wanglab/gogpt-training-data huggingface dataset:
Protein: E3 ubiquitin-protein ligase hrd-1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase hrd-1) (Suppressor/enhancer of lin-12) (Q20798)
Organism: Caenorhabditis elegans
Function: Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated ubc-7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system, which is also called the ER-associated degradation (ERAD) system, involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins. Protects cells from ER stress-induced apoptosis. Thought to play a role together with hsp-3 in developmental growth and function of intestinal cells and to play a role together with hsp-4 in gonad formation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- S5 DRBM domain-containing protein
- Derlin-1
- Derlin-2
- Transitional endoplasmic reticulum ATPase homolog 2
- RING-type E3 ubiquitin transferase
- Ubiquitin-conjugating enzyme E2 G2
- Transitional endoplasmic reticulum ATPase homolog 1
- Endoplasmic reticulum lectin 1
- MRH domain-containing protein
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
Sequence:
MRVSAGLMIGGSCVATAATILNAFLINKQFYPSIVYLSKSNASMAVIYVQGIVLVYLMFQLLKSILFGDLRAAEAEHLSERTWHAVLETCLAFTVFRDDFSAIFVMQFIGLLFIKCFHWLADDRVDMMERSPVITLRFHLRMMTVLAALGFADSYFVSSAYFTTITRGASAQIVFGFEYAILLALVLHVTIKYLLHMHDLRNPQSWDNKAVYLLYAELFINLIRCLLYGFFAVVMLRVHTFPLFSVRPFYQSVRALHKAFLDVILSRRAINAMNSQFPVVSAEDLAAMDATCIICREEMTVDASPKRLPCSHVFHAHCLRSWFQRQQTCPTCRTDIWQGRNGAAAGGNAADAAANVADANVAGAQIGAGMPPFLPFLGHQFGFPQQPAGAGGAQPGAAQAGGQPGPFPHQIFYAPAPANRPEFMNLIPPPPLPMAGPPGMFPMMPPPPLPQVNTTQGTSSETPPVNPSYSQLSTEELRRMEGESREALLARLQAMDNIMVLLESAQMQMIQLATVTPIRPRPVVPSDESEQEAPGPSTDQVTSEEQEIPATSSAPSIFRTESPSTSSTAPSTSSPVTASSTPTTSSTRTPEAEEVRQRRLARLLGENANQ
Protein: Stevor (Q9U5L9)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKMYYLKMLLFTFLINTLILPHYENYLNNDYNVSFIQNNTKRTTIKSRLLAQTQIHNPHYHNDPELKEIIDKMNEEAIKKYQQTHDPYEQLKEVVEKNGTKYSGGNDAEPISTLEKELLETYEEIFGNESDMLKSGMSPNVDEKSSTFECTDINGVKLAKTKGRDKYLKHLKGRCTRGIYFCSLGSVILTYIGTTAAKGAAISTAGAGSKNCIYAISIFHMLNHKSMSSALTALGTVGCAADYASGATSASAIFLPCGIAALVLLILTVLLIILYIWLYRRRKRSWKHECKKHLCK
Protein: Small ribosomal subunit protein eS25 (40S ribosomal protein S25) (P62853)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62851}.
Interaction partners:
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein eS24
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein eS12
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS14
Sequence:
MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA
Protein: Potassium channel toxin alpha-KTx 9.7 (BjTx-2) (P83406)
Organism: Hottentotta judaicus (Black scorpion) (Buthotus judaicus)
Function: Calcium channel activator. Rapidly and reversibly activates ryanodine receptor 1 (RYR1).
Subcellular location: Secreted {ECO:0000269|PubMed:15067003}.
Interaction partners:
Sequence:
VGCEECPAHCKGKNAIPTCDDGVCNCNV
Protein: Ras guanine nucleotide exchange factor F (RasGEF domain-containing protein F) (Q54C94)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Promotes the exchange of Ras-bound GDP by GTP.
Interaction partners:
- Dyp-type peroxidase family protein
Sequence:
MTDKLKFKTSLLNKVPPPPPKSNQPSPSTSTPASPNVNSTNNSPSVSPATTSPIPSPGMSPLLTPENNNNNTNIPHQTSLLNNSISNKSSVSFLNNSGGNTINKSSPLSQSSSNIKNGGPIRTSTTLAQFSGSSLPNTENSSPPPSSSLISSSSSPTAESLLYSEDSIASGGTVTVDPNTKNGNIYNGNGLRNNSADILPHNNHTYCVGDDGFYLFGGTLPDGSYTNDFYTFQFAIKAWTILTFGSAPSIRTRHTGVLYNNSMYIFGGYSPSGPKNDIYVFSFDTQTWSEVQTEGTKPSPRYGHTAVVESGHMIVFGGISCDQTTKQQTVNNDIFSLNLDTKQWSQVLSTCPPSPRTHHTATMHKGNMYVFGGQDQQSNQVEDIVHCYTWASNSWKSIQFEGSSMTPRSDHSAVLFQDSIFISGGSSKSQTSQNLEIYEYDLYQKKCFKISSSTIVQNRISHSSVVKGNSILFWGGCTDNSFDYFSFGKDEFEEDYQDDYESNRVQNIPKELWEASLMKKHPEILELREKTLAFTGSKSFAKTLATPSFSENRLALSHQFVLQLIMEYLERNTYHKVIAAIQKESGVLHQPTESGESRLVSLLRLVKPRLRNKNVFDTDLSLFSKEEGNDPEVAVVDHLYHDYRHFDEEEDINVWEEGEDNNRNIRKVETDNNKVQIKAATFNKLIHYLAPKEKAFDPNFLKVFLYTHSSFTTSEKLLKKLIQRYQVPNSNANEPKYKSEVVEPVRQRVVDVLKYWVDKCPWDFNAGPTSSVLVATLNNFIDGSLTRDGNSNIKKLRELKKKLQHEDVRPYSEPPPEPKVPKNIFSPQLTLAHIDELEIARQMTLVESKLFGAIPPPEFMVRVIGYGEFQYNMATSPNLMTFVNRATDVSRWIVHTVLNESRDKKNKMKMLDKFIKTTECLRQLNNFQTLHSVLQGLQHPLLLSRPDLFTPRHREIIADHEMLFSKIDNYKLYREALARSQPACVPWIDIIREDFAQIERDQPSNMNNLINFTKRQNLYEILSKIGHYQFPYNLQIVHQVATFVNKLPKYSEYDLNLLSESLQSQVNSPLAGVYQPSLIGTTGSSSSINLGSARELNNSNRDSNNITGSSSNNNSNSSNSLSPIVKL
Protein: Transmembrane protein 143 (Q8VD26)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- IQ domain-containing protein E
Sequence:
MTVARWLRLWERGQAMLHVTWGSKVRLWSLVPALLGTPRALSSLENRMGVYRKMWNPKEPCDWAQQYRERFIPFSKEQLLRLLIQEFHSSPAERAALEAFSAHVDFCTLFHYHQLLARLQALYDPINPDRETLDQPSLTDPERLSSEKDVLQALRPLLAQANFSPLSEDALAYALVVHHPQDEVQVTINLDQYIYIQFWALGQRVGQMPHKSSVGSKRGFFRKLPPVERRYFKRVVLAARTKGGHLVLKSFKDTPLEGLEQLLPELKVRTPVLQRALLNLMLVVSGVMIFVNVGMVILSDLKMATSLLLLLFAAFMGVKASKVFGQRRSAQALELAHVLYYRSTSNNSELLSALALRAQEEHIKEALLAHSFLARRPGGSQGKPEETSRWLQSEVESWLLAQSGCDVTFNGPRALAHLQALTPSLGLFPLPELPQLDPMVLGTPEATQAALGSSYPSP
Protein: Non-structural maintenance of chromosome element 6 (Non-SMC element 6) (Core protein 1) (O13688)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. May prevent formation of excessive Holliday junctions or assist in their resolution.
Subcellular location: Nucleus {ECO:0000269|PubMed:16478984, ECO:0000269|PubMed:16823372}. Chromosome {ECO:0000269|PubMed:16478984}.
Interaction partners:
- Non-structural maintenance of chromosome element 5
- Structural maintenance of chromosomes protein 5
- Structural maintenance of chromosomes protein 6
- Non-structural maintenance of chromosome element 4
- Non-structural maintenance of chromosome element 3
- Non-structural maintenance of chromosomes element 1
- E3 SUMO-protein ligase nse2
- BRCT-containing protein 1
Sequence:
MNASNNISKFPDLDNSSKLIDHILDSDDSEELDELPDISSLVPSARAQSRKQYLKNDSSNSSTYRWNIDLLSSTATIDDSVAKRRKLAVQNLLQYDSTQTFQTGDEIDELIGKSVGSNVLNVLRSNPIYDDDLRYEYCSNSKARVPDWNTLKAECLKDNDLEFNEGIIPTTFGDLLSAKLVPLDIALSICSLQFFRSLGDTTCSEWIANLEKIFYSYKSSSNNLNQIVRFIFETTADMIGIDLAKRQVPIQLERTSASENLKSNLKIKVINFLKCCGTLYRFSDDTVRFEMIQDACRILIDNQVGSFCKWQFSQFMELPISLNPDFLISNIHKVSESPRVWVTILSSLSRSCQKFRKKIAFTLFVGKQSKNDDSDFSSLCQRLDEISASCNNDYTTLLYQIRTFGYAVDEKHFKTNERLECLLEKLRKIDLTISGSTDHLLLSRCEVKDCIHRLFMVLYYLNTNSAPELERIIESDLPNNNKQKDRYFKDKTSNLSMKENKSFSAKKVKKGKKKNKRQAYKR
Protein: Methylenetetrahydrofolate dehydrogenase [NAD(+)] (EC 1.5.1.15) (Q02046)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Serine hydroxymethyltransferase, cytosolic
- Aminomethyltransferase, mitochondrial
- Phosphoribosylglycinamide formyltransferase
- Serine hydroxymethyltransferase, mitochondrial
- Thymidylate synthase
- 5-formyltetrahydrofolate cyclo-ligase
- C-1-tetrahydrofolate synthase, cytoplasmic
- C-1-tetrahydrofolate synthase, mitochondrial
- Methylenetetrahydrofolate reductase 2
- Methylenetetrahydrofolate reductase 1
Sequence:
MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRNVELSKEK
Protein: Pre-mRNA-splicing factor CWC22 (Complexed with CEF1 protein 22) (P53333)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in pre-mRNA splicing.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pre-mRNA-splicing factor SNU114
- Pre-mRNA-processing protein 45
- Pre-mRNA-splicing factor SLU7
- Pre-mRNA-splicing factor SYF1
- Peptidyl-prolyl isomerase CWC27
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor CWC21
- Splicing factor YJU2
- Pre-mRNA-splicing factor BUD31
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22
Sequence:
MSTATIQDEDIKFQRENWEMIRSHVSPIISNLTMDNLQESHRDLFQVNILIGRNIICKNVVDFTLNKQNGRLIPALSALIALLNSDIPDIGETLAKELMLMFVQQFNRKDYVSCGNILQCLSILFLYDVIHEIVILQILLLLLEKNSLRLVIAVMKICGWKLALVSKKTHDMIWEKLRYILQTQELSSTLRESLETLFEIRQKDYKSGSQGLFILDPTSYTVHTHSYIVSDEDEANKELGNFEKCENFNELTMAFDTLRQKLLINNTSDTNEGSNSQLQIYDMTSTNDVEFKKKIYLVLKSSLSGDEAAHKLLKLKIANNLKKSVVDIIIKSSLQESTFSKFYSILSERMITFHRSWQTAYNETFEQNYTQDIEDYETDQLRILGKFWGHLISYEFLPMDCLKIIKLTEEESCPQGRIFIKFLFQELVNELGLDELQLRLNSSKLDGMFPLEGDAEHIRYSINFFTAIGLGLLTEDMRSRLTIIQEVEDAEEEEKKLREEEELEKLRKKARESQPTQGPKIHESRLFLQKDTRENSRSRSPFTVETRKRARSRTPPRGSRNHRNRSRTPPARRQRHR
Protein: Actin, alpha 2, smooth muscle, aorta (F1P476)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
Protein: Metalloendoproteinase 4-MMP (At4-MMP) (EC 3.4.24.-) (Matrix metalloproteinase 1) (AtMMP1) (Q8GWW6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Matrix metalloproteinases (MMPs) or matrixins may play a role in the degradation and remodeling of the extracellular matrix (ECM) during development or in response to stresses (By similarity). Active on myelin basic protein (MBP) and, to some extent, on McaPLGLDpaAR-NH(2) (QF24) and beta-casein.
Subcellular location: Cell membrane {ECO:0000255}; Lipid-anchor, GPI-anchor {ECO:0000255}; Extracellular side {ECO:0000305}.
Interaction partners:
- Plasminogen activator inhibitor
- FCS-Like Zinc finger 3
- RHOMBOID-like protein 2
- FCS-Like Zinc finger 2
- Protein IQ-DOMAIN 22
Sequence:
MHHHHHPCNRKPFTTIFSFFLLYLNLHNQQIIEARNPSQFTTNPSPDVSIPEIKRHLQQYGYLPQNKESDDVSFEQALVRYQKNLGLPITGKPDSDTLSQILLPRCGFPDDVEPKTAPFHTGKKYVYFPGRPRWTRDVPLKLTYAFSQENLTPYLAPTDIRRVFRRAFGKWASVIPVSFIETEDYVIADIKIGFFNGDHGDGEPFDGVLGVLAHTFSPENGRLHLDKAETWAVDFDEEKSSVAVDLESVAVHEIGHVLGLGHSSVKDAAMYPTLKPRSKKVNLNMDDVVGVQSLYGTNPNFTLNSLLASETSTNLADGSRIRSQGMIYSTLSTVIALCFLNW
Protein: eIF4G1 variant protein (Q4LE58)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
APLFPNRCWGDPDVAPNEMNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Protein: Uncharacterized protein YLR271W (Q06152)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Pre-mRNA-splicing factor SPP2
- Protein PXR1
- Pre-mRNA-splicing factor SPP382
- Protein SQS1
- Pre-mRNA-splicing factor NTR2
Sequence:
MEESKTKRKEDRIDLKNTPPQKKSKRDSTNDETARTSLRSIMPRGYKMMENMGYKEGETLGSNESALKEPIKVEINTKRRGIRAEKPDPSTMNDMQMSEQRFIKRESEMKNNKRLKKIWYRIQKVAFEMMGDSDLYNPGEDPRDFNVLWRSYVMQLNEEVAKNDLNNHSNNDNEDKNNMIPMVNESLEASPAIKGEKFGRPSTLIDCDTSIIGSRITKDTELAELEELSIEKRITKLNIFLRSEKYYCFFCGIKYKDEGDLYEHCPGVNEDDHK
Protein: Semaphorin-6A (Semaphorin Q) (Sema Q) (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1) (O35464)
Organism: Mus musculus (Mouse)
Function: Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:20881961}; Single-pass type I membrane protein {ECO:0000269|PubMed:20881961}.
Interaction partners:
- Plexin-A2
- Plexin-A4
- Neuropilin-1
- Plexin-A1
- Plexin-A3
- Neuropilin-2
- Plexin-D1
- Hepatocyte growth factor
- Plexin-C1
Sequence:
MRPAALLLCLTLLHCAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMNRTLYVAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLKKNDDTLFVCGTNAFNPSCRNYRVDTLETFGDEFSGMARCPYDAKHANIALFADGKLYSATVTDFLAIDAVIYRSLGDSPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIANVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLEKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNAAGPYQNHTVVFLGSEKGIILKFLARIGSSGFLNGSLFLEEMNVYNPEKCSYDGVEDKRIMGMQLDRASGSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWVRESGSCAHLSPLSRLTFEQDIERGNTDGLGDCHNSFVALNGHASSLYPSTTTSDSASRDGYESRGGMLDWNDLLEAPGSTDPLGAVSSHNHQDKKGVIRESYLKSNDQLVPVTLLAIAVILAFVMGAVFSGIIVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPEAILTPLMHNGKLATPSNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPNRGSREWERNQNIINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVVAQMALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGTSLSQTGLSKRLEMQHSSSYGLEYKRSYPTNSLTRSHQTTTLKRNNTNSSNSSHLSRNQSFGRGDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT
Protein: A disintegrin and metalloproteinase with thrombospondin motifs adt-2 (Q7Z292)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGASSEQQFCNEQACASSSANDWGTWSGWSQCSVSCGAGVKRRTRTCRTGNCPGNYKESAICNDRDCENKNAAWGGWGYWSSCSETCGDGVRKRVRKCYGSGNCDGQQYEKQYCNLRVCDFRRKF
Protein: Unc-13, isoform G (X2J9E1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTHYVRHDYFHNTQNGALSSDTSRISYSQISYETQPSREYFSESYALSNQGPEECSRVSHLNSDTVLTTVDNSNNSYGYDYLECYGANIQCDPEEDSVDNWNENTSVVADQYGLGHNNLNCTSSKLLPKLPNIENGRGSSNACAPQMDVKFNTKGMCIKIDHSYGVCMAKAHDFVGRLSPSDYQNILGNNLNGYAGCAYSSTFLDNAMSSAPLRVLPQSPRCSSYLGRNIIGFNADAAQRDGRGFDTDQTDAMGSESSTYEVYEKMQRPYTSMLPLDYSDYQEGCYNTDNLSTYSDTPPSNNTQLKRQMQRKISLMMAMTTASVIASGEIRVPVHSKQSKKSTEIQTDSIIGNTISTNAAARDLDRCLATESCEVIVDTRDSGSVTSFPSSAVTAITKTRKLPKVLPTPLCKSSRHPITIATDALSSSYTSDPLPEKSHRPKQLPKLPISLPQSNDRASLNSNWATPPAPDALPFNSFDHKSASSPTPTTTITKDTETTSYLVETDFIGARHNALYQYDSKEPNIVFSDKSVEAEHSPTWTPLSPIQSKQSPCPPVALPSNIMQNVSLTCHLPEIEATRSDIEREPESSSIEPILEIEKLADPYSGPGSALFNISEYLKPYTLNKPILSEEKKNHIANAASTSTTTPLNITSDDEFSSYSNKWTSTCVNFQPLDVESSLNISLKVNAGTNQAELLMTPLKSSTPLFISSNGTSDNFNLRKSSPPDSAFTTTVNVNSFETVLVSGSQTASPSPSNLKSPPSIAPLLSYSDYMKQFELPELPQPIMDLSENDTATQSDSFNVINNTLTNADNLNSYNQMDVESKSSLQLPSYSSESFDPCSVPSFSIKNKEYKIVEKLDSLSNVESVESPKTLVSPVNPLNCSKLLPGTESIVSNDVAFDDTFYDSFNVDIKELTAFVDHVAPEDGLYNFPNDKTSVEFSFDKTEDTIDMNQNLSSGECGYYKPSQAQQKASVVASAASSVLDGISKGLKGGLDGVFSGVSSTVDVTQSNPSSKRGFSFNLASKIVPSVGGLLTSTSSTSIKQTGSETNPTLILISPENVSSRNSNYIPTTSPSCTQKNGEENLYSATVHNKSTKSNSYYNEVGEISSTLVRNVCDSYDNSYDEMILTNEMVNIGMLDSESEFGLIENSYSYQVPDNEQIDSVNSYNNKTQNVTNNGIEKANTKNKPVPLHDPPTKKASTVGMFGSILGKAAAAVQSATQAVNQSASSVASVVAQKPTIVPRTNNVLLLSSVCSPNEIKRNSSSVEFDSEYGYQMPDVESLSSHYANTGGDYDNSNMKIHEFGTYADDRPYADYHTNGNQSQFKEEAVIPGEPEVINTNILPIGPQATGKKLPTVNGKSALLIKQMPTEVYDDESDTDELDVSPSTGKVPSYSIYSEQEDYYMDLQQTTPSIQPNGFYEQVNNGYDYREDYFNEEDEYKYLEQQREQEEHNQPKNKKYLKQAKISKIQPPSLDFIDVGQDDDFIYDNYHSEDDSGNYLEGSSSGSVGPIEGSIIKVDSNIEASFASLNKKSDSFTPTNDSLQKHDTVIGESTTKLTRLRTEKMCPDVDEEDENLSDHVSDLTDLSKLISQKKKTLLRGETEEVVGGHMQVLRQTEITARQRWHWAYNKIIMQLNNGGGPGEVGLRTNGHPGDNPFYSNIDSMPDIRPRRKSIPLVSELTMAATKRNAGLTSAVPRATLNDEDLKMHVYKKALQALIYPISSTTPHNFLLWTATSPTYCYECEGLLWGIARQGVRCTECGVKCHEKCKDLLNADCLQRAAEKSSKHGAEDKANSIITAMKDRMKQREREKPEIFELIRAVFSVEEKSHAGHMKAVKQSVLDGTSKWSAKIAITVICAQGLIAKDKSGTSDPYVTVQVSKVKKRTRTMPQELNPVWNEKFHFECHNSSDRIKVRVWDEDNDLKSKLRQKLTRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHYLCEENTGMVKLPTQKGDDAWKLYFDEIPEEIVDEFSMRYGIENIYQAMTHFHCLSAKYLCPGVPAVMSTLLANINAYYAHTTASSAVSASDRFAASNFGKEKFVKLLDQLHNSLRIDLSMYRNNFPASSPEKLMDLKSTVDLLTSITFFRMKVQELSSPPRASTVVKDCVKACLRSTYQFLFENCYELYNREFQVDPNEAKRAPDDHEPKLDSVDFWHKLIALIVSVIDEDKNSYGTVLNQFPQELNIGQLSASSMWHLFAVDMKYALEEHEQHRLCKSSAYMNLHFRVKWLYSNYVKEVPPYKGAVPDYPAWFEPFVMQWLNENDDVSLEYLHGAFKRDKKDGFQKSSEHALFSNSVVDVFTQLTQCFDVVSKLECPDPEIWKRYMRRFAKTIVKVLIAYADIVKLEFPEHMKDERIACILMNNIQQLRVQLEKMFESMGGDKLEEDAANILKELQQNLNSALDDLASQFAISLEPRITQSVRELGDMLLSIKGGSGTLAAGNLAAQRNAVAVEADEVLRPLMDLLDGSLTLYAQSCEKTVLKRLLKELWKIVMRILEKTIVLPPMTDKTMMFKHLTDNAKNLASNAKIEDMGRLFKSHMAGKQDVKSALSGVMDISKEVEKNLSPKQCAVLDVALDTIKQYFHAGGNGLKKTFLEKSPELQSLRYALSLYTQMTDTLIKTFISSQVHEVDLENSEESVGEISVQIDLFSHPGTGEHKVNVKVVAANDLKWQIPSGMFRPFVDINLIGPHLQEKKRKFATKSKSNNWSPKYNESFSFTIGNEEQLDFFELHICVKDYCFARDDRLVGVAVIPLKDISEKGSVACWLPLMRRIEMDETGWTILRILSQRNNDEVAKEFVKLKSEIRQEPTMGT
Protein: T. brucei spp.-specific protein (Q38C04)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTISTPVGIFEYKFLLFLPNFHLWVPELCFTAVVLHSNATNVHIKMCMCVRKGCTRNKKKKTGGTGESYIVTLLFFKLRIVHLLLFIPPLQNFFLLLKMVVAAIATGFALFLLTFCLTVLLEKFVPQCVPPFPPLSPPSIGFWRFLMFVRTPSRKTRSLANAAEPLHPLLWIPSVAQPFLG
Protein: Pre-mRNA processing factor 31 (E7ESX0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYH
Protein: Recombining binding protein suppressor of hairless-like protein (Transcription factor RBP-L) (O08674)
Organism: Mus musculus (Mouse)
Function: Putative transcription factor, which cooperates with EBNA2 to activate transcription.
Subcellular location: Nucleus {ECO:0000269|PubMed:9111338}.
Interaction partners:
- Mastermind-like protein 1
- Pancreas transcription factor 1 subunit alpha
- Mastermind like transcriptional coactivator 2
- Mastermind like transcriptional coactivator 3
- Neurogenic locus notch homolog protein 2
- Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 3
- Nuclear receptor corepressor 2
- Corepressor interacting with RBPJ 1
- Neurogenic locus notch homolog protein 4
Sequence:
MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSALPRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT
Protein: Venom prothrombin activator notecarin-D1 (vPA) (EC 3.4.21.6) (Venom coagulation factor Xa-like protease) [Cleaved into: Notecarin-D1 light chain; Notecarin-D1 heavy chain] (P82807)
Organism: Notechis scutatus scutatus (Mainland tiger snake) (Common tiger snake)
Function: Snake prothrombin activator that attacks the hemostatic system of prey. This protein is functionally similar to blood coagulation factor Xa.
Subcellular location: Secreted {ECO:0000269|PubMed:10779512, ECO:0000269|PubMed:12403650}.
Interaction partners:
Sequence:
MAPQLLLCLILTFLWSLPEAESNVFLKSKVANRFLQRTKRSNSLFEEIRPGNIERECIEEKCSKEEAREVFEDNEKTETFWNVYVDGDQCSSNPCHYRGTCKDGIGSYTCTCLPNYEGKNCEKVLYQSCRVDNGNCWHFCKRVQSETQCSCAESYRLGVDGHSCVAEGDFSCGRNIKARNKREASLPDFVQSQKATLLKKSDNPSPDIRIVNGMDCKLGECPWQAVLINEKGEVFCGGTILSPIHVLTAAHCINQTKSVSVIVGEIDISRKETRRLLSVDKIYVHTKFVPPNYYYVHQNFDRVAYDYDIAIIRMKTPIQFSENVVPACLPTADFANEVLMKQDSGIVSGFGRIRFKEPTSNTLKVITVPYVDRHTCMLSSDFRITQNMFCAGYDTLPQDACQGDSGGPHITAYRDTHFITGIISWGEGCARKGKYGVYTKVSRFIPWIKKIMSLK
Protein: Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48) (P28827)
Organism: Homo sapiens (Human)
Function: Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation. Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function.
Subcellular location: Cell membrane {ECO:0000269|PubMed:10753936}; Single-pass type I membrane protein. Note=Localizes in regions of cell-cell contact. {ECO:0000269|PubMed:10753936}.
Interaction partners:
- Catenin delta-1
- Catenin beta-1
- Cadherin-17
Sequence:
MRGLGTCLATLAGLLLTAAGETFSGGCLFDEPYSTCGYSQSEGDDFNWEQVNTLTKPTSDPWMPSGSFMLVNASGRPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAELAISTFWPNFYQVIFEVITSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVGGQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDEDLPGAVPTESIQGSTFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYELETPLNQTDNTVTVMLKPAHSRGAPVSVYQIVVEEERPRRTKKTTEILKCYPVPIHFQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPYKSYRIYFQAASRANGETKIDCVQVATKGAATPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDETHTMASDTSSLVQSHTYKKREPADVPYQTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG
Protein: Tnp_DDE_dom domain-containing protein (O18686)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MINIFNSPIDPSQLDEFAQGKQQEDGDEQIFDVKKRKPQVTYSGDGRRMLDGVVEKQHESNALWTTAITRGVANEWREEATGTRLQKTKRYLSKVTYDAQVLVRQTYRRHGTEILIATNVILLLLFLYICRLFPFNK