wanglab/gogpt-training-data huggingface dataset:
Protein: Vacuolar protein 14 C-terminal Fig4-binding domain-containing protein (Q57WG8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
- Synaptojanin
- Synaptojanin
- Zinc finger protein, putative
- Non-specific serine/threonine protein kinase
- 1-phosphatidylinositol-3-phosphate 5-kinase
Sequence:
MGESFVPARSFKLLVDAKVELRQKGAKEVSQKVSTVFRSSSITEAYEITTKELHEIERSLLRTTSPTYRRGGMIAIRAIIASLPPRNHEQRLVEDLATIVFDSVADVDVSVRMAAFEAAHALVRNLQQQLLNFCFLRTFRGVACGISEGDKRVVLLAREVSSAIRELVTGNDNFSFKTELFVTFINETLVPFCCATGDEGSTHSAVVEWCLEWIYHVLNLPGDDFIIQLWQLLKPLLLLSGTCNGSEALSLLQKCLGKTKDAFTRHVDVRVAKLVSIACECVQDANAALAKKSALEWISELHTVGALELLDLTDGVVKACLSQLGSKDLETRLAAQKVNQKITQFIAAPRDDTKAIPYEAVLKGVLEQLADRSVEEVRVAALEWIVLVLHAAPDVLECCFDASFDTTVALLCDRSLHVVHKCIEVLCLISGEVHFDHFIARLVDLIHTKADVLLPKVPTIIKQLQLRYQEEDLGQCEKLCLKLADVVSSHKDKRFVEKFVITLNTMLLTSRELLPLREVLHRGVDDARAREAFLGLYNCFCYNTVSALSLCFLSRAYEHAYQLVRFMGSCEMSANTLVQLERLVRLIETPALSYVRIALMEPSKCLPLVRTLFAMQLILPQCSPQYMILYRRIKTIPSLARLEREDSANAVQGSNNAIWEQLLNQSKEAQRCTAEFERRFFLQQMGDADIL
Protein: Partner of drosha, isoform B (A0A0B4KI70)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRMIPIIRLACPVASDNASEQQGGRYGEGGDEEEEAADGDGEEYDSSEFDDDEIENLLDEKLPEELRESKQPKYEQRFKTVLEEKRLNHFEVLPEGWVQVTHNSGMPLFLHRKTRVCCASRPYFLGTGSARKHAVPLGAIPCLNYRRALEEESEVEQQKTDGAPPVAVCPMAGASALPAEAMDVEGKENNEGSTDSKTQPDGITALMPAAKIVTVNENTQKESITPEQLNTYCQKLFKFKVIRVLRFRSWNARRKFTKNRKHIKNIQRPTLPDGTKLIKFPILANAGEGSTNPRGRKEWIMNPNGKSFVCILHEYVQHALKTQPTYEFKELQNAATPYSATVSVNNLKYGTGYGTSKKQAKSEAARETLEILIPDVKDKITGNNKDQKSGTAKKAQSDLSVFDDIRIEDPRVTEFCNKTTEPSPNAILLTCLQRNYGSDVQISQEINRTANNKNEFTMTVGKHTAKVVCKNKREGKQLASQAILQILHPHIQTWGSLLRLYGNNSIKTFKEKKLEEQEITVLQSKAAVNQPNYAILDKLKSEMLKLCAKQESVLTMGTFVPPSDVDLPTSSGSNLNNVEL
Protein: Granulocyte colony-stimulating factor (F7FGY7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MAQLSAQGRMKLMALQLLLWHSALWSGQEAIPLLTVSSLPPSLPLPRSFLLKSLEQVRKIQARNTELLEQLCATYKLCHPEELVLFGHSLGIPKASLSSCSSQALQQTKCLSQLHSGLFLYQGLLQALAGISSELAPTLDMLHLDVDNFATTIWQQMESLGVAPTVQPTQSTMPIFTSAFQRRAGGVLVTSYLQSFLETAHHALHHLA
Protein: T-box transcription factor TBX18 (T-box protein 18) (O95935)
Organism: Homo sapiens (Human)
Function: Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201, ECO:0000269|PubMed:26235987}.
Interaction partners:
- Short stature homeobox protein 2
- Homeobox protein Nkx-2.5
- Transcription factor 21
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
- Wilms tumor protein
- Insulin gene enhancer protein ISL-1
Sequence:
MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLNRYSTSLAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSSQVSAHMV
Protein: DNA repair RAD52-like protein 1, mitochondrial (Organellar DNA-binding protein 1) (Q9FVV7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant-specific single-stranded DNA-binding protein required for efficient heterologous recombination-dependent DNA repair in nuclear and mitochondrial compartments. Forms large nucleo-protein complexes with WHY2 in mitochondria. Binds ssDNA with high affinity, but with little sequence specificity. Involved in double-stranded DNA break repair. Involved in the hydrolytic splicing pathway in mitochondrion. Facilitates the excision of two cis-spliced group II introns, NAD1 intron 2 and NAD2 intron 1.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:22202891, ECO:0000269|PubMed:22762281, ECO:0000269|PubMed:26048959}. Nucleus {ECO:0000269|PubMed:22202891}.
Interaction partners:
- Nuclear intron maturase 1, mitochondrial
- Single-stranded DNA-binding protein WHY2, mitochondrial
- Protein WHAT'S THIS FACTOR 9
- RCC1 domain-containing protein RUG3, mitochondrial
- DNA repair protein recA homolog 2, mitochondrial
- Pentatricopeptide repeat-containing protein At1g06710
- DEAD-box ATP-dependent RNA helicase 53, mitochondrial
- Protein OSB1, mitochondrial
- Transcription termination factor MTERF15, mitochondrial
- DNA repair protein recA homolog 3, mitochondrial
Sequence:
MAGLGLRLKAAKWTLRSGSGAVSREWSSEMGKGVRRFSTETENDVPTSGISRPLAEILKELNKKVPDSVIRTRVEDGCSIKYIPWHIVNRIMNMHAPEWSGEVRSVTYSPDGNTVTVAYRVTLYGTDAEIFRESTGTTSVDDKGYGDAVQKAEAMAFRRACARFGLGLHLYHEDAL
Protein: Prolactin-releasing peptide (PrRP) (Prolactin-releasing hormone) [Cleaved into: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20] (P81278)
Organism: Rattus norvegicus (Rat)
Function: Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.
Subcellular location: Secreted.
Interaction partners:
- Prolactin-releasing peptide receptor
- Pro-FMRFamide-related neuropeptide FF
- Pro-FMRFamide-related neuropeptide VF
- Orexigenic neuropeptide QRFP
- Neuropeptide FF receptor 2
- Prolactin
- Neuropeptide FF receptor 1
Sequence:
MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG
Protein: Mitochondrial import inner membrane translocase subunit TIM44 (Inner membrane import site protein 45) (ISP45) (Membrane import machinery protein MIM44) (Mitochondrial protein import protein 1) (Q01852)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 and its co-chaperone (MGE1) to drive protein translocation into the matrix using ATP as an energy source.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:18426906}; Peripheral membrane protein {ECO:0000269|PubMed:18426906}.
Interaction partners:
- Import motor subunit, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM14
- Mitochondrial import inner membrane translocase subunit TIM16
- GrpE protein homolog
- Mitochondrial import inner membrane translocase subunit TIM23
- Mitochondrial import inner membrane translocase subunit TIM17
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit TIM21
- Presequence translocated-associated motor subunit PAM17
- Mitochondrial DnaJ homolog 2
Sequence:
MHRSTFIRTSGTSSRTLTARYRSQYTGLLVARVLFSTSTTRAQGGNPRSPLQIFRDTFKKEWEKSQELQENIKTLQDASGKLGESEAYKKAREAYLKAQRGSTIVGKTLKKTGETMEHIATKAWESELGKNTRKAAAATAKKLDESFEPVRQTKIYKEVSEVIDDGESSRYGGFITKEQRRLKRERDLASGKRHRAVKSNEDAGTAVVATNIESKESFGKKVEDFKEKTVVGRSIQSLKNKLWDESENPLIVVMRKITNKVGGFFAETESSRVYSQFKLMDPTFSNESFTRHLREYIVPEILEAYVKGDVKVLKKWFSEAPFNVYAAQQKIFKEQDVYADGRILDIRGVEIVSAKLLAPQDIPVLVVGCRAQEINLYRKKKTGEIAAGDEANILMSSYAMVFTRDPEQIDDDETEGWKILEFVRGGSRQFT
Protein: Intraflagellar transport protein 57/55 (Q389K8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138}.
Interaction partners:
- C2H2-type domain-containing protein
- Intraflagellar transport protein 80
- Intraflagellar transport protein A1
- Intraflagellar transport protein component, putative
- Intraflagellar transport protein IFT88, putative
- IFT80/172/WDR35 TPR domain-containing protein
- Uncharacterized protein
- Intraflagellar transport protein 56 homolog
- Intraflagellar transport
- Intraflagellar transport protein 22
Sequence:
MSEETQPQSTEPKGSGSGVIIDDGTMDDLIDKLRILRYETEFCPRVKPPFKPLSKYYFSGPSTIDNPNAQFYYFTSLCSWLMGLSGRNFEPPGQFDDPNATATNILMELRGMNITAPNLAPNRLRQASGEAVLTVLSLLADHAILSKGLSIRAIDYSNIEKFDELEGATDGDENYGIGDEVEDNVMIDSDDDDELYVRAVGGKSGKEDTGIPVESEINADEWNLEVERVGPLLHVKSEAIQDWRSRIENAAILLKAVEKMYPEVRQMLQRMSDDLEKSKDRIQKREQTLAQQFSDQVEDYRVKLRELNSSQDAANIASQSVQQLSAELNQVSGLLDQVKRDIEEREAKLSDTSPLMQVKDAAVKVRAEIKQMSLRIGILQHTVLHYVMKQTKAKREGTANTSGGDEWEETDYM
Protein: Dynein axonemal intermediate chain 3 (Testis development protein NYD-SP29) (WD repeat-containing protein 63) (Q8IWG1)
Organism: Homo sapiens (Human)
Function: Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization. Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (By similarity). May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:32128961}.
Interaction partners:
- Dynein axonemal intermediate chain 4
- Dynein axonemal heavy chain 1
- Dynein axonemal heavy chain 2
- Dynein axonemal heavy chain 5
- Dynein axonemal heavy chain 17
- Dynein axonemal heavy chain 8
- Thioredoxin domain-containing protein 3
- Dynein axonemal heavy chain 7
- Dynein axonemal intermediate chain 7
- Dynein axonemal heavy chain 3
Sequence:
MAPKQKKKTSRGKKRLKPVLAASEDMEPVNMESMGHPEIYPLVLTTKTQEIFNCRIDEDVTDEQPYKLINKEDIFEDLRNRAAVSDFHPVKKIVQEYPGNELLLVYDKDFKYGLNFYLIATEEGKENYLNPPEVPEEQEEYKEHIPEDVYIYKPPVSKPWVSLGSEKEIEEESVTESTKQITYMISRKRSEFGAPIKFSDQNASSVKDAYIECTAYPDKNFTLKQLEKDVGMQVIPQIKDISTQTKWTYPKNATTQYYPREFSEEEKETLKQSKPLVDFLNNASISVEIALQQNEIMNTFIDDWKYLAEEEGTFGDKTDTHLKEYQSFTDLHSPTEKMITCVSWHPTIYGLIAVSVAVRLSFEDRVHFSGKLLLQPSLILFWSFSDPIHPQLMLESPDDIFCFKFCPSDPNIIAGGCINGQIVMWDITAHADRIENIKAGGSRSKRATLKPMFLLEPESNKEAMYIRHCAVSSIENGHKKVITDIHWLSDTFEINRMGSVFENRSGICCQLVTCSADCTICFWDIRPQKPLTPQTTEKKKEESIEIPFDVPSTFLHLDLSWKPLTKVRLSKGETSLDHCPTKISLNEDHLLCKTQDKMLAQSKTEKAEEMNPYHNLESGMANLLKPIDDFCTKFFVGTEEGEVIYTDWKMEKDPETGRLMSKKPVSHHTIHDGTVHTIQRSPFYNDIILTVGGWNVAIWKEGVMTGPLLQSCCAPKRYTSGHWSLTRPGVFYIGREDGYIDIWDLLEKTHEPAQSQNICITMITYIKPWIFSSKQQFIATADYYGTLHILEIPWTLSRPSTNEMASVNHYFEREVKHLEYVEQRKKIREQEKKEMELEMAKKKVKTYQKSKEQMQAELKMDYESYLELEKTVLINLGLIKVTEKGSYMEVM
Protein: Protein SCAI (Suppressor of cancer cell invasion protein) (Q8C8N2)
Organism: Mus musculus (Mouse)
Function: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000269|PubMed:19350017}. Cytoplasm {ECO:0000269|PubMed:19350017}. Note=Nuclear localization is required for inhibition of MRTFA.
Interaction partners:
Sequence:
MVRGARQSQQPRSRLAPRLSGTVEKPPRKRKSRTEFTLKETMSSGGAEDDIPQGERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLAETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGIQEPADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDGEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIVVDSSNSVAYKNFTNLFGQPLVCLLSPTAYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFVFCSATMRMHKAFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNIFFENSMDDY
Protein: Fatty acyl CoA synthetase 3 (EC 6.2.1.3) (Q9U402)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MGGCVISVMDYMNNRSEVENEHVKKFRALGKVAVPVPGSETSDCSPIYRLVTDDGKDIEEVRREWYEGECLPQRFAALCKRQPKQRALAYRPVDRVEKAVIKDLHTGTEKTVNVTHFKETKYLDYGTFWDYIESFGRGLVELGISPNSRVAIYEETRWEWLATIYGIWSQNMVATTVYANLGEDALAYALRETGCKGIICNAKNVSVVIKFMSEGITPSAPIIYNGSLPASVDQEACHLVSWEEVVKLGREARDRLPLNNSGRADDLALIMYTSGTTGDPKGVIHTHGSLMSGVHALDHRLNEVMGCHVKGETYCAYLPLAHILELGVVNIFIARGALICFGSPFTLTDLTARPRGDLAEYNPSLLIGVPRIYDTLKKAIQAKLPAPGTFKRRAFDHAFQSRLRAFKDGKDSPYWDAKVFAATRAVLGKGIRIALSGGGPLSTATQDFVNVVLARTIQGWGLTETVCVGGVQFTGDIETGAVGPPLLSEEVKLLDVEGYKHTDEPDPRGEILLRGPFLFKGYYKQEELTKEVLDEDGWFHTGDVGSIDPNGTLRIIGRVKALAKNVLGEYVAMEALESMYAHNSLSMPNGVCVLVHPDRPYICALVLTDEAKVVAFTREHGLKGKYPEVLQDPEFQKKATASFQETARASDRQKFEIVRHVRLLSDEWTPENGALTAVGKLKRRVIDERYTDIIAPLFVEEC
Protein: 4'-phosphopantetheinyl transferase domain-containing protein (Q552R4)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- holo-[acyl-carrier-protein] synthase
- Nuclear pore protein
- Uncharacterized protein
- Dephospho-CoA kinase
- Malonyl-CoA:ACP transacylase
- Probable polyketide synthase 2
- Malonyl-CoA:ACP transacylase
- Malonyl-CoA:ACP transacylase
- Probable polyketide synthase 16
- Acyl carrier protein, mitochondrial
Sequence:
MNKIFGIGNDIVKISRLESSFKRHGDKFLKRAFNEVEISIFKSLNPTASITESIDDNDNSELNNNNNNNNNNNNNNNNRGFEYLAGRWAAKESIYKAIGNQDRSKLNFQNIQILNESNGRPYVNLLETTESYFKELGINKIHLAISHDTDYAISNVILESNESTKN
Protein: GH11150p (TFIIE large subunit) (Transcription factor IIEalpha) (O96880)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Transcription initiation factor IIE subunit beta
- Transcription initiation factor IIB
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 4
- General transcription and DNA repair factor IIH helicase subunit XPD
- DNA-directed RNA polymerase II subunit RPB1
- Cyclin-H
- CDK-activating kinase assembly factor MAT1
- General transcription factor IIH subunit
Sequence:
MSSTSTAAANAAPAKTEVRYVTEVPSSLKQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLRFEKKQLRARITTLRTDKFIQIRLKMETGPDGKAQKVNYYFINYKTFVNVVKYKLDLMRKRMETEERDATSRASFKCSSCSKTFTDLEADQLFDMATLEFRCTFCGSSVEEDSAAMPKKDSRLMLAHFNEQLQPLYDLLREVEGIKLAPEVLEPEPVDIDTIRGLNKPNATRPDGMAWSGEATRNQGFAVEETRVDVTIGGDDTSDAVIERKSRPIWMTESTVITDTDAADGAADAVQTASGSGHRNRKENEDIMSVLLQHEKQPGQKEPHMKGMRVGSSNANSSDSSDDEKDIENSKIPDVDFDNYINSDSAEEDDDVPTVLVAGRPHPLDQLDDNLIAQMTPQEKENYIHVYQQHYSHIFE
Protein: Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2) (GABAAR subunit beta-2) (P63137)
Organism: Mus musculus (Mouse)
Function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity. Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:P63138}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P47870}. Cell membrane {ECO:0000250|UniProtKB:P63138}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P47870}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P63138}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit gamma-2
- Gamma-aminobutyric acid receptor subunit alpha-2
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid receptor subunit beta-1
- Gamma-aminobutyric acid receptor subunit beta-3
- Gamma-aminobutyric acid type B receptor subunit 1
- Gamma-aminobutyric acid receptor subunit gamma-1
- Gamma-aminobutyric acid receptor subunit epsilon
- Gamma-aminobutyric acid receptor subunit gamma-3
Sequence:
MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAANANNEKMRLDVNKMFYKDIKQNGTQYRSLWDPTGDLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
Protein: Meiotically up-regulated gene 64 protein (Q10253)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
METFKTHITGQFNATVSSITPFAKKTTHYLRTKIGSRVEELSLPEDYVELEQQVDSLKEAYNLVLPIVETVEVDGYDYPTNFRDSITDFGKTVSGKVRNLGNLTPLEQTPLASVGKNLEEKEAAAKPSRTLYNAISRAASEATTKMGAGNPLSSAFGQISVLEEKVGNLQGERDSAISKNFCEQVRAVLYPRFAEAHRVKADVQDKRLQLEMAKLDVESAKPENLEHCKSAVRSAEDELNGAIEHAKILYEQILNKDYNTDLLRSIIKNQLKFHQDAAAALSDITI
Protein: Lysophosphatidylcholine acyltransferase (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (Acyltransferase-like 2) (Q0KHU5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acetyltransferase which mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (By similarity). Has a calcium-independent activity (By similarity). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity). Involved in the regulation of lipid droplet number and size.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8NF37}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8NF37}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8NF37}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8NF37}. Lipid droplet {ECO:0000269|PubMed:25491198}.
Interaction partners:
- Lysophospholipid acyltransferase 5
- Probable cardiolipin synthase
- Phospholipase
- Uncharacterized protein, isoform A
- BcDNA.GH02384
- phospholipase A2
- Phospholipase A2
- Platelet-activating factor acetylhydrolase IB subunit beta homolog
- Neuropathy target esterase sws
- Phosphatidylserine synthase
Sequence:
MTTSTIKPTGGDEVPPAGVVGNVADVGVAASLTKRDSEEDTWASKGYNYINPFVHRIEIDSHIEVAKIYVLTVLLLPIRVVGCVLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVDSILVVASGPPSIVAKRETADIPLLGKIINYAQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKPGAFYPGVPVQPVLLKYPNKYDTFTWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDEVADANLYANNVREVMAKALGVPTSDYSFEDVIVMSRARDMKIPFPGDIVEIERTIEKLGLNESQRDAELCKGFLRLSNTDRLDIITFGELLQVDLKNTDLHKLFALLDHRRSGTVSLKSFLLCSLFCKLKNSDLLTFLRALIHLYSESSQQIDRESFVRLMRHAGGKLNEQKAQALFYALDTDNLGYVSFDSFVELTEKQKSSYKFLYHKSEHIRRPKAVVTTAEN
Protein: Fatty acid amide hydrolase (EC 3.5.1.-) (N-acylethanolamine amidohydrolase) (G7ISB0)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Catalyzes the hydrolysis of bioactive endogenous fatty acid amides to their corresponding acids. The hydrolysis of endogenous amidated lipids terminates their participation as lipid mediators in various signaling systems (Probable). Converts a wide range of N-acylethanolamines (NAEs) to their corresponding free fatty acids and ethanolamine.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q7XJJ7}. Cell membrane {ECO:0000250|UniProtKB:Q7XJJ7}.
Interaction partners:
Sequence:
MGKKRVMVPAKDVDLSSIKYEPEIVQAPHLTGFWFRFFVRLIEAPLIGPFLLTMLKKENKIDQLLRNTVFPEEPMFKPEYPPQEKEHSVVELDEDGRPEGRVESALNCLPHYDPAKLWENSSATFRYWKIRDYAYAYQSRKVTPSMVAESIISMIEENGIDKPPTPLLLSFDAAEVRKQAAASTQRFESGNPLSILDGIFIAIKDDIDCHPHPSTGGSTWMHEVRDVKKDAVCVSRLRSCGVIFIGKTNMHEFGMGTTGNNSNYGTARNPHAPDRYTGGSSSGPAAIVASGLCSAALGTDGGGSVRIPSSLCGVVGLKINYGRTSMEGSLCDSGTVEVIGPIASTVEDAMLVYAAMLGASPANRISMKPSTPCLPTLSSDDDTDALRSLRIGIYTPWFNNVHSTEVSDKCEDALNLLSKAHGCEVVEVVIPEIVEMRTAHLVSIGSECLSSLNPDIEDGKGVKLSYDTRTSLALFQSFTAADYVAAQCIRRRIMHYFMEIFKKVDVIVTPTTGMTAPRIPPSALKSGETDMPTTGYLMRFVVPANLLGLPAISVPVGYDKEGLPIGLQVIGRPWAEATILRVAAAVEKLCGESKRRPVTYYDVLGAN
Protein: Serine/threonine kinase 24 (Q5JV98)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
ADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKLKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGTSSH
Protein: Insulin growth factor-like family member 1 (Q6UW32)
Organism: Homo sapiens (Human)
Function: Probable ligand of the IGFLR1 cell membrane receptor.
Subcellular location: Secreted {ECO:0000269|PubMed:16890402, ECO:0000269|PubMed:21454693}.
Interaction partners:
- IGF-like family receptor 1
Sequence:
MAPRGCIVAVFAIFCISRLLCSHGAPVAPMTPYLMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCGNCTFRVCFEQCCPWTFMVKLINQNCDSARTSDDRLCRSVS
Protein: Rad21/Rec8-like protein C-terminal eukaryotic domain-containing protein (Q19232)
Organism: Caenorhabditis elegans
Interaction partners:
- Meiotic recombination protein rec-8
- HORMA domain-containing protein
- HORMA domain-containing protein
- Structural maintenance of chromosomes protein 3
- Separin homolog sep-1
- Wings apart-like protein homolog 1
- separase
- HORMA domain-containing protein
- Long arms of the bivalent protein 1
- DNA repair protein RAD51 homolog
Sequence:
MVISIDVPLKASEEATVKFLLGIVFGSHKKLGLQSNRRECFRHDVLQASKLIQWILSNERKNRRSLSIACNLVYGNTIVLSTQVARLLQDAIRAREIVAFTSYLAEEDERKRKTREQMEGDNSKTPKKKRRTMVEEFPLTPTPISVALKQNITMPDVLSLHKNDQINVEDDLAAPTMEQLEMMYGMLESENRNTAIDLTFIDRYSSNDCRQNVHNLNLETDFQRPSDDFIRSQLMTPTKSIPQEEEFQPATHLKEMLLFRQLPITLDETERRRSMEEEMEEARNSGINTEFIPPQQMDVPRLVSENMDLDDEVSIPIRIPKVPLSATKKQTSENEGAEEGINYKIPLREMHHIMEDYSSLHFKDPEPLYRKTSKVMNLKELLNPIPYFLRKGCNTDMWDLFKVKTRKFDSTIGHDVSDTEEEDEDEETERRNRLKAELEPLETIDLSQMKFMTTPLKDKSPILTPVHRPEEIEFREELELPRFEQFEPMNVNPISPKMEEPALFEDNWNSKPTWSNTSSENIADALTIRGNIIRQLDDKSPFEVTLDSMIPVAATSRREAARTFYTVLELLKERKIKATQRAPYENIDLLLSTDDSEDIDDLAMADF
Protein: Arabinogalactan protein 14 (AtAGP14) (Arabinogalactan peptide 14) (AG-peptide 14) (Q9LVC0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death (Probable). Involved in the regulation of root hair elongation.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:15322080}.
Interaction partners:
- Arabinogalactan protein 22
- Classical arabinogalactan protein 7
- Classical arabinogalactan protein 2
- Classical arabinogalactan protein 3
- Classical arabinogalactan protein 9
- Classical arabinogalactan protein 5
- Lysine-rich arabinogalactan protein 19
- Classical arabinogalactan protein 25
- Arabinogalactan protein 16
- Filament-like protein
Sequence:
MEAMKMKLYVVVLVAVIAFSTVHQTVAAVDAPAPSPTSDASSFIPTFFASVAVMAFGFFF