wanglab/gogpt-training-data huggingface dataset:
Protein: Interleukin-2 receptor subunit beta (IL-2 receptor subunit beta) (IL-2R subunit beta) (IL-2RB) (High affinity IL-2 receptor subunit beta) (p70-75) (CD antigen CD122) (P26896)
Organism: Rattus norvegicus (Rat)
Function: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P14784}; Single-pass type I membrane protein {ECO:0000255}. Cell surface {ECO:0000250|UniProtKB:P14784}.
Interaction partners:
- Interleukin-2
- Interleukin-15
- Interleukin 2 receptor, gamma, isoform CRA_a.
- Interleukin-2 receptor subunit alpha
- Interleukin-15 receptor subunit alpha
- Tyrosine-protein kinase
- Tyrosine-protein kinase JAK3
- Signal transducer and activator of transcription 5A
- Interleukin-7
- Signal transducer and activator of transcription 5B
Sequence:
MATVDLSWRLPLYILLLLLATTWVSAAVNDCSHLKCFYNSRANVSCMWSPEEALNVTSCHIHAKSDMRHWNKTCELTPVRQASWACNLILGPLPDSQSLTSVDLLSLSVVCWEEKGWRRVKTCTFHPFDNLRLIAPHSLQVLHIETRRCNISWEVSQVSHYVNPYLEFEARRRLLDRSWEDASVFSLKQRQQWIFLETLTPDTSYELQVRVIAQRGKTRTWSPWSQPMAFRTRPADPKEIFPLPWLRCLLLVLGCFFGFLSCVCVLVKCRYLGPWLKTLLKCHIPDPSEFFSQLSSQHGGDLQKWLSSPVPQSFFSPTGSAPEISPLEVLDRDSKTMQMLLFQKEKASSPSPSGHSQASCFTNQGYFFFHLSNALEIESCQVYFTYDPCMEEDVEEDGPRLPEESPLPPLLPFTGEQDDYCAFPPRDDLLLFSPSMSTPNTAYGNSITPEERPPLSLQEGLPSLASPDLMGLQHPLELELGDDGEGMSTNSSGQQASVPEAALMGTTKTEARPVLTLNTDAYLSLQELQAQDSAHLI
Protein: Tyrosine-protein kinase receptor ver-4 (EC 2.7.10.1) (Vascular endothelial growth factor receptor related 4) (Q21041)
Organism: Caenorhabditis elegans
Function: Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Protein ver-2
- Platelet-derived growth factor
- G-protein coupled receptors family 1 profile domain-containing protein
- Bromodomain adjacent to zinc finger domain protein 2
- G-protein coupled receptors family 1 profile domain-containing protein
Sequence:
MRVSLTEFLVLAQVVTTLQPITIKVDFHEVKHHESIGDYVELVEGKNRDISLTCYGQHKNLKIEPPKREEHAGFPEIGIRTSAEWKKNEYWFLLKNVRQCDTGSYYCVSDEFKESMLQNTVHIFVRKLDIFVPLKTIYHEHNGSEIIIPCKTTKFVDTKNVELYVNQVKLNSALQGYDQRYGFKLTKNMYTMKPNSTVFFECKYTNDSNQDLDYYISNSDPDATLIDQYFFYWEKSNDVPYVGNNYSITCHLVYIGSDSLRPLNHQEIVLECPQNQCDGGYNNQSAHEIEKRSSGLRFGDPSSQDIVEKNTMLRYDRLSVYDRKTSRTVNFQNLTSEDSGIYRCTWRNRSKTNIVLDYDLNFNQKGTQIKIIETSKQRLKMRKNESTLLFVKFAVFPINKKNYTAKWSRLYNSTVEGGQQVETIRNGFFRQITTKTSGRNVFLETLNLKSPKIEMSGIYVLSISNMDIVQQVKWIIEVENDEPNAQLTIRDPLTLNISNQLFLPLNTNLSIFCLAVSSSPTDVIFEYRTDENEWFRGFYKNKLRKIDDTFEKGFIYNFVLAKRTDFKCINVKKKKTSTKFITVTSNANKTFHEIEKSVNATKTEPSDIIFEGDNVRLTCVVPYGAVEFDVFWKFENPKMLKYTTFPAMHPVKDRYKRVILNVRNITIDFTGTYYCIVKNKEFEHRFETSISVEKVSPPFLLNNNSRSIISASNGQMFDINCKVNGVPTPDYTWFKDGYPYTKGKVIGNALHVSKAEKRDNGIFWCSATNRAGTTIDYIEVKVAGASSSSFFWLFITFFAFVVVGIVVSLLWKLFGQKDLKPSELSLNNLKRATDEYQKYTVSEKINNLPVEERIDYLTYNEDYEIDLENLEILETLGSGQFGIVKKGYLNMASSKNFGFESRLSVAIKSSTDSSNMELQKMFFEELKLMCAIPKHPNVLSLVGAVTKNMEIGELFIVTELIDGGNLREFLRERRDVFANELVEKGYIFLTNVRENVPKREVEKEQLLIDEFNSLCTSDLLSIGLQIANGMDWLANIPCVHRDLACRNVLISKTKIIRIADFGLAKKHTDKAYYRVRESLDTPLPVRWMPLESITDLTFTQKSDVWSYGICLYEIFTLGGTPYPDCPNFSLVEYIKTGNINKRPSNCHKDVYKIMKMCWQASPDDRPTFAECIKLFKNHIQYFASKLLQQIEKDLECEKNNQQKFHYWVQKPTQLFF
Protein: Aromatic peroxygenase (B9W4V8)
Organism: Coprinellus radians (Coprophilous mushroom) (Coprinus radians)
Function: Aromatic peroxidase that oxidizes aryl alcohols into the corresponding aldehydes and then into the corresponding benzoic acids. Catalyzes the regioselective peroxide-dependent hydroxylation of naphthalene to 1-naphthol and to a far lesser extent 2-naphthol via a naphthalene 1,2-oxide intermediate. Halogenates phenol to 2-bromophenol and 4-bromophenol. Oxidizes the sulfur-containing heterocycle dibenzothiophene to yield sulfoxidation products, and trace amounts of ring-hydroxylation products.
Interaction partners:
Sequence:
VPGGLXPPPEYVGPKLVNDADHPWEPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAIVEGFNFNYEGAVFVTYFAHIVDGNLVTDLLSIGGKTNLTGEDTGAPAIIGGLNTHSVFEGDASMTRDDFHFGDNHSFNQTLFDQFVEYSNTYGGGFYNQEVAGHLRRRRIEQSIATNPEFDFTSPRFFTAFAESSFPYSFFVDGRITERPGGLSMENATLFFRDHKMPDDFWRNVNGEMTFTGTPDPNSAPSNLALGH
Protein: Transmembrane protein 185A (Protein FAM11A) (Q8NFB2)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, dendrite {ECO:0000250}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- AF4/FMR2 family member 2
- Fragile X messenger ribonucleoprotein 1
Sequence:
MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDNEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD
Protein: Nitrogen regulatory protein GLN3 (P18494)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Positive nitrogen regulatory protein. Required for the activation of transcription of a number of genes (including the allantoin pathway genes) in response to the replacement of glutamine by glutamate as source of nitrogen. Binds the nitrogen upstream activation sequence of GLN1, the gene encoding glutamine synthetase. URE2 may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine.
Subcellular location: Nucleus.
Interaction partners:
- Transcriptional regulator URE2
- General control transcription factor GCN4
- Serine/threonine-protein kinase TOR1
- Transcriptional activator protein DAL81
- Transcriptional regulatory protein GAT1
- Type 2A phosphatase-associated protein 42
- Serine/threonine-protein phosphatase PP1-1
- Glutamine synthetase
- Retrograde regulation protein 3
- Ammonium transporter MEP2
Sequence:
MQDDPENSKLYDLLNSHLDVHGRSNEEPRQTGDSRSQSSGNTGENEEDIAFASGLNGGTFDSMLEALPDDLYFTDFVSPFTAAATTSVTTKTVKDTTPATNHMDDDIAMFDSLATTQPIDIAASNQQNGEIAQLWDFNVDQFNMTPSNSSGSATISAPNSFTSDIPQYNHGSLGNSVSKSSLFPYNSSTSNSNINQPSINNNSNTNAQSHHSFNIYKLQNNNSSSSAMNITNNNNSNNSNIQHPFLKKSDSIGLSSSNTTNSVRKNSLIKPMSSTSLANFKRAASVSSSISNMEPSGQNKKPLIQCFNCKTFKTPLWRRSPEGNTLCNACGLFQKLHGTMRPLSLKSDVIKKRISKKRAKQTDPNIAQNTPSAPATASTSVTTTNAKPIRSRKKSLQQNSLSRVIPEEIIRDNIGNTNNILNVNRGGYNFNSVPSPVLMNSQSYNSSNANFNGASNANLNSNNLMRHNSNTVTPNFRRSSRRSSTSSNTSSSSKSSSRSVVPILPKPSPNSANSQQFNMNMNLMNTTNNVSAGNSVASSPRIISSANFNSNSPLQQNLLSNSFQRQGMNIPRRKMSRNASYSSSFMAASLQQLHEQQQVDVNSNTNTNSNRQNWNSSNSVSTNSRSSNFVSQKPNFDIFNTPVDSPSVSRPSSRKSHTSLLSQQLQNSESNSFISNHKFNNRLSSDSTSPIKYEADVSAGGKISEDNSTKGSSKESSAIADELDWLKFGI
Protein: Histone H3 (C1BG88)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDANLCAIHAKRVTIMPKDIQLARRIRGERA
Protein: Tectonic-3 (Q8R2Q6)
Organism: Mus musculus (Mouse)
Function: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation (By similarity). Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- B9 domain-containing protein 1
- Coiled-coil and C2 domain-containing protein 2A
- Tectonic-1
- Transmembrane protein 216
- Tectonic-2
- Meckelin
- B9 domain-containing protein 2
- Jouberin
- Tectonic-like complex member MKS1
- Centrosomal protein of 290 kDa
Sequence:
MCTLQLHLLLLVVLMLSETARPQPSSTARAFPTSWGLEPVTPEVPTSAPPDSSESPTPWTLSMPVNATTDPFPALPICVCDLTPGTCDLNCCCDKDCDLLHPRTVFSFCLPGSVRSSSWVCVDNSLMFRSNSPFPSRVFTDSSGTTQFCVRVNNSKANYFQKLQTVNATNFQALAAEFGGQSFPSMPPETQPPVLFYRAGDPILTYYPSWSVVSLLRQPAAVGAGGLCAESNPAGFLESKSTTCPRFFRDLASSCTSEPALDAASYYNFRVLKVPRGVTDLQNMKFQVPVTLASQASPPLLAGNTCQNIVSQVVYEIETNGTFGIQKVSVSFRQTNLTVKPGVSLQQDFIVHFRAFQQRKAAAPAAPRSGNPGYLTGKPLLVLTGDTSHSMTLLQSEGNGLCSAKRHAVQFGVNAVSGCQLRPREVNCSHLQEEVYQTLHGRPRPEHVAVFGNADPAQRGGWTRILSRDCSVSAVNCTSCCLIPVSLEIQVLWAHLGLQSNPQAHVAGARFLYQCKSVQEHQRGIEVSLTTLVNFVDITQKPEPPRDQPRIDWKLPFDFFFPFKAALSRGASVQKDSLVLILCVLLLGLLNSQTK
Protein: Nuclear receptor subfamily 2 group F member 1 (Ovalbumin upstream promoter-transcription factor I) (F1DAL7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MAMVVSSWRDPQDDVAGGNPGGPNPAAQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
Protein: Leukotriene A(4) hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (A0A140VK27)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU361141}.
Interaction partners:
Sequence:
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD
Protein: LIM and SH3 domain protein 1 (LASP-1) (Q99MZ8)
Organism: Rattus norvegicus (Rat)
Function: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
Subcellular location: Cytoplasm, cell cortex {ECO:0000269|PubMed:10806114}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10806114}. Note=Associated with the F-actin rich cortical cytoskeleton.
Interaction partners:
- Zyxin
- Lipoma-preferred partner homolog
- Palladin
Sequence:
MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGIEPERREAQDSSSYRRPTEQQQPQPHHIPTSAPVYQQPQQQQVTPSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI
Protein: tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.90) (pp35) (tRNA-dihydrouridine synthase 4-like) (O95620)
Organism: Homo sapiens (Human)
Function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Interaction partners:
- B-cell receptor-associated protein 29
- Conserved oligomeric Golgi complex subunit 5
- G-protein coupled receptor 22
Sequence:
MKSDCMQTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKIIKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEETPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNALSSTSAIIDYLTDHYGI
Protein: Magnetosome protein MamC (A0L9X3)
Organism: Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)
Function: Probably helps control the size of magnetite crystals; in vitro synthesis of magnetite yields larger and more well-developed magnetite crystals in the presence of purified MamC. Binds Fe(3+). The lumenal domain probably binds magnetite crystals, affecting crystal size and shape (Probable). Purified MamC self-assembles into micelles in the presence of ferric chloride hexahydrate (FeCl(3).6H(2)O); both oxygen and iron are present in the proteinaceous micelles. Whether this is relevant in vivo is unknown (Ref.3).
Subcellular location: Magnetosome membrane {ECO:0000269|PubMed:24760293}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAAFNLALYLSKSIPGVGVLGGVIGGSAALAKNLKAKQRGEITTEEAVIDTGKEALGAGLATTVSAYAAGVVGGGLVVSLGTAFAVAVAGKYAWDYGMEQMEAKLQEKKHQEQGGQTYGDNPDPFDPQELETP
Protein: Large ribosomal subunit protein bL35m (39S ribosomal protein L35, mitochondrial) (L35mt) (MRP-L35) (Q9NZE8)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042}.
Interaction partners:
- Large ribosomal subunit protein uL15m
- Large ribosomal subunit protein mL39
- Large ribosomal subunit protein bL9m
- Large ribosomal subunit protein bL20m
- Large ribosomal subunit protein mL65
- Large ribosomal subunit protein mL51
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein mL38
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein mL50
Sequence:
MAASAFAGAVRAASGILRPLNILASSTYRNCVKNASLISALSTGRFSHIQTPVVSSTPRLTTSERNLTCGHTSVILNRMAPVLPSVLKLPVRSLTYFSARKGKRKTVKAVIDRFLRLHCGLWVRRKAGYKKKLWKKTPARKKRLREFVFCNKTQSKLLDKMTTSFWKRRNWYVDDPYQKYHDRTNLKV
Protein: Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas) (Q63767)
Organism: Rattus norvegicus (Rat)
Function: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion (By similarity). Implicated in induction of cell migration and cell branching (By similarity). Involved in the BCAR3-mediated inhibition of TGFB signaling (By similarity).
Subcellular location: Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q61140}. Cytoplasm {ECO:0000250|UniProtKB:Q61140}. Cell projection, axon {ECO:0000250|UniProtKB:Q61140}. Note=Unphosphorylated form localizes in the cytoplasm (By similarity). Localizes to focal adhesion sites following integrin engagement (By similarity). {ECO:0000250|UniProtKB:Q61140}.
Interaction partners:
- Paxillin
- Proto-oncogene tyrosine-protein kinase Src
- Focal adhesion kinase 1
- Adapter molecule crk
- Vinculin
- Talin 1
- Crk-like protein
- Protein-tyrosine kinase 2-beta
- Talin 2
- Dedicator of cyto-kinesis 1
Sequence:
MKYLVSVGAGPARRAGGLEDVSWGPRVSRRPQSYRAARHVNESLPRSAFRVPAAHGASVTPSAALGSGLPETQPEAVCRGTEKPRFAEGCKPAASRDKNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAAPGPGPPATPPQPQPSLPQGVHTPVPPASQYSPMLPTAYQPQPDNVYLVPTPSKTQQGLYQAPGPNPQFQSPPAKQTSTFSKQTPHHSFPSPATDLYQVPPGPGSPAQDIYQVPPSAGTGHDIYQVPPSLDTRSWEGTKPPAKVVVPTRVGQGYVYEASQAEQDEYDTPRHLLAPGSQDIYDVPPVRGLLPNQYGQEVYDTPPMAVKGPNGRDPLLDVYDVPPSVEKGLPPSNHHSVYDVPPSVSKDVPDGPLLREETYDVPPAFAKPKPFDPTRHPLILAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGSVIDDGVYAVPPPAEREAPTDGKRLSASSTGSTRSSQSASSLEVVVPGREPLELEVAVETLARLQQGVSTTVAHLLDLVGSASGPGGWRSTSEPQEPPVQDLKAAVAAVHGAVHELLEFARSAVSSATHTSDRTLHAKLSRQLQKMEDVYQTLVVHGQVLDSGRGGPGFTLDDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKAPGPGPEGSSSLHLNPTDKASSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGNIVRQGKGQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLVPGRTGGLGPSDRQLLLFYLEQCEANLTTLTDAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSKVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVDRVKELGHSTQQFRRVLGQLAAA
Protein: SCAN domain-containing protein 1 (Q9NZG6)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187}.
Interaction partners:
Sequence:
GRREARDFRFRLPQALRWCRRSAEHTATGQRVTPGAGVMAATEPILAATGSPAAVPPEKLEGAGSSSAPERNCVGSSLPEASPPAPEPSSPNAAVPEAIPTPRAAASAALELPLGPAPVSVAPQAEAEARSTPGPAGSRLGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLLAILPEAARARRIRRRTDVRITG
Protein: FAD-binding FR-type domain-containing protein (G5EB25)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Altered inheritance of mitochondria protein 24
Sequence:
MGRYPLKSYFAPSKLFFYTWFWGAHIAIFAYGWYHQAKSEPLSPLNVLSYSVWISRGAGLVLTVDGTLILLPMCRNLVRFLRPKLRWLPLDENIWFHRQVAYATLVFTILHVAAHYVNFYNIERKQLRPETALQIHYAQPAGVTGHVMLFCMMLMYTTAHHRIRQQSFETFWYTHHLFIPFLLGLYTHATGCFVRDSAEPYSPFAGERFWKHCIGYQGWRWELVAGFFYLCERLWREIRALRETEIVKVVRHPYDAMEIQFRKPGFKYKPGQWLFIQVPEVSNTQWHPFTITSCPFDDYVSIHVRQVGDFTRALGDALGCGPAQARDLEGLDPMGMYEVALQNGQQMPKLRVDGPYGAPAEDVFENEIAVLIGTGIGVTPWASILKNIWHLRASPDPPRRLRRVEFIWVCKDTTSFEWFQALLSSLEAQSASDAAYQGVSEFLRIHIYLTQRLDQDTTTNIYLNSVGQELDPLTELKSRTNFGRPDFKRLFTAMRNGLQDQSYMRGLHTHSRTEIGVYFCGPNVAARQIKAAASSASTNEVKFKFWKEHF
Protein: Podocin (Q9NP85)
Organism: Homo sapiens (Human)
Function: Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum {ECO:0000269|PubMed:23648087}.
Interaction partners:
- Kin of IRRE-like protein 1
- Nephrin
- CD2-associated protein
- Short transient receptor potential channel 6
- Tight junction protein 1
- Alpha-actinin-4
- Cadherin-3
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
- Kin of IRRE-like protein 3
- Protocadherin Fat 1
Sequence:
MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAATVVDVDEVRGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEIVTKDMFIMEIDAICYYRMENASLLLSSLAHVSKAVQFLVQTTMKRLLAHRSLTEILLERKSIAQDAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCLSSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML
Protein: Multidrug resistance protein 1 (Benomyl resistance protein 1) (Q5ABU7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Plasma membrane multidrug efflux pump that confers resistance to numerous chemicals including azoles such as fluconazole, voriconazole, and benztriazoles, as well as to benomyl, cycloheximide, methotrexate, 4-nitroquinoline-N-oxide, sulfometuron methyl, cerulenin, and brefeldin A.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22587419}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Multidrug resistance protein CDR2
- Pleiotropic ABC efflux transporter of multiple drugs CDR1
- Lanosterol 14-alpha demethylase
- Transcription factor TAC1
- Sterol uptake control protein 2
Sequence:
MHYRFLRDSFVGRVTYHLSKHKYFAHPEEAKDYIVPEKYLADYKPTLADDTSINFEKEEIDNQGEPNSSQSSSSNNTIVDNNNNNDNDVDGDKIVVTWDGDDDPENPQNWPTLQKAFFIFQISFLTTSVYMGSAVYTPGIEELMHDFGIGRVVATLPLTLFVIGYGVGPLVFSPMSENAIFGRTSIYIITLFLFVILQIPTALVNNIAGLCILRFLGGFFASPCLATGGASVADVVKFWNLPVGLAAWSLGAVCGPSFGPFFGSILTVKASWRWTFWFMCIISGFSFVMLCFTLPETFGKTLLYRKAKRLRAITGNDRITSEGEVENSKMTSHELIIDTLWRPLEITVMEPVVLLINIYIAMVYSILYLFFEVFPIYFVGVKHFTLVELGTTYMSIVIGIVIAAFIYIPVIRQKFTKPILRQEQVFPEVFIPIAIVGGILLTSGLFIFGWSANRTTHWVGPLFGAATTASGAFLIFQTLFNFMGASFKPHYIASVFASNDLFRSVIASVFPLFGAPLFDNLATPEYPVAWGSSVLGFITLVMIAIPVLFYLNGPKLRARSKYAN
Protein: Phosphoserine aminotransferase (PSAT) (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (Serine requiring protein 1) (P33330)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Interaction partners:
- D-3-phosphoglycerate dehydrogenase 1
- D-3-phosphoglycerate dehydrogenase 2
- Phosphoserine phosphatase
- Threonine synthase
- Serine hydroxymethyltransferase, cytosolic
- Putative mitochondrial cysteine synthase
- Serine hydroxymethyltransferase, mitochondrial
- Homoserine kinase
- Low specificity L-threonine aldolase
- Homoserine dehydrogenase
Sequence:
MSLEREEPQHFGAGPAQMPTPVLQQAAKDLINFNDIGLGIGEISHRSKDATKVIEDSKKHLIELLNIPDTHEVFYLQGGGTTGFSSVATNLAAAYVGKHGKIAPAGYLVTGSWSQKSFEEAKRLHVPAEVIFNAKDYNNGKFGKIPDESLWEDKIKGKAFSYVYLCENETVHGVEWPELPKCLVNDPNIEIVADLSSDILSRKIDVSQYGVIMAGAQKNIGLAGLTLYIIKKSILKNISGASDETLHELGVPITPIAFDYPTVVKNNSAYNTIPIFTLHVMDLVFQHILKKGGVEAQQAENEEKAKILYEALDANSDFYNVPVDPKCRSKMNVVFTLKKDGLDDQFLKEAAARHLTGLKGHRSVGGFRASIYNALSVKAVQNLVDFIKEFAEKNA
Protein: Methyltransferase domain-containing protein (O07251)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- SAM-dependent methyltransferase
- HTH-type transcriptional regulator Rv0324
- Putative gluconeogenesis factor
Sequence:
MVATDFSDVAVAQLRRSAQARGVSARVQPIVHDLRQPLPVKTGSIDGAFAHMALCMALSTSEIHAVVAEVGRVLRPGGKFIYTVRHTGDAHYGAGQAHGDDIFECAGFAVHFFRRELVARLATGWVLEEVHDFEEGELPRRLWRVTVTKPA
Protein: Toll-like receptor (Q6P690)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU363040}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU363040}.
Interaction partners:
Sequence:
MVKSLWDSLCNMSQDREPIVESFHFVCTLALIVGSMTQFSDELESVVDYSNKNLTHVPKDLSPSTKSLSLSQNSISDLQMSDISFLSELRVLRLSHNRIRRLDFGVFLLNRDLEYLDVSHNQLQNISCCPMVNLKHLDLSFNDFEVLPVYKEFGNLRKLSFLGLSAAKFRQLDLLPISHLHLSCVLLDLVNYQIKDGETESLQVPNTNVLHLVFHPNSLFSVQVNISVNALGCLQLSNIKLNDENCQSLIIFLSELTRGPTLLNLTLQHIETNWKCFVRLLQFLWPRPVEYLNIYNLTITESISRETFIYVETVLKSLKIEHVTNQVFLFVKDALYSVFAEMNIRMLTLSDTPFIHMVCPEFPSTFAFLNFTQNVFTDSIFQGCSTLKRLETLILQRNGLKNLFKVALMTKTMSSLETLDVSLNSLNSHVYDRTCAWAESIRVLNLSSNVLSDSVFRCLPPKVKVLDLHNNRIVSIPKDVTHLQALQELNVASNFLTDLPGCGAFSSLSVLVIDHNSVSHPSSDFFQSCQNIRSITAGNNPFRCTCELREFVKNIGQASREVVEGWPDSYRCDYPDSIKGTPLQDFHMSPLSCDTILLTVTIGATLLLLAAIGASLCLYFDLPWYLRMLWQWTQTRHRARNIPLEELQRNLQFHAFVSYSEHDSAWVKNELLPNLEKDDIRVCLHERNFVPGKSIVENIIHFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPIQQNNIPSRYHKLRALMAQRTYLEWPIEKGKRGLFWANLRASFIMKLALVNENDVKT
Protein: DNA repair protein-like protein (F4JA85)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRVPKDGFSGTGIFPHPFHKMIMKPHHFEILNFLYKNLVVENSNGCIIAQTPLSEKTFLMISFIYGYLEKHPNSKSLFVLPKWVLNLEVLKRWIKTWSIIFLGAKQFSNIVSDNSGAEASDSCRDILLNILSVVVFDRGTDPRNEMMSFLKVVSRIKTPHKVLLTGSLYQNNIKEVFNILDVAFPEFLKHNQIGKNFRKLLNVEADGPSTNLKMPLFDKLEEALLSQDSDHGDKICYLTELKMLTNKVIYNHKGECLLEVPGLMDFTVVLKPTSSQKSAWEVERKSNGKGFKKYSTLSGIMLHPLLCAFSDRAKGLPAPNEDEMDEM
Protein: Uncharacterized HTH-type transcriptional regulator PH0140 (O57880)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Interaction partners:
- Uncharacterized protein
Sequence:
MITVPHSRKVELDEIDRAILRLLQEDGRMSYSEISRRINVPESTVRARVNRLVKEGVIRKFAALINPFKAGYEIVAFIAVDAEPAKVKQVVEELAKFPEVDVLGIVTGAHDIFMQVTVKDLQELERFILEKMAKIDGIKSTETSILTSVKKWGYARVF
Protein: TAF-like protein (Q5UEC2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDSNMEPWSFALNFDDSDKSSDNESHSSTRSSSRSSDTSIDTSSVEKEPASVIESQSVPGGSYDIISKTNMLQFVQKIDANSSLDDQGCDMMARIADAFVNDVSMRMVKLAKYRKSDVSVLDLKFILKREFNMEFPIE
Protein: Small RNA 2'-O-methyltransferase (EC 2.1.1.386) (HEN1 methyltransferase homolog) (DmHen1) (piRNA methyltransferase) (Q7K175)
Organism: Drosophila melanogaster (Fruit fly)
Function: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of selected small RNAs. Mediates 2'-O-methylation of piRNAs, single-stranded siRNAs and long hairpin RNA genes (hpRNAs). Methylation protects the 3'-end of small RNAs from tailing and trimming and could constitute a recognition signal for appropriate argonaute machineries.
Interaction partners:
- Protein piwi
- Mitochondrial cardiolipin hydrolase
- Endoribonuclease Dcr-2
- Protein aubergine
- Protein argonaute-1
- LD06392p
- Exonuclease mut-7 homolog
- Probable ATP-dependent RNA helicase spindle-E
- GH09064p
- Protein Loquacious
Sequence:
MFSHKFICGSLTKMTETGITFDPPVYEQRYCATIQILEDARWKDQIKKVVEFGCAEMRFFQLMRRIETIEHIGLVDIDKSLLMRNLTSVNPLVSDYIRSRASPLKVQILQGNVADSSEELRDTDAVIAIELIEHVYDDVLAKIPVNIFGFMQPKLVVFSTPNSDFNVIFTRFNPLLPNGFRHEDHKFEWSRDEFKNWCLGIVEKYPNYMFSLTGVGNPPKEYESVGPVSQIAIFVRKDMLEMQLVNPLVSKPNIDKESIPYKLIHTVEYPFYVDTRTEKEKLWTEVQIELQRFKRQFESSEIEEGTYQDTCNMPIAFLLDRLEHVGATKERIEELLLENNLTVENECVLIVSSDQESEWSDPYKFSDRSSQDDALVDQEQEEERWDQGPES