wanglab/gogpt-training-data huggingface dataset:
Protein: 1-phosphatidylinositol 4-kinase (EC 2.7.1.67) (Q9W4X4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTMTASDKYTYQRTVLCLARVLAGIQPTPWDKVQTLFRYCPQENAAGVFCLDTRAQDAVIALGIYFLEGGCQHEGQIVPYLLRLAKCLPKAVWIDDARSNKVERVRIPSAEKFSFCLNTLLSDIAAKCPDSREEIILNQVETLSALANIVKSSRDSSSAPPPIILCKATVPLLFGLARSMGRYASNDPPLLCRIFPPELLPIQKGGGRDGTGSSSSASGTCGGSFSSSERLAATHHFRPIIPRSMSGSLAQAQNASYDDGRQRCAGGKPSKPSLHSYFSVPYDPRTHFFTRYGSSFNQFPNMRVCESPTKGGPRPLYRVPPFPIQHLQTIFAVSKKLLTKDTLEHLDEQASDIFSLHQIKGYCYKSFSETLNLVLVTLLRELLQHQVDLPTPFTKDVQEFVKRLFLNGQTELQNKQQDQERERREENGIAVVNKYKVNVMANAACVDLLVWAIRDETEADKLCGRLSQKLNLELSHKIVMDHMPLLMVCLEGLGKLAHKFPNIAGTSISYLRDFLVAPSPILGKLHDHAMQSLAQQKKEKELTPFKIAVQHSDSRTAVVIYGDNQKPPGSGTGRSGHAAFESLRDAAIENLSIALRAAHTLDQFCVPALVANVSNRLFTAEKSGSESQGECHKSNLVSLNIIVMLGHVAVALKDTSKTTQNILQFFIQRFCKVPSEQNALIVDQLGCMIISQCETHVFDEIMKMFSRVTVQSASLAYTSDPEHRKQFHHVSDAVVNALGNIAANIQGDAEMLELLGKLLELFVQIGLDGERSYDNTPGAQKASSRAGNLGMLIPVIAVLVRRLPPIKNPRQRLHKLFKDFWAYCVVMGFTNARLWPADWYQGVQQIAAKSPLLISQTAHKSDMRELNYTLAIKSDSVNELRSQILVLLEHSSDNVATAINKLSFAQCTYLLSVYWLEMLRVENADEPSLEPIMSYLCDTALQRDKTGIWQCVKCVADQVFEKFRNVLYAHDEIREKVLESQATLLLVYFNHIHKPIQMVADQYLSFLVDRFPHLLWNRRVLWCMLDILQLLAYSLSLDPNEETPTLRVVSTPYTLQLMDSLPARELRLKDFADRCQGIVNEAMKWAPRSTRSHLQEYPNQIPTPVLAHHSGLALAFDSVVSSSAQHTGTMSKRPSCVNSDTPRFVSVLCLRSKYAGEISGLLSVLSEKDKAGLADRLVSDVWEACAEKSDARHRGALWRATAYLIICSEISRKLLHAVASSQLELFTESAMETAVECWQWVLTARQDLELCFIQEMVSAWQTTFEKRMGLFAWETEVTHPLAAYEGCKLVSKPILIAPHLIWLQLLSEMVDTAKYCNRDKVEMFCLLLHRCLPVLKSSKQNRQVSTVGCRFKLLQCGLSLLQGNTIPKSLSRNILRERIYSNALDYFCGPPTCPNQSREQLLEDIMILLKFWQTMRSEKKHLVTSEVGDYDLTNASVSSTQMLAVRNNPETASLISGGGLVNDYTRSMSASGNAVGMGMGVAGGGSSSGWYNTIPHSTSTLSKRSNRSKRLQYQKDSYDKDYMKKRNLILELLAVELEFLITWYNPNSLPDLIVPGEEQITEWRNRPYKSTVWRDYARLAWCYNPALAVFLPQRIKNAEIIDEEVSRLVCSDPIAVCHIPEALKYLCTTKNLLQESPDLVYILSWSPVTPIQALAYFSRQYPSHPLTAQYAVKTLSSYPAESVLPYIPQLVQALRHDTMGYVVEFIKNISRRSQIVAHQLIWNMQTNMYMDEDQQHKDPNLYEALDQLSQSIIASFSGAAKRFYEREFDFFGKITAVSGEIRSFAKGIERKNACLAALSRIKVQGGCYLPSNPEAMVLDIDYSSGTPMQSAAKAPYLARFRVYRCGITELETRAMEVSNNPNSQEDAKMTLGVESWQAAIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRDQLGRQTDSGLSEYFQHQYGDESSKEFQAARANFVKSMAAYSLIGYLLQIKDRHNGNIMIDKDGHIIHIDFGFMFESSPGGNIGFEPDMKLTDEMVMIMGGKMDSPAFKWFCELCVQAFLAVRPYQDAIVSLVSLMLDTGLPCFRGQTINLLKQRFVATKNNKEAAAHMLAVIRNSYQNFRTRTYDMIQYYQNQIPY
Protein: Uncharacterized protein (Q38B24)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAGPSNAECHIAVVEIICTEHLQRTLLMCDEATAFQRVVSERVAASGGKWTFEQYDFMLRHVVGDGDGDARNCRNEHLLALLREAGGERCWGGITAALRRREEFMQKEGLLLRRIAVAAKGIRRSGASLYPWCENQL
Protein: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase) (DNA 3'-phosphatase) (Three prime phosphatase) (Q03796)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Dephosphorylate DNA's 3'-phosphate termini. Has a role in the repair of breaks in single-stranded DNA.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histidine biosynthesis trifunctional protein
- Tyrosyl-DNA phosphodiesterase 1
- Histidinol-phosphate aminotransferase
- DNA-
- Imidazole glycerol phosphate synthase hisHF
- Apurinic-apyrimidinic endonuclease 1
- Telomerase reverse transcriptase
- DNA repair protein RAD16
- Telomere elongation protein EST1
- 1-
Sequence:
MSHKLTILPFLIKFTPKFPQSIDHDEHGLNVYAFDLDHTIIKPKSPNISFSRSASDWQFINFNSKKSTLDYLCNIIDNDPTAVIVIFSNQGGVITVPRTSKSCTKYTNKILLFLKAIKNDERGETLSHRLWLYAAPKRPKTFAANHSKITFASLGESYNNDPNIFEKVRKPMTGMVEFFKRDLESAYRVSEQISPIKLNWIYYCGDAAGRKKDFSDSDIKFAENLHVEFKYPEEIFHG
Protein: 3-ketoacyl-CoA synthase (EC 2.3.1.-) (Q2QCW7)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MPHFSNSVKLKYVKLGYQYLVNHILTLTLIPVMAGVLIEVLRLGPAGIVSLWNSLHFDLVHILCSCFFIIFVATVYFMSKPRSIYLVDYACYKPPVTCRVPFATFMEHSRLNLSNNPKSVEFQMRILERSGLGEETCLPPAIHYIPPTPTMEAARGEAEIVIFSAMDSLFKKTGLKPKDVDILIVNCSLFSPTPSLSAMVINKYKLRSNIKSFNLSGMGCSAGLISIDLARDLLQVHPNSNAVVVSTEIITPNYYQGKERAMLLPNCLFRMGGAAILLSNRRSERWRAKYRLVHVVRTHKGADDKAYRCVFEEEDKEGNVGISLSKDLMAIAGEALKSNITTIGPLVLPASEQLLFLLTLIGRKIFNPKWKPYIPDFKQAFEHFCIHAGGRAVIDELQKNLQLSAEHVEASRMTLHRFGNTSSSSLWYEMSYIEAKGRMKKGDRVWQIAFGSGFKCNSAVWKCNRTIKTPKDGPWADCIQGYPAHIPEVVKL
Protein: Metalloendopeptidase (EC 3.4.24.-) (B5XCQ9)
Organism: Salmo salar (Atlantic salmon)
Interaction partners:
Sequence:
MAPVFVLSIFIAVLCSVQGRSTGKVSFERSEEDMEIDGTSANSIEEDEYSASTLIEKANRNLGQRPDEPLVMFGDIAVYTGFMNADPCTARGCKWQKSSDGNVYVPFVISNEYSARERSVIEGGLRTFAASTCIRFFPRTNQRDFVDIQSQSGCFSFIGRRGNGQVVSLSRNGCVFLSVVRHELLHALGFNHEQTRSDRDSNVQILFQNIMPGMESNFRKINTINLGTPYDYNSVMHYSRFAFSRNRQPTILPIPDNNAVIGRATEMSPIDILRINRLYNCTGQQLD
Protein: Large ribosomal subunit protein uL4m (39S ribosomal protein L4, mitochondrial) (L4mt) (MRP-L4) (Q9DCU6)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9BYD3}.
Interaction partners:
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL36m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein bL20m
- Large ribosomal subunit protein bL19m
- Small ribosomal subunit protein bS16m
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein bL9m
Sequence:
MLRLFQAASRASLRLSGSRVIHSLAEGAERPAEISEPRDSAGLLDPVLRKCELRIPVHRRPVQAWVESLRGFEQERIGLAELHPDVFATAPRLDIVHQVAIWQRNFRRISYANTKTRAEVSGGGRKPWQQKGSGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLMQDDLHIVDSLELPTADPQYLTELAQYRHWGSSVLLVDLTHEEMPKNVVAATSGLNSFNLIPAVGLNVYSMLKHQTLVLTLPSVAFLEDKLLWQDSRYTPLYPFRLPYSDFP
Protein: F-box DNA helicase protein 1 (EC 5.6.2.4) (DNA 3'-5' helicase 1) (Q9USU3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in ATP-dependent DNA-unwinding in a 3' to 5' direction, and ATP-ase activities stimulated by the single-stranded DNA-binding protein ssb1. Essential for viability and normal growth of stationary phase cells and in the absence of either srs2 or rqh1 DNA helicase. Involved in DNA recombination repair of strand breaks and stalled or collapsed replication forks, on the rhp51-dependent pathway: promotes rhp51 filament dissolution from stalled forks, thereby inhibiting homologous recombination and preventing excessive recombination. Ubiquitination and DNA helicase activities are essential for controlling rhp51-dependent recombination in the absence of rad22. Plays a role in the processing of toxic recombination intermediates. Promotes proper chromosome segregation.
Subcellular location: Cytoplasm. Nucleus. Note=Becomes localized at discrete nuclear foci together with rhp51, in response to DNA strand breakage.
Interaction partners:
- Suppressor of kinetochore protein 1
- DNA repair protein rhp51
- Cullin-1
- RING-box protein pip1
- ATP-dependent DNA helicase srs2
- Ubiquitin-conjugating enzyme E2 4
- Cullin-4
- ATP-dependent DNA helicase hus2/rqh1
- DNA repair protein rhp57
- DNA repair and recombination protein rad22
Sequence:
MSAQHLHSCKFYRLPLEIIPLICRFLSVQDIQSFIRVFPSFQTILDSSNDLFWKKKNYELRIRRNRLLRGSYAAGVSSSAMNGFVNGTQISSTPAEREYYSKSDEIKNICGLPPGPMKVEQIGHAIDHLVSETHTVDHLGSSIKASFFHIDDVPLEWISSICMQVQSFFSPAAREAISSLKSRTTTSNLLLSLFVGILFEDDLWYFFNTLYMLSSTSAIEFAYFLDSIFTVVRTDYEHYRDPLSQTLITSCTRIHNIVAVIESPYDEPNTKGLTSEQKMIVECQLNPGEVLKVKAFAGTGKTKALLEFAKSRPKDKILYVAFNKAAKEDAELRFPFNVKCSTMHGLAYGAILAQADLPQAKLERQLSNSTIASLLSLQVAFPKANRKNNPGTPSASLVASHIMFTLNRFMHSTDWQLGFRHISKRSLEVTKLSKEKLLAYTKKLWSLIVNFEYTHAPLIPDAYMKLLHLYEFPNIFSKYDYILFDEAQDFTPCMVDLIYRQKHARIVIVGDAHQCIYGFRGANACAFNENLYPSTKQLCLTKSFRFGNSVAKYANFLLSLKGENVKLKGVQNDHAYWSSASNPNNVSGAFRFFPHTIIFRTNKELILQSIRLSVSLPKEIPIAILGSMRKKAFQLLRSGSELAHGQRPSHPKLKDFSSWGEFEVHVKNSAEEDAELALVYDMADELFSESFLSRLDNCEKRLMDSKDDGDNGIILATAHQSKGLEWDNVQLGNDFRPKFDSVSFSRIGSSRYLQEEINILYVALTRAKKRLILNDTITKLYALECGLVRFAGGILTEDQLQPGKVALFVDWQIDKFSFFYETPAEGYNLLVEANEKSVWDIFFGVLSGAWQNYIANTSERLKRSMLFIENQLFAVHDQ
Protein: Molybdenum cofactor guanylyltransferase (MoCo guanylyltransferase) (EC 2.7.7.77) (GTP:molybdopterin guanylyltransferase) (Mo-MPT guanylyltransferase) (Molybdopterin guanylyltransferase) (Molybdopterin-guanine dinucleotide biosynthesis protein A) (Molybdopterin-guanine dinucleotide synthase) (MGD synthase) (Protein FA) (P32173)
Organism: Escherichia coli (strain K12)
Function: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. Is also involved in the biosynthesis of the bis-MGD form of the Moco cofactor (Mo-bisMGD) in which the metal is symmetrically ligated by the dithiolene groups of two MGD molecules. Is necessary and sufficient for the in vitro activation of the DMSOR molybdoenzyme that uses the Mo-bisMGD form of molybdenum cofactor, which implies formation and efficient insertion of the cofactor into the enzyme without the need of a chaperone. Is specific for GTP since other nucleotides such as ATP and GMP cannot be utilized.
Subcellular location: Cytoplasm.
Interaction partners:
- Molybdopterin molybdenumtransferase
- Molybdopterin-guanine dinucleotide biosynthesis adapter protein
- GTP 3',8-cyclase
- Molybdenum cofactor cytidylyltransferase
- Molybdopterin adenylyltransferase
- Cyclic pyranopterin monophosphate synthase
- Respiratory nitrate reductase 1 alpha chain
- Probable pyruvate-flavodoxin oxidoreductase
- Fumarate and nitrate reduction regulatory protein
- Molybdopterin synthase catalytic subunit
Sequence:
MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALMTQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDTPYIPPDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMVFMRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR
Protein: Cytochrome P450 6a2 (EC 1.14.-.-) (CYPVIA2) (Cytochrome P450-B1) (P33270)
Organism: Drosophila melanogaster (Fruit fly)
Function: Is involved in the breakdown of synthetic insecticides and may be involved in the metabolism of insect hormones.
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Interaction partners:
- NADPH--cytochrome P450 reductase
- NADPH-dependent diflavin oxidoreductase 1
Sequence:
MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVERI
Protein: Aspartokinase (EC 2.7.2.4) (Aspartate kinase) (O60163)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Aspartate-semialdehyde dehydrogenase
- Homoserine dehydrogenase
- 4-aminobutyrate aminotransferase
- Aspartate aminotransferase, mitochondrial
- Aspartate aminotransferase, cytoplasmic
- Homoserine kinase
- Putative alanine aminotransferase
- Threonine synthase
- Argininosuccinate synthase
- Probable asparagine synthetase
Sequence:
MSIAKNIENDPSKGWVVQKFGGTSVGKFPIKIAVDVAKEYLSTKRVALVCSARSTDTKAEGTTTRLIRATEAALRPAVGSVHDLVRIIETDHVQAARDFIQDVGIQDELIDAFHADCVELEQYLNAIRVLSEVSPRTRDLVIGMGERLSCRFMAAVLKDQGIDSEFIDMSHIIDEQREWRNLDASFYAYLASQLASKVTAVGNKVPVVTGFFGMVPGGLLSQIGRGYTDFCAALLAVGLNADELQIWKEVDGIFTADPRKVPTARLLPLITPEEAAELTYYGSEVIHPFTMSQVVHARIPIRIKNVGNPRGKGTVIFPDTISRHGSATPPHPPKIMPDDISASLANKGATAVTIKDTIMVINIQSNRKISAHGFLASIFAILDKYKLAVDLITTSEVHVSMALYEESDDGNMHEAFVELRRLGTLDILHGLAILSLVGKHMRNTTGYAGRMFCKLAEAQINIEMISQGASEINISCVIDEKMAVKALNVIHKELLEPLALHEVPSQASMLVEKPWLYSA
Protein: Nitrate reductase (A0A0H3L9A0)
Organism: Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MTVTPRTGSRIEELLARSGRFFIPGEISADLRTVTRRGGRDGDVFYRDRWSHDKVVRSTHGVNCTGSCSWKIYVKDDIITWETQETDYPSVGPDRPEYEPRGCPRGAAFSWYTYSPTRVRHPYARGVLVEMYREAKARLGDPVAAWADIQADPRRRRRYQRARGKGGLVRVSWAEATEMIAAAHVHTISTYGPDRVAGFSPIPAMSMVSHAAGSRFVELIGGVMTSFYDWYADLPVASPQVFGDQTDVPESGDWWDVVWQCASVLLTYPNSRQLGTAEELLAHIDGPAADLLGRTVSELRRADPLTAATRYVDTFDLRGRATLYLTYWTAGDTRNRGREMLAFAQTYRSTDVAPPRGETPDFLPVVLEFAATVDPEAGRRLLSGYRVPIAALCNALTEAALPYAHTVAAVCRTGDMMGELFWTVVPYVTMTIVAVGSWWRYRYDKFGWTTRSSQLYESRLLRIASPMFHFGILVVIVGHGIGLVIPQSWTQAAGLSEGAYHVQAVVLGSIAGITTLAGVTLLIYRRRTRGPVFMATTVNDKVMYLVLVAAIVAGLGATALGSGVVGEAYNYRETVSVWFRSVWVLQPRGDLMAEAPLYYQIHVLIGLALFALWPFTRLVHAFSAPIGYLFRPYIIYRSREELVLTRPRRRGW
Protein: RecA family profile 1 domain-containing protein (Q384W8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA repair protein RAD51 homolog
- DNA repair protein, putative
- BRCA2 OB1 domain-containing protein
- DNA 3'-5' helicase
- Proliferating cell nuclear antigen
- Exonuclease, putative
- non-specific serine/threonine protein kinase
- Endo/exonuclease Mre11
Sequence:
MDALWPVAHDYANSNSDDDDDEGDDFVNLAQKPVVDLSDSDELTTQEADPLQMERVQVMLKKLEGLPGYGNGTRLENVLLQPPCDVSQMLDASLDDVELLYRHISHTIVNSPDSTLLPISVEDQLSSSCFGVISTGHKCLDDVLAGGVKCGLVTEITGASGTGKTALALNLAGRAATLAREGRGNGKYHTLWISSNQHPFSTRATAGYLRSTLGTYRGDNNGSNAAEPDRFGGDAETALQQLAIVTIPTLGQLLEHMPVLRENIMLNDGVRLVVVDDFSAMVRRTFTGMDGEVIERHNAVAALMNAMKSVAQDLRVAVVIITQSEVDLGHAFLYAVNTRLRLSRCLLQPNDAAADVAGNVRLAHLLELVKSCMASDCKFECKFEGFYLGSVHLLTEGAVALRDVDFYGVDPFGYAVVPTFVHC
Protein: Sulfotransferase (EC 2.8.2.-) (A0MGZ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MANLLSYVLFLALRAYAAPPEYIQRWPDGFTPAPGDPSNDSVTPSLIPPPGSSKHPPHSIIIGVRKGGTRALLEMLDIHPEVAAAATEVHFFDWDENYSKGFDWYREQMPYSYPTQITIEKTPGYFTSQVAPARIHAMNSSIRLLLILRDPTERVISDYTQVYFNRLENHKPVQAIENMLVKNGALNTRYKAIQRSLYDVHMRNWLQHFPLEQIHIVDGDTLIHDPLPELQRVERFLDLPPRIEASNFYFNQTKGFYCIRSDGHERCLHESKGRPHPPVNSNVLRQLRSYLRQHNRNFYRLIGRTFNWQ
Protein: ORF8 protein (ORF8) (Non-structural protein 8) (ns8) (P0DTC8)
Organism: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
Function: Plays a role in modulating the host immune response. May act as a secreted virokine by mimicking interleukin-17A (IL17A), and thereby binding to the IL17RA receptor, leading to activation of the IL17 pathway and increased secretion of pro-inflammatory factors. Contributes to the cytokine storm during SARS-CoV-2 infection. May act by down-regulating major histocompability complex class I (MHC-I) at cell surface. May inhibit expression of some members of the IFN-stimulated gene (ISG) family including hosts IGF2BP1/ZBP1, MX1 and MX2, and DHX58.
Subcellular location: Secreted {ECO:0000269|PubMed:35157849, ECO:0000269|PubMed:35343786}. Note=Is secreted during a normal viral infection by unconventional pathway (PubMed:35157849, PubMed:36689483). Its mRNA is expressed in cytoplasm and not spliced during a viral infection, but is spliced when expressed from cDNA in nucleus (PubMed:35157849). Splicing changes localization to host endosome and/or cytoplasm (PubMed:33060197, PubMed:34177923). May also localize in nucleus when fused with GFP (PubMed:34177923). {ECO:0000269|PubMed:33060197, ECO:0000269|PubMed:34177923, ECO:0000269|PubMed:35157849}.
Interaction partners:
Sequence:
MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRCSFYEDFLEYHDVRVVLDFI
Protein: TATA-binding protein associated factor TAFII135 (Q91WW6)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
ATLTPTVLAPRLPQPPQKPNNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAHAQAQPQSTMAPRPATPTGAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPTTTLQRSPGVQPQLVLGGSAQPASLGTATAVQTGTPQRTVPGASTTSTAATETMENVKKCKSFLSTLIKLASSGKQSTETAANVKDLVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQQPPASQATTALTAVVLSSSVQRTAGKTAASVTSALQPPVISLTQPTQVGVGKQAPPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNQLQPVPVVKPTVLPGTKALSTVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELVGTLTRSCKDDTFLLPAPLQRSTLEIGKKHGITDCHPDVVSYVSHATQQRLQNVVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQLRLKQKTKEMQQQELAQMRQRDANLTALAAIGPRKKRKVDCTGPGSGAQGSGPGAAVPGGSGVGTPRQFTRQRITRVNLRDLIFCLENERETSHSLLLYKAFLVTG
Protein: Curcumin synthase 2 (EC 2.3.1.217) (C6L7V8)
Organism: Curcuma longa (Turmeric) (Curcuma domestica)
Function: Catalyzes the synthesis of curcumin by condensing feruloyl-CoA with a diketide-CoA in the curcuminoid biosynthesis.
Interaction partners:
Sequence:
MAMISLQAMRKAQRAQGPATILAVGTANPPNLYEQDTYPDYYFRVTNSEHKQELKNKFRLMCEKTMVKRRYLYLTPEILKERPKLCSYMEPSFDDRQDIVVEEVPKLAAEAAENAIKEWGGDKSAITHLVFCSISGIDMPGADYRLAQLLGLPLAVNRLMLYSQACHMGAAMLRIAKDIAENNRSARVLVVACEITVLSFRGPDERDFQALAGQAGFGDGAGAMIVGADPVLGVERPLYHIMSATQTTVPESEKAVGGHLREVGLTFHFFNQLPAIIADNVGNSLAEAFEPIGIKDWNNIFWVAHPGNWAIMDAIETKLGLEQSKLATARHVFSEFGNMQSATVYFVMDELRKRSAAENRATTGDGLRWGVLFGFGPGISIETVVLQSVPL
Protein: protein-serine/threonine phosphatase (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1) (Q556S4)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 12
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome non-ATPase regulatory subunit 2
- 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome regulatory subunit 8
- 26S proteasome regulatory subunit 7
- 26S proteasome regulatory subunit 6B homolog
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome regulatory subunit 4 homolog
Sequence:
MDTIVSSSTTNPPTTTESTINSIITTTDSNSNNTNDNTTTNTTTTTTTTTTTNIINDSDLKTKTTTTTTTIINEENSKITIKTKWNGKEYKVLISKSSTVFDLKRQLETMTNVLSKRQKILGLSKGKQPTDEMIIESLSIQDNHSIIMMGTPESNIIADVPKTSGDTDEVFNDFEFDYIPDSDEISHIEKNKNQLLAMIERSNDISLINDPRPNKKLLVLDLDHTILDFKDQDVENMKRPHLEEFLVQSYQHYDIGIWSQTSWKWIEIKLTELGLLTNPRFKICFVMDQTLMFKVTTYRTINGKERTKIKHNVKALEVIWKHQHLGKFFSMKNTLHVDDLSKNFAMNPKNGVHVPPFKIKDAKKYGDNVLFHLTKYLKSISNEEDITLIDHKEWIRKIL
Protein: Uncharacterized protein A-270G1.2 (O75703)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRALENDFFNSPPRKTVRFGGTVTEVLLKYKKGETNDFELLKNQLLDPDIKDDQIINWLLEFRSSVMYLTKDFEQLISIILRLPWLNRSQTVVEEYLAFLGNLVSA
Protein: Euchromatic histone lysine methyltransferase 1 (A0A1B0GUD1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQCMATESVDHEVSTFVFI
Protein: Cyclin K (G3V2Q3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTS
Protein: D-psicose 3-epimerase (DPEase) (EC 5.1.3.30) (A8RG82)
Organism: Enterocloster bolteae (strain ATCC BAA-613 / DSM 15670 / CCUG 46953 / JCM 12243 / WAL 16351) (Clostridium bolteae)
Function: Involved in the biosynthesis of D-psicose. Catalyzes the reversible epimerization of D-fructose at the C3 position to yield D-psicose. The enzyme is highly specific for D-psicose and shows very low activity with D-tagatose.
Interaction partners:
Sequence:
MRYFKEEVAGMKYGIYFAYWTKEWFADYKKYMDKVSALGFDVLEISCAALRDVYTTKEQLIELREYAKEKGLVLTAGYGPTKAENLCSEDPEAVRRAMTFFKDLLPKLQLMDIHILGGGLYSYWPVDFTINNDKQGDRARAVRNLRELSKTAEECDVVLGMEVLNRYEGYILNTCEEAIDFVDEIGSSHVKIMLDTFHMNIEETNMADAIRKAGDRLGHLHLGEQNRLVPGKGSLPWAEIGQALRDINYQGAAVMEPFVMQGGTIGSEIKVWRDMVPDLSEEALDRDAKGALEFCRHVFGI
Protein: p44-71 outer membrane protein (Q2GK56)
Organism: Anaplasma phagocytophilum (strain HZ)
Interaction partners:
Sequence:
MRVRSYSNLFLAGVMASIVGVTVSNAAKADQDYGASLDARRSSHFYIGLDYSPAFSKIRDFKIIESSGETAAVYPYFDDGRSHAIEYNKFDWNTPNPRIGFKDNTLLAIGSSIGYAFSRARVEVEVGYESFKIKDRGKGGKKEKDGSAVYLLAKELAYSVASNQQDKLAVALSKVKGKDIVNFAKALESTSPTIGEKVCRTRSGSGEKNYARYVEKTSRSSNDTSLCGDIGGTSAHNSPRVNVFKDFAAKTLGDGSRNWPTSSGTKSMENDNANAVAADLVKNLNMEEKAIVAGLFSRTIEGGEAAKISAISTTSVMLNVCYDFYGKESSIAPYACAGIGSNFVGIVDSHIVPKLAYKLKAGIGCQISPEISIFAGGFYHRILGNGRYADLPVKRLFYDESPKGRTKNTAVANFSMSYAGGELGVRLAF
Protein: Dermatopontin (Early quiescence protein 1) (EQ-1) (Tyrosine-rich acidic matrix protein) (TRAMP) (Q9QZZ6)
Organism: Mus musculus (Mouse)
Function: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity (By similarity). Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Decorin
- Lumican
- Prolargin
- Periostin
Sequence:
MDLTLLWVLLPLVTTAWGQYGGYGYPYQQYQDYGDDGWVNLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDMISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV
Protein: Multiple C2 domain and transmembrane region protein 9 (Q8RXU9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:29259105}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:29259105}.
Interaction partners:
- 16 kDa phloem protein 2
Sequence:
MSNIKLGVEVISAQGLLQRDKHNSCSPFVELKFDNQIFRATTKHNDPNPVWHECFYFVVSDPSVLSTRTLEAHVYSYQNEFDAKPFLGKVRVNGTSFVPRSEAAPFNYPLEKRSVFSRARGELCLRVFITDDPSVTPSVPTPVPESPQAYSPSPRKEHVKSLITADASMATDERRELKPKTRTFHNSAPLVKQQPMMNYGIHEMRAAPMPPRVVQVNGPGPSLHQLPPDFSVKETSPLLGGGRIVGGRVVRGTERPTSGTYDLVEEMKFLYVRVVKARDLPNKDLTGSLDPYVVVKIGNFKGVTTHFNKNTDPEWNQVFAFAKDNLQSNFLEVMVKDKDILLDDFVGIVKFDLREVQSRVPPDSPLAPQWYRLENKRGEKKNYEIMLAVWSGTQADEAFGDATFSDSLVDSDSSNIISANLRSKVYHSPRLWYLRVQILEAQDVIIVSDKSRVPEVFVRVKVGNQMLRTKFPQRSNNPKWGDEFTFVVAEPFEDNLVLSVEDHTAPNRDEPVGKAVILMNDIEKRIDDKPFHDRWVHLEDSISDAMDVDKAKKVKFATRLRYKAVLDGGYHVFDESMYNSSDLRPSSRKLWKPAIGVLELGILNANVFHSMKTREGKGTSDTYVVAKYGHKWVRSRTVINSMNPKYNEQYTWEVFDPATVLTICVFDNAHFAAGDGGNKRDQPIGKVRIRLSTLQTGRVYTHAYPLLVLQPTGLKKRGELHLAVRFTCTSVSSMLMKYTKPLLPKMHYILPLSTNQQEALKMQAINIIIVRLGRSEPPLRREVVDYLTDWKSQLFSMRRSKANFNRFTTVFSGALSVWKWMEQVCTWKTPVTTALVHVLYTMLVTFPEMILPTVFLYMAVIGMWNYRFKPRFPPHMDAKLSYADNVNSDELDEEFDTFPTVRAPDIVKMRYDRLRSVAGKVQSVAGDIAAQGERVQALLSWRDPRATAIFVTFCFIIAMALYITPFKLVALLSGYYFMRHPKLRHRIPSAPVNFFRRLPAMTDSML
Protein: Thymidylate kinase (AtTMPK) (EC 2.7.4.9) (Protein ZEUS1) (Q0WW55)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the conversion of dTMP to dTDP (Probable). Involved in the regulation of DNA replication. Is essential to promote the first division of the zygote.
Subcellular location: [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:18036198}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:18036198}. Nucleus, nucleoplasm {ECO:0000269|PubMed:18036198}.
Interaction partners:
- Bifunctional dihydrofolate reductase-thymidylate synthase 2
- Bifunctional dihydrofolate reductase-thymidylate synthase 1
- Bifunctional dihydrofolate reductase-thymidylate synthase
- dCMP deaminase
- Thymidine kinase a
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- Thymidine kinase b
- Nucleoside diphosphate kinase II, chloroplastic
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
Sequence:
MKRICSVSSVQLFSRSFRALASPRSLNYPLQCIKRSSVRMESSNFSSGVRTESSVKPRGALIVLEGLDRSGKSTQCAKLLSFLNGLGHPTELWRFPDRETSVGQMISAYLSNKSQLDDHTIHLLFSANRWEKRSLMEEKLKTGTTLIVDRYSYSGVAFSSAKGLDIEWCKAPEIGLLAPDSVLYLDISPERAAERGGYGDERYERVEFQKKVADFYQTLGDSSWKIINASDAMEEVEKKIQQVVLDQVKECTEGKPLSLLWSS