wanglab/gogpt-training-data huggingface dataset:
Protein: Cytoplasmic protein 89BC (Q7KJ37)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000256|ARBA:ARBA00004436}.
Interaction partners:
Sequence:
MEAYRFDSSALERAADAAKTLERSKHAREALELSKMQEATRQTEYNTKVKEYEAHIEQAKVEQKRIDHEERRKTLIEETKQQQQRAQYQDQLSRKRYEDQLLQQQRVQEENLRKQEESVQRQEAMRRQTIEHEIEMKEKNRLKLLEHELRAKARVDRENRDINLEKIRLKAQEHRTTVLEGIKTAGTVIGAGAEAMLTDWDKVLTAAGGLSLLALGVYTAKGATGVVSRYVEARIGKPTLVGETSRFAFLDALKNPLHYLKRLRAKPTDALQGVVLNPKLEERLRDIAIATKNTRINKGMYRNVLMHGPPGTGKTMFAKKLAEHSGMDFAIMTGGDVAPMGKEGVTAIHKVFDWSHTSRRGLLLFVDEADAFLRKRSSEKISEDLRAALNAFLYRTSEQNPKFMLVLASNTPEQFDYAINDRLDEMVEFTLPGLEERERLLRLYFDKYVLQPAAAGAKRFKLDTFDYGKTCSKMAALCEGMSGREISKLGVSWQAAVYASEDGLLTEKMVLDRCYSAAQQHKQKMAWLSDQERADHKSITGTAAPPLTLTAKKL
Protein: Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (EC 3.6.5.-) (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas) (Q5JWF2)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:27120771}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q63803}. Apical cell membrane {ECO:0000269|PubMed:27120771}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Parathyroid hormone/parathyroid hormone-related peptide receptor
- Corticotropin-releasing factor receptor 1
- Thyrotropin receptor
- Adenosine receptor A2a
- Vasopressin V2 receptor
- Growth hormone-releasing hormone receptor
- 5-hydroxytryptamine receptor 7
- Glucagon-like peptide 1 receptor
Sequence:
MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
Protein: Proteasome subunit beta (EC 3.4.25.1) (20S proteasome beta subunit) (Proteasome core protein PsmB) (Q6LZD4)
Organism: Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL)
Function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02113}.
Interaction partners:
- Proteasome subunit alpha
- Proteasome-activating nucleotidase
- Large ribosomal subunit protein eL40
- CDC48 cell division cycle protein family member
- Tetrahydromethanopterin S-methyltransferase subunit A
- Transcription termination factor FttA
- Leucine--tRNA ligase
- Conserved hypothetical archaeal protein
Sequence:
MISNSEYHKEYMKGTTTVGLLCNDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQSLIRLISAEAKIYKMRTGNNMTPLSCTTLISNVLHGNRHYPLLTQLILGGYDLINGAKLFSLDPVGGINEESSFTATGSGSPTAYGVLESEYKSDIAIEKGLLIAVKALSSAMQRDAYSGNGISLAHINKDGVKLYSDAEIEGFLKKINRKR
Protein: Nicotinic acetylcholine receptor alpha7, isoform E (E1JJR2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
- Nicotinic acetylcholine receptor alpha5, isoform I
- Nicotinic acetylcholine receptor alpha6, isoform E
- RIC3 acetylcholine receptor chaperone, isoform C
- Wing blister, isoform B
- Acetylcholine receptor subunit alpha-like 1
- Proteasome subunit beta
- Nicotinic acetylcholine receptor alpha4, isoform C
- Nicotinic acetylcholine receptor alpha3, isoform B
- Acetylcholine receptor subunit alpha-like 2
- Locomotion-related protein Hikaru genki
Sequence:
MKKPSRSRPDNPSCPGQDRTRSMSFPQPHSLPEATANGGRMLVYGLGLLIMIPACAAGPHEKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDEAGGDISSFITNGEWDLLGVPGKRNEIYYNCCPEPYIDITFAILIRRKTLYYFFNLIVPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNPDTHEMSEWIRVIFLYWLPCILRMQRPGQVGYECPPPPSSSSSSASGEKKQQIQNVELKERSSKSLLANVLDIDDDFRCNHRCASATLPHQPTYYRTMYRQGDDGSVGPVGPAGPVVDGRLHEAISHTCLTSSAEYELALILKELRWITEQLKKEDETSDITRDWKFAAMVVDRLCLIIFTLFTIIATLAVLFSAPHFIVSGVRG
Protein: Dehydrin ERD10 (Low-temperature-induced protein LTI45) (P42759)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Dehydrin Xero 2
- Low-temperature-induced 78 kDa protein
- Protein COLD-REGULATED 15A, chloroplastic
- 1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal
- Protein EARLY-RESPONSIVE TO DEHYDRATION 7
- Stress-induced protein KIN1
- Probable desiccation-related protein LEA14
- Dehydrin HIRD11
- Stress-induced protein KIN2
- Protein COLD-REGULATED 15B, chloroplastic
Sequence:
MAEEYKNTVPEQETPKVATEESSAPEIKERGMFDFLKKKEEVKPQETTTLASEFEHKTQISEPESFVAKHEEEEHKPTLLEQLHQKHEEEEENKPSLLDKLHRSNSSSSSSSDEEGEDGEKKKKEKKKKIVEGDHVKTVEEENQGVMDRIKEKFPLGEKPGGDDVPVVTTMPAPHSVEDHKPEEEEKKGFMDKIKEKLPGHSKKPEDSQVVNTTPLVETATPIADIPEEKKGFMDKIKEKLPGYHAKTTGEEEKKEKVSD
Protein: Staufen double-stranded RNA binding protein 1 (F6UDC6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MCEVSRGWKPCTEGILKVRPTRKISYEESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE
Protein: Structural maintenance of chromosomes protein (Q9VXE9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005719}.
Interaction partners:
- Nipped-B protein
- Structural maintenance of chromosomes protein
- FI11703p
- Precocious dissociation of sisters 5, isoform A
- LD34181p
- Protein wings apart-like
- MAU2 chromatid cohesion factor homolog
- N-acetyltransferase eco
- Stromalin-2
- separase
Sequence:
MHIKQIIIQGFKSYKDQTVVEPFDKRHNVVVGRNGSGKSNFFYAIQFVLSDEFTHLRPEQRQSLLHEGTGARVISAYVEIIFDNSDNRVPIDKEEIFLRRVIGAKKDQYFLNKKVVPRNEVVNLLESAGFSSSNPYYIVKQGKINQMATAADSYRLKLLREVAGTRVYDERKEESLNLLRETDSKVEKISEYLKTIEDRLQTLEEEKEELKEYQKWDKTRRTLEYIRYETELKDTKKALDELQLQRKSSSDKKKIYNIEIQKAQEKIKDVQKNLKEAKKKVQSTKEERSVLMTEQQQLLREKTKLDLTIVDLNDEVQGDNKSKERADQELKNLKVTIAEREKELDDVKPKYEAMKRKEEDCSRELQLKEQKRKELYAKQGRGSQFSSREDRDKWITNELKSISKQTRDKIAHHAKLVEDLKKDATSEKDLGQKIEEHSSELEQLRLQIDEHNKKYYELKKTKDQHQSMRNELWRKETQMTQQLQTHKEELSRADQALRSMAGKPILNGCDSVRKVLDSFVERGGQSAEIARAYYGPVIENFSCDKTIYTAVEVTAANRLFHHIVESEYEGTQILKEMNKLKLPGEVTFMPLNRLQVKIHDYPDDPDSIPMISKLKYDEQHDKALRYIFGKTLICRNLERATELAKSTGLDCVTLDGDQVSSKGSLTGGYFNTSRSRLEMQKKRTEYTSQIAEFEKKLSKLRNELKSTENNINSIVSEMQKTETKQGKSKDVFEKVQGEIRLMKEELVRIEQYRAPKERSLAQCKASLESMTSTKSSLEAELKQELMSTLSSQDQREIDQLNDDIRRLNQENKEAFTQRMQFEVRKNKLDNLLINNLFRRRDELIQALQEISVEDRKRKLNNCKTELVSAEKRIKKVNSDLEEIEKRVMEAVQLQKELQQELETHVRKEKEAEENLNKDSKQLEKWSTKENMLNEKIDECTEKIASLGAVPLVDPSYTRMSLKNIFKELEKANQHLKKYNHVNKKALDQFLSFSEQKEKLYRRKEELDIGDQKIHMLIQSLEMQKVEAIQFTFRQVAQNFTKVFKKLVPMGAGFLILKTKDNEGDEMEKEVENSDAFTGIGIRVSFTGVEAEMREMNQLSGGQKSLVALALIFSIQKCDPAPFYLFDEIDQALDAMHRKAVANMIHELSDTAQFITTTFRPELLENAHKFYGVRFRNKVSHIDCVTREEAKDFVEDDSTHA
Protein: CHK kinase-like domain-containing protein (O61882)
Organism: Caenorhabditis elegans
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase 1
- Aryl hydrocarbon receptor protein 1
Sequence:
MSTKPLSILQPGTGLFNTHVTLEDVNKAIKEQMSTESELTAESKMEVIGEGNGFSSCVILITCHWTIPSSHLPKKLILKIVSFVHVQGLLNKSNEEGNSVMSPEEEAHVHAHFEKSCQKGHNLEVEFCEAFGHLEGLLLPKVFFSQKFEEDNPNKGFVGMEFVEGSVVRHCYENVTVDELQPILKALARLQALSLSTESCRNLDNGEAFEESLMDMLSEDGLKGIFDQSRNIDQKLSEKVERIEQNHKEILNLETVLNLNKVVGIDQKVICHGDLWAANILWTQTDGGFIADKVLDYQESHMGNPAEDLVRLLVSTISGADRQSHWEHILEQFYTYFTDEIGSNNAPYTLEQLKTSFKLYFPVGALTLISLFGPAVDMKLQGMESGKAENYRRIVIEKVDCLLDDVLNFHDFNKKFTGKN
Protein: Serine/threonine-protein phosphatase PP2A-1 catalytic subunit (EC 3.1.3.16) (P23594)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Exact function not known, phosphatase 2A performs an essential cellular function.
Interaction partners:
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
- Type 2A phosphatase-associated protein 42
- Protein phosphatase PP2A regulatory subunit A
- Protein phosphatase PP2A regulatory subunit B
- Serine/threonine-protein phosphatase PP2A-2 catalytic subunit
- Anaphase-promoting complex subunit 1
- Cell cycle serine/threonine-protein kinase CDC5/MSD2
- DBF2 kinase activator protein MOB1
- Protein phosphatase methylesterase 1
- Serine/threonine-protein phosphatase 2A activator 2
Sequence:
MDTDLDVPMQDAVTEQLTPTVSEDMDLNNNSSDNNAEEFSVDDLKPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPSVSRKTPDYFL
Protein: ABC transporter C family member 6 (ABC transporter ABCC.6) (Q8T6H3)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
Sequence:
MFTKILKKFFSSYEKLKDNEDENEPSSNSTNNFYKTCPEDNSSKWSKISFNWVTKLIMKGYLKESLEMNDIYDLPELNKVQTTSKLLEDIDLSNNSNYTLIKHIYKKFLPKNKYALVSNLFIIIFTFLSPICLKFLINYISIQDENEKSILKGILLCCLLCLCVLGQSISQELFYWFGIKNGFDVRGALAAKIFEKTLKLSNASRKEYKSGKIMNIMSIDVANISEYFWTHHINIVSHFIQILSLVGLLCYVVGPSGLVGFGVMVIALPINAMLCAKSSNYLEKSLEYSDSRTNLTSELITNIRPFKMYAWENFFINKIDGQRKQELKNIFLRIFYSILDHMMIETNATLVLVSTFATYSLNGNTMSLDVTFTAMTIFSKLEVPLIRLPYDIFKAIGLIPSVKRVQNFLKSSESLKYNKNFKNENQKITTTKENNNQHGQDNDIIVENCTFQWNEPENNNIFELNYGDNEEEENQDESINKKENDNEEFNYKLKDINLIVPKGKLTMICGVVGSGKTSLIFGLIGEIYKLNGSVSGVPNNISFTSQQPFLLSASLRENILFGNEFDIERYKKVIESTALTKDIVNLAGLDLTEIGERGINLSGGQKQRISLARALYANSDCFIFDEPLSAVDPEVASHLFDHCIQGELMRNKTRILVTHQLQFIPYADHIIVLNSNGQLIQGTYQELNEKGIDFKSILKTKEIKKNVENETDSEELIKNEIEIENEIIDVNNAISDKNDPNLIEKAKLLVKEDKNEGEVEFNVYKKYFSYGSSGVTLFITISLFFVGQAIFKVSDFWLTIWTERSIEGKSDSFYIGYYLLIFGTFVVILMIRILLLCRITFNVGKNLHSALLKSVTYASCRFFDTNPSGRILNRFSKDTSDIDIHMFDILTEVSMCFSELTIGLISIVFIIPIMVIPLIILSIAYYILQRLYRPSARELNRWESITVSPIFSLLQECYNGLLTIRTYKQESRFIKEMFDNININLGCFFYSFAVHRWVSMRLEVMGWIMVFFTSLIATLFISNNGLAALSVTTALSLNGYLSWGIRRIVDLEVKMNSFQRIQSYIEIPKEGNKLVSTNSNEVDNHTIKDADLVNWPNKGIIEFKNVEIKYRPNSEPNLKDLSFKVQSSEKIGIVGRTGAGKTTIASSLFRMVECSKGLILIDGIDISKVQLQKLRSSIGIVPQDPFIFTGTIRSNIDPFNEFTDFEIWESVEKVKLKDAINSMPLKLETALQENGDNGFSYGQKQLLCLCRTILKNFKIILMDEATSSIDYHTAQLIKQTIQENFKDCTTLTIAHRLETIIDCNKIAVIDSGQLIEFDTPSNLMNIPNSKFNKLIKSQTDYNNNEKTIINK
Protein: ER membrane protein, putative (DUF962) (Q9CA70)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At2g35730
- Probable protein phosphatase 2C 40
- At5g47730
- Fimbrin-2
- Dirigent protein 7
- Leucine-rich repeat receptor-like tyrosine-protein kinase PXC3
- Classical arabinogalactan protein 7
- UDP-glycosyltransferase 71C3
- EG45-like domain containing protein 2
- Peroxidase 47
Sequence:
MSNRIGLLDLEKHFAFYGAYHSNPINIIIHTLFVWPNVFATLLFLYSTPPILDHSQLGFLKSLTFDGVLRLDIGFTLTVTYAVFYICLDKKSGVLAALLCFSCWIGSSFLAARLGHSLTLKVGVASQLLCWTGQFLGHGLFEKRAPALLDNLLQAFLMGPFFVLLEVLQSVFGYEPYPGFKARVDSKIESGIKEWREKKKQQQMKKVT
Protein: Mineralocorticoid receptor (Nuclear receptor subfamily 3, group C, member 2) (A6YIH7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- peptidylprolyl isomerase
- Corticotropin-releasing hormone b.
- Prostaglandin E synthase 3
- Glucocorticoid receptor
- 11-beta-hydroxysteroid dehydrogenase type 2
- Angiotensin-converting enzyme
- Corticotropin releasing hormone receptor 2
- Peptidylprolyl isomerase.
Sequence:
METKRYQSCCEGAKAENKWAQMPNTADYICSAEESLTNSDVLMDIVNSSNTPNVQSICKDNNFKNTEATMIRVNQNQPLPFPTFNNCFNNRKSETDSKELSKTVAESMGLYMNAAREADFGFSQQGAAGGQGSPGKLYPLCGRTNEDSQAKTSGSPKMKAPPASFPPGAQLPNGGPQECAVVSDSVPSALVTALSSSTDGSCPMSSPTGHNMVSSTTSPTYFDSDCPTLDSATSSLTHCQHTSPNICSPVKSSIVGSPPLPSPLSVMKSPVSSPHSIGSVRSPLSCNTNMRSSVSSPTTNGGNTCNIKPSISSPPTAGSMSMSSPRNSSRGFSVSSPPSGLGLVQNDVNSPESREHDFKGFEFPKVENVDGEIFNIGLDAMGVAKYIKNEPGTDFRSMCLGSSKSAMSNSPFVTHIKTEPNREVTCSNLQFAEPQHSLGCFPSTETTYLSLRDNIDEYSLSGILGPPVSSLNGNYEPGVFPNNGLPKGIKQETNDGSYYQENNNVPTSAIVGVNSGGHSFHYQIGAQGTMSFSRHNLRDQTNPLLNLISPVTGLMETWKTRPGLSQGPLTARGDGYPGAVCLTENMESASLRHTSSTAKVCLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRVRKCLQAGMNLGARKSKKLGKIKSISEDSSLQSSKDGPFLTSEKELSSSTALVPHTPTVAPYLTPSVCSVLELIEPEVVFAGYDNTQPDTTDHLLTSLNQLAGKQMIRVVKWAKVLPGFRSLPIEDQITLIQYSWMCLSSFSLSWRSYKHTNAQMLYFAPDLVFNEERMQQSAMYDLCVGMRQVSQEFVRLQLTYEEYLAMKVLLLLSTVPKDGLKNQGAFEEMRVNYIKELRRSVGKATNNSGQTWQRFFQLTKLLDATHDLVRSLLDFCFYTFRESQALKVEFPEMLVEIISDQIPKVESGQTHTLYFHKK
Protein: Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.141) (Heme O synthase) (Q8CFY5)
Organism: Mus musculus (Mouse)
Function: Converts protoheme IX and farnesyl diphosphate to heme O.
Subcellular location: Mitochondrion membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Heme A synthase COX15
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase assembly protein COX11
- Holocytochrome c-type synthase
- Ferrochelatase, mitochondrial
- Surfeit locus protein 1
- Cytochrome c oxidase subunit 6B1
- Cytochrome c oxidase subunit 5A, mitochondrial
Sequence:
MAASPHTISSRLLTGSVGGCIWYLERRAIQGLPHRVTRLFRNVSNQWVTLQHLSFLKRMYVTQLHRGLSQRVKPKPEPPASPFLEHTSSGQARADEDELPSFPAPSRPLSRKPNEELVELEATSIVDHSLDTAKEKKEERQWKEMKLHTDDLPGILARLSKIKLTALVVSTTSAGFALAPGPFDWSCFLLTSLGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVALLTWGVNPLTGALGVFNIFLYTCCYTPLKRVSITNTWVGAVVGAIPPVMGWTAATGSLDAGALLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPALCRRVALRHCLALIALSTAAPVLDITTWVFPVISLPINLYISYLGFRFYVDADRRSSRKLFFCSLWHLPLLLLLMLTCKQRPGQEGDKGEAPS
Protein: AMP deaminase 1 (EC 3.5.4.6) (AMP deaminase isoform M) (Myoadenylate deaminase) (Q3V1D3)
Organism: Mus musculus (Mouse)
Function: AMP deaminase plays a critical role in energy metabolism.
Interaction partners:
- Adenylosuccinate lyase
- Adenine phosphoribosyltransferase
- Adenylosuccinate synthetase isozyme 2
- Adenylosuccinate synthetase isozyme 1
- Adenosine kinase
- Bifunctional purine biosynthesis protein ATIC
- Inosine triphosphate pyrophosphatase
- Inosine-5'-monophosphate dehydrogenase 2
- Inosine-5'-monophosphate dehydrogenase 1
- Hypoxanthine-guanine phosphoribosyltransferase
Sequence:
MPLFKLTGQGKQIDDAMRSFAEKVFASEVKDEGGRHEISPFDVDEICPISLHEMQAHIFHMENLSMDGRRKRRFQGRKTVNLSIPQSETSSTKLSHIEEFISSSPTYESVPDFQRVQITGDYASGVTVEDFEVVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEALVGNESFYPVFTPPPKKGEDPFRTEDLPANLGYHLKMKAGVIYIYPDEAAANRDEPKPYPYPNLDDFLDDMNFLLALIAQGPVKTYAHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYHIDADRVVYSTKEKSLTLKELFAKLNMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWNKLSSWFVCNRIYCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFLPVFEATINPQAHPDLSVFLKHITGFDSVDDESKHSGHMFSSKSPKPEEWTMENNPSYTYYAYYMYANITVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADNISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKAKFLGNNYLEEGPVGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKATE
Protein: aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) (Q8VYI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Aspartokinase 2, chloroplastic
- Aspartokinase 3, chloroplastic
- Aspartokinase 1, chloroplastic
- Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic
- Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic
- Diaminopimelate epimerase, chloroplastic
- 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic
- 4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic
- Homoserine dehydrogenase
- Diaminopimelate decarboxylase 1, chloroplastic
Sequence:
MATFTHQTPQTHFLSRLPLRAKPRHFSARVKMSLQESAPSLAVVGVTGAVGQEFLSVLSDRDFPYSSIKMLASKRSAGKRVAFDGHEYTVEELTADSFNGVDIALFSAGGSISKEFGPLAAEKGTIVVDNSSAFRMVDGVPLVIPEVNPEAMKGIKVGMGKGALIANPNCSTIICLMAVTPLHHHAKVKRMVVSTYQAASGAGAAAMEELVQQTREVLEGKPPTCNIFGQQYAFNLFSHNAPILDNGYNEEEMKLVKETRKIWNDTEVKVTATCIRVPVMRAHAESVNLQFENPLDENTAREILKKAPGVYIIDDRASNTFPTPLDVSNKDDVAVGRIRRDVSQDGNFGLDIFVCGDQIRKGAALNAVQIAEMLL
Protein: Peroxisome biogenesis protein 7 (Peroxin-7) (AtPEX7) (Peroxisomal targeting signal type 2 receptor) (Pex7p) (Q9XF57)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal. Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol. Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:19594707}. Peroxisome matrix {ECO:0000269|PubMed:19594707}. Note=The loss of PEX12, PEX13 or PEX14 prevents the targeting of PEX7 to peroxisomes. {ECO:0000269|PubMed:19594707}.
Interaction partners:
- Peroxisome biogenesis protein 5
- Peroxisomal membrane protein PEX14
- Peroxisome biogenesis factor 10
- Peroxisome biogenesis protein 12
- 3-ketoacyl-CoA thiolase 2, peroxisomal
- Peroxisomal ATPase PEX6
- 3-ketoacyl-CoA thiolase 1, peroxisomal
- Phytanoyl-CoA dioxygenase
- 3-ketoacyl-CoA thiolase 5, peroxisomal
- Peroxisomal membrane protein 13
Sequence:
MPVFKAPFNGYSVKFSPFYESRLAVATAQNFGILGNGRIHVLELAPGAPGVTESVSYDTADAVYDVCWSESHDSVLIAAIGDGSVKIYDTALPPPSNPIRSFQEHAREVQSVDYNPTRRDSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPKHGDVFASASGDCTLRIWDVREPGSTMIIPAHDFEILSCDWNKYDDCILATSSVDKTVKVWDVRSYRVPLAVLNGHGYAVRKVKFSPHRRSLIASCSYDMSVCLWDYMVEDALVGRYDHHTEFAVGIDMSVLVEGLMASTGWDELVYVWQQGMDPRAS
Protein: Leucine-responsive regulatory protein (P96896)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MNEALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINPEAVGHLLSAFVAITPLDPSQPDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALEDLLQRIRTTANVRTRSTIILNTFYSDRQHIP
Protein: Origin recognition complex subunit 1 (Q9Z1N2)
Organism: Mus musculus (Mouse)
Function: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA replication factor Cdt1
- Origin recognition complex subunit 2
- Origin recognition complex subunit 3
- Cell division control protein 6 homolog
- Origin recognition complex subunit 5
- Origin recognition complex subunit 4
- Origin recognition complex subunit 6
- DNA replication licensing factor MCM5
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM2
Sequence:
MPSYLTRQKTRQTFSWVGRPLPNRKQFQQMYREICMKINDGSEIHIKVGQFVLIQGEDNKKPYVAKLIELFQNGAEVPPKKCARVQWFVRFLEIPVSKRHLLGRSPPAQEIFWYDCSDWDNKINVETIIGPVQVVALAPEEVIPVDQKSEETLFVKLSWNKKDFAPLPPEVLAALREQEDSPEWQKPLKAKIKNVKSPARNTTEQEVKGIKSNHSTSKFHQTPANIVIPNAKKSLELDGLGFTRKPNTRWSKKSSCDSLDYQKTSKRRAAFSETTSPPKKPNKPREIKPSSALETRVKNGQTQPFCAKSSVVLRARNPAMTTTKLGVDNTLSPIRNGLRSSVVPSGGLTPVYIRRKAKEQETHKEPIRTSRVHRKSSLLTLKRIRQQLCLLDGDDRDQEEEESVDSESEEEDEFISSLPTRNSLGQSRTRQTPSKSPQKNPKPRTPHRATPQIRDRNLAVQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATANHAAELLAKQFCGQGSQKETTVLLVDELDLLWTHKQDVMYNLFDWPTHKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRLRNLRAFEDDAIQLVARKVAALSGDARRCLDICRRATEICELSHLRGDSLSLVTVAHLMEAIDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSRLGSCRLLLVEPSRNDLLLRVRLNVSQNDVLFALKEE
Protein: Carboxynorspermidine/carboxyspermidine decarboxylase (CANS DC/CAS DC) (CANSDC/CASDC) (EC 4.1.1.96) (C-NSPD decarboxylase) (Q56575)
Organism: Vibrio alginolyticus
Function: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine. 2,3-diaminopropionic acid, 2,4-diaminobutyric acid, L-ornithine or L-lysine cannot serve as substrates.
Subcellular location: Cytoplasm {ECO:0000269|Ref.2}.
Interaction partners:
- Catalase
Sequence:
MQQNELKTPYFSINEDKLIENLEKAKQLKDISGVKLVLALKCFSTWGVFDIIKPYLDGTTSSGPFEVKLGYETFGGETHAYSVGYSEDDVRDVADICDKMIFNSQSQLAAYRHIVEGKASIGLRLNPGVSYAGQDLANPARQFSRLGVQADHIKPEIFDGIDGVMFHMNCENKDVDAFIGLLDAISAQFGEYLDKLDWVSMGGGVFFTWPGYDIEKLGLALKAFAEKHGVQMYLEPGERIITKTTDLVVTVVDIVENVKKTAIVDSATEAHRLDTLIYNEPASILEASENGEHEYVIGSCSCLAGDQFCVANFEQPLEIGQRLHILDSAGYTMVKLNWFNGLRMPSVYCERSNGDIQKLNEFDYSDFKRSLSQWSVI
Protein: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (A0A8I5ZP90)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSFFILQYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGTLCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYPSSQEDEEWLRPVMRRDKQVLVHWGFYPDSYDTWVHSNDVDAEIEDAPIPEKPWKVHVKWILDTDVFNEWMNEEDYEVDENRKPVSFRQRISTKNEEPVRSPERRERKASANARKRKHSPSPPPPTATESRKKSGKKGQASLYGKRRNQKDEDEQEDLTKDMEDPTPVPNIEEVLLPKNVNPKKDSENTPVKGGTVADLDEQDEEAVTTGGKEDEDPSKGDPSRSADAGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPIDLQNFGLRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGSEEEKMETDPDGQQPEKAENKGENESDEGDKIQDGENEKNSEKERDSDTSEDVKPEEKENEENKELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQPPQQAHQHPGGPGLAPLGAAGHPGMMPHQQPPPYPMMHHQMPPPHPPQPGQIPGPGSMMPGQPMPGRMIPTVAANIHPTGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQPPPPPADGVPPPPVPGPPASATP
Protein: Glutathione S-transferase (EC 2.5.1.18) (Q5T8R2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
Protein: Beta-toxin Ct17 (P0DUI2)
Organism: Centruroides tecomanus (Scorpion) (Centruroides limpidus tecomanus)
Function: Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity). Is possibly lethal to mice, freshwater shrimp and crickets.
Subcellular location: Secreted {ECO:0000269|PubMed:23840487}.
Interaction partners:
Sequence:
MNSLLMITACLVLIGTVWAKKDGYLVDKTGCKKTCYKLGENDFCNRECKWKHIGGSYGYCYGFGCYCEGMSDSTPTWPLPNKRCGKK