wanglab/gogpt-training-data huggingface dataset:
Protein: Sorcin (22 kDa protein) (CP-22) (CP22) (V19) (P30626)
Organism: Homo sapiens (Human)
Function: Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Subcellular location: Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
Interaction partners:
- Ryanodine receptor 2
- Presenilin-2
- Annexin A7
- Triadin
- Calmodulin-1
- Calmodulin-like protein 3
- Calmodulin-like protein 5
- Calmodulin-like protein 6
- Calmodulin-like protein 4
- Serine/threonine-protein kinase Nek8
Sequence:
MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV
Protein: F-box protein At1g70590 (Q94C27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein OS-9 homolog
- Derlin-2.1
- Derlin-1
- Derlin-2.2
- Probable diphthine methyl ester synthase
- Cysteine-rich receptor-like protein kinase 3
- Pentatricopeptide repeat
- MIF4G domain-containing protein
- At4g27620
- At4g12840
Sequence:
MKQRTWPCRSEGSRFSSLSFLKPHDKDKRSRISSINKATAKSTTSSRSSSSSSSSRPPSNEFGDFSMLPYDILMKIAAPFSHPNLQAASLVCKSWRDALKPLRESMLLIRWGKKYKHGRGGVRANLDKALDSFLKGAMRGSTLAMVDAGLVYWERGEKEKAVNLYRRASELGDAVGQCNLGIAYLQVQPSNPKEAMKWLKQSAENGYVRAQYQLALCLHHGRVVQTNLLEATKWYLKAAEGGYVRAMYNISLCYSVGEGLPQNRKLARKWMKRAADHGHSKAQFEHGLALFSEGEMLKSVLYLELAERGGEAAATPVKEVVHQQLSATFGGQAVHHAIHQANNWRPLPVTR
Protein: Serine/threonine-protein phosphatase 2A regulatory subunit sur-6 (Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit sur-6) (Serine/threonine-protein phosphatase 2A regulatory subunit B sur-6) (SUR-6/B55) (SUR-6/PR55) (G5EDR3)
Organism: Caenorhabditis elegans
Function: Probable regulatory subunit of serine/threonine phosphatase let-92. Together with let-92 and constant regulatory subunit paa-1, positively regulates centriole duplication during early embryonic cell divisions by preventing the degradation of sas-5 and kinase zyg-1. In addition, during vulva development, may play a role with phosphatase let-92 and regulatory subunit paa-1 in the induction of vulva cell precursors by positively regulating let-60/Ras-MAP kinase signaling, probably by promoting lin-45 activation. In intestinal epithelial cells, may play a role in the late secretory pathway probably by regulating the exocyst, a protein complex involved in targeting secretory vesicles to the plasma membrane.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21497766}.
Interaction partners:
- Probable serine/threonine-protein phosphatase PP2A regulatory subunit
- Serine/threonine-protein phosphatase 2A catalytic subunit
- Serine/threonine protein phosphatase 2A regulatory subunit
- Serine/threonine-protein phosphatase 2A regulatory subunit rsa-1
- Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1
- EF-hand domain-containing protein
- Serine/threonine-protein phosphatase 4 regulatory subunit 4
- mRNA stability protein
- Nuclear exosome regulator NRDE2
- Mob1/phocein
Sequence:
MVMEVDEPAVAATTSQNQPQEHANDFDMDTSEGPIENDETFEPVDQINWKFNQVKGNIDADVHTEADVISCVEFSHDGEYLATGDKGGRVVIFQRDQSGKYVKGVRSREYNVYSTFQSHEPEFDYLKSLEIDEKINQIRWLKKKNAANFILSTNDKTIKLWKISERERKIGDDAWNLPRTNRINTSSFRGRLQIPSIVPMELIVEASPRRVYGNAHTYHVNSISVNSDQETFLSADDLRVNLWNLEITNESFNIVDIKPANMEELTEVITAAEFHPTQCNWFVYSSSKGSIRLCDMRDRALCDAYAKIFEEPEDPQSRSFFSEIIASVSDVKFSHNGRYLLTRDYLTVKVWDLNMESQPVETYPVHNYLRTKLCALYENDSIFDKFECDWSGDDKHILTGSYHNLFRSYARGNNQDAKTWEARPQEPHSQLRSRFVVPSAKRKRNNLSSSGETTEEDLSSDQLQFDRKILHTAWHPKDNIIALAATNNLYIFSDV
Protein: PHD-type domain-containing protein (Q582U8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MDPAVGVFSPFHSVLDGKNSRINQALELATKVTVKEEPDTENGGGKAAIIKTPKENGSNPNGTLCGGCEKVYTTKKIPKGGTYLCKQCGERYISKSAAGHFPPNTLKCCPASVTEGTDGVVRCCACHSWYHCACLGIVDKTLKEYISLSTTKWYCMEPACCEKVLCEKLKRKR
Protein: Toxin Lqh4 (Lqh IV) (LqhIV) (Toxin IV) (P83644)
Organism: Leiurus hebraeus (Hebrew deathstalker scorpion) (Leiurus quinquestriatus hebraeus)
Function: Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (By similarity). Intracerebroventricular injection into mice induces immediate convulsions and urination followed by death. Is toxic to insects and mice.
Subcellular location: Secreted {ECO:0000269|Ref.1, ECO:0000305}.
Interaction partners:
Sequence:
GVRDAYIADDKNCVYTCGANSYCNTECTKNGAESGYCQWFGKYGNACWCIKLPDKVPIRIPGKCR
Protein: Synapsin [Cleaved into: Synapsin-1 (Syn1) (Syn1-S); Synapsin-2 (Syn2)] (Q24546)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a significant role in nervous system function, which is subtle at the cellular level but manifests itself in complex behavior.
Subcellular location: Synapse.
Interaction partners:
- Synaptotagmin 1
- Ras-related protein Rab-3
- Synaptosomal-associated protein 25
- Synaptobrevin
- Bruchpilot, isoform J
- Liprin-alpha, isoform E
- Rab3 interacting molecule, isoform F
- Syntaxin-1A
- Unc-13, isoform E
- Molybdenum cofactor synthesis protein cinnamon
Sequence:
MKRGFSSGDLSSEVDDVDPNSLPPAARPIQDQPTKPPVAGGPPNMPPPPAPGQPAGAAPELSLSFGAGKTPATAAPAPPRGVSAPTSPAKSRESLLQRVQSLTGAARDQGASILGAAVQSATQRAPAFSKDKYFTLLVLDDQNTDWSKYFRGRRLHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAYRSGTRVARSFRPDFVLIRQPPRDGSSDYRSTILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQLQRRLGRDGFPLIEQTFFPNPRDLFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVSGAGNDSHCYCTIEPYIDAKFSVHIQKIGNNYKAFMRKSITGNWKTNQGSAMLEQITLTEKYKSWVDEISELFGGMEVCGLSVVVAKDGREYIISACDSTFALIGDTQEEDRRQIADLVSGRMQNVCRPSMAQTGPGKLPSRSSVSSRAESPTDEGVAPTPPLPAGPRPAPMGGPPPIPERTSPAVGSIGRLSSRSSISEVPEEPSSSGPSTVGGVRRDSQTSQSSTISSSVSRAGQRPPQTQNSVVEDAEDTMKNLRKTFAGIFGDMXEIANKKRGRTASETSSGSGPGSVPSSAGPGSGFSSSFLGKQFSFAGKGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSVSDSRNTDTLTERAGAGYQPVTNYEQQERVNPFDKEPSKSGSAASIHTSSSSSISSSSISSRINRNGNAIQSPPPPAGPPPPPPTNVTAVGSNANSSSGYRNSFSSSLSKDKTSYGNYGSTTSVETITRMDTNTTNIGATATEAGEASGVTAITNISNSDGIVAPTTGTITTSVTTNDWRSAIGMRSASVYSAPAAVTTVLPGDTSGYDSNSIASQGEGLNNPSDLPSYTRPSYSRSESNASKHSDLDVIFGDSKTTPASYGNGKYTRAAGSISDADMIFGGPPSNYKTDRFGASKSMSMTSGGVGSGNGSGSGLGGYKIYDSIQNAAFSDFSDSGSMSSIGSHTKRWSASKEEDDELDLK
Protein: Gp15 (Q9MCS4)
Organism: Enterobacteria phage HK97 (Bacteriophage HK97)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
Interaction partners:
Sequence:
MEPLVVVFGIFGWMINLIVIFYLLRFSTRANEQVEALKEINKKQDAQIDLLIQVAHQRKDSL
Protein: Endoplasmin (EC 3.6.4.-) (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Q66HD0)
Organism: Rattus norvegicus (Rat)
Function: Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (By similarity).
Subcellular location: Endoplasmic reticulum lumen {ECO:0000269|PubMed:19343716}. Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:P41148}. Melanosome {ECO:0000250|UniProtKB:P14625}.
Interaction partners:
- Protein disulfide-isomerase A4
- Endoplasmic reticulum chaperone BiP
- DnaJ homolog subfamily B member 11
- Calreticulin
- Hypoxia up-regulated protein 1
- Protein disulfide-isomerase A6
- Calreticulin
- Protein disulfide-isomerase
- Calreticulin
- Protein disulfide-isomerase A3
Sequence:
MRVLWVLGLCCVLLTFGFVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDREKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEEPLEEDETAQEEKEEADDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPEAQVEEEPEEEPEDTTEDTTDDSEQDEEETDAGAEEEEEEQETEKEPTEKDEL
Protein: Syndecan-2 (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG) (CD antigen CD362) (P34741)
Organism: Homo sapiens (Human)
Function: Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Glypican-1
- Syndecan-4
- Syndecan-1
- Ezrin
- Trafficking protein particle complex subunit 4
- Peripheral plasma membrane protein CASK
- Fibronectin
- Syntenin-1
- Radixin
- Moesin
Sequence:
MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA
Protein: RNA helicase (EC 3.6.4.13) (F6QYI9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGSSHIGGLSINERRRSASLGLVMAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKN
Protein: RE63021p (Ras-associated protein 2-like, isoform A) (Ras-related protein 2-like protein) (O96692)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Recycling endosome membrane {ECO:0000256|ARBA:ARBA00004523}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004523}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004523}.
Interaction partners:
- Exchange protein directly activated by cAMP, isoform E
- Ral guanine nucleotide dissociation stimulator-like, isoform E
- non-specific serine/threonine protein kinase
- Dizzy isoform AII
Sequence:
MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFASMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAEGNALAQLWDCPFIEASAKDRINVNEVFATIVREMNLTQENRQKKNYCCCTLL
Protein: Putative annexin A2-like protein (Annexin A2 pseudogene 2) (Lipocortin II pseudogene) (A6NMY6)
Organism: Homo sapiens (Human)
Function: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}. Melanosome {ECO:0000250}. Note=In the lamina beneath the plasma membrane. In melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism. {ECO:0000250}.
Interaction partners:
Sequence:
MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNIVTNRDNAQRQDIVFSYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAQDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQRIQNKPLYFADQLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
Protein: Orexin receptor type 2 (Hypocretin receptor type 2) (A1YQE3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Hypocretin
- Serotonin N-acetyltransferase
- Histidine decarboxylase.
- Neuronal pentraxin IIb.
Sequence:
MSGISVQRACNSCFTSAQHLNSSADTISHSHAENEDDELLKYIWREYLHPKQYEWVLIAGYILVFLVSLVGNTLVCFAVWKNHHMRTVTNYFIVNLSFADILVTITCLPASLVVDITETWFFGQTLCKILPYLQTISVSVSVLTLSCIAQDRWYAICHPLKFKSTAKRARKSIVLIWLVSCIMMIPQAVVMESSSLMPELTNKTSLFTVCDEQWPDEIYPKVYHTCFFIVTYFAPLCLMVLAYIQICHKLWCQQIPGSSSVLQRQWKSLQCSAHAVGSGESVKVRTSTVSAEAKQVKARRKTARMLMVVLFVFALCYLPISILNIMKRVFGAFKNTGNRETVYAWFTFSHWLIYANSAANPIIYNFLSGKFREEFKAAFICQCSGRGETHKQRARGRTSTDSRKSLSTQVNNLDNISRISDQAV
Protein: CCHC-type domain-containing protein (J9VH01)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Interaction partners:
Sequence:
MSYNAPGGWGAPLTSGSDYNQPQQQVHGEDDGGWGGPPEEVEWAPPGAWPSDPVPKPAPAPVAEISQPTPVPEPTPAAVQAESVKTDASETQESEDGGWGGPAEVVNPASVPIPPSTAAASTASAASVSVPPSDVGADAGEIQEDNAGGWGGEPAKPSADKEDDWTAPVTGNVASNESGESQPVQKGVNDGGRKQPEAEPQQDNASPAPLKTSNSDNDAGGWGSPEPQQAIGGWDAPSSNDNAGGWGEPQPAVRAPSSQTSNSGGWNSQSQSTGNGNAGGWDNTDTQSVHSQRSQPSVQPARFSQQSGAQSQSRSINYGYGGGRDASDVGVYIPDAVVSRGPWDRPFVMPQSDNGWAGFAARRRGGAAGGAGRGGYGDIGGRQPQSQPQQQQGGWGAQPVQASGGWGNEPAQQTSGGWASEPVQQSSGGWDAEPTRQSSGEWGAEPTQTFSSNDADDGGWGADPAPIKSTSSSVSGSAPAPAPVPAPAPAQADDNAGGWGADHVPAANASSDDTGGWGSPEPAQRTPKAKTKVVDDASGWGAEPDAVPVQTNQAQSNDDTGGWGAEPASNESGDAGGWGDASQSQSQPQSNSGSGGWGDDAQSQSQSQSQSQPQSQSQNSGGWGDAPASSGENNWGSRSGGGASRQPSESGFGGGLQGGYSGGGGRGRGFGGECHHCGKAGHIARICPDAGYSGSLDDCFRCQQPGHMARECPNPFGGGDACFRCGQAGHFARECPGAYGGGGFGGSNGGFRAGFAPPVSGSNAVTNVTGATGWGFRKAFLSQNPNAGERNQDSWNSSNSNSGDGGGGWDNSNGSGNDRPARTSWKDDARSGHSALSRDRDLTGRSAHEQWESEKVTLPKHKQEILAGQSWFEGNDGTSLAAEAVVEDDSTSSGWGAMRAAKANQPKPKAEDDDGGWGGAPVPAQNQDEDDGGWGGAPVPLSSRGKEDDGGWGGNAGSNDGEWGGGPEATPKAQPARLKPQPSAQSQPQTGGRDAEPVQFQTQASSDDNAGGWGAEPASNGANDDAGGWGAPEPKQISRPSSGDGWGASEPAPVNNGGGGWGQQGGRGNFGGNESSETSVSSQAGRRPGVRTPWAERSAMRANQAGKWGHDGFEQLERDWQTRGRGGFGGRGRGAPRGRGGFGDGFGSRGDDRDNFQSRDNGWGARASASANDNGAFAPSASNVNVGGWDAAPAPVPAASNNDDGGWGSAPARVPAASSDNDDGGWGGEPTRVLAPAPAPAPAAPSSEDHGGWAGEPEKHSPAPASVAPVQESVSADGDGGWGGEPEKIEVARGPDPTPVSASKEESKPEEDDGGWGNEPEKVEAPVAPPPAPVEEPKAEPEDGGWGGEPEKVERPLEKRPVEAEQPESKADEGSKPVIKATVNPASELKPSSIAGSAKAESVSSKQDAEHHTPKSVASSLRESSAPPSQGASSPQPFAQPFTPRTVQNSLLFASPVERHISPAPSIVSAGYLDGRASPFTPGYISPLAAPGPYAIPAAAIGVPPVPAYSAPIPVIPAAVSPPIQPSGPPRYFEPAKSDSRVSIKTPNGAPVISPAGSNASLPTSPPVAHSGYYEVPHVPIGQEGYYHQAMNPYDSMSSHVNVPVGVAEQGMSGFVEGPDGAYYPVSQQAGYGYRPFGYGM
Protein: Chaperone protein DNAJ, putative (Q57Y02)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFVLCTVENMGKSNGCNPSGRKRRRGTENTNVPRVPLSLLRSPFADSVPKHVGHGVADAARNVVVGVGMGMSGLIAATIASGKEEGAVGVAKGLGAGIVTLAGGTLAGVVMGARQLGRGVMNTKAALQQTVRGRCYWCEIYGKWIDVHLDDMLADLPPTDDDIYRKSRKRKNKIMDWVKKSLSPDSNEEDAADADSTEQQDGELGEDFYSILGVGREATADEIRSAYRHKALLLHPDRNIGDADASQRFQRLLDAYNVLSDERCRIEYDTSGKVNPNRVGNGSYSNIEEILGARHWEPFIGRLGWTLHFTSRLYLDGELRKEMKNRRRLRLAKILLPLVDGDDATLEAARPAIVDAVCTRGGRSFMPLVAKQYAAVARQHLTRVPLRREIDRFRTSKWACISSMKLLTKTCVTTLYKAARKRLSGDQLINAALAFCQRDVQQSVGCAANLLLYDLSVTDEHRARRARMLVKISEMIMEICSTCSSSRSEATSQRL
Protein: Intracellular growth locus protein D (A0Q7I2)
Organism: Francisella tularensis subsp. novicida (strain U112)
Interaction partners:
Sequence:
MFLERIYWEDGLRLDSDILDKSNLSVLERLSTASYLPANLNKGIVSFDLDVESLQTGLILIKDLKLYLDEKNFVFYDKSYPLSLQIMTDKLSDEIPLFLNIREKVIEKNGVKYIYNQLSLSLEHSYGFKHSIQIALFRLDRGRLVPEIYDFPLLTLNHYYLGDIFVKLNRTVSELKSFNRFVFSASRSYASILLVFLINKLERELKFAESNRANSSPKQIFDLIDDIYSLIQLNLDKVEELDSIEFDFQKPLTKLNLLADRLLTLCEYRKINNFIRFELHGKKYICESFPEEFFVATRYYLFLKRKATAPANVRFENKNALRITSISRNKNIVTLSLSGVKLVDVECSMINFTTRFDNIDAIYEIQKGSEWDFILADSSAVFTAFEGSENFDFFIAFS
Protein: Immunodeficiency virus type 1, viral sample LC03.B05, V4C3V5 region (Q78524)
Organism: Human immunodeficiency virus type 1 (HIV-1)
Subcellular location: Virion membrane {ECO:0000256|ARBA:ARBA00004182}.
Interaction partners:
Sequence:
IVMHSFNCGGEFFYCNTTQLFNSTWNDTNQASNTEGNDTITLPCRIKQIINMWQEVGKAMYAPPIRGQIKCSSNITGLLLTRDGGTNETNTTETFRPGGGD
Protein: Acyltransferase (EC 2.3.1.-) (Q57ZE1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367023}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU367023}.
Interaction partners:
- Phospholipid:diacylglycerol acyltransferase-like protein
- Lipin, putative
- Phosphatidic acid phosphatase, putative
- Phosphatidic acid phosphatase protein, putative
- Monoglyceride lipase, putative
- Monoglyceride lipase, putative
- Lipase-like protein, putative
- Fungal lipase-type domain-containing protein
- Phosphatidic acid phosphatase alpha, putative
Sequence:
MLQKISAESASSYNAEFDPTPPATVEEMHRQLDLIIEACKRLEDLKTSGVRLTHREVLKLRKAYWLAVGETQKLRRDNSSRTGSLDGLETSETSTVDRPLSSGSSVQVNCSDDMGLKRQDAKALSCDEELVKLEKCVEERPEAHTFDVVHDLAEAMNTGWRIFGIPLERRLQTLAVSVFNFFAYVSLSLMLIVVMMVNQVTMVFVILYVLYIFTIGRPKHPLKKKDALMSLGIWHHFTNYFPVRLVVPQKVRCQFDSNKNYLFIYHPHGINSFGALSCFMLDTMNLRTILPGIRIHLQTLKLNFYIPFWRELAVAGGCGDASAQCIRDTLRKGPGECVALVVGGAKESLLARPKRNEVALQDRKGFVRIALQEGTSLVPVYGFGENDVYRIPRFAESNAWRRVEGLVRKYTRFAIPLVKGRGWFNYGFGLSPHRCPITVVFGEPIEVPRIPEPTAEEVQIWHAKYVEALQRLFSENHTVFAADSKGLVIR
Protein: succinate dehydrogenase (EC 1.3.5.1) (O53371)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable succinate dehydrogenase SdhD
- Succinate dehydrogenase flavoprotein subunit
- Succinate dehydrogenase 2 membrane subunit SdhC
- Fumarate reductase flavoprotein subunit
- Probable succinate dehydrogenase [iron-sulfur subunit]
- Succinate--CoA ligase subunit beta
- Succinate--CoA ligase subunit alpha
- Fumarate reductase subunit C
- Fumarate reductase subunit D
- Multifunctional 2-oxoglutarate metabolism enzyme
Sequence:
MSVEPDVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATGGWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDLLPKKKGKSLTVTVEPIRGLPVEKDLVVDMEPFFDAYRAIKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVFWHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTESCPRGIEVTKAIQEVKRALMFTR
Protein: Bifunctional dihydrofolate reductase-thymidylate synthase (Q582G3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ribonucleoside-diphosphate reductase
- Proliferating cell nuclear antigen
- thymidine kinase
- Methionyl-trna formyltransferase
- dTMP kinase
- dTMP kinase
- Aminomethyltransferase
- Rev7, putative
- tetrahydrofolate synthase
- Deoxyuridine triphosphatase, putative
Sequence:
MLSLTRILRKKIPVHELAGKISRPPLRPFSVVVASDEKGGIGDGGTIPWEIPEDMQYFRRVTTNLRGKNVKPSPSKRNAVVMGRKTWDSLPPKFRPLSNRLNVVLSRSATKEQLLAGIPDPIKRAEAANDVVAVNGGLEDALRMLVSKEHTSSIETVFCIGGGTIYKQALCAPCVNVLQAIHRTVVRPASNSCSVFFDIPAAGTKTLEGLELVRESITDERVSTGAGGKKYQFEKLVPRNSEEEQYLNLVGRIIDEGCTKCDRTGVGTRSLFGAQMRFSLRNNRLPLLTTKRVFWRGVCEELLWFLRGETNAKLLSDKGIHIWDGNGSRAFLDSRGLTDYDEMDLGPVYGFQWRHFGADYISCKEDSEGKGVDQIANIVKSLIENPDDRRMICTAWNPAALPRMALPPCHMMAQFYVSNGELSCMLYQRSCDMGLGVPFNIASYALLTFLMAKASGLRPGELVHTLGDAHVYSNHVEPCRKQLKRVPRPFPFIVFKQDKEFLEDFQESDIEVIDYSPYPVISMEMAV
Protein: Chromosomal protein D1 (P22058)
Organism: Drosophila melanogaster (Fruit fly)
Function: This satellite DNA-associated protein is a double-stranded DNA binding protein specific for tracts of pure at DNA. It may play a role in organizing the higher-order structure of euchromatin as well as heterochromatin.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Structural maintenance of chromosomes protein
- Structural maintenance of chromosomes protein
- Protein wings apart-like
- N-acetyltransferase eco
- FI11703p
- GH12158p
- CTD nuclear envelope phosphatase 1 homolog
- Stromalin-2
- LD34181p
- Nipped-B protein
Sequence:
MEEVAVKKRGRPSKASVGGKSSTAAVAAISPGIKKRGRPAKNKGSSGGGGQRGRPPKASKIQNDEDPEDEGEEDGDGDGSGAELANNSSPSPTKGRGRPKSSGGAGSGSGDSVKTPGSAKKRKAGRPKKHQPSDSENEDDQDEDDDGNSSIEERRPVGRPSAGSVNLNISRTGRGLGRPKKRAVESNGDGEPQVPKKRGRPPQNKSGSGGSTGYVPTGRPRGRPKANAAPVEKHEDNDDDQDDENSGEEEHSSPEKTVVAPKKRGRPSLAAGKVSKEETTKPRSRPAKNIDDDADDADSADQGQHNSKKESNDEDRAVDGTPTKGDGLKWNSDGENDANDGYVSDNYNDSESVAA
Protein: Putative colanic acid biosynthesis glycosyl transferase WcaA (P77414)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Putative colanic acid biosynthesis glycosyl transferase WcaC
- Putative colanic acid biosynthesis acetyltransferase WcaB
- Putative colanic acid biosynthesis glycosyl transferase WcaI
- Tyrosine-protein kinase wzc
- Putative colanic acid biosynthesis glycosyl transferase WcaE
- UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase
- Putative polysaccharide export protein Wza
- Putative colanic acid biosynthesis acetyltransferase WcaF
- Putative colanic acid polymerase
- GDP-mannose 4,6-dehydratase
Sequence:
MKNNPLISIYMPTWNRQQLAIRAIKSVLRQDYSNWEMIIVDDCSTSWEQLQQYVTALNDPRITYIHNDINSGACAVRNQAIMLAQGEYITGIDDDDEWTPNRLSVFLAHKQQLVTHAFLYANDYVCQGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQVFTWAWRFKECLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSSPKKFSGYFHFYRKHKDKFDRASKKYQLFTLYQIRNKRMTWRTLLTLLSVRNGKRLADGIRGR
Protein: SWIM-type domain-containing protein (Q38A57)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTAPLFSATDVPAVVTELALKRYAEYLVRRREKPEAAEGISGTTLEEALAPLYLLHGNTFTSAIGIAIHGAEHILRCVVRQAADSNEEEGKQQQHQDNQDGKFSTNRCAYMVGDHCILSLFYCSCRAYGYSCIKRQEASTCKHLLALRIALLLEENGLATDCIREKRITTEQFQEMVQRLL
Protein: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1) (Q8TDY4)
Organism: Homo sapiens (Human)
Function: Promotes cell proliferation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14654939}.
Interaction partners:
- ADP-ribosylation factor 6
- Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
- Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
Sequence:
MPEQFSVAEFLAVTAEDLSSPAGAAAFAAKMPRYRGAALAREEILEGDQAILQRIKKAVRAIHSSGLGHVENEEQYREAVESLGNSHLSQNSHELSTGFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAKMAKLEKERDRARVTGGIPGEVAQDMQRERRIFQLHMCEYLLKAGESQMKQGPDFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEDELQKLTQLRDSLRGTLQLESREEHLSRKNSGCGYSIHQHQGNKQFGTEKVGFLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPVKLTLLTCQVRPNPEEKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETPESLGSPASSSSLMSPLEPGDPSQAPPNSEEGLREPPGTSRPSLTSGTTPSEMYLPVRFSSESTRSYRRGARSPEDGPSARQPLPRRNVPVGITEGDGSRTGSLPASSVQLLQD
Protein: Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1) (P70512)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. The affinity of HNF-6-alpha and HNF-6-beta for DNA differs depending on the target sequence.
Subcellular location: Nucleus.
Interaction partners:
- Hepatocyte nuclear factor 3-beta
- Hepatocyte nuclear factor 1-beta
- Transcription factor SOX-9
- Nuclear receptor subfamily 1 group D member 1
- Hepatocyte nuclear factor 4-alpha
- Hematopoietically-expressed homeobox.
- CCAAT/enhancer-binding protein alpha
- Hepatocyte nuclear factor 1-alpha
- Neurogenin 3
- Hepatocyte nuclear factor 3-alpha
Sequence:
MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVGHRGSHLPPAHPRSMGMASLLDGGSGGSDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSGSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNDFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA