wanglab/gogpt-training-data huggingface dataset:
Protein: Mycocyclosin synthase (EC 1.14.19.70) (Cytochrome P450 121) (Cytochrome P450 MT2) (P9WPP7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes C-C bond formation between the carbons ortho to the phenolic hydroxyl of cyclo(L-tyr-L-tyr) (cYY) producing mycocyclosin. Can also use cyclo(L-Tyr-L-Phe) (cYF), cyclo(L-Tyr-L-Trp) (cYW) and cyclo(L-Tyr-L-3,4-dihydroxyphenylalanine) (cY-DOPA) as substrate.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Cyclo
- Polyketide synthase Pks13
- Sterol 14alpha-demethylase
- Putative cytochrome P450 137
- Possible oxygenase
- Peptide synthetase MbtE
- Putative cytochrome P450 136
- Putative cytochrome P450 139
- Putative cytochrome P450 132
- Putative cytochrome P450 138
Sequence:
MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW
Protein: Dynein axonemal intermediate chain 4 (WD repeat-containing protein 78) (Q9W0U9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000256|ARBA:ARBA00004611}. Dynein axonemal particle {ECO:0000256|ARBA:ARBA00024190}.
Interaction partners:
- Male fertility factor kl3
- Uncharacterized protein
- Male fertility factor kl5
- FI19907p1
- Dynein axonemal heavy chain 7
- GH14707p
- Dynein axonemal heavy chain 2
- Dynein light chain roadblock
- Uncharacterized protein, isoform D
- Uncharacterized protein, isoform B
Sequence:
MSASVRNTVTSQENGSIFKRSSNLDNELKKKSVVVNQTQAEESKAKKKDTTHYYSVETLADLQYRSQIKVLEKIYGEEVDMTPKSIQDDTYVEQFMKYNLNVMHQMTNFTTMVAKSTTRSRTRSSVRAGIGGNKQSIDDLMNGILYETINWEPYSTVEALEEAYEPKPYTKSFLKITLRKSDFFEIHSQTQTTVAKGSPEGDDAERDNRNYEYLTIGKGKIRRRSDNDAQTDTLLFTTRAVNTILITKATVSSYVSNFEMYDTLNNITKEFATATMSSVKDLTSALAQTEDADTFEDDEAVAEKDKVSSQIERLFRSPEFRNAIMYMGRTLSSNTNEAGLRRFRNFDQVERWNAEAEYVYSMNLLFRLVPEPSKDERKAVSDIDFCRSNGDILAVAYGLYSFSSQHVPTSGSVFLWSIKNPGEPERAYYYDVPVTAINFSPFLPSLLAIGLYDGSVEVRDVSSLQDTPVAVSQRSTSPGSSPVVAIRWIKQVSDDDHETDIDPFLSLSQDGSVTRFRIIKSPFLLGFTQMILERVEGHPEGIFVHPSSRIPCESNRHPQGLSITTHPLHKDIYYVLTDEGCIHKCSINYQHQYLEVLRCHDGGVTVMEFSPWSPKLFLTCGNDWFVRIWVDGITRPLLELLDEMTPVHWAKWSPTHSTIIVTVNRETANVWDFRRNLLRPMSKHKMDSSFNTVARFSHCGRTLVIGNERGNTLFNALNDMPFSPHFQYDELEKAIFKAIGNDHELLMELKSIGFFGYPNKKAVF
Protein: Chromatin target of PRMT1 protein C-terminal domain-containing protein (Q585R3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
Sequence:
MRRDDFDRRRLRDLYDRNVRRVRALAEARDQRRSDREDDLPAPRRYLVSERRTRLEGFGYGDRQVRRSRRSRDGERSRRFSDRRLFRRSAADRFARDEDIERQLRRERRERLLRLERLERLERLERRDRLRERLPLRGGVAMGRLRRRLVEGRRRRLQRENDRQRPQQQPQRRKLDDELLQRTNRSSRGGNNSAHNKKEGARRSGPMTREGLDEQLDRFRGAA
Protein: Putative arrestin-related trafficking adapter C2D10.04 (O74798)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May regulate endocytosis in response to extracellular stimuli.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Note=Localizes at the cell tip and barrier septum.
Interaction partners:
- Uncharacterized amino-acid permease C777.04
- Putative lipase C4A8.10
- Meiotically up-regulated gene 170 protein
- Uncharacterized protein C557.05
Sequence:
MRGELNIPALSRFGKSISASLHHQNGSSRDDNDSNPYENRSSNSGLNRRNSVFGLPSSGLSSRLSKPSLSSINNSNNSSSNTGGNVLPNPALTPVRNMSNKPPLTWSPSSANLFGTSKVTSIIGNNVSDVVPPVIKKALASSHGGGMSLSIVLLEPVLYLAGFDLNECQIENPALLRGALVLRVAKPANIRGISLSFTGRSRTEWPEGIPVKGHDTYEDKVIISHNWKFYEPTMKDADAPQHGADVARLVGEQLPLPSSAAASLRGYSVFAPGEYTYNFDLAIPNCFPESVEAKMGWVRYFLEATVERFGTFKSNLNGRTPVQLVRTPSPASLSSSELINISRDWDERLHYELQVSGKSFRLGEVVPITFRFLLLDKVRLYKLSISVVESSEYWCRSRKFHRVDPKRRVLLAERSAKHQNTDNLFETPDEGDGLSSAVFNFNVALPTCLVKERDRLTFDTTYKYIKVRHRLKALLVLSIENTENPEKRKYFEINIETPVRILSCRCVKDSTLLPPYESSSQGDNQVLLPCPCRLATTHVEPTEVTAFTTQSVLASSAPSAGRPAAAQISRPAQLFRIPSTNPPPFDGDVCPPACNTPPPNYDELFDVLSSISIQDCETDRANDDTILNNRVRRSGTIREEAPHRSLSRTVSRSFEIPR
Protein: Aminopeptidase B (AP-B) (EC 3.4.11.6) (Arginine aminopeptidase) (Arginyl aminopeptidase) (Cytosol aminopeptidase IV) (O09175)
Organism: Rattus norvegicus (Rat)
Function: Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4).
Subcellular location: Secreted.
Interaction partners:
- Aspartyl aminopeptidase
- Cytosol aminopeptidase
Sequence:
MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLNGKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFNRWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGKQKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
Protein: Pyrroline-5-carboxylate reductase 2 (EC 1.5.1.2) (A0A087WTV6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTLTPSSPGKLLTRSLALGGKKD
Protein: Calcium-binding protein H (Calcium-binding protein 8) (Q966Q9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Calcium-binding protein E
- Probable serine/threonine-protein kinase roco6
- Probable serine/threonine-protein kinase roco11
- Probable serine/threonine-protein kinase qkgA
- Probable serine/threonine-protein kinase roco8
- Probable serine/threonine-protein kinase roco5
Sequence:
MSRIYEQIEKDVEKIIGQYDGDKNGEVTINEAIEFFKRMGSKYPEKCAIVLFKMYDLDNEGKISYDEIQEEIFKRYQDKVREDQIKQYFQDDIEAFLLRYDKNRDNRIDFKELEQCFESIGSDHPKENANHIFTEIDKNRDGYLTIAEIKNYCRNTIRSKPYYQS
Protein: Heterogeneous nuclear ribonucleoprotein R (V9GWW3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQVRTKVHFYVEL
Protein: DUF3105 domain-containing protein (Q9XWU5)
Organism: Caenorhabditis elegans
Interaction partners:
- Large ribosomal subunit protein mL41
- Large ribosomal subunit protein uL23m
- SRR1-like domain-containing protein
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein mL40
- Ribosomal protein
- Small ribosomal subunit protein bS6m
- Large ribosomal subunit protein mL43
Sequence:
MRLLIILSILPHITFGYMGAVMGKLTTCDDGITNLIKDWDSKDFSAFTCLNSIHYAVQKDIDSEFFDMVQQNSSYDPKKDQVMHRCMDETIDYEDRIPIRGDHRPNWARFGEYLYVPVQRWLHNLEHGSIVLLYHPCVDLDELNKLRQLVTSCIYRHVITPYIKLTAERPLALVGWGSRLEMNSVDEKKVVEFMKKYGNRAPEEITRDGLYDEYLLKEAKPVSENDKTICPNY
Protein: Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) (P13607)
Organism: Drosophila melanogaster (Fruit fly)
Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit beta-2
- Sodium/potassium-transporting ATPase subunit beta-1
- Nervana 3, isoform E
- Neurexin-4
- Multidrug resistance protein homolog 65
- Neuroglian
- Uncharacterized protein, isoform A
- Sinuous
- Na/K-ATPase beta subunit isoform 4
- HECT-type E3 ubiquitin transferase
Sequence:
MALRSDYEHGRADSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY
Protein: Plastin-2 (L-plastin) (Lymphocyte cytosolic plastin 1) (Q6P698)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Actin-binding protein. Plays a role in the activation of T-cells (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P13796}. Cell junction {ECO:0000250|UniProtKB:P13796}. Cell projection {ECO:0000250|UniProtKB:P13796}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:P13796, ECO:0000250|UniProtKB:Q61233}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q61233}; Cytoplasmic side {ECO:0000250|UniProtKB:Q61233}.
Interaction partners:
- SI:bY184L24.2.1
- Myeloid-specific peroxidase.
- Macrophage-expressed 1, tandem duplicate 1.
- GATA-binding protein 1a.
- Transcriptional activator Myb isoform 1
- Lysozyme
- Actin alpha 1, skeletal muscle b.
- Macrophage colony-stimulating factor 1 receptor
- V
- Colony-stimulating factor 3 receptor
Sequence:
MAAAQISAEEMEELREAFTKVDVDGNGHISTDELNALFKAANLPLPGYRVREIIQEISRTMDLNQDGKITFDEFAKVVHDLKSSEVAKTFRKAINKKEGICSVAGTSEQSGTQHSYSEEEKVAFVNWVNKALEKDPDCQHVLPMDPSTDDLFTAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGRQHLVLGLLWQVIKIGLFADIEISRNEALIALLRDGESLEDLVKLSPEELLLRWANYHLEEAGCPKINNFSSDIKDSKAYYNILNQVAPKRDEEGIPAIPIDISGIREKDDLKRAECMLEQADRLGCRQFVTATDVVRGNPKLNLAYVANLFNKYPALKKPENQDIDWSSIEGETREERTFRNWMNSLGVNPRVNHLYVDLADALVIFQLYEKIKVPVDWDKVNKPPYPKLGSNMKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLNILEDLGDGQKIIDETIVQWVNETLTQAGKGTISGFKDGSISSSMPVLDLIDAIQPGSIRYDLLKAEDLTDEKKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARGMRRI
Protein: ADP/ATP translocase (ADP,ATP carrier protein) (Q57UM4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU368008}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU368008}.
Interaction partners:
- Mitochondrial carrier protein, putative
Sequence:
MDHDQLYDSPQSAKDSLLDMTALLIVTFAQRAVMAPSYRVTLLATVEGELVREGRLPPKGFGGVFGCIKRLYVKEGVRSFFRGLLTDAVLSLPATVVENISSTLVSFALQVAIPVRLVESMNPWTYLTLSLSSTSAAVLLATPATGLHSTIVTNYVADIVAPVPSEKSKNPDKDDGENNKEIKEGEKGGEESYRYATATEAVASIFRRWGFSGFYRCIGADAIAVFLYRGTYYYGLQLLPSTLHNRFPYGISRCLAVVAGFLTQPFEVVSRRMQLTASSTTGRRYKGMLHCARTIVAEEGYTALWAGMQARLLVTCVGVAVLELHRHFWAV
Protein: Prostate tumor-overexpressed gene 1 protein (M0QZB9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369088}. Nucleus {ECO:0000256|RuleBase:RU369088}. Cell membrane {ECO:0000256|RuleBase:RU369088}. Cytoplasm, perinuclear region {ECO:0000256|RuleBase:RU369088}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts. {ECO:0000256|RuleBase:RU369088}.
Interaction partners:
Sequence:
EGARVFGALGPIGPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITT
Protein: Transmembrane protein 223 (A0PJW6)
Organism: Homo sapiens (Human)
Function: Mitochondrial ribosome-associated protein involved in the first steps of cytochrome c oxidase complex (complex IV) biogenesis. Stimulates the translation of MT-CO1 mRNA and is a constituent of early MT-CO1 assembly intermediates.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:34969438}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAAPWRRWPTGLLAVLRPLLTCRPLQGTTLQRDVLLFEHDRGRFFTILGLFCAGQGVFWASMAVAAVSRPPVPVQPLDAEVPNRGPFDLRSALWRYGLAVGCGAIGALVLGAGLLFSLRSVRSVVLRAGGQQVTLTTHAPFGLGAHFTVPLKQVSCMAHRGEVPAMLPLKVKGRRFYFLLDKTGHFPNTKLFDNTVGAYRSL
Protein: Uncharacterized peptidase cgR_1176 (A4QD57)
Organism: Corynebacterium glutamicum (strain R)
Subcellular location: Secreted {ECO:0000269|PubMed:19066885}.
Interaction partners:
Sequence:
MSSASFTTKALSVLAALTAASAPLVAASPAHALANARNVTGSSTTSDSIVRLHIGNTACTGTMITPTWAITARHCIPEDGIAGAAIGSSTLSQFQQVSQAILHPTADLALVELPNQASSNTVDLYGAHVQPGENGQAAGWGGYSAFGQNVAQQADVQIQRRVVNVPSPDRTAVLLEGTVSNGRLVPGDSGGPLYINGQLAGVLSMSTDVENDALDGTVGWYIPVAEHAEWIAYYTGKHIAPIAGAPAELVDATANPTFIPAPQPFTGSSIGGWALGSS
Protein: Large ribosomal subunit protein bL35m (39S ribosomal protein L35, mitochondrial) (L35mt) (MRP-L35) (Q3SZA9)
Organism: Bos taurus (Bovine)
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- Large ribosomal subunit protein bL9m
- Large ribosomal subunit protein uL13m
- Small ribosomal subunit protein uS11m
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein uL15m
- Small ribosomal subunit protein mS23
- Ribosomal_L18e/L15P domain-containing protein.
- Large ribosomal subunit protein mL65
- Large ribosomal subunit protein mL48
- Acyl carrier protein, mitochondrial
Sequence:
MAASMFAGAVRAASGILRPLNILASSAYRNCTKNACLNSILSSRHFSHIQTPVVSSAPRLITSVRNLTCGQTATVLNRMALLLPNVLKPPVRTVTYCSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTVARKRRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQMYHDRTNLKV
Protein: Cutinase cut2 (TfCut2) (EC 3.1.1.74) (Acetylxylan esterase) (BTA-hydrolase 1) (Poly(ethylene terephthalate) hydrolase) (PET hydrolase) (PETase) (EC 3.1.1.101) (Q6A0I4)
Organism: Thermobifida fusca (Thermomonospora fusca)
Function: Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Shows esterase activity towards p-nitrophenol-linked aliphatic esters (pNP-aliphatic esters). Also hydrolyzes the triglycerides triacetin, tributyrin, tricaprin, and trilaurin, with a preference for short-chain substrates. Hydrolyzes the hemicellulose xylan. Capable of degrading the plastic poly(ethylene terephthalate) (PET), the most abundant polyester plastic in the world. Can also depolymerize poly(epsilon-caprolactone) (PCL), a synthetic aliphatic biodegradable polyester. Hydrolyzes polyoxyethylenesorbate esters with a preference for shorter chain lengths.
Subcellular location: Secreted {ECO:0000269|PubMed:23604968}. Periplasm {ECO:0000269|PubMed:23604968}.
Interaction partners:
Sequence:
MAVMTPRRERSSLLSRALQVTAAAATALVTAVSLAAPAHAANPYERGPNPTDALLEASSGPFSVSEENVSRLSASGFGGGTIYYPRENNTYGAVAISPGYTGTEASIAWLGERIASHGFVVITIDTITTLDQPDSRAEQLNAALNHMINRASSTVRSRIDSSRLAVMGHSMGGGGTLRLASQRPDLKAAIPLTPWHLNKNWSSVTVPTLIIGADLDTIAPVATHAKPFYNSLPSSISKAYLELDGATHFAPNIPNKIIGKYSVAWLKRFVDNDTRYTQFLCPGPRDGLFGEVEEYRSTCPF
Protein: Nuclear receptor subfamily 1 group H member 3 (C9JJ16)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQI
Protein: AT01806p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Q8T4F2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Metaxin-1 homolog
- Glycerol-3-phosphate dehydrogenase
- FI08238p
- AT04270p
- Reticulon-like protein
- FI08446p
- GEO02361p1
- Uncharacterized protein, isoform C
- Protein clueless
- Mitochondrial import receptor subunit TOM40 homolog 2
Sequence:
MELEQNLTAALMQSSAEEGKSEEAWPADAHLHQPAEANQLLLPERSSCLAVKTFLRMCNLPFTEHISDNAEFMSPGGRLTHLPLLRLGPVKTFAEFEPIVAQVEAVQGGNCLDSWMSEDQRDNIRCLVSYVENVFTLAEIHMSFVDEVNYQLYTATRCAAAHPWPLSTIRRFAKQKDAQKILKVYRWQDLDNDQVIQEVSICADALIAELEEDQAKSYFGGSRPCKLDALVFGHVVAIMTTKLPNMELAAVLATYPRLLAHCRRIDQSLFDGKLLTSAVEEQEDEMELEKIE
Protein: Tubulin beta chain (Q8H6N0)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MREILHVQAGQCGNQIGGKFWEVVCDEHGIDATGNYVGTSPVQLERLNVYYNEASGGRYVPRAVLMDLEPGTMDSLRTGPYGKLFRPDNFVFGQNGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTNPSFGDLNHLISTTMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTIPELTQQMWDSKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNDVKSSVCDIPPTGLTMSSTFMGNSTSIQEMFRRVSEQFTVMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAVVDEDGEGYEDEAEEN
Protein: Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1) (Q92786)
Organism: Homo sapiens (Human)
Function: Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P48437}. Note=RORG promotes its nuclear localization. {ECO:0000250|UniProtKB:P48437}.
Interaction partners:
- Podoplanin
- Transcription factor SOX-18
- Vascular endothelial growth factor D
- Lymphatic vessel endothelial hyaluronic acid receptor 1
- Vascular endothelial growth factor C
- Nuclear receptor subfamily 5 group A member 2
- Forkhead box protein N4
- Vascular endothelial growth factor receptor 3
- Hepatocyte nuclear factor 4-alpha
- Hepatocyte nuclear factor 6
Sequence:
MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMCELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAMSQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTFRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSPAHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE
Protein: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) (Tartronate semialdehyde reductase) (TSAR) (P0ABQ2)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.
Interaction partners:
- 5-keto-4-deoxy-D-glucarate aldolase
- Glyoxylate carboligase
- Hydroxypyruvate isomerase
- Glycerate 2-kinase
- Galactarate dehydratase
- Glyoxylate/hydroxypyruvate reductase B
- 2-hydroxy-3-oxopropionate reductase
- Probable galactarate/D-glucarate transporter GarP
- Glycerate 3-kinase
- Glyoxylate/hydroxypyruvate reductase A
Sequence:
MKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSALACYYEKLAKVEVTR
Protein: Pre-rRNA-processing protein IPI3 (Involved in processing IST2 protein 3) (P53877)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:15528184}.
Interaction partners:
- DNA replication licensing factor MCM4
- Cell division control protein 6
- Ribosome assembly protein 4
- Origin recognition complex subunit 2
- Pre-rRNA-processing protein RIX1
- Cell division cycle protein CDT1
- Pre-rRNA-processing protein IPI1
- Probable metalloprotease ARX1
- Nucleolar GTP-binding protein 2
- Protein SDA1
Sequence:
MDEQVIFTTNTSGTIASVHSFEQINLRQCSTQSRNSCVQVGNKYLFIAQAQKALINVYNLSGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNHNLPDFNLPYLLLGSTESGKLYIWELNSGILLNVKPMAHYQSITKIKSILNGKYIITSGNDSRVIIWQTVDLVSASNDDPKPLCILHDHTLPVTDFQVSSSQGKFLSCTDTKLFTVSQDATIRCYDLSLIGSKKKQKANENDVSIGKTPVLLATFTTPYSIKSIVLDPADRACYIGTAEGCFSLNLFYKLKGNAIVNLLQSAGVNTVQKGRVFSLVQRNSLTGGENEDLDALYAMGQLVCENVLNSNVSCLEISMDGTLLLIGDTEGKVSIAEIYSKQIIRTIQTLTTSQDSVGEVTNLLTNPYRLERGNLLFEGESKGKQPSNNNGHNFMKIPNLQRVIFDGKNKGHLHDIWYQIGEPEAETDPNLALPLNDFNAYLEQVKTQESIFSHIGKVSSNVKVIDNKIDATSSLDSNAAKDEEITELKTNIEALTHAYKELRDMHEKLYEEHQQMLDKQ
Protein: Small ribosomal subunit protein eS4x (40S ribosomal protein S4-3) (Q8VYK6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein eS24y
- Small ribosomal subunit protein eS17x
- Small ribosomal subunit protein uS15z
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein uS13z/uS13y/uS13x
- Small ribosomal subunit protein eS1y
- Small ribosomal subunit protein eS26y
- Small ribosomal subunit protein uS12y
- Small ribosomal subunit protein eS24z
Sequence:
MARGLKKHLKRLNAPKHWMLDKLGGAFAPKPSSGPHKSRECLPLVLIIRNRLKYALTYREVISILMQRHIQVDGKVRTDKTYPAGFMDVVSIPKTNENFRLLYDTKGRFRLHSIKDEEAKFKLCKVRSIQFGQKGIPYLNTYDGRTIRYPDPLIKPNDTIKLDLEANKIVEFIKFDVGNVVMVTGGRNRGRVGVIKNREKHKGSFETIHIQDSTGHEFATRLGNVYTIGKGTKPWVSLPKGKGIKLTIIEEARKRLASQQAA
Protein: Non-specific lethal 1, isoform D (Non-specific lethal 1, isoform H) (Non-specific lethal 1, isoform I) (A4V2Z1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAPALTAEPLSPKEKLTSTASPSARSSSESGGVGCAVGLVKKPATPTPATATTRITRSSAAAASVTASPHLQQQRSSLAINNKRKSGNAKASNEPMGLSTAPTPHSTTSPNPSTDTAAASTSAVEHNNNDSNSTSAGNSTSADNSSTPKDNSTAQLLADLTINFEETISAEICLRKTLPDVSLGKEPVPPASVLAVATSSTSAGSALSLSAVDEVTKIEIDNIEERLSQLDGNATGRPEEHVAPPSVPVPVQEAPNTPTRPQAPPSAHLESPQPARTQQQSIQQMTPQSTTSSNNFLKDGAAGAVLEDQDIEEVLKALKTFDGGHVNPDTICEFFDEVWEEAAPAAPLPPAPPENVVDVPGAKPSCSGILVSGSNISQPNVIIKQEQRPWQESHAELEQQQHVISRRIEFLLRRMRKLQARAMCRHASEEVVGIMEWSARSSHKAPVPARSSTLTEQEATVLSIVSGRPSSTFWEEQNKHPLPASQMSNVIRHIATAAKHQQICHSASGSSATLAPSSSWYNSCNSSALPMKRPRKNQLDASVATGATPTAPAPGAVTSRQAAGTTGSATGSNTPRADDIVPGYDTYVTNELTHVSGLLHTELREVQNAIDSDATESSSGGESADEMVTYNNNQQLSLPITRRAVWRYSRDRAAIALRWSWLCSQLTDLEMKIRQHSDLYMDLTQSKGEIQLESTAKTSPSLAQPANGIKEEPGSDYLCSRARPLVLSEFRKRKLFQTTNMHTISKKAARPSNIKCGCQWPQVPCTLCTGRTDPTAPRDLVETMMPQNRVALLDAGYHPVLSFASDVSQSVHLEAVARQPDWQYRVMRSQPKAIVKAMWKAERETIASGGVGGQGGSRRSGDAAKRRYIRRKERNNNSNKEAGSGAKAAAVAAGGAGGNGSSSVGGGDSGNGTAARGKRQPQHPTGANSSSSLWPDSRQRQRQRHHSPSSTSISALSGAKKARKSATNSSSSNSTQQQQNHHGTKINNHHLNGYGDQWGEQSRSRRNSSPSNSHKNERTSERRVRPIYDINNIVIPYSMLAQSKMEIIPYKEIPIPKWRIVDSDNDKGKHSSDESMERKLSNGCVASKSEELAKQQLPPPPDQDQEQPALQPPKVNGLKENQAVKHNNNNNTNNNNNKNGLVNGNAKKDELKAAEDHDTQSKEDDDPKEKVVKPKLNGNLIKNPIDKTAETQDKIAQPAPEPPLPKRPKLETPTSNEVTKANGQLVQQQLESRESEEEPQHVDEDLSDEAFIMRHQRALLEERRRFETFLKFPWSTRSRANRRVDSRAESSGANTPDPASPAPHLGGPGHDNESIPSPLAYPLDAFNESGELLTGGQARQARRRTTSSKLKDQLERRSTTPDLRESYTVMPSPFEPLNFPLSDEVYQRLLAETYAPPRSMTVSKRAKSKSISSNCDGGNTFTGGSGSRRSSKCKIKPNGQLNGQLNGHPAAAKLNGIDAANEGGISEPEEEEMLLEDEDDDYPKHHLAPLDDEEPSTPDVEHELYDSAIDAYLADPEALEEDMGEDPFEDDDPNDPEWKTRTEGVRSRRI