wanglab/gogpt-training-data huggingface dataset:
Protein: Adhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3) (O60242)
Organism: Homo sapiens (Human)
Function: Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21262840, ECO:0000269|PubMed:22333914}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- E3 SUMO-protein ligase RanBP2
- Complement C1q-like protein 3
- C1q-related factor
- Metabotropic glutamate receptor 8
- Engulfment and cell motility protein 1
- Ran GTPase-activating protein 1
Sequence:
MKAVRNLLIYIFSTYLLVMFGFNAAQDFWCSTLVKGVIYGSYSVSEMFPKNFTNCTWTLENPDPTKYSIYLKFSKKDLSCSNFSLLAYQFDHFSHEKIKDLLRKNHSIMQLCNSKNAFVFLQYDKNFIQIRRVFPTNFPGLQKKGEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLKSENGRTESCGIMYTKCTCPQHLGEWGIDDQSLILLNNVVLPLNEQTEGCLTQELQTTQVCNLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQEQADAAKFMAQTGESGVEEWSQWSTCSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAESRECYNPECTANGQWNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDYLMSMVWKRTPAGDLAFNQCPLNATGTTSRRCSLSLHGVAFWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTKTLLDLTQRKNFYAGDLLMSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEKWEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINFPMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNYTVINSKIIVVTIRPEPKTTDSFLEIELAHLANGTLNPYCVLWDDSKTNESLGTWSTQGCKTVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTPSVTLIVGSGLSCLALITLAVVYAALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVLTEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQGFVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVLHKDIGPCRAATITGTLSRISLNDDEEEKGTNPEGLSYSTLPGNVISKVIIQQPTGLHMPMSMNELSNPCLKKENSELRRTVYLCTDDNLRGADMDIVHPQERMMESDYIVMPRSSVNNQPSMKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLEQHLAPQEHMQNLPFEPRTAVKNFMASELDDNAGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQELNQKFQTLDRFRDIPNTSSMENPAPNKNPWDTFKNPSEYPHYTTINVLDTEAKDALELRPAEWEKCLNLPLDVQEGDFQTEV
Protein: Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6) (Keratin-36) (K36) (O76013)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHVQSRPL
Protein: Argininosuccinate synthase, chloroplastic (EC 6.3.4.5) (Citrulline--aspartate ligase) (Q9SZX3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Ornithine transcarbamylase, chloroplastic
- Carbamoyl phosphate synthase arginine-specific large chain, chloroplastic
- Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic
- Argininosuccinate lyase, chloroplastic
- Carbamoyl phosphate synthase small chain, chloroplastic
- Aspartate carbamoyltransferase, chloroplastic
- Arginine biosynthesis bifunctional protein ArgJ
- Acetylglutamate kinase, chloroplastic
- Acetylornithine deacetylase
- Probable amino-acid acetyltransferase NAGS1, chloroplastic
Sequence:
MAEISATSFPSSSSSALVIRSSHNGSLKCQNVAVPKTTSQFQELSLKRSQLVGNAVVTGHVTGSRSCKNQAIRAVLSGDGTALTTDSKEAGLRGKLKKVVLAYSGGLDTSVIVPWLKENYGCEVVCFTADVGQGIKELEGLEQKAKASGASQLVVKDLTEEFVKDFIFPCLRAGAIYERKYLLGTSMARPVIAKAMVDVAAEVGADAVAHGCTGKGNDQVRFELTFFSLNPELKVVAPWREWEIQGREDAIEYAKKHNVPVPVTKKSIYSRDRNLWHLSHEGDLLEDPANEPKKDMYMMSVDPEDAPDQPEYIEIGIESGLPVALNGKALSPATLLAELNTIGGKHGIGRIDMVENRLVGMKSRGVYETPGGTILFAAVQELESLTLDRESIQVKDTLALKYAEMVYAGRWFDPLRESMDAFMEKITETTTGSVTLKLYKGSVSVTGRQSPNSLYRQDISSFEGSEIYNQADAAGFIRLYGLPMKIRAMLKKIS
Protein: Major centromere autoantigen B (Centromere protein B) (CENP-B) (P07199)
Organism: Homo sapiens (Human)
Function: Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00320, ECO:0000255|PROSITE-ProRule:PRU00583, ECO:0000269|PubMed:18072184}. Chromosome, centromere {ECO:0000269|PubMed:18072184}.
Interaction partners:
- Histone H3-like centromeric protein A
- Centromere protein C
- Centromere protein S
- Centromere protein H
- Centromere-associated protein E
- Centromere protein I
- Centromere protein W
- E3 ubiquitin-protein ligase TRIM21
- Centromere protein F
- RNA-binding protein RO60
Sequence:
MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS
Protein: Uncharacterized methyltransferase C25B8.09 (EC 2.1.1.-) (Q9UTA9)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable methyltransferase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MIGRTFKTDIADYETARPDYPPQITEWLNDEFSVNETSTILELGAGSGKLTPRIIASQPKEIIAVDTYVEMLDVLKKKFPNVDCRVGSAMAIPLEDESVDLVACGQCFHWFANEEALKEIYRVLKPNGKLALIWNIRDNSVPWVEKCSQLLEKCRGGPLNMFEKAAELFPGYGFTELKQSLFTSAKKYSIEDLHRLMNSFSSINRLPVEEKEKMHAELDEIIKTIPRAQNTDQVDFNILTVAYSSEKVPIN
Protein: Bacteriochlorophyll synthase 23 kDa chain (4-vinyl reductase) (P26169)
Organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Interaction partners:
- Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
- Light-independent protochlorophyllide reductase subunit N
- Light-independent protochlorophyllide reductase subunit B
- Magnesium-chelatase 60 kDa subunit
- Bacteriochlorophyll synthase 33 kDa chain
- Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic
- Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein
- Geranylgeranyl diphosphate reductase
- 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase
- Chlorophyllide reductase 52.5 kDa chain
Sequence:
MSGAAPAPQDDEPRIGPNAILQTIGVLDRHLGRAERDRVMRLAGVPVPPPDSGMLPESQCRAVHQALRVDQGEAAEGLLWLSGLATGDYILANRIPGFAKAIIRVLPGFLGARLLAAAITKHAWTFVGSGRFRVESFRPLTFRIDDNPLRADAAERPSCFWHAAVFERLFGTLVWPEVTVEEISCASVSGGPCLFVLHPKGKKTAMPSSVHSG
Protein: MNAT1 component of CDK activating kinase (H0YJF2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
VFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGGFDTISLI
Protein: Serine/threonine-protein kinase sgk-1 (EC 2.7.11.1) (Serum- and glucocorticoid-inducible kinase homolog) (Serum/glucocorticoid-regulated kinase 1) (Q2PJ68)
Organism: Caenorhabditis elegans
Function: Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Essential role in regulating development, stress response, and longevity. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their function. Promotes the cytoplasmic localization of the transcription factor pqm-1. Plays a role in the intracellular trafficking of proteins such as mig-14 to the cell membrane, and this may be through positively regulating ceramide synthesis. Acts downstream of rict-1 to regulate fat storage, size, development and vitellogenesis. Downstream of age-1 and together with akt-1/2, promotes cell survival during embryonic development. Plays a role in maintaining the gonadal basement membrane through antagonizing akt-1 activity. Does not appear to play a role in immune function.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15068796, ECO:0000269|PubMed:26115433}. Nucleus {ECO:0000269|PubMed:15068796}. Apical cell membrane {ECO:0000269|PubMed:26115433}. Note=Localized both in the cytoplasm and in the nucleus in neurons, exclusively cytoplasmic in the intestine. Localizes to the apical cell membrane and diffusely throughout the cytoplasm in intestinal cells (PubMed:26115433). {ECO:0000269|PubMed:15068796, ECO:0000269|PubMed:26115433}.
Interaction partners:
- Forkhead box protein O
- Target of rapamycin homolog
- 3-phosphoinositide-dependent protein kinase 1
- RICTOR_N domain-containing protein
- cAMP-dependent protein kinase regulatory subunit
- Phosphatidylinositol 3-kinase age-1
- non-specific serine/threonine protein kinase
- DAF-15
- Target of rapamycin complex subunit lst8
- Protein skinhead-1
Sequence:
MGSMYYNESRMVRKDEVTCNVIIGDDKKTVVYALRIGNGPIMQKTFEEYERFFTTEKDMIPATIFTAPKKKFLQADSKFYEKRRVWILVISQHLVDNNLRSEDVRRFFHLESPDDDENNVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEIQIDPSSLAPQQLAVTHRDHDFENFTFVDTNRVLV
Protein: Fatty acid binding protein 4, adipocyte (F1MHQ4)
Organism: Bos taurus (Bovine)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPTLIISLNGGVVTIKSESTFKNTEISFKLGQEFDEITPDDRKVKSIVNLDEGALVQVQNWDGKSTTIKRKLVDDKMVLECVMNGVTATRVYERA
Protein: Peptidase inhibitor 15 (PI-15) (25 kDa trypsin inhibitor) (p25TI) (Cysteine-rich secretory protein 8) (CRISP-8) (SugarCrisp) (O43692)
Organism: Homo sapiens (Human)
Function: Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:8882727}.
Interaction partners:
- Trifunctional purine biosynthetic protein adenosine-3
Sequence:
MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK
Protein: Cep192 protein (Q6P2K8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MNDLIPGKESKVVFSIRNTGSRAAFVRAVCFKESQRKVLLDPKVLRIFPDKFVLKERTQEHITLVYTPSSRKNGEKPATELLTVYMFGGDEISRQQYRRAQMHTPGILKQILPEHSVLQHIDFTEAFQDEPLIDEVCDLPQRPNDIELFYGSMRKITLSVIGEFRGTICSREFLQPSSSAESKSNFSSDSKTSGKQSGNVLLDVLPVKGPQGPPFLSQSAHPAQDTAASEEGWAVHPEHLILVAPSSCDLAKTGCFQIINNSVILLKFELYWPAHCLTVTPQHGCIMPESKIQILVSPNFSVSTKESVCPWTGLIYIHCDNGQKKIVKVQIREDLTQEPLPHLPSSGTSGILAPAPEPSISRLTKLITKPPSTKVEIRSKTVIFPPTEPGRTSENYLELENCGPTDVKWHLSSFAPPYVKGVDETEDVFRATYTTFRCSPISGTLEGHGIQKVSIIFLPRDKGNYAQFWDVECHPAKEPHMKHTLRFQLSGQSIRAENDPEDSCSSRDALIKVDTAVTSRRRAVSETAAHTPGQLNSSHHGVYAPKDVYTFLPTKLGESRTLKINLRNNSFSTHALKFLSPREPFHIRHSKYTLRARHYIHIPVHFRPEAVGRFEALLVIQTDEGKSIAIRLIGESLGKS
Protein: Uncharacterized protein At2g41960 (P93750)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MNKYKCKTMPGLTTHMNEHYSSSGFWSEDDDGLTYDQLDQFWSELSSKARHELLRIDKQTLFEQARKNMCCSRCLGLLLEGFAQILSAGRAAYEKRMMGPSKDNCKSNGTRKCTVAYQSPPVHRWGGLTTTRSGCITLLDCFLTAKTFKGLQNVFESNRARERERELLYPDACGGGGRVWLSQGIAGFGKGHGTRETCNLHTTRLSCDTLVDFWSALEEHSRQSLLRMKEEDFVERLTYRFDCKKFCRDCRRNVIREFKELKELKRIQRDPRCTDWFCVADTAFQYEVDIDSVRADWSQYFTENAGYHHFEWAIGTGEGESDILEFKYVGNDRSARVNGLDLRGLHECYITLRAFKKNGRPSEISVKAHALRGQQCVHSRLVVGDGFVSIKRGECIRMFFEHAEEAEEEEDEVLIDKDGNELDGECLRPQKHAKSPELAREFLLDAATVIFKEQVEKAFRDGTARQNAHSIFVCLSSELLEQRVHIACKEIVTLEKQNKLLEEEEKEKREEEERKERKRIKEREKKLRRKERLKEKEREKEQKNPKFSDKAILPIMSREEEGSRNLDEDTNNTIRCEESGIENGDVDLSSPGSPDDQDEECLDGCISPRVETHSCDSTDKEIIDHEDENGCFTPRPAHKTARLWKEVQTDHSLRLSEKRRFTEKTSFVSSSEAGYCNDRLEMSSGHFNGSDKNVRVKASKAGGSPNSSRSHEEFQCSDGRTGERYDYHSCSCKPINGYREKVESNTSATRGMREPKSVFKSDSDLDVSKLNRANRYTQSGYRREIRSKMNNSRNACKMDPVNVRKVLDSVEPKHSRNSSTSDVLSLTTYKAEEIKDVSPTVKPAGTPSLCKATDKLGNGSFNNSTEVDKKMEVHITLKNDYLYSKDPMMSRSSSSNNGNIESSSMSDSEVASQQSEGRENLVDTQNDMPDCHEKMVEKVTEMSMDERDVLKIKNISNLPADNGESKLSGTPFMVPSQNMENMVPGLNTGSYLSQPQNMILPQMLNQSIPLPVFQAPSTMGYYHQAPVSWSSASTNGLMQFPHPNHYVYTGPLGYSLNGESPLCMQYGTPLNHSAAPFFNSGPVPIFHPFAETNTMNTVDQAQPLEPLEHSFLKEANERRFNEMPLMETPRKRCPQTDSDENFSLFHFGGPVALSTGSKANPARSKDGILEDFSLQFSGDHVFGDPTGNSKKEKENTVGEEYNLFATSNSLRFSIF
Protein: Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1) (O15126)
Organism: Homo sapiens (Human)
Function: Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15840657}; Multi-pass membrane protein {ECO:0000269|PubMed:15840657}. Recycling endosome membrane {ECO:0000269|PubMed:15840657}; Multi-pass membrane protein {ECO:0000269|PubMed:15840657}.
Interaction partners:
- Intersectin-1
- Synergin gamma
Sequence:
MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGGVKMPNVPNTQPAIMKPTEEHPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSARAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNQNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAASSAAQNAFKGNQI
Protein: Uncharacterized protein (Q57ZF7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
METQVPQNVMEDAIAVWNRLQCWGNASNYLLALNNPCMQHQKHGVTKWDPYSIRLARRVVAVVERLDNHREKSLGLGATPREKLLALAEVVRLCLESFDPLGTPLVQGAAFPFKTPSSFLSPSPPVEWERAVDKRVVSGTMIMEGLHILTYPSVQLRIEASVEQLLQHIMEEFNGGSKRTMRHSPEELRALRATTMLLEDFDALYKRIVCVFPCVRMMGSPHIPVALLPIVIKLYYKMAEWVRDAEVTGELNSFAQITVFKKKKLFVKMRRGDKNVPWGLQFNDEGRVVQVNPSVRSGSHAAEVLHGLTQFFKKGLSIVELNSQPVSFANLTAKQATDKLHFWTIDDSRLSLTMQDDHTTPPLLEQLAFFVVPGAKKQCGTLRDGDDTCATLVLHRELCGISWDIRLTSELCVVDVPTSILSKEAATFFKTHHKQLRIGAINGVKVTRAYQVEALSQFVNTIVIDFYKVPPPETVPAQVKPKRVPALKSDTKNTPSQHTSVVVTATAVAAPETVKRIANDGKEQQLREVQTSKKKIEDSSPLDKAGGKSNSTTAIVHAKEAPLVLVSTVAEKLRSIARAGSIPGKNGANGFLEDAERRAVSKNDEYRSATKQNEVRGNLDGDVTTSLTDTVMVLDMDGAEPLTFPNNVTINMLTPEEMVVQRPSCEKKWGFSLETEGMYPKKTIHMSGLPRMLDEQWHHPFSKLFRSRKGEWRIASVNGTPASQLPEVIDVMKHALKMQIKFIRRW
Protein: Dorsocross1, isoform A (FI01016p) (Tbx6 protein) (Q9U8L5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00201}.
Interaction partners:
- Dorsocross3
- Dorsocross2
Sequence:
MLSMQELMDMRMQQQLAHEIYRQQIMQRIPDPFPSMLPFNMPHQQPHMMLPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASMHKYQPRLHIIRSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQDSTGSVSPAYYGATHPVANPMSPYLRHHLSYGPSGAAGLPPSIAAAYFGGVPPQILPMPPATYAPTVAPVSPVASQPVGSSTPTTSPRPSTSTKRNSFSISAILAY
Protein: Focal adhesion kinase, isoform D (EC 2.7.10.-) (B7YZL9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Paxillin, isoform F
- Vinculin
- Breast cancer anti-estrogen resistance protein 1
- Tyrosine-protein kinase
- RB1-inducible coiled-coil protein 1
- Growth factor receptor-bound protein 2
- Rhea, isoform B
- Epidermal growth factor receptor
- Integrin beta-PS
- Zyx102 protein
Sequence:
MNTAGATSQPPPTKNEINSEEYLIHVHMPNKSFKAVRFNVKETVFHVIRRTVEDLGTDGRTPSIQRYACRMLNMITKEVIWLARSTSMQKVLSHILTPGCSNVDCPNNQSELDEVLLEHGRRITDNRVWRVELRVRYVPNNIQELFEEDKATCFYYFNQVKEDFIQANVTAIDTEVAVQLCCLGIRHYFKNITVKAPDKKQHIDYIEKEIGFKSFLPQSVIATSKPKNLKKLIQVGYKKVYNYNDIEYLTRFFDLLKNIYLTNFEQFSVTLSSAWNISGILHVGPHIGISYQTHPQASLKNVAQFKDVVSIKTCTLPKEKLSKSGENTTEPELQNFNCNCQKIKTQIKISASNNVEDLVITCNGINTAESIADLIDGYCRLLSKDLEFTIWHRETNASNEDSAKALPNDATLGSNKSTSSQGKPMLTDDYAEIGLLEGEGDYSTPTVRNYELDRALITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEILIEDSINSSETLKREQRKVASMSWIGSDDIDIPPSKPSRVMHDPDITGLMPETTGLPQTYIIAQNPAVLAKLMMENQKRGINPAAYTTPASVFNTLAVGLDDSNPNVSLKTTKLPAADLLKLDPIAESERLRSQFSANSSASQLANPLTASVNPHESLNSHQAGMFTGSLPSKSSFVVCPPQTEEHMQAENISNPSVSKVSGYSLYGSLERHQPPPAKAMHSKGGSLERHQSLMSAQNLVFYNTKPPPNCTNTAERSRSMERNTYFHAYRQQMKTSIECEALPEEIYDFGGIGLKTCVSARQQPKFSPMVNVRPAELGQVQNTDCMGLQQNIPMDSFGVISPHNLDESLRHQREMERQWMTSGPQSITVNPNISISEGAACLATLQAEAMGNQGIHNVLGEKLRQQQKDSNSDSEWLIQEELLRSCSIPQGSLNDHQAQMFKLDFMSAGPSSLPDCSNSSSRPMTPNANLSSLKSNHSSADHLSSLTSAEEQMGSNARNLGSAVPSRPPNRADDEVYCATTLVVKSIMALSQGVEKANTEGYLELVKNVGVKLRNLLTSVDKISIIFPAQALKEVQMAHQVLSKDMHELVSAMRLAQQYSDTTLDCEYRKSMLSAAHVLAMDAKNLFDVVDSIRQRYQHLFPPSATKETSCSSSFESTSGSIVAEPVNDLGGYIKTSTSGDLLQNTGIYDNDLHHSFNSQLQLQNPKASIDLSGGGSLQRGMSLGLDTTRSTNEPLRIVEETLGSPGEHMYCNTSALHGHA
Protein: GDP-mannose transporter GONST3 (Protein GOLGI NUCLEOTIDE SUGAR TRANSPORTER 3) (Q9S845)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- GDP-mannose transporter GONST5
- GDP-mannose 4,6 dehydratase 2
- UDP-galactose/UDP-glucose transporter 1
Sequence:
MSTNDEENGTVIEVKNVPEPSPETWYSVFLRQASVYGVAAGYCLSASLLSIINKWAIMKFPYPGALTAMQYFTSAAGVLLCAQMKLIEHDSLNLLTMWRFLPAAMIFYLSLFTNSELLLHANVDTFIVFRSAVPIFVAIGETLFLHQPWPSVKTWGSLATIFGGSLLYVFTDYQFTIAAYSWALAYLVSMTIDFVYIKHVVMTIGLNTWGLVLYNNLEALLLFPLELLIMGELKKIKHEITDETDWYSLQVVLPVGLSCLFGLAISFFGFSCRRAISATGFTVLGIVNKLLTVVINLMVWDKHSTFVGTLGLLVCMFGGVMYQQSTIKKPNATQEAKPQEQDEEQEKLLEMQENKESNSVDIKETLKSEEKL
Protein: Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (P62630)
Organism: Rattus norvegicus (Rat)
Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P68104}. Nucleus {ECO:0000250|UniProtKB:P68104}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P68104}. Cell membrane {ECO:0000250|UniProtKB:P68104}. Note=Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens. Localization at the cell membrane depends on EEF1A1 phosphorylation status and the presence of PPP1R16B. {ECO:0000250|UniProtKB:P68104}.
Interaction partners:
- Elongation factor 1-gamma
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL4
- Actin, cytoplasmic 1
- Glial fibrillary acidic protein
- Actin, cytoplasmic 2
- Elongation factor 2
- GTP-binding nuclear protein Ran
- GTP-binding nuclear protein Ran
- GTP-binding nuclear protein Ran, testis-specific isoform
Sequence:
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK
Protein: DNA 3'-5' helicase (EC 5.6.2.4) (E9ADR1)
Organism: Leishmania major
Interaction partners:
- General transcription factor IIH subunit 4
- VWFA domain-containing protein
- [RNA-polymerase]-subunit kinase
- DNA 5'-3' helicase
- Putative DNA-repair protein
- TROVE domain-containing protein
- TATA box-binding protein-like 1
- DNA-directed RNA polymerase subunit beta
- Putative DNA-direcetd RNA polymerase II,subunit 9
- Putative RNA polymerase-like protein
Sequence:
MNIGDSGNIFVEKAHPAYAHVIDFLISCCEPVSRTQHMEQYRMDSSSLSSATAEGTYSLAMIENVLRHFRLNAAQELPVDLERCAALERLASALDESTESAEVDGSRVSQEALATTTASSSFDARIPLPRCLCDVDLTGTILASLNRTSADDAPSPAVTAHHVGNDSLETLVKREKVEEEEMGDRLSAGGAAASALKTVSSRSAAPSGSPTSRLLQLFRPLLPTPASAAAPTHSPTTRSQLEQGAPIAARPLISLAVVRPADVRRPLPESLAQMLEEEENASRVQIVLQPRLRRFHQFEASRGASFASTTATSRATVSKERNGAATGALAERDDQQLFYFVQSRERAHLEHVLPALKEFLEPVVICGAERWIVSDVDRTPLGNTKGIGDAERLARDAGRPAVLRLLYEPPRVGTQYEKAEATPSASRFLYKCQVRDGKLREVKECLFSKFDIRADCYYDYMQDHTLYVPNLSLASHVRLRPYQVASLERFRRGRKAHQGVIVLPCGAGKTLTGIGAAATMQTTTIVMCINHMSVFQWQREFLRWTNLAEEEVTVCTAKVKQRPGKVFITTYSMVVAKRGSADGAAAEESRAILQVMTAQPWGLLLLDEVHTALAHHFQDVLNTIKYKCVLGLSATLLREDDKIGDLRHLVGPKLYEANWLDLTRAGFLANVECAEVQCPMPPLFLQEYYGIQRTRALLGAHARRNHRGGCGGNGKRCRESVFQDDEDAGEDGDSDGEDNGARGGRGRGHDAYGPLTSRSLRLASCNPYKLWCAQALLAFHQQRSPPDKVIIFCDYLADVRFFAHHLHLPFMDQRTSEAERTNLLQYFQHSDGVNAIILTRVGDVALDLPCASVVIQVSGLGASRRQEAQRLGRILRPKPPSLDNTCAYFYTLVSQDTADVSTSYKRQSWLRDQGFAYRILHCDRVLSEFARVGGQPCCVGPPQWWYQTHNTASATPSSETAAAVDVGWVHYDGFYWAPFSADAAALIEAAFQHGRATCIVRGSELGRGTPRPSSEELGRYPLLSFESWKVTFSSVDAPQTFGTVLIGEGAPSSPLRERRVRRGCLDRSHRCIPATADQESRCISFARNTVLRARDTRGSDAVTEVE
Protein: Lethal (3) persistent salivary gland 2 (Q9VRM6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSQAAGGSAVGMEQPATGKQLKPPEDLQDNDTNSLEPGEVVTPPHYHPSSPAVKKHLSKELMISKTLRKLPVSVVEQARKENGSGGTPNAQAEDADDSEGLYSESDSSGEDLKNVEDVQKARKEKQEEAAAATLPQAPPTPFLGINPLRFHMRAPCFEFPRMGFMPRMNRGGPRGMRPTFFGRPPAANRMGAPMMGGLPTQGPPPGAYAPQNPPPTGINSNSGRCKRLQSDVIWTALQPPVSFVFNLVSECSNTKHENCRTKAETTDHNSKESKLPSETKSTEPLIENNRSRELPQHKNYVRGKTSNRSHDRTQNRGRTRERSKESHGKSTENSKNKDEGRGKGRERDLFRRKSRERSQDKNLNRAKSMNLSKEKDEVGGEPRNTASGKSQERDQSRGKTKDRSRERDRTRNKTREKSQARDQTRSKANDAEHTRAKSRKRSSSRDKRREKSKEKLGDKEKNEDLSKEKLEGKSTEHSEKRNESKVKNKDTNEENANKKLRERSKDRNHSKERLHERTQNKSEERKPEAKKVRNAIENSKEAPTDRKKDKLLGPLGEKTDERSKDKQIKRSREQSVTKCPKESGKDTLMEHPPQENGLDGSKRSSMPHESFSESAKTREHASRRKNQTLSPWGSREGTPPMTPPQVQIPQTPIVDIANPKDFDIFADSPPRVNTAVSAPAATIERSTTPPLKSSIPIVPIAKADKLAPLLKASEIHSRIGALLEESDLHLDNLLATKEQLFRRTNEYKERKEAPKEIKAEYLPNSRHNRSATGRAEVEHHKSQPRHINPFKRESVLSGRKSSSRPSSKERRFQRHDSEVENWDRDLELERNQLNGSQLTGFQPRKSDEYTKFSIKKEKDLTPPPLQTNFTRTTIKIERNATPPRHMEHDVLVRNGAVATNAPPPAKEQESPDTDDYIDNWENDDSLASMPKNAPPVTPTPAPNANASLNATPLPPVASQFNGDDDDDDSNALWNAKSTPPPRRKNENLPEGNIHELYDKFMNSIKMSNEHLEPETLDTSKNSSLSNSPAEESSSGTETSSTSSSSSETEDDSSSDDDANESSSNDESATTSGNCNTNQDEAAGKEQLQKKNNVSKDLRKLKSLEDNLARIQMMRENYDAGDEISEELLKMESLFLMQRNAIMDKYRKQELKSNSSEDQQPVDEQGTVQAQEVVKETSFPVNSIFSANREAIKLTISPLKLTRKSVIFDKDEADLPETSKAEPPKQTLQKPQKEIAIVKPTIVESRSKPKLRSPPPSSGSRRRSRSRSISRSRARRRGSRTKSRTPSPRRRRLPSPRRVSRYAKRIGGGAVGGTRKGRSHSRSLTRSRTRSRSPSRRRRLPPAGHRKRGSISPIPQKLAGPRSPPPSRRRQSLSRDREREHLSRSRSPLPFKPPSPPMRRSWSKARSPTRRRSFSRSRSRSISPRSRLSAEEAFANYFEENQGMEAAAYYYNMSLMQQEDQNALGEGYDAYAAYMDSAYNMEQAYAQYSEEYSNTYMDYMVEVASSPQAPGSVLRELPMAPMMPVESLAPIAPLEAMPSMAATASGMPVAVQKGNVLEIVPSGEDILEAEENIVPDATDKPVEDTSKPKGKGVNFVDKVLPAYESDNEDRAVVEMAVKRALRKYHESRSQAAAKLQLIRDELLLLPPPPPPPLTTKPANLEKPVLVQKKPKFRYFHFDPFKCAIVKTYTRTLRSAYRPPFDPKHFAMLMKTGRLPQIPPGFLRHRPPFIPAHVDAVTRGAMLKEFFSKHPPPPLAMPMPVPNGMPYYLSGPPPTSSGAAVSPVPVNVLPQPIPVLDGSGYQGYPQSATMVPLPVPVPVPVPLPVPLPVSTDTTPSPALETPYFTPPPLPELPPLPELPSQFTVSSVPTITEIMPVDILQKLGPLPKTLDVDDGGGTASPEDISDDLKEVEAKPAEQHVVGVKPQLLVETQ