wanglab/gogpt-training-data huggingface dataset:
Protein: Kinesin-like protein KIF28 (Kinesin family member 28) (Kinesin-like protein 6) (F8WLE0)
Organism: Rattus norvegicus (Rat)
Function: Microtubule-dependent motor protein required for mitochondrion morphology and transport of mitochondria in neuronal cells.
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:21693574}; Peripheral membrane protein {ECO:0000269|PubMed:21693574}.
Interaction partners:
- KIF-binding protein
Sequence:
MDCEKMGKLPVPRTDSVRVAVRVRPFSQREKNSGSQCVISMHARSITIRDPKDAELVKTFTFDLAYWSHDGFQKDEDGVLIPSDPTSKFAGQSDVFHDIGRGILDSAWQGYNATLLAYGQTGSGKSYSMIGYGANKGIIPRVCEELFQAIEKQKESLEAQVMFSMLEIYNEQIRDLLSRTKAPGGLRVREDQRLGFFVEGLKWVPCEDSVQIEKLVEQGSKIRMTASTNMNASSSRSHMLIAIRFKQVFLDTALTKQSSINMVDLAGSERQRSSGSEGDRLREGSRVNLSLTNLGNVISALADLAMGKKVLHIPYRDSVLTKLLQSALGGNSRTTLIAALSPADICYEETLSTLRYAERAKKVRNRAVINTCPLVRASRAENALLLGFGGAGAAEHSACFWAEQQLGTWGTWAQLLEQARREWEQQYMALAQEQQMVKILPHLLNVNEDPQLTGVLKFFIHNGSCEVGRAASNAICLQSLGISDKHASFTNMDGKVTVAPHITGKVIVNGVPVSSRTKLQHLDRIILGSNSAFLYIGFPSERGAEDLGRFDYDFFQMERAAAEGVSVDMLGTASPGDDQADPSILAVFQDYIKLMPLVVEANQMSEELKKGLKMELKVKNLASSDSRGCDLQKEVMVKVTKQGTHEVWIWSKAKFINRKFLMEELYQRFLESRDSHVAQEDDPFWDPVEVLHLGSAHVWLQSLAHRMMLEEQVEFLNCEGLEEAVLHIQITPCSPEGWAHGEEDTVIDPLELLGKRIDFQIHIVQCLGVKWLKEDATRGIQLGYKVYDLPNTLYTKPVWQSVNPRVEESVHFAALGVSREFLNYLLTNALVVDLWGLQEGCAHLGVSQPDVLFTGEGYIMVDTKTFSSVKDITSNQVPELYQKLLKLEQETELLRDINRALRGENVYLKAALENAGSAPQGERRYHKPDNPEGATVTAAGEAKQMCAQRASSDSQLARALKVFYGGMSVARGQLLRLRQCRPPEDDQMLRPFVHQQSQMLKDLEDLLESSLQKLKSDVAFIVKKKKEYLLPRGR
Protein: Diptericin B (GEO09473p1) (A1ZBF6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Diptericin A
- Attacin-A
- Attacin-C
- Metchnikowin
- Drosocin antimicrobial peptides
- Nuclear factor NF-kappa-B p110 subunit
- Cecropin-C
- Protein immune deficiency
- Cecropin-B
- Defensin
Sequence:
MHFTASLLFIGLACAFSSAWAYPYPDPREIVNLQPEPLAYAPNFDVPLHRVRRQFQLNGGGGGSPKQGFDLSLNGRAPVWQSPNGRHSFDATGSYAQHLGGPYGNSRPQWGAGGVYTFRF
Protein: Unhealthy ribosome biogenesis protein 2 homolog (Q14146)
Organism: Homo sapiens (Human)
Function: Essential for hematopietic stem cell development through the regulation of p53/TP53 pathway.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:15635413}.
Interaction partners:
- Nucleolar pre-ribosomal-associated protein 1
- ATP-dependent DNA helicase DDX31
- Nucleolar protein 8
Sequence:
MAAVYSGISLKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKLELKEDIVERLWIYIDNILHSRKLQNLLKNGKTINLQISLVKIINERVAEFSLSGSQRNICAVLRCCQGILSTPALAVIYTAKQELMVALLSQLCWSACRQPEGAVVAQLFEVIHLALGHYLLILQQQVNPRRAFGDVTAHLLQPCLVLRHLLSGGTWTQAGQGQLRQVLSRDIRSQIEAMFRGGIFQPELLSSYKEGLLDQQQGDVKTGAMKNLLAPMDTVLNRLVDAGYCAASLHTSVVANSVALLYKLFLDSYFKEGNQLLCFQVLPRLFGCLKISHLQEEQSKALSTSDWTTELLVVEQLLNSVANNNIYNIAADRIRHEEAQFRFYRHVAELLINHAQAPIPAWFRCLKTLISLNHLILEPDLDDLLASAWIDAEVTEFRTKKAQEALIRTVFQTYAKLRQVPRLFEEVLGVICRPAAEALRQPVLASGPSTVLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDADMALKSLSLSLLLHCIMFNMRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWLQKVSDSVLLLSYTWAQVDAMFSLNCSQYHSMSGPLIGVALEISNLPSLLPGVKTQHWKKIEKFTAQFSSLGTYCLEQLYLQKMKRTLMQTSFRSEGAIQSLRCDAAFIIGSGRKSLNQRTTASWDGQVGMVSGLTYPVAHWHLIVSNLTILISYLCPDDVGYLASVLLRTLPMGKAQEVSIDEEAYITLEKISKAFLHSPLFPEMQSLHSAFLTCVTTSCSSILCSGAQRDSGLVSQQLPWLFEKDHMVVGHWENRFAKAGPEGIEPRGEIAQNLLSLVKSDFPIQLEGEQLESILGLLEVISALQLDSLLPPYHVHYFLVLLSMAVTKLGCSCSSSLALKFLTTCYQLLGYLQKGKSARSVFKIMYGSDIFEVVLTSLFRASSRFLIEMDDPAWLEFLQVIGTFLEELMQMLIQMKLSLVLNFRKITAFLSSSKPYTEAASSKQLENQNPQGRQLLLVSLTRLCHVLGPFLKEQKLGQEAPAALSELLQQVVLQTGAVLQLCSVPGARGWRLPSVLISSVSTLLEADLGQHCRDGGADISQGSDRTLLSHVALYQGVYSQILLELPALAGHDQSFQAALQFLTLFFLAPELHPKKDSVFTSMFHSVRRVLADPEIPVQVTQDIEPHLGALFTQMLEVGTTEDLRLVMQCILQGLDVSNMWKADVQAVVSAVTLLRLLLNCPLSGEKASLLWRACPQIVTALTLLNREASQEQPVSLTVVGPVLDVLAALLRQGEEAIGNPHHVSLAFSILLTVPLDHLKPLEYGSVFPRLHNVLFSILQCHPKVMLKAIPSFLNSFNRLVFSVMREGRQKDKGSIDDLPTVLKCARLVERMYSHIAARAEEFAVFSPFMVAQYVLEVQKVTLYPAVKSLLQEGIYLILDLCIEPDVQFLRASLQPGMRDIFKELYNDYLKYHKAKHEGEKRYTA
Protein: G2-specific protein kinase nim-1 (EC 2.7.11.1) (P48479)
Organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function: Protein kinase that plays an important role in mitotic regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MSESDKYELLEKIGHGSFGIIRKVRRKADGMILCRKEISYLKMSQKEREQLHAEFSILSTLRHPNIVGYYHREHLKATQDLHLYMEYCGNGDLGRVIRNLIKNNQYAEESFVWSIFSQLVTALYRCHYGVDPPEVGKTVLGLGSTARPKPPSGGMTILHRDLKPENVFLGEDNSVKLGDFGLSKVMQSHDFASTYVGTPFYMSPEICAAEKYTLKSDIWSLGCIIYELCAREPPFNAKTHYQLVQKIKEGKIAPLPSVYSGELFATIKDCLRVNPDRRPDTATLLNLPIVRLMRKEKEVVEFSRTLRTKEETLNKRIRELDSKLSALETEKSSIRAEIDASLRREWEVKARLEIDRLVAQEIESLQQKFEQEVQARVEAELQRHGRGPMFNSHGQQGSFSSTAATLVSDYNLSSVGSGDGDFPSTTDITDISIAESTDGSDITKKIPRTPFHRAQTYSSAPAESVLGTPMDIEMASPSPITIASLSLSPRRMALTKAPTTNPRMIFGEEPTSTDKSNWEVPRETEMIDSGDESEAEALVPSPKRITKSSKNPFSTVTTRSRPSLNSQQNSNVLPIHGLRSKQTLATRSKTVSGVSSIGQHPLRSAPSAPSLRDRKPSPTRRLSRIPSVTGVGRRLSANNINNSSNGGSDAPSSTVTSNITVRTRGLKRMSSTCDESSFSQQQNNQPQQSLPQAPPLKKIGLMAAKNIRGSSLVELHQARAGGRPISAIISNEAKLRAFKEHATIAASAVDSSSSSSSSSGQSQLPTRPRSQPQPITANFEQQQQQQQSNTNSISSSNSAGSGSATGTGTGAGTKSMPWPVAPVWNREVETEEMPSPFIVKTSKRPASFVRPASNLSQS
Protein: Nitrate transporter 2.2 (Nitrate assimilation related protein 4) (Q39609)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Involved in nitrate transport, but does not seem to be able to mediate transport by its own. Acts as a dual component transporter with NAR2 (system 2). Involved in a high affinity transport specific for nitrate.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MATVEKKYPYALDSEGKAKYVPVWRFTQPHMMAFHLSWICFFMSFVATFAPASLAPVIRDDLFLTKSEVGNAGVSAVCGAIAARLFMGIFVDVVGPRYGAAAAMLMTAPAVFCMALVTDFSTFACVRFFIGLSLCMFVCCQFWCGTMFNVQIVGTANAIAAGWGNMGGGACHFIMPLIYQGIKDGGVPGYQAWRWAFFVPGGIYIVTATLTLLLGIDHPSGKDYRDLKKEGTLKAKGNMWPVIKCGLGNYRSWILALTYGYSFGVELTVDNVIVEYLFDQFGLNLAVAGALGAIFGLMNIFSRATGGMISDLIAKPFGMRGRLWVLWITQTLGGIFCIIMGKVSNSLTATIVIMIIFSIFCQQACGMHFGITPFVSRRAYGVVSGLVGAGGNVGAAITQAIWFSGTATWQINLSRPDSFVWMGVQAVALTVAVMFIWFPMWGSMFTGPREGVEEEDYYLREWSAEEVAQGLHQGSMRFAMESKSQRGYKDKRMLDAVGETASADVAAVKATVA
Protein: Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I) (Q60876)
Organism: Mus musculus (Mouse)
Function: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18515545}. Nucleus {ECO:0000269|PubMed:18515545}. Note=Localization to the nucleus is unaffected by phosphorylation status. {ECO:0000269|PubMed:18515545}.
Interaction partners:
- Eukaryotic translation initiation factor 4E
- Regulatory-associated protein of mTOR
- Serine/threonine-protein kinase mTOR
- Proline-rich AKT1 substrate 1
- Target of rapamycin complex subunit LST8
- Mitogen-activated protein kinase 3
- Eukaryotic translation initiation factor 4E type 1B
- Eukaryotic translation initiation factor 4E type 2
- Mitogen-activated protein kinase 1
- Ribosomal protein S6 kinase beta-1
Sequence:
MSAGSSCSQTPSRAIPTRRVALGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVAKTPPKDLPAIPGVTSPTSDEPPMQASQSQLPSSPEDKRAGGEESQFEMDI
Protein: Uncharacterized protein, isoform C (M9NDR0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Syntaxin-5
- Golgi SNAP receptor complex member 1
Sequence:
MFLLGICFICSLNPLVLNAFPVESQADSKDLSVLNAPLTDPADYPDLTNGLTDAEVQESLKDLTLDDLNSLNKLLDERLGRDEDVDSDASLTTHGRQAMANIRKQDFQSMEVGLDDNCRDEEDSDETKPNLCTKRPTCPTTKRCSRKSTCVPKTTRMCSTKSAYDSCKPKSGGFMDDDLISETTKSPKPKNKKCKKPKDDFECEADDFLCQASRRSRGKESRNTLLDEEYIPGRPLTGNAQLGDELTSALNDQGEPLNDAQMELSNSEFDNNLGLENPDSLEQGQPFDLGKDSKINTEQKHQTNLKNEYSRENLMQDYPKNLKHEPSGQLKEEDQANLDQNYNAKIDQEQSTGLELKSQSTLDQEDQFNLNKEYQPNLDFTNPVNFEQEHQSNFDSEYQNNFQKDHLTNWEKEHLANFDAGQSASLHQGEQQFNRNQKAPNVEGVDRSRQNEPIANEADPLDPNDRHQSSRTSLRKREQTEKQFEEHMPNEDDNKQASIKDELMPLNTDLPKQEHLFDSESFIANNARDPPRYLIQMQDDYIQSENDSGERRLLEDRRESEALNMDKLTEEEPRTMEEFHLDSEYRRKKRENKNTDDSPENSKETYIKMLMDSFPRDQGGRINAHAALRQSNLAHLRIKRS
Protein: ABC-type glutathione-S-conjugate transporter (EC 7.6.2.3) (Q7YZW1)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Vacuole membrane {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004128}.
Interaction partners:
Sequence:
MFPLVRELVCGSDYELLETGWRNNSNIPQVTNCGQHTDFSTIPTLFLVIFSPILFYELYKSRNSYLRSFSAISLRIIFCCLLVVDLTATVIYDFYLLFTKSPLYNAIHFYGDLVQYAGFCLALVLTIACRNRGIITSGVITLYWLLVVVCGVPELRYYITGRLYKEYEIHSCRAALYVFAYVCSALELFLSCFADTPSNGYIGKNSCPEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSFIENLIPEVEGYRRKIKKNPEAAIPKNHPSILIPIFKTYKFTLLAGGCYKLMFDLLQFVAPELLRQLISFIEDKNQPMWIGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNLMSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQMEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACAPFLVAVLTFGLYVLWDPENNVLTPQITFVALALFNILRFPLAVFAMVFSQAVQCSASNTRLKEFFAAEEMSPQTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGAFSEFLEEFLLEESKHKGRSVSFGEDSKEVNELLRDLDQVSPAIRQRIQSQMSQEIEKTDDKNAEIIRNGLHKDEQTAHSSIGKSEEKESLLGAISPKEKTPEPPKQTKTQLIEKEAVETGKVKFEVYMSYFRAIGIKIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDVDGVDTDIPRTMSMFIRTAVSSIEIIAIILWATPLAISLLLPLFIVYFVVLRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNPDGIFYSMAKDANVV
Protein: Cell wall protein PGA62 (Flocculation protein 1) (GPI-anchored protein 62) (Q5AF41)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Cell wall protein necessary for cell wall integrity. Plays only a minor role in hyphal morphogenesis and is not critical to biofilm formation.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:19383685, ECO:0000269|PubMed:19555771}. Membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
Sequence:
MQFSSAVVLSAVAGSALAAYSNSTVTDIQTTVVTITSCEENKCHETEVTTGVTTVTEVDTTYTTYCPLSTTEAPAPSTATDVSTTVVTITSCEEDKCHETAVTTGVTTVTEGTTIYTTYCPLPSTEAPGPAPSTAEESKPAESSPVPTTAAESSPAKTTAAESSPAQETTPKTVAAESSSAETTAPAVSTAEAGAAANAVPVAAGLLALAALF
Protein: Probable fructokinase-2 (EC 2.7.1.4) (Q9LNE3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play an important role in maintaining the flux of carbon towards starch formation.
Interaction partners:
- Glucose-6-phosphate isomerase, cytosolic
- Glucose-6-phosphate isomerase 1, chloroplastic
- Sorbitol dehydrogenase
- Hexokinase-4
- Hexokinase-3
- Hexokinase-like 1 protein
- Hexokinase-1
- Hexokinase-2
- Probable hexokinase-like 2 protein
- alpha-D-xyloside xylohydrolase
Sequence:
MTSSNGDNKGLVVSFGEMLIDFVPTESGVSLSESSGFLKAPGGAPANVAIAVSRLGGRAAFVGKLGDDEFGHMLAGILRKNDVDDQGINFDKGARTALAFVTLRSDGEREFMFYRNPSADMLLRPDELNLELIRSAKVFHYGSISLITEPCRSAHMKAMEVAKEAGALLSYDPNLREPLWPSPEEARKQIMSIWDKADIIKVSDVELEFLTGNKTIDDETAMSLWHPNLKLLLVTLGENGCRYYTKDFHGSVETFHVDAVDTTGAGDSFVGALLNQIVDDQSVLEEEERLRKVLRFANACGAITTTKKGAIPALPTDCEALSFLKIQVE
Protein: Endoglin (A0A1Z2R986)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Important for endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P17813}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MKSICCVLVLCLLLCRRSTASESICELKDVSGNSNDWIVLREKPLGCWTDFQTENGTEVHIINLEDNPSVFTVNLLKANKSVVIFTSSSAQSSHAMLFDNPAVSIYVTNKTSLTFIHPTQKPLQILTAPPAGNVSAVLRWAAETFGGVTSVTNARNPKTITFTGVKGSQNSSRCELMPETPTEKPFIHLELNEPIEALKSCYMKHEGEKLHIINIPDGVTIRHVSVHLLSDCNVVLRGPAGTHWIIKNSLRIGILSNNQIHLQSFPLRPRMAISDNPTDIRQKALSYFSSGFISSYSEIRLNVTNVELWITDYSISSAPTEVEKTTPSPTSPPFPVQMQLFSSPDFTTPIDNNSRVLSDKRVYAEISSQTFREASIRVSSCWVRSTPVTREMPFREEPCFIKDCPKRLSFSFQILQDLPAGSWDLECAVKLCGVKRINNEESCTSETPVKRNVQVKPFTPTTNSCFEFGLSAVLGIAFGGFLIGVLLTGALWFIKIRTGHPVALGMRSTAAELSVLSISGCPCGLTKRQPVPTHPSPSENSSANASIGSTQSTPTSSMA
Protein: Nuclear pore complex-interacting protein family member B6 (E9PJ23)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVKLSIVLTPQFLSHDQSQLTKELQQHVKSVTCPCEYLRKVINSLAVYRHRETDFGVGVRDHPGQHGKTPSPQKLDNLIIIIIGFLRRYTFNILFCTSCLCVSFLKTIFWSRNGHDGSMDVQQRAWRSNRSRQKGLRSICMHTKKRVSSFRGNKIGLKDVITLRRHVETKVRAKIRKRKVTTKINRHDKINGKRKTARKQKMFQRAQELRRRAEDYHKCKIPPSARKPLCNWVRMVAAEHRHSSGLPYWPYLTAETLKNRMGRQPPPPTQQHSITDNSLSLKTPTECLLTPLPPSVDDNIKECPLAPLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNLKTPPLATQEAEVEKPPKPKRWRVDEVEQSPKPKRRRVDEVEQSPKPKRQREAEAQQLPKPKRRRLSKLRTRHCTQAWAIRINP
Protein: (thale cress) hypothetical protein (A0A178WJS6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MTTFNYYLAEHPTIVNFRWSPTQSYASTWSFLFTAVSSYIIAAVTLHLLLLITLSLSNRRRGFSLGPIPALHSLTISIISAVIFVGILLSAAAEIRDTRWLWRRTRTTALQWFLCFPVGTRASGRVFFWSYAFYLSRFLHLFRTFFSVIRRRKLSFFQLINQSSLLCISFLWLEYSQSFQVVAILLTTVSYAVVYGYRFWTEIGLRGACFPFVGNCQAILLGCMTVCHVGVLCIHLVKRGGCNGIGAWLFNSVLNAVITLLYLKFYCKTRSMMTKANHNTT
Protein: Ribosome-associated protein oga1 (Ortholog of G4-associated protein 1) (Ribosome clamping factor oga1) (O42914)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14655046}.
Interaction partners:
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein eL13
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein eS6A
- Small ribosomal subunit protein eS6B
- Large ribosomal subunit protein uL13A
- Small ribosomal subunit protein uS17A
Sequence:
MSVASKNLFDLLGEETPAATTTEKKTAASRDKKRSDSPPVPRELVAQSTTSRKRDPNQPTPRERTVNKKADQPRRRRQAPQGNEAFAREGKEARANNAAHPVDATGAPSNRRNARARRGREFDRHSQTGRVDTKKATERGWGDLVNSAANPDVAENEGNTPSGAQTPAAEEENVKTLDEYLSERKSAAKPVGRTVEKLENATKVEKSAPEELFASLKKSASQKKSAAKESKPKKVLLDIEQTFTARPARGGRPNRAPRRGPSETASKTQQAPPTLSETDFPALA
Protein: Down syndrome cell adhesion molecule 1, isoform X (Q0E9I9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVQQFYESEVNNEYVIRGNAAVLKCSIPSFVADFVQVVSWQDEEGQLYGSLGDQQGTDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIGARAPTFSTDSNSFSYTRSVGQSFALLCQAQAYPVPIMRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMELPQVDQFHFNANGVNGGQAVRVMCMVSSGDLPIDIYWLKDGQPLLRSIYHKIDEYTLILSLRQTTIGDSGNYTCVASNAAGVASRWSILKVKVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Vesicle transport v-SNARE 11 (AtVTI11) (Protein SHOOT GRAVITROPISM 4) (Vesicle soluble NSF attachment protein receptor VTI1a) (AtVTI1a) (Vesicle transport v-SNARE protein VTI1a) (Q9SEL6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as a v-SNARE responsible for targeting AtELP-containing vesicles from the trans-Golgi network (TGN) to the prevacuolar compartment (PVC) and mediates liposome fusion. May be also involved in retrograde traffic to the cis-Golgi (By similarity). Promotes the formation of vacuolar membrane 'bulbs'. Necessary to deliver proteins to the lytic vacuole, but seems not involved in storage proteins transport. Required for amyloplast sedimentation in the endodermis during shoot gravitropism, which are thus acting as statoliths. Expression in the endodermis is essential for the shoot gravitropic response, whereas expression in other tissues may be responsible for the correct stem and leaf shape.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:10397763, ECO:0000269|PubMed:15342965, ECO:0000269|PubMed:15797025}; Single-pass type IV membrane protein {ECO:0000255}. Prevacuolar compartment membrane {ECO:0000269|PubMed:10397763, ECO:0000269|PubMed:15342965, ECO:0000269|PubMed:15797025}; Single-pass type IV membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000269|PubMed:15342965, ECO:0000269|PubMed:15797025, ECO:0000269|PubMed:17151019}; Single-pass type IV membrane protein {ECO:0000255}.
Interaction partners:
- Syntaxin-51
- Vesicle-associated membrane protein 727
- Syntaxin-22
- Syntaxin-21
- Tlg2p-like protein a
- VAMP-like protein YKT62
- Syntaxin-42
- VAMP-like protein YKT61
- Syntaxin-52
- Syntaxin-43
Sequence:
MSDVFDGYERQYCELSASLSKKCSSAISLDGEQKKQKLSEIKSGLENAEVLIRKMDLEARTLPPNLKSSLLVKLREFKSDLNNFKTEVKRITSGQLNAAARDELLEAGMADTKTASADQRARLMMSTERLGRTTDRVKDSRRTMMETEEIGVSILQDLHGQRQSLLRAHETLHGVDDNIGKSKKILTDMTRRMNKNKWTIGAIIIALIAAIFIILYFKLTK
Protein: Protein ENHANCED DOWNY MILDEW 2 (F4K3G5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cellular antisilencing factor and regulator of genome DNA methylation patterns involved in the regulation of chromatin states. Together with SUVH4, monitors repressive epigenetic marks H3K27me1, H3K9me2, and prevents DNA-methylation at CHG sites, affecting especially the expression of transposons and developmentally important genes. Regulates alternative RNA processing such as distal 3' polyadenylation by intronic heterochromatin. Epigenetic reader that binds DNA and contributes to transcriptional transposable element (TE) silencing by modulating levels of the repressive post-translational histone modifications (PHM) H3K9me2. In cv. Columbia, required for RPP7-dependent disease resistance against the Hyaloperonospora arabidopsidis isolate Hiks1, by promoting levels of RPP7 via alternative polyadenylation (APA), resulting from cooption of epigenetic information at the TE insertion locus COPIA-R7. Regulates development processes such as the formation of leaf pavement cells, leaf expansion, fertility and flowering. Prevents FLC accumulation to control flowering. Modulates stomatal development by regulating the methylation-mediated silencing of ERECTA receptor genes (e.g. ER, ERL1 and ERL2) and preventing cell divisions.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:20149132, ECO:0000269|PubMed:21830950}.
Interaction partners:
- Protein EMSY-LIKE 2
- Protein EMSY-LIKE 1
- Protein ANTI-SILENCING 1
- At2g32500
- ASI1-immunoprecipitated protein 1
- Protein EMSY-LIKE 4
- PHD finger protein MALE MEIOCYTE DEATH 1
- Pollen Ole e 1 allergen and extensin family protein
- Serine/threonine-protein kinase WNK8
- Lysine-specific demethylase JMJ25
Sequence:
MTFVDDDEEEDFSVPQSASNYYFEDDDKEPVSFARLPIQWSVEEKVDGSGLGFYLRGRSDNGLLPLHKLVKAWRYDLSNFQPEISVLTKDNIWIKLEEPRKSYGELIRTVLVTLHSIQFLRRNPQASEKALWEKLTRSLRSYDVKPSQNDLVDHIGLIAEAAKRDRNLANSKFILAFLTKKPTKRRLPDEDNAKDDFIVGDEDTYVASDEDELDDEDDDFFESVCAICDNGGEILCCEGSCLRSFHATKKDGEDSLCDSLGFNKMQVEAIQKYFCPNCEHKIHQCFICKNLGSSDNSSGAAEVFQCVSATCGYFYHPHCVTRRLRLGNKEESEALERQIIAGEYTCPLHKCSVCENGEVKTDSNLQFAVCRRCPKSYHRKCLPREISFEDIEDEDILTRAWDGLLHNRVLIYCQEHEIDEELLTPVRDHVKFPFTEEQKVFVKEQRRILESHVGRDKARLKVKDPALQDTCGKASKNSFRSSFPSSKDGFSTKKHGLVSSVPDHSRKRKDIDPSIKHKMVPQKSQKMMEDSREAGKNKLGVKEARDAGKSKISLGERLFSYTQEPNPVKPGRVIPVDSKHNKTDSIASKEPGSEIPTLDNDSQRRLLAVMKKATEEITMGTILKKFKIQSTMSTHSTRNVVDKTITMGKVEGSVQAIRTALKKLEEGGNIEDAKAVCEPEVLSQILKWKDKLKVYLAPFLHGARYTSFGRHFTNPEKLQQIVDRLHWYADDGDMIVDFCCGSNDFSCLMNAKLEETGKKCLYKNYDLFPAKNNFNFERKDWMTVSKDELEPGSKLIMGLNPPFGVNASLANKFITKALEFRPKILILIVPPETERLDKKKSSYVLIWEDKTFLSGNSFYLPGSVNEEDKQLEDWNLVPPPLSLWSRSDFAAKHKKIAEKHCHLSRDVGSSKLKIVEEEANASLHPLGASDGMCDDIPMEKDELEVAECVNKILVSEKIDTVETVARVHQSDHLSRRSQLKKEGKTKDYSGRKLGKSMDSNNVDWKSNDMEEDQGELSRAPESIKVKIPEMTSDWQSPVRSSPDDIYAVCTSISTTTPQRSHEAVEASLPAITRTKSNLGKNIREHGCKVQGTGKPEVSRDRPSSVRTSREDIYTVRPSPENTGQKPFEAFEPSYGASLSHFDDGLAAKYGGFGGGYRMPDPPFLPDQFPLRNGPNEMFDFRGYSDLDRGIGQREYPQQYGGHLDPMLAPPPPPNLMDNAFPLQQRYAPHFDQMNYQRMSSFPPQPPLQPSGHNLLNPHDFPLPPPPPSDFEMSPRGFAPGPNPNYPYMSRSGGWIND
Protein: Peroxin-7 (Q9VSN7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Peroxisome matrix {ECO:0000256|ARBA:ARBA00004253}.
Interaction partners:
- Peroxisomal targeting signal 1 receptor
- Peroxisomal membrane protein PEX13
- Peroxisomal membrane protein PEX14
- Alkylglycerone-phosphate synthase
- RING-type E3 ubiquitin transferase
- Peroxisome assembly protein 12
- Peroxisomal ATPase PEX6
- acetyl-CoA C-acyltransferase
- Peroxin-19
- Peroxisomal membrane protein PEX16
Sequence:
MQTQTHTTTDRHGYSLRFSPFEANYLLLATSQLYGLAGGGSLFLLEQNSNTNSSSTDGQSLGELCRLEWSDGLFDVAWCPYAADIAATASGDGSLQIWCGLDGESASNQLTPKQPLICLQEHKNEVYSLDWGEKWNYHTLLSGSWDCTLKLWDCNRQNSITTFVGHNDLIYGAKFSPLIANLFASVSTDGHLNLWNSLDFAGKPLMSIEAHASEALCCDWSHFDRNVLVTGGSDGLIRGWDLRKMRTHVFELYSGEFAVRRLACSPHSAAVLASANYDFTTRIWNLERGESAQEVNARHTEFVCGLDWNPHRTHQLADCGWDSLANVYTPQCLSGDLVV
Protein: Hairy and enhancer of split 6 (Drosophila) (Hairy-related 13.2) (Transcription cofactor HES-6) (Q6P0J1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAPASRSNTHDEDNYGIKDRKTRKPLVEKKRRARINESLQELRLLLADPDAQVKMENAEVLEMTVKRVESILQNKAKEADSVNREANERFAAGYIQCMHEVHTFVSSCPGIDATIAADLLNHLLECMPLNDEERFQDILSDLISDSNNSGTWPGEAAYATLSPGGTSVANGGSSALSPAPSTTSSDDICSDLDDTDTEHSRISVDAGDQAPVVPTLYTNKSIWRPW