wanglab/gogpt-training-data huggingface dataset:
Protein: IQ motif containing GTPase activating protein 3 (Q3UQP1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDIKIGLLVKNRITLQEVVSHCKKLTKKNKEQLSDMMILDKQKGLKSLSREKRQKLEAYQHLFYLLQTQPIYLAKLIFQMPQNKTTKFMEGVIFSLYNYASNRREAYLLLQLFRTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDRSVSIHTDPVHIYKSWINQEEAQTGQRSHLPYDVTPEQALSHSEVQRRLDISLRSLLTLTEKFFVAISSSVDHIPYGMRYMAKVLKTTLEKKFPNATERDIYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGSTLAAPQRHALGAVAQLLQHAAAGQIFSGESRHLRVLNDYLEDLHLKFRKFICRACRVPEPEERFAIDEYSDMVAVAKPMVYITVGELIGTHRLLLEHQDQLAPGHQDPLHQLLEDLGEPPTISDLIGDNIATDGHVDLSRLEVSLTLTNKFEGLETDADHNSNQSLLLSTKQMLADLIQFHPGESLEEILTSSAPREHEEAHRRLMCWRQACDTQKPEPLRRHHSLMAHSLLSLSEKQQRVLRNLRRLQGLGLVRASDCYQGLVDELAKDICNQRRHRQRRKAEMLRLRTTLQGLDAKTIFYEEQGDYYNQYIQACLDHLAPKPKSSGKGKKQPSLHYTAAQLLEKGVLVEIEDLPVSHFRNVIFDITPGDEAGRFFVNAKFLGVDMEKFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLLIFLLNKKFLRK
Protein: Transmembrane Fragile-X-F-associated protein (Q94K50)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MLVQRRVMSWRRVWKSFQAASAHCLLFSFTLLLALKLDHVVSHSWWFVFAPLWLFHAVIARGRFSLPAPSMPHDRHWAPFHSVMATPLLVAFEILLCVHLEDKYVVDLKIVFLPLLAFEVAILIDNVRMCRTLMPGDEETMSDEAIWETLPHFWVSISMVFFIAATTFTLLKLCGDVAALGWWDLFINFGIAECFAFLVCTKWSNQSIHRYSHIPEPSSSSMVVRYLDWNRGLVVTADDEHQQSNRICGLQDIGGHVMKIPFVTFQIILFMRLEGTPASAKNIPILVLFVPLFLLQGAGVLFAMYRLVEKSVLLINSGSGSYGRYFTATSSAREFLGFFQHGARLLGWWSIDEGSREEQARLYSGEATGYNTFSPEVVKKMPKSDLVEEIWRLQAALSEQTDITSYSQQEYERLQNEKILCRVCFEDPINVVLLPCRHHVLCSTCCEKCKKCPICRVLIEERMPVYDV
Protein: ATP-binding cassette transporter abc1 (Q92337)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
- ATP-binding cassette transporter abc4
Sequence:
MKMFQSFFSNYIDINFFRNATLDQCLLLFYLSLFSLTNLFLIQKLFHANHTQHPLKKYFGETCLLEYIQIILSIVSAALSFYLDTNAVWWAIRTITHLEIVGLNILSSLKYGSTLFSWISVANAFGLLLLRLISIYDFLTYSSWSFSVKGGSFLLLLPLAYNITLFLLVIIPLFFPRAWSPTVKFSKVARPSPEQTCSIFSLIFTYGWLNGIIWKSWKKPITLTDVPALPDTECTQIWYSRFAKNDRKSLMHTILLSLKSTILLMVFLSVLVSSTLFVTPLAIKKLLQYLQNPKSDEGNSPFLWVFVLLIGPYLASVVKELYVHVSRRFMLRIKAAITQMIYKKVLTSKTLFVAVDGSKINLDYVYNLLAKDVDNIGEMREFIGIIARAPLEMGVSMYFLYQLLGWSAYVGLLLAILSSSFPLLVASKISRLTSIANTSSDERIRLTTELLKSIKITKLFGWERPMLSRIQEKRSFEVNNMYSLTLFDIIFKSGMKIAPFISMFITFAIYTKIMGHQLTPATAFTSISMFGLLRYQFIWLASVSRQFIQFKVSLKRVDNFVYGNMVNDSSIESSDSFVFENTSLSWSPTPSTALFQLKNLNFTIPRNQFTLVVGSTGSGKSTLAMALLGELHVISGKMTTPSISQRIAYVPQAAWLRNGTIRSNILFGEPYDEERYFQIIKACCLDSDLNSMNDGDLTYIHSNGSSLSGGQKQRVSLARALYSNAEVYIFDDIFSALDVSTSRKIYESCFLSTLLQHKTIILFTHNVSLCLPIAENVIVLKNSTAQLVSPDSIQELVPSTFFSSNTKKDNIEEENLEPHSFSFDSTLASSSDNDEQRDFASNSSIVLLGLHYLKYFGSNKYILGSILLVMMSQVSLASIHFWIALWSGNSLFSLKLPSSFSFLWGYAILLFIYFLMDLSRAITFAKGGRTASENIHDILSERVLYSPLHWFEKTAAGRILNRFSKDMYATDNLLWASLEGMLLCVMAILITMLNVTLVMPIFMVPAAFVSLLVYLHGYAYSKAQKQLTSLQSSRTSPVFTMLGETLGGITVIRAFKKEKIFEHENMAFIDDMIQPLYISFAINRWLAIRTDGISGLVGFSTGLIALLRQNIPPGLVGFSLNSAIGFNISVLVFVRANNEILTYINNFRRLYEYMLLPSEKNESSCLTKPMNKEWPTLGHVSIKNLTVSYSIGQAAVLEDINLEILPKEKIAIVGRTGSGKSTMGLTLLRFTMIMSGAVEVDGIDINSLDLEVLRQRISLIPQDPVLISGTVRSNLDPFEEYGDGELNEILKTASCESLVQASNKNSLDAFAIHLDTPVDSGGVNFSSGQRQILALARALVRKSRIVILDESTASVDDTTDRRIQQMLRAAFKHATVLCIAHRIKTIVDYDKVLVLDSGKTVEFGSPKSLYTQRRAFWKMCKESHISL
Protein: L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (CD antigen CD62L) (P98131)
Organism: Bos taurus (Bovine)
Function: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
Subcellular location: Cell membrane {ECO:0000269|PubMed:1371468, ECO:0000269|PubMed:7694420}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Glycosylation-dependent cell adhesion molecule 1
- CD34 molecule
- CD44 antigen
- P-selectin
- CD4 molecule
- C-C chemokine receptor type 7
- Interferon gamma
- Mucosal vascular addressin cell adhesion molecule 1.
- E-selectin
- CD69 molecule
Sequence:
MLCPWKCQNAQRGLWNVFKLWVWIMLCCDFFAHHGTDCWTYHYSKRPMPWEKARAFCRENYTDLVAIQNKGEIEYLNKTLPFSRTYYWIGIRKVEGVWTWVGTNKSLTEEAKNWGAGEPNNRKSKEDCVEIYIKRNKDSGKWNDDACHKAKTALCYTASCKPWSCSGHGQCVEVINNYTCNCDLGYYGPECQFVTQCVPLEAPKLGTMACTHPLGNFSFMSQCAFNCSKGTDMIGVEETTCAPFGNWSSPEPTCRVIQCEPLTEPDLGTMDCNHPLVDFGFSSTCTFSCSEEAELTGEKKTICGLSGNWSSPSPRCQKINRTISINEESDYNPLFIPVAVMVTAFSGLAFIIWLARRLKRKSKKVSEKHG
Protein: Calpastatin (Calpain inhibitor) (E7ES10)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSK
Protein: LD07765p (Q961D7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNDAMEEMLLRPAIITCPEVRTKPTPPNLSRSKSKASVAVNLGEPPVQIGRDNLGSSESCSSILLDYVNDQSKQLKSDLQAEQSNSLKSMRLKSLLERIEKIRVQLLEELKAGESGASKGDNAQELNNIRQERADILSERTRTLNERESDLQQKEAILEQRLRKFYKETKNAKSSESDKPKSNAKEDGPVEIIIKVRSDGTVKQYVPRTKSKAKTKPSAIDNEKDVPLGSTDSTPRDDEPKPTEQDHGKRPFLQDQRQISIDSNSTAYRSLPPVSYKNMTTAAPPSAPLHPMVVQYINRLLGMTRQNIDEMGVSSSCVTTPSTSVINSLRNVTPCPEPEAGRAERDQDENTEMNEHRMERVQTFIADNRSLINDLEESIRCQQQLQREQQSLDAEKSMRAFDQIWNKRLAKNPEDCQQTNKEKEQTREKMPRERPTPQGDRKNAAPPQESGKIRRTQEGDRQQQTNGAVQQKREQKTVKQGSGADKSTNRFAPEKSKALSTSEESSARNMERYAQLTENCTQRIAELTELITKVREEKQRLVEVTLTSNSDGERQSTEYLELPTGQQQTRCRTISDRSDSQTPSTSEALPLQKHKPTAASRDSGIADSRPITAQGQVCIDVEPISLGSSTQNNTARGRVRAPPATIRRYSPQLNAEDLAHELSTITEVETPGQSHIVAATPVPKPFPSFDQYAKELHLDLSRLDADQSQRLQGEFNDLILAIRQRNQGTDYREFPSINAYLHNMTSTRIHVEIGQDADQATLSPGELMRQLRVITHSIQDFPKRREYFEKLMAKQPPDQRDLIDSASLENDSTDSFNVEEELRQRKILKNSFRRGNATETTLTAQEVASSTRRESVAPVTNDQPNESGIDPLSGSNFSSDADQRSPCWHATMHERQQQVDELCSSTTASSPERRPRKSRLRGGHEHNNRSKDDSTVQDASQIGRSLNLREFLTRELLKHRVHDDVASESSDESLRGHFLKSVLHSLSPSNNTQTPGVGVSHATGATNDRQKTSTPVGSFLSIPEKAGSMSNTGSQLFSGESRISLVNYPDGTPPIPFEQQSKLSTNQTRQSSGQIGSGVRTTHRKSPRK
Protein: Cytochrome c-type biogenesis protein CcmF (P33927)
Organism: Escherichia coli (strain K12)
Function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Thiol:disulfide interchange protein DsbE
- Cytochrome c-type biogenesis protein CcmE
- Cytochrome c-type biogenesis protein CcmH
- Heme exporter protein C
- Heme exporter protein B
- Cytochrome c biogenesis ATP-binding export protein CcmA
- Heme exporter protein D
- Formate-dependent nitrite reductase complex subunit NrfF
- Formate-dependent nitrite reductase complex subunit NrfG
- Cytochrome c-type protein NapC
Sequence:
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVSPQKTAPEAV
Protein: CAP-GLY domain-containing linker protein 1a (CAP-Gly domain-containing linker protein 1 isoform X1) (E7F2X0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Serine/threonine-protein kinase TOR
- NudC nuclear distribution protein.
- Dynactin subunit 2
- Serine/threonine-protein kinase PLK
- Cell division cycle 20 homolog
- Mitochondrial ribosomal protein S27.
- Dynactin 1b.
Sequence:
MSTSKPSGLKAPSKIGRPANTGPTKTSPSAGASKAAQSDKSSAEAPDAGEQFKVGDRVWVNGNKPGVVQFLGETQFAPGQWAGIVLDEPIGKNDGSVSGVRYFQCEALRGIFTRPSKLSSTEGEADGTTTAPPSRAASPTPSTTSVSASSKKPASPTKAAAPTSDLVRSKSESVSNLSESGSVKKGERELKINDRVLVAGSKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVTRIGFPSTTPAKAKTTVRKTTATTAATPSALKRSPSASSISSMSSVASSASCKPSRTGLLTETSTRYSRKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATNHVGEVEQELTLLREGQEQYASEVNDKMDQLRALVEAADREKVELLNQLEEEKRKVEDLQFRVEEACITKGDLETQTQLEHALLKELEQSLLFEKTKAEKLQRELEDSRVATVSEKSRILELERDLSMKDKESAALRKSLEALSSQDGVCDSAVAALQEQLSLIRSQQAEQSHSHQAELSSMREKLEAQEKAHREALMHLQASSSRLSKDNEQLLAELAKSKEENSNVVEQWSDKLKSVEASHQQALEELKTSREASKAELSDALERLKSTHKLELEELAKKHSSEAAGWVGEGMEHKAQLLKVAEENERQVEMLRSSLEKAEEQHLVELEDAMGKLHAAELRVKELEDSGVKISEQLKEKVQEALEQSEALQSLQTQHSQGNQEMQRLLSQVEEAKSKARSQEEKVTELNSVLEVKQQELSGLLQEKSSLEQEVSLLKQNLEKTTNDQAKSSQTNQELQEELRNKEDKCTSLSAELQDTKSQLAGLQRSLKASEERCLLLTKDKTKLENDIMDMTKSSGDSSTLITKLNEENKRKEGRLEELQKQLEEEREKTAQTEEKLSHTRVQTENEAKSLMQKHQAELANLQEKIKLLEKSIEDNHAKAKDLHASGEKALTDAAELHSKEKQELQSKYEKVQQELSASQNESLELRKQIEELMTFKEKTAVLEKAEEAARASLEKMTQDNLQLQKDKSDSEAQVTALRNTVQEMQSKLDALKQQNTQYEESLSSDGQRISSLSKEIEDLKQAVAEKSQAVDDLKNEKEKLVVDLANSHKDSNIILNLKKECDRLNEQLKEAKTRESSFRSESEKEKAALQQTLQTQSGLVSEKDKELNSLRNELDALKQQNSQYQESLSSDSERINSLSKEIEELKQAAVEKSQAVDDLKNEKEKLTMDLANSLKDSNILLNLKKECDNLNDQLKELKKRESTLTSESEKEKAALQQSLQTQSALISEKDKELDSVRNELKKERDSLNSQLKKMEMRESTLTKETEKEKAALQQSLQTQSALISEKDKELDSMRNEMGGLRDQTQTLQSSLKSQKSENIQLQERLKGLERSLADAQIPSKGDNASDDSALRMWKEAKENAEHQVEFLNSVIVELQRKNEDLKSKLEKMAEAALNGNGAAEMDSRNNSHTEPAIKKKPPPRLFCDICDCFDLHDTEDCPTQDQMEDSPPHTTYHGSPNDERPYCDICEVFGHWTDSCNDDQTF
Protein: Mitogen-activated protein kinase kinase kinase kinase (EC 2.7.11.1) (Q7KV89)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQNNFKPSLPPRRPEDHLDVLAAQLSELGVVFSQQPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPDDDDQAGDRTLIMKRNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW
Protein: Histone H2B type 1-M (Histone H2B.e) (H2B/e) (Q99879)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H4
- Histone H2A type 1-C
- Histone H3.2
- Histone H3-like centromeric protein A
- Histone H2A type 1-D
- Histone H2B type 1-B
- Histone H2A type 2-B
- Histone H2B type 1-O
- Centromere protein N
- Histone H2A.J
Sequence:
MPEPVKSAPVPKKGSKKAINKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
Protein: Nucleoporin (Q38A83)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNSNSLLGELAKECAPLLLAPRADDPDAVVRRLRILPADGIYRCSSRDSIITPYVFSGDAEHSAPPNHSLTPEQSGSVVTSDILGISTEVCPLQTALSLASVECVAANQKHLFELNVFLQLLRQAPASYTSSLFWSVLIRRLGELGFYEIMKGNINTLWARIGRQLLRSGEMFNALRLLQTSCDVVLHYSEHAVQYPPDATLLGEFAVLARQMWAESSSPVVRRCALVVSAFLTKFADLVPLDLLSDASETKRDAPHLLAVVAKAPTLFKEEEETAAAGENLRVVLTVAFTTTAYSIPTTMYFRGEGPQSASLSLVQHRFASALHQLLVLASYGFWDHFSAESLLSLTEASAVYSRLWNSFPPKMFTLWGRICQNNLVTSCKMYTSSLFNYCISAAAYHYSLGELEGITRRYAVGDVSHGGEPSSTEPLQAADEGQKRGRQQEQHEDVSERILGSGADACEKLDITPHLRETFRLMVTGWGSFQPGDRNFLRSGLVVLHVLLLNYPYQLEELGKAIGFDVGQLLHGIVMGLLASDVDSAQIMETVYSIIFRFYEMFDIFDVVSNLLPPQVMADVGLKCETTEKALMQAQLYGALLETHGEDISPLPLLEAATHISRGAILRFSSATSFFVKWFTVTERSLLLQPRDALVDLFSLKGAGDKLVQCLCEGALALVRELQSGNVIIDGFPVAPVLESVISCISSAVLYGGQQNALVACAIAVHGEGDVPASLMLFCLVFAANANITLLESSARLLAYVVEHSDEGLFTTLRLHTSIEMKKRLLAGLHQQLGSAASADSTGARMVRLATLHHLLRFDPAAFYYLMAAEDHGKESAELRITPFLRDVVKSSDTTALEKSEALACLKALDDVGVSTTEVATLLSNMRVDSPITGGVLTAAAVYYACGVYFHKYKLDGGESSVAPTGKGVTQRLRLSDSFTVNMMQGKVLIGPSDEACKMLKFSCEALKQCISFYEQTAKHLRYGDANNATVLPSIDSYPAAHSPLVLSVAGTAGRSAGCTDRRCRSLVDPRQMCNGQATFSSCLLAAEGISMWEGVANVDLDRLASALVAITRLTTSIEAALWILYGEKEVDSVTAQLLEAALCAVQMLGSPVPQLRDQVSACLDGALTLAQTAAVILTRMPSDGNSLLRTGEFIGLFSVFVKTLSLYRDDDDVISRGLKIVGVFKPVEVADEEVVIHIFDTIASVVERHASSSPTDFLVPIVAQVTVIFTSIGEFCPTKCALGIVNNLWSCAMNVSQMIVIADPCSPLSNKFDVIVEAVRAILLQCDGILGYLSYDRIMPMATALGQLSNASCYDALDHLYKPQAWHGAWLSLLRLFHAVLIGCGGGSENTLGWLSIISSWATTSPRFREAVSGFTYCRGGVSRSSGPHSWEWQEMHIATLIISLLSSLGTSTAPLTPHVQRCFCRIRHFTCQTTGTPCAASLNELFLATVRHQLSYLIFHSPPSGYMEGEPPIVTISRYRYPSNGEASTSDGLLLQKAAKVNEGDQKEEQLSFYTLRCFIFRELSILRKSCRDDSSATGALTSPDNTPVMRSSSLNTSTDGFSDIDVRDGGLQVVAPHLLNVQLALILFVRNGHFQVFQRCLDLWEQQELVEGLDELHRFLNLLSHYARRLESTKLISVVETVQEELQGLAERLRSGATSWRTTGATL
Protein: Calcium channel, voltage-dependent, beta 4b subunit (Voltage-dependent L-type calcium channel subunit beta-4b isoform 1) (Voltage-gated calcium channel beta-4 subunit variant 1) (B0F0C6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MYDNLYLHGFEDSEAGSADSYTSRPSDSDVSLEEERPEGGSQGRQEREQQAQLQLERAKAKAVAFAVKTNVSYCGALDEDVPVPGTAISFDAKDFLHIKEKFNNDWWIGRLVKEGCEIGFIPSPLKLENIRAQLEQKKSRVQGKSSGSSSSSLGDVMSSGKQKQKVTEHVAPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRITITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLMKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHTSSSTPLNPLLGRNLGPAALAPYTTSAISGLQNQQGQKTRHANHTGDHSTPNERRNLMTSDENYHNERAHKGRNRGSSGSQHGGSGRDHHYMEEQQGYQDPYQDTYKPHRNRSSPGSYSQDSRHRL
Protein: GH11591p (P53, isoform A) (P53, isoform C) (Transcription factor) (p53 tumor suppressor-like protein) (p53-like regulator of apoptosis and cell cycle) (Q9N6D8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MYISQPMSWHKESTDSEDDSTEVDIKEDIPKTVEVSGSELTTEPMAFLQGLNSGNLMQFSQQSVLREMMLQDIQIQANTLPKLENHNIGGYCFSMVLDEPPKSLWMYSIPLNKLYIRMNKAFNVDVQFKSKMPIQPLNLRVFLCFSNDVSAPVVRCQNHLSVEPLTANNAKMRESLLRSENPNSVYCGNAQGKGISERFSVVVPLNMSRSVTRSGLTRQTLAFKFVCQNSCIGRKETSLVFCLEKACGDIVGQHVIHVKICTCPKRDRIQDERQLNSKKRKSVPEAAEEDEPSKVRRCIAIKTEDTESNDSRDCDDSAAEWNVSRTPDGDYRLAITCPNKEWLLQSIEGMIKEAAAEVLRNPNQENLRRHANKLLSLKKRAYELP
Protein: Transcription factor bHLH27 (Basic helix-loop-helix protein 27) (AtbHLH27) (bHLH 27) (Transcription factor EN 42) (bHLH transcription factor bHLH027) (Q700E3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Patched family protein
- Patched family protein
- Importin subunit beta-1
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- Transcription factor bHLH139
- Transcription factor bHLH51
Sequence:
MEDLDHEYKNYWETTMFFQNQELEFDSWPMEEAFSGSGESSSPDGAATSPASSKNVVSERNRRQKLNQRLFALRSVVPNISKLDKASVIKDSIDYMQELIDQEKTLEAEIRELESRSTLLENPVRDYDCNFAETHLQDFSDNNDMRSKKFKQMDYSTRVQHYPIEVLEMKVTWMGEKTVVVCITCSKKRETMVQLCKVLESLNLNILTTNFSSFTSRLSTTLFLQVTLSLSPSLISLFGNVITSTNYKILNASREYCTCLVLV
Protein: Adrenodoxin, putative (Q584K7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Adrenodoxin reductase, putative
- Iron-sulfur cluster assembly protein, putative
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Nitrate reductase, putative
- FAD/NAD
- NADH-ubiquinone oxidoreductase, mitochondrial, putative
- NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial
- Iron-containing hydrogenase, putative
- Lanosterol 14-alpha-demethylase
- Cytochrome P450, putative
Sequence:
MLSATFGTLGTSCGRGFLQRQGLLTTFMGRFCHSGGGGNNQNNDSSNSGNDGSSTPGAIRVNVTTAEGEKITFSAPSGLTLMEALRDVARVDIEAACDGTCACSTCHVILREEDFGKLTAASEDEMDMLDLAPQVTPTSRLACQVKLSKELDGITLQMPSETTNEMR
Protein: Cyanate hydratase (Cyanase) (EC 4.2.1.104) (Cyanate hydrolase) (Cyanate lyase) (O22683)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
Interaction partners:
- Signal peptidase complex subunit 1
- Signal peptidase complex subunit 1
- Signal peptidase complex catalytic subunit SEC11
- signal peptidase I
- Signal peptidase complex subunit 3A
- Signal peptidase complex subunit 3B
- Probable galacturonosyltransferase 7
- Beta carbonic anhydrase 6, mitochondrial
- Beta carbonic anhydrase 3
- Beta carbonic anhydrase 1, chloroplastic
Sequence:
MEAAKKQSVTNQLLAVKSASGKTFSQLAAETGLTNVYVAQLLRRQAQLKPDTVPKLKEALPALTDELIGDMMSPPWRSYDPNLIQEPTIYRLNEAVMHFGESIKEIINEDFGDGIMSAIDFYCSVDKIKGVDGNNRVVVTLDGKYLSHSEQRTENMVSRLNLKGGTSE
Protein: Mitochondrial proton/calcium exchanger protein (Electroneutral mitochondrial K(+)/H(+)exchanger) (KHE) (Leucine zipper-EF-hand-containing transmembrane protein 1) (O95202)
Organism: Homo sapiens (Human)
Function: Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization. In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:14706454, ECO:0000269|PubMed:15138253, ECO:0000269|PubMed:18628306, ECO:0000269|PubMed:19797662, ECO:0000269|PubMed:32139798}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Trafficking protein particle complex subunit 10
- Mitochondrial sodium/calcium exchanger protein
- Histone-lysine N-methyltransferase NSD2
- Calcium uptake protein 1, mitochondrial
- Calcium uniporter protein, mitochondrial
- Calcium uptake protein 2, mitochondrial
- MICOS complex subunit MIC60
- Mitochondrial calcium uniporter regulator 1
Sequence:
MASILLRSCRGRAPARLPPPPRYTVPRGSPGDPAHLSCASTLGLRNCLNVPFGCCTPIHPVYTSSRGDHLGCWALRPECLRIVSRAPWTSTSVGFVAVGPQCLPVRGWHSSRPVRDDSVVEKSLKSLKDKNKKLEEGGPVYSPPAEVVVKKSLGQRVLDELKHYYHGFRLLWIDTKIAARMLWRILNGHSLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTFETQSLKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGSATKDFSVFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRSEVAKDFEPERVVAAPQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVKHIPESKLTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEEKVEEKEKAKEKAEKEVAEVKS
Protein: Cleavage stimulation factor subunit 77 (AtCstF-77) (AtCstF77) (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (Protein SUPPRESSORS OF OVEREXPRESSED FCA 2) (SOF2) (Q8GUP1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: One of the multiple factors required for polyadenylation and 3'-end cleavage of pre-mRNAs (By similarity). Required for the targeted 3' processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q12996}.
Interaction partners:
- Cleavage stimulation factor subunit 50
- FIP1[V]-like protein
- Cleavage stimulating factor 64
- Polyadenylation and cleavage factor homolog 5
- 30-kDa cleavage and polyadenylation specificity factor 30
- Polyadenylation and cleavage factor homolog 1
- HEAT repeat-containing protein
- Cleavage and polyadenylation specificity factor subunit 2
- Symplekin
- Flowering time control protein FY
Sequence:
MADKYIVEEAEALAKRALHSPIAQATPIYEQLLSLYPTSARFWKQYVEAQMAVNNDDATKQIFSRCLLTCLQVPLWQCYIRFIRKVYDKKGAEGQEETTKAFEFMLNYIGTDIASGPIWTEYIAFLKSLPALNLNEDLHRKTALRKVYHRAILTPTHHVEQLWKDYENFENTVNRQLAKGLVNEYQPKFNSARAVYRERKKYIEEIDWNMLAVPPTGTSKEETQWVAWKKFLSFEKGNPQRIDTASSTKRIIYAYEQCLMCLYHYPDVWYDYAEWHVKSGSTDAAIKVFQRALKAIPDSEMLKYAFAEMEESRGAIQSAKKLYENILGASTNSLAHIQYLRFLRRAEGVEAARKYFLDARKSPSCTYHVYIAFATMAFCIDKEPKVAHNIFEEGLKLYMSEPVYILKYADFLTRLNDDRNIRALFERALSTLPVEDSAEVWKRFIQFEQTYGDLASILKVEQRMKEALSGKGEEGSSPPESSLQDVVSRYSYMDLWPCTSNDLDHLARQELLVKNLNKKAGKTNLPHVPAAIGSVASSSKVVYPDTSQMVVQDPTKKSEFASSANPVAASASNTFPSTVTATATHGSASTFDEIPKTTPPALVAFLANLPIVDGPTPNVDVVLSICLQSDFPTGQTVKQSFAAKGNPPSQNDPSGPTRGVSQRLPRDRRATKRKDSDRQEEDDTATVQSQPLPTDVFRLRQMRKARGIATSSQTPTGSTSYGSAFSGELSGSTG
Protein: Serine incorporator 5 (Q86VE9)
Organism: Homo sapiens (Human)
Function: Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm. Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:26416733, ECO:0000269|PubMed:26416734}; Multi-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000269|PubMed:26416734, ECO:0000305|PubMed:26416733}. Note=(Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (PubMed:26416733, PubMed:26416734). Localizes to the cell membrane, where it is efficiently incorporated into budding virions and impairs subsequent virion entry into target cells (PubMed:26416733, PubMed:26416734). {ECO:0000269|PubMed:26416734, ECO:0000305|PubMed:26416733}.
Interaction partners:
- Major facilitator superfamily domain-containing protein 10
Sequence:
MSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHIPFFEDMCKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEFAHKWNKNWTAGTASNKLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGVISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPDFGQDLYRDENLVTILGTSLLIGCILYSCLTSTTRSSSDALQGRYAAPELEIARCCFCFSPGGEDTEEQQPGKEGPRVIYDEKKGTVYIYSYFHFVFFLASLYVMMTVTNWFNHVRSAFHLLP
Protein: Os08g0477900 protein (Q6ZJC8)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- Transcription factor RF2a
- Os03g0830500 protein
- Os03g0101800 protein
- Os03g0830400 protein
- Os04g0461600 protein
- Os01g0267400 protein
- Defective in exine formation protein, putative, expressed
- Os10g0112100 protein
- Os03g0830300 protein
- Os03g0829900 protein
Sequence:
MVTDGECSAAAVRKGGSPAVRSHSEAERKRRQRINAHLATLRTLVPSASRMDKAALLGEVVRHVRELRCRADDATEGADVVVPGEGDEVGVEDEDDDEGERDEGCYVVGGGDRRWRRRVRAWVCCADRPGLMSDLGRAVRSVSARPVRAEVATVGGRTRSVLELDVVVASDAADNDRAVALSALRAALRTVLLNREELLAAAAAAATDGYKRPRFSPRCSSLT