wanglab/gogpt-training-data huggingface dataset:
Protein: DNA mismatch repair protein msh6 (O74502)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in post-replicative DNA-mismatch repair. Has a role towards base-base mispairs and insertion-deletion loops.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- DNA mismatch repair protein msh2
- Putative MutL protein homolog 1
- DNA mismatch repair protein pms1
- Proliferating cell nuclear antigen
- DNA mismatch repair protein msh3
- Exodeoxyribonuclease 1
- Flap endonuclease 1
- MutS protein homolog 1
- DNA polymerase epsilon catalytic subunit A
- DNA polymerase delta catalytic subunit
Sequence:
MSVGNVGKQREKTKDSSAKTKQKTLFGFFSKIPNVKQEKSDSTLSSSSNHDSNHDTPADVDNSSNVNKNSSSPERELPTSPSHHANTEIDSSSSMLPPPSSDPFSSPLSSSLHRSSPKRPHDSLGEESPGKLLRTSVKQEPDSEEEIDSPTKKKSFKSLDTSIFQAEDQFRHPVSSKLENSELSEVDKPFIASRRSRKPVSYAESDEDEDFDDAPTKGSRHKRIVSDDESDDYVEPDHISEASSEASLPIDEVESMDEDVDGYSDHSVSVAAPIPKKESRKESSNSLYESYRLGSQIASPSPSVSGSASPTKSNKNGVLNREEKRRQRMEAFKKENNERYEWLLDVRDADQNRVGDPNYDPRTLYIPPSAWATFKPFEKQFWKIKKDLMDTVVFFQKGKFYELYENDAAIGHQVFSLKLTDRVNMKMVGIPEASFDYWASQFIAKGYRIARVDQLETALGKEIKDRQRTQKEEKVVQRGLTQVLTSGTLVDEAMLTSDLSTYCMAIKESLQSDNEEPSFGICFIDTSTGGFHMCEFTDDIHRTKLDTLLTQVRPKELILEKSKISQKSIRAIKYCVSSSSIWNFIKPYTEFWDNERVEREIIAGDYFKNGLEGAPKILKSYLSEKPLAISAFGALFWYLRQLKLDKDMCSMGNFDEYDASQQSTSLLMNGQTLKNLEIFSNSFDGGSEGTLFHLLCRCVTPFGKRLFHTWLCHPLRSGTAINARLDVVELIADNPVIRDTIWGFLHKLPDLERLISRVHAGRSKPADFVRVLEGFQRINSAFDQLREEFMEVAEGTLLGEIIQSAPNMKEELEAWTRAFNWQKASEEGVFEPEIGFEAEYDTSQKYQSELKNELYALLEQYKKQLRCSSLNFKNIGKEVYQVEVPSDVKVPVNWCKMSGTKKTNRYYNDELRKKIKKLLEAEELHLAIMSRMQEKFYIRFDSNYEQWLALIKYTASIDCFFSLSQAAAALGEPYCRPEIIEQKDGHLYFEELRHPCINASAASTFVPNDVVLGGESPNMIVLTGPNMAGKSTLLRQVCIAVIMAQLGCWVPAKRASITPMTSIYTRLGANDDIMSARSTFMVELSETKKILDECGPKSLVILDELGRGTSTYDGHAIAYAVLHHLVSNIGCLGFFSTHYQSLCVDFMHHRQVRLMQMAAAVDEKIRRVTFLYKLEDGICPKSYGMNVASMAGLPEKVIDAAEEKASELEQASASFINASDDIALMSDFLQVLRISKSIEPLTAVNIPLILDSFE
Protein: Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2) (O43559)
Organism: Homo sapiens (Human)
Function: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Subcellular location: Membrane; Lipid-anchor.
Interaction partners:
- Tyrosine-protein phosphatase non-receptor type 11
- Growth factor receptor-bound protein 2
- ALK tyrosine kinase receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 4
- Nucleophosmin
Sequence:
MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL
Protein: Transcription antitermination protein NusB (Antitermination factor NusB) (P9WIV1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
Interaction partners:
- Antitermination protein NusB
- Transcription termination/antitermination protein NusG
- Elongation factor P
- Probable cytoplasmic peptidase PepQ
- Transcription termination/antitermination protein NusA
- Small ribosomal subunit protein uS10
- 6,7-dimethyl-8-ribityllumazine synthase
- DNA-directed RNA polymerase subunit omega
- dTDP-4-amino-4,6-dideoxyglucose formyltransferase
- Methionyl-tRNA formyltransferase
Sequence:
MSDRKPVRGRHQARKRAVALLFEAEVRGISAAEVVDTRAALAEAKPDIARLHPYTAAVARGVSEHAAHIDDLITAHLRGWTLDRLPAVDRAILRVSVWELLHAADVPEPVVVDEAVQLAKELSTDDSPGFVNGVLGQVMLVTPQLRAAAQAVRGGA
Protein: Exosporium protein C (J7SGD5)
Organism: Clostridium sporogenes (strain ATCC 15579)
Subcellular location: Spore wall {ECO:0000269|PubMed:27375261}. Note=Localizes to the exosporium. {ECO:0000269|PubMed:27375261}.
Interaction partners:
Sequence:
MMSMDEMRGNYDSNSYKSADHDCHKDCGRVIESQTLPLCEGTNITPTAVTTPVVAKIPVVLAEKEVQIDVEARMKLKEKFFEIKRIKKDVFLTQCELLPRAGVIENGVPITGKLFLSGFVRKNIEFATADCVKHDVVSGEIKHTTEKIPFTCVTEVTYITPPILGNRGIQQKTDLFCGRCDCECECEEERLGKLTCEEFLEDSITLVEKPFCELLGARIFEADIQRKPCYEHGEKVFDELLEKMVVHIRVKVLQLQQVAVNDTDAGTGSMCRK
Protein: Zinc-regulated transporter 1 (High-affinity zinc transport protein ZRT1) (P32804)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High-affinity zinc transport protein.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Zinc-responsive transcriptional regulator ZAP1
- Zinc-regulated transporter 2
- Zinc-regulated transporter 3
- Protein ZPS1
- Vacuolar zinc transporter ZRC1
- Low-affinity Fe
- Vacuolar zinc transporter COT1
- Probable zinc transporter MSC2
- Protein ZRG17
- Zinc transporter YKE4
Sequence:
MSNVTTPWWKQWDPSEVTLADKTPDDVWKTCVLQGVYFGGNEYNGNLGARISSVFVILFVSTFFTMFPLISTKVKRLRIPLYVYLFAKYFGSGVIVATAFIHLMDPAYGAIGGTTCVGQTGNWGLYSWCPAIMLTSLTFTFLTDLFSSVWVERKYGLSHDHTHDEIKDTVVRNTAAVSSENDNENGTANGSHDTKNGVEYYEDSDATSMDVVQSFQAQFYAFLILEFGVIFHSVMIGLNLGSVGDEFSSLYPVLVFHQSFEGLGIGARLSAIEFPRSKRWWPWALCVAYGLTTPICVAIGLGVRTRYVSGSYTALVISGVLDAISAGILLYTGLVELLARDFIFNPQRTKDLRELSFNVICTLFGAGIMALIGKWA
Protein: Syntaxin-1A (dSynt1) (Q24547)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Required for coordinated peristaltic contractions. Recruited by Unc-13-4B to secretory lysosome-related organelles (SLs) that are essential for tracheal lumen fusion between previously separate tracheal branches (anastomosis). Possibly promotes the intracellular fusion of the extending tracheal stalk cell lumens in tracheal fusion cells (Fcs) by interacting with complementary SNAREs (such as Syb) present in the apical membrane of the FC-FC interface and the membranes of the separate tracheal stalk cells.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:7834751}; Single-pass type IV membrane protein {ECO:0000305}. Lysosome membrane {ECO:0000269|PubMed:27323327}; Single-pass type IV membrane protein {ECO:0000305}.
Interaction partners:
- Synaptobrevin
- Synaptosomal-associated protein
- Synaptosomal-associated protein 25
- Neuronal synaptobrevin, isoform J
- Alpha-soluble NSF attachment protein
- Protein ROP
- LD03592p
- Vesicle-associated membrane protein 7
- Synaptotagmin 1
- LD34211p
Sequence:
MTKDRLAALHAAQSDDEEETEVAVNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLEEGNSSVFTQGIIMETQQAKQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKIMILICLTVLGILAASYVSSYFM
Protein: Combgap, isoform J (A8DYD2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MCAAQNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGLTAGGKNNVVRRMFVVNDPSFPPGTQRVITAGGASTVVKKQDNNQQVLSLDKNYLLVDPATAAAAAAAAGGDSGLAHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGSHHHASGGTPSDILPGISVQVQKVIQGLEDNEDSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEAATQQQLATAGEQQQVQVQIMPDGQIHGKVIKYEICRNVMPEDQQQEQADMNAE
Protein: Chromatin modification-related protein eaf3 (Altered polarity protein 13) (ESA1-associated factor 3) (O13953)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). Also involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00972, ECO:0000269|PubMed:12773392}.
Interaction partners:
- Probable chromatin modification-related protein eaf7
- RbAp48-related WD40 repeat-containing protein prw1
- Histone deacetylase clr6
- Protein AF-9 homolog
- Uncharacterized protein C16C9.05
- Uncharacterized protein C2F7.07c
- SWR1-complex protein 4
- Paired amphipathic helix protein pst2
- Enhancer of polycomb-like protein 1
- Chromatin modification-related protein png1
Sequence:
MAVSYKVNERVLCFHGPLLYEAKIVDTEMKGDVTTYLIHYKGWKNSWDEWVEQDRILQWTEENLKTQKELKNAAISTRQKPTSKKSASSTSKHDSTGVKTSGKRSRESSTVTVDGDSHELPSRIKTQKSESPIPQQVKRDGTTDAKNEETTKPENNEKDDFEEEPPLPKHKISVPDVLKLWLVDDWENITKNQQLIAIPRNPTVRAAIAAFRESKISHLNNEIDVDVFEQAMAGLVIYFNKCLGNMLLYRFERQQYLEIRQQYPDTEMCDLYGVEHLIRLFVSLPELIDRTNMDSQSIECLLNYIEEFLKYLVLHKDEYFIKEYQNAPPNYRSLVGV
Protein: eIF-4F 25 kDa subunit (Q9VSB6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Polyadenylate-binding protein
- Eukaryotic translation initiation factor 4E-binding protein
- Eukaryotic initiation factor 4A
- Eukaryotic translation initiation factor 4G1, isoform B
- Eukaryotic initiation factor 4B
- ATP-dependent RNA helicase
- Cytoplasmic FMR1-interacting protein
- ATP-dependent RNA helicase me31b
- Eukaryotic translation initiation factor 5
- Eukaryotic translation initiation factor 4G2, isoform A
Sequence:
MASAQVQSFDIMKQQDQQHQLNSIHKHHHHHEGVPLESNSPEPIDEEIYQVEYKHPLEHVWTLWYLENDRTKHWKDMLNEITEIDSVETFWSLYHTIKTPAELKIGCDYSVFKKGIKPMWEDEANIKGGRWLVTVSKSAKAELDQIWLDILLLMVGQNFEYSDEICGAVINIRNKSNKISVWTANGSNEMAILEIGQKLKILLHLQSHSLQYQLHSDAMSKFNSGVKSVYTL
Protein: Tsukushi (Leucine-rich repeat-containing protein 54) (Q8CBR6)
Organism: Mus musculus (Mouse)
Function: Contributes to various developmental events and other processes such as wound healing and cholesterol homeostasis through its interactions with multiple signaling pathways. Wnt signaling inhibitor which competes with WNT2B for binding to Wnt receptor FZD4 and represses WNT2B-dependent development of the peripheral eye. Plays a role in regulating the hair cycle by controlling TGFB1 signaling. Required for the development of the anterior commissure in the brain by inhibiting neurite outgrowth. Essential for terminal differentiation of hippocampal neural stem cells. Plays a role in regulating bone elongation and bone mass by modulating growth plate chondrocyte function and overall body size. Required for development of the inner ear through its involvement in stereocilia formation in inner hair cells. Facilitates wound healing by inhibiting secretion of TGFB1 from macrophages which prevents myofibroblast differentiation, maintaining inflammatory cell quiescence. Plays a role in cholesterol homeostasis by reducing circulating high-density lipoprotein cholesterol, lowering cholesterol efflux capacity and decreasing cholesterol-to-bile acid conversion in the liver. In one study, shown to negatively regulate sympathetic innervation in brown fat, leading to reduced energy expenditure. In another study, shown not to affect brown fat thermogenic capacity, body weight gain or glucose homeostasis.
Subcellular location: Secreted {ECO:0000269|PubMed:30595550, ECO:0000269|PubMed:31391339, ECO:0000269|PubMed:31535079, ECO:0000269|PubMed:31767170}.
Interaction partners:
Sequence:
MLCSLFLLLLAVGRVQTTRPCFPGCQCEEETFGLFDSFSLIRVDCSSLGPHIVPVPIPLDTAHLDLSSNRLETVNESVLAGPGYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAFTTHSQGRALHVDLSHNLIHRLLPHPARASLPAPTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATINPDAFMGLAGLTHLSLASLQGILHLPPHGFRELPGLQVLDLSGNPKLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLLHHLPALQSVSVGQDVQCRRLVREGAYHRQPGSSPKVVLHCGDTQESAARGPDIL
Protein: Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT) (EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial) (A8MUP2)
Organism: Homo sapiens (Human)
Function: Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria. Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methyl group per binding event.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25023281, ECO:0000269|PubMed:28887308}.
Interaction partners:
- EEF1A lysine methyltransferase 2
Sequence:
MAALRRMLHLPSLMMGTCRPFAGSLADSCLADRCLWDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAVARGGLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGSYGWTVTVQELGPFRGITYFAYLIQGSH
Protein: asparagine--tRNA ligase (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (Q584F6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Structure-specific endonuclease subunit SLX1 homolog
- Crossover junction endonuclease MUS81
- DNA repair protein, putative
- proline--tRNA ligase
- Tyrosyl/methionyl-tRNA synthetase, putative
- DNA repair protein, putative
- glutamate--tRNA ligase
- leucine--tRNA ligase
- isoleucine--tRNA ligase
- methionine--tRNA ligase
Sequence:
MVLMRKFRCHGGVQCNCALHCFYFYRCPLLCTNIPIRTAAVLSSLRRSSPLLSDPYESGTKKTFSPRRAFIHTTERSKLMSEEIITKLREVVGLDEKNAKDLSTKPERVTDLLEFFGVQGITAASPREQKVMMFNIWTKVKLSEHRDHIATYVKNNKLDSTQKVDAAVRFVNALKANAAFEVAKFEEECGVGVVLSRDDTVRLVKEALEAEDPKVLKASWVKNPNMLIGKVKRAKGLQWADISVVKSAVEEMVPPMIEGVVLEEAPSKPKQAAPSAPSGKGAGGAQQCPRNDDWKNVVDTKKRNLIGDLPKCKEGEIVHVIGWAHRVRHQSRISFVVLRDGSGYIQVVFGGETEPFHRETSLAIRGRLKHEPKAKAELQPPYELHVEEYAIIGNSDGSIENVITAESSPDKLLDDRHLVIRGTYGSTTLKVRHELIRAFREYFWSKGMYEVTPPTLVGTQCEGGSTLFDVMYYGKKAYLTQSSQLYLEACTASLGDVYCLLSSYRAEKSKTKRHLSEYTHLEVEYAVCNFEEMLTYIEDLIVSVFNMVIERVGDLIAFMNPKQLVDPNGNPRDPKNWKLAPKKPFRRLKYADAIKFCNEHNILNPETNEPFKFGEDITDQPERAMVGMIGEIVLMTHFPAEMKSFYMARDDHDNRLTESVDVLAPGIGEVVGGSMRMWDYDELMEAYKREGLDPEVYYWYTEQRKYGSTPHGGFGLGLERLLVWLLDLDSVRDACLFPRYMGRCQP
Protein: Zinc finger protein lsy-27 (O45526)
Organism: Caenorhabditis elegans
Function: Involved in regulating left/right asymmetric differentiation of the gustatory ASE neurons. Plays a role in modulating expression of LIM/homeobox protein lim-6.
Interaction partners:
- One cut domain family member
- Putative T-box protein 36
- Zinc metalloproteinase nas-17
- FLYWCH transcription factor 3
- Nuclear Hormone Receptor family
- Homeodomain-only protein
- Zinc metalloproteinase nas-19
- Forkhead box protein pes-1
- Probable histone-lysine N-methyltransferase lin-59
Sequence:
MTSIHSPVTRKEDTELKRPDLRGKFVCSSCSQNFQHSASLNRHRQLMHSNEHTCMMCERALNQKETIREHMRNEHNLAQVFTCGCCNWTFASKRQLTEHTKCIQGTGAPGDTIPIAKSINAPGSLIQSTIQGTPPVVKTGRKRPMGGSLSPSSSVSTSISSRDASGSPPPTEEEAERKVLFDNAVDTILQSKFFTYQQITEVDTWVKIIESANTLADTLQRIKKSQKVKAEGPAVESKMIPEKHVKQEIE
Protein: Auxin-responsive protein IAA19 (Indoleacetic acid-induced protein 19) (Q6AT33)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Auxin response factor 11
- Transport inhibitor response 1-like protein Os05g0150500
- Auxin response factor 15
- Auxin response factor 9
- Auxin response factor 7
- Auxin response factor 3
- Auxin response factor 14
- Auxin response factor 2
- Auxin response factor 1
- Auxin response factor 16
Sequence:
MPPPLEARDYIGLAASPASSSSSCCASTPVAEVVGAHLALRLGLPGSESPARAEAEAVVVDAALTLGPAPPPRGGAKRGFVDSLDRSEGRRAAATAGDDERGVREEEEEEKGLGEAAAGAPRAAKAQVVGWPPVRSYRKNTLAASATKTKGEDQGKSEVGCCYVKVSMDGAPYLRKVDLKTYSSYEDLSLALEKMFSCFITGRSSSHKTSKRDRLTDGSRADALKDQEYVLTYEDKDADWMLVGDLPWDLFTTSCRKLRIMRGSDAAGMAPRSLEQTGQNK
Protein: Protein Wnt (Q3L251)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
Interaction partners:
Sequence:
MLDGHVLLGWLSSCALLGLLACTPRPSAAYFGLTGNEPLTILPLTSEMEEAAVKAHYKVCDRLKLEKKQRRMCRRDPGVAETLMEAISMSALECQYQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHAMAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSNKFVKEFLGRKPNKDLRARVDFHNNLVGMKVIKAGVETTCKCHGVSGSCTVRTCWRQLSPFHEIGKQLKQKYETSLKVGSTTNEATGEGDISPPKKSIPGHSDQIPRTTDLVYIDDSPSFCLMSRYSPGTSGRKCYKDKNCDSICCGRGHNTQSRVVTRPCQCQVRWCCYVECKQCTQREEVYTCKD
Protein: Antitoxin Rv0909 (P9WJ07)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv0910.
Interaction partners:
- Toxin Rv0910
- Phosphate-specific transport system accessory protein PhoU homolog 1
Sequence:
MGILDKVKNLLSQNADKVETVINKAGEFVDEQTQGNYSDAIHKLHDAASNVVGMSDQQS
Protein: Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase) (Q6PG34)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q5VV42}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- FTO alpha-ketoglutarate-dependent dioxygenase.
- Uroporphyrinogen decarboxylase
- tRNA methyltransferase 10 homolog A
- tRNA dimethylallyltransferase
Sequence:
MMALVCDTAVDDIEDMVRITDVTPLQRQAARKSVVPRARKHKQETGEQMQTDSVIPGMQKVWLKTWGCSHNSSDGEYMAGQLAVAGYQITEDSSDADLWLLNSCTVKSPAEDHFRNAIRKAQEQNKKVVLAGCVPQAQPRMDYIKDLSIIGVQQIDRVVEVVDEAIKGHSVRLLGQKKEKGKRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGDLASYPVEELVERVRQSFQEGVCEIWLTSEDTGAYGRDIGSDLPTLLWRLVEEIPEGAMLRLGMTNPPYILEHLEEMSRILQHPRVFSFLHVPLQSASDSVLMEMRREYCCADFTHLVDYLKERVPGITIATDIICGFPGETDEDFEQTLALVRRYRFPSLFINQFYPRPGTPAALMQQLPAHVKKQRTKELSALFHSYRPYDHKMGEQQQVLVTEESFDSQYYVAHNKFYEQVLVPKRPEYLGKMVQVEVYECGKHYMKGRPLEEAPLRTAYTTAPLLKGQVSGHTQAGVCEPQCWMPDGMRILAVVLLLSAVLLALLMEKLL
Protein: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (Q9VR31)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Protein farnesyltransferase subunit beta
- Geranylgeranyl transferase type-1 subunit beta
- Quemao, isoform A
- CAAX prenyl protease 2
- Alkyl transferase
- Farnesyl pyrophosphate synthase
- ditrans,polycis-polyprenyl diphosphate synthase [
- All trans-polyprenyl-diphosphate synthase PDSS1
- CAAX prenyl protease
- Decaprenyl diphosphate synthase subunit 2, isoform A
Sequence:
MGDSSDEEYLGTDWLAYSERSDWEDVQPLAQDDGPNPVVSIAYSQKFREVFDYMRAIIARGEKSQRALDLTTDALRLNPANYTVWQYRRDVLRELKADLYAELDYLTEVIGQNSKNYQVWHHRRVIVEMLNDPSNELELTENALVNDGDAKNYHAWQHRQWAIRSFNLYDDELSFVDRLISEDQRNNSAWNQRFFVIKHFGFTPELIQRELSYTMNRIRIIKNNESAWNYLVGVMRQGDSGNALLSSYPDVVDFVEELYQAGNRSPYLLAFLIDLYQEQALQLKASDSDQLARKVYGLCEDMATKHDVIRRKYWQYVANHLKNQLSTVEQK
Protein: Chemokine CK-1 (Q9PT04)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MISCRVCVLAALFSLLIITLIPTTQSADCCLKFTRRPVHCRWLKGYTFQDITSSCDLNAVIIQNLRNKFVCADPSQDWTKRVQRCLRKRQEKKSQLKKRV
Protein: 17.6 kDa class I heat shock protein 1 (17.6 kDa heat shock protein 1) (AtHsp17.6A) (Q9XIE3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possesses chaperone activity.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Heat stress transcription factor A-2
- Chaperone protein ClpB1
- Heat shock 70 kDa protein 4
- Heat shock protein 90-1
- DNA ligase
- Heat shock 70 kDa protein 5
- Protein HEAT-STRESS-ASSOCIATED 32
- Heat shock 70 kDa protein 8
- HSP20-like chaperones superfamily protein
- Transmembrane protein
Sequence:
MSLIPSFFGNNRRINNNIFDPFSLDVWDPFKELQFPSSSSSAIANARVDWKETAEAHVFKADLPGMKKEEVKVEIEDDSVLKISGERHVEKEEKQDTWHRVERSSGGFSRKFRLPENVKMDQVKASMENGVLTVTVPKVETNKKKAQVKSIDISG
Protein: Large ribosomal subunit protein uL16c (50S ribosomal protein L16, chloroplastic) (P0C442)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Large ribosomal subunit protein uL14c
- Large ribosomal subunit protein uL3m
- Large ribosomal subunit protein uL22c
- Large ribosomal subunit protein uL22c
- Small ribosomal subunit protein uS12cz/uS12cy
- Large ribosomal subunit protein uL2 C-terminal domain-containing protein
- Large ribosomal subunit protein uL22c
- Large ribosomal subunit protein uL2cz/uL2cy
- Small ribosomal subunit protein uS11c
- Large ribosomal subunit protein mL46
Sequence:
MLSPKRTRFRKQHRGRMKGKSYRGNCICFGRYALQALEPTWITARQIEAGRRAMTRYARRGGKIWVRIFPDKPVTIRPTETRMGSGKGSPEYWVAVVKPGRILYEMGGVSETVARVAISIAASKMPIRSQFLRLEI
Protein: Bloodthirsty-related gene family, member 1 (E3 ubiquitin-protein ligase TRIM39) (F1QYX5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Interferon regulatory factor 3
- E3 ubiquitin-protein ligase TRIM23
Sequence:
MSFPGEFLSEEQFTCSICLDIFTNPVSTPCGHSFCSSCISSYWEGQGKTCFCPLCKESFRKRPELHVNHTLKEITEQFKRMAETTVSVPKTATTDSPPNPFSAQKPGVQQRPVELPKGLFQEMKTRMQRSSSTSSSNEPLASGDPQSLPNVKMPRRNFSVTAAGSNGPQCPNHGYSLELLCKTDLMCICAVCAESEHYGHTVTEAKREMNIRKSQLRILEVELQGLITVRERKIEEIQTSLAEIQVNAEREKAGTISMFAELMKSVEKSQAELLEVVEMGQRAAELRSQAFIREVQTEISDLKNRCSTINQLTQSQDHLTFFKTFSAHTSLPVMKSWAEVALTPDPTAGVVLRNVSQMVEEVRQGLRRLSEICLHPSTERSLGVYQQSVWRAPGFAMDVTLDKDSAHPRLVISEDGKQVLCSDRYQNVPDTLERFDRVVCVLGRQGINSGCHYWEVLVSDKTDWDLGIAARTINRKGKIAANPANGFWFLSLRDKQDYVFRTEPSTPIIVNPKPQRITVSVDYERGQLSFYNADTKTLIFTYTDSFSETLYPFFSPCTNKSGKNEAPLIICPPFVADPSWLE
Protein: Defective proboscis extension response 12, isoform E (A0A0C4DHB6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPMVPPRLLLRLRRPLHLMELRILLLCLPTLLLATTLEPDQKSILTDNDWKKLWMRGGINGDSKLDNNLDSSDSPMFEDSENQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQVTDSGNYTCSASNTEPASIYVFVSKGDNMAAISRRKTSSADRLTHIFRSMLAPCLLLNTVVVRHIFLT
Protein: NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit 6) (NADH-plastoquinone oxidoreductase subunit 6) (P0C329)
Organism: Oryza sativa (Rice)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MDLPGPIHEILVLFGGFVLLLGGLGVVLLTNPTFSAFSLGLVLVCISLFYILLNSYFVAVAQLLIYVGAINVLIIFAVMFVNGSEWSKDKNFWTIGDGFTSLVCITIPFSLMTTIPDTSWYGILWTTRSNQIVEQGLINNVQQIGIHLATDFYLPFELISIILLVSLIGAITMARQ