wanglab/gogpt-training-data huggingface dataset:
Protein: Expressed protein (Q8W455)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At2g35170/T4C15.16
- Probable xyloglucan galactosyltransferase GT15
- Nucleolin-like protein
- Probable inositol transporter 3
- Probable leucine-rich repeat receptor-like protein kinase At2g33170
- RNA-binding KH domain-containing protein RCF3
- Poly [ADP-ribose] polymerase 1
Sequence:
MAKKGGATLAEDAPWRVSSGRPVPKISRSPVLSISQNPETDYAISVMKHPNPVGGGFAMEAVLESAGPECVVPGQVTPLRLLGVKVWPVEVDLKFLEPVGKELKMLGKFMDNAVELMNKSFIDR
Protein: ATP synthase subunit alpha (G8B7R3)
Organism: Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- ATP synthase subunit delta, mitochondrial
- ATP synthase subunit 5
- ATP synthase subunit gamma
- ATP synthase subunit beta
- ATP synthase subunit epsilon
- ATP synthase subunit d
- ATP synthase subunit 4
- Uncharacterized protein
- quinol--cytochrome-c reductase
- V-type proton ATPase proteolipid subunit
Sequence:
MLSARPVLRNAVRSAAVAARSSARVARPTLLTAQRFASAKAAPTEVSAILEERIKGVSDEANLNETGKVLSVGDGIARIYGLNNIQAEELVEFASGAKGMALNLEADQVGVVLFDSDRLVKEGETVKRSGEIVSVPVGPELLGRVVDGLGNPIDGKGPINASGHSRAQVKAPGILPRTSVHEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDAMLNQKRWNNGSDEKKKLYCVYVAVGQKRSTVAQLVQTLEQNDALKYSVIVAATASEAAPLQYIAPFTATAIGEWFRDNGKHALICFDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEANGGGSLTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLARGERLTQILKQKQYHPLAAEEQVPVIFAGVNGYLDDLPVNKVGEFEEAFVAHLKSDYSDLLKSIQEKGELSKEQLDQLHKITKDFVSNFN
Protein: Toucan, isoform E (Q0E8U3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGAHSSKEKLSRSYSERYIHSQMIERERFGSFGKRASKGLTKGAAKKRDVRNLSISPTDLGPPPKTQQTTKGQSTRSKSSATPTPTPTSIHKRLNGTLASTAAIATPIKGVATKSGATNKLQQSAKTKSTASIKSPAIVGVSEESLRSGVDQTELQELNNGQSATGCPTPPMARDSKRTSIGNELPCETEAKLKRCEDQQDPQASTTASPLPMINPQEQEASGQVKEATITTANEPNALSLPDEISNSVSSTTMLATPRVDIAAQYPVLKPFTENGELDCARLAKFFQDTQFERKEEQRQILGLSVMVQFMSKELDAVACKENKHQCARTKGTLEKTILLLQHTQKDCERLREDLEDKGLEWIQRQQEKEYLHRTELKQAEEKLMEVQLRAKLKFCELESQLRAKDEESKQAQEAYRMEVSHKLALKQEHLRTAEQKIQELQTRLQQVETEEQGHREELIRKENIHTARLAEANQREQDLIDRVKSLTKELNTLKANKEHNERDLRDRLALSQDEISVLRTSSQRRSPCTSLPDNASAELNRLTSEADSLRCVLELKQAEISALSKAKADLIHESEERLKLSNRVALLEAQNEMLRTELEAKTEKEKEIQQKMEELQKAYKYESIKRTRLTYDKEELQYHLKQRSLQLQSAESKLQDLSTGSHDNSLSSHSRCSLGRSGLEIAVTTSSPTSPVMKGMIERNDSVSWTLEIEDESFKGNTSKIVRRAGSLRSNNERCPIQRRQTLTSNGHSNGSATNGGSSPAHPNPLSQSMSATALLRSSSNSGESEGRPLSRARSKSMCIKASATSSAVCESSGQRKKPQDELSLADWPEDIPLCSSSPQAPGIEMRPRSSTMKLMSSEAKKFQEIQESAGEAMVSGANSEDESCSASSEDIMRSSSASSTASGGSLSKRPKQPPSRMSIEEALPCTPMEVSWSEDAADANGLA
Protein: Mlx interactor beta (Q9BKE5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MMLNKHEGYQRTSQMFPHQQHQLPQLHQQPYLQQSLCQNFQQLQYETGVGASASGSAEATADLLKAERESIHSGQFMVSHFEAEEAQDDLEDDGEVKMLDPEDPGLGKPGEPTNTCRDVQLYVPQTVAHFSAMDQEGDESSMSMVTSHLEIETSLTKLFKCMNLAYSQKLTSPKWNHFKGVRLRWKDKIRLNNVIWRCWHMQFIQKRRTPVCQFASPLDVDIHSNPQTVVLEGKYWKRHSAVIKAEYRKWRRNYRSKATGCLTYDSKSELDFLEWSPLNDRNLMPDDWTTDTLFSAINVPFPFPDSREIARGAGIADFIQPSLGPLQPNLDDIDISFSDLIPTTRLPPVPEEGTDAEMLKNDEYCLSAIVGAPHTLYCNDSIMDVVNSSNNGAVNVDASMLELNTPINNVSYGEVEQRFSVARQVQQSNNDSQLLGDSGSMSGRIHGGKHFGPASANDNNTNRCVINGRVAKSTQRPFRREPHNYDKAQPTMHQTNLYQQMLAEQQKNQQQQHVVVSSFQASQQQQLAQQQPFSAQATNAFNNQSFISSYADNYQHQQQLNVKVEPLHADVLSLLNDNAYNSIGYKPYPQFKKSASTGTFLNVPRQTQQQQSYLQQEPPQMQQSLPVGMGNQQILQLTRQQQVNNTQQQQHQSTVASLLQQQHQQQNHQQQQLQTAVSSATWVSPNTILPKEIYRSNSLPLNVSLNKLPDGRQLHHEQPFAVPKYHSKSKSRVRSNSMHQQHTSVVSAAGAGSSSLGAHSCSNLLVTQQMQQATSDPMLNSTLAQLLTSNSRLQTAVANSSSSNSPSVSAIATTNSNSNAPPVHYANVTSTFHESQDSPLSPTTSLKFQPRDTQRRAGHIHAEQKRRYNIKNGFDTLHALIPQLQLNPNAKLSKAAMLQKGADHIKQLRQERNVLKDKIEALRMERDELNNSLTHLHSILPANGAPVTRQGTEHVRQLYDIYVRYNTMNDWKFWILGLILEPLLASYTSTVSSASLDELRRTAFLWVDQHCSLIDLRPAVTNKLKYLSMHTDIVSEPPSTLQEEVAKALQNSSGQHPNLHGP
Protein: Apolipoprotein L, 6 (Apolipoprotein L6) (cDNA FLJ38562 fis, clone HCHON2004002, highly similar to Apolipoprotein-L6) (B3KTP4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRARGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT
Protein: Stretchin-MLCK (Q9NBC0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
YTCCATNDFGESLTHAQLRVYKHFKEAPLPSTFTQPIRDTYSLNENELVLDCRVRGQPRPEIQWIKGTEPIEASEKFKPSDQADGYAKLVIVNPTEKDSGIYWCVARNEGAENKISHQVDFKGRQHYSLEKTHGFFHRDPNKPHFLLPLGNQTVCNGGTVAISAEFMETSTPIEVKWLRDRRVVDGPNVKALADRGVYTLTIMNAGPEVEGTYTCRASNAFGR
Protein: Peroxiredoxin Q, chloroplastic (EC 1.11.1.24) (Thioredoxin peroxidase) (Thioredoxin-dependent peroxiredoxin Q) (Q9LU86)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Involved in the photosystem II protection against hydrogen peroxide.
Subcellular location: Plastid, chloroplast thylakoid lumen {ECO:0000269|PubMed:16507087}.
Interaction partners:
- Peroxiredoxin-2E, chloroplastic
- NADPH-dependent thioredoxin reductase 3
- Peroxiredoxin-2F, mitochondrial
- Thioredoxin F1, chloroplastic
- Thioredoxin M4, chloroplastic
- Thioredoxin-like protein CDSP32, chloroplastic
- Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic
- Peroxiredoxin-2B
- Peroxiredoxin-2C
- L-ascorbate peroxidase T, chloroplastic
Sequence:
MAASSSSFTLCNHTTLRTLPLRKTLVTKTQFSVPTKSSESNFFGSTLTHSSYISPVSSSSLKGLIFAKVNKGQAAPDFTLKDQNGKPVSLKKYKGKPVVLYFYPADETPGCTKQACAFRDSYEKFKKAGAEVIGISGDDSASHKAFASKYKLPYTLLSDEGNKVRKDWGVPGDLFGALPGRQTYVLDKNGVVQLIYNNQFQPEKHIDETLKFLKAA
Protein: Protein virB5 (P17795)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Function: VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
Interaction partners:
Sequence:
MKIMQLVAAAMAVSLLSVGPARAQFVVSDPATEAETLATALETAANLEQTITMVAMLTSAYGVTGLLTSLNQKNQYPSTRDLDTEMFSPRMPMSTTARAITTDTDRAVVGGDAEADLLRSQITGSANSAGIAADNLETMDKRLTANAETSTQLSRSRNIMQATVTNGLLLKQIHDAMIQNVQATSLLTMTTAQAGLHEAEEAAAQRKEHQKTAVIFGAVP
Protein: Insulin-like growth factor 1 (Insulin-like growth factor I) (Somatomedin) (F2X2F2)
Organism: Bos taurus (Bovine)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU000406}.
Interaction partners:
Sequence:
MVTPTQVKMPITSSSHLFYLALCLLAFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKAQKEVHLKNTSRGSAGNKNYRM
Protein: Ig superfamily receptor LNIR (Nectin 4) (K4PZ75)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, adherens junction {ECO:0000256|ARBA:ARBA00004536}. Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV
Protein: Cyclopropane mycolic acid synthase 2 (CMAS-2) (EC 2.1.1.79) (Cyclopropane-fatty-acyl-phospholipid synthase) (CFA synthase) (Cyclopropane fatty acid synthase) (Mycolic acid methyltransferase) (MA-MT) (S-adenosylmethionine-dependent methyltransferase) (AdoMet-MT) (SAM-MT) (P9WPB5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. In the absence of MmaA2, CmaA2 has a non-specific cis-cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence.
Subcellular location: Cytoplasm.
Interaction partners:
- UPF0336 protein Rv0504c
- Phosphoserine phosphatase SerB1
Sequence:
MTSQGDTTSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERPDMTLEEAQYAKRKLALDKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHDKAMFDEVDSPRRKEVRIQGWEEFDEPVDRIVSLGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDGRMLLHTITIPDKEEAQELGLTSPMSLLRFIKFILTEIFPGGRLPRISQVDYYSSNAGWKVERYHRIGANYVPTLNAWADALQAHKDEAIALKGQETYDIYMHYLRGCSDLFRDKYTDVCQFTLVK
Protein: Kinesin-related protein 9 (Kinesin family member 9) (Q555I8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity).
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000250}.
Interaction partners:
- Sun domain-containing protein 1
- Tubulin alpha chain
- Kinesin-related protein 8
Sequence:
MDNNNNNFSTPKQPTINSTTGGQLRSRSNSSPSTSSISTPRNGSTTATTSSITNSIGKGSLVFSTMENAKKTLNMDSLSTPMSQSSKKRLSMNSSLLPPSSIPLPPSQQLSAKKDPSKRHSSFISTTTTTSLGSRPSTPQPNHTTNNNNNNNNGSNGNNVTSTNISSMLESNNSEILSQNQKVTLSTSSNTAFSSLPSSTNNGNNPLSNSGGGNGNHHLVNSNSSTSTPSPTMFISTTSPPPELSLMEGFNQHNLTTTTTTTTTTTNNTLNTSNGINSNSLSPSSHLNNGSNNNNNNNHLNLNNRSSSPSPTPSSSSISGRRTPIQNFNSVGGVNITSKTQPLFSDREESIQAVCRFRPETAAEQTLGPSEKQLTIGTDQTTIHITPTSSSSSSMAQAFRFSKVYQPNTTQESFYNEVGKPLIDNIVNGYNVGIIAYGQTGAGKTFSLGFSGGEGNDSYNSYCNRSEFYNNSHYLYGSQQQQQQQQLLPSSWGIMPRIIKDLFIKQDEQQSMNTPQRIKFTTKISYLEVYKEKVYDLLSEGGVNDIEIRMADGGFIVPDAVQSSIQTFTDFLTHLQHIEKNRKIAETKKNMASSRSHAIFIVSLLKEDLENKMTVTSLLYLVDLAGSESASKIDGTTSKIEETKSINKSLYALGGVIEDMSKNSKHVRYRDSKLTQLLQQCFGGNSKTCLIVNCSSSNHESVIRETIQSLNFGQRAQSVKNKPLQNVEESHSELKAKLRELNKDIETYKKFIEKISINSGVIPPSSVATYITQLQNACEELKKKNDRLQEDIINLEEENSDLPKKFNVLNKNNVSQIEILTQELELSKQINQEQLLKIEQYSQKYQATNEEIQKSFNHRQQLVNDLHDSNEKSKQLELKLKDALLNSKSESDEIRLKLTKALEESTDKDQRINTLESNKQKWKSKCNEVVRQSKELQDRLNILQSTYSNSVDSLSNSSLNNNNNESLEEIKKLKLNISSLTNQHIEREKSLQKEIDLARSKHTEQTLILKNLKTQIDTLTNKLEIQFPTIVNNNQQQQQSTQSSSSSSIESNLIISMNTIEVLFEKICKNQEQTNTIISTNVESIMGKLVEIDENEEFIRKEKDRERERAENLKNTLEDAQSNFLKQQEEIKQFIETQLKNKNNINNNNNIKNNNNNNKLKSKKVGSSSSSSSNIGSSICINILFFLIILVILFFLMVAVGLTIQNQDYNSQYRSSYFFKTT
Protein: Vascular endothelial growth factor C (VEGF-C) (Flt4 ligand) (Flt4-L) (Vascular endothelial growth factor-related protein) (VRP) (P49767)
Organism: Homo sapiens (Human)
Function: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors.
Subcellular location: Secreted {ECO:0000269|PubMed:9233800}.
Interaction partners:
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- Vascular endothelial growth factor receptor 1
- Neuropilin-2
- Vascular endothelial growth factor D
- Vascular endothelial growth factor B
- Angiopoietin-1 receptor
- Collagen and calcium-binding EGF domain-containing protein 1
- Lymphatic vessel endothelial hyaluronic acid receptor 1
- Neuropilin-1
Sequence:
MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATAYASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGFSYSEEVCRCVPSYWKRPQMS
Protein: Frataxin, mitochondrial (Fxn) (EC 1.16.3.1) (Q9TY03)
Organism: Caenorhabditis elegans
Function: Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q16595}.
Interaction partners:
- cysteine desulfurase
- NIF system FeS cluster assembly NifU N-terminal domain-containing protein
- Complex 1 LYR protein domain-containing protein
- 2O16
- Selenocysteine lyase
- Mitoferrin
- J domain-containing protein
- 2Fe-2S ferredoxin-type domain-containing protein
- NFU1 iron-sulfur cluster scaffold homolog
- Cytoplasmic aconitate hydratase
Sequence:
MLSTILRNNFVRRSFSSRIFSQNEYETAADSTLERLSDYFDQIADSFPVSEQFDVSHAMGVLTVNVSKSVGTYVINKQSPNKQIWLSSPMSGPKRYDLEEEGKWTYAHDGEQLDSLLNREFRKILADDRIDFSRHV
Protein: Interferon-induced protein 44-like [Cleaved into: Minor histocompatibility antigen HA-28 (HLA-HA28) (IFL8)] (Q9BDB7)
Organism: Mus musculus (Mouse)
Function: Type I interferon-stimulated gene (ISG) that plays a critical role in antiviral and antibacterial activity. During bacterial infection, promotes macrophage differentiation and facilitates inflammatory cytokine secretion (By similarity). Plays a role in the control of respiratory syncycial virus/RSV infection, reducing the ability of the virus to replicate. Acts as a feedback regulator of IFN responses by negatively regulating IKBKB kinase activity through interaction with FKBP5 (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11021531}.
Interaction partners:
- S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
- Ubiquitin-like protein ISG15
- Interferon-induced protein 44
- Interferon-induced protein with tetratricopeptide repeats 3
- Receptor-transporting protein 4
Sequence:
MKVTARLTWIEEKILEKLLGNASLTLLYQSSAHKNCVSEMTQKYSLQGSTMTVFHLEKDVVVGVFILENFPRLVSEKPCTCAWFSLKRNNSSGISALFLNTKVIVDSEELIIFSLDGLSLSVTPLRGFTLALNDTVMNGLELNLGHGFLPVECEIFRVDGIKKNPSFIKKMVTAEQHRGKLLSALRAYKPYKDLVSEVRILLVGPVGSGKSSFFNSVKSAFQGHLTRQAIVGSDESSITKQYRVYSIKDGKSGETLPFMLCDSMGLEEGEEAGLCIDDIPHILQGCVPDRYQFNPCEPMKPKHSPHAASPPLKDRIHCVAFVLHINSVNTLSDKMVAKLKKIRKDVVDCGIGYVALLTNVEEYDEVLDDSFANMTETVTSLSQVQNVQKWLNIPIANILMVSNYASERRLEPMKDILVFAALRQMLRAADDALEDLPLEDTGNLAPF
Protein: GID complex substrate-recognition subunit 4 (Glucose-induced degradation protein 4) (Q10079)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P38263}; Peripheral membrane protein {ECO:0000250|UniProtKB:P38263}. Note=Colocalizes with FBPase-containing vesicles. {ECO:0000250|UniProtKB:P38263}.
Interaction partners:
- GID complex subunit 1
- GID complex subunit 8
- GID complex subunit 7
- E3 ubiquitin-protein ligase gid2
- GID complex subunit 9
- Fructose-1,6-bisphosphatase
- SPRY domain-containing protein C285.10c
- GID complex subunit 5
Sequence:
MKGCSFLRNGAKFQGKQKGVSSSTLEVHVTILHVNLAKSMLCGFIHVSYTSPNNTSLTTYFEAEIIGNRFTFETKWPEWGASEEIDNRHWKRLGALKSNGKDIPLRLIQPYDPLSRETVYMRWKELAMLDKTVDYQNHNQSFPFGISYEGFYYISFSQSTGKIKGYYYHHSEPEKVLFLELNPIIDRTFPVIEFQ
Protein: Zinc finger protein SNAI2 (Protein snail homolog 2) (Q91051)
Organism: Gallus sp
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPRSFLVKKHFNSSKKPNYSELDTHTVIISPYLYESYPVPIIPQPEILSSVAYNPITVWTTTGLLPSPLPNDLSPLSGYPSSLGRVSPPPPSDTSSKDHSGSESPISDEEERIQSKLSDPHAIEAEKFQCGLCNKTYSTFSGLAKHKQLHCDAQSRKSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVNKYQCKNCSKTFSRMSLLHKHEESGCCVAH
Protein: Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5) (O95136)
Organism: Homo sapiens (Human)
Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Receptor for the chemokine-like protein FAM19A5. Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:25274307}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Guanine nucleotide-binding protein subunit alpha-13
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-12
- Sphingosine kinase 1
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Sphingosine kinase 2
- Apolipoprotein M
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
Protein: Ovo-like zinc finger 1a (Transcription factor Ovo-like 1a) (F8W4G4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPRAFLVKKTGNSPGKRNWSDLPDHERGDIYIPVSMSPFAYREETEASPAEVPLCLSKRKDRNMYTHSQMYTNDPGAVVPVAELPSCTALGQSPETEHIRSTQNNTYVRTKIKVTTGELPTEAPPVVPSVTTSPPVSIATHCSPPVTKPLMVQSSGATYVCQVCQKVFQFQRMLNRHLKCHSEQKRHLCDFCGKGFNDTFDLKRHVRTHTGVRPYKCELCDKAFTQRCSLESHMKKIHGVTQQYAYKERRSKLYVCEECGHTASTQDALLRHLHTEHPNSAFLRAKGARRHSPSLNGTKDDTSQPGSPLSLNSDDNAES
Protein: Sperm acrosome membrane-associated protein 1 (Sperm acrosomal membrane-associated protein 32) (Q9HBV2)
Organism: Homo sapiens (Human)
Function: Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis (By similarity). Important for male fertility.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane {ECO:0000269|PubMed:11870081}; Single-pass type I membrane protein {ECO:0000305}. Note=Primarily found in the equatorial segment of the acrosome (PubMed:11870081). The tyrosine phosphorylated protein localizes to a smaller region within the equatorial segment (By similarity). Also expressed weakly in the principal segment (PubMed:11870081). {ECO:0000250|UniProtKB:D5K8A9, ECO:0000269|PubMed:11870081}.
Interaction partners:
- Zona pellucida-binding protein 1
- Izumo sperm-egg fusion protein 1
- Probable C-mannosyltransferase DPY19L2
- Serine-rich single-pass membrane protein 1
- Sperm acrosome membrane-associated protein 3
Sequence:
MSPRGTGCSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYAPPETEDVSNRNVVKEVEFGMCTVTCGIGVREVILTNGCPGGESKCVVRVEECRGPTDCGWGKPISESLESVRLACIHTSPLNRFKYMWKLLRQDQQSIILVNDSAILEVRKESHPLAFECDTLDNNEIVATIKFTVYTSSELQMRRSSLPATDAALIFVLTIGVIICVFIIFLLIFIIINWAAVKAFWGAKASTPEVQSEQSSVRYKDSTSLDQLPTEMPGEDDALSEWNE
Protein: Histone-lysine N-methyltransferase (EC 2.1.1.355) (A0A8I5ZJE7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR009343}.
Interaction partners:
Sequence:
MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGVSKKNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNLKCVRILKQFHKDLERELVRRHRRSKPPRHLDPNLANYLVQKAKQRRALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLHKFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYNLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEVPPGCYMLGQ
Protein: Calcium/calmodulin-dependent protein kinase II inhibitor 2 (CaM-KII inhibitory protein) (CaM-KIIN) (Q96S95)
Organism: Homo sapiens (Human)
Function: Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2 (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9Z2N6}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9Z2N6}. Synapse {ECO:0000250|UniProtKB:Q78WH7}. Note=Excluded from nucleus when coexpressed with activated CAMK2. {ECO:0000250|UniProtKB:Q9Z2N6}.
Interaction partners:
- Calcium/calmodulin-dependent protein kinase type II subunit beta
- Calcium/calmodulin-dependent protein kinase type II subunit alpha
Sequence:
MSEILPYSEDKMGRFGADPEGSDLSFSCRLQDTNSFFAGNQAKRPPKLGQIGRAKRVVIEDDRIDDVLKGMGEKPPSGV
Protein: Transporter, monovalent cation:proton antiporter-2 (CPA2) family (A0A0H2UP25)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFLPNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGLAHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLVAFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIASELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHTVTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYYAYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTLVSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYHGRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNIEQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAELYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNIDEMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVRRN
Protein: ACT domain-containing protein ACR7 (Protein ACT DOMAIN REPEATS 7) (Q8LJW1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May bind amino acids.
Interaction partners:
- At5g60630
- Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MOK16
- Probable receptor-like protein kinase At1g11050
- EEIG1/EHBP1 protein amino-terminal domain protein
- ACT domain-containing protein ACR11
- Late embryogenesis abundant
- Probable leucine-rich repeat receptor-like protein kinase At5g49770
- F25P12.91 protein
- Probable cysteine protease RD21C
- CHP-rich zinc finger protein
Sequence:
MELSDCSNEYEKLVVRMNMPRVVIDNGVCPNSTVVKIDSARSPGILLESVQLLTDMNLWIKKAYISSDGKWNMDVFHVSDLNGDKLTDENLIRYIEKSIETSHYCKTEGYTGLTALELTGTDRVGLLSEVFAVLADLECDVVEAKAWTHNGRIASMIYVKDGNSGTPIDGDSDRVQRVEGQLRNLLKADDGYQNDTRTCVSYGGNTHMERRLHQRMFMDRDYEKKFDIEKSPIVSVQNLPKRGYSVVNLQCKDRMKLLFDVVCTLTDMAYIVFHAAIRTVGETAFLEFYVRHSDGHPVSSEPERQRLIQCLQAAIERRTVKGVRLELCTADRPGLLAEVTRILRENGLNIARAEISTKDSIARNVFYVTDANGNLIDPEIIKSIREKIGIDDLSVKEPFPISCREAVEKEQHIEPQDHQGRYGGGTVLVSLGSLVMRNLYHLGLIKSYF