wanglab/gogpt-training-data huggingface dataset:
Protein: Cytoadherence linked asexual protein 3.2 (O77309)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- High molecular weight rhoptry protein 2
- High molecular weight rhoptry protein 3
Sequence:
MVSFFKTPIIIFFFLLCLNEKVLCSINENENLGENKNENANVNTPENLNKLLNEYDNIEQLKSMIGNDELHKNLTILEKLILESLEKDKLKYPLLKQGTEQLIDISKFNKKNITDADDETYIIPTVQSSFHDIVKYEHLIKEQSIEIYNSDISDKIKKKIFIVRTLKTIKLMLIPLNSYKQNNDLKSALEELNNVFTNKEAQKESSPIGDHGTFFRKLLTHVRTIKENEDIENKGETLILGDNKIDVMNSNDFFFTTNSNVKFMENLDDITNQYGLGLINHLGPHLIALGHFVVLKLALKNYKNYFEAKNIKFFSWQKILEFSMSDRFKVLDMMCNHESVYYSEKKRRKTYLKVDRSSTSMECNILEYLLHYFNKYQLEIIKTTQDTDFDLHGMMEHKYIKDYFFSFMCNDPKECIIYHTNQFKKEANEENTFPEQEEPNRQISAFNLYLNYYYFMKRYSSYGTKKTLYVHLLNLTGLLNHDTRAYVTSLYLPGYYNAVEMSFTDDKEFSTLFESLIQCIEKCHSDQARQISKDSNLLNNITKCDLCKGAFLYANMKFDEVPSMLQKFYVYLTKGLKIQKVSSLIKTLDIYQDYSNFLSHDINWYTFLFLFRLTSFKEIANKNVAEAMYLNIKDEDTFNKTIVTNYWYPSPIKKYYTLYVRKHIPNNLVDELEKLMKSGTLEKMKKSLTFLVHVNSFLQLDFFHQLNEPPLGLPRSYPLSLVLEHKFKEWMDSSPAGFYFSNYQNPYIRKDLHDKVLSQKFEPPKMNQWNKVLKSLIECAYDMYFEQRHVKNLYKYHNIYNINNKLMLMRDSIDLYKNNFDDVLFFADIFNMRKYMTATPVYKKVKDRVYHTLHSITGNSVNFYKYGIIYGFKVNKEILKEVVDELYSIYNFNTDIFTDTSFLQTVYLLFRRIEETYRTQRRDDKISVNNVFFMNVANNYSKLNKEEREIEIHNSMASRYYAKTMFAAFQMLFSTMLSNNVDNLDKAYGLSENIQVATSTSAFLTFAYVYNGSIMDSVTNSLLPPYAKKPITQLKYGKTFVFSNYFMLASKMYDMLNYKNLSLLCEYQAVASANFYSAKKVGQFLGRKFLPITTYFLVMRISWTHAFTTGQHLICAFDPKRCTPDCKNSTSYKSPQSFFYGWPPSSETYLFFYFFTNLYLDAYKSFPGGFGPAIKEQTQHVQEQTYERKPSVHSFNRNFFMELVNGFMYAFCFFAISQMYAYFENINFYITSNFRFLDRYYGVFNKYFINYAIIKLKEITSDLLIKYEREAYLSMKKYGYLGEVIAARLSPKDKIMNYVHETNEDIMSNLRRYDMENAFKNKMVTYVDDFAFFDDCGKNEQFLNERCDYCPVIEEVEETQLFTTTGDKNTNETTEIKKQTSTYIDTEKMNEADSADSDDEKDFDTPDNELMIARFH
Protein: At1g07750/F24B9_13 (F24B9.13 protein) (Putative globulin protein) (RmlC-like cupins superfamily protein) (Q9LQQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DNA repair protein XRCC3 homolog
- DNA repair protein RAD51 homolog 3
- Meiotic recombination protein DMC1 homolog
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A
- DNA repair protein XRCC2 homolog
Sequence:
MELDLTPKLPKKVYGGDGGSYSAWCPEELPMLKQGNIGAAKLALEKNGFAVPRYSDSSKVAYVLQGSGTAGIVLPEKEEKVIAIKQGDSIALPFGVVTWWFNNEDPELVILFLGETHKGHKAGQFTEFYLTGTNGIFTGFSTEFVGRAWDLDENTVKKLVGSQTGNGIVKLDAGFKMPQPKEENRAGFVLNCLEAPLDVDIKDGGRVVVLNTKNLPLVGEVGFGADLVRIDAHSMCSPGFSCDSALQVTYIVGGSGRVQVVGGDGKRVLETHIKAGSLFIVPRFFVVSKIADADGMSWFSIVTTPDPIFTHLAGNTSVWKSLSPEVLQAAFKVAPEVEKSFRSTRTSSAIFFPPSN
Protein: Peroxidase (EC 1.11.1.7) (Q9XGV6)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU362060}.
Interaction partners:
Sequence:
MASTIPIVTLLIVMLSCHAANAQLSPNFYASSCPNLQTIVRNAMSRAVNRETRIGASILRLFFHDCFVNGCDGSILLDDTATFTGEKNAVPNRNSARGFEVIDTIKTNVEAACSATVSCADILALAARDGVALLGGPTWQVPLGRRDARTASQSAANNQIPSPFANLATLTSSFAAKGLSTRDLTALSGGHTIGLARCTTFRGRIYNDTNIDANFAATRRANCPASGGDNNLAPLDIQTPTRFDNDYFRNLVARRGLLHSDQELFNGGSQDALVRTYSNNPATFSADFAAAMVKMGNISPLTGTQGEIRRNCRVVN
Protein: Ubiquitin-ribosomal protein eL40B fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40B (60S ribosomal protein L40) (CEP52)] (P0CH07)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
Subcellular location: [Ubiquitin]: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.; SUBCELLULAR LOCATION: [Large ribosomal subunit protein eL40B]: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- mRNA export factor elf1
- Elongation factor 3
- Polyubiquitin
- Ubiquitin-ribosomal protein eS31A fusion protein
- Ubiquitin-ribosomal protein eS31B fusion protein
- Ubiquitin-activating enzyme E1 1
- Ubiquitin-conjugating enzyme E2 15
- Ubiquitin-conjugating enzyme E2 4
- Large ribosomal subunit protein eL18A
- AMSH-like protease sst2
Sequence:
MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCEKQICRKCYARLPPRATNCRKKKCGHTNQLRPKKKLK
Protein: CRP-like cAMP-activated global transcriptional regulator (cAMP receptor protein) (CRP) (cAMP regulatory protein) (Q79VI7)
Organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Function: Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism. May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes. It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source, however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate, it is conceivable that it is unable to function as an activator under acetate conditions.
Interaction partners:
- Adenylate cyclase, family 3
- HTH-type transcriptional activator RamA
- HTH-type transcriptional regulator RamB
- Diguanylate cyclase/phosphodiesterase domain 2
- Metal-dependent hydrolases of the beta-lactamase superfamily III
Sequence:
MEGVQEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVADHPAIAEQLLRVLARRLRRTNASLADLIFTDVPGRVAKTLLQLANRFGTQEAGALRVNHDLTQEEIAQLVGASRETVNKALATFAHRGWIRLEGKSVLIVDTEHLARRAR
Protein: Geminin coiled-coil domain-containing (E7FDS4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Multicilin
- Protein mab-21-like 3
- Cilium assembly protein DZIP1L
- Forkhead box protein J1-A
- Phosphatase, orphan 2
Sequence:
MLSCQDLSFAGGQRYEYCASTSADGSVDVSTTTLVSLWDAGPLDNAARQHEPPRRDSLLESGLGHQPTWHDQLSPQLQRNKQLQDTLMQREEELARLQEENNKLKEFLNSSYVKSLEEKSKKLLFNGKVPDVSRHRKRMHGDFRNLSQLLHTSEGKRTCRNLSLEFCSAEELAATPPLDSWVLETLGLQDENTINPERSLNTTTFSRPLPTEDRYSVDNTTGFSPNAGTHCDYSSIVDSSSNCSLDTSSGYSTSQSLGSDYSTLDPSALYTITSTGSPVSSPPALTTAQHFTPPRAASTPYRPQDVSPYYSTPGCGSSTSPGGDKQLFSTPRMSRSKTDLAFSMSLSPQNSVKTHSFPQGQAFTRRDAQGGWNFTWVPKQCS
Protein: Small polypeptide DEVIL 3 (Small polypeptide ROTUNDIFOLIA LIKE 21) (Small polypeptide ROT-FOUR-LIKE 21) (Q6X5U0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, including leaves shape, pedicule elongation, inflorescence organization and fruit maturation, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Small polypeptide DEVIL 15
- Small polypeptide DEVIL 19
- AT4g05070 protein
- Transmembrane protein
- Secreted transmembrane peptide 5
- Succinate dehydrogenase assembly factor 4
- Small polypeptide DEVIL 10
- Protein RALF-like 24
- At3g13845
- At1g67860/T23K23_29
Sequence:
MKGTKKKTPCNKKLGGYLKEQKGRLYIIRRCVVMLICWHD
Protein: Transcription factor Spi-C (Q8N5J4)
Organism: Homo sapiens (Human)
Function: Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein NipSnap homolog 3A
- Protein NipSnap homolog 3B
Sequence:
MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTEEPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
Protein: Transcription initiation factor TFIID subunit 2 (TBP-associated factor 2) (P87121)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by taf1), facilitation of DNA opening and initiation of transcription (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}. Note=Localizes at the barrier septum.
Interaction partners:
- SAGA complex/transcription factor TFIID complex subunit Taf12
- Transcription initiation factor TFIID subunit 13
- SAGA complex/transcription factor TFIID complex subunit Taf9
- SAGA complex/transcription factor TFIID complex subunit Taf6
- TATA-box-binding protein
- Transcription initiation factor TFIID subunit 11
- SAGA complex/transcription factor TFIID complex subunit Taf10
- Transcription initiation factor TFIID subunit 8
- Transcription initiation factor TFIID subunit 7
- Putative transcription initiation factor TFIID 111 kDa subunit
Sequence:
MSQLVDVPARGHQKVAIDIDFASQTIIGRTDITVNPIDSNLQKIVLDCYQAEIHSVYVNGDLTKFSYSDALKKLRIDEPNSTVNQHHQLNLQYEALMNDLGGINIFLSKPPGDELRPLIVSIDFSVHQPIFGITFVGIDPVDHRYPHVFTNNSIIPYSTCSWLPCVDGIWERSTWEFEITLPKTLSSLMHREKTQPSDLNNGANGVDGHDDNYENNRFDHQFNLSNEPDLLEDHDIEVICCGDLLDQVTHPKDMRKKTVYFSVTTPVAPNYIAFAAGPFKHINLTDFREPEDDDAMGSSAIDITGYYLPKYAEEVENTCVFLYKAMDFFVREYGSYPFNSFKLCFVDETNFPIISTPSLVISSNSILYPKDSLDQIYDSTKTLTWALASQWIGVYLIPKAWSDLWLIYGLSYYICGLFLKKLMGNNDYRFRLKKQVYRLLELDIGKPPISQRNINIPIDPNTLDFIALKSPLVIHILERRLTKTGGSLGMSRVIPKLLLQVMSGDMLNGCLSTSHFLKTCEKASHMRLDVFAQQWIYGYGYPIFRVVQRFNRKKMIIEMGIDQVQTKEAPRAPMSDKNFLSDAIRHLNNESIPTGLPVFSGPMTIRIHEADGTPYEHVVELKDSFTKLDIQYNTKYKRISRNRSTKNVKRDGDHNGDDSDYVIRSLGDVLQSDEDIERWHLYDYTKEEEDTMATEAFEWIRVDADFEWICDLRVRQPEHMYVSQLQQDRDVVAQLETIRHFTSESFTVSQQVSTVLLRTLLDNRYYYGIRQEAARALARCAIPELDWVGYYHLRMAYLEKFCFKDSTIPKSNDFSNITEYYVKCAMLESFPNIRDRKGVTPSSVKKLLLDLLCYNDNANNEFSDAYFICLLIDSLVEGLIPRGETVQYAFSDPEHMEFVNQVINEIDRYMRIDACMPSFKNIITCKSLKAKLRLAQTFHLEFGPKELLPYTQEGNYVLVRCIAFNLMLQAGALKYTPLIKYIFYILTNDLSPVVRRSLLYSVQDGLGALARGGTKSDVASEDLIVEEDITKAVEKRIDITSRASISGAIEALRNDLGQNHDFATEIWNAINNPKSDLLTKRNLLMICRVLYKAKSSLLVTLKIPSLIPRLRAIHLGKGKIVIKKAPLKQITSKTKEKSTSPTPPSITINPIKPKGPTLKIKLTNLRSTPPSH
Protein: Large ribosomal subunit protein uL16 (60S ribosomal protein L10) (Protein QM homolog) (Ribosomal protein L10) (Q6ZWV3)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:36517592}.
Interaction partners:
- Large ribosomal subunit protein eL21
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL13
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein uL18
Sequence:
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS
Protein: DNA-directed RNA polymerase subunit Rpo12 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit P) (B8YB64)
Organism: Saccharolobus shibatae (strain ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12) (Sulfolobus shibatae)
Function: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00615, ECO:0000269|PubMed:22848102}.
Interaction partners:
Sequence:
MAVYRCGKCWKTFTDEQLKVLPGVRCPYCGYKIIFMVRKPTIKIVKAI
Protein: Magnesium transporter MRS2-6, mitochondrial (Magnesium Transporter 5) (AtMGT5) (Q1PE39)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Magnesium transporter that mediates the influx/efflux of magnesium in a concentration-dependent manner. Plays a crucial role in male gametophyte development and male fertility.
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:19825572}; Multi-pass membrane protein {ECO:0000269|PubMed:19825572}.
Interaction partners:
- Putative non-specific lipid-transfer protein 14
- Magnesium/proton exchanger
- Cytochrome P450 703A2
- Transcription factor DYT1
- Transcription factor MYB35
Sequence:
MGSLRRSTSNRSRKKGTAVKMNRMPSSLSPPTPPCSAIVGGTGKSKKRRGGVCLWTRFDRTGFMEVAGCDKSTIIERSSVSAKDLRTAFSHSSKILAREKAIVLNLEVIKAVITSEQVMLLDSLRPEVLTLTDRLKHHFPRKDGPENILQASSHGHQEGGEEGLKSKLPFEFRVLEIAFEVFCSFVDSNVVDLETQAWSILDELTKKVSNENLKDLRSLKTSLTHLLARVQKVRDEIEHFLDDKEDMEDLYLTRKWIQNQQTEAASNSIVSQPNLQRHTSNRISTSMVTEEDDIDDMEMLLEAYFMQLEGMRNKILLMKEHIDSTEAYVKILQNSRRNGLIHLMMLVNIGNYAITAGTVVVNLFGMNIPIGLYSTPDIFGYVVWAVVALCIVLFIVTVGYAKWKKLLD
Protein: Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) (P16639)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).
Subcellular location: Cytoplasm.
Interaction partners:
- E3 ubiquitin-protein ligase UBR1
- E3 ubiquitin-protein ligase UBR2
- Protein N-terminal amidase
Sequence:
MSDRFVIWAPSMHNEPAAKCGYCHGNKGGNMDQLFALDSWAHRYMNKMDVVKIENCTIGSFVEHMDVATYDRMCNMGFRRSGKFLYKVDPLRNCCRLYTIRTAPQELNMTKELKKCISRFATRITSEDYCPAAVASSDFVGKIVNAEMNSKTFYTRFEPALYSEEKYHLFVKYQEKVHQDYNNSPKSFKRFLCDTPFGPEAVLGTQESWEQLNNWQRMKPGEKLKHMGPVHECYYYEGKLIAITVSDILPSGISSVYFIWDPDYSKWSLGKLSALRDLAIIQRTNLQYYYLGYYIEDCPKMNYKANYGAEVLDVCHSKYIPLKPIQDMISRGKLFVIGEEETKVTKELYLVDSETGRGEGFPTDNVVKYKNIAEEIYGVGGCAFKSANESALELKELYGIPYEEEDLDTIYHLKEHNGHAPNGIPNVVPGLLPLWELLDIMQSGKITDLEGRLFLFEIETEGIRPLINFYSEPPNVKKRICDVIRLFGFETCMKAVILYSEQM
Protein: Uncharacterized protein C6C3.02c (Q10307)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MPRRRSAAPPPRRAAPARSASTAAALPPRTMAPPPAPSRVQQAPPPTAVQGGSSPGFFGNLVSTAAGVGIGSAIGHTVGSVITGGFSGSGSNNAPADTSVPQSSYSNSVPEAAYGSAPPSTFASSAISEEAKNACKGDAKMFADCINEHEFSQCSYYLEQLKACQAMWSNQQ
Protein: Guanylate-binding protein 5 (EC 3.6.5.-) (GTP-binding protein 5) (GBP-5) (MuGBP-5) (Guanine nucleotide-binding protein 5) (Q8CFB4)
Organism: Mus musculus (Mouse)
Function: As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, inflammasome activating agents. Hydrolyzes GTP, but in contrast to other family members, such as GBP1 and GBP2, does not produce GMP (By similarity).
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000269|PubMed:18025219}; Lipid-anchor {ECO:0000250|UniProtKB:Q96PP8}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q96PP8}; Lipid-anchor {ECO:0000250|UniProtKB:Q96PP8}. Cytoplasm {ECO:0000250|UniProtKB:Q96PP8}.
Interaction partners:
- Guanylate-binding protein 2
- Guanylate-binding protein 1
- Signal transducer and activator of transcription 1
Sequence:
MAPEIHMPEPLCLIGSTEGHLVTNQEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKEKGFSVGSTVQSHTKGIWMWCVPHPQKPDHTLVLLDTEGLGDVEKDDKKNDTQIFALAILLSSTFVYNTMNKIDQGAIDLLHNVTELTDLLRTRNSSDSNQTEGEGPADMSFFPDLVWTLRDFFLDLQANGHAITSDEYLENSLKLKQGSDERTQTFNLPRLCIQKFFPVKKCFVFDAPALGSKLSQLPTLSNEELNSDFVQDLSEFCSHIFTQSKTKTLPGGIQVNGPRLESLVLTYVDAINSGALPSIENTVVTLARRENSAAVQKAIGHYDQLMSEKVQLPTETLQELLDLHRTCEREAIEIFRKHSFKDEGEFFQKELESLLSAKQDEICKKNADASAALCSTLLGSIFKPLEQEVAQEFYHKPGGHKLFLQRMEQLKANYRQQPGKGTQAEEVLQTYLNAKETVSRTILQTDQVLTDKEIQSKAEQERAEAARLEAQRLEAIRIQEEQRKAEMERQHQEQLRQIALEKARVAQEQQWILKQRAQEEADRIKAEQEAQLRALQQQLQHMREMNHHRRHHHDCVIS
Protein: Intermembrane transport protein PqiA (Paraquat-inducible protein A) (P0AFL9)
Organism: Escherichia coli (strain K12)
Function: Component of a transport pathway that contributes to membrane integrity.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:27795327}; Multi-pass membrane protein {ECO:0000269|PubMed:27795327}.
Interaction partners:
- Intermembrane transport lipoprotein PqiC
- Intermembrane transport protein PqiB
- Lipophilic envelope-spanning tunnel protein B
Sequence:
MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAWDAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTFFLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFVKLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIRQGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIMVTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHGKRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIMTMFSAMTFDPRLSWDRQPESEHEES
Protein: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (Gamma-9) (Q9UK08)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Guanine nucleotide-binding protein subunit beta-4
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- C-X-C chemokine receptor type 4
- 5-hydroxytryptamine receptor 7
- Melatonin receptor type 1B
- Apelin receptor
- C-C chemokine receptor type 5
- Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Sequence:
MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFCVLL
Protein: Neuroglobin (Nitrite reductase) (EC 1.7.-.-) (Q99JA8)
Organism: Rattus norvegicus (Rat)
Function: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9ER97}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q9ER97}. Note=Enriched in mitochondrial matrix upon oxygen-glucose deprivation. {ECO:0000250|UniProtKB:Q9ER97}.
Interaction partners:
- Cytoglobin
- Myoglobin
- Androglobin
- Cytochrome c, somatic
- Flotillin-1
Sequence:
MERPESELIRQSWRAVSRSPLEHGTVLFSRLFALEPSLLPLFQYNGRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLATLGRKHRAVGVRLSSFSTVGESLLYMLEKCLGPDFTPATRTAWSQLYGAVVQAMSRGWDGE
Protein: Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) (A0A8I6A4N6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364059}.
Interaction partners:
Sequence:
MKAQGETEESEKLSKMSSLLDRLHAKFNQSRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSLEQDLSKMAIMYWKATNATPLDKILHGSVGYLTPRSGGHLMNMKYYASPSDLLHDTTASPITLHEKNVPRSLGMNASVTIEGTSAMYKLPIAPLIMGSHPADNKWTPSFSAVTSANSVDLPACFFLKFPQPIPVSKAFVQKLQNCTGIPLFETPPTYLPLYELITQFELSKDPDPLPLNHNMRFYAALPGQQHCYFLNKDAPLPDGQSLQGTLVSKITFQHPGRVPLILNMIRHQVAYNTLIGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLYKGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNLPPASSPGVEEKRQSKPSLGHLPPIQVYSFSCLKRRQGYEVNFYLCAAAGL
Protein: Large ribosomal subunit protein mL44 (54S ribosomal protein L3, mitochondrial) (YmL3) (P36516)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Large ribosomal subunit protein mL49
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein uL23m
- Large ribosomal subunit protein uL16m
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein bL27m
- Small ribosomal subunit protein uS2m
Sequence:
MGIVLKRAIAAGMKPFPNSTWHWSRTIRPFSQHLSSTCFLQQSSRFTSKRYLHLSTLTQQEKRFLPESELAKYKEYYQGLKSTVNEIPESVASKSPSLRTLHKRLQLPNELTYSTLSRCLTCPSAKLPDKINNPTKGAAFVNTVPTNKYLDNHGLNIMGKNLLSYHVTKSIIQKYPRLPTVVLNAAVNAYISEAVLAHIAKYWGIEVETTSVLSRYLKMEPFEFTLGRLKFFNNSLNSKDGIELITGKNFSETSALAMSVRSIIAAIWAVTEQKDSQAVYRFIDDHIMSRKLDITKMFQFEQPTRELAMLCRREGLEKPVSKLVAESGRLSKSPVFIVHVFSGEETLGEGYGSSLKEAKARAATDALMKWYCYEPLAQQEPVIDPGTVVV