wanglab/gogpt-training-data huggingface dataset:
Protein: Protein disulfide-isomerase (EC 5.3.4.1) (Q3YMU0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
- Calreticulin
- Endoplasmic reticulum chaperone BiP
- Calnexin 99A, isoform A
- Heat shock protein 83
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Ero1-like protein
- T-complex protein 1 subunit alpha
- DSec61alpha
- Protein disulfide-isomerase A6 homolog
- Eukaryotic translation elongation factor 2
Sequence:
MMWRLAGVLLLGFIAISSGAEQDVLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIAKYMRAQVGPASKTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQGETDKIVLIRAPHLSNKFESSSIKFEGSSESDLSTFVKENFHGLVGHRTQDSVKDFQNPLITAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQHELNEYGYDFVGDKPVVLARDEKNLKYALKDEFSVENLQDFVEKLLANELEPYIKSEPIPESNDAPVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAEKLQDEDVAIVKMDATANDVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVDDFLKYIAKEATTELKGFDRSGKPKKTEL
Protein: DnaJ homolog subfamily C member 14 (H0YHG0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XPALQRCLTLLRDSRPWQRLVRIVQWGWLELPWVKQNINRQGNAPVASGRYCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNAEKRKEYEMKRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRIPGTRGRQRATPDAPPADLQDFLSRIFQVPPGQMPNGNFFAAPQPAPGAAAASKPNSTVPKGEAKPKRRKKLAELKQECLARGLETKGIKQDLIHRLQAYLEEHAEEEANEEDVLGDETEEEETKPIELPVKEEEPPEKTVDVAAEKKVVKITSEIPQTERMQKRAERFNVPVSLESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAERFGIA
Protein: Gamma-tubulin complex component (Q9VXU8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000256|RuleBase:RU363050}.
Interaction partners:
- Gamma-tubulin complex component 4 homolog
- Gamma-tubulin complex component 3
- Gamma-tubulin complex component 2 homolog
- Grip163
- Tubulin gamma-1 chain
- Grip71
- Tubulin gamma-2 chain
- Gamma-tubulin complex component
- Testis-specific gamma-tubulin ring protein 91
- GEO02508p1
Sequence:
MAPPAQKGNLRKRSGKTSTAVNSAINENVRKLVRSLSEPGTSQKKLRQMEDTALKIIANQRRTWAPTTTDMEVKRNLDDLAERFRAEGMASFGESIKDLAIRYLAMDENQQQFNPNPGWQMLELLFRIADRPVQKIRLNREFMEQRRLSIINSMEEAERQAQIEEQAKLEAAKNTSETEVDWAALLSEDFLDPPEDDSSDSLSDWSEESDCDSTTTLKPDENIGVSRSLLEMARVYEQAMMAVVPTGSVNKTYMPPEQSVIRSYDFRIMKPTVLSLNNLKGSHLRRSKLLQLPPPQPPRPFTQYWQSGNTDTLFRKIHSHWWCQDVHLNALPSSAKPLDNFAVSYVQFLNHNARGLLALPVPKTITEPCLLREILFMFVRPASCCFFEFDKATRRITVRDNVSICTVTASTMQNFLLFDVVPALEDMMELRHIIDTHTLHFHGVKTTYTVEFFAYGLRDLVQPICQLLIAYEDRVNKDPAKNTLIRFTIEFREHFSQLRLLRELAEDVILDKGPAHIRSAYLLSRLYKHTLLQVPHQKLATALLFISLKRYCIIIDGWWRRAALEDHLREFIVEFCYEEDANTRSHVRKRNMGMEDDLLLVEIFNKLQSCPLYQLLLEHALESGETQDLLCSVNTLSEMLTSNNEIQLPSLHDELFTQFFAQLKVYCGADNTDYEDEPEPDKDYEDLTVCNRQGIRNHELFAIFTQPLVEQRLERQRERLKSNPVLMANILKRLERSTCLQLKSELPEALREILRRRQWLANEYAIRAYCKETQVAEKMRFLRHTMLLEKYYLFVPYYNALFVRMEKNNSWALGSVLTSKLCAVLLPHYPQLAHYLHVKLISQINSNSIKVYEALEAIELDFERPMAMHQWYILTPAHMQDYNSVWRLMLKVKWAVWKLENMQFLRRARFNPCAPLDLIGLTIRRLEIVRFWLIFLINNLHAHIMEAVSRQFELRIGECKNVRELRIMHDEHLAWLKTHCMLTDEFKAFRVALDQIFHLVYVLDMEWTTCASCMHDHDALCLDVTISDDGIDDSETQRRSLEYLALNQVAEIELTYIRCHQMLADILNTLVHQNDHGFLSALEETINSSVPH
Protein: F1O19.7 protein (Transmembrane protein) (Q9FZH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MALGDESEVFESENCHGDETERNMKVLFGGFKRLCADKVQHEEKLESMDSVLRQVVATLERMEIREGKRVEQGEHSCQSPRHSFSSSMPQRGAGESPILLDNRSSLIRRIEMPVFDGSGVYEWFSKVERFFRVGRYQDSDKLDLVALSLEGVALKWFLREMSTLEFRDWNSFEQRLLARFDPVKIHSSPEVLMPTTLIHVVAHETESRCTEELIEEDESSVRKKSNPEIVLITQKKSFPRFQNVATIVVGEFQEGTWFFDDKSKDNEANNSSDSKLKFGAYKVLDKILIRSHNLKQRRKLSLSPKNWMFKFKNRNLQQNRSKMDPCQAIEFSNIHYMYLCFSANVGLVRKNKSFQSLRLKKQAHMSRDLKKLESISSEELQPALPIVETLGDEDMVALQSDLRRLGEANFATIDSAQLLRLDDATLMNSALKRKCSKSWHFIYKHYKVRMQNLHTGIYKTQRPWHCLVHEANNTDSHLWHRWKTKVETLQEISEFLSWGLVHSHSSEVISFLGFSHGPLVTVNGASSDKVIDAAATSIFSEAIGLQQYEKVMILCMRLFTCMTLTGMMIVLFSSGCAICVFESCHRLTHKLKKDQSMSLHNIKKRKFLKAWKFKYKQKVDKRDMAAYQNSEATQIIQKLVVSFFLLLSLRTSLSKWGEY
Protein: Conserved protein similar to jag protein (O53598)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- RNA-binding protein KhpA
- Membrane protein insertase YidC
- Ribonuclease P protein component
- Putative membrane protein insertion efficiency factor
- Ribosomal RNA small subunit methyltransferase G
- Probable helicase
- ATP-dependent RNA helicase DeaD
- Ribonuclease J
- Probable chromosome-partitioning protein ParB
- Probable cold shock-like protein B CspB
Sequence:
MADADTTDFDVDAEAPGGGVREDTATDADEADDQEERLVAEGEIAGDYLEELLDVLDFDGDIDLDVEGNRAVVSIDGSDDLNKLVGRGGEVLDALQELTRLAVHQKTGVRSRLMLDIARWRRRRREELAALADEVARRVAETGDREELVPMTPFERKIVHDAVAAVPGVHSESEGVEPERRVVVLRD
Protein: Transposon Ty2-OR2 Gag-Pol polyprotein (TY2A-TY2B) (Transposon Ty2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA); Ty2 protease (PR) (EC 3.4.23.-); Integrase (IN); Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4)] (Q12501)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).
Subcellular location: Cytoplasm. Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MESQQLHQNPHCPHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQEETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTKVRNNVLPPHPHTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYSDILTVLCKSVSKMQTNNQELKDWIALANLEYNGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTRTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELTNQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQNNQTKLDQFDYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSLNPLQLDKEPVQKVRAPKEVDADISEYNILPSTIRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSDSTTPIISIETKAACDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
Protein: Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 4 (AthCYSTM4) (Q9SKY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in resistance to abiotic stress.
Subcellular location: Cell membrane {ECO:0000269|PubMed:29272523}; Single-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:29272523}.
Interaction partners:
- Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM3
- CLAVATA3/ESR
- Cysteine-rich and transmembrane domain-containing protein PCC1
- Splicing factor U2af large subunit A
- Multiple C2 domain and transmembrane region protein 16
- Cell cycle regulated microtubule associated protein
Sequence:
MSQYSQNQSSGAYPTPPVSTGPYMTPPPLGYPTSDISHATVAPVETKSKGDGFLKGCLAAMCCCCVLDACF
Protein: Kinesin-like protein (A0A286Y967)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MIRQAKGKTPRRPPPKKPSNNQKDPVGVYCRVRPLGAEDEECCIEVISNTTIQLHAPDGLKANRNGEFKETQYSFKKVFGIKTTQRELFEDVAKPLAQDLIHGKNGLLFTYGVTGSGKTHTMTGSPGQGGLLPRSLDMIFNSIGPYQAKRYVFKPDDKNGMEVQNQVDALLDRQKRDSQTSVPKTPNTRRVDPEFADMISPEEACKAEGVDEDSSYSVFVSYIEIYNNYIYDLLEETPFDPIKPKWNGAGTPVRNITEFIPPQSKILREDQNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTQLNRESSRSHSVFIVKLAQAPLDADGDNVLQDKNQVNVSQLCLVDLAGSERTSRTRAEGNRLREAGNINQSLMTLRTCIEVLRENQMCGTNKMVPYRDSKVTHLFKNYFDGEGKVRMVVCVNPKADDYEETLLVMRFAEMTQEVEVARPVDRPICGFAAGRRQRNQAFKEELTRRLEERGGPVDGDCPTVLNQLLQAFPPLPPCEISGPNDDVTLPRLIEALEKRHKIRQMMIEEYNKTATMLKSVLQEQDGNILSKENVIQEQRGKLGEKDKMLQNQKNEIDRLEKKSKMLEYKIDILQKTTNIYEEDKRSLQNELESREQRLQREMSEKRRIEARMQGMVSDTKLKWEKECERRVNAKQLEMQNKLWVKDEKLKQLKAIVTEGKTENRQPQRPSREKDKVPPKRSASPSPAPTGPPVRPLHRRSHSAGGERWVDHKPTTNVDLDTVMQPNIPNAIKVNAPNEKALSKCDKYVLTHQEVASDGEIQTKLIKGEVFKTRGGGQSVQFTDIETLKQETPVAASRKRRSSESGPDSEPMEGNWTDVETRCSVAVEMRAGSNLGPGYQHHGYTKRRKP
Protein: Probable inactive receptor kinase At1g48480 (Q9LP77)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein RALF-like 1
- BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1
- Protein BRASSINOSTEROID INSENSITIVE 1
- GPI-anchored protein LLG1
- Rapid alkalinization factor 23
- GPI-anchored protein LORELEI
Sequence:
MRVFFFPNSSMAILSVFLSLLLLSLPLPSTQDLNADRTALLSLRSAVGGRTFRWNIKQTSPCNWAGVKCESNRVTALRLPGVALSGDIPEGIFGNLTQLRTLSLRLNALSGSLPKDLSTSSNLRHLYLQGNRFSGEIPEVLFSLSHLVRLNLASNSFTGEISSGFTNLTKLKTLFLENNQLSGSIPDLDLPLVQFNVSNNSLNGSIPKNLQRFESDSFLQTSLCGKPLKLCPDEETVPSQPTSGGNRTPPSVEGSEEKKKKNKLSGGAIAGIVIGCVVGFALIVLILMVLCRKKSNKRSRAVDISTIKQQEPEIPGDKEAVDNGNVYSVSAAAAAAMTGNGKASEGNGPATKKLVFFGNATKVFDLEDLLRASAEVLGKGTFGTAYKAVLDAVTVVAVKRLKDVMMADKEFKEKIELVGAMDHENLVPLRAYYFSRDEKLLVYDFMPMGSLSALLHGNRGAGRSPLNWDVRSRIAIGAARGLDYLHSQGTSTSHGNIKSSNILLTKSHDAKVSDFGLAQLVGSSATNPNRATGYRAPEVTDPKRVSQKGDVYSFGVVLLELITGKAPSNSVMNEEGVDLPRWVKSVARDEWRREVFDSELLSLATDEEEMMAEMVQLGLECTSQHPDQRPEMSEVVRKMENLRPYSGSDQVNEAD
Protein: Cytokine receptor (Protein domeless) (Q9VWE0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Critical for epithelial morphogenesis during oogenesis; border cell migration. Required in the germarium for the polarization of follicle cells during encapsulation of germline cells. Required for embryonic segmentation and trachea specification. Essential receptor molecule for upd and JAK/STAT signaling during oogenesis.
Subcellular location: Apicolateral cell membrane {ECO:0000269|PubMed:12403714}; Single-pass type I membrane protein {ECO:0000269|PubMed:12403714}. Note=Apicolateral membranes in follical cells.
Interaction partners:
- Outstretched
- FI03911p
- Tyrosine-protein kinase hopscotch
- Unpaired 2
- Signal transducer and transcription activator
- Suppressor of cytokine signaling at 36E, isoform D
- Protein immune deficiency
- Suppressor of variegation 2-10, isoform I
- Tyrosine-protein phosphatase non-receptor type 61F
- Epidermal growth factor receptor
Sequence:
MVAQEQLVLLLMLLAGCRGGANAILDPGWVIPSKVEQLIGGDFNLSCTLNEDYFNGKSAEDCPVEKLYFTGGGRVYRDSKHIRILNNTTILFSDTNAVEQENDYHCMCDEYVINKSKVYVGTRPLLVRDFNCLDYDFQFMVCNFTQPPNTVITKYNISYNTNNDWRYSNTLDCNFDSAPVVTCNLTDDNYKRFSETFYFRLSISNALGHETQPITINHFERLVPARPGQNLTLLNRTESSVCLSWEMPRRSNYNRGLVWQVRVTPQNFEPITRPSWRNHTLTIKDTLCLTELPFAGYNYTLRVRVRANQNNTLWSEPMIYAFATAPAPPRRPPRVTYGSFYVYSSEKAMRFYWEPLEEHELNGPDFRYSISEYRINGTAVDPGLIKVESNSAMIDHWSMSAVHHFLIRSSNSQGLSVNATPMTIGPISNRDFKVREPRNIRSVYHPTNKSYTLSWDPPSDQRELQNYTVFWCVPKPGLQSECEGSIRFAEVASGLHHFTTSPDQLLTLHMAVSANYQSHNTGLHWAICSSDKKDDLAKMEPSIDVATSTSLTVSWSERVCAVILAGYNLTYCQRSAGRPDNCTTVTIDRYTNKHVIQNLVPYTDYSVKMLMYSDSRVSKYSDELVNRTGEAAPSQPRELQLIRVTSDSVELAWKPPLLANGVVRAYEGTFRSLHDNVTDTFRVSASADELVNNEKPITYRLGNLTAFTKYEISVRARTVYPSEPSNVILFSTAIGVPSPPQLYVINNPDQSSRLDWEPPRTPAGRIDFYEISLRDNNASCLTSTILPGRNLSYVMATPRCTSHNPFQLAVRAINVEQHPQLNGADAAEGAVLLMSTNGKGCEARTDALGEEERLQFEAYAANMTAYRLYRSDWGIYGFICTPDTHSVKAMYQTIEVTVAILVLGVIFYLVYKKYRKMSDIGLVLPQGIMETMKKPIDMGGLGLGLGPDSSVSGGIVCTRVDDSPPYTPQDLPHDFSSCGSESSKLLLRTASSSGGGGCVDRDGYDDNHETGPISAVGPPTSYLAMRHGLLVQNDRERERERDREQEREREQQQQQRESEMDREQSCTNGYIKPTQMKSWGGNGPSDNDHTFSVPSTAMTAPMSQPLSQIPLSGYVPVPIPQSRFNPAPVQPFGSPAVPSAATAAAASTFFPPAHLLNMDNYVQASDLHKLKPLVAAPLSQTGGPAFAGSSPATSPPLQLPPVHAASPAAATPKMADIGYTTMEQLQLTGLIKPPLAATVGSPTHAAGGAPGGGNQHSRLQPQINGYVTPQDLNAMAHNRHVL
Protein: Fibroblast growth factor receptor (EC 2.7.10.1) (F1LSG7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}. Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00004541}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
- Fibroblast growth factor
- Fibroblast growth factor 10
- Fibroblast growth factor 7
- Fibroblast growth factor
- Fibroblast growth factor 20
- Fibroblast growth factor 1
- Fibroblast growth factor 9
- Fibroblast growth factor 16
- Fibroblast growth factor 2
- Fibroblast growth factor 17
Sequence:
MGLPSTWRYGTGPGIGTVTMVSWGRFICLVLVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEACVVAPGESLELRCMLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACAAARTVDSETLYFMVNVTDAISSGDDEDDTDSSEDFVSENRSNQRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEMDAGEYICKVSNYIGQANQSAWLTVLPKQQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYDPCLPQYPHINGSVKT
Protein: UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2-epimerase) (Q6LZC4)
Organism: Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL)
Function: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- UDP-N-acetyl-D-mannosamine dehydrogenase
- UDP-N-acetylglucosamine 2-epimerase homolog
- UDP-N-acetyl-D-mannosamine dehydrogenase
- Bifunctional protein GlmU
- Na+/H+ exchanger
- Glutamine--fructose-6-phosphate aminotransferase
- Glycosyl transferase, family 2
- Polysaccharide biosynthesis protein
- DegT/DnrJ/EryC1/StrS aminotransferase
Sequence:
MYKIGIILGTRPEIIKMSPVIRELTTKKFFLIHTNQHYSENMDKIFFEELNLKKPDYNLNIGSGSHGDQTGRMLMEIEKVLLKEKPDFVLVQGDTNTVLAGALAASKLGIKIGHIEAGLRSFDRKMPEETNRVLTDHISEFLFAPTKTAANNILKEGISDEKIHIVGNTIVDATIQNLKIAEKNEKVCKFISKITKNEKYFLLTLHRAENTDNFEILSKLVTSINNISKKYEKNIIFPIHPRTHKKLNEFGLINKLENNHLIKIIEPVGYLEFLGLEKNAELIITDSGGLQEEACILNVPCVTLRENTERPETLDVNSNILAGSDPENILNCVEKMLKSNRHWNNPFGDGNSGKIIVNIVFGEKKP
Protein: Neuroligin-like protein glit-1 (Gliotactin homolog) (Inactive esterase glit-1) (Q20826)
Organism: Caenorhabditis elegans
Function: Probable neuronal cell surface protein thought to be involved in cell-cell-interactions (Probable). Confers protection against oxidative stress. Plays a role in protecting dopaminergic neurons against oxidative stress-induced neurodegeneration.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Neurexin-3-beta
- Neuroligin-1
- J domain-containing protein
- Large ribosomal subunit protein uL23A
- Tetraspanin-17
- Transthyretin-like protein 33
Sequence:
MFTGTIFNSLFTLPLVISQFVPPPTRPVDLWDPFKTTTTPFPHGGVNQGLNRDEVVVRLPLGDIVGKEVHLHNLPWTIHKDPTEELPKDGTHFDPNPLKPKNNITVFTFLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQDVEKSPSPFVDHPYPFMVDEDCLYLNIFSPDISKNAQTTYPVIVFFHGGNFQTGSANEWPAHGLASRGMVVVTVNYRLGAFGFMSMGDSETGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHLFRSAATMSGAEVSYHSYIGKTALAFNNTMKLGRYAGCTQAVAQHRWDCILTRSTGDIIDATRNIPIEYNRYLFMPTVDGKYLPGNPLWTLVNAPSGETSIMSPVPMLIGMNAQDGSEVVLEDRRLGEFSQFNDVDHEYLKSYSLEYCYRHNYSMNREATADAILSKYTFWPDRAAAWAIKENFIQFATDAYYTAPMQLSSHLHSSSGSRVFQYVNNYNFSRQHPNLLFIPDWMGVCRDCDLYLMFGYPFLPDELRPIGLRGINFTDTDRNASRTFSNIIRRFSYHQNPNFQFDGSWAAYEPRRHWYINFNYTHEEDWKIPGTLARDYRYQDVAFWNEYIPALVNYMTTTFSPENVAYRREIMVFKWITGVNVIIIALLIVLAGAFGYMVWGNKEDEEAAYKAENHQLVEYRDTGHSVSDATISSRTRSPRSRITNL
Protein: Methyltetrahydroprotoberberine 14-monooxygenase (EC 1.14.14.97) ((S)-cis-N-methylstylopine 14-hydroxylase) ((S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase) (Cytochrome P450 82N4) (Methyltetrahydroprotoberberine 14-hydroxylase) (N-methylstylopine hydroxylase) (PsMSH) (L7X3S1)
Organism: Papaver somniferum (Opium poppy)
Function: Catalyzes the conversion of N-methylated protoberberine alkaloids N-methylstylopine and N-methylcanadine into protopine and allocryptopine, respectively, in the biosynthesis of isoquinoline alkaloid sanguinarine.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MRTESIKTNRPMDLLLQYLQPISVALVVIALVWNYGRRNPTKKLAPEASGGRPIMGHLHLFNDGELTHRKLGAMADTYGPVFNIRFGSHKTLVVSDWEIVKECFTTNDKLFSNRPGTLGIKLMFYDADSVGYAPYGAYWRDLRKISTLKLLSNHRIDTIKHLRSSEVESCFESLYSQWGNGEKSGEFAPVRMDSWLGDLTFNVVARIVAGKKNFSANGDVGAQRYKAAMDEAMRLMRFFAFSDVIPSLSWLDNLRGLVREMKKCASEIDSIMATWVEEHRVKRNSGGNSQLEHDFIDVCLDIMEHSSLPGDDPDLVVKSTCLDMILGGSDTTTVTLTWAMSLLLNHPQVLQKAKEELETQVGKNRQVDDSDIPNLPFIQAIIKETMRLYPAGPLIERRTMEDCEVAGYQVPAGTRLLVNVWKMQRDGNVYKGDPLEFRPDRFLTSNADVDLKGQHYELIPFGAGRRICPGVSFAVQLMHLVLARLLHEFEITTVEPETKVDMAESGGLLCYKIMPLEVLIKPRLEI
Protein: E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Praja-1) (O55176)
Organism: Mus musculus (Mouse)
Function: Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome. May be involved in protein sorting.
Interaction partners:
- Melanoma-associated antigen D1
Sequence:
MSHQERIASQRRTTAEVPMHRSTANQSKRSRSPFASTRRRWDDSESSGASLAVESEDYSRYPPREYRASGSRRGLAYGHIDTVVARDSEEEGAGPVDRLPVRGKAGKFKDDPEKGARSSRFTSVNHDAKEECGKVESPPAARCSARRAELSKQNGSSASQISSAEGRAAAKGNNSLERERQNLPARPSRAPVSICGGGENTPKSAEEPVVRPKVRNVATPNCMKPKVFFDTDDDDDVPHSTSRWRDAADAEEAHAEGLARRGRGEAASSSEPRYAEDQDARSEQAKADKVPRRRRTMADPDFWAYTDDYYRYYEEDSDSDKEWMAALRRKYRSREQPQSSSGESWELLPGKEELERQQAGAGSLASAGSNGSGYPEEVQDPSLQEEEQASLEEGEIPWLRYNENESSSEGDNESTHELIQPGMFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL
Protein: hydrogenase expression/formation protein HypD (Q5JII1)
Organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Interaction partners:
- Hydrogenase expression/formation protein HypC
- Hydrogenase expression/formation protein HypE
- Carbamoyltransferase
- Hydrogenase expression/formation protein HypE
- Cytosolic NiFe-hydrogenase, alpha subunit
- Hydrogenase maturation factor HypA
- Hydrogenase expression/formation protein HypE
Sequence:
MEEPFEAYRSREVAMKLVEKIREEAKTLDGEIRIMHVCGTHEDTVTRHGIRSLLPENVKVVSGPGCPVCITPVEDIVAMQLIMRKAREEGEEIILTTFGDMYKIPTPMGSFADLKSEGFDVRIVYGIFDTYRIAKENPDKTVVHFSPGFETTTAPAAGMLNVAAQEELENFKIYSVHRLTPPAVEVLLKQGTVFQGLIAPGHVSTIIGVKGWEYLTEKYGIPQVVAGFEPNDVLMAILMLIRMYKEGEARIINEYERAVKYEGNVVAQKMIDKFFEVVDAKWRALGVFPKSGLELRKEWKDFEIRSFYKVEVPKNLPDLEKGCRCGAVLRGLALPTDCPLFGKTCTPRHPVGPCMVSYEGTCQIFYKYGVLF
Protein: Small nuclear ribonucleoprotein SmD1 (D6XKM9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- G10 protein
- Spliceosome-associated protein, putative
- Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats domain-containing protein
- U5 small nuclear ribonucleoprotein component, putative
- Sm protein B
- Sm protein G
- Sm protein F
- Small nuclear ribonucleoprotein E
- U1 small nuclear ribonucleoprotein, putative
- U2 small nuclear ribonucleoprotein B, putative
Sequence:
MPAAESSTLIGFLQQLRGTQVEIEMMNSTIVTGEITFVEANMNTYMRHVKITAKGKNPEMAETYMVCGSKIRYVILPEAMNTDDVLVKAAAAKARPGSKRTERSNE
Protein: Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) (P52873)
Organism: Rattus norvegicus (Rat)
Function: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:P11498}.
Interaction partners:
- Citrate synthase, mitochondrial
- Malate dehydrogenase, mitochondrial
- NADP-dependent malic enzyme
- Glutamate dehydrogenase 1, mitochondrial
- Phosphoenolpyruvate carboxykinase, cytosolic
- Malic enzyme
- L-lactate dehydrogenase A chain
- Malate dehydrogenase, cytoplasmic
- Malic enzyme
- ATP-citrate synthase
Sequence:
MLKFQTVRGGLRLLGVRRSSTAPVASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTNSPINSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGIVDTQFIDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKVSPSPVDPIVPVVPIGPPPAGFRDILLREGPEGFARAVRNHQGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFNNLFSIENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVFKFCEVAKENGMDVFRIFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSLEYYMGLAEELVRAGTHILCIKDMAGLLKPAACTMLVSSLRDRFPDLPLHIHTHDTSGSGVAAMLACAQAGADVVDVAVDSMSGMTSQPSMGALVACTKGTPLDTEVPLERVFDYSEYWEGARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQMLGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGIPHGGFPEPFRSKVLKDLPRIEGRPGASLPPLNLKELEKDLIDRHGEEVTPEDVLSAAMYPDVFAQFKDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFELNGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDVKVAAGAKVVKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE
Protein: B9 domain-containing protein 1 (MKS1-related protein 1) (Q9VF59)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Required for ciliary structure and function.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:22508513, ECO:0000269|PubMed:25447994, ECO:0000269|PubMed:27577095, ECO:0000269|PubMed:27646273, ECO:0000269|PubMed:30013109}. Note=Localizes at the transition zone (TZ), a region between the basal body and the ciliary axoneme in the olfactory, auditory and speromatocyte system (PubMed:27646273, PubMed:30013109). In spermatocytes, localizes in the transition zone and the migrating base of the spermatid ciliary cap (PubMed:25447994, PubMed:27577095). Co-localizes with the tectonic-like complex (PubMed:27646273). {ECO:0000269|PubMed:25447994, ECO:0000269|PubMed:27577095, ECO:0000269|PubMed:27646273, ECO:0000269|PubMed:30013109}.
Interaction partners:
- B9 domain-containing protein 2
- Coiled-coil and C2 domain-containing protein 2A
- Tectonic
- Tectonic-like complex member Mks1
- GEO07735p1
- Centrosomal protein Cep290
- Transmembrane protein 231
- Uncharacterized protein
- Diphthine methyltransferase
- Uncharacterized protein, isoform C
Sequence:
MSASEGISLPGNEETTPPHEKHKQKAKKAKKKSRSAKESVPNAMDAKATASYFSLSIVGQIVSATFPLGPDKEFVFLRYEMVAGPDWQLSSGPQHGLTQLATNRRGHFNEPIVFNMPIEVTYKSTSPYGWPQILVTVFGRSGLGRETLLGYAHIHLPVFGSRRPADQTEQLQAPILMPKCPNMMADITSWLLRREPELKDPKVLLDNLKCKGLSMESYGSLQFQLSSVMRGARKLGYHWHS