wanglab/gogpt-training-data huggingface dataset:
Protein: chitin synthase (EC 2.4.1.16) (B9W9T6)
Organism: Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) (Yeast)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MSNFRDSSSPRRGYSEFDPESGEGLGRKKSLIRPERSRMDENHPRFHYTQVANQESNHIKVQPSSTGVDPRKSNELSTSRSHLSNYATPSHQEEDEDEGIPLMDIHNASPNVSSDQNNDLKGGREVYGLNDEINDYGNSPKKNQVISSSRPLNKEKPTKPKHDIYFWKVYCYAITFWAPAPLLKLFGLPTKDRQFAWREKIGLISCILYIGAFVAYLTFGFTKTVCSSQVVRTQINHVNGGYLIINGRAYDLTSSQHPKAAGIQAGANVLYPPMNAGGKDASFLFQNVNGNCKGLIKPRDNCSIPYNGDELAWYMPCRLFNQDGSTKPNNTFAYYKGWACHTSETARDAYYKLKVNGDVYFTWDDVKNSSRNLVVYSGNVLDLDLINWIETDDVTYPELFDKLRDDETYRGLDISLVLTNSEERQAARCLTEIIKVGSIDTDTIGCIASQVVLYVSLVFILSVVVVKFIMACWFKWVTSRKQGATMYDSKAWAKRNREIEDWVDHDHGIGAEVKTVPVKARANYKAAKTNRQSVFHRAQKLSLGPNADLSQYYDNPNALSKTFKYTTMSTQAALLGRNGYGKRGNNANKSVSGGFNGRQSNLYLTDQGSSTDLLNRPISSYNPFDSMGDDSIVINGLSPDIIHPDVVPQPPVEYQPFGYPLAHTINLVTCYSEDEDGIRITLDSIATTDFPNSHKLILVICDGLIKGSGNDETTPDIVLDMMSDFTVPRDEVEAYSYVAVAQGSKRHNMAKVYAGFYKYNDETVPPEKQQRIPMITIVKCGTPEEASAPKPGNRGKRDSQIILMSFLQKVVFDERMTSLEYEMLQSIWRVTGLMAEFYEIVLMVDADTKVFPDSLTHMVAEMVKDPTIMGLCGETKISNKAQTWVTAIQVFEYYISHHQAKAFESIFGGVTCLPGCFCMYRIKAPKGSDGYWVPILANPDIVERYSDNVVDTLHRKNLLLLGEDRYLSSLMLRTFPKRKQVFVPKAACKTVVPDKFKVLLSQRRRWINSTVHNLFELVLVKDLCGTFCFSMQFVIFIELIGTLVLPAAITFTIYVIIVAIVSKPTPVMSLVLLAVIFGLPGCLIVITVSSLSYLVYFVIYLFALPIWNFVLPSYAYWKFDDFSWGETRTVAGGDKGDHSAVEGKFDSSKIAMKRWREWERERRNTENRKQQQQQQLTNNSSNNLAVPGAAWDPSNTGGNLIDDLSQGSSSGSG
Protein: Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2) (Q9ULK5)
Organism: Homo sapiens (Human)
Function: Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Segment polarity protein dishevelled homolog DVL-1
- Prickle-like protein 1
- Prickle-like protein 2
- Prickle planar cell polarity protein 3
- Protein scribble homolog
- Prickle-like protein 4
- Segment polarity protein dishevelled homolog DVL-2
- Segment polarity protein dishevelled homolog DVL-3
- Cadherin EGF LAG seven-pass G-type receptor 1
- Protein Wnt-5a
Sequence:
MDTESQYSGYSYKSGHSRSSRKHRDRRDRHRSKSRDGGRGDKSVTIQAPGEPLLDNESTRGDERDDNWGETTTVVTGTSEHSISHDDLTRIAKDMEDSVPLDCSRHLGVAAGATLALLSFLTPLAFLLLPPLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVVSYWLFYGVRILDARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLAKKVSGFKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQKNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV
Protein: Rab family GTPase (Q5A2B1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Pep7p
- Rab GDP dissociation inhibitor
Sequence:
MSETSHSSILPPPYKIVLLGDSSVGKTSLVHRFTTNRFDTHTPNTIGAAFITKEFSPHENHERKVRLEIWDTAGQERYRSLTPMYYRNARVALVCFDLSKFESTFNTAKYWIQQLELNNSSDSREKIEIRLVGTKRDLVSTIDDATKDQVNKLITEQSNVVKFHETSSKEGTGIESLFEDIVTNIEETFFTQYYEQNRDTSDQIGNMLRTRQTSNSYCC
Protein: Inhibitor of CDK, cyclin A1 interacting protein 1 (A0A8I6GGY4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MQGQEDGDSILPFAKCSRVVSRSSPCSLPSQKSRPMPQPYGEIFWENLSRRSNSNWMIEQYIPPILRATGCSQPGLHPLEGLPPPEKLWRRKGKKLHLERMQKGLGSTPARVRAVTYHLEDLRRRQGIINELKKAQWGSSEATPELPVFEEGCELLSTTKYLDVEEERATYPQGENYFVTPRDQLLWSPWTPVGQQGTYASGQLNSLAYSTVTARKNPIYSPQRMELESEE
Protein: Ras-GEF domain-containing family member 1B (GPI gamma-4) (Q0VAM2)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
Subcellular location: Early endosome {ECO:0000250}. Late endosome {ECO:0000250}. Midbody {ECO:0000269|PubMed:23894443}. Note=May shuttle between early and late endosomes (By similarity). Localizes to midbody at telophase. {ECO:0000250}.
Interaction partners:
- cGMP-dependent protein kinase 2
Sequence:
MPQTPPFSAMFDSSGYNRNLYQSAEDSCGGLYYHDNNLLSGSLEALIQHLVPNVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCVEHQRLSDPDSDKNQMRKIAPKILQLLTEWTETFPYDFRDERMMRNLKDLAHRIASGEEQTYRKNVQQMMQCLIRKLAALSQYEEVLAKISSTSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTVPVFSEDALYLASYESEGPENHIEKDRWKSLRSSLLGRV
Protein: Meiotically up-regulated gene 14 protein (Q9P5M9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Acireductone dioxygenase-requiring))
- Xylulose kinase
- Pdp3-interacting factor 1
- Fructose-1,6-bisphosphatase
Sequence:
MAKVTGLPEFEDLHTKRKWMLNHMAAAFRMFGRNGYNEGTAGHVTVRDPIDENTFWINPLEVPFSLMKPSDLVHINSDGEIIGGSKMKYNTSGFAIHYEMHKVRPEVICVCHVHSIYGKAFSALGKPLDMLNTDCCVFYNNHGIYFDMDDVISMPEEGRRTAKGLADYKAVLVQNHGIMTVGTTVDEAAYLLSLMERSCQIQLLIDSATKVGERKHVHPTRAKAIRENADNPVGLYTAQQPNFLYEVACSNGELEII
Protein: Glucosaminyl (N-acetyl) transferase 2 (I-branching beta-1,6-acetylglucosaminyltransferase family polypeptide 3) (Q6T5D9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323}.
Interaction partners:
- Hexosyltransferase
- Hexosyltransferase
- Galactoside alpha-
- Type 2 lactosamine alpha-2,3-sialyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase 3
- Alpha-
- L-Fucosyltransferase
- Galactoside alpha-
- Beta-1,4-galactosyltransferase 4
Sequence:
MNLCMKFFAFTALSVVIFVVFYHSQLSLPNLYQRFNSSSERTSVIACDYGLQNHSVFVPGITSPHPLEKLSCSQYQILSHYITSPLSEEEADFPLAYVMVIYKDFDTFERLFRAIYMPQNVYCVHVDSKAAETFKEAVRHLLSCFPNAFLASRMERVVYGGFSRLQADLNCMRDLVASKVPWKYVINTCGQDFPLKTNKEIVQYLKGFKGKNLTPGVLPPEHVITRTKYVYKERKGRDGYFMQNTNTLKTPPPHKLVIYFGTAYVALTRDFVNFILNDKRAIDLLEWSKDTYSPDEHFWVTLNRIPGVPGAMPNASWTGNLRAVKWKDMESQNGACHGHYVHDICIYGNGDLQWLINSQSLFANKFEVNTYPLTVECLELRLRERTLNQSDIALQPSWHF
Protein: Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Sodium- and chloride-dependent GABA transporter 3) (GAT-3) (Solute carrier family 6 member 13) (P31649)
Organism: Mus musculus (Mouse)
Function: Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA). Can also mediate transport of beta-alanine, taurine and hypotaurine and is the major taurine transporter in hepatocytes.
Subcellular location: Cell membrane {ECO:0000269|PubMed:22896705}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:22896705}; Multi-pass membrane protein {ECO:0000255}. Note=In the kidney, detected at the basolateral membranes of parts of proximal tubules.
Interaction partners:
- Sodium- and chloride-dependent GABA transporter 3
- Cytosolic arginine sensor for mTORC1 subunit 2
Sequence:
MENRASGTTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTSENATSPVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMICIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKNQPEPTAPATPMTSLLRLTELESNC
Protein: F-box only protein 43 (Early mitotic inhibitor 2) (Emi1-related protein 1) (F-box protein 26) (Xerp1) (Q8AXF4)
Organism: Xenopus laevis (African clawed frog)
Function: Required to prevent anaphase onset in cytostatic factor-arrested oocytes. Inhibits the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase and prevents cyclin degradation. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Interaction partners:
Sequence:
MANLLENFAAHHSMTAGAKKKADHQDTSVSQDSGYSDSLKGFSPDSHKSGNFLETVTEGYENSENIDPTLILSPIKYELSWGADTRESKQLAPLYETPRVGKKEFSLRRRLLISKATSGGNLDFDVSVCSAESCGREKSLRRIPSHEGSLSNSFADSPRDGSYEPIATSTLKTESESGTSCKKWRLSFAQQRSSTLDDSKSDSIPLPEVENISPVQHSLASSTDDSILYEETIFGAPTTPTCNFIVKEEFQTPISNLAANFRFNLCTPDVGHVSDFDISVTEDSAFHSLSLDKSQDSITDHEGSFQELIQKPRETSKAVNNKSRLRKLDRCRRLSTLRERGSQSEVEEEGNEVPVLSSAYKLKVARASVDEENEFSSDESRVHSLLSSDDLTGKPALRVLHEMLLRSTRKRPQQATVQDLLGSSGCFELPEDSLSRLIGRKMGLETFDILAELKNRNLKHILASILDLVNAASICSMCRVSRDWRDVVLQDKSAHQRRKAYIKKLKTEAEQGRQLSFEDSATRLNILSRSALRSVQIQARSAFRTPTSSLTPGDNKSIHSASKHQEYLKVAKTLFTDEALKPCPRCQYPAKYQALKKRGTCSRKDCGFDFCSLCLCTFHGSKECGTGSAKRIPKKEALPGSAQSKRNLKRL
Protein: Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1 (mHag HA-1)] (Q92619)
Organism: Homo sapiens (Human)
Function: Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24086303}. Cell projection, ruffle membrane {ECO:0000269|PubMed:24086303}.
Interaction partners:
- Phospholipid-transporting ATPase ABCA7
- Unconventional myosin-Ig
Sequence:
MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
Protein: Signal recognition particle 9 kDa protein (SRP9) (Q9SMU7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (By similarity). The complex of SRP9 and SRP14 is required for SRP RNA binding (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Signal recognition particle subunit SRP68
- Signal recognition particle 14 kDa protein
- Signal recognition particle 19 kDa protein
- Signal recognition particle subunit SRP54, chloroplastic
- Signal recognition particle subunit SRP54 2
- Signal recognition particle subunit SRP72
- Signal recognition particle subunit SRP54 3
- Signal recognition particle subunit SRP72
- Signal recognition particle subunit SRP54 1
- Cystatin/monellin superfamily protein
Sequence:
MVYIASWDEFVDRSVQLFRADPESTRYVMKYRHCDGKLVLKVTDNKECLKFKTDQAQEAKKMEKLNNIFFTLMARGPDVDLSEVTGKEQMETQPAKKGRGRKQ
Protein: Neutral protease 2 (EC 3.4.24.39) (Deuterolysin) (Neutral protease II) (NPII) (P46076)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Metalloprotease that shows high activities on basic nuclear substrates such as histone and protamine.
Interaction partners:
- Alkaline protease 1
- Dipeptidyl peptidase 4
- Extracellular metalloproteinase NpI
- Dipeptidyl-peptidase 5
- P/Homo B domain-containing protein
- Peptide hydrolase
Sequence:
MRVTTLSTALFALASTAVSAPTAGSSSPGLEVKLTQIDNTRVKAVVKNTGSEEVSFVHLNFFKDAGPVKKVSIYRGQDEVQFEGIKRRLRSSGITKEAVTSLGAGETLEDEFDIASTSDLASGGPVSIRSHGFVPIVVDGKITGYIPYKSNDLTVNVDGGKAAKVTKALSQLTRRTEVTDCKGDAESSLTTALSNAAKLANQAAEAAESGDESKFEEYFKTTDQQTRTTVAERLRAVAKEAGSTSGGSTTYHCNDPYGYCEPNVLAYTLPSKNEIANCDIYYSELPPLAQKCHAQDQATTTLHEFTHAPGVYQPGTEDLGYGYDAATQLSAQDALNNADSYALYANAIELKC
Protein: Steroid (22S)-hydroxylase (EC 1.14.14.178) ((22S)-22-hydroxycampesterol synthase) (6-deoxycathasterone synthase) (Cytochrome P450 90B2) (OsCYP90B2) (Protein DWARF4 homolog) (OsDWARF4) (Steroid 22-alpha-hydroxylase) (Q5CCK3)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Catalyzes the C22-alpha-hydroxylation step in brassinosteroid biosynthesis, which is the rate-limiting step in this biosynthetic pathway. Catalyzes the conversion of campesterol (CR) to (22S)-22-hydroxycampesterol (22-OHCR, 22-hydroxyCR) and of campestanol (CN) to 6-deoxycathasterone (6-deoxoCT). Required for auxin responses involved in the regulation of epidermal cells length of the lamina joint.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Steroid 5-alpha-reductase DET2
- Cytochrome P450 724B1
- Os10g0397400 protein
- Steroid 5-alpha-reductase DET2
- Cytochrome P450 90A3
- Cytochrome P450 90A4
- Cytochrome P450 90D2
- Os05g0200400 protein
- Nitrate reductase
- Nitrate reductase
Sequence:
MAAMMASITSELLFFLPFILLALLTFYTTTVAKCHGGHWWRGGTTPAKRKRMNLPPGAAGWPLVGETFGYLRAHPATSVGRFMEQHIARYGKIYRSSLFGERTVVSADAGLNRYILQNEGRLFECSYPRSIGGILGKWSMLVLVGDPHREMRAISLNFLSSVRLRAVLLPEVERHTLLVLRAWPPSSTFSAQHQAKKFTFNLMAKNIMSMDPGEEETERLRREYITFMKGVVSAPLNLPGTPYWKALKSRAAILGVIERKMEERVEKLSKEDASVEQDDLLGWALKQSNLSKEQILDLLLSLLFAGHETSSMALALAIFFLEGCPKAVQELREEHLGIARRQRLRGECKLSWEDYKEMVFTQCVINETLRLGNVVRFLHRKVIKDVHYKGYDIPSGWKILPVLAAVHLDSSLYEDPQRFNPWRWKSSGSSGGLAQSSSFMPYGGGTRLCAGSELAKLEMAVFLHHLVLNFRWELAEPDQAFVFPFVDFPKGLPIRVHRIAQDDEQE
Protein: Dynein axonemal assembly factor 4 (Q6P010)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, neuron projection {ECO:0000256|ARBA:ARBA00004487}. Dynein axonemal particle {ECO:0000256|ARBA:ARBA00024190}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPLIVRDHTWTQNLSTVYISVPLKAVKTANVHIICTDDYLKVSFPPFLFEVFLFASINEEKSEARIGNGAAVFTLQKRRDEMWEQLCTNIDKEKQKQIREQAVLKVQEKAVEKSKTKATRIQQEKKYALETMMKLESEERERIQKRKDEVCARATAELDFWRETQRKTAKGNENQIKEQRTSTHDNKPVPQKIKHANTSPADTALVKTDNTITGQMRSKQKTKDLPAPRSAGCIQISFTPRVFPTALRESRVPEEEEWLKKQAEARRAIDTDLAELDDLTEDERNPDWLKDKGDKLFMAGNFLAAVNAYNLAIKLNRKMPALFSNRAACHLKLRNLHKAIEDSSQALELLTPAVSANASARLKAHVRRGTAFCQLQLYVEGLQDYQKALEMDPHNAALRADTEQIRELIQGSTPRSKDEN
Protein: Ankyrin repeat domain 11 variant (Q59GC3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
SAGRVNEDRVRSRTMPKGGCPKAPQQEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKLPFTAGANGEQKDSDTEKQGPERKRIKKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMELKVTLKITRLHQRKRPIVSCQTRRTRRTRVSPWGQERS
Protein: E3 ubiquitin-protein ligase (EC 2.3.2.26) (A0A8I6A6J7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
ENLSGPPFPCSDPYVKLSLYVADENRELALVQTKTIKKVGRPVNPSNHRLLFEVFDENRLTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSEQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRSTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEASEGGGEGPEPWETISEEVNMAGDSLSLALPPPPASPVSRTSPQELSEELSRRLQITPDSNGEQFSALIQREPSSRLRSCSVTDTVAEQAHLPPPSTPTRRARSSTVTGGEESTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLVEPQIRRPRSLSSPTVTLSAPLEGAKDSPIRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKASLNPNDLGPLPVSILQRHEMVQKCVLILPKFMGSLCTCPSAPCPSAPCPSAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD
Protein: FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7) (Q9BQS8)
Organism: Homo sapiens (Human)
Function: May mediate microtubule plus end-directed vesicle transport.
Subcellular location: Cytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes.
Interaction partners:
- Microtubule-associated protein 1 light chain 3 beta
- Ras-related protein Rab-7a
- Microtubule-associated protein 1 light chain 3 alpha
- C-X-C chemokine receptor type 6
- Ras-related protein Rab-7b
- Protrudin
- Ras-related protein Rab-40A-like
- Leucine zipper transcription factor-like protein 1
- GABA type A receptor associated protein like 1
- Gamma-aminobutyric acid receptor-associated protein-like 2
Sequence:
MASTNAESQLQRIIRDLQDAVTELSKEFQEAGEPITDDSTSLHKFSYKLEYLLQFDQKEKATLLGNKKDYWDYFCACLAKVKGANDGIRFVKSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLQPKLSSDIVGQLYELTEVQFDLASRGFDLDAAWPTFARRTLTTGSSAYLWKPPSRSSSMSSLVSSYLQTQEMVSNFDLNSPLNNEALEGFDEMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGRTAAEDNVRLTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEERWLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNNYVLSKHGGKKERCCRACFQKLSEGPGSPDSSGSGTSQGEPSPALSPASPGPQATGGQGANTDYRPPDDAVFDIITDEELCQIQESGSSLPETPTETDSLDPNAAEQDTTSTSLTPEDTEDMPVGQDSEICLLKSGELMIKVPLTVDEIASFGEGSRELFVRSSTYSLIPITVAEAGLTISWVFSSDPKSISFSVVFQEAEDTPLDQCKVLIPTTRCNSHKENIQGQLKVRTPGIYMLIFDNTFSRFVSKKVFYHLTVDRPVIYDGSDFL
Protein: 2'-5'-oligoadenylate synthase-like protein (H0YGP3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XHTSLQAGLLRGSVAAAPPGVEGRGARRCADRGGVSEAGAFPGEAWAGPGCAGAEGSQGPSLPNSQPPPEVYVSLIKACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQAHHPGSGRPHPQRGRRVQMGHRCSEGLPVPETGLLL
Protein: ELAV-like protein (Q9PTK5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSNGYEDHMADELIDSKTNLIVNYLPQNMSQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVNPNDAERAISTLNGLRLQSKTIKVSYARPSSDSIKDANLYISGLPKTMTQKDVEEMFGRYGRIINSRVLVDQASGLSRGVAFIRFDKRAEAEDAIKDLNGQKPPGAAEQMTVKFAASPNQVKNTQVIPQVYHQQSRRFGGPVHHQAQRFRFSPMSVDHMSGMSGVNVPGNSSSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTHYEEAAMAIASLNGYRLGDKILQVSFKTSKSHK
Protein: Protein eva-1 homolog C (Protein FAM176C) (SUE21) (P58658)
Organism: Homo sapiens (Human)
Function: Binds heparin.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLLPGRARQPPTPQPVQHPGLRRQVEPPGQLLRLFYCTVLVCSKEISALTDFSGYLTKLLQNHTTYACDGDYLNLQCPRHSTISVQSAFYGQDYQMCSSQKPASQREDSLTCVAATTFQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDQELKLHCHESKFLNIYSATYGRRTQERDICSSKAERLPPFDCLSYSALQVLSRRCYGKQRCKIIVNNHHFGSPCLPGVKKYLTVTYACVPKNILTAIDPAIANLKPSLKQKDGEYGINFDPSGSKVLRKDGILVSNSLAAFAYIRAHPERAALLFVSSVCIGLALTLCALVIRESCAKDFRDLQLGREQLVPGSDKVEEDSEDEEEEEDPSESDFPGELSGFCRTSYPIYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY
Protein: Transcription factor DYT1 (Basic helix-loop-helix protein 22) (AtbHLH22) (bHLH 22) (Protein DYSFUNCTIONAL TAPETUM 1) (Transcription factor EN 49) (bHLH transcription factor bHLH022) (O81900)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Involved in the control of tapetum development. Required for male fertility and pollen differentiation, especially during callose deposition.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Transcription factor MYB35
- Short-chain dehydrogenase reductase ATA1
- Transcription factor bHLH91
- Transcription factor bHLH89
- Transcription factor MYB80
- Transcription factor bHLH10
- Leucine-rich repeat receptor protein kinase EMS1
- Protein SPOROCYTELESS
- Cytochrome P450 703A2
- ABC transporter G family member 26
Sequence:
MGGGSRFQEPVRMSRRKQVTKEKEEDENFKSPNLEAERRRREKLHCRLMALRSHVPIVTNMTKASIVEDAITYIGELQNNVKNLLETFHEMEEAPPEIDEEQTDPMIKPEVETSDLNEEMKKLGIEENVQLCKIGERKFWLKIITEKRDGIFTKFMEVMRFLGFEIIDISLTTSNGAILISASVQTQELCDVEQTKDFLLEVMRSNP
Protein: Ferric siderophore reductase (Ferric iron reductase protein FhuF) (P39405)
Organism: Escherichia coli (strain K12)
Function: Siderophore-iron reductase which is involved in iron removal from the hydroxamate-type siderophores coprogen, ferrichrome and ferrioxamine B after their transport into the cell. Binds both the iron-loaded and the apo forms of ferrichrome.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9990318}. Cell inner membrane {ECO:0000269|PubMed:9990318}; Peripheral membrane protein {ECO:0000269|PubMed:9990318}. Note=Loosely associated with the cytoplasmic membrane. {ECO:0000269|PubMed:9990318}.
Interaction partners:
- Biopolymer transport protein ExbB
- Protein TonB
- Biopolymer transport protein ExbD
- Ferrichrome outer membrane transporter/phage receptor
- Uncharacterized protein YncE
- Ferric enterobactin-binding periplasmic protein FepB
- Iron
- Iron
- Ferric citrate uptake sigma factor FecI
- Isochorismate synthase EntC
Sequence:
MAYRSAPLYEDVIWRTHLQPQDPTLAQAVRATIAKHREHLLEFIRLDEPAPLNAMTLAQWSSPNVLSSLLAVYSDHIYRNQPMMIRENKPLISLWAQWYIGLMVPPLMLALLTQEKALDVSPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQHRMETLISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKTLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK