wanglab/gogpt-training-data huggingface dataset:
Protein: Heat shock protein 90 (Q8IC05)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- HSP90 co-chaperone p23
- Heat shock 70 kDa protein
- Heat shock 70 kDa protein
- Endoplasmic reticulum chaperone GRP170
- Peptidyl-prolyl cis-trans isomerase, putative
- Activator of Hsp90 ATPase
- Hsp70-Hsp90 organising protein
- Endoplasmic reticulum chaperone BIP
- Heat shock protein 70
- Heat shock protein 110
Sequence:
MSTETFAFNADIRQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESITDTQKLSAEPEFFIRIIPDKTNNTLTIEDSGIGMTKNDLINNLGTIARSGTKAFMEAIQASGDISMIGQFGVGFYSAYLVADHVVVISKNNDDEQYVWESAAGGSFTVTKDETNEKLGRGTKIILHLKEDQLEYLEEKRIKDLVKKHSEFISFPIKLYCERQNEKEITASEEEEGEGEGEREGEEEEEKKKKTGEDKNADESKEENEDEEKKEDNEEDDNKTDHPKVEDVTEELENAEKKKKEKRKKKIHTVEHEWEELNKQKPLWMRKPEEVTNEEYASFYKSLTNDWEDHLAVKHFSVEGQLEFKALLFIPKRAPFDMFENRKKRNNIKLYVRRVFIMDDCEEIIPEWLNFVKGVVDSEDLPLNISRESLQQNKILKVIKKNLIKKCLDMFSELAENKENYKKFYEQFSKNLKLGIHEDNANRTKITELLRFQTSKSGDEMIGLKEYVDRMKENQKDIYYITGESINAVSNSPFLEALTKKGFEVIYMVDPIDEYAVQQLKDFDGKKLKCCTKEGLDIDDSEEAKKDFETLKAEYEGLCKVIKDVLHEKVEKVVVGQRITDSPCVLVTSEFGWSANMERIMKAQALRDNSMTSYMLSKKIMEINARHPIISALKQKADADKSDKTVKDLIWLLFDTSLLTSGFALEEPTTFSKRIHRMIKLGLSIDEEENNDIDLPPLEETVDATDSKMEEVD
Protein: ARID domain-containing protein (J7SA49)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- SWI/SNF chromatin remodeling complex core catalytic subunit swsn-4
- SWI/SNF complex subunit SMARCC2
- SWI/SNF Subunit INI1 DNA binding domain-containing protein
- HMG box domain-containing protein
- Bromo domain-containing protein
- SWI/SNF chromatin-remodeling accessory subunit 2
- Zinc finger protein dpff-1
- Actin-related protein 4
- SWI/SNF chromatin-remodeling accessory subunit 1
- SWI/SNF chromatin remodeling complex subunit swsn-7
Sequence:
MPGDDNAVGTETNEDKPTTSNAVTAENPSRGDESQQQQQQPQQQQKRGEDADKYAASVAEVAHGGGGPKKDDQVPPAPDASMPTPQQQQQQPNLPPPQQPYEHPAQQHPPQHHSVPPNSFAPPPGQHHPQHPGMPPMEWRPPGAEYQMPPGYPAGYPPYGMPPRHHPGYPHPAYGYPPPGAPYGYPPQMMRPPMMAPGDMVRMPPGPTPTEWAAQQQAQAASRSVPPKEGPNGNPATPSSSSQPIPSPSASSIAEESLDDKPSGTKMPAQPPPQQHPPPPQPQQIMSPMPPQAPPSQQATPSSSAASVAAPDTPKVSGKVLSKAELFEKLVGPITLHNPMKVMAERRGFFERLIEFCEHNGEPLTMVPQVSKQSIDLHRLYIGVRAKGGFQQVTKDKYWKNLCTEANPDLAESSAAGYQLRKHYQRHLLMLECRETGRNPEDEVAFADKMKRQRKREPAGGNAAAAAAVAAAQQGDQKSQHGAPGGSGAPPPGPPGAYPGNGAPGGPPGGPPQFPGHPGMDPNYHYYQQHGMMPPHPGHPGYPPQHMNAFSPGQYPGHQRPPGGPGGPPPGPQAMRAPMPQHMQEMDEHQRQWYAHQQAAAAHHHAQQQAAAQAQAAQAQQASTPAPSTTPAPQAASSSQAAPTSGANTQPATPSASNQPPTPASASASTTLHVEPASVAGGSQAGSRAPSAGPGPSATPDSSTIPSASAAADAQTTTSSETSTPGEPTSSTPSDTPAPSTSVPPPTSVQPPQPQQPPQGPPGPPGPQQHPGPYPGYPGYGPPGAMRPPAGFAPPPGAPYGYPPGAPPPAGFHPSHPQHPQHAQYLAWQQQRYHQQQQHQQQQQQGAPGGPRPPYPYPGGPVPPGPPQNRMPPPPPAQGAPSPSGAAGSNGKQPRYGTPAPPSRASAPTPQPLSSTMPVVAPSTSTQPTPTTGSYLANTLATPGPAHAPSSSMSHAHHVISQQQHQYPPGCIEATATSQNQVKRRKVYARELINATPRRLIMSLRSGLDAEAIWAINALNVLLYDDTNPHPTLQQMPGLVNVIVEHLYATLSIMYPAEFQLTEPGKPIIMDESKETVEKMMKAEKDGGIKSIIEKMPVVPRKGSDKTATFTMMSRNGLQVHFRDESIPTALRKRFSRESGEKNSDAMVDHSISSAYVEDRNSVGLGGGLAERIATRLRDKLLHEKTRPRPVFSKYLDDLETESTETIDTVEVKKEIEDEVAEEKKDVLLMRGARPDELSDCKHEVELAWPRPTALSPKSQAMEELAHRALALSNILRGFSFVAGSDVLMARNEALLFIIGRLLKLNVKEHKISSKRPGIVMSAEELKTAPKQLSADEKRAKEKSVLDEVDATTAQMVETANQLRDDAFVMLTHMSVSLNLVDLPDAIAYPIYDGLLRWSVSRVPEATDSSIPCPVSPRDYSLEIMCKMVVIERNVDMFLSTGSWSRVEQFVHILTRLLTMNEETHYREFAIVILNALCIASEAVCYICAMETSAIAHLILFIDSADQNMHQVMQAHGMAALRDNPELMGTSVGMLRRAASMLRLLVKVPKAYKIYMKHQTRLLQFTMSQLMDSRVAGMIADTLYEIQEFVKEFGEDVPEPLKITYSEGYQPSQTDDKESTSTNSDAAAPPQKSTSSSPKPVEESAATTSVNVHGNGTLECETSSRPLSSEAAAAVITPYENHHKNEEEEDLKKEIDEGESCDGYDTEAIRLSQKRSAAALIDEQSRSPPPAKRAHLSNGFDKSKSSVSTNGTLGDASQNDGALTTAVA
Protein: Peroxisome proliferator-activated receptor alpha (Nuclear receptor subfamily 1 group C member 1) (F1D8S4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
Protein: Cystathionine beta-lyase MetC (CBL) (CL) (EC 4.4.1.13) (Beta-cystathionase MetC) (Cysteine desulfhydrase MetC) (CD) (EC 4.4.1.28) (Cysteine lyase MetC) (Cysteine-S-conjugate beta-lyase MetC) (P06721)
Organism: Escherichia coli (strain K12)
Function: Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine. In addition, under certain growth conditions, exhibits significant alanine racemase coactivity.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- Cysteine synthase A
- Protein MalY
- Cystathionine gamma-synthase
- 3-mercaptopyruvate sulfurtransferase
- Methionine synthase
- Homocysteine S-methyltransferase
- Bifunctional aspartokinase/homoserine dehydrogenase 2
- S-ribosylhomocysteine lyase
- 5,10-methylenetetrahydrofolate reductase
Sequence:
MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARIV
Protein: Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) (Q9UHC6)
Organism: Homo sapiens (Human)
Function: Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
Subcellular location: Membrane {ECO:0000250|UniProtKB:Q9CPW0}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000250|UniProtKB:Q9CPW0}. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:Q9CPW0}. Note=Expressed in the juxtaparadonal region. {ECO:0000250|UniProtKB:Q9CPW0}.
Interaction partners:
- Contactin-2
- Leucine-rich glioma-inactivated protein 1
- Potassium voltage-gated channel subfamily A member 2
- Potassium voltage-gated channel subfamily A member 1
- Forkhead box protein P2
- Neuroligin-3
- Neuroligin-4, X-linked
- Disintegrin and metalloproteinase domain-containing protein 22
- A-type potassium channel modulatory protein DPP6
- Inactive dipeptidyl peptidase 10
Sequence:
MQAAPRAGCGAALLLWIVSSCLCRAWTAPSTSQKCDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI
Protein: Chloroplastic import inner membrane translocase subunit TIM22-2 (Hypothetical outer plastid envelope protein of 20 kDa) (Hypothetical protein 20) (Q94EH2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Together with HP30-1 and HP30-2, triggers the import and insertion of transit sequence-less multi-pass transmembrane proteins (e.g. CEQORH) into the chloroplastic inner membrane.
Subcellular location: Plastid, chloroplast outer membrane {ECO:0000269|PubMed:24248378}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM23-1
- Mitochondrial import inner membrane translocase subunit TIM23-3
- Mitochondrial import inner membrane translocase subunit TIM23-2
- Mitochondrial import inner membrane translocase subunit TIM50
- Outer envelope pore protein 16-3, chloroplastic/mitochondrial
- Chloroplastic import inner membrane translocase subunit HP30-1
- Chloroplastic import inner membrane translocase subunit HP30-2
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM8
- Probable mitochondrial import inner membrane translocase subunit TIM21
Sequence:
MAANDSSNAIDIDGNLDSDSNLNTDGDEATDNDSSKALVTIPAPAVCLFRFAGDAAGGAVMGSIFGYGSGLFKKKGFKGSFADAGQSAKTFAVLSGVHSLVVCLLKQIRGKDDAINVGVAGCCTGLALSFPGAPQALLQSCLTFGAFSFILEGLNKRQTALAHSVSLRHQTGLFQDHHRALPLSLALPIPEEIKGAFSSFCKSLAKPRKF
Protein: UBA domain-containing protein 3 (O74345)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- PH and SEC7 domain-containing protein C11E3.11c
- ADP-ribosylation factor 6
- Kinesin-like protein 8
Sequence:
MSGRRNETAIRELVQSVSGNNLCADCSTRGVQWASWNLGIFLCLRCATIHRKLGTHVSKVKSISLDEWSNDQIEKMKHWGNINANRYWNPNPLSHPLPTNALSDEHVMEKYIRDKYERKLFLDENHSTNSKPPSLPPRTKSSSQSSPMASTSTSKSRYADSLSTLHDMGFSDDSVNTHALEETNGDVTRAIEKIVQHGSSKPQKPSTLTSTKSTIKLVSARLKKRNKNLSVHFEDGTKPGDAYEVTGDTRAASPTLNPFEQMMAMTNQGMSVSPGVETTSSPFFTAPVEPNQPLQPLRPSMTGPVPSSMGSEATLNMPSTYGIDSNLYTNSNSSSIVQNPLQPARTGPAAINYNYTTNYSVSSPSVTNPFFDVGSSTQNASLMGSTGYPSSANNVYYENSYQGVGTSMSDNYQLPDMSKLSLNEQPAAPSNSNSQYMNTSMPTLDSTNMYGQSNQDPYSMSNGVYGSNYSAQPSTMQMQATGIAPPQPNMSMQMPMSMQSTGYQMPMENTWVDYNGMSQQGNGMQPATMNYSNSMGYDTNVPADNGYYQQGYGNVMMPPDASYTGTGSYVQPMNQPSGGMGAPADSSKADSYIQRIMQGKQ
Protein: Uncharacterized protein (Q57WV9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSVLSEWRREWTTEAHAHRQRLTKNALQRNLREDVQRRVTSSSVSSSIAVVDCCWSRGQCPCDTTPSVTTALAPYLFCALEDGVVCVINTSNFAKTYLFEDDSLHRREKERAGRKETTPQHDTQRDRLVAIDCFPLQQKPKREVTATKQVAGQPTVADSEVISLLCTVVDGFVCTFTIDAVTISRARSHSLKASNVCRAIKLPADTDLSDRGSWKTFSIRFSQQGSRIIVLATSTGPPTRNPTAFSNTAGSRAGLIYTTFLCVLKRQENDANGVYAVEKQWTKVLPPNGDTTTELLCVTWWDDEESVILVVWSDGTVCLMDVALSTIAQSVMFSSAEDLRPGRVVKAVASPPSFQGAPASRTSTSTPSAVSATVTSGTSNCSRPTGLLAVVVDENIIVQFAVHSSLHKNEPTSSEEPPLKTQKVESPSQGEMDSPTLTLEPGPQTHCSEDIPIGDIAIFDCLLPHTLCVLLESGALLILDGTTVEILYQRQLSRLFPSKVTRRATSGADGGSNDKRSGNSRECSFLLRPKDRPLTMCILEHNTAVILRAS
Protein: Zinc finger protein 692 (AICAR responsive element binding protein) (Q9BU19)
Organism: Homo sapiens (Human)
Function: May act as an transcriptional repressor for PCK1 gene expression, in turn may participate in the hepatic gluconeogenesis regulation through the activated AMPK signaling pathway.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein cereblon
Sequence:
MASSPAVDVSCRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPLPPKGLQYLVLLSHAHSRECSLVPGLRGPGGQDGGLVWECSAGHTFSWGPSLSPTPSEAPKPASLPHTTRRSWCSEATSGQELADLESEHDERTQEARLPRRVGPPPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEPDAPRLLPSPVTCTPKEGETPPAPAALSSPLAVPALSASSLSSRAPPPAEVRVQPQLSRTPQAAQQTEALASTGSQAQSAPTPAWDEDTAQIGPKRIRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFSCPEPACGKSFNFKKHLKEHMKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHQRKHAETVAALRFPCEFCGKRFEKPDSVAAHRSKSHPALLLAPQESPSGPLEPCPSISAPGPLGSSEGSRPSASPQAPTLLPQQ
Protein: Sigma-54 dependent DNA-binding response regulator Nla19 (Q1DDD5)
Organism: Myxococcus xanthus (strain DK1622)
Interaction partners:
- histidine kinase
- Selenocysteine-specific elongation factor
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- RNA polymerase sigma-54 factor
- Chemotaxis protein CheA
- Phosphoribosyl transferase domain protein
Sequence:
MTDANTPPTRGRLLVVDDQRNMRATTALLLRAENYTVFEAATGEEALAQLASGSIDLLLTDLKMEPMDGLTLLRRALEVAPRLQVIMMTAFGSIESAVEAMRLGAYDYVTKPFKESELRYRVERALERARLQRDVDNLTTDFNQRHGLSALVGRSAAMRELTTRLMRVAQSDATVLIQGESGTGKELVARALHAHSRRKARSFVPVNCAAISESLLESELFGHAKGAFTGAVKSRRGLFEEADGGTLFIDEVTETSPTFQSKLLRALQEGEVRRVGESTALRVDVRIVAATNRDIELEVRDKRFRQDLYYRLNVVALRVPPLRERLEDVPALAEHFLERANARSPNPKRLSAAAVSHLMSYGFPGNVRELENLVEQAAALAEGDELLPEDFPVRQGRMTPAHGTPSVAFLDGQGGALGRNASAGPTLAQVVEEAERHAITQALERHGVDLARVADELGVSSTTLWRKMKRLNLRPPSELARE
Protein: Jindongenin-1a (Jindongenin-1) (G3ETQ2)
Organism: Amolops jingdongensis (Chinese torrent frog)
Function: Displays broad-spectrum antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Also displays antifungal activity against C.albicans ATCC 2002. Has low hemolytic activity, low cytotoxicity and low antioxidant activity.
Subcellular location: Secreted {ECO:0000269|PubMed:21816202}.
Interaction partners:
Sequence:
MFTLKKPLLLLFFLGTVSLSLCEQERAADDDEGEVIEEEVKRDSMGAVKLAKLLIDKMKCEVTKAC
Protein: Copper-binding regulatory protein cuf2 (Copper homeostasis protein) (O94588)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Uncharacterized MFS-type transporter C947.06c
- Meiotic fizzy-related protein 1
- Copper transport protein ctr6
- UPF0494 membrane protein C1348.01
- Uncharacterized transporter mfc1
- Copper transport protein ctr5
- Putative fatty acid elongase 1
- Copper transport protein ctr4
- mRNA export factor crp79
Sequence:
MIIIDGKNYACVVCLRGHRGSSCQHQERALIEVRTRGRPLLCKKCRAIKQQLKSNLKCVCHLQPFLPFANEYQELLNFTQKNPILASLFLFSTDKDIMNSSLNPASQAYTFDLGRTLPISEDILGYRKPLSLTDASNRIDASQLNEKENDSFTINQEADIFNFAKYLHSKDDISGIP
Protein: Uncharacterized protein, isoform A (Uncharacterized protein, isoform B) (Q9VSZ0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GEO12018p1
- FI09328p
Sequence:
MGNISSNIRAIEDESYELSSEIWAVDMEITDSETDDVPVSRSVSVSANVSGNVSGNVSGKVSGNARGAFSGTLSQTVSATVSGTVSATVIGLVINEFVPMPFSGTLSGILSGTLSGTVEGTISRTVDGAVSTTGSGTIEGTVSGTVKGTVRGAINGTISGTISGTASGTVRRTADGKLIFETGARLNNRKFIIHEICGMNCEITL
Protein: Protein kinase A catalytic subunit isoform 2 (Q38DS1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Protein kinase A regulatory subunit
- Cyclic nucleotide-binding domain-containing protein
- cAMP binding protein
Sequence:
MPVATSTEPQTYVFTKPDTSGWKLSDFEMGDTLGTGSFGRVRIAKLKSRGEYYAIKCLKKREILKMKQVQHLNQEKQILMELSHPFIVNMMCSFQDENRVYFVLEFVVGGEVFTHLRSAGRFPNDVAKFYHAELVLAFEYLHSKDIIYRDLKPENLLLDGKGHVKVTDFGFAKKVTDRTYTLCGTPEYLAPEVIQSKGHGKAVDWWTMGVLLYEFIAGHPPFFDETPIRTYEKILAGRFKFPNWFDSRARDLVKGLLQTDHTKRLGTLKDGVADVKNHPFFRGANWEKLYGRHYHAPIPVKVKSPGDTSNFESYPESGDKRLPPLAPSQQLEFRGF
Protein: Outer surface protein A (P0CL66)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Induces host (human and mouse) cytokine release by monocyte cell lines via TLR2 and CD14; nonlipidated protein does not stimulate host cells.
Subcellular location: Cell outer membrane {ECO:0000305|PubMed:2761388}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303, ECO:0000305|PubMed:10426995}. Cell surface {ECO:0000305|PubMed:2761388}.
Interaction partners:
Sequence:
MKKYLLGIGLILALIACKQNVSSLDEKNSVSVDLPGEMKVLVSKEKNKDGKYDLIATVDKLELKGTSDKNNGSGVLEGVKADKSKVKLTISDDLGQTTLEVFKEDGKTLVSKKVTSKDKSSTEEKFNEKGEVSEKIITRADGTRLEYTGIKSDGSGKAKEVLKGYVLEGTLTAEKTTLVVKEGTVTLSKNISKSGEVSVELNDTDSSAATKKTAAWNSGTSTLTITVNSKKTKDLVFTKENTITVQQYDSNGTKLEGSAVEITKLDEIKNALK
Protein: Beta-mannosyltransferase 3 (EC 2.4.1.-) (WRY family protein 9) (Q5A846)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Beta-mannosyltransferase involved in cell wall biosynthesis. Required for addition of the second beta-mannose residue to acid-stable fraction of cell wall phosphopeptidomannan, and in elongation of beta-mannose chains on the phosphopeptidomannan acid-labile fraction.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MFESDLSFYSALLILCCPISIVFFKKFPIKGYTGANKVSLFLQCLIAILNLNILYSFINSLTITLGHDGSSANTLTIDPITTTQQQGHVDYTPIKVSGYTFKNQVATKNLQCDSIVYDQDLDLQVSQAVDLNKPEDLKFFRDKLNELRSLNNIYDLFFQDNEDEVEESILERKWYKFCGSAVWLDKYGVYFMVNRIAYSKKGTRNNPTISVLAGQVFDKNWIELTGKKFPFSGLEFPTILPHYIDEGKEAEKVILGAEDPRVILHEYTNENGIRIQEPLIAFNALSTEVDWKRAMHIYRPLHDPHRIIRLSIENYAPREKEKNWAPFIDGNNLNFVYNFPLRILRCNINNGDCQKVSGPDFNDKSHENAGKLRGGTNLVEIPSQSLPKHLRSRKYWFGIARSHITDCGCVGELYRPHLILISRNKKSDQYELNYVSDLIDFNVNPEPWTPGKTTCSDGKSVLIPNSVAFIKDDYMSVTFSEADKTNKLINAKGWLTYITKMLEFTQERLKDESSDPVLESRLLSKCSTFLAQQYCALSKDTMGWDKLSR
Protein: Uncharacterized protein (Q57W46)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
METAAEPRLDPIEVDRSFVLSLFHGFCNSVPNDMRKKLVSEQTDVLQFMLAVRPRITPFAHRQLFSLRHPAVSWMSRRYFTALRTFLDENDLRNTEQGISCTSTPTRSGCEPADRSSRNSTLLPASLNPKSIKAKDLRAYNWNCIESCHKILIGESPFSALALESILSNEKLLDIVRRYWDRLTCPTTGADIYGAFDASGTVHPRNASSPVPELIQRANQMTPTQYTYLHMRFAQILLPPGALEAEIFDGIISDLRVDGKYPRRTAGLFPPASAVGPFLQDTVDILLDPERHIAKQMLPNLSDNVAMEGEMNSIRSALALPKTGASLLALPEITFAQFFYSIVELADNWTSTAHPNEYVAFLTELYCEAFGHDWDDEDPVLKKAFRPAERTPVPLPPDSRTSNEQLADQGDPAAHLLAEYATALSASKPPLYVFNKITGMSQDYRRGVTSAVRDLGLSRPRTGEEQADVTSVSTNEGLEVGGRLPRRQRRSEGSFIEADSEISGLEGLYEVGDVDDRELRGSQRARLPWRPHDRRWTGISRGGSLSSFPETYNTDMQTDSCGTSPVPESFGFHHRPREGRIPSLLDKRKSVTRAVCGEGGELTNRFESGESRESFELSMSRWESVGTEGSESRVDKGRAFPSSGNVTPESAGRRSPRKRKATAVAREGGSKSKRSNDAKASSGAASKARSVRSPGGGIHHITREGETEEFDEEAEISDSSSADDLHSGDERDEEGDRRGRGRKAGRARGHVKTLRWPEGSGHSETSEYDDEQSEEGLPAIYDEEGRRLHPPLHQQKHKGRSPRTSQGFAVGDADGSGGGVSAAYGYNARMLQGKGRWLSNTEMKCELGVSHSPGGGGATGLRPSDERSEGSDSDNEALAPLLLDQKRIEQKLRELEAEQQRLQASRGRGGRNIHELLEGTSDGVGRLIKFRLSSVERQRLTTEEVNQYRNVIINRLLAKGVNIPPESLTDDDVLNLMEDNLQPELVQRLMQLMEGYSEDLACSDLLDALLSDDAKIFTASGAMEASVLGALCKKSEHRPVETAYMRYLREKRERELREEIKAAKERYRATQNALREAQAKDATPTAVVPITEHIPTPPRAPAFLPALPLLSSARVGGPKRPTPKGPNAFYHEMDDFDTVVHMRPQPPSRGPMHLVPRHPLFPRRLPQAHRARFTLPSIHLPTQRYANEYYCEEDANGIRVRIHSKRRLRLFYREIRVDRPILGRAPLAPLTSIIGGTYHQLAALRVRCRRRRRFRLHMLRNLANERNLLPLPRYVPVKLFSLTTKTTLAEALRESLMCYINDKAYLDTLYGDMRR
Protein: Neuronal acetylcholine receptor subunit alpha-3 (P04757)
Organism: Rattus norvegicus (Rat)
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: Synaptic cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:19474315}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum {ECO:0000269|PubMed:19474315}. Golgi apparatus {ECO:0000269|PubMed:19474315}. Note=Interaction with UBXN2A/UBXD4 promotes translocation to the plasma membrane. {ECO:0000269|PubMed:19474315}.
Interaction partners:
- Neuronal acetylcholine receptor subunit beta-4
- Acetylcholine receptor subunit alpha
- Neuronal acetylcholine receptor subunit alpha-5
- Neuronal acetylcholine receptor subunit beta-3
- Neuronal acetylcholine receptor subunit alpha-9
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor subunit beta-2
- Tyrosine-protein kinase JAK2
- Acetylcholine receptor subunit delta
- Acetylcholine receptor subunit beta
Sequence:
MGVVLLPPPLSMLMLVLMLLPAASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFLNLLPRVMFMTRPTSGEGDTPKTRTFYGAELSNLNCFSRADSKSCKEGYPCQDGTCGYCHHRRVKISNFSANLTRSSSSESVNAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLMARDDT
Protein: Nif-specific regulatory protein (P27713)
Organism: Herbaspirillum seropedicae
Function: Required for activation of most nif operons, which are directly involved in nitrogen fixation.
Interaction partners:
Sequence:
MATILDDRSVNLELVTIYEISKILGSSLDLSKTLREVLNVLSAHLETKRVLLSLMQDSGELQLVSAIGLSYEEFQSGRYRVGEGITGKIFQTETPIVVRDLAQEPLFLARTSPRQSQDGEVISFVGVPIKAAREMLGVLCVFRDGQSPSRSVDHEVRLLTMVANLIGQTVRLYRSVAAERQQLQEEKRQLSRQLQGKYKLDNVIGISKAMQEVFAQVHQSAPSRSTMLLRGESGTGKEVIARAIHYLSPRKDGPFIKVNCAALSETLLESELFGHEKGAFTGAQGERKGRFELAHGGTLFLDEIGEISPAFQAKLLRVLQEREFERVGGSRSIKVDVRLVTATNRDLEKAVAKGEFRADLYYRINVVSIFIPPLRERREDIPYLVEHFLEKFRVENQRAMVAMSPQAMKVMMNCYWPGNVRELENCVERTATMMRGDLITEVHFSCQQNKCLTKVLHEPGQQQPVVVVPLERISAPYGAIFAEWDGQGQATGAAPPTSERERLIWAMEQCGWVQAKAARALNISPRQMGYALQKFNIEVKKF
Protein: Uncharacterized protein Rv1354c (P9WM13)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Multidomain regulatory protein Rv1364c
- Uncharacterized protein Rv1356c
- Uncharacterized protein Rv1355c
- HTH-type transcriptional repressor Rv1353c
- Probable transcriptional regulatory protein
- Uncharacterized protein Rv1357c
- Leucine--tRNA ligase
- Pre-mycofactocin glycosyltransferase
- Anti-sigma-F factor RsbW
- Probable transcriptional regulatory protein
Sequence:
MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS