wanglab/gogpt-training-data huggingface dataset:
Protein: UDP-rhamnose/UDP-galactose transporter 6 (UDP-Rha/UDP-Gal transporter 6) (Bi-functional UDP-rhamnose/UDP-galactose transporter) (Q9FDZ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Nucleotide-sugar transporter that transports UDP-rhamnose or UDP-galactose and UMP in a strict counter-exchange mode.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:25053812}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- DNAJ heat shock N-terminal domain-containing protein
- U6 small nuclear RNA
Sequence:
MAPVSKADKKAAVDAAAWMFNVVTSVGIIIVNKALMATYGYSFATTLTGLHFATTTLMTLVLRCLGYIQPSHLPFTELLRFILFANFSIVGMNVSLMWNSVGFYQIAKLSMIPVSCLLEMVFDKIRYSRDTKLSIGLVLVGVGVCTVTDVSVNTKGFVAAFVAVWSTALQQYYVHYLQRKYSLNSFNLLGHTAPAQAATLLVVGPFLDYWLTEKRVDMYDYNLVSVLFITLSCTIAIGTNLSQFICIGRFTAVSFQVLGHMKTILVLIMGFFFFGREGLNLHVVVGMIIAVLGMIWYGNASSKPGGKERRNYSLPTTRQQKLGAASDSDDNEDKA
Protein: Protein disulfide-isomerase 2 (EC 5.3.4.1) (PDI 1) (Prolyl 4-hydroxylase subunit beta-2) (Q17770)
Organism: Caenorhabditis elegans
Function: Involved in cuticle formation. May play a role in the unfolded protein response.
Subcellular location: Endoplasmic reticulum lumen.
Interaction partners:
- Endoplasmic reticulum oxidoreductin-1
- Fe2OG dioxygenase domain-containing protein
- Prolyl 4-hydroxylase subunit alpha-1
- Microsomal triglyceride transfer protein homolog
- Heat shock 70 kDa protein C
- Prolyl 4-hydroxylase subunit alpha-2
- Calreticulin
- Protein disulfide-isomerase A6 homolog
- Endoplasmin homolog
- Fe2OG dioxygenase domain-containing protein
Sequence:
MFRLVGLFFLVLGASAAVIEEEENVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIGYFKDTTSDDAKTFLEVAAGIDDVPFGISTEDAVKSEIELKGEGIVLFKKFDDGRVAFDEKLTQDGLKTWIQANRLALVSEFTQETASVIFGGEIKSHNLLFVSKESSEFAKLEQEFKNAAKQFKGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFEEITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEGAGASEEEKAEEEADEEGHTEL
Protein: Glutaryl-CoA dehydrogenase, mitochondrial (EC 1.3.8.6) (K7ES74)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}.
Interaction partners:
Sequence:
MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGSSDSPASTPLVAGITGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTASK
Protein: Glutamate dehydrogenase 2, mitochondrial (GDH 2) (EC 1.4.1.3) (P49448)
Organism: Homo sapiens (Human)
Function: Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:22709669}.
Interaction partners:
- Glutamine synthetase
- Glutamate dehydrogenase 1, mitochondrial
- Delta-1-pyrroline-5-carboxylate synthase
- Pyruvate carboxylase, mitochondrial
- Glutaminase kidney isoform, mitochondrial
- Glutaminase liver isoform, mitochondrial
- Aspartate aminotransferase, cytoplasmic
- Putative aspartate aminotransferase, cytoplasmic 2
- Carbamoyl-phosphate synthase, mitochondrial
- Aspartate aminotransferase, mitochondrial
Sequence:
MYRYLAKALLPSRAGPAALGSAANHSAALLGRGRGQPAAASQPGLALAARRHYSELVADREDDPNFFKMVEGFFDRGASIVEDKLVKDLRTQESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTMELAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEVDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLSVQESLERKFGKHGGTIPIVPTAEFQDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVNAIEKVFKVYSEAGVTFT
Protein: RNA editing complex protein MP24 (Q86MW0)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MRVRSLLLCTRRDPLQRAVDVAYASGMLLGSGSSRGTTHFSETTAFRSSNFAADLRGGRVGLAGDGGTKCDDRNGELVRGRIQFASRCAEGPFVGASPTVTSCAHIEGVVRQVECGYVGGDRVLQFIIEVEEVPASGGTPMRLPLAVRWRPGSEVAQNRMDEWQKEMERLVGPRVLASGRLQVEECFDSGSRRLYKIPSLVLPATSTVEMISLQELEC
Protein: Cationic amino acid transporter 8 (Apicomplexan amino acid transporter 8) (PbApiAT8) (Novel putative transporter 1) (PbNPT1) (A0A509AE54)
Organism: Plasmodium berghei (strain Anka)
Function: Cationic amino acid transporter which transports L-arginine, L-lysine and, to a lesser extent, L-histidine and ornithine. Plays an essential role in gametogenesis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21752110, ECO:0000269|PubMed:28205520}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Zinc finger protein
- Merozoite surface protein 1
- Autophagy protein 5
- Protein transport protein USE1, putative
- Heptatricopeptide repeat-containing protein
- Fam-b protein
Sequence:
MNESNCTKIVNFLKGMRLKTNPNLPGAKQKTPLNIHRFYLLLIIIIYTATSACIYFDWTSIRNLLLNVGKYEHLNISKYADITLSPQYKKINNLYPMTLAIHFTMSVFCGFLYDHIGPKFTAIIGQGFNILSWIFLSIDTTKIDTTLIGFIFLGLGADTAFIPILTVSNLFPDISTFIMTVIGAAASLSYAVPATLNFVYKKYPHFPFYYICYGYIFIILIPCLLVATFLLPMKPFKGLDYYLENDQESDSKNKEQISYTDNDVEMQPSLIQNGNTNVSNNVNKNKATKNIIEGENFHKQSILLFFKVLLSYPSICIIVYFILFNISTVFYGMVTDIYFSYNKSIINIINILMPISFIPCIIFGRFINKYGAAIIIIIMNAFSALMHLTALIKHQAAGLISAFLYMCAASIYTSQIYCFLLNAFPSVVFGKLLGITSLFGGMFSLFCEKLYDNISNSSGNKNDPTTISILLAISFIIMFLPLSILYTRNYEKNIESVNSEKNQIQA
Protein: MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1) (Q9BUB5)
Organism: Homo sapiens (Human)
Function: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Subcellular location: [Isoform 2]: Cytoplasm.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus.
Interaction partners:
- Mitogen-activated protein kinase 1
- Eukaryotic translation initiation factor 4 gamma 1
- Eukaryotic translation initiation factor 4E
- Mitogen-activated protein kinase 3
- MAP kinase-interacting serine/threonine-protein kinase 2
- Eukaryotic initiation factor 4A-II
- Eukaryotic initiation factor 4A-I
- Mitogen-activated protein kinase 14
- Eukaryotic translation initiation factor 4E type 2
- Eukaryotic translation initiation factor 4 gamma 2
Sequence:
MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
Protein: Kallikrein 1-related peptidase b1 (EC 3.4.21.35) (Glandular kallikrein K1) (mGK-1) (Tissue kallikrein-1) (P00755)
Organism: Mus musculus (Mouse)
Function: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Interaction partners:
- Formyl peptide receptor 2
Sequence:
MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWHVAVYRYKEYICGGVLLDANWVLTAAHCYYEKNNVWLGKNNLYQDEPSAQHRLVSKSFLHPCYNMSLHRNRIQNPQDDYSYDLMLLRLSKPADITDVVKPIALPTEEPKLGSTCLASGWGSIIPVKFQYAKDLQCVNLKLLPNEDCDKAYVQKVTDVMLCAGVKGGGKDTCKGDSGGPLICDGVLQGLTSWGYNPCGEPKKPGVYTKLIKFTSWIKDTLAQNP
Protein: Clathrin light chain B (Lcb) (P04975)
Organism: Bos taurus (Bovine)
Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular location: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Interaction partners:
- Clathrin heavy chain 1
- AP-1 complex subunit beta-1
- Cyclin-G-associated kinase
- Epidermal growth factor receptor substrate 15
- Huntingtin-interacting protein 1-related protein
- Epsin 1
- AP-2 complex subunit alpha
- Clathrin light chain A
- SH3-containing GRB2-like protein 3-interacting protein 1
- Epsin 3
Sequence:
MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSQGGLAQPGPASGASEDMGATVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVMEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
Protein: BCH domain-containing Cdc42GAP-like protein (Q8IZM6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGSLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
Protein: T-complex protein 11-like protein 1 (Q9NUJ3)
Organism: Homo sapiens (Human)
Interaction partners:
- Tetratricopeptide repeat protein 5
- DEP domain-containing protein 7
Sequence:
MSENLDKSNVNEAGKSKSNDSEEGLEDAVEGADEALQKAIKSDSSSPQRVQRPHSSPPRFVTVEELLETARGVTNMALAHEIVVNGDFQIKPVELPENSLKKRVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLKDVLTTIGEKVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKILVRS
Protein: Uncharacterized protein (O53179)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable molybdenum cofactor guanylyltransferase
- 2-oxoglutarate oxidoreductase subunit KorB
- 2-oxoglutarate oxidoreductase subunit KorA
Sequence:
MAFRDILVLFSMKTLLTLAMAAASSTALTTVGVSGARLITYCVGVEDI
Protein: Myosin heavy chain-like protein (F4K210)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Vesicle-fusing ATPase
- Serine/threonine-protein kinase TOR
- Eukaryotic translation initiation factor 2 subunit beta
- Protein MODIFIER OF SNC1 11
- THO complex subunit 4D
- protein-synthesizing GTPase
- Protein transport Sec1a
- Alpha-soluble NSF attachment protein 2
- Protein transport Sec1b
- Alpha-soluble NSF attachment protein 1
Sequence:
MSSNWGSSSRDSSGSSSRSDVDNSFDADELLQIGSRCMELRREKEMLRESQSQSVELVRRLELNANSLSESRLEDKRRIQMLEKELLNCYQEIDYLRDQVNFRSQEMNDLSEHVLDLEVRVTKSGKLEEEVNYLREELCSSKSEQLLLLQELESTETELQFSLFSVEKLEESVSSLTLESQCEIESIKLDIVALEQALFDAQKFQGESIQENDKLREIVKELRLNSREAEENAECLEKQNKELMERCVASERNIKDLRQSFRGRLESESEAPVNPDCFHDIIKKLEVFQDGKLRDKMEDMARQILQYKDLVKQLKDELKEEKLKAKEEAEDLTQEMAELRYEMTCLLEEECKRRACIEQASLQRIANLEAQIKREKNKSSTCLVPLPAV
Protein: Protein DDR2 (P89113)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May play an important role in the response of cells to diverse environmental stresses.
Interaction partners:
- 12 kDa heat shock protein
- Catalase T
- Aldehyde dehydrogenase [NAD
- Meiotic sister chromatid recombination protein 1
- Inactive diphosphatase DCS2
- Protein SIP18
- 6-phosphogluconolactonase 4
- Heat shock protein 26
- Protein HOR7
- Glutamate decarboxylase
Sequence:
MKVSQVFISAISVFGLATSVNAQNASNTTSNAAPALHAQNGQLLNAGVVGAAVGGALAFLI
Protein: Micronemal protein 6 (Q9XYH7)
Organism: Toxoplasma gondii
Function: Escorter protein required for import of MIC1 and MIC4 adhesins into the microneme.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, microneme membrane {ECO:0000269|PubMed:11157983, ECO:0000269|PubMed:11861763, ECO:0000269|PubMed:18818666, ECO:0000269|PubMed:28898199}; Single-pass type I membrane protein {ECO:0000269|PubMed:11157983, ECO:0000269|PubMed:11861763}. Secreted. Note=Released as soluble 35 kDa protein after proteolytic processing of the C-terminus (PubMed:11861763).
Interaction partners:
Sequence:
MRLFRCCAAAVVAAESLLWLKNGSPFFAFLPGNGEIADNCSGNPCGGTAAGTCINTPSGYDCRCEPGYVLGVENDQVTCMMPSGVPMANFVQLSETPAACSSNPCGPEAAGTCKETNSGYICRCNQGYRISLDGTGNVTCIVRQESGCEENGCGPPDAVQSCRRLTGTAGRLCVCKENFIATIDASAHITCKRVPPHYRKPPFEFGKGGHPVDSEPSKRQREDEGESREPESDSTEPGRDQERRTPLEESQEPEGSTPDSQQSRGGSGSDSTESEEQGKEREEGSGHAGAIAGGVIGGLLLLSAAGAGVAYMRKSGSGGGEEIEYERGIEAAEASEVEVLVDLDSKTWD
Protein: Desaturase 1, isoform A (Desaturase 1, isoform B) (Desaturase 1, isoform C (EC 1.14.19.-, EC 1.14.19.1)) (Desaturase 1, isoform D) (Desaturase 1, isoform E) (GH23546p) (Q7K4Y0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Very long chain fatty acid elongase F
- Fatty acid synthase
- Fatty acid synthase
- Acetyl-CoA carboxylase, isoform A
- Acetyl-coenzyme A synthetase
Sequence:
MPPNAQAGAQSISDSLIAAASAAADAGQSPTKLQEDSTGVLFECDVETTDGGLVKDITVMKKAEKRRLKLVWRNIIAFGYLHLAALYGAYLMVTSAKWQTCILAYFLYVISGLGITAGAHRLWAHRSYKAKWPLRVILVIFNTIAFQDAAYHWARDHRVHHKYSETDADPHNATRGFFFSHVGWLLCKKHPEVKAKGKGVDLSDLRADPILMFQKKYYMILMPIACFIIPTVVPMYAWGESFMNAWFVATMFRWCFILNVTWLVNSAAHKFGGRPYDKFINPSENISVAILAFGEGWHNYHHVFPWDYKTAEFGKYSLNFTTAFIDFFAKIGWAYDLKTVSTDIIKKRVKRTGDGTHATWGWGDVDQPKEEIEDAVITHKKSE
Protein: GH10884p (Q8MRP0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEKMRLQQQQQLDGAHQLYAPVPSDYGREQEKLQQLMQELGSSAVEQDVRNALRAASGDVGLATRHYKIDQLARLGVAGRPQCEQALQQTNWSLEVAAELLLNAG
Protein: Transcription factor LBX1b (Ladybird homeobox 1b) (E7FDX5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor required for the development of hypaxial muscles.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|RuleBase:RU000682}.
Interaction partners:
Sequence:
MTTIKVVKICGAMESRGLNPLDHLPPPASSNKPLTPFSITDILSKPTVKRFHRIHRLPASDRVRQSITVSRQTLITQASPLCALQELASKTFKGLELGVLQAAEGKDGLKLFGQRDSPKKRRKSRTAFTNHQLYELEKRFLHQKYLSPADRDQIAHQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESVRSTGLVPLDKLAKLADLERCAAAGATGNPGPQCSPRLGHEYKTVHKLCLSPMSSLSDHTSQDCSEDEEVEIDVDV
Protein: Frizzled-5 (Fz-5) (mFz5) (Q9EQD0)
Organism: Mus musculus (Mouse)
Function: Receptor for Wnt proteins. Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro); the in vivo situation may be different since not all of these are known to be coexpressed. In neurons, activation of WNT7A promotes formation of synapses (By similarity). Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11520064, ECO:0000269|PubMed:20530549}; Multi-pass membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:11520064}; Multi-pass membrane protein {ECO:0000305}. Synapse {ECO:0000269|PubMed:20530549}. Perikaryon {ECO:0000250|UniProtKB:Q8CHL0}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8CHL0}. Cell projection, axon {ECO:0000250|UniProtKB:Q8CHL0}. Note=Localized at the plasma membrane and also found at the Golgi apparatus. {ECO:0000269|PubMed:11520064}.
Interaction partners:
- Protein Wnt-5a
- Protein Wnt-7a
- Low-density lipoprotein receptor-related protein 6
- Protein Wnt-11
- Proto-oncogene Wnt-1
- E3 ubiquitin-protein ligase RNF43
- Tyrosine-protein kinase RYK
- Protein Wnt-2
- Protein Wnt-3a
- BMP and activin membrane-bound inhibitor homolog
Sequence:
MARPDPSAPPSLLLLLLAQLVGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRRFTSRCCCSSRRGHKSGGAMAAGDYAEASAALTGRTGPPGPTAAYHKQVSLSHV
Protein: BRO1 domain-containing protein (Q389V7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAITVQLVLASTGHSLPMTVYQEETTPHTTCQLSSIPVLRSQKVFVSDLVLLIRNCRSASMADCHPSSEGWKYIECFDYTSLRPLRPNEAIADKQKLLVFTPLLLSEALLEQYSSTKEHSHRTKSKVDMEEERWLNLKQAIAALAVPLKLHREQMERQMDLCVKKVNETAPRFHAAKEGISHALEKIKDIKVFNDPDFSLIALVDASEIETAVEQGEVKLQRALRYLKEAQTMAPSVLDAISKEVELGNSIQTTSAWHSYKTTEQADGCSAVSALMLEVKRRVDAVRMILTDITKIGRKQSACSRYCDAVHCHVVQKENNLHQLPKGLEVAQRLMERRIVMRRAIHRLLAPLEDEHRSLQQHLRQFAGDWGDCLPKDLFGAVAAPLPPLYPVDDDVAQKMDRHFFDLEKDATEEFLLSVGAASVGPSEPCAALERRLREVEGELRLCRAALKATSREKNKLHTGGERPK
Protein: Myosin heavy chain-like protein, putative (RPG) (B3RH40)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Interaction partners:
- Protein VAPYRIN
- LysM domain receptor-like kinase 3
- Serine/threonine receptor-like kinase NFP
Sequence:
MAMSSDEAYHENERKLKDRKEKRKLCRSSRHSRDKFQERLDFKFYDFKALEIEKGWNQLFVSIICIETGETIAKSGKALVKNGECDWEDSMLSTIWISDYSLQDNQACLLKLLVAMGSPRFGTLGEATINLSSYIGQETFTASLPLIHHCSRGAILQVKIQCLTPRRNYRKDANSYGEEMSVGYDDVDSISNASDTTFSRTSISSSHCDQSENIFYLGELGSKRRGPLTTCSDHDIGSLESSFPSWIENLTQQSNVNGWKTNVQERQDSTCSKDGPYSLDDTSTLKHASSTSETSNLGTELQHDKMEDFGKVPHAGDTASTSSVCSSKDMLGAAQVTIELLHGEVKMWEEGSRKLMTDVDRLRKELQKKSKHKKDLEMELSASRKESSDLKEEIQRLTAMVKQNGSRNHRLQIEEMDNIIKELKDEINYQKGLNHDLEVKLNKTQESNIDIVSIFRNFEKKVEKQKMEIARLSRISIQFQDAENNSRGIEDSEEEDFSLSIEAMPQITRKEFCHSGFDFSTNENAIRCLHEGIELQEFRNMETERQVMREKQKSMQSTIQFLEKTLDEKDQKMQTATRHFMAQTLEENEAKWRNRLFEKEKQIANFEKKLYGSVNAFSNEILALTQKVQDLEAEFRKRHGESKEDLVVSGSFPSNSLLYHFDTAINITEAFLELYKQLLLSVENLKDQDSPKNESCFNMSELSKVAGKMDLKELTEGILCTIIQLTKLLESKAASFENEMNPQNEVRDLSELESSYDNQHAIFELEAEVAQLSEQISGLEAEVRHLNEEKALTHLALENSENIVIYLQAEIRRMENINEGQKIDLKIMGESIQKKWTEAQEECDFLKGSNLKLQATNENLIQVSKTLQMANGELRMRNFALHNRYTVLESKLGESQITFSDIMKFIEDLECKFTSILEEIALKEKTINVDLEALLQESIKQNERFTIEERFLTQMYMEKAAEVSNLQREVEHLTDQISDIYDRHNIIASKVVLDVYDLCADKAITESALQEEQEKVKLYEAKLDNLQAEYEITVHNYNKELAAMREKHETLMVNHEKTVVLLGSSKSNEEKLEGIVRGLEVELKDSELERLQATEEISELEVQLQKTVVLQNELFILKKSLYEAEIEYRRLEASYQMLSLEYDVLKAEKVSYMQRLLTTEKVTSEFEDCKRTKVELEDKIIRLEWDLTTKEASWRNNARLKYELAQVTRENGELFKEKDSLRQENEEYQKKVKSLEEKLKQKDDEQEQFIDKDRM
Protein: ATPase inhibitor mai-2, mitochondrial (B4LLX1)
Organism: Drosophila virilis (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- ATP synthase subunit gamma
- ATP synthase F
Sequence:
MFVVRRSTARLYPAGVQLAKMSGSQLGDLGSGAGQGGGGGGSIRAAGGAFGKLEAAREEEFFYKKQKEQLERLKNDQIHQAEFHHQQIKEHEEAIQRHKDFLNNLHK
Protein: Golgin A8 family member B (C9J1B5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLPVDGEERKSEGSDTEGDRTSPCAGPTSSATLKDLEVGGSGWRCSDPAGQPSNLLPQRGLGAPLPAETAHTQPSPNDRSLYLSPKSSSASSSLHARQSPCQEQAAVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEKKKLNTDLYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEWSLCAVAATQKKKPDGFSSRSKALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLLNRGQKERLREQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQVMETLTSAEKEPEAAVPASGTGGESSGLMDLLEEKADLREHVEKLELGFIQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQGGEEGEAAGAAGDGVAACGSYSEGHGKFLAAARNPAAEPSPGAPAPQELGAADKHGDLCEASLTNSVEPAQGEAREGSSQDNPTAQPVLQLLGEMQDHQEHPGLGSNCCVPCFCWAWLPRRRR
Protein: Dopamine beta-hydroxylase (EC 1.14.17.1) (Dopamine beta-monooxygenase) [Cleaved into: Soluble dopamine beta-hydroxylase] (Q64237)
Organism: Mus musculus (Mouse)
Function: Conversion of dopamine to noradrenaline.
Subcellular location: [Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000269|PubMed:7961964}. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen {ECO:0000269|PubMed:7961964}.; SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:7961964}; Single-pass type II membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane {ECO:0000269|PubMed:7961964}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Phenylethanolamine N-methyltransferase
- Aromatic-L-amino-acid decarboxylase
- Amine oxidase [flavin-containing] A
- Catechol O-methyltransferase
- Amine oxidase [flavin-containing] B
- Transmembrane O-methyltransferase homolog
- Tyrosine 3-monooxygenase
- Amine oxidase [copper-containing] 2
- Amine oxidase [copper-containing] 3
- Paired mesoderm homeobox protein 2A
Sequence:
MQAHLSHQPCWSSLPSPSVREAASMYGTAVAIFLVILVAALRGSEPPESPFPYHIPLDPEGILELSWNVSYVQEIIHFQLQVQGLRAGVLFGMSDRGEMENADLIMLWTDGDRAYFADAWSDRKGQIHLDSQQDYQLLQAQRTRDGLSLLFKRPFVTCDPKDYVIEDDTVHLVYGILEEPFQSLEAINTSGLHTGLQRVQLLKSEVPTPSMPEDVQTMDIRAPDILIPDNETTYWCYITELPPRFPRHHIIMYEAIVTEGNEALVHHMEVFQCAAESEDFPQFNGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPKEAGVPFGGPGSSPFLRLEVHYHNPRKIQGRQDSSGIRLHYTATLRRYDAGIMELGLVYTPLMAIPPQETAFVLTGYCTDKCTQMALQDSGIHIFASQLHTHLTGRKVVTVLARDGQERKVVNRDNHYSPHFQEIRMLKKVVTVYPGDVLITSCTYNTENKTLATVGGFGILEEMCVNYVHYYPQTELELCKSAVDDGFLQKYFHMVNRFSSEEVCTCPQASVPQQFSSVPWNSFNRDMLKALYDYAPISMHCNKTSAVRFPGEWNLQPLPKITSTLEEPTPRCPIRQTQSPANPTVPITTEADAE
Protein: ECF RNA polymerase sigma factor SigH (ECF sigma factor SigH) (Alternative RNA polymerase sigma factor SigH) (RNA polymerase sigma-H factor) (Sigma-H factor) (P9WGH9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RshA) until released. This sigma factor is involved in heat shock and oxidative stress responses; it positively regulates the expression of itself, sigE, sigB and a number of transcriptional regulators as well as other effectors of heat and oxidative stress, leading to direct and indirect control of up to 25% of the bacterial genome. Modulates expression of host genes for intercrine beta (chemokine CC) and apoptosis, altering the host immune response.
Interaction partners:
- DNA-directed RNA polymerase subunit beta
- Anti-sigma factor RshA
- DNA-directed RNA polymerase subunit beta'
- Uncharacterized protein
- ECF RNA polymerase sigma factor SigC
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit omega
- RNA polymerase sigma factor SigF
- RNA polymerase sigma factor SigB
- ECF RNA polymerase sigma factor SigD
Sequence:
MADIDGVTGSAGLQPGPSEETDEELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQLRGLLADVARDRGFARGEQAHEGVSS