wanglab/gogpt-training-data huggingface dataset:
Protein: 48 related 2, isoform B (Q9VEY3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSRNQLPDSSSSPPISHLPFHNFDDDLINDLPSCIYAGQHQGGGATGGGGGSGGGGGSSGLRLSSNNLRHIQQHYMQHSGENLLDSSTNPMGVHNSGGGAPLMCNSPSASSSGGGCGNAGSATPGGAGGPNPGYGSVGAATASSYKMQRQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTSDLTARLSWINWENLGVHPGRRTLLTSLALSSEPMCGAHCGMP
Protein: Glycosyltransferase (EC 2.4.1.-) (F4IS54)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEKMRGHVLAVPFPSQGHITPIRQFCKRLHSKGFKTTHTLTTFIFNTIHLDPSSPISIATISDGYDQGGFSSAGSVPEYLQNFKTFGSKTVADIIRKHQSTDNPITCIVYDSFMPWALDLAMDFGLAAAPFFTQSCAVNYINYLSYINNGSLTLPIKDLPLLELQDLPTFVTPTGSHLAYFEMVLQQFTNFDKADFVLVNSFHDLDLHVKELLSKVCPVLTIGPTVPSMYLDQQIKSDNDYDLNLFDLKEAALCTDWLDKRPEGSVVYIAFGSMAKLSSEQMEEIASAISNFSYLWVVRASEESKLPPGFLETVDKDKSLVLKWSPQLQVLSNKAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQDVWKVGVRVKAEKESGICKREEIEFSIKEVMEGEKSKEMKENAGKWRDLAVKSLSEGGSTDININEFVSKIQIK
Protein: Alanyl-tRNA editing protein AlaX-M (AlaX-M) (Alanyl-tRNA deacylase AlaX-M) (O57848)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function: Functions in trans to edit the amino acid moiety from mischarged charged Gly-tRNA(Ala) and Ser-tRNA(Ala).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Alanyl-tRNA editing protein AlaX-S
- Valine--tRNA ligase
- Isoleucine--tRNA ligase
- Leucine--tRNA ligase
Sequence:
MINMTRKLYYEDAYLKEAKGRVLEIRDNAILLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGNWQLVGSGMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGDRRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE
Protein: dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) (P26391)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.
Interaction partners:
- dTDP-4-dehydrorhamnose 3,5-epimerase
- Glucose-1-phosphate thymidylyltransferase
- dTDP-4-dehydrorhamnose reductase
- Glucose-1-phosphate cytidylyltransferase
- dTDP-4-amino-4,6-dideoxygalactose transaminase
- Lipopolysaccharide biosynthesis protein RfbH
- CDP-glucose 4,6-dehydratase
- glucose-1-phosphate thymidylyltransferase
- dTDP-glucose 4,6-dehydratase
- Undecaprenyl-phosphate galactose phosphotransferase
Sequence:
MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANTQWVNNVKSGAYQSWIEQNYEGRQ
Protein: Fibroblast growth factor 23 (FGF-23) (Q9EPC2)
Organism: Mus musculus (Mouse)
Function: Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism (By similarity). Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity). Up-regulates EGR1 expression in the presence of KL.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q9GZV9}. Note=Secretion is dependent on O-glycosylation. {ECO:0000250|UniProtKB:Q9GZV9}.
Interaction partners:
- Klotho
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Polypeptide N-acetylgalactosaminyltransferase 3
- Beta-klotho
- Phosphate-regulating neutral endopeptidase PHEX
- Parathyroid hormone
- Fibroblast growth factor 8
Sequence:
MLGTCLRLLVGVLCTVCSLGTARAYPDTSPLLGSNWGSLTHLYTATARTSYHLQIHRDGHVDGTPHQTIYSALMITSEDAGSVVITGAMTRRFLCMDLHGNIFGSLHFSPENCKFRQWTLENGYDVYLSQKHHYLVSLGRAKRIFQPGTNPPPFSQFLARRNEVPLLHFYTVRPRRHTRSAEDPPERDPLNVLKPRPRATPVPVSCSRELPSAEEGGPAASDPLGVLRRGRGDARGGAGGADRCRPFPRFV
Protein: AP complex subunit sigma (Q57TU5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
- AP-3 complex subunit delta
- AP-3 complex subunit beta
- Mu-adaptin 3, putative
- AP-1 complex subunit gamma
- AP-4 complex subunit epsilon
- 60S ribosomal protein L7a
- Clathrin heavy chain
- Clathrin coat assembly protein, putative
- AP complex subunit sigma
- Mu-adaptin 4, putative
Sequence:
MIKAVIIINMVGKIRLLNVYEKEIPLSVQQELVQRVHSLISRRGADLCNFVDNFREWPTPDTRVVYRHYATLCFVFVVDSSESQLAILDLIQVFVEVLDRTFENVCELDLIFHSDKVQLLLMEMVMGGMVLETSREEVLRAVCDMQRLGNTKTGMGSSSSGYHY
Protein: Ubp4-interactor sfp47 (O14259)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the regulation of activity and recruitment of ubp4 to endosomes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:20838651}. Endosome {ECO:0000269|PubMed:20838651}.
Interaction partners:
- UBP9-binding protein bun107
- UBP9-binding protein bun62
- Ubiquitin thioesterase otu2
- Ubp5-interacting protein ftp105
- Ubiquitin carboxyl-terminal hydrolase 11
- Probable ubiquitin carboxyl-terminal hydrolase 1
- Putative ubiquitin thioesterase otu1
- Probable ubiquitin carboxyl-terminal hydrolase 7
- Ubiquitin carboxyl-terminal hydrolase 5
- Probable ubiquitin carboxyl-terminal hydrolase 9
Sequence:
MNSFSSNEYSTEISTEALNNWQQLVEQRISLELEYAAKLAKLTKSIKAIKQCAPLNDLTKQVCVELMQCNKKHLEASRYFQTHVKEFMKEYVDRENKFSNETISKSSAAALMTSMENFILFTNPVYHNKLQVPSKSDMEIANSLKITQPAEKNSGTANPISAYSLEHAELDERNNQLSEALSMLRLSPFVNNYYPSYQNRKDGKSLMENRGVVLSVDTVTSPISQSPKKLTPTTSPINSTSLSFVDAKKPGSKWPSQYDFPKKTKSTEIPFKTLPSLNINNERELTKHKLPIVKPKLAVFPSNQATASTLQLAPPPVQAIPTLRNPVNLDDKKESLLKYYATHPTITPDGFPIFAYVRALYAYKATLPSEIDLNVDDTLVVLNRQKDGWWKGLVVSPTVGRIGLFPSNYIEELEY
Protein: Longifolene synthase (EC 4.2.3.58) (Terpene synthase TPS-Lonf) (PgxeTPS-Lonf) (F2XFA0)
Organism: Picea engelmannii x Picea glauca (Hybrid white spruce)
Function: Terpene synthase (TPS) involved in the biosynthesis of sesquiterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens. Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to longifolene.
Interaction partners:
Sequence:
MAQISKCSSLSAELNESSIISHHHGNLWADDFIQSLKSSNGAPQYHKRAEKLVEEIKNLVVSEMKDCNDDLIRRLQMVDIFECLGIDRHFQHEIQVALDYVYRYWNELEGIGIGSRDSLIKDFNATALGFRALRLHRYNVSSDVLENFKNENGQFFCSSTVEEKEVRCMLTLFRASEISFPGEKVMDEAKAFTTEYLTKVLTGVDVTDVDQSLLREVKYALEFPWHCSLPRWEARSFIEICGQNDSWLKSIMNKRVLELAKLDFNILQCAHHRELQLLSSWWSQSDIAQQNFYRKRHVEYYLWVVIGTFEPEFSTCRIAFAKIATLMTILDDLYDTHGTLEQLKIFTEGVKRWDLSLVDRLPDYIKITFEFFLNTSNELIAEVAKTQERDMSAYIRKTWERYLEAYLQEAEWIAARHVPTFDEYMKNGISSSGMCILNLYSLLLMGQLLPDDVLEQIHSPSKIHELVELTARLVDDSKDFETKKAGGELASGIECYVKDNPECTLEDASNHLIGLLDLTVKELNWEFVRHDSVALCFKKFAFNVARGLRLIYKYRDGFDVSNQEMKTHIFKILIDPLT
Protein: Secreted transmembrane peptide 5 (Phytocytokine STMP5) (Precursor of secreted transmembrane peptide 5) (A0A1P8ANJ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:31001913}. Secreted, extracellular space, apoplast {ECO:0000269|PubMed:31001913}. Note=The precursor of STMP5 accumulates at the plasma membrane and is proteolytically cleaved to release the STMP5 in the apoplasm. {ECO:0000269|PubMed:31001913}.
Interaction partners:
- At1g67860/T23K23_29
- Protein RALF-like 33
- At1g67862/At1g67862
- Protein RALF-like 24
- Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 6
- At3g13845
- AT1G25275 protein
- AT4g05070 protein
- Small polypeptide DEVIL 10
- Transmembrane protein
Sequence:
MRLSVFYIFITRLAMTKNATKNEMGSKSPNIVALVLPLLLILYTLSSQVEVVESTGRKLAFWGNPIVWTPHSNSCGGSPASVFASSKWTTGRPCRRSRPPGTNIPVSDQSP
Protein: Ribosomal protein P1B (A0A1D8PRG5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein eS8
- Large ribosomal subunit protein eL21
- Large ribosomal subunit protein uL3
- 60S acidic ribosomal protein P0
- Small ribosomal subunit protein eS24
- Large ribosomal subunit protein uL30
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein eL30
Sequence:
MSTEASVSYAALILADAEQEITSEKLLAITKAAGANVDQVWADVFAKAVEGKNFKELLFSFAAAAPASGAAAGSASGAAAGGEAAAEEAAEEEAAEESDDDMGFGLFD
Protein: N-terminal kinase-like protein (SCY1-like protein 1) (E9PK59)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MWFFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLHVVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPELEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDEQGPIRCNTTVCLGKIGSYLSASTRHRVLTSAFSRATRDPFAPSRVAGVLGFAATHNLYSMNDCAQKILPVLCGLTVDPEKSVRDQAFKAIRSFLSKLESVSEDPTQLEEVEKDVHAASSPGMGGAAASWAGWAVTGVSSLTSKLIRSHPTTAPTETNIPQRPTPEGVPAPAPTPVPATPTTSGHWETQEEDKDTAEDSSTADRWDDEDWGSLEEAESVLAQQDDWSTGGQVSRASQVSNSDHKSSKSPESDWSSWEAEGSWEQGWQEPSSQEPPPDGTRLASEYNWGGPESSDKGDPFATLSARPSTQDRSRLSWPGRSARSGGGRWRPNAPRGRWPRAP
Protein: Isocitrate lyase (Q599M3)
Organism: Emericella nidulans (Aspergillus nidulans)
Interaction partners:
Sequence:
MLRSIPRRVPRRLPIFTTTATAGGPSRLAQRAFTCGYLRMSPSSLPPVQPPVSSTLPSDSYQLLSTADKAGDAEDALYEQQIKDVEAWWNSPRFEGIKRPYSAADVVSKRGSLQQTYPSSLMARKLFNLLNERAAENKPVHTMGAIDPVQMTQQAPNQEVLYVSGWACSSVLTTTNEVSPDFGDYPYNTVPNQVQRLFKAQQLHDRKHWDARRKMTPEQRKSTPYIDYMRPIIADGDTGHGGLTAVLKLAKLFAENGAAAVHFEDQMHGGKKCGHLAGKVLVPIGEHINRLVATRFQWDMMGVENLVIARTDSESGKLLSSAIDVRDHEFILGVTEESEPLAETLQAMEREGAAPSEIDAFELDWVKRHKLVTFDEAVDAHLEAEGAPQAARDAYKKRVKENPDLSITRRRELANDYTKTPVVWSCDIPRTREGFYHYRAGFPAATKRAKEFGPYADLLWVETGDPNVEKAAKLAGEVRAALPGKKLVYNLSPSFNWMGQGFDEASLKSFIWDLAQHGFVLQLISLAGLHSGATITAELSRAFKDEGMLAYVRLIQAREKELGVDVLTHQKWSGAPYMDGIVGAIQSGSSSSKSMGEGNTEKGF
Protein: POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brain-3B) (Brn-3B) (Q12837)
Organism: Homo sapiens (Human)
Function: Tissue-specific DNA-binding transcription factor involved in the development and differentiation of target cells. Functions either as activator or repressor modulating the rate of target gene transcription through RNA polymerase II enzyme in a promoter-dependent manner. Binds to the consensus octamer motif 5'-AT[A/T]A[T/A]T[A/T]A-3' of promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to an octamer site to form a ternary complex with ISL1; cooperates positively with ISL1 and ISL2 to potentiate transcriptional activation of RGC target genes being involved in RGC fate commitment in the developing retina and RGC axon formation and pathfinding. Inhibits DLX1 and DLX2 transcriptional activities preventing DLX1- and DLX2-mediated ability to promote amacrine cell fate specification. In cooperation with TP53 potentiates transcriptional activation of BAX promoter activity increasing neuronal cell apoptosis. Negatively regulates BAX promoter activity in the absence of TP53. Acts as a transcriptional coactivator via its interaction with the transcription factor ESR1 by enhancing its effect on estrogen response element (ERE)-containing promoter. Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to an octamer motif. Involved in TNFSF11-mediated terminal osteoclast differentiation (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:7691107}. Nucleus speckle {ECO:0000269|PubMed:19266028}. Cytoplasm {ECO:0000250|UniProtKB:Q63934}.
Interaction partners:
- Insulin gene enhancer protein ISL-1
- Transcription factor ATOH7
- Visual system homeobox 2
- Cellular tumor antigen p53
- Melanopsin
- GTP-binding protein Rit2
Sequence:
MMMMSLNSKQAFSMPHGGSLHVEPKYSALHSTSPGSSAPIAPSASSPSSSSNAGGGGGGGGGGGGGGGRSSSSSSSGSSGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHPSALAGTHHHHHHHHHHHHQPHQALEGELLEHLSPGLALGAMAGPDGAVVSTPAHAPHMATMNPMHQAALSMAHAHGLPSHMGCMSDVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAGI
Protein: Alpha-hemoglobin-stabilizing protein (Erythroid differentiation-related factor) (Erythroid-associated factor) (Q9CY02)
Organism: Mus musculus (Mouse)
Function: Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12066189}.
Interaction partners:
Sequence:
MAPFQSNKDLISTGIKEFNVLLDQQVFDDPLISEEDMVIVVHDWVNLYTNYYKKLVHGEQEEQDRAMTEFQQELSTLGSQFLAKYRTFLKSKEPPSNTLPSS
Protein: fumarate hydratase (EC 4.2.1.2) (Q385R3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- malate dehydrogenase
- Malate dehydrogenase
- Malic enzyme
- Malic enzyme
- Malate dehydrogenase
- Succinate dehydrogenase, putative
- malate dehydrogenase
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Citrate synthase
- fumarate hydratase
Sequence:
MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQLR
Protein: Late cornified envelope 1D (Q9D731)
Organism: Mus musculus (Mouse)
Interaction partners:
- Late cornified envelope 1B
- Late cornified envelope 1C
- KPRP N-terminal and LCE C-terminal like protein
- Late cornified envelope 1A1
- Late cornified envelope 3B
- Late cornified envelope 1A2
- Late cornified envelope 1E
- Late cornified envelope 1F
- EIG3
Sequence:
MSCQQSQQQCQPPPKCTPKCPPKCQTPKCPPKCPPKCPPKCPPVSSCCSLGSGGCCGSSSGGCCSSGGCCSSGGCCSSGGGGCCLSHHRPHRSLRRHRHSSGCCSSGGSSGCCGSSGGSSGCCGSSQQSGDCC
Protein: Cadherin 96Cb, isoform D (A0A0B4LHM7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Cadherin-86C
Sequence:
MRINHQWIYYAILSLCWFNKATLGAILDSRCYLEGGGSAESFLATEDLAVGSIIGKLRINGDANAETGDINLSLREKNAPVEIHPGTKELALSVELDKEGVRGPSSIYVNVICIRRHSTDPSFVIPVNVRVTDVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQFLNPLEGTLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPKFQRESYSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTIVQSQDAKYFRIHPHNGAISLLTPIGYADVANGATLVVKATQIDNPDRYALTTVQLTRPGSHSDLSTLAFVQKRFVMRIREDTAVGNRILALPTNKPGKHLKYVIPDPVNSQFFSVGSLGELVLAKPLDYEKMTKHEFQVLATDGMTNSTAELTLEVIDVNDWEPRFRETHYEFMVPKSSLQSRADSFEGVLIGKVEAADGDRNDKLELSLRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVHLIAIATDTGVPPRSTSVPVSVTMEGLTLARSGWNSNMLGMFGMIMGLFLMIIVALSCYIVRSKKQGKSASSGLGLGRNRVHSQAHSSVSSANLVTHEKLAGNGNGNGASVTSGGVSVLHMKHGGNITMANPMNNGLHHVASGASSSMALGSSAALLERERERERDRERQRESYAATVRIFLPGIVSRASANGQLFEEDEIEHDSLQTENNNRKVAATGVASGGVTTISTTPANAGSNLLSATDAMGSSENNLTVYF
Protein: SH3 domain-binding glutamic acid-rich-like protein 3 (Q5T123)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, ruffle membrane {ECO:0000256|ARBA:ARBA00004632}. Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSGLRVYSTSVTGSREIKSQQSEVTRILDGKRIQYQLVDISQDNALRDEMRALAGNPKATPPQIVNGDQYCGVWAGGRGGGGSVGRGL
Protein: Claudin (Q90XR9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, tight junction {ECO:0000256|RuleBase:RU060637}. Cell membrane {ECO:0000256|RuleBase:RU060637}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU060637}.
Interaction partners:
- Claudin a.
- Claudin
- Claudin-7-B
- Claudin b
- Uncharacterized protein LOC550497
- Claudin
- Tight junction protein 3
- Tight junction protein 1a
- Claudin
- Claudin-7-A
Sequence:
MVSMCREILGMCLAIIGFLGAIIICALPMWKVTAFIGANIVTAQTIWEGLWMNCVMQSTGQMQCKIYDSLLALPQDLQAARALVVIAIIVSFFALILGIAGGKCTNFVEREDAKAKVSIASGVIFIIAGVLVLVPVCWSANTIIRDFYNPLLTDAQRREMGASLYIGWGVAALLIIGGGILCSSCPPKDEKYNMKYSQPRSTATSRAYV
Protein: RIPOR family member 3 (Q96MK2)
Organism: Homo sapiens (Human)
Interaction partners:
- Ubiquitin-like protein FUBI
Sequence:
MSVRLRFLSPGDTGAVGVVGRSASFAGFSSAQSRRIAKSINRNSVRSRMPAKSSKMYGTLRKGSVCADPKPQQVKKIFEALKRGLKEYLCVQQAELDHLSGRHKDTRRNSRLAFYYDLDKQTRCVERHIRKMEFHISKVDELYEDYCIQCRLRDGASSMQRAFARCPPSRAARESLQELGRSLHECAEDMWLIEGALEVHLGEFHIRMKGLVGYARLCPGDHYEVLMRLGRQRWKLKGRIESDDSQTWDEEEKAFIPTLHENLDIKVTELRGLGSLAVGAVTCDIADFFTTRPQVIVVDITELGTIKLQLEVQWNPFDTESFLVSPSPTGKFSMGSRKGSLYNWTPPSTPSFRERYYLSVLQQPTQQALLLGGPRATSILSYLSDSDLRGPSLRSQSQELPEMDSFSSEDPRDTETSTSASTSDVGFLPLTFGPHASIEEEAREDPLPPGLLPEMAHLSGGPFAEQPGWRNLGGESPSLPQGSLFHSGTASSSQNGHEEGATGDREDGPGVALEGPLQEVLELLRPTDSTQPQLRELEYQVLGFRDRLKPCRARQEHTSAESLMECILESFAFLNADFALDELSLFGGSQGLRKDRPLPPPSSLKASSRELTAGAPELDVLLMVHLQVCKALLQKLASPNLSRLVQECLLEEVAQQKHVLETLSVLDFEKVGKATSIEEIIPQASRTKGCLKLWRGCTGPGRVLSCPATTLLNQLKKTFQHRVRGKYPGQLEIACRRLLEQVVSCGGLLPGAGLPEEQIITWFQFHSYLQRQSVSDLEKHFTQLTKEVTLIEELHCAGQAKVVRKLQGKRLGQLQPLPQTLRAWALLQLDGTPRVCRAASARLAGAVRNRSFREKALLFYTNALAENDARLQQAACLALKHLKGIESIDQTASLCQSDLEAVRAAARETTLSFGEKGRLAFEKMDKLCSEQREVFCQEADVEITIF
Protein: Protein TMA108 (EC 3.4.11.-) (108 kDa translation machinery-associated protein) (P40462)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Putative zinc aminopeptidase which may be involved in ribosome biogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Nascent polypeptide-associated complex subunit beta-1
- Nascent polypeptide-associated complex subunit alpha
- Nascent polypeptide-associated complex subunit beta-2
- Clustered mitochondria protein 1
- Ribosome biogenesis protein SSF1
Sequence:
MSDNLLSLENPVVPSHYELRLEIDPKQSSPNFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSKDLIVLSAHATIGSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGKIRDIKTHHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQYKAVSNTPVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGDRTIPVSIYAPWDIANAAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKFLKSQNITNFVSSWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDVPYQVPLFGVLPDGKMDTKNVLLTDRTLKFDYPILVINHLAQGYYRVSYESEECYALINDKITEETLSEIDLRKIFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDRASLTSSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLFLNKNSAKCAELCQIYFKHLLQGPRSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQNSSETAMLIQNGAIESLGFCLDSDIVKKTLNFITSNIESEGMELALFGFNYNFKKRLNKNEKPQDQVVRETIWEWYMGNFDQWARKATRKGTTTGDHLHKALRSISLIIFQMFVADEPQKIEKFINLEKEKLGQSLLSLDDIWASVQQDEESRKTIRRDLASLV
Protein: F-box/kelch-repeat protein At4g19330 (Protein COLD TEMPERATURE GERMINATING 10) (O65704)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in seed germination.
Interaction partners:
- BTB/POZ domain-containing protein At2g46260
Sequence:
MAYLSFKSNMERTPRESNTPCPPPQPSPSLFSSLPDDIVLNILARISTSYYQTLSLVSKTFRLLILSKELDMERSYLGTRKPCVYVCLQSPTHPFDRRWFGLWIKPYDHQPLTHWTIDIKCTGHWLLPMPSPYSRCLQIVHETVGSETYEIGGQNMTPSTDVWVYDKLIGKQRKAPSMMVARKNAFTCVLDGKLYVMGGCEADESTHWAEVFDPKTQTWEALPDPGVELRYSSVKNIQTKQGKVYVRSNKKNFVYLIKECMWEVAEENLGESTCEIENVCYCYSNKRYWWYDAKCEEWRLVKGVSGLYEYYKTDSEIGNYGGKLVVFWDRAVSRLTATKEIWCAMISLEKGHDGEIWGHIEWLDAVLIAPRSYALSHCMDFLQ
Protein: LD10453p (Lnk, isoform A) (Lnk, isoform B) (Lnk, isoform C) (Q7K137)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGGNSTGANTSAFSAGGYIGPTSASSHHSLGTSSAAAAAAAGSDLIPAPIGTGNAMGVSSYAYGGTSWEEFCERHARVAASDFAKACITYINGNLPPEEARNIQHRSFAQKFVESFSAHYDTEFFKRRSTLKSGAGSLDFEEEHEVPKLLSKSLLRRLSFKGLRKGKAFFHKNSDDLDGSGGSGKQSKTKLAKIVVECRKEGTVNNLTPESLDQPTGSQKWEKCRLVLVKAVGGYMLEFYTPHKATKPRSGVFCFLISEARETTALEMPDRLNTFVLKADNNMEYVIEAESAEEMRSWLATIRYCMRTPPTQQPTIESDGVMASAMQTSPTLPSPNPIGGIQNPQYQQQRGSNGNLVGGGAPLTSSLSADSALGQGGATSASELNVINELGTSPTSGPPDIPVRPHRGEQRLSASSNFDGIEGTENDADVADLTAEMSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTISEKGQCRVQHLWFPSIQEMLEHFRHNPIPLESGGTSDVTLTEWVHSHSRLNDPTTAANHDSGQLNDLSTNGNGNGNGNGYDNGQGSSTASNAAGGTASGAAGGGHPSPRHCNEVITMNLSVRLKTNEIELPQEPTHVYFPEQVYFHLDPTTLTVHGSPPPAQNFLDQPHLRASNASLQAAAHHQAGSSGNRHPSDGGSNSGGAGGGSGSSGGAECTGRAVDNQYSFT
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (Q59U06)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR000909}.
Interaction partners:
- WD-repeat containing protein
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Phosphopantothenoylcysteine decarboxylase complex subunit
- Polyadenylation factor subunit 2
- Endoribonuclease YSH1
- Protein CFT1
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Cleavage and polyadenylation specificity factor subunit 2
- Type 1 protein phosphatase-activating protein
Sequence:
MGSNSSKSAPTLQRSDTNNSTRSTRSNRSIRSRRSISSIKDSQQQQSDSQQQQEEEEEQSQSQQRPQPILSRNNSATSENPILIRRNTNETLQTPNFSDTLSPHSHSQQQQQQPGSPLSTSMNGNTISRTSTNHSIISTTSHKSSSQQSNLPLKKETTTSSLSTNSNTIDIDSLIDKLLNAGFSGKRTKNVCLKNTEIELICASAREIFLSQPSLLELAPPVKVVGDVHGQYHDLIRIFSKCGFPPKTNYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKTWKLFIDTFNTLPIAAIVAGKIFCVHGGLSPVLNSMDEIRNIARPTDVPDFGLLNDLLWSDPADTINEWEDNERGVSYVFSKVAINKFLSKFNFDLVCRAHMVVEDGYEFFNDRTLVTVFSAPNYCGEFDNWGAVMGVSEDLLCSFELLDPLDSAALKQVMKKEKQERKKST
Protein: Uncharacterized protein C23H4.13c (O13954)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSSNSAVQSKSPLLPKENPPVKAFPDNIQVSSSLLSFLIYILYTFSISGLSTFVITKYYIRPQWLYTLALRRALIKLYYNFMDGFNKRTDTLQHRVDDKKILKTIEKWSCIKEKLRRVANITEQEQQCIPAESSLDLSIQAMKGVVNAELYQFGSQISGSLEFDTPIGNLQKQIVSLKSKMINI
Protein: Cell division protein FtsZ 1 (Q48327)
Organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Function: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells (By similarity). Binds GTP and shows GTPase activity, but only at high salt (2 M KCl) concentrations. Involved in division ring assembly directing the assembly, positioning and stabilization of FtsZ2 at the midcell envelope. Plays a role in defining cell shape.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00909, ECO:0000269|PubMed:33903747, ECO:0000269|PubMed:34103513, ECO:0000269|PubMed:8858586}. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane. {ECO:0000269|PubMed:33903747, ECO:0000269|PubMed:34103513, ECO:0000269|PubMed:8858586}.
Interaction partners:
- Protein translocase subunit SecE
- Transcription elongation factor Spt5
- D-aminoacyl-tRNA deacylase
- Cell division protein SepF
Sequence:
MDSIVGDAIDEAEAEDMGDESAQVDGAANINRSGTMTDDELKAVLKDLQTNITVVGCGGAGGNTVNRMHEEGIKGAKLVAANTDVQHLVEIGADTKILMGEQKTQGRGAGSLPQVGEEAALESQEEIYDAIEGSDMVFVTAGLGGGTGTGSAPVVAKAARESGALTIAIVTTPFTAEGEVRRTNAEAGLERLRDVSDTVIVVPNDRLLDAVGKLPVRQAFKVSDEVLMRSVKGITELITKPGLVNLDFADVKTVMERGGVAMIGLGESDSESKAQESVKSALRSPLLDVDISGANSALVNVTGGSDMSIEEAEGVVEEIYDRIDPDARIIWGTSVDDELEGMMRTMIVVTGVESPQIYGRNGEAQAHAEERLEDIDYVE