wanglab/gogpt-training-data huggingface dataset:
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) (GCN5-like protein 1) (Protein acetyltransferase BLOC1S1) (EC 2.3.1.-) (O55102)
Organism: Mus musculus (Mouse)
Function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. The BORC complex is most probably associated with the cytosolic face of lysosomes, may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (By similarity).
Subcellular location: Mitochondrion intermembrane space {ECO:0000269|PubMed:22309213}. Mitochondrion matrix {ECO:0000269|PubMed:22309213}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P78537}. Lysosome membrane {ECO:0000250|UniProtKB:P78537}.
Interaction partners:
- Biogenesis of lysosome-related organelles complex 1 subunit 3
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- SNARE-associated protein Snapin
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- Dysbindin
- Biogenesis of lysosome-related organelles complex 1 subunit 4
- BLOC-1-related complex subunit 8
- Biogenesis of lysosome-related organelles complex 1 subunit 5
- KxDL motif-containing protein 1
- BLOC-1-related complex subunit 5
Sequence:
MLSRLLKEHQAKQNERKELQEKRRREAIAAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKGQLQSAPS
Protein: EaeB (EspB) (Secreted protein EspB) (Translocon EspB) (Type III secretion system LEE translocon pore-forming subunit EspB) (P71213)
Organism: Escherichia coli
Interaction partners:
Sequence:
MNTIDYTNQVMTVNSVSENTTGSNAITASAINSSLLTDGKVDVSKLMLEIQKLLGKMVRILQDYQQQQLSQSYQIQLAVFESQNKAIDEKKAAATAALVGGAISSVLGILGSFAAINSATKGASDIAQKTASTSSKAIDAASDTATKTLTKATESVADAVEDASSVMQQAMTTATRAASRTSDVADDIADSAQRASQLAENAADAAQKASRASRFMAAVDKITGSTPFIAVTSLAEGTKTLPTTVSESVKSNHEISEQRYKSVENFQQGNLDLYKQEVRRAQDDIASRLRDMTTAARDLTDLQNRMGQSVRLAG
Protein: Amino acid transporter 1 (Q9P5N2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Probable amino acid transporter that may play a role in function in microtubule organization since it causes microtubule defects when overexpressed.
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=When the cells were shifted to a nitrogen-free medium, aat1 was transported from the Golgi apparatus to the plasma membrane within 30 minutes.
Interaction partners:
- Uncharacterized protein C18H10.20c
- E3 ubiquitin-protein ligase pub1
Sequence:
MSAKDYDFDIESVLPEEKAPQVSEAKKDYISQESTVLSGQVDFVEPEHKGFFQNLIDGFKPAREADGNGGPALKRGLSTRHMQLMSIGGAIGSGLYVGSGSALADGGPASVIINYILIGIMMFFVIYALGEMAVAYPVAGSFNTYATRFIDPAWGFAVSWNYFFNYFVTFPFELTTCAITFTFWTDVNCAVWISIFLVVVIGINLFGVRVFGEVEFVLALIKVVATVGFIILAIIINCGGVPTDHRGYIGGSIIKQKPFRHGFKGFCSVYTTAAFSFSGTEIVGLAAAEVGDPRKTLPGAVKQVFWRVAIFYIVSLILIGLLISPDDPKLMGNGSASVSPFVLAIQEANIKGLPSVFNAVIIISVISVTNSSTYTAGRTLHGMANLKQAPAFFKYTDRLGRPLIAMIVVLSFGFFAYINEANNNGNDISDTVFDWLLAISGLSNFFTWGSICLSHIMFRLAFKKQGHSLKELGFVSPMGIWGSVIGLGFNILCLMAEFYVSLFPIGGSPNANDFFQGYLAACITLVFFIGYKIYDRSHIPSLDKLDITTGLKTYEYEETKDSSDTGRFRFFKKIINTVC
Protein: U-box domain-containing protein (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PUB) (Q9M8S5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Glutathione S-transferase U25
Sequence:
MVLPWRSRGGVAKRRNQLISGDISVVETKIPVQLRSPSRIERIQSPRVLLTPRDAVEISRRLQNAAAREEYAECLEIVSKIKNLGRGGDTNKKCLVQNGSVLALSSCFERFAAARDGHMRLLEEILFVLSSWLPLNRSEGFNKMGSTASLNCLVRFLNGKDAKTRQNAAFCIREVIAVDKRYVYALTDVEGACEGLVKIIRDSVSTSSTKASLMVIYRAISSNDKITEKFVKLGLVELITEMMVNNAEKSVCERSLVVLNATCDNEQGKEDVLRNALIVPLLVKKILRVSDLATQCSVSILWKLWKNKKDGECDDRLLVEALQVGAFEKLLVLLQVGCEDKTKEKASELLRNLNRCRNEIEKTNCVDSSMHLKNVKKSF
Protein: CASP-like protein 5A2 (AtCASPL5A2) (Q9SKN3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:24920445}; Multi-pass membrane protein {ECO:0000269|PubMed:24920445}.
Interaction partners:
- Protein OXIDATIVE STRESS 3 LIKE 4
- LIMR family protein At5g01460
- RING-type E3 ubiquitin transferase
- Putative RRM-containing protein family protein)
- Protein RALF-like 31
- Nuclear polyadenylated RNA-binding protein
- Ternary complex factor MIP1 leucine-zipper protein
- Protein OXIDATIVE STRESS 3 LIKE 3
- Choline transporter-like protein
- Phosphatidylinositol 4-kinase gamma 7
Sequence:
MNVSHASVHPVEDPPAAATEVENPPRVRMDDMEGMPGTLLGLALRFFQFLFAAAALCVMASTSDFPSVTAFCYLVAATGLQSLWSLALAMVDVYAIMVKRSLQNRRLVSLFAIGDGVTSTLTFAAACASAGITVLIDNDLNSCAQNHCVQFETSTALAFISWFAALPSFLFNFWSLASR
Protein: Glucokinase (EC 2.7.1.2) (Glucose kinase) (P54495)
Organism: Bacillus subtilis (strain 168)
Function: An ATP-dependent kinase that phosphorylates glucose to make glucose-6-phosphate, not active on fructose, galactose or mannose. Restores glucose kinase activity in E.coli glk mutants.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:9620975}.
Interaction partners:
- PTS system glucose-specific EIICBA component
- Glucose-6-phosphate isomerase
- Putative phosphotransferase enzyme IIA component YyzE
- Phosphotransferase enzyme IIA component PtsA
- Aldose 1-epimerase
- Phosphoglucomutase
- Uncharacterized protein YqgQ
- Aryl-phospho-beta-D-glucosidase BglH
- Aryl-phospho-beta-D-glucosidase BglA
- 6-phospho-beta-glucosidase GmuD
Sequence:
MDEIWFAGIDLGGTTIKLAFINQYGEIQHKWEVPTDKTGDTITVTIAKTIDSKLDELQKPKHIIKYIGMGAPGPVDMAAGVVYETVNLGWKNYALKNHLETETGIPAVIENDANIAALGEMWKGAGDGAKDVILVTLGTGVGGGIIANGEIVHGINGAGGEIGHICSIPEGGAPCNCGKTGCIETIASATGIVRIAKEKIANAKKTTRLKATEQLSARDVFEAAGENDEIALEVVDYVAKHLGLVLGNLASSLNPSKIVLGGGVSRAGELLRSKVEKTFRKCAFPRAAQAADISIAALGNDAGVIGGAWIAKNEWLKHQNC
Protein: L-threonine 3-dehydrogenase (L-ThrDH) (TDH) (EC 1.1.1.103) (L-threonine dehydrogenase) (O58389)
Organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate. Is much less efficient when using NADP(+) instead of NAD(+). To a lesser extent, also catalyzes the oxidation of L-serine and DL-threo-3-phenylserine, but not that of L-allo-threonine, D-threonine and D-allo-threonine and many other L-amino acids.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00627}.
Interaction partners:
- 8-amino-7-ketopelargonate synthase
- 346aa long hypothetical threonine synthase
- Threonine synthase
- Threonine synthase
- 273aa long hypothetical morphine 6-dehydrogenase
Sequence:
MSEKMVAIMKTKPGYGAELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGPGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGVDTDGVFAEYAVVPAQNIWKNPKSIPPEYATLQEPLGNAVDTVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAVTPAGRVSLLGLYPGKVTIDFNNLIIFKALTIYGITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFMLK
Protein: POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1) (Q29076)
Organism: Sus scrofa (Pig)
Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530}.
Interaction partners:
- POU domain protein
- Uncharacterized protein.
- Sp1 transcription factor
Sequence:
MNNPSETSKPSMESGDSNTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQPSVQAAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLGHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSALCSPSALNSPGLGVEGLNRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVGTTPSLVTSSAATTLTVNPVLPLTSAAVTNLSVTGTTDTTSNNTATVISTAPPASSAVTSPSLSPSPSASGSTSEVSSASETSTTQTTSTPLSSPLGTSQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPGLMAPSQFAAGGALLSLNPGTLGGALSPALMSNSTLATIQALASGGSLPITSLDATGNLVFGNAGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASAGNSGPVASLHATSTSAESIQNSLFTVASASGAASTTTTASKAQ
Protein: Uncharacterized protein (Q382H1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSHPKMKLVRRARKSIRERRMKACLKDLSSNLEKVEMRVFRQQKQKRQQQQRKGAGNHITVPPDVLRGVMNPELYHIECRLHQEACMPPPPPYEGYSQRERCDGARRRIGFVEFVTIAEMVRLGAMPGTPARVGI
Protein: Lipopolysaccharide assembly protein A (P0ACV4)
Organism: Escherichia coli (strain K12)
Function: Involved in the assembly of lipopolysaccharide (LPS).
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01948, ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:24722986}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01948}. Note=Copurifies with LptE/LptD, LptBFGC, LptA, DnaK/DnaJ and LPS. {ECO:0000269|PubMed:24722986}.
Interaction partners:
- Lipopolysaccharide assembly protein B
- Phosphatidylglycerophosphatase B
- Adenylate cyclase
- Probable autotransporter YfaL
- UPF0352 protein YejL
- Lipopolysaccharide export system protein LptC
- Protein SprT
- Negative modulator of initiation of replication
- Anti-sigma-E factor RseA
- Outer membrane protein assembly factor BamC
Sequence:
MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTLLAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
Protein: Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (EC 1.3.1.124) (Q9LTV6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA (By similarity).
Subcellular location: Peroxisome {ECO:0000269|PubMed:17951448}.
Interaction partners:
- 2,4-dienoyl-CoA reductase [
- Peroxisomal adenine nucleotide carrier 1
- Acyl carrier protein 1, mitochondrial
- Armadillo repeat only 3
- Enoyl-CoA delta isomerase 1, peroxisomal
- Phytyl ester synthase 2, chloroplastic
- Strigolactones hydrolase CXE15
Sequence:
MDSPFKPDVVRGQVALITGGGSGIGFEISSQFGKHGASIAIMGRRKQVLDDAVSALRSLGIQAIGLEGDVRKQEDARRVVEATFQHFGKLDILVNAAAGNFLAAAEDLSPNGFRTVLDIDAVGTFNMCHAALKYLKKGAPGRDSSSGGGSIINISATLHYTASWYQIHVSAAKAAVDATTRNLALEWGTDYDIRVNGIAPGPIGGTPGMSKLVPEEIENKTREYMPLYKVGEKWDIAMAALYLSCDSGKYVSGLTMVVDGGLWLSKPRHLPKEAVKQLSRAVEKRSRAKPVGLPTSKL
Protein: COP9 signalosome complex subunit 2 (Signalosome subunit 2) (O01422)
Organism: Caenorhabditis elegans
Function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the meiosis to mitosis transition via deneddylation of cul-3.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12781129}. Nucleus {ECO:0000269|PubMed:12781129}.
Interaction partners:
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 5
- COP9 signalosome complex subunit 6
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 3
- Cullin-2
- RING-box protein 1
- Uncharacterized protein
- Cullin-4
- Ubiquitin-like protein NEDD8
Sequence:
MGDEYMDDDEDYGFEYEDDSGSEPDVDMENQYYTAKGLRSDGKLDEAIKSFEKVLELEGEKGEWGFKALKQMIKITFGQNRLEKMLEYYRQLLTYIKSAVTKNYSEKSINAILDYISTSRQMDLLQHFYETTLDALKDAKNERLWFKTNTKLGKLFFDLHEFTKLEKIVKQLKVSCKNEQGEEDQRKGTQLLEIYALEIQMYTEQKNNKALKWVYELATQAIHTKSAIPHPLILGTIRECGGKMHLRDGRFLDAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLIKSDINPFDSQEAKPFKNEPEIVAMTQMVQAYQDNDIQAFEQIMAAHQDSIMADPFIREHTEELMNNIRTQVLLRLIRPYTNVRISYLSQKLKVSQKEVIHLLVDAILDDGLEAKINEESGMIEMPKNKKKMMVTSLVVPNAGDQGTTKSDSKPGTSSEPSTTTSVTSSILQGPPATSSCHQELSMDGLRVWAERIDSIQSNIGTRIKF
Protein: Transcriptional regulator gntR family (Q8PAI3)
Organism: Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Interaction partners:
- ABC transporter ATP-binding protein
- ABC transporter permease
- Putative auto-transporter adhesin head GIN domain-containing protein
- DUF2884 family protein
Sequence:
MTDIQWSDGAPIYRQLKERVIAMMLDGILKPGDALPSVRQVAADYQLNPITVSRAYQELADENLVEKRRGLGMFMTPEAAQKLRGSERERFLNEEWPAVLERIQRLGLTIDDLLPQGKTP
Protein: Phosphatidylinositol transfer protein beta isoform (E7EZR3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004394}.
Interaction partners:
Sequence:
MVLIKEYRVVLPCSVEEYQVGQLFSVAEASKNETGGGEGIEVLKNEPYEKEGEKGQYTHKIYHLKSKVPGFVKMIAPEGALVFHEKAWNAYPYCRTIVTNEYMKDDFMIKIETWHKPDTGALENVHDLDPITWKTVEVVHIDIADRSQVEPGDYKPEEDPEIFHSEKTGRGPLGPDWKKELLAKPDSPRMCAYKLVTVKFKWWGLQTKIENFIHKQEKRIFTNFHRQLFCWIDNWVELTMEDIRRMEEETQRELEEMRQKGNVRGTTASEE
Protein: ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2) (Q63563)
Organism: Rattus norvegicus (Rat)
Function: Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Subcellular location: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Interaction partners:
- ATP-sensitive inward rectifier potassium channel 8
- ATP-sensitive inward rectifier potassium channel 11
- ATP-binding cassette sub-family C member 8
- ATP-sensitive inward rectifier potassium channel 1
Sequence:
MSLSFCGNNISSYNIYHGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSQRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGMSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNEPKNNTTRFSETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDNYEQARRLRPAETEDVAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSSFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINDPGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLIALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK
Protein: Nucleophosmin (Q9SU93)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable nucleolar protein 5-2
- Protein LURP-one-related 9
- Protein SHORT ROOT IN SALT MEDIUM 1
- Guanine nucleotide-binding protein-like NSN1
- Nucleolin 1
Sequence:
MVVMNRVLVALTLALLASSALLPVSDAAKKPSSTPRKEDVPYIKCQVCEKLSSRLHQLVKEKQQQISPKKISEYEIIEIAENVCNLKKEEADWMLKIDIVEKGDNLVLVEQQEEGMCNSKCKTIENACQKVIGYSDTDVAEYIYKSKPDLVSLVNHLCKDLTDACSKKPPPVPKDRVPGEPFVAKPSKDAEMDKILRSMQGMPGAPGMKVYSREDIEKGNIGNEDDDGDDDEDEEEDDKFPKNLGKVLKEKESKTEELKKTITKEFKKKGEALKRHAQKVSNRVRRWWKGLGSSSSKKPKSGKSEL
Protein: Fet99p (A0A1D8PPE6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Fth1p
- Fth2p
- High-affinity iron permease
- Ftr2p
Sequence:
MRFIVSSFIFFISFLSSLITAETHTWYFKTSWVDANPDGVFPRKMIGFNDSWPLPTLRAKKGDRIQLYLINGFEDLNTTLHFHGLFQHGTNQMDGPEMVTQCPIPPGETYLYNFTIDDQVGTYWYHSHTSGQYGDGMRGVFIIEDDDFPYDYDEEIVLTLSEHYHDYSKDLMPGFLSRFNPTGAEPIPSNILFNETRNNTWKVEPGKTYLLRIANTGRFVTQYLWMEDHEFTVVEVDGVYVEKNTTDMLYITIAQRYGVLITTKNSTDKNYAFMNRVDDTMLDTIPKDLQLNGTNYIVYNESAPLPDAYDVDSIDDYLDDFYLKPLNKEKLLDDADYTITVDVQMDNLGNGVNYAFFNNITYMTPKVPTLLNVLSAGDASTNELVYGSNTNSFVLQGGDVVDIVLNNLDTGRHPFHLHGHVFQLIERHEEIPDTEDPVSYNVSDHAEWPEYPMSRDTVYVKPQSYIVMRFKADNPGVWFFHCHIEWHLDQGLAIVLIEDPEAIQKNSSQHLTDNHKQICEKVGVSWEGNAAANSNNYLDLKGENIQVKRLPTGFTARGIVALVFSCIAAFLGIAAIAYYGMNDIEDVEERVARDLDVDLDEENEDEEEAEIVNEGSSSSGSNSKQH
Protein: Peroxiredoxin-like 2C (AhpC/TSA antioxidant enzyme domain-containing protein 1) (Thioredoxin-like protein AAED1) (Q7RTV5)
Organism: Homo sapiens (Human)
Function: May regulate positively ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis.
Interaction partners:
Sequence:
MAAPAPVTRQVSGAAALVPAPSGPDSGQPLAAAVAELPVLDARGQRVPFGALFRERRAVVVFVRHFLCYICKEYVEDLAKIPRSFLQEANVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEEIASSGQSPHIKSNLLSGSLQSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFIHRDRNRLDHKPINSVLQLVGVQHVNFTNRPSVIHV
Protein: Uncharacterized FAD-binding protein C12C2.03c (Q09744)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Sulfite reductase subunit beta
Sequence:
MAPSVATSLKAEILPSPRTSSPSSNFKTCVSNENGCINCRCSPSEPHESANVDESVNKLSKTFSKLSLNPTFQALNMDLGLLHENITLDRIPKVPENHVSLIDIDEARAKEDPNFQIHSTPSRMPPHYVQPHPPFSVFPAPILDVRELTKPGAVKRVFHFELDVSNYPLPEGEEWMVGGSFGVMAPNNEEDVDELLQLLHINPDQADAPVLLKTDGGRWPTIWAEDTPRELVTTRRELLKWTVEFMSVAPKKQLIRLLAEYAKDDTERQVLLFLVSRLGQRAFCDLRDHNVTLITLLKAFPSVQLPLDHLLTVLPQLMPRWYSLSNDPKVSNNVLEFAVTVVEINKVEGGTRSGIGSGFLKRLALRFLNGERDLVLPMYRGLHKNAFATHFASDGPMCLIGAGVGVAPFRGFVQRRLTNATCAGKVWVFHGCRDQELDELYHGEWENPLQKSSDDDASSTVSQQTETEMDSFEVKKDGTSGPNHLVVESRSHQHAYVQDEIRHRGDIVWSVLSHPHGKVYLCGGKKGFLDGVENALIDVCVQYGKMSRLEATQQLALWQSPLNLKYIKEIW
Protein: Nogo receptor homolog 2a (Reticulon 4 receptor-like 1) (Reticulon-4 receptor-like 1b precursor) (Q6WZD2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Cell projection {ECO:0000256|ARBA:ARBA00004316}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}.
Interaction partners:
Sequence:
MFKRGCGLEFLLVLCGLELSWSCPRHCICYMAPSTVSCQAHNFLSVPEGIPPHSERIFLQNNKIHRLLQGHFSPTTVTLWIYSNNITYIEPSTFQGFTLLEELDLGDNRYLRSLSAETFHGLGRLHALHLYRCGLSALPNNIFQGLRNLQYLYLQDNHLEYLQDDLFVDLHNLSHLFLHGNRLWSLHQNTFRGLGALDRLLLHHNQLQWVDRLAFHDLRRLTTLYLFNNSLTELAGECLTQLPALEYLRLNDNPWECDCKALSLWDWLKKFRGSTSSVGCVAPAELAGKDLKQLRKEDFPNCSGSESLHQSKTNTWAGTNKVSLKQEPHPAQPPQTHPHHPQLNEQFPSPPSPLPQPPPAINGVQVVPGVSPDMIPDQRPGRSRNCTRQRVRGSKGKGPNEVHILKEMADKEYSSPDFTGKYDETSSNGSNTRRKHKCTPRTSVRPPSGVQQATNLGHSHHTHLFLCSISGLLTLILR
Protein: High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7) (Q8BGY9)
Organism: Mus musculus (Mouse)
Function: Transmembrane transporter that imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion-dependent.
Subcellular location: Presynaptic cell membrane {ECO:0000269|PubMed:15173594}; Multi-pass membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000269|PubMed:15173594}. Early endosome membrane {ECO:0000250|UniProtKB:Q9GZV3}; Multi-pass membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q9GZV3}; Multi-pass membrane protein {ECO:0000305}. Note=Localized to motor neuron axons. {ECO:0000269|PubMed:15173594}.
Interaction partners:
- Vesicular acetylcholine transporter
- Choline O-acetyltransferase
- Choline transporter-like protein 1
Sequence:
MSFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYSDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ
Protein: Transcriptional activator protein rep2 (Q09824)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Transcriptional activator which interacts with the mcb binding subunit complex formed by res2 and cdc10. Rep2 is required for the mitotic cell cycle start.
Interaction partners:
- Cell division cycle-related protein res2/pct1
- Cell division cycle-related protein res1/sct1
- Start control protein cdc10
- Transcription factor nrm1
- Transcriptional activator protein rec16
- MBF complex negative regulatory component yox1
Sequence:
MHFADIPLSKPCLNNPPTYPWSSPILSSIANPSLCDIVSSPSSVSSFASSDDFAFMNAYCLPIQQNHQFGSPVAASPNQQPLVESQNRRNVTYASLVIGKLGIAQLIRQQTDPPQIIHRKQDKGLMARVLSRSKKQEERENHSSDARDAIKSALRRRMRRREGRVQKALRPTPNLICSKCNTTFNHSTALMMHEATCLNQVPFKLSDFFVEDVIDDWLF
Protein: Coiled-coil domain-containing protein 90B, mitochondrial (Q8C3X2)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion membrane {ECO:0000250|UniProtKB:Q9GZT6}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein FAM32A
Sequence:
MRSRWIWRFLRPDGGGIRWTSTPHGRLSPALRRGFLTTTTKSDYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAQTIVSVLSTLSNVSLDTIYKEMVTKAQQEITVQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLTNETSRIRADNKLDINLERSRVTDMFTDQEKQLIEATNEFAKKDTQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGFYRFWKEN