wanglab/gogpt-training-data huggingface dataset:
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (D3ZUV2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- NHS actin remodeling regulator
- Protein jagged-1
Sequence:
MSNSRNNRVMVEGVGARVVRGPDWKWGKQDGGEGHVGTVRSFESPEEVVVVWDNGTAANYRCSGAYDLRILDSAPTGIKHDGTMCDTCRQQPIIGIRWKCAECTNYDLCTVCYHGDKHHLRHRFYRITTPGSERVLLESRRKSKKITARGIFAGARVVRGVDWQWEDQDGGNGRRGKVTEIQDWSASSPHSAAYVLWDNGAKNLYRVGFEGMSDLKCVQDAKGGSFYRDHCPVLGEQNGNRNPGGLQIGDLVNIDLDLEIVQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVAPAGSTISNASGERLSQLLKKLFETQESGDLNEELVKAAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPSLCKALAKCHKEKVSGQVGSRSPSMISNDSETLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKIEECVVCSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERRVPFITCCGGKSSEEPSDDISSGNIPVLQKDKDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFLCGHGTCQLCGDRMSECPICRKAIERRILLY
Protein: Multimerin-1 (B2RPV6)
Organism: Mus musculus (Mouse)
Function: Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q13201}. Note=O-fucosylation of Thr-201 and Thr-1037 is important for protein secretion. {ECO:0000250|UniProtKB:Q13201}.
Interaction partners:
- Vitronectin
- Urokinase-type plasminogen activator
- EMILIN-1
- Urokinase plasminogen activator surface receptor
- Multimerin-2
Sequence:
MLGLKFLVLLSILWGRVFRLTNTQHSWTAPKDEDASLTPNHASASVSEILSLQVLSATQNPSTQGPAAAERSSEDDVLLQSTSQPSETSTPPEGRHQTPLEKTGTAVVSLPLSLQDKPSIKPSTGAGTVMLANATLKFLQSFSRKSDQQEVSTKSAGDMGNRSARETHLRRSDNSRNQRPSYQKPSFETTRGKNWCAHVHTKLSPTVILDTGSHLPSGRGSCGWYSSGLCSRRSQKTSNAVYRMQHKIVTSLEWRCCPGYIGPNCQLKVEEQQQLAHSNQAESHTAVDQGRAQQQKQDCGDPAMIQKLAEQLSQQERKLSLLQKKVDNASLVADDMRNAYLSLEGKVGEDNSRQFQSFLKALKSKSIEDLLKNIVKEQFKVFQDDMQETTAQIFKTVSSLSEDLESTRQAVLQVNQSFVSSTAQKDFAFMQENQPTWKDITDLKNSIMNIRQEMALTCEKPVKELEAKQAHLEGALRQEHSQIVLYHQSLNETLSKMQEAHIQLLSVLQVSGTENVATEESLNSNVTKYISVLQETASKQGLMLLQMLSDLHVQESKISNLTILLEMEKESARGECEEMLSKCRHDFKFQLKDTEENLHVLNQTLSEVIFPMDIKVDKMSEQLNDLTYDMEILQPLLEQRSSLQHQVIHKPKEATVTRRELQNLIGAINQLNVLTKELTKRHNLLRNEVQSRGEAFERRISEHALETEDGLNKTMTVINNAIDFVQDNYVLKETLSAMTYNPKVCECNQNMDNILTFVSEFQHLNDSIQTLVNNKEKYNFILQIAKALTAIPKDEKLNQLNFQNIYQLFNETTSQVNKCQQNMSHLEENMLSVTKTAKEFETRLQGIESKVTKTLIPYYISFKKGGILSNERDVDLQLKVLNTRFKALEAKSIHLSVSFSLLNKTVRELSMACRNASTGTCGQNALIPRWTKGSLPGSQSSQKSLTELVESIVEIKTQAALSNLTWNVDRLLSDTLANIVKPQKQIKLQKKPNTLKKTVNMTTILIGRTQRNTDTIIHPVAQEHSSCSSFPCQNGGTCISGRSNFICACRHPFMGDTCTVKIKEDDAVAPDFSKGSYRYAPMVAFFVSHTHGMTAPGPILFNDLSVNYGASYNPRTGKFRIPYLGVYIFKYTIESFSAHISGFFVVDGVDKLRFESENADNEIHCDRVLTGDALFELNYGQEVWLRLVKGTIPIKYPPVTTFSGYLLYRT
Protein: GTPase-activating protein rrc-1 (RhoGAP for Rac-1 and Cdc-42) (Q20498)
Organism: Caenorhabditis elegans
Function: Functions as a GTPase-activating protein (GAP) for ced-10/rac-1 and CDC42.
Interaction partners:
Sequence:
MEGIEESFAPLSPKSPFARRNGRSLRIQRLVDCQHFHYSSVELGPVRVAIIAINADENATERIKMRVESESNSWLVERSREDWAVFDRQLHRCVFERRHSRLDELFPLIHLETAKFEEVLVKYTERLSELTGSIITCYPVLKFLEIDSRGGHFEPAEETSINVPAIAAAVVTKDFEPTESSQLRLRVGDIVSITEMSTASPSEQTFWKAKLTISNQKIVDPQNARLGFEIGYFPRDCVMLIDDKRLPNPLNNEQKASTRNARRYMTTMFRNRRREPIFGLELTDLYMRTGKKVPVIVEKCCASIEDQGIVTGIYRQCGIQSNIQRLRAKFDSGAEPDLHEFGQRDIYSVSSLLKQYFRQLPNPLFTYQAYPKLIEAFEKEDSLSEKVESLRFSLETMPEAHYRTAKFLMEHLTRLCKSKSLTDMTSKNLAIVWSPNLFRPPPTLNGADTHLLSGLNVHTAICDFFIENSESLFVNDIDEEQSKCTSVENSFTTISKSATMSDMRSESESKWPRFFRGKSVEGFWKFNRKQQTSTGELCGSPTSEVKWRSRSTRSHSTDAAFQSSRTDSFIQLMHTGMDQIREGMRIFRARARSMRPTSRPPPSPRTRRARFSNGSSNNVQKLNESDIQHEIPLATTEPSITPEPKNTVDPHQIMTRTISVNDSDDQSFEENGLREMRERKVMFKAATQEHVATFHERSSPVEEWSSDSRESLHLEMSRYDNVSPSGTITRNQREPITNLSPAAQMLFFESSRASHLFSA
Protein: Gibberellin-regulated protein 5 (GAST1 protein homolog 5) (Q84J95)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Gibberellin-regulated protein that acts as a negative regulator of gibberellin-induced flowering and stem growth. May inhibit flowering and inflorescence growth via a pathway involving GAI and by enhancing FLC expression and repressing FT and LFY. Acts as a negative regulator in thermotolerance by resogulating both salicylic acid (SA) signaling and heat shock-protein accumulation.
Subcellular location: Secreted {ECO:0000269|PubMed:19190987}. Secreted, cell wall {ECO:0000269|PubMed:19190987}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:19190987}.
Interaction partners:
- ASI1-immunoprecipitated protein 2
- LOB domain-containing protein 22
- CMP-sialic acid transporter 2
Sequence:
MANCIRRNALFFLTLLFLLSVSNLVQAARGGGKLKPQQCNSKCSFRCSATSHKKPCMFFCLKCCKKCLCVPPGTFGNKQTCPCYNNWKTKEGRPKCP
Protein: Tetraspanin-1 (P34285)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- TetraSPanin family
- Zinc metalloproteinase nas-33
- C6 domain-containing protein
Sequence:
MATWKFIIRSVLFFLDLAMLLAALALIAVGFWMGYDSSFDTDLKNVIYKYDDPKSLADAKFNIRVWLIVVFWSIIGLSLGAVVTAVLGMISSVWPKRKGFMITYLVLIIVLVSLEIGCGVAVLVRRNSLHDNTNSLIDAMYTTNSVNDLKIIQDKYNCCGIENSLFNVMYCGPMSQKPHCDVAVFDSVDNTMMISGIILLVILILQTIAIILPVPILISRKKTYKYSYEPRVTQLADITEDTRF
Protein: Bruno 3, isoform F (M9MSL1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVHIIELVGQPKVEFAQQVTMNRALQLKPAENESRSGCAFVKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRMQQMAGHMNLLNPFVFNQFSPYGAYAQQQQQAALMAAAATAPGSAAAYMNPMAALATQIPHGLNGTGQPPSLPSPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVFTNGIPQTAFPGHPLHLTIPPQGLPNGDAATLQHAFPGLPPFPGVDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPY
Protein: Coiled-coil domain-containing protein 33 (Speriolin-binding factor) (Q3ULW6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAFRGPDPYLPASLLSQRLKAGEKTLDLEFEILSVGFNEEGRYALRLSAENPLQAGSSAGVQLQVNDGDPLPACSAVTEVIEQQDPGQSLTFTRNKFIFTLPKGFCKNDGQSDAHLRVEALRLDGSSGQEAQRVGEAIFPIYPRPDEPRMNLTAQDHEDLYRYCGNLALLRASEDPTARHCGGLAYSVAFHVHRDPRSSVSDCQLEPSQPELQTSREALSDKIEESYMSPFSTDSDQEGLSWEAGPWQHPAQVPEEPQGRLDTSQDPYPAANYLAPCNKETITVTLYGATNLPAGKDGSEPWPYVVVKTTSEKANKHSPQAMTSVTSEPTRAPVWGDTVNVEIQAEDTGREDLILKVMDNKRKKELVSYDIPIKYLRIFHPYQFKLEKVFLRGVNEPLVNSLKPMVVIARVVPNYTEFKARQARRDPASVGLPLTQVSFPISSPMNFDVPRINQNGYPQLSKPGGPPEQPLWNQSFLFQARDGATSFSENTALVLEYYPSASMQSSEPWALNQPLGVSVLPLKSRLYHKMLTGKHLQGLQVERLPIMRPENFLTPNNSKALPTINPKILDENLGAIRESWSMSSLDSAQEVEELQPRDVEMNNYRRAMQKMAEDILALKKQANILEEENGMLRSHLSQQSIEEQSRAEEENLAVSMKQKLLLNELDMKRLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAAQLRRYQDKLQKMKALEDTVRHQEKVIEKMEQILEERLCERKEPIPSNRPQGKPIMASGIPLGPMGETLAVDLYSMLLAENTRLRTELEKNRQQSAPIILQQQALPVDPRELGAGGDLAERLQDTNGPGHPKSTETLPAQVGVPGGYSTAQAAPGAPAVHKPKINIWSSGGMRTQDFLGGTSDKFNLLAKLEQAQSRILSLENQLEESARHWAREKQNLAIRLQEQQHGFGQPPNSIIIDQPNAGASKNPQQLSKLEPSLPSSDKKLNRPSDSQIEISNNQKT
Protein: Protein PIGBOS1 (PIGB opposite strand protein 1) (A0A0B4J2F0)
Organism: Homo sapiens (Human)
Function: Plays a role in regulation of the unfolded protein response triggered by endoplasmic reticulum (ER) stress resulting from the presence of unfolded proteins in the ER lumen.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:31653868}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MFRRLTFAQLLFATVLGIAGGVYIFQPVFEQYAKDQKELKEKMQLVQESEEKKS
Protein: Uncharacterized protein (Q54WC4)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MSSQEQQKSKQNQAQEGVDGVWLDKYSTLSRVYNYGFVNGSIEKGKEWYNYIKDSNSYVKSTLEFGENGVVAVGRPLLDKLEQYDVIVKKVDEYGNTGLDILEKKVESIKETGENLANKADSAADGLISVSANYTPNAVIGLVQKTNNMIDSLIDSLLPPKDDDQVNEMSDEEKFQLEKRMKFLLKLRKRLNTQSILEIPSNSIHLVTGYSGKSYSQAMDNISQLSNSISKITVNSQFSKVFIDQIYHYTDILVGQVAAVSVWFREINISETLISLGELSKMINESKNQVLELSDPQEKVDKLKKDLSKILKSCLDVLHNQMEGGKDKLESFKESVSDHQYFVASFSLLESSLNKLSVTLKNYLDNLEEKSSSSSNDNSTN
Protein: Large ribosomal subunit protein uL14m (60S ribosomal protein L14, mitochondrial) (O21033)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q6P1L8}.
Interaction partners:
- Small ribosomal subunit protein eS30
- Small ribosomal subunit protein eS24
- Uncharacterized protein
- Large ribosomal subunit protein uL6m
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein uS8
- Small ribosomal subunit protein uS13
Sequence:
MIIKGSNFSVMDNSGARKVQCIQTLEGKKPTSLLRVGDKIVVVIKKMEKRKGGKYKLKVKKSDVCYAVIVKSKQPVRRKSGIIVNAGENGVILLTKTKEPIGTRLTGVVFKEVQRTGLLKNVSISKYII
Protein: Transmembrane protein 164 (Arachidonoyl ether phospholipid synthase) (Q5U3C3)
Organism: Homo sapiens (Human)
Function: Positive regulator of ferroptosis. Selectively mediates ATG5-dependent autophagosome formation during ferroptosis, rather than during starvation, and regulates the degradation of ferritin, GPX4 and lipid droplets to increase iron accumulation and lipid peroxidation, thereby promoting ferroptotic cell death.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSRYSYQSLLDWLYGGVDPSFAGNGGPDCAAFLSWQQRLLESVVVLTLALLEILVALRHILRQTKEDGRGSPGSQPEQVTQRPEEGKESLSKNLLLVALCLTFGVEVGFKFATKTVIYLLNPCHLVTMMHIFLLACPPCRGAIVVFKLQMHMLNGALLALLFPVVNTRLLPFELEIYYIQHVMLYVVPIYLLWKGGAYTPEPLSSFRWALLSTGLMFFYHFSVLQILGLVTEVNLNNMLCPAISDPFYGPWYRIWASGHQTLMTMTHGKLVILFSYMAGPLCKYLLDLLRLPAKKID
Protein: L-fucose kinase (Fucokinase) (EC 2.7.1.52) (Q8N0W3)
Organism: Homo sapiens (Human)
Function: Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.
Interaction partners:
- Fucose-1-phosphate guanylyltransferase
- Sorbitol dehydrogenase
- GDP-L-fucose synthase
- Galactose mutarotase
- Hexokinase HKDC1
- Hexokinase-1
- Hexokinase-3
- Hexokinase-2
- Ketohexokinase
- GDP-mannose 4,6 dehydratase
Sequence:
MEQPKGVDWTVIILTCQYKDSVQVFQRELEVRQKREQIPAGTLLLAVEDPEKRVGSGGATLNALLVAAEHLSARAGFTVVTSDVLHSAWILILHMGRDFPFDDCGRAFTCLPVENPEAPVEALVCNLDCLLDIMTYRLGPGSPPGVWVCSTDMLLSVPANPGISWDSFRGARVIALPGSPAYAQNHGVYLTDPQGLVLDIYYQGTEAEIQRCVRPDGRVPLVSGVVFFSVETAERLLATHVSPPLDACTYLGLDSGARPVQLSLFFDILHCMAENVTREDFLVGRPPELGQGDADVAGYLQSARAQLWRELRDQPLTMAYVSSGSYSYMTSSASEFLLSLTLPGAPGAQIVHSQVEEQQLLAAGSSVVSCLLEGPVQLGPGSVLQHCHLQGPIHIGAGCLVTGLDTAHSKALHGRELRDLVLQGHHTRLHGSPGHAFTLVGRLDSWERQGAGTYLNVPWSEFFKRTGVRAWDLWDPETLPAEYCLPSARLFPVLHPSRELGPQDLLWMLDHQEDGGEALRAWRASWRLSWEQLQPCLDRAATLASRRDLFFRQALHKARHVLEARQDLSLRPLIWAAVREGCPGPLLATLDQVAAGAGDPGVAARALACVADVLGCMAEGRGGLRSGPAANPEWMRPFSYLECGDLAAGVEALAQERDKWLSRPALLVRAARHYEGAGQILIRQAVMSAQHFVSTEQVELPGPGQWVVAECPARVDFSGGWSDTPPLAYELGGAVLGLAVRVDGRRPIGARARRIPEPELWLAVGPRQDEMTVKIVCRCLADLRDYCQPHAPGALLKAAFICAGIVHVHSELQLSEQLLRTFGGGFELHTWSELPHGSGLGTSSILAGTALAALQRAAGRVVGTEALIHAVLHLEQVLTTGGGWQDQVGGLMPGIKVGRSRAQLPLKVEVEEVTVPEGFVQKLNDHLLLVYTGKTRLARNLLQDVLRSWYARLPAVVQNAHSLVRQTEECAEGFRQGSLPLLGQCLTSYWEQKKLMAPGCEPLTVRRMMDVLAPHVHGQSLAGAGGGGFLYLLTKEPQQKEALEAVLAKTEGLGNYSIHLVEVDTQGLSLKLLGTEASTCCPFP
Protein: Cyclin-L2 (Cyclin Ania-6b) (Paneth cell-enhanced expression protein) (PCEE) (Q9JJA7)
Organism: Mus musculus (Mouse)
Function: Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.
Subcellular location: Nucleus speckle {ECO:0000250|UniProtKB:Q96S94}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q96S94}.
Interaction partners:
- DDB1- and CUL4-associated factor 1
Sequence:
MAAAAAGAAGLMAPASAACSSGSAGAAPGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDVDTETGLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLVLDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTAWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICFKILQLYTRKKVDLTHLESEVEKRKHAIEEAKARAKGLLPGTAPGLDSAAGFSPAPKLESPKEGKGGKPSPPSGKSAKRKMEGPKKAQGHSPVNGLLKGQESRSQSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQVHRGAPYKGSEVRGSRKSKDCKYLTQKPHKSRSRSSSRSRSRSRERTDNSGKYKKKSHYYRDQRRERSRSYERTGHRYERDHPGHSRHRR
Protein: Cytoplasmic linker associated protein 1 (A0A8I6AEZ5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Golgi apparatus, trans-Golgi network {ECO:0000256|ARBA:ARBA00004601}.
Interaction partners:
Sequence:
MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSSSSKAPSSSRRNVSMGTTRRLMASSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTASRGSTVSTKSMSTTGSLQRSRSDIDVNAAASAKSKVSSSSGSTAFSSAAALPPGSYASLDGTATKAEGRIRTRRQSSGSTTNVASTSSDSRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLAGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFTPLDRFGLGQSGRIPGSVSAMRVLSTSTDLEAAVADALLLGDARSKKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNAGVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLSKPPPPFSQPNSIPTAPSHKTLRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDIVSRDGGAASPATEGRGGSEVEGGRMALDNKTSLLNTQPPRAFPGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERITKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
Protein: Putative F-box/kelch-repeat protein At5g28160 (Q3E8Y7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MNSEVERPSFLSLPDEIILSCLARISRSYYPKLSLVCKTFRTLLISNELIVARLHLKTHETFCHVCLKFPDKPNPSMFTLWIKPGTILTNQLEKNKRSTRDTRLVQIPSSYYYNVPFYLVMVGSEVYGLSQRNDPSSNMFVRNKGDIFLCKAPNMTVARAKASAVVFNGKIYVMGGCMADESVNWGEVFDIKTQTWEALPDPGPEFRFSSIRKIDVFQEKLYVRSNEKKDSVYDPKEEWRVVKGLDMLNRNLGCGTIEIVHYGGKLLILWDKVDLSHDKDIWCAVIALEKRHGSDEVWGNIEWADIVLTVPSSYVFVNSLETGF
Protein: Serine-rich single-pass membrane protein 1 (Q8WWF3)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Sperm acrosome membrane-associated protein 1
Sequence:
MGDLFSLFWEVDPPPIPVNCAIPNQDYECWKDDSCGTIGSFLLWYFVIVFVLMFFSRASVWMSEDKKDEGSGTSTSVRKASKETSCKRQSKDSAWDPSQTMKKPKQNQLTPVTNSEVALVNAYPEQRRARRQSQFNEVNQNQHDSDTTEYGSEESNSEASSWKESESEHHPSPDSIKRRKMAQRQRNLGSYQMSERHCLHCKALRTNEWLAHHSRQKPSVTPPMKRDSQEESSISDINKKFSKF
Protein: Smog, isoform F (M9PEK9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MELCIATKSKIETAQSSMPQSSQCSSSSNCRNYQKKCHQNQTNTQVQSTQRSNCSSHSDRDHLTNQQKQQNQRTNSATAASAAAATLSESTRCNIIISSSSSSSSSTKSSKNIREPSSSSSTQLNTLYSLLVLLIVGLATATASPSPSPSHAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHDANGLDFDELTPTASSVSALSRAERFRLRKRSATPTTPATAAGVTSLDVATAAAAATDAAAKDAGSGKKPEEKCEPKVLETLPDEPFYDYTDIAEDAARQFIEFLSGKFPNANTPIAIDEPTRAEVSRRANGIASYALNEDDNLLAFAIAAPSIHTVVVKFRDNVTIPPDQVHNKAYLGSYWRELGAAWNSTDGTQEWGAPFRDCNLLTRRWLWPFRISFSEHRIKVVAAAFIAADEDVCNDGLEEVFGRRHGCDRNTTFCLLTENKPAATRDVYTCLCRESYYLPNSTLQGFRGDRVELSEGYDNYSCIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVAIVLGACILCCIVLGVIVFRQRKCKAIASGMWTVLETILLGIVLLYASVAVHFFPASTERCLLEPWLRELGFITCYGAIILKLYRHLVDFRTRKAHRWVLRDVDLLKYLGTMVFAVICYMAAFTASSLDLLESAQLESLREADTNTCHPLKWELVTQTSEMLILCFGLHLSIASRNANTQFRERQFLVTALTLEFLVSSSFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLIFVPKLWYQHKQGTSHDAGQRLGGGYAGLCLGDPDIGELTISEMSPEDIRAELKRLYTQLEIMKNKTLRQDNPHISKRRGGRKAGHRRFSLQALSAKHRSNKHHQDIEITEAEPSRTPEDSVCSAEGPTDTYAEISGVSHSMLSHSMVSHSVVSHSK
Protein: Benzoate 4-monooxygenase bphA (EC 1.14.14.92) (Benzoate-para-hydroxylase A) (BpH) (Cytochrome P450 monooxygenase cyp53A1) (A2QTW5)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Function: Cytochrome P450 monooxygenase; part of the benzoic acid degradation pathway also known as the protocatechuic acid pathway. Benzoic acid debradation begins with the conversion of benzoic acid into 4-hydroxybenzoic acid through hydroxylation by the benzoate-4-monooxygenase bphA, and its partner NADPH-cytochrome P450 reductase cprA which act as a mediator in electron donation from NADPH. 4-Hydroxybenzoic acid is then converted into 3,4-dihydroxybenzoic acid (also called protocatechuic acid) by the p-hydroxybenzoate-m-hydroxylase phhA (Ref.5). Protocatechuic acid is converted into 3-carboxy-cis,cis-muconic acid by the intradiol ring-cleavage dioxygenase prcA, which is further metabolized through the 3-oxoadipate pathway to finally enter the tricarboxylic acid cycle (TCA) (Ref.5).
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLALLLSPYGAYLGLALLVLYYLLPYLKRAHLRDIPAPGLAAFTNFWLLLQTRRGHRFVVVDNAHKKYGKLVRIAPRHTSIADDGAIQAVYGHGNGFLKSDFYDAFVSIHRGLFNTRDRAEHTRKRKTVSHTFSMKSIGQFEQYIHGNIELFVKQWNRMADTQRNPKTGFASLDALNWFNYLAFDIIGDLAFGAPFGMLDKGKDFAEMRKTPDSPPSYVQAVEVLNRRGEVSATLGCYPALKPFAKYLPDSFFRDGIQAVEDLAGIAVARVNERLRPEVMANNTRVDLLARLMEGKDSNGEKLGRAELTAEALTQLIAGSDTTSNTSCAILYWCMRTPGVIEKLHKVLDEAIPQDVDVPTHAMVKDIPYLQWVIWETMRIHSTSAMGLPREIPAGNPPVTISGHTFYPGDVVSVPSYTIHRSKEIWGPDAEQFVPERWDPARLTPRQKAAFIPFSTGPRACVGRNVAEMELLVICGTVFRLFEFEMQQEGPMETREGFLRKPLGLQVGMKRRQPGSA
Protein: Cytosolic invertase 1 (OsCYT-INV1) (EC 3.2.1.26) (Q69T31)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Cytosolic invertase that cleaves sucrose into glucose and fructose and is involved in the regulation of primary root elongation, lateral root formation, floral transition and pollen development.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9LQF2}.
Interaction partners:
Sequence:
MELAVGAGGMRRSASHTSLSESDDFDLSRLLNKPRINVERQRSFDDRSLSDVSYSGGGHGGTRGGFDGMYSPGGGLRSLVGTPASSALHSFEPHPIVGDAWEALRRSLVFFRGQPLGTIAAFDHASEEVLNYDQVFVRDFVPSALAFLMNGEPEIVRHFLLKTLLLQGWEKKVDRFKLGEGAMPASFKVLHDSKKGVDTLHADFGESAIGRVAPVDSGFWWIILLRAYTKSTGDLTLAETPECQKGMRLILSLCLSEGFDTFPTLLCADGCCMIDRRMGVYGYPIEIQALFFMALRCALQLLKHDNEGKEFVERIATRLHALSYHMRSYYWLDFQQLNDIYRYKTEEYSHTAVNKFNVIPDSIPDWLFDFMPCQGGFFIGNVSPARMDFRWFALGNMIAILSSLATPEQSTAIMDLIEERWEELIGEMPLKICYPAIENHEWRIVTGCDPKNTRWSYHNGGSWPVLLWLLTAACIKTGRPQIARRAIDLAERRLLKDGWPEYYDGKLGRYVGKQARKFQTWSIAGYLVAKMMLEDPSHLGMISLEEDKAMKPVLKRSASWTN
Protein: Myotubularin related protein 1 (Q7KPF5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
HKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIA
Protein: LD32549p (Q95TP6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSAAAASRDITLFHAMNILHKHEYSIEESMSSLVPSTGPVLCRDEIEDWSASEANLFEEALEKYGKDFNDIRQDFLPWKTLKQIIEYYYMWKTTDRYVQQKRVKAVEAELKLKQVYIPQYNNNGKGNGTSTKAGGGIYNGTTNGSTDLSSNGKPCESCGTTKSSQWNSVSSGHSTSRLCLSCWEYWRRYGSMKSATKGDAGEGDAKKKSSSAASTPTATLAGLATTPTAVVDLNDDEKISDLTNRQLHRCSIVNCGKEFKLKTHLARHYAQAHGIAISSGSPRPIMKTRTAFYLHTNPMTRVARAICRSIVKPKKAARQSAYAINAMLVKQEFTNRISGKSQAEIKKLLLLKPKDRGSVTKIANRLGAPGSGPHEWLVLTPKDKMPLPAVVSFPKPPKAPDGSLVYDRVPNKSPDVVAVPADKELTIIPTQATSTIRKRAHEDQQLNGTEVTIVPSGPPAKRPNKDPMPSHCPSPEQFAAMMAASGQPLSRHHLNGKQKIAQMARGGNGRKQVISWMDAPDDVYFRANDTHKKTRKILSAVDLRRAARKPWRTLPIKPAAPEPSSRPIESQIVILD
Protein: Protein SSO2 (P39926)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for vesicle fusion with the plasma membrane.
Subcellular location: Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Interaction partners:
- Synaptobrevin homolog 1
- Synaptobrevin homolog 2
- Protein transport protein SEC9
- Protein transport protein SEC1
- Exocyst complex component SEC3
- Sporulation-specific protein 20
- Alpha-soluble NSF attachment protein
- Protein SSO1
- Synaptobrevin homolog YKT6
- Protein transport protein SEC22
Sequence:
MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVSEEQEMELRRSLDDYISQATDLQYQLKADIKDAQRDGLHDSNKQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK
Protein: Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) (P9WQ07)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00004}.
Interaction partners:
- GMP synthase
- Hypoxanthine-guanine phosphoribosyltransferase
- Purine nucleoside phosphorylase
- Probable nucleoside hydrolase IunH
- Adenylosuccinate lyase
- Guanylate kinase
- Bifunctional purine biosynthesis protein PurH
- Adenosine kinase
- Adenylate kinase
- Uracil phosphoribosyltransferase
Sequence:
MLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSAISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASGADLVAGVDARGFLVAAAVATRLEVGVLAVRKGGKLPRPVLSEEYYRAYGAATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAVVVELAGLSGRAALAPLPVHSLSRL
Protein: Forkhead box protein P2 (P0CF24)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity). Plays a role in synapse formation by regulating SRPX2 levels.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Forkhead box P4
- T-box brain transcription factor 1
- Nuclear factor of activated T-cells 2
- C-terminal-binding protein 1
- Homeobox protein cut-like 1
- BCL11 transcription factor B
- Homeobox protein Nkx-2.1
Sequence:
MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQCQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSQEDNGIKHGGLDLTTNNSSSTTSSTTSKASPPITHHSIVNGQSSVLNARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE