wanglab/gogpt-training-data huggingface dataset:
Protein: Bacteriocin plantaricin ASM1 (C7G1H4)
Organism: Lactiplantibacillus plantarum (Lactobacillus plantarum)
Function: Bacteriocin with a narrow antibacterial spectrum. Antibacterial activity against the Gram-positive bacteria L.plantarun, L.pentosus, L.curvatus, L.lindneri, L.mesenteroides and E.faecilis. Lacks antibacterial activity against the Gram-positive bacteria L.brevis, L.sakei, L.lactis, P.acidilactici, B.subtilis, B.cereus, L.monocytogenes and S.aureus, and against the Gram-negative bacteria E.coli and S.typhimurium.
Subcellular location: Secreted {ECO:0000269|PubMed:19939484}.
Interaction partners:
Sequence:
MSKLVKTLTVDEISKIQTNGGKPAWCWYTLAMCGAGYDSGTCDYMYSHCFGVKHSSGGGGSYHC
Protein: Snf5p (A0A1D8PJZ6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- SWI/SNF catalytic subunit
- Swi1p
- Uncharacterized protein
- Arp9p
- Uncharacterized protein
- Actin-related protein 4
- Uncharacterized protein
- Chromatin structure-remodeling complex protein RSC8
- TATA-binding protein-associated factor
- Npl6p
Sequence:
MSFNQQSPNFSSSSGMNANTPQQQQQQRGGNLPALTPQMLQSLTPQQFQLFRSNPQFQEVMNQYMQKQQLLQQQQQQQQQQQQQGSPHLMNGIPNQPQANPQFRQQVVANQMPPNMVNVPGSQTIINQPIHGANIPINKVPSRRMSSIPGIPGGQNPPVGVPGGAGPLLAGVPGATPLVPGQGPACSVGGVLATGVPNPGGVPSTGTLNGAHGNAGLNTNLPPGVTPEILNKVPMKPMQNVKEWSEKLKQEGKDVPLDLKVYEDLIRKDKEFVGKLNKQLHDNKFIMENINRDIKSYNQIKQLRMNSIALSNKGQYNNSIWGEGYQGYGNGITNSSTKLFIPNRDLTDRIINERVMKNKNKPKHYVPIRLEFDQERDQFKLRDTFLWDLNEEIIKVEDFTAQLLEDYKFISKVHYETILSSIKEQIADYSQKPSKTMGELRIPIKIDITINNTQLTDQFEWDILNSQEGDAEEFSSYMCDELCLPGEFCTAIAHSIREQSQMYYKALNMVGYGFDGSPVHEDEIRNHLLPPLRLVSSDSGIVDDFFSILRNPSSLPDFSPTLGKLSQLEVERLDKEMERESRRKRRHNYNEDQQQGSGRGFTSRRIAAHAGRGNTIPDLSDIPKTFRTPAPSSILPGAVDMGVPEVYEYNEVLINRTQVRNPDYRPPTPIRVENELVDYNHDPIEGTFMVTIKLPV
Protein: Sorting nexin (M0R9L3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004180}.
Interaction partners:
- Dynamin-2
- Dynamin-1
- Actin nucleation-promoting factor WASL
- Sorting nexin-5
- Endophilin-A1
- Disintegrin and metalloproteinase domain-containing protein 15
- Amphiphysin
- Dynamin-3
- Myc box-dependent-interacting protein 1
- Synaptojanin-1
Sequence:
SATGTARVMYDFAAEPGNNELTVNEGEIITITNPNVGGGWLEGKNSKGEQGLVPTDYVEILPNDGKDPFSCGNSVADQAFLDSLSASTAQANSSSANSNNQVGGGSDPWSAWNAPRSGNWDSSDAWGTRTDGAGAQRNSSANNWDTGFGHPQAYQGPATGDDDEWDEDWDDPKSSSPYFKDSEPAEAGGIQRGNSRAGASSMKLPLNKFPGFAKPGMEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVVSESEVFQQFLNFRDEKEWKTGKRKAEKDELVGVMIFSTMEPEAPDLDLIEIEQKCDAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLAAVFSSSGYQGETDLNNAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGAHKGAIEKVKESDKLVATSKITPQDKQTMVKRVGTMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETVSAPLPTSLYAYVCVRGASMLRDLDHIELVSL
Protein: Pyridoxal phosphate binding protein (H0YBG2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
ILSLCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSVKLADKVNSSWQRKGSPERLKVMVQINTSGEEIYLFSVSFLEGKHGLPPSETIAIVEHINAKCPNLEFVGLMTIGSFGHDLSQGPNPDFQ
Protein: Proline-rich acidic protein 1 (Epididymis tissue protein Li 178) (Uterine-specific proline-rich acidic protein) (Q96NZ9)
Organism: Homo sapiens (Human)
Function: Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion (By similarity). Protects the gastrointestinal epithelium from irradiation-induced apoptosis (By similarity). May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas.
Subcellular location: Secreted {ECO:0000269|PubMed:14583459}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q80XD8}.
Interaction partners:
- CD48 antigen
Sequence:
MRRLLLVTSLVVVLLWEAGAVPAPKVPIKMQVKHWPSEQDPEKAWGARVVEPPEKDDQLVVLFPVQKPKLLTTEEKPRGQGRGPILPGTKAWMETEDTLGHVLSPEPDHDSLYHPPPEEDQGEERPRLWVMPNHQVLLGPEEDQDHIYHPQ
Protein: NHS actin remodeling regulator (A0A087WU78)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPKNAAVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREHRSRSDRREQRAAAPLSIAAPPLPAYPPAHSQRRREFKDRHFLTSHPPEDEDTDVMLGQRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRISGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTMFTPAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGESFVGDHERTPNDFSEAPSSPSAQDHQPTLGLACSQHLHSPQHKLSERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDASVFVTEQYNDHLDKVRGHRANSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLPHSSREMKLPLDFANTPSRMENANLPTKQEPSWINQSEQGIKEPQLDASDIPPFKDEVAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGTISLSKDLELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTILKSVNLRSINKSEEVKQKEENNTDLPYLEESTLTTAALSPSKIRPHTANKSVSRQYSTEDTILSFLDSSAVEMGPDKLHLEKNSTFDVKNRCDPETITSAGSSLLDSNVTKDQVRTETEPIPENTPTKNCAFPTEGFQRVSAARPNDLDGKIIQYGPGPDETLEQVQKAPSAGLEEVAQPESVDVITSQSDSPTRATDVSNQFKHQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASGISAKSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSITSPSSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGELTAESPQSTDDAHQGSQGAEALSPLSPCSPRVNAEGFSSKSFATSASARVGRSRAPPAASSSRYSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST
Protein: Bancal protein (Q7KHL0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKREMNDEGEGPQDQKRNRRSEETVRILIPSSIAGAVIGKGGQHIQKMRTQYKATVSVDDSQGPERTIQISADIESTLEIITEMLKYFEERDEDFDVRLLIHQSLAGCVIGKGGQKIKEIRDRIGCRFLKVFSNVAPQSTDRVVQTVGKQSQVIEAVREVITLTRDTPIKGAIHNYDPMNFDRVYADEYGGYGTGSGSTRPSQRGNNRNGGGAGGVAGGAAGGNGGGFNAGGARGNAGGRGGADRFGGAAGGAVAGAGMGQRDNPFINPWANGGGGDVDGFGNNAGGAGGFAGNSFGGGAGGPFGGGSFGNNGFGGGPSDFGGNSGNFGQAQGTNSLPSLGSFSQNQGGTSSLPSLGSFGQNPGGPGGLGNGLSGGANGGVGALGGANGAGGFNAVGGANGGPNGSPNAATNVPQGHDPNNSTQVTIPKELAGAIIGKGGGRIRRIRNESSAYITIDEPLPNSNDRIITISGTPKQIQMAQYLLQQSVHEEWQAKHLSGQGLEQLQQQ
Protein: Zinc finger CCCH domain-containing protein 46 (AtC3H46) (EC 3.1.-.-) (Q9SV09)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses RNA-binding and ribonuclease activities in vitro.
Interaction partners:
- Zinc finger CCCH domain-containing protein 28
- Zinc finger CCCH domain-containing protein 51
- Zinc finger CCCH domain-containing protein 62
- Zinc finger CCCH domain-containing protein 56
- Zinc finger CCCH domain-containing protein 59
- Zinc finger CCCH domain-containing protein 12
- Zinc finger CCCH domain-containing protein 1
- Splicing factor U2af small subunit B
- Splicing factor U2af small subunit A
- Zinc finger CCCH domain-containing protein 30
Sequence:
MDGYEATRIVLSRIQSLDPENASKIMGLLLLQDHGEKEMIRLAFGPETLVHSVIVKAKKELGLMNCSRSPWSHQDELISPKNNRGSSLNPASLPFYANGGRSSRDLTNDFELMDDMNSRSTDFLGSVHARSGSCVLDGLGYGGDSDLGFGGVPCSYFARGFCKNGASCRFVHSDGGADLVGSPSRIELLRSNSVPPRLAHHFMTRSSLPSFSTKGVNLQQNDVQRAAAALMIGDELQKLGRWRPERIDLSAMACPASRQIYLTFPADSRFREEDVSNYFSTFGPVQDVRIPYQQKRMFGFVTFVYPETVKSILAKGNPHFVCDSRVLVKPYKEKGKVPDKYRTNQTTERELSPTGLDSSPRDVLGGRGFYNNTQDVLWRSKFEEEILELQSRRLMNLQLLDVKKHFQLNSPTNIHSPNPFSQSLISPRPLSVIKREYDGGEKGKGSSKEGSDDDTMNLPERLEDSLPDSPFASPAHHLLLFADSADNNGSDLWSPSSDNDDNSTPSTLSDSFNSFNYQMPRLPAIGMLPGRGGPTCRVGI
Protein: Beta-H spectrin (Q7KQ57)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
NELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCE
Protein: Fgg protein (Fibrinogen gamma chain) (Fibrinogen, gamma polypeptide) (Q7ZVG7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Fibrinogen alpha chain
- Fibrinogen beta chain
- Prothrombin
- Protein AMBP
- Plasminogen
- Heparin cofactor 2 isoform X2, member 1)
- Antithrombin-III
- Alpha-2-HS-glycoprotein 1.
- Vitamin D-binding protein
- Alpha-2-HS-glycoprotein 2
Sequence:
MGSIMHVVASIVLLCTLTSAQRGDYSPSHDLCNPNDGFGTYCPTTCGVADYLQRYKPDMDKKLDDMEQDLEEIANLTRGAQDKVVYLKDSEAQAQKQSPDTYIKKSSNMLDDILRFEKSILAQEEQIYQLQSVLQANEKKITDLKQMSMQLDQMCKEPCKDTVEIQTVTGKDCQDIANKGGKVSGLYYVKPARAPEAFLVYCEIDSFGRGWTVLQRRRDGSVDFSKNWIQYKEGFGYLSPDDRTEFWLGNEKIHLLSVQSSVPYVLRIEMVDWEGNKKYADYATFKLGPEVDAYRLTYAYYFGGDAGDAFDGYDFGDDPSDKFYTSHNGMQFSTVDRDNDKFQGHCAQQDGSGWWMNRCHAAHLNGKYYQGGKYTEKDAESGYDNGIIWATWHSRWYSLKETTMKIIPINRIGATGGQESGSKQFGGIGDI
Protein: Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) (Q7KPV0)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU369121}.
Interaction partners:
- adenylate cyclase
- Guanine nucleotide-binding protein subunit beta-2
- G protein gamma domain-containing protein
- Guanine nucleotide-binding protein subunit beta-1
- Guanine nucleotide-binding protein subunit gamma
- Dopamine receptor 1
- G-protein coupled receptors family 1 profile domain-containing protein
- Muscarinic acetylcholine receptor gar-2
- adenylate cyclase
- Muscarinic acetylcholine receptor gar-3
Sequence:
MRLMGCVGAGADAEGREARKVNKQIEEQLAKDKQVMRATHRLLLLGAGESGKSTIVKQMRILHINGFNEAEKREKITDIRRNVRDAMQVILRAMDEIVPKVSLDDPSTAISRDYILRITNDPEDNYPSEFYDHILTCWKDKGVMACYERSSEYQLIDCAQYFLDKVDVVRQNNYDPSEQDILRCRVMTTGIFETKFEVDKVRFHMFDVGGQRDERRKWIQCFNDVTAIIFVCASSSYNLVLWEDNTQNRLRESLALFKNIWNNRWLKTISVILFLNKQDLLSEKIKAKRYLLESFFPEFEGYNLPNDAVFDNQEDKDVVRAKYFIRGEFLRISTANSDGRHHCYPHFTCAVDTENIRRVFNDCRDIIQRIHLRQYELL
Protein: Septin (J3KSZ7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MDRSLGWQGNSVPEDRTEAGDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
Protein: Dynein axonemal intermediate chain 4 (WD repeat-containing protein 78) (Q8IGZ6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000256|ARBA:ARBA00004611}. Dynein axonemal particle {ECO:0000256|ARBA:ARBA00024190}.
Interaction partners:
Sequence:
CPQNNKITKYSLKIWTKSRGVHNKIQVMSASVRNTVTSQENGSIFKRSSNLDNELKKKSVVVNQTQAEESKAKKKDTTHYYSVETLADLQYRSQIKVLEKIYGEEVDMTPKSIQDDTYVEQFMKYNLNVMHQMTNFTTMVAKSTTRSRTRSSVRAGIGGNKQSIDDLMNGILYETINWEPYSTVEALEEAYEPKPYTKSFLKITLRKSDFFEIHSQTQTTVAKGSPEGDDAERDNRNYEYLTIGKGKIRRRSDNDAQTDTLLFTTRAVNTILITKATVSSYVSNFEMYDTLNNITKEFATATMSSVKDLTSALAQTEDADTFEDDEAVAEKDKVSSQIERLFRSPEFRNAIMYMGRTLSSNTNEAGLRRFRNFDQVERWNAEAEYVYSMNLLFRLVPEPSKDERKAVSDIDFCRSNGDILAVAYGLYSFSSQHVPTSGSVFLWSIKNPGEPERAYYYDVPVTAINFSPFLPSLLAIGLYDGSVEVRDVSSLQDTPVAVSQRSTSPGSSPVVAIRWIKQVSDDDHETDIDPFLSLSQDGSVTRFRIIKSPFLLGFTQMILERVEGHPEGIFVHPSSRIPCESNRHPQGLSITTHPLHKDIYYVLTDEGCIHKCSINYQHQYLEVLRCHDGGVTVMEFSPWSPKLFLTCGNDWFVRIWVDGITRPLLELLDEMTPVHWAKWSPTHSTIIVTVNRETANVWDFRRNLLRPMSKHKMDSSFNTVARFSHCGRTLVIGNERGNTLFNALNDMPFSPHFQYDELEKAIFKAIGNDHELLMELKSIGFFGYPNKKAVF
Protein: Rho GDP-dissociation inhibitor (Rho GDI) (Q12434)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Subcellular location: Cytoplasm.
Interaction partners:
- Cell division control protein 42
- GTP-binding protein RHO1
- GTP-binding protein RHO5
- GTP-binding protein RHO4
- Rab GDP-dissociation inhibitor
- GTP-binding protein RHO2
- GTP-binding protein RHO3
- Rho-type GTPase-activating protein 1
- Bud emergence protein 1
- Actin
Sequence:
MAEESTDFSQFEEERNNDQYKVSAKKTVDEYKNLDAEDESLAKWKESLGLSSDVLPLEFPGDKRKVVVQKIQLLVNTEPNPITFDLTNEKTIKELASKRYKIKENSIYKLKIVFKVQHEIITGLRYVQYIKKAGIAVDKIDDHLGSYAPNTKTKPFYEVELPESEAPSGFLARGNYSAVSKFIDDDKTNHLTLNWGVEIVKK
Protein: Integrin beta (D3DSM0)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU000633}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU000633}.
Interaction partners:
Sequence:
MLGLRPPLLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPDSIRCDTRPQLLMRGCAADDIMDPTSLAETQEDHNGGQKQLSPQKVTLYLRPGFGSFVDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVHLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQEQSFVIRALGFTDIVTVQVLPQCECRCRDQSRDRSLCHGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLCHTSDVPGKLIYGQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERTTEGCLNPRRVECSGRGRCRCNVCECHSGYQLPLCQECPGCPSPCGKYISCAECLKFEKGPFGKNCSAACPGLQLSNNPVKGRTCKERDSEGCWVAYTLEQQDGMDRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
Protein: AP-2 complex subunit mu (AP-2 mu chain) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (A0A087WY71)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane, coated pit {ECO:0000256|ARBA:ARBA00004277}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004277}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004277}.
Interaction partners:
Sequence:
MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC
Protein: Alanine racemase, catabolic (EC 5.1.1.1) (P29012)
Organism: Escherichia coli (strain K12)
Function: Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA.
Interaction partners:
- D-amino acid dehydrogenase
- D-alanine--D-alanine ligase A
- D-alanine--D-alanine ligase B
- UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
- Alanine racemase, biosynthetic
- Glutamate-pyruvate aminotransferase AlaA
Sequence:
MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV
Protein: Ceramide synthase 3 (CerS3) (mCerS3) (Dihydroceramide synthase 3) (LAG1 longevity assurance homolog 3) (Sphingosine N-acyltransferase CERS3) (EC 2.3.1.24) (Ultra-long-chain ceramide synthase CERS3) (EC 2.3.1.298) (Very-long-chain ceramide synthase CERS3) (EC 2.3.1.297) (Q1A3B0)
Organism: Mus musculus (Mouse)
Function: Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very- and ultra-long-chain fatty acyl-CoA (chain length greater than C22). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. It is crucial for the synthesis of ultra-long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:22038835}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Phosphatidylcholine:ceramide cholinephosphotransferase 1
- Ceramide glucosyltransferase
- Alkaline ceramidase 1
- 3-ketodihydrosphingosine reductase
- Acid ceramidase
- Alkaline ceramidase 3
- Sphingomyelin phosphodiesterase
- Sphingolipid delta
- Alkaline ceramidase 2
- Neutral ceramidase
Sequence:
MFQTFRKWFWSERYWLPPTIKWSDLEDHDGLVFVKASHLYITIPYAFLLMVVRYFFEKFVATPLANALGIKKTQHKIKPNAILENFFKHSTSKPSHTDIYGLAKKCNLTERQVERWLRIRQKQNKPCRLQKFQESCWRFTFYLLITMAGAVFLYDKPWAYDLWEVWNDYPRQPLLPSQYWYYILEMSFYWSLVFSLSTDIKRKDFLAHVIHHLAAISLMSFSWCANYIRSGTLVMFIHDISDIWLESAKMFSYAGWKQTCNTLFFIFTVVFFISRFIIFPFWILYCTLILPLHYLEPFFSYIFLNLQLMILQGLHVYWGYFILKMLNRCIFTQNVQDVRSDNEEEEEEEEEEEAESTKGKETEYLKNGLGTNRHLIANGQHGR
Protein: Sodium/hydrogen exchanger (M9PDW6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSIRTEQDYDSATPALAQQMNLARRACWRIKSYSSESLFKTYASVITDTSANEIDAEAPPPPRDKTKTRIEPQIAPAKRNSSCTSSDWRGMFSKRTLLICALALILGSAQARPNTSAVGVAPRKVSQDIVDAVTQLNLGQSAPIDAVDVGLDPTPSARVPRPEPLKSGDENAKGDEGHKMERYPLSSVDFARVKTPFIIGIWILSASIAKIGFHMTPKLHLIFPESCLLIVVGVVIGVVLYFCTDVAVSPLTPNTFFFYMLPPIILDAGYFMPNRLFFDNLGTILLMAVVGTIFNIATIGGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAVFEEIHVNEILYIVVFGESLLNDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVVALGGTAIGIIWGFLTGLVTRFTDHVRVIEPIFIFVMAYLAYLNAEIFHMSGILAITFCGITMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATVNNMHVWNTWFVVLTIAFCSVFRVIGVILLSALANRFRLHKLSRVDQFVMSYGGLRGAVAFALVLLVDENVVKQKNMFVTTTIAVIYFTVFLQGITIKPLVKILNVKRANKRKPTMNERIHERFMDHLMAGIEDIVGKTGNYNVRDKFKRFDNRFIRPLLIRDLKGAEPKIIETYSKLTMRDAMEVMRRNPSTIGQMTGTESMSALFRNYTNNYIGGRWAPPTIYTTCPSLTNLDNTCSRNLDMAELDYNPSKKDLTDARIHHLLAEELKPYRRASIQMHRRLSYSRHAVDDRDLSTQVNYKMQMNFRRMFNDRKHHKRSKRGASNKAKENVKQNHVSFHDFQQNGTTKQLTNAEECQQNPNEINVVGPSDDWDDGLTFTAKSSPDSDRANNNSLIAHIQNLPGFDASKARIVVQHYAPKADDNPDTDIESPEQAIGPTAAELILPWRRDRSYQSIVAEHPIPEEDRNLSRESDGERRVATPTATESQLPWKRQGDECTDAVQQNEFPAWASNKEYLAYNSPSATFLGGINKPKQPKSVIGLFRRESSSSKAGSVGVGSTGAMDSAASGSETMVVSMSSQPPNAPSTSIHNPRLDKRSQSISSSSLGAGAHQLGPEGHSGPFPVTASHRRNVRRGSMLELSGDTIPEESSYQHGHSKSLCEPADSDEWEGAPLSAAGGANSELLMRMSGREPLLPRPSNTPRAQIRRMNAGAVGGAGVSQAGRKNQVTKALLDYEDSETDSDENDDDEDEDFDSYDDENIVVTTFTTPATGRRPGSSPGSGSEANTATTTTTSIRLTRNNDESII
Protein: Potassium channel SKOR (Stelar K(+) outward rectifying channel) (Q9M8S6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Highly selective outward-rectifying potassium channel. Involved in potassium release into the xylem sap toward the shoots. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. The voltage-dependence of the channel is abolished by internal or external acidification. May interact with the cytoskeleton or with regulatory proteins.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Potassium transporter 5
- Sodium transporter HKT1
- Potassium transporter 7
- Two-pore potassium channel 4
- Sodium/hydrogen exchanger 1
- Potassium inward rectifier
- Sodium/hydrogen exchanger 7
- Protein NRT1/ PTR FAMILY 7.3
- Sodium/hydrogen exchanger 2
- Potassium transporter 6
Sequence:
MGGSSGGGVSYRSGGESDVELEDYEVDDFRDGIVESRGNRFNPLTNFLGLDFAGGSGGKFTVINGIRDISRGSIVHPDNRWYKAWTMFILIWALYSSFFTPLEFGFFRGLPENLFILDIAGQIAFLVDIVLTFFVAYRDSRTYRMIYKRSSIALRYLKSTFIIDLLACMPWDIIYKAAGEKEEVRYLLLIRLYRVHRVILFFHKMEKDIRINYLFTRIVKLIFVELYCTHTAACIFYYLATTLPASQEGYTWIGSLKLGDYSYSKFREIDLWTRYTTSMYFAVVTMATVGYGDIHAVNMREMIFAMVYISFDMILGAYLIGNMTALIVKGSKTERFRDKMADIMRYMNRNKLGRNIRGQITGHLRLQYESSYTEAAVLQDIPVSIRAKIAQTLYLPYIEKVPLFRGCSSEFINQIVIRLHEEFFLPGEVIMEQGSVVDQLYFVCHGVLEEIGITKDGSEEIVAVLQPDHSFGEISILCNIPQPYTVRVAELCRILRLDKQSFMNILEIFFHDGRRILNNLLEGKESNVRIKQLESDITFHISKQEAELALKLNSAAFYGDLYQLKSLIRAGGDPNKTDYDGRSPLHLAASRGYEDITLYLIQESVDVNIKDKLGSTPLLEAIKNGNDRVAALLVKEGATLNIENAGTFLCTVVAKGDSDFLKRLLSNGIDPNSKDYDHRTPLHVAASEGFYVLAIQLVEASANVLAKDRWGNTPLDEALGCGNKMLIKLLEDAKNSQISSFPSGSKEPKDKVYKKKCTVYFSHPGDSKEKRRRGIVLWVPRSIEELIRTAKEQLNVPEASCVLSEDEAKIIDVDLISDGQKLYLAVET
Protein: Dishevelled binding antagonist of beta catenin 1 (cDNA FLJ51077, highly similar to Dapper homolog 1) (cDNA, FLJ79063, highly similar to Dapper homolog 1) (cDNA, FLJ79136, highly similar to Dapper homolog 1) (B7Z673)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV
Protein: Wtf element wtf7 (A0A482APM8)
Organism: Schizosaccharomyces kambucha (Fission yeast)
Function: May act in meiotic drive.
Subcellular location: Spore membrane {ECO:0000255, ECO:0000269|PubMed:32032353}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLKMSGSYAPVEDSADELSVHSGNDNEIDLEKGLLPKCNTGNGGTTPCSEPPHYDSDAVVEMDMYENNIYMQTFKLRPFPKSGVTNFSNVVFQMKTYENNRHMQTFRLRPFAKNGVTNGVKLAQVLFLLLPFNFIFIACLFFRKASFTDFSLMGWILFGIWCLTCFLSSFILYAYHESWTKFARERPDDFAGILILLLFPGIVTMIVFYGIYMNSIYG
Protein: Arginine methyltransferase 8 (RE49877p) (Q8SX32)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Alpha N-terminal protein methyltransferase 1
- Ribosome assembly factor mrt4
- Protein arginine N-methyltransferase 5
- H/ACA ribonucleoprotein complex subunit 2
Sequence:
MANTYFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLVYAVEASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLLARDKFLKEGGLLFPSECTIFVAPCSVPSLFDDWHNVDGIKMDTFARKLRTQKSSRPEITQLNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAGNHQGFCIWFDVQFPGEDFVLSTSPLSPPTHWKQCVVVLPEESCENLEEKSPIAFQITMKRSAADMRKYNLEVDLLDPNTEEHPVPCSCHMTKCILTEAHLKMMDTS
Protein: Oxytocin-neurophysin 1 (OT-NPI) [Cleaved into: Oxytocin (Ocytocin); Neurophysin 1] (P01179)
Organism: Rattus norvegicus (Rat)
Function: Neurophysin 1 specifically binds oxytocin.
Interaction partners:
- Oxytocin receptor
- Vasopressin V1a receptor
- Corticoliberin
- Pro-opiomelanocortin
- Prolactin
- Galanin peptides
- Pro-neuropeptide Y
- Prolactin-6A1
- 5-hydroxytryptamine receptor 1A
- Pro-thyrotropin-releasing hormone
Sequence:
MACPSLACCLLGLLALTSACYIQNCPLGGKRAALDLDMRKCLPCGPGGKGRCFGPSICCADELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCATAGICCSPDGCRTDPACDPESAFSER