wanglab/gogpt-training-data huggingface dataset:
Protein: Trio, isoform A (Trio, isoform C) (Q7KVD1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Ras-related protein Rac1
- Ras-related protein Rac2
- Tyrosine-protein kinase Abl
- AT17867p
- Netrin receptor unc-5
- Guanine nucleotide exchange factor MSS4 homolog
- Uncoordinated 115a, isoform B
- Uncoordinated 115b, isoform C
- Guanine nucleotide-binding protein subunit alpha
- Uncharacterized protein, isoform B
Sequence:
MDGQRARDLLTLLQERVVFLTGGRDRRGGPLLCFPATPRRDRLKPEDLRRLLSYLISIPSDAAKNLGFTVIIDMRGNGNCSTNVKTILKVLQEHFSANIHNVVIIKPDNFWQKQRASISSHKYKFETTTVSIESLNKIVESHQLTGDFEGQQLYDHQQWTDARLAIEDFFWQAGDMADRIDDLQEDLNRNDFAEDVPLARHAIDHHNEMRKKITKLPIEDLDMQGKKLLAKINAMAPPGGQAPTNSGGPDMDSGPSSAGQQSQPSQQSRSVGGNPDMSAAVNKALRQIELIHTGQEKLLMLWQHKKVKLDQCFQWRLFEQDCEKMFDWILHNRDVFQMSYVEIGHNYSVAKSLQDEHQKFAVASMNVSVNIDRILAVAARLIESQHYAAQHIKTLAQRLDRTWKDFAAGLDERTAVLQLSVLFHHKAEQYCNSVASWAAACQASQPLPSDIQSLETAIRTHQSLYEAMCQAYTEVHSTSKKLLYQLDHLVQVCNQPPPPGVPDHRKNSNNGSFNKYERQNPAADYSEGASHVLAVIHQILSHHRTLEAKWHQERLRLHQTLALRLFQEDVKQVLDWLKNHGEVFLRKNTGIGRNFHKARVYQTSHDNFENVAQNTYSNAQKLLAAADELARSGEADPNEIYSVARELELQVGSFAERVEQRRRRLDMAVIFYTHEKDVTAWIDKLRTDVSTDETRLSQENLEGIERILQQYQRDQQESSVNVCLTTISQGEALLQEMRSLEYADNTGSIAALEATLEKLNKQKVELEELWSARKFRADLILRLRYFERDARLLSVQMEMWSEELQHADLSRDYQKAEQLIRMHNESVTEIQNATYEVVQQGQDLLQLFENAGFISMADATHTAQARIEYLLDFLREREIDLEEMSEAKRAKLEQAVQLCQFQNDANQVISWIRNGEAMLVASFVTPNSLQEAEQLRKGHEQFQIAIEKTHTSAVQVKYRADALINANHYDPLSIDEISDDVTKKWQQLVTYAEERHKLVTASINFYKTAEQVCSVLDSLEREYKREDDWCDGGGGSDKAQAIVQLISKHQEQKEAFLKACTLARRTAETFLKYANRSQQCYQYKGNCEGHVKSKLDKLLTQENQVLDYWTLRKKSLDQCQQFVLFERSAKQAIEWIHNTGEAYLSSRSNLVGISKEETEGLLKEHNEFRSTAKETRERVKLLIQLADSLVEKGHAHASDIKQWVASVDQRYKDFSNRMDSYCEQLEKSLGMSQQQLLLGSDGNSSISSSSGDRHSDPTLEAKLNSSNKENKEINEEKRKSARRKEFIMAELMQTERAYVNDLATCIKCFLEEFRAGKSVPSALIGQEDVIFGNIKEIHHFHQKIFLRELEKYETMPEDVGHCFVTWASKFDMYVHYCKNKPTSNNLLVQHGGSFFEELQRRLEVDHPLPAYLIKPVQRITKYQLLLKDLLSCCEESHGEIKEGLEVMLNVPKKANDAMHLSLLENCDVSVDKLGEVVLQDAFQAWDTKQIIRKGRERRVFLFELYLLFAKEVKESNVVKYQFKSKLMTTDMGITEHIEGDETKFAVWTGRSPMLSDCRIVLKATSLETKQIWVKKLREVMQETCFSGTSLTLPKSPAKHSGSSQRSSRDLDEQLTENDHDRCSLASFGSGNTTDSDNKLGNQEATWVVADYIATSGSNELSVSKGQQVEIVEPPTAGEPDFCLVRLNPQHDDAAVQEGLVPVSVLKPPPGSHKHGSGTAANAASSAGSQKSDMQDQSNRSKADALSSSTKRRGFSGRNWLPLMNRKGTDKPPSSKPLVKKPSEKNLRTPQKHAEELAEQQNQQPGASPATVLPSSQFPSSTQHPGGAGAGDYEPDEEVGLELPPPMKPIQEPHLIANGPPAFAKDAKESSGNMASPGKMDGNPLSEIEEIVKTTTEQHESNSRVDGGGGVENASTNGHGRSHDNNDESHTAVSDKAAALKKRQCVFAELMSTEEAYVQDLHEIVNGYMTEINNTNSDIPMPEDLKGGKMKLVFNNIKDIYEWHRDFFLRALRNCQKSPADLGPLIKRSATKFALYYTYCSNKPLSEYIVSAHYQYFDSIRQKLGHRLDLSNLIIKPVQRITKYELLIKEIIKATEGAGLYKEVPMLQEAYQQMKVVVKTVNDMMVVLRSLQDFDGEITAQGSLLMQGPMNCVVDAAQKHRELQVFLFQQIIIFADIEKTKNQYASPIFKYRSHIQLNHMQMKELGDCRFQIRSTDPKIPEMTIICQAASQENYAGWRDMLNKILQQQNDLIFMLSNPLSTKNK
Protein: Lipid scramblase CLPTM1L (Cisplatin resistance-related protein 9) (CRR9p) (Cleft lip and palate transmembrane protein 1-like protein) (CLPTM1-like protein) (Q96KA5)
Organism: Homo sapiens (Human)
Function: Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a lipid glycoconjugate involved in post-translational modification of proteins. Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:35344438}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Telomerase reverse transcriptase
- Ribonuclease H2 subunit A
- Nuclear receptor subfamily 5 group A member 2
- Doublesex- and mab-3-related transcription factor 1
- Activating transcription factor 7-interacting protein 1
Sequence:
MWSGRSSFTSLVVGVFVVYVVHTCWVMYGIVYTRPCSGDANCIQPYLARRPKLQLSVYTTTRSHLGAENNIDLVLNVEDFDVESKFERTVNVSVPKKTRNNGTLYAYIFLHHAGVLPWHDGKQVHLVSPLTTYMVPKPEEINLLTGESDTQQIEAEKKPTSALDEPVSHWRPRLALNVMADNFVFDGSSLPADVHRYMKMIQLGKTVHYLPILFIDQLSNRVKDLMVINRSTTELPLTVSYDKVSLGRLRFWIHMQDAVYSLQQFGFSEKDADEVKGIFVDTNLYFLALTFFVAAFHLLFDFLAFKNDISFWKKKKSMIGMSTKAVLWRCFSTVVIFLFLLDEQTSLLVLVPAGVGAAIELWKVKKALKMTIFWRGLMPEFQFGTYSESERKTEEYDTQAMKYLSYLLYPLCVGGAVYSLLNIKYKSWYSWLINSFVNGVYAFGFLFMLPQLFVNYKLKSVAHLPWKAFTYKAFNTFIDDVFAFIITMPTSHRLACFRDDVVFLVYLYQRWLYPVDKRRVNEFGESYEEKATRAPHTD
Protein: Flagellar secretion chaperone FliS (P26609)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Subcellular location: Cytoplasm, cytosol {ECO:0000305}.
Interaction partners:
- Flagellar biosynthesis protein FlhA
- Flagellar hook-associated protein 1
- Flagellar protein FliT
- Flagellar hook-associated protein 3
- Flagellin
- Flagellar hook-associated protein 2
- Negative regulator of flagellin synthesis
- Flagellar hook-basal body complex protein FliE
- Flagellar M-ring protein
- Flagella synthesis protein FlgN
Sequence:
MYTASGIKAYAQVSVESAVMSASPHQLIEMLFDGANSALVRARLFLEQGDVVAKGEALSKAINIIDNGLKAGLDQEKGGEIATNLSELYDYMIRRLLQANLRNDAQAIEEVEGLLSNIAEAWKQISPKASFQESR
Protein: Hairy-related 11 (Her11) (Q6W4T8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Hairy and enhancer of split-related-7.
Sequence:
MKSTPTFNMTKTEGIKRRLKPVIEKKRRDRINHNLDALRDLLFKNTADTRLQNPKLEKAEILDLAVQYIKKTIRKTETARNSNQMDCKSTQNQFVISPAGPLYTSDYCRRFKTSEQNEVLLNLGVSQNLSGSSKTGNKLVSQKGFLLSPPGQNYHQELLLHPESSLYGSSLLRQSTSPSISSSSQYSSPPSSPTFTSTSCSPSSSPPCPSTSCAAFPDQLSPLITPLSLQRPVFVPQAILPHMTRDLTPPHSPVLALRQDPFPLPNQHAWRPWS
Protein: Gpr27 protein (Probable G-protein coupled receptor 27) (A9JRY2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MANTSEPGGSNPSLQNYAITASAVKLASLGLITCISLLGNSVLSVLVLKDSSLHKAPYYFLLDLCVADIIRSAVCFPFVMISINSGSVWSYSYISCKIIAFMAVLFCFHIAFLLFCVSVTRYMAIAHHRFYSKRMTLWTCVAVICMVWTLSVAMAFPPVFDVGTYKFIREEEQCIFEHRYVKANDTLGFMLMLAVIVATTHVVYVKMLCFVYDHRKMKPAQLVPAISQNWTFHGPGATGQAAANWIAGFGRGPTPPTLVGIRQAAHNANRRLLVLDEFKMEKRIGKMYYMITLAFLLFWAPYIVSCYIRVFVKGNALPQVYLSAAVWLTFAQAGANPIICFIFNKELRMRFRACLPCCLTTQTPMEPYCVI
Protein: Uncharacterized protein (Q57VF7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Transmembrane protein
- Mitochondrial fission process protein 1
- Thioredoxin domain-containing protein
- MICOS complex subunit MIC10
- Uncharacterized protein
- Uncharacterized protein
- Rhodanese domain-containing protein
- Uncharacterized protein
Sequence:
MAFGNASKGTDDYTPEEHLTAAVMEYKKLEAANQNSVEHMYNVLSSPFKIGSKPCEAIRGDALRCLSEIIGNFTAKSTSGTDGSTVMANSASIVSQELPPIHRCYESVLHYESCVLERTLSRHNSMVATFEARRLREADSAREAAAAGGDI
Protein: Possible alkyldihydroxyacetonephosphate synthase AgpS (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase) (O05784)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible flavoprotein
Sequence:
MRSWWGWGTVEDALSDQETQALQSRVAALVSGHDLSDHPPPDLTALGLAAPRVSPPASLAALCSSDLVDRAGHARGKAYRDIARNLQGQLDHLPDLIARPRSEQDVIDVLDWCAREGIAVIPYGGGSSVVGGVEPRFDEPVVTVDVTAMSAVLEIDRVSRAARIQAGAFGPSIEHQLRPHDLTLRHFPQSFGFSTLGGWLATRSGGHFATLYTHIDDLTESLRIVTPVGISESRRLPGSGAGPSPDRLFLGSEGTLGIITEAWMRLQHRPRWQVTVSVVFDDWAAAVAATRTIAQAGLYPANCRLLDPAEALLNAGTSVGGGLLVLAFESADHPIDPWLHRAVAITAEHGGTVTAQRSRGTTSDATEHNAAANWRSAFLRMPYQRDALVRRGVIAETFETACTWDGFDTLHAAVTDAARTAIWKVCGTGVVTCRFTHVYPDGPAPYYGIYAGGRWGSLDAQWDEIKAAVSEAISASGGTITHHHAVGRDHRAWYDRQRPDPFAAALRAAKSALDPAGILNPGVLLGR
Protein: Thioredoxin domain-containing protein 17 (Q9VMQ9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Caseinolytic protease chaperone subunit, isoform C
- ATP-dependent Clp protease proteolytic subunit
Sequence:
MVVTHNVKGYDEFTKKMEELENGDEPVHVLFSGGKDEKGESWCPYCVKAEPVIHDALKKAPGNSHFVHVDVGERAYWKDLNCPFRKDPNTHLIFLPTLLRWKRPQRLDGERCSNQDLVEMMFEDED
Protein: Serpin B12 (Q96P63)
Organism: Homo sapiens (Human)
Function: Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. May play a role in cell differentiation.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Caspase-14
Sequence:
MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYGEQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKAQILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP
Protein: Uncharacterized protein (Q38BH6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMRNSRFLLVVCNKAPARPGPMLYGWGRTEQKRRLEYESVESKYHKREFNKNWDLAGVEQRYTDFMVVRTYFSIGSRWGTWVYNMLQFYVLAFLPIFAFMHTLHKNVEWYDERIRHAAWW
Protein: Large ribosomal subunit protein bL27 (50S ribosomal protein L27) (P0A7L8)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Elongation factor G
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein bL20
- Small ribosomal subunit protein bS20
- Small ribosomal subunit protein bS16
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein bL21
- Large ribosomal subunit protein uL4
- Elongation factor Tu 1
Sequence:
MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
Protein: Histamine N-methyltransferase (HMT) (EC 2.1.1.8) (P50135)
Organism: Homo sapiens (Human)
Function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:26206890}.
Interaction partners:
- Diamine oxidase [copper-containing]
- Histidine decarboxylase
- Amine oxidase [flavin-containing] A
- Amine oxidase [flavin-containing] B
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- WD repeat-containing protein 5
- Host cell factor 1
- Histone-lysine N-methyltransferase SETD1A
- DNA
- Retinoblastoma-binding protein 5
Sequence:
MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
Protein: Protein phosphatase 1 regulatory subunit 12A (130 kDa myosin-binding subunit of smooth muscle myosin phosphatase) (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (PP1M subunit M110) (Protein phosphatase myosin-binding subunit) (Q90623)
Organism: Gallus gallus (Chicken)
Function: Regulates myosin phosphatase activity.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O14974}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:O14974}. Note=Also along actomyosin filaments. {ECO:0000250|UniProtKB:O14974}.
Interaction partners:
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
- Serine/threonine-protein phosphatase
- Rho-associated protein kinase
- Rho associated coiled-coil containing protein kinase 2
- Protein phosphatase 1 catalytic subunit alpha.
- Myosin light polypeptide 6
- Myosin regulatory light chain 2, smooth muscle major isoform
- Protein phosphatase 1 regulatory subunit.
- Uncharacterized protein
- Zinc finger CCHC domain-containing protein 17
Sequence:
MKMADAKQKRNEQLKRWIGSETDLEPPVVKRKKTKVKFDDGAVFLAACSSGDTEEVLRLLERGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEYLISQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQARYDVNIKDYDGWTPLHAAAHWGKEEACRILVENLCDMEAVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKREKKSPLIESTANLDNNQTQKTFKNKETLIMEQEKNASSIESLEHEKADEEEEGKKDESSCSSEEEEDDDSESEAETDKAKTLANANTTSTQSASMTAPSVAGGQGTPTSPLKKFPTSTTKVSPKEEERKDESPASWRLGLRKTGSYGALAEITASKEAQKEKDSAGVIRSASSPRLSSSLDNKEKEKDGKGTRLAYVAPTIPRRLASTSDIDEKENRDSSASSIRSGSSYARRKWEEDVKKNSLNEGPTSLNTSYQRSGSFGRRQDDLVSSNVPSTASTVTSSAGLQKTLPASANTTTKSTTGSTSAGVQSSTSNRLWAEDSTEKEKDSVPTAVTVPVAPSVVNAAATTTAMTTATSGTVSSTSEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETKDDDYRQRYSRTVEEPYHRYRPTSTSTSTSSTSSLSTSTSSLSSSSQLNRPNSLIGITSAYSRSGTKESEREGGKKEEEKEEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEHQSDSEEGTNKKETQSDSLSRYDTGSLSVSSGDRYDSAQGRSGSQSYLEDRKPYCSRLEKEDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKTTQRQERFADRSLLEMEKRVSGKSQYLLGGKKSSRKKDI
Protein: Bardet-Biedl syndrome 10 (A0A286Y9A6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MQMQQQLECVSLQVCVSVLGPLESVVRRCLGPEGGSVLFTRDTGETLISRHGQRVLSTLHLEHPMARMVLDCVCAHAKSTGDGTKSFILLLSALLRAIQDSAHMRRKASWSNPALQNLANRLMALSRNELDDIIIHQVTPYASSYCSHHSDKLEHSILDYLISGYISGRTGAGQAEILKHILCEFYYKSKRDQNTTETISFIHSHFNVLHTRVAGLPVGCSEVIEGLVVTRDWSVWTELRGPIKALVLYESFGSSLGDNITVCFQQDWLSRTESITKQKLAYLLELQVNVVLSSVKQPECVLQWARMNHVALLECVDSDQLDFLCNINFPETLSHPQHIVMLKYCKRLQLGGLRCAQLGIYSNAHTLVLCAPAPGLLDQTVCVSRGVFLMLQHITRTLESNQFKSSSVDQSQCTVSSQDLWRAVMQAGGVLPVGGVFEFLLHHFLLTRHTSDPESCRLLAEALLCVPRALYAHNHRRFLNIQTCFFNDLKKWDRTSVGDPVKFEFGFSEGLCLESVSGKQQLVVSVLECLHRLLCVGAVLYTRSLLRPQIYSEEDEEEEEEVHTNSI
Protein: Zinc finger protein 574 (Q6ZN55)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MTEESEETVLYIEHRYVCSECNQLYGSLEEVLMHQNSHVPQQHFELVGVADPGVTVATDTASGTGLYQTLVQESQYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPSPKAPPLSSSTIHYECVDCKALFASQELWLNHRQTHLRATPTKAPAPVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGATVPSAAATTTEVVTEVELLLYKCSECSQLFQLPADFLEHQATHFPAPVPESQEPALQQEVQASSPAEVPVSQPDPLPASDHSYELRNGEAIGRDRRGRRARRNNSGEAGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCPCGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEEPVIGFPEPAPAETGEPEAPEPPVSEETSAGPAAPGTYRCLLCSREFGKALQLTRHQRFVHRLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVVHAGRQPHRCPSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPPAPRAPRATRAPVASPAALGSTATASPAAPARRRGLECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEAEGVQISG
Protein: Y box binding protein 2 (A0A8I5ZJP8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSRRAGQAGSAKALAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVKGSRYAPNRRRFRRFIPRPRPAAPPPMVAEAPSGGTEPGSEGERAEDSGQRPRRRRPPPFFYRRRFVRGPRPPNQQQPIEGSDGVEPKETTPLEGDQQQGDERVPPPRFRPRYRRPFRPRPPQQPTTEGGDGETKPSQGPTDGSRPEPQRPRNRPYFQRRRQQPPGPRQPIAAETSAPINSGDPPTTILE
Protein: Protein adenylyltransferase SelO (EC 2.7.7.108) (Selenoprotein O homolog) (SelO) (P77649)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation). Cannot use GTP, CTP or UTP as cosubstrate. AMPylates SucA at 'Thr-405' and GrxA on 'Tyr-13'. Regulates protein S-glutathionylation levels probably by AMPylation of deglutathionylation enzymes such as GrxA. Probably involved in redox homeostasis.
Interaction partners:
- tRNA 2-selenouridine synthase
Sequence:
MTLSFVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGEALLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETAEPGAMLMRVAPSHLRFGHFEHFYYRRESEKVRQLADFAIRHYWSHLADDEDKYRLWFSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGERMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
Protein: Transcription repressor OFP18 (Ovate family protein 18) (AtOFP18) (Q9SVD5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Transcription repressor OFP16
- Transcription repressor OFP6
- Transcription repressor OFP7
- Transcription repressor OFP2
- Transcription repressor OFP5
- Transcription repressor OFP8
- Transcription repressor OFP17
- Transcription repressor OFP1
- Transcription repressor OFP4
- Transcription repressor OFP3
Sequence:
MVRKMKLPFLNKNTSSSSFSSNSSSSSSSWPWPSSHQQNLKTISSKASFIVNKPKDVYEPEPPPRSFSSSPSSSSYSSFSSTSHAIENPPEIESIENVIKGLKSSKRLIFERRGTSNSILEEATKRDDHEEEEDGLMLLSLESNDPYTDFKNSMEKMVEVHVLHHDWISLEKLLFWFLKVNVKASHRYIFAAFVDLVLNLAVGPSKDVAGEPNSDVVVEDSLSSSWPVSLYSSSDENSSTSVRFLPETSIGEKGRDVCCLSSLFELEEKIKDNIDPNDYVSS
Protein: Inner membrane protein p12 (Protein p12) (P32510)
Organism: African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV)
Subcellular location: Virion membrane {ECO:0000305|PubMed:30185597}; Single-pass membrane protein {ECO:0000305}. Note=Part of the virion inner membrane. {ECO:0000269|PubMed:30185597}.
Interaction partners:
Sequence:
MALDGSSGGGSNVETLLIVAIIVVIMAIMLYYFWWMPRQQKKCSKAEECTCNNGSCSLKTS
Protein: Uncharacterized protein, isoform C (A0A0B4K6E6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 5B, isoform A
- Mitochondrial-processing peptidase subunit beta
- Cytochrome c oxidase subunit 5B-like
Sequence:
MSSKSLFDSEEDAAQANKLSRKAKESPFMLVGEFCQFPDSESFAAVTSHGNFWLSSQLDTHISTHIYECTLRVRRGSRLILTLAMSLTSIWGHFLMSLCDITVNAV
Protein: PHD finger protein 19 (Polycomb-like protein 3) (hPCL3) (Q5T6S3)
Organism: Homo sapiens (Human)
Function: Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds histone H3 dimethylated at 'Lys-36' (H3K36me2). Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter.
Subcellular location: Nucleus {ECO:0000269|PubMed:15563832, ECO:0000269|PubMed:31959557}. Note=Localizes to chromatin as part of the PRC2 complex. {ECO:0000269|PubMed:31959557}.
Interaction partners:
- Polycomb protein SUZ12
- Elongin BC and Polycomb repressive complex 2-associated protein
- Protein Jumonji
- Histone-binding protein RBBP4
- Histone-lysine N-methyltransferase EZH2
- Metal-response element-binding transcription factor 2
- Polycomb protein EED
- Histone-lysine N-methyltransferase EZH1
- Histone H3.1t
- PHD finger protein 1
Sequence:
MENRALDPGTRDSYGATSHLPNKGALAKVKNNFKDLMSKLTEGQYVLCRWTDGLYYLGKIKRVSSSKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCNICLGKTSGPLNEILICGKCGLGYHQQCHIPIAGSADQPLLTPWFCRRCIFALAVRKGGALKKGAIARTLQAVKMVLSYQPEELEWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWFHEACTQCLNEPMMFGDRFYLFFCSVCNQGPEYIERLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWELLQLGKLTSTPVTDRGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPGKLLPDKGLLPNENSASSELRKRGKSKPGLLPHEFQQQKRRVYRRKRSKFLLEDAIPSSDFTSAWSTNHHLASIFDFTLDEIQSLKSASSGQTFFSDVDSTDAASTSGSASTSLSYDSRWTVGSRKRKLAAKAYMPLRAKRWAAELDGRCPSDSSAEGASVPERPDEGIDSHTFESISEDDSSLSHLKSSITNYFGAAGRLACGEKYQVLARRVTPEGKVQYLVEWEGTTPY
Protein: Phragmoplastin DRP1E (EC 3.6.5.-) (Dynamin-like protein 1E) (Dynamin-like protein 4) (Dynamin-like protein DLP2) (Dynamin-related protein 1E) (AtDRP1E) (Q9FNX5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Microtubule-associated force-producing protein that is targeted to the tubulo-vesicular network of the forming cell plate during cytokinesis. Also plays a major role in plasma membrane maintenance and cell wall integrity with an implication in vesicular trafficking, polar cell expansion, and other aspects of plant growth and development. Has a GTPase activity (By similarity).
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, phragmoplast. Note=Microtubule-associated and localized in the forming cell plate during cytokinesis.
Interaction partners:
- Dynamin
- Protein trichome birefringence-like 1
- GDSL esterase/lipase At3g09930
- At5g54850
Sequence:
MTTMESLIGLVNRIQRACTVLGDYGGGTGSNAFNSLWEALPTVAVVGGQSSGKSSVLESIVGRDFLPRGSGIVTRRPLVLQLHKTDDGTEEYAEFLHLPKKQFTDFALVRREIQDETDRITGKNKQISPVPIHLSIYSPNVVNLTLIDLPGLTKVAVEGQPETIAEDIESMVRTYVDKPNCIILAISPANQDIATSDAIKLAKDVDPTGERTFGVLTKLDLMDKGTNALEVLEGRSYRLQHPWVGIVNRSQADINKNVDMMLARRKEREYFDTSPDYGHLASKMGSEYLAKLLSKHLESVIRTRIPSILSLINKSIEELERELDRMGRPVAVDAGAQLYTILEMCRAFDKIFKEHLDGGRPGGDRIYGVFDNQLPAALKKLPFDRHLSLQSVKKIVSEADGYQPHLIAPEQGYRRLIEGALGYFRGPAEASVDAVHYVLKELVRKSISETEELKRFPSLQVELAAAANSSLEKFREESKKSVIRLVDMESAYLTAEFFRKLPQEIERPVTNSKNQTASPSSATLDQYGDGHFRRIASNVSAYVNMVSDTLRNTIPKACVYCQVRQAKLALLNYFYSQISKREGKQLGQLLDEDPALMDRRLECAKRLELYKKARDEIDAVAWVR
Protein: Iron-sulfur cluster biogenesis chaperone, mitochondrial (EC 3.6.4.10) (Heat shock protein SSQ1, mitochondrial) (Stress-seventy subfamily Q protein 1) (mtHSP70 homolog) (Q05931)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Assisted by the DnaJ-like co-chaperone JAC1 and the nucleotide exchange factor MGE1, it mediates ATP-dependent Fe-S cluster transfer from the scaffold proteins ISU1/ISU2 to GRX5.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:10779357, ECO:0000269|PubMed:11273703, ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}.
Interaction partners:
- GrpE protein homolog
- Iron sulfur cluster assembly protein 1, mitochondrial
- J-type co-chaperone JAC1, mitochondrial
- Frataxin homolog, mitochondrial
- Cysteine desulfurase, mitochondrial
- Iron sulfur cluster assembly protein 2, mitochondrial
- Monothiol glutaredoxin-5
- Import motor subunit, mitochondrial
- Protein ISD11
- Adrenodoxin homolog, mitochondrial
Sequence:
MLKSGRLNFLKLNINSRLLYSTNPQLTKKVIGIDLGTTNSAVAYIRDSNDKKSATIIENDEGQRTTPSIVAFDVKSSPQNKDQMKTLVGMAAKRQNAINSENTFFATKRLIGRAFNDKEVQRDMAVMPYKIVKCESNGQAYLSTSNGLIQSPSQIASILLKYLKQTSEEYLGEKVNLAVITVPAYFNDSQRQATKDAGKLAGLNVLRVINEPTAAALSFGIDDKRNNGLIAVYDLGGGTFDISILDIEDGVFEVRATNGDTHLGGEDFDNVIVNYIIDTFIHENPEITREEITKNRETMQRLKDVSERAKIDLSHVKKTFIELPFVYKSKHLRVPMTEEELDNMTLSLINRTIPPVKQALKDADIEPEDIDEVILVGGMTRMPKIRSVVKDLFGKSPNSSVNPDETVALGAAIQGGILSGEIKNVLLLDVTPLTLGIETFGGAFSPLIPRNTTVPVKKTEIFSTGVDGQAGVDIKVFQGERGLVRNNKLIGDLKLTGITPLPKGIPQIYVTFDIDADGIINVSAAEKSSGKQQSITVIPNSGLSEEEIAKLIEEANANRAQDNLIRQRLELISKADIMISDTENLFKRYEKLISSEKEYSNIVEDIKALRQAIKNFKANENDMSIDVNGIKKATDALQGRALKLFQSATKNQQNQGK