wanglab/gogpt-training-data huggingface dataset:
Protein: Alpha/beta-Hydrolases superfamily protein (Expressed protein) (Q9SJM9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Glycosyltransferase)
- Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein
- Polyketide cyclase/dehydrase and lipid transport superfamily protein
- Putative F-box protein At1g32420
- Putative F-box/kelch-repeat protein At1g32430
- Kanadaptin-like protein
- Non-lysosomal glucosylceramidase
- UDP-Glycosyltransferase superfamily protein
- Zinc finger, C3HC4 type
- Disease resistance protein
Sequence:
MATGSTTDSARSPSSGVLQKLLLLFSVCIATSTYKAIQPPPSKLCGSPDGPSITGPRIKLRDGRQLAYKEHGVPRDEATHKIIVVHGSDSCRHDNAFAALLSPDIKEGLGVYMVSFDRPGYAESDPDPNRTPKSLALDIEELADQLSLGSKFYVIGYSMGGQATWACLKYIPHRLAGVTLVAPVVNYWWKNFPSEISTEAFNQQGRNDQWAVRVAHYAPWLTHWWNSQSWFPGSSVVARNLGMLSKADKEIMFKLGAARSQHEAQIRQQGTHETLHRDMIVGFGTWEFDPMELENLFPNNEGSVHLWQGDDDVLVPVTLQRYIAKKLPWIHYHEIPGAGHLFPFAPGMVNNIVKTLLTNDGVKK
Protein: Oxidant-induced cell-cycle arrest protein 5 (Q5A679)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Rab family GTPase
- Oxidant-induced cell-cycle arrest protein 5
- Oxidant-induced cell-cycle arrest protein 5
- GTPase-activating protein GYP5
- Ric1p
- Small ribosomal subunit protein bS6m
- Oxidant-induced cell-cycle arrest protein 5
- Myosin 2
Sequence:
MGKKKQEMSQVYNGSKNEFIFGEQGGKGRNLSSFLRNLSLTGSSSSVDSHRDSYEEVNSNIYGSLSYSKNNRSSGNLNSGSIFQPRPASSGNRTVSLGHIGRHHSPKSQHRRSHSNTRYADLDDDWDAGLDEVVVKPNPPPMLDSLYPDLTVQLPSQVPEKSQHKESMDDIDLEAKAEISKLNQLNSKYAKFRKILASDTIINLQDLRKLAWNGIPNELRALSWLLLLGYLPTNKSRQSSTLKRKRQEYLDGLGSVTIEFHEDPPDNNSNVSLSNVNRDKQLYHQIKIDVKRTNPTIKLYSYPATQVSLRKILYLWAVRHPASGYVQGINDLSTPFYQIFLNNYIWQLQRKKQGEVEDKDLFIPGYMAGTDEEDPEEQKLLNDPQLMQYSLENFNTEWLSARVTSIIEADTYWCLSRLLENITDNYIHQQPGIIRQVNELKNLISKIDVELLNHFEREGIEFIQFSFRWMNCLLMRELPMQLIIRMWDTYLSETPLGFNTFHTYVCAAFLIKFSSELKEKDFQEIILFLQNPPTSSWTEKDVELMLSEAYIWQSLYKNASAHLR
Protein: Protein MioC (P03817)
Organism: Escherichia coli (strain K12)
Function: Probable electron transporter required for biotin synthase activity.
Interaction partners:
- tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
- Chromosomal replication initiator protein DnaA
- Negative modulator of initiation of replication
- Regulatory protein AsnC
- Sulfite reductase hemoprotein beta-component
Sequence:
MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDLPASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAIDKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWVNLLK
Protein: Lysine--tRNA ligase, mitochondrial (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) (P32048)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the attachment of lysine to tRNA(Lys) in the mitochondrion.
Subcellular location: Mitochondrion matrix {ECO:0000269|PubMed:2016746}.
Interaction partners:
- Glutamine--tRNA ligase
- Isoleucine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, mitochondrial
- Arginine--tRNA ligase, mitochondrial
- Isoleucine--tRNA ligase, mitochondrial
- Arginine--tRNA ligase, cytoplasmic
- Putative proline--tRNA ligase YHR020W
- Methionine--tRNA ligase, cytoplasmic
- Probable proline--tRNA ligase, mitochondrial
Sequence:
MNVLLKRRSLTFAPRWLWCKCRSSRSRPYSLAHAVDTSKMEATRRNGQIVKDLGRYYPSMSESALHDLCQEYKEVTIADFNERFLGNPATLHHEDNPNLLLSINGRIKSIRFSGQKIVFIDLYNGSSGLKNDTQLQLIVNYNKIGGSSEDKANFSEYMNFLKKGDYIKALGYPGFSQSRVKMLSLICNKLPIVLSVSQLPLPSRLNDETKIKSNRVVDYQLNGTQTLLVRARIIKLLRKFLDDRNFVEVETPILSSKSNGAMAKPFITSSKDFDHLELRIAPELWLKRLIISGLQKVYEIGKVFRNEGIDSTHNAEFSTLEFYETYMSMDDIVTRTEDLFKFLITNLQKFFQDTRLPVPKTFSELHLALSENNWKFRKVEFLPTLNKELGIDLMNSGLDINKPSELLKALPKDIAKKYFPSADNTGQLSSLQILNKLSDVFLEQRHCQSTLPTVIYHQPAILSPLAKTDPQNKQVTKRFEVFIKGKEYINAYEEENCPQLQLQKFLQQKQINELTGNKTETLSPVIDYQYVETMKYGMPPVGGFGLGIDRLCMLFCDKKRIEEVLPFGCVDDVNRQ
Protein: Cystinosin, lysosomal cystine transporter (D3ZG79)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
- Lysosomal amino acid transporter 1 homolog
- Carbohydrate kinase-like, isoform CRA_b.
Sequence:
MMKNWLLILTLFLLKFIERSESTVGLSAPPTVKLVNGSSTNVSITLGHPLNSTLVITFEITFSSKNLTIVELPDEVIVPRGEKNASFQVTSQNIGQVTVYLHGNHSNQTCPRIQFLVIHSRIVSVINQVIGWIYFMAWSVSFYPQVIQNWRRKSVVGLSFDFLALNLTGFVAYSVFNIGLLWVPYIQEEFLLKYPNGVNPVDINDAFFSLHAVALTLIVILQCCLYERGNQRVSRPSIGFLVLAWLFILVTMIVAAVGVTTWLQFLFCFSYIKLIITLIKYFPQAYMNFYYKSTKGWSIGGVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGVFTIFFDIVFFIQHFYLYRKKPGLQAAPTGFDSHPSQN
Protein: Smoothelin-C (Q9I8J4)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
MKTYFTIEIKDGRVQPHTQSVTPRIVAAPGSQRAELTLGLRSTPIRITAIPSSTGGIRSISTSSNVVKPMEPELVVEQPQAPRLQPELPNGMEKVQVREVEKKSKLNVEELNRIEDEDVLDKMLDQTTDFEERRLIRNAMRELRQRKRDQREKERDQRLQEMKSQATVSRAGHNTETTTTQSTQSADGSARSTVTKTERLIQSNDGSKTSRTTTMESSYVKRSDNGSSSTFVQPNHPTAHSSKKTGSIFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSTSQARKAMIEKLQKEGGSSPNPAAPRAAVQRSSSCGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPDAFDYSQLTPQNRRHNFEVAFSSAEKHADCPQLLDVEDMVRMREPDWKCVYTYIQEFYRCLVQKGLVKTKKS
Protein: arginine kinase (EC 2.7.3.3) (O45518)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSSQIRGSKQHEDVDPVTIKKIEEAYVMLNGPDGAKCSSLLKKNLTKDVIEKLKTKSTKLGANLYDCIRSGVYCLDALVGVYAPDAEAYTLFAPLFDKIIEDYHGLGPDQKQPPVDLGEGKTKEFPPLDPKGKYIKSTRIRCGRSLNGYQFNPCLTEDNYLEMEEKVKKAFSEFSDEELKGTYYPLDGMSKDTQNQLIADHFLFKEGDRHLQYANACNFWPKGRGIFHNNKKTFLIWVNEEDHLRIISMQEGSDVGAVLERLIKGVRGIEKQVQFSRDDRLGWLTFCPTNLGSTVRASVHIALPKLSAREDFKQICDKLDLQLRGIHGEHSESEGGVYDISNRARLGLSEYEAVKKMYDGVKNLIEMEEKET
Protein: Presequence translocase associated motor 16 (D3ZZV1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004637}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004637}.
Interaction partners:
Sequence:
MAKYLAQIIVMGVQVVGRAFARALRQEFAASQAAADARGRAGHQSAAASNLSGLSLQEAQQILNISKLSPEEVQKNYEHLFKVNDKSVGGSFYLQSKVVRAKERLDEELRIQAQEDREKGQTPKT
Protein: TATA-binding protein-associated factor 2N (Q3TLE4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSDSGSYSQSGGEQQSYSSYGNQGSQGYGQTPQGYSGYGQTTDSSYGQNYGGYSGYGQNQSGYSQSYGSYENQKQSSYGQQSYNNQGQQNTESSGGQGGRAPSYGQSDYGQQDSYDQQSGYDQHQGSYDEQSNYQQHDSYNQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRPDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKNGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSGGGYGGDRGGSYGGDRGGYGGDRGGSYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDSGGYGGDRGGYGGKMGGRNDYRNDQRNRPY
Protein: Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10] (P43527)
Organism: Rattus norvegicus (Rat)
Function: Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD), into active mature peptides. Plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex, it initiates a pro-inflammatory response through the cleavage of the two inflammatory cytokines IL1B and IL18, releasing the mature cytokines which are involved in a variety of inflammatory processes. Cleaves a tetrapeptide after an Asp residue at position P1. Also initiates pyroptosis, a programmed lytic cell death pathway, through cleavage of GSDMD. In contrast to cleavage of interleukins IL1B and IL1B, recognition and cleavage of GSDMD is not strictly dependent on the consensus cleavage site but depends on an exosite interface on CASP1 that recognizes and binds the Gasdermin-D, C-terminal (GSDMD-CT) part. Cleaves and activates CASP7 in response to bacterial infection, promoting plasma membrane repair. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracellularly.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P29466}. Cell membrane {ECO:0000250|UniProtKB:P29466}.
Interaction partners:
- NLR family CARD domain-containing protein 4
- Apoptosis-associated speck-like protein containing a CARD
- Gasdermin D
- Absent in melanoma 2
- NACHT, LRR and PYD domains-containing protein 3
- NLR family, pyrin domain-containing 1A.
- Interleukin-1 beta
- Pyrin
- C-X-C chemokine receptor type 5
- Interleukin-18
Sequence:
MADKVLRAKRKQFINSVSVGTINGLLDELLEKRVLNQEEMDTIKLANITVMEKARDLCDHVTKKGPRASQMFITYICNEDCYLAEILELQSGPSAETVFVTEDSKGGHPFSSETKEKLNKEGGAFPGPSGSLKFCPLEIAQKLWKENHSEIYPIMKTPTRTRLALIICNTDFQHLSRRVGADVDLREMKLLLQDLGYTVKVKENLTALEMTKELKEFAACPEHKTSDSTFLVFMSHGLQEGICGITYSNEVADILKVDTIFQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVGNSEEGFLTDAIFEDDGIKKAHIEKDFIAFCSSTPDNVSWRHPVRGSLFIESLIKHMKEYAWSCDLEDIFRKVRFSFEQPDSRLQMPTTERVTLTKRFYLFPGH
Protein: CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27) (P41272)
Organism: Mus musculus (Mouse)
Function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P26842}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- CD70 antigen
- T-lymphocyte activation antigen CD86
- T-lymphocyte activation antigen CD80
- Tumor necrosis factor ligand superfamily member 4
- Tumor necrosis factor ligand superfamily member 9
- Tumor necrosis factor receptor superfamily member 5
- ICOS ligand
- B-lymphocyte antigen CD19
- Tumor necrosis factor receptor superfamily member 9
- Tumor necrosis factor receptor superfamily member 8
Sequence:
MAWPPPYWLCMLGTLVGLSATLAPNSCPDKHYWTGGGLCCRMCEPGTFFVKDCEQDRTAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECSCSKNWQCRDQECTECDPPLNPALTRQPSETPSPQPPPTHLPHGTEKPSWPLHRQLPNSTVYSQRSSHRPLCSSDCIRIFVTFSSMFLIFVLGAILFFHQRRNHGPNEDRQAVPEEPCPYSCPREEEGSAIPIQEDYRKPEPAFYP
Protein: Juvenile hormone acid O-methyltransferase (EC 2.1.1.325) (Juvenile hormone acid methyltransferase) (BmJHAMT) (Q767F1)
Organism: Bombyx mori (Silk moth)
Function: O-methyltransferase that transfers a methyl group from S-adenosyl-L-methionine (SAM) to the carboxyl group of juvenile hormone acids to produce active juvenile hormones in the corpora allata, the last step during juvenile hormone biosynthesis. Also able to methylate farnesoate to methyl farnesoate.
Interaction partners:
- Farnesoate epoxidase
- Aldedh domain-containing protein
- Aldedh domain-containing protein
- Mitochondrial aldehyde dehydrogenase
- Uncharacterized protein.
- Epoxide hydrolase
- Epoxide hydrolase
- Juvenile hormone epoxide hydrolase
- Glutathione peroxidase
Sequence:
MNNADLYRKSNSLQKRDALRCLEEHANKIKWKKIGDRVIDLGCADGSVTDILKVYMPKNYGRLVGCDISEEMVKYANKHHGFGRTSFRVLDIEGDLTADLKQGFDHVFSFYTLHWIRDQERAFRNIFNLLGDEGDCLLLFLGHTPIFDVYRTLSHTEKWHSWLEHVDRFISPYHDNEDPEKEVKKIMERVGFSNIEVQCKTLFYVYDDLDVLKKSVAAINPFNIPKDILEDFLEDYIDVVREMRLLDRCNNNVGESVSIKFNYKVISVYARKLCLSLM
Protein: Microtubule-associated protein mmb1 (Meiotically up-regulated gene 164 protein) (Mitochondrial microtubule binding protein 1) (O74779)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the cell polarity process and in regulation of microtubule growth. Has a role in meiosis.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:15797925, ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:21856157}. Note=Microtubule-associated. Found on all cytoplasmic microtubules throughout the cell cycle, such as the interphase, the astral, and the postanaphase arrays of microtubules. {ECO:0000269|PubMed:21856157}.
Interaction partners:
- Large ribosomal subunit protein uL23m
- Cytochrome c oxidase subunit 4, mitochondrial
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein uL16m
- Large ribosomal subunit protein bL28m
- Small ribosomal subunit protein uS15m
- Large ribosomal subunit protein bL19m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein bL27m
Sequence:
MLQRLEQLQMQTSNILKELHSTSIFTDSTTSQLHNGGENSVMDTEESSAIDKLSASLQQVNISSPSVPTSQSRVTQGQSLGNTQISNPTSKTNNVRAKARNIRNPSQRLRPSTSLARLSNNAPRIPKEASLHENSISSKESPSVTTSKHVATITKPSTSSIARMSSNARIAAIPRAKSSMAVRSPSRLGNGPNVRSPKVGFNAKSDDSPVVKSPGSNDKPSASPRISVRSLGNSSVVRPPTRTSTTRPLSRVNVTNASGSISKNSTSPSKVKVNASTKIVRPVSAAQTVRPGSRIFRENSASNTQRPNVSATSNSTVRVASSLAVRPVSRNAQARTPSRLEQREVNVKNSSAKIVRPGTSLGVRSPSRIQSTLSSRTTTGNVRTKAANIVRPSSSINRRPPSSINQRPPSNLRILAPSRSRATIHERPSSSILHRHAHSLTSSSFSTKTLATTKEIQNSPTLVESSTVVHHDPSYLQNQTSEINDTNHSSHSSPLDLNRMI
Protein: Leucine-rich repeat receptor-like protein kinase (Putative receptor-like protein kinase) (Q9ZVD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MVMKVSGFSDFEALLELKKGFQGDPSRKVLTSWDAKALSSDRCPLNWYGVTCSSGGVTSIDLNGFGLLGSFSFPVIVGLRMLQNLSIANNQFSGTLSNIGSLTSLKYLDVSGNLFHGALPSGIENLRNLEFVNLSGNNNLGGVIPSGFGSLAKLKYLDLQGNSFSGEVMSLFSQLISVEYVDISRNNFSGSLDLGLAKSSFVSSIRHLNVSGNSLVGELFAHDGIPFFDSLEVFDASSNQLSGSVPVFSFVVSLKILRLQDNQLSASLPPGLLQESSTILTDLDLSLNQLEGPIGSITSSTLEKLNLSSNRLSGSLPLKVGHCAIIDLSNNKISGELSRIQNWGDSVEIIRLSSNSLTGTLPGQTSQFLRLTSLKAANNSLQGVLPFILGTYPELKEIDLSHNQLSGVIPSNLFISAKLTELNLSNNNFSGSLPLQDASTVGNLSLTNIGLSHNSLGGVLSEELTRFHNLISLDLSYNNFEGNIPDGLPDSLKMFTVSANNLSGNVPENLRRFPDSAFHPGNALLNVPISLPKDKTDITLRKHGYHMKTSVKAALIIGLVVGTALLALVCVMFHFMLRKQHDEEKSDVTGEKSIVPKTEPSSSNVIAAKNSVQENESSSSTTSTPSIKAKLPVSSSRFSQYSDSENSSPFLKEPNEELHSESRKDEILSSQVSSSTPSLPKIQNSPDNPTSRQTSMRLDGNLYIFDSSLKLTAEELSRAPAEAIGRSCHGTLYRAVLNSDSVLAVKWLREGTAKGKKEFAREIKKLGNINHPNLVSLQAYYWGPKEHEKLIISRYMDAPCLAFYLQEAGQLNLPPLLLENRLKITLDIASCLSYLHNGEAIPHGNLKSTNVLLKPPELTAHLTDYSLHRLITPEATSEQVLNAAALGYCPPEFASSSKPYPSLKSDVYAFGVILLELLTGKVSGDIVCSDPGVVELTEWVLLLVGQNRATECFDPSIVGSQGSRNPFGVLTDVLQVALSCISPAPERPDMKLVSQELSRIVLKRTAI
Protein: CTP synthase (EC 6.3.4.2) (UTP--ammonia ligase) (Q0WRY1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Alkaline-phosphatase-like family protein
- GMP synthase
- Nucleoside diphosphate kinase II, chloroplastic
- Nucleoside diphosphate kinase IV, chloroplastic/mitochondrial
- Nucleoside diphosphate kinase 1
- Nucleoside diphosphate kinase III, chloroplastic/mitochondrial
- Aspartate--tRNA ligase, chloroplastic/mitochondrial
- Delta-1-pyrroline-5-carboxylate synthase B
- Cytochrome P450, family 705, subfamily A, polypeptide 33
- Protein trichome birefringence-like 21
Sequence:
MKYVVVSGGVVSGLGKGVTASSIGLILKSCGFRVTAIKIDPYLNIDAGTMSPIEHGEVYVLDDGGEVDLDLGNYERFMDIKLTSENNITTGKVYKHVLEKERRGDYLGKTVQVVPHITDAIQKWIERAARIPVDGQSGPADVCVIELGGTIGDIESMPFIEALGQFSYRVGTDNFCLIHVSLVPVLNVVGEQKTKPTQHSVRDLRGLGLSPNILACRSTKPLEDNVKAKLSQFCHVPMENVVTLYDCPNIWHIPLLLKEQKAHEAIFRVLNLEGVAKEPALEEWSLMAKMTDKLHVPVRIAVVGKYTELLDSYLSIHKALLHASVARRKKLIIDWISASDLEQGAKKENPDAYKAAWKLLKGADGVLVPGGFGSRGVEGKMLAAKYARENRIPYLGICLGMQLAVIEYARTILGLADANSTELDPNTKNPCVIFMPEGSKTHMGGTMRLGSRRTYFHSKDSKSARLYGNKSFVDERHRHRYEVNPAMVPRFESSGLTFTGKDETGQRMEIIELPNHPFYVGAQFHPEYKSRPGKPSPLFLGLIGAASGELDTVLLQSYQETVVPRSLPNGKLERVYWKGAAKKPVSVVYSLCDRVYS
Protein: Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) (P53852)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Leucine--tRNA ligase, cytoplasmic
- Valine--tRNA ligase, mitochondrial
- Serine--tRNA ligase, cytoplasmic
- Tyrosine--tRNA ligase, cytoplasmic
- Arginine--tRNA ligase, cytoplasmic
- Tryptophan--tRNA ligase, cytoplasmic
- Elongation factor 1-gamma 2
- Serine--tRNA ligase, mitochondrial
- Arginine--tRNA ligase, mitochondrial
- Isoleucine--tRNA ligase, cytoplasmic
Sequence:
MNIFIKALRRYTIMSTPKIVQPKWKVPTPQAKETVLKLYNSLTRSKVEFIPQSGNRGVTWYSCGPTVYDASHMGHARNYVSIDINRRIIQDYFGYDVQFVQNVTDIDDKIILRARQNYLFDNFVKENDTKFNATVVDKVKTALFQYINKNFTIQGSEIKTIEEFETWLSNADTETLKLENPKFPMHVTAVQNAIESITKGDSMDAEVAFEKVKDVTVPLLDKELGSTISNPEIFRQLPAYWEQKFNDDMLSLNVLPPTVTTRVSEYVPEIIDFVQKIIDNGYAYATSDGSVYFDTLKFDKSPNHDYAKCQPWNKGQLDLINDGEGSLSNFADNGKKSNNDFALWKASKAGEPEWESPWGKGRPGWHIECSVMASDILGSNIDIHSGGIDLAFPHHDNELAQSEARFDNQQWINYFLHTGHLHIEGQKMSKSLKNFITIQEALKKFSPRQLRLAFASVQWNNQLDFKESLIHEVKSFENSMNNFFKTIRALKNDAASAGHISKKFSPLEKELLADFVESESKVHSAFCDNLSTPVALKTLSELVTKSNTYITTAGAALKIEPLIAICSYITKILRIIGFPSRPDNLGWAAQAGSNDGSLGSLEDTVMPYVKCLSTFRDDVRSLAIKKAEPKEFLQLTDKIRNEDLLNLNVALDDRNGQSALIKFLTNDEKLEIVKLNEEKHANELAKKQKKLEQQKLREQKENERKQKAQIKPQDMFKDVTLYSAWDEQGLPTKDKDGNDITKSMTKKLKKQWEQQKKLHEEYFGEDK
Protein: Inner membrane protein YbjM (P64439)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Putative transport protein YbjL
- UPF0325 protein YaeH
Sequence:
MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLFFILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFWCALGALCFLFISSLFKPQHRKNQ
Protein: Krueppel-like factor 2a (Kruppel-like factor 2a) (Q1LXI7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Klf2b protein
- Troponin T type 2a
- Notch receptor 1b.
- Transient receptor potential cation channel, subfamily V, member 4.
- Protein HEG
- Krev interaction trapped protein 1
Sequence:
MALSGTILPSISTFSAQKEKCWENRWKDELDRSMHLSCIADLSNMDNLNRITDDEDLDKYLDLEFILANTAGSDNLGLGMAGDYRMQESRNMYNPTTYSVPEINPSPPPPYTTSLMAELLQSDIDTYCQPSLQGRFLVRPAFPTQDISECIKVEPCMDSYGPVRGMVPKVKQEGNGACMRSYEQPRLANSPQGAGSMTPPQSPAELINTDCQSHSQMCHALTFSQSYQGNTGFPHAAPPQMQLPYQSTHHFSMCDDGLAMPNANQRVLLTPPSSPLELDAKPKRGRRTWPRKRTATHTCTFSGCGKTYTKSSHLKAHHRTHTGEKPYHCSWEGCGWKFARSDELTRHFRKHTGHRPFQCHLCERAFSRSDHLALHMKRHM
Protein: PR domain zinc finger protein 1 (EC 2.1.1.-) (A0A096MJU6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR013212}. Cytoplasm {ECO:0000256|PIRNR:PIRNR013212}.
Interaction partners:
Sequence:
MSEAYLRCWIFSWKSVWVRPCQGLHFKTRLLQGSLLYTALDSYSTVQAAPKCNSGSVKFQGLAETSGIMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSSADGGTSVQAEASLPRNLLFKYAANNSKEVIGVVSKEYIPKGTRFGPLIGEVYTNDTVPKNANRKYFWRIYSREEFHHFIDGFNEEKSNWMRYVNPAHSAREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTVMNLTQTESNPKQYSSEKNELYPKSVPKREYSVKEILKLDSNPSKRKDSYRSNISPYTSEKDMDGFRKNGSPDMPFYPRVVYPIRAPLPEDFLKASLAYGMERPTYITHSPLPSSTTPSPPASSSPEQSLKSASPHGSPGNTVSPVVPGPPEHRDSYSYLNVSYGSEGLGSYPGYAPAPHLPPAFIPSYNAHYPKFLLPPYGISSNGLSTMNNINGINNFSLFPRLYPVYSNLLSGGNLPHPMLNPASLPSSLPTDGARRLLPPEHPREVLVPAPHSAFSLTGAAASMKDESSPPSGSPTAGTAATSEHVVQPKATSSVMAAPSTDGAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRDRPHKCAQCHKSYIHLCSLKVHLKGNCPVVPAPGLPLEDLTRINEEIERFDLSDNADRLEDMEDSVDVTSMVEKEILAIVRKEKEETGLKMSLQKTMGSRLPSSGCSLYESSDLSLMKLPHSNSLPLVPVKVKQETVEPMDP
Protein: Complement C4-B (Basic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Cleaved into: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain] (P0C0L5)
Organism: Homo sapiens (Human)
Function: Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.
Subcellular location: Secreted. Synapse {ECO:0000269|PubMed:26814963}. Cell projection, axon {ECO:0000269|PubMed:26814963}. Cell projection, dendrite {ECO:0000269|PubMed:26814963}.
Interaction partners:
- Complement C4-A
- Complement receptor type 1
- Complement C3
- C4b-binding protein alpha chain
- Membrane cofactor protein
- C4b-binding protein beta chain
- Mannan-binding lectin serine protease 2
- Complement C1s subcomponent
- Complement decay-accelerating factor
- Complement C1r subcomponent
Sequence:
MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFSVVPTAATAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRGSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKASSFLGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV
Protein: Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1) (P00447)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular location: Mitochondrion matrix {ECO:0000250|UniProtKB:Q9UQX0}.
Interaction partners:
- Superoxide dismutase
- Peroxisomal catalase A
- Manganese transporter SMF2
- Small ribosomal subunit protein mS42
- Catalase T
- Small ribosomal subunit protein uS17m
- Small ribosomal subunit protein mS43
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL29m
Sequence:
MFAKTAAANLTKKGGLSLLSTTARRTKVTLPDLKWDFGALEPYISGQINELHYTKHHQTYVNGFNTAVDQFQELSDLLAKEPSPANARKMIAIQQNIKFHGGGFTNHCLFWENLAPESQGGGEPPTGALAKAIDEQFGSLDELIKLTNTKLAGVQGSGWAFIVKNLSNGGKLDVVQTYNQDTVTGPLVPLVAIDAWEHAYYLQYQNKKADYFKAIWNVVNWKEASRRFDAGKI
Protein: Actinodin2 (Zgc:175106 protein) (A9JRX1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Fibroblast growth factor-binding protein 2b
- Cartilage matrix protein
- Fibroblast growth factor binding protein 2a precursor
- MIA SH3 domain-containing
- Cartilage acidic protein 1a
Sequence:
MARLIKIFATALVIVFMSDFLSAGPVKRNEEVDGASEVETDSKSHIRKRRNIAFYRSQPDFWGWYKFFMETNNQEGIEDLDRMYRVYLQNKHRVEEGANFNHYLTHLSQIYKTCANSDDPDCIAESTSKPKANIVMPLPVRQATVAVCNPYLDPYCLYAIRPKAAEEPSPAPAKVPAPILSPLLPLPLKAPLAHYYYAPVMEPFLSAEQRAELLRICNPSDTECLQYHLRAAYGYRPALGPLPSYSHLGCDPTKDPYCQPKLVARSPSGLYHLYPSCNPATDPLCVANVVAPAAQTAESAEAPKDKLCNPLFDEGCNPLTAAKLAALNKPVLEYAPRDEPAPLNLACDPRYDPYCLIGGSAALRKPPPVLPEFQTRHNLGVRGKTKEGYDCYMFYDKDCTPVENQDLRSSAASSKPDCHPFDPNCGRFAAQPSTGAEPAKTVKNGIIEPHPDCDPEIDYNCRLRRSESAGDEPAQPEQGHGKPEHVAPEYPVPRFEDFLRAYMGGYKK