wanglab/gogpt-training-data huggingface dataset:
Protein: Serine protease inhibitor 77Ba (Serpin 77Ba) (Q0E8C8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Serine protease inhibitor which plays an essential role in regulating the tracheal melanization immune response to bacterial and fungal infection. Acts by negatively regulating a protease cascade involving Mp1 and Sp7, that functions in the activation of the Hayan-phenoloxidase (PPO1) cascade.
Subcellular location: Secreted, extracellular space {ECO:0000269|PubMed:18854145}. Note=Detected in the extracellular space at the apical surface of tracheal cells. {ECO:0000269|PubMed:18854145}.
Interaction partners:
- Serine protease inhibitor 28Dc
- Serine protease inhibitor 27A
- Male accessory gland protein
Sequence:
MGKIADCLMLWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPMEVDFYSPDSVIQINEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNPKAA
Protein: Zinc finger protein 219 (Zinc finger protein 219-like) (F1QQA8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional regulator. Recognizes and binds to the core DNA sequence motif 5'-GGGGG-3'. Binds to the col2a1a promoter and activates col2a1a expression. Binds to the sncgb promoter and activates sncgb expression, as part of a complex with sox9a.
Subcellular location: Nucleus {ECO:0000305|PubMed:24155663, ECO:0000305|PubMed:24269816}.
Interaction partners:
- Bloodthirsty-related gene family, member 12
- Rho guanine nucleotide exchange factor
- Zinc finger protein 521.
- AT-rich interactive domain 5A
Sequence:
MDSPPECMLALSCEPPLSPPSMPSLDHSPQFLPQSPQSTPSSPQTELYAPVSPCPLPEASLQDEEEEDEELSTPPSPTPAVALFPGELELGSPSSESSPPATPLAPFPSFGALEKAISSGQSTTCNDELDLQLFNNESIAVTGGTSSGPGLRFPCHVCGKRFRFQSILSLHARAHSLDRERRASAPYRTTHSKLQQNHESNSMIQNPLSGSFQKSMNEDMVPEEPLQTASSPQFLFEGTTALTPPLTEEAPISTSFSPLGHAQLEDNTPSPAAPAFRCHACKGKFRTASELARHVRILHNPYKCTMCPFSASQEERLAAHLQESHPPEDPPAEAVFPSGAIKAPPETPVPQMSVIPAFRCETCGQRFTQSWFLKGHMRKHKDSLDHKCQVCGRGFKEPWFLKNHMKVHLNKLGLKAGLGNLGPPGADQSKGPASSQVLGALYSNLLLARSMAGGGGSGSRTERSDASAGSSKSSILGYLGLPKDSSNGSCMERLQAVAQVAEMGNGGGRGGDSADGADQAAMWQLVARSLVAAQHNQQQQQQQRSHSLHQHPSSRATVAGEAKNMRAYLGGLGSREELDGSSAPWECPDCGKLFRSLQQVVAHAHVHVQKTQKGQSARGGMSREEDIINRVSGTQATGGAGQRTGENESRQEGKQLPSGVGASGSFHSVISHLSGQNGLRGSSPSSSSPRERVRGTGMKDCPYCGKAFRSSHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRNAMATSPNSPSPSLPSLTGSPREGAKKRRLPSMSQQSSFGRVPGEAPSSRHTQSWTIGLSEKKEGSSASAHHREGDLESQYRGLSGMMGALLPSGLEQSWIGEVTLPKVPKVSRRKPQITSRMVSANGFQDKMTSQEGGFEPLDLSRRPLQDEGGVSQSGSGPSSGSKGGNDILNQCVFCPFRTSSVELMAMHLQVNHTSKSRRKRGAPISSNNHSQKLARPDRDPLALWKFLGVEDGVASPEDWVSARAENGVSPENRETEDNLELASGAMGSFRSRKKKPQMSEHVDEEDEEIDEEENDLEANGSFANVPQNQSRRAQSVSSDLPDDDLPKEEEGVLGE
Protein: Immunoglobulin heavy constant alpha 2 (Ig alpha-2 chain C region) (Ig alpha-2 chain C region BUT) (Ig alpha-2 chain C region LAN) (P01877)
Organism: Homo sapiens (Human)
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. Ig alpha is the major immunoglobulin class in body secretions.
Subcellular location: [Isoform 1]: Secreted {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
ASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDASGDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNSSQDVTVPCRVPPPPPCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGATFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAQPWNHGETFTCTAAHPELKTPLTANITKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTYAVTSILRVAAEDWKKGETFSCMVGHEALPLAFTQKTIDRMAGSCCVADWQMPPPYVVLDLPQETLEEETPGANLWPTTITFLTLFLLSLFYSTALTVTSVRGPSGKREGPQY
Protein: Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] (P80457)
Organism: Bos taurus (Bovine)
Function: Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species.
Subcellular location: Cytoplasm {ECO:0000250}. Peroxisome. Secreted.
Interaction partners:
- Purine nucleoside phosphorylase
- Butyrophilin subfamily 1 member A1
- Uricase
- Guanine deaminase
- Thiopurine S-methyltransferase
- Cytochrome P450 1A
- Hypoxanthine-guanine phosphoribosyltransferase
- Arylamine N-acetyltransferase 1
- Hypoxanthine phosphoribosyltransferase
- Purine nucleoside phosphorylase
Sequence:
MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDRLQDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCCMNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISFGAACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISDLNPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSAFKQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWNEKLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDSKDKCGKLDPTYTSATLLFQKDPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRYENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTVTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDLKKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKMLGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGRLCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRLEGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAASVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTGAPGNCKPWSLRV
Protein: Dipeptide permease D (P75742)
Organism: Escherichia coli (strain K12)
Function: Probable proton-dependent permease that transports dipeptides.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSFLYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGYAQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVLLVATPALITILFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFFSMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKESVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAELFIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINYSINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES
Protein: Mediator of RNA polymerase II transcription subunit 27 (Mediator of RNA polymerase II transcription subunit 3) (Q8RWM3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 32
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 9
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 8
- ATP-dependent DNA helicase Q-like 2
- Mediator of RNA polymerase II transcription subunit 23
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 22b
Sequence:
MQTLHQSQLLQNPAEAANNQSESDAPPKQVAQAMERLNQAARVIADIRLGADRILEAMFVASQPRHTDMPLQLFLREDASMRQHLQDLRLIGKKLEESGVLTESLRSRSNSWGLHMPLVCPDGAVVAYAWKRQLAGQAGASAVDRTRLALKAFTDQKRRFFPHIDDGLKMEPSSKKHRASHLLLENGREEPVDYKTLPDIQSRLEKLVPSVKVSTYGRLNWLKRANSLPGSGSDDPTEASKPIFQSSSKLRSGLQTEVVDKIAVIELSFPSLFRAIVSLSPAGSVDPDAVAFFSPDEGGSYLHARGFSVYHVYKHITEHAATALQYFLGFGTGTALYSLLLWICSFESVFSKPCTKCGRLLAMDKKSALILPPLHRAYQELPLALNLDVCEAYHSSCSQDDT
Protein: Vacuolar protein sorting-associated protein 17 (Carboxypeptidase Y-deficient protein 21) (Vacuolar protein targeting protein 3) (P32913)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Plays a role in vesicular protein sorting. Required for the sorting and delivery of a subset of soluble vacuolar hydrolases. Required for retention of late Golgi membrane proteins and vacuolar biogenesis. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The VPS5-VPS17 subcomplex may assemble onto the membrane to promote vesicle formation.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:9700157}; Peripheral membrane protein {ECO:0000269|PubMed:9700157}; Cytoplasmic side {ECO:0000269|PubMed:9700157}. Note=Membrane-associated on the cytoplasmic side of either the Golgi complex or an intermediate in Golgi to vacuole transport. {ECO:0000269|PubMed:9700157}.
Interaction partners:
- Carboxypeptidase Y-deficient protein 8
- Vacuolar protein sorting-associated protein 35
- Vacuolar protein sorting-associated protein 5
- Vacuolar protein sorting-associated protein 29
- Sorting nexin-3
- Sorting nexin-4
- Vacuolar protein sorting/targeting protein VPS10
- Sorting nexin MVP1
- Sorting nexin-41
- Autophagy-related protein 20
Sequence:
MTSAVPYDPYDDLDNNPFAEPQEEDSEPAATTTDGSSSMSEERVGTEQTAASVQDNGTANNIQNGLGEEGNATRSKTSNEHNENQQPSQPSERVILPERSDEKKKYTLLAKVTGLERFGSATGKKENPTIIFDCSTNLPTFRKQQYKNVKKSYEEFHQLFKYLNVAIQESFVPTLPSAYTTFGINSEEDRMKVTRNFQLWFNRLSQDPLIIRNEEVAFFIESDFNTYTPINKSKSLASGLKRKTLKQLAPPYDEITELAEFRPLVKSIYVVSQSLQEKLLRVSRNRKMMVQEENAFGQDFVNLDEHNKLYRRYGKILTAVGDIDSIIATMDMATLYDGLEWIVRDAYAVKEALTNRHFIMRNLVQAQQNSKAKQEQARRFRSRRDINPMKIDEALRQLKAAAKNEQVLTLKLQRITSNMIIERKQWISWYEEWIRSSIKEFTLRKIEYERKKLTLLERVRSDIRKADENGGLSRLGRHAVSNNNSDTSQTLKGDSWTGESNRKSQIPINKIAHTEFDDELFTEDDGYNSQDSDTTSLNARHAASLLGMSTK
Protein: SRA stem-loop-interacting RNA-binding protein, mitochondrial (Q9GZT3)
Organism: Homo sapiens (Human)
Function: RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16762838}. Nucleus {ECO:0000269|PubMed:16762838}. Note=Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters.
Interaction partners:
- Leucine-rich PPR motif-containing protein, mitochondrial
- SNW domain-containing protein 1
- Small nuclear ribonucleoprotein G
- NADH dehydrogenase 1 beta subcomplex subunit 2, mitochondrial
- Poly
- Cytochrome b-c1 complex subunit 8
- Mitochondrial import receptor subunit TOM7 homolog
- G-rich sequence factor 1
- NADH dehydrogenase 1 beta subcomplex subunit 4
- 2',5'-phosphodiesterase 12
Sequence:
MAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVKVQVHTRRPKLPQTSDDEKKDF
Protein: Putative uncharacterized mitochondrial protein AtMg00280 (ORF110a) (P93292)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
- Biotin carboxylase, chloroplastic
- Ribulose bisphosphate carboxylase small subunit 1A, chloroplastic
- Ribulose bisphosphate carboxylase small subunit 1B, chloroplastic
- Ribulose bisphosphate carboxylase small subunit 3B, chloroplastic
- Ribulose bisphosphate carboxylase small subunit 2B, chloroplastic
- 4-hydroxyphenylpyruvate dioxygenase
- Pentatricopeptide repeat-containing protein At4g19191
- Embryonic abundant protein-like
- EMBRYO DEFECTIVE 3147
Sequence:
MNNAAKRADCWFGAKNYGRAVYECLRGGLYFTKDDENVNSQPFMRWRDRFLFCAEAVYKAQAETGGIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLNRGIHRKY
Protein: Fructose-bisphosphate aldolase (EC 4.1.2.13) (Q9CED4)
Organism: Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Interaction partners:
Sequence:
MAIVSAEKFVQAARDNGYAIGGFNTNNLEWTQAILRAAEAKKTPVLIQTSMGAAKYMGGYKMCKLLIETLVESMGITVPVAIHLDHGHFDDALECIEVGYSSLMFDGSHLPIEENLKLAEEVIAKAHAKGISVECEVGSIGGEEDGIVGEGELAPIDDAVAMAKLGVDFLAAGIGNIHGPYPENWKGLHIDHLEKLNKALVEAMGHNVPIVLHGGSGIPDDQIREAIANGVAKVNVNTECQLAFAAATRKFVNEFDANEAEYMKKKLFDPRKFLKPGFDAITASVEERIDVFGSANKA
Protein: Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (Phosphotyrosyl phosphatase activator) (Q8ILG3)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU361210}.
Interaction partners:
- Protein phosphatase PP2A regulatory subunit A, putative
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Type 2A phosphatase-associated protein 42, putative
- Leucine carboxyl methyltransferase 1
- Phosphatase 2A regulatory subunit-related protein, putative
Sequence:
MGDVNSLSYKIINDESIIRFTKSSIYNDIIEFITNLNKSVVGVEMKPLEDFKLCNENDMINNDNFLFLSKNVYNIFQLIKNMNKCIDSCPPINQSSRFGNRGFQHFCDAYYKEVDEYLPHALSESNIPNISEHTYQISYYLKNSIGNKKRIDYGTGHELNFLLFLFCLNKINFFIPSDYKHLVLVLYRQYLEGVRRVQIIYTVEPAGSRGAWGLDDFQFLVFLFGAAQLSYNRKIKTDDIEKKELLELWAPKYLYFDALKYISMIKHAPFHESSQMLYDISGVETWEKICNGLLKMYQAEIIQKRQILQHILFGNLIDF
Protein: Mitochondrial fission factor (C9JHF5)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|RuleBase:RU368040}; Single-pass type IV membrane protein {ECO:0000256|RuleBase:RU368040}. Peroxisome {ECO:0000256|RuleBase:RU368040}.
Interaction partners:
Sequence:
MAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNADLEQGFQEGVPNASVIMQVPERIVVAGNNEDVSFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQN
Protein: RE62284p (Q8MS15)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MIPKKTTVKDSHIVKIAVEREDHIAQLIYLDQRHPLASKIQEICNGWSISDHQNYALQFYEPTNRKYVTEKNRNEIKNGSVLQLQYSPSKTACDAMEVLLNGSPQEKALRLKELTSLSTDHTFALEFIKEKGLDTLIKMIEDGGQTNEDILKYSLASFVELMEHGTVSWEVPENSFVARNIEIVRNFQKYPTNCGESALSNLENIVMCSNKHVLVAEDIKLQDILRLLQDVNSPVMRQNAIALLNALFVKADEGRRRTIAQTISAKQFRLALIGNGLGTEMTHQLYVLQTLTLGLLEKRMRMKMNAQDQDAHEKIKELRRIAFDDNTNALNQNDDHIRRGGGSGAGNVNFSQYYKKLGFKCDINPAQDFIETPPGILALDCMVYFARNYTQQYAKIVRENSCRADEHECPFGRTSIELVKVLCDILRIGEPPAEQSGDFQPMFFTHDSPFEEFFCICVITLNRTWKDMRATAEDFSTTFSVVREQIQRTLKGRPENLDDFRNKIALLTYQQITTLRQQERTSKEECDSTASAIVKLKEKISPQILELIKQQRLSFLVEGTHFAKYLRGTRTKDKFWYARLSPNHKVIHYGDCDEKTIPTMEELPKKLPISEIKQLLEGKECPHMKETRIRKSAVNLAFSITFENMEHSTLDFVAPDESIFNYWTDGINALLGQPMVSKQKNEDFDTLLSMEIKLRLLDTEGVDISKDPPPIPEDPENYDFCFES
Protein: N-acetylmuramoyl-L-alanine amidase AmiD (EC 3.5.1.28) (P75820)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- UPF0145 protein YbjQ
- Anhydromuropeptide permease
- Murein tetrapeptide carboxypeptidase
- Putative D-alanyl-D-alanine carboxypeptidase
- Thiamine-phosphate synthase
- N-acetylmuramoyl-L-alanine amidase AmiC
- N-acetylmuramoyl-L-alanine amidase AmiB
- Beta-hexosaminidase
- Soluble lytic murein transglycosylase
Sequence:
MRRFFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGISAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKPENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASLLELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
Protein: Large ribosomal subunit protein uL13A (60S ribosomal protein L16-A) (L13a) (L21) (RP22) (YL15) (P26784)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL15
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein eL14B
- Large ribosomal subunit protein eL8B
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL6A
- Large ribosomal subunit protein uL6B
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein eL29
Sequence:
MSVEPVVVIDGKGHLVGRLASVVAKQLLNGQKIVVVRAEELNISGEFFRNKLKYHDFLRKATAFNKTRGPFHFRAPSRIFYKALRGMVSHKTARGKAALERLKVFEGIPPPYDKKKRVVVPQALRVLRLKPGRKYTTLGKLSTSVGWKYEDVVAKLEAKRKVSSAEYYAKKRAFTKKVASANATAAESDVAKQLAALGY
Protein: Kunitz type trypsin inhibitor 104 (A0A072TH68)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Protease inhibitor involved in the control of mycorrhiza establishment and arbuscule development during root colonization by arbuscular mycorrhizal (AM) fungi (e.g. Rhizophagus irregularis).
Subcellular location: Secreted {ECO:0000269|PubMed:23662629}. Secreted, extracellular space, apoplast {ECO:0000269|PubMed:23662629}.
Interaction partners:
Sequence:
MSTRSLTIFILAHVWLLMATTSIAQFVIDTSGEPVEDDEEYFIRPAITGNGGGSTLVTGNGPCPLHVGLDNTEGTLGVAVKFTPFAPQHDDDDVRLNRDLRVTFLTSTSCGQSTDWRLGEKDATSGRRLIVTGRDNGAGSQGNFFRIVQTQTGGTYNIQWCPTEACPSCKVQCGTVGVIRENGKNLLALDGDALPVVFQKE
Protein: Adenosylhomocysteinase (EC 3.13.2.1) (Q383X0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cystathionine beta-synthase, putative
- 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
- Homocysteine S-methyltransferase, putative
- Kynurenine aminotransferase, putative
- DNA
- Homoserine kinase, putative
- Elongation factor TU, putative
- Inositol 1,4,5-trisphosphate receptor
- Farnesyl pyrophosphate synthase
Sequence:
MTDYKVRDISLAEWGRRELELAENEMPGLMELRREYGPSKPLKGAKIAGCLHMTMQTAVLIETLVELGAEVRWASCNIFSTQDHAAAAIAKRGIPVFAWKGETEEEYMWCMKQTLKGFSGDGYPNMLLDDGGDLTNYVLDECKELDGKIYGVSEETTTGVKNLYKRLQRGKLTIPAMNVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKTACVCGYGDVGKGCAAALRGFGARVVVTEVDPINALQAAMEGYQVLLVEDVVEEAHIFVTTTGNDDIITSEHFPRMRDDAIVCNIGHFDTEIQVAWLKANAKERVEVKPQVDRYTMANGRHIILLAEGRLVNLGCASGHPSFVMSNSFCNQVLAQIELWTNRDTGKYPRGAKAQVYFLPKKLDEKVAALHLGKLGAKLTKLTPKQAEYINCPVDGPFKPDHYRY
Protein: Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14) (E9QDB5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU365082}.
Interaction partners:
Sequence:
MAPVQIGSDGQLVPAGGPTSTPQPPPGAPATQGVRLSLLIEFLLQRTYHEITLLAELLPRKTDMERKIEIVQFASRTRQLFVRLLALVKWASNAGKVEKCAMISSFLDQQAYLFVDTADRLASLARDALVHARLPSFAIPFAIDVLTTGSYPRLPTCIRDKIIPPDPITKAEKQTTLNQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDIPWRLLKLEILVEDKETGDGRALVHSMQVNYIHELVQSRLFGDDKPLQDMYTCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYIPAKCLTLSVWNQQVLGRKTGTASVHKVTIKIDESDGSKPLQISHEPPLPACDSKLMERAMKIDHLSVEKLLIDSVHARSHQKLQELKAILKSSNPNDNSFIETALPTLVIPILEPCGRSECLHIFVDLHSGMFQPMLYGVDQSMLDDIEKSINDDMKRIVTWLLQLKFWLGEQRCRQSVKHLPTLCTDTLHLSNLTTHPVGNLSKHRLFIKLTRLPQYYIVVEMFDVPSNLTELQYKYYFLSVSQMESEDGLPSAQLFRHFKPNLEELVQDISSCRMVRPGTKRKLSGEQSAVEPKKPKRSGEMCAFNKELAHLVAMCDTNMPLIGLRSELSNMEIPHQGVQVEGDGCSHAIRILKVPPCMAVGEETRKALERSLLDCTFRLQGRNNRTWVAELIFSSCPLNSTSIKEQASTRHVYLTYENPLSEPVGGRKVVEMFLNDWNSISKLYECVLEFSRSLTEMPSYLSLFSEIRLYNYRKLVLCYGSTKGSSVTIQWNSVTHRYHLALGTVGPNSGCSNCHNIILHQLQEMFNKTPNVVQLLQVLSDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSPTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNTKIVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPISMEDTFMPHTQTQPPGRGVYPPLTSPPNPYHVPPSPSMITTQSPGTLDPSSPYTLVSASPRVGPWPGSPQVSGPSPGARIPGMSPGNPSLHSPIPDPSHSPRAGTSSQAMPPPRKLPQRSWAASIPTILTHSKLHVLLLPSPMPCPVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQLEPNLTIVNSNEPGVIMFKTEVLKCRVALNPKSYQTLQLKVTPENTGPWSQEELQVLEKFFETRVAGPPFKYNTLNAFTKLLGAPTNILRDCVRIMKLELFPDQAAQLNWNVQFCLTIPPSAPPIAPPGTIAVVLKTKMLFFLQLTQRLPVPQEPISIIVPIVYDMATGLTQQADIPRQHSSSGAAALMVSSILRRFNEHHPPRPGECTIFAAVHELMANLTLNSGGRP
Protein: Protein RER1 (O15258)
Organism: Homo sapiens (Human)
Function: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-exchange factor SEC12
- Gamma-secretase subunit PEN-2
- Surfeit locus protein 4
- ER lumen protein-retaining receptor 1
- B-cell receptor-associated protein 31
Sequence:
MSEGDSVGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWVVTLGLSFVYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTKQNEEFRPFIRRLPEFKFWHAATKGILVAMVCTFFDAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRRYRGKEDAGKAFAS
Protein: Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1) (Q9V3S0)
Organism: Drosophila melanogaster (Fruit fly)
Function: May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- Elongation of very long chain fatty acids protein
- Elongation of very long chain fatty acids protein
- AT07710p)
- Elongation of very long chain fatty acids protein
- Fatty acid desaturase domain-containing protein
- Fatty acid synthase
Sequence:
MAVEVVQETLQQAASSSSTTVLGFSPMLTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLENGFNVSLEKRQYATVA