wanglab/gogpt-training-data huggingface dataset:
Protein: ADP-ribosylation factor 5 (P84085)
Organism: Homo sapiens (Human)
Function: GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Subcellular location: Golgi apparatus {ECO:0000269|PubMed:17555535}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:17555535}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:P84084}; Lipid-anchor {ECO:0000250|UniProtKB:P84084}.
Interaction partners:
- Rab11 family-interacting protein 3
- Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
- ADP-ribosylation factor 4
- ADP-ribosylation factor 1
- Arfaptin-1
- Rab11 family-interacting protein 4
- Coatomer subunit beta
- Arfaptin-2
- IQ motif and SEC7 domain-containing protein 1
- Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
Sequence:
MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
Protein: HTH-type transcriptional regulator FL11 (Feast/famine regulatory protein FL11) (FFRP FL11) (O59188)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function: DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes. Binding sites are identified in promoters of approximately 200 transcription units, including genes involved in ATP synthesis, transmembrane transport, translation and DNA synthesis.
Interaction partners:
- 75aa long hypothetical regulatory protein AsnC
Sequence:
MRVPLDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFLDLIGSIPGVEGTHTMIVLKTHKETTELPIK
Protein: Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes) (Q5QHR8)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGRSSNRCCSGTGPPGVPTPHALGSRGITSEYRTLLQDRQHHSLRQGQLKSACKEEIPSEKTEEITAGSAWVSFLESHNTLHQDSTVSYTEHVFEISHCHDLLGMMVNLCAEDLRTGWDGHQAKQYL
Protein: Phosphoglycerate mutase (PGAM) (EC 5.4.2.11) (BPG-dependent PGAM) (MPGM) (Phosphoglyceromutase) (P36623)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Phosphoglycerate kinase
- Fructose-bisphosphate aldolase
- Enolase 1-2
- Enolase 1-1
- Glucose-6-phosphate isomerase
- Triosephosphate isomerase
- Pyruvate kinase
- ATP-dependent 6-phosphofructokinase
- Putative D-3-phosphoglycerate dehydrogenase
- Uncharacterized kinase mug58
Sequence:
MTTEAAPNLLVLTRHGESEWNKLNLFTGWKDPALSETGIKEAKLGGERLKSRGYKFDIAFTSALQRAQKTCQIILEEVGEPNLETIKSEKLNERYYGDLQGLNKDDARKKWGAEQVQIWRRSYDIAPPNGESLKDTAERVLPYYKSTIVPHILKGEKVLIAAHGNSLRALIMDLEGLTGDQIVKRELATGVPIVYHLDKDGKYVSKELIDN
Protein: Ribosomal protein L36a (J3KQN4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MIAPTDSHEEVRSGTSYILPFASRFLSFRADSAHASMVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF
Protein: AT07704p (Q8T4B0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLFSGNLDRSQQHGYFAGYYDKTPRVFYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPIEETPYKEIENYVSTTFMVSPPLATQQVMWTLHQLEKVYSGPAAAGENITVWSRPHLAEKLAKVPEMTPNLFSKYETLFAYPLPKGPDWGGKVDHVVLPRYTEMYSGQGLMVYGEDIVDSGQNGLESLQETLAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTHPSKKKKKK
Protein: Kirola (allergen Act d 11) (P85524)
Organism: Actinidia deliciosa (Kiwi)
Interaction partners:
Sequence:
MDLSGKMVKQVEILSDGIVFYEIFRYRLYLISEMSPVNIQGVDLLEGNWGTVGSVIFFKYTIDGKEKTAKDIVEAIDEETKSVTFKIVEGDLMELYKTFIIIVQVDTKGEHNSVTWTFHYEKLKEDVEEPNTLMNFCIEITKDIETYHLK
Protein: Envelope glycoprotein L (gL) (Q3KSS3)
Organism: Epstein-Barr virus (strain GD1) (HHV-4) (Human gammaherpesvirus 4)
Function: The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. The heterodimer gH/gL targets also host EPHA2 to promote viral entry.
Subcellular location: Virion membrane {ECO:0000255|HAMAP-Rule:MF_04034}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_04034}; Extracellular side {ECO:0000255|HAMAP-Rule:MF_04034}. Host cell membrane {ECO:0000255|HAMAP-Rule:MF_04034}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_04034}; Extracellular side {ECO:0000255|HAMAP-Rule:MF_04034}. Host Golgi apparatus, host trans-Golgi network {ECO:0000255|HAMAP-Rule:MF_04034}. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans-Golgi where secondary envelopment occurs. {ECO:0000255|HAMAP-Rule:MF_04034}.
Interaction partners:
Sequence:
MRAVGVFLATCLVTIFVLPTWGNWAYPCCHVTQLRAQHLLALENISDIYLVSNQTCDGFSLASLNSPKNGSNQLVISRCANGLNVVSFFISILKRSSSALTSHLRELLTTLESLYGSFSVEDLFGANLNRYAWHRGG
Protein: Zinc finger protein 566 (Q969W8)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger protein 30 homolog
Sequence:
MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYLEQGKEPWLADRELTRGQWPVLESRCETKKLFLKKEIYEIESTQWEIMEKLTRRDFQCSSFRDDWECNRQFKKELGSQGGHFNQLVFTHEDLPTLSHHPSFTLQQIINSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYDPQLIQHQNLYW
Protein: E1 ubiquitin-activating enzyme (EC 6.2.1.45) (C1P636)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTTILELTSANKTNNKATNNKLQREGENEYPPAKRSKTDDEEEPTVVGNGTIVGAPKQQTLSGVNSGNVNVETTKNTEGQDGEKMDTSNNAGGVGGNSDELLDKNLYSRQIYTLGESAMVNLRTASVLISGLGSVGVEIAKNLILGGVRHVTIHDTKLAKWSDLSAQYYLRDADVGHNRATSCYERLAELNDSVNVQVSTDELTEEFVKTFDLVVLTDAARTAQRQIAAWTRAHNRRILITDARGVFSYIFNDFGDNFRIDDATGEQVREFFIEHIDKTTGEVTTLENLFHGLEDGDHVTFSEVKGLTEINGCEPLKITVKNASKFNIGDFAVSFSDYKEGGRCRQVKVPTSVSHVPFEKSLVEPEFGIWDYAKFEYPSQLHALWTALYAFEEKYGRSPAPRSTQDAALLKELIPSGTEEIPEKLIELFSFSASGNLVTVSSVVGGIAAQEAMKGVTHHMTPLKQWLHLDHVEVLPGDWTSFDNSKLSETDCQPRQSRYDGQAAVFGWPYQECLFRQRWFVVGAGAIGCELLKNLSMMGVACGEGGLIKITDMDQIEISNLNRQFLFRRRDVGGKKSECAARAVTAFNSDVRIEALAERVGLETEHIFNDEFFGELNGVANALDNVDARRYMDRRCVYYRLPLLESGTMGTKGNTQVVYPYLTESYSSSVDPPEKEIPVCTLKNFPNEIQHTIQWAREQFETFFAQPGEMANKFLSDERGFNEHVDKLISGQQIDILQKVKDALIDARPSSAEDCIRWARNQFQELYHNNIAQMLHSFPPDQLTDSGAKFWSGAKRCPHVLNFDPSKEEHFNFVFAASILIAELYGVQPILDREEVIRVALSVNPEPFEPKSGVKIAVTDAEAKEQNERGASSMIVDDDAAIEALKLKLATLNVKSTSKLNCVDFEKDDDSNHHMEFITAASNLRAENYDILPADRMRTKQIAGKIIPAIATTTAAVAGLVCIELYKVVDANGIPKTPMERFKNTFLNLSMPFFSSAEPIGAPKKTYMDREFTLWDRIDVQGPLTLQEFIDNVQNQTGGCEVSMLSAGACLLFSFFMNAGKKQERLKTEVKAVYEELLKKSLHPSVHALVLEPMMSDPDGEDVEVPYIRYSF
Protein: Toll-5 (Q9NBK8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MLTYLPVVWLFFALLVLRSATGQIIPLPTFCLGLSPQCTCAAEGNVVRFHCPDEYAMLLEVSEPGASLYMSYYASTELQWLPRFNISSLVKIEFDAYIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETSQPENITTWHFGSVPGLKKFKFFSHVPELQESIFHGFDTLRDLHLSVNVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIHPFHERDKQLQPHFFGSMTNLEEVRLASATSSVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLDLSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLSSTIFAPLTSLNVLRLNKNSLTAMSPSVFQDVVSLNYIEMVNTQFYGATLLMNYEAVVCTNDEACQYKSAEWQCDPRCICWVQRSVGSLIVDCRGTSLEELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSEEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLISCVVGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDKTYDAFISYSHKDEELISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSELRAYLKLNTYLKWGDPLFWSKLYYAMPHNRRVLKGQKKHAGPLI
Protein: Microtubule-associated protein (A0A0B4LHV0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU000686}.
Interaction partners:
Sequence:
MHLVIMADATYLLDRNGPNSPSSPVKTPTSTSSKPDKSGTSRPPSATPSNKSAPKSRSASKNRLLLKTPEPEPVKKVPMNKVQVGHAPSPNLKAVRSKIGSLDNATYKPGGGHVKIESKKIDIKAAPRIEAKNDKYMPKGGEKKIVTTKLQWNAKSKIGSLENAAHKPGGGDKKIETLKMDFKDKAKPKVGSTANVKHQPGGGDIKIQTQKLEIKAQSKVGSLDNVKHKPGGGEKKIFDDKDYLKNVEHSVALTTPPTQSPLPSMTASGADENLNQQS
Protein: ABC transporter A family member 7 (ABC transporter ABCA.7) (Q8T6J0)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKYNANTSNQFRAMFFKNATFLKRQKCSLGVQIAIPMALVIVLVILKLWIESQIENNSGPVGDSSGDDIMGSYISYKFDYMQGWFYTINPNNITNIGYKDGYGNGTGLLGGINQYEIYWNGSDLWVPYTVAVESGQKMNDMVLAQKQQLGQSSMGPLTFPIAGIQFNEFNPQNNLIDLTITCEQQIRYAYNNFENNLIYVLSQIQTSFINYLLNGNGVVVKTQISTLPYIYKSQQFDIASLLGGSFFPFALSFVLPLFMYSIVYEKQEKLRDLSLMMGLKMRNYWIMTFIFNFLTYVVIVSVISLICSAAKVSLFVKGSPFALFLLLFLWGLSMVSFAFFLSTFFKRTRAASIFGYFFVMVMVNLNSTLSLFNTSVPVFYYWVPILAFSRGISTLCGLCGNGLCPPLSQYTWDFELSRILFWLFIDTIVYLTLAVYLDKVLPREFGVPSHPLFFIKDLKELFSKKGKYRKLRDGDGINEKTKLINEYTIDGINNDDDDDGLMDEDVKKERDMIVKGEYNPEEMTLIVQGLRKQFPGRPKPALSNLYLSVKKGEVLGYLGPNGAGKTTSISILTGLYTPTSGTAHIAGLDIRYDMDKIHQVIGVVMQFDVLWEDLTCEETILYYTRLKGTPKSIEFESTHNILKEVNLLDVKDRFVKELSGGMKRRLSFAIAMTGESSIIFLDEPTTGLSIETRKDLWGTINELKKNRSIILTTHSMQEADILSDRIAIVSQGKLQCIGTQTHLKQKFGDGYSVRIDIQEDYQNTHNPTDLIKSFSPSATLSETFNGSYVYRLPKDSIISDLYEYLVLNKEQYHLQEWSLSQTSLEDVFLKISANDDTVN
Protein: Pheromone-processing carboxypeptidase KEX1 (EC 3.4.16.6) (Carboxypeptidase D) (Killer expression defective protein 1) (P09620)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from the precursors of K1, K2 and K28 killer toxins and a-factor (mating pheromone). Involved in the programmed cell death caused by defective N-glycosylation and contributes also to the active cell death program induced by acetic acid stress or during chronological aging. Promotes cell fusion by proteolytically processing substrates that act in parallel to PRM1 as an alternative fusion machine, as cell wall components, or both.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:1469044}; Single-pass type I membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:1469044}.
Interaction partners:
- Kexin
- Dipeptidyl aminopeptidase A
- Pro-apoptotic serine protease NMA111
- Protein KRE1
- Metacaspase-1
- Saccharopepsin
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3
Sequence:
MFYNRWLGTWLAMSALIRISVSLPSSEEYKVAYELLPGLSEVPDPSNIPQMHAGHIPLRSEDADEQDSSDLEYFFWKFTNNDSNGNVDRPLIIWLNGGPGCSSMDGALVESGPFRVNSDGKLYLNEGSWISKGDLLFIDQPTGTGFSVEQNKDEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAILNHNKFSKIDGDTYDLKALLIGNGWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLTNAHENCQNLINSASTDEAAHFSYQECENILNLLLSYTRESSQKGTADCLNMYNFNLKDSYPSCGMNWPKDISFVSKFFSTPGVIDSLHLDSDKIDHWKECTNSVGTKLSNPISKPSIHLLPGLLESGIEIVLFNGDKDLICNNKGVLDTIDNLKWGGIKGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVSRGIVDIYSNDVMIIDNNGKNVMITTDDDSDQDATTESGDKPKENLEEEEQEAQNEEGKEKEGNKDKDGDDDNDNDDDDEDDHNSEGDDDDDDDDDEDDNNEKQSNQGLEDSRHKSSEYEQEEEEVEEFAEEISMYKHKAVVVTIVTFLIVVLGVYAYDRRVRRKARHTILVDPNNRQHDSPNKTVSWADDLESGLGAEDDLEQDEQLEGGAPISSTSNKAGSKLKTKKKKKYTSLPNTEIDESFEMTDF
Protein: 2OG-Fe dioxygenase family protein (Q5FQD2)
Organism: Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Interaction partners:
Sequence:
MNPTDLSPPFDRVLTGVEDTLLEKGFSFLQADVTRPLLEHEGLTDWQGFAESWNHLGLDRYMADGGRYRRRRYATFAVSGDTITRKKHQPHYQSRDYNLLNGGIERWFPAVTDAIATHPAMTAAIRTVSRIADALTPPKEKPPVWHVEVHQFRIEARPGNEGHPTPEGLHRDGVDWVLVLMVARHNVEQGVTTIHGMRKEPLGSFTLTNPLDAAIVDDHRVYHGVTAVQPVDPSQPAYRDVLVVTLRHE
Protein: Myc proto-oncogene protein (Proto-oncogene c-Myc) (Transcription factor p64) (P09416)
Organism: Rattus norvegicus (Rat)
Function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (By similarity). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:P01106}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P01106}. Nucleus {ECO:0000250|UniProtKB:P01106}. Cytoplasm {ECO:0000250|UniProtKB:P01106}. Note=Localization to the nucleolus is dependent on HEATR1. {ECO:0000250|UniProtKB:P01106}.
Interaction partners:
- Protein max
- Mitogen-activated protein kinase 3
- Glycogen synthase kinase-3 beta
- Catenin beta-1
- Mitogen-activated protein kinase 1
- Cyclin-dependent kinase 4 inhibitor B
- Sirtuin 6 6
- Myc box-dependent-interacting protein 1
- Cellular tumor antigen p53
- KLF transcription factor 4
Sequence:
MNFLWEVENPTVTTMPLNVSFANRNYDLDYDSVQPYFICDEEENFYHQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVATSFSPREDDDGGGGNFSTADQLEMMTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSTSLSPARGHSVCSTSSLYLQDLTAAASECIDPSVVFPYPLNDSSSPKSCTSSDSTAFSSSSDSLLSSESSPRATPEPLVLHEETPPTTSSDSEEEQDDEEEIDVVSVEKRQPPAKRSESGSSPSRGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCSSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQADEHKLISEKDLLRKRREQLKHKLEQLRNSGA
Protein: SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A) [Cleaved into: SUMO-activating enzyme subunit 1, N-terminally processed] (Q9UBE0)
Organism: Homo sapiens (Human)
Function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Subcellular location: Nucleus {ECO:0000269|PubMed:11481243}.
Interaction partners:
- SUMO-conjugating enzyme UBC9
- SUMO-activating enzyme subunit 2
- Small ubiquitin-related modifier 1
- Small ubiquitin-related modifier 2
- Ran GTPase-activating protein 1
- Sentrin-specific protease 1
- Small ubiquitin-related modifier 4
- E3 SUMO-protein ligase PIAS1
- MORC family CW-type zinc finger protein 3
- E3 SUMO-protein ligase RanBP2
Sequence:
MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
Protein: Paired box 7a (Paired box protein Pax-7a isoform PAX7D) (A0A0R4IM38)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MATLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGTVPSGEASSVSSISRVLRARFGKKDDDDECDKKDEDGEKKTKHSIDGILGDKGNRTDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPTYQLPESTYPSTTLSQDGSSTLHRPQPLPPSSMHQGGLSADSGSAYGLSSNRHTFSSYSETFMSPTASSNHMNPVSNGLSPQVMSILSNPSAVPSQPQHDFSISPLHGGLEASNPISASCSQRSDPIKSVDSLASTQSYCPPTYSATSYSVDPVTAGYQYSQYGQSTYCTVPASHSLYRAAFL
Protein: Protease Do-like 5, chloroplastic (EC 3.4.21.-) (Q9SEL7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable serine protease.
Subcellular location: Plastid, chloroplast thylakoid lumen {ECO:0000269|PubMed:11719511}.
Interaction partners:
- Protease Do-like 7
- Putative protease Do-like 6, chloroplastic
- Protease Do-like 4, mitochondrial
- Protease Do-like 9
- Putative Do-like 15 protein
- Glyoxysomal processing protease, glyoxysomal
- Putative protease Do-like 12, mitochondrial
- Protease Do-like 8, chloroplastic
- ATP-dependent zinc metalloprotease FTSH 1, chloroplastic
- ATP-dependent zinc metalloprotease FTSH 5, chloroplastic
Sequence:
MTMALASSKAFSSIFNTLSPINQSKFVLACSGSNHVDVIDRRRRIMIFGSSLALTSSLLGSNQQRLPMESAIALEQFKEKEEELEEEEERNVNLFQKTSPSVVYIEAIELPKTSSGDILTDEENGKIEGTGSGFVWDKLGHIVTNYHVIAKLATDQFGLQRCKVSLVDAKGTRFSKEGKIVGLDPDNDLAVLKIETEGRELNPVVLGTSNDLRVGQSCFAIGNPYGYENTLTIGVVSGLGREIPSPNGKSISEAIQTDADINSGNSGGPLLDSYGHTIGVNTATFTRKGSGMSSGVNFAIPIDTVVRTVPYLIVYGTAYRDRF
Protein: Glycosyltransferase (F4JJF6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MNQTRRKRRPDSSLSRLDSLSPEMLFPAKSPSLTSSRIRNIFLLLIFCFIIYIIFSYGTNFRREQISSIARSLSVFSTRRRHLLFSIAASHDSWLRRSSYVRLWYSPESTRAVVFLDRGGLESDLTLPPVIVSKDVSRFPYNFPGGLRSAIRVARVVKETVDRGDKDVRWFVFGDDDTVFFVDNLVTVLSKYDHRKWFYVGSNSEFYDQNVRYSFDMAFGGGGFAISASLAKVLAKVLDSCLMRYSHMYGSDSRIFSCVAELGVTLTHEPGFHQIDVRGNIFGLLCAHPLSPLVSLHHLDAVDPFFPKRNRTESVAHLIGAASFDSGRILQQSVCYDSLNTVTVSVVWGYAVQVYEGNKLLPDLLTLQKTFSTWRRGSGVQSNYMFSTREYPRDPCGRPLVFFLDSVGSDGTEGTWSNYNIHRVGHCHRAEAVERLERIRVLSPKLERNVEQMGLPRRQCCDISSPYNKSMVINIRQCMPDELIAMNT
Protein: Ankyrin repeat domain-containing protein 29 (Q8N6D5)
Organism: Homo sapiens (Human)
Interaction partners:
- Alpha-adducin
- Beta-adducin
- Gamma-adducin
- Alpha-globin transcription factor CP2
- Upstream-binding protein 1
Sequence:
MCRMSFKKETPLANAAFWAARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDGGTALLAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELLKFSPTLGILKNGTSALHAAVLSGNIKTVALLLEAGADPSLRNKANELPAELTKNERILRLLRSKEGPRKS
Protein: RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) (P25931)
Organism: Drosophila melanogaster (Fruit fly)
Function: Receptor for the neuropeptides RYamide-1 and RYamide-2. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. RYamide signaling may suppress feeding behavior.
Subcellular location: Cell membrane {ECO:0000269|PubMed:1370455, ECO:0000269|PubMed:21704020, ECO:0000269|PubMed:21843505}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- RYamide neuropeptides
- Myosuppressin receptor 2, isoform C
- Proctolin receptor, isoform A
- Myosuppressin receptor 1, isoform B
Sequence:
MEHHNSHLLPGGSEKMYYIAHQQPMLRNEDDNYQEGYFIRPDPASLIYNTTALPADDEGSNYGYGSTTTLSGLQFETYNITVMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLLLNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLRRWCCLRSVGDRMNATSGTGPALPLNRMNTSTTYISARRKPRATSLRANPLSCGETSPLR
Protein: DNA ligase (EC 6.5.1.1) (F5GZ28)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MQRSIMSFFHPKKEGKAKKPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRKAARVLGSEGEEEDEALSPAKGQKPALDCSQVSPPRPATSPENNASLSDTSPMDSSPSGIPKRRTEAETPTESVSEPEVATKQELQEEEEQTKPPRRAPKTLSSFFTPRKPAVKKEVKEEEPGAPGKEGAAEGPLDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDTY
Protein: Alpha-galactosidase mel1 (EC 3.2.1.22) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Q9URZ0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Secreted alpha-galactosidase required for catabolic conversion of melibiose to glucose and galactose.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000269|PubMed:16823372}. Secreted {ECO:0000269|PubMed:15580593}.
Interaction partners:
- Invertase
- Bifunctional protein gal10
- Putative invertase
- Alpha-glucosidase
- Uncharacterized family 31 glucosidase C30D11.01c
- Uncharacterized family 31 glucosidase C1039.11c
- Alpha-glucosidase
- Galactokinase
- Homoaconitase, mitochondrial
- Adenylosuccinate synthetase
Sequence:
MISISFLNCFFLVFLFLFFSDVHGSYNGLGLKPQMGWNSWNKYACDIDESIILNNAKAIKEEGLLDLGYEYIVMDDCWSKHERNATTGRLEANPDKFPNGIGSMAKKLHDMGFKFGMYSSAGKYTCAGFPGSLNHEQIDADTFADWGVDYLKYDNCFNEGKSGVPLISYERYKRMSDALNKTGRPIFYSLCQWGEDFVWNWGNTIANSWRISGDIFDTFSRKDVRCPCETIECFALQGDHCSVMNIISKASFLSSKAGMNSGWNDLDSLEVGNGGMSFEEYKTHFTMWAILKSPLILGNDVSSMSPMDKLIVSNKELISINQDIGTNPAALIWKKKYGDEYIELFSGRLSNNDWVVAVLNAASEPLKMGIHLSDIFVDALGNAEHDWLATDLWNNNVKLVSDRIRANVASHGVQVWRFQQYKVKNTNDKFFSFNKH
Protein: Phosphatase DCR2 (EC 3.1.-.-) (Dosage-dependent cell cycle regulator 2) (Q05924)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for cell cycle progression. Has a role in the completion of START.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15590836}.
Interaction partners:
- Polyol phosphate phosphatase PYP1
- Serine/threonine-protein kinase/endoribonuclease IRE1
- Protein phosphatase 2C homolog 2
- Phosphate system positive regulatory protein PHO81
Sequence:
MIRLPRLYQRYLLYLVVFVVIALFYFLQAPRVEEHIGFDLALPISHVDNLWFQNKGLEGFSNDDKLVVNIGYDECFHIGRFYEGCFNRHELKSTLTDGHQYLQRKRIHKDLRGSFGRRWFGKSEYLYYDVLYPALVDYFGSNLEKLNVEAVTGISKYPKDKSLPFMDVSITFEPISIELLQKRSYISDINILFGVDCIQPIANWTLQKEFPLVKYRYSEPAYLTYKFVGTRPVDTGAQRLQETDEGKFKIVQLADLHLGVGESECIDEYPKHEACKADPKTETFVQQVLDIEKPQLVVFTGDQIMGDRSIQDSETVLLKAVAPVIARKIPWAMVWGNHDDEGSLTRWQLSEIASVLPYSLFKFSPHDTHDNTFGVGNYIYQIFSNNDTEVPVGTLYFLDSHKYSTVGKIYPGYDWIKESQWKYIEDYHDVNLKFKTGLSMAFFHIPLPEYLNIESKTHPGEKNPLIGMYKEGVTAPKYNSEGITTLDRLSVDVVSCGHDHCNDYCLRDDSTPNKIWLCYGGGGGEGGYAGYGGTERRIRIYEINVNENNIHTWKRLNGSPKEIFDFQSMLDGNSPESV
Protein: Caspase 9, apoptosis-related cysteine peptidase (Caspase-9 (EC 3.4.22.62)) (F1QSB1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- X-linked inhibitor of apoptosis.
- Cytochrome c
- Apoptotic protease-activating factor 1
- Bcl-2-like protein 1
- Apoptosis regulator Bcl-2
- RING-type E3 ubiquitin transferase
- Poly [ADP-ribose] polymerase 1
- Caspase 6, apoptosis-related cysteine peptidase a
- Baculoviral IAP repeat-containing 5a.
- Uncharacterized protein
Sequence:
MEQKHRQILQRHRLNLVKALNPEDVCDKLLSKGVFTQDMIDEIQSKATRRDQARQLVKDLETRGSLAFPAFLDSLRETGHNDLAELLQSGDGVHRPPVISVQPSPIPLPVQNLNHTEKPDKPDIASPRLVPLRPESLPVHKTYSPPSETVVRPTRPRRDSIQCYKMDASPCGVCLIINNINFEKASELNDRKGSNIDCDKLEKRFKALNFEVTVKRNLKSKRIRHEMASLAKKDHSTYDCCVVIILSHGTEASHNRFPGAVHGVDGPAVPIQIITNYLNGQNCPSLQGKPKLFFIQACGGGEKDIGFEVSPDDVQPSIGGIDDEMDAIPMSSSSDSLSTASDELDARASLPTPSDILVSYSTFPGYVSWRDTEAGSWYVENLDRVLEENAITDDLVTMLMLVNDAVSQISAKGLYKQMPGSFNFLRKLLYFQSSQS