wanglab/gogpt-training-data huggingface dataset:
Protein: Triple functional domain protein (H2KYM4)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MRRSQTVEGSTDSEGGGGTTPTKSSKKERWSFAIKRRWFSSSTSRHSHDHDVAIVQPTKTTLGGTDNNNAESGSVPDRPDDSNASGSTVSKRKSLRRIFANSSKERAAAANSSSSNNNSPATRQSTSTSSPVTANGHTTESSTSAPIGVLSSGEPTSSNSIPSSSTPTHTVPSSVPATVIPIVVAEDEKAEDCLPPPMENITINNSIDEKDMNEDSVAASDAVEPEVALPAKVEKTPEETARFKRSYVLMELVETEQDYVKDLTSVVEGYIGNLNKMDLPADLVGKDKIIFANIVNILEFHKTNFLKEIEKCSENYEAAGAAFVKYERRLHTLYVTYCQNKPKSDYLLAQDDFEAFFADTKAKLGHKVALCDLLIKPVQRIMKYQLLLKDILKFTERAKDKTDTLKKALQVMHVVPKACDDMMQVGRLQNFDKSLSAQGKLIHQGTLQISESIAGNVQKPKDRRIFLFEQSAIIADHIPPKKEFGNPTYIFKSQFMVNKMVFEPNVPDDPLRFVIKSSDPTQPTSFIANAQSQEEKDEWNRKMSELLDQQKRLLAALVDPRRYNDMSSGMGDLSLGAPGGDRRGAPSSANRSAASSSKKPAESPKKEGKSKSSLFSFGKKPAKSPTSPPPLDAAAAGKFQKVADDQVNLETDEKVKVLDVKNGYASVKKADGTVGKCPSYFLTMSDIPGTNFAEQIQYRREWQRRVDETDVEYGPSAFDTATSSTDNFDVLLELTTCERPVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQTNQLNSRLLIKHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEVRLKWKAESGLKYCIEYRILDDSSPENWLIASTNIEKTHVSLRNFARNSYSFRVFAYNQRVRSAPSQCICICFDGTEM
Protein: Protein MxiC (Q04640)
Organism: Shigella flexneri
Function: Necessary for the secretion of IPA invasins.
Subcellular location: Secreted {ECO:0000269|PubMed:11115111}. Host cell {ECO:0000305|PubMed:11115111}. Note=Secreted via Mxi-Spa type III secretion system (T3SS), and delivered into the host cytoplasm. {ECO:0000305}.
Interaction partners:
Sequence:
MLDVKNTGVFSSAFIDRLNAMTNSDDGDETADAELDSGLANSKYIDSSDEMASALSSFINRRDLEKLKGTNSDSQERILDGEEDEINHKIFDLKRTLKDNLPLDRDFIDRLKRYFKDPSDQVLALRELLNEKDLTAEQVELLTKIINEIISGSEKSVNAGINSAIQAKLFGNKMKLEPQLLRACYRGFIMGNISTTDQYIEWLGNFGFNHRHTIVNFVEQSLIVDMDSEKPSCNAYEFGFVLSKLIAIKMIRTSDVIFMKKLESSSLLKDGSLSAEQLLLTLLYIFQYPSESEQILTSVIEVSRASHEDSVVYQTYLSSVNESPHDIFKSESEREIAINILRELVTSAYKKELSR
Protein: Glucan 1,3-beta-glucosidase 2 (EC 3.2.1.58) (Exo-1,3-beta-glucanase 2) (Q5AIA1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. EXG2 is not heavily involved in the exoglucanase function of the adhesion process.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
Interaction partners:
- glucan 1,3-beta-glucosidase
- 1,3-beta-glucan synthase
- Glucan 1,3-beta-glucosidase
- beta-glucosidase
- beta-glucosidase
- 1,3-beta-glucan synthase
- 1,3-beta-glucan synthase
- Glucan 1,3-beta-glucosidase BGL2
- Glucoamylase 1
- Glucoamylase 1
Sequence:
MMLFLIHLMALCCMFVAEVACEQFNSTSNSSSAQSSLIDFQYKGVSIGGWLVLEPYITPSLFNATLSSGETWTDLPVDEYHFCEKLGAKEAEKRLTDHWESMYNETDFKQIKEAGLNMVRIPIGYWSFEKLEGDPYVSGAQDYLDKAIEWSHANDLKVMIDLHGAPNTQNGFDNSGLRNLGYPGWQNKTEYVNHTYKVLQQMFQKYGTGKYASDYKNTIIGIEVLNEPLNPNMDKLKEFYIESYNDGREIQVINNTIFFQEAFQPIGYWDSFLEKGEIKVTETSNGTNHTTTKKADFKNIIIDHHHYEVFTESQVASNVSTHLENIKNYASAIGKEKAKAIVGEWSAALTDCAPWLNGVGLGSRYEGTAPYTNDRVGSCAEFNKSPDKWSKKQKKDYRRFVEMQLYEYSTNSQGWIFWCWKTEGATEWDFRALVKNGIMPQPLDNYKYVKNGTDTSSASAIASNKMTLLLAFLLVILVI
Protein: Sodium-dependent dopamine transporter (Protein fumin) (Q7K4Y6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Sodium-dependent dopamine transporter which terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. Also transports tyramine and norepinephrine, shows less efficient transport of octopamine and does not transport serotonin. Plays a role in the regulation of the rest/activity cycle.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24037379, ECO:0000269|PubMed:25970245}; Multi-pass membrane protein {ECO:0000269|PubMed:24037379, ECO:0000269|PubMed:25970245}.
Interaction partners:
Sequence:
MSPTGHISKSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQSMAMVLNGVTTEVTVVRLTDTETAKEPVDV
Protein: Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3) (OCT3) (O75751)
Organism: Homo sapiens (Human)
Function: Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. Mediates the transport of polyamine spermidine and might be involved in its disposition (By similarity). Transports dopaminergic neuromodulators cyclo(his-pro) and salsolinol with lower efficency. May contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (Probable).
Subcellular location: Cell membrane {ECO:0000269|PubMed:15817714, ECO:0000269|PubMed:20858707}; Multi-pass membrane protein {ECO:0000305}. Apical cell membrane {ECO:0000269|PubMed:15817714, ECO:0000269|PubMed:16263091}; Multi-pass membrane protein {ECO:0000305}. Basolateral cell membrane {ECO:0000269|PubMed:15817714}; Multi-pass membrane protein {ECO:0000305}. Mitochondrion membrane {ECO:0000250|UniProtKB:O88446}. Endomembrane system {ECO:0000250|UniProtKB:O88446}. Nucleus membrane {ECO:0000250|UniProtKB:O88446}. Nucleus outer membrane {ECO:0000250|UniProtKB:O88446}. Note=Localized to the apical/brush border membrane of enterocytes (PubMed:16263091). Localized to the luminal/apical membrane of ciliated epithelial cells in bronchi (PubMed:15817714). Localized to the basolateral membrane of intermediate cells in bronchi (PubMed:15817714). Localized to the entire plasma membrane of basal cells in bronchi (PubMed:15817714). {ECO:0000269|PubMed:15817714, ECO:0000269|PubMed:16263091}.
Interaction partners:
- Cation-independent mannose-6-phosphate receptor
- Sodium-dependent noradrenaline transporter
- Histone-lysine N-methyltransferase EHMT2
- Equilibrative nucleoside transporter 4
- Multidrug and toxin extrusion protein 1
- Sodium-dependent serotonin transporter
Sequence:
MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHSCKCGRNKKTPVSRSHL
Protein: PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma) (Q9Z1Z9)
Organism: Rattus norvegicus (Rat)
Function: May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19900557}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). {ECO:0000250}.
Interaction partners:
Sequence:
MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRAQPAQSKPQKALTPPADPPRYTFAPSASLNKTARPFGAPPPTDSALSQNGQLLRQLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEFMKKSSQVPRTEAPAPASTIPQESWPGPTTPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQNRTSIVQAAAGGGTGGGSNNGKTPVCHQCHKIIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPSCYDVRYAPSCAKCKKKITGEIMHALKMTWHVPCFTCAACKTPIRNRAFYMEEGAPYCERDYEKMFGTKCRGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDKPLCKSHAFSHV
Protein: Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (OTU domain-containing protein 1) (P43558)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Participates in the regulation of the ubiquitin conjugation pathway involving CDC48 by hindering multiubiquitination of substrates at the CDC48 chaperone. May be indirectly involved in PIS1 gene expression.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Cell division control protein 48
- Ubiquitin fusion degradation protein 1
- Protein DOA1
- Nuclear protein localization protein 4
- E4 ubiquitin-protein ligase UFD2
- UBX domain-containing protein 1
- Polyubiquitin
- Protein SPT23
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-ribosomal protein eL40A fusion protein
Sequence:
MKLKVTGAGINQVVTLKQDATLNDLIEHINVDVKTMRFGYPPQRINLQGEDASLGQTQLDELGINSGEKITIESSDSNESFSLPPPQPKPKRVLKSTEMSIGGSGENVLSVHPVLDDNSCLFHAIAYGIFKQDSVRDLREMVSKEVLNNPVKFNDAILDKPNKDYAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNEDKFDNYILILFNGIHYDSLTMNEFKTVFNKNQPESDDVLTAALQLASNLKQTGYSFNTHKAQIKCNTCQMTFVGEREVARHAESTGHVDFGQNR
Protein: Ras-related protein R-Ras2 (EC 3.6.5.-) (Ras-like protein TC21) (Teratocarcinoma oncogene) (P62070)
Organism: Homo sapiens (Human)
Function: GTP-binding protein with GTPase activity involved in the regulation of MAPK signaling pathway, thereby controlling multiple cellular processes. Involved in the regulation of MAPK signaling pathway. Regulation of craniofacial development.
Subcellular location: Cell membrane {ECO:0000269|PubMed:28406396, ECO:0000269|PubMed:31130282}; Lipid-anchor {ECO:0000269|PubMed:15308774, ECO:0000269|PubMed:28406396}; Cytoplasmic side. Golgi apparatus membrane {ECO:0000269|PubMed:31130282}; Lipid-anchor {ECO:0000269|PubMed:15308774}.
Interaction partners:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- RAF proto-oncogene serine/threonine-protein kinase
- Ras and Rab interactor 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- Ral guanine nucleotide dissociation stimulator
- Serine/threonine-protein kinase A-Raf
- Neurofibromin
- Afadin
- Serine/threonine-protein kinase B-raf
Sequence:
MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF
Protein: Nuclear hormone receptor family member nhr-60 (O17898)
Organism: Caenorhabditis elegans
Function: Orphan nuclear receptor (Potential). Required for embryonic and larval morphogenesis and probably for seam cell positioning and migration.
Subcellular location: Nucleus {ECO:0000269|PubMed:17579999}. Note=Localized in the nucleus from the one-cell stage of development onwards. Localizes to the nuclear periphery of all cells. {ECO:0000269|PubMed:17579999}.
Interaction partners:
- Nuclear receptor corepressor 1
- MADF domain-containing protein
Sequence:
MIQSSSSISQDSLDLPSILSTFSADEPEDEPSPTAVKSTKPQRPTECLICGNSANGHHYDVASCNGCKTFFRRMCVSDRSFECKAKGDCFDLTKRKVPLKCRACRHQKCISVGMNPLAMEVDEKAASSSNFKKLVKRAQDLEPDDDCQVTAVVNKMQIVKPVDSIESKMQNITDMLVYLETKVERFRKSAYNPHWNEFSGLEYLLESECRIGFGDRFGPMPGWPLRRDQLGPPRLPKPPSPGKPRDSQHSQNIKQWFFYNLLTTVEYAKTFMFFHRLSSRDKLILTRHVALACTNLHISYSSIRRNLEVIIEPDGSEPMTFNDTHYSASVMSVAPLIRCQIKNIEYLLLKAIVLCNPAVPDLSAKSQEIISLERVKYADALFNYCLRSRSDGPPHFAQLIQIIDVLERQQRMQKDLHLLLVAPKVAKLPKDLVMRVIEDIMDS
Protein: 65 kDa invariant surface glycoprotein (Q587F3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMKYLLVFAIIATRIPVLLATNGGDKHVKANKKLTKEGAAALCKMKHLADKVAEERSQELKDRTQNFAGYIEFELYRIDYWLEKLNGPKGRKDGYAKLSDSDIEKVKEIFNKAKDGIAKQLPEAKKAGEEAEKLHTEVKKAAKNARGVRLSEGTNSSGLYRILDWYCFKEGENAGKSDNCDGVKFSVHYETHRRRNVIDCSSTGYEENYDWSANALQVALNSWENVKPKKVESAGSDMNCNIGQSSESHPCTMTEEWQTPYKETVEKLRELEDAYQRGKKAHDAMLGYANTAYAVNTKVEQEKPLTEVIAAAKDAGKKGAKIIIPAAAPATPTNSTKNEDSASTEHVDRGIATNETQVEVGIDADFDSLLDATEAAEVTRRHQRTAMIILAVLVPAIILVVTAVAFFIMVKRRRNSSKDVDTGKAEGGVSSVKVVM
Protein: Protein disconnected (P23792)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for the establishment of stable connections between the larval optic nerves, the Bolwig's nerves, and their target cells in the brain during embryonic development.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Uncharacterized protein, isoform C
- AT27166p
- DISCO interacting protein 1, isoform D
Sequence:
MEHIMNPFMSPAYLLGHGPHSHQHVHSHLPSHPQPNAASPASSPGGSSGSGSGSAAGSGTGSGSSLKPRRWGSPPINLAGQFINPATGKKRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSSRRSRNRHSANPNPKLHSPHIRRKISPHDGRTAQQFPVFSPGTAAAAAAVAGRLPVAFPGLLPPPPPHHGHHPYVMFGGQAGLHGLGLLSTGCQDPDSGSVDNEQDADPEDDNDFVYVDMQANSSSPAASSEDQEEHERDNEQDEEMHCSLSLASSSSIAADEERAADQPLDFSLHKRRKSEQDREQEQEQEQEREREAEKEQEQDVESDKEHEPEQEHELEREKRSPSDAFSMDQLLGKRKRHDSTASSSACSTAAASSASSSSASASANPPQTSIKMDLDPDSDSAYMTSRRQMLPLPVLDLEEHHHLRLLQTQMFAAAAAAAATSQAPPTAFLPAGSPVDLAKDSPPMWSLLSEMYRSMLLKTQHQQYNHHHQLQQQHQQEQHHHLTLSHHHQEQHHHLGHHHMGHHHHHHHQHHQQQPQQQSPAATNAPISV
Protein: RAB6B, member RAS oncogene family (A0A0G2JT78)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Rab GDP dissociation inhibitor beta
- GRIP and coiled-coil domain-containing protein 2
- Rab GDP dissociation inhibitor alpha
- ADP-ribosylation factor-like protein 1
- Guanine nucleotide exchange factor subunit RIC1
- BICD cargo adaptor 2)
- VPS39 subunit of HOPS complex
- BICD cargo adaptor 1
- Vacuolar protein sorting-associated protein 52 homolog
- Vacuolar protein sorting-associated protein 53 homolog
Sequence:
MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC
Protein: snRNA-activating protein complex subunit 3 (Small nuclear RNA-activating complex polypeptide 3) (Q5T282)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAEGSRGGPTCSGVGGRQDPVSGSGGCNFPEYELPELNTRAFHVGAFGELWRGRLRGAGDLSLREPPASALPGSQAADSDREDAAVARDLDCSLEAAAELRAVCGLDKLKCLEDGEDPEVIPENTDLVTLGVRKRFLEHREETITIDRACRQETFVYEMESHAIGKKPENSADMIEEGELILSVNILYPVIFHKDLYKSAFFYFEGTFYNDKRYPECRDLSRTIIEWSESHDRGYGKFQTARM
Protein: Probable protein kinase UbiB (EC 2.7.-.-) (Ubiquinone biosynthesis protein UbiB) (P0A6A0)
Organism: Escherichia coli (strain K12)
Function: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00414, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00414, ECO:0000269|PubMed:15919996}.
Interaction partners:
- Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
- Ubiquinone biosynthesis accessory factor UbiJ
- 4-hydroxybenzoate octaprenyltransferase
- Ubiquinone biosynthesis O-methyltransferase
- Sec-independent protein translocase protein TatC
- Sec-independent protein translocase protein TatB
- Sec-independent protein translocase protein TatA
- 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
- 3-demethoxyubiquinol 3-hydroxylase
Sequence:
MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDGKLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGATLVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR
Protein: Protocadherin alpha-10 (PCDH-alpha-10) (Q91Y20)
Organism: Mus musculus (Mouse)
Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular location: Cell membrane {ECO:0000303|PubMed:11230163}; Single-pass type I membrane protein {ECO:0000303|PubMed:11230163}.
Interaction partners:
Sequence:
MSCVAMKYCHESWCLLLSLLLFAIWEPGSGQLRYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPVFPTTEKNLFVSESRALDPHFSLEGASDADIGTNALLTYRLSPSEYFSLEVPTTDELVKPLQLVLKKPLDRERASELHLVVKATDGGKPELTGTLELHITVLDANDNAPAFDRAIYRVKLVENARNGTVVIRLNASDLDEGSNGQILYSFAADVSPKTEATFHIDSVSGEIKVNGKIDFEETNLWKIQAEAVDKGSPPMFGHCTILIEVLDINDNAPKIIVTSLSLPVQEDAPVGTVIALISVMDPDSTVNGQVTCSLSPHVPFKLVSTFKNYYSLVLDSALDRETTADYKVVVTARDGGSPALWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGVHVFTVLAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVTAKDAGVPALGSNVTLQVFVLDENDNAPTLLPHGAVGAGGAVSELVPRSVGSGHVVAKVRAVDADSGYNAWLSYELQFRAGSVRSPFRVGLYTGEISITRALDEADAPRQRLLVLVKDHGEPALTATATVLVSLVESNQAPKASSRVLGPAASESSVVDVNVYLIIAICAVSSLLVLTLVLYTALRCSALPTEVTCGPGKPMLVCSSAVGSWSYSQQRRQRVCSGEGPPKTDLMAFSPSVPPGLGSGDSGVQQEIFENPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Protein: Small ribosomal subunit protein eS21 (40S ribosomal protein S21) (Overgrown hematopoietic organs at 23B) (O76927)
Organism: Drosophila melanogaster (Fruit fly)
Function: May be an associated component of the ribosome rather than a core structural subunit. May act as a translation initiation factor. Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P63220}. Cytoplasm {ECO:0000269|PubMed:10022917, ECO:0000305|PubMed:23636399}. Rough endoplasmic reticulum {ECO:0000250|UniProtKB:P63221}. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity). {ECO:0000250|UniProtKB:P63220, ECO:0000250|UniProtKB:P63221}.
Interaction partners:
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS26
- Large ribosomal subunit protein uL29
- Large ribosomal subunit protein eL39
- Small ribosomal subunit protein eS10B
- FI01658p
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein eS4
- Large ribosomal subunit protein uL22
Sequence:
MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGIITKNF
Protein: Serine/arginine-rich splicing factor SC35 (At-SC35) (AtSC35) (SC35-like splicing factor) (Q9FMG4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably involved in intron recognition and spliceosome assembly, but not involved in alternative splicing regulation of the SCL33 intron.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:15133128}.
Interaction partners:
- Serine/arginine-rich splicing factor RS2Z33
- Serine/arginine-rich-splicing factor SR34
- Serine/arginine-rich SC35-like splicing factor SCL30
- Serine/arginine-rich SC35-like splicing factor SCL30A
- Serine/arginine-rich SC35-like splicing factor SCL28
- Serine/arginine-rich splicing factor RSZ21
- Serine/arginine-rich splicing factor RSZ22
- Serine/arginine-rich splicing factor RSZ22A
- Serine/arginine-rich splicing factor SR34B
- Serine/arginine-rich splicing factor RS31
Sequence:
MSHFGRSGPPDISDTYSLLVLNITFRTTADDLYPLFAKYGKVVDVFIPRDRRTGDSRGFAFVRYKYKDEAHKAVERLDGRVVDGREITVQFAKYGPNAEKISKGRVVEPPPKSRRSRSRSPRRSRSPRRSRSPPRRRSPRRSRSPRRRSRDDYREKDYRKRSRSRSYDRRERHEEKDRDHRRRTRSRSASPDEKRRVRGRYDNESRSHSRSLSASPARRSPRSSSPQKTSPAREVSPDKRSNERSPSPRRSLSPRSPALQKASPSKEMSPERRSNERSPSPGSPAPLRKVDAASRSQSPYAAE
Protein: Chromatin-remodeling complex subunit IES6 (Ino eighty subunit 6) (P32617)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Also involved in the regulation of telomere length.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- RuvB-like protein 1
- Actin-related protein 5
- RuvB-like protein 2
- Actin-like protein ARP8
- Ino eighty subunit 3
- Ino eighty subunit 5
- Ino eighty subunit 2
- Actin-related protein 4
- Ino eighty subunit 4
- Non-histone protein 10
Sequence:
MSGSRGNSSNSSVSNNSNNNNNNDGGDERLLFLRSVGERNEIGFPSRFKSAHYKKPTRRHKSARQLISDENKRINALLTKANKAAESSTAARRLVPKATYFSVEAPPSIRPAKKYCDVTGLKGFYKSPTNNIRYHNAEIYQLIVKPMAPGVDQEYLKLRGANFVLK
Protein: Histone H2A (Q57YA3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU003767}.
Interaction partners:
- FACT complex subunit
- Polyubiquitin, putative
- Histone H2A
- Histone H4
- Histone H4
- SET domain-containing protein
- Histone H3, putative
- DNA-directed RNA polymerase subunit beta
- Histone H3 variant
- Plastid-encoded RNA polymerase subunit alpha
Sequence:
MATPKQAVKKASKGGSSRSVKAGLIFPVGRVGTLLRRGQYARRIGASGAVYMAAVLEYLTAELLELSVKAAAQQTKKTKRLTPRTVTLAVRHDDDLGALLRNVTMSRGGVMPSLNKALAKKQKSGKHAKATPSV
Protein: Ubiquinol-cytochrome-c reductase complex assembly factor 6 (Protein brawnin) (E7EXZ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation. Mediates early complex III biogenesis. Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (By similarity). Also required for cytochrome c oxidase complex (complex IV) assembly (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:32161263}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q69YU5}.
Interaction partners:
Sequence:
MPAGVSWPRYLRMFAASVLSMFAGAQVVHHYYRPDLSIPEIPPKPGELRTELLGLKERQMDSQKQ
Protein: B-cell receptor-associated protein (BCR-associated protein) (Q6AY58)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367026}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367026}.
Interaction partners:
- Mitochondrial fission 1 protein
- Caspase-8
- Phosphofurin acidic cluster sorting protein 2
- Vesicle-associated membrane protein-associated protein B
- Calnexin
- Dynamin-1-like protein
- Mitochondrial import receptor subunit TOM40 homolog
- Mitofusin-2
- PDZ domain-containing protein 8
Sequence:
MSLQWTAVATFLYAEVFAVLLLCIPFISPKRWQKIFKSRLVELVVTYGNTFFVVLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGTAEDGGKLDVGSPEMKLEENKILKTDLKKLKDELASTKKKLEKAENEALAMQKQSEGLTKEYDRLLEEHAKLQASVRGPSDKKEE