wanglab/gogpt-training-data huggingface dataset:
Protein: Transporter (F6SPX0)
Organism: Monodelphis domestica (Gray short-tailed opossum)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Collectrin, amino acid transport regulator
- Angiotensin-converting enzyme
- Angiotensin-converting enzyme
Sequence:
MNKPNSKWKWAGLAAVSGWAGRALEITTKAHRQAPRNPGTRRHHRLGVSGKPREPIGSALGAAMVEMEKARPVWNNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGGFLIPYIIMLVVEGMPLLYLELAVGQRMRQGSIGAWNTISPYLRGVGIASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSSCPLNSNLTSYDEECEKASSTQYFWYRKTLNISPSIEENGGIQWEQALCLILAWLVVYLCILRGTESTGKVVYVTASLPYCVLIIYLVRGLTLHGAINGLAYMFTPKIEQLANPQTWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSSTSIFASIVTFSIYGFKATFNYENCINKVILLLTNTFDLEDGFLTPGNLEETKDYLASAYPTEYSKIFPDIKNCSLESELDTAVQGTGLSFIVYTEAIKNMEVSQLWSVLYFVMLLMLGIGSMLGNTAAILTPLTDSNTISSRLPKEAISGLVCLISCAIGLVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAICYVYGLKRFENDLQVMTGCKPNWYWKIIWAFVSPLLIIGLFIFYLTDYILKGTLQYQAWDATQGQLVTRDYPNYALAVIGLLVASSTMCIPLVALGTFIMNRWKKGKTVSV
Protein: Esterase YbfF (EC 3.1.-.-) (P75736)
Organism: Escherichia coli (strain K12)
Function: Displays esterase activity toward palmitoyl-CoA, malonyl-CoA and pNP-butyrate.
Interaction partners:
- Tryptophan--tRNA ligase
- Esterase YpfH
- 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
- Esterase YqiA
- Esterase FrsA
- Pimeloyl-[acyl-carrier protein] methyl ester esterase
Sequence:
MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHNIIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALASDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQFLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLLAQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND
Protein: Protein amnionless [Cleaved into: Soluble protein amnionless] (Q6UKI2)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: Membrane-bound component of the endocytic receptor formed by AMN and CUBN. Required for normal CUBN glycosylation and trafficking to the cell surface. The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12. Required for normal CUBN-mediated protein transport in the kidney.
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:Q9BXJ7}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9BXJ7}. Cell membrane {ECO:0000305|PubMed:15845892}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9BXJ7}. Endosome membrane {ECO:0000250|UniProtKB:Q9BXJ7}. Membrane, coated pit {ECO:0000250|UniProtKB:Q9BXJ7}.; SUBCELLULAR LOCATION: [Soluble protein amnionless]: Secreted {ECO:0000269|PubMed:15845892}.
Interaction partners:
Sequence:
MGALGRALLWLQLCALARAAYKLWVPTTDFEAAANWSQNRTPCAGAVVQFPADKAVSVVVRASHGFSDMLLPRDGEFVLASGAGFGAADAGRDPDCGAGAPALFLDPDRFSWHDPRLWRSGDAARGLFSVDAERVPCRHDDVVFPPDASFRVGLGPGARPARVRSVQVLGQTFTRDEDLAAFLASRAGRLRFHGPGALRVGPGACADPSGCVCGDAEVQPWICAALLQPLGGRCPPAACPDALRPEGQCCDLCGAIVSLTHGPTFDIERYRARLLRAFLPQYPGLQAAVSKVRRRPGPHTEVQVVLAETGPQPGGAGRLARALLADVAEHGEALGVLSATARESGAPVGDGSAAGPLGSGSRAGLAGGVAAGLLLLLLALAAGLLLLRRAPRLRWTKRERLVATPVEAPLGFSNPVFDVAGSVGPVPRTPQPPPAQQAGSSSTSRSYFVNPLFAEAEA
Protein: Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2) (Q5SF07)
Organism: Mus musculus (Mouse)
Function: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts (By similarity). Increases MYC mRNA stability by binding to the coding region instability determinant (CRD) and binding is enhanced by m6A-modification of the CRD (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q9Y6M1}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q9Y6M1}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa. In response to cellular stress, such as oxidative stress, recruited to stress granules (By similarity). {ECO:0000250}.
Interaction partners:
- High mobility group protein HMGI-C
- Insulin-like growth factor 2
- ATP-dependent RNA helicase A
- YTH domain-containing family protein 1
- YTH domain-containing protein 1
- N
- Heterogeneous nuclear ribonucleoproteins A2/B1
- Heterogeneous nuclear ribonucleoproteins C1/C2
- Alpha-ketoglutarate-dependent dioxygenase FTO
- Threonylcarbamoyladenosine tRNA methylthiotransferase
Sequence:
MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGKVELHGKIMEVDYSVSKKLRSRRIQIRNIPPHLQWEVLDGLLAEYGTVENVEQVNTDTETAVVNVTYMTREEAKLAIEKLSGHQFEDYSFKISYIPDEEVSSPSPPHRAREQGHGPGSSSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEVPLKILAHNGFVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVRGTIEACANAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLPPPAGPRGVPPSPPYHPFATHSGYFSSLYPHHHFGPFPHHHSYPEQETVSLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQRYPQGVAPQRSK
Protein: 5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha (AMPKA) (EC 2.7.11.1) (Protein kinase, AMP-activated, alpha subunit) (SNF1/AMP-activated kinase catalytic subunit) (Sucrose non-fermenting protein snfA) (Q54YF2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Activated enzyme phosphorylates target proteins and initiates downstream signaling pathways that shift metabolism from anabolic to catabolic pathways. Acts as a highly sensitive cellular energy sensor.
Interaction partners:
- Association with the SNF1 complex
- 5'-AMP-activated protein kinase subunit gamma
- Protein raptor homolog
Sequence:
MSSYQQNPIGSFGGLYGSGGIEKSSQIIGNYRLDKTLGIGSFGKVKLAEHIRTGVKVAIKILNRTKIKNLKMDEKIRREIQNMKLFRHPHIIKLYEVIETTTDIFMVMEYVTGGELFEYIVKNGKLLEDESRRLFQQMISGVDYCHHHMVVHRDLKPENLLLDPINKCIKIADFGLSNMMQDGDFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYAFLCAKLPFDDESIPMLFKKIREGVFSIPDFVSPSCADLIKKMLVVDPVKRITIHEIRNHPWFQVKLPKYLSSPHTFLSKSIQTINNSILNEMVQVYAPIDRERIIEELQKSGEVNDLIVSYHLLVDSKRGSYENEINSPNLVSPITTPIMSSAQKSPIMFTTTTGFNPSNSNSISNNNNNNNNNNNNTTNNNNNTTNNNNSIINNNNINNNNINNNNNNNNNNINNNNIINNNNNNNNNNNNNNNNNNNNNNNNNNNSSISGGTEVFSISPNLNNSYNSNSSGNSNGSNSNNNSNNNTNNDNNNNNNNNNNNNNNNNNNNNNNNNNNNCIDSVNNSLNNENDVNNSNINNNNNNNSDDGSNNNSYEGGGDVLLLSDLNGNNQLGGNDNGNVVNLNNNFQLLNSLDLNSDIQTQPHRKWYLGAISQLPPHEIMGEIYRALKKVGFEWKLTGPYQLRCRMVNGKPIKLVLQLFRVAENRYLLDIKKIEGEIFIFFDICSLMLEELNL
Protein: Arginine biosynthesis bifunctional protein ArgJ, chloroplastic [Cleaved into: Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain] [Includes: Glutamate N-acetyltransferase (GAT) (EC 2.3.1.35) (Ornithine acetyltransferase) (OATase) (Ornithine transacetylase); Amino-acid acetyltransferase (EC 2.3.1.1) (N-acetylglutamate synthase) (AGS)] (Q9ZUR7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
Subcellular location: Plastid, chloroplast {ECO:0000255|HAMAP-Rule:MF_03124, ECO:0000269|PubMed:18431481}.
Interaction partners:
- Probable amino-acid acetyltransferase NAGS1, chloroplastic
- Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic
- Acetylglutamate kinase, chloroplastic
- Acetylornithine aminotransferase, chloroplastic/mitochondrial
- Ornithine transcarbamylase, chloroplastic
- Probable amino-acid acetyltransferase NAGS2, chloroplastic
- Argininosuccinate lyase, chloroplastic
- Acetylornithine deacetylase
- Argininosuccinate synthase, chloroplastic
- At1g44820
Sequence:
MHSCSHTHFVSFKLPHFFAPKSFVVSSRRELRVFAVATTVEEASGNIPAAPISLPQGSWKQIAGGVTAAKGFKAAGMYAGLRAAGKKPDLALVTCDVEAVAAGVFTTNVVAAAPVVYCKKVLETSKTARAVLINAGQANAATGDAGYQDMLDCVGSIATLLKVKPEEVLIESTGVIGQRIKKEELLHALPTLVNSRSDSVEEADSAAVAITTTDLVSKSVAVESQVGGIKIRVGGMAKGSGMIHPNMATMLGVITTDALVESDIWRKMVKVAVNRSFNQITVDGDTSTNDTVIALASGLSGSPSISSLNCKEAAQLQACLDAVMQGLAKSIAWDGEGATCLIEVTVKGTETEAEAAKIARSVASSSLVKAAVYGRDPNWGRIAAAAGYAGVSFQMDKLKISLGEFSLMESGQPLPFDRDGASNYLKKTGEVHGTVTIDISVGDGAAIGKAWGCDLSYDYVKINAEYTS
Protein: Rho GTPase-activating protein 17 (Neuron-associated developmentally-regulated protein) (Nadrin) (Rho-type GTPase-activating protein 17) (Q3UIA2)
Organism: Mus musculus (Mouse)
Function: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1 (By similarity).
Subcellular location: Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Note=Associates with membranes and concentrates at sites of cell-cell contact. {ECO:0000250}.
Interaction partners:
- Angiomotin
- Cell division control protein 42 homolog
- Angiomotin-like protein 1
- Angiomotin-like protein 2
- InaD-like protein
- Cdc42-interacting protein 4
Sequence:
MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGTDAERRHKKLPLTALAQNMQEASAQLEESLLGKMLETCGDAENQLALELSQHEVFVEKEIMDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPLATPNSNHSSHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHIAPAFQPPLPPTDGNALAPAGPEPPSQSSRADSSSGGGPVFSSTGILEQGLSPGDSSPPKPKDSVSAAVPAAGRNSNQMTTVPNQAQTGGNSHQLSVSTPHSAAGPSPHTLRRAVKKPAPAPPKPGNLPPGHPGGQSSPGTGTSPKPSARSPSPPQQQQQQQQQQQQQQQQQTPGMRRCSSSLPPIQAPSHPPPQPPTQPRLGEQGPEPGPTPPQTPTPPSTPPLAKQNPSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPHPPGTHTVDGGLTSSVPTASRIVTDTNSRVSESLRSIFPEIHSDLASKEVPGHILLDIDNDTESTAL
Protein: 17-beta-hydroxysteroid dehydrogenase type 1 (17-beta-HSD 1) (EC 1.1.1.51) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 1) (EC 1.1.1.62) (Placental 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 1) (P14061)
Organism: Homo sapiens (Human)
Function: Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Also has 20-alpha-HSD activity. Uses preferentially NADH.
Subcellular location: Cytoplasm.
Interaction partners:
- 17-beta-hydroxysteroid dehydrogenase type 2
- Dehydrogenase/reductase SDR family member 11
- 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
- Aromatase
- 17-beta-hydroxysteroid dehydrogenase type 3
- Aldo-keto reductase family 1 member C3
- Very-long-chain 3-oxoacyl-CoA reductase
- Sulfotransferase 1E1
- (3R)-3-hydroxyacyl-CoA dehydrogenase (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (KAR alpha subunit) (Estradiol 17-beta-dehydrogenase 8) (Protein Ke6) (Ke6) (Testosterone 17-beta-dehydrogenase 8)
- Cytochrome P450 1B1
Sequence:
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGGGAGPGAEDEAGRGAVGDPELGDPPAAPQ
Protein: Homeobox protein OTX2 (Orthodenticle homolog 2) (P80206)
Organism: Mus musculus (Mouse)
Function: Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P32243}.
Interaction partners:
- POU domain, class 5, transcription factor 1
- Hepatocyte nuclear factor 3-beta
- Homeobox protein SIX6
- Forkhead box protein G1
- Homeobox protein SIX3
- Transcription factor SOX-2
- Photoreceptor-specific nuclear receptor
- LIM homeobox transcription factor 1-alpha
- Fibroblast growth factor 5
- Nuclear receptor ROR-beta
Sequence:
MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKSSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
Protein: Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) (Q13733)
Organism: Homo sapiens (Human)
Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16175638}; Multi-pass membrane protein {ECO:0000269|PubMed:16175638}. Note=In mature sperm, located in the principle piece of the sperm flagellum.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit gamma
- Sodium/potassium-transporting ATPase subunit beta-1
- Sodium/potassium-transporting ATPase subunit beta-3
- Sodium/potassium-transporting ATPase subunit beta-2
- Protein ATP1B4
- Sodium/potassium-transporting ATPase subunit alpha-3
- Sodium/potassium-transporting ATPase subunit alpha-2
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 3
- Phospholemman
Sequence:
MGLWGKKGTVAPHDQSPRRRPKKGLIKKKMVKREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY
Protein: Homeobox-leucine zipper protein HDG1 (HD-ZIP protein HDG1) (Homeodomain GLABRA 2-like protein 1) (AtHD-GL2-1) (Homeodomain transcription factor HDG1) (Protein HOMEODOMAIN GLABROUS 1) (Q9M2E8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor (By similarity). Promotes cuticle development probably by modulating the expression of the downstream genes BDG and FDH, possibly repressed in a CFL1-dependent manner. Involved, together with PDF2, in the regulation of flower organs development by promoting the expression of APETALA 3 (AP3) in the epidermis and internal cell layers of developing flowers. In opposition to BBM, seems to promote cell differentiation and giant cell identity via transcriptionnal repression of meristem and cell proliferation genes.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- ATP-dependent RNA helicase
- Ethylene-responsive transcription factor SHINE 3
- Ethylene-responsive transcription factor WIN1
- Exosome complex component RRP45B
- Transcription factor MYB16
- Pleckstrin homology
- At4g14500
- Ethylene-responsive transcription factor SHINE 2
- Polyketide cyclase/dehydrase and lipid transport superfamily protein
- Peptidyl-prolyl cis-trans isomerase CYP19-3
Sequence:
MNFNGFLDDGAGASKLLSDAPYNNHFSFSAVDTMLGSAAIAPSQSLPFSSSGLSLGLQTNGEMSRNGEIMESNVSRKSSRGEDVESRSESDNAEAVSGDDLDTSDRPLKKKKRYHRHTPKQIQDLESVFKECAHPDEKQRLDLSRRLNLDPRQVKFWFQNRRTQMKTQIERHENALLRQENDKLRAENMSVREAMRNPMCGNCGGPAVIGEISMEEQHLRIENSRLKDELDRVCALTGKFLGRSNGSHHIPDSALVLGVGVGSGGCNVGGGFTLSSPLLPQASPRFEISNGTGSGLVATVNRQQPVSVSDFDQRSRYLDLALAAMDELVKMAQTREPLWVRSSDSGFEVLNQEEYDTSFSRCVGPKQDGFVSEASKEAGTVIINSLALVETLMDSERWAEMFPSMVSRTSTTEIISSGMGGRNGALHLMHAELQLLSPLVPVRQVSFLRFCKQHAEGVWAVVDVSIDSIREGSSSSCRRLPSGCLVQDMANGYSKVTWIEHTEYDENHIHRLYRPLLRCGLAFGAHRWMAALQRQCECLTILMSSTVSTSTNPSPINCNGRKSMLKLAKRMTDNFCGGVCASSLQKWSKLNVGNVDEDVRIMTRKSVNNPGEPPGIILNAATSVWMPVSPRRLFDFLGNERLRSEWDILSNGGPMKEMAHIAKGHDRSNSVSLLRASAINANQSSMLILQETSIDAAGAVVVYAPVDIPAMQAVMNGGDSAYVALLPSGFAILPNGQAGTQRCAAEERNSIGNGGCMEEGGSLLTVAFQILVNSLPTAKLTVESVETVNNLISCTVQKIKAALHCDST
Protein: ADAM33 protein (Q08AM2)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MGWRPRRARGTPLLLLLLLLLLWPVPGAGVLQGHIPGQPVTPHWVLDGQPWRTVSLEEPVSKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLAPNHTDHCHYQGRVRGFPDSWVVLCTCSGMSGLITLSRNASYYLRPWPPRGSKDFSTHEIFRMEQLLTWKGTCGHRDPGNKAGMTSLPGGPQSRGRREARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLRTLDIQVALTGLEVWTERDRSRRQLRAFFRKGGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCGPGQECRDLCCFAHNCSLRPGAQCAHGDCCVRCLLKPAGALCRQAMGDCDLPEFCTGTSSHCPPDVYLLDGSPCARGSGYCWDGACPTLEQQCQQLWGPGSHPAPEACFQVVNSAGDAHGNCGQDSEGHFLPCAGRDALCGKLQCQGGKPSLLAPHMVPVDSTVHLDGQEVTCRGALALPSAQLDLLGLGLVEPGTQCGPRMVCQSRRCRKNAFQELQRCLTACHSHGVCNSNHNCHCAPGWAPPFCDKPGFGGSMDSGPVQAENHDTFLLAMLLSVLLPLLPGAGLAWCCYRLPGAHLQRCSWGCRRDPACSGPKDGPHRDHPLGGVHPMELGPTATGQPWPLDPENSHEPSSHPEKPLPAVSPDPQDQVQMPRSCLW
Protein: Neuromedin-U receptor 1 (NMU-R1) (G-protein coupled receptor 66) (G-protein coupled receptor FM-3) (Q9HB89)
Organism: Homo sapiens (Human)
Function: Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Neuromedin-U
- Neuromedin-S
- Guanine nucleotide-binding protein G
- Neuromedin-U receptor 2
- Guanine nucleotide-binding protein G
- Pro-opiomelanocortin
Sequence:
MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETDPS
Protein: Peptidyl-prolyl cis-trans isomerase cypE (PPIase cypE) (EC 5.2.1.8) (Cyclophilin cypE) (Rotamase cypE) (Q9NI62)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Plays a role in protein folding, transport and assembly.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11690648}. Nucleus {ECO:0000269|PubMed:11690648}.
Interaction partners:
- Protein snwA
- Cell division cycle 5-like protein
- 116 kDa U5 small nuclear ribonucleoprotein component
- WD40 repeat-containing protein
- Pre-mRNA-splicing factor SYF2
- Pre-mRNA-processing-splicing factor 8 homolog
- Intron-binding protein aquarius
- FK506-binding protein 1
- Protein BUD31 homolog
- peptidylprolyl isomerase
Sequence:
MTEQTVTLQTTVGDITLELYYNHAPKACKNFYELSKRGYYDNTIFHRLIKDFMIQGGDPLGNGRGGESIYGKKFEDEITKELKHTGAGILSMANSGVNSNGSQFFITFGPTPWLDGKHTIFGRVKSGMKVVQKMNAMQTNNDKPIDEIRIIKATAN
Protein: UNC5C-like protein (Protein unc-5 homolog C-like) (ZU5 and death domain-containing protein) (Q6R653)
Organism: Mus musculus (Mouse)
Function: Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets.
Subcellular location: Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. Cytoplasm {ECO:0000250}.
Interaction partners:
- Adhesion G protein-coupled receptor L1
- Adhesion G protein-coupled receptor L2
- Adhesion G protein-coupled receptor L3
Sequence:
MSPQESSVQPSQFLLLVGIPVASALLLAQCLRWHCCQWLPGTCRKPDDPEEPVSPSTPLPEYELPRQCPAPTLPEVAAFYQELHMPTQGQTVTRQMMHKLLVFSAREVDHRGGCLILQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHRQGLVSPVVACGPHGASFLKPCTLTFKHCAQQPSQACAYSSNTSLLDAKDWKPLGQPGTHISRDECRILLSHFSLYTCVLEAPLGQTARKWLQLAMFCSPLVPGQTHLQLRVYFLNNTPCALQWAITNEQPHGGRMRGPCQLFDFTGARADQCLKLKYISEGWENVDDSSSQLVPHLHIWHGKCPFRSFCFRRKAANGNEECSALTNEIIVTMHTFQDGLETKYVEILRFQASEEETWAVPPPVSQPPLCNRLPPELFEQLQMLLEPNSVTGNDWRRLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQELHYLMTSMERLDCASAIQNYLNRSPRGSPDRLHGGTWENHGLELDEKL
Protein: Uncharacterized protein (A0A1D8PD60)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Fgr39p
- Uncharacterized protein
Sequence:
MFRRIHPILSKQSNALQTLKSGIIFRPLSFITKPTTSTTLRTTPKIISHTLIQSRTLMSTKTTNLGPFKFTLQILTGVYCGLLIVSFGSCYLLYSDANQRQNIPFELSLDDHINAVMAINKDDVCESPRHATKHYRRLLIDLAKQELGDTTTIDESKFDNRYDVPILSTDFLIHNKSIKFINFYIDMILRYSKCLLSKGELDIAIKMLTRIVVDDDFIFFKLGDAEKLSSSSRVLAKITPDITKKISILQRSIDMLIETNKSMQIDNDYILLENSKISDELINCLNDLASNLAKLSQSQSQSQSQGQQELLNQSLQIYLSELRSLQTIRSKIESNQANQATYPLFNVDRANLIGMINTIKAHISEIMWVKGHKDKAINFSEQILQELYYDRYSDPKFGPILLNVLNNLEIMYHNLHKPEDVKRCQNLKHDVSIYEIRNRFDIPWYDRVMKRISKTIYLRTPIGLVEKGLRDRFEPRARVKELDEFEDEDDENRSQWLYPLAK
Protein: Probable pyridoxamine 5'-phosphate oxidase (Q820A5)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- anthranilate synthase
- Phenazine biosynthesis protein PhzA1
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- Phenazine biosynthesis protein PhzA2
- Phenazine biosynthesis protein PhzB1
- Trans-2,3-dihydro-3-hydroxyanthranilate isomerase
- Phenazine biosynthesis protein PhzD1
- Phenazine biosynthesis protein PhzB2
- 5-methylphenazine-1-carboxylate 1-monooxygenase
- Phenazine-1-carboxylate N-methyltransferase
Sequence:
MMGVNANISESLTGTIEAPFPEFEAPPANPMEVLRNWLERARRYGVREPRALALATVDGQGRPSTRIVVIAELGERGVVFATHADSQKGRELAQNPWASGVLYWRESSQQIILNGRAERLPDERADAQWLSRPYQTHPMSIASRQSETLADIHALRAEARRLAETDGPLPRPPGYCLFELCLESVEFWGNGTERLHERLRYDRDEGGWKHRYLQP
Protein: Ino eighty subunit 2 (P40154)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- RuvB-like protein 2
- RuvB-like protein 1
- Actin-related protein 5
- Chromatin-remodeling complex subunit IES6
- Ino eighty subunit 1
- Ino eighty subunit 3
- Ino eighty subunit 4
- Non-histone protein 10
- Ino eighty subunit 5
- Chromatin-remodeling ATPase INO80
Sequence:
MDSEASDIEAELSDSVSAGGEEYIDDDDYTEDIDDQIVTAKSSRRTARRSVPKGVRTSKRIRDKELSVEVDEDYDEEEDVLSPSKKRHLHTRSMDKRQVAATASEKSDIGDSKGNDGEIEDGILEEEESLEKELNRGGGKEVEKSEESYYAQNDVGQKGEEEQDGESGGYEDNEPSISKESDELVSVVNGNGNEEDDEVEATKENTTDSTRSTTTRSKMLLDLLEDGGSKKKLTDEEIQLRRAENARKRKNLSEKRLEEEKQDTINKLLKKRAGKSRSHLPNDDEKNDGSSSFVKPRRPYNSEGMTRILRRYEEDLFCTF