wanglab/gogpt-training-data huggingface dataset:
Protein: GDP-fucose transporter 1 (Neuronally altered carbohydrate) (Solute carrier family 35 member C1 homolog) (Q9VHT4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:19948734, ECO:0000269|PubMed:22745127}; Multi-pass membrane protein {ECO:0000269|PubMed:19948734, ECO:0000269|PubMed:22745127}.
Interaction partners:
- Endoplasmic reticulum GDP-fucose transporter
- Alpha-
- UDP-galactose transporter senju
- IP10585p
- GDP-mannose 4,6 dehydratase
- Mannose-P-dolichol utilization defect 1 protein homolog
Sequence:
MYKNLEEHNRLVNKYLKIFFVVSLYWCTSILTVFVNKHLLSSDTVNLGAPLFMSWFQCVVSTVICFVASRLSRKYPSVFTFPEGNPLDIDTFRKILPLSVLYTLMIGANNLSLSYVTVAFYYIGRSLTTVFSVVLTYVILRQRTSFKCLLCCGAIVVGFWLGVDQESLTEVFSWRGTIFGVLSSLALAMFSIQTKKSLGYVNQEVWLLSYYNNLYSTLLFLPLIIINGELESIITYPHLWASWFWAAMTLSGLCGFAIGFVTALEIKVTSALTHNISGTAKACAQTVIATQYYHDVRSALWWTSNVVVLVASAAYTRVKQLEMMRQHQQRSTATQKA
Protein: p44 outer membrane protein, C-terminal (Q2GIY3)
Organism: Anaplasma phagocytophilum (strain HZ)
Interaction partners:
Sequence:
MQIVFRTSLTPKLAYRLKAGLSYQLSPEISAFVGGFYHRVVGDGVYDDLPAQRLVDDTSPADRTKDTAIANFSMAYVGGEFGVRFAFFEVGHLLS
Protein: PDZ domain-containing protein 7 (Q9H5P4)
Organism: Homo sapiens (Human)
Function: In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:20440071}. Nucleus {ECO:0000269|PubMed:20440071}. Cell projection, stereocilium {ECO:0000250|UniProtKB:E9Q9W7}. Note=Localizes at the ankle region of the stereocilia. {ECO:0000250|UniProtKB:E9Q9W7}.
Interaction partners:
- Adhesion G-protein coupled receptor V1
- Usherin
- pre-mRNA splicing regulator USH1G
- Whirlin
- Harmonin
- Vezatin
- Unconventional myosin-VIIa
- F-BAR and double SH3 domains protein 2
- Clarin-1
- Calcium and integrin-binding family member 2
Sequence:
MAQGFAVGFDPLGLGDLSSGSLSSLSSRGHLGSDSGSTATRYLLRKQQRLLNGPPRGIRASSPMGRVILINSPIEANSDESDIIHSVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVKVLTSSSRLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCGSTPSDTSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSCASSAPYSSGSLPSDRMDICLGQEEPGSRGPGWGRADTAMQTEPDAGGRVETWCSVRPTVILRDTAIRSDGPHPGRRLDSALSESPKTALLLALSRPRPPITRSQSYLTLWEEKQQRKKEKSGSPGEKGALQRSKTLMNLFFKGGRQGRLARDGRREAWTLDSGSLAKTYPRLDIEKAGGVGPVQKFVTWRLRRDQERGRALLSARSGSPSSQLPNVDEQVQAWESRRPLIQDLAQRLLTDDEVLAVTRHCSRYVHEGGIEDLVRPLLAILDRPEKLLLLQDIRSVVAPTDLGRFDSMVMLVELEAFEALKSRAVRPPALRPARQDTPPKRHLITPVPDSRGGFYLLPVNGFPEEEDNGELRERLGALKVSPSASAPRHPHKGIPPLQDVPVDAFTPLRIACTPPPQLPPVAPRPLRPNWLLTEPLSREHPPQSQIRGRAQSRSRSRSRSRSRSSRGQGKSPGRRSPSPVPTPAPSMTNGRYHKPRKARPPLPRPLDGEAAKVGAKQGPSESGTEGTAKEAAMKNPSGELKTVTLSKMKQSLGISISGGIESKVQPMVKIEKIFPGGAAFLSGALQAGFELVAVDGENLEQVTHQRAVDTIRRAYRNKAREPMELVVRVPGPSPRPSPSDSSALTDGGLPADHLPAHQPLDAAPVPAHWLPEPPTNPQTPPTDARLLQPTPSPAPSPALQTPDSKPAPSPRIP
Protein: Paired box protein Pax-2 (Q02962)
Organism: Homo sapiens (Human)
Function: Transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
Subcellular location: Nucleus.
Interaction partners:
- PAX-interacting protein 1
- T-cell leukemia homeobox protein 1
- LIM homeobox transcription factor 1-beta
- Protein phosphatase EYA1
- Wilms tumor protein
- Homeobox protein engrailed-1
- Homeobox protein SIX1
- Homeobox protein GBX-2
- Homeobox protein OTX2
- LIM/homeobox protein Lhx1
Sequence:
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
Protein: 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Glycogen-branching enzyme) (P32775)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:38832010}. Note=Localizes to glycogen granules in the cytoplasm. {ECO:0000305|PubMed:38832010}.
Interaction partners:
- Glycogenin-1
- Glycogen [starch] synthase isoform 2
- Glycogen phosphorylase
- Glycogen [starch] synthase isoform 1
- Glycogenin-2
- Glycogen debranching enzyme
- Ornithine carbamoyltransferase
- Phosphoglucomutase 2
- Glucoamylase, intracellular sporulation-specific
- Alpha,alpha-trehalose-phosphate synthase 56 kDa subunit
Sequence:
MYNIPDNVKGAVEFDPWLKPFADVLSERRYLADKWLYDITHATPDGSYQSLSKFARDSYKSYGLHANPETKEITYKEWAPNAERAFLVGDFNNWDTTSHELKNKDEFGNFTITLHPLPNGDFAIPHDSKIKVMFILPDGSKIFRLPAWITRATQPSKETSKQFGPAYEGRFWNPENPYKFVHPRPKFSESVDSLRIYEAHVGISSPEPKITTYKEFTEKVLPRIKYLGYDAIQLMAIMEHAYYASFGYQVTNFFAASSRFGTPEELKELIDTAHSMGILVLLDVVHSHASKNVEDGLNMFDGSDHQYFHSISSGRGEHPLWDSRLFNYGKFEVQRFLLANLAFYVDVYQFDGFRFDGVTSMLYVHHGVGAGGSFSGDYNEYLSRDRSFVDHEALAYLMLANDLVHEMLPNLAVTVAEDVSGYPTLCLPRSIGGTGFDYRLAMALPDMWIKLIKEKKDDEWEMGSIVYTLTNRRYGEKVVAYCESHDQALVGDKTLAFWLMDAAMYTDMTVLKEPSIVIDRGIALHKMIRLITHSLGGEAYLNFEGNEFGHPEWLDFPNVNNGDSYKYARRQFNLADDPLLRYQNLNEFDRSMQLCEKRHKWLNTKQAYVSLKHEGDKMIVFERNNLLFIFNFHPTNSYSDYRVGVEKAGTYHIVLNSDRAEFGGHNRINESSEFFTTDLEWNNRKNFLQVYIPSRVALVLALKE
Protein: E3 ubiquitin-protein ligase (EC 2.3.2.27) (B7Z083)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514, ECO:0000256|RuleBase:RU367115}.
Interaction partners:
Sequence:
MSQQRSTEQIAASNNNTSDVIALDDDEDTDVQFVAALRPTAPVIDLCVSPSTSAAAAAAAAAAAHSGGGSGEDPAVGSASGAAASDTDSLASSPDEGALATGVDAAAAVSGEDSPSAAAAALECPICLQTCIHPARLPCGHIFCFLCVKGVAYKNRRCAMCRREIPAEFLDHPQLVNGIEDICTTRATEDGFQWYYEGRNGGWWAYDSRTNADIEIAYAGFEIFKADNPELAPLFDRDCPNPINHYCLCDENIIFYNADSEIVIYPTIIRSSGQGAPASSENNGRDSPALSLDDIMSLDPDELNIIRPHPCTLPIQICGRMYIIDFLQNLQYLRLTPEKSRNIMRCKSTDDVSGGMRGVAGLSQN
Protein: Nuclear receptor coactivator 4 (A0A8I6A3B1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSSWCYLVFFLSFEGTVSRMNTSLEQSGCCSSRETLLRCSDARRELELAIGGVLRAEQQMKDNLREVKAQIHSCISRHLECLRSREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFNCLIHQLEITQNKDLANQVALCLERLGSLTLKPEDSTVLLFEADASALRQTITTFGSLKTIQIPEHLMAHPSSSSVRPFLEKRGYTQVPEQKSASSGTAVSLSEWLLVSKPAIGPQAPYVPSTNPQDWLTPKQTLENSQTSARICSDAWGNLKGLENWLLNSHQQEIPGKPSSSKCNSHCSTSSFSTEDEKVEDVEVLDQDELDLSDWLVTPQEPRDLEKPVNGRSDTSDKFKLLFQVFREPYNVNDWLVKPDSCTNCQGNQPRGVEIENLGNLKCLNDHLEAKKSLPVPGVITEGWLVQNHQDTCKVEEVCKANEPCTSFAECVCDDSCEKEAMHKWLLKKEGKDKNGMPMGPKSESEKHRESLSLWLCPSRNELTEHAKTPKTTAPARIADSFHIIRNSSLSEWLIGPTCKGGGPKEVPNMEERASKEMLKSPMATYWRPFNTADWVLPGKKVGNLSQFSSGEDKWLLRKKAQEVFLNSPLQEERNFRSDCYGLPAVCDLFACMQLKVDKDKWLYRAPLQM
Protein: Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase) (P10760)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine. Binds copper ions (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P23526}. Melanosome {ECO:0000250|UniProtKB:P23526}. Nucleus {ECO:0000250|UniProtKB:P23526}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P23526}.
Interaction partners:
- Cystathionine beta-synthase
- Methionine synthase
- Betaine--homocysteine S-methyltransferase 1
- S-methylmethionine--homocysteine S-methyltransferase BHMT2
- Cystathionine gamma-lyase
- DNA
- Kynurenine--oxoglutarate transaminase 1
- DNA
- DNA
- S-adenosylhomocysteine hydrolase-like protein 1
Sequence:
MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY
Protein: Ethylene receptor 1 (LeETR1) (EC 2.7.13.3) (Q41342)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- Ethylene-insensitive protein 2
- Green ripe
- non-specific serine/threonine protein kinase
- Green ripe-like 1
- Ethylene insensitive 3-like DNA-binding domain-containing protein
- Green ripe-like 2
- Coronatine-insensitive 1
- 1-aminocyclopropane-1-carboxylate synthase
Sequence:
MGSLLRMNRLLSSIVESCNCIIDPQLPADDLLMKYQYISDFFIALAYFSIPVELIYFVKKSAVFPYRWVLVQFGAFIVLCGATHLINLWTFNMHTRNVAIVMTTPKALTALVSCITALMLVHIIPDLLSVKTRELFLKKKAAQLDREMGIIRTQEETGRHVRMLTHEIRSTLDRHTILKTTLVELGRTLALEECALWMPTRTGLELQLSYTLRHQNPVGLTVPIQLPVINQVFGTNHVVKISPNSPVARLRPAGKYMPGEVVAVRVPLLHLSNFQINDWPELSTKRYALMVLMLPSDSARQWHVHELELVEVVADQVAVALSHAAILEESMRARDLLMEQNVALDLARREAEMAVRARNDFLAVMNHEMRTPMHAIIALSSLLQETDLTPEQRLMVETILKSSNLLATLINDVLDLSRLEDGSLQLDIGTFNLHALFREVHSLIKPIASVKKLFVTLSLSSDLPEYVIGDEKRLMQILLNVVGNAVKFSKEGNVSISAFVAKSDSLRDPRAPEFFAVPSENHFYLRVQIKDTGIGITPQDIPNLFSKFTQSQALATTNSGGTGLGLAICKRFVNLMEGHIWIESEGLGKGSTAIFIIKLGIPGRANESKLPFVTKLPANHTQMSFQGLKVLVMDENGVSRMVTKGLLTHLGCDVTTVGSRDECLRVVTHEHKVVIMDVSMQGIDCYEVAVVIHERFGKRHGRPLIVALTGNTDRVTKENCMRVGMDGVILKPVSVYKMRSVLSELLEHGVVLES
Protein: Y box binding protein 2 (D4A3P0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSEAEAAVVATAAPAATVPATAAGVVAVVVPVPAGEPQKAGGGAGGGGGAASGPAAGTPSAPGPRTPGNQATAASGTPAPPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVKGSRYAPNRRRFRRFIPRPRPAAPPPMVAEAPSGGTEPGSEGERAEDSGQRPRRRRPPPFFYRRRFVRGPRPPNQQQPIEGSDGVEPKETTPLEGDQQQGDERVPPPRFRPRYRRPFRPRPPQQPTTEGGDGETKPSQGPTDGSRPEPQRPRNRPYFQRRRQQPPGPRQPIAAETSAPINSGDPPTTILE
Protein: DUF306 domain-containing protein (Q582E9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKETLLLFLPTFKPTRITMATCPKHLFGKYHLKSFNGKSALEGELAGVTLELGEEDGRVTVRAKAGNAMSGVLKYEGGMLTGPLMSTMMMPPPAVLKVERTLVSGFSSGMHALREGSSLTLSHKTDTMVFEAVE
Protein: Mitotic deacetylase associated SANT domain protein (A0A1C7CYX1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSEKKKKTETFSKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRLKEKEAAAAAAAAHQQALREESGAGDKG
Protein: D-galactonate dehydratase family member Dd703_0947 (EC 4.2.1.-) (D-gluconate dehydratase) (EC 4.2.1.39) (D-mannonate dehydratase) (EC 4.2.1.8) (C6CBG9)
Organism: Musicola paradisiaca (strain Ech703) (Dickeya paradisiaca) (Dickeya dadantii)
Function: Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).
Interaction partners:
- Mannitol dehydrogenase domain protein
- Mannitol dehydrogenase domain protein
- Mandelate racemase/muconate lactonizing protein
- Mannonate dehydratase
- Altronate dehydratase
- Mandelate racemase/muconate lactonizing protein
- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
- 2-dehydro-3-deoxygluconokinase
- PfkB domain protein
- Ribulose-phosphate 3-epimerase
Sequence:
MSKLKITNVKTILTAPGGIDLAVVKVETNEPGLYGLGCATFTQRIFAVKSAIDEYMAPFLIGKDPTRIEDIWQSAAVSGYWRNGPIMNNALSGVDMALWDIKGKLAGMPVYELLGGKCRDGIPLYCHTDGGDEVEVEDNIRARMEEGYQYVRCQMGMYGGAGTDDLKLIATQLARAKNIQPKRSPRSKTPGIYFDPEAYAKSVPRLFEHLRNKLGFGIEFIHDVHERVTPVTAIQLAKTLEPYQLFYLEDPVAPENIDWLRMLRQQSSTPISMGELFVNINEWKPLIDNKLIDYIRCHVSTIGGITPAKKLAVYSELNGVRTAWHGPGDISPVGVCANMHLDMSSPNFGIQEYTPMNDALREVFPGCPEIDQGYAYVNDKPGLGIDINETLAEKYPCDGGIPSWTMARTPDGTASRP
Protein: Centrosomal protein 170 (E7EWM2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
Protein: Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3A) (Smt3A) (P55854)
Organism: Homo sapiens (Human)
Function: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. Plays a role in the regulation of sumoylation status of SETX.
Subcellular location: Cytoplasm. Nucleus. Nucleus, PML body {ECO:0000250}.
Interaction partners:
Sequence:
MSEEKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVPESSLAGHSF
Protein: Pre-mRNA-splicing factor Syf2 (Q9V5Q4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in pre-mRNA splicing as component of the spliceosome.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O95926}.
Interaction partners:
- Pre-mRNA-processing factor 17
- Protein crooked neck
- Pre-mRNA-splicing factor syf1 homolog
- Cell division cycle 5, isoform A
- 116 kDa U5 small nuclear ribonucleoprotein component
- RE31520p
- Pleiotropic regulator 1
- Puff-specific protein Bx42
- Pre-mRNA-processing factor 19
- U5 small nuclear ribonucleoprotein 200 kDa helicase
Sequence:
MEKTKTAAEKLAERKARLLDLHKKRQEARTDNHQEVVAEDARKKLPKNWEARKRQAEWILADDKARAEAQAAGKDYERLKLLEVSAVDADRIEKKKKRKDNPDLGFSTYEAQTARQYNRLVKSMPARDLEKYERQKEELGDAFYGGAHTTLHSRTKDTPGAINKMVTDLEQQIERRKKYSRRRIYNDDADVDFINERNSKFNKKLDRFYSEHTAEIKQNLERGTAI
Protein: Uncharacterized protein T05G5.5 (P34558)
Organism: Caenorhabditis elegans
Interaction partners:
- Cytidyltransferase-like domain-containing protein
- 4'-phosphopantetheine phosphatase
- L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
- L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
- Trifunctional purine biosynthetic protein adenosine-3
- Adenylosuccinate lyase
- Flavoprotein domain-containing protein
- DNA/pantothenate metabolism flavoprotein C-terminal domain-containing protein
- pantothenate kinase
- Ribonucleoside-diphosphate reductase large subunit
Sequence:
MWLDWFFPIEMLVVGLSGGVATGKSTVSSVFRAHGVPIIDADQVARQVVVPGTSTYNRLRKEFGDEYFDDEHGGVLRRDKLGKLIFSNPEKRKALNGITHPAIRWEMFKQFLTLLITGTKYIVFDTPLLFESGYDKWIGTTIVVWCDFEQEVERMVTRDNISRADAESRIHAQMDIEEKKKRAKIVIDNNGNIDELREKVKHVIAQLDKSWKPYIFRVAFGIILGVVPYYFFKYIRS
Protein: Epsin (A0A1D8PGB7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
- Clathrin heavy chain
- Clathrin light chain
- Actin cytoskeleton-regulatory complex protein PAN1
- AP-2 complex subunit alpha
- Ent3p
- Cta3p
- Sla2p
- Apm4p
- ENTH domain-containing protein
- Polyubiquitin
Sequence:
MSKLVRSIKNVAGGYSSAQRVVRNATSNDPTGPTTFDMEEISSFTYQSQTEFMEVMDMLDRRLNDKGKNWRHVAKSLTVLDYLVRYGSDKCVLWAKDNLYIIKTLREFVHFDETNNDQGAIIRVKAKELVSLLRDDERLKQERANAKKNKRYRSYDDDDGDGGDDFDSDRRRRNRDERPRRDEPYDAELQRALELSRITAEEEQNRNREEENDPELEAAIKLSLEEEEMRKQNNNLLDLNDETPPQQPQYYLATGFYQQQPQFYAQQPQSQQFQQYDMFGNPIQNPMDTGLYNQQAYYQQPQQQQQQQQFQPNQFTGFNYGQPQQPQAQPEPLQPLKTGSNNPFAMSSGSDNTNKPPTQSLNSLAEQQQQQQQQQPQFFTQPTTAPLKQQNTSSSRFNETHELNDLLTQGTGLDTFGNTGDTRIPHQHTKTQNFINSSGTGYKQTGNEPIRLSSNATGNPFLNTGIGYQGATQQQVPQQQVPQINPAYTGYGFGNAQPQQHQQYQQQQQSRNGNDGPSLIDI
Protein: 4E-interacting protein (Q38DR9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRTTIRYTRPELLSLAPRPEEFTLSEEVLQKFSIIETECPVQSSSPDGTRHDATGQKSSDSKNGALGPASKRATNSERFAPPSRSWRGSRDQEAFEEGYKYELERNAIKKQALQETMEREKQRSDAAASSKDEGKNDTNKWGPSSPSRTEVKAEVDDEIERLMVSIAPSGEGGKKVAKSRFFSGANSGFQDTNPTSAPLVQAISEPLTSASLNQVKDPWALPSMVPASGNVVWNNVEASKPTGVDAALERKNPSANVGMNSLLTGSLSLGVPSTAPTQHAGAVPTQPSMQPAVLHSVPAAPSVEAGAATSARAPATQPTETSASNQPRTWNAHDLEQRLISEQKVSRQPEVESKPIEATALEQQLLMQVKQSLGRPQTQPQAAVMSQMPGSAVPVTGAPPLLSVSGHMTPPQMSTTQLPAHVPQQQRPQQQPVQMPWGVPVQKVAPQQMQKLVQAPPQPQHRQTGVPQPVPIIVSGAQGAPYYAQPAMPGHYVAGFVPSQAQQPMMFYRPADGTAPYTVGATGFPPGTQVLFAQQQQAKQPNQRR
Protein: DUF724 domain-containing protein 6 (AtDUF6) (O22897)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the polar growth of plant cells via transportation of RNAs.
Subcellular location: Nucleus {ECO:0000269|PubMed:19795213}.
Interaction partners:
- Uncharacterized protein At5g06590
- At3g57000
- AT0ZI1 protein
- Arginine-specific demethylase JMJ22
- Proline-rich extensin-like protein EPR1
- WAT1-related protein At3g45870
- WAT1-related protein At3g18200
- WAT1-related protein At4g30420
- Aladin
- Protein trichome birefringence-like 3
Sequence:
MEETIRKGSEVEVSSTEEGFADAWFRGILQENPTKSGRKKLRVRYLTLLNDDALSPLIENIEPRFIRPVPPENEYNGIVLEEGTVVDADHKDGWWTGVIIKKLENGKFWVYYDSPPDIIEFERNQLRPHLRWSGWKWLRPDIQELDKSMFSSGTMAEVSTIVDKAEVAWFPAMIIKEIEVDGEKKFIVKDCNKHLSFSGDEARTNSTIDSSRVRPTPPPFPVEKYELMDRVEVFRGSVWRQGLVRGVLDHNCYMVCLVVTKEEPVVKHSDLRPCKVWEDGVWQDGPKQTPVIETPSNVMKTKPMRSCSGAKSMTPKRTTKHARRSLNLEKSAETLTKAESRAATGELRSKRANDVINDNTPLVITPQVKPIASVEPVTPSRVRTATPLKQTKADTQGKSSPKKTLEPMRDENGLENSTRQKVLEEKNSEKKGRKRKRQEEHNSDLKETDESCNGQMAEINDTSSICNDVDDQPLAAWINLPTETSIDHSPIVVNNAAIATDVEERQANDTLMILPFAKKSPFWKMYETQEVCKIAPQSPHFSPLFEAKEELREWTAVGMMVSFYGLLEEVKNLQLDVSPSTLGSLSCSFAELEKHGFDVAAPQSRINKMLSLQDERAKKAEERKGLEKKIEAGEIEGHTYEEEMAELELKILELKRQQVVAKEMKEATDKVTSGMKSYAEMINQEIEDLRLEFQSTASAPW
Protein: Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6) (G3V6S8)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:12549914}. Nucleus speckle {ECO:0000250|UniProtKB:Q13247}.
Interaction partners:
- SRSF protein kinase 1
- Transformer-2 protein homolog beta
- Transformer-2 protein homolog alpha
- Serine/arginine-rich splicing factor 1
- Nuclear RNA export factor 1
- Serine/arginine-rich splicing factor 10
- Tip-associated protein
- Tip-associated protein
- Tip-associated protein
- Nuclear RNA export factor 5
Sequence:
MPRVYIGRLSYNVREKDIQRFFSGYGRLLEIDLKNGYGFVEFEDSRDADDAVYELNSKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDKYGKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSHSPLPAPPSKARSMSPPPKRASRSRSRSRSRSRSSSRD
Protein: TLE family member 4, transcriptional corepressor (H7C4P7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
QQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNENEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSLRTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSP
Protein: Attacin-B (Q9V751)
Organism: Drosophila melanogaster (Fruit fly)
Function: Hemolymph antibacterial protein.
Subcellular location: Secreted {ECO:0000269|PubMed:16510152}.
Interaction partners:
- Diptericin B
- Attacin-A
- Actin-5C
- Metchnikowin
- Diptericin A
Sequence:
MQKTSILILALFAIAEAVPTTGPIRVRRQVLGGSLASNPAGGADARLNLSKGIGNPNHNVVGQVFAAGNTQSGPVTTGGTLAYNNAGHGASLTKTHTPGVKDVFQQEAHANLFNNGRHNLDAKVFASQNKLANGFEFQRNGAGLDYSHINGHGASLTHSNFPGIGQQLGLDGRANLWSSPNRATTLDLTGSASKWTSGPFANQKPNFGAGLGLSHHFG
Protein: X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1) (Q9EPQ2)
Organism: Mus musculus (Mouse)
Function: May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:11104772, ECO:0000269|PubMed:12651948, ECO:0000269|PubMed:29100828}. Note=Situated between the axonemal microtubules and the plasma membrane (PubMed:11104772, PubMed:12651948). In the retinal photoreceptor cell layer, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (PubMed:29100828, PubMed:29899041). Colocalizes with RGPR in the photoreceptor connecting cilium (PubMed:11104772, PubMed:12140192, PubMed:12651948). {ECO:0000269|PubMed:11104772, ECO:0000269|PubMed:12140192, ECO:0000269|PubMed:12651948, ECO:0000269|PubMed:29100828, ECO:0000269|PubMed:29899041}.
Interaction partners:
- X-linked retinitis pigmentosa GTPase regulator
- Nephrocystin-4
- Centrosomal protein of 290 kDa
- Spermatogenesis-associated protein 7 homolog
- Nephrocystin-1
- IQ calmodulin-binding motif-containing protein 1
- Aryl-hydrocarbon-interacting protein-like 1
- Whirlin
- Guanylate cyclase D
- Jouberin
Sequence:
MQHLLEYMPEDLPVRDTDSSPLLKGTSGKNVRAQPHLGRMNQKELNCRRLHLHEEPTLVKEPSPKQRDKNRRRRTNVQRSTTTQPDLRTLAVLQEPERRRRPWVSASPSPSAPPRAPVPGRKAHVQRLCPSTAVGSAQPRVHAGRRLPHIAGPNDRRSHTAPPAFKDYVADKNTRIEITREPSQLTHTMTTDSTHVEEIPRSPEKTSKVEKPEQRSSEECTQKAAELRASIKENVELIRLKKLLQERNTSLAATEAQLTRVQEAYEDLLQKNQGILDTAHNAFLSQVNELKAELSEESKKAVSLRTQLGDVSILQITLKEFQVRVEDLEKERKLLSDSYDRLLENMLDSSHQPLDSSHQPHWSTELTGKQLPPQVCPLLDQMGTALEETKVFRQATNKAAQDGKLKFQDTDILYQHEQEEESLQSTATVASSPEELCELAAQPTLLPQTDQRESSEPKAQDENDLSQVLSELQVSHAETTLELEKTRDMLLLQRKINMCYQEELEATLTKADRENRDHEEKLERLNHLLDFKNSRIKQLEGILRSHGLPTSEQLKDVAYGTLPPSLCLEPLAAHRGDDEVDMSLLHPSENLFELHVHQAFLTPAALTQAGDTQPTTFCTYSFYDFETHCTPLSTGPQPLYDFTSQYVVQADYLLLHYLQGTSVRLDLHQAMASEYHVLATGWISLDKVLGTVERVHGLATLAGAGGEDLGVLEYWMRLCLPLKPSLQACNKRKKAQAYLSVSVLGARKVQSNESRSETWAPQNELRVEITRCCGLRSRRLGRQPSPYVMYRFFTFPDHDTIIIPASSNPYFKDQALFPVLVTSDLDQYLRREALSVYVFDDEDPEPGSYLGRAQVPLLPLAQNKSIKGDFNLTDSGEKSNGSIKVQLDWKSHYLAPEGFQMSEAEKPEGEEKEEEGGEEEVKEEEVEEEEEEEEEEEEVKEEKEEEEEEEREEEEEKEEEKEEEEEEDEKEEEEEEEEEEEEEEEDENKDVLEASFTEEWVPFFSQDQIASTEIPIEAGQYPEKRKPPVIAEKKEREHQVASYSRRKHSKKPGVQDKNRMEYLSCNILNGNTQQMHYTEWKFSGLKKAEDGGLKAQDKREEPPSPRSALRQEHPSHPRNAFSLADQESCEQASEVSETQTTDSDDIIVTPQAQTVPKADSEKMCIEIVSLAFCPEADVMSDETIQQVYVEYKFCDLPLSETETPMSLRKPRAGEEIHFHFSKVIDLDPVEHQSRRQFLFAMLHAQDSDEGRFKFTVVSDPLDEEKKECQDIGYAYLELWQIFQSGKDILEQELEIVSPRNQAIQIGRLKVSLQAAAALHGIYKEMTEDLFS