wanglab/gogpt-training-data huggingface dataset:
Protein: Plant intracellular Ras-group-related LRR protein 1 (Q9FFJ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction. PIRL1 acts redundantly with PIRL9 in the differentiation of microspores into pollen.
Interaction partners:
- S-protein homolog 11
- S-protein homolog 10
- F-box protein At3g17710
- Immune-associated nucleotide-binding protein 4
- Pectinesterase QRT1
- Calmodulin-like protein 2
- At2g19340
- Probable receptor-like protein kinase At2g23200
- Zinc finger CCCH domain-containing protein 26
- Inactive RHOMBOID-like protein 8
Sequence:
MATELNPKNFPVLSYVLDRLPSFTAKSSSSSDVEPPPSKSDPSSSSNHSIEIVTQMPHLAHPDVLASMTNATADVSQTRSVLRTLGPRPDHETVDRARARLREIDASLSESFEEIALSPNDIDVAEKEQKRREAVEQEKIWYKSILKLNELHESYEKLLKEAEERLVRIYESAEKNAAAVAEEEAAEVEVNEEVVSILQQAAENPLDRVDLSGRKLKLLPEAFGKIQGLLVLNLYNNQLQAIPDSIAGLHNLLELDVSTNFLETLPDSIGLLSKLKILNVSCNKLTTLPDSICHCGSLVVLDASYNNLTYLPTNIGFELVKLEKLLIHLNKIRSLPTSIGEMRSLRYLDAHFNELNGLPNSFGLLTNLEYLNLSSNFSDLQDLPASFGDLISLQELDLSNNQIHSLPDAFGTLVNLTKLNLDQNPLVVPPDEVVKQGVDAVKMYMGKRWVSMLEEEEKMANMKDEMDQTNTDWLTRTTSKLKTYVTEVSEYLGSNPPRDPYLDQQL
Protein: Thioredoxin reductase (TR) (TRXR) (EC 1.8.1.9) (P9WHH1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Essential thiol-reducing enzyme that protects the cell from thiol-specific oxidizing stress. Plays a minor role in defense against oxidative and nitrosative stress. Is essential to establish and maintain infection in mice.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Thioredoxin
- Thioredoxin
- Alkyl hydroperoxide reductase C
- Probable thioredoxin TrxA
- Probable cysteine desulfurase
- Uncharacterized protein Rv1324
- Probable thioredoxin ThiX
- Anti-sigma factor RshA
- Anti-sigma-M factor RsmA
- ECF RNA polymerase sigma factor SigH
Sequence:
MTAPPVHDRAHHPVRDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMDEMREQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRDQDIAVIGGGDSAMEEATFLTRFARSVTLVHRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVREAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAATGEADSTDALIGAQR
Protein: Bombinin-like peptides [Cleaved into: Bombinin-BO1; Bombinin H-BO1] (A0A219CMY0)
Organism: Bombina orientalis (Oriental fire-bellied toad)
Function: Has antimicrobial activity against Gram-negative bacterium E.coli (MIC=26.3 uM), Gram-positive bacterium S.aureus (MIC=26.3 uM) and yeast C.albicans (MIC=52.5 uM). Has moderate hemolytic activity towards human erythrocytes at a concentration of 52.2 uM.
Subcellular location: Secreted {ECO:0000255, ECO:0000269|PubMed:29098406}.
Interaction partners:
Sequence:
MNFKYIIAVSFLIASAYARSEEYDIQSLSQRDVLEEESLRKIRGIGSAILSAGKSIIKGLAKGLAEHFGKRTAEDHEVMKRLEAAMRDLDSLDYPEEASERETRGFNQEEKEKRIIGPVLGLVGKALGGLLG
Protein: Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6) (P17066)
Organism: Homo sapiens (Human)
Function: Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.
Interaction partners:
- DnaJ homolog subfamily B member 1
- Heat shock 70 kDa protein 1A
- DnaJ homolog subfamily B member 4
- Toll-like receptor 2
- Heat shock 70 kDa protein 4
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- DnaJ homolog subfamily A member 1
- DnaJ homolog subfamily B member 6
- Heat shock protein HSP 90-beta
Sequence:
MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD
Protein: Co-chaperone (A0A1D8PIG5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Flavin reductase like domain-containing protein
- Uncharacterized protein
- Heat shock protein 90 homolog
- Hsp90 co-chaperone Cdc37
- Hsp90 cochaperone
- E3 ubiquitin ligase complex SCF subunit
- Adenylate cyclase
- Aha1p
- Fgr32p
- hydroxyacylglutathione hydrolase
Sequence:
MAIEQFITKGDDALKSKDYLGAISYYSQAIKENPQAFSPYLKRSTAYQKLKNNDKAKADISSAFSIATEKGKRVDIGLCYFKLGLVYYQEKKVKLSLTQFEKAVEYDCKEPTLSMWKAKAEYDLKNHPEWNVEGDKEEDDDIDLVLGVENEYTQSMANTEKDKSHEPKIVELDANEESSEKKSNQESTSSAPAAQATTQAPKSTNVDVINKIAPLNVKFRDDWYQSNEEVIITIYAKKVNEEKLKVEFDTNSVCISFPSAAASEYKYYLDPLFAEIVPSESKYKVYSTKLEITLKKKDANKWPELEKQAVEGVTDNQDKDKKVDPSELVYPTSSKKKINWNNFKIDDDDKEEGNENDFFRKIFKDVDEDSRRAMMKSYVQSNGTVLTTSWDEAKDKEFEVLPPDGMEVKKWDT
Protein: PR5-like receptor kinase (EC 2.7.11.1) (Q9FF29)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses kinase activity in vitro.
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Histone H3 K4-specific methyltransferase SET7/9 family protein
- Histone H3 K4-specific methyltransferase SET7/9 family protein
- Uncharacterized protein
- Leucine-rich repeat
- At2g35170/T4C15.16
- AT4g17080/dl4570w
- At3g05070
Sequence:
MVEGFSLSLMFLLVSHFFVSGVMSRNFTIENKCDYTVWPGFLTMTTAVSLPTNGFSLKKGESRVINVPPSWSGRLWGRSFCSTSSTGNFSCATGDCGSGKIECSDSGARPPTTLIDFTLDATDGQDFYDVSVVDGYNLPLVVVPQRLGSGRTCSNVGCVVNLNKTCPSELKVMGSSNKEHPIACMNACQKFGLPEFCCYGEYGKPAKCQPTLYSTNFKNECPLAYSYAYDNENNTFRCSNSPNYVITFCPNDISSMSQPSKETNGGTKQKSSWKLKLIVGVSAALTLMILIVVVIIVRTKNMRNSEWNDQNVEAVAMLKRYSYTRVKKMTNSFAHVLGKGGFGTVYKGKLADSGRDVAVKILKVSEGNGEEFINEVASMSRTSHVNIVSLLGFCYEKNKRAIIYEFMPNGSLDKYISANMSTKMEWERLYDVAVGISRGLEYLHNRCVTRIVHFDIKPQNILMDENLCPKISDFGLAKLCKNKESIISMLHMRGTFGYIAPEMFSKNFGAVSHKSDVYSYGMVVLEMIGAKNIEKVEYSGSNNGSMYFPEWVYKDFEKGEITRIFGDSITDEEEKIAKKLVLVALWCIQMNPSDRPPMIKVIEMLEGNLEALQVPPNPLLFSPEETVPDTLEDSDDTSTFFNPSHFERGTLLDSEDVLQHGSRSS
Protein: NADH-ubiquinone oxidoreductase 51 kDa subunit homolog SPBC18E5.10, mitochondrial (EC 1.6.-.-) (O94500)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Cytochrome c1, heme protein, mitochondrial
- NADH-ubiquinone oxidoreductase 24 kDa subunit homolog C11E3.12, mitochondrial
- Putative acyl carrier protein, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- RNA polymerase I-specific transcription initiation factor rrn11
- Probable mitochondrial-processing peptidase subunit beta
- Cytochrome b-c1 complex subunit 7
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Uncharacterized mitochondrial carrier C12D12.05c
- Cytochrome b-c1 complex subunit 9
Sequence:
MLSRGHCCKLKHSFNGLRNVALKRLVGSKAGYRMFPNLIEKRIRRIDDALADGEYENLSEILKYDPLNIIELVQESELRGRGRYGFPTGEKMLSLYKATSSERGRKEKPVVIVNAAENDIGSFKDRLLLRHEPHKIIEGAIIAARAVEASACYLFIRKDYYEETVMMQKCIIQAYAKKLLGKNLLGTSIGLELLIHPGAGSYITGEESALIQSLQGEFPVPDIPINNTITSGLFGLPTLVLNVETVSNLPAIIKKGPKFFISMGRPNNRGTKLFSISGEVNEPNVIEACMSIPLKDLIENYAGGVRGGWNKLVGIFPGGPCSGILNKNQCEQVTMDFDSLKALDSSLGTGSVIVLNDHDQIFESLLNFAKFYSTNTCHTCPVCRDGVEDVIETLKGLKDGHAHLSQLKDMFSKFNMPSSSKVFCGFGDSMRHQIHSIQRNFPDQITFRTKVT
Protein: WRKY transcription factor 23 (WRKY DNA-binding protein 23) (O22900)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MEFTDFSKTSFYYPSSQSVWDFGDLAAAERHSLGFMELLSSQQHQDFATVSPHSFLLQTSQPQTQTQPSAKLSSSIIQAPPSEQLVTSKVESLCSDHLLINPPATPNSSSISSASSEALNEEKPKTEDNEEEGGEDQQEKSHTKKQLKAKKNNQKRQREARVAFMTKSEVDHLEDGYRWRKYGQKAVKNSPFPRSYYRCTTASCNVKKRVERSFRDPSTVVTTYEGQHTHISPLTSRPISTGGFFGSSGAASSLGNGCFGFPIDGSTLISPQFQQLVQYHHQQQQQELMSCFGGVNEYLNSHANEYGDDNRVKKSRVLVKDNGLLQDVVPSHMLKEE
Protein: Mitochondrial pyruvate carrier (A0A087WVZ0)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
Interaction partners:
Sequence:
MAGALVRKAADYVRSKDFRDYLMRTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIKHEMTKTASA
Protein: 2'-5'-oligoadenylate synthase 1 ((2-5')oligo(A) synthase 1) (2-5A synthase 1) (EC 2.7.7.84) (p42 OAS) (Q29599)
Organism: Sus scrofa (Pig)
Function: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P00973}. Mitochondrion {ECO:0000250|UniProtKB:P00973}. Nucleus {ECO:0000250|UniProtKB:P00973}. Microsome {ECO:0000250|UniProtKB:P00973}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P00973}. Secreted {ECO:0000269|PubMed:20844035}. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions. {ECO:0000250|UniProtKB:P00973}.
Interaction partners:
Sequence:
MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI
Protein: Neutral amino acid transporter A (Alanine/serine/cysteine/threonine transporter 1) (ASCT-1) (Solute carrier family 1 member 4) (O35874)
Organism: Mus musculus (Mouse)
Function: Sodium-dependent neutral amino-acid transporter that mediates transport of alanine, serine, cysteine, proline, hydroxyproline and threonine.
Subcellular location: Membrane {ECO:0000250|UniProtKB:P43007}; Multi-pass membrane protein {ECO:0000255}. Melanosome {ECO:0000250|UniProtKB:P43007}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:P43007}.
Interaction partners:
- Amino acid transporter heavy chain SLC3A2
- High affinity cationic amino acid transporter 1
Sequence:
MEKSGETNGYLDGTQAEPAAGPRTPETAMGKSQRCASFFRRHALVLLTVSGVLVGAGMGAALRGLQLTRTQITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASLDASSLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGAGAQTLQSSSLGLENSGPPPVSKETVDSFLDLLRNLFPSNLVVAAFTTSATDYTVVTHNTSSGNVTKEKIPVVTDVEGMNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVEMKDIVMLVTSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILAVDWIVDRTTTVVNVEGDALGAGILNHLNQKVVKKGEQELQEVKVEAIPNSKSEEETSPLVTHQNPAGPVAIAPELESKESVL
Protein: Putative methyltransferase DDB_G0268948 (EC 2.1.1.-) (Q55EX9)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MTSPIPTPTKFDDKFGSISKSYKNFRPTYNDELYSIIDSHCDEKRDLAIDIGAGSGQATVRLAKYFKKVIGFEPSQGQIENAEKTDNVEYRLSAAEKIDLPSGSVDLITVAQAAHWFNLPVFYEESKRLLRENGSLIIWSYGLMKITNNNDAQVVHEKHYYETIGDQYWAPERKYIDDEYVDIKPSFENTTRKTISLPKSMSINDMIGYYSSWSGYAAFIKAGNKDVLPEIKETLLKAYKTTDGDSKLIDVNFPVYMILSKKE
Protein: Ribosomal RNA small subunit methyltransferase F (EC 2.1.1.178) (16S rRNA m5C1407 methyltransferase) (rRNA (cytosine-C(5)-)-methyltransferase RsmF) (P76273)
Organism: Escherichia coli (strain K12)
Function: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Ribosomal RNA large subunit methyltransferase I
- Ribosomal RNA small subunit methyltransferase E
- Ribosomal RNA small subunit methyltransferase I
- Ribosomal RNA large subunit methyltransferase E
- Lipophilic envelope-spanning tunnel protein B
- Lipophilic envelope-spanning tunnel protein A
- Ribosomal RNA small subunit methyltransferase H
- tRNA sulfurtransferase
- 23S rRNA
- 23S rRNA
Sequence:
MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQISARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKDREAGQIRQAATGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNMNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTGNA
Protein: Uncharacterized protein (A0A060WRB3)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MAMLTISLLLCAAVALTGATVLELFQDFEQALLLGAKGEEGVVAAENRNQCPTGWFQFGSRCFMFVETARSWPLAERHCVSLGANLASVHSSAEYQFLQEVVASKTGGFSTPWIGGFDAVQDRLWFWSDGSEFDYQNWKKGEPNNSGGREPCIVINWGDEYRWNDINCGNSFPSVCSKRMCEIQKN
Protein: ATPase family gene 2 protein homolog A (EC 3.6.4.10) (AFG2 AAA ATPase homolog A) (Ribosome biogenesis protein SPATA5) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5) (Q8NB90)
Organism: Homo sapiens (Human)
Function: ATP-dependent chaperone, which plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles. Acts together with SPATA5L1, C1orf109 and CINP. May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18445686}. Mitochondrion {ECO:0000250|UniProtKB:Q3UMC0}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18445686}.
Interaction partners:
- AFG1-like ATPase
- Ubiquitin conjugation factor E4 B
- ATPase family gene 2 protein homolog B
- Cyclin-dependent kinase 2-interacting protein
- Ubiquitin recognition factor in ER-associated degradation protein 1
- Ubiquitin conjugation factor E4 A
- Phospholipase A-2-activating protein
- Derlin-1
- UBX domain-containing protein 7
- Proteasome subunit beta type-2
Sequence:
MSSKKNRKRLNQSAENGSSLPSAASSCAEARAPSAGSDFAATSGTLTVTNLLEKVDDKIPKTFQNSLIHLGLNTMKSANICIGRPVLLTSLNGKQEVYTAWPMAGFPGGKVGLSEMAQKNVGVRPGDAIQVQPLVGAVLQAEEMDVALSDKDMEINEEELTGCILRKLDGKIVLPGNFLYCTFYGRPYKLQVLRVKGADGMILGGPQSDSDTDAQRMAFEQSSMETSSLELSLQLSQLDLEDTQIPTSRSTPYKPIDDRITNKASDVLLDVTQSPGDGSGLMLEEVTGLKCNFESAREGNEQLTEEERLLKFSIGAKCNTDTFYFISSTTRVNFTEIDKNSKEQDNQFKVTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNEVEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQDRLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRILKKQPNLPDVKVAGLVKITLKDFLQAMNDIRPSAMREIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVERGSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLALEEDIQANLIMKRHFTQALSTVTPRIPESLRRFYEDYQEKSGLHTL
Protein: Heat shock protein 26 (26 kDa heat shock protein) (P15992)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known. One of the major polypeptides produced on heat shock.
Interaction partners:
- Heat shock protein 104
- Heat shock protein 42
- Heat shock protein 78
- Heat shock protein SSA4
- 12 kDa heat shock protein
- Heat shock protein homolog SSE2
- Heat shock protein SSA1
- ATP-dependent molecular chaperone HSP82
- Heat shock protein SSA3
- Mitochondrial protein import protein MAS5
Sequence:
MSFNSPFFDFFDNINNEVDAFNRLLGEGGLRGYAPRRQLANTPAKDSTGKEVARPNNYAGALYDPRDETLDDWFDNDLSLFPSGFGFPRSVAVPVDILDHDNNYELKVVVPGVKSKKDIDIEYHQNKNQILVSGEIPSTLNEESKDKVKVKESSSGKFKRVITLPDYPGVDADNIKADYANGVLTLTVPKLKPQKDGKNHVKKIEVSSQESWGN
Protein: RNA-binding motif protein, Y chromosome (RNA-binding motif protein 1) (RNA-binding motif protein, Y chromosome, family 1 member A1) (Y chromosome RNA recognition motif 1) (O35698)
Organism: Mus musculus (Mouse)
Function: RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase 9Y
- Ubiquitin-like modifier-activating enzyme 1 Y
- Zinc finger Y-chromosomal protein 1
- ATP-dependent RNA helicase DDX3Y
Sequence:
MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI
Protein: Lipopolysaccharide export system permease protein LptF (Q9KP75)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004429}.
Interaction partners:
- Uncharacterized protein
- Lipopolysaccharide export system ATP-binding protein LptB
- Lipopolysaccharide export system protein LptC
- LPS-assembly protein LptD
Sequence:
MIIVRYLIRETIKSQFAIFFVLFLVFLSQKFIRVLADASDGEIPTSMILSIVGLNMPAMGLLMLPLSLYIGILLTFGRLYAESEITVMNATGIGNKFLIRAALYLALITASVAAFNALWLAPWSQDKEAHLMEQFAAENSVDLLQKGHFQRSPDGSSVVFIDNIENRKLYNVFVAQLAPRDSILPSVMFSHSGDVKELSDGRQIITLYDGTRYEGVPTRVDYMITNFDSYDGLIGQREVKSAERDWEALPTLSLLNNADRRAQAELQWRISLVVCIPLLTMLVVPLSAVNPRQGRFAKMGPAILIYLTYFLALSATKSAIEDGSLPVIIGLWPINAALLLAALMVNTLDSIPVRRFKDRWKQRKVA
Protein: RRM domain-containing protein (Q57WT3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Mago nashi-like protein,putative
- MIF4G domain-containing protein
- Nuclear cap-binding protein subunit 2
- Probable eukaryotic initiation factor 4A
- RNA helicase
- C3H1-type domain-containing protein
- RNA-binding protein, putative
- Regulator of nonsense transcripts 1, putative
- Pre-mRNA-splicing factor SLU7
- RNA-binding protein, putative
Sequence:
MITEGAATPCAEVPAIRRVRRTRSRFERLVRPEDVAPGEPTPSVEGWVLFLTNLPPNTTMDHITDLFVTREGEGLWNVREVKMPLDKNCECCGYALVELEKREAFEAALRDMEGMTLSFAEGEPPNGEDAWRLHIAPTFLGEKDDEEEELVAGGKRERE
Protein: Phosphoglycerate kinase (PGK) (EC 2.7.2.3) (P41759)
Organism: Schistosoma mansoni (Blood fluke)
Function: Involved in the seventh step in glycolysis. Catalyzes the conversion of 1,3-bisphosphoglycerate ((2R)-3-phospho-glyceroyl phosphate) to 3-phosphoglycerate ((2R)-3-phosphoglycerate) and results in the formation of ATP. Associated with the tegument to provide the energy needed for the tegumental repair resulting from immune damage.
Interaction partners:
- Triosephosphate isomerase
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Glucose-6-phosphate isomerase
- Pyruvate kinase
- Glyceraldehyde-3-phosphate dehydrogenase
- Enolase
- Putative cleavage stimulation factor
- phosphopyruvate hydratase
- 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Sequence:
MGLSKLSISDVDLKGKRVLIRVDFNVPMKDGKVTNTQRIAAAIPTIKYALDKGAKSVVLMSHLGRPDGHKVDKYSLKPVCPEVSKLLGKEVTFLNDCVGPDVVNACANPAPGSVFLLENLRFHVEEEGKGVSPTGEKTKATADQIKAFSESLTKLGDVYVNDAFGTAHRAHASMVGCQLPQKACGFLMNKELTYFAKALENPERPFLAILGGAKVSDKIQLINNMLDKVNELIIGGGMAYTFLKQIHNMHIGNSLFDAPGAEIVHKVMETAKAKNVAIHLPVDFVTADKFADDANTEIRTIQSGIADGWMGLDIGPKTIEEFSKVISRAKTIVWNGPMGVFEMDKFATGTKAAMDEVVKATKNGATTIIGGGDTATCCAKWDTEDKVSHVSTGGGASLELLEGKQLPGVVALTDAH
Protein: Smooth, isoform V (A0A0B4K7W7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPYNGASNGSGASGAGGGGATIVVTEGPQNKKIRTGVQQPGENDVHMHARSTPQQNQQQALMNKSNDDLRRKRPETTRPNHILLFTIINPFYPITVDVLHKICHPHGQVLRIVIFKKNGVQAMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNVYKNEPDTSWDYTLSTGEILPIATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPHPQHLHHQQQLVAPAQSHNLYQFKEPPLLGPGAAFPPFGAPEYHTTTPENWKGAAIHPTGLMKEPAGVVPGRNAPVAFTPQGQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVINPFLLPDHSPSFKEYTGSKNNRFLSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVPATSVRLFPLKTERSSSGLIEFSNISQAVLAIMKCNHLPIEGKGTKFPFIMKLCFSSSKSMNGAWNNAASEGMIEKENEVDTKVDIYN
Protein: Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1) (P28069)
Organism: Homo sapiens (Human)
Function: Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Specifically binds to the consensus sequence 5'-TAAAT-3'. Activates growth hormone and prolactin genes.
Subcellular location: Nucleus {ECO:0000269|PubMed:26612202}.
Interaction partners:
- Homeobox protein prophet of Pit-1
- Homeobox expressed in ES cells 1
- Prolactin
- LIM/homeobox protein Lhx4
- Thyrotropin subunit beta
- Growth hormone-releasing hormone receptor
- LIM/homeobox protein Lhx3
- Zinc finger homeobox protein 3
- Pituitary homeobox 1
- Homeobox protein ESX1
Sequence:
MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR