wanglab/gogpt-training-data huggingface dataset:
Protein: Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33) (Q8BN78)
Organism: Mus musculus (Mouse)
Function: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). May recruit the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Contributes to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:10207085, ECO:0000269|PubMed:15282317, ECO:0000269|PubMed:15564377}.
Interaction partners:
- Catenin delta-1
- Nuclear receptor corepressor 2
- Nuclear receptor corepressor 1
- Transcriptional repressor CTCF
Sequence:
MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKVVRVRADLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTEQDGTAETLPSSSSDKSLDMEKSKDEAQDNGATVMPIITESFSLSAEDNEMKKIIVTDSDDDDDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVAISEVTPCASNNSPPVTNITPTQLPTPVNQATLSQTQGSEELLVSSASTHLTPNIILLNQAPLTAPPSASSSLPNHMSSSVNVLVQNQQTPNSAVLTGNKAEEEEEIIDDDDDIISSSPDSAVSNTSLVPQADNSKSTTLDGSLTQKMQIPVLPQEPPSNSLKISDVITRNTNDPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDGGEAKLDNELPKTSGSEPPNKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYQCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCKSLQIRQYAYLSNKSSAMPVMKDDAVGYKVDAGKEPPVGTTSTPPQNKSTFWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY
Protein: Dystrophin-related protein 2 (DRP-2) (Q13474)
Organism: Homo sapiens (Human)
Function: Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane. Possibly involved in membrane-cytoskeleton interactions of the central nervous system.
Subcellular location: Postsynaptic density {ECO:0000250|UniProtKB:Q9EPA0}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9EPA0}. Perikaryon {ECO:0000250|UniProtKB:Q9EPA0}. Cell membrane {ECO:0000250|UniProtKB:Q05AA6}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q05AA6}. Note=Detected in Schwann cells at periaxonal myelin membranes. {ECO:0000250|UniProtKB:Q05AA6}.
Interaction partners:
- Periaxin
- Dystroglycan 1
Sequence:
MQPMVMQGCPYTLPRCHDWQAADQFHHSSSLRSTCPHPQVRAAVTSPAPPQDGAGVPCLSLKLLNGSVGASGPLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATESKGELQKILAHLEDENRILQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHPREKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS
Protein: Small-subunit processome Utp12 domain-containing protein (Q57VR1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Telomerase-associated protein, putative
Sequence:
MTERSLLIRCTQAGRYLAVGMDFPSARVFDVATGNLAAVVNVPAQNRFSLAVVSLTSLSLGIVNERVEQQQSTRKRGKEGRKTDCTLYTTFAAVGLSNGTLLLHNVGKDELVGHLCVSDTQQAVVATAFTGHFLLCVTADRLLHVVDCIRGERIVTNLRVQHDASAIAAVEDVVTSAGRDDFIPESVFCIFISGPTNALYRLRIGNNATSGDVGGVHSAVTASLDRLITFASHTSRTDIAWMGGTPQQPVVITSNAQEGAVRVWDARPSLDGSTATSRCRRSLMCGQRIIGISVREGASSGDDRGLDGMNDLPSAANNGAKGEGDIGRMSDGGALVVVTTFTGTVLVWMLGRSLLVAVAEPMPRPPTFQLTSQDESGRLLFASLLPGANAADGSSSSACSSLLLLRGRFAVPQFEVLDLCDAMSKAVKLKGSAAARRRTALVAGGGEVAVYFVPSDTQSKASADLVAYNDLETLDNAWATHDQQQQRRILLAARATRAGTEGFVPAVSYHAKSVSELPQKSLTLEQRLKQLHVSESNESTAGQQQQQHALGLATVPLYQALHANDTSAVMELLTVASRSSGDIRATVMSLQLPYCLQLLQLLGQRVRGASPCSPLFQWIDAIIRYRGVEMYQVQQDLKQKSAVSSSDGATKGIKPDQPSPPKDFVAPLLHQYRNMVSLYDQIAVMYGRLSIFKSVFPSERNVSANSHGDIIFPKMFVEKKYSGGLYSTATTERKVDSLSSKRRKSRKDGNKKKGARPSSKSKRKAKKGAAASKENEEEDNDMDSDEELDLDALDQMVLSDGDVNEEDDVDDNSSGTDDEEEGNSEVSDEEEEGDEDATEDDEEDEGDAIHKKKRARGEQTTAMVAESERGSSYGMESRHSGEEDFDSGSDEEVGLAAAPSDGSDDEESADDSESDSTSSGRSGADDIPDGNFDDDDDEDDLDEEDDGIGSDVAELLNNGRNGDDESDDEERHELRRYKRAKADG
Protein: Zinc finger CCCH domain-containing protein 47 (AtC3H47) (AtSZF1) (Q93ZS9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in salt stress response. May positively modulate plant tolerance to salt stress.
Subcellular location: Nucleus {ECO:0000269|PubMed:17609218}.
Interaction partners:
- Zinc finger protein ZAT10
- At2g39650
- Zinc finger CCCH domain-containing protein 37
- Zinc finger CCCH domain-containing protein 15
- Probable inactive poly [ADP-ribose] polymerase SRO2
- Zinc finger CCCH domain-containing protein 14
- SH3 domain-containing protein 1
- Zinc finger CCCH domain-containing protein 17
- NAC domain-containing protein 62
- Putative RING-type E3 ubiquitin transferase C3H69
Sequence:
MCSGPKSNLCSSRTLTEIESRQKEEETMLLLEFAACDDLDSFKREVEEKGLDLDESGLWYCRRVGSKKMGLEERTPLMVAAMYGSIKVLTFIVSTGKSDVNRACGEERVTPLHCAVAGCSVNMIEVINVLLDASALVNSVDANGNQPLDVFVRVSRFVASPRRKAVELLLRGGGVGGLIDEAVEEEIKIVSKYPADASLPDINEGVYGSDEFRMYSFKVKPCSRAYSHDWTECAFVHPGENARRRDPRKYPYTCVPCPEFRKGSCPKGDSCEYAHGVFESWLHPAQYKTRLCKDETGCARKVCFFAHKREEMRPVNASTGSAVAQSPFSSLEMMPGLSPLAYSSGVSTPPVSPMANGVPSSPRNGGSWQNRVNTLTPPALQLNGGSRLKSTLSARDIDMEMEMELRLRGFGNNVEETFGSYVSSPSRNSQMGQNMNQHYPSSPVRQPPSQHGFESSAAAAVAVMKARSTAFAKRSLSFKPATQAAPQSNLSDWGSPNGKLEWGMKGEELNKMRRSVSFGIHGNNNNNAARDYRDEPDVSWVNSLVKDSTVVSERSFGMNERVRIMSWAEQMYREKEQTVV
Protein: BTB domain-containing protein (Q18986)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MEPSTIVKLDVGGKIFKTTIFTLCKHDSMLKTMFCTDVPVTKNEEGSVFIDRDSKHFRLILNFLRDGQIALPDSDREVREVLAEASYFLLDPLIELCGERLEQSLNPYYHLVSTVLEARKIIFATEKPIVVLRLPVYIATSGNQSYYFSETKFRELSEEYHKHVAFILITEPEFNEDCSWSFFLRAKKITARIKGPMDCNLVEECMQKLLKDAEKRRRGTKSFFNEIPMELVEHEELH
Protein: Fibroblast growth factor 19 (FGF-19) (O95750)
Organism: Homo sapiens (Human)
Function: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Subcellular location: Secreted.
Interaction partners:
- Beta-klotho
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor 1
- Klotho
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Bile acid receptor
- Protein LTO1 homolog
- Immunoglobulin lambda-like polypeptide 5
- Immunoglobulin heavy variable 3-43D
Sequence:
MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
Protein: APC-like, isoform C (A0A126GV30)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLEPTLTPDLEEGIAELSLEDVDVDSVPERKPHFLDYDAVPPPDYEEGFGASSGEQLKMDKKYERDGEVSDYELAASGYTKKEFTQDDNTLHFTQSAVGLGSGAVGKKPAAKHFLDENPIPPDYMLAQELREMREHRSLDRNFERQSAQQQQLDELPPRNGGGSPASAGRPSRSKEPSYTLSRFLDGDAPAPAPRLPKGAAWTTSFDERYTSSAVEATLGSKVECVYSLLSMLGSNDPLEMAKKFLELSGNAQSCATLRRSGCMPLLVQMMHAPDNDQEVRKCAGQALHNVVHSHPDEKAGRREAKVLRLLDQIVDYCSFLKTLLQSGGEAIADDSDRHPLAAISSLMKVSFDEEHRHAMCELGALHAIPNLVHLDHAVHGPKPEDQCCNSLRRYALMALTNLTFGDENNKALLCGQKQFMEALVAQLDSAPDDLLQVTASVLRNLSWRADSNMKAVLNEIGTVTALALAAMRNRSENTLKAILSALWNLSAHCSTNKAEFCAVDGALAFLVGMLSYEGPSKTLKIIENAGGILRNVSSHIAVCEPYRQILRQHNCLAILLQQLKSESLTVVSNSCGTLWNLSARSAEDQKFLWDNGAVPMLRSLIHSKHAMISEGSSSALKNLLNFRPAVQNHHQLDPIARSMGLKALPTLEARKAKALQQELGERHTAETCDNLDTGGKLDKERASSSSRRHPAPRLTRSAMLTKSESRDSVYSAKSDCAYDHLIRSASASDAHRKVKPKITDFDLEMEQDTEATEEQPIDYSVKYSENATKTSTYQETDLDQPTDFSLRYAENQIESDLDISGPAGGQKSTITPPAETVPEKSEGQEILLILDDSVKCYQTEDTPYVISNAASVTDLRVAAKADAEAEVKPEVREVTSKEGAPKKLPKLSQCGSGSYTPEKPINYCEEGTPGYFSRYDSLSSLDESGKANQAIVGTDADIKPKLEKQEEQESQPAEQVLTKPPTQANSALETPLMFSRRSSMDSLVHDPDVDVANCDDKSSVVSDFSRLASGVISPSEIPDSPTQSMPQSPRRNSVAGSGQNVDSPPVVIPASLQPLRSVFEDDLSSFNVEHTPAQFSTATSLSNLSIVDDEKAPASVAEEDNEDELLLANCINMGMQRKPTEAVKSTVVNSEVDVAEETIRSYCTEDTPALLSKVPSNTNLSVISMSSTDPKDATAGQAQMYAHQLSDDVSSNASDCGGASGHLLQQCIRDGMKKPLGEATSDPIAMLRRGGNELPGYLPSADEMNKFLVEDSPCNFSVVSGLSNLTVGSSLVGPAVQLKETEPSSADQNPEMKAKPGKQEQVRRPPHWQDDSLSSLSIDSEDDTNLLSQAIAAGCNRPKSNLGFSSNGKRSSSLSSSQPIAINAATSASSLNSAMTVRKSQQQESYSSVDSSDSNDNQSKSLFELCILKGMYKTKEPGARAQQMQEQPIVGSSSVQSNPSLKQFDSLPVQLPSSGQVKRQRHHHHHHHHRERERERKDEKLLQECINTGISKKINAVPKKRPGYVCGCIGTVSPNGSYYISKCPQHSSSRRRAESARHQQSAAAVVHAPEQPHPPESYRRHRHRHRHSKKSSSSKSRERERESERSRDRYWV
Protein: Trehalose-6-phosphate synthase (TPS) (EC 2.4.1.15) (Alpha,alpha-trehalose-phosphate synthase [UDP-forming]) (Osmoregulatory trehalose synthesis protein A) (OtsA) (UDP-glucose-glucosephosphate glucosyltransferase) (P31677)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. Essential for viability of the cells at low temperatures and at elevated osmotic strength.
Interaction partners:
- Trehalose-6-phosphate phosphatase
- Trehalose-6-phosphate hydrolase
- UTP--glucose-1-phosphate uridylyltransferase
- Glucose-1-phosphate adenylyltransferase
- PTS system trehalose-specific EIIBC component
- UTP--glucose-1-phosphate uridylyltransferase
- Cellulose synthase catalytic subunit
- Catalase HPII
- PTS system glucose-specific EIIA component
- Osmotically-inducible protein Y
Sequence:
MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSGETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPAWDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPTPEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKAFRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLAYEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLYYLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAANELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISDLKQIVPRSAESQQRDKVATFPKLA
Protein: Quick-to-court, isoform I (Q7KTP6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MANGKPRNLSLQLNGGSDISSSGTSSSSSNNKESSPRTTRTPRTPQTPQTPQTPASGVAASVAETPHSCIRQGNCVKANQVKLSTLHESKISPRTPPVTPDSPSTYLDDDIDSMYSFATTTSGRSTMSCEHPYVARNGTTFSGRKMKYVVHCSNYAGQVGPDYLTPTQRAQRQIRRLKELLCIARQDLEQKDTELLRLTREVVELRLFKASLSSPEERSASSDAVTVREAELKTSQDVSPIVDMVDEGNAKGSPRHLSRQQQQQANHSLQAMQMSAEMQSSYADSGHFEDLTMSSVHSKDSQTQSEACGTATPDGEADVGCGAGGDSASNLENYELQRQELISMYEHRIEELIRSQDSATSDLKRSHNDKVEALLQKLAECNTRYSDMVPDYEQAKQRIRELEKQLEDLQRKLIEHEEKQNKMYLHMYQQGQEAERISRADQALDLAQRQPESKVSINELLHQLQSTQDELENIRASECRMRECGSNHALLTAKEAISLWVLGARKTIYRRLLEAQKNRTHVDPEVTLQFLKSAIFYFLTDKENSQGHLQAIESILEFTDAEKQKISAANRTPK
Protein: RNASEK-C17orf49 readthrough (H0YIS7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XDFENGPQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVGEIFSAAGAAFTKLGELTMQLHPVADSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKATVKRKVYEDSGIPLPAESPKKGPKKVASGVLSPPPAAPPPSSSSVPEAGGPPIKKQKADVTLSALNDSDANSDVVDIEGLGETPPAKKLNFDQDSLTLDSGLLMTSADPPLLSC
Protein: Adamts3 protein (B2RY45)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MVFLSLWLIAASLVEVRTSADGQAGTDEMVQIDLPTKRYREYELVTPVSTNLKGHYLSHILSANHKKRSPRDVSSNSEHLFFNVTAFGRDFHLRLKPNTHFIAPGAVVEWHETAPRPGNTTDPRDSHLHGSASEGSWRSEPLQTSCAYVGDIMDIPGTSVAISNCDGLAGMIKSDDEEYFIEPLERGKQMDEENGRIHVVYKRSAVEQPPRDVSEDVYHRESDLEGLDDLGTVYSNIGQQLNKTMRRRRHTGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKTDPNHAEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFDYQNTKHHWLPHEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDREIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGKTRGAFVLPKGARNISLAETRETKNVLAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSEPCGGGFQYTKYGCRRKSDSKMVHRSFCEVNKKPKPIRRMCNIQECTHPVWAADEWEHCSRSCGSSGNQLRTVRCLQPLQDGTNRSVHSKYCLGDRPESRRPCNRVPCPAQWKTGSWNECSVTCGEGTEVRQVLCRTGDHCDGEKPESVRPCQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSGTLPPPYLQEAAEIHSDAIFGPSDLPRSLVMPTPFLPSSSGTRAEKKSLSSFSSMANPNADAAFRASSRASADFPRKRAHQAGRKTLESVPSSSSIKTDHLRPASPVAAAPSPAISDSIGASPQTRTPKKDDAKSVSRRHPTRSTASER
Protein: Centrosomal protein of 162 kDa (Q57ZR1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Acyl carrier protein
Sequence:
MHAGGTSSNSSGHDPVMDDIAELKALLQNGGLTSDILEGKYLNQLRRARQLNVQLETERTRARQLTVQLEALREEKRKAGDRNSEQAGKEGRRRRQSSERATNNESDEGQQNVTALRERLDRAFVQLSDAKVQLEEQKKESQRLRKIIQQEVGNPPQDIEALLKGSSDSSRGWRGRAQQIVLLKSKVKELERALGATGGSSPAAIDGGGTPCVTKTSTLSLTTDAVTTTTAGVRDRDDVAREHVVELQSRRLLQQRELQDELARQKAELDSMKLRLTASQSRHANLEADNRQLREHLQAVLQKTQNDNDLIDAYREEMEELRHVKVELHQAKVELQKWEEWCSSAQQRNPRELERLEEQTPGMCDKSRDARYRTDGGDAGIDVNTAVALAGADTAIELNRLRLENLQLKSLLTRYEDHGDGGALGNESPTGQNKGQQDDMALLMHWLKSFISPRSGEADTNKGVGSQAVVSDSVVGVDWQGRVAEVLRRAHSAVTFLEKQQQEQGERLSKCYETIRQLQAELKQRPGKREKKPKGNHVGDGDATGGEKDDDDGELVNILLQENVALKQRVKVMQDLLNKERAAYESLRSFSAASGTSDAPTAAAYLKLKRDYEELRAAFNCAQAELLRNDAA
Protein: Ig lambda-2 chain C region (P01844)
Organism: Mus musculus (Mouse)
Interaction partners:
- Immunoglobulin J chain
- Immunoglobulin lambda-like polypeptide 1
- Ig heavy chain V-III region J606
- B-cell antigen receptor complex-associated protein alpha chain
- Immunoglobulin heavy variable V6-4
- B-cell antigen receptor complex-associated protein beta chain
- High affinity immunoglobulin epsilon receptor subunit beta
- Tyrosine-protein kinase Lyn
Sequence:
QPKSTPTLTVFPPSSEELKENKATLVCLISNFSPSGVTVAWKANGTPITQGVDTSNPTKEGNKFMASSFLHLTSDQWRSHNSFTCQVTHEGDTVEKSLSPAECL
Protein: Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) (O70468)
Organism: Mus musculus (Mouse)
Function: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Interaction partners:
- Myosin-6
- Myosin-7
- Troponin I, cardiac muscle
- Troponin T, cardiac muscle
- Myosin light chain 3
- Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
- Telethonin
- Actin, alpha cardiac muscle 1
- Tropomyosin alpha-1 chain
- Alpha-actinin-2
Sequence:
MPEPGKKPVSAFNKKPRSAEVTAGSAAVFEAETERSGVMVRWQRDGSDITANDKYGLAAEGKRHTLTVRDASPDDQGSYAVIAGSSKVKFDLKVTEPAPPEKAESEVAPGAPEEVPAPATELEESVSSPEGSVSVTQDGSAAEHQGAPDDPIGLFLMRPQDGEVTVGGSIVFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQTTSAGGYRCEVSTKDKFDSCNFNLTVHEAIGSGDLDLRSAFRRTSLAGAGRRTSDSHEDAGTPDFSSLLKKRDSFRRDSKLEAPAEEDVWEILRQAPPSEYERIAFQHGVEACHRPLKRLKGMKQDEKKSTAFQKKLEPAYQVNKGHKIRLTVELADPDAEVKWLKNGQEIQMSGSKYIFESVGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRSLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGRKHHLIINEATLEDAGHYAVRTSGGQSLAELIVQEKKLEVYQSIADLAVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDNRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGSTPDTIVVVTGNKLRLDVPISGDPAPTVVWQKTVTQGKKASAGPHPDAPEDAGADEEWVFDKKLLCETEGRVRVETTKDRSVFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPVLGYILERKKKKSYRWMRLNFDLLRELSHEARRMIEGVAYEMRVYAVNAVGMSRPSPASQPFMPIGPPGEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCQEGCSEWTPALQGLTERRSMLVKDLPTGARLLFRVRAHNVAGPGGPIVTKEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRTHSGTYQVTVRIENMEDKATLILQIVDKPSPPQDIRIVETWGFNVALEWKPPQDDGNTEIWGYTVQKADKKTMEWFTVLEHYRRTHCVVSELIIGNGYYFRVFSHNMVGSSDKAAATKEPVFIPRPGITYEPPKYKALDFSEAPSFTQPLANRSIIAGYNAILCCAVRGSPKPKISWFKNGLDLGEDARFRMFCKQGVLTLEIRKPCPYDGGVYVCRATNLQGEAQCECRLEVRVPQ
Protein: RuvB-like helicase (EC 3.6.4.12) (Q8IAT2)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RuvB-like helicase
- DNA methyltransferase 1-associated protein 1, putative
- Zinc finger protein, putative
- Probable ATP-dependent helicase PF08_0048
- Actin-related protein, putative
- PIH1 domain-containing protein, putative
- Nucleolar protein 5, putative
- YL1 nuclear protein, putative
- Histone H2A
- PI3K/PI4K catalytic domain-containing protein
Sequence:
MNIIESSREKERISLHSHISGLGLDADGYVTDFLFEENIKKRDMYSEPTNKIENNDIKNGTILDPDKVDNICNSYKLENNGNYENNKICYNNISDDEDEVVKNFYKCKGMVGQKKAREAAGIFINLIKEKNICKCLLLAGPSGSGKTAIAIAISKEISDESIPFCIFNASQVYSCEVKKTEILTQYIRKSIGVKIKEIKEVFEGEVVQIEPFFDNTYDEQKISYVHITLKTLKEQKKIKIHSSIYDNLLKEKIQEKDIIYIESHSGNVKRVGKCSLYQDMFDIETDTFVDLPKGNVHKKKNIIQNITLYDLDVSNVQPKDNILDFLQNNKSKKTEITDKLRNEINKIVYKYVDQGIAQIIPGVLFIDEVHMLDIECFTYLNRTLESNLAPVVILATNRGICNIKGTNIISAHGIPVDLLDRIIIVKTMLYNKEEILQVLKLRCKFERIKIDSEALDYLSDIGIKCSLRYAIQLLTPAKILSKKKGKKKIDKNIIEIVSSIFFDTKRSTQLLLNDKNKYMY
Protein: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (GMP-PDE alpha) (EC 3.1.4.35) (PDE V-B1) (P11541)
Organism: Bos taurus (Bovine)
Function: Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. This protein participates in processes of transmission and amplification of the visual signal.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P16499}; Lipid-anchor {ECO:0000250|UniProtKB:P16499}; Cytoplasmic side {ECO:0000250|UniProtKB:P16499}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P16499}.
Interaction partners:
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
- Guanine nucleotide-binding protein G
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanylate kinase
- Retinal guanylyl cyclase 1
- Adenine phosphoribosyltransferase
- Guanylate cyclase
Sequence:
MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEIIFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAVLEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEDEHFCDFVDTLTEYQTKNILASPIMNGKDVVAIIMVVNKVDGPHFTENDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPPYAGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIMNAPSEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLTQFLGWSVLNPDTYELMNKLENRKDIFQDMVKYHVKCDNEEIQTILKTREVYGKEPWECEEEELAEILQGELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYETQQEWTQYMMLDQTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYETKMKGLEEEKQKQQAANQAAAGSQHGGKQPGGGPASKSCCVQ
Protein: RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Cyp60) (hCyP-60) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) (Rotamase PPIL2) (Q13356)
Organism: Homo sapiens (Human)
Function: Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:11435423, ECO:0000269|PubMed:8660300}. Note=May also localize to the cytoplasm and the cell membrane. {ECO:0000269|PubMed:15946952}.
Interaction partners:
- Pre-mRNA-processing factor 17
- E3 ubiquitin-protein ligase RNF113A
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
- Basigin
- Spliceosome-associated protein CWC27 homolog
- Pre-mRNA-splicing factor CWC22 homolog
- Serine/arginine repetitive matrix protein 2
- G-patch domain and KOW motifs-containing protein
- Serine/arginine repetitive matrix protein 1
- Microfibrillar-associated protein 1
Sequence:
MGKRQHQKDKMYITCAEYTHFYGGKKPDLPQTNFRRLPFDHCSLSLQPFVYPVCTPDGIVFDLLNIVPWLKKYGTNPSNGEKLDGRSLIKLNFSKNSEGKYHCPVLFTVFTNNTHIVAVRTTGNVYAYEAVEQLNIKAKNFRDLLTDEPFSRQDIITLQDPTNLDKFNVSNFYHVKNNMKIIDPDEEKAKQDPSYYLKNTNAETRETLQELYKEFKGDEILAATMKAPEKKKVDKLNAAHYSTGKVSASFTSTAMVPETTHEAAAIDEDVLRYQFVKKKGYVRLHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQGGDPTGTGTGGESYWGKPFKDEFRPNLSHTGRGILSMANSGPNSNRSQFFITFRSCAYLDKKHTIFGRVVGGFDVLTAMENVESDPKTDRPKEEIRIDATTVFVDPYEEADAQIAQERKTQLKVAPETKVKSSQPQAGSQGPQTFRQGVGKYINPAATKRAAEEEPSTSATVPMSKKKPSRGFGDFSSW
Protein: Spermatid perinuclear RNA-binding protein (A0A0S2Z5K8)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEVKKDEAGENYSKDQGGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGENVSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDPTDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRGTLTRGAFVGATAAPGYIAPGLPKRMVLLPVMKFPTYPVPHYSFF
Protein: Nucleoporin NSP1-like C-terminal domain-containing protein (A0A060VZ42)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
- Nucleoporin Nup54 alpha-helical domain-containing protein
- 54 kDa nucleoporin
- Nucleoporin 58
- E3 SUMO-protein ligase RanBP2
- Nucleoporin p58/p45
- Protein SEC13 homolog
- E3 SUMO-protein ligase RanBP2
- Nuclear pore complex protein
- Nuclear pore complex protein Nup205
- Nucleoporin Nup37
Sequence:
MSGGFNFGQASSTGFSFGAPKTTAATAPATGFGMPSAAAPGGGFSFGTPSTPQAPVAAPQSSGLFAMPTQGSTNPTGGFSFGTPAQSSTPAGGGFSFGTPIAKLNLGTPVASQPALTGLTMGMATPSSGTGFGLGGGLATQTTAAPAGGGFSFGTAGGLGAPVAQTQPQTQPAAAGGLSLGTPAEATQIMGGGFSFGAAKVQATTAPAPTVTVGGGFSFGNSTPASLSLGTQPTSLTLNSVASTAVPTTTQVGGFAFGVKPSATPAPTATAPATQASLGSSLFAVPASTAAPATAAITGFLGAAPTSAAPAATSTAGSTLGFMLKPLGAVTATTTAPVGTAAPTTTTGFSLAMKPAGAIGIGVTAPITGVATTIATVTASAPPVMSYMQLEGLINKWSLELEDQERHFLQQATQVNAWDRTLVENGEKITSLHREMEKVKLDQRRLDQELDFILSQQKELEDLLSPLEESVKEQSGTIYMQNADEERERTYKLAENVDAQLKRMSQDLKEIIEHLNTSSGPADNSDPLQQICKILNAHMDSLQWIDQNSVLLQRRVEDVSKLCDNRRKEQEKTFRITFH