wanglab/gogpt-training-data huggingface dataset:
Protein: Iroquois-class homeodomain protein IRX-2 (Homeodomain protein IRXA2) (Iroquois homeobox protein 2) (Q9BZI1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL
Protein: Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein) (U11/U12-20K) (Q9UDW3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:15146077}.
Interaction partners:
- RNA-binding region-containing protein 3
- U11/U12 small nuclear ribonucleoprotein 35 kDa protein
- U11/U12 small nuclear ribonucleoprotein 48 kDa protein
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein F
- Small nuclear ribonucleoprotein Sm D3
- Small nuclear ribonucleoprotein Sm D2
- Zinc finger CCHC-type and RNA-binding motif-containing protein 1
- Programmed cell death protein 7
- Splicing factor 3B subunit 1
Sequence:
MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSIQVEEERRAREWLLDAPELPEGHLEDWLEKRAKRLSSAPSSRAEPIRTTVFQYPVGWPPVQELPPSLRAPPPGGWPLQPRVQWG
Protein: Inter-alpha-trypsin inhibitor heavy chain H6 (Inter-alpha-trypsin inhibitor heavy chain H5-like protein) (Inter-alpha inhibitor H5-like protein) (Q6UXX5)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MSGWRYLICVSFLLTILLELTYQGPPVPASSSTKLLMTSYSMRSTVVSRYAHTLVTSVLFNPHAEAHEAIFDLDLPHLAFISNFTMTINNKVYIAEVKEKHQAKKIYEEAHQQGKTAAHVGIRDRESEKFRISTSLAAGTEVTFSLAYEELLQRHQGQYQLVVSLRPGQLVKRLSIEVTVSERTGISYVHIPPLRTGRLRTNAHASEVDSPPSTRIERGETCVRITYCPTLQDQSSISGSGIMADFLVQYDVVMEDIIGDVQIYDDYFIHYFAPRGLPPMEKNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTVNVWKAGGSIQATIQNVHSAKDYLHCMEADGWTDVNSALLAAASVLNHSNQEPGRGPSVGRIPLIIFLTDGEPTAGVTTPSVILSNVRQALGHRVSLFSLAFGDDADFTLLRRLSLENRGIARRIYEDTDAALQLKGLYEEISMPLLADVRLNYLGGLVGASPWAVFPNYFGGSELVVAGQVQPGKQELGIHLAARGPKDQLLVAHHSEGATNNSQKAFGCPGEPAPNVAHFIRRLWAYVTIGELLDAHFQARDTTTRHLLAAKVLNLSLEYNFVTPLTSLVMVQPKQASEETRRQTSTSAGPDTIMPSSSSRHGLGVSTAQPALVPKVISPKSRPVKPKFYLSSTTTASTKKMLSSKELEPLGESPHTLSMPTYPKAKIPAQQDSGTLAQPTLRTKPTILVPSNSGTLLPLKPGSLSHQNPDILPTNSRTQVPPVKPGIPASPKADTVKCVTPLHSKPGAPSHPQLGALTSQAPKGLPQSRPGVSTLQVPKYPLHTRPRVPAPKTRNNMPHLGPGILLSKTPKILLSLKPSAPPHQISTSISLSKPETPNPHMPQTPLPPRPDRPRPPLPESLSTFPNTISSSTGPSSTTTTSVLGEPLPMPFTPTLPPGRFWHQYDLLPGPQRTRQVLGPSRPGVPTMSLLNSSRPTPEGSPPNLPILLPSSILPEAISLLLLPEELELLSESMVESKFVESLNPPAFYTFLTPDEDGSPNWDGNSEEILGGAGGSMESQGSSVGLAKGTLPSIFTFSSSVDGDPHFVIQIPHSEEKICFTLNGHPGDLLQLIEDPKAGLHVSGKLLGAPPRPGHKDQTRTYFQIITVTTDKPRAYTITISRSSISLRGEGTLRLSWDQPALLKRPQLELYVAAAARLTLRLGPYLEFLVLRHRYRHPSTLQLPHLGFYVANGSGLSPSARGLIGQFQHADIRLVTGPMGPCLRRHHGPDVPVILGKRLLKDSPRLLPRWASCWLVKRSHVELLLGHPYLSYVL
Protein: Nuclear receptor coactivator 5 (B5X1C7)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
- E3 SUMO-protein ligase RanBP2
- E3 SUMO-protein ligase RanBP2
- Nuclear pore complex protein Nup93
- Nuclear pore complex protein Nup205
- Nuclear pore complex protein Nup155
- Nuclear pore complex protein
- 54 kDa nucleoporin
- Nuclear pore complex protein Nup214
- Nuclear pore complex protein Nup133
- mRNA export factor GLE1
Sequence:
MSHRRSRSGSPSGPVRSCTNSQNPRDMERRIFVGNLPTSLMDRKDMEELFSPYGKIHALSMFQGYGFVQFERVEDAEAAKAGQNGRPYKGYKIAINMAAERQRQNKAQSRPSPPRRDPYGGYGEGREPRPRSRSPMHGRDSRAHRGSREHSREPGREPRHPRDHHEPRDPNFDRYRTPEGRDKDLRGEPRGEPRGDPRDPTFREEGYDRYYRGGADEHHRKKDDPYRDPWNGRREPEDDRVRVEERRRNELYRQYYEEVQRQYDRERPVDCSVIVVNKAQNREYAETVGRKVRDLGMVVDLIFLNTEVSLTQALEDVGRARTPFAIIITQQHQVHRSCTVNILFGTPQEHRNMPMEDAMVLVGHNYDSFKVEHREKEREEIAQKAAKMADDVLMREHEREGHPVTLLPAITLLSEGRFLTPEELDSLIEYLRVKRERIVRADPLAAVHPPATAATHDPPLQAQTMPPAVHPGHAPPPHSAHSTHMSMPPAPNATNNQQELQAKILSLFNSGAGASASAASPAMVPQSYGSTMGIQSTGLPMSSASPVPKMAPTPSQVPNMMGARPPMRPGPVPLGIHQGYGSPTGRMAAPQGGQRPPVSGGAGINFDNPSVQKALDTLIQSGPSLNHLVNAGNSASPRPSHGMGQGMGQNMGQGMGQGMGQGMGQPPPMAMYPRHY
Protein: Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (mMED25) (Q8VCB2)
Organism: Mus musculus (Mouse)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for RARA/RXRA-mediated transcription (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 23
- Mediator of RNA polymerase II transcription subunit 28
- Mediator of RNA polymerase II transcription subunit 1
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 24
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 15
Sequence:
MVPGSEGPARAGGLVADVVFVIEGTANLGPYFEELRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPADVSQDPRHMVLVRGLVLPVGGSSTSGSLQTKQAVPLPPAPASAATLSAAPPQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKSQKAGLGPRFSPINPLQQAAPGVGPPFSQAPAPPLAPVPPGAPKPPPASQPSLVSTVAPGPVLAAPAQPGAPSLAGTVTPGGVNGPSAAQLGGPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPVLGPILEEQARPPQNLLQLRAPQPQPQGAVGASAATGQPQPQGATQAPTGAPQGPPGAAPGPPPSGPILRPQNPGANPQLRSLLLNPAPPQTGVPPPQASLHHLQPPGAPTLLPPHQSMGQPQLGPQLLHPPPAQSWPTQLPQRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI
Protein: Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) (Q91ZQ5)
Organism: Mus musculus (Mouse)
Function: Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore. Essential for the production of 11-cis retinal for both rod and cone photoreceptors. Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:A9C3R9}. Cell membrane {ECO:0000250|UniProtKB:Q28175}; Lipid-anchor {ECO:0000250|UniProtKB:Q28175}. Microsome membrane {ECO:0000250|UniProtKB:Q28175}. Note=Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated. Undergoes light-dependent intracellular transport to become more concentrated in the central region of the retina pigment epithelium cells (By similarity). {ECO:0000250|UniProtKB:Q16518, ECO:0000250|UniProtKB:Q28175}.
Interaction partners:
- Lecithin retinol acyltransferase
- Retinol dehydrogenase 5
- Retinol dehydrogenase 11
- Retinol dehydrogenase 10
- Retinaldehyde-binding protein 1
- Diacylglycerol O-acyltransferase 1
- Acyl-CoA wax alcohol acyltransferase 2
- Rhodopsin
- Bestrophin-1
- Retinal-specific phospholipid-transporting ATPase ABCA4
Sequence:
MSIQIEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFKGVEVTDNALVNIYPVGEDYYACTETNFITKINPETLETIKQVDLCNYISVNGATAHPHIESDGTVYNIGNCFGKNFTVAYNIIKIPPLKADKEDPINKSEVVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNESMGVWLHVADKKRRKYFNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKRNAMKAPQPEVRRYVLPLTIDKVDTGRNLVTLPHTTATATLRSDETIWLEPEVLFSGPRQAFEFPQINYQKFGGKPYTYAYGLGLNHFVPDKLCKMNVKTKEIWMWQEPDSYPSEPIFVSQPDALEEDDGVVLSVVVSPGAGQKPAYLLVLNAKDLSEIARAEVETNIPVTFHGLFKRS
Protein: Transcription factor AP-2-delta (AP2-delta) (Activating enhancer-binding protein 2-delta) (Transcription factor AP-2-beta-like 1) (Q7Z6R9)
Organism: Homo sapiens (Human)
Function: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor AP-2-alpha
- Transcription factor AP-2-beta
Sequence:
MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKTSEAAVKEGKTEKTD
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Q7JW61)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- LD31543p
- Centriolar coiled coil protein 110kDa, isoform B
- Ubiquitin carboxyl-terminal hydrolase
- Roundabout 1, isoform A
- Ubiquitin carboxyl-terminal hydrolase
- FI19924p1
- Ubiquitin carboxyl-terminal hydrolase 16/45
- Kurtz arrestin
- GH17761p
Sequence:
MSLSSNPNPHNPYVEHRNRTIHSSQGHTLANGYAMGDPRSSRCHDKLFSGSLKSLARREDSNASDSEGTDTAKGSGTGLVGLQNIANTCYMNSALQALSNLPPMTHYFINCSDLVEYIAEQSARRCKPGGLAKSYRRLMQEIWQDVDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEFLRCFMDQLHEELTEQVSMLPQTQNQPQYQSLQQQQPSETDDENDDEAAPASLSHASESEYDTCESSMSERSAEVLLKTEYFVTPCRTNGSNSGLPEGHSVQLQQAPLQHQQKNASSAEQKPIEAARSIISDVFDGKLLSSVQCLTCDRVSTREETFQDLSLPIPNRDFLNVLHQTHSLSVQSLNAAETSARTNEGWLSWMWNMLRSWIYGPSVTLYDCMASFFSADELKGDNMYSCERCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLSYSSKISSDVYFPLEGFDMRPYIHKDCKSEVAIYNLSSVICHHGTVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQSCQAYVLFYHKHNPQMKLVRDEAMTLSTSHPLCDSDIQFYITREWLSRLATFSEPGPINNQEMLCPHGGILHSKADVISQIAVPISQPLWDYLYRTFGGGPAVNIIFECEICKRAAETLSRRQQYELNEFTKYNGLQNEFDSTAIYAIAMPWLRSWQQFSRGKTHKDPGPITNEGIAAPTENGSATVSCVRLGSDYAQLNARLWRFLHNIYGGGPEIILRQALSDEDDAEEIEIIDQDDECDDDEDQDLEGEGEDEEIAAASYQHNHSDTESNLGIRNTPSPSPSTSPSPSLTGTRQPMETESDLRPSSSKSKRSRSKMKVSALRLNMRNRGKRNRSAFKQYAEMFGAKGNYNAHSNAEPVVSEKDEKDKDNDRTVAFPSEYSLPISIPFQSDNFQVNGVHEKSRDKGKLRNSSKSGSTAATKENVTLQKFVTLREANGPSDETDI
Protein: B-cell CLL/lymphoma 11A (BAF chromatin-remodeling complex subunit BCL11A a) (BCL11 transcription factor A a) (Q1RLR5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- HBS1-like protein
- Hemoglobin subunit beta-1
Sequence:
MSRRKQGKPQHLSKRDFSPEPLSAVVSEERQEQRGLVQVAPEGDQDLLTCGQCQMNFPLGDILIFIEHKRKQCNGTLCMDKAVDKPPSPSHGELRRASNPVEVGVQVTPEDDDCLSTSSRGICPKQENITGKDEPSSYTCTTCKQPFSSAWFLLQHAQNTHGFRIYLESERGSPLTPRVGAPSGMGADCSSQPPLHGIHLPEGSPFNLLRIPNSGRDGPPLREGRFPPTPPLFSPPPRHHLDPHRMEHLSPEELALATHHPSAFDRVLRLNPIPMDPPAMDFSRRLRELAGNTSGSTPPLSPNRPSPMQRLLQPFQSGTKPPFLSTPPLPSMQSPSGSQSTPTPLNQQSNTPMKTKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCHLCDHACTQASKLKRHMKTHMNKSSPTTVKSDDGLSTASSPEPGTSDLVGSASNALKSVVAKFKSENDRMIPENGEEEEEEEEEEEEEEEEEEEEEEGEEEELERERERERERERERDRDGGRNNYHFSLNLQAARHHENNGGRLGEDGIPRSLPEVMQGMGLAASMQHYSEAFHQHKRGALNSDNDAHRDMCDEDSALESDRVDEGCGSAINGRGSSPSESASVGLSKKLLLGSPSSLSPFSKRIKLEKDFDLSTPTIPNTENVYSQWLAGYAASRQLKDPFLNFGDSRQSPFASSSEHSSENGSLRFSTPPGDLDGGVSGRSGTGSGGSTPHLGGPGRPSSKDGRRTDTCEFCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICQMPFSVYSTLEKHMKKWHSDRPLSTEIKTE
Protein: Pannexin-1 (PANX1) [Cleaved into: Caspase-activated pannexin-1 (Caspase-activated PANX1)] (Q96RD7)
Organism: Homo sapiens (Human)
Function: Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Plays a critical role in oogenesis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20944749, ECO:0000269|PubMed:30814251, ECO:0000269|PubMed:30918116}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16908669}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}.
Interaction partners:
- P2X purinoceptor 7
- Pannexin-2
- P2X purinoceptor 4
- Caspase-1
- Caspase-7
- Gap junction alpha-1 protein
- Caspase-3
- Magnesium transporter MRS2 homolog, mitochondrial
- P2X purinoceptor 1
- Voltage-gated potassium channel subunit beta-3
Sequence:
MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLGQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQRLLDSSC
Protein: Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71) (Q9BRP4)
Organism: Homo sapiens (Human)
Function: Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 10
- 26S proteasome regulatory subunit 8
- 26S proteasome regulatory subunit 6B
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 12
- 26S proteasome non-ATPase regulatory subunit 14
- 26S proteasome regulatory subunit 7
- Proteasomal ubiquitin receptor ADRM1
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 3
Sequence:
MAAPLRIQSDWAQALRKDEGEAWLSCHPPGKPSLYGSLTCQGIGLDGIPEVTASEGFTVNEINKKSIHISCPKENASSKFLAPYTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSACLGVLADCGSSINGVAVGAADNSINLGSPEQMPSEREVGTEAKMLLLAREDKKLQCLGLQSRQLVFLFIGSDAFNCCTFLSGFLLLAGTQDGNIYQLDVRSPRAPVQVIHRSGAPVLSLLSVRDGFIASQGDGSCFIVQQDLDYVTELTGADCDPVYKVATWEKQIYTCCRDGLVRRYQLSDL
Protein: At5g19875 (Transmembrane protein) (Q8L9M7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MARSPYYGSSYLDYLSLPNPHLCFLFIVVFFVLSFTWYLNFESIIEDTLDHLKLVFIFTPLFLLLLVHFFSGGLSFYVPWPEQDSIHRAGSSPWGVAAVLVLILFMVSYQSDFQERWFPFGAK
Protein: ATP-dependent RNA helicase (EC 3.6.4.13) (Q9VX34)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- EG:8D8.4 protein
- LD31322p
- Probable ATP-dependent RNA helicase pitchoune
- Eukaryotic translation initiation factor 4E1
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- eIF-4F 25 kDa subunit
- Nucleolar MIF4G domain-containing protein 1 homolog
Sequence:
MQRQKPKGPGKPGSRFKPGSGTFKGAGGGRKSGDNSQKRPRQEINKSRLAATEAEIQDLKTKYAEIDATAIKKFAQFPLSKKTQKALAESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLFMNKWSRTDGVGAIIISPTRELAYQIFETLKKVGKHHDFSAGLIIGGKNLKFERTRMDQCNILICTPGRLLQHMDENPLFNTSTMEMLVLDEADRCLDMGFQKTLNSIIENFPPVRQTLLFSATQTNTVQDLARLNLKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPELLQQSYVVLNLEDKITMLWSFIKNHLKQKIIVFVASCKQAKYLYEIFCKLRPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVLTPSEEEYMISALKEQLNIDIRCVQIDPKKLFSPRVKIEAFLAQFPELRATAQRAFLSYIKSVFLMRNKRLFNVFSLDLDAFAQSLGLAVTPRVPFLEKFLWRQKQLQQQKEQGDNAKSINPLLSKLTKQQSFGGGDEDEENSDDEDFIKVKRKDHDVEGEPVKLDEEDDTENEAEAPLVVPKREKLVTKASLAKKALKKNLQVNSKLKFDDEGETMADDRSQMKALSARQRTVNQDDDDGGINLVLSKALLTEEDQYDKQRFRELVKKRHKLQREKLRKKAEEAKGSDDEEEQQDDDNADDAGSESDHSVDLSWLPDPDKVYKNKPNASDRNESKSESSDASDDEKADDSDGDDDDVSDDEPAYKKSKLTNKMTLMDTEAIAASLLGS
Protein: Protein lin-32 (Abnormal cell lineage protein 32) (Q10574)
Organism: Caenorhabditis elegans
Function: Probable transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3'. Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. Required for specification of cell fate, acting in concert with lin-32, in the development of the male-specific genital sensilla (simple sense organs) known as rays. Involved in regulating glial specification, perhaps by suppressing a glial fate in different lineages during early embryogenesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:31386623, ECO:0000269|PubMed:7800042}.
Interaction partners:
- Helix-loop-helix protein 14
- Helix-loop-helix protein hlh-2
- Transcription factor unc-86
- Helix-loop-helix protein lin-22
- BHLH domain-containing protein
- Homeobox protein mab-5
- Paired box protein 6 homolog
- Homeobox protein vab-15
- Stork-head box protein ham-1
- Homeobox protein egl-5
Sequence:
MSWEQYQMYVPQCHPSFMYQGSIQSTMTTPLQSPNFSLDSPNYPDSLSNGGGKDDKKKCRRYKTPSPQLLRMRRSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQILKQDSKNENLKSKSG
Protein: phosphoribosylglycinamide formyltransferase 1 (EC 2.1.2.2) (Q9I184)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- L-ornithine N
- Pyoverdine biosynthesis protein PvdE
- Pyoverdine synthetase D
- PvdJ
- Phosphoribosylformylglycinamidine synthase
- Ferripyoverdine receptor
- L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH
- PvdL
- PvdP
- Acyl-homoserine lactone acylase PvdQ
Sequence:
MTKRKLAYIWSLRNAAADKAGQYVPYKGEQRYMKSVLESLVEALNQTALGDAYELVGVIYDDDAELPRDQGKIKDYGFAYRPGQQWFYPADLQVQGKTLNDLLLSVPSTYRRYPRGTPEHVAGKSDFERRLHDTLVELGADVVVLDGLLVILDELVRPGAPFARRIMNIHPGVTREDSPYERRGAYATLDALYGARGEKVVDWATMEKVAVEPLYWTGASFHYVDNGIDSGEVFHDVLKTEISPDDTILELRWNNFNNSLFPALHEGLALLAEKL
Protein: Trivet, isoform E (A0A0B4KHB5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLAMPTLMMPATAQMTLSAAHGKPYETKLLAIHQTHLQQQQQQQAPAPPQQQQQVQQSQQQAPNGKQQSQQMTIVTTQQQQQQQHPQSQSPHQQQQSQQQAAAAAAAAAAAAHHQQQQAVAAAVCAAQQQAVVVQQQQQQQYQIHSQQQSPQQQQVLCISPKQEQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVTPAAASAAAVQNQFLQGIQGYHFGQYGGYQQGYMGMGVQIPATWQGVTQAQISPAQQLATGVAGTAIPQAAGVVAYPIQQFQVSPQLPDEEWLAANLLC
Protein: Putative phosphoribosyl transferase Rv0571c (P9WHK1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized protein Rv2004c
- Vitamin B12-dependent ribonucleoside-diphosphate reductase
- Uncharacterized glycosyl hydrolase Rv2006
- Uncharacterized protein Rv2003c
- Probable cation-transporting ATPase F
- Putative zinc metalloprotease Rip3
- Probable protein archease
- Probable polyglutamine synthesis accessory protein Rv0574c
- Putative NAD
- RNA-splicing ligase RtcB
Sequence:
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVVCLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPVPVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLATQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGTLEQVAKLACDWFIDHLCGPGPSG
Protein: Recombination-promoting nuclease RpnA (EC 3.1.21.-) (P31667)
Organism: Escherichia coli (strain K12)
Function: A low activity DNA endonuclease yielding 3'-hydroxyl ends, equally active on ss or dsDNA, not active on dsRNA. Shows no sequence specificity. Upon expression enhances RecA-independent DNA recombination 49-fold, concomitantly reducing viability by 88% and probably inducing DNA damage as measured by induction of the SOS repair response in RecA cells. RecA-independent DNA recombination leads to replacement of recipient genes with large segments of donor DNA rather than DNA addition to the donor strain; increased expression of RpnA leads to smaller replacement segments, suggesting this protein may play a role in generating crossover events.
Interaction partners:
- HTH-type transcriptional regulator MalT
- Diaminopropionate ammonia-lyase
- 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenasepropanoate dehydrogenase)
- Probable [Fe-S]-dependent transcriptional repressor FeoC
Sequence:
MSKKQSSTPHDALFKLFLRQPDTARDFLAFHLPAPIHALCDMKTLKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAAMQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPKLARQLYASAFPLIDVTVMPDDEIMQHRRMALLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQTGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLADIMRFTGLSEEELAAASQ
Protein: Adiponectin receptor 2 (Q3YAF7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MNEPTEHRLGCTRTPEPDIRLRKGHQLDDTRGGNNDNHHGDLEPSLETPVCSSYYENSPEELECHDDNSQEDEGFMGMSPLLQAHHAMERMEEFVCKVWEGRWRVIPHDVLPDWLKDNDFLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGCVFFLCLGIFYMFRPNISFVAPLQEKVVFGLFFLGAILCLSFSWLFHTVYCHSEGVSRLFSKLDYSGIALLIMGSFVPWLYYSFYCNPQPCFIYLIVICVLGIAAIIVSQWDMFATPQYRGVRAGVFVGLGLSGIIPTLHYVISEGFLKAATIGQIGWLMLMASLYITGAALYAARIPERFFPGKCDIWFHFHQLFHIFVVAGAFVHFHGVSNLQEFRFMIGGGCTEEDAL
Protein: Transporter, putative (Q38BH0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MASQGETVSSPICVSNRIASTGLVGLEVGATSPVRDRAHQGGARVRLDRGLRECEDAGEVPCFNTRIGAKTTLSAISELLELKTDAGLSLTEAQECLVRRINFIRRHYIYLHAAYIMLIALTGATALCYTEDNLAFVDALFAAMSAVCCCGLSTVEVAEWKAETHAFLHVMMLAGGAILTSAYQPLLRLWAVSKLCPMLEGDTKDSDGGNALGGNYLSKSMRLWYASALCVVTTLMYVILVHISLAFFLGMFNRSNLRVPDVVLLAVASFHGAIFTPMEPYVDDPAVVAVASVGCALGFTMFPVLLRCFLRMEWFFFSGVKRLFSSFRQTSTVRQRSLFPADNGEEAALLGCVDVPLKKGAKEGEFEGGVKGYSTWDRAFCDILKSKQPASMHTFLFDLRETVYLGVAWVVITVIAAAPFWFQQWSGDGLLAPYSAPYKVFLALCQAAIVRFGGASFLSCLDYSDSHIAITIMAMYVPPIPVPTYRVYKKWKSVPLAYAIRPFTSRKFWLFVAVFCILIFEEEWPDGPDAPYYDMITRTMFEVVSAFSGCGLSLPPRWSALSFSGTLGVFSKLVIVAVMFAGRHYTVDFSIDIGFNSLP