wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger RANBP2-type containing 3 (Zinc finger, RAN-binding domain containing 3, isoform CRA_g) (F5GYN7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MWGMLNRKAQVTGSTLNGRKEKIQAEEGDKEKWDFLQFAEAWTPNDSSEELRKEALFTHFEKEKQHDIRSFFVPQPKKRQLMTSCDESKRFREENTVVSSDPTKTAARDIIDYESDVEPETKRLKLAASEDHCSPSEETPSQSKQIRTPLVESVQEAKAQLTTPAFPVEGWQCSLCTYINNSELPYCEMCETPQGSAVMQIDSLNHIQDKNEKDDSQKDTSKKVQTISDCEKQALAQSEPGQLADSKEETPKIEKEDGLTSQPGNEQWKSSDTLPVYDTLMFCASRNTDRIHIYTKDGKQMSCNFIPLDIKLDLWEDLPASFQLKQYRSLILRFVREWSSLTAMKQRIIRKSGQLFCSPILALEEITKQQTKQNCTKRYITKEDVAVASMDKVKNVGGHVRLITKESRPRDPFTKKLLEDGACVPFLNPYTVQADLTVKPSTSKGYLQAVDNEGNPLCLRCQQPTCQTKQACKANSWDSRFCSLKCQEEFWIRSNNSYLRAKVFETEHGVCQLCNVNAQELFLRLRDAPKSQRKNLLYATWTSKLPLEQLNEMIRNPGEGHFWQVDHIKPVYGGGGQCSLDNLQTLCTVCHKERTARQAKERSQVRRQSLASKHGSDITRFLVKK
Protein: Serine/threonine-protein kinase SKS1 (EC 2.7.11.1) (Suppressor kinase of SNF3) (Q12505)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May have a role in glucose regulation.
Interaction partners:
- Protein GIS4
- Activator of stress genes 1
- DNA repair protein RAD51
- M-phase inducer phosphatase
Sequence:
MLSDCLLNNFRITAQIGSGAYGLVFHVVDILTSREYAVKTVFKSSSMDEFYNKNGLNNNSQVARTTLLQTQLYHFFKSFQKKLFLPSVDLDSILQLTENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLSTKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPWLKAHQKEDNTFQHFANDNNVLKKILPISDELFTVLTKILQLNPYTRIDMKTLMSEVSSLTSFTREGPLSQVPILSSEVYMTHIIRNENLFLSDLSHFSADQEQQQQQQQQQQQVQEQEQEQKQEQIQNQEQAQQQQEEEDAEPESDIPSTYNSDGSMEKYEYTNNHNNSTFLTSSMDSTPYQSDIDDVSASKDCKFQQDTLRNRLLCLQMNFSTLTDGPNEKWLPDY
Protein: R-linalool synthase QH5, chloroplastic (EC 4.2.3.26) (Q9SPN1)
Organism: Artemisia annua (Sweet wormwood)
Function: Monoterpene synthase that catalyzes the formation of (3R)-linalool from geranyl diphosphate, but not from isopentenyl diphosphate, dimethylallyl diphosphate, chrysanthemyl diphosphate, farnesyl diphosphate, (+)-copalyl diphosphate or geranylgeranyl diphosphate.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MASISLFPYSILKQTSPLARGTAYNRIYSTKTTGITVDVAESHVRRSANYEPSSWSFDHIQSLSSKYTGDDCVARANTLKESVKTMIRKEGNLLRTLELVDELQRLGISYLFEGEISNLLETIYYNHYKFPEKWNKFDLNLKALGFRLLRQHGYHVPQEIFLNFKDKNQNLNSYLLEDVVGMLNLYEASYHSFEDESILTEARDIATKYLKASLEKIDGSILSLVSHALDNRLHWRVPRVESKWFIEVYEKRVGASPTLIELAKLDFDMVQAIHLEDLKHASRWWRNTSWDTKLTFARDMLVENFLWTVGFSYLPNFSHGRRTITKVAAMITTLDDVYDVFGTLGELEQFTDVINRWDIKAIEQLPDYMKICFFGLYNSINDITYETLATKGFLILPYIKKAWADLCKSYLVEAQWYHRGHIPTLNEYLDNACVSISGPVALMHVHFLTSVSSTKEIHHCIERTQNIVRYVSLIFRLTDDLGTSLGEMERGDTLKSIQLYMHETGATEPEARSYIKSLIDKTWKKLNKERAIVSSESSREFIDYATNLARMAHFMYGEGDEDFRLDVIKSHVSSLLFTPIQGI
Protein: Pickpocket 25 (A1Z6S4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Chemosensory protein B 42a
- Gustatory and pheromone receptor 32a
- Pickpocket 17, isoform A
- Pickpocket 6
- Sodium channel protein Nach
- Uncharacterized protein, isoform B
Sequence:
MESKMSRPKQPDWLAELCQESSIHGMPYIARRDLHWAERLFWTFIILGSAYYAISSCLNQWYRFRDNPIVYEYEYLFGLRIFPFVGITLCPRYHDETEIPRLINQTWGVDPSEDKEKAVYYRKFLLAINGLRYSTLETLEPFENDTTLDNVNYLNILLTLQKKVIAVKIPPELAPIITEVGLCQTSSQLNRYGNPYGKLETQDMEPMKQCGYLSNCITSLKPINSIVAPIFMYLHDVEEMMLPDDMRTPSFDAKDIESKDLDIMLHTTSAESEVRNLPVAYRKCRFSDENNLQYYSPYHPSLCRLECRIKWALSLCNCKPYFYVAAPEVPICTVSGMLCLARSKWLERPCDCYPSCREETFTIFKVSDQTGGDDNYSGERFERTLIINLQISRMGINRRVVFSTDQLIMSFGGAIGLFLGASFMTIYGVVYFFLTFIAYTCKNRFCKRFFF
Protein: Heat shock factor protein 2 (HSF 2) (HSF 3B) (HSTF 3B) (Heat shock transcription factor 2) (HSTF 2) (P38530)
Organism: Gallus gallus (Chicken)
Function: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. HSF2 shows constitutive DNA binding activity, even without heat shock.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation. {ECO:0000250}.
Interaction partners:
- Family with sequence similarity 204 member A.
- Transmembrane protein 184C
- F-box/LRR-repeat protein 8
- AlkB homolog 4, lysine demethylase.
- HSF_DOMAIN domain-containing protein.
- Prominin 2
Sequence:
MKQEPQQQQPAQQPPPAGAGVPAFLSKLWALVGEAPSNQLITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHVDSGIVKLERDGLVEFQHPYFKQGREDLLEHIKRKVSSSRPEENKISQEDLSKIISSAQKVEIKQETIESRLSALKRENESLWREVAELRAKHLKQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGPTKSNVFQQIVKEPADNNNHVPLNRTEGLKQREQISDDIIIYDVTEDVADEENTMVDEENAPITPETNEDTTSDSSNCSRSPDIVIVEDDNEEEYAPVIQGDKSTESVAVSANDPLSPVSDSTSPLMSSAVQLNNQSTLTAEDPVSMMDSILNENGVISQNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLFDLFTSSVQMNPTDHIPNTKMETKGIETTKSNAGPAASQETQVSKPKSDKQLIQYTAFPLLAFLDGNPGSTVESGSSATETPSSVDKPLEVDELLESSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPMDTDMPFLDN
Protein: AUGMIN subunit 4 (Q8GYM3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in microtubules reorganization during spindle and phragmoplast development.
Subcellular location: Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:22505726}. Cytoplasm, cytoskeleton, phragmoplast {ECO:0000269|PubMed:22505726}. Note=Preferentially localizes to microtubules minus ends. {ECO:0000269|PubMed:22505726}.
Interaction partners:
- AUGMIN subunit 7
- AUGMIN subunit 3
- AUGMIN subunit 1
- AUGMIN subunit 6
- AUGMIN subunit 5
- AUGMIN subunit 2
- AUGMIN subunit 8
Sequence:
MVKALQGAAQNLPADVNQLIDQLERHCLAPDGSLVTKSVYSDLQLAREEMSRERLRYLEAMAIYCEAVAMVEEYQQAISVANHGGIRDVQGLYPQLGLKNSPQVYETLEHRLVVAEAAQKLRLPLISDGGEIHEEEIEKWSILSRSSLDSASTSFTISSTSNSVNYANSSANSVAGGISLSAVDTDVVGGVPNRFLGITPAYLSYVQLQNTISMDMADYQMFLAREIEGRLKEKCDKLADAIVDDTDSSTGNRNSSARLPERVKFIIEEIERDEAALREDLYSADRKFAEYYNVLEQILGVLIKLVKDLKLEHQHKYNEMQKTWLCKRCETMNAKLRVLENVLLLETYTPDSISALHNIRNYLVEATEEASAAYNKAVTRLREYQGVDPHFDTIARQYHDIVKKLENMQWTIHQVEMDLKSHD
Protein: Crotamine-IV-2 (P86193)
Organism: Crotalus durissus cumanensis (South American rattlesnake)
Function: Cationic peptide that possesses multiple functions. It acts as a cell-penetrating peptide (CPP), and as a potent voltage-gated potassium channel (Kv) inhibitor. It exhibits antimicrobial activities, and hind limb paralysis (By similarity). It also induces potent blockade of neuromuscular transmission in young chicken biventer cervicis preparation and potent myotoxic effect. In mice, it induces myonecrosis, upon intramuscular or subcutaneous injections.
Subcellular location: Secreted {ECO:0000269|PubMed:17828447}.
Interaction partners:
Sequence:
YKRCHIKGGHCFPKEKLICIPPSSDIGKMDCPWKRKCCKKRS
Protein: TRAF-like family protein (F4JZS4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- WD repeat-containing protein GTS1
- Short integuments 2, mitochondrial
- Ubiquitin carboxyl-terminal hydrolase 14
- Ubiquitin carboxyl-terminal hydrolase 15
- Small ribosomal subunit protein cS23z
- Small ribosomal subunit protein cS23y
Sequence:
MDTQKWSIGFISLAFLFITSSSAELLIKQRNRIQQFSQFTNGVTRVWRDDRPSDKILSITSFSIIRTRPEPYESSVFEAVGYKWRLVLYVNGNEKDGGKDHVSLYAKIVETESLPVGWEVNVDLKLFVYNGKLNKYLIVTDGTVKRYNNATKELGYGQLIPQSTFYDGNDGYREQDTGTFGAEIYIVKPAQQKEKVTFISNPPDNVFTWKILHFSTLEDKVYQSNEFLVGDRYWKLGLNPKGGLVPIFLYAQGFKANAVVTTTYAATNLRLKNQRSSNHVTTYTAYWYLIPSGLGLGVNTIPLSDVKDASKGYVVNDSIIIEVEMLTVSVTNIVSA
Protein: B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1) (Q9C0K0)
Organism: Homo sapiens (Human)
Function: Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus. Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes. Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). May also function in the P53-signaling pathway (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- COUP transcription factor 1
- BCL11 transcription factor A
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- AT-rich interactive domain-containing protein 1B
- B-cell CLL/lymphoma 7 protein family member A
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
- Bromodomain-containing protein 9
- Histone-lysine N-methyltransferase SUV39H1
- Histone deacetylase 1
- Actin-like protein 6A
Sequence:
MSRRKQGNPQHLSQRELITPEADHVEAAILEEDEGLEIEEPSGLGLMVGGPDPDLLTCGQCQMNFPLGDILVFIEHKRKQCGGSLGACYDKALDKDSPPPSSRSELRKVSEPVEIGIQVTPDEDDHLLSPTKGICPKQENIAGPCRPAQLPAVAPIAASSHPHSSVITSPLRALGALPPCLPLPCCSARPVSGDGTQGEGQTEAPFGCQCQLSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEPGPASSSLTPRLTIPPPLGPEAVAQSPLMNFLGDSNPFNLLRMTGPILRDHPGFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMRLNPMAIDSPAMDFSRRLRELAGNSSTPPPVSPGRGNPMHRLLNPFQPSPKSPFLSTPPLPPMPPGGTPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELAGEGLKAADGDFRHHESDPSLGHEPEEEDEEEEEEEEELLLENESRPESSFSMDSELSRNRENGGGGVPGVPGAGGGAAKALADEKALVLGKVMENVGLGALPQYGELLADKQKRGAFLKRAAGGGDAGDDDDAGGCGDAGAGGAVNGRGGGFAPGTEPFPGLFPRKPAPLPSPGLNSAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSSENGSLRFSTPPGDLLDGGLSGRSGTASGGSTPHLGGPGPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS
Protein: Complex I intermediate-associated protein 30, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1) (Q9Y375)
Organism: Homo sapiens (Human)
Function: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16218961, ECO:0000269|PubMed:17557076}. Mitochondrion matrix {ECO:0000305|PubMed:17557076}. Note=Peripherally associated with the matrix face of the mitochondrial inner membrane. {ECO:0000305|PubMed:17557076}.
Interaction partners:
- Complex I assembly factor TMEM126B, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- Complex I assembly factor ACAD9, mitochondrial
- Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex assembly factor 3
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase iron-sulfur protein 5
Sequence:
MALVHKLLRGTYFLRKFSKPTSALYPFLGIRFAEYSSSLQKPVASPGKASSQRKTEGDLQGDHQKEVALDITSSEEKPDVSFDKAIRDEAIYHFRLLKDEIVDHWRGPEGHPLHEVLLEQAKVVWQFRGKEDLDKWTVTSDKTIGGRSEVFLKMGKNNQSALLYGTLSSEAPQDGESTRSGYCAMISRIPRGAFERKMSYDWSQFNTLYLRVRGDGRPWMVNIKEDTDFFQRTNQMYSYFMFTRGGPYWQEVKIPFSKFFFSNRGRIRDVQHELPLDKISSIGFTLADKVDGPFFLEIDFIGVFTDPAHTEEFAYENSPELNPRLFK
Protein: Paired box protein (O16804)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
HGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSIYTPAIGPSIGCSSVVPGSDYAYNPAYTQYGGAYGSYGYGTGSGLINSSYYYESGQTQSPLTHDLRSPLVATRANSLASAASPGSGSACTKSESSDIFLA
Protein: Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Q6P791)
Organism: Rattus norvegicus (Rat)
Function: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation (By similarity). Involved in the control of embryonic stem cells differentiation; together with FLCN it is necessary to recruit and activate RRAGC/RagC and RRAGD/RagD at the lysosomes, and to induce exit of embryonic stem cells from pluripotency via non-canonical, mTOR-independent TFE3 inactivation (By similarity).
Subcellular location: Lysosome membrane {ECO:0000250|UniProtKB:Q6IAA8}; Lipid-anchor {ECO:0000250|UniProtKB:Q6IAA8}; Cytoplasmic side {ECO:0000250|UniProtKB:Q6IAA8}. Late endosome membrane {ECO:0000250|UniProtKB:Q6IAA8}; Lipid-anchor {ECO:0000250|UniProtKB:Q6IAA8}; Cytoplasmic side {ECO:0000250|UniProtKB:Q6IAA8}. Note=Recruited to lysosome and endosome membranes through N-terminal myristoylation and palmitoylation. {ECO:0000250|UniProtKB:Q6IAA8}.
Interaction partners:
- Ragulator complex protein LAMTOR4
- Ragulator complex protein LAMTOR3
- Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
- Ragulator complex protein LAMTOR5
- Neutral amino acid transporter 9
- Ras-related GTP-binding protein
- Ras-related GTP-binding protein
- Regulatory-associated protein of mTOR
- V-type proton ATPase subunit B, brain isoform
- Ras-related GTP-binding protein A
Sequence:
MGCCYSSENEDSDQDQEERKLLLDPSNTPTKALNGAEPSYHSLPSARTDEQALLSSILAKTASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVVQFGIP
Protein: Cohesin subunit SA (SCC3 homolog) (Stromal antigen) (D6W5U7)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286, ECO:0000256|RuleBase:RU369063}. Nucleus {ECO:0000256|RuleBase:RU369063}. Chromosome, centromere {ECO:0000256|RuleBase:RU369063}.
Interaction partners:
Sequence:
MSSPLQRAVGDTKRALSASSSSSASLPFDDRDSNHTSEGNGDSLLADEDTDFEDSLNRNVKKRAAKRPPKTTPVAKHPKKGSRVVHRHSRKQSEPPANDLFNAVKAAKSDMQSLVDEWLDSYKQDQDAGFLELVNFFIQSCGCKGIVTPEMFKKMSNSEIIQHLTEQFNEDSGDYPLIAPGPSWKKFQGSFCEFVRTLVCQCQYSLLYDGFPMDDLISLLTGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSVHQDNNQRQYEAERNKGPGQRAPERLESLLEKRKELQEHQEEIEGMMNALFRGVFVHRYRDVLPEIRAICIEEIGCWMQSYSTSFLTDSYLKYIGWTLHDKHREVRLKCVKALKGLYGNRDLTTRLELFTSRFKDRMVSMVMDREYDVAVEAVRLLILILKNMEGVLTDADCESVYPVVYASHRGLASAAGEFLYWKLFYPECEIRMMGGREQRQSPGAQRTFFQLLLSFFVESELHDHAAYLVDSLWDCAGARLKDWEGLTSLLLEKDQNLGDVQESTLIEILVSSARQASEGHPPVGRVTGRKGLTSKERKTQADDRVKLTEHLIPLLPQLLAKFSADAEKVTPLLQLLSCFDLHIYCTGRLEKHLELFLQQLQEVVVKHAEPAVLEAGAHALYLLCNPEFTFFSRADFARSQLVDLLTDRFQQELEELLQSSFLDEDEVYNLAATLKRLSAFYNTHDLTRWELYEPCCQLLQKAVDTGEVPHQVILPALTLVYFSILWTLTHISKSDASQKQLSSLRDRMVAFCELCQSCLSDVDTEIQEQAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFIQPGDLGSGDSQEDHLQIERLHQRRRLLAGFCKLLLYGVLEMDAASDVFKHYNKFYNDYGDIIKETLTRARQIDRSHCSRILLLSLKQLYTELLQEHGPQGLNELPAFIEMRDLARRFALSFGPQQLQNRDLVVMLHKEGIQFSLSELPPAGSSNQPPNLAFLELLSEFSPRLFHQDKQLLLSYLEKCLQHVSQAPGHPWGPVTTYCHSLSPVENTAETSPQVLPSSKRRRVEGPAKPNREDVSSSQEESLQLNSIPPTPTLTSTAVKSRQPLWGLKEMEEEDGSELDFAQGSQPVAGTERSRFLGPQYFQTPHNPSGPGLGNQLMRLSLMEEDEEEELEIQDESNEERQDTDMQASSYSSTSERGLDLLDSTELDIEDF
Protein: LP20058p (Q5U149)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MCSCSIRCCFLYSLIIFSFVYYYNDVVVDNIIFEEHHLVEKYSVDTKGCRMLTMVPNEYDVMFLWRGLRRDFCASNLNLTSFSNCTYNYLRTEVNMELAKARFGVETLESFKCMYYAMERHTDFDNRYLYSREFELLTDGNNTIEPHADIIRAECFINATSIYNGVHFYVHPTDEWLRTAQGLPPLKLASDVGSLSVLIVGLDSISQMHFHRSMARTANFLLSLPHVELKGFNRLGEDGFDSLMPLLSGLSGQELKDVSSNLSSLDSCPFIWKVFQKAGYETGLGEDNIDKSLFVKGFRKPPTDLYLRPALLEMWLKTRTDGLFGTHCNEKDNYAMVLREFLFKMLPHHTSHRFFTFLWWTQGIDHLFNYGRKLDQPFLKMFKAIGRSGLLKNTVLLVVSNHGLNKGRFYKKKKK
Protein: Segmentation protein fushi tarazu (P02835)
Organism: Drosophila melanogaster (Fruit fly)
Function: May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons. Required during embryogenesis for the process of body segmentation. Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:3049237}.
Interaction partners:
- Nuclear hormone receptor FTZ-F1
- Segmentation protein paired
- Homeobox protein abdominal-A
- Fork head domain transcription factor slp1
- Protein hunchback
- Huckebein
- Protein odd-skipped
- Zygotic gap protein knirps
- Protein sister of odd and bowel
- Protein bowel
Sequence:
MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDLYHLS
Protein: Immunoglobulin-binding protein 1 (Alpha4 phosphoprotein) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (O08836)
Organism: Rattus norvegicus (Rat)
Function: Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits (By similarity).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein kinase mTOR
- Regulatory-associated protein of mTOR
- Target of rapamycin complex subunit LST8
- DEP domain-containing mTOR-interacting protein
- AKT1 substrate 1
- Immunoglobulin
- Serine/threonine-protein phosphatase 4 catalytic subunit
- Serine/threonine-protein phosphatase 6 catalytic subunit
Sequence:
MAASEEELLLPRLPELFETSKKLLEELEVATEPTGSRTIQDKVSKGLELLEKAAGMLSQLDLFSRNEDLEEIASIDLKYLMVPALQGALTMKQVNPSKRLDHLQRAREHFIHFLTQCHCYHVAEFQLPQTKNNSAENNTARSSMAYPNLVAMASQRQAKIERYKQKKEVEHRLSALKSAVESGQADDERVREYYLLHLRRWIGISLEEIESIDQEIKILKDKDSPREESACQSSLPEKPPMKPFILTRNKAQAKVFGTGYPSLATMTVSDWYEQHQKYGALPDRGIAKPPSADFQRAAQQQEDQEQKDEENEEKALHRMREWDDWKDTHPRGYGNRQNMG
Protein: Adenylate kinase isoenzyme 6 homolog HBR1 (AK6) (EC 2.7.4.3) (Dual activity adenylate kinase/ATPase) (AK/ATPase) (Hemoglobin and proliferation-regulated protein 1) (Hb-regulated protein 1) (Q8TG40)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation (By similarity). Induces transcription of mating-type proteins ALPHA1 and ALPHA2 and moderately represses transcription of mating-type protein A1 in response to hemoglobin and growth signals. Involved in the induction of a high affinity fibronectin receptor by sub-inhibitory dosages of caspofungin.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03173}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03173}.
Interaction partners:
- Adenylate kinase
- GTP:AMP phosphotransferase, mitochondrial
- Adenosine kinase
- Adenine phosphoribosyltransferase
- Ribonucleoside-diphosphate reductase
- Ribonucleoside-diphosphate reductase
- Phosphodiesterase
- Nucleoside diphosphate kinase
- Rnr22p
- AMP deaminase
Sequence:
MTTMSRRYTPNIIITGTPGCGKSSHSSSLVSQLNQTLGKETTIHFKHFNISEIAKERDCIESYDAKLDTSIVDEDKLLDSLEPDLEKGGVVVDWHCCDIFPERLIDLVVVLRTDNSNLFDRLKTRNYNDLKLQENLDCEIMEVILQEAKDSYIPDIVIELRSDTAEEMDENVDRISSWVETWIEDHPDGVSNELNKQYNPDDSSDEGDDNSDSDEYELEEDEQEEEEEREEYDEETNEEMEHTEDIAQ
Protein: Cystathionine beta-synthase (EC 4.2.1.22) (Q2V0C9)
Organism: Apis mellifera (Honeybee)
Function: Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine.
Interaction partners:
Sequence:
MEFKQPNRPSYCTWELNATNSPHTCRTKNGDYTKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDSQNEVGFYEVEGIGYDFIPTVLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEEKRMVIILPDGIRNYLTKFVSEYWMETRGFLQPVCQNEMNKWWWNMKISNLSFDKQSLLKENTVTCQEAMHMLKNADSQLLVISDDNIHIKGVISLNKLTSYVISGIVKCTDFVDKAMVKQYVKVKHSATLGYISRVLEKEPYVIILDDEHDDAFIGIVNQFHILQFITKNGTSNNYLIN
Protein: UDP-glucuronate 4-epimerase 6 (EC 5.1.3.6) (UDP-glucuronic acid epimerase 6) (AtUGlcAE2) (Q9LIS3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- UDP-D-apiose/UDP-D-xylose synthase 1
- UDP-sugar pyrophosphorylase
- UDP-D-apiose/UDP-D-xylose synthase 2
- UTP--glucose-1-phosphate uridylyltransferase 1
- UTP--glucose-1-phosphate uridylyltransferase 2
- Sucrose synthase 3
- Sucrose synthase 5
- Sucrose synthase 1
- Sucrose synthase 2
- Sucrose synthase 6
Sequence:
MPLSATADTSKTVKLERYNSYLRKIHSTKVLNASSKVLFRATLLVALVLVLIFAINYPPLSDSRAAAAHHLHRRSFLSTGLFSSSSSSSSIGGAAWEKRVRQSSTAKRPHGLSVLVTGAAGFVGSHCSLALRKRGDGVLGFDNFNDYYDPSLKRARQELLEKQQVFIVEGDLNDGPLLRKLFDVVPFTHILHLAAQAGVRYAMKNPQSYIASNIAGFVNLLEVAKAANPQPAIVWASSSSVYGLNTENPFSEEHRTDQPASLYAATKKAGEEIAHTYNHIYGLSLTGLRFFTVYGPWGRPDMAYFFFTKDILHGKSIDIYRTQDNQEVARDFTYIDDIVKGCVGALDTAEKSTGSGGKKRGQAQLRVYNLGNTSPVPVGRLVSILEGLLGTKAKKHLIKMPRNGDVPYTHANVSLAYKDFGYKPTTDLAAGLRKFVKWYVGYYGIQPRVKKETSHAEDSA
Protein: Cyclin-dependent kinase 2 homolog (Cell division control protein 2 homolog) (cdc2-related kinase 2) (Q8IJQ1)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Cyclin 1
- CDK-activating kinase assembly factor MAT1
- RNA polymerase II transcription factor B subunit 4, putative
- Transcription initiation factor IIE subunit alpha, putative
- DNA 5'-3' helicase
- General transcription factor IIH subunit
- BSD domain-containing protein
- DNA 3'-5' helicase
- General transcription factor IIH subunit 4
- DNA-directed RNA polymerase II 16 kDa subunit, putative
Sequence:
MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNKISNYIDDCGINFVLLREIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQILNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLNLTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFLLGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAEDAMKHRYFFNDPLPCDISQLPFNDL