wanglab/gogpt-training-data huggingface dataset:
Protein: DEAD-box ATP-dependent RNA helicase 50 (EC 3.6.4.13) (Q0DVX2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probably involved in resistance to biotic and abiotic stresses. Confers tolerance to oxidative stress and mediates pathogenesis-related (PR) genes expression. Exhibits RNA-dependent ATPase and ATP-dependent RNA helicase activities in vitro.
Interaction partners:
- Pescadillo homolog
- Os01g0785900 protein
- Os07g0475800 protein
- Ribosome biogenesis protein BOP1 homolog
- Ribosome biogenesis protein WDR12 homolog
- Expressed protein
- Os01g0375000 protein.
- Os05g0430400 protein
- DEAD/DEAH box helicase family protein, expressed
- Os03g0598200 protein
Sequence:
MEVAGAQAGILPLLLRHPASLRGSLSLSCGGARRSWAAAAATAEGGGGEEGRGYERVPMDTPGAYRLVDRATGRSVIVWGGTDDVSMPSPAVLSTTTRVPDRPKENGRSTSIGNFGRLKAQKVKVLARRSAHLKREDSGRISTSRFSESPSDESDEDGTYFERDRARNTRQNSRSRDDKTRGAHSLNSVLRQYRGADDLDFPGSEATSGSKRWGNISDVTFGRQNQRQKGPLDSGFFSRRSFKEIGCSDEILGALRSFGFPRPSHIQAMAYRPVLEGKSCIIGDQSGSGKTLAYLCPVVQNLRKEEVEGLHRSSPRNPRVVVLTPTAELASQVLNNCRSISKSGVPFRSMVATGGFRQKTQLESLDQELDVLIATPGRFLYLLQEGFVQLNNLRCVVLDEVDILYGEESFEQVLHQLITVAPLTTQYLFVTATLPLDIYNKVVETFPDCELIMGPGVHRTSSRLEEILVDCSGDDNEEKNPETAFSNKKSALVKIIEESPVRKTIIFCNKIETCRKVENALRRVDRKASQIKVLPFHAALDQQQRIANIKEFLNKQTADSMFLVCTDRASRGIDFANVNHVVLFDYPRDPSEYVRRVGRTARGASGNGKAFVFAVGKQVSLARRVMERNIKGHPLHDVPCV
Protein: ADF-H domain-containing protein (Q54FU0)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MPLKLDNESELREAQAALFNINSTGGWVMLNYVGPSTVHFAAGGENFEEIVNLLEDDQIQYGVLRIGNIEEKGTLKTTVRDVFFCWIGPGVGIIEKGKKTAFLGDAQQLLQPYHADITVLNKKNFNRENILDRSHPLSGSHVID
Protein: UBP1-associated protein 2C (Q9LKA4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus. Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs. May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:18278441, ECO:0000269|PubMed:18705666}. Note=Mainly localized into nuclear speckles.
Interaction partners:
- Ubiquitin-activating enzyme E1 2
- La-related protein 1B
- Probable receptor-like serine/threonine-protein kinase At4g34500
- Ubiquitin carboxyl-terminal hydrolase 1
- Large ribosomal subunit protein uL13y
- Gb|AAD20086.1 family protein with RNA binding
- Large ribosomal subunit protein eL15y
- Cystinosin homolog
- La-related protein 1C
Sequence:
MDMMKKRKLDENGNGLNTNGGGTIGPTRLSPQDARKIIERFTTDQLLDLLQEAIVRHPDVLESVRLTADSDISQRKLFIRGLAADTTTEGLRSLFSSYGDLEEAIVILDKVTGKSKGYGFVTFMHVDGALLALKEPSKKIDGRVTVTQLAASGNQGTGSQIADISMRKIYVANVPFDMPADRLLNHFMAYGDVEEGPLGFDKVTGKSRGFALFVYKTAEGAQAALADPVKVIDGKHLNCKLAVDGKKGGKPGMPQAQDGGSGHGHVHGEGMGMVRPAGPYGAAGGISAYGGYSGGPPAHHMNSTHSSMGVGSAGYGGHYGGYGGPGGTGVYGGLGGGYGGPGTGSGQYRMPPSSMPGGGGYPESGHYGLSSSAGYPGQHHQAVGTSPVPRVPHGGMYPNGPPNY
Protein: G-protein coupled receptor 182 (G10D) (NOW) (P31392)
Organism: Rattus norvegicus (Rat)
Function: Orphan receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Pro-adrenomedullin
Sequence:
MSVIPSSRPVSTLAPDNDFREIHNWTELLHLFNQTFSDCHMELNENTKQVVLFVFYLAIFVVGLVENVLVICVNCRRSGRVGMLNLYILNMAVADLGIILSLPVWMLEVMLEYTWLWGSFSCRFIHYFYLANMYSSIFFLTCLSIDRYVTLTNTSPSWQRHQHRIRRAVCAGVWVLSAIIPLPEVVHIQLLDGSEPMCLFLAPFETYSAWALAVALSATILGFLLPFPLIAVFNILSACRLRRQGQTESRRHCLLMWAYIVVFVICWLPYHVTMLLLTLHTTHIFLHCNLVNFLYFFYEIIDCFSMLHCVANPILYNFLSPSFRGRLLSLVVRYLPKEQARAAGGRASSSSSTQHSIIITKEGSLPLQRICTPTPSETCRPPLCLRTPHLHSAIP
Protein: Dystrobrevin, alpha (A0A8I6APF7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MIEDSGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNIELNVARLEAVLSTMFYQLNKRMPSTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYTEQSARSCFSQQKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSSGSPFITRSSDGAHGGCV
Protein: Transcription factor UDT1 (Basic helix-loop-helix protein 164) (OsbHLH164) (Protein UNDEVELOPED TAPETUM 1) (B9FXT3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcription factor that plays a crucial role in tapetum development. Required for male fertility and pollen differentiation within the developing anther. Plays a major role in maintaining tapetum development, starting in early meiosis. Required for pollen mother cell meiosis. May regulate the anther-specific cysteine protease CP1 and lipid-transfer proteins C4 and C6. Required for anther development. Functions in parallel with GAMYB to regulate early anther development. Functions upstream of the transcription factor TDR and may positively regulate its transcription.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:16141453}.
Interaction partners:
- Transcription factor EAT1
- Cytochrome P450 703A2
Sequence:
MPRRARARGGGGGGGEEVKVEDDFIDSVLNFGGGGGGEEDGDDGEEEQQQQQAAAAAMGKEFKSKNLEAERRRRGRLNGNIFALRAVVPKITKMSKEATLSDAIEHIKNLQNEVLELQRQLGDSPGEAWEKQCSASCSESFVPTENAHYQGQVELISLGSCKYNLKIFWTKRAGLFTKVLEALCSYKVQVLSLNTISFYGYAESFFTIEVKGEQDVVMVELRSLLSSIVEVPSI
Protein: Aminoglycoside N(6')-acetyltransferase type 1 (EC 2.3.1.82) (AAC(6')-Ij) (Aminoglycoside resistance protein) (Q44245)
Organism: Acinetobacter genomosp. 13
Function: Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin, kanamycin, tobramycin and netilmicin.
Interaction partners:
Sequence:
MNIMPVSESLMADWLGLRKLLWPDHDEAHLQEMQRLLQQTQSLQLLAYSDTQQAIAMLEASIRYEYVNGTQTSPVAFLEGIYVLPDYRRSGIATHLVQQVEAWAKPFGCIEFASDAALDNRISHAMHQALGFHETERVVYFKKHIG
Protein: Peptide YY (PYY) (Peptide tyrosine tyrosine) [Cleaved into: Peptide YY(3-36) (PYY-II)] (P68005)
Organism: Sus scrofa (Pig)
Function: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Subcellular location: Secreted.
Interaction partners:
- Neuropeptide Y receptor type 2
- Neuropeptide Y receptor type 1
- Neuropeptide Y receptor type 5
- Neuropeptide Y receptor type 1
- Pro-neuropeptide Y
- Appetite-regulating hormone
- Pro-glucagon
- Cholecystokinin
- G-protein coupled receptor 83
- Pancreatic polypeptide prohormone
Sequence:
YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY
Protein: Proton-coupled zinc antiporter SLC30A2 (Solute carrier family 30 member 2) (Zinc transporter 2) (ZnT-2) (Q62941)
Organism: Rattus norvegicus (Rat)
Function: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity. Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells (By similarity). By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution (By similarity).
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000305|PubMed:8617223}; Multi-pass membrane protein {ECO:0000255}. Zymogen granule membrane {ECO:0000305|PubMed:20133611, ECO:0000305|PubMed:8617223}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000305|PubMed:8617223}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000305|PubMed:8617223}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9BRI3}; Multi-pass membrane protein {ECO:0000255}. Note=Localization to lysosomes is induced by TNF-alpha. {ECO:0000250|UniProtKB:Q9BRI3}.
Interaction partners:
- Zinc transporter ZIP13
- Zinc transporter ZIP4
- Zinc transporter 6
- Fatty acid synthase
- Metal cation symporter ZIP8
- Zinc transporter ZIP6
- Zinc transporter ZIP11
- Proton-coupled zinc antiporter SLC30A9, mitochondrial
Sequence:
MASRSFFGALWKSEASRIPPVNLPSVELAVQSNHYCHAQKDSGSHPNSEKQRARRKLYVASAICLVFMIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFSLWVSSRPATKTMNFGWQRAEILGALLSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNIIMGLALHQSGHGHSHGHSHEDSSQQQQNPSVRAAFIHVVGDLLQSVGVLVAAYIIYFKPEYKYVDPICTFLFSILVLGTTLTILRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSVHIAIAQNVDAQAVLKVARDRLQGKFNFHTMTIQIESYSEDMKSCQECQGPSE
Protein: Homeodomain interacting protein kinase 1 (D6RC95)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHRSNVSLLEPYQ
Protein: Protein HIRA (TUP1-like enhancer of split protein 1) (Q61666)
Organism: Mus musculus (Mouse)
Function: Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Subcellular location: Nucleus {ECO:0000250}. Nucleus, PML body {ECO:0000250}. Note=Primarily, though not exclusively, localized to the nucleus (By similarity). Localizes to PML bodies immediately prior to onset of senescence (By similarity). Localizes specifically to the male nucleus in fertilized eggs. This localization persists from the initiation of sperm nucleus decondensation to pronucleus formation. {ECO:0000250, ECO:0000269|PubMed:15922569, ECO:0000269|PubMed:9731536}.
Interaction partners:
- Calcineurin-binding protein cabin-1
- Ubinuclein-1
- Histone chaperone ASF1A
- Histone chaperone ASF1B
- Histone H3.3
- Ubinuclein-2
Sequence:
MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSSSLAGTMLSSPSGQQLLPLDSSTPSFGASKPCTEPVAATSARPTGESVSKDSMNATSTPAASSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPSLTSVIPTAVERLKEQNLVKELRSRELESSSDSDEKVHLAKPSSLSKRKLELEVETVEKKKKGRPRKDSRLLPMSLSVQSPAALSTEKEAMCLSAPALALKLPIPGPQRAFTLQVSSDPSMYIEVENEVTTVGGIRLSRLKCNREGKEWETVLSSRVLTAAGSCDVVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHRQVVVVKEESLHSILSGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHCSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK
Protein: AT3g15090/K15M2_24 (GroES-like zinc-binding alcohol dehydrogenase family protein) (Oxidoreductase-like protein) (Q9LK96)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DEAD-box ATP-dependent RNA helicase 28
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH9
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH3
- DExH-box ATP-dependent RNA helicase DExH7, chloroplastic
- DExH-box ATP-dependent RNA helicase DExH1
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH4
- ATP-dependent RNA helicase DEAH13
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH2
- DExH-box ATP-dependent RNA helicase DExH4, chloroplastic
- Probable pectin methylesterase CGR3
Sequence:
MRVMRSLRGNSGAGLVFRPARLNSLRSVFTGCRAVILPRFGGPEVFELRENVPVPNLNPNEVLVKAKAVSVNPLDCRIRAGYGRSVFQPHLPIIVGRDVSGEVAAIGTSVKSLKVGQEVFGALHPTALRGTYTDYGILSEDELTEKPSSISHVEASAIPFAALTAWRALKSNARITEGQRLLVFGGGGAVGFSAIQLAVASGCHVTASCVGQTKDRILAAGAEQAVDYTTEDIELAVKGKFDAVLDTIGGPETERIGINFLRKGGNYMTLQGEAASLTDKYGFVVGLPLATSLLMKKKIQYQYSHGIDYWWTYMRADPEGLAEIQRLVGAGKLKIPVEKTFPITDVVAAHEAKEKKQIPGKVVLEF
Protein: Protein sym1 (O14142)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Phosphoglycerate kinase
Sequence:
MFSRFATRYNALFEKAPIMTMCLTAGTLGGISDAVAQGLTIYQTNKNAMIGLDGVRLNTHPEIPSIKRVLQFVTFGFAISPFQFRWLRLLSAKFPIEKGAINVVKRVLLDQAVFAPFGTAFFFSWMTLAEGKGFRGAYDKLQAVFWPTLKANYMVWPFFQTVNFWLMPLQYQMPFACTVAIFWNIFLSLKNASSMQESGSQEIELF
Protein: Solute carrier family 2, facilitated glucose transporter member 5 (Fructose transporter) (Glucose transporter type 5, small intestine) (GLUT-5) (Q9WV38)
Organism: Mus musculus (Mouse)
Function: Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency (By similarity). Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:18496516, ECO:0000269|PubMed:19091748, ECO:0000269|PubMed:26071406}; Multi-pass membrane protein {ECO:0000269|PubMed:18496516}. Cell membrane {ECO:0000269|PubMed:12031501, ECO:0000269|PubMed:19091748}; Multi-pass membrane protein {ECO:0000305}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P43427}. Note=Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi (PubMed:18496516, PubMed:26071406). Transport to the cell membrane is dependent on RAB11A (PubMed:26071406). {ECO:0000269|PubMed:18496516, ECO:0000269|PubMed:26071406}.
Interaction partners:
- Sodium/glucose cotransporter 1
- Ketohexokinase
- Sodium/myo-inositol cotransporter 2
Sequence:
MEEKHQEETGELTLVLALATLIAAFGSSFQYGYNVAAVNSPSEFMQQFYNDTYYDRNEENIESFTLTLLWSLTVSMFPFGGFIGSLMVGTLVNKLGRKGALLFNNIFSILPAILMGCSQIAQSFELIIISRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFGLRSLLANEDGWPVLLGLTGVPAGLQLLLLPFFPESPRYLLIQKKDEAAAERALQTLRGWKDVHLEMEEIRKEDEAEKAAGFISVWKLFTMQSLRWQLISMIVLMAGQQLSGVNAIYYYADQIYLSAGVKSDDVQYVTAGTGAVNVFMTILTIFVVELWGRRFLLLVGFSTCLIACLVLTAALALQNTISWMPYISIVCVIVYVIGHALGPSPIPALLITEIFLQSSRPAAYMIGGSVHWLSNFTVGLIFPFIQMGLGPYSFIIFATICFLTTIYIFMVVPETKGRTFIEINQIFTMKNKVSDVYPKKEEELGALPHAILEQ
Protein: Gfd2/YDR514C-like C-terminal domain-containing protein (J9VQ28)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Interaction partners:
Sequence:
MDDNNPGGKVFPDTTMRVESKEGLSLVKDAYMRQMDVMYQWPNSLNPWQAGAIKSIFSNTALYDPGHPLHPGKEGITLYLGYDKTNRPRLLFSLKQVEYIQYYINAMRLSTPSWVEYYQRRAELIADGSQESLAELEEMGEPNYEDGKDDWVPIPDMVLPAELFIKIEEIYVQSHFHLGKINKQLEKDSKIAERHERNGMALPVFDSKRFDDILSLPIPDPNANPEQEKEKEKNRQIQDEKDQEKMAMKVRAQKEQEEKRRQEDADWREQEERVRKHREEMEREAIERERRVEREENGTGETLDKAAEFVDSEINDSSVNFVDEDERQDREKISARYHNACQRALIIAMYGGWKYFDSEENGPQQEEDVEGVMEEEEKKVNKLEKPSHLGRTVFVALSVTRWEKDPKVVLEVGWSAIYWQEDKWYGPPDALHTKPEFEEMRDYGHIIVQDHILDKYNGETRPDYRDKYCYGDSIPVPKNELKQTLKAKLQDIWKKGGKGPIFIVTHTPKGEEHDFCDVGLDITTADPDLHPDTQEILPDEDPNASNAVYMVNTATLFGAIEGVESSYLPPSPSNPHPLVIAGRSEKSLQHAALIVFGNSDERRKPTFVGNAGNDAFYTLQLLLAILFGSTLDELKAAYEEDNINPDFFKASADPTRPDKIEEDKVELVRAAPSRPPGLEGYIEVDREDMLPDDERIIYDDPDWVEEEDVIGVHYEDDEGNLLPLPHGPDHVGSDEEERTNVLDAVEV
Protein: Muscarinic acetylcholine Receptor, B-type, isoform A (RH14214p) (Q9VHW1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Muscarinic acetylcholine receptor DM1
- 5-hydroxytryptamine receptor 2A
- Allatostatin C receptor 2, isoform F
Sequence:
MRSLNKSAGEEELTGLNGNSSDSIYTIKNKWITDWSLRRERDKLCSFIFKRVLTHTECKRLLEAAKIYGESSDFNSWPVNEQLQWYRNFDVNNTNLLLAVRNQSSDGGSTMSGSSSDSEILGPVLPPFALWQTILIAICLAICIILTVGGNILVLLAFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTGKRDLLPGQCAVQFLKDPIFNTALIIGYYWTTLIVLFVLYAGIYKTAYDMQKRSEAKQRKMQSMVALSAGAMSGMAGHAAGIGVIEEKILKTKVELAGDQTDLDSACTTVIKRLSGSGQANPLAVATEEVEKMTPEQRRASAAKIQEEAKKREAAVDAEKSERSSSPAFDSDEESSVNQAQQLITQQKLNNMRKRSSIGLVFGAQAALLATRGKGNLQKSTTNSKSIEAMHQYHHHQQHHHNQSPLQRAQSKEEMRSLHHHQNQQQPHHQHHQNQPNPPLDRPKRTSCSTLSQIAEHDRLVDLSAPPTLLNTSDPLSPVDLAPIEVPSDQVHQGLVQTILPPPDAFQCPTPLSDDYSDRPFGNSSGNSELALTYDLMTNSELRYMDESSAMLASVTANSTTSPNDSVQGKPPVLPPPPPARRNPPKSNLNQSLSQTPSQNQSPSQSLSLNLNPNHNQSQSQSIEEAVAIEKRLLVSYTGIEDFAKVRRESCIEAICLLDVPGKLAADCPHRRASSPMETSSKDAILYSPMPPMPLSPKVKTSTPQTGTPQSAAGVTPPVPLERIEERETSDSNTNKMPSTSGTTSSTGGVGGGGEQDGVGATKKNAGDDDANREEKSLAASRNSSKRAFIHSIGKHFKSKKALPLILGVGGRQKSKSENRARKAFRTISFILGCFVACWTPYHVLALVEGFCRHPPCINEHLYMFSYFLCYANSPMNPFCYALANQQFKKTFTRILKGDLHMT
Protein: Double-stranded RNA-specific adenosine deaminase adr-2 (DRADA) (EC 3.5.4.37) (Q22618)
Organism: Caenorhabditis elegans
Function: Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. Acts primarily on non-coding regions of protein-coding genes including introns and untranslated regions (UTR). Required for normal chemotaxis. Edits the 3' UTR of clec-41 which is required for normal clec-41 expression and for chemotaxis. Plays a role in determining lifespan. Not required for RNA interference. Likely to play a role in determining whether a dsRNA enters the RNAi pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:18780728}. Cytoplasm {ECO:0000269|PubMed:18780728}.
Interaction partners:
- Adr-2-binding protein 1
- DRBM domain-containing protein
- Cubilin
- Protein kinase domain-containing protein
- Piwi domain-containing protein
- A-to-I RNA editing regulator adr-1
- adenosine deaminase
- R151.8A protein
- CABIT domain-containing protein
Sequence:
MSVEEGMEVELKSEKMDLDDNIPDFVKETVERSGKNPMSLFSELYVHMTGNTPVFDFYNRNQPNGSMKFICVVILNGERIEGNVKSKKKEAKVSCSLKGLEVVLKHVSEYVVPAVKFEEKTTFFEMLREHTYAKFYELCKNNALIYGFEKVIASVFLKINGNLQIIALSTGNKGLRGDKIVNDGTALIDCHAEILARRGLLRFLYSEVLKFSTEPPNSIFTKGKNALVLKPGISFHLFINTAPCGVARIDKKLKPGTSDDLQNSSRLRFKIDKGMGTVLGGASEFEAPQTFDGIMMGERMRTMSCSDKLLRANVLGVQGAILSHFIDPIYYSSIAVAELNNADRLRKAVYSRAATFKPPAPFHVQDVEIGECQVEDTEQSTSAAARSTISSMNWNLADGNTEVVRTSDGMVHDKDMSGADITTPSRLCKKNMAELMITICTLTKTSVDYPISYEELKAGSQEYAAAKKSFITWLRQKDLGIWQRKPREFQMFTIN
Protein: Xylulose kinase (Xylulokinase) (EC 2.7.1.17) (P42826)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Xylulose kinase necessary for growth in culture media with D-xylulose as the solecarbon source.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- D-xylulose reductase
- Ribulose-phosphate 3-epimerase
- Sorbitol dehydrogenase 2
- Sorbitol dehydrogenase 1
- NADPH-dependent aldose reductase GRE3
- Transketolase 1
- Transaldolase
- Transketolase 2
- Transaldolase NQM1
- 4-nitrophenylphosphatase
Sequence:
MLCSVIQRQTREVSNTMSLDSYYLGFDLSTQQLKCLAINQDLKIVHSETVEFEKDLPHYHTKKGVYIHGDTIECPVAMWLEALDLVLSKYREAKFPLNKVMAVSGSCQQHGSVYWSSQAESLLEQLNKKPEKDLLHYVSSVAFARQTAPNWQDHSTAKQCQEFEECIGGPEKMAQLTGSRAHFRFTGPQILKIAQLEPEAYEKTKTISLVSNFLTSILVGHLVELEEADACGMNLYDIRERKFSDELLHLIDSSSKDKTIRQKLMRAPMKNLIAGTICKYFIEKYGFNTNCKVSPMTGDNLATICSLPLRKNDVLVSLGTSTTVLLVTDKYHPSPNYHLFIHPTLPNHYMGMICYCNGSLARERIRDELNKERENNYEKTNDWTLFNQAVLDDSESSENELGVYFPLGEIVPSVKAINKRVIFNPKTGMIEREVAKFKDKRHDAKNIVESQALSCRVRISPLLSDSNASSQQRLNEDTIVKFDYDESPLRDYLNKRPERTFFVGGASKNDAIVKKFAQVIGATKGNFRLETPNSCALGGCYKAMWSLLYDSNKIAVPFDKFLNDNFPWHVMESISDVDNENWDRYNSKIVPLSELEKTLI
Protein: Dpr-interacting protein zeta, isoform C (M9MSH3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLPPSWHLIGALLVLAATAGDSTNKIILPQILNGGGGGGGVGTAQGKHPSGSKTVATGVVPNFGGAAGNGAGGGGPVAGSGTGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTASSGIYSTDTHWGENGINNNYAYGGPDSTRSIYAQDKNKTQNPLLANGNANEADAESNGARGHNPSMAIAWLFVVIATLLLTIRSAVGSSHSLSLC
Protein: TrwI protein (O50333)
Organism: Escherichia coli
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAFELFTPLFNKIDQTTATYVTDISSRAIAAITPVVSVGLTLGFITYGWLIIRGAVEMPVAEFLNRCLRIGIIVSIALAGGLYQGEIANAITTVPDELASALLGNPTEGASAAALVDQSAQQGFDRASEAFEEAGFFSSDGLLYGLFGIIIPAGYGPAGAIGGAFLLLAKIALALLAGLGPLFILALIWQPTHRFFDQWAQQVLNYGLLIVLFAAVFGLLMQIFGSYMADLRFDGAQNVAYAIGGSVILSIVSIVLLMQLPSIASGLAGGIGLGYMWELRSMRSGAGAAMRGGRAMARGARAAPGAARGAAVGAANMAKTVATGGAGVARAAAGYFRGRKAG
Protein: Bilobe protein, conserved (Q38A92)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNMISLNFTLYRFVCDKVTFSNIFAVDAESRRFPENSPFYCCWAIVPRQRAVSTVKAAEWSGCTPASYFKSHGNEIVLPFNNAVGTVDIEGDTNVITFNVRPYSNSNEPISVVAKGTLDPRPYVGRSNRNYAIKLRDVSGQTIGKLLFALEAREESGCVISTPLGIDGQPGVHTGLSNNLLNAVGVGASAGNLALRNRNENGRNGYGTVDGGKVQYDKREPYAQRDNSSFSNSVTPQAGSLEGMPMQAFNCLRAPTSTSATTECDPHSYVKLDLCIERIVVKDDSSGQENPVPLLLGANYYLKVRFGGGVSTTQSVECQDPRKITYKDHMTFIEDVCSNDRLRFSLWENGKQVAGFSLNPTKFRVDIGMQKEYAIPFRYYPTRQSAFLELTVQRMGEPSLEDVEKTIDSFRVVRGIPFGGMRFMDEQLQLRRSEGESSEHLNTKTIGTTSGHSTTNLSSHTPEKAVEKGQRPEKLCREECGKQHTPLRAEHSSPPVAAEKKDFGQPGHHQTKAKNGDRHDTHTNPAVTQLAPSERVGENITNSVNSSFIVKQVSPVRKGSSAKRHALLRRMTEEEVVPASAMRQYPGNDAPTSMKTVVRSMETTRSASPLRVTGAPRGDQRPRKLEDEYQSLTGGSKLLSMEDASQPRRNSPSTSPDQRVPDNAIDRERLVDSLLHRMNGRPGMNTTLMEEWMEWRHTCLSSRSSRSGSEGSAFCREDSVASLEIRSHAVSPRPTKSLSHAADMRPYTPVITRRAASDGRPPIPGR
Protein: TATA-box-binding protein 1 (EhTBP) (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit) (P52653)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Subcellular location: Nucleus.
Interaction partners:
- Bromodomain protein, putative
- TFIIB-type domain-containing protein
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 9
- TFIID subunit, putative
- Transcription initiation factor TFIID subunit 5, putative
- Uncharacterized protein
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 8
- DNA-directed RNA polymerase II subunit, putative
Sequence:
MSTPGDFSLSPFILGGAVDPRSMSQLGNICHADYMSTSTESQERSLNNPNDTHPEIVNVVSTFQLGVKLELRKIVQKARNAEYNPKRFAGAIMRISSPKSTALIFQTGKIVCTGTRSIEESKIASKKYAKIIKKIGYPIHYSNFNVQNIVGSCDVKFQIALRTLVDSYLAFCQYEPEVFPGLVYRMASPKVTLLVFSTGKVVLTGAKDEESLNLAYKNIYPILLANRKEDISNQ
Protein: S-nitrosomycothiol reductase MscR (O53533)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Metallo-beta-lactamase domain-containing protein
- Mycothione reductase
- S-adenosylmethionine-dependent methyltransferase Rv2258c
- Conserved protein
Sequence:
MSQTVRGVIARQKGEPVELVNIVVPDPGPGEAVVDVTACGVCHTDLTYREGGINDEYPFLLGHEAAGIIEAVGPGVTAVEPGDFVILNWRAVCGQCRACKRGRPRYCFDTFNAEQKMTLTDGTELTAALGIGAFADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAINTGGVTRDDTVAVIGCGGVGDAAIAGAALVGAKRIIAVDTDDTKLDWARTFGATHTVNAREVDVVQAIGGLTDGFGADVVIDAVGRPETYQQAFYARDLAGTVVLVGVPTPDMRLDMPLVDFFSHGGALKSSWYGDCLPESDFPTLIDLYLQGRLPLQRFVSERIGLEDVEEAFHKMHGGKVLRSVVML
Protein: Sp7 transcription factor (Q6IMK2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Runt-related transcription factor 2
- Nuclear factor of activated T-cells 1
- Integrin-binding sialoprotein
- Ribosomal oxygenase 1
- Sclerostin
- Catenin beta-1
- Tumor necrosis factor ligand superfamily member 11
- Homeobox protein DLX-5
- Homeobox protein DLX-2
- Osteocalcin
Sequence:
MASSLLEEEAHYGSSPLAMLTAACSKFGGSSPLRDSTALGKGGTKKPYTDLSAPKTMGDAYPAPFSSTNGLLSPAGSPPAPASGYANDYPPFPHSFPGPTGAQDPGLLVPKGHSSSDCLPSVYTSLDMSHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLSTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGAGKPPRGAGTGGSGGYAGSGAGRSTCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSVGEEEANQPPRSSTSPAPPEKAPGGSPEQSNLLEI