wanglab/gogpt-training-data huggingface dataset:
Protein: UDP-glycosyltransferase 76E1 (SlUGT76E1) (EC 2.4.1.263) (K4D3V7)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Glucosyltransferase acting on abscisic acid (ABA) but not on auxin (IAA).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:28482127}. Nucleus {ECO:0000269|PubMed:28482127}.
Interaction partners:
Sequence:
MKIERKQSVVLVPHPYQGHLTPMLQLGSILHSQGFSVIVAHTQYNTPNYSNHPQFVFHSMDDGLQGIDMSFPSLENIYDMNENCKAPLRNYLVSMMEEEGDQLACIVYDNVMFFVDDVATQLKLPSIVLRTFSAAYLHSMITILQQPEIYLPFEDSQLLDPLPELHPLRFKDVPFPIINNTVPEPILDFCRAMSDIGSSVATIWNTMQDLESSMLLRLQEHYKVPFFPIGPVHKMASLVSSTSILEEDNSCIEWLDRQAPNSVLYVSLGSLVRIDHKELIETAWGLANSDQPFLWVIRPGSVSGFQCAEALPDGFEKMVGERGRIVKWAPQKQVLAHPAVAGFFTHCGWNSTLESICEEVPMVCRPFLADQLVNARYLSQIYKVGFELEVIERTVIEKTIRKLMLSEEGKDVKKRVADMKQKIVAGMQIDCTSHKNLNDLVDFISALPSRLAPPTPVFGAIMSSNHIASKCIIES
Protein: Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (CD antigen CD71) (Q99376)
Organism: Rattus norvegicus (Rat)
Function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (By similarity). Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway (By similarity). When dietary levels of stearate (C18:0) are low, promotes activation of the JNK pathway, resulting in HUWE1-mediated ubiquitination and subsequent degradation of the mitofusin MFN2 and inhibition of mitochondrial fusion (By similarity). When dietary levels of stearate (C18:0) are high, TFRC stearoylation inhibits activation of the JNK pathway and thus degradation of the mitofusin MFN2 (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P02786}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P02786}. Melanosome {ECO:0000250|UniProtKB:P02786}.
Interaction partners:
- Hereditary hemochromatosis protein homolog
- Serotransferrin
- Hemojuvelin
- Ferritin heavy chain
- Beta-2-microglobulin
- Ferroportin
- Natural resistance-associated macrophage protein 2
- T-cell surface glycoprotein CD4
- Lactotransferrin
- Heat shock cognate 71 kDa protein
Sequence:
MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENADSNMKASVRKPKRFNGRLCFATIAVVIFFLIGFMIGYLGYCKRVEQKEECVRLAEAEEADKSENDETEYVPKSSRLFWADLKTLLSEKLNSIEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQVKNSVSQNLVTINSGSNIDPVEAPEGYVAFSKAGEVTGKLVHANFGTKKDFEELNYSVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRNTFPVVEADLQFFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAAEKLFKNMEGNCPPSWNIDSSCKLELSQNQNVKLTVNNVLKETRILNIFGVIKGYEEPDRYIVVGAQRDAWGPGVAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDYGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPIDGKYLYRDSNWISKIEELSLDNAAFPFLAYSGIPAVSFCFCEDEDYPYLGTKLDTYEILIQKVPQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQFKADIKDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLRLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF
Protein: Proto-oncogene vav (P15498)
Organism: Homo sapiens (Human)
Function: Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Interaction partners:
- Cell division control protein 42 homolog
- Lymphocyte cytosolic protein 2
- Tyrosine-protein kinase ZAP-70
- Growth factor receptor-bound protein 2
- B-cell linker protein
- Tyrosine-protein kinase SYK
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Tyrosine-protein kinase ITK/TSK
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- B-lymphocyte antigen CD19
Sequence:
MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDLMRSEPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC
Protein: Pumilio domain-containing protein 6 (O01322)
Organism: Caenorhabditis elegans
Function: RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-5 and puf-7 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.
Interaction partners:
- Nanos-type domain-containing protein
- PIP-1
- Pumilio domain-containing protein 12
- RNA-binding protein pos-1
- Zinc finger protein mex-5
- Inactive protein-tyrosine phosphatase egg-4
- Exonuclease domain-containing protein
- CCCH-type zinc finger protein oma-1
Sequence:
MTPNRRSTDSYNMLGASFDFDPDFSLLSNKTHKNKNPKPPVKLLPYRHGSNTTSSDLDNYIFNSGSGSSDDETPPPAAPIFISLEEVLLNGLLIDFAIDPSGVKFLEANYPLDSEDQIRKAVFEKLTESTTLFVGLCHSRNGNFIVQKLVELATPAEQRELLRQMIDGGLLVMCKDKFACRVVQLALQKFDHSNVFQLIQELSTFDLAAMCTDQISIHVIQRVVKQLPVDMWTFFVHFLSSGDSLMAVCQDKYGCRLVQQVIDRLAENPKLPCFKFRIQLLHSLMTCIVRNCYRLSSNEFANYVIQYVIKSSGIMEMYRDTIIDKCLLRNLLSMSQDKYASHVIEGAFLFAPPALLHEMMEEIFSGYVKDVELNRDALDILLFHQYGNYVVQQMISICTAALIGKEERQLPPAILLLYSGWYEKMKQRVLQHASRLERFSSGKKIIDSVMRHGVPTAAAINAQAAPSLMELTAQFDAMFPSFLAR
Protein: Calcium homeostasis endoplasmic reticulum protein (D3ZAX5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- U2 snRNP-associated SURP domain containing
- Splicing factor 45
- ATP-dependent RNA helicase DHX15
- PHD finger-like domain-containing protein 5A
- Poly
- Ribonucleoprotein PTB-binding 1
- ATP-dependent RNA helicase DHX8
- Probable ATP-dependent RNA helicase DDX46
- Sin3A associated protein 130
- Small nuclear ribonucleoprotein polypeptide A'
Sequence:
MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQAPELEPTSAMPPLPQPPLAPTASLTPAQGTPSMDELIQQSQWSLQQQEQHLLALRQEQVTTAVAHAVEQQMQKLLEETQLDMSEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHWALTRGRSLPHSQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQSLKTQHEEFVSSLAQQQQQQQQQQQPPQQPPQPQIQLPPMEADVKATPPPSAPPPASAPAPTIPPTTQPDDNKPPIQMPGSSEYDTSAGVQDPAAAGPRGPGPHEQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDPNWNNQFEGPWNNQHEPPPWGGAQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPADMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSHSRSKSRGRSSSRSSSRSSKSSRSSSRSRSRSRSRSSSRSRSRSRSRSRSSRSRSRSRSRSRSKSYSPGRRRRSRSRSPTPPSAAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDEFSTFGARKEEKED
Protein: Coiled-coil domain containing 137 (I3L0U5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAVLQWTSVTAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRK
Protein: SAP domain containing ribonucleoprotein (F8VZQ9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATETVELHKLKLAELKQECLARGLETKGIKQDLIHRLQAYLEEHAEEEANEEDVLGDETEEEETKPIELPVKEEEPPEKTVDVAAEKKVVKITSEIPQTERMQKRAERFNVPVSLESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEVKIYLERFIDLEGKLE
Protein: Pleckstrin domain-containing protein (Q54DW7)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- PH domain-containing protein
- RCR-type E3 ubiquitin transferase
- BAR domain-containing protein
Sequence:
MDTKNKEILGSTIKAWIGRKRYKTMMVNKTNRDKVAKEILDTEQIYVRNLETIVQFYLKPLRNINPPLLSPKSIQIIFGHIEDLLSLNTELLTSIQDRMTTWYQDKRLGDIFTKMAPYLKVYTEYCGNYDKAVARLKQKSDESRDLQMFLKRVTSENSFGLDLNSLLVTPIQRIPRYKLLLQSLIQLTPVEFSDYPTLAKALENVALVADHINESIREKQNSEKILTIQKRFTGQCPPLLAPLRTFIREGSLTKVCRKDHKKRWFILFSDALVYGNRIDTAVGNPIYKFHRLLPLSNTKIANLDDTKHKNSFQLIHPIKSFTLIADTEQEKSSWMNSFSDAQNFLLRNEGSVARMNKQYRSINILKPKEEETVSTAPVWIPDSEAIQCMECTIKFTTIRRRHHCRRCGNVVCGKCSEQKWTLDQYKKDARVCKTCYNYLSISSSRSNENNVSSSNNLSTPTSTFTATTATATAPFGTLTDGASLADVSSDSEGEDNSSSINDSNPDMPIINGLSSIQIDNTPVILNTVNPSPPLLSQPQPQQPQQPQLQPLQQPLQQPPQPPQPPQTNHKSFIATHTAYNKENSLKSTSPSSSFIETSTSTSASTSTSTSTSTSTSTSTSTSTSTSTSNSTSNSTLTPGPPMLSKSNAGNSSLLDFCKSYIQNSPNVSPAKVEKHKHSSSSSSASNSPMQSRTNLDIPSTTTTSTSKGSISPTQSSESIVLPELKPITHDPLVTSNNSSSTLKVNQPIQHTNSSSKLNVIVSTPQTTQTTENNVNNTNTNTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNSDVSSPKPTTKSLPPTPPTKKLPPTPPPKPLPPQPTLPQQPTLPPQPNLPPQPNLPPQPNLPPQPNLPPQPNLPQQPDLSQPPPQQQQQPTLDQAPPRPPKPNQDSRSQSFLCISSTVNSTPPTPPPKRIISTHPANTSFIYQPQQYVSSPNINNVPPPLPPPRIKSQAPIQRD
Protein: Putative pseudouridine transporter (P33024)
Organism: Escherichia coli (strain K12)
Function: Could be involved in pseudouridine transport.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Pseudouridine kinase
- Pseudouridine-5'-phosphate glycosidase
- Uncharacterized protein YjjI
Sequence:
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETPPKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
Protein: Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) [Cleaved into: Ferritin heavy chain, N-terminally processed] (P19132)
Organism: Rattus norvegicus (Rat)
Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P19130}. Lysosome {ECO:0000250|UniProtKB:P02794}. Cytoplasmic vesicle, autophagosome {ECO:0000250|UniProtKB:P02794}.
Interaction partners:
- Ferritin light chain 1
- Cyclic AMP-responsive element-binding protein 1
- Nuclear receptor coactivator 4
- Transferrin receptor protein 1
- T-cell immunoglobulin and mucin domain-containing protein 2
- Small ribosomal subunit protein uS14
- Ferroportin
- Phospholipid hydroperoxide glutathione peroxidase
- Translationally-controlled tumor protein
- Iron-responsive element-binding protein 2
Sequence:
MTTASPSQVRQNYHQDSEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMRCALHLEKSVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKSIKELGDHVTNLRKMGAPESGMAEYLFDKHTLGHGDES
Protein: alpha-glucosidase (EC 3.2.1.20) (Q8SYR7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MVQDEKAAHADGADEQMLGSNGVEDKLAERRDEVKFIKGDHQNGDAKIDIGTVNGGKPAFTGMSKEELMKYANDPFWVRLRWIFFVCFWAIWVGMLVGAILIIIGAPKCAAPQPLPWYKRGPHAKFASVETCRPEDVQVAKKLVSAGAIYELPAALTYDVKKPEVEEKIKHLVALYQGSDTRVILDLTPNYAAKNSQLVQDAIANPEKRSAFVWVSGGKALPNNWLKVGGNRSAWEKVGDNYVLSQFEDGYYDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKNTKFFALFDSLEDEQISSSPKDFSLGPNEYGFYSHRQTTFLSGLGDVLYDYLSIVKNASDEAFFSVAEDVMEPQVYQLSGDSGAYGIDLPMYGNFVKVLSKSKPDTSLQKELDNTLAQSGTDSWLQWNLADVYVDTPQDPSALAMFLSLLPGVPVVAVDAVAYQNVTEETYRQITSLRKTASYMHGNLNLYQADPLVAFSRIKSGNPGYFVIFNPTELPQASNFTIPDNLPDKMTVSYFSGQYNNNMDNSGKVAHAGRVNLKDLKVAPHSSIILTYVPVKAE
Protein: Histone-like protein p6 (Double-stranded DNA-binding protein p6) (Gene product 6) (gp6) (Nucleoid-associated protein p6) (Protein p6) (P03685)
Organism: Bacillus phage phi29 (Bacteriophage phi-29)
Function: Histone-like nucleoprotein that binds to the viral dsDNA and responsible for wrapping and compacting the viral DNA about 4-fold. Forms a nucleoprotein complex in which the DNA adopts a right-handed toroidal conformation winding around a protein core. Binds ito most, if not all, the viral genome, although with different affinity, the highest one corresponding to the genome ends. The formation of the nucleoprotein complex at the genome ends, activates the initiation of viral DNA replication. The binding of p6 would recruit the complex formed by the TP and the DNA polymerase to the origin. Protein p6 also represses early transcription from promoter C2, and, together with protein p4, represses transcription from promoters A2b and A2c and activates late transcription from promoter A3. Protein p6 is therefore involved in the early to late transcription switch. The formation of the nucleoprotein complex at the right end of the phage genome where the early promoter C2 is located affects local topology, which may contribute to the promoter repression.
Interaction partners:
Sequence:
MAKMMQREITKTTVNVAKMVMVDGEVQVEQLPSETFVGNLTMEQAQWRMKRKYKGEPVQVVSVEPNTEVYELPVEKFLEVATVRVEKDEDQEEQTEAPEEQVAE
Protein: Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (A0A024R6K8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ
Protein: Non-classical export protein Nce102, putative (AFU_orthologue AFUA_2G01590) (Q5AVJ7)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGFRGIQLGLRVWQFIWTLLVMALIGNMIAQSFAGNPATINYTMFVAAFSMFTLFYLFPASWNIDWAIHPIILVTLDTLNMIFFLTSAIALAARLECHSCSNQEYILNNEITNGSHNPEKRCREAQASTAFLWFAWAGYAASWVISILQSRRAGANLRPRVGPARGARPSMAQV
Protein: Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Solute carrier family 6 member 11) (P48066)
Organism: Homo sapiens (Human)
Function: Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA). Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P31647}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Sodium- and chloride-dependent GABA transporter 2
- Putative protein CASTOR3P
- Gamma-aminobutyric acid receptor subunit delta
- Muscleblind-like protein 1
- Alpha-tocopherol transfer protein
- Gamma-aminobutyric acid receptor subunit alpha-5
- Twinkle mtDNA helicase
- CUGBP Elav-like family member 1
Sequence:
MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
Protein: Annexin (A6MUT1)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
SDEEVIRIVTTRSKAQLNATLNHYNTAFGNAINKDLKADPEDEFLKLLRAAIKCLTVPEKYFEKVLRQAINKLGTDEWALTRVVATRAEVDMVRIKEEYQRRNSVTLEKAIAGDTSGDYEKMLLALIGAGDV
Protein: SURP and G-patch domain-containing protein 1-like protein (Splicing factor 4-like protein) (SF4-like protein) (Q94C11)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DNA-damage-repair/toleration protein 111
- RNA-binding motif protein 25
- GPI ethanolamine phosphate transferase 3
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH3
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH2
- RNA helicase
- RNA binding
Sequence:
MDKGAPPSIFVNDGSFMERFRQLQQEKDKDKDKVVQVEDSKPVKIISNPKPAANKISIGLKPNDAQKKGGKLAFSLKQKSKLLAPPVKLGTEEDEDDEDVKHEQGFGSVKRQKLEQRDTPVKSAKVSDVAPPPPSDPTVKKVADKLASFVAKHGRPFEHITRQKNPGDTPFKFLFDENCADYKYYVFRLAEEEKLISQTKDSGVLHSGDAGSRTSTAAIPLQKPAYQQTGYQIPASALYDTPVEPGASSRSAQASITRPSDSDSFSGPRGADPLSMMEFYMKKAAQEEKMRRPRQSKDEMPPPASLQGPSETSSTDPGKRGHHMGDYIPLEELDKFLSKCNDAAAQKATKEAAEKAKIQADNVGHKLLSKMGWKEGEGIGSSRKGMADPIMAGDVKTNNLGVGASAPGEVKPEDDIYEQYKKRMMLGYKHRPNPLGNPRKAYY
Protein: Ferrioxamine receptor FoxA (Q9I116)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell outer membrane {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004571, ECO:0000256|PROSITE-ProRule:PRU01360}.
Interaction partners:
- Anti-sigma factor FoxR
- Ferric enterobactin receptor
- Protein TonB
- ECF sigma factor FoxI
- Probable transmembrane sensor
- Second ferric pyoverdine receptor FpvB
- PepSY domain-containing protein
Sequence:
MTATAVVLRNAPSSLDFPRASRLSRSVRAALLSLAMAAGAAPLCASAAEAAAEQARPYAIPAGQLGDVLNRFAREAGITLSATPAQTGGYSSQGLRGSFTVQQGLARLLADTPLEAEDQGDGSFVLREAPAKDGDVLNMQAVEVFALGNNLGSTDGYLATHSQIATKTSKPLLETSQTVSVITREQIDDTASKTVQQAMRYTPGIFTGQVGASNRYDYVVMRGFADNSVDNIYLDGLKAMGDSGTFSSMQVDPYFLERIDVLKGPSSVLYGRSLPGGLVALTSKKPLYEDYRQITGSIGNMGQKEMGFDFSGPLDEEKRIAYRLIGLGKGSDTQFDHVKEERYAIAPTLAIDFSDDTTLTLQGYLQHDPNGGYHGGVPADGTLSHHNGRHISREFFDGEPSKDDFDRTQRMFGYQLEHRIDDVWSARQNFRYLDSDVDLSQVYAYGWSASEPNKLNRYFSGAREHLQAYIVDNMLQAEFATGAARHTLLTGLDYQRRRTVVDWRSGSASALDAFNPVYGDDAISYFPDDNHTRRLEQTGVYLQDLIDIDQWRFSLGLRQDWVSVTDKNRSTGSKADDDWEKFTGRIGALYLFDNGLAPYVSYSESFNPNAYSDASGTPLAPTEGKQWELGLKFQAPGSNSFYTASLFHITQENVASKEPQDNFYTSVGEVRSQGLELEAHTQLSDNLKLLGSYTYTDITYTKSLDGNQGHTPNQAPKHMASLWADYAFDAGPLSGLSIGGGARYVGETWADKENTLRVPDYTLVDARIGYDLGKLGLKGLDVSLNANNLLDKDYVASCYSLDFCYFGEKRNVTATVNYQF
Protein: Superoxide dismutase [Cu-Zn] 1 (EC 1.15.1.1) (Q55GQ5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Interaction partners:
- Probable copper chaperone for superoxide dismutase
- Catalase-A
- DNA-directed RNA polymerase III subunit
- Sphingosine kinase A
- Catalase-B
Sequence:
MSKTAVCVIKGEKVNGVVKFTQENKDSPVTVNYDITGLEKGEHGFHVHAFGDTTNGCVSAGPHFNPFGKNHGAPSDEDRHVGDLGNIVADGESNTKGTISDKIISLFGEHTIVGRTMVVHADQDDLGKGGKPDSLTTGAAGARLGCGVIGVSQ
Protein: NAD-dependent protein deacetylase sirtuin-2 (NAD-dependent protein defatty-acylase sirtuin-2) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2) (A0A0A0MRF5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}. Midbody {ECO:0000256|ARBA:ARBA00004214}. Myelin membrane {ECO:0000256|ARBA:ARBA00037844}.
Interaction partners:
Sequence:
MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQGRGLAG
Protein: Voltage-gated potassium channel regulatory subunit KCNG3 (Potassium voltage-gated channel subfamily G member 3) (Voltage-gated potassium channel subunit Kv10.1) (Voltage-gated potassium channel subunit Kv6.3) (Q8TAE7)
Organism: Homo sapiens (Human)
Function: Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12060745, ECO:0000269|PubMed:19074135}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:12060745}. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane (PubMed:12060745). Colocalizes with KCNB1 at the plasma membrane (PubMed:12060745, PubMed:19074135). Retains in the endoplasmic reticulum in the absence of KCNB1 (PubMed:12060745). {ECO:0000269|PubMed:12060745, ECO:0000269|PubMed:19074135}.
Interaction partners:
- Ubiquitin-like protein FUBI
Sequence:
MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSTEFLN
Protein: Large ribosomal subunit protein uL29z (60S ribosomal protein L35-1) (Q9SF53)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL38z/eL38y
- Large ribosomal subunit protein uL22z
- Large ribosomal subunit protein eL24z
- Large ribosomal subunit protein eL27x
- Large ribosomal subunit protein eL28y
- Large ribosomal subunit protein eL13x
- Large ribosomal subunit protein eL24y
- Large ribosomal subunit protein uL22y
- Large ribosomal subunit protein uL30y
- Large ribosomal subunit protein uL1z
Sequence:
MARIKVHELREKSKSDLQNQLKELKAELALLRVAKVTGGAPNKLSKIKVVRKSIAQVLTVSSQKQKSALREAYKNKKLLPLDLRPKKTRAIRRRLTKHQASLKTEREKKKEMYFPIRKYAIKV
Protein: Caltractin, putative (Q38AR5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA-repair protein, putative
Sequence:
MSSLDSVREDILDVFHIFDEDGSGSITMQELKRAIYTITGIRISRIDLSILVRTCKEEMLKESARKSEAGANVAGKAGEKLWTPEPESEVNTVDPQLFAAVVLKTLNRRTQEQELLFTFRLLEDKDYPGFITKDSLKRASADIDEHLTDQEVNEMFDKLVTGVSAAAIDFVTFSSLMETLRKSI
Protein: Wrapper protein (Q9XZB7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTPHMCSVVRCLLAALILGQVQAELDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRYVRWHRDDVALVDSRHPELPPPDRIMLWPNGSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVIQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSVDTYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQSSTSHVLVWQTESLLPIMEFKLKFRQIPSNNVTRQVRTNWTELTIPAQATNGLIYITTYTLHGLQPASLYEVSVLARNSFGWSDNSKIVRFATGGEVELPNYSTESELQDDLTEEDFHNEITQRSEVLSASMMFNSGSVNGRGGISAFIYSLCFINILRLIS
Protein: Alcohol dehydrogenase 2 (TcADH2) (EC 1.1.1.144) (EC 1.1.1.347) (Trans-chrysanthemal synthase) (EC 1.1.1.-) (A0A2I7G3B3)
Organism: Tanacetum cinerariifolium (Dalmatian daisy) (Chrysanthemum cinerariifolium)
Function: Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide. Mediates the conversion of trans-chrysanthemol into trans-chrysanthemal.
Interaction partners:
Sequence:
MSLNTPDVIICKAAVVRELGRSVMVEEIKVDPPKATEVRIKMLFASICHTDMLCFDGFPTPLFPRIPGHEGVGMVESVGEDIKTKLKPGDIVMPLFMGECGQCLNCKSKRTNLCHAYPLTLSGLLLDGTSRMSIAKTEETIYHHLSCSTWSEYMVIDINYVLKIDPKMHLPYASFLSCGFTTGFGAPWKETQITKGSIVAVFGLGAVGLGAIKGAQMQGASIIIGVDINENKAAKGKAFGMTHFINPKDHPNQLVSDMVRDITDGLGVDYCFECTGIASLLKEIIEASKIGFGTTILIGAAPDNVPISSLSLINGRTLKGTTFGGVRTRSDLPIILQKCMNEEIELDELMSHEIRLENIHEIFEILKKPDCVKILINFD