wanglab/gogpt-training-data huggingface dataset:
Protein: Probable WRKY transcription factor 58 (WRKY DNA-binding protein 58) (Q93WU7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223}.
Interaction partners:
- UBP1-associated proteins 1A
- Probable serine protease EDA2
- Probable LRR receptor-like serine/threonine-protein kinase At1g51810
- Uncharacterized protein T14D3.50
- Carboxyl-terminal proteinase-like protein
- Pathogenesis-related thaumatin superfamily protein
- Probable disease resistance protein At1g63360
- Putative disease resistance protein At1g63350
- DGCR14-like protein
- Probable lysophospholipase BODYGUARD 2
Sequence:
MAVEDDVSLIRTTTLVAPTRPTITVPHRPPAIETAAYFFGGGDGLSLSPGPLSFVSSLFVDNFPDVLTPDNQRTTSFTHLLTSPMFFPPQSSAHTGFIQPRQQSQPQPQRPDTFPHHMPPSTSVAVHGRQSLDVSQVDQRARNHYNNPGNNNNNRSYNVVNVDKPADDGYNWRKYGQKPIKGCEYPRSYYKCTHVNCPVKKKVERSSDGQITQIIYKGQHDHERPQNRRGGGGRDSTEVGGAGQMMESSDDSGYRKDHDDDDDDDEDDEDLPASKIRRIDGVSTTHRTVTEPKIIVQTKSEVDLLDDGYRWRKYGQKVVKGNPHPRSYYKCTTPNCTVRKHVERASTDAKAVITTYEGKHNHDVPAARNGTAAATAAAVGPSDHHRMRSMSGNNMQQHMSFGNNNNTGQSPVLLRLKEEKITI
Protein: Large ribosomal subunit protein eL13 (60S ribosomal protein L13) (Q54E20)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the LSU, it is probably required for its formation and the maturation of rRNAs.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P26373}.
Interaction partners:
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS25
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein eL18
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein uL22
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL36
Sequence:
MPIHNKVLSNDHFRKHWQMRVRTWFNQPARKIRRRNNRIEKAAKVFPRPIATLKPVVRGSTIRYNMKVRAGRGFTLEELKAAGLTAQYARTIGIAVDTRRVNKTQQSLTLNTQRLKNYQSKLVLFPRKVNAPKKGEATKEEVAKAVQTLKPFTVKSAIAVTCEQTPRKPTEAEKKFSAYATLKAADSKAKTVGIRRKAAEIKAAKAAEK
Protein: Surfeit locus protein 2 (Surf-2) (Q15527)
Organism: Homo sapiens (Human)
Interaction partners:
- Surfeit locus protein 4
- Surfeit locus protein 1
- Surfeit locus protein 6
- Endoplasmic reticulum-Golgi intermediate compartment protein 1
- Mediator of RNA polymerase II transcription subunit 22
Sequence:
MSELPGDVRAFLREHPSLRLQTDARKVRCILTGHELPCRLPELQVYTRGKKYQRLVRASPAFDYAEFEPHIVPSTKNPHQLFCKLTLRHINKCPEHVLRHTQGRRYQRALCKYEECQKQGVEYVPACLVHRRRRREDQMDGDGPRPREAFWEPTSSDEGGAASDDSMTDLYPPELFTRKDLGSTEDGDGTDDFLTDKEDEKAKPPREKATDEGRRETTVYRGLVQKRGKKQLGSLKKKFKSHHRKPKSFSSCKQPG
Protein: Translocator protein (Peripheral-type benzodiazepine receptor) (B1AH87)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004225}.
Interaction partners:
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGW
Protein: Protein kibra (Q9VFG8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signaling pathway.
Subcellular location: Cytoplasm. Apical cell membrane. Note=Localizes at the apical cortex of epithelial cells and cytoplasmic, punctate.
Interaction partners:
- Protein expanded
- Moesin/ezrin/radixin homolog 2
- Scaffold protein salvador
- Serine/threonine-protein kinase hippo
- Serine/threonine-protein kinase Warts
- protein-tyrosine-phosphatase
- Protein crumbs
- Cyclin-G-associated kinase
- Ubiquitin-ribosomal protein eS31 fusion protein
- Death-associated inhibitor of apoptosis 1
Sequence:
MPNLQQTASQSQHHLHPHHLRPQQQQQQHHHHHQQQQQQQHTHHQQQQQHHSDFPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGDELPMGWEESYDPNIGPYYINHLAQSTQLEDPRQEWKTVQEQMLSDYLSAAQDQLENKREMFDVKQQRLLWAQEEYNHLKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVHQLKQELTHITNDISYTERGMNTLYSVGEKINARENGCYDIAEVHAIREEMLKVHKSLVSGEKVREELMRSLVQIKNELGRQQISEENSDLASPFDRVCVASQTDLCGSSGENLNGGARFAEMAKTKWQYAEWRKHIKKLQQQLADHVERIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQTRHKLEEDLKEAYEANNTCVANRLRFHEEKQLLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTASSKSALSFTDIYIDPFAVDSPIDVVDLRRRSQRLFQQHQQQRLHPVHPVLQQQQSAEVTLSPRSSLSMETPPASPMKYNAGADQTPQALKEEPTYANALPAPPAYTAPPPVPISGVRARPYDLDSTVLDCMMLEAKLQKLNMGTPLNLAVAPLSPISEKPSLLDLPQEMLSRSSSTSNTRSVSAAVSNESVAGDSGVFEASRAHLPRKELAQVQIGLKYLKQEGVLVVSLERANNLLALWTASADNSQVYLRAALLPNSLTSIRTKALGDFQKPVFNDTFAVPITLDKLLTKSLQVTVVTMTGQKEEIIGTVQISMAEFNPEDSTLKWYNVLSSKFIPSFESLDIPSTSAAAAAAAVAASNAPNPGNNREESSDESTITSSQTSTLTRNQAPCMELQEQMAAELLGLGPLNEPECSDDDDDDEEEELDDKQLVSDVGLMNSSSMLHAYLQNMKQEFADKETNTDRAYLPEKSRGQSQLMDDRPVKRSQTFTPSEAFSKNRYNCRLNRSDSDSAMHCGVAPHTFQRGAAERRSLRFHSKAPKSVTKLHHTHIPRTSLDLELDLQAQHSKLYFLNDQIAKLQNLKEVLQKACENKDPLVAAWAIENEEFQRLVARADPAKCPEERQLQKLLMKTAKEIHKLRKTKVPKGCPDLVSFKEKITFFTRKGLSVPELPSEFTLPEANPIEEEEEEEDENEFYNSAETAIAINTALVASSNRNKNLSEHPHRATSGAVPKIPAPVVTPAATPAATPAATPAATSAATPAATPVVSPAAQPDAKPADAPIPVASNDAEQQRFDYVVDRNYGVEV
Protein: Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Suppressor of RNA polymerase B 6 homolog) (O14010)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 6
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 8
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 11
Sequence:
MSSDSFQRQLVQRTNTLNSSIDNATLTILSRFQDILDIAINEGKDKYTVAPEVYQIECHTVSMVRAVEQLLDVSRQIKSYWLTNSLSTSFPTVDYSEPDLEKVKRTLTKLQNHLLEVSLIEPEASETTEAPTVSDT
Protein: GH03570p (Q95TF1)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNNVPHKFRQVCRLCLTLVNECDVAVLQIYDNSSHNNSAPDRISADFRGVANRANCFCSALSPNPCSCIVDNPLSANKNERRNQGTPVPVPIPIPVSVPVPVPSQQIQSQTLHHHQNQTKIHYTPSVPSAADAKSSERERQCQLESDIAERSTVFKSQSSSDHEHIEYSGETPSPSASLSQSQTKSEPMREEEEHQHNHNQQSGREETSVNTTNISGTDNYGKEHGRDDSSSPHLTFQIFNCLSIKALPNDGLPNVVCGDCRQKLDSFEKFRTMAHNSQIALKEFLNISKNLRPDPNDLETKLDAILKASSEAIAAKALTELSTFSKVKYDHSKLDSSIQPGLDRKIEISNQEMPAHSLYPSLFKSITMKSDQKSKAMSGSSHSQFDSKLQKDSDIEKYENLQQQLETAAVLMDIKKKNSNFPSMFESAISVFFCSCRYKY
Protein: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Q9VVT8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Fatty acid synthase
- Lysosomal thioesterase PPT2 homolog
- Palmitoyl-protein thioesterase 1
- long-chain-fatty-acid--CoA ligase
- Fatty acid synthase
- carnitine O-palmitoyltransferase
- Long-chain-fatty-acid--CoA ligase heimdall
- Very long-chain-fatty-acid--CoA ligase bubblegum
- Fatty acid synthase
- Sterol carrier protein 2
Sequence:
MTPEKSVMAYVNHLIVSNFSYFWDEIDGYLYYLGGTLGTLTLGSLAASVAYYFATRPVPERPLVPLENQSPLLEGPEQIHVSKFYKESKNGKFVSYITENVRTLYQTFREGAYASNNGPCLGWRETLTSPYQWINYDEALLRAKNFGAGMLALGARPKQLIGIYSQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDDGKAAMLLEKAPRSLKIIVAIKPIRQTTLERARSRGIQIFSFIDVEKLGAKGNHPEVPPTAEDLCTVCYTSGTTGNPKGVMLTHGNVVAGVCSVILQMGDHRIRAGDVMVSFLPLAHMFERCCENGMYYVGGCVGFYSGDIKELTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASGLKRGLFNMAMRAKEKEIARGVLRRNGCWDKLVFKKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAITLTVQGDHVPNHVGPPVSCNAVKLVDVPEMEYFANQNTGEVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVYVYGESLKSCIIAVVVPDTDVLKQWATENNVRGTLSVLCNNKNVKELIMNDMLNWGKQSGLKSFEQVKDIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMYKHLD
Protein: At1g75700 (F10A5.27) (Putative transcription initiation factor) (TFIIF-beta 2) (Transcription initiation factor IIF, beta subunit) (Q9LQZ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription initiation factor IIF subunit alpha
- DNA-directed RNA polymerase II subunit 4
- General transcription and DNA repair factor IIH subunit TFB2
- Pentatricopeptide repeat-containing protein At4g30825
- DNA-directed RNA polymerases II, IV and V subunit 11
- Transcription initiation factor IIA subunit 2
- General transcription and DNA repair factor IIH helicase subunit XPD
- Transcription initiation factor IIE subunit beta
- Transcription initiation factor IIE subunit beta
- General transcription factor IIH subunit 2
Sequence:
MEDIHNLDIEKSDRSIWLMKCPVVVDKAWHKIAASSSSSFASSDSPPDMAKIVREVDPLRDDSPPEFKMYMVGAEYGNMPKCYALNMFTDFVPMGGFSDVNQGCAAAEGKVDHKFDMKPYGETIEEYARLCRERTSKAMVKNRQIQVIDNDRGVHMRPMPGMLGLVSSNSKEKRKPPPVKQTEVKRTRRDRGELEAIMFKLFEGQPNWTLKQLVQETDQPAQFLKEILNELCVYNKRGSNQGTYELKPEYKKSAEDDTGGQ
Protein: Thioredoxin superfamily protein (F4IIH6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast stroma {ECO:0000256|ARBA:ARBA00004470}.
Interaction partners:
Sequence:
MAISSSSSSICFNPTRFHTARHISSPSRLFPVTSFSPRSLRFSDRRSLLSSSASRLRLSPLCVRDSRAAAEVTQRSWEDSVLKSETPVLVEFYTSWCGPCRMVHRIIDEIAGDYAGKLNCYLLNADNDLPVAEEYEIKAVPVVLLFKNGEKRESIMGTMPKEFYISAIERVLNS
Protein: Ceramide-binding protein svf1 (Survival factor 1) (Q09885)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May be involved in the response to oxidative stress.
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:Q05515}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q05515}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q05515}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q05515}. Cytoplasm {ECO:0000250|UniProtKB:Q05515}. Nucleus {ECO:0000250|UniProtKB:Q05515}. Note=Localizes to the interface between the cis-Golgi network and endoplasmic reticulum exit sites. {ECO:0000250|UniProtKB:Q05515}.
Interaction partners:
- Oxidation resistance protein 1
- Meiotically up-regulated gene 113 protein
- Uncharacterized protein C16C6.04
- Uncharacterized protein C56F8.02
- Uncharacterized protein C1494.08c
- DnaJ protein homolog xdj1
- Dolichyl-phosphate-mannose--protein mannosyltransferase 1
Sequence:
MKAWLQSSISYYTGTAEPVYGPEAIQPVTASVQGINPFHRLEADDFKWSTPSSSHVETQVFYIKPNEGDYMCFVQLIHSNLGSWTTTAQSTCRIFDLKHPENDLWTSTNMDQFSFENDKTSFVAKNCSVVLEDQKRYRIRASINMDSIIDITVHQDAPPFKIGEDGNSTYGTDPSKPWASMKHTFWPRTRVEGSIVARGRVVDVTGPGMFVHALQNGKPHHLASSWEFALLQHKKFTAIMMQFKTPPSYGSTIVNIGGIAMKDKIISATVDNTIEHVETTLDPDTEWHEPTRISYEWDGKDAETYTEDIHLSVDAPLGRRLQRIDVLAEIPSWLKGFVHGVSGTKPFIYQYFSPVKFTLKMGDEVIEDEATLFNETTFIS
Protein: HpaA protein (Q3BYL2)
Organism: Xanthomonas euvesicatoria pv. vesicatoria (strain 85-10) (Xanthomonas campestris pv. vesicatoria)
Interaction partners:
- HrcD protein
- HpaB protein
- HrcQ protein
- HrcS protein
- HrcR protein
- HrcV protein
- HrpD6 protein
- Flagellar biosynthetic protein FlhB
- HpaC protein
- Avirulence protein AvrBs2
Sequence:
MIRRISPGTLRPSVSIEHGGSHHHGDHHADASGTSAGSPTDIAARAPRLRPAPPRRRRRGIRSLDGQEDEFDANEQEEIEAKRECALRGRVSVAITPAQSREHGQGDQHGGDRSTHTDDPQAGPWHSAAPAQLSDSIRTCIDAIVDRYVTRRDADPVAKRHALAAALVELRAVGVSHPAVAPLTATIWRLMREHLRAYDKATAAENLLALRTRLLELMPSELEPVPALRNFHLLLPLILLNAEKPRRRVDRTHAITRLNTLLIEQPQQAAQEVRP
Protein: Renin-2 (EC 3.4.23.15) (Angiotensinogenase) (Submandibular gland renin) [Cleaved into: Renin-2 heavy chain; Renin-2 light chain] (P00796)
Organism: Mus musculus (Mouse)
Function: Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P00797}.
Interaction partners:
Sequence:
MDRRRMPLWALLLLWSPCTFSLPTGTTFERIPLKKMPSVREILEERGVDMTRLSAEWDVFTKRSSLTDLISPVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAQFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHLLGGEVVLGGSDPEHYQGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
Protein: ubiquitinyl hydrolase 1 (EC 3.4.19.12) (E9QIU2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MQKALKKYFVSMDEYLASIGLYRKMMARDASCLFRAVSEQLYYSQNYHQRIRKECVNFIRANRCNFEPFVEGSFEKYLERLEDPKETVGQVIIKALSLLYRRCFVIYRYPGKPPTEIAEEDNLPKILLCCSNNGHYDIVYPKSYPVDAAVCQALLYELLYTRVLGVEDNEIQAALEGFKGGGRRYRNSHSMCSEDASYDTPEDRSQREDWESRGHCRFDDRPRVGAEDQKVTEGSGKLALPYKVLKALEPELYRNVEFDVWQDSRKELQKTDYMVFAGRQYFLGDKCQVRLDPKGKYYNAFIQEVGTHSTAVTVFIEELGEKHLVSLTNLKPVNPVPAWNITPSRKGNSYSHAEQYPGELDPELRGRRRFFKKPRGKEMLMAVSFSRPQPGLPPRLQPGPGNIHPVRSPGVHSPAPPPPGLIYEHYRPHPPPRQPRGYGPPSSARFLNRHHLIGPDMAYYPSPSKRCYQSFDNYSFRSRRSRRQMHTLNKECLSCVPEPGEETQDMEGSITFYELEETDEGAFSPISGQAVSSPMVPGATAYWVPRVPSPIPPSGKQAMTSSEEDPDERSAGGDQGEYSEEYIYSAAEAGYQSPSVYAAAAESTTNLTIQEGSSRAGSPQEGVATYSYSQQVVVKSSVLSSSQPINSAPAAIFTSNSSSSSTGSSQTPPNSLQPNNILTPGQLPPGRPAVPWFVNELGEPVAMAPPPPYSYDPNGSDLPRDCKVLQYYYNLGVQWYQQSYWHSMVHLQQVYPHQAADAQFQSYQSTAPPADHTVPQAYPDSVRMCPHPQGDMPSNGAPLGMENPPTVVPGTVFYPVVQEQCGQPALHSTYDPYMPVLSTTYHYLTPWTPGAAPHSRFHHTTYCPSSSHPPVNYITAPGHPNHLPHSQFV
Protein: ATP-dependent DEAD/H RNA helicase, putative (Q384W4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ribosome biogenesis protein BOP1 homolog
- NLE domain-containing protein
- Pescadillo homolog
- ATP-dependent RNA helicase
- Ribosomal protein L1p/L10e family
- RNA-binding protein, putative
- Nucleolar GTP-binding protein 1
- Nucleolar complex protein 2
- Ribosome assembly factor mrt4
- rRNA processing protein, putative
Sequence:
MKTFGVRYLKYLKGSRAAYGGSAGSLLDDYMRQGGEAHAANLPPSQKFFYARDATRDSGASQRHRTVQLRLGSAQMLSPTTANIANNNEAHPLFFSQTAPRGAGLCISLVVALKKLGIGRLTELQGALIPLLLKGKHVIAHAETGTGKSFGIALACANRIIRENINYRLHTVIIVPTQELALQYDKWLRHFCGSTQQVVQVAIESITLEVQLAKLHNIQPHVLVGTPQRVADVLRFSPTLLGEKLRRKVDCVILDEADIVLFGNIRFGRQHISGINLVDRLFRSRREEVPAQIVAASATIDGRTAQALNMWMRNDKAVRLTTSFVEHTIPQTISFYFYSESRSYPLPRSLELILRLICKQEANPRVLLFTTQEEVGSVTNQLNTLKSTSPEVQKWLRWNGKREIAAPLETLLDPEKGKPKRICRSKGDVYVKDNSSIEKLNTGLLLVGVSSHSLSRGIHINEVTHVILFGECPPASVFVHCAGRTGRMGKEGHVVLLYPPQSGRTVQQVCEAVEVPFLPGRMEQVEELLLGGDFSSVDALREVSGAKCAY
Protein: FI05319p (I-kappaB kinase epsilon, isoform B) (I-kappaB kinase epsilon, isoform C) (Q9V3Y8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- RE66324p
- GH01161p
- Stimulator of interferon genes protein homolog
- Protein spindle-F
- LD20892p
- E3 ubiquitin-protein ligase lubel
- Signal transducer and transcription activator
- Death-associated inhibitor of apoptosis 1
- Dynein light chain 1, cytoplasmic
- ubiquitinyl hydrolase 1
Sequence:
MSFLRGSVSYVWCTTSVLGKGATGSVFQGVNKITGESVAVKTFNPYSHMRPADVQMREFEALKKVNHENIVKLLAIEEDQEGRGKVIVMELCTGGSLFNILDDPENSYGLPEHEFLLVLEHLCAGMKHLRDNKLVHRDLKPGNIMKFISEDGQTIYKLTDFGAARELEDNQPFASLYGTEEYLHPDLYERAVLRKSIQRSFTANVDLWSIGVTLYHVATGNLPFRPFGGRKNRETMHQITTKKASGVISGTQLSENGPIEWSTTLPPHAHLSQGLKTLVTPLLAGLLEENREKTWSFDRFFHEVTLILRKRVIHVFFTNRTSSVEVFLEPDEQIDNFRERIFLQTEVPLEKQILLFNNEHLEKKVTPRTIAKAFPATTTDQPIFLYSNDDNNVQLPQQLDLPKFPVFPPNVSVENDASLAKSACSVGHECKRRVDIFTSMDILIKKGVEHFIEMLVTTITLLLKKTESFDNLLSTVIDYADVVHSMARVTKGDQEIKTLLTALENVKSDFDGAADVISQMHKHFVIDDELNDQWTSSMHGKKCPCKTRASAQAKYLVERLRDSWQHLLRDRATRTLTYNDEQFHALEKIKVDHNGKRIKALLLDNVNPTVAQIAECLADWYKLAQTVYLKTQILEKDVRDCERKLNGIRDELYHVKSELKLDVDTKTINNNNQLAKIEERNRLRVMQQQQQEVMAVMRTNSDIISLLSKLGITNGSLESS
Protein: Uncharacterized RING finger membrane protein C15C4.06c (Q1MTR5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Vacuole membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MHLCNNQLLDHLDCNAVYRGYVSQENKVKRRKRLFNAIRKLWNERRRYRMPKDESISPTPISYSFRSLRRGHTSGHASEHTSSSRSSHDESDSMSSSSESDSDSVSSESNPKSYSDSSTSSARSSSTSGSISLYDDYYPAYSSNAPNTAISNYVSSGLSYYGNSSIIMNAVEYNQFFPLTITTLIVKNNKNVVSNLPKNVSFYFHSDNTVLLNEYYKSLSKLKNNFRGIIYKTTPYGSCNDTESLQVDTKGSVWFRDVSNMGSSGLIAFAPFDYCAPMHVLQAVQDRAKAILFYNASTASNSLTNFDHFEDAVDMITFETLPMALISYENGIAFEKILNEYSASSLNSVQDGGALVEYFGNIDATARLGVIISKEPKLLGLYIFIGVLLGLIGVIGLFICLHFSGAMNGFYRLLNRHGIPVQERIVNIGPNKPENRVTKEMLDTLPVRMFSGPHLANPNDELVYEKDWKLDKSESFDGQGNVVTTAERGSKYFDQRECTICLCEYSEESPLYRELPCHHIFHPACIDPYLLKNSDLCPLCKQSVTNMLENASEDNV
Protein: S-adenosylmethionine sensor upstream of mTORC1 (dSamtor) (Probable methyltransferase BMT2 homolog) (EC 2.1.1.-) (Q9W138)
Organism: Drosophila melanogaster (Fruit fly)
Function: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.
Interaction partners:
- GH04846p
- GATOR complex protein NPRL2
- Glycogen [starch] synthase
- GATOR complex protein Iml1
- GATOR complex protein NPRL3
Sequence:
MATEEHQRLASIVKSCHESLRQLTKEYGATAAWQEHTSPRNAKQLAEYAKAMKQLAAIWETNDGKVELQARSRIKWAIDYITKYFFTEGIYLQKRQREQRLLESYRAEGKLGEVQCRLMEEPPDRLHVLDVGSCFNPFSSAPHLEVTALDLCPATEDVLQADFLKVEVVPGIREPELEEGSVRRLPASHYECVIFSLLLEYMPSAEQRLQCCLQAYDLLLPEGILVLITPDSQHVGKNAHLMKNWRYSLARIGLLRVRFEKLPHISCMVFRKAISRELSQHWASIHREEGMCEEIRIPQDDS
Protein: FOS like 1, AP-1 transcription factor subunit (FOS-like antigen 1 isoform 2) (E9PPX2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKEGDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL
Protein: C-X-C chemokine receptor type 2 (High affinity interleukin-8 receptor B) (C9J2F9)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLA
Protein: Ethylene-responsive transcription factor ERF114 (ERF bud enhancer) (Q9FH54)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking, including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1, MARD1 and several genes encoding different types of cell wall-remodeling proteins.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Uncharacterized protein
- Phytosulfokines 5
- Phytosulfokines 2
- Putative small RNA degrading nuclease 4
- Amino acid transporter AVT1J
Sequence:
MYGKRPFGGDESEEREEDENLFPVFSARSQHDMRVMVSALTQVIGNQQSKSHDNISSIDDNYPSVYNPQDPNQQVAPTHQDQGDLRRRHYRGVRQRPWGKWAAEIRDPKKAARVWLGTFETAESAALAYDEAALKFKGSKAKLNFPERVQLGSNSTYYSSNQIPQMEPQSIPNYNQYYHDASSGDMLSFNLGGGYGSGTGYSMSHDNSTTTAATTSSSSGGSSRQQEEQDYARFWRFGDSSSSPHSGY
Protein: Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein) (Q5TKA1)
Organism: Homo sapiens (Human)
Function: Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:15538385, ECO:0000269|PubMed:16730350}. Note=Found in perinucleolar structures. Associated with chromatin.
Interaction partners:
- Histone-binding protein RBBP4
- Myb-related protein B
- Protein lin-37 homolog
- Protein lin-52 homolog
- Protein lin-54 homolog
- Transcription factor E2F4
- Retinoblastoma-like protein 2
- Myb-related protein A
- Retinoblastoma-like protein 1
- Histone-binding protein RBBP7
Sequence:
MAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNTSSAVEMPFRNSKRSRLFSDEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKASQKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVADVSQFKDLPDEIPLPLVIGTKVTARLRGVHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPSRFFMTPPRLHYTPPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLISRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQNNVEIHVAHIQSGLSQMGNLHAFAANNTNRD
Protein: Galacturonosyltransferase 8 (EC 2.4.1.-) (Glycosyltransferase QUASIMODO1) (Q9LSG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Alpha-1-4-D-galacturonosyltransferase involved in homogalacturonan (HGA) synthesis, a class of pectin which plays a role in cell adhesion.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Probable pectin methyltransferase QUA2
- Protein ESMERALDA 1
- Glycosylinositol phosphorylceramide mannosyl transferase 1
- Protein FRIABLE 1
- AT4g38500/F20M13_60
- Alkaline-phosphatase-like family protein
- Granule-bound starch synthase 1, chloroplastic/amyloplastic
- Galacturonosyltransferase
- Probable pectin methylesterase CGR3
- Xyloglucan 6-xylosyltransferase 2
Sequence:
MANHHRLLRGGGSPAIIGGRITLTAFASTIALFLFTLSFFFASDSNDSPDLLLPGVEYSNGVGSRRSMLDIKSDPLKPRLIQIRKQADDHRSLALAYASYARKLKLENSKLVRIFADLSRNYTDLINKPTYRALYDSDGASIEESVLRQFEKEVKERIKMTRQVIAEAKESFDNQLKIQKLKDTIFAVNEQLTNAKKQGAFSSLIAAKSIPKGLHCLAMRLMEERIAHPEKYTDEGKDRPRELEDPNLYHYAIFSDNVIAASVVVNSAVKNAKEPWKHVFHVVTDKMNLGAMQVMFKLKEYKGAHVEVKAVEDYTFLNSSYVPVLKQLESANLQKFYFENKLENATKDTTNMKFRNPKYLSILNHLRFYLPEMYPKLHRILFLDDDVVVQKDLTGLWEIDMDGKVNGAVETCFGSFHRYAQYMNFSHPLIKEKFNPKACAWAYGMNFFDLDAWRREKCTEEYHYWQNLNENRALWKLGTLPPGLITFYSTTKPLDKSWHVLGLGYNPSISMDEIRNAAVVHFNGNMKPWLDIAMNQFRPLWTKHVDYDLEFVQACNFGL