wanglab/gogpt-training-data huggingface dataset:
Protein: NAD-dependent protein deacetylase Sirt6 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 6) (dSirt6) (SIR2-like protein 6) (Q9VH08)
Organism: Drosophila melanogaster (Fruit fly)
Function: NAD-dependent histone deacylase that acts as a regulator of life span.
Subcellular location: Nucleus {ECO:0000269|PubMed:35091469}. Chromosome {ECO:0000269|PubMed:35091469}. Note=Predominantly nuclear; associated with chromatin. {ECO:0000269|PubMed:35091469}.
Interaction partners:
- Nicotinamide-nucleotide adenylyltransferase
- Glutamine-dependent NAD
- NAD
- purine-nucleoside phosphorylase
- NAD kinase 2, mitochondrial
- NAD-dependent protein deacylase Sirt4
- FI18188p1
- Histone H3
- Histone H3.3A
- NAD-dependent histone deacetylase sirtuin-1
Sequence:
MSCNYADGLSAYDNKGILGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFRGPKGVWTLEEKGEKPDFNVSFDEARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELHGNIYIEQCKKCRRQFVSPSAVETVGQKSLQRACKSSMDSKGRSCRSGILYDNVLDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIVPSGDLPLKNLKCGGKFVICNLQPTKHDKKANLIISSYVDVVLSKVCKLLGVEIPEYSEASDPTKQSKPMEWTIPTSNVNTFHRQYKKYVYFIYYLL
Protein: UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) (Q9VBI2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03172}. Nucleus {ECO:0000256|HAMAP-Rule:MF_03172}.
Interaction partners:
- Uracil phosphoribosyltransferase homolog
- Uridine kinase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- nucleoside diphosphate phosphatase
- Nucleoside diphosphate kinase
- Ribonucleoside-diphosphate reductase large subunit
- Uridine 5'-monophosphate synthase
- Nucleoside diphosphate kinase
- FI21821p1
- Nucleoside diphosphate kinase-like domain-containing protein
Sequence:
MWRALARTTLRAVANDCGSPGVGLAPSALTQHQLRHSKASNRFITTTSTAPPHNIGIMSVEKPKIVFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSEFGNLIEDYIRNGKIVPVEVTCSLLENAMKASGKSRFLIDGFPRNQDNLDGWNRQMSEKVDFQFVLFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASPDAEEVFGEVEKIFVASGF
Protein: LD05087p (Reduction in Cnn dots 1, isoform A (EC 3.-.-.-)) (A1Z9L0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSFFDCFNDFLQSGGNLVQNVSQEQEQKIADQELDGVIELMPPTTPTPSESSSTISAPSESSFSEKMEHSYMRDTPVRSDVHNGLTPARNILVRHPPQCPSCHTYPPQHEELSEIQQAHVPPYDEVVAKEAMNECARIAKYVKNNNSDEQDWVARVNKFNWTPMQEMVFEKVCSILDQDQLARLANDKRQHEPIHRRISSDKSASRFRKLLASVAWESRITQWIHALLMEHLSPSYMASYLEILQTLKTKLPTLVDKMLFGRPLNNSQELLAPVMKKRWEPNIMPKSRQLTHNAIMVVLPNMPTTGTVSDRMQKWYQALSTITQVVQISLPNTNNRIGNQNLDHVAETIVSITRVKINELRTENPSRGIILVGFNAGAALALQVALSESVACVVCMGFAYNTIRGPRGTPDDRMLDIKAPILFVIGQNSARTSQEEMEGLRERMQSESSLVVVGSADDALRVPKSKRRIEGVTQSMVDYMVVEEIFEFVNRTLSNPPGPRMPTCLMHQQGYQRLPKQSPHILADGNANKAVQQMRKRKMDGGLDDSMGQPSKTKFVPHNDAQDYGDAQTTAGGSASLPKVITPGVLGKQLPPVNLAAGTKIKMIPSSQFVQIKSLPSQSKLINYTLNKPSVGTSSTANIGSVVKTLPCSSVSGQQIITLKTPSGQTQQFATAATSTGAAGSSTSTGTGQKKYTVFKNANGMTMLHLTKSVPTTGSSSGSANMDLSNIIDMPIVFADNEGNIPEHQQADKDIKPAPIRSANKSPLIISQKIIKEANKPSGMVTSGSITAVSKPGNIVLNKGLQQLLNSSPGGTLATQNKVVYLNRSTIKPMGNVAPGTHRVPIRIVSTPNTGGAVTTTASSSPIMVDPATGSKVAKTVNVQTIKPTGSVLAQGTIRQAGNVGTKSYLQMINTAPGASKTVAGDGKGSVRNIYFKSATGLKQLPVQMLGNRIPGGAVISSTASASSGSPGLRRVVNIGPVSKVTATSTTSSSIAATLTHNKM
Protein: Elongator complex protein 6 (Protein TMEM103) (Q8BK75)
Organism: Mus musculus (Mouse)
Function: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Involved in cell migration.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q0PNE2}. Nucleus {ECO:0000250|UniProtKB:Q0PNE2}. Note=Concentrates in the nucleus upon insulin stimulation. {ECO:0000250|UniProtKB:Q0PNE2}.
Interaction partners:
- Elongator complex protein 4
- Elongator complex protein 5
- Elongator complex protein 3
- Elongator complex protein 2
- Elongator complex protein 1
- Cytoplasmic tRNA 2-thiolation protein 2
Sequence:
MFPELNNLLSTTPDKTEQGTLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALVQSFSHYNIVGQKLGVSLTAARDRGQLVFLEGLKSSVEVLFHSQDEPHPLQFLREAGTGNLQSLYTFIQDTLKPADSEESPWKYPVLLVDNLSVLLSLGVGAVAVLDFMQYCRATVCCELKGNVVALVHDTEGATDEGNDTLLNGLSHQSHLILRAEGLATGFCKDVHGQLSILWRRPSRSTAQRAQSLTYQYKIQDKNVSFFAKGMSPAVL
Protein: Exocyst subunit Exo70 family protein (Q9SF50)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Exocyst complex component SEC5B
- Exocyst complex component SEC5A
- Exocyst complex component SEC10b
- Exocyst complex component SEC6
- Exocyst complex component SEC8
- Exocyst complex component SEC10a
- Exocyst complex component SEC15B
- Exocyst complex component SEC3A
- Exocyst complex component EXO84C
- Exocyst complex component EXO84B
Sequence:
MRSKSGFSFFSKMTSSRKRPSLSLPSKSHESTDVNKTIDNAAEIIEKWNTEYVSDKKFYSLFCESKRDAKKFVKRVKELQNAMDLLIREDPNSEKLLRAQNLMQIAMKRLQKEFLQILSMNRAHLDPESISSRSPTSVVSNDDDVWHESRSAGDSIIEVEEVSKNSRTELKSIADCMIAAGCAKECATTYKSIRKSIVDESIYRLGVENISSSKAKKMPCEVVELKMNRWIEAVKVSMKTLFNGEKTLCDEIFESSVSLREFCFRDISKEGALLLFGFPETITLRDKKNPHPEKIFPLLDMYCTITDNLLAIEAIFSFPSISNVRTQAHSSLSRLSESILAHLMDFESQIRKDSSKTVVRGGGVHPMTISAMNHISRLAEYSNALINILKGSSSSSSAKALLPKSYFNVSESEESPVSELKARFAWMILVLLCKIDGKAEMYKDFSMQYLFLANNLQHVVSRARSTNVKHVLGNDWIAKNSEKVRQFARSYERLAWGPLASMCPAISTSEAVEMSPEEAMMQFKKFNETFESTCEAQSECIVLDPKLLDEMRISIGRKLLPVYRDFYNAHRNAVMLAGTEGQWNVRYNPEDIGNHLSELFSGKGISEKGYVCTPDFCVTTPTPTPVRKTRSLSCRRF
Protein: glutathione transferase (EC 2.5.1.18) (G9J6Q5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
Protein: SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein) (Protein Solo) (Q86VW0)
Organism: Homo sapiens (Human)
Function: May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
Interaction partners:
- Short transient receptor potential channel 5
- Short transient receptor potential channel 4
- Dapper homolog 1
Sequence:
MEASVILPILKKKLAFLSGGKDRRSGLILTIPLCLEQTNMDELSVTLDYLLSIPSEKCKARGFTVIVDGRKSQWNVVKTVVVMLQNVVPAEVSLVCVVKPDEFWDKKVTHFCFWKEKDRLGFEVILVSANKLTRYIEPCQLTEDFGGSLTYDHMDWLNKRLVFEKFTKESTSLLDELALINNGSDKGNQQEKERSVDLNFLPSVDPETVLQTGHELLSELQQRRFNGSDGGVSWSPMDDELLAQPQVMKLLDSLREQYTRYQEVCRQRSKRTQLEEIQQKVMQVVNWLEGPGSEQLRAQWGIGDSIRASQALQQKHEEIESQHSEWFAVYVELNQQIAALLNAGDEEDLVELKSLQQQLSDVCYRQASQLEFRQNLLQAALEFHGVAQDLSQQLDGLLGMLCVDVAPADGASIQQTLKLLEEKLKSVDVGLQGLREKGQGLLDQISNQASWAYGKDVTIENKENVDHIQGVMEDMQLRKQRCEDMVDVRRLKMLQMVQLFKCEEDAAQAVEWLSELLDALLKTHIRLGDDAQETKVLLEKHRKFVDVAQSTYDYGRQLLQATVVLCQSLRCTSRSSGDTLPRLNRVWKQFTIASEERVHRLEMAIAFHSNAEKILQDCPEEPEAINDEEQFDEIEAVGKSLLDRLTVPVVYPDGTEQYFGSPSDMASTAENIRDRMKLVNLKRQQLRHPEMVTTES
Protein: Daydream (Death associated molecule related to Mch2 caspase, isoform A (EC 3.4.22.-)) (Death associated molecule related to Mch2 caspase, isoform B) (Q7KHI6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- AT03047p
Sequence:
MYLPERTEHQKIERLYDSNRVNAEPGQGLDLNEKLKPPAVYILNHEQFPQDSQLNRKGSSNDVNALRKTFESLKCRVEVISNPALPDVKNKVKEWSAKRFTQDAGFVLFILSHGDRKEKILACDHREYHLDDDVLFPLFRNPTLSGKPKILIVQACKGPLRADAKKMNNEPYIKCYSCSEGYLSYRNENHGSVFIQTLCEAMDQYGLTRDFQSIFKHVKAEVERRSTMTGSKQVPSEESHNFDKPFYFGNYAKNT
Protein: Contig An12c0040, genomic contig (A2QYG9)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Interaction partners:
Sequence:
MSYGGNQGGYGQYNPYGQQDANPYSDANAMEQGNGSYEMGSYNQPADATTLLNKCREINDGIADLRAKREGQLAAAQNALLDSSTGKEDQVARQTLDYIEDEVNNGFRYLRDLLKKVKQTPGSGDSRVQTQIDVTSRNLRREIEQYQRCQSDFQKRLREQVRRRYEIANPEASPEEIEQGVDNVLLGQEQSFQVTGSRTRQANDARQAALERSAAIRKIEQDMMELGRLYQEVAELVHQQEPAVEQINQDADNVAQNVSNANNQITEAIASARRARKWKWYALLVVILIIAIVVGVAVGVTEANKSSK
Protein: Serine/arginine repetitive matrix protein 4 (Neural-specific serine/arginine repetitive splicing factor of 100 kDa) (Neural-specific SR-related protein of 100 kDa) (nSR100) (Q8BKA3)
Organism: Mus musculus (Mouse)
Function: Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts. Promotes alternative splicing of REST transcripts to produce REST isoform 2 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells. Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system. Regulates alternative splicing events in genes with important neuronal functions.
Subcellular location: Nucleus {ECO:0000269|PubMed:19737518}.
Interaction partners:
- Polypyrimidine tract-binding protein 2
- RNA-binding protein Nova-1
- RNA-binding protein Nova-2
Sequence:
MASLQQGEKQLFEKFWKGTFKAVATPRPESIIVASITARKPMPRTEPQSSLLLPDQDGPSEKLGQHLAPEALGTNSWGREKACRELDPARAHSASQDRDPTPPPSSRGKKKKKKSTRKKRRRSPSYSPSPVKKKKKKSSKKHKRHRSFSKKRRHSSCSPKSKRREEKRHKKQSRSRKSHRHRHHRCPSRSQSSELRSPSCESRHRGRSPEEGRKSRRTHSRRCSKNHCKVSPDARSSHLPSQPLPRLGFLSARGVITGSGSAADLFSKSASPLAATRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPGGDLSKSRDLNCGNTSDSGNSFTTSSPQNKGAVLETVSPACRSRESRGFQSPCLQCAEVKKSSLVPSTARSSPIKECSRSSSYTSTRSSSPSSRSPNPRASPRYTRSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDLKYGEKEPQPRERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSSSLSSASSWYSSSSSSSSSSSRSPSRSYSRSRSPSRSHSSRSQTRSRTRTSRSSSSRSLSLGSRSRSRNRSLSYSSAESYASTRR
Protein: O-fucosyltransferase 31 (O-FucT-31) (EC 2.4.1.-) (O-fucosyltransferase family protein) (Q7Y030)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLQMKQPLQNLNQSQKTALAGVFVLLFPILYPNLFSPLGRASPSLFSEWNAPRPRHLSLLQGALDRQISIRQQVELWSPLADQGWKPCTESYRGASLPEKSEGFLQVFLDGGLNQQRMGICDAVAVAKIMNVTLVIPRLEVNTVWQDSSSFTDIFDLDHFISVLKDEVRIVRELPIQYAWSTRDYYATGIRATRIKTAPVHASAEWYLENVLPIIQSYGIAAVAPFSHRLAFDNLPESIQRLRCKVNFEALNFVPHIRELGDALVHRLRNPPSSSQTSGTMDPTDRINTIVKAGAGKFAVLHLRFDKDMAAHSGCDFEGGKAEKLALAKYRQVIWQGRVLNSQFTDEELRNKGRCPLTPEEIGLLLSALGFSNNTRLYLASHQVYGGEARISTLRKLFPGIENKKSLASAEELADVQGKASLMAAVDYYVSMKSDIFISASPGNMHNALQAHRAYLNLKTIRPNMILLGQVFVNKSLDWSEFEGAVMNGHKNRQGQLRLRKQKQSIYTYPAPDCMCKVA
Protein: EG:196F3.2 protein (O76889)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSTVFINSRKSPNVLKKQGTDQWVKLNVGGTYFLTTKTTLSRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPKYFAPVLNYLRHGKLVLDGVSEEGVLEEAEFYNVTQLIALLKECILHRDQRPQTDKKRVYRVLQCREQELTQMISTLSDGWRFEQLISMQYTNYGPFENNEFLCVVSKECGTTAGRELELNDRAKVLQQKGSRINTISHSATPTQHQLDAAKEARATATATSNTTNHTRSDQTQPQAQITHQDQPESPKQSPQGDYASFAFETKLTGTTAIRFSPLWPFCALYEVCAGVHVFNL
Protein: 40S ribosomal protein S3 (Q6FNJ4)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Large ribosomal subunit protein uL23
- RP41
- Eukaryotic translation initiation factor 1A
- 40S ribosomal protein S8
- Small ribosomal subunit protein eS21
- Small ribosomal subunit protein bS6m
- Large ribosomal subunit protein eL38
- 60S ribosomal protein L6
- 40S ribosomal protein S30
- Eukaryotic translation initiation factor 2 subunit gamma
Sequence:
MVSLISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDVATRHVLMRQGVLGIKVKIMRDPATNRGGPRALPDAVSIVEPKDEEPVLTPTVRDYRSAEEVGEKTEAPAEQAVEASA
Protein: Uridylate kinase (UK) (EC 2.7.4.22) (Uridine monophosphate kinase) (UMP kinase) (UMPK) (P0A7E9)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9922246}. Note=Is predominantly localized near the bacterial membranes.
Interaction partners:
- Ribosome-recycling factor
- Elongation factor Ts
- Uracil phosphoribosyltransferase
- Small ribosomal subunit protein uS2
- Orotidine 5'-phosphate decarboxylase
- Nucleoside diphosphate kinase
- Uridine kinase
- 5'/3'-nucleotidase SurE
- CTP synthase
- Protein UshA
Sequence:
MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
Protein: Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase) (P40369)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Argininosuccinate synthase
- Protein arg11
- Probable argininosuccinate lyase
- Adenylosuccinate lyase
- Ornithine carbamoyltransferase, mitochondrial
- Amino-acid acetyltransferase, mitochondrial
- Arginase
- Arginase
- Probable citrate synthase, mitochondrial
- Probable isocitrate dehydrogenase, mitochondrial
Sequence:
MAEKSSKKLWGGRFSGATDPLMAEFNKSIYSGKEMCEEDVIGSMAYAKALCQKNVISEEELNSILKGLEQIQREWNSGQFVLEPSDEDVHTANERRLTEIIGDVAGKLHTGRSRNDQVTTDLRLWLCRKIKEVEVYVINLLKVFTNRAEMEIDVIMSGYTHLQRAQPVRWSHFLMSHALPLLGDLGRLRQLYTRVSQLPLGAGALAGNPFNVDREFLRKELGFEGIIMNSMNAVGDRDFVIEFMFWAGMVMLHISRFAEDLIIYSSSEFGFVTLSDAYSTGSSIMPQKKNPDSLELLRGKSGRVLGDMIGLMITVKGTPTTYNKDLQEDKEPLFDAFKTVSDSLQILTGVVSTLTINPTKIAESLTPDLLATDLAEYLVRKGLPFRQTHHISGSAVRMAEERNTTLDKLSVSDLQSLHPLFDEDVSKVFNYEESVEKRCSIGGTAKHCVQEQIEHIRSAIL
Protein: 3-hydroxyacyl-CoA dehydrogenase type-2 (Q9CYT3)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAAAVRSVKGLVAVVTGGASGLGLATAKRLVGQGATAVLLDVPDSEGEAQAKKLGESCIFAPANVTSEKEIQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPTGIRVVTIAPGLFATPLLTTLPEKVRNFLASKVPFPSRLGDPAEYAHLVQTIIENPFLNGEVIRLDGAIRMQP
Protein: Conserved protein (O53486)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- DUF2784 domain-containing protein
- Nicotinamidase/pyrazinamidase
- Probable sugar-binding lipoprotein
- Conserved protein
- O-acyltransferase WSD1 C-terminal domain-containing protein
- Uncharacterized protein Rv1836c
- Uncharacterized protein Rv2876
- Cell wall hydrolase ChiZ
- Uncharacterized protein Rv0479c
- Protein Rv3035
Sequence:
MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVGSQPQVGHEAIGRFYDTFIGPRDITFHRDLDIVSGTVVLRDLELEVAMDSAVTVFIPAFLRYDLRPVTGEWQIAALRAYWELPAMMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAGRRHKKLVETFLNAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGASWTKVTGAGSTVAVSLASDHRRGIMFADVPWRGNRINRIRYFPA
Protein: Vitellogenesis-inhibiting hormone (VIH) (P83627)
Organism: Armadillidium vulgare (Pillbug) (Pill woodlouse)
Function: Inhibits secondary vitellogenesis in females. Has no hyperglycemic or molt-inhibiting activity.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
YNIPLGWGRRDMPGCLGVLGNRDLYDDVSRICSDCQNVFRDKNVESKCRSDCFSTSYFETCIMALDLAEKISDYKLHASILKE
Protein: ABSCISIC ACID-INSENSITIVE 5-like protein 6 (Abscisic acid responsive elements-binding factor 3) (ABRE-binding factor 3) (Dc3 promoter-binding factor 5) (AtDPBF5) (bZIP transcription factor 37) (AtbZIP37) (Q9M7Q3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to the ABA-responsive element (ABRE). Mediates stress-responsive ABA signaling.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- Serine/threonine-protein kinase SRK2D
- Serine/threonine-protein kinase SRK2E
- Serine/threonine-protein kinase SRK2I
- E3 ubiquitin-protein ligase KEG
- Basic leucine zipper 8
- Low-temperature-induced 65 kDa protein
- Dehydration-responsive element-binding protein 2C
- Dehydration-responsive element-binding protein 1A
- Dehydration-responsive element-binding protein 2A
- Serine/threonine-protein kinase SRK2C
Sequence:
MGSRLNFKSFVDGVSEQQPTVGTSLPLTRQNSVFSLTFDEFQNSWGGGIGKDFGSMNMDELLKNIWTAEESHSMMGNNTSYTNISNGNSGNTVINGGGNNIGGLAVGVGGESGGFFTGGSLQRQGSLTLPRTISQKRVDDVWKELMKEDDIGNGVVNGGTSGIPQRQQTLGEMTLEEFLVRAGVVREEPQPVESVTNFNGGFYGFGSNGGLGTASNGFVANQPQDLSGNGVAVRQDLLTAQTQPLQMQQPQMVQQPQMVQQPQQLIQTQERPFPKQTTIAFSNTVDVVNRSQPATQCQEVKPSILGIHNHPMNNNLLQAVDFKTGVTVAAVSPGSQMSPDLTPKSALDASLSPVPYMFGRVRKTGAVLEKVIERRQKRMIKNRESAARSRARKQAYTMELEAEIAQLKELNEELQKKQVEIMEKQKNQLLEPLRQPWGMGCKRQCLRRTLTGPW
Protein: Exostosin-like 2 (EC 2.4.1.223) (Alpha-1,4-N-acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) [Cleaved into: Processed exostosin-like 2] (Q9UBQ6)
Organism: Homo sapiens (Human)
Function: Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Processed exostosin-like 2]: Secreted. Note=A soluble form is found in the serum.
Interaction partners:
- Exostosin-like 3
- X-box-binding protein 1
- Glycosaminoglycan xylosylkinase
Sequence:
MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGKSTMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMISQFGFPYANYKRKI
Protein: Type IV inositol polyphosphate 5-phosphatase 11 (At5PTase11) (EC 3.1.3.36) (EC 3.1.3.86) (Q5EAF2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has phosphatase activity toward PtdIns(4,5)P2, and in vitro toward PtdIns(3,5)P2 and PtdIns(3,4,5)P3. Cannot dephosphorylate PtdIns(5)P, Ins(1,4,5)P3 and Ins(1,3,4,5)P4.
Subcellular location: Cell membrane; Peripheral membrane protein {ECO:0000269|PubMed:18392779}.
Interaction partners:
- Phosphatidylinositol 4-kinase gamma 6
- SAUR-like auxin-responsive protein family
- Protein PSY1
- NAC domain containing protein 58
- Chromophore lyase CRL, chloroplastic
- Auxin-responsive protein-like protein
- Putative lipid phosphate phosphatase 3, chloroplastic
- Diacylglycerol kinase 6
Sequence:
MPTMGNKNSMCGLKRFPNYKKSPIGSFAKNSSSHDGIKTIEAVNSCSFSRKADLCIRIITWNMNGNVSYEDLVELVGKERKFDLLVVGLQEAPKANVDQLLQTASSPTHELLGKAKLQSVQLYLFGPKNSHTLVKELKAERYSVGGCGGLIGRKKGAVAIRINYDDIKMVFISCHLSAHAKKVDQRNTELRHIANSLLPRDKRKRDLTVWLGDLNYRIQDVSNHPVRSLIQNHLQSVLVSKDQLLQEAERGEIFKGYSEGTLGFKPTYKYNVGSSDYDTSHKIRVPAWTDRILFKIQDTDNIQATLHSYDSIDQVYGSDHKPVKADLCLKWVNS
Protein: Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump) (Q64436)
Organism: Mus musculus (Mouse)
Function: The catalytic subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Uses ATP as an energy source to pump H(+) ions to the gastric lumen while transporting K(+) ion from the lumen into the cell. Remarkably generates a million-fold proton gradient across the gastric parietal cell membrane, acidifying the gastric juice down to pH 1. Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2). The release of the H(+) ion in the stomach lumen is followed by binding of K(+) ion converting the pump conformation back to the E1 state (By similarity).
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:P20648}; Multi-pass membrane protein {ECO:0000255}. Note=Localized in the apical canalicular membrane of parietal cells (By similarity). {ECO:0000250|UniProtKB:P20648}.
Interaction partners:
- Potassium-transporting ATPase subunit beta
- Inorganic pyrophosphatase
- Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
- Inorganic pyrophosphatase 2, mitochondrial
- Potassium-transporting ATPase alpha chain 2
- Sodium/potassium-transporting ATPase subunit beta-1
- V-type proton ATPase subunit d 2
- Gastrin
- V-type proton ATPase subunit a
- H
Sequence:
MGKAENYELYSVELGSGPGGDMTAKMSKKKAGGGGGKKKEKLENMKKEMEINDHQLSVSELEQKYQTSATKGLKASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAVALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILSAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTAQGLVVSTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFVVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSINKFQLSIHTLEDPRDSRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRMPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFADYFTAMAQEGWFPLLCVGLRPQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEMCQIADVLIRKTRRLSVFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPMPFGLLIFVYDEIRKLGVRCCPGSWWDQELYY
Protein: LuxR (Q8GBU2)
Organism: Vibrio harveyi (Beneckea harveyi)
Interaction partners:
Sequence:
MGSIAKRPRTRLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDEVLNHVVRQFSNFLSDNIDLDIHARENIANITNAMIELVSQDCHWLKVWFEWSASTRDEVWPLFVTTNRTNQLLVQNMFIKAIERGEVCDQHEPEHLANLFHGICYSIFVQANRSKSEAELSTLVSAYLDMLCIYNREHH