wanglab/gogpt-training-data huggingface dataset:
Protein: Myricetin 3'/5'-O-methyltransferase 1 (ShMOMT1) (3'-methyl myricetin 5'-O-methyltransferase) (Syringetin synthase) (EC 2.1.1.267) (3-methyl quercetin 3'-O-methyltransferase) (EC 2.1.1.-) (7-methyl quercetin 3'-O-methyltransferase) (Rhamnetin 3'-O-methyltransferase) (EC 2.1.1.-) (Myricetin 3'-O-methyltransferase) (Laricitrin synthase) (EC 2.1.1.267) (Quercetin 3'-O-methyltransferase) (Isorhamnetin synthase) (EC 2.1.1.267) (F2YTN4)
Organism: Solanum habrochaites (Wild tomato) (Lycopersicon hirsutum)
Function: Flavonoid 3'/5'-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as myricetin derivatives, aroma compounds possessing antioxidant properties and exhibiting pharmacological activities such as anti-carcinogen, anti-viral, anti-thrombotic, anti-diabetic, anti-atherosclerotic, and anti-inflammatory effects. Catalyzes S-adenosylmethionine-dependent regioselective 3'/5'-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates, including myricetin and quercetin, but inactive toward kaempferol. Mediates the formation of 3'-methyl derivatives from quercetin, myricetin, 3-methyl quercetin and 7-methyl quercetin (rhamnetin), producing 3'-methyl quercetin (isorhamnetin), 3'-methyl myricetin (laricitrin), 3,3'-dimethyl quercetin (3-O-methylisorhamnetin) and 7,3'-dimethyl quercetin (7-O-methylisorhamnetin), respectively. Triggers the 5'-O-methylation of 3'-methyl myricetin (laricitrin), thus leading to production of 3',5'-dimethyl myricetin (syringetin).
Interaction partners:
Sequence:
MALSMDNIVISNEEEICMMKAMHLPCGLYLNMVLKAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSLLTCNITKNDDGNVHTTYNLTPLSQSLISDKDGTSIAPFLLLATDPVGVHACFHLKDAILEGEIPFNKAHGVHAFEYHGKDSRMNGLFNKAMQNLTCIEMKRIVECYNGFQGVKEIIDVGGGLGISLASIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMWDSIPQGELIILKAVLHSLDDEDCVKILKNCWRALPNDGKVVVIEQIQPKYPETNLLSKRSFSFDISMMIMFHGGKERTKQQFEDLAKQAGFTYIKVVARAYYSWLIELYKY
Protein: TOG domain-containing protein (Q388R9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 40S ribosomal protein S15, putative
- 40S ribosomal protein S13, putative
- Small ribosomal subunit protein uS5
- 60S ribosomal protein L10, putative
- Large ribosomal subunit protein uL5
- 40S ribosomal protein S16, putative
- 40S ribosomal protein S26
- 40S ribosomal protein S18, putative
- 60S ribosomal protein L27, putative
- 60S ribosomal protein L5, putative
Sequence:
MCLHIREGKVADKQQIKINGGGKKKIVSLSIKPGATINRGTGASNMDIRGVVAAFQRGSPLIPRAVKVLFNYSHPLTEREVALLNQYVKGVQEQQEAGLRTTEVPENINALAARPLQRLPAVSVIQCVLGAAKIPSFPIRYQRQLQRQLLPLVVRDTPLTREEWTSILHQTATLPMGYSRTALRCAEEILKAAAPPLFKGDAVPQAGEEQTLFLNIFATVVLHYAKLHAACRKHSFSSLSLNIPVGNENVLLCGPMRRLRRILEKSCNHLREKWGALIEKLPPPQALTLSVFPSWSCPISKETVQQTVKSSPMLMLHLLGKRPVPGSLLVDKAEEVIQLCLYNMGLTNCSLNSTRDYLTVILALPVSDKRGYFMTHGEDSFFQLLMPFVNKGKILTPEVAQEWETLYCLIFLGIGMEEELLPLFVRAAAAVMQKCCASTEKASIMILTSAVLRASSETSRLRVRQEDIVKIIERDLVSHSADAVKAAWRLLQVSGVENRVVDEMRAALKSAKGNEEVRWAMALYISPKRAPSDVIEGLNELLFDSCEEVDAYRPAAFIALRSLVESKAKVSPKLCTVLCRADVVSRIGESRDELDALAETAVALANVFVFSPMALLLTHRSGLLRRRLSYSVEDLASDASAAIALWDSVTHVVFGLEEKEKTNILSNSACGALLPVASALLKHTAKMAVPTALRELVICCGHDHIQGEDPYYFCDNDSLLGRMRTSSKVVQRRLFDSLFSGEHRHLLVLHHDALVDGLCGYFSESVHLRTAASRGLVLLLGTRTGFASSQIIFNKLLDAVKESVEYMLALDMRDRAIAAASPAAMLQYEEKTLRERQLLKTYPSKPPKGMAEDDFEDMKRRDAAALEKGREELRKEIQKHSRVIEDILLQRKTALVTVRTLGTSGDFPLECVAVLFPYLQETLSGNDVPEVLERLLVDAIAGLLSRTAFAHIAEGMSRTVAELEGKASLSVDDVSRVSTMATYLRQSMTKMLPPPLFVVLLPFSHVAFKAGRGSQAVRTTIPLATQHQIMGVLIQNIGQANLPQPTETLQLLYTILQRFPSLFKSVQQGINLLMAMIPTSHLVALELGFFNQVDTVKEVTAAAYHRFSHFSTCRRALTLAAVFLHDSSTDVVRSMRGITQNSSHPFTLCPTDWNDLTYFLQAYGQQQKHHATRISASMRELFLLPNTTDVQQRSWLKDICKIGGLGSVVAIEVLSSSLKGDAFQDVLLYLCTIVESPNTEPFMLVVLSCGRVVLHDCSLVVLKAMSQTLQVRLSKPPKDITPVHKELYLAISTVWLTIIGCRLKENSLLESIIVQQGSTLNNSTSAMVHRTVCDSMVEVTKNKDACSLPQLDEFVQKCLKQVLHSGSYIKKKAHAYGVAGVLHGLGLTSLRRYNILETMQASMREKQAERSGVMVLLEVLSEVMGPKFEPYALAMSSGLLEGVADKDQKVSECADDASRLMVSSLTAVGLRQLIPRLVKGLAADQAKMRIPPLNFIGYVAFCSPKQLAATLPEITKHINACLFDVNHNVSAAAMNALRRVAGVVSNTEIREHVEVILAALRSPNTETENALDTLLYTRFVNAVDPASLALIIPIISRGLSNQMPHTRPKAAQIVASMVNLVNDTQSLKPYCQQLVSLLEEAAEDPKTETRTTSAKAIAALAAAIGGTLVDEIVAWCFSNLHKSHGSSVEKAGAAQVFVEIVESCGDAVLYDSFAVIETGMLDERPPVREGFLHIVVYAPSTLNPTTFQQLLPMAFPWVLEGLSHFSDRVRDVALTAGSSIINLYGTRNLALVLEPLMNGVLSEVSTLRHSSLLLTSKLLLHIVQNIRKKMRVQSVKERGPEDGEKGGKEDEQTNGEPAADDDTGAMEILQVESARSVEKRGISVLGALEEALGTEGFVRLLSAIFCGRNEHNLNVRTESNNAWQACVASPCGAVKKIFSGLIDLLVIYAPSENPDCAEMANKTIEFTSRLSEMIEPFIDTLCDRYKEDDRRSKLGALTCLTCVVGYVDGRRLIGMGGQIVGCVLPGMQEKDPQVQQCARELFAKVSKIVGPGLIESATEAQLETSVRGVVEVVKVKPNVALEIIFRYLNRQSKYVQHNLELLDTILDVEEADDQMRRYIPDTGKILLAFLVQRLDGASESYQKFIAGLSQGYEHIPQEQWQKALRAPATQLGALAAAEAFGLGISTESVESLSAVFRAAIESLGSDNDEMRALAVSMIPKLFNSIERRIVDSLEEEEQQDLTTSKRAVGRYLLQYLGVFQETLGVTARAMVTDTEPEFSVLGEGGQARLFDSLMAFYNRGLDYGTSMQKVQAVECIQDLLTYAPRRVSAGSTNTVAGRCSKVLFVRNDGGVVLAVVRLCLQLMGYPASGKEAMVEGTMALAMFNAALCDVGEARVLALRVVIQLLQRSERYADLILGTVVAKKGAVDSPLLRGVMCRFISVVMRYSNLSKTLSHITKLMDIVKPIWERAETPATAVAAGIAVAALCRSASITDEQFSTLRDTALNMMSTKGTSALGGFAFSYSVIASRVERVDASFVNAAMFTVRSAAGFGISDKLSVTWILRATAALVGTGLVPTSELKMEVYAPLLRRVDANDEVLMSTSQYFYDAVSAQFPQTISSMSDFHREMSTQWCVVGHFDADLDDEVIADTMC
Protein: E3 ubiquitin-protein ligase Su(dx) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Su(dx)) (Protein suppressor of deltex) (Q9Y0H4)
Organism: Drosophila melanogaster (Fruit fly)
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Down-regulates Notch/N signaling pathway, probably by promoting Notch ubiquitination, endocytosis and degradation. Involved in wing growth and leg joint formation.
Interaction partners:
- Protein deltex
- E3 ubiquitin-protein ligase Nedd-4
- GH01161p
- E3 ubiquitin-protein ligase CBL
- E3 ubiquitin-protein ligase Smurf1
- E3 ubiquitin-protein ligase NRDP1
- E3 ubiquitin-protein ligase NRDP1
- Nedd4 family interacting protein
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MADGNGLPAGAASGGMEAGQTVNGAGSASPTPTSSSGAGASGSANQGYHQLSVTIEEASLRNNGFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITPNSTLHFKVLDHSSFRKDAMLGERIINLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSGELVAILNGLKLDMSKLQIQPVAGQQNGNPPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRSPLPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAVYLPAGGGAAVGPPGVAGPPIEQPGVGLPVSQSTDPQLQTQPADDEPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSLINEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE
Protein: Pyridoxine/pyridoxamine 5'-phosphate oxidase 2 (AtPPOX1) (EC 1.4.3.5) (Q9ZPY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). Has an in vitro catalytic efficiency for PNP approximately 300-fold lower than that of PPOX1.
Interaction partners:
- Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic
- Pyridoxal kinase
- Probable pyridoxal 5'-phosphate synthase subunit PDX2
- Pyridoxal 5'-phosphate synthase subunit PDX1.1
- Pyridoxal reductase, chloroplastic
- Thiamine phosphate phosphatase-like protein
- Inorganic pyrophosphatase 2
- Inorganic pyrophosphatase 1
- Pyridoxal 5'-phosphate synthase subunit PDX1.3
- Pyridoxal 5'-phosphate synthase-like subunit PDX1.2
Sequence:
MGTHVAPWKQLLFGAIEANSHLSHSSYVQLATIGLNGRPSNRTVVFRGFEENSDRIQINTDLRSRKIEELKHCPFSEMCWYFSDTWEQFRINGRIEVIDASNPDQTKLQQREKAWFANSLRSRLIYVCPTPGSPCNSEQSSQQVKLDPSSGPVPEYCLLLLEPEKVDYLNLKTNQRLFFSSMATGTGEKCWTSEKVNP
Protein: Pleckstrin homology domain containing A7 (A0A8I6A7D6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MEPWRCLPRDARPAALGFWGEPLAACSHNQQTTTFRHPVTGQFSSENSEYVLREEPHPHMSKQERNQRPSSMVSETSTAGTTSTLEAKPGPKIIKSSSKVHSFGKRDQAIRRNLNVPVVVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISPVAPEDRISRKYSFKAVHTGMRALIYSTTTAGSQAEHSGMRTYYFSADTLEDMNAWVRAMNQAAQVLSRSSLKRDKVERQAMPQANHTDACQECGHVGPGHSRDCPRRGYEDAIVFDRREQEEERFRSQRDTLEGRRDRSKARSPYLPAEEDALFVDLPGGPRGQQAQPQRAERNGLPPYGLGEQNGTSGYSRTAPPRANLEKHSQRKTNLAQTEHWAKAQKGDGRSLPLDQTLPRQGPSQPPSFLENYQTLPRNTRYPSGSSSPPPRNLPSDYKYAQDRASHLKMSSEERRAHRDGTVWQLYEWQQRQQFRHGSPTAPIGAGSPEFTEQGRSRSLLEVPRSISVPPSPSDIPPPGPPRPFPPRRPHTPAERVTVKPPDQRRSVDISLGGSPRKARGHAVKNSSHVDRRSMPSMGYMTHTVSAPSLHGKSADDTYLQLKKDLEYLDLKMTGRDLLKDRSLKPMKIAESDTDVKLSIFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQTEQYRDQPQHLEKITCQQRLLQEDLVHIRAELCRESTEMENAWNEYLKLEKDVEQLKQTLQEQHRRAFFFQEKSQIQKDLWRIEDVMAGLSVNKENYRVLVGSVKNPERKTVPLFPHPSVPSLSPTESKPALQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVVSPLQSPTKATPQAEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDREQGQCVNGDLKVELRSYVSEPELASFSGDVPRPSLGLVGSESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAENSSVTFSRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGERTGLLSARYLSQPLPGDLGSWKREQEFDLQLLERAAQGDRKDKEEGWLKVQATPVMELDLEPQDYDLDINRELSKPEKVSIPERYVEVDPEEPPSVEELQARYQKAEKIRNILARSSMCNLQPPGQDRNSLADLDTQMQEQERIINISYALASEASQRSKQVAAQAVTDP
Protein: Interleukin-12 subunit alpha (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) (IL-12 subunit p35) (P54349)
Organism: Bos taurus (Bovine)
Function: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity). As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity). Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P29459}.
Interaction partners:
- Interleukin-12 subunit beta
- Interleukin-12 receptor subunit beta-1
- Interleukin-12 receptor subunit beta-2
- Leptin receptor
- Interleukin-6 receptor subunit beta
- Interleukin-27 receptor subunit alpha
- Interleukin-4 receptor subunit alpha
- Interleukin-6 receptor subunit alpha
- Ciliary neurotrophic factor receptor subunit alpha
- Interleukin 11 receptor subunit alpha
Sequence:
MCPLRSLLLISTLVLLHHLPHLSLGRSLPTTTASPGRSCLDYSQNLLRAVSNTLQKARQTLEFYSCTSEEIDHEDITKDKTSTVEACLPLELATNESCLASRETSFITNGHCLASGKTSFMTTLCLRSIYEDLKMYHVEFQAMNAKLLMDPKRQIFLDQNMLAAIAELMQALNFDSETVPQKPSLKELDFYKTKVKLCILLHAFRIRAVTIDRMMSYLSSS
Protein: Neuropeptide-like protein 1 (Q11088)
Organism: Caenorhabditis elegans
Function: In AWC olfactory sensory neurons, required for the detection of preferred food sources.
Interaction partners:
- Putative neuropeptide Y receptor 11
- FMRFamide-like neuropeptide 18
- FMRFamide-like neuropeptides 24
- FMRFamide-like neuropeptides 2
- G-protein coupled receptors family 1 profile domain-containing protein
- Neuropeptide-Like Protein
- FMRFamide-like neuropeptide 21
- Neuropeptide-Like Protein
- Neuropeptide-Like Protein
Sequence:
MKATFVLACLLVIAAVSHADLLPKRMDANAFRMSFGKRSVSNPAEAKRMDPNAFRMSFGKRSAEQNEQANKEDKATSDKLYDDTKFEEMKRMDANAFRMSFGKRSDAHQAADDQVEYVNDDFSLPEQKRMDANAFRMSFGKRVNLDPNSFRMSFGKRSTVGYNLDARNYFVGLGRR
Protein: Vitamin H transporter (H(+)/biotin symporter) (P53241)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in uptake of biotin with the concomitant entry of protons.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- 7-keto 8-aminopelargonic acid transporter
- Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
- Biotin synthase, mitochondrial
- Dethiobiotin synthetase
- Transcription factor VHR1
Sequence:
MTISNKSWRSYFPHLRKLPEDDQYLYSDDTNSSIIAEEELHHSVDKSSKTDVTAETTAVEPHPHNLRHDLPYEVRDEAGRKWWKYFDEFEYRVNKEYKKSRKWYEFLYPNHTTQTKAERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAYSGSYTLWLKSNTKYSIAQVNNLSVIPACLGFAYVIFCAFGADLFRCKWIFMVFAAIMNTVSCALLIKWDIPSKAKWYAFFTTYFSVAASPCLWSFINDFLRFDPQVKAITWIAIYSFSQSTYAWIPTLAWPTVESPRFKTGYTVSLIFGAIYGLWTFVVLFFYKRNEKKHALGNGIILYDSNKGEELPEFVKKNMEERDGYYYLKRSS
Protein: Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (C9JBX5)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115, ECO:0000256|RuleBase:RU368074}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115, ECO:0000256|RuleBase:RU368074}.
Interaction partners:
Sequence:
MRLLPRLLLLLLLVFPATVLFRGGPRGLLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLVEDKEEEDVSGEPEASPSADTTILFVKGEEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTVIEREDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE
Protein: Mnt, isoform F (E1JJE8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSGIGGIGVLLEAAQFLEQHEKLPQAGGGGGSALGVGVALPQQQQQTVHCKSNSIINNNNSSQHNRNSSSSSNGIIATPPFTNGNGNGTVGVGNASAIFNVSVNANGNGLSNGHSSPRSQLAAAATAHDYEYSAAGVANGHSEGRPHVSEDDNSSINNNNNNNNTHPPQQQQHSAAGRTTTTRITTTPAILTKLMGNSVTPASNTTSLPTSTPSVTTSPPASTDFMLLAAAATSATSATPATATSAAATAASNPAKRKLSSIAEIPSKFLVVSDAKGVYSAHTHPNGFAADSLGVDNNETMIKKLMQNLQSQRQQQSLQQLRSLRPAEISLTPPPAATRKVDISNSRTRSYSLSNVSAARDQQDHPQHQQHANHMQIQQHYGYMRSNIGGVIYGLHKDSADSAASSACGAGAGAAAVGMSIASSAPAAGSQLSAHHHTGHGGRRRTTSSNSNGAGTREVHNKLEKERRAQLKECYDLLKKVLPMGDEDRKKTSNLTILDTAHKYVNSLSHEVCEQEAKIEKLAKQKIELQKRLKQLSLRRESPPTDQQIIPQADKVCLATTATTAPPTAASGHNGTTILFDAGNACATGQLTTVINKTNGGATAAASSKHNGNHTGGATTTLTPAMGIMTIKNGNGSNGNMLAISPTGGHNHQLHQHHNGSPAGSPSGIGATTGATITRGSPTPSTPSPSPSSSSSGVSLSTSFMGGSSSSSSSSSSSSSSSSSSSSSSPTQQQQIITPTATARSVGLKFHGGAGAAVPAGGGSVNGFHQADKDRNYTFLRLSAGTTAQ
Protein: Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) (Q8WWZ8)
Organism: Homo sapiens (Human)
Function: May be involved in hepatocellular function and development.
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:12939600}. Note=Can be secreted into blood.
Interaction partners:
Sequence:
MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNGTHVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPIRIDWED
Protein: GEO02541p1 (Q2PDQ7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPNVIVNLSLIFLFLGGIFHLNEAQTTDCSNSCIFRARCTPYYKDLVWSVVDRVCRVFQNGCIFANENCMRANRCLPPMVATTKEECTKEIYCPRWCSRGAPPVCAWFPYTDSNGNTGGRDMSFGSRCLLDMYACRNEQAYVNEPRIGSCT
Protein: NADH-ubiquinone oxidoreductase chain 6 (EC 7.1.1.2) (Q2F943)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Mitochondrion membrane {ECO:0000256|RuleBase:RU004430}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU004430}.
Interaction partners:
Sequence:
MILSVLSSPALVSGLMVVRAKNPVHSVLFPILVFCDTAGLLILLGLDFSAMISPVVHIGAIAVSFLFVVMMFNIQIAEIHEEVLRYLPVSGIIGLIFWWEMFFILDNETIPLLPTHRNTTSLRYTVYAGKVRSWTNLETLGNLLYTYYSVWFLVSSLILLVAMIGAIVLTMHRTTKVQRQDVFRRNALDSRRTIMRRTTDQITIY
Protein: Annexin D8 (AnnAt8) (Q94CK4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At2g21655)
- Inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- At4g07515)
- Defensin-like protein 44
- Protein DOWN-REGULATED IN DIF1 11
- Protein PATRONUS 2
- Exocyst complex component SEC10b
- ECA1 gametogenesis family protein
- Defensin-like protein 181
- Disease resistance protein RPP2B
Sequence:
MATIVSPPHFSPVEDAENIKAACQGWGTNENAIISILGHRNLFQRKLIRQAYQEIYHEDLIHQLKSELSGNFERAICLWVLDPPERDALLANLALQKPIPDYKVLVEIACMRSPEDMLAARRAYRCLYKHSLEEDLASRTIGDIRRLLVAMVSAYKYDGEEIDEMLAQSEAAILHDEILGKAVDHEETIRVLSTRSSMQLSAIFNRYKDIYGTSITKDLLNHPTNEYLSALRAAIRCIKNPTRYYAKVLRNSINTVGTDEDALNRVIVTRAEKDLTNITGLYFKRNNVSLDQAIAKETSGDYKAFLLALLGHGKQL
Protein: Cyclic-di-GMP-binding biofilm dispersal mediator protein (P39333)
Organism: Escherichia coli (strain K12)
Function: Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP, which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility, cell size, cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase.
Interaction partners:
- HTH-type transcriptional repressor BdcR
- RutC family protein YjgH
- NADH-quinone oxidoreductase subunit C/D
Sequence:
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
Protein: Exocyst complex component 5 (Exocyst complex component Sec10) (A0A8C0Q1Y6)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Interaction partners:
Sequence:
MATTAELFEEPFVADEYIERLVWRTPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAAILCQRVNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKDQLEECRKSDAEQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSRSAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQRTNLPLGPSIDTHGETFLSQEVVVNLLQETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSRNANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECLQKKKEIIEQMEMKLDTGIDRTLNCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCAYVRKQVEKIKNSMDGKNVDTVLMELGVRFHRLIYEHLQQYSYSCMGGMLAICDVAEYRKCAKDFKIPLVLQLFDTLHALCNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHFS
Protein: Protein CMS1 (Complementation of MCM10 suppressor protein 1) (Q07897)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May play a role in the regulation of DNA replication and cell cycle control.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- ATP-dependent RNA helicase ROK1
- Ribosome biogenesis protein UTP30
- Essential nuclear protein 1
- Ribosome biogenesis protein ENP2
- Ribosome biogenesis protein BMS1
- rRNA processing protein RCL1
- Multiple RNA-binding domain-containing protein 1
- Protein BFR2
- U3 small nucleolar RNA-associated protein 22
- Nucleolar protein 6
Sequence:
MSNPDDLDDGLAYDFDAEHEVIFDAKDGSPPTKKVQKRSIEQDDDDVDDIDGKKEERNSEDDSNRPISKRQKKLQKKSKLIEKKKEESQYIVSQRKALPASSPEKIIEYLTTLIREKNPDLSVLELEELYFKRNDFLSTEKFDAERRLSNFPAFIQKFSVAPKKIVFSMSNIRVADVYRSLNGGKNCVKLFSKSKLKDDIATVERLLTDSSKKSNKNKDSLYFIATPTRMQKIIEATDLLFQGKEKLDIILDASYLDPKDNTILSFENAAVLCQVLKTFLNKKSSVKILLY
Protein: Ribonuclease UK114 (EC 3.1.-.-) (Perchloric acid-soluble protein) (PSP) (P83145)
Organism: Gallus gallus (Chicken)
Function: Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11163312}.
Interaction partners:
Sequence:
TTVFLADIKSNCPSRVSFQVAALPGARVEIEAIAIQGPI
Protein: Protein EXECUTER 2, chloroplastic (AtEX2) (Q94AT5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Together with EX1, enables higher plants to perceive singlet oxygen as a stress signal in plastid that activates a genetically determined nuclear stress response program which triggers a programmed cell death (PCD). This transfer of singlet oxygen-induced stress-related signals from the plastid to the nucleus that triggers genetically controlled PCD pathway is unique to photosynthetic eukaryotes and operates under mild stress conditions, impeding photosystem II (PSII) without causing photooxidative damage of the plant.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:17540731}.
Interaction partners:
- At5g61660
- Pentatricopeptide repeat-containing protein GUN1, chloroplastic
- 3'
- Serine/threonine-protein kinase STN7, chloroplastic
Sequence:
MATTQPCLIGQIIAVPQFHILFSPRNSLKPELSTNKRTNFSVSIGLRHSFASSISTCNPKAPSLSCLRNCAAVDGADTSSSEDKWDWDWDRWNRHFSEIEEVESVVSLLKSQLEDAVEKEDFEEAVKLKQAISEATVDDAVAEIMRQLQTAVNEERYHDASRLCNETGSGLVGWWVGLPRDSEEPFGRIVHITPGVGRFIGKSYSPRQLVAEAAGTPLFEIFVIKDTDGGYVMQVVYVQHVKQNLTISENSFSKVQQSSKSSINDPSILDVRGSELKVDKKEDTQLNAGEPTEEGIKNVIKFLKDKIPGLKLKVMDVIKIPEEEIVGSDDATEELVGEGTEETNSSDDEEEVEEEENDSIEAISSMDSADYGKHSNTKLVIGGVLHNIEDSSIDDEIVRVSANIMDTERDSFILHVPGRSKRDIDTRKNRVSKEQVTALAAQGLSDLLPPEVAEAFWGEKASLKVSKHVHEIVKLAINQAQKGNHLSEYTAFNRIITPESNLDPFDGLYVGAFGPYGTEIVQLKRKYGRWDDAEGSNSSDIEFFEYVEAVKLTGDPNVPAGQVTFRARIGNGSRMTNHGLFPEELGVLASYRGQGKIADFGFKKPRWVEGKLLKLNGKGMGPYVKGADLGFLYIGPEQSFLVLFNRLRLPE
Protein: LD15904p (Putzig, isoform A) (Putzig, isoform B) (Q9VP57)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Chromator, isoform A
- Centrosome-associated zinc finger protein Cp190
- Nucleosome-remodeling factor subunit NURF301
- DNA replication-related element factor, isoform A
- TATA box-binding protein-like 1
- Chromosomal serine/threonine-protein kinase JIL-1
Sequence:
MNNQLNPATYRKFNNLLSSGAVTVTGPSQPRILKSTRMVVPGGGGGGGASAGGASAVGGVAQQQAVNDAESGGVGIGGLATRCYICDDRCEPQTSLTDMCTTHTSTKFPNKLAQLVGEGFLVIVCGEDYVCSRCTNLVNYYDRLENDVERVKTNLISLLNKKYAINEDMGQEGSPPLKMQKMVGGSANRSLEESPSADLLRPRKLLQGNPVGQSKIAPGTTQSSVQGTQTVQRKATKIYKCTSCDYKTSDMRLFNTHYETCKQQTFQCKTCRKIFPHFGAMKQHMVRDHNTAMDNTCAMCHINFVNENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAAAAAAAAANENLVGTSLYTCNHCQFKSTDKVVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQTNFFKCGTCSMTFPKREMLVKHFEVHQSPSASTVSPKQSVSQNLNTQKLLQETIDEALSDSLPASTAAVVATTESENNIRFFSCSICSLTFIQETYYNHHMETHRRDKKATSAGATALNSAATALLSDEPGEATGKAGDESGEQNAEADIESLFEKLHSDKNESGEAPKPGSKGGEMVITSQEGSGGITFNITIPQPDGDQSQKDSPNTTAPVSVSIDMPNLDQAEDESQSQGSIDAKGESGEASSADSKSNAAPVSMPSLDDDNEAAAAEAEASEETKTASKAGQEKAKAKAGESAKSKEAAAAEEPQPSDEGDVVAKREATDTPTTESEANATTAEAGESGEGEVTASTGAEGEAGEAAGGEHVAMELDEAMQAQVEGGQIKFIVNENGHLLQLDNHILTDAEGNQIIVQDPEQIQQLLQSVGVLQSGEGLEGETLQMMTDGSGQMVLVHGDNNEQQLIDASLLNSEGQLIIQQGQDGEEGAHVISEDGTRIPVSVSYTEDGQPIVQVQQQVLEAAQQAASASGGADDKEAAADSAGEEVQVSEASSGTASTTVVATSTASSTGGPSGGSFFALEEFTETKTD