wanglab/gogpt-training-data huggingface dataset:
Protein: Small ribosomal subunit protein mS33 (Q9VEV5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Small ribosomal subunit protein mS31
- GEO10172p1
- Small ribosomal subunit protein mS40
- Mitochondrial ribosomal protein S21, isoform A
- Large ribosomal subunit protein mL66
- Small ribosomal subunit protein uS12m
- GEO07594p1
- Mitochondrial ribosomal protein S23
- Small ribosomal subunit protein uS3m
- GH07821p
Sequence:
MSHKYTELIKVGTQYARRMNYLSNRIFGEVARTTNEKSMKVVRMFSEEPIHKRDYVINWYPRHVETHLLMKNLRDYGLFRDEHQDFKEEMKRLRKLRGKAPPKKGEGKRASKK
Protein: No pollen (Q66VB0)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MTRLRSLSSSARLAAAEWAAPMKLQVRVVEARGLPAVRVDGTSDPFVKLQLGKRRAKTAVARRTLAPAWDEEFSFLVGDIAEELVVSVLNEDKYFSNDLLGKVRVPLADVMETDDLSLGTAWYQLQPKSKKSKKKSRGEVCLCISLSTRTHVSEESQSVNPASDDASSSDRSIEHKDAVLSTTSSYIDLSACASAMDRASQSSMEQLADSIVDQPPRSSMEQLAVAEPGAAAAEGDAMSNSSSVVEVLSRYFFGNKPADVAPSAASDAESVDQFQEPKVCSEDHETPESGTSSESSLDELLKTMESKDQGCEMPANLPGGVLIDESYVAAPTELNSLLFSKNSDFWPAVSELQGTSGFQIEPWKLDNNETCLQRTLTYTKAASKLVKAVKATEEQKYLKAAGNSFAVHSVVSTPDVPCGGCFKIEILYCITPGPSLSSEEQTSHLTVSWRVNFVQSTMMKGMIESGAKQGMAEGFAHFSEILSQKIKVAEADDANSNKEKILSSLHAQKESGWRLIVRFLFNFTFIFSVIIASYVIAHLHLSKPNAMHGLEYFGIDLPDSIGEVVVCAVLILQGQNIFNIIKRFLNAWKQKGSDHGVKAHGDGWLMTVALIEGTGITNSNSKELFDMYAVFTCNAKRKTSSVKFQTSEPKWNEIYEFDAMDDPPSRMDVAIHDANGPFDQSPIGHAEVNFLKSNLSDLTDVWLPLEGKCDQTSNPKIHLRIFLNNSRGTEVVMNYLAKMRKEVGKKINLRSAQTNAAFRKLFNLPPEEFLIDDFTCHLKRKMPLQGRLFFSPRIIGFYSNIFGHKTKFFFLWDDVDDIQVIPPTLSIGSPSLTIILRKGRGLEAKHGAKGTDPNGRLKYYFQSFVSFNDAHRIIMAIWKMRSLSPEQQGDMIEKESDTKELQLEEGGTLFTHEDVKMSEIFSSALSVDVESLMEMFSGGPLEHRMMQKAGCIDYSPTEWELVSRNIYQRQISYKFDKNLSRYGGEATTTQQRYALVNQEGWAIEEVMSLQGVLLGDCFNVQMKYTVVNVPSKPNTCSVQVLLGIAWLKSTKQQKKITKSVISNSSIRLKELFAEVEKDLTSRSGAS
Protein: Protein FDO1 (FKH1-interacting protein involved in donor preference) (P40214)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: In concert with FKH1, plays a role in directionality of mating type switching by controlling which donor mating-type locus is inserted into MAT locus during mating type switching.
Interaction partners:
- Uncharacterized protein YER079W
- Putative uncharacterized protein YOR248W
Sequence:
MEENKLSGNKPIQLATWSNQMGSPENNGNNANNGSDVQNVIQKALGLIRQLNNNGLMSPMEEEHSQPSSSQETLSVDREINEQGRLRLLMQAKDDNTRKEVGTYSSPMDSAYARENMLNVLQSLVTHLNQAVSQIQQLKFKNMILTSNENNIQSRHEVEDNLQKQQFERMKCQFLLERQSLKDQLRKRENKIVKYKQKIIEKNKKLNNLAKVLNQHAISDTSQIDSFSSSVKKTPSSTTTPQEMKSDMLNTLGILATHVLKDEIDDDSGNQTILQLAAGSISNDCNTTELEITCSPEMGRTITHNRPNTKDESIQDSHGNRTLQLPKMKSFSTIDGSIKDIK
Protein: Rho-associated protein kinase (EC 2.7.11.1) (A0A2P9DU05)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS
Protein: RNA-binding protein 20 (RNA-binding motif protein 20) (E9PT37)
Organism: Rattus norvegicus (Rat)
Function: RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes encoding key structural proteins involved in cardiac development, such as TTN (Titin), CACNA1C, CAMK2D or PDLIM5/ENH. Acts as a repressor of mRNA splicing: specifically binds the 5'UCUU-3' motif that is predominantly found within intronic sequences of pre-mRNAs, leading to the exclusion of specific exons in target transcripts. RBM20-mediated exon skipping is hormone-dependent and is essential for TTN isoform transition in both cardiac and skeletal muscles. RBM20-mediated exon skipping of TTN provides substrates for the formation of circular RNA (circRNAs) from the TTN transcripts (By similarity). Together with RBM24, promotes the expression of short isoforms of PDLIM5/ENH in cardiomyocytes.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00130, ECO:0000269|PubMed:23307558, ECO:0000269|PubMed:35394688}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000269|PubMed:35394688}. Note=The active form that regulates alternative splicing localizes to the nucleus (PubMed:35394688). Also localizes to cytoplasmic ribonucleoprotein granules; localization to cytoplasmic ribonucleoprotein granules plays an important regulatory role (By similarity). Subcellular localization is regulated by phosphorylation of different parts of the protein: while phosphorylation of the RS (arginine/serine-rich) region promotes nuclear localization, phosphorylation of the C-terminal disordered region promotes localization to cytoplasmic ribonucleoprotein granules (PubMed:35394688). {ECO:0000250|UniProtKB:Q5T481, ECO:0000269|PubMed:35394688}.
Interaction partners:
- Titin
Sequence:
MVLAAAMSQDADPSGPEQPDRDACIVPGVQGPPAPQGQQGMQPLPPPLPPPPQPQSSLPQIIQNAAKLLDKNPFSVSSQNPLLTSPASVQLAQIQAQLTLHRLKMAQTAVTNNTAAATVLNQVLSKVAMSQPLFNQLRHPSVLGTTHGPTGVSQHAATVPSAHFPSTAIAFSPPSQAGGPGPSVSLPSQPPNAMVVHTFSGVVPQTPAQPAVILSIGKAGPTPATTGFYDYGKANPGQAYGSETEGQPGFLPASASAAASGGVTYEGHYSHTGQDGQATFSKDFYGPSAQGSHAAGGFPADQAGSMKGDVGGLLQGTNSQWERPSGFSGQNKADITAGPGLWAPPASQPYELYDPEEPTSDRAPPAFGSRLNNSKQGFNCSCRRTKEGQAMLSVRPLQGHQLNDFRGLAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKCLLFSESAGLRSICATGEGTLSASANSTAVYNPTGNEDYTSTLGTSYAAIPTRAFAQSNPMFPSASSGTNFAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKPALINGEKLLIRMSTRYKELQLKKPGKNVAAIIQDIHSQRERCMLREADRYGPERPRSRSPMSRSLSPRSHSPPGPSRADWGNGRDSYAWRDEDRETVPRRENGEDKRDRLDVWAHDRKHYPRQLDKAELDERLEGGRGYREKYLKSGSPGPLHSASGYKGREDGYHRKETKAKLDKHPKQQQQDVPGRSRRKEEARLREPRHPHPEDSGKEEDLEPKVTRAPEGTKSKQSEKSKTKRADRDQEGADDKKEGRGAENEAGTEEQEGMEESPASVGTQQEGTESSDPENTRTKKGQDCDSGSEPEGDNWYPTNMEELVTVDEVGEEDFIMEPDIPELEEIVPIDQKDKILPEICPCVTATLGLDLAKDFTKQGETLGNGDAELSPKLPGQVPSTSTSCPNDTDMEMAGLNLDAERKPAESETGLSPEVSNCYEKEARGAEGSDVRLAPAAQRMSSPQPADERAQQSSPFLDDCKARGSPEDGPHEVSPLEEKASPTTESDLQSQACQENSRYTETRSLNSRSPEFTEAELKEPLSLPSWEPEVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSEEAAKVSHCRSTVHYRNLQKYLSQLAEEGLKETEGVDSPSPERSGIGPHLERKKL
Protein: Protein DMP2 (AtDMP2) (Q9LVF1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in membrane remodeling.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20712629}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000269|PubMed:20712629}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- UPF0496 protein At3g49070
- Plant self-incompatibility protein S1 family
- Glycine-rich protein homolog
- STAY-GREEN-like protein
- Uncharacterized protein
- Transmembrane protein
- Uncharacterized protein
- Uncharacterized protein
- Non-LTR retroelement reverse transcriptase
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
Sequence:
MSKTFKAIRDRTYSGVGDLIKLLPTGTVFLFQFLNPVLTNNGHCLLINKYLTGVLIVICAFSCCFTCFTDSYRTRDGYVHYGVATVKGLWPDSSSVDLSSKRLRVGDFVHAFFSLIVFSVISLLDANTVNCFYPGFGSAGKIFLMVLPPVIGVISGAVFTVFPSRRHGIGNPSDHSEDDASEMK
Protein: Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) (Q57W99)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion {ECO:0000256|HAMAP-Rule:MF_03135}.
Interaction partners:
- Elongation factor TU, putative
- Small ribosomal subunit protein uS5
- Ribosomal protein
- 40S ribosomal protein S14
- 60S ribosomal protein L17, putative
- Large ribosomal subunit protein uL5
- 40S ribosomal protein S15, putative
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S23, putative
- 50S ribosomal protein L17, putative
Sequence:
MLFRTIRHFDLRRPTLMELVRELRFRTEAPIADCCAALKEANENMDRALEVLRNKGLAKAVKKGSRVTEHGSVVACVGETFGAAIVTVCSETDFAARSLQFQRVCGTVMETLRTQIISTEGTALDDCAAVHRLLTDAAAEQIQATIAVLGENVTIKSIQPLRFAPHVAEHISIGAYTHGTLSVQNVGRVAGVVAVSRTDPSARVPEEKLVDVARHFVACSGAEGSYAHQNFFGTEETVGQWLKRHGLRFSSSLVVDFGKEPIIHTAPQPVAGTK
Protein: Ribosomal RNA-processing protein 40 (Q93830)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- Putative exosome complex component RRP41
- Exosome complex component RRP45
- Ribosomal RNA-processing protein 42
- Exoribonuclease phosphorolytic domain-containing protein
- Exosome complex component RRP46 homolog
- Exosome complex component CSL4 homolog
- Exosome complex component RRP4 homolog
- Ribosomal RNA-processing protein 43
- Exosome complex component 10 homolog
- Probable exosome complex exonuclease RRP44
Sequence:
MTVYLPGDVINEPSSSDSSIIGYGISVRGQTRIATQPGAFHNDDGKVWLNVHSKRYIPQEGDRVIAIVTSKTGDFFRLDIGTAEYAMINFTNFEGATKRNRPNLKTGDIIYATVFDTTPRTEAELTCVDDEKRARGMGQLNGGFMFKVSLNHCRRLINPSCKILQTVGKFFKFEITVGMNGRIWISASTSDDIIKIHDIINKSEFITDEDELITLVQNNYTRSVSD
Protein: UDP-glycosyltransferase 87A2 (EC 2.4.1.-) (O64733)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- F23A5.30 protein
- Pathogen-associated molecular patterns-induced protein A70
Sequence:
MDPNESPPNQFRHVVAMPYPGRGHINPMMNLCKRLVRRYPNLHVTFVVTEEWLGFIGPDPKPDRIHFSTLPNLIPSELVRAKDFIGFIDAVYTRLEEPFEKLLDSLNSPPPSVIFADTYVIWAVRVGRKRNIPVVSLWTMSATILSFFLHSDLLISHGHALFEPSEEEVVDYVPGLSPTKLRDLPPIFDGYSDRVFKTAKLCFDELPGARSLLFTTAYELEHKAIDAFTSKLDIPVYAIGPLIPFEELSVQNDNKEPNYIQWLEEQPEGSVLYISQGSFLSVSEAQMEEIVKGLRESGVRFLWVARGGELKLKEALEGSLGVVVSWCDQLRVLCHKAVGGFWTHCGFNSTLEGIYSGVPMLAFPLFWDQILNAKMIVEDWRVGMRIERTKKNELLIGREEIKEVVKRFMDRESEEGKEMRRRACDLSEISRGAVAKSGSSNVNIDEFVRHITNTN
Protein: Sperm protamine R3 isoform 2 (P83267)
Organism: Hydrolagus colliei (Spotted ratfish) (Chimaera colliei)
Function: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:8875866}. Chromosome {ECO:0000269|PubMed:8875866}.
Interaction partners:
Sequence:
ARRRHSMKKKRKSVRRRKTRKNQRKRKNSLGRSFKAHGFLKQPPRFRP
Protein: Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6) (P60662)
Organism: Sus scrofa (Pig)
Function: Regulatory light chain of myosin. Does not bind calcium.
Interaction partners:
- Myosin regulatory light polypeptide 9
- Myosin-2
- Myosin-11
- Myosin regulatory light chain 12A isoform 2
- Myosin-4
- Myosin-10
- Myosin heavy chain 13
- Myosin heavy chain 3
- Myosin heavy chain 7B
- Myosin-7
Sequence:
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG
Protein: Paired mesoderm homeobox protein 1a (Paired related homeobox 1) (Paired-related homeobox 1a) (Prrx1 protein) (Q7T373)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Zinc finger homeobox 3.
- Transcription factor twist1
- Heart- and neural crest derivatives-expressed protein 2
Sequence:
MTSSYAHVMDRQATLPNRLETAITANQDHLQAKKNFSVSHLLDLEEAREMVGAQAEESAGEAGRSMLESPGLTSGSDTTQQENEQLNAEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLASKNASLLKSFSGEVTAVEQPIVPRPAPRPNDYLSWGSSPSYSAMATYSPSCANNTTAQGMNMANSIANLRLKAKEYSLNQVPTVN
Protein: RE17417p (Q9VW19)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKAFLWALVILLGYIPQSTIAKTVSTDFLDLLDFSDNDEFQWGESENQVYENRTGENRVVSFLSQHRLNKRQAPTSQLLENKDYGACSTPLGESGRCRHIIYCRMPELKNDVWRLVSQLCIIEKSSIGICCTDQSTSNRFSPQVVTSADGDEPRIVNKPEQRGCGITSRQFPRLTGGRPAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHCIYKKNKEDIFVRLGEYNTHMLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPPVNEDWSDRNAIVTGWGTQKFGGPHSNILMEVNLPVWKQSDCRSSFVQHVPDTAMCAGFPEGGQDSCQGDSGGPLLVQLPNQRWVTIGIVSWGVGCGQRGRPGIYTRVDRYLDWILANADV
Protein: Casein kinase I (PfCK1) (EC 2.7.11.1) (O15726)
Organism: Plasmodium falciparum (isolate Dd2)
Function: Serine/threonine-protein kinase likely to be involved in many cellular processes. Phosphorylates rhoptry protein RON3, nucleosome assembly protein NAPL and DNA/RNA-binding protein ALBA4 in vitro (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8IHZ9}. Cytoplasmic vesicle, secretory vesicle, microneme {ECO:0000250|UniProtKB:Q8IHZ9}. Secreted {ECO:0000250|UniProtKB:Q8IHZ9}. Host cell surface {ECO:0000250|UniProtKB:Q8IHZ9}. Note=At the ring and early trophozoite stages, localizes to the host erythrocyte cell surface. In mature trophozoites, localizes to the parasite cytoplasm. At the segmented schizont stage, localizes to a single dot, probably micronemes, in each merozoite. {ECO:0000250|UniProtKB:Q8IHZ9}.
Interaction partners:
Sequence:
MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVRMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTSYPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVLCRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWTCVYASEKDKKKMLENKNRFDQTADQEGRDQRNN
Protein: Dipeptidyl-peptidase 7 (DPP7) (EC 3.4.14.-) (C2M262)
Organism: Capnocytophaga gingivalis
Function: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Most potently cleaves the synthetic substrate Met-Leu-methylcoumaryl-7-amide (Met-Leu-MCA), followed by Lys-Ala-, Leu-Arg- > Leu-Asp-, Leu-Glu-, >Leu-Lys, and >Val-Arg-MCA, while this enzyme does not hydrolyze Gly-Arg-, Gly-Gly-, Lys-Lys-, or Gly-Pro-MCA.
Interaction partners:
Sequence:
MRKLIFSLVTSFFLLLPSVIRADEGMWFLMFIKRLNERDMQKKGLQLTAEEIYSINNNSLKNAIVQFNGGCTASIISPDGLVITNHHCGYGAIAGLSTPEHNYLKDGYWAKDRSQELPPKSLYVRFFVRMDNVTDRMLSVVNSSMSEKERQDALNREMEKIQKENSEGGKYVVSVRPFFQGNEYYYFVYQDFKDVRFVGTPPENVGKFGGDTDNWEWPRHTGDFSVFRVYTDKDGNPAPYSPNNIPMKAKKYLNVTLKGVQENDFAMILGYPGRTNRWVSSHWVDQQVKYGYPAWVEASKTAMDAMKAHMDKDKAVRLKYASRYASLANYWKNRQGMIDALTAHKTADLKRAAEKKFAVWANKPENKAEYGNVLSDLATYFEKTNQEAANHNYLLLFFRASRIVPQANGYVKQLNTYLNSSSDQEKQQIRERIAKELDAYYSESYLPAEIDLFADNLKLYADKATDIPQEIAQIKSQYNGDFRKFAAEVFARSIFTTKENFENFMNNPSSDALQSDPIAQIARVMIDKYYNSQSEALKDGYEKAFRKYVKGMRDSKVSLILYPDANSTLRLTYGSVKSLPKDKRNHDVKRNYYTTFKTMLEKYKPGDAEFDMPKKFVEMYEKKDFGRYLDKDGTMHVCFLTNNDITGGNSGSPVMNGKGELIGLAFDGNIEAMAGDVIFDKKLQRTIVVDIRYVLWCIDTFGGAKHIVDEMTIIQ
Protein: Adenylate cyclase type 5 (EC 4.6.1.1) (ATP pyrophosphate-lyase 5) (Adenylate cyclase type V) (Adenylyl cyclase 5) (Q04400)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P30803}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P30803}. Cell projection, cilium {ECO:0000250|UniProtKB:P84309}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- Guanine nucleotide-binding protein G
- Rap guanine nucleotide exchange factor 3
- Guanine nucleotide-binding protein G
- Adenylate cyclase type 6
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Rap guanine nucleotide exchange factor 4
Sequence:
MSGSKSVSPPGYAAQTAASPAPRGGPEHRAAWGEADSRANGYPHAPGGSTRGSTKRSGGAVTPQQQQRLASRWRGGDDDEDPPLSGDDPLVGGFGFSFRSKSAWQERGGDDGGRGSRRQRRGAAGGGSTRAPPAGGSGSSAAAAAAAGGTEVRPRSVEVGLEERRGKGRAAEELEPGTGTVEDGDGSEDGGSSVASGSGTGTVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLQVVYLAVLAAAVGVILIMAVLCNRAAFHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAISLHTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISSVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHSLFMLSFYLSCFLLLALVVFISVIYACVKLFPTPLQTLSRKIVRSKKNSTLVGVFTITLVFLSAFVNMFMCNSKNLVGCLAEEHNITVNQVNACHVMESAFNYSLGDEQGFCGSPQSNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADLLVTANAIDFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKAGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
Protein: Ribosome assembly protein METTL17, mitochondrial (Methyltransferase-like protein 17) (Q3U2U7)
Organism: Mus musculus (Mouse)
Function: Probable S-adenosyl-L-methionine-dependent RNA methyltransferase required to stabilize the mitochondrial small ribosomal subunit (mt-SSU). Required for protein translation in mitochondria.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:31487196}.
Interaction partners:
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS12m
- Dimethyladenosine transferase 1, mitochondrial
- Small ribosomal subunit protein uS11m
Sequence:
MATARTPRFLLLFCRSCRSLRGPQSRAYAALVPGVSQVDNGSDFLGKKPHRKHPGILHLPHVQLPQALADAAQLMLFERPMRSVEKQVQALTNYLWSRHLPVEPEELQRRAAYLEKKFLEKQDSAPTEEKLREAVLHALRKTTYHWQELSYSEELSLIYMAARLDGGFAAVFRAFHEIQARIPEFRPQTLMDFGSGTGSVAWAAHRTWGQSLREYVCVDSSAAMLGLAEKLLKGGSESGKPCIPGVFFRQFLPVSPKVQFDVVVSAYALSELPSRADRIEVIQNLWRKTSHFLVLVENGTKAGHRLLMDARNLVLGEKEKSPLDLRPSFVFAPCPHELPCPQLNASKSLACSFSQAYHPIPFNWNKKPKEEIFSMVILARGSPKEANRWPRITQPVLKRPRHVHCHLCCPDGHMQHAVVTARRHGRDLYRCARVSSWGDLLPVIAPSEFPPSSPDEEPPEN
Protein: SMP-LTD domain-containing protein (A0A1D8PNV5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}.
Interaction partners:
Sequence:
MGLVYFLFVYVLGGLTFLPGLVALYFYLAPKSTLSDDNELDEEKPSGELEEKHQSGLEAYKSGWIFVTRDYIESPDEINSNTQSITESNDNKSAYSALYKLVKDSATKKFKDNSQSKKLQPEEKKFLDHDDNDLDELNKDTFALPKDTNSPNPKSYSHHQRHDPQPQHNHQSQNQPQQQIRSSQKKHRYFAVLKHGNLFLYKDQTLKDVKHVIVLAHHFVSIWPRDLTDAQLFTKYSALALINPSKLTDTPFSTNDTFNSTVNTSNGTEISSSTRSSLSSRTTDQQQNSQQQTNNNAPPGTFFIYCENNCDKEDWYFALIRAMKLEKSELPDILNPEKYAETSHFQTKEMINLIQTLYSSEGQLQTKWLNAIIGRWFLAMKNTKHFEDYVYKKLSKKLNKIKKPGFFNQFEITDIQPGKSAPFFTYPKLKEINPDGTVVASCYVTYNGGLSVTIETKVDLTFGTKFTNREVDLVLKITLSKLEGPMLFKLKPPPSGRFWYCYELDPIVNFKIEPLLSSRTLNFNFITNSIEKKFKEAIKESLVYPFWDDIVFFDSSDQLYRAGIWKEPKIDKDETTASEKENTENNQTDNESAGVDEDNSTNKFDDIDAKSELSTSSRSLRNGKFSNTLTDLTKRMKKKSSPSLSNTEDSLSVNTNNTASLSASSATLNKTPSKSDLTASQSPNTNSTLVSSTFKKIGKWYFKDDGSSKKQHDEKLGYTPPEMISSRRAPRKSSSSMTLGSDSTRYTLATEDNKDLPDIESANSTSASVSNTATTAPSSELSNKGTTTTAPVNVISLSNNSTIPSVAVGADATTTAPAPVANSKLTSTPLDNQTPSYNFSRLDNNNEDLSIFSVAYQNAAQIIPSSTPPPLPPRDISDNLSIRSGSLVGEPTISLSQPNSPIRTKTLTRKPPPPKSPLLHAHSPNQDIKDL
Protein: Large ribosomal subunit protein bL34 (50S ribosomal protein L34) (P0A7P5)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Ribonuclease P protein component
- Large ribosomal subunit protein bL28
- Large ribosomal subunit protein uL11
- Large ribosomal subunit protein uL10
- GTP pyrophosphokinase
- Alternative ribosome-rescue factor A
- Elongation factor Tu 1
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein bL21
- Small ribosomal subunit protein bS16
Sequence:
MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
Protein: Zinc finger and SCAN domain-containing protein 26 (Protein SRE-ZBP) (Zinc finger protein 187) (Q16670)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187, ECO:0000269|PubMed:1569959}.
Interaction partners:
Sequence:
MATALVSAHSLAPLNLKKEGLRVVREDHYSTWEQGFKLQGNSKGLGQEPLCKQFRQLRYEETTGPREALSRLRELCQQWLQPETHTKEQILELLVLEQFLIILPKELQARVQEHHPESREDVVVVLEDLQLDLGETGQQDPDQPKKQKILVEEMAPLKGVQEQQVRHECEVTKPEKEKGEETRIENGKLIVVTDSCGRVESSGKISEPMEAHNEGSNLERHQAKPKEKIEYKCSEREQRFIQHLDLIEHASTHTGKKLCESDVCQSSSLTGHKKVLSREKGHQCHECGKAFQRSSHLVRHQKIHLGEKPYQCNECGKVFSQNAGLLEHLRIHTGEKPYLCIHCGKNFRRSSHLNRHQRIHSQEEPCECKECGKTFSQALLLTHHQRIHSHSKSHQCNECGKAFSLTSDLIRHHRIHTGEKPFKCNICQKAFRLNSHLAQHVRIHNEEKPYQCSECGEAFRQRSGLFQHQRYHHKDKLA
Protein: Myo-inositol transporter 1 (A0A1D8PH98)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Major transporter for myo-inositol.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P30605}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Inositol-3-phosphate synthase
Sequence:
MGSSTNNTQSKATPSVLENEVNSSKSSVVSSTSSAKGLLRETTNHGTMETSSVQISESESRPSKMVLVLTLASSISGFMFGYDTGYISSALVQIGTDLSNKILTSGEKEFITSATSLGALLGAVVGGVLANLIGRRRVLLGSNIIFVVGTIIQLAARTVWTMIAGRFVLGWGVGIASLIAPLMISELAPAKYRGRLIVTNVIFITGGQLIAYFINWGLTRVSHGWRVSVGLCMVPPVLQFVLFWFLPDTPRFYVMNGNFEKARQVLRKVHVDPSDEFVNATIDEMIASDSTVPGNGPLQKAWKSIKIIHTTPGNFRALILACGLQGIQQFTGFNSLMYFSATIFETIGFHNATAVSIIIAATNFVFTGIAICIIDKVGRRRILLVGMPCMCISLIVCAVAFHYLNVDFSTGTVVSRGINGWGIVVIIGMILYVASYAIGIGNAAWVGVELFSDVNVRSIGAMYAACTNWAGSLVIASTFLTMLENITPTGTFSFFAGLCFIAFFFVYFLLPDTAGLELEETTDFLSNGFNVKQAAQLSKERKKHSKFAKSKPTV
Protein: Uncharacterized protein C26H8.11c (O74793)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Adenylyl-sulfate kinase
Sequence:
MPETKLVALPEFQELKSNDEYISMQPYKGEDNKSYIANLVRHNALTFCPYYFIEKSGKGSVVYFHPTSDLCGYKNIVHGGFITTMLDEALAFGVFPNFPSKMGVTVQLDTTYVAPALCSHLYKIVTKTTKVEGRKCWTSGELLRLNGSEPPVLCAKASGFFVEPSKLNLEHHVKK
Protein: Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3) (H0Y871)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYYYPPFDKSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS