIGEPGVGKTAIAEGLAQRIASGDVPETIEGKKVITLDMGLLVAGTKYRGEFEERLKKLMEEIRQSDEIILFIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIEKDPALERRFQPVKVPEPTVDETIQILKGLRERYEIHHKLRYTDESLVAAAQLSYQYISDRFLPDKAIDLIDEAGSRVRLRHAQVPEEARELEKELRQITKEKNEAVRGQDFEKAGTLRDREIELRAEVSAIQAKGKEMSKAESETGEEGPMVTESDIQHIVSSWTGIPVEKVSTDESDRLLKMEETLHKRIIGQDEAVKAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKSELAKALAAYYFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGYTEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMMLQILEDGRLTDSKGRTVDFKNTLLIMTSNVGSSVIEKGGRRIGFDLDYDEKDSSYNRIKSLVTEELKQYFRPEFLNRLDEMIVFRQLTKLEVKEIADILLKEVFERLKKKEIELQVTERFKERVVDEGYNPSYGARPLRRAIMRLLEDSMAEKMLAREIKEGDSVIVDVDAEGNVTVLNGGSGTPTTSLEEQEDSLPVA
Protein: dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46) (P27830)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.
Interaction partners:
- Glucose-1-phosphate thymidylyltransferase 2
- Glucose-1-phosphate thymidylyltransferase 1
- UDP-N-acetyl-D-mannosamine dehydrogenase
- dTDP-4-dehydrorhamnose 3,5-epimerase
- dTDP-4-amino-4,6-dideoxygalactose transaminase
- dTDP-4-dehydrorhamnose reductase
- UDP-N-acetylglucosamine 2-epimerase
- dTDP-fucosamine acetyltransferase
- Lipid III flippase
- ECA polysaccharide chain length modulation protein
Sequence:
MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYGNGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPNKPHGVAHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLANESWWKQVQDGSYQGERLGLKG
Protein: Transcriptional regulator (A0A0H2UPA1)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAFDVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCSYGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDDKGQRHFVIRQK