wanglab/gogpt-training-data huggingface dataset:
Protein: Latexin (Endogenous carboxypeptidase inhibitor) (ECI) (Protein MUM) (Tissue carboxypeptidase inhibitor) (TCI) (Q9BS40)
Organism: Homo sapiens (Human)
Function: Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Carboxypeptidase A4
- Carboxypeptidase A2
Sequence:
MEIPPTNYPASRAALVAQNYINYQQGTPHRVFEVQKVKQASMEDIPGRGHKYHLKFAVEEIIQKQVKVNCTAEVLYPSTGQETAPEVNFTFEGETGKNPDEEDNTFYQRLKSMKEPLEAQNIPDNFGNVSPEMTLVLHLAWVACGYIIWQNSTEDTWYKMVKIQTVKQVQRNDDFIELDYTILLHNIASQEIIPWQMQVLWHPQYGTKVKHNSRLPKEVQLE
Protein: Derlin-1 (Coelomocyte uptake defective protein 2) (DER1-like protein 1) (cDerlin-1) (Q93561)
Organism: Caenorhabditis elegans
Function: Specifically required for the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9BUN8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9BUN8}.
Interaction partners:
- S5 DRBM domain-containing protein
- E3 ubiquitin-protein ligase hrd-like protein 1
- Derlin-2
- E3 ubiquitin-protein ligase hrd-1
- Ubiquitin fusion degradation protein 1 homolog
- Transitional endoplasmic reticulum ATPase homolog 2
- Endoplasmic reticulum lectin 1
- MRH domain-containing protein
- UBX domain-containing protein 2
- Transitional endoplasmic reticulum ATPase homolog 1
Sequence:
MDLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDLVVNKFQFWRPLTALIYYPVTPQTGFHWLMMCYFLYNYSKALESETYRGRSADYLFMLIFNWFFCSGLCMALDIYFLLEPMVISVLYVWCQVNKDTIVSFWFGMRFPARYLPWVLWGFNAVLRGGGTNELVGILVGHAYFFVALKYPDEYGVDLISTPEFLHRLIPDEDGGIHGQDGNIRGARQQPRGHQWPGGVGARLGGN
Protein: Probable galactarate/D-glucarate transporter GarP (P0AA80)
Organism: Escherichia coli (strain K12)
Function: Probably involved in the uptake of galactarate and/or D-glucarate (Probable). May also transport D-glycerate (Probable).
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- 5-keto-4-deoxy-D-glucarate aldolase
- 2-hydroxy-3-oxopropionate reductase
- Galactarate dehydratase
- Glucarate dehydratase-related protein
- Uncharacterized protein YnfO
- Probable galactarate/D-glucarate transporter GudP
- Inner membrane transport protein RhmT
- Uncharacterized protein YgaC
Sequence:
MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK
Protein: Dual specificity protein phosphatase 13A (DUSP13A) (EC 3.1.3.16) (EC 3.1.3.48) (Muscle-restricted DSP) (Q6B8I0)
Organism: Mus musculus (Mouse)
Function: Probable protein tyrosine phosphatase. Has phosphatase activity with synthetic substrates. Has a phosphatase activity-independent regulatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q6B8I1}.
Interaction partners:
Sequence:
MADASIPKPGEEKEATPCPSILQLEELLRAGRASCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHGGLYCQGGPDFYGSSVCYLGIPAHDLPDFNISPYFSSAADFIHRALTVPGAKVLVHCVVGVSRSATLVLAYLMLHQQLSLQQAIITVRERRWIFPNRGFLRQLCQLDQQLRGAGQS
Protein: Meiotically up-regulated gene 154 protein (P87236)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Lap-Emerin-Man domain protein 2
- Meiotically up-regulated gene 61 protein
- Charged multivesicular body protein 7
Sequence:
MGKLIRRTSLTSKIINLPIDYFIYVCEQFDSVEWDKVSDRYSIPFSLAVNFIFLLMRIYIKSTHVPVQRNQLFVDKQSINTSRSWFRAFLSFLSICFLFISFLNFIFSTRFQNKLYRTLPQDKRTTTSTPNVKPVFQHSNNDDGDEQVFELKVWSPNQFLLNFACLFSPAHALILWFYSTSLRVTLLTFLLSFTTLHFVNKFSLLLKDQQYLHRQVFFEYDKKFVEPRLSVVKRDVAINTTRGPTTASIEYFTPRKPIDTFLEHRSSSHDHLTSTPRTPIALQRRSVHHLHDSGISRDSSSPFKRFPHLSDGSSRF
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (Q4WHW6)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR000909}.
Interaction partners:
- WD repeat protein
- RNA polymerase II subunit A C-terminal domain phosphatase ssu72
- Polyadenylation factor subunit 2
- Zinc knuckle domain protein
- Serine/threonine-protein phosphatase
- Endoribonuclease ysh1
- Protein cft1
- Cleavage and polyadenylation specificity factor subunit 2
- Protein phosphatase PP1 regulatory subunit Sds22, putative
- mRNA 3'-end-processing protein yth1
Sequence:
MGQSHSKGNSGPGDSLQSYPSFSRSDTKESLRSLRGSIRSKIRSSDSPRGSTAGLSDDKSDAASVKSTTSRRSSTNQSVQSPDDTPSQPDAPEPPPSPSLSSSLKRGHKDVNAMQQSGEVDHVSDVPPTGAAPTGPSTQKVGESILIKRENQLNPILDFIMNAPLETSGSPGMGMGALKSIDLDDMISRLLDAGYSTKVTKTVCLKNAEIMAICSAARELFLSQPALLELSAPVKIVGDVHGQYTDLIRLFEMCGFPPASNYLFLGDYVDRGKQSLETILLLLCYKLKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKIWKTFIDTFNCLPIAATVAGKIFCVHGGLSPSLSHMDDIRGIARPTDVPDYGLLNDLLWSDPADMEEDWEPNERGVSYCFGKKVIMNFLQRHDFDLVCRAHMVVEDGYEFYQDRILVTVFSAPNYCGEFDNWGAIMSVSGELLCSFELLKPLDSTALKNHIKKGRKERNSMLSSPVSPPLLRFVVAKEDHNLFVQHRRDACGLFLAYPSLVTSWGISR
Protein: Rust resistance kinase Lr10 (EC 2.7.11.1) (Probable receptor-like serine/threonine-protein kinase LRK10) (P93604)
Organism: Triticum aestivum (Wheat)
Subcellular location: Cell membrane {ECO:0000269|PubMed:9700067}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSKLLVIALLLLPLINHGIYLATAWDDQDFFKYCPPSKCSQHGPMIRYPLCLESSNTSSSSSCGCAGRSIWKLACSGQDTILVHPVLGPYSVSAIDYRRSSMKITPLVDPCLVLQQKLIISRSSSSPQVDVINDEKPSFDENFFESSSATIVHCSREFTPAAAHADSIAGPVSCLSNTTHFFYLVNSDEDMSILPLDCKVVPVSDRGGISLPHMLKDQMFYNFTETAKKIPSFAETAVSWDEGDCRECELSGRRCAFSSQRDREFCMPDPHGSHIKVIAATSSVAAFVALLLTVATVLYLSLKTRYNAEIHMKVEMFLKTYGTSKPTRYTFSEVKKMARRFKEKVGQGGFGSVYKGELPNGVPVAVKMLENSTGEGESFINEVATIGLIHHANIVRLLGFCSEGMRRALIYEFMPNESLEKYIFSDDSNIFQNLLVPEKLLDIALGIARGMEYLHQGCNQRILHFDIKPHNILLDYNFNPKISDFGLAKLCARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKADVYSFGMLVLEMVSGRRNSDPRIGSQDDVYLPEWIYEKVINGEELALTLETTQEEKDKVRQLAMVALWCIQWNPRNRPSMTKVVNMLTGRLQSLQMPPKPFVSSENELMS
Protein: Aerolysin (P09167)
Organism: Aeromonas hydrophila
Function: Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and host cell death. The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter.
Subcellular location: Secreted. Host cell membrane. Note=Secreted as a soluble precursor.
Interaction partners:
Sequence:
MQKIKLTGLSLIISGLLMAQAQAAEPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGMMGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPVTGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAHYLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDGYRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVVGWAVNDSDTPQSGYDVTLRYDTATNWSKTNTYGLSEKVTTKNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPTVPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYIPGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGITGDFSAESQFAGNIEIGAPVPLAADSKVRRARSVDGAGQGLRLEIPLDAQELSGLGFNNVSLSVTPAANQ
Protein: Transcriptional activator GLI3 (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcriptional repressor GLI3R (GLI3 C-terminally truncated form)] (Q9IA31)
Organism: Gallus gallus (Chicken)
Function: Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor.
Subcellular location: Nucleus. Cytoplasm {ECO:0000250}.
Interaction partners:
- Suppressor of fused homolog
- Kinesin family member 7
- Speckle type BTB/POZ protein like
- Speckle type BTB/POZ protein
- Kinesin-like protein
- Sonic hedgehog protein
- cAMP-dependent protein kinase
- Protein smoothened
- Uncharacterized protein.
- Cullin 3
Sequence:
MEAQSHSSTTTEKKKVENSIVKCSNRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITMQPQGGQGLSKISEEPSTSSEERASLIKKEIHGSISHLPEPSVPYRGTLVTMDPRNGYMDPHYHPPHLFQAFHPPVPIDARHHEGRYHYEPSPIPPLHVPSALSSSPTYSDLPFIRISPHRNPAAASESPFSTPHPYINPYMDYIRSLHSSPSLSMISAARGLSPTDAPHAGVSPAEYYHQMALLAGQRSPYADIIPSAATAGAGALHMEYLHAMDSTRFPSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSCSSWSASGSYGHLSASAISPALSFTYPPTPVSLQQMHQQIISRQQTLGSAFGHSPPLIHPAPTFPTQRPIPGIPSVLNPVQVSSGPSESTQHNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGAGSVQEQPEGMTPVKEEGDKDESKQEPEVVYETNCHWEGCSREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDPGSHSQTRSPGQQTQGATGEQKDLNSTTSRREECLQVKAVKSEKPMTSQPSPGGQSTCSSEQSPISNYSNNGIELTLTGGGSVGDLSVIDETPIMDSTISTATTALGLQARRNMTGTKWMEQVKLERLKQVNGMLPRLNPVPPSKAPTLPPLIGNGTQSNSSCSVGGSMTILPNRNELSSTDITVLNMLNRRDSNTSTISSAYLSSRRSSGISPCFSSRRSSDASQAEGRPQNVSVADSYDPISTDASRRSSEASQCDDLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRMALLGDCRESGISPLPPVNAPRRCSDGGANGYSRRHLLSHDALGNGTRRASDPVRMVSNNLSVPRVQHFNSLNSFNSPALPPSMEKRNLVLQNCTHSEGGVFRGFSSPCPPSISENVTLEAVTMEAGGSLNDEDLLPDDVVQYLNSQNQGTCDHLLNNVLDSNKMHHSVVLGNNNPSSFDRAPPASSQPAGSEVSKSDLPIQWNEVSSGSSDLSPTKLKCSQRSAVQQARAFGLYNNMMVQQQNLQRGNVYQQNGYQNLMENNGSYSLQQNTVLGSGASSSFGMQPNKPYGESVSRQPMIFGAMDSSCGITVQGQKLRSSNMPVSGNQQNFGHPIASSDQATSMANGMQNRNVMEQEYLQNELVGDGIHYQGVNQSSPMTLGQVSPTSQSSLHQGPQSCPPVSHTIGNQSSGLSVAKSYQPCANYSGNRRQNVLRNNLAQQQGHVSDGNQTYRVNTIKLEMQGQSQQFCSNMQNYSGQLYDQTTGFSHQAMKIGSSFFVSEANCLLQETATANSSELLSPGANQVSSTVDSLDSNSLEGVQIDFDAIIDDGDHVSLISGALSPSIIQNLSRNSSRLTTPRASLTFP
Protein: ATP-dependent RNA helicase WM6 (DEAD box protein UAP56) (Dmrnahel) (EC 3.6.4.13) (HEL/UAP56) (Q27268)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for mRNA export out of the nucleus. Probable RNA helicase that may regulate entry into mitosis by down-regulating the expression of other genes whose activity may be rate-limiting for entry into mitosis during embryogenesis. Binds to salivary gland chromosomes and modifies position effect variegation. Promotes an open chromatin structure that favors transcription during development by regulating the spread of heterochromatin.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:11696332, ECO:0000269|PubMed:9215899}. Note=Locates to nuclei of embryos and ovaries, but disappears in mitotic domains of embryos as chromosomes condense.
Interaction partners:
- THO complex subunit 2
- RNA and export factor binding protein 2, isoform A
- LD24793p
- Eukaryotic initiation factor 4A-III
- THO complex subunit 5
- Hpr1
- THO complex protein 7
- LD31448p
- RNA-binding protein 8A
- FI07663p
Sequence:
MADNDDLLDYEDEEQTETTAVENQEAPKKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQISKEYERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGLQQHYVNLKENEKNKKLFELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRFDVNISELPEEIDLSTYIEGR
Protein: Muc3 protein (Q91WF4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
ITTLAPTTTAVNCMNGGFWTGDKCICPNGFGGDRCENIVNVVNCENGGTWDGLKCQCTSLFYGPRCEELVESVEIEPTVAASVEVSVTVTSQEYSEKLQDRKSEEFSNFNKTFTKQMALIYAGIPEYEGVIIKNLSKGSIVVDYDVILKAKYTPGFENTLDTVVKNLETKIKNATEVQVQDVNNNCSALLCFNSTATKVQNSATVSVNPEETCKKEAGEDFAKFVTLGQKGDKWFCITPCSAGYSTSKNCSYGKCQLQRSGPQCLCLITDTHWYSGENCDWGIQKSLVYGLGGAGVAVLLVILVILLVFSIRFRKDAQRQRSRVSEMYKWGEEEGRASPGTFHNFGFDHNEERENYMPLDSVYNTFQPSLNHINPERKIQIQRPQVVMTSL
Protein: Meiosis-specific kinetochore protein (Q5F2C3)
Organism: Mus musculus (Mouse)
Function: Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.
Subcellular location: Chromosome, centromere {ECO:0000269|PubMed:25533956}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:25533956}. Note=Localizes at kinetochores in meiosis I but undetectable in meiosis II. {ECO:0000269|PubMed:25533956}.
Interaction partners:
- Serine/threonine-protein kinase PLK1
- Meiotic recombination protein REC8 homolog
Sequence:
MDKIWHMGPRGDYTRKKRAGERLNLTPKPDLALPGRTEALPGLKGKGKEQGLRKITEKKELSRLTGSSSQRPSLLSVTGGEHLQENSPGQETPEEKTPPCETVTDTFEMDSLLSSTELVSGPAEQDDFSSCLPSCSNAELHTESTDERGSSFPSPELFRGSDCLDWEHPKLEDYMFYKNSTLLDTSKAVVIEKAPQFANLSAVLSSSSKNYEKRHRKIGMTLAAQHLSPEPKYASNLASVVDNAASEVVFAEKTGPPTTEKTQKKPENESEDSGPLVQTKLSSGHPDNKALCSPLSSALESTAVRYTLLPQPLEPVLKKGCILPDKQSKALLTSTPSSDIAEFVIDLSPVQNVSFEELFPNVSNYVNSSEVVPVSSLQESSSNEFSPNTSEICCIIRSSPGTRQMRRKDPAVKNRCSPPKDVPLDIIMKTNGRT
Protein: Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C) (Q93W34)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Sm protein F
- Splicing factor YJU2
- THO complex subunit 4B
- Aspartic proteinase 39
- Probable protein phosphatase 2C 33
- Protein FATTY ACID EXPORT 5
- Vacuolar protein sorting-associated protein
- Large ribosomal subunit protein uL15c
- Nascent polypeptide-associated complex subunit alpha-like protein 2
- Eukaryotic translation initiation factor 2 subunit alpha homolog
Sequence:
MMQQPPPASNGAATGPGQIPSDQQAYLQQQQSWMMQHQQQQQGQPPAGWNQQSAPSSGQPQQQQYGGGGSQNPGSAGEIRSLWIGDLQPWMDENYLMNVFGLTGEATAAKVIRNKQNGYSEGYGFIEFVNHATAERNLQTYNGAPMPSSEQAFRLNWAQLGAGERRQAEGPEHTVFVGDLAPDVTDHMLTETFKAVYSSVKGAKVVNDRTTGRSKGYGFVRFADESEQIRAMTEMNGQYCSSRPMRTGPAANKKPLTMQPASYQNTQGNSGESDPTNTTIFVGAVDQSVTEDDLKSVFGQFGELVHVKIPAGKRCGFVQYANRACAEQALSVLNGTQLGGQSIRLSWGRSPSNKQTQPDQAQYGGGGGYYGYPPQGYEAYGYAPPPQDPNAYYGGYAGGGYGNYQQPGGYQQQQQ
Protein: Protein LTV1 (Q10191)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in protein transport. Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit. May participate in intracellular sorting of GAP1 out of the endosome (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
Interaction partners:
- Serine/threonine-protein kinase rio2
- Uncharacterized protein C13G1.09
- Small ribosomal subunit protein uS3
- Ribosome biogenesis protein tsr1
- Pre-rRNA-processing protein pno1
- 20S-pre-rRNA D-site endonuclease nob1
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS5
- Serine/threonine-protein kinase rio1
- Small ribosomal subunit protein eS21
Sequence:
MGKKKFVNKNKAQTFHLVHRSQRDPQYHDENATERVLVSAETLNKTARRLNRQTLDEEYGSTIRPNEGEAANYGIYFDDTEYDYMQHLRNIGNEDATWVEAPATRKTQDKQKKQQIQLRDQPSILPQEVLPSEVELERTYQDQQSVPDAISGFQPDMDPRLREVLEQLEHSDINDEETSDFDEEFEKLVASGKADESEFYAQPFVEEGEKDYDEAAAAKAGKSEWEIEFEKFKLEQKKQPDVASSDGDFSDEPESEERDEVPELVSSSKSKSKTKRKARTALSSVSMSSSALFRNEGLTLLDDRFDKVEEEYTPIKDERELIDPDQKDVFDLVNDNQFNDIMDEFLVSYGPTLGRKKAPSRMSNSKKKSSLEELDNVRKMLGRARI
Protein: Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) (Q21270)
Organism: Caenorhabditis elegans
Function: Required for normal Golgi function.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 2
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 4
- Immediate early response 3-interacting protein 1
- Gelsolin-like protein 1
- t-SNARE coiled-coil homology domain-containing protein
- Putative syntaxin-5
Sequence:
MSVIDKTSSAVNPLREKVTTACAKKLYNDKDCIKIADFITPLVEDMNLDSNVDRKLHNKLERYELRLNKEYLSEFEKINNIVQKFDELCVKMNSTCTNLSKQMETVKFKSVDLVQKTASLKEKKASIESRCNMINEFLENYSLSSEELRELDECEQSGHLSEFFFKVLERCHEIRENCRNMVQEQGHLAAFEVMEKMQKIDERSHAIICNNLKREFQNLTVDSHQKKQILSKAFKIISQNDAVFQLAIDQYISSRSQELLNQFVEINKMAVQMPEGLAEPLKAVGDMLTSIHELTEQEKQLFSSICSAENLPIVLDECLKSLTSPFKIRVEQLLSTEKNAITIFKMGNILIFYANKFETLIRKDSYFTIMLADLVKTVRQVCIAGINHHVDGLMRKMTSPHYDLLPVPEVRQCLSLYHGLISIAVKTGDLNLLLEPERIYEYVLEPLIQTVQLSATRLKSDIEVSVFTINCLTVIRSAISEISAFKKKIEMIDAMIEGNSDVLVSVQVSEMLEKSGILELYQKFNAVNPAEKKPLSTLPGLESTTVGEAIVMFTQYLHNHASSDHTYDIDQQILASEERQRIRERNTLEFLKVYKMIVDRLGNPTNGYENLHYLPIEHVESVLKFEKEKENTPSSNESESLA
Protein: 26S proteasome regulatory subunit rpn2 (O74762)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Interaction partners:
- 26S proteasome regulatory subunit rpn11
- 26S proteasome regulatory subunit rpn8
- 26S proteasome regulatory subunit 6A
- Probable 26S proteasome subunit rpt4
- 26S proteasome regulatory subunit 8 homolog
- 26S proteasome regulatory subunit 7 homolog
- Probable 26S proteasome regulatory subunit rpn9
- 26S proteasome regulatory subunit rpn1
- Probable 26S proteasome regulatory subunit rpn3
- 26S proteasome regulatory subunit rpn10
Sequence:
MTMVYSDNTSIITSAGGLMALLDEQERELQVHALLKIYEFIDQLWPEISDDVTKIEVMYEDHSFPERELAALVVSKVYYYLGEYDEALLFALSSGPKFLHDKNSDYKETLIFKCIDMFIHKSAELYKNPKADPLDERLSGVVEGIFQKCYAKNEWRHVLGIAIEAHRLDIIEYILNADKETDLKPYVLELAMTVVLDIEFRNRLLRLLLSSFLTETEPDYFSVGKCVVHLNDASVAAKLLMKLSSQNDDKSLLTAYQLAFDLEDSAPQEFLNSVMDLLPSPSVANSEEDANADSKKEDSSPCGYIIRILSGEQTVKYDREFLYAHNNTDMLILNRTKDSLEARNSVFHNAVTFANAFMNFGTSSDSFFRDNLSWLSKANNWSKFTATAALGVIHRGYYNQAMNILRPYLPEEDAPSSSTYSEGGAFYAMGLIHANHGRGVTEYLREQLKHTEDEIVQYGLLLGIGLTGMASRDETLYESVKTILFNDNAVAGSAAGISMGLIMLGTASSAAIDEMLQYAHETQHEKIIRGLGIGIALIVYGRQQEADGIIKELNNDLDPTLRYAGMFATALAYCGTSNSKIVRDVLHISVSDVNDDVRRAAVCALGFICFKDPNALISTVELLVDSYNPHVRYGSAIALGIACANSGSNAALDLLSRLVEDATDFVRQGAMIAQAMILTQHNDQLNSKVSGIRKHFEQVINEKHEDALAKLGATLAQGIIDAGGRNVTIALQTATGSLKLSAIVGLTVFLQYWYWFPLTHFMSLSFSPTALIGLDKNLNAPKFSFISNVRPKLFAYPPKSVQPTAKTVQKVETAVLSTTVKAQARAKRAEREKASKGSNDDEMKIDKKTTEEKEATPMEMDEEKSQDISINGNSKKEEPKSETLENFTRVVPAQLPYISFNLNGRYYPVRKFTGGVLMLIDRESDKAPDLIELNRDAVPASADTEPGEQEASPPEDFEYPFDDDD
Protein: Alkanal monooxygenase alpha chain (EC 1.14.14.3) (Bacterial luciferase alpha chain) (P19907)
Organism: Aliivibrio fischeri (Vibrio fischeri)
Function: Light-emitting reaction in luminous bacteria.
Interaction partners:
Sequence:
MKFGNICFSYQPPGETHKLSNGSLCSAWYRLRRVGFDTYWTLEHHFTEFGLTGNLFVAAANLLGRTKTLNVGTMGVVIPTAHPVRQLEDVLLLDQMSKGRFNFGTVRGLYHKDFRVFGVDMEESRAITQNFYQMIMESLQTGTISSDSDYIQFPKVDVYPKVYSKNVPTCMTAESASTTEWLAIQGLPMVLSWIIGTNEKKAQMELYNEIATEYGHDISKIDHCMTYICSVDDDAQKAQDVCREFLKNWYDSYVNATNIFNDSNQTRGYDYHKGQWRDFVLQGHTNTNRRVDYSNGINPVGTPEQCIEIIQRDIDATGITNITCGFEANGTEDEIIASMRRFMTQVAPFLKEPK
Protein: Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma) (P48443)
Organism: Homo sapiens (Human)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407, ECO:0000269|PubMed:28167758}. Cytoplasm {ECO:0000269|PubMed:28167758}.
Interaction partners:
- Nuclear receptor coactivator 2
- Retinoic acid receptor alpha
- Retinoic acid receptor beta
- Peroxisome proliferator-activated receptor gamma
- Oxysterols receptor LXR-alpha
- Retinoic acid receptor gamma
- Oxysterols receptor LXR-beta
- Retinoic acid receptor RXR-alpha
- Retinoic acid receptor RXR-beta
- Paired box protein Pax-8
Sequence:
MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
Protein: Putative uracil phosphoribosyltransferase urg2 (UPRTase urg2) (EC 2.4.2.9) (UMP pyrophosphorylase urg2) (Q9US43)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uridine kinase
- Uracil phosphoribosyltransferase 2
- Uridylate kinase
- Protein urg3
- Uracil-regulated protein 1
- Putative purine nucleoside phosphorylase
- Orotidine 5'-phosphate decarboxylase
- Uracil phosphoribosyltransferase 1
- Golgi apyrase
- Pseudouridine-metabolizing bifunctional protein C1861.05
Sequence:
MSTTTTVSAIRTVEEMSNITISSHPVVNEQIAILRDRSLKPSQVRSVVDEISRFLAYESTKTLKSPSVSIVPVLRSGMSMMSAFSKVLPDVPIYHIGIFREKSTLQPIEYYNKLPKKSTDTAVILDPVMATGGTANAVITTLQEWGCKNIIFVSVLASEQALTRFSNIPGVEFVIGAVDKSLDAKGYLVPGVGDIGDRLYGATA
Protein: Photosystem I P700 chlorophyll a apoprotein A1 (EC 1.97.1.12) (PSI-A) (PsaA) (P0C355)
Organism: Oryza sativa subsp. japonica (Rice)
Function: PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00458}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00458}.
Interaction partners:
- Photosystem I iron-sulfur center
- Photosystem I reaction center subunit III
- Photosystem I reaction center subunit II
- Photosystem I P700 chlorophyll a apoprotein A2
- Photosystem I iron-sulfur center
- Os07g0435300 protein
- Photosystem I reaction center subunit IX
- Photosystem I reaction center subunit VIII
- Photosystem I assembly protein Ycf3
- Photosystem I reaction center subunit psaK, chloroplastic
Sequence:
MMIRSPEPEVKIVVDRDPVKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTGDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALIFASLMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQIHVSLPINQFLDAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYAEFLSFRGGLDPITGGLWLSDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSTTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWVQNLHAGAPSVTAPGATTSTSLTWGGGELVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGTISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG