wanglab/gogpt-training-data huggingface dataset:
Protein: Gram-negative bacteria-binding protein 2 (Q9VVR4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the recognition of invading microorganisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q9NHB0}.
Interaction partners:
Sequence:
MRWEFLPCLLLLISNNKIFGFKVPSINFEMLKDEGFEVSIPDEPGIQRVFYMFQIDDTCPALMDYITEAVNGSWVSKQKMSLQNNDKLQISMLVQFNEEIFEKSETRVIINTRLLTTKDSSSRGITFLTGEGECQAYLAPAQQAKRCKAAQTIVSNGRHTCQGELIFEDNFSEAQLNKTTWKHDIRQRMYHVEEELVAFDDAARNCFVKEGELHIVPTIATEVTDGSFKLGDRCTAVESPEQECNIAHGIFYSIKPPVFSAQIHTRNSFSFKFGKIVVRAKLPKGDWLFPYLMLQPVSTYAETHYAKQLRIAYARGNANLRTKQGDDISGNHLYGGGVVWHHGNAVQFLKDKISNSHYGDDFHNYTMIWQRDKITLMVDDEVYGELYDGLPFFNEKCFIIFGVTVGGFLNFDDSLLAKDVKPYKNREPRAALSFWQHRDAWAPTWGRHSAMVIDYVRVYAE
Protein: Chymotrypsin-like elastase family member 1 (EC 3.4.21.36) (Elastase-1) (P00772)
Organism: Sus scrofa (Pig)
Function: Acts upon elastin.
Subcellular location: Secreted {ECO:0000269|PubMed:4578945, ECO:0000269|PubMed:5415108}.
Interaction partners:
- Alpha-1-antitrypsin
- Carboxypeptidase A1
- Carboxypeptidase B
Sequence:
MLRLLVVASLVLYGHSTQDFPETNARVVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN
Protein: SET domain-containing protein (Q57UB6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MESVSLIQLMLQEEGAFFHPSIGVLPIHQMGGGHGVIATENLPSNTVIVKIPESSMITAQKARNHLNFWISQQKQERLGWTPFDGRSRRETSVDILGDLDQMLSPGSMIIFSLLVAAGQCGRFSNNAFHKKAGSASEVMFTVSTGGGNADLGPFFIHRWMRTWLLSLPTKYDNLLELLEHTHLDSTCVGVARSHDCEGGGACLRNFLCFERHRRKVLEERMQLEKEFNIVMSILSLHLPLVQPSGGCTMSCATPFTMQQFIWAYNTLMSRGFSYDPEVWAVIPWVDYFNHSLTNNATMRFDRCMGAYIFVTTAPVSKGDQVFLQYGSYTDAELVLWYGFITTPSLLPKFSSNDDIRSRMSLLRKVLLEHLRHEEVGNLGSERDAWLSSLNTALGHCFSPWAKADGSYPPSKKGASWLESLFTSYKDAVAGHKAFDVSGNVHTAVKAADELCRVLTRGTVVWDHRRLTEPGCTVGVWAPSNSMLSLLKYVSRVCRKFSPDTCLVPTAVLRAICWAELVCNGIVGEFDCPVDALLCPFGPKNEMVPLSEGHVGNMARQVSVDAAYLLYFLAVEATEDELRVYFLHDCV
Protein: Multiple RNA-binding domain-containing protein 1 (O13620)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in pre-rRNA processing.
Subcellular location: Nucleus {ECO:0000269|PubMed:10759889}.
Interaction partners:
- Ribosome biogenesis protein bms1
- U3 small nucleolar ribonucleoprotein protein imp4
- Ribosome biogenesis protein ytm1
- Periodic tryptophan protein 2 homolog
- Pescadillo homolog
- RNA cytidine acetyltransferase
- Uncharacterized protein C4F10.09c
- Ribosome biogenesis protein enp2 homolog
- Ribosome biogenesis protein erb1
- Uncharacterized NOC2 family protein C1142.04
Sequence:
MSRIIIKNIPRYYDKEKLSTYLKSLPQLDAEITDVSVAKTKEGVSRRFAFIGFKNEEDADKAIRYLNKSYVETSRIEVHRALDYRSANEKLRPYSKYASKNIELKLQKKEKEEELRNLEEEKAKKKKDANLKRKFLDTLDPKAREFLKLSSSISNSRSWENEEVFDTEITNPVIPADEDDDEYQDLPAAKRHEGDSIKSTEHDSTLDSGVVIDGREKSSSELHEEESEQAAEGDTAKNSGTDAQAPLSDDEWLRLHRTRIKEKQPEEEVSVVGDELKSFDKENNDEHLERVTNDKIADASMLQKAENNVSEQERNIQLISETKRLFLRNLTYSCAEDDLKSLFGPFGQLEQVHMPIDKKTNNPKGFAYIDFHDADDAVRAYLELDAKPFQGRLLHVLPAKARSSILLDDYALSKLPLKKQRELKRKNTAASSTFSWNSLYMNADAVVTSLASRLGVKKTDILDPTSSDSAVKQALTETHVIQETKNFFEEHGVDLDAFKNAARSDNVLLVKNFPYGTSAEELTSLFSPFGELGRILIPPAGTIAIIEFLNAPDCRQAFSKLAYTRIKSSILYLEKAPRDVFTTSFKQSGKPELAQKVNAVEATTSEKVGTEDIESLDTATIYVKNLNFSTKQEEFQKVFKPLEGYLSAVIRAKPDPKRPGKYLSMGFGFVEFKDKASAVAAMHAMNGFVLDGHKLEIKLSHQGVDAAAEVRKQDSSKPKGTKILIKNLPFEATKKDVQSLLGAYGQLRSVRVPKKFDRSARGFAFAEFVTAREAANAMRALKNTHLLGRHLVLQYASNATMDDMQHAIEKMAKEANAEAAAPSITGKRLIETD
Protein: Secreted protein (Q388J4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLWGSRKGRRERSIWDLRRWTCSCAARTLLGCVKSAAVLMVLWRHGFAPSTVGPFRTRTMRVWLARVRGAGAVALGWDNLLLGSGGGRQRKGMDDGPIGVHRLSLCCDPSCNTGMSASCSFPFFCLSACL
Protein: 2Fe-2S ferredoxin-like superfamily protein (F21O3.19 protein) (Uncharacterized protein At3g07480) (Uncharacterized protein F21O3.19) (Q9SRR8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Gamma carbonic anhydrase 2, mitochondrial
- Gamma carbonic anhydrase-like 2, mitochondrial
- Gamma carbonic anhydrase 1, mitochondrial
- Acyl carrier protein 2, mitochondrial
- Acyl carrier protein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8-A, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Uncharacterized protein At2g27730
- Excitatory amino acid transporter
Sequence:
MATTLQKLSSQIHRLSPFTRSLIVRTSATSAPSPSLGSKKVSDRIVKLSAIDPDGYKQDIIGLSGQTLLRALTHTGLIDPASHRLDDIEACSAECEVQIAEEWLEKLPPRTYDEEYVLKRSSRSRILNKHSRLGCQVVLTQELQGMVVAVPEAKPWDIP
Protein: Two-component regulator (Q0PBF4)
Organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Interaction partners:
- FIST domain-containing protein
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- Chemotaxis protein
- Methyl-accepting chemotaxis signal transduction protein
- histidine kinase
- histidine kinase
- MCP-type signal transduction protein
Sequence:
MRILVIEDEISLNKTIIDNLNEFGYQTDSSENFKDGEYFIGIRHYDLVLANWTLPDGDGAELVNTIKHKSPRTSVMIMSSKTDKETEIKALKAGADDFVKKPLDFDILLARIEARLRLGGTNVIKIEDLVIDPDEEKITYKGQDIELKGKPFEVLTHLARHSDQIVSKEQLLDAIWEEPELVTPNVIEVAINQIRQKMDKPLNISTIETVRRRGYRFCFPKKS
Protein: U2A'/phosphoprotein 32 family A C-terminal domain-containing protein (Q385P9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MVYESESCRNITSAEDRGRASSVVVEHLRAAIVQAMKSSETAELVALICDNNGLTVEEFLQAPHEFTEMELFLLATPQLPQLRLFPYLTVVKVMHVGLESMEPFSPLHHIEELWLCDNNITVIEGVRQMRSLKYLYLQGNLIESMDGIPSLPNLERLWLCRNRLQNIRKLDLLPQLRSLWVASNRITSLEGAFDSSMTALEELNLSNNQIYFFGQIKNLSVLKSLRVLWLSDPMYGDAPIYHLSNYTTFSLQHLPHLEQLDGVSITMEQRSLTVSVYAKKSIYYSMRGAILNGNVALMYKFAQQEAEKKRNFARDAIRRLDIQLMKLGEYGRDGQYVSRVVTAEEEAHRQTLKRARETREVELEGIERQLLEAWSRTTFETESLHERLLLELNSCGSIRLEEGSEADSWYVNAGELLTSRFDADLYEGMGVTGVKVNRVFRITCQGLRERFDNRIRELDVDLADTRNRRALIRLFSAIPRHAKDQRSFLYEVMTNGFPGLYAEDEGVPLTNSLFYADQERLLSLKRNRNIFGLTSQPDQLSAQLLVSRLFLGKCVAEMGGGRDTSLEEGGDKAVEQPFMTGRRKVTRRHYGDGVFSVYRASEHNPAVKVWHVFDKCLLLPEYVIDFTYTTKAHLTISPPLSMYDKRESLQALLDKVMPMGAQDAINDARTAGYPLLHFLHWLDSNAFHVYSSGETEKAISRAKELYQPKHGLMLINGPLTNELVDSYISNYGTLSDSMLTYCDISEKQIHCIPESLTTSAWGALKTLLLHHNKITTVAWEALANAAPTLETLDLGNNEIARIDLGAASFPGLKKLCLSFNSCSAMDDLRQLPAKMPELCCLHIDHNPWMMNKVVEPFCVSIMPELQQLNGIAISRHARLSYLRKRTLMLNQSTLQYIVSEEQKLRAESATEAFPNSGCGNVLDDSSSSNNNNSDVFRSRYFEQVIANMADRVNQDRPFAPTAGKELSGPPLRSVRAFSFHSSLSSDIKWVTLLPQLRHLSLTSHLIEDISPLAQLRHLRTLNLNDNLVNSTKPLEGMRLISLDLSRNCLYEVDGIASLCDLRFLSIRQNFITSVTELQNCLSLEELYLADNNVPDVRELCLLQSLPKLVSMDAAGNLCAERENAEKLTEYRDCLLYNMPKLKVLDGLPVAEADQQRARDVFAGRVSADLLIERVGPVEMWGTAQEVDLSHCGLRELTLLDPFSCLRVLHLHHNNLERIDGLSSLTSIVALDLSHNRLGHCAVGRVLRNLPNIHSLSLEGNHITDVSALSLALPRLQFLNLKGNEISSIETGLQDLPALRELLLDNNKLRALGPDCFANNHQLTDVSADENYIRTIDGLQSLPRLSILSLGSNRLGDIRAIAQVLRHSGCLAAATFIGNAVARKPPYRVHMIAALPTLTTLDHREITDDERERAELMRNAEIGTPHNVVLDTTFPAEAVGGARASAPVGTLRSIVLHSHRFPAPATPRLQLPVCKNPRGEQHGREGVGKGFAPRLHGAR
Protein: Ras association domain-containing protein 9 (PAM COOH-terminal interactor protein 1) (P-CIP1) (Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor) (O88869)
Organism: Rattus norvegicus (Rat)
Function: May play a role in regulating vesicuar trafficking in cells.
Subcellular location: Endosome {ECO:0000269|PubMed:9837933}. Note=Accumulates on perinuclear endosomes.
Interaction partners:
- Peptidylglycine alpha-amidating monooxygenase
Sequence:
MAPFGRNLLKTRHKNRSPTKDMDPEEKEIVVWVCQEEKIVCGLTKRTTSIDVIQALLEEHEATFGEKRFLLGKASDYCIVEKWRGSERALPPLTRILKLWKAWGDEQPNMQFVLVKTDAFLPVPLWRTAETKLVQNNEKPWELSPANYMKTLPPDKQKRIVRKTFRKLAKIRQDTGSHDRDNMECLVHLIISQDHTIHQQVQRMKELDMEIEKCEAKIHLDRIGNDGADYVQEAYLMPRSSEEEQKLDFQSEDNQTLEDLNDGEGVSQLEEQLQYYRALIDKLSAEIEREVKGAGTDGSEDMEGAAACELENSDLESVKCDLEKSMKAGLKIHSHLSGIQREIKYSDSLLQMKAREYELLAKEFSSLHISSKDGCQGKENRGKEAEASSSNGEIPPLTQRVFNTYTNDTDSDTGISSNHSQDSETTLGDVLLLAT
Protein: Expressed protein (Serine/arginine repetitive matrix protein) (O64572)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- SAGA-associated factor 29 homolog B
- SAGA-associated factor 29 homolog A
Sequence:
MSAPGKFDYSSGGLDRPLYRSNFAAQMERSSSFRESMEHPVPSHPIMLRTTSPIAQTDVTNFFQCLRFDPKVVAADHKSIRQGDFKRHVSIALGILGDESPSGSLKGKFIPSPIPEEIKRFKAGLRENNVKARERVKIFNEASSVFNKFFPSVPTKKRSRPEGFSGDRSGDRLVSGPGLGKMGIQGQTLAGGFELDQQKLDERPKSGVPNKRTRTSMMDVRNNCIVRQSAAVDKDKEIMRVGNHNAVQGEDRTSTGIDGWETSKMKKKRSSINADCHPNLASNKVVDGYRDLKQGIQQKPTGDSRSRVNGDSNMFRQSAGNGATGYGRSDSLSHQTSLAGHSPLARVDSDHNSLYSEKRERSIVSDKERVNLRGVNKSNIHDEFNSSSLVSNTKTNASVRGPRSGSGLPPKLSPGLHNTPSPIEWDISGCTNKPPTLSGVTQRKRMTSNRSSSPPVTQWASQRPQKISRIARRTNLVPIVSSQDEVPYSDNISDVGCSETGFGFHKRSPAASPQLKLKGESSFSTAALSESEESGHPEIKSKDKGKQSDEVDGKAAQNIPRVSIPALQSRKSNKPAAGEEIGDGVRRQGRTGRGFSSTRSLNPNGVNKLKNVGTAKHLRSARPIFDKNESKVGRPPTRKLSDRKAYKRQRATATNAPTLDFHVGSNDGREELLAAVNSAINIAQNFPNSFWKQMERYFGYISDDHINFLKQQGELSSMGPTPVLTSSEFDSPVFPEELATSRADSKASPLYQRLLSALISEDSMGVNEDLQVDLDDDSEFSVLNNMEFNGFRNNERLELDESENDGSAILFKGVDKSAHHCNGKFPDNSPIDFVDIQYDKLGIDEKIYLEAQSLGISIDLMPSISNVEDEGIADEIKKLEEAICNEGSKKKEIVDRLLKPAIEMKELQEKELDQLGYEKLIEMAYEKSKASRRHHNAGGKNSNNKISKQAALAFVRRTLERCHQFEKTGKSCFSEPEIKDMFIAGLATAEDTLMDKEYNTSTSTPMGSQPSSSLALIGQNSENYAKSSDVLPSENALLEQTTGKEDTAWSNRVKKRELLLDDVGIGTQLSSNTKGKRSDRDRDGKGQASSRGGTNKIGRPSLSNAKGERKTKAKPKQKTTQISPSVRVPEQPKPSLPKPNEANSEYNNLEALEETEPILDLSQLQIPDGLGDFDAQPGDINSWFNMDDEEDFDMTELGIPTDDISELNIKL
Protein: Chromosome segregation and cytokinesis defective protein 1 (O45952)
Organism: Caenorhabditis elegans
Function: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis during mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. In the complex, it may be required to direct the Aurora B/air-2 to centromeric DNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:12707312}. Chromosome, centromere {ECO:0000269|PubMed:12707312}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:12707312}. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the central spindle from anaphase through cytokinesis.
Interaction partners:
- Chromosomal passenger complex protein bir-1
- Aurora/IPL1-related protein kinase 2
- Kinesin-like protein klp-19
- Incenp-like protein ICP-1
- CNH domain-containing protein
- SET domain-containing protein
Sequence:
MPPRKIKKDPAVVAMADTLETRVKDLLEEYKKKLREVALQTAKAESDRIIATIKPKYRDMPIMEFLASPPDDFYIESGEEEEEGEAAVAVKQELPSEPDMEIDDAAAAQKTSIPIGQNSGRNTVQVKQEPEIDDDAAHETSIPIAPSGQNSGRNTAADEHRRNEIITPAGQVLPLPTLQPEKPFRAPHVDEEIAFSVNGSPLVLAGRTTATAAGKENRKKSKKSGAASKKAAAAAGPLQPETENAGTSV
Protein: Vesicle-associated protein 2-1 (Plant VAP homolog 21) (AtPVA21) (VAMP-associated protein 2-1) [Cleaved into: Vesicle-associated protein 2-1, N-terminally processed] (Q9LVU1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in vesicle trafficking.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- RING-H2 finger protein ATL75
- Endoplasmic reticulum vesicle transporter protein
- RNA-binding
- Calcium-binding EF hand family protein
- At5g57460
- Transducin/WD40 repeat-like superfamily protein
- Protein indeterminate-domain 11
- Transducin/WD40 repeat-like superfamily protein
- Calcium-binding EF hand family protein
- AP-2 complex subunit sigma
Sequence:
MTGVGENQLISIQPDELKFLFELEKQSYCDLKVANKTENYVAFKVKTTSPKKYFVRPNTGVIQPWDSCIIRVTLQAQREYPPDMQCKDKFLLQSTIVPPHTDVDELPQDTFTKDSGKTLTECKLKVSYITPSTTQRSSESGATNGDGQSSETISTIQRLKEERDAAVKQTQQLQHELETVRRRRNQRNSGNGLSLKLAAMVGLIGLIIGFILKLTLASPT
Protein: Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19) (O95881)
Organism: Homo sapiens (Human)
Function: Protein-disulfide reductase of the endoplasmic reticulum that promotes disulfide bond formation in client proteins through its thiol-disulfide oxidase activity.
Subcellular location: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:12761212}.
Interaction partners:
- Peroxiredoxin-6
- Glutathione S-transferase A3
- Glutathione peroxidase 7
- Glutathione S-transferase 3, mitochondrial
- Glutathione S-transferase Mu 4
- Glutathione hydrolase 6
- Glutathione peroxidase 3
- Probable glutathione peroxidase 8
- Glutathione hydrolase 7
- Epididymal secretory glutathione peroxidase
Sequence:
METRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDPSGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL
Protein: Tribbles pseudokinase 3 (J3KR25)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
Protein: Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) (Q9Y2G3)
Organism: Homo sapiens (Human)
Function: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes. May contribute to the maintenance of membrane lipid asymmetry in endosome compartment.
Subcellular location: Recycling endosome membrane {ECO:0000269|PubMed:21914794}; Multi-pass membrane protein. Early endosome {ECO:0000269|PubMed:23585472}. Endoplasmic reticulum {ECO:0000269|PubMed:21914794}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:23585472}. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B (PubMed:21914794). In the presence of TMEM30A, mainly located in recycling endosomes (PubMed:21914794). {ECO:0000269|PubMed:21914794}.
Interaction partners:
- Cell cycle control protein 50A
- Cell cycle control protein 50B
- Phospholipid-transporting ATPase IH
Sequence:
MWRWIRQQLGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGIKCLDSMCCFPEGEAACASVGRMLERVIGRCSPTHISRSWSASDPFYTNDRSILTLSTMDSSTC
Protein: Cystatin E/M (Cystatin M/E) (Q9D1B1)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Legumain
Sequence:
MERPHFPLAMGLGLLAFCLLTLSPDARAELRSRRTGERQNLSPTDPRVQKAAQAAVASYNMGSDSLYYFRDTKVIDAKYQLVAGIKYYLTLDIESTECRKTRVSGEHMDLTTCPLAAGGQQEKLRCNFELLEVPWKNTTQLLKHDCVQV
Protein: Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40) (Q8R016)
Organism: Mus musculus (Mouse)
Function: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q13867}. Cytoplasmic granule {ECO:0000250|UniProtKB:Q13867}. Note=Co-localizes with NUDT12 in the cytoplasmic granules. {ECO:0000250|UniProtKB:Q13867}.
Interaction partners:
- Caspase-14
Sequence:
MNNAGLNSEKVSALIQKLNSDPQFVLAQNVGTTHDLLDICLRRATVQGAQHVFQHVVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPESHTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISSTQDAMMEEIFRVVCICLGNPPETFTWEYRDKDKNYHKIGPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLKNMNKAERLAFGESLMTHAMTFTAVSEKDNQEGTFVKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVLPAWDPMGALAE
Protein: Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol Delta-24-reductase) (Q8VCH6)
Organism: Mus musculus (Mouse)
Function: Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q15392}; Single-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q15392}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- 7-dehydrocholesterol reductase
- Lanosterol synthase
- Lanosterol 14-alpha demethylase
- Lathosterol oxidase
- Methylsterol monooxygenase 1
- 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
- Delta
- 3-beta-hydroxysteroid-Delta
- Delta
- Sterol O-acyltransferase 1
Sequence:
MEPAVSLAVCALLFLLWVRVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALLNSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELILADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICEKFTRESQRLENHFVEGLLYSLDEAVIMTGVMTDDVEPSKLNSIGSYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCMSQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGDEAELYVDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKICKAARH
Protein: Golgin subfamily A member 5 (Golgin-84) (Protein Ret-II) (Protein Sumiko) (Q9QYE6)
Organism: Mus musculus (Mouse)
Function: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Found throughout the Golgi. {ECO:0000250}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 7
- Thyroid hormone receptor interactor 11
- Golgi reassembly-stacking protein 1
- Golgin B1
- Conserved oligomeric Golgi complex subunit 3
- Golgin-45
- Conserved oligomeric Golgi complex subunit 6
- Golgi reassembly-stacking protein 2
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 5
Sequence:
MSWFADLAGRAEDLLNRVDQGAATALRKENTSNIFYSKNTDYPELQQQNTDSNYQTGQKANYISSAADNIRHQKATILAGTANVKVGSRTVGDATHPTEHASAPRPSSQFVRRKKSEPDDELLFDFLNSSQKEPTGRVEVKKEKGRAPVSPSSPSGVSSVNTSVTTTKAMGGNAGSQSPGVNSSDSVPEVHKEPSEESTAPSATSEEHSSTPSDGSSRSQELSNLRLENQLLRNEVQSLNQEMASLLQRSKETQEELNKARVRVEKWNVDNSKSDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQVLSSRTEALEALRSEKSRIMQDHKEGSSLQNQALQTLQERLHEADATLKREQESYKQMQSEFAARLNKMEVDRQNLAEAVTLAERKYSEEKKKVDELQQQVKLHRASLESAKQELVDYKQKATRILQSKEKLINSLKEGSSFEGLESSTASSMELEELRHEKEMQKEEIQKLMGQMHQLRSELQDMEAQQVSEAESAREQLQDLQDQIAKQRTSKQELETELERMKQEFRYMEEDLHRTKNTLQSRIKDREEEIQKLRNQLTNKTLSNSSQSELESRLHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQVHSASSGPNSGSAINMSGVDSGEGTRLRNVPVLFNDTETNLAGMYGKVRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYSPEMHHDQPYGK
Protein: 60S ribosomal protein L6 (Q8TBK5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGEKVEKPDTKEKRPEAKKVDAGGKVKKGNLKAKKPKKGKPHCSRNPVLVRGVGRYSRSAMYSRKAMYKRKYSAAKSKVEKKKKEKVLATVTKPVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHRGKRVVFLKQLASGLLLVTGPLVLNRVPLRRTHQKFVIATSTKIDISNVKIPKHLTDAYFKKKKLRKPRHQEGEIFDTEKEKYEITEQRKIDQKAVDSQILPKIKAIPQLQGYLRSVFALTNGIYPHKLVF
Protein: Protein phosphatase 2, regulatory subunit B'', alpha (Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X2) (B0S5Q0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Protein phosphatase 2
- Protein phosphatase 2, regulatory subunit A, beta a
- F-box protein 28.
- DNA-dependent metalloprotease SPRTN
- Ryanodine receptor 2b
- Serine/threonine-protein phosphatase 2A activator
- Tight junction protein 1b
Sequence:
MMIKEASLREDPDLRGELAFLARGCDFVLPSRFKKRLKSFQQAQIQPEKKPGTPPPTLSPAPSSPTPRPPSPPPAKVVATPPPSSINIPRFYFPKGLPNCAANYDEAIAKIEAAFTEFEEEKADIYEMGKIAKACGCPLYWKSPMFICAGGERTGFVSVHSFIATWRKLLHSCYDDASKFVYLLAKPGCTYLEQEDFIPLLQDIVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWTGKINMTELRRSNFLQTLALLEEEDDINQITDYFSYEHFYVIYCKFWELDSDHDLFIDPKDLARYNDHASSSRIIERLFSGAVTRGNSVQREGRMSYAEFVWFLISEEDKKNPTSIEYWFRCMDMDGDGVLSMFELEYLYEEQCERMEGMGIEPLPFQDLLCQMLDLVKPECPSKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDLDSDGPEPSDWDKYASEEYEILVAEETANEQLREGSFDDDYESDELTVSSDIGNKMDKLVISDLSA
Protein: At2g47310 (Flowering time control protein-related / FCA gamma-like protein) (Putative FCA-related protein) (Q6AWW6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DNA replication complex GINS protein PSF2
- Uncharacterized protein
- F17A9.5 protein
- Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein
- U11/U12 small nuclear ribonucleoprotein 35 kDa protein
- Ubiquitin carboxyl-terminal hydrolase 1
Sequence:
MERRAPNAFPGAPPPVPYYHNNYNNPPHHQIHPPPPPHHHIAAVGFHKYPQNDNRDQRFNQPHYSGQQQNMIVDQSNNAPPPFPPSPCGGSSLRKRRSQSATDNADGSIAKLYVAPISKTATEYDIRQVFEKYGNVTEIILPKDKMTGERAAYCFIKYKKVEEGNAAIAALTEQFTFPGEMLPVKVRFAEAERERIGFAPVQLPDNPKLYVRCLNKQTTKMEVNEVFSRYGIIEDIYMALDDMKICRGYAFVQFSCKEMALAAIKALNGLFTIRGSDQPLIVRFADPKKPRLGEQRSTFNTPPAMQHFDPNWHSQPYPQWENKEPAPPRVVQHHDFSSQPNHFPHQNTQAVSEVHKPLHQDIPPANFEKHQKSETASVETRSDGQKISSHSNAFHEDQNTVSSECDWSEHTCPNGNKYYFHCITCESTWEKPDEYSMYERWLKEQTRLQDEKIKSPPLNNESQEAIENSEQVESDVLQQNGELQQPSLSTADQENNVVVYPVTTLAVETTCS
Protein: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (A0A2R8Y526)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED