wanglab/gogpt-training-data huggingface dataset:
Protein: 5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor) (O70212)
Organism: Cavia porcellus (Guinea pig)
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:P46098}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P23979}. Cell membrane {ECO:0000250|UniProtKB:P46098}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P23979}.
Interaction partners:
- 5-hydroxytryptamine receptor 3B
- RIC3 acetylcholine receptor chaperone
Sequence:
MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA
Protein: MHC class I antigen (Q95HD8)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
SHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITRRKWEAAHAAEQQRAYLEGRCVEWLRRYLENGKETLQRT
Protein: Enoyl-[acyl-carrier-protein] reductase [NADH] (ENR) (EC 1.3.1.9) (NADH-dependent enoyl-ACP reductase) (Trans-2-enoyl-CoA reductase [NADH]) (TER) (EC 1.3.1.44) (Q62L02)
Organism: Burkholderia mallei (strain ATCC 23344)
Function: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the NADH-dependent reduction of the carbon-carbon double bond in the enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It is also able to reduce trans-2-dodecenoyl-CoA (DD-CoA).
Interaction partners:
Sequence:
MIIKPRVRGFICVTTHPAGCAASVREQIAYVARRGPIERGPKKVLVIGASTGYGLAARIAAAFGVGAATLGVFFERAPADAKPGTAGWYNSAAFHDEAAARGLQATSVNGDAFSDEIKHKTIDAIRRDLGQVDLVVYSVAAPRRTHPKTGVTHQSTLKPIGHAVRLRGIDTDNEAIKETLLQPATPDEIADTVAVMGGEDWRMWIDALDAAGVLADGAKTTAFTYLGEQVTHDIYWNGSIGEAKKDLDRTVLALRGKLAARGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKARGTHEGCIEQVDGLLRDSLYSAQPHVDAEGRLRADRLELDPAVQARVLELWDQVTDDNLYTLTDFAGYKAEFLRLFGFGIDGVDYDAPVEPNVRIPNLIE
Protein: Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium-dependent glucose cotransporter) (Sodium/glucose cotransporter KST1) (rkST1) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11) (Q9Z1F2)
Organism: Rattus norvegicus (Rat)
Function: Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Can also transport D-chiro-inositol (DCI) but not L-fucose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney (By similarity).
Subcellular location: Membrane {ECO:0000269|PubMed:17932225}; Multi-pass membrane protein {ECO:0000269|PubMed:17932225}. Apical cell membrane {ECO:0000269|PubMed:17932225}; Multi-pass membrane protein {ECO:0000269|PubMed:17932225}. Note=Located on apical membrane of enterocytes. Located on membrane of kidney brush border membrane vesicles (BBMVs) and apical membrane of proximal convoluted tubules (By similarity). {ECO:0000250|UniProtKB:Q28728, ECO:0000269|PubMed:17932225}.
Interaction partners:
- Solute carrier family 2, facilitated glucose transporter member 5
Sequence:
MESTTSSPQPPPSDALEAFPQKSMEPADIVVLVLYFLFVLAVGLWSTVRTKRDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAAVGISVAAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLKRRFGGSRIPITLASIYPSTHSLTILQVDMYAGAIFIQQSLHLDLYLAIVGLLAVTALYTVAGGLAAVIYTDALQTVIMLIGAFILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGILFGMSIPSLWYWCTDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPLFLMVFPGMVSRILFPDQVACAHPDICQRVCSNPSGCSDIAYPKLVLELLPTGLRGLMMAVMVAALMSSLTSIFNSASTIFTMDLWHHIRPRASERELMIVGRVFVLALVLVSILWIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFSGLILGLLLGLVRLILDFVYVQPRCDQPDDRPAVVKDVHYLYFSMILSSTTLITVFTVSWFTETPSKEMVSRLTWFTRHEPVAQKDSVPPENPLSLTISQNGTTEATGISIQLESVQEATTKAHSDGVSPKQSKVLKAILWLCGMEKDKEEPPSKVEPVIVSLEENPLVKTLLDVNCIVCISCAIFLWGYFA
Protein: GH09028p (Q8I0D5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSEAGRFSYVTFVDSAPMVLKETNINKMHTPSEGMLHINPKDFVNFNSKNAEATMTIKSIATSAVTYKIQTTSPEKFRVRPRCGIIQPNQEATINIWLKSEHKLSDDSKDKFLVMAMVAPGGECGGADVTELWRSKSPTSADVEQHRLVCRFDENKSKAQLDCASKSSKASVDCSKKSGAGVDPATAMERQLAFTQNLQYVTLALLFLLFAGFGFLMYQQLGQHAATCPKATAYSCAKRK
Protein: RNA-binding protein EWS (Q61545)
Organism: Mus musculus (Mouse)
Function: Might function as a transcriptional repressor.
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation. {ECO:0000250}.
Interaction partners:
- ATP-dependent RNA helicase A
- Y-box-binding protein 1
- Heterogeneous nuclear ribonucleoprotein M
- TAR DNA-binding protein 43
- U1 small nuclear ribonucleoprotein C
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Heterogeneous nuclear ribonucleoprotein A1
- Probable ATP-dependent RNA helicase DDX5
- Non-POU domain-containing octamer-binding protein
- Ribonuclease 3
Sequence:
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYATSYGQPPTGYSTPTAPQAYSQPVQGYGTGTYDSTTATVTTTQASYAAQTAYGTQPAYPTYGQQPTATAPTRPQDGNKPAETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSSQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSLSGPDNRGRGRGGFDRGGMSRGGRGGGRGGLGAGERGGFNKPGGPMDEGPDLDLGLPIDPDEDSDNSAIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGMPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Protein: Col2a1a protein (Collagen, type II, alpha 1a) (B3DLK0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Transcription factor sox9a
- Sp7 transcription factor.
- Collagen alpha-2
- SRY-box transcription factor 5.
- Indian hedgehog B protein
- RUNX family transcription factor 2b.
- SRY-box transcription factor 6.
- Integrin, alpha 10
- Runt-related transcription factor.
- Collagen, type XI, alpha 2.
Sequence:
MFRLLDSRTLLLLVATHSVLLSLVRCQQEDDRSLGAKGQKGEPGDITDVVGPRGPAGPMGPPGEQGTRGERGAKGEKGSPGPRGRDGEPGTPGNPGPPGPPGPNGPPGLGGNFAAQMAGGFDEKAGGAQMGVMQGPMGPMGPRGPPGPSGAPGPQGFQGNPGETGEPGPAGALGPRGPPGPPGKPGSDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGIKGHRGHPGLDGAKGEAGAAGAKGEAGSNGESGAPGPMGPRGLPGERGRPGATGAAGARGNDGLPGPAGPPGPVGPAGAPGFPGSPGSKGEAGPTGARGPEGAQGPRGEAGTPGSPGPAGASGNPGTDGIPGAKGSAGASGIAGAPGFPGPRGPPGPQGATGPLGPKGQSGDPGIPGFKGEAGPKGERGVLGPQGPPGPSGEEGKRGPRGEPGSAGPLGPPGERGAPGNRGFPGQDGLAGAKGAPGDRGVPGLSGPKGGTGDPGRPGEPGLPGARGLTGRPGDAGAQGKVGATGAPGEDGRPGPPGPLGARGQPGVMGFPGPKGANGEPGKPGEKGLVGRTGLRGLPGKDGETGPSGPPGPVGAVGERGEQGQPGPSGFQGLPGPTGAPGEPGKPGDQGVPGEGGAAGPTGPRGERGFPGERGGAGPQGLQGPRGLPGTPGTDGPKGAIGPAGAAGAQGPPGLQGMPGERGAVGISGAKGDRGDSGEKGPEGAPGKDGSRGLTGPIGPPGPSGPNGAKGETGPIGSIGAPGARGAPGDRGEIGAPGPAGFAGPPGADGQPGNKGEQGESGQKGDSGAPGPQGPSGAPGPVGPTGVTGPKGARGAQGAPGATGFPGAAGRVGPPGPNGNPGAAGPAGPSGKDGPKGVRGDAGPPGRAGDAGLRGPPGAPGEKGEAGEDGPPGPDGPSGPAGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGGSGDRGPPGPVGPPGLTGPAGETGREGNPGSDGPPGRDGAAGVKGERGNTGPIGAPGAPGAPGAPGSVGPIGKQGDRGENGPQGPAGPPGPAGARGMVGPQGPRGDKGEAGEAGERGQKGHRGFTGLQGLPGPPGSPGDQGAAGPAGPSGAKGPSGPVGPAGKDGSNGQPGPIGPPGPRGRSGESGPVGPPGNPGPPGPPGPPGPGIDMSAFAGLSQPEKGPDPLRYMRADEASSSLRQHDVEVDATLKSINGQIEDIRSPDGSRKNPARSCRDLKLCHPEWKSGDYWVDPNLGSAADAIKVFCNMETGETCVKPSTPKIPRKNWWTSKSKAQKHVWFGESMNGGFHFSYADGSQTPSTTTIQLNFLRLLSTEATQTITYHCKNSVAYMDQATGNLKKAILLQGSNDVEIRAEGNSRFTYGVLEDGCKKHTGQWAKTVIEYKTQKTSRLPIMDIAPMDIGGADQEFGVDIGAVCFL
Protein: U4/U6 small nuclear ribonucleoprotein PRP4-like protein (Protein EMBRYO DEFECTIVE 2776) (Protein LACHESIS) (O22212)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (By similarity). Essential for reproduction. In female gametophyte, is necessary for the egg cell and central cell fate determination and hence reproductive success. Involved in a mechanism that prevents accessory cells from adopting gametic cell fate. Modulates egg cell signaling center that regulates the development of all female gametophytic cells.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:18702672}. Note=Colocalizes with CLO. {ECO:0000269|PubMed:18702672}.
Interaction partners:
- Protein STABILIZED1
- 110 kDa U5 small nuclear ribonucleoprotein component CLO
- Small nuclear ribonucleoprotein Sm D2
- Sm-like protein LSM8
- Sm-like protein LSM5
- Sm-like protein LSM2
- Sm-like protein LSM4
- Protein RDM16
- 109 kDa U5 small nuclear ribonucleoprotein component GFL
- Splicing factor 3B subunit 4
Sequence:
MEPNKDDNVSLAATAQISAPPVLQDASSLPGFSAIPPVVPPSFPPPMAPIPMMPHPPVARPPTFRPPVSQNGGVKTSDSDSESDDEHIEISEESKQVRERQEKALQDLLVKRRAAAMAVPTNDKAVRDRLRRLGEPITLFGEQEMERRARLTQLLTRYDINGQLDKLVKDHEEDVTPKEEVDDEVLEYPFFTEGPKELREARIEIAKFSVKRAAVRIQRAKRRRDDPDEDMDAETKWALKHAKHMALDCSNFGDDRPLTGCSFSRDGKILATCSLSGVTKLWEMPQVTNTIAVLKDHKERATDVVFSPVDDCLATASADRTAKLWKTDGTLLQTFEGHLDRLARVAFHPSGKYLGTTSYDKTWRLWDINTGAELLLQEGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMRKSLYIIPAHANLVSQVKYEPQEGYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVASLDITADSSCIATVSHDRTIKLWTSSGNDDEDEEKETMDIDL
Protein: Enoyl-[acyl-carrier-protein] reductase [NADPH] (ENR) (EC 1.3.1.39) (A0A0H3JLH9)
Organism: Staphylococcus aureus (strain N315)
Interaction partners:
Sequence:
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
Protein: Kank, isoform C (A1Z9W5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLWIVFWLAVLWLWHEAKIPQETRPIASSANPAPAGITRSVRSCNCCPYGYHIDLDFVRYCEALALEKPSEEEQRRRDRRRSRKSMEFMLGFESLFGGDWQAESRVQGKLSETSHESEPDSPHPIGGGGSLHMSQSYTTTPCYRPRSSSVPRFTYGSIPPRSESPFGTASSTCSSLRGGVESDAGIYHQRHRPAISPPETRAFLHEALDEVCSDFERTLERTSVKRRKSPYGAGSLSMDRNNNKLSLSISNGHGALKELKSHRLGNSTWDRHFDVADSCIGGNQSPTGTPRPFLRSNTLPLRQRPSPAEVQYESYVQATVAANAKSPVEQLESAKSPGAPPPPPPRRHHLLATTPTGKPTFKEDRPQENGSVSSSSLQSPVISETGQTTADAQALFQIREQMALSLRRLKDLEEQVKVIPDMELELNSLRSEKQKLLRRNEELMRSQRQTPSPPSPGLKTASPVQFTPQRISPVSLESLGARMRSSSTSASPSPSVVRRDVSTQAVVRPPATRDVSVGHQPTTRNVGVQPSETVYSKEELDKKVEQALTNAQKQQLRKLISVGTQMYVPQRDQKDSGVQTTPERPKLKYHVGVTVKPATRENFTSCKPDVRHVGSSDDRLDDVLCEKCAVSKRSVACGPETPAEKVKPAPQMPGRSNTFSLGENETVSVVRKTIGCQTPVTLVLSSGSQTTTAVVRSTGAQVNPQQQHSGVQCATEQVSRQTDTKGLQRLTRSQTKAEQVSESVPRPTTRHTASNTDKVEEAEPAKVRTSHSACNTEEVRKRDVGCGDIVKPHISIACAANYCDSCKEAIQDLARGFSKASPTATRTGGAVRRSTSADSRIPRPKHLSSPSPVRKEFMRQNTYTLATPSPTPSPQVERKARLSSLQEKPPSVSSFQASEPLPESQSFIRQPQKDSLDLSLLGEDELIVREEKRVSISWSRDASPAPLMTSSGTTKSESPEQEPAMSSSSDSSPPIDVQIAQGARKKSSTPLKSSQSEGSQVTVIEQPATKAQLHQLAQADSEPRKKTELSQSLKDALKIINDSLLKKLGAKPISSQSLKSAKATIQDHWFTNSSTGKSDPHQVEDYLDYFESLSIPLLEYCVNLSDSNGNTAMHYAVSHGNFDVVSILLDSKVCDVNQMNNAGYTSVMLVSLAKLKQPAHRTVVERLFKMADVNIRAKKHCQTALMLAVSHGNGDMVNMLLDAGADINIQDEDGSTALMCAAEHGRVDVIKHLLSHPECDSLVTDVDGSTAFKIAWQAGHRDVGLLIYVHEQMLRSKLPNRGDATRSSLISPPRHKRQPSQ
Protein: Guanine nucleotide-binding protein alpha-5 subunit (Q20701)
Organism: Caenorhabditis elegans
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Interaction partners:
- Guanine nucleotide-binding protein alpha-9 subunit
- G Protein, Alpha subunit
- Guanine nucleotide-binding protein subunit beta-1
- Guanine nucleotide-binding protein subunit alpha
- Regulator of G-protein signaling rgs-2
- C2H2-type domain-containing protein
- Glycoprotein hormone subunit beta domain-containing protein
- Guanine nucleotide-binding protein subunit beta-2
- Mitogen-activated protein kinase pmk-1
- G protein gamma domain-containing protein
Sequence:
MGLVTCKQEREAELQNRQIDTQIRIENQANKRKIKMLLLGVTDSGKSTIVKQMRVNYLDGFNETEVVNAIFVIRNNIIDAFKNICNIILHSDITVTQEEKVLVKLFAYESGKIELMQEVDELNVINAVSGYECIKQFFERFAFHPMVPDHIHYFYPNLDRIASSNYVPTAEDLIHMRQTTLGVHEISFDYTKHIIRLIDVGGQKTERRKWIHFFEGVTAVMFVCSLASFNQTTEEEPKAFVWESSLNKVQNKVLVRSAGKAKVEKPGLINRLDESVDLFKSIRENSFLKMSNFMLFLNKKDLLTKKLTKVVFSDYFPDYKKWITNDNSDVSVAEFIENMFREGLEPEKRMYAHLTQATVTANIEGTFALCCDVIFGKNYEDTNLE
Protein: Replication-associated protein (Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.-) (ATP-dependent helicase Rep) (RepP) (Q805H4)
Organism: Porcine circovirus 1 (PCV1)
Function: Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep and/or Rep' binds a specific hairpin at the genome origin of replication. Introduces an endonucleolytic nick within the conserved sequence 5'-AGTATTAC-3' in the intergenic region of the genome, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, and nucleotidyl transferase.
