wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial 15S rRNA processing factor ppr3 (Pentatricopeptide repeat-containing protein 3) (O42955)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:21727087}.
Interaction partners:
- Small ribosomal subunit protein uS2m
- Pentatricopeptide repeat-containing protein 6
- Uncharacterized protein C106.19
- Mitochondrial cox1 translation regulator ppr4
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS17m
- Small ribosomal subunit protein uS4m
- Small ribosomal subunit protein uS8m
- Small ribosomal subunit protein mS45
Sequence:
MLNKCSGSLTLLAVRRFCGPCRRLHYHKDNPNNINIAKNLLNNNIQARCSTNEASWKLAQKELDLKIREYEQKLKDVKLNDINKKSPLNIPDEVWTKFISEVNSYDKEKENHLSTGNHELRRTTPLKIGPLLLTRIGLLKSKNTASNNYSVDHIVSNLANDNTLLNRQVSTEEWNSHLRHLLNIPKCFLGVDIVEIVNFFNYLPQTVISKSSLEIWKAVEESGMKVMPDLLVLLMESTNASGDFRKTVQLYHLYQKSNAPPNGLVYQSYAIALSSLGKHKDLVALYSEQKSVSITPSKDFLNACIKAFSRTKEFTKAWEVFNFMKFTATSISPSAETYGLMIQICSSQYNPEKALDLYNEMKLRPIDPLTPTTFVINNLIHALATDVRFQTVAFSLLQDLSHYGLRPNHSTLYELIRLIAYSGKLDYMKDILDNFWVRQKLLPSILKVEQIFHFIFRALISAEVQTSSVTPDYTHFKEEVRKIIDSSKEPLIPFLKRSTLTENDLFLNAIYTFEYAKRKFPEALNSRLVTDFLNIFLERGSVQLFKEIYQLEFREMSTMEGSSMKVAKITLTYIYAIKLALLFNDFEFGYAAWQEYWHCKIHKLLPKEDASYEQKVVLLTLSLLSKNKHTSLARSLLLSHLDKGWTWNKHSLGFMRKMCSVMNDQATVYLIDSITNEIGINQRFTRK
Protein: Potassium transporter 13 (AtKT5) (AtPOT13) (Q8LPL8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable potassium transporter.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- MATH domain and coiled-coil domain-containing protein At3g58220
- Protein PAL OF QUIRKY
- AT4G01090 protein
- PRA1 family protein F1
- WAT1-related protein At5g64700
- Chloride channel protein CLC-c
Sequence:
MFHVEEESSGGDGSEIDEEFGGDDSTTSLSRWVFDEKDDYEVNEDYDDDGYDEHNHPEMDSDEEDDNVEQRLIRTSPAVDSFDVDALEIPGTQKNEIEDTGIGKKLILALQTLGVVFGDIGTSPLYTFTVMFRRSPINDKEDIIGALSLVIYTLILIPLVKYVHFVLWANDDGEGGTFALYSLICRHANVSLIPNQLPSDARISGFGLKVPSPELERSLIIKERLEASMALKKLLLILVLAGTAMVIADAVVTPAMSVMSAIGGLKVGVGVIEQDQVVVISVSFLVILFSVQKYGTSKLGLVLGPALLLWFFCLAGIGIYNLVKYDSSVFKAFNPAYIYFFFKRNSVNAWYALGGCVLCATGSEAMFADLSYFSVHSIQLTFILLVLPCLLLGYLGQAAYLSENFSAAGDAFFSSVPSSLFWPVFLISNVAALIASRAMTTATFTCIKQSIALGCFPRLKIIHTSKKFIGQIYIPVLNWSLLVVCLIVVCSTSNIFAIGNAYGIAELGIMMTTTILVTLIMLLIWQTNIIVVSMFAIVSLIVELVFFSSVCSSVADGSWIILVFATIMFLIMFVWNYGSKLKYETEVQKKLPMDLLRELGSNLGTIRAPGIGLLYNELAKGVPAIFGHFLTTLPAIHSMVIFVCIKYVPVPSVPQTERFLFRRVCPRSYHLFRCVARYGYKDVRKESHQAFEQILIESLEKFIRKEAQERALESDGDHNDTDSEDDTTLSRVLIAPNGSVYSLGVPLLAEHMNSSNKRPMERRKASIDFGAGPSSALDVEQSLEKELSFIHKAKESGVVYLLGHGDIRATKDSWFLKKLVINYLYAFLRKNSRRGITNLSVPHTHLMQVGMTYMV
Protein: Phosphoglycerate mutase 3 (PGAM 3) (EC 5.4.2.11) (BPG-dependent PGAM 3) (MPGM 3) (Phosphoglyceromutase 3) (Q12326)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Could be non-functional.
Interaction partners:
- Phosphoglycerate mutase 1
- Phosphoglycerate mutase 2
- Enolase 2
- Phosphoglycerate kinase
- Broad-specificity phosphatase YOR283W
- Enolase 1
- Enolase-related protein 1
- Enolase-related protein 3
- Fructose-bisphosphate aldolase
- Glucose-6-phosphate isomerase
Sequence:
MTVTDTFKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFCDSNNISLPQIGYTSRLIRTQQTMDVILEELGLKHTNYVITTNTNIKEELQDTRFEGSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNLNLEMVQEENDQGSSTGYDFKEPNRHLKYGPEEKANERLPESESLCEVVVRLKPFLNNVVLSTANKISQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVRKFYLDPESAKVNAQMVRDEGFEKNP
Protein: Replication protein A2 (Q5TEJ0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
LEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE
Protein: Large ribosomal subunit protein eL15 (60S ribosomal protein L15) (Q9CZM2)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:36517592}.
Interaction partners:
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein uS8
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein eS24
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein eS12
Sequence:
MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR
Protein: Envelope glycoprotein G (gG) (P28967)
Organism: Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus)
Function: Chemokine-binding protein that inhibits neutrophils' chemotaxis.
Subcellular location: Virion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLTVLAALSLLSLLTSATGRLAPDELCYAEPRRTGSPPNTQPERPPVIFEPPTIAIKAESKGCELILLDPPIDVSYRREDKVNASIAWFFDFGACRMPIAYREYYGCIGNAVPSPETCDAYSFTLIRTEGIVEFTIVNMSLLFQPGIYDSGNFIYSVLLDYHIFTGRVTLEVEKDTNYPCGMIHGLTAYGNINVDETMDNASPHPRAVGCFPEPIDNEAWANVTFTELGIPDPNSFLDDEGDYPNISDCHSWESYTYPNTLRQATGPQTLLVGAVGLRILAQAWKFVGDETYDTIRAEAKNLETHVPSSAAESSLENQSTQEESNSPEVAHLRSVNSDDSTHTGGASNGIQDCDSQLKTVYACLALIGLGTCAMIGLIVYICVLRSKLSSRNFSRAQNVKHRNYQRLEYVA
Protein: MbtH-like domain-containing protein (Q9I169)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Pyoverdine synthetase D
- Probable non-ribosomal peptide synthetase
- Pyochelin synthetase PchF
- Probable thioesterase
- Pyochelin synthetase PchE
- PvdL
- PvdJ
- Probable non-ribosomal peptide synthetase
- L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH
- Pyochelin synthase PchD
Sequence:
MTSVFDRDDIQFQVVVNHEEQYSIWPEYKEIPQGWRAAGKSGLKKDCLAYIEEVWTDMRPLSLRQHMDKAAG
Protein: E3 ubiquitin ligase Rnf157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase Rnf157) (Q3TEL6)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons. Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical. May act as a scaffold molecule to regulate this process. Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:M0R5D6}.
Interaction partners:
- Modulator of smoothened protein
Sequence:
MGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDSTHPEGYLFGENSDLNFLGNRPVAFPYAAPPPQEPVKTLRSLINIRKDTLRLVKCAEEVKSHGEEAGKAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVHYKRGVFQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVLLGTFEKHPDGTFCVKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDDVSDNSAECVVCLSDVRDTLILPCRHLCLCNTCADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPSSFNPIISSQTSDSEEHSSSENIPPGYEVVSLLEALNGPLTSSPAVPPLHVLGDGHLSGMLPSYGSDGYLPPVRTLSPLDRLSDCNNQGLKLKKSLSKSISQNSSVLHEEEDERSCSESDTQLSQRLSVQHPEEGPDVTPESENLTLSSSGAVDQSSCTGTPLSSTISSPEDPASSSLAQSVMSMASSQISTDTVSSMSGSYIAPGTEEEGEALPSPRAASRAPSEGEETPAESPDSNFAGLPAGEQDAEGNDIIEEEDRSPVREDGQRTCAFLGMECDNNNDFDVASVKALDNKLCSEVCLPGEWQCAEHELGGRRPSARPRSPRGGLGKEASAFRIETVALPGTYV
Protein: Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog) (Q8BR65)
Organism: Mus musculus (Mouse)
Function: Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9H7L9}.
Interaction partners:
- Paired amphipathic helix protein Sin3a
- Histone deacetylase complex subunit SAP30
- Histone-binding protein RBBP4
- Histone deacetylase complex subunit SAP18
- Histone deacetylase 1
- Paired amphipathic helix protein Sin3b
- Histone deacetylase 2
- Histone-binding protein RBBP7
- AT-rich interactive domain-containing protein 4B
- Inhibitor of growth protein 1
Sequence:
MSAAGLLAPAPAPAAAPAAPEYYPEDEEELESAEDDERSCRGRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYRERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYVGQLQRGLFVIRRRSAA
Protein: Neural cell adhesion molecule 2 (Q59E14)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- MIP16756p
- FI04444p
Sequence:
MDTLIALCSLLLLLLSQNAAILGQLDSTSSGGSGTGGAPPDRPPTPPLSLQPSTPSITHFVNESFIIFCQTVQKDIDTKWRDPRGQTRENTKGRVHIEKKTTGLLALVFEHIALEDRGNWTCEVNGNRNGNRNVNVEREFLASFELLVNQKISFGKTEQVQSVREGRDAMVNCFVEGMPAPEVSWLYNGEYINTVNSTKHNRLSNGLYIRNVSQADAGEYTCRAMRITPTFSDSDQITILLRIQHKPHWFFNETLPVQYAYVGGAVNLSCDAMGEPPPSFTWLHNNKGIVGFNHRIFVADYGATLQLQMKNASQFGDYKCKVANPLGMLERVIKLRPGPKPLGPRRFQLKKLYTNGFELDIQTPRMSNVSDEMQIYGYRVAYMSDTEFKFSAGNWSYAKQRDFSFHGGKHFIIPHLETNTTYLMRAASRNLAGLSDWSPVKVFTTAAGCSWSPWLYPSYGLILALIWT
Protein: Os06g0724800 protein (cDNA clone:001-116-H12, full insert sequence) (Q5Z988)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MELDEQAFLEELFSLRRDAWEYNAMGDFFSPACAAMDGFQERHQSTTTVSVLPTFTASYEQPPPAPAAGFDCLSEVYGNAAAAFGPNAGGGGGEYGGGGDMGFLDVVEPKASMVVDGGGLGVCKVEPGLQAEGGFSAAAAAPASKKKRVEGMPSKNLMAERRRRKRLNDRLSMLRSVVPKISKVYRVLSESFCVAIGIASAREMRLDDVCVCE
Protein: Amphiregulin (AR) (Colorectum cell-derived growth factor) (CRDGF) (P15514)
Organism: Homo sapiens (Human)
Function: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Subcellular location: Membrane; Single-pass membrane protein.
Interaction partners:
- Epidermal growth factor receptor
- Pro-epidermal growth factor
- Proepiregulin
- Receptor tyrosine-protein kinase erbB-3
- Receptor tyrosine-protein kinase erbB-4
- Probetacellulin
- Protransforming growth factor alpha
- Receptor tyrosine-protein kinase erbB-2
- Intercellular adhesion molecule 1
- Epigen
Sequence:
MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKKLRQENGNVHAIA
Protein: Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2) (B2RXH8)
Organism: Homo sapiens (Human)
Function: May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs.
Subcellular location: Nucleus {ECO:0000250}. Note=Component of ribonucleosomes. {ECO:0000250}.
Interaction partners:
- RNA-binding Raly-like protein
Sequence:
MASNVTNKMDPHSVNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVAVINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYGFQRDYYDGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEQSKQEVEVKNAKSEEEQSSSSMKKDETHVKMESEGGAEDSAEEGDPLDDDDNEDQGDNQLHLIKNNEKDAEEGEDNRDSTNGQDDS
Protein: DNA replication protein repEA (DNA-binding protein dbpB) (P32284)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Involved in T4 DNA replication. Binds to ssDNA.
Interaction partners:
Sequence:
MVILLHKFQLDELIYIVLAQGYHQIPEYVRFQFPLYAHKDIHLYMKKLVL
Protein: Thioredoxin M3, chloroplastic (AtTrxm3) (Protein GFP ARRESTED TRAFFICKING 1) (Q9SEU7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Thiol-disulfide oxidoreductase required for maintaining symplastic permeability in the meristem. Involved in redox regulation of callose deposition, plasmodesmata cell-to-cell communication and meristem maintenance.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:19218459, ECO:0000269|PubMed:19259774}.
Interaction partners:
- Thioredoxin F2, chloroplastic
- Thioredoxin F1, chloroplastic
- Thioredoxin H5
- Myosin-2
- 2-Cys peroxiredoxin BAS1-like, chloroplastic
Sequence:
MAISSSSSSICFNPTRFHTARHISSPSRLFPVTSFSPRSLRFSDRRSLLSSSASRLRLSPLCVRDSRAAEVTQRSWEDSVLKSETPVLVEFYTSWCGPCRMVHRIIDEIAGDYAGKLNCYLLNADNDLPVAEEYEIKAVPVVLLFKNGEKRESIMGTMPKEFYISAIERVLNS
Protein: Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) (Q9I262)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Cyanate hydratase
- Probable sulfate transporter
- Carbonic anhydrase
- Carbonic anhydrase
- Transcriptional regulator CynR
- Serine/threonine transporter SstT
- Probable aldehyde dehydrogenase
Sequence:
MRDIIDGFLRFQRDAYPARSQLFKSLATRQAPKALFIACSDSRVVPELLTQREPGELFVIRNAGNIVPGYGPQPGGVSASVEYAVAVLGVGDIVVCGHSDCGAMGAIASCACLDQLPAVAGWLHHAEAARAMNSAHEHASEAARLDALVRHNVIAQLANLRTHPCVARALEQGRLNLHGWVYDIESGRIDALDGASRRFVSLAEHPEVRAVGGEPGQAVA
Protein: C6 finger domain protein, putative (AFU_orthologue AFUA_1G14280) (Q5BFB4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MDSRTMTAETPGKRPRSDSGEFPPIASKVPKTHSNHLQINYLARQYADNLPLVSLDDTMPAIIHLIGEYDGVLQRHESIAGNLGACPLGPILIKRFERLFDGPPRVLKSHGKDTPNITWLDVVEFAKNKPEQFNLEKTRNGVRVCQFYTKQSRVEISEEDFVLIASGMPQKMIPPQPIIEDEEKELGALEILEKNLQSIIQVADQVSARARQLNHRLKNRRTAIVTRRENDVNLHNSRASQPLSQSQHLPQQRSMSPAWRDANGVPHSSLNSNGNGNGASNAQSPSTGFVAVNASRPGGEAPPEENLLSSQFLFSHSNTDNVTIINGTSIKGASPTTRAELMKKFFTTQDRQVRGSYEEAAAAAAAAAGSSNRQSSRPRPRASEGGDYNVYAPTPATVAIPNTPTSLLPPPKSHHHEKDDGGPFKIEMVARMEELQRGERIMPPCDRCRRLHMDCLKNLTACMGCTKKHAKCSWRDVKEEELREGRRADRGPVEEPHSKDTTASPSTAPASEQVPPSTAVATPASAPAPLPTSLPGSATAASDPERPREGALDVMVRRESAPIAAPVSRPSAVREVSPRRAVSEIHNSHGHSYRHNQSDRRYSFNRNNEPNRDDDGPDALSQAIMDTYNAAAAKGTVHEVSNERERDMERDQDRDRKLVRA
Protein: Probable serine/threonine-protein kinase At1g54610 (EC 2.7.11.1) (Q9ZVM9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGCVFGREAATTTTAEAKQAKSSKASSGVVVVGESSVTKSNGVIADDVEKKKNEEANGDKERKSSKGDRRRSTKPNPRLSNPSKHWRGEQVAAGWPSWLSDACGEALNGWVPRKADTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIYKPREPYKRSIRETFKDFPPSSLPLIDALLSIEPEDRQTASAALKSEFFTSEPYACEPADLPKYPPSKEIDAKRRDEETRRQRAASKAQGDGARKNRHRDRSNRALPAPEANAELQSNVDRRRLITHANAKSKSEKFPPPHQDGGAMGVPLGASQHIDPTFIPRDMVPSFTSSSFNFSKDEPPTQVQTWSGPLGHPITGVSRKKKDNTKSSKGKRAVVA
Protein: Protein XRP2 (Q9EPK2)
Organism: Mus musculus (Mouse)
Function: Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O75695}; Lipid-anchor {ECO:0000250|UniProtKB:O75695}; Cytoplasmic side {ECO:0000250|UniProtKB:O75695}. Cell projection, cilium {ECO:0000250|UniProtKB:O75695}. Note=Detected predominantly at the plasma membrane of rod and cone photoreceptors. Not detected in the nucleus. {ECO:0000250|UniProtKB:O75695}.
Interaction partners:
- ADP-ribosylation factor-like protein 3
- Protein unc-119 homolog B
Sequence:
MGCCFTKRRKSEKAEGEEEQPKLYSWDQREKVDPKDYMFSGLKDETVGRLPGKVAGQQFVIQDCENCNIYIFDHSATITIDDCTNCVIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIESSTNIKFGCFQWYYPELAAQFKDAGLSIFNNIWSHVHDFTPVSGELNWSLLPENAVVQDYVPIPMTEEFKAVRISTEANRSIVPVSRGQRQKYSDESCLVVLFADDYTTANARKLIDEMVGKGFSLVQTKEMSMKTEDAQRVFQEKASDFLLLLNKGPVIALEFNGDDAVQECHLIVNGMFNGTKMFVSEKKETASGDVDSFYNFAEIQMGI
Protein: Protocadherin gamma subfamily C, 4 (A0A0A6YVS5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAAMPSTQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Protein: Thiohydroximate-O-sulfate sulfur/sulfate-lyase (nitrile-forming) NSP3 (EC 4.8.1.5) (Jacalin-related lectin 27) (Nitrile-specifier protein 3) (AtNSP3) (O04318)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes simple nitriles, but not epithionitrile or thiocyanate formation. Converts allylglucosinolate and benzylglucosinolate to their corresponding simple nitriles in the presence of myrosinase.
Interaction partners:
- UPF0235 protein At5g63440
- Beta-glucosidase 19
- Beta-glucosidase 23
- Probable cysteine protease RD21C
- Probable cysteine protease RD21B
- Cysteine proteinase RD21A
- At1g09850
- Beta-glucosidase 33
- Beta-glucosidase 26, peroxisomal
- Peroxidase 19
Sequence:
MAQKLVAQGGETGDVWDDGVYDNVTKVYVGQGQYGIAFVKFEYANGSEVVVGDEHGEKTELGVEEFEIDSDDYIVYVEGYREKVSDMTSEMITFLSFKTSKGKTSQPIVKKPGVKFVLHGGKIVGFHGRSTDVLHSLGAYVSLPSTPKLLGNWIKVEQNGEGPGLRCSHGIAQVGNKIYSFGGELIPNQPIDKHLYVFDLETRTWSIAPATGDVPHLSCLGVRMVSVGSTLYTFGGRDFSRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVGAMDRIKTLDSYNIVDKTWFHCSNPGDSFSIRGGAGLEVVQGKVWIVYGFNGCEVDDVHFYDPAEDKWTQVETFGVKPNERSVFASAAIGKHIVIFGGEIAMDPRAHVGPGQLIDGTFALDTETLQWERLDKFEGTPSSRGWTASTTGTIDGKKGLVMHGGKAPTNDRFDDLFFYGIDSV
Protein: Microtubule-associated protein (Q381G6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDRKLVEMQAVISRREAEFRKQNMDLFTELLGEMRTEDGLCEKNSKELQYKQKELAKQRAEIEKAEKDVKAKLDKVKLTRSRLAEQMSEIKEKLETLRKWGPADHASPLGLLPAGATAAAPENGSNGPAQTS
Protein: Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC) (O88656)
Organism: Rattus norvegicus (Rat)
Function: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O15143}. Nucleus {ECO:0000250|UniProtKB:O15143}.
Interaction partners:
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 2
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2/3 complex subunit 5
- Actin-related protein 2
- Actin-related protein 3
- Actin-related protein 2/3 complex subunit 5-like protein
- Actin nucleation-promoting factor WAS
- Actin nucleation-promoting factor WASL
- Actin related protein 3B
Sequence:
MAYHSFLVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWNKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSAGGSRVAWVSHDSTVCLVDAEKKMAVATLASETLPLLAITFITENSLVAAGHDCFPVLFTYDNAAGTLSFGGRLDVPKQNSQRGLTARERFQNLDKKASSEGGAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIR
Protein: Homeobox protein MSX-2 (Homeobox protein Hox-8-1) (P52953)
Organism: Rattus norvegicus (Rat)
Function: Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Msh homeobox 1.
- Runt-related transcription factor 2
- Msh homeobox 3
- Osteocalcin
- Bone morphogenetic protein 2
- Bone morphogenetic protein 4
Sequence:
MSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSGFSLPFPINSPLQAASIYSASYPFHRPVLPIPPVGLYATPVGYGMYHLS
Protein: Salty dog, isoform C (A0A0B4LHY2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MASSVSNLASTVATATTATLEDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVLVAILGTSNTGGITNVLENAAEGGRFDFSFGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSEAKANATMKLVIVVMGAYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAINKNVTNVGTTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYSPFVRSMLNKPSPVLELEELPLKTPLSEEQIKEKENGSATEA
Protein: Nucleoporin 54kDa S homeolog isoform X2 (Nup54) (K9ZTJ6)
Organism: Xenopus laevis (African clawed frog)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Nuclear pore complex protein
- Nuclear pore complex protein Nup93
- Nuclear pore complex protein Nup155
- Uncharacterized protein.
- Nuclear pore glycoprotein p62
- Uncharacterized protein.
- Uncharacterized protein.
- Nuclear pore complex protein Nup153
- Nucleoporin NUP188
- Nuclear pore complex protein Nup85
Sequence:
MAFNFGATTGTPANQGTTGFSLGTFTPKTTTSGFGFGTTTTTAPTGFGGGFGGFGATTTASTGPAFSFTTPANTTSGLFGATQNKGFGFGTGFGSTTTSTGLGTGLGTGLGFTGFNTSQQQQQQSVLGAGLFNQSFQSTPQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKGFFMNNTPPVEFTQENPFCRFKAVGFSYIPNNKDEDGLISLIFNKKESDIRGQQQQLVESLHKVLGGHQTLTVNVEGVKTKADNQTEVIIYVVERSPNGTSRRVGASALFSYFEQAHIKANMQQLGVTGAMAQTELSPVQIKQLIQNPLSGVDPIIWEQAKVDNPDPERLIPVPMIGFKELLRRLEVQDQMTKQHQSRLDIISEDIGELQKNQTTTMAKIGQYKRKLMELSHRVLQVLIKQEIQRKSGFAIQAEEEQLRVQLDTIQSELNAPTQFKGRLNELMSQIRMQNHFGAVRSEEKYYVDADLLREIKQHLKQQQEGVSHLISIIKDNHEDIKLIEQGLNDNLHMRTGFLS
Protein: Agenet domain-containing protein (F4KEA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MVRRAGSERPSMEEGCEFEIYNKKDPRSYHLTFRSRNILEDVWYKAIVEAKPPKSPKSKRSVLCVRLLKDDFSNSIPIKIGSIVEADYKDAWVTGFVVKEIDVGKCLVCFDSIPDVILFERKLLRPHLQWLDDSGYTFWDMVSKHYRKFLRRLAEEPMFSPGTMVEVSSKINEGEVVWVPSMVIKEFKEDDEYKYIVKDKSFSCEGKKARPNKTVDLSSLRPIPVSVDEYQLEENVEVFLDGMGWRHGRVMGSQERAIGTLSQKWYFVRLESTKKQLTFKQSDLRPLKVWEDGVWKVLQTRELSFTQGSGDKTGDSVRNANESDPPLTPPPGIITPPLKQIEAGTQRKALSKKTLPRNQNGSGNDSTLENENSEDNNRKRKREENLGCVASVEQDKPKDTTMVLPFEKKLRIWETLESMEVFKTVPQSPHFSPLLVESREDSREMSAVGMMLTFFGLLDEVKALQHNDPISFFISLTNSFAELEKHGFNVKAPQSRINKLLSLRDRQSKKTEELKDAEKVTAEKESVKAENKRKILELQRLNEEMDKEIAQSKSCAAKIVQQLDDVKLEFLATASAPW