wanglab/gogpt-training-data huggingface dataset:
Protein: Shaven, isoform C (Q8IM96)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLIMDIQTSTHHIHGLGTHELQHRILHPHILHSTQEETLNTSTGQLEHDSQHLQQHHLTHHQQQDVSPTLHNLQNTRTGDSLSTTINTNQNQHGHQHLSGSNMYTSSQMEDKSKANKYDEYSSRTLSNISDANTTPSANNFITQSQGIEWITAMNDIQNGAEDSHSSQGSISGDGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSIYTPAIGPSIGCSSVVPGSDYAYNPAYTQYGGAYGSYGYGTGSGLINSSYYYESGQTQSPLTHDLRSPLVATRANSLASAASPGSGSACTKSESSDIFLA
Protein: FAST kinase domain-containing protein 2, mitochondrial (Q922E6)
Organism: Mus musculus (Mouse)
Function: Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. May play a role in mitochondrial apoptosis.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:Q9NYY8}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250|UniProtKB:Q9NYY8}. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. {ECO:0000250|UniProtKB:Q9NYY8}.
Interaction partners:
- Neugrin
- Pseudouridylate synthase RPUSD4, mitochondrial
- Mitochondrial mRNA pseudouridine synthase Rpusd3
- Pentatricopeptide repeat-containing protein 1
- Pseudouridylate synthase TRUB2, mitochondrial
- Transcription termination factor 3, mitochondrial
- Probable ATP-dependent RNA helicase DDX28
- Fas-activated serine/threonine kinase
- FAST kinase domain-containing protein 1
- G-rich sequence factor 1
Sequence:
MNSKARSLLWTIRRFSTLLPRSRALRIDPLGTCRPEVIHSKWNPRNHRLNVFDEGLQPSVRYLFQDIFISKSVDGCIQTKGISHSAVFKPDRLLCPRRLSFDAKHSFVSDGTSDHDLKKINFHHTSSEDVFTKKVRPTPVNYKKLAQECNSLSDVLDTFSKAPTFPGSNYFLAMWIIAKRISEDKRRFERQLMFSHPAFNQLCEQMMREAKIMHYDHLLFSLNAIVKLGIPQNTLMVQTLLRTIQERINECDERCLSILSTALVSMEPCMNVNALRAGLRILVDQQVWNIKHVFTLQTVMKCIGKDAPSALKKKLEMKALKELGRFSILNSQHMFEVLAAMDLRSVVLLNECSKVVIDNVHGCPFKVLISILQSCRDLRYQNEDLFKSIAEYVATTFDIWKLKQVIFFLLLFETLGFRPPGLMDKLMEKVVQEPGSLNVKNIVSILHVYSSLNHVHKIHNREFLEALASALTGCLHHISSESLLNAVHSFCMMNYFPLAPINQLIKENIINELLTSGDTEKNIHKLHVLNTCLKLDESTYKSVHIPLPQLPLSASQPNEKLAEVLSRLLEGEGRFSRNVPLPHNYHIDFEIRMDTNRTQVFSFSDVDASSATNMQRVAVLCVPKSVYCLNSCHPRGLMAMKIRHLNVMGFHVILIHNWELKKLKMEDAVTFVRKKIYSDEVLPTADTTV
Protein: Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein) (Q8WZA0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLSANAGAILSQFEKVSTDLGSGDKILALASFEVEKTKK
Protein: Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (Q9QWF0)
Organism: Mus musculus (Mouse)
Function: Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q13111}. Note=DNA replication foci. {ECO:0000250|UniProtKB:Q13111}.
Interaction partners:
- Chromatin assembly factor 1 subunit B
- Histone-binding protein RBBP4
- Histone chaperone ASF1B
- Chromobox protein homolog 5
- Histone chaperone ASF1A
- DNA replication licensing factor MCM5
- DNA replication licensing factor MCM2
- DNA replication licensing factor MCM3
- DNA replication licensing factor MCM4
- Chromobox protein homolog 1
Sequence:
MLEEPEAATRTAAAVDCKDRPGFPVKRLIQARLPFKRLNLVPKEKVEEDTSPKAAVESKVPDLQLSLGTFESQCHTGSHVGLSTKLVGGQGPIDSFLRATIKPVPSVVIIDLTENCSDIPDSPEGHSELSPDTAGVVTTVEGAAKQQEHSAAELCLLETPSDITCHMEEEPGSPGDPKRTGDCQAGSLQSCPELTPGSRTCPTKELSSWSKAGDLLFIEKVPVVVLEDILATKPSIASLPMMSLDRSVTSESEILESCPEDDSILSHSSTNSSSPTSSPEGPSTPPEHRGGRSSPSTPACRVAKNFVKGSTEKGRSKLHRDREQQREEKEKLREEIRRAKEEARKKKEEEKELKEKERREKREKDEKEKAEKQRLKEEKRKERQEALEAKLEEKRKKEEEKRLREEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRCRAALDQDLCDQLDQLLQQQSVASTFLSDLKSRLPLRSGPTRVCGHDTDIMNRDVVIVESSKVDGVSERKKFGRMKLLQFSENHRPAYWGTWNKKTAIIRPRNPWAQDKDLLDYEVDSDDEWEEEEPGESLSHSEGDEDDDVGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVHQKLKAKEWDELLAKGKRFRVLQPVHVGCVWASEAANCTSSDLKLLQQFTACLLDVASPDEPEPGASRREKRDQHILAQLLPLLHGNVNGSKVIIHEFQEQCRRGLLTLPSPTPHLQMPNLEDAVAVPSKARLKRLISENSAYEKRPNFRMCWYVHPEVLKSFGQECLPVPCQWTYITTMPSAPREDSGSASTEGPGQSTPMLLKRKPAATMCITQFMKKRRYDGQVGSGDMDGFQADTEEDEEDDTDCMIIDVPDVGSDVSEAPIPAPTLCK
Protein: Geranylgeranyl pyrophosphate synthase (EC 2.5.1.29) (Q1G9H4)
Organism: Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14)
Interaction partners:
- Isoprenyl transferase
- diphosphomevalonate decarboxylase
- Exodeoxyribonuclease 7 large subunit
- Exodeoxyribonuclease 7 small subunit
- Isopentenyl-diphosphate delta-isomerase
- Putative RNA methylase
- Bifunctional protein FolD
- DNA repair protein RecN
- Elongation factor P
- Transcription antitermination protein NusB
Sequence:
MTTFKEFQAKYTPIINDFLEGQLAKESDDPRFAEIMAYSVMAGGKRLRPLLFLATLDALGVEITEKEVQAACGIELIHTYSLIHDDLPAMDNDDYRRGELTSHKKWGEAEAILAGDALQPLGIQWIAQAEHNWKLVEIITEAVGPKGMVAGQYLDIDTTNNEDSSEEVIDHMEWLKTGCLILASVQMATALAACPDQQAQKYLAFAKHFGRSYQLYDDLVDIVESQEEAGKATHKDQEVGKNNSLTMLGAEATRNELKQLIEKGKADLAGEKAEVLLGFLDLYQKVL
Protein: RNA helicase (EC 3.6.4.13) (A0A0G2K0E0)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Ribosome production factor 2 homolog
- CCAAT/enhancer-binding protein zeta
- Ribosome biogenesis protein BOP1
- WD repeat-containing protein 74
- Pescadillo homolog
- EBNA1 binding protein 2
- ATP-dependent RNA helicase
- GTP-binding protein 4
- ATP-dependent RNA helicase DDX1
- Nucleolar protein 58
Sequence:
MEDQEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHKKATGPVMEQAVRGLVLVPTKELARQAQSMIQQLASYCARDVRVANVSAAEDSASQRAVLMEKPDVVVGTPSRILNHLQQKNLKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLPRIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATDAEILGPQVKAKRQGRGSKGDKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPTEQSSLGKIEELLSGEGQAPILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGNVPDYLVPAALRGLVHPRKKRRKMPFSRKAKKVKTQNPLRDFKHRGKKPKPTAKPS
Protein: Probable G-protein coupled receptor 174 (Q3U507)
Organism: Mus musculus (Mouse)
Function: Putative receptor for purines coupled to G-proteins.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MTDNFTCNKTDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIIGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPIRNVNLAQSVAMITIGEVVGFVTPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALKMILTCAGVFLVCFVPYHFSFPLDFLVKSNEIKSCFARRVILIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQDLPDNIQLHTKSYKIASNHATSTVAAELC
Protein: protein disulfide-isomerase (EC 5.3.4.1) (Q86UY0)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
Sequence:
MTQSVDSNRGNRNEKRCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAKDEL
Protein: LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) (O60663)
Organism: Homo sapiens (Human)
Function: Transcription factor involved in the regulation of podocyte-expressed genes. Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- LIM domain-binding protein 1
- Homeobox protein Nkx-2.2
- Paired box protein Pax-2
- Homeobox protein Meis2
- Pre-B-cell leukemia transcription factor 3
- Single-stranded DNA-binding protein 3
- Putative nucleotidyltransferase MAB21L1
- Isopentenyl-diphosphate delta-isomerase 2
- Pre-B-cell leukemia transcription factor 1
- Single-stranded DNA-binding protein 2
Sequence:
MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGDHMNPYGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS
Protein: Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) (P21954)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mitochondrial IDP1 may regulate flux through the tricarboxylic acid cycle and respiration. Its probably critical function is the production of NADPH.
Subcellular location: Mitochondrion.
Interaction partners:
- Aconitate hydratase, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Isocitrate dehydrogenase subunit 1, mitochondrial
- Isocitrate dehydrogenase subunit 2, mitochondrial
- Citrate synthase 3, mitochondrial
- Citrate synthase, mitochondrial
- Citrate synthase, peroxisomal
- Glutamate synthase
- NADP-specific glutamate dehydrogenase 1
- NAD-specific glutamate dehydrogenase
Sequence:
MSMLSRRLFSTSRLAAFSKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQDAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVIPRIPRLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDYKGSGVAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGNNERSAYVTTEEFLDAVEKRLQKEIKSIE
Protein: Endoplasmic reticulum membrane sensor NFE2L1 (Nuclear factor erythroid 2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (F5H1B7)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004648}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004643}; Single-pass type III membrane protein {ECO:0000256|ARBA:ARBA00004643}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTRLDRSSHSGGGHAKGSRPLNSLLAGHRVAQPASAPGSRASVQDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYSAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFLLFSPEVESLPVASSSTLLPLAPSNSTSLNSTFGSTNLTGLFFPPQLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPAQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSALKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK
Protein: Endophilin-B2 (SH3 domain-containing GRB2-like protein B2) (B7ZC38)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS
Protein: UPF0047 protein Rv2556c (P9WFP9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Alanine--tRNA ligase
- Putative pre-16S rRNA nuclease
- Endolytic murein transglycosylase
- Probable shikimate 5-dehydrogenase AroE
- Prepilin type IV endopeptidase peptidase domain-containing protein
Sequence:
MDTDVLDVDTARRRIVDLTDAVRAFCTAHDDGLCNVFVPHATAGVAIIETGAGSDEDLVDTLVRLLPRDDRYRHAHGSYGHGADHLLPAFVAPSVTVPVSGGQPLLGTWQSIVLVDLNQDNPRRSVRLSFVEG
Protein: Branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein, putative (Q5LQF6)
Organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Interaction partners:
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, permease protein
- Branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein
- Branched-chain amino acid ABC transporter, periplasmic substrate-binding protein
- Branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid binding protein
- Branched-chain amino acid ABC transporter, periplasmic substrate-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- Branched-chain amino acid ABC transporter, ATP-binding protein
- ABC transporter, periplasmic substrate-binding protein, putative
- Branched-chain amino acid ABC transporter, periplasmic substrate-binding protein
Sequence:
MTKELQHTQTRRGFLKSAGMATGSAAMLAGLNSAAQAQSSDPVVIGCPAPLTGIVAADGIEFQRGIQMAADEINAVGGILGRPIELVFADTQSKGVDVVIQSAQRLIDRDNASALIAGYNLENGTALHDVAADAGVIAMHANTVAVHDEMVKSDPDRYWGTFQYDPPETLYGGGFLKFLKDIEDNGEFSRPNNKIAIITGPGIYSVNIANAIRDGAGEYGYDVSLFETVAIPVSDWGPTLAKLRADPPAVIVVTHFYPQDQALFMNQFMTDPTNSLVYLQYGASLAAFRDIAGDNSVGVTYATVLGTLQDEMGDAFAKAYKERYGDLSSTASGCQTYSALYAYSIAAALAGGPGAPYDDVQNKAVADRLRSLIFRGPVGTMRFHADTQSAWSYPTETNDPSLGMPHIFSQIFDKAEDGVLIAPAPYKKAGFKMPPWMKG
Protein: Mitogen-activated protein kinase kinase 4 (AtMKK4) (MAP kinase kinase 4) (EC 2.7.12.2) (O80397)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the morphology of plant organs. MKK4 and MKK5 participate in the regulation of floral organ abscission. Mediates osmotic-stress response via its regulation of MPK3 activity. Target of the Pseudomonas syringae type III effector HopF2.
Subcellular location: Cytoplasm. Nucleus. Plastid, chloroplast stroma.
Interaction partners:
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 6
- Mitogen-activated protein kinase kinase kinase 1
- Mitogen-activated protein kinase kinase kinase YODA
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase kinase kinase ANP1
- Mitogen-activated protein kinase kinase 5
- Mitogen-activated protein kinase kinase kinase 2
- Probable WRKY transcription factor 33
- Transcription factor SPEECHLESS
Sequence:
MRPIQSPPGVSVPVKSRPRRRPDLTLPLPQRDVSLAVPLPLPPTSGGSGGSSGSAPSSGGSASSTNTNSSIEAKNYSDLVRGNRIGSGAGGTVYKVIHRPSSRLYALKVIYGNHEETVRRQICREIEILRDVNHPNVVKCHEMFDQNGEIQVLLEFMDKGSLEGAHVWKEQQLADLSRQILSGLAYLHSRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNQGKYDGYAGDIWSLGVSILEFYLGRFPFPVSRQGDWASLMCAICMSQPPEAPATASPEFRHFISCCLQREPGKRRSAMQLLQHPFILRASPSQNRSPQNLHQLLPPPRPLSSSSSPTT
Protein: Glucose transporter GLUT4 (Q6Q244)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
SEELWPVLVGVTVLPTVLQMALLPFCPESPRFLYIIRCQEHHAKSGLRRLTGRQEVGDMLAEMKEEKRRMDMERKVSIAELFRSPMYRQ
Protein: Probable short-chain type dehydrogenase/reductase (O53863)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
Sequence:
MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHSVMCDVRHREEVTHLADEAFRLLGHVDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAKYGVVGLAETLAREVTADGIGVSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILANRLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH
Protein: Cysteine proteinase 2 (EhCP2) (EC 3.4.22.35) (Histolysain) (Histolysin) (Q01958)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: Cysteine protease which degrades matrix proteins such as collagen, laminin and fibronectin and thus is involved in the destruction of human tissue. Can abolish adhesion. May play an important role in pathogenicity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11755183}; Peripheral membrane protein {ECO:0000269|PubMed:11755183}; Extracellular side {ECO:0000269|PubMed:11755183}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:11755183}. Secreted {ECO:0000269|PubMed:16979632}. Note=During phagocytosis, localizes to phagocytic vesicles. {ECO:0000269|PubMed:11755183}.
Interaction partners:
Sequence:
MFAFICLLAIASAIDFNTWASKNNKHFTAIEKLRRRAIFNMNAKFVDSFNKIGSFKLSVDGPFAAMTNEEYRTLLKSKRTTEENGQVKYLNIQAPESVDWRKEGKVTPIRDQAQCGSCYTFGSLAALEGRLLIEKGGDANTLDLSEEHMVQCTRDNGNNGCNGGLGSNVYDYIIEHGVAKESDYPYTGSDSTCKTNVKSFAKITGYTKVPRNNEAELKAALSQGLVDVSIDASSAKFQLYKSGAYTDTKCKNNYFALNHEVCAVGYGVVDGKECWIVRNSWGTGWGDKGYINMVIEGNTCGVATDPLYPTGVQYL
Protein: Retinaldehyde dehydrogenase 3 (RALDH-3) (RalDH3) (EC 1.2.1.36) (Aldehyde dehydrogenase 6) (Aldehyde dehydrogenase family 1 member A3) (ALDH1A3) (P47895)
Organism: Homo sapiens (Human)
Function: NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid. Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde. Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9JHW9}.
Interaction partners:
- Retinol dehydrogenase 12
- Retinol dehydrogenase 10
- Cytochrome P450 26A1
- Cytochrome P450 26B1
- Cytochrome P450 26C1
- Short-chain dehydrogenase/reductase 3
- Cytochrome P450 1A1
- Retinol dehydrogenase 11
- Retinol dehydrogenase 5
- Aldehyde oxidase
Sequence:
MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP
Protein: Growth hormone secretagogue receptor type 1 (GH-releasing peptide receptor) (Ghrelin receptor) (C7G182)
Organism: Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MREGSAENRTGGESPLRLFPAPVLTGITVACVLLFVVGVLGNMMTMLVVSRFRDMRTTTNFYLSSMAFSDLLIFLCMPLDLFRLWQYRPWNFGDLLCKLFQFISESCTYSTILNITALSVERYVAICFPLRAKVIITKRKVKLVILILWAISFISAGPIFVLVGVEHENGTNPLSTNECRATEYAIRSGLLTIMVWISSIFFFLPVFCLTVLYSLIGRKLWRRKRKNIGPSTVIRDKNNKQTVKMLVVVVFAFILCWLPFHVGRYLFSKSFEAGSLEIAVISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAACRLFGLKTLPKKRLSSTKQDSSRVWTEPTVAT
Protein: Glutamate decarboxylase 1 (GAD 1) (EC 4.1.1.15) (Q42521)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the conversion of glutamate to 4-aminobutanoate (GABA). The calmodulin-binding is calcium-dependent and it is proposed to directly or indirectly form a calcium regulated control of GABA biosynthesis.
Interaction partners:
- Gamma-aminobutyrate transaminase POP2, mitochondrial
- Glutamate dehydrogenase 2
- Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1, mitochondrial
- Glutamate dehydrogenase 1
- glutamate dehydrogenase
- Probable glutamate dehydrogenase 3
- Pantoate--beta-alanine ligase
- Glutamate synthase 1, chloroplastic
- Calmodulin-1
- Beta-ureidopropionase
Sequence:
MVLSHAVSESDVSVHSTFASRYVRTSLPRFKMPENSIPKEAAYQIINDELMLDGNPRLNLASFVTTWMEPECDKLIMSSINKNYVDMDEYPVTTELQNRCVNMIAHLFNAPLEEAETAVGVGTVGSSEAIMLAGLAFKRKWQNKRKAEGKPVDKPNIVTGANVQVCWEKFARYFEVELKEVKLSEGYYVMDPQQAVDMVDENTICVAAILGSTLNGEFEDVKLLNDLLVEKNKETGWDTPIHVDAASGGFIAPFLYPELEWDFRLPLVKSINVSGHKYGLVYAGIGWVIWRNKEDLPEELIFHINYLGADQPTFTLNFSKGSSQVIAQYYQLIRLGHEGYRNVMENCRENMIVLREGLEKTERFNIVSKDEGVPLVAFSLKDSSCHTEFEISDMLRRYGWIVPAYTMPPNAQHITVLRVVIREDFSRTLAERLVIDIEKVMRELDELPSRVIHKISLGQEKSESNSDNLMVTVKKSDIDKQRDIITGWKKFVADRKKTSGIC
Protein: Glycine betaine/proline betaine-binding periplasmic protein (GBBP) (P0AFM2)
Organism: Escherichia coli (strain K12)
Function: Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity.
Subcellular location: Periplasm {ECO:0000269|PubMed:3305496, ECO:0000269|PubMed:7898450}.
Interaction partners:
- Glycine betaine/proline betaine transport system permease protein ProW
- Glycine betaine/proline betaine transport system ATP-binding protein ProV
- Proline/betaine transporter
- Glycine betaine uptake system permease protein YehY
- Glycine betaine-binding protein YehZ
- Glycine betaine uptake system permease protein YehW
Sequence:
MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQTLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKKFYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPGWGCEGAINHQLAAYELTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNELKPGKDVVWLQVPFSALPGDKNADTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLFAIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDGWVNEALAAQK
Protein: Protein cuti-1 (Cuticle and epithelial integrity protein 1) (O02051)
Organism: Caenorhabditis elegans
Function: Involved in cuticle formation and ensures cuticle shedding during larval development. Plays a role in maintaining the hypodermis. In association with vps-39, may play a role in vesicle tethering.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:19357781}.
Interaction partners:
- Tetraspanin-15
- long-chain-fatty-acid--CoA ligase
Sequence:
MPNDRVAPLPPNFVYSPHDKFYYAPATCNSMHYTTASYISAFIEFLVMGTGAICFYVMSHKSDSIGKWLFYIQAGITVLSLLTSALMAFGLWKENPQMLGSKLKFIEFIICFLLIWAVISIVCMAFGIQFTRQVFGIFGKVHRIEQDYGPIWPFNIAVVSFFTAAIAIWTRIIIQGAADYLYDKAYFADKQNVELRESSKTR
Protein: Uncharacterized protein (Q38B06)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSSRVTSANHSMESCNTSLQRSGLNMSVGDTRSIVLALQTLQEKIRRLEQDRNHHQDQYEKALQAHEAYKQDMEHQLEQERSHHRRREKELHEMVQRATEEKTRLQSTLEESRKDLGTFRTELEEMLMKECDASKKRESALNSEMERLRHELEEQQKKHRTLLASIEELKAEKEAAIDTNHHLEQAIQELMRRCGTGSVDNSRMTDCDVTRLTNGSCRRNSRKPRRSNAFVGPVRGRLQEARHLVNISGHSAERRRASVGLAGNTRRTYRDPTYSSIQRDARRTSAGRALELGLNNSYHVRPVSRGRAATPVNQSHFDSVEGGLRSGAMKEVYEELQEELKSLHQQYKDTVERAAAEEISPEVVTAALNRISTLMDRKTDQIRLIKEAQRDMANAGVTVTDVPVPRPISSDRRRNPTPVGADKTTQRSLIVNELRSLYSQHR