Subcellular location: Host nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MPSKKSGPQPHKRWVFTLNNPSEEEKNKIRELPISLFDYFVCGEEGLEEGRTPHLQGFANFAKKQTFNKVKWYFGARCHIEKAKGTDQQNKEYCSKEGHILIECGAPRNQGKRSDLSTAVSTLLETGSLVTVAEQFPVTYVRNFRGLAELLKVSGKMQQRDWKTAVHVIVGPPGCGKSQWARNFAEPSDTYWKPSRNKWWDGYHGEEVVVLDDFYGWLPWDDLLRLCDRYPLTVETKGGTVPFLARSILITSNQAPQEWYSSTAVPAVEALYRRITTLQFWKTAGEQSTEVPEGRFEAVDPPCALFPYKINY
Protein: Uncharacterized HTH-type transcriptional regulator YeiE (P0ACR4)
Organism: Escherichia coli (strain K12)
Interaction partners:
- UPF0324 inner membrane protein YeiH
- HTH-type transcriptional regulator HdfR
- HTH-type transcriptional regulator XapR
- 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN
- Lysine-specific permease LysP
Sequence:
MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNYILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYCDPANVPR
Protein: Tyrosine-protein kinase (EC 2.7.10.2) (A0A8I6AJU1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQYLNIKEDCNAMAFCAKMRSFKKTEVKQVAPEPGVEVTFYLLDREPLRLGSGEYTAEELCIRAAQECSISPLCHNLFALYDESTKLWYAPNHIITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELSRCHSNDSGNVLYEVMVTGNLGIQWRQKPNVLPVEKEKNKLKRKKLDYNKHKKEDDRNKLREEWNSFSYFPEITHIVIKESVVSINKQDNKNMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVSCFEKSEVLGNQKQFKNFQIEVQKGRYSLHGSVDHFPSLRDLMNHLKKQILRTDNISFVLKRCCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGTLLDYKDDEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKQPITEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDFSPMAVSVNCYLLNGVWSVCHVERVTACYLARSGKVCLHK
Protein: Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2) (Q9Z204)
Organism: Mus musculus (Mouse)
Function: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P07910}. Note=Component of ribonucleosomes. {ECO:0000250|UniProtKB:P07910}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein M
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Heterogeneous nuclear ribonucleoprotein A3
- Poly
- CUGBP Elav-like family member 1
- Serine/arginine-rich splicing factor 3
- RNA binding motif protein, X-linked-like-1
Sequence:
MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVPEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSSKSGKLKGDDLQAIKKELTQIKQKVDSLLESLEKIEKEQSKQADLSFSSPVEMKNEKSEEEQSSASVKKDETNVKMESEAGADDSAEEGDLLDDDDNEDRGDDQLELKDDEKEPEEGEDDRDSANGEDDS
Protein: GrpE protein homolog, mitochondrial (dRoe1) (P48604)
Organism: Drosophila melanogaster (Fruit fly)
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000305}.
Interaction partners:
- Heat shock 70 kDa protein cognate 5
- Mitochondrial import inner membrane translocase subunit TIM44
- Lon protease homolog, mitochondrial
- 10 kDa heat shock protein, mitochondrial
- 10 kDa heat shock protein, mitochondrial
- Uncharacterized protein, isoform C
- Cytochrome c oxidase subunit 5B-like
- Cytochrome c oxidase subunit 5B, isoform A
- ATP-dependent Clp protease proteolytic subunit
- Heat shock 70 kDa protein cognate 2
Sequence:
MSAKAALPLQMFGRRLVHLRSSVTSQNMSALRLYSTEKQPEEATEQKATESSPEVEKLTKELAAAKEQNAELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKDLLEVADTLGHATQAVPKDKLSGNADLKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFDPNQHEALFQKEDKTVEPNTVVEVTKLGYKLHERCIRPALVGVSKC
Protein: Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase) (Q8JI32)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
LIPAAMFRDPFRKDPNKLVLCQVLKYNRKPAETNLRRMCKKIMEMVENQVPWFGMEQEYTILGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVQICGTNAEVMPAQWEFQVGPCEGINMGDHLWAARFILHRVCEDFGVVASFDPKPIPGNWNGAGCHTNFSTKEMREDGGLRAIEESIEKLGKRHRYHICAYDPKGGLDNARRLTGHHETSNIHEFSAGVANRGASIRIPRSVGQDKKGYFEDRRPSANCDPYAVTEAMIRTCLLSEVGEEPTEYSK
Protein: Uncharacterized transcriptional regulatory protein C15D4.02 (O74308)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Galactose-specific cell agglutination protein gsf2
- MADS-box transcription factor pvg4
- Serine/threonine-protein kinase oca2
- Transcription factor cbf11
- Transcription factor cbf12
- Uncharacterized transcriptional regulatory protein C2H10.01
Sequence:
MEYHPSSQSPQVNPGMESQQGGYTYTYQQPAPPNSLHLQHPSILTRLPPLSSSVVSPSLASLPPFTPTSTYHSIAALTPPSYPQSSSAPSNNSYTIVPSPHDPSNAYSMHHVLQNTAPQSVPSPSPIEMVPPSPPKTGSNNSAPVTGKTVQSGNALNNSGLVKRQARKRTKTGCLTCRKRRIKCDERKPICYNCIKSKRQCEGYTHFPRPSGTFTASRRIPVSSLLSEPAPHGLAGQPTHPTFLYYIQSVAPSLCLWDACHFPPLSPYSSFSSIYWSSTVPELALRNPNISVALYAFASAKRHLTDDAVAFARQARVALTNITTTDSLLILVLLAVTQLYIPKSDIQLFNFAVDQVVKFDASLMTSPSDEIITYLLRRMFIRQVVLAGIVKPLASGLNPLPLLKCDLPPATTPTAVLDESLFHLGLRKLCHEKGLEPEFTKWSKNCPIDKADLPRLALLMIHAVFTSPVSLAQWVELILQNPDPTPAIHIARACLLAVHGVVDLGDLQMKVEKCVQSCEERQLQATISNFSTEVAQTNSSALAIGCQ
Protein: Anoctamin (A0A8I5ZT68)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU280814}.
Interaction partners:
Sequence:
IVREVCHWILNLEQEHFYVCLLYLLIPPHPSGDVPDSRRPFLAPHTPLPSGLVLENFDQTIVCSTFGSLESQEDFRTPEFEEFNGKPDSLFFTDGQRRIDFVLVYEDESKKENNKKGTNEKQKRKRQAYESNLISHGLQLEATRSVSDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKTRSTFDTFNWFTKVLRVNESVIKPEQEFFTAPFEKSRMNDFYILDRDSFFNPATRSRIVYFILSRVKYQVMNNVNKFGINRLVSSGIYKAAFPLHDCKFNYKSEDPNCPSERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCDPDIGGQILMCPQCDRLCPFWRLNITCESSKEEERIPFTTCGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQMATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRYKRVSGSEKITPRWEQDYHLQPMGRLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKNTDKENPYIGLVRLSFTVLNQKICLLTCLVVLPGTVTSETHPGTHKSINTTSTIGT
Protein: Coronin (G8G223)
Organism: Sus scrofa (Pig)
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Cytoplasmic vesicle, phagosome membrane {ECO:0000256|ARBA:ARBA00004580}.
Interaction partners:
Sequence:
MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLSKTGRVDKNAPMVCGHTAPVLNIAWCRHNDNVIGSDSEDCTVMVWEISDGVLTLPLREPVVTLEGHIKRVGIVAWHPTAQNVLLSAGCDNVILVWDVGTGAAVLTLGSDVHPDTIYSVDWSRDGALICTSCRDKRVRIIEPRKGTIVAEKDRPHEGTRPVRAVFVSDGKILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQEDLYPPTAGPDAALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDIGRRRTTPEASGAPSSDAIPRLEEEMEKLQATVQELQKRLDTLEETVQAK