wanglab/gogpt-training-data huggingface dataset:
Protein: Nitric oxide synthase (EC 1.14.13.39) (Q800V0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004468}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004468}. Cell projection, dendritic spine {ECO:0000256|ARBA:ARBA00004552}.
Interaction partners:
Sequence:
MQESEPSVCQLQPNIISVRLFKRKIGGLGFLVKQRVCKPPVIVSDLIRGGAAEECGLVQVGDIVLAVNNKPLVDMSYERALETLKNVSPESHAVLILRGPEGFTTHLETTLSSDGKTKTIRVTRPVNPAQSRPCERCSPLTPNMTKELRAIENLSSSSTPRKESRDDKPLIPLLSQDSLLREGGHAGLLLNGVEDNNDLLKEIEPVLKLIKNSKKEINGEGQRVIDRKDAEVQVERDLGVGNGQNAQLASDNDRVFDDLWRKDNMPTVLNNPYSESDKPQSYERVSPTKAVQNGSPSKCPRFMKVKNWETGALYNDTLHHSSSKVPICTEHVCIGSIMVPNQHAHEPDEDRRKEELLPLATDFIDQYYTSIKRCCSKAHVDRLEEVKKEIETSGTYQLKDTELIYGAKHAWRNAARCVGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQKTDGKHDFRVWNSQLIRYAGYKQPDGSILGDPASVELTEICMQQGWKAPKGRFDVLPLLLQANGNDPELFEIPDDLVLEVPIIHPKFEWFKELNLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDFCDSSRYNILEEVATMMGLDTRKTSSLWKDQALVEINIAVLYSYQMSKVTIVDHHSATESFMKHMENEYRVRGGCPGDWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGVNGTPTKKRAIGFKKLAKAVKFSATLMGQAMAKRVKATILFATETGKSQDYAKTLCEIFKHAFDAKVMSMDEYDTVDLEHETLVIVVTSTFGNGDPPENGEKFGAALMEMRHPTTSVEDRKTYKVRFNSVSSYSDTRKSSSDEPESKANFESTGPLANVRFSVFGLGSRAYPHFCAFAHAVDTLFEELGRERILRMGEGDELCGQEESFRTWAKKVFKAACDVFCVGDDVNIEKANDSLISNDRSWKKSKFRMTYTAEAPTLTQALYSIHKKKVYGAKVVQRQNLQSARSNRLTIFVRLDANNHESLKYLPGDHLGVFPGNNEDLVTTLIEKLEDAPPVNQIVKVEFLEERNTALGVISNWTDESRIPPCTIYQAFKYFLDITTPPSPVLLQQFAPLATNEKQRKRLEVLSKGLQEYEEWKWYNNPTMVEVLEEFPSLQIPSTLLLTQLPLLQPRYYSISSSPDLYPGEIHLTVAVVSYRPRDGEGPIHHGVCSSWLNSLDEGDTVPCFVRGAPSFRMPKDSQVPCILIGPGTGIAPFRAFWQQRQYDVENKGIKACPMILVFGCRQSQIDHIYKEQTIQAKNKEVFKELYTAYSREPGRPKKYVQDVLREQLSETVYKCLREEGGHIYVCGDVTMAGDVLKTVQQIFKLHGNMSLEDAGFYISKLRDENRYHEDIFGVTLRTCEVTNRLRSESIAYIEESKKDIDEVFCS
Protein: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit (EC 2.4.1.-) (Glycosyltransferase GtfA) (O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase) (A0A0H2URG7)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Required for the polymorphic O-glycosylation of serine-rich repeat protein PsrP. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in PsrP. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins encoded upstream in the same operon (Probable). The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to PsrP (experimentally characterized with truncated PsrP-SSR1 constructs); this subunit alone has weak N-acetylglucosaminyl transferase activity that is 10-fold stimulated by GtfB. The complex requires at least a 25 residue-long peptide for activity; the in vitro assay has only been seen to glycosylate Ser residues. The alpha linkage was shown in L.reuteri.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01472}. Cell membrane {ECO:0000250|UniProtKB:A1C3L9, ECO:0000255|HAMAP-Rule:MF_01472}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01472}. Note=Cell membrane association requires GtfB. {ECO:0000250|UniProtKB:A1C3L9, ECO:0000255|HAMAP-Rule:MF_01472}.
Interaction partners:
Sequence:
MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMILADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVLRVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAVLYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVILDRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFIVSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKHIDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYSQYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVEDQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD
Protein: ER-localized J domain-containing protein 5 (P43613)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: DnaJ-like chaperone required for the folding capacity of the endoplasmic reticulum.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17157937}; Single-pass type I membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17157937}.
Interaction partners:
- DnaJ-related protein SCJ1
- Protein translocation protein SEC63
- J domain-containing protein 1
- DnaJ-like chaperone JEM1
- SAGA complex subunit SGF29
- Protein HLJ1
- Mitochondrial DnaJ homolog 2
- DnaJ protein homolog XDJ1
- Auxilin-like clathrin uncoating factor SWA2
- Pre-mRNA-splicing factor CWC23
Sequence:
MNGYWKPALVVLGLVSLSYAFTTIETEIFQLQNEISTKYGPDMNFYKFLKLPKLQNSSTKEITKNLRKLSKKYHPDKNPKYRKLYERLNLATQILSNSSNRKIYDYYLQNGFPNYDFHKGGFYFSRMKPKTWFLLAFIWIVVNIGQYIISIIQYRSQRSRIENFISQCKQQDDTNGLGVKQLTFKQHEKDEGKSLVVRFSDVYVVEPDGSETLISPDTLDKPSVKNCLFWRIPASVWNMTFGKSVGSAGKEEIITDSKKYDGNQTKKGNKVKKGSAKKGQKKMELPNGKVIYSRK
Protein: Protein ENHANCED PSEUDOMONAS SUSCEPTIBILITY 1 (EC 2.3.1.-) (Q9FH97)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for pathogen-induced salicylic acid (SA) accumulation and SA-mediated resistance to virulent and avirulent pathogens (e.g. P.syringae).
Interaction partners:
- 4-substituted benzoates-glutamate ligase GH3.12
- Isochorismate synthase 1, chloroplastic
- Isochorismate synthase 2, chloroplastic
Sequence:
MEEELVVISKSIVNPRSLKKPTSVKKIQLTPWDLSRLRFGYLQRGLLFHKIEVKQLQASLSVALDRFYPLAGRLVKLKNDDDTVSFFISCDGSGVEFVHAVAKNIELSDVLELSGSVPGFFASFFPATGIKNYHGVSRSLLMVQVTEMKDGVFIGFGYNSTVADATSIWKFINAWSEICSKDSSGSQTFQRRLHLKGWFFDEIDYPIHIPDPETKPTSYVTTPTNLQEKMFHVTKENVLKLDAKANDEADQKISSIQAVLAYIWRSMVKHSGMSREEETHCRLPINMRQRLNPPLEEECFGNVSQTGIATVTVGELLDHGLGWAAMQINNMELSQTDEKAKAFAENWVKNIKIPVSVGSKDLVVTNSHRFDVYCNDFGWGKPIAARAGPPYLNGRLVVFKGIGEASLDFQACLLPQVVEKLVKDAEFNEYVSIV
Protein: Transcription factor MYB1 (Myb-related protein 1) (AtMYB1) (Q42575)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
- Transcription factor bHLH3
- Dihydroflavonol 4-reductase
- Transcription factor SRM1
- Naringenin,2-oxoglutarate 3-dioxygenase
- Flavonoid 3'-monooxygenase
Sequence:
MEAEIVRRSEVTGLRREVEESSIGRGDCDGDGGDVGEDAAGFVGTSGRGRRDRVKGPWSKEEDDVLSELVKRLGARNWSFIARSIPGRSGKSCRLRWCNQLNPNLIRNSFTEVEDQAIIAAHAIHGNKWAVIAKLLPGRTDNAIKNHWNSALRRRFIDFEKAKNIGTGSLVVDDSGFDRTTTVASSEETLSSGGGCHVTTPIVSPEGKEATTSMEMSEEQCVEKTNGEGISRQDDKDPPTLFRPVPRLSSFNACNHMEGSPSPHIQDQNQLQSSKQDAAMLRLLEGAYSERFVPQTCGGGCCSNNPDGSFQQESLLGPEFVDYLDSPTFPSSELAAIATEIGSLAWLRSGLESSSVRVMEDAVGRLRPQGSRGHRDHYLVSEQGTNITNVLST
Protein: PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor) (Q15004)
Organism: Homo sapiens (Human)
Function: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
Subcellular location: Nucleus {ECO:0000269|PubMed:11313979, ECO:0000269|PubMed:16288740, ECO:0000269|PubMed:21673012, ECO:0000269|PubMed:23000965}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:21673012}. Note=Following DNA damage, localizes to DNA damage sites (PubMed:21628590). Colocalizes with centrosomes in perinuclear region (PubMed:21673012).
Interaction partners:
- Proliferating cell nuclear antigen
- Ubiquitin-conjugating enzyme E2 C
- Baculoviral IAP repeat-containing protein 5
- DNA topoisomerase 2-alpha
- Inhibitor of growth protein 1
- Nucleolar and spindle-associated protein 1
- Outer kinetochore KNL1 complex subunit ZWINT
- Abnormal spindle-like microcephaly-associated protein
- Ribonucleoside-diphosphate reductase subunit M2
- Centromere protein F
Sequence:
MVRTKADSVPGTYRKVVAARAPRKVLGSSTSATNSTSVSSRKAENKYAGGNPVCVRPTPKWQKGIGEFFRLSPKDSEKENQIPEEAGSSGLGKAKRKACPLQPDHTNDEKE
Protein: 26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Multiubiquitin chain-binding protein) (O35226)
Organism: Mus musculus (Mouse)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome regulatory subunit 6A
- 26S proteasome non-ATPase regulatory subunit 2
- Proteasome subunit alpha type-1
- 26S proteasome regulatory subunit 4
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 1
Sequence:
MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATPGTEDSDDALLKMTINQQEFGRPGLPDLSSMTEEEQIAYAMQMSLQGTEFSQESADMDASSAMDTSDPVKEEDDYDVMQDPEFLQSVLENLPGVDPNNAAIRSVMGALASQATKDGKNDKKEEEKK
Protein: Transforming growth factor beta (E9QHW0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- TGF-beta receptor type-2
- Receptor protein serine/threonine kinase
- Serine/threonine-protein kinase receptor
- Decorin
- TGF-beta receptor type-2
- Fibromodulin a.
- Fibromodulin b.
- Transforming growth factor beta
- Left-right determination factor
- Left-right determination factor.
Sequence:
MKAESLLLALQCLLGFVQYSRALSTCNPLDLELIKRKRIEAIRGQILSKLRLPKEPEVEEKELIENIPAELISVYNSTMELNEEQAANPVQHTIEDPTEEEYYAKEIHKFTMMEEKPEKYLVFNITDIKHKLGANHVLYQAEFRLRIKEPKMGDSEQRLELYQVTGNKSRYLNSRFISLQTAGKWVSFDVTSTLKDWLQMPEEKQEFQLQLACSCKPESQNTEFLFKIAGLSRNRGDTGLLADQVAKPYILVMSHPADGHSPAKSRRKRETDAVCTEKSEGCCVRSLYIDFRKDLGWKWIHEPSGYYANYCTGSCSYVWTSENKYSQVLALYRHHNPGASAQPCCVPQVLDPLPIIYYVGRQHKVEQLSNMIVKTCKCC
Protein: Cone-rod homeobox (Crx protein) (Q8JIZ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Nuclear receptor subfamily 2, group E, member 3.
- Leucine zipper transcription factor.
- Neurogenic differentiation factor 1
- Rhodopsin
- Green-sensitive opsin-4
- Green-sensitive opsin-2
- Green-sensitive opsin-1
- Green-sensitive opsin-3
- Rhodopsin
- Rhodopsin.
Sequence:
MMSYIKQPHYAVNGLTLSASGMDLLHTAVGYPATPRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQTSGQPKPRPPKKKSSPPPDLTSDPGTSSSVVAAPTPTVPPSVSAGTAPVSVWSPTSLSPLPDPLCGSGTPCVQRPAPYPMSYGQPSSYSQGYGSSPYFSGLDCSPYLSPMTTQLSASGGALSPLTVPSMGGSLSQSPSLSSQGYSTASLGFSSVDCLDYKDQQAWKLNFSTVDCLDHKFQVL
Protein: Zinc finger protein 69 (Zinc finger protein 642) (A2A761)
Organism: Mus musculus (Mouse)
Function: Putative transcription factor that appears to regulate lipid metabolism.
Subcellular location: Nucleus {ECO:0000269|PubMed:26232096}.
Interaction partners:
- Palmitoyltransferase ZDHHC23
- VPS10 domain-containing receptor SorCS1
- TBC1 domain family member 1
Sequence:
MPQQLLITPATEATWVKLKEVSLWEDVTKMFGGEALLSHDANGTQQESLADGTTPGTPAAGSHDGATPGTTATGSHDEATPGTPAAGSHDGETPGIPAAGSHDGETPGTPTAGSHDGVTPGTTAAGSQESLTFKDIAVDLSQEEWGQLAPAYQDLYREVMLENYRNLVSVAGYQLSKPTVISQLEKGEGPCMAESQGPEDPILDVKNKLETKESTAEDDISVKLDHGITRGRLIEDDIVCSPLKKASSYSDTLESHRATCGKGTRRAIWTHKKKRQEGNKLENPESSNVILEQKHRKHKPARKRNKYKLDSIDHPVSCMRARRYPCNVCEKMFKQPIHLVEHMRTHTGEKPFRCKECGRAFSQSASLNTHQRIHTGEKPFACEECGKAFRHRSSLNQHHRTHTGEKPFTCDKCQKAFSQNISLVQHLRTHSGEKPFSCSECGKPFRQIRHLSEHVRIHTGEKPYKCTSCCKTFSHRAYLTHHQRIHTGERPYKCKECGKAFRQRIHLSNHRTVHTGVKAYECNRCGKAYRHDSSFKKHQRHHTGEKPYECTECGKSFSYNSSLSRHQKIHRRNTFRDDPGHENKRQL
Protein: Leucine-rich repeat, isoform D (RE71830p) (Q6NND6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTDSIAVDDGGVDECCDSITELPSASFQLQHLVKGRPKRAKTRAPTRPLVTTECAGGSREIGEGLEHFFRPGSVTPTTLTPLVSPTSEECSSLSFVDSPTMSRDGNGHMTSEETTPILEERRPIKLERQSPLLKSASWATRSRSTDNLEKYSPLVGRKSPLVKMRTEGGPGSGSATGAEETSMPSSNLLKATAREDKTRSPSSDSIKSHAAGEGSVIVKTGNGILRTPIVLQKPRPWSVVGSEPKAGGDLITGNGNADSSKTTPDKLEEDDVEIVTFGNTCSGSIVGITPGIALSTSGGGSIVGITPGGALEKKSVRELAAGLNRMELPLKPPVMPRTLLNATSVRTSTSSTGSTSNSVSVSSSTNANTSMTVLNQSQTRSRIVSSTSSTDSTETITERSTTSTSSSSSSSYEKQHAKACANLISNEILSMRNGQLGAKSGSCAESGGVKRIAGKEISTLFEETLVEELQQSMATRRGFRDSTYTKEDVVDL
Protein: Asterless (GH02902p) (Q9VNE4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Serine/threonine-protein kinase PLK4
- Spindle assembly abnormal 4
- Centrosomin
- BcDNA.LD24702
- Pericentrin-like protein, isoform F
- Centrosomal protein 135kDa, isoform B
- Anastral spindle 1, isoform A
- Spindle assembly abnormal protein 6 homolog
- Anastral spindle 2, isoform A
- Centriolar coiled coil protein 110kDa, isoform B
Sequence:
MNTPGISLFQGADALNINSTLDRQEEEEALQDQKRREEELGRIMVNAFDDLLDEENTIDSTTNYQSELEQPPVLPNYPSHPHHKPLQDDAQRANEIEMHRLQILLESKNNELQNVNQVANAAHKKLDDLQKHLSIMQAELDRAIREKQNTHELLVETKETCSNKDSDLDKLRSEKKQLEEDNTRLVGQLEAAKTLLTDVQSKYDMVQASKQKWEERNADLRLKQMEEAHRAQSDLLQQQLCQMKDQLDRKQNELDQINSRYNALQSGHETMLVDKAAKINELSQALDEAQMRCNQLSARPDLQAENRRQQQCIVDLKARIAYLEQTVASLHERLNETTTELDLIDSVIQQHQADESPTSRLSQMGGSRLVGSTPLNPLDRVGHIKQELYRALGNLKNKREEVRRLEKLLEERNQELRVLRDQENQSLVQLETLNEGKMRLENKVKAMQQELEEQKHRSQQESDVHSQLNSIVAERDALREKRQQIEEDLEQLKQQNESLQRNYDQLSQENRQLRTRETADNLRLELERHKILLRDSQSEVERLKKLYSDIATDKESLGYELRKLRESDTLKELQDQRQNLATVQRNLQLAEMKSEELKKLLETEKLSHERDLQALRQRSEREKREEAVAVAKESSENCSKCIESIAEITKAEIQLLKLQNVNSMQAKELKELEHALEQSKNLQAEMQEKIELSNKQDELISDLKERAKQFEAYIRQQEEHKQQNKCTPSPKSNSVSPSDPSPKELTQNRIRLIEQRVRDEMAKLFAAELKRFTNRLQKSEERSQCLQREYQTVCAELQQRQTEVDLLKQTILAERENIDEILAGREEKQKEMLQKCRQELQAKNQRIAELLREVEEQHASIDSERQSMKAVMAQWEKQRQSVDQVEHHWRQQLESLRSTHEEAMRSAQQRYQSAKRTAHNYKLYAEDKEAHMKREYERIKHEYELSLAKIEATMNQHLERRSREKHRDKENVPSNSSSDPITNSNRKPKGNGHS
Protein: Regulator of sigma D (P0AFX4)
Organism: Escherichia coli (strain K12)
Function: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
Interaction partners:
- RNA polymerase sigma factor RpoD
- Phosphocarrier protein HPr
- RNA polymerase sigma factor RpoS
- Anti-sigma-E factor RseA
- ECF RNA polymerase sigma-E factor
- Bifunctional
- Uncharacterized protein YtfK
- Inner membrane protein YohC
- GTP pyrophosphokinase
- NAD-capped RNA hydrolase NudC
Sequence:
MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA
Protein: Verprolin (Q9NET8)
Organism: Caenorhabditis elegans
Interaction partners:
- Serpentine receptor class gamma-2
- Transmembrane protein
- Stress-associated endoplasmic reticulum protein
- RING-type domain-containing protein
- Uncharacterized protein F10E9.1
- Acyl_transf_3 domain-containing protein
- Protein quiver
- Protein TolB
- Tectonic domain-containing protein
- CAP-Gly domain-containing linker protein 1 homolog
Sequence:
MLPKNEKEALVDVDDRIAMLERRLDNAKAARDAFVHHLRGKYPTWKPPLPTMSYQEADFPKLPHYASNHHREPLLSRLSTSDYQWDITNNRNNRSRSMTRLSSKFQPMDIPTSGPLLESDIRRSKIRLREISEELRAMRIDRMSLSTDQWLQEQPFRQHKYLRLNLTENAAEPQIDHLEQARAHLSRINLTETSPIATPTEERKIDISMTENHEKLLAEMRAQAPPTTHVTFQEAPPTQTVVPPVLQEAPPVIAPPTEPVAPPTSTQAPPIAAQAPPTSSVSNLLAQLAGGSDSDDSPRIPAPAATQNLDYSKFLSNLGVGGGMSSDEDDNAFSRPSYQKSRPAVGKSMAAAMMADEDSDVDDFFR
Protein: Myosin-16 (AtMYA3) (AtMYOS3) (Myosin XI J) (AtXIJ) (Q9M2K0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17288617}. Note=Colocalizes with cytoplasmic vesicles and/or organelles.
Interaction partners:
- F-box/kelch-repeat protein At4g05080
- Filament-like plant protein 6
- Protein PLANT CADMIUM RESISTANCE 11
Sequence:
MAENIMVDSHVWVEDPERAWIDGVVLNIKGEEAEIKTNDGRDVIANLSRLYPKDTEAPSEGVEDMTRLSYLHEPAVLDNLATRYELNEIYTYTGNILIAVNPFQGLPHLYDAEVMEKYKEAYFKELNPHVFAIGGIAYREMINEGRNKCILVSGESGSGKTETTKMLMRYLAYFGGHTAVEGRTVENQVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDDVGRISGAAIRTYLLERSRVCQVSDPERNYHCFYLLCAAPPEDVERFKLGDPKSFRYLNQSSCYKLDGVNDAEEYLATRRAMDVVGISEKEQDAIFRVVASILHLGNIEFSKGEDADSSSVKDEQSMFHLQMTSELLMCDPHSLEDALCKRMMVTPEEVIKRSLDPLGAAVSRDGLAKTIYSRLFDWLVNKINISIGQDSHSRRLIGVLDIYGFESFKTNSFEQFCINYTNEKLQQHFNQHVFKMEQGEYQKEEIDWSYVEFVDNKDVVDLIEKKPGGIIALLDEACMLPKSTPETFSEKLYHTFKDHKRFMKPKLTRSDFTLVHYAGDVQYQSDQFLDKNKDYVVAEHQDLLNASKCSFVSGLFPPLPKESSKSKFSSIGARFKLQLQQLMETLNSTEPHYIRCVKPNNLLQPTVFDNANVLHQLRSGGVLEAIRVKCAGYPTNRTFIEFLNRFLILAPEILKGEYEAEVACKWILEKKGLTGYQIGKSKVFLRAGQMAELDAHRTRVLGESARMIQGQVRTRLTRERFVLMRRASVNIQANWRGNIARKISKEMRREEAAIKIQKNLRRQIAKKDYGKTKSSALTLQSGVRTMAARHEFRYKLTTRAATVIQAYWRGYSAISDYKKLKRVSLLCKSNLRGRIARKQLGQSKQADRKEETEKERKVELSNRAEEAVDMSFVLHSEQSDDAESGHGRKAKLSIESEDGLDKSSVLHSEQSDDEELGHERKTKLSIESEDGHSDQSDDEEIEHERKTKHCIQAEDGIEKSYVMHSDQSDDEEIGHKRKTKHSIQAEDGIEKSFVVHSDQSDDEEIGHERKTKHAIQVEDGIQKSFVTCSEKPYNTFSVVSQITSPIRDTEIESLTAEVEMLKALLQVEKQRADISERKCAEARELGERRRKRLEETERRVYQLQDSLNRLLYSMSDQFSQLKSILRSPSMSASTMASAPVVRDDLADSSENSEASSSDSDFTFPAPSPSSDNFSTFNPNQLQVIVQDLSTTEAKGTESYDSDKEGGFEDYF
Protein: Protein peg1 (O42874)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Microtubule binding protein that regulates the stability of dynamic microtubules. Required for mitotic spindle formation.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16951255}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16951255}. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:16951255}. Note=Colocalizes with cytoplasmic microtubules and associates with the mitotic spindle throughout mitosis.
Interaction partners:
- Anaphase spindle elongation protein 1
- Microtubule integrity protein mal3
- Tip elongation protein 1
- Phosphoprotein p93
Sequence:
MADKDAQDFLKFLKSNASTDEKTRCLDTLRSFFNKNNIPNADLGLFVECFRLALTTVNPLLLRSSVACFETFLRRLRAQYPTWLKFRVPMLKNLVIDHIASRDLQKRVLNILIDLWHFNPSEIEKSLIHLSTTSKSAETRIQCFKWFVLAHNAHLSFDVKSLRPALYINLENANPSVREEAKEVLLLIYKNLSTSAKMQFITDVETTSGLRREILQSLVEELSLISSSSEVIIVQNSASSFQPAPFMTAVATLYPGVELENVKPLLANFSKQLEQDSASMLPAFEGRETEQNWSVRQDSVLRLRQYLRGNACIDYLPELLSVLKTLLPGILLALLSLRTTLSSSAIQLIKEMAIILKSNIDPFLELILPNLLKVCSVTKKLASQAANVTFAAILVNCGVLSRNLSFISLAAHDTNAQLRVFSSNWIFMLISLSPELKNLASLQTNLKAFEKLICRGLADSNSQVREVYRKSFWKLSEYFPSVQEELTNTLEPSVLKQLHLANPNRQAASFNFSGPKRAPIRPLSNLRSFSKSQKEETSSNSSNSSGTRRLGLPQRATPASRERVLPYTRSQAFHSTSLPPSLPSGHSPSIAIPSKRSVSATIKDESKTFELLKNIQRKYELILSGSSVDLPSAEFLSSNLTDALYSGSSICYSLIFSHSLLDLTFQYVDIASLLSQFLLCVYDPSNVGHSFALASFPYVKSHYDAHKYFPIVFDVLMNISNMAPHVKVFPFNTNQKRLIIHGCLLWLKEISDTKLNQLENKPFFVTDKLRYYSSKILAMTAKTKLTSKNWIPLSGLLFSLRAHDTFMFDGLLDRLNEESRTKLVSSWSKQDAFDYSKSSTHQEHLSKNLPTLNTSSSSNSSQTDLLVPHGKGETKETEMQSPIESKEGLLSKDTHIESPQGTSLEKENEEEGKNPVESNCSEESLDDHNIDQTLVNKKETLAQDSESLLQKNNALNEKGFENQFGLSSSAAKVLNKDTLDHVSGPISNSVSSSFKDFTRTPFKEINGERETGFELTSYVNALSKKDDINVQKTENVDESVGLNAMFMDNVNQDSLNSVDQSSGKDKLLLTSSTPNKPTTFFMPANEEILGSPAKDYDIHDQSYSVHELHSENMRENVGQSSLIYNNRDYMNTPMNDFSLSFSEIKGGILESPVESPMTGTISPIDADESVLHDIPAYESLNKSESNKYQEQAYSTPLHHTLNVLPKNKWILSRMHKMENGSPINVDKNLDDAVAALEAAVKELNDGSVNTKTLKFCIKVCKETPSMLYHSHGLLPAILHYIESNNSAMHISDCLILLHEFLVQGYQGVDMHTYHNIICILIEKAEKCKDEPVILAGIEDNITLIAEIADLQGLYEFTQQRLQSLNTETGEKSAPLLLMLLSAILMRLKDLEFLETKDLLRHVVLKYIDHTNPEIRKATFNVCLAVNTIVNNVDETFSILGGLNEGQRLLFMHYLKMKSDEKN
Protein: Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3) (TGFR-3) (Betaglycan) (Transforming growth factor beta receptor III) (TGF-beta receptor type III) (P26342)
Organism: Rattus norvegicus (Rat)
Function: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Subcellular location: Cell membrane {ECO:0000305|PubMed:1657406}; Single-pass type I membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:1657406}. Secreted, extracellular space, extracellular matrix {ECO:0000305|PubMed:1657406}. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. {ECO:0000305|PubMed:1657406}.
Interaction partners:
- Transforming growth factor beta-1 proprotein
- Transforming growth factor beta-3 proprotein
- Transforming growth factor beta-2 proprotein
- TGF-beta receptor type-1
- Activin receptor type-2A
- TGF-beta receptor type-2
- Inhibin alpha chain
- Receptor protein serine/threonine kinase
- Bone morphogenetic protein 4
Sequence:
MAVTSHHMIPVMVVLMSACLATAGPEPSTRCELSPINASHPVQALMESFTVLSGCASRGTTGLPREVHVLNLRSTDQGPGQRQREVTLHLNPIASVHTHHKPIVFLLNSPQPLVWHLKTERLAAGVPRLFLVSEGSVVQFPSGNFSLTAETEERNFPQENEHLLRWAQKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLPSQPHEKEVHIIELITPSSNPYSAFQVDIIVDIRPAQEDPEVVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPNSIGFGKESERSMTMTKLVRDDIPSTQENLMKWALDNGYRPVTSYTMAPVANRFHLRLENNEEMRDEEVHTIPPELRILLDPDHPPALDNPLFPGEGSPNGGLPFPFPDIPRRGWKEGEDRIPRPKQPIVPSVQLLPDHREPEEVQGGVDIALSVKCDHEKMVVAVDKDSFQTNGYSGMELTLLDPSCKAKMNGTHFVLESPLNGCGTRHRRSTPDGVVYYNSIVVQAPSPGDSSGWPDGYEDLESGDNGFPGDGDEGETAPLSRAGVVVFNCSLRQLRNPSGFQGQLDGNATFNMELYNTDLFLVPSPGVFSVAENEHVYVEVSVTKADQDLGFAIQTCFLSPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEVDKKRFSFLFKSVFNTSLLFLHCELTLCSRKKGSLKLPRCVTPDDACTSLDATMIWTMMQNKKTFTKPLAVVLQVDYKENVPSTKDSSPIPPPPPQIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETARRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA
Protein: Homeobox protein NANOGP8 (Q6NSW7)
Organism: Homo sapiens (Human)
Function: May act as a transcription regulator (By similarity). When overexpressed, promotes entry of cells into S phase and cell proliferation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:16623708}.
Interaction partners:
- Homeobox protein NANOG
- CD44 antigen
- Signal transducer and activator of transcription 3
- Probable ATP-dependent RNA helicase DDX5
- Ribonuclease 3
Sequence:
MSVDPACPQSLPCFEESDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAENSVAKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGNLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMHFQPNSPASDLEAALEAAGEGLNVIQQTTRYFSTPQTMDLFLNYSMNMQPEDV
Protein: RING/U-box superfamily protein (F4JZ26)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MDGYYSLSPISVLHRIKDSFHFAVSALLANLFSALFTFFFALVGTLLGALTGALIGQETESGFIRGAAVGAISGAVFSIEVFESSLLLWQSDESGIGCLLYLIDVIASLLSGRLVRERIGPAMLSAVQSQVQLPFLFFDASFIILLNFCINNKQMGAVESQFQDHTDIFDTAISKGLTGDSLNRIPKVRITDTSPEIVSCSVCLQDFQVGETVRSLPHCHHMFHLPCIDKWLRRHASCPLCRRHL
Protein: Sulfotransferase (EC 2.8.2.-) (A0EXC5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTESELYSVHKGVFVPTHLHPAESLKYYEDFIFRPDDILIVTYPKSGTIWMQEIVPLVVSEGDLTLVLTVPNWDRVPWLEEHRAILLSLEQRASPRIFATHFHHQMMNPSYFKIEPRVLYVMRNPKDVFISSFHYYGMASFLVNPGTQDEFMEKFLNGNIMFGSWFDHVKGWLNAAEQEHILYISYEEMINDLRASVEKIATFLGKSLSSEVVEKIADHCVFKNMKQNKMSNLSLVPEEFMDQKKSEFLRKGIAGDWKNHFSAAQEERFNAVYDDKMKDVKFKFPWD