wanglab/gogpt-training-data huggingface dataset:
Protein: Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Solute carrier family 43 member 1) (Q8BSM7)
Organism: Mus musculus (Mouse)
Function: Uniport that mediates the transport of neutral amino acids such as L-leucine, L-isoleucine, L-valine, and L-phenylalanine. The transport activity is sodium ions-independent, electroneutral and mediated by a facilitated diffusion.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17322374}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:O75387}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:17322374}; Multi-pass membrane protein {ECO:0000255}. Note=Located in the apical plasma membrane of the podocyte foot processes (By similarity). Located in the plasma membrane of liver and skeletal muscle, and in the endoplasmic reticulum and in crystalline inclusions in pancreatic acinar cells (PubMed:17322374). {ECO:0000250|UniProtKB:O75387, ECO:0000269|PubMed:17322374}.
Interaction partners:
- Large neutral amino acids transporter small subunit 2
- Amino acid transporter heavy chain SLC3A2
- Large neutral amino acids transporter small subunit 1
- Y+L amino acid transporter 2
Sequence:
MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCPAENRTNTTQDEQHQWTSCDQQEKMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVPFTVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQKSPSLEEGADAFISSPDIPGTSEETPEKSVPFRKSLCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFIVTGGKERETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDAPTEGTLNENASFGDARDGASTKFTRPRYRKVQKLTNAINAFTLTNILLVGFGIACLIKNLHLQLLAFVLHTIVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLLLSFLGFLLPSYLYYYRSRLQREYATNLVDPQKVLNTSKVAT
Protein: Dynein light chain roadblock (Q22752)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR009998}.
Interaction partners:
- WD_REPEATS_REGION domain-containing protein
- DYnein Light chain
- Tctex1 domain-containing protein 2
- DYnein Light chain
- Cytoplasmic dynein 2 heavy chain 1
- Cytoplasmic dynein 2 light intermediate chain 1
- Dynein light intermediate chain
- Probable dynein light chain 2
- Dynein heavy chain, cytoplasmic
- DYnein Light chain, Axonemal p28 type
Sequence:
MSDFEETIRRLQSEKGVVGIIVVDSAGRVIHSTIDSDATQSHTAFLQQLCEKTKTSIRELDSSNDLTFLRLRTKKNEIMIAPDKDHVIMVIKDLS
Protein: Glycine cleavage system transcriptional activator (Gcv operon activator) (P0A9F6)
Organism: Escherichia coli (strain K12)
Function: Regulatory protein for the glycine cleavage system operon (gcv). Mediates activation of gcv by glycine and repression by purines. GcvA is negatively autoregulated. Binds to three sites upstream of the gcv promoter.
Subcellular location: Cytoplasm.
Interaction partners:
- Glycine cleavage system transcriptional repressor
- UPF0382 inner membrane protein YgdD
- Ribosomal RNA large subunit methyltransferase M
- Aminomethyltransferase
- HTH-type transcriptional regulator CysB
- Sulfur acceptor protein CsdE
Sequence:
MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWILAKAAAEQEKFRFRYEQ
Protein: Antitoxin VapB43 (P9WL41)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC43.
Interaction partners:
- Ribonuclease VapC43
- Ribonuclease VapC37
- Ribonuclease VapC48
- Putative antitoxin VapB7
- Ribonuclease VapC7
- Ribonuclease VapC23
Sequence:
MRTTIRIDDELYREVKAKAARSGRTVAAVLEDAVRRGLNPPKPQAAGRYRVQPSGKGGLRPGVDLSSNAALAEAMNDGVSVDAVR
Protein: Comitin (24 kDa actin-binding protein) (CABP1-related protein p24) (Q03380)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May have a role in cell motility. It has high affinity for both G-actin and F-actin. Binds to vesicle membranes via mannose residues and, by way of its interaction with actin, links these membranes to the cytoskeleton.
Subcellular location: Golgi apparatus membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Primarily on Golgi and vesicle membranes.
Interaction partners:
- Interaptin
- Centrosomin N-terminal motif 1 domain-containing protein
Sequence:
MELLRQGEHLHSTSRSTLESKCRKYKLIMQNDGNLVLYIGSLKSQSDEYCLWSSASCGKGHGPYRLSMQEDGNLVIYDSRNSAIWASGTMGHGVRGHYSMKLRSSGQIVVYDKYKQILYSSKPCTRDHLLSLPCAKPSGHPQSAYPPQQPGYGYPAQPGYPPQPGYPPQHGYPPQHGYPQQPGYY
Protein: Transcription factor Sp4 (SPR-1) (Q02446)
Organism: Homo sapiens (Human)
Function: Binds to GT and GC boxes promoters elements. Probable transcriptional activator.
Subcellular location: Nucleus.
Interaction partners:
- BLOC-3 complex member HPS4
- Gap junction alpha-5 protein
Sequence:
MSDQKKEEEEEAAAAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVAAGGGTGQVGQPAATADSGTSNGNQLVSTPTNTTTSASTMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTIEESQTPAATESEAQSSSQLQPNGMQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDQEVQPGKRLRRVACSCPNCREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
Protein: KDEL-tailed cysteine endopeptidase CEP1 (EC 3.4.22.-) (Cysteine proteinase CP56) (AtCP56) (Q9FGR9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses protease activity in vitro. Involved in the final stage of developmental programmed cell death and in intercalation of new cells. Cleaves extensins, thus probably supporting the final cell collapse. During the compatible interaction with the biotrophic powdery mildew fungus Erysiphe cruciferarum, involved in the control of late epidermal cell death that limits growth and susceptibility to the parasite. During anther development, involved in tapetal programmed cell death (PCD), leading to degeneration of tapetal cells and functional pollen formation.
Subcellular location: Endoplasmic reticulum {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:24605116}. Vacuole {ECO:0000269|PubMed:25035401}. Note=During anther development, detected as a proenzyme in precursor protease vesicles in tapetum cells and then transported to the vacuole and transformed into the mature enzyme before rupture of the vacuole. {ECO:0000269|PubMed:25035401}.
Interaction partners:
- UPF0235 protein At5g63440
- Aspartyl protease UND
- Expressed protein
- Vacuolar-processing enzyme beta-isozyme
- Precursor of CEP15
- Putative UPF0481 protein At3g02645
- Precursor of CEP8
- Precursor of CEP4
- Precursor of CEP14
- Precursor of CEP6
Sequence:
MKRFIVLALCMLMVLETTKGLDFHNKDVESENSLWELYERWRSHHTVARSLEEKAKRFNVFKHNVKHIHETNKKDKSYKLKLNKFGDMTSEEFRRTYAGSNIKHHRMFQGEKKATKSFMYANVNTLPTSVDWRKNGAVTPVKNQGQCGSCWAFSTVVAVEGINQIRTKKLTSLSEQELVDCDTNQNQGCNGGLMDLAFEFIKEKGGLTSELVYPYKASDETCDTNKENAPVVSIDGHEDVPKNSEDDLMKAVANQPVSVAIDAGGSDFQFYSEGVFTGRCGTELNHGVAVVGYGTTIDGTKYWIVKNSWGEEWGEKGYIRMQRGIRHKEGLCGIAMEASYPLKNSNTNPSRLSLDSLKDEL
Protein: DNA repair endonuclease UVH1 (EC 3.1.-.-) (DNA excision repair protein XP-F homolog) (Ultraviolet hypersensitive 1) (AtRAD1) (Q9LKI5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Seems to be involved in nucleotide excision repair (NER) of damaged DNA (dark repair mechanism). Involved in repair of UV light, and probably oxidative damage. The UVH1/RAD1-ERCC1/RAD10 complex may act as an endonuclease making DNA incision 5' to the lesion site. In vitro, is implicated in double strand breaks (DSBs) repair and is required for homologous recombination in the presence of non-homologous overhangs. May mediate the induction of a DNA-damage sensitive cell-cycle checkpoint during the G2 phase.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DNA excision repair protein ERCC-1
- AT5G65740 protein
- DNA repair protein UVH3
- Crossover junction endonuclease MUS81
- General transcription and DNA repair factor IIH helicase subunit XPD
- Cell cycle checkpoint control protein family
- Checkpoint protein
- AT5G19950 protein
- DNA topoisomerase 3-alpha
- Crossover junction endonuclease MUS81
Sequence:
MALKYHQQIISDLLEDSNGGLLILSSGLSLAKLIASLLILHSPSQGTLLLLLSPAAQSLKSRIIHYISSLDSPTPTEITADLPANQRYSLYTSGSPFFITPRILIVDLLTQRIPVSSLAGIFILNAHSISETSTEAFIIRIVKSLNSSAYIRAFSDRPQAMVSGFAKTERTMRALFLRKIHLWPRFQLDVSQELEREPPEVVDIRVSMSNYMVGIQKAIIEVMDACLKEMKKTNKVDVDDLTVESGLFKSFDEIVRRQLDPIWHTLGKRTKQLVSDLKTLRKLLDYLVRYDAVSFLKFLDTLRVSESYRSVWLFAESSYKIFDFAKKRVYRLVKASDVKSKEHVKNKSGKKRNSKGETDSVEAVGGETATNVATGVVVEEVLEEAPKWKVLREILEETQEERLKQAFSEEDNSDNNGIVLVACKDERSCMQLEDCITNNPQKVMREEWEMYLLSKIELRSMQTPQKKKQKTPKGFGILDGVVPVTTIQNSEGSSVGRQEHEALMAAASSIRKLGKTTDMASGNNNPEPHVDKASCTKGKAKKDPTSLRRSLRSCNKKTTNSKPEILPGPENEEKANEASTSAPQEANAVRPSGAKKLPPVHFYALESDQPILDILKPSVIIVYHPDMGFVRELEVYKAENPLRKLKVYFIFYDESTEVQKFEASIRRENEAFESLIRQKSSMIIPVDQDGLCMGSNSSTEFPASSTQNSLTRKAGGRKELEKETQVIVDMREFMSSLPNVLHQKGMKIIPVTLEVGDYILSPSICVERKSIQDLFQSFTSGRLFHQVEMMSRYYRIPVLLIEFSQDKSFSFQSSSDISDDVTPYNIISKLSLLVLHFPRLRLLWSRSLHATAEIFTTLKSNQDEPDETRAIRVGVPSEEGIIENDIRAENYNTSAVEFLRRLPGVSDANYRSIMEKCKSLAELASLPVETLAELMGGHKVAKSLREFLDAKYPTLL
Protein: Shaggy-related protein kinase GSK4 (EC 2.7.11.1) (Glycogen synthase kinase3-like protein 4) (OsGSK4) (Shaggy-related protein kinase etha homolog) (OsKETHA) (SKETHA) (Q5Z7J0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Probable serine-threonine kinase that may regulate brassinosteroid signaling.
Interaction partners:
- protein-serine/threonine phosphatase
- Os01g0185400 protein
- Shaggy-related protein kinase GSK1
- non-specific serine/threonine protein kinase
- Protein BZR1 homolog 1
- Os04g0280200 protein
- Phosphoribulokinase
- Uridine kinase
- uracil phosphoribosyltransferase
- Uridine kinase
Sequence:
MAAMPGGPDLAGAGGAVAVAVDAMQVDDPPRASAEEKHGPTIMGGNDPVTGHIISTTIGGKNDEPKRTISYMAERVVGTGSFGVVFQAKCLETGETVAIKKVLQDKRYKNRELQIMRSMDHCNVISLKHCFFSTTSRDELFLNLVMEFVPESLYRVLKHYKDMKQRMPLIYVKLYMYQIFRGLAYIHTVPGVCHRDIKPQNILVDPLTHQVKVCDFGSAKMLIKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGESAVDQLVEIIKVLGTPTREEIRCMNPNYTEFKFPQIKACPWHKIFHKRMPPEAIDLVSRLLQYSPNLRCTALEACAHSFFDELREPHAKLPNGRPFPPLFNFKQELANTHPELVSRLLPEHAQRHSGF
Protein: ATP synthase subunit delta (ATP synthase F(1) sector subunit delta) (F-type ATPase subunit delta) (F-ATPase subunit delta) (P27180)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
Subcellular location: Cellular thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01416}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01416}.
Interaction partners:
- ATP synthase subunit b
- ATP synthase epsilon chain
- ATP synthase gamma chain
- ATP synthase subunit a
- ATP synthase subunit b'
- ATP synthase subunit c
- ATP synthase subunit alpha
- ATP synthase subunit beta
- Hydrogenase subunit
- ATP synthase protein I
Sequence:
MKGSLYSSKIAEPYAQALIGLAQQQNLTEVFGDNLRSLLTLLQDSPDLSAVLSSPVVKDEDKKSVLRSVLGDGGNGYLLNFLMLLVDKRRIVFLEAICEQYLALLRQFTNTVLAEVTSALKLTDAQKDQVKERVKQLTGAQAVELETKVDGDILGGIVIKVGSQVFDSSLRGQLRRVGLSLGTAL
Protein: peptide-methionine (S)-S-oxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Protein-methionine-S-oxide reductase) (Q57YH5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- MsrB domain-containing protein
- Nucleoside diphosphate kinase-like domain-containing protein
- Flagellar attachment zone protein 1 conserved domain-containing protein
- Thioredoxin
- Glutaredoxin, putative
- Glutaredoxin, putative
Sequence:
MNPNAVATFAAGCFWGTEHFFVRQFGAALISHKVGFMGGKELPEMNYQLVKKGDTGHAEVLQVTYNTNELTYDALLNFFFRMHNPTTLNRQEGDVGTQYRSTIFYHNEEQRNEAESFIEKLNGGDEKLRENIVKAFGSSAKVVTTLERASRFYPAEDYHQNYLEENPNGYCAHRLYW
Protein: K-stimulated pyrophosphate-energized sodium pump protein (F4JXE8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEKVSSPSSSFSRRSAYLEALTQEIKKKLTRAVVSPAQTRNLLQDLFADIALEVDDRAKDVILSKEEDLITSDEADADGPLCFFDVLADYYVKVSERGKDILDLMVQLWSQSFASHIFSLLFHKWLFEVELDNQEILLRYSSALVQGATNVFWIDIQTNTRRFQSLFRYLLEEVALEQIRLKKIPIQAQRELYLLLSRFIFFYNSVDKLDSFLRNFPEFPNAFLIGGPGDFLVIELTDQLQKLKVEPVLLHYLSQMKILQGMELRMTTSTRLKACLYSFTSPGGPMYPTRAVRHAAWDALDSLFPVGRYPRHLISLFFRLLYPWYWPSSCWNFVVSCIKAVLYSIVRLIFSRREKPRQS
Protein: DNA polymerase interacting tetratricopeptide repeat-containing, protein of 47 kDa (DNA polymerase interacting TPR-containing, protein of 47 kDa) (Tetratricopeptide repeat protein 4 homolog) (TPR repeat protein 4 homolog) (A1Z6M6)
Organism: Drosophila melanogaster (Fruit fly)
Function: May act as a co-chaperone for HSP83.
Subcellular location: Nucleus {ECO:0000269|PubMed:11493638}. Nucleus, nucleoplasm {ECO:0000269|PubMed:11493638}. Cytoplasm {ECO:0000269|PubMed:11493638}. Note=In embryos prior to cellularisation, found in the nucleus and cytoplasm but after cellularisation seen predominantly in the nucleus. {ECO:0000269|PubMed:11493638}.
Interaction partners:
- Protein HGH1 homolog
- LD24471p
- Heat shock protein 83
- Stress-induced-phosphoprotein 1
- Large ribosomal subunit protein mL43
Sequence:
MKQMAAQKAWTDEERLELAAQLDAELDAFIDGLEKKRYEEGWPEDRWQEEMDKHPFFMKRAPQPGDDVHPMFEGLQKLKYDPEENTRDELALNYKEDGNFYMKHKKFRMAIYSFTEGIKTKTDNPDVLAVLYNNRSAAHFFIKNYRSSLSDAQRALFYKPDYTKARWRSAQCAYELERFDLCTQMCEELLEVDVDNEVAIALLHKNKMKKLEIERNQRKEAAEAKRRLTRFHRLRDAIEQRAIKFDDQKVGKKDVLSEELLYPKFLPLEDHPVHLDEDGSTLIWPAAFSYPEFLYSDFYQQLPETTTMRDCLATLLTEKLPYDKAHNYRLGNVHVYYENRKVGCVHKVDEEKQLAEIIAEKGFFVSGGALLFYVVHKDSRVEQEFINERRRPMVYS
Protein: Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain] (P49290)
Organism: Mus musculus (Mouse)
Function: Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils.
Subcellular location: Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.
Interaction partners:
- Bone marrow proteoglycan
- Proteoglycan 3
- Interleukin-5
- Interleukin-4
Sequence:
MMQQLLALVGALATLILTQHAEGTAPASPSPVEISVLRDCIAEAKLLVDTAYNHTQKSIMQRLRSGSASPMDLLAYFKQPVAATRRVVQAADYMHVALGLLEERLQPRGSRPFNATDVLTEPQLRLLSQASGCALQDQAERCSNKYRTITGRCNNKKHPWLGASNQALARWLPAEYEDHRSLPFGWTPGKRRNGFLLPLVRDVSNQIVRFPSKKLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFSMGVDCEKTCAQLPPCFPIKIPRNDPRIKNQRDCIPFFRSAPACPQNRNKVRNQINALTSFVDASMVYGSEVTLALRLRNRTNFLGLLATNQRFQDNGRALLPFDNLHEDPCLLTNRSARIPCFLAGDTRSSETPKLTALHTLFVREHNRLAAELRRLNPHWSGDKLYNEARKIVGAMVQIITYRDFLPLVLGRARIRRTLGPYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSVFFASWRIIHEGGIDPILRGLMATPAKLNRQDSMLVDELRDKLFQQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLRLYKTPDNIDIWVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKWGVFTKRQRKALRRISLSRIVCDNTGITTVSRDIFRANIYPQGFVSCSRIPKLNLSAWRGK
Protein: Voltage-dependent anion-selective channel (DmVDAC) (Porin) (Q94920)
Organism: Drosophila melanogaster (Fruit fly)
Function: Forms a channel through the mitochondrial outer membrane and also the plasma membrane (By similarity). The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis (By similarity). It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (By similarity). The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). In depolarized mitochondria, acts downstream of park to promote mitophagy or prevent apoptosis; polyubiquitination by park promotes mitophagy, while monoubiquitination by park decreases mitochondrial calcium influx which ultimately inhibits apoptosis.
Subcellular location: Mitochondrion outer membrane.
Interaction partners:
- Inositol 1,4,5-trisphosphate receptor
- Transmembrane GTPase Marf
- Cytochrome c-2
- LD34461p
- Serine/threonine-protein kinase Pink1, mitochondrial
- Cytochrome c-1
- E3 ubiquitin-protein ligase parkin
- ATP synthase subunit alpha, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- ADP,ATP carrier protein
Sequence:
MAPPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA
Protein: Myosin-binding protein H-like (Q5FW53)
Organism: Mus musculus (Mouse)
Function: Myosin-binding protein which plays a role in cardiac function. Seems to regulate conduction in the atria and ventricular conduction systems.
Subcellular location: Cytoplasm, myofibril, sarcomere {ECO:0000269|PubMed:28778945}.
Interaction partners:
- Myosin regulatory light chain 2, atrial isoform
- Proline/serine-rich coiled-coil protein 1
- Cadherin EGF LAG seven-pass G-type receptor 2
- Natriuretic peptides A
Sequence:
METATTLEIASCSQRQVEAAADPADAKGPRTSHQQEAGSPSLQLLPSIEEHPKIWLPRALKQTYIRKAGETVNLLIPIQGKPKPQTTWTHNGCALDSSRVSVRNGEHDSILFIREAQRTDSGCYQLCVQLGGLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSGLWFTVLERYHRTSCVVSNLIVGNSYAFRVFAENQCGLSDTAPVTADLAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPRPKIIWLKNKMDLQGNPKYRALSQLGICSLEIRKPSPFDGGIYTCKAINALGEASVDCRVDVKAPH
Protein: Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) (Q9UBM8)
Organism: Homo sapiens (Human)
Function: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
- Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
Sequence:
MFKFHQMKHIFEILDKMRCLRKRSTVSFLGVLVIFLLFMNLYIEDSYVLEGDKQLIRETSTHQLNSERYVHTFKDLSNFSGAINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLETIKSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYPILDGLKRNYNDPEDRVKFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSKNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASLYTNMNVFENYEASKAYSSVDEYFWGKPPSTGDVFVIVFENPIIIKKIKVNTGTEDRQNDILHHGALDVGENVMPSKQRRQCSTYLRLGEFKNGNFEMSGVNQKIPFDIHCMRIYVTKTQKEWLIIRSISIWTS
Protein: 3',5'-cyclic-nucleotide phosphodiesterase regA (PDEase regA) (EC 3.1.4.53) (Phosphodiesterase 2) (DdPDE2) (Response regulator protein A) (cAMP-specific 3',5'-cAMP phosphodiesterase 2) (Q23917)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Phosphodiesterase specific for cAMP. Involved in the degradation of intracellular cAMP. Morphological suppressor of tagB. Phosphorelay protein that accepts phosphate from rdeA or supplies phosphate from regA; depending on the relative concentration of the phosphodonor proteins.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:12429832, ECO:0000269|PubMed:17040207}.
Interaction partners:
- cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase A
- 3',5'-cyclic-AMP phosphodiesterase 4
- AMP deaminase
- Adenylate kinase
- Probable adenylate kinase B
- Adenosine kinase
- Probable adenine phosphoribosyltransferase
- Adenylosuccinate lyase
- Cytosolic purine 5'-nucleotidase
- Adenylate kinase isoenzyme 6 homolog
Sequence:
MNNKQEEIDQFLSSTSTSPSPSSSSSPSNNDSTSLKSMISGIENLNVHSKGNDNKNNNNNNNNNNSNNNEKQKDIVSLENNSSSNNTTTTTTTTTTSNHNSNNNSNNNNNNINNNNINNNNYEPLVNGHNNGFGDKLNDQPSPSSHRVSDFSDEYSPSKVRILVADDDDVQRKILNNLLKKFHYNVTLVPNGEIAWEYINKGQQKYDLVLTDVMMPHITGFDLLQRINDHPVHRHIPVILMSGTAVDYKYANDTIKIGGQDFLTKPIAKELLKKKIDTVLQSIWQRRKEEEYKATLAQEREKGNKLAKEMELKEHEIEELTKKVSKMSSISKEAMESPLVSVTRNIEELLKQSSWSHYESEIKEKLSSILKELGSSNIYRPSFEKLIKNDSVDPVTKSFLVSEFSSTTSRRNSIPTFPQTTYNRDTKEVIKGWEFDVFKYSEDDLMPLLVDMFENFQLPEIFKIPIEKLQRFIMTVNALYRKNNRYHNFTHAFDVTQTVYTFLTSFNAAQYLTHLDIFALLISCMCHDLNHPGFNNTFQVNAQTELSLEYNDISVLENHHAMLTFKILRNSECNILEGLNEDQYKELRRSVVQLILATDMQNHFEHTNKFQHHLNNLPFDRNKKEDRQMILNFLIKCGDISNIARPWHLNFEWSLRVSDEFFQQSHYETICGYPVTPFMDKTKTTRARIAADFIDFVASPLFQSMAKFLKESQFLLKVISKNRENWQAYMELQKEGKCNDDDLQFMEDPTILVKSKLPKIDEEENRDKVSSSSSSSTAPLTSTSSSNNETSSS
Protein: Nicotinic acetylcholine receptor subunit Dalpha7 (Q86MN7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Interaction partners:
Sequence:
MSFPQPHSLPEATANGGRMLVYGLGLLIMIPACAAGPHEKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDEAGGDISSFITNGEWDLLGVPGKRNEIYYNCCPEPYIDITFAILIRRKTLYYFFNLIVPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGKYFNCIMFMVASSVVSTILVLNYHHRNPDTHEMSEWIRVIFLYWLPCILRMQRPGQVGYECPPPPSSSSSSASGEKKQQIQNVELKERSSKSLLANVLDIDDDFRCNHRCASATLPHQPTYYRTMYRQGDDGSVGPVGPAGPVVDGRLHEAISHTCLTSSAEYELALILKELRWITEQLKKEDETSDITRDWKFAAMVVDRLCLIIFTLFTIIATLAVLFSAPHFIVSGVRG
Protein: Ubiquitin-conjugating enzyme E2, putative (EC 6.3.2.19) (Q382E3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- NEDD8-activating enzyme E1 catalytic subunit
- Ubiquitin-like modifier-activating enzyme ATG7
- Polyubiquitin, putative
- Ubiquitin-conjugating enzyme, putative
- Ubiquitin-conjugating enzyme, putative
- Ubiquitin-like modifier-activating enzyme 5
- Ubiquitin-activating enzyme E1, putative
- Ubiquitin-activating enzyme E1, putative
- Ubiquitin-conjugating enzyme E2, putative
- Ubiquitin-conjugating enzyme E2, putative
Sequence:
MSTDRSSRRKEMDFMKLMNGPRKVHPSDSVSEFWVEFCGPEGTPYEDGVWYIHVQLPAEYPFKSPSIGFSNRIFHPNVDESSGSVCLDVINQTWTPMYELHNIFDVFLPQLLRYPNASDPLNSAAASKLIHDPIGYVTFVQDHVAEYATRRVALQSIPSGFRPQGNGASSAAEVKNNISSEEDSTATPKGLTEITTPHVVSEGGEEEEYEPDAIDI
Protein: Zinc finger CCHC domain-containing protein 13 (Q8WW36)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSSKDFFACGHSGHWARGCPRGGAGGRRGGGHGRGSQCGSTTLSYTCYCCGESGRNAKNCVLLGNICYNCGRSGHIAKDCKDPKRERRQHCYTCGRLGHLARDCDRQKEQKCYSCGKLGHIQKDCAQVKCYRCGEIGHVAINCSKARPGQLLPLRQIPTSSQGMSQ
Protein: Transmembrane protein 50A (Small membrane protein 1) (Q9CXL1)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Leptin receptor gene-related protein
- Leptin receptor overlapping transcript-like 1
Sequence:
MSGFLEGSRCSECMDWGEKRNTIASIAAGVLFFTGWWIIIDAAVMYPRMDQFNHSYHTCGVIATIAFLMINAVSNGQVRGDSYSEGCLGQTGARIWLFIGFMLAFGSLIASMWILFGGYVAKEKDVVYPGIAVFFQNAFIFFGGLVFKFGRTEDLWQ