wanglab/gogpt-training-data huggingface dataset:
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (Q9W0L7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- AT27578p
- tRNA selenocysteine-associated protein 1
- Caprin homolog
- DNA-directed RNA polymerase II subunit RPB1
Sequence:
MASTSSSASTTAGSSGAAGGGAATPISTPSTPQPSGVSSGPGNNGNNNNNHHNNTLVSPSGNNNLMTPVQAFTPTGQPVYNPPVYMSAHGGHPHAGAHYPAMIPAPMPSNHVYVNNVTANVNLHGWPHGVPAYMPPGGQHHYIGHGDMPQEQGNTVMPHLQPVPINLAPQGGSPNPHGPRMGGGRMRERGRPRGGGPRRNDYHGPRHLQQQQLITLPPQQQLPPPDGANPGLQLQPDQIGQQLAPPEAHMQHLQQYYAAPPTYAYGPYPSPYFTPQHANVQPPPNATAAQQATGTPLFISGPLMYNPAWFNHGGYIYPMMHPAEYQYVPEDAGQPGVDERGAQPDGGMTQIWHQGPMYAEDFEALQQQQQQQQVAVHPNGGAVSVADELNHNSSSLPSSETSSMISPNYPIYDPQMHEMQHQMGVMQIFDDGQMAALQPIHPGAGPLPQYEDELAECGAPPPGPIPVAWTAAMPLPPDAVQPALLPPPPHHILQQTSPLLIEQPAQLVQAQPPQPPTPTPQQQQQQQHQEQTADKSLTQNNNEVVALDEKLANEKQQQIDFHQQQQEQQQQQQQQQQQQQLHPLAQQQQQEEQQQPQQLQPLQTEKPPTKVPNLVVATVAPQLQQPPLQQHQQQQTSPVVVSPKQQQQQSQAAHQNSYHDQHPLPQQQQPQQQQPQPQRKPSQQYNQAQQQQVRRKYSSEYNHHHHQHGSSDTGIQTTKTMSWTNSAQHKKSTQSVSVTASPNSVNNGPGVGAAGKANYSHTTKTFTNQQHYQQQHYHTQNSYNNNSSGGGSSSNSSSSSSNNQPQVRNYGTMKMPSSPVAWTAPTPERKNSQQAAAAPAAATASAAPVAITTVTTSTASITATPNQFQPETGSSSASPAVAAAQQQQPAAQQHAQAAQTGAAAAPSKSHSNYASSKKHQSYEPVVLSSVVATSSSANPQPQLNLAPPAPPASQNSSDSSQLSWASLFASNKPVAKVAPYEASKIAQQQPSHPVLQLAPPQPAQVAAAAPVAQLSSPPQNLPLPTAHQQSQLPAPVPAPTAPLVTPGALSYSAASAQAVPAPSPASASVKPLKPEPPRPVQQQLDEWTSKYAEYLTRHKTNLASISLRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVKTPTVNAMMSFMTNFSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDMAFEPTEIYKLWNDSREEHVEGRQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAEPEDGGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGELRSRLQREGEHSTDVIQPFFTLQLNIEKAASVKEALEILVGRDQLEGVTGSKTKQEVVAWQQMTLEKLPVVLILHLKYFDYRSDGCTKILKKVDFPVELKIDAKILGSKKTSQKQRAYRLFAVVYHDGKEASKGHYITDVFHTGYSSWLRYDDSSVKPVSEKHVLQPHTPRVPYLLYYRRSDTLPPQQQQTQQQNGGGSGGVVGSSSSSSNAGDNK
Protein: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (mBACURD3) (BTB/POZ domain-containing protein KCTD10) (Q922M3)
Organism: Mus musculus (Mouse)
Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9H3F6}.
Interaction partners:
- Cullin-3
- UBX domain-containing protein 7
- UBX domain-containing protein 1
- FAS-associated factor 1
- B9 domain-containing protein 1
- BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
- BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1
- E3 ubiquitin-protein ligase RBX1
- Tectonic-2
- Jouberin
Sequence:
MEEMSGDSVVSSAVPAAATRTTSFKGASPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGGVPLPESRREIEELLAEAKYYLVQGLLEECQAALQNKDTYEPFCKVPVITSSKEEQRLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERERIERVRRIHIKRPDDRAHLHQ
Protein: Alkaline phosphatase (EC 3.1.3.1) (Q54Y02)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Folic acid synthesis protein FOL1
- Low molecular weight phosphotyrosine protein phosphatase
- Probable acid phosphatase DDB_G0284755
- GTP cyclohydrolase 1
- 6-pyruvoyl tetrahydrobiopterin synthase
- Thiamin pyrophosphokinase thiamin-binding domain-containing protein
- Uncharacterized protein
- Ankyrin repeat-containing protein
- F-box domain-containing protein
- Glycerophosphodiester phosphodiesterase
Sequence:
MEQAPNSSSIRESGIGGGGGGGGGGNDKDEMDGSTAIPMEPMTSSSGVSSGGGGKVVSHFLLEEDFDSKKRFTSTHKRIFYILTSLAILVTVVLLIVFLLPRGWEGPKKKTNIIMMIGDGMGPAALTMARVCFHTKGESTSQAHLHLDPYIVGTVKTYSSNSVVTDSAAAATAYASGVKTYNNAVGVDANGKPAGTIIEAAKKLGMKTGLVVTTRISDATPACYFAHSATRHDEAFIIDQLLDKEIDVILGGGKQFFSNKTLQDAVSSKYNYSYVESKQEMEQVEAGRILGLFADYNIPWEIDRLRDPTLLSTKPSLQEMTTKALNLISQNNENGFFLMVEGSKIDVAAHINDAPTQIWETDAFDQTFNLVREWAEKDGNTIVIVTADHETGGLTLANQMVIDGNPKYSWSPETLLTVNKSADLMAELIKGGADPTKLIFDNTGYTLTSDDLKEINRTKSAYYLNQVIGRIVSNYADIGFTTGGHTGEDVNLYTFGDTISEGKFETRLKDHQTEIVDNYIDPILRGNINNIDIASFIIKTLNLDIQSITESLKDFIPKP
Protein: Chymotrypsin-C (EC 3.4.21.2) (Caldecrin) (Q99895)
Organism: Homo sapiens (Human)
Function: Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity.
Interaction partners:
- Serine protease inhibitor Kazal-type 1
- Carboxypeptidase A1
- Bile salt-activated lipase
- Chymotrypsin-like elastase family member 3A
- Carboxypeptidase A2
- Cystic fibrosis transmembrane conductance regulator
- Colipase
- Chymotrypsin-like elastase family member 3B
- Pancreatic polypeptide prohormone
- Inactive pancreatic lipase-related protein 1
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
Protein: 17-beta-hydroxysteroid dehydrogenase type 4 (Hsd17b4 protein) (Hydroxysteroid (17-beta) dehydrogenase 4) (Peroxisomal multifunctional enzyme type 2) (Q8AYH1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
Interaction partners:
- Acyl-coenzyme A oxidase
- Acyl-coenzyme A oxidase
- 3-ketoacyl-CoA thiolase, peroxisomal
- Sterol carrier protein 2
- GTPase Era, mitochondrial
- Thrombospondin-type laminin G domain and EAR repeat-containing protein
- Peroxisomal biogenesis factor 5.
- Enoyl-CoA delta isomerase 2.
- Peroxisomal bifunctional enzyme
- Peroxisomal membrane protein PEX13
Sequence:
MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVEEIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQRVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAIEGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVGAGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLSRVEDERKIGANPTAVATNPAQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQLQFLYEGHTHFSCLPTFGVIPAQGALLGLGSIPGLDIDFTRLLHGEQYLELYKPLPTSGTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVAPAAPPDRPADAVVVEETSRDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFAARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSGAYIDLHPAASVNTGPPQTELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGETRRHWTVDLKTGRGSVQRAAAKADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNIMLSQKLEAVLKDQARL
Protein: Vesicle-associated membrane protein-associated protein SCS2 (VAMP-associated protein SCS2) (Choline sensitivity suppressor protein 2) (VAP homolog 1) (P40075)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Targets proteins containing a FFAT motif to endoplasmic reticulum membranes. Regulates phospholipid biosynthesis by modulating the subcellular localization of the transcriptional repressor OPI1.
Subcellular location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Nucleus membrane; Single-pass type IV membrane protein.
Interaction partners:
- Oxysterol-binding protein homolog 3
- Transcriptional repressor OPI1
- Oxysterol-binding protein homolog 2
- Oxysterol-binding protein homolog 1
- Inositol-3-phosphate synthase
- Uncharacterized protein YMR124W
- Choline-phosphate cytidylyltransferase
- Phosphatidylinositol 4-kinase STT4
- Tricalbin-1
- Increased sodium tolerance protein 2
Sequence:
MSAVEISPDVLVYKSPLTEQSTEYASISNNSDQTIAFKVKTTAPKFYCVRPNAAVVAPGETIQVQVIFLGLTEEPAADFKCRDKFLVITLPSPYDLNGKAVADVWSDLEAEFKQQAISKKIKVKYLISPDVHPAQNQNIQENKETVEPVVQDSEPKEVPAVVNEKEVPAEPETQPPVQVKKEEVPPVVQKTVPHENEKQTSNSTPAPQNQIKEAATVPAENESSSMGIFILVALLILVLGWFYR
Protein: Mas-related G-protein coupled receptor MRG (MAS-R) (MAS1-like) (P35410)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Pro-FMRFamide-related neuropeptide FF
- Angiotensin-converting enzyme
- Type-1 angiotensin II receptor
- Angiotensin-converting enzyme 2
- Angiotensinogen
- Renin
Sequence:
MVWGKICWFSQRAGWTVFAESQISLSCSLCLHSGDQEAQNPNLVSQLCGVFLQNETNETIHMQMSMAVGQQALPLNIIAPKAVLVSLCGVLLNGTVFWLLCCGATNPYMVYILHLVAADVIYLCCSAVGFLQVTLLTYHGVVFFIPDFLAILSPFSFEVCLCLLVAISTERCVCVLFPIWYRCHRPKYTSNVVCTLIWGLPFCINIVKSLFLTYWKHVKACVIFLKLSGLFHAILSLVMCVSSLTLLIRFLCCSQQQKATRVYAVVQISAPMFLLWALPLSVAPLITDFKMFVTTSYLISLFLIINSSANPIIYFFVGSLRKKRLKESLRVILQRALADKPEVGRNKKAAGIDPMEQPHSTQHVENLLPREHRVDVET
Protein: Glycosidase (EC 3.2.-.-) (Q6FSM3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Cell envelope {ECO:0000256|ARBA:ARBA00004196}. Membrane {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004589}.
Interaction partners:
Sequence:
MLYNYKRSLAVGILASVVAADSCDPLKQTNCPADKALATSFSENFTSESKWFTAEDNPGKIEYTSDGLAMSLTKRFDNPSLKSNFYIMYGKTEVIFKAGDGRGIVSSFFLQSDDLDEIDLEWIGSDDTQFQSNYFSKGNTATYDRGEFHGVNQPQKEFHNYTIDWTMEQLTWYLDGQVVRVLPNTTSQGYPQTPMYIKMGIWAGGDPSNAPGTIEWAGGETDYSLAPFTMYIKSLVVTDYSTGKEYTYGDQSGSWQSIKAVDGEINGRYQQAQEDFAKLVAGQAIESSQSSSVSPTSSSSSSASSSTSSSTSSSTSSSASSSASSSSSSSISSSSSASSSAQSSSSPIASSVSSIKSVSSSAISSSKSSQTAESKSSTSSSVKPTTQSSKTDTIMDNVTHSASTSNVAKSTVSTVAKSTESSTHSVQQSNFGVNTQVSVVSVILGFIFSIVI
Protein: Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2) (Q86Z02)
Organism: Homo sapiens (Human)
Function: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation. Phosphorylates PAGE4 at 'Thr-51' which is critical for the ability of PAGE4 to potentiate the transcriptional activator activity of JUN.
Subcellular location: Nucleus {ECO:0000269|PubMed:15701637, ECO:0000269|PubMed:16390825, ECO:0000269|PubMed:18219322, ECO:0000269|PubMed:19646965, ECO:0000269|PubMed:28289210}. Cytoplasm {ECO:0000269|PubMed:15701637, ECO:0000269|PubMed:18219322, ECO:0000269|PubMed:19646965, ECO:0000269|PubMed:28289210}. Nucleus speckle {ECO:0000269|PubMed:16390825}. Note=Predominantly nuclear. Translocates from nucleus to cytoplasm in response to stress stimuli via SENP1-mediated desumoylation. {ECO:0000269|PubMed:15701637, ECO:0000269|PubMed:18219322}.
Interaction partners:
- Cellular tumor antigen p53
- Ras association domain-containing protein 5
- Death domain-associated protein 6
Sequence:
MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
Protein: RNA-binding protein 42 (RNA-binding motif protein 42) (Q91V81)
Organism: Mus musculus (Mouse)
Function: Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:19170760}. Cytoplasm {ECO:0000269|PubMed:19170760}. Note=Upon stress response, localizes with HNRNPK in cytoplasmic aggregates of stalled translational preinitiation complexes called stress granules.
Interaction partners:
- U4/U6.U5 tri-snRNP-associated protein 1
- U1 small nuclear ribonucleoprotein A
- U4/U6 small nuclear ribonucleoprotein Prp3
- U4/U6 small nuclear ribonucleoprotein Prp31
- Pre-mRNA-processing factor 6
- Ubiquitin carboxyl-terminal hydrolase 39
- U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
- U6 snRNA-associated Sm-like protein LSm4
- U6 snRNA-associated Sm-like protein LSm5
- Small nuclear ribonucleoprotein F
Sequence:
MASAMAGAGPAPGLPVAGGPVVPGPGVGIPGKSGEERLKEMEAEMALFEQEVLGAPVTGIPTAVPAVPTVEAMQVPPAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPVGFGPADRGHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAGGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKDKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKLKRCIRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKKLGLR
Protein: Syncrip, isoform K (A0A0B4KHH8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNKFVSHNLGRDPYRTFSPEMYPLSSPLGPHGTEMAEGNGELLDDINQKADDRGDGERTEDYPKLLEYGLDKKVAGKLDEIYKTGKLAHAELDERALDALKEFPVDGALNVLGQFLESNLEHVSNKSAYLCGVMKTYRQKSRASQQGVAAPATVKGPDEDKIKKILERTGYTLDVTTGQRKYGGPPPHWEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRLMMDPMTGTNRGYAFVTFTNREAAVNAVRQLDNHEIKPGKCLKINISVPNLRLFVGNIPKSKGKDEILEEFGKLTAGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWADPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQYGKVERVKKIKDYAFIHFEDRDSAVEAMRGLNGKEIGASNIEVSLAKPPSDKKKKEEILRARERRMMQMMQARPGIVGFETLSPYRNLSPTHPSIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFSDYRQGGSFGNNVSYYDDMYRWIDGDYNYYDYPNGGGGGSGGGGGSVSGGTVLPLSAGGSQNSPMASGQRSARGSASGPSASPSLMGVGRGHGITVPRGRVVGQRGSISRLGAQTVPQAAGAAAAAGQAAAAVAQRGATGQGAPAATGGFRGVLPTRPSARGTQHVKPLQNLPVVGKRKFDGGHQNPADVKRRYPSGLIGNGGSWGSLPLPQQPLGTNGEQWYMDTFSAWS
Protein: Heat shock 70 kDa protein cognate 5 (P29845)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GrpE protein homolog, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM44
- SD19278p
- Heat shock protein 60A
- Mitochondrial import inner membrane translocase subunit TIM14
- 60 kDa heat shock protein homolog 2, mitochondrial
- 60 kDa heat shock protein homolog 1, mitochondrial
- Hsc70Cb, isoform G
- GEO10507p1
- Heat shock protein 83
Sequence:
MLRVPKFLPRLARQAGVVPSHMSGASSMFRNLPGASNGISSQLRYKSGEVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDGKVYSPSQIGAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRTLLANKETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSGEAKKEEKN
Protein: FAS1 domain-containing protein fsc1 (O94439)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for the fusion of autophagosomes with the vacuole.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:23950735}; Single-pass type I membrane protein {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:23950735}.
Interaction partners:
- Uncharacterized transcriptional regulatory protein C757.04
- Ubiquitin-like-conjugating enzyme ATG10
- Uncharacterized transcriptional regulatory protein C417.09c
Sequence:
MNLQFRLYLLFILLFISFANGKNEYEDKSTSIIDLLSSKSQFSKLIRRLQRNRLVPYLNRNKGLTLFAPLNEAFPDDSIEPNLLYYIVNTTELDRSVLRTQLKSSDGQQIALKIHYKAETGRAYDKVNNAQIVQSNWRADSGVVQVIDNIIDLPPPALEILSSEKDFSIFHRLSVAWVGEYSSVTMLVPDSSAFLNVYTNTELAYLYSMYAAEDVKTLIHQHILVNQRVYAEDVIEPKTFHYKNGISISMKFDKDQKKLFINDVSTTKYDLLTFSGAIHTVSSLINPEIISFTPAKYLIGIGAAWFSEKLSRERKSISVDKTSKRAILAPTNWAYREIIDIDYHIIENFDLPAPNKYALYVTNIKSGNSVGEDTNALVRIATGSAGEMYVNVETRSIQSENIGNVSLYVLDKDIEPPQPLLSQLILVDEISFSVRYLASLGLGDYTKVTWFLVKNSAWTQLGLVHLVLQQNLELLESVMLDYAFEGIAFYGSSDEAWASGNYTTLSNKEFLIEGVYEDSNSRNKRDLLRINNEIYEVQTRDLLVKDGVVHLVDKVKLPFSVSQKDMIIAGGRKEFLELLDKFEMLDMLDSGYPVVVPSLTGSDVNTKDSSFAERHIIDPEKRNFVISGSRLSVDSSPWISIQDYGYSELGNVYFVQNAIPTKRQNRWRITFISISGLLLSVGICVLCYKIYFKFFRNRFMNQGEREPLLAPADSDTMAGRRNSSSLSV
Protein: Uncharacterized protein (Q38EZ3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEAIYFTTKLDEVRSYYESDTKSDDDIVYAVYSLVNDAHTVSKMLLLESRFEELRRCLSVCWVALGEEHVKEDGRIVLGNLTGEDRRMIDLLLQRTLLLEQQTEEVIQKNKAQNIMSYTAEVIRSQLATLTKESGLKSGIGTANGDNKERGQGESKPPVTPPKRGSAFGRSKLMRRWGGERATPPLVTYTRFSNASSGLPYETVSSLTESDEGAQPEGSSSFSHYTLRDVSATAIHRVGNGSYSSSVSGGADVRPGAAVCVPSENFVPPVNSSELFGPNASTLGRDQRGICSGLAEASAGPSRSPSEKSSSFSSYTSALSDVWAADTGKRIARTATAMRVAVEEQYFPAGVVEGLDNAILSEVKQDSVKGPPEIPPRLSHTLTCGALVGQQDHTKRKSDAATDDGLVAFDESVSGDAPADPLRETMETADQHVETVPCLPPMQNDVSPGSSQGSVELCSGQRNDTQSTSGFLPMLTLCPKLSSEAKAHVAKVCKEYKEKMMDVNLSMEAMRRKTEEQKQLLNPKDKFVLKATNEWMRMQKTPTTSPGAAVEPSVAGQSDLPTPSKGPAEVAYKQACLSVGQRLQTSHTWRRRSSRMPSCRTVESFATDESFFSQTNTFEYPTTSSASHTGVGPLNGIRGSAGKAATDETRENVSQTDGAKARSSPTPRRKIAGVRLTDAQHQLKRLRLLSDEPFPEVHRMVIERAEKIVDLEQGGLSIGRLRSHPRSSHREGLPSNTENFPGLSLSSVQTNSLTRYGHVLSSLPSGNMHPGTGSSEHLPLLSWMKQNCGSLSAAVRKDVLGIRPSSGANLVTVVRSTDAKVTAEDLQPTILSSIDDLHRRPNWTVLNTATLSMFAPLHLAVVRIQLVLRQFIAKRELNDRKRAVEDHLARLVVRDECAIAIQRWGRWLISLQFVAVLLYRSKTYEKLSERSLNCEAPSFTDVSYELIRRFSVTGNLTTAFFTPTPEPRIRSGNLSRTGNRRVTVGCLPYFPRSTVGQAPFGLPSSSCTTMCQASVSLSRESSPVRRQREIDASRVIVKAFRKCKQSKLRVWEREMDNFLRFVTRKASAGETFKDSRCKSQRQTQKYTGDVKCSPRRGGRAEDATLFPVSPDRLLGDTYAAWEARVRKAREEGNFLTPLNSVKLSQLYSIYEQRLEVEALRRLRELEALIEAEEEQVKREELEQSLQVLQPCLRGYLARRRIAFRWKELKKGKLFSNRPARLINVSRNRTAGFRGRAERGRTVPLEGESLEFACEEEHPIPPKVDNFIQQSINRRNTLMIPITDEGRTARLRLVIMMQTCLRQKASLLSVADQYVTVCAVAIQRWWRLMTLLRKRSSDKIQGANCAI
Protein: Ras-related protein Rab-6 (Q55FK2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Protein transport. Probably involved in vesicular traffic (By similarity).
Interaction partners:
- Rab GDP dissociation inhibitor
- RIC1 C-terminal alpha solenoid region domain-containing protein
- Vps53-like domain-containing protein
- Vesicle transport through interaction with t-SNAREs homolog 1A
- Conserved oligomeric Golgi complex subunit 6
- Rab escort protein 1
- Conserved oligomeric Golgi complex subunit 8
- Intermembrane lipid transfer protein vps13B
- Vacuolar protein sorting-associated protein 54
- E set domain-containing protein
Sequence:
MESLSKYKLVFLGDQSVGKTSIITRFMYDTFDITYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAIVVYDITNKVSFTNTIKWIEDVRNERGNNVVIMLVGNKTDLADKRQVSIEEGEAKAKEYDIMFTETSAKAGFNIKALFRKVASALPGIDSNSMTKNQHEIISEVDITDGGKPALKEGDGFCSSSRC
Protein: Thioredoxin reductase (TRXR) (EC 1.8.1.9) (P0A9P4)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm.
Interaction partners:
- Thioredoxin 1
- Thioredoxin 2
- Alkyl hydroperoxide reductase C
- Selenide, water dikinase
- Cysteine desulfurase
- Putative oxidoreductase YgfK
- Thiol:disulfide interchange protein DsbC
- Glutaredoxin 1
- Probable hypoxanthine oxidase XdhD
- Putative dimethyl sulfoxide reductase chain YnfE
Sequence:
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
Protein: ATP synthase F(0) complex subunit C2, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase membrane subunit c locus 2) (ATP synthase proteolipid P2) (ATPase protein 9) (ATPase subunit c) (P56383)
Organism: Mus musculus (Mouse)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
Subcellular location: Mitochondrion membrane; Multi-pass membrane protein.
Interaction partners:
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- ATP synthase F
- ATP synthase peripheral stalk subunit d, mitochondrial
- ATP synthase peripheral stalk subunit b, mitochondrial
Sequence:
MYACSKFVSTRSLIRSTSLRSTSQLLSRPLSAVELKRPQMPTDESLSSLAVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
Protein: Spermine oxidase (A0A8I6AE29)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGRRIPKDVVEEFSDLYNEVYNLTQEFFRNGKPVNAESQNSVGVFTREKVRNRIRDDPDDTEATKRLKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAKGIPPHVIQLGKPVRCIHWDQASARPRGPEIEPRERYGHVLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP
Protein: 26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit rpn-12) (Q23449)
Organism: Caenorhabditis elegans
Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 3
- Probable 26S proteasome regulatory subunit 4
- Probable 26S proteasome regulatory subunit 6B
- Probable 26S proteasome regulatory subunit 10B
- Proteasomal ubiquitin receptor ADRM1 homolog
- 26S protease regulatory subunit 6A
- PCI domain-containing protein
- 26S proteasome regulatory subunit 7
- Proteasome subunit beta type-3
Sequence:
MSAAHKNLLAVWAKEPKDLVAVEKALNELTKVLSASSDLNDKQSALASKDLYEISVLLAILKHDFETFDDYINQMHTYYTMAPENSENKHLMTGLHLMFLLAANRLSDFHMLLEQIPQKEQTSNAYISTPVRIEQSLMEGAYNKVVLTEKNIPSPFYTIFIRIMLDTIRREIATSIEKSFKVLTAKDATVMLLFDNDEQMKKFGQERKWHLDGERYVFEIEVAQEKPVNLDTVRVATQTLFYAKQLEQIV
Protein: F420-dependent NADP reductase (EC 1.5.1.40) (F420H2:NADP oxidoreductase) (D9PVP5)
Organism: Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
Function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions.
Interaction partners:
- 5,10-methylenetetrahydromethanopterin reductase
- Coenzyme F420 hydrogenase subunit beta
- F420-non-reducing hydrogenase subunit G
- Predicted 3-hexulose-6-phosphate isomerase
- Predicted sugar phosphate isomerase / epimerase
- Coenzyme F420:L-glutamate ligase
- Nitrogenase iron protein 1
- Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE
- 2-phospho-L-lactate transferase
- H
Sequence:
MKIAVLGGTGDQGLGLALRLALAGEEVIIGSRDAEKAVSAAQKVLEIAERDDLKVKGATNAEAAEEAEVAILTVPLQAQMATLGSVKEAIKGKVLIDATVPIDSCLGGSAVRYIDLWDGSAAERAARFLEDQGTRVAAAFNNISASALLDITGPVDCDCLIASDHRDALDLASELAEKIDGVRAIDCGGLENARVIEKITPLLINLNIKNRIRNAGIRITNLPE