wanglab/gogpt-training-data huggingface dataset:
Protein: Cytochrome c oxidase subunit 3 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide III) (P14852)
Organism: Oryza sativa subsp. indica (Rice)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P00420}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P00420}.
Interaction partners:
Sequence:
MIESQRHSYHLVDPSPWPISGSLGALATTVGGVMYMHSFQGGATLLSLGLIFLLYTMFVWWRDVLRESTLEGHHTKAVQLGPRYGSILFIVSEVMFLFAFFWASSHSSLAPTVEIGGIWPPKGIGVLDPWEIPLLNTPILPSSGAAVTWAHHAILAGKEKRAVYALVATVLLALVSTGFQGMEYYQAPSTISDSIYGSTFFLATGFHGFHVIIGTLFLIVCGIRQYLGHLTKKHHVGFEAAAWYWHFVDVVRLFPFVSIYWWGGI
Protein: Glycoprotein hormones alpha chain (GTH-alpha) (Gonadotropin alpha chain) (Q9YGP3)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Function: Shared alpha chain of heterodimeric glycoprotein hormones. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. Involved in gametogenesis and steroidogenesis.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P37204}.
Interaction partners:
- Gonadotropin subunit beta-2
- Gonadotropin subunit beta-1
- Thyrotropin subunit beta
- Thyrotropin receptor
- Lutropin-choriogonadotropic hormone receptor
- Follicle-stimulating hormone receptor
- Thyrotropin receptor
Sequence:
MILILKYTGATIILLSVLIEIGQLFPNNDFGCEECKLKENNIFSKPGAPVYQCMGCCFSRAYPTPLRSEKTMLVPKNITSEATCCVAKEVKRVIVNDVKLMNHTDCHCSTCYYHKF
Protein: Protein SINE2 (Q9SQR5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in innate immunity against the oomycete pathogen A.arabidopsidis (Hpa).
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:24891605}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein SINE3
- Protein SINE4
- SUN domain-containing protein 2
- Hypthetical protein
- SUN domain-containing protein 1
- TIR domain-containing protein
- Microtubule-associated protein RP/EB family member 1B
- Spindle pole body component
- WPP domain-interacting tail-anchored protein 1
- WPP domain-interacting tail-anchored protein 2
Sequence:
MGRNLGSAFRQELANLDKDPDSHKTAMSNLRSIVKDLDAKVVHVFVAQLSDVKEIGLESGGYTVSLFEDLARAHGVKIAPHIDIIMPAIIRTLSSSEGSLRVQQACSRAVAAMARYGIDPTTPEDKKTNVIHSLCKPLSDSLIDSQHQQHLALGSALCLKSLVDCDNWRSASSEMVNNVCQSLAVALEATSSEAKSHMALVMALSKHNPFTVEAYARLFVKSGLRILDLGVVEGDSQKRLLAIQMLNFLMKNLNPKSISSELELIYQEMEKYQKDQHYVKMAAHETMRQAERLICEADPMFDAENCKPRNSLSGSVKSTSSLREHDGSVYSRQDRSYVNDQDEYDVLFSGVASGRTLVSGSPLVTFGDNNQETGFVIESPRIGDQIQCSGVENGNIESVWFHQRNRSSEFNESVCSRTNRSRSSRRNTKKRQSGDICSKHHRHGFAQDPFTELLDNRQQLLQYSETSSSSSIYDTSGTTTPTNTTEDICEKPKTDLDSEAKLKTVETELDPRLGRSKGVLKLGLSVFSIAVAGFASFMWMYLQDDMMPPHLVPT
Protein: Eyes absent homolog (EC 3.1.3.48) (F8WB53)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSKPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL
Protein: sn-glycerol-3-phosphate import ATP-binding protein UgpC (EC 7.6.2.10) (P10907)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters, which are hydrolyzed to G3P and alcohol during transport. The G3P moiety can be detected in the cytoplasm whereas the corresponding alcohol is usually found in the culture medium. It was proposed by Yang et al that the complex could also transport glycerol-2-phosphate (G2P) in vivo, but it was shown later by Wuttge et al that UgpB does not bind G2P, questioning this transport activity. G2P might be converted in the periplasm to G3P before its transport.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01727, ECO:0000305}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01727, ECO:0000305}.
Interaction partners:
- sn-glycerol-3-phosphate transport system permease protein UgpE
- sn-glycerol-3-phosphate transport system permease protein UgpA
- sn-glycerol-3-phosphate-binding periplasmic protein UgpB
- Maltose/maltodextrin transport system permease protein MalG
- Maltose/maltodextrin transport system permease protein MalF
- Glycerophosphodiester phosphodiesterase, cytoplasmic
- Inner membrane ABC transporter permease protein YcjP
- Spermidine/putrescine transport system permease protein PotC
- Putrescine transport system permease protein PotH
- Probable D,D-dipeptide transport ATP-binding protein DdpD
Sequence:
MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKSTLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLKIRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDEPLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGTPVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIELPLNGGYRQYAGRKMTLGIRPEHIALSSQAEGGVPMVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGSTLWLHLAENQLHLFDGETGQRV
Protein: Replication and transcription activator (Rta) (Immediate-early protein Rta) (Protein R) (P03209)
Organism: Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Function: Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial cells. Up-regulates human DCR3/TNFRSF6B by directly binding to its receptor. Globally induces a proteasome-dependent loss of SUMOylated proteins in the host cell and the loss of promeylocytic leukemia nuclear bodies. Improves the stability of the triplex capsid protein TRX1 by reducing the ubiquitination level of the latter. Mediates evasion of inflammasome activation and antiviral responses (T- and NK cell activation) during EBV early lytic infection.
Subcellular location: Host nucleus {ECO:0000269|PubMed:31948747}. Virion tegument. Note=Localizes to the host nucleus during the viral lytic induction. {ECO:0000269|PubMed:31948747}.
Interaction partners:
Sequence:
MRPKKDGLEDFLRLTPEIKKQLGSLVSDYCNVLNKEFTAGSVEITLRSYKICKAFINEAKAHGREWGGLMATLNICNFWAILRNNRVRRRAENAGNDACSIACPIVMRYVLDHLIVVTDRFFIQAPSNRVMIPATIGTAMYKLLKHSRVRAYTYSKVLGVDRAAIMASGKQVVEHLNRMEKEGLLSSKFKAFCKWVFTYPVLEEMFQTMVSSKTGHLTDDVKDVRALIKTLPRASYSSHAGQRSYVSGVLPACLLSTKSKAVETPILVSGADRMDEELMGNDGGASHTEARYSESGQFHAFTDELESLPSPTMPLKPGAQSADCGDSSSSSSDSGNSDTEQSEREEARAEAPRLRAPKSRRTSRPNRGQTPCPSNAAEPEQPWIAAVHQESDERPIFPHPSKPTFLPPVKRKKGLRDSREGMFLPKPEAGSAISDVFEGREVCQPKRIRPFHPPGSPWANRPLPASLAPTPTGPVHEPVGSLTPAPVPQPLDPAPAVTPEASHLLEDPDEETSQAVKALREMADTVIPQKEEAAICGQMDLSHPPPRGHLDELTTTLESMTEDLNLDSPLTPELNEILDTFLNDECLLHAMHISTGLSIFDTSLF
Protein: Centrocin 1 (EeCentrocin 1) [Cleaved into: Centrocin 1, heavy chain; Centrocin 1, light chain] (A0A144LUY5)
Organism: Echinus esculentus (Sea urchin)
Function: Has antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and against fungi with minimum inhibitory concentration (MIC) between 0.78 uM and 50 uM. Shows little hemolytic activity even at a concentration of 100 uM.
Interaction partners:
Sequence:
MMIKIAVVLCAVMATTMVRAKYVEEQELADLLDLLISEEVSSPDDAVALQGWWRRTVDKVRNAGRKVAGFASKACGALGHSPQEARAKVLEAFPEMKEADLDEEDIGKYCGYAHALNGR
Protein: Guanine nucleotide exchange protein SMCR8 (Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog) (Q3UMB5)
Organism: Mus musculus (Mouse)
Function: Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (By similarity). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ULK1/ATG1 kinase complex and inhibiting its protein kinase activity. As part of the C9orf72-SMCR8 complex, stimulates RAB8A and RAB11A GTPase activity in vitro (By similarity). Acts as a regulator of mTORC1 signaling by promoting phosphorylation of mTORC1 substrates (By similarity). In addition to its activity in the cytoplasm within the C9orf72-SMCR8 complex, SMCR8 also localizes in the nucleus, where it associates with chromatin and negatively regulates expression of suppresses ULK1 and WIPI2 genes (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:27617292}. Nucleus {ECO:0000250|UniProtKB:Q8TEV9}. Presynapse {ECO:0000269|PubMed:31651360}. Postsynapse {ECO:0000269|PubMed:31651360}. Note=Localizes mainly in the cytoplasm. {ECO:0000250|UniProtKB:Q8TEV9}.
Interaction partners:
- WD repeat-containing protein 41
- Guanine nucleotide exchange factor C9orf72 homolog
- Ras-related protein Rab-39B
- Ras-related protein Rab-8A
- Serine/threonine-protein kinase TBK1
- Autophagy-related protein 101
- Serine/threonine-protein kinase ULK1
- Serine/threonine-protein kinase ULK2
- TRAF family member-associated NF-kappa-B activator
- Autophagy-related protein 13
Sequence:
MISAPDVVAFTKEDEYEEEPYNEPALPEEYSVPLFPYASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKMGNRKAFAGELEKKLKDLDYTRTVLHTETEIQKKANDKGFYSSQAIEKANELANVEKSIIEHQDLLRQIRSYPRQKTKIPDLQPGDTEHTQDQADQVSTTSNPEESANADLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLSHIEHMFRGDLCYLLTSQIDRVLRKQQPITNFLFEDFVEVDDRMEKQENVPSQPSQDRLPPKPVEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYTGVEATEARSFDPQENLDYLDMDMKGSISSGESIEVLGTEKSASVLSKSDSQASLTVPLSPHVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEEAYADNEGAIHFQASAGSPEPDETQEGNLENIPSQIDSSCCIGKESEGHLVPLPTPAYTLSDEDSVVSIPPQRYIQKDQGLHVDFGVENTDPSPRDNSCEMFPAYELDPSCLLASRDVSKMSLDNYSDTTSYMGSAASTSSDRIPSAPPAGLSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDETIVRKLVTALSIFVPNYGCYAKPVKHWISSPLHIMDFQKWKLIGLQRVASPANVGTLHTLSRYSRYTSILDLDSKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPAHSEETQEAVASRQTSFLKLNLGLVNEDIRVVQYLAELLKLHYMQESPGTTHPLLRFDYVPSFLYKI
Protein: Transcription factor EB (Q709A9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENP
Protein: Organic anion transporter 7 (OAT7) (Organic anion/short-chain fatty acid exchanger) (Solute carrier family 22 member 9) (Q8IVM8)
Organism: Homo sapiens (Human)
Function: Sodium-independent organic anion transporter, exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones such as estrone 3-sulfate (E1S) and dehydroepiandrosterone sulfate (DHEAS). Can transport the statin pravastatin and may contribute to its disposition into the hepatocytes when the function of OATPs is compromised. It is specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate (propanoate), butyrate (butanoate) and valerate (pentanoate). May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs, in particular butanoate, at the sinusoidal membrane of hepatocytes.
Subcellular location: Basolateral cell membrane {ECO:0000269|PubMed:17393504}; Multi-pass membrane protein {ECO:0000269|PubMed:17393504}. Note=Enriched at the sinusoidal part of the plasma membrane.
Interaction partners:
- Multidrug and toxin extrusion protein 2
- Multidrug and toxin extrusion protein 1
- Solute carrier family 2, facilitated glucose transporter member 9
- ATP-binding cassette sub-family C member 4
- Solute carrier organic anion transporter family member 2B1
- Solute carrier organic anion transporter family member 1A2
Sequence:
MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNERKDPREPKQEDPRVEVTQF
Protein: FXYD domain-containing ion transport regulator 3 (Chloride conductance inducer protein Mat-8) (Mammary tumor 8 kDa protein) (Phospholemman-like) (Sodium/potassium-transporting ATPase subunit FXYD3) (Q61835)
Organism: Mus musculus (Mouse)
Function: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (By similarity). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- FXYD domain-containing ion transport regulator 7
- Sodium/potassium-transporting ATPase subunit gamma
Sequence:
MQEVVLSLLVLLAGLPTLDANDPENKNDPFYYDWYSLRVGGLICAGILCALGIIVLMSGKCKCKFRQKPSHRPGEGPPLITPGSAHNC
Protein: Proteasome subunit alpha type (B5DGU4)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU000551}. Nucleus {ECO:0000256|RuleBase:RU000551}.
Interaction partners:
Sequence:
MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVVVTQKKVPDTLLDSSTVTHLFRITENIGCVMSGMTADGKSQVQRARYEAANWNYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMIVIGVDDECGPQVYKCDPAGYYCGFKATAAGVKQTEATSFLEKKVKKKLDLTFKETVETAITCLSTVLSIDFKPSELEIGVISTEDPKFRILTESEVDTHLVSLAERD
Protein: DNA-binding response regulator (Q883X4)
Organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Interaction partners:
- histidine kinase
- histidine kinase
- Sensor protein
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- Sensor protein
- histidine kinase
Sequence:
MRALIVDDDVAIRELLCDYLTRFNINARGVTDGSQMRQALTDETFDVVVLDLMLPGEDGLSLCRWLRSTSDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELVARIQTILRRVRDERSDQRTTIRFDAWRLNSVLRQLTAADGLVVPLSNAEFRLLRVFLERPHRVLSREQLLDAARGRSIEAFDRSIDLLVSRLRQKLGDDPKNPQLIKTVRGEGYLFDARELG
Protein: Prunin 1 Pru du 6.0101 (Pru1 Pru du 6.0101) (11S globulin) (11S seed storage protein) (Allergen Pru du 6.01) (Amandin Pru du 6.0101) (allergen Pru du 6.0101) [Cleaved into: Prunin 1 Pru du 6.0101 acidic chain; Prunin 1 Pru du 6.0101 basic chain] (E3SH28)
Organism: Prunus dulcis (Almond) (Amygdalus dulcis)
Function: Seed storage protein.
Interaction partners:
Sequence:
MAKAFVFSLCLLLVFNGCLAARQSQLSPQNQCQLNQLQAREPDNRIQAEAGQIETWNFNQEDFQCAGVAASRITIQRNGLHLPSYSNAPQLIYIVQGRGVLGAVFSGCPETFEESQQSSQQGRQQEQEQERQQQQQGEQGRQQGQQEQQQERQGRQQGRQQQEEGRQQEQQQGQQGRPQQQQQFRQFDRHQKTRRIREGDVVAIPAGVAYWSYNDGDQELVAVNLFHVSSDHNQLDQNPRKFYLAGNPENEFNQQGQSQPRQQGEQGRPGQHQQPFGRPRQQEQQGSGNNVFSGFNTQLLAQALNVNEETARNLQGQNDNRNQIIRVRGNLDFVQPPRGRQEREHEERQQEQLQQERQQQGGQLMANGLEETFCSLRLKENIGNPERADIFSPRAGRISTLNSHNLPILRFLRLSAERGFFYRNGIYSPHWNVNAHSVVYVIRGNARVQVVNENGDAILDQEVQQGQLFIVPQNHGVIQQAGNQGFEYFAFKTEENAFINTLAGRTSFLRALPDEVLANAYQISREQARQLKYNRQETIALSSSQQRRAVV
Protein: High affinity immunoglobulin epsilon receptor subunit beta (FcERI) (Fc epsilon receptor I beta-chain) (IgE Fc receptor subunit beta) (Membrane-spanning 4-domains subfamily A member 2) (P20490)
Organism: Mus musculus (Mouse)
Function: High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- High affinity immunoglobulin epsilon receptor subunit alpha
- High affinity immunoglobulin epsilon receptor subunit gamma
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase Fyn
- Mast cell carboxypeptidase A
- Low affinity immunoglobulin gamma Fc region receptor III-A
- Paired-Ig-like receptor A2
- T-cell surface glycoprotein CD3 zeta chain
- Ig lambda-2 chain C region
Sequence:
MDTENRSRADLALPNPQESSSAPDIELLEASPAKAAPPKQTWRTFLKKELEFLGATQILVGLICLCFGTIVCSVLYVSDFDEEVLLLYKLGYPFWGAVLFVLSGFLSIISERKNTLYLVRGSLGANIVSSIAAGTGIAMLILNLTNNFAYMNNCKNVTEDDGCFVASFTTELVLMMLFLTILAFCSAVLFTIYRIGQELESKKVPDDRLYEELNVYSPIYSELEDKGETSSPVDS
Protein: Uncharacterized protein YniB (P76208)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENKEGINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQDSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYILPVICIAAGYVFFSLLGFI
Protein: Secretion regulating guanine nucleotide exchange factor (H0YE53)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIVSLQGKYYYPSFADVEMELQRN
Protein: Entomoglyceroporin 2, isoform A (FI07625p) (Q9W1M3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MATTASQSNCWLLQRRQLDSITTVLAEMIATAMLMFLGCMGSVENSVFTNSDFQSALNFGFVVLICIQCFGCVCGAHLNPAVTLATYVYNMISLPMALAYFVAQMVGAFIGYGLLKAVLPESAIYSAENPNGVCLTSLNSTLTPWQGLAVEFLITCVLISVCCGVWDPRNATKQDSLPVRFGLAIACLSLTAGQLTGASMNPVRSFAPAIWNGFWDDHWIYWVGPMAAALITSVIYKHAFRRELEESEVDETTMSTKRTSEAELA
Protein: Myoblast determination protein 1 homolog (Myogenic factor 1) (Q90477)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
Subcellular location: Nucleus.
Interaction partners:
- Paired box 7a
- Paired box 3a
- Myocyte enhancer factor 2ca
- Growth/differentiation factor 8
- Transcription factor 12
- Myocyte enhancer factor 2d.
- Myocyte enhancer factor 2aa
- T-box transcription factor T-A
- Transcription initiation factor TFIID subunit 3
- E3 SUMO-protein ligase EGR2a isoform 1
Sequence:
MELSDIPFPIPSADDFYDDPCFNTNDMHFFEDLDPRLVHVSLLKPDEHHHIEDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNDAFETLKRCTSTNPNQRLPKVEILRNAISYIESLQALLRSQEDNYYPVLEHYSGDSDASSPRSNCSDGMMDFMGPTCQTRRRNSYDSSYFNDTPNADARNNKNSVVSSLDCLSSIVERISTETPACPVLSVPEGHEESPCSPHEGSVLSDTGTTAPSPTSCPQQQAQETIYQVL
Protein: Blown fuse, isoform A (Blown fuse, isoform D) (A1Z714)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Elongin-C
- Cullin-2
- Protein similar
- Elongin-B
- RING-box protein 1B
- RING-box protein 1A
Sequence:
MNPKPTTTKLAEIEQFLLDVRAHFRASLETSEYENTSNLFHVTAAEQTAALLARCEILLAAASSASGSGSGLELGSGLGCADEQAAANHRSSLVDCVDSKVGAETGPSGYLEMLASPSPSKSSLSASREYIDLGSSGSLDRCSVNQPVPAAKDKEPHQQLYEICQGQGAGQDEDEAQQAITFTHEVFIDCPYADLPAGHLSLQRSTKYGQLQRIVPKRLFFDQTRKCYCGILNDWMLCYADGPTACRPSSTLYLKSSSIEIEHFGEGKRRDICFQITTDDPNKKFVYQANNEVDAKEWIHAIEAAIRGDAGAHSALKTPPPRKLPTPPVQKKSTYTAADIIYEEPSPVYGLIDSSSMVLPKLPEKSNSPSALARRFEYDVPKCPAQPLQDTSSRVASVSGELESLGLLNEGDIKVQPQPSSLHGSISLDFQARVKTVHSELSTQLSAAGPSPDRLKKAAKKSYSNGSEPEMLSPLTSPVQTPTKDQKKQRKSTTSPQSSPVSKDCDKLARNWFLSRLNKSTGLKATNTGSASPTNAKCKQSEKENLLTEAELGEGYDASPGDRYHGLPGSPPTSPCLKAEAKSKVNMIINQFESSGHLSTMFSVEALAANALASLTSFCESDGCNNYEPIMPLATTPSSFLKKV
Protein: Diaminopimelate epimerase (DAP epimerase) (EC 5.1.1.7) (PLP-independent amino acid racemase) (P0A6K1)
Organism: Escherichia coli (strain K12)
Function: Involved in the succinylase branch of the L-lysine biosynthesis and in the biosynthesis of the pentapeptide incorporated in the peptidoglycan moiety. Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Diaminopimelate decarboxylase
- Succinyl-diaminopimelate desuccinylase
- RNA pyrophosphohydrolase
- UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
- 4-hydroxy-tetrahydrodipicolinate reductase
- Uncharacterized protein YigA
- Tyrosine recombinase XerC
- 4-hydroxy-tetrahydrodipicolinate synthase
- Carbamoyl phosphate synthase large chain
- 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Sequence:
MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
Protein: Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 8 (AthCYSTM8) (Q8W472)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in resistance to abiotic stress.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000269|PubMed:29272523}.
Interaction partners:
Sequence:
MNQSAQNYFSVQKPSETSSGPYTSPPPIGYPTRDAVVGDPPAAAVETNSKGVNPEGCCAAICCCCVLDACF
Protein: Probable histone H2A.5 (HTA7) (Q94F49)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
Interaction partners:
- Histone H4
- Lysine-specific demethylase ELF6
- Histone H2B.9
- Histone H2B.5
- Zinc ion binding / DNA binding protein
- PHD finger family protein / SWIB complex BAF60b domain-containing protein / GYF domain-containing protein
- Histone H2B.6
- Histone H2B.10
- Histone H2B.4
- Histone H2B.1
Sequence:
MESSQATTKPTRGAGGRKGGDRKKSVSKSVKAGLQFPVGRIARYLKKGRYALRYGSGAPVYLAAVLEYLAAEVLELAGNAARDNKKNRINPRHLCLAIRNDEELGRLLHGVTIASGGVLPNINPVLLPKKSTASSSQAEKASATKSPKKA