wanglab/gogpt-training-data huggingface dataset:
Protein: GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I) (P51601)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.
Interaction partners:
- Folic acid synthesis protein FOL1
- Vacuolar protein sorting-associated protein VTA1
- Dihydrofolate synthetase
- GTP cyclohydrolase-2
- Inosine triphosphate pyrophosphatase
- Probable folylpolyglutamate synthase
- Repressible alkaline phosphatase
- Nucleoside diphosphate kinase
- Dihydrofolate reductase
- Folylpolyglutamate synthase
Sequence:
MHNIQLVQEIERHETPLNIRPTSPYTLNPPVERDGFSWPSVGTRQRAEETEEEEKERIQRISGAIKTILTELGEDVNREGLLDTPQRYAKAMLYFTKGYQTNIMDDVIKNAVFEEDHDEMVIVRDIEIYSLCEHHLVPFFGKVHIGYIPNKKVIGLSKLARLAEMYARRLQVQERLTKQIAMALSDILKPLGVAVVMEASHMCMVSRGIQKTGSSTVTSCMLGGFRAHKTREEFLTLLGRRSI
Protein: Procyclin associated gene 3 (Q581F4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFRKSSELEGKCSSSPFVRRDSHTEASTKQAATLLLTFWFILFPYFSVGVFLLPPLGIGHSHMKALASAAKGGSVWYFLWRHLSSFPFRPPLFPWRKASGTVLPDDLCPVRSIMNNSYKSVCRYGGGYFPNRFGCFYYFVGRFKVGNSVHFQKNCDSYIWFYMEGGRAENVYVLAWMSRKINSSFRVFSLHYVIYGLAFRFV
Protein: Tumor necrosis factor ligand superfamily member 8 (CD30 ligand) (CD30-L) (CD antigen CD153) (P32972)
Organism: Mus musculus (Mouse)
Function: Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Subcellular location: Membrane; Single-pass type II membrane protein.
Interaction partners:
- Tumor necrosis factor receptor superfamily member 8
- Tumor necrosis factor receptor superfamily member 4
- CD27 antigen
- Tumor necrosis factor ligand superfamily member 4
- Tumor necrosis factor ligand superfamily member 15
- Tumor necrosis factor receptor superfamily member 9
- Tumor necrosis factor receptor superfamily member 5
- Tumor necrosis factor
Sequence:
MEPGLQQAGSCGAPSPDPAMQVQPGSVASPWRSTRPWRSTSRSYFYLSTTALVCLVVAVAIILVLVVQKKDSTPNTTEKAPLKGGNCSEDLFCTLKSTPSKKSWAYLQVSKHLNNTKLSWNEDGTIHGLIYQDGNLIVQFPGLYFIVCQLQFLVQCSNHSVDLTLQLLINSKIKKQTLVTVCESGVQSKNIYQNLSQFLLHYLQVNSTISVRVDNFQYVDTNTFPLDNVLSVFLYSSSD
Protein: NEDD4 binding protein 2 (F8VQG7)
Organism: Mus musculus (Mouse)
Interaction partners:
- NADH dehydrogenase 1 beta subcomplex subunit 7
Sequence:
MDCLLELSATDAKGAESSAQTSGDRDSKPGAAGNSVMETCHPEGEGEDSKLDSFLDMQLTEDLDSLIQNAFEKLNSPPDDQVYPFSPLQDANSFNDPSTFMNSDSSGMTSLLSVQSTSSNSETLKSSASLPGSNPPTSHSVLNAPESCAKLALEGGYSEGSPLSSSGNPTNGSVRGCGNFSQRQKDLSESECPSAQHSQALADLGNSDPQAPSTHPLHNSGSDLPGTDGDQKSASAPDVFVPSEGFNFKPHKHPELPPKGKDMNYCPVLTPLPLLLPPPPPPPIWNPMIPAFDLFQGNHGFVAPVVTTAAHWRPVNYTFPPPIISHNSPTKVWRGGEGASAYQVQEAPASQPVRKKATSFVGLVLVLLRGLPGSGKSFLARTLQEDNPGGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKISRMLEHYQRFVSVPIIMSSSDPEKTERIELCAYASDDSPRDSEAISSAKEDSVSSASPKHSELTEEKTLEVATQAVLSVRDPQLPCPGLNRGRKELGDVSHGGHNPFFQEAPSTYFPNPESKGQATDRSEEEQEMVSEKEHCEADAWRPAGGASSDGRCADDNQEACGSAGAAALPGETPSPPEMLEERTAGKKKTIGKQKGKSSLEKIPKQELSNFVGDWPVDKTISQRTKRNRKTEKGLSVQSDKKGNLPQSHKVLDARVSVNTDPVQPQGSSHGNDDLSEVPSSYHYDPYRSTEQSSLSAVSDWPSSASLAPREHRPRMPKADLSEPSVEFGTNDNLGEIPLYPAHEAYWGTSPEELKTLSSSLRSSEMLPSQTAPEHHPTSLNPLAHSQHALPLTFPSSAAALPGVVGPRSLTEFPVGVSGIVSGVDTGTCTQTEPQDFALLWKIEKNKINVSDSVRVLTGRLDGFKPKDFTLNRKVNVQETIPYRVMHDKSTFVEESELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTAVESSPKSYSESQVGPFSMGLDLKEIISHRGTSEGSNSSVSEFSPGIGIRNTSARSAGNPGKGTSEQEGRRAMNPENPELITRVFPNAAVKVKSNNETLPDRQAELPGAYTFKQPLSLTPRSYIPKDVSEIEKNLVMTETRDNMHSFLNLSDIINSATSTSNPELNEDVYLTGSLEVKKNENLPKDYVKFANMEEFINEDKQEMEKNLMPGSGWSAGVSEEGKAEVLTPTPVTATSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWRESVMERQRQEEVSRGKRTQDPLLAGHTGLDNFEQKSSQKTGKRLLKTLAAPETLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHSYSLENTVQFLNCVLEGDPVKTVVAQECVHQNENNTYTAQKSKEKKAKKPKEAEDSPGDPSFQDFEYPEYDDYRAEAFLHQQKRMECYSKAKEAYRMGKKNVATFYAQQGSLHEQKMKEANHLAAVEIFEKVNASLLPQNVLDLHGLHVDEAIEHLTAVLQQKTEEFKQSGGKPYLSVITGRGNHSQGGVARIKPAVIKYLTSHSFRFSEIKPGCLKVMLK
Protein: Uncharacterized protein (A0A0H2UN91)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MVLRGVPMSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFALVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWKSVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSASAGPTRYQE
Protein: Alcohol dehydrogenase transcription factor Myb/SANT-like family protein (Q9LV59)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Homeodomain-like superfamily protein
- Trihelix transcription factor GTL2
- Trihelix transcription factor GT-2
- LOB domain-containing protein 31
Sequence:
MGDSEDETGYPKKFYSLNRQNHPMYSRPIPKRHAYYNEEEDEDEVEGEEEDPQGGYIRGNERFQKRQKPNKVVSGFEFAGPSDAKVAYDWREQEAFVLLEVWGDRFLQLGRRSLRNEDWNEVAEKVSEELRMEKSETQCRRMIDDLKRKYRKEKIKVEKSGLGSSKWSFFNKLDMLLCVSPKSDLGLACGVDSGEFVFMNTKVYLDKSNGFDEMMDSPGDSEEEEDEDDEVEYERKKVNDAASYKMLADSVERFGKVYEKMEKSKKEQMKELEKMRADFQRDLELQKKQIVDRAQSEIARLREEEENHHGGGDDDESEDEEMENDSDVNLSDE
Protein: O-phosphoserine--tRNA(Cys) ligase (O-phosphoserine--tRNA ligase) (EC 6.1.1.27) (Non-canonical O-phosphoseryl-tRNA(Cys) synthetase) (O-phosphoseryl-tRNA(Cys) synthetase) (SepRS) (Q59054)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
Interaction partners:
- O-phospho-L-seryl-tRNA:Cys-tRNA synthase
- Phenylalanine--tRNA ligase beta subunit
- Type-2 serine--tRNA ligase
- Uncharacterized protein MJ1481
- Glutamate--tRNA ligase
- Aspartate--tRNA
- Uncharacterized protease MJ1657
- Histidine--tRNA ligase
- Uncharacterized ATP-binding protein MJ1659
- Uncharacterized protein MJ1658
Sequence:
MRFDIKKVLELAEKDFETAWRETRALIKDKHIDNKYPRLKPVYGKPHPVMETIERLRQAYLRMGFEEMINPVIVDEMEIYKQFGPEAMAVLDRCFYLAGLPRPDVGLGNEKVEIIKNLGIDIDEEKKERLREVLHLYKKGAIDGDDLVFEIAKALNVSNEMGLKVLETAFPEFKDLKPESTTLTLRSHMTSGWFITLSSLIKKRKLPLKLFSIDRCFRREQREDRSHLMSYHSASCVVVGEDVSVDDGKVVAEGLLAQFGFTKFKFKPDEKKSKYYTPETQTEVYAYHPKLGEWIEVATFGVYSPIALAKYNIDVPVMNLGLGVERLAMIIYGYEDVRAMVYPQFYEYRLSDRDIAGMIRVDKVPILDEFYNFANELIDICIANKDKESPCSVEVKREFNFNGERRVIKVEIFENEPNKKLLGPSVLNEVYVYDGNIYGIPPTFEGVKEQYIPILKKAKEEGVSTNIRYIDGIIYKLVAKIEEALVSNVDEFKFRVPIVRSLSDINLKIDELALKQIMGENKVIDVRGPVFLNAKVEIK
Protein: Putative outer membrane protein BBA03 (Q44849)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Subcellular location: Cell outer membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKKTIIVFIILAFMLNCKNKSNDAEPNNDLDEKSQAKSNLVDEDRIEFSKATPLEKLVSRLNLNNTEKETLTFLTNLLKEKLVDPNIGLHFKNSGGDESKIEESVQKFLSELKEDEIKDLLAKIKENKDKKEKDPEELNTYKSILASGFDGIFNQADSKTTLNKLKDTI
Protein: Transcription factor RelB (I-Rel) (Q01201)
Organism: Homo sapiens (Human)
Function: NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer in a CRY1/CRY2 independent manner. Increased repression of the heterodimer is seen in the presence of NFKB2/p52. Is required for both T and B lymphocyte maturation and function.
Subcellular location: Nucleus {ECO:0000269|PubMed:20873783}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20873783}. Note=Colocalizes with NEK6 in the centrosome.
Interaction partners:
- Nuclear factor NF-kappa-B p100 subunit
- Transcription factor p65
- Nuclear factor NF-kappa-B p105 subunit
- Proto-oncogene c-Rel
- NF-kappa-B inhibitor epsilon
- NF-kappa-B inhibitor alpha
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- NF-kappa-B inhibitor beta
- B-cell lymphoma 3 protein
- Tumor necrosis factor receptor superfamily member 5
Sequence:
MLRSGPASGPSVPTGRAMPSRRVARPPAAPELGALGSPDLSSLSLAVSRSTDELEIIDEYIKENGFGLDGGQPGPGEGLPRLVSRGAASLSTVTLGPVAPPATPPPWGCPLGRLVSPAPGPGPQPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGMPDVLGELNSSDPHGIESKRRKKKPAILDHFLPNHGSGPFLPPSALLPDPDFFSGTVSLPGLEPPGGPDLLDDGFAYDPTAPTLFTMLDLLPPAPPHASAVVCSGGAGAVVGETPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNHYREAAFGGGLLSPGPEAT
Protein: Importin N-terminal domain-containing protein (Q38FR1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MQTSSVSEVDCLAEQMYSSPDPSIRQRAQASLEQLTKAEADQSIICAILQQSNNQYALLFMSQCLVLWFKAVRKWISEEEKQNVIVVHCGGCVKRALENGAPKHVVSALLSAYAKLTKLAFEADPLLEGAVNYPIELLRHEADGTNMQLLGLMMLNALVVEFSKYDSSRSKTYLGFVAHRHCSGNFNEKCLLNILVEALKLLEKLTVNTPHITEIVKLVENCFSFDFRAIMVDDTEDLPFVHFPCAWKPTILSDQTLQTLWGQHAALPHPHCASLLSAISNICGTYRSFFETVEERLQYIEFTLTKLIQVTMLQDGRLKIPRYIETLAEAFRRVVLSLGYRELRQVAVFEQWVTAFQSISVDVLSITFGQEGSFSTATAVMAFWVALTTSKRRSYSEQCPQDIEVAVLPVLRAFLVARIHGADASGGDSFSLEDADGGLAEAVLAQSDAYANVCLLDPATYLGDFANYLNQQVGMSIFTSPLSTGWLFYIAGGVAWLVLFSMESSGIEPCSHVFAYARGCADHRRNHSGNPALFSSFVERGMLHFLTNMQSVITGARHGNLSAVVTNVFQDRGQLFQFVLDNVGHNLLRGPDSLDAVDIIRSSADVIVEACREAPPQLLRELSLELPPTSDLPLAQSEQTYKLRTNITKALWFVRSTGSYTRERMESYLSNVDFSMQRTVNNEVNSPSFIAGWVRDLRGACQALKEDQLSSLDFIDWFLSRYSVFVTIVDTAGDSPIVVTALMRFLCELVTPGKYGRLHISSSSNSAVGLMLFKHLCDLVEKVEKRTFSIDHLMALSSLSGSYNKVLKPWMLAMDIMKRCMEGSFVPFGAMLYYNDDTFERTTVDLLRKLALVGTNVFKEHGKFTVVAVDLLRLLVEENLYFCLRGLTGDELVGLINAVITVCEDVDTQSGVLVHGLGFLTFISGLVQEVRAIALSPSLRPTDTHGPDQSPAPFTQPFGSSRLSSPMPPVQQSIVSRPPRLATEVREHLARLLAPHDSVWQRLLSTAMNIIVFQDRAVNSSCAVVHHIFEAHPPFWFNYVEQLIMSFPEGKHATLREAFSVLTNAAETREKFFSEVFTLRQVLRRLGT
Protein: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) (Q61239)
Organism: Mus musculus (Mouse)
Function: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Interaction partners:
- Geranylgeranyl transferase type-1 subunit beta
- Protein farnesyltransferase subunit beta
- CAAX prenyl protease 2
- Geranylgeranyl pyrophosphate synthase
- CAAX prenyl protease 1 homolog
- Dehydrodolichyl diphosphate synthase complex subunit Dhdds
- Farnesyl pyrophosphate synthase
- Dehydrodolichyl diphosphate synthase complex subunit Nus1
- All trans-polyprenyl-diphosphate synthase PDSS1
- All trans-polyprenyl-diphosphate synthase PDSS2
Sequence:
MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILSQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDVYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV
Protein: Chromatin modification-related protein png1 (ING1 homolog 1) (O42871)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of a histone deacetylase complex responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Has a role in silencing of mating type genes.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Enhancer of polycomb-like protein 1
- SWR1-complex protein 4
- Histone acetyltransferase mst1
- Chromatin modification-related protein eaf3
- Protein AF-9 homolog
- NuA4 acetyltransferase complex subunit Tra2
- Chromatin modification-related protein vid21
- Actin
- Chromatin modification-related protein eaf6
- Actin-related protein 4
Sequence:
MADDTAYILSEYLQTLDNVPNETKHIFDEISVKEVAVHDIWKRIQAADSQIQSYIKSHGSLTPHPKEDALYSTIREEYQKAINIQNEKVQLADRARLGLTRHIKRLDDRLAKAGHGFTAAELLNAPDYYASSPYGGYSPSGASSARQTPAPSRSGASTAGRRRTSATTRGAIQNGVYHSPYTASLADSGSTRGQKVSNATATTQLETKADSTTPNEMVSEEDMEEDNEKYCFCQQGSYGQMVACDNANCEREWFHMECVGLKAPPEGTWYCEACRDQKLVDAK
Protein: Sensor protein EvgS (EC 2.7.13.3) (P30855)
Organism: Escherichia coli (strain K12)
Function: Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- DNA-binding transcriptional activator EvgA
- Aerobic respiration control sensor protein ArcB
- Signal transduction histidine-protein kinase BarA
- Sensor protein TorS
- Phosphotransferase RcsD
- Probable diguanylate cyclase DgcE
- Sensor protein PhoQ
- Sensor histidine kinase RcsC
- HTH-type transcriptional regulator YdeO
- Oxygen sensor protein DosP
Sequence:
MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRLSNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRVRGINADYLNLLKRALNIKLTLREYADHQKAMDALAEGEVDIVLSHLVTSPPLNNDIAATKPLIITFPALVTTLHDSMRPLTSPKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGHNDYFIGSNIITSSMISRYFTHSLNVVKYYNSPRQYNFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWLDTGNLAFLNKPLELTEHEKQWIKQHPNLKVLENPYSPPYSMTDENGSVRGVMGDILNIITLQTGLNFSPITVSHNIHAGTQLSPGGWDIIPGAIYSEDRENNVLFAEAFITTPYVFVMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIQVDNASAAFHKVKEGELDALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPPSEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKVIQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENSDSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASDNAVYICGWQDITETRDLINALEVEKNKAIKATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPEHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPVEISQQVATVEAKAEQPITLPEKLSILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLREQNSSLPIWGLTANAQANEREKGLSCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDIEALKNNTANDLQLMQEILMTFQHETHKDLPAAFQALEAGDNRTFHQCIHRIHGAANILNLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQKND
Protein: DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta') (P9WGY7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Interaction partners:
- Probable transcriptional regulator WhiB7
- RNA polymerase sigma factor SigA
- DNA-directed RNA polymerase subunit alpha
- ECF RNA polymerase sigma factor SigL
- RNA polymerase sigma factor SigB
- ECF RNA polymerase sigma factor SigH
- DNA-directed RNA polymerase subunit omega
- DNA-directed RNA polymerase subunit beta
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein bL17
Sequence:
MLDVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKAVEDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGGEREMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLYRELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVIRNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQPASGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLRPPVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGYPFVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQRGALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIITIVDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAYARTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVKVRSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGEDITGGLPRVQELFEARVPRGKAPIADVTGRVRLEDGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDGSERVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHLVREVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLIDRAEFEAENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNIAVQPTEEARAAAYTIPSYEDQYYSPDFGAATGAAVPLDDYGYSDYR
Protein: G2/mitotic-specific cyclin-B3 (Q10654)
Organism: Caenorhabditis elegans
Function: Could be involved at the G2/M (mitosis) transition (Probable). Interacts with the CDK1 and CDK2 protein kinases (Probable). G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis (Probable). Plays a role during oocyte meiosis II.
Subcellular location: Nucleus.
Interaction partners:
- Cyclin-dependent kinase 1
- WD repeat-containing protein fzy-1
- Cyclin-dependent kinases regulatory subunit
- Cyclin-dependent kinase 2
- G1/S-specific cyclin-D
- Cyclin-dependent kinase 4 homolog
- Fizzy-related protein homolog
- Aurora/IPL1-related protein kinase 2
- Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3
- Ribonucleoside-diphosphate reductase small chain
Sequence:
MMLRSQAKNVDLTSQADSRHQQKRKQAEQLDALKNPSEPAAKKQHSKGLTELRAHISGFKIDSAKRDPLGKSRTSRRDVENLPPQKSRYVDPCPHYDYDLEEAGNPDSISDYAQGIFDYYRHREVHFRVRKYLHKHPEVDVKTRAILIDWMVEIQETFELNHETLYNAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDRFSRDELLAMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEYAMVSQSRLAAAAFVLAMRMLDKNNEYEWNPVLEKYSGFTGEEVMPLVEHMNHILHFSKDKWAQLTSVRQKYSHEVFFHVASIPMLPDTLKVVDSHTYAPVPMLSYP
Protein: Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E) (Q8WWN9)
Organism: Homo sapiens (Human)
Function: Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocated with PSCD2 to the plasma membrane upon epidermal growth factor (EGF) stimulation. {ECO:0000250}.
Interaction partners:
Sequence:
MTSYMAIDGSALVPLRQKPRRKTQGFLTMSRRRISCKDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVERASECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTAQQASSSSPSLSGTSYSFSSLENTVKTPSSFPSSLSKERQSLPDTVNSLSAAEDEGQPITFAVQVHSPVPSEAGIHKALENSFVTSESGFLNSLSSDDTSSLSSNHDHLTVPDKPAGSKIMDKEETKVSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQRASPAPDDTDDTPQELKKSPSSPSVENSI
Protein: Myelin P2 protein (Peripheral myelin protein 2) (P02689)
Organism: Homo sapiens (Human)
Function: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Periaxin
- Ganglioside-induced differentiation-associated protein 1
- Cadherin-1
- Iron-sulfur cluster co-chaperone protein HscB
- Cadherin-17
- mRNA cap guanine-N
Sequence:
MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKNTEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKMKGVVCTRIYEKV
Protein: Probable permease of ABC transporter (Q9HVR8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363032}.
Interaction partners:
- Probable permease of ABC transporter
- ABC-type dipeptide transporter
- ABC-type dipeptide transporter
- Probable binding protein component of ABC transporter
- Dipeptide-binding protein
- Probable binding protein component of ABC transporter
- Tripeptide-binding protein
- Probable binding protein component of ABC dipeptide transporter
- ABC-type dipeptide transporter
- ABC-type dipeptide transporter
Sequence:
MLSFIARRLGLLIPTFFGVTLLTFALIRLIPGDPVEVMMGERRVDPQMHAEALHRLGLDKPLYQQYLDYVGNLAQGNLGKSIRTHEPVWNEFLTLFSATLELSFAAMLFAGTLGLLAGVVAALKRGSIFDHGVMTISLAGYSMPIFWWGLLLIMLFSVSLGWTPVSDRIGVLYEVEPKTGFMLIDTLLSDEEGAFLDAVRHLILPAIVLGTIPLAVIARMTRSAMLEVLREDYVRTARAKGLSPARVVFVHALRNALIPVLTVLGLQVGTLLAGAVLTETIFSWPGIGKWLIDAISARDYPVVQNGILLVATLVILVNFVVDILYGLANPRIRHQR
Protein: SP-RING-type domain-containing protein (Q380Z3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Small ubiquitin protein, putative
- SUMO-conjugating enzyme UBC9
Sequence:
MPTRSSVRHGEGVPLPPVLLFGSQANARSSRARAVAHGRVAVSSSDGMDDLLDVKRRLLRDMELAKRWDARSVELLQIHRKRAWDIAFGKPGGDDIEVSTMEFSLYCPYSRTAMYCPVRGETCLHVQCCDLESWITLFRKQRSLRDRRAPCPVCKGGVLVSSLEVDLWQLHVLSEMPQGTQKLVLNADGSYCSGDISRKQRKEEEVTEVLDMTQTSTQKVFTEEGTGVPTSVSSSAMPDAAFSKSEFIRVKRERHSLERLTDSPSLESDASLEATPDDDVVVVQYEAPAVEVRVLPSQLRLWTAHCPKCKQEMSCNSEDASPSQCGACGVEKSGWTLVRRFPNSHVTLELTGDGTILLRGVDAMAPYLWRAGFNREVFVDPPAGAHRWRGVGVWYSTFRFTRYELDFVEACCERVSRNEAVGNIPETPWLFRVPGQRRSERFSQLSLSGSGR
Protein: Tetratricopeptide repeat (TPR)-like superfamily protein (F4IJS7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MFVHKLRCYYGFLLKHFENCLLWLVAGNALNCLFIDSSGFQRYLGFGVTNLNGATVKSYKQEGFVIDERGKLKRFNRKKLSRKRCGSLRGRGWKYGSGFVDGIFPVLSPIAQKILSFIQKETDPDKVADVLGALPSTHASWDDLINVSVQLRLNKKWDSIILVCEWILRKSSFQPDVICFNLLIDAYGQKFQYKEAESLYVQLLESRYVPTEDTYALLIKAYCMAGLIERAEVVLVEMQNHHVSPKTIGVTVYNAYIEGLMKRKGNTEEAIDVFQRMKRDRCKPTTETYNLMINLYGKASKSYMSWKLYCEMRSHQCKPNICTYTALVNAFAREGLCEKAEEIFEQLQEDGLEPDVYVYNALMESYSRAGYPYGAAEIFSLMQHMGCEPDRASYNIMVDAYGRAGLHSDAEAVFEEMKRLGIAPTMKSHMLLLSAYSKARDVTKCEAIVKEMSENGVEPDTFVLNSMLNLYGRLGQFTKMEKILAEMENGPCTADISTYNILINIYGKAGFLERIEELFVELKEKNFRPDVVTWTSRIGAYSRKKLYVKCLEVFEEMIDSGCAPDGGTAKVLLSACSSEEQVEQVTSVLRTMHKGVTVSSLVPKLMAKSLTVN