wanglab/gogpt-training-data huggingface dataset:
Protein: ATP synthase protein YMF19 (EC 7.1.2.2) (Mitochondrial protein YMF19) (P93303)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This is one of the chains of the nonenzymatic component (CF(0) subunit) of the mitochondrial ATPase complex.
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:14671022}; Single-pass membrane protein {ECO:0000269|PubMed:14671022}.
Interaction partners:
- ATP synthase subunit delta', mitochondrial
- ATP synthase protein MI25
- ATP synthase subunit b, chloroplastic
- ATP synthase subunit 9
- Probable ATP synthase 24 kDa subunit
- ATP synthase subunit beta-3, mitochondrial
- ATP synthase subunit beta-2, mitochondrial
- AT4g32260/F10M6_100)
- ATP synthase subunit alpha
- ATP synthase subunit d, mitochondrial
Sequence:
MPQLDKFTYFSQFFWLCLFFFTFYIFICNDGDGVLGISRILKLRNQLLSHRGKTIRSKDPNSLEDLLRKGFSTGVSYMYASLFEVSQWCKAVDLLGKRRKITLISCFGEISGSRGMERNILYNISKSSPSNTGRWITCRNCRNDIMLIHVVHGQGSIK
Protein: Large ribosomal subunit protein eL39y (60S ribosomal protein L39-2) (Q8L8W6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein eL29y
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein eL29z
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL31z
- Large ribosomal subunit protein eL33y
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Large ribosomal subunit protein uL23y
Sequence:
MPSHKSFMIKKKLGKKMRQNRPIPNWIRLRTDNKIRYNAKRRHWRRTKLGF
Protein: Carboxysome assembly protein CcmM (CcmM73) (M73) (Carbon dioxide concentrating mechanism protein CcmM) (P72758)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Functions as a scaffold protein for the assembly of beta-carboxysomes, initiates carboxysome assembly via its N-terminal domain binding to CcaA, CcmK and CcmL. Binds HCO(3)-, suggesting it may play a role in the activity or regulation of bicarbonate dehydration. Also initiates carboxysome assembly by coalescing RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) via its SSU-like domains. Produced as a full-length and a shorter form; both forms are required for correct carboxysome assembly and growth (By similarity). Despite its strong similarity to gamma-class carbonic anhydrase (CA) it does not have detectable CA activity.
Subcellular location: Carboxysome {ECO:0000269|PubMed:17993516}. Note=This cyanobacterium makes beta-type carboxysomes. Full length protein associates with the shell portion of carboxysomes, CcmM52 associates with both the soluble and shell portion of carboxysomes. {ECO:0000269|PubMed:17993516}.
Interaction partners:
- Carboxysome assembly protein CcmN
- Ribulose bisphosphate carboxylase large chain
- Carboxysome shell vertex protein CcmL
- Carboxysome shell protein CcmK1
- Carbonic anhydrase
- Ribulose bisphosphate carboxylase small subunit
- Carboxysome shell protein CcmK3
- carbonic anhydrase
- Carboxysome shell protein CcmK2
- Carboxysome shell protein CcmK4
Sequence:
MLAKSLGWLLAVSRRNYCMGSRTALASRPWSKHLADPQIDPTAYVHSFANVVGDVRIQPGVSVAPGSSIRADEGTPFWIGGNVLIQHGVVIHGLETGRVLGDDDQEYSVWIGPGTCVAHLALVHGPVYLGANCFIGFRSTVLNARVGDGAVVMMHSLVQDVEIPPNKLVPSGAMITQQHQADSLPDVQAGDRHFVQQIAAMHGQSASPTQGTDPTVCVLPESLPAVTPVTETPYINSIDNMSINSDITNQIRSLLAQGYGIGAEHANERRFKTKSWQSCGTADGFRPDQVIATVEGWLQEFAGEYVRLIGIDQGAKRRVVEVIIQRPGDVPGSPSRGTTTTKALSSGGSGRSAVAHQTGNLAGDSANQLRALLHQGYKIGLEYASARRFKTGSWLTGGTIGSHREGEALQELNRFLADHTNEYVRIIGIDPAGKRRVAEIVVHRPNGNGNGKPSSSSSSVGYKSAPVSSAGGSSAGGLTPEVIATVRGLLANGHSIGTEHTDKRRFKAKSWDTCPTIDGGREAEVLAKLEACLADHAGEYVRIIGIDRVGKRRVLEQIIQRPGDNVVAGRSPSSSSASTSSSASSNGFGSGNGGGYSNSAVRLDNSVVTQVRSLLAQGYKIGTEHTDKRRFKAKSWQSCAPITSTHESEVLRALEGCLADHNGEYVRLLGIDPTAKRRVLETIIQRP
Protein: SD03430p (Q95TH6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLHSQTMQSIPTLHQPLHSKVSNYLNNQRRTGQFCDLLLELDSDDSLSLSVHFCVLAAQSQFINSNQKQQQFSIHNPLKITIRNFSCTQCLHTIVDFFYEDLVSVSKEHELHFRELAQILAVTELLNLYQLQPLGEAKEATEIPAPGEAQPNPDPEKKAEAVFENRQSYFKLKNPRAVKSSSKVNYCIGCDFKCYQVQKMIEHMGSCEPSHLICSLCEVGFLDWREYDSHLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTETPHICPHCGKGFKWKQGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEFFACTVSGCKHRANRKENLKLHIETHKQGRDFICEVCGCKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKEHVQRVHTEKPVQLELSETVDSSFPDDFELPVIETSPKKKPKSVKSKTIRNVNPDKRLKTLLPKETVE
Protein: Protein PET20, mitochondrial (Petite colonies protein 20) (Q99373)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for respiratory growth, stability of the mitochondrial genome and for proper assembly or maintenance of mitochondrial proteins.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16491469}.
Interaction partners:
- Probable ADP-ribose 1''-phosphate phosphatase YML087W
- MIOREX complex component 6
- ADP-ribosylation factor-like protein 3
- Large ribosomal subunit protein bL34m
- Small ribosomal subunit protein uS5m
- Large ribosomal subunit protein mL61
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein uL23m
- Large ribosomal subunit protein uL15m
Sequence:
MLKLARPFIPPLSRNNAISSGIVLTSRRFQSSFTFLSNQSLLSKNQMKSKRKKGSKKAAYHRQPPEHEHTAPLIKQNKTITKKEHSDVRGSHLKKKRSDFSWLPRVPSTSHLKQSDMTTNVLYSGYRPLFINPNDPKLKEDTGSTLYEFAMKLEDLNEPLSPWISSATGLEFFSEWENIPSELLKNLKPFHPPKEKSMNTNELIHVSAKRNTLVDNKTSETLQRKMDEFSKRRGKGRKKSVVTLLQMKKKLEG
Protein: Histone acetyltransferase HAC5 (EC 2.3.1.48) (Q9LE42)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histone acetyltransferase of the MYST family 2
- Histone acetyltransferase GCN5
- Transcription initiation factor TFIID subunit 1b
- Histone acetyltransferase of the MYST family 1
- Transcription initiation factor TFIID subunit 1
- Mediator of RNA polymerase II transcription subunit 15a
- Probable mediator of RNA polymerase II transcription subunit 15c
- Mediator of RNA polymerase II transcription subunit 19a
- Mediator of RNA polymerase II transcription subunit 25
- Probable transcription factor PosF21
Sequence:
MAQGQNRTVLQSGQMHNSVVASASSVSSQPNMVNGISQDTLLLRQEMLNRTYAWLQQRQPSKTDDASKAKLSEVAKRLESAMWRTATSKEDYLDFRSFDVRVESTLKQLLSQRRANPSSSVSTMVQTPGVSHGWGQSYTATPMVDTSKFNSSNNLSDATTETGRLLPTNRMYRGTINNGRQELSAVGQMIPTPGFDNSANADVYQSHRNEEYSGDGGKLLATGSDFGNPSQLQKQRPTGSNDLMGYNLDHQLGGGFRSNIHQNTSGMTSIPLNAGVGMSGNNVHLANVPRSSEGVLSSTHFSTFSQPSQQPVEQLQVSHVNRYSMSNSGTFVSGNLYGVQTSSGSIETAVDMNSMSLNSMRRVDTSFGSQSGLQNNPLLKPHLRHQFENGNFQSSSNSKENLAQVSHRPLERQFNQQAHYGQYHQQELLMNNDAYRQSQPASNLVSQVKNEPRVEYYNEAFQMQAINKVEPSKPQNQYKQNTVKDEYVGAQSAPVSSSQLKMSPSFPPQTHQTQQVSQWKDSSSLSAGVQPVSGLGQWHSSSQNLTPISKNSNEEREHFGVRFHKQHEGTNNSSSVRESTNCLTVAPSGTLDVPHLPVGINVLSKQLNGDCGLSYKNQRRWLLFLLHVRKCNAAEDNCESKYCFTAKTLLKHINCCKAPACAYQYCHQTRQLIHHYKHCGDEACPVCVFVKNFKEKQKEKFTFLQRAEPSSASLNHGPKESFESMRTSSERDSEAPFVVDDLQPSPKRQKVEKPSQFAYPDTQGNPATISAGVSQAHFSMGLQEKDRLPSDVCKPVRSNVPMNADSSDSSRRLVPVSRELEKPVCKDTHMGRHGVKSALDGESLRLSKQEKPKRMNEISAPKEENAEQSLGVVSASNCGKSKIKGVSLIELFTPEQVEEHIRGLRQWVGQSKTKAEKNKAMGLSMSENSCQLCAVERLAFEPTPIYCTPCGARVKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTPVPKSRFEKKKNDEEVEESWVQCDKCQAWQHQICALFNGRRNHGQAEYTCPNCYIQEVEQGERKPVSQNVILGAKSLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPGADSLVIRVVASVDKILEVKPRFLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLFGMYVQEFGTDSASPNQRRVYLSYLDSVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKKRGFSSCYIWACPPLKGEDYILYCHPEIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFYDHFFVQSGECRAKVTAARLPYFDGDYWPGAAEDLIDQMSQEEDGKKSNRKLMPKKVISKRALKAVGQLDLSVNASKDLLLMHKLGEIILPMKEDFIMVHLQHCCKHCCTLMVSGNRWVCNQCKNFQICDKCHEVEENRVEKEKHPVNQKEKHVLYPVAIDNIPTEIKDNDDILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWRCEVCPDYDVCNACYSKGINHPHSIISRPSATDSVVQNTQTNQIQNAQLREVLLHVMTCCTAQCQYPRCRVIKGLIRHGLVCKTRGCIACKKMWSLFRLHSRNCRDPQCKVPKCRELRAHFSRKQQQADSRRRAAVMEMVRQRAADTTASTPE
Protein: Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (Q803C3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Also functions as deacetylase for non-histone targets. In addition to protein deacetylase activity, also acts as protein-lysine deacylase by recognizing other acyl groups: catalyzes removal of (2E)-butenoyl (crotonyl) and 2-hydroxyisobutanoyl (2-hydroxyisobutyryl) acyl groups from lysine residues, leading to protein decrotonylation and de-2-hydroxyisobutyrylation, respectively.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O15379}. Chromosome {ECO:0000250|UniProtKB:O15379}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:O15379}.
Interaction partners:
- Nuclear receptor corepressor 2
- Nuclear receptor corepressor 1.
- F-box-like/WD repeat-containing protein TBL1X
- F-box-like/WD repeat-containing protein TBL1XR1a
- Si:ch211-262i1.5
- Si:ch211-9d9.1.
- AT-rich interactive domain-containing protein 4B
- AT-rich interactive domain-containing protein 4A
- G protein pathway suppressor 2
- Mortality factor 4-like protein 1
Sequence:
MTNRTAYFYDPDVGNFHYGAGHPMKPHRLSLTHSLVLHYGLYKKMMVFKPYKASQHDMCRFHSEDYIDFLQKVSPNNMQGFTKSLNTFNVGGDCPVFPGLFEFCSRYTGASLQGATQLNHKICDIAINWAGGLHHAKKFEASGFCYVNDIVISILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYRQLFQPVIKQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEFVKGFKIPLLVLGGGGYTVRNVARCWTFETSLLVEESISDELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLEQIRQTVFENLKMLNHAPSVQIRDVPSDLLSYERPDEADPEERGSEENFSRPEAANEFYDGDHDHDKESDVEI
Protein: RNA helicase (EC 3.6.4.13) (E7EWK3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDERREEQIVQLLNSVQAKNDKESEAQISWFAPEDHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHY
Protein: Macrophage migration inhibitory factor (EC 5.3.2.1) (EC 5.3.3.12) (L-dopachrome isomerase) (L-dopachrome tautomerase) (Phenylpyruvate tautomerase) (Q0ZBR7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Aspartate aminotransferase.
- Aspartate aminotransferase
- Aspartate aminotransferase, mitochondrial
- Tyrosine aminotransferase
- 4-hydroxyphenylpyruvate dioxygenase
- aspartate transaminase
- 4-hydroxyphenylpyruvate dioxygenase.
- Amine oxidase
- C-X-C chemokine receptor type 4b
- COP9 signalosome complex subunit 5
Sequence:
MPMFVVNTNVAKDSVPAELLSEATQELAKAMGKPQQYIAVQVVPDQMMMFGGKGDPCALCSLTSIGKISGAQNKQYSKLLMGLLNKHLGVSADRIYINFVDMDPANVAWNNSTFG
Protein: Uncharacterized protein C10orf62 (Q5T681)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLWVQRKRRRKETSECPSDKDKSPESHKAKNESWIKSHFSRLSEEKLALDNNASASGNATQTESGSEEVSSTVHIETFTTRHGEVGSALHRESFTSRQKTSGPSVIQEIHQESGKAPSTDEATWAAVAACTKEIDTQGRHLAHSMLQRAIAYQHSGHLESKDINQEELRALEEVEMKLQKNFLTQRENTIAGANHTHTFYGHSHHSHHGHPSHQSHSLPNRRH
Protein: Translational regulator CsrA (Carbon storage regulator) (Global translational regulatory protein RsmA) (O69078)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00167}.
Interaction partners:
- RNA-binding protein Hfq
- histidine kinase
- RNA polymerase sigma factor RpoS
- Ribosomal RNA small subunit methyltransferase B
- Ribonuclease E
- B-type flagellin
- Polyribonucleotide nucleotidyltransferase
- Response regulator GacA
- Transcription termination factor Rho
- RNA polymerase sigma factor FliA
Sequence:
MLILTRRVGETLMVGDDVTVTVLGVKGNQVRIGVNAPKEVAVHREEIYQRIQKEKDQEPNH
Protein: Rho-related protein racA (EC 3.6.5.2) (Q24814)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states (By similarity). Involved in cytoskeleton remodeling. Plays a role in phagocytosis of bacteria and host erythrocytes. Involved in capping of surface receptors. May be involved in cytokinesis.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P63000}; Lipid-anchor {ECO:0000250|UniProtKB:P63000}; Cytoplasmic side {ECO:0000250|UniProtKB:P63000}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P63000}. Cytoplasm {ECO:0000250|UniProtKB:P63000}.
Interaction partners:
Sequence:
MQAVKCVIVGDGAVGKTCLLISYTTNAFPNEYIPTVFDNYSATVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSVVSPPSFDNVSSKWQPEVSHHCPKTPCLLVGTKLDMREDKEQLKRLEEKKITPITTEQGEAKCKDIGAVKYIECSALTQKNLRLVFDEAVRAVISPAGGAKKDKKNNRGCLLF
Protein: 4Fe-4S ferredoxin FdxA (Ferredoxin) (P00198)
Organism: Gottschalkia acidurici (strain ATCC 7906 / DSM 604 / BCRC 14475 / CIP 104303 / KCTC 5404 / NCIMB 10678 / 9a) (Clostridium acidurici)
Function: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
Interaction partners:
- Iron hydrogenase HydA
- Iron hydrogenase HydB
- Pyruvate:ferredoxin oxidoreductase Por
- Pyruvate:ferredoxin oxidoreductase Por
- Acyl carrier protein
- Iron hydrogenase HydA
- Iron hydrogenase HydA
- Iron hydrogenase HydC
- M16 family peptidase
- Zinc-dependent protease
Sequence:
MAYVINEACISCGACEPECPVNAISSGDDRYVIDADTCIDCGACAGVCPVDAPVQA
Protein: Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome c oxidoreductase core protein 2) (P07257)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:11502169, ECO:0000269|PubMed:18390544, ECO:0000269|PubMed:22984289, ECO:0000269|PubMed:30598554}; Peripheral membrane protein {ECO:0000269|PubMed:18390544, ECO:0000269|PubMed:30598554}; Matrix side {ECO:0000269|PubMed:18390544, ECO:0000269|PubMed:30598554}.
