wanglab/gogpt-training-data huggingface dataset:
Protein: Protein disulfide-isomerase (EC 5.3.4.1) (A2QFJ8)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
Sequence:
MRSFAPWLVSLLGASAVVAAADTESDVISLDQDTFESFMNEHGLVLAEFFAPWCGHCKALAPKYEEAATELKAKNIPLVKVDCTAEEDLCRSQGVEGYPTLKIFRGVDSSKPYQGARQTESIVSYMIKQSLPAVSSVNEENLEEIKTMDKIVVIGYIPSEDQETYQAFEKYAESQRDNYLFAATDDAAIAKSEGVEQPSIVLYKDFDEKKAVYDGEIEQEAIHSWVKSASTPLVGEIGPETYSGYIGAGVPLAYIFAETKEEREKYTEDFKPIAQKHKGAINIATIDAKMFGAHAGNLNLDSQKFPAFAIQDPAKNAKYPYDQAKELNADEVEKFIQDVLDGKVEPSIKSEPVPESQEGPVTVVVAHSYKDLVIDNDKDVLLEFYAPWCGHCKALAPKYDELAALYADHPDLAAKVTIAKIDATANDVPDPITGFPTLRLYPAGAKDSPIEYSGSRTVEDLANFVKENGKHNVDALNVASEETQEGGDVTEAAPSATEAETPAATDDEKAEHDEL
Protein: Myosin regulatory light chain 10 (Myosin light chain 2, lymphocyte-specific) (Precursor lymphocyte-specific regulatory light chain) (Q9BUA6)
Organism: Homo sapiens (Human)
Interaction partners:
- Actin, cytoplasmic 1
- Actin, cytoplasmic 2
- Rho-associated protein kinase 2
- Rho-associated protein kinase 1
- Myosin-10
- Protein phosphatase 1 regulatory subunit 12C
- Myosin-9
- Myosin-11
- Myosin light chain kinase 2, skeletal/cardiac muscle
- Myosin light polypeptide 6
Sequence:
MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
Protein: Uncharacterized protein YjbG (P32688)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized lipoprotein YjbF
- Uncharacterized lipoprotein YjbH
- Uncharacterized protein YjbE
- Inner membrane protein YcfT
- Uncharacterized lipoprotein GfcD
- Uncharacterized protein YmgD
- Uncharacterized lipoprotein GfcB
- UPF0757 protein YmgG
- Protein CbrA
- Colanic acid biosynthesis protein WcaK
Sequence:
MIKQTIVALLLSVGASSVFAAGTVKVFSNGSSEAKTLTGAEHLIDLVGQPRLANSWWPGAVISEELATAAALRQQQALLTRLAEQGADSSADDAAAINALRQQIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQPFTPGRDVASYLSDQSLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVGLADSVWSETPDALNADILQTLTQRIPQ
Protein: Madf and zinc finger protein 1 (Protein clifford) (Q1LZ24)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000269|PubMed:38769058}. Chromosome {ECO:0000269|PubMed:38769058}. Nucleus, nucleoplasm {ECO:0000269|PubMed:38769058}. Note=Binds to specific bands on both euchromatin and heterochromatin regions of polytene chromosomes (PubMed:38769058). Roughly equally distributed between chromatin and the nucleoplasm (PubMed:38769058). {ECO:0000269|PubMed:38769058}.
Interaction partners:
- Uncharacterized protein, isoform C
Sequence:
MELCGNVMTNSKYEMFRLKCLYCSIESELKDWELFIVHVKSAHYCEDEDVRINEIKEDTEELYSVVDAADPAIAYGPDEFFEVIENSNGVDQWMEADSKDIQYEEDATAWSAATNNSWEFGPGGSSLELPAGKEVTQMDESSQNHIPLNTDDDDVDCSDFFMSEDDLAPPRKPGRPPRRTRPGQVFKFKVSFIRSNPRVLHLIQAYKEHPCLWNPSDEHYQDEPARSMAYEAIMERMDRKANVLFTVEELKKTLEQLHVQYTLALETKQRGKLVGLAARYFAKCEFLSVAPVVTPRENEEDNDLTAIKLNFKEENLITTSFIETYANYPVLYNQALPDFGSIEIRADAFKRMAKEFQPVVKANETDVYIAVNKLRRWLYDAIRRLKSKELIQKCSKQEVQYLQMCSFLPAKGSESQVLYCDYCDKRFHGDYNLRVHIVKAHEVGDLPYLCSFCPRRFDRHVDMDRHKLRSHFERKLKCQYCEKSFAVDTDLKVHTLIHTGERPHVCDICGKTFRLKLLLDHHVNGVHLNIRPYSCNMCTKTFRKKFELANHIKGHLNIRDKKCEYCDATFYDHSSLSRHRRSHRSE
Protein: DCD domain-containing protein NRP (Asparagine-rich protein) (N-rich protein) (GDA1-like protein) (Q8RXN8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Contributes to the initial phase of responses to abiotic and biotic stress signals (Probable). Binds FYPP3 and facilitates FYPP3 degradation to promote abscisic acid (ABA) response.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21277785, ECO:0000269|PubMed:28633330}.
Interaction partners:
- CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
- Nodulin-related protein 1
- Similar to part of disease resistance protein domain-containing protein)
Sequence:
MEYNNNNQQSFWQFSDQLRVQTPNLANLSLNDSIWSTNSVFKERRNLDIAATTDKNNNQIDYYQKKTTSDNINSNWNWKSSGSNNDMGLGFGPVGSKSTVDLNPIDKFNSPFNDTWKFNSVNVNVNGYSPSSAVNGDFNKGVYTSMKKYGYNVNLKNNNKNKGIDEDHQIQKGGKKNRKNQQNNNNQRNEDDKNNGLDKRFKTLPPAEALPRNETIGGYIFVCNNDTMEENLKRQLFGLPPRYRDSVRAITPGLPLFLYNYSTHQLHGIYEAASFGGTNIELNAFEDKKCPGESRFPAQVRAITRKVCLPLEEDSFRPILHHYDGPKFRLELSVPEVLSLLDIFADQNP
Protein: Paired related homeobox 1 (G3V2N3)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPRPAPRPTDYLSWGTASPYR
Protein: GATOR complex protein Iml1 (Increased minichromosome loss 1) (Q9W0E3)
Organism: Drosophila melanogaster (Fruit fly)
Function: An essential component of the GATOR subcomplex GATOR1 which functions as an inhibitor of the amino acid-sensing branch of the TORC1 signaling pathway. The two GATOR subcomplexes, GATOR1 and GATOR2, regulate the TORC1 pathway in order to mediate metabolic homeostasis, female gametogenesis and the response to amino acid limitation and complete starvation. The function of GATOR1 in negatively regulating the TORC1 pathway is essential for maintaining baseline levels of TORC1 activity under nutrient rich conditions, and for promoting survival during amino acid or complete starvation by inhibiting TORC1-dependent cell growth and promoting catabolic metabolism and autophagy. GATOR1 and GATOR2 act at different stages of oogenesis to regulate TORC1 in order to control meiotic entry and promote oocyte growth and development. After exactly four mitotic cyst divisions, the GATOR1 complex members (Iml1, Nprl2 and Nprl3) down-regulate TORC1 to slow cellular metabolism and promote the mitotic/meiotic transition. At later stages of oogenesis, the mio and Nup44A components of the GATOR2 complex inhibit GATOR1 and thus activate TORC1 to promote meiotic progression, and drive oocyte growth and development.
Interaction partners:
- GH04846p
- GATOR2 complex protein Wdr59
- GATOR2 complex protein Mio
- Protein SEC13 homolog
- GATOR complex protein NPRL2
- GATOR complex protein NPRL3
- GATOR2 complex protein Wdr24
- Nucleoporin seh1
- GH16429p
- FI04419p
Sequence:
MKLYKLNTHTRGCNKSYDADLVMNLKDHPNANVGDVVEIYAPDEENGTHLLLQITEFNGSCGRDVISIESGIANAFKMRPYSNVVMRIVKPADVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNERCDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNSSATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTSADDYSLPHWINLSFYSTNKKIVYSSFIPRIKLPLFGSQLTLHDGVGDGEGEENERHFLSCNQSEYKHNSLFDYDAYDEQIFQPLPAQSTCSLQRVVRAKKTSVPSLETYAYRNNDWENLTPTQIPAMRRKMSDPDIHHGTSAMLAALQPDTTNLSESLASEKNSRRTIVSIAPIVRPGRALINPFDPSQVTIKLTSNRRRWTHIFPKGPTGVLIQQHHYQAVPAKPTQAGQQRPLQQTQSNNNNDQEDYGCENGEQYDRVSSHSLLNKSDSSQSFVMGDEPIDFFKRRQNSPMNPQPANVPNLTATQAKSYLWGATGEQEWTPAITTVKHLRPIVEGEHHHLGSLEALRALDPPPDAEAGGGRGKIIIGVDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEKPPTASGCSSGSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYRFHAPQHETYEISGVNFTTEKLENFNWNHMDLYICTRGDVDYPLMESLKYWRYRMYLLPRENIVSKIASCQRCDIFPDVTADNTREQVEDFVRLIEAVSKLKRQYARKARYLASLLQDSPIAHITKRRHSTSIISRPQPNQGLTNSPFRERVGSNRLPEKRPSINVRPKLENGRIPRIFPATDAAAAAGVAARDDQDDGFPVDIKFSPNATLPEIFEAMKHPVNGVGFFSQTQSLPSCTFVSYDALMWLKTRLNNGRHPLDLLEAMRKERMICHASGDWKKPVVPGFVFYYVVQQDKNAKDYAPPLDDYSAFVNEWLEIEFQGCSFLWHDEPVTTPVPNFLRDSPAPQSWTETSSNKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVSVPADPMAEPFTKKSDPLRGPIFIPLCTTFLPNGAALFDEFPEESRSDRMLFFQEAILGKFGFLPCVLEKKYSVGKDLPKEYQYVHCTGNMFALIRCATNNYQVESPILKEANVTRCVYGHTNNTNVPKKVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFWTQSQELKRRAQKFEFNNNNTEENKMK
Protein: RNA polymerase II elongation factor ELL2 (O00472)
Organism: Homo sapiens (Human)
Function: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.
Subcellular location: Nucleus.
Interaction partners:
- AF4/FMR2 family member 1
- ELL-associated factor 1
- AF4/FMR2 family member 4
- Protein AF-9
- Protein ENL
- Cyclin-T1
- Cyclin-dependent kinase 9
- Cyclin-T2
- ELL-associated factor 2
- RNA polymerase II elongation factor ELL
Sequence:
MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
Protein: Small ribosomal subunit protein uS11A (40S ribosomal protein S14-A) (P0CT56)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS10
- Elongation factor 3
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein uS15
- mRNA export factor elf1
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein eS21
Sequence:
MATNVGPQIRSGELVFGVAHIFASFNDTFVHITDLTGKETIVRVTGGMKVKTDRDESSPYAAMLAAQDAAAKCKEVGITALHIKIRATGGTATKTPGPGAQAALRALARAGMRIGRIEDVTPIPTDSTRRKGGRRGRRL
Protein: Fe-S cluster assembly protein DRE2 (Anamorsin homolog) (P36152)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2. Has anti-apoptotic effects in the cell. Involved in negative control of H(2)O(2)-induced cell death.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03115, ECO:0000269|PubMed:18625724, ECO:0000269|PubMed:21700214}. Mitochondrion intermembrane space {ECO:0000255|HAMAP-Rule:MF_03115, ECO:0000269|PubMed:18625724, ECO:0000269|PubMed:21700214}.
Interaction partners:
- NADPH-dependent diflavin oxidoreductase 1
- Cytosolic Fe-S cluster assembly factor NBP35
- Monothiol glutaredoxin-3
- Cytosolic Fe-S cluster assembly factor NAR1
- Cytosolic Fe-S cluster assembly factor CFD1
- Monothiol glutaredoxin-4
- DNA repair/transcription protein MET18/MMS19
- Monothiol glutaredoxin-5
- Iron-sulfur clusters transporter ATM1, mitochondrial
- BolA-like protein 1
Sequence:
MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEENEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPINLDSISDDL
Protein: UBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37) (Q14CS0)
Organism: Homo sapiens (Human)
Function: Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P0C627}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P0C627}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P0C627}. Golgi apparatus {ECO:0000250|UniProtKB:P0C627}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q0KL01}. Note=Localizes to centrosome during mitotic prophase and metaphase. {ECO:0000250|UniProtKB:Q0KL01}.
Interaction partners:
- Transitional endoplasmic reticulum ATPase
- Tether containing UBX domain for GLUT4
- FAS-associated factor 1
- Deubiquitinating protein VCPIP1
- Phospholipase A-2-activating protein
- Ubiquitin thioesterase OTU1
- Derlin-1
- Protein VCF1
- Serine/threonine-protein kinase MRCK beta
- Protein phosphatase 1 regulatory subunit 7
Sequence:
MAEGGGPEPGEQERRSSGPRPPSARDLQLALAELYEDEVKCKSSKSNRPKATVFKSPRTPPQRFYSSEHEYSGLNIVRPSTGKIVNELFKEAREHGAVPLNEATRASGDDKSKSFTGGGYRLGSSFCKRSEYIYGENQLQDVQILLKLWSNGFSLDDGELRPYNEPTNAQFLESVKRGEIPLELQRLVHGGQVNLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTPEIVSTPSSPEEEDKSILNAVVLIDDSVPTTKIQIRLADGSRLIQRFNSTHRILDVRNFIVQSRPEFAALDFILVTSFPNKELTDESLTLLEADILNTVLLQQLK
Protein: Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4) (Q86WU2)
Organism: Homo sapiens (Human)
Function: Involved in D-lactate, but not L-lactate catabolic process.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q7TNG8}.
Interaction partners:
- L-lactate dehydrogenase A-like 6B
- L-lactate dehydrogenase C chain
- Pyruvate kinase PKLR
- Pyruvate kinase PKM
- L-lactate dehydrogenase A chain
- L-lactate dehydrogenase A-like 6A
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Hydroxyacylglutathione hydrolase, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
- NADP-dependent malic enzyme
Sequence:
MARLLRSATWELFPWRGYCSQKAKGELCRDFVEALKAVVGGSHVSTAAVVREQHGRDESVHRCEPPDAVVWPQNVEQVSRLAALCYRQGVPIIPFGTGTGLEGGVCAVQGGVCVNLTHMDRILELNQEDFSVVVEPGVTRKALNAHLRDSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVLNLEVVLPDGRLLHTAGRGRHFRFGFWPEIPHHTAWYSPCVSLGRRKSAAGYNLTGLFVGSEGTLGLITATTLRLHPAPEATVAATCAFPSVQAAVDSTVHILQAAVPVARIEFLDEVMMDACNRYSKLNCLVAPTLFLEFHGSQQALEEQLQRTEEIVQQNGASDFSWAKEAEERSRLWTARHNAWYAALATRPGCKGYSTDVCVPISRLPEIVVQTKEDLNASGLTGSIVGHVGDGNFHCILLVNPDDAEELGRVKAFAEQLGRRALALHGTCTGEHGIGMGKRQLLQEEVGAVGVETMRQLKAVLDPQGLMNPGKVL
Protein: Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (Q9VYA0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source (By similarity). Because of its role in energy metabolism, involved in the modulation of aged-related cardiac function, mobility, and lifespan.
Interaction partners:
- Nicotinamide-nucleotide adenylyltransferase
- Nicotinate phosphoribosyltransferase
- NAD-dependent histone deacetylase sirtuin-1
- NAD
- NAD kinase 2, mitochondrial
- NAD-dependent protein deacetylase Sirt2
- NAD-dependent protein deacylase Sirt4
- NAD-dependent protein deacetylase Sirt6
- NAD-dependent protein deacetylase Sirt7
- GMP synthase
Sequence:
MGRKVTVAVSTLNQWALDFEGNMVRILQSILEAKDMGASYRTGPELEVCGYSCEDHFREPDTFLHSWEVLLEVMMSPMCENMLVDVGMPVMHRNVAYNCRVAFFNRQILLIRPKMAMCDDGNYRESRWFTAWTKALQTEEYVLPRMIAQHTGQQTVPFGDAVIATRDTCLGYEICEELWNVRSKHIEMSLAGVELIVNSSGSYMELRKAHITSDLIRNASFKAGGAYLFSNLRGCDGQRVYFNGCSAIALNGEILARSQQFALQDVEVTLATIDLEEIRAYRVSLRSRCTAAASAAEYPRIHCDFEMSTHSDIFKTSTPPLNWPMHTPEEEIALGPACWLWDYLRRSGQGGFFLPLSGGVDSSSSATIVHSMCRQIVQAVQQGDAQVLHDIRQLLADSDYTPDNAAGLCNRLLVTCYMGSVNSSKETRRRAAQLANQLGSYHIEISIDSAVNALLSIFNAVTGLTPRFRTQGGCARQNLALQNMQSRIRMVLAYIFAQLTLWVRNRPGGLLVLGSANVDESLRGYLTKYDCSSADINPIGGISKMDLRRFLTYAKDKFNLPVLESIIDAPPTAELEPLQENGELQQTDEADMGMTYAELSQFGRLRKQSFCGPYSMFCHLVATWKSDLSPKEVAEKVKHFFLCYAINRHKMTVLTPSVHAESYSPDDNRFDHRPFLYRPNWSWQFKAIDDEAEKLQPIYTPSSAQLRPSSEDLLISTQRSSHLDDSKHSSPLSSASASASIDVGISTAAVPLPGAAAPGGLSKKPSGYSKVHVNVLGKIKDRTGIPV
Protein: Small ribosomal subunit protein eS8 (40S ribosomal protein S8) (Q54E24)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein eL13
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein eL29
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein uL22
Sequence:
MGISRDALHKHRLTGAARKCNYKKRKYELGRQAAKTKICSQGEEKRVRSIRVRGGHQKFRALRLDTGNFSWATEKITRKCRILNVVYNATSNDLVRTNTLVKGSIVQIDATPYKQWYETHYGVVVGKKKSAKKDGEAEQVVKKSASLLAKLASRAKGRVLDSAIESQIGEGRFFARITSRPGQVGKCDGYILEAKELEFYQRRLQKKKSAK
Protein: Two-component response regulator (Q94LW1)
Organism: Zea mays (Maize)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR036392}.
Interaction partners:
Sequence:
MTVDELKLQARASGGHGAKDQFPVGMRVLAVDDDPTCLKILENLLLRCQYHVTTTGQAATALKLLREKKDQFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSANGETQTVMKGITHGACDYLLKPVRIEQLRTIWQHVVRRRSCDAKNSGNDNDDSGKKLQVVSVEGDNGGVNRNKRISRKGRDDNGDDGDDSDDNSNENGDSSSQKKPRVVWSVELHRKFVAAVNQLGIDKAVPKKILDLMNVENITRENVASHLQKYRLYLKRLSADASRQANLTAAFGGRNPAYVNMGLDAFRQYNAYGRYRPVPTTNHSQPNNLLARMNSPAFGMHGLLPSQPLQIGHNQNNLNTSLGNVGGMNNGNLIRGAHMPLQDTSKCFPTGPSGNSFANISNSTQLVTTNNLPLQSLEPSNQQHLGRLHSSADPFNSFVGEPPQFADLGRCNTTWPTAVSSSNVQEIGQKDRIVNRPKLEPLSSFTEASSQIPLLGNEMQSHQVASLASNGLPMPFTQEAVPFAYGSSTNSREMLNNNLALSNSGVNSTLPNLRIDGSVVPGQTLGGSNSGGCVVPPLQDGRIDHQAVSSHLNYSNELMGTSRLQRGLSGGLDDIVVDMFRPDRADDGVPFIDGDWELV
Protein: DNA photolyase (Eurofung) (Q5BGE3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Benzodiazepine receptor family protein
- non-specific serine/threonine protein kinase
Sequence:
MRQKRKLSNGADERYHPNAQQTADFGIVLRDFYPPEMSNARCEAYNSGILERPIESWQKAYTETSAQQNAMTANAAVVHWFKSDLRLHDNRALQMAYRVAREHKIPLIGLYILSPEDLTAHLSSPARVDLTLRTLEQLKRDLGELDVPLYMETQACRKDIPRRIINLCQEWGANHLFANLEYEVDELRREAKLIRLCAENGIRFETAHDMCVVPPGVLSSQQGRQYAVYSPWFRSWLAFLNENPEYLEVSEDPTSNPGDARRYFKELFECPVPATPENKRFDDVEKADRVRRAFPAGEHEGLRRLEEFLEKATAYDDERNFLSGETTSKLSPYFASGSLSARTAVAKAREANAGKISRGEAGYISWISEVAWRDFYKHVLVHWPFICMNKCFKFEFTNIDWSYNNTHFEAWAAGKTGYPLVDAAMRQLHATAWMHNRCRMVVSSFLCKDLLIDWRRGERYFMEHLIDGDFASNHGGWGFGSSTGVDPQPYFRIFNPIRQSERFDPDGEFIRRWVPELRGVEGNAIHAPYERGAGDIARANGYPEPIVDHARQRGVALRKYKDAARGA
Protein: Frequenin-1 (d-FRQ) (P37236)
Organism: Drosophila melanogaster (Fruit fly)
Function: Ca(2+)-dependent modulation of synaptic efficacy.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9VWX8}.
Interaction partners:
- Phosphatidylinositol 4-kinase beta
- Peripheral plasma membrane protein CASK
Sequence:
MGKKSSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKFASLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQSEDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQALSLGGG
Protein: DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (Q9LSZ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR028763}.
Interaction partners:
- DNA-directed RNA polymerase III subunit 2
- RNApolymerase 14 kDa subunit
- DNA-directed RNA polymerase III subunit RPC3
- DNA-directed RNA polymerase III subunit 1
- DNA-directed RNA polymerase III subunit RPC9
- RNA polymerase III RPC4
- DNA-directed RNA polymerase subunit
- At4g25180
- SIN-like family protein
- DNA-directed RNA polymerases II, IV and V subunit 8B
Sequence:
MSKRKRPDPKSSGGDLNEPHEKKLLDLIRINQGRGATMFELKREKTIPATIVTRLIASLRKKNLIKEVANMNNKGVKHYLAMEFEPCSELTGGEWYTDGALDLSKIEDLKAKCVMILERHRQRVVTLEVLCGYFVKEEKLSVDQTKEILKNLILDNLIMEVKSNGMNEFASTRIGEVCYRLTGKKFGNGEPRAGAFASIPCGVCPHIAICSPDGVISPTTCVYFQKWLDF
Protein: Neuron navigator 2 (A0A0G2K833)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSVMLWRWEQNNSTMKLIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANDKIEDINGCPKNRSQMIENIDACLNFLAAKGINTQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQQPEKQHLSSSPLPPAGSQVAGAPSQCQSGILQQQGLATPQAPCQPLQPASHQQAKTQAEMQSRLPGPTARVAAAGSEAKTRGGSTAANNRRSQSFNNYDKSKPVPSPPQPAPPSNHEKEPLASSASSHPGMSENVPASLESSPSIPVNCSSSAIPQPSMTSKPWRSKSLSVKHSATSSMLSVKPAGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGSASRDTSCERLEILPSFEESEELEVANRAPPTAGPASSSPKIALKGIAQRTFSRALTNKKSSPKGNEKEKEKQQREKEKETGKDLTKRVSVTDRPDLKEEPKEELSGVVVTEMPKKSSKIASFIPKGGKLSSTKKEATAPSHSGIPKPGMKNMPGKSPSAPIPPKEGERSRGKLSSGLPPQKPQLDSRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSIGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSAGVSMEPSHYTKSGQPALEELTAEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFISAEAGRYVYSAPLRRQLASRGSSICHVDVSDKVGDEVDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRRNLDVQTDAEKHSQVERNSLWSGDDIKRSDGGSDSGVKMEPGSKWRRNPSDMSDESDKSVSGKKNPVLSQTGSWRRGMTAEVGITMPRTKPSAQTGTLKTSGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKTLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAPNQDDGYLSLSSRTNLQYRSLPRPSKSNSRNGAGNRCSTSSIDSNMSSKSAGLPVPKLREPSKTSLGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPATQPVSNSTQATLQPGTKYTDVASPTLRRLFGGKPTKQVPIATAETMKSAVVISNPHATMTQQGNLESPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSGPSNSLTWGTSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGGLSHNSSPGPVASTKEDSLMPFVRTSSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDTKEWFRSHSAGGLQETATNSPFSSGSSVTSPSGTRFNFSQLASPTAVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSAQATDLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNAHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSLGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEAMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTILVTVKGLTENSLDSLVFESLIPKPILQRYVSLLTEHRRIILSGPSGTGKTYLANRLSEYVVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNAELVKIINWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSLPREGSTSKQVPPSDTEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL
Protein: Sphingoid long-chain base transporter RSB1 (A0A1D8PU07)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MDLASITEWTPTTTPTSTTLSTIAATYVPALQSKLSNAIDTLTSKGSTIDIVDYISVSRIIRGAQASLSIISAQQVLATATNINTATATATDVQLQAQIQAQAQAIQIIWQATENLLDLAWEMNVYAIPKLNRVANILFLVIFAITFVMTCLMWIKSRYWWFNVSWTCGTALEFLGFLGRVLSFDDMTKFDYYLLQLITLTLSPVFLMAGIYFLFGQLVVIHGRQYSMLKPLHYSYIFITCDVVSLVVQAVGGGMTSIAAQRYENVDSGTYTMIAGIAFQVFSMSVFLTFWFVFCWNIYFRDISVNESKPSSYYQKKSLITFIKLLLNGDDANKYKLQVLDKHYNLGYQDLRGRPLYNYYAIAITSAVIAVYIRCVYRVVELAQGFRGYLITHEAYIMTLDAAMIAICCIIFMLFHPQFVMGSINVIGFRSIAKNQDQEMGDTSTEVKTNEMKSLV