wanglab/gogpt-training-data huggingface dataset:
Protein: Nrf2b (Nuclear factor erythroid 2-related factor 2b) (G8DKA8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDDLSAQFQHESAVIDILWRQDVDLGVEREIFDGCLRQREEETMRERTRERDLKRERELERIMQRLQKLDEETGECLPSPSSVNSQAVPFSEMLPSTMSIQSSPVTQNPLLSALLFSQKPQKLPSQKQGFGELASLPDLQYYLDVLESESSSLPLEDIAEICQPNLPDPHPENSTDAFCCVSELTQAISDSLPCLPSDPVEVLETCIQTLSDSSNSMYSPSNAVYSPESELILPKTQINDSVLSEFCSELNTYTINADQLNMAPAQQTLSQFEERHVMLGFDDSASVGSVDLETSLYESLSNEQSDKDELESIQSDYTDLLSLSADAMMYETVTNAQEQTQKTRVRRGCRDEQRAQALSLPLSVHDIIHLPVEAFNEAISTCKLNHAQHTLIRDIRRRGKNKMAAQSCRKRKMDSLFGLEDEIEDLKRKKDQCMEEKERNARELCETKEKVRKLYNEVFRLLKDEHGNSYNPREYKLQLSTDGTVYLLPRNTALKNKMSSGDLNVAV
Protein: Co-chaperonin GroES (10 kDa chaperonin) (Chaperonin-10) (Cpn10) (O51683)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00580}.
Interaction partners:
- Chaperonin GroEL
- Protein GrpE
- Chaperone protein DnaK
- ATP-dependent protease ATPase subunit HslU
- ATP-dependent protease subunit HslV
- Chaperone protein HtpG
- Heat shock protein 70
- ATP-dependent Clp protease proteolytic subunit 1
- Thioredoxin
- ATP-dependent Clp protease proteolytic subunit 2
Sequence:
MKNIKPLADRVLIKIKEAESKTISGLYIPENAKEKTNIGTVIAVGSNKEEITVKVGDTVLYEKYAGAAVKIENKEHLILKAKEIVAIIEE
Protein: Protein ABERRANT PANICLE ORGANIZATION 1 (F-box protein 0393) (Os_F0393) (F-box protein 321) (OsFbox321) (Protein PRIMARY BRANCH NUMBER ON CHROMOSOME 6) (Protein STRONG CULM 2) (Q655Y0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Together with FL/APO2, involved in the temporal regulation of meristem identity during both vegetative and reproductive developments in an APO2-dependent manner. Promotes spikelet formation by suppressing the precocious conversion of inflorescence meristems to spikelet meristems, probably via a positive regulation of class-C floral homeotic genes, but not of class-B genes, and through the control of cell proliferation in meristems. Mediates culm development and strength/diameter enhancement at internodes. Required for the regulation of the plastochron, floral organ identity, and floral determinacy. Controls the number of primary rachis branches (PRBs). May trigger the formation of vascular bundle systems which, consequently, promote carbohydrate translocation to panicles. Involved in ozone-induced grain yield regulation.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Probable transcription factor FL
Sequence:
MMNPRRLPPLPSSTSSASAADDMDPRVWRRLPQPLVDRILACLPTPSFLRLRAACRRFYHLLFSSPFLHSHLLLSPHLPFFAFVVPAAGHLLLLDPTATASWSRLPLPLPPVAGGPAAFSPAAASAGLLAFLSDASGHKTLLLANPITRLLAALPISPTPRLSPTVGLAAGPTSIIAVVAGDDLVSPFAVKNISADTFVADAASVPPSGFWAPSSLLPRLSSLDPRAGMAFASGRFYCMSSSPFAVLVFDVAENVWSKVQPPMRRFLRSPALVELGGGREGAARVALVSAVEKSRLSVPRSVRLWTLRGGGGGGGGGAWTEVARMPPEVHAQFAAAEGGRGFECAAHGDYVVLAPRGPVAQAPTSALVFDSRRDEWRWAPPCPYVVVAHHGGAGAAGFRVFAYEPRLATPAIGLLDATAPVALHGMHDG
Protein: Phosphate acetyltransferase (EC 2.3.1.8) (Phosphotransacetylase) (P0A9M8)
Organism: Escherichia coli (strain K12)
Function: Involved in acetate metabolism. Catalyzes the reversible interconversion of acetyl-CoA and acetyl phosphate. The direction of the overall reaction changes depending on growth conditions. On minimal medium acetyl-CoA is generated. In rich medium acetyl-CoA is converted to acetate and allowing the cell to dump the excess of acetylation potential in exchange for energy in the form of ATP. The main pathway for acetate production during exponential phase.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Acetate kinase
- Propionate kinase
- Formate acetyltransferase 1
- Bifunctional aldehyde-alcohol dehydrogenase AdhE
- Acetyl-coenzyme A synthetase
- PFL-like enzyme TdcE
- Malate synthase A
- Acetaldehyde dehydrogenase
- 2-methylcitrate synthase
- Malate synthase G
Sequence:
MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRTGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFGGAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ
Protein: Ras-related protein Rab-6B (EC 3.6.5.2) (Q9NRW1)
Organism: Homo sapiens (Human)
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology (Probable). Recruits VPS13B to the Golgi membrane. Regulates the compacted morphology of the Golgi. Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Plays a role in neuron projection development.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:17707369, ECO:0000269|PubMed:18044744, ECO:0000269|PubMed:25492866}; Lipid-anchor {ECO:0000305}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:17707369}. Cytoplasmic vesicle {ECO:0000269|PubMed:17707369}. Note=Colocalizes with BICD1 at vesicular structures that align along microtubules. {ECO:0000269|PubMed:17707369}.
Interaction partners:
- GRIP and coiled-coil domain-containing protein 2
- Rab GDP dissociation inhibitor beta
- Ras-related protein Rab-6A
- Guanine nucleotide exchange factor subunit RIC1
- Rab GDP dissociation inhibitor alpha
- TATA element modulatory factor
- Ganglioside-induced differentiation-associated protein 1
- ADP-ribosylation factor-like protein 1
- Vam6/Vps39-like protein
- Vacuolar protein sorting-associated protein 52 homolog
Sequence:
MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (F5H5B4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTDGANTMIEHDDTLPSQLGTMVINAEDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSDWKIPQDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF
Protein: 5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2) (Q63147)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. Contributes significantly to heme formation during erythropoiesis (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:2369125}; Peripheral membrane protein {ECO:0000305}. Note=Localizes to the matrix side of the mitochondrion inner membrane. {ECO:0000269|PubMed:2369125}.
Interaction partners:
- Delta-aminolevulinic acid dehydratase
- Ferrochelatase
- Alpha-hemoglobin-stabilizing protein
- Iron-sulfur clusters transporter ABCB7, mitochondrial
- Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
- Uroporphyrinogen decarboxylase
- Band 3 anion transport protein
- Erythroid transcription factor
- Porphobilinogen deaminase
- Amine oxidase
Sequence:
MVAAAMLLRSCPVLSKGPTGLLGKVAKTYQFLFGIGRCPILATQGPTCSQIHLKATKAGADSPSWTKSHCPFMLSELQDRKSKIVQRAAPEVQEDVKTFKTDLLSFMESTTRSQSVPRFQDPEQTGGAPPLLIQNNMTGSQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQHFSEASMDSKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHHKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAVKFVFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGTRGAGIGERDGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLAKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
Protein: Transporter (R4N225)
Organism: Dicentrarchus labrax (European seabass) (Morone labrax)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MKLKLPNPGLDDRIPSHGDLERMEKEEAGDRPKWDNKAQYLLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWRSISPYLTGVGIASMLVSFLVGMYYNTIMAWIMWYLFNSFQDPLPWSQCPLNANRTGLVEECARSSTVDYFWYRETLNTSTAIDEAGGLQWWMVLSLVAAWTLLYVCSIRGIETTGKAVYITSTLPYLVLTIFLVRGLTLKGSIDGIKFLFTPDVNELMNPSTWLDAGAQVFYSFSLAFGGLISFSSYNSIHNNCEQDAVLISIINGCTSVYSATVIYSIIGFRATQKFDDCMGNNIWKLMNAFDYPENNITDSNYNEVLAHLNQTNPEIIQGLELQTCDLQSFLSQGVEGTGLAFIVFTEAIIKMPVSPLWAVLFFVMLFCLGLSTMFGNIEGVVVPLQDLRLLPRTWPKEVFCGLTCLISLALGLIFTLRSGNYWLALFDNFAGSIPLLVIGFCEMFAVIYIYGIDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMIFILIFYFVTQISKSLTYLVWDQESENFPTLEARPHPSWINVMIFILAGVPSLAIPVFALFKFIQNKCCKKDHNDFTVDTISAKIQMSDKMKL
Protein: Neurotrypsin (EC 3.4.21.-) (Brain-specific serine protease 3) (BSSP-3) (Motopsin) (Serine protease 12) (O08762)
Organism: Mus musculus (Mouse)
Function: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
Subcellular location: Secreted.
Interaction partners:
- Agrin
Sequence:
MALARCVLAVILGALSVVARADPVSRSPLHRPHPSPPRSQHAHYLPSSRRPPRTPRFPLPLRIPAAQRPQVLSTGHTPPTIPRRCGAGESWGNATNLGVPCLHWDEVPPFLERSPPASWAELRGQPHNFCRSPDGSGRPWCFYRNAQGKVDWGYCDCGQGPALPVIRLVGGNSGHEGRVELYHAGQWGTICDDQWDNADADVICRQLGLSGIAKAWHQAHFGEGSGPILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCVPLTDGVIRLAGGKSTHEGRLEVYYKGQWGTVCDDGWTEMNTYVACRLLGFKYGKQSSVNHFDGSNRPIWLDDVSCSGKEVSFIQCSRRQWGRHDCSHREDVGLTCYPDSDGHRLSPGFPIRLVDGENKKEGRVEVFVNGQWGTICDDGWTDKHAAVICRQLGYKGPARARTMAYFGEGKGPIHMDNVKCTGNEKALADCVKQDIGRHNCRHSEDAGVICDYLEKKASSSGNKEMLSSGCGLRLLHRRQKRIIGGNNSLRGAWPWQASLRLRSAHGDGRLLCGATLLSSCWVLTAAHCFKRYGNNSRSYAVRVGDYHTLVPEEFEQEIGVQQIVIHRNYRPDRSDYDIALVRLQGPGEQCARLSTHVLPACLPLWRERPQKTASNCHITGWGDTGRAYSRTLQQAAVPLLPKRFCKERYKGLFTGRMLCAGNLQEDNRVDSCQGDSGGPLMCEKPDESWVVYGVTSWGYGCGVKDTPGVYTRVPAFVPWIKSVTSL
Protein: ER membrane protein complex subunit 10 (Q8IPT0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
Interaction partners:
- ER membrane protein complex subunit 7
- ER membrane protein complex subunit 4
- ER membrane protein complex subunit 3
- ER membrane protein complex subunit 1
- Membrane magnesium transporter
- ER membrane protein complex subunit 2
- ER membrane protein complex subunit 2
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 8/9 homolog
Sequence:
MYSKAGFVLIFVLGLVSSSWGFLEHDSWITVELQHSLAANSESFSFRGNVTIPSLNSGLANVEQPDLSTADLDLLKKLALGNEFYRLKATVVYSNGAKAQFITSNKACRLLQAQLNDVLWVSLEPSGYVTGITVSQDTAPATIECTQEDVNKLLETQFSTDVLIRHAELAPVPDTAGFIQKVEREREARERGEVRDNRGFFAKYWMYIVPVVLLVFISGATNQDGAK
Protein: Magnesium-activated aldehyde dehydrogenase, cytosolic (EC 1.2.1.-) (EC 1.2.1.4) (Mg(2+)-activated acetaldehyde dehydrogenase) (Mg(2+)-ACDH) (P54115)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Cytosolic aldehyde dehydrogenase which utilizes NADP(+) as the preferred coenzyme. Performs the conversion of acetaldehyde to acetate.
Subcellular location: Cytoplasm.
Interaction partners:
- Acetyl-coenzyme A synthetase 2
- Acetyl-coenzyme A synthetase 1
- NADP-dependent alcohol dehydrogenase 6
- Alcohol dehydrogenase 4
- Acyl-coenzyme A oxidase
- NADP-dependent alcohol dehydrogenase 7
- NADP-specific glutamate dehydrogenase 1
- Acetyl-CoA hydrolase
- Isocitrate dehydrogenase cytoplasmic
- 4-aminobutyrate aminotransferase
Sequence:
MTKLHFDTAEPVKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL
Protein: Dehydration-responsive element-binding protein 2C (Protein DREB2C) (Q8LFR2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- ABSCISIC ACID-INSENSITIVE 5-like protein 5
- ABSCISIC ACID-INSENSITIVE 5-like protein 7
- Heat stress transcription factor A-3
- ABSCISIC ACID-INSENSITIVE 5-like protein 6
- Histone H4
- FACT complex subunit SSRP1
- Probable protein phosphatase 2C 33
- Heat stress transcription factor A-2
- Heat stress transcription factor A-1a
- Heat stress transcription factor A-1b
Sequence:
MPSEIVDRKRKSRGTRDVAEILRQWREYNEQIEAESCIDGGGPKSIRKPPPKGSRKGCMKGKGGPENGICDYRGVRQRRWGKWVAEIREPDGGARLWLGTFSSSYEAALAYDEAAKAIYGQSARLNLPEITNRSSSTAATATVSGSVTAFSDESEVCAREDTNASSGFGQVKLEDCSDEYVLLDSSQCIKEELKGKEEVREEHNLAVGFGIGQDSKRETLDAWLMGNGNEQEPLEFGVDETFDINELLGILNDNNVSGQETMQYQVDRHPNFSYQTQFPNSNLLGSLNPMEIAQPGVDYGCPYVQPSDMENYGIDLDHRRFNDLDIQDLDFGGDKDVHGST
Protein: Growth hormone (Q0QBG3)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MMAAGPRTSLLLAFTLLCLLWTQVVGAFPAMSLSRLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
Protein: Centlein (Centrosomal protein) (Q9NXG0)
Organism: Homo sapiens (Human)
Function: Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:24554434}. Note=Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434). {ECO:0000250|UniProtKB:A9ZSY0, ECO:0000269|PubMed:24554434}.
Interaction partners:
- Pericentrin
- Leucine-rich repeat-containing protein 45
- Rootletin
- Ninein
- Centrosomal protein of 135 kDa
- Centrosome-associated protein CEP250
- Centrosomal protein of 170 kDa
- Centriolar coiled-coil protein of 110 kDa
- Centrosomal P4.1-associated protein
- Serine/threonine-protein kinase PLK4
Sequence:
MAARSPPSPHPSPPARQLGPRSPRVGRGAEVHAMRSEASGFAGAAREVVADESDKIWVGEEGSGGRRGPGGAAPAHAPLLSAPMGSRRLEGISVEEAMVTRTQLLEEELSSLKEELALCQADKEFVWSLWKRLQVTNPDLTQVVSLVVEREKQKSEAKDRKVLEILQVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPQESDPDYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKVKFKAAKKNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDGKDQKESDPTEDSQTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQKKNCKMQKSSHTAVPTRVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAENDKEWMLYIQKLLEGQSLTLSPRLKCNGAIVAHQNLRLPDSSSSASAS
Protein: Hydroxycarboxylic acid receptor 1 (G-protein coupled receptor 104) (G-protein coupled receptor 81) (Q9BXC0)
Organism: Homo sapiens (Human)
Function: Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Density-regulated protein
Sequence:
MYNGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPKQPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDPHIVEWH
Protein: Laccase-2 isoform B (Q58IU2)
Organism: Anopheles gambiae (African malaria mosquito)
Interaction partners:
Sequence:
MAIDWRNRVLSLGILLALAVAADGVRVQQHTSRRFKDESFGHDQTPAGSWWSSHLTEPPSNFYQATHGLLQTHPSVPSLKPVAGAPAAPGPSALPLSSRKSPTVSSAAALNSGFPSIANPNPRSPFRHLDFSTSATAELRRNPSLSAPDECARACREGEPPRICYYHFTVEYYTVLGAACQVCTPNATNTVWSHCQCVLADGVERGILTVNRMIPGPSIQVCENDRVVIDVENHMEGMELTIHWHGIWQRGTQYYDGVPFVTQCPIQQGNTFRYQWTGNAGTHFWHAHTGLQKLDGLYGSIVVRQPPSRDPNSHLYDFDLTTHIMLVSDWLHEDAAERYPGRLAVNTGQDPESLLINGKGQFRDPNTGFMTNTPLEIFTITPGRRYRFRMINAFASVCPAQVTIEGHALTVIATDGEPVHPVQVNTIISFSGERYDFVITADQPVGAYWIQLRGLGECGIKRAQQLAILRYARGPYQPASPPPTYDVGLPQGVVMNPLDAVCNVPRPDAVCVSNLRNAKKADKAVLSERPDVKIFLPFRFYFYRVEELFTPNTYNKFLVAPGGDHLISLIDEISYVSPPSPMLSQINDIPPEQFCNGDNRPPDCGPNCMCTHKVDIPLNAIVEVVLVDEVQQENLSHPFHLHGHAFHVIGMGRSPDSTVKKINLRHTLDLDRRGLLNRQFNLPPLKDTIAVPNNGYVVLRFRADNPGYWLFHCHFQFHIVIGMNLVVHIGTHADLPPVPPNFPRCGNHIPPIKYN
Protein: Uncharacterized protein (Q57XG0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- fumarate reductase
Sequence:
MLMFHLNANRHLLQPPTKNRRGEVVSQTQRNRVCPAAIRAYRFLSDDISSQLNICCAVLQVPFSGIPGAPPSTVVTKESVHPSSMLVVWNDTTAAEIAMSLLREVRGDVDSAFAAAESATKAEGADEVVGAANPEDNLGASRDDSATAVYVIKLSVGAVSADGNATLSPIASVELRQVIRGEPLVFPSRRAGMPAVDVPISTLPYRLGDPIFFTCKRLR
Protein: Ribosomal RNA small subunit methyltransferase G (EC 2.1.1.-) (16S rRNA 7-methylguanosine methyltransferase) (16S rRNA m7G methyltransferase) (Glucose-inhibited division protein B) (P9WGW9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00074}.
Interaction partners:
- Probable chromosome-partitioning protein ParB
- Probable chromosome partitioning protein ParA
- Small ribosomal subunit protein uS12
- DNA-directed RNA polymerase subunit beta
- Conserved protein similar to jag protein
- DNA gyrase subunit A
- 16S/23S rRNA
- Probable arabinosyltransferase B
- DNA gyrase subunit B
- Nicotinamidase/pyrazinamidase
Sequence:
MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLAIARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRMLAIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA
Protein: Serine/threonine-protein kinase (EC 2.7.11.13) (A0A0B4KHC3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|PIRNR:PIRNR000552}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Uncharacterized protein, isoform A
Sequence:
MEGPEVTFLFQFGSVRDAVCVPANSLTLKTLKDLACDFINTKIPDSGLTYLSERILLFVHDYSTPNVLHIINSAAEVVDETLVEIVLTASPILYPTSEMPTLKPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNCNRSNDATSRRSFTLQAPRSPSGSSQQSLVSTEDSTGRNDSSSSLNIPGRHQRTHSSGSRNGLMVLRIPHTFMVHTYGIPTVCQLCKKLLKGLFKQGLQCRDCQYNTHKKCMDKVPHDCTGEAQLSQLQIQAGAKERDNFFREEFDDSDGDDGSEYGKYKSAMSSGVNLVAGRPREAPKALTNAHNSPPELVNGGLVDDSSVSGGETSKSSSDGQSEQSQSSTSSSPSANIPLMRIVQSVKHTKKRGGQALKEGWLVHYTSLDKAVKRYYWRLDSKTITLFVSEQGSKYHKELPLAELLSIESHLGDPRPECNYCFELRLPNLSYFVGQDPQVGAKEEQAVRLPPPDSGIGSDIAKSWETSIRQAFMHVTNTQCCESEEQVQDMGQLYQIFPDEVLGSGQFGVVYGGVHKKTQREVAIKVIDKLRFPTKQEAQLKNEVAILQNISHCGVVNLERMFETPERIFVVMEKLKGDMLEMILSHARGRLSERVTKFLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEEEDINDQIQNAAFMYPPNPWKEISSNAIDLINNLLQVKQRKRYTVDKSLLHYWLQDKQTYRDLRNLEAQVGAGRYLTHEADDLRWDCAGDMXPGCEPEAILESTTELISCSANTTTESYRRSPADCAGCHRLSDCGNSPKSEAMSDRALKWMRFHLCRHIK
Protein: Protein FAM110C (Q1W6H9)
Organism: Homo sapiens (Human)
Function: May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17499476, ECO:0000269|PubMed:19698782}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17499476, ECO:0000269|PubMed:19698782}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:17499476, ECO:0000269|PubMed:19698782}. Nucleus {ECO:0000269|PubMed:17499476, ECO:0000269|PubMed:19698782}. Note=Colocalizes with microtubules during interphase (PubMed:17499476). Detected at the mitotic spindle poles (PubMed:17499476). Colocalizes with AKT1 at the cell cortex (PubMed:19698782). {ECO:0000269|PubMed:17499476, ECO:0000269|PubMed:19698782}.
Interaction partners:
- Centrosome and spindle pole-associated protein 1
Sequence:
MRALAALSAPPNERLLPRDPAATRDPDAARPARRSAVERLAADRAKYVRGRPGTGRGVASEGSGPGAIKCPGNDPGPPARAPAPVARRAIARKPLRPDSLIIYRQKCEFVRGSGADGPRASLVKKLFQGPGKDKAPVPRTGDEGKAGNPETVPTTPGPAADPAIPETPAPAARSAAPSSVPAAPPGPEPRVVRRRGLQRSQSDLSSRYSAALAESDTFFQYCGLDPEVVEALGRENFTAGSDCVTLKVRSVSVATSGSGFSRHSGGDDEGLQEEELIEQVPSTTSVIERNARIIKWLYTCKKAKETPSQEQSRTRGSKPSR