wanglab/gogpt-training-data huggingface dataset:
Protein: At4g24090 (Homer protein) (Q5XEV6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DNA repair metallo-beta-lactamase family protein
- Metallo-beta-lactamase family protein
Sequence:
MQSLSLQSLPWKPNSVTLPEINLLNPKQLTASSSQYRRTRNWRIRSSSEDNVAISSDGGDLKNSLSGIVGNQVEELLSREENKGLLDGLEKASLRVEIAKRELEDIERQEIEAKLLQDYINQLESRAAEIAECQQEIDAARSMVEEAERSLSLADNSTIGSSEKGYSIDKDKERLESAKAAVIAAAVGTIAELPFALSQVASMEQLVLPLGIAFASCALFGVTFRYAVRRDLDDNHLKSGAVAAFGFVKGLGMLSRGPPLELSWESLFSHGIDGAVLVSQSVLIFAFASIGLDFCFKMKLLRPFPSSD
Protein: Arm repeat protein (Q9NHP1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
Interaction partners:
Sequence:
MEARSLKHSLIGLNMNSTHINMDLSLTHEPANMQSQFGSFQNYDQFSAAGYSSTPLYITKPTGVGAITKVAPHCSQNKIETNSTDNSIPDIENHPLATTVRYVQAGQYEDTSEYGVAGLTCGIDSEYTAEAVVPYCYTSDANYTGIQNTTSSIKPFSGRPFNDNINGAEAVADSQCRTFKSSAEFKLPQFAMSSINTVPQRLEEKDDYIEGSENDICSTMRWRDPNLSEVISFLSNPSSAIKANAAAYLQHLCYMDDPNKQRTRSLGGIPPLVRLLSYDSPEIHKNACGALRNLSYGRQNDENKRGIKNAGGIAALVHLLCRSQETEVKELVTGVLWNMSSCEDLKRSIIDEALVAIVCSVIKPHSGWDAVCCGETCFSTVFRNASGVLRNVSSAGEHARGCLRNCEHLVECLLYVVRTSIEKNNIGNKTVENCVCILRNLSYRCQEVDDPNYDKHPFITPERVIPSSSKGENLGCFGTNKKKKEANNSDALNEYNISADYSKSSVTYNKLNKGYEQLWQPEVVQYYLSLLQSCSNPETLEAAAGAIQNLSACYWQPSIDIRATVRKEKGLPILVELLRMEVDRVVCAVATALRNLAIDQRNKELIGKYAMRDLVQKLPSGNVQHDQNTSDDTITAVLATINEVIKKNPEFSRSLLDSGGIDRLMNITKRKEKYTSCVLKFASQVLYTMWQHNELRDVYKKNGWKEQDFVSKHFTAHNTPPSSPNNVNNTLNRPMASQGRTRYEDRTIQRGTSTLYSANDSSGAVMSNESAMLSEMVRKQL
Protein: Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (Q6GN86)
Organism: Xenopus laevis (African clawed frog)
Function: May play a dynamic role in flagellar motility.
Subcellular location: Cell projection, cilium {ECO:0000250|UniProtKB:O14645}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:O14645}. Dynein axonemal particle {ECO:0000269|PubMed:33263282}. Cytoplasm {ECO:0000250|UniProtKB:Q8BVN8}.
Interaction partners:
- WD_REPEATS_REGION domain-containing protein.
- GAS domain-containing protein.
- Zinc finger MYND domain-containing protein 10
- Coiled-coil domain-containing protein 39
- Dynein axonemal intermediate chain 1
- Uncharacterized protein.
- Dynein heavy chain 5, axonemal isoform X2
- Uncharacterized protein.
- Dynein axonemal assembly factor 3
- Radial spoke head protein 9 homolog
Sequence:
MIPPADSLLKHDNPVLISKNTERKSPKSRPLKVSSPQTVLTAPVPPPPKPKTPLLDATKPAEEILNAILPPREWVENNQLWIQQVSSTPSTRMDVVHLQEELDMKLQQRQARETGICPVRRELYSQCFDELIRQVTINCAERGLLLLRVRDEIHMTISAYQTLYESSVAFGMRKALQAEQGKSDMEKRMADLEMEKKDLERQVNEQKAKCEAIEKREAERRQVEEKKHAEEIQFLKRTNQQLKAQLEGIIAPKK
Protein: Small ribosomal subunit protein mS35 (37S ribosomal protein S24, mitochondrial) (Q09705)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in mitochondrial genome encoded proteins translation.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q03976}.
Interaction partners:
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein uS4m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS2m
Sequence:
MAFNPLLSLLKADAIFLGQLSKSSFCATSRAFSVFYFTRFKRSAYVSAPFGIEPHDEKELKTIDDNVHSNNLSWQKIQEHEVIRELYRKAAYELPGLTPYTQSFKKPADSQIFRFESDVQMSSFEKMNPKVVVTFKVTNIPLLEEKQRHVLRLLVGPRYNPEEDLVRISSDKYSSALQNKYHLIKILTSLIEESKRNAEKFSHVPLNTGHWKYKKCDKRMPQEWLADATTLTSKKKTTIGKQSHNTVLERESIATTDE
Protein: GH11193p (Rab18) (Q9W4A0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RINT1-like protein
- Centromere/kinetochore protein zw10
- Rab3 GTPase-activating protein catalytic subunit
- Syntaxin-18
- Rab GDP dissociation inhibitor
- Rab3 GTPase-activating protein non-catalytic subunit
- Rab proteins geranylgeranyltransferase component A
- RE60063p
- Ras-related protein Rab-43
- Seipin
Sequence:
MADRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKIDEERVVDREEGRKFARKHRALFIETSAKCDQFVSDVFKDVVEKIVSSEYFNNGNASAGLDIASDRDLEASASTCYC
Protein: Inhibitory synaptic factor 1 (InSyn1) (Q8CD60)
Organism: Mus musculus (Mouse)
Function: Component of the protein machinery at the inhibitory synapses, probably acting as a scaffold. Inhibitory synapses dampen neuronal activity through postsynaptic hyperpolarization. This synaptic inhibition is fundamental for the functioning of the central nervous system, shaping and orchestrating the flow of information through neuronal networks to generate a precise neural code.
Subcellular location: Postsynaptic density {ECO:0000269|PubMed:27609886}.
Interaction partners:
- IQ motif and SEC7 domain-containing protein 3
- Gephyrin
Sequence:
MNIRGAPDLGQPSDDPNSGGERERIRQRMKMVIGQLEGILRELKEVAKELREVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGVGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPSDSVDGPEAPRPGTGPDYQLMNGGLPIPNGPRVETPDSSSEEAFSAGPAKGQVPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEEGEEEEEGDLAPELPRVEPHTGPLKPSPAPYKTKRSPLTTRRLGPTLAPEQTRRVTRNSSTQTVSDKSTQTVLPYTATKQKAKGKN
Protein: Kinesin-like protein at 67A, isoform B (EC 5.6.1.3) (M9PF35)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MPSEQHTNIKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYRDITKRMNKKLTMEFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHPGLTYLTMQDLFDKIQAQSDVRKFDVGVSYLEVYNEHVMNLLTKSGPLKLREDNNGVVVSGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERKTDTKRTVKLSMIDLAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLADGLKHIPYRDSNLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENERLKERNKALEAKATQLERAGNSGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRSKIKNINYRQTLKKELEEFRKLMCVDQRVCQEDFRRFANYMSTLTSQMEKYKEELPSWLSKMEIAYQDLESLKREVNKSKAYQILIVYVKYKDLELQLTKQNIFNNHVNAINQELVENLDLMRKSFRTACEVLNQTYDRLEDGQKLTPEIEAVFERLLRKMRFADSEANTKMAEMNPLAVPVALRSSAQEEEEPTCSLTASAKKRQRQAAQSDDDLHLSMEDFDSQDTESDSEELHRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSARKALTATVTKPRTVQQRLVSDLISDQNVRGGNEKIKKAKFFC
Protein: Adenosine deaminase RL5 (EC 3.5.4.4) (Laccase RL5) (Multicopper oxidase RL5) (Polyphenol oxidase) (EC 1.10.3.-) (Purine nucleoside phosphorylase RL5) (EC 2.4.2.1) (S-methyl-5'-thioadenosine phosphorylase RL5) (EC 2.4.2.28) (Q1EIR0)
Organism: Unknown prokaryotic organism
Function: Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine (By similarity). Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate (By similarity). Also has adenosine deaminase activity (By similarity). Also acts as a multicopper oxidase able to oxidize a wide variety of polyphenols and related compounds in vitro. Displays substrate preference as follows: syringaldazine > 2,6-dimethoxyphenol > veratryl alcohol > guaiacol > tetramethylbenzidine > 4-methoxybenzyl alcohol > 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) >> phenol red > 1-hydroxybenzotriazole. Cannot use 3,4-dimetoxybenzyl alcohol and violuric acid as substrates. As this enzyme is derived from a rumen microbial community, it may have a role in the digestion of complex plant materials such as ryegrass lignin.
Interaction partners:
Sequence:
MIELEKLDFAKSVEGVEAFSTTRGQVDGRNAYSGVNLCDYVGDDALRVLDARLTLAMQLGVDLDDLVMPRQTHSCRVAVIDERFRALDIDEQEAALEGVDALVTRLQGIVIGVNTADCVPIVLVDSQAGIVAVSHAGWRGTVGRIAKAVVEEMCRQGATVDRIQAAMGPSICQDCFEVGDEVVEAFKKAHFNLNDIVVRNPATGKAHIDLRAANRAVLVAAGVPAANIVESQHCSRCEHTSFFSARRLGINSGRTFTGIYRK
Protein: Eyes absent homolog (EC 3.1.3.48) (A0A2R8Y6K4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEDPRGINGQSVQTSQASSDVAVSSSCRSMEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL
Protein: Ras-related protein Rab-3D (EC 3.6.5.2) (O95716)
Organism: Homo sapiens (Human)
Function: Protein transport. Probably involved in regulated exocytosis (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Alpha-2-macroglobulin receptor-associated protein
- Geranylgeranyl transferase type-2 subunit alpha
Sequence:
MASAGDTQAGPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSSSSGSNGKGPAVGDAPAPQPSSCSC
Protein: Probable splicing factor, arginine/serine-rich 5 (CeSC35-2) (RNA-binding protein srp-3) (Q10021)
Organism: Caenorhabditis elegans
Function: Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaphrodites.
Subcellular location: Nucleus {ECO:0000269|PubMed:10906451}.
Interaction partners:
- Probable splicing factor, arginine/serine-rich 7
- Probable splicing factor, arginine/serine-rich 6
- Probable splicing factor, arginine/serine-rich 4
- RRM domain-containing protein
- Splicing factor U2AF 65 kDa subunit
- Splicing factor U2AF 35 kDa subunit
- RRM domain-containing protein
- Pre-mRNA-splicing factor SLU7
- Pre-mRNA-processing factor 17
- Probable splicing factor, arginine/serine-rich 2
Sequence:
MPRLYLGKIPYNARERDVERFLKGYGKINNISMKYGFAFVDFEDSRDAEDACHDLDGKTMEGSSMRLVVEMARGKPRGNDRHGSRSPRRRSRSPRRRSRTPPRRRSRSRDRKRSRRSRSRSSSRSRSPVRESRRRSESRSPSPKRDLKREASRSRSPLPAKDRSRTRSGSPPKNGGDRKRSVSRGRSHSRDGSNRSVSRSPSPGSPKD
Protein: Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)] (P97467)
Organism: Mus musculus (Mouse)
Function: Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive alpha-amidated peptides, a terminal modification in biosynthesis of many neural and endocrine peptides (By similarity). Alpha-amidation involves two sequential reactions, both of which are catalyzed by separate catalytic domains of the enzyme. The first step, catalyzed by peptidyl alpha-hydroxylating monooxygenase (PHM) domain, is the copper-, ascorbate-, and O2- dependent stereospecific hydroxylation (with S stereochemistry) at the alpha-carbon (C-alpha) of the C-terminal glycine of the peptidylglycine substrate (By similarity). The second step, catalyzed by the peptidylglycine amidoglycolate lyase (PAL) domain, is the zinc-dependent cleavage of the N-C-alpha bond, producing the alpha-amidated peptide and glyoxylate (By similarity). Similarly, catalyzes the two-step conversion of an N-fatty acylglycine to a primary fatty acid amide and glyoxylate (Probable).
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:P10731}; Single-pass membrane protein {ECO:0000250|UniProtKB:P10731}. Note=Secretory granules. {ECO:0000250|UniProtKB:P10731}.
Interaction partners:
- Kalirin
Sequence:
MAGRARSRLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFSNECLGTTRPITPIDSSDFTLDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSLHLTRVPQPLIAGMYLMMSVNTVIPPGEKVVNSDISCHYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVAFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPEEANIPIPVKSDMVMIHGHHKETENKEKSALIQQPKQGEEEAFEQGDFYSLLSKLLGEREDVVHVHKYNPTEKTESGSDLVAEIANVVQKKDLGRSDAREGAEHEEGGNAILVRDRIHKFHRLESTLRPAESRALSFQQPGEGPWEPELAGDFHVEEALEWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNKAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLEPRSKEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVPHLNQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTESRLEVEHRSVKKAGIEVPEIKEAEAVVEPKVKNKPTSSELQKMQEKKKLIKDPGSGVPVVLITTLLVIPVVVLLAIAMFIRWKKSRAFGDHDRKLESSSGRVLGRLRGKGSSGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGSESEEEYSAPLPTPAPSS
Protein: Signal transducer and activator of transcription (A0A0G2K2M3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU046415}.
Interaction partners:
Sequence:
MSLWSLVSKMSPEKLQRLYVDFPQHLRHLLAEWLENQPWEFLVGSDAFCYNMASALLSATVQRLQASAGEQGKGSSLLQHISTLESIYQRDPLKLVATIRQILQGEKKAVIEEFHHLPGPFHRKQEELKFTTALGRLQHRVRETRILRESLQQGTKTAQVSLKNLIDPPANGTGPSEDLATMLQGTVGDLEATQALVLKRIQIWKRQQQLAGNGTPFEESLAGLQERTVFPDNCPGPRCESLVEIYSQLQQEIGAASGELEPKTRASLISRLDEVLRTLVTSSFLVEKQPPQVLKTQTKFQAGVRFLLGLQFLGTSAKPPLVRADMVTEKQARELSLPQGSGAGVESTGEIMNNTVPLENSVPGNCCSALFKNLLLKKIKRCERKGTESVTEEKCAVLFSTSFMLGPNKHLIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTSRGLLPEHFLFLAQKIFNDNSLSIEAFQHRCVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSSQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVSTTIKMTVERDQPLPTPEPQMPAMVAPYDLGMAPDASMQLSSDMVYPPQSHSIHSFQSIPLEESMSVLPPFQEPHLQMPPTMSQISMPFDQPHPQGLLQCQSQEHAVSSPEPLLCSDVTMAEDSCLTQPVQGFPQGTWVSEGMYPPLMPPTEQDLTKLLLEGQGEGGGSIGTQPLLQPSSYGQSGISMSHLDLRTNPSW
Protein: Growth/differentiation factor 8 (GDF-8) (Myostatin) (Q06BS3)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU369049}.
Interaction partners:
Sequence:
MQKLAVYVYIYLFMQIAVDPVALDGSSQPTENAEKDGLCNACTWRQNTKSSRIEAIKIQILSKLRLEQAPNISRDVIKQLLPKAPPLQELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLVQMEGKPKCCFFKFSSKIQYNKVVKAQLWIYLRQVQKPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKAFDETGRDLAVTFPGPGEDGLNPFLEVRVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
Protein: Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) (Q9BXB4)
Organism: Homo sapiens (Human)
Function: Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage. Weakly binds 25-hydroxycholesterol.
Subcellular location: Late endosome membrane {ECO:0000269|PubMed:20599956}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:20599956}. Note=Localizes at the Golgi-late endosome interface.
Interaction partners:
- Oxysterol-binding protein-related protein 9
- Oxysterol-binding protein-related protein 10
- Vesicle-associated membrane protein-associated protein B/C
- Vesicle-associated membrane protein-associated protein A
Sequence:
MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE
Protein: Ig lambda-1 chain C region (P01843)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
QPKSSPSVTLFPPSSEELETNKATLVCTITDFYPGVVTVDWKVDGTPVTQGMETTQPSKQSNNKYMASSYLTLTARAWERHSSYSCQVTHEGHTVEKSLSRADCS
Protein: Protein mac-1 (Member of AAA family that binds ced-4) (Q9NAG4)
Organism: Caenorhabditis elegans
Function: Probably together with ced-9, plays a modest role in preventing ced-4 and caspase ced-3-mediated apoptosis.
Interaction partners:
- mRNA transport homolog 4
- RRM domain-containing protein
- MI domain-containing protein
- Nucleolar complex protein 3 homolog
- RNA helicase
- Ribosome biogenesis protein BOP1 homolog
- Nucleolar GTP-binding protein 2
- WD repeat-containing protein 74
- Guanine nucleotide-binding protein-like 3 homolog
- Ribosome biogenesis protein WDR12 homolog
Sequence:
MPGGMGFPSDPALLPRVQAHIRKFPGTKYFKPELVAYDLQQEHPEYQRKNHKVFMGMVREALERIQLVAKEENDEKMEEKEAMDDVQEIPIVKALETRKRKAPAAGRKSTGQAAAAKEVVLSDDSEDERAARQLEKQIESLKTNRANKTVLNLYTKKSAPSTPVSTPKNQATKKPPGASAAPPALPRGLGAVSDTISPRESHVKFEHIGGADRQFLEVCRLAMHLKRPKTFATLGVDPPRGFIVHGPPGCGKTMFAQAVAGELAIPMLQLAATELVSGVSGETEEKIRRLFDTAKQNSPCILILDDIDAIAPRRETAQREMERRVVSQLCSSLDELVLPPREKPLKDQLTFGDDGSVAIIGDSPTAAGAGVLVIGTTSRPDAVDGGLRRAGRFENEISLGIPDETAREKILEKICKVNLAGDVTLKQIAKLTPGYVGADLQALIREAAKVAIDRVFDTIVVKNEGHKNLTVEQIKEELDRVLAWLQGDDDPSALSELNGGLQISFEDFERALSTIQPAAKREGFATVPDVSWDDIGALVEVRKQLEWSILYPIKRADDFAALGIDCRPQGILLCGPPGCGKTLLAKAVANETGMNFISVKGPELLNMYVGESERAVRTVFQRARDSQPCVIFFDEIDALVPKRSHGESSGGARLVNQLLTEMDGVEGRQKVFLIGATNRPDIVDAAILRPGRLDKILFVDFPSVEDRVDILRKSTKNGTRPMLGEDIDFHEIAQLPELAGFTGADLAALIHESSLLALQARVLENDESVKGVGMRHFREAASRIRPSVTEADRKKYEHMKKIYGLKQATPPSV
Protein: Uncharacterized protein YBL029W (P38201)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Uncharacterized protein YIL014C-A
- Uncharacterized membrane protein YOR034C-A
- Uncharacterized protein YGR161W-C
- DSC E3 ubiquitin ligase complex subunit 3
Sequence:
MCANIPEFDSFYENENINYNLESFAPLNCDVNSPFLPINNNDINVNAYGDENLTYSNFLLSYNDKLATTTAKNNSINNSNSNNNSNNNKNNNNNHNNNNLLGNDISQMAFLLDYPSTLNEPQFAVNCKDIYRKDISTPSSLVSSLPPAKFSLSLSNSPSPPPPSSSSLKHGEAIISNTSESSDIFADPNSFEKDTMPLTQELTLENLNNQLNYPDFTINAIEQDPAPSSFSSSSSSSESTVSSSRKRKPCHDSYTHSSPSSSESKKISDSRLSAEGLAKVLNLESPEEALKRERFILGIFQNELNYPLGYKTWIRDTTKEYRTKLINQLHERVKVKYPEYNQSILETIIRRGTYYMMQSRLRRERRMKLKERKRTT
Protein: Type 3 secretion system regulator YopR (T3SS regulator YopR) (Yersinia outer protein R) (Yersinia secretion protein H) (P68590)
Organism: Yersinia pestis
Function: Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function.
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q01249}. Note=Secreted via the type III secretion system (T3SS). {ECO:0000250|UniProtKB:Q01249}.
Interaction partners:
Sequence:
MTVTLNRGSITSLMSSSQAVSTLQPVASELKTQLENKLKSESAEKTREVLWQQYYASNPPDHAVLEVLATPVREALLARFGQHQGSVVPAIDLPELRSVLQQFDSFGKRWEAILLQVLEGIKPNESQVGLPYLSELINKELMILLPSNSIVDSLLHNSHQIDMDT
Protein: Metallothionein-like protein 1A (MT-1A) (MT-2) (MT-Q) (Protein LIGHT STRESS-REGULATED 4) (P43392)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable). Functions as metal chelator of copper (Cu) and zinc (Zn). Plays a role in Cu homeostasis in the roots under elevated Cu concentration. Functions cooperatively with the phytochelatin synthase PCS1 to protect plants from Cu and cadmium (Cd) toxicity. Plays a role in Cu homeostasis, specifically in the remobilization of Cu from senescing leaves. The mobilization of Cu from internal sources is important for seed development. Confers tolerance to Cd and plays a role in Cd and Zn homeostasis.
Interaction partners:
- Metallothionein-like protein 2B
- Metallothionein-like protein 2A
- Metallothionein-like protein 4A
- Metallothionein-like protein 4B
- Metal transporter Nramp5
- SelT-like protein
- Glutathione gamma-glutamylcysteinyltransferase 1
- Heavy metal-associated isoprenylated plant protein 24
- At2g28660
- Heavy metal-associated isoprenylated plant protein 23
Sequence:
MADSNCGCGSSCKCGDSCSCEKNYNKECDNCSCGSNCSCGSNCNC
Protein: Nuclear hormone receptor family member nhr-14 (O02151)
Organism: Caenorhabditis elegans
Function: Orphan nuclear receptor. Transcriptional repressor of intestinal metal transporter smf-3 and genes of the innate immune response. Inhibits nuclear localization of transcription factor pqm-1; in response to pathogen stress, may facilitate translocation of pqm-1, leading to transcriptional activation of genes involved in innate immunity and iron uptake.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
Sequence:
MDFLISTSLSESTSTSADFCVVCGDKAIGKHYGAVACNGCKGFFRRSVWQNLQYTCRFNKQCNIDKDHRNACRYCRFQKCLADGMKPEAIQNERDRIGSTKRRKRSGANSENNSDSEGTPSPKIEVMGNSVSRKLIEMLLDIEHRLASNQSMNALLRDESEMKNSRQRAVNYLIGWTNMLHPLPEVPLADKVLLLKKFSSAFTLLGTLQRSMALPHFVLPNDQVLSISASHPPELFEALTRIIDELLTPLRRLRTDHAEFSCLKALLLLNPDVVGISNNTRERIREARDALLKTLFAYMSNTQNSIDASLRVSSLLMIIPSLISVSSSIMEFPALSDLFGLGDVIKRDTISPKIETPPLEMKPMMPKIAQPPVTSAPTVPTNIMMNKDLISQIMNNPQLFPLLPMPQTASPPMSFMGQSEFGCHLQSMPVKVILS
Protein: Protein HP_1247 (O25842)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Could be the functional equivalent of DNA polymerase III delta subunit (HolA).
Interaction partners:
- DNA polymerase III delta prime subunit
- Beta sliding clamp
- DNA polymerase III subunit alpha
- DNA polymerase III subunit gamma/tau
- DNA polymerase III epsilon subunit
- Ribonuclease R
- Shikimate dehydrogenase
- Tryptophan--tRNA ligase
- SH3b domain-containing protein
- Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein
Sequence:
MYRKDLDHYLKQRLPKAVFLYGEFDFFIHYYIQTISALFKCDNPDIETSLFYASDYEKSQIATLLEQDSLFGGSSLVVLKLDFALHKKFKENDINLFLKALERPSHNRLIIGLYNAKSDTTKYKYTSDAIVKFFQKSPLKDEAICARFFIPKTWESLKFLQERANFLHLDISGHLLNALFEINNEDLGVSFNDLDKLAVLNAPITLEDIQELSSNAGDMDLQKLILGLFLKKSALDIYDYLLKEGKKDADILRGLERYFYQLFLFFAHIKTTGLMDAKEVLGYAPPKEIAENYAKNALRLKEAGYKRVFEIFRLWHIQSMQGQKELGFLYLTSIQKIINP
Protein: Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2) (Q90592)
Organism: Gallus gallus (Chicken)
Function: Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P11168}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Phosphotransferase.
- Solute carrier family 15 member 1
- Insulin
- Glucose-6-phosphatase
- Amino acid transporter
- Amino acid transporter
- Amino acid transporter.
- Amino acid transporter.
- Glucose-6-phosphatase
- Pro-glucagon
Sequence:
MDGKSKMQAEKHLTGTLVLSVFTAVLGFFQYGYSLGVINAPQKVIEAHYGRMLGAIPMVRHATNTSRDNATITVTIPGTEAWGSSEGTLAPSAGFEDPTVSPHILTMYWSLSVSMFAVGGMVSSFTVGWIGDRLGRVKAMLVVNVLSIAGNLLMGLAKMGPSHILIIAGRAITGLYCGLSSGLVPMYVSEVSPTALRGALGTLHQLAIVTGILISQVLGLDFLLGNDELWPLLLGLSGVAALLQFFLLLLCPESPRYLYIKLGKVEEAKKSLKRLRGNCDPMKEIAEMEKEKQEAASEKRVSIGQLFSSSKYRQAVIVALMVQISQQFSGINAIFYYSTNIFQRAGVGQPVYATIGVGVVNTVFTVISVFLVEKAGRRSLFLAGLMGMLISAVAMTVGLVLLSQFAWMSYVSMVAIFLFVIFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFCNWACNFIVGMCFQYIADLCGPYVFVVFAVLLLVFFLFAYLKVPETKGKSFEEIAAAFRRKKLPAKSMTELEDLRGGEEA
Protein: BHLH transcription factor (Os08g0483900 protein) (cDNA clone:002-131-D10, full insert sequence) (Q6YTU1)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MALEAVVFSEGYYFGCGGAMAAEAAAGGAWSWSHGYGGGVDQGKGAMELVVDDGVVNAFWDGGGGGASSSPVMAAVSGFIEEPDGGNSSVADAAPPPEHGGASVVGRDGSAAAPAAAAGRRKRRRARTVKNREEVESQRMTHIAVERNRRKQMNEYLAVLRSLMPASYVQRGDQASIIGGAINYVKEMEQLLQSLEAHRHARRARTDAAAALPFAGFFTFPQYSMSAVPTTTTTTVAAAATENGNAVAGAGAGDDADADVSGSKPSSVADIEVTMVESHANLKVLSRRRPRQLLRMVAGLQHHRLAVLHLNVASAGHMALYSLSLKVEEDCQLTSVDDIAAAVHGIVETIEQEQQQQQKQSCS