wanglab/gogpt-training-data huggingface dataset:
Protein: FKBP-type peptidyl-prolyl cis-trans isomerase (Stress-enhanced protein 4) (Q9LHH3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Starch synthase 3, chloroplastic/amyloplastic
- Ornithine transcarbamylase, chloroplastic
- starch synthase
- Alpha-glucan phosphorylase 1
- Alpha-glucan phosphorylase 2, cytosolic
- Peptidyl-prolyl cis-trans isomerase CYP18-1
- Thiamine phosphate phosphatase-like protein
- Putative clathrin assembly protein At1g33340
- non-specific serine/threonine protein kinase
- Ribosome biogenesis protein NOP53
Sequence:
MAITPLRITNPFPSLRFIPAGKPNALRIFTVHATDVESTEDTQPDPETTQSESGTDPDQFESRLSNIRLRYRSGTGKKAEVRKSKKGSSGSPSKGTGIYLPPVSLKEAVSGGLKVEPGFSPFSERINGRIAGLGLTALLLVELATGKSVLNYHTPSVVFLQIYFVAAVSAMFVKIEKEKVSVWPKD
Protein: Kelch domain-containing protein 9 (Kelch/ankyrin repeat-containing cyclin A1-interacting protein) (Q8NEP7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQEGCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKEEPPVAPHLMEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI
Protein: Protein GET4 (AtGET4) (Guided entry of tail-anchored proteins 4 homolog) (Q6GKV1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the regulation of root hair growth.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:28096354}.
Interaction partners:
- Ubiquitin-like superfamily protein
- Ubiquitin-like superfamily protein
- AT5g42220/K5J14_2
- At1g77230
- Tetratricopeptide repeat
- ATPase GET3A
- ATPase GET3C
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- ATPase GET3D, chloroplastic
- Ubiquitin receptor RAD23b
Sequence:
MSRERIKRELPPVQEHIDKLRKVIEEGNYYGALQMYKSISARYVTAQRFSEALDILFSGACIELEHGLVNCGADLAILFVDTLVKAKSPCNDETLDRIRCIFKLFPRVPVPPHLVDVSDDEDVQNLQESLGEARSRVENLTSFLRAAIKWSAEFGGPRTGYPELHAMLGDYLYTECPELDMVRISRHFVRAEDPEKFASMLVNFMGRCYPGEDDLAIARAVLMYLSMGNMKDANFMMDEIKKQAETKNPELSESDLIQFISYLLETLQRDALPLFNMLRVKYKSSIDRDQLLNELLDEIAERFYGVQRKNPLQGMFGDIFKMMG
Protein: Transcription factor TGA4 (Ocs element-binding factor 4) (OBF4) (bZIP transcription factor 57) (AtbZIP57) (Q39162)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. May be involved in the induction of the systemic acquired resistance (SAR) via its interaction with NPR1. Could also bind to the Hex-motif (5'-TGACGTGG-3') another cis-acting element found in plant histone promoters.
Subcellular location: Nucleus.
Interaction partners:
- Regulatory protein NPR1
- Dof zinc finger protein DOF3.4
- Ethylene-responsive transcription factor RAP2-3
- Dof zinc finger protein DOF3.6
- LOB domain-containing protein 37
- High-affinity nitrate transporter 2.2
- Basic leucine zipper 8
- High-affinity nitrate transporter 2.1
- Protein NLP7
- Protein NRT1/ PTR FAMILY 6.3
Sequence:
MNTTSTHFVPPRRFEVYEPLNQIGMWEESFKNNGDMYTPGSIIIPTNEKPDSLSEDTSHGTEGTPHKFDQEASTSRHPDKIQRRLAQNREAARKSRLRKKAYVQQLETSRLKLIHLEQELDRARQQGFYVGNGVDTNALSFSDNMSSGIVAFEMEYGHWVEEQNRQICELRTVLHGQVSDIELRSLVENAMKHYFQLFRMKSAAAKIDVFYVMSGMWKTSAERFFLWIGGFRPSELLKVLLPHFDPLTDQQLLDVCNLRQSCQQAEDALSQGMEKLQHTLAESVAAGKLGEGSYIPQMTCAMERLEALVSFVNQADHLRHETLQQMHRILTTRQAARGLLALGEYFQRLRALSSSWAARQREPT
Protein: Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358) (Q9EPU5)
Organism: Mus musculus (Mouse)
Function: Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Plays a role in neuronal apoptosis, including apoptosis in response to amyloid peptides derived from APP, and is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21; this triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. Negatively regulates T-cell responses and the release of cytokines such as IL4, IL5, IL10, IL13 and IFNG by Th2 cells. Negatively regulates the production of IgG, IgM and IgM in response to antigens. May inhibit the activation of JNK in response to T-cell stimulation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12515813}; Single-pass type I membrane protein {ECO:0000269|PubMed:12515813}. Note=Endocytosed following oxidation in response to reactive oxygen species (ROS). {ECO:0000250|UniProtKB:O75509}.
