wanglab/gogpt-training-data huggingface dataset:
Protein: ATP synthase F(1) complex subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit) (P30049)
Organism: Homo sapiens (Human)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular location: Mitochondrion. Mitochondrion inner membrane.
Interaction partners:
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit d, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit F6, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- ATP synthase F
Sequence:
MLPAALLRRPGLGRLVRHARAYAEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE
Protein: E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (RING finger protein 109) (Tripartite motif-containing protein 56) (Q9BRZ2)
Organism: Homo sapiens (Human)
Function: E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity by mediating ubiquitination of CGAS and STING1. In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets STING1 to 'Lys-63'-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta (By similarity). Also mediate monoubiquitination of CGAS, thereby promoting CGAS oligomerization and subsequent activation. Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling. Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES. Promotes establishment of an antiviral state by TLR3 ligand and TLR3-mediated chemokine induction following infection by hepatitis C virus.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21289118}.
Interaction partners:
- Stimulator of interferon genes protein
- E3 ubiquitin-protein ligase TRIM32
- FAS-associated factor 2
- E3 ubiquitin-protein ligase TRIM38
- Cyclic GMP-AMP synthase
Sequence:
MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSGDRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
Protein: Syntaxin-7 (O70257)
Organism: Rattus norvegicus (Rat)
Function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity).
Subcellular location: Early endosome membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Interaction partners:
- Vesicle-associated membrane protein 8
- Vesicle transport through interaction with t-SNAREs homolog 1B
- Syntaxin-8
- Vesicle-associated membrane protein 7
- Synaptobrevin homolog YKT6
- Synaptosomal-associated protein 29
- Vesicle transport through interaction with t-SNAREs homolog 1A
- Syntaxin-6
- Alpha-soluble NSF attachment protein
- Vesicle-associated membrane protein 3
Sequence:
MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKETDKYIKEFGFLPTTPSEQRQRKIQKDRLVAEFTTALTNFQKVQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNFVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQQANQQLSRAANYQRKSRKTLCIIILILVVGIVIIFFIVWGLKG
Protein: Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) (Q08210)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- NADH-cytochrome b5 reductase, putative
- orotate phosphoribosyltransferase
- Dihydroorotase, putative
- Orotidine 5'-phosphate decarboxylase
- aspartate carbamoyltransferase
- Protein transport protein GOT1, putative
- carbamoyl-phosphate synthase
- GMP synthase
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- Cytochrome b
Sequence:
MISKLKPQFMFLPKKHILSYCRKDVLNLFEQKFYYTSKRKESNNMKNESLLRLINYNRYYNKIDSNNYYNGGKILSNDRQYIYSPLCEYKKKINDISSYVSVPFKINIRNLGTSNFVNNKKDVLDNDYIYENIKKEKSKHKKIIFLLFVSLFGLYGFFESYNPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKHIVGVSIGKNKDTVNIVDDLKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDESTYNEDNKIVEKKNNFNKNNSHMMKDAKDNFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQINDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVFNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHSKS
Protein: Tetraspanin (B0BNE7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
Interaction partners:
Sequence:
MASRRMETKPVITCLKTLLIIYSFVFWITGAILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGKDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLEHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV
Protein: Nuclear receptor corepressor 2 (E7FF48)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Histone deacetylase 3
- Histone deacetylase 1
- Recombination signal-binding protein for immunoglobulin kappa J region a.
- Recombination signal-binding protein for immunoglobulin kappa J region b
- Recombination signal-binding protein for immunoglobulin kappa J region-like.
- Estrogen receptor
- Nuclear receptor subfamily 1 group D member 1
- BCL6A transcription repressor a
- Progesterone receptor.
- Transcription initiation factor TFIID subunit 9
Sequence:
MSSHPQPVPQGRRAVDARHLSSAANLPLQLRAHTDVGGLVDYHPHARDYGLTHGSLVQPHRRRPSLLSEFQPGNEREPHIRYEHIYLQDASSQSEVEYSEMKRPRLEIGAESLIRHSSHRQALTVGGAEEMAKEHSSSSSIGKIEPISPVSPVPMEADLDLVPSRLSKEELIQNMDRVDREITMVEQQISKLRKKQQQLEEEAAKPQEPERTISPPPSEAKHRSLVQIIYDENRKKAEEAHRILEGLGPRVELPLYNQPSDTKQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQNRVAQRGGGLASAARSEHEVSEIIDGISEQENSEKQMRQLAVIPPMLFDAEQQRIKFINMNGLMDDPMKVYKDRQVMNMWSEQEKDTFREKFIQHPKNFALIASFLERKTVAECVLFYYLTKKNENYKNIVRRSYRRRGRSQNNQQAQQQVNRNNQEEKEDKEKEKEGEREEDKAEGDDKEDGIKDDTSGEDGEEKEPPVTVKGRRTANSRGHRKGRVTRSMTNEQEENTSPLGSELANLEMNESSRWTEEEMETAKKGLLQYGRNWSAIAKMVGSKTVSQCKNFYFNYKKRQKLDEILQQHKIKSEKERKARRKGKAPQNEEASAPSAAEEEEMEGSGVSGNEEEAQEDGEGGANNSSDTESLPSPRSSDDSKVKEEGSARPKTAPNATSSSSSTDKDMAAAETGMDEKPKVEKGDGEQAGVKQEVKTEPGEGASESAGEDKKPPALEVEEGKKEVKKKEHGGKSGAHDSDSSATCSADEVEETESSEKSRPSLLSFSHDGVISSQAQKPLDLKQLKQRAAAIPPILPEVSGRDNRPGLPGKQAMPDALALYQQQITMAHESSQEAKQQQQQQPTKSQHYPAAGDSGSPRVRTRSPGISDREREDGKKNPGADDIRALGLGRPVMSSYLSPRDMAKFSQEQLLHYNPSLASTLQPQDRMAAVRPLHIPEPPPLISSAKPGGSITQGTPVQLHNPSHGSEHGKVPAPGSLALSWVDQRKMGGFPVVKQEQLSPRGASSSSSQAENLSTQDSSTSRGPMPAVQGGSITKGIPGTRVHQDSPISYRGGSITQGTPADVLYKGTITRLINEDSPSRERSREDTPSKGHVVYEGISGHILSFERRPNSKEEGCGDVGAGMKRSYDMMEVGISSRVPPIRDPLSEGLIIRAMPPDRDSPHPQLIRGSISQGIPRDDCQRREVKQMKREGSPSPRGPGHSTDALKSRSHESMVPTVKEGGRSIHLIPPEGVVIGKPKEGSITQGTPLKQEPPGSSKRHDVRSIIASSPRPYSGLPSHLDPRGSDRARYEEAGGKSRPSAVVSAPSSLSRVSPLALSGEQSSRPHHSPVGYEDHKRSSYPPPSHRASPLSGRENSQRAHEGSSKPQQQERKATPTPREMGSTKSPLAVGEHTANLAFERILGLGPDMYRSQMSHLTFDAAALPRGIPIDSAYYLPRHLAPGPGYPHPYPPYLIRGCFPETAALENRQTLFNDYITSQQMHQWPAAAAMAAQRPDLLRGLTPREQSLNLAYSPTPRGTSASPMDRITYIPGTSPGFPSGAYNTSPISPVGASHMSKIQGGSSSAEREREREREREREQRERERERERERDRERDRDREREKDRDRDRERDKSLSHGNVEHAPIWRPGAPEQMSGSSSRPPSHPYSHQSPLSPRPQDSLQQRPSVLHNTSSKSLSNSEHNNPSVLRPPGSARYQGFSGHLQRSGLPGEGYPSGTDPSAKDLSRDGGKSHGRGGLPKHQDLSSSSKSDSKLASPGAGGTYPSPYNQAPVAHLPTSRGHPLLAPESGGGGSSIQSRGGDSGSSASSREKTQNKVMSIQEHELRALAVSAAQQKAFEQLYGSEDRLSPGQQSSSGVKGSQRVVTLAQHISEVITKDYTRQSQQNQIGGQPSLPPGYGYHSSPVLDLTRPPSTPQAQTPTEPNSRYTPEGTSAERGRDRSPPQNKTSPVSLAADGIEPVSPPGAISEPETPGANYPNEQAEQGMGSRSPASSSQPPAFFSKLTESNSAIVKSKKEMIKKISAEAEFNQSQPGTEIFNMPVSTNAGPVSVRSHPPPEASGNTIGLEAIIRKALMGKYDEQMDERSPSNSVNSMAAGGAAAVVPPASADGRSEDPYSLPGKSKGGRSNGRKTKSPGPGLSGGERPSSVSSVHSEGDCNRHTPLTNRVWEDRPSSTGPTPFPCNPLTMGMRLPSGIMPGPSPSPTHPGASAPTQGQTQPRTWEEEPKPLLCSQYETLSDSE
Protein: Triosephosphate isomerase (EC 5.3.1.1) (G4V6B9)
Organism: Schistosoma mansoni (Blood fluke)
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase
- Phosphoglycerate kinase
- Glyceraldehyde-3-phosphate dehydrogenase
- Phosphoglycerate kinase
- Transaldolase
- Glucose-6-phosphate isomerase
- Putative cleavage stimulation factor
- Fructose-bisphosphate aldolase
- Pyruvate kinase
- Enolase
Sequence:
MSGSRKFFVGGNWKMNGSRDDNDKLLKLLSEAHFDDNTEVLIAPPSVFLHEIRKSLKKEIHVAAQNCYKVSKGAFTGEISPAMIKDIGCDWVILGHSERRNIFGESDELIAEKVQHALAEGLSVIACIGETLSERESNKTEEVCVRQLKAIANKIKSADEWKRVVVAYEPVWAIGTGKVATPQQAQEVHNFLRKWFKTNAPNGVDEKIRIIYGGSVTAANCKELAQQHDVDGFLVGGASLKPEFTEICKARQR
Protein: Pdp3-interacting factor 2 (O60127)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Mst2 complex subunit nto1
- Chromatin modification-related protein eaf6
- Histone acetyltransferase mst2
- Pdp3-interacting factor 1
- PWWP domain-containing protein 3
- Uncharacterized AIM2 family protein C977.15
- PWWP domain-containing protein2
- PWWP domain-containing protein 1
Sequence:
MDEIQESSCNEKLSDEDLAAEFVEFTDNIPIEIYRSLRYIRKYENFFAKENENLNTAARLVCDCPISEVPSAKQKLADSLFTSHEYLRQTSAEANKLYENVLASYKHLCEKIKYLEADNPLYVPAP
Protein: UDP glucuronosyltransferase family 1 member A6 (C9JMY5)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPDPV
Protein: Protein FAM83G (Protein associated with SMAD1) (A6ND36)
Organism: Homo sapiens (Human)
Function: May regulate the bone morphogenetic proteins (BMP) pathway.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:24554596}. Nucleus {ECO:0000269|PubMed:24554596}. Note=Detected predominantly in the cytosol. Upon BMP stimulation, a small portion localizes the nucleus. {ECO:0000269|PubMed:24554596}.
Interaction partners:
- Casein kinase I isoform alpha
Sequence:
MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP
Protein: Transcription repressor OFP12 (Ovate family protein 12) (AtOFP12) (F4I8R6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription repressor OFP17
- Transcription repressor OFP2
- Transcription repressor OFP6
- Transcription repressor OFP3
- Transcription repressor OFP5
- Transcription repressor OFP1
- Transcription repressor OFP8
- Transcription repressor OFP4
- Probable transcription repressor OFP9
- Transcription repressor OFP10
Sequence:
MPRVMWKNFHLCFPSNLTKPSSSPSGATSDDPNRPSILLINNFNLLYDDSSAAHRRLSKPLIHDVEPSSTFTASTSTAANSSSSSASYDDSDNYGFAPDDDSPPPDLTAVLASRRFFFSSPGCSNSITDSPDLRCRDNYDTATRLLTGGTAVKHYVQSPDPYNDFRRSMQEMIDAVTNAGDLRRYEFLHELLLSYLSLNAADTHKFIIRAFADILVSLLSDGHRIS
Protein: NOP5/NOP56 related protein (Q8U4M1)
Organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Interaction partners:
- Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
- Large ribosomal subunit protein eL8
- Small ribosomal subunit protein eS6
- Probable tRNA pseudouridine synthase B
- tRNA
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS4
- K Homology domain-containing protein
- Ribosomal RNA small subunit methyltransferase Nep1
- GTP-binding protein, gtp1/obg family
Sequence:
MKAFISENVRGIYAFDENGNLIEKRYFTDKPEKVLDQLLKGEITKDLEELLNSLKEKGYDEFVFEHPELSRRAKELGFSATTEFPNIAGERLRSNPEEFLGENWFEEYYKVGVALTRMRIQEQSGARDKMVIQAIEALDDVDKVINLLVARLREWYSLHFPELDELLPKHPQYVAFVKTVGHRDNINEEVLRELGLSEEKIKKILEAKEKTMGAWMDQTDIEVVRQLAEEIDRLYQLRKKLEDYIDRAMDDVAPNLKALVGAKLAARLISLAGGLRELAMMPSSTIQVLGAEKALFRHLRTGAKPPKHGVIYQYPAINRSPWWQRGKIARALAGKLAIAARVDYFSGEYIAEELKKELEARIREIKEKYPKPPKRKREERKGKKPWKKDKKKKKKKEKPRRR
Protein: Cytochrome P450 78A5 (EC 1.14.-.-) (Protein KLUH) (Q9LMX7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in regulating directional growth at the meristem/organ boundary. Is required for the promotion of leaf and floral organ growth and for the prolongation of the plastochron. Promotes organ growth in a non-cell-autonomous manner and may generate a mobile growth signal distinct from the classical phytohormones that prevents premature arrest of proliferation, until the correct primordium size has been reached. Functions probably in association with CYP78A7 in regulating relative growth of the shoot apical meristem and plant organs. Is required locally in developing ovules to stimulates cell proliferation and promote seed growth.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- GRF1-interacting factor 1
- E3 ubiquitin-protein ligase BIG BROTHER
- Protein AUXIN-REGULATED GENE INVOLVED IN ORGAN SIZE
- E3 ubiquitin-protein ligase DA2
- F-box/LRR-repeat protein 15
- Probable glutamate carboxypeptidase AMP1
- Phosphate transporter PHO1 homolog 4
- Ubiquitin carboxyl-terminal hydrolase 15
- B3 domain-containing protein At5g06250
- GRF1-interacting factor 2
Sequence:
MSPEAYVLFFNSFNLVTFEAFASVSLIIATVAFLLSPGGLAWAWTGSSKSRVSIPGPSGSLSVFSGSNPHRVLAALAKRFKASPLMAFSVGFSRFVISSEPETAKEILSSSAFADRPVKESAYELLFHRAMGFAPYGEYWRNLRRISSTHLFSPRRIASFEGVRVGIGMKMVKKIKSLVTSDACGEVEVKKIVHFGSLNNVMTTVFGESYDFDEVNGKGCFLERLVSEGYELLGIFNWSDHFWFLRWFDFQGVRKRCRALVSEVNTFVGGIIEKHKMKKGNNLNGEENDFVDVLLGLQKDEKLSDSDMIAVLWEMIFRGTDTVAILVEWVLARMVLHQDIQDKLYREIASATSNNIRSLSDSDIPKLPYLQAIVKETLRLHPPGPLLSWARLAIHDVHVGPNLVPAGTIAMVNMWSITHNAKIWTDPEAFMPERFISEDVSIMGSDLRLAPFGSGRRVCPGKAMGLATVHLWIGQLIQNFEWVKGSCDVELAEVLKLSMEMKNPLKCKAVPRNVGFA
Protein: Vascular non-inflammatory molecule 3 (Vanin-3) (Q9QZ25)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. Note=According to PubMed:11491533, secreted. {ECO:0000269|PubMed:11491533}.
Interaction partners:
- Pantothenate kinase 3
- Pantothenate kinase 2
- Pantetheinase
- Pantothenate kinase 1
Sequence:
MASLHFPQWAVSFVFFAQAVGSMDTFIAAVYEHAVILPNKTESPVSTEEALLLINKNIDILESAIKLAARQGAHIIVTPEDGIYGWIFTRETIYPYLEDIPDPEVNWIPCRDPRRFGYTPVQERLSCLAKENSIYIMANIGDKKPCNATDPHCPPDGRYQYNTNVVFDSKGRLTARYHKYNLFEPEIQFDFPKDSELVTFDTPFGKFGIFTCFDIFSYDPAVVVVKDTQVDSVLLPTAWYNTLPLLSAVPFHSVWARAMGVNVLAANTHNTSMHMTGSGIYSPEAVRVYHYDMETESGQLLLSELRSRPRQHATPAEVNWSAYARTVKPFSSGQADFPGKIYFDEFSFTKLTGSAGNYTVCQKDLCCHLTYKMSESRMDEVYVLGAFDGLHTVEGQYYLQICTLLKCQTTNSRTCGEPVGSAFTKFEEFSLSGTFRTKYVFPQIVLSGSQLALERYYEVSRDGRLRSRGGAPLPILVMALYGRVFERDPPRLGQGPGKLQ
Protein: DNA repair/transcription protein MET18/MMS19 (Methyl methanesulfonate-sensitivity protein 19) (P40469)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Key component of the cytosolic iron-sulfur protein assembly (CIA) machinery that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. Acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as RAD3/XPD and DNA2, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Cytosolic iron-sulfur protein assembly protein 1
- MIP18 family protein YHR122W
- General transcription and DNA repair factor IIH helicase subunit XPD/RAD3
- Cytosolic Fe-S cluster assembly factor NBP35
- Cytosolic Fe-S cluster assembly factor NAR1
- NADPH-dependent diflavin oxidoreductase 1
- Fe-S cluster assembly protein DRE2
- DNA replication ATP-dependent helicase/nuclease DNA2
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2
- DNA polymerase delta catalytic subunit
Sequence:
MTPDELNSAVVTFMANLNIDDSKANETASTVTDSIVHRSIKLLEVVVALKDYFLSENEVERKKALTCLTTILAKTPKDHLSKNECSVIFQFYQSKLDDQALAKEVLEGFAALAPMKYVSINEIAQLLRLLLDNYQQGQHLASTRLWPFKILRKIFDRFFVNGSSTEQVKRINDLFIETFLHVANGEKDPRNLLLSFALNKSITSSLQNVENFKEDLFDVLFCYFPITFKPPKHDPYKISNQDLKTALRSAITATPLFAEDAYSNLLDKLTASSPVVKNDTLLTLLECVRKFGGSSILENWTLLWNALKFEIMQNSEGNENTLLNPYNKDQQSDDVGQYTNYDACLKIINLMALQLYNFDKVSFEKFFTHVLDELKPNFKYEKDLKQTCQILSAIGSGNVEIFNKVISSTFPLFLINTSEVAKLKLLIMNFSFFVDSYIDLFGRTSKESLGTPVPNNKMAEYKDEIIMILSMALTRSSKAEVTIRTLSVIQFTKMIKMKGFLTPEEVSLIIQYFTEEILTDNNKNIYYACLEGLKTISEIYEDLVFEISLKKLLDLLPDCFEEKIRVNDEENIHIETILKIILDFTTSRHILVKESITFLATKLNRVAKISKSREYCFLLISTIYSLFNNNNQNENVLNEEDALALKNAIEPKLFEIITQESAIVSDNYNLTLLSNVLFFTNLKIPQAAHQEELDRYNELFISEGKIRILDTPNVLAISYAKILSALNKNCQFPQKFTVLFGTVQLLKKHAPRMTETEKLGYLELLLVLSNKFVSEKDVIGLFDWKDLSVINLEVMVWLTKGLIMQNSLESSEIAKKFIDLLSNEEIGSLVSKLFEVFVMDISSLKKFKGISWNNNVKILYKQKFFGDIFQTLVSNYKNTVDMTIKCNYLTALSLVLKHTPSQSVGPFINDLFPLLLQALDMPDPEVRVSALETLKDTTDKHHTLITEHVSTIVPLLLSLSLPHKYNSVSVRLIALQLLEMITTVVPLNYCLSYQDDVLSALIPVLSDKKRIIRKQCVDTRQVYYELGQIPFE
Protein: 5'-nucleotidase (Q5B0J1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- NAD
- Nicotinamide-nucleotide adenylyltransferase
- Purine nucleoside phosphorylase
- AMP deaminase
- Adenine deaminase
- Uridine nucleosidase Urh1, putative
- adenosine deaminase
- Adenosine kinase
- adenine phosphoribosyltransferase
- Adenylosuccinate synthetase
Sequence:
MKSSLSLAALAAAGTVLADDYLYSKRLAKRFVDDEGHYNVSFFHVNDVHAHLDQFASSGTSCDDPEKGCYGGYARIKTKVTELREQYPDNLWLNAGDEFQGTLFYTYYGGEKIAETLNELKFDAMTLGNHEWDGGDEALGQFLLNLTFPIVSCNVKSEVESLNETIKNYHIFEEHEIAVIGATTTTTPGISSVGNTTTFLDPVAEVQKAVWQIRNETEVNRIILLSHLGYEEDQDLAAKTEGISLIIGGHSHTLLGDMEDAKGDYPTIVEDLNGHEVFIVTAYRWGEYLGAIDLTFDDDGHALAYHGAPIHMDNSTSLDEELDTKIQGWAEAFADFAAEVLGETDAVLVQETCQEGDCLLGQVMADAMYEYRYNQTEGTDDEPALALINSGGVRAEINEGPITRGEVLTAFPFGNAIVELEFSGADLRKILEGAVSYVNQFNGDEITSWFQVSRGVRIEFNPDNEPGDRLVNVTIQGEAIDDERDYRVVTLDFLAGGGDSIFVATDDFITLDTQDEVLTQYIVARTPLSPELEERVVENDGQGENADESQNDEVDGPSDAAGMLAVPAWTALAGIAVAIMAM
Protein: Probable mitochondrial import receptor subunit tom40 (Translocase of outer membrane 40 kDa subunit) (O13656)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Channel-forming protein essential for import of protein precursors into mitochondria.
Subcellular location: Mitochondrion outer membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Mitochondrial import receptor subunit tom22
- SAM50-like protein SPAC17C9.06
- Mitochondrial import receptor subunit tom20
- Mitochondrial import receptor subunit tom7
- Probable mitochondrial import receptor subunit tom70
- Mitochondrial distribution and morphology protein 10
- Metaxin-like protein C409.19c
- Mitochondrial import inner membrane translocase subunit tim50
- Metaxin-1
- Mitochondrial import inner membrane translocase subunit tim23
Sequence:
MDYIQTLFTSVNQVGEKIDSYKSSLNLINPGTCENLSKEVSKDILLSNYAFTGVRADVTKGFCTSPWFTVSHAFALGSQVLPPYSFSTMFGGEPLFLRGSVDNDGAVQAMLNCTWNSNVLSKVQMQLSNGAVPNMCQIEHDHKGKDFSFSFKAMNPWYEEKLTGIYIISLLQSVTPKLSLGVEALWQKPSSSIGPEEATLSYMTRYNAADWIATAHLNGSQGDVTATFWRKLSPKVEAGVECQLSPVGLNHSAALMTGPKPEGLTSVGVKYEFAQSIYRGQVDSKGRVGVYLERRLAPAITLAFSSELDHPNRNAKVGLGLSLELPGSDEMIQQQQQQLAAQTA
Protein: Hexon protein (CP-H) (Protein II) (P04133)
Organism: Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Function: Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04051}. Host nucleus {ECO:0000255|HAMAP-Rule:MF_04051}. Note=Forms the capsid icosahedric shell. Present in 720 copies per virion, assembled in 240 trimers. {ECO:0000255|HAMAP-Rule:MF_04051}.
Interaction partners:
Sequence:
MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNPCEWDEAATALEINLEEEDDDNEDEVDEQAEQQKTHVFGQAPYSGINITKEGIQIGVEGQTPKYADKTFQPEPQIGESQWYETEINHAAGRVLKKTTPMKPCYGSYAKPTNENGGQGILVKQQNGKLESQVEMQFFSTTEATAGNGDNLTPKVVLYSEDVDIETPDTHISYMPTIKEGNSRELMGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGVINTETLTKVKPKTGQENGWEKDATEFSDKNEIRVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYSPSNVKISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGILHQHNNSGFVGYLAPTMREGQAYPANFPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHRPHRGVIETVYLRTPFSAGNATT