wanglab/gogpt-training-data huggingface dataset:
Protein: Head completion nuclease (EC 3.1.-.-) (Head completion protein Gp50) (Protein Gp4) (P15075)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: During phage morphogenesis, plays an essential role in the head-tail joining step. The associated nuclease activity is essential for morphogenesis, possibly by cleaving packaged DNA to enable the joining of heads to tails. Displays both exo- and endonuclease activity.
Interaction partners:
Sequence:
MAYSGKWVPKNISKYRGDPKKITYRSNWEKFFFEWLDKNPEIIAWGSETAVIPYFCNAEGKKRRYFMDIWMKDSSGQEFFIEIKPKKETQPPVKPAHLTTAAKKRFMNEIYTWSVNTDKWKAAQSLAEKRGIKFRILTEDGLRALGFKGA
Protein: Protein disulfide-isomerase A2 (EC 5.3.4.1) (Pancreas-specific protein disulfide isomerase) (PDIp) (Q13087)
Organism: Homo sapiens (Human)
Function: Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
Interaction partners:
- Endoplasmic reticulum chaperone BiP
- ERO1-like protein beta
- ERO1-like protein alpha
- Endoplasmin
- Thioredoxin
- DnaJ homolog subfamily B member 11
Sequence:
MSRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVAADNEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL
Protein: LysM domain protein (O51302)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Interaction partners:
- Tetratricopeptide repeat domain protein
- Uncharacterized protein
- Lipoprotein
- Basic membrane protein D
- M23 peptidase domain protein
- Basic membrane protein
- N-acetylmuramoyl-L-alanine amidase, putative
- Borrelia P83/P100 antigen
- DNA topoisomerase 1
- Membrane protein, putative
Sequence:
MNIKNKLISLLIVVAISFIACKTPPESRESKNAKIAQPDNKNFQLRDIKDIKNELIRERGHLFYSKEFNEAERLEEAMKQSFSKKKAIEGNEIALKVLERYKTIIRETREKKEKTNYLKENIEKYLNDAEANEAYIWIPLEIDEVNNLYFEATRKYKNYDLDNALDMYSKAFNRAQQAAKNAKEAKALKETDERMYKQLKALEAASNLPIYSNNKLIKPSPWNGRAFIKERNSHLNLLNTNKDTYLLGEAEISIPIVLAYEEKVEIAKNSKPQEQFKTLELIERSRTLWEKGVEAKNVKNFRLANELFLESARYLEAYQSNASSELYVIKIGNTLWGISKKLYNDPYLWPKIWFANRQKIQNPDLIHSNWKIIIPAK
Protein: Laforin, isoform 9 (B3EWF7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:22036712}.
Interaction partners:
Sequence:
MHPKEGAEQHVFSPVPGAPTPPPNRCGRLVLGPRLPAAGTPGPGIRAAAARHALPLWGGGATRRGRRPAGAAGGGVAARAGALGAARCRPPEAGRHRGGRRGPGPAGAGPVARGGGAGGRGGGAGRGGAGPRGHVLVQVPEAGAGRRALLGRYCQQTPAPGAERELRPAPPTGASASGRPRRPRRRASRAFCPRPCALPGRPGLTLLCRPRCRRQPRLRLPTDSLDPYSAPGRLPAHSVACPSDLVSAHPVLSFFPTAPASRASALRLPPGAPFALRVPLDLRVPPFAGPLAARPRAADGFNSPTPPWLGFVSSFSCSNSLKKTQNDPTNETSVFANPRQQCAT
Protein: SET domain-containing protein (Q581V5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKFVWLDTKPQRYICANRSTYRDIWPRLASMRVPAAYSLTRWVARKGGAFHCALRLHPHRNRGCCLVAQRPIKSGAALISVPVSLSISAFTQGSDDERNIAARWGPLEELAGTLTRELHNPSSFHRLYLEFLHDVYNSDATDQFAVNEPLQNELDAMYMGNALHVKGVPNAPFISKSKLVTASQRADWIRIDYLRRRMEQSLPHFASKSTSWGLSMALARALRDDDGGLTMYPLIDFSLHDYEPNAMIHLTHPECHSEGSIGGRWYDKTQPCAHLVARQTIPAGSAVTIAYSTRAAASQEDAEYWKMKWGFVPDREGRARTVETDGERRVPTGI
Protein: Auxin-responsive protein SAUR26 (Protein SMALL AUXIN UP RNA 26) (Q6NMM4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion (By similarity). Functions as positive effectors of cell expansion through modulation of auxin transport (By similarity). Involved in thermo-responsiveness of plant architecture. Enhances plasma membrane H(+)-ATPase. Probably involved in light intensity mediated root development.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9FJG1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9FJG1}.
Interaction partners:
- Lysine-specific demethylase JMJ13
- Cyclin-dependent protein kinase inhibitor SMR8
- Lysine-specific demethylase JMJ32
- Classical arabinogalactan protein 7
Sequence:
MALVRSLFSAKKILGGSLVKTSKAPPKGFLAVYVGESQKKQRHFVPVSYLNQPLFQDLLSKCEEEFGFDHPMGGLTIPCPVDTFISITSQLQG
Protein: Uncharacterized protein (Q57YS9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- GTP-binding protein, putative
- Vacuolar protein sorting-associated protein 45, putative
Sequence:
MKGLSRLDVFPKFDTRFEQDARQRTALGGVLSMASILIITFLVVGEIRYFLSTVEQHEMYVDPHIGGIMHMKVNITFPRVPCDLMTADAIDAFGEYVENVVTDTAKVRVDSSTLKPLGKARQLVDLKKQPTNGNETGNENCPTCYGAEKNPGECCHTCDDVRRAFAERQWEFHEDDVSIAQCAHERLKVAADSASAEGCNLHASFSVPRVTGNIHFVPGRMFNFFGQHLHSFKGETIRKLNLSHIVHALEFGERFPGQNNPMDGMVNARGVKDPSEPLIGRFTYFVKVVPTLYQVVSMANTGNLVESNQYSVTHHFTPSWAAPKEGETDNPNSDPLVVPGVFISYDISPIRVSVTRTHPYPSIVHLVLQLCAVGGGVYTVTGLIDSLFFHGIKRVQEKINRGKQF
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (Q4GYH2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Heat shock protein, mitochondrial, putative
- Heat shock protein 83
- Lipophosphoglycan biosynthetic protein, putative
- CS domain-containing protein
- CS domain-containing protein
Sequence:
MGCSTSKGDPLRTNKGAGDGAGSLRNPPGGRWSQTDYPDVGNQRHLPQCHFCKRFIAEKEYNAHTVMCDEREMTCWNSWCRQMVKQGMLSKHLEECAKNQRALCYKCGTEVLASDLQVHRDTCQPKKCSACGELCITRILSWCPHNFGRIGATQGPFATEALSKKYLSGGGRPKGASSVHNNSPPHVNFNVARMQLLWRWIKTKSIIEETLFRVMSREMDLKKEGFAIFKALDKVNESHVLAPKRSRSILQSPVVAPAVSSHYFPTRSSDPITLDVVSRLMKDLSEHILPPYPAVWRVFTDAMCYLNTMPNVVLLSPPLGARVVNGRVNQGSKVVVVGDLHGQLADLLHILKECGMPNDSTYYIFNGDFVDRGPNGVEVLLIIFSLMLACPKFVTLNRGNHECDYMNEEYGFDVEVSTKYDRNVFRLIQRCFCAMPLATIIGRKVFVVHGGVPRRKGVRIEDISRIQRFRQIPMPDYSQPEEDEIFQDLLWSDPVEDLQGWRESHRGAGVEFGPDLTHEFLQSNGLELIIRSHCDCERGYEEFHDGKLVTVFSASNYNGPDTNYGSVAVFIGDNPEPSFSVHKVLEDDLEAHHHVDLGETQTGGLGMTLTSLSMLHLVRPAIRRRTKDEVLRVLRERVYQRRHRLMAYFNKLDRTRKGSVWKIEWVEAMRNVLNTDLPWFFLRGYLAAEDDDGRIWYSLFLVKFHNKLQSLWLNEWISSARDRLIQQQRANHRSQYVANSFNREQVGYNEFCSVMRAIDYTMSDGHLFQLFVHFDERGVGFIDGRKFVHMLSEANTSHPGADPLRWDLEAMEQLQSVVIQGRGQLQYLFKVSTKDCVLTKESFMWGLEQLGRGMRRQLTQQQKERIYEYLLERAPNGSVLFGQFLFMTTVFDNCTMSTSSAIDLADINLVAYCLRNCSFSSFVRD
Protein: Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes) (Phosphoprotein enriched in diabetes) (PED) (Q15121)
Organism: Homo sapiens (Human)
Function: Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
Subcellular location: Cytoplasm. Note=Associated with microtubules.
Interaction partners:
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 3
- FAS-associated death domain protein
- Ribosomal protein S6 kinase alpha-3
- Phospholipase D1
- Caspase-8
Sequence:
MAEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIFEISRRPDLLTMVVDYRTRVLKISEEDELDTKLTRIPSAKKYKDIIRQPSEEEIIKLAPPPKKA
Protein: Cationic amino acid transporter 4, vacuolar (Q8W4K3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Permease involved in the transport of the cationic amino acids.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:17151019}; Multi-pass membrane protein {ECO:0000269|PubMed:17151019}.
Interaction partners:
- Probable polyamine transporter At1g31820
- WAT1-related protein At3g28100
- WAT1-related protein At3g28070
- WAT1-related protein At4g15540
- WAT1-related protein At3g28130
- WAT1-related protein At3g28050
- WAT1-related protein At3g28080
- Mitochondrial arginine transporter BAC1
- Monothiol glutaredoxin-S10
- Amino acid permease 1
Sequence:
MNSLVRRKQVDSVHLIKNDGPHQLAKKLSAVDLVAIGVGTTIGAGVYILVGTVAREHTGPALAVSFFIAGVAAALSACCYAELASRCPSAGSAYHYAYICLGEGIAWLVGWALVLDYTIGGSAIARGITPNLASFFGGLDNLPVFLARQTIPGVGIVVDPCAALLIMIVTILLCFGIKESSTVQAIVTSVNVCTLVFIIVVGGYLACKTGWVGYDLPSGYFPFGLNGILAGSAVVFFSYIGFDTVTSTAEEVKNPQRDLPLGIGIALLICCILYMLLSVVIVGLVPYYSLNPDTPISSAFGDSGMQWAAYILTTGAITALCASLLGSLLAQPRIFMAMARDGLLPAFFSEISPRTQVPVKSTIAIGVLAAALAFFMDVAQLSEMVSVGTLMAFTAVAVCVLVLRYVPPDGVPLSSSSQTLSDTDESRAETENFLVDAIESSDSPLLGNETARDEKYFGKRRKIAAWSIALVCIGVLGLASAASAERLPSFPRFTICGVSAVILLGSLITLGYIDEDEERHNFGHKGGFLCPFVPYLPVLCILINTYLIINIGAGTWIRVLIWLLIGSMIYIFYGRSHSLLNNAVYVPTMTCTRKTTDHLA
Protein: Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9) (F1QWZ4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/eng.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q9UK05}.
Interaction partners:
- Receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- Receptor protein serine/threonine kinase
- Receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- receptor protein serine/threonine kinase
- Mothers against decapentaplegic homolog.
- Serine/threonine-protein kinase receptor
- receptor protein serine/threonine kinase
- Mothers against decapentaplegic homolog 5
Sequence:
MWRVGHLLLLMSIVFRITEEKSLGDAGSLEDSMFIQEQKLVEDDDLNKVESFLGFMKEDFLRKLNLSGVPQEHRKVQPPQFMIELYNRYASDKNSIPRSDVIRSFVVQDVIYSIRQGNKTQHRLLFNVSIPNHEEITSVQLRLFTLWHRHKPACDDLFTSINVYDVEYEQNAKILHLLDGRDVRESINTWEAFDVTGAVRIWHESRRGAGEIQVEVQHSCDSFDISLSLEDNSSAVVIVFSDDLGNRKEESMRKVKEMLVREQQQVGNQAPVSNRHRRRKRKAKNNYCRRTSLKVNFKDIGWDKWIVAPPEYDAYECKGVCYFPLTDDVSPSRHAVIQTLVNLSNPKKANMACCVPTKLDPIAVMYQEKGVITVRHLYEEMKVAKCGCR
Protein: DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon 58kD subunit) (DNA polymerase epsilon subunit) (Q9VRQ7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Has a role in the entrance and progression through S phase. Has a role in endoreplication. Essential for viability and tissue development.
Subcellular location: Nucleus {ECO:0000255|PIRNR:PIRNR000799}.
Interaction partners:
- DNA polymerase epsilon catalytic subunit 1
- DNA polymerase epsilon subunit 3
- DNA replication licensing factor Mcm5
- CDC45L
- DNA replication licensing factor Mcm2
- DNA replication licensing factor Mcm3
- DNA polymerase epsilon subunit 4
- DNA replication licensing factor Mcm6
- DNA replication complex GINS protein PSF1
- DNA replication licensing factor MCM4
Sequence:
MDVDLLPLRKRITNTFKLCGFLIRSENSSYLAEQLLPFDAAERDKWLTVITENLQSQKLLTPHVERAALEKAINELNRVGLDEGETVFALIDAFTVPRFRYNQRIKKFELDTQPRQLLTAPRMKSDYMQQRYAMLLQKTLRHDLFAPAVIQDGVGAEAQAKKFKLQFAENLLATSAMKEAVVLGLLTQLKEGKFYVEDPTGCVQLDLTGARFHAGFFCEGCFVLAEGNYNNGVLKVDGLGFPPAEPANSSRAFFGTANTWGGESAKLLKYSAGLQELERTNTETTIVFLSDVRLDLPVVMEKLRQLFVGYDSCPPQAIVLMGPFTASTRNHHELRHHLDALGGLAAGCEQLKKQTDLILVPSSEDPTAPNILPRAPIPECLAAGLLKAWPRTQLATNPCRLQYCTQQIVVCRLDLMAKFCRNTLHFPEDTSQIEQHFARTIVCQGHLVPIHPIAMPVHWDYDPALWLYPLPDLIVMGDSCQSFSSSQHGCTVLNTGSFVKSKFAFKVYIPATRTIEDSEIPDELE
Protein: Telomere replication protein EST3 (Ever shorter telomeres protein 3) (Q03096)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.
Subcellular location: Nucleus {ECO:0000305}. Chromosome, telomere {ECO:0000305}.
Interaction partners:
- Telomere elongation protein EST1
- Telomerase reverse transcriptase
- Cell division control protein 13
- Ribonucleases P/MRP protein subunit POP6
- Ribonucleases P/MRP protein subunit POP1
- ATP-dependent DNA helicase II subunit 2
- ATP-dependent DNA helicase II subunit 1
- Protein STN1
- Ribonucleases P/MRP protein subunit POP7
- Protein RIF2
Sequence:
MPKVILESHSKPTDSVFLQPWIKALIEDNSEHDQYHPSGHVIPSLTKQDLALPHMSPTILTNPCHFAKITKFYNVCDYKVYASIRDSSHQILVEFSQECVSNFERTHNCRITSETTNCLMIIGDADLVYVTNSRAMSHFKICLSNISSKEIVPVLNVNQATIFDIDQVGSLSTFPFVYKYL
Protein: AT10158p (Mrityu, isoform A) (Mrityu, isoform B) (Q0E8K5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Glycerol-3-phosphate acyltransferase 4, isoform D
- BcDNA.GH07066
- glycerol kinase
- glycerol kinase
- Phospholipid/glycerol acyltransferase domain-containing protein
- LD24679p
- glycerol kinase
Sequence:
MSNTPSLNSSSSNISSKAPLAQKQDTYSSDSSEEVLETAEERRRRILKERSRLNRPQHNMSGGGAVPKHDIKSPCGASPSCQATGSGMGRLPLPPERITMLVDGVRFTVEQSLLTAHPTTMLGTMFGSGFQFAHTNERGEYDVADGISHLVFRAILEYYKSGVIRCPPTVSVPELKEACDYLLIPFDATTVRCQNLRGLLHELSNEGARQQFELFLEDLILPLMVASAQRGDRECHVVVLLEDDMVEWDEEFPPQMGEEYCQTVHSTAMHRFFKYIENRDVAKQVMKDRGLKKIRCGIEGYPTHKEKIRRRPGGRAEVIYSYVQRPFIHMSWEKEEAKSRHVDFQCVKSKSVTNLAEANADPPLELDASGNPIPPIAVANPHPNNAELAAGMAVAPAAIGVAGPAVVVAVDEAAGGVVMLNELDQAAIAVAVGIVDENM
Protein: Serpin 28Da (Q0E8V6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Serpin 28B, isoform A
- Serpin 85F
- Uncharacterized protein, isoform E
- MD-2-related lipid-recognition domain-containing protein
- Serpin 38F, isoform A
- Prolyl 4-hydroxylase alpha subunit domain-containing protein
Sequence:
MKYLCWILVTTSVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGRFKMRTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQIVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDDDNIYFRGRVVDPLKKSNPIDRITI
Protein: Bone-derived growth factor (Q13876)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
AEDEEVQQRLRAAPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHSIAFAPTWKALAEDVKRWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVARVVNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLGGPEKVCGSSGQVFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSCGSSSTSRLCRQLGSKCRPLTGSTQGQGGPPSHPRLAALLLRLPRLRKPLRADAAASMHRVGSPNAAVLWLWSSHNRVNARLQVPPARTPSSPRCSGHPVNFVLPATMNAWMCPCGTWKPPSTSSRPTSPQATSSWTSLQLGQLPEGCAECAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEGPEASRPPKLHPGLRAAPGQEPPEHMADVQRNEQDEPLGQWHLRSETQGLHCWLSPGLRRTASGALWRSGAWAAAPSSWSTSLRPAGGPSWTGRGQWLQVLGGGFSYLDISLCVGLYPCPSWACWHVHLLPGQDKALNRMLATLQPEPPGEEAGEGAAISRHLKPPDPIPSPPTPCSLSGLEVWEIQENELLQ
Protein: Telethonin (Titin cap protein) (O15273)
Organism: Homo sapiens (Human)
Function: Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk.
Subcellular location: Cytoplasm, myofibril, sarcomere {ECO:0000269|PubMed:16713295}.
Interaction partners:
- Titin
- Cysteine and glycine-rich protein 3
- Myozenin-2
- Myozenin-1
- Myosin-7
- Alpha-actinin-2
- E3 ubiquitin-protein ligase TRIM63
- Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
- Ankyrin repeat domain-containing protein 2
- Myosin light chain 3
Sequence:
MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG
Protein: Ring finger protein 6 isoform 1 (A0A024RDP2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNLLGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEVPRESSHEDSLLEWLNTFRRTGNATRSGQNGNQTWRAVSRTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRDHTANRQQRSTSPVARRTRSQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIGGAAGIPRANASRTNFSSHTNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEPIRLRSTSNSRSRSPIQRQSGTVYHNSQRESRPVQQTTRRSVRRRGRTRVFLEQDRERERRGTAYTPFSNSRLVSRITVEEGEESSRSSTAVRRHPTITLDLQVRRIRPGENRDRDSIANRTRSRVGLAENTVTIESNSGGFRRTISRLERSGIRTYVSTITVPLRRISENELVEPSSVALRSILRQIMTGFGELSSLMEADSESELQRNGQHLPDMHSELSNLGTDNNRSQHREGSSQDRQAQGDSTEMHGENETTQPHTRNSDSRGGRQLRNPNNLVETGTLPILRLAHFFLLNESDDDDRIRGLTKEQIDNLSTRHYEHNSIDSELGKICSVCISDYVTGNKLRQLPCMHEFHIHCIDRWLSENCTCPICRQPVLGSNIANNG
Protein: Transcriptional activator protein EsaR (P54293)
Organism: Pantoea stewartii subsp. stewartii (Erwinia stewartii)
Function: Functions as a potential OhlL-responsive transcriptional regulator.
Interaction partners:
Sequence:
MFSFFLENQTITDTLQTYIQRKLSPLGSPDYAYTVVSKKNPSNVLIISSYPDEWIRLYRANNFQLTDPVILTAFKRTSPFAWDENITLMSDLRFTKIFSLSKQYNIVNGFTYVLHDHMNNLALLSVIIKGNDQTALEQRLAAEQGTMQMLLIDFNEQMYRLAGTEGERAPALNQSADKTIFSSRENEVLYWASMGKTYAEIAAITGISVSTVKFHIKNVVVKLGVSNARQAIRLGVELDLIRPAASAAR
Protein: Exocyst complex component 2 (Exocyst complex component Sec5) (Q22706)
Organism: Caenorhabditis elegans
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Interaction partners:
- Exocyst complex component 1
- Exocyst complex component 5
- Exocyst complex component 4
- Exocyst complex component 3
- Exocyst complex component 6
- Exocyst component Exo84 C-terminal domain-containing protein
- Exocyst complex component 7
- Rab8
- RNA polymerase II-associated protein 3
- small monomeric GTPase
Sequence:
MEENAQARERLPPTVTGLSPTEGVPGTQITIRGENLGNDQSDVIMLFICGIDSLWSMKWKSPSKIIARVGAASRGPGEVRIATKSGGKGSSNVKFRVFITQIGPLEESAVWVDETRTVPGREAIRSVPQIQDERDALGLLPSQKRMDQVLLSRDFPDCSGNLRMENFSPQWYLLENHADATIEDLRIAIKNMELSKQNEAKRSEEMHKANLYSLINCVDTLANLHQALEKGENADHFAALKNISKLIKDSKSKAENVFADVLKRKDDADATRNALGVIVRFKFIFFLSSKIEDSMKKGEYITILNDYTRAKSLYADTDVPLFRELMTEIDEKMQVFKEEMKRKLIDTPVSYEEQSKLIKYLKILDPESDPTWDCITSYYVWLEKSLWDMQTQFLEKAKLEDLENQQRINSQNHLITKTNELQNFVTTLVELLLSKLPSFWKLANTYHNSTASPDAIQRLEDINQMLTNIINVSSWLILNALVPKALPDMVLKQYGDQFAKWPTVPADISRSNLQLSLKTTRSLISSLLENQFSLTHVQPLVELCMTARLKLLSDFVDCGVERVALLAHRINWKQDILDRAQQTKTILPDYYENEICECLTRTRDALSISGYPGEACLFSRERFRDTIIDLFVHLITSIKICFDRLFIRQRPQQLAQEPGQKKGNNEITTKKLLIAVGDIEFIIAKTLNNVGKKMQECGVKHVDQIQEKSRAKLSAFRTKMINDCIAMMSSAFEPLIASATYEYLPDDDDISDYAKEMILCSVLQQAELELYAPQLAIECLQQTVSNALDALLLHFSRLNQDTSPLIVTQIVIDLTGLEEALSTYATLAIRVQINTYRAGLVGRFDNQRLQQCLKNMRTTMRMALQSLEQHAENLGDDSHNTSNI
Protein: Big bang, isoform I (PDZ domain-containing protein BBG-LP43) (Q9VUE7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLRINRYRDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEADPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA
Protein: Glycerophosphocholine cholinephosphodiesterase (Q22129)
Organism: Caenorhabditis elegans
Interaction partners:
- Uncharacterized protein
- Phospholipase A2
- Phospholipase A2
- Intracellular phospholipase A2
- phospholipase A2
- Uncharacterized protein
- Protein linkin
- F-box protein dre-1
Sequence:
MNLVLILLGLVLGSAARDPIGQNLIVILADGYGATLLNNTKPDATFGIRHLATNGVQVDYVTPSFPTHTWPQWMSLSTGLYTENHGFTADYMWDRKTNFTFERGTGPNDTEDVWWDDAKAPLWYTAGKAGVDVHCYWFAHCHRAFYDMVVQVPEKRWANLDDQHQTDNLRDIFPEIANRISKYQVYKQQMFLIRYANIGNAQKEHGPESDEVEQEVARFDLYINELQQLLEDRGLFSSTNLVVMSDHGYTPLQKEEQFFMEQCLPDYSLVKKVVNSHSMIMVFTNPEDEGTVHYEFSVCEVWSPMGDYDENDTPFVKTYRMSELPDDLHWKNSRFMSGVVLITKPGTSVVTKELPTVPHSGDPTIDAKQASGWEPYHDDMKGIFVARGPAFRENERFGPIEIVDVYQMLLNILSIEPAHPHNGTWTNVENMLSEGWENRGPVDSSAFRSSGTLLCSIFVLLHFFF
Protein: Large subunit GTPase 1 (EC 3.6.1.-) (Q10190)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: GTPase required for the nuclear export of the 60S ribosomal subunit. Acts by mediating the release of nmd3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- 60S ribosomal export protein nmd3
- Eukaryotic translation initiation factor 6
- Large ribosomal subunit protein eL27A
- Large ribosomal subunit protein eL27B
- Probable nucleolar GTP-binding protein 1
- Probable metalloprotease arx1
- Cytoplasmic 60S subunit biogenesis factor SPCC550.15c
- Tyrosine-protein phosphatase yvh1
- Protein sda1
- AdoMet-dependent rRNA methyltransferase spb1
Sequence:
MVLPKSKNQIGLGRAIQSDFTKNRRNRKGGLKHIVDSDPKAHRAALRSVTHETDLDEFLNTAELGEVEFIAEKQNVTVIQNPEQNPFLLSKEEAARSKQKQEKNKDRLTIPRRPHWDQTTTAVELDRMERESFLNWRRNLAQLQDVEGFIVTPFERNLEIWRQLWRVIERSDVVVQIVDARNPLFFRSAHLEQYVKEVGPSKKNFLLVNKADMLTEEQRNYWSSYFNENNIPFLFFSARMAAEANERGEDLETYESTSSNEIPESLQADENDVHSSRIATLKVLEGIFEKFASTLPDGKTKMTFGLVGYPNVGKSSTINALVGSKKVSVSSTPGKTKHFQTINLSEKVSLLDCPGLVFPSFATTQADLVLDGVLPIDQLREYTGPSALMAERIPKEVLETLYTIRIRIKPIEEGGTGVPSAQEVLFPFARSRGFMRAHHGTPDDSRAARILLKDYVNGKLLYVHPPPNYPNSGSEFNKEHHQKIVSATSDSITEKLQRTAISDNTLSAESQLVDDEYFQENPHVRPMVKGTAVAMQGPVYKGRNTMQPFQRRLNDDASPKYPMNAQGKPLSRRKARQLTALELGVSPEALSSATSKKHNKKNKRSKQRSGVVIDDY
Protein: Sodium/potassium-transporting ATPase subunit alpha (C0PUF8)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004415}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004415}. Cell membrane {ECO:0000256|RuleBase:RU362084}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362084}.
Interaction partners:
Sequence:
ESKHLLVMKGAPERILDRCSTILIQGKEQPLDDEMKDSFQNAYMELGGLGERVLGFCHFQLPDDQFAEGFQFDCEEVNFPTENLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNEVDPRDAKACVVHGGDLKDLSAEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLFFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSKTDKLVNERLISIAYGQIGMIQALAGFFTYFVILAENGFLPSRLLGIRVDWDNKFCNDLEDSYGQQWTYEQRKIVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMRNKILIFGLFEETALAAFLSYCPGMGIALRMYPLKPSWWFCAFPYSLLIFIYDEIRKLIIRRSPGGWVERETYY
Protein: D-galactonate dehydratase family member VSWAT3_13707 (A5KUH4)
Organism: Vibrionales bacterium (strain SWAT-3)
Function: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.
Interaction partners:
Sequence:
MKETIISDIHCIITKPDRHNLITVVVETNEGVTGFGCATFQQRPLAVKTMVDEYLKPILIGKNANNIEDLWQMMMVNAYWRNGPVINNAISGVDMALWDIKAKLAGMPLHQLFGGKSRDAIPVYTHATSDTMEGIYDLVEGFLEKGYKHIRCQLGFYGGVPTDLHTTQNPTEGSYYDQDQYMDNTLTMFKSLREKYGNQFHILHDVHERLFPNQAIQFAKEVEQYKPYFIEDILPPNQTEWLDNIRSQSSVSLGLGELFNNPEEWKSLIANRRIDFIRCHVSQIGGITPALKLGHLCQNFGVRIAWHCPPDMTPIGAAVNTHLNVHLHNAAIQEHVEYNGNTHKVFPNAAEPINGYLYASEIAGIGVEIDREAAAEFPVMYRPHEWTQSRLPDGAIHTP