wanglab/gogpt-training-data huggingface dataset:
Protein: Xyloglucan O-acetyltransferase 4 (PtrXGOAT4) (EC 2.3.1.-) (A0A2K1X4I9)
Organism: Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
Function: Xyloglucan acetyltransferase that catalyzes the acetylation of fucosylated Gal residues on xyloglucan side chains. Predominantly catalyze 6-O-monoacetylation of Gal residues in the Fuc-Gal-Xyl trisaccharide side chains of xyloglucan oligomers.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MTMHEKMKLPSCSCSAFKCGKKDRWLNMERPIPFLLIGLTTILSVFILYTLNPLKFVIEHNIDQKLLLIKPHKEEDKCDLFNGNWVPDFEGSIYTNSSCATIPTSKNCFRNGRKDQDFLNWRWKPERCDLPRFDATAYLDIVRGKTLAFIGDSVARNHIESLLCLLSQKEVPVDAYLDSEDRNRIWHFPVHNFTLKMLWTKFLVHGEERVINGSSSGIFDLYLDKVDENWARDLHSLDYVVISDAHWFFRQVYLHRGSNVVACVYCNEANVTDRGVAFALRMAFRAAFSQINHCNKCKGIVTLLRTFSPSHFENGFWNTGGSCNRTSPYNDQKINFGAYEWEIRSMQVEEIERAEKRGKKGKSFGVLDVTMAMLMRPDGHPGAFWGNQWMKGYNDCVHWCLPGPIDVWNDLLLAVLRRLD
Protein: Protein transport protein Sec24B (SEC24-related protein B) (O95487)
Organism: Homo sapiens (Human)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269|PubMed:10075675}; Peripheral membrane protein {ECO:0000305|PubMed:10075675}; Cytoplasmic side {ECO:0000305|PubMed:10075675}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:10075675}; Peripheral membrane protein {ECO:0000269|PubMed:10075675}; Cytoplasmic side {ECO:0000269|PubMed:10075675}. Cytoplasm, cytosol {ECO:0000269|PubMed:10075675}.
Interaction partners:
- Protein transport protein Sec23A
- Protein transport protein Sec16A
- Protein SEC13 homolog
- Protein transport protein Sec23B
- Protein transport protein Sec31A
- Small COPII coat GTPase SAR1A
- Protein transport protein Sec31B
- Guanine nucleotide-exchange factor SEC12
- Small COPII coat GTPase SAR1B
- Protein transport protein Sec24D
Sequence:
MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLLHVQQQICK
Protein: Syncrip, isoform M (A0A0B4KGK5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNKFVSHNLGRDPYRTFSPEMYPLSSPLGPHGTEMAEGNGELLDDINQKADDRGDGERTEDYPKLLEYGLDKKVAGKLDEIYKTGKLAHAELDERALDALKEFPVDGALNVLGQFLESNLEHVSNKSAYLCGVMKTYRQKSRASQQGVAAPATVKGPDEDKIKKILERTGYTLDVTTGQRKYGGPPPHWEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRLMMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDELIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWADPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQYGKVERVKKIKDYAFIHFEDRDSAVEAMRGLNGKEIGASNIEVSLAKPPSDKKKKEEILRARERRMMQMMQARPGIVGNLSPTHPSIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFSDYRQGGSFGNNVSYYDDMYRWIDGDYNYYDYPNGGGGGSGGGGGSVSGGTVLPLSAGGSQNSPMASGQRSARGSASGPSASPSLMGVGRGHGITVPRGRVVGQRGSISRLGAQTVPQAAGAAAAAGQAAAAVAQRGATGQGAPAATGGFRGVLPTRPSARGTQHVKPLQNLPAGAAFKTFMEGN
Protein: NAC family protein (Transcription factor) (F1T115)
Organism: Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
Interaction partners:
Sequence:
MTENMSISVNGQSQVPPGFRFHPTEEELLDYYLRKKVSYEKIDLEVIRDVDLNKLEPWDIQERCKIGTAPQNDWYFFSHKDKKYPAGTRTNRATAAGFWKATGRDKVIYGTGKRVGMRKTLVFYKGRAPHGQKSDWIMHEYRLDDNPSETNVSNVMGEAAQEDGWVVCRIFKKKNLNKTLDRAMSSSPITADTRNQTLSSCNEGSLDQMLHYMGSTCKEENEADNSARYLWPIDTAINHVHHDNRFMELPSLESPNSTSSLNFYQSMITENEGSITNQVSYPLDSGLNNWVALDSLVASQINGQAETSRQSACFPNDPTMTYCTPTDLHHDLQFPTLRSSFSFPSNRSYHETQDYNSEIDLWNFSSRSSSDPQWHLPNTSV
Protein: Probable conserved membrane protein (O05456)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- ESX-2 secretion system protein eccD2
- ESX-2 secretion-associated protein EspG2
- Mycosin-2
- ESX-2 secretion system protein EccE2
- ESX-2 secretion system protein EccA2
- ESAT-6-like protein EsxC
Sequence:
MTNPWNDPNMLDDGAIGRGDPSVRHHFRDSVSDTMRITDLAAPRKIPPGTGWRKFVYSVSFHKINPGESPRERHYRNLQGRIRRHIRRQYVITVVSGKGGVGVTTMAACIGGVFRECRPENVIAIDAVPSFGTLADRIDESPPGDYAAIINDTDVQGYADIREHLGQNTVGLDVLAGNRTSDQPRPLVPAMFSAVLSRLRRTHTVIVIDTSPDLEHDVMKAVLQSTDTLVFVSGITADRSRPVLRAVDYLRAQGYHELVSRSTVILNHTDSITDKDALAYLTERFTKVGAIVEAMPFDPHLAKGGIIDTVHELNKKSRLRLFEITAGLADKYVPDAERAAQ
Protein: Ataxin 1b (Ataxin-1 isoform X1) (Ataxin-1a) (Q1L966)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Ataxin-1-like
- Recombination signal-binding protein for immunoglobulin kappa J region b
- Recombination signal-binding protein for immunoglobulin kappa J region a.
- Ataxin 1b
- Recombination signal-binding protein for immunoglobulin kappa J region-like.
- GTP-binding protein 1
- Nuclear protein 1a.
- Matrix metallopeptidase 30.
- Protein capicua homolog
- Capicua transcriptional repressor a.
Sequence:
MKSNQERSNECLPPKKREIPASTLPSEEKPMVMAPANESQRGGNLAWLASLASGHDKGRLHTSTSAESDGPQYKPLSAMAESTPSSSTHSTRALSAVTTIPAVYTSPLSHSPSAIQYTPLPHNIHFINPPYSAPYAGYISPLAPPLAATTTTQREIYASSSSSPASKIDQHHQLGRPQGLVTTDNTSSPHSTQYVQIAGSPLSISPRTVSSPHTHMPLHLHPHHTLPLSGPSQVLVPYTESLLPKREEMRTRELLNGELEKDRRFGPSSESSAGKQGSTAKGGSSAQQHQIHQQQSPRHFEARHVVLPAEYTQDSTAMRTSLVLVPNNHSSTSADSGGASDKLPPSTSHHEKGGICAGKPVSRSSSLSSSLSFALPPPPVDNLKGAVPAQSPHAVIQTTLNSTESLSLSLPSTNFYSTQQPIIGYFAGTGHQQPLSYHTTLPQHLVIPGTQPVIIPVSGTEATATSTAALPHAFVTSTAPKVETFESPAPYPHPATAMVQAQLHLPVVPATAGLLTTPPPPSAPSMPPYFTKGSIIQLADGELKRVEDLKTEDFIQSAEISNELKIDSSTVERIDSSHTANFAIIQFAVGAQRSQVSVEVLVEYPFFVFGQGWSSCCPDRTTQLLELPCTKLSVGDVCISLTLKNLRNGSIKKSQGQVLDAPALGPPLKSPKALSSGARGGVRHTEQENGLGQCADQGSRGGQGNRENGELRFGERDNCKAPTLTESETSSKPTGRKRRWSAPEGRKVENPEGEPPLTFPKPSFIPQEVKISIEGRSNIGK
Protein: Endolysin (EC 3.5.1.-) (LysSPP1) (Putative N-acetylmuramoyl-L-alanine amidase) (O48471)
Organism: Bacillus phage SPP1 (Bacteriophage SPP1)
Function: Endolysin that degrades host peptidoglycans and participates with the holin protein(s) in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin(s) has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
Subcellular location: Host cytoplasm. Note=The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane. {ECO:0000305}.
Interaction partners:
Sequence:
MSKLVWLDAGHGGKDSGAAANGIKEKDIVLKIVKKVKSILTSRYEVAVKLTRDSDVFYELIDRARKANAAKADLFVSVHINATPGGKGFETYRYVKTSASSSTGQQQKVLHDAIYKRIKKYGIKDRGEKAADLSVLRNTSMPAVLTENLFIDNKDEAALLKKDSFLNDVAEGHAEGIAEILNLKKKSGGSAPKKEDKPSSGKTKMVIVKDNPDGFLWVYNKADWNARYKKVKPDEAFTIDKTVTVNGSKMYKLKSGLYITAASKYVTVKEK
Protein: Uncharacterized protein YcfL (P75946)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Purine nucleoside phosphoramidase
- Penicillin-binding protein activator LpoB
- UPF0227 protein YcfP
- Thiamine kinase
- Beta-hexosaminidase
- UPF0225 protein YchJ
Sequence:
MRKGCFGLVSLVLLLLVGCRSHPEIPVNDEQSLVMESSLLAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAHSAVTLYGSANFLGAHKVRLYLYL
Protein: Heart- and neural crest derivatives-expressed protein 2 (Class A basic helix-loop-helix protein 26) (bHLHa26) (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (P61296)
Organism: Homo sapiens (Human)
Function: Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor GATA-4
- Homeobox protein Nkx-2.5
- T-box transcription factor TBX5
- Runt-related transcription factor 2
- Myocyte-specific enhancer factor 2C
- T-box transcription factor TBX20
- Myocardin
- Transcription factor E2-alpha
- Paired mesoderm homeobox protein 2B
- Nebulette
Sequence:
MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
Protein: Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (N-acetyltransferase type 1) (NAT-1) (P50294)
Organism: Mus musculus (Mouse)
Function: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Isoniazid, 2-aminofluorene and anisidine are preferred substrates for NAT-1. No activity with p-aminobenzoic acid (PABA) nor SMZ.
Subcellular location: Cytoplasm.
Interaction partners:
- Cytochrome P450 1A2
- Cytochrome P450 2E1
- Xanthine dehydrogenase/oxidase
- Arylamine N-acetyltransferase 2
- Carboxylesterase 1C
- Arylamine N-acetyltransferase 3
- Carboxylesterase 1D
- Carboxylesterase 1E
- Carboxylesterase 1F
- Myeloperoxidase
Sequence:
MDIEAYFERIGYKNSVNKLDLATLTEVLQHQMRAVPFENLNMHCGEAMHLDLQDIFDHIVRKKRGGWCLQVNHLLYWALTKMGFETTMLGGYVYITPVSKYSSEMVHLLVQVTISDRKYIVDSAYGGSYQMWEPLELTSGKDQPQVPAIFLLTEENGTWYLDQIRREQYVPNEEFVNSDLLEKNKYRKIYSFTLEPRVIEDFEYVNSYLQTSPASVFVSTSFCSLQTSEGVHCLVGSTFTSRRFSYKDDVDLVEFKYVNEEEIEDVLKTAFGISLERKFVPKHGELVFTI
Protein: Heat shock protein 90-1 (AtHSP90.1) (AtHsp90-1) (Heat shock protein 81-1) (Hsp81-1) (Heat shock protein 83) (P27323)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as a holding molecular chaperone (holdase) which stabilizes unfolding protein intermediates and rapidly releases them in an active form once stress has abated. Functions as a folding molecular chaperone (foldase) that assists the non-covalent folding of proteins in an ATP-dependent manner. Molecular chaperone involved in R gene-mediated disease resistance. Required for full RPS2-mediated resistance through interaction with RAR1. Possesses probably ATPase activity.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Protein SGT1 homolog B
- Protein SGT1 homolog A
- Peptidyl-prolyl cis-trans isomerase FKBP62
- Cysteine and histidine-rich domain-containing protein RAR1
- Heat shock 70 kDa protein 4
- Heat stress transcription factor A-2
- Peptidyl-prolyl cis-trans isomerase CYP40
- Heat shock 70 kDa protein 8
- Peptidyl-prolyl cis-trans isomerase FKBP65
- Chaperone protein ClpB1
Sequence:
MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQPELFIRLVPDKSNKTLSIIDSGIGMTKADLVNNLGTIARSGTKEFMEALQAGADVSMIGQFGVGFYSAYLVAEKVVVTTKHNDDEQYVWESQAGGSFTVTRDVDGEPLGRGTKITLFLKDDQLEYLEERRLKDLVKKHSEFISYPIYLWTEKTTEKEISDDEDEDEPKKENEGEVEEVDEEKEKDGKKKKKIKEVSHEWELINKQKPIWLRKPEEITKEEYAAFYKSLTNDWEDHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDTRKKLNNIKLYVRRVFIMDNCEELIPEYLSFVKGVVDSDDLPLNISRETLQQNKILKVIRKNLVKKCIEMFNEIAENKEDYTKFYEAFSKNLKLGIHEDSQNRGKIADLLRYHSTKSGDEMTSFKDYVTRMKEGQKDIFYITGESKKAVENSPFLERLKKRGYEVLYMVDAIDEYAVGQLKEYDGKKLVSATKEGLKLEDETEEEKKKREEKKKSFENLCKTIKEILGDKVEKVVVSDRIVDSPCCLVTGEYGWTANMERIMKAQALRDSSMSGYMSSKKTMEINPDNGIMEELRKRAEADKNDKSVKDLVMLLYETALLTSGFSLDEPNTFAARIHRMLKLGLSIDEDENVEEDGDMPELEEDAAEESKMEEVD
Protein: Tubulin gamma chain (Gamma-tubulin) (Q55AR3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000305}.
Interaction partners:
- Spindle pole body component 97
- Spindle pole body component 98
- DNA-directed RNA polymerase I subunit rpa2
- Clathrin heavy chain
- WD40 repeat-containing protein
- Nicotinate phosphoribosyltransferase
- Kinesin-related protein 2
- propionyl-CoA carboxylase
Sequence:
MPREIITLQVGQCGNQIGSEFWKQLCKEHGINAAGYLEEFAKPGIDRKDVFFYQSDDDHYVPRALLLDLEPRVIDSIKTSEYSGLYNQENIFVAEKGTGAGNNWANGYKQGESFYDDIFDMIDREADGSESLEGFLLTHSISGGTGSGMGSYILERLNDRFPKKIIQTYSVFPDDSSVVVQQYNSVLTLKRLIENADSTVVLDNNALHRIVGENLRIDQPTMDQTNSLVSTVMSASTTTLRYPGYMNNDLVGMLASLIPTPKCHFLITGYTPLSIDRQTESVRKTSVLDVMRRLLQPQNIMVSAPTKTGKYISILNIIQGDVDPTQIHNSLQRIREKRMATFIDWGPASIQIALSKKSPYIKSSHKVSGLMLANHTSVNHLFSHIIQQYDKVRKKQAFLANYTRESGEILQEFDIAREMLDDLVQEYKAAEQSDYINYHMNKEFNNNNNNNNGNPQYQYGTV
Protein: Iron uptake protein A2 (Iron deficiency-induced protein A) (PP2) (Q55835)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Probably part of a periplasmic ABC transporter complex futA1A2BC (TC 3.A.1.10.2) involved in Fe(3+) ion import (ferric iron). This protein and futA1 (slr1295) are subunit proteins that have redundant or overlapping substrate-binding functions (Probable). The differing subcellular locations of futA1 (predominantly thylakoid lumen) and futA2 (predominantly periplasmic) suggest they may fulfill different roles.
Subcellular location: Cellular thylakoid membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Lumenal side {ECO:0000305}. Periplasm. Note=Binds Fe(3+) in the periplasm.
Interaction partners:
- Iron utilization protein
- ABC transporter
- Sll0238 protein
- Sll0237 protein
- ABC transporter
- Iron uptake protein A1
- Iron
Sequence:
MTTKISRRTFFVGGTALTALVVANLPRRASAQSRTINLYSSRHYNTDDALYDAFGEVNLIEASAEELIERIQSEGANSPGDILFTVDAGMLWRAEQAGLFQPVRSGKLNERIPENLRHPDGLWYGFTQRARVLYYSRDRVNPADLSTYEALADPQWRGKILVRPSSNVYNLSLTASRIAIHGEPETRRWLQGLVGNFARQPEGNDTAQIRAIAAGIGDVAIANSYYYIRLQKSTDPADQEVVEKVSLFFPNTGSGERGTHVNVSGAGVLKNAPNRDAAIAFLEYLASDDAQRYFAEGNNEYPVIPGVPIDPVLAAHGQLKGDPLNVSNLGRYQPDSARLMNEVGWQ
Protein: MYO9B protein (Q8WVD2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
DKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPLKLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTVAAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPPARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG
Protein: Putative heat shock protein HSP 90-beta-3 (Heat shock protein 90-beta c) (Heat shock protein 90Bc) (Q58FF7)
Organism: Homo sapiens (Human)
Function: Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MPEEVHHGEEEVETFAFQAEIAQLISLIINTFYSNEEIFLQELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLALVDTGIGMTKADLINNLRTIAKSGTKACMEALQAEKLVVITKHNDDEQYAWESSAGGSFTVHADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEQDKEISDDEAEEEKGEKEEEDKDDEEKPKIKDVGSDEEDDSKEYGEFYKSLTSDWEDHLAVKHFSVEGQLEFRALLFSPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIHGVVDSEDLPLNISREMLQQSKILKYVSHMKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKEKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNHIYHMIKLGLGTDEDEVAAEEPSDAVPDEIPPLEGDEDASRMEEVD
Protein: IQ motif-containing GTPase-activating protein 1 (Ras GTPase-activating-like protein IQGAP1) (F6WBH7)
Organism: Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Interaction partners:
Sequence:
MSVSEEVDGLVRPHYGSVLDDERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEELPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYNATGLHFRHTDNVIQWLNAMSEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVEFTAEEINFMKSELEKYGIQMPAFGKIGGILASELSVDEAALHAAVIAINEAIDRGVPEETFTALQNPNAMLVNLNKPSATVYQNTLYQAKQHKTENARKRLITDNAGGERDVYEELLTQAEVQGNVNKVNLQTGIEYVDQALETGDPQILFEALSSPSLALRMLQQENAEWYLKTLQAEKQQKQESGLNEPLQKEELQAGVDAGNSAAQKSQRKLTAVIRINNAIRKGVVEETVKELMNPDAQLPEVYPFAGSLYQNELATLQQQSPEGNLTHPELLVAVEMLSSVALINRALDAGDVSTMKKQLISPVTGLMDVDDENLQRYIDELIRMKQQAREEGIEFITWNDIQGCVTQVNLTVQEEHARIMAIGLINEALDEGDAKKTLQALQLPAAKLEGVQPNVAQHYQDTLVRAKREKAQETKDESAVLWLDEIQDGIICSNKETEDAQKFSLGILAINEAVKQGDSAHTLNTLRSPDVGLYGVTGECAQAYQNELAEVQKKKMEAGDNGSEWVQHWVKGGYLYYFNLSTNEGRWVEPQGFAQNSSQLSKEDIQTTISGVSAAYNREQLWLANETLITKLQARCRGYLIRQKFNARLKFLREQIPAINCIQAHYRGQKQRKEYKDRLQYLNDHSDEVVKIQSYTRMHQARKRYRDRLQYFRDHINDIVKIQAFIRANKARDDYKTLINAENPPMVVVRKFVHLLDQSDQDFQEELEVMKLREEVVTLLRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLADMMMLNKQRGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILSPVVKEIMDDKSLNIKTDPVDIYKAWVNQMESQTGEASKLPYDVTPEQAMSHEEVRSRLDASVKNMRTVTDKFLVAIISSVDKIPYGMRYIAKVLKDTLHEKFPDAGEDELLKIVGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSAINEYLSQSYQKFRRFFQSACEVPELEDKFNVDEYSDLVTVTKPVIYISIGEIVNTHTLLLDHQDAVAPEHNDPIHELLDDLGEVPTIESLIGEGPGSAGDTNMDSLAKTEVSLTLTNKFEILGDENAEKDAKTIMLNTKRLIVDVIRFQPGETLAEILETRATNEQESDHLRAMQRRAMRDAKTPDKMKTAKSLRQDSNLTLQEKKDKIKAGLKKLEEMGLVNPDNRYQDLINDIAKDIRNQRRYRQRRKAELVKLQQTHTALNSKALFYEEQVDYYKSYIKTCMDNLASNRKLSKKPGQAKGKKSKKISLKYSAARLHEKGVLLEIEDLQANQFKNVIFEIAPTDEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLINKKFYGK
Protein: Dynein light intermediate chain (Q8IR93)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU366047}.
Interaction partners:
Sequence:
MTRLGVWVLDGDPGHTNLLHYALNETNYAHTLVILTVSMTQPWGWLEQLNHWIKVLGQHIDSLQLDAKEKEAARQRLTTTWQSYCEVGDDLDPGSPVKRTMRNNSIDEDDLLPLTEDALITNLGLDIVVVVTKTDYMTTLEKEYEYRDEHFDFIQQWIRNFCLRHGTSLFYTSVKEDKNCDVLYKYLTHRIYGLPFRTPALVVEKDAVLIPAGWDSLKKISILYENMHGVKAENPYTDIIKSPPTRKAVSNREAEVQTEDEQAFLARQQEILKQGDQVRGESPLRSQGVGSNKSGPRTPGTTGQSSPKKIDPKLTPATPGAEGVLANFFNSLLHKKSGSPGTGGPGGAGNPAGPGRTANGTDAVMTPEKLAVRTDAAAELDRLSRSVKKEIDMSQSEC
Protein: N-carbamoylputrescine amidase (EC 3.5.1.53) (Nitrilase-like protein 1) (Q8VYF5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in polyamine biosynthesis. Catalyzes the hydrolysis of N-carbamoylputrescine to produce putrescine and ammonia.
Interaction partners:
- Agmatine deiminase
- Spermidine synthase 2
- Spermidine synthase 1
- Spermine synthase
- Probable polyamine oxidase 4
- Polyamine oxidase 2
- Polyamine oxidase 3
- Agmatine coumaroyltransferase
- Arginine decarboxylase 1, chloroplastic
- Arginine decarboxylase 2
Sequence:
METEGRRREVVVSSLQFACSDDISTNVAAAERLVREAHAKGANIILIQELFEGYYFCQAQREDFFKRAKPYKNHPTIARMQKLAKELGVVIPVSFFEEANTAHYNSIAIIDADGTDLGIYRKSHIPDGPGYQEKFYFNPGDTGFKVFQTKFAKIGVAICWDQWFPEAARAMVLQGAEILFYPTAIGSEPQDQGLDSRDHWRRVMQGHAGANVVPLVASNRIGKEIIETEHGPSQITFYGTSFIAGPTGEIVAEADDKSEAVLVAQFDLDMIKSKRQSWGVFRDRRPDLYKVLLTMDGNL
Protein: Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha] (P26350)
Organism: Mus musculus (Mouse)
Function: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Subcellular location: Nucleus.
Interaction partners:
- Kelch-like ECH-associated protein 1
- Histone H1.0
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL30
- High mobility group protein B1
- GTP-binding nuclear protein Ran
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL15
- Small ribosomal subunit protein eS19
- Peptidyl-prolyl cis-trans isomerase A
Sequence:
MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAQNEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAEAPTGKRVAEDDEDDDVDTKKQKTEEDD
Protein: Insulin-like growth factor-binding protein 1 (C9J6H2)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MSEVPVARVWLVLLLLTVQVGVTAGAPWQCAPCSAEKLALCPPVSASCSEVTRSAGCGCCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGSPESPESTEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQN
Protein: Acetylcholinesterase 1 (ACE-1) (AChE 1) (EC 3.1.1.7) (P38433)
Organism: Caenorhabditis elegans
Function: Rapidly hydrolyzes acetylcholine and releases choline into the synapse (Probable). It can hydrolyze propionylcholine and butyrylthiocholine in vitro (Probable).
Subcellular location: Synapse {ECO:0000250}. Secreted {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=May be secreted or membrane associated via a non-catalytic subunit.
Interaction partners:
- Carboxylic ester hydrolase
- Carboxylic ester hydrolase
- Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 1
- Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 2
- Choline kinase A2
- Putative choline kinase B3
- Choline kinase B2
- Choline kinase B1
- Vesicular acetylcholine transporter unc-17
- Choline O-acetyltransferase
Sequence:
MRNSLLFFIFLPSTILAVDLIHLHDGSPLFGEEVLSQTGKPLTRFQGIPFAEPPVGNLRFKKPKPKQPWRIPLNATTPPNSCIQSEDTYFGDFYGSTMWNANTKLSEDCLYLNVYVPGKVDPNKKLAVMVWVYGGGFWSGTATLDVYDGRILTVEENVILVAMNYRVSIFGFLYMNRPEAPGNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHMLSPKSAPYFHRAIIQSGSATSPWAIEPRDVALARAVILYNAMKCGNMSLINPDYDRILDCFQRADADALRENEWAPVREFGDFPWVPVVDGDFLLENAQTSLKQGNFKKTQLLAGSNRDESIYFLTYQLPDIFPVADFFTKTDFIKDRQLWIKGVKDLLPRQILKCQLTLAAVLHEYEPQDLPVTPRDWINAMDKMLGDYHFTCSVNEMALAHTKHGGDTYYYYFTHRASQQTWPEWMGVLHGYEINFIFGEPLNQKRFNYTDEERELSNRFMRYWANFAKTGDPNKNEDGSFTQDVWPKYNSVSMEYMNMTVESSYPSMKRIGHGPRRKECAFWKAYLPNLMAAVADVGDPYLVWKQQMDKWQNEYITDWQYHFEQYKRYQTYRQSDSETCGG
Protein: Transmembrane protein (Q38D30)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRVTLEERDLHIAFSVSLATIGLVFLVQHVASTVSRLPSWFINLRWHYISLICLPVCLLVSLSLSSISWFLVSAGAGLALVSGVRTWERGATTFLFCFLLAGQCLEQLSHTVHVTLPPKARTWTSRYRGQIALWPTGEATGPEHLLVMYNDVTLTRQPCSGAVAGTIPTQAGAVTRQLGMRRHTLVSFATNTRIGSMESCLGDGANGGFLPLHQVALLGESGRLEDVTLRCGLPSSARDGNSNGKTFSRCLTLDASTTFENVTVEFYADGNFKAVVSILHADKCADALSQLQAVGKSILKDEIDVLLCLPSAVSYRFSKLVGDPTLVPTALRAEVPYFFRCVWYLPMAVRNIPEGAAFIADRVVIPIAATVVANSLAFVQTIIWTCWNLMPDVLQLLEDVGVFVTGAYCRAVKGTNSTLCAKSLLEHAEDQRFQLGVRSVDCVFETVRLVLDALELVPGLWRVLLWTLRAEWHLVLYCLNIVQVILTVVVRWPLQTLYGALQLTLSWMLQTLSLFFLDYDLSRIGDALCSPLAYLYRLQKELLAAEAQAAWGLLWWFFSGVCRMVNVFFATVCAVCNGLFCVVSLYTGTTFCTHSFVALIQTAIVLIAMRNELHDIATRDGTGYTSFVGRWPGGKYMVMLTLFAKLHSVVLLRYTVAHTVLIFTLFGLSVVGVLSKLYNLTLYIAFPWVSTTVFLEFFTADPRWSTVAWVSAAKGLVAILLDRTIGDFTAYLVGEVFFVLGVVFTGAAFVWGCQKELPLLALRVLLRLPLDSSSESSTTGAKLNTTPQPDVGRAVFLDDATGAEMTKGEIMLPDVVEVVDDTGKEEATECNKDVQ