wanglab/gogpt-training-data huggingface dataset:
Protein: Resistin (Adipose tissue-specific secretory factor) (ADSF) (C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein) (Cysteine-rich secreted protein A12-alpha-like 2) (Cysteine-rich secreted protein FIZZ3) (Q9HD89)
Organism: Homo sapiens (Human)
Function: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q99P87}.
Interaction partners:
- Toll-like receptor 4
- Adiponectin
- Adenylyl cyclase-associated protein 1
- Leptin
- Nicotinamide phosphoribosyltransferase
- Complement factor D
- Decorin
- Insulin
- Adiponectin receptor protein 2
- Peroxisome proliferator-activated receptor gamma
Sequence:
MKALCLLLLPVLGLLVSSKTLCSMEEAINERIQEVAGSLIFRAISSIGLECQSVTSRGDLATCPRGFAVTGCTCGSACGSWDVRAETTCHCQCAGMDWTGARCCRVQP
Protein: Taste receptor type 2 member 7 (T2R7) (STC7-4) (T2R30) (T2R6) (mT2R42) (P59530)
Organism: Mus musculus (Mouse)
Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Taste receptor type 1 member 2
- Taste receptor type 1 member 3
- Taste receptor type 1 member 1
Sequence:
MTYETDTTLMLVAVGEALVGILGNAFIALVNFMGWMKNRKIASIDLILSSVAMSRICLQCIILLDCIILVQYPDTYNRGKEMRTVDFFWTLTNHLSVWFATCLSIFYLFKIANFFHPLFLWIKWRIDKLILRTLLACVIISLCFSLPVTENLSDDFRRCVKTKERINSTLRCKVNKAGHASVKVNLNLVMLFPFSVSLVSFLLLILSLWRHTRQIQLSVTGYKDPSTTAHVKAMKAVISFLALFVVYCLAFLIATSSYFMPESELAVIWGELIALIYPSSHSFILILGSSKLKQASVRVLCRVKTMLKGKKY
Protein: Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205) (Q59Q46)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03156}.
Interaction partners:
- GMP synthase
- Adenylosuccinate synthetase
- Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
- Inosine triphosphate pyrophosphatase
- AMP deaminase
- Hypoxanthine phosphoribosyltransferase
- Adenylosuccinate lyase
- Amidotransferase
- IMP-specific 5'-nucleotidase 1
- Pho100p
Sequence:
MVFETSKATSYLKDYPKKDGLSVKELIDSTNFGGLTYNDFLILPGLINFPSSAVSLETKLTKKITLKSPFVSSPMDTVTEENMAIHMALLGGIGIIHHNCTSEEQAEMVRKVKKYENGFINDPVVISPEVTVGEVKKMGEVLGFTSFPVTENGKVGGKLVGIITSRDIQFHEDNKSPVSEVMTKDLVVGKKGISLTDGNELLRSSKKGKLPIVDAEGNLVSLISRTDLQKNQDYPNASKSFHSKQLLCGAAIGTIDADRERLDKLVEAGLDVVVLDSSNGSSVFQLNMIKWIKEKYPELQVIAGNVVTREQAALLIEAGADALRIGMGSGSICITQEVMACGRPQGTAVYGVTEFANKFGVPCIADGGIGNIGHITKALALGASCVMMGGLLAGTAETPGDYFYRDGKRLKTYRGMGSIDAMQQTNTNANASTSRYFSEADKVLVAQGVSGSVVDKGSITKFVPYLYNGLQHSLQDIGIKSIDELRENVDNGEIRFEFRTASAQFEGGVHGLHSYEKRLHN
Protein: Small integral membrane protein 12 (Q96EX1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 15 homolog
- Methenyltetrahydrofolate synthase domain-containing protein
- NHP2-like protein 1
- Nucleolar protein 56
Sequence:
MWPVFWTVVRTYAPYVTFPVAFVVGAVGYHLEWFIRGKDPQPVEEEKSISERREDRKLDELLGKDHTQVVSLKDKLEFAPKAVLNRNRPEKN
Protein: ORM1-like protein 3 (Q8N138)
Organism: Homo sapiens (Human)
Function: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12093374, ECO:0000269|PubMed:19819884}; Multi-pass membrane protein {ECO:0000269|PubMed:12093374, ECO:0000269|PubMed:19819884, ECO:0000269|PubMed:33558762}.
Interaction partners:
- Serine palmitoyltransferase 2
- Serine palmitoyltransferase 1
- Serine palmitoyltransferase small subunit A
- Serine palmitoyltransferase 3
- Gasdermin-B
- Zona pellucida-binding protein 2
- Serine palmitoyltransferase small subunit B
- Palmitoyltransferase ZDHHC9
- Golgin subfamily A member 7
- Alpha-1-acid glycoprotein 1
Sequence:
MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSVLIPKLPQLHGVRIFGINKY
Protein: CoA-binding domain-containing protein (A0A0H2UMW1)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADAKIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA
Protein: Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4) (Q96K17)
Organism: Homo sapiens (Human)
Interaction partners:
- Nascent polypeptide associated complex subunit alpha
- Nascent polypeptide-associated complex subunit alpha-2
- NAC-alpha domain-containing protein 1
- Large ribosomal subunit protein eL31
- Nuclear pore complex protein Nup93
- Nuclear pore complex protein Nup205
- Nuclear pore complex protein Nup155
- Large ribosomal subunit protein uL23
- Transcription factor BTF3
- Small ribosomal subunit protein eS19
Sequence:
MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN
Protein: Ribosomal protein uL3 glutamine methyltransferase (L3 MTase) (uL3 MTase) (EC 2.1.1.298) (N5-glutamine methyltransferase PrmB) (P39199)
Organism: Escherichia coli (strain K12)
Function: Specifically methylates the 50S ribosomal protein L3 on 'Gln-150'. Does not methylate the translation termination release factors RF1 and RF2.
Interaction partners:
- Ribosomal protein L11 methyltransferase
- Chorismate synthase
- Penicillin-insensitive murein endopeptidase
- Peptide chain release factor RF1
- HTH-type transcriptional regulator McbR
- Elongation factor P lysine hydroxylase
- Probable membrane transporter protein YfcA
Sequence:
MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPDAEVDAVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSDLPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKEQLIAAREHFAIYKD
Protein: Large ribosomal subunit protein uL5B (60S ribosomal protein L11-B) (P0CT78)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000250|UniProtKB:P0C0W9}.
Interaction partners:
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL16A
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL18A
- Large ribosomal subunit protein eL28
- Small ribosomal subunit protein uS9B
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS2A
- Small ribosomal subunit protein uS3
Sequence:
MAEKAQNPMKELRISKLVLNISLGESGDRLTRAAKVLEQLSGQTPVFSKARYTIRRFGIRRNEKIACHVTVRGPKAEEILERGLKVKEYELKKRNFSATGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMDRPGMRVARRKAQRGRVGYTHKINAEDTINWFKQKYDAVVLGK
Protein: Transmembrane protein 14C (Q0P436)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for normal heme biosynthesis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial glutathione transporter SLC25A39
- ATP-binding cassette sub-family B member 10, mitochondrial
- Iron-sulfur clusters transporter ABCB7, mitochondrial
- Iron-sulfur cluster assembly 1 homolog, mitochondrial
- Solute carrier family 22 member 4.
- Mitoferrin-1
- ATP-binding cassette sub-family B member 6
- Ferrochelatase
- Protoporphyrinogen oxidase
- Caseinolytic mitochondrial matrix peptidase chaperone subunit Xa.
Sequence:
MAVDWAGYGYAALVASGGVIGYVKAGSVPSLAAGLVFGGLAGFGAYQTSQDPGNIWVSLAASGTLAAIMGKRFYNSRKITPAGLIAGASVLMLAKLGAGMLQKPQKS
Protein: NSFL1 cofactor p47 (p97 cofactor p47) (Q9CZ44)
Organism: Mus musculus (Mouse)
Function: Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O35987}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:O35987}. Chromosome {ECO:0000250|UniProtKB:O35987}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:O35987}. Note=Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks. Localizes to centrosome during mitotic prophase and metaphase. {ECO:0000250|UniProtKB:O35987}.
Interaction partners:
- Transitional endoplasmic reticulum ATPase
- UBX domain-containing protein 6
- UBX domain-containing protein 2A
- Ubiquitin recognition factor in ER-associated degradation protein 1
- UBX domain-containing protein 1
- Nuclear protein localization protein 4 homolog
- UBX domain-containing protein 7
- Tether containing UBX domain for GLUT4
- Deubiquitinating protein VCPIP1
- FAS-associated factor 1
Sequence:
MAEERQDALREFVAVTGTEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEEEEEEEGQRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGERRRHSGQDVHVVLKLWKTGFSLDNGDLRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLNTSSPAQQAENEAKASSSILINEAEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFVLMTTFPNKELADENQTLKEANLLNAVIVQRLT
Protein: Myeloperoxidase (D3ZGE2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MKLFLALAGLLAPLAMLQTSTGATPALPGEVANSVVLDCMEEAKRLVNKAYKERRESSIKQSLRSGSASPMELLSYFKQPVAGTRTAVRAADYLHVALDLLKRKLQPLWPRPFNVTGDMRSSEMPELTSMHTLFVREHNRLATELKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKYLPQYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNQYRSTGPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDGDRFWWENPGVFSKQQRQALATISLPRIICDNTGITTVSKNNIFMSNSHPRDFVSCNTLPKLNLASWKET
Protein: Large ribosomal subunit protein eL29 (60S ribosomal protein L29) (YL43) (P05747)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein uS15
- Large ribosomal subunit protein eL38
- Small ribosomal subunit protein eS12
- Large ribosomal subunit protein uL30A
- Large ribosomal subunit protein eL36B
- Large ribosomal subunit protein uL16
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein eL24B
- Large ribosomal subunit protein uL6B
- Large ribosomal subunit protein eL19A
Sequence:
MAKSKNHTAHNQTRKAHRNGIKKPKTYKYPSLKGVDPKFRRNHKHALHGTAKALAAAKK
Protein: Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70) (O94826)
Organism: Homo sapiens (Human)
Function: Acts as receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner. Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection. Upon Sendai virus infection, recruits HSP90AA1:IRF3:BAX in mitochondrion and the complex induces apoptosis.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:20628368, ECO:0000269|PubMed:25609812, ECO:0000269|PubMed:33723040}; Single-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: Note=(Microbial infection) During parasite T.gondii-mediated infection, enriched at the interface between the host mitochondria and the parasitopharous vacuole. {ECO:0000269|PubMed:33723040}.
Interaction partners:
- Heat shock protein HSP 90-beta
- Heat shock protein HSP 90-alpha
- Mitochondrial import receptor subunit TOM7 homolog
- Mitochondrial import receptor subunit TOM22 homolog
- Mitochondrial import receptor subunit TOM40 homolog
- Mitochondrial import receptor subunit TOM20 homolog
- Mitochondrial import receptor subunit TOM5 homolog
- Mitochondrial import receptor subunit TOM6 homolog
- Heat shock 70 kDa protein 4
- Mitochondrial antiviral-signaling protein
Sequence:
MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL
Protein: Plasmodesmata-located protein 6 (PD-located protein 6) (Cysteine-rich repeat secretory protein 12) (Q9ZU94)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Modulates cell-to-cell trafficking.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q8GXV7}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q8GXV7}. Cell junction, plasmodesma {ECO:0000269|PubMed:18215111, ECO:0000269|PubMed:20886105}. Note=Co-localizes with the Grapevine fanleaf virus (GFLV) 2B-MP at the base of tubules within modified plasmodesmata.
Interaction partners:
- FT-interacting protein 4
- WAT1-related protein At2g40900
- Glucan endo-1,3-beta-glucosidase 10
- Probable calcium-binding protein CML49
Sequence:
MFATKTVLFIAVVSLLGTFSSAAVDTFIYGGCSQEKYFPGSPYESNVNSLLTSFVSSASLYTYNNFTTNGISGDSSSVYGLYQCRGDLSSGSGDCARCVARAVSRLGSLCAMASGGALQLEGCFVKYDNTTFLGVEDKTVVVRRCGPPVGYNSDEMTRRDSVVGSLAASSGGSYRVGVSGELQGVAQCTGDLSATECQDCLMEAIGRLRTDCGGAAWGDVYLAKCYARYSARGGHSRANGYGGNRNNNDDDEIEKTLAIIVGLIAGVTLLVVFLSFMAKSCERGKGGK
Protein: Clarin-1 (Usher syndrome type-3 protein homolog) (Q8K445)
Organism: Mus musculus (Mouse)
Function: May have a role in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in analogous synapses within the retina.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P58418}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- pre-mRNA splicing regulator USH1G
- Harmonin
- Whirlin
- Usherin
- Cadherin-23
- PDZ domain-containing protein 7
- Protocadherin-15
- Unconventional myosin-VIIa
- Calcium and integrin-binding family member 2
- Adhesion G-protein coupled receptor V1
Sequence:
MPSQQKKIIFCMAGVLSFLCALGVVTAVGTPLWVKATILCKTGALLVNASGKELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLVQAIPVSIHINIILFSMILVVLTMVGTAFFMYNAFGKPFETLHGPLGLYLVSFISGSCGCLVMILFASEVKVHRLSEKIANFKEGTYAYRTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFTKSKETETTNVASDLMY
Protein: Naphthalene 1,2-dioxygenase system, ferredoxin component (P0A185)
Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
Function: Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene. Functions as an intermediate electron transfer protein via a specific interaction with iron sulfur protein components (ISP) (NdoB and NdoC). Also able to catalyze the cis-dihydroxylation of biphenyl and phenanthrene.
Interaction partners:
Sequence:
MTVKWIEAVALSDILEGDVLGVTVEGKELALYEVEGEIYATDNLCTHGSARMSDGYLEGREIECPLHQGRFDVCTGKALCAPVTQNIKTYPVKIENLRVMIDLS
Protein: Large ribosomal subunit protein eL6 (60S ribosomal protein L6) (Q54D63)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL16
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein eL43
- Large ribosomal subunit protein eL28
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein eL20
Sequence:
MALDNKFVAKGLRLYSARSVANRTKTFVAKKNKVVAPKKVVAPVTPVEKTFGKGKRVIAAKASKFAPSIPAEIRSTAAKKVQQKVALRKSITPGTVLIILAGRFAGKRVVALKQLDSGLILITGPFKVNGVPLRRIDQRYVIATSTKIDVSSVKVAATINDAYFAAEKKSTTKSEGAFFSDEKKAEKKKIADSRVADQKSVDSAILAVLKKEKFLTVYLKTKFYLKKGEFPHQLKF
Protein: D-aminoacyl-tRNA deacylase 1 (EC 3.1.1.96) (Gly-tRNA(Ala) deacylase 1) (Gly-tRNA(Gly) deacylase 1) (F1QGC8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: D-aminoacyl-tRNA deacylase, with no observable activity on tRNAs charged with their cognate L-amino acid (By similarity). Hydrolyzes correctly charged, achiral, glycyl-tRNA(Gly). Deacylates mischarged D.melanogaster and E.coli glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site (By similarity). By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8IIS0}.
Interaction partners:
- Tyrosine--tRNA ligase, cytoplasmic
- Tyrosine--tRNA ligase
Sequence:
MKAIIQRVTRASVTVGEEQISSIGRGLCVLLGISVEDTQKDVDYMVRKILNLRVFEDENGRAWSRSVMDGELEVLCVSQFTLQCLLKGNKPDYHAAMPAELAQPFYNNMLEQLRETYKPELIKDGQFGAKMQVLIQNDGPVTIQLESPPAPTDPKLLSKQEKQQQRKEKTRSKGPSDSSREKAAQRSKVDPSASSGAEGDVSSEREP
Protein: Dof zinc finger protein DOF4.1 (AtDOF4.1) (Q9M161)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Uncharacterized protein At4g00950
- AT4g00920 protein
- NC domain-containing protein-like protein
- Wall-associated receptor kinase-like protein
- ATPase, F1 complex, OSCP/delta subunit protein
- F-box protein At4g00893
- DBH-like monooxygenase
- SWAP
- Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MOK16
- RING/U-box superfamily protein
Sequence:
MDHHQYHHHDQYQHQMMTSTNNNSYNTIVTTQPPPTTTTMDSTTATTMIMDDEKKLMTTMSTRPQEPRNCPRCNSSNTKFCYYNNYSLAQPRYLCKSCRRYWTEGGSLRNVPVGGGSRKNKKLPFPNSSTSSSTKNLPDLNPPFVFTSSASSSNPSKTHQNNNDLSLSFSSPMQDKRAQGHYGHFSEQVVTGGQNCLFQAPMGMIQFRQEYDHEHPKKNLGFSLDRNEEEIGNHDNFVVNEEGSKMMYPYGDHEDRQQHHHVRHDDGNKKREGGSSNELWSGIILGGDSGGPTW
Protein: Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) (P41413)
Organism: Rattus norvegicus (Rat)
Function: Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors.
Subcellular location: [Isoform PC5A]: Secreted {ECO:0000250}. Note=Secreted through the regulated secretory pathway. {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform PC5B]: Endomembrane system {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Type I membrane protein localized to a paranuclear post-Golgi network compartment in communication with early endosomes. {ECO:0000250}.
Interaction partners:
- Lipoprotein lipase
- Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
- Transcription factor Sp6
Sequence:
MDWGWGSRCCRPGRRDLLCVLALLAGCLLPVCRTRVYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDLSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYGAEDYAGPCDPECSEVGCDGPGPDHCTDCLHYHYKLKNNTRICVSSCPPGHFHADKKRCRKCAPNCESCFGSHADQCLSCKYGYFLNEETSSCVAQCPEGSYQDIKKNICGKCSENCKTCTGFHNCTECKGGLSLQGSRCSVTCEDGQFFSGHDCQPCHRFCATCAGAGADGCINCTEGYVMEEGRCVQSCSVSYYLDHSLEGGYKSCKRCDNSCLTCNGPGFKNCSSCPSGYLLDLGMCQMGAICKDGEYIDEQGHCQICDASCAKCWGPTQDDCISCPITRVFDDGRCVMNCPSWKFELKKQCHPCHHTCQGCQGSGPSNCTSCKAGEFQDSEYGECMPCEEGCVGCTVDDPGACTSCATGYYMFERHCYKACPEKTFGEKWECKACGTNCGSCDQHECYWCEEGFFLSSGSCVQDCDPGFYGDQELGECKPCHRACETCTGLGYNQCSSCPEGLQLWHGTCIWPTWPHVEGKVWNEAVPTEKPSLVRSLPQDRRKWKVQIKRDATRQYQPCHSSCKTCNGSLCTSCPAGTYLWLQACVPSCPQGTWLSVRSSSCEKCAEGCASCSGDDLCQRCLSQPSNTLLLHEGRCYHSCPEGFYAKDGVCEHCSSPCKTCKGNATSCHSCEGDFVLDHGVCWETCPEKHVAVEGVCKHCPERCQDCIHEKTCKECMPDFFLYNDMCHHSCPKNFYPDMRQCVPCHKNCLGCNGPKEDDCKACADTSKVLHNGLCLDECPKGTYKDEVNDECRDCPESCLICSSAWTCLTCREGFTVVQDVCTAPKECAAIEYWDVGSHRCQPCHRKCSRCSGPSENQCYTCPRETFLLNTTCVKECPEGYHTDKDSHQCVPCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSGRCEKCDKSCKTCRGPQPTDCQSCDTFFFLLRSKGQCHLACPEHYYADQHAQTCERCHPTCDKCSGKEAWNCLSCVWSYHLLKGICTPECIVGEYRDGKGENFNCKKCHESCMECKGPGSKNCTGCSAGLLLQMDDSRCLRCCNASHPHRSQDCCDCQSSTDECILPASDDTVFHEHTKTALLVTSGAMLLLLLGAAVVVWRKSRSQPVAKGRYEKLAEPTVSYSSYRSSYLDEDQVIEYRDRDYDEDDEDDIVYMGQDGTVYRKFKYGLLDEAEDDELEYDDESYSYQ