wanglab/gogpt-training-data huggingface dataset:
Protein: Inner kinetochore subunit NKP2 (Constitutive centromere-associated network protein NKP2) (Non-essential kinetochore protein 2) (Q06162)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:12408861, ECO:0000269|PubMed:29046335}. Note=Associated with kinetochores (PubMed:12408861).
Interaction partners:
- Inner kinetochore subunit OKP1
- Inner kinetochore subunit NKP1
- Inner kinetochore subunit CHL4
- Inner kinetochore subunit CTF19
- Inner kinetochore subunit AME1
- Inner kinetochore subunit IML3
- Inner kinetochore subunit MCM21
- Inner kinetochore subunit MCM16
- Inner kinetochore subunit CTF3
- Inosine-5'-monophosphate dehydrogenase 4
Sequence:
MNSEQLLHNYVSDSLLTTLISFQEFKQQLQSYTSDEQQLQHWYELLQARDARVTSELEARIKQFFITLRSRLLRFLESEQLSHSLSLETLIDALYKINDLLQQRLQILDDAIQEKTSELAEFENMVRSPSAGDNAIPGLLQIIQSYINLLEEN
Protein: Microspherule protein 1 (Q5BJR5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MDKDSQGLLDSSLMASGTASRSEDEESLAGQKRASSQALGTIPKRRSSSRFIKRKKFDDELVESSLAKSSTRVKGAGSVESGRCSGSEPSSSEKKKVSKAPSTPVPPSPAPTPGLTKRVKKSKQPLQVTKDLGRWKPADDLLLINAVLQTNDLTSVHLGVKFSCRFTLREVQERWYALLYDPVISKLACQAMRQLHPEAIAAIQSKALFSKAEEQLLSKVGSTSQPTLETFQDLLHRHPDAFYLARTAKALQAHWQLMKQYYLLEDQTVQPLPKGDQVLNFSDAEDLIDDSELKDMRDEVLEHELTVADRRQKREIRQLEQELHKWQVLVDSITGMSSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNGDFFIANEGRRPIYIDGRPVLCGSKWRLSNNSVVEIASLRFVFLINQDLIALIRAEAAKITPQ
Protein: Uncharacterized protein (Q57Z37)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Rhodanese domain-containing protein
- Large ribosomal subunit protein uL3m
- Uncharacterized protein
- 50S ribosomal protein L16, putative
- Mitochondrial RNA binding complex 1 subunit
- 50S ribosomal protein L17, putative
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MRRCIPARGGFTMKYKKGTGLWDEDHVNDYKTNRYLSARATMRWYQEMERHQTRNSLNARRATQSHNNNRGLHHTGRGAFERELERRGVQVEKYPLTTTTGAMRVAELVILRRMELEKRAEEALAEQRAELQKKNPTPSEWYDESKGPLNPNFLRSMRSHYEVDIANLPDTPLIRGQREFFIGEERGNGAA
Protein: Uncharacterized protein (Q385M7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MIENVTAVCCEQTVSASDKVEDMIPSSGAAADTDTCSVSNSALGGDNENRAKETVHFPRTPVRVVTPLQRRSPLGHLTPPATPLCRTPPLAVPCTPDGERLPPNHSKSLCPNDQDERFQTPTVKTPMLAADQESPVKHRHQRRKFLDNYFFLKNLNALPLTPERKKERDAGPFCRRALQFPSPNTSMHSVGMDAISSPLPPLSPSTPVTRPPQPSAEGSDVTEVQTAGRRFVRSFTTQSAEQSYTKSGDILSVPEGERCESVQASVKEICPAADASSRASSSLGEQNDRGRSPSPIAVDEEGEVTRPPHEVARTVTPCPLRSSEVGGKAEDFPPDAPIDAQEQGVQPLDNSGFAPIGVNDVSLHITSTASCQSGEQSTLCEGHDCPELGVLNTKCVTVGARTSLRTDGSKSGGRVEELSLDQRKLLTEQPTRSRGGAVFPTEESLRGFSDKLFDQYQNKLAHLAFDVLYTRMVASPNTQMLESHGRRLICMRRDAWIRELIELERLLLPLVRGRSRSRGGNKNSARSKSSKRAESPRSDGSSKRSRSARCYILPTVHDDKGYTRDYLGDGPSCKGFNKNVTQSVVIMDATDVVEEEEKPKAHTTAPDPILSSHHKVVSSGGCFPFVHRLSSRGGRRKERQSRGATTIPAE
Protein: Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4) (Q9QUJ7)
Organism: Mus musculus (Mouse)
Function: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (By similarity).
Subcellular location: Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O60488}; Single-pass type III membrane protein {ECO:0000250}. Cell membrane {ECO:0000250|UniProtKB:O60488}.
Interaction partners:
- Fatty acid synthase
- Carnitine O-palmitoyltransferase 1, liver isoform
- Monoglyceride lipase
- Lipoprotein lipase
- Beta-alanine-activating enzyme
- Lysophospholipid acyltransferase 5
- Phospholipid hydroperoxide glutathione peroxidase GPX4
- Lysosomal thioesterase PPT2
- Palmitoyl-protein thioesterase 1
- Palmitoyl thioesterase CPT1C
Sequence:
MNLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKTINRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEGSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK
Protein: Apoptosis inhibitor 5 homolog (API-5) (Antiapoptosis clone 11 protein homolog) (AAC-11) (Protein cassowary) (Q9V431)
Organism: Drosophila melanogaster (Fruit fly)
Function: Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB2
Sequence:
MDNIERLYKCYEILSEAGDKISEHVDEYKEILKAVKGTSKEKRLASQFIGNFFKHFPDLADTAIDAQFDLCEDDDTQIRRQAIKDLPKLCQGNADATIRVGDTLAQLLILDDPTELQQVNNSLLAIIKLDTKSSIAGLFQQISTGDETTRERCLKFIATKLLTMGPTVITKEIEDYIVEEIKKALQDVTADEFHLCMTILGATKLGSTITGHAELVKLATEQAELNNTDADIIAVDDEVVERFIQCASAAAPYFSKTIKSTAFVAHVCDKLLPIKTWNMIATAVSQDQIQLRLLKVFAEMITNTDKLDNASERINAVYNVLLEYMPLPKLSDEDLGDTPPSFQFSHAECLLYALHTLGKNHPNSLSFVEDAEKLKDFRARLQYLARGTQGYIKKLEESLKGKTGEELKTEENQLKQTALKTTSNINILIRDLFHSPPIFKHDIVLSWIVPKNNKLGKRHAPITFGEKAAANGKDKDQEPEKKSRPSNDQKFYSPPSGKYSNKVNQSYGNNNRTRQRGGGGGGGSGGGYRNRRFNKY
Protein: Ceramide kinase-like isoform 8 (G0XYG0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDCIPTLVGAELPLGFIPAGSTNALAHSLFGTPHVVTATMHIILGHIRSVDVCTFSSAGKLLCFGFSAMFGFGGRTLALAEKYRWMSPSQRRDFAIIKALAKLKPEDCKISFLLAGCSQNKQERKSQRSAESDCGGHWQTIQGQFLNISIMAMPCPCSMAPRGFTPDTRLHNGSMALRVVRNTTRSEFVKHLKRHSSVKNQFNFPFVETYIIEEVKIHPKSNSNGYSPQEEGGNHTTASEHGFPWNVDGDLMEAASEVHIRLHPRLIRLYGGSLEEMNDCKVACDCI
Protein: Putative GIPL galf transferase (EC 2.4.1.-) (Q4QD44)
Organism: Leishmania major
Interaction partners:
Sequence:
MRKSTSVYTLRSHRCFITLRAVIPILIFICLCGAVGTIFLTSSHQSALGWTREPTTSAPSGELTTTEPGEPRRSMTPTSAITTSAPATATTAEQTPLPPEQTSMFDAPGTPTPAVSAASARATGAQDSSTLMEGAKTETTKQNLAMKGLDRWMKMQLPADWMECIRQNLQLDKHGQPMHAVTEMKDAIPLLITPLTGDVKFFPYFVCSMDVAVRYHYVIQNERDPDTTAVIDDLQRRFGNSGRLLVVRNRYNRGYSGSMNQAFEWALKERTAEEVPWVFACGVDAIFEPGLLAKMIEVVQQNTRGDAAMLAALRAEVELEERLVREGNYSYYERWAPRGRPLKVLRSGYPGVPLNVRTAPLLPDRIRYTVADENRESGIVRPAELRTRFFGNYVATVTPVPDALGTIAVTRLALSAVGYFDENYFPAYMDDIDLRWRHFAYGFGALHGERNGPVTRWHHYNAANLRGSPFVDPDLEKYGTEDNYSRRAFLSYIRRSKGIYDKLKYGPRDMDGVWRQAAQKAEFKYSSFNVSHYPADTWVLDEDARGCMFHHTYNYKTQNWSRPSDCSYNPRTLEESGILGVDQLASYRSMLAEKAFAYQ
Protein: StAR-related lipid transfer protein (Q8I298)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MSLKRRKFILLSFVFSVVELIFGYDNIINNYGGLSSVVVYNKNVGINKIGDNVYKNKIKSRILKENKEESLETAAVNENTKDVKDSCNYSTPSSVFNNDKENTASFIKTGESYDGNNVQAQAQAQAQAEAEGSLENAAVNLRTKSATLINDGMLDYYLNFCDQVNNKTFPFNECTNLHTSDMVTLCKNNNDEKSKITYDLLGYGEMDDVSAYSLSYALNDVETIKDWNKNIYKLNYLNLKKSDIQEKIDKNEKINVNNFILQSEKDVPEDERKYLYLINGLPWPFKSQDTIYEVYQKYYNNKNMLLIINKSLNDVFDNNSSYARINNYENFFCIYPKSKNSYDKGVKYVMSIIYDVNIPKFIQNNILNQIFPDLIFNLHNTSIAITNKTVGTVVDLSKNEQNAWHAHSLKNVKPEDTPNTEHVQTDPENSYGLGFIKMIFVDGPYNLWIINVNFFKKIFGIFFNKD
Protein: Protein TOPLESS (WUS-interacting protein 1) (Q94AI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional corepressor. May repress the expression of root-promoting genes in the top half of the embryo to allow proper differentiation of the shoot pole during the transition stage of embryogenesis. Regulates the expression of PLT1 and PLT2. Negative regulator of jasmonate responses. Negative regulator of auxin responses. Negative regulator of multiple floral organ identity genes. Required for ovule development.
Subcellular location: Nucleus {ECO:0000269|PubMed:16763149, ECO:0000269|PubMed:18258861, ECO:0000269|PubMed:27015278, ECO:0000269|PubMed:28526412}.
Interaction partners:
- AFP homolog 2
- Histone deacetylase 19
- Auxin transporter protein 1
- Protein BRASSINAZOLE-RESISTANT 2
- Corepressor
- Auxin-responsive protein IAA12
- Histone deacetylase 6
- Protein TIFY 5A
- Two-component response regulator-like APRR5
- Protein TIFY 11A
Sequence:
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEDEVHNGNWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDKHDRPKAVDILVKDLKVFSTFNEELFKEITQLLTLENFRENEQLSKYGDTKSARAIMLVELKKLIEANPLFRDKLQFPTLRNSRLRTLINQSLNWQHQLCKNPRPNPDIKTLFVDHSCGPPNGARAPSPVNNPLLGGIPKAGGFPPLGAHGPFQPTASPVPTPLAGWMSSPSSVPHPAVSAGAIALGGPSIPAALKHPRTPPTNASLDYPSADSEHVSKRTRPMGISDEVNLGVNMLPMSFSGQAHGHSPAFKAPDDLPKTVARTLSQGSSPMSMDFHPIKQTLLLVGTNVGDIGLWEVGSRERLVQKTFKVWDLSKCSMPLQAALVKEPVVSVNRVIWSPDGSLFGVAYSRHIVQLYSYHGGEDMRQHLEIDAHVGGVNDISFSTPNKQLCVITCGDDKTIKVWDAATGVKRHTFEGHEAPVYSVCPHYKENIQFIFSTALDGKIKAWLYDNMGSRVDYDAPGRWCTTMAYSADGTRLFSCGTSKDGESFIVEWNESEGAVKRTYQGFHKRSLGVVQFDTTKNRYLAAGDDFSIKFWDMDAVQLLTAIDGDGGLQASPRIRFNKEGSLLAVSGNENVIKIMANSDGLRLLHTFENISSESSKPAINSIAAAAAAAATSAGHADRSANVVSIQGMNGDSRNMVDVKPVITEESNDKSKIWKLTEVSEPSQCRSLRLPENLRVAKISRLIFTNSGNAILALASNAIHLLWKWQRNERNATGKATASLPPQQWQPASGILMTNDVAETNPEEAVPCFALSKNDSYVMSASGGKISLFNMMTFKTMATFMPPPPAATFLAFHPQDNNIIAIGMDDSTIQIYNVRVDEVKSKLKGHSKRITGLAFSNVLNVLVSSGADAQLCVWNTDGWEKQRSKVLPLPQGRPNSAPSDTRVQFHQDQAHFLVVHETQLAIYETTKLECMKQWAVRESLAPITHATFSCDSQLVYASFMDATVCVFSSANLRLRCRVNPSAYLPASLSNSNVHPLVIAAHPQEPNMFAVGLSDGGVHIFEPLESEGKWGVAPPAENGSASGAPTAPSVGASASDQPQR
Protein: Nucleoside diphosphate kinase (EC 2.7.4.6) (D3ZMT9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MGCLFDRAALRALLCGPRFQCLLVRPSSGGPPWPQERTLVAVKPDGVQRRLVGTVIHRFERRGFKLVGMKMLQAPESILAEHYRDLQRKPFYPALISYMSSGPVVAMVWEGHNVVHISRAMIGHTDSTEAAPGTIRGDFSVHISRNVIHASDSVDGAQREIELWFQSSELLNWADGGHHSSCYPA
Protein: Sugar phosphatase YbiV (EC 3.1.3.23) (P75792)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of ribose-5-phosphate, glucose-6-phosphate, fructose-1-phosphate, acetyl-phosphate, glycerol-1-phosphate, glycerol-2-phosphate, 2-deoxy-glucose-6-phosphate, mannose-6-phosphate and fructose-6-phosphate. Appears to have a low level of phosphotransferase activity using monophosphates as the phosphate donor.
Interaction partners:
- Hexitol phosphatase B
- Uncharacterized protein YbiU
- HMP-PP phosphatase
Sequence:
MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIKFVVASGNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQLNFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPLVIDKLHVALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGNDAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNTSPFNS
Protein: Lamina-associated polypeptide 2, isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)] (P42166)
Organism: Homo sapiens (Human)
Function: May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.
Subcellular location: Nucleus. Chromosome. Note=Expressed diffusely throughout the nucleus.
Interaction partners:
- Prelamin-A/C
- Lamin-B1
- Barrier-to-autointegration factor
- Emerin
- Inner nuclear membrane protein Man1
- Erbin
- Barrier-to-autointegration factor-like protein
- Lamin-B2
- Desmoglein-2
- RNA-binding protein 20
Sequence:
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSKGPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDSDRYSDNEEGKKKEHKKVKSTRDIVPFSELGTTPSGGGFFQGISFPEISTRPPLGSTELQAAKKVHTSKGDLPREPLVATNLPGRGQLQKLASERNLFISCKSSHDRCLEKSSSSSSQPEHSAMLVSTAASPSLIKETTTGYYKDIVENICGREKSGIQPLCPERSHISDQSPLSSKRKALEESESSQLISPPLAQAIRDYVNSLLVQGGVGSLPGTSNSMPPLDVENIQKRIDQSKFQETEFLSPPRKVPRLSEKSVEERDSGSFVAFQNIPGSELMSSFAKTVVSHSLTTLGLEVAKQSQHDKIDASELSFPFHESILKVIEEEWQQVDRQLPSLACKYPVSSREATQILSVPKVDDEILGFISEATPLGGIQAASTESCNQQLDLALCRAYEAAASALQIATHTAFVAKAMQADISQAAQILSSDPSRTHQALGILSKTYDAASYICEAAFDEVKMAAHTMGNATVGRRYLWLKDCKINLASKNKLASTPFKGGTLFGGEVCKVIKKRGNKH
Protein: Myosin-2 (Cell division control protein 66) (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2) (P19524)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Essential for the delivery of secretory vesicles to sites of active growth during bud emergence and cytokinesis. Required for segregation and inheritance of peroxisomes, late Golgi compartments, mitochondria and the vacuole to the daughter cell during cell division. Also required for correct alignment of the spindle during mitosis.
Subcellular location: Bud neck {ECO:0000269|PubMed:8188749}. Bud tip {ECO:0000269|PubMed:8188749}. Note=Concentrates to sites of polarized growth, namely to the bud tip during S and G2 phases of the cell cycle and to the bud neck during cytokinesis.
Interaction partners:
- vacuole-related protein 17
- Myosin light chain 1
- Kinesin-related protein SMY1
- Mitochondrial MYO2 receptor-related protein 1
- Ras-related protein SEC4
- Inheritance of peroxisomes protein 2
- Actin
- Karyogamy protein KAR9
- GTP-binding protein YPT31/YPT8
- GTP-binding protein YPT11
Sequence:
MSFEVGTRCWYPHKELGWIGAEVIKNEFNDGKYHLELQLEDDEIVSVDTKDLNNDKDQSLPLLRNPPILEATEDLTSLSYLNEPAVLHAIKQRYSQLNIYTYSGIVLIATNPFDRVDQLYTQDMIQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASVEEENSATVQHQVEMSETEQKILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKDTSIIGARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLTDASDYFYMNQGGDTKINGIDDAKEYKITVDALTLVGITKETQHQIFKILAALLHIGNIEIKKTRNDASLSADEPNLKLACELLGIDAYNFAKWVTKKQIITRSEKIVSNLNYSQALVAKDSVAKFIYSALFDWLVENINTVLCNPAVNDQISSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFNDNQPCIDLIENKLGILSLLDEESRLPAGSDESWTQKLYQTLDKSPTNKVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNETLINILEGLEKAAKKLEEAKKLELEQAGSKKPGPIRTVNRKPTLGSMFKQSLIELMNTINSTNVHYIRCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLRYYILIPHEQWDLIFKKKETTEEDIISVVKMILDATVKDKSKYQIGNTKIFFKAGMLAYLEKLRSNKMHNSIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIRQRVNDEMKVNCATLLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEYNAAVTIQSKVRTFEPRSRFLRTKKDTVVVQSLIRRRAAQRKLKQLKADAKSVNHLKEVSYKLENKVIELTQNLASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHLIDIDNQKSKDMELQKTIENNLQSTEQTLKDAQLELEDMVKQHDELKEESKKQLEELEQTKKTLVEYQTLNGDLQNEVKSLKEEIARLQTAMSLGTVTTSVLPQTPLKDVMGGGASNFNNMMLENSDLSPNDLNLKSRSTPSSGNNHIDSLSVDRENGVNATQINEELYRLLEDTEILNQEITEGLLKGFEVPDAGVAIQLSKRDVVYPARILIIVLSEMWRFGLTKQSESFLAQVLTTIQKVVTQLKGNDLIPSGVFWLANVRELYSFVVFALNSILTEETFKNGMTDEEYKEYVSLVTELKDDFEALSYNIYNIWLKKLQKQLQKKAINAVVISESLPGFSAGETSGFLNKIFANTEEYTMDDILTFFNSIYWCMKSFHIENEVFHAVVTTLLNYVDAICFNELIMKRNFLSWKRGLQLNYNVTRLEEWCKTHGLTDGTECLQHLIQTAKLLQVRKYTIEDIDILRGICYSLTPAQLQKLISQYQVADYESPIPQEILRYVADIVKKEAALSSSGNDSKGHEHSSSIFITPETGPFTDPFSLIKTRKFDQVEAYIPAWLSLPSTKRIVDLVAQQVVQDGH
Protein: Leucine-rich repeat (LRR) family protein (Q9FW48)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable methyltransferase PMT15
- Similar to part of disease resistance protein domain-containing protein)
- Similar to part of disease resistance protein domain-containing protein)
- Probable pectin methyltransferase QUA3
- DNA ligase-like protein
- Eukaryotic aspartyl protease family protein
- Berberine bridge enzyme-like 26
Sequence:
MNSCCFPLFIFAFVIFLRCLSPIEAATCHPDDEAGLLAFKSGITQDPTGILSSWKKGTDCCSWKGVGCLTNRVTGLTINGQSDVTGSFLSGTISPSLAKLQHLVGIYFTNLRNITGSFPQFLFQLPNVKQVYFTNSRLSGPLPANIGALSELGELSLDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLKPILNYLDLSQNNLSGTIPTFLSNFKVLDSLDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPAMKNVDGLATLDLSYNQFHLKTIPKWVTSSPSMYSLKLVKCGINMSLDNWKPVRPNIYFYIDLSENEISGSLTWFFNLAHNLYEFQASGNKLRFDMGKLNLSERLESLDLSRNLIFGKVPMTVAKLQKLNLSHNHLCGKLPVTKFPASAFVGNDCLCGSPLSPCKI
Protein: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (Q4KLI0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR038126}.
Interaction partners:
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- AT-rich interaction domain 1A
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
- AT-rich interactive domain-containing protein 2
- AT-rich interaction domain 1B
- Protein polybromo-1
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
- Actin-like protein 6A
Sequence:
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW
Protein: RNA-binding protein 208 (Q6YZW2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: RNA-binding protein.
Interaction partners:
- Nuclear cap-binding protein subunit 1
- Nuclear cap-binding protein subunit 2
- Eukaryotic translation initiation factor 4E-1
- U1 small nuclear ribonucleoprotein C
- Arginine/serine-rich splicing factor, putative, expressed
Sequence:
MNGAGGNHQQQQQQQQRLRQQQQQQALLMQQALQQQQQYQSGVLAAAAAAAMTQMEPISNGNLPPGFDPSTCRSVYVGNVHPNVTESLLIEVFQSSGLVERCKLIRKEKSSFGFVDYYDRRSAALAIMTLHGRHICGQAIKVNWAYASTQREDTSGHFHIFVGDLSSEVNDATLYACFSAYPSCSDARVMWDNKTGRSRGYGFVSFRNQQEAETAITEMTGKWLGSRQIRCNWATKNNAEEKQETDNHNAVVLTNGSSSNPGMEASQDTGSKENPENNPDCTTVYVGNLGHEVNRDELHRHFYNLGVGAIEEVRVQQDKGFGFVRYSNHGEAALAIQMANGLVVRGKPIKCSWGNKPTPPGTSSKPLPPPLPSYQPVPMAGVPQGFSAADIVAYQRQLTLSQVAAGQIAGQHGLAGQVSAGLLAAGSQALYDGYPNQSSAQQLMYYN
Protein: At5g27290 (Stress regulated protein) (Q08AA8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Pentatricopeptide repeat-containing protein At1g31920
- Tropinone reductase homolog At2g29290
- Paraxanthine methyltransferase 2
- Nudix hydrolase 2
- Calvin cycle protein CP12-2, chloroplastic
- Marker for oxidative stress response protein
- Photosystem I chlorophyll a/b-binding protein 6, chloroplastic
- Lon protease
Sequence:
MVMLLHSVGLIPCSNQQKSFLFHSYYRYRCIVCSSETGLSIRRQALEQVDSKLSSGDERAALSLVKDLQGKPDGLRCFGAARQVPQRLYTLEELKLNGINAASLLSPTDTTLGSIERNLQIAAVSGGIVAWKAFDLSSQQLFFLTLGFMFLWTLDLVSFNGGIGSLVLDTTGHTFSQRYHNRVVQHEAGHFLVAYLVGILPRGYTLSSLEALQKEGSLNIQAGSAFVDYEFLEEVNSGKVSATMLNRFSCIALAGVATEYLLYGYAEGGLDDISKLDGLVKSLGFTQKKADSQVRWSVLNTILLLRRHEIARSKLAQAMSKGESVGSCIQIIEDSIDPSDI
Protein: Very long chain fatty acid elongase 6 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl6) (ELOVL fatty acid elongase 6) (ELOVL FA elongase 6) (Elongation of very long chain fatty acids protein 6) (Fatty acyl-CoA elongase) (Long chain fatty acid elongase) (Myelin-associated SUR4 protein) (Very long chain 3-ketoacyl-CoA synthase 6) (Very long chain 3-oxoacyl-CoA synthase 6) (Q920L5)
Organism: Mus musculus (Mouse)
Function: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03206, ECO:0000269|PubMed:11567032, ECO:0000269|PubMed:12084938}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03206}.
Interaction partners:
- Very long chain fatty acid elongase 5
- Fatty acid synthase
- Very-long-chain 3-oxoacyl-CoA reductase
- 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
- Acetyl-CoA carboxylase 1
- Acyl-CoA desaturase 1
- ATP-citrate synthase
- Thyroid hormone-inducible hepatic protein
- Peroxisome proliferator-activated receptor alpha
- Sterol regulatory element-binding protein 1
Sequence:
MNMSVLTLQEYEFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKRAKFELRKPLVLWSLTLAVFSIFGALRTGAYMLYILMTKGLKQSVCDQSFYNGPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMGCVINYLVFNWMQHDNDQCYSHFQNIFWSSLMYLSYLVLFCHFFFEAYIGKVKKATKAE
Protein: Allatostatin C receptor 1 (Orphan G-protein coupled receptor) (Q9VVQ1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MFTWLMMDVLQFVKGEMTADSEANATNWYNTNESLYTTELNHRWISGSSTIQPEESLYGTDLPTYQHCIATRNSFADLFTVVLYGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLAVADECFLIGIPFLLYTMRICSWRFGEFMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVILYASTVEQEDGINYSCNIMWPDAYKKHSGTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPKPGTKSKEKRRAHRKVTRLVLTVISVYILCWLPHWISQVALIHSNPAQRDLSRLEILIFLLLGALVYSNSAVNPILYAFLSENFRKSFFKAFTCMNKQDINAQLQLEPSVFTKQGSKKRGGSKRLLTSNPQIPPLLPLNAGNNNSSTTTSSTTTAEKTGTTGTQKSCNSNGKVTAPPENLIICLSEQQEAFCTTARRGSGAVQQTDL
Protein: Glycosyl hydrolase, family 1 (D1YLM1)
Organism: Lactobacillus gasseri 224-1
Interaction partners:
Sequence:
MSFPKNFLWGGATAANQIEGAYDEDGKGLSVTDITTAGSLDAPRMLTYKLNGKLEKTPAIPGAGLPEGAVGAIDPNEYYPNHVAIDFYHHYKEDIKMFAEMGFKTFRLSIAWTRIFPKGDEEKPNQAGLDFYRHVFEECKKYGIEPLVTISHYEDPLYLSEKYHDWGDRKMIDMYVKYATTLFEEYRGLVKYWLTFNEINSTLLMLSSFGNNVTDDKVYQHAYQKLHYQFVASARAVKIAHALDPNYVVGNMICGIVDYPLTPDPKDILANRHMWEQNIFYCGDVQAKGKYPTYAKRLWNEHNVHLDITEQDRKDLLEGKVDIYTFSYYMSNIITTHEVKDKVGGNFAAGVKNPYLKYSEWGWATDPDGLQYYLEVMYDRYDIPMMVVENGLGAVDKISDDGKIHDDYRIDYLRMHIKAMERAIDDGVDLIGYTTWGCIDLVSAGTGQMSKRYGFIYVDRDDEGKGTLKRMPKDSFYWYKKVIESDGKDLD