wanglab/gogpt-training-data huggingface dataset:
Protein: Oncoprotein MEQ (MEQ) (Q9DGW5)
Organism: Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1)
Function: Functions as a DNA-binding transcription factor. Promotes transformation, host cell growth, host cell-cycle progression through G1/S phase, and possesses antiapoptotic activity. Forms functional heterodimers with host JUN. These heterodimers bind with high affinity DNA sequences called MEQ-responsive elements MERE I (TGACA/GTCA), while MEQ homodimers bind a second type of sites termed MERE II (ACACA). Both homo and heterodimerization of MEQ are required for oncogenesis.
Subcellular location: Host nucleus, host nucleolus {ECO:0000269|PubMed:10196317, ECO:0000269|PubMed:9060682}. Note=Expressed in both the nucleus and the cytoplasm during the G1/S boundary and early S phase of host cell cycle.
Interaction partners:
Sequence:
MSQEPEPGAMPYSPADDPSPLDLSLGSTSRRKKRKSHDIPNSPSKHPFPDGLSEEEKQKLERRRKRNRDAARRRRRKQTDYVDKLHEACEELQRANEHLRKEIRDLRTECTSLRVQLACHEPVCPMAVPLTVTLGLLTTPHDPVPEPPICTPPPPSPDEPNAPHCSGSQPPICTPPPPDTEELCAQLCSTPPPPISTPHIIYAPGPSPLQPPICTPAPPDAEELCAQLCSTPPPPICTPHSLFCPPQPPSPEGIFPALCPVTEPCTPPSPGTVYAQLCPVGQVPLFTPSPPHPAPEPERLYARLTEDPEQDSLYSGQIYTQFPSDTQSTVWWFPGDGRP
Protein: Z band alternatively spliced PDZ-motif protein 66, isoform G (Q9VSN0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEYVQFKNGSPVYYKEQPDLNECIQYQPYRTTPLVLPGAKVKKDAPTTESYLRHYPNPAVRAHPGHDYHDSIMKQRVADTMLHKVVGSEADTGRVFHKQFNSPIGLYSNNNIEDTIRSTVPIFIDLSFLEQKRIILEQQKQKDQLAEQQRQQRQHQLQILYQQNK
Protein: Putative diacyglycerol O-acyltransferase Rv2285 (EC 2.3.1.20) (Putative triacylglycerol synthase Rv2285) (P9WKB5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis.
Interaction partners:
- Possible triacylglycerol synthase
- Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1
- Triacylglycerol lipase
- Diacylglycerol kinase
- Uncharacterized oxidoreductase Rv1543
- Probable enoyl-CoA hydratase EchA14
- Polyketide synthase Pks13
- Phenyloxazoline synthase MbtB
- Probable carboxylic ester hydrolase LipM
Sequence:
MKLLSPLDQMFARMEAPRTPMHIGAFAVFDLPKGAPRRFIRDLYEAISQLAFLPFPFDSVIAGGASMAYWRQVQPDPSYHVRLSALPYPGTGRDLGALVERLHSTPLDMAKPLWELHLIEGLTGRQFAMYFKAHHCAVDGLGGVNLIKSWLTTDPEAPPGSGKPEPFGDDYDLASVLAAATTKRAVEGVSAVSELAGRLSSMVLGANSSVRAALTTPRTPFNTRVNRHRRLAVQVLKLPRLKAVAHATDCTVNDVILASVGGACRRYLQELGDLPTNTLTASVPVGFERDADTVNAASGFVAPLGTSIEDPVARLTTISASTTRGKAELLAMSPNALQHYSVFGLLPIAVGQKTGALGVIPPLFNFTVSNVVLSKDPLYLSGAKLDVIVPMSFLCDGYGLNVTLVGYTDKVVLGFLGCRDTLPHLQRLAQYTGAAFEELETAALP
Protein: E3 SUMO-protein ligase MMS21 (EC 2.3.2.-) (E3 SUMO-protein transferase MMS21) (Methyl methanesulfonate-sensitivity protein 21) (Non-structural maintenance of chromosome element 2) (Non-SMC element 2) (P38632)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Acts as an E3 ligase mediating SUMO/Smt3 attachment to SMC5 and YKU70. Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
Subcellular location: Nucleus {ECO:0000269|PubMed:15738391}. Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Non-structural maintenance of chromosome element 3
- Structural maintenance of chromosomes protein 5
- Non-structural maintenance of chromosome element 4
- Structural maintenance of chromosomes protein 6
- Non-structural maintenance of chromosomes element 1
- Non-structural maintenance of chromosome element 5
- DNA repair protein KRE29
- SUMO-conjugating enzyme UBC9
- E3 SUMO-protein ligase SIZ2
- E3 SUMO-protein ligase SIZ1
Sequence:
MALNDNPIPKSVPLHPKSGKYFHNLHARDLSNIYQQCYKQIDETINQLVDSTSPSTIGIEEQVADITSTYKLLSTYESESNSFDEHIKDLKKNFKQSSDACPQIDLSTWDKYRTGELTAPKLSELYLNMPTPEPATMVNNTDTLKILKVLPYIWNDPTCVIPDLQNPADEDDLQIEGGKIELTCPITCKPYEAPLISRKCNHVFDRDGIQNYLQGYTTRDCPQAACSQVVSMRDFVRDPIMELRCKIAKMKESQEQDKRSSQAIDVL
Protein: CLAVATA3/ESR (CLE)-related protein 44 (Tracheary element differentiation inhibitory factor-like protein) (TDIF-like protein) [Cleaved into: CLE44p] (Q941C5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Extracellular signal peptide that regulates cell fate. May act with TDR as a ligand-receptor pair in a signal transduction pathway that represses tracheary element differentiation but promotes the formation of procambial cells adjacent to phloem cells in the veins. Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2.
Subcellular location: [CLE44p]: Secreted, extracellular space {ECO:0000269|PubMed:18812507}. Note=Probably secreted from the phloem cells and distributed in the procambial region. {ECO:0000269|PubMed:18812507}.
Interaction partners:
- Leucine-rich repeat receptor-like protein kinase TDR
- CLAVATA3/ESR
- WUSCHEL-related homeobox 4
- Somatic embryogenesis receptor kinase 2
- WUSCHEL-related homeobox 14
- Protein CLAVATA 3
- CLAVATA3/ESR
- CLAVATA3/ESR
- CLAVATA3/ESR
- CLAVATA3/ESR
Sequence:
MATTIDQTSIKSLHFHQVIRLIITIIFLAFLFLIGPTSSMNHHLHESSSKNTMAPSKRFLLQPSTPSSSTMKMRPTAHPRRSGTSSSSARKRRREFRAEAHEVPSGPNPISN
Protein: DNA-binding protein modulo (P13469)
Organism: Drosophila melanogaster (Fruit fly)
Function: Its capacity to bind DNA and protein(s), and its differential expression during development suggest a role in the regulation of gene expression during Drosophila development. It could, in interaction with other factors, be required for the translation of instructions provided by pattern forming genes and controls, via chromatin changes, the activity of genes critical for the process of morphogenesis of several embryonic territories.
Subcellular location: Nucleus.
Interaction partners:
- Andropin
- ATP-dependent RNA helicase DDX47
- Ribosome biogenesis protein BOP1 homolog
- Ribosomal RNA processing protein 1 homolog
- Nucleoplasmin-like protein
- Probable elongation factor 1-delta
- Nucleolar protein 58
- H/ACA ribonucleoprotein complex subunit 2
- LD11307p
- Pre-rRNA-processing protein TSR1 homolog
Sequence:
MAQKKAVTVKGKKATNGEEKPLAKRVTKSTKVQEEETVVPQSPSKKSRKQPVKEVPQFSEEDESDVEEQNDEQPGDDSDFETEEAAGLIDDEAEEDEEYNSDDEEDDDDDELEPGEVSKSEGADEVDESDDDEEAPVEKPVSKKSEKANSEKSEENRGIPKVKVGKIPLGTPKNQIVFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKSVLIAFDTSTGAEAVLQAKPKALTLGDNVLSVSQPRNKEENNERTVVVGLIGPNITKDDLKTFFEKVAPVEAVTISSNRLMPRAFVRLASVDDIPKALKLHSTELFSRFITVRRISQESISRTSELTLVVENVGKHESYSSDALEKIFKKFGDVEEIDVVCSKAVLAFVTFKQSDAATKALAQLDGKTVNKFEWKLHRFERSTSGRAILVTNLTSDATEADLRKVFNDSGEIESIIMLGQKAVVKFKDDEGFCKSFLANESIVNNAPIFIEPNSLLKHRLLKKRLAIGQTRAPRKFQKDTKPNFGKKPFNKRPAQENGGKSFVKRARF
Protein: IQ-domain 1 (F4J1A4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MVKKAKWLKNVKKAFSPDSKKLKHESVECQDSVISYPVLIATSRSSSPQFEVRVDEVNYEQKKNLYPPSSDSVTATVAHVLVDSPPSSPESVHQAIVVNRFAGKSKEEAAAILIQSTFRGHLARRESQVMRGQERLKLLMEGSVVQRQAAITLKCMQTLSRVQSQIRSRRIRMSEENQARHKQLLQKHAKELGGLKLFMRLFKFIVVSSDNGGNWNYSNQSKEQVEAGMLHKYEATMRRERALAYAFTHQQNLKSFSKTANPMFMDPSNPTWGWSWLERWMAGRPWESSEKEQNTTNNDNSSVKNSTNRNSQGGETAKSSNRNKLNSSTKPNTPSASSTATRNPRKKRPIPSSIKSKSSDDEAKSSERNRRPSIARPSVSDDETLSSSTARRSSNLIPTTKSARGKPKSQTSSRVAVTTSTTEESSILPEKAPAKKRLSTSASPAPKPRRSSAPPKVEKGVLKAERTP
Protein: non-specific protein-tyrosine kinase (EC 2.7.10.2) (A0A499FJ16)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00029433}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00029433}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00029433}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLEARPPRTQGSDAAGAAAGRGLRALLLSLTAAAGIWGSMGERSAYQRLAGGEEGPQRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDELYLGNPMDPPDLLSVELSTSRPPQHLGGVKREPPPRPPQPAFFTQKPTYDPVSEDQDPLSSDFKRLGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATARLPQRGCPGDGPEAGRPADKIQMVEQLFGLGLRPRGECHKVLEMFDWNLEQAGCHLLGSWGPAHHKR
Protein: ZIC family member 5 (Odd-paired homolog, Drosophila) (Zinc finger protein ZIC 5) (Zinc finger protein Zic5) (Q6VUB8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEPPLSKRNSAIRLADLASTQALPHQNMTGFPGIGGHHPHSHHAHLHPGEMGNDPGVALTPFGPEHMAQTNALKLSPSQPVQSHPEAQTAASFTSSQTTVGFPVAHPHTGYTTSRDFILRRELSASAMHALGDQHSSASSPHHHGMFISPTGAYGHAEGGAHPLFSGLHEQAAPGAHHHHHALNGQMRLGLPGDIYGRPEHFGHRPEHYGSSSLHSYNSMNLNVNLATAPHGATGAFLRYMRQPIKQELICKWIDQEQTAKKPCSKTFSTMHELVNHVTVEHVGGPEQSTHVCFWEECPREGKAFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYFCKVRGCDKSYTHPSSLRKHMKVHCKSPPPPSANTGSSYHPSSTTIGDALSPNLDPHRNRSSNLSPQVTNLNEWYVCQGSAGPNNLHTPSSDVPTSESDDEDSFRHTDPRAML
Protein: Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Q7TNS7)
Organism: Mus musculus (Mouse)
Function: Probable cation channel with high affinity for sodium.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P78348}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Acid-sensing ion channel 1
Sequence:
MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGPAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAASLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRAESELREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEISMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQQAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLRTSTGGISTLGLQELKEQSPCPSRGRAEGGGASSLLPNHHHPHGPPGSLFEDFAC
Protein: Protein RecA (Recombinase A) (Q1DCH8)
Organism: Myxococcus xanthus (strain DK1622)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00268}.
Interaction partners:
- DNA topoisomerase III/ATP-dependent DNA helicase, RecQ family
- LexA repressor
- Protein RecA
- DNA polymerase I
- Helicase, DEAD/DEAH family
- Protein RecA
- Regulatory protein RecX
- DNA topoisomerase 1
- Regulatory protein RecX
- DNA repair protein RecN
Sequence:
MAVNQEKEKAIELAMSAVERQFGKGSIMRLGNDEPMMRDVQAIPTGSISLDIALGVGGVPKGRIIEIFGPESSGKTTLCLHIVAEAQKRGGICGYVDAEHALDVGYARKLGVRTDDLLLSQPDTGEQALEIAEMLVRSGAIDVLVVDSVAALVPKAELEGEMGDAHMGVQARLMSQALRKLTGTIAKSQTCVIFINQIRMKIGVMFGNPETTTGGNALKFYASQRLDIRRIGAIKNGDNVVGSRTRVKVVKNKVAPPFKEVEFDIMYGTGISREGDLIDLASNENIVEKSGSWFSFNGERIGQGRENVKEYLREHPEIAKDIEGRVLEKYGIGKSGAPVAAAPDESAPAEGGSEKRGRVKAVK
Protein: Large ribosomal subunit protein uL15 (60S ribosomal protein L27a) (P18445)
Organism: Rattus norvegicus (Rat)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P46776}.
Interaction partners:
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein eL18
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL1
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL15
Sequence:
MPSRLRKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGMHHHRINFDKYHPGYFGKVGMRHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKNGVAPIIDVVRSGYYKVLGKGKLPKQPVIVKAKFFSRRAEEKIKGVGGACVLVA
Protein: Adventurous-gliding motility protein Z (Q1D823)
Organism: Myxococcus xanthus (strain DK1622)
Function: Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17289998}. Note=In motile cells, localizes in ordered clusters spanning the cell length. In stalled cells, localizes at the leading cell pole.
Interaction partners:
- Mutual gliding-motility protein MglA
- Adventurous gliding motility protein AgmX
- Adventurous gliding motility protein AgmK
- DEAD/DEAH box helicase
- AMIN domain-containing protein
- Tetratricopeptide repeat protein
- Tetratricopeptide repeat protein
- Frizzy aggregation protein FrzCD
- Lipoprotein
- Tetratricopeptide repeat protein
Sequence:
MERRVLIVESEHDFALSMATVLKGAGYQTALAETAADAQRELEKRRPDLVVLRAELKDQSGFVLCGNIKKGKWGQNLKVLLLSSESGVDGLAQHRQTPQAADGYLAIPFEMGELAALSHGIVPPGTDDTGASLDAALNGTREAPPPMPPSLKAAAGGPPKLPKRERRSAMTEEDRAFLDRTFQSIADRKAELLAESRQLKRPPPRRELMGTPEGKIQILRDELKTREAQLARLSEIWNVRERELLSGEDRIHEKDVELQGLKMQVDDLLRRFNEAQQATIQKEREHGATVDDLLLQKFSAEKDLIEVVASKEKDINLLRREVSRAEEELSRRAGELEHGRNEYDKLEKHLGVVTLEFEVKEQKLQDTVLANEGEIARLTKRGDDFEAELNRTISERDQRFAELDGEIQALQERLQQTEQERDTTVRGLEARAARAEEHGTQADAEIHRLNAERDALEAKLSQQVADLEADLARTMGERDQLRLDKDAQEAELTQRIEERDAKLGTLERELSETIARNEHTEAELNANIQQQLERIGELEGEVEAVKTHLEDRENELTAELQALGQAKDELETDLNDRLQALSQAKDALEADLSRQLEELRSAKAELEADLTGQIQALTSQLEETQRQLDDSQRTGEQLSARVAQLEDTVSQRESTIESLQGDVAARDQRISELSGDLEATSQTLAQTQQTLAQTEQQLADTQNTLASTEGALAETRGELDATSQTLQQTQQTLAQTEGALAETRGELDATSQTLAQTQQTLAQTEQQLADTQNTLASTEGTLAETRGELEATSQTLQQTHAALEDTRGALQETSDTLAHTTRERDQRIAELADLGAAKDALEQELTGQIGHLRSELSETQGNYEAERAAHEKLAAESSAHIGDLTSERDGLRSELEATSQTLEQTHGQLAATRDALAREQHAHQESRKAAASTQTTLEGQLAEARAHGEDLGEHLTLTKHELGTRVAELTQLTATLAQTENTRAHLEERLHTLTEESQRREELLQNDLTQKGTELSDTLRKLTHVTQEKMRQAEVLNREVATRTEQLKAMEAKLQTQATEARRQAEGLGQQITGLNEQLEQGRKALAGREDQLRAAGAAQQKLTAERDGLAGQLQQAEARLQQQAQQANQERADAKRAADELAAKLAKTEQRITQFAQDAQTQATEADARAKDLQGQLSARAKKIQDLELAVENAQGAKSRAEKELNAKVAAAESKAHEASTRLAAAQKERKDLEARHAKEQEDLAAKQKAELERRDAIKAQEVARLQQSVQEKSKALKVAELELARYKSKSATTATPAKAAAKPAAAEDDELAVRTQLNQVIAPAAAAQAPAPAKKPAAKPAAQAPAKKAPAPAPAPPAALSDESEPTDRTLVIQLPTAKEDDDWTALVDELDK
Protein: Chromobox protein homolog 8b (Zgc:111978) (Q502N4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MELSAVGERVFAAESIIKRRIRRGHMEYLVKWKGWSPKYSTWEPEENILDPRLFVAFEEREREREIFGPKKRGPKLKTFLLKAQAKEKAKSYEFRNDSSRGIHVTYSSPEPVVAPRAREGLRAVVPTIFPPSTVNRGESVRLQSPEPREHHSPHSPRPTDEFSLTPKKRGRKPKLRFTDGYTSNLHPEHVKRAADETMASIPSKMAKLGLGEDDERCPDISGRLKISHKDLDATCSHKQSNVIPSRSTLHISPQWSLHSSRMEAGLLGHRTNPQSNHFHQKHLKHYSKKRTLEHGDSTSRQPSLIAKIPVSHIFREPGVEDAWRPSVINVEKVIVTDVTTNFLTVTIKESNTDEGFFKDKT
Protein: Seripauperin-21 (P0CE86)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Putative uncharacterized protein YOR392W
- Uncharacterized membrane protein YOR365C
Sequence:
MTNEGIGINRDTSTICLREYVFIHFFPVKLISALTNKTNTMVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVSDIRAHLAQYYLFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYSTRLRPAISSALSKDGIYTAIPK
Protein: Ran-binding proteins 9/10 homolog (Ran-binding protein M) (Q4Z8K6)
Organism: Drosophila melanogaster (Fruit fly)
Function: May be involved in JAK/STAT signaling. Isoform D is required for the proper arrangement of niche cells and is autonomously required for proper niche cell size, isoform C negatively regulates the adhesive properties of the niche. The germline stem cell (GSC) niche in ovaries is made up of two somatic cell types: 8-9 cells in a single-filed array make up the terminal filament (TF), and a tight cluster of 5 or 6 cap cells (CpC). Regulating the size and adhesive properties of the CpCs is an important component of the mechanism that controls their capacity to support stem cells, isoform C and isoform D are important factors in mediating this regulation. In contrast, isoform C acts as a positive regulator of cell adhesion in follicle cell epithelium.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18762575}. Membrane {ECO:0000269|PubMed:18762575}. Nucleus {ECO:0000269|PubMed:18762575}. Note=Distribution varies depending on cell type and developmental stage. At late embryogenesis expression is enriched in the nuclei of follicle cells and germline cells and at the nurse cell membranes. In pupal ovaries, expression is seen in niche cells at the cell periphery. In adult ovaries expression is in the nuclei and cytoplasm of the CpCs and TF cells of the niche.
Interaction partners:
- WD repeat-containing protein 26 homolog
- GH10162p
- FI21269p1
- E3 ubiquitin-protein transferase MAEA
- Houki
- Ubiquitin-conjugating enzyme E2 H
- RH01588p
- Fructose-1,6-bisphosphatase isozyme 2
- Protein yippee-like
- Protein yippee
Sequence:
MENVEEAPPLSSESNSNSNNSSASSSSHQLSQSGAMGAEIAPSTSRSHSHSPTPSPPVPASSHDQPHPDHPSPPLNASETEARENSPHDHSPTPTFHQTAPPPTTSSTAPQRDEREQQQQQEAPPLQQDQQENSPAQDQELHPLLDQQNQEYPAVHQDQQAEQNQELHHIEGLIRHRESQNPEEHPPQASLENRETLGREDTNQEPDEPQVRDPEIEPEAEPPPPLLLEDLDEQDSGSQDLNEQQPPLIIDANAIAETIDANAVERIDDYEDDDEEVDEEEEVVEDRVDRAGEVASVSGAQRLHSVAVLPRYSSASRAPRSSNNNNNNISNHNNNNNNSNSNSLSRRTRHFYSNNGSHFSNDMFPSHNPRSSTQTSSPRVGGRRHHSTPAASSNSPQHQGVDPLRLLYPNVNESETPLPRCWSPHDKCLSIGLSQNNLRVTYKGVGKQHSDAASVRTAYPIPSSCGLYYFEVRIISKGRNGYMGIGLTAQQFRMNRLPGWDKQSYGYHGDDGNSFSSSGNGQTYGPTFTTGDVIGCCVNFVNNTCFYTKNGVDLGIAFRDLPTKLYPTVGLQTPGEEVDANFGQEPFKFDKIVDMMKEMRSNVLRKIDRYPHLLETPENLMNRLVSTYLVHNAFSKTAEAFNGYTNQTFNEDLASIKTRQKIIKLILTGKMSQAIEHTLRSFPGLLENNKNLWFALKCRQFIEMINGADIENVNNKVTATTQTMPTNQTSVIQSTKTFKHSKSGSGNGNVNINQTQQQNNTAIPAVIKPQGGDRPDIKNMLVDDNSNKCVEHDSNSMDVEMEPCQSHSNGGDSSSNGNASAVRNSLDAIDEEMDVDVSPSSRNCGRVIEKILEFGKELSSMGQQLEKENLMTEEERQMLEDAFSLIAYSNPWSSPLGWLLCPSRRESVSTTLNSAILESLNFERRPPLEYLVAHASELIKVIGQHSLGEDAFITIDDVFPQN
Protein: Warthog protein 1 [Cleaved into: Warthog protein 1 N-product; Warthog protein 1 C-product] (Q94128)
Organism: Caenorhabditis elegans
Function: Intercellular signal essential for a variety of patterning events during development.
Subcellular location: [Warthog protein 1]: Secreted {ECO:0000250}. Cell surface {ECO:0000250}. Note=Also secreted in either cleaved or uncleaved form to mediate signaling to other cells. {ECO:0000250}.; SUBCELLULAR LOCATION: [Warthog protein 1 N-product]: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}.; SUBCELLULAR LOCATION: [Warthog protein 1 C-product]: Secreted, extracellular space {ECO:0000250}. Note=Also secreted in either cleaved or uncleaved form to mediate signaling to other cells. {ECO:0000250}.
Interaction partners:
- Apple domain-containing protein
- Fungal lipase-like domain-containing protein
- SUppressor of Pkc-3
- LiPocalin-Related protein
- Ground-like domain-containing protein
- WaRThog
- Cuticle collagen dpy-2
- Secreted protein
- C6 domain-containing protein
- Amine oxidase domain-containing protein
Sequence:
MMVMNPLTATFLAALIGTAASASCGSSGIPFRFEVLPSGQPVLGCGSPTCFGAENGGRDLRHDSSFMAGADGDDGFFRDGDLARVRVRDPDAPAQMANCPREFSSSSCSNPMTWVGGFKASDNGDLSLQCCHYEGLRFAQEVGRPVVHPGEVYSGGEVLRDGRQTGFDAISNVRKITSGDGTVAYEVTVTRMNCLPNPGEESNEVSFDIQRDIGRILDKVGETAASGVQTNHIEADQRLSPSTDVQSDSYVSPTEADPQEPVEQFVQVGEQVVPVTSAGYYYPVASGVPACFTGNSKVMTPAGEKSMADLSVGDMVMTYEYGKMTYTRVASWLHRLPDTKAAFIKLTTEQGAIIDMTPQHFIYKANCVTEEMELVYAEDMTIGDCLMVKENEKLVMTTISEKSTFYETGVYAPMTETGDLIVDDVYASCHNVVKANTLSHTFLNFATSVQQKMRSVLGSLEETGHLPATSEFFLNIIDVLLPHKY
Protein: At5g48335 (Q6AWV7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MQNPNSSSSLVDSTSAPKRYTPPNQRNRSSNRRRSRGSFHSNEGESSQSVAVGFQRENSSPKIISVEGCSRSEAFQLLSDRWTAAMHLYNDPSVDLSERPMMYYGGDVWGKLPH
Protein: Folate-biopterin transporter (Q55721)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Mediates folate monoglutamate transport involved in tetrahydrofolate biosynthesis. It also mediates transport of antifolates, such as methotrexate and aminopterin.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Ycf21 gene product
- Hydrogenase component
- Slr1699 protein
- Slr0845 protein
- Fibrillin
- Slr1676 protein
- Sll1071 protein
Sequence:
MLVAMSMTPIAILFSTPLKRFLREKVLLGNAPSWELLAILSIYFVQGVLGLSRLAVSFFLKDELGLSPAAMGALIGLGAAPWILKPVLGLMSDTVPLFGYRRRSYLWLSGLMGSAGWLLFAAWVSSGTQAGLVLLFTSLSVAIGDVIVDSLVVERAQRESLAQVGSLQSLTWGAAAVGGIITAYASGALLEWFSTRTVFAITAIFPLLTVGAAFLISEVSTAEEEEKPQPKAQIKLVWQAVRQKTILLPTLFIFFWQATPSAESAFFYFTTNELGFEPKFLGRVRLVTSVAGLIGVGLYQRFLKTLPFRVIMGWSTVISSLLGLTTLILITHANRAMGIDDHWFSLGDSIILTVTGQIAFMPVLVLAARLCPPGIEATLFALLMSVMNLAGVLSFEVGSLLTHWLGVTETQFDNLALLVIITNLSTLLPLPFLGLLPAGDPQVKDKTEKEDNPDDPGDRLVLPPAEVFEHHTVGSLSDQNFLPEFFPEKSSSRP
Protein: Uncharacterized protein (Q57X12)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMYRWSPPSLSKKVKGDTFLSSLAQRVDSVAATSSSRQEPGGTLSNLRLGLRGSSTMCRSAFSLHSNQSLVGNRIFECPNKHIFLDTNASYCHLCREPLGVSSFTHLSDREHHNVQLFLFLSAAFPRGTLRDATDLSTTFAKTTWRAIGRGDNTAGESILYHPDEVMDDAARFCPRLLAAVKGGYAHTEQEALRRASLQSMLILLSSGSITSDGATRREPAVLGVFHGDVLPELAHSGERLFKGEVSRLIVEWFPALSAGVGTQIAHKCWGRSNLESVFDALQLQTLINQRCNRAAVRGSGSGWKSTLMKGLTTKTEKATFMRLLMWELTTRNEDVGGDTNDGVSLNKVDRLLLELTRKRLAFEMVYLQSLKYMHLADALLQEMSYPSLEDLVLIGAA
Protein: U5 small nuclear ribonucleoprotein component, putative (Q381P2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA helicase
- Small nuclear ribonucleoprotein SmD1
- Pre-mRNA-processing factor 19
- Uncharacterized protein
- Uncharacterized protein
- Pre-mRNA-splicing factor U5-Cwc21
- Uncharacterized protein
- Small nuclear ribonucleoprotein E
- PRP8 protein homologue
- Small nuclear ribonucleoprotein Sm D2
Sequence:
MNFGYDEEGNRVPSDQSGCGDSTSREYDGTHEVRSTSDDNDNDSSGSAGSGTESNRGSDGSDSVEHERRRHDDDTTSGSSGDFGDDVELVIGEVANQSIDEPLVAGRDVASSTMKNRRDAAGGKFLLEDRLVHPLLIGEVVSKEPSTRDFLDLLRGVPSRQRIVAVAGHLHHGKTSLLSLLLGGRAYRQREDEVERGISVKSSVVTEVVAGAHYEQTSHLMTFVDTPGHPDFAAETAAALRLADAVLFCVDAAESLTSNGARLLRQVVLQEGIPIVLVITKIDRLIMDLKLPPLDAYRKLRMVVDAVNNEISSFGSGCSPFLVSPLNGTVCFASSNIGCFFTTETFALKYSSKYPSVDAIALSQQLWGQVTFEEGRFVRITNFRQKPSFVTLVLEPLYKVVAHSLTGKGSQVLSNKLNPLPRGPISAVREAVQLFCGDPALEGIDALLNVLPATDKRSAWLKTQYRLNVEEEDSAAAIAPIIRSQNNGEENFAVVRVLHGVLKRGVKVVVVDEHSSDAEPFYTFTVKELLLKMLDGFVDVDCAYAGQVVLVTGFDTRAGSHLVMVGGVAATSLLWEEENTIDSARESGASWLDEVRVLPLKCGKPFVHVGVELKNPAKANQLQQSLQILIRTTPGLDAHKEETGEFTISGYGELHLDTALHELRCALCKGVKLGISPPFVSFSETVLEKDGALAVTSSNWAHIGFTAGSLPTKLTEQIENEQINLFPSPGTDSVVKLWTTLQQHDMDALDARNIIATGPHTTKGPSVLINDTLDEEHEEFERLTEQRLQAITAGFRSAVAAGPLIGDVVRGAALRLIFADLEPDARDAAIMAGARTAAKQALLGAHPQLLEPVLKVDIMCPPGSVEKIAEVLQMRRGSIVSEEPIAATTFVCVRALVPAIDSFGLETQLRVVTLGEALPLFAFDSWDTVPGDPFDTTVHIGPLQPARGYQLARDFTLKTRFRKGLPPLLAEFQM