wanglab/gogpt-training-data huggingface dataset:
Protein: Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (A0A0B4KF06)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Tyrosine--tRNA ligase
- Cysteine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase
- Probable arginine--tRNA ligase, cytoplasmic
- Elongation factor 1-gamma
- Alanine--tRNA ligase, cytoplasmic
- Probable glutamine--tRNA ligase
- histidine--tRNA ligase
- serine--tRNA ligase
Sequence:
MPEAEQQNDANAPAGAGGDPPKTAKQLEKERLKAEKLAKLQAKLDKKAAAAPAAGEKKEKPEKRTKEVKEAAVYTAQTAPGEKKDLSGALPDAYSPRYVEAQWYSWWEKEGFFTPEYGRASIDAPNPNGKFVMIIPPPNVTGSLHLGHALTNAIEDAITRYHRMKGRTTLWVPGCDHAGIATQVVVEKLLWRDEKLSRHDLGREKFIERIWDWRREKGGRIYEQLKSLGSSYDWTRVAFTMDPKLCRAVTEAFVRLHEEGSIYRSSRLVNWSCTLRSAISDIEVDKVEIPGRTFLSIPGYEDKVEFGVLIKFAYKVEGSDEEIIVATTRIETMLGDTAVAVHPQDDRYKHLHGKFVVHPFSTRRLPIVCDEFVDMAFGTGAVKITPAHDPNDYEVGKRCNLPFITIFNDDGYIIGDYGEFTGMKRFECRKKILEKLKALNLYRETLNNPMVVPICSRSKDVVEPLIKPQWYVSCSDMAASATEAVRSGELKIIPEHHTKTWYHWMDGIRDWCVSRQLWWGHRIPAYHVSFTDPSLQTGSSAHGSVNDDEQYWIVARSEAEALTKAAERFGVDASKIVLKQDEDVLDTWFSSGIFPFSVFGWPDQTKDLQTFYPTSLLETGHDILFFWVARMVFFGQKLLGKLPFKEVYLHPMVRDAHGRKMSKSLGNVIDPMDVIRGITLEGLHAQLVGSNLDPREIEKAKAGQKQDYPQGIPECGSDALRFALCAYITQARDINLDINRVLGYRFFCNKLWNATKFALLYFTGSEKFDTELSASAAINQMDAWILSRLAAAIEACNTGFESYDFAAATSACYAFWLYDLCDVYLECLKPIFQSGSEEQQTAARRTLYVCLDYGLRLLSPFMPFITEELYQRLPRANPAPSICVASYPSNTSWRSTKIESDVEFVQKAARIIRSARSDYNLPNKVKTEVYIVCTDSVPSEILKRYASDLATISYCSNVVFDSPAPQGCAILTVTGQCEVHLLLKGLVEADKEIAKLQKKSDQLVQTVGKLTQAIQAADYATKVPAEVQEANETKLCESRAEIERIAAAIETLKLM
Protein: Reduction in Cnn dots 1, isoform C (EC 3.-.-.-) (A1Z9L2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEHSYMRDTPVRSDVHNGLTPARNILVRHPPQCPSCHTYPPQHEELSEIQQAHVPPYDEVVAKEAMNECARIAKYVKNNNSDEQDWVARVNKFNWTPMQEMVFEKVCSILDQDQLARLANDKRQHEPIHRRISSDKSASRFRKLLASVAWESRITQWIHALLMEHLSPSYMASYLEILQTLKTKLPTLVDKMLFGRPLNNSQELLAPVMKKRWEPNIMPKSRQLTHNAIMVVLPNMPTTGTVSDRMQKWYQALSTITQVVQISLPNTNNRIGNQNLDHVAETIVSITRVKINELRTENPSRGIILVGFNAGAALALQVALSESVACVVCMGFAYNTIRGPRGTPDDRMLDIKAPILFVIGQNSARTSQEEMEGLRERMQSESSLVVVGSADDALRVPKSKRRIEGVTQSMVDYMVVEEIFEFVNRTLSNPPGPRMPTCLMHQQGYQRLPKQSPHILADGNANKAVQQMRKRKMDGGLDDSMGQPSKTKFVPHNDAQDYGDAQTTAGGSASLPKVITPGVLGKQLPPVNLAAGTKIKMIPSSQFVQIKSLPSQSKLINYTLNKPSVGTSSTANIGSVVKTLPCSSVSGQQIITLKTPSGQTQQFATAATSTGAAGSSTSTGTGQKKYTVFKNANGMTMLHLTKSVPTTGSSSGSANMDLSNIIDMPIVFADNEGNIPEHQQADKDIKPAPIRSANKSPLIISQKIIKEANKPSGMVTSGSITAVSKPGNIVLNKGLQQLLNSSPGGTLATQNKVVYLNRSTIKPMGNVAPGTHRVPIRIVSTPNTGGAVTTTASSSPIMVDPATGSKVAKTVNVQTIKPTGSVLAQGTIRQAGNVGTKSYLQMINTAPGASKTVAGDGKGSVRNIYFKSATGLKQLPVQMLGNRIPGGAVISSTASASSGSPGLRRVVNIGPVSKVTATSTTSSSIAATLTHNKM
Protein: T-cell surface glycoprotein CD5 (Lymphocyte antigen T1/Leu-1) (CD antigen CD5) (P06127)
Organism: Homo sapiens (Human)
Function: May act as a receptor in regulating T-cell proliferation.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P13379}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P13379}.
Interaction partners:
- T-cell surface glycoprotein CD4
- T-cell surface antigen CD2
- B-cell differentiation antigen CD72
- T-cell differentiation antigen CD6
- T-cell antigen CD7
- T-cell surface glycoprotein CD8 alpha chain
- Tyrosine-protein kinase Lck
- Immunoglobulin lambda-like polypeptide 5
- B-lymphocyte antigen CD19
- Leukosialin
Sequence:
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPDNSSDSDYDLHGAQRL
Protein: Serine/threonine-protein kinase Genghis Khan (EC 2.7.11.1) (Q9W1B0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as a downstream effector for the regulation of actin polymerization by Cdc42.
Interaction partners:
- Cdc42 homolog
- Ras-like GTP-binding protein Rho1
- GTPase-activating protein CdGAPr
Sequence:
MEYESSEISDITTGSCKKRLTFLKCILSDTTSDQKWAAEFGEDTEGHQFSLDYLLDTFIVLYDECSNSSLRREKGVSDFLKLSKPFVHIVRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFDVDDNDVRLTDSIPPSANPAFSGFHLPFIGFTFSLTSSSTLDSKKNQSSGFGDDTLDTISSPQLAILPSNNSETPVDSVQLKALNDQLAALKQEKAELSKQHNEVFERLKTQDSELQDAISQRNIAMMEYSEVTEKLSELRNQKQKLSRQVRDKEEELDGAMQKNDSLRNELRKSDKTRRELELHIEDAVIEAAKEKKLREHAEDCCRQLQMELRKGSSSVETTMPLSISSEMSSYEIERLELQFSEKLSHQQTRHNMELEALREQFSELENANLALTKELQQTQERLKYTQMESITDSAETLLELKKQHDLEKSSWFEEKQRLSSEVNLKSKSLKELQAEDDEIFKELRMKREAITLWERQMAEIIQWVSDEKDARGYLQALATKMTEELEYLKHVGTFNNNGVDNKNWRNRRSQKLDKMELLNLQSALQREIQAKNMISDELSQTRSDLISTQKEVRDYKKRYDSILHDFQKKETELRDLQKGGLEYSESFLNKSTHHGLSSAFFRDMSKNSEIIDSAESFGNESGDNFTPNFFQSGNSGMLFNYEPKYAGKNNKDHSSMKEASVSDLSREESDQLVKESQKKVPGNTAIHQFLVRTFSSPTKCNHCTSLMVGLTRQGVVCEICGFACHTICCQKVPTTCPVPMDQTKRPLGIDPTRGIGTAYEGYVKVPKSGVIKRGWIRQFVVVCDFKLFLYDISPDRCALPSVSVSQVLDMRDPEFSVGSVRESDVIHAAKKDVPCIFKIKTALIDGGLSLNTLMLADNESEKSKWVIALGELHRILKRNSLPNTAIFKVNEILDNTLSLIRNALCSVIIYPNQILLGTEDGLFYINLDQYEIARIGESKKILQLWYIEEEQILVILCGKQRNLRLLPIRALEASDVEWIKVVESKNCISACTGIIRRFPNIVYSFIIALKRPNNHTQIVVYEINRTRTRHQKTCEFTIGYMAQHLQILSDMRLVVAHQSGFTAYFLRGEATAMSLVHPENQLCAFLNYSGVDAVRVIEILCPSGGNFGEYLLVFQTLAIYVDLQGRKSRDREIMYPAFPTYITFCDGHLLVFSDTHLDIFNTQTAEWVQSIGLKQSLPLNNLGNVVLSSVNDTPLIVYLSNIHTKGLLQYRDGNRKGLPSIKRRFSIREINKTIKSDRRSKMISAPTNFNHISHMGPGDGIQNQRLLDLPTTLETADQACSPIIHSLSCIPQSRKSNFLEQVDANSDDYGNDNIISRTPSPMASSFMDGLSNND
Protein: Leucine-rich repeat-containing 4.1 (Leucine-rich repeat-containing protein 4) (E9QDQ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Leucine-rich repeat-containing 4.2.
- Proline-rich transmembrane protein 4
- Transmembrane protein 53
- Proline-rich transmembrane protein 4.
- Low-density lipoprotein receptor-related protein 11
- N
- Uncharacterized protein LOC322379 precursor
- Odorant receptor
- RNA-binding motif protein 4.3
- Immediate early response gene 5-like protein
Sequence:
MCHIMSLLGRVAVRRARKAALLCVLFLMVQACVEVVAAAGPQGCPTDCSCNNQLSKVVCTRRGLTRVPPGIPSTTRHLNLMENAIESVQVDSFRNLHHLEVLQLGRNAIRQIEVGAFSGLTNLNTLELFDNRLTVVPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELRKLEYISDGAFEGLVNLKYLNLGMCNIRGEMPNFTPLVGLEELEISENLFPEIKPGSFRGLSSLKKLWIMNSQIGLIERNAFDDLASLVELNLAHNNLSSLPHDLYTPLKYLVELHLHHNPWNCGCDSLWLARWLREYIPTNSTCCGRCHSPAHMRGRQLVELDRGDTGAMQCSAPFIADAPRDLNISAERVAELKCRTAAMSAVRWLLPNGTILTHASSHPRLTVLNDGTLNFSNVLAGDTGMYTCMVSNAAGNSNASAYLNVSAAELNTSNLSYFTTVTVEVLSPTSEMPKPKTTTTTAGASTTTTASPSVFQPVFISTPTVLLQSTDTPPSRPSVIPGSKVTTGKPPNPASTSLDEVMKTTKIIIGCFVAVTLLAAIMLIVFYKLRKRHQQRSTVASARTVEIIPVDEELPPSASAANIADEGQLSLPEIRNHNSIYKADYTHKFDYGYKPKLEYSTHKPKQDFSIHQPKSDYNTYKPKADYMYQPTLEYSSQKLTDYSHKSLPDYHVHKKPEQSPYKHGYGTHKPDYKSHTPKPDFSPFKTEYGVPKSKTDYSMPKPKPDYSPFKTDSFFKPDYIAFKAEYSPLKAEYVSRDFSPHKYKKDYSPHNVDYSPHKMDYSTMKPKYNTYKPPGHSAKWTESNSIGNSLPRTMPSAITASPEALVIKTHTKEKVQETQI
Protein: Zinc finger FYVE domain-containing protein (E1C6T3)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR037289}. Early endosome membrane {ECO:0000256|PIRNR:PIRNR037289}.
Interaction partners:
- Mothers against decapentaplegic homolog
- Mothers against decapentaplegic homolog 3
- Mothers against decapentaplegic homolog
- N-acetyltransferase 9
- Uncharacterized protein.
- Synaptic vesicle 2-related protein
- Ubiquinone biosynthesis protein
Sequence:
MENYFQAEAYNLDKVLDEFEQNEDAAASPTLLGAKWNQILDPPSRRLSYNPTVADVNEATTPNECQQRLKSFSSSHSVTTPTGGEDHCANGKDFNLSPEIPVMWIDDQAAADDQLIKRNSNRDDQCNTVESGEKKCGSIACLPEEKNVLVVAVMHNCDRRTLQSGDLLDCKNYNSQSLKDTISFTLDNENQQSDEFSVTVNGSMEKDTDTEKQVNWLRTEDDSRSNLFNASSETLTVACPSSCLKDDFNMSKDSWLSEATAAGINTVTLCKRPVDGIVKMQENCLSVENFSSKAIPQRTDVEVKNFSGSSNGSLGEETTQQIRSRLSGLEETCQSNAAGSSNYKECVAEHFTSEDGSAVESEVIECDKNLSTSEVLSMEECYPESQEMTNWELSRLNEINNKQTVEENERLLQTKQPDEACSSSKEGGEGKMESGIDLKGTGTDELEGSSLSDAMGTSTASSLSNGCDSYGMQNPVVPHVPKTLPSKEDSVTEEKEIEESKSECYANVYEQRGNETIEGSGLILNSAGDQVKKNYIHNLCSQVPSLQGQTSPKPVTNLQSVSVPFGGARPKQPTNLKLQIPKPLSDHLQNDLVPPNCGGNSKNKNVFVKTQLGDNLTADVFPGEASLNAPVTDTNGEHLEEYESGISSSPCLAVAPDSPDNDLRAGQFGAPARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCAACCSLKCKLLYMDRKEARVCVICHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPLQQAQASGALSSPPPTVMVPVGVLKHPGAEVAQPREQRRVWFADGILPNGEVADAAKLTVAGTTSTGTLAVSHDPTKPVTNNALSAETDNASVFSGSITQVGSPVGSAMNLIPEDGLPPILISTGVKGDYAVEERPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVGNLGHSFFSQSFLGSKEHGGFLYVAATYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKVDAEDPQEHVHIQWVEDDKNFSKGVVSPIDGKSMESITSVKIFHGSEYKANGKVIRWTEVFFLENDEQHSGLSDPADHSRLTENVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVIMELIFYILENIS
Protein: Prolactin family 8, subfamily a, member 2 (A0A286YDW1)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
XTLVSRMYRRDEEVLRARNHCHSNVTNPPAHGPEHENLKVYPKVTFWEKSIIWEYLPGLRSTDTSKKFLAMFNLSHCLRVDIFFIKYHLSALMCRITGQDC
Protein: PAK4-inhibitor inka1 (Induced in neural crest by AP2-alpha protein 1) (zinca1) (F1QR98)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Inhibitor of the serine/threonine-protein kinase pak4/pak5 (By similarity). Acts by binding pak4/pak5 in a substrate-like manner, inhibiting the protein kinase activity (By similarity). Required for the proper migration of neural crest cells during embryonic development, probably by inhibiting pak4/pak5.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96EL1}. Cytoplasm {ECO:0000250|UniProtKB:Q96EL1}.
Interaction partners:
- Eukaryotic translation initiation factor 4, gamma 2a.
- Mix-type homeobox gene 2
- Si:ch211-243g18.2
- non-specific serine/threonine protein kinase
- Sulfite oxidase, mitochondrial
Sequence:
MLCLQESGDCLRDQMRYMMRSLQDLKHLRRSCVAPPVGPPVRLRACKQLIAQRERRARLRISDASEASSYDSACCLSSSLEEEESASDPSAVSSPSSERSLEFDSGYSEASWQDEGVVLRRTKNIRVSSTACLRTNQLSNTRARPKSTSDACLESWTSFETASDPEDWTTSLLTRGRNRQPLVLGDNSFADLIHNWMDLPECPEQTELKHSSGRSFAKDFLVNIKRRIAGFSRSADGRRKSSDVTKLSKSIVPTKRLSCQIDVQHKMPFFYKSHTGLNELDTDYYQFSALMKSGSRTPIVCNDIIGYI
Protein: SEC7 domain-containing protein (Q381I9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ADP-ribosylation factor-like protein, putative
Sequence:
MEALLRSLDSLLALVSRGDGGSFVIDPEFKQALKQAQSSVGRWRGGAWKSERIRFVTDSVMSSVLGALYIKKTRVTEAALPLLQRMIHNNCIQYTTSIVLYRANGSSSVLSCGAAMFEALGDVLARITDAGLQLTSVEILHDLVSDDSFPSFTGKCVTRCIQTCCRVALLGASEGARGISRDLLPLCVLRVTRTFLESAPTDSRSCTFTSLTPLDDYVHDVEPDSKHLPISVENNTDPFVEASLGETTGDERAAQSLSHNSECELFAETTFSSFDYFRSTLNGQIIGSALSSMKMGRFPDAMKDLLLLIKHTCSLGARTVSGSGSTGEGGPEARARQLALDMLEAVFQALPMANCCAEHHCATWLSLVITATKYDLTRCLARNLTAVAPASFFASAVRIISLLLQKCHYHLARELHTVLAVMLFPLALSRYSSFSQKHAVVDMVRELLSVPHLCVSLFINYDCNPTFDAGGKYGGMLELMVNFVAEMTFTHLIEPDWLSDDQQQLLRSGCASAIHNLVHSLQRWIAEDPDDYSHQQTREVVGQVLSRLPGDTVSDNRWYDVYRNYSERDVKDGHRVSERVTGNNMPVSPIVTDESLFEQQGVERRWSVGYHWKHIHYLLHSKRTAQLAVGLINKGQWRQAMSFLKERDYIPAEGEEGWSAFALFLKTYEGVERGALCGIFERVLKDKDCDRILREYLQHFSYRNVPIDIALRDTTCEFMSWDRPTFEAQVWVVIQQRFGEVYAAQNPRSISPDDANAMAGVLLFLHTSLHNANVRSSRMTMKDFVRNGNECVAVPFPEDVMCEMYTRVARSKWELDRFQRTPRQAEMEFSSPGLARMLDIYNQQRQQHVLSSEQLAPADAVGQTVDAAGLSHSGSGTRDASLENFVGSSGHSDSSLLDASMLPYTEELETFKSREPYHQRYAELALQCLQRLEREHRVLCGDRGGVQPYAIPHYAQHVRPMLLSLYPQIAATIYKGLRVLEVQPILRLLHDTYSMLDDLVAAFAVNLTGMHVAVEKRIQYYMLRGGTRHLPPPTRATFALPLMNLV
Protein: Myosuppressin receptor 1, isoform B (M9PEC0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- RYamide receptor
Sequence:
MASGNNETEPLYCGSGMDNFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTLLFRPKFLDKWLPVAQDEMAAARAERSAVAPVLEKGRQQPQVVMASTTTNITQVTNLXHRRSRGRRTLLSRLLSVLKRGRRRSSGEGGGVGGGGAPLAGNDAVEPAFQAIVVVVDKVSGATENQLYTAEQARIVT
Protein: Amylase-binding protein AbpA (A8AZZ3)
Organism: Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288)
Interaction partners:
Sequence:
MKKVLLSSVVALTLFAAAAPVFSADEATDAARNNDGAYYLQTQFTNADKVNEYLAQHDGEIRAEAAADPAVVAAKAALDAVEGGSHNYGEVKAAYEAAFNNAFNAVRNKYVQQFQATYNNATEQEGKTYIQGETPEQANARYLKRVGAANNQNPAAEDKGATTPASKEEAKKSEAAAKNAGKAAGKALPKTSAVK
Protein: Sec sixty-one protein homolog (Ssh1 complex subunit SSH1) (Ssh1 complex subunit alpha) (P38353)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Part of the Ssh1 complex, which probably is the major component of a channel-forming translocon complex that may function exclusively in the cotranslational pathway of protein endoplasmic reticulum (ER) import.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Interaction partners:
- Protein transport protein SBH1
- Protein transport protein SBH2
- Protein transport protein SEC61
- Protein transport protein SSS1
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL24A
- Large ribosomal subunit protein uL29A
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS19
Sequence:
MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYLFAQFPLVGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKVIKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFGDDLSVVQIGLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGVSQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIISAFNRDYLPNLTTTIIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVLFSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLLAPPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEFKDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKAAGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM
Protein: Albumin (D6RHD5)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MSQLKIVTNHLYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
Protein: Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) (Q96MT7)
Organism: Homo sapiens (Human)
Function: Flagellar protein involved in sperm flagellum axoneme organization and function.
Subcellular location: Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A8J1V4}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q57WH1}.
Interaction partners:
- Glutamine-rich protein 2
- Cilia- and flagella-associated protein 69
- Dynein axonemal heavy chain 1
- Cilia- and flagella-associated protein 70
Sequence:
MKEPDDQDTDGEKSVTSKSDGKKSLRSSKSESRSPVQEDNTFLEDDTDETFTKGEGSYLEEDSDEERLEGSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMPFVTLDSNIPLDLLTLVHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVERDYKPIGYINTPGPVCQLMWSPMSHPESTLLIICENGYILEAPLPTIKQEEDDHDVVSYEIKDMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPEIFIPSTPSPILCGFYSEPGKFWVSLGGYDSGFLYHCEFPPCDESSDFKEQKDEPIDVRYLADTEDNPIQTITFNINKVMMFCGMKNGAIRVYVLNQNDPSLTSLVDYWHFNMHDNNYGCIKSIANSFDDRFLVTAGADGNIFVFNIFSEFMLRKDMKAKVPSPRFGIETEPIPEDIEDPKAYSIENARRKREHDKLMKEVGEIKARKREQIKALRSEFCNLLEMNEKLPKHMQFKRTDFDVDSQIRAEMHRKTAFKIQQVEKELAWEKEKHELGLMKLKNRFRDPLESDTIVVHAILSDHKISSYRLVQPSKYSKFKRASQSERKPSKLDRFEKEGPGRKDSQRDAGGSVTIQEESIIEKGKKFRPKTLSEIIVENQIEKTRKLILKAERAQLKIQQRKKEWEELYKSKPGDDYEDPKDLQAIKEAQVYMGDFNLKTAPDYKIPEHMRINAAKKEEELGHLDSLVHGNKRHMNKCILSLRDLKVAVVEEIQCLVQELKNIQSTLHISKHIPIPKIPQIHPEEVPEKRFQYDEETLLNFKQQQMKSKDEKSPGVEQTGSGGPVGGFLKLSSRKDGDLTTRDSISRSSKASTFSLDIPKCLEFEKAEPTDVELEIMKRDEIKHVYMQQYLVNRIKELVVTFDAELRLLRHQKLKLDTQMKLSDLHHVTLFQEILLLKNFEKQENILQERVNSLDKEEQYMQWKINETLKEMEEKKNEITKLQEQEKALYAGFQAAIGENNKFANFLMKVLKKKIKRVKKKEVEGDADEDEESEESSEEESSLESDEDESESEDEVFDDSICPTNCDVALFELALHLREKRLDIEEALVEEKKIVDNLKKEYDTLSKKVKIVATNLNAAEEALEAYQREKQQRLNELLVVIPLKLHQIEYVVFGEIPSDLSGTLVFSNHALRRLQERIHELQEENSKQQKLNKEWRERRKQLIREKREMTKTIHKMEETVRQLMISKFGRVVNLEALQTLSVNTTLEELKIRKLRKELANAKEMKMWEEKIAQMRWELMMKTKEHTRKLYQMNDLCIEKKKLDSRLNTLQNQQGNAFQGPREADVVAREEVTELIQLQAERISALKEEIALLRRKGSLILPPIQSPREKEIQPADL
Protein: Myosin light chain 2 (Calmodulin-like myosin light chain MLC2) (MYO1 light chain 2) (Myosin-1 light chain) (Q06580)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Regulatory light chain for the class II conventional myosin MYO1. May play a role in the disassembly of the MYO1 ring at the bud neck at the end of its contraction during cytokinesis.
Subcellular location: Bud neck {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:15210731}. Note=Forms a ring at the bud neck in a MYO1-dependent manner.
Interaction partners:
- Myosin-1
- Myosin light chain 1
- Ras GTPase-activating-like protein IQG1
- Myosin-2
- Tubulin beta chain
- Calcium-channel protein CCH1
- Actin
- Cytokinesis protein 2
- FK506-binding protein 1
- Cell division control protein 42
Sequence:
MDHSESLTFNQLTQDYINKLKDAFQMLDEDEDGLISRGDLTKIYATLGKTLTDEEWSKMVPDNDTSTAEVGEEGVSFPIFLSIMGKNLSQFPEREELEESLKAIGRGHDLNVPLNEVIDSLKEAGFENPEEEFAKLFKLFTTNQQATEERTFRGKLFLDSITD
Protein: Urease (EC 3.5.1.5) (Urea amidohydrolase) (Q9SR52)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Urea hydrolase involved in nitrogen recycling from ureide, purine, and arginine catabolism.
Interaction partners:
- Urease accessory protein G
- Arginase 1, mitochondrial
- Arginase 2, chloroplastic/mitochondrial
- Urease accessory protein D
- Ureidoglycolate hydrolase
- Urease accessory protein F
- Argininosuccinate lyase, chloroplastic
- Urea-proton symporter DUR3
- Mitochondrial arginine transporter BAC1
- Mitochondrial arginine transporter BAC2
Sequence:
MKLLPREIEKLELHQAGFLAQKRLARGIRLNYTEAVALIATQILEFIRDGDKSVAELMDIGRQLLGRRQVLPAVLHLLYTVQVEGTFRDGTKLVTVHEPISLENGNLELALHGSFLPVPSLDKFPEVHEGVIIPGDMKYGDGSIIINHGRKAVVLKVVNTGDRPVQVGSHYHFIEVNPLLVFDRRKALGMRLNIPAGTAVRFEPGERKSVVLVNIGGNKVIRGGNGIVDGLVDDVNWTVLMETMERRGFKHLEDIDASEGIAGEDPRFTTMISREKYANMYGPTTGDKLRLGDTNLYARIEKDYTVYGDECVFGGGKVLREGMGQGIEQAEALSLDTVITNSVIIDYSGIYKADIGIKNGHIVGIGKAGNPDTMHGVQNNMLIGNKTEVIAGEGMIVTAGAIDCHVHFICPQLVYEAVSSGITTMVGGGTGPAYGTRATTCTPSPFDMKLMLQSTDSLPLNFGFTGKGNTAKPLELRHIVEAGAMGLKLHEDWGTTPAAIDNCLAVAEEYDIQVNIHTDTLNESGFVEHTINAFRGRTIHTYHSEGAGGGHAPDIIRVCGVKNVLPSSTNPTRPYTKNTVDEHLDMLMVCHHLDKNIPEDVAFAESRIRAETIAAEDILHDMGAISIISSDSQAMGRIGEVISRTWQTADKMKAQRGAIDPNMADDDNSRIKRYIAKYTINPAIANGFADLIGSVEVKKLADLVIWQPAFFGAKPEMIIKGGNIAWANMGDANASIPTPEPVISRPMFGAFGKAGSENSVAFVSKAALRKGVKELYGLKKRVVAVSNVRQLTKLDMKLNDALPEITVDPETYVVTANGEVLTCAPADSVPLSRNYFLF
Protein: Alpha-humulene/(-)-(E)-beta-caryophyllene synthase (EC 4.2.3.-) (Terpenoid synthase 21) (AtTPS21) (Q84UU4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in sesquiterpene (C15) biosynthesis. The major products are beta-caryophyllene and alpha-humulene. Does not convert geranyl diphosphate (GPP) to any monoterpenes.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Alpha-barbatene synthase
- (Z)-gamma-bisabolene synthase 1 (Terpenoid synthase 12) (AtTPS12)
- (Z)-gamma-bisabolene synthase 2 (Terpenoid synthase 13) (AtTPS13)
- Squalene synthase 1
- Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic
- Inactive squalene synthase 2
- Dehydrodolichyl diphosphate synthase 6
- Farnesyl pyrophosphate synthase 2
- Farnesyl pyrophosphate synthase 1, mitochondrial
- Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 2
Sequence:
MGSEVNRPLADFPANIWEDPLTSFSKSDLGTETFKEKHSTLKEAVKEAFMSSKANPIENIKFIDALCRLGVSYHFEKDIVEQLDKSFDCLDFPQMVRQEGCDLYTVGIIFQVFRQFGFKLSADVFEKFKDENGKFKGHLVTDAYGMLSLYEAAQWGTHGEDIIDEALAFSRSHLEEISSRSSPHLAIRIKNALKHPYHKGISRIETRQYISYYEEEESCDPTLLEFAKIDFNLLQILHREELACVTRWHHEMEFKSKVTYTRHRITEAYLWSLGTYFEPQYSQARVITTMALILFTALDDMYDAYGTMEELELFTDAMDEWLPVVPDEIPIPDSMKFIYNVTVEFYDKLDEELEKEGRSGCGFHLKKSLQKTANGYMQEAKWLKKDYIATFDEYKENAILSSGYYALIAMTFVRMTDVAKLDAFEWLSSHPKIRVASEIISRFTDDISSYEFEHKREHVATGIDCYMQQFGVSKERAVEVMGNIVSDAWKDLNQELMRPHVFPFPLLMRVLNLSRVIDVFYRYQDAYTNPKLLKEHIVSLLIETIPI
Protein: Protein YdhQ (P77552)
Organism: Escherichia coli (strain K12)
Interaction partners:
Sequence:
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINLNGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
Protein: RuvB-like 2 (EC 3.6.4.12) (Reptin) (zReptin) (P83571)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Has double-stranded DNA-stimulated ATPase activity. Has ATP-dependent DNA helicase (5' to 3') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). Represses gene activation mediated by beta-catenin. Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding (By similarity). Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway where it negatively regulates expression of ER stress response genes (By similarity). May act as a regulator of embryonic heart growth.
Subcellular location: Nucleus {ECO:0000250}. Dynein axonemal particle {ECO:0000250|UniProtKB:Q9DE27}.
Interaction partners:
- RuvB-like 1
- PIH1 domain-containing protein 1
- Actin-related protein 5
- RNA polymerase II-associated protein 3
- Actin-related protein 6
- PIH1 domain-containing protein 2
- DNA methyltransferase 1-associated protein 1.
- INO80 complex subunit C
- Actin-like 6A
- Nucleolar protein 58
Sequence:
MAAQVATTKVPEVRDITRIERIGAHSHIRGLGLDDALEPRQVSQGMVGQLASRRAAGLILEMIKDGQIAGRAVLIAGQPGTGKTAIAMGIAQSLGPDTPFTALAGSEIFSLEMSKTEALSQAFRKAIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGTKMIESLSKERVQAGDVITIDKATGKISKLGRSFTRARDYDAMGAQTQFVQCPEGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVSEWREEGKAEIIPGVLFIDEVHMLDIECFSFLNRALESDLSPVLIMATNRGITRIRGTNYQSPHGIPIDMLDRLLIIATTPYTEKETRQILKIRCEEEDVELSEEAHTVLTRIGQETSLRYAIQLISTAGLVCRKRRGTEVQVEDIKRVYSLFLDEARSSQYMKEYQDSFLFNETQTSQMDTS
Protein: Toxin Tst1 (PT-Mice-beta* NaTx6.3) (Tst-gamma) (P56612)
Organism: Tityus stigmurus (Brazilian scorpion)
Function: Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on mammals (By similarity). Is toxic to mice.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MKGMILFISCLLLIDIVVGGKEGYLMDHEGCKLSCFIRPSGYCGRECTLKKGSSGYCAWPACYCYGLPNWVKVWDRATNKCGKK