wanglab/gogpt-training-data huggingface dataset:
Protein: Ankyrin 2 (A0A5F9ZH39)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MAHAAASIKKVREADLDEKEKNLERDRKKQRKIPRERMERKRKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIRRYVSSEGTEKEEIMVQGMPQEPVNIEEGDGYSKVIKRVVLKSDTEQSEDNNE
Protein: Minor capsid protein (O92837)
Organism: Simian virus 40 (SV40)
Subcellular location: Host endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004625}. Host nucleus {ECO:0000256|ARBA:ARBA00004147}. Virion {ECO:0000256|ARBA:ARBA00004328}.
Interaction partners:
Sequence:
MAVDLYRPDDYYDILFPGVQTFVHSVQYLDPRHWGPTLFNAISQAFWRVIQNDIPRLTSQELERRTQRYLRDSLARFLEETTWTVINAPVNWYNSLQDYYSTLSPIRPTMVRQVANREGLQISFGHTYDNIDEADSIQQVTERWEAQSQSPNVQSGEFIEKFEAPGGANQRTAPQWMLPLLLGLYGSVTSALKAYEDGPNKKKRKLSRGSSQKTKGTSASAKARHKRRNRSSRS
Protein: Glycerol-3-phosphate acyltransferase 5 (AtGPAT5) (EC 2.3.1.15) (Q9CAY3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Glycerol-3-phosphate acyltransferase, chloroplastic
- Glycerol-3-phosphate acyltransferase 9
- Omega-hydroxypalmitate O-feruloyl transferase
- Cytochrome P450 86A1
- Cytochrome P450 86B1
- Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4
- Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial
- Glycerol kinase
- Non-specific phospholipase C3
- Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Sequence:
MVMEQAGTTSYSVVSEFEGTILKNADSFSYFMLVAFEAAGLIRFAILLFLWPVITLLDVFSYKNAALKLKIFVATVGLREPEIESVARAVLPKFYMDDVSMDTWRVFSSCKKRVVVTRMPRVMVERFAKEHLRADEVIGTELIVNRFGFVTGLIRETDVDQSALNRVANLFVGRRPQLGLGKPALTASTNFLSLCEEHIHAPIPENYNHGDQQLQLRPLPVIFHDGRLVKRPTPATALIILLWIPFGIILAVIRIFLGAVLPLWATPYVSQIFGGHIIVKGKPPQPPAAGKSGVLFVCTHRTLMDPVVLSYVLGRSIPAVTYSISRLSEILSPIPTVRLTRIRDVDAAKIKQQLSKGDLVVCPEGTTCREPFLLRFSALFAELTDRIVPVAMNYRVGFFHATTARGWKGLDPIFFFMNPRPVYEITFLNQLPMEATCSSGKSPHDVANYVQRILAATLGFECTNFTRKDKYRVLAGNDGTVSYLSLLDQLKKVVSTFEPCLH
Protein: Spindle pole body component-like protein (F4J8J0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSYSEKTTVDPLLRDLDEKKESFRRNVVSLATELKQVRGRLVSQEQSFLKETITRKEAEKRGKNMEMEICKLQKRLEERNCQLEASASAADKFIKELEEFRLKLDTTKQTAEASADSAQSTKIQCSMLKQQLDDKTRSLREQEDRMTQLGHQLDDLQRGLSLRECSEKQLREEVRRIEREVTEAIAKAGIGGMDSELQKLLEDVSPMKFERMNRLVEVKDEEITKLKDEIRLMSGQWKHKTKELESQLEKQRRTDQDLKKKVLKLEFCLQEARSQTRKLQRFYCCCCFVMNGAQKGERRDMEIKEIRDLISEKQNLNNESWDKQKFWDNSGFKIVVSMSMLMLVVVSKR
Protein: valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (Q9VSR7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Elongation factor 1-gamma
- Tyrosine--tRNA ligase
- Bifunctional glutamate/proline--tRNA ligase
- leucine--tRNA ligase
- Valine--tRNA ligase
- Aspartyl-tRNA synthetase, mitochondrial, isoform A
- Probable phenylalanine--tRNA ligase, mitochondrial
- Tryptophan--tRNA ligase, mitochondrial
- isoleucine--tRNA ligase
- Alanine--tRNA ligase, mitochondrial
Sequence:
MQIIGNCSSKLLRHKYLCQPRVYSLYYSTLKDAANELPLAAGYQPQPVENAYWEREHRQANLPKASASSCKRGTYRMLLPPPNVTGNLHLGHALMATVQDVIARQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFLDEVWRWKAEKGAGIVQDLRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWCTALRSAISDIEVDSVEITEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRPETILGDVAVAVHPLDPRYAKYRNIDQVKLKHPFRDDTIPLVFDITVDQEFGTGAVKITPAHDKFDFELATRHKLEPRQVFTETGLVVDAYSEYKGIPRFEARDLIVNRLEEMDLLRQVRSHTMQLPICSRSKDVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWLQDSRDWCISRQLWWGHQVPAYEVIDSQGNSQWVAALDEKTARQKAMRLIGSEEFTLKRDPDVLDTWFSSSLLPFSTAGWPEESYKERYPLDIMQTGHDIIFFWVARMMMLGLKLTGEAPFQRILLNGIVCDAHGRKMSKSIGNIVAPQQVVQGASLESLKAGLEQSCEAGIITPSELKASTIGMTQMFPNGIQECGTDALRFTLMSHNIKSHFISFDVNACHTNKLFLNKVWQAMRFTLGSAKGLGISLHQFETLEGVNLGLWDRWIVGRLAETLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTKPAIGNRSADAYIHVGTLTACLSWGLQAMAPYAPFVASELLQHVPLNIELKLSDYKDEKLEEEVNEIVNICHNVRQVKSRNEISKRHHPQLSLFAQNTDSEGVLRRHLPQIKVLSRCEDVELELFDESSKISKQLSYFSTAGALCSFGLKLSDGLDLTPEKRDEMQKANAKKLKKLVTELQRYRMRLDNEAFQLMADKKVKSHFENKVKELEAEINSLTRLAVLS
Protein: Probable inactive receptor kinase RLK902 (Receptor-like kinase 902) (Q9LVI6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:15388970, ECO:0000269|PubMed:17397506}; Single-pass membrane protein {ECO:0000269|PubMed:15388970, ECO:0000269|PubMed:17397506}.
Interaction partners:
- Protein ENHANCED DISEASE RESISTANCE 4
- Uncharacterized TPR repeat-containing protein At1g05150
- Rhomboid-like protein 14, mitochondrial
- Probable LRR receptor-like serine/threonine-protein kinase IRK
Sequence:
MRLFFTPSMSNLSIFFSILLLSLPLPSIGDLAADKSALLSFRSAVGGRTLLWDVKQTSPCNWTGVLCDGGRVTALRLPGETLSGHIPEGIFGNLTQLRTLSLRLNGLTGSLPLDLGSCSDLRRLYLQGNRFSGEIPEVLFSLSNLVRLNLAENEFSGEISSGFKNLTRLKTLYLENNKLSGSLLDLDLSLDQFNVSNNLLNGSIPKSLQKFDSDSFVGTSLCGKPLVVCSNEGTVPSQPISVGNIPGTVEGSEEKKKRKKLSGGAIAGIVIGCVVGLSLIVMILMVLFRKKGNERTRAIDLATIKHHEVEIPGEKAAVEAPENRSYVNEYSPSAVKAVEVNSSGMKKLVFFGNATKVFDLEDLLRASAEVLGKGTFGTAYKAVLDAVTLVAVKRLKDVTMADREFKEKIEVVGAMDHENLVPLRAYYYSGDEKLLVYDFMPMGSLSALLHGNKGAGRPPLNWEVRSGIALGAARGLDYLHSQDPLSSHGNVKSSNILLTNSHDARVSDFGLAQLVSASSTTPNRATGYRAPEVTDPRRVSQKADVYSFGVVLLELLTGKAPSNSVMNEEGMDLARWVHSVAREEWRNEVFDSELMSIETVVSVEEEMAEMLQLGIDCTEQHPDKRPVMVEVVRRIQELRQSGADRVG
Protein: N-acetyltransferase Eis (EC 2.3.1.-) (Aminoglycoside N-acetyltransferase) (Enhanced intracellular survival protein) (Protein-lysine N-acetyltransferase) (P9WFK7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Effector that is released into the host cell and affects host immune responses; it negatively modulates inflammation, macrophage autophagy, and cell death through redox-dependent signaling. Acts as an acetyltransferase. Acetylates 'Lys-55' of dual-specificity protein phosphatase 16 (DUSP16)/mitogen-activated protein kinase phosphatase-7 (MKP-7), a JNK-specific phosphatase; this leads to the inhibition of JNK-dependent autophagy, phagosome maturation, and ROS (reactive oxygen species) generation for enhanced intracellular survival of M.tuberculosis. Inhibits Con A-mediated T-cell proliferation in vitro. Treatment of T-cells with Eis inhibits ERK1/2, JAK pathway, and subsequent production of tumor necrosis factor-alpha (TNF-alpha) and interleukin-4 (IL-4); on the contrary, there is increased production of interferon-gamma (IFN-gamma) and interleukin-10 (IL-10), which indicates that immunity in response to Eis treatment is skewed away from a protective T(H)1 response and Eis disturbs the cross regulation of T-cells. When expressed in M.smegmatis, enhances intracellular survival of the bacteria in host macrophages during infection.
Subcellular location: Secreted {ECO:0000269|PubMed:11401966}. Host cytoplasmic vesicle, host phagosome {ECO:0000269|PubMed:17259625}. Extracellular vesicle, bacterial extracellular vesicle {ECO:0000269|PubMed:17259625}. Host extracellular space {ECO:0000269|PubMed:17259625}. Note=Eis is present in the macrophage cytoplasm from 4 to 96 hours post-infection. {ECO:0000269|PubMed:17259625}.
Interaction partners:
- 16S/23S rRNA
- Probable arabinosyltransferase B
- Probable transcriptional regulator WhiB7
- Nicotinamidase/pyrazinamidase
- Enoyl-[acyl-carrier-protein] reductase
- Multidrug efflux pump Tap
- Catalase-peroxidase
- DNA-directed RNA polymerase subunit beta
- Small ribosomal subunit protein uS12
- DNA gyrase subunit A
Sequence:
MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
Protein: Glutathione S-transferase 3 (EC 2.5.1.18) (GST class-phi member 3) (GST-III) (P04907)
Organism: Zea mays (Maize)
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the detoxification of certain herbicides.
Interaction partners:
- methionine--tRNA ligase
- methionine--tRNA ligase
- methionine--tRNA ligase
Sequence:
MAPLKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGDEVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFHPNASPLVFQLLVRPLLGGAPDAAVVEKHAEQLAKVLDVYEAHLARNKYLAGDEFTLADANHALLPALTSARPPRPGCVAARPHVKAWWEAIAARPAFQKTVAAIPLPPPPSSSA
Protein: Protein FixA (P60566)
Organism: Escherichia coli (strain K12)
Function: Required for anaerobic carnitine reduction. May bring reductant to CaiA.
Interaction partners:
- Protein FixB
- Ferredoxin-like protein FixX
- Protein FixC
- Putative electron transfer flavoprotein subunit YdiR
- Crotonobetainyl-CoA reductase
- Putative electron transfer flavoprotein subunit YgcQ
- Probable acyl-CoA dehydrogenase YdiO
- Putative metabolite transport protein YaaU
- Probable electron transfer flavoprotein-quinone oxidoreductase YdiS
- Ferredoxin-like protein YdiT
Sequence:
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
Protein: G-protein-signaling modulator 2 (Mosaic protein LGN) (P81274)
Organism: Homo sapiens (Human)
Function: Plays an important role in mitotic spindle pole organization via its interaction with NUMA1. Required for cortical dynein-dynactin complex recruitment during metaphase. Plays a role in metaphase spindle orientation. Also plays an important role in asymmetric cell divisions. Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11781568, ECO:0000269|PubMed:15632202, ECO:0000269|PubMed:22074847}. Cytoplasm, cell cortex {ECO:0000269|PubMed:15632202, ECO:0000269|PubMed:21816348, ECO:0000269|PubMed:22074847, ECO:0000269|PubMed:22327364}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:11781568, ECO:0000269|PubMed:21816348}. Lateral cell membrane {ECO:0000269|PubMed:26766442}. Note=Localizes in the cytoplasm during interphase and at cell cortex during metaphase (PubMed:11781568, PubMed:15632202, PubMed:22074847). Colocalizes with NUMA1 to mitotic spindle poles (PubMed:11781568, PubMed:21816348). Localized at the central and lateral cell cortex regions in a RanGTP-dependent manner (PubMed:22327364). In horizontally retinal progenitor dividing cells, localized to the lateral cortical region. In vertically retinal progenitor dividing cells, localized at the polar cortical region (By similarity). {ECO:0000250|UniProtKB:Q8VDU0, ECO:0000269|PubMed:11781568, ECO:0000269|PubMed:15632202, ECO:0000269|PubMed:21816348, ECO:0000269|PubMed:22074847, ECO:0000269|PubMed:22327364}.
Interaction partners:
- Nuclear mitotic apparatus protein 1
- Protein inscuteable homolog
- Guanine nucleotide-binding protein G
- Whirlin
- Guanine nucleotide-binding protein G
- Partitioning defective 3 homolog B
- FERM and PDZ domain-containing protein 4
- Guanine nucleotide-binding protein G
- Disks large homolog 3
- FERM and PDZ domain-containing protein 1
Sequence:
MEENLISMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDASNSIDHRIPNSQRKISADTIGDEGFFDLLSRFQSNRMDDQRCCLQEKNCHTASTTTSSTPPKMMLKTSSVPVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNSQSVLSHLMTNDNKEADEDFFDILVKCQGSRLDDQRCAPPPATTKGPTVPDEDFFSLILRSQGKRMDEQRVLLQRDQNRDTDFGLKDFLQNNALLEFKNSGKKSADH
Protein: Dynein light chain (A0A178WMH3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|RuleBase:RU365010}.
Interaction partners:
Sequence:
MEGVELELERRSKFLNSLIQKKKAKEQQDQKDEFNVRVRASDMPLPQQNRAFSLSREILNATPGKADNKRLAHALKKDFDSAYGPAWHCIVGTSFGSYVTHSTGGFLYFQIDKVYVLLFKTAVEPLDQK
Protein: Association with the SNF1 complex (ASC) domain-containing protein (Q9NAH7)
Organism: Caenorhabditis elegans
Interaction partners:
- CBS domain-containing protein
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
- CBS domain-containing protein
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- CBS domain-containing protein
- CBS domain-containing protein
- Serine/threonine-protein kinase par-4
- Forkhead box protein O
- CBS domain-containing protein
- Target of rapamycin homolog
Sequence:
MGNNQSGGPDARYGGPNDKAGLRRHRMMSETAKIAGQVLPNPDGGPPMIFDDGNEDKSGECPVVFRWSFTQNAQPRVVHIVGSWDNWQTRIPMVKSTNDFSTIIDLQPGQYEYKFQVDGSWVVDDNQGKAQDVHGNENNMINIQDSDFAVFEALDEDFQSSTAGEVLRGESESTKNHDTPNDRELEKLRSFTQEIPSMDMLRKAAGPPVIPPQLMQVLLNKETPESCDPNVLPEPNHVMLNHMYALSIKDSVMVLSSTQRYRKKFVTTLLYKPV
Protein: Inner membrane complex protein 1e, putative (O97229)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Gametocyte-specific protein
Sequence:
MVKCNDSNQSKNCTRNFCNVNEEDRKEEGMMSQKDNENMYNPNDIHNNNYNNYYTNNYSVEKNKFSQNSMNQENYENFVDCPPQNARILKPLIQEKIVEIMKPEIEEKIIEVPQVQYIEKLVEVPHVILQEKLIHIPKPVIHERIKKCSKTIFQEKIVEVPQIKVVDKIVEVPQYVYQEKIIEVPKIMVQERIIPVPKKIVKEKIVEIPQIELKNIDIEKVQEIPEYIPEVVQKDIPYTQIVDRPYHVEKIVEVPHVQHIYRNIVSPQYRHIPKPVEIPMAHYRTFPVEKIVDRNVPVPVELQIVQEFLCPKIEARYKEIPVPVHVQRIIEHPIPKDAMNNPHLLPLYYQEDNNIEMSTNKKNTMEQNKNKNCFIFNLNRNDSRNSSHASPSVELLLHNDKSQKQFYNNHTNKKTSIISNPNVFNNYNQNGTLNQFNPNDNINNNMEHIIHHNNNNIPSNVNFKSFHDNVITHNKINNNMPYENNTVLKNNYSVNIPQTYTTKEFANNIYSSPSPVLSSSHTEHA
Protein: Bifunctional diacylglycerol diphosphate phosphatase/phosphatidate phosphatase (Q5AH74)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Phosphatidate phosphatase
- Phospholipid:diacylglycerol acyltransferase
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- Lysophospholipid acyltransferase
- Phosphatidate phosphatase
- Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
- Phospholipase
- Diacylglycerol kinase
- Patatin-like phospholipase domain-containing protein
- Phosphatidate cytidylyltransferase
Sequence:
MALYDIINYFYGSNSKFNRITWGFKSPTFIKWRITDFILIIVLIVLFFVTSQAEPFHRQFYLNDMTIQHPFAEHERVTNIQLGLYSTVIPLSVIIIVALISTCPPKYKLYNTWVSSIGLLLSVLITSFVTNIVKNWFGRLRPDFLDRCQPANDTPKDKLVSIEVCTTDNLDRLADGFRTTPSGHSSISFAGLFYLTLFLLGQSQANNGKTSSWRTMISFIPWLMACYIALSRTQDYRHHFIDVFVGSCLGLIIAIWQYFRLFPWFGGNQANDSFNNRIMIEEIKRKEEIKQDENNYRRISDISTNV
Protein: Lipoate-protein ligase B (EC 6.3.1.20) (Q8IB70)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Glycine cleavage system H protein
- Lipoyl synthase, apicoplast
- Acyl carrier protein, mitochondrial, putative
- Inactive lipoate--protein ligase 2
- Lipoate--protein ligase 1
Sequence:
MNKINLLVLISLTFIILLNPKMKVGKLKKRKNSGLLYPYFKNKSFRLNRYIFIKPIKSVKLNYKKKKMNLTHEICILNCSEKLIDYKLAFQLQNILHHSKIIMKNKNEVQISNHLELKKFKNFKENMEKYDFCFILQHTPCYTLGSVANCSDILLDKENYYIEELGDIYNNLYSNEIIHLMNKCETIQDKINQSDIYNENTNYFNNFLKHCRQRKIPIYRVNRGGKATYHGPGQLVLYFIFNLKNYPSNYNERIINKHYKYTNKENFPSKTSEYEKNNIYTNSNSKENISSIERTFDLRTTINNFQKIGMETLQKFNIKTHCKKDTIGIFYKDKKIISIGLKITKYISMHGLSLNFNLDNNFLKYLLSCGMNHNDYISMHEINEMKKKNYIYQKGKIASSSNILNELTLNITESLKKVFNVKVRNIKDIREMFY
Protein: Isoflavone 7-O-methyltransferase (EC 2.1.1.150) (Daidzein 7-O-methyltransferase) (Q84KK5)
Organism: Glycyrrhiza echinata (Licorice)
Function: 7-O-methyltransferase involved in the biosynthesis of isoformononetin. Can use daidzein as substrate, but not medicarpin or 2,7,4'-trihydroxyisoflavanone.
Interaction partners:
Sequence:
MASSINGRKPSEIFQGQALLYRHIYAFIDSMCLKWIVELDIPNIIHNHGKPITVSELVSILKVPQTKAGNVQRIMRYMAHNGFFERVRIQEEQEENEAYALTAASELLVKGSELCLAPMVECVLDPTLSGSYHQLKKWIYEEDLTLFGVSLGSHFWEFLNENPEYNKSFNDAMASDSQMINLALRDCNSGFEGVESIVDVGGGIGTTAKIICDTFPNLKCIVFDRPKVVENLSGTNNLSYVGGDMFQSVPKADAVLLKWILHNWTDNDCRRILEKCKEAVSSDGEKGKVIIIEMVINENQDEHEITGTKLLMDVNMACLNGKERSEEEWKKLFIEAGFRDYKISPLTGFLSLIEVYP
Protein: Paraneoplastic antigen Ma1 homolog (Q8VHZ4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- RNA helicase
- Zic family member 4
Sequence:
MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEETLQAAMPQVSYRVLGRMFWREENAKAALLELTGTVDYSLIPREMPGKGGLWKVVFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPAPAPGPEMPAEMLNYILDNVIQPLVESIWYKKLTLFSGRDIPGPGEETFDSWLEHSNEVIEEWQVSDIEKRRRLMESLRGPAADVIRILKTNNPAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIRLEPLLQKVVDKGAIDKDNVNQARLEQVIAGANHSGALRRQLWLTGATEGPAPNLFQLLVQIREEEAKEEEEEAEAALLQLGLEGHF
Protein: Uncharacterized protein (D6XK81)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGQKPSITTLLRQCIYNQDTDGFRALIGEHENELIPGCLEDNIFVEVITKKCEPEIVDTVVKLANENQLASLVATAVLYDHSLPLGPLFGMMKERERTIEEHQLKYLFLTLCERGRTEAVRVFVENKCYDPSDPRPLRAVVRGQLKNPNVDTDLLMLVLSSHAPQPDDVKCLIETYLAEAENGDVRKVVEKCLVGFHQ
Protein: Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) (Q86X52)
Organism: Homo sapiens (Human)
Function: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000305|PubMed:11514575}; Single-pass type II membrane protein {ECO:0000305|PubMed:11514575}. Secreted {ECO:0000269|PubMed:21129727}.
Interaction partners:
- Chondroitin sulfate synthase 2
- Chondroitin sulfate synthase 3
- Chondroitin sulfate N-acetylgalactosaminyltransferase 2
- Chondroitin sulfate N-acetylgalactosaminyltransferase 1
- Beta-1,4 N-acetylgalactosaminyltransferase 1
- Chondroitin sulfate glucuronyltransferase
- Beta-1,4-galactosyltransferase 2
- Decorin
Sequence:
MAARGRRAWLSVLLGLVLGFVLASRLVLPRASELKRAGPRRRASPEGCRSGQAAASQAGGARGDARGAQLWPPGSDPDGGPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVQFFSSEGSDTSVPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLENFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHNSKIHQAITLHPNKNPPYQYRLHSYMLSRKISELRHRTIQLHREIVLMSKYSNTEIHKEDLQLGIPPSFMRFQPRQREEILEWEFLTGKYLYSAVDGQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEELDAQELAKRINQESGSLSFLSNSLKKLVPFQLPGSKSEHKEPKDKKINILIPLSGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRDYRIKYPKADMQILPVSGEFSRALALEVGSSQFNNESLLFFCDVDLVFTTEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTYGSTQQLAEMWLEKNDPSYSKSSNNNGSVRTA
Protein: PHD finger protein 8 (H0Y3N9)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASVPVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNCEVLHGPSIMKKRRGSSKGHDTHKGKPVKTGSPTFVRELRSRTFDSSDEVILKPTGNQLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVTRQADCKMKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFERPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVDKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFRFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDEIPETVRTVQLIKDLAREIRLVEDIFQQNVGKTSNIFGLQRIFPAGSIPLTRPAHSTSVSMSRLSLPSKNGSKKKGLKPKELFKKAERKGKESSALGPAGQLSYNLMDTYSHQALKTGSFQKAKFNITGACLNDSDDDSPDLDLDGNESPLALLMSNGSTKRVKSLSKSRRTKIAKKVDKARLMAEQVMEDEFDLDSDDELQIDERLGKEKATLIIRPKFPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEGKLGNGSGAGGILDLLKASRQVGGPDYAALTEAPASPSTQEAIQGMLCMANLQSSSSSPATSSLQAWWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENASLDEQDSLGACFKDAEYIYPSLESDDDDPALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDSNLSLTVPAPTVAATPQLVTSSSPLPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSNQAGQGKRPKKGLATAKQRLGRILKIHRNGKLLLRQVIVQAECRQAIHEPKLKRRDAHP
Protein: Probable RNA-binding protein 46 (RNA-binding motif protein 46) (P86049)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:36001654, ECO:0000269|PubMed:36129965, ECO:0000269|PubMed:36726756}.
Interaction partners:
- Lateral signaling target protein 2 homolog
Sequence:
MNEENTDGTNGCSKVRTGTQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFSKFKPGAVERVKKLRDYAFVHFFHREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQISPNSENLLVYANKEESHSKSLGKPPTLPTRLNGQHSPSPPEIERCTYPFFPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDFNFRRSSINSLSPVSTTLSSGTPSMLPYTSRPSSYPSYPLSPTISLANGSHVGQRLYISNQASFF
Protein: Uncharacterized protein (A0A060XT52)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Troponin I, slow skeletal muscle
- Troponin I type 1a
- Troponin I, fast skeletal muscle
- Troponin I, fast skeletal muscle
- Troponin I, fast skeletal muscle
- Troponin T type 3a
- Troponin I, skeletal, slow c
- Troponin I4a
- Troponin I, slow skeletal muscle
- Troponin I, slow skeletal muscle
Sequence:
MPESFFLPENYSSAVFADVCISNPITCTSHRPQFKAPKIPDGEKVDFDDIQKKRQNKDLVELQALIDAHFEHRKKEEEELIALKERIEKRRAERAEQNRIRSEKEKERAARREEERLKREEADAKKKADEDAKKKSALSSMGSNYSSHLQKADSKRGGKKETEREKKKKILAGRRKVLNIDHLNEEKLKEKAKELHEWMKTLESEKFDNMERLKRQKYEVTTLRKRVEELSKFSKKGKTVRRK