wanglab/gogpt-training-data huggingface dataset:
Protein: Nidogen-1 (NID-1) (Entactin) (P08460)
Organism: Rattus norvegicus (Rat)
Function: Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane.
Interaction partners:
- Basement membrane-specific heparan sulfate proteoglycan core protein
- Laminin subunit gamma-1
- Aa1018
- Agrin
- CD44 antigen
- Fibulin-2
- Fibronectin
- Decorin
- Laminin subunit beta-1
- Collagen type IV alpha 1 chain
Sequence:
EFHPGTFPPSFGSVAPFLADLDTTDGLGNVYYREDLSPFIIQMAAEYVQRGFPEVSFQPTSVVVVTWESMAPYGGPSGSLVEEGKRNTFQAVLASSNSSSYAIFLYPDDGLQFFTTFSKKDENQVPAVVGFSKGLEGFLWKSNGAYNIFANDRESIENLAKSSNAGHQGVWVFEIGSPATAKGVVPADVNLDVDDDGADYEDEDYDLQTSHLGLEDVATQPFPSHSPRRGYPDPHNVPRTLAPSYEATERPHGIPTERTKSFQLPVERFPQKHPQVIDVDEVEETGVVFSYNTGSQQTCANNRHQCSVHAECRDYATGFCCRCV
Protein: Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1) (O70310)
Organism: Mus musculus (Mouse)
Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' (By similarity). Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle (By similarity). Required for normal embryogenesis.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P30419}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P30419}. Membrane {ECO:0000250|UniProtKB:P30419}; Peripheral membrane protein {ECO:0000250|UniProtKB:P30419}. Note=Copurifies with ribosomes. {ECO:0000250|UniProtKB:P30419}.
Interaction partners:
- Dephospho-CoA kinase domain-containing protein
- Guanine nucleotide-binding protein G
- BH3-interacting domain death agonist
- Acyl-CoA-binding domain-containing protein 6
Sequence:
MADESETAVKLPAPSLPLMMEGNGNGHEHCSDCENEEDNSHNRSGLSPANDTGAKKKKKKQKKKKEKGSDMESTQDQPVKMTSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMEKKDIPVVHQLLSRYLKQFHLTPVMNQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
Protein: Ankyrin repeat domain 13A (S4R3U2)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
Sequence:
XPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEESVSQNVEGTQADSASHITNFEVDQSVFEIPESYYVQDNGRNVHLQDEDYEIMQFAIQQILQLSLTDK
Protein: Odorant receptor Or2 (AgOr2) (Q8WTE6)
Organism: Anopheles gambiae (African malaria mosquito)
Function: Odorant receptor which plays a critical role in the anthropophilic host-seeking behavior; establishes the host preference to transmit malaria.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Odorant receptor coreceptor
- AGAP012472-PA
Sequence:
MLIEECPIIGVNVRVWLFWSYLRRPRLSRFLVGCIPVAVLNVFQFLKLYSSWGDMSELIINGYFTVLYFNLVLRTSFLVINRRKFETFFEGVAAEYALLEKNDDIRPVLERYTRRGRMLSISNLWLGAFISACFVTYPLFVPGRGLPYGVTIPGVDVLATPTYQVVFVLQVYLTFPACCMYIPFTSFYATCTLFALVQIAALKQRLGRLGRHSGTMASTGHSAGTLFAELKECLKYHKQIIQYVHDLNSLVTHLCLLEFLSFGMMLCALLFLLSISNQLAQMIMIGSYIFMILSQMFAFYWHANEVLEQSLGIGDAIYNGAWPDFEEPIRKRLILIIARAQRPMVIKVGNVYPMTLEMFQKLLNVSYSYFTLLRRVYN
Protein: Uncharacterized protein 1 (P86731)
Organism: Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone)
Subcellular location: Secreted {ECO:0000269|PubMed:21050442}.
Interaction partners:
Sequence:
MVLHVITALLSIGLCYGMPPSGTTAAPTAYNGAAAQESLIPQQAHHARASLFPQQQRNPSYQTMGSYGSSLFDPSVFPVAHAPASQAGGLLGRAVARTSGGQANAGASSQNLMRSIMQNTMTGRLMGLDNQEIAHLNSVRTLGVGHATIHRLMKIDQIPSYNYYLALKNKPAQFSKAQNYLMTLNRMENHATDSQLEAMGARMLMQRNMDPDLARMVQLDAARGVYGDRLQRVLLGGSQMSLLG
Protein: Cathepsin O (EC 3.4.22.42) (P43234)
Organism: Homo sapiens (Human)
Function: Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover.
Subcellular location: Lysosome.
Interaction partners:
- Apoptosis regulator Bcl-2
- Bcl-2-like protein 1
- BH3-interacting domain death agonist
Sequence:
MDVRALPWLPWLLWLLCRGGGDADSRAPFTPTWPRSREREAAAFRESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV
Protein: Myc target protein 1 (Myc target in myeloid cells protein 1) (Q8N699)
Organism: Homo sapiens (Human)
Function: May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:12673574}. Note=Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells.
Interaction partners:
Sequence:
MRTQVYEGLCKNYFSLAVLQRDRIKLLFFDILVFLSVFLLFLLFLVDIMANNTTSLGSPWPENFWEDLIMSFTVSMAIGLVLGGFIWAVFICLSRRRRASAPISQWSSSRRSRSSYTHGLNRTGFYRHSGCERRSNLSLASLTFQRQASLEQANSFPRKSSFRASTFHPFLQCPPLPVETESQLVTLPSSNISPTISTSHSLSRPDYWSSNSLRVGLSTPPPPAYESIIKAFPDS
Protein: Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB) (P40018)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q10163}. Cytoplasm {ECO:0000250|UniProtKB:Q10163}.
Interaction partners:
- U1 small nuclear ribonucleoprotein 70 kDa homolog
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor PRP46
- LSM complex subunit LSM2
- Pre-mRNA-splicing factor CLF1
- Pre-mRNA-splicing factor SNT309
- Pre-mRNA-processing factor 39
- Pre-mRNA-splicing factor CWC2
- Pre-mRNA-splicing factor SYF1
- Protein HSH49
Sequence:
MSKIQVAHSSRLANLIDYKLRVLTQDGRVYIGQLMAFDKHMNLVLNECIEERVPKTQLDKLRPRKDSKDGTTLNIKVEKRVLGLTILRGEQILSTVVEDKPLLSKKERLVRDKKEKKQAQKQTKLRKEKEKKPGKIAKPNTANAKHTSSNSREIAQPSSSRYNGGNDNIGANRSRFNNEAPPQTRKFQPPPGFKRK
Protein: Large ribosomal subunit protein eL22 (60S ribosomal protein L22) (Q383R3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 60S ribosomal protein L4
- 60S ribosomal protein L27, putative
- 60S ribosomal protein L2, putative
- Large ribosomal subunit protein uL5
- 60S ribosomal protein L29
- 60S ribosomal protein L39, putative
- 60S ribosomal protein L19, putative
- 60S ribosomal protein L35A, putative
- 60S ribosomal subunit protein L31, putative
- 60S ribosomal protein L7a
Sequence:
MVAVRAKVGSRGFTRQRQLAKGKKVFKIDCSIPASDGIFSDDILSNFQQYFQDNVKLNGRKGKLTSKVRVNMRENTLSITTTMAYRKKYFKYLTKKFLKKKDLRDWIRILAKGKDTYQLKYFNIQDQEEA
Protein: Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta) (P83916)
Organism: Homo sapiens (Human)
Function: Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Subcellular location: Nucleus {ECO:0000269|PubMed:10460410, ECO:0000269|PubMed:28977666, ECO:0000269|PubMed:9169582}. Note=Unassociated with chromosomes during mitosis.
Interaction partners:
- Histone H3.2
- Histone H3.1
- Histone H3-7
- Histone H3.1t
- Histone H3.3
- Histone H3.3C
- E3 ubiquitin-protein ligase RING1
- Polycomb complex protein BMI-1
- Polycomb complex protein BMI-1
- Histone-lysine N-methyltransferase SUV39H1
Sequence:
MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
Protein: Uracil-regulated protein 1 (EC 3.5.4.-) (Q9US41)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Protein urg3
- Putative uracil phosphoribosyltransferase urg2
- 6,7-dimethyl-8-ribityllumazine synthase
- Riboflavin synthase
- Uracil phosphoribosyltransferase 2
Sequence:
MLATEQSRPAECNGAHAHEKTEEVKKPLYSRPVVLTTYPSQSRIDPFPMNWGAATAEERGPITVARSIETLPHRNAVGAHGGSYSVYNALAVAGGFLPPDHRPNFELTEPTFDFPELDSWHDPKKIVAMDPYGHLTPSVFKKYLDEGYDVRPTIAITRAHLQVTEIQRSVENGSLPIDGKIVLNEKGDIAVTKVAVEPVWYLPGVAERFGVDEVTLRRALFEQMGGAYPELITRPDIKVFLPPIGGLTAYIFGPPEYLSDTSKSLAVRVHDECNGSDVFQSDICTCRPYLTFGIEEAAKEAQNGGAGLVVYFRKEGRALGEVVKYLVYNKRKRTGDSAENYFKRTEELAGVRDMRFQALMPDILHWFGIKKIDRMLSMSNMKHDAIVGQGIKILNRITIPDDLIPEDSQVEIDAKIQSGYFSEKKVTEDDLSCVHGRHW
Protein: Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Threonyl dipeptidase) (J3QKT2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAALTTLFKYIDENQDRYIKKLAKWVAIQSVSAWPEKRGEIRRMMEVAAADVKQLGGSVELVDIGKQKLPDGSEIPLPPILLGRLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVERDGKLYGRGSTDDKGPVAGWINALEAYQKTGQEIPVNVRFCLEGMEESGSEGLDELIFARKDTFFKDVDYVCISDNYWLGKKKPCITYGLRGICYFFIEVECSNKDLHSGVYGGSVHEAMTDLILLMGS
Protein: Achaete-scute complex protein T8 (Protein asense) (P09775)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the determination of the neuronal precursors of optic lobes in the central nervous system.
Interaction partners:
- Worniu
- Protein deadpan
- RE18076p
- Fez family zinc finger protein erm
- Inscuteable
- Protein atonal
- Achaete-scute complex protein T4
- Enhancer of split mgamma protein
- Protein escargot
Sequence:
MAALSFSPSPPPKENPKENPNPGIKTTLKPFGKITVHNVLSESGANALQQHIANQNTIIRKIRDFGMLGAVQSAAASTTNTTPISSQRKRPLGESQKQNRHNQQNQQLSKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTPGRKGLPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFPPLNSQGNSSGSGDDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQTVQQTLSEDMLNPPQASDLLPSLTTLNGLQYIRIPGTNTYQLLTTDLLGDLSHEQKLEETAASGQLSRSPVPQKVVRSPCSSPVSPVASTELLLQTQTCATPLQQQVIKQEYVSTNISSSSNAQTSPQQQQQVQNLGSSPILPAFYDQEPVSFYDNVVLPGFKKEFSDILQQDQPNNTTAGCLSDESMIDAIDWWEAHAPKSNGACTNLSV
Protein: Opacity protein opA56 (Q04879)
Organism: Neisseria gonorrhoeae
Function: Implicated in a number of adherence functions. OPA proteins are implicated in pathogenesis and are subject to phase variation.
Subcellular location: Cell outer membrane.
Interaction partners:
Sequence:
AGEDHGRGPYVQADLAYAYEHITHDYPEQTGTKKDKISTVSDYFRNVRTHSIHPRVSVGYDFGGWRIAADYARYRKWNDDKYSVDIKELENKNQNKRDLKTENQENGTFHAVSSLGLSAVYDFKLNDKFKPYIGARVAYGHVRHSIDSTKKTTKFLTSSYGGLNPTVYTEENTQNAHHQSNSIRRVGLGVIAGVGFDITPKLTLDTGYRYHYWGRLENTRFKTHEASLGVRYRF
Protein: Transcriptional regulatory protein AlgQ (Alginate regulatory protein AlgR2) (P15275)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process.
Interaction partners:
- RNA polymerase sigma factor RpoD
- Transcriptional regulatory protein AlgP
- UPF0301 protein AlgH
- GDP-mannose 6-dehydrogenase
- Positive alginate biosynthesis regulatory protein
- RNA polymerase sigma factor RpoS
- Nucleoside diphosphate kinase
- Yip1 domain-containing protein
- Yip1 domain-containing protein
- RNA polymerase sigma-H factor
Sequence:
MLESCRNAQERWGGVHQLIDRWLHERQQLVQAFDALSGIQAPAPNAEELQHFCQLLLDYVSAGHFEVYEQLTAEGKAFGDQRGLELAKQIFPRLEAITESALNFNDRCDNGDCREGACLIAELKVLRQQLHERFELEDCLIEVLHNAHSQSGAEGSAVPV
Protein: Monothiol glutaredoxin-7 (P38068)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Glutaredoxin-8
- Monothiol glutaredoxin-3
- Monothiol glutaredoxin-5
- Low molecular weight phosphotyrosine protein phosphatase
- Glutaredoxin-1
Sequence:
MAIVINKRNVRVLVITNLLLIVVFFVLRNSNASVNESITTHHPDSLVTFDNSGNAPGTHQSVHDTVNTQDKEAEEVDKNSGDAEFDAAAEYNKIMEQSPMIVFSKTGCPYSKKLKALLTNSYTFSPSYYVVELDRHEHTKELQDQIEKVTGRRTVPNVIIGGTSRGGYTEIAELHKNDELLDSFKKWSDGAFTVKANSQSESA
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Q5LJB0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSLGWLERPPALSRAAGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEPMDTDQGNSMLSAIQSEVAKNQ
Protein: Mitochondrial import receptor subunit TOM34 (hTom34) (Translocase of outer membrane 34 kDa subunit) (Q15785)
Organism: Homo sapiens (Human)
Function: Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10101285}. Mitochondrion outer membrane {ECO:0000269|PubMed:10101285}; Peripheral membrane protein {ECO:0000269|PubMed:10101285}; Cytoplasmic side {ECO:0000269|PubMed:10101285}.
Interaction partners:
- DnaJ homolog subfamily C member 7
- Heat shock protein HSP 90-beta
- Heat shock protein HSP 90-alpha
- Heat shock 70 kDa protein 4
Sequence:
MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH
Protein: Thymosin beta-10 (P63312)
Organism: Rattus norvegicus (Rat)
Function: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
Sequence:
MADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
Protein: Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1) (Q0VGK0)
Organism: Rattus norvegicus (Rat)
Function: Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.
Subcellular location: Cytoplasmic vesicle, autophagosome {ECO:0000250|UniProtKB:Q9H0R8}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9H0R8}; Lipid-anchor {ECO:0000250|UniProtKB:Q9H0R8}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16650615}. Endoplasmic reticulum {ECO:0000269|PubMed:16650615}. Golgi apparatus {ECO:0000269|PubMed:16650615}.
Interaction partners:
- Next to BRCA1 gene 1 protein
- Ubiquitin-like modifier-activating enzyme ATG7
- Ubiquitin-like-conjugating enzyme ATG3
- Cysteine protease ATG4B
- Ubiquitin-like protein ATG12
- Beclin 1-associated autophagy-related key regulator
- Sequestosome-1
- Cysteine protease
- Autophagy protein 5
- BCL2 interacting protein 3
Sequence:
MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
Protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN2B (EC 3.1.3.48) (EC 3.1.3.67) (Protein PHOSPHATASE AND TENSIN HOMOLOG 2-b) (AtPTEN2b) (AtPTEN3) (Q8H106)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Protein tyrosine phosphatase that exhibits also a weak lipid phosphatase activity towards PtdIns(3)P.
Interaction partners:
- Phosphoinositide phosphatase SAC6
- Phosphoinositide phosphatase SAC8
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1
- Phosphoinositide phosphatase SAC7
- Phosphatidylinositol 3-kinase VPS34
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
- Phosphatidylinositol 4-kinase beta 1
- Phosphatidylinositol 4-kinase beta 2
- Probable CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2
- Putative 1-phosphatidylinositol-3-phosphate 5-kinase FAB1C
Sequence:
METDPANSSSKSPAVVSEKDVLIPEPSENTVGVVQDPVSAEREAHEDSISTEASVAKVDDTQMPASSTGSEPLSKTDDIVPCPPGSSPRESPPSIFSSSGLSSWAKSFKFQQQDPNRTDSGMSAFTRFTSELGLHLPTKGSEEVGDSRSSNTQVGGAFESLTKAVVDSSRGAVKAMQVKARHIVSQNKRRYQEGEFDLDMTYITENIIAMGFPAGDISSGLFGFFEGLYRNHMEEVIKFFETHHKDKYKVYNLCSERLYDASRFEGKVASFPFDDHNCPPIQLIPSFCQSAYTWLKEDIQNVVVVHCKAGMARTGLMICCLLLYLKFFPTAEEAIDYYNQKRCLDGKALVLPSQIRYVKYYERVQNQFDGKVPPERRCMLRGFRLINCPYWIRPAITISNHTDILFSTKKHQKTKDLGPEDFWIKAPKKGVVVFAIPGEAGLTELAGDFKIHFQDSDGDFYCWLNTTLTDNRTMLKGSDFDGFDKRKLPAPGFHVEIVMIEPDNSQPTKSKSDSTQQQSQSSSSADSSKLKSNEKDDDVFSDSDGEEEGNSQSYSTNEKTASSMHTTSKPHQINEPPKRDDPSANRSVTSSSSSGHYNPIPNNSLAVSDIKAIAADASVFSFGDEEEDYESD
Protein: Uncharacterized protein ycf68 (ORF133) (P12173)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
Sequence:
MAYSSCLNRSLKPNKLLLRRIDGAIQVRSHVDLTFYSLVGSGRSGGGTTAPLFSRIHTSLISVWRAISRAQVEVRPQWENGAPNNASSQTKNYEITLSFWGDGGIVPFEPFFHAFPGGLEKAAINRTSLILPS
Protein: Neuropeptide Y receptor type 4 (Neuropeptide Y/peptide YY receptor Ya) (O73733)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MPSALFDMPLWQALLNSTLTHNQSNSSLFLLDVPCWQSSTMTLTLVLCYCLVLILGLLGNILLICIIMHQRDPPNVTSILIANLSVSDILVSVFCLPFTVVYTLMDHWIFGALLCRLMPFVQCVSVTVSVLSLVLIALERHQLILHPSGWKPSVPQAYIAVLTVWLLACVTSLPFLAFHLLTSEPYSLFPAPLSQLQVCLEVWPSQDHKLAYTTSLLLFQYCCPLLLMLLCYLRIFLRLQRRERMLERQCSRNREDEHRRVMHSKRINVMLATLVAAFAVCWLPLNAFNVVADCDQEVLPVCNHNLLFSLCHLLAMSSTCVNPIIYGFLNSNFRKDVASVVLHCHFQPLEDSYEHFPMSTMNTDVSRTSFRLRNNSV
Protein: Heterogeneous nuclear ribonucleoprotein A/B (D6RD18)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGQGSTNYGKSQRRGGHQNNYKPY
Protein: Septin-type G domain-containing protein (Q8I4C9)
Organism: Caenorhabditis elegans
Interaction partners:
- Septin
- Anillin-like protein 1
- Kinesin-like protein
Sequence:
MSFETILYTASALLFIFLLVLLTTAFLIVRRSKQSSINLQTVVVTHENPYVTMTSQSSKMDIPVILPKRFNMSDIEHKHLPPHQPPPPVPHHHQNQPTHNNTTTISSATSSINTTTTSKKPTIAAPTAPSPIKSLSDHTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGKTTLIESLFNMKLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVDYLESQFETYLQEELKPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAKSDTTCKDELLRFKAKILSELKSQKIDIYTFPTDDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQMVRARQYPWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGETGPKIIEKLAQKHREHQDEFSRRELTLREEFQKKLDVTEGDMRKVEEGLAAREREVHENYNREASKLDMEIRQLTEERMKLMTKVSKKLRK
Protein: Segregation and condensation protein A (Q97NX5)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
Interaction partners:
Sequence:
MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVSTLQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLLGEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLTFSNILAKKKEEFAQNHTTILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELILVQEESFGDIYLMEKKEESQVPQS
Protein: Long-chain-fatty-acid--CoA ligase 2 (EC 6.2.1.3) (Fatty acid activator 2) (Long-chain acyl-CoA synthetase 2) (P39518)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Activates endogenous medium-chain (MCFA) and long-chain fatty acids (LCFA) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. Preferentially acts on C9:0-C13:0 fatty acids although C7:0-C17:0 fatty acids are tolerated. Is the main if not exclusive MCFA (octanoate, decanoate and laureate) acyl-CoA ligase. Required for efficient MCFA beta-oxidation inside peroxisomes. Facilitates the transport of MCFAs into peroxisomes by passive diffusion, by decreasing the intraorganellar MCFA concentration. Also esterifies LCFAs in the peroxisome matrix. The LCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:7988550}. Peroxisome membrane {ECO:0000269|PubMed:8670886}; Peripheral membrane protein {ECO:0000269|PubMed:8670886}; Matrix side {ECO:0000269|PubMed:8670886}. Note=Imported via the peroxisome targeting signal type 1 (PTS1)-dependent protein import pathway. {ECO:0000269|PubMed:8670886}.
Interaction partners:
- Acyl-coenzyme A oxidase
- Peroxisomal membrane protein PMP27
- Fatty acid synthase subunit beta dehydratase; Enoyl-[acyl-carrier-protein] reductase; [Acyl-carrier-protein] acetyltransferase; [Acyl-carrier-protein] malonyltransferase; S-acyl fatty acid synthase thioesterase]
- Fatty acid synthase subunit alpha reductase
- Peroxisomal long-chain fatty acid import protein 1
- Peroxisomal long-chain fatty acid import protein 2
- Peroxisomal hydratase-dehydrogenase-epimerase
- Long-chain-fatty-acid--CoA ligase 1
- Long-chain-fatty-acid--CoA ligase 3
- Long-chain-fatty-acid--CoA ligase 4
Sequence:
MAAPDYALTDLIESDPRFESLKTRLAGYTKGSDEYIEELYSQLPLTSYPRYKTFLKKQAVAISNPDNEAGFSSIYRSSLSSENLVSCVDKNLRTAYDHFMFSARRWPQRDCLGSRPIDKATGTWEETFRFESYSTVSKRCHNIGSGILSLVNTKRKRPLEANDFVVAILSHNNPEWILTDLACQAYSLTNTALYETLGPNTSEYILNLTEAPILIFAKSNMYHVLKMVPDMKFVNTLVCMDELTHDELRMLNESLLPVKCNSLNEKITFFSLEQVEQVGCFNKIPAIPPTPDSLYTISFTSGTTGLPKGVEMSHRNIASGIAFAFSTFRIPPDKRNQQLYDMCFLPLAHIFERMVIAYDLAIGFGIGFLHKPDPTVLVEDLKILKPYAVALVPRILTRFEAGIKNALDKSTVQRNVANTILDSKSARFTARGGPDKSIMNFLVYHRVLIDKIRDSLGLSNNSFIITGSAPISKDTLLFLRSALDIGIRQGYGLTETFAGVCLSEPFEKDVGSCGAIGISAECRLKSVPEMGYHADKDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRISVIDRVKNFFKLAHGEYIAPEKIENIYLSSCPYITQIFVFGDPLKTFLVGIVGVDVDAAQPILAAKHPEVKTWTKEVLVENLNRNKKLRKEFLNKINKCTDGLQGFEKLHNIKVGLEPLTLEDDVVTPTFKIKRAKASKFFKDTLDQLYAEGSLVKTEKL