wanglab/gogpt-training-data huggingface dataset:
Protein: Protein SDA1 (Severe depolymerization of actin protein 1) (P53313)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for 60S pre-ribosomal subunits export to the cytoplasm. May also be required for 60S ribosomal subunit maturation and accumulation. Involved in G1 events and passage through start, and possibly actin cytoskeleton organization.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:10704371, ECO:0000269|PubMed:12374754}.
Interaction partners:
- Ribosome biogenesis protein NOP53
- Nuclear GTP-binding protein NUG1
- Nucleolar GTP-binding protein 2
- Nucleolar GTP-binding protein 1
- Pre-rRNA-processing protein IPI3
- Ribosome assembly protein 4
- Pre-rRNA-processing protein RIX1
- Midasin
- Ribosome biogenesis protein NSA2
- Probable metalloprotease ARX1
Sequence:
MGRRSRAAMLPTNIILLQNLVKRDPESYQEEFLQQYAHYESLRDIFMLNGLAGGDSAAATNGLDVGNGSSTMAGTNGTTMSTSTSQLIELVGFVSQVCSCFPRETANFPSELKQLLLEHHKSLPFELKEKILSCLTMLRNKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLLKSCNTNGKNQKLNKSTQAVCFNLLDQPDSQGIWATKLTRELWRRGIWDDSRTVEIMTQAALHQDVKIVMSGVMFFLDADREREENFEENSEDEDGFDLDALRHKMQVNKKTGRRGKKLENAIKTVKKKKKNGPGAPQGYLNFSAIHLLRDPQGFAEKLFKEHLSGKTKNKFDMEQKISLMQLLSRLIGTHKLIVLGIYTFFLKYLTPKQRDVTRIMSACAQACHDLVPPEVINVMVRKIADEFVSDGVANEVAAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKKEHGEESENEDADANWEVDVDSEEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPIKYKQSREERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKGY
Protein: Transcription regulator (Q92L12)
Organism: Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Interaction partners:
Sequence:
MGATPIRKKYVVIDPTIRFLGHAQRGFRWRDTLVAFRSDPHRKRMESMMVEARNHGLFDGYIFPVHGRRGLMGNLTVGGRVVDLSPVELSLFDAIAKRLFWKLLELTDPEIMAELVSRVEVQMTRREMEALHYLADGMTSNDIGKVLDISSHTVDWYMNGIQEKLKAKNRHHVVAIAFRLGLIS
Protein: Uncharacterized mitochondrial membrane protein FMP10 (P40098)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- mRNA-binding protein PUF3
- 4-hydroxy-4-methyl-2-oxoglutarate aldolase
- Glutathione transferase 3
- Uncharacterized protein YGR161W-C
Sequence:
MFKRIAIAQIRTYTNGVVFKTASKPKRRWIPWTIFGGSFLGGWYLTQHMTFTDLLAYWRYDALPKNADEVVKYHADLNRRLNGLPIVKQLENAGFVQVIANEEENLLVSRALNTPGGVAIPPRVYYNPSRRETVGLYHLGMKLTGYPFLIHGGILATVIEDLMKEAIRLEKGTKNINQETKNLSISYKFPTLANQFVVVRTTDLQQYGNKTKLKAELMDQSGNRTLVKANATFSSEQGNPKEEK
Protein: Complement factor H-related 2 (A0A668KLU9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGFCSMLLLSNILLTAWLSTAKGEEKTCSPPYVPNIIYTPHRIIHRTADEIRYECKNGFYPATRSAVSKCTLTGWIPVPRCTLKPCEFPQFKYGRLYYEESLRPNFPVSIGNKYSYKCDNGFSPPSGYSWDYLRCTAQGWEPEVPCVRKCVFHYVENGDSTYWEKIYVQGQSLKVQCYNGYSLQNGQDTMTCTENGWSPPPKCIRINSTRTCGPPPPIDNGDITSLSLPEYEPLSSVDYQCQKYYLLKGNKTITCRNGNWSEPPMCLHACVIPENIMEAHNIILKWRHTEKIYAHSGEDIEFECKRGYQKARGSLPFRTKCINGTINYPTCV
Protein: Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcgammaRIIIa) (CD antigen CD16a) (A3RFZ7)
Organism: Macaca mulatta (Rhesus macaque)
Function: Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC). Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger. Mediates IgG effector functions on natural killer (NK) cells. Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation. Involved in the generation of memory-like adaptive NK cells capable to produce high amounts of IFNG and to efficiently eliminate virus-infected cells via ADCC. Regulates NK cell survival and proliferation, in particular by preventing NK cell progenitor apoptosis (By similarity). Fc-binding subunit that associates with CD247 and/or FCER1G adapters to form functional signaling complexes. Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation. The ITAM-dependent signaling coupled to receptor phosphorylation by PKC mediates robust intracellular calcium flux that leads to production of pro-inflammatory cytokines, whereas in the absence of receptor phosphorylation it mainly activates phosphatidylinositol 3-kinase signaling leading to cell degranulation (By similarity). Costimulates NK cells and trigger lysis of target cells independently of IgG binding (By similarity). Mediates the antitumor activities of therapeutic antibodies. Upon ligation on monocytes triggers TNFA-dependent ADCC of IgG-coated tumor cells (By similarity). Mediates enhanced ADCC in response to afucosylated IgGs.
Subcellular location: Cell membrane {ECO:0000269|PubMed:33208458}; Single-pass type I membrane protein {ECO:0000255}. Secreted {ECO:0000250|UniProtKB:P08637}. Note=Also exists as a soluble receptor. {ECO:0000250|UniProtKB:P08637}.
Interaction partners:
- T-cell surface glycoprotein CD3 zeta chain
- High affinity immunoglobulin gamma Fc receptor I
- Tyrosine-protein kinase
- High affinity immunoglobulin epsilon receptor subunit gamma
- Ig-like domain-containing protein
- CD19 molecule
- Low affinity immunoglobulin gamma Fc region receptor III-A
- Tyrosine-protein kinase
- Tyrosine-protein kinase
- T-cell surface glycoprotein CD4
Sequence:
MWQLLLPTALLLLVSAGMRAEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTRWFHNESLISSQTSSYFIAAARVNNSGEYRCQTSLSTLSDPVQLEVHIGWLLLQAPRWVFKEEESIHLRCHSWKNTLLHKVTYLQNGKGRKYFHQNSDFYIPKATLKDSGSYFCRGLIGSKNVSSETVNITITQDLAVSSISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKKSVPSSTRDWEDHKFKWSKDPQDK
Protein: Large ribosomal subunit protein bL9c (50S ribosomal protein L9, chloroplastic) (CL9) (P25864)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to the 23S rRNA.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL4c
- Large ribosomal subunit protein uL15c
- Large ribosomal subunit protein bL27c
- Large ribosomal subunit protein bL28c
- Large ribosomal subunit protein uL24c
- Small ribosomal subunit protein uS9c
- Large ribosomal subunit protein bL17c
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain-containing protein
- 50S ribosomal protein L33
Sequence:
MASSTALSLSWSSSPCWSHSFNGGANETLKVSERRFNFEVVSQKKAKKLRKVILKEDVTDLGKQGQLLDVKAGFFRNFLLPTGKAQLMTPLLLKELKMEDERIEAEKQRVKEEAQQLAMVFQTVGAFKVKRKGGKGKLIFGSVTAQDLVDIIKSQLQKDIDKRLVSLPEIRETGEYIAELKLHPDVTARVKINVFAN
Protein: Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1) (P51522)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein SSXT
- Protein SSX1
Sequence:
MHGRKDDAQKQPVKNQLGLNPQSHLPELQLFQAEGKIYKYDHMEKSVNSSSLVSPPQRISSTVKTHISHTYECNFVDSLFTQKEKANIGTEHYKCSERGKAFHQGLHFTIHQIIHTKETQFKCDICGKIFNKKSNLASHQRIHTGEKPYKCNECGKVFHNMSHLAQHRRIHTGEKPYKCNECGKVFNQISHLAQHQRIHTGEKPYKCNECGKVFHQISHLAQHRTIHTGEKPYECNKCGKVFSRNSYLVQHLIIHTGEKPYRCNVCGKVFHHISHLAQHQRIHTGEKPYKCNECGKVFSHKSSLVNHWRIHTGEKPYKCNECGKVFSHKSSLVNHWRIHTGEKPYKCNECGKVFSRNSYLAQHLIIHAGEKPYKCDECDKAFSQNSHLVQHHRIHTGEKPYKCDECGKVFSQNSYLAYHWRIHTGEKAYKCNECGKVFGLNSSLAHHRKIHTGEKPFKCNECGKAFSMRSSLTNHHAIHTGEKHFKCNECGKLFRDNSYLVRHQRFHAGKKSNTCN
Protein: Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1) (Q80Z96)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000269|PubMed:23029439}; Multi-pass membrane protein {ECO:0000269|PubMed:23029439}.
Interaction partners:
- Prickle-like protein 2
- Prickle-like protein 1
- Segment polarity protein dishevelled homolog DVL-1
- Segment polarity protein dishevelled homolog DVL-2
- Prickle planar cell polarity protein 3
- Predicted gene 21981
- Segment polarity protein dishevelled homolog DVL-3
- Vang-like protein 2
- Cadherin EGF LAG seven-pass G-type receptor 1
- Frizzled-6
Sequence:
MDTESTYSGYSYYSSHSKKSHRQGERTRERHKSPRNKDGRGSEKSVTIQAPAGEPLLANDSARTGAEEVQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPQILWREELKPCGAICEGLLISVSFKLLILLIGTWALFFRKQRADVPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDQNYKDIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRRARLVVAVEEAFIHIQRLQAEEQQKSPGEVMDPREAAQAIFPSMARALQKYLRTTRQQHYHSMESILQHLAFCITNSMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLISEEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIVLSEEFIDPKSHKFVLRLQSETSV
Protein: NAD-dependent glycerol dehydrogenase (EC 1.1.1.6) (Dha-forming NAD-dependent glycerol dehydrogenase) (Q92EU6)
Organism: Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Function: Involved in the glycerol metabolism. Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). GolD specifically uses NAD.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:22773791}.
Interaction partners:
- PEP-dependent dihydroxyacetone kinase 2, ADP-binding subunit DhaL
- PTS-dependent dihydroxyacetone kinase 2, dihydroxyacetone-binding subunit DhaK
- PEP-dependent dihydroxyacetone kinase 2, phosphoryl donor subunit DhaM
- Triosephosphate isomerase 2
- Ribose-5-P isomerase B
- Glycerol kinase
- PEP-dependent dihydroxyacetone kinase 1, ADP-binding subunit DhaL
- PTS-dependent dihydroxyacetone kinase 1, dihydroxyacetone-binding subunit DhaK
- PEP-dependent dihydroxyacetone kinase 1, phosphoryl donor subunit DhaM
- Transketolase
Sequence:
MTFKGFDKDFNITDKVAVVTGAASGIGKAMAELFSEKGAYVVLLDIKEDVKDVAAQINPSRTLALQVDITKKENIEKVVAEIKKVYPKIDILANSAGVALLEKAEDLPEEYWDKTMELNLKGSFLMAQIIGREMIATGGGKIVNMASQASVIALDKHVAYCASKAAIVSMTQVLAMEWAPYNINVNAISPTVILTELGKKAWAGQVGEDMKKLIPAGRFGYPEEVAACALFLVSDAASLITGENLIIDGGYTIK
Protein: Nuclear pore protein (Q38AQ7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus envelope {ECO:0000256|ARBA:ARBA00004259}. Nucleus, nuclear pore complex {ECO:0000256|RuleBase:RU364035}.
Interaction partners:
- Nucleoporin
- Nucleoporin
- Nucleoporin NSP1-like C-terminal domain-containing protein
- Nuclear pore complex protein
- Uncharacterized protein
- Long-chain-fatty-acid-coA ligase protein,putative
- Protein transport protein Sec13, putative
- Nucleoporin
- Poly
- Telomerase-associated protein, putative
Sequence:
MMSIPNLTDAPGGILIAHSHNQSTSAVPSGGSVDPNNDVRGNITRLTARARQLLVSDIDTRVVRNGLSTYEMSRKTATDARLWAQVAGQATSSQASVELFMASLGFNLQEQLRLLHQLHTNQLPIVGRNQLDSLDAPWDTQASDELGTALEVFVANRRHEIMQRSVDEMHQRVGEMMQERSEAIIRSSWEKYSVEIADVFETASLKAGSGGGRGGNSRNSISNGQLMHASTLGGAVNGVAAAGTALQSHAGVVALLNGRDTASTKALAKVSAFAHIVHTQPPQKWSSHFTNHVVDDTPNSVEEVAVLWTTVGHILQPIIERGSAATSITYVSSSRRVMERKALAAVFSIMLKVESDRLSDMENMHATRFIGVVERYTSSSNPWAHIFTSMRCGRYDAAAAIAAAAGFGLVEKTLSSYASGNVMEQYTPSCPLELRALYSEDCTRSDPYRHTVLFLLLAGKTGESNEVVQSTVASLSSKVARSLEDTLWIRLFCLHTVDANNSEKIQSLSDMQRLLLDDMQDLVALTRGNVVRLASLMFHALLPSSGVRLLTENDSTYVDGVHLAMCFHNSKMLQCSDAEVPLDLSRAIQQYCSIALLDADRRRMNASQVGPAIFWYFFRTGLIDTFVDYCSNELVCAKLFGQRAGGGSNDGALFQHGGVPPNELLDAMVRIAEDAIARGKTELAVHVLTVLDHAATLVSDDARSGYALSRAVQKICPALAQAFHNEPTSESANLFVHAAVLRERLAQTKCVIPSAQTDTFHLLCRMGEVHANAVRGNAEMAVRCFCNLPFVPASPADVERCAELFDTAPDTVATAAPPIIIHALRQLLRLVKEQRALHDGASDELLLQRNQAQQIIAWVRRWKRHMNRSLLDELIVLERLFVQ
Protein: 60S ribosome subunit biogenesis protein NIP7 (Nuclear import protein 7) (Q08962)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
Subcellular location: Cytoplasm. Nucleus, nucleolus.
Interaction partners:
- Ribosome biogenesis protein NSA2
- Nucleolar complex-associated protein 3
- Ribosome biogenesis protein ERB1
- Ribosome assembly factor MRT4
- Nuclear GTP-binding protein NUG1
- Ribosomal RNA-processing protein 1
- Ribosome production factor 1
- 27S pre-rRNA
- Nucleolar GTP-binding protein 1
- Ribosome biogenesis protein RLP24
Sequence:
MRQLTEEETKVVFEKLAGYIGRNISFLVDNKELPHVFRLQKDRVYYVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEMPFLYGNHVLKAHVGKMSDDIPEHAGVIVFAMNDVPLGFGVSAKSTSESRNMQPTGIVAFRQADIGEYLRDEDTLFT
Protein: Serine/threonine-protein kinase WARTS homolog (EC 2.7.11.1) (LATS kinase homolog) (O45797)
Organism: Caenorhabditis elegans
Function: Phosphorylates yap-1 which may negatively regulate yap-1 nuclear localization. Plays an essential role in larval development. Regulates growth, the formation of gut granules, lifespan and cell and body sizes probably in synergy with the TGF-beta sma/mab pathway. Does not appear to regulate apoptosis and proliferation. In addition, may synergize with the TGF-beta daf-7 dauer pathway to regulate entry into the dauer stage. Maintains the cellular integrity of intestinal cells by regulating the localization of apical actin and junctional proteins.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:19605499, ECO:0000269|PubMed:19737560}. Apical cell membrane {ECO:0000269|PubMed:19605499, ECO:0000269|PubMed:19737560}. Note=In epithelial cells, localized near the plasma membrane. In intestinal cells, localized in the subapical membrane region (PubMed:19605499, PubMed:19737560). Membrane localization starts in the late embryo (PubMed:19605499). {ECO:0000269|PubMed:19605499, ECO:0000269|PubMed:19737560}.
Interaction partners:
- Yes-associated protein homolog 1
- Mob1/phocein
- Serine/threonine-protein kinase cst-1
- Serine/threonine-protein kinase cst-1
- Mps one binder kinase activator-like 2
- Protein salvador homolog 1
- MOB kinase activator-like 3
- TBC domain-containing protein kinase-like protein
- Transcription enhancer factor-like protein egl-44
- FERM domain-containing protein
Sequence:
MRPAAPGTTPNGASSDIRHQRGVAPIPFGSTNSAIDAHHNSEIRVGRHRAKLDEIRESLKAYEHEAGLLSSHVALGSLATPSSSSVSHSDITNDNAEVMNFSSSSSNAAATTTTVSSAAVSNSNSFRTEGGGHKMRITPMPQRHLMMDTGANETVFRSGKEMIRNGNPSTTISSTPSTTTEESIRIHPAGYRYDMPTPAYHMNNNAPQYSPGYSRPPPPAYDSSPVNTRMTPVATDNYRTHLHMKVHPVVKAPPPNPTMLNHNKNMAPPPPPPAKSTISIETMSEERKADNIQRLYHTSMDKKTASSVVSINVASPHTTKVNVGDSPLPSKSFIIGPRYTADVDRKNFVNYKDELRPDPRLIPSTSDANHEDFRPILFKPRNLEITMKSRAQPPPPQYNQPSEPPPKRVSSPIDRTLLEPYIKNTRRVQPCKPNMLRFYMEQHVERLLQQYKEREKRMKQLEKEMVSAQLPDIMRNKMLGLLQQKESKYTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLICDASSRLGSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHDEDTSNFETFQDNDRADKPNVRGLHNPAFYEFTYRHFFDTDSVGCPSLRPSRRRSLRPLLENGTFNESVSEEDSSSHI
Protein: RE56731p (Serrano, isoform A) (Serrano, isoform B) (Serrano, isoform C) (Serrano, isoform D) (Serrano, isoform E) (Q6NLM8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAATDGQIILAASRFGDATPVYLRDFSKQPLPAVAKIIKGQHQALGVPTLSAPSLQSTALFLSAGKKYQILAQPIKIKEGRKPTNVGAKVLIPETYGGYFELLSEDGRSTRCIDSVLELSRRRNARVLVRETFRCQQMNRTIHAGELLTTMNDNGKYLQCRNIKDEIINLPLDTKAKFSPIAREDSISGVHTVKNLLLKRMPVIVRLVHGSAPKGLKQPFVPELRLLGCVEIDRIFALPLQKDTDLVPVPLNAKIKLQRAKNMEQLEHFIEYSRFLDKAQRLLADARDRLQIVDLKLSEKEKKDSKFNSRNGGRLPVVMLPSAAGMASGLAESGYVLRKSASCDSWSKQQQQALSSSEIAEEYNEIDHIYDYVRGLTPLSKGLARFEPICESPTLRSHHTDSGSGNYCSLIRAPVHQQATTSGNNNYSSLESNKHSSSGGGHHPGSHHHHHHHVVNHYHHGHIQEDIKPVPPPIETIPGKKPAEKRQRPTLPKLYIKNAHSAGSSSNGNSTGTTHSTSHSHSHSHSHVHSHSHGQSQSQQQPPTPNGNTGNAVANAAASAVAAAHHGSHGSHGSHLHPHPHASVHPHPHPHHGKVLTPNNHLPSKEALEPQSPLFHIRYKSLSSLQLTPDNNNCSSVTPPTISAHGKSSGAGVGSGATASGTPGTPGTPPDVGLKCGSILNVHGYLSSPHPLPLPLPHSRSSSSNNHHNPREGTLDSSRSGGRTSGDSNKLPEKKTRRLSRPRSLSNLVWDLRPSKEKSKKKLYIHHFDQRQQATLYL
Protein: Mesoderm posterior protein 1 (Class C basic helix-loop-helix protein 5) (bHLHc5) (Q9BRJ9)
Organism: Homo sapiens (Human)
Function: Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription factor SOX-17
- Homeobox protein Nkx-2.5
- Transcription factor GATA-4
- Myocyte-specific enhancer factor 2C
- Heart- and neural crest derivatives-expressed protein 2
Sequence:
MAQPLCPPLSESWMLSAAWGPTRRPPPSDKDCGRSLVSSPDSWGSTPADSPVASPARPGTLRDPRAPSVGRRGARSSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPSVAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEESLQRRCRQRGDAGSPRGCPLCPDDCPAQMQTRTQAEGQGQGRGLGLVSAVRAGASWGSPPACPGARAAPEPRDPPALFAEAACPEGQAMEPSPPSPLLPGDVLALLETWMPLSPLEWLPEEPK
Protein: Hairy/enhancer-of-split related with YRPW motif protein 2 (Protein gridlock) (Q9I9L0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Neurogenic locus notch homolog protein 1
- Delta-like protein
- Hairy/enhancer-of-split related with YRPW motif protein 1
- Hairy/enhancer-of-split related with YRPW motif-like protein
- Protein jagged-1a
- COUP transcription factor 2
- Delta-like protein
- Ephrin type-B receptor 4a
- Ephrin-B2a
- Recombination signal-binding protein for immunoglobulin kappa J region a.
Sequence:
MKRPCEDSTSDSDMDETIDVGSENNYSGQSNGSFIRCGSPTTTSQVMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHSLAMDFLSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSSCASQREAAAMTTSIAHHQQALHPHHWAAALHPIPAAFLQQSGLPSSESSSGRLSEAPQRGAALFSHSDSALRAPSTGSVAPCVPPLSTSLLSLSATVHAAAAAAAAQTFPLSFPAGFPLFSPSVTASSVASSTVSSSVSTSTTSQQSSGSSSKPYRPWGTEVGAF
Protein: Lysophosphatidic acid receptor 6a (Zgc:153784) (Q08BG4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- C-C motif chemokine
- Tripartite motif-containing 35-23
- Tripartite motif-containing 35-25.
Sequence:
MYNTSLEMEMLNVSNVTHCPKNDNFKYPLYSMVFSIVFMVGLITNVAAMYIFMCSLKLRNETTTYMMNLVVSDLLFVLTLPLRVFYFVQQNWPFGSLLCKLSVSLFYTNMYGSILFLTCISVDRFLAIVYPFRSRGLRTKRNAKIVCAAVWVLVLSGSLPTGFMLNSTNKLENNSISCFENFSSKEWKSHLSKVVIFIETVGFLIPLMLNVVCSAMVLQTLRRPNTVSRGGKLNKKKILRMIIVHLFIFCFCFIPYNVNLVFYSLVRTNTLKGCAAESVVRTIYPIALCIAVSNCCFDPIVYYFTSETIQNSIKRKTQTGHSIDVKFSEALQSETSSTLQFSLRSIKNKMFHNESHV
Protein: Nucleoside diphosphate kinase, cytosolic (NDK) (NDP kinase) (EC 2.7.4.6) (P22887)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Major role in the synthesis of nucleoside triphosphates other than ATP.
Subcellular location: Cytoplasm.
Interaction partners:
- CTP synthase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
- Thymidylate kinase
- Inosine triphosphate pyrophosphatase
- Ribonucleoside-diphosphate reductase large subunit
- Guanosine-3',5'-bis
- UMP-CMP kinase
- Guanylate kinase
- dCTP deaminase
- dCTP deaminase
Sequence:
MSTNKVNKERTFLAVKPDGVARGLVGEIIARYEKKGFVLVGLKQLVPTKDLAESHYAEHKERPFFGGLVSFITSGPVVAMVFEGKGVVASARLMIGVTNPLASAPGSIRGDFGVDVGRNIIHGSDSVESANREIALWFKPEELLTEVKPNPNLYE
Protein: Stromal cell-derived factor 2-like protein 1 (SDF2-like protein 1) (Q9ESP1)
Organism: Mus musculus (Mouse)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
Interaction partners:
- DnaJ homolog subfamily B member 11
- Endoplasmin
- Protein disulfide-isomerase A4
- Hypoxia up-regulated protein 1
- Protein disulfide isomerase Creld2
- Sorting nexin-5
- Endoplasmic reticulum chaperone BiP
- Protein disulfide-isomerase A6
- Peptidyl-prolyl cis-trans isomerase B
- Protein disulfide-isomerase
Sequence:
MWGASRGRVAGPTLLGLLLALSVRSGGASKASAGLVTCGSVLKLLNTHHKVRLHSHDIKYGSGSGQQSVTGVEESDDANSYWRIRGGSEGGCPRGLPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREASVRFQHVGTSVFLSVTGEQYGNPIRGQHEVHGMPSANAHNTWKAMEGIFIKPGADLSTGHDEL
Protein: Probable glycine cleavage system H protein 1, mitochondrial (Q54JV8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity).
Subcellular location: Mitochondrion {ECO:0000305}.
Interaction partners:
- Aminomethyltransferase, mitochondrial
- Glycine dehydrogenase
- Serine hydroxymethyltransferase 2
- Serine hydroxymethyltransferase 1
- Dihydrolipoyl dehydrogenase, mitochondrial
- Serine--pyruvate aminotransferase
- Putative glycine cleavage system H protein 3
- Glycine cleavage system H-like protein gcvH2
- BPL/LPL catalytic domain-containing protein
- Type-3 glutamine synthetase
Sequence:
MLKTLRFGTRAFGQNLNIAKRNFCTRYTNDHEWVTSLGSQNYRLGITDFAQKQLGDIVFVEIPQIGATLSQGQPITVVESVKAASDIYIPMDGSITTVNQELESSPELVNEEPMGDGWIVEYKSSKTDQFQSLMNKAQYDEYIKEH
Protein: Large ribosomal subunit protein eL34x (60S ribosomal protein L34-3) (Q9LJW6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL24y
- Large ribosomal subunit protein uL24z
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL22y
- Large ribosomal subunit protein eL32z
- Large ribosomal subunit protein eL8z
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL8y
- Large ribosomal subunit protein uL4y
- Large ribosomal subunit protein uL4z
Sequence:
MVQRLVYRSRHSYATKSNQHRIVKTPGGKLTYQTTNKRASGPKCPVTGKRIQGIPHLRPAEYKRSRLARNERTVNRAYGGVLSGVAVRERIVRAFLVEEQKIVKKVLKLQKAKEKTAPKS