wanglab/gogpt-training-data huggingface dataset:
Protein: Protein kinase and PP2C-like domain-containing protein [Includes: Probable serine/threonine protein kinase At2g40860 (EC 2.7.11.1); Probable protein phosphatase 2C 31 (AtPP2C31) (EC 3.1.3.16)] (Q940A2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein phosphatase 2C 32
- procollagen-proline 3-dioxygenase
- GDP-L-galactose phosphorylase 2
- Putative F-box protein At1g65770
- 60S ribosomal protein L36
- Inositol-phosphate phosphatase
Sequence:
MVMEIVKPNTCIRGCCTSESIPLHLPSSSFTLLSPIAKGSESVVYEAILDGRRVAAKKPILSTSDDLDKFHRNLQLSCNLNHPGVAKLLAAHAKPPNYMFFFDFYESGTLAEKLHVEEWSPSIDQVLLITLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVNLQNWRSSGKPTGGFHKKNMVGTLIYMAPEILRKDMYTEKADIYSFGILINELLTGVVPYTDRRAEAQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPKSLLSLIQNCWESDPSKRPSSDNVVLELESIWEQVRGKQQGHLLEKTSNSQSDTDGADIIKNSGDYRDTVNWFSQGECLSKKSSVSTVFDVKLWSSSTDEPSRYVPVISCGSFATCGRRESMEDTHFIIPHMCNEESIHLFAIFDGHRGAAAAEFSAQVLPGLVQSLCSTSAGEALSQAFVRTDLAFRQELDSHRQSKRVSQKDWHPGCTAIASLLVENKLFVANVGDSRAILCRAGHPFALSKAHLATCIDERNRVIGEGGRIEWLVDTWRVAPAGLQVTRSIGDDDLKPAVTAEPEISETILSADDEFLVMASDGLWDVMNDEEVIGIIRDTVKEPSMCSKRLATEAAARGSGDNITVIVVFLRPVSTAERIY
Protein: AP-1-like transcription factor YAP4 (Chromosome instability protein 5) (Transcription activator CIN5) (P40917)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcription activator involved in the regulation of genes expressed in response to environmental changes and metabolic requirements. According to genome-wide promoter binding and gene expression studies it regulates, among others, genes involved in ribosome biogenesis, and protein synthesis. It may also be involved in pleiotropic drug resistance. When overexpressed it confers increased resistance to cisplatin, the DNA-alkylating agents methylmethanosulfonate, and mitomycin C, the antimalarial drugs quinidine, mefloquine, and chloroquine, and increases cellular tolerance to sodium and lithium. Preferentially binds 5'-TTACTAA-3'.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Very-long-chain enoyl-CoA reductase
- CRE-binding bZIP protein SKO1
- Zinc finger protein MSN2
- Transcription factor SKN7
- AP-1-like transcription factor YAP1
- Protein SOK2
- General control transcription factor GCN4
- Zinc finger protein MSN4
- AP-1-like transcription factor YAP7
- Very-long-chain 3-oxoacyl-CoA reductase
Sequence:
MLMQIKMDNHPFNFQPILASHSMTRDSTKPKKMTDTAFVPSPPVGFIKEENKADLHTISVVASNVTLPQIQLPKIATLEEPGYESRTGSLTDLSGRRNSVNIGALCEDVPNTAGPHIARPVTINNLIPPSLPRLNTYQLRPQLSDTHLNCHFNSNPYTTASHAPFESSYTTASTFTSQPAASYFPSNSTPATRKNSATTNLPSEERRRVSVSLSEQVFNEGERYNNDGQLIGKTGKPLRNTKRAAQNRSAQKAFRQRREKYIKNLEEKSKLFDGLMKENSELKKMIESLKSKLKE
Protein: Packaging protein 3 (L1-52/55 kDa protein) (Packaging protein 52K) (P03262)
Organism: Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
Function: Involved in viral genome packaging through its interaction with packaging proteins 1 and 2. After proteolytic cleavage by adenovirus protease, L1 52/55k protein is removed from the capsid during viral maturation.
Subcellular location: Host nucleus {ECO:0000255|HAMAP-Rule:MF_04058, ECO:0000269|PubMed:1527852}. Note=Nuclear protein present in empty capsids and assembly intermediates. {ECO:0000255|HAMAP-Rule:MF_04058, ECO:0000269|PubMed:1527852}.
Interaction partners:
Sequence:
MHPVLRQMRPPPQQRQEQEQRQTCRAPSPSPTASGGATSAADAAADGDYEPPRRRARHYLDLEEGEGLARLGAPSPERHPRVQLKRDTREAYVPRQNLFRDREGEEPEEMRDRKFHAGRELRHGLNRERLLREEDFEPDARTGISPARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPNSKPLMAQLFLIVQHSRDNEAFRDALLNIVEPEGRWLLDLINILQSIVVQERSLSLADKVAAINYSMLSLGKFYARKIYHTPYVPIDKEVKIEGFYMRMALKVLTLSDDLGVYRNERIHKAVSVSRRRELSDRELMHSLQRALAGTGSGDREAESYFDAGADLRWAPSRRALEAAGAGPGLAVAPARAGNVGGVEEYDEDDEYEPEDGEY
Protein: DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) (Q1LZ51)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- DNA
- DNA
- DNA
- Histone-lysine N-methyltransferase EZH2
- Histone deacetylase 1
- E3 ubiquitin-protein ligase UHRF1
- S-adenosylmethionine synthase isoform type-2
- Adenosylhomocysteinase
- Histone deacetylase 2
- S-adenosylmethionine synthase isoform type-1
Sequence:
MKGDSRHLNEEEGASGYEDCIIVNGNCSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRRSSSRLSKREVSSLLNYTQDVVGDGDGEADDGDGSDILMMPKLTRETKDARTPSESPAVRTRNSNSISSLERQRTSPRITRGRQGRYHVQEYPVEFPATKSRRRRASSSASTPWSSPASIELMEDVTPKSSSTPSVDLSQDGPQEGMDATQVDAESRDGDSTEYQDDKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEIAADKLVALGLFSQHFNLATFNKLVSYRKAMYHTLEKAMVRAGKTFPSRPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNKQPEVHKSKVRRSGSRNLEARRRENKSRRRTTIDFAASEYSTPPKRLKTNSYGGKDRGEDEESRERMASDVTNNKGNLEDRCLSCGKKNPVSFHPLFEGGLCQSCRDRFLELFYMYDEDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAEDAKLQEPWSCYMCLPQRCHGVLRRRKDWNMRLQDFFTTDPDLEEFEPPKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKDLGIKVEKYVASEVCAESIAVGTIKHEGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFLACNPVMIDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEFSRTAKLKKVQTITTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE
Protein: LD22412p (Q8T078)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRKAQVQNSKEFEMAINALSGNLQASKTKNAPFKFRMKRCEFCNFKSESAMAMANHYETPHMNGVLYKCNFCTFEIRNATEIVYHMEAVHNIKARLIKPLPYHQCPNCGFEDNGKAKLARHQPVCAKKFRPELNLAPPNDWEAPAKIPRIKPRHGLVGTATAYQAMAAQAAAQKAALANIQQQQAAAQARNNLQAAALAAQNAAKMRQRAPQPPKQNIVRNPAPVRGGNAMNAGLSLPNSYQLAAGQLVQASKKPMAGQPSISITPLPRQSSVGAGAGASSSKAPQAAAGMKPGQSPSGNNKAQFVICEICDGYIKDLEQLRNHMQWMHKVKIHPKMIYNRPPLNCQKCQFRFFTDQGLERHLLGSHGLVTSSMQEAANKGKDAGRCPVCGRMYQWKLLNHVSRDHHMTLKPAHLSYKCTVCTATFGMYKQFETHVYTAHSTVARKAMDSKKNSAQSSGSGSGAGMSRSSLGAANDSLLKPLKINDEITIIPQPASKPRITNMESHVID
Protein: Solute carrier family 18 (Vesicular monoamine), member 2 (Solute carrier family 18 member A2) (B0JYP2)
Organism: Bos taurus (Bovine)
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000256|ARBA:ARBA00004644}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004644}.
Interaction partners:
Sequence:
MALSELALLRRLQESRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIEHEKDALEIQTAKPGLTASAPGSFQNIFSYYDNSTMVTGNSTDHLQGALVHEATTQHMATNSSSASSDCPSEDKDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFTGFCIMFISTVMFAFSRSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLRDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSHKWQLGVAFLPASVSYLIGTNVFGILAHKMGRWLCALLGMIIVGMSILCIPLAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNSSQSHPIGEDEESESD
Protein: Conserved oligomeric Golgi complex subunit 1 (Q586L0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395}.
Interaction partners:
Sequence:
MSSEEAIQEVRRIFTNNSVDQARDYLSRITPGIQESDERLKQLVGQSYRGLVAACDQVVVVEQACRKLLRLQKQMQEEKKQQQLENQYSQSRLTMPQSPRGVSSPVLRTISPHGGKSPRAKNVGEGKTQTSRHMGHSSSASPPVSEVVRSPLPHEATATLKGVCEETPRGGREGADDRQRDVLIYTQQCAALEGLLGARKLYDAAALLLQIRRERKQPHEKLAVESYEHRLKRAVRGLLREDAEQAAQSALSVANANRNDSGGGDLSLTSSTNMFTSSGGVEFMGRATGWKSDLSRALAHMTEVHKALGVLSHATVNDALLLLIDTIHDMIKTDLDHVVAALKGTSFTQAAAVDTNTDDGRSLRPLRRMEWLRAALELPPYLRSEGTSAPRVPALAKDANSSTEARVNARLVVSEATVALHIVQRAQHLFSHLVLYVASVLYSPSGPAREGRGTNGSRGGEQPDEVSAGELDAYVDSQRRRYALQGLLALRSKLTSQESNTEGDNETSGTGRAKSVRMSGSLAREALSASQRGGSIASATDDSEKKDGDSKCGSLDASSSMVGLNQDGERRSRHRTLYLCEVMRQVCGMQILDPLPLQWGFSSFSSNEKIAKCSGVSGDETAVFSKVGHQLRAVQELALQLLLHVSGAGLLNDPRTISLQQHLARQQGKMLQDMLLSSAQEGSNLTVSGGAAVNLFDARKWGEAVRQATESALLKTVGAALKRADRVCGAILKHISEGKGYKSTVVASAEEQPPQQQKQEGPPSVTTFAQKVLQRSIFFSESTSFGLLHTDQMTCMVPCSSFGGGDENKRNVASAEKGENLNAALARGIMQCTAIKSKTTPKEGRLPANLSSKAGCRASGGNVNKDKGGWVMQTVETDAGSDDNLFSVDEGEEERTVAMEKASDKSEKGVTDAVDDDSSAALKFGSLYSMLQRIFEVERTWSDSHPTLSVLVGEWFTNILQQVRKLLKHHTGQLQKWEELNVEGNCFEAKVTVMAALNRISMLVEVLLQVLEVAAPRNVASTLPMELREAIVTCHTPWVKLLRSEWEDGVRHAYRRAFAPEHLFARSKTPLNSSATTLDPNKRTSCINGQQLMLEYATCWSCSTPDGVQCESQKVTKHPTHVTPHVNELIFQVQHMLFKNGVNKRLRATVLPMVINELLDGTSSALLNAVLPWIREIAAVNRSGNAGKSGDSAGDNDELLFQVYFDSLYISGLFSIDGNSRAPTPSITAVLRTIEGWVNPTSWLVISPLLLQASDRLLRVTALSFGSWNPKALEEVWTAKGTGDSRTSLKGERTVAGDISITKEKPRFPLLPLIFTPSKVLGSDIVDGGVTKTAVFAFNKSSSVAVGVRGDSGIIGGLSATSLQRGTGALVGSALGSPSKPTSSNRFDGKVKGWMGSLW
Protein: Zinc finger protein ZFPM1 (Friend of GATA protein 1) (FOG-1) (Friend of GATA 1) (Zinc finger protein 89A) (Zinc finger protein multitype 1) (Q8IX07)
Organism: Homo sapiens (Human)
Function: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Erythroid transcription factor
- Endothelial transcription factor GATA-2
- Histone-binding protein RBBP4
- Rhombotin-2
- LIM domain-binding protein 1
- Histone deacetylase 1
- LIM domain-binding protein 2
- Transcription factor GATA-4
- Krueppel-like factor 1
- Transcription factor GATA-6
Sequence:
MSRRKQSNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK
Protein: Immunity factor for TNT (IFT) (Tuberculosis necrotizing toxin antitoxin) (TNT antitoxin) (O05443)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Antitoxin for tuberculosis necrotizing toxin (TNT). Acts by binding directly to TNT, which inhibits NAD(+) glycohydrolase activity of TNT and protects M.tuberculosis from self-poisoning.
Interaction partners:
- Outer membrane channel protein CpnT
- Pullulanase
- ESAT-6-like protein EsxF
- ESAT-6-like protein EsxE
- Transglycosylase
Sequence:
MTIGVDLSTDLQDWIRLSGMNMIQGSETNDGRTILWNKGGEVRYFIDRLAGWYVITSSDRMSREGYEFAAASMSVIEKYLYGYFGGSVRSERELPAIRAPFQPEELMPEYSIGTMTFAGRQRDTLIDSSGTVVAITAADRLVELSHYLDVSVNVIKDSFLDSEGKPLFTLWKDYKG
Protein: Probable glycosidase crf2 (EC 3.2.-.-) (Crh-like protein 2) (Q4WI46)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
- Cell wall mannoprotein 1
- 1,3-beta-glucanosyltransferase gel1
Sequence:
MVRIGSSLLLATLAATTVSAASDPPKCSQDSHCPEEWPCCSLYGQCGTGAYCLGGCDPLMSFSLDSCTPEPICQGKTYKDWSNLDNLASNTKYLGDASKSDWVYSGYPKVEDGNLLLTMPKNSVGTLIANNHYIWYGKITAKIKSSRGAGVVTGFILLSDTKDEIDYEFVGADLTNVQTNYYFQGVLDYNHGGNASVSGGNTFGDWHEYTIDWKPDAITWSVDGEVKRTLKKESTYNETSKQYMYPQTPSRMQLSLWPAGQASNAPGTIAWAGGEIDWDSEDIKDPGYYYATFGEITVECYDPPSGADIKGTKAYIFKDKAGLESSVQITNNKTVLASFGATGLDMDVGASSSASGSANKTSSSANTVPSGNGGSGNEPGNSHSGSSGSGTSTSDGSGSSTGFSQGSETSASSNKNAAPSQNERVLNGSFFAVLVAVVALVTL
Protein: Small ribosomal subunit protein uS15m (28S ribosomal protein S15, mitochondrial) (MRP-S15) (S15mt) (DmMRPS15) (Protein bonsai) (Q8WTC1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Essential for gut mitochondrial activity. Might be involved in tissue specific growth factor production.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14651932}.
Interaction partners:
- Mitochondrial ribosomal protein S11
- Small ribosomal subunit protein bS6m
- Large ribosomal subunit protein bL20m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS10m
Sequence:
MNKLLNIAQAGHRQFVREYAFKSDLKIKWMRPEKIACYKPEKSGDLAKLPPLKADELLPEYRDCKELDKADESVKSLFKLSNNASYLTTKFYRDEMVKEVQRHAQDFGSMEAKLAKMTAVIRRYQEHMDKHPRDKMIKVRLKELIDKRKKFLKYLRRWDYPRFEWILEKLDLVYKPPPTHFHWITRKESLQKLTDIYCENLKEERLEAYHKQLQAQQIPFLEEAIKKMQFVRQEQISCDVPVTVTEEKIADSKRQLEMLKELQQAEAAASSKKQNEDGFN
Protein: Olfactory receptor 11L1 (Q8NGX0)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
Sequence:
MEPQNTSTVTNFQLLGFQNLLEWQALLFVIFLLIYCLTIIGNVVIITVVSQGLRLHSPMYMFLQHLSFLEVWYTSTTVPLLLANLLSWGQAISFSACMAQLYFFVFLGATECFLLAFMAYDRYLAICSPLRYPFLMHRGLCARLVVVSWCTGVSTGFLPSLMISRLDFCGRNQINHFFCDLPPLMQLSCSRVYITEVTIFILSIAVLCICFFLTLGPYVFIVSSILRIPSTSGRRKTFSTCGSHLAVVTLYYGTMISMYVCPSPHLLPEINKIISVFYTVVTPLLNPVIYSLRNKDFKEAVRKVMRRKCGILWSTSKRKFLY
Protein: Secreted frizzled-related protein 3 (Frizzled-related protein 1) (FrzB-1) (Q9W6E0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Low density lipoprotein receptor-related protein 5
- Protein Wnt-5b
- Protein Wnt-8a
- Protein Wnt
- Dickkopf WNT-signaling pathway inhibitor 1b.
- Wnt inhibitory factor 1
- Protein Wnt
- Protein Wnt-11
- Protein Wnt
- Protein Wnt
Sequence:
MQNMFSYEMFICVLAFACLLEIPRGTGAASCEPIRIPMCKSMPWNMTKMPNHLHHSTQANAVLAIEQFEGLLGTQCSADLLFFLCAMYAPICTIDFQHDPIKPCKSVCERAKCGCEPVMKRYNHTWPESLACEELPVYDRGVCISPEAIVKAEGPDNSYYQDPAKCNPEGNPDFPMDSHNTNCKGANDRCKCKSVKFNQKTYSKNNYNYVIRARVKEIRIRNHDLSAIVEVKEVLKSSLVNIPRDTVTLYYNSGCLCPPLTANDEYIIMGYENEERSRLLLIDRSIAQKWKEKIGRKVKRWDQAANGRRTKWNHH
Protein: Mitochondrial transcription termination factor 1 (cDNA FLJ51270, highly similar to Transcription termination factor, mitochondrial) (B4DPR9)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MAPGNLWHMRNNFLFGSRCWMTRFSAENIFKSVSFRLFGVKCHNTDSEPLKNEDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIASIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILERSPESFFRSNNNLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAGLSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLVLICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIFLAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCNLSTLNITLLSWSKKRYEAKLKKLSRFA
Protein: Cry2 protein (Q99JJ1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
EGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQAGSISNTGPRALSSGPASPKRKLEAAEEPPGEELTKRARVTEMPTQEPASKDS
Protein: Transforming acidic coiled-coil-containing protein (Q553N8)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Putative mediator of RNA polymerase II transcription subunit 18
- Putative mediator of RNA polymerase II transcription subunit 14
Sequence:
MDNEKLKRFQERYELELIGVEDNNDEDIEYYRFKESLENGGDGISAIQNGGDGDGDGNQDKSDADLEYERQAQIALQQQQEKQRLMELEIQREYERLAAEGQAVEQDFDYEAEERKRQEESRKRFLERQNRNKPSPKKKTPEEEEKERIKLEKQKERDQQRELMRQAMSGSSNSKKETPLEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTKPKSPSPPPPQQQAEEPISQPTLNDDEYERQAQIALQQQQEKQRQMELEIQREYERLAAEGQGVEENIDYEAEQRKREEESRKRFLERQNKSKGAAKQKTPEDEEKERIKLEKQKERDQQRELMKQAMSGSGTPTKESKQEESKPSQNDQPISKPKSPSPIPPPQQQQQPPPEEPISQAPPTDDEYERQVQIALQKQQEKQKQMELEIQREYERLAAEGQGFEEIDYEAEEKKRQEESRKRMLERQNKSKGAAKQKTPEDEEKERIKLEKQKERDQQRELMKQAMGSGNNTPKKEEPKPIEEQSKPPTSQPKSQSPPPQKVEEPISQAPPTDEEYERQAQIALQQQQEKQRQMELEIQREYERLAAEGQGVEQDFDYEAEQRKREEESRKRFLERQNKSKGAAKQKTPEDEEKERIKLEKQKERDQQRELMKQAMSGGGGNGTPKKEEPEEVSKPKEVSKPKEVSKPSSSPSPPPQVEEPISQAPPTDEEYERQAQQALQQQQEKQRQMELEIQREYERLAAEGQGVEENIDYEAEERKRQEESRKRFLERQNKSKNPAKQRTPEDEEKERIKLEKQKERDQQRELMKQAMSGGGGTPKKETPKSQEEQSKPIEEQSKPKSPPPQQQQQQIEETTSQPTSNDDEYERQVQIALQKQQEKQRQMELEIQREYERLAAEGQGVEENIDYEAEEKKSQEESRKRMLERQNKAKGAAKQKTPEDEEKERIKLEKQKERDQQRELMRQAMSGVSNGESPVKKDKQSSSSSSQKPSEEESKSDQPTTKSKSPSPQPTENNNNNNNNNSNEDDEYERKAAIALKQQQEKQRQMELELQREYERLAAEEGKSPEPTPEEIEAEQKKKEEEMKRRFQERQKQSTQKQKTPEDEEKERIKLEKQKERDQQRELMKQTMSGGDPNGKSQQQKQSQPLPEEPPKPISQPQTTQPKPLSPSQQQQQQQQQQPQPQQQPQSQPQLQSQPQSQQHQPISSQDGFNLQSQQYYQQMQQQQQQFYQQFNQYNHPSSPNHHNQQQQPMYHQQNQSPSHNNNNSNNSSNISSPPPPTHQNMYPYPHQFYYPPPHQNMFTQEDIDRLLEKQKKEILKQCSDENAILSLELEDLQLKLEKEQRNCLSLKGILSQYEATMKKMIDQPAPVPQNSAKLSEALLDNEQLRKQIIDLKESNLQANKENQIHVSKFNALKAHAEAKLDSASEQLTKLKEVAKKEIEVLTIKLNRSESKVSIKEKENDELVKLCDELIFKLQTNQK
Protein: SH2 domain-containing protein 1A (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP) (O88890)
Organism: Mus musculus (Mouse)
Function: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2. However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1 (By similarity). Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation. In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Signaling lymphocytic activation molecule
- Natural killer cell receptor 2B4
- Tyrosine-protein kinase Fyn
- SLAM family member 6
- T-lymphocyte surface antigen Ly-9
- SLAM family member 5
- T-cell surface glycoprotein CD3 delta chain
- CD48 antigen
- SLAM family member 7
- Inducible T-cell costimulator
Sequence:
MDAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKVKNLISAFQKPDQGIVTPLQYPVEKSSGRGPQAPTGRRDSDICLNAP
Protein: Serine/threonine-protein kinase PDK1 (EC 2.7.11.1) (J9VH94)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Serine/threonine-protein kinase that functions in the sphingolipid-mediated signaling pathway, regulating organization of the plasma membrane (By similarity). May phosphorylate PKC1 to activate the cell integrity MAPK cascade during cell wall and membrane stress. May regulate sphingolipid metabolism upstream of YPK1.
Interaction partners:
Sequence:
MASSHFGPASPASSTPPPSSAYARLIAPTITRNSSSSSSRSTTTCSSTSSVQAVPMRPPPIETSTAATSRSQLPSNRHSENEAEHDTSYTSPGLSVGGRGGLARNGPRSNRLGTSPQARHVPPSIVALSPSPSPILNMASKRQSNTETVSGTSPSTPLGKSFLAQQDLSPNSSTIPLRVTISVDPNDRLSHDRESHSAERPRSSGNSPVRGRHGHLSTPSSPTNSYRALGGKPRTLSVDAGQNWGGSHRSRARDGDDRERRQSQVSSASSGALKKHSLDDWVLGEELGVGSYSTVYCVTPSANTHSPTSPQPARKYALKVINQAHLIQEKKVKYAMVERDALIRLSDPRPSKGHKRGVSSSSSSGYAQTGSAGKRRSTASIGGQSSMASVSGGTVSNSKKDTRDRLSIVTTSSAASSPVLTASSGSTQLSPTAVSGGGGNIKGRRPSRSAEPPTPVQEQTEMLIRGGEDGKDGQDGQETPSREWDRDRDWDNMTRSRPPSPVREESAEGGEKEKDEEERSGAEPVELGAAIHLTLPPPQIPSTPEPRGSPLLSTDGHRTSRETPRDRPHLTPKRRRQSLAPSERSVKSASTTGKMSAAAHPGVVRLYSTFNDSSSLYFVLSLASNGELASIIRKHGSLDITSARYYAAQLIDTLEFVHSRGVIHRDLKPENILLDEDMRIKITDFGSAKIIAKDEPIVDDSSRSRSFVGSADFVSPEVLRNEVATTASDIWAFGCVLYQFICGKPPFRGATDYLTFQKILKREVEFPKGIDEDAKSLIDTILDLEPNLRPSITFIKTHPFFQSIDFSTLWTIPAPPISSGLREPSKSTTLAQLEASDIWGVFEGSDVGEEDEDGFEYDADTVSPRPEGGAVGEGMMEPLFDRRAAASAVHNVDHPKFSRLRNQYINLGEDLDPPRPAYAGAGTGGRGKREKEVEKKKGEKARGLSHGSESSGGNRSALAGWLEAIKFGGAGGGGMSGSATSVAASDTVRTPGTGTGTGPGSRPGSRAGIPSFGLGPGSGSRSNRGSGASMRSDEARDLSMSLGGLRMNMSKASEFDKWTPLLLANESIIFTSPITLRTSSPALQLHLPAFLLPAPKKRQLVLTDFPRLLMIKDDNEADGDPAGSDSGAGLSSSSHVESGGGGVGGGGRGGGHGSLRIKGEAVFVPRPSTATGSSTTKGGGYSAVPNAVMDVQEKGSKGFTVQTPGMVYYCHVDSVELRAKWMAAIHRVGL
Protein: Isonitrile lipopeptide synthase (EC 2.3.1.-) (EC 6.2.1.-) (Q10896)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Polyketide synthase Pks13
- Phenyloxazoline synthase MbtB
- Acyl carrier protein Rv0100
- Phenolphthiocerol/phthiocerol polyketide synthase subunit C
- 
- Mycoketide-CoA synthase
- Mycocerosic acid synthase-like polyketide synthase
- Probable multifunctional mycocerosic acid synthase membrane-associated Mas
- Phthioceranic/hydroxyphthioceranic acid synthase
- Uncharacterized PPE family protein PPE1
Sequence:
MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVLENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL