wanglab/gogpt-training-data huggingface dataset:
Protein: Transcription factor LBX1 (Ladybird homeobox protein homolog 1) (P52955)
Organism: Mus musculus (Mouse)
Function: Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MTSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLLAAADKHAPGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEASGGGGGGGCGRAKSRPGSPALPPGAPQAPGGGPLQLSPASPLTDQRASSQDCSEDEEDEEIDVDD
Protein: Protein ripply1 (Q2WG77)
Organism: Mus musculus (Mouse)
Function: Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q2WG80}.
Interaction partners:
- Mesoderm posterior 2
Sequence:
MDPAASPAAAPPAAPAAAPAADPAADPAAALPGQALAQAPALAQINGQEGARNERAAYLWRPWLSSINDQPRQARSLVDWADNRATAAEAAKTDSDFHHPVRLYWPKSHSFDYLYSAGEILLNNFPVQATINLYEDSDSADNEEDKEEEEEEEEEEDDEEEEEDEDKDVNENEPEVCMGVSEATTHKATAHSPDPHSACPN
Protein: Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3) (P11802)
Organism: Homo sapiens (Human)
Function: Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18827403}. Nucleus {ECO:0000269|PubMed:18827403, ECO:0000269|PubMed:20399237, ECO:0000269|PubMed:9106657}. Nucleus membrane {ECO:0000269|PubMed:18827403}. Note=Cytoplasmic when non-complexed. Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G(1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G(1) to S phase. Also present in nucleoli and heterochromatin lumps. Colocalizes with RB1 after release into the nucleus. {ECO:0000269|PubMed:18827403}.
Interaction partners:
- Cyclin-L2
- Cyclin-dependent kinase 4 inhibitor D
- Retinoblastoma-associated protein
- G1/S-specific cyclin-D1
- Cyclin-dependent kinase inhibitor 2A
- Cyclin-A2
- Cyclin-dependent kinase inhibitor 1B
- G1/S-specific cyclin-D2
- G1/S-specific cyclin-D3
- Cyclin-dependent kinase inhibitor 1
Sequence:
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE
Protein: Major urinary protein 1 (MUP 1) (P11588)
Organism: Mus musculus (Mouse)
Function: Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.
Subcellular location: Secreted.
Interaction partners:
- Major urinary protein 17
- Major urinary protein 21
Sequence:
MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE
Protein: Circumsporozoite protein (CS) (PfCSP) [Cleaved into: Circumsporozoite protein C-terminus] (Q7K740)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P19597}; Lipid-anchor, GPI-anchor {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:P23093}. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites. {ECO:0000250|UniProtKB:P23093}.
Interaction partners:
- Small ribosomal subunit protein eS30
- Merozoite surface protein 1
- Liver stage antigen 1
- Apical membrane antigen 1
- Merozoite surface protein 2
- Thrombospondin-related anonymous protein
- 40S ribosomal protein S15A, putative
Sequence:
MMRKLAILSVSSFLFVEALFQEYQCYGSSSNTRVLNELNYDNAGTNLYNELEMNYYGKQENWYSLKKNSRSLGENDDGNNEDNEKLRKPKHKKLKQPADGNPDPNANPNVDPNANPNVDPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNKNNQGNGQGHNMPNDPNRNVDENANANSAVKNNNNEEPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKCSSVFNVVNSSIGLIMVLSFLFLN
Protein: Protein MIX23 (Caffeine-induced death protein 2) (O74982)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Uncharacterized membrane protein C61.05
- Bifunctional purine biosynthesis protein ade10
- Meiotic expression up-regulated protein 27
- Aspartic proteinase yapsin-1
- Terminal uridylyltransferase cid1
Sequence:
MNEEKRGLCMNIRYLKNVLRKARKIDDTIQLSLNSAKWEYPEGKVHETQEERCQNVKKKLFEGWLSRDQFLKECQTIVRSQLDQDRNTSKSPLKSQQQLPSSSTTQVSERLDPYAKEVQVQLSPPEEVQIVLQSELSVEQIIRDQTWEVLTNACPGMFKDWRDTYKD
Protein: Heterogeneous nuclear ribonucleoprotein M (hnRNP M) (Q9D0E1)
Organism: Mus musculus (Mouse)
Function: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Heterogeneous nuclear ribonucleoprotein U
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoproteins C1/C2
- Heterogeneous nuclear ribonucleoprotein A1
- Heterogeneous nuclear ribonucleoprotein A3
- RNA-binding motif protein, X chromosome
- Poly
- RNA binding motif protein, X-linked-like-1
- BUB3-interacting and GLEBS motif-containing protein ZNF207
- RNA binding motif protein, X-linked-like 2
Sequence:
MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPGPKGEERPTQNEKRKEKNIKRGGNRFEPYSNPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGIVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLSKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRISGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSSIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGASLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGAGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA
Protein: Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit) (Q64537)
Organism: Rattus norvegicus (Rat)
Function: Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity).
Subcellular location: Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon calcium binding (By similarity). Allows the formation of the homodimer and also appears to mediate the contact between the large catalytic subunit and small regulatory subunit for the formation of the heterodimer. {ECO:0000250}.
Interaction partners:
- Calpain-2 catalytic subunit
- Calpastatin
- Calpain-1 catalytic subunit
- Caspase-3
- Calpain-6
- Calpain-5
- Calpain-7
- Caspase-9
- Caspase-1
- GPI-anchor transamidase component PIGU
Sequence:
MFLVNSFLKGGGGGGGGGGLGGGLGNVLGGLISGAAGGGGGGGGGGGMGLGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRSHYSNIEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTMYS
Protein: Surface layer protein (O68840)
Organism: Geobacillus stearothermophilus ATCC 12980
Interaction partners:
Sequence:
MDKKKAVKLATASAVAASAFVAANPHASQAATDVATVVSQAKAQMKEAYYTYSHTVTETGQFPDIKDVYAAYNKAKQAYANAVAVVNKAGGAKKDAYLADLQAIYETYVFKANPKSGEARVATYIDAYNYATKLDKMRQELKAAVDAKDLKKAEELYHKISYELKTRTVILDRVYGQSTRELLRSTFKADAQALRDRLIYDITVAMKAREAQDAVKAGNLDKAKAALDQVNQYVSKVTDAFKAELQKAAQDAKAAYEAALTPKVESVSAIDSTSFKVTFTKPVDKATAIPKNFSITLKGTETKLYPKSVEVSESGLTATVTLYDTLVDGKTYTVVTSGLKDTAGKEFETSTNEFTYNKPVPASITFNFNKLPEDSAVDLTKYVTVKDAAGNVIKSGFELEFTSSEKLTQGKFINTTGKKSVIVNATVKGTNVTTGNVILAVEDEKAAEVSELKLTKDNKEVVTLYANGNAFDKDGNQISSGTLTLTAKFKDQYGNELTGKVAGTDYTFESLNPEVLVVAPDGSVTPIVPGTALVKVKYGEVTKTIPVTVKANPVLETIAVDSTGVSVAKGQKATFKVTLKDQYGNKFTGNVNVTSDKTETATVSVSNSGIGQSEYTVTVNGVAEGSTTITIKSGTKEVKVPVNVVAGGPVANYQIKVLDDGKIDKSATESPANNDVQLKVYAVDANGNIVGDITNDVTITSEATDTNGVIVNASKSTANGDTVYVITDNGSKKVGKETLTVKLGTVTLGTVDVEVIDTTLKATVVTKKADLIELDAADNGDALAKLLANLDIKDQNGNPMVDSAATPNTNEKLQALKSVLSGIVSSDTSVIGSVSNVDNLKDDASISGLAVKKAGTVTLTLVFNEDSKIAPIAITVKAPAATQDGVTVTGLDLVPGVTGVGKTKFTATDKIKSGHKLYYAVDDSAVPAPAVGTTRNSTKFANEITVGTTEVAANAGQIITVIEVDSSDRVVGYKTFTVEAADLSVAADKTGFTATVTPTGGNQVTTGKTLLAVSDLANGHKLYAAAAGSSAAAAPVKGIAYTDTTVRTTYGTEVTSGTVEVDAQDGQHISIIEVDENGKVVGYKDYTITGIQIGTKSAS
Protein: Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I) (P20839)
Organism: Homo sapiens (Human)
Function: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03156, ECO:0000269|PubMed:14766016}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03156, ECO:0000269|PubMed:14766016}.
Interaction partners:
- GMP synthase
- Inosine-5'-monophosphate dehydrogenase 2
- Adenylosuccinate synthetase isozyme 2
- Bifunctional purine biosynthesis protein ATIC
- Adenylosuccinate synthetase isozyme 1
- AMP deaminase 2
- AMP deaminase 3
- AMP deaminase 1
- Inosine triphosphate pyrophosphatase
- Hypoxanthine-guanine phosphoribosyltransferase
Sequence:
MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Protein: Avirulence protein ATR1 (Arabidopsis thaliana recognized protein 1) (M4B6G6)
Organism: Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent) (Peronospora arabidopsidis)
Function: Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying both defense protein RPP1 from several ecotypes including RPP1-NdA, RPP1-WsB, RPP1-EstA and RPP1-ZdrA.
Subcellular location: Secreted {ECO:0000269|PubMed:15894715}. Host cytoplasm {ECO:0000269|PubMed:15894715}.
Interaction partners:
Sequence:
MRVCYFVLVPSVALAVIATESSETSGTIVHVFPLRDVADHRNDALINRALRAQTALDDDEERWPFGPSAVEALIETIDRHGRVSLNDEAKMKKVVRTWKKLIERDDLIGEIGKHYFEAPGPLHDTYDEALATRLVTTYSDRGVARAILHTRPSDPLSKKAGQAHRLEEAVASLWKGRGYTSDNVVSSIATGHDVDFFAPTAFTFLVKCVESEDDANNAIFEYFGSNPSRYFSAVLHAMEKPDADSRVLESSKKWMFQCYAQKQFPTPVFERTLAAYQSEDYAIRGARNHYEKLSLSQIEELVEEYSRIYSV
Protein: Neogenin (P97798)
Organism: Mus musculus (Mouse)
Function: Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Netrin-1
- Hemojuvelin
- Repulsive guidance molecule A
- Netrin-3
- Repulsive guidance molecule B
- Bone morphogenetic protein receptor type-1A
- Netrin receptor UNC5B
- Focal adhesion kinase 1
- Transmembrane protease serine 6
- Bone morphogenetic protein receptor type-1B
Sequence:
MAAEREAGRLLCTSSSRRCCPPPPLLLLLPLLLLLGRPASGAAATKSGSPPQSAGASVRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKGTDKEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVVIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPLYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA
Protein: Fgl2 protein (Q5U3X5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
WLSSAVLAACRAAEKHNLTEGLEDASAQAACPARLEGSGRCEGSQCPFQLTLPTLTLQLPQQFGSMEEVLKEVRTLQEAVDSLKKSCQDCKLQADEHPDPGGNGAETAEDNRVQELESQVNKLSSELKNAKEEIQGLQGRLESLQLVNMNNIENYVDNKVANLTSVVNSLDSKCFKCPSQEHNQPNPVQHLIYKDCSDYYVLGKRSSGTYRVTPDHRNSSFEVYCDMETTGGGWTVLQARLDGSTNFTRGWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYAVYDQFYVANEFLKYRLHLGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQRYKGVRNGIFWGTWPGVSQAHPGGYKFSFKKAKMMIRPKSFKP
Protein: Myb family transcription factor PHL7 (Protein PHR1-LIKE 7) (Q9SJW0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
- Pectate lyase
- Probable pectate lyase 9
- Probable pectate lyase 7
- Probable pectate lyase 5
- Probable pectate lyase 19
- Probable pectate lyase 6
- Serine carboxypeptidase-like 35
Sequence:
MEADNGGPNSSHASKQRLRWTHELHERFVDAVAQLGGPDRATPKGVLRVMGVQGLTIYHVKSHLQKYRLAKYLPDSSSEGKKTDKKESGDMLSGLDGSSGMQITEALKLQMEVQKRLHEQLEVQRQLQLRIEAQGKYLKKIIEEQQRLSGVLGEPSAPVTGDSDPATPAPTSESPLQDKSGKDCGPDKSLSVDESLSSYREPLTPDSGCNIGSPDESTGEERLSKKPRLVRGAAGYTPDIVVGHPILESGLNTSYHQSDHVLAFDQPSTSLLGAEEQLDKVSGDNL
Protein: Gallinacin-9 (Gal-9) (Beta-defensin 9) (Gallinacin-6) (Gal-6) (Q6QLR1)
Organism: Gallus gallus (Chicken)
Function: Has bactericidal activity. Potent activity against C.jejuni, C.perfringens, S.aureus, C.albicans and S.cerevisiae. Less potent against S.typhimurium and E.coli.
Subcellular location: Secreted. Cytoplasmic granule {ECO:0000250}.
Interaction partners:
- Gallinacin-10
- Gallinacin-8
- Gallinacin-3
- Gallinacin-1
- Gallinacin-4
- Gallinacin-14
- Gallinacin-6
- Gallinacin-2
- Gallinacin-5
- Gallinacin-7
Sequence:
MRILFFLVAVLFFLFQAAPAYSQEDADTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
Protein: Magnesium protoporphyrin IX methyltransferase, chloroplastic (EC 2.1.1.11) (Q9SW18)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Converts Mg-protoporphyrin IX to Mg-protoporphyrin IX methylester using S-adenosyl-L-methionine as a cofactor. Involved in chloroplast-to-nucleus signaling by acting as a negative effector of nuclear photosynthetic gene expression.
Subcellular location: Plastid, chloroplast membrane {ECO:0000269|PubMed:11784318}; Peripheral membrane protein {ECO:0000269|PubMed:11784318}. Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:11784318}; Peripheral membrane protein {ECO:0000269|PubMed:11784318}.
Interaction partners:
- Magnesium-chelatase subunit ChlH, chloroplastic
- Magnesium-chelatase subunit ChlD, chloroplastic
- Magnesium-chelatase subunit ChlI-1, chloroplastic
- Magnesium-chelatase subunit ChlI-2, chloroplastic
- Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic
- Chlorophyll synthase, chloroplastic
- Porphobilinogen deaminase, chloroplastic
- Tetrapyrrole-binding protein, chloroplastic
- Geranylgeranyl diphosphate reductase, chloroplastic
- Glutamyl-tRNA reductase 1, chloroplastic
Sequence:
MPFAPSLLSSSSSVSQFLPRFPNATRFNVTPRSRAATVVAASVTDLAGVDSTTIAVLGGGSVAALAAMVSLTDPERRRKLQAEEVGGGDKEVVREYFNSTGFERWRKIYGETDEVNRVQKDIRLGHAKTVENTMLMLTEDRSLAGVTVCDAGCGTGLLSIPLAKEGAIVSASDISAAMVAEAEMKAKAQLPSENLPKFEVNDLESLTGKYDTVVCLDVLIHYPQNKADGMIAHLASLAEKRVILSFAPKTFYYDILKRIGELFPGPSKATRAYLHSEADVERALGKVGWKISKRGLTTTQFYFSRLIEAVPM
Protein: Probable lysine-specific demethylase SE14 (EC 1.14.11.-) (Protein PHOTOPERIOD SENSITIVITY 14) (Q10RP4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3. Involved in the control of flowering time. Has a suppressive effect on floral transition under long day conditions through the demethylation of H3K4me3 in the promoter region of the flower-promoting signal HD3B/RFT1.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537}.
Interaction partners:
- ATP synthase subunit b, chloroplastic
- ATP synthase subunit alpha, chloroplastic
- ATP synthase subunit alpha
- Polycomb group protein EMF2B
- Histone-lysine N-methyltransferase EZ1
- Histone-lysine N-methyltransferase CLF
- Os06g0275250 protein
- Polycomb group protein FIE1
- Polycomb group protein FIE1
- Polycomb group protein EMF2A
Sequence:
MPPQPPPAASASASAPDPAVPAWLRGLPRAPEYRPTESEFADPIAFLSRVEREAAAYGICKVIPPHPRPSRRFVFAHLNRSLVSSCDAPAPSPAAASDSSIPPSSSSPPPVSAAVFTTRHQELGNPRRGRPTPQVLKQVWQSGERYTLDQFESKSRAFSKTHLAGLHEPTALAVESLFWKASADRPIYIEYANDVPGSGFAAPVQLQRKKKQKRETAPMDEWEKSSGWRLSNSPWNLQAIARAPGSLTRFMPDDVPGVTSPMVYIGMLFSWFAWHVEDHDLHSLNFLHTGAPKTWYAVPGDRAVELEEVIRVHGYGGNTDRIASLAVLGEKTTLMSPEVLIDNGVPCCRLVQYPGEFVVTFPRAYHVGFSHGFNCGEAANFATPQWLKFAKEAAVRRAVMNYLPMLSHQQLLYLLAVSFISRNPRELLSGIRTSRLRDRKKEDRELLVKQEFLQDMISENELICSFLGKKSVDNVVLWEPDLLPSLTALHPCSSCSKAPEKKGEDGPRIGSTQSSSKDDSSSDGTACMTGTQSKGLSMDSKQAPEGEKLDTDDGDDLPFDLSIDSGSLTCVACGILGYPFMAILQPSRKALEEISLVDKERYKLSCEKEICSNVLPCSPNDGSSGCPLIANRSSSPVENANLSHQDVKPIRSDISLMGKEFNGTLGKHIGTSCSCSSENTIHPYGDTETPEKKIPSDCPGSELSKQSGRGDVNVPDVEGSEETISWNTGCAFARPRIFCLQHALEIEELLASKGGVHALIICHADYVKLKALAISIAEEIEFQFDYKDVALANASKSNLHLINISIDDEGYEEEGTDWTSRMGLNLKHSSKIRKETPESQEQPPLSFWGLFSKPSPISVVSNLKWLCRKARTPYKVIGYASSPDVVATPDKVKPAVTKTQIDTSGNAHENIGSEQTLQQDCVLQESNDVADMCKRPKVNDQDGHSLINIPIAVAEYPMMHQVCERPVSVSACDDPICSFDSQDSPTTVAVSAGKPTREQCGAESTELSTVKQFLDNGLIAEGGSMNFISNHEHLESDNATSVCKDEQLQVQQDQLAMVLCNNPNTELVAGELHGGAASSTLENEDSCGNTSYCSDTVLKNSEPDTDDQPETCDRSVVLVTPKSSCDQMISSSDRSCSLTLDCPVSTDAAFSSEKLSMAHDLMGSELQAVHNSKAEVVASLTDVKGAKLNSIHTTQLPHESPSSDFIISEGAQSASTTAIPRKNGTSMHTESNSIDILLGVLADESKVSSGKDEVGKASLTLMTLAGNDQSADDVTQDEVAEITDPSHGFCSSDIVSRSIGSSNRTNIICYARRKHKRKSGSEFNINSPQSLGSFVRSPCESLRPRTRPAIVEDMTNETKTAEASTANKRKKAKVEAFQCDIEFCDMTFETKAELRAHQRNICTDESCGKRFSSHKYLKRHQCVHRDERPFKCPWDGCPMTFKWLWAQTEHIRVHTGERPYKCSAPDCGQSFRYVSDYSRHRKKFNHY
Protein: Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin) (Q4QPP5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000256|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|HAMAP-Rule:MF_03023}. Note=Predominantly cytoplasmic. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with KATNB1. {ECO:0000256|HAMAP-Rule:MF_03023}.
Interaction partners:
- Katanin p80 WD40 repeat-containing subunit B1
Sequence:
MFNTSAQNWFGMGQTAVDPSGGVAQLLNNNSSLYNQQQQQAAAAQHSFMRQRSLTSSNPVLGRSNALATRPQSPPNVQVEYEVAVPFVPTYRHTPYHSLWDLHQCSSTPPTSLSHMARMMDSLILDSLSPFGFTKITATSRPSRNASLKKSSEGGHSSTAERHRPVNNLGSNAPGGLGIGGSVPLRSKQRLPTQVSAAEVAPQPRASQTAQMPFPSQQQDNRWVSSLRRRDPELQPTLPSINSNANSSSLSQSHHGSAGNVGLAGAGAPTPAASMGTMRLGRPARASAMTAALRKSRSVERLRARKLSTNTQLNLKHKPVKKNSLDENSNSDDQDATTSLEDNSHAQSLATSHNTPKCSPKTKAKHFSPLGYEVHLVDTLEKDILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASRGSDSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEAFRRRFEKRIYIPLPNEGTRSALLKLCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRLISGRTPDQIKQIRREEVDQPITLQDFQDARLRTKKSVSADDVARFEKWMEEYGSC
Protein: Heat shock transcription factor 4 (H0YAU2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XTCPLPGALLQDPYFIQSEEKMEASLPPNQTQALQHGLSLLPQTFSLRPGPAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEASPS