wanglab/gogpt-training-data huggingface dataset:
Protein: Ras and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2) (Q8WYP3)
Organism: Homo sapiens (Human)
Function: Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Ras-related protein Rab-5A
- Ras-related protein Rab-5B
- Fibulin-5
Sequence:
MTAWTMGARGLDKRGSFFKLIDTIASEIGELKQEMVRTDVNLENGLEPAETHSMVRHKDGGYSEEEDVKTCARDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVHKSTKMQKKVLSLRLPCEFGAPLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKSEAQLEELAQMGLNFWSSPADSKPPNLPPPHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSGGLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIKSKKKRSSSFVLPKLVKSQLQKVSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLQENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSETRDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQICAEKFKVGDPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGIIFQNGEEDLTTS
Protein: 4-hydroxybutyrate--CoA ligase 2 (EC 6.2.1.40) (Acetate--CoA ligase) (EC 6.2.1.1) (Butyrate--CoA ligase) (EC 6.2.1.2) (Propionate--CoA ligase) (EC 6.2.1.17) (acyl-activating enzyme) (A4YDR9)
Organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Function: Catalyzes the ligation of coenzyme A (CoA) to 4-hydroxybutyrate (4HB). It can also use butyrate, valerate, propionate, acetate and 3-hydroxybutyrate (3HB) as substrates.
Interaction partners:
- Large ribosomal subunit protein uL6
- 4-hydroxybutyrate--CoA ligase 1
- Acetate--CoA ligase
- Large ribosomal subunit protein uL2
- Superoxide dismutase
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL13
Sequence:
MGGFKIPNYEGVDPTGSWYSVLTPLLFLERAGKYFKDKTAVVYRDSRYTYSTFYDNVMVQASALMRRGFSREDKLSFISRNRPEFLESFFGVPYAGGVLVPINFRLSPKEMAYIINHSDSKFVVVDEPYLNSLLEVKDQIKAEIILLEDPDNPSASETARKEVRMTYRELVKGGSRDPLPIPAKEEYSMITLYYTSGTTGLPKGVMHHHRGAFLNAMAEVLEHQMDLNSVYLWTLPMFHAASWGFSWATVAVGATNVCLDKVDYPLIYRLVEKERVTHMCAAPTVYVNLADYMKRNNLKFSNRVHMLVAGAAPAPATLKAMQEIGGYMCHVYGLTETYGPHSICEWRREWDSLPLEEQAKLKARQGIPYVSFEMDVFDANGKPVPWDGKTIGEVVMRGHNVALGYYKNPEKTAESFRDGWFHSGDAAVVHPDGYIEIVDRFKDLINTGGEKVSSILVEKTLMEIPGVKAVAVYGTPDEKWGEVVTARIELQEGVKLTEEEVIKFCKERLAHFECPKIVEFGPIPMTATGKMQKYVLRNEAKAKANKEKS
Protein: Javelin-like, isoform G (A0A0B4K6X6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MECLPMSSAAHHPHLMAGASAVGAVSASPTATVVVGATYPHHLHHHHLSHHTPYSNSYGSHHIHSEQTKSLQELQHEVGALLEFRDLVIETFPDLKHKMASMSATPSTPTSSVGAIGGSHSVGGGSSSLATRREWEPGIRMKRKQSHKEPSTSSAAAAPSSGAEASSSSLTRSRSNSHSGKKEPKSGENNNGSVVQDSGFSTETSSSKEGHSASSTNGAMTVAIAANRLSCAESDDELLNLLDVIHRKSNRLREEVEHLQSYERQHGDAQKTGGEGQGASKEGMTAQQFREQVERLNREDIKQLRKERDRLLDKLAEMEAETLTGRIKAAKMSDQVEELVGVKKDLEEQLKLAMAQKLELSSRVQQLQQQQQSKSSSSGSQSDYSSQRNFLSSATTVLSNGSRPSSNVISNNTFQPVVLDQPAQEAFHQSPGSDIPLRKQQQQSLGRLDGIVSTPGTRNSKCRLTDSKRFAAILLETNVLELQRHLLTLTVQNQVLAQKLESSSKSKTLLAKRLDKNSEEFEHLRYQLEEKNIELEGTKAQLRLVESRLQASNSTSNSYLHSSQHDYETNRSSASTTLMLSRRGVSDSVDSTSTAMPAPPVTQISTPSMKAMVPLAMDELQQHSSSTESAHEHENQGLQTPNSTSSPLSKTIINASPCPVGSSTPSNIAARVMSISVGGVSPFEAMTPPPRQNAFRKFGSASKPSKIPLPGSKAAAYFSGKPPTGRPSTAGRSPPSANNSSSTSYGSKSSLSRSTGNLQSLRRAETSASNHSLSTNTSRSSTSSSIPLATTPYSSGSTGNRSQPTAATTPSPRVLQNSPLPKLKRDTISSRVRHLDSLSRAQQTPEGLKGTTTNSTSIAAQLSSTLRKDLQLSGNGTGAPYNQHHLNHRRSGHSPASNSSGSGVSRRYSSASTGGSGGRAIGRDQGEPTTPTSSYGGDSDSGKNLANTVEKPNFRLNNQNWQLWQTSSSSQGKIQMERYLPHELHDVSEETAYDSYYTEYTTPDSMDCGSANLLVTFDYGYCDSMEARANPAAPEDDDRCDGVDPDYGGDGCADEVDAIWFGTPPRDKKDEKLFEVHHVQHKLLDDSMQSLISYDVDDFEEELSEPDPDEEIFYDSIECV
Protein: E3 ubiquitin-protein ligase RGLG2 (EC 2.3.2.27) (RING domain ligase 2) (Q9LY87)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase that mediates the formation of 'Lys-63'-linked ubiquitin chains. Regulates apical dominance by acting on the auxin transport proteins abundance. Mediates ubiquitination and subsequent proteasomal degradation of ERF053 in response to drought stress. Acts as a negative regulator of drought stress response.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Nucleus {ECO:0000269|PubMed:22095047}. Note=Translocates to the nucleus under salt stress. {ECO:0000269|PubMed:22095047}.
Interaction partners:
- Ethylene-responsive transcription factor ERF053
- Ubiquitin-conjugating enzyme E2 35
- Ubiquitin-conjugating enzyme E2 13
- Ubiquitin-conjugating enzyme E2 36
- Probable E3 ubiquitin-protein ligase XERICO
- E3 ubiquitin-protein ligase AIP2
- At2g14110 superfamily protein)
- E3 ubiquitin protein ligase DRIP1
- U-box domain-containing protein 14
- E3 ubiquitin-protein ligase SDIR1
Sequence:
MGTGNSKENWRQSSFRSTSASSASPSSSSWASQQSYPQYGAESYNYPPPPSYAQPPEYTQPPPPLYSTQPYSAPSYSAPPSQSYGSDNKKRLERKYSKISDDYSSLEQVTEALARAGLESSNLIVGIDFTKSNEWTGARSFNRKSLHFIGSSPNPYEQAITIIGRTLAAFDEDNLIPCYGFGDASTHDQDVFSFNSEDRFCNGFEEVLSRYKEIVPQLKLAGPTSFAPIIDMAMTIVEQSGGQYHVLVIIADGQVTRSVDTENGQLSPQEQKTVDAIVQASKLPLSIVLVGVGDGPWDMMREFDDNIPARAFDNFQFVNFTEIMAKNKAQSLKETEFALSALMEIPQQYKATIELNLLGRRNGYIPERFPLPPPMRGGSSSYNSPKPSRLPSFKPSVPPHPTEGYHVRSSPVPPPTSSASDNQLCPICLSNPKDMAFGCGHQTCCECGPDLQMCPICRAPIQTRIKLY
Protein: DNA-binding transcription factor NET (FI03708p) (FI10001p) (Q7KH24)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSFAAMANTNTEKLYMQLSASELSAIIMKDSPNSNDRDAGFCSASSESEGGDDLVVEHARSGSPDIRPKGTDSADSKPIALVRNKRKSSEPFKVVGLTTPNSKSMPGPPSSASMNATGPLKKRIRYTSSADSAVVLTPPAIDSPPPNSCIPSTLRLQHEIMPNPAHIYVRHPGVTTLHRSLAAHPEQLEPLALVTTKKQCVDQAGPKIEAFSALLIGKQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGLAPISRPHQHQRNYKNMTRERRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLSRMAGEDYSADQSVPSIATCLEAVTSTIQTEGKVKRKKDE
Protein: Syncytin-2 (ERV-FRD provirus ancestral Env polyprotein) (Envelope polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)] (P61558)
Organism: Pongo pygmaeus (Bornean orangutan)
Function: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (By similarity).
Subcellular location: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Surface protein]: Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM. {ECO:0000250|UniProtKB:Q9UQF0}.; SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGLLLLVLILTPLLAAHRHPDFPLLEKAQQLLQSTGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYHWDPNLKGLMRPANSLLSTVKQDFPDIRQKPPIFGPIFTNINLMGIAPICVTAKRKNGTNVGTLPSTVCNVTFTVDPNQQTYQTYTHKQFLHQPRFPKPPNITFPQGTLLDKSTRFCQGRPSSCSTRNFWFRPADYNQCLQISNLSSTAEWVLLDQTRNSLFWENKTKGANQSQTPCVQVLAGMTIATSYLGISAVSEFFGTSLTPLFHFHISTCLKTQGAFYICGQSIHQCLPSNWTGTCTIGYVTPDIFIAPGNISLPIPIYGNSQLPRVRRAIHFIPLLAGLGIIAGTGTGIAGITKASLTYSQLSKEIAKNIDTMAKALTTVQEQIDSLAAVVLQNRRGLDMLTAAQGGICLALDEKCCFWVNQSGKVQDNIRQLLNQASSLRERATQGWLNWEGTWKWFSWVLPFTGPLVSLLLLLLFGPCLLNLITQFVLSRLQAIKLQTNLSAGCRPHNIQESPF
Protein: Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog) (Q96KR1)
Organism: Homo sapiens (Human)
Function: Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasmic granule {ECO:0000250}. Chromosome {ECO:0000250}. Note=Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules (By similarity). {ECO:0000250}.
Interaction partners:
- Interleukin enhancer-binding factor 2
- Heterogeneous nuclear ribonucleoprotein R
Sequence:
MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAAAAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHTATDYGYTQRQQEAPPPPPPATTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAETYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTAVTYSGTSYSGYEAAVYSAASSYYQQQQQQQKQAAAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQNTSSSNSSTRGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQATSSTAVSASKPTASPSSIAANNCTVNTSSVATSSMKGLTTTGNSSLNSTSNTKVSAVPTNMAAKKTSTPKINFVGGNKLQSTGNKAEDIKGTECVKSTPVTSAVQIPEVKQDTVSEPVTPASLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQHHWDDRRRMPDGGYPHGPPGPLGLLGVRPGMPPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEKNKNKEGDDKKEGGKDRALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKTLLSRIAENLPKQLAVISPEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMSQRFNIHNNRKRRRDSDGVDGFEAEGKKDKKDYDNF
Protein: Homeobox containing 1 (H0YLF2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEEGRSSEGGRE
Protein: Cardiolipin synthase (CMP-forming) (CLS) (EC 2.7.8.41) (Q07560)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:9442089}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
- Phosphatidylglycerophosphatase GEP4, mitochondrial
- Phosphatidate cytidylyltransferase
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
- Tafazzin
- Cardiolipin-specific deacylase 1, mitochondrial
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- Lysophospholipid acyltransferase
- Phosphatidate cytidylyltransferase, mitochondrial
Sequence:
MIQMVPIYSCSALLRRTIPKRPFYHVLSGLTVRFKVNPQLNYNLFRDLTRREYATNPSKTPHIKSKLLNIPNILTLSRIGCTPFIGLFIITNNLTPALGLFAFSSITDFMDGYIARKYGLKTIAGTILDPLADKLLMITTTLALSVPSGPQIIPVSIAAIILGRDVLLAISALFIRYSTLKLKYPGRVAWNSYWDIVRYPSAEVRPSQLSKWNTFFQMVYLGSGVLLLLYEKEEGCEKTEEDFEDRKQDFQKAFSYLGYVTATTTIMSGVSYALKRNAFKLLK
Protein: Nucleosome assembly protein 1-like 1 (Q19007)
Organism: Caenorhabditis elegans
Interaction partners:
- Histone H2A.V
- Histone H2A
- Histone H2A
- Histone H2A
- Cytoplasmic FMR1-interacting protein homolog
- Small ribosomal subunit protein eS6
- Serpentine receptor class alpha-1
- Large ribosomal subunit protein eL39
- Serine/threonine kinase SAD-1
- Protein SDA1 homolog
Sequence:
MADQEHIDAGLLSTNFDMIQALPLNVKQRVCALKNLQMKTIQIESDFYKRVHELEIEFEGKFKSTFDQRKAIVAGEVEPTKEQIDTPILEGLEGDQLAELYKAAEADPSAKGIKDFWLTALRTHDLVAEAIEEHDVPILSYLTDVTTAASKDPAGFKIEFHFATNPYFKNQVLTKTYLLGFDPDAEAPLQFDGPHVIRAVGDTIEWEDGKNVTKKAVKKKQKKGANAGKFLTKTVKADSFFNFFEPPKSKDERNEDEDDEQAEEFLELDYEMGQAIRDTIIPRAVLFYTGELQSDDMFDFPGEDGDDVSDFSDDEA
Protein: GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed] (P01116)
Organism: Homo sapiens (Human)
Function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22431598, ECO:0000269|PubMed:23698361, ECO:0000269|PubMed:29239724}; Lipid-anchor {ECO:0000269|PubMed:29239724, ECO:0000305|PubMed:23698361}; Cytoplasmic side {ECO:0000305|PubMed:23698361}. Endomembrane system {ECO:0000269|PubMed:29239724}. Cytoplasm, cytosol {ECO:0000269|PubMed:23698361}.; SUBCELLULAR LOCATION: [Isoform 2B]: Cell membrane {ECO:0000269|PubMed:28619714}; Lipid-anchor {ECO:0000305|PubMed:28619714}.
Interaction partners:
- Ral guanine nucleotide dissociation stimulator
- Serine/threonine-protein kinase B-raf
- Son of sevenless homolog 1
- RAF proto-oncogene serine/threonine-protein kinase
- Calmodulin-like protein 5
- Calmodulin-like protein 3
- Calmodulin-1
- Calmodulin-like protein 6
- Calmodulin-like protein 4
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM
Protein: ORF6 protein (Accessory protein 6) (Non-structural protein 6) (Q19QW5)
Organism: Severe acute respiratory syndrome coronavirus (SARS-CoV)
Subcellular location: Host Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004217}. Host endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004625}.
Interaction partners:
Sequence:
MFHLVDFQVTIAEILIIIMRTFRIAIWNLDVIISSIVRQLFKPLTKKNYSELDDEEPMELDYP
Protein: Dynein axonemal light chain 1 (Q8IB59)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}.
Interaction partners:
- Dynein intermediate chain, putative
- Dynein intermediate chain, putative
Sequence:
MSRTMAKEATFSNCIKNWEQKNGKKICDEEEVSFICNIPLIEKLDNSINTLEKCKRLSLSTNRIEKLIPMSGLKNIEILSLGRNCIKKIQYLEDISGTLKQLWLSYNYIDKLDNLQSLKKLQVLYIFHNKIKSIEEIDKLNTLPELVELGLKGNPIYEGKTNEYMKLLILKKLPQLKIVDNETITEKQRNDALTFEILP
Protein: Alanine--glyoxylate aminotransferase (AGT) (EC 2.6.1.44) (Serine--pyruvate aminotransferase, mitochondrial) (SPT) (EC 2.6.1.51) (P09139)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification.
Subcellular location: [Isoform Peroxisomal]: Peroxisome {ECO:0000250|UniProtKB:P21549}.; SUBCELLULAR LOCATION: [Isoform Mitochondrial]: Mitochondrion matrix {ECO:0000269|PubMed:6725236}.
Interaction partners:
- Glyoxylate reductase/hydroxypyruvate reductase
- Phosphoserine phosphatase
- 2-Hydroxyacid oxidase 1
- Threonine aldolase 1
- Alanine--glyoxylate aminotransferase 2, mitochondrial
- Serine hydroxymethyltransferase
- Serine hydroxymethyltransferase
- 2-Hydroxyacid oxidase 2
- 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
- Apolipoprotein A-V
Sequence:
MFRMLAKASVTLGSRAASWVRNMGSHQLLVPPPEALSKPLSIPKRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMFQIMDEIKQGIQYVFQTRNPLTLVVSGSGHCAMETALFNLLEPGDSFLVGTNGIWGIRAAEIAERIGARVHQMIKKPGEHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYQCLLLVDSVASLGGVPIYMDQQGIDILYSGSQKVLNAPPGISLISFNDKAKSKVYSRKTKPVSFYTDITYLSKLWGCEGKTRVIHHTLPVISLYCLRESLALISEQGLENSWRRHREATAHLHKCLRELGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFNIEISGGLGPSEDKVLRIGLLGYNATTENADRVAEALREALQHCPKNKL
Protein: Transcription factor MYB82 (Myb-related protein 82) (AtMYB82) (Q9LTF7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activation factor positively regulating trichomes development. Has a function nearly equivalent to that of GL1 and can complement gl1 mutants.
Subcellular location: Nucleus {ECO:0000269|PubMed:24803498}.
Interaction partners:
- Transcription factor GLABRA 3
- Transcription factor EGL1
Sequence:
MECKREEGKSYVKRGLWKPEEDMILKSYVETHGEGNWADISRRSGLKRGGKSCRLRWKNYLRPNIKRGSMSPQEQDLIIRMHKLLGNRWSLIAGRLPGRTDNEVKNYWNTHLNKKPNSRRQNAPESIVGATPFTDKPVMSTELRRSHGEGGEEESNTWMEETNHFGYDVHVGSPLPLISHYPDNTLVFDPCFSFTDFFPLL
Protein: Vicilin-like antimicrobial peptides 2-3 (MiAMP2) (Vicilin-like protein Mac i 1) (allergen Mac i 1.0101) [Cleaved into: Antimicrobial peptide 2a (MiAMP2a); Antimicrobial peptide 2b (MiAMP2b); Antimicrobial peptide 2c-1 (MiAMP2c-1); Antimicrobial peptide 2c-2 (MiAMP2c-2); Antimicrobial peptide 2c-3 (MiAMP2c-3); Antimicrobial peptide 2d (MiAMP2d)] (Q9SPL3)
Organism: Macadamia integrifolia (Macadamia nut)
Function: Antimicrobial peptides 2b, 2c and 2d have antibacterial and antifungal activity against a range of species.
Subcellular location: Secreted {ECO:0000269|PubMed:10571855}.
Interaction partners:
Sequence:
QCMQLETSGQMRRCVSQCDKRFEEDIDWSKYDNQEDPQTECQQCQRRCRQQESDPRQQQYCQRRCKEICEEEEEYNRQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEGDNKRDPQQREYEDCRRHCEQQEPRLQYQCQRRCQEQQRQHGRGGDLMNPQRGGSGRYEEGEEKQSDNPYYFDERSLSTRFRTEEGHISVLENFYGRSKLLRALKNYRLVLLEANPNAFVLPTHLDADAILLVIGGRGALKMIHRDNRESYNLECGDVIRIPAGTTFYLINRDNNERLHIAKFLQTISTPGQYKEFFPAGGQNPEPYLSTFSKEILEAALNTQTERLRGVLGQQREGVIIRASQEQIRELTRDDSESRRWHIRRGGESSRGPYNLFNKRPLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLSGRHGGRGGGKRHEEEEEVHYEQVRARLSKREAIVVLAGHPVVFVSSGNENLLLFAFGINAQNNHENFLAGRERNVLQQIEPQAMELAFAASRKEVEELFNSQDESIFFPGPRQHQQQSPRSTKQQQPLVSILDFVGF
Protein: Pathogenesis-related protein 10 (Q29SB6)
Organism: Zea mays (Maize)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Blue copper protein
- 40S ribosomal protein S10-1
- Peroxidase
- Peroxidase
- KDEL-tailed cysteine endopeptidase CEP1
- Ribonuclease 1
Sequence:
MASANSWTLEIASPVAPQRLFRAAVMDWHTLAPKVASHVVASAQPVEGDGGVGSVRQFNFTSVMPFSFMKERLEFLDADKCECKNTLIEGGGIGVAIETATSHIKVEPAAGGGSVVKVESTYKLLPGVEVKDEIAKAKESVTAIFKGAEAYLVANPDAYN
Protein: Odorant binding protein a (Odorant-binding protein 56i) (Q8MVX7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MHFFACCALLLVVVTLPTCFVQAGPIKDQCMAAAGITAQDVANRHETDDPGHSVKCFFRCFLENIGIIADNQIIPGAFDRVLGHIVTAEAVERMEATCNMIKSETTYDESCEFAWQISECYEGVRLSDVKKGQRTRNHRG
Protein: Zinc finger protein 395 (E5RGF1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASVLSRRLGKRSLLGARVLGPSASEGPSAAPPSEPLLEGAAPQPFTTSDDTPCQEQPKEVLKAPSTSGLQQVAFQPGQKVYVWYGGQECTGLVEQHSWMEGQVTVWLLEQKLQVCCRVEEVWLAELQGPCPQAPPLEPGAQALAYRPVSRNIDVP
Protein: Pituitary homeobox 1 (Homeobox protein PITX1) (Paired-like homeodomain transcription factor 1) (cPTX1) (P56673)
Organism: Gallus gallus (Chicken)
Function: Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. Acts as a transcriptional activator by binding to promoter sequences with a TAAT/GCC core motif.
Subcellular location: Nucleus.
Interaction partners:
- T-Box protein 4
- T-box transcription factor TBX5
Sequence:
MDSFKGGMNLERLPESLRPQPSHDMASSFHLQRSSEPRDPIENSASESSDTDVPEKERSESRKTREDGGAGSAGCTGAADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQMDLCKNGYVPQFSGLMQPYDDMYAGYPYNNWATKSLTPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMNMPSGMGHSAVPGMANSGLNNINNISGSSLNSAMSSPACPYGPPGSPYSVYRDTCNSSLASLALKSKQHSSFGYSSLQSPGSSLNACQYN
Protein: Cadherin-related family member 3 (Cadherin-like protein 28) (Q6ZTQ4)
Organism: Homo sapiens (Human)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24241537}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Cadherin-23
Sequence:
MQEAIILLALLGAMSGGEALHLILLPATGNVAENSPPGTSVHKFSVKLSASLSPVIPGFPQIVNSNPLTEAFRVNWLSGTYFEVVTTGMEQLDFETGPNIFDLQIYVKDEVGVTDLQVLTVQVTDVNEPPQFQGNLAEGLHLYIVERANPGFIYQVEAFDPEDTSRNIPLSYFLISPPKSFRMSANGTLFSTTELDFEAGHRSFHLIVEVRDSGGLKASTELQVNIVNLNDEVPRFTSPTRVYTVLEELSPGTIVANITAEDPDDEGFPSHLLYSITTVSKYFMINQLTGTIQVAQRIDRDAGELRQNPTISLEVLVKDRPYGGQENRIQITFIVEDVNDNPATCQKFTFSIMVPERTAKGTLLLDLNKFCFDDDSEAPNNRFNFTMPSGVGSGSRFLQDPAGSGKIVLIGDLDYENPSNLAAGNKYTVIIQVQDVAPPYYKNNVYVYILTSPENEFPLIFDRPSYVFDVSERRPARTRVGQVRATDKDLPQSSLLYSISTGGASLQYPNVFWINPKTGELQLVTKVDCETTPIYILRIQATNNEDTSSVTVTVNILEENDEKPICTPNSYFLALPVDLKVGTNIQNFKLTCTDLDSSPRSFRYSIGPGNVNNHFTFSPNAGSNVTRLLLTSRFDYAGGFDKIWDYKLLVYVTDDNLMSDRKKAEALVETGTVTLSIKVIPHPTTIITTTPRPRVTYQVLRKNVYSPSAWYVPFVITLGSILLLGLLVYLVVLLAKAIHRHCPCKTGKNKEPLTKKGETKTAERDVVVETIQMNTIFDGEAIDPVTGETYEFNSKTGARKWKDPLTQMPKWKESSHQGAAPRRVTAGEGMGSLRSANWEEDELSGKAWAEDAGLGSRNEGGKLGNPKNRNPAFMNRAYPKPHPGK
Protein: Uncharacterized protein (Q57XN5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MYRPRGGAKQDRKESAASRKADHSGSQTSDATSPDVSFVNSIVGLKTRLLTPFMKYDKTLKQVVINPEHDRVFRSEVSRVQGVVLRELRRILEFDSRLTPKEALYLVQKSVMLAFASCAVGSDGEVLVPCGSDEEAEVFMPRLEKIFAERSACAKAVVSLTAVLCTGVVRDNYGVVCQRLEARLAAEEASPANSRRTDVELQALAATKKNTQDFLQFRAALVTAFDSISAPLTSNGSNSIPRETAAADGTTANLVVQSFYSLLGWMLMVQPDRLNLETTRITPSLPFPPQDISDPPVTVTYYDPSSGKITIERSASSFKWGLLINMASKLIGVENTLRTATSTGGELFHALQLSEGGLPIYNINGVTIREPGEQEADGDVSEEVRVSRLEKLQNILKSKVTKVSLLVAGVSGMHDPQEVSFNIIPQGGEGASGQEACLILKRPSVSVDWKLKLVANGENQLILDSVSPNISLSNAASEFINTHLGNLHVAQVNGCEPKNNSFLDDVMRSSLFLILRLQTVATVNSDSKDGSVAVGVGNSRRQPKAMEIEKLEGAELAERGGSKSNVMRSAADDEIKNAGNLDSQHRHGTDSDRPLPEGQGTREQGDEETQHEGSEKTEPKKRGRRRKTLHSSETDDRTAETSGEVRSSTVATKETKKVGTTEGEEKGEATKKRKAEKKASEKKKKDKEDARKKAGKKLSKAAKKSGKEKKGGKTKKGKDKEEGEEKRTRGRKSNKAKDSESKDGEAKEETPEGGKKADSGAGTSLKEAAEAQGVVDKPLVDVKPRSDAAVVVSRKSESKKESSSSTSPGGGDAAAVRIAVAPKGSVAMTPEVMAELKEAPPLTFENAVTLDHFDGMNMELRRPDLKTSWDISMTHGGDKLVLTRLPPVSAALKTHPFMKTLVPDDAGQISWQVDGVNGIDLHNATKSIRLQAMDSIKKSSKVSLILRQLIK
Protein: chitinase (EC 3.2.1.14) (Q84S31)
Organism: Vitis vinifera (Grape)
Interaction partners:
Sequence:
MARTPQSTPLLISLSVLALLQTSYAGGIAIYWGQNGNEGTLTQTCNTGKYSYVNIAFLNKFGNGQTPEINLAGHCNPASNGCTSVSTGIRNCQNRGIKVMLSIGGGVGSYSLSSSNDAQNVANYLWNNFLGGQSSSRPLGDAVLDGIDFDIELGSTLHWDDLARALSGFSKRGRKVYLTAAPQCPFPDKFLGTALNTGLFDYVWVQFYNNPQCQYSSGNTNNLLNSWNRWTSSINSQIFMGLPASSAAAGSGFIPANVLTSQILPVIKRSPKYGGVMLWSKYYDDQSGYSSSIKSSV