wanglab/gogpt-training-data huggingface dataset:
Protein: CsgBAC operon transcriptional regulatory protein (P52106)
Organism: Escherichia coli (strain K12)
Function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae-expressing phenotype, up-regulates 10 genes and down-regulates 14 others.
Subcellular location: Cell inner membrane {ECO:0000305|PubMed:16513732}; Peripheral membrane protein {ECO:0000305|PubMed:16513732}. Note=In experiments done with low-level constitutively expressed protein.
Interaction partners:
- Curli production assembly/transport component CsgF
- Curli production assembly/transport component CsgE
- Curli production assembly/transport component CsgG
- Minor curlin subunit
- RNA polymerase sigma factor RpoS
- Major curlin subunit
- HTH-type transcriptional regulator MlrA
- Probable diguanylate cyclase DgcC
- Diguanylate cyclase DgcM
- Curli assembly protein CsgC
Sequence:
MFNEVHSIHGHTLLLITKSSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
Protein: One cut domain family member 3 (One cut homeobox 3) (Transcription factor ONECUT-3) (OC-3) (O60422)
Organism: Homo sapiens (Human)
Function: Transcriptional activator. Binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00374}.
Interaction partners:
- Hepatocyte nuclear factor 6
Sequence:
MELSLESLGGLHSVAHAQAGELLSPGHARSAAAQHRGLVAPGRPGLVAGMASLLDGGGGGGGGGAGGAGGAGSAGGGADFRGELAGPLHPAMGMACEAPGLGGTYTTLTPLQHLPPLAAVADKFHQHAAAAAVAGAHGGHPHAHPHPAAAPPPPPPPQRLAASVSGSFTLMRDERAALASVGHLYGPYGKELPAMGSPLSPLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPAAFEPHAALLGRAEDALARGLPGGGGGTGSGGAGSGSAAGLLAPLGGLAAAGAHGPHGGGGGPGGSGGGPSAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEQQKERALQPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQVTISQQLGLELNTVSNFFMNARRRCMNRWAEEPSTAPGGPAGATATFSKA
Protein: Aldehyde dehydrogenase 1 (TcALDH1) (EC 1.2.1.5) (Trans-chrysanthemic acid synthase) (EC 1.2.1.-) (A0A2I7G3B0)
Organism: Tanacetum cinerariifolium (Dalmatian daisy) (Chrysanthemum cinerariifolium)
Function: Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide. Mediates the conversion of trans-chrysanthemal into trans-chrysanthemic acid. Can also use octanal, hept-2-enal, dodecanal, citral, farnesal, citronellal and perillyl aldehyde as substrates.
Interaction partners:
Sequence:
MSSGANGNSKSLAYDIKFTKLFINGEFVDSISGSTFETIDPATEEVLATVAEGREEDVDLAVKAAREAFDNGPWPRLSGEARRKILLKFADLIEENADEIATLEVIDTGKPFQIARYVENSWTSETFRYFAGAADKIRGATLKMSSDFQAYTLREPIGVVGHIIPWNAPAYLFAMKVAPALAAGCTVVIKPAENTPLVGLFMAYLSKLAGVPDGVINVVNGFGSTAGAAVSSHMDIDAVTFTGSTKVGRTIMQAAAASNLKPVSLELGGKSPFIVFDDADIEKAAEIAVLGVLSNKGELCVAGSRVFVHEGIYDAFVKKLEATVKNWATGDRFDAATRHGPQNNKQQYEKVLSYIELGKKEGATLVTGGKPFGNKGYYIEPTLFTNVTDEMTIAKEEIFGPVIMVLKFKTIEEVIRRANATTYGLAAGIMTKNIDIANTVTRSIRAGSVWVNCYLALDRDTPFGGYKMSGFGREQGLEALEHYLQVKTVTTPIYNSPWL
Protein: Wake-up-call, isoform A (Wake-up-call, isoform B) (A1Z949)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cookie monster
- LD06557p
- Lin-52, isoform A
- Always early, isoform A
Sequence:
MKKVTKSIKREGSPSDEEYTLEEDPIEFELEKMERGSSNGESEEESQRDQKQADSIIDDMVEQNDQEQEAAGEQDVERENDLRKMYELSLLPPAAIAAQIQQMEKEIYELSQWEARELIRSKHLRIFGNCRRRANK
Protein: Cathelicidin-derived antimicrobial peptide 1 isoform am (A0A0F6QGK3)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MKMKVQVRSLILLAVAVLQVRSRRSKVRICSRGKNCVSRLGGGSIIGRPGGGSLIGRPGGGSVIGRPGGGSPPGGGSFNDEFIRDHSDGNRFA
Protein: Pregnancy-specific beta-1-glycoprotein 3 (PS-beta-G-3) (PSBG-3) (Pregnancy-specific glycoprotein 3) (Carcinoembryonic antigen SG5) (Q16557)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Pregnancy-specific beta-1-glycoprotein 9
- Pregnancy-specific beta-1-glycoprotein 1
- Pregnancy-specific beta-1-glycoprotein 6
- Ankyrin repeat domain-containing protein 46
- Chorionic somatomammotropin hormone 1
- Pregnancy-specific beta-1-glycoprotein 11
- Pregnancy-specific beta-1-glycoprotein 8
- Chorionic somatomammotropin hormone 2
- Pregnancy-specific beta-1-glycoprotein 2
- Pregnancy-specific beta-1-glycoprotein 4
Sequence:
MGPLSAPPCTQRITWKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQNLAGYIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSFTYYHSGENLYLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGMESSKSMTVKVSAPSGTGHLPGLNPL
Protein: Non-secretory ribonuclease (EC 4.6.1.18) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (RNase 2) (Ribonuclease US) (P47784)
Organism: Pongo pygmaeus (Bornean orangutan)
Function: This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Possesses a wide variety of biological activities.
Subcellular location: Lysosome {ECO:0000305}. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Interaction partners:
Sequence:
MVPKLFTSQISLLLLLGLLAVDGSLHVKPPQFTWAQWFETQHINMTSQQCNNAMQVINNFQRRCKNQNTFLRTTFANVVNVCGNPNITCPSNRSRNNCHHSGVQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDPRRDPPQYPVVPVHLDRII
Protein: DNA 5'-3' helicase (EC 5.6.2.3) (K7EIT8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQ
Protein: Neurochondrin (Neurite outgrowth-related protein from the rat brain) (Norbin) (O35095)
Organism: Rattus norvegicus (Rat)
Function: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:10521593}. Endosome membrane {ECO:0000269|PubMed:23687301}; Lipid-anchor {ECO:0000305|PubMed:23687301}. Cell projection, dendrite {ECO:0000269|PubMed:10521593, ECO:0000269|PubMed:23687301}. Postsynapse {ECO:0000269|PubMed:23687301}. Note=Localizes to somatic regions of neurons (PubMed:10521593, PubMed:23687301). Localization to endosome membrane requires palmitoylation (PubMed:23687301). {ECO:0000269|PubMed:10521593, ECO:0000269|PubMed:23687301}.
Interaction partners:
- General receptor for phosphoinositides 1-associated scaffold protein
- Metabotropic glutamate receptor 5
- Metabotropic glutamate receptor 8
Sequence:
MSCCDLAAAGQLGKAGIMASDCEPALNQAESRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELASHPQVLNKIPILCTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQRAEDASKFELCQLLPLFLPPTTVPPECHRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPVGSSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSIMKEAIGAVIHYLLRVGPEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEASDISQQVANLAISPTTPGPAWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPSLVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQAVLALSPDYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP
Protein: IP03305p (Inwardly rectifying K+ channel protein) (Inwardly rectifying potassium channel 3, isoform A) (Q9VJ56)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003822}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003822}.
Interaction partners:
Sequence:
MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLRSSEKETVNASDYYPESPGFVRRRRSKAAGDHLETRSEQNFPYAHDWAGSTIELTPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKSHVELKLEGNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPKNDHLKLEYRK
Protein: G-protein coupled receptors family 1 profile domain-containing protein (A0A060YGE9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Early endosome {ECO:0000256|ARBA:ARBA00004412}.
Interaction partners:
- Chemokine
- Chemokine interleukin-8-like domain-containing protein
- Chemokine interleukin-8-like domain-containing protein
- Chemokine interleukin-8-like domain-containing protein
- Stromal cell-derived factor 1
- C-C motif chemokine
- Chemokine interleukin-8-like domain-containing protein
- C-C motif chemokine
- CXC chemokine d variant 1
- G-protein coupled receptors family 1 profile domain-containing protein
Sequence:
MPVYQGARCRTCFSQNEKMTTEFITDFTDYPTDNTDLDYDHWTQQCQKESNRHFRSWFMPTFYSLICFLGLVGNILVIGTYVYFNRLKTGTDVFLLSLSVADLLFVVSLPLWATNSMTEWVLGLFICKAMHTIYKVSFYSGMFLLASISVDRYFAISKAVSAHRHRSMAVFISKVTSVVIWVMALVFSVPEMSYTNISNKTCTPYTAGSDQVRVAIQVSQMVLGFVLPLLIMAFCYGAIVKTLCQARSFEKNKAIKVIFTLVAVFLLCQVPYNLVLLLTTLDAAKGGSKDCLYDNSLLYAADITQCLAFLRCCLNPFVYAFIGVKFRRDLLKLLKDLGCMSKERFFHTSQKFGHTYSFQGLLYWYYFLHLKTSKP
Protein: V-type proton ATPase subunit G (B2GUV5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- V-type proton ATPase subunit D
- V-type proton ATPase subunit B, brain isoform
- V-type proton ATPase subunit C 1
- V-type proton ATPase subunit F
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase 116 kDa subunit a 1
- V-type proton ATPase subunit E 1
- Vacuolar proton pump subunit B
- V-type proton ATPase subunit d 2
- V-type proton ATPase subunit H
Sequence:
MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSHGSCSSEVEKETQEKMTILQNYFEQNRDEVLDNLLAFVCDIRPEIHENYRING
Protein: Mitochondrial import inner membrane translocase subunit Tim9 (Q17754)
Organism: Caenorhabditis elegans
Function: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit Tim10
- Mitochondrial import inner membrane translocase subunit tim-13
- Mitochondrial import inner membrane translocase subunit tim-22
- Mitochondrial import inner membrane translocase subunit Tim8
- Mitochondrial import receptor subunit TOM7 homolog
- Uncharacterized protein F52C9.3
- Mitochondrial import receptor subunit TOM22 homolog
- Mitochondrial import inner membrane translocase subunit TIM14
- Large ribosomal subunit protein mL49
- Putative succinate dehydrogenase cytochrome b small subunit, mitochondrial
Sequence:
MTSEQNIQTFRDFLTQYNLVAEQCFNSCVNEFGSRTVSGKEESCANNCLDKFLKMTQRVSQRFQEHQLLNAQANGAAIKVENGGKINKIQ
Protein: Complement C8 gamma chain (A0A8I5YC83)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MWTSGLCFLWHWTVDSDLEQCTPPPPCPITYCHRTAMLSPGAVLFFTLILMASSLGQRTRKPYGSTSPISTIQAQANFNAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHIAPQGAAMAASTFRKLDGICWQVRQLYGITGVPGRFLLQAPRARGPVHVVVAETDYQSFAILYLEQARRLSVKLYTRTLPVSDSALNAFEERVRGANLTEDQIFFFPKYDNTYKREHRPLLHSFITLFKLRDNSEFQVTNSMTR
Protein: Small polypeptide DEVIL 4 (Small polypeptide ROTUNDIFOLIA like 17) (Small polypeptide ROT-FOUR-LIKE 17) (Q9SAF8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, including leaves shape, pedicule elongation, inflorescence organization and fruit maturation, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Small polypeptide DEVIL 2
- Small polypeptide DEVIL 20
- Small polypeptide DEVIL 8
- Small polypeptide DEVIL 11
- Large ribosomal subunit protein uL24y
- Small polypeptide DEVIL 16
- Dentin sialophosphoprotein-like protein
- CLAVATA3/ESR
- Small ribosomal subunit protein mS78
- Alpha/beta-Hydrolases superfamily protein
Sequence:
MKMGGSKRRVSSKGLGAVLKEQRAKLYIIRRCVVMLLCWHD
Protein: Chitin synthase 1 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase 1) (P08004)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation during adverse conditions.
Subcellular location: Cell membrane {ECO:0000305|PubMed:2523889}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Chitin synthase 3
- UDP-N-acetylglucosamine pyrophosphorylase
- Chitin synthase 2
- Chitin synthase regulator SKT5
- Chitin deacetylase 2
- Chitin deacetylase 1
- 1,3-beta-glucan synthase component FKS1
- Chitin synthase export chaperone
- Protein BNI4
- Chitin biosynthesis protein CHS5
Sequence:
MSDQNNRSRNEYHSNRKNEPSYELQNAHSGLFHSSNEELTNRNQRYTNQNASMGSFTPVQSLQFPEQSQQTNMLYNGDDGNNNTINDNERDIYGGFVNHHRQRPPPATAEYNDVFNTNSQQLPSEHQYNNVPSYPLPSINVIQTTPELIHNGSQTMATPIERPFFNENDYYYNNRNSRTSPSIASSSDGYADQEARPILEQPNNNMNSGNIPQYHDQPFGYNNGYHGLQAKDYYDDPEGGYIDQRGDDYQINSYLGRNGEMVDPYDYENSLRHMTPMERREYLHDDSRPVNDGKEELDSVKSGYSHRDLGEYDKDDFSRDDEYDDLNTIDKLQFQANGVPASSSVSSIGSKESDIIVSNDNLTANRALKRSGTEIRKFKLWNGNFVFDSPISKTLLDQYATTTENANTLPNEFKFMRYQAVTCEPNQLAEKNFTVRQLKYLTPRETELMLVVTMYNEDHILLGRTLKGIMDNVKYMVKKKNSSTWGPDAWKKIVVCIISDGRSKINERSLALLSSLGCYQDGFAKDEINEKKVAMHVYEHTTMINITNISESEVSLECNQGTVPIQLLFCLKEQNQKKINSHRWAFEGFAELLRPNIVTLLDAGTMPGKDSIYQLWREFRNPNVGGACGEIRTDLGKRFVKLLNPLVASQNFEYKMSNILDKTTESNFGFITVLPGAFSAYRFEAVRGQPLQKYFYGEIMENEGFHFFSSNMYLAEDRILCFEVVTKKNCNWILKYCRSSYASTDVPERVPEFILQRRRWLNGSFFASVYSFCHFYRVWSSGHNIGRKLLLTVEFFYLFFNTLISWFSLSSFFLVFRILTVSIALAYHSAFNVLSVIFLWLYGICTLSTFILSLGNKPKSTEKFYVLTCVIFAVMMIYMIFCSIFMSVKSFQNILKNDTISFEGLITTEAFRDIVISLGSTYCLYLISSIIYLQPWHMLTSFIQYILLSPSYINVLNIYAFCNVHDLSWGTKGAMANPLGKINTTEDGTFKMEVLVSSSEIQANYDKYLKVLNDFDPKSESRPTEPSYDEKKTGYYANVRSLVIIFWVITNFIIVAVVLETGGIADYIAMKSISTDDTLETAKKAEIPLMTSKASIYFNVILWLVALSALIRFIGCSIYMIVRFFKKVTFR
Protein: AT31918p (Q8T8R4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
LISKEALELHIKLIILTTACIFYITMCFMMIGCKYIANANPKRFAKIVHPSAVGFVLVGTVLFFSVEMFYMLPRIYDTDGLFFKIAWLMALFIVYNLLGNMLACHRNSSAVTSLPKDRQIPCPEEKHLWHFCDHCQMLVPVKYLP
Protein: Violet-sensitive opsin (Violet cone opsin) (Violet cone photoreceptor pigment) (P28684)
Organism: Gallus gallus (Chicken)
Function: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MSSDDDFYLFTNGSVPGPWDGPQYHIAPPWAFYLQTAFMGIVFAVGTPLNAVVLWVTVRYKRLRQPLNYILVNISASGFVSCVLSVFVVFVASARGYFVFGKRVCELEAFVGTHGGLVTGWSLAFLAFERYIVICKPFGNFRFSSRHALLVVVATWLIGVGVGLPPFFGWSRYMPEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIVPLSLIIFSYSQLLSALRAVAAQQQESATTQKAEREVSRMVVVMVGSFCLCYVPYAALAMYMVNNRDHGLDLRLVTIPAFFSKSACVYNPIIYCFMNKQFRACIMETVCGKPLTDDSDASTSAQRTEVSSVSSSQVGPT
Protein: lysozyme (EC 3.2.1.17) (D0R7H8)
Organism: Paenibacillus phage phiBP
Interaction partners:
Sequence:
MQQRNSRNAQGIDVSRYQGKIDWKAVKASGISFAFIKASQGKLYRDKTFIGNAQAARAVGVLVGAYHYLDDSAKTPEDARKEAANFVSAINSAGGIAAFDLPPVMDYESNKSGLSKAALTAVARTFLAEVERLTGVRPIVYTYPSFIGNFSGLSDYPLWIARYSATQVPPGASGWSRWDFWQYSDGSAGGTLPSGTRKVAGIAGPVDLNEFDGTADELRTRFRKKTSVPKEEPATVADGSFQINGENVGKALLFDGKTHVPLRVLADALGIPLRWDNAKKVAYLNNRKLQSVQLVEGVAYIQLRPIAESYGAEVSWDSKNRIASLKTKGEK
Protein: Clathrin light chain B (Lcb) (P09497)
Organism: Homo sapiens (Human)
Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular location: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Interaction partners:
- Clathrin heavy chain 2
- Clathrin heavy chain 1
- AP-2 complex subunit alpha-1
- Clathrin light chain A
- AP-2 complex subunit beta
- AP-2 complex subunit alpha-2
- Huntingtin-interacting protein 1
- Huntingtin-interacting protein 1-related protein
- AP-2 complex subunit sigma
- AP-2 complex subunit mu
Sequence:
MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
Protein: Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase) (A0A5F9ZHJ1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU368116}.
Interaction partners:
Sequence:
MIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
Protein: Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41) (Q8R574)
Organism: Mus musculus (Mouse)
Function: Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
Interaction partners:
- Phosphoribosyl pyrophosphate synthase-associated protein 1
- Ribose-phosphate pyrophosphokinase 2
- Ribose-phosphate pyrophosphokinase 1
- Ribose-phosphate pyrophosphokinase 1
- ribose-phosphate diphosphokinase
Sequence:
MFCVAPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTISKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHEIQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD
Protein: Cell wall protein PIR5 (Protein with internal repeats 5) (P46999)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the outer cell wall layer (By similarity). May be involved in meiosis and sporulation.
Subcellular location: Secreted, cell wall {ECO:0000250}. Note=Covalently attached to the cell wall. {ECO:0000250}.
Interaction partners:
- Probable pseudouridine-5'-phosphatase YKL033W-A
- Suppressor of lethality of KEX2 GAS1 double null mutant protein 1
- Oxidoreductase-like protein SRL4
- Serine/threonine-protein kinase PTK1/STK1
Sequence:
MHYKKAFLASLLSSIALTAYAPPEPWATLTPSSKMDGGTTEYRTSFGLAVIPFTVTESKVKRNVISQINDGQVQVTTQKLPHPVSQIGDGQIQVTTQKVPPVVSHIVSQIGDGQLQITTAKNVVTKSTIAVPSKTVTATATSTATAVSQIHDGQVQVTISSASSSSVLSKSKLEPTKKPNNEKVIKVQACKSSGTLAITLQGGVLIDSSGRIGSIVANRQFQFDGPPPQAGAIYAGGWSITKHGTLAIGDNDVFYQCLSGTFYNLYDQSIGGQCNPVHLQTVGLVDC
Protein: QKR54B (O44433)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTEKYEGNGDFSAFNDDDNDFGGKLANLVAPLADQVAPTMATSAHDHGHHGGDPGGNVQINEKANEYIRDCMAERNRMDRKFPIAEKLLEGEIEKVQTTGRIPSREQKYADIYREKPLRISQRVLVPIREHPNFNFVGKLLGPKGNSLRRLQEETLCKMTVLGRNSMRDRVKEEELRSSKDPKYAHLNSDLHVEISTIAPPAEAYARIAYAMAELRKYLIPDSNDIIRQEHVRELMDSTSLNDNDNAKSGYKKTSHMQGGNNVLGGGSINPIGGVKNTPHHSYRSSQPSSFSKNVLAPKQKVMSILEKARTAMDETYGRGYDDGLGYDPHQSYDSYSYGTHGHGPHGPPANILGGVGGISGGGGRGGHYESSDYEAGLWKTRILSAFTRLFCWRRRRCRSGHWRRFSIKCHRRLWSQFQSQSQPC
Protein: Quinone reductase (EC 1.6.5.2) (Chromate reductase) (CHRR) (EC 1.6.-.-) (NAD(P)H dehydrogenase (quinone)) (P0AGE6)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR (By similarity). Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen without producing the toxic Cr(5+) species and only producing a minimal amount of reactive oxygen species (ROS). Chromate reduction protects the cell against chromate toxicity, but is likely a secondary activity. Can also reduce potassium ferricyanide, 2,6-dichloroindophenol, V(5+), Mo(6+), methylene blue, cytochrome c and U(6+). During chromate reduction, is able to use both NAD or NADP equally well.
Interaction partners:
- Uncharacterized protein YieE
- Oxygen-insensitive NADPH nitroreductase
- FMN-dependent NADH:quinone oxidoreductase
- Uncharacterized NAD
- NADPH:quinone oxidoreductase MdaB
- Anti-sigma-E factor RseA
Sequence:
MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIADIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLPDQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQTGEVIDQGTLDHLTGQLTAFGEFIQRVKI
Protein: Interleukin-9 receptor (IL-9 receptor) (IL-9R) (CD antigen CD129) (Q01113)
Organism: Homo sapiens (Human)
Function: Plays an important role in the immune response against parasites by acting as a receptor of IL9.
Subcellular location: Cell membrane; Single-pass type I membrane protein. Secreted.
Interaction partners:
- Interleukin-9
- Cytokine receptor common subunit gamma
- Tyrosine-protein kinase JAK1
- Interleukin-4
- Interleukin-7
- Interleukin-2
- Interleukin-5
- Interleukin-13
- Thymic stromal lymphopoietin
- Protein sprouty homolog 3
Sequence:
MGLGRCIWEGWTLESEALRRDMGTWLLACICICTCVCLGVSVTGEGQGPRSRTFTCLTNNILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPPEAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLTCGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPGNTQSSGPIPALACGLSCDHQGLETQQGVAWVLAGHCQRPGLHEDLQGMLLPSVLSKARSWTF
Protein: AAA-ATPase At2g18190 (EC 3.6.1.-) (F4IQG2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MFPSISNISLSPSSLFTAYASLTGFLMLFRSLFNDEVPERLRSYITDLLNRFFTPKSKNLTMVIDEIIGFKRNQVFDAAEVYLRNKIGPETARLRVGKLPKQKHFTIYIEKGEEILDTFENSELRWTYVESENEASQKEKRYYELTFEKKLRDKVMNSYLSHVVAESEETKRDLRAVKLYSRDVRASKDDDGMAGAGWGCINLEHPSTFETLAMDPGAKKKIIDDMERFLKRREFYKRVGKAWKRGYLLYGPPGTGKSSLIAAMANYLKFDVFDLELSSIYENAQLKSILLSTTNRSILVIEDIDCSSAEVVDREADEYQEYEEGYYGRVTLSGLLNFVDGLWSSFGDERIIVFTTNHKERLDPALLRPGRMDMHINMSYCTGLGFRTLVSNYLGLGGLNHPLCEEIEALIDSTEVTPAELAEELMQEDDTDVVLRGVVSFVENRKVEISKTKELEGSTCRKLDGDDKHNVSSTNDLKKTKKKKKGGKGKAKGN