wanglab/gogpt-training-data huggingface dataset:
Protein: Phospholipase A1-Ibeta2, chloroplastic (EC 3.1.1.-) (O23522)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acylhydrolase that catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position. Has a strong galactolipase activity toward digalactosyldiacylglycerol (DGDG). Hydrolyzes triacylglycerol (TAG), but has a low activity toward phosphatidylcholine (PC) and monogalactosyldiacylglycerol (MGDG).
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Transmembrane protein
- Lipase class 3 family protein
- Phospholipase A1 PLIP2, chloroplastic
- RGG repeats nuclear RNA binding protein A
- Serine/Threonine-kinase RLCKVII protein
Sequence:
MQTLTPNADIFHAKRRRFTCNTHTSTLIPTKPLSVSPARKTNKEHLRNLENVLRTSSNSIDHIENVTSRQEKTTKNTSTSSLLGGLNLARIWPQMKAAVDEMSPKNLKRLQRLLSKSSEERSPKSKLGSKWRELHGLNNWAGLLDPLDENLRRELVRYGEFVQAAYHAFHSDPEGSPRHVALPDGSFKVTKSLYATSSVRLPKWIDDVAPDLRWMTKQTSWVGYVAVCDDPREIRRMGRREIVIALRGTATLLEWSENFRPNLVSMPEPKPDQSDPTRPKVECGFNSLYTTGDQHAPSLAESLVGEISRLVELYAGEELSISVTGHSLGAAIALLAADDIAERVPHAPPVAVFSFGGPRVGNREFADRLDSKGVKVLRVVNSQDVVTKVPGIFADNDKQGQSRNNGRSPGGIMEMVERNNPWAYSHVGAELRVDMKMSPYLKPNADVACCHDLEAYLHLVDGFLASNCPFRANAKRSLRKLLDEQRSNVKVLYTGKSLRLNRTFHDNGDVLPSPSSS
Protein: Cyclotide hyen-E (C0HLN9)
Organism: Pigea enneasperma (Spade flower) (Afrohybanthus enneaspermus)
Function: Probably participates in a plant defense mechanism (By similarity). Has cytotoxic activity against HUVEC cells (LC(50)= 2.17 uM) and various cancer cells including HeLa (LC(50)= 3.05 uM), MCF-7 and K562. Displays very weak hemolytic activity. Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE).
Interaction partners:
Sequence:
GVPCGESCVYIPCFTGIINCSCRDKVCYNN
Protein: Protein RER1A (AtRER1A) (O48670)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein RETICULATA-RELATED 1
- Protein transport protein SEC24 C
- Protein transport protein SEC23 A
- Vacuolar-sorting receptor 3
- SIT4 phosphatase-associated family protein
- SIT4 phosphatase-associated family protein
- At1g07990/T6D22_5
- Vacuolar protein sorting-associated protein 45 homolog
- SIT4 phosphatase-associated family protein
- 2-Cys peroxiredoxin BAS1-like, chloroplastic
Sequence:
MDESGGDSGSVATPVQQRAHEAWRIYQHYLDKTTPHANYRWIGTLVVALIYCLRVYYIQGFYIIAYGLGIYLLNLLIGFLSPLVDPEAGGVSDGPSLPTRGSDEFKPFIRRLPEFKFWYSMTKAFCIAFLMTFFSVFDVPVFWPILLCYWIVLFVLTMRRQIAHMIKYKYIPFSFGKQKYGGRSSSGSRAD
Protein: EG:BACH7M4.1 protein (Q7K6U7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNFASRVYLSKTTAICAAYKKYCNGIKRADCVLVNKSRQTGSEFIAFITEPAVPRKRPDLTMFIHRPLQHFREILKLMQLLAGNCHVDTEEHKNFSTVINELQAAYREITVSSGLMEPLGEGRPLLTLQDLESRMVFTKCKPFTLAVQGRQWIFGGDLSRVEGRSVKPYWTLLFSDIIVFAKVSRDRVLFITEEPIPIANVVDSCFHMRKKTTEFRLTVDPNGRLAESPTGYCAPDLTRTPKRGARRKSLILRAPSLELKAVWQNLLQRQIFLVNAALGSTPLSSPLDSPDVLNTLVPLSDIGLTTASMGSMKLPSLDSIHLKQQQKQQVRLFRSKRLDSGDSYENLQRLASAVRHHCASTTTSSATQTQSHPQPPLCTTSLPSRTNSPARNQRHPNGQGHVGGSVPNGVGGVSFGGCNTNSSCLSSSASLTQTQTQVHTQTLNHSQTHSQTQTSVLSLSSCKCLTVIPEVTSEPPVNQHASQKLLEFSLSSVGRSFIDESGGVVGGQVSLTTPETPTPNISPTTSQPCNSDAFSNDFVATSTTGKGPNIPLAEFGGSWDLLELDLQLHEVNLDPSYDTDVEECIFLGDEEDREGTEGHGHDEDSDEDDSVVVDDPFGMLPTRPTPPDSLDL
Protein: Uncharacterized protein C21.03c (O94645)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MTEDAEKRRYWLMKAEGEPRYVKGINVAFTFEMLEEITEDGKMESWSGVRNYEARNMIRDEIKIGDYAFLYCSNCKFPHIKGVMRICSNSHPDDSAWNSNDPYYDPKSTPQNPRWYSVGVQSEYKLDRPVTLRELKMHKENQLKSMELLNRSRLSISRVKPEEWKFIHELSKQPEPEEIIKARLQEEEKVAKRKRKLNLSDGENKAKSPYSSISENDASLDIIKRSRIKDVRSQKDNAL
Protein: TRIO/F-actin-binding protein (F4IPZ8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At3g09000
- Protein SPIRAL1
- Glucose-6-phosphate/phosphate translocator 1, chloroplastic
- GPI-anchored protein
- At2g40070
- Glucose-6-phosphate/phosphate translocator 2, chloroplastic
Sequence:
MGEEKENWRSELDDINGLSLIDFSAEDDNLLLSSFLDPTTFDFSDTDKEDRGLCLFGDTHNCCDEETLGSTTLEEKEPHKIMKTNLRKSLAWDKAFFTNAGVLEPDELSSMMGRKSLPAVQEDLHRSTESMSTLKSDCTVETGQEFFMCDAATPDKRKDLGSTEAVPSPTTSTLDDPSSEEKMKPNPIRKRPGIRSQGLAKATKHPVASEEHNTSISRPSTGLNRPSSGLSKTKRASVDTNKAKQETNPKSSGGKEPLASRVPISRRPRPIVSTPVVPFKSALRSSVASKNELTSSCSSIESCLSVSSTASNKPSIHSVKQKKDQSLRIASHSLANRPKSSAGSRNIDQLKVPPVSAGRTYKFNVSRLSSSVDWSSESPRAFTPNKMAKGNKKSVHGDNGPPTDYTTQTLKPLNNSKDVSVVQDDPKPSASMMKPTGLRVPSPKVGYFDGARGSVARTPTGSCTGPVSGLSKHGACSPDEFTPSRTAKSQPTMSKAAVRPVSRSSRLIVSASPKLTNKRYSKVSAEEQLG
Protein: Non-specific lethal 1, isoform M (E2QD16)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- KAT8 regulatory NSL complex subunit 2
- Reduction in Cnn dots 1, isoform E
- Protein will die slowly
- Histone acetyltransferase MOF
- Protein MBD-R2
- GH01794p
- Protein male-specific lethal-3
- Histone acetyltransferase Tip60
- Helicase domino
- Enhancer of polycomb-like protein
Sequence:
MAPALTAEPLSPKEKLTSTASPSARSSSESGGVGCAVGLVKKPATPTPATATTRITRSSAAAASVTASPHLQQQRSSLAINNKRKSGNAKASNEPMGLSTAPTPHSTTSPNPSTDTAAASTSAVEHNNNDSNSTSAGNSTSADNSSTPKDNSTAQLLADLTINFEETISAEICLRKTLPDVSLGKEPVPPASVLAVATSSTSAGSALSLSAVDEVTKIEIDNIEERLSQLDGNATGRPEEHVAPPSVPVPVQEAPNTPTRPQAPPSAHLESPQPARTQQQSIQQMTPQSTTSSNNFLKDGAAGAVLEDQDIEEVLKALKTFDGGHVNPDTICEFFDEVWEEAAPAAPLPPAPPENVVDVPGAKPSCSGILVSGSNISQPNVIIKQEQRPWQESHAELEQQQHVISRRIEFLLRRMRKLQARAMCRHASEEVVGIMEWSARSSHKAPVPARSSTLTEQEATVLSIVSGRPSSTFWEEQNKHPLPASQMSNVIRHIATAAKHQQICHSASGSSATLAPSSSWYNSCNSSALPMKRPRKNQLDASVATGATPTAPAPGAVTSRQAAGTTGSATGSNTPRADDIVPGYDTYVTNELTHVSGLLHTELREVQNAIDSDATESSSGGESADEMVTYNNNQQLSLPITRRAVWRYSRDRAAIALRWSWLCSQLTDLEMKIRQHSDLYMDLTQSKGEIQLESTAKTSPSLAQPANGIKEEPGSDYLCSRARPLVLSEFRKRKLFQTTNMHTISKKAARPSNIKCGCQWPQVPCTLCTGRTDPTAPRDLVETMMPQNRVALLDAGYHPVLSFASDVSQSVHLEAVARQPDWQYRVMRSQPKAIVKAMWKAERETIASGGVGGQGGSRRSGDAAKRRYIRRKERNNNSNKEAGSGAKAAAVAAGGAGGNGSSSVGGGDSGNGTGTATTSSSTTPTTTPLVANTAARGKRQPQHPTGANSSSSLWPDSRQRQRQRHHSPSSTSISALSGAKKARKSATNSSSSNSTQQQQNHHGTKINNHHLNGYGDQWGEQSRSRRNSSPSNSHKNERTSERRVRPIYDINNIVIPYSMLAQSKMEIIPYKEIPIPKWRIVDSDNDKGKHSSDESMERKLSNGCVASKSEELAKQQLPPPPDQDQEQPALQPPKVNGLKENQAVKHNNNNNTNNNNNKNGLVNGNAKKDELKAAEDHDTQSKEDDDPKEKVVKPKLNGNLIKNPIDKTAETQDKIAQPAPEPPLPKRPKLETPTSNEVTKANGQLVQQQLESRESEEEPQHVDEDLSDEAFIMRHQRALLEERRRFETFLKFPWSTRSRANRRVDSRAESSGANTPDPASPAPHLGGPGHDNESIPSPLAYPLDAFNESGELLTGGQARQARRRTTSSKLKDQLERRSTTPDLRESYTVMPSPFEPLNFPLSDEVYQRLLAETYAPPRSMTVSKRAKSKSISSNCDGGNTFTGGSGSRRSSKCKIKPNGQLNGQLNGHPAAAKLNGIDAANEGGISEPEEEEMLLEDEDDDYPKHHLAPLDDEEPSTPDVEHELYDSAIDAYLADPEALEEDMGEDPFEDDDPNDPEWKTRTEGVRSRRI
Protein: Ribosome production factor 2 homolog (Brix domain-containing protein 1 homolog) (Ribosome biogenesis protein RPF2 homolog) (Q9LUG5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- Pescadillo homolog
- Pumilio homolog 24
- AT5g04600/T32M21_200
- Ribosome biogenesis regulatory protein homolog
- Nuclear/nucleolar GTPase 2
- Probable rRNA-processing protein EBP2 homolog
- Ribosome assembly factor mrt4
- Probable ribosome biogenesis protein RLP24
- Ribosome biogenesis protein BOP1 homolog
- Ribosome biogenesis protein WDR12 homolog
Sequence:
MMEIRTPKTGKAKRVLESRAPKLVETGKKTLILHGTKTSATLSSVMTELYRLKKGGAIRYSRRNENIRPFESGGETSLEFFSQKTDCSIFVYGSHTKKRPDNLVLGRMYDHQVYDLIEVGIENFKSLRAFSYDKKFAPHEGTKPFICFIGEGFENVSELKHLKEVLTDLFRGEVVDNLNLTGLDRAYVCSAISPTKVFLTHCALKLKKSGSIVPRMELVEVGPSMDLVIRRNRLPNDSLMKEAMRTSKDKPKKKEKNVDQDAVLGKTGKIYMPDQKLKEMKLFDKSKGSKRERKDAKLKHKEETVAKKMKVSSE
Protein: NADP-reducing hydrogenase subunit HndC (EC 1.12.1.3) (Hydrogen dehydrogenase (NADP(+))) (Q46507)
Organism: Solidesulfovibrio fructosivorans (Desulfovibrio fructosivorans)
Function: Catalyzes the reduction of NADP in the presence of molecular H2 to yield NADPH.
Interaction partners:
Sequence:
MAATTTEKKQLRIATRNCGFIDPESIDDYIALRGYEGLAKVLTMTPAEVVDLVKRSGLRGRGGAGFPTGIKWGIALGNKADQKYMVCNADEGDPEFMDRAVLEGDPHSVVEAMAIGGYAIGATRGTVYIRAEYPLAIKRLKKAIDDAREYGLLGENIFGSGFDFDIELKYGAGAFVCGEETALIRSMEGKRGEPVTKPPFPAQSGYWEKPTIVNNVETFANIPAIIINGADWFSGIGTATSKGTKVFALAGKIQNVGLIEVPMGISLREVIFDIGGGCPDGKAFKAVQTGGPSGGALANKDLDVAIDYESLAACKSIMGSGGMVVMDEDDCMVSVAKFFLDFTMDETCGKCTPCRIGSKRLYEILDRITKGKGTRADLDRLKSLSEIIKDTALCGLGQTMPNPILSTMDTFANEYEAHVDDKKCPAHVCTALLTYTIDPAKCTGCGLCTRVCPVECISGTKKQPHTIDTTRCIKCGACYDKCKFDSIIKQ
Protein: Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) (P55859)
Organism: Bos taurus (Bovine)
Function: Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity). Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P00491}.
Interaction partners:
- Adenine phosphoribosyltransferase
- Xanthine dehydrogenase/oxidase
- Adenosine deaminase
- Guanine deaminase
- Uridine phosphorylase
- 5'-nucleotidase
- Adenosine deaminase 2
- Adenosine kinase
- Uridine phosphorylase
- 5', 3'-nucleotidase
Sequence:
MANGYTYEDYQDTAKWLLSHTEQRPQVAVICGSGLGGLVNKLTQAQTFDYSEIPNFPESTVPGHAGRLVFGILNGRACVMMQGRFHMYEGYPFWKVTFPVRVFRLLGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFSGENPLRGPNEERFGVRFPAMSDAYDRDMRQKAHSTWKQMGEQRELQEGTYVMLGGPNFETVAECRLLRNLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESQGKANHEEVLEAGKQAAQKLEQFVSLLMASIPVSGHTG
Protein: Uncharacterized transcriptional regulatory protein C3H8.08c (Q10144)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MSSSPPALKKFRKRSPKSCLICRRRKVKCDRQQPCSRCKERNEVCTYADDTIDKMNVGPHPSHSENASDSETTLEVSPDINPKKNEKFDFYGWRSLFELIKYRKDSDMCSSRPSFSIQAYSSYKDNVVVESLANLLPPFCISQKIVNLFFKTLNVVCPIYDQETVEKSLNNIESPESFSYEDAFTLLPIIAATIQLSDLPDVILNFYNSAGITPLESSRLINLKLNEISEQEYKHLCLPDKEIIQMLLLRAYATKFRTRIRGVNTDLCRSIHVSTLVTPLFQVTEKIGKNTSDLWFALCEIDGLECVLKYRPPFIQHDTYGRLKPLRCFFNDDISYNFHLLLGRLLDCGVSIYKSVHSLTVSKFIDKLESYESQLSLILVDIEAKFYDPSNEDIQFRYIFLKMVFWTARVNLYQCFITLDSGILEDEETIIGNLGESCIQCVRLLISQITILEKRGWLLVALLEIIHALMLAAFCRDKGFEVPSDLGDITLYVQERMVDIVTFDDGMAVRFGYVLRFINSMLHPNEPPMQDAEPETTEDPSKLFADIFDFTSNYFIPSALLDQ
Protein: MIR domain-containing protein (O61793)
Organism: Caenorhabditis elegans
Interaction partners:
- DnaJ homolog dnj-20
- Calreticulin
Sequence:
MPKLPLLLSFPLLFFASFAYADEDFVTCYSVLKFINANDGSRLHSHDVKYGSGSGQQSVTAVKNSDDINSHWQIFPALNAKCNRGDAIKCGDKIRLKHLTTGTFLHSHHFTAPLSKQHQEVSAFGSEAESDTGDDWTVICNGDEWLESEQFKLRHAVTGSYLSLSGQQFGRPIHGQREVVGTDSITGGSAWKVAEGIYIKHQQKDL
Protein: Phosphoglycerate kinase 2, chloroplastic (EC 2.7.2.3) (P50318)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Triosephosphate isomerase, cytosolic
- Triosephosphate isomerase, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic
- Glyceraldehyde-3-phosphate dehydrogenase GAPCP1, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPCP2, chloroplastic
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1
- Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2
- Glyceraldehyde-3-phosphate dehydrogenase GAPB, chloroplastic
- Glyceraldehyde-3-phosphate dehydrogenase GAPA2, chloroplastic
Sequence:
MASTAATAALSIIKSTGGAAVTRSSRASFGHIPSTSVSARRLGFSAVVDSRFSVHVASKVHSVRGKGARGVITMAKKSVGDLNSVDLKGKKVFVRADLNVPLDDNQNITDDTRIRAAIPTIKFLIENGAKVILSTHLGRPKGVTPKFSLAPLVPRLSELLGIEVVKADDCIGPEVETLVASLPEGGVLLLENVRFYKEEEKNEPDFAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSNPKRPFAAIVGGSKVSSKIGVIESLLEKCDILLLGGGMIFTFYKAQGLSVGSSLVEEDKLELATTLLAKAKARGVSLLLPTDVVIADKFAPDANSKIVPASAIPDGWMGLDIGPDSVKTFNEALDTTQTVIWNGPMGVFEFEKFAKGTEAVANKLAELSKKGVTTIIGGGDSVAAVEKVGVAGVMSHISTGGGASLELLEGKVLPGVVALDEATPVTV
Protein: Proteasome subunit beta (Q9PUS3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU004203}. Nucleus {ECO:0000256|RuleBase:RU004203}.
Interaction partners:
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta type-1
- Proteasome subunit alpha type
- Proteasome subunit beta
Sequence:
MSEELFPEPGWLSEEVKTGTTIIAVTFDGGVVIGSDSRVSAGESVVNRVMNKLSPLHDKIYCALSGSAADAQTIAEIVNYQLDVHSIEVEDDPLVCSAATLVKNISYKYKEELSAHLIVAGWDKKGGGQVYATLSGLLTKQPFAIGGSGSFYINGFVDAEYKKNMTKRECQEFVVNALTLAMGRDGSSGGVAYVVTIDKDGTEEKCVLGNELPKFFDE
Protein: Vibrator, isoform B (A0A0B4KGG5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- LD30122p
- Oxysterol-binding protein
- Phosphatidylinositol 4-kinase alpha
- Phosphatidylinositol-3-phosphatase SAC1
Sequence:
MQIKEFRVTLPLTVEEYQVAQLFSVAEASKENTGGGEGIEVLKNEPFEDFPLLGGKYNSGQYTYKIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTVDNVHELTPDKLKVREIVHIDIANDPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKKHVNPVMTCYKLVTCEFKWFGLQTRVENFIQKSERRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKEELDKARQVGEVRGMRADAD
Protein: PUM-HD domain-containing protein (Q09487)
Organism: Caenorhabditis elegans
Interaction partners:
- Nanos-type domain-containing protein
- CCR4-NOT transcription complex subunit 7
- Female germline-specific tumor suppressor gld-1
- Nanos-type domain-containing protein
- K Homology domain-containing protein
- Poly
- Sex-determination protein fem-3
- Defective in germ line development protein 3
- Pumilio domain-containing protein 12
- HORMA domain-containing protein
Sequence:
MSRPISIGNTCTFDPSASPIESLGRSIGAQKIVDSVCGSPIRSYGRHISTNPKNERLPDTPEFQFATYMHQGGKVIGQNTLHMFGTPPSCYCAQENIPISSNVGHVLSTINNNYMNHQYNGSNMFSNQMTQMLQAQAYNDLQMHQAHSQSIRVPVQPSATGIFSNPYREPTTTDDLLTRYRANPAMMKNLKLSDIRGALLKFAKDQVGSRFIQQELASSKDRFEKDSIFDEVVSNADELVDDIFGNYVVQKFFEYGEERHWARLVDAIIDRVPEYAFQMYACRVLQKALEKINEPLQIKILSQIRHVIHRCMKDQNGNHVVQKAIEKVSPQYVQFIVDTLLESSNTIYEMSVDPYGCRVVQRCLEHCSPSQTKPVIGQIHKRFDEIANNQYGNYVVQHVIEHGSEEDRMVIVTRVSNNLFEFATHKYSSNVIEKCLEQGAVYHKSMIVGAACHHQEGSVPIVVQMMKDQYANYVVQKMFDQVTSEQRRELILTVRPHIPVLRQFPHGKHILAKLEKYFQKPAVMSYPYQDMQGSH
Protein: Vacuolar protein sorting-associated protein 52 A (AtVPS52) (ARE1-like protein POK) (Protein POKY POLLEN TUBE) (Protein T-DNA TRANSMISSION DEFECT 8) (Q94KD3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (By similarity). Required for pollen tube elongation and other polar growth.
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Note=Localized in the GARP complex in the Golgi and post-Golgi compartments.
Interaction partners:
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar protein sorting-associated protein 53 A
- Vacuolar protein sorting-associated protein 54, chloroplastic
- At2g27890
- Vacuolar protein sorting-associated protein 53 B
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 2
Sequence:
MSDISIDALGQTMGDFSNHEKLGFDLGAFVGDLAFEEDSGSEDISLEGLQQELEECESDEVVANILSSGDKLREYAKGVENNLRKVELDSIEDYIKESDNLVSLHDQIRDCDSILSQMETLLSGFQEEIGSISSDIKILQEKSMDMGLRLKNRRVAESKLAKFVEDIIVPPKMIDVIVDGEVNEEYMKTLEILSKKLKFVEADQAVKSSKALKDVEPELEKLRQKAISKVYDFIVQKLIALRKPKTNIQILQQSVLLKYKYIISFLKEHGKEVFMDVRAAYIDTMNKVLSAHFRAYIQALEKLQLDIATAYDLIGVETRTTGLFSRAREPLKNRSAVFALGDRIKIIKDIDQPALIPHIAEASSLKYPYEVLFRSLHKLLMDTATSEYMFCDDFFGEESIFYEIFAGPFSVIDEHFNPVLSNCFDAIGLMLMIRIIHHHQLIMSRRRIPCLDSYLDKVNISLWPRFKMVFDSHLSSLRDANIKTLWEDDVHPHYVMRRYAEFTASFIHLNVEYGDGQLDINLERLRMAVDGLILKLAKLFPRPKQQIVFLINNYDMTIAVLKEAGPEGGKIQMHFEEMLKSNTSLFVEELLVEHFSDLIKFVKNRASEDSSLNPERSITIAEVEPLVKDFGSRWKTAIELMDKDIITSFSNFLCGMDILRAALTQLLLYYTRLTDCIKKIDGGSALNRDLVSIQSIMYEIRKYSKTF
Protein: Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) (Q4QQS0)
Organism: Rattus norvegicus (Rat)
Function: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Interaction partners:
- Interleukin-1 receptor-associated kinase 4
- TNF receptor-associated factor 6
- Myeloid differentiation primary response protein MyD88
- Interleukin-1 receptor-associated kinase 1
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- Interleukin-1 receptor-associated kinase 3
- NF-kappa-B essential modulator
- Tumor necrosis factor receptor superfamily member 16
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
- TGF-beta activated kinase 1
Sequence:
MACYIYQLPSWVLDDLCRNIDTLSEWDWMQFASYVITDLTQLRKIKSMERVQGVSITRELLWWWSMRQATVQQLVDLLCHLELYRAAQIVLSWKPAPDSLSPLSAFPEAVKPGPVATSGRNLKDDQKKGQPVKPCSFLSSGTTMAGAQQQASCQRPCEEDAPCSLKTDVPDSLQSKYCSTSIPKQEKLLNLPGDRLFWSEADIVQATEDFDQSHRISEGTFADIYRGQRNGVAFAFKRLREVTGSSPGSMDRFLQAEMQLCLRCCHPNILPLLGFCTGRQFHSLIYPYMANGSLQDRLWAQGDSDMLSWPQRASICSGLLLAVEHLHSLDIIHSNVKSANVLLDQHLNPKLAHPVAHPCPTNKKTKYTVMKTHLFQASAAYLPENFIRVGQLTKQVDIFSCGIVLAEVLTGIPAMDKDRSPVYLKDLLLSEIPSNTSSVHSRKTSMGKVVVKEICQKHLERKAGLLPEACAETWATAVSVCLRRREASLEEARVSMAGVEEQLRGQLSLPWSRVSEDTGSSSNTPEETDDVDNSSLSVPSSVMVVSCARVSSPPPSMGNGTAQPSTSGRQEADSSSEACAGPQPPQEATETSWKIEINEAKRRLMENILLYKEEKLDSVELFGP
Protein: Decay-accelerating factor CD55 (Q9GLM0)
Organism: Sus scrofa (Pig)
Interaction partners:
Sequence:
MSPLPRSAPAVRRLMGGQTPPPLLLLLLLLCIPAAQGDCSLPPDVPNAQPDLRGLASFPEQTTITYKCNKGFVKVPGMADSVLCLNDKWSEVAEFCNRSCDVPTRLHFASLKKSYSKQNYFPEGFTVEYECRKGYKRDLTLSEKLTCLQNFTWSKPDEFCKKKQCPTPGELKNGHVNITTDLLFGASIFFSCNAGYRLVGATSSYCFAIANDVEWSDPLPDCQEISPTVKAIPAVEKPITVNFPGTKALSSPQKPSTANTLATELLPTPQEPTTVNVPDSKAISSPQKPSTVNTPATDLLPTPQEPTTVNVPDSKAISSSQKPSTVNTPATDLLPTPQEPTTVNVPDSKAISSPQKPSTVNTPATDLLPTPQEPTTVNVPAPEVPSTSQKPSTANDSAPQATSTTQRFTTAKASLTQTLRETGKSTPVHTSKTKGLQQRLTSAHVTATKYPAIPRATTSFHSSTSKNRGNPSSGMRIMSSGRACVTLTVLLMVLVTIG
Protein: Mitochondrial import inner membrane translocase subunit Tim29 (Q8WQD7)
Organism: Caenorhabditis elegans
Interaction partners:
- Mitochondrial import inner membrane translocase subunit tim-22
- Uncharacterized protein F52C9.3
- Mitochondrial import inner membrane translocase subunit Tim10
- Mitochondrial import inner membrane translocase subunit Tim9
Sequence:
MAAASVKGFFQRTGISIKEYFKRMGNDYATVARETVQGCKDRPVKAGVVFSGLGFLTYAYQTNPTELEMYDYLCERRQKLVLVPNSEHNPATTKELTARDFLISQNRLHYYNLWFFSLLVASDYNDKLRIYSSQDSNLKDWPWTELWRNIVDIGALGRWHRMETAFVDYDVNTDEIDLLPDGDKN
Protein: Protein pianissimo A (Developmental gene 1117 protein) (Protein pianissimo) (Target of rapamycin complex 2 subunit piaA) (TORC2 subunit piaA) (O77203)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function redundantly. Both proteins are integral components of the adenylyl cyclase activation pathway.
Subcellular location: Cytoplasm.
Interaction partners:
- Protein LST8 homolog
- Ras-interacting protein RIP3
- Serine/threonine-protein kinase tor
- Protein raptor homolog
- Protein kinase 2
- Probable serine/threonine-protein kinase DDB_G0288795
- DNA-dependent protein kinase catalytic subunit
- Probable serine/threonine-protein kinase smg1
- RAC family serine/threonine-protein kinase homolog
- Dual specificity mitogen-activated protein kinase kinase 1
Sequence:
MTSSDSSVNTTSSSFGNISISSPNHSSSTPPLNNGNGNNVSASETELKKHVLYSLQCLDEKTLTLKVKLDHLNKLVELKKSIPDLNKLGISPTQLYKSVRPFIALPPKTIRTAGLRVMRYYLSNSNNVKELLDLKVQYFITRSLERDKHSEPERIQALKIIRTIMEIDCSLMPHCFVKGLVSIAENQEDNFCRVCLECLTEISIRNPQISSHCGGIRTVFDAVLDPFYQGIQESLLICILYLLSDKDTRIYIRPKSDLEIILAPLTNSFNIGVKLKGASKEKEKEKEKEDEVAMKKWTASSKAVLTLIKSWIGIISLNSDDQGLKSVVDTLRMPQIELQEKALDSIFEIFRVQLPKSIQETFGPQKATQTFNFGSETLQDLPSRTRSLRHNLLNNYLSVLLIAFIDNGLIEGLVYLGNYVANRDGMSEQEKECSKNISLKSTVLLAELLHMSNALLPPSQCAKLQTLPSLVNSAISFRLDPRLRSSSNTMVTNLHSYSHNKSSTTLMDSTLAIGLTGANKWRRIKGQDRRLDKVDDVKMKMEWHMDDNQFQQKIKDTQVLVTKDYQKWSWELMFELLEGPLNNPQHLSNTLKTKFIKRILSFLRPNKKLFSTMAWTTENLKYVRTACVALEVLISHEIGFDFLKDNKTIIQIADMLKVELDYNIKPPPSSSSSSENKKDNVRLLNPEKVLKTMSREYFTMLGTLSSNLLGLEILARNNIFDYIKPLAELPGRDDLSHLIMTSLDYNVNGASRTILQKILTSSSRVVRYLATKYLRFLLRSGVQDFSNWGVELLVQQLNDVDAKVSALSLNVLDEACDDPSCLEVLIDLKPNLLKLGKPGKSLLLRFLSSPKGLENLLQNNGFVEQEEQLWITSENATYVNAIESAVSESLSPSVWRFKEAPDGSSTSGVYLPPHFFGELAKTEKGCQLIRKSNNYQRFLKIIQDPTAKQLDKRASLIAIGHIGSSVDGYSFVKESDTIKLLIGIAEKSQCLALRSTCFYALGMISCIEEAQPIFNSFGWESPSDLNSRILLPKDLKNSTFLSVPQYQYQGSWADHSFETLPSNHFSDPIKNEIISFVGNLSSHITAEGASKNLKRLKIKYPDHFATSEILNAVFILLNTFKYRLGARRFIYDLFDVAIFSSDPYHDLN
Protein: Large ribosomal subunit protein eL24B (60S ribosomal protein L24-B) (O74884)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Elongation factor 3
- mRNA export factor elf1
- Large ribosomal subunit protein eL18A
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein eS21
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
Sequence:
MKVEVCSFSGSKVYPGAGRLFVRGDNKVFRFVNKKSESLFLQRKNPRRLSWTVLYRRMHKKGISEEHAKKRTRRTVKHQRGIVGANLDVIKEKRNQRPEVRAAARAAALKQRKDKRAASESEKKAIKAKSAASSARGQAIKNAKVAARR
Protein: SCP domain-containing protein (Q9W129)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Aquarius
- Accessory gland-specific peptide 26Ab
- AT20289p
- BG642163, isoform A
- BPTI/Kunitz inhibitor domain-containing protein
- IP20609p
- glutaminyl-peptide cyclotransferase
- Accessory gland protein Acp29AB
- Serpin 28F
- Sulfhydryl oxidase
Sequence:
MFSIRVWFICLVIVTLNSFPAYSWDYCQEHWCPRSTDHVACNNNGTFGLDCGREARLIPLSNQLQAFIVHQVNFYRNQVASGGLSAFGPARRMASVRWDPELAQLAELAAKRCSLSGDGCRNTRRFKHVGQLTGHVIFSAGKHSDLELLRHKISNWFGQYMRASKDLQAADPSSNISSFRQLIQESSTHMGCGVLRQRSHMLWHQQFIVCNFARRNMPREQVYQVGVAATGCRSGRNPRYPNLCALQEEYDVNAVDRFHSKRPLRIRFKYSASHPSKVLGADRDVAFHPNIKLGRL
Protein: GTPase IMAP family member 2 (Immunity-associated protein 2) (hIMAP2) (Q9UG22)
Organism: Homo sapiens (Human)
Function: The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself.
Subcellular location: Lipid droplet {ECO:0000269|PubMed:23454188}.
Interaction partners:
- GTPase IMAP family member 7
- GTPase IMAP family member 1
Sequence:
MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFKQSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCCLLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL
Protein: Zinc finger protein 80 (ZNFpT17) (P51504)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MSPKRDGLGTGDGLHSQVLQEQVSTGDNLHECDSQGPSKDTLVREGKTYKCKECGSVFNKNSLLVRHQQIHTGVKPYECQECGKAFPEKVDFVRPMRIHTGEKPCKCVECGKVFNRRSHLLCYRQIHTGEKPYECSECGKTFSYHSVFIQHRVTHTGEKLFGCKECGKTFYYNSSLTRHMKIHTGEKPCKCSECGKTFTYRSVFFRHSMTHTAGKPYECKECGKGFYYSYSLTRHTRSHTGEKPYECLEHRKDFGYHSAFAQQSKIHSGGKNL