wanglab/gogpt-training-data huggingface dataset:
Protein: Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) (Q64716)
Organism: Rattus norvegicus (Rat)
Function: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Insulin-2
- Insulin-1
- Insulin receptor
- Growth factor receptor-bound protein 2
- Insulin-like growth factor 1
- SOS Ras/Rho guanine nucleotide exchange factor 2
- SOS Ras/Rac guanine nucleotide exchange factor 1
- Insulin-like growth factor 1 receptor
- Insulin receptor substrate 1
- Tyrosine-protein phosphatase non-receptor type 1
Sequence:
MAVPALWPWGVYLLMSLLSLGSCLDTLEVCPSLDIRSEVTELRRLENCSVVEGHLQILLMFAATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGARLFLGYALIIFEMPHLRDIGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCVRTTFGGHTDYRCWTSSHCQRVCPCPRGLACTVGGECCHSECLGGCSQPEDPRACVACRHLYFQGVCLPTCPPGTYQYESWRCVTAELCGHLREVPGHATAFGIYEGSCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGSLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVTLGFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAACQTRTLRFVFNLTEEDRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPVQRNGNITYYLVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDREDPALEAEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQRDSERHRRETGLLRLGKNNSDFEIHEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVVWKAVGKSSVILHWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKVGGVHLALLPPGNYSAKVRATSLAGNGSWTDGVAFYITGPEEEDTGGLRILLTVTPVGFMLLVMLAALGFFYSKKRNSTLYTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHILDRIQDELRPSFRLCSFYYSPECQRGQASLLPTEAEPDSPPTLNGASDYGPPNGDPGH
Protein: Galectin (Q94215)
Organism: Caenorhabditis elegans
Interaction partners:
- C-type lectin domain-containing protein
- C-type lectin domain-containing protein
- C-type lectin domain-containing protein
- C-type lectin domain-containing protein
- C-type lectin domain-containing protein
- C-type LECtin
- CUB-like domain-containing protein
- Alpha-mannosidase
- Galectin
- C-type lectin domain-containing protein
Sequence:
MVHVIENPPIPLTTPIYEGMREHSSVEIHGEVFQGPQGGFTVEFPTKNGVALHISVRMGSYGQNVIVFNHLQRGRWHREEHHQNTIMFGRPFCMRIHNEHRKYSIHVDGHHIGHYHHHKCPKRIVAMTVRGDLRVGKIHFENFKHHNGGGTEIGVMQMPVAPTPIVVAQPPPPMIVPQPQIVPVVQQIMQPMVQPIYPSVQPIVYPTATPIIYTQPEVIYMDGYHHHRHHHY
Protein: Ion transport protein (A8EVM5)
Organism: Aliarcobacter butzleri (strain RM4018) (Arcobacter butzleri)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MYLRITNIVESSFFTKFIIYLIVLNGITMGLETSKTFMQSFGVYTTLFNQIVITIFTIEIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRVLRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAIIVDAMAILNQKEEQHIIDEVQSHEDNINNEIIKLREEIVELKELIKTSLKN
Protein: Iroquois homeobox protein ziro1-a (Q8JH33)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MSFPQLGYPQYLSASQAVYGGDRPGVLTPSSRAGSAEIGGSASAAAAAVSSVLGMYPYAHNYSAFLPYTSADLALFSQMGSQYDLKDSPGVHPASFAAHTSPAFYPYGQFQYGDPARPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDDENIFGSDNEGDAEKNEDEEEIDLESIDIDKIDDNDGDQSNEEDEDKRAELESLQEKRHASKEPSDGNNNTTRVLSPGRQGGFQVPVSNKPKIWSLAETATSPDSAQKPTSPSVPVSHPAFLPSHGLYTCQIGKFHNWTNGAFLGQNSLLNVRSFLGVNQHNHPAQQQQQQTGPASLQVLSAGNTDKMPEDLSPKHIAPETSRNQHRGSSQRCPPLDQHICTPKRTDGTNNGH
Protein: Uncharacterized protein YkgG (P77433)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized electron transport protein YkgF
- Uncharacterized protein YkgE
- Phosphate acetyltransferase
Sequence:
MDNRGEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLNQQQRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISERLQQECNAVVWDPAKGAENISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLPEYSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVHGPVKAVYLIIEDC
Protein: Probable LRR receptor-like serine/threonine-protein kinase At1g56140 (EC 2.7.11.1) (C0LGH3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized protein At3g52710
- AT4g30240/F9N11_90
- DNA-directed RNA polymerase II subunit 7
- DnaJ heat shock amino-terminal domain protein
Sequence:
MLRLWRYLCLLLTVWFLCNFGPVYVVRAQNRTGATTHPDEALALNSIFAAWRIRAPREWNISGELCSGAAIDASVLDSNPAYNPLIKCDCSFENSTICRITNIKVYAMEVVGSIPQQLWTLEYLTNLNLGQNVLTGSLPPALGNLTRMRWMTFGINALSGPIPKEIGLLTDLRLLSISSNNFSGSIPDEIGRCTKLQQIYIDSSGLSGGLPVSFANLVELEQAWIADMELTGQIPDFIGDWTKLTTLRILGTGLSGPIPASFSNLTSLTELRLGDISNGNSSLEFIKDMKSLSILVLRNNNLTGTIPSNIGEYSSLRQLDLSFNKLHGTIPASLFNLRQLTHLFLGNNTLNGSLPTQKGQSLSNVDVSYNDLSGSLPSWVSLPNLNLNLVANNFTLEGLDNRVLSGLNCLQKNFPCNRGKGIYSDFSINCGGPEIRSVTEAVFEREDEDLGPASFVVSAGQRWAASSVGLFAGSSNNIYISTSQSQFVNTLDSELFQSARLSASSLRYYGLGLENGGYTVTLQFAEIQILGSTSNTWRGLGRRRFDIYVQGRLVEKDFDVRRTAGDSTVRAVQREYKANVSQNHLEIHLFWAGKGTCCIPIQGAYGPLISAVGATPDFTPTVGNRPPSKGKSMTGTIVGVIVGVGLLSIISGVVIFIIRKRRKRYTDDEEILSMDVKPYTFTYSELKSATQDFDPSNKLGEGGFGPVYKGKLNDGREVAVKLLSVGSRQGKGQFVAEIVAISAVQHRNLVKLYGCCYEGEHRLLVYEYLPNGSLDQALFGEKTLHLDWSTRYEICLGVARGLVYLHEEARLRIVHRDVKASNILLDSKLVPKVSDFGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRGHLTEKTDVYAFGVVALELVSGRPNSDENLEDEKRYLLEWAWNLHEKGREVELIDHQLTEFNMEEGKRMIGIALLCTQTSHALRPPMSRVVAMLSGDVEVSDVTSKPGYLTDWRFDDTTASSISGFPLRNTQASESFTSFVAPRSEISPRNNDARPMLGAQMNEGR
Protein: Glutathione exchanger 2 (P36173)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Proton/glutathione antiporter that imports glutathione from the vacuole and exports it through the plasma membrane. Involved in resistance to oxidative stress and modulation of the PKA pathway.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21490148}; Multi-pass membrane protein {ECO:0000269|PubMed:21490148}. Vacuole membrane {ECO:0000269|PubMed:21490148}; Multi-pass membrane protein {ECO:0000269|PubMed:21490148}.
Interaction partners:
Sequence:
MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSTLPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLLVAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFTFTMFMRNPELIDKATHEEFTEDGLVVLPDEENIFSQIKALFRHNRSNKKSGC
Protein: DNA dC->dU-editing enzyme APOBEC-3 (EC 3.5.4.38) (Apolipoprotein B mRNA-editing complex 3) (Arp3) (CEM-15) (CEM15) (Q99J72)
Organism: Mus musculus (Mouse)
Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity against HIV-1, simian immunodeficiency viruses (SIVs), mouse mammary tumor virus (MMTV) and friend murine leukemia virus (FrMLV) and may inhibit the mobility of LTR retrotransposons.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16527742}.
Interaction partners:
- Cullin-5
- Elongin-B
- Elongin-C
- RING-box protein 2
- Putative C->U-editing enzyme APOBEC-4
- Core-binding factor subunit beta
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome b-c1 complex subunit 7
Sequence:
MQPQRLGPRAGMGPFCLGCSHRKCYSPIRNLISQETFKFHFKNLGYAKGRKDTFLCYEVTRKDCDSPVSLHHGVFKNKDNIHAEICFLYWFHDKVLKVLSPREEFKITWYMSWSPCFECAEQIVRFLATHHNLSLDIFSSRLYNVQDPETQQNLCRLVQEGAQVAAMDLYEFKKCWKKFVDNGGRRFRPWKRLLTNFRYQDSKLQEILRPCYISVPSSSSSTLSNICLTKGLPETRFWVEGRRMDPLSEEEFYSQFYNQRVKHLCYYHRMKPYLCYQLEQFNGQAPLKGCLLSEKGKQHAEILFLDKIRSMELSQVTITCYLTWSPCPNCAWQLAAFKRDRPDLILHIYTSRLYFHWKRPFQKGLCSLWQSGILVDVMDLPQFTDCWTNFVNPKRPFWPWKGLEIISRRTQRRLRRIKESWGLQDLVNDFGNLQLGPPMS
Protein: Clathrin heavy chain (C0MHR2)
Organism: Sus scrofa (Pig)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|PIRNR:PIRNR002290}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR002290}; Cytoplasmic side {ECO:0000256|PIRNR:PIRNR002290}. Membrane, coated pit {ECO:0000256|PIRNR:PIRNR002290}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR002290}; Cytoplasmic side {ECO:0000256|PIRNR:PIRNR002290}.
Interaction partners:
Sequence:
MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEEPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM
Protein: Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3) (Q9NT99)
Organism: Homo sapiens (Human)
Function: Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner (By similarity).
Subcellular location: Membrane; Single-pass membrane protein. Presynaptic cell membrane {ECO:0000250}.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase S
- Receptor-type tyrosine-protein phosphatase F
- Netrin-G1
- Netrin-G2
- Receptor-type tyrosine-protein phosphatase delta
- Interleukin-1 receptor accessory protein-like 1
- Disks large homolog 4
Sequence:
MARARGSPCPPLPPGRMSWPHGALLFLWLFSPPLGAGGGGVAVTSAAGGGSPPATSCPVACSCSNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGTGSGGGGPGGSGGVGGGSGGYTYFTTVTVETLETQPGEEALQPRGTEKEPPGPTTDGVWGGGRPGDAAGPASSSTTAPAPRSSRPTEKAFTVPITDVTENALKDLDDVMKTTKIIIGCFVAITFMAAVMLVAFYKLRKQHQLHKHHGPTRTVEIINVEDELPAASAVSVAAAAAVASGGGVGGDSHLALPALERDHLNHHHYVAAAFKAHYSSNPSGGGCGGKGPPGLNSIHEPLLFKSGSKENVQETQI
Protein: DNA replication licensing factor mcm3 (EC 3.6.4.12) (Minichromosome maintenance protein 3) (P30666)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- DNA replication complex GINS protein sld5
- DNA replication complex GINS protein psf2
- Cell division cycle protein cdt1
- DNA replication licensing factor mcm2
- DNA replication licensing factor mcm6
- DNA replication licensing factor mcm4
- DNA replication licensing factor mcm5
- Cell division control protein 45 homolog
- DNA replication licensing factor mcm7
- Origin recognition complex subunit 2
Sequence:
MTELLADEVFKDRVRIFQEYLEHDTDDANVTLYQEAILRMLNMGQRRLIVNIDELRDYNRELADGVLLKPLEYVEPFDEALRNVVSTLIDPVVHKDLKDKLFYVGFRGSFGDHHVNPRTLRAMHLNKMISLEGIVTRCSFVRPKVIKSVHYCEATKRHHFKQYADATMNGGLSFQSTVYPTQDENGNPLSIEFGFSTFRDHQSISLQEMPERAPPGQLPRSIDILLDDDLVDTVKPGDRVNIVGQYRSMGSKTSGNTSATFRTVLLANNVVLLGNKPGLGNVGGGALDITDADIRNINKLARKKNVFELLSTSLAPSIYGYEYVKQAILLLLLGGTEKNLTNGTHIRGDINILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPIYGQYDIRKDPHQNIALPDSMLSRFDLLFIVTDDIDDKKDRALSEHVLRMHRYLPPGVEPGTPVRDSLNSVLNVGATNAAGVSTENVEQEVETPVWETFSSLLHANARTKKKELLNINFVRKYIQYAKSRIHPILNQATAEYITNIYCGLRNDDLQGNQRRTSPLTARTLETLIRLSTAHAKARLSSVVEVKDAKAAEKILRYALFREVVKPKRKKHKKQRLEAGEEFDSEDDNSDDMDIEESEEEMDTNMVIDSGSRRVTRSQNATSQSQESGSEIGSSIAGTAGSYNVGTSNTQLSWPSTHSTLPATSRELASSDRNINTGTSVASEVSASVSEQSTVSLPREKMSVFMARLASLTKSELFSEECASLEDVLESINNIEDDVGFSREEAIVALKEMDAQNKIMFSDNVVYRI
Protein: Glia maturation factor beta (GMF-beta) (P60983)
Organism: Homo sapiens (Human)
Function: This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
Interaction partners:
Sequence:
MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH
Protein: Probable pectin lyase D (PLD) (EC 4.2.2.10) (A2RBL2)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Function: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MKYAAALTAVAALAARAAAVGVSGTPVGFASSATGGGDATPVYPTTTDELVSYLGDDEARVIVLSKTFDFTDTEGTTTTTGCAPWGTASGCQLAINKDDWCTNYEPDAPTTTVTYNTAGELGITVNSNKSLIGEGTSGVIKGRGLRMVSGVSNIIIQNIAVTDINPEYVWGGDAITLDEADLVWIDHVTTARIGRQHYVLGTDADSRVSITNNYINGESDYSATCDGHHYWNVYLDGSSDKVTFSGNYLYKTSGRAPKVQDNTYLHIYNNYWENNSGHAFEIGSGGYVLAEGNYFSNVDTVLETDTFEGALFSSDSASSTCESYIGRSCVANVNGGDLTGTSTTVLSNLSGDTLPSADAASTSPASNAGQGNL
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (A8WGA9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MATPTSLDPELVREVLECPICLETYNQDQLRPKLLQCGHSVCRQCLEKLLASTINGVRCPFCSKVSRMSSISQLADNLTVLKIIDCASACSSNMGLMCKSCKNRLPRQYCCDCSIVLCDICKNEGHQRQGHVVQAIRMAAELRRKDIGAKLSDLREAMGNIQKKKAAIDNVTKSLRMKYKAVQQEYAKAELRLQEELGRSRRAFAASLAEIEKLNAQILEEQTYLLNIAEVQVVSRCDYLTMRIKQTDIALLEEGSNNDEEEDLDLKTNLPVVLKLQDPELVKIENSKSLEVGQLTTKPCNVNVEEEEDGLDFPTATSAPLDIYRDIDMVPAVEEAVCASPGSFKSKSVDGGGPSPGASGGQLCQFVKKMGCKGNLPGMFNLPVSICVTLQGEVLVADRGNYRIQIFNRKGFQREIRRNPSSIDNFVLSFLGADLPNLIPLSIAITAQGLIGVTDNYDNSVKVYTTDGHCIACHKNQLIKPWGIAAMPSGQFVVSDVEGGKLWCLAVDRNVGVVNYNRLCSAVRPKFVTCDSSGTVYFTQGLGLNIENRHNEHHLEGGFSIGSVGMDGQLGKQLSHFFSETEDFRCITGMCVDSNGDLIVTDSGRKEILQFPKEGGYNILIQEGLTCPVGVAVTQKGQLLVLDCWDHCVKVYTYLQRRRSSTC
Protein: BTB (POZ) domain containing 10 (Q5EAP0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQHHIEREKDHSSSRPSSPRPQRASPNGSISSAGNSSRNSSQSSSDGSCKASGEMVFVYENAKEGARSVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDSLPSHPASGNNDLDPDAQNPML
Protein: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2) (P50583)
Organism: Homo sapiens (Human)
Function: Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (By similarity). Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (By similarity).
Interaction partners:
- Inosine triphosphate pyrophosphatase
- Nucleoside diphosphate kinase 6
- CTP synthase 1
- CTP synthase 2
- Nucleoside diphosphate kinase 3
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- Nucleoside diphosphate kinase B
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
- Adenylate cyclase type 9
- Nucleoside diphosphate kinase A
Sequence:
MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA
Protein: Large ribosomal subunit protein bL9m (54S ribosomal protein L50, mitochondrial) (P53724)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16823961}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein bL19m
- Small ribosomal subunit protein uS8m
- Large ribosomal subunit protein mL43
- Small ribosomal subunit protein uS2m
- Large ribosomal subunit protein bL31m
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein bL36m
- Small ribosomal subunit protein uS17m
- Small ribosomal subunit protein mS41
- Large ribosomal subunit protein uL22m
Sequence:
MLHCTQVCLSALTKRTHRVKVQVLKDFPRFQLYKGQVANVKPSLMRNYLHNFNGAKYILSEEHDINTELLKQYQTLEAKLEEDHQQLSKRHETEVQKNMELRKESVFGHKKEEKPKEEKKGLLDSGITIEEVKIPGLDI
Protein: Mitochondrial import receptor subunit TOM5 homolog (Q5R676)
Organism: Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Subcellular location: Mitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Mitochondrial import receptor subunit TOM7 homolog
- Translocase of outer mitochondrial membrane 40 like.
- Translocase of outer mitochondrial membrane 22.
- TOMM40 isoform 2
- TOMM40 isoform 6
- Mitochondrial import receptor subunit TOM20 homolog
- TOMM20L isoform 1.
- Mitochondrial import receptor subunit TOM70
Sequence:
MFRIEGLAPKLDPEEMKRKMREDVISSIRNFLIYVALLRVTPFILKKLDSI
Protein: WUSCHEL-related homeobox 1 (PFS2-like protein) (Q6X7K0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor which may be involved in developmental processes.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Protein ASYMMETRIC LEAVES 2
- Transcription repressor KAN1
- Probable transcription factor KAN2
- Axial regulator YABBY 1
- Axial regulator YABBY 3
- Transcription factor AS1
- Probable transcription factor KAN3
- Axial regulator YABBY 5
- Auxin response factor 4
- Ethylene-responsive transcription factor ESR2
Sequence:
MWTMGYNEGGADSFNGGRKLRPLIPRLTSCPTAAVNTNSDHRFNMAVVTMTAEQNKRELMMLNSEPQHPPVMVSSRWNPTPDQLRVLEELYRQGTRTPSADHIQQITAQLRRYGKIEGKNVFYWFQNHKARERQKRRRQMETGHEETVLSTASLVSNHGFDKKDPPGYKVEQVKNWICSVGCDTQPEKPSRDYHLEEPANIRVEHNARCGGDERRSFLGINTTWQMMQLPPSFYSSSHHHHQRNLILNSPTVSSNMSNSNNAVSASKDTVTVSPVFLRTREATNTETCHRNGDDNKDQEQHEDCSNGELDHQEQTLELFPLRKEGFCSDGEKDKNISGIHCFYEFLPLKN
Protein: Uncharacterized protein C2H8.04 (Q9Y7R1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MSAAWRKKITNAHRNECLQVYRSLLRSCDEIQNRPLGEKLSKIVKARTRHYQNVGNAYKAEALLKDAKKQCETLKSALNGKLPEVNIESHMLSKYRKYLNEGGKQGDVGITKPHTKTKKLKSNSIFNYVRNGEVLYHLVSTTGGDTFLRPKFWPQSQRISGMLKKRITMKENKHRLIQSMSCMLRHAKLEDEFMKAYISEEDVGYADEIHKCIQMVLSDLDSIYKRESKNWHIVSQFYNMLELEAARQKLENRYLNFWKVSRRSSP
Protein: Large ribosomal subunit protein uL29 (60S ribosomal protein L35) (Q29361)
Organism: Sus scrofa (Pig)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P42766}.
Interaction partners:
- Large ribosomal subunit protein eL34
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL30
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein eL38
- Ribosomal protein L24.
- Large ribosomal subunit protein uL18
Sequence:
MAKIKARDLRGKKKEELLKQLEDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKFAVKA
Protein: Dynein regulatory complex subunit 2 (Coiled-coil domain-containing protein 65 homolog) (Flagellar-associated protein 250) (A8JB22)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular location: Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000269|PubMed:29167384}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:29167384}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:23427265, ECO:0000269|PubMed:25411337}.
Interaction partners:
Sequence:
MVKAGKKVKGASKVRENETEEEKKIRLEMEALAADEAERKAQEAARVALRERQLREQRYAHLNGIKIHNQWRKIMRMAKVEELRREIEILSQNHEREVDRKDAIMQMLDRDLEEAEEQYSLAVRSHMLVVDNLLDLQYQRMRALEAEFAADLKALEDEFETERTEIVNAHTRQRKDMGDMIAAMEGEFADAEAELRQEYEAQREEIKNRNSEEYNVLKIQLEGIIEELEKSFELAHRAYLESTEHRTNTFRTLTKDDAKAALKIERQMRKLVRLQEALQHWRTKIATNGREWEERNRALRNEKEIMARHYAKLKSSMDAFRAGQAERLKQLSLASSGAMETLRGKLAVAENVLKLAELARKYETEQEKVLPFWNPAQAVPSGEQGDEEAAAQAEAEAAALEPSAAELGELGLRASMPEDSSKEAPGPSKSSAGPGKPKFSSYGLDPSSGSEVDEWDYLNCFFRRYNKALLDKTAIDKEKSRLERENADLRSILKQYLDGISVNDDVLNNPVNPLLVVNNRLQITLTERNKARAAAMAQRAAAATGAGLSVTGQGAGGGGQKQLVEVQVVSRVS