wanglab/gogpt-training-data huggingface dataset:
Protein: Hedgehog protein (A3KNS3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}. Secreted {ECO:0000256|ARBA:ARBA00004613}.; SUBCELLULAR LOCATION: [Sonic hedgehog protein]: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU280812}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU280812}.; SUBCELLULAR LOCATION: [Protein hedgehog N-product]: Cell membrane {ECO:0000256|RuleBase:RU280812}; Lipid-anchor {ECO:0000256|RuleBase:RU280812}.
Interaction partners:
Sequence:
MRLPVVFGLLVGCALIFAPVNEGCGPGRGHGKRRPPKKLTPLNYKQFSPNVAEKTLGASGRIEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNSLAISVMNMWPGVKLRVTEGWDEDGNHFEDSLHYEGRAVDITTSDRDRNKYGMLARLAVEAGFDWVYYESKAHIHCSVKSEHSVAAKTGGCFPASALVTIEDGRLKTLESLQPGEKVLASSESDGSGTLVYSEVIAFLDRDPSARKQFFTIETDSGAKLSLTAAHLLFVSEGNCSGSAANAELRSVFASDVLPGQCVVSTQAAGQHGRLSRVSRIRMQEDRGVFAPLTSHGTVVVNGIVSSCYAAVDQHWLAHWAFGPLRVLYNWGGPVGHQVTGIHWYSSLLHWIGTQVLDPAHFHPWSMMDNDR
Protein: Beta-1,3-glucan-binding protein (GBP) (Q8N0N3)
Organism: Penaeus monodon (Giant tiger prawn)
Function: Binds to beta-1,3-glucan. May play a role in recognition of microorganisms and in activation of the prophenoloxidase cascade.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MKGFVASVVLLACGALAADIVEPEDCTSFPCMIFEDNFDYLDNDIWEHEITMSGGGNWEFQAYVNNRSISYTRDSTLFIKPDLTSNWKGEDFLSSGTLDLWGMNGRGDVCTGNSYYGCSRVGSSSNIINPVTSARLRTMSNFAFRYGRLEVRAKMPRGDWLWPAIWMLPRNWPYGLWPASGEIDILESRGNDDFGTLGNQYGGTTLHWGPFWPYNFFEKTHAEYSANTGSFADDFHVWRLDWTKDNMEFYVDDVLQLTVDPGTSFWDFAGMGPFFDNPWAAGAKMAPFDQKFYLILNVAVGGTNGFFPDGIASKPWSNLSPTAFLDFWNARDEWLPSWKAGEDRISEGAAMQVDYVRVWKMESTEQ
Protein: Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) (Q9BUJ2)
Organism: Homo sapiens (Human)
Function: Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Also plays a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
Subcellular location: Nucleus {ECO:0000269|PubMed:11513728, ECO:0000269|PubMed:12489984, ECO:0000269|PubMed:9733834}.
Interaction partners:
- Nuclear RNA export factor 1
- mRNA export factor RAE1
- Heterogeneous nuclear ribonucleoprotein F
- NTF2-related export protein 1
- Serine/arginine-rich splicing factor 9
- Heterogeneous nuclear ribonucleoprotein H
- Breast cancer type 1 susceptibility protein
- Heterogeneous nuclear ribonucleoprotein H3
- Heterogeneous nuclear ribonucleoprotein M
- Splicing factor 1
Sequence:
MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ
Protein: Capulet, isoform A (Capulet, isoform C) (Q9VPX7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSVAGFEDIVAGPLSQYLTLSAKIGGDVAQHAELVKSAFGSQLQYVTLATQIAQPAQPKQAELLKPTSTQISAIQDFREKHRSSPFFNHLSAISESIPALGWVCVEKTPGPYVKEMNDAGQFYTNRVLKEWKEKDVTHVEWARAWVQTLTELQAYIRQYHTTGLVWSGKGAAPAGGAPPPPPPGGLPPPPPMLDLSALKLDSAGDDRSALFAQINQGADITKGLKKVTGDMQTHKNPSLRTGPAPFKSPAQSGGSKAVAAPSAAQAKAPVFERDGKKWIIEYQKNNTGLLVENAEMNNVVYVFKCEGSTLTVKGKVNNIVFDSCKKCSLLFDSVVASVEFVNCQSVQMQVLGSVPTVSIDKTDGCQMYLSKDSLGVEIVNSKSSEMNILLPDDSGDYTELALPEQYKTTIAGKTLKTVCVDSLG
Protein: Sialoadhesin (J9T303)
Organism: Sus scrofa (Pig)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MDFLLLLLLLASSALAGLASWTVSSPETVQGIKGSCLIIPCTFRFPANVEVPHGITAIWYYDYSGKRLVVSHSRNPKVVENHFQGRALLLGQVEQRTCSLLLKDLQPQDSGSYNFRFEISEGNRWSDVKGTVVTVTEVPSVPTIALPAKLHEGMEVDFNCSTPYVCPTEPVNLQWQGQDPTRSVTSHLQKLEPSGTSHMETLHMALSWQDHGRILSCQVSAAERRMQKEIHLQVQYAPKGVEILFSHSGRNVLPGDLVTLSCQVNSSNPQVSSVQWVKDGTKLKDQKRVLQLRRAAWADAGVYTCQAGNAVGSSVSPPVSLHVFMAEVQVSPVGSILENQTVTLACNTPKEAPSELRYSWYKNHALLEGSHSRTLRLHSVTRADSGFYFCEVQNARGRERSPPVSVVVSHPPLTPDLTAFLETQAGLVGILQCSVVSEPPATLVLSHGGLILASTSGEGDHSPRFSVASAPNSLRLEIQDLGPTDSGEYMCSASSSLGNASSTLDFHANAARLLISPAAEVVEGQAVTLSCRSSLSLMPDTRFSWYLNGALILEGPSSSLLLPAASSTDAGSYHCRAQNSHSTSGPSSPAVLTVLYAPRQPVFTAQLDPDTAGAGAGRQGLLLCRVDSDPPAQLQLLHRGRVVASSLSWGGGCCTCGGCFHRMKVTKAPNLLRVEIRDPVLEDEGVYLCEASSALGNASASATLDAQATVLVITPSHTLQEGIEANLTCNVSREASGPANFSWFRDGALWAQGPLDTVTLLPVARTDAALYACRIVTEAGAGLSTPVALNVLYPPDPPKLSALLDVDQGHTAVFVCTVDSRPLAQLALFRGEHLLAASSALRLPPRGRLQAKASANSLQLEVRDLSLGDSGSYHCEATNILGSANTSLTFQVRGAWVRVSPSPELQEGQAVVLSCQVPIGVLEGTSYRWYRDGQPLQESTSATLRFAAITLSQAGAYHCQAQAPGSATTDLAAPVSLHVTYAPRQATLTTLMDSGLGRLGLLLCRVNSDPPAQLRLLHGSRLVASTLQGVEELAGSSPRLQVATAPNTLRLEIHNAVLEDEGVYTCEATNTLGQTLASAAFDAQAMRVQVWPNATVQEGQLVNLTCLVWTTHLAQLTYTWYRDQQQLPGAAHSILLPNVTVTDAASYRCGILIPGQALRLSRPVALDVLYAPRRLRLTHLLESRGGQLAVVLCTVDSRPAAQLTLSHAGRLLASSTAASVPNTLRLELWEPRPSDEGLYSCSARSPLGQANTSLELRLEGVQVALAPSATVPEGAPVTVTCEDPAARPPTLYVWYHNSRWLQEGSAASLSFPAATRAHAGAYTCQVQDAQGTRISQPAALHILYAPRDAVLSSFWDSRASPMAVVQCTVDSEPPAEMTLSHDGKVLATSHGVHGLAVGTGHVQVARNALQLRVQNVPSRDKDTYVCMDRNSSGSVSTMGQLQPEGVHVVAEPGLDVPEGTALNLSCRLPSGPGHIGNSTFAWFRNGRQLHTESVPTLTFTHVARAQAGLYHCQAELPAGAATSAPVLLRVLYPPKTPTMTVFVEPEGGIQGILDCRVDSEPLASLTLHLGSRLVASSQPQAAPAKPHIRVSASPNALRVDMEELKPSDQGEYVCSASNALGSASAATYFGTRALHRLHLFQHLLWFLGLLASLLFLLLGLGVWYAWRRGNFYKLRMGEYSVEMVSRKETTQMSTDQEEVTGIGDDAGSVNQAAFDPAHLCENTQSVKSTV
Protein: Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4) (P31150)
Organism: Homo sapiens (Human)
Function: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19570034}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:19570034}.
Interaction partners:
- Ras-related protein Rab-1A
- Ras-related protein Rab-8A
- Ras-related protein Rab-1B
- Ras-related protein Rab-10
- Ras-related protein Rab-6A
- Ras-related protein Rab-39B
- Ras-related protein Rab-3A
- Ras-related protein Rab-11B
- Ras-related protein Rab-5C
- Ras-related protein Rab-5A
Sequence:
MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ
Protein: Protein NO VEIN C-terminal domain-containing protein (Q582H4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MADHEDVIRPIRIGPNVLSTEDIDSYVKELLYSAGRKRNAGQNSFKGNVQQKSLTVEYILEKVYGRFFNQSGQSPFPDGLPFALKQIPSIARIAELQLRVTALVQSAVATRPVVTLHELELEVCSAEGVSIFAELGLGDSLTALPFVQHAFNLRSSTGVVAPITSDDFLQFLLFHADAEIMLTSGGDAGDAVRAFAQFYKNGYYTPLQLGIHIQHFSWLLRLLRQETGRTSAFISQIVAENIRAADGRALLYTRVVEALHGSMILREKETSVSHKLFVPFSVRAPMPEAESMGVPLALWNKSGEGPAGGVCLYGVLQTDPISAQPAVPVIVTNAGTEPERSAPHESSAPPSNAVPSAFHGDSSRITNNNDVGTGLACSSAFAYARKRQRRVVADDSTTIVETPSFPKMRVPLEPPPFDVTASKASTVSLPTLSLQDAMSVLRCLVVMQSAHHFSYVPTVHDFTVFKSASNEVVPLFLNGSTSGISSVNSEASNSGTFHVSLEKLLTLLGRTGAPNKLYDLYRSFKNTLYFYNTNDRESSRGVGNDCGENGSPASLMLQCVELGMSDLLFVPVVGTDSLLPLAAARSALSGRVLLSGYRLGADLLDFHPLHIILSPVFDNGGTTYTFAGDTKNRGNRRGNKTAIVIVDSLCLFGCKSFPHSGHLPEPCEKGEHEVQQLARKTLEDCGVITRVPEEWFENDFLAEMLKRQVEDHHNQVCTSTMEDLHMALRMLTLYWWLMGLCFSKTERHLEKVTGLLNSLNDTRWIPYITPGKESNRNMLREDAVRWCTPRELFPSIQCFIASAASELLNFAPRTCVDLIELWKQYAMNYYGAETTARAVREGQFALEFLNRWVPIVRNLVGTSPSLCNELRAALFGMPRSWNAEVALRVLRSLRIGMHVSVGGIRHLVHCIASDVGSRREVALRSLKKEPLLPLPPPHSAIASNEPFIIGELATCDTVHWFSLTECAKAPSSSDCKMGAGGEHFDLEIFDRSICFLGDDLCGFFRELLGVSPVPTVASWVATAQSYRHRVSAGSIINTSLTELFLHALTICCTLQYREIVSVLEKRMGCGSQDRKHRSSPQGVAQNALQELLDRVPANSKGAYIFPLNGKWRSGAEGLFFCGSYYCGFDEVALQAVENGETEGGNSVAALPALKFTHELSHYAVATVLQKMGLTALEDCTEKIVTFSSLNTESSAELHRMIGECVPRVQGFMRAQYPLYYELVDEEVRHRLENFGTTLAKDPVLKEVLRYRGKVYSMVRTVRCTYIPQHHCIYGVDEQFTSSVGAEAVADIFVPRPDAEVRRGLLSALQEWFNCGSLQFYGEEFSCETLSSQVTTEAHETRAPSDDPQWHLSAASVSRFRDHFPLGHEGFSLIGKPLLTAGKSSNGARSANLRVSLWGDGDGYSVRSLPKWSCEFFCSAHEVIRAAVKRIRRGDDESNTGENPDVSEEFDADNDGSAIRNAELGVSIHMGGKHHRRRAKRNPGPMVIYRPEGPLKRYDTHDYSVAAERFVYEKLCNETPTDVEVVWVNEHSELGVPYDILLLRRIVSSPTKKRNIGELTGKEDVLAFIEVKSTCTNTRRDFEMSLREVLFAARFGRAYKVYRVFRASTSAMREMHVEVLEDIITMWHQGKLTLTGEVKVMPTGSG
Protein: Centrosomal protein of 44 kDa (Cep44) (HBV PreS1-transactivated protein 3) (PS1TP3) (Q9C0F1)
Organism: Homo sapiens (Human)
Function: Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall. Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:31974111}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:31974111, ECO:0000269|PubMed:32060285}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:21399614}. Midbody {ECO:0000269|PubMed:21399614}. Note=Localizes to the proximal end of mother and daughter centrioles. {ECO:0000269|PubMed:31974111, ECO:0000269|PubMed:32060285}.
Interaction partners:
- Thymidylate synthase
- Thymidine kinase, cytosolic
- Centrosomal protein of 97 kDa
- Thymidine phosphorylase
Sequence:
MATGDLKRSLRNLEQVLRLLNYPEEVDCVGLIKGDPAASLPIISYSFTSYSPYVTELIMESNVELIAKNDLRFIDAVYKLLRDQFNYKPILTKKQFIQCGFAEWKIQIVCDILNCVMKKHKELSSLQKIPSQQRKKISSGKSEPPLGNEKISAEAVGVDISGRFMTSGKKKAVVIRHLYNEDNVDISEDTLSPITDVNEAVDVSDLNATEIKMPEVKVPEIKAEQQDVNVNPEITALQTMLAECQENLKKLTSIEKRLDCLEQKMKGKVMVDENTWTNLLSRVTLLETEMLLSKKNDEFIEFNEVSEDYASCSDMDLLNPHRKSEVERPASIPLSSGYSTASSDSTPRASTVNYCGLNEISEETTIQKMERMKKMFEETAELLKCPNHYL
Protein: Kinesin-like protein KIF3C (O55165)
Organism: Rattus norvegicus (Rat)
Function: Microtubule-based anterograde translocator for membranous organelles.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}.
Interaction partners:
- Kinesin-associated protein 3
- Kinesin-like protein
- Kinesin light chain 1
- Kinesin light chain
Sequence:
MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQARAVGSTHMNEVSSRSHAIFVITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNTPGGPATQSTAGGGGGGGGTSGSGSSGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKKGMLGKRPRRKSSRRKKAVSAPAGYPEGAVIEAWVAEEEDDNNNNHRPPQPTLEAALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLKREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMLLRDEETMELRGTYSSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHEEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPLVPAGVNNSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPAIFEMEFSHDQEQDPRVLHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPPSTVHASMASAPLHPATVVDHD
Protein: Cbb3-type cytochrome c oxidase subunit (Q9I3G5)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004533, ECO:0000256|PIRNR:PIRNR000006}.
Interaction partners:
- cytochrome-c oxidase
- Cytochrome c oxidase, cbb3-type, CcoO subunit
- Cytochrome c oxidase, cbb3-type, CcoO subunit
- cytochrome-c oxidase
- cytochrome-c oxidase
- Cytochrome c oxidase, cbb3-type, CcoQ subunit
- cytochrome-c oxidase
- Cbb3-type cytochrome c oxidase subunit
- Probable ferredoxin
- Cytochrome c oxidase, cbb3-type, CcoQ subunit
Sequence:
MTTFWSLYITALTLGTLLALTWLIFATRKGQRSSTTDETVGHSYDGIEEYDNPLPKWWFMLFVGTLVFAVGYLALYPGLGTWKGLMPGYQSADEFADKEKGWTGVHQWEKEMAKADEKYGPIFAKFAAMPIEEVAKDPQAVKMGGRLFASNCSICHGSDAKGAYGFPNLTDADWRWGGEPETIKTTIMAGRHAAMPAWGEVIGEEGVKNVAAFVLTQMDGRKLPEGAKADIEAGKQVFATTCVACHGPEGKGTPAMGAPDLTHPGAFIYGSSFAQLQQTIRYGRQGVMPAQQEHLGNDKVHLLAAYVYSLSHGEKSAE
Protein: Protein Turandot A (Q8IN44)
Organism: Drosophila melanogaster (Fruit fly)
Function: A humoral factor that plays a role in stress tolerance; gives increased resistance to the lethal effects of bacterial challenge and stress. Regulated by the JAK/STAT pathway and NF-KB-like Relish pathway in the fat body, upd3 in the hemocytes and Mekk1 in response to septic injury and consequent immune response.
