wanglab/gogpt-training-data huggingface dataset:
Protein: Snustorr, isoform A (Q9VAU1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAPKKEATLSQQQTQQPIMDLERIKRHFSWSDPSAIISTDSAMAATNNDGGTQPNAVAAWGAPANGPRNTQAAVSVRHAFKAYGKKKNANQVLNNLNMTVPKGTIYGLLGASGCGKTTLLSCIVGRRYMDAGEIFVLGGKPGTRGSGVPGKRVGYMPQEIALYGEFSIQETMMYFGWIFGMDTKEILERLQFLLNFLDLPSEKRLVKNLSGGQQRRVSFAVALMHDPELLILDEPTVGVDPLLRQSIWNHLVHITKAGQKTVIITTHYIEEARQAHTIGLMRSGHLLAEESPSVLLSIYKCISLEEVFLKLSRIQSQKGDVTHVNFSNNISLHAMAFGSKMDKPSSSQEGGVVGLNFHQSKEVLINDSNGSIYTLNQEPYSPPPSRRNNNPNDEESCQDCYSNLCKITSKGKIRALLTKNMLRMWRNVGVMLFIFALPVMQVILFCLAIGRDPQGLNLAIVNGEMNDTVRENCYWEDGCHFKNLGCRYLSHLNTSVVKTYYEDLDDAKEAVRKGTAWGAVYISENFTDAFIARANLGRDSDDETIDSSEVKVWLDMSNQQIGVMLNRDIQLAFRDFAMGLLGQCGSNPKLGDVPIQFRDPIYGTMNPSFTDFVAPGVILTIVFFLAVALTSSALIIERTEGLLDRSWVAGVSPFEILFSHVITQFVVMCGQTTLVLIFMLVVFGVTNNGDLFWVIVLTLLQGMCGMCFGFLISSVCELERNAIQLALGSFYPTLLLSGVIWPIEGMPVVLRYISLCLPLTLATSSLRSILTRGWAILESDVYIGYVSTLSWIVGFLVLTLLVLRAKRG
Protein: Zinc finger protein ZXDC (ZXD-like zinc finger protein) (Q2QGD7)
Organism: Homo sapiens (Human)
Function: Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Zinc finger X-linked protein ZXDA
- MHC class II transactivator
- WD repeat-containing protein 5
Sequence:
MDLPALLPAPTARGGQHGGGPGPLRRAPAPLGASPARRRLLLVRGPEDGGPGARPGEASGPSPPPAEDDSDGDSFLVLLEVPHGGAAAEAAGSQEAEPGSRVNLASRPEQGPSGPAAPPGPGVAPAGAVTISSQDLLVRLDRGVLALSAPPGPATAGAAAPRRAPQASGPSTPGYRCPEPQCALAFAKKHQLKVHLLTHGGGQGRRPFKCPLEGCGWAFTTSYKLKRHLQSHDKLRPFGCPVGGCGKKFTTVYNLKAHMKGHEQESLFKCEVCAERFPTHAKLSSHQRSHFEPERPYKCDFPGCEKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFICDSDSCGWTFTSMSKLLRHRRKHDDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFECPVEGCCARFSARSSLYIHSKKHVQDVGAPKSRCPVSTCNRLFTSKHSMKAHMVRQHSRRQDLLPQLEAPSSLTPSSELSSPGQSELTNMDLAALFSDTPANASGSAGGSDEALNSGILTIDVTSVSSSLGGNLPANNSSLGPMEPLVLVAHSDIPPSLDSPLVLGTAATVLQQGSFSVDDVQTVSAGALGCLVALPMKNLSDDPLALTSNSNLAAHITTPTSSSTPRENASVPELLAPIKVEPDSPSRPGAVGQQEGSHGLPQSTLPSPAEQHGAQDTELSAGTGNFYLESGGSARTDYRAIQLAKEKKQRGAGSNAGASQSTQRKIKEGKMSPPHFHASQNSWLCGSLVVPSGGRPGPAPAAGVQCGAQGVQVQLVQDDPSGEGVLPSARGPATFLPFLTVDLPVYVLQEVLPSSGGPAGPEATQFPGSTINLQDLQ
Protein: Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2) (xLRRFIP2) (Q6GNW0)
Organism: Xenopus laevis (African clawed frog)
Function: May function as activator of the canonical Wnt signaling pathway upstream of ctnnb1/beta-catenin. Might be required for dorsal axis formation.
Interaction partners:
Sequence:
MGTPGSGRKRTQIKDRFSAEDEALSHIAREAEARLAAKRAARAEARDIRMRELERQQKELTHRYHDKKWGQIQKWMEDSDHARHLQRSSHRHSMASSRVTPNHRSSSVDVSGSHRGRESISRRRDSVYNTLKDSSRRTSNSYSNSYDVKNTTSSSHRDLLSGLYHDQRKYSSLKYNKPISTHHIRSSSLYSEPLATKRTYGTSLYKDGLYNASSSRAPSEYSCYSSRASSARSSPVCSDDEGSVSYSSCRGRRDSVSSDFSDQSESAADYFSRSNRRGSIVSDVDDVSIPDLNSLDEKTDKQFTTENYSRPSSRNATSGIPGTFTPLSGSSSRRGSGDASCSLDPDASLSELRDIYDLKDQIQDVEGRYMQGLKELRESLAEVEEKYKKAMVSNAQLDNEKSNLVYHVDTLKDVIEEMEEQMAEYHRENEEKSKELERQKHNCSILQHKLDEHKEGIRQRDEFIEENQRMQQRVDSLVREVYDLQETINWKDKKIGALERQKEYFDCIKNERDELRDELTAVKEKVKIGEKHGLVIIPDGTPNGDINHEPMVGAITVVSQEAAHVLESAGEGPLDVRLRKLAEEKEELVAQIRKLKLQKDDERQKSAKNNSTTTDPTGLENGSDLQLIEMQRDANRQISEYKFRLSKSEQDITTLEQNVMRLEGQVVRYKSAAENAEKVEDELKAEKRRLQRELRTALDKMEEMEMTNNHLVKRLEKMKANRTALLSQQ
Protein: Straw, isoform E (EC 1.10.3.-, EC 1.16.3.1) (A1Z6F4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Beta-alanyl-bioamine nonribosomal peptide synthetase ebony
Sequence:
MKAMDLNGFYQTFISFLIWGAFSNFPEVFAVRVANSQQNQPKKENQPDLTPMGSFWQQHVATPSSSTPFDSPFFSATHGLVQTHPSIGGSHSGPAPLNGNSLGSGAPSSILAGTKPALTAGSGYLNSRGSLPTSARYPANKITGTVVEPNPKSPFRHLDFSTSATAELRRNPALSAPDECARACREGEPPRICYYHFTLEYYTVLGAACQVCTPNATNTVWSHCQCVLADGVERGILTANRMIPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGSQYYDGVPFVTQCPIQQGNTFRYQWTGNAGTHFWHAHTGLQKLDGLYGSVVVRQPPSRDPNSHLYDFDLTTHIMLISDWLHEDAAERYPGRLAVNTGQDPESMLINGKGQFRDPNTGFMTNTPLEIFTITPGRRYRFRMINAFASVCPAQVTIEGHGMTVIATDGEPVHPVDVNTIISFSGERYDFVISADQPVGAYWIQLRGLGECGIRRAQQLAILRYARGPYQPASSPPTYDVGIPQGVVMNPLDAQCNRQRNDAICVSQLKNALEIDRGILAEKPDVKIFLPFRFFVYRAEDLFQPNTYNRFLVASDADHLISLIDEVSYISPPSPMLSQYNDIPQEYYCNGDNRPVDCGENCQCTHKIDVPLNAIVEVVLVDEVQQINISHPFHLHGTSFYVLGLGRSPDKQIQRMNLKHALELDQRGLLERQYLKPSLKDTVAVPNNGYAILRFRADNPGFWLFHCHFQYHIVIGMNLVFQIGTPNDLPPVPPNFPRCGNHLPPIKTI
Protein: Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3) (O75054)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- CD9 antigen
Sequence:
MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID
Protein: Glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97) (A0A8I6A9A8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MRRRRNTPKEALEGIWEQKRKRRNRREKRRSQTLGVPSPTPHLTPRRLRFSSLLNTTPSGSRFQQEQPWLPSWPHVISAPLDITSKNPTIPIQKLQDIQRAMELLSACQGPARNIDEATKRRYQFWDTQPVPKLNEVITSHGAIEPDKDNIRQEPYSLPQGFMWDTLDLSNAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKRMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPVATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIRAVRELINVYLKQFHLAPVMGDEEVAHWFLPREHIIDTFVVESPSGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMNDALIIAKLKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ
Protein: Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1) (P75390)
Organism: Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
Function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Interaction partners:
- Pyruvate dehydrogenase E1 component subunit beta
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
- Dihydrolipoyl dehydrogenase
- L-lactate dehydrogenase
- Pyruvate kinase
- Probable lipoate-protein ligase A
- Transketolase
- Glucose-6-phosphate isomerase
- NADH oxidase
- Fructose-bisphosphate aldolase
Sequence:
MAILIKNKVPTTLYQVYDNEGKLMDPNHKITLSNEQLKHAFYLMNLSRIMDKKMLVWQRAGKMLNFAPNLGEEALQVGMGMGLNENDWFCPTFRSGALMLYRGVKPEQLLLYWNGNENGSKIEAKYKTLPINITIGAQYSHAAGLGYMLHYKKLPNVAVTMIGDGGTAEGEFYEAMNIASIHKWNSVFCINNNQFAISTRTKLESAVSDLSTKAIAVNIPRIRVDGNDLIASYEAMHEAANYARSGNGPVLIEFFSWRQGPHTTSDDPSIYRTKEEEAEAMKSDPVKRLRNFLFDRGILTPQQEEEMVAKIEQEVQAAYEVMVSKTPVTLDEVFDYNYEKLTPDLARQKAEAKKYFKD
Protein: Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1) (Q9GZM8)
Organism: Homo sapiens (Human)
Function: Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity).
Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the cell body of the motor neurons and colocalizes with assembled neurofilaments within axonal processes. Localizes to the microtubules of the manchette in elongated spermatids. Colocalizes with DISC1 in the perinuclear region, including the centrosome (By similarity). Localizes to the interphase centrosome and the mitotic spindle. Localizes to the kinetochore in a CENPF-dependent manner. {ECO:0000250}.
Interaction partners:
- Platelet-activating factor acetylhydrolase IB subunit beta
- Disrupted in schizophrenia 1 protein
- Nuclear distribution protein nudE homolog 1
- 14-3-3 protein epsilon
- Nuclear migration protein nudC
- Ankyrin-2
- Rho GTPase-activating protein 1
- Serine/threonine-protein kinase PLK1
- Dixin
- Cyclin-dependent kinase 5
Sequence:
MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNGTKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (Q5ZJT4)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MTADEMKADGAPLEGTDITPKRDEGVLKVVKREGTGTESPMIGDKVTVHYTGWLLDGTKFDSSLDRRDKFSFDLGKGEVIKAWDIAVATMKVGEICQITCKPEYAYGLAGSPPKIPPNATLIFEIELFEFKGEDLTDDEDGGIIRRIRKKGEGYLKPNEGALVEIQFEGRYRDRAFDKRELRFEIGEGDNYDLPHGLEKAIQKMEKSEESIFYLKPNYGFGSTGKEKFQIPPDAELQYEVKLKSFEKAKESWEMNTEEKLEQSCMVKERGTQYFKEGKYKRAALQYKKIVLWLEHESGLSDEEDTKAKSLRLAAHLNLAMCHLKLKEYSQALENCNKALELDSSNEKGLFRRGEAHLAVNDFELARGDFQKVIQLYPSNKAAKVQLVTCQQKIREQHEKEKKMYANMFQRLADKELKPATTLQTSHTEDAEMKDEQNGVDDK
Protein: Candida glabrata strain CBS138 chromosome K complete sequence (Q6FM61)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- D-lactate dehydrogenase
- D-2-hydroxyglutarate dehydrogenase, mitochondrial
- Pyruvate kinase 2
- Pyruvate kinase 1
- Malic enzyme
- Pyruvate carboxylase
- Pyruvate carboxylase
- Pyruvate dehydrogenase E1 component subunit beta
- Pyruvate dehydrogenase E1 component subunit alpha
- Acetolactate synthase
Sequence:
MQRYIFKTPHSRVLRSLPRHAINSTTKRGIVSTRSSLNNQFFNSERQRKSYKWFWSIGLTVGLTAAIADNLHNKKDIYNDAKFDSSKPKISPSEVIKHNTPEDCWVVIDGYVYDLTNFIALHPGGPDIIKTNAGKDVTAIFDPIHPPDAIEKYIKPEQHIGPLDGKLDAEYICPPYAPGETPDDIARKAALRARLPPLSSIMNLYDFEYLASQILSKQAWAYYSSASDDEVSYRENHNAYHRIFFNPKVLVDVSKVDTSTEMLGHKVDVPFYVTATALCKLGNPKEGEKDIARGCGQGPNKTPQMISTLASCSVDEIVNAAPSKDQVIWYQLYVNSDRKITENLIKHVEDLGVKAIFVTVDAPSLGSREKDKKVKFNNTMSGPKSMKKSDVGESEGAAQTLSKFIDPSLSWQDIKILRKKTKLPIVIKGVQRVQDVVKAAEIGCNGVVLSNHGGRQLDFARAPIEVLAETMPVLKEKKLDKNFEVFVDGGVRRGTDVIKALCLGASGVGLGRPFLYANSCYGKDGVQKAIDLLKTEIEMNMRLLGVTSIKDMNPELLDLSSLHGRTVNVPKDSLYVNVYNKPELAEFLDDASD
Protein: Solute carrier family 22 member 22 (Prostaglandin-specific organic anion transporter) (Q8R0S9)
Organism: Mus musculus (Mouse)
Function: Sodium-independent organic anion transporter which exhibits high specificity for a subset of prostaglandins including prostaglandin E2 (PGE2), prostaglandin E1 (PGE1), prostaglandin F2-alpha (PGF2-alpha) and prostaglandin D2 (PGD2).
Subcellular location: Basolateral cell membrane {ECO:0000269|PubMed:20448048}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDFDEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAHHCSINLDNSRSEVSTDMNLTTEDLMKVSIPMGPNQKPEQCRRFRYTQWQFLDSNISTFNSTELETEPCLDGWTYDHSVFTSTIVTEWDLVCDFQSFKYYAQATSLAGHLVSCPLSGIISDRFGRKPLLMYCSLAYGAVGTYCAFAPNFSVYCVLRFLLSAFQSTILINSLILVLEEASVQWHPTIIVLSGLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFIFFVLFCWVPESVRWLIITGKTDQAWKELQRIASINGKKGIAQNLTTEDLRSKLKKDVNSTGKLFRIKDIFINPLIRKIVLSNSSLLFAELFSFVGLLLDVQLLGKNMFLTQIFLGAIDVPSKSLTYFTIRNVSRRPLIAFLLLTTGSCITITIFISEEMYVLRTIIFILGKGCFAAFTCISTTYINELSPVELRSTLNGVFLAVVRLAGVLSALTLATRKYFVYLPMILYGVLPIVATISILFLPETFNLPHTDIIKDMEKRKRLMSKNISKKEGQDFLETTEC
Protein: A2a adenosine receptor (Q4VQ10)
Organism: Sus scrofa (Pig)
Interaction partners:
Sequence:
NSVVNPFIYAYRIREFRQTFRKIIRSHILRQRELFKAGGTSARALAAHGSDAEQISLRLNGHPPGAWANGSAPQPERRPNGCALGLLSGGSVRECGGDTGLPDVELLSLELQGARPESPGLKATRAQDRAGVS
Protein: RNA helicase (EC 3.6.4.13) (A0A0D5W690)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MYELEKENLRRLSSYITAIIRPSLIKTFMTTYLKKETVERIMSTEQSSPSAAAQMLLDCMCDLEEDGWFQAFLDFLLTAEYSGLHDAIKNWNFLEYEELHEHRKLLERIEPSITKHLKPRELLMHMNCCLNQRESEEIQAVEAQRGPIAASEKLVDCLLRSDKSNWFKVLKMALDTCELYEALDLLETDGAGKSVQDSDCMMAESSTVCFEYREEMETENMAAPESCSHMSITETPAGVTGDSGRSGKRKLREYQRELMTAAVNGQNTIICAPTGCGKTIVALGICEEHLKLLRGRAKIAFLATKVDVYEQQYKLFQEHFSSKDPNIRVTGMCGDMALSVRMLIETHDIVVLTAQILVNALQSGEMENLQLLTLILLDECHNTTGKHPYNNIMTRYLDSKLTGNGSPLPQIVGLTASVGIGSFKNQMEAENNVTQLCANMDTRVITTVSKHLDELRSYVHTPEKEFFHVFQSPSDPFIRIIQNIMSNIEQMAKKTYNIESLSNISNREYGSQKYEQWIVSVQKSCRVLQMQNADGERRICRELCNYTEHLRKYNDALIINEDARTIDALDYLDVFFQQVRNAGFQTTERKLTALYDTQRPQLQCLATEGQQNPKLEELRFILEEEYHNNQETRTVMFVRTRALADAMKKWIDDTDTLKFLKPGVLIGKGRKSNFTGSGMTPSNQRGVLDTFKSSDQSKMLIATSVADEGIDIPQCNLVLMYEYVGNVVKMVQVRGRGRAQGSRCFLISSSAERIEKEKMNMMKERLVEAAIVALQSRPADLSFKVDILQKEDKARRDFLSASPDKPKTQDSFKLLCAKCKMFACQSDDLRVVQESHHIVVDRSIFSRCSRVPHRKPINFCGFSKKEKMLCVECKHDWGLVVSYLTIQDLPLLKIESFVVQNLVTGEQHYFRKWCKVTFAIREFDMTEITPETWALVN
Protein: Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) (P70429)
Organism: Mus musculus (Mouse)
Function: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10945997}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:10945997}. Cell projection, lamellipodium {ECO:0000269|PubMed:10945997}. Note=Targeted to the leading edge of lamellipodia and the distal tip of stress fibers through interaction with a number of proteins. In activated T-cells, localizes to the F-actin collar and the distal tip of microspikes. {ECO:0000269|PubMed:10945997}.
Interaction partners:
- Vasodilator-stimulated phosphoprotein
- Protein enabled homolog
- Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
- Actin, cytoplasmic 1
- Actin, cytoplasmic 2
- Profilin-2
- Profilin-1
- Zyxin
Sequence:
MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASSTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSTQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATGPILPPGHPSSAASTTLSCSGPPPPPPPPVPPPPTGSTPPPPPPLPAGGAQGTNHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT
Protein: PBX homeobox 1 (B1WC30)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGGYPSPCYQPDRRIQ
Protein: Peptidyl-prolyl cis-trans isomerase FKBP12 (PPIase FKBP12) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FK506-binding protein 12) (AtFKBP12) (FKBP-12) (Immunophilin FKBP12) (Rotamase) (Q8LGG0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Mediates rapamycin inactivation of TOR protein kinase activity.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Serine/threonine-protein kinase TOR
- FKBP12-interacting protein of 37 kDa
- Regulatory-associated protein of TOR 1
- Regulatory-associated protein of TOR 2
- Serine/threonine-protein kinase AtPK1/AtPK6
- NF-X1-type zinc finger protein NFXL1
- Small ribosomal subunit protein eS6z
- Microtubule-associated protein TORTIFOLIA1
- Target of rapamycin complex subunit LST8-1
- Major facilitator superfamily protein
Sequence:
MGVEKQVIRPGNGPKPAPGQTVTVHCTGFGKDGDLSQKFWSTKDEGQKPFSFQIGKGAVIKGWDEGVIGMQIGEVARLRCSSDYAYGAGGFPAWGIQPNSVLDFEIEVLSVQ
Protein: Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha 1 (PFP 1) (6-phosphofructokinase, pyrophosphate dependent 1) (PPi-PFK 1) (Pyrophosphate-dependent 6-phosphofructose-1-kinase 1) (Q9SYP2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulatory subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03185}.
Interaction partners:
- Glucose-6-phosphate isomerase, cytosolic
- Glucose-6-phosphate isomerase 1, chloroplastic
- transaldolase
- Aldolase-type TIM barrel family protein
- Transketolase-1, chloroplastic
- Transketolase-2, chloroplastic
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
- Mannose-6-phosphate isomerase 2
- Mannose-6-phosphate isomerase 1
- Fructose-bisphosphate aldolase 6, cytosolic
Sequence:
MDSDFGIPRELSPLQQLRSQYKPELPPCLQGTTVRVELGDGTTVAEAADSHTMARAFPHTLGQPLAHFLRETAQVPDAHIITELPSVRVGIVFCGRQAPGGHNVIWGLFEALKVHNAKSTLLGFLGGSEGLFAQKTLEITDDILQTYKNQGGYDLLGRTKDQIKTTEQVNAALKACTDLKLDGLVIIGGVISNTDAAHLAEFFAAAKCSTKVVGVPVTTNGDLKNQFVEANVGFDTICKVNSQLISNACTDALSAEKYYYFIRLMGRKHSHVALECTLQSHPNMVILGEEVAASKLTIFDIAKQICDAVQARAVEDKNHGVILIPEGLIVSIPEVYALLKEIHGLLRQGVSADKISTQLSPWSSALFEFLPPFIKKQLLLHPESDDSAQLSQIETEKLLAYLVETEMNKRLKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHICYHILAAGLNGYMATVTNLKSPVNKWKCGATPITAMMTVKHWSQDASYTLTSIGRPAIHPAMVDLKGKAYDLLRQNAQKFLMEDLYRNPGPLQYDGPGADAKAVSLCVEDQDYMGRIKKLQEYLDQVRTIVKPGCSQDVLKAALSVMASVTDVLTTISSNGGQ
Protein: Putative expansin-A17 (AtEXPA17) (Alpha-expansin-17) (At-EXP17) (AtEx17) (Ath-ExpAlpha-1.13) (Q9ZSI1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). Target of the transcriptional activator LBD18. Regulated by LBD18 to promote lateral root formation.
Subcellular location: Secreted, cell wall. Membrane; Peripheral membrane protein.
Interaction partners:
- Pectin lyase-like superfamily protein
- LOB domain-containing protein 18
- Plant intracellular Ras-group-related LRR protein 8
- Probable LRR receptor-like serine/threonine-protein kinase At4g36180
- Immune-associated nucleotide-binding protein 4
- Plant intracellular Ras-group-related LRR protein 7
- Probable xyloglucan endotransglucosylase/hydrolase protein 23
- Proline-rich family protein
- LOB domain-containing protein 21
- At3g53980
Sequence:
MTKIFSLLVAMIFSTMFFMKISSVSAGWLQAHATFYGGSDASGTMGGACGYGNLYTDGYKTNTAALSTALFNDGKSCGGCYQILCDATKVPQWCLKGKSITITATNFCPPNFAQASDNGGWCNPPRPHFDMAQPAFLTIAKYKAGIVPILYKKVGCRRSGGMRFTINGRNYFELVLISNVAGGGEISKVWIKGSKSNKWETMSRNWGANYQSNTYLNGQSLSFKVQLSDGSIKAALNVVPSNWRFGQSFKSNVNF
Protein: D(2) dopamine receptor (Dopamine D2 receptor) (G3MWM5)
Organism: Bos taurus (Bovine)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKEAARRAQELEMEMLSSTSPPERTRYSPMPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
Protein: Phospholipid phosphatase-related protein type 2 (Inactive phospholipid phosphatase PLPPR2) (Lipid phosphate phosphatase-related protein type 2) (Plasticity-related gene 4 protein) (PRG-4) (Q96GM1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAGGRPHLKRSFSIIPCFVFVESVLLGIVILLAYRLEFTDTFPVHTQGFFCYDSTYAKPYPGPEAASRVPPALVYALVTAGPTLTILLGELARAFFPAPPSAVPVIGESTIVSGACCRFSPPVRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCLPPSPDRPGPDRFVTDQGACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSPWEDLGQAPTMDSPLEKNPRSAGRIRHRHGSPHPSRRTAPAVAT
Protein: Large ribosomal subunit protein bL20m (39S ribosomal protein L20, mitochondrial) (L20mt) (MRP-L20) (Q9BYC9)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:11279069, ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042}.
Interaction partners:
- Small ribosomal subunit protein uS15m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein bL9m
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL22m
- Large ribosomal subunit protein uL3m
- Small ribosomal subunit protein uS13
Sequence:
MVFLTAQLWLRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYLKKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYEPKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH
Protein: Shavenoid, isoform A (A1Z8J5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRLQSLPLLLLLAVVTLPPATPTSAARPLTHPRARNHYPSEDLAEEPLMPASLLLEELQQTNGQLVNLTRQHDGDTFHTSGLSSACNADTCIGLSSGTASLVRSTGDGSGQGNDGLNPATSSLGGGQMELLTRRLKLQKGRGQVANIDASGETGCTCRCLPYQRAYREDLGICVDDIHECSLSPFVSGSSSEKIPFVFLPLKGQIIYPSREISFASIHTPVCAVTGAQYLGSNGWSDLRNPIDTDYPFRMFRDEGRSFLLWLGEADLRQKMQGRLIVVHLVCRDMTVALNASNHVKGEPLMPPRNVHSPCVAFRVNGSPVKYAHNVPEVFFQPANSTTLASTSDGMTMREYVVIGICSLLLGLIYVASVFLYLYMKKRKRHSSRHSLDNLTNDINYPKNDQVTYGAPFSRVGSIYSSNSMGLGNGNESNTRTSIGSLKEDMGIVKNNPLLQHFPQLSEREHNSGFASDISNSNSECEMEEKIKTSVLVHPQLSKSPKPSGGTDNAAMDVDDFLQDNECLPAENVAVIDELMSEEKLENLRAMVSGNVRKKLYFNPAYFEPHLLAEPPQAAIEFLQKIREVIAIAKYKMASKRYQPSLNIIPEEQHPESSSSSPMFNIPLQQSLAGKGMGDKRNSIEQWLQSVPNSDATPAPKTLDRPAPPTAKKPSSGSPNKGSLRKEISAPKERPPPPPMQKSKADEGNAKSSSPAPSGPHSSRSTGKSSPEQSPKPKTNVGSTYEGFSAFSVAANVYGFAETGGEIYNNPKFMLADSPAASLRSASSRSKSMKKRSEVLDQFAAANSTPTSLTSFDRQHYNMLRNMKAPEVIYDSLKREFAAHIPTPDYDSTIEKRIKDIYSSTQSSIPSVPTPDYSSLSRKSLKQFQPDSPIYRRKSPQYLIVDYETDSLERLEPSKRKSSHSSSSPSSDVSSQLSPSLSTALPLEEEMEISHTVYDRMNGFRKEGEMKKRLAAKHQHPHPGQQQRQKEAAARIKYDTPFRGSMTIEVEHEPPSDLERTDSDQFEPDTLDRKPKKQSFCDISAWDGHKPIDSDFSQISSLPDLSRQISPAPNQGIKPRTASFILRSSNSFRNLREIYESPLIAQDNIKYEKKVAQTPEEEGRILTLEAKHSRRQRLMETSPTHSVMDITKVNKTTITISSPKPADKAPPTRPKVNQHYCPPLVQSKRPLPPPPPNSSEHQAPDEDAYSLHSEITGTSEFENSCNNTMSSAISATTEERTHAKGSRSPKINAKIPEEDYEGMYNKKINSLRNDYSLTKYLNRRKSQREEVSKAGPDSPKDVAPEPEFGGSNKSVKEVDVAQFDALSISSRSNRSSSHLSERTKEMYRNAGVPVGIAYPQRAASSSGNASAGGNVQTVYRCEIEQAQLTAGMQIAIGLKDRAKKAKDLKNAWRKFVTMAANKFSPSQSPAPTYGSKTAAGFLEDDGIASIIEDAAQSAGMGQPGSQTYYEQRFGQLDSGYMSTDSTELYKRNVYDRYNFKMPCGRGQIIRVDTIEDNEEESGPNDNRFEDLEHMVSPSHSRRSPENNAVVACDLSDAESDKTLTRSHSQTNSQERNVRGSTTTMSSYSSDENGRGRSTCCGSSETDEETNAEDMWESGAESIETHSVLYKMIRKS