wanglab/gogpt-training-data huggingface dataset:
Protein: 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Q8K3A9)
Organism: Mus musculus (Mouse)
Function: S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA), leading to stabilize it (By similarity). Also has a non-enzymatic function as part of the 7SK RNP complex: the 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb) in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC) (By similarity). In the 7SK RNP complex, MEPCE is required to stabilize 7SK RNA and facilitate the assembly of 7SK RNP complex (By similarity). MEPCE has a non-enzymatic function in the 7SK RNP complex; it has a non-enzymatic function; interaction with LARP7 within the 7SK RNP complex occluding its catalytic center (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q7L2J0}.
Interaction partners:
- Protein HEXIM1
- La-related protein 7
- Protein HEXIM2
- Cyclin-dependent kinase 9
- Cyclin-T1
- La ribonucleoprotein 7, transcriptional regulator, pseudogene
- Spliceosome associated factor 3, U4/U6 recycling protein
- Bromodomain-containing protein 4
- Cyclin-T2
Sequence:
MIEMAAEKEPFLVPAPPPPLKDESGGGGGPEVQSHQEAASGELRDGTEHGPGPRAHSAGAAASGGGGPQAQAHGEPHGRAAAPADVGEERRGGGGTDLGPPAPPRPRNGYQPHRPPGGGGGKRRNSCNVGGGSGGSFKHPAFKRRRRVNSDCDSVLPSNFLLGGNIFDPLNLNSLLDEEVSRALNAETPKSSPLPAKGRDPVEILIPKDITDPLSLNTCTDEAHVVLASPLKIGRKRHRHRGPHHQQQQQASGGNDSNAAVLPTDPLTPSLHGEGATQQQQNRGQNRDAPQPYELNTAINCRDEVVSPLPSALQGSSGSLSAPPAASVTSAPSTSSSSRHRKRRRTSSKSEAGARGGSQGSKEKGRGSGGGRHHHHPLPATGFKKQQLKFQYGNYCKYYGYRNPSCEDVRLRVLKPEWFQGRDVLDLGCNVGHLTLSIACKWGPARMVGLDIDPRLIHSARQNIRHYLSEELRLQAQTSEGDPGTEGEEGTITVRKRSCFPASLTASRGPIAAPQVPLDGADTSVFPNNVVFVTGNYVLDRDELVDAQRPEYDVVLCFSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYCKRKSLTETIYKNYFRIQLKPEQFSSYLTSPEVGFSSYELVATPNNTSRGFQRPVYLFHKARSPSH
Protein: ATP-dependent DEAD/H RNA helicase, putative (Q57VA7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA-binding protein, putative
- Pescadillo homolog
- RNA-binding protein, putative
- Nucleolar protein, putative
- Peter pan protein, putative
- NLE domain-containing protein
- U3 small nucleolar RNA-associated protein 14
- Ribosome biogenesis protein BOP1 homolog
- Ribosome production factor 2 homolog
- Nucleolar complex protein 2
Sequence:
MPPTPLRRRATSAEPRRGSLRCGNTAATSSRRIGVRSGKSSQGNDLTAPSVATEVMLEDTPSFFQGITGVRSVPMSHQLSGDQDYAQLMPGETISTGGNSHKRSGQQTQDKVMWIELGLCKALVRAISHIGYISPTPVQAQAIPAILSGTDVCARAVTGSGKTAAFLLPLLHLLLTRAPMKQTRMNSKRRYIRAIVLVPTRELGMQCQQVLQQFLAFTTGLQVSLAIGGVSPSAQLAALEACPDILVATPGRLVDLIHNHKGAQSAVDITGVEVVVLDECDKMLTVVLRDQVVDILKRVPEETRQVLMFSATMTTEVDEFAKEHLFKPKNVDIGHVALQAKLRQQFVRVRLHADTSLQPTEENRGDVAPSAEGCQKKTRSKRSHDKPQSEGRQNHSEESESEAEHMTKVKSRYLVALCTGYFREKTLIFTRYRTTAHRLRLLFNVIGFPSVELQGNQLQEERFASLEKFASGEVNYLFSTDVASRGLDIKDVSTVINFDLPPTLTAYIHRVGRTARIGGSGTAVSLVDESRDSDIMRKILAVSGVVSNHQAATVRRRDVPEELLQEAIKKIDAAFPQVRAELAAEELHTKIERAERRYGREAGEKILTESAAVRPRRVWCLSHTEQKKREEEARRVYETEAEVTVNQFQQELANWDREENKFLKKQRNERRAQRETKARANERAKNAARELQRKSQNKLQAGIVKKLKKKKIRDARKTRRAESREKNGKPAYKHRGGVKSMKKSRHKRRMSRH
Protein: Paired-like homeodomain containing protein (O54817)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MENSLFNSMFLEEANYQEPEGFEPSRGEAAAPVAEAPQAWNGNENLGGGFLEANAQLGEADAAPVRQSLMRPLMQPVAQSSPQPLPANPLQAPQQPEEQEEEEEEQPGEEQPQQEPKPRRYRICFTPIQLQELEAFFQRVQYPDLFARVELARRLGLPEPRVQVWFQNRRAKWRRLRRAQAFRNMVPVAMSPPVGVYLDDHYGPIPIVEVIWKCYPMVPRPMHPQMMPLPPRPPPGFRMPPPFRPPPLPPFPWPPVPPDAHIPNAAREYNPFPFPFPFPFPFPNPFPNPNPNPNPNPNPNPNPNQNFAGPRYRY
Protein: PWWP domain-containing DNA repair factor 3A (PWWP3A) (Mutated melanoma-associated antigen 1) (MUM-1) (PWWP domain-containing protein MUM1) (Protein expandere) (Q2TAK8)
Organism: Homo sapiens (Human)
Function: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Subcellular location: Nucleus {ECO:0000269|PubMed:20347427}. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH-ubiquinone oxidoreductase chain 3
- NADH-ubiquinone oxidoreductase chain 4
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
Sequence:
MADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR
Protein: Glyoxal oxidase-related protein (Q9SVX6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Trafficking protein particle complex subunit
- Probable pectinesterase/pectinesterase inhibitor 64
- Expressed protein
- Nicotinamide adenine dinucleotide transporter 1, chloroplastic
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- DNA repair endonuclease UVH1
- Calcium-dependent lipid-binding family protein
- Ricin B-like lectin EULS3
- Haloacid dehalogenase-like hydrolase
- Alpha-glucosidase 2
Sequence:
MINSKNTFIVATTILCLSMAILSEGQANPFLLQLDRWEMLLPSIGISAMHMQLLHNGMVIMFDRTDFGTSNVSLPGGICRYDPTDTAEKFDCSAHSVLYDVVSNTYRPLNVQTDTWCSSGAVLPNGTLVQTGGYNDGERAARMFSPCGYSDTCDWIEFPQYLSQRRWYATNQILPDGRIIVVGGRRQFNYELFPRHDSRSRSSRLEFLRETSDGSNENNLYPFIHLLPDGNLFVFANTRSIVFDYKKNRIVKEFPEIPGGDPRNYPSSGSSILFPLDDTNDANVEVEIMVCGGSPKGGFSRGFTRATSTCGRLKLSDQSPSWEMETMPLPRVMGDMLLLPTGDVIIVNGAGAGTAGWEKARDPIIQPVIYQPFDHLFTVMSTPSRPRMYHSSAILLPDGRVLVGGSNPHVYYNFTNVEYPTDLSLEAYSPPYLFFTSDPIRPKILLTSDKVLSYKRLFNVDFSIAQFLTVDLLSVRIVAPSFTTHSFAMNQRMVILKLLSVTRDQLTNSYRVSALGPSTAEIAPPGYYMIFLVHAGIPSSAAWVQIE
Protein: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, apicoplast (HMBPP reductase) (EC 1.17.7.4) (Q8I295)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
Subcellular location: Plastid, apicoplast {ECO:0000305}.
Interaction partners:
- 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
- Homocysteine S-methyltransferase, putative
- S-adenosylmethionine synthase
- Bifunctional farnesyl/geranylgeranyl diphosphate synthase
- Glycine cleavage system H protein
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, putative
- Serine hydroxymethyltransferase
- Serine hydroxymethyltransferase
- Adenosylhomocysteinase
- Aminomethyltransferase, putative
Sequence:
MSVTTFCSLKKTDKCNIYISKRAFSVFLFYLFFFLFFHFYFLCSSSFAVIIHESEKRKNIMRRKRSILQIFENSIKSKEGKCNFTKRYITHYYNIPLKIKKHDLPSVIKYFSHKPNGKHNYVTNMITQKNRKSFLFFFFLYNKYFFGKQEQIRKMNYHEEMNKINIKNDGNRKIYMYPKNDIHEEDGDHKNDVEINQKRNEQNCKSFNDEKNENARDPNKILYLINPRGFCKGVSRAIETVEECLKLFKPPIYVKHKIVHNDIVCKKLEKEGAIFIEDLNDVPDGHILIYSAHGISPQIREIAKKKKLIEIDATCPLVNKVHVYVQMKAKENYDIILIGYKNHVEVIGTYNEAPHCTHIVENVNDVDKLNFPLNKKLFYVTQTTLSMDDCALIVQKLKNKFPHIETIPSGSICYATTNRQTALNKICTKCDLTIVVGSSSSSNAKKLVYSSQIRNVPAVLLNTVHDLDQQILKNVNKIALTSAASTPEQETQKFVNLLTNPPFNYTLQNFDGAHENVPKWKLPKNLLHMIKEREK
Protein: Small ribosomal subunit protein eS24A (40S ribosomal protein S24-A) (RP50) (P0CX31)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein eS4A
- Small ribosomal subunit protein eS1A
- Small ribosomal subunit protein eS10A
- Small ribosomal subunit protein uS14B
- Small ribosomal subunit protein eS27A
- Small ribosomal subunit protein uS11B
- Small ribosomal subunit protein eS7B
- Small ribosomal subunit protein uS5
- Nucleolar complex protein 14
- Large ribosomal subunit protein uL18
Sequence:
MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
Protein: Ubiquitin-fold modifier-conjugating enzyme 1 (Q38EZ0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ubiquitin-like modifier-activating enzyme 5
- Ubiquitin-fold modifier 1
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS2
- UfSP1/2/DUB catalytic domain-containing protein
Sequence:
MDPAVRESVSRIPLLKTKAGPRDGEQWTQRLKEEYTSLIQFVENNKASDNHWFKLESNEAGTRWYGTCWTYYKNERYEFNMNFDLAVTYPQAPPEIALPELEGKTVKMYRGGKICMTTHFFPLWARNVPYFGISHALALGLGPWLSIEVPAMVEDGVLKPKKVES
Protein: Rab3 interacting molecule, isoform AA (A0A0B4KG75)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MDEMPDLSHLTPHERMQIENVLMRQKQEEEKQNEIMRRKQDEVVTLEMQIRQRSEQQKKAGVELDATCHICLKTKFADGVGHICHYCNIRCCARCGGKVTLRSNKVIWVCILCRKKQELLSKTGQWINKTAAQQDGFIRRIEPDGSSDISQHPIVDPHDTTDKRPKLERTRSAAEKENLPMQRAGSMLRRQYSQQEQPTNRRLSASDSGMDPVMSPGQQMQHHQQQQRARMQPMNPQQAQQGYGMQQQQQPRSGGAYPDDDPRYYQGELDGLMRQHPHLAHPSQVQPQHTPQSHSQQQQSQHQQQHLMPQQHRPSPQQHSQQQQQQQQHSQQFAARQQQHQQQQHQQQVQQSYHAQIHQQPQQHPHPHSQQQQHHQQMQHQHGQSVPQMGGYQKPPPLTRNLTISGGHAMDSSAYSQQQQQQQRRALAGSQYASQQQRSFSSSEEEFQHQLLAAQGAVTVTAGSDYDGGRLQVRTSLDPWRQQRSLNERDLLSSGGGGGGGVGGADFRHLSHATQRLYASADQRDRYELQLQHRERLEQYPLTRTARLDVQQRNSLNRSNHERQFSGGGAGVGPGGAGGGGAAGAYRRAPPLAAAGGGGSSSSSTTSSSYYPQSKPQIVIGPGSGYDRGSGSMASMASAAAATAADAQGQAARNSQRGGLLGATRGGGGSSSVSSTEAAYWDEPATSSSSSAAQDSRRFTERRIKKTVRFDAHDEEASILASSSLPPVTAILPSTAVDVGAATILSSGKSLDAVGVGGADWSRWEAERQGSQDSATKDSGIDTSSTFTSSEDSNRGDGPKASATGYYRRGGGNGVGSAIGPGGMSLSQRSHSAAPSDGYHSSGVGGAASGGPAYGYRSTSPRRGSLSPPDDRYIDYPVLPVHGSSPNAPSVYQGPGGVSSAAASASQQQRFQSRSATATPTGSPKKRQLPQVPQTSRSAMLRDRLGQDFDERLASGGRFGRHRTRQPHHQATYRSTGMGGWERHYTGLSDSDLHSMDARMRPRHSLSPDKDFMGEFGDSDMESVVSVTSSAFSTQSERPRTSRGLSEYDKDKNGAEEAGGSKSAEGAGAEDKVDGSLSDTANDRKKGGGVDQERSPKGGSGMGKKSNSTSQLSATGRKRRMGFGKKGKNSFTVHRSEEVLPGDITRELRTGGGLGVSLGGAGGAAGGSGGAGGGGLSRGSSSEVDAIEQFFGDGAGGERFSPSLRNDGALNEFVDGLGPGQLVGRQVLGAPSLGDIQLSLCHQKGCLEVEVIRARGLQQKAQSKMLPAPYVKVYLVSGKRCVDKMKTSSARRTLDPLYQQQLVFKQSYTGCILQITVWGDYGRIEKKVFMGVAQIMLDDLNLSNIVIGWYKLFGTTSL
Protein: Aha1 domain-containing protein (Q9LHL7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase CYP40
- Heat shock protein 90-1
- Heat shock protein 90-2
- Endoplasmin homolog
- Heat shock protein 90-3
- Protein SGT1 homolog A
- Heat shock protein 90-6, mitochondrial
- Heat shock protein 90-5, chloroplastic
- Heat shock protein 90-4
- 26S proteasome regulatory subunit S10B homolog B
Sequence:
MAKFGEGDKRWIVEDRPDGTNVHNWHWSETNCLEWSRNFFTKQFSGVDILSGEGNLFIKVSKIEKVEGEAYVNVRKGKIIPGYELNVSLSWEGEAKDSDGKTLLKADGLVDMPYISDENADEDPEIRFSVKDEGPIGRTLKEAMVKKGKEIILEKVRVYVEAMARGGPCRDELESKKVAPKSVAAGSATVAVEKSGAAPVVSAAAVESKVVKEKKKAKTKEGFKTITMTEKFNCRARDLYEILMDENRWKGFTQSNAKISKDVNGPISVFDGSVTGMNLELEEGKLIVQKWRFGSWPDGLDSTVKIVFEEPQPGVTIVNLTHTDVPEEDRYGNATVVENTERGWRDLIFHRIRAVFGFGI
Protein: Coiled-coil quantitatively-enriched protein 1 (Structural maintenance of chromosomes protein ccq1) (SMC protein ccq1) (Q10432)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the meiotic bouquet that facilitates meiotic nuclear reorganization of the telomeres to the centrosome. Links telomeres to the meiotic centrosome component pcp1. Essential for the formation of normal telomere clusters during meiotic prophase. Required for telomere length regulation and chromosome segregation. Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).
Subcellular location: Nucleus, nucleoplasm. Chromosome, telomere. Note=Associates with major heterochromatin, sub-telomeres, rDNA and the mat locus.
Interaction partners:
- Protection of telomeres protein tpz1
- Protection of telomeres protein poz1
- Telomere length regulator taz1
- DNA-binding protein rap1
- Telomerase reverse transcriptase
- Histone deacetylase clr3
- Protection of telomeres protein 1
- Protein ten1
- Protein stn1
- Telomere elongation protein est1
Sequence:
MSEINDFTNSIIINESDTKYEVYSEVNSSNRWIAKEDCPSPLEDVWLLKLAGHKRKLEEPLSCMRNEEPASKQREIEKFLRTDLDHSENDFLTQEVDEFPSTQQLFPIPLQNDTAFDSSEESITKSSKSSFSVLDIGLPMSALQRKMMHRLVQYFAFCIDHFCTGPSDSRIQEKIRLFIQSAHNIAKHPSLYDTEVRNPSAAESTNSHVSLDASNFSSYAENSSKFLFLQELFKNLSPSYSKTFFLFISNQFLANTLTQWLKSQNIDAELWAEEDAKTSQHPAIWICVSKKAPSASHFLQSCPDLSATIFYDIEAYMSVTSSLPSIQSLVLRLIHLGSIEHAIKCFQSSYNASFLVNIVGVVATLSSSSEENSEASNLSTLFEKSGNFEEILGSESHSSITEKTRDIAKNVATWLKNGENFSSWPLPPLMDLASLSVAEPRDSQPSVSQVNDTFVKSSDSTFPSSQSMQSPSKLHSLTSNATDLLSSSSLKKNFFSQQEADEVELSNNYDLQGAAVQYLQRRLRMVEDELHEAINSKNVQQSRSEELEQQISKLTDNLQEYRNTVRELKLDLEKSKKKNEDLSKLEVEKVEEIANLKKELTHLAKQQEFGFKYVQEFSNEDLQGKLIEANEKNYKLTQLLKTQKEDADFITNQYQNASTFAAEQSKEVAKLQAECKRLQAINSKVMEEVKVYNDSRVEALLAKVSSLEETLKILEQKSLPKFTPHNQSPRIIDSN
Protein: X11Lbeta, isoform D (M9PGU7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQQYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIKAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPQDIDDAPKPNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI
Protein: Small ribosomal subunit protein uS10m (28S ribosomal protein S10, mitochondrial) (MRP-S10) (S10mt) (Q9VFB2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:P82664}.
Interaction partners:
- LD06441p
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein bS6m
- Mitochondrial ribosomal protein S11
- Small ribosomal subunit protein mS29
Sequence:
MKMHMKHLDLYSQAIKTLRWTQPMRALSTVNTSSGVQGNLSPAAPAPEPDKLYSKLEIELRGIDPAVLKSYTWFATTAAEHLGIEKGKCWSPRKAHHERMTLLKSVHIYKKHRVQYEVRTHFRYMNFHKLTGSTLDTFLEYIERNLPEGVALQASRTELQEIPEHLRQPPEQV
Protein: Olfactory receptor 52B4 (Olfactory receptor OR11-3) (Q8NGK2)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MPTVNHSGTSHTVFHLLGIPGLQDQHMWISIPFFISYVTALLGNSLLIFIILTKRSLHEPMYLFLCMLAGADIVLSTCTIPQALAIFWFRAGDISLDRCITQLFFIHSTFISESGILLVMAFDHYIAICYPLRYTTILTNALIKKICVTVSLRSYGTIFPIIFLLKRLTFCQNNIIPHTFCEHIGLAKYACNDIRINIWYGFSILMSTVVLDVVLIFISYMLILHAVFHMPSPDACHKALNTFGSHVCIIILFYGSGIFTILTQRFGRHIPPCIHIPLANVCILAPPMLNPIIYGIKTKQIQEQVVQFLFIKQK
Protein: Lysophospholipid acyltransferase (LPLAT) (EC 2.3.1.23) (EC 2.3.1.51) (1-acyl-sn-glycerol-3-phosphate acyltransferase) (AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (O42916)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Membrane-bound O-acyltransferase that mediates the incorporation of unsaturated acyl chains into the sn-2 position of phospholipids.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Uncharacterized acyltransferase C1718.04
- Uncharacterized acyltransferase C1851.02
- Phosphatidylserine decarboxylase proenzyme 2, mitochondrial
- Putative phosphatidate cytidylyltransferase
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
- Phosphatidylserine decarboxylase proenzyme 3
- Putative lysophosphatidic acid:oleoyl-CoA acyltransferase
- Probable diacylglycerol pyrophosphate phosphatase 1
- Nuclear elongation and deformation protein 1
- Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.10
Sequence:
MAYLIDIPFEYFSSFLGVHPDQLKLLFCFLSAYPFAGILKRLPSAPWIRNLFSISIGLFYLIGVHHLYDGVLVLLFDALFTYFVAAFYRSSRMPWIIFIVILGHTFSSHVIRYIYPSENTDITASQMVLCMKLTAFAWSVYDGRLPSSELSSYQKDRALRKIPNILYFLGYVFFFPSLLVGPAFDYVDYERFITLSMFKPLADPYEKQITPHSLEPALGRCWRGLLWLILFITGSSIYPLKFLLTPKFASSPILLKYGYVCITAFVARMKYYGAWELSDGACILSGIGYNGLDSSKHPRWDRVKNIDPIKFEFADNIKCALEAWNMNTNKWLRNYVYLRVAKKGKRPGFKSTLSTFTVSAMWHGVSAGYYLTFVSAAFIQTVAKYTRRHVRPFFLKPDMETPGPFKRVYDVIGMVATNLSLSYLIISFLLLNLKESIHVWKELYFIVHIYILIALAVFNSPIRSKLDNKIRSRVNSYKLKSYEQSMKSTSDTDMLNMSVPKREDFENDE
Protein: Zinc finger and SCAN domain-containing protein 9 (Cell proliferation-inducing gene 12 protein) (PRD51) (Zinc finger protein 193) (O15535)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
Interaction partners:
- Zinc finger protein 446
Sequence:
MNTNSKEVLSLGVQVPEAWEELLTMKVEAKSHLQWQESRLKRSNPLAREIFRRHFRQLCYQETPGPREALTRLQELCYQWLRPHVSTKEQILDLLVLEQFLSILPKELQGWVREHCPESGEEAVILLEDLERELDEPQHEMVAHRHRQEVLCKEMVPLAEQTPLTLQSQPKEPQLTCDSAQKCHSIGETDEVTKTEDRELVLRKDCPKIVEPHGKMFNEQTWEVSQQDPSHGEVGEHKDRIERQWGNLLGEGQHKCDECGKSFTQSSGLIRHQRIHTGERPYECNECGKAFSRSSGLFNHRGIHNIQKRYHCKECGKVFSQSAGLIQHQRIHKGEKPYQCSQCSKSYSRRSFLIEHQRSHTGERPHQCIECGKSFNRHCNLIRHQKIHTVAELV
Protein: Cullin 2 (D4A0H4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYAETKIFLENHVRHLYKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQYIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQNILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQGIFVSPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHSECHSIIRHERKNDMANMYVLLRAVSSGLPHMIEELQRHIHDEGLRATSNLTQEHMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKLAKYCDNLLKKSAKGMTENEVEDKLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLNNKFNNFIRNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMSFSSKRTKFKITTSMQKDTPQELEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA
Protein: Diadenosine hexaphosphate hydrolase (Ap6A hydrolase) (EC 3.6.1.61) (ATP-generating (di)nucleotide polyphosphate hydrolase) (ATP-generating Ap6A hydrolase) (Nudix protein) (Q75UV1)
Organism: Thermus thermophilus
Function: Specifically hydrolyzes (di)adenosine polyphosphates but not ATP or diadenosine triphosphate, generating ATP as the product. Diadenosine hexaphosphate (Ap6A) is the preferred substrate and hydrolysis yields 2 ATP. It is the only enzyme that symmetrically hydrolyzes Ap6A. It also hydrolyzes diadenosine pentaphosphate (Ap5A), diadenosine tetraphosphate (Ap4A) and adenosine tetraphosphate (p4A).
Interaction partners:
Sequence:
MELGAGGVVFNAKREVLLLRDRMGFWVFPKGHPEPGESLEEAAVREVWEETGVRAEVLLPLYPTRYVNPKGVEREVHWFLMRGEGAPRLEEGMTGAGWFSPEEARALLAFPEDLGLLEVALERLPL
Protein: HTH-type transcriptional activator BauR (Q9I6Z9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in the degradation of beta-alanine. BauR activates the transcription of the bauABCD operon.
Interaction partners:
- Beta-alanine--pyruvate aminotransferase
- Probable transcriptional regulator
- DhcR, transcriptional regulator
- Probable transcriptional regulator
- EamA domain-containing protein
- Probable major facilitator superfamily
- (S)-ureidoglycine aminohydrolase cupin domain-containing protein
- ABC transporter substrate-binding protein
- Probable periplasmic spermidine/putrescine-binding protein
- Probable transcriptional regulator
Sequence:
MAKSRNPSLGQVSDFDIRLLRIFKTIVECGSFSAAESTLGLSRSAISLHMGDLEKRLGMRLCQRGRAGFALTDEGREVYRATQTLLAALEGFRAEVNDLHQHLRGELNIGIINNLVTLPQMRITHALSALKGQGPQVRINIGMTTPNEIELGVLDGHLHVGVVPLISPLSGLEYLPLYDEHAQLYCSRGHALFERADGDIAVDEVLAADAVAPSYRLPAEAQARHQELNNSASASDREGMAFLILTGNFIGYLPSHYAADWVAAGMLRPLLPERFHYAIALTIVTRKGRRPNLVLERFLEAVAVS
Protein: COX4 neighbor, isoform CRA_a (Neighbor of COX4) (Q53Y03)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004397}.
Interaction partners:
Sequence:
MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDHSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFSDTALIMVDNTKFTMDCVAPTIHVYEHHENRWRCRDPHHDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC