wanglab/gogpt-training-data huggingface dataset:
Protein: Dicarboxylate transporter 2.2, chloroplastic (AtpDCT2) (Q9FMF8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the transport of dicarboxylate compounds.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- ADP,ATP carrier protein 2, chloroplastic
- AT5g24690/MXC17_8)
- Probable polyamine transporter At3g19553
- Sodium/proton antiporter 1
- Plastidal glycolate/glycerate translocator 1, chloroplastic
- Protein CLT2, chloroplastic
- Keratin-associated protein, putative
- D-xylose-proton symporter-like 3
- Uncharacterized protein At5g13720)
- Inorganic pyrophosphatase 2
Sequence:
MESLALRSISLSASYLSLHRSSSKSFALLPPSISVHTSPTLRSLSISSPRFTLRATASSLPEEQNKPQPPPPSPPQPQGAKLIPLAISVSIGLIVRFLIPRPEQVTSQGWQLLSIFLFTISGLVLGPLPVGAWAFIGLTASIVTKTLPFSTAFAAFTNELIWLIAISFFFARGFIKTGLGDRIATYFVKWLGKSTLGLSYGLAFCETLMGLIMPSTMARAGGVFLPVIKSLAISAGSYPGDPSSRKLGSFLIQTQLQCSGASGAILLTSAAQNLLCLKLAREVGVVISNPWITWFKVASVPAFVSLLCTPLIIYKLYPPELKHTPEAPAAAAKKLERLGPITKNEWIMLGAMAFTVSLWVFGEAIGIASVVSAMIGLSTLLLLGVINWDDCLSDKSAWDSLTWFAVLIGMAGQLTNLGVVAWMSDCVAKLLQSLSLTWPASFIILQACYLLIHYLFASQTGHAGALYPPFLAMQIAAGVPGVLAALCLAFNNNLSGALAHYSGGPAALYYGAGYVDLRDMFRVGFVMALVQAIIWGGVGSFWWKFLGLY
Protein: Nuclear factor of activated T-cells calcineurin-dependent 1 (Nuclear factor of activated T-cells, cytoplasmic 1) (Q19AW4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKSAEEDAYCYNQNTSISIPLGNPCPPSQYHNLQTSPSLSISISQPSSFPQDDMSSVGYFQTSGPRSNGAPTLESPRIEITAYGQFPEDEVEDNSVPVTKRVNSIVTLTLPSVDGYRDPTCLSPASSVSSRSCHSDASSYESGFSYNYDNSPQNSPWQSPCVSPKGSSSLQSCTLGASPRHSPSGSPRTSITDDNWIGNRGSRPNSPCGGKRKYSFNGGPSHKYHPYSPNQSPGPSPQTSPRLSVTEDSWLPNTNQYTNSAIVAAINALTTDGLTDLAEGIPLKSRKTSLEHSASMNLKVEPGGDETGSLELCQDDFSSARLPFKKETYCSGFLDVPQHPYWSKPKPYISPSLPALDWQLPSSSGPYSLQIDVQPKSHHRAHYETEGSRGAVKALAGGHPVVQLHGYMESEPLTLQLFIGTADDRLLRPHAFYQVHRITGKTVSTPSHEVLQSNTKVLEIPLLPESNMRAIIDCAGILKLRNSDIELRKGETDIGRKNTRVRMVFRVHINQPNGRTVSLQVASNPIECSQRSAQELPLVDKQSMESCAASGGEQMLLSGHNFQPDSKVVFVERAQDGHHIWEMEAKVNRESSKSVALLVDVPPYRNQRISNPVQVNFYVCNGKRKRSQYQRFTYLPTNVPTIKTEPHDDYDLPQVCAPLHPARLALHPKPYYSPPAMTPLMPTELGPCVTGPFASSPQRLVAKPISLSCSSSPSTSPKLQDLSPPHLSTKCLSAGSNLGPQSPTVPHVSTIQPTPGRYQQSILYPTGSNASSPGSHPSTPNSAPELPFTPSLTQPQATNEASALTAQITKGPVRSGSSPLIQKEADPPSMLAVSIKQEPQELDQMYLDDVNEIIRNDLSSISVHSHA
Protein: Paired-box containing protein Pax-2 (Q9PTX1)
Organism: Gallus gallus (Chicken)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- LIM/homeobox protein Lhx1
- Protein phosphatase EYA1
- Homeodomain transcription factor
- Homeobox protein GBX-2
- LIM/homeobox protein LMX-1.2
- Homeobox protein engrailed-1
- Uncharacterized protein.
- SIX homeobox 1
- Insulin gene enhancer protein ISL-1
- Sine oculis-related homeobox 2 homolog
Sequence:
MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAAAAYDRH
Protein: Chitinase-like mite allergen Der p 18.0101 (Allergen Der p 18) (Chitinase-like house dust mite allergen Der p 18) (Group 18 allergen protein) (allergen Der p 18.0101) (Q4JK71)
Organism: Dermatophagoides pteronyssinus (European house dust mite)
Function: Probably a non-catalytic chitinase-like protein, which binds to insoluble chitin and enhances the activity of the catalytic chitinases. Has weak chitin-binding activity.
Subcellular location: Secreted {ECO:0000269|PubMed:27548813}.
Interaction partners:
Sequence:
MTRLSFTVLIFLAAYFGSNIRPNVATLDPKTVCYYESWVHWRQGDGKMDPEDIDTSLCSHIVYSYFGIDASSHEIKLLDQYLMITLHDMEHFTKHKGNAKAMIAVGGASMSDQFSKTAAVEHYRETFVVSTIDLMTKYGFDGVMIDWSGMQAKDSDNFVKLLDKFDEKFAQTSFVMGVTLPATIASYDNYNIPAISNYVDFMNVLTLDYDGPWAYTVGHASALPEQLKTLEAYNKRGAPRHKMVMAVPFFARTWILEKMDKQDVGDKASGPGPKGQFTQTPGFLSYNELCVQIQAETNAFSITRDHDNTAIYAVYVHDNHAEWISFEDRHTLGDKARNITEQGYGGMSVYTLSNEDVHGVCGDKNPLLHAINSNYFRGIVTEPTVVTVTPVTHTTEHVTDIPGVFHCHQEGFFRDKTYCAKYYECKKGDFGLEQTVHHCPNHSQAFDEVSRTCVDHAKIPGC
Protein: UPF0674 endoplasmic reticulum membrane protein YNR021W (P53723)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:14562095}; Single-pass membrane protein {ECO:0000305|PubMed:14562095}.
Interaction partners:
- Protein transport protein SSS1
- Protein transport protein SEC61
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL16
Sequence:
MSSSIFGPLTGFLERVNSLNAPYQALSYDEQKAMTIWQRVKFYNWTFELCALGVLFLVYAFYKFGNSVNLKRGNQIFQSLHSFLANDLKFSRVGFNINDSKIFTVEHQNTWFSSFATGRSAIKSINLNLHLVARSNPFSMCLEYLLGFFFASLKSKQLEEFMEIVIRPNGILVTSESAHPNKNAHEILTKFRFVTSIVNKEFMNQARTENYFLSIAHTSENDKLPNNFVYMSDVNQLSGFMFHYSKPYEVLSQAGNLLKYISFTDLPVNPPRDDKEWESSIEPKAIIRCAVPQNENELKLLNQIISLVVEIYDGFTQDLVQQSPNLFITNDILKRTTNLRQQELNKIKKFMKETELELAKEKKLELEKAKRRQLKASGQQEKVDQKMKEKRERRLKNKQRTRFQ
Protein: DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Protein P1) (P10479)
Organism: Enterobacteria phage PRD1 (Bacteriophage PRD1)
Function: Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction for proofreading purpose.
Interaction partners:
Sequence:
MPRRSRKKVEYKIAAFDFETDPFKHDRIPKPFSWGFYNGEIYKDYWGDDCIEQFIYWLDTIEEPHVIYAHNGGKFDFLFLMKYFRGKLKIVNGRILEVEHGIHKFRDSYAILPVPLAASDEKIEIDYGKMERETREQHKAEILEYLKGDCVTLHKMVSLFIAEFGMRLTIGGTAMNELKQFHPYDPVRKGFDEAMRPFYFGGRCQAFEKGIIEDDIKVYDVNSMYPHAMRNFRHPFSDEFYEANEITEETYFIEWEGENNGAVPVRTKTGLDFNQRSGIFHTSIHEWRAGIDTGTIKPNRIIRTINFTETTTFGAFIDHFFSKRDAAKKAGDLFHNIFYKLILNSSYGKFAQNPENYKEWCITEGGIYLEGYDGEGCEVQEHLDYILWGRPAEMFNYFNVAVAASITGAARSVLLRALAQAERPLYCDTDSIICRDLKNVPLDAYQLGAWDLEATGDKIAIAGKKLYALYAGDNCVKIASKGASLVPRDIGFLMPPDMEPKAAKKVAQQKAKNIGGEKILKVANGGVYDFVNDAPSFKLNGNVQFIKRTIKGT
Protein: Protein Wnt-6 (XWnt-6) (P31287)
Organism: Xenopus laevis (African clawed frog)
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
Sequence:
QECKCHGLSGSCTFTTCWKKMPHFREVGDRLLERFNGAFKVMGGNDGKTIIPVGHNIKPPDKQDLIYSAESPDFCQANRKTGSPGTRGRVCNSTALDVGGCDLLCCGRGQREETVVVEENCLCRFHWCC
Protein: 3-ketoacyl-CoA ketothiolase (Kat1), putative (AFU_orthologue AFUA_1G12650) (Q5BEI0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Uncharacterized protein
- Hydroxymethylglutaryl-CoA synthase
- 3-hydroxybutyryl-CoA dehydrogenase, putative
- Peroxisomal hydratase-dehydrogenase-epimerase
- Peroxin-7
- Enoyl-CoA hydratase/isomerase family protein
- Probable enoyl-CoA hydratase, mitochondrial
- 3-hydroxyacyl-CoA dehydrogenase, putative
Sequence:
MATERLNSILSHLRPGNKGVAAITQKNPDDVVITLSLRTPLTKARKGGFKDTELDYLVYALLKEVIAKSQIDPNLIEDVCLGNVNDGKAAYLVRAASLAAGIPHTAGASSVNRFCSSGLKAVQDIANQISLGAIDIGVAVGAEIMSAGGDRLNKPFNEEVLKNQEAADCMQPMGQTSENVGKDFNISRAQQDVYAAESFRRAEVAQKAGWFDDEIVPITTRVKDPKTGEERSVTLTKDDGVRYGTTVESLSKIRPAFPQFGDKSTGGNSSQVTDGAAAVLLMRRSKAIELGQPILAKFVGATVAGVPPRVMGIGPTAAIPKLLSKFNLDKNDVDIYEINEAFASMAVYCVEKLGLDHAKVNPRGGAIALGHPLGATGARQIATILSEARRTKAKVLVTSMCIGTGQGMAGLFVNEQV
Protein: Glutathione hydrolase light chain 3 (Gamma-glutamyltransferase light chain 3) (B5MD39)
Organism: Homo sapiens (Human)
Interaction partners:
- Glutathione hydrolase 6
- N
- Gamma-glutamylcyclotransferase
Sequence:
MTSEFFAAQLRSQISDHTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVCSPVSGILFNNEWTTSALPAFTNEFGAPPSPANFIQPGKQPLLSMCPTIMVGQDGQVRMVVGAAGGTQITTDTALAIIYNLWFGYDVKRAVEEPRLHNKLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY
Protein: GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I) (Q05915)
Organism: Mus musculus (Mouse)
Function: May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis. May modify pain sensitivity and persistence.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P30793}. Nucleus {ECO:0000250|UniProtKB:P30793}.
Interaction partners:
- GTP cyclohydrolase 1 feedback regulatory protein
- 6-pyruvoyl tetrahydrobiopterin synthase
- Vacuolar protein sorting-associated protein VTA1 homolog
- Inosine triphosphate pyrophosphatase
- Molybdenum cofactor biosynthesis protein 1
- Sepiapterin reductase
- Intestinal-type alkaline phosphatase
- Alkaline phosphatase, germ cell type
- Alkaline phosphatase, tissue-nonspecific isozyme
- Alkaline phosphatase
Sequence:
MEKPRGVRCTNGFSERELPRPGASPPAEKSRPPEAKGAQPADAWKAGRHRSEEENQVNLPKLAAAYSSILLSLGEDPQRQGLLKTPWRAATAMQYFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGRVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS
Protein: ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL-6-interacting protein 6) (Aip-6) (Q8BH07)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus inner membrane {ECO:0000269|PubMed:31142202}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MSFVESWRFAGARRRRQVTPGPATRPGYSDYTQGDSWGEGEGDEDEGCDQVARDLRAEFSARASSETKRAPLLPRVGDGSPVLPDKRNGIFPATAAKRTQARRWPIQALSILCSLLFAVLLAFLLAIAYMIVKELHAENLKNEDDIHTGLLGFWSLLIISLTAGLSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGIVAALTVAWCLM
Protein: 2'-5'-oligoadenylate synthase 1A ((2-5')oligo(A) synthase 1A) (2-5A synthase 1A) (EC 2.7.7.84) (Q05961)
Organism: Rattus norvegicus (Rat)
Function: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P11928}. Mitochondrion {ECO:0000250|UniProtKB:P00973}. Nucleus {ECO:0000250|UniProtKB:P00973}. Microsome {ECO:0000250|UniProtKB:P00973}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P00973}. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions. {ECO:0000250|UniProtKB:P00973}.
Interaction partners:
- Ubiquitin-like protein ISG15
- Interferon regulatory factor 7.
- Interferon-induced GTP-binding protein Mx1
- Interferon-induced GTP-binding protein Mx3
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- Interferon-induced protein 44
- Interferon-induced protein with tetratricopeptide repeats 1
- Interferon-induced, double-stranded RNA-activated protein kinase
- Interferon-induced protein with tetratricopeptide repeats 3
- Ubl carboxyl-terminal hydrolase 18
Sequence:
MEQELRSTPSWKLDKFIEVYLLPNTSFRDDVKSAINVLCDFLKERCFRDTVHPVRVSKVVKGGSSGKGTTLKGKSDADLVVFLNNFTSFEDQLNRRGEFIKEIKKQLYEVQREKHFRVKFEVQSSWWPNPRALSFKLSAPHLQQEVEFDVLPAYDVLGHVSLYSNPDPKIYTILISECISLGKDGEFSTCFTELQRNFLKQRPTKLKSLIRLVKHWYQLCKEKLGKPLPPQYALELLTVYAWERGNGITEFNTAQGFRTILELVTKYQQLRIYWTKYYDFQHPDVSKYLHRQLRKSRPVILDPADPTGNVAGGNQEGWRRLASEARLWLQYPCFMNRGGSPVSSWEVPVDEAWSCILL
Protein: Sp5 protein (Sp5 transcription factor a) (Transcription factor Sp5a) (B0S6I8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAAVAVLRNDTLQAFLQDRTPNSSPENSKHSPLALLAATCNRIGHHHGSTPTDFIQVPYDTTLGSPSRIFHPWSNEANHQSTLSSNPSFGLSSKSHLQSSYASHHELPLTPPADPTYPYDFSPVKMLPCSMQSLQSTCPPTYVPAVTYAAPAPIPPAMPSFVPGHSGLVHQQQRQLSPNPGEDIPWWSLQQGNPVAHSVHPHRFPIQRGLVLGHTDFAQYQTQIAALLHTKSPLATARRCRRCRCPNCQSSSSSDEPGKKKQHICHIPGCGKVYGKTSHLKAHLRWHSGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFVCPDCCKRFMRSDHLAKHVKTHQNKKSKSHDKTSDYVKREDLRPV
Protein: Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6) (Q64119)
Organism: Rattus norvegicus (Rat)
Function: Regulatory light chain of myosin. Does not bind calcium.
Interaction partners:
- Myosin-9
- Myosin-10
- Myosin regulatory light chain 12B
- Myosin regulatory light chain RLC-A
- Myosin-10
- Myosin regulatory light polypeptide 9
- Actin, cytoplasmic 1
- Myosin light chain kinase 3
- Actin, aortic smooth muscle
- Actin, gamma-enteric smooth muscle
Sequence:
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEELLRMVLNG
Protein: Vacuolar protein sorting-associated protein 2 homolog 2 (AtVPS2-2) (Charged multivesicular body protein 2 homolog 2) (ESCRT-III complex subunit VPS2 homolog 2) (Q0WTY4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity).
Subcellular location: Endosome {ECO:0000250}.
Interaction partners:
- ESCRT-related protein CHMP1A
- Vacuolar protein sorting-associated protein 32 homolog 2
- Vacuolar protein sorting-associated protein 32 homolog 1
- ESCRT-related protein CHMP1B
- Vacuolar protein sorting-associated protein 60.1
- Vacuolar protein sorting-associated protein 24 homolog 1
- Vacuolar protein sorting-associated protein 60.2
- Putative vacuolar protein sorting-associated protein 24 homolog 2
- Vacuolar protein-sorting-associated protein 37 homolog 2
- Vacuolar protein sorting-associated protein 36
Sequence:
MNIFKKKTTPKDALRTSKREMAVATRGIEREITSLQLEEKRLVAEIKKTAKTGNEAATKILARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAPKGRIATKTAAPPASTAATNKNSESSEVDELEKRLASLRRI
Protein: ENAH, actin regulator (A0A8I5Y4S4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection, lamellipodium {ECO:0000256|ARBA:ARBA00004510}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQEAGPTLPRQNSQLPAQVQNGPSQEEMEIQRRQLQEQQRQKELERERMERERLERERLERERLERERLEQEQLERQRQEREHVERLERERLERLERERQDRERERERLEQLEREQVEWERERRMSNAAPSSDSSLYSAPLPEYSSCQPPSAPPPSYAKVISAPVSDAAPDYAVVTALPPTSTPPTPPLRHSATRFATSLGSAFHPVLPHYATVPRPLNRNSRPSSPVNTPSSQPPAAKSCAWPTSNFSPLPPSPPIMISSPPGKATGPRPVLPVCVSSPVPQMPPSPTAPNGSLDSVTYPVSPPPTSGPAAPPPPPPPPPPPPPPPPPPPLPPLASLSHCGSQASPPPGTPLASTPSSKPSVLPSPSAAAPASVETPLNPELGDSSASEPGLQAASQPAETPAPQGHVLGPPAPPPPPPLPSGPAYASALPPPPGPPPPPPLPSAGPPPPPPPPPPLPNQVPPPPPPPPAPPLPASGIFSGSMSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPSGGNTVSVNLASSKTDSGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDRSEDAEPVTSKAASTSTPEPTRKPWERTNTMNGSKSPVISRRDSPRKNQIVFDNRSYDSLHRPKSTPSSQPSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA
Protein: Nanos homolog 1 (Xcat-2 protein) (Q07937)
Organism: Xenopus laevis (African clawed frog)
Function: Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES-driven, polyadenylated RNAs or nonpolyadenylated RNAs. Essential for the development of primordial germ cells (PGCs) by ensuring their proper migration and survival.
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:21195170}. Note=During early cleavage and blastula stages found close to the cell periphery in a germ plasm-like pattern. From gastrula stage on, detected predominantly in a perinuclear region.
Interaction partners:
Sequence:
MDGGLCFDSWSDYLGLSSLISRGLQPQREGERPRWDVLSPASAEPLPSNESVGHKGCGFCRSNREALSLYTSHRLRALDGRVLCPVLRGYTCPLCGANGDWAHTMRYCPLRRLLRDPQSNSNNPKLRH
Protein: IQ-domain 29 (F4IRA9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein IQ-DOMAIN 9
- Protein IQ-DOMAIN 15
- Protein IQ-DOMAIN 4
- Protein IQ-DOMAIN 12
- Protein IQ-DOMAIN 16
- Protein IQ-DOMAIN 33
- Protein IQ-DOMAIN 22
- At1g23060/T26J12_16
- Protein IQ-DOMAIN 10
Sequence:
MGKTPSPGKWIKSLLGKKSSKSSLEKGGEKLRSAKKEELVVKVKDNNVSKLPTEPPVVSSQEVAATQTVVVPDVVIAEKQLSGDIEGDESSNVNLESGNDSEEVKLEEAATKVQAALRAQQAREESQNLKGITRVQAVIRGHLVRRQAVATYSCIWGIVKVQALVRGKKARSSETVAQLQKTNTETETSETLQGSTYSWMENPTKLSMIDKLLVSSPTTLPLKIQYSPEDPNSAKVWLGRWTQLQVWAPGPLVVKNLVPKSQTKKRSFQAVEAEKGKLKRGVRKPTGVSTTANSSTSRSTADNEKPKRTVRKASTLGKELSKIENDKSKQSSRKSTSAIKEGSSVEVKDEKPRISHKKASLSNGIGKATRKSAEKKKEIADAVQKELPIEEVSVSLVDAPEDEKMNLIPVTISKESDLDKDEKSLVLDKPEQDELRTAERDDKAEEELKTAERDDSAEEKIQEPDAQISSENGNVASENTKPSDRRASLPAKIENHHQDDGLTQSGRKIPSYMAPTASAKARIRGQGSPRIAQEKPEKNGTTRRHSLPPAANGKLSTMSPRAHRLLIASAKGSMNSDRSFSSSKDIGGKRFKPITIHKPFCQFLLHYLHPFNKFSSCLYQTSRRKLSGNGESTKAE
Protein: Zinc finger protein 271 (Zinc finger protein 35) (Zfp-35) (P15620)
Organism: Mus musculus (Mouse)
Function: May act to control gene activity during the pachytene stage of meiotic prophase. May function as a transcription activator.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MEIQFSYESQDHHFLSDGETKIKIGEPATEEEMTGKIGTVTEESGSLEEDVPHDSRGKEFREFGEELNDQMLFRRRQYNCDECDQSFAWSTGLIRHQRTHWKPYECEECGKAFRMSSALVLHQRIHTGEKPYPCSWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLMIHQRIHTGEKPYQCSHCSKSFSQHSGMVKHLRIHTGEKPYMCNHCYKHFSQSSDLIKHQRIHTGEKPYKCDVCGKAFSQSSDRILHQRIHTGEKPYPCAQCNKSFSQNSDLIKHRRIHTGEKPYKCSECGKAFNQSSVLILHQRIHTGEKPYPCNQCTKSFSRLSDLINHQRIHTGEKPYPCSQCSKMFSRRSDLVKHYRIHTGEKPYECDKCGKTFSQSSNLILHQRIHTGEKPYPCNSCSKSFSRGSDLIKHQRVHTGEKPYTCNLCSKSFSQSSDLTKHQRVHSGEKPYHCSSCNKAFRQSSDLILHHRVHTGERPYACTQCPRSFSQKSDLIKHQRIHTGEKPYKCMCGKAFSQCSAFTLHQRIHTGEKPYPCAQCGKSFSQRSDLVNHQRVHADQKLQM
Protein: 2,4,6-trihydroxybenzophenone synthase (EC 2.3.1.220) (2,3',4,6-tetrahydroxybenzophenone synthase) (EC 2.3.1.151) (Benzophenone synthase) (HaBPS) (Q8SAS8)
Organism: Hypericum androsaemum (Tutsan)
Function: Type III polyketide synthase involved in the biosynthesis of benzophenones and xanthones. The preferred substrate is benzoyl-CoA, but can also use 3-hydroxybenzoyl-CoA with a lower activity.
Interaction partners:
Sequence:
MAPAMEYSTQNGQGEGKKRASVLAIGTTNPEHFILQEDYPDFYFRNTNSEHMTELKEKFKRICVKSHIRKRHFYLTEEILKENQGIATYGAGSLDARQRILETEVPKLGQEAALKAIAEWGQPISKITHVVFATTSGFMMPGADYVITRLLGLNRTVRRVMLYNQGCFAGGTALRVAKDLAENNEGARVLVVCAENTAMTFHAPNESHLDVIVGQAMFSDGAAALIIGACPDVASGERAVFNILSASQTIVPGSDGAITAHFYEMGMSYFLKEDVIPLFRDNIAAVMEEAFSPLGVSDWNSLFYSIHPGGRGIIDGVAGNLGIKDENLVATRHVLGEYGNMGSACVMFILDELRKSSKVNGKPTTGDGKEFGCLIGLGPGLTVEAVVLQSVPILQ
Protein: Ferrochelatase-1, chloroplastic/mitochondrial (AtFC1) (EC 4.98.1.1) (Ferrochelatase-I) (AtFC-I) (Heme synthase 1) (Protoheme ferro-lyase 1) (P42043)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the last step of heme biosynthesis by inserting ferrous iron into protoporphyrin IX to produce protoheme. Produces heme for photosynthetic cytochromes, but does not seem to be involved in stress responses. May be involved in wound-induced supply of heme to defensive hemoproteins outside plastids. Regulates the expression of photosynthesis-associated nuclear genes in undevelopped chloroplasts through production of heme.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:9210462}; Peripheral membrane protein {ECO:0000305|PubMed:9210462}. Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:9210462}; Peripheral membrane protein {ECO:0000305|PubMed:9210462}. Mitochondrion {ECO:0000269|PubMed:9346891}. Note=(PubMed:9346891) describes experimental in vitro import of FC1 into mitochondria isolated from pea. However, (PubMed:11602264) shows experimental evidences that FC1 is not present in Arabidopsis mitochondria in vivo. {ECO:0000305|PubMed:11602264, ECO:0000305|PubMed:9346891}.
Interaction partners:
- Protoporphyrinogen oxidase 2, chloroplastic/mitochondrial
- Protoporphyrinogen oxidase 1, chloroplastic
- Magnesium-chelatase subunit ChlH, chloroplastic
- Heme oxygenase 1, chloroplastic
- Magnesium-chelatase subunit ChlD, chloroplastic
- Frataxin, mitochondrial
- Uroporphyrinogen decarboxylase 2, chloroplastic
- Magnesium-chelatase subunit ChlI-2, chloroplastic
- Protoheme IX farnesyltransferase, mitochondrial
- Magnesium-chelatase subunit ChlI-1, chloroplastic
Sequence:
MQATALSSGFNPLTKRKDHRFPRSCSQRNSLSLIQCDIKERSFGESMTITNRGLSFKTNVFEQARSVTGDCSYDETSAKARSHVVAEDKIGVLLLNLGGPETLNDVQPFLYNLFADPDIIRLPRPFQFLQGTIAKFISVVRAPKSKEGYAAIGGGSPLRKITDEQADAIKMSLQAKNIAANVYVGMRYWYPFTEEAVQQIKKDKITRLVVLPLYPQYSISTTGSSIRVLQDLFRKDPYLAGVPVAIIKSWYQRRGYVNSMADLIEKELQTFSDPKEVMIFFSAHGVPVSYVENAGDPYQKQMEECIDLIMEELKARGVLNDHKLAYQSRVGPVQWLKPYTDEVLVDLGKSGVKSLLAVPVSFVSEHIETLEEIDMEYRELALESGVENWGRVPALGLTPSFITDLADAVIESLPSAEAMSNPNAVVDSEDSESSDAFSYIVKMFFGSILAFVLLLSPKMFHAFRNL
Protein: Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein) (Q9CQU8)
Organism: Mus musculus (Mouse)
Function: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}.
Interaction partners:
- DnaJ homolog subfamily C member 24
- Elongator complex protein 4
- Mitochondrial inner membrane protease subunit 2
- KICSTOR complex protein kaptin
- GATOR1 complex protein NPRL2
Sequence:
MLRGVLGKAFRLAGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQNSDIVFAENLSRHFYGIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILSTSPSDVFKSRSYVPTGHVWLEGDNLQNSTDSRYYGPIPYGLIRGRIFFKIWPFSDFGFLRDSPNGQRFSDD
Protein: WAP four-disulfide core domain protein 1 (Prostate stromal protein ps20) (ps20 growth inhibitor) (O70280)
Organism: Rattus norvegicus (Rat)
Function: Has growth inhibitory activity.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MGSCDRKALWALSFLLLLLGSSSVQGTWEAMLPVRLAEKSQAEEVAATGSRQPHADRCPPPPRTLPPGACQATRCQSDSECPRHRRCCYNGCAYACLEAVPPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGAEPLLCPSGYECHILQPGDAAQGIPNHGRCVKQRRQAEGRVLRQKLHKEYPEGDSKYVAEPGKGQQRHFP
Protein: Coronin-2A (IR10) (WD repeat-containing protein 2) (Q92828)
Organism: Homo sapiens (Human)
Interaction partners:
- Nuclear receptor corepressor 1
- E3 ubiquitin-protein ligase COP1
Sequence:
MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTENELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL
Protein: L-ascorbate peroxidase (EC 1.11.1.11) (O04873)
Organism: Cucurbita hybrid cultivar
Interaction partners:
Sequence:
MAATALGSVAASSASSTTRFLSTATRATLPFSSRSSSLSSFKFLRSAPLISHLFLNQGRPSSCVSIRRFNAASHPKCLASDPEQLKSAREDIKELLKTTFCHPILVRLGWHDAGTYNKNIEEWPQRGGANGSLRFDVELGHGANAGLVNALKLIEPIKKKYSNVTYADLFQLASATAIEEAGGPKIPMKYGRVDVVGPEQCPEEGRLPDAGPPSPAAHLREVFYRMGLNDREIVALSGAHTLGRSRPERSGWGKPETKYTKDGPGAPGGQSWTVQWLKFNNSYFKDIKERRDEELLVLPTDAALFEDPSFKVYAEKYVEDQEAFFKDYAEAHAKLSNLGAKFDPPEGIVIDDASSKPAGEKFDAAKYSYGKRELSDSMKQKIRAEYESFGGSPDKPLPTNYFLNIILVIAVLAILTSLLGN