wanglab/gogpt-training-data huggingface dataset:
Protein: Homocysteine inducible ER protein with ubiquitin like domain 1 (F7F5G8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MVSSPFKRSSGWRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVRSPSKKPEASTKGAESTEQPDNTSQAQYPGDSSSDGLREREVLRNLPPSGWENVSRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFGPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQGGLDPEMEDPNRLPVGREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN
Protein: Protein NKG7 (G-CSF-induced gene 1 protein) (GIG-1 protein) (Granule membrane protein of 17 kDa) (GMP-17) (Natural killer cell protein 7) (p15-TIA-1) (Q16617)
Organism: Homo sapiens (Human)
Function: Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases (By similarity). Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection (By similarity). Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules (By similarity). Contributes to NK cell-mediated control of cancer metastasis (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:8570616}; Multi-pass membrane protein {ECO:0000269|PubMed:8570616}. Cytolytic granule membrane {ECO:0000269|PubMed:8570616}; Multi-pass membrane protein {ECO:0000269|PubMed:8570616}.
Interaction partners:
- Granzyme H
- Granulysin
- Granzyme A
- Granzyme K
- Perforin-1
- Granzyme B
- Natural killer cells antigen CD94
- T-cell surface glycoprotein CD8 alpha chain
- Cystatin-F
- Cathepsin W
Sequence:
MELCRSLALLGGSLGLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISGYIHVTQTFSIMAVLWALVSVSFLVLSCFPSLFPPGHGPLVSTTAAFAAAISMVVAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL
Protein: Juxtaposed with another zinc finger protein 1 (TAK1-interacting protein 27) (Zinc finger protein 802) (Q86VZ6)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2. Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (By similarity). Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity). Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity). Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:15302918}.
Interaction partners:
- Nuclear receptor subfamily 2 group C member 2
- Polycomb protein SUZ12
- Chromatin modification-related protein MEAF6
- MBT domain-containing protein 1
- WD repeat-containing protein 82
- Symplekin
- Bromodomain-containing protein 8
- Transformation/transcription domain-associated protein
- Enhancer of polycomb homolog 2
- YEATS domain-containing protein 4
Sequence:
MTGIAAASFFSNTCRFGGCGLHFPTLADLIEHIEDNHIDTDPRVLEKQELQQPTYVALSYINRFMTDAARREQESLKKKIQPKLSLTLSSSVSRGNVSTPPRHSSGSLTPPVTPPITPSSSFRSSTPTGSEYDEEEVDYEESDSDESWTTESAISSEAILSSMCMNGGEEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVRKPFKCRCGKSYKTAQGLRHHTINFHPPVSAEIIRKMQQ
Protein: Protein GOLVEN 9 [Cleaved into: GLV9p] (F4KB79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Signaling peptide (root growth factor) required during root gravitropism in a PIN2-traffic dependent manner. Regulates the pattern of root growth and lateral root development by modulating the length and the number of cortical cells in the root apical meristem (RAM), and the anticlinal asymmetric cell divisions in lateral root initiation cells.
Subcellular location: [GLV9p]: Secreted {ECO:0000250|UniProtKB:Q3E880}.
Interaction partners:
- Protein GOLVEN 3
- Protein GOLVEN 1
- Protein GOLVEN 7
- Protein GOLVEN 6
- Protein GOLVEN 10
- Protein GOLVEN 11
- Protein GOLVEN 5
- Protein GOLVEN 2
- Protein GOLVEN 4
- Phytosulfokine
Sequence:
MKKTSLKLMTLVLGFCFVIYLLQGPRGGSRNGDLLIARKLISLEPIETKNAARSLKDSISTDLEEEVDRLMEHEYPSPVKPRKRTPVHNGVRNRH
Protein: (R)-specific enoyl-CoA hydratase (EC 4.2.1.119) ((R)-specific trans-2,3-enoylacyl-CoA hydratase) (Q2RQ36)
Organism: Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)
Function: Catalyzes the hydration of trans-2-enoyl-CoAs with a chain-length of 4-6 carbon atoms, forming the corresponding (3R)-3-hydroxyacyl-CoAs, which can then be utilized for the production of polyhydroxyalkanoates (PHA) polymers. Cannot use trans-2,3-octenoyl-CoA as substrate.
Interaction partners:
- 3-hydroxyisobutyryl-CoA hydrolase
- enoyl-CoA hydratase
- 3-oxoacyl-[acyl-carrier-protein] reductase
- Poly
- Alpha/beta hydrolase fold
- Poly
- Crotonyl-CoA reductase
- Biotin/lipoyl attachment
- Uncharacterized protein
- oxaloacetate decarboxylase
Sequence:
MSADDLILHYFEDIKEGQSASLAKTISESDIYLFAGLSMDTNPAHVNEDYAQTTVFKTRIAHGMLSAGFISAVLGTRLPGPGAIYVNQSLKFKAPVRIGDTVTATVTVTGLVPEKKFVTFRTTCTVAGKVVIEGEATVMVPARG
Protein: Disease resistance protein (TIR-NBS-LRR class) (F4HR54)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MMKTGAVVSNPRSRVKWDAFLSFQRDTSHNFTDRLYEALVKEELRVWNDDLERVDHDHDHELRPSLVEAIEDSVAFVVVLSPNYANSHLRLEELAKLCDLKCLMVPIFYKVEPREVKEQNGPFEKDFEEHSKRFGEEKIQRWKGAMTTVGNISGFICGYEIQLEMETGVVPNRLKYSVFLSFRGFDTRTNFCERLYIALNEKQNVRVFRDNEGMEKGDKIDPSLFEAIEDSAASVIILSTNYANSSWCLDELALLCDLRSSLKRPMIPIFYGVNPEDVRKQSGEFRKDFEEKAKSFDEETIQRWKRAMNLVGNIPGYVCTAKTVGDDNEGINREKVDDMIDLVVKKVVAAVRNRPEIVADYTVGLESPIKDLMKLFNTESSSGIQVMGLYGMGGIGKTTLAKAFYNKIIVNFNRHRVFIESVRGKSSDQDGLVNLQKTLIKELFRLVPEIEDVSIGLEKIKENVHEKKIIVVLDDVDHIDQVNALVGETSWYGEGSLIVITTRDSEILSKLSVNQQYEVKCLTEPQALKLFSFYSLRKEKPPTQGLLELSKKIAEVTGLLPLAVKVFGSHFYDKDENEWQVELEKLKTQQDKLHGVLALSFKSLDEEEKKIFLDIACLFLKMDITKEEVVDILKGCGLNAEAALRVLIQKSLLTILTDDTLWMHDQIRDMGRQMVHKESSDDPEMRSRLWDRGEIMNVLDYMKGTSSIRGIVLDFNKKFARDHTADEIFSSNLRNNPGIYSVFNYLKNKLVRFPAEEKPKRSEITIPVESFAPMKKLRLLQINNVELEGDLKLLPSELKWIQWKGFPLENLPPDILSRQLGVLDLSESGVRRVKTLPRKRGDENLKVVNLRGCHGLEAIPDLSNHNALEKLVLERCNLLVKVPRSVGNLGKLLQLDLRRCSSLSEFLGDVSGLKCLEKFFLSGCSNLSVLPENIGSMPCLKELLLDGTAISNLPYSIFRLQKLEKLSLMGCRSIEELPSCVGYLTSLEDLYLDDTALRNLPSSIGDLKNLQKLHLMRCTSLSTIPETINKLMSLKELFINGSAVEELPIETGSLLCLTDLSAGDCKFLKQVPSSIGGLNSLLQLQLDSTPIEALPEEIGDLHFIRQLDLRNCKSLKALPKTIGKMDTLYSLNLVGSNIEELPEEFGKLENLVELRMNNCKMLKRLPKSFGDLKSLHRLYMQETLVAELPESFGNLSNLMVLEMLKKPLFRISESNVPGTSEEPRFVEVPNSFSKLLKLEELDACSWRISGKIPDDLEKLSCLMKLNLGNNYFHSLPSSLVKLSNLQELSLRDCRELKRLPPLPCKLEQLNLANCFSLESVSDLSELTILTDLNLTNCAKVVDIPGLEHLTALKRLYMTGCNSNYSLAVKKRLSKASLKMMRNLSLPGNRVPDWFSQGPVTFSAQPNRELRGVIIAVVVALNDETEDDDYQLPDVMEVQAQIHKLDHHKCTNTLHLSGVPRTNNDQLHICRYSAFHPLVTMLKDGYTIQVIKRNPPIKQGVELKMHGIHLVYEGDDDLEGRENTLPEAQQTVSQKLANFFSSFEEGEASAKGDSTVA
Protein: U6 snRNA-associated Sm-like protein LSm6 (P62312)
Organism: Homo sapiens (Human)
Function: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12515382}. Nucleus {ECO:0000269|PubMed:10523320, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28781166}.
Interaction partners:
- Small nuclear ribonucleoprotein G
- U6 snRNA-associated Sm-like protein LSm7
- U4/U6 small nuclear ribonucleoprotein Prp3
- U6 snRNA-associated Sm-like protein LSm1
- U2 small nuclear ribonucleoprotein A'
- U6 snRNA-associated Sm-like protein LSm4
- U6 snRNA-associated Sm-like protein LSm5
- U6 snRNA-associated Sm-like protein LSm2
- U6 snRNA-associated Sm-like protein LSm8
- Small nuclear ribonucleoprotein Sm D2
Sequence:
MSLRKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDAFIRGNNVLYISTQKRRM
Protein: ATP-dependent DNA helicase CHL1 (EC 5.6.2.3) (Chromosome loss protein 1) (Chromosome transmission fidelity protein 1) (DNA 5'-3' helicase CHL1) (P22516)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.
Subcellular location: Nucleus {ECO:0000269|PubMed:10931920, ECO:0000269|PubMed:15020404, ECO:0000269|PubMed:15226378}.
Interaction partners:
- Pre-tRNA-processing protein PTA1
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Chromosome transmission fidelity protein 18
- N-acetyltransferase ECO1
- DNA polymerase alpha-binding protein
- Chromosome transmission fidelity protein 8
- Sister chromatid cohesion protein DCC1
- Mediator of replication checkpoint protein 1
- Large ribosomal subunit protein uL15
- RNA polymerase II transcription factor B subunit 3
Sequence:
MDKKEYSETFYHPYKPYDIQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADIFTRMETNIKTNEDDSENLSDDEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEINTTSCKQLKTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLEEQDFIPRPYESDSENNDTSKSTRGGRISDKDYKLSELNSQIITLLDKIDGKVSRDPNNGDRFDVTNQNPVKIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLRHSKEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEVVTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKNFKKIGQEIDPNDMFTGSNIDTLNIHKLLRYIKVSKIAYKIDTYNQALKEEESSKNENPIKETHKKSVSSQPLLFKVSQFLYCLTNLTSEGQFFFEKNYSIKYMLLEPSKPFESILNQAKCVVLAGGTMEPMSEFLSNLLPEVPSEDITTLSCNHVIPKENLQTYITNQPELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAKDGDDILSGYSDSVAEGRGSLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGGTEEEASRATKEFMENICMKAVNQSVGRAIRHANDYANIYLLDVRYNRPNFRKKLSRWVQDSINSEHTTHQVISSTRKFFSMRSLNSR
Protein: Solute carrier organic anion transporter family member 1A3 (OAT-K2) (Sodium-independent organic anion transporter K1) (OAT-K1) (Solute carrier family 21 member 4) (rOAT-K) (P70502)
Organism: Rattus norvegicus (Rat)
Function: Mediates the Na(+)-independent transport of organic anions such as methotrexate, taurocholate, folate and prostaglandin E2. May contribute to renal secretion and/or reabsorption of hydrophobic anionic compounds. Mediates renal clearance of methotrexate from the blood.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Solute carrier family 7 member 13
- Solute carrier family 22 member 6
Sequence:
MGDLEKGAATHGAGCFAKIKVFLMALTCAYVSKSLSGTFMSSMLTQIERQFGIPTAIVGFINGSFEIGNLLLIIFVSYFGMKLHRPIVIGVGCAVMGLGCFIISLPHFLMGRYEYETTILPTSNLSSNSFLCMENQTQTLNPAQDPAECVKEVKSLMWIYVLVGNIIRGIGETPIMPLGVSYIENFAKSENSPLYIGILETGKMIGPIFGLLLGSFCASIYVDTGSVNTDDLTITPTDIRWVGAWWIGFLVCAGVNILISIPFFFFPKTLPKEGLQENVDGTENAKEESTEKRPRKKNRGITKDFFPFLKSPVLQPDLHAVHPYKVLQVNAFNIYFSFLPKYLENQYGKSTAEVIFLMGVYNLPAICIGYLIAGFMMKKFKITVKTAAFLAFCLSLSEYSFGFCNFLITCDNVPVAGLTNSYERDQKPLYLENNVLADCNTRCSCLTKTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVFHNCSCIQSPGNSSAVLGLCNKGPECTNKLQYLLILSGFLSILYSFAAIPGYMVFLRCIKSEEKSLGIGIHAFCIRVFAGIPAPIYFGALIDRTCLHWGTQKCGAPGACRMYDINSFRRIYLGMSAALRGSSYLPAFVIVILTRKFSLPGKINSSEMEIAEMKLTEKESQCTDVHRNPKFKNDGELKTKL
Protein: Calcium and calcium/calmodulin-dependent serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (CCaMK DMI3) (MtCCaMK) (Protein DOES NOT MAKE INFECTIONS 3) (Q6RET7)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: During nodulation, plays a central role in bacterial infection and contributes to nodule organogenesis. Protein kinase that recognizes the calcium spiking induced by Nod factors and translates this signal to components controlling nodulation and mycorrhizal infection responses. May phosphorylate the NSP1 protein. Required in epidermal and cortical cells to promote infection thread (IT) formation in root hairs.
Subcellular location: Nucleus {ECO:0000269|PubMed:17722695}.
Interaction partners:
- Protein CYCLOPS
- Serine/threonine receptor-like kinase NFP
- Protein VAPYRIN
- Nuclear transcription factor Y subunit
- Protein NODULATION SIGNALING PATHWAY 1
- Protein NODULATION SIGNALING PATHWAY 2
- Early nodulin-11
- Glycerol-3-phosphate acyltransferase RAM2
- Ethylene-responsive transcription factor ERN1
- Nod-factor receptor 5
Sequence:
MGYGTRKLSDEYEVSEILGRGGFSVVRKGTKKSSIEEEKSQSQVAIKTLRRLGASNNPSGLPRKKDIGEKSTIGFPTMRQVSVSDTLLTNEILVMRRIVENVSPHPNVIDLYDVYEDTNGVHLVLELCSGGELFDRIVAQDKYSETEAATVVHQIASGLEAVHRANIVHRDLKPENCLFLDVRKDSPLKIMDFGLSSVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYILLSGYPPFIAQNNRQKQQMIMNGNFSFYEKTWKGISQPAKNLISSLLTVDPSKRPSALELLSDPWVKGEKAKDVQMDPEIVSRLQSFNARRKLRAAAIASVWSSTIFLRTKKLKSLVGSYDLKEEEIENLRMHFKKICADRDNATLSEFEEVLKAMNMLSLIPFASRIFDLFDNNRDGTVDMREILCGFSSLKNSKGEDALRLCFQMYDTDRSGCISKEEVASMLRALPYDCLPTDITEPGKLDEIFDLMDANNDGKVTFDEFKAAMQRDSSLQDVVLSSIRP
Protein: Calpain-6 (O35646)
Organism: Mus musculus (Mouse)
Function: Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17210638, ECO:0000269|PubMed:20814968}.
Interaction partners:
- Calpain small subunit 1
- Calpain small subunit 2
Sequence:
MGPPLKLFKNQKYQELKQECMKDGRLFCDPTFLPENDSLFFNRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKDQEWDPRKPEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLICCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIIQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL
Protein: Protein STRUBBELIG (Leucine-rich repeat receptor kinase-like protein SUB) (Protein SCRAMBLED) (Q8RWZ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates the expression of transcription factors that define the cell fates. Acts in a non-cell-autonomous fashion, functions in a radial inside-out signaling process, and mediates cell morphogenesis and cell fate across clonally distinct cell layers in floral primordia, developing ovules, and root meristems. Seems to be required for the regulation of cell shape and the orientation of the mitotic division plane. Involved in root hair specification, in the formation of the outer integument and the shape of organs such as carpels and petals and is necessary for the shape and height of the stem. Non-functional SUB proteins are retained in the endoplasmic reticulum and degraded by endoplasmic reticulum-associated degradation (ERAD).
Subcellular location: Cell membrane {ECO:0000269|PubMed:25256344}; Single-pass membrane protein {ECO:0000305}. Cell junction, plasmodesma {ECO:0000269|PubMed:25256344}.
Interaction partners:
- Protein QUIRKY
- Protein OS-9 homolog
- FT-interacting protein 1
- C-terminal binding protein AN
- Transcription factor WER
- FT-interacting protein 3
Sequence:
MSFTRWEVFFGLSVLALTMPFSAGVTNLRDVSAINNLYITLGAPSLHHWLAFGGDPCGEKWQGVVCDSSNITEIRIPGMKVGGGLSDTLADFSSIQVMDFSSNHISGTIPQALPSSIRNLSLSSNRFTGNIPFTLSFLSDLSELSLGSNLLSGEIPDYFQQLSKLTKLDLSSNILEGHLPSSMGDLASLKILYLQDNKLTGTLDVIEDLFLTDLNVENNLFSGPIPPNLLKIPNFKKDGTPFNTSIITPPPPPVVDPPPATHRAPPVPRIPPVSGVPPAPFAPFAPLQPQQHPPPSPPLVWSPPSSDNGGGDPWNSVSGQPTLQISPPSGSGSGKFWSTQRIILVVSSVAIIVLVSGLCVTLWRCCRSKIYNRYYSGARKDLQRPYFNKPPSQPTPTMGKVSREPMVKPFDGYGAGDRKYGYPMPQRAEESRRAMPPTSYYNKDVNTPQKPLQQPPRQFQSNDTASKRAAHFPPGLNSSSSATVFTIASLQQYTNNFSEENIIGEGSIGNVYRAELRHGKFLAVKKLSNTINRTQSDGEFLNLVSNVLKLKRGHILELLGYCNEFGQRLLVYEYCPNGSLQDALHLDRKLHKKLTWNVRINIALGASKALQFLHEVCQPPVVHQNFKSSKVLLDGKLSVRVADSGLAYMLPPRPTSQMAGYAAPEVEYGSYTCQSDVFSLGVVMLELLTGRRPFDRTRPRGHQTLAQWAIPRLHDIDALTRMVDPSLHGAYPMKSLSRFADIISRSLQMEPGFRPPISEIVQDLQHMI
Protein: Inhibitor of cysteine peptidase (Q57YP6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cysteine peptidase
- Cysteine peptidase
- Cysteine peptidase
- Cysteine peptidase
- Cysteine peptidase
- CSC1/OSCA1-like 7TM region domain-containing protein
Sequence:
MSHNLFTEEDNNKTIRMVIGETFTIELKSNPTTGYTWLRSGLAGTELSDCTFAIQSKFNNRAPHDNHKNHRRLLVGAGGTMVLEVKALKPGKHTLSLAYGRPWVGFNAAAKRYNIHVEATA
Protein: Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4-like protein) (Nucleolar complex-associated protein 4-like protein) (Q9BVI4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus membrane {ECO:0000269|PubMed:12429849}; Multi-pass membrane protein {ECO:0000269|PubMed:12429849}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
Interaction partners:
- U3 small nucleolar ribonucleoprotein protein IMP4
- Ribosomal RNA small subunit methyltransferase NEP1
- Nucleolar protein 14
- U3 small nucleolar RNA-associated protein 18 homolog
- WD repeat-containing protein 3
- WD repeat-containing protein 43
- Nucleolar protein 10
- Small subunit processome component 20 homolog
- WD repeat-containing protein 36
- Transducin beta-like protein 3
Sequence:
MEREPGAAGVRRALGRRLEAVLASRSEANAVFDILAVLQSEDQEEIQEAVRTCSRLFGALLERGELFVGQLPSEEMVMTGSQGATRKYKVWMRHRYHSCCNRLGELLGHPSFQVKELALSALLKFVQLEGAHPLEKSKWEGNYLFPRELFKLVVGGLLSPEEDQSLLLSQFREYLDYDDTRYHTMQAAVDAVARVTGQHPEVPPAFWNNAFTLLSAVSLPRREPTVSSFYVKRAELWDTWKVAHLKEHRRVFQAMWLSFLKHKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDLGGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGPELDADPYDPGEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPEVSIAPLLELTAYEIFERDLKKKGPEPVPLEFIPAQGLLGRPGELCAQHFTLS
Protein: Transporter, putative (Q38DC2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MQQKSDAVTPLPLKQMFPLALVLLNESLCSSILLPYVGYLVSFFEKCPPEEAGYMSGVVLGSFMLGQFTSGKMWGWMSDYYGRKPTLALGLIIGGLMVLCFGFSGNIWVCIIFRFFHGLSNGNLLVAKTVLADILDRTNEAQGFAMVSFTYGFGILIGPAMGGLLYDPANSNMFRWAGFRKDGVFARYPGLMPAVACFFYAIFALVICLVFLAETNPHARPLPGWILALLPSSLRLRATHEVVPNNENIEAVVVEPEPDYFFNGLPDESDILGENHGTATWEKSQQLSFRKDGTNEEAKQHKEAAPNGTNGRVDSHLEVDREASAPALRGADEISVATSQEKEPFGYRDSFVNPNTRCVLVTYMLICCGDVAFSEIFSLWAIAGTSHGGLGYQASAVGTLLLTNSFPCLLSNVTLHLACRVITNKLVLWRISVMIISVVVGLMPFVTYAVGGAQIPLLLMCTFARQWFSSWAFGLITIFTARVAPPLHTGTMYGIAQSCGSIVRCVIPFAITPLFAWSISGHKPIPFNSVLTFLISSVMFISACVGSLGLKVEDENELQNEQQLETNYVVVMDCEFDDGDARGGIFTGIKG
Protein: Protein PHLOEM PROTEIN 2-LIKE A1 (AtPP2-A1) (O81865)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein PHLOEM PROTEIN 2-LIKE A9
- Protein SIEVE ELEMENT OCCLUSION A
- Protein SIEVE ELEMENT OCCLUSION C
- Protein SIEVE ELEMENT OCCLUSION B
- GDSL esterase/lipase At1g09390
- GDSL esterase/lipase At5g62930
- At1g62510
- GDSL esterase/lipase LIP-4
- GDSL esterase/lipase At5g14450
- Serine/threonine-protein phosphatase PP1 isozyme 1
Sequence:
MSKKHCSELLPNKMFRNQDSKYLIPVQKEAPPVTTLPMKASTVKSPHNCEAILRDADPPISLSSVNLSEQLRSGVFLKPKKQIKYWVDERNSNCFMLFAKNLSITWSDDVNYWTWFTEKESPNENVEAVGLKNVCWLDITGKFDTRNLTPGIVYEVVFKVKLEDPAYGWDTPVNLKLVLPNGKEKPQEKKVSLRELPRYKWVDVRVGEFVPEKSAAGEITFSMYEHAAGVWKKGLSLKGVAIRPKQ
Protein: Transcription initiation factor IIE subunit beta (TFIIE-beta) (P79011)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription initiation factor IIE subunit alpha
- Transcription initiation factor IIF subunit beta
- Transcription initiation factor IIF subunit alpha
- RNA polymerase II transcription factor B subunit 3
- General transcription and DNA repair factor IIH subunit ssl1
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH subunit tfb4
- Serine/threonine-protein kinase crk1
- General transcription and DNA repair factor IIH subunit tfb1
Sequence:
MSSLSDQLSSFKKKVANQPIYAKPQPRQPASPTPTAYLNSNDGHSSAASSPGSYSLKKKRSKTSLVYSQPADSGVGTHYLSQLHYAVEYLKERNEPKTAEEIASYLSTPLTPMLLNLLKKNNRIYYDERNETFTFKPLHNIRSGAGLLAYLDSQKTHVGMSIKELRDGWPNVTVELEELEKQGEVLLLRTRKDGVPKMVWRNDKSCDCHVDKEFQQVWHEIPIPPTLDLASELGKYGLKPTSVDPSTVKRAGHNQTPKQKKPKTRRGKITNTHLNILRDYSSMKP
Protein: Translation initiation factor eIF2B subunit gamma (eIF2B GDP-GTP exchange factor subunit gamma) (Q8MSR4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}.
Interaction partners:
Sequence:
MAEFQAVVFAAGRGTRLPEVLGDAPKCLLPVGPYPLIWYPLNLLQQHNFSEVIVVVLEQEKLEIQSALENTPLKLRLDYATIPSDGDFGTADSLRYIYDKIKSDFLVVSCDLVSNVSLYPLINKFREHDAALAMLLFPSGFESDVVMPGPKSKHKPERDLIGIHAATQRLAFVSAASDCEETLNIQRHLLKNRGRLDVYSRLVDAHVYVLKKWVIDYLRRKENISTFKGEFLPHLIKKQHSKRPPKTVQDTTSEVGVVTKNEDHVLHYVGHTILDQKITQTSLFNQSLSQSPYHGDIVRCYGIQAPRDAIGVRVNNTLSFLAINRKLASIWNNLCGEKHPLISPGAVVKSTQTKEIIAADNAKLSEKTSLNFSVFGPNCIISPKNIVANSLIMSNAIVEEGCNIDNCIIGHRAQVKSGSVLKNCIIGPNYVVEEGTHSQAVHLSNADQFMEIDIQ
Protein: RING/U-box superfamily protein (F4JWA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable phospholipid-transporting ATPase 12
- Phospholipid-transporting ATPase 3
- Cyclase-associated protein 1
- Probable E3 ubiquitin-protein ligase ARI8
Sequence:
MTSIQPLLQKSESRDDVRAEFERGLEEFMRGHLDECISFGSCSSVHNPEDEDNEDDQLVRRRRRSELEGDNLAESSAARRRQSQILSRWAARQAQEMITTIERRNRESELIALAGLQTVSMLDSSFLRESQSQSPSSRRQGAASERPNTQASGILQMWRELEDEHVLNRARERVRERLRQQRSVESNTNLSSSIASESQLSENNGSLRDSSESENDFGSWSHDRNEHGDNNNTSSREQSPDLGDGERERVRHIARGWMDSRINDHSSNVRQRDDNRRPEWLGDTERERVRIIREWMQMTSQQRGGARATPREDQRSTSEADRNHDAAPQVDRVRVGLAVNHEEGQPPHVRRDLRRVRGRQALLDLLMRAERERQRELQGLLEHRAVSDFAHRNRIQSLLRGRFLRNERPTVPERTPSMASRELLQLRERQTVSGLREGFHNGRENIVHENTSNTDNDNSNTSTNALAIAITAGNSQRVTDESSTSSRQGNDSPILPDNSESNLANADRDWEEDTNQRRIWQENVPVDERPNLEQTTLTQFDGYDNTDINRDETSVSDMHREASGFADDEYRTQEAHGVWHENSSRQSDGNWPGTRSEALRSRRVVQLRRLNRFHPPEDDNVYSMELRELLSRRSVSNLLHSGFRESLDQLIQSYAERRGHTHVDWDLHANLQTAIPDSPERDTDHQVFVRNDNQLNGINGSQLLPTPPAPPPQPIWHQDLHHTSWSRHSMHRSEIEWEVMNDLRGDVARLQQGMSQMQRMLEACMDMQLELQRSVRQEVSAALNRSAGDQGMSAETSEDGSRWSHVSKGTCCVCCDNHIDALLYRCGHMCTCSKCANELVRNGGKCPLCRAPIIEVIRAYSIL
Protein: Protein PET117 homolog, mitochondrial (Q6UWS5)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:22356826}.
Interaction partners:
- Heme A synthase COX15
- Probable thioesterase PNKD
- Protein PET100 homolog
- Cytochrome c oxidase assembly factor 5
- Cytochrome c oxidase copper chaperone
- Cytochrome c oxidase assembly factor 6 homolog
- Protoheme IX farnesyltransferase, mitochondrial
Sequence:
MSRSSKVVLGLSVLLTAATVAGVHVKQQWDQQRLRDGVIRDIERQIRKKENIRLLGEQIILTEQLEAEREKMLLAKGSQKS