wanglab/gogpt-training-data huggingface dataset:
Protein: Actin-related protein 2/3 complex subunit 3 (A0A8I5ZU90)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR016315}.
Interaction partners:
Sequence:
MPSSGAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSRSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKPASKQEDETMRAYLQQLRQETGLRLCDKVFDPQNDKPSKWWTCFVKRQFMNKSLSGPGQ
Protein: B box-type domain-containing protein (Q54PB6)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MKSSKIHNCEVCDKIYEEPQSLSCGDTICKKCVEKEKSQQQNKTKFNCPLCKEEVSCHFLNKRMNSEVIEFKKSQCKIHPNEKIISYCDNCNCNICKECSTSSNHRGHIFSTMNESKFELIFNEFSNNQYQKLLEYKQQVANSSELLKDNFKRTNDHSSTQLALLESTFSQLHSTLKTLETQLDFQIKKTNELNQISNTKFTTLITDVESNINNIINKNDQYFSKENSEQYKSTTPGTSDKIKQLFETNQIAIINDLTDTNNLLNNKSNINSNDFIKSSLIINNDNLLKFNEFLNSIFKIENIQQQSQQVQQTQQPQQTQHAQQAQQAQQAQQAQQTQHAQQTQQQQNIISHDNSRTISKSSSMDLNNNNNNNNNDDTNSNSSNSSAVSTPSNLPLSKSQSVNNIVKLGNSRSEYTPSITKSTSNSSIKSSNSDEISSTLQQFPSTIISSIPSPNRISKMYSSTNNLSGTVAAKDNTADIFRWNIVDPIPPNTTSICVISTKTQIPAGSIPKKVTSIVFSGYNQPLEEGSIPDTVLNLHLGQDYHQELKENVLPSSITSLHLGGKFNKPLKPGMIPFGVLDLHIGDSFNQSLSSNSLPSSILSLHLGGHFNQKLKQGDIPSSVSKLILSNDFNQQISQDVIPASCKTLIFGYAFNQVILPGVLPPNIDVLELSYSFNQVLVKGSIPDVRKLTFGYFFNKPIKSDGIIPKSVTHLTYGSLFNQTLTKYVVPKSTTLLTLPDTYASGRTSEISNLSSTCLVSYKPRDY
Protein: Thyroid adenoma-associated protein (Zgc:113068) (Q5BLB0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MVVKKKAPKVEAFVLDDVKLKSLTDSLSMEGDCKSTELAQLLKDSLSSFDPVEQIQLISKAGCMLEQLKEDESPSSPLLEACLHTLSFLYITLPAKNPLKRAVSSALGSGPDWLQEQMVRCLSEGLSAAFSSASTDHFSNLTDSITSCLSGFLIGEKCVHHLLTEVLQFFQKALNYYVEQNRILVGCHVAQAQLMQYSLAAVKASMLVVQQSQEPISAAVLSASSDQSDLYQALSGLLNCYTCVLTDEEFVQAVQSTAGMAAVLLIRSLLGNGDNLHFIVAGLLQCSVDAGSTPQWLRKSCAGLYESSRPAAVALYLSHGALAMLSWKGKTLSPQAVKLLLLIPDVLLSLHTRYRMITITFTLK
Protein: Probable peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29) (Q8BW00)
Organism: Mus musculus (Mouse)
Interaction partners:
- Obg-like ATPase 1
- Large ribosomal subunit protein mL62
Sequence:
MRRSWALSRQVSEARFPGKRWLVAGLGNHGMPGTRHSVGMAVLGQIARRLGVAENWTRDSRCAADLALAPLGDAQLVLLRPRRLMNVNGRSVARAAELFGLTAEEIYLVHDELDKPLGKLALKLGGSARGHNGVRSCISCLNSNAMPRLLVGIGRPTHPNMVENHVLGCFSPEEQELLSPLMDQATDLLLDHIRARSQGPLSGL
Protein: Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1) (Protein max-1 homolog) (Q00IB7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Critical component of the guidance pathway underlying endothelial cell migration and blood vessel patterning. Involved in mediating membrane localization of ephrin proteins, which have been shown to provide guidance cues for endothelial cell migration.
Interaction partners:
Sequence:
MAEVMESVSTAVVPNSSVDWQKRCIALETQLMRFRLQAGNIRHLLAERMQELEQRVIEADQRAESAEKQVHIMEEKLKSANMQPSETENSLYRSYQELSNQIQEKDLIVKRLEGQLEKQNLVRAQEAEIIEEKAAKIKDWVTFKLREMETENQQLKKANLKQTEQILMLQDKLQTLLERPMSPAVDTHLVPSSPLHPPSCPGTPPAQEDCWRLPGCRLNSSADSKRKITEGCDSAFHSASLLPMLQDKADSPKSSQDGVDATSTVKESAEGVEPSFGVMRDRAMGGASDRDHSSDELNSKFRSQCLRSSSSSSSSSSSAYETPGPGGFDTPTPTPKSPPPVSLSPPLTRLPLSCPFPLALPLGTSMTLPKVRTPLTPRDSIQLVKKHHSQPQPGLERLHQVNVSIDIGNCGSPSCHSLVPGSAPSHGLEETDIDEGTPESMEVVVEGSEITEAQPNDGDLLDGLTKELEMMDPEALKPPTPPLHRFPSWESRIYAVAKLGMRVSEACLGAKTIGRVSTQPQHSTTGPFTHLIYKNISVPVYSTLKGKATQISSVPLPDDDSGSEDDSSSLASLHTSTLGPDKKGSTPGSPRAVKRGVSTSSISSESDYAIPPDAYSLDSDCSEPEHKVQRTSSYSCESVGPETLEKTGYLLKMGSQVKAWKRRWFILRNGEILYYKSPSDVIRKPQGQMELNSSCHIARGEGAQTFQLITEKKTFYLAADSPNILEDWIRVLQNVLKVQASGPISMDKEVKPTARGWLTKVKHGHSKLVWCALIGKVFYYYRNQEDKFPLGQLRVREARVEEVDRSCDSDEDYEAGGRGFLSSHFTLVVHPKEQSPTYLLVGTKQEKDTWLYHLTVAAGSSASLRVGTEFEQLIGKLLDVDGVSDSALWKREVLCFSKEGLRYPLTTLPSEALQTEAIKLFKSCQLFINVLVESPSIDYHTSLAQNALQVCLTHPELQNEMYCQLIKQTNCRTPHNYALTQCWQLLSLCVALFLPQHHFLWYLRQYLQRNADPRTEVGKYAVYCQRSVERTLQNGEREAKPSRMEILSILLRNPYHHSLPFSIPVHFMNNTYEVVGFDGSTTVEEFLNTVNQRTGMRKPQISGFALFTDDPSGKDLEHCLQPANKICDVISKWEQALKELHPGKYEGTRTVRLTYKSRLCFRAQAKGETERERLLLAYQVNDEVLQGHFPVSKELALEVAALMAQVEYGDLDRAAMSPVGSPQPKTQQTLLQVLERFYPKRYKQECSVEQLRELGERLVATKWSVLRGCTASECVRIYLTVARKWPLFGAKLFNAKPLPPSSLDRTQVWLAVNEDGLSVLDYTMYPLVTYPYQSVITFGGCKEDFMLVVSLIKDQALGKKTVDKLLFAMAKPKILELTLLIASYINYWTSSLPGASNQTQSSTLGAQGDKKLWDIDSRHFPSMTYTTKGPTLL
Protein: Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) (A0A8I6A1U8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion {ECO:0000256|HAMAP-Rule:MF_03220}.
Interaction partners:
Sequence:
MAASMFFGRQLAAAALRSHRSQTTVRATAQALGSSGLFNKHGFQMQQQQQQQRSLSLHEYLSMELLQEAGVSVPKGFVAKSSDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFTSGLKGGVKIVFSPEEAKAVSSQMIGQKLITKQTGAKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSQGGVNIEDVAAENPEAIVKEPVDIIEGVKKEQAVTLAKKMGFPSNIVDSAAENMIKLYNLFLKYDATMVEINPMVEDADGKVLCMDAKINFDSNSAYRQKKIFALQDWSQEDERDKDAADADINYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKRVQAILVNIFGGIMRCDIIAQGIVMAVKDLEIRIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVSGRSCSVDMVVVCRGL
Protein: Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNAPII complex component SRB7) (C0LU16)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for embryo development and defense against necrotrophic fungal pathogens.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 10b
- Mediator of RNA polymerase II transcription subunit 23
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 7a
- Mediator of RNA polymerase II transcription subunit 10a
- Mediator of RNA polymerase II transcription subunit 7b
- Mediator of RNA polymerase II transcription subunit 22a
Sequence:
MDIISQLQEQVNTIAAITFNAFGTLQRDAPPVQLSPNYPEPPATTTVTDDATPFPEQPKQLSAGLVKAAKQFDALVAALPLSEGGEGAQLKRIAELQVENDLVGQELQKQLEAAEKELKQVQELFGQAADNCLNMKKPE
Protein: E3 ubiquitin-protein ligase TRIM45 (EC 2.3.2.27) (RING finger protein 99) (Tripartite motif-containing protein 45) (Q6PFY8)
Organism: Mus musculus (Mouse)
Function: May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9H8W5}. Nucleus {ECO:0000250|UniProtKB:Q9H8W5}.
Interaction partners:
Sequence:
MSEIRKPLLGFVHKLQDANASGSSGKTHCPTCLRLFKVPRLLPCLHTVCTTCLEKLDPFSVVDIRGGDSDTSSEGSVFQDPELCSLQPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVLLENLRGEGQGLVCDLCSDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSQVGKPILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLRDTQPHVEALEDALAQIKSVNNALQERVEAVAADVRTFSEGYIKAIEEHRDKLLQQLDDIRIQRETALQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKGVVVERLRKLNKVEYSARPGVNHKICFSPQEKAGQCQGYEVYGAINTQEVDPAQCVLQGEDLHRAREKQTASFTLFCKDASGQSMGRGGDNVHVEVVPKDKKDSPIRTVVQDNKDGSYRVSYTPKEPGIYTVWVCIREQHVQGSPFNVTVRRKHRPHPGVFHCCTFCSSGGQKAARCACGGTMPGGYLGCGHGHKGHPGRPHWSCCGKFIEKSECSFTSGQGAPRSLLRTVAL
Protein: INT (Q38184)
Organism: Lactococcus phage TP901-1
Interaction partners:
Sequence:
MTKKVAIYTRVSTTNQAEEGFSIDEQIDRLTKYAEAMGWQVSDTYTDAGFSGAKLERPAMQRLINDIENKAFDTVLVYKLDRLSRSVRDTLYLVKDVFTKNKIDFISLNESIDTSSAMGSLFLTILSAINEFERENIKERMTMGKLGRAKSGKSMMWTKTAFGYYHNRKTGILEIVPLQATIVEQIFTDYLSGISLTKLRDKLNESGHIGKDIPWSYRTLRQTLDNPVYCGYIKFKDSLFEGMHKPIIPYETYLKVQKELEERQQQTYERNNNPRPFQAKYMLSGMARCGYCGAPLKIVLGHKRKDGSRTMKYHCANRFPRKTKGITVYNDNKKCDSGTYDLSNLENTVIDNLIGFQENNDSLLKIINGNNQPILDTSSFKKQISQIDKKIQKNSDLYLNDFITMDELKDRTDSLQAEKKLLKAKISENKFNDSTDVFELVKTQLGSIPINELSYDNKKKIVNNLVSKVDVTADNVDIIFKFQLA
Protein: Cryptocephal, isoform A (Cryptocephal, isoform E) (RH01327p) (Q9VID3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Eukaryotic translation initiation factor 2-alpha kinase
- Eukaryotic translation initiation factor 2 subunit 1
- X-box-binding protein 1
- Atf6, isoform C
- GEO08928p1
- non-specific serine/threonine protein kinase
- Activating transcription factor 3
- Endoplasmic reticulum chaperone BiP
- CCAAT/enhancer-binding protein
- Asparagine synthetase
Sequence:
MDATFHQTMESLQLPKELYWDLKMEPQSPTSVLGSDLFPLTDSNDTEWLYDDNFANGITLIGDDEALTLEEVASLQLLSDEEMVVEIFDLKDEECLLDQKATLNCIDYDSNSFQPNINVITQAIVPANKVQFGASSDAASLPSAADYQLNDGPSLILQQLTPPQSPPQFDAYKQAGDAQPKPVLVKAEQKVQCYTPDVTHAASATPFNFTNWVGGSEIARENQLVDDIVNMRAKELELSTNWQQLNEDCESQASSSLDSRSTGSGVCSSIADADEDWVPELISSSSSPAPTTIEQSASQPKKRTRTYGRGVEDRKIRKKEQNKNAATRYRQKKKLEMENVLGEEHVLSKENEQLRRTLQERHNEMRYLRQLIREFYHERKR
Protein: Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) (Q9H307)
Organism: Homo sapiens (Human)
Function: Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma.
Subcellular location: Nucleus speckle. Cell junction, desmosome. Note=Cell-cell contact area, predominantly desmosome of intercellular adherens junction. Not a nucleocytoplasmic shuttling protein.
Interaction partners:
- RNA-binding protein with serine-rich domain 1
- Histone deacetylase complex subunit SAP18
- Serine/arginine repetitive matrix protein 1
- Apoptotic chromatin condensation inducer in the nucleus
- Protein mago nashi homolog
- Eukaryotic initiation factor 4A-III
- Serine/threonine-protein kinase PRP4 homolog
- Arginine/serine-rich protein PNISR
- Serine/arginine-rich splicing factor 11
- Peptidyl-prolyl cis-trans isomerase G
Sequence:
MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKTLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR
Protein: Putative zinc finger protein CONSTANS-LIKE 11 (O23379)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
Interaction partners:
Sequence:
MEARCDFCGTEKALIYCKSDSAKLCLNCDVNVHSANPLSQRHTRSLLCEKCSLQPTAVHCMNENVSLCQGCQWTASNCTGLGHRLQSLNPYSDCPSPSDFGKIWSSTLEPSVTSLVSPFSDTLLQELDDWNGSSTSVVTQTQNLKDYSSFFPMESNLPKVIEEECSGLDLCEGINLDDAPLNFNASNDIIGCSSLDNTKCYEYEDSFKEENNIGLPSLLLPTLSGNVVPNMSLSMSNLTGESNATDYQDCGISPGFLIGDSPWESNVEVSFNPKLRDEAKKRYKQKKSKRMFGKQIRYASRKARADTRKRVKGRFVKSGETFEYDPSLVM
Protein: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) (F4KH14)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEGKVFQNFNVVQSCYRQNKQFKTRYQREPDLFMSTLLPCPREKMAFNLNSSMRAHTLSKYQFVLSKQRTFYCNATSSSATVPSLDKNDFLKLQNGSDIRGVAVTGVEGEPVSLPEPVTEAIAAAFGQWLLHKKKAESRRLRVSVGHDSRISAQTLLEAVSRGLGVSGLDVVQFGLASTPAMFNSTLTEDESFLCPADGAIMITASHLPYNRNGFKFFTSDGGLGKVDIKNILERAADIYKKLSDENLRKSQRESSSITKVDYMSVYTSGLVKAVRKAAGDLEKPLEGFHIVVDAGNGAGGFFAAKVLEPLGAITSGSQFLEPDGMFPNHIPNPEDKAAMEAITKAVLDNKADLGIIFDTDVDRSAAVDSSGREFNRNRLIALLSAIVLEEHPGTTIVTDSVTSDGLTSFIEKKLGGKHHRFKRGYKNVIDEAIRLNSVGEESHLAIETSGHGALKENHWLDDGAYLMVKILNKLAAARAAGQGSGSKVLTDLVEGLEEPKVALELRLKIDKNHPDLEGSDFREYGEKVLQHVSNSIETNPNLIIAPVNYEGIRVSGFGGWFLLRLSLHDPVLPLNIEAQSEDDAVKLGLVVATTVKEFNALDTCALSNLTHSS
Protein: Autophagy-related protein 8h (Autophagy-related ubiquitin-like modifier ATG8h) (AtAPG8h) (Protein autophagy 8h) (Q8S925)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
Subcellular location: Cytoplasmic vesicle, autophagosome membrane {ECO:0000250|UniProtKB:P38182}; Lipid-anchor {ECO:0000250|UniProtKB:P38182}. Vacuole membrane {ECO:0000250|UniProtKB:P38182}; Lipid-anchor {ECO:0000250|UniProtKB:P38182}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8LEM4}.
Interaction partners:
- Protein NBR1 homolog
- Ubiquitin-like modifier-activating enzyme atg7
- Autophagy-related protein 3
- Cysteine protease ATG4b
- Cysteine protease ATG4a
- Serine/threonine-protein kinase ATG1c
- Ubiquitin-like protein ATG12A
- Autophagy-related protein 18b
- Serine/threonine-protein kinase ATG1b
- Autophagy protein 5
Sequence:
MGIVVKSFKDQFSSDERLKESNNIIAKYPDRIPVIIEKYSNADLPDMEKNKYLVPRDMTVGHFIHMLSKRMQLDPSKALFVFVHNTLPQTASRMDSLYNTFKEEDGFLYMCYSTEKTFG
Protein: Rop guanine nucleotide exchange factor 2 (AtRopGEF2) (Rho of plants guanine nucleotide exchange factor 2) (Q9LQ89)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP.
Interaction partners:
- Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein
- UDP-Glycosyltransferase superfamily protein
- Rac-like GTP-binding protein ARAC2
- Serine/threonine-protein kinase AGC1-7
- Rac-like GTP-binding protein ARAC4
- CRIB domain-containing protein RIC2
- Rac-like GTP-binding protein ARAC11
- Polyketide cyclase/dehydrase and lipid transport superfamily protein
- Alpha/beta-Hydrolases superfamily protein
- Glycosyltransferase)
Sequence:
MENLPNHEENDDVGYHQSPGPIDPNDHSASETPVYSTMSTDSFAYHRTCSETSGGGFSDQIDETSSFCTEASPSDWPVLTESNNSASSNFPTVFDLKHNQIETDEHLAVQEISEPELETMKERFSKLLLGEDMSGSGKGVCTAVTISNAITNLYATVFGQNLRLEPLEIEQKTTWKREMNCLLSVCDYIFEFIPKSQNLSNGATVEVMESRPRADIYINLPALRKLDSMLMEALDSFQKTEFWYAEEGSLSMKSTRSATGSFRKVIVQRKEEKWWLPIPLVPLQGLSEKARKQLKSKRESTNQIHKAAMAINSSILGEMDIPDSYMATLPKSGKASTGDAIYRHMTSSGRFSPEKLLDRLKIVSEHEALQLADRVEASMYTWRRKACLNNSKSSWNMVKDLMSITERSDKNYVLAERAESLLFCLKQRYPELSQTSLDICKIHCNKDVGKAVLESYSRVLEGLAFNIVAWIDDVLYVDKTMRGEE
Protein: SET domain-containing protein (Q585V9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTLLHMLGARAAPMLQARRGHDSVRGLFARRCFRKGDLLLSVPSRNCYFPHASRVPRTLRRWNRSTLFPEATMWLWRLSPDFPQDRVSLTASVSTDENEVVTLTLSPVEASLAVSIALRYFWQSVMKLKTRVGIGNPSLGPVKDRKADLYVSSLPLTEYLSYGLEAPYFSEGGCGSNVHSTIEQIAWNLRDCILLHAPQEEYRFYDAHPSELDSAILTSIYVVRARVLKLKVIRTDDVRTDTVTSAIVPIVDMLNHSASSPACAACVSLPTATVVVRAARDINVGEELTLDYGEHKGKRMFPRSHRNSFTNANELTDEEEDEDYMWESRYLFSREVAGGEHDHFE
Protein: C21orf29 protein (Q14C60)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSALLSLCFVLPLAAPGHGTQGWEPCTDLRPLDILAEVVPSDGATSGIRIVQVHGARGLQLSVAAPRTMSFPASRIFSQCDLFPEEFSIVVTLRVPNLPPKRNEYLLTVVAEESDLLLLGLRLSPAQPPCTEVEDAQFWFDASRKGLYLCVGNEWVSVLAAKERLDYVEEHQNLSTNSETLGIEVFRIPQVGLFVATANRKATSAVYKWTEEKFVSYQNIPTHQAQAWRHFTIGKKIFLAVANFEPDEKGQEFSVIYKWSHRKLKFTPYQSIATHSARDWEAFEVDGEHFLAVANHREGDNHNIDSVIYKWNPATRLFEANQTIATSGAYDWEFFSVGPYSFLVVANTFNGTSTKVHSHLYIRLLGSFQLFQSFPTFGAADWEVFQIGERIFLAVANSHSYDVEMQVQNDSYVINSVIYELNVTAQAFVKFQDILTCSALDWEFFSVGEDYFLVVANSFDGRTFSVNSIIYRWQGYEGFVAVHSLPTVGCRDWEAFSTTAGAYLIYSSAKEPLSRVLRLRTR
Protein: 5'-3' exoribonuclease 1 (EC 3.1.13.-) (E1JJR3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR006743}.
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm1
- Decapping protein 1, isoform A
- Regulator of nonsense transcripts 1 homolog
- Enhancer of mRNA-decapping protein 3
- Protein associated with topo II related - 1, isoform A
- m7GpppN-mRNA hydrolase
- 5'-3' exoribonuclease 2 homolog
- LD23303p
- Eukaryotic translation initiation factor 4E1
- ATP-dependent RNA helicase me31b
Sequence:
MGVPKFFRYISERYPCLSELAREHCIPEFDNLYLDMNGIVHNCSHPDDNNIHFHLEEEQIFQEIFNYVDKLFYLIKPQRLFFLSVDGVAPRAKMNQQRSRRFRTAREAEQQEAKAAQRGELREHERFDSNCITPGTEFMVRLQEGLRAFLKTKISTDPLWQRCTVILSGQEAPGEGEHKIMDYIRYMKTQPDYDPNTRHCLYGLDADLIILGLCTHELHFVVLREEVKFGRNVKRTSVEETRFFLLHLGLLREYLELEFDALRTDEHKLDIAQLIDDWVLMGFLVGNDFIPHLPCLHISSNALPLLYRTYIGIYPTLGGNINENGKLNLRRLQIFISALTEVELDHFKEHADDLKYMNNKSEAFDMDVGEITESQNLDSDLGALINKSMLLYDDDSEEDCSDENAVLLKEFQNYKRNFYRNKFKRDPNDELIEELCHHYVNALQWVLDYYYRGVQSWDWYYPFHYTPFISDLKNIEQVEIAFHMGTPFLPFQQLLAVLPAASAKLLPVAYHDLMLLPTSPLAEFYPLEFESDLNGKKHDWEAVVLIPFIDEGRLLAAMLPCEAQLSLEERERNRHGPMYVYKYSTVAQGPMPAYPPLRALPVLYCTEVAKWSHEIAVNLPYSVCIELPNAARTVFFPGFPTMQHLPFDFELRNDRVKVFEQVSRNQNIVLKPRKRQLEDTLTAVASQYLGKVIHVGWPHLVKAIVVRVATRDQRVDSEGITLNDSRRFDSECKALQEHFINRMGIQFANYDVLVYVRTFAGNSTEFRDKGALMVRDSWSSSVTGYPAQGVVADLTVWERMRKNFLNVEHYFPVGSTIFLITDPYYGSEGTVQDPRLAYTNGRIQVSIMVRPEPKVNAARQLQEERDRDYLSTFQVCNLLRISGRTLGRLSGTVWVVLGPRRQKMENVTKHNIGLQLKYPRQNEERAGYCFRTNNQWYYSSLAVDLMRNYCQRYPDVIDFFGDSNDRAEFVFEQDVFPNAVGHRRVEELANWVRQQPHMKVERISCGSKTVCRETIELLIAAVDDLRSLPVKHVKLQVKPHLLIKPNVTLPDVYRSKRPVRLFDRVVIVRTIYMVPVGTKGTVIGIHPVTDPNPVRLECVHAVDTFCKVLFDSPVPNCNNIHGIAEDRVYKVPEIALVIIKTDEEGKKQNDCELPVRDPQPNQAQDEPVRATSSRYVTAAGSTSVPITMKTQISDEFVKTRSDPIARTDSYKPSSEPKPVPVPEQITNWRERVSTPTNKPQPAPNNWRINRSSSRQQGGSIFVAPPTKTPDAAASTASTAFTAASSATLTPLDQTLALMSVLGVGEDQSSPPLQEAVQQQRPPLLQQQRAPFPGQMPNLPKPPLFWQQEAQKQEALQQEAQQQEAQKKQQQAHAQMEPERINSQHFYRSGQTGAALNQPPLGAPSKRQWHEWVHPRMQHANAFHAGVNNGYQMRPKKNIAAQSTFNNNVHMHLQQPYYPNQQQQQQQQQPLQLTEINNAPPRYSTIQDFVPIQAYRPKKLNRVQPAGRQDVDATKNPSRSPVLQQPTNETIDTKASSSLPVQSAGEQVIGLMQTLEIKQPAASQSESDGVSTGSANAPTATTSSQAVNRRKHRVPRIGAKFDLEYILPDSPHPT
Protein: Serine carboxypeptidase-like 50 (EC 3.4.16.-) (Q9M9Q6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable carboxypeptidase.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Phosphoglycerate mutase-like protein 1
- Subtilisin-like protease SBT1.6
- Subtilisin-like protease SBT2.5
- Prolyl endopeptidase
- Prolyl endopeptidase
- Proteasome activator subunit 4
- ATP-dependent zinc metalloprotease FTSH 3, mitochondrial
- Lon protease homolog 1, mitochondrial
Sequence:
MEQATTLFILLSTLLLAVSVESPQPPLFPDEALPTKSGYLPVKPAPGSSMFYAFYEAQEPTTPLPDTPLLVWLQGGPGCSSMIGNFYELGPWRVVSRATDLERNPGAWNRLFGLLFVDNPIGVGFSIAASQQDIPTNQRQVAEHLYAALVEFLEQNPSFENRPVYFTGESYAGKYVPAIGYYILKEKPNGKVNLKGLAIGNGLTDPVTQVQTHAVNVYYSGLVNAKQRVELQKAQEISVALVKSQKWREAADARTELLTLLSNMTGLATLYNTARAIPYRTDLVVDLLNQREAKRVLGVSETVRFEECSDEVEDVLRADVMKSVKFMVEYALERTQVLLYQGMLDLRDGVVSTEEWMKTMNWSGLGMFSTAERRVWKDEDGVVAGYVQRWGNLCHVAVTGAGHFVPTDKAVNSRDMIEGWVLGKGLFGGKDVKQTTSSSLYHSI
Protein: Protein smoothened (Q5RH73)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P56726}; Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium {ECO:0000250|UniProtKB:P56726}. Note=Cilium localization is promoted by shh and is required for activity. {ECO:0000250|UniProtKB:P56726}.
Interaction partners:
- Protein patched homolog 1
- Protein patched homolog 1
- Sonic hedgehog protein
- GLI family zinc finger 2a.
- Tiggy-winkle hedgehog protein
- Indian hedgehog B protein
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase
Sequence:
MSSKRPCSIVGSFWMLWIWTATSMVARAVILHPNETIFNDFCKKSTTCEVLKYNTCLGSPLPYTHTSLILAEDSETQEEAFEKLAMWSGLRNAPRCWAVIQPLLCAVYMPKCENGKVELPSQHLCQATRNPCSIVERERGWPNFLKCENKEQFPKGCQNEVQKLKFNTSGQCEAPLVKTDIQASWYKDVEGCGIQCDNPLFTEDEHSDMHSYIAVFGTITLLCTFFTLATFLADWKNSNRYPAVILFYVNACFFIGSIGWLAQFMDGARNEIVCKSDNTMRLGEPSSTETLSCVIIFVIVYYSLMSGVIWFVMLTYAWHTSFKALGTTHQPLSGKTSYFHLVTWSIPFILTVAILANSQVDADSVSGICFVGYRYYEYRAGFVLAPIGFVLVIGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFGCHFYDFFNQAEWERSFREYVLCEANVTIAHQTNKPIPECAIKNRPSLLVGKINLFSMFGTGIAMSTWVWTKATILIWKRTWFRIIGRSDDEPKRIKKSKMIAKAFSKRKELQKDPEKELSFSMHTVSHEGPVAGINFDLNEPSIEMSSAWAQHVTKMVARRGAILPQDISVTPTGTPIPPPEERNKLWMVEAEISPEMMKRKKKKKKRRKEVRPAGPAADEGNPAYHRREFGPSAVPRLPKLPGHRSLVANLWEQQRQQQEEQDMLPGAFPEFRPSCPLPYQDRYGGLGYLRNKPSSLPLANPLTLRDSMQGDLSHFQQSSWQPKGVFRHLGQEASMMDVGRTAVVPRADGRRGVQIHSRTNLMDAELLDADSDF
Protein: GIMAP1-GIMAP5 readthrough (A0A087WTJ2)
Organism: Homo sapiens (Human)
Interaction partners:
- GTPase IMAP family member 5
- GTPase IMAP family member 6
Sequence:
MGGRKMATDEENVYGLEENAQSRQESTRRLILVGRTGAGKSATGNSILGQRRFFSRLGATSVTRACTTGSRRWDKCHVEVVDTPDIFSSQVSKTDPGCEERGHCYLLSAPGPHALLLVTQLGRFTAQDQQAVRQLSHGAFSPSTWLLLNCVCSTSLSPVNSIPAHRRRAGLSLLPLHLPERGPAARASVTATLEDRAQQPFLERMGGFQRGKYGTMAEGRSEDNLSATPPALRIILVGKTGCGKSATGNSILGQPVFESKLRAQSVTRTCQVKTGTWNGRKVLVVDTPSIFESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGRFTAQDTVAIRKVKEVFGTGAMRHVVILFTHKEDLGGQALDDYVANTDNCSLKDLVRECERRYCAFNNWGSVEEQRQQQAELLAVIERLGREREGSFHSNDLFLDAQLLQRTGAGACQEDYRQYQAKVEWQVEKHKQELRENESNWAYKALLRVKHLMLLHYEIFVFLLLCSILFFIIFLFIFHYI
Protein: UDP-glucose 4-epimerase (EC 5.1.3.2) (UDP-galactose 4-epimerase) (Uridine diphosphate galactose 4-epimerase) (P9WN67)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
Interaction partners:
- Possible dTDP-glucose 4,6-dehydratase
- UDP-glucose 6-dehydrogenase
- UDP-galactopyranose mutase
- UTP--glucose-1-phosphate uridylyltransferase
- Uncharacterized protein Rv0501
- Possible transferase
- Galactose-1-phosphate uridylyltransferase
- HNH nuclease domain-containing protein
- Possible conserved membrane protein
- Small ribosomal subunit protein uS19
Sequence:
MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNIGTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGVRRTVEYFRHKHTD