wanglab/gogpt-training-data huggingface dataset:
Protein: Mce-family protein Mce1A (Q79FZ9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Conserved integral membrane protein YrbE1A
- Conserved integral membrane protein YrbE1B
- Mce-family protein Mce1B
- Mce-family protein Mce1F
- Mce-family protein Mce1C
- Mce-family protein Mce1D
- Possible Mce-family lipoprotein LprK
- Probable fatty-acid-CoA ligase FadD5
- Probable ribonucleotide transport ATP-binding protein mkl
- Probable conserved Mce associated membrane protein
Sequence:
MTTPGKLNKARVPPYKTAGLGLVLVFALVVALVYLQFRGEFTPKTQLTMLSARAGLVMDPGSKVTYNGVEIGRVDTISEVTRDGESAAKFILDVDPRYIHLIPANVNADIKATTVFGGKYVSLTTPKNPTKRRITPKDVIDVRSVTTEINTLFQTLTSIAEKVDPVKLNLTLSAAAEALTGLGDKFGESIVNANTVLDDLNSRMPQSRHDIQQLAALGDVYADAAPDLFDFLDSSVTTARTINAQQAELDSALLAAAGFGNTTADVFDRGGPYLQRGVADLVPTATLLDTYSPELFCTIRNFYDADPLAKAASGGGNGYSLRTNSEILSGIGISLLSPLALATNGAAIGIGLVAGLIAPPLAVAANLAGALPGIVGGAPNPYTYPENLPRVNARGGPGGAPGCWQPITRDLWPAPYLVMDTGASLAPYNHMEVGSPYAVEYVWGRQVGDNTINP
Protein: Eukaryotic translation initiation factor 2A (eIF-2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed] (Q8BJW6)
Organism: Mus musculus (Mouse)
Function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 2 subunit 1
- Eukaryotic translation initiation factor 2 subunit 3, X-linked
- Eukaryotic translation initiation factor 2 subunit 2
- Eukaryotic translation initiation factor 2 subunit 3, Y-linked
- RNA-binding protein 4B
- eIF-2-alpha kinase GCN2
- X-box-binding protein 1
- Translation initiation factor eIF2B subunit alpha
- Small ribosomal subunit protein eS6
Sequence:
MAPSTPLLTVRGSEGLYMVNGPPHFTESTVLPRESGRNCKVYTFSKDGTLFAWSNGEKVNIINVANKGLLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDGTAGTPNLQLYDMKTGACLKSFIQKKMQNWCPSWSDDEIICARNVNNEVHFFENNNFNTIANKLHLQKVNDFNLSPGTQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTEVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQPFLDGIFPAKTIKYQAVPSEVPSEEPKVATAYRPPALRNKPVTNSKLHEEEPPQNMKPHPGSDKPLSKTALKNQRKHEAKKAAKQEARSDAAPTPVPQSAPRNTVTQSASGDPEVDKKIKNLKKKLKAIEQLKEQAAAGKQLEKNQLEKIQKETALLQELEDLELGV
Protein: Rab3 interacting molecule, isoform S (A0A0B4K7F3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MDEMPDLSHLTPHERMQIENVLMRQKQEEEKQNEIMRRKQDEVVTLEMQIRQRSEQQKKAGVELDATCHICLKTKFADGVGHICHYCNIRCCARCGGKVTLRSNKVIWVCILCRKKQELLSKTGQWINKTAAQQDGFIRRIEPDGSSDISQHPIVDPHDTTDKRPKLERTRSAAEKENLPMQRAGSMLRRQYSQQEQPTNRRLSASDSGMDPVMSPGQQMQHHQQQQRARMQPMNPQQAQQGYGMQQQQQPRSGGAYPDDDPRYYQGELDGLMRQHPHLAHPSQVQPQHTPQSHSQQQQSQHQQQHLMPQQHRPSPQQHSQQQQQQQQHSQQFAARQQQHQQQQHQQQVQQSYHAQIHQQPQQHPHPHSQQQQHHQQMQHQHGQSVPQMGGYQKPPPLTRNLTISGGHAMDSSAYSQQQQQQQRRALAGSQYASQQQRSFSSSEEEFQHQLLAAQGAVTVTAGSDYDGGRLQVRTSLDPWRQQRSLNERDLLSSGGGGGGGVGGADFRHLSHATQRLYASADQRDRYELQLQHRERLEQYPLTRTARLDVQQRNSLNRSNHERQFSGGGAGVGPGGAGGGGAAGAYRRAPPLAAAGGGGSSSSSTTSSSYYPQSKPQIVIGPGSGYDRGSGSMASMASAAAATAADAQGQAARNSQRGGLLGATRGGGGSSSVSSTEAAYWDEPATSSSSSAAQDSRRFTERRIKKTVRFDAHDEEASILASSSLPPVTAILPSTAVDVGAATILSSGKSLDAVGVGGADWSRWEAERQGSQDSATKDSGIDTSSTFTSSEDSNRGDGPKLDLNERRSRRDMSPQGRKRVAGMVARDYRTVSGIGQSYHNQASATGYYRRGGGNGVGSAIGPGGMSLSQRSHSAAPSDGYHSSGVGGAASGGPAYGYRSTSPRRGSLSPPDDRYIDYPVLPVHGSSPNAPSVYQGPGGVSSAAASASQQQRFQSRSATATPTGSPKKRQLPQVPQTSRSAMLRDRLGQDFDERLASGGRFGRHRTRQPHHQATYRSTGMGGWERHYTGLSDSDLHSMDARMRPRHSLSPDKDFMGEFGDSDMESVVSVTSSAFSTQSERPRTSRGLSEYDKDKNGAEEAGGSKSAEGAGAEDKVDGSLSDTANDRKKGGGVDQERSPKGGSGMGKKSNSTSQLSATGRKRRMGFGKKGKNSFTVHRSEEVLPGDITRELRTGGGLGVSLGGAGGAAGGSGGAGGGGLSRGSSSEVDAIEQFFGDGAGGERFSPSLRNDGALNEFVDGLGPGQLVGRQVLGAPSLGDIQLSLCHQKGCLEVEVIRARGLQQKAQSKMLPAPYVKVYLVSGKRCVDKMKTSSARRTLDPLYQQQLVFKQSYTGCILQITVWGDYGRIEKKVFMGVAQIMLDDLNLSNIVIGWYKLFGTTSL
Protein: Cytochrome P450 3A (EC 1.14.14.-) (Q86SK3)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU368049}. Microsome membrane {ECO:0000256|RuleBase:RU368049}.
Interaction partners:
Sequence:
MDLIPNFAMETWVLVATSLVLLYIYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGA
Protein: Pericentrin-like protein, isoform O (M9PFP4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
Sequence:
MSRLKLEFEKQLNRKNKRHLTFDAARDLEQVICERDGLRELSKSFRSVLCRLAKCVAHCEEDLNATLSEEVQRLLFHSRSQDGGDDLEATISSSLNNTKHMLRVPDVHSLLEVVEDPSLVQFIDSKSNEEPSEDFDLNDCLERLKSEASYLLHLSEDLHKQRTHDESSEHLDEPEKQEHELCCEAEDGLKTTGAVNQQVLSKFLRTNSLNDQQMGVANQRKNSNPEAGKTHSSLPPDLQEHAGNASELSFQLVQLKNRLIKSEADRQNLQQQLSRTIDRNAELGQELQALRDQLSQLNSLNHTDYNEGYGLGTMKSLQEQGLDQSSASFLALQERARHLLSSSPVKEQPSRDHGNSTVILLQMIEDFCREGDKVVEFSKKDREDLQSQYAQLESQFREVNQQLCESNAKRDKFEVELKASIDKIFVLREIISELETQVQTKALNEEVLAEKAQQLEEYVSLQMRDNDILQQEVHSLKTDIGEGYQSRIRVLEEKLKQSGPTAEQGVVLSQVAEKLRDIETTLDQKTKALESLHNSNATSNSASLSVTEDVSIHGSKEPTAVGSPSHPSLTVEGVQRVTEKLDRHTRVEEAAIKRIRDLEMQVHQMRAGCVELQHERDTLQGRMEEQTQRISTLQNRLEEQRQRAEQLHRTGTSDLNTRVHELQGEVQNLYEQLAARDKQMANMRQQLQRSKEEITRLETEVEVRTQPDRSLVNKLQAEVQQKGAEIVKLKDKIRTEMINRLAIPDLMETMLADKNDEIDHLRDQLEAKEKELQASQQEASQISSPSGAAGKQEGSGGKLSARTLSDIGSITEFPEPDVERRAAMRSLTALQMSEGAGGFLHQTMETSKEAVANLTHKRTDDLSGFIVPYPVNTFEHPHYFQALGVTAQSTDGLTPGLVPRQINFSNLTEDSKLKTTSLLMHTPELPRPTTPPEIHQLRVKLSDLQTEKQRQQSELEKKLQDLQKELEQEKEKLSRQAQTLQSYEESEAKYRLRIENLESKVLETAAQAASDRENLRKELNCVSAAHEQCENAAAARKRELEKLNSEVKVKADQLHAALRRCADLELQVLTLERDLERLKNSDNSSKQYSVDEIAQQVEKELNYSAQLDSNILKAIESEEENNLDKKLQKGVQTEEETLPGTGNGTDDENFTGERELLNQLEALRAQLAVEREQCEAMSKELLGEKQHSQDIQEQDVIIIEAMRKRLETALDAEDELHKQLDQERERCERLQTQLTSLQRAESRRNSSLLLKSPGDSPRKSPRADFESELGDRLRSEIKLLVAQNERERERSADAQRSSERERQRYEKELQERVAYCERLKQEMEKLSRDKESAETELEHFNERLTLQASEIESLEARLVTLQEAETRRANTRTRQHQENVKLQAEIHELKSKLLAAEAARDCLDQKVTQLRFDVSRSGQREAKLAEALAQANDRLAHSTDDNVPAQFMQKMKEINALLAENTQENRQMAETVQFLVGERIALQKKCEELGGAGNTNVTELEERCRQLIGRYLRVESHRKALVYQKRYLKLTLEGYQASEQLALQNLRGGAEQPPQRNIKKKFKTVALAIIAIQRIKYIGRIWHTGKRIVSKSVFTITQQRSPGLNLNVAPPQSPLPGPNSNLPTNNNNLMGRLSYAPLSPPMVNFSTVQPIMLPSDFTLQAPTTSLQTTIANNNSENTLPSLARLDWPTMQKPKRAHARHH
Protein: Outer membrane porin F (P13794)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:2447060}; Multi-pass membrane protein {ECO:0000305|PubMed:25846137}.
Interaction partners:
- Porin D
- Major outer membrane lipoprotein
- PhoP/Q and low Mg2+ inducible outer membrane protein H1
- ECF sigma factor SigX
- Anaerobically-induced outer membrane porin OprE
- Conserved cytoplasmic membrane protein, CmpX protein
- Outer membrane protein OprG
- Porin B
- B-type flagellin
- Porin P
Sequence:
MKLKNTLGVVIGSLVAASAMNAFAQGQNSVEIEAFGKRYFTDSVRNMKNADLYGGSIGYFLTDDVELALSYGEYHDVRGTYETGNKKVHGNLTSLDAIYHFGTPGVGLRPYVSAGLAHQNITNINSDSQGRQQMTMANIGAGLKYYFTENFFAKASLDGQYGLEKRDNGHQGEWMAGLGVGFNFGGSKAAPAPEPVADVCSDSDNDGVCDNVDKCPDTPANVTVDANGCPAVAEVVRVQLDVKFDFDKSKVKENSYADIKNLADFMKQYPSTSTTVEGHTDSVGTDAYNQKLSERRANAVRDVLVNEYGVEGGRVNAVGYGESRPVADNATAEGRAINRRVEAEVEAEAK
Protein: TNF receptor-associated factor (EC 2.3.2.27) (E1C626)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Lipid droplet {ECO:0000256|ARBA:ARBA00004502}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- TGF-beta activated kinase 1
- Toll-like receptor 4
- Mitogen-activated protein kinase kinase kinase 7.
- Protein kinase domain-containing protein.
- Myeloid differentiation primary response protein MyD88
- PPM-type phosphatase domain-containing protein.
- Toll-like receptor 3
- TNF receptor-associated factor
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Protein kinase domain-containing protein.
Sequence:
MSLLHSDSSCGGRDLDSGCCTAMASACSGGAKEDSVSVGSGTGNPPSSFTEETQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKGCIVKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLTVKCPNKGCCLKMELRHLEEHQLHCDFTTVECPQCQGAFQKNHLKEHMTQECPRRQVCCPNCATSMAYEDKELHDQTCPLANVFCEYCNTMLIRQQMPNHYDNDCPTAPVPCFYSAFGCPEKMQRNELARHMQEFTQVHMRMMAQSIQNISVTATNPVPFINGLPFEPALFSHVSRAPYNCNPEVENFKETIQQLEGRLVRQDHQIRELIAKMETQNTHMAELKRTIRDLEGKITEMEAQQCNGIYIWKIENFSGLQKAQEEERPVVMHSPGFYTGKPGYKLCLRLHIQLPSAQRCANFISLFVHTMQGEYDSHLPWPFQGTIRLSILDQSEGPERQNHEEVMEAKPELLAFQRPTIHRNPKGFGYVTFMHLQTLKQRTFVKDDTLLVRCEVLTRLDLNSLRREGFQARSTDGAA
Protein: Poliovirus receptor (Tage4 receptor) (Q8K094)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- T-cell immunoreceptor with Ig and ITIM domains
- CD226 antigen
- T-cell surface protein tactile
- Nectin-3
- Cytotoxic T-lymphocyte protein 4
- Killer cell lectin-like receptor subfamily C, member 1
- Programmed cell death protein 1
- NKG2-D type II integral membrane protein
- Hepatitis A virus cellular receptor 2 homolog
- Dynein light chain Tctex-type 1
Sequence:
MAQLARATRSPLSWLLLLFCYALRKAGGDIRVLVPYNSTGVLGGSTTLHCSLTSNENVTITQITWMKKDSGGSHALVAVFHPKKGPNIKEPERVKFLAAQQDLRNASLAISNLSVEDEGIYECQIATFPRGSRSTNAWLKVQARPKNTAEALEPSPTLILQDVAKCISANGHPPGRISWPSNVNGSHREMKEPGSQPGTTTVTSYLSMVPSRQADGKNITCTVEHESLQELDQLLVTLSQPYPPENVSISGYDGNWYVGLTNLTLTCEAHSKPAPDMAGYNWSTNTGDFPNSVKRQGNMLLISTVEDGLNNTVIVCEVTNALGSGQGQVHIIVKEKPENMQQNTRLHLGYIFLIVFVLAVVIIIAALYTIRRCRHGRALQSNPSERENVQYSSVNGDCRLNMEPNSTR
Protein: SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (P63280)
Organism: Mus musculus (Mouse)
Function: Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Essential for nuclear architecture, chromosome segregation and embryonic viability. Necessary for sumoylation of FOXL2 and KAT5 (By similarity). Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:18681895, ECO:0000269|PubMed:8610150, ECO:0000269|PubMed:9223278}. Cytoplasm {ECO:0000269|PubMed:18681895, ECO:0000269|PubMed:9223278}. Note=Mainly nuclear (PubMed:18681895). In spermatocytes, localizes in synaptonemal complexes (By similarity). Recruited by BCL11A into the nuclear body (PubMed:18681895). {ECO:0000250|UniProtKB:P63279, ECO:0000269|PubMed:18681895}.
Interaction partners:
- Ran GTPase-activating protein 1
- E3 SUMO-protein ligase RanBP2
- Small ubiquitin-related modifier 1
- SUMO-activating enzyme subunit 2
- Small ubiquitin-related modifier 2
- Small ubiquitin-related modifier 3
- SUMO-activating enzyme subunit 1
- E3 SUMO-protein ligase PIAS1
- E3 SUMO-protein ligase NSE2
- RNA-binding protein with serine-rich domain 1
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
Protein: DI01187p (A1Z893)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRLGQTVPNFEADTTKGPIKFHEWQGNSWVVLFSHPADFTPVCTTELGRIAVHQPEFAKRNTKCLAHSVDALNSHVDWVNDIKSYCLDIPGDFPYPIIADPTRDLAVTLGMLDEEQKKDPEVGKTIRALFIISPDHKVRLSMFYPMSTGRNVDEILRTIDSLQLTDRLKVVATPANWTPGTKVMILPSVTDDEAHKLFPKGFDKVSMPSGVNYVRTTENY
Protein: Probable beta-1,4-xylosyltransferase IRX14 (EC 2.4.2.-) (OsGT43J) (Probable glucuronosyltransferase Os06g0687900) (Protein IRREGULAR XYLEM 14 homolog) (OsIRX14) (Q653F4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable beta-1,4-xylosyltransferase involved in xylan biosynthesis in cell walls.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:24525904}; Single-pass type II membrane protein {ECO:0000305|PubMed:24525904}.
Interaction partners:
Sequence:
MMKSLLPQSQLRRSAAAASAARSSGGGAGSGGADGAGSDGGAGGRAPATSTFWFLLHALCCLVSLFLGFRFSRLLFFLLFSTTALYSSTSSSSSSAVLRATTTTTTTTTTTTTTTNTFTLSFQANPNPPPSNLSNHTALDAAGAAGHTQSHVVVGRHGIRIRPWPHPDPVEVMRAHRIMERVQEEQRRWYGVKEPRHVLVVTPTYSRAFQALHLTGLLHSLRNVPYPLTWIVVEAGGTTNATASLLARSDLTIVHIPFPDRMPHDWADRHATENRMRLHALRVIRERKMDGVIVFADDSNVHSLELFDEVQKVQWMGAVSVGILAHTGTADQPRLSEEDKQNMPLPVQGPACNSSGHLAGWHTFNSLPFAGKTATVVGEAAPVLPRGLEWAGFVLNSRILWKEAEGKPDWVKDLDAVGENGEEIENPLILLNDPSSVEPLGNCGKKILLWWLRVEARADSKFPQGWVIEPPLDIVVPAKRTPWPETTAELSAELVDSKQDQEGRRLSRTDRSSRSRSTTKRKEN
Protein: Transcription repressor MYB4 (Myb-related protein 4) (AtMYB4) (Q9SZP1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription repressor involved in regulation of protection against UV. Mediates transcriptional repression of CYP73A5, the gene encoding trans-cinnamate 4-monooxygenase, thereby regulating the accumulation of the UV-protectant compound sinapoylmalate.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Trans-cinnamate 4-monooxygenase
- Transcription factor GLABRA 3
- Transcription factor EGL1
- Protein TRANSPARENT TESTA GLABRA 1
- Transcription factor TT8
- Dihydroflavonol 4-reductase
- Anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase
- Naringenin,2-oxoglutarate 3-dioxygenase
- Flavonol synthase/flavanone 3-hydroxylase
- Flavonoid 3'-monooxygenase
Sequence:
MGRSPCCEKAHTNKGAWTKEEDERLVAYIKAHGEGCWRSLPKAAGLLRCGKSCRLRWINYLRPDLKRGNFTEEEDELIIKLHSLLGNKWSLIAGRLPGRTDNEIKNYWNTHIRRKLINRGIDPTSHRPIQESSASQDSKPTQLEPVTSNTINISFTSAPKVETFHESISFPGKSEKISMLTFKEEKDECPVQEKFPDLNLELRISLPDDVDRLQGHGKSTTPRCFKCSLGMINGMECRCGRMRCDVVGGSSKGSDMSNGFDFLGLAKKETTSLLGFRSLEMK
Protein: V-type ATP synthase alpha chain (EC 7.1.2.2) (V-ATPase subunit A) (Q56403)
Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.
Interaction partners:
Sequence:
MIQGVIQKIAGPAVIAKGMLGARMYDICKVGEEGLVGEIIRLDGDTAFVQVYEDTSGLKVGEPVVSTGLPLAVELGPGMLNGIYDGIQRPLERIREKTGIYITRGVVVHALDREKKWAWTPMVKPGDEVRGGMVLGTVPEFGFTHKILVPPDVRGRVKEVKPAGEYTVEEPVVVLEDGTELKMYHTWPVRRARPVQRKLDPNTPFLTGMRILDVLFPVAMGGTAAIPGPFGSGKTVTQQSLAKWSNADVVVYVGCGERGNEMTDVLVEFPELTDPKTGGPLMHRTVLIANTSNMPVAAREASIYVGVTIAEYFRDQGFSVALMADSTSRWAEALREISSRLEEMPAEEGYPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRLDASLAFRRHFPAINWNGSYSLFTSALDPWYRENVAEDYPELRDAISELLQREAGLQEIVQLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIMKMILAFYKEAEAAIKRGVSIDEILQLPVLERIGRARYVSEEEFPAYFEEAMKEIQGAFKALA
Protein: WW domain-containing oxidoreductase (A0A411HBC7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. Lysosome {ECO:0000256|ARBA:ARBA00004371}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWALSERLIQERLGSQSG
Protein: Ferric uptake regulation protein (Ferric uptake regulator) (Q03456)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon. Involved in exotoxin A regulation, siderophore regulation and manganese susceptibility.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Probable ATP-binding component of ABC transporter
- Probable ATP-binding component of ABC transporter
- Thioredoxin
- Outer membrane protein assembly factor BamE
- Probable ATP-binding component of ABC transporter
- Thioredoxin peroxidase
- RNA-binding protein Hfq
Sequence:
MVENSELRKAGLKVTLPRVKILQMLDSAEQRHMSAEDVYKALMEAGEDVGLATVYRVLTQFEAAGLVVRHNFDGGHAVFELADSGHHDHMVCVDTGEVIEFMDAEIEKRQKEIVRERGFELVDHNLVLYVRKKK
Protein: RE21729p (Q5U176)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFKDGRELKTDTGSHRIMLPAGGLFFLKVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPGVLWRRTASGGNMPLRRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQFELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITVGTRYFNSGLDLSEARASLLSGDVVELSNASVVDSTSMKLTWQIINGKYVEGFYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTSASASASASALISTKPNIAAAGKRDGETNQSGGGAPTPLNTKYRMLTILNGGGASSCTITGLVQYTLYEFFIVPFYKSVEGKPSNSRIARTLEDVPSEAPYGMEALLLNSSAVFLKWKAPELKDRHGVLLNYHVIVRGIDTAHNFSRILTNVTIDAASPTLVLANLTEGVMYTVGVAAGNNAGVGPYCVPATLRLDPITKRLDPFINQRYPINQDHVNDVLTQPWFIILLGAILAVLMLSFGAMVFVKRKHMMMKQSALNTMRGNHTSDVLKMPSLSARNGNGYWLDSSTGGMVWRPSPGGDSLEMQKDHIADYAPVCGAPGSPAGGGTSSGGSGGAGSGASGGDDIHGGHGSERNQQRYVGEYSNIPTDYAEVSSFGKAPSEYGRHGNASPAPYATSSILSPHQQQQQQQPRYQQRPVPGYGLQRPMHPHYQQQQHQQQQAQQTHQQHQALQQHQQLPPSNIYQQMSTTSEIYPTNTGPSRSVYSEQYYYPKDKQRHIHITENKLSNCHTYEAAPGAKQSSPISSQFASVRRQQLPPNCSIGRESARFKVLNTDQGKNQQNLLDLDGSSMCYNGLADSGCGGSPSPMAMLMSHEDEHALYHTADGDLDDMERLYVKVDEQQPPQQQQQLIPLVPQHPAEGHLQSWRNQSTRSSRKNGQECIKEPSELIYAPGSVASERSLLSNSGSGTSSQPAGHNV
Protein: N-geranyl-L-glutamate oxidase (EC 1.14.14.-) (Domoic acid biosynthesis cluster protein D) (PmDabD) (A0A386KZI3)
Organism: Pseudo-nitzschia multiseries (Marine planktonic diatom) (Nitzschia pungens f. multiseries)
Function: Cytochrome P450 monooxygenase: part of the gene cluster that mediates the biosynthesis of domoic acid (DA) and derivatives, natural products with neurochemical activity acting as ionotropic glutamate receptor (iGluR) agonists, thus being neurotoxins causing amnesic shellfish poisoning (ASP). Catalyzes the conversion of N-geranyl-L-glutamic acid (L-NGG) to N-(7'-carboxy-7'-demethylgeranyl)-L-glutamic acid (cNGG) via three successive steps involving N-(8'-hydroxygeranyl)-L-glutamic acid and N-(8'-oxogeranyl)-L-glutamic acid as intermediates.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MNIATASLCAGLAVSGKFLSKYYQFLSTSQSDEVGFIEIMNMGMTGNDAVACASLGFVMYCVLSFARSYYRFRFSPLRNAPGFGPKSFVYGMFYEFLEAPFMEPPIEALKKLRKGGNDIPFLAYTTLFGSQRLLLLDCDLIKQVFTAPSGRDPMRYPKHYVYLREVVGDGLVVVEGSEWSRHRRIVQPAFQSAFLRDAITTTVPTLVENLVDVWKKTAGTSINLNAHLSIITLDVIGKVAFSHEFNASKLLNEWAECPDKELGEVDDPLISSIGAAFSSSPLKLMLTVLKQPWLEKHLSPAFRTSRNLLNKAADDIVQNAKNIDDPKRRSVLNLMMEAKDDESSKARNKLTDTELRDEVKTFLVAGHETTSTWAHWSLYVLATRPDIQEKVFADITKHSPDDKTILLEQADQMEYLWAFMNETLRLYSPLGLISRVTHKEENFKGYTIPAGTNLRIPIHLIHRHPDHWKDPEDFKPERWFDTEESSKRHKFAFIPFAAGGRNCIGQRFASMEAKIIVANVAKNFEIHLADSMKGKKITFSNFISLKCKPEIEIYVTPRG
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (B7Z0W0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cdc42 homolog
- Rho-type guanine nucleotide exchange factor, isoform F
- Ras-related protein Rac1
- Dreadlocks, isoform B
- AT17867p
- non-specific serine/threonine protein kinase
- Ras-related protein Rac2
- LIM domain kinase 1
- Moesin/ezrin/radixin homolog 2
- ARF GTPase-activating protein Git
Sequence:
MSSEEDKPPAPPVRLTSNRGGNERSGGGVGVGGGGLGGGGMGDVPPDMRPLPKEPDDSDRKKKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQEQKKNPQAVLDVLKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMPVAPATTPATPLQNHRTPGGISAPAASPMMHNNATTTLDKNKNNATPTSPTTTKTTAETEGTDATSTLLSATNPSCSTTPTTDPAPAAPRGSLVETATAHATTAAATVATSTTTNHHSSASSFSSFPSFHDDDGTHHALPTIHCPTPTSSSRNSTVSFPVAVPLPPIVTPASPTPASIESPDLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEATKGN
Protein: S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase 10) (Esterase D) (Sid 478) (Q9R0P3)
Organism: Mus musculus (Mouse)
Function: Serine hydrolase involved in the detoxification of formaldehyde.
Subcellular location: Cytoplasm. Cytoplasmic vesicle {ECO:0000250}.
Interaction partners:
- Alcohol dehydrogenase class-3
- Alcohol dehydrogenase 1
- All-trans-retinol dehydrogenase [NAD
- Alcohol dehydrogenase 6A
- All-trans-retinol dehydrogenase [NAD
- Alcohol dehydrogenase 6B
Sequence:
MALKQISSNRCFGGLQKVFEHSSVELKCKMRFAVYLPPQAESGKCPALYWLSGLTCTEQNFISKSGYQQAASEHGLVVIAPDTSPRGCNIKGEDDSWDFGTGAGFYVNATEDPWKANYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYRSVSAFAPICNPVLCSWGKKAFSGYLGPDESKWKAYDATCLVKAYSGSQIDILIDQGKDDEFLSNGQLLPDNFIAACTEKKIPVVFRLQEGYDHSYYFIATFIADHIRHHAKYLNA
Protein: Terpentetriene synthase (EC 4.2.3.36) (Q9AJE3)
Organism: Kitasatospora griseola (Streptomyces griseolosporeus)
Function: Involved in the production of the isoprenoid antibiotic terpentecin. Converts terpentedienol diphosphate (TDP) into terpentetriene (TTE). Can also accept geranylgeranyl diphosphate (GGDP) and farnesyl diphosphate (FDP) as substrates.
Interaction partners:
- Terpentedienyl-diphosphate synthase
Sequence:
MPDAIEFEHEGRRNPNSAEAESAYSSIIAALDLQESDYAVISGHSRIVGAAALVYPDADAETLLAASLWTACLIVNDDRWDYVQEDGGRLAPGEWFDGVTEVVDTWRTAGPRLPDPFFELVRTTMSRLDAALGAEAADEIGHEIKRAITAMKWEGVWNEYTKKTSLATYLSFRRGYCTMDVQVVLDKWINGGRSFAALRDDPVRRAIDDVVVRFGCLSNDYYSWGREKKAVDKSNAVRILMDHAGYDESTALAHVRDDCVQAITDLDCIEESIKRSGHLGSHAQELLDYLACHRPLIYAAATWPTETNRYR
Protein: Retinol-binding protein 2 (A0A8A1UF31)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
HCAGGHVSGIPYVISYLHXXXXXXXXXXXXXXXXXXXXEIWTLPKVLGERYSADKDVVVLTSGHTGGVAEDIAYILKQMRRAIVVGERTEGGAXXXQKLRIGQSDFFLTVPVSRSLGP
Protein: Putative pentatricopeptide repeat-containing protein At1g53330 (Q9MAG8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved during embryo development.
Interaction partners:
Sequence:
MSAVKSVSSFRLASLLRRENDPSAAMKLFRNPDPESTNPKRPFRYSLLCYDIIITKLGGSKMFDELDQVLLHLKTDTRIVPTEIIFCNVINFFGRGKLPSRALHMFDEMPQYRCQRTVKSLNSLLSALLKCGELEKMKERLSSIDEFGKPDACTYNILIHGCSQSGCFDDALKLFDEMVKKKVKPTGVTFGTLIHGLCKDSRVKEALKMKHDMLKVYGVRPTVHIYASLIKALCQIGELSFAFKLKDEAYEGKIKVDAAIYSTLISSLIKAGRSNEVSMILEEMSEKGCKPDTVTYNVLINGFCVENDSESANRVLDEMVEKGLKPDVISYNMILGVFFRIKKWEEATYLFEDMPRRGCSPDTLSYRIVFDGLCEGLQFEEAAVILDEMLFKGYKPRRDRLEGFLQKLCESGKLEILSKVISSLHRGIAGDADVWSVMIPTMCKEPVISDSIDLLLNTVKEDGPLSAMPQC
Protein: Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Peptidase inhibitor 9) (PI-9) (P50453)
Organism: Homo sapiens (Human)
Function: Granzyme B inhibitor.
Subcellular location: Cytoplasm.
Interaction partners:
- Granzyme B
- Cathepsin G
- Caspase-1
Sequence:
METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP