wanglab/gogpt-training-data huggingface dataset:
Protein: E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rab7-interacting RING finger protein) (Rabring 7) (Zinc finger protein 364) (Q9D0C1)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12972561}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:36281581}. Nucleus {ECO:0000250|UniProtKB:Q9Y4L5}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9Y4L5}. Golgi apparatus {ECO:0000250|UniProtKB:Q9Y4L5}. Note=The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes. {ECO:0000269|PubMed:12972561}.
Interaction partners:
- Large proline-rich protein BAG6
Sequence:
MAEASAAGADAGSAVAAHRFFCHFCKGEVNPKLPEYICPRCDSGFIEEVTDDSSFLGGGGSRTDNSTATHFAELWDHLDHTMFLQDFRPFLSSNPLDQDNRANERGHQTHTDFWGPSRPPRLPMTRRYRSRGSTRPDRSPAIEGIIQQIFAGFFANSAIPGSPHPFSWSGMLHSNPGDYAWGQTGLDAIVTQLLGQLENTGPPPADKEKITSLPTVTVTQEQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNGEDSTRQTQSSEASASNRFSNDSQLHDRWTF
Protein: RNA-editing complex protein nuclease, putative KREPB1 (Q4GZ50)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- RNA-editing ligase 1, mitochondrial
Sequence:
MGLHWPLARSSNWCHMRALSNEHLRRRVGAAVRSIASTAPCFALERVEVAHSHAYSRRGVTVGFTSSSSPSGKTGSGGLSPASQSLHSSSSFDASNGDVLANYVNFVADDATGPAATKENGAQPMRSLRSASAVENLLFTDAAKNYCRLCMEEVQVTPKAHISTPYRGSHTNHTCREVVLDSLALLAIRGYPIDDVYFVWADTLYQSSVFQRIPELVSPRWTVDKRSEVLAKILFMLKDMGVIDISLAAQAPDLFDNTAQQVHHRRRVAFERLEYIGDNSWGNHLSNRMMLLFPDRQWTYSQNAYTFNCFRDACEMNVTLEFMFDTLRVGELLPPGVREKLGTGKIKADVVEAVIGELHVTLWGLEPQLYDSVCFVEINGVGEARLAALVQHCLTEIYDLIVLSYVQELSGSAVPLAKQIAADRIWNSVYPPVRKAKDRAPGGRKSRSTVVNVVGVGEVRQLPSLPSLFPVASKRPTRAPHPLRRLRKLGEIPEETVCAGTNKDVFVHLIESYERLDMLDDSLLPTLNMRRLQDVQFSKLKRQLVPSLSPAALEELHNCKELDAESVTPHKVGDKEVATDERVLDLEEVYFRDKYFDLFPTPLPNEVVTKEGDCDKRQSGASTSRAVIISLPRGFDGGRPCNRAQLHMARNTIYPSLTERPAHSPTAGITKGDRVCLFSLSVYVPPDTKRPSAGVVTDKNLHFGEFAFHGVRIKGIECASEPECISRRSNAPGSDVGTSLNRSSWKEGGDNSCGTLTVEDGTGENSVVGEDGDTGVNGGEGKAEDATGKHLLRAKWCRENPFFPRASLPLLGISVGA
Protein: Nicotinamide riboside kinase (NRK) (NmR-K) (EC 2.7.1.22) (Nicotinic acid riboside kinase) (EC 2.7.1.173) (Ribosylnicotinamide kinase) (RNK) (Ribosylnicotinic acid kinase) (P53915)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN).
Interaction partners:
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
- Uridine nucleosidase
- Nicotinate phosphoribosyltransferase
- Nicotinate-nucleotide pyrophosphorylase [carboxylating]
- Purine nucleoside phosphorylase
- NAD-capped RNA hydrolase NPY1
- Nicotinamide mononucleotide adenylyltransferase
- Glutamine-dependent NAD
- Nicotinamidase
Sequence:
MTSKKVILVALSGCSSSGKTTIAKLTASLFTKATLIHEDDFYKHDNEVPVDAKYNIQNWDSPEALDFKLFGKELDVIKQTGKIATKLIHNNNVDDPFTKFHIDRQVWDELKAKYDSINDDKYEVVIVDGFMIFNNTGISKKFDLKILVRAPYEVLKKRRASRKGYQTLDSFWVDPPYYFDEFVYESYRANHAQLFVNGDVEGLLDPRKSKNIKEFINDDDTPIAKPLSWVCQEILKLCKD
Protein: T. brucei spp.-specific protein (Q38AX9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MARYIYYIMLYYLRFLHQQLSPLLCTRGGGALLPGIGWSNELGSAIPLGYLEVPRHYVIEGVLWCCGPLPLLVERMNPSSGALRSLLSLPSGVISSDIYHTVIMVSACVKKAYRFYCYVCLRFCFTALRAV
Protein: Major DNA-binding protein (P09246)
Organism: Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
Function: Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA.
Subcellular location: Host nucleus {ECO:0000255|HAMAP-Rule:MF_04007}. Note=In the absence of DNA replication, found in the nuclear framework-associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments). {ECO:0000255|HAMAP-Rule:MF_04007}.
Interaction partners:
Sequence:
MENTQKTVTVPTGPLGYVYACRVEDLDLEEISFLAARSTDSDLALLPLMRNLTVEKTFTSSLAVVSGARTTGLAGAGITLKLTTSHFYPSVFVFHGGKHVLPSSAAPNLTRACNAARERFGFSRCQGPPVDGAVETTGAEICTRLGLEPENTILYLVVTALFKEAVFMCNVFLHYGGLDIVHINHGDVIRIPLFPVQLFMPDVNRLVPDPFNTHHRSIGEGFVYPTPFYNTGLCHLIHDCVIAPMAVALRVRNVTAVARGAAHLAFDENHEGAVLPPDITYTYFQSSSSGTTTARGARRNDVNSTSKPSPSGGFERRLASIMAADTALHAEVIFNTGIYEETPTDIKEWPMFIGMEGTLPRLNALGSYTARVAGVIGAMVFSPNSALYLTEVEDSGMTEAKDGGPGPSFNRFYQFAGPHLAANPQTDRDGHVLSSQSTGSSNTEFSVDYLALICGFGAPLLARLLFYLERCDAGAFTGGHGDALKYVTGTFDSEIPCSLCEKHTRPVCAHTTVHRLRQRMPRFGQATRQPIGVFGTMNSQYSDCDPLGNYAPYLILRKPGDQTEAAKATMQDTYRATLERLFIDLEQERLLDRGAPCSSEGLSSVIVDHPTFRRILDTLRARIEQTTTQFMKVLVETRDYKIREGLSEATHSMALTFDPYSGAFCPITNFLVKRTHLAVVQDLALSQCHCVFYGQQVEGRNFRNQFQPVLRRRFVDLFNGGFISTRSITVTLSEGPVSAPNPTLGQDAPAGRTFDGDLARVSVEVIRDIRVKNRVVFSGNCTNLSEAARARLVGLASAYQRQEKRVDMLHGALGFLLKQFHGLLFPRGMPPNSKSPNPQWFWTLLQRNQMPADKLTHEEITTIAAVKRFTEEYAAINFINLPPTCIGELAQFYMANLILKYCDHSQYLINTLTSIITGARRPRDPSSVLHWIRKDVTSAADIETQAKALLEKTENLPELWTTAFTSTHLVRAAMNQRPMVVLGISISKYHGAAGNNRVFQAGNWSGLNGGKNVCPLFTFDRTRRFIIACPRGGFICPVTGPSSGNRETTLSDQVRGIIVSGGAMVQLAIYATVVRAVGARAQHMAFDDWLSLTDDEFLARDLEELHDQIIQTLETPWTVEGALEAVKILDEKTTAGDGETPTNLAFNFDSCEPSHDTTSNVLNISGSNISGSTVPGLKRPPEDDELFDLSGIPIKHGNITMEMI
Protein: Robo2 (Roundabout homolog 2 precursor) (Roundabout2) (Q90Z70)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MGPLTHLLLCGLVYFNQVDGSRLRQEDSPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGAYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECVPPRGHPEPTIYWKKDKVRIDEKDDRIKIRGGKLMISNTRKSDAGMYICVGTNMVGERDSETAQVTVFERPTFLRRPTNQVVLEEEAVEFRCQVQGDPQPSIRWKKDDVEIPRGRYDMKFDKDDFTLRIKKATASDEGTFTCVAENRVGKMEASATLTVRARPVAAPQFVIRPRDQIVAQGRTASFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRFSVSPSGDLTITAVQRADAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIIRQGPANQTLGVDSVALLRCHASGEPVPTISWLKDGVSLLGKDPRMSLQDLGSLQIKGLRLSDSGIYTCVAASSSGETSWSAFLEVKEAGSLVVVKDRDENELPGPPSKPQVTDVTKNSVSLSWQPGLPGASAISTYVIEAFSQSVSNSWQTVADHVKTTQYTIKGLRPNTIYLFMVRAVNVQGLSDPSPMSEPVRTQDISPPAQGGDHRHVQKELGEVIVRLHNPVVLSPTTIQVTWTVDRQSQFIQGYRVLYRQMSGLSSPGAWQTQDVKVPSERSMVLSALKKGIVYEIKVRPYFNEFQGMDSESRTARTTEEAPSAPPQQVTVLTVGNQNSTSISISWDPPPAEHQNGIIQEYKIWCLGNETRFHVNKTVDAAIRSVVVGGLQAGVQYRVEVAASTSAGVGVKSEPQTIIIGKDFRDVMISRNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVQSFTFTPAVTFQRVDGGLMSNGSRPGLLNASDSGYPWLADSWPPSLPVNSGSGGPNDLSFGRGDVMPSAQADKTGTMLSDGAIYSSIDFTTKGGFGSPSPASQATPYATTQILHSNSIHELAVDLPEAQWKTSLQAKQEMASLGYSLPDKNSCNNTLLFIPDYRLADGLSNRMPHNQSQDFSTTSSHNSSDRSNSLSGGKGGKKKKTKANVKPTKMNGSNWANVPLPPPPIHPLPGTEMDHYASEHHDGGGYDSDGWGPPLPVQTYLHQGLEDELEEEEERVPTPPIRGVASSPAAVSFGKQSTATLSPSPREEMQPMLQAHLDELTRAYQLDMAKQTWHMQGGPYPPQAPAPPVGYISSTLVSDIETDLPDEDDDDEEDEGYEMSPPIRGTEHTPGSSMDNLDSSVTDKGLPHRPRPASPFSTDGSTVGTHSLGHQRAARPTRKHKGPGTVPNRRDASADDLPPPPEPPPCQTARIPGSRNVPHPCDRKASSLERQPMMGLEEMRSSLDRQARTSLDRHQQVQDRLGSIERGDESRRGQKNGPFSEEALLPYNKPSFPSPGGHSSSGTASSKGSTGPRKGEGTRGQHQRSTTEQGESSYMGTNAQFSGEL
Protein: Polyhomeotic-proximal chromatin protein (P39769)
Organism: Drosophila melanogaster (Fruit fly)
Function: Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility. Plays a role in regulating the expression of other pair-rule genes such as eve, ftz, and H.
Subcellular location: Nucleus.
Interaction partners:
- Polycomb group protein Psc
- E3 ubiquitin-protein ligase RING1
- Polycomb protein Scm
- Polycomb group protein Pc
- Polycomb protein esc
- Polycomb protein PHO
- Histone-lysine N-methyltransferase E
- Polycomb group protein Asx
- Polyhomeotic distal, isoform A
- Polycomb protein esc
Sequence:
MDRRALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVISPQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPPSLTPTTNPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKRKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ
Protein: Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (A0A0C4DG85)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF
Protein: DUF4130 domain-containing protein (Q9N5I0)
Organism: Caenorhabditis elegans
Interaction partners:
- Anoctamin
Sequence:
MYEDLYFWRKNGRPDIEKDHDFNAGCHMKMRYIETNLVLLKTYHMDFGEGQCSKKRQEELDRTVFSQDIQPYVQYSLNKKKRWEVEAAVKMLGELQKMYNDMDVVVLERIDFRGAPFFTGLRFPDNYFEKFRIQKMHKILDDKYYQCTAVDSVHGQKFNDIQFKNRSLNKSKDLEAETMTSKIAGRPIVAYHLIKPHQIYEKKVAKYFNPCSTKKKNWYYSELYSVDWYQLITEDTYEAITYDALEDHEWDELHEWEEEEDTGSISVAVSEKCYNLEDHLVDKYVMVKRKKA
Protein: Interferon regulatory factor (Q6TGZ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR038196}.
Interaction partners:
Sequence:
MPVSRMRMRPWLESRIDSNTINGLMWVNKEEKMFSIPWKHAARHGWEVDKDACLFKQWAIHTGKYKEGVTQPDPKTWKANFRCAMNSLPDIEEVKDKSINKGCGAVRVYRMLPAVSKKIKRSKSRDSRRRMKGLSQKVKLEDMSSEDTSAEMTQENTIDSTQSTPHTSSPTVGYEVEIGPDSTCNDIYSRFQVSPVHSTDLEDSEAILELTRQLERDSSQWLQNFGKGFLANEVCTTESLSPESQWSVSSGEELELRLYTELTPDLRSDSYTYTELWNSSSMPQSIC
Protein: Regulatory protein PcrH (Q9I325)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Translocator protein PopB
- Translocator outer membrane protein PopD
- Type III secretion protein PcrV
- Type III secretion outer membrane protein PopN
- Regulator in type III secretion
- Translocation protein in type III secretion
- Lipoprotein
- Type III secretory apparatus protein PcrD
- Type 3 secretion system secretin
- Type III secretion chaperone SycN
Sequence:
MNQPTPSDTDQQQALEAFLRDGGTLAMLRGLSEDTLEQLYALGFNQYQAGKWDDAQKIFQALCMLDHYDARYFLGLGACRQSLGLYEQALQSYSYGALMDINEPRFPFHAAECHLQLGDLDGAESGFYSARALAAAQPAHEALAARAGAMLEAVTARKDRAYESDNA
Protein: 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic (EC 2.4.1.25) (Amylomaltase) (Disproportionating enzyme) (D-enzyme) (Protein DISPROPORTIONATING ENZYME 1) (Q9LV91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Chloroplastic alpha-glucanotransferase involved in maltotriose metabolism. Probably uses maltotriose as substrate to transfer a maltosyl unit from one molecule to another, resulting in glucose and maltopentaose. The latter can then be further metabolized to maltose and maltotriose by beta-amylase. Required for normal starch degradation in leaves.
Subcellular location: Plastid, chloroplast. Plastid, amyloplast {ECO:0000305}.
Interaction partners:
- Alpha-glucan phosphorylase 1
- Alpha-glucan phosphorylase 2, cytosolic
- Isoamylase 3, chloroplastic
- Isoamylase 1, chloroplastic
- Alpha-amylase 3, chloroplastic
- 1,4-alpha-glucan-branching enzyme 2-1, chloroplastic/amyloplastic
- Isoamylase 2, chloroplastic
- 1,4-alpha-glucan-branching enzyme 2-2, chloroplastic/amyloplastic
- 1,4-alpha-glucan-branching enzyme 3, chloroplastic/amyloplastic
- Alpha-amylase 1
Sequence:
MSILLRPSSSPSLCSSLKLFRLSSPDSLIDAAVLRNRTKPSQSFRMEVVSSNSTCLSSISVGEDFPSEYEQWLPVPDPESRRRAGVLLHPTSFRGPHGIGDLGEEAFRFIDWLHSTGCSVWQVLPLVPPDEGGSPYAGQDANCGNTLLISLDELVKDGLLIKDELPQPIDADSVNYQTANKLKSPLITKAAKRLIDGNGELKSKLLDFRNDPSISCWLEDAAYFAAIDNTLNAYSWFEWPEPLKNRHLSALEAIYESQKEFIDLFIAKQFLFQRQWQKVREYARRQGVDIMGDMPIYVGYHSADVWANKKHFLLNKKGFPLLVSGVPPDLFSETGQLWGSPLYDWKAMESDQYSWWVNRIRRAQDLYDECRIDHFRGFAGFWAVPSEAKVAMVGRWKVGPGKSLFDAISKGVGKIKIIAEDLGVITKDVVELRKSIGAPGMAVLQFAFGGGADNPHLPHNHEVNQVVYSGTHDNDTIRGWWDTLDQEEKSKAMKYLSIAGEDDISWSVIQAAFSSTAQTAIIPMQDILGLGSSARMNTPATEVGNWGWRIPSSTSFDNLETESDRLRDLLSLYGRL
Protein: Apyrase GS50 (Q9FVC3)
Organism: Glycine soja (Wild soybean)
Interaction partners:
Sequence:
MSKDYLIILSLLLSTVLAAASSSSSSSSLYLGKGFSHRKLSPSYHIHKTIDESYAVIFDAGSTGSRVHVYRFNQQLDLLRIGQDLELFVKTMPGLSAYAENPQDAAESLIPLLEEAEAAVPQEFHPRTPVKLGATAGLRQLEGDASDRILQAVSDMLKNRSTLNVGADAVSVLSGNQEGAYQWVTINYLLGNLGKHYSETVAVVDLGGGSVQMAYAVSETDAAKAPRAPDGVESYITEMFLRGKKYYLYVHSYLRYGMLAARAEALKVRHSENPCILAGFDGYYVYGGVQYKAKAPPSGSSFSQCQNVVVEALHVNATCSYKDCTFGGIWNGGGGAGENNFFIASFFFEVADEAGFVDPNAPNAKVRPVDFENAAKVACNTELKDLKSIFPRVKDGDVPYICLDLVYEYTLLVDGFGIDPQQEITLVRQVEYQDSLVEAARPLGSAIEAISSLPKFEKLMYFI
Protein: Uncharacterized protein (O07719)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
Sequence:
MVLSRTSTGRVILVPTQLRFDRWFLPLAVPLGLGPKNSELWVGAGSLHVKMGWAFAADIPLTSITKAEATNARVYAAGVHFGFGRWLVNGSRKGLVALTIDPPEQAKMWKKSMTVRELWVSVTDPDALVTACTAK
Protein: Uncharacterized protein (Q388T3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGKRRVGGNSRVLRKKKVRGAKKGSCLDSVAAVIAAARGVKTVPLRIKKMTGHKRSGKRDQDVFAALRTERSKLLKRQAAERMVLKEHTRELEARRQRIRKGEDAKMERRELGKYIRQLQKEQEEKHRKELGAIEEAILLRTGKKAINKICQHEEWEDIDDDDEEGVGEHELHEMFAHLTT
Protein: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (A0A2R8Y440)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
Protein: Auxin-responsive protein SAUR72 (Protein SMALL AUXIN UP RNA 72) (Q9LTV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion. Plays a role in the regulation of cell expansion, root meristem patterning and auxin transport (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9SA49}.
Interaction partners:
- Cation/H
- Cytochrome b561 and DOMON domain-containing protein At4g12980
Sequence:
MKQLIRRLSRVADSAQYSLLRSDSQRPSRRSESFLRSSVTRRSKKQTSSVPEGHVPVYVGDEMERFVVSAELLNHPVFIGLLNRSAQEYGYEQKGVLQIPCHVLVFERIMESLRLGLPVPIDVQDLIGDGTI
Protein: Uncharacterized protein (Q586C8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- TFIIS N-terminal domain-containing protein
- Transcription initiation protein, putative
- Spt4/RpoE2 zinc finger domain-containing protein
- FACT complex subunit
- Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein
- Plastid-encoded RNA polymerase subunit alpha
- RNA polymerase-associated protein CTR9
- Cell division control protein 73 C-terminal domain-containing protein
- RNA polymerase-like protein
- DNA-directed RNA polymerase subunit beta
Sequence:
MEDINSEVGVQPTYPTREELLSKIMWVADVTDPALYLEQLHGAFEDVIFSRVQEEVEKEEDDEGLKGTRRLKTVADRMREEKRKEVLRRELMELQDDTSVDEDGSAGEHTAGDVDDDLNVDEEFLEESDFMDDREFLSWIHRNDALPREDQAEMVLKEDVPAAAGLELELHRVGLREETELETREALPERLQAIAERERRPRLQSRKISPSQSYKIRLGREAFWIICQLRGAGQPLAHNTSICALAMLPFSEVENHPVVKAVEYALKKMTQEFLEPAHLMLYHQTALQPLLCALLETSPLVEAAERSLPVASYAYSTRTGRRQRPLISDSYVGFSARGDERAIGFGDPAWDKDAQRSNGDAAAALDRMDFAQRKPCFIELGRLLLRILELDVLCHRLEWQRWQMLLKLGSSTEPDVGQEGAALRQMMFFSAIEADFWQSFVSQHVSGSNGRATRTIKSLGLESAFEQYTIAGTQYQENLRANAPIRVCPPPQSVSLLEWTSRVGASLNPPRCGETVLWLFNQAITEQFTRLPVLRTRLFNVFCAEGDLIVSYKNSKKADDVYPLASFFVEHSRHYLDLLERERQGTIDLFYVLNDELVRGVAKFGQLYDPSFNNAVGISQRDEWLTSRRDVMELVLIRLVEGLTPKVKAELSQFASRCAHTQCAERFGLLCAQGPYERTWLNIAAYDDEALVWEPEWNVVEALPRRPAGLPVTSSYGCKPPARVCAVYGGEGGLAHICFIDENGLLVGTMRWVSCALTSESGRTADLLQNIQLENQFDRCNPGVVVVGASSTASLGLMRSMQRFLRERAEANLRAHVPIVWAPVEVARLYSGTTYADSEMPDADSLSRTALALARYVQDPLGAISVLFDSRRTALRLSLGRVANITSEQEEQLYLRLCWEMSLWVTACGVWVDHCLTRSNSTALLQFISGFGPVRARKLQQLLFLRRPINKDECEKMITNAFGMHVAQNAVSSLRIGPPMDSDREVGTGEDGSLKSGRWTLLDQTLLPVAWYSTAACIACAALKRATSPHVITIRRTVAALLVADFMQRPADERRGCMDRDVRVQEITRTMRLEVRSTWSGLLGRREVEFVQDEMIASGQSFMRRPYRRISNRELMTYVTGITYCTNQDAPFLHRGVETMSLIVCEGEYIAGVVQSVRGKLAAASGVPSIRLTTSRGLNATISADDIDDETMKREFLEYEEALSALGEEGRAIGPPPNRPQWLCRGALIQGIVINCHWERCELRLRWCRPRGGEPDSRRMQKKSAARRKTRESRADVGDPAVSDGDGTDIGRHYLSYTASVRDATSCNSSLRTERLDIDARVFATKVSRHSLFRDVNSTKAVEFLQNKKIGEVLLRPASGHRNKAVAVVKIGEWSTCNWLISEDRRSNGSIYYRLSDQVEKREIEFNDVDEFLTNFIAPMVSLAQDIRAHRRFVGSTRDVLGALDAQQKSAASRTGTNGSNFIAYVFVEAEQQSRPSFYRVVTRVGTRERSFYLHISDRYIYIRVPLRTKDASAEGSRAGMVLLKCRNAEHVSQVVKELVHRC
Protein: Shikimate dehydrogenase (NADP(+)) (SDH) (EC 1.1.1.25) (Q5SJF8)
Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Function: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
Interaction partners:
Sequence:
MLRFAVLGHPVAHSLSPAMHAFALESLGLEGSYEAWDTPLEALPGRLKEVRRAFRGVNLTLPLKEAALAHLDWVSPEAQRIGAVNTVLQVEGRLFGFNTDAPGFLEALKAGGIPLKGPALVLGAGGAGRAVAFALREAGLEVWVWNRTPQRALALAEEFGLRAVPLEKAREARLLVNATRVGLEDPSASPLPAELFPEEGAAVDLVYRPLWTRFLREAKAKGLKVQTGLPMLAWQGALAFRLWTGLLPDPSGMEEAARRALGV
Protein: Apidaecin +A [Cleaved into: Apidaecin -A] (C0HKX3)
Organism: Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris)
Function: Antimicrobial peptide active against many Gram-negative enterobacterial and plant-associated bacterial species. Not active against other bacterial species like H.pylori, P.mirabilis, B.pertussis or N.gonorrhoeae.
Subcellular location: Secreted {ECO:0000269|PubMed:7929322}.
Interaction partners:
Sequence:
ANRPVYIPPPRPPHPRL
Protein: Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Neuronal tryptophan hydroxylase) (Tryptophan 5-monooxygenase 2) (Q8IWU9)
Organism: Homo sapiens (Human)
Interaction partners:
- Pterin-4-alpha-carbinolamine dehydratase
- Pterin-4-alpha-carbinolamine dehydratase 2
- Aromatic-L-amino-acid decarboxylase
- Tryptophan 5-hydroxylase 1
- Indoleamine 2,3-dioxygenase 1
- Indoleamine 2,3-dioxygenase 2
- Sepiapterin reductase
- Dihydropteridine reductase
- Tryptophan 2,3-dioxygenase
- Sodium-dependent serotonin transporter
Sequence:
MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGSSTLNKPNSGKNDDKGNKGSSKREAATESGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI
Protein: Protein OCTOPUS (Q9SS80)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potentiates primary root protophloem differentiation. Required, together with VCC, for embryo provasculature development and cotyledon vascular complexity and connectivity. Regulates roots architecture. Mediates the recruitment of ASK7/BIN2 to the plasma membrane.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22395740, ECO:0000269|PubMed:28652362}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:28652362}. Note=Polar localization at the apical side of the plasma membrane, shootward oriented, in developing root protophloem cells (PubMed:22395740, PubMed:28652362). Also found in the cytoplasm in the early, dividing. protophloem cells (PubMed:28652362). {ECO:0000269|PubMed:22395740, ECO:0000269|PubMed:28652362}.
Interaction partners:
- Serine/threonine-protein kinase BRI1-like 1
- Protein DA1-related 2
- Protein SIEVE ELEMENT OCCLUSION B
Sequence:
MNPATDPVSAAAAALAPPPQPPQPHRLSTSCNRHPEERFTGFCPSCLCERLSVLDQTNNGGSSSSSKKPPTISAAALKALFKPSGNNGVGGVNTNGNGRVKPGFFPELRRTKSFSASKNNEGFSGVFEPQRRSCDVRLRSSLWNLFSQDEQRNLPSNVTGGEIDVEPRKSSVAEPVLEVNDEGEAESDDEELEEEEEEDYVEAGDFEILNDSGELMREKSDEIVEVREEIEEAVKPTKGLSEEELKPIKDYIDLDSQTKKPSVRRSFWSAASVFSKKLQKWRQNQKMKKRRNGGDHRPGSARLPVEKPIGRQLRDTQSEIADYGYGRRSCDTDPRFSLDAGRFSLDAGRFSVDIGRISLDDPRYSFDEPRASWDGSLIGRTMFPPAARAPPPPSMLSVVEDAPPPVHRHVTRADMQFPVEEPAPPPPVVNQTNGVSDPVIIPGGSIQTRDYYTDSSSRRRKSLDRSSSSMRKTAAAVVADMDEPKLSVSSAISIDAYSGSLRDNNNYAVETADNGSFREPAMMIGDRKVNSNDNNKKSRRWGKWSILGLIYRKSVNKYEEEEEEEEDRYRRLNGGMVERSLSESWPELRNGGGGGGGPRMVRSNSNVSWRSSGGGSARKVNGLDRRNKSSRYSPKNGENGMLKFYLPHMKASRRMSGTGGAGGGGGGGWANSHGHSIARSVMRLY
Protein: AlkB homolog 3, alpha-ketoglutarate dependent dioxygenase (H0YDH4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XLTGYWNSFVKMFPGNRGLASERWHPVLRTLKNRIEENTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYPDPRGAPW