wanglab/gogpt-training-data huggingface dataset:
Protein: (thale cress) hypothetical protein (RLK) (A0A178UAF6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MMTTVAADLHRYLFLITVFLFFLCDKTSLALTTDGVLLLSFRYSIVDDPLYVFRSWRFDDETPCSWRGVTCDASSRHVTVLSLPSSNLTGTLPSNLGSLNSLQRLDLSNNSINGSFPVSLLNATELRFLDLSDNHISGALPASFGALSNLQVLNLSDNSFVGELPNTLGWNRNLTEISLQKNYLSGGIPGGFKSTEYLDLSSNLIKGSLPSHFRGNRLRYFNASYNRISGEIPSGFADEIPEDATVDLSFNQLTGQIPGFRVLDNQESNSFSGNPGLCGSDHAKHPCRDGEATSPPPSPTPNSPPALAAIPNTIGLTNHPISSKTGPKSKWDHKPVLIIGIVVGDLAGLAILGIVFFYIYQSRKRKTVTATSKWSTSSTDSKVSKWYCLRKSVYVDGDCEEEEEESETSESESDEENPVGPNRRSGLDDQEKKGTLVNLDSEKELEIETLLKASAYILGATGSSIMYKAVLQDGTAVAVRRIAECGLDRFRDFEAQVRAVAKLIHPNLVRIRGFYWGSDEKLVIYDFVPNGSLANARYRKVGSSPCHLPWDARLKIAKGIARGLTYVHDKKYVHGNLKPSNILLGLDMEPKVADFGLEKLLIGDMSYRTGGSAPIFGSKRSTTSLEFGPSPSPSPSSVGLPYNAPESLRSIKPNSKWDVYSFGVILLELLTGKIVVVDELGQVNGLVIDDGERAIRMADSAIRAELEGKEEAVLACLKMGLACASPIPQRRPNIKEALQVLERFPVHSSQQ
Protein: Putative F-box/FBD/LRR-repeat protein At1g78760 (Q9ZV94)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDTGGDEKRARRSEEDRLSNLPESLICQIMLNIPTKDVVKSSVLSKRWRNLWRYVPGLNVEYNQFLDYNAFVSFVDRFLALDRESCFQSFRLRYDCDEEERTISNVKRWINIVVDQKLKVLDVLDYTWGNEEVQIPPSVYTCESLVSLKLCNVILPNPKVISLPLVKVIELDIVKFSNALVLEKIISSCSALESLIISRSSVDDINVLRVSSRSLLSFKHIGNCSDGWDELEVAIDAPKLEYLNISDHSTAKFKMKNSGSLVEAKINIIFNMEELPHPNDRPKRKMIQDFLAEISSVKKLFISSHTLEVIHDLGCELPLFRNLSSLHIDFEDHTLKMLSTFLQSCPNVKSLVVEFKDSSKEDGDRVLSIPRCFFTTLEYVKIERPITGEARGMKVVSYILENSPILKKLNLCLNSSREKSESVILKELLTIPRLSTSCKVVVFEPRSCWVLG
Protein: PX domain containing serine/threonine kinase like (PXK) (W5RWE6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSGISALPPPPPPPPPPAAPLPPASTEAPAQLSSQAVNGMSRGALLSSIQNFQKGTLRKAKTCDHSAPKIG
Protein: Pectinesterase (EC 3.1.1.11) (Pectin methylesterase) (E7CIP7)
Organism: Sitophilus oryzae (Rice weevil) (Curculio oryzae)
Function: Pectinesterase which probably plays an important role in the digestion of plant cell walls.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MKIIVLLLLAVVLASADQTAPGTASRPILTASESNYFTTATYLQGWSPPSISTSKADYTVGNGYNTIQAAVNAAINTGGTTRKYIKINAGTYQEVVYIPNTKVPLTIYGGGSSPSDTLITLNMPAQTTPSAYKSLVGSLFNSADPAYSMYNSCASKSGTIGTSCSTVFWVKAPAVQIVNLSIENSAKNTGDQQAVALQTNSDQIQIHNARLLGHQDTLYAGSGSSSVERSYYTNTYIEGDIDFVFGGGSAIFESCTFYVKADRRSDTAVVFAPDTDPHKMYGYFVYKSTITGDSAWSSSKKAYLGRAWDSGVSSSSAYVPGTSPNGQLIIKESTIDGIINTSGPWTTATSGRTYSGNNANSRDLNNDNYNRFWEYNNSGNGA
Protein: Annexin A6 (67 kDa calelectrin) (Annexin VI) (Annexin-6) (Calphobindin-II) (CPB-II) (Chromobindin-20) (Lipocortin VI) (Protein III) (p68) (p70) (P14824)
Organism: Mus musculus (Mouse)
Function: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
Subcellular location: Cytoplasm {ECO:0000250}. Melanosome {ECO:0000250}.
Interaction partners:
- Annexin A2
- Prolow-density lipoprotein receptor-related protein 1
- Annexin A1
- Dysferlin
Sequence:
MAKIAQGAMYRGSVHDFPEFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGVGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKLCGGDDDAAGQFFPEAAQVAYQMWELSAVSRVELKGTVCAANDFNPDADAKALRKAMKGIGTDEATIIDIVTHRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKTLIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGNREEGGENRDQAQEDAQVAAEILEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEHVIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFMKALLALCGGED
Protein: G-protein coupled receptor 81 (Hydroxycarboxylic acid receptor 1-1) (C6EVZ7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MNNSSSVCCAFDAPILDEVLPPVLFSEFVLGLMGNGLALCMFFFHRDSWKPNSIYLAHLALADSLVLFCLPFRADYYRRGKHWVYGDAFCRVLLFLLAANRAAGIFFLTAVAVDRYLKIVHPLNRINQMGLRYALWVSVGLWALIIAMTVYLLADKHFYYRNNRTQCESFNICLGHNALSDWHNSFYVIQFFVPTFIVIYCSTCITWQLKGKTIDKHGKIKRAVRFVLAVALVFIICFFPSNVSRIAVWVLKSWHNECQYFQDANVAFYITVCFTYFNSVLNPVVYYFSSPAVSRSLRKIYMRMSGQKIEDEHEKNNHSSVTVSANVS
Protein: Ataxin 2 like (A0A0C4DGL7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
NKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE
Protein: Rho guanine nucleotide exchange factor 9 (Collybistin) (PEM-2 homolog) (Rac/Cdc42 guanine nucleotide exchange factor 9) (O43307)
Organism: Homo sapiens (Human)
Function: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10559246}. Postsynaptic density {ECO:0000250|UniProtKB:Q3UTH8}.
Interaction partners:
- Gephyrin
- Cell division control protein 42 homolog
- Neuroligin-2
- Gamma-aminobutyric acid receptor subunit alpha-2
- Glycine receptor subunit beta
- Sodium- and chloride-dependent glycine transporter 2
- Glycine receptor subunit alpha-1
- Protocadherin-19
- Gamma-aminobutyric acid receptor subunit beta-3
- Mitochondrial glutamate carrier 1
Sequence:
MTLLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDEVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNSARSVPPSYPPPQDPLNHGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK
Protein: Autophagy-related protein 8C-like (Autophagy-related ubiquitin-like modifier ATG8CL) (M1C146)
Organism: Solanum tuberosum (Potato)
Function: Ubiquitin-like modifier involved in autophagosomes formation (Probable). May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton (Probable). ATG8CL-mediated selective autophagy contributes to defense against the fungal pathogen Phytophtora infestans.
Subcellular location: Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:26765567, ECO:0000269|PubMed:29932422}; Lipid-anchor {ECO:0000250|UniProtKB:P38182}. Vacuole membrane {ECO:0000269|PubMed:29932422}; Lipid-anchor {ECO:0000250|UniProtKB:P38182}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8LEM4}.
Interaction partners:
- Protein JOKA2
- Cysteine protease
- Zinc ion binding protein
- TA4 protein
- Autophagy-related protein 3
- Ubiquitin-like modifier-activating enzyme ATG7
- MAP/ERK kinase kinase 3
- Serine/threonine-protein kinase
- Ubiquitin-like protein ATG12
- WD-repeat protein
Sequence:
MAKSSFKLEHPLERRQAEAARIREKYPDRIPVIVEKAERSDIPDIDKKKYLVPADLTVGQFVYVVRKRIKLSAEKAIFIFVKNILPPTAAMMSAIYEEHKDEDGFLYMTYSGENTFGSF
Protein: Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1) (O00214)
Organism: Homo sapiens (Human)
Function: Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.
Subcellular location: Cytoplasmic vesicle {ECO:0000269|PubMed:22246324}. Cytoplasm, cytosol {ECO:0000269|PubMed:22246324}.
Interaction partners:
- Calcium-binding and coiled-coil domain-containing protein 2
- CD166 antigen
- Tax1-binding protein 1
- Integrin alpha-3
- Tripartite motif-containing protein 16
- Podoplanin
- Integrin beta-1
- Galectin-3
- Integrin alpha-M
Sequence:
MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
Protein: DNA topoisomerase 3-beta (EC 5.6.2.1) (DNA topoisomerase III beta) (O96651)
Organism: Drosophila melanogaster (Fruit fly)
Function: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity). Weakly relaxes negative supercoils and displays a distinct preference for binding single-stranded DNA.
Interaction partners:
- Survival of motor neuron-related-splicing factor 30
- RecQ-like DNA helicase Blm
- DEAD-box ATP-dependent DNA helicase Fancm
- Crossover junction endonuclease MUS81
- GEO08380p1
- Replication protein A 70 kDa DNA-binding subunit
- DNA topoisomerase 1
- DNA topoisomerase 2
- CG9273 protein
- Salivary gland secretion 1
Sequence:
MKSVLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVMSLDFNKKYNCWDKVDPIQLFGCATEKKETNPKQNMRKFLAHEARGCDYLVLWLDCDKEGENICFEVMDAVKHVINNVYSDQVTYRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELDLRIGCAFTRFQTKFFQDRYGDLDSSLISYGPCQTPTLGFCVKRHDDIQTFKPESFWHLQLLAGQPEVTLEWARGRVFKKDIAIMLLNRVKEHKKATVESVASKEAYKSKPQALNTVELMRICSSGLGIGPFQAMQIAERLYTQGYISYPRTETNQYPTNFDLPAVLHVLKPSADFGEEARSILGDIQTPRKGKDAGDHPPITPMKLGNRSDFDRDTWRVYEFICRHFMGTVSRDLKYRVTTAKLSVGMETFSCTASVLIDAGFTKVMTWSAFGKDEPQPPFVQGTQVAINDVRLIESQTGPPDYLTESELITLMEEHGIGTDASIPVHINNICQRNYVHIENGRKLMPTTLGIVLVHGYQKIDPELVLPTMRTEVERMLTLIAQGSANFQDVLRHAIKIFKLKFMYFVKNIDSMDALFEVSFSPLAESGKAHSRCGKCRRYMKYIQTKPARLHCSHCDETYALPIGNVKVYREFKCPLDDFDLLAFSTGVKGRSYPFCPYCYNHPPFSDMPHLGGCNTCTNANCPHSLNTLGISSCVECPTGVLVLDCTLAPTWKLGCNRCDVIINCFKGATKITVEEAKCQECGAQQVNVVYKSDKSKFKDGSEEKSGCIFCSADFSHLVEKHRAVASRPVRSGGGFRGGKAGRGGGGMGGAAFGSGGAVTAGGGPNAGGGVRGSRVAKDKMGQLASYFV
Protein: Uncharacterized protein C320.06 (O59783)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MVLISNTLHCADAYSSADSKHVPLTLSTRRINLQSFQSISARNCGSDARVLDFVKSIDNDNSWKRRNLDSKRNIGSRKKNRFLNDLHILKQAADDPDEVVYKDLFTHRPAFGFLTVGDEFYKDGVNNISSLLTSSSNQRFNDNHHKSIVKRIRHEIKCYNSLQLVLLLDECLNNIMNEKLYAYDHDHSPAIYASESFNIKAEIDTSSFLETQRSYRIYMLIDCPSNPKATAFARYWMHLICSYYGIYTTSTQILSNKIMTLGVSKKRKHLSFKTLSELLNHDELTNINR
Protein: Protein matrimony (Cell cycle arrest protein D52) (Q23973)
Organism: Drosophila melanogaster (Fruit fly)
Function: Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings.
Subcellular location: Nucleus {ECO:0000269|PubMed:14573476}. Chromosome {ECO:0000269|PubMed:14573476}.
Interaction partners:
- CG5272 protein
- Thioredoxin-1
- Maternal effect protein oskar
- LD24340p
- Tubulin alpha-4 chain
- Serine/threonine-protein kinase greatwall
- Poly
- Serine/threonine-protein kinase polo
- Chorion peroxidase
- Deubiquitinase otu
Sequence:
MENSRTPTNKTKITLNRTPTLKERRWNTLKVNTSNVRCSTPIFGNFRSPNLSPIENMGTKGKSPVSPMRFATFKKVPTKVHPKQQQQQQHQHCHRTQLKPPPFVLPKPQEEIIEPEREIKSCSSPDTCSDDSNMETSLALESRRRSIKASNHSYVVNHAANVEQILMHMGLENYVTNFEEAHIDLVELASLERADLVKIGLNTDEDCNRIMDVLHTL
Protein: Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125) (Q8IWK6)
Organism: Homo sapiens (Human)
Function: Orphan receptor that may have a role in planar cell polarity pathway.
Subcellular location: Membrane {ECO:0000250|UniProtKB:S4X0Q8}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Adhesion G protein-coupled receptor L1
Sequence:
MEPPGRRRGRAQPPLLLPLSLLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRLDLTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCNILWMHRWVKEKNITVRDTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLPFQCMASYIDQDMQVLWYQDGRIVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNTHGSGIYPGNPQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLTNAVATARQLLAYTVEAANFSDKMDVIFVAEMIEKFGRFTKEEKSKELGDVMVDIASNIMLADERVLWLAQREAKACSRIVQCLQRIATYRLAGGAHVYSTYSPNIALEAYVIKSTGFTGMTCTVFQKVAASDRTGLSDYGRRDPEGNLDKQLSFKCNVSNTFSSLALKNTIVEASIQLPPSLFSPKQKRELRPTDDSLYKLQLIAFRNGKLFPATGNSTNLADDGKRRTVVTPVILTKIDGVNVDTHHIPVNVTLRRIAHGADAVAARWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQAASLLHPVVYTTAIILLLCLLAVIVSYIYHHSLIRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASICQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKRCQDPDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPNAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAANENGEINHQDSMSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYYPLDLVFSFVFGATSLSFSAFFVVHHCVNREDVRLAWIMTCCPGRSSYSVQVNVQPPNSNGTNGEAPKCPNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQCHANSLPLNSTPQLDNSLTEHSMDNDIKMHVAPLEVQFRTNVHSSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSVQNGLPKSRLGNNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNFEKPVSTTSKKDALRKPAVVELENQQKSYGLNLAIQNGPIKSNGQEGPLLGTDSTGNVRTGLWKHETTV
Protein: MIP07211p (RE61847p) (Regulator of cullins 2, isoform A) (Regulator of cullins 2, isoform B) (Q7JWH5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Cullin-5
- Elongin-B
- Elongin-C
- Cullin-2
- Ubiquitin-like protein NEDD8
- Protein gustavus
- Cullin 3, isoform F
- Potential E3 ubiquitin-protein ligase ariadne-2
- Cullin-4A
- Cullin-associated NEDD8-dissociated protein 1
Sequence:
MADDPENSVDRPTDDGDAGKPEKMFTLKKWNAVAMWSWDVECDICAICRVQVMDSCLRCQADNKRDVMGRQDCVVVWGECNHSFHHCCMSLWVKQNNRCPLCQQEWSIQRMGK
Protein: Calcium uptake protein 1 homolog, mitochondrial (Mitochondrial calcium uptake 1) (A2VEI2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (Probable). During development, required in alpha/beta or gamma mushroom body neurons to support olfactory intermediate-term memory in the adult.
Subcellular location: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:Q9BPX6}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9BPX6}.
Interaction partners:
- Essential MCU regulator
- Calcium uniporter protein, mitochondrial
- Mitochondrial calcium uptake 3, isoform D
- Mitochondrial proton/calcium exchanger protein
- Essential MCU regulator, mitochondrial
- Prohibitin
- AFG3 like matrix AAA peptidase subunit 2, isoform A
- Inositol 1,4,5-trisphosphate receptor
- Paraplegin, isoform A
Sequence:
MSVLRFLVTRQALAALTRPRTLNIIQNPAQIAYASTLCNQNSNHNAKDLTKSSANLSLMQTRGHKRFGHQEEKTPSVTKYFHMFILSLFLISVMDWGKVKRMLTPKVDADAGQRPSSAADVNGEDKSSESESEDSEDEEAGSDLHLHEGKKIREKVGFRERKIIEYENRIRQFSTPDKVFRYFATIQVPVADDRHEVYMTPTDFLTSMTPGMKQPDGLGLDQYRRYDPKSVGEQLNLHLEKNSIFYKLGSYGLITFSDYIFLLTVLSISRRHFEIAFRMFDLNGDGDVDCEEFEMVATLVRQQTSMGTRHRDHANTGNTFKGVNSALITYFFGPNMDEKLTIEKFLDFQEQLQREILSLEFERKEPNDEGNITEADFAELLLAYAGYPLKKKQKKLKRVKRRFRDHGKGISKQDYLDFFHFLNNINDVDTALTFYHIAGASIDQQTLQHVAKTVAMVNLSDHVVDVVFTIFDENNDNQLSNKEFISVMKNRVQRGLEKPKDTGFLKMMRSVFKCAKETKPVLLDI
Protein: Protein LAZY 1 (ZmLA1) (Protein CONTROLLING LEAF ANGLE 4) (ZmCLA4) (Protein PROSTRATE STEM 1) (B4FG96)
Organism: Zea mays (Maize)
Function: Involved in the regulation of shoot gravitropism, and tassel and ear development through the regulation of polar auxin transport (PAT) and auxin signaling. Acts as negative regulator of basipetal PAT, but positive regulator of lateral auxin transport. Involved in the regulation of shoot gravitropism and leaf angle through the regulation of cell development.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24089437, ECO:0000269|PubMed:24987012}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000269|PubMed:24089437, ECO:0000269|PubMed:24987012}.
Interaction partners:
- Knotted related homeobox7
- Protein LIGULELESS 1
- Protein LIGULELESS 1
Sequence:
MKLLGWMHRKLRQNSNDVFKEFNNAAGGTCNCITGLAASDPATFLATANEYFTADNDFTNNHPSSPAADLFTFGGSGLLTIGTLGIAAVAVSADADEVDYDVDADADSDFDDNDDTAGDDEDQVDSAVTPTFTYAAPPPIEDATVVEKAAVAVVEAIAEKDDDTTTEDDLMVVSAELEKVLGGRNSGTAGDLVASARVSFAMGVDCPLQGFLFGSPVSDAESRLEQPRDSNGGRRTSLGELFMRTRFAEEKVALVAVEEGEDGGDIGAGGERDDRKAGKGGGGHKTTKKRSAKDEKVPRGDGAQASATVTKSKFHKILQIFHRKVYPESAALARNLTKKSRKRGSGAYHKPEPAASKLRCLKEQRAPGFGCCASRASFGGAASPIDGDDDDELNGSKSGHWIKTDAEYLVLEL
Protein: Down syndrome cell adhesion molecule 1, isoform BP (A0A0B4K6R8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVIQSYESEADNEYVIRGNSVVMKCEIPSYVADFVFVDLWLDSEGRNYYPNNAAETDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIGARAPSFSSDYNSFSYARVVDQSFAMLCQAQAFPLPIMRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPQIRPFDFGDEASNSGETMGIQCTVIKGDLPINITWVLNNHTLNSGDLDVVIGRMSSKSSTLNIDYIAAEHRGVYTCLARNQAGESSYSAELKVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
Protein: Alpha/beta-Hydrolases superfamily protein (O23227)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g51840
- Probable lysophospholipase BODYGUARD 4
- Transducin/WD40 repeat-like superfamily protein
- Alpha/beta-Hydrolases superfamily protein
- Phospholipase A2-alpha
- Calcium-binding EF hand family protein
- Peptidyl-prolyl cis-trans isomerase CYP38, chloroplastic
- MLO-like protein 1
Sequence:
MSASCALTPSVRTELFSSSSSKRSIFPARICRPRNKCEISRRDFAIRGGIVASGVSVMDTSSASSQSVQGSERLAFKPEGYNFWEWRGHKIHYVVQGEGSPLVLIHGFGASVFHWRYNIPELAKKYKVYALDLLGFGWSDKALIEYDAMVWTDQVIDFMKEVVKEPAVVVGNSLGGFTALSVAVGLPEQVTGVALLNSAGQFAAESRKREEADETVITKFIVKPLKEIFQRVVLGFLFWQAKQPSRIESVLKSVYIDSTNVDDYLVESISKPATDPNAGEVYYRLMTRFLTNQSRYTLDSVLSKMTCPLLLVWGDLDPWVGPAKAEKIKAFYSNSSLVHLQAGHCPHDEVPEAVNKALLDWLSINIASKPASPIVLET
Protein: Aminopeptidase N (EC 3.4.11.2) (Q5E5B9)
Organism: Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
Interaction partners:
- Probable cytosol aminopeptidase
- Aminopeptidase B
- Cytosol non-specific dipeptidase
- Glutathione synthetase
- Glutathione hydrolase proenzyme
- Glutamate--cysteine ligase
- Glutamate--cysteine ligase
- Cysteine synthase
- glutathione synthase
- Serine hydroxymethyltransferase
Sequence:
MSQQPQAKFRSDYQSPEFIISDIDLVFDLNDTNTLVSATSKVQQLKQSTDLLLEGEGMKLVSLKIDDVEYSDFTQTDTQLTIHNVSGDFTLTIITEINPQENTALEGLYKSGDGFCTQCEAEGFRRITYYLDRPDVLARFTTKVIADKEAYPHLLSNGNRISQGDLDGGKHFVHWQDPFPKPAYLFALVAGNFDVLTDTYKTKSGRDVALEIYVDQGNLDRTPHAMTSLINSMKWDEERFDLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKFVLAKQETATDTDYLGIEAVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRSVNRINNVRIMRGPQFAEDASPMAHPIRPEKVIEMNNFYTLTVYEKGSEVIRMMHTLLGEANFQKGMKLYFERHDGTAATCEDFVLAMENASGIDLTQFRRWYSQSGTPVLTVSSSYDDAKNEYALTVKQHTPATEDQTDKLPLHIPFDIELYAQDGLVIQLRCNNEKVSNVLNVTEEEQTFIFEQVSEKPVVSLLREFSAPVKLNYAYSDEELIFLMVHAQNDFARWDAGQMLLANYIRKNIANIQDDKELVLPQSVVDAFRGVLLNAELEHAFIAEMFVLPNHNEITGWFDTVDVDAIDKALGFIKQTLATELKDEFSATYHSLKQGSYSVEHDAIGKRALRNCSLSYLAKTEIGEALVEAQYQDADNMTDTMAAMGAANAAELSIRQTLMNDFSAKWSHDGLVMDKWFILQGSNPSSEALSIIKETMNHKAFSLKNPNRTRSLIGSFAGGNAVNFHSKTGEGYAFLGDILIEMNESNPQVASRLVDPLLKFKKYDSDRQSLIKAQLQRLADLDNLAKDLYEKVTKALA
Protein: Possible oxidoreductase (O06538)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Conserved hypothetical membrane protein
- Uncharacterized protein
- Polyketide synthase-like Pks10
- Methyl-branched alkylpyrone synthesis polyketide synthase-like Pks11
- Anti-sigma-L factor RslA
- Electron transfer flavoprotein subunit beta
- Alpha-pyrone synthesis polyketide synthase-like Pks18
Sequence:
MTSYDTDLLVVGGGPGGLATALHARARGLSVIVAEPRENPIDKACGEGLMPGGLAELTSLGVDPVGLPFHGIAYVGEHRRVQARFRTGPGRGVRRTTLHAALAARAKEQDTEWIRSRVATIQQDAHGVTAAGVRAKWLVAADGLHSAVRRAVGIKATAGTPRRYGVRWHYRLPVWSDFVEVHWSRWGEAYVTPVEPDLVGVAILSRQRPELAWFPSLAHHLQDASRGHARGCGPLRQVVSRRVAGRVLLVGDAAGYEDALTGEGISLAVKQAAAAVSAIVDDTPASYEAAWHRITRDYRLVTRGLVLASTPRAARRAIVPLCALLPTAFRYGVNILAY
Protein: Uncharacterized protein (Q384L5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Large ribosomal subunit protein uL3m
- Rhodanese domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- 50S ribosomal protein L17, putative
- Mitochondrial RNA binding complex 1 subunit
- 50S ribosomal protein L16, putative
- AB hydrolase-1 domain-containing protein
Sequence:
MLNPTFSLYRKTLQSYPVPPKIRHYDRRWSGSRTNPYNRQYWRVIMNENYSRPSFWVSDFRHRYLMRTGTDYQGQVPSSPQPGLYQGFSDVHKLLANHPKPQRESRHLPVLPMTPRVVFEHANEKRIDTAKKMRRDRRRIEELKTLEFWGWYMKLQRVRGRWCREQGVSSRGVYGPAVDAAELWG