wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized family 31 glucosidase C30D11.01c (EC 3.2.1.-) (Q09901)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Alpha-glucosidase
- Putative beta-glucosidase
- Probable glucoamylase
- Alpha-galactosidase mel1
- Hexokinase-1
- Hexokinase-2
- Invertase
- Putative invertase
- Glucan 1,3-beta-glucosidase
- Alpha-glucosidase
Sequence:
MLLFKFNFTTAFLFTILAFAQARSHSSSSSSTSKSSASHHSSINSTSATSVYDFSSLTTPIVPTNGVAQEPTLYESSRGLSCPGYQARNISEYSYGVLAILELAGDACYAYGTDYPYLLLNVSYDTEERVHISISDLNQTQFQLSNRRDVWDAPLFYRSSNFSGNLQYNFSFNTDPFEFWITRIADDQVLFDTRGNPLIFEDQYIELTTNMVEDYNVYGLSGSQQSFRLGNNLTKTFWATGYSDSPEANMYGSHPFYMEQRYIPIGTTNTYTSASHGVLMLSSNGMEVLLRSTYIKYRMIGGIIDLFVYSGSTVSPKYTIQQYVQSIGTPTMQPYWSLGFQMSRWGYKTLSDLINMRSYLNASNIPTEGFWNDIDYMSEFRTFTVNSTAFPPNQTLDFFRSLDESHQHYVPVLDPAIYAANPNKSADRTYYPYYSGFEDNIFIKNPNGSAYVGMAWPGFVVYPDFTNPAVLQYWKQGILNLSTAFGSNYSYDLPFSGLCLDMNEPTSFCIGSCGSDLLKLNPVHPPFSLPGDVDNKVYSYPEDFNATNTTEYKSVSRASQSQYKATATSEKSHETPSSESLINGKPEFSINYPPYALDTDTETHDLAQFGVSPNATMHGNTLRYNLFNTYGYSESKISFEALNSIQPNIRPFLLSRSTFVGSGRYAAHWLGDNKSQWSDMVSSISSILTFNLLGIPMVGADVCGYNGNTDEELCARWMALGAFLPFYRNHNSLGSIPQEPFRWASVAEASRSAIEIRYSLLPYWYTLMHTASVDGTPMVRPLFFEFPKQISLASVDKQFMIGTALLISPALEPNTTYIQGIIPGDNDTIWYDWYNHSVINHDYDENITMSAPLGYVNIAVRGGNIIPLQQPGYTTYESRNNPYSLLIAMDNNGFASGSLYIDDGISMQTNSSLSVKLNSNSNTITCVVSGTMVSSPSLANITILGLSNPPNTILFNGQQLSDYQYSDQTLSLTNLLDLTVDGAFSKNWTVTWS
Protein: Growth hormone (Q0QBE6)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLLLAFTLLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLRQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKSEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFREDLHKTETYLRVMKCRRFGEASCAF
Protein: Uncharacterized protein (Q38E08)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DM10 domain-containing protein
- EF-hand domain-containing family member C2
- Rib72 protein-like protein
- CFA20 domain-containing protein
- Cilia- and flagella-associated protein 45
- Enkurin domain-containing protein
- Enkurin domain-containing protein
Sequence:
MAFSRKERKQLLRDRDLVPQLAESPFGPFPPGYGIKNDITVTKKGCVVRGDPATKPASADVQKRGKQDTESDQRPKQILVGHTGTGGMTFSTFKNNGFRQSLKIGCFGDPKGPEKAGAYRKRVIPPTEFRNYYVRGDLPLTIQQGASRTLSWRLNVSSLDYHHFLPIFFDGLRELEEPFIFVALQGCYDLLERGGDKILPTIPQLIVPIKTALNTRHPTVIINVLKVLQKLVESADFVGQALVPYYRQILPVFNLYKNRNKNIGDRIDYSQTKRQNISDLVNETLHLLEQYGGEDAYINIKYMVPTYESCLM
Protein: BcDNA.GH11973 (Regeneration, isoform A) (Regeneration, isoform D) (Q9Y102)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MCGSHKMWCCQVFILALFAHTIAVEFHGSAARAEINFEGPSPAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAQPLDNNCAIYDPSLKYRWSARPCSDKLRFICQHKMPKVSGPNRYKIYNRWNATYPNEQANEVVLEILEPRENDRRYHRRVKAEDSDEEMIIPDRRRNNNRRNNHRNRQIKNQNQHPNDVNYQPAQQRQRNRPRTSTVAPTTTQSVSQSNDVLAPSPTPQQMTQYDRKLQRQRERERRRQLRRQERQKLAREQKRERQRRLKEERQRLQREEQQRRQRLHHDEPKPQVNPQVKPQVIDELRQRSGEDLDKNQTDEHEQKLRNEQEKKLREEQQKQRDEQEQKDREEQDRLKQEEEQARTHQKELKENQEQQLRELKAKQEREKQERDYQQQKREHELELLKQRQAEADRQHAADEEAEKLRLERIQKQRELEAQQRREREEQRRKQREEQEEQDRQNHAKRLAEEKRLHDLYAERIRLANTEREKQLAEAHEAKRLEELKLQEQLKKQEDERQEQIRREQEEEEKRLELERLEEARRFEEKELKRLHEENQRREEQKLQREREIALREAAEKKLAEEEEMLRKEVAEEERKVKQRLEDEMRQAEEARKAKEAEERAAEEAKAAEQKRRVEAAKKKADEEVKAKLEEKRREYVTRISALSPEDQKKFIEMRKRRKQLKEKKERDQRAKELKRIQQAMRLDDNE
Protein: Pyruvate carboxylase (EC 6.4.1.1) (Q0E9E2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
- Probable citrate synthase, mitochondrial
- Citrate synthase
- Phosphoenolpyruvate carboxykinase
- Phosphoenolpyruvate carboxykinase
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- L-lactate dehydrogenase
- Malic enzyme
- ATP-citrate synthase
- Malic enzyme
Sequence:
MFIPAAQSAYRTLRKTQPRVRLNAIFKNGYSSKVEYKPIRSVLVANRGEIAIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKGLPPVEAYLNIPELIRVCKENDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGDKVAARVAAIEAGVPIVPGTDGPVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESFQRASSEAKAAFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQKVVEIAPAPRLPIEIRDKMTEAAVRLARHVGYENAGTVEFLCDESGNFYFIEVNARLQVEHTVTEEITGIDLVQSQIRVAEGMTLPELGYTQDKIVPRGYAIQCRVTTEDPANDFQPNTGRLEVFRSGEGMGIRLDSASAYAGAIISPYYDSLLVKVISHASDLQSSASKMNRALREFRIRGVKTNIPFLLNVLENQKFLHGVLDTYFIDEHPQLFKFKPSLNRAQKLLNYMGEVLVNGPQTPLATTLKPALVSPHVPEVPLDLSPEAIEREERGEAKVTEPPKGLREVLVCEGPEAFAKEVRNRKELLLMDTTFRDAHQSLLATRVRSHDLLKISPYVTHKFNNLYSLENWGGATFDVALRFLHECPWERLEEMRKRIPNIPFQMLLRGANAVGYTSYPDNVVYKFCELAVQTGMDIFRVFDSLNYLPNLILGMEAAGKAGGVVEAAISYTGDVSDPKRTKYDLKYYTNLADELVKAGTHVLCIKDMAGLLKPESARLLITAIRDKHPDIPIHIHTHDTSGAGVASMLACANAGADVVDVAVDSMSGMTSQPSMGAVVASLQGTPLDTNLDLRTVSEYSAYWEQTRTLYAPFECTTTMRSGNADVYLNEIPGGQYTNLQFQAFSLGLGDFFEDVKKAYREANLLLGDIIKVTPSSKVVGDLAQFMVQNDLTADQVLERAEELSFPKSVVEYLQGSIGIPHGGFPEPLRSRVLKDMPRIEGRPGAELKDLDFDKLKKELQESHTCVTNRDVMSAALYPQVTNDFLNFREKYGPVDKLDTRIFLTGPKVGEEFDVPLERGKTLSVKALAVSADLKPNGIREVFFELNGQLRAVHILDKEAVKEIHVHPKANKSNKSEVGAPMPGTVIDIRVKVGDKVEKGQPLVVLSAMKMEMVVQSPLAGVVKKLEIANGTKLEGEDLIMIIE
Protein: ER membrane protein complex subunit 8/9 homolog (Protein EMBRYO DEFECTIVE 2731) (Q9FG71)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- ER membrane protein complex subunit 3
- ER membrane protein complex subunit 4
- ER membrane protein complex subunit 1
- ER membrane protein complex subunit 2
- ER membrane protein complex subunit 2
- Membrane magnesium transporter
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 7 homolog
- ER membrane protein complex subunit-like protein
- ER membrane protein complex subunit 10
Sequence:
MGMGSNGELKYEISQNAYIKLVLHSLRHKTAAVNGVLVGRISPKDDGVVEISDSVPLFHSNLALLPPLEISLIMIEEHYVAQGLSIVGYFHANERFDDVELCGVAKNIGDHISRYFPQAPILLLNNKKLEALSKGKERSPVMQLCVKDASKNWRVVGADGGSKLLLKEPSANVVLSDYISSEKWKDVTDVDDHLDDVTKDWLNPGLFN
Protein: EamA domain-containing protein (Q580H7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MASQNAATNGDGVTAYRTESASLMNDNKRRNDKQTEDQRPPFTVGSYALGIVMILCVAVIWTYASVLIQYIYEAEEYEKPYFMTYFNTNTFAVNNIGFLLLSSWRRLPWKNGERTSSLVIYDDALKRTFVSGASAPDNEPADGADVSRGGPQSEAERIRPYSKFRVFKCAAFFCPIWFLANSLFNASLAATSVSSVTVLSNTSAIWTFLLSLIFFNQKATWPCLLAMTMTIIGACLVGFSDAENTENETVGGDIYALLAAIFYAVYTSIIRWHASDDDRYSILMLFGFVGALNTILFWPLLLIFHFTDFETFQTPGGIQFALLLVNALVGTNLSEVLWARAVLLTSPTAATLGLTLTTPLAMTSDLLIKQKSFNAMYIIGAVLLTLGFICFNLEQQLMKLLKGSRSS
Protein: PE family protein (Q7D7A7)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSARRADGGRDEQLLLLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASGSGRPWDRDQLLRALGLRPPGHE
Protein: Ganglioside-induced differentiation-associated protein 1 (Q78AN2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAVENIGEGESQDEKEILIKKDAQDSGEIVESTKTKASKLILYHWTQSFSSQKVRLAIAEKGLQCEDYDVSLPLSEHNEPWFMRLNPTGEVPVLVHDNHVICDPTQIMDYLEQNFCDEQTPKLIPEEGSTYYHRVQHYRELLDSLQMDAYTHGCILHPEITVDSHIPAYATTHIRTQIGNTESELKKLAVENPDLKDAYIAKQRRLKSKLFDHDNMKYLKKLLDELENVLDQVETELQRRSEETPEEGSQQAWLCGDFFSIADVSLAVTLHRLKFLGLSRRYWGNGMRVNLETYYERVLDRPTFRRVLGHVNNILISAVLPTAFRVAKKKAPAFVGATLLVGLIGGATYLAFIYFKKRLLVS
Protein: Probable beta-1,3-galactosyltransferase 2 (EC 2.4.1.-) (A8MRC7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal glycosyl residue.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Beta-1,6-galactosyltransferase GALT29A
- Actin-related protein 9
Sequence:
MSAKIKGEYSSRSFVSRKWTILLCLGSFCVGMFFTNRMWNIPESKGMSHPSVTEAERLKLVSEGCNPKALYQKEVKRDPQALFGEVANTHIALQTLDKTISSLEMELAAARSVQESLQNGAPLSDDMGKKQPQEQRRFLMVVGINTAFSSRKRRDSIRATWMPQGEKRKRLEEEKGIIIRFVIGHSATTGGILDRAIEAEDRKHGDFLRLDHVEGYLELSGKTKTYFSTAFSMWDADFYVKVDDDVHVNIATLGETLVRHRKKPRVYIGCMKSGPVLSQKGVRYHEPEYWKFGENGNKYFRHATGQLYAISRDLASYISINQHVLHKYANEDVSLGAWFIGIDVKHIDDRRLCCGTPPDCEWKAQAGNICVASFDWSCSGICRSADRIKEVHRRCGEGEKALWSATF
Protein: Cystatin-S (Cystatin-1) (Protein LM) (P19313)
Organism: Rattus norvegicus (Rat)
Function: This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MAYLLHAQLFLLTTFILVLNMRLCPVLGHFLGGIEKSSMEEEGASEALNYAVNEYNEKNSDLYLSRVVEVKDVQKQVVAGTKFFFDVILGKTICLKTQGDLTNCPLNEEADQQEHEFCSFVVHDIPWENYIVLLSSSCHSI
Protein: Ricin [Cleaved into: Ricin A chain (EC 3.2.2.22) (rRNA N-glycosidase); Ricin B chain] (P02879)
Organism: Ricinus communis (Castor bean)
Function: Ricin is highly toxic to animal cells, and to a lesser extent to plant cells.
Interaction partners:
Sequence:
MKPGGNTIVIWMYAVATWLCFGSTSGWSFTLEDNNIFPKQYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAPPPSSQFSLLIRPVVPNFNADVCMDPEPIVRIVGRNGLCVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYSPGVYVMIYDCNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQPFVTTIVGLYGLCLQANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASSGQRWMFKNDGTILNLYSGLVLDVRASDPSLKQIILYPLHGDPNQIWLPLF
Protein: Vacuolar membrane amino acid uptake transporter fnx2 (O59726)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: MFS-type transporter involved in vacuolar amino acid uptake.
Subcellular location: Vacuole {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}. Membrane {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Vacuolar amino acid transporter 5
- Uncharacterized amino-acid permease C965.11c
- Autophagy-related protein 22
Sequence:
MSNPRTKSPNTNRGQGLRSERSALLNDSLSSLNGNSSYDSIKDSSKNNKDVAEVNEYPRRPESSVSVVSNSPHRQDAATTNTVSTVSVSKVLPALLLGVVLAALDNTIVASTYTKIGAEFGKFSQVSWTATAYMISCTAFQPLFGKFCDIYGRKKTLLAAYCVFGIGCFLCGTSRSLWQLVAARAIAGIGGGGMNSTVSILMSDIVPLKQRGTYQGIINVFFAIGSSLGGPVGGYFADQYTWRIGFLIQVPLIAIAFLCVYFTLNLPHHNHVSFMTRFRKIDLKGLILLIIGVTTMTCAFTLGGNVREWNDPVVISLLIASSISYLSFVYVEAFVAFEPLAPMDVLTERTCLSSYLCNFFHSVANFGWIYGMPLFFQSIKNEGAEKSGIRLIPMIIGSSLGSLLGGAVISLTGNYKKITVGSYFFGSVAALFMLRYGYSNFNWEYAVYPFSGGLGNGIAVTTTLVAIIHASPSAFQASAIATSYLFRSNGCVLGVSISSSIVQTVLGIKLRKSLDFDVDELLHHLRKDISYVHRLPEEIRQTVLDALLGSIHYSFLFVSFMFFCAFVCSMFIKNRNL
Protein: Major facilitator superfamily (MFS) profile domain-containing protein (H2FLL9)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSSRKVMVFVVTFVSYGLYHASRKALSGVKSSIKADWLSNSSGHAPLFTNEADAKHFLGSLDAIFMAAYAAALFFWGWLGDRLNPKLVVAAGMVGSAVTLTLFGAIPKWFNFYHAPYYIMTYVAFGLVQACGWPSEIAIMANWFGKGNRGFVMGVWAACQPVGNIFGSIFTAMVLPLGYQYTFVFNSVLIALGAIVVVMAIDSSPNEEHEDGVEANRIRLLRRSSSSEPHHNFHGEPISLFKAVLLPGVLAYCICNACLKLVNYAFFFWLPLYLTDAYHWEESQADQLSIWYDFGGIIGSVLGGYITDKMGKRSPLIVAMLVCSIGSLYFYAHVGPHMFWNAVVMTTVGVTVSGPYNLIVGSISIDLGSQPALAGNTQAMSTVSGLLDGTGSAGSAVGQLLIPIIQDDLGWKAVFYVFMLLNGFAILAILKRCIIDLKSLRKLRSGEESPLLNDEAGDHED
Protein: Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase) (Q8R3F5)
Organism: Mus musculus (Mouse)
Function: Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondria.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q8IVS2}.
Interaction partners:
- 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
- Acyl carrier protein, mitochondrial
- Fatty acid synthase
- Acetyl-CoA carboxylase 2
- Acetyl-CoA carboxylase 1
- Partner and localizer of BRCA2
- Malonate--CoA ligase ACSF3, mitochondrial
- Small ribosomal subunit protein bS16m
- Malonyl-CoA decarboxylase, mitochondrial
- GTPase Era, mitochondrial
Sequence:
MSARVARAGWAWRSWGRRAASSLREPPPDAVDVAELLRDSSVAEEGAQEAVARRRPPSQCSVLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFSVGEFAALVFAGAMDFSEGLYAVKARAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCKSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDPLMKVLGSINIKKPLVAVHSNVSGQKYTHPQHIRKLLGQQVVSPVKWEQTMHSIYERKKGMEFPSTYEVGPGQQLGSILKCCNRQAWKSYSHVDVMQNIMDPDP
Protein: Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II) (Q9NVP2)
Organism: Homo sapiens (Human)
Function: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for gonad development.
Subcellular location: Nucleus {ECO:0000269|PubMed:12842904}. Cytoplasm, cytosol {ECO:0000269|PubMed:22407294}.
Interaction partners:
- Nuclear autoantigenic sperm protein
- Histone H3.3
- DNA replication licensing factor MCM2
- Chromatin assembly factor 1 subunit B
- Histone H4
- Histone H3.2
- Histone H3.1
- Protein HIRA
- Serine/threonine-protein kinase tousled-like 2
- Histone H3.1t
Sequence:
MAKVSVLNVAVLENPSPFHSPFRFEISFECSEALADDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQLQRNILASNPRVTRFHINWDNNMDRLEAIETQDPSLGCGLPLNCTPIKGLGLPGCIPGLLPENSMDCI
Protein: Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin) (O14653)
Organism: Homo sapiens (Human)
Function: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:21549339}; Single-pass type IV membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:9349823}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O35165}. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. {ECO:0000250|UniProtKB:O35165}.
Interaction partners:
- BET1 homolog
- Vesicle-trafficking protein SEC22b
- Sec1 family domain-containing protein 1
- Golgi SNAP receptor complex member 1
- Syntaxin-5
- BET1-like protein
- Synaptobrevin homolog YKT6
- General vesicular transport factor p115
- Vesicle-trafficking protein SEC22a
- Vesicle-trafficking protein SEC22c
Sequence:
MDPLFQQTHKQVHEIQSCMGRLETADKQSVHIVENEIQASIDQIFSRLERLEILSSKEPPNKRQNARLRVDQLKYDVQHLQTALRNFQHRRHAREQQERQREELLSRTFTTNDSDTTIPMDESLQFNSSLQKVHNGMDDLILDGHNILDGLRTQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCVVMFLVVQYLT
Protein: Major ampullate spidroin 1 (Q05H60)
Organism: Euprosthenops australis
Interaction partners:
Sequence:
MSWTARLALLLLFVACQGSSSLASHTTPWTNPGLAENFMNSFMQGLSSMPGFTASQLDDMSTIAQSMVQSIQSLAAQGRTSPNKLQALNMAFASSMAEIAASEEGGGSLSTKTSSIASAMSNAFLQTTGVVNQPFINEITQLVSMFAQAGMNDVSASASAGASAAASAGAPGYSPAPSYSSGGYASSAASAAAAAGQGGPGGYGPAPNQGASSAAAAAAGSGQGPSGPYGTSYQISTQYTQTTTSQGQGYGSSSAGAAAAGAAGAGQGGYGGQGQGGYGQGAGGAAAAAAAAAAAAAAAGQGGQGGGGYGQGGQGGQGGQGQGGYGQGAGSSAAAAAAAAAAAAAAGRGQGGYGQGSGGAAAAAGSGQGGYGGRRQGGYGQAAAAGQGGQGGQG
Protein: Corticosteroid-binding protein (P31225)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: May be a flavoprotein with enzymatic activity.
Interaction partners:
- Ornithine decarboxylase
- Spermidine synthase
- Aldehyde dehydrogenase domain-containing protein
- Aldehyde dehydrogenase
- Agmatinase
- Afp99p
- Spermine synthase
- Amine oxidase
- Amine oxidase
- Polyamine oxidase
Sequence:
MSRTKSTKVLIIGAGVSGLKAAETILSKSFLTGDDVLVVEAQNRIGGRLKTTDTSQSKLGINYDLGASWFHDSLNNIVLNHMINDGLLDDEKDVYFDDKDLKTFSSTGEVPIVDKKLNRVLEDIEKYIQLYFNRNLGVPDLSLRDIVAQYFEKYNRLITEEQREYCGRMMRYLEFWFGISWDRISGKYAVTTHQGRNLLNKKGYGYLVESLAKRIPESSLLLEEPVNKIIRNNKDAGKRVLVETINGLQIFCDYLIVTVPQSILSLEESSPYSIKWEPKLPQRLVESINSIHFGALGKVIFEFDRIFWDNSKDRFQIIADHTDGDLSRELTELPKPFTYPLFAVNFGRVHNGKASLVILTQAPLTNYLETHPDQAWQYYQPMLQKLSINDEPIPDPINTIVTDWTTNPYIRGSYSTMYTNDDPSDLIISLSGDFEDLGISEPYIKFAGEHTTSEGTGCVHGAYMSGIYAADCILENIFRNDVTGYTIIG
Protein: TIGR00153 family protein (Q9HTY2)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Phosphate transporter
- Copper resistance protein D domain-containing protein
- Probable transcriptional regulator
- Phospholipase
- Uncharacterized protein
- Major facilitator superfamily
- FAD-binding PCMH-type domain-containing protein
- UspA domain-containing protein
- Hypothetical protein
- UspA domain-containing protein
Sequence:
MPTNPFISLFGRSPIGPMQQHIAKAHECAAGLLPFFRAVIAEDWAQVEQVQQDMVRLEQEADRLKKHVRMHLPKSLFLPVPRSDLLELLSVQDKVANRAKDIAGLMLGRRMRIPLPLQGQMLAYVQRSVDASAQALRVVNELNELLETGFGGRETSLVESMVEELEAIENDTDRIQVEVRRELFRLESELPPVDVMFLYQIIEWIGDVADRAQRVGNRLEQLLAR
Protein: Mirror, isoform A (Mirror, isoform B) (Q9VU01)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MTVHSNETGICLVMNAVSTHLATSSPNTPPTNAPQSPPSTLPTLACPAAQPLSAPGIAGPGHSGMVTSTVPPGARSTSPCGPSAGLPALSLVGAPPPGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDPVSGQTICSCQYDMLNYQRLAAAGGVPLGVYPEGMSAYLSGIAADQPPFYANPAGIDLKENLVAGASPWPYPSMYHPYDAAFAGYPFNSYGMDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNRVDDDDANIDDDDDKNTEDNDLLDAKDSGVGSTDDKDRSGRLGDMMTDRPGESNNSEWSESRPGSPNGSPDLYDRPGSMPPGAHPLFHPAALHHHFRPPAGSPPDIAAYHHHQQQLLQQHQQAQQNSLQTAVGGTAKPRIWSLADMASKDSKDSSSGAKDNHPELPPAHPGFYGHPGQQPSPGKILSPLAARIPNYSPYVRPDLYRGFYGPAAAHLGAPTQEFLEHQRTFGASLAAHNGPLGMNPLLWKAAVSGAANGHHFAPLSLTTSGGSSGGQQVAPPPVASPSASSSSSSMGCDVVHIPTSSGQSAAQHMMGPISSNSTASSSSSHSGKISPGVNVTSLSAKP
Protein: Signal recognition particle 43 kDa protein, chloroplastic (Chromo protein SRP43) (CpSRP43) (O22265)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the chloroplast signal recognition particle pathway. Required for post-translational targeting of proteins into the thylakoid membrane but seems to be dispensable for co-translational targeting with a translating ribosome present. May be able to function independently of cpFTSY and FFC/cpSRP54 in targeting LHCPs to the thylakoids. Acts as a highly specific chaperone for LHCPs, preventing aggregation and being able to dissolve aggregates.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:9878634}.
Interaction partners:
- Signal recognition particle subunit SRP54, chloroplastic
- Inner membrane protein ALBINO3
- Cell division protein FtsY homolog, chloroplastic
- Chlorophyll a-b binding protein 2, chloroplastic
- Chlorophyll a-b binding protein 1, chloroplastic
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein
- Chlorophyll a-b binding protein 3, chloroplastic
- Signal recognition particle 14 kDa protein
- Signal recognition particle 9 kDa protein
Sequence:
MQKVFLAMDTCALVIHQSLSRIKLSPPKSSSSSSSAFSPESLPIRRIELCFRGAICAAVQRNYEETTSSVEEAEEDDESSSSYGEVNKIIGSRTAGEGAMEYLIEWKDGHSPSWVPSSYIAADVVSEYETPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILKTTPKGNPMQFGRRIGLEKVINVLEGQVFEYAEVDEIVEKRGKGKDVEYLVRWKDGGDCEWVKGVHVAEDVAKDYEDGLEYAVAESVIGKRVGDDGKTIEYLVKWTDMSDATWEPQDNVDSTLVLLYQQQQPMNE
Protein: G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6) (O70293)
Organism: Mus musculus (Mouse)
Function: Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro) (By similarity).
Subcellular location: Membrane; Lipid-anchor.
Interaction partners:
- ARF GTPase-activating protein GIT1
- NADH-ubiquinone oxidoreductase chain 1
- Beta-arrestin-2
- Mu-type opioid receptor
- Beta-arrestin-1
- C-X-C chemokine receptor type 2
- ARF GTPase-activating protein GIT2
- C-X-C chemokine receptor type 1
- C-X-C chemokine receptor type 4
- Beta-2 adrenergic receptor
Sequence:
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL
Protein: Junctional adhesion molecule 2A (Jam2a) (Junctional adhesion molecule B) (JAM-B) (A0A0R4IGV4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Junctional adhesion protein that mediates heterotypic cell-cell interactions to regulate different cellular processes (By similarity). During myogenesis, it is involved in myocyte fusion through the binding of jam3b on neighboring myocytes.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P57087}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P57087}. Cell junction {ECO:0000250|UniProtKB:P57087}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q9JI59}.
Interaction partners:
- Junctional adhesion molecule 3B
- Protein myomaker
- Si:ch211-158d24.4
- Tight junction protein 1a
Sequence:
MLVCVSLLILIHSVPVSPVTVSSRNPKVEVHEFSDAELSCEFKTEKDTNPRIEWKRKDKEKDVSFVYYGERFVGPFQDRADIEGATVRLRRVTQADAGEYRCEVSAPSDSISLGETNVTLRVLVPPQTPSCDVPSSALTGSQVELRCRDRHSIPPAVYTWYKDNRALPIRHPNATYTVNEFTGVLIPQSHYNPGTVCQHCMYHPNYHIPNTQLTTTFQTHDLNVAAVVSAVVLVCVILFLCAFGVCLAHRQGYFSRHRGRSFWIPHCHGVTHISSQNLNPSEHTQHSGYSHPPKEPQDFKHTQSFML
Protein: N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2) (Q8JZV7)
Organism: Mus musculus (Mouse)
Function: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
Interaction partners:
- Glucosamine-6-phosphate deaminase 2
- Glucosamine-6-phosphate deaminase 1
- Glutamine--fructose-6-phosphate aminotransferase 1
- Phosphoacetylglucosamine mutase
- N-acetyl-D-glucosamine kinase
- Glutamine--fructose-6-phosphate aminotransferase 2
- Glucosamine 6-phosphate N-acetyltransferase
- Hexokinase-3
- Hexokinase-2
- Hexokinase-1
Sequence:
MRSGQCAAGAPVLQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGRILAPGFIDVQINGGFGVDFSKATEDVGSGVALVARRLLSHGVTSFCPTLVTSPPEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAYLRSFEANAFHDVLATYGPLDNVCIVTLAPELDRSHEVIQALTAQGIRVSLGHSVADLRAAEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDQLPPGHCIFYGMIADGIHTNPAALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYIAGTKTLGGSIAPMDVCVRHFLQATGCSVESALEAASLHPAQMLGLEKTKGSLDFGADADFVVLDDTLHVQATYISGELVWQAEEAGP