Protein: Laminin-like protein epi-1 (Laminin alphaB) (Laminin subunit alpha epi-1) (Q21313)
Organism: Caenorhabditis elegans
Function: During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12783803}. Secreted, extracellular space {ECO:0000269|PubMed:12783803}. Secreted {ECO:0000269|PubMed:12783803}. Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:12783803}.
Interaction partners:
- Dystroglycan 1
- Laminin-like protein lam-2
- Integrin beta pat-3
- Laminin subunit beta-1
- Collagen alpha-1
- Collagen alpha-2
- Integrin alpha ina-1
- Nidogen
- Spondin-1
- Fibronectin type-III domain-containing protein
Sequence:
MSPYDSSPWATKALFLIVTLLAQFTYSQVLTPSQITISHRKPITATSTCGEIQGQPVTEIYCSLTGSTQYTPLNSYSYQDDEQQKSWSQYENPMVRGGHGCGHCNAGNENSHPAANMVDGNNSWWMSPPLSRGLQHNEVNITIDLEQEFHVAYVWIQMANSPRPGSWVLERSTDHGKTYQPWFNFAENAAECMRRFGMESLSPISEDDSVTCRTDMASLQPLENAEMVIRILEHRPSSRQFATSEALQNFTRATNVRLRLLGTRTLQGHLMDMNEWRDPTVTRRYFYAIKEIMIGGRCVCNGHAVTCDILEPQRPKSLLCRCEHNTCGDMCERCCPGFVQKQWQAATAHNNFTCEACNCFGRSNECEYDAEVDLNKQSIDSQGNYEGGGVCKNCRENTEGVNCNKCSFGYFRPEGVTWNEPQPCKVCDCDPDKHTGACAEETGKCECLPRFVGEDCDQCASGYYDAPKCKPCECNVNGTIGDVCLPEDGQCPCKAGFGGTFCETCADGYTNVTAGCVECVCDATGSEHGNCSASTGQCECKPAYAGLSCDKCQVGYFGDDCKFCNCDPMGTEGGVCDQTTGQCLCKEGFAGDKCDRCDIAFYGYPNCKACACDGAGITSPECDATSGQCPCNGNFTGRTCDKCAAGFYNYPDCRGCECLLSGAKGQTCDSNGQCYCKGNFEGERCDRCKPNFYNFPICEECNCNPSGVTRDFQGCDKVSPGELCSCRKHVTGRICDQCKPTFWDLQYHHEDGCRSCDCNVNGTISGLNTCDLKTGQCMCKKNADGRRCDQCADGFYRLNSYNQMGCESCHCDIGGALRAECDITSGQCKCRPRVTGLRCDQPIENHYFPTLWHNQYEAEDAHTEDQKPVRFAVDPEQFADFSWRGYAVFSPIQDKILIDVDITKATVYRLLFRYRNPTSVPVTATVTINPRFTHTHDVEQTGKATFAPGDLPAMKEITVDGKPFVLNPGKWSLAISTKQRLFLDYVVVLPAEYYEGTVLRQRAPQPCLSHSTKNTTCVDLIYPPIPSVSRQFVDMDKVPFNYINEDGTTTALEHVPVEILLSEITGPAAFVRADENPRVVEAKLDVPETGEYVIVLEYHNREETDGNIGVGISQNDKEVLNGNAVIHHCPYATFCRELVSSEGTIPYIPLEKGEATVRLNIKPNHEFGLAGVQLIKKSDFSSEYLQQVPVCIKKDARCVQQSYPPAADSVTTEAESGSNMDKSILGDKLPFPVSNSKEMRVVPLDDAQATVEISGVVPTRGHYMFMVHYFNPDNTPINIDVLIQNEHYFQGDSCNSFACSSVPLAFCPSISGCRALIRDKERPEVIQFYMDDKYTATFYHNSSQKGPIYIDSITAVPYNSYKDKLMEPLALDLSNEFLKECSEDNLKNHPESVSDFCKQKIFSLTTDFNAAALSCDCVAQGSESFQCEQYGGQCKCKPGVIGRRCERCAPGYYNFPECIKCQCNAGQQCDERTGQCFCPPHVEGQTCDRCVSNAFGYDPLIGCQKCGCHPQGSEGGNLVCDPESGQCLCRESMGGRQCDRCLAGFYGFPHCYGCSCNRAGTTEEICDATNAQCKCKENVYGGRCEACKAGTFDLSAENPLGCVNCFCFGVTDSCRSSMYPVTIMSVDMSSFLTTDDNGMVDNKDDTVIYTSEETSPNSVYFNVPIEKKDYTTSYGLKLTFKLSTVPRGGRKSMNADADVRLTGANMTIEYWASEQPTNPEEQFTVKCKLVPENFLTAEGKTVTREELMKVLHSLQNITLKASYFDHPKTSTLYEFGLEISEPNGVDSVIKASSVEQCQCPAPYTGPSCQLCASGYHRVQSGSFLGACVPCECNGHSATCDPDTGICTDCEHNTNGDHCEFCNEGHYGNATNGSPYDCMACACPFAPTNNFAKSCDVSEEGQLLQCNCKPGYTGDRCDRCASGFFGHPQISGESCSPCQCNGNNNLTDSRSCHPNSGDCYLCEQNTDGRHCESCAAWFYGDAVTAKNCSSCECSQCGSQYCDNKSGGCECKINVEGDSCDRCKPDHWGFSKCQGCQGCHCGTAAFNTQCNVENGQCTCRPGATGMRCEHCEHGYWNYGEHGCDKCDCEADLSMGTVCDVRTGQCHCQEGATGSRCDQCLPSYLRIPTYGCRRCDECVHHLIGDVDNLELEIDVLGTAIANISSATIVGARLARNKKEFNDINEITKMLNDEENSFGNVFGDAQDILTNSTQIQNKLVRTKTHSQNSVSSAKNITLNGTEFLQEVMKRAQRARQSVRSLAEIALAIGSSSKAVNVDPRLLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRAEELAAYLNSAQQLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLERVEAAKGEFQKLNVAIGNITENLKDKREEMTHAVTTLNETRNDVAEALEAAKKRVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSAEPAFAESVQNARDKPFPDETKEKIDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQEVEKLKAEIDANIEETRAKISEIAGKAEEITEKANSAMEGIRLARRNSVQLNKLAPVIVSKFEELKKLSSARSAKVDSVSDKVSQIKEMIAVARDAANRIKLGAHFEKGSSLDLNIPQRVTRSAAHADISFYFRTEQEHGIPLFFGNEETAVGSRAVPTADYVAAEIEYGRPKITVDLGDAPAVVKLDTPVNDGLWRRLNIERIGKTVSVTLSKPNSVETAETKSSVAGGNKSVLNLNQQISRLFVGGVPTSARISKDLYNRDFVGDIESLKLHGEPIGLWNSREKGNTNVNGAQKKPKITDNADELVVSLDGEGYTSYKPSHWNPRKATKISLSFLTFSPHGLLFFVGKDKDFMALELSDGGVKLSVDLGSGVGQWITESSNYNDGKWHTVSIVREEKHVKIMIDGETEVLEGDVPGKDSEMSVTEFLYIGGTPSGLSVRTTIVPLRGCIKSVKLGSDNVDLESSHASKGVRSGCPLHSVRTVSFLSDRTTASFNNATEFSEDVSVTFKFKTRSIRQPSSLFTVNDDEDSVLSVSINEDGILTVTSGEDIATLELAASPDEKWHYVSIRKTKYIIRIDADDSFSNEVARKHADDSNPDASFLSAFFGKSGETPSFVGCIGDVTLNGKLLDFANSEIKEISLNGCSLSDDENISTTTTAAPKPTDDSDVAVLPIDEEEESTTTTTTTTTEEPTEEPAEARPDGHCSLPEDPMVQFEDAEGFNFGSQQYSRIEYDILPEAIDKSGEFTFKIRPTSDNGIIFIATNKRTDHIAVMLEHGRVVFTYDTGSGQVIIKSDKSIIDGRWHTIKVSRRGKSAHLIVDDNSYESEGAANQNEDLIETQPPFYVGGVPADLAGFARNLVVGVRSQFSGCIKDFKLNGKSLDNGKEFGTEQCSQFSEPGMYFGKDGGYAIVQKDYEVGLTFGLEVEMRPRMKNGILFSVGVLEYITVEFVNGSIKTTVESGSGGEELWHHPDIENQYCDGQWQSFKISKKRNLLTVAVNGKAHLKILKKAKTDVLTKDPLYFGGLPEGVTNKGIKTNKPFVGCIRFVSFGLKKDRKIRRKKQVDTERFDVFGDVHRNACPAI