wanglab/gogpt-training-data huggingface dataset:
Protein: Nuclear mRNA export protein THP1 (Bud site selection protein 29) (Q08231)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the SAC3-THP1 complex, which functions in transcription-coupled mRNA export from the nucleus to the cytoplasm. SAC3-THP1 functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), by association with components of the nuclear mRNA export machinery (MEX67-MTR2 and SUB2) in the nucleoplasm and the nucleoporin NUP1 at the nuclear basket. THP1 binds to RNA in vitro.
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:12206772, ECO:0000269|PubMed:12411502, ECO:0000269|PubMed:14562095}. Note=Localizes to the nuclear pores.
Interaction partners:
- Nuclear mRNA export protein SAC3
- 26S proteasome complex subunit SEM1
- SAGA complex subunit SUS1
- Cell division control protein 31
- Cop9 signalosome complex subunit 12
Sequence:
MDMANQLLDELAHGNFSHLTLNLSQNGREIAILQKQLTGFDDKQLETFVEQHPAMPNDTRFKIMCTSFLNYARDVDPWSAWSSSDLIFEFYQCLINCLINDNAPHIEMLIPVATRETEFIINLAGKLDSFHLQLHTRSHQFLSHISSILSRLFNSIKPPRGNASSTNIPGKQRILLYLVNKLNNIYFRIESPQLCSNIFKNFQPKSMLAHFNEYQLDQQIEYRYLLGRYYLLNSQVHNAFVQFNEAFQSLLNLPLTNQAITRNGTRILNYMIPTGLILGKMVKWGPLRPFLSQETIDNWSVLYKHVRYGNIQGVSLWLRQNERHLCARQLLIVLLEKLPMVTYRNLIKTVIKSWTTEWGQNKLPYSLIERVLQLSIGPTFEDPGAQEITIYNGIHSPKNVENVLVTLINLGLLRANCFPQLQLCVVKKTTMIQEIVPPVNERITKMFPAHSHVLW
Protein: Plant-specific TFIIB-related protein 1 (Plant-specific TFIIB-related protein) (AtPBRP) (TFIIB-related protein PBRP1) (O23215)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plant-specific TFIIB-related protein that may be involved in an intracellular signaling pathway between plastids and the nucleus. May act as general transcription factor (GTF) of RNA polymerase I-dependent transcription and rRNA synthesis. Forms a ternary complex with TBP2 and the rDNA promoter region.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000269|PubMed:12697827}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000269|PubMed:12697827}. Nucleus {ECO:0000269|PubMed:12697827}. Note=Localizes to the nucleus under conditions of proteasome inhibition. {ECO:0000269|PubMed:12697827}.
Interaction partners:
- Plant-specific TFIIB-related protein 2
- Plant-specific TFIIB-related protein PTF2
- DNA-directed RNA polymerase II subunit 4
- Transcription initiation factor IIF subunit alpha
- Transcription initiation factor IIA subunit 2
- General transcription and DNA repair factor IIH subunit TFB2
- DNA-directed RNA polymerases II, IV and V subunit 11
- TATA-box-binding protein 2
- General transcription factor IIH subunit 2
- General transcription and DNA repair factor IIH subunit TFB4
Sequence:
MKCPYCSSAQGRCTTTSSGRSITECSSCGRVMEERQTQNHHLFHLRAQDTPLCLVTSDLQTAAQPSPEDEEDPFEPTGFITAFSTWSLEPSPIFARSSLSFSGHLAELERTLELASSTSNSNSSTVVVDNLRAYMQIIDVASILGLDCDISEHAFQLFRDCCSATCLRNRSVEALATACLVQAIREAQEPRTLQEISIAANVQQKEIGKYIKILGEALQLSQPINSNSISVHMPRFCTLLQLNKSAQELATHIGEVVINKCFCTRRNPISISAAAIYLACQLEDKRKTQAEICKITGLTEVTLRKVYKELLENWDDLLPSNYTPAVPPEKAFPTTTISTTRSTTPRAVDPPEPSFVEKDKPSAKPIETFDHTYQQPKGKEDKQPKFRQPWLFGTASVMNPAEMISEPAKPNAMDYEKQQLDKQQQQQLGDKETLPIYLRDHNPFPSNPSPSTGISTINWSFRPSVVPGSSSNLPVIHPPKLPPGYAEIRGSGSRNADNPHGDF
Protein: Ribosomal RNA-processing 7 protein (Q8GYF9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKETRKLKKSNLPKEETVGKKIQRKKNEKVSNVELSEDPQAAQLQAKSSEKPNRKKIQKGKEIKSSPADGKLSGKMKKRKEKVGNVDISEPILEAISTEKVKEKKGKMNKTKKKRKAEEITRSSVEDLKRESKFKKSNKKKKMDMTSKKENKIEEEEDVYQISSGDEDCTRGMKKWVSDYYEGRPGLDELQKRIDDFMTAHEERLEQEKQDKEAKAAEGGWTVVVHHKGRKKTTESETGTAVGSFSQAALEDKIAKKKQSEPVAHGFYRFQRRDAQRNELLALQSKFEEDKKRIQQLRAARRFKPF
Protein: Small ribosomal subunit protein mS22 (28S ribosomal protein S22, mitochondrial) (MRP-S22) (S22mt) (Q9CXW2)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:P82649}.
Interaction partners:
- Small ribosomal subunit protein mS39
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein mS31
- Small ribosomal subunit protein mS34
- Small ribosomal subunit protein mS40
- Small ribosomal subunit protein mS26
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS11m
Sequence:
MAAVRTPLSLWRFQLGSRRARRVCTRATAQRHPDALLATRPQPFEVGQPRRLLSSEAESGSSEVKKPAFMDEEVQRILTKITGLDLQKTFRPAIQPLKPPTYKLMTQAQLEEATRLAVEAAKVRLKMPPVLEERKPINDVLAEDKILEGTETNKYVFTDISYNIPHRERFIVVREPSGTLRKASWEERDRVIQIYFPKEGRRVLPPVIFKDENLKTMYSQDRHADVLNLCVAQFEPDSAEYIKVHHQTYEDIDRHGKYELLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDATSLVQLYHMLHPDGQSAQEAKEQAAEGVDLIKVFAKTEAQRGAYIELALQTYQEIVTSHSAAS
Protein: Phospholipid-transporting ATPase (EC 7.6.2.1) (Q7KTG5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}.
Interaction partners:
Sequence:
MPSANTEDLRRKFLVVQQQRSAPPNLTGDTLSSGIPNASASSATTSLMMTTSTGLGGVAMGAGEPERTYVFPGGNPVVGSAPGGGGQGIPGVAMAAPSRGHARSISHGGGAIVGANGRPIKSAMKGHQRAFSQGQITDSPPGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVILQSKRERSRESPIMGLRIRL
Protein: Condensin complex subunit 1 (Q9VAJ1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Structural maintenance of chromosomes protein
- Condensin complex subunit 2
- Chromosome associated protein G, isoform F
- Structural maintenance of chromosomes protein
- Condensin-2 complex subunit
- Chromosome associated protein H2, isoform E
- DNA polymerase alpha catalytic subunit
- Structural maintenance of chromosomes protein
- Structural maintenance of chromosomes protein
- Structural maintenance of chromosomes protein 5
Sequence:
MEESHDFQFVLPLNASDLINSSGDQYYVKEIFGAQEIPAKLQECKRKVHLGDPFYIFEHFDLYYSIIEARGSDGASAQNLMRSFDLLYLTVEKLFQDLQPLLTASEPMSNQQRNSYLNLTKMTLFLQVSTVKKINNSVQQAMRDQQLNVQKKRAKPSEGLEQFPNWEVKRGKFLVQLFNVLQCPLEKLWSPPVAEEDFINLLCDPCYRTIELLPLRMDNKHVFDTIFQILGTSIKRFNQAMTFPVRILQILRGTEHAAHSVAAGILLLHEEYGISSVFSILIKSIVDALRMDSSDSSVSKHFSNFLAEFSNIAPSLIVPHLEKLAEDLLDCQSHTLRNCVLQIIGDTVVSELTSEDLSEELKEVRNEFLEHLMAHILDISAHVRSKVLSIWHHLKTQHAIPLNFLTRVLEEAIGRLEDKSSLVRRAAMHLIKSALESNPYSSKLSIDELRAKHEHEVQAMEKLNEVLEEERKQEEKLNDEFSSLAPELLPFIEENLTEFPDMQFDKEESDETLMERIIPLMREKNYKDVIVLVRKVDFLAGNQNMSSLLKHEEHCVYVLALLKTYHLLAAGFKQSSEEMLQQIKTVQFLKDSIDFAVLMTSAFPKLHEMLMSKTNTDVFEAVDLFTTGYMFGIHGTESGMQRMLQLVWSSDKEKRDAVSDAYKRVLFSTDQTGRAHAIKVVQNLSKFLSEIEYGHYTALESLMTEWVLGGDIDAAVIQVLFERFTLKLEGTTSNESRLSLQLLIMASQSKSSIVSANTAIIEDIAVGERVRRDPRIFTSCLQLLVNSIDANNTAKYYKRQNSDAEFVGKITRLFLDFFFHRSLYDFDALAMSVFEYFYRMCQAPDVIAQQLVTALLKQFNESWLVKEAAAIVPSPDKADTETVPDSQPLEIPHSQTLTPTQTQADSQSQMQGTLIPVYLVSRLIFCIGYMTIKEMIFLDMDIYNNMKYRDELTALEERKNRNQQAGSSHNAARLTLNMSAMEVRKRLSGVAAEPQQEPDDDLVGATAEDNIAEEIHGICEDMLLYNPDALLSKLAPFIIEICKRPGEFGDPTLQQAATLALARLMTVSSRFCESNMSFLMNILNLTKNIRIKCNTVVGLSDLTFRFPNIIEPWTGHFYAQLHESNTELRLTAVKMLSHLILNEMIRVKGQIADMALCIVDGNEEIRNITKQFFKEIANKSNILYNVLPDIISRLGDINLNLDEDKYRIIMSYILGLIQKDRQIETLVEKLCLRFPVTRVERQWRDIAYCLGLLTYNERAVKKLMDNMQHYRDKVQVDEVYQSFKLIISNTNKLAKPELKAVVTEFENRLNECLQVNPDTAAQGDQESTPEGQGNRTRAAPRTKKGGRKPAANRNNTVRGRGRRARRDSTSEESFSSSSSD
Protein: Early growth response protein (J7JV33)
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU363046}.
Interaction partners:
Sequence:
MAAAKAEMQLLPPLQISDPFGAFPHSPPAMDTHYPKLEEMMLLSGGGPQFLAPPGASESAGFGAAGEPGEQHFEHLGADTFPEISLNNEKTLPETSYPNQTTRLPPITYTGRFSLEPAPNSSNPLWPEPLFSLVSGLVGMANAPPTSTPTSSSPSSSSQSSPLSCSVQASENNPIYSAAPTFPNSSSDIFPESQTQSFPNPSGAPIQYPPPAYPTAKANFQVPMIPDYLFPQQQAELSLVPADQKPFPALETRAQQPSLTPLSTIKAFATQTGSQELKTLNANYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKVEKAAPASTASPIPAYSSSVTTSYPSSITTTYPSPVRTAYSSPAPSSYPSPVHTTFPSPSIATTYPSGTATFQTQVATSFSSPGVANNFSSQVTSALSDINSAFSPRTIEIC
Protein: Probable GTP diphosphokinase RSH3, chloroplastic (EC 2.7.6.5) (RelA/SpoT homolog 3) (AtRSH3) (ppGpp synthetase RSH3) (Q9SYH1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses ppGpp (guanosine 3'-diphosphate 5'-diphosphate) synthetase activity in vitro and is able to functionally complement E.coli relA mutants. May be involved in a rapid plant ppGpp-mediated response to pathogens and other stresses.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Nucleoside diphosphate kinase 1
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase II, chloroplastic
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- Inosine triphosphate pyrophosphatase
- Alkaline-phosphatase-like family protein
- Large ribosomal subunit protein bL31c
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Large ribosomal subunit protein bL28c
- 50S ribosomal protein L33
Sequence:
MVVATTIALYASPASTVCSTAHQINAHISCDLDLNSRSSSASSSTSSPTIGGLSLLFSGASVKSSSSSSSSHPSVGEELASIRHDRSEDRTLSGSFCYSPSKFIGSSYLKRDHQSPVSVLHGPISSGNSPPMRISRDRNLDGGSALRVGSSRLFNGFVRKAIGSCVDYDTDSVLVDEQLPFTMDDGFEGERRQPYARDLLRRAQLKHKIFEDESVIKAFYEAEKAHRGQMRATGDPYLQHCVETAMLLADIGANSTVVVAGILHDTLDDSFMSYDYILRTFGSGVADLVEGVSKLSQLSKLARENNTACKTVEADRLHTMFLAMADARAVLIKLADRLHNMMTLYALPPVKRQRFAKETLEIFAPLANRLGISSWKVKLENLCFKHLHPDQHHEMSDMLEDSFDEAMITSAIEKLEQALKKEGISYHVVSGRHKSLYSIYCKMLKKKLTMDEIHDIHGLRLIVDNEKDCYKALGVVHKLWSEVPGKLKDYISHPKFNGYQSLHTVVMGDGTIPLEVQIRTKEMHLQAEFGFAAHWRYKEGDCKHSSFVLQMVEWARWVVTWHFETMSKDGSSICSSEPLCSFPSHAEDCPFSYKPSGNQEGPVYVIVIENEKMTVQEFPENSTVSDLLRRAGPGSSRWSMYSIPAKEELRPRLNQTPVSDLKCKLKMGDVVELTPAIPDKSLTEYREEIQRMYDRGLAFSRPHRAATGTMVGWGS
Protein: Uncharacterized protein (Q584C1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPRQRSFLSSVLKGRRNTPTYYSGRGDMAGNPDILAEAACCGRPDAEWAWLRLLCFVCVSSTVGVWLWQVYFYKQAMFFKDEPWSPFKN
Protein: Ferric reduction oxidase 8, mitochondrial (AtFRO8) (EC 1.16.1.7) (Ferric-chelate reductase 8) (Q8VY13)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ferric chelate reductase probably involved in iron reduction in leaf veins for transport. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates.
Subcellular location: Mitochondrion membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Metal transporter Nramp3
- Vacuolar iron transporter 1
- Fe
- Metal-nicotianamine transporter YSL2
- Nicotianamine synthase 1
- Metal transporter Nramp4
- Fe
- Ferritin-1, chloroplastic
- Probable metal-nicotianamine transporter YSL6
- Protein DETOXIFICATION 43
Sequence:
MAKVLTLLVLRLLMNLLLIGWISLWIIKPTTIWIQSWRQAEDTARHTFFGYYGLNFAVFSFPPIALSIVGLIYLSLLPQHHHPTRGGRGAAITVSRPAIINSFIGIVSCFEILALLLFLLFLAWNFYARVSNDFKKLMPVKTMNLNLWQLKYYRVATRFGLLAEACLSLLLFPVLRGLSMFRLLNIEFAASVKYHVWFGTGLIFFSLVHGGSTLFIWTITHHIEEEIWKWQRTGRVYVAGLISLVTGLLMWITSLPQIRRKNFEVFYYTHHLYIVFLVAFLFHAGDRHFYWVLPGMFLFGLDKILRIVQSRSESCILSANLFSCKAIELVLPKDPMLNYAPSSFIFLNIPLVSRFQWHPFSIISSSSVDKHSLSIMMKCEGDWTNSVYNKIEEAANCENKINNIIVRVEGPYGPASVDFLRYDNLFLVAGGIGITPFLSILKELASKNRLKSPKRVQLVFAVRTFQDLNMLLPIASIIFNPIYNLNLKLKVFVTQEKKPSNGTTTLQEFLAQSQVQSIHLGTDEDYSRFPIRGPESFRWLATLVLITVLTFLGFLIGLSHFFIPSEHKNHSGVMKLAASGAMKTAKEKVPSWVPDLIIIVSYVIAISVGGFAATILQRRRKHKEAPRMSKEVVIKPEERNFTELKPIPITEEHEIHIGERPKLEEIMSEFEKNLRGWSSVGVLVCGPESVKEAVASMCRQWPQCFGVEDLRRSRMKMNLNFHSLNFNL
Protein: Cation/calcium exchanger 3 (AtCCX3) (Protein CATION CALCIUM EXCHANGER 3) (Protein CATION EXCHANGER 9) (Q9LJI2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Endomembrane-localized H(+)-dependent K(+) and Na(+) transporter. May have a function associated with the pollen vacuole during tube elongation and polarized top growth.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:18775974}; Multi-pass membrane protein {ECO:0000269|PubMed:18775974}. Endosome membrane {ECO:0000269|PubMed:18775974}; Multi-pass membrane protein {ECO:0000269|PubMed:18775974}.
Interaction partners:
- Magnesium/proton exchanger
- Vacuolar cation/proton exchanger 2
- Vacuolar cation/proton exchanger 5
- Sodium/calcium exchanger NCL
- Putative vacuolar cation/proton exchanger 6
- Vacuolar cation/proton exchanger 4
- Vacuolar cation/proton exchanger 3
- Vacuolar cation/proton exchanger 1
- Non-phototropic hypocotyl-like protein
- Cation/H
Sequence:
MSAVSFLYSSKTPKFRGVFNGICALVLFCFFFDRSELLRNPLLRNASFVNGGSGSTSGGITQFMVIRRNARQIETNGSGNNSSLSSSSTVLCSGLHKHMGYADQCEFLKANPICSPDGFFDYLSFFYCSCRDFSILGYMMLGVWLVALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFASIAAFVGTDKGEVGLNSVLGGAVFVTSVVVGIVSLCVADKEVKIDKNCFIRDLSFFLFSLVSLLVILMVGRVTVRIAIAFVSIYVVYAFLVAANVILRKHAKRFKLEALTPLLPMQGSVFSPSVGEDMPMNTPLIETETEDGPPRLQSLPQWMWASNVAIYSNHFAKVSVHDEDRPPWGWIDDTAEVESSSCTKFTSLLEIPLTIPRRLTIPSVEEDTWSKTYAVASVSLAPVLLASLWSSQDDVSLQACGVAYFFSVVIGSTLGFLAYKNTEPDHPPRRFLIPWVLGGFIMSIVWFYMIANELVALLVTFGEIYGINPSILALTVLAWGNSMGDLVSNIALTMNGGDGVQIALSGCYAGPMFNTLVGLGMSMLFGAWSKSPDTYMLPEDKSLFYTLGFLVLGLVWAMVILPRNDMQPSRTLGVGLIAIYLIFVTFRLSCAMGFIPWAA
Protein: Kell blood group antigen (Kell blood group, metallo-endopeptidase) (A0A077QP03)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEGGDQSEEEPRERSQAGGMGTLWSQESTPEERLPVEGSRPWAVARRVLTAILILGLLLCFSVLLFYNFQNCGPRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRAKETNNSFQELATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMGASEWALKPELARQEYNDIQLGSSFLQSVLSCVRSLRARIVQSFLQPHPQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIFYQLLLPGGCLACDNHALQEAHLCLKRHYAAFPLPSRTSFNDSLTFLENAADVGGLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQVMCRKPSPQDSHDTHSPPHLRVHGPLSSTPAFARYFRCARGALLNPSSRCQLW
Protein: Antitoxin phd (Addiction protein pdh) (Prevent host death protein) (Q06253)
Organism: Escherichia phage P1 (Bacteriophage P1)
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. A labile antitoxin that binds to cognate doc toxin and neutralizes its ability to phosphorylate host EF-Tu. Does not reverse phosphorylation. Bacteriophage P1 lysogenizes bacteria as a low-copy number plasmid; phd and doc proteins function in unison to stabilize plasmid number by inducing a lethal response to P1 plasmid prophage loss.
Interaction partners:
Sequence:
MQSINFRTARGNLSEVLNNVEAGEEVEITRRGREPAVIVSKATFEAYKKAALDAEFASLFDTLDSTNKELVNR
Protein: NGFI-A-binding protein homolog (dNAB) (Q59E55)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcriptional regulator that can both act as a coactivator or a corepressor depending on the context. Lacks DNA-binding domains and acts by associating with other transcription factors such as rotund (rn) and squeeze (sqz). Acts as a coactivator of sqz and is required to limit the number of neurons that express the LIM-homeodomain gene apterous and to specify Tv neuronal fate. Acts as corepressor of rn in wing development and is required to limit the expression of wingless (wg) in the wing hinge, where wg plays a mitogenic role.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Stripe, isoform D
- Zinc finger protein squeeze
Sequence:
MEASSNPTTPTTAVATTTSTSSPSPAASTSSKGHSQSATASASASATQSQLLTTSLEMPKTEDLYNLSVASGLSEGQRSLSGAPSASSSPIMSPQGKIFGRNANGTMITTSRPGNEAEVQLYRVLQRASLLAYYDTLLEMGGDDVQQLYDAGEEEFLEIMALVGMASKPLHVRRLQKALHEWANNPGLFQGPMMPHLGLCETPPKPALIFNPDTTPALPRQKFPSFNPSGSSFMPSPVPPAPLPASASVPAPTVPLATQISCPSAPSVPLPLVLPPNPLTSSPHPSANSNLPANTAHQVSSSSPQLTPVLTEAQIQRITMCADKIGRQLPQREPRAQTTRKRTTRELEQVIAMGEQDPRRMDEIRKYSAIYGRFDCKRRPEKPLTLHEVCVNEAAAQLCRNPQTIWLLTRRDELFPLARQIVKDAGFGHSASIARYGGLLTQLPSQGAGLGGGRAPGDTDCESSDAAVPSKRQRLSSTEAAQLPLDLNREAVEDSRYNLFAMYQKFAKPPFDLSEIAKFSVSKAADYEDNDSRFSFSNSSSPTMPTPCNGMEGERSPVSRQMETSSPPRESVDLSGTSSGAALSGVQVISAAGDNIIAVANPALALSPALNEVLALKRSAASPET
Protein: Calcium-binding protein 2 (CaBP2) (Q9NPB3)
Organism: Homo sapiens (Human)
Function: Required for sound encoding at inner hair cells (IHCs) synapses, likely via inhibition of the inactivation of voltage-gated calcium channel of type 1.3 (Cav1.3) in the IHCs. Required for the normal transfer of light signals through the retina (By similarity).
Subcellular location: Cytoplasm, perinuclear region {ECO:0000269|PubMed:19338761}. Cell membrane {ECO:0000269|PubMed:19338761}; Lipid-anchor {ECO:0000269|PubMed:19338761}; Cytoplasmic side {ECO:0000269|PubMed:19338761}. Golgi apparatus {ECO:0000269|PubMed:19338761}.
Interaction partners:
- Protein S100-G
Sequence:
MGNCAKRPWRRGPKDPLQWLGSPPRGSCPSPSSSPKEQGDPAPGVQGYSVLNSLVGPACIFLRPSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELIEISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMSR
Protein: Small ribosomal subunit protein bS16m (28S ribosomal protein S16, mitochondrial) (MRP-S16) (S16mt) (Q9Y3D3)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25838379}.
Interaction partners:
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein mS34
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein bL9m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein uS7m
- Large ribosomal subunit protein bL20m
- Small ribosomal subunit protein mS29
Sequence:
MVHLTTLLCKAYRGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSHGEKLVALNLDRIRHWIGCGAHLSKPMEKLLGLAGFFPLHPMMITNAERLRRKRAREVLLASQKTDAEATDTEATET
Protein: Activator of basal transcription 1 (hABT1) (Basal transcriptional activator) (Q9ULW3)
Organism: Homo sapiens (Human)
Function: Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Probable ATP-dependent RNA helicase DDX49
- Ribosomal RNA processing protein 36 homolog
- ESF1 homolog
- Probable ATP-dependent RNA helicase DDX10
- Bystin
- U3 small nucleolar RNA-associated protein 25 homolog
- KRR1 small subunit processome component homolog
- ATP-dependent RNA helicase DHX15
- Nucleolar protein 14
- U3 small nucleolar RNA-associated protein 6 homolog
Sequence:
MEAEESEKAATEQEPLEGTEQTLDAEEEQEESEEAACGSKKRVVPGIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEDRFVRRKKKAAAAAGGKKRSYTKDYTEGWVEFRDKRIAKRVAASLHNTPMGARRRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLQSVERGQRFLAADGDPARPDGSWTFAQRPTEQELRARKAARPGGRERARLATAQDKARSNKGLLARIFGAPPPSESMEGPSLVRDS
Protein: Mortality factor 4-like protein 2 (Liver regeneration-related protein LRRG00119) (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Q6QI89)
Organism: Rattus norvegicus (Rat)
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00972}.
Interaction partners:
- Chromatin modification-related protein MEAF6
- YEATS domain containing 4
- DNA methyltransferase 1-associated protein 1
- MRG domain binding protein
- Vacuolar protein sorting-associated protein 72 homolog
- Inhibitor of growth protein 3
- RuvB-like helicase
- Histone acetyltransferase KAT5
- Enhancer of polycomb homolog 1
- Enhancer of polycomb homolog
Sequence:
MSSRKQASQTRGQQSAEEDNFKKPTRSNMQRSKMRGAASGKKSAGSQPKNLDPALPGRWGGRSAENPPSGSVRKTRKNKQKTPGNGDGGSTSEVPQPPRKKRARADPTVESEEAFKSRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKSQGNVDNKEYAVNEVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAPMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL
Protein: Golgi phosphoprotein 3-like (GPP34-related protein) (Q9H4A5)
Organism: Homo sapiens (Human)
Function: Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Note=Phosphatidylinositol 4-phosphate (PtdIns4P)-binding mediates recruitment to Golgi membranes.
Interaction partners:
- Proprotein convertase subtilisin/kexin type 9
- Unconventional myosin-XVIIIa
Sequence:
MTTLTHRARRTEISKNSEKKMESEEDSNWEKSPDNEDSGDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKKRLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLVKKLQDSVLERWVNDPQRMDKRTLALLVLAHSSDVLENVFSSLTDDKYDVAMNRAKDLVELDPEVEGTKPSATEMIWAVLAAFNKS