wanglab/gogpt-training-data huggingface dataset:
Protein: Homeobox protein Hox-B1 (Homeobox protein Hox-2.9) (P17919)
Organism: Mus musculus (Mouse)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.
Subcellular location: Nucleus.
Interaction partners:
- Pre-B-cell leukemia transcription factor 1
- Homeobox protein Hox-D1
- Homeobox protein PKNOX1
- Homeobox protein Meis1
- Pre-B-cell leukemia transcription factor 4
Sequence:
MDYNRMSSFLEYPLCNRGPSAYSAPTSFPPCSAPAVDSYAGESRYGGGLPSSALQQNSGYPVQQPPSSLGVSFPSPAPSGYAPAACNPSYGPSQYYSVGQSEGDGSYFHPSSYGAQLGGLPDSYGAGGVGSGPYPPPQPPYGTEQTATFASAYDLLSEDKESPCSSEPSTLTPRTFDWMKVKRNPPKTAKVSELGLGAPGGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGRMPAGPPGCPKEAAGDASDQSACTSPEASPSSITS
Protein: Large ribosomal subunit protein eL27 (60S ribosomal protein L27) (A1XQU5)
Organism: Sus scrofa (Pig)
Function: Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P61353}. Cytoplasm {ECO:0000269|PubMed:24930395}. Rough endoplasmic reticulum {ECO:0000269|PubMed:24930395}. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (PubMed:24930395). {ECO:0000250|UniProtKB:P61353, ECO:0000269|PubMed:24930395}.
Interaction partners:
- Ribosomal protein L37
- Large ribosomal subunit protein uL18
- Uncharacterized protein.
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein eL34
- Large ribosomal subunit protein uL29
- Ribosomal protein L24.
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein uL5
Sequence:
MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF
Protein: Protein RecA (C1F5L9)
Organism: Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Interaction partners:
- LexA repressor
- DNA polymerase I
- Protein RecA
- Protein RecA
- UmuC domain-containing protein
- ATP-dependent DNA helicase RecQ
- Regulatory protein RecX
- Error-prone DNA polymerase
- DNA 3'-5' helicase II
- DNA 3'-5' helicase
Sequence:
MPSASTLRQQIESALAHRIPSALTPAPRVIRPMIPTGVAEMDAMLDGGLPVGAMTEMAGPETSGRTALALSFLRSLTDTGRACAWIDVSDTFDPESAAAVGVDLARVLWVRCGVPKAAMKPSRELQFSLPEKYLIAASTKKGVHGGGCGGHPRKEVKGLAGAVHELLRPETFAPRCAEPQRRVRTEREAFLPQPQTSPAPANTRSHSGKPWTRIEQALRATDLILQAGGFSTIVLDMGSIAPEHTSRVPLATWFRYRAAAERAQSSFLLLTQHPCAKSSSELLLKFLPGEARHDEATVFTGLAHRVEVERQRFTQPPSNVVALRKTPQRANATLWKSQTPWAGAR
Protein: Cathepsin B-like cysteine protease (Q6R7Z5)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MHLMRACITFCIASTAVVAVNAALVAEDAPVLSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKKNNNASILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRRGSSECGIEDGGSAGIPLAPNTA
Protein: Hyphally regulated cell wall protein 3 (Adhesin-like protein HYR3) (Q59XA7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence.
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:21841123}. Membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Interaction partners:
- Probable circularly permuted 1,3-beta-glucanase PGA52
- Predicted GPI-anchored protein 26
Sequence:
MHLFKRIALTLWLIISSTLAVVITEDRVDRGTISVNLGEVTVNSGASWSIINNAVTAFAGKINVQSGGGLYISSTSPLLALQVTLTSLLDSITNDGVISLDSRASLTASNYNLIGLSFTNNGEMYLAASGVLPSTMDLTAASWTNNGLIVAYQNQRSSGVLNLGTPLGAITNNGQICLYNQVYQQQTRIEGSGCITANKNSAIYISNAVLPVATTQNFYLQDSKSSMIVQAVSSTQTFNVYGFGNGNKIGITLPAVGIPPNPAYSYDVDTGILTVRAGLLSQKFNIGLGYYSLFFSVVTDNGAGLPSTILGSISYSGPVPSRNLPASCKIACKPVPTAPGTNPTEYTTTITTTNSAGNPLTETGVVDISTDSNGSWFTTTSIFPTTSQSSSSETVASSSQPDSSSTEPSAFPSSTGDSSAEPSITSDYSSSELSVVPSSASESASESSAEPSSASESASESGSESVASETSASESASEQSSTSESVSSEFASSDSSSEPSSASESSVESSSASEFVVPSSATETSVSESASESSAEPSSASESVASESAVSETSASESAAPSSASETSVSESAASSSASESFASESSVESSAVPSSASEFSTSESVASETPASETPASETPASESASEQSSTSESSAEISSASESSAEPSSAKSAISESASEFSAAPSSASQSSASQSSTNESSSQQSSAESSSTGTSSVSASAATSEYTATWTTTNSDGSVSTESGIISQSGSSFTTITTFVPDATSEYTTTWTTTNSDGSVSTESGIVSQSGSSFTTITTFAPDATSEYTTTWTTTNSDGSVSTESGVVSQSGTSLTTITTFAPDVTSEYTTTWTTTNSDGSVSTESGIVSQSGSSFTTITTFEPPVVCKRDDVNCGSSIGLSTPYYGNSSQPLSSTKMTDTSATQTVDSSLSSITDATTTQSVNSLETPVPTSGSGNGSNNGSDNGSNNGSNNGSNNGSGSGNGSNNGSNNGSGSGNGFNNGSDNGSNNGSGNASNNGSASGSGSDNGSDNGSDNGSDNGSNNGSNTDNGSNSGSDSGNGIDNGSGNGSSDGSDNGTTNGSGSGGESNNGSGNGSDNGSSPDNGSNNGSNNGSNNGSGDGIGTGSNSDTDNGSGNGSNNGSGSVNGSANGSGNGSNNGSNSGSNSDNGSNNSSGNGSSSDLGSVSGTGNGSNEGSSNESGANNGSNNGAGALPAATLSVVPSPSADSGSTSSASAMVIPNTNGSGKLLNGKVLTLSVLSSMVVVFL
Protein: HDA1 complex subunit 3 (Histone deacetylase complex 1 subunit 3) (Q06623)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for activity of HDA1 histone deacetylase complex. The HDA1 histone deacetylase complex is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- HDA1 complex subunit 2
- Histone deacetylase HDA1
- Histone H3
- Histone H2B.1
- Histone H2A.1
- DNA mismatch repair protein MSH2
- Histone H4
- Histone deacetylase HOS1
- Histone H2B.2
- Histone H2A.2
Sequence:
MDLLRILDTKPIPTIVDATTLGISGNTSGDYWLPTTMSLYQKELTDQIVSLHYSDILRYFETSHYKEDVILESMKTMCLNGSLVATHPYLLIDHYMPKSLITRDVPAHLAENSGKFSVLRDLINLVQEYETETAIVCRPGRTMDLLEALLLGNKVHIKRYDGHSIKSKQKANDFSCTVHLFSSEGINFTKYPIKSKARFDMLICLDTTVDTSQKDIQYLLQYKRERKGLERYAPIVRLVAINSIDHCRLFFGKKFDKNSREYLENVTAAMVILRDRLGTLPPDLRPIYSQKLHYLVEWLENPTVPWPLPDIYPLKQYTSMDVERSLLTEVHFKKSDDQLEDAFSNCSKKRGRHGANKAASSTVAGIEDNITPSFYSTKRLKNDYYTNPLKQDMTQLTGITTADNSSNVNYHLSSGIITHKLIQSMGEVYMDICVQKQELDDYSCLDDLQNDHLKFFSNEDEKIIKEYETVLRTNNENLNRSHELEVENNLKFSQIETLEKDIETLKGSLMAQGETLSKLKDAFVKTDNVQDEIEKEERVSVSRDTEKKYMEQEIKRAVDAIRENEEETHKLNEKQNGLESELKLKFEKSEISTKELNEKIGFLKKELKLENDLNEELVGQLSKTMDNLENLTIPRVRTQNGNTKKKSRAKKPGNV
Protein: Tetratricopeptide repeat (TPR)-like superfamily protein (Q94K88)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Histone acetyltransferase type B catalytic subunit
- Histone H4
- Histone chaperone ASF1B
- Probable histone chaperone ASF1A
- Histone-binding protein MSI1
- WD-40 repeat-containing protein MSI2
- WD-40 repeat-containing protein MSI4
- WD-40 repeat-containing protein MSI3
- WD-40 repeat-containing protein MSI5
- PHD finger protein-like protein
Sequence:
MVEESASASEASVIQTLTEPATEIAQTLEPNLASIEATVESVVQGGTESTCNNDANNNNAADSAATEVCDEEREKTLEFAEELTEKGSVFLKENDFAEAVDCFSRALEIRVAHYGELDAECINAYYRYGLALLAKAQAEADPLGNMPKKEGEVQQESSNGESLAPSVVSGDPERQGSSSGQEGSGGKDQGEDGEDCQDDDLSDADGDADEDESDLDMAWKMLDIARVITDKQSTETMEKVDILCSLAEVSLEREDIESSLSDYKNALSILERLVEPDSRRTAELNFRICICLETGCQPKEAIPYCQKALLICKARMERLSNEIKGASGSATSSTVSEIDEGIQQSSNVPYIDKSASDKEVEIGDLAGLAEDLEKKLEDLKQQAENPKQVLAELMGMVSAKPNASDKVVPAAAEMSSSRMGTVNTNFGKDLESPTVSTAHTGAAGGGAASGVTHLGVVGRGVKRVLMNTTSIESSASKKPALEFSDKADGNSS
Protein: T-box transcription factor TBX5-A (zftbx5a) (T-box protein 5) (zTbx5) (Q9IAK8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for pectoral fin formation. Together with tbx5b, involved in eye and heart development. Required for the looping stage of heart development. May bind to the core DNA motif of promoters.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q99593, ECO:0000255|PROSITE-ProRule:PRU00201}. Cytoplasm {ECO:0000250|UniProtKB:Q99593}. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000250|UniProtKB:Q99593}.
Interaction partners:
- NK2 homeobox 5.
- GATA-binding protein 4.
- Myocyte enhancer factor 2ca
- Heart- and neural crest derivatives-expressed protein 2
- Catenin beta-1
- Insulin gene enhancer protein isl-1
- WW domain-containing transcription regulator 1
- Natriuretic peptide A
- GATA-binding protein 6
- Myosin, heavy chain 6, cardiac muscle, alpha
Sequence:
MADSEDTFRLQNSPSDSEPKDLQNEGKSDKQNAAVSKSPSSQTTYIQQGMEGIKVYLHERELWTKFHEVGTEMIITKAGRRMFPSFKVKVTGLNPKTKYILLMDVVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRIHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSTKEYPVVPRSTVRQRVGSSQSPFSGDVQGLSASGAISSQYSCENGVSSTSQDLLPQSSSYHEHTQDYHCIKRKVEDECPAGEHPYKKPYVESSSSEDDHYYRPLSYSQSLGLSGGAPYRPESSQRQACMYASAPQPPEPVPSLEDISWPGVPPYSVPQMERLPYQHHFSAHFASRQMPEAHGMYASSVSHQCSPSGGIQSPSAGLQGNEYLYAHGLQRTLSPHQYHTVHSVSIMHDWNEAS
Protein: Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) (P23572)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. In embryos, promotes the release of Rif1 from chromatin during mid-blastula transition. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- G2/mitotic-specific cyclin-B
- G2/mitotic-specific cyclin-A
- Cyclin-dependent kinases regulatory subunit
- Wee1-like protein kinase
- G2/mitotic-specific cyclin-B3
- Cell division cycle protein 20 homolog
- Cyclin-dependent kinases regulatory subunit
- Mitotic checkpoint protein BUB3
- Bub1-related kinase
- Fizzy-related protein homolog
Sequence:
MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVRN
Protein: Protein DJ-1 homolog (Q54MG7)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Protects cells against oxidative stress and cell death.
Interaction partners:
Sequence:
MTKKILLLLCKGFEVMEFTPFVDVMGWAREDDNNEDKADIQVVTCGLYNKMVTSTFGVKVQVDVLLGEVVKSLDEFDALAIPGGFENYSFYEEAYSEDVSQLIRDFDSKGKHIASVCVAALALGKSGILKGRNATTYRNSLREHSVRQQQLRDFGANVIADQSIVIDKNVITSYNPQTAPYVAFELLSRLSDENKAKKVKTLMGF
Protein: Forkhead box protein N2 (Human T-cell leukemia virus enhancer factor) (P32314)
Organism: Homo sapiens (Human)
Function: Binds to the purine-rich region in HTLV-I LTR.
Subcellular location: Nucleus.
Interaction partners:
- Protein C-ets-1
Sequence:
MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAVDAARPKATLVDSESADDELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLIQALKKQPFSSASSQNGSLSPHYLSSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFHHPSAVRLQESDSLATSIDPKEDHNYSASSMAAQRCASRSSVSSLSSVDEVYEFIPKNSHVGSDGSEGFHSEEDTDVDYEDDPLGDSGYASQPCAKISEKGQSGKKMRKQTCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKTQNQKQRKK
Protein: Uncharacterized protein C25B2.08 (O74780)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Meiotic chromosome segregation protein C17A2.07c
- Uncharacterized membrane protein C1919.04
- Uncharacterized membrane protein C70.04c
Sequence:
MLPHQNSSYTRQGTNDAQANDMRSPSQLPTSVNIEDPSKLCISSEKLNTPMHNRSRSGIKKHTSVKRSRSFKLFDTLFFGILRLRKQRIRSVKKVRSISSPVLISTTSALALATIEQQPVIGECS
Protein: Zinc finger and SCAN domain-containing protein 10 (Zinc finger protein 206) (Q96SZ4)
Organism: Homo sapiens (Human)
Function: Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187, ECO:0000269|PubMed:38386308}.
Interaction partners:
- POU domain, class 5, transcription factor 1
- Homeobox protein NANOG
- Transcription factor SOX-2
- Sal-like protein 4
- Vertnin
- PR domain zinc finger protein 14
- Forkhead box P1
- Protein lin-28 homolog A
Sequence:
MLGESVPAAVEQEQLGEVKLEEEEAVSPEDPRRPESRLRPEVAHQLFRCFQYQEDMGPRASLSRLRELCGHWLRPALHTKKQILELLVLEQFLSVLPPHLLGRLQGQPLRDGEEVVLLLEGIHREPSHAGPLDFSCNAGKSCPRADVTLEEKGCASQVPSHSPKKELPAEEPSVLGPSDEPPRPQPRAAQPAEPGQWRLPPSSKQPLSPGPQKTFQALQESSPQGPSPWPEESSRDQELAAVLECLTFEDVPENKAWPAHPLGFGSRTPDKEEFKQEEPKGAAWPTPILAESQADSPGVPGEPCAQSLGRGAAASGPGEDGSLLGSSEILEVKVAEGVPEPNPELQFICADCGVSFPQLSRLKAHQLRSHPAGRSFLCLCCGKSFGRSSILKLHMRTHTDERPHACHLCGHRFRQSSHLSKHLLTHSSEPAFLCAECGRGFQRRASLVQHLLAHAQDQKPPCAPESKAEAPPLTDVLCSHCGQSFQRRSSLKRHLRIHARDKDRRSSEGSGSRRRDSDRRPFVCSDCGKAFRRSEHLVAHRRVHTGERPFSCQACGRSFTQSSQLVSHQRVHTGEKPYACPQCGKRFVRRASLARHLLTHGGPRPHHCTQCGKSFGQTQDLARHQRSHTGEKPCRCSECGEGFSQSAHLARHQRIHTGEKPHACDTCGHRFRNSSNLARHRRSHTGERPYSCQTCGRSFRRNAHLRRHLATHAEPGQEQAEPPQECVECGKSFSRSCNLLRHLLVHTGARPYSCTQCGRSFSRNSHLLRHLRTHARETLY
Protein: Gap junction alpha-3 protein (Connexin-46) (Cx46) (Q9Y6H8)
Organism: Homo sapiens (Human)
Function: Structural component of lens fiber gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells (By similarity). They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
Subcellular location: Cell membrane {ECO:0000269|PubMed:30044662}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9TU17}. Cell junction, gap junction {ECO:0000269|PubMed:30044662}.
Interaction partners:
- Gap junction alpha-8 protein
- Gap junction alpha-1 protein
- Gap junction beta-2 protein
- Phakinin
- Gamma-crystallin D
- Beta-crystallin B2
- Beta-crystallin B1
- Gamma-crystallin S
- Gap junction beta-1 protein
- Gap junction delta-3 protein
Sequence:
MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESPSPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKASRASSGRARPEDLAI
Protein: Plastocyanin (O52830)
Organism: Nostoc sp. (strain ATCC 29151 / PCC 7119) (Anabaena sp.)
Function: Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
Subcellular location: Cellular thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_00566}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00566}; Lumenal side {ECO:0000255|HAMAP-Rule:MF_00566}. Note=Loosely bound to the thylakoid inner membrane surface.
Interaction partners:
Sequence:
MKLIAASLRRLSLAVLTVLLVVSSFAVFTPSASAETYTVKLGSDKGLLVFEPAKLTIKPGDTVEFLNNKVPPHNVVFDAALNPAKSADLAKSLSHKQLLMSPGQSTSTTFPADAPAGEYTFYCEPHRGAGMVGKITVAG
Protein: Zinc finger protein OBI1 (Osteoblast inducer-1) (ObI-1) (E9Q8G5)
Organism: Mus musculus (Mouse)
Function: May modulate osteogenic differentiation, at least in part, through the bone morphogenetic protein (BMP) signaling pathway, increasing RUNX2 activation and leading to osteoblast commitment and maturation.
Subcellular location: Nucleus {ECO:0000269|PubMed:30654721}.
Interaction partners:
Sequence:
MVRRRQRLPEVDMGLVSFEDVAVDFTWQEWQELDAAQRTLYRDVMLENYRSLVWLGHCLAKPELISKLEEGFEPWGVAEATEQCLPGVRKWSAPVEKGQQSQEKYLRQVKIIKKNTPDEDKVEVENTYNVDSNCISNMTLKNEVCSRVFFQELVNPLLDVPLPTEAGERQSTEVPHDLNRTQEVLSYPKHFTHHSKDQYSQCCFQYFGPDEAFHTKAILTPEMFYVQETSRTCNNYDKSFDEVTIPAQYMTQLRKQTLGWNICHKIFPNKTELSNHDAMHTGENDDKCDYEKPIINKSLYLTKHQEAHAGIEPQAHKENIKFFCLDAELQTVDPELHGEKQVYECKVSGKTFRHQPEHISQQRPHACERACQAKEHGEAGCDEPALTQHQRLCTEEKACEGKACSKAFHHKSLLPQYQSARADEQQSDCKELMKIYFYVSSPTQHHGPPPPEKPFRCNDCLKTFSHKSQLERHQRMHTGEKPHECKECRKAFCHKSHLIRHQGIHAPEKPYECNECKKSFYLRSQLTLHERTHTGEKPFECKECRKAFSRNSHLTQHQKIHTGEKPHKCKECGNAFARKSHLIQHQKTHTGERPYECKECRKAFSRKSQLMQHETTHTGERAYECKECRKTFYLKAYLTRHQVIHQSEKPFECKKCGKAFSRKSYLTRHQKIHKGQTLSG
Protein: AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (ARID and ELM2 domain-containing protein 2) (Q9LDD4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000255|PROSITE-ProRule:PRU00512}.
Interaction partners:
- Transcription factor bHLH168
- DUF7650 domain-containing protein
- Homeodomain-like superfamily protein
- TRF-like 10
- Nuclear transcription factor Y subunit C-7
- Early nodulin-like protein 1
- Transcription factor bHLH155
- Ethylene-responsive transcription factor ERF015
- Emsy N Terminus
Sequence:
MGSFNDTSCSYVDVEIKYVDECEERLRRLFDQALLVFLEEEGSIKPLPAVIGDGKNVDLFKLFVLVREREGFDTVSRKRLWEVVAEKLGFDCSLVPSLILIYLKYLNRMEKWAVEESRIVNWDNKDSEKKGCYSGMLHELGNGFKSLLDNGKCQKRNRAVAFGCNHMEESCSEFDRSRKRFRESDDDDKGVGLSSVVIREETVVCAVEEGLSDFSLEKRDDLPGMLKWLALVATSPHDPAIGVIPHSSKWKQYNGNKCWLQVARAKNSLLVQRDNAELRYRYHPFRGHQNIHHPSMYEDDRKSIGRLRYSIRPPNLSKHCSSSCCNGSSLVSLSKSRSTKCRKLTIIASERAGLTAGTSRARKRNKAEIPRRCIKVGHQHQAQVDEWTESGVDSDSKWLGTRIWPPENSEALDQTLGNDLVGKGRPDSCSCELSGFVECTRLHIAEKRMELKRELGDDFFHWRFNQMGEEVCLRWTEEEEKRFKDMIIADPQSFWTNAAKNFPKKKREELVSYYFNVFLINRRRYQNRVTPKSIDSDDEGAFGSVGGSFGRDAVTSSGSDVMICAQNRQCEDY
Protein: General odorant-binding protein 56h (Q9V8Y9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid (By similarity). May function in both olfactory and gustatory systems.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- GH25962p
Sequence:
MKFTLFCIALAAFLSMGQCNPDFRQIMQQCMETNQVTEADLKEFMASGMQSSAKENLKCYTKCLMEKQGHLTNGQFNAQAMLDTLKNVPQIKDKMDEISSGVNACKDIKGTNDCDTAFKVTMCLKEHKAIPGHH
Protein: SERF-like protein C1705.02 (Q9UTF0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MSRGNQRDVDRARNLKKSQASKKKQAGDPTKRLEAQAEIMRAKQRAADERKAAEANGGSKGKK
Protein: Stabilin 2 (Stabilin-2 precursor) (C6GHV6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MPFLLDVVCGGLILLLGTEILWVAGAQKRCDKDITMVTKSKCHSCSLSHLAKCPNGYAKMPPGTSDRDCRYYVTPAFSISGCSFNCFKEVVEPQCCRGYWGNDCMECPGSASTPCSNNGVCSDGIAGNGTCTCASGFTGAACEECKTDLYGPTCSNVCRCKNGLCSSGLKGTGECTCFSGYTGLDCAQELPACAALQCGPDSRCIEEMLTGQLVCKCKPGYQGDGVQCTSINPCLRSVCHANAVCAHTGPNKHVCTCTEGYSGDGRVCMPIDPCQTNLGNCTSGSTRCVYDGPGKAHCECLKGFEKFVEGQGCSIIDLCKPDSCHKYATCATAEPGTVECNCREGYIGNGKICFGDIIQQLNEMNSKPGGKWTGQLSSAITLFNQVTGWFLTARGPFTVFVPVNKAFKGTSVKSLLADEMKARYLAKLHVVAGEVNSESLKKGILFHTLTGMGAESMIDAEQVKIRLHGSRKKGALVESDIFASNGMIHLIDKLMDAVPSTVISEKEESLLEILSKNGKFSQFKSLLEKTNVATVLEEDGPYTLFAPTNVAFALMKPDYLAYLKSEEGKTKLLELMRNHIVATTPLSAYVIVSNPRAVTMAEQILTFNVTTAGQILVNGESVIELDVEAKNGRLHSLEGLLIPPSIEPILPHRCDIIKPIKYMAPCVSCTLISKSTCPTGESLKAYRRGCVFNKKQLGLSLPSIGCSHICNDTKTTPQCCKGFFGPDCSPCPGGFTTPCSSHGTCSEGIDGNGTCQCEPKFKGSRCQYCADSNKYGPNCDKTCWCIHGTCDNHPEASGKCKQGSCKDGYTGEYCELQTQPCGPNQPCHAHANCVSNKGAFTCVCKPGFQGDGYMCMESDPCALPHRGGCSKNAICIKTGPGTHKCKCLSGWREDGDECQAINNCLDPSRGGCHPNATCIYVGPGQIDCACKSGYHGNGRECEPVNQCVEQKGGCHFLATCQFLNPDGWHCVCEDGYAGDGKICYGTLLQEVSTNPDLLGFNQWISKAELSQLLSERENLTLFVPSAQAIEKMSKEDKDFWMTPSNLPSLVKNHILSGSFTLSDLNTSPSPPPRLVSLLKRTLPVYSTNDTTIVAGGKITFGDMAAKNGVIHLIDTVLIPEQQMSEGLLQVLKKRSDLSLFYGSLLNHNLTNEMEESLGFTVFAPTDNAIQDYLKRTGKESLDLNVTMYHIILTEILKDVDLVDGLYKDTMLGFQYQLGFFRQDKRLLVNEAEVNVTDLETSKGVIHIISAVLNIPSNRCDKATSILFSGRCMDCFQTIINPCPSGTKKVMSRKRRCMYSRVLHGDTLLTIGCKFSCEKMTIERICCSGHYGINCEKCPGSEDQSCFGNGICKDGINGTGVCLCNQGFNGTACESCQPGKYGIHCDQECKCVHGRCKDGIDGDGSCACDLGWRGVNCDIAIKSDMCGGKCHSSANCLVNVVDSSYYCSCAAGFQGNGTYCEAIDACAERNGGCSAHAVCKRTLPGRRICMCHPGYEGDGKVCTSINPCLDGVNGGCHADSNCIHTGPNKTACHCKEGFYKDGKNCELINLCKEKNGGCHRAAICTMTGPLQRNCTCHAGYVGDGEICKYTLQRELPIGTARTAFVKAMFKNRIYELDTRGPFTVFAFRSENYKNQSIDLLKRTPENTRIMRYHIVCCRTLLPQDLMQPRNLTTLSGDILSITYSENTIYINNKAKVLFSDIESSNGILHEIDSVLVPPGLEIREDKKQDIIPRNFSEVASANGFKTFFKLLEDTDTLKLVMDPIHQPVTLFMPTDDAMSALSQEQKDFLYAMHNRDKLSEYLRYHILRDTKLMASELIYASSLKTQQGSDLSVACMGEEQIGELYVNHKGCRIVKRYLDFNGGMIYGIDCLLNPPSLGGRCDHRQTIDFTLACRSCGSSIMDCPLGSKPGGEQECVLPDSVISRGSKCQSTCKVVVWKPKCCSGYYGRDCLACPGGPQSPCSNHGKCDEDHLGNGTCTCDTGFTGVACESCLDGHFGPDCKACNCTEHGSCDEGLQGTGSCFCEEGWTGPQCENKLADGPVCKYWNGGCSKDAKCSQKGEKVSCACLQGFSGDGFVCTPIDPCVDGENGGCHEHATCTMTGPGKRKCECKDSYVGDGIDCEAKVLPVNRCLVDNGQCHSDAQCTDLHHEDKTLGVFHYRSTNGTYKLNYTMAQEACKEAGSTIATYMQLSYAQQAGYSLCTAGWLDKARVAYPMSFSSPRCGSGHVGIVDYGVRNNLSETWDTFCYRVKDVQCKCKTGYIGDGFSCIGNLMQVLSATPTLSNFLSQILNYSTSASGKAFVNRLRNITIQSTLFVPDNDGLYSNQTLSGRDIEHHLLDGRALILQALINVTHVRTRLGSSLTITGVPDLQNPQKMTSSGYINDRYVIDSNIFASNGVIHVLQGPLKAPPPPTPSFHPAHQAGLGIGVLGLIILIVVAGFVGYNFYTHKTKPFQFYYFKGDEGEDVTPTESSPNISNPVYDAAPATKEQPPTEEDKHQVISSGVFELLQDS
Protein: DNA polymerase sigma, putative (Q57VP5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ATP-dependent DEAD/H RNA helicase, putative
- Poly
- Nucleic acid binding protein, putative
- polynucleotide adenylyltransferase
- Guanylate kinase, putative
- Guanylate kinase, putative
Sequence:
MKDRSAAVHVGSEDVPTARARGAARNKATSSKNRPGRTPICGKDAEENALADEPAKPTSPVAVDSSDAAVDRCGSVSTRNRAGDAITNKRSKVVDIPPPAPSVGLFSKFQERRGDFSSDWMLLQEENAANQPSEPPIAAELVMKLRERQAQMQISRDEVTLKTTGSSAVKNRDEGRLEALNEELRKQGADDGKSDSDVEYVPQEDTRGYRSLKQQGGEETTVVGSAVAAPSTNSDEAEKGFLDDFLGFSKGDSEKNADSRYAVQATVTLKNGKCVLASDEVSSGQGGYDPGHSYLGEETRSVPLWCVGRLTGQKEYAKDAAIALHQEICDFVKFHQPTEAEIAIRCLVEAEVVTIAKQLWPKCEPVVFGSMATGLLLPLSDVDITILNVDVPTEEALRLLAREISLSGICNTAYPQLVLKAKVPLLKFQHCGSLLDVDISINARDGPRNTLIVIDLLKHYREAEPLIVVVKYFLHQRGMDEPYHGGLGSFALTLMAISFLQQHPIYTGSPDQRLYCGLGRLLVDFFRYYGMYFRYDRCGLSVVGTGRCFKRTDVCASSVRPMTNGANSSLGRGGPQSGPPQVLLEDPGCPENNAASSLRNFNVIATSFTHAFRALTAVFEPNRRPGSSSPDALHIDQRPTLLSRILHVDGESVKRRQAIIEAHGSLLQDPNGRLVLQQVVDEHKQRRERMLENVSLLSCPPTSDRLVSHKRPREDSNEDKFSKSRRGDSCSSNDSSVRTARSLTRR
Protein: G-protein coupled receptor Mth (Protein methuselah) (Q9GT50)
Organism: Drosophila yakuba (Fruit fly)
Function: Involved in biological aging and stress response. Essential for adult survival (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MKLFWVKRLLRISTVVVTLLLLQRTNAAIPDCDYYDTVDISAAQKLPNGSYLFEGLLVPANLTAEYEFTILPDDSKQKVDKHIRGCVCKLKPCVRFCCPHNHIMDMNVCAGDMTEEELEVLDPFLNVTLDDGSVVRRHFKKELIVQWDLPMSCDGMFSLDNREKTDQYTLFENGSFFRHHDRVTLNKREYCLQHLTFVDGNESSIRIAPHNCLISPSRMGQTVVMITSLVCMVLTITVYLFVKKLQNLHGKCFMCYMVCLFMAYLLLLLNLWQMSQNFCITAGFLGYFFVMAAFLWLSVISLHLWNTFSGSAHNANRFLSEHRFLAYNTYAWGMAVVLTGITYLADKVVENEDWNPRMGFGGHCWICTQSWSAMLYFYGPMVFLIAFNITMFILTANRIIGVKKDIQKFAHRQERKQKLNSDKQTYTFFLRLFIIMGLTWSLEIGSYISQFNQTWSNVFLVADYLNWSQGIIIFILFVLKRSTLRLLMESIRGEGEEVNDSEEEISLENTKYDRNVL
Protein: Polyamine oxidase (A0A8I6AEP5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MAARGPRVLVVGGGIAGLGAVQRLCHHRAAPHLRVLEATACAGGRIRSERCFGGVVELGAHWIHGPSQGNPVFQLAAEFGLLGEKELSEENQLVETGGHVALPSVSCTSSGTSVSLELVTEMGSLFYGLIDRTREFLNESETPMASVGEFLKKEISQQVANWTEDENTKRLKLAVLNTFFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCTLSGGYQGLTNCILASLPKEVMVFDKPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPLPAKKAEAIRKLGFGTNNKIFLEFEEPFWEPDCQFIQVVWEDTSPLQDSPLSLQDTWFKKLIGFLVLPSFESSHVLCAFIAGLQSEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVLRSRWHSAPYTRGSYSYVAVGSTGDDLDLMAQPLPADGTGTQLQVLFAGEATHRTFYSTTHGALLSGWREADRLIGLWDSQAEQSRPRL