wanglab/gogpt-training-data huggingface dataset:
Protein: Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I) (P60334)
Organism: Mus musculus (Mouse)
Function: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.
Interaction partners:
- Cysteine sulfinic acid decarboxylase
- Cystathionine gamma-lyase
- Acidic amino acid decarboxylase GADL1
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase, mitochondrial
- Brother of CDO
- Glutamate decarboxylase 2
- Glutamate decarboxylase 1
- Kynurenine--oxoglutarate transaminase 3
- Putative aspartate aminotransferase, cytoplasmic 2
Sequence:
MERTELLKPRTLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTPFTTSGSLENN
Protein: GDT1 family protein (Q8JJ62)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}.
Interaction partners:
- Sodium/bile acid cotransporter 7
- Transmembrane 9 superfamily member
Sequence:
MPLRAGERHGGGRFICFLVLLSVVLFSAGVTATQEEKKVINEEQPAEVQKGTTDHAPGPAIRVDEPNKGNLGFIHAFAAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTIIPRIYTYYISTALFAIFGVRMLREGLRMSPDEGQEELEEVQAEIKKKDEELQRYKLANGAPDVEAGTAANMLPQRKWPSLISPIFIQALTLTFLAEWGDRSQLATIVLAAREDPFGVAVGGTLGHCLCTGLAVIGGRMVAQKISVRTVTIIGGIVFLAFAFSALFIKPDSGF
Protein: GTP pyrophosphokinase (EC 2.7.6.5) ((p)ppGpp synthase) (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthase I) (P52560)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Function: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp. PppGpp could play an essential role in triggering antibiotic production under some nutritional conditions.
Interaction partners:
- Hydrolase
- Guanylate kinase
- Uncharacterized protein SCO0757
- Small ribosomal subunit protein bS6
- Pyruvate kinase
- Small ribosomal subunit protein uS12
- Pyruvate kinase
- Large ribosomal subunit protein uL13
- Uncharacterized protein SCO3348
- Large ribosomal subunit protein uL11
Sequence:
MPDEAQPLTAAKPESASASAAKPAPSAPQAKNDTHGPIQHAPAAPVDKPAEQQPRPKPLPAERPQNAPVVRAPAGQPARSGSSNRVRARLARLGVQRANPYNPVLEPLLRIVRGNDPKIETSTLRQIERAYQVAERWHRGQKRKSGDPYITHPLAVTTILAELGMDPATLMAGLLHDTVEDTEYGLEDLRRDFGDVVTLLVDGVTKLDKVKFGEAAQAETVRKMVVAMAKDPRVLVIKLADRLHNMRTMRYLKREKQEKKARETLEIYAPLAHRLGMNTIKWELEDLAFAILYPKMYDEIVRLVAERAPKRDEYLAVVTDEVQQDLRAARIKATVTGRPKHYYSVYQKMIVRGRDFAEIYDLVGIRVLVDTVRDCYAALGTVHARWNPVPGRFKDYIAMPKFNMYQSLHTTVIGPGGKPVELQIRTFDMHRRAEYGIAAHWKYKQEAVAGASKVRTDAPKSSGKSKDDHLNDMAWLRQLLDWQKETEDPGEFLESLRFDLSRNEVFVFTPKGDVIALPAGATPVDFAYAVHTEVGHRTIGARVNGRLVPLESTLDNGDLVEVFTSKAAGAGPSRDWLGFVKSPRARNKIRAWFSKERRDEAIEQGKDAIVRAMRKQNLPIQRILTGDSLVTLAHEMRYSDISALYAAIGEGHVSAPNIVQKLVQALGGEEAATEEIDESVPPSRGRGRKRRANADPGVVVKGVEDVWVKLARCCTPVPGDPIIGFVTRGSGVSVHRSDCVNVDSLSREPERILEVEWAPTQSSVFLVAIQVEALDRSRLLSDVTRVLSDQHVNILSAAVQTSRDRVATSRFTFEMGDPKHLGHVLKAVRGVEGVYDVYRVTSARRPS
Protein: LD33331p (R and B) (Q9VAH2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Exosome complex exonuclease RRP44
- Protein hobbit
- Dis3 like 3'-5' exoribonuclease 2, isoform C
- Exosome complex component RRP45
Sequence:
MFWTPEQVESMLEVLKTSTDRTVIYKCLVKLRTDLVKDKNGIVLFRTAGGVHIMVRLITKLNEKIMEVVLSILGNCCTDEQSCIEAVECKVIHPLVTILKTIPNPLIQCRACRMLGNIAKSKKASQCLTVHYAAIAPAICHIIESTSAVQTRIMAFRVCRFLLASSQFLKYFLMANGFQQLMRIFLAVMKNEEASKEPVPDIEMSTLIGLKRNQHREKYFEEVARNLEGVRSDIFDHQMLKNSTRNCDYALPKENEAAVELALEILKCLVLISAQQIGLKVWESISWNTSLASIVCFVKEDGDQRASALKILSNFCKDPFAFYMLSTADAIVAACEMLMAVNMAKPLSESESRHCINIILTLSTDACSRSKIRRCGALRKLVAMIRDSNSQSERSSLFHILYNFQYDNLSMELMLYEGLMPMLVRELNDYLTSDDEHHKRRRDERLQGGKKRKLTDPTTPETLSKFSKTHETLGSDFESPSSSPRSYRTTSPCSSRSMSPVCTDLLTNDDDDNYSPACSDDDEDEDDSTNNSNLDTRERRIAANRSQPSNVLDILKLIEEGSEPIDDPLSDKEDLEELSSDVPPKLAPFRNTTCNTIDIIENLIYRITLMVNKRVELGKPETLDTLIRAIKLFGSNNNFPNALTNILLESQFFAQIIKHGVVHQLYQFTKLKEIRKDGFAFLETLTNVGESNYGKEELVRLLRCDDVISQQRAAISVAYIVKSHRLLYQFLYDGNALNMLFDMMLRKKTEDHYADEAADAVTSMARYTLGIVMPEAEPAESTAGICNQIANDTAPLHANCDMRFLVGHGADSTSIGFNKQLLCDTSEVFNKMLNSDFREGHQGEIQLPDYTASGLRYFLHLIVCQERHLTEPDYPALLQAYEMARVYIMPDMEAVLQQRLIQYLDSHNCLRLLEWALKNYHADLTETAISFYLCSALPAQEKLQLFRAAEDSTYASEWFQLLNDAVFERCRGYVF
Protein: Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (D4A8N1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Endoplasmic reticulum {ECO:0000256|RuleBase:RU365083}.
Interaction partners:
- Dolichol-phosphate mannosyltransferase subunit 3
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Dol-P-Man:Man
- dolichol kinase
- Chitobiosyldiphosphodolichol beta-mannosyltransferase
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- Mannose-1-phosphate guanylyltransferase catalytic subunit beta
- ALG5, dolichyl-phosphate beta-glucosyltransferase.
- Mannose-1-phosphate guanylyltransferase regulatory subunit alpha
- Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
Sequence:
MASTGASRSLAASQRPPQGRSSRQDKYSVLLPTYNERENLPLIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLEKIYGPDRILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVRARQMDYTVGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT
Protein: Large ribosomal subunit protein uL16m (60S ribosomal protein L16, mitochondrial) (P46801)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Mitochondrion.
Interaction partners:
- Large ribosomal subunit protein uL14c
- Small ribosomal subunit protein uS14c
- Large ribosomal subunit protein bL27c
- Os01g0220300 protein
- Large ribosomal subunit protein mL46
- Large ribosomal subunit protein uL2m
- Small ribosomal subunit protein uS2c
- Large ribosomal subunit protein bL33c
- Os06g0683200 protein
- Large ribosomal subunit protein bL36c
Sequence:
MEKHLVMYLTRKSIMLLRKYPLVTEFQVSKCGSHIVKIRRDVLYPKRTKYSKYSKCRCSRGCEPDGTQLGFGRYGTKSCRAGRLSYRAIEAARRATIGQFHRAMSGQFRRNCKIWVRVLADLPITGKPAEVRMGRGKGNPTGWIARVSTGQIPFEMDGVSLSNARQAARLAAHKPCSSTKFVQWS
Protein: RNA-binding region RNP-1 domain-containing protein (Q75K16)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Nucleolar protein 56
- rRNA 2'-O-methyltransferase fibrillarin
- Nucleolar protein 58
- Putative pre-rRNA-processing protein esf2
Sequence:
MAKDQKAIESKKRKKEESESETESSEENNASSSSESESEDELKVVGEGSSSSKSTFTKKESAAKDESSNTKTDDDLKVFVGQLPSGVTEYDLKEYFSECGDISNIKILNSNPQRVAAFITFADEKGRDTAITYNGKDFNGQGSLRINGANSKPSDGEGEPTTIVCRNIAFTVDETLVKEFFSKCGSISRVSLPVYEDSGRLKGFAFVSFDSEDAVEKAIALTGTKFEGREIQVERSQRGGGRSSSFGRGGGRGGFGGGRGGRGGFGNGGGRGGFGGGRGGGRGGSGGRGGFGNKRGRFE
Protein: Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (Q55FE0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Interaction partners:
- Eukaryotic translation initiation factor 4 gamma
- Eukaryotic translation initiation factor 4E-1A-binding protein homolog
- Eukaryotic initiation factor 4A
- von Willebrand factor A domain-containing protein DDB_G0286969
- Nuclear cap-binding protein subunit 1
- Protein pirA
- Uncharacterized protein
- Uncharacterized protein
- RNA helicase
- Polyadenylate-binding protein 1-A
Sequence:
MTTNKDVECLVEPTSNISITEENKNVTSETTTTTNNTQNKETETTDNINKEETADKENKEEQQQEENPENLIKHPLQNRWSLWYDYQSGKINPEHWVDSLKKVISFDSVEDFWCVFNNLPNVSNLKQGSSYHLFKDDIEPKWEHESNKRGGKWFVMVKDKSRCDNQWLQSVMACVGETFDSSDEICGIVYNSRKNGDKISVWTKTAQDEKATRDVGNCLKKILEIDQTIQYTPHEDFIRSSKGSKNLYEC
Protein: Leiomodin-2 (Cardiac leiomodin) (C-LMOD) (E1BTG2)
Organism: Gallus gallus (Chicken)
Function: Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity). Plays a role in the regulation of actin filament length. Required for normal sarcomere organization in the heart, and for normal heart function (By similarity).
Subcellular location: Cytoplasm, myofibril, sarcomere {ECO:0000269|PubMed:20736303}. Cytoplasm, myofibril {ECO:0000269|PubMed:20736303}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000269|PubMed:20736303}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20736303}. Note=Colocalizes with actin filament pointed ends in sarcomeres. Detected close to the M line. {ECO:0000269|PubMed:20736303}.
Interaction partners:
- Myozenin 2
- Myosin binding protein C, slow type.
- Cysteine and glycine rich protein 3
- Musculoskeletal embryonic nuclear protein 1
- Ankyrin repeat and SOCS box containing 15.
- Uncharacterized protein.
Sequence:
MSTFGYRRELSKYEDIDEDELLASLTEEELKELERELEDIEPDRNLPVGQRQKSLTEKTPTGTFSREALMAYWERETRKLLEKERLGACEKDSEQEEDNSEDIQEECFTESNSEVSEEAYTEEDDEEEEEEEEEEEDEDDSDDEDEEKQNSAASERPVNCEDGRSSSHVRHKKCSNAKNSENLFNGHDGKDTENLSFKSSAIHPCGNPTVIEDALEKVRSNDPETTEVNLNNIENITSQMLIQFSQALRDNTVVKSFSLANTHADDNVAIAIAGMLKVNQHITSLNIESNFITGKGVLAIMRALQHNKVLTELRFHNQRHIMGSQVEMDIVKLLKENTTLVKLGYHFDLAGPRMSMTSILTRNMDKQRQKRMQEQRQQEYGCDGAINPKTKVLQKGTPRSSPYTSPKSSPWSSPKLPRKSAPAKSQPPAPAPPPPPPPPPPPPPPPPPVIPDKKAPTRNIAEVIKQQESSRKALQNGQKKKKGKKGKKHENSILKEIKDSLKSVSDRKSEEGSRPSTRPSTPQRSLHDNLMEAIRASSIKQLRRVEVPEALR
Protein: Arylsulfatase D (ASD) (EC 3.1.6.-) (P51689)
Organism: Homo sapiens (Human)
Subcellular location: Lysosome {ECO:0000305}.
Interaction partners:
- Glycoprotein Xg
- Mediator of RNA polymerase II transcription subunit 14
- Formylglycine-generating enzyme
Sequence:
MRSAARRGRAAPAARDSLPVLLFLCLLLKTCEPKTANAFKPNILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFLTGRHSFRSGMDASNGYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKWHQGVNCASRGDHCHHPLNHGFDYFYGMPFTLTNDCDPGRPPEVDAALRAQLWGYTQFLALGILTLAAGQTCGFFSVSARAVTGMAGVGCLFFISWYSSFGFVRRWNCILMRNHDVTEQPMVLEKTASLMLKEAVSYIERHKHGPFLLFLSLLHVHIPLVTTSAFLGKSQHGLYGDNVEEMDWLIGKVLNAIEDNGLKNSTFTYFTSDHGGHLEARDGHSQLGGWNGIYKGGKGMGGWEGGIRVPGIFHWPGVLPAGRVIGEPTSLMDVFPTVVQLVGGEVPQDRVIDGHSLVPLLQGAEARSAHEFLFHYCGQHLHAARWHQKDSGSVWKVHYTTPQFHPEGAGACYGRGVCPCSGEGVTHHRPPLLFDLSRDPSEARPLTPDSEPLYHAVIARVGAAVSEHRQTLSPVPQQFSMSNILWKPWLQPCCGHFPFCSCHEDGDGTP
Protein: Focal adhesion kinase homolog FAK56 (Q9U472)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNTAGATSQPPPTKNEINSEEYLIHVHMPNKSFKAVRFNVKETVFHVIRRTVEDLGTDGRTPSIQRYACRMLNMITKEVIWLARSTSMQKVLSHILTPGCSNVDCPNNQSELDEVLLEHGRRITDNRVWRVELRVRYVPNNIQELFEEDKATCFYYFNQVKEDFIQANVTAIDTEVAVQLCCLGIRHYFKNITVKAPDKKQHIDYIEKEIGFKSFLPQSVIATSKPKNLKKLIQVGYKKVYNYNDIEYLTRFFDLLKNIYLTNFEQFSVTLSSAWNISGILHVGPHIGISYQTHPQASLKNVAQFKDVVSIKTCTLPKEKLSKSGENTTEPELQNFNCNCQKIKTQIKISASNNVEDLVITCNGINTAESIADLIDGYCRLLSKDLEFTIWHRETNASNEDSAKALPNDATLGSNKSTSSQGKPMLTDDYAEIGLLEGEGDYSTPTVRNYELDRSLITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEILIEDSINSSETLKREQRKVASMSWIGSDDIDIPPSKPSRVMHDPDITGLMPETTGLPQTYIIAQNPAVLAKLMMENQKRGINPAAYTTPASGIHNVLGEKLRQQQKDSNSDSEWLIQEELLRQRSCSIPQGSLNDHQAQMFKLDFMSAGPSSLPDCSNSSSRPMTPNANLSSLKSNHSSADHLSSLTSAEEQMGSNARNLGSAVPSRPPNRADDEVYCATTLVVKSIMALSQGVEKANTEGYLELVKNVGVKLRNLLTSVDKISIIFPAQALKEVQMAHQVLSKDMHELVSAMRLAQQYSDTTLDCEYRKSMLSAAHVLAMDAKNLFDVVDSIRQRYQHLFPPSATKETSCSSSFESTSGSIVTEPVNDLGGYIKTSTSGDLLQNTGIYDNDLHHSFNSQLQLQNPKASIDLSGGGSLQRGMSLGLDTTRSTNEPLRIVEETLGSPGEHMYCNTSALHGHA
Protein: Protein wings apart-like (Protein parallel sister chromatids) (Q9W517)
Organism: Drosophila melanogaster (Fruit fly)
Function: Has a role in female meiotic chromosome segregation in females; proximal heterochromatin is involved in chromosome pairing during female meiosis. Is a dominant suppressor of both white and Stubble position-effect variegation (PEV), while it is a weak enhancer of brown variegation.
Interaction partners:
- Precocious dissociation of sisters 5, isoform A
- Structural maintenance of chromosomes protein
- FI11703p
- MAU2 chromatid cohesion factor homolog
- Nipped-B protein
- LD34181p
- separase
- Structural maintenance of chromosomes protein
- Chromosomal protein D1
- CTCF
Sequence:
MSRWGKNIVVPLDSLCKEKENTNRPTVARSVGTVGKWGKMGFTSTRTYTLPAIHPMAAAAAAAAAAASPSQSPASTQDHDPNDLSVSVPEPPKPKKFFKSRNTAPPEVIAQIIQQLPHCGAGASPMRDHFSSAGAGAGGLTPTSGAQEAGGVKLKPGKGASSAERKRKSPKKKAATTSASTPSTPGAFYGASDRDGDGLSDPASEQPEQPSSASGKQKQKKPKEEKKLKPEAPPSRVLGRARKAVNYREVDEDERYPTPTKDLIIPKAGRQPAEVAATATLAAASSEAFISSTFGSPGSEPSLPPPTSAPSASASTSSQLPSASGSASNPPSASRTPEHPPIVLRISKGTSRLVSTDSEEPPSSSPAHQNQLNQLSVTEEEPAERSGDETVPASTPKITVKPLRPPTAADSVDGSSAAVGGASAGDSFEERKSQSLEPNEDEEEEEEEEDEEEEPPEINYCTVKISPDKPPKERLKLIIKTDVIRNAIAKAAAAAESRSEKKSRSKKHKHKQLLAAGSGAAPASGATPAEINSEFKTPSPHLALSEANSQQAQHTPSHLHQLHQLHPQRGSAVISPTTRSDHDFDSQSSVLGSISSKGNSTPQLLAQAVQEDSCVIRSRGSSVITSDLETSQHSSLVAPPSDIESRLESMMMTIDGAGTGAASAVPETPLQEDILAVLRGEVPRLNGNTDPEPTEEEDQQQQPKRATRGRGRKANNNVDVTPPATETRTRGRAKGADATTAAISPPTGKRNTRGTRGSRKAEQEVDMEVDETAMTTVPANEEQLEQATLPPRRGRNAAARANNNNLASVNNNINKIAANLSAKAEASRLAEGGVAGGAARSYGRKRKNQQVTQVLQQEPVPEEQETPDAEEEQPTPAKIPHTDHREHSPDHDPDPDPDELSNNSNNSSLQHDGSSSSPPPRDFKFKDKFKRTLTLDTQGAANAGAGGAAAAAPPESSGEQRGAVKLVISKKKGSIFKSRALVPSDQAEQATVAKRHLYKHSWDAALEANGGGTNSDASNASASGVGVAGAKDHLHHLAAGKSDGDFGDSPSSNNNGSSSACSSASTLRGDSPALGKISRLAGKQGVPATSTSSDAFDLDLEPIAGELDLERSAAGASAGGTGATTGGGGATGGGGPVRVDRKTKDYYPVVRNVKTAHQIQEIGEYQEMDDDVEYILDALQPHNPPATRCLSALQLAAKCMMPAFRMHVRAHGVVTKFFKALSDANKDLSLGLCTSAIMYILSQEGLNMDLDRDSLELMINLLEADGVGGSTETGHPDRAGYDRNKQKVRELCEEIKAQGKGTHLNVDSLTVGTLAMETLLSLTSKRAGEWFKEDLRKLGGLEHIIKTISDFCRPVIACDTEIDWQPTLLDNMQTVARCLRVLENVTQHNETNQRYMLTSGQGKAVETLCQLYRLCSRQIMLHPSDGGGSNKEHPGVAMRELLVPVLKVLINLTHTFNEAQPSLGAELLGQRGDVVETSFRLLLLSANYIPDQCVFELSILVLTLLINLCMHTVPNRAALMQAAAPAEYVADNPPAQGSVSALQALLEYFYKCEELARLVEKNTDAFLESNEKGKKKQEEVEETVNNLVQRAGHHMEHTLKGSYAAILVGNLIADNELYESVVRRQLRGNSFKEIIGVLEKYHTFMNLTSSLEAAFVAHMKSTKRIIDNFKKRDYIYEHSDEHDNPLPLNLETTAQVLAVGADASHAATSSTTVGSGSAPSSTSATGTTRAPRVYKTYSSHR
Protein: Envelopment polyprotein (M polyprotein) [Cleaved into: Glycoprotein N (Gn) (Glycoprotein G2); Non-structural protein M (NSm); Glycoprotein C (Gc) (Glycoprotein G1)] (P04505)
Organism: Bunyamwera virus (BUNV)
Function: Glycoprotein N and Glycoprotein C interact with each other and are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity).
Subcellular location: [Glycoprotein C]: Virion membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Host Golgi apparatus membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Host endoplasmic reticulum membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Glycoprotein C alone is retained in the membrane of the endoplasmic reticulum, but not transported to the Golgi. Coexpression of Glycoprotein N and Glycoprotein C results in efficient transport of Glycoprotein C to the Golgi complex, indicating that their interaction is essential for proper targeting to this organelle, where virion budding occurs.; SUBCELLULAR LOCATION: [Glycoprotein N]: Virion membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Host Golgi apparatus membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Glycoprotein N is retained in the Golgi complex through a Golgi retention signal, which resides in the Glycoprotein N transmembrane region.; SUBCELLULAR LOCATION: [Non-structural protein M]: Host Golgi apparatus membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MRILILLLAVTQLAVSSPVITRCFHGGQLIAERKSQTSISEFCIKDDVSMLKSEIVYTKNDTGIFGHSKVFRHWTITDWKACNPVVTAGGSINVIEVDKNLNLVTRNYVCTGDCTITVDRKNAQIIFQTDKLNHFEVTGTTISTGWFKSKASVTLDRTCEHIKVSCGKKTLQFHACFKQHMSCVRFLHRSILPGSMAISICQNIELIIITILALCIFIIMIILTKTYICYVLIPVFMPIAFAYGWAYNRSCKKCTCCGLAYHPFTNCGSYCVCGSKFETSDRMRMHRESGLCQGFKSLRVARRLCKSKGSSLIISILLSVLILSFVTPIEGTLTNYPTDQKYTLDEIADVLQAKTHEDSTKYYIILYTSLFGAGLTIIFAGVALGLTIILEVLTKINVIFCNECNMYHSKKSIKYVGDFTNKCGFCTCGLLEDPEGVVVHKAKKSCTYSYQINWVRGIMIFVAFLFVIQNTIIMVAAEEDCWKNEELKEDCVGPLIAPKDCTDKDHKTYLSEASLLATAKKITQVDAENVEILGKTMESAIRVIERQKTYHRMHLLEAVFLNKHCDYYKMFEHNSGYSQVKWRMMIKTQHFDICALQANSPFCAQCIADNSCAQGSWEFDTHMNSTYSSKVDNFKHDFSLFLRIFEAAFPGTAYVHLLTNIKEKKPYQAVSMIEKIKKKFPNNKLLIGYLDFGKYLLGLSHASTYELQQRQLDKLYQPTELTRSGGQQTSLANSVVGQATKECKKYKDVSCLSPRFGIPLEDLISCCDQPNYNIYKKPKKVYKAHDKEETWCINDQHCLVDFVPAEADTVEKLKPMKCWLVDPGKNDDVYSIAIKTCRVVDKGVCTVNSQKWNIIKCDSGPLYYSDHIPGEDTGNDIGHYCVSAGCKTDRYPINPDVVTDCVWEFTSRKSQYIGKISMQSLEDYEKALTDRLTHTLETYSFAPLENLPHIKPVYKYITAQGVENSDGIEGAFITASIPAAGGTSIGYNVRSKDGFPLLDLIVFVKSAVIKSTYNHIYDTGPTISINTKHDEHCTGQCPSNIEHEANWLTFSQERTSRWGCEEFGCLAVNTGCVFGSCQDVIRPETKVYRKAVDEVVILTVCITYPGHTFCTEINAIEPKITEEIELQFKTVDTKTLPYIVAVNNHKLYSGQINDLGTFGQMCGNVQKTNSSILGTGTPKFDYTCHGASRKDIIVRRCYNNNFDSCKLLKEETQLIFNDDHDTITVYNTNHLIGELAIKLILGDIQYKLFTETLDLQIDAKCVGCPDCFESYSCNFQIVSNIDTICSLEGPCDTFHNRISIKAMQQNYAVKLSCQKDPRPSGTFKICNREYTVVFHTVAKDDKIEINVGDQTSFIKEKDDRCKTWLCRVRDEGISVIFEPIKAFFGSYFSIFFYIIVVVVVGFLIIYIFMPMFMKLKEVLKANEKLYLQEIKQK
Protein: Transcription initiation factor TFIID subunit 1b (TAFII250-B) (TBP-associated factor 1b) (AtTAF1b) (Transcription initiation factor TFIID subunit 1-B) (Q6PUA2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Core scaffold of the TFIID complex. Acts as a histone acetyltransferase involved in the light regulation of growth and gene expression. Required for H3K9, H3K27, and H4K12 acetylation on the target promoters.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 13
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 7
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 11
- Transcription initiation factor TFIID subunit 12b
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 4
Sequence:
MICRVDYGSNDEEYDGPELQVVTEEDHLLPKREYLSAAFALSGLNSRASVFDDEDYDEQGGQEKEHVPVEKSFDSEEREPVVLKEEKPVKHEKEASILGNKNQMDTGDVQEELVVGLSEATLDEKRVTPLPTLYLEDDGMVILQFSEIFAIQEPQKKRQKREIRCITYRDKYISMDISELIEDDEEVLLKSHGRIDTHGKKTDQIQLDVPLPIRERSQLVKSGIVRDTTSESREFTKLGRDSCIMGELLKQDLKDDNSSLCQSQLTMEVFPLDQQEWEHLILWEISPQFSANCCEGFKSGLESAGIMVQVRASNSVTEQESLNVMNSGGQTQGDNNNMLEPFFVNPLESFGSRGSQSTNESTNKSRHHPQLLRLESQWDEDHYRENGDAGRENLKQLNSDARGRLSGLALQDRDMWDESWLDSIIWESDKDLSRSKLIFDLQDEQMIFEVPNNKERKYLQLHAGSRIVSRSSKSKDGSFQEGCGSNSGWQFNISNDKFYMNGKSAQKLQGNAKKSTVHSLRVFHSAPAIKLQTMKIKLSNKERANFHRPKALWYPHDNELAIKQQKILPTQGSMTIVVKSLGGKGSLLTVGREESVSSLKAKASRKLDFKETEAVKMFYMGKELEDEKSLAEQNVQPNSLVHLLRTKVHLWPWAQKLPGENKSLRPPGAFKKKSDLSNQDGHVFLMEYCEERPLMLSNAGMGANLCTYYQKSSPEDQHGNLLRNQSDTLGSVIILEHGNKSPFLGEVHGGCSQSSVETNMYKAPVFPHRLQSTDYLLVRSAKGKLSLRRINKIVAVGQQEPRMEIMSPASKNLHAYLVNRMMAYVYREFKHRDRIAADELSFSFSNISDATVRKYMQVCSDLERDANGKACWSKKRKFDKIPLGLNTLVAPEDVCSYESMLAGLFRLKHLGITRFTLPASISTALAQLPDERIAAASHIARELQITPWNLSSSFVTCATQGRENIERLEITGVGDPSGRGLGFSYVRVAPKSSAASEHKKKKAAACRGVPTVTGTDADPRRLSMEAAREVLLKFNVPDEIIAKQTQRHRTAMIRKISSEQAASGGKVGPTTVGMFSRSQRMSFLQLQQQAREMCHEIWDRQRLSLSACDDDGNESENEANSDLDSFVGDLEDLLDAEDGGEGEESNKSMNEKLDGVKGLKMRRWPSQVEKDEEIEDEAAEYVELCRLLMQDENDKKKKKLKDVGEGIGSFPPPRSNFEPFIDKKYIATEPDASFLIVNESTVKHTKNVDKATSKSPKDKQVKEIGTPICQMKKILKENQKVFMGKKTARANFVCGACGQHGHMKTNKHCPKYRRNTESQPESMDMKKSTGKPSSSDLSGEVWLTPIDNKKPAPKSATKISVNEATKVGDSTSKTPGSSDVAAVSEIDSGTKLTSRKLKISSKAKPKASKVESDSPFHSLMPAYSRERGESELHNPSVSGQLLPSTETDQAASSRYTTSVPQPSLSIDKDQAESCRPHRVIWPPTGKEHSQKKLVIKRLKEITDHDSGSLEETPQFESRKTKRMAELADFQRQQRLRLSENFLDWGPKDDRKWRKEQDISTELHREGKVRRAYDDSTVSEERSEIAESRRYREVIRSEREEEKRRKAKQKKKLQRGILENYPPRRNDGISSESGQNINSLCVSDFERNRTEYAPQPKRRKKGQVGLANILESIVDTLRVKEVNVSYLFLKPVTKKEAPNYLEIVKCPMDLSTIRDKVRRMEYRDRQQFRHDVWQIKFNAHLYNDGRNLSIPPLADELLVKCDRLLDEYRDELKEAEKGIVDSSDSLR
Protein: Uncharacterized protein C11D3.04c (Q10083)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Uncharacterized transporter C530.02
Sequence:
MSQDSESFIRQLFKAFTDFSTDVESLRGFLTPDYRQLVDGRELTLDDFISHAKALRTHLHRLDINVQQIVCQGNKAATVHIAHAIRSSGESSRIKVIAFYSFKDGRISLIDELTYVLEGGNADRELGSVQ
Protein: Probable phosphatase C1687.21 (EC 3.1.3.-) (O94461)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Triosephosphate isomerase
- Phosphoglycerate kinase
Sequence:
MKVFLIRHGQTDQNKRGILQGSVDTNLNETGRLQAKLLAQRLLPLDIDQIFCSSMKRCRETIAPYLELKPEVPIVYTDLIRERVYGDLEGMNVVEAKKLLNANHPDHYGEGLSHLTSRLLKFWDEYVVPLQGKKKCVIVLCHGGVINVLRTHFMEEKGFTFDKSKLESKIITFNTSITEIEVTEHGTGHIHTFGDASHLESEETGKLIA
Protein: ATP-binding cassette protein, putative (Q389P2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ABC transporter, putative
- GST N-terminal domain-containing protein
- Elongation initiation factor 2 alpha subunit, putative
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S13, putative
- Large ribosomal subunit protein bL21m
- 40S ribosomal protein S16, putative
- 60S ribosomal protein L4
- 60S ribosomal protein L35, putative
- 40S ribosomal protein S23, putative
Sequence:
MSSLSTAGCVGDANVLGDSDVKVSVLSRKDRKKQERTEKLLEEQRQLREQANCVNKDGDNPFSVTWEHDKGTEGSRDISLQRVAVSVNGKVLFKDTQVRLSAGARYGLMGPNGRGKSTILRLLSSRELPVQSNLELLLVEQEQEFHESEVSAVQAVLQSHKKQREFASEAAQLHEKTELSHEEMERLNFLEEELDIMGAAQAEARARRILFGLGFPTEWHERPTSSFSGGWRKRIALAAAVFIEPDVLMLDEPTNHLDLNAVIWLESYLCEQYNEKARRPKTLVVVSHDAGFLDEVCTHMVHVENYQLNYYRGGFSGFDEQLRQRHQEIDKKYATFNKTINEKKRNGMSNAQVDEWIKDQVRTGRLDPIYLEKRRDYIVNFPFSEPPELPDGYIVKLEDVSFNYPGGPVLFHKVSCALWADSRITLCGPNGIGKSTLLSLLTGQLEPTEGIITMNRKVRIGRYNQHFVDKLPLEKTSVEFIQSLGIREEDKARRQLGSFGLEGIVHKNQIATLSGGQKARVALAAISAEKPHFLLFDEPTNHLDVESIEALCHAIKNFKGGVLVVTHDARLIEETDMQIWEAGNQNVRPFNGSLNDYKNKVRREFEEQEKKMLKERHIATEEKQLNSRLAREGAGKDVAALKKEKEEETRQRQLAELDAAFALLDKRKKVKKVKKDKEEKANDG
Protein: D-gluconate/D-galactonate dehydratase (GAD) (GNAD) (EC 4.2.1.140) (EC 4.2.1.39) (EC 4.2.1.6) (Q97U27)
Organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Function: Involved in the degradation of glucose and galactose via the branched variant of the Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is also able to catalyze the dehydration of galactonate to produce 2-keto-3-deoxygalactonate (KDGal).
Interaction partners:
- 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase
- 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
- Mandelate racemase/muconate lactonizing enzyme C-terminal domain-containing protein
- gluconate dehydratase
Sequence:
MRIREIEPIVLTSKEKGSATWASIMIVTRVITENGEVGYGEAVPTLRVISVYNAIKQVSKAYIGKEVEEVEKNYHEWYKQDFYLARSFESATAVSAIDIASWDIIGKELGAPIHKLLGGKTRDRVPVYANGWYQDCVTPEEFAEKAKDVVKMGYKALKFDPFGPYYDWIDERGLREAEERVKAVREAVGDNVDILIEHHGRFNANSAIMIAKRLEKYNPGFMEEPVHHEDVIGLRKYKASTHLRVALGERLISEKETAFYVEEGLVNILQPDLTNIGGVTVGRSVIKIAEANDVEVAFHNAFGSIQNAVEIQLSAVTQNLYLLENFYDWFPQWKRDLVYNETPVEGGHVKVPYKPGLGVSINEKIIEQLRAEPIPLDVIEEPVWVVKGTWKNYGV