wanglab/gogpt-training-data huggingface dataset:
Protein: PTB-containing, cubilin and LRP1-interacting protein (P-CLI1) (Phosphotyrosine interaction domain-containing protein 1) (Q3UBG2)
Organism: Mus musculus (Mouse)
Function: Increases proliferation of preadipocytes without affecting adipocytic differentiation.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MWQPATERLQHFQTMLKSKLNVLTLKKEPIPAVLFHEPEAIELCTTTPLMKARTHSGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVQCESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRSSSSEEASQELESDDG
Protein: Glucocorticoid receptor (Nuclear receptor subfamily 3 group C member 1) (Q38HX7)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MDSKELLKSSDQDETRKNALMSTKGGIVMDFHPPFRGGASAQAPVSAAPLPVSSQSDSAQQPALADFSKGLVNNVPPPDLSKAVSLSMGLYMGETDAKVMGNDLGFSQQGQTGISSGETDFRLLEESIASLNKSSSLAEDAKGAVSSEAPLEPDFVGMAGRGPLEPGASVQSQVGSNGGSLKLSSEDQSTLDILQDLELPSVSPGKEPNGSPWRLDPLLDDGGLLSPISADDTFLLEGNLGEDCKPPILSDTKPKINDRGDLLPSSKMPMPQVKTEKEDFIELCTPGIKQENVGPIYCQANFSGSNMLGTKVSAISIHGVSTSGGQMYHYDLNTASLSQQQDQKPIFNIIPSLPAGSENWNRCQGSGDEALAPLGTLNLSGRPAFSNGYSSPGLRSDVSSSPSTTSATAGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQTTATGTREAAEAAGNKSVVPASLPQLTPTLVSLLEVIEPEVLYSGYDSTLPDSSWRIMSTLNMLGGRQVVAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYKQSNGNLLCFAPDLIINEQRMNLPCMYEQCKHMLMVARELSRLQVSYEEYLCMKTLLLLSTIPKEGLKSQTLFEEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSFCFQTFLDKSMSIEFPEMLAEIISNQIPKYSNGNIKKLLFHQK
Protein: Ubiquitin domain-containing protein DSK2 (P48510)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved, with RAD23 in spindle pole body duplication. Involved in the ubiquitin-proteasome proteolytic pathway.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- E4 ubiquitin-protein ligase UFD2
- 26S proteasome regulatory subunit RPN10
- Polyubiquitin
- UV excision repair protein RAD23
- 26S proteasome regulatory subunit RPN1
- Ubiquitin-ribosomal protein eL40A fusion protein
- Ubiquitin carboxyl-terminal hydrolase RPN11
- 26S proteasome regulatory subunit RPN13
- 26S proteasome regulatory subunit 7 homolog
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MSLNIHIKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLVKSQPKPQTASAAGANNATATGAAAGTGATPNMSSGQSAGFNPLADLTSARYAGYLNMPSADMFGPDGGALNNDSNNQDELLRMMENPIFQSQMNEMLSNPQMLDFMIQSNPQLQAMGPQARQMLQSPMFRQMLTNPDMIRQSMQFARMMDPNAGMGSAGGAASAFPAPGGDAPEEGSNTNTTSSSNTGNNAGTNAGTNAGANTAANPFASLLNPALNPFANAGNAASTGMPAFDPALLASMFQPPVQASQAEDTRPPEERYEHQLRQLNDMGFFDFDRNVAALRRSGGSVQGALDSLLNGDV
Protein: Pleckstrin homology domain-containing family S member 1 (PH domain-containing family S member 1) (Epididymis luminal protein 185) (hEL185) (Q5SXH7)
Organism: Homo sapiens (Human)
Interaction partners:
- WD repeat-containing protein 74
Sequence:
MAGGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIETDGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWCLSPADVEAQTTNDQKGNIPDESQVEKLNVFLSPPDVINYLALTEATGRICVSQWEGPPRLGCIFCHGDHLLAVNDLKPQSLEEVSLFLTRSIQKEDSFRILSYQVAFGEGTELRDRAPGFRTSDRHDVAKRACMESDWCRDSKTAPSTNLCLSFLFCKIMTNDGAGCWIIK
Protein: Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1) (Q5PQ53)
Organism: Xenopus laevis (African clawed frog)
Function: Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. Acts as a negative regulator of ER-Golgi transport (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9UBV8}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q641Z8}. Membrane {ECO:0000250|UniProtKB:Q9UBV8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UBV8}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:Q9UBV8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UBV8}.
Interaction partners:
Sequence:
MASYPYGQGYHGAAGQPPGAPQTNYYGGQQYGGGVQPAASYGRPAPGAPYGSPPSGGVYGHPVPGSAAPGAPGGPYGGQAPGGPYSVPGSTPYGSQQHGSYGQGAPAGNIPPGVDPEAFSWFQTVDTDHSGYISLKELKQALVNTNWSSFNDETCTMMMNMFDKSNSGRIDMFGFSALWRFIQQWRNLFQQYDRDRSGSINQGELHQALCQMGYQLSPQFVQIVMSRYAQRSAQPGLQLDRFIQICTQLQSMTEAFREKDTGQIGTAKLSYEDFITMTTTRLL
Protein: E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2) (A0A0G2JVC1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
Interaction partners:
- Protein Mdm4
- Cellular tumor antigen p53
- Ubiquitin carboxyl-terminal hydrolase 7
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL18
- Androgen receptor
- Tumor suppressor ARF
- Serine-protein kinase ATM
- Tumor protein p73
- RAC-alpha serine/threonine-protein kinase
Sequence:
MKEIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAMIYRNLVVVSQQDSGTSPSESRCQPEGGSDLKDPVQASQEEKPSSSDVVSRPSTSSRRRAISETEENTDELPGERQRKRHRALSFDESLGLCVLREICCERSSSSEATDTPSHQDLDDGVSDHSADCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQAGESDADSFEGDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPDDKGKDKVEISEKAKLESSDQAEEGLDVPDGKKVTEDDAKESSAEDSEEKVAQMLLSQESDDYSQPSTSSSIVYSSQESGKELKEDTQDKEESMESSFSLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN
Protein: Interleukin-1 receptor-like 2 (EC 3.2.2.6) (IL-36 receptor) (Interleukin-1 receptor-related protein 2) (IL-1Rrp2) (IL1R-rp2) (Q9ERS7)
Organism: Mus musculus (Mouse)
Function: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Interleukin-36 receptor antagonist protein
- Interleukin-36 alpha
- Interleukin-36 beta
- Interleukin-36 gamma
- Interleukin-1 family member 10
- Interleukin-1 receptor accessory protein
- Interleukin-1 beta
- Interleukin-1 receptor antagonist protein
- Interleukin-1 alpha
Sequence:
MGVTSLLFCGVFFLLLLFVAADTCEDIFMHNVIISEGQPFPFNCTYPPETNGAVNLTWYKTPSKSPVSNNRHLRVHQDQTWILFLPLTLEDSGIYQCVIRNAHNCYQIAVNLTVLKNHWCDSSMEGSPVNSPDVYQQILPIGKSGSLNCHLYFPESCALDSIKWYKGCEEIKAGKKYSPSGAKLLVNNVAVEDGGSYACSARLTHLGRHFTIRNYIAVNTKEVEYGRRIPNITYPKNNSIEVPLGSTLIVNCNITDTKENTNLRCWRVNNTLVDDYYKDSKRIQEGIETNVSLRDQIRYTVNITFLKVKMEDYGRPFTCHAGVSAAYIILIYPVPDFRAYLLGGLMAFLLLVVSVLFIYNSFKIDIMLWYRSAFHTAQAPDDEKLYDAYVLYPKYPRGSQGHDVDTLVLKILPEVLEKQCGYKLFIFGRDEFPGQAVASVIDENIKLCRRLMVFVAPESSSFGFLKNLSEEQIAVYNALIQHGMKVILIELEKVKDYSTMPESIQYIRQKHGAIQWDGDFTEQSQCAKTKFWKKVRYHMPPRRYPASSPVQLLGHIPCNCKAGKCNAATGLITP
Protein: Major curlin subunit (P28307)
Organism: Escherichia coli (strain K12)
Function: Curlin is the structural subunit of the curli fimbriae. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin.
Subcellular location: Fimbrium. Note=Part of the curli surface structure.
Interaction partners:
- Minor curlin subunit
- Curli production assembly/transport component CsgG
- Curli production assembly/transport component CsgF
- Curli assembly protein CsgC
- Curli production assembly/transport component CsgE
- CsgBAC operon transcriptional regulatory protein
- Uncharacterized fimbrial-like protein SfmH
- Type 1 fimbrin D-mannose specific adhesin
- Probable diguanylate cyclase DgcC
- Cellulose synthase catalytic subunit
Sequence:
MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSELNIYQYGGGNSALALQTDARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSATLDQWNGKNSEMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY
Protein: Endothelial transcription factor GATA-2a (GATA-binding protein 2a) (Q7T3G1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Rhombotin-2
- Runt-related transcription factor
- T-cell acute lymphocytic leukemia protein 1 homolog
- LIM domain-binding protein 1-A.
- SI:bY184L24.2.1
- ETS variant transcription factor 2
- Zinc finger protein ZFPM1
- Growth factor-independent 1A transcription repressor b.
- LIM domain-binding protein 1-A
- BHLH domain-containing protein.
Sequence:
MEVAADQSRWMAHHHAVLNGQHPESHHHGLTHNYMEPMAPLLPPDEVDVFLNHLDSQGNPYYSNSRARVSYGQAHARLTGSQVCRPHLIHSPGIPWLDSGKAALSAAHHNAWAVSHFSKPGLHPASAAYPCSSSSSTAPVSSLTSATHSSPHPLYNFPPTPPKDVSPDPGPSSPTSTTARMDEKESIKYQVSIADGMKMEGCSPLRGSLAMSAQTPSTHHPIPTYPTYSLPAPHDYGGGLFHPGTLLSGSASSFTPKCKSKTRSCSEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNGNGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKRSKRSGEGFEELSKCMQDKTSPFGSASALASHMPHMGHLPPFSHSGHMLPTPTPIHPTFSHPHHSGRSPAWAEPH
Protein: Angiomotin-like protein 1 (Q8IY63)
Organism: Homo sapiens (Human)
Function: Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Subcellular location: Cell junction, tight junction {ECO:0000250}.
Interaction partners:
- Merlin
- RAC-alpha serine/threonine-protein kinase
- Angiomotin
- Multiple PDZ domain protein
- InaD-like protein
- Myc proto-oncogene protein
- Signal transducer and activator of transcription 3
- Transcriptional coactivator YAP1
- Rho GTPase-activating protein 17
- Angiomotin-like protein 2
Sequence:
MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
Protein: Possible osmoprotectant (Glycine betaine/carnitine/choline/L-proline) binding lipoprotein ProX (O69725)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible osmoprotectant transport integral membrane protein ABC transporter ProW
- Possible osmoprotectant transport integral membrane protein ABC transporter ProZ
- ABC-type quaternary amine transporter
- Conserved protein
- Probable lipoprotein LpqZ
- Uncharacterized membrane protein Rv3760
- Probable transmembrane protein
Sequence:
MRMLRRLRRATVAAAVWLATVCLVASCANADPLGSATGSVKSIVVGSGDFPESQVIAEIYAQVLQANGFDVGRRLGIGSRETYILALKDHSIDLVPEYIGNLLLYFQPDATVTMLDAVELELYKRLPGDLSILTPSPASDTDTVTVTAATAARWNLKTIADLAPHSADVKFAAPSAFQTRPSGLPGLRHKYSLDIAPGNFVTINDGGGAVTVRALVEGTATAANLFSTSAAIPQNHLVVLEDPEHNFLAGNIVPLVNSRKKSDHLKDVLDAVSAKLTTAGLAELNAAVSGNSGVDPDQAARKWVRDNGFDHPVRQ
Protein: Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) (P34896)
Organism: Homo sapiens (Human)
Function: Interconversion of serine and glycine.
Subcellular location: Cytoplasm.
Interaction partners:
- C-1-tetrahydrofolate synthase, cytoplasmic
- Trifunctional purine biosynthetic protein adenosine-3
- Bifunctional purine biosynthesis protein ATIC
- Methylenetetrahydrofolate reductase
- Glycine dehydrogenase
- Thymidylate synthase
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase
- Phosphoserine phosphatase
- Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial
- Monofunctional C1-tetrahydrofolate synthase, mitochondrial
Sequence:
MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
Protein: Uncharacterized protein YGR130C (P53278)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Eisosome protein 1
- Eisosome protein SEG1
- Sphingolipid long chain base-responsive protein PIL1
- Sphingolipid long chain base-responsive protein LSP1
- Eisosome protein SEG2
- Meiotic sister-chromatid recombination protein 3
- Protein ISD11
- Polyamine transporter 4
- Uridine permease
- Large ribosomal subunit protein eL39
Sequence:
MLFNINRQEDDPFTQLINQSSANTQNQQAHQQESPYQFLQKVVSNEPKGKEEWVSPFRQDALANRQNNRAYGEDAKNRKFPTVSATSAYSKQQPKDLGYKNIPKNAKRAKDIRFPTYLTQNEERQYQLLTELELKEKHLKYLKKCQKITDLTKDEKDDTDTTTSSSTSTSSSSSSSSSSSSSSSSDEGDVTSTTTSEATEATADTATTTTTTTSTSTTSTSTTNAVENSADEATSVEEEHEDKVSESTSIGKGTADSAQINVAEPISSENGVLEPRTTDQSGGSKSGVVPTDEQKEEKSDVKKVNPPSGEEKKEVEAEGDAEEETEQSSAEESAERTSTPETSEPESEEDESPIDPSKAPKVPFQEPSRKERTGIFALWKSPTSSSTQKSKTAAPSNPVATPENPELIVKTKEHGYLSKAVYDKINYDEKIHQAWLADLRAKEKDKYDAKNKEYKEKLQDLQNQIDEIENSMKAMREETSEKIEVSKNRLVKKIIDVNAEHNNKKLMILKDTENMKNQKLQEKNEVLDKQTNVKSEIDDLNNEKTNVQKEFNDWTTNLSNLSQQLDAQIFKINQINLKQGKVQNEIDNLEKKKEDLVTQTEENKKLHEKNVQVLESVENKEYLPQINDIDNQISSLLNEVTIIKQENANEKTQLSAITKRLEDERRAHEEQLKLEAEERKRKEENLLEKQRQELEEQAHQAQLDHEQQITQVKQTYNDQLTELQDKLATEEKELEAVKRERTRLQAEKAIEEQTRQKNADEALKQEILSRQHKQAEGIHAAENHKIPNDRSQKNTSVLPKDDSLYEYHTEEDVMYA
Protein: tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (Depressed growth-rate protein DEG1) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) (P31115)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Formation of pseudouridines at positions 38 and 39 in the anticodon stem and loop of transfer RNAs.
Subcellular location: Nucleus.
Interaction partners:
- Multisubstrate pseudouridine synthase 7
- tRNA pseudouridine synthase 4
- tRNA
- Elongator complex protein 3
- Ubiquitin-related modifier 1
- tRNA
- Bifunctional protein RIB2
- tRNA
- tRNA pseudouridine
- 21S rRNA pseudouridine
Sequence:
MSNFIRRLVGKMKAISTGTNAIVSKKDSIYANWSKEQLIRRITELENANKPHSEKFQHIEDNKKRKISQEEVTRSKAKKAPKKFDFSKHNTRFIALRFAYLGWNYNGLAVQKEYTPLPTVEGTILEAMNKCKLVPSMVLQDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRDPTNDSREIPYVHVLNQLLPDDIRISAVCLRPPPNFDARFSCVHRHYKYIFNGKNLNIEKMSKAASYFVGERDFRNFCKLDGSKQITNFKRTIISSKILPLSETFYCFDLVGSAFLWHQVRCMMAILFLVGQSLEVPEIVLRLTDIEKTPQRPVYEMANDIPLLLYDCKFPEMDWQEPTVDDYKAIKFTTATEALTLHYELKAAVCNIFKDVLPTANTNNFSKTIINLGDGRGKVVGTYVKLEDRSVMEPVEVVNAKYSKKKNNKNK
Protein: PsqA (Q9V5N1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00320}.
Interaction partners:
Sequence:
MAAVRGHQYFSLRWNNYQNTMTSVFQQLREDLSFVDVTLSCEHGSLKAHKVVLSACSTYFQKLLLENPCKHPTIILPADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLKIKGLCETAENADDLNDAATATITVSENIQQAVVGNIVNAAIVPGAPSPSLEQQQQHHQQQQQQQAQEQHQQQQVHAQQQQQQQQQINAALLTQHGVSSGSVSLSGQLLSSSASGSSGSLAGGQQASQTPSGLQPTPRKSRLKRSKSPDLSSGGGAGSSGGSSSGSTQQQPQPAHHHHPQTILIQGQNPNSIVSLQQTADGNYIPVSGSGDDSDAEDHEHEHNHGHGHGHGGHTHGHGHSHEHSHDHEHEHKPNKICKTEHSVASPASNSSSASNNAAGVSGVTSTGQAIVTQIVVARDGKDTKNMTSLGMGMNGGLLGVPMGFLDFTPEPPAPSATPVTVTEHVDLSCNPSTDTRDLSNTTEPLDIDNHLAQQIHRLDQSPMHSISHHHTGDESNSNLVQHIKSEVIEAKHLAAQHHALSQAQQQHAHHQAHQQHQQHQQQQHQQQQQHLHAQQLLAQSQLQQQQQQQQQQQQHHQQQQQQAAAAAAAAGVHGQHGGHVTHADIGGATVMEIDPSQIKHEPGMIITPEIVNMMSSGHMDMYNSDTSEDSMMIANGSPHDQKEPHYTNLDQQHGLGGSVCGPGPGGAGGGGGMSGGAGSGSGEKGQFNGPKAWTQDDMNSALDALKNQNMSLTKASAIYGIPSTTLWQRAHRMGIETPKKEGGTKSWNEDALQNALEALRSGQISANKASKAFGIPSSTLYKIARREGIRLAAPFNAAPTTWTPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYGRCKREGIELSRSNPTPWSEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYGRFKRGKYDVVANTSGVALLNTSGNTTGSIEIIEHSQENSLHMLQQQFPYSPSPHPPTPQHHSTPQHHSSAQQGPPTPQHMQQHVVHMQQQQQQQQQQQSPHPGHHPQHMQQDVVTSSSQVVHSQQQQQLQQIYQHHGTPERS
Protein: Brain enriched guanylate kinase associated (A0A1B0GVM0)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
Sequence:
MLSGASSQARGSNPTCPRQDGYSSLLEPGTEAPIKEAHRQDLRSHMPSPSQGRNPKGKASCHRWAARSSQEMARVSPAQPSSPESLNTGSRAVTGSLARLGRWREARLPFSRFLDEVTVRVLDPGTLEAFRVPRGRSPEPSAVDRGQGLAQEALTRAAAPGEKDPALSSQLSSEAATEAASRVGPGQAVGTSGPCLGSGKRGGRTASPWRSPGRASAADMEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPTCVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERRRDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSYSSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPLEAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGDDLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQGSRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN
Protein: Receptor-like protein CLAVATA2 (Receptor-like protein 10) (AtRLP10) (O80809)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the perception of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristems maintenance. Required for the sensing of the root CLE peptides (e.g. CLE8, CLE9/CLE10, CLE11, CLE13, CLE14, CLE16, CLE17, CLE18, CLE20, CLE21, CLE25, CLE26, CLE40, CLE41/CLE44 and CLE45), which involves also CRN and leads to root growth regulation, mostly in the phloem and protophloem. Involved in controlling the stem cell population size in shoot and root apical meristems, and during organ development. Promotes the formation of CLV1 multimers. In complex with CRN, perceives secreted CLV3-like effector proteins from plant-parasitic cyst nematodes as ligand mimics of the plant CLE signaling pathway. This recognition is required for proper feeding structure (syncytium) development and ultimately successful nematode infection. CLE14 perception by CLV2/CRN complex triggers root meristem differentiation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19933383, ECO:0000269|PubMed:21051944, ECO:0000269|PubMed:27229734, ECO:0000269|PubMed:28607033}; Single-pass type I membrane protein {ECO:0000269|PubMed:19933383, ECO:0000269|PubMed:21051944}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21051944, ECO:0000269|PubMed:27229734, ECO:0000269|PubMed:28607033}; Single-pass type I membrane protein {ECO:0000269|PubMed:21051944}. Note=Requires CRN for export from the endoplasmic reticulum and localization to the plasma membrane. {ECO:0000269|PubMed:19933383, ECO:0000269|PubMed:27229734, ECO:0000269|PubMed:28607033}.
Interaction partners:
- Protein CLAVATA 3
- Receptor protein kinase CLAVATA1
- Inactive leucine-rich repeat receptor-like protein kinase CORYNE
- Protein WUSCHEL
- CLAVATA3/ESR
- CLAVATA3/ESR
- CLAVATA3/ESR
- LRR receptor-like protein
- CLAVATA3/ESR
- Serine/threonine-protein kinase-like protein ACR4
Sequence:
MIKIADFTLFFFIFVFSPSLPLAQSQLPDLDPQDKASLLIFRVSIHDLNRSLSTWYGSSCSNWTGLACQNPTGKVLSLTLSGLNLSSQIHPSLCKLSSLQSLDLSHNNFSGNIPSCFGSLRNLRTLNLSRNRFVGSIPATFVSLKELREVVLSENRDLGGVVPHWFGNFSMNLERVDFSFCSFVGELPESLLYLKSLKYLNLESNNMTGTLRDFQQPLVVLNLASNQFSGTLPCFYASRPSLSILNIAENSLVGGLPSCLGSLKELSHLNLSFNGFNYEISPRLMFSEKLVMLDLSHNGFSGRLPSRISETTEKLGLVLLDLSHNSFSGDIPLRITELKSLQALRLSHNLLTGDIPARIGNLTYLQVIDLSHNALTGSIPLNIVGCFQLLALMISNNNLSGEIQPELDALDSLKILDISNNHISGEIPLTLAGLKSLEIVDISSNNLSGNLNEAITKWSNLKYLSLARNKFSGTLPSWLFKFDKIQMIDYSSNRFSWFIPDDNLNSTRFKDFQTGGGEGFAEPPGKVEIKISAAVVAKDELSFSYNLLSMVGIDLSDNLLHGEIPEALFRQKNIEYLNLSYNFLEGQLPRLEKLPRLKALDLSHNSLSGQVIGNISAPPGLTLLNLSHNCFSGIITEKEGLGKFPGALAGNPELCVETPGSKCDPANIDASQEEIYQNELVEGPISIWIFCLSAFISFDFGVLGIFCSARARSYILQTKA
Protein: Probable choline transporter (Q9HX83)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- HTH-type transcriptional regulator BetI
- Oxygen-dependent choline dehydrogenase
- NAD/NADP-dependent betaine aldehyde dehydrogenase
- Choline sulfatase
- Probable GMC-type oxidoreductase
Sequence:
MNPPVFYGAAILILLFAAVVIGFPQRAGEWLLAAQTWASQTVGWYYLLAMTLYLIFVVVTALSGYGKIKLGADHDEPEFSYLSWAGMLFAAGISITLFFFCVSEPLTHFLQPPQGEAGTQEAARQAMELLFLHWGLHGWGVFALVAMALAYFAYRHNLPLALRSALYPLIGKRINGPIGYTVDCFGIIATVFGLGADMGFGVLQLNSGLDYLYAIPHTHPVQMALIVLMMGAAISVAVSGVDKGIRILSDINMLLACSLLLFVLFAGPTQHLLNTLVQNVGDYLGHLPGKSFDLYAYGGPSDWLGSWTVFYWAWWIAWAPFVGLFIARISRGRTIREFVFGVLFIPLGFTLAWMSIFGNSALEQALGGASELGRVAIEQPSMALYQMLQNYPWSRAVITVTVLVSFVFFVTSADSGTVVLSTLSAHGGSADDDGPKWLRVFWGSVTALVTGGLLFAGSIDALKSAVVLTSLPFSLILLLMMWGLHKAFYMESQRQRARSHSLAPLMSGNGKRSGGWKRRLSQAVHFPSRDEVYRFMNDVVRPAISEVSEVFREKGLAVDAQLDPGNASLSLEIGHGEQHRFLYQVLMRGYFTPSFARAGMGGLHLKNRRYFRAEVHLAEGSQDYDLMGYTKEQIINDMLDQYERHLQFLHLVR
Protein: Thymine-DNA glycosylase (A0A096MIY3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Growth arrest and DNA damage-inducible protein GADD45 alpha
- Small ubiquitin-related modifier 1
- Single-strand selective monofunctional uracil-DNA glycosylase
- DNA
- Histone lysine acetyltransferase CREBBP
- Adenine DNA glycosylase
- DNA
- Uracil-DNA glycosylase
- DNA repair nuclease/redox regulator APEX1
- Methylcytosine dioxygenase TET
Sequence:
MDAEAARSYSLEQVQALYSFPFQQMMAEAPNMADVAGQQMPAEAPAQDPVPEAPKRRKRKTRAAEAQDPVEPKKPAASKKSGKSTKSKEKQEKITDTFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERSTDVQEVQYTFDLQLAQEDAKRTAVKEEKYDPGYEAAYGGACGENPCNGEPCGFASNGLTANSAELGGESAPSDVPNGQWMAQSFAEQIPSFNNCGTGEQEAGSHAGSHA
Protein: COMPASS component cclA (Q2U741)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Subcellular location: Nucleus {ECO:0000305}. Chromosome, telomere {ECO:0000305}.
Interaction partners:
- Uncharacterized protein
- Histone-lysine N-methyltransferase, H3 lysine-4 specific
- Mitochondrial division protein 1
- Uncharacterized protein
- Histone H4
- Peptidase family M20/M25/M40 protein
- Uncharacterized protein
- Histone H3
- Histone H3
- Histone H2A
Sequence:
MASIQPAGSSAPSSNINSPILPPSGTPFFNGPLSDTNTRSSPAPASNASAQTDGPRSKRNKRDSRKKREAKGLDQEIVPAKKRATAVQNTALPSSDLNILRPLLLAEPRPSDLLPPQPRQLNLVSRKTSEVIGQSWSFYEVVDKLTNKNGFRYSYAIADTSFPHIKYRQTDVRPYNARFSFEDSPAAILFNEDALAVTTNGPWHTARANVCAREGTFYYEARIISGVLSDPQTAPANGKSCLPSRGHVRLGFARREADLDVNVGVDCYGYGIRDVNGEVVNRMRCEYFFPKGESIREGDVIGMLITLPPLSLHKRIVEGTYDPAVDGHASTSGIELSMATNVIRDRIPFHYKSDFCWQQSNVFPTKQLRDYAFNLKETPTFGPPSPMNTEDASLRTLPGSSITIFKNGIKMGTPFKELYAFLPPASRLANGTNNLGLGERENADDGMIGYYPAVSCYGGGAVECRFEGPWWIGPPQAENGEPIRGIGERFNEQIVEDVVADIVDEVEAMLVWGGVDGDVVGNAQMDGTGTGAVGGSEVLKGGVGAAYESAVSAVSAGPGTGPSTVENSVGNVGSPDVGTGHSTFEDAASVGVVGTPNTEEPAARPENITVGHDVEMS
Protein: UDP-glucuronate decarboxylase (EC 4.1.1.35) (F4JAG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKQLHKQMSSKRDEETIPMSQSSPYSPKTLKHPRSLPRSLHYLFREQRLLFILVGILIGSTFFILQPSLSRLGAAESTSLITRSVSYAVTDSPPSRSTFNSGGGGGRTGRVPVGIGRKRLRIVVTGGAGFVGSHLVDKLIGRGDEVIVIDNFFTGRKENLVHLFSNPRFELIRHDVVEPILLEVDQIYHLACPASPVHYKYNPFYKTNVMGTLNMLGLAKRVGARFLLTSTSEVYGDPLEHPQKETYWGNVNPIGERSCYDEGKRTAETLAMDYHRGAGVEVRIARIFNTYGPRMCLDDGRVVSNFVAQTIRKHPMTVYGDGKQTRSFQYVSDLVEGLVALMENDHVGPFNLGNPGEFTMLELAEKSASTFKMSHKETPIPCMKWELCVQVVKEVIDPSATIEFKPNTADDPHKRKPDISKAKEQLNWEPKISLREGLPRMVSDFRNRILNEDEGKGL