Subcellular location: Secreted {ECO:0000269|PubMed:11369236, ECO:0000269|PubMed:11409894, ECO:0000269|PubMed:12967563}. Note=Secreted from the fat body into the hemolymph. {ECO:0000269|PubMed:11369236, ECO:0000269|PubMed:11409894}.
Interaction partners:
- Protein Turandot M
- Protein Turandot X
Sequence:
MNSSTALMCFALLLISPLCMGYSDEDREADNLRIAEIIKNAQDDDSKINSTQELLDIYRRLYPSLTPEERESIDKFVNEHTDAIIIDGVPIQGGRKARIVGKIVSPGVKGLATGFFEELGSKLAQLFTG
Protein: GPI inositol deacylase (Q38BC3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSRLYIFYKLLLFTALLQLTVVCPSIHTAKAEARESKSLGSSDTWGCVLCTAVVATVSQLGQLHQIPAKDALGLFCSFFRSAEAVLCKTASLILLEGALQLIDEGRTPDKVCQIMKYCDTEECILFPPDKNDTLPLHKLRSAYRLDGRKLVDACRTFPTLCRPLFEDSAHDKDGDRFSTYPTKRGTDWRGRDCDDDDARVYPGRNSTDSQRDENCNGIYGVEESSKKTYEELWCSNSSPMGVIAVGDSATADFGIPLGYVSILDLSSEAVANIIPVLDNEIDWPMLSGLTGFANSTRYEPDVDGPMASVYSKLVELNRCNHRDYQNLGHNGARSGSILSILDSVARNRSESVKPAYVFFSMVGNDVCPRPQDAPTPLDYYHSLSEAVKKADSFLPPGSHVLIVSLVDARAAIGSIVNRIHPIGTLNSDVTYGNLYDYLNCLQVSPCWGWLNSNESVRNETWERASAMNAMISRVVDESTDLENIKVHALGDVIGEVVSSFEGPLWKLVNPVDGFHPSQIATALMGARVFAKMQDLGILPTENPFNGDIQRRFGDQGGY
Protein: Omega-theraphotoxin-Gr1a (Omega-TRTX-Gr1a) (Omega-grammotoxin SIA) (Omega-GTX SIA) (Omega-GrTx SIA) (Omega-GsTx SIA) (P60590)
Organism: Grammostola rosea (Chilean rose tarantula) (Grammostola spatulata)
Function: Inhibits P/Q- (Cav2.1/CACNA1A) and N-type (Cav2.2/CACNA1B) voltage-gated calcium channel by modifying voltage-dependent gating. It selectively and reversibly blocks the calcium channels coupled to glutamate release. Also inhibits potassium channels (Kv2.1/KCNB1) with lower affinity. Has also been shown to weakly inhibit Kv11.1/KCNH2/ERG1, Kv1.2/KCNA2, Kv1.3/KCNA3, Nav1.5/SCN5A, Nav1.7/SCN9A and TRPV1.
Subcellular location: Secreted {ECO:0000269|PubMed:8394998}.
Interaction partners:
Sequence:
MKAQIFVVVLGLAALSVLCYGSEADESALHEEIFQLLAASDEVPKPQERDCVRFWGKCSQTSDCCPHLACKSKWPRNICVWDGSVGK
Protein: PTS system N,N'-diacetylchitobiose-specific EIIB component (EIIB-Chb) (IVcel) (N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component) (EC 2.7.1.196) (P69795)
Organism: Escherichia coli (strain K12)
Function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2). Also able to use N,N',N''-triacetyl chitotriose (GlcNAc3).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- PTS system N,N'-diacetylchitobiose-specific EIIA component
- PTS system N,N'-diacetylchitobiose-specific EIIC component
- 6-phospho-beta-glucosidase
- 6-phospho-beta-glucosidase AscB
- 6-phospho-beta-glucosidase BglA
- HTH-type transcriptional regulator ChbR
- 6-phospho-beta-glucosidase BglB
- Chitooligosaccharide deacetylase ChbG
- Phosphocarrier protein HPr
- Cryptic beta-glucoside bgl operon antiterminator
Sequence:
MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLAGEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKKAAAN
Protein: Acetylcholine receptor subunit alpha (P02710)
Organism: Tetronarce californica (Pacific electric ray) (Torpedo californica)
Function: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:P02708}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P02708}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MILCSYWHVGLVLLLFSCCGLVLGSEHETRLVANLLENYNKVIRPVEHHTHFVDITVGLQLIQLISVDEVNQIVETNVRLRQQWIDVRLRWNPADYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIVHMTKLLLDYTGKIMWTPPAIFKSYCEIIVTHFPFDQQNCTMKLGIWTYDGTKVSISPESDRPDLSTFMESGEWVMKDYRGWKHWVYYTCCPDTPYLDITYHFIMQRIPLYFVVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMIFVISSIIITVVVINTHHRSPSTHTMPQWVRKIFIDTIPNVMFFSTMKRASKEKQENKIFADDIDISDISGKQVTGEVIFQTPLIKNPDVKSAIEGVKYIAEHMKSDEESSNAAEEWKYVAMVIDHILLCVFMLICIIGTVSVFAGRLIELSQEG
Protein: Golgin subfamily A member 2 (Golgin A2) (cis-Golgi matrix protein GM130) (A1IH00)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:Q08379}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q08379}; Cytoplasmic side {ECO:0000250|UniProtKB:Q08379}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q08379}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q08379}; Cytoplasmic side {ECO:0000250|UniProtKB:Q08379}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q08379}. Note=Associates with the mitotic spindle during mitosis. {ECO:0000250|UniProtKB:Q08379, ECO:0000250|UniProtKB:Q62839}.
Interaction partners:
- Golgi SNAP receptor complex member 1
- Golgi reassembly-stacking protein 1a.
- Syntaxin-5
- General vesicular transport factor p115
- Syntaxin 5A,-like.
- Golgin B1.
- Serine/threonine-protein kinase PLK
- Golgi SNAP receptor complex member 2
- Thyroid hormone receptor interactor 11.
- Sec1 family domain-containing 2
Sequence:
MADQNRQIKLAAAKKKLKEFQQKTIPSTGSAGPKKKRKVKGDQTDAPADRRSPENERVDVSQELEEAGAEHVSNPASAINTDNSAPQNYPADANGDEHPLENNRPLSSTESLRQLSQQLNGLLSESSTHINGDSDPPAVNEKELETRNQELSAALDSSALTNTQLTSKLETLTKQSQELSDQLQKERKEFEQKFTKEQGAMREQLQVHIQTIGILVSEKSELQTALSYTQQAARQKAAEAEDLSSRLQASKQRVSELERTLSSVSTQQKQHERHNKELEKERDSLRLEIIRFNNVSEESRQQSSELSEQLKLRVNENSALKLELEDLRKRLEMADVMLQQFSSQSGPPSEHQQLQLLLEEKHQLENHATQLMESVAQLQAERDQYAVQMQEDGRVWKDKTEQLLSQVRLMSEERDSTAAQILELQERIMELENTAAVMSTEQEPQASSQLSGPSETELALQETLRSLQEERDALSLQFQAQVRDNEQLSRLVQEQEVKLQELERQAERASEDAQDRLRILEDVQSDKATISRALTQNRELKDQLAELQNGFVKLTNENMELTSALQSEQHVKKEIARKMGQLQEDLHNAKEQLLESSSELTSVQEQRDQYLAHLQQYSAGYQQLLAEREHLQKQFLQQTQLMDRLQHDEVQGKVQLEQSHMQLQEVQEKLSRLVRDNEELKTEVQELLNGSIMNTSHRDEGDGLESQTLPESFQKSQIAIPEDFESREEMKEFIHSVLSRVEAERDEMSRRLEEERRIHQDTRQQLTALSHDHHHHHHHEPHSTCAETDGSEGVPVEVHEALRVAMEKLQERFTKLMQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQNQRAIMKQKHVEKEQYINMLAKDKEEMKTKLAELQDLVMRLVGERNEWYSRYMSAVGNRDLLNSNAEQIHPAERRMEISGVDAPAVLDMSTAMDVSSSPQSSTAEIQSQSSERPAADPISSPSLRPQEDGTARQIMQLLQEIQNPQSRPAPFLGENPCIPFFYRPDEHDEVKILVV
Protein: Olfactory receptor (Q8VF05)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
Interaction partners:
- Receptor-transporting protein 2
- Guanine nucleotide-binding protein G
- Vomeronasal type-1 receptor
- Receptor-transporting protein 1
Sequence:
MEKWNQSSSDFILLGLLPQNQTGLLLMMLIILVFFLALFGNSAMIHLIRVDPRLHTPMYFLLSQLSLMDLMYISTTVPKMAFNFLSGQKNISFLGCGVQSFFFLTMAGSEGLLLASMAYDRFVAICHPLHYPIRMSKIMCLKMIIGSWILGSINSLAHSIYALHIPYCHSRSINHFFCDVPAMLPLACMDTWVYEYMVFVSTSLFLLLPFLGITASYGRVLFAVFHMRSKEGKKKAFTTCSTHLTVVTFYYAPFVYTYLRPRSLRSPTEDKILTVFYTILTPMLNPIIYSLRNKEVLGAMTRVLGTFSSMKP
Protein: Probable ribosome biogenesis protein RLP24 (Large ribosomal subunit protein eL24x) (O22165)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles.
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- AT5g04600/T32M21_200
- Pescadillo homolog
- Ribosome assembly factor mrt4
- Protein MAK16 homolog
- Nuclear/nucleolar GTPase 2
- Expressed protein
- 60S ribosome subunit biogenesis protein NIP7 homolog
- 60S ribosomal export protein NMD3
- Probable rRNA-processing protein EBP2 homolog
- Ribosome production factor 2 homolog
Sequence:
MRLEKCWFCSSTIYPGHGIQFVRNDAKIFRFCRSKCHKNFKMKRNPRKVKWTKAFRAAHGKDMTKDTTFEFEKKRNRPERYDRNVTENTLMAIKKIAKIRTAREAKHIENRLKPNKQKKLNDDMKELDQNIHMVQAPGAQKIKVDVSEKKSVQNEAMEE
Protein: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8) (O35077)
Organism: Rattus norvegicus (Rat)
Function: Has glycerol-3-phosphate dehydrogenase activity.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P21695}.
Interaction partners:
- Dihydroxyacetone phosphate acyltransferase
- Glycerol-3-phosphate acyltransferase 1, mitochondrial
- Glycerol-3-phosphate acyltransferase 2, mitochondrial
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- Glycerol-3-phosphate acyltransferase 3
- 1-acylglycerol-3-phosphate O-acyltransferase 6
- Glycerol-3-phosphate dehydrogenase [NAD
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
- 1-acylglycerol-3-phosphate O-acyltransferase 3
Sequence:
MAGKKVCIVGSGNWGSAIAKIVGSNASQLAHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGIDEGPNGLKLISEVIGESLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGSVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFICCLQNHPEHM
Protein: Interferon antagonist OPG040 (32.5 kDa protein) (Host range protein 1) (P04297)
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Function: Inhibits antiviral activity induced by type I interferons. Does not block signal transduction of IFN, but is important to counter the host antiviral state induced by a pre-treatment with IFN. Plays a role in the inhibition of host NF-kappa-B activation by preventing the acetylation of the RELA/p65 subunit of NF-kappaB.
Subcellular location: Host cytoplasm {ECO:0000269|PubMed:27503790}. Host nucleus {ECO:0000269|PubMed:27503790}.
Interaction partners:
Sequence:
MDLSRINTWKSKQLKSFLSSKDAFKADVHGHSALYYAIADNNVRLVCTLLNAGALKNLLENEFPLHQAATLEDTKIVKILLFSGLDDSQFDDKGNTALYYAVDSGNMQTVKLFVKKNWRLMFYGKTGWKTSFYHAVMLNDVSIVSYFLSEIPSTFDLAILLSCIHITIKNGHVDMMILLLDYMTSTNTNNSLLFIPDIKLAIDNKDIEMLQALFKYDINIYSANLENVLLDDAEIAKMIIEKHVEYKSDSYTKDLDIVKNNKLDEIISKNKELRLMYVNCVKKN
Protein: Nuclear pore complex-interacting protein family member A7 (E9PJI5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFCCLGYEWLSGGCTTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHREEERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECVLYPLPPSADDNLKTPPECLLTPLPPSALPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSADDNLKTPPECVCSLPFHPQRMIISRN