wanglab/gogpt-training-data huggingface dataset:
Protein: Transcription factor castor (Protein ming) (Q7M3M8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor that specifies expression of key genes in developing central nervous system (CNS). Essential for many, if not all, late developing neuroblastoma (NB) sublineages. Binds to the 5'-[CG]C[CT][CT]AAAAA[AT]-3' DNA sequence, like hb, suggesting that cas and hb act as a late regulators in early and late CNS NB sublineage, respectively. Acts by repressing expression of nub/pdm-1 and pdm2/pdm-2 POU genes, and restrict their pattern of expression in appropriate cells. Required for a full expression of vvl/drifter and acj6/I-POU; it is however unknown whether it directly activates these genes. Controls engrailed (en) expression in the ventral nerve chord.
Subcellular location: Nucleus {ECO:0000269|PubMed:9436984}.
Interaction partners:
Sequence:
MSNQMEFIMQLYMMNLMKQQQQMQLQLPQQQQQQQLAGYTYTQNEDISSSTSVQQQQQQQQEQLQQPQPDLRKTRTHKRISSQNTNCSSSRSCSPNSNLIAFQPQQYPGATAATPSTPNSHPSNLVNQMLLQSLPPLTQLMLQQQQQQHLLTTSNLLLTPTHTPSSLGKQDPLQHPLLLGQFAGSEQMATNNFLQSSTVTSTPIEREKAATPAPSAGATAGNLSAAQVKFEQESADDDEDDDKPLSSLTSCSSSGHTNASSEKLLLSGVHPLESTTDSLDSPSMYTPVKQPADSSYGLITPVDSDLTPNTPLQPTQTISLLTPPSSEQSKSLVSLSAASGLDALLQNEEVLKNLRKVSSYLECENSLCRQENLREHFHCHEEPCQGKILSKKDDIIRHLKWHKKRKESLKLGFARFSSSDDCAPAYGEGCAYNWKQTHYHCVYEHCPKVYVSTSDVQMHANFHRKDSEIVNEGFRRFRAHETCRIEDCPFFGKKISHYHCCREGCTHTFKNKADMDKHKTYHLKDHQLKMDGFKKILKTEVCPFDACKFSTVCNHIHCVREGCDYILHSSSQMISHKRKHDRQDGEQAYQQFKIKQDVEESSLDAMPQQQQQQQQQQPTSLSQSQSSSSVCGGSNTSTPLSSLSAEHFLARKRGRPPKKIQLPADAQQSEAKRLKVEDESSNPAMLLPQSQPAAAVHPLTSGLFPGLLPAAAAPGVDPTAPNFQLTHLMALFQLQNPLFYQNLYPGMTQNSSMLGNLAALSAASAAAAAAAAANGAGVQQPKAEFSFKPEFKE
Protein: Transcription factor Gibbin (AT-hook DNA-binding motif-containing protein 1) (Q6PAL7)
Organism: Mus musculus (Mouse)
Function: Transcription factor required for the proper patterning of the epidermis, which plays a key role in early epithelial morphogenesis. Directly binds promoter and enhancer regions and acts by maintaining local enhancer-promoter chromatin architecture (By similarity). Interacts with many sequence-specific zinc-finger transcription factors and methyl-CpG-binding proteins to regulate the expression of mesoderm genes that wire surface ectoderm stratification (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q5TGY3}. Chromosome {ECO:0000250|UniProtKB:Q5TGY3}. Note=Associates with promoter and enhancer regions. {ECO:0000250|UniProtKB:Q5TGY3}.
Interaction partners:
Sequence:
MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHTFSENPRPPPRRDPSSRRPPVLAKGDDLLPPRAARPVSQAHCPSPAPDNSSLRHWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERANPHTKSERPSHPLYEPEPEPRDSPQPGQGHGPGAAATATGLPPEPEPDGPDYSELADADILSELASLTCPEAQLLEAQALEPPSPQPEPQLLDPQPRFLDPQALEPLGEGLELPPLQPLADPLGLPSLTLQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQSLGHCQLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADSGPEGRLLPLPMPTGLAAALAEPPPLPPPPPPTLSGPGPVPELEPESSQTPMVPTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSSEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPTVVAAEAATVTAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISQFLHRVQGFRRRGGKTGGFGGRGGGHAAKAARCSFSDFFEGIGKKKKVVAVAAPGLVGPGLTELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWVGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYAGAPSGQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPSSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLPSRQTFPPGRATSYGITPATSDCRAAETFPKLAPPPSAVARSPTTHPPANTYPPQYGGYGAGQSVFASAKPFSGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFNSSEGGPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASAASVASSSSSSFQPSPENCRQFVGASQWPFRQGYGGLDWASEAFSQLYNPNFDCHGSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQFSQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFSTSTSATASGYPSKRSTGPRQPRGGRGSGACSAKKERGGTAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFMGPYSMNPSTPSDGTFGQGFHCDSPSLGAAELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPSKLTACEPLKHGLQGASLSHAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGSGLLADFLGRTEAVCLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAATAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL
Protein: Fanconi anemia group C protein (Protein FACC) (Q00597)
Organism: Homo sapiens (Human)
Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
Subcellular location: Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Interaction partners:
- Fanconi anemia group I protein
- E3 ubiquitin-protein ligase FANCL
- Fanconi anemia group E protein
- Centromere protein X
- Centromere protein S
- FA core complex associated protein 20
- Fanconi anemia group F protein
- Fanconi anemia group D2 protein
- Fanconi anemia group A protein
- Fanconi anemia core complex-associated protein 100
Sequence:
MAQDSVDLSCDYQFWMQKLSVWDQASTLETQQDTCLHVAQFQEFLRKMYEALKEMDSNTVIERFPTIGQLLAKACWNPFILAYDESQKILIWCLCCLINKEPQNSGQSKLNSWIQGVLSHILSALRFDKEVALFTQGLGYAPIDYYPGLLKNMVLSLASELRENHLNGFNTQRRMAPERVASLSRVCVPLITLTDVDPLVEALLICHGREPQEILQPEFFEAVNEAILLKKISLPMSAVVCLWLRHLPSLEKAMLHLFEKLISSERNCLRRIECFIKDSSLPQAACHPAIFRVVDEMFRCALLETDGALEIIATIQVFTQCFVEALEKASKQLRFALKTYFPYTSPSLAMVLLQDPQDIPRGHWLQTLKHISELLREAVEDQTHGSCGGPFESWFLFIHFGGWAEMVAEQLLMSAAEPPTALLWLLAFYYGPRDGRQQRAQTMVQVKAVLGHLLAMSRSSSLSAQDLQTVAGQGTDTDLRAPAQQLIRHLLLNFLLWAPGGHTIAWDVITLMAHTAEITHEIIGFLDQTLYRWNRLGIESPRSEKLARELLKELRTQV
Protein: Goa1p (Q5A672)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Nuo1p
- NADH-ubiquinone oxidoreductase subunit NUO2
- NADH dehydrogenase flavoprotein 1, mitochondrial
- SAM complex subunit
Sequence:
MLRSQLPCIQKRTLFQKYSNPPRLSYVANKSYISLIWNNLIPQPLKLTCLVASGIVTFVNVHPRYYITLGPPVGLLGFFGYQKYRHWQYHKAVSKLDVTKWQDNEIIRIAKYDEKSLDNVIMGIDNQYDSLRRQIIQLSEQRIIEYISEHGVEDEITRSFISDDNQFNVHLPELEIESWVTTNVKLEKNNDTVSEFIMLSVPYYDSKNVHTRKRLGVVSIYLLQIPQQEYSSFIDYKIGIEVTRLRWINPQSLFFTKLESKALMQSDIYKSLNKENQN
Protein: Chorion protein a at 7F, isoform A (LP18486p) (Q5BI73)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein
- GEO10373p1
- Chorion protein c at 7F
- Chorion protein b at 7F, isoform A
- Chorion protein S36
- Chorion protein S19
- MIP13722p
- Chorion protein S38
- Chorion protein S16
- Uncharacterized protein
Sequence:
MLACKLLLALVMGMHCIQLLMAACVCSEKGTDYCQSCQGSTVIRPKPRYYEPSDVNLPPIGDNCWCSKQLIEPAQLPKTCGKTTPCKPTCSCQQISSDSSYASSSSSGSVYGKIDYAAEKIVDNSPAADPISVSLAAQAGKAINVPEAKLAYGFAQKPVDGEKKVVFSNVPEENLFKLKSDVITLKKRTYATKQEDEEEYAEEEQEQEQSSDDEEAPQLTYKQLGYITEQYKNPKFRKISSSSSSYAYKDYKDSSESGYGKVAGKVSVDCGFKPGRITSYRKSKREESDDGYY
Protein: Proteasome subunit alpha type (H0YL69)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU000551}. Nucleus {ECO:0000256|RuleBase:RU000551}.
Interaction partners:
Sequence:
MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQL
Protein: Photosystem I reaction center subunit VI-1, chloroplastic (PSI-H1) (Q9SUI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Possible role could be the docking of the LHC I antenna complex to the core complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Photosystem I reaction center subunit XI, chloroplastic
- Photosystem I reaction center subunit III, chloroplastic
- Photosystem I reaction center subunit V, chloroplastic
- Photosystem I subunit O
- Photosystem I reaction center subunit psaK, chloroplastic
- Photosystem I reaction center subunit IV A, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 3-1, chloroplastic
- Photosystem I reaction center subunit II-1, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 2, chloroplastic
- Photosystem I reaction center subunit II-2, chloroplastic
Sequence:
MASLATVAAVKPSAAIKGLGGSSLAGAKLSIKPSRLSFKPKSIRANGVVAKYGDKSVYFDLEDLGNTTGQWDVYGSDAPSPYNPLQSKFFETFAAPFTKRGLLLKFLILGGGSLLTYVSATSTGEVLPIKRGPQEPPKLGPRGKL
Protein: Glycerol uptake operon antiterminator regulatory protein (P30300)
Organism: Bacillus subtilis (strain 168)
Function: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon.
Interaction partners:
- Uncharacterized aminotransferase YhxA
- Aerobic glycerol-3-phosphate dehydrogenase
- Glycerol uptake facilitator protein
- Glycerol kinase
Sequence:
MMSFHNQPILPAIRNMKQFDEFLNSSFSYGVILDIHLGQLKGVIKEAQKHGKNMMVHVDLIQGIKHDEYGAEFICQDIKPAGIISTRSNVIAKAKQKKIYAIQRLFLLDTSAMEKSMEFIGKHKPDFIEVLPGIVPSLIQEIKEKTGIPIFAGGFIRTEEDVEQALKAGAVAVTTSNTKLWKKYENFLTESD
Protein: Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (F4JLJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Neutral ceramidase 3
- Neutral ceramidase 2
- Neutral ceramidase 1
- Ceramide kinase
- beta-galactosidase
- Beta-galactosidase 2
- Sphingolipid delta
- Beta-galactosidase 17
- AP-2 complex subunit sigma
- AP3-complex subunit beta-A
Sequence:
MEKNGHTESELQTQMVGNERLPQVTWQRKLNSKVKNPSEFKMSIRDVLHLFPLGYRLWRYTKEEAKKGRFSMYDIFKKRHVRGDHGVPLGGIGGGSIGRSYKGEFQQFKLFPKICEEAPILTNQFSVFVSRPGGLSYSTVLCPTKPKSVKGKTEDLGIESWDWNMEGDKSTYHALYPRSWTVYNEPDPELRIVSRQVSPFIPHNYKESSLPVSVFEFTMSNLGKEEATVTLLFTWENSVGGASGLTGEHFNSTIMERDGVHAIVLHHKTGNGHPPVTYAIAAQETEDVHVSECPCFLVSGHSPKEITAKEMWDEIKKNKSFDELNSEPGSPSRPGTSIGAAIAAKVKVPPGCDRTVTFSLSWDCPEVRFNEKTYHRRYTKFYGNLGDAAVKMARDALLNYVDWESQIEAWQSPILSDTTLPDWYRVTLFNELYYFNSGGTIWTDGLPPKESIERSKVTNTEQNDIVIDLFQKINAVCEQIYSPQSSNSEENIGQFIYLEGIEYLMYNTYDVHFYSSFALLSLFPKLALSIQRDFAATVLIQDPTKKKIMSSGEWVTRKLLGSVPHDIGLNDPWLELNEYNFFNTDRWKDLNAKFVLQVYRDVVATNDQSFAKAVWPSVYTAVAYLDQFDKDEDGMIENEGFPDQTYDAWSVTGVSAYCGGLWVAALQAASAFASIVGENAVAIYFNAKYEKAKIVYEKLWNGSYFNYDDSGSGSSSSILADQLAGQWYARACGLKPITKEEWIKKALETIYEFNVMKVKGGTRGAVNGMSTEGKVDTNSLVSKEVWAGTTYSVAACMIQEGQREKGFQTASGIYEAIWSDRGLSCSFQTPEAWNMNDEYRSLCYMRPLAIWAIQWALTRTQSFGEEKQKLVAGDEEEESNLLLRQHKGFKDVARFVKIVPTSNVHRSRLQHTYETVLKTLRL
Protein: Peptide deformylase (EC 3.5.1.88) (Q381Y5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 60S ribosomal protein L17, putative
- 50S ribosomal protein L17, putative
- Large ribosomal subunit protein bL21m
- 40S ribosomal protein S13, putative
- 40S ribosomal protein S18, putative
- 40S ribosomal protein S15, putative
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S23, putative
- Large ribosomal subunit protein uL5
Sequence:
MLRHLFRCTAAWAPKRSATREQRLKERVAARMELEAQVKSRVACYPHRSLTRPALRLERHQVNTPLFHSQLLNLNKMATDLQCISFSAPKGHWDAAIVLIKGHPNEANFEVWVNPTVPGYDDRHSIAPMYGMWENCISCGACTAWVIRPQSITCSGLDEYGNEKTEVLDGMRARCLMHELDHLSGRTILDQAQGPEFIVSGIAMGQRDLWPPNFPSAEAYMTSPHQFFDYVKNGPIIPPGMEWFYAQSMNQQFEDARLSH
Protein: Protein MAO HUZI 4, chloroplastic (Q5ZEG0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Required for neoxanthin biosynthesis, an intermediary step in abscisic acid (ABA) biosynthesis. Involved in an ABA pathway that acts at or downstream of ethylene receptors and positively regulates root ethylene response. In coleoptiles the MHZ4-dependent ABA pathway acts at or upstream of EIN2 to negatively regulate coleoptile ethylene response.
Subcellular location: Plastid, chloroplast envelope {ECO:0000305|PubMed:25330236}. Plastid, chloroplast membrane {ECO:0000305|PubMed:25330236}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MAALLLLSSAARVGVAAPLALRQQRPVVLPGGQLRTGSGAGAASAWAARPLRPELAAVSRPAVPARGRAPLFRPRAWMASSQIASSAFTWGTIAVLPFYTLMVVAPNADVTKRAVDSSAPYVALGILYAYLLYLSWTPDTLRAMFASKYWLPELTGIVRMFASEMTVASAWIHLLAVDLFAARQVYHDGIKNNIETRHSVSLCLLFCPIGIATHVLTKVLAGSIGRSH
Protein: NADH-cytochrome b5 reductase 2 (b5R.2) (EC 1.6.2.2) (Q3KNK3)
Organism: Mus musculus (Mouse)
Function: NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1) (By similarity).
Interaction partners:
- Sulfite oxidase, mitochondrial
- Dihydroorotate dehydrogenase
- Dihydropyrimidine dehydrogenase [NADP
- Uridine 5'-monophosphate synthase
Sequence:
MSVKKKDLITLQDPEAKYPLPLIEKEQISHNTRRFRFGLPSPDHVLGLPVGNYVHLLAQINNELVIRAYTPVSSDDDQGFVDLIIKIYFKNVHPKYPEGGKMTQYLENMKIGDTILFRGPTGRLFYNEPGTLLIKANKTSEPEKKLVHHLGMIAGGTGITPMLQLIRHITKDTSDETRMSLLFANQTEEDILLRKELEEVATTHHKQFNLWYTLDRPPSDWKYSSGFVSADMIKEHLPPPGEDTLILVCGPPPLIQAAAHPSLEQLSYTKDMIFIY
Protein: Erythropoietin (Erythropoietin-L2) (Q2XNF5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
Subcellular location: Secreted {ECO:0000269|PubMed:17706649}.
Interaction partners:
- Erythropoietin receptor.
- Erythropoietin b.
- Thrombopoietin.
- GATA-binding protein 1a.
- Transferrin receptor 1b.
- Tyrosine-protein kinase.
Sequence:
MFHGSGLFALLLMVLEWTRPGLSSPLRPICDLRVLDHFIKEAWDAEAAMRTCKDDCSIATNVTVPLTRVDFEVWEAMNIEEQAQEVQSGLHMLNEAIGSLQISNQTEVLQSHIDASIRNIASIRQVLRSLSIPEYVPPTSSGEDKETQKISSISELFQVHVNFLRGKARLLLANAPVCRQGVS
Protein: Serine/threonine-protein phosphatase PP1(4.8) (EC 3.1.3.16) (P23733)
Organism: Trypanosoma brucei brucei
Interaction partners:
Sequence:
MNCDEIIKKLLLNPVHNTAATRGPAGENCESNQRTYTRISRLAAFQSAQTQESTPKTNGTGRATTEGLTEAEVRWLVMESRALFMSQPMLVEIAAPVRICGDVHGQYTDLLRLFDLGGFPPDANYIFLGDYVDRGDQSLERICLLLAYKLSFPETFFLLRGNHECSSINRIYGFFDECKRRYSVRLWKQFTDTFNCMPVAGLVEGRILCMHGGLSPELTDLDQIRRILRPTDVPDSGLICDLLWSDPSTNMESNWSENDRGVSWTFSESVVKSFNKKFDLDLICRAHQVVDAGYEFFAARQLVTVFSAPNYCDEFDNAGAFMCVDENFMCSFIRIEPTRTLLKYFF
Protein: Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4 (EC 3.6.4.13) (Masculinization of germline protein 4) (Sex determination protein mog-4) (O45244)
Organism: Caenorhabditis elegans
Function: ATP-binding RNA helicase involved in pre-mRNA splicing (Probable). Operates during embryogenesis.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Pre-mRNA-splicing factor SYF1
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- Cell division cycle 5-like protein
- Pre-mRNA-splicing factor 8 homolog
- PSP proline-rich domain-containing protein
- G-patch domain and KOW motifs-containing protein homolog 1
- Pre-mRNA-processing factor 17
- Splicing factor 3B subunit 3
- Matrin-type domain-containing protein
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1
Sequence:
MSVEQFINDQLHSIVGISDRSICQYVHALAKKAKSAPDLVEKLRDAGDFPISPAIQSFADQLMSRMPRQATSARQRGPTTAELAEQELNRLNRAVGVLEDYSASSTKTKNVRKRKESSSEDDEAPIKASKPGKSVKPSKSDDSESDIEAMEAKLDADIAERDALAARINKKEKDKTRNVMEKKRDDNKDKEGSSMDKLREESRRQYLKKRKVDKLEELEAIVHDDQTLFAREKLTKREKADMEYRKKVLEYTKAHGKAGDVMKMKRYHLPDASTKQIPSQYVEDDEEDFRPGGDGAKWEEEQLMASMLHLGAKDAKRKEQEFELLLDEKVDFIQALQMPGTNEEVVETEAEKKKMSIEETRKSLPVYAFRDAFIEAVKEHQVLIIEGETGSGKTTQLPQYLYEAGFCEGGKRIGCTQPRRVAAMSVAARVADEVGCKLGTQVGYSIRFEDCTSEKTVLKYMTDGMLLREFLNEPDLASYSVMMIDEAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAEKFSSFFDDAPIFRIPGRRFPVDIYYTQAPEADYVDAAIVTIMQIHLTQPLPGDILVFLTGQEEIETVQEALMERSKALGSKIKELIPLPVYANLPSDLQAKIFEPTPKDARKVVLATNIAETSVTIDGINYVIDPGFSKQNSFDARSGVEHLHVVTISKAAANQRAGRAGRTGPGKCFRLYTAWAYKHELEEQPIPEIQRTNLGNVVLMLKSLGIHDLVHFDFLDPPPQETLVIALEQLYALGALNHRGELTKLGRRMAEFPCDPCMSKMIIASEKYECSEEIVTIAAMLSCNAAVFYRPKAQVIHADSARKGFWSPAGDHITLMNVYNKWQESSFSQRWCVENYVQHRTMKRARDVRDQLVGLLERVEIETKSSTDTIKIRKAITAGYFYNVSKLDNTGHYKTVKHKHTTHPHPNSCLFEETPRWVVYFELVFTSKEFMREMSEIESGWLLEVAPHYYKGRELEDATNKKMPKNKGKSGKDLER
Protein: Lysine demethylase 4C (A0A1W2Q651)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
ALSSLSFGWRLDLLQRRRYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDK
Protein: EF-hand domain-containing protein (Q382W6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Paraflagellar rod component
Sequence:
MAFLVQVAADIFNNKVNFELSFPSRPSISELTRSAETAFSNEISLRRPDNVPSHKFHSSKIKMYDEELNKWVDLIREDQLTDYCQLYVFQPPNEWHKESQKEIPPAMKPPSSGQRHSAGGSFSQGSRVTPNGSLSMQGALAPYNGSRSPVSHRSESQQARHASFHGSTSNALVPRAQTDVSQEEKLRVLFAELDVKGNRVLDVEDFRHGFTVFNLNFSPATVDDLFEKGDSNRDGRITFSEFERFGRLYPIMTDCLYFRSRAFWEEEQIRRSIQNERQAVRQAEQAVEQARRALEEAENETDAAKDAVATADADLKDRTDRLRDLTRDMDNAKREKERAIREKKDREKELFEIREREKELRKDAQEVAREAEKQDRRAFSLAGEASAADDKVRALEKALDEARRAAERAHNAADQAARDADIVKLRMQDATRDAEEVAREVPRAEDAVRAAEHNVSAADQGARELEGMGRVLSREIEEAGQRRDQSEKAVEEARGMMHVKERQLEEAKQHVSEREHAVRLKEIELADQLKQRELVSQHERTLIEQELRLREQRDSLEERETKLMSEASSFLGNLRTQLHGGRSYPRD
Protein: Pentatricopeptide repeat-containing protein At1g71210, mitochondrial (Q8GZA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000305|PubMed:25732537}.
Interaction partners:
- Alpha-L-fucosidase 2
- DNA-directed RNA polymerase III subunit 2
- Putative disease resistance protein At4g19050
- Probable inorganic phosphate transporter 1-5
Sequence:
MLRCWSVTVERSCEGMLLRRRILSLSASSFRNFTSGNNGDAIPFSTFTKPSSSIAPGDFLVREWKDWFKHRDVKQSHQLIDRIFDILRAPSNDGDDRAFYLHLSNLRLRLTEKFVLDVLSHTRYDILCCLKFFDWAARQPGFHHTRATFHAIFKILRGAKLVTLMIDFLDRSVGFESCRHSLRLCDALVVGYAVAGRTDIALQHFGNMRFRGLDLDSFGYHVLLNALVEEKCFDSFDVIFDQISVRGFVCAVTHSILVKKFCKQGKLDEAEDYLRALLPNDPAGCGSGLGILVDALCSKRKFQEATKLLDEIKLVGTVNMDRAYNIWIRALIKAGFLNNPADFLQKISPLEGCELEVFRYNSMVFQLLKENNLDGVYDILTEMMVRGVSPNKKTMNAALCFFCKAGFVDEALELYRSRSEIGFAPTAMSYNYLIHTLCANESVEQAYDVLKGAIDRGHFLGGKTFSTLTNALCWKGKPDMARELVIAAAERDLLPKRIAGCKIISALCDVGKVEDALMINELFNKSGVDTSFKMFTSLIYGSITLMRGDIAAKLIIRMQEKGYTPTRSLYRNVIQCVCEMESGEKNFFTTLLKFQLSLWEHKVQAYNLFIEGAGFAGKPKLARLVYDMMDRDGITPTVASNILMLQSYLKNEKIADALHFFHDLREQGKTKKRLYQVMIVGLCKANKLDDAMHFLEEMKGEGLQPSIECYEVNIQKLCNEEKYDEAVGLVNEFRKSGRRITAFIGNVLLHNAMKSKGVYEAWTRMRNIEDKIPEMKSLGELIGLFSGRIDMEVELKRLDEVIEKCYPLDMYTYNMLLRMIVMNQAEDAYEMVERIARRGYVPNERTDMILERANRILEERNSRSNLGRNGWNSRQRQLE
Protein: NADPH:adrenodoxin oxidoreductase, mitochondrial (EC 1.18.1.6) (A0A0A0MSZ4)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|PIRNR:PIRNR000362}.
Interaction partners:
Sequence:
MASRCWRWWGWSAWPRTRLPPAGSTPTFGGSDEVRDPANAKALRNKRRRMQVRVKLGKFQLLLDIQEKTPQICVVGSGPAGFYTAQHLLKHPQAHVDIYEKQPVPFGLVRFGVAPDHPEVKNVINTFTQTAHSGRCAFWGNVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLPENQELEPDLSCDTAVILGQGNVALDVARILLTPPEHLERTDITKAALGVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQLPGARPILDPVDFLGLQDKIKEVPRPRKRLTELLLRTATEKPGPAEAARQASASRAWGLRFFRSPQQVLPSPDGRRAAGVRLAVTRLEGVDEATRAVPTGDMEDLPCGLVLSSIGYKSRPVDPSVPFDSKLGVIPNVEGRVMDVPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDLKAGLLPSGPRPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLRLLGH
Protein: Spinophilin, isoform I (M9NDX8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MEKPMHHAPAPVGKVSQIANIFQRKPIEIQPVEQLSAVAAAHAAAAAAAAAAHHAHVQGAPAVRTESHSARFNNARALFEKLGVESNSNVSSRLLRSGSREDNLCDGSDRSSSRSSDRSQSPPKRRTPFPSGVSLVHNNNNAAIVAQNGVPPEQRLSNSKFIVEPAAQVVPTSVVKYPQHNISRLKSEEPSPVPPPASGSVSALFASSGGDKPEKPERKFNSRELIEKQKKWTSHFTKTKTTRTHSDLNRCDIIRTVPGTGLIMDSEKVAKPAMEPPQPPPNASPNPPMRAQAPPEIKPRSGKIGSPVKSPPLPPIPAVKPKNVSPVKFNPDRLRQSPTKTADNSPPPPPAKSAAVLQRSLMQEQQELLRNSCDQGVAPIPPEKPRKKSVDLIEDTLPLTNCSTPSSCASPTSSYLMQPAKRGSLDGGSGNGQYPGNGLSGSTNSATSGSPVASASSGPSSPVHTEDEKQENESTEKSEMEYYHGGNYNSVPRRRRSENEGRKSVDESSPSANNSQQQQQHSIPGSAAGSPQRVANKRSSITVNMPAAGLGQRPPSIISTTSQDEGGFNESAPELKAKLQPAYDQTEEQPHSLNYVDVGYRLNPDGSESREVYGSEAELYDTAKVTDMQRKFHGANGFGQESSTVYAIIKPDVQESQPVAPSRSVLIQSPNSSSVEGSPLHRGSYSSPPVGVVSPIRRRNSSNQDQSVGGGGSAKTTPQCSPARSALVKGIAPIASIDAHEEEELDLVEEDEHLAVEYVEVLELQQDEEEEEAPVLPERRAPAQGSLELQDLEYADTSAGEDEEDIINHLKDGDVLDVELIDDVVDEVIKVHVNHSVATAPSIQAATPAAAIPREDSLPDDMTAAEAERLLSSSILENKIRQQSLLSDEQAKEVEQILNAAPSVGVAVATVVATATSPTSIKNLIEDLPGQSAVAASAANGEQDIQIAAVPAIVEEDEDEEEDFPEDDEEDHARADFDANGGDADGDSDDVEAVDIVGYGHASTALNATFVKADSTETETTTTTPSTATTATTRHDDDEPEWLRDVLEAPKRSLENLLITSATSSRAPGQREELENGYDLHEKHSDLNQTYITGGESLHESIVSVESTQSDATLNQTTTIDDSIISSKHNSTYSLADAEQATSSTVLSTGVTELDDSQYYIPEYPPVRSKEVLVEAGVHYFEDGNFWMEVPGLLDFDDDDCSYPPITVRKNPKVRFSSGPIHVYSTFSVNDYDRRNEDVDPVAASAEYELEKRVEKMHVFPVELMKGPEGLGLSIIGMGVGADAGLEKLGIFVKTITDNGAAARDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGLVKFQIGRERDPENSEVAQLIRLSLQADREKEERLKRQQEEYLRRTLDYSEDSTQPVSANSSVCEGPSSPVQVEHPMEVEATHSQEVESLKRLLQELVKLETTGNENELLSERLRQSERELGNIRKEAANLQNMLQQSQGQYMALDKKYNKAKRLVREYQQRELDMCHREEFYQQLLQEKDTEYNALVKKLKDRVINLEHELQETQRKAGFPVGLPYDSATLKLTPQMMRKTPPKPLFHKLETELSDTEISDLSPDGDGVKTATVERKVPVKDELDAAVPQHELLDNSINKTKIDLASRGGLANRQLPSANGNSSTSNGAAVDLGQLSNGNLLKRSRSNSRSSDCTLDDTDEEEEREGSALNLAGAPVAHETISLSNGNSHLLANVNNLLQHHPPAMATVIATPSNGHLGTTTPILLNSTSSASSSSSNQSTAREAQINQLYAQVHKDPSKQQHQQQQQQQQQAQAVTTSIPSIFKNALGSPADNGLNDFHRGSMTTFGTGPATSSNRDLNSSYDSILGSNDKLAENDPAESWMYPSRRRVAPNGSKVPLPGSSFTDQLNQALSDRERRLGDGSSRHSSDDYTEINKSQSAAAINCKTLINEIRQAVNEAQPKVPWQQQHHQQIQQQPSAHTTGPPSPTSMSSGCSSPGYSPSRTLDLSGSSSSFSDRKAMAAGYTYKGGPVHEWTKDQVGHWLMGIELERYIPVFKENNVEGGALLTLDSKDFKTLGICGDDKHRLKKRLKDLKANIEKERKDMERERREREKAIRKAEKKAAKKK
Protein: Phospholipid phosphatase-related protein type 4 (Brain-specific phosphatidic acid phosphatase-like protein 1) (Inactive 2-lysophosphatidate phosphatase PLPPR4) (Lipid phosphate phosphatase-related protein type 4) (Plasticity-related gene 1 protein) (PRG-1) (Q7TME0)
Organism: Mus musculus (Mouse)
Function: Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA)-mediated signaling pathways. Binds lysophosphatidic acid (LPA) and mediates its internalization into cells. Could act as receptor or a transporter of this lipid at the post-synaptic membrane. Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid-induced axon collapse (By similarity).
Subcellular location: Postsynaptic density membrane {ECO:0000269|PubMed:19766573, ECO:0000269|PubMed:26671989}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MQRAGSSGARGECDISGAGRLRLEQAARLGGRTVHTSPGGGLGARQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGAGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEDSMLQHRDALRSLTDLNQDPSRVLSAKNGSSGDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKESMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKSKNESRKMSLQVMDTEPEGQSPPRSIEMRSSSEPSRVGVNGDHHVPGNQYLKIQPGTVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNNQPRIMQVIAMSKQQGVLQSSPKNAEGSTVTCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSSTEGEGSGSWKWKAPEKSSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSVSSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
Protein: Stathmin-4 (Stathmin-like protein B3) (RB3) (Q9H169)
Organism: Homo sapiens (Human)
Function: Exhibits microtubule-destabilizing activity.
Subcellular location: Golgi apparatus {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Cell projection, axon {ECO:0000250}.
Interaction partners:
- Tubulin alpha-1B chain
- Tubulin alpha-1A chain
- Tubulin beta-2B chain
- Tubulin beta-2A chain
- Tubulin--tyrosine ligase
- Trafficking protein particle complex subunit 1
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit 3
- Trafficking protein particle complex subunit 6B
Sequence:
MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR