wanglab/gogpt-training-data huggingface dataset:
Protein: GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Glycosylphosphatidylinositol-anchor biosynthesis protein 14) (P47088)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- GPI mannosyltransferase 2
- GPI mannosyltransferase 3
- Protein PBN1
- N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
- Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit
- GPI ethanolamine phosphate transferase 3
- GPI-anchored wall transfer protein 1
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI15
- Dolichol-phosphate mannosyltransferase
- Double-strand break repair protein MRE11
Sequence:
MTGEEWGLTVLSFLVRVGFFLFGIYQDANFKVRYTDIDYFVFHDAAKYVYEGKSPYARDTYRYTPLLSWLLVPNHYFGWFHLGKVIFVIFDLVTGLIIMKLLNQAISRKRALILESIWLLNPMVITISTRGNAESVLCCLIMFTLFFLQKSRYTLAGILYGLSIHFKIYPIIYCIPIAIFIYYNKRNQGPRTQLTSLLNIGLSTLTTLLGCGWAMYKIYGYEFLDQAYLYHLYRTDHRHNFSVWNMLLYLDSANKENGESNLSRYAFVPQLLLVLVTGCLEWWNPTFDNLLRVLFVQTFAFVTYNKVCTSQYFVWYLIFLPFYLSRTHIGWKKGLLMATLWVGTQGIWLSQGYYLEFEGKNVFYPGLFIASVLFFVTNVWLLGQFITDIKIPTQPTVSNKKNN
Protein: CBF1-interacting co-repressor CIR N-terminal domain-containing protein (Q386S4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MYASHKKDINRHKSFHPLTFQNLSRVERGLEKEEEKKKAKEQRNAELLHDQEQRRYDDLVISASGDSIAARVAKFRQVENVFAAEEDKPALQPEAVAVMGQKTSALTFQKDPLEAKKLTQKRQRDDVTTKNEKGGSEGQSFGGAGRKEEERKVSGSLVTGFITKSDAAQLRKELDKLQKERHDPLRRVEQFQNRTVAAEAKRRALEARAASNNSRGDLQKDIIHSRLQELLDMKK
Protein: Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor (HB-EGF) (HBEGF)] (Q06175)
Organism: Rattus norvegicus (Rat)
Function: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor (By similarity).
Subcellular location: [Heparin-binding EGF-like growth factor]: Secreted, extracellular space. Note=Mature HB-EGF is released into the extracellular space and probably binds to a receptor.; SUBCELLULAR LOCATION: [Proheparin-binding EGF-like growth factor]: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
- Receptor tyrosine-protein kinase erbB-4
- Receptor protein-tyrosine kinase
- Pro-epidermal growth factor
- Receptor tyrosine-protein kinase erbB-3
- Matrix metalloproteinase-9
- Pro-epidermal growth factor
- Glypican-1
- Proepiregulin
- Matrix metalloproteinase-17
- Matrix metalloproteinase-14
Sequence:
MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAATSNPDPPTGTTNQLLPTGADRAQEVQDLEGTDLDLFKVAFSSKPQALATPGKEKNGKKKRKGKGLGKKRDPCLKKYKDYCIHGECRYLKELRIPSCHCLPGYHGQRCHGLTLPVENPLYTYDHTTVLAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDLESEEKVKLGMASSH
Protein: Pyruvate carboxylase (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) (Q9UUE1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Malate dehydrogenase, mitochondrial
- Probable acetyl-coenzyme A synthetase
- Probable L-lactate dehydrogenase
- NAD-dependent malic enzyme
- Probable citrate synthase, mitochondrial
- Pyruvate kinase
- NAD-dependent malic enzyme
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
- Probable NAD-specific glutamate dehydrogenase
Sequence:
MTSKYDALLHNQSTNTNPFSKLQDRSSLLGEKFTKVLVANRSEIAIRVFRTAHELSMHTVAIYSYEDRLSMHRQKADESYPIGKVGQYSPVGAYLAIDEIVSIAKRTGANLVHPGYGFLSENAEFARKVNEAGMQFVGPSPEVIDSLGDKTKARAIAIRCGVPVVPGTPGPVEHYEEAEAFVKEYGLPVIIKAAMGGGGRGMRVVRSADTLKESFERARSEALASFGDGTVFIERFLDKPKHIEIQLMADKAGNVIHLHERDCSVQRRHQKVVEIAPAKDLDPKIRQALYDDAIKIAKEVKYCNAGTAEFLLDQKGRHYFIEINPRIQVEHTITEEITGVDIVSAQLHVAAGFTLPEIGLTQDKISTRGFAIQCRVTTEDPNNGFAPDIGKIEVYRSAGGNGVRLDGANGFAGSVITPHYDSMLVKCTCHDATYEYTRRKMIRSLIEFRVRGVKTNIPFVLRLLMHDTFIQGNCWTTFIDDTPELFQLYRSRNRAQKLLAYLGDLAVNGSSIKGQNGEPALKSEIVMPVLLDSTGNQIDVSHPSEKGWRKLLLDNGPAAFAKAVRNHKRGLIMDTTWRDAHQSLLATRVRTIDLVNIAPYTSHALASAYSLEMWGGATFDVSMRFLHECPWDRLRRLRKLVPNIPFQMLLRGANGLCYSSLPDNVIYFFCEQAKKNGIDIFRVFDALNDVNNLSLGIDAAKRAGGVVEATMCYSGDMLNPKKKYNLDYYVNLVDKMVEMGIHILGIKDMAGVMKPKAARLLISAIREKHPELPIHVHTHDSAGTAVASMAAALEAGADVVDVATDSMSGLTSQPSFGAVLASVDGTDKQLEFDNNQLREIDSYWAQMRLLYSPFESEIKGTDSDVYNHEIPGGQLTNLKFQATSLGLGTQWAETKKAYIEANKLLGDIIKVTPTSKVVGDLAQFMVQNKLSAEDVENRATTLDFPASVLDFFQGLMGQPYGGFPEPLRTNVLKGRRQPLTDRPGKFLPAADFDAIRKLLSEKFGVSSDCDIAAYTQFPGVFEEYRQFVDRYGDLTTVPTKFFLSRPEMNEEMHVEIDQGKTLIVKFVALGPLNPRTGQREVYFELNGENRHVTVEDKKAAIETVTRPRADPGNPGHVAAPMSGTIVEIRVKEGAKVKKGDIIAVLSAMKMEIVISAPHSGVLKSLAVVQGDSVNGGDLCAVLEHE
Protein: Protein FAR1-RELATED SEQUENCE 3 (Q9ZVC9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription activator involved in regulating light control of development.
Subcellular location: Nucleus {ECO:0000269|PubMed:15591448}. Note=The nuclear localization is independent of the light treatment.
Interaction partners:
- Zinc finger MYM-type-like protein
- Zinc finger MYM-type-like protein
- GATA transcription factor 28
- Histone acetyltransferase subunit NuA4-domain protein
- Putative cysteine-rich receptor-like protein kinase 32
- AT-hook motif nuclear-localized protein 14
- Zinc finger CCCH domain-containing protein 32
- Type IV inositol polyphosphate 5-phosphatase 9
- Protein mago nashi homolog
- Zinc finger CCCH domain-containing protein 48
Sequence:
MDVHLVEENVSMGNHEIGDEGDVEPSDCSGQNNMDNSLGVQDEIGIAEPCVGMEFNSEKEAKSFYDEYSRQLGFTSKLLPRTDGSVSVREFVCSSSSKRSKRRLSESCDAMVRIELQGHEKWVVTKFVKEHTHGLASSNMLHCLRPRRHFANSEKSSYQEGVNVPSGMMYVSMDANSRGARNASMATNTKRTIGRDAHNLLEYFKRMQAENPGFFYAVQLDEDNQMSNVFWADSRSRVAYTHFGDTVTLDTRYRCNQFRVPFAPFTGVNHHGQAILFGCALILDESDTSFIWLFKTFLTAMRDQPPVSLVTDQDRAIQIAAGQVFPGARHCINKWDVLREGQEKLAHVCLAYPSFQVELYNCINFTETIEEFESSWSSVIDKYDLGRHEWLNSLYNARAQWVPVYFRDSFFAAVFPSQGYSGSFFDGYVNQQTTLPMFFRLYERAMESWFEMEIEADLDTVNTPPVLKTPSPMENQAANLFTRKIFGKFQEELVETFAHTANRIEDDGTTSTFRVANFENDNKAYIVTFCYPEMRANCSCQMFEHSGILCRHVLTVFTVTNILTLPPHYILRRWTRNAKSMVELDEHVSENGHDSSIHRYNHLCREAIKYAEEGAITAEAYNIALGQLREGGKKVSVVRKRIGRAAPPSSHGGGIGSGDKTSLSAADTTPLLWPRQDEMIRRFNLNDGGARAQSVSDLNLPRMAPVSLHRDDTAPENMVALPCLKSLTWGMESKNTMPGGRVAVINLKLHDYRKFPSADMDVKFQLSSVTLEPMLRSMAYISEQLSSPANRVAVINLKLQDTETTTGESEVKFQVSRDTLGAMLRSMAYIREQLSIVGELQTESQAKKQRK
Protein: Nicotianamine synthase 1 (EC 2.5.1.43) (S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 1) (AtNAS1) (Q9FF79)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Synthesizes nicotianamine, a polyamine which serves as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.
Interaction partners:
- Ferric reduction oxidase 2
- Metal-nicotianamine transporter YSL2
- Protein DETOXIFICATION 43
- Metal-nicotianamine transporter YSL1
- Fe
- Metal transporter Nramp3
- Protein ZINC INDUCED FACILITATOR 1
- Ferric reduction oxidase 3, mitochondrial
- Transcription factor ORG2
- Ferric reduction oxidase 6
Sequence:
MACQNNLVVKQIIDLYDQISKLKSLKPSKNVDTLFGQLVSTCLPTDTNIDVTNMCEEVKDMRANLIKLCGEAEGYLEQHFSTILGSLQEDQNPLDHLHIFPYYSNYLKLGKLEFDLLSQHSSHVPTKIAFVGSGPMPLTSIVLAKFHLPNTTFHNFDIDSHANTLASNLVSRDPDLSKRMIFHTTDVLNATEGLDQYDVVFLAALVGMDKESKVKAIEHLEKHMAPGAVLMLRSAHALRAFLYPIVDSSDLKGFQLLTIYHPTDDVVNSVVIARKLGGPTTPGVNGTRGCMFMPCNCSKIHAIMNNRGKKNMIEEFSAIE
Protein: G-protein coupled receptor 161 (B2RPY5)
Organism: Mus musculus (Mouse)
Function: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown.
Subcellular location: Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Mainly localizes to primary cilium in a TULP3 and IFT-A complex-dependent manner. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes and is apparently not degraded.
Interaction partners:
- Beta-arrestin-2
- Beta-arrestin-1
- Guanine nucleotide-binding protein G
- Tubby-related protein 3
- ADP-ribosylation factor-like protein 13B
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- Intraflagellar transport protein 140 homolog
- Protein smoothened
- Tetratricopeptide repeat protein 21B
Sequence:
MDFVQHALLTASRGALTMSLNSSLSYRKELSNLTATEGGEGGAVSEFIAIIIITVLVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHQEPGYTIFWQIWCALFPFLIMLVCYGFIFRVARVKARKVHCGTVVTVEEDSQRSGRKNSSTSTSSSGSRRNALQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNCVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYRESFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQSLGHSSSTGDTGFSYSQDSGTDVMLLEDGTSEDNPPQHCTCPPKRRSSVTFEDEVEQIKEAAKNSLLHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLFTARTVPGAGFGGRRGSRTLVNQRLQLQSIKEGNVLAAEQR
Protein: Lipase E, hormone sensitive type (M0R2G1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MPRRASRLIHNMDLRTMTQSLVTLAEDNIAFFSSQGPGETAQRLSGVFAGVREQALGLEPALGRLLGVAHLFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGLSVAASSLFT
Protein: Growth hormone receptor (Q0R5U2)
Organism: Bos taurus (Bovine)
Interaction partners:
Sequence:
EGKLEEVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEKSLNIFGAKDDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDAAPASQQPSVILVEENKPRPLLIGGTESTHQAVHTQLSNPSSLANIDFYAQVSDITPAGNVVLSPGQKNKTGNPQCDTHPEVVTPCQANFIVDTAYFCEVDAKKYIALAPHVEAESHVEPGFNQEDIYITTESLTTTAGRSGTAEHVPSSEIPVPDYTSIHIVQSPQGLVLNATALP
Protein: Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] (Precorrin-6 methyltransferase) (Precorrin-6Y methylase) (EC 2.1.1.132) (P9WGA9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X.
Interaction partners:
- Precorrin-6A reductase
- Precorrin-8X methylmutase
- Precorrin-4 C
- Cobalamin biosynthesis protein CobIJ
- Cobalamin biosynthesis protein CobN
- Cobalamin biosynthesis protein CobD
- Probable cob
- Adenosylcobinamide kinase
- Uncharacterized oxidoreductase Rv2073c
- Precorrin-3B synthase CobG
Sequence:
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLLDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
Protein: Metal transporter Nramp2 (AtNramp2) (Q9C6B2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Seems to be involved in iron uptake.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Metal tolerance protein 11
- At5g23760
- Fe
- Calcium-transporting ATPase 3, endoplasmic reticulum-type
- Plastocyanin-like domain-containing protein
- Probable copper-transporting ATPase HMA5
- Protein NRT1/ PTR FAMILY 5.9
- Classical arabinogalactan protein 27
- Putative metal tolerance protein C3
- Protein PAM71, chloroplastic
Sequence:
MENDVKENLEEEEDRLLPPPPPSQSLPSTDSESEAAFETNEKILIVDFESPDDPTTGDTPPPFSWRKLWLFTGPGFLMSIAFLDPGNLEGDLQAGAIAGYSLLWLLMWATAMGLLIQMLSARVGVATGRHLAELCRDEYPTWARYVLWSMAELALIGADIQEVIGSAIAIQILSRGFLPLWAGVVITASDCFLFLFLENYGVRKLEAVFAVLIATMGLSFAWMFGETKPSGKELMIGILLPRLSSKTIRQAVGVVGCVIMPHNVFLHSALVQSRKIDPKRKSRVQEALNYYLIESSVALFISFMINLFVTTVFAKGFYGTEKANNIGLVNAGQYLQEKFGGGLLPILYIWGIGLLAAGQSSTITGTYAGQFIMGGFLNLRLKKWMRAVITRSCAIVPTMIVAIVFNTSEASLDVLNEWLNVLQSVQIPFALLPLLTLVSKEEIMGDFKIGPILQRIAWTVAALVMIINGYLLLDFFVSEVDGFLFGVTVCVWTTAYIAFIVYLISHSNFFPSPWSSSSIELPKRVSVSNS
Protein: Neuronal membrane glycoprotein M6-a (Q86YB0)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, dendritic spine {ECO:0000256|ARBA:ARBA00004552}. Cell projection, filopodium {ECO:0000256|ARBA:ARBA00004486}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGRCVSAWFIMLTYLFMLAWLGVTAFTSLPVYMYFNLWTICRNTTLVEGANLCLDLRQFGIVTIGEEKKICTVSENFLRMCESTELNMTFHLFIVALAGAGAAVIAMVHYIMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLNAYT
Protein: Ciliary microtubule inner protein 1 (Q9H1P6)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:25786037}.
Interaction partners:
- Sentan
- A-kinase anchor protein 14
- Cilia- and flagella-associated protein HOATZ
Sequence:
MAQKPLSTAAAERMNLVGQDEIWKYRLKAESEARQNWPQNWGFLTTPFEELIKCEEDLPTPKPKIELPERFRIRPVTPVEKYIKVFPSPPVPQTTQGFIGWRSAVPGLNKCLELDDAIRSCKGAFARELCWPKQGVH
Protein: DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (O14593)
Organism: Homo sapiens (Human)
Function: Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9Z205}. Nucleus {ECO:0000250|UniProtKB:Q9Z205}.
Interaction partners:
- DNA-binding protein RFX5
- Regulatory factor X-associated protein
- MHC class II transactivator
- DNA-binding protein RFX7
- Histone deacetylase 4
- MHC class II regulatory factor RFX1
- Cyclic AMP-responsive element-binding protein 1
- Nuclear transcription factor Y subunit gamma
- Nuclear transcription factor Y subunit alpha
- Myocyte-specific enhancer factor 2B
Sequence:
MELTQPAEDLIQTQQTPASELGDPEDPGEEAADGSDTVVLSLFPCTPEPVNPEPDASVSSPQAGSSLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELDQLKEHLRKGDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQSNLVPADPE
Protein: Activator protein 4 (Transcription factor AP4) (Q9JIZ5)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Cyclin-dependent kinase inhibitor 1
Sequence:
MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQHLRTQLLPPPAPTHHPTVIVPAPAPPSSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQDKQELEEEQRRAVIVKSVRSCPDAHTSDTASDSEASDSDAMDQSREEPLGDGELP
Protein: Large ribosomal subunit protein eL37A (Probable 60S ribosomal protein L37-A) (Ribosomal protein L37-1) (Q9VXX8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Binds to the 23S rRNA.
Interaction partners:
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein eS4
- Large ribosomal subunit protein eL20
- 40S ribosomal protein S24
- Small ribosomal subunit protein uS15
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein uL30
- Small ribosomal subunit protein eS8
- Small ribosomal subunit protein uS9
Sequence:
MTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKSTCAQCGYPAAKLRSYNWSVKAKRRKTTGTGRMQHLKVVRRRFRNGFREGTQAKPKKAVASK
Protein: Phosphoglycerate kinase (EC 2.7.2.3) (Q4QD34)
Organism: Leishmania major
Interaction partners:
- Triosephosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Glyceraldehyde-3-phosphate dehydrogenase
- Glyceraldehyde-3-phosphate dehydrogenase-like protein
- phosphoglycerate mutase
- Phosphoglycerate kinase
- Phosphoglycerate kinase
- Putative phosphoglycerate mutase protein
- ATP-dependent 6-phosphofructokinase
- Transketolase
Sequence:
MSLVLKKSIDDATVRDKKVLIRVDFNVPVKNGKITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKGARMSDPSPEKGVRGYEEAATLRPVAARIAELLGQKVEFAPDCLDAAAYASKLKNGDVLLLENVRFYAEEGSKKEEERDAMAKVLASYADLYVSDAFGTAHRDSATMTGIPKVLGAGYAGYLMEKEINYFSRVLNNPPRPLVAIVGGAKVSDKIELLDNMLSRINYLVIGGAMAYTFQKAQGRKIGISMCEEDKLDLAKSLLKKAQERGVQVFLPVDHVCNKEFKAADSPLVTESVDVPDGYMALDIGPRTIHMYEEVIGRCKSAIWNGPMGVFEMPCYSKGTFAVAKAMGTGTQKNGLLSIIGGGDSASAAELSGEAKNMSHVSTGGGASLELLEGKTLPGVAILTDKDVKERGASCRFAFGVGSPSREACPLRCGHIFGGASIVREIVKLVVALLIGIFIGRRMSTKLIR
Protein: Contact site A protein (CSA) (Cell adhesion molecule gp80) (Membrane-associated glycoprotein gp80) (P08796)
Organism: Dictyostelium discoideum (Social amoeba)
Function: This cell-surface glycoprotein mediates cell-cell binding via homophilic interaction.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the membrane by a GPI-anchor that contains a phosphoceramide moiety. Such anchor mediates a fast and long persistence cell adhesion of the protein.
Interaction partners:
- Tiger protein C1
- Adenylate cyclase, aggregation specific
- Calcium-dependent cell adhesion molecule 1
Sequence:
MKFLLVLIILYNILNSAHSAPTITAVSNGKFGVPTYITITGTGFTGTPVVTIGGQTCDPVIVANTASLQCQFSAQLAPGNSNFDVIVKVGGVPSTGGNGLFKYTPPTLSTIFPNNGRIGMILVDGPSNISGYKLNVNDSINSAMLSVTADSVSPTIYFLVPNTIAGGLLNLELIQPFGFSTIVTSKSVFSPTITSITPLAFDLTPTNVTVTGKYFGTTASVTMGSHIYTGLTVQDDGTNCHVIFTTRSVYESSNTITAKASTGVDMIYLDNQGNQQPITFTYNPPTITSTKQVNDSVEISTTNTGTDFTQISLTMGTSSPTNLVITGTNEKIVITLPHALPEGEIQFNLKAGISNVVTSTLLVTPVINSVTQAPHNGGSITISGIFLNNAHVSIVVDQNTTDIVCAPDSNGESIICPVEAGSGTINLVVTNYKNFASDPTIKTEATTSTTYTIPDTPTPTDTATPSPTPTETATPSPTPKPTSTPEETEAPSSATTLISPLSLIVIFISFVLLI
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A0A060YH61)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- AMP-activated protein kinase glycogen-binding domain-containing protein
- 5'-AMP-activated protein kinase subunit beta-1
- CBS domain-containing protein
- CBS domain-containing protein
- Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
- Association with the SNF1 complex
- Association with the SNF1 complex
- 5'-AMP-activated protein kinase subunit gamma-1
- 5'-AMP-activated protein kinase subunit gamma-1
- calcium/calmodulin-dependent protein kinase
Sequence:
VEDKEARRLFQQIISGVDYCHRHMVVHRDLKPENVLLDHSKNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYMPEYLTRPVASLLLLMLQVDPLKRATIKDIREHEWFKQDLPGYLFPEDPSYDSTILDEEAVREVCDKFESTESEVMSSLYSGDPQDQLAVAYHLIIDNRRIMTQASEFYLASSPPQGSFMEDGMSLPPGVKPHPERMPPLLVDSPKAMIFTWFYSMYYVHSIYNRIQDL
Protein: ATP synthase protein 8 (A6L) (F-ATPase subunit 8) (P0CY41)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
Subcellular location: Mitochondrion membrane; Single-pass membrane protein.
Interaction partners:
- ATP synthase subunit a
- Mitochondrial F1F0 ATP synthase subunit Atp18, putative
- ATP synthase subunit d
- ATP synthase subunit beta
- F1F0 ATP synthase assembly protein Atp10, putative
- ATP synthase subunit 4
- ATP synthase subunit alpha
- ATP synthase subunit alpha
- ATP synthase subunit 9, mitochondrial
- ATP synthase subunit 9
Sequence:
MPQLVPFFFVNQVVFAFIVLTVLIYAFSKYILPRLLRTYISRIYINKL
Protein: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (EC 1.14.11.4) (Lysyl hydroxylase 2) (LH2) (O00469)
Organism: Homo sapiens (Human)
Function: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Subcellular location: Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Interaction partners:
- Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
- Procollagen galactosyltransferase 2
- Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
- Procollagen galactosyltransferase 1
- Peptidyl-prolyl cis-trans isomerase FKBP10
- Calmodulin-lysine N-methyltransferase
- Prolyl 4-hydroxylase subunit alpha-1
- Prolyl 4-hydroxylase subunit alpha-2
- Collagen alpha-1
- Collagen alpha-1
Sequence:
MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP
Protein: Mitochondrial carrier protein, putative (Q382A1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAQSTARHVMNTPQSQQGQNLTPAETDNKPRQKSPSSHILASQLASAVSTTMFYPMDTLRIRYMSQDGTIQRQHNGQTYRSIYRAVGVIWKEEGLRALFRGCHVAVLGAVVAWGVYMFVYHALCDLYIPTSNKRAGDDFLFRTVLSSIASCSCAVVGNPIWLLKTRMQIEEIASREAAVAGASIFRNSKNYTSFFGGLRYAIQTDGVLSLWRGVSAQVLLGLPNALNFPAYEALKSFWLQRTDRETLYSYEACICSTASKTAVSIIGYPLHVVKTRMQDQRSRRGDLQYVSFLQSAWLVLQTHGFAGLYRGMVPSLLHSVPRLALTFVLYEKLMQQNFF