wanglab/gogpt-training-data huggingface dataset:
Protein: Forked, isoform J (M9MSB3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell projection, stereocilium {ECO:0000256|ARBA:ARBA00004645}.
Interaction partners:
Sequence:
MASCAPVIVWNGAQFTASSRELEQLRRDYGLDARMLEATLVPRYKRHKPQAAARNDHVRVTKEQQSDWILKQDRSTNVSQVNFHPWAGAHFDLVPWRRTRSALDLTAVEDYNHGLVDPKSLKGLEKLELRQQRRRLQRARSTHQGLRRLVRVRLIFSIELRHKRMEVLRKSSLPVRVFEQRFALSENESAAYERILLDANAGVDQHVGYFSKRQVVTSNRESNEELVVDFASETEADEKADEQPEKEEAQYATIAPAEKGGSAAVPDKESGQVPCVKCRDIAIKLRTINDYALNSNLHLSHNTKLNNLHSNKLLHSNQSHSSSINPSTRMHSHQLDSYLGGVGSMMNLGGMGQVGQMYHPGSVSGSERPNGGALALHYAAARGCLDCVQLLVAASVDICANTQMDNDVTPVYLAAQEGHLEVLKFLVLEAGGSLYVRARDGMAPIHAASQMGCLDCLKWMVQDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSLDKYGKSPINDAAENQQVECLNVLVQHGTSVDYNGKSSSQRHKSQQQLHQQHQQQQQQQQQQHLSSSCNSNSNSSKQTSRSNTIKSKSSSTLSSDVEPFYLHPPALAGGSGGSGMGLGMGMGMGMGMSMGLGISRKNSDALYSQQSRSSSEKLYNGSSSLGGNPGGNSSSGGGGVGGGGGSGGALLPNDGLYVNPMRNGGMYNTPSPNGSISGESFFLHDPQDIIYNRVRDLFVDSDCSSSVKQHGKSHAHQLLQSKAGNAMTIQADVHSSSSGAGSGSDESVSISSSFNSPKQQQQLRSQSFNRHGSSSNISASGNIKNNNYKAHKGKPSNQNGGGDHDYEDIYLVREESRKQHQQQQQHQLQQQQQLQHQATQQQQQQQQQQQQLQHKYNVGRSRSRDSGSHSRSASASSTRSTDIVLQYSNHHLNNKRNMNNNSNMNNSSSNIAQSSSSNNNNNSLLNRNKSHSIIGLHSSKYESSLKDNYSAKNVNLKNQLLNGGIKSDTYESVCPPEDVAERTKQTHKNSMIRNNLADASSNNNTSGSINNISNIGNMNGGNQSSRNLKRVSSAPPMQNLAVVNGPPPPPLPPPLRAPVQQQRNNLSVDQPNSMTGNNGIYKKNVFGPNQGPTNANGTGGAAPPPVPAPNPVATEAVDSDSGLEVVEEPSLRPSELVRGNHNRTMSTISANKKAKLLNAGSTNGSSIAASSDDSQSRYGGSVHAANGSAANGHFYGYSEGNKNQGSNGNGNGNGNGGGGNYHSHPNQPHYATGQPHQYTPSLYGGGSSAEDHYELTQQQQQIYGETHLPSGQRTGGPNLVNKQLVLPFVPPSFPNKSQDGVTHLIKPSEYLKSISIDKRSCPSSARSTDTEDYMQIQIAQQQSHPHQHQHHPHPHPHPHHPHQLHGMGEQPPLPPPPPPLPHGMLPPQPPMGPPMGVAGGQDATMSGKSHKPKKPHGSAPNSQDTATRKQHQPLSAISIQDLNSVQLRRTDTQKVPKPYQMPARSLSMQCLTSSTETYLKSDLIAELKISKDIPGIKKMKVEQQMASRMDSEHYMEITKQFSGNNYVDQIPERDQAGNAIPDWKRQMMAKKAAERAKKDFEERMAQEAESRRLSQIPQWKRDLLARREETENKLKAAIYTPKVEENNRVADTWRLKNRAMSIDNININLAGMEQHYQQIQFQQKQQQLQLGNKENHVDPKGADQDQEHGVGIGSGVGNANSGVIGGQELIDPSEGSQGRAEEEEDNIIPWRAQLRKTNSRLSLI
Protein: V-type proton ATPase subunit S1 (Vacuolar H(+) ATPase AC45 accessory subunit) (Q7JR49)
Organism: Drosophila melanogaster (Fruit fly)
Function: Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q15904}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- ATPase H
- V-type proton ATPase subunit G
- V-type proton ATPase subunit d 1
- V-type proton ATPase subunit B
- V-type proton ATPase subunit C
- V-type proton ATPase subunit E
- V-type proton ATPase 16 kDa proteolipid subunit c
- V-type proton ATPase subunit H
- V-type proton ATPase subunit a
- Probable V-type proton ATPase subunit d 2
Sequence:
MLWKSLIALCVIGAAVAEQTPVFLWGANSVAKPSLKTVSQVEFAEQLAALLEDHMVVAFEENGLSSKDFLCSNSQAQSCYAQLQGVSPKTYYTSVENPSEALRSVAAKREHNSIDASGKLTTPAKCAVGTALFVTFEDAAESREASLESHDAAIAAISKQFECKVAYLYLAAPSTAPVVQRRTRRDTAATTGGIMWKSTNQFQIFYTALLYNGNPITVTDLKLTNSSSTKLSVVMDTSVADKPITFDVVYNGGYFSLSNLVYDNNNFRSSGVNAPTTFSYSCGNLTLESAAVNNMYNTLSFKSLQLQAPFDGTYKEDFPFGDSWDCVGFVTPGILMGLFVVALLLVIMFVGVCWMMDINTMDRFDDPKGKTITINAAAE
Protein: Uncharacterized protein (Q4GYQ8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHVVSEIQRRPNKARLKSEKYIVHFYSLCTLVQLVCLIVFVTQFDMASNRTFTSSLWVENPFELAPSLVWLSKRCSHSVQNERVFAFTGVSVNISDKVVGVMFAALATEMHATFFLAVTALLVGAINRYAVKANFFEFKWRNFNVRKDCFFATEIVLISALLHSVLLAEDTHRMLHDYLDHCNTRSRGFLPYCSTVPMIIFITFAFATYFFGFFVYMWNALPKYGIMSDEEVVEYREWLRRREESVAEVKRMEEEVRRANTRLQLMLENEKNMKLGKSTYQSRRPTIRREAYGSKQGDDAQQWGT
Protein: Ubiquinol-cytochrome c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19) (Q9BRT2)
Organism: Homo sapiens (Human)
Function: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability.
Subcellular location: Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space {ECO:0000250}. Mitochondrion matrix {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}. Note=Predominantly expressed in the mitochondrial inner membrane. {ECO:0000250}.
Interaction partners:
- Ubiquinol-cytochrome c reductase complex assembly factor 1
- Cytochrome c oxidase assembly protein COX20
- Cytochrome b
- Ubiquinol-cytochrome-c reductase complex assembly factor 3
Sequence:
MAASRYRRFLKLCEEWPVDETKRGRDLGAYLRQRVAQAFREGENTQVAEPEACDQMYESLARLHSNYYKHKYPRPRDTSFSGLSLEEYKLILSTDTLEELKEIDKGMWKKLQEKFAPKGPEEDHKA
Protein: Sodium/potassium-transporting ATPase subunit alpha (A0A060XA63)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU362084}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362084}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit beta
- Sodium/potassium-transporting ATPase subunit beta
- Sodium/potassium-transporting ATPase subunit beta-1
- Sodium/potassium-transporting ATPase subunit beta-2
- Potassium-transporting ATPase subunit beta
- Potassium-transporting ATPase subunit beta
- Sodium/potassium-transporting ATPase subunit beta
- Sodium/potassium-transporting ATPase subunit beta
- Uncharacterized protein
- Nucleoside-diphosphate kinase
Sequence:
MKGAPERILDRCSTILIQGKEQPLDDELKEAFQNAYEELGGLGERVLGFCHFQLPDDQFAEGFQFDCEEVNFPTENLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLKIPVSEVNPRDAKACVVHGGELKDLSAEQLDDILAHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEEAENDIMKRQPRNPKTDKLVNERLISIAYGQIGMMQATAGFFTYFVILAENGFLPMDLLGMRVDWDNKIMNDMEDSYGQQWTYERRKIVEFTCHTAFFASIVVVQWADLIICKTRRNSILQQGMKNRILIFGLFEETALAVFLSYCPGMDVALRMYPLKPCWWFCALPYSLLIFLYDEGRRYILRRNPGGWVEQETYY
Protein: Serine/threonine-protein kinase Warts (EC 2.7.11.1) (Q9VA38)
Organism: Drosophila melanogaster (Fruit fly)
Function: Negative regulator of Yorkie (Yki) in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. The Hippo/SWH signaling pathway inhibits the activity of the transcriptional complex formed by Scalloped (sd) and Yki and the target genes of this pathway include cyclin-E (cycE), diap1 and bantam. Inhibits nuclear localization of Yki. Regulates salivary gland degradation in a PI3K-dependent manner and Yki- and Sd-independent, mechanism.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:18245354}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18245354}. Note=Colocalizes with mats and cyclin E at the centrosome.
Interaction partners:
- Transcriptional coactivator yorkie
- MOB kinase activator-like 1
- Serine/threonine-protein kinase hippo
- Scaffold protein salvador
- LIM domain-containing protein jub
- Dachs, isoform E
- Protein kibra
- MOB kinase activator-like 2
- Cadherin-related tumor suppressor
- Protein expanded
Sequence:
MHPAGEKRGGRPNDKYTAEALESIKQDLTRFEVQNNHRNNQNYTPLRYTATNGRNDALTPDYHHAKQPMEPPPSASPAPDVVIPPPPAIVGQPGAGSISVSGVGVGVVGVANGRVPKMMTALMPNKLIRKPSIERDTASSHYLRCSPALDSGAGSSRSDSPHSHHTHQPSSRTVGNPGGNGGFSPSPSGFSEVAPPAPPPRNPTACSAATPPPPVPPTSQAYVKRRSPALNNRPPAIAPPTQRGNSPVITQNGLKNPQQQLTQQLKSLNLYPGGGSGAVVEPPPPYLIQGGAGGAAPPPPPPSYTASMQSRQSPTQSQQSDYRKSPSSGIYSATSAGSPSPITVSLPPAPLAKPQPRVYQARSQQPIIMQSVKSTQVQKPVLQTAVAPQSPSSASASNSPVHVLAAPPSYPQKSAAVVQQQQQAAAAAHQQQHQHQQSKPPTPTTPPLVGLNSKPNCLEPPSYAKSMQAKAATVVQQQQQQQQQQQQVQQQQVQQQQQQQQQQLQALRVLQAQAQRERDQRERDQRERERDQQKLANGNPGRQMLPPPPYQSNNNNNSEIKPPSCNNNNIQISNSNLATTPPIPPAKYNNNSSNTGANSSGGSNGSTGTTASSSTSCKKIKHASPIPERKKISKEKEEERKEFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQNDRTFHGFFEFTFRRFFDDKQPPDMTDDQAPVYV
Protein: Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain] (Q02020)
Organism: Gallus gallus (Chicken)
Function: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots.
Subcellular location: Secreted {ECO:0000269|PubMed:10737772, ECO:0000269|PubMed:11601975}.
Interaction partners:
- Fibrinogen C-terminal domain-containing protein.
- Fibrinogen alpha chain
- Uncharacterized protein
- Antithrombin-III
- Plasminogen
- Plasminogen
- Uncharacterized protein.
- Alpha 2-HS glycoprotein.
- Coagulation factor XIII B chain.
- Serpin family D member 1
Sequence:
ASVEYDNEEDSPQIDARAHRPLDKRQEAAPTLRPVAPPISGTGYQPRPPKQDKQAMKKGPIIYPDAGGCKHPLDELGVLCPTGCELQTTLLKQEKTVKPVLRDLKDRVAKFSDTSTTMYQYVNMIDNKLVKTQKQRKDNDIILSEYNTEMELHYNYIKDNLDNNIPSSLRVLRAVIDSLHKKIQKLENAIATQTDYCRSPCVASCNIPVVSGRECEDIYRKGGETSEMYIIQPDPFTTPYRVYCDMETDNGGWTLIQNRQDGSVNFGRAWDEYKRGFGNIAKSGGKKYCDTPGEYWLGNDKISQLTKIGPTKVLIEMEDWNGDKVSALYGGFTIHNEGNKYQLSVSNYKGNAGNALMEGASQLYGENRTMTIHNGMYFSTYDRDNDGWLTTDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGTYSWDMAKHGTDDGIVWMNWKGSWYSMKKMSMKIKPYFPD
Protein: Nuclear factor erythroid 2-related factor 2a (Transcription factor nrf2) (Q8JIM1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MMEIEMSKMQPSQQDMDLIDILWRQDVDLGAGREVFDFSYRQKEVELRRRREQEEQELQERLQEQEKTLLAQLQLDEETGEFLPRSTPLTHTPEADGGGAGEITQNGAFAEQEADPMSFDECMQLLAETFPLTEPAESAPPCLNTSAPPSTDLMMPADVPAFTQNPLLPGSLDQAWMELLSLPELQQCLNMPMQETLDMNAFMKPSTEAPTQNYSQYLPGMDHLGSAQTEVCPPEFTNTYNRSFNTMVSPNMNQLSLNVPDVGAEFGPEEFNELFYPEMEVKVNNPPITSDGGNMVGDPPVNPIDLQSFSPGDFSSGKPDPIVEFQDSDSGLSLDASPHMSSPGKSITEDGSFGFSDSDSEEMEGSPGSMESDYNEIFPLVYLNDGSQTPLSEKSSTEKQEMKLKNPKMEPAEASGHSKPPFTKDKLKKRSEARLSRDEQRAKALQIPFTVDMIINLPVDDFNEMMSKHQLNEAQLALVRDIRRRGKNKVAAQNCRKRKLENIVGLEYELDSLKEEKERLMKEKSERSSNLKEMKQQLSTLYQEVFGMLRDENGKAFSPNEFSLQHTADGTVFLVPRLKKTLVKNI
Protein: E3 ubiquitin-protein ligase TRIM8b (Novel protein similar to vertebrate tripartite motif-containing 8 (TRIM8)) (Tripartite motif-containing 8b) (Q1MTE4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAENWKNCLEEELICPICLNVFSEPVQLPCKHNFCRMCINEAWSKDAGMVRCPECNNAYTQKPALEKNHKLSNIVEKFNALNVEKTPAVLHCILCRRGPPLQAQKVCLRCNAPCCHSHVQTHLQQPSSNAGHLLVDAEDVRAWSCPQHDEYRLYHCETEHVAVCQYCCFSRCATNHGHAVCDIEVRRNDIRQMLIKQQDRIEDRVQDIEEQLYKLESDKCLMEDKVQHLKEEVQLQYQKMQQLLEEDLGKTLEVLDKAHSKFCQENSAQALQLHQKQQEAKKLLSSIQMVFDKAEDIGFMKNTKSVKILMDRSQSYVGSTLSPYKVGSLNSKLFLSEISKREKNLCKMLEAPFSAPANFFQSIPAYLCEKRRHSMAFPEGSGSSRAGASYMDSSSSSGPASAKQPCLSLTQGSAPGEGQSSQQALGPCGSGQHVGSSSSASGSQPLPHSTSVFPHSHYPNGSSSQLPQYGARKILMCTVDNCYCSGVPSVSNHRSHPPYPRSSSFPWPVSSQEYSHAPLPSAPAMSQSLQSLSMRDWIDASQSHRHTDFYSLYGQSSTKHYVTS
Protein: Transcription factor TCP4 (Protein MATERNAL EFFECT EMBRYO ARREST 35) (Q8LPR5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Required during early steps of embryogenesis. Participates in ovule develpment. Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter. Activates YUC5 transcription by binding to the 5'-GTGGGCCA-3' motif found in its promoter. Through the activation of YUC5 transcription, integrates the auxin response to a brassinosteroid-dependent molecular circuit that promotes cell elongation in hypocotyls. Activates GIS transcription by binding to the 5'-TGGTCC-3' motif found in its promoter. Involved in the regulation of trichome branching through the activation of GIS transcription. Activates CO transcription by binding to the 5'-GGACCAC-3' motif found in its promoter. Involved in the regulation of photoperiodic flowering through the activation of CO transcription. Activates TCL1 and TCL2 transcription by binding to the 5'-TGGCCA-3' and 5'-GTGGACCA-3' motifS found in their respective promoters. Involved in the suppression of trichome initiaition through the activation of TCL1 and TCL2 transcription. Activates HAT2 transcription by binding to the 5'-TGGTCCAC-3' motif found in its promoter. Through the activation of HAT2 transcription, involved in the auxin-independent reprogramming of mitotic cells to exit division and acquire differentiation competence within the transition zone.
Subcellular location: Nucleus {ECO:0000269|PubMed:28628608}.
Interaction partners:
- Protein CUP-SHAPED COTYLEDON 2
- Protein JINGUBANG
- Squamosa promoter-binding-like protein 9
- Lipoxygenase 2, chloroplastic
- GRF1-interacting factor 1
- Protein CUP-SHAPED COTYLEDON 3
- Zinc finger AN1 and C2H2 domain-containing stress-associated protein 11
- Transcription factor TCP20
- Transcription factor TCP14
- Transcription factor TCP15
Sequence:
MSDDQFHHPPPPSSMRHRSTSDAADGGCGEIVEVQGGHIVRSTGRKDRHSKVCTAKGPRDRRVRLSAHTAIQFYDVQDRLGFDRPSKAVDWLIKKAKTSIDELAELPPWNPADAIRLAAANAKPRRTTAKTQISPSPPPPQQQQQQQQLQFGVGFNGGGAEHPSNNESSFLPPSMDSDSIADTIKSFFPVIGSSTEAPSNHNLMHNYHHQHPPDLLSRTNSQNQDLRLSLQSFPDGPPSLLHHQHHHHTSASASEPTLFYGQSNPLGFDTSSWEQQSSEFGRIQRLVAWNSGGGGGATDTGNGGGFLFAPPTPSTTSFQPVLGQSQQLYSQRGPLQSSYSPMIRAWFDPHHHHQSISTDDLNHHHHLPPPVHQSAIPGIGFASGEFSSGFRIPARFQGQEEEQHDGLTHKPSSASSISRH
Protein: LD13852p (Sin3A, isoform B) (Sin3A, isoform C) (Sin3A, isoform E) (Q5U0Y0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00810}.
Interaction partners:
Sequence:
MMKRTRVDEVQFGTRPVPQTSGGVGVGVVGVTGGGPTSGGGGTATVGVNTTGVTIGTVVPSAHNATISGIGSIHHRILTPQHGGAQTIAYLPSTTPTATNLKTTTSIVDSTTAGGPVGAGAQVAVGVGSAAGGGGVVVSTGSTGTQTLQYTTSYSVASIQAGGTLKANTADGANTVQIHVTGGGAANNPASAQTVSSSSQTGTIRQRTISGTQTVATAVGNLATISQQQPVQQSPLGKAQTPPSSVVANSIPVGGTTPPQGQSGNATPRLKVEDALSYLDQVKYQYADQPQIYNNFLDIMKEFKSHCIDTPGVIERVSTLFKGHTELIYGFNMFLPPGYKIEIHSDALGCSVPVVSMPSPPGAPTSTGTVHMLTGNSSMSGAGHIAIKTTNAATLTPAAGAGAAAAAAAVAQIQSAGAVNLMTHGGASLTQTTIHALQQATPPQSQSPGGGHVHVSVTNSTAANAVVPGQPGISVSAHNVPQNYSRDRERATITPTGQVAGAAANVNASASIVVGGPPTPNSLSELSPHGGAGGGPGAGAAQHNLHHIQQAHQSILLGETGQQNQPVEFNHAITYVNKIKNRFQNQPAKYKKFLEILHDYQREQKVMKEGSLNQGKMLTEQEVYTQVAKLFGQDEDLLREFGQFLPDATNHQSGQYMSKSASVHNDHGKRPTATLSGGAHITMSSASPAPSGSPLHLGATTLPQIDKSAHAAAIGNLSAVNTSVSIKTYNNNQQQQNHVIGSGLNATRNDILFEKDYHAGLQQQAHQRGAGVGGHHHLAGTAAGANIGRPGVGASVMVSYDKEHRNNHHVQKYVGHAPNQNLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHNSGSATRRPGDDSLVGHYASGAPPAKRPKPYCRDVSFSEASSKCTISDAAFFDKVRKALRSPEVYDNFLRCLTLFNQEIVSKTELLGLVSPFLMKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTALCREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETLYDERHDQEDDAMEPFGPHLVLPYKDKTILDDAANLLIHHVKRQTGIQKQEKQKIKQIIRQFVPDLFFAPRQPLSDDERDDAFPFLVDDNTKMDVDSPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGIKKETDDSKATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTEGKPKDDPLSSHKEEGAGSTSSGVATSPRQAQDTAGAGVDVEIKLEHPADFSNPKLLPPHAHGQREDESYTLFFANNNWYLFLRLHAILCDRLHVMYERARLLAIEEERCRVNRRESTATALRLKPKPEIQVEDYYPTFLDMLKNVLDGNMDSNTFEDTMREMFGIYAYISFTLDKVVSNAVRQLQYCVTERAALDCVELFATEQRRGCTGGFCRDAHKTFDREMSYQRKAESILNEENCFKVYIYKIDCRVTIELLDSEPEEVDKPAALKAQKFSKYVERLANPALGGGGNTGRSDSALGNDSVVDGSDIKTEADEDTAELRYREGGIGGAGKARFLVRNKRRSKLLEEQVRQLFEHRRNRIEQHGTAASLEPISVDSAISSNSTTGGGGSGTNNNNNNNNNNNSWGGKRLERLGAPQVGLAEQYAFNDRDEISTNISNGRCFVTSKNLKLLKYDAVRRAKKSHCRVTQAKYAHFQTYVNKWLQQHVSEQQQQNCVDWLLGKTADQINASGWGSASKTKTVQQKDTSKTPYRIYNRYRVVQSAVSGGLMSATAPTPDGSVPAVNSAPSGSVSTVNNVQGSAAVSSTSHSMCNSSILSADSTTNTNASAQQQQHCNSAAAATTPNAEALQQVRPMES
Protein: Nuclear receptor subfamily 2 group F member 2 (H3BTC2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLR
Protein: Syntaxin-7 (O15400)
Organism: Homo sapiens (Human)
Function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
Subcellular location: Early endosome membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Interaction partners:
- Syntaxin-8
- Vesicle transport through interaction with t-SNAREs homolog 1B
- Vesicle-associated membrane protein 7
- Vesicle-associated membrane protein 8
- Synaptosomal-associated protein 29
- Synaptobrevin homolog YKT6
- Syntaxin-6
- Vesicle transport through interaction with t-SNAREs homolog 1A
- Vesicle-associated membrane protein 4
- Synaptosomal-associated protein 23
Sequence:
MSYTPGVGGDPAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLIIWGLNH
Protein: GPN-loop GTPase 3 (EC 3.6.5.-) (Q06543)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Small GTPase required for proper nuclear localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. Promotes sister chromatid separation during anaphase.
Interaction partners:
- GPN-loop GTPase 1
- RNA polymerase II nuclear localization protein IWR1
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerases I and III subunit RPAC1
- GPN-loop GTPase 2
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB4
- RNA polymerase II subunit B1 CTD phosphatase RTR2
Sequence:
MSRVGVMVLGPAGAGKSTFCNSIISHMQTVGRRAHIVNLDPAAEATKYEFTIDIRDLISLDDVMEEMDLGPNGALIYCFEYLLKNLDWLDEEIGDFNDEYLIFDCPGQIELYTHIPVLPNIVRHLTQQLNFNLCATYLLEAPFVIDSSKFFSGALSAMSAMILLELPHINVLSKLDLIKGDINKKKLKRFLNPDAMLLMETEGMNQASNPKFLRLNQCIANLVDDFGMVQFLPLESNNPDSIETILSYVDDITQWAEGQEQKEPNDQIDVEE
Protein: DNA-directed RNA polymerase V subunit 5C (Q9M1H8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase V involved in RNA-directed DNA methylation-dependent (RdDM) silencing of endogenous repeated sequences, including transposable elements.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA-directed RNA polymerases II, IV and V subunit 11
- DNA-directed RNA polymerases II, IV and V subunit 8B
- DNA-directed RNA polymerases II, IV and V subunit 9B
- DNA-directed RNA polymerases II, IV and V subunit 9A
- DNA-directed RNA polymerases IV and V subunit 3B
- DNA-directed RNA polymerases II, IV and V subunit 3
- DNA-directed RNA polymerase V subunit 7
- DNA-directed RNA polymerases II, IV and V subunit 10
- DNA-directed RNA polymerases II, IV and V subunit 6A
- DNA-directed RNA polymerases II and V subunit 6B
Sequence:
MEETMAEEGCCENVESTFDDGTNCISKTEDTGGIESKRFYLARTTAFEMLRDRGYEVNEAELSLTLSEFRSVFGEKPELERLRICVPLRSDPKKKILVVFMGTEPITVKSVRALHIQISNNVGLHAMILVLQSKMNHFAQKALTTFPFTVETFPIEDLLVNITKHIQQPKIEILNKEEKEQLLRKHALEDKQLPYLQEKDSFVRYYGLKKKQVVKITYSKEPVGDFVTYRCII
Protein: MORF4 family associated protein 1 like 2 (MORF4 family-associated protein 1-like protein UPP) (Unnamed protein product) (UPP) (B2RBV5)
Organism: Homo sapiens (Human)
Function: May play a role in cell proliferation.
Interaction partners:
Sequence:
MRPVDADEAREPREEPGSPLSPAPRAGRENLASLERERARAHWRARRKLLEIQSLLDAIKSEVEAEERGARAPAPRPRAEAEERVARLCAEAERKAAEAARMGRRIVELHQRIAGCECC
Protein: Sushi domain containing 2, isoform CRA_a (Testicular tissue protein Li 190) (A0A140VJW3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKPALLPWALLLLATALGPGPGPTADAQESCSMRCGALDGPCSCHPTCSGLGTCCLDFRDFCLEILPYSGSMMGGKDFVVRHFKMSSPTDASVICRFKDSIQTLGHVDSSGQVHCVSPLLYESGRIPFTVSLDNGHSFPRAGTWLAVHPNKVSMMEKSELVNETRWQYYGTANTSGNLSLTWHVKSLPTQTITIELWGYEETGMPYSQEWTAKWSYLYPLATHIPNSGSFTFTPKPAPPSYQRWRVGALRIIDSKNYAGQKDVQALWTNDHALAWHLSDDFREDPVAWARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGSGQQCCYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPDCPRYMQRRPSNDCRNYRPPRLASAFGDPHFVTFDGTNFTFNGRGEYVLLEAALTDLRVQARAQPGTMSNGTETRGTGLTAVAVQEGNSDVVEVRLANRTGGLEVLLNQEVLSFTEQSWMDLKGMFLSVAAGDRVSIMLASGAGLEVSVQGPFLSVSVLLPEKFLTHTHGLLGTLNNDPTDDFTLHSGRVLPPGTSPQELFLFGANWTVHNASSLLTYDSWFLVHNFLYQPKHDPTFEPLFPSETTLNPSLAQEAAKLCGDDHFCNFDVAATGSLSTGTATRVAHQLHQRRMQSLQPVVSCGWLAPPPNGQKEGNRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKCQPGRSYAVLLGIIFGGLAVVAAVALVYVLLRRRKGNTHVWGAQP
Protein: DNA polymerase alpha subunit B (Q6P0S9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR018300}.
Interaction partners:
Sequence:
MASVTAEDIKSELDTFNIAFNNDTIDKMLEQCFCHRLTGEEIVFEWFAFSSTRKQLPLTLENLDQFEQEVLNKKKKPKSTSKGSQINKTRDINSIQELIRAEEEEENMLDSYSTPAKGSQKRALTTPEHPQSKRGVARLASPSLMLSPASFSPSATPSQKYGMRGGRGEVVSTFGAVQGPRWMGKGQTAVSVEMLDGGENSLISSYKYMFQRLRDVRDVLTGKIEELGEELRTNFNIEEFAPVSLPVQDSITVLGQVCCDSNGKLNAQSVLLEAGQEQGGRQVPVDLSELKEFSLFPGQVVVMEGMNPSGEKLVATKLYEGIPLPFYCPSEVKQEMDEVCEPVMVMIACGPYTPSESLTYDPLLDLITIINKDRPDVCILFGPFVDSKHEQIEKNQVTETFETIFKRCMDSIVEGTKGTACKLVFVPSQRDVHHHYIYPQPPFNLTISKEDTARVTLAPDPCTLLIGNVTFGLTSTDILFHMGAEEISSGTGTERFSRIMKHMLTQRSYYPLYPPAEEVNMDYDKFQQFSQMSLTPDILLAPSELRYFIKDVIGCVCVNPGRLTKGQIGGTYGRLLIQPNPAVVEGKRVSPCIAGQVVKI
Protein: Scm like with four mbt domains 2 (A0A669KBL2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MESTLSASNMQDPSSSPLEKCLGSANGNGDLDSEGSSLEETGFNWGEYLEETGASAAPHTSFKHVEISIQSNFQPGMKLEVANKNNPDTYWVATIITTCGQLLLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKVLMPPDAIKEKYTDWTEFLIRDLTGSRTAPANLLEGPLRGKGPIDLITVGSLIELQDSQNPFQYWIVSVIENVGGRLRLRYVGLEDTESYDQWLFYLDYRLRPVGWCQENKYRMDPPSEIYPLKMASEWKCTLEKSLIDAAKFPLPMEVFKDHADLRSHFFTVGMKLETVNMCEPFYISPASVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNGVSLTPPKGYSGQDFDWADYHKQHGAQEAPPFCFRNTSFSRGFTKNMKLEAVNPRNPGELCVASVVSVKGRLMWLHLEGLQTPVPEVIVDVESMDIFPVGWCEANSYPLTAPHKTVSQKKRKIAVVQPEKQLPPTVPVKKIPHDLCLFPHLDTTGTVNGKYCCPQLFINHRCFSGPYLNKGRIAELPQSVGPGKCVLVLKEVLSMIINAAYKPGRVLRELQLVEDPHWNFQEETLKAKYRGKTYRAVVKIVRTSDQVANFCRRVCAKLECCPNLFSPVLISENCPENCSIHTKTKYTYYYGKRKKISKPPIGESNPDSGHPKPARRRKRRKSIFVQKKRRSSAVDFTAGSGEESEEEDADAMDDDTASEETGSELRDDQTDTSSAEVPSARPRRAVTLRSGSEPVRRPPPERTRRGRGAPAASSAEEGEKCPPTKPEGTEDTKQEEEERLVLESNPLEWTVTDVVRFIKLTDCAPLAKIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVAFYAQYAN