wanglab/gogpt-training-data huggingface dataset:
Protein: Xyloglucanase Xgh74A (EC 3.2.1.-) (Q70DK5)
Organism: Acetivibrio thermocellus (Hungateiclostridium thermocellum) (Clostridium thermocellum)
Function: Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG. Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose.
Interaction partners:
Sequence:
MVKKFTSKIKAAVFAAVVAATAIFGPAISSQAVTSVPYKWDNVVIGGGGGFMPGIVFNETEKDLIYARADIGGAYRWDPSTETWIPLLDHFQMDEYSYYGVESIATDPVDPNRVYIVAGMYTNDWLPNMGAILRSTDRGETWEKTILPFKMGGNMPGRSMGERLAIDPNDNRILYLGTRCGNGLWRSTDYGVTWSKVESFPNPGTYIYDPNFDYTKDIIGVVWVVFDKSSSTPGNPTKTIYVGVADKNESIYRSTDGGVTWKAVPGQPKGLLPHHGVLASNGMLYITYGDTCGPYDGNGKGQVWKFNTRTGEWIDITPIPYSSSDNRFCFAGLAVDRQNPDIIMVTSMNAWWPDEYIFRSTDGGATWKNIWEWGMYPERILHYEIDISAAPWLDWGTEKQLPEINPKLGWMIGDIEIDPFNSDRMMYVTGATIYGCDNLTDWDRGGKVKIEVKATGIEECAVLDLVSPPEGAPLVSAVGDLVGFVHDDLKVGPKKMHVPSYSSGTGIDYAELVPNFMALVAKADLYDVKKISFSYDGGRNWFQPPNEAPNSVGGGSVAVAADAKSVIWTPENASPAVTTDNGNSWKVCTNLGMGAVVASDRVNGKKFYAFYNGKFYISTDGGLTFTDTKAPQLPKSVNKIKAVPGKEGHVWLAAREGGLWRSTDGGYTFEKLSNVDTAHVVGFGKAAPGQDYMAIYITGKIDNVLGFFRSDDAGKTWVRINDDEHGYGAVDTAITGDPRVYGRVYIATNGRGIVYGEPASDEPVPTPPQVDKGLVGDLNGDNRINSTDLTLMKRYILKSIEDLPVEDDLWAADINGDGKINSTDYTYLKKYLLQAIPELPKK
Protein: Polypeptide N-acetylgalactosaminyltransferase 2 (pp-GaNTase 2) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2) (Q6WV19)
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers the monoglycosylated Muc5AC-3 as substrate. O-glycosylation modification of proteins by this enzyme might be important for cytokinesis.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Ras-related protein Rab6
Sequence:
MRRNIKLIVFVSIIWMFVMVYYFQSSTEKVENRALRLREVATAMQQYQDDSSSAAAASTARQWAPAGGGAGPGAAAGAAGSGADDPGGNVILIGSVKDFERNAVHGLKLNGIVALEETSQGLSGGTGGPGGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPDPQEVGQFRQDSTECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKHDDLCLTLVTFARGSQVVLKACDDSENQRWIMREGGLVRHYKINVCLDSRDQSQQGVSAQHCNSALGTQRWSFGKYA
Protein: G-protein coupled receptors family 1 profile domain-containing protein (L8EC40)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Transcription factor zip-2
- G-protein coupled receptors family 1 profile domain-containing protein
- Guanine nucleotide-binding protein G
- Mitogen-activated protein kinase pmk-1
- Beta-catenin/armadillo-related protein 1
- Glycoprotein hormone subunit beta domain-containing protein
- TIR domain-containing protein
Sequence:
MTCSTYRSIQLFSNLLIFILIILYLQTIECQNALSLAQTKHSCMALKAEDGEGCTCKQTKRYGQPECCCMGLIVSQLPTNLTADVGYLYLHNTSISVITPNFFDKFPSIRELEIDNSAHLEHIDGSSLSVLSKLRKLSVVKCPNLREISGKLLVNNTRIQNVILKNNGLATMPSLRMTDAHHVLLDRIDLSGNKIKFISDSKVRNVKARTVVLSENKLIEISGYAFTESQFLKLKLNNNPDLRSLSVDAFKNMAGLQTLDLSHTSIDTLPINGLKKLKTLILNDVPTLKSLPSVLSFTDLETAHFTYPHHCCLFKYVDDVTMNDNGKYQRNAKEIHKRICDKREQQKVARRRKRETSGIDFLDMLLKEWTDNSTYTGPDDADDDELPPFVEIGAEPCQSIGEEVQKYYSNITCYPQPDALNPCENIVGYPFLRIAVWVVCLAAIVGNIIVWALLGIVYEKRMRMHYLYMINMSVADMVTGIYLAVLAIADAKMSDEYYRHAVWWQTGWGCRAAGFLAVFASELGIISMFLIAFEMSYNTRQSFRGRRLSPKVGVLLMIGGWLFAIIMAILPWFDVSSYSESSVCLPLRAATIFDKSYLIFGLSFNFLAFAAMALSYGFIVKMLKENETREEDRALITKMTVLVVTDLICWFPTLFFGFTATIGFPLLSLSSAKFVLVFFFPINAFANPFLYVFFTEVIQHRVRSKTLPVIRRITTGPLNAASSLSNFYHSQPPGAHRRSRDEPTSPSGMHLAVTQVRQTTSLNSTPRGSDVSRASDGMLFDYDRRASASPRVSFDIPISPTTPRSDRKNRISLLKRIVSSIPEVSDLSEHSSESHHEHVPHPRRKLRSSLNRILALGRRQEGSADSGRGSIASSAGSRDQNERVSLTSNASSILSPLLSPTNSNILILPPEPSKNRRKSTPAIPLLVVSDCS
Protein: Zinc transporter ZIP13 (LIV-1 subfamily of ZIP zinc transporter 9) (LZT-Hs9) (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13) (Q96H72)
Organism: Homo sapiens (Human)
Function: Acts as a zinc-influx transporter.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:21917916, ECO:0000269|PubMed:31412620}; Multi-pass membrane protein {ECO:0000269|PubMed:21917916}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:23213233}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:31412620}.
Interaction partners:
- Zinc transporter ZIP9
- Zinc transporter ZIP11
- Proton-coupled zinc antiporter SLC30A5
- Zinc transporter ZIP1
- Proton-coupled zinc antiporter SLC30A2
- Zinc transporter 7
- Probable proton-coupled zinc antiporter SLC30A4
- Zinc transporter 6
- Proton-coupled zinc antiporter SLC30A1
- Proton-coupled zinc antiporter SLC30A9, mitochondrial
Sequence:
MPGCPCPGCGMAGPRLLFLTALALELLERAGGSQPALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFSLFVD
Protein: Exocrine gland secreted peptide 5 (Exocrine gland-secreting peptide 5) (A8R0T9)
Organism: Mus musculus (Mouse)
Interaction partners:
- Zinc finger protein 951
Sequence:
MTPLPVMFFLLTLLLPSMHTDGRVLTQTQNESTKSSNHKKNHKAVLDKTDRQDKGNKQAPEKVFCASIDDQTLVEDLATANQHKLILSKNKISQSNCCTQKHQVDPVNLNHMASRLQRTRVRHQEDSSKRKVIVGLDEFLDLVKKILISH
Protein: alpha-1,3-glucan synthase (EC 2.4.1.183) (Q4WFV3)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Interaction partners:
- Chitin synthase
- Chitin synthase G
- chitin synthase
- chitin synthase
Sequence:
MKWGWTGALLAWFATTTSCWPYDESLVGYNLNENKEAKSPVEYWGEWPDHKGKYFPSPENWRFPFYTLFLDRFVNGDPENDNINGTQFEHDISSNQMRHGGDVAGLVATLDYLQGMGIKGIYLAGTILMNQPWGADGYSTLDTTLLDQHFGNIDTWRNAITEIHKRGMYVIFDNTIATMGDLIGFEGYLNTTTPFSVKEHKALWKTDRRYVDFDIGNDYNSTCDYPRFWYEDGLPLPSEQADQLVGCYNSDFDQYGDIEAFGVFPDWQRQLAKFASVQDRLREWIPSVRERLIRHSCIIIASLDIDGFRYDKATQATVDALGEMSMAYRECARAVGKNNFFISGEITGGDYFGSIYLGRGRQQNQWLPDPSQGPKMTNESSAQYFLREAGHEALDSAAFHYSVYRTLTRFLGMDGNLAAGYDVPLDWVDMWRQMLRSNDLVNANTGKFDPRHMYGATNQDVFRWPTVQWGVERQLLGSYITTLLLPGIPLLLWGEEQAFYVLDATATNYIYGRQAMSPATAWRDHGCFSLNSSQYYKWPIQAGREGCHDDTVAYDHRDPSHPVRNILKHMYQLREQFPVLNDGYTLNNLSKSTFPVQYPGSNGTETETGMWSVSREANLEVQDFGSDDLNSPVWMVYQNDNHTVDYKFDCNSETDALIAPYPADTVVKNLFYPWDEFTLTAGPTKRTFGNATLPAGCYGNLTLKAFEFRAYVPKKLHRKPRPMITKFSPGHDVPIASTVAPDASENVPIELHFSEEMDCDGVTKSISLTSSTESLKVPSIDAGSVHCERITNFNTSWTAQIPSMWKWQATLTNVYNGIHQITVKEPKTSSGNASTNSTDHFLFRIGQVDNPMVFTRANYSTSLLHEYENGTLFIQHHAAGADKYRYSTNWGTTWSSWTKYHGGNDTIEELPWQGTKEQRWEGKHVRVEYWSGLTGSSDYYQEGDVGWPHQVPRRFPHIHFNGPFNQFGYDGGLPNKLKLDTTTGHWKYHFTYEWPAQAQINVWGMNPDGRPDQSWVLGDIDGDHVLDRMPPSSLSATMINITDLPPSPHLAWIISINDGTMRYTLEPTGDQSTQMAMYILFWIVPLLTGAVCVYVFMKSFYQVKFNQVGVSEKRTLIPLALRRKLKRARNGEGEAMNPLMRLANKSGFLQSATDLTAASGGSKRRMVLIATMEYDIEDWAIKIKIGGLGVMAQLMGKTLGHQDLIWVVPCVGGVDYPVDRPAEPMIVTILGKPYEVQVQYHILQNITYVLLDAPVFRQQSKSEPYPPRMDDLDSAIYYSAWNQCIAQTIKRFPIDLYHINDYHGSLAPLYLLPQTIPACLSLHNAEFQGLWPMRTEKEKEEVCSVFNLDKEITRRYVQFGEVFNLLHAGASYLRVHQQGFGAVGVSKKYGKRSYARYPIFWGLKKVGNLPNPDPSDVGEWNKEKALAKSEDPPVDQEFEAGRAELKRQAQEWAGLEQNPDADLLVFVGRWSMQKGVDLIADVMPAVLEARPNVQLICVGPVIDLYGKFAALKLDRMMKVYPGRVFSRPQFTALPPYIFSGAEFALIPSRDEPFGLVAVEFGRKGALGIGARVGGLGQMPGWWYNVESMTTAHLLHQFKLAIEGALNSKPEVRAKMRARSAKQRFPVAQWIEDLEILQSTSIRIHNKEASKSNNRPVTPTGPMTPRGLGTMSPTFPGSGTQTPVGTHSREASYVNLRQLSEIGPQQRDTIISYSNNNAGREMTEKPAPGLSRKLSLGVRSGPGHINRPGRRGQGQQDLALPDRRDGGDVSDIEEESDEDFIDQYYGDEEYTLTPEQAEEGRRLQNNPQSQSGRATPRELTRSSQFPSSPSVHSDMGLAPPTRPFLEPGNRLSSASVLSVDSVVGDKKDFKLQKVDPFFTDSHGEYARLFENSLENLNAANSETQLCIEEFLVKSEKEWFDKFRDAKLGRLNSPAPSVFRGKRGPSPVDSYYGDDASSRMSPDDEQSQEDDEFLLGKDYVPPTGLRKWMQLRIGDWPVYSLLLGLGQIIAANSYQITLLTGEVGQTAEKLYGIATTYLITSILWWFVFRYFKSIVCLSVPWFFYGLAFLLIGLAHFDHNEFSRGWIQNVASGFYATASSSGSIFFALNFGDESGAPVKEWVFRACVIQGTQQAYVIALWYWGSTLTKASSQGLLTAETNIANTWKMTAICVPITVFLWCVGLLMFFGLPNYYRQSPGKVPSFYRSVFRRKIVIWNFAVVIIQNFFLSAPYGRNWNFLWSSAHAKTWQIVILCIVFFGFVWAGFLFVLSHLSKKHSWILPVFACGLGAPRWAQIWWGVSGIGYYMPWVAGGLTGGALASRSIWLWLGVLDAIQGLGFGMILLQTLTRMHMCFTLIVCQVLGSIATICARAFAPNNVGPGPISPDPTYGASAVANAWFWIALIFQLLICAGFLLFFRREQLAKP
Protein: Dual-functional monooxygenase/methyltransferase psoF (EC 1.-.-.-) (EC 2.1.1.-) (Pseurotin biosynthesis protein F) (Q4WAZ0)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Dual-functional monooxygenase/methyltransferase; part of the gene cluster that mediates the biosynthesis of pseurotin A, a competitive inhibitor of chitin synthase and an inducer of nerve-cell proliferation. The PKS-NRPS hybrid synthetase psoA is responsible for the biosynthesis of azaspirene, one of the first intermediates having the 1-oxa-7-azaspiro[4,4]-non-2-ene-4,6-dione core of pseurotin, via condensation of one acetyl-CoA, 4 malonyl-CoA, and a L-phenylalanine molecule. The dual-functional monooxygenase/methyltransferase psoF seems to be involved in the addition of the C3 methyl group onto the pseurotin scaffold. Azaspirene is then converted to synerazol through 4 steps including oxidation of C17 by the cytochrome P450 monooxygenase psoD, O-methylation of the hydroxy group of C8 by the methyltransferase psoC, and the trans-to-cis isomerization of the C13 olefin by the glutathione S-transferase psoE. The fourth step of synerazol production is performed by the dual-functional monooxygenase/methyltransferase psoF which seems to catalyze the epoxidation of the intermediate deepoxy-synerazol. Synerazol can be attacked by a water molecule nonenzymatically at two different positions to yield two diol products, pseurotin A and pseurotin D.
Interaction partners:
Sequence:
MTRIRPDYDAIVIGAGFSGVRSLWELRRLGLTARCFDAGSDVGGTWWWNRYPGCRTDGEAWVYALKFLPELLEEWDFTERYPPQEEIQWYLSRVLDRYDLRKDIEFNTEVKSAHYSDHDSIWKITTASGKVATARYFLPATGITSIPKEPPFPGLQSFKGEVYQTSTWPAHEIEFENKRIGVIGTGSTGIQVITKLAPVAEQLIVFQRTPNYVIPAQNYPLDEKKREDIKKTFDATWDIAKRNLAGHAVKHSGRMVASAGGPEEIQRVFEDGWARGCYDFQLGTFDDSFMDPHANAVTSDFIRQKIRSIVRDGDTAEVLCPTYPFGARRPPCADGYYETFNRSNVKLVDIREDEIEVYDQGIKTASGAEYELDMIILALGFDTGTGAMNKIDIRGSQNRSLRESWTRRLETFAGVLVHGYPNMFVVCGPHLPAGNQPVSLEAFASWIGKTIEHMETNGLASIDVSNEAMDAWTTHVEQVWGGSFLAKHAHEQGSWFVGTNIPGKPSRIMFYFGGMVNLEPWLIKELETGWSSMSFTRLDGAEASNGVSKQTVGGVHVTPEMLESVQIPLEADKVGMTPAEKSKLVNAATAVYIDMAVEEMRSRGLAPKADYRVHWWKVMQDFVDSGEGQRVLQETSLTNQELERVIAKLGIEGEVIARMGPEIVNILTGKTHALAHIMRDDLLFRVYLSDEGRRANRYMAEYARLLTSQRRDIRILEIGAGTGGTTSEVLNLCSPNGESFCAEYMYTDLSPGFFNAAKTTLKKWESHLAFQVLNIEDDPAGQGFKEHTYDLIIAANVIHATARLTNTLSNVHKLLKPGGVFGLVELTRLTPFYNLTFGSLSGWWAGVDEGRTESPLQSPQQWNSLLKQTGFSGVDLAAYDLPGPERHSCLLLSTALSNSVTTNGH
Protein: Gem nuclear organelle associated protein 4 (I3L4M4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLSQFSAMAHKYLPALDEFPHPP
Protein: Nicotinamidase 3 (AtNIC3) (EC 3.5.1.19) (Nicotinamide deamidase 3) (Q9FMX8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Prevents the accumulation of intracellular nicotinamide, a known inhibitor of poly(ADP-ribose) polymerases (PARP enzymes).
Interaction partners:
- Nicotinamidase 1
- Nicotinate phosphoribosyltransferase 1
- Nicotinate phosphoribosyltransferase 2
- Nicotinamide adenine dinucleotide transporter 2, mitochondrial
- Nicotinamide adenine dinucleotide transporter 1, chloroplastic
- Peroxisomal nicotinamide adenine dinucleotide carrier
- Quinolinate synthase, chloroplastic
Sequence:
MASSSTRKYETRKRDPNSKIAALLVIDMQNHFSSMAKPILNNVLTTIDICRRASVPVFFTRHNHKSPTDHGMLGEWCNGDVILDGTTDSEIIQEIQGQVTGPDEMVEKNTYSAFNKTRLQENLEKIGVKEVIVIGVMTNLCCETTAREAFIKGFRVFFSTDATATFNEELHEATLMNLAFGFAYLVDCDKLRRSLLGN
Protein: Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152) (P16410)
Organism: Homo sapiens (Human)
Function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18468488, ECO:0000269|PubMed:28484017}; Single-pass type I membrane protein {ECO:0000269|PubMed:18468488, ECO:0000269|PubMed:28484017}. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalization.
Interaction partners:
- T-lymphocyte activation antigen CD86
- ICOS ligand
- T-lymphocyte activation antigen CD80
- Programmed cell death 1 ligand 1
- Inducible T-cell costimulator
- Programmed cell death 1 ligand 2
- Programmed cell death protein 1
- Ig-like domain-containing protein
- Galectin-9
- T-cell-specific surface glycoprotein CD28
Sequence:
MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
Protein: Ethylene-responsive transcription factor ERF113 (Protein RELATED TO AP2 6L) (Q9LYU3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator involved in the regulation of plant development and tolerance to abiotic stresses. Acts as positive regulator of tolerance to waterlogging stress. Delays waterlogging-induced premature senescence by regulating stomatal closure and antioxidant enzyme activity. May function through ABI1-mediated abscisic acid (ABA) signaling pathway. Involved in tissue reunion of wounded inflorescence stems. Required for the division of pith cells in the reunion process, which is dependent on polar-transported auxin and the wound-inducible hormones ethylene and jasmonate. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366}.
Interaction partners:
- NAC domain-containing protein 71
- Aberrant root formation protein 4
- NAC domain containing protein 64
Sequence:
MVSALSRVIENPTDPPVKQELDKSDQHQPDQDQPRRRHYRGVRQRPWGKWAAEIRDPKKAARVWLGTFETAEEAALAYDRAALKFKGTKAKLNFPERVQGPTTTTTISHAPRGVSESMNSPPPRPGPPSTTTTSWPMTYNQDILQYAQLLTSNNEVDLSYYTSTLFSQPFSTPSSSSSSSQQTQQQQLQQQQQQREEEEKNYGYNYYNYPRE
Protein: serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (Q95TC0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRKEVMQEVAQLSQFDEELYKVVGKGSEKAEEVGIDEKYLIATSEQPIAAYHRDEWLPESSLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKVEQFVLTSPHDNKSWEMMDEMIGNAEQFCQSLGIPYRVVNIVSGALNHAASKKLDLEAWFGGSGAYRELVSCSNCLDYQARRLLVRFGQTKKMNAAVDYVHMLNATMCAATRVICAILETHQTETGIKVPEPLKKYMPAKFQDEIPFVKPAPIDLELAAAEKQKGKKEKTKKDPAAG
Protein: DM1 locus, WD repeat containing (Dystrophia myotonica-containing WD repeat motif, isoform CRA_a) (G5E9A7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLIKKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFLEDCIITACQEGLICTWARPGKAGISSQPGNSPSGTVV
Protein: Cysteine protease (EC 3.4.22.-) (Q9VPW2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU363115}.
Interaction partners:
- Autophagy-related 8a, isoform A
- Autophagy-related 8b, isoform A
- Autophagy-related 1, isoform B
- Ubiquitin-like-conjugating enzyme ATG3
- Ubiquitin-like modifier-activating enzyme ATG7
- Autophagy protein 12-like
- Autophagy protein 5
- Autophagy-related protein 9
- Autophagy-related 18a, isoform E
- Autophagy-related 16, isoform F
Sequence:
MLVGLSDQLARIMESVFEAYLGPDSVLASAVGQAVGSGEPEDIPRRNTDVWVLGKKYNAIQELELIRRDIQSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTPDCRDATYLKIVNRFEDVRNSFYSIHQIAQMGESQNKAVGEWLGPNTVAQILKKLVRFDDWSSLAIHVAMDSTVVLDDVYASCREGGSWKPLLLIIPLRLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTAAAEQDYDETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLKEEVLSLCSPALFEISQTRAVDWDTTEDIDWPTMPDIDWPAGTSDSDSFAIVEESGRDSDAGCSGAIGSGKKPSERAVI
Protein: Minichromosome loss protein Mcl1 middle region domain-containing protein (Q57YM6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MRSNGAVHISNDTFAASTRDHTNGVFLVTSKIVEGRVCHRPLERHVCFGHCGDREEGKQKDSQYSFHASSDGSRVVSISANGSKHYCIGVEDGRVCEFTVQHPVVSVGWHPVSKSLLLLLLSGGKLLLLDTDKVTLGVGFQGDECVCLHSLVATCRQGSGKRDSQETAKAGTLVKAPFNLNRCGLSTPDPTSEGTVSKKLHGTIEGMRSGLGGQVQEVVTKNRRGKKGIIKRGESANERYALAQIDATQSPRVDGCSDIVGMCIIPPSRSLPVMLVLLCRNGDVFSVKLNKDGMPASLSKEYDGSVGAAFGEAQDMQMDSVLRPCVHYLVRRDSSSCGLAGVPLAVGTSLLDEDVGLRIIYVMYSSGTLGGYLFDEPDVLCRDPMRQQADVSVVLGAAVPCDHRLLHDHVNACRLVSIHSCGNATLIRYGDEVYLCVWPVWSRAAAGWVYRTENTEGFQRLPTIARDAKVPEPVALRVPYSTHGANIAVGVNDILIFPEMTETAAMCDFEKKVTIVKILSLVLIAIYARSEKFVLAPDSTEDAVDEGNDNEVDGSRSKGGNVVQTSLEELLGLIPTLCRQWLCGYPREVVDSSTAAVVKGVHNMHMRFRERQTKQLEREQRLWKRVEALQQKRDEVADAVAESTDTLCDAIVHRGGVSELYAANKRMGKIHEILSTLNSEVERRRKEKSKV
Protein: ATPase PAAT (EC 3.6.1.-) (Protein associated with ABC transporters) (PAAT) (Q9D2Q3)
Organism: Mus musculus (Mouse)
Function: ATPase that regulates mitochondrial ABC transporters ABCB7, ABCB8/MITOSUR and ABCB10. Regulates mitochondrial ferric concentration and heme biosynthesis and plays a role in the maintenance of mitochondrial homeostasis and cell survival.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9H8K7}. Mitochondrion {ECO:0000250|UniProtKB:Q9H8K7}.
Interaction partners:
Sequence:
METAIEDAGLDRGPTLTSSWDAACGALTQSLFLTRTGPRAQDLDFEQLLEPPAPSQDPVSLKSSLSPRDENPCFIYLNCGPNGGEEILSVGVLSSARNMEVYLGEEYCGTSRGKTACTVLDDSEHEKILLYKKYLKLDSPTHACKIKLLSFGEKQCVLVSKVVVHLRPRSADPSPRSAALGSRIDLDNIQTIMESMGSRLSPGAQQLMSMIRFQQQNRLPIGDQLQSVLGSAGHKHLMALQSSPSPAVLDKASSTPFPFRTGLTPSAITENLKALIDKSAQPSGEGNTTNHDEGHLMPQNHSLESDLKNAVSSFLPKKASGSSSVPSSELLPFLQNLCSQVNHLRVGHNARWQENISKPREGMVGVPMEEQPVCSYLEKILSKNMELMEKKLMDHIDERIYQLQEHIDAKMALLVDLLRGPNSPPPGMPLRHYDSRERLSNGER
Protein: Mitochondrial RNA binding protein (Q38F80)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQSLVSLRTRVQSVAVSDAFSSLQSCHRPITTPAAKPAAGAHLREQTKATDTVVDSTKDQRHHSKGRGVAGVRNRGGPYRRQAQAWNTSGKSGLNLPESSAPVLFPLGNGLEVTLPHDTFAWKTRGAPAGIAERNQSAGEHGGKFVGDGGKSLHVCDSNGCGTDRQAEVAIMHLNESGELISAIFAVPSLKGSEKLQKALEEWPELLHRLRADSLPVILGSSGESPPTARSIIRAFQILTEALGSLDSISQNSGLRAEQLFPADLVAALWRALPPIHEYIKRTAVDSPQPSGGTDSDNGVNESLRDDEVALPATPELPSSPMKAFKVARRALALRAREVGDVLPPSLLVQVLLSIEKCGALSDDIIGPMGTRLLERYDRALVAHGGPQRVASNHQLSTRFVSRTMNSYDLPFSDEDSVSFARLLGRAQVVDHFQLHRLVHTILLPSVVRALRSNALSLTELFELTACYARYAVCGRPVVQVTELWMSHVPQMSLEQCVKLLNIVSPNRQRINGKKRFTSGKTRQTLATGAEEDYFPLVGAVLERAVWLCVRETQIVNNTDTTEQIIAVADEDCGVLSPTCLTKFMCALTRVNAERWAEVYMVVASVIEKKLELFSITDVMSMAKSIIQRGSNIPYHTFHAQLARFLLQAEAALSDVKVASVALVSAALMLPAPPLSLSKVKEAHFLQPPTNSVPAPTCAGEDKPLREMGSCTLEHSSALAIFRKHGTRLGLHSFVAGMCATPLEELPRRSQERVIVHFTAIASAIGVAWLARGIAALTSRIPDSVDPLSVQRWFSRFTVVDVTRQLDLEHAAMLLNVLSHENYSRESALAKRAITNRVARLLLQDDVSLHSIVLIAPALQRADVFFPHLYSRLCRVLLSTVQKAPFDALLPAFYVAADEFTRCKHHNGGTFRDVWELLRTRVIDDAAVSLTTEDVIVALNGFAALDVGDYPVFSVLLHRLWVSYKEVASQCGGEEGGTSAVSGSLTPTRWVDKVLSGCTPSAVAVLACSLTHLGDGEVVDTFMPWVLLRLRQVVRDIFPIDVLHLMPALLANFAKAASRAENSLNPTHWLNIDANCSLLHAVYDACRELFLQMYGEARKDSGEGVDGVRREDWIPKVHVSVSSVPHRHFAELLIALCRAGVQDETVVMACAPRTTQRCCAVLPMAELVDLTMALCFHLHLHPQETDQCDTSKEQSIKHTDGTDGDVVGNPPFAESEGTGNGGTDAVKSASLQAITPNQQLLLPALNALWERVEELSLPQVDALVRCLRHYYGEKVDTDFLFRLQNHRAAVEEMRRSRQQRRGEKVMKGEATLTVDAAKPRNSAEEQGRREEGTQLQLTAEDLFVC
Protein: At5g04420 (Galactose oxidase/kelch repeat superfamily protein) (Q9LZ83)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- UPF0235 protein At5g63440
- Probable cysteine protease RD21B
- At1g09850
- Cysteine proteinase RD21A
- Probable cysteine protease RD21C
Sequence:
MEEIRKEIDVGDWHSNLAHDEWTPLPVSGSRASARYKHAAVVVDEKLYIVGGSRNGRYLSDVQVFDLRSLTWSSLKLKTESSSADNIQEDDGSSLREAFPAISDHRMIKWGNKLLLIGGHSKKSSDNMLVRFIDLETHSCGVIDVFGNVPASRGGHSITLVGSRVLVFGGEDKNRRLLNDLHVLHLETMTWDVVETKQTRPVPRFDHTAATHSDRYLLIFGGCSHSIFYSDLHILDLQTMEWSQPHVQGDVVTPRAGHAGITIDENWYIVGGGDNSTGCLETLVLNMSKLVWSTSTHVEARHPLASEGLSVCSASVFGENILVAFGGYNGKYNNDIFVMRLKPGESSHPKIFKSPAAAAAAASVTAAYAIAKSDKSDYPPPANPTLNGNGNSLPERDIRNRIDTIKEEKRALESSIAETQVENAKLREKIDEVNSSHTELSQELQSVEGQLISERSRCFKLEAQIAELQKALESGQSIEAEVEMLRRQRSASDEEEDGTVQRQGSAGVWGLFGR
Protein: P-loop containing nucleoside triphosphate hydrolases superfamily protein (Q8L5Y4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR038901}.
Interaction partners:
- Pre-mRNA-processing-splicing factor 8A
- Tetratricopeptide repeat
- ATPase E1
- DExH-box ATP-dependent RNA helicase DExH12
- Cell division cycle 5-like protein
- AT3G18790 protein
- Pre-mRNA-splicing factor SPF27 homolog
- Protein ABA AND ROS SENSITIVE 1
- Peptidyl-prolyl cis-trans isomerase CYP18-2
- Pre-mRNA-processing factor 19 homolog 2
Sequence:
MTKVYGTGTYDFKRHRVAEYPLELPSHPAEKPLESKPGSNLPSSITLSEIQQDRLTKIAEESWIKTGGKLPEKPFDPEVVKEIYVTELKVTSGRKPVPLQRVMILEVSQYLENYLWPNFDPETATFEHVMSMILMINEKFRENVAAWICFHDRDDLFKKFLQKVLRLKEGRDLTIAEKTNYLVFMINAFQSLEDAVVNEIVLSLAGLQSWHSLSYGRFQMELCLQPDLIKKWKRSSKKWAAEAKSKGEKFDLSSSPEANFVRGLIEEFVEVLDHGVFADEVDDTAGSQLVDDSSVLYCERFMEFLIDMLNQLPTRRYLRPLVADIAVVAKCRLSALYKHEKGKLFAQLVDLLQFYEKFEIKDHDGTQLTDDEALQFHYDRFMAFQLLAFKKIPKLQDLSLANIGSIHKSSDLRRRLSVLSLEDLRDVVCSKLKLVSRHDPWADSKDFLTEVVVSSFEKQQSQKEAINALPLYPNEQIMWDESVIPSINYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIREDIQEAVPHLLAHINNEGDTAFRGWSRMAVPINDFKIAQVKQPNIGEEKPSSVTAEVTFSIKSYRTQIRSEWNSLKEHDVLFLLCIRPSFEPLGPEEADKATVPQRLGLQYVRGCEIIDIRDEEGNLMNDFTGRVKRDEWKPPKGEMRTVTVALDAAQYHIDVTDIAEKGAEDVYGTFNVLMRRKPKENNFKAILESIRDLMNEYCIVPEWLHNVFLGYGNPSAAQWPNMPNLLEIVDFKDTFLNANHLSESFSDYEVSFINAEGAEALDPSPPFRITLPKTLKGNGAISGNKISEVNPADNVNMVDASPKEKLIVEAYTPPDPGPYPQDQPKQNSVKFTPTQVGAIISGIQPGLTMVVGPPGTGKTDTAVQILNVLYHNCPSQRTLIITHSNQALNDLFEKIMERDVPARYLLRLGQGEQELATDLDFSRQGRVNAMLVRRLELLSEVERLARSLQLPEDVGYTCETAGYFWLLHVYSRWELFLAACAGNEDNQSFVRDRFPFKDFFSDTPKPVFNGESFEKDMRAAKGCFSHLKTVFQELEECRAFELLKSTADRANYLMTKQAKIVAMTCTHAALKRRDFLQLGFKYDNLLMEESAQILEIETFIPMLLQRQEDGHARLKRCILIGDHHQLPPVVKNMAFQKYSHMDQSLFTRFVRLGIPYIELNAQGRARPSLAKLYNWRYRDLGDLSIVKEAPIFQRANAGFSYEYQLVNVPDYEGRGESTPSPWFYQNQGEAEYIVSVYIYMRLLGYPANKISILTTYNGQKLLIRDVINRRCVPYPFIGPPSKVTTVDKFQGQQNDFILLSLVRTRFVGHLRDVRRLVVAMSRARLGLYVFCRRSLFEQCYELQPTFQLLLQRPDRLGLNFNENTAYTDRVVEEVENSYLVHDVEEMAHIVDDRMNKFYQAQGAYEQYQNNMAQMEDGNHDMESDSVVDGDESEKNMQQLNQSPDIDGELSKEVVGMEVDNNGFSSENGKADEKN