wanglab/gogpt-training-data huggingface dataset:
Protein: Cytochrome P450 714D1 (EC 1.14.-.-) (Protein ELONGATED UPPERMOST INTERNODE 1) (EUI1) (Q5KQH7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the 16alpha,17-epoxidation on non-13-hydroxylated gibberellins (GAs), including GA4, GA9, and GA12. No activity with GA1, GA20, GA53 or ent-kaurenoic acid. Reduces the biological activity of GAs.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16399803}; Single-pass type III membrane protein {ECO:0000269|PubMed:16399803}.
Interaction partners:
- Nitrate reductase 1
- Nitrate reductase
- Nitrate reductase
- Probable 5'-adenylylsulfate reductase 1, chloroplastic
- 4-coumarate--CoA ligase-like 9
- 4-coumarate--CoA ligase 2
- Cytochrome P450 98A1, putative
- Cytochrome P450 73A33
- Chalcone synthase 1
- Cytochrome P450 73A33
Sequence:
MESFFVFFTAAALPVVVAAAVIAGLCITAAWLARPRRVAEVFRRQGIDGPPPSSFLAGNLPEMKARVAAAASAAAPTADGEETASAGGGGGGRDFEKDGFDDYCTRIFPYFHKWRKAYGETYLYWLRRRPALYVTDPELIGEIGRCVSLDMGKPKYLQKGQEPLFGGGVLKANGACWARQRKVIAPEFYMARVRAMVQLMVDAAQPLIASWESRIDAAGGAAAAEVVVDGDLRSFSFDVISRACFGSDYSRGREIFLRLRELSGLMSETSVIFSIPSLRHLPTGKNRRIWRLTGEIRSLIMELVRERRCAARAAREHGGKAAPPSPPERDFLGSIIENSGGQPRPDDFVVDNCKNIYFAGHETSAVTATWCLMLLAAHPEWQDRARAEVLEVCGGDGAAAPAAPDFDMVSRMRTVGMVVQETLRLFPPSSFVVRETFRDMQLGRLLAPKGTYLFVPVSTMHHDVAAWGPTARLFDPSRFRDGVAAACKHPQASFMPFGLGARTCLGQNLALVEVKTLVAVVLARFEFTLSPEYRHSPAFRLIIEPEFGLRLRIRRAGGQDATSQVDTSTAPVHSSHN
Protein: Syntaxin of plants 73 (F4JEA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGVIDLITRVDSICKKYEKYDINRQRDANVSGDDAFSRLYSAVEYALETVLQKTEDLSSETNKAKAVAMNAEIRRTKARLLEGIPKLQRLSLKKVKGLSKEELDARNDLVLSLRDKIEAIPESSAPVVGGWEASTSYSNIRFDTNVSDDRIGSEYFQPTGESDQFKQEYEMKRIKQDQGLDYIAEGLDTLKNMAQDINEELDRQEPLMDEIDTKIDKAATDLKSTNVRLKDTVTKLRSSRNFCIDIILLCILLGIAAFIYNSVK
Protein: Protein downstream neighbor of son homolog (Protein humpty dumpty) (Q9VNA8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Essential for DNA amplification in the ovary and required for cell proliferation during development.
Subcellular location: Nucleus {ECO:0000269|PubMed:15854909}.
Interaction partners:
- Origin recognition complex subunit 1
- DNA primase large subunit
- DNA replication licensing factor Mcm2
- Trifunctional purine biosynthetic protein adenosine-3
- Replication factor C subunit 2
- Histone H3-like centromeric protein cid
- DNA polymerase delta subunit 2
Sequence:
MSTEASVASKWTRPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKSKLLEAKLAQKRKNPFAKSTADAKKLRVDPQLADLEPVVTASSCFVRETPTRPAPAKFVLQKYDPQAFAKLFQHPQINAEDEDDAELAARQKHTAHLPVDWSLKTRARFFCPTELPAIQLKTSQLASGLTSFVRCMDPQRTESTLDISDATRFNQCNYYWQHPHLPWLTLYPRTAKENVGVVVGERERKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRPESHALVTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQEDEDDDEDWLESLGVDERELRRIQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNAKSAISTVGRLAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGVDYFSIDIKGLILPTFLPSVAELLSETRQMFSSTLASSINTLAFSKATQKLLETPETPQSDAEGEDAAGQVFGEQNLSECGLLPAVVGSICRTGQHAVGLLERVCYQRDEGYAWS
Protein: PRKR-like endoplasmic reticulum kinase (B8JI14)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
Interaction partners:
- Cyclic AMP-dependent transcription factor ATF-4
- Eukaryotic translation initiation factor 2 subunit 1
- Eukaryotic translation initiation factor 2 subunit 1
- Immunoglobulin binding protein
- Nuclear factor
- Cyclic AMP-dependent transcription factor ATF-4
- X-box-binding protein 1
- Activating transcription factor 6
- Endoplasmin
Sequence:
MERGFQFGNVCISLLLLLVLRTLTATLQTQSLSEREVEVAPTPNTEAAEHAAVMERPLDNVGGALGIGEVTVEDDDYGSTGDSDEPSGDTDANFHKHRRALVIISTLDGRIAALDPLNQGRKQWDLDVGSGCLVSSSLSKPEIFGNKMFIPSLDGALFQWNRDRESMEAVSFSVESLLDSSYRIGEDTVLVGGKSLTTYGLGAYSGKLKYICSAVGCSRWGDEEGEPEDVLLLQRTQKTVRAVRPRNGFEKWNFSVGNFELKFVPEIQSKLNFLEGEAPSGETWREVRREAQRVIQEETDAQTKNHAKMHPNSAHTQVEGLDLVIKVSVPDWKVMAFSTKPEGQLIWEHQFCTPIASAWLVGGGKVTPISLFDDTSYNSQTETETQEDDDIMEEARGATESSVYLGMFQGQLYLQSSVRISEKFPSKSKALNGWGGDTDMMPPPTVKWKPLIHSPSRTPVLVGSEEFDKCLNNDKFSHEEYSNGALSILQYPYDNGYYFPYSPRYRNRRDETAVSVLLKKDGEGSQVRRKDPVLLLPWWKEILGTIFFCIAATTYIVRKFFHPPTTYSRQRKESETQCQTDTKFEADVTEPKEVVVTDMRPCEYVSRYLTDFEPVQCLGRGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIIRYFNAWQESPPQGWQEDMDKRWLKDASTADWLLSSPEHMEAFSVKVPVATPSPVDSSCMCAAGGDTSVCVGDQVCVEGLGPDSMMSERDSQADPDAIMEVSDSPHSFELCPPRTVAHGDCTSSSFDIVFEDSGCEHQDNDSDLSGSTPVPPVCLSQSGSKPQRSTSTGPPISLPSRPTTLSLAPSTPCPVVRPLLTPKVYLYIQMQLCRKENLKDWMAQRCLPELREHTQCLDIFLQIAEAVDFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQEEDDEELSTLTPMPIYARHTGQVGTKLYMSPEQLSGNSYSHKVDIYSLGLILFELLCPFRTQMERVRTLTEVRALQFPAAFCKANILEAQMVRCMLSRVPAERPEASEITEAPLFQELEVPCRIRQRTRTYSASSAGRPSRQISSSN
Protein: BZIP domain-containing protein (F6SWN3)
Organism: Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVNCFSLLVNDISYKDDDQQNKDFQQINESCDTVNAIMHGGESFQHHRNRTESIDSFQSIVSPSSVTLEQNFHFPPGVKDEFPDDGFPYSDVPDVLSRPPPMTRQYSIGTVIDVISQHDINDISDVKITSSNRRQSEPVAITGTYKVERIHDNDAGFPVGGNPSYVTMQQQWSPLSSNYSTSPDPPFENYQGSPGSCHTPQYDQSTNTILAMSPPDHQMYQQNWEPPSYPITHNPTLPHTITHNPTLPQPTTCPTLSTINFNQCGLQEVTDTNSLIPILHELDKIDRRRIRNNEACKKSRMRRKQRKMDKEREAERLAAQNLHLKRKISMLQSECDKIRRQVLQARQ
Protein: Glutamate receptor 3.3 (AtGLR3.3) (Glutamate receptor-like protein 3.3) (Ligand-gated ion channel 3.3) (Q9C8E7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Glutamate-gated receptor that probably acts as non-selective cation channel, at least in roots and hypocotyls (Probable). Can be triggered by Ala, Asn, Cys, Glu, Gly, Ser and glutathione (a tripeptide consisting of Glu-Gly-Cys). Mediates leaf-to-leaf wound signaling. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. Contributes to pathogen-associated molecular patterns (PAMP) elicitor-mediated resistance. Partially involved in free cytosolic calcium variations, nitric oxide (NO) production, reactive oxygen species (ROS) production and expression of defense-related genes in response to oligogalacturonide elicitors. Inovlved in resistance against Hyaloperonospora arabidopsidis. Required for glutathione-induced defense responses, and innate immunity responses against the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000. Required for the transmission of wound-induced, phloem-propagated action potential to neighbor leaves.
Subcellular location: Cell membrane {ECO:0000269|PubMed:23590882}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the plasma membrane. {ECO:0000269|PubMed:23590882}.
Interaction partners:
- Two pore calcium channel protein 1
- Putative cyclic nucleotide-gated ion channel 19
- Probable cyclic nucleotide-gated ion channel 6
- Cyclic nucleotide-gated ion channel 4
- Probable cyclic nucleotide-gated ion channel 20, chloroplastic
- Mediator of RNA polymerase II transcription subunit 14
Sequence:
MKQLWTFFFLSFLCSGLFRRTHSEKPKVVKIGSIFSFDSVIGKVAKIAIDEAVKDVNSNPDILSGTKFSVSMQNSNCSGFMGMVEALRFMEKDIVGIIGPQCSVVAHMISHMANELRVPLLSFAVTDPVMSPLQFPYFIRTTQSDLYQMDAIASIVDFYGWKEVIAVFVDDDFGRNGVAALNDKLASRRLRITYKAGLHPDTAVNKNEIMNMLIKIMLLQPRIVVIHVYSELGFAVFKEAKYLGMMGNGYVWIATDWLSTNLDSSSPLPAERLETIQGVLVLRPHTPDSDFKREFFKRWRKMSGASLALNTYGLYAYDSVMLLARGLDKFFKDGGNISFSNHSMLNTLGKSGNLNLEAMTVFDGGEALLKDILGTRMVGLTGQLQFTPDRSRTRPAYDIINVAGTGVRQIGYWSNHSGLSTVLPELLYTKEKPNMSTSPKLKHVIWPGETFTKPRGWVFSNNGKELKIGVPLRVSYKEFVSQIRGTENMFKGFCIDVFTAAVNLLPYAVPVKFIPYGNGKENPSYTHMVEMITTGNFDGVVGDVAIVTNRTKIVDFTQPYAASGLVVVAPFKKLNSGAWAFLRPFNRLMWAVTGCCFLFVGIVVWILEHRTNDEFRGPPKRQCVTILWFSFSTMFFAHRENTVSTLGRLVLIIWLFVVLIINSSYTASLTSILTVQQLSSPIKGIESLRERDDPIGYQVGSFAESYLRNELNISESRLVPLGTPEAYAKALKDGPSKGGVAAIVDERPYVELFLSSNCAYRIVGQEFTKSGWGFAFPRDSPLAIDLSTAILELAENGDLQRIHDKWLMKNACTLENAELESDRLHLKSFWGLFLICGVACLLALFLYFVQIIRQLYKKPTDDAIARDQQQNHDSSSMRSTRLQRFLSLMDEKEESKHESKKRKIDGSMNDTSGSTRSRGFDRERSFNSVNPLD
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Q5LJA9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
ARGGSGRCVARAMTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKDGFSPCCPGWSQTPELKPSACLDLPKWYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK
Protein: DNA polymerase I-like protein B (Q8MWB4)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MRLNSCWIRRVHRGIAQSNLRCVSTFAALVKVQEALKSSKPFADDAKGFAEFFRVPCLPGVGAQESVRRHYDRVLRDLKQQKDSYVMRQQGQDERVNEELPIFLVSYDTGSKNFYLFSVEKDCNAVRFPADGESDVSGLADELMQYTRGMTQAIMIPIVADEEERGALAPHLTRLSGELKRCGIIPVLSVDSLEIIKTLDPQQSPVRIVTKGRGKHASEPLTEEWFRAHWVHLRTLVFKSSEEDPIITLNRLVAPRFTIYVIHLVRAGSRGLNVALYEPLQKKRYGAKGMLSDVLGCLLERQAKQVIFLPTNRTDRPTLLRCRTALTKMGRTCYLVFPSEIGEKYRGVYQSDPARYWSSLCEVKGSLDADFSFEVYATVGNNIRTQQYKRTRENLLEKQASLSSENNMPAVTNSEVEKWLRVLSLDKRVSCEKAQMRKYKKYLVIAFMATEFAAYTRPANPHAPANYVVATSIMDYQQQVVEPWTKYSSRGEFKLPSLEGFDVIVCHDVKHFVLLIWDDPELRRFLKRGGRVWCTMFAEYLLDAQRCQSGSNSLHDVAMKYGILTPQSSVLGLSTPDLPIAFIQHYLVAAVDAISRVFQEQLKKACGNSQLICVAHRMDSLLAMASIEKAGIHIDSKEATLQAQAIRNRLLAIDKSLSLYAPDEIPLDMQRFFDWTSLQHLQAYFFGGSITLGYTDISRDSSTWTAHLIHLCHKYGNLGLMSADVHLQRFASERGLRGAGRLPQRVARFFDADGSSRRRKYRLVVFDIESTGLNTATDAIIEVAAFDPVEGTSFSSLVNPQRPIPPQSTAIHHITDSMVQGAPRLSEVTQAFARYLRLSEGQRDEDEVTILIGHNVFALDEPLLRRAFRSESVDTENLLFCDSLTILKGLKQELQGSKKDSKFDRGVLDILTNSLRLSSLVEGLRVEADGELHRADTDAKMLWFVLVNAFGIGGKDAVKQRDEVLSHAVRTLVLYPGVGCFLPQERRKDCVTVQLPGVCFKAIKEKRTIEQLRKRHLDEATFVVLQRHKLEVAGLLLQKLQLERGSANFLHSGTDGRLSILHSDNKVRQYIDLTATTTSRTTSSYPSCQNIPKDDKSSLRHLFVSRFGEKGRCVEIDYSQLEIVVMAVLCEDERLVSDLNQGVDFHVKRASFFSGISYDEIYNGYKRGEAKFLKLRKVAKTFSFQRLYGAGVPLLHKTTGIPVQDLQECIRREEEEYPGISRFHRLARTVALRANNPGLPTHFIVELPTGLRVCYKTRDVVLNLPPVKNYPIQSFGAELAQMMIGRVFRQFVRKSFYGQKAFMINFVHDSLWLDCHMSVLEECVHETRTIMEEVDTYVAKTFPGVKLKVPLKVSVDCGVDMCAMESVKDDFSALASQQRSKSSELDALIPELSKEVTDSVEITV
Protein: Myeloperoxidase (Q90XS6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MNLPTFLFVVGCCCALSVGAEEESPGRPFILDSIEEAKKIVDAAYKYSRDESLARVRKDVIKPSDKLRLLKQPARKTREAVRAADYMAQTLRLISEKAHHVHKRSINATNLLTQDELQTITRMTGCEAQTRPPSCRTTPLINKYRTASGVCNNRKNPLLGASNTPFARWLPAQYEDAVSQPKGWDPNKLYNGAALPMVRLVSNRILATADADIESDHDFTFMLTIFGQWVDHDLTFTPFSPSIRSFSNGIDCENSCERSEPCFPISAPPGDQRLRPNTCLPVFRSAPTCGSGHTAYMFGEVPNVREQINTLTAYLDAGQVYGSEDGLAKELRDLTNDGGLLRVNNRFKDNGRELLPFTSVNTNLCATRQKILNDSTLTEVPCFIAGDARVDENPALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVGPDAYNRHLGPYPGYNENVDPTIANVFATAAFRFAHLTIQPFIFRLDENYKNHPQFPSVPLYEAFFSPWRVIFEGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSHIALDLASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTKLARKLIELYGTPENIDVWLGGVAEPFAPGGRVGSLFACLISRQFQKIRDGDRLWFESNGVFTTKQKTALASVSMARIICDNTGILKVPRDPFRFRSPASFVNCGNIPAFDLEPWKETGDGGINISDIGNEIEIPSQDLPDPGDLQENVVHRV
Protein: Palmitoyltransferase swf1 (EC 2.3.1.225) (O60069)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- t-SNARE affecting a late Golgi compartment protein 1
- Large ribosomal subunit protein eL19B
- Vacuolar protein 8
- Palmitoyltransferase akr1
Sequence:
MDFFYKYLALVAIASLMVFILLFGQIPKLKYTVIGKLNRFFMVTIPYHLHVLDSRYADGRCSAAMRSLSNYVLYKNNPLVVFLYLALITIGIASFFIYGSSLTQKFSIIDWISVLTSVLLPYISLYIAAKSNPGKIDLKNWNEASRRFPYDYKIFFPNKCSTCKFEKPARSKHCRLCNICVEKFDHHCIWINNCVGLNNARYFFLFLLCTIQLLFHSILRLGYHFNALRDMRQYPSFLRSWWFAIKSEGELGSVFLISLICSVLVLCLLGYEFFLVYAGYTTNESEKWSDLAHLVKNRKVYMYYENGSQLLALDKDASNDAILVTSMSQIDNIYDNGFYNNFFSLVFPYRHLYSTT
Protein: mitochondrial processing peptidase (EC 3.4.24.64) (Beta-MPP) (A0A1D8PCY8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Alpha-MPP
- Cytochrome b-c1 complex catalytic subunit, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome b-c1 complex subunit 7, mitochondrial
- Cytochrome c oxidase subunit 6, mitochondrial
- NAD-dependent epimerase/dehydratase domain-containing protein
- Cytochrome b-c1 complex subunit 9, mitochondrial
- Cytochrome b-c1 complex subunit 8, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
Sequence:
MFKRLSALKKYNGGIKYRGFNTAAVPSPTYQTSILPNGLTVASESMPGTRTATVGVWINAGSRADNPKSSGTAHFLEHLAFKGTQTRPQAALELEIENIGSQINAYTSRENTVYYTRCLASDIKQNIDILSDLLTKSKLENRAIDNERHVILQESDEVDKMYDEVVFDHLHAVAFKNQDLGRTILGPREMIKTINRQDLVDYITTNYKGDRMALVGVGCVDHQELVKLGKNFFGNIVKSEEPFNQSGGTLPLFYGDEIRIQDDSMPTTHVALAVEGVSWSAPDFFVASVANGIVGTWDRSVGIGSNSPSPLAVTAATGGPGKTPIANSYMAYTTSYADTGLLGVYFTADKNANLKLLVDAIQKEWGRLSRGDITDEEVERSKSQLKASLLLALDDSSAIAEDIGRQVVNTGYRLSPEEVFSRVESITKDDIVNWANYRLKGKPIALAAVGNVKTLPSHKEISEGMFF
Protein: Uridine phosphorylase 1 (C9J486)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGG
Protein: 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) (P0A6D3)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00210, ECO:0000305}.
Interaction partners:
- Shikimate kinase 2
- Chorismate synthase
- 3-dehydroquinate synthase
- Shikimate kinase 1
- Shikimate dehydrogenase
- T-protein
- Quinate/shikimate dehydrogenase
- Bifunctional chorismate mutase/prephenate dehydratase
- Cytidylate kinase
- Phosphoserine aminotransferase
Sequence:
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
Protein: FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Q91VS8)
Organism: Mus musculus (Mouse)
Function: Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
Interaction partners:
- Plexin-A1
- Cell division control protein 42 homolog
- Proto-oncogene tyrosine-protein kinase Src
- Ras-related protein Rap-1A
- Ras-related protein Rap-1b
- Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
- Neuropilin-1
- Plexin-A4
- Ras-related C3 botulinum toxin substrate 1
- Semaphorin-3A
Sequence:
MGEIEGTYRALPTSGTRLGGQTAIGVSTLEPEQSLSPRMQEKHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCTANTAALLISHLLQSEIGDYDETLDREHLKANEYLPNQEKSLEKILDFHQRHTGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLSDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYVKDGGMKRIPYERRHSKTRTSLHALTVDLPKQSVSFTDGLRTSASLSSANVSFYPPPSSSLSPPGLPNLKDSSSSLVDPQAPVIKSTAAERSSGPSSSDGPSTQSAHLPGPPVLRPGPGFSMDSPQPSPSSLKSHLSLCPELQAALSTAEQGASPVLSPVLSGAGTARMDNQEEQKHKHMPEDEAYFIAKEILATERTYLKDLEVITVWFRSVLIKEEAMPAALMALLFSNIDPVYEFHRGFLHEVEQRLALWEGPSSAHLKGDHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKHCKKLEAVYKEFELQKVCYLPLNTFLLKPVQRLVHYRLLLSRLCAHYSPGHRDYADCHEALKAITEVTTELQQSLTRLENLQKLTELQRDLVGVENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKSVTGASHFRIRGFLPLRGMLVEESENEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMQDLNAAIQAAKTIGDSPPVLLGGPVYTRTPRSSDEVSLEESEDGRGNRGSLEGNSQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSLPREADSIHKDYVFKLQFKSHVYFFRAESKYTFERWMDVIKRASSSPGRPPSFTQDCSHHSPGLEAEIREKEACPSPCLDKNL
Protein: Uncharacterized protein (Q57ZJ3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGENDNAQQLVDEINGNLIEWTTGGDSERLIFRLLDLYNRFMVAVHRDLVSCGDQGPALATAVCIPLWEMLHLYSGPLGPFRASSKAFAITLLTSLYPKTRDRRCLYQQLGCICSLGHPPVPLSWCLPMSTEVVEHVTGDGSAEDSYEAVVGYVRNTVSAEGNIIRASSSSVLNEKVGMLLEDVLPRCYLVVEESATACKEISYENAIIITIGANERSPSRSLCVLKPVIWKYLVLLHVYSPEDARSLGNYVTNSSWAQRTVRVSAQCEATYASLIGPIVHEAAVCTSLIGSNANAAPDNTPFLCPRLLGTLLPTGCRKGGLVDGYGNLTTPFKPNKIMRRGETVYQNVAASLHSALTESIPMELSFFNASSSCRDCDKLTLMCRSAMLTSVTQNSSIKGLPASVVGRMLFDRKRGRDDVYEGPMFLPSTSTLSDLLGEDEENKMYCTLERIAATHHPV
Protein: Protein TIFY 5B (Jasmonate ZIM domain-containing protein 7) (O64687)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Repressor of jasmonate responses.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein TIFY 11A
- Protein TIFY 9
- Protein TIFY 11B
- Protein TIFY 10A
- Protein TIFY 10B
- Protein TIFY 7
- Transcription factor MYC4
- Protein TIFY 6B
- Transcription factor MYC3
- Protein TIFY 3A
Sequence:
MIIIIKNCDKPLLNFKEMEMQTKCDLELRLLTSSYDSDFHSSLDESSSSEISQPKQESQILTIFYNGHMCVSSDLTHLEANAILSLASRDVEEKSLSLRSSDGSDPPTIPNNSTRFHYQKASMKRSLHSFLQKRSLRIQATSPYHRYR
Protein: Lysozyme (EC 3.2.1.17) (I1TEH9)
Organism: Salmonella phage SPN9CC
Interaction partners:
Sequence:
MAMSPALRNSVIAAISGGAIAIASVLITGPGGNDGLEGVRYKPYKDVVGVLTVCYGHVGKDIMLGKTYTEAECEALLNKDLATVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVCLWGQQ
Protein: LIM/homeobox protein Lhx9 (LIM homeobox protein 9) (Q9NQ69)
Organism: Homo sapiens (Human)
Function: Involved in gonadal development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- LIM domain-binding protein 1
- Single-stranded DNA-binding protein 3
- LIM/homeobox protein Lhx2
- POU domain, class 4, transcription factor 1
- Single-stranded DNA-binding protein 4
- Steroidogenic factor 1
- BarH-like 1 homeobox protein
- Wilms tumor protein
- Nuclear receptor subfamily 0 group B member 1
- LIM domain-binding protein 2
Sequence:
MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
Protein: Ropporin-1-like protein (Q66IC9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.
Subcellular location: Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9EQ00}. Cell projection, cilium {ECO:0000250|UniProtKB:Q96C74}.
Interaction partners:
- Ciliogenesis-associated TTC17-interacting protein
Sequence:
MPLSETMYCAQQINIPPALPNMLKQFTKAAIRTQPRDVLQWAADYFSALSKGQDLPVKKRLELPVATQKTDTGLTPGLLKILHQQLTSKETVTKDELLPKWKALHLPVEQLDTILALGNFSENINWMQFFALACSALGGSITSALKHACEILTEDPEGGPAQIPFHMFRSLYTYLAHLDGEIPEEQIDSFLHSLEGQAQSQGGMVQPSNFTSLHTAEK
Protein: Cbb3-type cytochrome c oxidase subunit (Q9I3G2)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004533, ECO:0000256|PIRNR:PIRNR000006}.
Interaction partners:
- Cytochrome c oxidase, cbb3-type, CcoO subunit
- cytochrome-c oxidase
- Cytochrome c oxidase, cbb3-type, CcoO subunit
- cytochrome-c oxidase
- Cytochrome c oxidase, cbb3-type, CcoQ subunit
- cytochrome-c oxidase
- cytochrome-c oxidase
- Probable ferredoxin
- Cbb3-type cytochrome c oxidase subunit
- Probable iron-sulfur protein
Sequence:
MTTFWSLYITALTVGTLIALLWLVFATRKGEAKGTTEKTMGHSYDGIEEYDNPLPKWWFMLYIGTIVFSVGYLVLYPGLGNWKGVLPGYEGGWTQDKQWEREMNIAQEKYGPIFAKYAAMPIEEVAKDEHAMKMGSRMFATYCSICHGSDAKGALGFPNLADNEWRWGGDPQSIETTILGGRHAIMAAWGDILGEDGVKNVAAYVRTELAGLKLPEGTKADVEAGKQIFSVNCVACHGPEGKGTALVGAPNLTNPGAFIYGSSYAQLQQTIRHGRQGQMPAQEPYLGKEKVHILAAYIYNLSHNQGSN
Protein: Protein phosphatase 1 regulatory subunit 13B (A0A3B3ISJ2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
EQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDHMMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA