wanglab/gogpt-training-data huggingface dataset:
Protein: Intraflagellar transport protein 172 homolog (Protein wimple) (Q6VH22)
Organism: Mus musculus (Mouse)
Function: Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
Subcellular location: Cell projection, cilium {ECO:0000305}.
Interaction partners:
- Intraflagellar transport protein 88 homolog
- Intraflagellar transport protein 57 homolog
- TRAF3-interacting protein 1
- Intraflagellar transport protein 80 homolog
- Intraflagellar transport protein 52 homolog
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 20 homolog
- Intraflagellar transport protein 27 homolog
- Intraflagellar transport protein 74 homolog
Sequence:
MQLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYVIVFGLAEGKVRLANTKTNKSSTIYGTESYVVALTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRRIVAYGKEGHVLQTFDYSRDPQEREFTTAAASPGGQSVVLGSYDRLRVFNWSPRRSIWEEAKPKEIANLYTVTALAWKRDGSRLCAGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSDTLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGSNDSLGSVRTEFMNPHLISVRINERCQRGMEDNKKLAYLVDIKTIAIVDLIGGYNIGTISHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYVQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMSSIRGDVVGLERGGGKTEVMVTEGVTTVAYTLDEGLIEFGTAIDDGNYTRATAFLETLEMTPETEAMWKTLSKLALEARQLHTAERCFSALGHVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMDMYQELHRWEECIAVAEAKGHPALEKLRRDYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITTALIKGELYERAGDLFEKIRNPQRALECYCKGNAFMKAVELARLAFPVEVVRLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPRVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVEEPDLAITMFKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRSSGLWEEAYRVAKAHGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEATIDHAADNCSFEFAFELSRLAFKHKAPEIHLKYAMYLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPGQLEALQEEYEREATKKGGRGVEGLVEQARQWEQAGEYSRAVDCYLKVRDSGSSGLMEKCWMKAAELSIKFLPPQRSLEVVRVVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVVAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGGYAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNNAEAYHSWADLRDVLFNLCENLVKSSEANSAAHEEFEMMLLISHYYATRSAAQSIKQLETVAARLSVSLLRHTQLLPADKAFYEAGTAAKEVGWENMAFIFLNRFLDLTDAIEEGTLDALDHSDFQDTDIPFEVPLPAKQHVPEAQREEVRDWVLTVSMDQRLEQVLPRDERGVYEASLVAASTGVRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ
Protein: Putative transcription factor Ovo-like 1 (mOvo1) (mOvo1a) (Q9WTJ2)
Organism: Mus musculus (Mouse)
Function: Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MPRAFLVKKPCVSTCKRNWSELPDEERGEIYVPVSLGFCPPQPYREPEASVAEPPSCPLALDMSLRDSSYSVAPGPCVVAQLPSEDVSHLTDPQSRDQGFLRTKMKVTLGDSPNGDLFTCHICQKSFTHQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKERHPDSPLLRKTSKKVAVALQNTVTSLLQGSPHL
Protein: Polyamine-modulated factor 1-binding protein (F4JPL7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- SWR1-complex protein 4
- Transcription initiation factor IIF subunit alpha
- RuvB-like protein 1
- Histone acetyltransferase subunit NuA4-domain protein
- DNA-directed RNA polymerases II, IV and V subunit 11
- SWR1 complex subunit 2
- Transcription initiation factor IIF, beta subunit
- At1g75700
- DNA-directed RNA polymerase II subunit 4
- SWR1 complex subunit 6
Sequence:
MAGTSMAEPEGVKMSHDCSEEDARKELKVLLDRVKSAATSLSYLRSKARILAVPGLSLGAQQLQLKDDTTLAGTNKNKDSLVIEDGVYTLNTLQSIEMVITDALESLLRRVTAAESETCSHKEKVIICEEEITRKTVQIQNLSLRLEQTERIVMTECESLKNALTASNNVLDTLLSSSRRHFQTIEARYKLQSMLVAKSTQLEGEKAQKEVQVQKLMEENMKLTTLLDKKEAQLLALNEQCKVMALNASNI
Protein: Phenoloxidase subunit 2 (EC 1.14.18.1) (PO 2) (Tyrosinase 2) (Q27452)
Organism: Bombyx mori (Silk moth)
Function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MADVFESLELLFDRPNEPLITPKGENNSVFQLTEQFLTEDYANNGIELNNRFGDDASEKIPLKNLSKLPEFKIATQLPKDAEFSLFLPKHQEMANELLGVLMDVPENELQDLLSTCAFARVNLNPQLFNYCYSVALMHRRDTRKVRVKNFAEVFPSKFLDSQVFTQARETAAVIPPDVPRIPIIIPRDYTATDLEEEHRLAYWREDIGINLHHYHWHLVYPFTANDLSIVAKDRRGELFFYMHQQVIARFNCERLCNSLKRVKKFSNWREPIPEAYFPKLDSLTSSRGWPPRQSGMQWQDLNRAAEGLFVTIDEMERWRRNVEEAIATGTVRLPNGQTRPLDIDTLGNMLESSALSPNRELYGSIHNNGHSFTAYMHDPEHRYLEQFGVIADEATTMRDPFFYRWHAYIDDVFQKHKESAYVRPYTRSELENPGVQVRSVSVETPGGQPNTLNTFWMLSDVNLSRGLDFSDNGPVYARFTHLNYRHFSYRINVNNTGSSRRTTVRIFITPKFDERNVPWIFSDQRKMCIEMDRFVTVLNAGENNIVRQSTESSITIPFEQTFRDLSAQGNDPRRDELATFNYCGCGWPQHMLVPKGTEAGMPFQLFVMLSNYDLDRIDQDDGKQLTCVEASSFCGLKDKKYPDRRAMGFPFDRPSSSATSLQDFILPNMGLQDITIQLQNVTEPNPRNPPMSV
Protein: Zinc finger and BTB domain-containing protein 1 (Q91VL9)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional repressor (By similarity). Represses cAMP-responsive element (CRE)-mediated transcriptional activation (By similarity). In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (By similarity). Plays a key role in the transcriptional regulation of T lymphocyte development.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9Y2K1}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9Y2K1}. Note=Localized in dot-like structures in the nucleus. Colocalized with SMRT in nuclear bodies. The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies (By similarity). {ECO:0000250|UniProtKB:Q9Y2K1}.
Interaction partners:
- Transcription intermediary factor 1-beta
Sequence:
MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSRQSSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHHREPEEESLQLANFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQNTTRAYHRIVDIRDGKDSNIKAELAEKDSSKTFSAQPDKYREDANQAPDDSASTTGSRKSTVEAGIAGEEKSRATETKRIIIKMEPEDIPADDMKDFNIIKVTEKDCNESTDNDELEDEPEEPFYRYYVEEDVGIKKSGRKTLKPRMSISVDERGGLENMRPPNNTSPIQEDAENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNADEKMDMEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKGAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSGGETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT
Protein: Vacuolar amino acid transporter 6 (P40074)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in amino acid efflux from the vacuole to the cytoplasm. Capable of transporting aspartate and glutamate. Requires ATP for function.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:11274162}; Multi-pass membrane protein {ECO:0000269|PubMed:11274162}.
Interaction partners:
- Mitochondrial aspartate-glutamate transporter AGC1
- Vacuolar amino acid transporter 3
- Vacuolar amino acid transporter 4
- Vacuolar amino acid transporter 1
Sequence:
MVASIRSGVLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFIQARVAKYVPQGRASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWTRNAWLLNRNVQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISYLLPPQSHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIPLIAISLALILYIAIGCAGYLTFGDNIIGNIIMLYPQAVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFAEENVSISATSADEPTVATESSPLIRDSSLDLNEVIEEESIYQPKETPLRGKSFIVITCSILVASYLVAISVSSLARVLAIVGATGSTSISFILPGLFGYKLIGTEHKTAVPLTTKIFKYTGLLLFIWGLIIMITCLTAALKLN
Protein: Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (Prostanoid EP3 receptor) (P30557)
Organism: Mus musculus (Mouse)
Function: Receptor for prostaglandin E2 (PGE2). Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation. Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration. Not required for normal kidney function, normal urine volume and osmolality.
Subcellular location: Cell membrane {ECO:0000269|PubMed:1372606, ECO:0000269|PubMed:8223569, ECO:0000269|PubMed:8381413}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit beta-4
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Prostaglandin G/H synthase 2
- Guanine nucleotide-binding protein G
Sequence:
MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
Protein: Cst5p (A0A1D8PQE8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- G protein subunit beta
- Guanine nucleotide-binding protein subunit gamma
- mitogen-activated protein kinase kinase kinase
- Serine/threonine-protein kinase STE7 homolog
- Mitogen-activated protein kinase
- Extracellular signal-regulated kinase 1
- Cyclin-dependent protein serine/threonine kinase inhibiting protein
- Alpha-factor pheromone receptor
- Guanine nucleotide-binding protein subunit alpha
- Serine/threonine-protein kinase CST20
Sequence:
MLQSTPKSWKDFLKSPKKPTSPTTPPGSVTITPNTTPPSVPCASPRPAKIPSRDPFQTINPGLNLSFANILNKSLANHETCFICGELLSTVFASERILKLNCGDSTHSECFKAYFKEDIPHARIHGKTITFAKTCRGLNCSGTRNVVVDVNNWHLVSARKLSLIPKRPAPPHPNSVNINALKTTLQNSDIPTRSPSPDPTVSTTTEVDAYEVETVRNQLIKYLLDSCPKINLSRLVSLGNLRVADELSVCVEPSDYFQTRYVYLFENYMLIWNSVDYPVFVPMQNIQISSRGSSILQVRQKDDGLSTLIQSTSSTVVEKWVVAISDAHLQLPAPDITSTIDTSPSDSDSDIDSDEEVIQQALTKNNWADLMIEIDNALLTSDP
Protein: Pi3K21B, isoform B (Pi3K21B, isoform E) (Q7KTZ2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- phosphatidylinositol 3-kinase
- Insulin receptor substrate 1
- Insulin-like receptor
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- LD28067p)
- Serine/threonine-protein kinase mTor
- Ras-like protein 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
- Phosphatidylinositol 3-kinase catalytic subunit type 3
Sequence:
MRPQAPGSLVDPNEDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDALSMKGEYTLTLMKDGCEKLIKICHMDRKYGFIETDLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEESQPHGDLCLLSNEFIRTCQLLQNLEQNLENKRNSFNAIREELQEKKLHQSVFGNTEKIFRNQIKLNESFMKAPADAPSTEAGGAGDGANAAASAAANANARRSLQEHKQTLLNLLDALQAKGQVLNHYMENKKKEELLLERQINALKPELQILQLRKDKYIERLKGFNLKDDDLKMILQMGFDKWQQLYETVSNQPHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIRARDAGHYALSIACKNIVQHCLIYETSTGFGFAAPYNIYATLKSLVEHYANNSLEEHNDTLTTTLRWPVLYWKNNPLQVQMIQLQEEMDLEYEQAATLRPPPMMGSSAPIPTSRSREHDVVDGTGSLEAEAAPASISPSNFSTSQ
Protein: Ribonuclease VapC33 (RNase VapC33) (EC 3.1.-.-) (Toxin VapC33) (P9WF69)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB33.
Interaction partners:
- Antitoxin VapB33
- Ribonuclease VapC32
- Ribonuclease VapC4
- Ribonuclease VapC26
- Ribonuclease VapC28
- Ribonuclease VapC15
- Ribonuclease VapC11
- Ribonuclease VapC39
Sequence:
MIIPDINLLLYAVITGFPQHRRAHAWWQDTVNGHTRIGLTYPALFGFLRIATSARVLAAPLPTADAIAYVREWLSQPNVDLLTAGPRHLDIALGLLDKLGTASHLTTDVQLAAYGIEYDAEIHSSDTDFARFADLKWTDPLRE
Protein: Homeobox protein Hox-D8 (Homeobox protein Hox-4E) (Homeobox protein Hox-5.4) (P13378)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-D9
Sequence:
MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN
Protein: Uncharacterized protein (Q583X1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKKCWVFDCAAPGLYCEPRRLLKPFSTDSILDAAGRAFETVEDGLKATTWRTHHAFSARCGLTSVTRSDSTTCGKGVEESSVSRSPEDYREWHADFHLRSPSAEPHVLLSVAPHYLPSRGSGNADDGRKMEVVGSRGRWLKPWRPQTAEEQAAYDAAVLGTPLIWEEPLVLSLDCTADGVFLWSEDHGIYGEKVANRCFERHSSDAGDDSAEFKQEAFLRFRWSEQPPAQTSSVGSGRHEMKEEHVESPNVSKCGELRVFRGQRTKVEAEEPHVERISYEEADVDAGSGGFLWQSVLHRIISCGPVPKEVYFAPYVTLMESGDEVSLL
Protein: O-phosphoserine sulfhydrylase (OPS sulfhydrylase) (EC 2.5.1.113) (CysO-thiocarboxylate-dependent cysteine synthase) (Cysteine synthase B) (CSase B) (O-phosphoserine-specific cysteine synthase) ([CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase) (P9WP53)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the formation of a covalent CysO-cysteine adduct via a sulfur transfer, using the thiocarboxylated sulfur carrier protein CysO-COSH as sulfur donor and O-phospho-L-serine (OPS) as sulfur acceptor. Can also use sodium sulfide as sulfur donor in vitro, albeit with less efficiency, but not thiosulfate or thio-nitro-benzoate. O-acetylserine (OAS) is a very poor substrate in comparison with OPS. May be of particular importance for cysteine biosynthesis in the persistent phase of M.tuberculosis.
Interaction partners:
- Sulfur carrier protein CysO
- CysO-cysteine peptidase
- Glutamate racemase
- Uncharacterized protein Rv1337
- Serine acetyltransferase
- Probable adenylyltransferase/sulfurtransferase MoeZ
- Bifunctional enzyme CysN/CysC
- Oxidative stress regulator AosR
- Uncharacterized aminopeptidase Rv1333
- Uncharacterized protein Rv1339
Sequence:
MTRYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYLSTGAYAGSLDDAETALEGQLWA
Protein: Large ribosomal subunit protein eL18 (60S ribosomal protein L18) (P50885)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- 60S ribosomal subunit protein L31, putative
- 40S ribosomal protein S5, putative
- Ribosomal protein L37
- 40S ribosomal protein S4
- 60S ribosomal protein L35A, putative
- 40S ribosomal protein S27, putative
- 40S ribosomal protein S15, putative
- Small ribosomal subunit protein uS4
- 60S acidic ribosomal protein P0
- 60S ribosomal protein L6, putative
Sequence:
MGVDLTGVQKKKRVVRHHTYSTNPYIKLLIKLYKFLGKRTNSPFNKLIHKRLLKSRNNRAPISLSRIAVCMRRRTVWLKKGKKSPIAVIVGDVLDDVRMTRIPALRICALRFSKSARERITGAGGECLTFDQLAMMAPTGKNTMLLRGRKSGRESVKHFGAAGVPGSHAKPHVSSRGKERQRSSKRRHAFRHK
Protein: Uncharacterized leucine-rich repeat-containing protein C926.06c (Q9UUG2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}. Vacuole membrane {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Protein mms22
- Uncharacterized protein C3H8.05c
Sequence:
MGSTVDGEKYIRNLASYIRSHEKRFARAPYRAPNHSIFSDRPVQLQLTVHHLYYLLTKFEELGVNTGPLNIRIENLHSETFPSDYTSFLNQSPKKNDFDDNMSLNSIVTMGSILSNVSSVWSIFSTAPSEASETRNKQRILAILRYIYSCFTKLPAISLVYNPKTPLISQYEEFPLDTAVPITVFKNLSSLEIRGYDIRSIFGWDFLSTTLKSLILHHCDLADLSEVLIKLVLDDAELYRFRSSRQTYPQQPNSQPCEQHPAHANLRRSVSLGSKDYLKSSHPPVHKTLSQSVLVLSKDGNASSSGGTENQSANSSSSLMEKDAILSSSSWSQLLYLRCSSCKLKSIPKNVFLSLQSLVSLDLSGNELTEIPYALGELPQLCSLNLASNKITGCRTFYHISLSHLQILVLSRNHLTSLSGLENVPSLEKLDIRDNSITDVVEFRRLVGNTNFEEAYLSLNPFTKTYSSYRITIFNYFREYPGSKDIMLDGRGPGMLEKMYLSEKASAPERVISLNPVNQKSHSPAIKSSSTLRKASKTRIVDLSAPNSAVFSKNASGGDTSSNVSLLNGSASEEIPQNTESGQVFRKKIEMLRQEAGPEWVDALMKESVVKHKFRNKDESV
Protein: IQCJ-SCHIP1 readthrough transcript protein (A0A088MLT8)
Organism: Mus musculus (Mouse)
Function: May play a role in action potential conduction in myelinated cells through the organization of molecular complexes at nodes of Ranvier and axon initial segments. May also play a role in axon outgrowth and guidance.
Subcellular location: Cell projection, axon {ECO:0000269|PubMed:18550753}. Cytoplasm {ECO:0000250|UniProtKB:B3KU38}. Note=Localizes to the axon initial segments (AIS) and nodes of Ranvier of neurons and is absent from dendrites. {ECO:0000269|PubMed:18550753}.
Interaction partners:
- Serine/threonine-protein kinase TAO2
Sequence:
MRLEELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLSSSVSMNTFSDSSTPDYREDGMDLGSDAGSSSSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGEEEEEEDDRGYRDDGCPAREPGDVSARIGSSGSGSRSAATTMPSPMPNGNLHPHDPQDLRHNGNVVVAGRPNASRVPRRPIQKTQPPGSRRGGRNRASGGLCLQPPDGGTRVPEEPPAPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSARLQSGMNLQICFVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLMKRSLKPTDLRDMTIGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHMAEKMPAK
Protein: AN1-type zinc finger protein 2A (Arsenite-inducible RNA-associated protein) (Q9JII7)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11525245}. Nucleus {ECO:0000269|PubMed:11525245}.
Interaction partners:
Sequence:
MEFPDLGKHCSEPTCKQLDFLPITCDACKQDFCKDHFSYVGHKCPFAFKKDVQVPVCPLCNAPIPVKRGEIPDVVVGEHMDRDCTFHPGRNRNKVFTHRCSKEGCRKKEMLQLACAQCHGNFCIQHRHPLDHNCQAGSSSASRGRTSTSRAAEQKPSGVSWLAQRLRRTVK
Protein: Solute carrier family 25 member 48 (Q8BW66)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MGSFQLEDFVAGWIGGVASVIVGYPLDTVKTRLQAGVGYANTFNCIRMVYKRERVFGFFKGMSFPLASIAIYNSVVFGVFSNTQRFLSKYRCGELEAGPGRSLSDLLLASMLTGVVSVGLGGPVELIKIRLQMQTQPFREASHGLKSRAVAAYQGPVHCIATIVQMEGLTGLYRGASAMLLRDIPGYCFYFIPYVFLSEWITPEACTGPSPYAAWLAGGIAGAISWGTATPMDVVKSRIQADGVYLNKYRGVVDCISQSYQQEGFKVFFRGITVNAVRGFPMSAAMFLGYELSLKALRGEHTVRSE
Protein: Outer membrane protein X (P0A917)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell outer membrane; Multi-pass membrane protein.
Interaction partners:
- Outer membrane porin C
- Outer membrane protein A
- Outer membrane protein W
- Outer membrane porin F
- Chaperone protein Skp
- Periplasmic serine endoprotease DegP
- Long-chain fatty acid transport protein
- Maltoporin
- Lipid A palmitoyltransferase PagP
- Protease 7
Sequence:
MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF
Protein: COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (JAB1-containing signalosome subunit 8) (Q8VBV7)
Organism: Mus musculus (Mouse)
Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 2
- COP9 signalosome complex subunit 7a
- COP9 signalosome complex subunit 7b
- Ubiquitin-like protein NEDD8
- Cullin-4A
Sequence:
MPVAVMADNAFSFRKLLDQCENQELEAPGGIATPPVYGQLLALYLLQNDMNNARYLWKRIPPAIKSANSELGGIWSVGQRIWQRDFPGIYTTINAHQWSETVQPIMEALRDATRRRAFALVSQAYTSIIADDFAAFVGLPVEEAVKGVLEQGWQADSTTRMVLPRKPASGTLDVSLNRFIPLSEPAPVPPIPNEQQLARLTDYVAFLEN
Protein: T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (M0R576)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MKWTASVLACILQVQFPGAEAQSFGLLDPKLCYMLDGILFIYGVIVTALYLRAKFSRSADAAAYLQDPNQLYNELNLGRREEYDVLDKKRPRDPEMGGKQQRRRNPQEGVYNALQKDKMAEAYSEIGMKGERRRGKGHDGLYQDSHFQASGNRKEKEGSEALGLRPRPKGESTQQSSQSCASIFSFPTLWSPWPHRSSAQL
Protein: Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase (PhPPA-AT) (EC 2.6.1.1) (EC 2.6.1.78) (EC 2.6.1.79) (E9L7A5)
Organism: Petunia hybrida (Petunia)
Function: Prokaryotic-type aspartate aminotransferase. Has also a prenate transaminase activity. Involved in the aromatic amino acids biosynthesis pathway via the arogenate route. Required for the transamination of prephenate into arogenate. Can use 2-oxoglutarate, oxaloacetate and prephenate as substrates, but not phenylpyruvate or 4-hydroxyphenylpyruvate.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
Sequence:
MAATTTTSSSSRIAYSRHNIPGLHSDSLNPKSISFSSNLHTFSLKSSGSRRQLYSRRTGAVVIMQSMDKVEVDISLSPRVNSVKPSKTVAITDQATALVQAGVPVIRLAAGEPDFDTPAPIVEAGINAIREGHTRYTPNAGTMELRSAISHKLKEENGLSYTPDQILVSNGAKQSIIQAVLAVCSPGDEVLIPAPYWVSYPEMARLADATPVILPTSISEDFLLDPKLLESKLTEKSRLLILCSPSNPTGSVYPRKLLEQIAEIVARHPRLLVISDEIYEHIIYAPATHTSFASLPGMWDRTLTVNGFSKAFAMTGWRLGYIAGPKHFIAACNKIQSQFTSGASSISQKAAVAALGLGYAGGELVATMVKSFRERRDYLVKSFGEIEGVKISEPRGAFYLFIDLSSYYGVEVDGFGSINNSESLCRYLLDKAQVALVPGDAFGDDTCIRISYAASLSTLQAAVERIKKALVTIKPPVPV
Protein: Keratin-associated protein 12-4 (High sulfur keratin-associated protein 12.4) (Keratin-associated protein 12.4) (P60329)
Organism: Homo sapiens (Human)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Interaction partners:
Sequence:
MCHTSHSSGCPMACPGSPCCVPSTCYPPEGYGTSCCCSAPCVALLCRPLCGVSTCCQPACCVPSPCQVACCVPVSCKPVLCVASFCPTSGCCQPFCPTLVYRPVTWSTPTGC