wanglab/gogpt-training-data huggingface dataset:
Protein: Probable acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (Q46939)
Organism: Escherichia coli (strain K12)
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Fatty acid oxidation complex subunit alpha
- Fatty acid oxidation complex subunit alpha
- 3-hydroxyadipyl-CoA dehydrogenase
- Acyl-coenzyme A dehydrogenase
- Phosphate acetyltransferase
- 3-ketoacyl-CoA thiolase FadI
- Probable pyruvate-flavodoxin oxidoreductase
- Acetaldehyde dehydrogenase
- Acetyl-coenzyme A synthetase
- Bifunctional aldehyde-alcohol dehydrogenase AdhE
Sequence:
MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVTAENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQPRTDASAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCLERVGWQLAEVDLIEANEAFAAQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERDE
Protein: Uncharacterized protein (Q38BP1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Ubiquitin-like domain-containing protein
- Manganese/iron superoxide dismutase C-terminal domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Ribosomal protein S9
Sequence:
MRLGDYDSTHQILRSYHFTLELRLYFPLLPLCLFRSRYFVVAQSGNCTRSRNKEKPLVPPCSLFFLSICAMSFRYTNNLIGALKHRLLLESSYREIASRKFIGNCRGVEVVCSGYGTVLAVQLTDKAVWEPFYRKGGRPTVSGGGDVSGDAETGTQGSATTTGATGSLDLDKLAESIKTALWDATRKIRSAKEAALHRSLSHNTRMRASADLKHWYEEDANTLRPLAFEALKHEAATPWMQLVQHGKKEEAAALLKEFEQKGDAAEATPTRVKDDRVKGTRTELSNREQPPLASTLKAEDSNPATIPIGSVHPLFTPALVQIEEAGSGSVSNEAVCRAQLWELSRDEQLFWERVELIRKGQVASIGSSHKRGYADEAAFAKDDTEEKVQLRFTQ
Protein: G protein-regulated inducer of neurite outgrowth 2 (GRIN2) (O60269)
Organism: Homo sapiens (Human)
Function: May be involved in neurite outgrowth.
Interaction partners:
- Hydrocephalus-inducing protein homolog
- SLIT-ROBO Rho GTPase-activating protein 2
- SLIT-ROBO Rho GTPase-activating protein 3
- NBPF family member NBPF1
- D
- UDP-glucuronosyltransferase 2B17
- Puromycin-sensitive aminopeptidase
- General transcription factor II-I
- Guanine nucleotide-binding protein G
- Glutamate receptor ionotropic, NMDA 1
Sequence:
MSSSRPEPGPWAPLSPRLQPLSQSSSSLLGEGREQRPELRKTASSTVWQAQLGEASTRPQAPEEEGNPPESMKPARASGPKARPSAGGHWWSSTVGNVSTMGGSDLCRLRAPSAAAMQRSHSDLVRSTQMRGHSGARKASLSCSALGSSPVHRAQLQPGGTSGQGGQAPAGLERDLAPEDETSNSAWMLGASQLSVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREVRAGGCCHALPATGILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLEEVPSPVRDVRWDAEGMTWEVYGAAVDLEVLGVAIQKHLEMQFEQLQRAPASEDSLSVEGRRGPLRAVMQSLRRPSCCGCSGAAPE
Protein: Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (AD56) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin) (O88839)
Organism: Mus musculus (Mouse)
Function: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration (By similarity). Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain. Interactions with egg membrane could be mediated via binding between the disintegrin-like domain to one or more integrin receptors on the egg.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:18390692}; Single-pass type I membrane protein {ECO:0000269|PubMed:18390692}. Cell junction, adherens junction {ECO:0000250}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:18390692}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:18390692}. Note=The majority of the protein is localized in a perinuclear compartment which may correspond to the trans-Golgi network or the late endosome. The pro-protein is the major detectable form on the cell surface, whereas the majority of the protein in the cell is processed.
Interaction partners:
- Sorting nexin-9
- Cadherin-1
- SH3 and PX domain-containing protein 2A
- Proto-oncogene tyrosine-protein kinase Src
- SH3 and PX domain-containing protein 2B
Sequence:
MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRARLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKQASVVSFPVPPSRPLPPNPVPKKLQAALADRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPGDGSLPLVVPSRPAPPPPAASSLYL
Protein: E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (F1QB30)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:25064675}; Multi-pass membrane protein {ECO:0000255}. Note=Palmitoylation promotes localization to the peripheral endoplasmic reticulum. {ECO:0000250|UniProtKB:Q9UKV5}.
Interaction partners:
- Derlin
- E3 ubiquitin-protein ligase MARCHF6
- Derlin
- UBX domain-containing protein 1
- Ubiquitin-conjugating enzyme E2G 2
- Peptide-N
- Derlin
- UBA domain-containing 2.
- UV excision repair protein RAD23
- Fas-associated factor family member 2.
Sequence:
MPLLFLERFPWPSLQTYTALSALLLAGTVLSAYSTVRDSEFSSALSEGPQNEELKLENLGNVATGVLLHLITDSLFVWVMVNTACCILMLIGKVIQCIVFGPLRVSEKQHLKDKFWNFIFYKFIFIFGVLNVQRVEEVVLWCLWFSMLIFLHLMVQLCKDRFEYLSFSPTTPMSSHVRVLALLVSVLSCCGGLAVLCALAGHIHGMHTVAFMAAECLLVTVRTGHVIIRYSIHLWDLNHEGTWENKSSYIYYTDFIMELAILSLDLMHHIHMLLFGNIWLSMASLVIFMQLRHLFHEVQRRIRRHKNYLRVIDNMESRFAVATPEELAANNDDCAICWDSMTTARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIHEGRREREEGQREPLEDNMAAAGAADARAHINQHNHFFHFDGSRIASWLPSFSVEVMHTTNILGIAQANNSQLNGMAHQIQEMFPQVPYHLILQDLQLTRSVEVTTDNILEGRIQVPFPTQSTDRTPIQMNAASEDGAGASSGSEVAAPEAEDFEVRGSRFSKSADERQRMLMQRKEELLLRARRRYLHKKPEDGDAYSVLGADNDDSVPSIEDEDSDSVTLRRRRLAAAAERRILRQEPSPF
Protein: Candida glabrata strain CBS138 chromosome M complete sequence (Q6FJP9)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
Sequence:
MDFTSQARRIIKFAEKALQDETLDSDTVQRAIIERNLRIEFRRQNIVSNALKDCHYHQITDEELQSNLTNYPFMASIQARVAWRSILSSPTDPDKDYHNQTSTSINRKRSIYNSGHIPNKRLRNEKDRVDKLNQMVRDIENNTKVVETLLNESDITTSVDRPAINVHPFVEDEAPPPTITMDDLEIVSNATKNISNTNTVEKPYVSVSSNSRNEYETRHLKYDSTISRFGKIDHRRHSKENILIRNDNETHTIRRNSKSNKNPKSIRKMRAVAKKYHLEE
Protein: Hepatitis A virus cellular receptor 1 homolog (HAVcr-1) (Kidney injury molecule 1) (KIM-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (T-cell immunoglobulin mucin receptor 1) (TIM-1) (CD antigen CD365) (Q5QNS5)
Organism: Mus musculus (Mouse)
Function: Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Regulates also expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as regulator of T-cell proliferation. May play a role in kidney injury and repair (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q96D42}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Neutrophil gelatinase-associated lipocalin
- Cystatin-C
- Fatty acid-binding protein, liver
Sequence:
MNQIQVFISGLILLLPGAVDSYVEVKGVVGHPVTLPCTYSTYRGITTTCWGRGQCPSSACQNTLIWTNGHRVTYQKSSRYNLKGHISEGDVSLTIENSVESDSGLYCCRVEIPGWFNDQKVTFSLQVKPEIPTRPPTRPTTTRPTATGRPTTISTRSTHVPTSIRVSTSTPPTSTHTWTHKPEPTTFCPHETTAEVTGIPSHTPTDWNGTVTSSGDTWSNHTEAIPPGKPQKNPTKGFYVGICIAALLLLLLVSTVAITRYILMKRKSASLSVVAFRVSKIEALQNAAVVHSRAEDNIYIVEDRP
Protein: Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial (EC 1.6.5.9) (O43090)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the oxidation of NADH.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Probable mitochondrial-processing peptidase subunit beta
- Bax inhibitor 1
- GID complex subunit 9
- Uncharacterized dipeptidase C965.12
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
- 4,5-DOPA dioxygenase extradiol-like protein
Sequence:
MSVSKARLQSVVRLSRTVPYSKTMVRSFHVSCAVKNSGNVPTPRNKSFFSRALEMAEVTSSLSMLGAVALFQSLRRLNNSSPKGKSGVPKKNIVVLGSGWGAVAAIKNLDPSLYNITLVSPRDHFLFTPMLPSCTVGTLRLPSITEPIVALFKGKIDPSNIHQAECTAIDTSAKKVTIRGTTEANEGKEAVIPYDTLVFAIGAGNQTFGIQGVRDHGCFLKEAGDAKKVFNRIFEILEQVRFNKDLSPEERARLLHITVVGGGPTGMEFAAEMQDFIDNDVKDMFPELQKDIHVTLIEAAPGVLPMFTKSLITYTENLFKNLNIKIMTKTVVKDVNEKNLIVQKTNPDGSKAMQEIPYGMLVWAAGITARPLTRTLMSSIPEQSGARKGLIVDEFFRVKGVPEMYAVGDCAFSGLPATAQVANQQGAWLAKNLNVEGKKFALHERIQALEKQLGEKEAPSQVAGLKQQVEQLKLEPFKYHHQGALAYVGDEKAIADLKLPFMKKMLPLQGIVGHTFWRLAYLNELISARSQFMVLIDWLKTRLFGRYDAKV
Protein: Small ribosomal subunit protein mS40 (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) (28S ribosomal protein S18b, mitochondrial) (MRP-S18-b) (Mrps18-b) (S18mt-b) (P82918)
Organism: Bos taurus (Bovine)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11279123, ECO:0000269|PubMed:24799711}.
Interaction partners:
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein mS22
- Small ribosomal subunit protein mS27
- Small ribosomal subunit protein bS1m
- Small ribosomal subunit protein mS26
- Small ribosomal subunit protein mS34
- Small ribosomal subunit protein mS31
- Small ribosomal subunit protein mS33
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS5m
Sequence:
MAASVLNVLLRRLPYFSPFRGAYGVQVPLQTLCTKAPPEDDSLPPIPVSPYEDEPWKYLDSEEYHNRNGSRPVWADYRRNHKGGIPPQRTRKMCIRGNKVAGNPCPICRDQKLHVDFRNVKLLKQFVCAHTGIIFHAPYTGVCMKQHKKLTQAIQKARDHGLLSYHIPQVEPRDLDFSTSHGAVSATPPAPTLVSGDPWYPWYSWKQPPERELSRLRRLYQGHLREESGPPPESMPKVPLTAPNEATSTEQAGPQSAL
Protein: Phosphomannomutase (EC 5.4.2.8) (Q6FLW9)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU361118}.
Interaction partners:
- Mannose-6-phosphate isomerase
- Mannose-1-phosphate guanyltransferase 1
- Mannose-1-phosphate guanyltransferase 2
- Phosphotransferase
- Phosphotransferase
- Phosphotransferase
- Phosphotransferase
- Phosphotransferase
- Glucose-6-phosphate isomerase
- 6,7-dimethyl-8-ribityllumazine synthase
Sequence:
MSTPQEFAYKERPDVLVLFDVDGTLTPARLTVSDKVRDTLVKLRKKVCIGFVGGSDLSKQLEQLGPNVLNEFDYAFSENGLTAYRMGKQLASQSFINWIGEEKYNKLAKFILGYLANIDLPKRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHNIRAKFVEALKKEFPDYGLTYSIGGQISFDVFPTGWDKTYCLQHVEKDGFKEIHFFGDKTQVGGNDYEIFVDPRTIGHSVQTPDDTVKILNEIFNL
Protein: Claudin-11 (Oligodendrocyte-specific protein) (O75508)
Organism: Homo sapiens (Human)
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Subcellular location: Cell junction, tight junction. Cell membrane {ECO:0000269|PubMed:20375010}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Tight junction protein 1
- Occludin
- Tight junction protein ZO-3
- Peripheral myelin protein 22
- Claudin-23
- Claudin-3
- Claudin-2
- Claudin-25
- Claudin-12
- Claudin-10
Sequence:
MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQLAGVLLILLALCALVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVILCCAGDAQAFGENRFYYTAGSSSPTHAKSAHV
Protein: Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) (Q15262)
Organism: Homo sapiens (Human)
Function: Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.
Subcellular location: Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Epidermal growth factor receptor
- R-spondin-2
- Mitogen-activated protein kinase kinase kinase 21
- Serine/threonine-protein kinase PDIK1L
- Retinal guanylyl cyclase 2
- R-spondin-3
- Catenin beta-1
Sequence:
MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRGHNESKADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPTLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAMECYQVPVTYQNAMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLVVILIVKKSKLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHNFSPRYENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS
Protein: Sorting nexin-2 (D6RC15)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPKPTEVVLDDDREDLFAATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSE
Protein: Receptor expression-enhancing protein 4 (Q6AZM3)
Organism: Xenopus laevis (African clawed frog)
Function: Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes (By similarity). May play a role in the maintenance of both the nervous system and the musculature.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MVSWIISRAVVLVFGLLYPAYASYKAVKTKNVRDYVRWMMYWIVFALFMTVETFTDIFIAWFPFYYEIKMAFVVWLLSPYTRGASLLYRKCIHPTLSLKEKEIDSYIIQAKERSYESFVNIGRKGLNIAASAAVQAATKGQGALVGRLRSFSMQDLRALPDDTPIHYTDALYPDEPQLHRRPMGFPTTSQADSDSMDERWSDSEIAETRTAARTRGGMPSKSLQRSQSLRVSKKKGLSREVSTKTTKPRAKKKPAQSEPEN
Protein: ERCC excision repair 4, endonuclease catalytic subunit (D3ZT95)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- DNA excision repair protein ERCC-1
- DNA repair protein complementing XP-A cells homolog
- DNA excision repair protein ERCC-5
- Structure-specific endonuclease subunit SLX4
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- Structure-specific endonuclease subunit MUS81
- Fanconi anemia core complex-associated protein 24
- DNA repair protein RAD52 homolog
- DNA mismatch repair protein Msh2
- Structure-specific endonuclease subunit SLX1
Sequence:
MERGLPGERQSMAPLLEYERQQVLELLDSDGLVVCARGLGADRLLYHFLRLHCHPACLVLVLNTQPAEEEYFINQLKIEGVEHLPRRVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVKKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPAMLAIQTAILDVLNACLKELKYHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKVFGQNSGWLFLDASTSMFVNARARVYRVPDVKLSKKTKTSEKMAGPEEQETKKELVLESNPKWEALTEVLKEIETENKESEALGGPGQVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDGKAEEVWVNFRKGDGPKRTMKSDKRPKDAQNKERASTKRGALKRKKKRELTLTQVLGTAEEPPEEGAVEEDLHKQTGSSPEVCGGEIQHESFDLNVSSDAAYGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPGKPLRVYFFVYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLARGTAAMDTPTDTRKAGGQERNGTQPSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFVQEMSSSDVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSETLPESDRYNPGPQDFVLKMPGVNAKNCRSLMNQVQNIAELATLSLERLTGILGHSGNAKQLHDFLHTAYADLVSKGRVRK
Protein: mRNA export factor GLE1 (GLE1-like protein) (Nucleoporin GLE1) (Protein EMBRYO DEFECTIVE 1745) (Protein GLE1) (AtGLE1) (Q0WPZ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for seed viability.
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:21189294}. Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
Interaction partners:
- DEAD-box ATP-dependent RNA helicase 38
- Protein RAE1
- Nuclear pore complex protein NUP155
- F7H2.18 protein
- Nuclear pore complex protein NUP107
- Nuclear pore complex protein NUP54
- Protein SEH1
- Nuclear pore complex protein NUP205
- Nuclear pore complex protein NUP98A
- Nuclear pore complex protein NUP85
Sequence:
MGIVLEPPCPKSVDGISIDPEPNWNFESLVAEIASVEKKLNGFSMYPQPITNTTLRMGRRGGGFVMHVSEDEMESDEGEESDDEEEEEDHSQICTAGKRFACDELYLSDESDEEFDHEPEYMMNKLGLAESALYEVINDHQTEIKDDIRNQVSVVETEIMNEIETSLSAIARVEKYSETRKEVERKLDLQYQRKVAEALDTHLTAVQREHKIKSQIEERKIRSEEAQEEARRKERAHQEEKIRQEKARAEAQMLAKIRAEEEKKEVERKAAREVAEKEVADRKAAEQKLAEQKAVIESVTGSSATSNAQAGGNSIRAAESALILENHRLKKLEELETTNQSLKSRSNENFSSFEKHIGRVIRQISGTKDSVSGKINDIVKIFKDPRCPVSISIAAFAKKMVTTKEKPNPFACSYVIVYINSQFPQVMDILLAEFHKACIYTVPKHIVNSQSAWDSDAYERLDSIMRLYGALVQTDIRVGNATNVHGIEHGWAWLARFLNKIPANRATATALNSFLQTAGFGLHQRYKSQFLKVVNVVREHFLQKLRAKKDTSDLLVIIAEITAYLDDRMYLKEPEGRAMKTTSTLSSELTAELNQPNYNQNYQRNDYRNYY
Protein: Obg-like ATPase 1 (P38219)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03167, ECO:0000269|PubMed:10684247, ECO:0000269|PubMed:14562095}.
Interaction partners:
- Translation machinery-associated protein 20
- Elongation factor 1-gamma 2
- Phenylalanine--tRNA ligase beta subunit
- Peptidyl-tRNA hydrolase
Sequence:
MPPKKQVEEKKVLLGRPGNNLKAGIVGLANVGKSTFFQAITRCPLGNPANYPFATIDPEEARVIVPSPRFDKLCEIYKKTASEVPAHLTVYDIAGLTKGASAGEGLGNAFLSHIRSVDSIYQVVRCFDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFAQKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLESGQRVANHSWTSKEVEIINSMFLLTAKPCIYLINLSERDYIRKKNKHLLRIKEWVDKYSPGDLIIPFSVSLEERLSHMSPEDAEEELKKLQTISALPKIITTMRQKLDLISFFTCGPDEVREWTIRRGTKAPQAAGVIHNDLMNTFILAQVMKCEDVFEYKDDSAIKAAGKLMQKGKDYVVEDGDIIYFRAGAGKN
Protein: Brevinin-1AVa (P86159)
Organism: Rana arvalis (Moor frog)
Function: Antimicrobial peptide.
Subcellular location: Secreted {ECO:0000269|PubMed:18280749, ECO:0000269|PubMed:19308951, ECO:0000269|PubMed:35820801}.
Interaction partners:
Sequence:
FLPLLAASFACTVTKKC
Protein: Zinc finger protein 550 (Q7Z398)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MAETKDAAQMLVTFKDVAVTFTREEWRQLDLAQRTLYREVMLETCGLLVSLGHRVPKPELVHLLEHGQELWIVKRGLSHATCAGDRAQVHTREPTTYPPVLSERAFLRGSLTLESSTSSDSRLGRARDEEGLLEMQKGKVTPETDLHKETHLGKVSLEGEGLGTDDGLHSRALQEWLSADVLHECDSQQPGKDALIHAGTNPYKCKQCGKGFNRKWYLVRHQRVHTGMKPYECNACGKAFSQSSTLIRHYLIHTGEKPYKCLECGKAFKRRSYLMQHHPIHTGEKPYECSQCRKAFTHRSTFIRHNRTHTGEKPFECKECEKAFSNRAHLIQHYIIHTGEKPYDCMACGKAFRCSSELIQHQRIHTGEKPYECTQCGKAFHRSTYLIQHSVIHTGEMPYKCIECGKAFKRRSHLLQHQRVHT
Protein: Gap junction alpha-10 protein (Connexin-57) (Cx57) (Q9WUS4)
Organism: Mus musculus (Mouse)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17681699}; Multi-pass membrane protein {ECO:0000269|PubMed:17681699}. Cell junction, gap junction {ECO:0000269|PubMed:17681699}.
Interaction partners:
Sequence:
MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLGVAAEDVWDDEQSAFACNTQQPGCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRDFEKQRQKKKLYLRAQMENPELDLEEQQRVDKELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMHPIYKCTQAPCPNSVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRALDGKSSSGNTENETGPPFHSTNYSGTQQCMICSSLPERISLLQANNKQQVIRVNIPRSKSMWQIPHPRQLEVDVSCGKRDWAEKIESCAQLHVHSPCPHDRSARIQHPGQQPCHSVFGPKNAMSQSWFGTMTASQHRPSSALETWERSQGPEASGRSLTDRQSHFQGSDGSARESGVWTDRLGPGSRKASFLSRLMSEKGQRHSDSGSSRSLNSSCLDFSHGENSPSPLPSATGHRASMVSKSSHVDSPPHSSFIIHETYVYVY
Protein: Integrin beta (Q3YAA1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU000633}; Single-pass type I membrane protein {ECO:0000256|RuleBase:RU000633}. Cell projection, invadopodium membrane {ECO:0000256|ARBA:ARBA00004297}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004297}. Cell projection, lamellipodium {ECO:0000256|ARBA:ARBA00004510}. Cell projection, ruffle membrane {ECO:0000256|ARBA:ARBA00004199}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004199}. Melanosome {ECO:0000256|ARBA:ARBA00004223}.
Interaction partners:
Sequence:
MDLKLLFISALLGIISCSRAQQEGNECIKANALSCGECIQVGDKCGWCTDAEFLKQGEPTSARCDELESLKKRGCAEAKIENPHGSQRILKNTPVTNRKKGAEKLRPEDITQIQPQKLSLQLRSGEPQNIKLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKNLGTSLMKEMSKITSDFRIGFGSFVEKTVMPYISTTPAKLLNPCTGDQNCTSPFSYKNVLKLTSNGQRFNSLVGQQQISGNLDSPEGGFDAIMQVAVCGEHIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGRCHLENDMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVINLIVDAYNSLSSEVILENSKLPEGVTITYQSRCKNGVVNEGESGRKCSNISIGDEVSFNINITAQGCPKQGKTETIKIKPLGFTEEVEITLSFICECECHKHAMKNSPLCHNGNGSFECGACRCNKGRVGRQCECRKDEVSTEDLDKNCRKDNGTDICSNNGECVCGTCECKKRENPEERYSGKYCECDNFNCDRSNNKLCGGHGRCECRVCVCDANYTGSACDCSLDTSTCLASNKQICNGRGICECGTCRCTDPKFQGPTCEICPTCPGVCTEHKECVQCRAFGTGEKKDTCKRDCSYFNLIEVEDRDKLPQPVQAFPLMHCKERDARDCWFYYTYAVNNNTEKEVHVVKTMECPPGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVINPKYEGK