wanglab/gogpt-training-data huggingface dataset:
Protein: NADPH-dependent methylglyoxal reductase GRE2 (EC 1.1.1.283) (3-methylbutanal reductase) (EC 1.1.1.265) (Genes de respuesta a estres protein 2) (Isovaleraldehyde reductase) (Q12068)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG, 2-oxopropanal) to (S)-lactaldehyde as an alternative to detoxification of MG by glyoxalase I GLO1. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation. Also catalyzes the reduction of 3-methylbutanal to 3-methylbutanol. Acts as a suppressor of 3-methylbutanol-induced filamentation by modulating the levels of 3-methylbutanal, the signal to which cells respond by filamentation. Also involved in ergosterol metabolism.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Glutathione-independent glyoxalase HSP31
- Glyoxalase I
- Probable glutathione-independent glyoxalase HSP32
- Probable glutathione-independent glyoxalase SNO4
- Probable glutathione-independent glyoxalase HSP33
- Tryptophan synthase
- Small ribosomal subunit protein uS19
- Uncharacterized membrane protein YML131W
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
Sequence:
MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI
Protein: Signal transducer and activator of transcription b (Zinc finger protein STAT-B) (Q20977)
Organism: Caenorhabditis elegans
Function: Carries out a dual function: signal transduction and activation of transcription (By similarity). By regulating the up-regulation in the epidermis of antimicrobial peptides nlp-29, plays a role in resistance to fungal infection and in the response to physical wounding and phorbol ester PMA treatment.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P51692}. Nucleus {ECO:0000269|PubMed:21575913}. Vesicle {ECO:0000269|PubMed:21575913}. Note=Translocated into the nucleus in response to phosphorylation (By similarity). Localized to vesicles, which may be a type of endosome (PubMed:21575913). {ECO:0000250|UniProtKB:P51692, ECO:0000269|PubMed:21575913}.
Interaction partners:
- Sodium-dependent transporter snf-12
- Transmembrane matrix receptor MUP-4
- Neuropeptide-like protein 29
- Guanine nucleotide-binding protein alpha-12 subunit
- G-protein coupled receptors family 1 profile domain-containing protein
- Protein nipi-3
- Protein kinase C-like 1
- Transcription factor elt-3
Sequence:
MSSVVSDQMDIESSSAFSPAEPVVDGAFVSKHNLSAEAYQGFKECADSLLSGKIAQNEQLPFIQRTLQICENVILNFEDEKQHLMSDVLLVWAMKQQKLSIATLHTQQLHYKELDLINLQFEYFGELLQQTLSGLDYLKQYYPNVGFEEVHSKVRNLTHYFLYYSIIVSRQPPSVIVKCGEAENHRRSRFWFNTEIRILGGSAFGIDTNNENSNVNCYLITDETAKQLLNNAYLDIFESEEFCIEPNTSTFQKKDARGIKAKFDDMKVAKKVALRRDSVATKRYCLCYNIQLQTNCGIELVGKKVSLPFAVLVGPKADVEAKLFLERSFADLVRHPLSDIPTHVSCAEMADALEMKFQAIIETPQKNTDGPSVVQPRKFNMQTKQHLVMRMKPNNQGFLPLDNFMKLPVAEEFQHKKSASAEGDWKLVPFYDWFFKLAEITNKYLYSMWYDGLVYGFCSKEDAENILRCIPRSVLLVRFSDIEYGKIKISVKNRNGEIRHHWYEHADLNARSLNSELLSNHKFSDVDLIYPDIDLEVALGGRNKPRIRLPRNLAPDEIYFDNQGAAT
Protein: Mitochondrial substrate carrier family protein (Putative mitochondrial carrier protein) (O64731)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
- Asparagine--tRNA ligase, cytoplasmic 3
- Asparagine--tRNA ligase, chloroplastic/mitochondrial
- Phosphatidylinositol-3-phosphatase myotubularin-1
Sequence:
MATEATTKFPESDLRPIPQPPDFHPAIIVPAQNTTLKFWQLMVAGSIAGSVEHMAMFPVDTVKTHMQALRSCPIKPIGIRQAFRSIIKTDGPSALYRGIWAMGLGAGPAHAVYFSFYEVSKKFLSGGNPNNSAAHAISGVFATISSDAVFTPMDMVKQRLQIGNGTYKGVWDCIKRVTREEGFGAFYASYRTTVLMNAPFTAVHFTTYEAVKRGLREMLPEHAVGAEDEEGWLIYATAGAAAGGLAAAVTTPLDVVKTQLQCQGVCGCDRFKSSSISDVFRTIVKKDGYRGLARGWLPRMLFHAPAAAICWSTYETVKSFFQDLNGEANAA
Protein: AT3g14620/MIE1_12 (Cytochrome P450) (Q9LUD2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Probable serine/threonine protein kinase IRE4
Sequence:
MSDTKISAVAVAAAVVVVTTVTVWIWKGLNVAWLRPKKNEAYLKRQGLSGTPFTFLVGDIKREASMVEQEKSRPINLTDDYTHRVMPLIQQTVKDHGKTSYMWMGPIASVIVTKPEHIKDVLNRVYDFPKPPVHPIVELFATGVALYEGEKWSKHRKIINPSFHLEKLKIMIPAFYESCSEMISKWEKLVTEQGSSNEIDVWPYLGDLTSDVISRTAFGSSYEEGKRIFELQEEQGRRVLKALELAFIPGMRFLPTKNNLRMRQINKEVKSRLREIIMKRQRGMDTGEAPKNDLLGILLESNSGDHGMSIEDVVEECRLFHFAGQETTAVLLVWTMIMLSHHQKWQDQAREEILKVIGKNNKPNFDALSRLKTMSMILNEVLRLYPPGILLGRTVEKETKLGEDMTLPGGAQVVIPVLMVHRDPELWGEDVHEFNPERFADGISKATKNQVSFLPFGWGPRFCPGQNFALMEAKMALVLILQRFSFELSPSYTHAPHTVLTLHPQFGAPLIFHML
Protein: H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1) (Q9NY12)
Organism: Homo sapiens (Human)
Function: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Subcellular location: Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Interaction partners:
- H/ACA ribonucleoprotein complex subunit 2
- H/ACA ribonucleoprotein complex subunit 3
- H/ACA ribonucleoprotein complex subunit DKC1
- Telomerase Cajal body protein 1
- Protein SHQ1 homolog
- rRNA 2'-O-methyltransferase fibrillarin
- Nucleolar protein 58
- Nucleolar protein 56
- Telomerase reverse transcriptase
- RNA 2'-O-methyltransferase FBLL1
Sequence:
MSFRGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRGH
Protein: Structural maintenance of chromosomes protein 6B (DNA repair protein RAD18) (AtRAD18) (Q9FII7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Core component of the SMC5-SMC6 complex that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular location: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Associates with chromatin. {ECO:0000250}.
Interaction partners:
- Non-structural maintenance of chromosomes element 4 homolog A
- Non-structural maintenance of chromosomes element 4 homolog B
- E3 SUMO-protein ligase MMS21
- Structural maintenance of chromosomes protein 5
- Non-structural maintenance of chromosomes element 1 homolog
- Structural maintenance of chromosomes protein 3
- Protein CHROMOSOME TRANSMISSION FIDELITY 7
- Condensin-1 complex subunit CAP-D2
- Sister chromatid cohesion 1 protein 1
- ARM repeat superfamily protein
Sequence:
MVKSGARASDSFIKQRSGSGSILRIKVENFMCHSNLQIEFGEWVNFITGQNGSGKSAILTALCVAFGCRARGTQRAATLKDFIKTGCSYAVVQVEMKNSGEDAFKPEIYGGVIIIERRITESATATVLKDYLGKKVSNKRDELRELVEHFNIDVENPCVVMSQDKSREFLHSGNDKDKFKFFFKATLLQQVNDLLQSIYEHLTKATAIVDELENTIKPIEKEISELRGKIKNMEQVEEIAQRLQQLKKKLAWSWVYDVDRQLQEQTEKIVKLKERIPTCQAKIDWELGKVESLRDTLTKKKAQVACLMDESTAMKREIESFHQSAKTAVREKIALQEEFNHKCNYVQKIKDRVRRLERQVGDINEQTMKNTQAEQSEIEEKLKYLEQEVEKVETLRSRLKEEENCFLEKAFEGRKKMEHIEDMIKNHQKRQRFITSNINDLKKHQTNKVTAFGGDRVINLLQAIERNHRRFRKPPIGPIGSHVTLVNGNKWASSVEQALGTLLNAFIVTDHKDSLTLRGCANEANYRNLKIIIYDFSRPRLNIPRHMVPQTEHPTIFSVIDSDNPTVLNVLVDQSGVERQVLAENYEEGKAVAFGKRLSNLKEVYTLDGYKMFFRGPVQTTLPPLSRRPSRLCASFDDQIKDLEIEASKEQNEINQCMRRKREAEENLEELELKVRQLKKHRSQAEKVLTTKELEMHDLKNTVAAEIEALPSSSVNELQREIMKDLEEIDEKEAFLEKLQNCLKEAELKANKLTALFENMRESAKGEIDAFEEAENELKKIEKDLQSAEAEKIHYENIMKNKVLPDIKNAEANYEELKNKRKESDQKASEICPESEIESLGPWDGSTPEQLSAQITRMNQRLHRENQQFSESIDDLRMMYESLERKIAKKRKSYQDHREKLMACKNALDSRWAKFQRNASLLRRQLTWQFNAHLGKKGISGHIKVSYENKTLSIEVKMPQDATSNVVRDTKGLSGGERSFSTLCFALALHEMTEAPFRAMDEFDVFMDAVSRKISLDALVDFAIGEGSQWMFITPHDISMVKSHERIKKQQMAAPRS
Protein: DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (RPB6 homolog) (P61219)
Organism: Mus musculus (Mouse)
Function: DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P61218}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P61218}.
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I and III subunit RPAC1
Sequence:
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIISD
Protein: Reduced expression 2 (Q6NWW4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVLEQDTQHIVNEHGHNRKKSSKCNELRNVIHESSESTPYNTNHRDATLQSSNLKRHKTGTTKGVCTYKDCVNCLKGSSIISLNQGTHIEKKEHNRNKNLDEVLVSRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQTSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQPSHLSIHRRIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCSECDKCFTEKFTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTKPSHLSIHRRIHSGEKPYKCSECDKCFTQPSPLSIHRRIHSGEKPYKCSECDKCFTDKGSLRVHQRIHIGEKPYKCSECDKCFTQPSHLSIHCRIHSGEKPYKCSECDKCFTHKGSLRVHHRIHAGEKPYKCSECDKCFTEKNGLRRHQRIHTGEKPYKCSECDKCFTRKSHLSIHQRIHTGEKLYKCSECDKCFTQQCHLSIHQKIHSGENLTNAMNATNALVTNTV
Protein: Elongator complex protein 6 (Q9VFW4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22645656}. Nucleus {ECO:0000269|PubMed:22645656}. Cytoplasm, cytoskeleton, spindle {ECO:0000305|PubMed:36302967}. Note=Concentrates in the nucleus upon insulin stimulation (PubMed:22645656). During asymmetric cell division of sensory organ precursor cells the elongator complex preferentially binds and stabilizes microtubules on the anterior side (pIIb daughter cell) of the spindle (PubMed:36302967). {ECO:0000269|PubMed:22645656, ECO:0000269|PubMed:36302967}.
Interaction partners:
- Elongator complex protein 5
- Elongator complex protein 4
- Elongator complex protein 3
- Elongator complex protein 1
- TAR DNA-binding protein 43
- Tetraspanin 68C, isoform A
- Elongator complex protein 2
Sequence:
MATSVLLACGLNEQKLPGFVHISEESNVDASFLISCVLGQRLRISNAGTLLVCLQHHYQHYFNAGMRLGYNTNIFQGKTLGVIDVLSDMAGEGLASKWLTNTEGQTLTDQLVEDIRAQVERNYASRNSYTVLIDNLSILFNLGASKLQVQQFCQDLAALGKEREKLTVITKLSNSDIYQLTDNNVAKLGQVRIQVLRLKSGVFREVDGKLLIERVLDEGNYACEETRKEVLYKVNDRNVKVFAPGEIGVKV
Protein: Uncharacterized protein C19C7.05 (O60154)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Probable glycosidase C21B10.07
- Putative mannan endo-1,6-alpha-mannosidase C1198.07c
- SUR7 family protein pun1
- Putative cell agglutination protein pfl3
- Putative cell-type specific agglutination protein pfl7
- Pyruvyl transferase 1
- P cell-type agglutination protein map4
- Pyruvylated Gal-beta-1,3-epitope synthesis protein 5
- O-glycoside alpha-1,2-mannosyltransferase omh1
Sequence:
MNDDSSSSSSGDSSDGSSGTTIVQTNSYPWSAYGRWVVVIICIAALIFFFFIIGIINRRRTKKGQATIPFTNFYPLTAPPPYTAEPEARYNSTIHNPMPPMSQAYRPPPTEPPTVPAYETSSEFPPPAYPEAAATSDAAFRKYDGYAKLG
Protein: Myoblast determination protein 1 (Q02346)
Organism: Rattus norvegicus (Rat)
Function: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Transcription factor E2-alpha
- TATA box binding protein
- Transcription factor 4
- Paired box 7
- F-box only protein 32
- TATA box-binding protein-like 2
- p300/CBP-associated factor
- Mothers against decapentaplegic homolog 3
- Myocyte-specific enhancer factor 2A
- TATA-box binding protein like 1
Sequence:
MELLSPPLRDTDLLGPDGSLCSFATRDDFYDDPCFDSPDLRFFEDLDPRLVHVGALLKPEEHAHFPTTVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDAAYYSEASSEPRPGKSAAVSSLDCLSSIVERISTDSPAAPSLLLPDAPPESPPGPPEETSSSDAEQGTQTPSPDSTPQCPAGSKPNPIYQVL
Protein: Vitamin D-binding protein (DBP) (VDB) (Gc-globulin) (Group-specific component) (P21614)
Organism: Mus musculus (Mouse)
Function: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Subcellular location: Secreted {ECO:0000269|PubMed:10052453}.
Interaction partners:
- Albumin
- Low-density lipoprotein receptor-related protein 2
- Cubilin
- Alpha-2-HS-glycoprotein
- Fibrinogen beta chain
- Protein AMBP
- Fibrinogen gamma chain
- Transthyretin
- Vitamin D 25-hydroxylase
- 1,25-dihydroxyvitamin D
Sequence:
MKRVLVLLLALAFGHALERGRDYEKDKVCNELAMLGKEDFRSLSLILYSRKFSSSTFEQVNQLVKEVVSLTEECCAEGADPTCYDTRTSELSVKSCESDAPFPVHPGTPECCTKEGLERKLCMAALSHQPQEFPTYVEPTNDEICEAFRRDPKGFADQFLYEYSSNYGQAPLPLLVAYTKNYLSMVGSCCTSANPTVCFVKERLQMKHLSLLTTMSNRVCSQYAAYGKEKSRLSHLIKLAQKVPTANLENVLPLAEDFTEILSRCCESTSEDCMASELPEHTIKICQNLSKKNSKFEECCQENTPMNIFMCTYFMPAAEPLQLPAIKLPTGKDLCGQSTTQAMDQYTFELSRRTQVPEVFLSKVLEPTLKTLRECCDTQDSVACFSTQSPLLKRQLTSFIEKGQEMCADYSENTFTEYKKKLAERLRTKTPNTSPAELKDMVEKHSDFASKCCSINSPPLYCSSQIDAEMIDTLQS
Protein: Putative pumilio homolog 7, chloroplastic (APUM-7) (AtPUM7) (Q9C9R6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Subcellular location: Plastid, chloroplast {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:20214804}.
Interaction partners:
- Pumilio homolog 26
- Outer envelope pore protein 24B, chloroplastic
- Probable CCR4-associated factor 1 homolog 5
- Pumilio homolog 24
- Pumilio homolog 23
- Splicing factor, CC1-like protein
- At2g29210/F16P2.41
- Protein trichome birefringence-like 35
- Pre-mRNA-splicing factor 38
- Outer envelope pore protein 24A, chloroplastic
Sequence:
MDEFREASSVSSSPSTPLRTPLHSPNLFNGDFSVSNRFSFKSSSDYSLSSSFSNGLCSPEDSSSPFSSPPFNGIIPKHNHTSSSPVSFDSLFFKDHEKSHVNGTDDLGLCEDLYRMNIKEDVEEDQIRYARTETLKDPLPKSDHTDFTPDPLYNFSPKHYEPSNGGFVSGGFPYGFFRPPKESSINQSCASWSGFDQSKNDDKRNMFGNNPQQFGWPSYSSSNSGTSPYNNGQEIFENRGGMREYSAYSPPHQPEVSYKHQNYRTTTSDILPLFCQRTQVPMVSKCSEPFSSDESFFMNGKSIDHQRSNTRALMSNNGNPTEICHPSLPNMCDIQGYVYLMAKDQHGCRFLQRIFDEGTSVDAMIIFNEVIAHVVELMMDPFGNYLMQKLLDVCTEEQRTQIVLVATEEPGQLIRISLNAYGTRVVQRLVETIRSGKQISLVKLALRPGFLDLIKDLNGNHVIQRCLQCLSTEDNKFIFDAATKFCTEIATHRHGCCVLQKCIAYSMRQQREKLIAEISRNSLLLAQDPFGNYAVQFVIELRIPSAVAMMLAQLKGHYVQLSMQKFSSHMVERCLMHCPESRPQIVRELVSVPHFDQLLQDPYANFVIQAALAATKGPLHASLVEVIRPHSILRNNPYCKRIFSRNLLKK
Protein: Anoctamin (F1M3G8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU280814}.
Interaction partners:
Sequence:
MDPEHLPVINNYLDANEPASSEARLSRMHFHDNQRKVDYVLAYHYRKRGAHLGHGSPGHSLAVISNGETGKERHGGGPGDIELGPLDALEEERREQRDEFEHNLMAAGLELEKDLESKSQGSVFVRIHAPWQVLAREAEFLKIKVPTKKMYEIKAGGSIAKKFSAILQTLSSPLQPRVPEHSNNRMKNLSYPFSREKMYLYNIQEKDAFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPGDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSKEMCDHQNAFTMCPLCDKSCDYWNLSSACGTARASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEEHSRPEYETKVREKLLKESGKSAVQKLEANSPEDDEDDEDKLTWKDRFPGYLMNSVSILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEPGESDPDHSKRPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVIINAFVIAVTSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWSVLSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKVKLADEPAQRSQGGGNRSRRSRAASSAPSGRSQPGSIASSGSQHTNV
Protein: Pheromone-processing carboxypeptidase kex1 (EC 3.4.16.6) (Carboxypeptidase D) (O60123)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Vacuole membrane {ECO:0000269|PubMed:16823372}; Single-pass type I membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Dibasic-processing endoprotease
- Bax inhibitor 1
- Probable CAAX prenyl protease 2
Sequence:
MISKLLKIVLLTAGVIGNTLADSRIHEQYLVKAFPNEPVDYEGRMHAGHLNQTDQLDGDLFFWMFESVKPEYEHRSILWLNGGPGCSSEDGSLMEVGPFRLDDNNTFQLNPGRWDELGNLLFVDQPLGTGYSYSLAKDFQSNNEKMANDFSIFFEKFLEEFPERANDEWFIAGESFAGQYIPHIAAKLKEKNLVNLGGLAIGNGWINPLSHYETYLNYLVEKGMVDFESELGQYLHHSWAECLLAFDKIGSGSGDLSKCESFLGDILYMVSKEPGKACMNMYDISLESTYPTCGMDWPYDLSYLTEFLSTREAMTSLNVNLEKVHDWEECNDDVALQYAREGIESSSKLIQDLVSTVPILLFYGENDFLCNYLSGEKLTRSLEWNGAVGFQNQSAQPFYLPGYSDQPSGSYVSSRNLTFARIVEASHMVPYDHPNEMKTLITAFFNNDFASLPSVPKPSPDLGNGNYKWLYLGLIPVALTIIILFSIYLCRRFGLFGLSKQRYQPISPTP
Protein: Large ribosomal subunit protein uL2cz/uL2cy (50S ribosomal protein L2, chloroplastic) (Q6EN83)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL5c
- 60S acidic ribosomal protein P1
- 60S ribosomal protein L35a
- Large ribosomal subunit protein bL27c
- KOW domain-containing protein
- Uncharacterized protein
- Large ribosomal subunit protein uL3c
- Uncharacterized protein
- Ribosomal protein L30 ferredoxin-like fold domain-containing protein
- Ribosomal protein L30 ferredoxin-like fold domain-containing protein
Sequence:
MAKHLYKTPIPSTRKGTIDRQVKSNPRNNLIHGRHRCGKGRNSRGIITARHRGGGHKRLYRKIDFRRNQKDISGRIVTIEYDPNRNAYICLIHYGDGEKGYILHPRGAIIGDTIVSGTKVPISMGNALPLTDMPLGTAIHNIEITRGRGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLVSQNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGKAPIGRKKPTTPWGYPALGRRTRKRKKYSDSFILRRRK
Protein: BAG family molecular chaperone regulator 8, chloroplastic (Bcl-2-associated athanogene 8) (Q9LIB3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Protein WVD2-like 4
- Glycosyltransferase
- Uncharacterized protein
- HEAT repeat-containing protein
- O-fucosyltransferase 15
- Reticulon-like protein B5
- Serine/arginine-rich SC35-like splicing factor SCL30
- non-specific serine/threonine protein kinase
- WAT1-related protein At1g44800
Sequence:
MASHHHHNHNHVCSRHQNHHNNTPQFATSPNCCNKSNHPSPPPAEDNLLHLVATYLQNHQQETQCSCETSCQNFNVIRSQNRVLRQHKNVPREYDQVVLSCLLRKIDDLESSLNKFSSFYDKRRDRHSTLRDSAARVIQTHFRSYLVHRSISFRQLKELAMIKASFLSLKSSVSGKLIFPFKVVSRKATDLLLQLDSIQGRIDPMIRSSKRSLSRDLVRFVQYVDDCVVKRYGFVVKSGSGIKLNGKKPQGFGTSSEDEDNNADMSDDSEEVPVSSIDKRKVASSKSRTGVVIEGDVVKPPVMKFVVLDKNRNVCQVYGNRHDLTSSAEDDSVDGDEETLVMSRDNGRKQSLKARNGVSVKGGGGKTTRVVKTVSFDENGNVCKVYGDTHDLTSSAEDDDSVDVGEETLVMCRDEGKRRSSKTGSRVLVKGSGGKTNRVVKTVSFDENGNVYKAYGDTPESSIISEEDDSTSGSNEGNGEEKGNVNEVEEIKYVPKENESFEEEEEKETDSENEVSSSEGSEGDKRVTKKEVQHQKGSLMFSPPLPLKMEP
Protein: Core-binding factor subunit beta (A0A140LGT1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Runt-related transcription factor
- Runt-related transcription factor.
- Runt-related transcription factor.
- Activation-induced cytidine deaminase.
- Cullin-5
- Cullin-5
- Elongin-C
- Elongin-C
- Elongin-B
- Uncharacterized protein.
Sequence:
MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVATGTNLSLQFFPANLHGDQRQAPTREYVDFERETGKVYLKAPMILNGVCVIWRGWLDLHRLDGMGCLEYDDERAQHEDALAQAAFEEARRRTRDFEDRDRSHREDLEQMPMAQLNHLITQEPRRQQDPSPGSNMGNTDDHKMR
Protein: Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta) (P53612)
Organism: Mus musculus (Mouse)
Function: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.
Interaction partners:
- Geranylgeranyl transferase type-2 subunit alpha
- Rab proteins geranylgeranyltransferase component A 1
- Protein prenyltransferase alpha subunit repeat containing 1
- Rab proteins geranylgeranyltransferase component A 2
- Protein tyrosine phosphatase type IVA 2
- Synaptobrevin homolog YKT6
- Ras-related protein Rab-1A
- Ras-related protein Rab-1B
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Ras-related protein Rab-3A
Sequence:
MGSLLFSWKGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNREEILVFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSVHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS