wanglab/gogpt-training-data huggingface dataset:
Protein: BHLH transcription factor (Os02g0116600 protein) (cDNA clone:001-035-A10, full insert sequence) (cDNA clone:006-303-B03, full insert sequence) (cDNA clone:J033129B02, full insert sequence) (Q6ZGM4)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MDGGGDPVDEFLIGGGGEDGDLGVFCDGVPTLPCDGGLGIDDVSGDTCCLDQSVLGKRGRDESSSSGPKSKACREKIRRDRLNDRFLELSSVINPDKQAKLDKANILSDAARLLAELRGEAEKLKESNEKLRETIKDLKVEKNELRDEKVTLKAEKERLEQQVKALSVAPTGFVPHLPHPAAFHPAAFPPFIPPYQALGNKNAPTPAAFQGMAMWQWLPPTAVDTTQDPKLWPPNA
Protein: ESCRT-III complex subunit did4 (Vacuolar protein-sorting-associated protein 2) (O14177)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Acts a component of the ESCRT-III complex, which appears to be critical for late steps in MVB sorting, such as membrane invagination and final cargo sorting and recruitment of late-acting components of the sorting machinery. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complex assemblies (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Vacuolar protein sorting-associated protein 24
- Vacuolar protein-sorting-associated protein 46
- Vacuolar-sorting protein snf7
- Vacuolar protein sorting-associated protein 20
- Suppressor protein of bem1/bed5 double mutants
- Uncharacterized protein C162.06c
- Vacuolar protein-sorting-associated protein 25
- Vacuolar protein-sorting-associated protein 36
- Vacuolar protein sorting-associated protein ist1
- Vacuolar protein sorting-associated protein 27
Sequence:
MGLTSWLFGGGKSPQEQLRAHQRSLGRAERELDRERTKLDQRERALIQEIKGSAKAGNTGAARIQARDLMRLRNSRKKMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMARITQQFERENEIMEQRQEMIDENMDDALEEDDEEEADELVNKVLDEIGVDLSQGLPDAATQIGTVPELKTEDNLQARLDELAKR
Protein: Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1) (Q01167)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis and autophagy (By similarity). Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription activator or repressor, depending on the context. Together with FOXK1, acts as a key regulator of metabolic reprogramming towards aerobic glycolysis, a process in which glucose is converted to lactate in the presence of oxygen (By similarity). Acts by promoting expression of enzymes for glycolysis (such as hexokinase-2 (HK2), phosphofructokinase, pyruvate kinase (PKLR) and lactate dehydrogenase), while suppressing further oxidation of pyruvate in the mitochondria by up-regulating pyruvate dehydrogenase kinases PDK1 and PDK4 (By similarity). Probably plays a role in gluconeogenesis during overnight fasting, when lactate from white adipose tissue and muscle is the main substrate (By similarity). Together with FOXK1, acts as a negative regulator of autophagy in skeletal muscle: in response to starvation, enters the nucleus, binds the promoters of autophagy genes and represses their expression, preventing proteolysis of skeletal muscle proteins (By similarity). In addition to the 5'-GTAAACA-3' DNA motif, also binds the 5'-TGANTCA-3' palindromic DNA motif, and co-associates with JUN/AP-1 to activate transcription. Also able to bind to a minimal DNA heteroduplex containing a G/T-mismatch with 5'-TRT[G/T]NB-3' sequence. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter. Positively regulates WNT/beta-catenin signaling by translocating DVL proteins into the nucleus. Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements.
Subcellular location: Nucleus {ECO:0000269|PubMed:20810654, ECO:0000269|PubMed:24748658, ECO:0000269|PubMed:25805136}. Cytoplasm {ECO:0000250|UniProtKB:Q3UCQ1}.
Interaction partners:
- Putative Polycomb group protein ASXL2
- Paired amphipathic helix protein Sin3a
- Polycomb group protein ASXL1
- Ubiquitin carboxyl-terminal hydrolase BAP1
- Host cell factor 1
- AOF1 protein
- UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
- Histone-binding protein RBBP7
- Transcriptional repressor protein YY1
- Nuclear receptor corepressor 2
Sequence:
MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN
Protein: Putative RNA-binding protein YbcJ (P0AAS7)
Organism: Escherichia coli (strain K12)
Function: Its structure and the presence of conserved basic residues indicates that it probably binds RNA.
Interaction partners:
- Uncharacterized protein YibL
- Bifunctional protein FolD
- RNA-binding protein YhbY
- ATP-dependent RNA helicase SrmB
- Pole-localizer protein TmaR
Sequence:
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
Protein: 2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4) (Q08DF7)
Organism: Bos taurus (Bovine)
Function: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:Q6L8Q7}.
Interaction partners:
- Leucine-rich PPR motif-containing protein, mitochondrial
- SRA stem-loop-interacting RNA-binding protein
- Probable ATP-dependent RNA helicase DDX6
- Ribonuclease L
Sequence:
MWRLPGVRAALRGVRTAVERRSRTEAASETSVGAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRALSRIATNALKGHAKVAAAKKSRKNRPNAGSGVACAGPGPEPAAACEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLGVEFGDPTGSLFRWYKETKPRAAEPEGGGPSSSSPSSPSPGWTETGVDERVYTPSNADIGLRLKLHCTPGNGQRFGPSRELESVCPVEAGPGTCTFDHRHLYTKKVTDDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRCVFTDSLMPALEAFGLEGVFRIKQHEGLATFYRKSKFSLLSQHDIAFHEALQSDPLHKELLEKLALYPSAQERVLQRSSVVQVSVLQSTKDSSKKICVANTHLYWHPKGGYIRLIQMAVALAHIRHVSCDLYPGIPVIFCGDFNSTPSTGMYHFVINGSIAEDHEDWTSNGEEERCNMSLSHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLHALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK
Protein: Protein REVEILLE 8 (MYB-like transcription factor RVE8) (Protein LHY-CCA1-like 5) (Q8RWU3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator of evening element (EE)-containing clock-controlled genes. Forms a negative feedback loop with APRR5. Regulates the pattern of histone H3 acetylation of the TOC1 promoter.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
- Protein LNK1
- Protein LNK2
- Two-component response regulator-like APRR1
- Two-component response regulator-like APRR5
- Two-component response regulator-like APRR9
- Transcription factor LUX
- Protein EARLY FLOWERING 4
- Two-component response regulator-like APRR7
- WD repeat-containing protein LWD1
- Protein EARLY FLOWERING 3
Sequence:
MSSSPSRNPTNAEAPPPPPTSTDAVAEGSSKKVRKPYTITKSRESWTEEEHDKFLEALQLFDRDWKKIEDFVGSKTVIQIRSHAQKYFLKVQKNGTLAHVPPPRPKRKAAHPYPQKASKNAQMPLQVSTSFTTTRNGDMPGYASWDDASMLLNRVISPQHELATLRGAEADIGSKGLLNVSSPSTSGMGSSSRTVSGSEIVRKAKQPPVLHGVPDFAEVYNFIGSVFDPETRGHVEKLKEMDPINFETVLLLMRNLTVNLSNPDLESTRKVLLSYDNVTTELPSVVSLVKNSTSDKSA
Protein: Probable serine/threonine-protein kinase roco8 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 8) (Q54M77)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Uncharacterized protein
- SAP DNA-binding domain-containing protein
- Probable serine/threonine-protein kinase qkgA
- Probable serine/threonine-protein kinase roco5
- Probable serine/threonine-protein kinase roco6
- Tubulin beta chain
- Latrophilin receptor-like protein A
- Probable serine/threonine-protein kinase roco11
- Uncharacterized protein
- Tubulin alpha chain
Sequence:
MFDYNQLNKLKDKIQSSDGLQIKDRTYLYKTYRSVFVGYECVDWIFGNCPDIKTREDAIKLGQTLFDAGIICNVTSGADPIFKDDYIFYQFDNNKNNNNINNNNNNATSTATTATAPITPVSTKIGSIGKSSSKSSTAVDKMNNNNNNNNNNNNNNNNNNNNNSNNSNSNNNSSRRTSSVPPPVLVTASLSSSTSSSSSSTTSTSSSLASTNTNSNSTYNSNSFNKKHHRYSINELSKVVLEDLNTVTLVKDELIQLSQELMNGDKGLKLQKKKKGAAGTTISCFSGSQLIDWLVKKLEVTRKESIQIASALMHLNIFIEVGTIFNSSNNNNNNNNGGGGVMSSTLSTTIPSSISLQQLSNQSQSNSNSSSSSSILNLSFTAPISISSTTATMSSSLSLSTTAATTTTTTTSSSLLNNSSSGSGFLVPTLPASVLNSSSNSNNQLYSSSPLSLSTSSIPAFDNRIVEDCGNVFYEFLTKPEAIINHVAMRRLDDLCLTHKCISIIPTTIINTSKFLRIIDLSFNQLSESNQLESIATLYNLESCNLSHNQLSTLPSSFSRLELLTKLILSHNCFQVIPNVVFQLSNLEELSLAANQLSSISESIGSLKSLEKLDLSFNKQINKIPKELGLLVRLKSLNVLGSNKINELPSFLSTLPLLEQLDFSRDIIKSPPKEITSKGFTHIIGYLKDLFEGTETLSHIKLMVLGSEKTGRSSLVKALTKSQTKSLSRQSANFLKKVTSSEVSLNDPIEIIQLKLDLPPEQQNGIMTSSSNLNLSTGTLPPPTQLSSSTSELKPQRKDSFGSSMTTPEKKRPTKRNVKLMIYDFRMPSIDVYYHTHQFFLSERAFYLVTYDINKDLSHSGLEFWVESIKKKAPNAPIYIVATHIDTFNQYGGDILVPLNEIDQYLTQRSLEVTGVIGVSSTTLRNIDLLKNEIIQTLLNQSNNNNNNNNNNNYNNNKQSNSISTTNWLNERIPSIYITLETNLQEEAKKRPIVTWDEYQNIAKLSNFTTSSYEKLVRATNTLNRWGSIIWFEDSKSSLKDFVILDPQWFSDCFYKLLLAKHSFINSDGILLLSNLKNIWKPNIVPEQFHIKLLKLLERYQILYTLKNNSNLQQLQQQQQQQKSFGNLSKENSLNSMSYSIESRSSSSPLPTVVTLSAEISSSPSLSLSNSSQSVFTNPNNNNNNKSEQQQQQQQQQQQPQPISTSPKLLRNSLKNLKSIENNSSSLSNNSILNSNSNSSGNLLQNGSYISFNRIIIPCLLPNGKPSHLASLWDTWSGEDEHQIGRYYQFRNISAKNCFERVMVRFLYMMEPIVYWSTGILFRKTQTYRENIKDSMSSCGTLVEFDTVTQQLQIRVRGHEFDACAKLFQIVLENVDTILKDYQINQSQTYIPCSCSCECRDLPHLFPIDLIEETFGKGESHTKCPITMKLVSLCKISPDITLSSVSSNKKVSKEDLIYQEEIGVGGFSRVYKGIYKNNTVAIKQFNFERMDLIDSTSFNNLNSLTISPSNSSLSISLSSSTSSLSPPIVNNNNNNNNLNNNLNNLNNNNKLYIQQQQQTQQNQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNQQQPKILQRNLSTSSLSSNSSQGEDSMNQISSGKLNAINEFRREVWLMSGLSHSNIVLMKGFCFEPYAIVMEYMDIGSLSSFLKKKKEDGQVLDWQMLLKIVTDIASGMAFLHNITPPLVHRDLKSPNILLASHPTNPNEISAKVSDFGLSRSIVQNFSSKVVDNPTWQSPEVLKGMEYNEKSDIYSFGMILWECYHLELPFDEFDFKFMSTLEDNILSGLRPSINQNCNRMYSSLITKCWNADPNLRPSFNSILKTLNEIKDSTINSK
Protein: Probable RNA exonuclease C9B6.11c (EC 3.1.-.-) (Q9Y7M8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MYTCPKTCTLTLKFFIDRFHTDYRLSKLAISFFDQKKNKMADSIPVKKKGSAKGPPSFVTPEYIEKQRQKKLEKMAKKAARKPIAPPSNAPPEFNTDFIKREMLSIPNYAPFETEKSALDITIMTYNVLAQTNIRRSMFPHSGEALKWKNRSRMLANELTYYSPTLGCMQEVDAEFVPNFYKKLLGGLGYELHFIKGEGKTHGIMIFWKSSLFKKVQDLTIYYDDHDELPGRMNTKNIGCCVRLERVDDPSRGLFLATTHLFWHPYGSYERLRQGAILVKEVNKMAQSHPSWPVFIAGDFNTEPFDTNFPALTTRPLSICQRATDIIERSMNYVFGESELEEKNASTKTENDSNEDDKEECQSSSTSSVPESTASTPKKRILHVQNDYVPHYRSFYQQHEQNPVLFSLYSVGYKLVHPENAKNTFDHPAFTNWAHAYQGHLDYIFVMNRDTSLQTPENQVVEGIKLKALLRVPLPSEMKEAEPLEGRYPSDHVALMANVQIV
Protein: heme oxygenase (biliverdin-producing) (EC 1.14.14.18) (D6QXI6)
Organism: Triticum aestivum (Wheat)
Subcellular location: Plastid, chloroplast {ECO:0000256|ARBA:ARBA00004229}.
Interaction partners:
Sequence:
MAPAAASASASLAATAPHHALAPPRASVSVAAAGRNSGLSVSVGVRPVPGISVVNSQRRRMVAAAAATEMAPAARGEGGGKPFMDEMRAVAMRLHTKDQAREGEKEPQAPPVARWEPTVEGYLRFLVDSKLVFQTLEDIVDRAAVPWYAEFRNTGLERSEPLKKDLEWFTEQGHTIPEPSAAGTAYASYLEELSEKDPQAFICHFYNVYFAHTAGGRMIGKKVAEKILNKKELEFYKWEGTLSQLLQNVRTTLNQVASSWSREEKDHCLEETEKSFAYSGDLLRQIFT
Protein: Unconventional myosin-VI (Unconventional myosin-6) (D4A5I9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection, microvillus {ECO:0000256|ARBA:ARBA00004105}. Cell projection, ruffle membrane {ECO:0000256|ARBA:ARBA00004632}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane, clathrin-coated pit {ECO:0000256|ARBA:ARBA00004600}.
Interaction partners:
- Disabled homolog 2
- PDZ domain-containing protein GIPC1
- PDZ domain-containing protein GIPC2
- Target of myb1 homolog
- Serine/threonine-protein kinase PAK 1
- Serine/threonine-protein kinase PAK 3
- Clathrin light chain A
- Espin
- Actin, cytoplasmic 2
- Similar to PDZ-domain protein Gipc3
Sequence:
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNVKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSDTIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYVKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAPSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANSARDALAKTVYSHLFDHVVDRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEVKLVGILDILDEENRLPQPSDQHFTSVVHQKHKDHFRLTIPRKSKLAVHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRALFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPEKLARLDPRLFCKALFKALGLNEVDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNLWLVCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSALKDGKPEVNRQIKDLEISIDALMAKIKSTMMTREQIQKEYDALVKSSEDLLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEQRRRKEEEERRMKLEMEVKRKQEEEERKKREDDEKRIQAEVEAQLARQREEESQQQAVLAQECRDRELALRIAQNESELISDEAQGDTALRSSSSCPASSKTNGTRPQMTPEQMAKEMSDILSRGPAVQATKAAAGTKKHDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYAQQNPAAQLPARQQEIEMNRQQRFFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQSAIESRQARPTYATAMLQNLLK
Protein: RNA helicase (EC 3.6.4.13) (A0A060VZM9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Fanconi anemia group G protein
- RNA helicase
- E3 ubiquitin-protein ligase FANCL
- FA complementation group F
- FA complementation group B
- RLR CTR domain-containing protein
- RecQ mediated genome instability 2
- Toprim domain-containing protein
- Toprim domain-containing protein
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MAADKDNTTNISLIEDFRPRLRKLIEIEFVLDHLNFLDNDNKDLIRTKARKESNLKAVDLLIDTIIRIRPLPKGWFREFVDALSAGGCKHAATYVEDSPPCPALEAENDNCVRLIELLSPRLLGMKTTDVCWDCFSKGILTAEDREIILAECQNRGNMGGARELLRRIVRFPPGWFSTFLKALQVTEHNDLCKELTGESPGDNLIDEPGVLMAVNEAPGNVDPMVEEGPVEAAGKSFLPEQETLDSSVTSMHLDEPSEADSEIADLYSGTEEPMENGKPENSLDLSMSGCIAPAAESPPKAVIVLRDYQMDVARPALEGKNIIICLPTGSGKTRVAVYITKEHLDSRRKEGRPGKVVVLVNKVPLVEQHYSTEFWKFLKNKYKVERVSGDSQLKISFTDIVQKNDIVICTAQLLENYLERAHSGDDDGIKLSDLSLIVIDECHHTQKGGVYNHIMIRYLKQKHKNAKLKKEQKDTVAIPQILGLTASPGVGGAKKIEKAEEHILRICANLDAYKIMTGNLGENKKEPHKKIATAEERKRDVDFHEIIYIYIILMCKCIYVLTSDPFGDVLKGVMNAIHIHAELNPTCDLGTQNYEQWVVQKEQNAAKEENQKVRVCAEHLRQYNEALYLGKTIRMWDAFSFLDKYFDEELKKKVAPEDEEAIIKTDTERFLFTLFKDSKVKLQELAKLPQYENNSLAKLRTKILHEFTSREKARGIIFTKTRRSAIALAQWVQENSKFEEVGVKACHVIGGGGQSVVKPMTAAEQRDVLNKFQNAEINLLIATTVAEEGLDIAACNFVIRYELVTNEIAMIQARGRGRAEDSSYTLVAGEGSGVAERESVNEYREKMMSKAIDKVKKLDQEEYEKRIKEFQIQAIMEERVRTTKKKQKGMKKESPSKVKFSCRSCNKPVCSGEDVEIIENMHRVNVTPQFKELFIQRENTSLVKRLLDYESNGFIACKDCGQRWGSMMLYRGIECPCLHVKNFLVTYDEKRKNVNKWSELGIQLPAFDYAEHARSVAESSEDEESM
Protein: Scarecrow-like protein 23 (AtSCL23) (GRAS family protein 28) (AtGRAS-28) (Q9FHZ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor involved in plant development.
Subcellular location: Nucleus {ECO:0000269|PubMed:18500650}.
Interaction partners:
- Defensin-like protein 232
- Protein S-acyltransferase 11
- Thiohydroximate-O-sulfate sulfur/sulfate-lyase
- Putative scarecrow-like protein 16
- Protein PAT1 homolog
- Thiohydroximate-O-sulfate sulfur/sulfate-lyase
- WAT1-related protein At5g45370
Sequence:
MTTKRIDRDLPSSDDPSSAKRRIEFPEETLENDGAAAIKLLSLLLQCAEYVATDHLREASTLLSEISEICSPFGSSPERVVAYFAQALQTRVISSYLSGACSPLSEKPLTVVQSQKIFSALQTYNSVSPLIKFSHFTANQAIFQALDGEDSVHIIDLDVMQGLQWPALFHILASRPRKLRSIRITGFGSSSDLLASTGRRLADFASSLNLPFEFHPIEGIIGNLIDPSQLATRQGEAVVVHWMQHRLYDVTGNNLETLEILRRLKPNLITVVEQELSYDDGGSFLGRFVEALHYYSALFDALGDGLGEESGERFTVEQIVLGTEIRNIVAHGGGRRKRMKWKEELSRVGFRPVSLRGNPATQAGLLLGMLPWNGYTLVEENGTLRLGWKDLSLLTASAWKSQPFD
Protein: Collagen alpha-2(VI) chain (Q02788)
Organism: Mus musculus (Mouse)
Function: Collagen VI acts as a cell-binding protein.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Recruited on membranes by CSPG4. {ECO:0000250}.
Interaction partners:
- Collagen alpha-1
- von Willebrand factor A domain-containing protein 1
- Collagen alpha-1
- Collagen alpha-2
- CD44 antigen
- Collagen alpha-1
- Platelet glycoprotein VI
- Collagen alpha-1
- Integrin alpha-5
- Collagen alpha-1
Sequence:
MTTIKMLQGPLSVLLIGGLLGVLHAQQQEAISPQEQEAVSPDISTTERNNNCPEKADCPVNVYFVLDTSESVAMQSPTDSLLYHMQQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFTKSLQGIRSFRRGTFTDCALANMTQQIRQHVGKGVVNFAVVITDGHVTGSPCGGIKMQAERAREEGIRLFAVAPNRNLNEQGLRDIANSPHELYRNNYATMRPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPHGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGSDGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGSRGPDGYPGEAGSPGERGDQGAKGDSGRPGRRGPPGDPGDKGSKGYQGNNGAPGSPGVKGGKGGPGPRGPKGEPGRRGDPGTKGGPGSDGPKGEKGDPGPEGPRGLAGEVGSKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGTPGEKGEPGPPGPEGGRGDFGLKGTPGRKGDKGEPADPGPPGEPGPRGPRGIPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFEAIRLDDERVNSLSSFKEAVKNLEWIAGGTWTPSALKFAYNQLIKESRRQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHETHESENLYSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPELPCQTELYVAQCTQRPVDIVFLLDGSERLGEQNFHKVRRFVEDVSRRLTLARRDDDPLNARMALLQYGSQNQQQVAFPLTYNVTTIHEALERATYLNSFSHVGTGIVHAINNVVRGARGGARRHAELSFVFLTDGVTGNDSLEESVHSMRKQNVVPTVVAVGGDVDMDVLTKISLGDRAAIFREKDFDSLAQPSFFDRFIRWIC
Protein: Glyoxysomal processing protease, glyoxysomal (AtDEG15) (EC 3.4.21.-) (DEG-protease) (Q8VZD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Trypsin-like serine endopeptidase involved in the processing of glyoxysomal higher molecular weight precursor. The dimeric form carries out the specific cleavages needed to remove PTS2-containing presequences, whereas the monomeric form degrades the removed presequences and misfolded proteins (Probable). Not required for degradation of glyoxylate cycle enzymes during seedling development.
Subcellular location: Peroxisome {ECO:0000269|PubMed:15333753, ECO:0000269|PubMed:18952862}.
Interaction partners:
- Protease Do-like 10, mitochondrial
- Putative Do-like 15 protein
- Protease Do-like 7
- Protease Do-like 5, chloroplastic
- Protease Do-like 8, chloroplastic
- Putative protease Do-like 14
- Peroxisome biogenesis protein 5
- Protease Do-like 9
- Putative protease Do-like 13
- Peroxisome biogenesis factor 10
Sequence:
MDVSKVVSFSRNFAVLVKVEGPDPKGLKMRKHAFHQYHSGNATLSASGILLPRDIFLSGEVAAKVLFEAGQDMALVLTVASVVEPFLTLGHRTSSSISQDPVKLIPGAMIEIMVEGQLKSEKEAPFWVPAQLLSLVDVPVSSAALQSLIEASSGSKDSGWDIGWSLVSAANGSQPSINIEHYSKPLMQLDEPHNANFMAKSATRMAILGVPLSLLGQPSMNFASSSSKGDTLVALGSPFGILSPVNFFNSVSTGSIANSYPSGSLKKSLMIADVRCLPGMEGAPVFAKNGHLIGILIRPLRQKNSGVEIQLVVPWGAITTACSHLLLEEPSVEGKASQWGSEVLSVKSDASIPAQVAIEKAMESVCLITVNDGVWASGIILNEHGLILTNAHLLEPWRYGKGGVYGEGFKPYVLGAEEFSSTGSKFWEQKSQTLPRKAPRNHYSSVGENIREYKHNFLQTGHRDIRVRLCHLDSWTWCPANVVYICKEQLDIALLQLEYVPGKLQPITANFSSPPLGTTAHVVGHGLFGPRCGLSPSICSGVVAKVVHAKRRLNTQSISQEVAEFPAMLETTAAVHPGGSGGAVLNSSGHMIGLVTSNARHGAGTVIPHLNFSIPCAVLAPIFKFAEDMQNTTILQTLDQPSEELSSIWALMPSLSPKTEQSLPNLPKLLKDGNNKQTKGSQFAKFIAETQDMFVKPTKLSRDVIPSKL
Protein: Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor) (P61328)
Organism: Homo sapiens (Human)
Function: Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Sodium channel protein type 5 subunit alpha
- C-Jun-amino-terminal kinase-interacting protein 2
- Calmodulin-1
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
Sequence:
MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST
Protein: Cytokinin dehydrogenase 4 (EC 1.5.99.12) (Cytokinin oxidase 4) (AtCKX4) (CKO 4) (Q9FUJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group.
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Adenylate isopentenyltransferase 5, chloroplastic
- Cytokinin hydroxylase
- Adenylate isopentenyltransferase 3, chloroplastic
- Histidine kinase 3
- Cytokinin hydroxylase
- Histidine kinase 4
- Histidine kinase 2
- Two-component response regulator ARR7
- Adenylate isopentenyltransferase 7, mitochondrial
- Two-component response regulator ARR6
Sequence:
MTNTLCLSLITLITLFISLTPTLIKSDEGIDVFLPISLNLTVLTDPFSISAASHDFGNITDENPGAVLCPSSTTEVARLLRFANGGFSYNKGSTSPASTFKVAARGQGHSLRGQASAPGGVVVNMTCLAMAAKPAAVVISADGTYADVAAGTMWVDVLKAAVDRGVSPVTWTDYLYLSVGGTLSNAGIGGQTFRHGPQISNVHELDVITGKGEMMTCSPKLNPELFYGVLGGLGQFGIITRARIALDHAPTRVKWSRILYSDFSAFKRDQERLISMTNDLGVDFLEGQLMMSNGFVDTSFFPLSDQTRVASLVNDHRIIYVLEVAKYYDRTTLPIIDQVIDTLSRTLGFAPGFMFVQDVPYFDFLNRVRNEEDKLRSLGLWEVPHPWLNIFVPGSRIQDFHDGVINGLLLNQTSTSGVTLFYPTNRNKWNNRMSTMTPDEDVFYVIGLLQSAGGSQNWQELENLNDKVIQFCENSGIKIKEYLMHYTRKEDWVKHFGPKWDDFLRKKIMFDPKRLLSPGQDIFN
Protein: Phenylalanine-specific permease (Phenylalanine:H(+) symporter PheP) (P24207)
Organism: Escherichia coli (strain K12)
Function: Permease that is involved in the active transport across the cytoplasmic membrane of phenylalanine. Can also transport tyrosine, but not tryptophan.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:8626334, ECO:0000269|PubMed:9791098}; Multi-pass membrane protein {ECO:0000269|PubMed:8626334}.
Interaction partners:
- Lactose permease
Sequence:
MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTRVSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRFRAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFMAFKTLRRK
Protein: Ferric enterobactin receptor PirA (Q9I527)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell outer membrane {ECO:0000255|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU01360}.
Interaction partners:
- Ferric enterobactin receptor
- Second ferric pyoverdine receptor FpvB
- Iron
- Probable tolQ-type transport protein
- Ferrienterobactin-binding periplasmic protein FepB
Sequence:
MYPQFRRGHLAAAVLFASSSLLGGQALAEDERLEELDERAESVVQLGDEVVLGTAEQELKQAPGVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDTRGDSNWVPPEEVERIEVLRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPLTEALSFRAYGSANKTDSDDTDINLGHTVNPSRTVAGREGVRNRDLSGMLSWQVTPDQVVDFEAGFSRQGNIYAGDTQNNNGTANTQGLADDGAETNRMYRENYAITHNGTWSFGTSRFVAQYDSTRNNRLEEGLAGSVEGQIGADRSFSASKLENYRLSGELNLPLHALFEQVLTVGAEWNKETLNDPSSLKQGFVGSDSLPGTPAAGSRSPKSKAEIRALYVEDNIELRPGTMLTPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAPNLYQSNPNYLLYTRGNGCPIQTSSGGCYLVGNENLDAETSVNKELGIEFRRDGWVAGLTYFRNDYKNKIVAPLDVMGQTGTGNNILQWSNAKKAVVEGLEGNLLVPLHEDLSWSTNLTYMLQSKDKDTGNPLSVIPEYTLNSTLDWQASERLSTQLTSTIYGRQEPPKHGTSRNTPVVSRKEVGTYGIWGVSAGYTFSENLSVRGGVSNLFDKRLYRQGNSFDAGAATYNEPGRAYYVSMTTSF