wanglab/gogpt-training-data huggingface dataset:
Protein: Endoplasmic reticulum-Golgi intermediate compartment protein (O95330)
Organism: Homo sapiens (Human)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU369013}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU369013}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000256|RuleBase:RU369013}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU369013}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU369013}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU369013}. Golgi apparatus, cis-Golgi network membrane {ECO:0000256|ARBA:ARBA00004257}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004257}.
Interaction partners:
Sequence:
MSVAFSCCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFAHLPLSTSHPEEN
Protein: CBL-interacting serine/threonine-protein kinase 23 (EC 2.7.11.1) (Protein LOW-K(+)-SENSITIVE 1) (SNF1-related kinase 3.23) (SOS2-like protein kinase PKS17) (Q93VD3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium-dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it from a low-affinity nitrate transporter to a high-affinity transporter. Confers tolerance to low potassium conditions. Involved in drought sensitivity and leaf transpiration.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16814720, ECO:0000269|PubMed:17922773}; Peripheral membrane protein {ECO:0000269|PubMed:16814720, ECO:0000269|PubMed:17922773}. Note=Associated to the plasma membrane when associated with AKT1, CBL1 and CBL9.
Interaction partners:
- Calcineurin B-like protein 9
- Calcineurin B-like protein 1
- Potassium channel AKT1
- Protein NRT1/ PTR FAMILY 6.3
- Calcineurin B-like protein 3
- Calcineurin B-like protein 2
- Potassium transporter 5
- Calcineurin B-like protein 8
- Calcineurin B-like protein 10
- Ammonium transporter 1 member 1
Sequence:
MASRTTPSRSTPSRSTPSGSSSGGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFENADVSLDDVDAIFDDSGESKNLVVERREEGLKTPVTMNAFELISTSQGLNLGSLFEKQMGLVKRKTRFTSKSSANEIVTKIEAAAAPMGFDVKTNNYKMKLTGEKSGRKGQLAVATEVFQVAPSLYMVEMRKSGGDTLEFHKFYKNLTTGLKDIVWKTIDEEKEEGTDGGGTNGAMANRTIAKQST
Protein: Candida glabrata strain CBS138 chromosome I complete sequence (Q6FR25)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Nucleoporin NSP1
- DnaJ homolog 1
- GrpE protein homolog
- Iron-sulfur cluster biogenesis chaperone, mitochondrial
- Candida glabrata strain CBS138 chromosome K complete sequence
- Candida glabrata strain CBS138 chromosome H complete sequence
- Candida glabrata strain CBS138 chromosome I complete sequence
- Mitochondrial import inner membrane translocase subunit TIM44
- Heat shock protein homolog SSE1
- Transcription factor
Sequence:
MLGARRIVQNARVCKRLQSTKVQGQVIGIDLGTTNSAVAVMEGKVPKIIENAEGARTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHTNGDAWVEARGQRYSPAQVGGFVLNKMKETAEAYLGKPAKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKADAKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIVLLREIVSRFKAESGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTEPLIKKTIDPVKKALKDANLSTSDISDVLLVGGMSRMPKVVETVKQLFGKEPSKAVNPDEAVAIGAAIQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFNLSGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDASITVAGSSGLSDAEIEQMVNDAEKFKSQDEARRQAIETANKADQLANDTENSLKEFEGKLDKAESQKVKDEVAALKELVARVQAGEEVDAEQLKTKTDELQTSSMKLFEQMYKNQGNDGNSNSGSSENPENKQ
Protein: EP-cadherin (C-cadherin) (P33148)
Organism: Xenopus laevis (African clawed frog)
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Interaction partners:
Sequence:
MGSTRLRNASVWLCGLLCLLQVVPSINADVSGCKPGFSSAEYIFSVNRRELERGRKLGKVNFSDCTTRKHGLYDVGDSRFRVLPDGTVLVKRHVKLHKDTKFTISTWDARGIKHSTNIAVASKRHRSGEEAHSRSSKLPVLTFPETHTGLKRKKRDWVIPPIKVSENERGPFPKRLVQIKSNKDRFNKVYYSITGQGADNPPQGVFRIEWETGWMLVTRPLDREEYDKYVLSSHAVSENGSPVEEPMEITINVIDQNDNRPKFTQDVFRGSVREGVQPGTQVMAVSATDEDDNIDSLNGVLSYSILKQDPEEPIPNLFTINRETGVISLIGTGLDREKFPEYTLTVQATDLEGAGLSVEGKAIIQITDANDNAPIFDPKTYTALVPENEIGFEVQRLSVTDLDMPGTPAWQAVYKIRVNEGGFFNITTDPESNQGILTTAKGLDFELRKQYVLQITVENAEPFSVPLPTSTATVTVTVEDVNEAPFFVPAVSRVDVSEDLSRGEKIISLVAQDPDKQQIQKLSYFIGNDPARWLTVNKDNGIVTGNGNLDRESEYVKNNTYTVIMLVTDDGVSVGTGTGTLILHVLDVNDNGPVPSPRVFTMCDQNPEPQVLTISDADIPPNTYPYKVSLSHGSDLTWKAELDSKGTSMLLSPTQQLKKGDYSIYVLLSDAQNNPQLTVVNATVCSCEGKAIKCQEKLVGGFDLPIILVILGSVLALLILFLLLLLFLKRKKVVKEPLLLPEDDTRDNIFYYGEEGGGEEDQDYDLSQLHRGLDSRPDIMRNDVVPTLMPAPHYRPRPSNPDEIGNFIDENLDAADNDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSNSNDEHDYNYLSDWGSRFRKLADMYGGDDDEE
Protein: Trafficking protein particle complex subunit 31 (TRAPP subunit 31) (Transport protein particle 31 kDa subunit) (Q03337)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation.
Subcellular location: Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Preautophagosomal structure.
Interaction partners:
- Trafficking protein particle complex subunit BET3
- Trafficking protein particle complex subunit 20
- Trafficking protein particle complex II-specific subunit 65
- Trafficking protein particle complex subunit 33
- Trafficking protein particle complex III-specific subunit 85
- TRAPP-associated protein TCA17
- Trafficking protein particle complex II-specific subunit 130
- Trafficking protein particle complex subunit 23
- Trafficking protein particle complex subunit BET5
- Trafficking protein particle complex II-specific subunit 120
Sequence:
MSQRIIQPSASDQQFPGKSDGYEYTVGPKQAITSEASTTYIPSRIYSESLLFKRQEASLSAMAFLFQEMISQLHRTCKTAGDFETKLSDYGHNIGIRLLELLNFRASVSPSSLPRASAFLSQNESSSKLSNASNSPGMLANSSTATSASANERLQEKQTESLSNYITKMRRRDLKILDILQFIHGTLWSYLFNHVSDDLVKSSERDNEYMIVDNFPTLTQFIPGENVSCEYFVCGIIKGFLFNAGFPCGVTAHRMPQGGHSQRTVYLIQFDRQVLDREGLRFG
Protein: CCAAT-binding factor domain-containing protein (Q585I3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- KRR1 small subunit processome component
- PIN domain-containing protein
- U3 small nuclear ribonucleoprotein
- Bms1-type G domain-containing protein
- 40S ribosomal protein S13, putative
- U3 small nucleolar RNA-associated protein 6 N-terminal domain-containing protein
- U3 small nucleolar RNA-associated protein 18
- HEAT repeat-containing protein 1
- Uncharacterized protein
- NUC153 domain-containing protein
Sequence:
MEKEFTKALQSCDKCSTFHDLCDCFDATVRPLVENCLCSALLKPVRDHVSPNECNPQVSQLRDVLCNIRGGSDDVWFFLYRTAGSLLSRFTKKRMRNDKCNVSTLAVNVFVLFYGRALPDLSKLCLRWDFLRDEKKNYESDEAYVHSNAAERRKLMMSSVLSVFSERAHRHYFTALWMPCLQHAAEAALHVHILHRMGDVILPYLTNPLVVADYLSGCFASGGLIAVLALHGIFILMLDHGLEYPNYYQQLYTLLTPDSFASRHRYDLFRLLDLSLTSLRVPAYIAAAFAKKVARVATLSPAPVLYFVLPFIRKVLQRHQNCLALIHRSTKEAFVPANDDHEVAHSDAGDRAREAGRLAATLFDGNDPFVPDAPLGESHALHSTLWELTALERHFIPTVPLMVSVFSSPAEDQAPLRYEKTYARLFTSEVTRPISKSQLPTVAYREPESEDGALLFV
Protein: Rho1 guanine nucleotide exchange factor 3 (Lethal at division protein 1) (Q9Y7U5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Stimulates the exchange of Rho1 GDP-bound form into GTP-bound form. Regulates, via interaction and activation of Rho1, beta-1,3-glucan biosynthesis and cell wall integrity during septation. Involved in the regulation of contractile ring assembly.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15546915, ECO:0000269|PubMed:16291723, ECO:0000269|PubMed:16324155, ECO:0000269|PubMed:16823372}. Note=Localizes to the outer area (150 nm) of the contractile ring.
Interaction partners:
- Arrestin family protein 1
- GTP-binding protein rho1
- Cell division control protein 15
- Septation protein imp2
- LIM domain-containing protein C4F6.12
- GTP-binding protein rho4
- Protein kinase C-like 1
- GTP-binding protein rho2
- Rho-type GTPase-activating protein 1
- 1,3-beta-glucan synthase component bgs4
Sequence:
MKLSNELFHRSSKDHGGKSRICLDSSEDTYPPHSSSPPSFQKRLSFSDFSTTRLFSPPFLSKRSNNSPHRFSYSPPQHPASINSRRVASYTVQSSPSRTTYRQLPNEPQNSAAYTTYSSFPNALFDDFSPNNPLDTDPFLTSPGNKQNTVDSFRPLPETPVSPGGSLVHPLPRPPLPSSVSSHSSPYSTTSSTSLYSLYNDISLSCSPEPYLPLSPTRSPARTPSPIRLYSSDALRPQSPLSPSVEYLTPPNPYSLKSDISSTRQLPKIPVQDYASGKISSPLITRTHRRAQSETLFSSCREPWLVGKLYKWCKEEVFTALGGLVHEGVSRREVAQVMATLFTIHIASMEFLIAEIIAKNILGDWINYGLVEVINLEKLQIAFTSNEPPSGSGVLPFLTNGGCYSYICRSRSCPSKYQCYSCRCARNSSLEFTSLPGQSSDTWSIFWNISSLNSLPSSLSKREIARQNNIHELICKESDYVADLNTLAELFRDGIVQQQDAIVPSNRVADFIQSVFGNVESIRQLHSRLFLPQLIMRERLQGPVVSIIGDILLEWIHAAKSSYINYAKQFPLADETYKLECQRNTYFARWLAACRSDPRCRRLDFQHFLQRPTQRLQRYTLELDTILKHTEQSSWDFQLITQAVKELRATCEECDAVIATVLEANRIRDLSYQLLFKNHESVNLELRDPEREFFFEGIVQRRSDSRLDWLDIHLFLLDNYLIMAKARKDKRTNASRYVVSKRPIPLDLLVLSPKMDDFQLKSNTNKFLGSLAGNLPQESLTTKSKRKSKVNLELMFDATAEKNNENSMNSAVFEKSQLYPFTIRHLGAYTASYTLYVESLQLRKLWVEKINVAKKRHSQKINIKNPFALKVVSDVAFQYPPSDLVNGNEPLNSFNEITLVEGSSIDRALNEVAWKHPIVSEELLPEPIAYGDISCIAQFNDYEGHVSVLIATSTGIFLGAFGDSSDIRDWKKISSQRRVTQLGVVEEFDILLELRDKTLYAHKLSRIIEMGLIESKIAVVIGTPHAVSFFKIGKLSEGASVKRERTLVFYKEGLGNTTTIICCEPVIGLGHNYQKTYAFKRKDVTSFRTLDDFHVTANCHSIDCFKYSIALCHNKGIDVLRLDPKLAVGFPSPSVLNDTLFRNRINNSKPLGVFRIHDPSLFACCYQFGAVFVNGEGSMVNKECWFDWIGKPNSVTSCHGYLIAFNDEFVEIWNTRTRKLNQIIQGNDIKYYPSNSDWLANGKYIMFGMVHPQYHDRHLILALNKAKTNSFIIED
Protein: Putative polysaccharide deacetylase (EC 3.-.-.-) (Chitin deacetylase 1) (O13842)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May deacetylate chitin (Probable). Required for spore formation.
Subcellular location: Prospore {ECO:0000305|PubMed:15862318}.
Interaction partners:
- Glutamyl-tRNA
- Chitin synthase 1
Sequence:
MYETRDLTGNAGKPVDTNPWPNNSKIAVSFVVNYEEGGERSLLYEDEGFETFLTEAGLMPFPNRPVRERSIESCFEYGSRCGFWRILNLFKKHKVPFTCWAIGQAVEKNPVVVGAMEEAGCEVGSHSHRWINYEGVPPETEYEHIKKSVQAIQKASPSNSAPRSWYTGRASLNTRKLVCQVYKDLGLPQPFDSDEYNDDYPYWVADPLASKPGAEDDKGLLIVPYTLEVNDMKYAVAPGFCNSDDFYTYARDAFDVLYEEGLEGAPKMMTIGLHCRLTGRPGRFRGLQKLMEHITSKEGVWVATREQIAQAWSAKHPYKA
Protein: Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS) (CII-4) (Malate dehydrogenase [quinone] cytochrome b small subunit) (QPs3) (Succinate dehydrogenase complex subunit D) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit) (Succinate-ubiquinone reductase membrane anchor subunit) (A5GZW8)
Organism: Sus scrofa (Pig)
Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:O14521}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Succinate dehydrogenase flavoprotein subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Fumarate hydratase, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase 1 alpha subcomplex subunit 2
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
Sequence:
MATLWRLSVLCGARGGGALVLRTSVVRPAHVSAFLQDRHTPGWCGVQHIHLSPSHQASSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKVAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL
Protein: ABC transporter G family member 22 (ABC transporter ABCG.22) (Q55DA0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May be involved in cell migration.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- ABC transporter G family member 4
- ABC transporter F family member 2
Sequence:
MDQVSIEMSSTPRPTMVKSKSQLSLRRSLTITFKDLAYSVTVKKKKMQILKGVSGTVTPGELVAVFGPSGSGKTTLLDILANRKESGEISGAVLINGNEIDDDYKRLCSYVVQEDVLLPTITVRETLRFYADLKLPKSWTEKEKHERIEQILEQIGLSHRADAKIGGVLPGGIVLRGLSGGEKRRVSIGCGLVTSPSIVLLDEPTSGLDTTSAMAVMKTLVELTQQKSVTVICTIHQPRSEIFKLFTKIMVLAEGRLVYYGNRPVEHFTEIGFPFPDQTNPADYILDAVTTIKEEGRADEIADRLQSSYLDQANQESSSTLTQSQLGIINASGKRKINAYNNGLFTQFLVLWKRTGLDFIRNPSNCLVRFAVAVFVGLLFGACFSGLGMDEKGVQSRSAVLFYLVINMILQPFASISLFISKRTLFNAERASKLYHTLPYYLALMFFEILACIGTAFILGTITYWFADLNPGADKYFFAMAILTLAHLAGDFFMLIISCITVQVDTSFAVGAGVATIYQLFAGFFVPINALPKSFEWLHWCNFVYYSFEALMHNEFVGETVNCGQLACPTGRDVLINLGLNNRGKGINLIIVSSFAFAFFTMVFLCLHYFHREKR
Protein: SKI family transcriptional corepressor 1 (Fussel-15 homolog) (Ladybird homeobox corepressor 1) (Lbx1 corepressor 1) (Transcriptional corepressor Corl1) (Q8BX46)
Organism: Mus musculus (Mouse)
Function: Inhibits BMP signaling (By similarity). Acts as a transcriptional corepressor of LBX1.
Subcellular location: Nucleus {ECO:0000269|PubMed:15528197}.
Interaction partners:
- Dual specificity mitogen-activated protein kinase kinase 5
- Mothers against decapentaplegic homolog 3
- BTB/POZ domain-containing protein 9
Sequence:
MALLCGLGQVTLRLWVPLPFQSENRIGFLAAGAFLRSGGMEALTTQLGPGREGSSSPNSKQELQPYSGSSALKPNQVGETSLYGVPIVSLVIDGQERLCLAQISNTLLKNYSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGEHKPPKLPENFAFDVVHECAWGSRGSFIPARYNSSRAKCIKCGYCSMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLSDKSATDELSHAWEDVKAMFNGGTRKRTFSLQGGGGGGANSGSGGAGKGGAGGGGGPGCGSEMAPGPPPHKSLRCGEDEAAGPPGPPPPHPQRALGLAAAASGPAGPGGPGGSAGVRSYPVIPVPSKGFGLLQKLPPPLFPHPYGFPTAFGLCPKKDDPVLVAGEPKGGPGTGSSGGAGTAAGAGGPGAGHLPPGAGPGPGGGTMFWGHQPSGAAKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPPYPAAQSQAKAVAAAVAAAAAAAAAAAGGGGPESLDGAEPAKEGSLGTEERCPSALSRGPLDEDGADEALPPSLGPLPPPPPPPARKSSYVSAFRPVVKDAESIAKLYGSAREAYGSGPARGPVPGTGTGGGYVSPDFLSEGSSSYHSASPDVDTADEPEVDVESNRFPDEEGAQDDTEPRAPSTGGGPDGDQPAGPPSVTSSGADGPTDSADGDSPRPRRRLGPPPAIRSAFGDLVADDVVRRTERSPPSGGYELREPCGPLGGPGAAKVYAPERDEHVKSTAVAAALGPAASYLCTPETHEPDKEDNHSTTADDLETRKSFSDQRSVSQPSPANTDRGEDGLTLDVTGTQLVEKDIENLAREELQKLLLEQMELRKKLEREFQSLKDNFQDQMKRELAYREEMVQQLQIVRDTLCNELDQERKARYAIQQKLKEAHDALHHFSCKMLTPRHCTGNCSFKPPLLP
Protein: Farnesyl pyrophosphate synthase (Q7KAK2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDTIGGLPTELVNEQKLKKTSRTLSTLQNHSVPIAARVTVSKDESRDFMAVFPDLVRDITTVTKAYNCSDAAKWFAQVLQYNVPRGKKNRGILTVLTYKNLVPTQDLTPENIKLAQYLGWCVEMLQSFFIISDDVMDNSTTRRGQPCWHKVENVGLTAINDALMIENAMYAILKKHFSHLDCYVALMELFHEITYITTCGQSLDQLNSNRCVSEFTMENYKAIVENKTAYYSFYLPFALALHLAGYKDAEAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGKIGTDIQDNKCSWLAVVAMQRANVEQKQIMVDCYGKEEPAKVERVKELYKELGLPSTYAIFEEESYNMIKTHIQQTSRGVPHQTFLQILNKIYQRDS
Protein: Developmental and secondary metabolism regulator veA (Velvet complex subunit A) (E9RCK4)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity). The velvet complex hat acts as a global regulator for secondary metabolite gene expression (By similarity). Controls the expression of hundreds of genes, including those comprising more than a dozen known secondary metabolite gene clusters. Controls the expression of the gliotoxin gene cluster. Controls the expression of the fumagillin, fumitremorgin G, fumigaclavine C and glionitrin gene clusters. The regulation of the fumagillin gene cluster and fumagillin production is performed through direct control of the expression of fumR. Negatively regulates conidiation. Required for normal protease activity.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:C8VTV4}. Cytoplasm {ECO:0000250|UniProtKB:C8VTV4}. Note=Enriched in the nucleus in the dark (By similarity). {ECO:0000250|UniProtKB:C8VTV4}.
Interaction partners:
- Secondary metabolism regulator laeA
- C2H2 type master regulator of conidiophore development brlA
- Conidiophore development regulator abaA
- Velvet complex subunit B
- Developmental regulatory protein wetA
- Probable DNA-binding protein creA
- pH-response transcription factor pacC/RIM101
- Cell pattern formation-associated protein stuA
- Trehalase
Sequence:
MATRPPLMPPANETESSVSRISREGKKITYKLSVMQQPERARACGAGAKSSADRRPVDPPPVVELRIFESDPNDDLHKTDITFAYNANFFLFATLETARPMAQGRLTGPPTCPVLTGVPVAGVAYLDRPQQAGYFIFPDLSVRHEGRYRLSFHLYEEIKDIKDADKDTPMPDLNSSTNLTKPSAPKAHLNFRLEVKSVPFTVYSAKKFPGLATSTSLSRIIAEQGCRVRIRRDVRMRRRGEKRTDDYDFDDERAFATRSDRYTTPDMYAANSAERARSTSISTTADTSFPYGSDAQRRPSAGDYGFQGAQPYQRSMPAASAAPAPAPVHSPATSAQTSSYQSHLSFGATQSQYPAPQLPPTPQSATPTNTYSPHPSYSHSRNPSNGTEYDATSSGYPYPQPRLPADRPSYSKAALPPLRLEPPKAPNMQTSTDSRSSDANAYPTLSQPPVPRAPTPANHVTSLPPLKVLSGEYSHPSQPNAQSPHHDLGSGKRLLWETNHTLSKRSHEETFGSDERPLHNGMRPDMDQYPSMGRKQPDYGRLPFYTDSRDEMAYKRANGRMVMKILPALP
Protein: Transcriptional activator protein VanR (P74946)
Organism: Vibrio anguillarum (Listonella anguillarum)
Function: Probable transcriptional activator. Binds to autoinducer molecule ODHL.
Interaction partners:
- Acyl-homoserine-lactone synthase
- Two-component sensor histidine kinase BarA
- VieS
- Aerobic respiration two-component sensor histidine kinase ArcB
- Hybrid sensor histidine kinase/response regulator
- TMAO reductase system sensor histidine kinase/response regulator TorS
- Hybrid sensor histidine kinase/response regulator
Sequence:
MYKILRLIQENQQITSHDDLENVLNGLNNLIGHEFFLFGLSFQPTLKTSETLVTDNYPNSWRQQYDESGFMHIDPIVKYSITNFLPIRWDDAKRVNNDGRVIFEEARCNGLKAGFSIPIHGLRGEFGMISFATSDTKSYDLNQQSIHTSQLIVPLLAHNIGNITRYHKDAKPRAVLTAREVQCLAWAAEGKSAWEIATIINTSERTVKFHFSNACKKLGATNRYQAITKAILGGYINPYL
Protein: Meiotic sister-chromatid recombination protein 3 (Q05812)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in the control of meiotic sister-chromatid recombination.
Subcellular location: Cell membrane {ECO:0000269|PubMed:14562095}; Peripheral membrane protein {ECO:0000269|PubMed:14562095}. Note=Cell periphery.
Interaction partners:
- Eisosome protein SEG1
- Eisosome protein 1
- Uncharacterized protein YGR130C
- Sphingolipid long chain base-responsive protein LSP1
- Sphingolipid long chain base-responsive protein PIL1
- Uncharacterized protein YML119W
Sequence:
MVFGFTKRDRRVPDLSRYDYYYQNHEDYNKSPQLSAAAASAASAASPDRTNYSRSHSLVSHAPSIPRQRSSVKSPGRRLSTSSAAPPTSRAAAKQYSQKTYSLRSQRSGEYHLHPPGYTTNGSRMNSMTSGANVRRNYGKNKSTAGNNNDSRANSITVKTTQVTDPSGRTQSITKKTIRKINGYEYVETTTTTKNLVPLGDSQRHFDEFSENYMLQDDDILEEQASDNIHDIIEENETDNEKPYSPVSESHLQDDSELNVEKPDFPLGSYFHHKYSTDVMPLEEESSLSNFSDALDYIPPTHQTSSKYIHNKRKQASTTRRKKRPPAVKNAEAEAKKPLTEAEMYLKALEVAKRNVYHTDAASDNASAPLGSNKSRKSRMGQKMTLRSSSDSPTATANLVKSNVEVQPKRFTSSFFSRNTKSAPHEVHNHSVSTHFKSNKAVDPVPEPKSANTGLTDKEMYDQALKIAQARYYNSHGIQPEAVDNSTTAAKPRQVGVSHLGSTGSIPPNEQHYLGDSEIPVQSEVHEYEPIPLQKTKTTGSSKNKFKTMFDKVLQFSQENYGYQHKKEQGEQTPVTRNAEESFPAASISEGVTTAKPSSNEGVMTNPVVTDSPSPLQQQIDSTTASSNGQSQGNVPTSAVASTTRTRSPELQDNLKSSSSLLQDQTPQRQEDATDPTTSSTNELSAAEPTMVTSTHATKTIQAQTQDPPTKHKKSSFFTKLFKKKSSR
Protein: Protocadherin alpha 11 (A0A0A6YY44)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MLSFQRRGSCTLPPLRWLLLLAAWEAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPVFPLREQRLLISESKQPDSRFPLEGASDADIGENAVLVYRLSQNEYFSLEPPINSKQTKRPSLILKKVLDREKTPELNLLLTATDGGKPELTGTVQLWVRVLDVNDNDPVFDHLEYKVRIMENAAKETLVITLNATDLDEGANGQLVYSLMSIKPTGRHLFTLDEKNGELRVNGTLDYEENKLYEIEVLATDKGTPPMVGHCVVLVEILDTNDNSPEVTLTSLSLPVREDAQPNTVIALISVSDLDSGINGQVTCSLTPNVPFKIVSTFKNYYSLVLDSSLDRERVSTYDLVVIARDGGSPSLSATVSVSVEVADVNDNAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLPHGAVGAGGAVSELVSRSVGSGHVVTKVRAVDADSGYNAWLSYEVQLGTGGVRSPFRVGLYTGEISTTRALDEVDSPRQTLLVLVKDHGEPALTATATVLVSLVESGQAPKSFSQASGRASAPEASLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPMVNEATGGPGKPMLVCSSEVGSWSYSQQRRQRVCSGEVLPKTDLMAFSPSLPPNLGRDERERQESESSHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPEPKKQTQVSFLPRRKGEASQPRQ
Protein: Ras-related protein Rab-9A (EC 3.6.5.2) (P24408)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: Involved in the transport of proteins between the endosomes and the trans-Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P51151}; Lipid-anchor {ECO:0000250|UniProtKB:P51151}; Cytoplasmic side {ECO:0000250|UniProtKB:P51151}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P51151}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P51151}. Late endosome {ECO:0000250|UniProtKB:P51151}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:P51151}; Lipid-anchor {ECO:0000250|UniProtKB:P51151}; Cytoplasmic side {ECO:0000250|UniProtKB:P51151}. Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:P51151}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P51151}. Melanosome {ECO:0000250|UniProtKB:Q9R0M6}. Note=Colocalizes with OSBPL1A at the late endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis. Mainly localizes to late endosomes and partially localizes to Golgi. Colocalizes with NDE1 to membrane vesicles. {ECO:0000250|UniProtKB:P51151}.
Interaction partners:
- GRIP and coiled-coil domain containing 2.
- Pleckstrin homology and RUN domain containing M2.
- RAB9B, member RAS oncogene family.
- VPS18 core subunit of CORVET and HOPS complexes.
- Vacuolar protein sorting-associated protein 11 homolog
- Vacuolar protein sorting-associated protein 41 homolog
- Vacuolar protein sorting-associated protein 16 homolog
- Rab GDP dissociation inhibitor alpha
- Rab GDP dissociation inhibitor beta
- Osteoclast stimulating factor 1.
Sequence:
MAGKSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQTDTVSLHRKPKPSSSCC