wanglab/gogpt-training-data huggingface dataset:
Protein: Leiomodin-3 (E9QA62)
Organism: Mus musculus (Mouse)
Function: Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q0VAK6}. Cytoplasm, myofibril, sarcomere, A band {ECO:0000269|PubMed:24960163}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:Q0VAK6}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q0VAK6}. Note=Highly expressed in nonstriated areas of developing myotubes, where it shows a granular cytoplasmic pattern. In sarcomeres, highly expressed in the M band region and, at lower levels, along actin thin filaments. Not detected in Z-disks. In sarcomeres, may be located near, but not at, actin thin filament pointed end. {ECO:0000250|UniProtKB:Q0VAK6}.
Interaction partners:
- Kelch-like protein 40
- Kelch-like protein 41
- Nebulin
- Kelch repeat and BTB domain-containing protein 13
- Nebulin-related-anchoring protein
- Myopalladin
Sequence:
MSGHSRNSEQEDTLSEELDEDELLANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTDKAPTGNFNHKSLVDYMYLQKASRRMLEDERVPVSFVQSEKNTQNQREVGDKGIKNMPQFLKEKLNSEILAKKRESNGSNNVQEAEDDDEDEEEEEEDDEDEEEEEEDEEDDEGEEDEDGEQANREKNDAKEQIHNNPGTYQQLATKTAHEQKDTSETKEKGEKKIAKLDPKKLALDTSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADESVAFALANMLRENRSVTTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANTTLLKMGYHFELPGPRMVVTNLLTRNQDKRRQKRQEEQQQQQLKEQRKLIAMLENGLGLPPGMWERLGGPMPDPRMQEFFQPASGRPLDAQEVPFGSRKEMIKNPPQPPQCKTDPDSFRVVKLKRIQRKSRMPEAREAQEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNVAYLKPVQLPKELE
Protein: Insulin-like growth factor 2 (Insulin-like growth factor II) (Q862G1)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU000406}.
Interaction partners:
Sequence:
TLCGGELVDTLQFVCGDRGFYFSRPSSRINRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSASTTVLPDDVTAYPVGKFFQYDIWKQSTQRLRRGLPAFLRARRGRTLAKELEALREAKSXPSADRPATQDPATHGG
Protein: Protein LTV1 homolog (Low temperature viability protein 1) (Ribosome biogenesis factor LTV1) (Q7KN79)
Organism: Drosophila melanogaster (Fruit fly)
Function: Necessary for the biogenesis of 40S ribosome subunits by regulating pre-rRNA processing. Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit. Necessary for endoreplication driven by Myc.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25858587}.
Interaction partners:
- RNA-binding protein NOB1
- Pre-rRNA-processing protein TSR1 homolog
- Bystin
- Serine/threonine-protein kinase RIO1
- Serine/threonine-protein kinase RIO2
- Small ribosomal subunit protein uS3
- KRR1 small subunit processome component homolog
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein eS12
- 40S ribosomal protein S15
Sequence:
MVKGKKPYIDRKKAVTFHLVHRSQHDPLVTDENAPQRVLLEAAARQQKPKDPEPPTDPAQRQEELKKFGIHFDDDYDYMQHLKKRENDVVWEFMENPNQARKQKVQDSEKPGPAPKLMLPSSVFASEFEESEGMLNKAAPQTLRLDWDPDVVAALDSDCENEELEDDFVIQAMAEGDSDDEEWDDEDGEEQSDMDFDSDDLNEDENEDELMDRLAPLMRERRFDDEEVKSRFTEYSMSSSVIRRNEQLSLLDDRFEKFYATYDDPELGDLALEDIEGNWHQKHPVVMQCFQEFKKKDKGIEYNKEWDRERIEKYRNVVEGEEDPTEELVEYEVDDPKQKKWDCESILSTYSNIYNHPKVIDEPRRSRRSSASTNPAPIQIDPKTGLPTNVLRGGVDGQLTAKALANLADESPAATGPKSLCAKSVLSTLSVLSIRPKDETHEEKKERKRLLKDYRNERRIEKKANTEAFKEEKKRQTHVKINQRTNQQGASIV
Protein: Syndecan-3 (SYND3) (N-syndecan) (Neuroglycan) (P33671)
Organism: Rattus norvegicus (Rat)
Function: Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism (By similarity).
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Pleiotrophin
- Proto-oncogene tyrosine-protein kinase Src
- Glial cell line-derived neurotrophic factor
- Src substrate cortactin
- Syndecan-2
- Neurturin
- Syndecan-4
- Hematopoietic lineage cell-specific protein
- Glypican-3
- Artemin
Sequence:
MKPGPPRRGTAQGQRVDTATHGPGARGLLLPPLLLLLLAGRAAGAQRWRNENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGLETAMRFIPDIALAAPTAPAMLPTTVIQPVDTPFEELLSEHPGPEPVTSPPLVTEVTEVVEEPSQRATTISTTTSTTAATTTGAPTMATAPATAATTAPSTPAAPPATATTADIRTTGIQGLLPLPLTTAATAKATTPAVPSPPTTVTTLDTEAPTPRLVNTATSRPRALPRPVTTQEPEVAERSTLPLGTTAPGPTEVAQTPTPESLLTTTQDEPEVPVSGGPSGDFELQEETTQPDTANEVVAVEGAAAKPSPPLGTLPKGARPGLGLHDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQEEFYA
Protein: Uncharacterized protein, isoform E (X2JEY3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MATTAAGIQQQQVIGLGAAYDRQQSTDSGWDNPFRPGGDLSREADEIVNMIRGGKPITPTEERTIGNGSAQHADDNCNGGTAIGESVIKSNGLCHLQLSQNLATAQNGTNSHASATADAGAGKAATATELSGGTGNNGVTSLGQVSKQVVPGPTSASHVVIDEKKNKKKGCCVLQ
Protein: Erythrocyte binding antigen-140 (Q76NM5)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Nucleoporin NUP221, putative
Sequence:
MKGYFNIYFLIPLIFLYNVIRINESIIGRTLYNRQDESSDISRVNSPELNNNHKTNIYDSDYEDVNNKLINSFVENKSVKKKRSLSFINNKTKSYDIIPPSYSYRNDKFNSLSENEDNSGNTNSNNFANTSEISIGKDNKQYTFIQKRTHLFACGIKRKSIKWICRENSEKITVCVPDRKIQLCIANFLNSRLETMEKFKEIFLISVNTEAKLLYNKNEGKDPSIFCNELRNSFSDFRNSFIGDDMDFGGNTDRVKGYINKKFSDYYKEKNVEKLNNIKKEWWEKNKANLWNHMIVNHKGNISKECAIIPAEEPQINLWIKEWNENFLMEKKRLFLNIKDKCVENKKYEACFGGCRLPCSSYTSFMKKSKTQMEVLTNLYKKKNSGVDKNNFLNDLFKKNNKNDLDDFFKNEKEYDDLCDCRYTATIIKSFLNGPAKNDVDIASQINVNDLRGFGCNYKSNNEKSWNCTGTFTNKFPGTCEPPRRQTLCLGRTYLLHRGHEEDYKEHLLGASIYEAQLLKYKYKEKDENALCSIIQNSYADLADIIKGSDIIKDYYGKKMEENLNKVNKDKKRNEESLKIFREKWWDENKENVWKVMSAVLKNKETCKDYDKFQKIPQFLRWFKEWGDDFCEKRKEKIYSFESFKVECKKKDCDENTCKNKCSEYKKWIDLKKSEYEKQVDKYTKDKNKKMYDNIDEVKNKEANVYLKEKSKECKDVNFDDKIFNESPNEYEDMCKKCDEIKYLNEIKYPKTKHDIYDIDTFSDTFGDGTPISINANINEQQSGKDTSNTGNSETSDSPVSHEPESDAAINVEKLSGDESSSETRGILDINDPSVTNNVNEVHDASNTQGSVSNTSDITNGHSESSLNRTTNAQDIKIGRSGNEQSDNQENSSHSSDNSGSLTIGQVPSEDNTQNTYDSQNPHRDTPNALASLPSDDKINEIEGFDSSRDSENGRGDTTSNTHDVRRTNIVSERRVNSHDFIRNGMANNNAHHQYITQIENNGIIRGQEESAGNSVNYKDNPKRSNFSSENDHKKNIQEYNSRDTKRVREEIIKLSKQNKCNNEYSMEYCTYSDERNSSPGPCSREERKKLCCQISDYCLKYFNFYSIEYYNCIKSEIKSPEYKCFKSEGQSSIPYFAAGGILVVIVLLLSSASRMGKSNEEYDIGESNIEATFEENNYLNKLSRIFNQEVQETNISDYSEYNYNEKNMY
Protein: H/ACA ribonucleoprotein complex subunit cbf5 (EC 5.4.99.-) (Centromere-binding factor 5 homolog) (O14007)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. Catalyzes pseudouridylation at position 93 in U2 snRNA. Also catalyzes pseudouridylation of mRNAs; H/ACA-type snoRNAs probably guide pseudouridylation of mRNAs.
Subcellular location: Nucleus, nucleolus {ECO:0000250|UniProtKB:P33322}.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit gar1
- Protein shq1
- H/ACA ribonucleoprotein complex subunit nop10
- Nucleolar protein 58
- H/ACA ribonucleoprotein complex subunit nhp2
- Nucleolar protein 56
- rRNA 2'-O-methyltransferase fibrillarin
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- 13 kDa ribonucleoprotein-associated protein
- ATP-dependent RNA helicase has1
Sequence:
MTDTHPGVDFMIKPEATSASKIDTAEWPLLLKNFDKLLVRTGHYTPIPCGNNPLKRPIAEYVSSGVINLDKPANPSSHEVVAWVKKILRVEKTGHSGTLDPKVTGCLIICNDRATRLVKSQQSAGKEYVCVLRLHDSVEGERNVASAIETLTGALFQRPPLISAVKRQLRIRSIYESKLIEFDNERNLAVFWASCEAGTYMRTLCVHLGLLLGVGGHMQELRRVRSGCLSENDDIVTMHDVLDAQWIYDNTRDESYLRRVIRPLESLLVGYKRIVVKDSAVNAICYGAKLMIPGLLRYEAGIEVNEEIVLITTKGEAIAVGIAQMSTVELSTCDHGVVAKVKRCIMERDVYPRRWGLGPQSMKKKTLKKEGKLDKYGRPNENTPADWSKSYIDYSDPNAEVAKPAPVVAPAAPTVEAEVNGVEDSKKRKSVESSEKDEDEAAKKEEKRRKKEAKKEKKEKKEKKEKKEKKKKSE
Protein: Pericentrin-like protein, isoform L (M9PI63)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
Interaction partners:
Sequence:
MNLYTIYDWITSLLRPHGASVSYKAIEAATLEELPATSVATATSTAATSRATGGAAATCVDVEFIPTLNIIFEKPTSSSEQLQCAEKSEHVAGGVSDKEPADDCDSDNDSTRTYIISRSSWTGVTSSSSTPYAVTSTDTAELLRRQNNLSLTEEDQSVSSFSIEQPTSSITIEMADQRTTTTTTTTATTATTPSSANILATTATTTTTTSSSIEEEIEEAIEISEVEEQLNTPLESLSEAAAYARPKDEQSSAKSLSSNPAEDEDADEFRIDDAQLSGGQLAQHFLVDEDESEEGSDLPAASKVEVSLSSNDDDFDISLPLEQRKPVHSLHEDDESVDQSLSNQSTTDDVSELVEEPVHEMDDKTDGSAAISASAPQETQVDESQITDEQDHSMEEIVATNESIEVTYEAEETVNTSQKQDLITDLDEESEDQVHVDNRPTSTLQALKLPALQQPQIVERKAATALTTLRLQADVLEPLELTILEMDDDENEEDDDDEESSLQLMKLRLMAMNQQMIVDNAPKLSPTEAEQTQVTSSSNNLEIKQMERVPLTEFSKDVLEDITEESERLLSMSTTMEEEQDPPSLSLDESKTLLQPGAHKTGGSSSSLVSLNMLKQLEAKVQELHTQLETKDNCLASLNLQLETARRESSAGPASARDSSSLMTNSTEYRTLQEELGGPTLDIYVEMSRRDELIAKLTDSLQQSLNVRDKLQVDADRLGGEVQNLRRQLQETLDAVKRSSAVWPDQECNPGQRISEISMDLISESDDDLDRHFLTDNEERGSRSSKERQLTQLQTNEELGLQASNPEWTPTFSKQIEQFHTYLLPTEQRIFQMVQRKFDDYLNQQITLCRDLGAQELKIARDQWESEKLTSEQNQQAAHAKQMEDLRKYFEHKCADLEKQFSDDVFSHKSQHQTGDSSSECSEVDQLPEEGAAAVSSKEPSPRKRKRAELLLSPSHRQMTPCGLDSLGENTGKTEKDNTADIADLKIFYQTHIKELKRAHEDQVRKLSDRIKFYERQQGDDDYKPATESPERTCPDQESAGGVANTSLIIIDEDELNFNNESQVIQRIIEEYEKRLQEQLALARQDIATELEQQIKSLLSENTVDDQHWPKELILLREKFTAKSQLEITQLNIKHAEEMSRLKLEFEKQLNRKNKRHLTFDAARDLEQVICERDGLRELSKSFRSVLCRLAKCVAHCEEDLNATLSEEVQRLLFHSRSQDGGDDLEATISSSLNNTKHMLRVPDVHSLLEVVEDPSLVQFIDSKSNEEPSEDFDLNDCLERLKSEASYLLHLSEDLHKQRTHDESSEHLDEPEKQEHELCCEAEDGLKTTGAVNQQVLSKFLRTNSLNDQQMGVANQRKNSNPEAGKTHSSLPPDLQEHAGNASELSFQLVQLKNRLIKSEADRQNLQQQLSRTIDRNAELGQELQALRDQLSQLNSLNHTDYNEGYGLGTMKSLQEQGLDQSSASFLALQERARHLLSSSPVKEQPSRDHGNSTVILLQMIEDFCREGDKVVEFSKKDREDLQSQYAQLESQFREVNQQLCESNAKRDKFEVELKASIDKIFVLREIISELETQVQTKALNEEVLAEKAQQLEEYVSLQMRDNDILQQEVHSLKTDIGEGYQSRIRVLEEKLKQSGPTAEQGVVLSQVAEKLRDIETTLDQKTKALESLHNSNATSNSASLSVTEDVSIHGSKEPTAVGSPSHPSLTVEGVQRVTEKLDRHTRVEEAAIKRIRDLEMQVHQMRAGCVELQHERDTLQGRMEEQTQRISTLQNRLEEQRQRAEQLHRTGTSDLNTRVHELQGEVQNLYEQLAARDKQMANMRQQLQRSKEEITRLETEVEVRTQPDRSLVNKLQAEVQQKGAEIVKLKDKIRTEMINRLAIPDLMETMLADKNDEIDHLRDQLEAKEKELQASQQEASQISSPSGAAGKQEGSGGKLSARTLSDIGSITEFPEPDVERRAAMRSLTALQMSEGAGGFLHQTMETSKEAVANLTHKRTDDLSGFIVPYPVNTFEHPHYFQALGVTAQSTDGLTPGLVPRQINFSNLTEDSKLKTTSLLMHTPELPRPTTPPEIHQLRVKLSDLQTEKQRQQSELEKKLQDLQKELEQEKEKLSRQAQTLQSYEESEAKYRLRIENLESKVLETAAQAASDRENLRKELNCVSAAHEQCENAAAARKRELEKLNSEVKVKADQLHAALRRCADLELQVLTLERDLERLKNSDNSSKQYSVDEIAQQVEKELNYSAQLDSNILKAIESEEENNLDKKLQKGVQTEEETLPGTGNGTDDENFTGERELLNQLEALRAQLAVEREQCEAMSKELLGEKQHSQDIQEQDVIIIEAMRKRLETALDAEDELHKQLDQERERCERLQTQLTSLQRAESRRNSSLLLKSPGDSPRKSPRADFESELGDRLRSEIKLLVAQNERERERSADAQRSSERERQRYEKELQERVAYCERLKQEMEKLSRDKESAETELEHFNERLTLQASEIESLEARLVTLQEAETRRANTRTRQHQENVKLQAEIHELKSKLLAAEAARDCLDQKVTQLRFDVSRSGQREAKLAEALAQANDRLAHSTDDNVPAQFMQKMKEINALLAENTQENRQMAETVQFLVGERIALQKKCEELGGAGNTNVTELEERCRQLIGRYLRVESHRKALVYQKRYLKLTLEGYQASEQLALQNLRGGAEQPPQRNIKKKFKTVALAIIAIQRIKYIGRIWHTGKRIVSKSVFTITQQRSPGLNLNVAPPQSPLPGPNSNLPTNNNNLMGRLSYAPLSPPMVNFSTVQPIMLPSDFTLQAPTTSLQTTIANNNSENTLPSLARLDWPTMQKPKRAHARHH
Protein: Ferrochelatase (EC 4.98.1.1) (Q9DFU9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000607}.
Interaction partners:
Sequence:
MAVLGGACRLVQLVRCGSPVGLCLSSSLRRQSTATAAAFNTTATPETKESRKPKTGILMLNMGGPEKLEDVHDFLLRLFMDTDFMQLPVQNKLGPFIAKRRTPKIQEQYSKIGGGSPIKAWTTMQGEGMVKLLDEMCPDTAPHKFYIGFRYVHPLTEEAIELMEKDGVERAVAFTQYPQYSCSTTGSSLNAIYRYYSNRADRPKMRWSVIDRWPTHPLLIECFAEHVRNELDKFPVEKRDDVVILFSAHSLPLSVVNRGDPYPQEVGATVQRVMDRLGHCNPYRLVWQSKVGPMAWLGPQTDEVIKGLCQRGKRNLLLVPIAFTSDHIETLHELDIEYSQVLGEEVGVENIRRAESLNGNPLFFRALADLVQSHLQSNESCSRQLTLRCPLCVNPTCAQTKAFFSSQKL
Protein: B4, isoform A (B4, isoform B) (B4, isoform C) (LD35137p) (LD48089p) (Q9VJX3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- B6
Sequence:
MNETLKLSGLGMQRTNIELERQRHLANWLMNSRPHMPGGPAAATTTSAAAATTPTASATKGATTTTATTTNPGSTVGGAGAGPVGGNGVATAAAAGAPSNSVAAAAAAACNGGAAVGAHHGHHSAAGARKPKLRRFNSHDTSSNMFSVADFENARLARRNEIELNQRRARRVRGSANNSTYGLGSGSGLLGGAHSGYCDALNGSGDYSTGDSKASKGSSEGALTAIEFLERNSLPRVVRILHASKSSNETLQSSSSHGSSTAASSSSSTGANPFGSGGSGGGNISSGNIDTGTHSSSSGGSATGNGTGSGPGLSSGSGSGSGSGHQNNNGRHSSNGGTPPGHDELFLLYRLVRQRNIYHGHNAKTQASQRKKTLLIPQEFPGYFSMLSEKGLPTATQYGSLIQLVRERVYKFVSVDNMPAFTESSPNSTSSPTHEGCLPINKGRPQYVKTTARGGQVFRLLAVFEDGKQDQVNMSQHGNGNATRSHGSGYMGREKEKNRYAQLLNENRQVLYVPLSTKGKFYEIEPGIPQLLQKLGDAQRKLNPECVHRLSALVTAAKQLPLTLRYISGPGGPDIPEQLCISQVSKEDVVVGCSIEDVDTQTPLQLRKFYPSRDIQLVKSYLGFDSEQRMLANTNVQNMLKFCQFNCDPFLKLVEIELIQRSERSGSKNREGLRILKPLHFPKILRREKSSMAAAHEKEDSIIFLSKSDLENLEAKEAAASAAAHSESSLNRISERMRVFQSTKKKWFGKHHPQQQQPQIEKHQSDLDLDEQAKRMSMERYTDMSKLLQERFGSNPEQPEQDAISLNSTAASDTETTMLTTMEPRSLDTMMQKSMSLQDIELLNGQCKQRPDLLASHNHNDAISEAGTELEDVENQTPPPQSFITEKLYNEFHVKTRQYSKSSSSLHQLPLFSLPQKLQLHEAEKEKRHLMLLKAQQQALTKEPVTGRRAAGGVSLLGGGLNQLAISPASLVEDDLPYSSVRDSLVISGGDCLRSESASRPVPAVDYTKENIYAEICPSHTVDTFSGATQFTHVPDDDGDYASLKYSVNGPQSVSRIEVNGATAAVKSSAISYHTVYLGEEPLGERHAAHITTVELAGEDNIYNTLK
Protein: RNA helicase (EC 3.6.4.13) (K7EPJ3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XDEEEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEI
Protein: Uncharacterized protein (Q580V6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MFVRKFQGEILKKEGHEPPKGDKAQGSHSMSLTTSFVDPENAKRERPVVDVSAPYNPLDETHQIRKLGVQKLAIGFLSLNGFTGAHEEVPYTDSMSTYECVRYGMIGLNVWFANFFLVRAGNSGSPVGHPRTRFAWNIAFLMGIIRVNLAGIVGIGGYFYSYEWLYTHGPAMFRIKDPSPNAYKRAWDEGQSCYLSRAAACIFPPLGYAIFMGRWKKTAFWFVFTLAMSMQYEYARHYILPGMRLFYSFQANRETQRQANWGSLAPVLEHRVDPDTNRNASVAASRYMRITQGPLQDTIWANATHENLPFHRYGMKLPNPYYNWQKAPQGYNSKPYRFKNDLWDLPNVLNTSKANFRI
Protein: Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50) (Q05048)
Organism: Homo sapiens (Human)
Function: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:10477523}.
Interaction partners:
- Cleavage stimulation factor subunit 2
- Cleavage stimulation factor subunit 3
- Cleavage and polyadenylation specificity factor subunit 2
- BRCA1-associated RING domain protein 1
- Cleavage stimulation factor subunit 2 tau variant
- Cleavage and polyadenylation specificity factor subunit 3
- Breast cancer type 1 susceptibility protein
- Cleavage and polyadenylation specificity factor subunit 4
- Cleavage and polyadenylation specificity factor subunit 1
- Pre-mRNA 3'-end-processing factor FIP1
Sequence:
MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD
Protein: Scaffold protein ILK (ILK-1) (ILK-2) (Inactive integrin-linked kinase) (p59ILK) (Q6PHD6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, myofibril, sarcomere {ECO:0000256|ARBA:ARBA00004204}.
Interaction partners:
- Gamma-parvin
- Actopaxin
- Parvin, alpha b
- Beta-parvin
- Paxillin
- Paxillin
- LIM domain-containing protein.
- Integrin beta
- LIM domain-containing protein.
- Ras suppressor protein 1
Sequence:
MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSGVVDMLIMRGARINVMNRGDDTPLHLAASHGHRDILAKLIQCKADTNAANEHGNTPLHYACFWAHDQVAEDLVSNGAQVSICNKYGETPMDKAKPPLAANLKDLAEKQGQSLSKVPYKDNFWKGTTRTRPRNGTLNKQAGIDYKQLNMLNKINENHSGELWKGRWQGTEIVVKMLHVREWTTRKSRDFNEEYPKLRIFSHPNVLPVLGACQSPPAPHPIIITHSMPYGSLYNLLHEGTNLVVDQNQAVKFALDIACGMAFLHTLEPMIPRHYLNSKSVMIDEDMTARISMADVKLSFQCPGRMYSPAWVAPEALQKKPEEINRRSADMWSYAVLLWELVSREVPFADLSNMEIGMKVALEGLRPTIPPGISPHICKLMKICMNEDPAKRPKFDMIVPILEKMQDK
Protein: calcium/calmodulin-dependent protein kinase (EC 2.7.11.17) (E9QDQ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MATTTCTRFTDEYQLYEELGKGAFSVVRRCVKLSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSVGSRQTTAPASVTAAAAAVAAAAGTTAGLVEQAKTLLNKKADVKPQTNSTKNSIVTSPKGNLPSPALESSDSSNATVEDEEMKARKQEIIKITEQLIEAINNGDFEAYAKICDPGLTCFEPEALGNLVEGMDFHRFYFENLLSKNSKPIHTTILNPHVHLIGEEAACIAYIRLTQYVDGQGRPRSSQSEETRVWHRRDSKWQNVHFHCSGAPAAPLQ
Protein: Purine-cytosine permease fcyB (PCP fcyB) (Cytosine/purine transport protein fcyB) (Fluorocytosine resistance protein fcyB) (C8V329)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: This permease has a broad specificity towards purines, and also transports cytosine, but neither uracil nor thymine. Contributes very little in purine uptake. Its major role may be the uptake of cytosine.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18384518}; Multi-pass membrane protein {ECO:0000269|PubMed:18384518}.
Interaction partners:
Sequence:
MAGAFDFDLEKNPPVVQSTADNSSDGAVPGETFTYGDSTYAKIQRLAAELNIEQRGIERVPAAEQTDTSVFNIGSMWLAANMVVSSFAIGVLGKSVYSLGFVDAILTVLFFNLLGIMTVCFFSCFGPFGLRQMVFSRLWFGWYVTKGFAVLNILACLGWSAANAIVGAQMLHAVNSDVPGFAAILIISICTLLVTFAGYKVVHLYEYWSWIPTFIVFMIILGTFAHSGDFQNIPMGVGTSEMGSVLSFGSAVYGFATGWTSYAADYTVYQPANRSKRKIFLSTWLGLIVPLLFVEMLGVAVMTATDIKGSKYDVGYATSGNGGLIAAVLQPLGGFGDFCLVILALSIVANNCPNFYSVALTVQVLSRYAQRVPRFIWTLFGTGVSIAIAIPGYSHFETVLENFMNFIAYWLAIYSAIAIMDHFVFKRGFSGYVVENFDKREKLPVGIAATIAFGFGVAGMITGMSQPWYVGPIARHAAGGDVGFELGFAFAAFSYLCLRPFEIKFFGR
Protein: Dynein axonemal intermediate chain 3 (WD repeat domain 63) (A0A0G2KIZ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May be involved in the regulation of cilia function.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8IWG1}.
Interaction partners:
- Dynein axonemal intermediate chain 4
- WD repeat-containing protein 37
- WD repeat domain 47a.
- Dynein, axonemal, heavy chain 1.
- Dynein axonemal heavy chain 10
- Dynein, axonemal, heavy chain 5.
Sequence:
MKDTSSKRPKSKEANKKKTKDKSNADNLPKPEEAAASEPGHPEYIFPLVLTSVSQELFGCRADEDVTAENPHKLLKKQDIIQDLRHRAAVCDFSPVKQAVLDYPEDELLLVFDRDFIYGQSFYLVLTVQAKESILKPPAEGADEQMEDEEQQEEEEEMMTKTPEPQPWVSLGSERLVYTPSAVLSSVICVRQLRYSVCPLGRRSGTRVRFSDRNALDWKEELVECSSYEDKSFSITRMERDSSTQTCRDNTHTCTQTLWKKPKNMWSQYEPREFSSEEKQHQLQSENLKNFITSVARRFEIYLQQNLIADVFCDDWTALCEDDASLMGKTETQLKEYQSFMDLHFSKEKTISHVQWHPSISGVIVVSMMERLSLEERIDSSTKLLLNPSHILFWSFSDPINPQLQLECPDDVLCFQFSPSDHNIIAGGCMNGQVVLWDISAHVDRLQDTRSGGKNILNKLGKSDATPVVRYCAVSGIENGHKAPITDIQWLPETFEVNKLGTPVENQSRTSVQLVTCAPDCCVLFWDLRAPRVMVHSLTDIKQKQEEKPLENPHGVPNTFTHLNLTWKPFIRVSLPKISSSGEYSPLRFSMRENTVDYNTGDKSVSGADSRVFAQLRMQSAKQQKPLQNISTKLYIATEDGELVYTDWKVEKDNDSGRMLSAKPLDVFLLQDTLLHTVSRSPFFRDIILTVGRFSFSIWREGLTCGPLLMSVYSKSMFSAGHWSRSRPAVLFMGREDGDVEVWDLLQNSRQPSHTQNISTAAISCIRTQTSSGNTHPYTETLHTHTHTQPPSAAYAHRPAPVTHTHTHKHCTHTHTHTHTHTHTHSRHQLHTHTDQLRVLEERVREAKQNLLAVSDRLGTLHILQIPGSLRRSSSSERQNVEKYFEKEEERLQYFEKRQSDHQKKKKETEAEQQKKKTELVTPPKQEEEVNAETLKEYQQFLTLEKLILKDMNIQNETQQTCNTINTP
Protein: Kinesin-related protein SMY1 (Suppressor protein SMY1) (P32364)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Possible microtubule-based motor that can interact or substitute with myosin 2 (MYO2).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}.
Interaction partners:
- Myosin-2
- Tubulin beta chain
- BNI1-related protein 1
- Ras-related protein SEC4
- Tubulin alpha-1 chain
- Tubulin alpha-3 chain
- Restriction of telomere capping protein 4
- Protein ECM13
- Myosin-4
- Tropomyosin-1
Sequence:
MHWNIISKEQSSSSVSLPTLDSSEPCHIEVILRAIPEKGLQNNESTFKIDPYENTVLFRTNNPLHETTKETHSTFQFDKVFDANATQEDVQKFLVHPIINDVLNGYNGTVITYGPSFSGKSYSLIGSKESEGILPNICKTLFDTLEKNEETKGDSFSVSVLAFEIYMEKTYDLLVPLPERKPLKLHRSSSKMDLEIKDICPAHVGSYEDLRSYIQAVQNVGNRMACGDKTERSRSHLVFQLHVEQRNRKDDILKNSSLYLVDLHGAEKFDKRTESTLSQDALKKLNQSIEALKNTVRSLSMKERDSAYSAKGSHSSAYRESQLTEVLKDSLGGNRKTKVILTCFLSNVPTTLSTLEFGDSIRQINNKVTDNTTGLNLKKKMDLFIQDMKIKDDNYVAQINILKAEIDSLKSLHNKSLPEDDEKKMLENTKKENIKLKLQLDSITQLLSSSTNEDPNNRIDEEVSEILTKRCEQIAQLELSFDRQMNSNSKLQQELEYKKSKEEALESMNVRLLEQIQLQEREIQELLTTNAILKGELETHTKLTETRSERIKSLESSVKELSLNKSAIPSPRRGSMSSSSGNTMLHIEEGSEISNSPWSANTSSKPLVWGARKVSSSSIATTGSQESFVARPFKKGLNLHSIKVTSSTPKSPSSGS
Protein: Acetyl-coa carboxylase (EC 6.3.4.14, EC 6.4.1.2) (B7G7S4)
Organism: Phaeodactylum tricornutum (strain CCAP 1055/1)
Interaction partners:
- Malonyl-CoA:ACP transacylase
- Acetyl-coa c-acetyltransferase
- Acetyl-coenzyme A synthetase
- Acetyl-coenzyme A synthetase
- Malonyl-coa decarboxylase
- ATP-citrate synthase
- Biotin carboxylase
- Malate synthase
- 2-isopropylmalate synthase
- (R)-citramalate synthase
Sequence:
MLSRGYATAALALLVAAAAHHASAFTSNSPAAFLSNGLAKVQRQNVVGVSRENDRGLDTALWSTLDEPITLGGVKALEDYVKERGGNLPIRKVLIANNGMAATKSILSMRQWAYMELGDERAIQFVAMATPEDLKANAEFIRLADSFVEVPGGSSANNYGNVDVICKLAQEQGVDAVWPGWGHASEKPALPDGLAKIGVKFIGPPAPVMSVLGDKIAANILAQTANVPSIPWSGSFGGTDDGPLQADLTDEGTIPDDIFEKATCRNVEEAIQAAEKIGYEEGLMIKASEGGGGKGIRFVDNEEDLRNAFIQVQSEVIGSPIFIMQLCKNARHLEVQIVGDEHGNAVALNGRDCSTQRRFQKIFEEGPPTIAKVDTFDEMQKAAQRLTQTIGYVGAGTVEYLYNAATDKYFFLELNPRLQVEHPVTEGITGVNMPATQLQVAMGIPLYNIPQIRHLYGKEDIYGTDKIDFMVEKYKPIDTHVIAARITAENPDEGFKPTSGSIERIKFQSTSNVWGYFSVGANGGIHEFADSQFGHLFAKGATREQARKSLILALKEIEVRGEIRTTVEYLAQLLETKEFIENTIDTSWLDGIIKSKSVQIEMPEDLTVISAAVFKAFKHVEEAVEDVKESFRKGQVSVGGVPAMNSFDIEIAYKDTKYTFHVERTAEDLYLLSCAGNTIEVRLTLTAESAILATFGGETHRIDGMDEPLGLRLVLDGNTILMPTIFDPSELRTDVTGKVVRFLQDNGGSVEAGQPFVEVEAMKMIMPLKATESGKITHNLSPGSVISAGDLLASLDLKDPSKVKKIVTFEGEFKIPSVALETAATDMISHILAGYQGDAEFAANAAFEDIEDVETAATLVTDTLNEFLRVEKIFNGRLLDDVVRDLTKANSENLDHVIAEIQAHLNVRLRSQLILAMLRQVETFSDRFGVAEISGDLLAALEELQTLKDKMYGEITLAADTIIRQSKIPSFESRVEELRAQLSDTETDLVKLSKSPTLSAGVDLLTYLFTDSDGLVRSAAVEVYVRRVYRAHRMLDLSVEDKSGRLTCSFTFQFSDVPENEAPTRQGLLSVVASMDSFKSDFANILEDMSEAIGEKPATSDGRPLTALHIAMADGEMGEFSVVEGVLASEKPKLIAMGVRTVNFVVPNKKKEPSYFTFPQADNYKEDRLRRNMRPTFHHLLELARLTSNFDAERIPAIGKNAQVYIGTEKSERPVRGGPPQVVFVRAISHSSGLVTDVGALRALQQGLDELERAQSNSKVNLQSSSRIFLHSLHELEGTTPQEVSARFKAVMSSLKSKLATRLLKLRVDEIEVKLRIASKSEDGSPIVQNVRLVGSSMEGEWLGATTYIEKPDPVTGVTTEFCVLDESGEANMCFLDPYGTSNIIQTKRAIARRVGSTYAYDFLGLLEVALIGEWEQHINSLELDTGVTIPTDLFESQELIEDEDGNLVLGSRVVGTNKIGMVTWVVKMKTPEYPEGREVVVIANDVTVQSGSFGVEEDELYYKASVYARERKLPRVYIACNAGARIGLVDELKEKINIKFNDPTNPNKGFEYLYLTDEDYKALPEGALIASKVNEGWALSDIIGTKHGIGVENLQGSGKIAGETSRSYDEIFTLSYVTGRSVGIGAYLVRLGQRVIQMKQGPIILTGFSALNKLLGRDVYTSNNQLGGPQVMQPNGVSHDIVDDDQEGVTSIMKWLSFVPKTVGALPACRESADPVDRPVAWRPTPTPYDPRLMLSGTADVPGFFDKGSWKEYLSGWGKSVVIGRGRLGGIPMGAIAVETRLVDKVIPADPADPNSREAILPQAGQVLFPDSSYKTAQALRDFNKEGLPVMIFANWRGFSGGSRDMAGEVLKFGAMIVDALREYENPVYIYLPPHGELRGGSWVVVDPTINQEKMEMYADPDSRGGILEPAGITEIKFRTPDQLKVMHRQDPQLKLLDAELEMCEMEDDKAAIKEQIIAREEQLKPVYLQAATEFADLHDKTGRMKAKGVIREAVPWEQSREFFFWRAKRRMLEDAAAGQMRQGDASLTKDSATDLLKDVFSGDWNDDKAVADFFESNASDVADKVKAVKAAGVQAKIDALKKELDGLEFM
Protein: Serine rich endogenous peptide 1 (AtSCOOP1) (Phytocytokine SCOOP1) (Precursor of serine rich endogenous peptide phytocytokine 1) (Q3E8H4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:B3H7I1}. Secreted, extracellular space, apoplast {ECO:0000250|UniProtKB:B3H7I1}. Note=The precursor of SCOOP1, PROSCOOP1, accumulates at the plasma membrane and is proteolytically cleaved to release the SCOOP1 in the apoplasm. {ECO:0000250|UniProtKB:B3H7I1}.
Interaction partners:
Sequence:
MGMSGSSGLVHVLMLLLLLSILFHHTESTLPSDSEQLSITGRRMMANYKPNTAVETPPSRSRRGGGGQNTGAD