wanglab/gogpt-training-data huggingface dataset:
Protein: NADH dehydrogenase (Ubiquinone) complex I, assembly factor 6 (A0A1D8PJ15)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}.
Interaction partners:
- SAP domain-containing protein
- Methyltransferase type 11 domain-containing protein
- 3-keto-steroid reductase ERG27
- Ergosterol biosynthetic protein 28
- Farnesyl pyrophosphate synthase
- Glyceraldehyde-3-phosphate dehydrogenase
- TATA-box-binding protein
- Protein arginine methyltransferase NDUFAF7
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH-ubiquinone oxidoreductase chain 1
Sequence:
MITRSRHISKRLYSTNYSAILFNAQENVNQLLESQDRSSYILAQYIPEPVRNTYLAIRAFNLEINKINEGGSNVQSRAARASSQMSNTLGVSTADLKFKFWSDLILRVFTEDSRNETDLGEPIAILLRDGLKHDFNLNISYFQQFLQTRRHFIKNNSSFQTVNDICSYGEGTFSQLNYLTQGLLLSPSISPSVIRLLEYSTELQSQMSDIAAHIGQATAVSSMILGVPFYAQSRNQITLPVDLMTSSGLSQESLLRLFQGHIKDSAEENQIKEALKNVVYETAITANDHMLTAKSKLEMARQEIKKIVQEQPQDQLLNKFSKKWRKGIPDSLYVPTMAGIPTSLFLNKLEKCNFDLFHGRLQKEWRLPMKSFYYYYMRLM
Protein: Ankyrin repeat-containing protein kinase A (EC 2.7.11.1) (Ankyrin repeat-containing protein kinase 1) (Q54HC6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in the development of the fruiting body. Overexpression phenocopies the spnA null phenotype.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14597204}. Membrane {ECO:0000269|PubMed:14597204}. Nucleus {ECO:0000269|PubMed:14597204}. Note=Localized in the subcortical region of the cell with some enrichment in cell protrusions. In developed cells, colocalized with spnA. May translocate to the nucleus in response to a regulatory signal.
Interaction partners:
Sequence:
MSIKLPLSNINSGGNSNNSSSSNSTSNNNININIGNGIPTNIEKMTFEDSETQKLNIKQQSNNNTSTSVCVSSIHSSSPISSPTSHQVNKSSGSLPPVIKRSPTTTHHHNSSGSNSSSSSSGSNNNNNQIKTSNGMNKPNPTGFLFGSKPRENSQNKIDDNKGVNLAVSTSNSSNNFHKSHSESNIININAPPVETVNMEEIYNNIPSSISMENIRENENNNNSSNNNSNNNNNNNNNNNNSNNINNVNGNKSSLASSTSSISSLSSVSTLSTSNAATNTNTNANTTSTTKTTSTVRSTSPTQFKPRVEFDENNPNAIILSRQRCKSISSPSDFRLNPPSNVHMPTSSLSTSTSTTNVNGLLLPNGVGGVSMSFTPSGLPMTPPTNSSQVDTLQMSTESITIQPSSLDSSSESVSDGLQSVSGSPVTASPSPTISNNTNATTTNNNNNTNTNNNNNNNNNQHNHHHHQHSHSQQHDVYQIKKENFPSSPTSPTLLPSETHDFSSEYSSNPGGKCAICRKPLWSFPISDKSRRCRDCSLVVHRACVPLATECPSAKKSPSKLSVPNGNQSNSSSSSSSSSSSSSSSNSSSSNTKGHSRTPSSPSVSSIPGFQLTSNASQNLHVNSHTLSLLVNGATIDSNHYKRNKKSLEAGARDFHFIFRGCGIPLDEFPLDSYVCGLYSYFAHGRLYLTESYVCFYDGFVFDRTKERTKIIKVSNIASIEKRSSGLNPSAIKIKTFDDQSFIFTHFMHREVAFDDLEGLLIHQESLHFAHSIVANNFPGMNEAIRGQTKRLLSRARLDGHYQIHSKIRCPMPSKEILLMSAIKNNNLDMVVTLLNYYCQVNSDEINSVDSKGYTPLHNAVFSECSDQIFMHLLNQKEVRVRERNMDGNTPLHYFCQKFKSPECQRIVQAMIEKGANINEQNYNGETPLHKAIFNHSVRLLMVYILLKNNANVNIVNNAGESPLHYAVRLGRLDVAKMLLAAGADPTIISLRDRKTALALAVDYDVCPEISDLLRRLDTITTSLEMYELEKFQASLVVEELQKENVVARLDEKLLDKIGCTDKEERRKFLSLKSNRLLIHHPARTQGAKIILKEMETMDIKNGKLIISETELEYTEKIGSGASGKVFKGIYRGRVVAIKVLKSADDEMTREDFLKEFGVLASLESHTIVGLYGVVLEPKICLVMEYCSNGSIYHSIRKNPPSWERFFSFVQQMLAGINALHQSTPQVLHRDIKTLNFLVNHNNKVKVADFGLSRFNTESNQETLNKTRGTSVYCAPEVFEGKEYNERSDMYSMGIVMWEIVYCVVYGCYMIPYQEYNKMFNAFQVALLVNSSKRVLRPTIPIGVPQVLKDLIYCLWDHDVSSRPTATEAMTALAVCEKEYKQNKAQWELVITKKEPTPLPRVAPLPAFPGYRQFYEQNLDIKPIPEEEQIYQEAMEKQRRNQEASANRNQKNKELLNNNN
Protein: Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2) (Q8N370)
Organism: Homo sapiens (Human)
Function: Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine. The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent.
Subcellular location: Cell membrane {ECO:0000269|PubMed:30379325}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8CGA3}. Note=Located at the basolateral membrane in the small intestine enterocytes, kidney proximal tubule, thick ascending limb and, to a minor extent, of distal convoluted tubule epithelial cells. {ECO:0000250|UniProtKB:Q8CGA3}.
Interaction partners:
- Large neutral amino acids transporter small subunit 2
- Y+L amino acid transporter 2
- Large neutral amino acids transporter small subunit 1
- Amino acid transporter heavy chain SLC3A2
Sequence:
MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNLAFTVGSFLLSAITLPLGIVMDKYGPRKLRLLGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTLPNMFGDLRSTFIALMIGSYASSAVTFPGIKLIYDAGVSFIVVLVVWAGCSGLVFLNCFFNWPLEPFPGPEDMDYSVKIKFSWLGFDHKITGKQFYKQVTTVGRRLSVGSSMRSAKEQVALQEGHKLCLSTVDLEVKCQPDAAVAPSFMHSVFSPILLLSLVTMCVTQLRLIFYMGAMNNILKFLVSGDQKTVGLYTSIFGVLQLLCLLTAPVIGYIMDWRLKECEDASEEPEEKDANQGEKKKKKRDRQIQKITNAMRAFAFTNLLLVGFGVTCLIPNLPLQILSFILHTIVRGFIHSAVGGLYAAVYPSTQFGSLTGLQSLISALFALLQQPLFLAMMGPLQGDPLWVNVGLLLLSLLGFCLPLYLICYRRQLERQLQQRQEDDKLFLKINGSSNQEAFV
Protein: Forkhead box protein I3-B (Q7T1C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000250|UniProtKB:A8MTJ6}.
Interaction partners:
Sequence:
MTSYESQGQSPTRCGPQFLSLGQEPPELSLYSDSYYPPPSLPSPQRTNPSSYELGDYAASSPNPYLWFNSPGMNSAPYLGGTPGPAGPSFVPQHYGMQRPYLGPGPPGGPGGELSWFSMPSQEDLMKLVRPPYSYSALIAMAIHGAPERRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDSLPEKSSSGGNESGDSNGRGSPKSQSIDISTSPEKGPSPASTGPSPCLSNFLTEMSGVAAGSLDMEADPLSRPFTLSLPVDGAQRASQTTGFSTFTPSTTVSDWASPLPPPPPMSSSPSHSTLAYSGPVLSQFNGHFFPGLSSTGILYPREGTEV
Protein: Uncharacterized membrane protein YDL218W (Q07629)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Uncharacterized vacuolar membrane protein YNR061C
Sequence:
MKRVTGVFLTLLRFSQFASSVLVMSLLAYAIHAYGNRGNKKTNFTLATGVISVFYLIALGILCLALPTLIYIGMYFCAELIVCMLWLAAFVVLAKAQGERSCSNTNADGLYYNPYSGQYTADSHRRACNSSQAAIAFSGLCFVLFLISVILLGINVLTPIRKRYQTQGMWRSGASMGTKLHRWSGLALSEPFEETAAYDNTNVRTGDVEAGAGDNAAYTSEPNGDARYATNDPNGQYHTTTTNTRYTTTTADPKTRYTTNDRNPGSANVANSAVDQHAYSTDESGDRSYQEKVTEGAHSGAMSGSTAEPNRNVNQMP
Protein: Lysophospholipid acyltransferase (A0A1D8PHX1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- Lysophosphatidic acid acyltransferase
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- Phosphatidylserine decarboxylase proenzyme 2
- Bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
- Bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
- Phosphatidate cytidylyltransferase
- diacylglycerol cholinephosphotransferase
- Phospholipase
Sequence:
MISIIQNGISQLSSVSGLDEANLKILICTLLSFPFGIIFKRLPDHDYTLKNIYNVAVSCFYVFGICDLRFGISTLLISATGSYFITRYVRTKSMPWINFLFLMIHMAYSHFHLQFFKEYDPKSIDITGAQMILVMKLSAFGWNIHDGKQPRSTLNDFNKARAITKHPNVLPYIGYVFFYASLLTGPAFDYADYDKFIHGTLFDDVPQDKRPGKNKRRIPRSGVQAFKKFSLGFFWAFLLLQSDKFVTMEYMFSPEFVQYHGLFYRIIYMWILGFTFRLKYYTIWTIAEGACILCGIGYNGVDPETGEFKWNRVQNIDPWSFETGQNVHACLEAWNQNTNIWLKNYVYLRVAKPGKKPGFKSTIFTFTTSAFWHGTRPGYYLTFVVGALMQTVGKYYRRNFRPIFLEADGKTPKPTKIVYDFVCWVNTQLAFGFFVQPFVILGFTKSLECWATVYYWLLWVIAISFFAFSGPFAKSVSKFFKSLQPSYREQQRKSREDKYKLNNEEASIVEQAVGAKLGQDYDIPALGLPPFDVFTDFDQTEVDHDIQHLRKAWTSFRGRRGSITENDFDGLKDAYNNFTNEINDIFNTKKEEFKKEKLNKQN
Protein: DH domain-containing protein (Q57UM7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Telomerase-associated protein, putative
Sequence:
MLSMRYDDGFMNLENGSRHPSSNCNTPSVRFHNGLAWVENWQLSSSNLVPQTPPSAAIGPSRSPSSFSLMKYSHDPYGVRGNSQPQMQQRAAGCMMVGRGPSPNGCSSPVMRLSCVEDGSSRFAPGHSAVVPSAIERPLSQTGQREFPDGRPRRKGRARDRTRGGRSLADVPPPTSMRYFPPPPPCLESMISCGISQATLVKIATRWYERTIACEQSYVGRLHGGCAVLHGAAAFRRQPILGSLQPVLCPRMELTLQFTFDQWLKAASRWWETVIRPMTMEYRLPPPYVF
Protein: Copine 3 (A0A087WYQ3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMT
Protein: 5-(hydroxymethyl)furfural oxidase (EC 1.1.3.47) (5-hydroxymethylfurfural oxidase) (HMFO) (Thiol oxidase) (EC 1.8.3.-) (E4QP00)
Organism: Methylovorus sp. (strain MP688)
Function: Involved in the degradation and detoxification of 5-(hydroxymethyl)furfural (HMF) by mediating its oxidation to furan-2,5-dicarboxylate (FDCA), a biobased platform chemical for the production of polymers. Active with a wide range of aromatic and aliphatic primary alcohols and aldehydes: acts on alcohol groups and requires the spontaneous hydration of aldehyde groups for their oxidation. To a lesser extent, is also able to catalyze the oxidation of thiols that are structurally similar to its alcohol substrates, yielding the corresponding thiocarbonyls.
Interaction partners:
Sequence:
MTDTIFDYVIVGGGTAGSVLANRLSARPENRVLLIEAGIDTPENNIPPEIHDGLRPWLPRLSGDKFFWPNLTIHRAAEHPGITREPQFYEQGRLLGGGSSVNMVVSNRGLPRDYDEWQALGADGWDWQGVLPYFIKTERDADYGDDPLHGNAGPIPIGRVDSRHWSDFTVAATQALEAAGLPNIHDQNARFDDGYFPPAFTLKGEERFSAARGYLDASVRVRPNLSLWTESRVLKLLTTGNAITGVSVLRGRETLQVQAREVILTAGALQSPAILLRTGIGPAADLHALGIPVLADRPGVGRNLWEHSSIGVVAPLTEQARADASTGKAGSRHQLGIRASSGVDPATPSDLFLHIGADPVSGLASAVFWVNKPSSTGWLKLKDADPFSYPDVDFNLLSDPRDLGRLKAGLRLITHYFAAPSLAKYGLALALSRFAAPQPGGPLLNDLLQDEAALERYLRTNVGGVWHASGTARIGRADDSQAVVDKAGRVYGVTGLRVADASIMPTVPTANTNLPTLMLAEKIADAILTQA
Protein: Phospholipase D beta 2 (AtPLDbeta2) (PLD beta 2) (EC 3.1.4.4) (PLDdelta1) (O23078)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine or N-acylphosphatidylethanolamine as substrates.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q38882}. Membrane {ECO:0000250|UniProtKB:Q38882}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q38882}.
Interaction partners:
- CDP-diacylglycerol--serine O-phosphatidyltransferase 1
- Non-specific phospholipase C6
- Non-specific phospholipase C1
- Non-specific phospholipase C2
- Phosphatidyl-N-methylethanolamine N-methyltransferase
- Non-specific phospholipase C4
- Non-specific phospholipase C5
- Phosphatidylserine decarboxylase proenzyme 2
- Phosphatidylserine decarboxylase proenzyme 3
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
Sequence:
MENYGWNYPYYPYRPPRPNPPYPAPPHHHGSMSHSGPLDHHHPPMSYYASFDYQHQPPPPYPPVSYYASFSSHSDLSYSGRLDSSGHGFTSTASPHSPGMHIVPFGKASLKVLLLHGNLDIWVSCANNLPNLDLFHKTLGVVFGGMTNMIEGQLSKKITSDPYVSISVAGAVIGRTYVISNSENPVWQQHFYVPVAHHAAEVHFVVKDSDAVGSQLIGIVTIPVEQIYSGARIEGTYSIRDSNGKPCKPGATLSLSIQYTSMNKLSVYHSGVGAGPYYQGVPGTYFPLREGGSVTLYQDAHVPEGMLPGIKLGNGMCYEHGKCWHDMFHAICQARRLIYITGWSVWHNVRLVRDKEDPSSECRLGELLRSKSQEGVRVLLLVWDDPTSQNILGYMTDGVMGTHDEETRRFFKDSSVQVLLCPRNAGKRHSWVKQREVGTIYTHHQKNLIVDADAGGNRRKIVAFVGGLDLCDGRYDTPQHPLFRTLQTDHNGDYHNPTFTGNVSGCPREPWHDLHSKIDGPAAYDVLTNFEERWLKAAKPHRINKLKTSYDDALLRIDRIPDILRVLDAPTVSANDPEAWHVQIFRSIDSNSVKGFPKDPKYATSKNLVCGKNVLIDMSIHTAYVKAIRAAQHFIYIENQYFIGSSYDWNAHKDIGANNLIPMEIALKIADKIRAKERFAAYIVIPMWPEGVPTGAATQRILYWQHKTMQMMYGTIYNALVEAGLEDEYSPQDYLNFFCLGNREMVNGNNESGTGSASNENTPQGLCRKSRRFMIYVHSKGMVVDDEYVVIGSANINQRSMEGTRDTEIAMGAYQPQHTWARRQSGPRGQIYGYRMSLWAEHMALLDDCFVEPESLGCVRKVRTVAEENWEQFRSEEVSEMRGHLMKYPVEVDRKGKVRPLPGSEEFPDVGGNVVGSFLAIQENLTI
Protein: Microspherule protein 1 (Q6P0E3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- KAT8 regulatory NSL complex subunit 3
- Si:ch211-9d9.1.
- Si:ch211-262i1.5
- KAT8 regulatory NSL complex subunit 2
- INO80 complex subunit C
- INO80 complex ATPase subunit.
- Actin-related protein 8
- TCF3
- Actin-related protein 5
- RuvB-like 1
Sequence:
MEKDVKAVVPSAVGAGSSVGPMVSQSRSEDEQSAAVKRSAAQAFSGAGLIPKRRSSSRSIKRKKFDDELVESSLAKSTTRVKGQPVIEPIRCPGSDLMSSDKKKGLKSASSLTPPLTMVIAPSSMTKRMKKNKQPLQITKDLGRWKPTDDLLLINAVLQTTDLTSVHLGVKFSCRFTLREIQERWYALLYDPVISKLAWQAMRQLHPEAIAAIQSKALFSQAEEALLAKITSNSQPKLDVFQDLLNKHPNVFYPSRTAKNLLVHWQLLKQYYLLEDQSVQPLPKGEQVLNFSDAEQVVDDAKLKDSRDEVLEHELMIADRHQKREIRQLEQELPRWQVLVDSITGMNSPDFDNQTLAALRGRMVRYLMRSREITLGRATKDKQIDVDLSLEGPAWKISRKQGIIKLKNNGDFFIANEGRRPIYIDGRPVLSGNKWKLNNNSVMEIAGLRFVFLINQELISLIKAEAAKMNQP
Protein: 23S rRNA (uridine(2479)-2'-O)-methyltransferase (EC 2.1.1.208) (Avilamycin resistance protein B) (Q9F5K6)
Organism: Streptomyces viridochromogenes
Function: Specifically methylates the 2'-O-ribose position of uridine-2479 in 23S ribosomal RNA. Confers resistance to antibiotic avilamycin, an orthosomycin antibiotic.
Interaction partners:
Sequence:
MARSRGERTPAARRITSRNARFQQWQALLGNRNKRTRAGEFLVMGVRPISLAVEHGWPVRTLLYDGQRELSKWARELLRTVRTEQIAMAPDLLMELGEKNEAPPEVVAVVEMPADDLDRIPVREDFLGVLFDRPTSPGNIGSIIRSADALGAHGLIVAGHAADVYDPKSVRSSTGSLFSLPAVRVPSPGEVMDWVEARRAAGTPIVLVGTDEHGDCDVFDFDFTQPTLLLIGNETAGLSNAWRTLCDYTVSIPMAGSASSLNAANAATAILYEAVRQRISGRTATTP
Protein: Zinc finger and BTB domain-containing protein 7C (Zinc finger and BTB domain-containing protein 36) (Q8VCZ7)
Organism: Mus musculus (Mouse)
Function: May be a tumor suppressor gene.
Interaction partners:
- Ankyrin repeat domain 65
Sequence:
MANDIDELIGIPFPNHSSEVLCSLNEQRHAGLLCDVLLVVQEQEYRTHRSVLAACSKYFKKLFTAGSLASQPYVYEIDFVQPEALAAILEFAYTSTLTITASNVKHILNAARMLEIQCIVNVCLEIMEPGGSVGEEDDKEEEDEDDDDEDEDDEEEEEEEEEEEEDDPEDFADQENLPDPQDITCPQSPSKTDHLTEKDYSDTPRDFPDSFQPGSPGHLGVIRDFSIESLLRENLYPKANIPDRRPSLSPFAPEFFPHLWPGGFGAFAQLPEQPMDSGPLDLVIKNRKIKEEDKEELAPPPPPPFSSDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGSLFPPWPLVEERKLKPKASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCSICEVRFTRQDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRGRKPAAWRAASLLFGPGGPSADKAAFVMPPALGDVGGHLGGTAVCLPGPSPAKHFLASPKGTLSLQELERQFEETQMKLFGRAQLEAERNAGGLLALALAENVAATRPYFPLPDPWAAGLAGLPGLTGLNHVASMSEANN
Protein: Coiled-coil domain-containing protein 106 (Q9BWC9)
Organism: Homo sapiens (Human)
Function: Promotes the degradation of p53/TP53 protein and inhibits its transactivity.
Subcellular location: Nucleus {ECO:0000269|PubMed:20159018}. Note=Colocalizes with p53/TP53.
Interaction partners:
- Cellular tumor antigen p53
Sequence:
MNDRSSRRRTMKDDETFEISIPFDEAPHLDPQIFYSLSPSRRNFEEPPEAASSALALMNSVKTQLHMALERNSWLQKRIEDLEEERDFLRCQLDKFISSARMEAEDHCRMKPGPRRMEGDSRGGAGGEASDPESAASSLSGASEEGSASERRRQKQKGGASRRRFGKPKARERQRVKDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLALDDETLKKVQALKKSKLLLPITYRFKR
Protein: 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (Q9LFL9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic
- 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic
- 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
- 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic
- 1-deoxy-D-xylulose-5-phosphate synthase
- 1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic
- Hydroxymethylglutaryl-CoA synthase
- 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic
- Aldolase-type TIM barrel family protein
Sequence:
MGSASIGYQFGISARFYGNFNLSSDITVSSLPCKLDVSIKSLFSAPSSTHKEYSNRARVCSLPNTDGYCDEKFETPILDSIETPLQLKNLSVKELKLLADEIRTELHSVLWKKTQKSMNPSFAAIELTLALHYVFRAPVDNILWDAVEQTYAHKVLTRRWSAIPSRQNSGISGVTSRLESEYDSFGTGHGCNSISAGLGLAVARDMKGKRDRVVAVIDNVTITAGQAYEAMSNAGYLDSNMIVILNDSRHSLHPNMEEGSKASISALSSIMSKIQSSKVFRKFRELAKAMTKRIGKGMYEWAAKVDEYARGMVGPTGSTLFEELGLYYIGPVDGHNIEDLVCVLREVSSLDSMGPVLVHVITEGNRDAETVKNIMVKDRRTYSDCFVEALVMEAEKDRDIVVVHAGMEMDPSLLTFQERFPDRFFNVGMAEQHAVTFSAGLSSGGLKPFCIIPSAFLQRAYDQVVHDVDRQRKAVRFVITSAGLVGSDGPVQCGAFDIAFMSSLPNMIAMAPADEDELVNMVATAAYVTDRPVCFRFPRGSIVNMNYLVPTGLPIEIGRGRVLVEGQDVALLGYGAMVQNCLHAHSLLSKLGLNVTVADARFCKPLDIKLVRDLCQNHKFLITVEEGCVGGFGSHVAQFIALDGQLDGNIKWRPIVLPDGYIEEASPREQLALAGLTGHHIAATALSLLGRTREALLLMS
Protein: Telomere repeat-binding protein 4 (H-protein promoter binding factor-1) (AtTBP1) (Telomeric DNA-binding protein 1) (Q9FFY9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds specifically to the plant telomeric double-stranded DNA sequences 5'-TTTAGGG-3'. At least 2 repeats of telomeric sequences are required for binding. Induces DNA bending.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:12909688, ECO:0000269|PubMed:17272298}.
Interaction partners:
- Sister chromatid cohesion 1 protein 4
- Large ribosomal subunit protein uL15x
- Large ribosomal subunit protein eL27z
- Double-strand break repair protein MRE11
Sequence:
MVVKRKLNCGGSNGFDFPNIPKAPRSSRRKVSGKRSDDESEICAIDLLASLAGKLLEESESSSTSTYASEADNLDHLGGLIKQELEDGYTTKPCKSEFFDPGNPASKSTSENTSVTCLPFSSFENDCILEQTPVSDCKRASGLKSLVGSITEETCVVNEDAGSEQGANTFSLKDPSQLHSQSPESVLLDGDVKLAPCTDQVPNDSFKGYRNHSKLVCRDDDENYCKYYKFSDKCKSYRPLSRVGNRRIMQSVRAISKLKCFEDTRTDGRLKALYRKRKLCYGYNPWKRETIHRKRRLSDKGLVVNYDGGLSSESVSNSPEKGESENGDFSAAKIGLLSKDSRVKFSIKSLRIPELVIEVPETATVGLLKRTVKEAVTALLGGGIRIGVLVQGKKVRDDNNTLSQTGLSCRENLGNLGFTLEPGLETLPVPLCSETPVLSLPTDSTKLSERSAASPALETGIPLPPQDEDYLINLGNSVENNDELVPHLSDIPADEQPSSDSRALVPVLALESDALALVPVNEKPKRTELSQRRTRRPFSVTEVEALVSAVEEVGTGRWRDVKLRSFENASHRTYVDLKDKWKTLVHTASISPQQRRGEPVPQELLDRVLGAHRYWTQHQMKQNGKHQVATTMVVEAGSSM
Protein: Small ribosomal subunit protein uS19u (40S ribosomal protein S15-1) (Q08112)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm.
Interaction partners:
- Small ribosomal subunit protein eS24z
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein eS28x
- Small ribosomal subunit protein eS21z
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein eS25w
- Small ribosomal subunit protein eS19z
- Small ribosomal subunit protein eS6y
- Small ribosomal subunit protein uS13z/uS13y/uS13x
- Small ribosomal subunit protein eS10z
Sequence:
MADVEPEVAAAGVPKKRTFKKFAFKGVDLDALLDMSTDDLVKLFSSRIRRRFSRGLTRKPMALIKKLRKAKREAPQGEKPEPVRTHLRNMIIVPEMIGSIIGVYNGKTFNQVEIKPEMIGHYLAEFSISYKPVKHGRPGVGATHSSRFIPLK
Protein: Lactotransferrin (Lactoferrin) (EC 3.4.21.-) [Cleaved into: Lactoferricin-B (Lfcin-B)] (P24627)
Organism: Bos taurus (Bovine)
Function: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
Subcellular location: Secreted. Cytoplasmic granule {ECO:0000250}. Note=Secreted into most exocrine fluids by various endothelial cells. Stored in the secondary granules of neutrophils (By similarity). {ECO:0000250}.
Interaction partners:
- Beta-lactoglobulin
- Alpha-lactalbumin
- Albumin
- Peptidase S1 domain-containing protein
- Lactoperoxidase
- Myeloperoxidase
- Beta-casein
- Transferrin receptor protein 1
- Toll-like receptor 4
- Clusterin
Sequence:
MKLFVPALLSLGALGLCLAAPRKNVRWCTISQPEWFKCRRWQWRMKKLGAPSITCVRRAFALECIRAIAEKKADAVTLDGGMVFEAGRDPYKLRPVAAEIYGTKESPQTHYYAVAVVKKGSNFQLDQLQGRKSCHTGLGRSAGWIIPMGILRPYLSWTESLEPLQGAVAKFFSASCVPCIDRQAYPNLCQLCKGEGENQCACSSREPYFGYSGAFKCLQDGAGDVAFVKETTVFENLPEKADRDQYELLCLNNSRAPVDAFKECHLAQVPSHAVVARSVDGKEDLIWKLLSKAQEKFGKNKSRSFQLFGSPPGQRDLLFKDSALGFLRIPSKVDSALYLGSRYLTTLKNLRETAEEVKARYTRVVWCAVGPEEQKKCQQWSQQSGQNVTCATASTTDDCIVLVLKGEADALNLDGGYIYTAGKCGLVPVLAENRKSSKHSSLDCVLRPTEGYLAVAVVKKANEGLTWNSLKDKKSCHTAVDRTAGWNIPMGLIVNQTGSCAFDEFFSQSCAPGADPKSRLCALCAGDDQGLDKCVPNSKEKYYGYTGAFRCLAEDVGDVAFVKNDTVWENTNGESTADWAKNLNREDFRLLCLDGTRKPVTEAQSCHLAVAPNHAVVSRSDRAAHVKQVLLHQQALFGKNGKNCPDKFCLFKSETKNLLFNDNTECLAKLGGRPTYEEYLGTEYVTAIANLKKCSTSPLLEACAFLTR
Protein: Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (EC 2.7.1.68) (Q503I3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Phosphatidylinositol-3-phosphatase SAC1-A
- Phosphatidylinositol-3-phosphatase SAC1-B
- Phosphatase and tensin homolog A
- Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A
- Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-B
- Phosphatidylinositol-4,5-bisphosphate 4-phosphatase
- Actin, cytoplasmic 1
- Vinculin a.
- Actin, cytoplasmic 2
- Vinculin b.
Sequence:
MAAPAVVSTDGADSSTPGNRKMASSEGLSTLGSSQTNKKTLGHRGIDPTGETTYKKTTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHRAGEEASTAVPDTQKKGQGQKPLYCTAIESIQGESKSKTSPQPYESMGGIPAFNSKGERLLVFIGIIDILQSYRLVKKLEHSWKALLHDGDTVSVHRPSFYADRFQKFMCSTVFRKSQLKTSPSKRSRLGPVSAGKKSNIAVSGQSHQQSLPVAAELTQSQLWSSEDPQGDSGMQTARPDLLPQQVAEDDITSSSADTTLSATSLVNSRLSTNTPVLSRSSVAGHSSEESLDMDVISLSEIVPQTSTSE
Protein: 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (DAROPP reductase) (DARP reductase) (EC 1.1.1.302) (2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase) (2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase) (DARIPP synthase) (Q9P7L3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
Interaction partners:
- Probable GTP cyclohydrolase-2
- Riboflavin synthase
- Diaminohydroxyphosphoribosylamino-pyrimidine deaminase
- 6,7-dimethyl-8-ribityllumazine synthase
- 3,4-dihydroxy-2-butanone 4-phosphate synthase
- Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase
Sequence:
MESSQAYFPPSANKKHVLLTWAQSINGRIGYVVESPSLGQLRLSSKESFVMTHLLRTKFDGIMVGSRTAENDNPSLTAKLPDPANPDCLLPLNKQPIPIIVDSNLRLDYASLKVIRLARERLGKPPLIIVAPSIWQQVQHDSKLKEAVKLIQSVGGRCIIRNEDSPDSWSDYVALDKLLQNGVNRIMVEGGAELLAKAFGSTDIDAYVVTIVPKIFSCSNTTEIKNLNNLNLTTNSHWYPCGPDVIFTNYSDEFYESYKSLLTNSDAI
Protein: Multifunctional fusion protein [Includes: Ribulose bisphosphate carboxylase small subunit (RuBisCO small subunit); Ribulose bisphosphate carboxylase small subunit, chloroplastic] (Q36688)
Organism: Oryza sativa (Rice)
Subcellular location: Plastid, chloroplast {ECO:0000256|HAMAP-Rule:MF_00859}.
Interaction partners:
Sequence:
MASSATTVAPFQGLKSTAGMPVARRSNSSFGNVSNGGRIRCMQVWPIEGIKKFETLSYLPPLTVEDLLKQIEYLLRSKWVPCLEFSKVGFVYRENHKSPGYYDGRYWTMWKLPMFGCTDATQVLKELEEAKKAYPDAFVRIIGFDNVRQVQLISFIAYKPPGCEESGGN
Protein: Gametogenetin-binding protein 1 (Q6K1E7)
Organism: Mus musculus (Mouse)
Function: Induces mitochondrial fragmentation, possibly by promoting DNM1L-dependent fission and may play a role in mitochondrial morphogenesis during spermatogenesis.
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus. Mitochondrion intermembrane space.
Interaction partners:
- Gametogenetin-binding protein 2
- Gametogenetin
- Ornithine decarboxylase antizyme 3
Sequence:
MAAPARTPRSRILGCSSMLRFLRNLVGSKGGSKSTNKPLTRSQPSSSWEQDVVSPMMGHQGGRGRKEPRAKVHSAASSNGKREPPPRVLSAAPSNPRHDAFELGTGDSGSQTLTSKDVPKLRAQGVEVTSVPLRGTWEVLEQLPEKKGEEEEPVGEVSGASDREHFGQALETEQGCLQWVPGPLALTPGAFIKEEEDEHCPIEFGDLKPSSCKVGSTPWNYLLGLYKQLQKSAMAKAQRPAAPQLALKDGLPHEEKGEREEAVDESCPKWCAPRASSDESCPKWCAPRASTYQSPLQKKFRSTDTVGFVESELKKILSVQREARLWKVGNPEGRELLTQPDITLEEAGMVDGQHLLLEEMDEMGNWPPPD
Protein: Ubiquitin-associated protein 1 (UBAP-1) (F6P6X0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9NZ09}. Endosome {ECO:0000250|UniProtKB:Q9NZ09}. Note=Predominantly cytosolic. Recruited to endosomes as part of the ESCRT-I complex. {ECO:0000250|UniProtKB:Q9NZ09}.
Interaction partners:
Sequence:
MAARKSGSDIHNNGPVSYLDDVPFKLNEKFRCPSKVGLPIGFCLSDCNAILSDLQYDFNLERRTVQWGEELAKARAAEARAAEAIRTDSESERQAASQDAEVGLVGGKKARPSDEQDIVPPALKPVLAGLSHNAILTPLPAPSFGQTRPAPSNPAPQYLNLADFEREEDPFDKLELKTLDDKEELRTILQSQPQSSVSPPQLPPAEHRPVSPSTTPPLQAKTGIFHKPNGLVGLLDLDRGGVLGGQIDADRPCNIRSLTFPKLSDPGDSPLETPLSVYPVAPPRNLSNGTPPSLQRTASNNNTTLPQEQPVFAQNGTPKQSNPVTVTSHPPAGTTLLSLSPSERQCVETIVGMGYSYEGVLKAMQRQGQNVEQVLEYLFTHSRLCDRGFDATAVEECLEMYQGSEEKALEFLQLMSRFGEMGFERDTIKEVLLVHNNDQDKALEDLMTRATAS