Interaction partners:
- Cytochrome b-c1 complex subunit 7, mitochondrial
- Cytochrome b-c1 complex subunit 6, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome b-c1 complex subunit 9, mitochondrial
- Cytochrome c oxidase subunit 12, mitochondrial
- Cytochrome c oxidase subunit 4, mitochondrial
- Cytochrome c oxidase subunit 5B, mitochondrial
- Cytochrome c oxidase subunit 6, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome c oxidase subunit 2
Sequence:
MLSAARLQFAQGSVRRLTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVLANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL
Protein: Potassium channel subfamily K member 1 (Q5T5E6)
Organism: Homo sapiens (Human)
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004221}. Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00004541}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. Recycling endosome {ECO:0000256|ARBA:ARBA00004172}. Synaptic cell membrane {ECO:0000256|ARBA:ARBA00034109}.
Interaction partners:
Sequence:
VLRVLSPDLVRRLLNLAVRAFQVPKGESLNFPESTPGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLSFSSITDQAAGMKEDQKQNEPFVAT
Protein: Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Q9JJL4)
Organism: Rattus norvegicus (Rat)
Function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Interaction partners:
- Exocyst complex component 7
- Adapter molecule crk
- Intersectin-1
- Crk-like protein
- Golgi-associated PDZ and coiled-coil motif-containing protein
- CDC42 effector protein
- CDC42 effector protein 4
- Intersectin 2
- Cdc42-interacting protein 4
- Actin nucleation-promoting factor WASL
Sequence:
MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPVCVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
Protein: Light-harvesting complex-like protein OHP2, chloroplastic (One-helix protein 2) (Protein LIGHT-HARVESTING LIKE 6) (Q9FEC1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a photoprotective role within PSI in response to light stress. Forms a trimeric complex with OHP1 and HCF244 that is required to promote PSII core subunit assembly. The trimeric complex forms a transient PSII reaction center-like complex with PsbA, PsbD, PsbE, PsbF and PsbI subunits in thylakoids for early assembly of PSII as well as PSII repair. The trimeric complex is required for the recruitment of ribosomes to the psbA mRNA during PSII biogenesis and repair. Forms an heterodimer with OHP1 that binds chlorophylls and carotenoids, and that may function in the delivery of pigments to the PsbA subunit of PSII.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:12805611, ECO:0000269|PubMed:29438089, ECO:0000269|PubMed:30397023}; Single-pass membrane protein {ECO:0000255}. Note=Associates with PSI under low or high light conditions. {ECO:0000269|PubMed:12805611}.
Interaction partners:
- Light-harvesting complex-like protein OHP1, chloroplastic
- Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 244
- Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 173
- Photosystem II stability/assembly factor HCF136
- Photosystem II 22 kDa protein, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 5, chloroplastic
- Protein MAINTENANCE OF PSII UNDER HIGH LIGHT 1
- Early light-induced protein 1
- Chlorophyll a-b binding protein CP26, chloroplastic
- Protein disulfide-isomerase LQY1, chloroplastic
Sequence:
MSVASPIQCIRILNPSSSSSSSTASSSFRFSTTTKPCVFIIRCSQTEGPLRRPSAPPTLREPQKPVPPSQPSSSPPPSPPPQKAVAVDGKSVTTVEFQRQKAKELQEYFKQKKLEAAGQGPFFGFQPKNEISNGRWAMFGFAVGMLTEYATGSDLVDQVKILLSNFGILDLE
Protein: EP300-interacting inhibitor of differentiation 1 (CREBBP/EP300 inhibitory protein 1) (E1A-like inhibitor of differentiation 1) (EID-1) (Q9DCR4)
Organism: Mus musculus (Mouse)
Function: Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
Subcellular location: Nucleus {ECO:0000269|PubMed:11964378}. Cytoplasm {ECO:0000269|PubMed:11964378}. Note=May shuttle between nucleus and cytoplasm. {ECO:0000269|PubMed:11964378}.
Interaction partners:
- Nuclear receptor subfamily 0 group B member 2
- Retinoblastoma-like protein 1
- Necdin
Sequence:
MAEMAELCELYEESNELQMDVLPGEGYMEVGRGARGPAPEEGPMEEEAGPAAARAQRGLFPEAGADLEGDEFDDWEDDYEFPEEERWSGAMHRVSAALEEANKVFLRTARAGDALDGGFQARCEKSPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRELMLTREEETT