wanglab/gogpt-training-data huggingface dataset:
Protein: B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3) (P20749)
Organism: Homo sapiens (Human)
Function: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).
Subcellular location: Nucleus. Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. {ECO:0000250}.
Interaction partners:
- Nuclear factor NF-kappa-B p105 subunit
- Nuclear factor NF-kappa-B p100 subunit
- Ubiquitin carboxyl-terminal hydrolase CYLD
- Pirin
- Transcription factor RelB
- Proto-oncogene c-Rel
- Transcription factor p65
- Histone deacetylase 1
- NF-kappa-B inhibitor alpha
- Protein c-Fos
Sequence:
MPRCPAGAMDEGPVDLRTRPKAAGLPGAALPLRKRPLRAPSPEPAAPRGAAGLVVPLDPLRGGCDLPAVPGPPHGLARPEALYYPGALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLSADIAMATRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVIDILRGKATRPASTSQPDPSPDRSANTSPESSSRLSSNGLLSASPSSSPSQSPPRDPPGFPMAPPNFFLPSPSPPAFLPFAGVLRGPGRPVPPSPAPGGS
Protein: Ribosomal protein S1 (Q8HCN1)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
Sequence:
MFLVDAGLGTPKICMQDELTGLPIKRATRFENKVGSKNVVAGESLIKKRIEERFFIDLVAGESLIKERAAARFNDFVGFLDVAAGEPLLLPQRFRQNRAWIELKKIWQTKKKVKGFRIKKIKGGYLVAIAGFITFLPFAKKKKRIANDRFTIDSFNPKRRDIVIIAADQTRT
Protein: Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1) (P63239)
Organism: Mus musculus (Mouse)
Function: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
Subcellular location: Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules.
Interaction partners:
- Pro-glucagon
- Pro-opiomelanocortin
- Insulin-1
- Insulin-2
- Receptor-interacting serine/threonine-protein kinase 3
- Appetite-regulating hormone
- Mixed lineage kinase domain-like protein
- Gastric inhibitory polypeptide
- Receptor-interacting serine/threonine-protein kinase 1
- Carboxypeptidase E
Sequence:
MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN
Protein: Trafficking protein particle complex subunit 9 (D3ZJK6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
Sequence:
MSVPDYMQCAEDHQTLLVVVQAVGIVSEENFFRIYKRICSVSQLSVRDSQRALFIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSPKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGDVAEQPRPDVAFYPNYDDCDSVEKRIEDFIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDALVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKTGARRLPGNSLPSEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACVKAVRVLAIQKRGMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFNKGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVTQSLENYTAKCPGTMEPITLPDGLTLPPVPFTKLPIVRCVKLLSLPTSLRPQKVKSLLGQSMSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGMITVNGYHTTVFGVFSDCLLDNLPGLKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSAGDEIATNVSVQLFNGETQQLAITLENIGLEPLEQLEVTSKLLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKAKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVESRPTNPSEGSKTGDLGHVKRQLFHAGKEEEEEEEKEGEEAAAADSSLMHVYYQRRTHEERSPCSSEQLLSLLLLELLEGPCQMYVALWVFPS
Protein: Small monomeric GTPase RhbA (EC 3.6.5.-) (GTP-binding protein Rheb homolog A) (GTP-binding protein rhbA) (E9R5S0)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q15382}; Lipid-anchor {ECO:0000250|UniProtKB:Q15382}; Cytoplasmic side {ECO:0000250|UniProtKB:Q15382}.
Interaction partners:
- GTPase activating protein
- Serine/threonine-protein kinase TOR
- Rho GTPase activator Rga, putative
- TORC1 growth control complex subunit Kog1, putative
- Nitrogen permease regulator 3
- Nitrogen permease regulator Npr2, putative
- Target of rapamycin complex subunit LST8
- Heat shock protein 90
- Puatative oxidoreductase
- GTP-binding protein
Sequence:
MPAAPKQRKIAIVGSRSVGKSSLTVRFVEHHFVESYYPTIENTFSRIIKYNGQDFATEIVDTAGQDEYSILNSKHFIGIHGYIIVYSVASRQSFDMVRVIRDKILNHLGADHVPLVVVGNKSDLKSEQRQVSLDEGRQLGEEFQCAFTEASARLDYNVTKAFDLMIGEIEKSQNPSQPAGGSKCILM
Protein: E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (Goliath-related E3 ubiquitin-protein ligase 1) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128) (Q9D304)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that catalyzes 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with 'Lys-48' linkages and COR1A with 'Lys-63' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm; sensitizes ectoderm to respond to neural-inducing signals (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8TEB7}. Endomembrane system {ECO:0000250|UniProtKB:Q8TEB7}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q8TEB7}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8TEB7}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8TEB7}. Note=Localized in an asymmetric perinuclear punctate manner. Localizes to the internal pool of the transferrin recycling endosomal pathway. Partially colocalized with the endoplasmic reticulum resident HSPA5, with Golgi resident STX5, and with the late endosomal GTPase RAB7A (By similarity). {ECO:0000250}.
Interaction partners:
- RING finger protein 148
- Ubiquitin thioesterase OTUB1
Sequence:
MGPPPGIGVYCRGGCGAARLLAWCFLLALSPHAPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVSGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLASERGASGAVIFNFPGTRNEVIPMSHPGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGKLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEASNTASPHEEDSRSETASSGYASVQGADEPPLEEHAQSANENLQLVNHEANSVAVDVVPHVDNPTFEEDETPDQEAAVREIKS
Protein: Light-harvesting complex-like protein OHP1, chloroplastic (High-light-induced protein) (AtHLIP) (One helix protein) (One helix protein 1) (Protein LIGHT-HARVESTING LIKE 2) (Protein PIGMENT DEFECTIVE 335) (O81208)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a photoprotective role in the thylakoid membrane in response to light stress (Probable). Involved in photosystems I (PSI) and II (PSII) core proteins function. Forms a trimeric complex with OHP2 and HCF244 that is required to promote PSII core subunit assembly. The trimeric complex forms a transient PSII reaction center-like complex with PsbA, PsbD, PsbE, PsbF and PsbI subunits in thylakoids for early assembly of PSII as well as PSII repair. The trimeric complex is required for the recruitment of ribosomes to the psbA mRNA during PSII biogenesis and repair. Forms an heterodimer with OHP1 that binds chlorophylls and carotenoids, and that may function in the delivery of pigments to the PsbA subunit of PSII.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:10794534, ECO:0000269|PubMed:29438089, ECO:0000269|PubMed:30397023}; Single-pass membrane protein {ECO:0000255}. Note=Associated with both photosystems I and II. {ECO:0000269|PubMed:10794534}.
Interaction partners:
- Light-harvesting complex-like protein OHP2, chloroplastic
- Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 244
- Photosystem II 22 kDa protein, chloroplastic
- Chlorophyll a-b binding protein CP26, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 5, chloroplastic
- Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 173
- Photosystem II stability/assembly factor HCF136
- Early light-induced protein 1
- Chlorophyll a-b binding protein
- Protein PAM68, chloroplastic
Sequence:
MSSSPLSSSLFHPLSTLSTHCHGRRQNLCFNRKQQPFVVRAAKLPEGVIVPKAQPKSQPAFLGFTQTAEIWNSRACMIGLIGTFIVELILNKGILELIGVEIGKGLDLPL
Protein: Probable pyridoxal 5'-phosphate synthase subunit SNO3 (EC 4.3.3.6) (PDX2 homolog 3) (Pdx2.3) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2) (P43544)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of a SNZ isoform.
Interaction partners:
- Pyridoxal 5'-phosphate synthase subunit SNZ1
- Probable pyridoxal 5'-phosphate synthase subunit SNZ3
- Probable pyridoxal 5'-phosphate synthase subunit SNZ2
- Pyridoxal 5'-phosphate synthase subunit SNO1
- Probable pyridoxal 5'-phosphate synthase subunit SNO2
- Pyridoxamine 5'-phosphate oxidase
- Putative pyridoxal kinase BUD16
- Uncharacterized protein YGR017W
- Putative pyridoxal kinase BUD17
- Isoamyl acetate-hydrolyzing esterase
Sequence:
MTVVIGVLALQGAFIEHVRHVEKCIVENRDFYEKKLSVMTVKDKNQLAQCDALIIPGGESTAMSLIAERTGFYDDLYAFVHNPSKVTWGTCAGLIYISQQLSNEAKLVKTLNLLKVKVKRNAFGRQAQSSTRICDFSNFIPHCNDFPATFIRAPVIEEVLDPEHVQVLYKLDGKDNGGQELIVAAKQKNNILATSFHPELAENDIRFHDWFIREFVLKNYSK
Protein: Modifier of protein aggregation 4 (Small EDRK-rich factor) (SERF) (Q9BKU8)
Organism: Caenorhabditis elegans
Function: Positive regulator of protein aggregation and age-related proteotoxicity. Induces conformational changes in aggregation-prone proteins, driving them into compact formations preceding the formation of aggregates.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:20723760}. Nucleus {ECO:0000269|PubMed:20723760}.
Interaction partners:
- Transcription factor lir-3
Sequence:
MTRGNQRDLAREKNQKKLADQKKRQGASGQDGNAGLSMDARMNRDADVMRIKQEKAAAKKEAEAAAAAANAKKVAKVDPLKM
Protein: Factor-induced gene 2 protein (Cell wall adhesin FIG2) (P25653)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for efficient mating. Plays a role in maintenance of cell wall integrity during mating. Important for mating cell projection shape and conjugation bridge diameter. Plays a role in cell fusion and nuclear migration.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:11027318, ECO:0000269|PubMed:9023939, ECO:0000269|PubMed:9456310}. Membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. Note=Periphery of the mating cells. Localized to the mating projection.
Interaction partners:
- A-agglutinin anchorage subunit
- AP-2 complex subunit mu
- Alpha-agglutinin
- Factor-induced gene 1 protein
- A-agglutinin-binding subunit
- Nuclear fusion protein FUS1
- Nuclear fusion protein FUS2
- Plasma membrane fusion protein PRM1
- Flocculation protein FLO11
Sequence:
MNSFASLGLIYSVVNLLTRVEAQIVFYQNSSTSLPVPTLVSTSIADFHESSSTGEVQYSSSYSYVQPSIDSFTSSSFLTSFEAPTETSSSYAVSSSLITSDTFSSYSDIFDEETSSLISTSAASSEKASSTLSSTAQPHRTSHSSSSFELPVTAPSSSSLPSSTSLTFTSVNPSQSWTSFNSEKSSALSSTIDFTSSEISGSTSPKSLESFDTTGTITSSYSPSPSSKNSNQTSLLSPLEPLSSSSGDLILSSTIQATTNDQTSKTIPTLVDATSSLPPTLRSSSMAPTSGSDSISHNFTSPPSKTSGNYDVLTSNSIDPSLFTTTSEYSSTQLSSLNRASKSETVNFTASIASTPFGTDSATSLIDPISSVGSTASSFVGISTANFSTQGNSNYVPESTASGSSQYQDWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYVTWCPLTQTKSQAIGVSSSISSVPQASSFSGSSILSSNSSTLAASNNVPESTASGSSQYQDWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYVTWCPLTQTKSQAIGISSSTISATQTSKPSSILTLGISTLQLSDATFKGTETINTHLMTESTSITEPTYFSGTSDSFYLCTSEVNLASSLSSYPNFSSSEGSTATITNSTVTFGSTSKYPSTSVSNPTEASQHVSSSVNSLTDFTSNSTETIAVISNIHKTSSNKDYSLTTTQLKTSGMQTLVLSTVTTTVNGAATEYTTWCPASSIAYTTSISYKTLVLTTEVCSHSECTPTVITSVTATSSTIPLLSTSSSTVLSSTVSEGAKNPAASEVTINTQVSATSEATSTSTQVSATSATATASESSTTSQVSTASETISTLGTQNFTTTGSLLFPALSTEMINTTVVSRKTLIISTEVCSHSKCVPTVITEVVTSKGTPSNGHSSQTLQTEAVEVTLSSHQTVTMSTEVCSNSICTPTVITSVQMRSTPFPYLTSSTSSSSLASTKKSSLEASSEMSTFSVSTQSLPLAFTSSEKRSTTSVSQWSNTVLTNTIMSSSSNVISTNEKPSSTTSPYNFSSGYSLPSSSTPSQYSLSTATTTINGIKTVYTTWCPLAEKSTVAASSQSSRSVDRFVSSSKPSSSLSQTSIQYTLSTATTTISGLKTVYTTWCPLTSKSTLGATTQTSSTAKVRITSASSATSTSISLSTSTESESSSGYLSKGVCSGTECTQDVPTQSSSPASTLAYSPSVSTSSSSSFSTTTASTLTSTHTSVPLLPSSSSISASSPSSTSLLSTSLPSPAFTSSTLPTATAVSSSTFIASSLPLSSKSSLSLSPVSSSILMSQFSSSSSSSSSLASLPSLSISPTVDTVSVLQPTTSIATLTCTDSQCQQEVSTICNGSNCDDVTSTATTPPSTVTDTMTCTGSECQKTTSSSCDGYSCKVSETYKSSATISACSGEGCQASATSELNSQYVTMTSVITPSAITTTSVEVHSTESTISITTVKPVTYTSSDTNGELITITSSSQTVIPSVTTIITRTKVAITSAPKPTTTTYVEQRLSSSGIATSFVAAASSTWITTPIVSTYAGSASKFLCSKFFMIMVMVINFI
Protein: Probable pectate lyase 5 (EC 4.2.2.2) (Q9FXD8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Putative pectinesterase/pectinesterase inhibitor 26
- At4g21108/At4g21108
- F8A5.27 protein
- At1g31410
- Subtilisin-like protease SBT2.6
- Myb family transcription factor PHL7
- Pectinesterase 4
- Exopolygalacturonase clone GBGE184
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- Pectin lyase superfamily protein
Sequence:
MRMTLVHLSLSLFSCLLLVLSPTFIASTPVSEPELVVQEVNEKINASRRNLGVLSCGTGNPIDDCWRCDPKWEKNRQRLADCAIGFGKHAIGGRDGKIYVVTDSSDKDVVNPKPGTLRHAVIQDEPLWIIFARDMVIKLKEELIMNSFKTIDGRGASVHIAGGACITVQYVTNIIIHGVNIHDCKRKGNAYVRDSPSHYGWRTASDGDAVSIFGGSHVWVDHCSLSNCADGLIDAIHGSTAITISNNYLSHHNKVMLLGHSDSYTRDKNMQVTIAFNHFGEGLVQRMPRCRHGYFHVVNNDYTHWQMYAIGGSAAPTINSQGNRFLAPNDHVFKEVTKYEDAPRSKWKKWNWRSEGDLFLNGAFFTPSGGGASSSYAKASSLSARPSSLVASVTSNAGALFCRKGSRC
Protein: FI03225p (Larval translucida, isoform A) (Larval translucida, isoform B) (Q9VS84)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Crossveinless 2
Sequence:
MTSLVYTVFHLASLQCSVRPEISPCTCETGKAWNHVELSCEKLESFNAVVDSLANKLNADTNIDLKITHSQLDDLEMRSFTDMNFNLYKLRMQWNSLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQEDFRGIQRVTNLILVSNIITRLDRGSFPKSLLILHLGRNQLESLNGSLHDLHNLESLFINANNITSLDDELPDGGQLRLLMAHNNRLERLPANMAGMHSLETVHIHCNQLRSFDRVLRNAVNLSEVMADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNSSLLPILKLKNANFSFNDIEEFSMAELHGLRSLKTLQLSSNRIQRLLPDPRGVQELMLVNLDLDNNRIDSLNGALAGLGNLRILNLAGNRLEHLQVGDFDGMIRLDILDLTGNQLAELKPLEMTLLPSLKILKVAYNNITKLEQDFKGLPVLCQANLTNNQISTISSELVTNTRCKNHNVPGKLEIHLDDNPIMCDVGLNELCRLMAVQEARIRGRSQCFENDQEVCTVLPMLYNVNLPIMVTNLKLTGREVPKPMVRVIVPSLIKANNELLPPLIATLGNPVLISTDLVNPVISPLPPPLLLATTTPPPPLPLPVESEVEKNESTTANPVPTNYTQETTTTTSTTTTTTTTETSSQVAPIEIITTTAPTTTTTSTTTPKPNETLPVIVELQDPNPPDTTVNQTALVPPVVLDPLQQDLERERERERERELERDLDHEAVAKTEYETVEYIPNLVQPPVGSDALTPPPSKANALEEDSESVHSNSVHAEYPHAAQSLQIPEEPPEE
Protein: Replication protein RepB (P13921)
Organism: Streptococcus agalactiae
Function: Is essential for plasmid replication. Nicks the positive strand at the plus origin of replication.
Interaction partners:
Sequence:
MAKEKARYFTFLLYPESIPSDWELKLETLGVPMAISPLHDKDKSSIKGQKYKKAHYHVLYIAKNPVTADSVRKKIKLLLGEKSLAMVQVVLNVENMYLYLTHESKDAIAKKKHVYDKADIKLINNFDIDRYVTLDVEEKTELFNVVVSLIRAYTLQNIFDLYDFIDENGETYGLTINLVNEVIAGKTGFMKLLFDGAYQRSKRGTKNEER
Protein: 2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic (EC 2.1.1.329) (Demethylphylloquinone methyltransferase) (Menaquinone biosynthesis methyltransferase ubiE-like protein) (Q3ED65)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the biosynthesis of phylloquinone (vitamin K1). Methyltransferase required for the conversion of 2-phytyl-1,4-beta-naphthoquinol to phylloquinol.
Subcellular location: Plastid, chloroplast {ECO:0000255|HAMAP-Rule:MF_03192, ECO:0000269|PubMed:17082184}.
Interaction partners:
- Alternative NAD
- Protein PHYLLO
- 2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic
- Probable NAD
- Probable NAD
- Probable NAD
- NAD
- 2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomal
- 1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal
- Cystinosin homolog
Sequence:
MAALLGIVSPVTFTGKHPVNSRSRRRTVVKCSNERRILFNRIAPVYDNLNDLLSLGQHRIWKNMAVSWSGAKKGDYVLDLCCGSGDLAFLLSEKVGSTGKVMGLDFSSEQLAVAATRQSLKARSCYKCIEWIEGDAIDLPFDDCEFDAVTMGYGLRNVVDRLRAMKEMYRVLKPGSRVSILDFNKSNQSVTTFMQGWMIDNVVVPVATVYDLAKEYEYLKYSINGYLTGEELETLALEAGFSSACHYEISGGFMGNLVAMR
Protein: CBP3-like protein (Q9USK6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Cytochrome b
- Assembly factor cbp4
- Cytochrome B pre-mRNA-processing protein 6
- Cytochrome b-c1 complex subunit 8
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Cytochrome b-c1 complex subunit 7
- ATP synthase subunit 9, mitochondrial
- Protein mss51
- Cytochrome c1, heme protein, mitochondrial
- Putative 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
Sequence:
MSRCCLNLPLRPAFVKQPVWGKSIYGPLRRRFSFSPINVINHSPSETKRRDPVEELRYKPLTPPQDPRKVAPPNSFLKKISLIYQKYISPKQNLYYEATGTARYMYFEAARQATPEKNSLGAFEFWYQKCEIPMTFQSWFQITQLHLWILHTRIRGLPKNEKVAFSQALTTRFFEDMELRIHKDYRINSNRISGMYLKDLFQQQTGAIFGYDQGMLGSDAVLATSVWRNLFVGRPDVDLVILETIVKFIRLNVYRLSCLSTDDFINGKGVHFVPPEESAQTNI
Protein: DNR protein (Transcriptional regulator Dnr) (Q51441)
Organism: Pseudomonas aeruginosa
Interaction partners:
Sequence:
MEFQRVHQQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLTPEGQEKILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLRQLQDNTPLALALLAKLSTRLHQRIDEIETLSLKNATHRVVRYLLTLAAHAPGENCRVEIPVAKQLVAGHLSIQPETFSRIMHRLGDEGIIHLDGREISILDRERLECFE
Protein: Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47) (P21956)
Organism: Mus musculus (Mouse)
Function: Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction (By similarity). Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization.
Subcellular location: Membrane {ECO:0000269|PubMed:2122462}; Peripheral membrane protein {ECO:0000269|PubMed:2122462}. Secreted {ECO:0000269|PubMed:2122462}. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:P79385}; Peripheral membrane protein {ECO:0000250|UniProtKB:P79385}. Note=Located in the acrosomal region of zona-pellucida bound sperm. {ECO:0000250|UniProtKB:P79385}.
Interaction partners:
- Growth arrest-specific protein 6
- Tyrosine-protein kinase receptor UFO
- Pro-epidermal growth factor
- Integrin beta-3
- Tyrosine-protein kinase receptor TYRO3
- Protein-glutamine gamma-glutamyltransferase 2
- Annexin A5
Sequence:
MQVSRVLAALCGMLLCASGLFAASGDFCDSSLCLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETETNYYNLDGEYMFTTAVPNTAVPTPAPTPDLSNNLASRCSTQLGMEGGAIADSQISASSVYMGFMGLQRWGPELARLYRTGIVNAWTASNYDSKPWIQVNLLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRKFEFIQDESGGDKEFLGNLDNNSLKVNMFNPTLEAQYIKLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQMSASSSYKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGSSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRLELLGC
Protein: Poly-beta-hydroxybutyrate synthase (Q8KXD5)
Organism: Azospirillum brasilense
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MVGDLGVDDAQFTQRLLDVLKLPFQVGDAAAGDALHEAHLLLLDLVRVVEGEEFLSRQASDGVGAKNPDPMGVGHAFLEMTTRMMADPAKLMKAQMTLWQDYLTLWQRTTQRFFGQDAQPVIAPAKDDRRFKDSAWDENTLFDFIKQSYLLSARWMQSTVNEVDGLDDHTAKKVDFYTRQFVDAMAPSNFVMTNPEVLRTTIETGGENLVKGLEHLLKDLERGKGELRISMTDYDAFQVGKNIAVTPGKVVFQTDLMQLIQYTPTTPEVNKRPLMIVPPWINKYYILDLREKNSFIKWAVDQGHSVFVLSWVNPDEKLAQKGFEDYMFEGVLAALDAIEKVTGEKDVNAIGYCLGGTLLASTLSYMAAKKDDRIKSATFFTTMLDFTEAGELSVFIDEEQLTMIESQMAQQGYLDGSKMATTFNMLRANDLIWSFVVNNYLLGKDPFPFDLLYWNSDSTRMPAAMHSFYLRNMYQKNLLAQPGAVTLGGVPIDLRKVKTPSFFLSAREDHIAPWKSTYMGAHLFSGPVKFVLAASGHIAGVVNPPAAGKYCYWTNAKLPKASDDWLASSEQTPGSWWPEWNNWVSTFSEGKVPARNPEKGGLPVLEDAPGSYAKVRIV
Protein: Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (hSGLT4) (Solute carrier family 5 member 9) (Q2M3M2)
Organism: Homo sapiens (Human)
Function: Involved in sodium-dependent transport of D-mannose, D-glucose and D-fructose.
Subcellular location: Cell membrane {ECO:0000305|PubMed:15607332}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSKELAAMGPGASGDGVRTETAPHIALDSRVGLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIPEEQLTRLTWWTRNCPLSELEKEAHESTPEISERPAGECPAGGGAAENSSLGQEQPEAPSRSWGKLLWSWFCGLSGTPEQALSPAEKAALEQKLTSIEEEPLWRHVCNINAVLLLAINIFLWGYFA
Protein: DNA repair endonuclease XPF (EC 3.1.-.-) (Protein meiotic 9) (Q24087)
Organism: Drosophila melanogaster (Fruit fly)
Function: Implicated in recombination events during meiosis, mostly in meiotic exchange. May directly resolve Holliday junctions within recombination intermediates leading to DNA exchange. Also required for the repair of mismatches within meiotic heteroduplex DNA and for nucleotide excision repair.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DNA excision repair protein ERCC-1
- Structure-specific endonuclease subunit SLX4
- Crossover junction endonuclease MUS81
- RecQ-like DNA helicase Blm
- DNA repair protein complementing XP-A cells homolog
- FI23547p1
- Protein hold'em
- Structure-specific endonuclease subunit SLX1 homolog
- Serine/threonine-protein kinase ATR
- DNA repair protein complementing XP-C cells homolog
Sequence:
MADSCAENAAKGTENERPKEVEASADTVPQVEEGVEEYLKRKNMVLLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSGNLVLVINSSDWEEQYYKSKIEPKYVHEVASTATERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIESCQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPWKIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDCIWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEYALSNSGWTLLDAAEQIFKLSRQRVFNGQQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQPKVLILCQDARTCHQLKQYLTQGGPRFLLQQALQHEVPVGKLSDNYAKESQTRSAPPKNVSSNKELRREEVSGSQPPLAGMDELAQLLSESETEGQHFEESYMLTMTQPVEVGPAAIDIKPDPDVSIFETIPELEQFDVTAALASVPHQPYICLQTFKTEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILLIEFDQNKPFHLQGKFMLSQQTSMANADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLGKPEPDPQTAAALGSDEPTAGEQLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQESAKLLYDILHVAHLPEKDEVTGSTALLAASKQFGAGSHNRFRMAAAASRRGRR