wanglab/gogpt-training-data huggingface dataset:
Protein: Protein BFR2 (Brefeldin A resistance protein 2) (Q06631)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in endoplasmic reticulum to Golgi transport. Involved in a protein-transport step blocked by brefeldin A, which disrupts the Golgi apparatus and its incoming protein flux. May also be involved for mass growth or cell proliferation.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- U3 small nucleolar RNA-associated protein MPP10
- RNA cytidine acetyltransferase
- Small ribosomal subunit protein eS7A
- Small ribosomal subunit protein uS17A
- Regulator of rDNA transcription protein 14
- rRNA processing protein RCL1
- Small ribosomal subunit protein uS4A
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 13
- Ribosome biogenesis protein ENP2
Sequence:
MEKSLADQISDIAIKPVNKDFDIEDEENASLFQHNEKNGESDLSDYGNSNTEETKKAHYLEVEKSKLRAEKGLELNDPKYTGVKGSRQALYEEVSENEDEEEEEEEEEEKEEDALSFRTDSEDEEVEIDEEESDADGGETEEAQQKRHALSKLIQQETKQAINKLSQSVQRDASKGYSILQQTKLFDNIIDLRIKLQKAVIAANKLPLTTESWEEAKMDDSEETKRLLKENEKLFNNLFNRLINFRIKFQLGDHITQNEEVAKHKLSKKRSLKELYQETNSLDSELKEYRTAVLNKWSTKVSSASGNAALSSNKFKAINLPADVQVENQLSDMSRLMKRTKLNRRNITPLYFQKDCANGRLPELISPVVKDSVDDNENSDDGLDIPKNYDPRRKDNNAIDITENPYVFDDEDFYRVLLNDLIDKKISNAHNSESAAITITSTNARSNNKLKKNIDTKASKGRKLNYSVQDPIANYEAPITSGYKWSDDQIDEFFAGLLGQRVNFNENEDEEQHARIENDEELEAVKNDDIQIFG
Protein: ATPase family AAA domain containing 3A (Q5SV16)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLYRTGQHSNNPSHVSHGGSSPAGRPWLTPQARWAPRFMLVLASNQPEQFDWAINDRINEMVHFDLPGQEERERLVRMYFDKYVLKPATEGKQRLKLAQFDYGRKCSEVARLTEGMSGREIAQLAVSWQATAYASEDGVLTEAMMDTRVQDAVQQHQQKMCWLKAEGPGRGDEPSPS
Protein: BTB/POZ domain and ankyrin repeat-containing protein NOOT1 (Protein NODULE ROOT 1) (MtNOOT1) (Q2HW56)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: Involved in the promotion of leaf and floral meristem fate and determinacy. Promotes normal stipule growth and development. Involved in the coordination of the symbiotic nodule developmental program. Necessary for the robust maintenance of nodule identity throughout the nodule developmental program. Involved in the regulation of indeterminate nodule identity in association with NOOT2.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:G3LSH3}. Cytoplasm {ECO:0000250|UniProtKB:G3LSH3}. Cell membrane {ECO:0000250|UniProtKB:G3LSH3}; Peripheral membrane protein {ECO:0000250|UniProtKB:G3LSH3}; Cytoplasmic side {ECO:0000250|UniProtKB:G3LSH3}.
Interaction partners:
- Leucine zipper transcription factor
- BZIP family transcription factor
Sequence:
MSLEDSLRSLSLDYLNLLINGQAFSDVVFSVEGRLVHAHRCILAARSLFFRKFFCGPDPPSGLDPSGNRVNPSGSARSGVIPVNSVGYEVFLLMLQFLYSGQVSIVPQKHEPRPNCGDRGCWHTHCTSAVDLALDTLAAARYFGVEQLALLTQKQLASMVEKASIEDVMKVLLASRKQDMHQLWTTCSHLVAKSGLPPEVLAKHLPIDIIAKIEELRIKTSLSRRSLMPHHHHPHHHDHLTAAADLEDQKIRRMRRALDSSDVELVKLMVMGEGLNLDEALALPYAVENCSREVVKALLELGAADVNFPAGPTGKTPLHIAAEMVSPDMVAVLLDHHADPNVRTVDGVTPLDILRTLTSDFLFKGAVPGLTHIEPNKLRLCLELVQSAALVMSREEGNNNNSNNNNNATASSATNMYPHHNMNEDHHHSHNNNNMDSRLVYLNLGANTQMSTSRMDSGDDDNTHREAINNSMYHHHSHGHDY
Protein: Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1) (P62495)
Organism: Homo sapiens (Human)
Function: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24486019}.
Interaction partners:
- Serine/threonine-protein kinase SMG1
- ATP-binding cassette sub-family E member 1
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3B
- Regulator of nonsense transcripts 1
- Large ribosomal subunit protein uL11
- Nonsense-mediated mRNA decay factor SMG8
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS10
Sequence:
MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY
Protein: Thymidine kinase (EC 2.7.1.21) (Q9WYN2)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Thymidylate kinase
- Cytidine/deoxycytidine deaminase
- Deoxycytidylate deaminase, putative
- Flavin-dependent thymidylate synthase
- Pyrimidine-nucleoside phosphorylase
- UDP-sugar hydrolase
- 5'-nucleotidase SurE
- Purine nucleoside phosphorylase
- Purine nucleoside phosphorylase
- Peptide chain release factor 1
Sequence:
MSGKLTVITGPMYSGKTTELLSFVEIYKLGKKKVAVFKPKIDSRYHSTMIVSHSGNGVEAHVIERPEEMRKYIEEDTRGVFIDEVQFFNPSLFEVVKDLLDRGIDVFCAGLDLTHKQNPFETTALLLSLADTVIKKKAVCHRCGEYNATLTLKVAGGEEEIDVGGQEKYIAVCRDCYNTLKKRV
Protein: ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein) (Q8NE71)
Organism: Homo sapiens (Human)
Function: Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Subcellular location: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:19570978}. Nucleus, nucleoplasm {ECO:0000269|PubMed:19570978}. Nucleus envelope {ECO:0000269|PubMed:19570978}.
Interaction partners:
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein uS12
- Large ribosomal subunit protein uL1
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS28
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein eL38
- Small ribosomal subunit protein eS21
Sequence:
MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMVSRPRE
Protein: Berberine bridge enzyme-like 2 (AtBBE-like 2) (EC 1.1.1.-) (Q9SA99)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted, cell wall {ECO:0000250|UniProtKB:O64743}.
Interaction partners:
Sequence:
MKIFCLILFLISSFISTSLAVEPPPETIYQNFLQCFTNQTKAPPNSLADVVLPKTAAAFTPVLRAYIRNARFNTTATPKPAIVIAARSESHVQAAVICTKSLNIQLKTRSGGHDYEGVSYISHVPFFVLDMSNLRNITVDPATESAWVGAGATLGEVYYRIWEKTKSHGFPAGVCPTVGAGGHISGGGYGNMIRKYGLSVDYVTDAKIVDVNGQVLDRKGMGEDMFWAINGGGGASFGVILAFKIKLVPVPPTVTVFRVEKNLVENATEMVHKWQFVAPKTDPGLFMRLLLQPVTRNKMQTVRASVVALFLGDQNTVMSMLTKEFPELGLKKENCTEMTWIQSVMWWANNDNATQIKPEILLDRNPDMATFGKRKSDFVEKEITKDGLDFLFKKMIEVGKIGLVFNPYGGIMSTVATTKTPFPHRKKLYKIQHSMNWKDPGTEAETSFLQKAKSFYSYMAPFVTKNPRHTYINYRDLDIGVNTPGPNSYRVAEVFGRMYFGENFDRLVKVKTAVDPQNFFRDEQSIPTLPGKPARR
Protein: Protein DOWN-REGULATED IN DIF1 11 (Q9C924)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Defensin-like protein 44
- At4g07515)
- Inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Defensin-like protein 181
- Egg cell-secreted protein 1.3
- Mannan endo-1,4-beta-mannosidase 3
- Annexin D8
- Protein RKD2
- Protein LURE 1.2
- Egg cell-secreted-like protein
Sequence:
MEKAILITFLIATTSMVYQTIGQEEEISPISPESLAYEPAAAYEYDHELLSHMTTRRIKFLQDCSDKMSSKCNVEMTEGLIDDKPVSEDCCVNFLKIGRECHEGLMTFVFATYELKDVASAILPRSKRMWNKCVETTAAKIGAPLAFET
Protein: Uncharacterized protein (Q388J6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLSLTFLLLAFLLMATESQSFEVLPLNVTHLSTGNGLWMPSGAVTLQEGVICAQAYQEPCAECKHQLTAVCTFDGGKSFSVQQTKYPFCAHRGVVVGGTLHCPLKVDNVSQNVINITVVSYKGNVSLLENEENTTMTFSYIPGEEVTDIEFRGNTLFLTDDQIYLMNAVVKRNTSLVHVLFQSDDGYIWSVRSKIPLDPLDNAELMLRGRNRLMVSTYNSSHHYVVSSGYQGRWWGSVHYVDTESRPAALAVGNGISIESGITNKSGLLELAGLVEGKPKVKSVSLVDLYKNVTNASQIPDNFTLGCDNELPCLTTSHIALMRTREGNMTALFGFVSTTTKRKTVVGLTLLIDDTEEKNERLAELRKLEEEAKQREEARLKYLRDLEEKKQKEREEKLRREQERLLKFQNTDEENIKIAVSRLSEDGEMIVVREVDPDLVDLEKQAFFW
Protein: SPS-sensor component PTR3 (Peptide transport protein 3) (P43606)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10409731, ECO:0000269|PubMed:11154269}; Peripheral membrane protein {ECO:0000269|PubMed:10409731, ECO:0000269|PubMed:11154269}; Cytoplasmic side {ECO:0000269|PubMed:10409731, ECO:0000269|PubMed:11154269}.
Interaction partners:
- SPS-sensor component SSY1
- SPS-sensor serine protease component SSY5
- Transcription factor STP2
- Leu/Val/Ile amino-acid permease
- Transcription factor STP1
- General amino-acid permease GAP1
- ERAD-associated E3 ubiquitin-protein ligase ASI1
- Protein ASI2
- Peptide transporter PTR2
- General amino acid permease AGP1
Sequence:
MHSHRQKWGRQTDIARVLDDIEHDLYLPQRLSLDGATGTDESHVQYGIVKDCSVLTCGCCISESLFNDLCRETSNKQTACPICQRENVRLLSAIKPLRDLARQIDFFRSTTGQGESESDELPAIVKTSPSSSSLSLTPSRSSSTAGLEADNKTLSDPTVKEKSSLLELFHIVASKMHNANTEVGSDHPLTTGTTRDQEEHTTKENYSSSLLEPNYDDHANWKILDNASNTRTVPIDNNFSLMSTDVTIPSTANYQTNSAHDLDEEKEYFFANCFPMYRKKFQFNTHPKFLGTKSKLFINQSISPDCTKFALITEHKWEIYSINPKDNSPQLVSCGKSSGEYGPNFNQLTEQSSSSLSTTSQASKKKKKNWSQRFCKLSNDFLIISGSQNILNVHDIHQNGKLIYTYVSRFPIRCIDIDPRSQIIAYGITGKDRHTGAEQALVVIQQITRNKVTLEPEFPPPITITLPYRDPINTIQLSHDAKYLTCSTALESRFLIISLQKINEPRLIMKSVRSIDTSLESEGITDTKLFPGNPNLMCITSTAFNSSPLVINTKITQINGVRTVAQPSMLIRVDEIGCKIHKCEISPRNDAIAFLDRNGSVYIMCAPTMMDNNEKRRTILVETVANAYRAYESATLRFNPEGNKLYILDRKGTFFVEDFAYGLPQSREITKCKQIFHK
Protein: Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2) (O08537)
Organism: Mus musculus (Mouse)
Function: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q92731}.
Interaction partners:
- Nuclear receptor coactivator 1
- Transcription factor Sp1
- Nuclear receptor coactivator 2
- Nuclear receptor coactivator 3
- Nuclear receptor coactivator 5
- Estrogen receptor
- Proto-oncogene tyrosine-protein kinase Src
- Protein c-Fos
- Transcription factor Jun
- Mediator of RNA polymerase II transcription subunit 1
Sequence:
MEIKNSPSSLTSPASYNCSQSILPLEHGPIYIPSSYVESRHEYSAMTFYSPAVMNYSVPSSTGNLEGGPVRQTASPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVNRETLKRKLGGSGCASPVTSPSAKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSASEQVHCLNKAKRTSGHTPRVKELLLNSLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTARFRELKLQHKEYLCVKAMILLNSSMYPLATASQEAESSRKLTHLLNAVTDALVWVISKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGYKSSISGSECCSTEDSKSKEGSQNLQSQ
Protein: RE23893p (Q867T3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAALQRKLVHKQFNSPMGLYSQENVKATLNRELKAFGGEGIEVDDQITKPLNLANSAVLRAVEEEEQQAKCGYKRVAWPPASEERIIREFTPQPQTQSPAPGAGGYYPQAHAPTAAAAAPPQQQQYGAPSYDGQQPGAQWQQQQQQQQVPQQQYQPQSQAQAPYQPPQWNQPQQQQQQPSYQASPYQQQQQQQPSYYPQQNGGSTYAQPPYNSYSQPQLPYSQDQTDLQQQQQQQQQQYPGAYAGQDSYRGASPGIITLRKEAPVSQKPAPVYTSQPAAVSYQGGSKLRGDLKWPPPEYKEAAARENEERRQLALGPVCRPRRVNRDYTPFFAKHQLNNGYPSYKVPPGTQHIFG
Protein: Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase (AtAAT) (AtPPA-AT) (EC 2.6.1.1) (EC 2.6.1.78) (EC 2.6.1.79) (Protein MATERNAL EFFECT EMBRYO ARREST 17) (Q9SIE1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Prokaryotic-type aspartate aminotransferase. Has also a prenate transaminase activity. Involved in the aromatic amino acids biosynthesis pathway via the arogenate route. Required for the transamination of prephenate into arogenate. Required for early development of the embryo.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:16623902}.
Interaction partners:
- Arogenate dehydrogenase 2, chloroplastic
- Arogenate dehydratase/prephenate dehydratase 6, chloroplastic
- Arogenate dehydratase 3, chloroplastic
- Arogenate dehydratase 4, chloroplastic
- Arogenate dehydratase 5, chloroplastic
- Chorismate mutase 1, chloroplastic
- Arogenate dehydratase/prephenate dehydratase 2, chloroplastic
- Chorismate mutase 3, chloroplastic
- Chorismate mutase 2
- Arogenate dehydratase/prephenate dehydratase 1, chloroplastic
Sequence:
MASQSSVAVISSAAARGESFPDSKKPIGSVRFQQPLRLSFSYCKSGNMSSRICAMAKPNDAETLSSSVDMSLSPRVQSLKPSKTMVITDLAATLVQSGVPVIRLAAGEPDFDTPKVVAEAGINAIREGFTRYTLNAGITELREAICRKLKEENGLSYAPDQILVSNGAKQSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVIPTKISNNFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLLVLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYLAGPKHIVAACSKLQGQVSSGASSIAQKAGVAALGLGKAGGETVAEMVKAYRERRDFLVKSLGDIKGVKISEPQGAFYLFIDFSAYYGSEAEGFGLINDSSSLALYFLDKFQVAMVPGDAFGDDSCIRISYATSLDVLQAAVEKIRKALEPLRATVSV
Protein: L-lactate dehydrogenase (Q76NM3)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase
- Pyruvate kinase
- Citrate synthase-like protein, putative
- Citrate synthase
- Succinate--CoA ligase subunit beta, mitochondrial
- Isocitrate dehydrogenase
- Fumarate hydratase
- Hypoxanthine phosphoribosyltransferase
- pyruvate kinase
- Aspartate aminotransferase
Sequence:
MAPKAKIVLVGSGMIGGVMATLIVQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPVDVMVQLLHQHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNAHIVGAHGNKMVLLKRYITVGGIPLQEFINNKLISDAELEAIFDRTVNTALEIVNLHASPYVAPAAAIIEMAESYLKDLKKVLICSTLLEGQYGHSDIFGGTPVVLGANGVEQVIELQLNSEEKAKFDEAIAETKRMKALA
Protein: Toxin-antitoxin biofilm protein TabA (P0AF96)
Organism: Escherichia coli (strain K12)
Function: Influences biofilm formation. Represses fimbria genes in 8 hours biofilms. May act in response to the combined activity of several toxin-antitoxin (TA) systems.
Interaction partners:
- Uncharacterized fimbrial-like protein YcbV
- Uncharacterized protein YjgL
Sequence:
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGAPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (F4I9N7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MESHLGNGVGSSRSAKNTKNTSSSVDWLSRDMLEMKIRDKTEADEERDSEPDIIDGVGAEPGHVITTTLPGRNGQSRQTVSYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQMLDHPNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELRDPNARLPNGRPLPPLFNFKPQELSGIPPETVDRLVPEHARKQNHFMALHSCLRIPCREVRMRKIQHYFVRYMI
Protein: ATP synthase F(0) complex subunit C2, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase membrane subunit c locus 2) (ATP synthase proteolipid P2) (ATPase protein 9) (ATPase subunit c) (Q06646)
Organism: Rattus norvegicus (Rat)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
Subcellular location: Mitochondrion membrane; Multi-pass membrane protein.
Interaction partners:
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit d, mitochondrial
- ATP synthase F
- ATP synthase peripheral stalk subunit F6, mitochondrial
- ATP synthase peripheral stalk subunit b, mitochondrial
Sequence:
MYACSKFVSTRSLIRSTSQLLSRPLSAVELKRPQMPTDEGLSCLAVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
Protein: PDZ and LIM domain protein Zasp (G5EFL5)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Alpha-actinin, sarcomeric
- Muscle M-line assembly protein unc-89
- PDZ domain-containing protein
- Vinculin
- CRE-UNC-96 protein
- protein kinase C
- Zinc finger protein unc-98
- Sorbin and SH3 domain-containing protein 1 homolog
- LIM domain-containing protein unc-95
- Protein unc-112
Sequence:
MERVTVRMARSDRRTPWGFGVTEAPDGAVLIVNVIGGSLADRAGLRNGDVVDRLEDLDNLDINAVDRLLVTAHEKIELIVTRQPSGAATRIWRPEVTENTGPGQDQTPYRVNLQHSSDTRPPQGFNNSALPFETDQRVKHMQYNSPLGIYSDKSAAEQYVQQTQGLGDNSGARAAAQRQDEPAYLRSETLRLLKEQEHGSAGGAGTTLSNHPNPSGLPVCFMCTRPILGVMARAAGKNLHGDCLSCATCGNSLRNVGHHFIEDKFYCDIHGTQRKHGGRPGMDPNIFVKSSPTAAQPVHIQDSPRAAYHPQVNTARPVSVSPAPSAGSKTVTTHYHTPKTQGILSPGQRGVPTAAFGADLSKSVTYGGGVGPGGTHYDSNRLSPAPSQYSTQSRNQSQQHYQQHVVQAPPPVPSNPPPSNEQQSQSRVQNLPDSVRSAVSPRRSGKSPRQWPPPAMPTTNRYWQIDPADALKKEKVNYGEDLVALIKEVEQSKEKEPKVKKEPKKGTRGARRASNISKEQVQQAFEEQRKRTERKEIKKLEKEIKPKPELKVEVPVEPLVVPTSKPLEEPCPEALPPPKINDGIHWTVIHSPVLRSPSPAKVTSEAAIPESNGVVKPIPSYASQPIGISKTSTPQPFRPGSQVERPHYSSVGLKDVHAPVPLPRSPQHSPQPVQSYIVRSSDANVTTSTNLQTTVTRQYTENDNKSQFLQQPHPDTIDSSTSPIPTIRLNRHTKPEPSTPLSVPTVSINDIATSPIKITEPSRPWRASVSNSATSPIKIHESRVQPVDESRGLHRHEEKAQIETSTIKIHEPSSPPPSVHKFGAVNTRAAPAPVQFMQTPRIAVKIHEPTGPSPTPPSTPSHPIKRDPKHFKKVDFSKTSPTVIPEWKDSADIVDESDILTECSREDDSISFLKAATYDGDESEMIDNNIDNKSDITSTFDIEEEEVDVVQDRERIRVVGRKGGEGGEAEKQWRQRAMELLDDDAQTERDLRIVAALNERLQGLREMEDDDRVRAIECIARHQSELEQTQTQLSTLLESAIVYLQNLRPELELTEPIDNDAKSLETVKFEPTRAEQRVNEIRKKVLEDLEHLPILGDGMDSVPPPPPERKVFPFQSYQPIAPQFPVPAAESPVTQSLHDVLDEFYSLRKPTPTQNVAQSSDTTAEDSRNFLASRLGQVMIDENKKAGGSNGSSQHHNQQGSSYTKTSFERTTTETRPQQNTGAPRAGDFRGTGHLTTTTTTQQNGGRAPFCESCKQQIRGAFVLATGKSWCPEHFVCANSSCRRRLLECGFVEEDGQKFCESCFEQHIAPRCNKCSKPIISDCLNALQKKWHPTCFTCAHCQKPFGNSAFYLEQGLPYCEQDWNALFTTKCVSCRYPIEAGDRWVEALGNAFHSNCFTCARCNHNLEGESFFAKNGQPFCRLHA
Protein: Protein SHQ1 homolog (Q6PI26)
Organism: Homo sapiens (Human)
Function: Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:19383767}. Nucleus, nucleoplasm {ECO:0000269|PubMed:19383767}. Note=May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit DKC1
- H/ACA ribonucleoprotein complex subunit 1
- H/ACA ribonucleoprotein complex subunit 3
- H/ACA ribonucleoprotein complex subunit 2
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- RuvB-like 1
- RuvB-like 2
- Telomerase Cajal body protein 1
- Pseudouridylate synthase TRUB1
- Pseudouridylate synthase TRUB2, mitochondrial
Sequence:
MLTPAFDLSQDPDFLTIAIRVPYARVSEFDVYFEGSDFKFYAKPYFLRLTLPGRIVENGSEQGSYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRKSRTAKPLVEEIGASEIPEEVVDDEEFDWEIEQTPCEEVSESALNPQCHYGFGNLRSGVLQRLQDELSDVIDIKDPDFTPAAERRQKRLAAELAKFDPDHYLADFFEDEAIEQILKYNPWWTDKYSKMMAFLEKSQEQENHATLVSFSEEEKYQLRKFVNKSYLLDKRACRQVCYSLIDILLAYCYETRVTEGEKNVESAWNIRKLSPTLCWFETWTNVHDIMVSFGRRVLCYPLYRHFKLVMKAYRDTIKILQLGKSAVLKCLLDIHKIFQENDPAYILNDLYISDYCVWIQKVKSKKLAALAEALKEVSLTKAQLGLELEELEAAALLVQEEETALKAAHSVSGQQTLCSSSEASDSEDSDSSVSSGNEDSGSDSEQDELKDSPSETVSSLQGPFLEESSAFLIVDGGVRRNTAIQESDASQGKPLASSWPLGVSGPLIEELGEQLKTTVQVSEPKGTTAVNRSNIQERDGCQTPNN
Protein: POTE ankyrin domain family member E (ANKRD26-like family C member 1A) (Prostate, ovary, testis-expressed protein on chromosome 2) (POTE-2) (Q6S8J3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSKMGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVPSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
Protein: Damage-regulated import facilitator 1 (O13577)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mediates the nuclear localization of RNR2 and RNR4, 2 subunits of the ribonucleotide reductase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18838542}. Nucleus {ECO:0000269|PubMed:18838542}.
Interaction partners:
- Ribonucleotide reductase inhibitor protein SML1
- DNA damage response protein kinase DUN1
- Transcriptional modulator WTM1
- Ribonucleoside-diphosphate reductase small chain 2
- Ribonucleoside-diphosphate reductase small chain 1
- Ribonucleoside-diphosphate reductase large chain 1
- Serine/threonine-protein kinase MEC1
- Ribonucleoside-diphosphate reductase large chain 2
- MEC1-mediated checkpoint protein HUG1
- Serine/threonine-protein kinase RAD53
Sequence:
MDAQLEWASSLVPKRQLQQQQQQQEQQQQQQQDFHKDQLMTVGMRIRQRVDQGYASRTPSTSDASLQPGVIRDYSSVIVPQFTRSPLPTANSLPPMLINQRTMSTEASSLEKWDVAEPAAEHETMVNGSKRRL
Protein: DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (Gal_Lectin domain-containing protein precursor) (E9QFV1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Netrin receptor UNC5
- Si:ch73-72b7.1.
- Netrin receptor UNC5
- Unc-5 netrin receptor C.
- Netrin receptor UNC5
- Vascular endothelial growth factor A-A
- Vascular endothelial growth factor Bb
- Si:ch211-166i24.1.
- Teneurin-4
- SUZ RNA-binding domain-containing
Sequence:
MGSLGVVSALVLLSCGLLISVSAIPAIQGSELDYTETTCLDSDLSLSCDDGVIFVKSARFGWRSTRLCGPGRPHFETDPARCLREIPIIPKWCNGQATCMINKEKIGRPHRCFFTHYTTTYICIPAKTIEICEDERGLLRCGNGRIKVIAANYGRTDGTTCLRRPPFRRRLNTNCYSQNTLDLVSQRCDGRRRCSLTATNDVFSDPCAGTRKYLKITYYCQS