wanglab/gogpt-training-data huggingface dataset:
Protein: C-phycocyanin beta subunit (Q54714)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS). Phycocyanin is the major phycobiliprotein in the PBS rod.
Subcellular location: Cellular thylakoid membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Part of the phycobilisome rod. {ECO:0000269|PubMed:31015331}.
Interaction partners:
- Phycobilisome 8.9 kDa linker polypeptide, phycocyanin-associated, rod
- Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 1
- Allophycocyanin alpha chain
- Photosystem I-associated linker protein CpcL
- C-phycocyanin alpha subunit
- Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 2
- Phycobilisome rod-core linker polypeptide CpcG
- Phycobiliprotein ApcE
- Phycocyanobilin lyase subunit alpha
- Phycocyanin alpha phycocyanobilin lyase CpcF
Sequence:
MFDVFTRVVSQADARGEYLSGSQLDALSATVAEGNKRIDSVNRITGNASAIVSNAARALFAEQPQLIQPGGNAYTSRRMAACLRDMEIILRYVTYATFTGDASVLEDRCLNGLRETYVALGVPGASVAAGVQKMKEAALDIVNDPNGITRGDCSAIVAEIAGYFDRAAAAVA
Protein: Centromere protein W (A0A0R4ISL4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Si:ch73-147o17.1
- Centromere protein T
- Centromere protein X
- Centromere protein N
- Centromere protein I
- Centromere protein M
- Centromere protein K.
- Centromere protein P
- Centromere protein H
- Centromere protein O.
Sequence:
MSKKAPRAALKHHMKKNANIRIGKNADLMAQLNLLMVLHRLAEECRVKAFEEKSATIKTHHVRAVAKRNFNTMLEWYFVANESVQKHIPTHLNVPRNS
Protein: Ribosomal RNA small subunit methyltransferase, chloroplastic (EC 2.1.1.-) (Dimethyladenosine transferase 1C) (Protein PALEFACE 1) (O65090)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for methylation of the 3' adenosines in the small subunit of plastid rRNA. Essential for chloroplast biogenesis at low temperatures.
Subcellular location: Plastid, chloroplast {ECO:0000305|PubMed:9596631}.
Interaction partners:
- Bystin
- Periodic tryptophan protein 2
- At3g49990
- Putative U3 small nucleolar ribonucleoprotein
- Transducin family protein / WD-40 repeat family protein
- Probable cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG6
- Putative WD-repeat membrane protein
- At1g42440/F7F22_7
- Protein NUCLEOLAR COMPLEX ASSOCIATED 4
- At3g13230
Sequence:
MMNAVITSATINCNSLSPSWTCGDNSPSKLLLGEISAALSRRRTVKVSCGKSSPDDYHSTLKSLNSRGRFPRKSLGQHYMLNSDINDQLASAADVKEGDFVLEIGPGTGSLTNVLINLGATVLAIEKDPHMVDLVSERFAGSDKFKVLQEDFVKCHIRSHMLSILETRRLSHPDSALAKVVSNLPFNISTDVVKLLLPMGDIFSKVVLLLQDEAALRLVEPALRTSEYRPINILINFYSEPEYNFRVPRENFFPQPKVDAAVVTFKLKHPRDYPDVSSTKNFFSLVNSAFNGKRKMLRKSLQHISSSPDIEKALGVAGLPATSRPEELTLDDFVKLHNVIARE
Protein: Cell cycle regulatory protein (Srw1), putative (AFU_orthologue AFUA_3G08280) (Q5B915)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- 20S cyclosome subunit
- Negative regulator of mitosis
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 5
- Anaphase promoting complex subunit 10
- G2/mitotic-specific cyclin-B
- Tyrosine-protein phosphatase cdcA
- 20S cyclosome subunit
- Protein bimA
Sequence:
MSESNRASSNPAIYGSARALRSTGTHIVSPPGSRTPPSMPAKTTLYFPEPTGVHHTSRSVSGPIDPNALAKALREYEDAGRSRERTPGTSPSRKRQRVYGDRFIPNREGQDLQATYSLLHEDGCPSTPSKTKKRTPHSELHFQKTEEANRMYSRVLRSELFGNTVPQADLDSLPSNTIRSSGINDKTRSHTPPSHVVSALPPASITPSTPHKNLFNYASPRAGSAHPTPSKTPRNQHGPNLNVRSELYSLSPIRYDSQRILETPRKQPRYVNKVPYKVLDAPDLQDDFYLNLVDWGSSNVLGVGLGNSVYMWNSQTGRVTKLCELKDDTVTSVSWIQRGTHLSIGTGKGMVQIWDAERCRRLRTMIGHTNRVGALAWNDHILTSGSRDRHIFHRDVRSPDQYLRRLSGHKQEVCGLRWNTEDGQLASGGNDNKLLVWDKLNETPLYRFSDHTAAVKAITWSPHQHHLLASGGGTADRTIKFWNTATGSLIKEVDTGSQVCNLAWSKNSDEIISTHGYSQNQIVIWKYPRMEQIVSLTGHTFRVLYLAMSPDGQTVVTGAGDETLRFWKIFNRRPGREHGREGSKLAEWGTIR
Protein: Acetyl-CoA acetyltransferase homolog, mitochondrial (3-ketoacyl-CoA thiolase) (EC 2.3.1.-) (Q22100)
Organism: Caenorhabditis elegans
Function: Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16462744}.
Interaction partners:
- Hydroxymethylglutaryl-CoA synthase
- Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial
- Delta
- Probable 3-hydroxyacyl-CoA dehydrogenase B0272.3
- 3-hydroxyacyl-CoA dehydrogenase
- Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1
- Acetyl-CoA carboxylase
- Bifunctional glyoxylate cycle protein
- Trifunctional enzyme subunit alpha, mitochondrial
- Enoyl-CoA Hydratase
Sequence:
MLSSSGHAIRRGITTSAALSNKHAFIVGAARTPIGSFRSSLSSVTAPELASVAIKAALERGAVKPSSIQEVFLGQVCQANAGQAPARQAALGAGLDLSVAVTTVNKVCSSGLKAIILAAQQIQTGHQDFAIGGGMESMSQVPFYVQRGEIPYGGFQVIDGIVKDGLTDAYDKVHMGNCGEKTSKEMGITRKDQDEYAINSYKKSAKAWENGNIGPEVVPVNVKSKKGVTIVDKDEEFTKVNFDKFTSLRTVFQKDGTITAANASTLNDGAAAVIVASQEAVSEQSLKPLARILAYGDAATHPLDFAVAPTLMFPKILERAGVKQSDVAQWEVNEAFSCVPLAFIKKLGVDPSLVNPHGGAVSIGHPIGMSGARLITHLVHTLKSGQIGVAAICNGGGGSSGMVIQKL
Protein: Esr2a protein (Estrogen receptor 2a) (Estrogen receptor beta2) (Q7ZU32)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR002527}.
Interaction partners:
- Aromatase
- G-protein coupled estrogen receptor 1
- Vitellogenin 1
- Cholesterol side-chain cleavage enzyme, mitochondrial
- Cytochrome P450, family 17, subfamily A, polypeptide 1
Sequence:
MSEYPEGDSPLLQLQEVDSGRVGGHILSPIFNSSSPSLPVENHPICIPSPYTDLGHDFSTLPFYSPALLGYSTSPLSDCSSVRQSLSPTLFWPPHSHVSSLTLQQQSRLQQNHATSGTWTEHTPHDHVEEENSKPLVKRVADTEETSVSLRGKADMHYCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMMKCGLRRDRSSYQQRGAQQKRLVRFSGRMRMTGPRSQEIKSIPRPLSGNEVVRISLSPEELISRIMEAEPPEIYLMKDMKKPFTEANVMMSLTNLADKELVHMISWAKKIPGFVELSLFDQVHLLECCWLEVLMLGLMWRSVNHPGKLIFSPDLCLSRDESSCVQGLVEIFDMLLAATSRFRELKLQREEYVCLKAMILLNSNMCLGSSEGGEDLQSRSKLLCLLDSVTDALVWAISKTGLSFQQRSTRLAHLLMLLSHIRHVSNKGMDHLHCMKMKKMVPLYDLLLEMLDAHIMHSSRLSHSGPRAPAAHKDNKSVQEAFPCSSQHGP
Protein: Probable oxidoreductase (Q9I0Z1)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Transcriptional regulator MexT
- Resistance-Nodulation-Cell Division
- Efflux pump membrane transporter
- Multidrug efflux outer membrane protein OprN
Sequence:
MSRVIRFHQFGPPEVLKCEELPTPAPAAGEVLVRVQAIGVSWKDVLWRQNLAPEQAALPSGLGFELAGEVLAVGAGVGDLPLGSRVASFPAHTPDHYPAYGDVVLMPRAALAVYPEVLTPVEASVYYTGLLVAYFGLVDLAGLKAGQTVLITEAARMYGPVSIQLAKALGARVIASTKSAEEREFLREQGADKVVVTDEQDLVLEVERFTEGKGVNVILDELGGPQMTLLGDVSATRGKLVLYGCNGGDESAFPACAAFKKHLQFYRHCLMDFTGHPEMGLERNDESVSKALAHIEQLTRDRLLKPVVDRVFEFDQVVEAHRYMETCPKRGRVVIHVAD
Protein: Zinc finger protein 461 (Gonadotropin-inducible ovary transcription repressor 1) (GIOT-1) (Q8TAF7)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- TOX high mobility group box family member 2
- Zinc finger protein 615
Sequence:
MAHELVMFRDVAIDVSQEEWECLNPAQRNLYKEVMLENYSNLVSLGLSVSKPAVISSLEQGKEPWMVVREETGRWCPGTWKTWGFHNNFLDNNEATDINADLASRDEPQKLSPKRDIYETELSQWVNMEEFKSHSPERSIFSAIWEGNCHFEQHQGQEEGYFRQLMINHENMPIFSQHTLLTQEFYDREKISECKKCRKIFSYHLFFSHHKRTHSKELSECKECTEIVNTPCLFKQQTIQNGDKCNECKECWKAFVHCSQLKHLRIHNGEKRYECNECGKAFNYGSELTLHQRIHTGEKPYECKECGKAFRQRSQLTQHQRLHTGEKPYECKQCGKAFIRGFQLTEHLRLHTGEKPYECKECGKTFRHRSHLTIHQRIHTGEKPYECRECGKAFSYHSSFSHHQKIHSGKKPYECHECGKAFCDGLQLTLHQRIHTGEKPYECKECGKTFRQCSHLKRHQRIHTGEKPHECMICGKAFRLHSHLIQHQRIHTGEKPYECKECGKAFSYHSSFSHHQRIHSGKKPYQCGKAFNHRLQLNLHQTLHTGEKPVRFPLLPPHPSLAS
Protein: Leucine-rich repeat LGI family member 3 (Leubrin) (Leucine-rich glioma-inactivated protein 3) (Q8K406)
Organism: Mus musculus (Mouse)
Function: May participate in the regulation of neuronal exocytosis.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q8N145}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000269|PubMed:18760330}. Synapse, synaptosome {ECO:0000269|PubMed:18760330}. Cell projection, axon {ECO:0000269|PubMed:35948005}. Note=Found in the synaptosomal membrane fraction. Within peripheral myelinated axons, LGI3 is highly expressed at the juxtaparanodal membrane and colocalizes with the voltage-gated potassium channels Kv1.1 (KCNA1) and Kv1.2 (KCNA2), and CNTNAP2, DLG4, ADAM22 and ADAM23 (PubMed:35948005). {ECO:0000269|PubMed:35948005}.
Interaction partners:
- Disintegrin and metalloproteinase domain-containing protein 23
- Disintegrin and metalloproteinase domain-containing protein 22
Sequence:
MAGLRARRGPGRRLLVLSTLGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKSVPKNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFIGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNALNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDGQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWFFAVADSSKAGATSLYRWHQNGFYSHQALHAWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRSQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGHRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA
Protein: UPF0764 protein C16orf89 (Q6UX73)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000269|PubMed:20578903}.
Interaction partners:
Sequence:
MASLGLLLLLLLTALPPLWSSSLPGLDTAESKATIADLILSALERATVFLEQRLPEINLDGMVGVRVLEEQLKSVREKWAQEPLLQPLSLRVGMLGEKLEAAIQRSLHYLKLSDPKYLREFQLTLQPGFWKLPHAWIHTDASLVYPTFGPQDSFSEERSDVCLVQLLGTGTDSSEPCGLSDLCRSLMTKPGCSGYCLSHQLLFFLWARMRGCTQGPLQQSQDYINLFCANMMDLNRRAEAIGYAYPTRDIFMENIMFCGMGGFSDFYKLRWLEAILSWQKQQEGCFGEPDAEDEELSKAIQYQQHFSRRVKRREKQFPDSRSVAQAGVQWRNLGSLQPLPPGFKQFSCLILPSSWDYRSVPPYLANFYIFLVETGFHHVAHAGLELLISRDPPTSGSQSVGL
Protein: Cytochrome b-c1 complex subunit 7 (Q9VXI6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004443}; Matrix side {ECO:0000256|ARBA:ARBA00004443}.
Interaction partners:
- Cytochrome b-c1 complex subunit 6
- Mitochondrial-processing peptidase subunit beta
- GEO11443p1
- Cytochrome b-c1 complex subunit 8
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome b-c1 complex subunit 9
- AT02348p
- Cytochrome c oxidase subunit 5B, isoform A
Sequence:
MSNYIARKGPAVLSNLGRWAYNLSGFNQYGLHRDDCLYENEDVKEAVRRLPRKLYDERNYRIMRALHLSMTKTILPKEQWTKYEEDVKYLEPYLKEVVKEREEREDWEKIH
Protein: Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-) (Q9UTA8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable methyltransferase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MAEQIDLKTFKTDVADYEAARPEYPIGITDWITDEFLIDETSIILELGAGTGKFTPRIIASHPKEIIAVDVYPEMLDVLRKKFPNVDCRAGSAMAIPLEDESVDLVLCAQCFHWFANEEAMKEIYRVLKPNGKLGLVWNTRDDTVPWIEKVSKILGRYRKDAPSFVSWKWAELFPGHGFGKLRYCAFPFSRCLTVEELHTLMNSFSFIYKLPEEEKEKVHAELDEIAKTIPRVQNTDQIKLCYQTMAFSSEKEPAK
Protein: THO complex subunit 2 (Low dye-binding protein 5) (THO complex subunit RLR1) (Zinc-regulated gene 13 protein) (P53552)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase. It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:11060033, ECO:0000269|PubMed:14562095}.
Interaction partners:
- ATP-dependent RNA helicase SUB2
- RNA annealing protein YRA1
- THO complex subunit THP2
- THO complex subunit MFT1
- THO complex subunit HPR1
- Protein TEX1
- Nuclear cap-binding protein subunit 2
- Serine/arginine
- Serine/arginine
- mRNA export factor MEX67
Sequence:
MAEQTLLSKLNALSQKVIPPASPSQASILTEEVIRNWPERSKTLCSDFTALESNDEKEDWLRTLFIELFDFINKNDENSPLKLSDVASFTNELVNHERQVSQASIVGKMFIAVSSTVPNINDLTTISLCKLIPSLHEELFKFSWISSKLLNKEQTTLLRHLLKKSKYELKKYNLLVENSVGYGQLVALLILAYYDPDNFSKVSAYLKEIYHIMGKYSLDSIRTLDVILNVSSQFITEGYKFFIALLRKSDSWPSSHVANNSNYSSLNEGGNMIAANIISFNLSQYNEEVDKENYERYMDMCCILLKNGFVNFYSIWDNVKPEMEFLQEYIQNLETELEEESTKGVENPLAMAAALSTENETDEDNALVVNDDVNMKDKISEETNADIESKGKQKTQQDILLFGKIKLLERLLIHGCVIPVIHVLKQYPKVLYVSESLSRYLGRVFEYLLNPLYTSMTSSGESKDMATALMITRIDNGILAHKPRLIHKYKTHEPFESLELNSSYVFYYSEWNSNLTPFASVNDLFENSHIYLSIIGPYLGRIPTLLSKISRIGVADIQKNHGSESLHVTIDKWIDYVRKFIFPATSLLQNNPIATSEVYELMKFFPFEKRYFIYNEMMTKLSQDILPLKVSFNKAEREAKSILKALSIDTIAKESRRFAKLISTNPLASLVPAVKQIENYDKVSELVVYTTKYFNDFAYDVLQFVLLLRLTYNRPAVQFDGVNQAMWVQRLSIFIAGLAKNCPNMDISNIITYILKTLHNGNIIAVSILKELIITVGGIRDLNEVNMKQLLMLNSGSPLKQYARHLIYDFRDDNSVISSRLTSFFTDQSAISEIILLLYTLNLKANTQNSHYKILSTRCDEMNTLLWSFIELIKHCLKGKAFEENVLPFVELNNRFHLSTPWTFHIWRDYLDNQLNSNENFSIDELIEGAEFSDVDLTKISKDLFTTFWRLSLYDIHFDKSLYDERKNALSGENTGHMSNRKKHLIQNQIKDILVTGISHQRAFKKTSEFISEKSNVWNKDCGEDQIKIFLQNCVVPRVLFSPSDALFSSFFIFMAFRTENLMSILNTCITSNILKTLLFCCTSSEAGNLGLFFTDVLKKLEKMRLNGDFNDQASRKLYEWHSVITEQVIDLLSEKNYMSIRNGIEFMKHVTSVFPVVKAHIQLVYTTLEENLINEEREDIKLPSSALIGHLKARLKDALELDEFCTLTEEEAEQKRIREMELEEIKNYETACQNEQKQVALRKQLELNKSQRLQNDPPKSVASGSAGLNSKDRYTYSRNEPVIPTKPSSSQWSYSKVTRHVDDINHYLATNHLQKAISLVENDDETRNLRKLSKQNMPIFDFRNSTLEIFERYFRTLIQNPQNPDFAEKIDSLKRYIKNISREPYPDTTSSYSEAAAPEYTKRSSRYSGNAGGKDGYGSSNYRGPSNDRSAPKNIKPISSYAHKRSELPTRPSKSKTYNDRSRALRPTGPDRGDGFDQRDNRLREEYKKNSSQRSQLRFPEKPFQEGKDSSKANPYQASSYKRDSPSENEEKPNKRFKKDETIRNKFQTQDYRNTRDSGAAHRANENQRYNGNRKSNTQALPQGPKGGNYVSRYQR
Protein: Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS) (Q9U1Q4)
Organism: Caenorhabditis elegans
Interaction partners:
- Probable elongation factor 1-gamma
- Leucine--tRNA ligase
- Methionine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase
- Probable arginine--tRNA ligase, cytoplasmic
- Threonine--tRNA ligase, cytoplasmic
- valine--tRNA ligase
- Probable glutamine--tRNA ligase
- Probable arginine--tRNA ligase, mitochondrial
- Isoleucine--tRNA ligase, cytoplasmic
Sequence:
MSDPAGNRPKTEKELKKEAEKAAKLAKFEEKQKKLAEKKAAASDKPVKEAKAKKEQTVEAAEPVDQTPTGQRKKIDGEIPAAYFPGYVESGWYSWWEKEGFFKPEYIDKLNPGSNPADSFTVCIPPPNVTGNLHVGHALATTVEDTITRFNRMHGKRTLFNPGCDHAGIATQVVVEKRLKRERGLTRHDLGRDRFNQEVWHWKNEKGDVIYDQFRKLGASVDWDRAVFTMDPKMCRAVTEAFIRMHESGTIYRSNRLVNWSCALRSAISDIEVDKKELTGSTLIAVPGYDKKIEFGVLNSFAYKIQGSDEEIVVSTTRIETMLGDSGVAVHPDDQRYKHLVGKQCIHPFIPTRNLPIFADSFVEMEFGTGAVKITPAHDHNDYEVGIRQNLPFHNCITDDGLISQGCGEFSGMKRFDARTAVIEALKEKGLYRGKEDNPMVVPTCSRSKDVIEPILKPQWYVKCAHMAEKAVAAVANGDLQIIPEFHKATWNRWLESSRDWCISRQLWWGHRIPAYYISFADGREQPLPEENYWVSARTEQEALAKAAQKFQVPEAEILLKWDEDVLDTWFSSGMWPFAVFGWPDATKDMDLFFPGAVLETGHDILFFWVARMVFMAQELTGKLPFKEILLHAMIRDAHGRKMSKSLGNVIDPLDVIRGISLNDLQAQLLGGNLDEKEIAVAKEGQARDYPDGIPECGVDALRFALLSYTSQGRDINLDVLRVHGYRKFCNKLWQVVRFALARISDKPEQKPTFEINLKSATPTDLWILSRLAKAVKETNEALKAYNFTQATTVTYNFWLYDFCDVYVETIKPVLYGDNTTLRQVAISVLHKCIDTGLRLISPLMPFISEELWQRMPRLDDSDYTSPSIIVAQYPLTQKYEKYQNEKLEAAFEFAQELIGKVRSLRADYDLKKTKITMQILSETPEDESMLNDISAVITTLTFSEKVSILNKCESDKIEKGSAHIACGGRCQVYINLTGIIDVPKEIEKLGAKLQKNQISVKKIGDIQSSADYEQKVPVDIRALDQEKKATLEKEIENITAAIAQLKALN
Protein: Esterase-6 (Est-6) (EC 3.1.1.1) (Carboxylic-ester hydrolase 6) (Carboxylesterase-6) (P08171)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transferred from the ejaculatory bulbs of males to the female genitals upon copulation, plays an important role in the reproductive biology.
Subcellular location: Secreted.
Interaction partners:
- GH07829p
- Beta-glucuronidase
- Esterase P
- Beta-glucuronidase
- Cytidine deaminase
- cytidine deaminase
- Cytidine deaminase
- Phosphoglucomutase 1
- UDP-glucuronosyltransferase
Sequence:
MNYVGLGLIIVLSCLWLGSNASDTDDPLLVQLPQGKLRGRDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFENFVRDVEMRPDEQIISRNFINMLADFASSDNGSLKYGECDFKDNVGSEKFQLLAIYIDGCQNRQHVEFP
Protein: ATP-dependent lipid A-core flippase (EC 7.5.2.6) (Lipid A export ATP-binding/permease protein MsbA) (P60753)
Organism: Escherichia coli O157:H7
Function: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01703}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01703}.
Interaction partners:
- Lipopolysaccharide export system permease protein LptF
- Lipopolysaccharide export ABC permease
- Lipopolysaccharide export system ATP-binding protein LptB
- Vitamin B12 import ATP-binding protein BtuD
- Spermidine/putrescine import ATP-binding protein PotA
- Iron
- Spermidine/putrescine transport system permease protein PotB
- Maltose/maltodextrin import ATP-binding protein MalK
- D-methionine transport system permease protein MetI
- D-methionine-binding lipoprotein MetQ
Sequence:
MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ
Protein: Protein DFG16 (Extracellular mutant protein 41) (Zinc-regulated gene 11 protein) (Q99234)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in invasion during filamentous growth.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- pH-response regulator protein palI/RIM9
- pH-response regulator protein palH/RIM21
- pH-response regulator protein palF/RIM8
- pH-response regulator protein palA/RIM20
- pH-response transcription factor pacC/RIM101
- Calpain-like protease 1
- Uncharacterized protein YGR122W
Sequence:
MIIRLHFYYLLTLVYHLGLVGAYEKAARKRIQPPDLIPGPPGHKLGDERPPHYDHRPPYKKHIDNIPAYNLTDLIDDKLLNKYENSCTVNVLTGGFISLASNSWHLRAYNYTLNYPSFLIRCDNGSANPNFSHVLQDFVYDINNKFNVQDDSSKYIGKDPFPLGMIMITFASGCICVATWMLFLVVLLLPSDNHNRRNKVVHVYVLFSAIIRTVFLNETIAVIFDSQYHDDYQDASQFESFIVETAPYKICELVANILSDINWIYIVHYLQSNYGKPTWNWIPFKMKKGTHIIITVGCFLSLADNILFANLLWRKNLVVLKVFYKLIELLIYTIFISIICYFTWHNFAYILLPKTAEINTDGKCKTKLRILWENYHETIPLLAYNILIFILFYFTTIFFAAFTKHVRGWTFNFVHLLKVLITVNVWGLIGVLEKRELHISKKTVLGRKINNRDKFFANPTVNYYGEDLGKHLSAITLNRDLNTTKSNTTSHDSSSLVGSPSPTWKSPIERIRDRRRRHKIMKSENKFGQNPSFGSKSNGKPNTKTTLSKYRQLLRKPRRKTNSYEPKNGIGQNKEGSTVRPGADKHIRDSNYLATDISDNESMETELRTNHIYNYENSD
Protein: VRK serine/threonine kinase 3 (M0QXD7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MISFCPDCGKSIQAAFKFCPYCGNSLPVEEHVGSQTFVNPHVSSFQGSKRGLNSSFETSPKKVKWSSTVTSPRLSLFSDGDSSESEDTLSSSERSKGSGSRPPTPKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSLEALPTGTVLTDKSGRQWKLK
Protein: Fibulin-2 (FIBL-2) (P37889)
Organism: Mus musculus (Mouse)
Function: Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN.
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- Fibronectin
- Basement membrane-specific heparan sulfate proteoglycan core protein
- Fibrillin-1
- Elastin
- Aggrecan core protein
- Microfibrillar-associated protein 5
- Vitronectin
- Versican core protein
- Microfibrillar-associated protein 2
- Collagen alpha-1
Sequence:
MLLQESAGVWLALALVTALTPSPSMAVPWQDCTGAECPLLENCIEEALEPGACCATCVQQGCACEGYQYYDCVQGGFVDGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVGCVHSGRKYAAGHTVHLSSCRACHCPDAGGELICYQLPGCHGNFSDAEEGDSERQYEDPYSYDQEVAEAEATTAIVNEVQAGAEGPPAALGGGNLPPSSIRVTPWPVALPRPTAAAALGPPAPVQAKARRVTLDTEEDEEEEEEETLVTEPPTAGSPGRLDSLPTRSPARPGFPVQEKEAEAKAGPEENLIPDAQVTPRSVMQEGAAPLPRSGLAALSPSLATDSSSEDPVKPSDHPTLSTLPPDRAQVSPSPETPEEIPQHPQLLPRFRAEEDIDPNSVHSVPRGDLDGSTKDLIETCCAAGQQWAIDNDECQEIPENGAQSDICRIAQRQCCISYLKEKSCVAGVMGAKEGETCGAEDNDTCGVSLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPEAAPRRVSEMEMASREALSLGTEAELPNSLPGDDQDECLMLPGELCQHLCINTVGSYRCACFPGFELQGDGRTCRPDRGAPQLDTARESAPRSESAQVSPNTIPLPVPQPNTCKDNGPCRQVCRVVGDTAMCSCFPGYAIMADGVSCEDQDECLMGTHDCSWKQFCVNTLGSFYCVNHTVLCAEGYILNAHRKCVDINECVTDLHTCTRAEHCVNTPGSFQCYKALTCEPGYVLTDGECTDVDECVTGTHNCQAGFSCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLLEPCRSGFSCINTVGSYTCQRNPLVCGRGYHANEEGSECVDVNECETGVHRCGEGQLCYNLPGSYRCDCKPGFQRDAFGRTCIDVNECWVSPGRLCQHTCENTPGSYRCSCAAGFLLAADGKHCEDVNECETRRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCVNVPGSYQCACPEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRCLRFDCPPNYVRVSETKCERTTCQDITECQTSPARITHYQLNFQTGLLVPAHIFRIGPAPAFAGDTISLTITKGNEEGYFVTRRLNAYTGVVSLQRSVLEPRDFALDVEMKLWRQGSVTTFLAKMYIFFTTFAP
Protein: NHP2-like protein 1 (Fertilization antigen 1) (FA-1) (High mobility group-like nuclear protein 2 homolog 1) (Sperm-specific antigen 1) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed] (Q9D0T1)
Organism: Mus musculus (Mouse)
Function: Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P55769}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P55769}. Note=Concentrated in the dense fibrillar component of the nucleolus. {ECO:0000250|UniProtKB:P55769}.
Interaction partners:
- Nucleolar protein 58
- U4/U6 small nuclear ribonucleoprotein Prp31
- U3 small nucleolar RNA-interacting protein 2
- Nucleolar protein 56
- rRNA 2'-O-methyltransferase fibrillarin
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- U3 small nucleolar RNA-associated protein 15 homolog
- U4/U6.U5 tri-snRNP-associated protein 1
- U4/U6 small nuclear ribonucleoprotein Prp3
- U4/U6 small nuclear ribonucleoprotein Prp4
Sequence:
MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV