wanglab/gogpt-training-data huggingface dataset:
Protein: Transmembrane BAX inhibitor motif containing 1 (C9JDV0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWD
Protein: Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (O59705)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for normal Golgi morphology and function.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:16823372}; Peripheral membrane protein {ECO:0000269|PubMed:16823372}; Cytoplasmic side {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 8
- Vacuolar protein sorting-associated protein 52
- Vacuolar protein sorting-associated protein 54
- Vacuolar protein sorting-associated protein 53
- Protein transport protein sec20
- Conserved oligomeric Golgi complex subunit 5
Sequence:
MTEKDADSGSDLVDAFLSDAYLNTEELRKDGPFSPDEFLVSKRFLGLDGLVNELSRLFEQVNNELMLLVKDNYQDFVHLGSRMKSGNTKVSTLISSIHRSEEQLKNSKQSLIGHSTEIQNNLKHKQDVENEKLIASNLLLLDQILKFLKSNDSSHPLWLESLNNAQRLCDTYKDHPWVQSISPTLINYIKH
Protein: At4g09040 (RNA-binding (RRM/RBD/RNP motifs) family protein) (Q6NPL0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- Putative U3 small nucleolar ribonucleoprotein
- Periodic tryptophan protein 2
- rRNA processing protein-like protein
- Putative WD-repeat membrane protein
- Bystin
- Pescadillo homolog
- Ribosome biogenesis protein WDR12 homolog
- Pumilio homolog 23
- Ribosome biogenesis protein BOP1 homolog
Sequence:
MALLRLPGISLQILGHKSNQKNPNPNVAFTNHSLSLSTPSLCRLHRHATFPDSIPAKSRNLTSYFSTTTQEPVLESSSSSSSAPEVVEEEISKTRLIAQNVPWTSTPEDIRSLFEKYGSVIDIEMSMHKKERNRGLVFIEMASPEEAATALKSLESCEYEGRRLKVDYAKTKKKKTYAPRETPSPVPTFNLFVANLAFEARAKHLKEFFDADTGNVVSTEVIFHENPRRSSGYGFVSFKTKKQAEAALIEFQGKDFLGRPIRLAKSKQFVKLQAKEGLQPPEEEAEEEPSQSETMTQEHETPAA
Protein: Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP-responsive element modulator in testis) (Activator of CREM in testis) (Q9WTX7)
Organism: Mus musculus (Mouse)
Function: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:10086359}. Note=Nuclei of round and elongated spermatids.
Interaction partners:
- cAMP-responsive element modulator
Sequence:
MTSSQFDCQYCTSSLIGKKYVLKDDNLYCISCYDRIFSNYCEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKDDRLLCTDCYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFRDQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHLYAKKCAACTKPITGLRGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTHNMEILCRKCGSGADTDA
Protein: NADH-dependent fumarate reductase, putative (Q38BN4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Electron transfer protein, putative
- Succinate dehydrogenase, putative
- Reiske iron-sulfur protein, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Succinate dehydrogenase assembly factor 2, mitochondrial
- Citrate synthase
- Succinate--CoA ligase subunit beta, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
Sequence:
MLSTKQLLLRATSALVAGSSGVARDSPSLVGDPCDSVSPMRVVWGRFFKSLAPPAPSVVSCQKRFTSHGADGISSASIVVTDPEAAAKKRDRMARELLSSNSGLCQEDEPTIINLKGLEHTIPYRLAVVLCNSRSTGEFEAKAAEILRKAFHMVDYSLNCFNPESELSRVNSLPVGEKHQMSEDLRHVMECTISVHHSSGMGFDPAAGPIISRLRGAMRDHNDMSDISVTEAEVELFSLAQSFDVDLEEGTIARKHSEARLDLGGVNKGYTVDYVVDHLRAAGMPNVLFEWGGDIRASGRNIKGNLWAVAIKRPPSVEEVIRRAKGKMLKMGEEEQEEKDDDSPSLLHVVELDDEALCTSGDYENVLYHPKHGVAGSIFDWQRRGLLSPEEGALAQVSVKCYSAMYADALATVCLVKRDAVRIRYLLEGWRYVRSRVTNYFAYTRQGERLAHMHEIAQETRELREIRIAGSLPSRIVIVGGGLAGLSAAIEAASCGAQVILMEKEGRIGGNSAKATSGINGWGTRTQAKSDILDGGKYFERDTFLSGVGGTTDPALVKVLSVKSGDAIGWLTSLGVPLSVLSQLGGHSFKRTHRAPDKTDGTPLPIGHTIMRTLEDHIRNNLSERVTIMTHVSVTELLHETDTTPDGASEVRVTGVRYRDLSDVDGQPSKLLADAVVLATGGFSNDREENSLLCKYAPHLASFPTTNGPWATGDGVKLATSVGAKLVDMDKVQLHPTGLIDPKDPANTTKILGPEALRGSGGILLNKQGKRFVNELDLRSVVSKAINTQGNEYPGSGGCYFAYCVLNEDATNLFGGGALGFYGKKLGLFQRAETVEELAKLIGCDEGELRDTLEKYETCSKAKVACPVTGKVVFPCVVGTRGPYNVAFVTPSIHYTMGGCLISPAAEVLQEYKGLNILENHRPIRCLFGAGEVTGGVHGGNRLGGNSLLECVVFGKIAGDRAATILQKREIALSKTSWTSVVVRESRSGEQFGTGSRVLRFNLPGALQRTGLNLGEFVAIRGEWDGQQLVGYFSPITLPEDLGTISLLVRADKGTLKEWICALRPGDSVEIKACGGLRIDQDPVKKCLLFRNRPITRFALVAAGTGVAPMLQVIRAALKKPYVDTLESIRLIYAAEEYDTLTYRSILQRFAEEFPDKFVCNFVLNNPPEGWTGGVGFVNKKSLQKVLQPPSSEPLIVVCGPPVMQRDVKNELLSMGYDKELVHTVDGESGTL
Protein: Ribonuclease H (RNase H) (EC 3.1.26.4) (Q04740)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Interaction partners:
- Ribonuclease H2 subunit A
- Helicase SEN1
- THO complex subunit HPR1
- DNA topoisomerase 1
- Ribonuclease 3
- DNA repair and recombination protein RAD52
- Ribonuclease H2 subunit B
- DNA polymerase epsilon catalytic subunit A
- ATP-dependent DNA helicase RRM3
- FKBP12-associated protein 1
Sequence:
MARQGNFYAVRKGRETGIYNTWNECKNQVDGYGGAIYKKFNSYEQAKSFLGQPNTTSNYGSSTHAGGQVSKPHTTQKRVHRRNRPLHYSSLTSSSACSSLSSANTNTFYSVKSNVPNIESKIFNNWKDCQAYVKHKRGITFKKFEDQLAAENFISGMSAHDYKLMNISKESFESKYKLSSNTMYNKSMNVYCDGSSFGNGTSSSRAGYGAYFEGAPEENISEPLLSGAQTNNRAEIEAVSEALKKIWEKLTNEKEKVNYQIKTDSEYVTKLLNDRYMTYDNKKLEGLPNSDLIVPLVQRFVKVKKYYELNKECFKNNGKFQIEWVKGHDGDPGNEMADFLAKKGASRR
Protein: F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) (Q8VBV4)
Organism: Mus musculus (Mouse)
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter brings them to the SCF complex for ubiquitination. Mediates ubiquitination and subsequent degradation of CCNE1 and MYC. Identified substrates include cyclin-E (CCNE1 or CCNE2), DISC1, JUN, MYC, NOTCH1 released notch intracellular domain (NICD), NOTCH2, MCL1, RICTOR and probably PSEN1 (By similarity). Acts as a negative regulator of JNK signaling by binding to phosphorylated JUN and promoting its ubiquitination and subsequent degradation (By similarity). SCF(FBXW7) complex mediates the ubiquitination and subsequent degradation of NFE2L1. Involved in bone homeostasis and negative regulation of osteoclast differentiation. Regulates the amplitude of the cyclic expression of hepatic core clock genes and genes involved in lipid and glucose metabolism via ubiquitination and proteasomal degradation of their transcriptional repressor NR1D1; CDK1-dependent phosphorylation of NR1D1 is necessary for SCF(FBXW7)-mediated ubiquitination. Also able to promote 'Lys-63'-linked ubiquitination in response to DNA damage (By similarity). The SCF(FBXW7) complex facilitates double-strand break repair following phosphorylation by ATM: phosphorylation promotes localization to sites of double-strand breaks and 'Lys-63'-linked ubiquitination of phosphorylated XRCC4, enhancing DNA non-homologous end joining (By similarity).
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:11461910}. Chromosome {ECO:0000250|UniProtKB:Q969H0}. Note=Localizes to site of double-strand breaks following phosphorylation by ATM. {ECO:0000250|UniProtKB:Q969H0}.
Interaction partners:
- Cullin-1
- S-phase kinase-associated protein 1
- G1/S-specific cyclin-E1
- E3 ubiquitin-protein ligase RBX1
- S-phase kinase-associated protein 2
- Friend leukemia integration 1 transcription factor
- Myc proto-oncogene protein
- F-box/WD repeat-containing protein 1A
- Neurogenic locus notch homolog protein 1
- Transcription factor Jun
Sequence:
MNQELLSVGSKRRRTGGSLRGNASSSQVDEGQMNRVVEEDPQQQARHQEEEHTARNGELVGANPRPGDQNDTQQGQVEENNNRFISVDEDSSGNQEEQEEDEEHAGEQEEEEEEEEEEEEMDQESDDFDPSDDSSREDEHTHNSNVTNCSSVSDLPAHQLSSPFYTKTTKMKRKLDHGSEVRSFSLGKKPCKVSDYTSTTGLVPCSATPTTFGDLRAANGQGQQRRRITSVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKIIKPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
Protein: Maternal protein pumilio (P25822)
Organism: Drosophila melanogaster (Fruit fly)
Function: Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE). Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of deadenylase complexes leading to translational inhibition and mRNA degradation (By similarity). Also mediates deadenylation-independent repression by promoting accessibility of miRNAs. Mediates post-transcriptional silencing of E2f mRNA by binding to its 3'-UTR and promoting miRNA regulation. Required for abdominal development and to support proliferation and self-renewal of germ cells. Pum is the only gene required for nos activity that is not also required for posterior localization of germline determinants. Pum is required during embryogenesis when nos activity apparently moves anteriorly from the posterior pole.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:1576962}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000269|PubMed:17178403}. Note=It is concentrated in the cortical region of the embryo beneath the nuclei. {ECO:0000269|PubMed:1576962}.
Interaction partners:
- Protein nanos
- poly
- ATP-dependent RNA helicase me31b
- Protein brain tumor
- Cytochrome c oxidase copper chaperone
- Eukaryotic translation initiation factor 4E1
- Maternal effect protein staufen
- Protein sex-lethal
- Trailer hitch, isoform H
- 5'-3' exoribonuclease 1
Sequence:
MKFLGGNDDRNGRGGVGVGTDAIVGSRGGVSQDAADAAGAAAAAAVGYVFQQRPSPGGVGVGVGGVGGGVPGVGAVGSTLHEAAAAEYAAHFAQKQQQTRWACGDDGHGIDNPDKWKYNPPMNPANAAPGGPPGNGSNGGPGAIGTIGMGSGLGGGGGGGAGGGNNGGSGTNGGLHHQSMAAAAANMAAMQQAAALAKHNHMISQAAAAVAAQQQHQHPHQQHPQQQQQQQQAQNQGHPHHLMGGGNGLGNGNGLGIQHPGQQQQQQQQQQQQQHPGQYNANLLNHAAALGHMSSYAQSGGSMYDHHGGAMHPGMNGGMPKQQPLGPPGAGGPQDYVYMGGQTTVPMGAAMMPPQNQYMNSSAVAAANRNAAITTSTAKKLWEKSDGKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVPPPSRAYAHGGASDTSNSGNAGILSPRDSTCAKVVEYVFSGSPTNKDSSLSGLEPHLRNLKFDDNDKSRDDKEKANSPFDTNGLKKDDQVTNSNGVVNGIDDDKGFNRTPGSRQPSPAEESQPRPPNLLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPPMMNGVGGGMPMAAQSPMLNHQAAGPNHMESPGNLLQQQNFDVQQLFRSQNPGLAAVATNAAAAAAAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMAAASQQFLAAQQQAQNAAYAAQQATSYVINPGQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPSQQGAENQPYQVIPAFLDHTGSLLMGGPRTGTPMRLVSPAPVLVPPGATRAGPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVAAAANAVNSTVAQAAAAAAAAAAARGKWPGAMSGAASGAYGALGAGNASASPLGAPITPPPSAQSCLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIFSNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQQEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQHVLEHGKQEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTFNDNALHVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMKITNPITVGTGAGGVPAASSAAAVSSGATSASVTACTSGSSTTTTSTTNSLASPTICSVQENGSAMVVEPSSPDASESSSSVVSGAVNSSLGPIGPPTNGNVVL
Protein: Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 1) (Non-neural enolase) (NNE) (P04764)
Organism: Rattus norvegicus (Rat)
Function: Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
Subcellular location: Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
Interaction partners:
- Pyruvate kinase PKM
- Phosphoglycerate mutase 1
- Glucose-6-phosphate isomerase
- Phosphoglycerate mutase 2
- Pyruvate kinase PKLR
- Fructose-bisphosphate aldolase A
- Plasminogen
- Phosphoenolpyruvate carboxykinase, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase
- Fructose-bisphosphate aldolase C
Sequence:
MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSPDDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK
Protein: DBF4-type zinc finger-containing protein 2 homolog (Q5SS00)
Organism: Mus musculus (Mouse)
Interaction partners:
- Chemerin-like receptor 2
Sequence:
MEAQSYQEVMKNNGQHLFSSQHRSLTRQSRRRTATNNTLMERFLQDVLRHHPYNYQDNRSAPNEPEAAAAAAAAADPGSPEVVVVLDDSDEKEDDTADSGAERNSEDSGSVEEIDYRPGTSQEHAEVAVRPSVIQKLERGQQQSLELAHKVESGVKKVNSVGVVQATTSGKKLVRPPVICNAPASSLPSGSFERPVAANSVPRLVLAVASDSFPACDTENLETYFDSPDQGPSNPSSQPKTKDPKKKLSINLDKLLAQRNLRAKGASFSPVVRVRELTGSELCSVRAESSELEAGTAGNPRETDTLPEQAREGAIPKRREASRSNTVRPQEETRLVLNKPTLLKQKRSVSSEERFSCGSRQAVPGPSQAAVRDLSLLEEEVEEEKQEEEEEEEQEEEEEHEEEEEGVDQEDASYESRGSDMSFDCGSSCQSLSALSELTAREINVSEETHAYSQPRNETPTVSGATSDNGSSSRQVITQNIQLISLVDESYESSGSEVNFDGDDSLPSTSHRPPQPVEVVVPLRLVDKSYGSGSSEPCEDSGSSADETPAASRQQNPVRNTHANLVDENYGSSSFSSDSDAALDHPQVPVQEGSPRGRAVGQGNEEQPSSAEAHPERDGSLETVAHELQRESQEINLPNQKNTSLGDMNCESHGPEVGFHADAQLEADQSPVNPEEVDLDLENQSVHSGISNLSFDSNASYQSANDQPQGAWGEVNLDELNVDMEVKSNGCSSSELTFDSDSPLLSVTERSLLDFEGLNEDDFNLEDENCVSSSSDITFDSDIPDDSVADQPQVAVYEEEPVGLENKSNESCVSGITFDSDIPLHSGNDHPEVAVKEVIIKEDENVHLEGKNDNPSGSEICLDSNVPLHSVTNSDVAVKKINPPKEDQVQIEQIEQKENEPTDSELNLDCNSVNSKPGCSEDPIILRVSETRLDSHVPFQSVIRKCEVVVKNVCLQKEKHAELTSKSTESHSEVSSASTASHPVTEPYVGKKAKRKTKHLEEVNSDDEYGGSQPTFKFDVFPRTMTEKPQPAALKEGHADPKDKITELRGMAVNVNTADCLDSVLSQPQLASNENCVELKDTDGKPSDSKASADSTGHFHSLPKQEFDVVSKMNEWKKEAKVLEQKISDLIYSKIIHDSNVSFRSAMDQLELALKQISLGNNDQVSLEDNSQDTCSETNLDSGFSVQAVVEPPEPEVTVLEPEHVEQEGRNNVPCDSEVSVDANGSVQLEAGQHSESGENRSQKDTDDTEGKRDDAQGFGITCDSNVPQPLAGHIEVVQDIDHWKDHVDLEDKLGESKNSKVNFHSDEPLQAVTNATQEPVEEINLPRGRASPNGNGCEPYGSTIVPVTNVIFCSVIQKPQRLQKKCTSLKENSSNPCPEVNVDSCDGPEVSVDSNDPCQSVAGHLQKPDKEMNLKEDHIYLEDKSYKLVDFEPTYDSDDPVQFVTVPSVEAVSIKEVNLQKENPDDLENENFQPCCSEVACNSAVHLQSEADPPQVACKEADLDKKALDIEDKGSVTCVPEVVYDSDVSFQIVVNQVQTSDGETDSPQVVFVDVVSSDSDCDREVISDSNIPLQLEPPQMTVKETSDINTDSLGSAANEKYYCKFCGCDYEASQSVTNQSKESFKIINRKNDYIILGDSTCPSCGHELNFNVDPSDQPTTCQLQQPDRNFIDPEDKNFGSKCPKRKLNWEDTAHPVTHQLQKTGEATSLRKDQKNRFKRDRGWESSSFAGDHAAYAVSVIRQTALNSCGSELNFQDDTFYHSDIDPPQPKKKGQGKKVTFDLRVTKYEYPPNPMYGEGEEVAEDDLKEVVVHEASPQGQAPPSIVGKTCPQGREDDVKTNTQACQGYFYSYYDGGSETKKILLGEEEKTIRSDLNQNTTSIQHVKGKVGDTGDFSVDLGKQSCSLAEGLHQQHGQVTSQNQVEVRCGIQASSGKKRKITEQEEDSPKRKCFHHDSQKKKKAQAGITELPEPQTKVLEPVQPDSLVYIFSSLSMKEDQSLNPPKTKPGSDSDLPHIYSCREHTSSGPRRKRTVINPPQNLMVPEVGIDLNRHDPKPNAGDDSAKRQNLVSTSFMAMPKKSVLKFQRTNQSSFLKKSEDVGATQVPKDNFQQTLVNRDGAKKFPKSVKKEDLESQNQRKFWKKKMVAANKLCLIKNAYKTMVLRKKSKLASEKLAIWIQLKATDIIRKYVSRCHGLMPRRHLSKTVLIRMQLRKKKIVARKIKEAKRAAEALALKLSRPSCPPRAPCPPRALCPPRAPCPPRALCPPRAPCPPRALCTPRAPCPPRALCTPRAPCPPRALCTPRAPCPPRALRAPCPPRALCSPRAPCPPRALCPPRAPCPPRAPRAPCPPRAPCPPRAPCLPRAPCPPRAPCPPRAPCLPRAPCLPQAPCPPRALCLPRVSCPPLPLCAPCPPCAPVLPAGAEEQLSTTAGPAELPAHLSNAGGIKRYRKTYFRRRKRLLPVREYDLRSLSSTTNTDRMVTRLASKSKSNEAK
Protein: Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (Zgc:172284 protein) (B1H1J7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MARENGEAGGDCSWKKQVDNIKEIFEFKEVLGTGAFSEVVLAEERSTGKMYAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESSDHLYLIMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVNYLHTMGIVHRDLKPENLLYFNPQDGSKIMISDFGLSKMEGTGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKADYEFDAPYWDDISDSAKDFISCLMEKDPSKRNTCEQALRHPWIAGDTALCKNIHESVSRQMRKNFAKSKWRQAFNATAVVRHMRRLQLGSSMGSSMDQSNTANQNRILNANPPLNTTTNSTAPLTQNQKPAPNPNAILINDMATGNTPTPRKDCTAPPHTSCSLASAASSSSGAEPCRPLPPSVASVSTVVTGTK
Protein: Cell division control protein KAR1 (P11927)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: KAR1 is required for function of both intranuclear and extranuclear microtubules. KAR1 helps localize CDC31 to the spindle pole body (SPB), CDC31 then initiates SPB duplication via interaction with a downstream effector.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Interaction partners:
- Cell division control protein 31
- Protein SFI1
- Gamma tubulin complex adapter SPC72
- Kinesin-like protein KAR3
- Spindle pole body assembly component MPS3
- Spindle pole body component SPC97
- Spindle pole body component SPC42
- Spindle pole body-associated protein CIK1
- Spindle pole component BBP1
- Spindle pole body component SPC98
Sequence:
MNVTSPKDGNHSFSKKNRFNTNKPRFHKLNEQAQSINLPEDRDSIVSSNTTSIMTDDAFDYNEGIASRTKNINSDSDRSNDTIKQNNYNKRETGYNPFYNGSGINQRYTQFRKREFEPTLAENKAEEYISDEDNVKIDEDNIENELQFTPKIKEASILRSSLLGQRNVLNTRNPKSKESHIKVKPIINNKSSSQRKSSAALRKQLGKPLPLPYLNSPNSDSTPTLQRKEEVFTDEVLQKKRELIESKWHRLLFHDKKMVEKKLESLREYERKRMPPRGTDVSSSEQDNSFKISTPTKSYVSLEQKPLPNLSAMNNFNDVTDNKEKEETNNNILKFQAQRDPLQILQSEIEMHTKKLDTIIELLKDDTDSKEKRKVVTNDNAAPEQMVNKGWRKNVMMIYKKSGNIMKKYREYFLWTICILILLYCNIYVYYRF
Protein: Pantothenate kinase 1a (EC 2.7.1.33) (F1QB40)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Bifunctional coenzyme A synthase
- Phosphopantothenoylcysteine synthetase.
- Phosphopantothenoylcysteine decarboxylase.
- pantothenate kinase
- Ectonucleotide pyrophosphatase/phosphodiesterase 1
- Pantothenate kinase 1b.
Sequence:
MKLKCSWKPAFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRRYLTSNTAYGKTGIRDVHLELRNLTICGRTGNLHFIRFPTAAMHRFIQMGRDKHFSSLHTTLCATGGGAYKFENDFRTMADLELLKLDELDCLIQGLLYIDSVGFNGHPECYYFENPSDTQNCIKRPCRLDNLFPMLLVNIGSGVSILAVNSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSTNVDKLVKDIYGGDYQRFGLQGSAVASSFGHMMSKEKRDSISKEDLARATLVTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHEGYFGAVGAFLELLKSSEDA
Protein: Aminopeptidase N (AP-N) (rbAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13) (P15541)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P15144}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P15144}. Note=Also found as a soluble form. {ECO:0000250|UniProtKB:P15144}.
Interaction partners:
- Gamma-glutamyltransferase 6
- Glutathione hydrolase
- Gamma-glutamyltransferase 5
- Glutamate--cysteine ligase
- Cytosol aminopeptidase
- Glutamate--cysteine ligase regulatory subunit
- Glutathione synthetase
- Gamma-glutamylcyclotransferase
- Gamma-glutamylcyclotransferase
- N-acetyltransferase 8
Sequence:
MAKGFYISKSLGILGILLGVAALCTIVALSVVYRQEKNKNTSQSPSMAPLNPTATSSPATTLDQNLPWNRYRLPKTLIPDSYNVVLRPYLSPNSQGLYIFTGSSTVRFTCQEATNVIIIHSKKLNYTITQGHRVVLRGVRGSQPPAIASTELVELTEYLVVHLQGQLVAGSQYEMDTQFQGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKATFNITPIHPRDYTALSNMLPRSSTALPEDPNWTVTEFHTTPKMSTYLLAYIVSEFTNIEAQSPNNVQIRIWARPSAISEGHGQYALNVTGPILNFFANHYNTPYPLEKSDQIGLPDFNAGAMENWGLVTYRESALLFDPLVSSISNKERVVTVVAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLIVLNELHSVMAVDALASSHPLSSPADEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKEGLASYLHTFAYQNTIYLDLWEHLQQAVNSQSAIQLPASVRDIMDRWILQMGFPVVTVNTTNGIISQHHFLLDPTSNVTRPSDFNYLWIVPVSSMRNGVLEQEFWLEGVEQTQNSLFRVEGDNNWILANLNVTGYYQVNYDEGNWKKLQTQLQTNPSVIPVINRAQIIHDAFNLASAQKVPVTLALDNTLFLIRETEYMPWQAALSSLNYFKLMFDRSEVYGPMKNYLSKQVRPLFEHFKNITNDWTRRPDTLMDQYNEINAISTACSNGIQECETLVSDLFKQWMDDPSNNPIHPNLRTTVYCNAIALGGEREWDFAWEQFRNATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRRQDATSTINSIASNVIGQTLVWDFVQSNWKKLFEDFGGGSFSFANLIRAVTRRFSTEYELQQLEQFRLNNLDTGFGSGTRALEQALEQTRANIKWVQENKEAVLAWFTANSA
Protein: Dof protein (O96758)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
TMALGSPRGSFNSLAGYPQHAIELQTMNMYRQRSANSHSEFRERLNSCNETHSSQCPGGGGASVAGDHNEVFNPLTSPTSSKSHRHHTLPSGGTRRHSLGNWAQHQHQQQHQQNSGAMGLGSPDEVPSMMAPRPPLLSPNKFRGSSHRRRDNCGNVNNTSGSSASGFLGSPGYNMDDILIITAKHSERAYLRATFLKNHFDKITKQRGRKPFNFLHIKIDDGPFSEEIAHKYQNTALQIVILCPALLALPHSFLMTQLSAIIRVEKVLAILLDVSEEKVKEMHKSALPSYYKWRRCVVRDNDQVQISNILGIATDILGRALCQRPPCQDSSGGGGGGLSRSFSSCTEGFTVLPKKVKLGQNKVVALLAEPLEKNDTLKLLVEKSGELIELRNFKCRNPYTLQFNIPEACMEISTMIEIRIEKNNKSLGARPIKCESRLRELEQLLRIEDSPIEFMCHALGIGPVERDALDQHLLQCFQRNMPPNFHLLSGPSERQPHFFTRLESSPEEYPTLLHFAARWGLNRLCIQLMECPGGDTACGVRNCAGRTPAELAEQEGHHKLAQNIVSFAEFHELTTMYHYFKGVTPPGESCPKPSANVVIEAHPGKAGKTNKPPKELPTAEYMEMSSGSERENTPEVRTKTETLAISNLNYISVETEDENLQASVAEKKVESEKKLPEAGNQPGPEKTTNELRINEPPYYQSKEQNQQPKELKNQSKSLDEVDAAPLYQTDKFSQECSQLLENQLGNDYVLQPSNVPVAQDDGNYLFQPSNRPVEEPLRLNRCTNRQPGYGTLKRSASDASAASHTRSNADDELAEIMHDFKNNVLSIRDVEVLVERWKHRNDVQQSFREKQDQIDQLRREYERIQEQVKSHLKRETPFERIKKFFLRSKTPGGNDSLLDETKSSIATSCSFKSAGGVSSSAGAGRPISSLSLQSVSSSSSSSGRLSTGSNCSGASLGDSGTHSDHEDRRFQHCRMMDNYMVPPTPRPVFTPSSTPGDERHQIVFPSPMSSCQRLNTPTSPTGSEHYQMFPSNIPVYGSQPLVGSQSSNYLNTIMEAKEQAETQHYQNQNGVTLQPIKLNERSNIIYGKLTKSSSASGCSSFKPKQIPVPCPQVGSIEVQAEVYQNVGDVAPEKDSKAEEETPNYMNC
Protein: Protein YIF1A (54TMp) (YIP1-interacting factor homolog A) (O95070)
Organism: Homo sapiens (Human)
Function: Possible role in transport between endoplasmic reticulum and Golgi.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15308636}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:15308636, ECO:0000269|PubMed:15990086, ECO:0000269|PubMed:26077767}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:26077767}; Multi-pass membrane protein {ECO:0000255}. Note=Cycles between the endoplasmic reticulum and the endoplasmic reticulum-Golgi intermediate compartment. {ECO:0000269|PubMed:15308636}.
Interaction partners:
- Protein YIPF5
- Protein YIPF4
- Prenylated Rab acceptor protein 1
- Ras-related protein Rab-1A
- X-box-binding protein 1
- Protein YIPF7
- Vesicle-associated membrane protein-associated protein B/C
- Protein YIPF3
Sequence:
MAYHSGYGAHGSKHRARAAPDPPPLFDDTSGGYSSQPGGYPATGADVAFSVNHLLGDPMANVAMAYGSSIASHGKDMVHKELHRFVSVSKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDAPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGLYLATVRSDLSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGPDSMGGPVPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR