wanglab/gogpt-training-data huggingface dataset:
Protein: Nicastrin (Anterior-pharynx-defective protein 2) (Q23316)
Organism: Caenorhabditis elegans
Function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch (glp-1 or lin-12). It may represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Gamma-secretase subunit aph-1
- Gamma-secretase subunit pen-2
- Presenilin hop-1
- Presenilin sel-12
- Presenilin spe-4
- Protein lin-12
- Peptidase A1 domain-containing protein
- Peptidase A1 domain-containing protein
- Peptidase A1 domain-containing protein
- Peptidase A1 domain-containing protein
Sequence:
MKKWLVIVLIIAGIRCDGFSDQVFRTLFIGEGNACYRTFNKTHEFGCQANRENENGLIVRIDKQEDFKNLDSCWNSFYPKYSGKYWALLPVNLIRRDTISQLKSSKCLSGIVLYNSGESIHPGDESTAASHDAECPNAASDYYLQDKNEEYCERKINSRGAITRDGLMKIDWRIQMVFIDNSTDLEIIEKCYSMFNKPKEDGSSGYPYCGMSFRLANMAAGNSEICYRRGKNDAKLFQMNIDSGDAPQLCGAMHSDNIFAFPTPIPTSPTNETIITSKYMMVTARMDSFGMIPEISVGEVSVLTSIISVLAAARSMGTQIEKWQKASNTSNRNVFFAFFNGESLDYIGSGAAAYQMENGKFPQMIRSDRTHIHPIRPNELDYILEVQQIGVAKGRKYYVHVDGERYQQNKTQTDRVIDRIERGLRSHAFDLEKPSGSGDRVPPASWHSFAKADAHVQSVLLAPYGKEYEYQRVNSILDKNEWTEDEREKAIQEIEAVSTAILAAAADYVGVETDEVVAKVDKKLITTIFDCLITSNFWFDCDFMQKLDGGRYHKLFNSYGFNQKSTYISMESHTAFPTVLHWLTIFALGSDKETLNVKSEKSCSHLGQFQAFQMYTYTWQPNPYTGNFSCLKSAIVKKVMVSPAVDSQTPEEEMNTRYSTWMESVYIIESVNLYLMEDASFEYTMILIAVISALLSIFAVGRCSETTFIVDEGEPAAEGGEPL
Protein: Small outer capsid protein (Soc) (P03715)
Organism: Enterobacteria phage T4 (Bacteriophage T4)
Function: Capsid decoration protein which helps to stabilize the capsid against extremes of pH and temperature. Once maturation and expansion of the capsid has occured, trimers of soc attach the interfaces between the hexamer of the major capsid protein. Acts as a 'glue' between neighboring hexameric capsomers. Dispensable for the head morphogenesis and phage infection.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04115, ECO:0000269|PubMed:11162794, ECO:0000269|PubMed:15071181}. Note=870 copies decorate the capsid. {ECO:0000250|UniProtKB:Q7Y5B1}.
Interaction partners:
Sequence:
MASTRGYVNIKTFEQKLDGNKKIEGKEISVAFPLYSDVHKISGAHYQTFPSEKAAYSTVYEENQRTEWIAANEDLWKVTG
Protein: Glycerate kinase (EC 2.7.1.31) (HBeAg-binding protein 4) (Q8IVS8)
Organism: Homo sapiens (Human)
Subcellular location: [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:16753811}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Mitochondrion {ECO:0000269|PubMed:16753811}.
Interaction partners:
- Glyoxylate reductase/hydroxypyruvate reductase
- Triokinase/FMN cyclase)
- Alpha-enolase
- Beta-enolase
- Gamma-enolase
- Enolase 4
- Bisphosphoglycerate mutase
- Phosphoglycerate mutase 1
- 4-trimethylaminobutyraldehyde dehydrogenase
- Phosphoglycerate mutase 2
Sequence:
MAAALQVLPRLARAPLHPLLWRGSVARLASSMALAEQARQLFESAVGAVLPGPMLHRALSLDPGGRQLKVRDRNFQLRQNLYLVGFGKAVLGMAAAAEELLGQHLVQGVISVPKGIRAAMERAGKQEMLLKPHSRVQVFEGAEDNLPDRDALRAALAIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTRLLAARGATIQELNTIRKALSQLKGGGLAQAAYPAQVVSLILSDVVGDPVEVIASGPTVASSHNVQDCLHILNRYGLRAALPRSVKTVLSRADSDPHGPHTCGHVLNVIIGSNVLALAEAQRQAEALGYQAVVLSAAMQGDVKSMAQFYGLLAHVARTRLTPSMAGASVEEDAQLHELAAELQIPDLQLEEALETMAWGRGPVCLLAGGEPTVQLQGSGRGGRNQELALRVGAELRRWPLGPIDVLFLSGGTDGQDGPTEAAGAWVTPELASQAAAEGLDIATFLAHNDSHTFFCCLQGGAHLLHTGMTGTNVMDTHLLFLRPR
Protein: G protein signaling modulator 2 (A0A2R8Y6E3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
XHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDASNSIDHRIPNSQRKISADTIGDEGFFDLLSRFQSNRMDDQRCCLQEKNCHTASTTTSSTPPKMMLKTSSVPVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNSQSVLSHLMTNDNKEADEDFFDILVKCQENGIQGREW
Protein: Spermatogenesis-associated protein 25 (Testis-specific gene 23 protein) (Q9BR10)
Organism: Homo sapiens (Human)
Function: May play a role in spermatogenesis.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Neuralized-like protein 2
Sequence:
MSYFRTPQTHPGPLPSGQGGAASPGLSLGLCSPVEPVVVASGGTGPLSQKAEQVAPAAQAWGPALAMPQARGCPGGTSWETLRKEYSRNCHKFPHVRQLESLGWDNGYSRSRAPDLGGPSRPRPLMLCGLSPRVLPVPSEAVGKEASSQPDICILTLAMMIAGIPTVPVPGVREEDLIWAAQAFMMAHPEPEGAVEGARWEQAHAHTASGKMPLVRSKRGQPPGSCL
Protein: Initiation of translation factor 2 (Osteoblast translation factor 3F) (Q9W6Q4)
Organism: Gallus gallus (Chicken)
Interaction partners:
Sequence:
AKDDIDIDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSIEAQGGKADREPSTGKVNTVGEGEDYVIGNSWDTRHLCPRKVSLCCGLGLLSEVSGYFLLYLFKCYSKCQFEIFYPKRVFGDDHHSKSISINFNCGLSVAHSAVIVTAFLTSSSVREVFLDISECCNSQKHVVFMADLSLNYQVENDNEDSLSKQDKKRKGKSKKANLENDYDSEEMEDKDRKSKKTQKAKQDVLSGSDDDDLEIQPKKNKGKTQKSNKKHELSEDEANVEKSKERVGTLSTGESGDESDEFSQPRKGQKKNQKPKSTAALGSGDEEEESSFKVKTVAQKKAEKKERERKKREEEKAKLRKLKEKEELEGGKEAAKPKEAPKKAEEKASPDVAAAPALGEKEKFLQEQRVCNMVSKTVISHDRFYQEARVLTGFEGDLLLYSKFGVVVIWTLSSSLLAHMWLFFLVCSYSGTGVNKSQMVNSHYHTYVAVCKHNFSAQLLLHICYIKSSGPVFVTSETVLFFFIIKCLYSSLENVPHLELVKCWKHQLYLELLRFLGSLILSLLSVADDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKMKEEEERAKREEEERIRRLEELEAKRKEEERLEQERKERR
Protein: Cytochrome P450 71A16 (EC 1.14.-.-) (Marneral oxidase) (Q9FH66)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses triterpene oxidizing activity. Catalyzes the C23 hydroxylation of marneral to form 23-hydroxymarneral. Catalyzes the C23 hydroxylation of marnerol to form 23-hydroxymarnerol.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Marneral synthase
- Thalianol synthase 1
- 2-oxoglutarate
- Small ribosomal subunit protein eS27w
- Cytochrome P450 708A2
Sequence:
MEMMILISLCLTTFLTILLFFKSLLKRPNSNLPPSPWRLPVIGNLHQLSLHPHRALSSLSARHGPLMLLRFGRVPVLIVSSADVAHDVMKTHDLKFANRPITKSAHKISNGGRDLVFAPYGEYWRNVKSLCTIHLLSNKMVQSSEKRREEEITLLMETLEEASLSSSSVNLSKLITNMVSDIMGKVVLGKKYSGEEGTIDVKTITKSFLDAVGLSPVGEYIPSLAWIGKITGSDGKLEKITKQFGDFIEKVLQEHEDTTADKETPDFVDMLLTIQRDETAQCQLDKSDLKVIIFEMFLGSTTTTSAVIEWAMTRLMRNPECLKKLQDEIRSVSKMNSYVSGKEVENMNYLKAVIKEVLRLHPPLPLLVPRLLSEDVKLKGYDITAGTQVIINAWAIQRDTATWGSDAQEFRPERHFDSTWDFVGRNFKYIPFGAGRRLCPGIGLGSVMASVTLANLVKRFDWRVEDGPSGYDKPDLVEGAGIDVCRKFPLVVFPSSA
Protein: Pcdha6 protein (Protocadherin alpha 6) (Q91Y14)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MDFTTEGRLGTRCMLLSLLLLAAWEAGSGQLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVEVEVRDINDNPPVFSVKEQRMLIYESRLPDSLFPLEGASDADVGLNSMLTYKLSPSEYFGLDVKSNSDGNKQIRLLLKKSLDREDAPEHKLLLTATDGGKPELTGSVQLLVTVLDVNDNAPTFQHPEYEVRILENSDNGTTVIRLNASDKDEGTNSAISYSFNRLVPPKTLEQFSIDADTGEIITQGNLDFEQVDVYKIHVDATDKGHPPMVGHCTVLVKVLDENDNVPQITLTSLSLPVREDAALSTVIALISVSDLDSGSNGQVTCSLSPHVPFKLVSTFKNYYSLVLDSALDRETTADYQVVVTARDGGSPSLWTTASVSVEVADVNDNAPSFAQPDYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLGPWTPGSGGVVSELVSPSVGAGQVVTKVRAVDADSGYNAWLSYELHPLAGGTRSLFRVGLYTGEISTTRALEEADAPRHRLLVLVKDHGEPALIATATVLVSLVENSQTPKASSRAQGATGQEVSLVNVNVYLIIAICAVSSLLVLTLMVYTALRCSVPPTEGVCGAGKPVLVCSSAVGSWSYSQQRRQKVCSGEGPPKTDLMAFSPSLPPCPVVGEHQDLNDDHCSRPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Protein: Partitioning defective 6 beta (Partitioning defective 6 homolog beta) (A6YIE2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, tight junction {ECO:0000256|ARBA:ARBA00004435}. Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNKNHRVPSNRTLNAVEVKSKFGAEFRRFSLDRSKPGRFDEFYGLLQHVHRIPNVDLLVGXADVHGDLLPINNDDNYHKAISMATPLLRXFLQRKEEADYSAFGTDTVTRKKTPAALAAVLLRPDTNKKKPPIIISLPKDFRPVSSIIDVDILPETHRRVRLYKHGQEKPLGFYIRDGSSVRVTPQGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSHNLIITVKPANQRNNIVRSSGGGATSGSSGRSSDSSTSFHGYSVPGSTSMTPSHIIQNFEPDEESEDEEDLVIEADRGAKLIPPAKVRATASSSMPVLPRYEPHLDLRPSNGTMATSTSVGSLNAHERRNLEEDGTVITL
Protein: Vacuolar protein 8 (Q59MN0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole. Vacuole inheritance has a role in the regulation of hyphal cell division.
Subcellular location: Vacuole membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Interaction partners:
- Putative lipase ATG15
- Autophagy-related protein 13
- Synaptobrevin homolog YKT6
- Autophagy-related protein 11
Sequence:
MGACCSCLGNRGGDGSHTQLLLAENEREAISALLQYLENRSDVDFFSNGPLRALSTLVYSENIDLQRSAALAFAEITEKDVREVNRDVLEPILILLQSADSEVQRAACGALGNLAVNTENKILIVEMGGLEPLIRQMMSTNIEVQCNAVGCITNLATQDDNKSKIAKSGALIPLTKLAKSKDIRVQRNATGALLNMTHSGENRQELVNAGAVPVLVSLLSNEDADVQYYCTTALSNIAVDEVNRKKLASTEPKLVGQLVHLMDSPSPRVQCQATLALRNLASDSGYQVEIVRAGGLPHLVQLLTCNHQPLVLAAVACIRNISIHPLNEALIIEAGFLKPLVGLLDYTDSEEIQCHAVSTLRNLAASSEKNRTALLAAGAVDKCKELVLKVPLTVQSEISACFAILALADDLKPKLYESHIIDVLIPLTFSENGEVCGNSAAALANLCSRVSNEHKQYILNNWAQPNEGIYGFLIRFLESGSPTFEHIALWTILQLLESNNTEINALIKENETILAGIKNLSASQQQIQQSQIGQTTTTTTTNITNNNTNTNTNTNTTTSTSNEDQFEDPKVELFNLTQQILQILG
Protein: SCAN domain-containing protein 1 (Q2M4I6)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187}.
Interaction partners:
Sequence:
MAAPQPSQDPQSPAAPPEQQEGAGDCAAPSPDSGSSPAPELPGAPAALNTAPYADAALRPGASRPGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLQAILPEAARARRLRRRADVRITG
Protein: Nuclear receptor NHR-114 (Q86PI8)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTPQSSPSSSRDHVCLVCQDFASGYHYGVPSCVGCKTFFRRTIMKKQKYICQFEGNCPVDKTIRCACRYCRFEKCLSVGMDRNALQQNRDPIGYTKRTRRPKKELKTTSDCSSDEGASTPPSVSPLQLSPPPISPLLFQAAPLKPRRCILQTLAEREKCANDLRLSEYLPIRSLHEALCSKALLNDTAFLEKWGQPSERHQIFDLRFVNHDDYHYWHERDWFLLTEYAKTFDVFEALDYQDKAELVRHAAITVPVLVQVWNSPDYGPDTIVFPDGAYFDRTPEPTRRTQQEKVSNVGSRAQAVP
Protein: Cytochrome b5, putative (Q8I599)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- NADH-cytochrome b5 reductase, putative
- Stearoyl-CoA desaturase
Sequence:
MVVKKLKVIDDKELKKLKTESKSCIVINDLIYDVSSFYEHPGGYDLFKEYEGLDATDAFNSIGHSENAKNLMNSFLIGIKKNSKEYKKKEKTKIIENKIEYINYSDEEIKKEEKEPQESKPKENKPTLIKKEDKTNYPVVAGIIILFGVAYYFLFLK
Protein: 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha) (Q54M22)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Dihydrolipoyl dehydrogenase, mitochondrial
- Branched-chain-amino-acid aminotransferase
- Glutathione reductase
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Pyruvate dehydrogenase complex subunit homolog DDB_G0271564
- NADP-dependent malic enzyme
Sequence:
MISQSYRILSRISRNNELKKTFLTNLNCKSSSPSIIRSFCKKQNLDENFEYTNKLEVQELKHYIPCYTIMDQEGVVSKPDQDPNFSKEEVIKMYTTMLTLNVMDSILYDVQRQGRISFYMTSFGEEAIHIGSAAALEMSDTIFAQYRETGVFMWRGFTINDIINQCCTNEHDLGKGRQMPMHFGSRKINLQTISSPLTTQLPQAVGSSYAQKLAGEKNCTIVYFGEGAASEGDFHAAMNFAAALSTPTIFFCRNNKWAISTPSKEQYKGDGIAGRGPNGYGMKTIRVDGNDIWAVYNVTKLARKIAVEEQVPVLIEAMTYRVGHHSTSDDSSRYRTVEEINAWKEGKNPISRLRNYMNHKGWWSDAQEKETIANARTTVRESLVNAEKQYKPSINEIFTDVYDKPTPNLIEQQKELIEHLKLYPDEYPLNQFADSKLILKD
Protein: Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A protein (Q9LKB2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MTSSLPPLIFFFTVFFVHSLSAVSDLHETRSRFKPPQFSPLFFSSLPQNVTKSPTRYFEVQKPPVPNLPTAQQPCSYQILHHDFGYTYAKPPVLSNYTLPSHCSSREFSKIVLEFKSTSQGRQFDRIFGVWLDGVEILRSCTAEPRPNGIVWSVEKDVTKYHSLLVKNETQILSVYLGNLIDKTYTGVYHVDVIFHFYQSESNLQDVSGYSSSKADMILPISRNLPLNDGLWFEIVNSNDTKYKEFEIPRNVYRAVLEVYVSFHENDEFWYGNLPNDYVTANNLSVAGNGPFREVVVSLDGDIAGAVWPFPVVFTGGINPLLWRPITAIGSFDLPSYDIEITPFLGSLLDGKTHKVGFSVTNALNVWYIDANLHLWLDQEKEIVEGKVLDFSRSSLEISSVSDFKGLNGNFTTKAKRSITSVGLVKSSHGDIITNANQEFSYENKMVLGKDGNLQIIDQLIQADDRIHAKRASREIYAAKSIKSFPFYLDSDTLEQQNNTYLAVANVSMAFNEERSESDKGLMRTFKSKLENKQEGQGVMVVKNNLVVSGYGSTQQVYNYVGSDQCYFRNISSYNYTILYDKVESVCKKKTLKLPPRLEHLPRQHPLLA
Protein: Sonic hedgehog protein (SHH) (EC 3.1.-.-) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein 19 kDa product)] (Q62226)
Organism: Mus musculus (Mouse)
Function: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN. Both activities occur in the reticulum endoplasmic. Once cleaved, ShhC is degraded in the endoplasmic reticulum.
Subcellular location: [Sonic hedgehog protein]: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q15465}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q15465}. Note=Co-localizes with HHAT in the ER and Golgi membrane. {ECO:0000250|UniProtKB:Q15465}.; SUBCELLULAR LOCATION: [Sonic hedgehog protein N-product]: Cell membrane {ECO:0000269|PubMed:7891723}; Lipid-anchor {ECO:0000269|PubMed:7891723}. Note=The dual-lipidated sonic hedgehog protein N-product (ShhNp) is firmly tethered to the cell membrane where it forms multimers (PubMed:24522195). Further solubilization and release from the cell surface seem to be achieved through different mechanisms, including the interaction with DISP1 and SCUBE2, movement by lipoprotein particles, transport by cellular extensions called cytonemes or by the proteolytic removal of both terminal lipidated peptides. {ECO:0000269|PubMed:24522195, ECO:0000305|PubMed:22677548}.
Interaction partners:
- Hedgehog-interacting protein
- Protein smoothened
- Protein patched homolog 2
- Cell adhesion molecule-related/down-regulated by oncogenes
- Protein patched homolog 1
- Brother of CDO
- Growth arrest-specific protein 1
- Axin-1
- Low-density lipoprotein receptor-related protein 2
- Protein dispatched homolog 1
Sequence:
MLLLLARCFLVILASSLLVCPGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLRPGDRVLAADDQGRLLYSDFLTFLDRDEGAKKVFYVIETLEPRERLLLTAAHLLFVAPHNDSGPTPGPSALFASRVRPGQRVYVVAERGGDRRLLPAAVHSVTLREEEAGAYAPLTAHGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDGGGGGSIPAAQSATEARGAEPTAGIHWYSQLLYHIGTWLLDSETMHPLGMAVKSS
Protein: Phosphoglycerate kinase 1, chloroplastic (EC 2.7.2.3) (Q9LD57)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May trigger the phosphorylation of FTSZ2-1 and FTSZ2-2.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Triosephosphate isomerase, chloroplastic
- Triosephosphate isomerase, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPB, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPCP2, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPCP1, chloroplastic
- Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1
- Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic
Sequence:
MASAAASSAFSLLKSTGAVASSAGTRARASLLPIPSTSVSARPLGFSATLDSRRFSLHVASKVESVRGKGSRGVVSMAKKSVGDLTSADLKGKKVFVRADLNVPLDDNQTITDDTRIRAAIPTIKYLIENGAKVILSTHLGRPKGVTPKFSLAPLVPRLSELLGIEVTKADDCIGPEVESLVASLPEGGVLLLENVRFYKEEEKNDPEFAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSNPKRPFAAIVGGSKVSSKIGVIESLLEKCDILLLGGGMIFTFYKAQGLSVGSSLVEEDKLELATELLAKAKAKGVSLLLPTDVVVADKFAPDANSKIVPASGIEDGWMGLDIGPDSIKTFNEALDTTQTVIWNGPMGVFEMEKFAAGTEAIANKLAELSEKGVTTIIGGGDSVAAVEKVGVAGVMSHISTGGGASLELLEGKVLPGVIALDEAIPVTV
Protein: Fibroblast growth factor (FGF) (Q8VI80)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Klotho beta
- Fibroblast growth factor receptor
- Fibroblast growth factor receptor
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor 1
- Klotho
- Pro-epidermal growth factor
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- Insulin-like growth factor 1 receptor
Sequence:
MDWMKSRVGAPGLWVCLLLPVFLLGVCEAYPISDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGTAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGTLYGSPHFDPEACSFRELLLKDGYNVYQSEAHGLPLRLPQKDSQDPATRGPVRFLPMPGLPHEPQEQPGVLPPEPPDVGSSDPLSMVEPLQGRSPSYAS
Protein: Transporter (A0A8I6GLX0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
TRRGRSSSENFHVGENDENQERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYLFASFQSVLPWANCSSSWADDNCSRQPIVTGCRVSTDTGGDMFMNISWVNSNNFTCLNGSEVFRPGQLPSEQYWDKVTLRRSSGMDETGVIVWYLALCLLLAWIIVGAALFKGIKSSGKVVYFTALFPYVVLLILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKAMKRMRVPITLGCCLILFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWLFWLWWRACWFVITPILLSAILVWSLVKFHRPNYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVRAEGNILQRIIKCCRPASNWGPYLEKHRGERYKDMAEPAKETDHEIPTISGTRKPE
Protein: GH28335p (Syncrip, isoform C) (Q95TW4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAEGNGELLDDINQKADDRGDGERTEDYPKLLEYGLDKKVAGKLDEIYKTGKLAHAELDERALDALKEFPVDGALNVLGQFLESNLEHVSNKSAYLCGVMKTYRQKSRASQQGVAAPATVKGPDEDKIKKILERTGYTLDVTTGQRKYGGPPPHWEGNVPGNGCEVFCGKIPKDMYEDELIPLFENCGIIWDLRLMMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDELIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWADPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQYGKVERVKKIKDYAFIHFEDRDSAVEAMRGLNGKEIGASNIEVSLAKPPSDKKKKEEILRARERRMMQMMQARPGIVGNLSPTHPSIMSLTPMRPGARMPLRTPIPREYVVGKRKFDGGHQNPADVKRRYPSGLIGNGGSWGSLPLPQQPLGTNGEQWYMDTFSAWS
Protein: Mbd3b protein (Methyl-CpG binding protein 3b) (Methyl-CpG-binding domain protein 3b) (Q7ZZR0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEKNDPTGKKFRSKPQLARYLGNSMDLSSFDFRTGKMLMSKLNKNRQRPRYDNNSQSKGKPDLNTSLPVRQTASIFKQPVTKVTNHPSNKVKTDPQKAIDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDKTLLSAIASALHTSAAPITGQLSAAVEKNPGVWLNTAQPLCKAFIVTDEDIRKQEELVYSVRKRLEEALMADMLAHVEETASEGEALKQEGNCTDEKQEV
Protein: PWWP domain-containing protein 2A (A0A1L8GR68)
Organism: Xenopus laevis (African clawed frog)
Function: H2A.Z-specific chromatin binding protein which plays an important role in the neural crest cell differentiation and/or migration during early development and is essential for the development of the head and eye. Acts as an adapter between distinct nucleosome components (H3K36me3 or H2A.Z) and chromatin-modifying complexes, contributing to the regulation of the levels of histone acetylation at actively transcribed genes (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96N64}.
Interaction partners:
- Nibrin
- Double-strand break repair protein
- Uncharacterized protein
- DNA repair protein RAD50.L
- DNA repair protein RAD50.S
- TP53-binding protein 1
- Uncharacterized protein.
- Ku domain-containing protein.
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- Uncharacterized protein.
Sequence:
MAAVAAAPGPGEAGESEQDSKTTPGEWRLGELQCEPIVAVLDSERQSLIRCEMDSDTLEKAGPVVEQLGGSGTDQVYGIDKNSDFESVSVMDYKPPYRGINQERIAGENKKARHEQLPRHTFLQKEPTPMILSEVRDSGVHTEMCLEEATLSSNNDGSETSLNDPDCDIGSMGTSEGSVVTSGIGSLIPGSEVQVTLDHIIQDALVVSFCHGNRIFSGVLMDLSKRFGPHGIPVTVHPRREYKNKPVESIQEESKSFHEETLLKSEENVTPPEDVTPIQQSESCEIQNLWTTKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKKKIYREEPTSIINAIKLRPRQVLCDKCKNNVVADKKEIRKVATDSYKTEEGKRRRHETITTVNKKLKTDHKVNGKGQHESQKRAGVTKVPNLAHGRGKVVKVPSQTSAAKTQLHTKKVLQNKNMDHVKAREVLKMAKEKAQKKQKVTTSSKNAHSKVHFTRRLQNSNSGTLPPRLRIKPQRYRNEENDSSLKPGLETLRSSKMGIKPQTRYSATRSAGEAPSEIQSPSNGPEEVSSEIQDTNVCVPPEEQDLQQTLGKRGSKSNITVYMAINQKKANSSSASVCSSDSTDDMKSSHSECSSTENFDFPPGSMHTPSSSSASSKEEKKLSNSLKIKMFSKNVSKCVTPDGRTICVGDIVWAKIYGFPWWPARILAITISRKDNGLLIRQEARISWFGSPTTSFLALSQLAPFLENFQSRFNKKRKGLYRKAITEAAKAAKQLTPEVRALLTQFET
Protein: mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (D3ZZH6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- TNF receptor-associated factor
- Thioredoxin
- Death domain-associated protein 6
- Dual specificity mitogen-activated protein kinase kinase 4
- Disabled homolog 2-interacting protein
- mitogen-activated protein kinase kinase
- Serine/threonine-protein kinase/endoribonuclease IRE1
- Parkinson disease protein 7 homolog
- mitogen-activated protein kinase kinase
- RAC-alpha serine/threonine-protein kinase
Sequence:
MGTEAGEGITFSVPPILSAGFCPIPEGGSCRRGGGAATAAEGEPSLQPLLMPPPPPPPGSFWNVESAAAPGTSCPTTAPGSSATRGRGNSGSGGGRRTTVAYVINEASQGQLVVAESEALQSLREACEAVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTVCTGNYTFIPYMVTPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFVQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEEQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHLRVIQASEKLFRLKTPAWYLKSIVETILIYKHFVKLTTEQPTAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFNASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKRFFEMVNTITEEKGRGAEEGDCEGDSLEYDYEHDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSTGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKADPFSFKTRAKSCGEKDGKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGPEEPKLKWEHITTLISSLREFVRSTDRKIIATTLSRLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADPEDLDVDDEHEESPSNQTARRPQPVAEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKMETNRLLEELVRKEKELQALLHQAIEEKDQEIKHLRLKSQPIDTPGFPVCHLNAPGTAIEDSELTGWLRENGADEDTISRFLAEDYTLVDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKGA
Protein: Mini zinc finger protein 2 (AtMIF2) (Q9LJW5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Inhibits zinc finger homeodomain (ZHD) transcription factors by interacting with them to prevent both their nuclear localization and their DNA-binding properties. Involved in integrating signals from multiple hormones by regulating the expression of specific genes.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Histone deacetylase 19
- Zinc finger protein KNUCKLES
- Protein FANTASTIC FOUR 1
Sequence:
MRKRQVVLRRASPEEPSRSSSTASSLTVRTVRYGECQKNHAAAVGGYAVDGCREFMASRGEEGTVAALTCAACGCHRSFHRREIETEVVCDCNSPPSTGN
Protein: MIP04175p (Narrow, isoform A) (Narrow, isoform D) (A1ZAU2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAKIVLFCLLSLLACAAGQRITTIHLDGVQYFISRMNPYSPELNYFLAYQYCRSLGLQLASFETKEKAESMTTYLKNAGYGNYDFWTSGNRLGTGMFLWMSTGLPFNATFDFFENSADAIQAGLLDPVDHNSNTSPQRTARDSSSGAEKGCVILKQPTLKWMPEDCSAVKDFICEQTRCYYYNYGSIPVSSAQG