wanglab/gogpt-training-data huggingface dataset:
Protein: Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein) (P28062)
Organism: Homo sapiens (Human)
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Involved in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes.
Subcellular location: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
Interaction partners:
- Proteasome maturation protein
- Proteasome subunit alpha type-3
- Proteasome subunit beta type-3
- Proteasome subunit beta type-2
- Proteasome subunit beta type-9
- Proteasome subunit alpha type-4
- Proteasome subunit alpha type-5
- Proteasome subunit alpha type-6
- Proteasome subunit beta type-1
- Proteasome subunit beta type-6
Sequence:
MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
Protein: Sucrose synthase (EC 2.4.1.13) (Q9XGB7)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MAERALTRVHSLRERLDETLLAHRNEILALLSRIEGKGKGILQHHQIILEFEAIPEENRKKLANGAFFEVLKASQEAIVLPPWVALAVRPRPGVWEYIRVNVHALVVEELTVAEYLHFKEELVDGSSNGNFVLELDFEPFNSSFPRPTLSKSIGNGVEFLNRHLSAKLFHDKESMHPLLEFLRVHCHKGKNMMLNDRIQNLNALQHVLRKAEEYLGTLPPETPCAEFEHRFQEIGLERGWGDTAERVLEMIQLLLDLLEATDPCTLEKFLGRIPMVFNVVILTPHGYFAQDNVLGYPDTGGQVVYILDQVRALENEMLLRIKQQGLNITPRILIITRLLPDAVGTTCGQRLEKVYGTEHSDILRVPFRTEKGIVRKWISRFEKVWPYLETYTEDVAHEISKELHGTPDLIIGNXSDGNIVASLLAHKLGVTQCTIAHALEKTKYPDSDIYWKKLEDKYHFSCQFTADLFAMNHTDFIITSTFQEIAGSKDTVGQYESHTAFTLPGLYRVVHGIDVFDPKFNIVSPGADMEIYFPYTEEKRRLKHFHPEIEDLLYTKVENEEHLCVLNDRNKPILFTMPRLDRVKNLTGLVEWCGKNPKLRELANLVVVGGDRRKESKDLEEKAEMKKMFELIDKYNLNGQFRWISSQMNRIRNVELYRYICDTKGAFVQPALYEAFGLTVVEAMTCGLPTFATCNGGPAEIIVHGKSGFNIDPYHGDQAADILVDFFEKCKKDPSHWDKISQGGLKRIEEKYTWKIYSERLLTLTGVYGFWKHVSNLERRESRRYLEMFYALKYRKLAESVPLAEE
Protein: Low affinity vacuolar monovalent cation/H(+) antiporter (Vacuolar Na(+)/H(+) exchanger) (P42839)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a role in promoting intracellular monovalent cation sequestration via the exchange of monovalent cations and especially Na(+) for hydrogen ions across the vacuolar membrane.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:17588950}; Multi-pass membrane protein {ECO:0000269|PubMed:17588950}.
Interaction partners:
- Endosomal/prevacuolar sodium/hydrogen exchanger
- K
- Na
- Mitochondrial distribution and morphology protein 38
- Outward-rectifier potassium channel TOK1 channel YORK)
Sequence:
MAKNNHISASGNSTSGDHRLKEEVLTPTTSASTPHRIFSVDDDPKEIQNDIRYLEGLHEGLKFALHANKSKRSVSSQSPIVHSSNNTLHHHEHQQHLPPTLESLSSKSHSVPDLNTATPSSPKRMHSSIRELPHDDNDDEDANDDSRFIIHDSHGHDLLIDEINCQSPSHLENNDQASNASSTESFTLRERQDAINETHPFGIRIWKPALYKKHRSVQRTAAQDIHETQLKTITWEVTCSNVLWFILFGFPIAILFYSAAIVVFLLGGGGLVTNSAKEYSKCLYKLANYFLWPFGKMVYLLQDEQYLQEDKDEGISMQQFYNWVTSYSNRLVFHQSQAKFQQREDHPAPATESSSLMPPANTTATPLNSNHPSYNSIRHEIPHAAAQRRYFGRGKWSWGRVLFYTIFHLVLQPILAVLSLCLWLLVFTIPMSNVLWQIMYHCRRHPLALGFKYVENSSQSHENEITQQQLNKNILLCTFRAAGWHYYKYTVDGTNVIVVNLISIVFFTIFDFYVLKNFLHWKTWFTYESSIFILCLTSTIPLAFYIGQAVASISAQTSMGVGAVINAFFSTIVEIFLYCVALQQKKGLLVEGSMIGSILGAVLLLPGLSMCGGALNRKTQRYNPASAGVSSALLIFSMIVMFVPTVLYEIYGGYSVNCADGANDRDCTFSHPPLKFNRLFTHVIQPMSISCAIVLFCAYIIGLWFTLRTHAKMIWQLPIADPTSTAPEQQEQNSHDAPNWSRSKSTCILLMSTLLYAIIAEILVSCVDAVLEDIPSLNPKFLGLTIFALIPNTTEFLNAISFAIHGNVALSMEIGSAYALQVCLLQIPSLVIYSIFYTWNVKKSMINIRTQMFPLVFPRWDIFGAMTSVFMFTYLYAEGKSNYFKGSMLILLYIIIVVGFYFQGALSE
Protein: Serine repeat antigen 7 (EC 3.4.22.-) (O96163)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- Uncharacterized protein
Sequence:
MVYRLFIILVLYVICCTNVIVGQEKPPPDSTVGANPGDERESSGRVNNPASGEQGTTNSPTEQPDQTRDRSSSVPQGSPREPVSPENPNPVTQIPGNGGALVTPIPLPKLTLEDSESSKSVIDIEVKSALLKNYDGVKITGPCRSYFRVMLVPHITVYVYATYDRIQLEPKFGPSDLIDINDLTNKCNKDSNKYFKLVLYIKNNILILKWKVQDKDSKPTNIDVDVKKYKIPKLDRPFTSIQVYTVNTEHGLIESKNYDINSEIPEQCEAISTNCFLNGSLDVENCYHCTLLAKKVDSNNECFNYVSKEAKELINKNLEEKNKTFKGEDEDLDSNEQKLEESIDNILSNIYKIYESKQDKERKKSHYNNKKELVTIEELNSVLKIELLNYCKLLKEVDRSGMLDHHEIGNEIDIFNNLIRLLKAHPGESTYVLNEKLRNPALCFKNIEEWLVNKKGLLLSNEKIQNLSTTNYNVTDLEESEYDYERFISDDMFEKDMNGVIDLSLFDNEKKLKSPYFRRNKYCNNEYCDRWKDKTGCISKIEVEEQGNCGLCWIFASKLHFETIRCMRGYGHFRSSALYVANCSDRDSDEICFVGSNPVEFLEIVEETGFLPLESDVPYYYTDAGNDCPEPEKNWINLWGSTELLNHKRPRQRMTTKGYISYESSYFSDNMDLFIKIIKREIQNKGSVIAYIKTENVIDFDFNGKGVHNMCGDKEPDHAANIIGYGNYIDEEGEKKSYWLIRNSWGYYWGDEGNFRVDMYGPSYCKYNFIHTVVVFKVDLGIIEVPKKEKESEYFSYFLKYTPNFLYNLFFNNYTTNDEYKLNNRLKTNQHNNKKNKKDRYISAQDEPPTDNVESQAENNKKTEIYHILKHIKDKKIKRGLVKYESLLETKKDHSCSRTHSIDPEKHEECNQFCIDNWKACKDHYSPGYCLTKLYTKDDNCFFCNV
Protein: Trk system potassium uptake protein TrkA (Q7BV63)
Organism: Mycobacterium tuberculosis
Interaction partners:
Sequence:
MRVVVMGCGRVGASVADGLSRIGHEVAIIDRDSAAFNRLSPQFAGERVLGQGFDRDVLLRAGIQGADAFAAVSSGDNSNIISARLARETFGVPRVVARIYDAKRAEVYERLGIPTITTVPWTTDRLLNALMQDTETAKWRDPTGTVAVAEVVLHEDWVGHRATDLEQATGARIAFLIRFGTGVLPEPKTVLQAGDKVYIAAISGRAAEAAAIAALPPSEDFESGARR
Protein: ATP synthase subunit gamma (Q8I6T7)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
Interaction partners:
- ATP synthase subunit delta, mitochondrial, putative
- ATP synthase subunit alpha
- ATP synthase subunit epsilon, mitochondrial, putative
- ATP synthase subunit O, mitochondrial, putative
- ATP synthase subunit C, putative
- ATP synthase subunit beta
- JmjC domain-containing protein, putative
- V-type proton ATPase proteolipid subunit
- V-type proton ATPase 21 kDa proteolipid subunit, putative
- Cytochrome c1, putative
Sequence:
MLKPNFSSFMTRCSMLSWNTVEKKKFASDNLRSLSLRIKSVKSIQKITKAMKMVAASKFKGDQRRLEKCSNFSTPLVDVFNRLNKLDIHKKNEELAIIAISSDKGLCGSVNSSVSRLCKKLLENEQVNNELVDNITPNKIYLYGIGEKIRSALSRLHKDKFQVIYNEYNKIPINFLTCSYIAERIMNNNHSNIIIIYNHFKSAISFDTQILSVFSQKQLNKINKKELTHFEFEPEMDYIFKDIYQFYFTSILYNSIIQNLASEQSARMTAMDNASSSATDMLNALSLRYNRARQSKITLELIEIISGANAL
Protein: Probable dehydrin LEA (Q96261)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At4g38410
- Dehydrin Xero 2
- Dehydrin HIRD11
- RING-H2 finger protein ATL18
- 1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal
- Late embryogenesis abundant protein
- Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 8
- Esterase/lipase/thioesterase family protein
- At2g23110
- Late embryogenesis abundant protein 29
Sequence:
MADLRDEKGNPIHLTDTQGNPIVDLTDEHGNPMYLTGVVSSTPQHKESTTSDIAEHPTSTVGETHPAAAPAGAGAATAATATGVSAGTGATTTGQQHHGSLEEHLRRSGSSSSSSSEDDGQGGRRKKSIKEKIKEKFGSGKHKDEQTPATATTTGPATTDQPHEKKGILEKIKDKLPGHHNHNHP
Protein: L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase) (DCXR) (Short-chain dehydrogenase 21) (Q21929)
Organism: Caenorhabditis elegans
Function: Catalyzes the NADPH-dependent reduction of L-xylulose, D-xylulose, L-(+) erythrulose, D-erythrose, D-threose, L-ribulose, 1,4-dibromo-2,3-butanedione and 2,3-heptanedione. Also active against isatin, 9,10-phenanthrenequinone, menadione, 2,3-hexaenadione and 3,4-hexahenadione. No activity observed when tested using NADH rather than NADPH.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21477590}. Note=Detected on the cell membrane of spermatids. {ECO:0000269|PubMed:21477590}.
Interaction partners:
- Sorbitol dehydrogenase
- Sorbitol dehydrogenase
- Glucosidase II subunit alpha
- Adenylosuccinate synthetase
Sequence:
MPANYDFTDKRILVTGASQGIGKEICLSLAKAGAQVIAFARNEANLLSLVKETTSLRYTIIPIVGDVSANEEVLFKLIVPHFPIHGLVNNAGIATNHAIGQITQQSIDRTFAVNVRGPILIAQLVARNFVDRQIKGSIVNISSQAAIRPLDNHTVYCASKAALDMVTRCLANELGSQNIRVNSVNPTVVMTDMGRDNWSDPDKKKKMLDRMPIKRFAEVDEVVNAVLFLLSDNASMTTGSTLPVDGGFSNN
Protein: C2H2-type domain-containing protein (B5DE38)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MKQEIMAEGPRCKRRKQANPRRKNVLSYENVVDAGSGSDDEDRLLGSEGEGSPAGVPSLEASPRVAHALLSCRGDEENESQDGAGAHVWRHGELNGSEERKAEYNSMSPDISLHGIGNGTVKGIDASSELESFFAKRKLDDGEGHAASIAEYLQDTVIIYPEDPEEGTRLGTPEANGQDENENDLALRTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNDESFPCPLCSDTFAYRTQLERHMATHKPARDQPQLLNEGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECSNCKKRFSHSGSYSSHISSKKCIGLISINGRVRHGVNNKPGSSPNSAASSPGSPALAQLRHKLENGRSMSLQDPSAHTDIKSEPMDFNEYRLMIASQQEYGASGAFLNGGGRGGSPPGMHSSSQNPLQHLGIGSDSHPLGYTGFINNMSEVQKVLQIVDNTVCRQKMDGNPEEISKLRAYMKELGSQMEEQNRVLASQQSFLGVGHNSPTKTIIDYTLEKVNEAKACLQSLTEDSKRRLMDIKKERPSHAMDLLSEDKALERDAQYAPFSCQYCKETFSGPIPLHQHERYLCKMNEEIKAVLKPNDTVPTGRRGLFGSEQQAGVISSSLERNATSPVNPYKDHMSLLNVYFSMNTEPNSEELRKISMAVGLPQEFVKDAFVQWKAQSHHSFSRKRSPPPERSGETNHVRDSAFARSPVSLGQYGDSTAEIQAITNGDSGHKLSRTHQITGTRQTNEKPLDSVDHLRGETPSPLNLSSSSSKHSHSSSYTPNSLTSEDAHGEPLDLSLPKQVSKAERRAKPNGFSIEHTSNSTAREPGTEPLNLAHIKKEFNGPNSLGNENQMDKSSSPIFSINPFGGGHMYTSLPPHGAFPPPTFMSTTQASIPGLRPYPGLDPMSFLPPMAYTYAAGAATFAEMQQRRKYQRKQGFQGDLLDSAGDYLSGLEDLTDSESLLARKKIKKTESGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAKQENHNNGGPLEPTELLMRRAYLQGLGPLGFSDPEDQAEDITRENTILRDGTESGARETEETYAEVTDRQETGLMGEEEMEGQRFDTRSPDGTAKDEKESEVTGGTEDESSEEGKRNPDGENEDAD
Protein: Prohibitin-1 (Q9P7H3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Has an antiproliferative activity. Regulates replicative life span (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P40961}; Peripheral membrane protein {ECO:0000250|UniProtKB:P40961}; Intermembrane side {ECO:0000250|UniProtKB:P40961}. Cytoplasm {ECO:0000305|PubMed:16823372}.
Interaction partners:
- Prohibitin-2
- Mitochondrial inner membrane m-AAA protease component yta12
- ATP-dependent zinc metalloprotease YME1 homolog
- Non-selective voltage-gated ion channel
- Uncharacterized protein C16G5.07c
- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase
- Large ribosomal subunit protein bL35m
Sequence:
MAVVLERVARYAIPIGIGFTLLQSSIYDVPGGKRAVLFDRLSGVQKQVVQEGTHFLIPWLQKAIVYDVRTRPRNIATTTGSKDLQMVSLTLRVLHRPEVGMLPQIYQNLGLDYDERVLPSIGNEILKSVVAQFDAAELITQREVVSAKIRQELVQRATEFGIRLEDVSITHMTFGKEFTKAVERKQIAQQEAERARFLVEQSEQERQANVIRAEGEAEAADIVSKALDKAGGALIQIRRLETSKEVATALANKGAQVTYLPFGAGSNAQSSSGSGLLLNVNP
Protein: EDAR-associated death domain (Ectodysplasin-A receptor-associated adapter protein isoform X1) (E7F388)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Ectodysplasin A receptor
- Ectodysplasin A
- Paired box protein Pax-9
Sequence:
MCETIVLNMTSLKAFTEPFGRVASEPVEDTDPSSFITDMSLRSNYPVQVTDSQDPVTLQLSSVPPGFLSSAVGRIRQPVENDDSECITSASVSSDFSKELKPCKEGLFSAPPPKISDLMNDEDLLYSLRLKLDPTHCTVKNWKNFASRWGMSYDELMLLEQRKHGATYNSPTQEFLLRYNQKPVTELTELCQLYQRIDVLRLLQRWMENDWPSRWQKAH
Protein: Myosin 28B1, isoform A (EC 5.6.1.8) (Q9VLZ3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSEFVRQHGEYVWVKPQNTTSEFAVPFGARIVRTEKTQTLVCDDRNKQFWVPAGDVLKAMHITSQEDVEDMITLGDLQEYTILRNLQNRYAKQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPHIFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLAAISGKHSWIEQQIIEANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFYCMLAGLSTAERERLKLQEQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSILSLLAAILHLGNLRFTATEVANLATAEIDDTPNLQRVAQLLGIPISALNAALTQRTIFVHGEHVTTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNSIGVLDIFGFENFDNNSFEQLCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEESKFPKGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQRSTNKYLVDIFPHEMPMDTAKKQPTLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNFDKELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPVGPLEQCDCRKLARQICEVALPADSDRQYGKTKLFLRDEDDASLELQRSQLMLKSIVTIQRGIRRVLFRRYMKRYREAIITVQRYWRGRLQRRKYQVMRQGFHRLGACIAAQQLTTKFTMVRCRTIKLQALSRGYLVRKDFQKKLLERRKQNQLKKEELLKLAKMKEAEELLRLQQLKEQKEREQREQQEKRLQEEQRLKAEAAARNALAMAAVQQKRRTKPVKQEAPKAPTLQARNSLPPPPTTLIVAAPLPTRPASAVTRINTIPESPGTIDVESSKQMVDDVFRFLNDEPDAALRKLNNISSGDTIRLPKSVPNNIDTSDFSYLKYAATYFGGGATAQHERKPLKKSLLKHEHPIDEMASKAIWLTILRFMGDLPDVVSSPTLHVFDNENLMSDLASLLNTSDSYKPRLFVRQSQRRIPKPLASGEKEAQEFYQHWLNVPTSHLEKIHFIIGHGIIKNSLRDEILAQICKQLYLNPSRSSYSRGWLLLSLCLSCFPPSKEFEPHLRSFMKQGTAQLQATPSLQRLERTLVNGPRCQPPSLFELHAIRGRHPLRLDIHLMDGQQRRLQVDAASTAREAVNQLCQGMGLTDTFGFGLVMSLNGKLMPLGAGQEHVLDAISECEQRQLDAPWKLYIRKEMFATWYDPSMDPKATQLIYKQILNGLKCGEYRCRSEKDIAMVCALACFVEYGPGEILRLKPSEITAFVPSDLLAPGERAIENWSRLIAATYEKSSYVKEEQNDLLLEAQKRAKEDICLFAHLSWPMRHSRLFEVVRKEGPKLQSDELMLGINSAGLFLIDETEQVLASCCFSEVLKVHVESDDKLHVMTFQHVNFVLQCSSAQDANEVINYMLDNLRQRSSYGVALDPVVEGDLEDCLVLNPGDLIEFEAGVTGAQLMAGNAQDCYRGCVNGQWGQFLAGNVRVLATLTKPSEKLQDILREGRFQEPPKPTPRANYSRRRQHNISQLAESHFREPLDSDKAPLSKFSPEPLKAPLLKAVVKVPPLFQQALVMHHHILKYMGDIARSNLPVNTDLIFQPALQHPLLCDELYCQLMKQLSDNPSSESEKRGWDLLYLATGLVAPSVLVMRELIILLRMRADALADACLKRLKRSLAQGQRKKAPHLIEVEGIQQRCLHIYHKIYFPDDTVEAFEIESHTRGAELIADIAQRLELKSPVGYSIFLKTGDRVYAMPEEEFVFDFITQLIYWLRQQRTIRSISDGQYQLHFMRKLWLNNHPGEDLNGDMIFSYPQELHKYLKGYYPIDCEQASRLAILVYSADHDVSLQRLPEVLTRLIPEDLIPLQTVAEWRQQILPKVHRDHLTEDHAKILFLQELSHFACFGSTFFVVKQQNDDALPETLLIAINSTGFHMLDPTTKEILRSYEYSQLGIWSSGKNHFHIRFGNMIGASKLLCSTTQGYKMDDLLASYVKYFNEHE
Protein: N-alpha-acetyltransferase 40 (EC 2.3.1.257) (Histone-specific N-acetyltransferase NAT4) (Q04751)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- N-alpha-acetyltransferase NAT5
- N-terminal acetyltransferase B complex catalytic subunit NAT3
- Histone H4
- N-alpha-acetyltransferase 30
- N-terminal acetyltransferase A complex catalytic subunit ARD1
- N-terminal acetyltransferase B complex subunit MDM20
Sequence:
MRSSVYSENTYNCIRTSKEHLTERRRVAMAPMFQHFLNLCVEKFPESIEHKDTDGNGNFTTAILEREIIYIPEDDTDSIDSVDSLKCINYKLHKSRGDQVLDACVQLIDKHLGAKYRRASRIMYGNRKPWKANKLAEMKSAGLVYVCYWDNGVLGAFTSFMLTEETGLVEGDALHEVSVPVIYLYEVHVASAHRGHGIGRRLLEHALCDGVARHTRRMCDNFFGVALTVFSDNTRARRLYEALGFYRAPGSPAPASPTIRHTRHGGGRVVVPCDPLYYVYCLHMP
Protein: Recombination-promoting nuclease RpnC (EC 3.1.21.-) (P31665)
Organism: Escherichia coli (strain K12)
Function: A low activity DNA endonuclease yielding 3'-hydroxyl ends (Probable). Upon expression enhances RecA-independent DNA recombination 2.9-fold, concomitantly reducing viability by 59% and inducing DNA damage as measured by induction of the SOS repair response.
Interaction partners:
Sequence:
MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTLHLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAMHRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITITPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQRGHTEQADLFYGVLRDRETGGESMMTLAQWFEEKGIEKGIQQGRQEVSQEFAQRLLSKGMSREDVAEMANLPLAEIDKVINLI
Protein: Eyes absent homolog (EC 3.1.3.48) (E7ETN2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Protein: Integrator complex subunit 2 (Q9VX31)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity).
Subcellular location: Nucleus membrane {ECO:0000250|UniProtKB:Q9H0H0}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000269|PubMed:39032490}.
Interaction partners:
- Integrator complex subunit 5
- Integrator complex subunit 1
- Integrator complex subunit 7
- Integrator complex subunit 3
- Integrator complex subunit 4
- Integrator complex subunit 6
- Integrator complex subunit 8
- Integrator complex subunit 11
- Integrator complex subunit 9
- Protein asunder
Sequence:
MPVRMYDVSPRVFCAMQNLDITLLASYPEAEIRPVLPSLVRMSLLSPLDNTESSMESRKEILAVLIGIEVVNSIVSYLQVNYHELENELKKELQARQKSAFFEGQQHEYGLQSGIALGFERADVARKVRVVLSEIFNLQQQVSEQKPAAHSEMLDDGIYLEEVVDILCIALAELPSLLNILELTDALVHVPNGHRIICALVANFPDCYRDVVSHVIANCDEDGSDGKHRLMLLMGLSEMNPSQALANRSMCVDMLKVPSFMLKLTLKHPEDLIAFLTGLLLGNDQNLRSWFAAYIRSSQKRKGDALNLVRVELLQKVIQTTTNAAELRDFNLQGAVLLRLYCALRGIGGLKFNDDEINALSQLVTSCPQATPSGVRFVTLALCMLIACPSLVSTIPLENKAVEWLQWLIREDAFFCKRPGTSTSLGEMLLLLAIHFHSNQISAISEMVCSTLAMKIPIRPNSTNRIKQLFTQDLFTEQVVALHAVRVPVTPNLNGTILCYLPVHCIQQLLKSRTFLKHKVPIKSWIFKQICSSVRPVHPVMPALVEVFVNTLIIPNPTGKVNIDHMHRPFTEAEILHVFRTSKLTFFAEELPPMAESQELNQIEVTCPLTAQLLMIYYLMLYEDTRLMNLSALGGRKQKEYSNNFLGGLPLKYLLQKAHHYHNDYLSLFHPLLRLIISNYPHLSMVDDWLEEHNLAQGNSTVVVSKHELKPETLDRALAAIQTKPHLAIRVFKQLLQMPPETQAQYGQQLVKHLPMVFAKSVPRYVKDLYNDIWLRLNAVLPTTLWIMSLRAITNGSDTMDRRTFANESLLEPMEVLSCPRFVFCSPYLLMILLRILKGSLAASKTYLNVHMQMQQKQVLDKNGMMQTDAIWEDLRTTLIASQESAAVHILLEVLDYIASKATDRVSHLELREIQGIIGTYVHQAFISEPSLAKLVHFQTYPKSVIPMMVASVPSMHICIDFVHEFLNVTEMEKQIFTIDLTSHLVLNYSIPKSLGVSKFCLNVIQTTLSMLTASTKCRFLRNVMPAMVRFVETFPILADDCVNILMTTGRILHSQSSLGMTTMEMPLTDSDKLCTYRDAQLHIIMIEDAFKALVTAVMKKSDLY
Protein: IP08727p (Rab at 9Fb) (Q8IR98)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Exocyst complex component 6
- CG2885
- FI01544p
Sequence:
MSQYDYLFKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDERFKSLLPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSSESVNVMLVGNKCDDLDNRQVRMEQGFNYANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRLVIHTPNRLSGGQETEDTAEPPDEPINLAGKDRQRAKDSNTCC
Protein: Ensconsin, isoform J (M9PBN6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASLGGQHGNISTNPEVENTAKRPESREGSAERKDREEKLKYARDRQNEERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKAIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDRQDGRAYSMNRLDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSAGSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQRDSTSSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTITKPAPAPVAPTSAPVPEQNGVAKEVEKTTADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEEGARQEEEQILAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAATAPENNSSSNSSVTGSSNNSAEGSPSAADSTPAPTATETVQEAPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNGKLLVDFESTNTVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL
Protein: Transcription factor Sox-2 (Q6P0E1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:16543359, ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16543359}.
Interaction partners:
- POU domain, class 5, transcription factor 1
- Kruppel-like factor 4.
- Biklf
- Transcriptional regulator Myc-A
- Catenin beta-1
- Nanog
- Paired box protein Pax-6
- Homeobox protein OTX2
- Protein lin-28 homolog A
- Glial fibrillary acidic protein
Sequence:
MYNMMETELKPPAPQPNTGGTGNTNSSGNNQKNSPDRIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNGMGAGVGVGAGLGAGVNQRMDSYAHMNGWTNGGYGMMQEQLGYPQHPSLNAHNTAQMQPMHRYDMSALQYNSMTNSQTYMNGSPTYSMSYSQQSTPGMTLGSMGSVVKSESSSSPPVVTSSSHSRAGQCQTGDLRDMISMYLPGAEVQDQSAQSRLHMSQHYQSAPVPGTTINGTIPLSHM
Protein: Pre-mRNA-splicing factor SLU7-A (Protein SWELLMAP 1) (Q9SHY8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- Pre-mRNA-splicing factor SYF2
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7
- At1g80930/F23A5_23
- Initiation factor eIF-4 gamma, MA3
- 7-dehydrocholesterol reductase-like protein
- Pre-mRNA-processing factor 17
- Transducin/WD40 repeat-like superfamily protein
- Pre-mRNA-splicing factor 18
- Pre-mRNA-splicing factor 18
- Cell division cycle 5-like protein
Sequence:
MATASVAFKSREDHRKQIELEEARKAGLAPAEVDEDGKEINPHIPQYMSSAPWYLNSEKPSLKHQRKWKSDPNYTKSWYDRGAKIFQAEKYRKGACQNCGAMTHTAKACMDRPRKIGAKYTNMNIAPDEKIESFELDYDGKRDRWNGYDPSTYHRVIDLYEAKEDARKKYLKEQQLKKLEEKNNNEKGDDANSDGEEDEDDLRVDEAKVDESRQMDFAKVEKRVRTTGGGSTGTVRNLRIREDTAKYLLNLDVNSAHYDPKTRSMREDPLPDADPNDKFYLGDNQYRNSGQALEFKQLNIHSWEAFDKGQDMHMQAAPSQAELLYKSFQVAKEKLKSQTKDTIMDKYGNAATEDEIPMELLLGQSERQVEYDRAGRIIKGQEVILPKSKYEEDVHANNHTSVWGSYWKDHQWGYKCCQQIIRNSYCTGSAGIEAAEAALDLMKANIARKEATEESPKKVEEKRMASWGTDIPEDLELNEEALANALKKEDLSRREEKDERKRKYNVKYNNDVTPEEMEAYRMKRVHHEDPMKDFL