Interaction partners:
- Amyloid-beta precursor protein
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- Caspase-6
- Tumor necrosis factor receptor superfamily, member 25
Sequence:
MGTRASSITALASCSRTAGQVGATMVAGSLLLLGFLSTITAQPEQKTLSLPGTYRHVDRTTGQVLTCDKCPAGTYVSEHCTNMSLRVCSSCPAGTFTRHENGIERCHDCSQPCPWPMIERLPCAALTDRECICPPGMYQSNGTCAPHTVCPVGWGVRKKGTENEDVRCKQCARGTFSDVPSSVMKCKAHTDCLGQNLEVVKPGTKETDNVCGMRLFFSSTNPPSSGTVTFSHPEHMESHDVPSSTYEPQGMNSTDSNSTASVRTKVPSGIEEGTVPDNTSSTSGKEGTNRTLPNPPQVTHQQAPHHRHILKLLPSSMEATGEKSSTAIKAPKRGHPRQNAHKHFDINEHLPWMIVLFLLLVLVLIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSLTPTQNREKWIYYRNGHGIDILKLVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLISALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPMPSPNVKLENSTLLTVEPSPLDKNKCFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIFDDMLHILNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL
Protein: HBS1-like protein (D9YZV0)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYEDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
Protein: 17-beta-hydroxysteroid dehydrogenase type 3 (17-beta-HSD 3) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 2) (Testicular 17-beta-hydroxysteroid dehydrogenase) (Testosterone 17-beta-dehydrogenase 3) (EC 1.1.1.64) (P37058)
Organism: Homo sapiens (Human)
Function: Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16216911, ECO:0000269|PubMed:26545797}.
Interaction partners:
- 17-beta-hydroxysteroid dehydrogenase type 2
- Steroid 17-alpha-hydroxylase/17,20 lyase
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
- Aldo-keto reductase family 1 member C3
- 17-beta-hydroxysteroid dehydrogenase type 1
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1
- Aromatase
- Cytochrome P450 11B1, mitochondrial
Sequence:
MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR
Protein: Baeyer-Villiger monooxygenase (BVMO) (EC 1.14.13.-) (Q88J44)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor. Preferentially converts short-chain aliphatic ketones like 2-decanone, 3-decanone and 4-decanone. Some acyclic ketones are converted not only to the alkylacetates, but also methyl- and ethylesters are obtained, indicating insertion of oxygen on both sides of the keto group.
Interaction partners:
- Hydrolase, alpha/beta fold family
- Xenobiotic reductase B
- Uric acid permease
- Long-chain fatty acid transporter
Sequence:
MSSHTALPVEPLDVLIMGAGVSGIGAAAYLRRNQPNKTFAILESRERMGGTWDLFRYPGIRSDSDLYTFGFDFKPWTKAKSLADAADILEYLSEAIDEHQLAPFIQYQQKVISANWQSDKGLWSVRVEDGRTAQIRTVECRWLFSAGGYYRYDQGFSPRFEGSEQFKGQIIHPQHWPEDLDYTGKRVVVIGSGATAVTLIPAMADKVASITMLQRTPSYIINQPANDGVAAFLRKVLPAQTAYSLTRYKNAKITLAFWGFCQRFPKLSKKLLLWLTRKELPKDYPVDVHFNPPYNPWDQRLCSVPEGDLFKAISAGNADIVTDHIERFTEHGVLLKSGKMLKADIIVTATGLNVQLFGGITLHKDGKPVVLSETLAYKGMMLSGVPNFAFAVGYTNSSWTLKVCLLCDHFCRLLGLMEREGYNVCEPKAPEGVETRPLLDFGAGYVQRALDSMPRQGPREPWVMSMDYFRDVKLLRRGAVTDKCLKFTAVPNAPLHADVQLQQQGSRR
Protein: Alpha-2B adrenergic receptor (Alpha-2B adrenoreceptor) (A0A060Y7B7)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Ig-like domain-containing protein
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit gamma
- Endothelin-3
- Neuropeptide Y
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit gamma
- Guanine nucleotide-binding protein subunit alpha-13
- Guanine nucleotide-binding protein subunit alpha-13
- Uncharacterized protein
Sequence:
MAAAPKVTCLSAPGVNVITNLNLSVTTGSAPYYNQTALRIPPYSREATALFAMAITLMMILTIVGNILVIIAVLTSRSLHGPQNLFLVSLAAADILVATLIIPFSLANELQGYWAFRSLWCEIYLALDVFFCTSSIAHLCAISLDRYLSISRPVSYGIQRTPARIKAAIVVVWLLSAVISFPPLLSLDKSKGGVEVCELNNERWYILYSTIGSFFAPCLIMIGVYIRIYQIAKQHTRCLPGEKPNPNKSPGNMSSNPPTNPTPPSPGPAKSQPQTSLPNPVPTSPQPTSPTVALSLTLLSPDSQHEETHRQGEIQEEKHRDTPNDDSFSSGSEAETRGRGKGGRGGGKGTVKNNGGSKSGGAPLSSLTSHEAKNTPQATPMSRRRAMVNREKRFTFVLAVVIGVFVICWFPFFFSYSLKAIFPETCLVPAPLFTFFFWIGYCNSCLNPVIYTIFNQDFRKAFKKILCRDTKGTFF
Protein: Trypsin Tyr p 3.0101 (EC 3.4.21.4) (Mite group 3 allergen Tyr p 3) (allergen Tyr p 3.0101) (C6ZDB5)
Organism: Tyrophagus putrescentiae (Mold mite) (Acarus putrescentiae)
Function: Digests TAMe (p-toluene arginine methyl ester), but not ethyl N-benzoyl-L-tyrosinate (BTEE).
Subcellular location: Secreted {ECO:0000269|PubMed:19339798}.
Interaction partners:
Sequence:
MKILLFLCFLVSVAFAKPPTIQLKSNTKSQNGFIVGGTEAVDGDAPHQVSLQHTSHFCGGSIISERWILTAAHCIDADDLSNPGGMSVRYNTLNLKSGTLVKVKSIKVHEQYSNVTSDNDIALLETVASMNLNQTNAVAAKLPAKGNDPQDGDLFLSGWGTLHSGDTTIPTNLQKVTVPLTNRSVCAEAYTGIVNITENMFCAGKMGIGGVDSCQGDSGGGAMLNKELVGVVSFGVGCGDPKYPGVYTRVSQYLDWIELSAKSSATTLVAVNITLFLTLFIGAIW
Protein: Hemoglobin cathodic subunit beta (Hemoglobin cathodic beta chain) (B3EWR8)
Organism: Ophisurus serpens (Serpent eel) (Muraena serpens)
Function: Involved in oxygen transport from the gills to various peripheral tissues.
Interaction partners:
Sequence:
VQWSSSERSVISGLWAKVNAAEVGPQALARLLVLYPWTQRYFGKFGDLSSNAALMGNANVAKHGKDLLLADLKAVKNMDNVKALYAKXXXXXXXELNVDPDNFTLLGDCLTIVLAMKFGADFTPVDQAVWQKFVAVVVSGLSKQYF
Protein: Transducin-like enhancer protein 3-A (Groucho-related protein grg2) (Protein groucho-2) (O13166)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q04726}.
Interaction partners:
- Lymphoid enhancer-binding factor 1
- Transcription factor 7-like 2
- Transcription factor 7.
- Transcription factor 7-like 1-A
- Histone deacetylase 1
- Zinc finger protein 703
- Recombination signal-binding protein for immunoglobulin kappa J region a.
- Recombination signal-binding protein for immunoglobulin kappa J region-like.
- Recombination signal-binding protein for immunoglobulin kappa J region b
- ETS domain-containing protein Elk-4 isoform 1
Sequence:
MYPQGRHPAPQTPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYIKLANEKTEMQRHYIMYYEMSYGLNIEMHKQTEIAKRLNAILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQLQAQHLSHTHGPVALTPPHPSGLQPPGIPPVTGSGSGLLALGALGSQPHLPAKDEKNHHDLEHRESTNNSISPSDSLRTTSEKHRGSSDYSLDSKKRKVEDKDSMSRYDSDGDKSDDLVVDVSNEDPATPRGSPAHSPPENGIDKPRPAKKDTPRRPASVASSGSTPSSKTKPPEHNDKSSTPGLKSKAPTPRNDAPTPGTSTTPGLRPILGKPPMEALAAPALRTPLTCPTPFAMMSHHEMNGSLTNPGVYAGLHISPQMSAAAAAAYGRSPMAGFEPPHMRAPGLPASLTSISGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPVSQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFASQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWSTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY
Protein: Conserved protein (P95148)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable fatty oxidation protein FadB
- Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3
- 3-hydroxybutyryl-CoA dehydrogenase
- Acetyl-coenzyme A synthetase
- Steroid 3-ketoacyl-CoA thiolase
- Probable beta-ketoacyl CoA thiolase FadA3
- Malate synthase G
- Probable acetyl-CoA acyltransferase FadA2
- 2-isopropylmalate synthase
- Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit B
Sequence:
MPVDPRTPVLIGYGQVNHRGDIDAEKQSIEPVDLMAAAARKAADSTVLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSLVNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPDMAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGELWARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVDQGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAIRIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLTVTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFGVYGTEPPSEFRWEDMQPAVDREPTGDGLVEWEGIGTVEAWTTPVNRDGQPEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTATLR
Protein: Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) (P23468)
Organism: Homo sapiens (Human)
Function: Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Interleukin-1 receptor accessory protein-like 1
- Interleukin-1 receptor accessory protein
- SLIT and NTRK-like protein 1
- Liprin-alpha-1
- Liprin-alpha-3
- SLIT and NTRK-like protein 2
- SLIT and NTRK-like protein 3
- Neuroligin-3
- Leucine-rich repeat and fibronectin type-III domain-containing protein 5
- X-linked interleukin-1 receptor accessory protein-like 2
Sequence:
MVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT
Protein: Uncharacterized protein YahO (P75694)
Organism: Escherichia coli (strain K12)
Subcellular location: Periplasm {ECO:0000305}.
Interaction partners:
- Uncharacterized protein YbgS
- Uncharacterized protein YccJ
- UPF0337 protein YjbJ
- Uncharacterized protein YgaM
Sequence:
MKIISKMLVGALALAVTNVYAAELMTKAEFEKVESQYEKIGDISTSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK
Protein: Gibberellin-regulated protein 3 (GAST1 protein homolog 3) (P46687)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation.
Subcellular location: Secreted.
Interaction partners:
- Glycine-rich cell wall protein-like protein
Sequence:
MAIFRSTLVLLLILFCLTTFELHVHAAEDSQVGEGVVKIDCGGRCKGRCSKSSRPNLCLRACNSCCYRCNCVPPGTAGNHHLCPCYASITTRGGRLKCP
Protein: Keratin, type I cytoskeletal 28 (Cytokeratin-28) (CK-28) (Keratin-25D) (K25D) (Keratin-28) (K28) (Type I inner root sheath-specific keratin-K25irs4) (Q7Z3Y7)
Organism: Homo sapiens (Human)
Function: Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:A6BLY7}.
Interaction partners:
Sequence:
MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVPF
Protein: C4-dicarboxylate transporter DcuA (P0ABN5)
Organism: Escherichia coli (strain K12)
Function: Responsible for the transport of C4-dicarboxylates during aerobic and anaerobic growth. Required for the uptake of L-aspartate as a nitrogen source during aerobic growth. The uptake of L-aspartate in aerobic conditions is coupled to the excretion of fumarate, resulting in the net uptake of nitrogen without carbon uptake. In addition, during anaerobic growth, catalyzes the uptake of fumarate, malate or aspartate coupled to the export of succinate. Can also catalyze the uptake (without exchange) of fumarate. May play a a general role in anaerobic C4-dicarboxylate transport.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:9733683}; Multi-pass membrane protein {ECO:0000269|PubMed:9733683}.
Interaction partners:
- Aspartate ammonia-lyase
Sequence:
MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML
Protein: Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform X2 (Multifunctional protein ADE2 (EC 4.1.1.21)) (Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase) (Q7ZUN6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSTATELKLGQKLNEGKTKQIFEILDEPGHVLVQSKDQITAGNAVRKDQMEGKAAIANKTTSCVFKLLQDAGLKTAFVRQHSDTAFVASRCEMIPIEWVCRRIATGSFLKRNPGVKEGYRFTPLKMEMFFKDDANNDPQWSEEQLLAAGFDLAGLTIGRCEVDIMSKSTVAIFEVLEKAWATQDCTLVDMKIEFGVNVTTKEIVLADVIDNDSWRLWPAGDRSQQKDKQVYRDLKEVTPEAMQMVKRNFEWVAERVKLLLESQARGRVVVMMGSTSDVAHCEKIRKACASYGIPCHLRVNSAHKGPDETLRIKAEYEGDGEPTIFVAVAGRSNGLGPVMSGNTAYPVINCPPVTPDWGAQDIWSSLRMPSGLGCSTVLSPEAAAQFAAQILGLNNHLIWAKLRASMLNTWVSLKQADKKMQDCSL
Protein: Zcf10p (A0A1D8PHW6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
Sequence:
MSESEDPNKKRKRIRRACDFCRSKKAKCDGKSPVCSNCFANKEECIYSQPVKRRGLPTGYTHDLEKKVRLFQGLIARLCEDKYVQSRLQTILNDESLVDDLVELEKSWNSNSISELFDQVASQSNSKNNIAKLATHKPTPVQSDSTPVSTLDGNPPLTTSQCQVCQKSQDRKFRKAHTPDPSQTISASPSTSQTATAATAATAAATVAADNAINPVIGSDRPTSIYPSTPSPFVSDSAFFLNYDVFQFISDEIEGVENPENWEPVALQYHGLSSIISGFTNKVVQQYNSKLNNVFKNPFRVGSIFNISSFAINASMTNKFQMPKEIFQFPINIRELVDIYFQVHQCYIPMLDRVSLIRHVNYLQSLPEHKRGSMDGNILALVWAVVALGEFSSIGGSVKKSSIFAKNAIMALENSFTTTIETIQAMITLGLVYYHLGQWDFSWVLISSGTRMAIDVRLMRNASDEDNPRVQSSASLNNINRQRTWATVYFVNTLLCARMGRSPVVRASDWPVPEINNDGWEEWSPWECYYAPNEIKLESGKFLSTFNETLKGVYILNLAITSTIDTSRGYYQNGEVKSEFKINYDDRQNSNNMTLEMFNDMIDAWSNQLPESFKDDQSNTGLKSPSTTILVLLRGLIWCVLAVRLSSLKGNSEIKDQIIQFRNQKYTEAIVAMKRCINENSENIWKHYFLFDYFLIMTFNFPYMMNFESEFMKYAHIQEMKNILVSCSETSIPCSICWDLLKIMNNGTKQRESSKLHDTPKAQESPTIANLLNDQADTEAVGPQPPTEVQPVASVPPMAPVAPNSSLTSVAPAPESAPAQVAAPPLVMAPAAPPISSSGNAPYISNDKNWVNQFGPPTTMLQDLHQVQSQPIYSNSNFHQQHKYYPHQISLEEPTSSLLQVNQIKQENTTSQPNNHNPNVK
Protein: Protein translocase subunit SecE (P9WGN7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular location: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00422}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00422}.
Interaction partners:
- Probable protein-export membrane protein SecG
- Protein translocase subunit SecY
- Transcription termination/antitermination protein NusG
- Large ribosomal subunit protein uL11
- Protein translocase subunit SecA 1
- Protein translocase subunit SecA 2
- Signal recognition particle receptor FtsY
- Large ribosomal subunit protein uL1
- Sec translocon accessory complex subunit YajC
- Signal recognition particle protein
Sequence:
MSDEGDVADEAVADGAENADSRGSGGRTALVTKPVVRPQRPTGKRSRSRAAGADADVDVEEPSTAASEATGVAKDDSTTKAVSKAARAKKASKPKARSVNPIAFVYNYLKQVVAEMRKVIWPNRKQMLTYTSVVLAFLAFMVALVAGADLGLTKLVMLVFG
Protein: Protein kinase superfamily protein (Somatic embryogenesis receptor-like kinase-like protein) (Q67YR4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Spectrin beta chain, brain
- Protein C2-DOMAIN ABA-RELATED 4
Sequence:
MDDRLRLSRRIRFLLLAWLRRSRSGRIEFIRRFGYKEIIKATEGFRKVIYTNYHGSAYRAKFKGGEVALVKELTALDLGRERFDEEVQLLGRLRHRHLLTLRGFCIGRKRLLVFDNIENGSLKEHLNDPLKTPLNWKTRIQIAIGVAAALEYLLVFSSNDAQIYDVSVNSCNIMLDENFTPKISDIRVNRHPKNHPKATHDSCSEGSCADEECGNVIFQLGVLMLELITGQSSDRQGNDLIEWVQDSCIANSIDKMIDPDLGNNYSSRELQKVLAVARLCIKTRYEPPSFSITHVYRYLQKKIDVAT