wanglab/gogpt-training-data huggingface dataset:
Protein: Probable disease resistance protein At5g45510 (Q8VZC7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable disease resistance protein.
Interaction partners:
- Disease resistance protein
- Powdery mildew resistance protein, RPW8 domain-containing protein
- Probable disease resistance protein At5g45490
- Disease resistance protein
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Disease resistance protein RPP1-WsB, putative domain family protein)
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Disease resistance protein
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Probable disease resistance RPP8-like protein 2
Sequence:
MSDPLKMAAETEEIKPVPAAMGEKKDVVLCKKIVETLGGGGDQRVLLVGEAGIGKTRMAQMVDKEASKDVLCYQTLWLHLNRKFKVNDNYIKEKKFEDEWSLYENIASQLSLYSDFEETEVGERDEDEEEEKKVEDLLKDLKPKIEKYLLEKKEAVVKKLEDDKKKKEKEAAEKLEAEKKLVDPAAKKAKDHGNKNPTDAAKEKTTQVVAGGEDKAQTSSERKPYLLLILDDEGMTSEYEVMVHLGLEDFLKDHTPRKILITRRQETEEATKSGEHAEGEANDSQSGEKKEDTDGEDEIRSADKEEPESQARVKTEEKHEKVVPPTIDDLWGSTNTYGEITFQTTNESQDLLESFNLKEAEALFTSSMFFKDMPNFFFDPVPGTDEKLLNHMLKKSKSLPAAINVLAKSLEYTVKSKSYKLNKDEEERLLKEKIEMVLSAERGNPSDQESSSESPKKASGENPILLLAYKLFKTDGPLKDTILDCFWHSLDFFEHCGCVYYRDLITQWILEGYFDPVRSVEKAYQDGHSIFMELIDRGMLKIQENNVVVPEMAMRNVIDPRRGGHLGKSRLGFSRVYGGNKRKGIGKITQLDDMIKTVQAKKGDKITTILVSGDRLRRVTPKKFFKNLKELEVLGLFEPTVKPFVPSFSDQLKLLRVLIIRDCDLLKSIEELKALTKLNTLEVSGASSLSKISEKFFESFPELRSLHLSGLKIESSPPSISGLKELHCLIIKDCPLLQDLPNIQELVNLEVVDVSGASGLRTCFDNADGAKKNKSKNKNFYLLTKLQHLDFSGSQIERLPIFQDSAVAAKLHSLTRLLLRNCSKLRRLPSLKPLSGLQILDLSGTTSLVEMLEVCFEDKLELKTLNLSGTNLSELATTIEDLSSLNELLLRDCINLDAIPNIEKLENLEVIDVSGSAKLAKIEGSFEKMFYLRVVDLSGTQVETPELPADTKIHCLKRFTRADGKCFERDTWREIKEDIERDRSENASSSDAVVISQEITEKKPVEIREVESNAPRASDCTEKVDVNKERLLKVPIDRALYQKALTSLVDSKIPQEEVLEINETNKLDEEALASAEFVSFVDCTPERVKSIFEKAKLVKGCWLRMCFDIKDPFDGVDEENLKSLETLSITNLLSLETISFIAKLENLKNLSLDCCPKIKTIFPEMPASLPVLNLKHCENLEKVVVGVEVSTHTNLDLKVENCPKFGDYVMVDHSDVPPPHEC
Protein: Cathelicidin-derived antimicrobial peptide 1 isoform b (A0A0F6QEW3)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MKMKVQVRSLILLAVAVLQVRSQNQTETRYEDIILVALPQLLPGEEQAFRPILNQLQVKTLNTEDVDQSEVSVRLTFPIQETFCSKSQGQPGKPCPLKKNGKLMMCSMKVRHPILEASNNLNTDLSTFVCEYMDAEDALQQKIRTRRSKVRICSRGKNCVSRPGGGSVIGRPGGGSPPGGGSFNDEFIRDHSDGNRFA
Protein: ABC transporter, putative (Q4GYD6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTTTQGEVISTTFFSSKALLKSLQDVSRSLHISGNQFLPPNTVLLCAVGLGFLVDGVYTATVWFRNRRALNVERAVNHHNGPVKFVVTDELEDRDEEAKACLVQQYSDELCKAILGAPRTSPGSWARSPPADAVAEYETLPEPIRLLWEDRVRYTLDAREVVGLLRRRLEPHLAGSRYGPSAALMALLWRLQLLRTVHESIVIAGDVGRCNAELTELGKHTGALYREFISTLHAPVRVPFDSCWECLSAEDDRLRGQARALQLRNLWSLTRYVFAGGLDKLCTYGMVGLLTAFAARSASAICTIRVDVEQLLPNLFGTAASINTGGTTGDGAIVSWTAMHIVVARLLVSEWMLHMLRLGITRVTQDYTHASAAWRRDTVKHRLYDALTRTPLSYFDKTERYAVEEIVYYVNDLEGVDVFVHDFFTRLAQSGISLCVALRVLDMRSAVTVMGAVAGASLLNASLSFLKKTYCALSYCNGIGFEAVDSPSDAEEEENRKDTTDHLMFCGMDIIEHIPELRPYGADTKLMEWWNNYTAHYRRRSCGLRRVFQLTYNSRYLWAIDALKPVARWLLPAIVAANAAGTCQIQVFLLEAIRASQDVLERVVDVQRVVDVVGYNAYKAGVLERILDSKNWEDGDTAERICEHTNKGNISDTTALTCDMNGGTYKKNKEDGELRLKGNDVEVLAVRANGLQFRYPTAPTVDAFLKPASFQFELRNRTTGLGRLVCITGVSGCGKTTLLRLLLGLYAPENPNTLLLEFRLRRHHVSESNGGGTGNSGNKEQWAPVELIPRAQLRSTFFSYVPQAPTIFPGATIAQNVSLRNRVSITDTLVLERVRVCTEAAGCGHFIKRLPNGIMTPLCVNVGWATPDAVRLSCGQGQRLMLARALFHCSSVLLLDEPTAGLDSETKKAVMSQWRELLSSGLVGGIICVSHDADVLQMADETVTL
Protein: Baseplate wedge protein gp7 (Gene product 7) (gp7) (P19061)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Intermediate/inner baseplate protein. The gp25-(gp6)2-gp7 module is involved in sheath contraction. Involved in the tail assembly.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04103, ECO:0000269|PubMed:15315755, ECO:0000269|PubMed:2254933, ECO:0000269|PubMed:2403438, ECO:0000269|PubMed:27193680}. Note=Present in 6 copies in the baseplate. {ECO:0000303|PubMed:21129200}.
Interaction partners:
Sequence:
MTVKAPSVTSLRISKLSANQVQVRWDDVGANFYYFVEIAETKTNSGENLPSNQYRWINLGYTANNSFFFDDADPLTTYIIRVATAAQDFEQSDWIYTEEFETFATNAYTFQNMIEMQLANKFIQEKFTLNNSDYVNFNNDTIMAALMNESFQFSPSYVDVSSISNFIIGENEYHEIQGSIQQVCKDINRVYLMESEGILYLFERYQPVVKVSNDKGQTWKAVKLFNDRVGYPLSKTVYYQSANTTYVLGYDKIFYGRKSTDVRWSADDVRFSSQDITFAKLGDQLHLGFDVEIFATYATLPANVYRIAEAITCTDDYIYVVARDKVRYIKTSNALIDFDPLSPTYSERLFEPDTMTITGNPKAVCYKMDSICDKVFALIIGEVETLNANPRTSKIIDSADKGIYVLNHDEKTWKRVFGNTEEERRRIQPGYANMSTDGKLVSLSSSNFKFLSDNVVNDPETAAKYQLIGAVKYEFPREWLADKHYHMMAFIADETSDWETFTPQPMKYYAEPFFNWSKKSNTRCWINNSDRAVVVYADLKYTKVIENIPETSPDRLVHEYWDDGDCTIVMPNVKFTGFKKYASGMLFYKASGEIISYYDFNYRVRDTVEIIWKPTEVFLKAFLQNQEHETPWSPEEERGLADPDLRPLIGTMMPDSYLLQDSNFEAFCEAYIQYLSDGYGTQYNNLRNLIRNQYPREEHAWEYLWSEIYKRNIYLNADKRDAVARFFESRSYDFYSTKGIEASYKFLFKVLYNEEVEIEIESGAGTEYDIIVQSDSLTEDLVGQTIYTATGRCNVTYIERSYSNGKLQWTVTIHNLLGRLIAGQEVKAERLPSFEGEIIRGVKGKDLLQNNIDYINRSRSYYVMKIKSNLPSSRWKSDVIRFVHPVGFGFIAITLLTMFINVGLTLKHTETIINKYKNYKWDSGLPTEYADRIAKLTPTGEIEHDSVTGEAIYEPGPMAGVKYPLPDDYNAENNNSIFQGQLPSERRKLMSPLFDASGTTFAQFRDLVNKRLKDNIGNPRDPENPTQVKIDE
Protein: Variant surface glycoprotein (VSG), putative (Q57UD8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MSVATTALMILMTKWAANTASATGEPLLGKTWKPPCAIAKELRKVPVMAYTHESNLQDAITAAERTAAKLNLYAATTQSDVETTALLSAAAAAIYEEADASERQRSNFIKTALEATATTQELTGGIEASLQVFKSAKHSGGYCLADTDTDEDKTADIATAGCEQRPKTMKKTPSETLDADIISATGFKTIDEITGTNGMATSVSTKCGLVNFAGAGTGAFVTGATAVNFGYGLFKIATTNRVTRTSQQNLKKQTNRDADDLLTLAFNDADTIRAAITQQLAHEPEAIIKAAVTTGKLKGHLTKLLHKLYGKQAGKQAEDKAEVLIKENFGEAGEKVKSFLNKLDEADAINVDPSATTNTKIKEINDAGILQVTLAFYKILEVKHKQQMADQVAKLQAQATEKQQDVKSAEQTCNDLKEKSDCDTNNRCTYDKTKEDGKKCTLSDEEKEAAQKEGGEKDSKTGNTNTTGSNSFVINKAPLLLAFLLF
Protein: Intelectin 1 (A0A2R8QEW4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MMQSAGFLLLCVPLISLLCESSKTPTGEFPESVTARSCRELLKKYGHKKDGLYYLRSKDNEVYQTYCDMSTNGGGWTLVASVHENNIHGSCTVGDRWTSQQGSSSYHPAGDGSWSNKVLFGTAEAATNDDYKNPGYYDIKAKDIAVWHVHNDNELEFWKVASVLRYHTNSNFLTPFGGNLYHFFKKYHLQYGIGTCNDRGISVPIVYDIGSDMRVNELYGESVRADFDTGYVTFRVFNNYQEAYAMCSGVRPKGCYAQYYCIGGGGYFPNTFCSDFAYLNANNGATNGYGASKEIINAAVFIFYR
Protein: Ubiquitin-like-specific protease 1C (EC 3.4.22.-) (Protein OVERLY TOLERANT TO SALT 2) (Q8RWN0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins. Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5. Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3. Protease activity mainly directed at deconjugating SUM1 and SUM2 from their target proteins. Regulates salt stress responses and flowering time. Redundant with ULP1D.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:18849491}.
Interaction partners:
- Small ubiquitin-related modifier 1
- Small ubiquitin-related modifier 2
- Small ubiquitin-related modifier 3
- SUMO-conjugating enzyme SCE1
- Small ubiquitin-related modifier 5
- SUMO-activating enzyme subunit 2
- E3 SUMO-protein ligase SIZ1
- E3 SUMO-protein ligase MMS21
- E4 SUMO-protein ligase PIAL1
- SUMO-activating enzyme subunit 1A
Sequence:
MKRQRAIELDRVKKTMLNIDWDDALGDEEVPELEIIATDKIPPREPTLSGYEPAVSVRSLRDNELDDHLKRQRSLLTRLGDKLADKGEKIRNRIGELEYEKQRRMFQQRTKMQDADNGCQILEKPKSSDVFMRASTASKDTSGQGTSGSKDVSRSTFAAHFSDNLKMGPQPVKLVNDKLQDLGRGSWISKANRDSIIEKNNVWRSLPRLSKCKVSLKNFYSESKDPKGDRRPNEAYGKGKPNESSPYLLVDDDDGDDDKVIGYETPRHWSLKASPLQSSSCRKKSDDKVINLDEDEPLSPMVVEEACELPEGLPEDIYYPSSDQSDGRDLVQVSLKDLKCLSPGEYLTSPVINFYIRYVQHHVFSADKTAANCHFFNTFFYKKLTEAVSYKGNDRDAYFVKFRRWWKGFDLFCKSYIFIPIHEDLHWSLVIICIPDKEDESGLTIIHLDSLGLHPRNLIFNNVKRFLREEWNYLNQDAPLDLPISAKVWRDLPNMINEAEVQVPQQKNDFDCGLFLLFFIRRFIEEAPQRLTLQDLKMIHKKWFKPEEASALRIKIWNILVDLFRKGNQTD
Protein: Large ribosomal subunit protein uL23cz/uL23cy (50S ribosomal protein L23, chloroplastic) (P0C451)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Binds to 23S rRNA.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Os05g0214400 protein
- Os07g0190900 protein
- FHA domain containing protein, expressed
- Os02g0708600 protein
- Os02g0708500 protein
- Putative MYST-like histone acetyltransferase 1
- Os05g0469825 protein
- Os09g0530600 protein
- Os03g0607800 protein
- Os07g0405100 protein
Sequence:
MDGIKYAVFTEKSLRLLGKNQYTFNVESGFTKTEIKHWVELFFGVKVVAVNSHRLPGKGRRMGPILGHTMHYRRMIITLQPGYSIPLLDREKN
Protein: ARS-binding factor 2, mitochondrial (Q02486)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Specific binding to the autonomously replicating sequence 1 (ARS1). Interaction with regulatory regions: probably involved in compacting the mitochondrial genome. It might play a positive role in gene expression and replication.
Subcellular location: Mitochondrion. Nucleus {ECO:0000305}.
Interaction partners:
- Non-histone chromosomal protein 6A
- Cruciform cutting endonuclease 1, mitochondrial
- DNA-directed RNA polymerase, mitochondrial
- Ketol-acid reductoisomerase, mitochondrial
- Mitochondrial genome maintenance protein MGM101
- Aconitate hydratase, mitochondrial
- Non-histone chromosomal protein 6B
- Non-histone protein 10
- Large ribosomal subunit protein mL67
- Putative uncharacterized protein Q0092
Sequence:
MNSYSLLTRSFHESSKPLFNLASTLLKASKRTQLRNELIKQGPKRPTSAYFLYLQDHRSQFVKENPTLRPAEISKIAGEKWQNLEADIKEKYISERKKLYSEYQKAKKEFDEKLPPKKPAGPFIKYANEVRSQVFAQHPDKSQLDLMKIIGDKWQSLDQSIKDKYIQEYKKAIQEYNARYPLN
Protein: Cell wall integrity and stress response component 4 (P38739)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MQTSMVSAKVSIWLVCSVICSSLVRATQSVCSSQNTATTDGVRNQFQSNGWCSNNCAGHQFAIVQGFMCWCSDSEPSTQTSVGDCSGTCPGYGYEDCGNADKDLFGYIYLGQTPLSSVQSVETSTESSVYVSSSSITSSSSTSIVDTTTISPTLTSTSTTPLTTASTSTTPSTDITSALPTTTSTKLSTSIPTSTTSSTSTTTSTSSSTSTTVSVTSSTSTTTSTTSSTLISTSTSSSSSSTPTTTSSAPISTSTTSSTSTSTSTTSPTSSSAPTSSSNTTPTSTTFTTTSPSTAPSSTTVTYTSTTASPITSTITSVNLQTSLKYSVITVTSVHTMDTNISEITSRYLTMKKVITQIYSSTLGATPTSAVATTSASVGGRITNNNNSNTTNSNTPTNKSTEKKGYWDSPGKIAATFVVVGVVCLVIICILIYLIHHYRTRPARKAQDFENEYQSKFYQSKYPNEVTTTTLHTPSPSSNSTFSTPRLIYTDEKGQIMSESPSPRQSTYSLTAGSPPNDPSTLASPFHDPILPRRTSTFLHSPIQKQHEKMESNVTLGEDTVLVDQRLDPSKMLNTLANDDATNHSTISLSDNVDYSRRVLRLMNE
Protein: Glycine-rich RNA-binding protein RZ1B (AtRZ-1a) (O22703)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds RNA and DNA sequences non-specifically. May be involved in tolerance to cold stress.
Subcellular location: Nucleus {ECO:0000269|PubMed:20850334}.
Interaction partners:
- Serine/arginine-rich splicing factor SC35
- Serine/arginine-rich SC35-like splicing factor SCL30
- Glycine-rich RNA-binding protein RZ1C
- Eukaryotic translation initiation factor 2 subunit alpha homolog
- DExH-box ATP-dependent RNA helicase DExH12
- B3 domain-containing transcription factor VRN1
- Glycine-rich domain-containing protein 2
- Serine/arginine-rich splicing factor SR30
- Gb|AAD20086.1 family protein with RNA binding
- Nuclear speckle RNA-binding protein A
Sequence:
MKDRENDGNLESRIFVGGLSWDVTERQLESTFDRYGKITECQIMVGRDTGRPRGFGFITFTDRRGADDAIKHMHGRELGNKVISVNKAEPKVGGEDVDQLKKGGGYSSRGKGTEDECFKCRRPGHWARDCPSTGDDRERFRVPLAMRSRIGDIDGHRDRYGDRDLEREREREREFDRYMDGRRDRDGGRYSYRDRFDSGDKYEPRDHYPFERYAPPGDRFVSDRYGMPEHHLENEYRGRERSYDRDRYARDTSDRYGDMGPIRDEGRPYRSRPGPYDRPSRPGGRPSSYERW
Protein: AD domain-containing protein (O01871)
Organism: Caenorhabditis elegans
Interaction partners:
- ATP-dependent RNA helicase
- Gem-associated protein 2
- Uncharacterized protein F10E9.5
- Gem-associated protein 7
Sequence:
MSNDQIWDLLGHQIQIELDTGDVRRQESTTGHLMTRDPVSQSLLIAKIEENSTSIKSIEWIPSCSVKSIRKLKNTENPEIHVAIEKYFENDGIEGGSSGAEDSEEDIKKRAHRVVNYLKSHHLDVVEKPNGTYIIAGTVRFERPYHNANLYCDIPIVLKRILKLVEEI
Protein: Putative RNA-binding protein (RRM domain-containing protein) (G5EE68)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Sex determination protein fox-1
- JNK-interacting protein
- RRM domain-containing protein
- Muscleblind-like protein
- V-type proton ATPase 116 kDa subunit a 1
Sequence:
MGQQQHEMRASSTSSTDSNGFPVKDPDAIKLFVGQIPRNLEEKDLRHLFEQFGKIYEFTILKDKYTGMHKGCAFLTYCHRDSAVRCQATLHDQKTLPGMNRAMQVKPADTDSRPASPKDKMDDKKLFIGMLSKQQSEDEVRALFATFGELDEVTVLRGADGASKGCAFVKYKHGLDAHMAISALHGSQTMPGASSSLVVKYADTEKERQNRRMQQMAAQMGMLNPMLVNQVGMQYNAYQQVLQQQSLAAQTNAMASAAYLPLLQQQTTDPLHVLQLQAAAAAAQAAANPVLSQQTQQQQQQQQQLAAQLQLQSAAAQNPHYALAAQALAQQQAAQQAQAVVAHSHAQVHQHQTAQVTSTASHAQTENPAASSYGSLAAAAAAANYSSLLSGMESQHNAAAALQLAQIQQQAAAALPMVTPREVLGPDGCNLFIYHLPQEFGDAELIQMFAPFGHIVSAKVFVDRATNQSKCFGFVSYDNIHSSQAAITAMNGFQIGMKRLKVQLKRPRNESRPY
Protein: Interferon gamma inducible protein 47 (A0A1L1SQM2)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDQFISAFLKGASENSFQQLAKEFLPQYSALISKAGGMLSPETLTGIHKALQEGNLSDVMIQIQKAISAAENAILEVAVIGQSGTGKSSFINALRGLGHEADESADVGTVETTMCKTPYQHPKYPKVIFWDLPGTGTPNFHADAYLDQVGFANYDFFIIISSSRFSLNDALLAQKIKDAGKKFYFVRTKVDSDLYNE
Protein: Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.3.6) (CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (ST3GalVI) (Sialyltransferase 10) (Q9Y274)
Organism: Homo sapiens (Human)
Function: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Alpha-
- N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
- Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
- 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3
- Beta-1,4-galactosyltransferase 4
- N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
- 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
- Galactoside alpha-
- Beta-1,4-galactosyltransferase 1
- N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
Sequence:
MRGYLVAIFLSAVFLYYVLHCILWGTNVYWVAPVEMKRRNKIQPCLSKPAFASLLRFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLTQD
Protein: Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) (P60843)
Organism: Mus musculus (Mouse)
Function: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P60842}. Cell membrane {ECO:0000250|UniProtKB:P60842}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:P60842}. Note=Colocalizes with PKP1 in stress granules following arsenate or hydrogen peroxide treatment. {ECO:0000250|UniProtKB:P60842}.
Interaction partners:
- Eukaryotic translation initiation factor 4 gamma 1
- Eukaryotic translation initiation factor 4 gamma 3
- Eukaryotic translation initiation factor 4 gamma 2
- Eukaryotic translation initiation factor 4B
- Programmed cell death protein 4
- Eukaryotic translation initiation factor 4E
- Eukaryotic translation initiation factor 4H
- Polyadenylate-binding protein 1
- Eukaryotic translation initiation factor 5
- Eukaryotic translation initiation factor 3 subunit B
Sequence:
MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI
Protein: Protein AAL-toxin resistant 7 (Alternaria alternata f.sp. lycopersici toxin resistant protein 7) (Q9C589)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000269|PubMed:31250033}.
Interaction partners:
- Uncharacterized protein T2H7.3
- Ceramide synthase LOH2
- Proline-rich protein 1
- Uncharacterized protein At1g21520
- Transcription regulator-like
Sequence:
MVRSNKQEPRVSSTYIRSLVKQQLAYSTTMTTTTTTTTNDGSGGGKTQTQTHKKQVRRRLHTSRPYQERLLNMAEARREIVTALKQHRASMRQATRIPPPQPPPPPQPLNLFSPPPPPPPPDPFSWTNPSLNFLLPNQPLGLNLNFQDFNDFIQTSSTTSSSSSSSTSSSSSSIFPTNPHIYSSPSPPPTFTTATSDSAPQLPSSSNGENNVVTSAWWSELMLKTVEPEIKPETEEVIVVEDDVFPKFSDVMEFPSWLNQTEEELFHPYNLTDHYSSSPHNPPLSCMEIGEIEGMDGDDWLA
Protein: SLAIN motif-containing protein 1 (Q8ND83)
Organism: Homo sapiens (Human)
Function: Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21646404}. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules. {ECO:0000269|PubMed:21646404}.
Interaction partners:
- Ubiquitin-like protein FUBI
- Cytoskeleton-associated protein 5
Sequence:
MMAEQVKCASAGVSSGAGSGPVVNAELEVKKLQELVRKLEKQNEQLRSRAASAAAAPHLLLLPPPPPAAPPPAGLQPLGPRSPPAATATAAASGGLGPAFPGTFCLPSPAPSLLCSLAQPPEAPFVYFKPAAGFFGAGGGGPEPGGAGTPPGAAAAPPSPPPTLLDEVELLDLESVAAWRDEDDYTWLYIGSSKTFTSSEKSLTPLQWCRHVLDNPTPEMEAARRSLCFRLEQGYTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASVSRHSSSVSLSSGKKGTCSDQEYDQYSLEDEEEFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRECRRSPSSQYFPSNNYQQQQYYSPQAQTPDQQPNRTNGDKLRRSMPNLARMPSTTAISSNISSPVTVRNSQSFDSSLHGAGNGISRIQSCIPSPGQLQHRVHSVGHFPVSIRQPLKATAYVSPTVQGSSNMPLSNGLQLYSNTGIPTPNKAAASGIMGRSALPRPSLAINGSNLPRSKIAQPVRSFLQPPKPLSSLSTLRDGNWRDGCY
Protein: Dof zinc finger protein (Q2V4Q1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00071, ECO:0000256|RuleBase:RU369094}.
Interaction partners:
Sequence:
MAFPSNWSQPTNSNHQHHLQHQLNENGSIISGHGLVLSHQLPPLQANPNPNHHHVATSAGLPSRMGGSMAERARQANIPPLAGPLKCPRCDSSNTKFCYYNNYNLTQPRHFCKGCRRYWTQGGALRNVPVGGGCRRNNKKGKNGNLKSSSSSSKQSSSVNAQSPSSGQLRTNHQFPFSPTLYNLTQLGGIGLNLAATNGNNQAHQIGSSLMMSDLGFLHGRNTSTPMTGNIHENNNNNNNENNLMASVGSLSPFALFDPTTGLYAFQNDGNIGNNVGISGSSTSMVDSRVYQTPPVKMEEQPNLANLSRPVSGLTSPGNQTNQYFWPGSDFSGPSNDLL
Protein: CCR4-NOT transcription complex subunit 11 (Q581Y6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- CCR4-NOT transcription complex subunit 10
- Cell differentiation protein, putative
- Uncharacterized protein
- NOT2/NOT3/NOT5 C-terminal domain-containing protein
- NOT1
Sequence:
MVVEYLGPADVQRLLALLSEGNCKFSFVEKEFKETFSKDTFAKVSRAIQRMIHDMIASPDGVGLVSSFFVLDVMCKMNCEQAKSAFYDALLELERIMRQDVCVMEQIKYASKEAKEGRRAHESVNSERYRLRSAVKSFAFRLLANRVAPDETPLMAISDKQEQIDTALNAWESNSICLKEPIAGVAEAWTLEAEKNACGTLSRISATLDNGGRAALVLKPVTPQLPSLSLVSGELQFLLPASPLNDLLLINSEVPTEEWKTAKRMVAAGCKGLLNKEEQQKLLQTLLAGDVFARVGISSVVLSRMAEHNPDVAASLILKLPAQEANQCVQSILKSSVPSEHVETVLLHASKVLQQASFRAYITNKLHHFKEKTTLSNEDKDEVKNFVRTLHQLLTKASKENKELYVADTLKTDITRLCERCDIPEVVTRWDELK
Protein: Translocating chain-associated membrane protein 1 (Protein TRAM1) (Q15629)
Organism: Homo sapiens (Human)
Function: Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel. Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER. May affect the phospholipid bilayer in the vicinity of the lateral gate of the SEC61 channel, thereby facilitating ER protein transport. Intimately associates with transmembrane (TM) domain of nascent membrane proteins during the entire integration process into the ER membrane. Associates with the second TM domain of G-protein-coupled receptor opsin/OPSD nascent chain in the ER membrane, which may facilitate its integration into the membrane. Under conditions of ER stress, participates in the disposal of misfolded ER membrane proteins during the unfolded protein response (UPR), an integrated stress response (ISR) pathway, by selectively retrotranslocating misfolded ER-membrane proteins from the ER into the cytosol where they are ubiquitinated and degraded by the proteasome.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12475939, ECO:0000269|PubMed:1315422, ECO:0000269|PubMed:20430023, ECO:0000269|PubMed:8616892, ECO:0000269|PubMed:9506517}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Translocon-associated protein subunit beta
- Translocating chain-associated membrane protein 1-like 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Protein transport protein Sec61 subunit alpha isoform 1
- Translocon-associated protein subunit alpha
Sequence:
MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTSNVADSPRNKKEKSS
Protein: Large ribosomal subunit protein uL5c (50S ribosomal protein L5, chloroplastic) (O04603)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- At1g43860
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Large ribosomal subunit protein uL3c
- Large ribosomal subunit protein uL6c
- 50S ribosomal protein L33
- Large ribosomal subunit protein bL28c
- Small ribosomal subunit protein uS9c
- Putative ribosomal protein L6
- Large ribosomal subunit protein bL27c
- Large ribosomal subunit protein eL38z/eL38y
Sequence:
MASPSLLQSSASSFHGRFSPLAAPSSARMLSPPLRNVVKVSASGTVLVEKSEAEKTQRLKTAYLERIIPALKEEFKYVNIHQVPKVQKIVVNCGIGDAAQNDKGLEAAMKDIALITGQKPIKTRARASIATFKIREDQPLGIAVTLRGDVMYSFLDRLINLALPRTRDFQGVSPSSFDGNGNYSIGVKDQGVFPEIRFDAVGKTRGMDVCISTTAKSDQEGQKLLALMGMPFREGGGGSTGAIVRKKKLKSHHFDAKGKGKR