wanglab/gogpt-training-data huggingface dataset:
Protein: C-X-C motif chemokine 13 (B lymphocyte chemoattractant) (CXC chemokine BLC) (Small-inducible cytokine B13) (O55038)
Organism: Mus musculus (Mouse)
Function: Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.
Subcellular location: Secreted.
Interaction partners:
- C-X-C chemokine receptor type 5
- C-X-C chemokine receptor type 2
- C-X-C chemokine receptor type 4
- C-C chemokine receptor type 7
- C-X-C chemokine receptor type 3
- C-X-C motif chemokine 9
- C-X-C motif chemokine 10
- C-X-C chemokine receptor type 1
- C-C motif chemokine 19
- Platelet factor 4
Sequence:
MRLSTATLLLLLASCLSPGHGILEAHYTNLKCRCSGVISTVVGLNIIDRIQVTPPGNGCPKTEVVIWTKMKKVICVNPRAKWLQRLLRHVQSKSLSSTPQAPVSKRRAA
Protein: Pollen receptor-like kinase 1 (AtPRK1) (EC 2.7.11.1) (LRR receptor-like serine/threonine-protein kinase RLK) (C0LGU0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth.
Subcellular location: Cell membrane {ECO:0000269|PubMed:18591430}; Single-pass type I membrane protein {ECO:0000269|PubMed:18591430}. Note=Preferentially localized to the apical region of the pollen tube plasma membrane.
Interaction partners:
- Protein LURE 1.2
- Rac-like GTP-binding protein ARAC11
- Cystatin/monellin superfamily protein
- Rop guanine nucleotide exchange factor 12
- F-box/LRR-repeat protein At3g59250
- Protein NETWORKED 1B
- Protein NETWORKED 2A
- Protein LURE 1.1
Sequence:
MPPMQARTLSVYNVMVPLVCLLLFFSTPTHGLSDSEAILKFKESLVVGQENALASWNAKSPPCTWSGVLCNGGSVWRLQMENLELSGSIDIEALSGLTSLRTLSFMNNKFEGPFPDFKKLAALKSLYLSNNQFGGDIPGDAFEGMGWLKKVHLAQNKFTGQIPSSVAKLPKLLELRLDGNQFTGEIPEFEHQLHLLNLSNNALTGPIPESLSMTDPKVFEGNKGLYGKPLETECDSPYIEHPPQSEARPKSSSRGPLVITAIVAALTILIILGVIFLLNRSYKNKKPRLAVETGPSSLQKKTGIREADQSRRDRKKADHRKGSGTTKRMGAAAGVENTKLSFLREDREKFDLQDLLKASAEILGSGCFGASYKAVLSSGQMMVVKRFKQMNNAGRDEFQEHMKRLGRLMHHNLLSIVAYYYRKEEKLLVCDFAERGSLAINLHSNQSLGKPSLDWPTRLKIVKGVAKGLFYLHQDLPSLMAPHGHLKSSNVLLTKTFEPLLTDYGLIPLINQEKAQMHMAAYRSPEYLQHRRITKKTDVWGLGILILEILTGKFPANFSQSSEEDLASWVNSGFHGVWAPSLFDKGMGKTSHCEGQILKLLTIGLNCCEPDVEKRLDIGQAVEKIEELKEREGDDDDFYSTYVSETDGRSSKGESCESISFA
Protein: Sideroflexin-5 (Tricarboxylate carrier BBG-TCC) (Q8CFD0)
Organism: Rattus norvegicus (Rat)
Function: Mitochondrial amino-acid transporter (By similarity). Transports citrate. Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). In brown adipose tissue, plays a role in the regulation of UCP1-dependent thermogenesis probably by supporting mitochondrial glycerol-3-phosphate utilization (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:12150972}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MADTATTASAASAAASASNASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIARATSSRTVVYNKGL
Protein: Putative cadmium/zinc-transporting ATPase HMA4 (EC 7.2.2.12) (EC 7.2.2.21) (Protein HEAVY METAL ATPASE 4) (Putative cadmium/zinc-transporting ATPase 2) (O64474)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in cadmium/zinc transport.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Copper chaperone for superoxide dismutase, chloroplastic/cytosolic
- Metal tolerance protein 1
- Metal transporter Nramp3
- Metal transporter Nramp1
- Vacuolar cation/proton exchanger 4
- Protein PLANT CADMIUM RESISTANCE 2
- Metal tolerance protein A2
- Nicotianamine synthase 2
- Metal transporter Nramp4
- Metal transporter Nramp5
Sequence:
MALQNKEEEKKKVKKLQKSYFDVLGICCTSEVPIIENILKSLDGVKEYSVIVPSRTVIVVHDSLLISPFQIAKALNEARLEANVRVNGETSFKNKWPSPFAVVSGLLLLLSFLKFVYSPLRWLAVAAVAAGIYPILAKAFASIKRPRIDINILVIITVIATLAMQDFMEAAAVVFLFTISDWLETRASYKATSVMQSLMSLAPQKAIIAETGEEVEVDEVKVDTVVAVKAGETIPIDGIVVDGNCEVDEKTLTGEAFPVPKQRDSTVWAGTINLNGYICVKTTSLAGDCVVAKMAKLVEEAQSSKTKSQRLIDKCSQYYTPAIILVSACVAIVPVIMKVHNLKHWFHLALVVLVSGCPCGLILSTPVATFCALTKAATSGLLIKSADYLDTLSKIKIVAFDKTGTITRGEFIVIDFKSLSRDINLRSLLYWVSSVESKSSHPMAATIVDYAKSVSVEPRPEEVEDYQNFPGEGIYGKIDGNDIFIGNKKIASRAGCSTVPEIEVDTKGGKTVGYVYVGERLAGFFNLSDACRSGVSQAMAELKSLGIKTAMLTGDNQAAAMHAQEQLGNVLDVVHGDLLPEDKSRIIQEFKKEGPTAMVGDGVNDAPALATADIGISMGISGSALATQTGNIILMSNDIRRIPQAVKLARRARRKVVENVCLSIILKAGILALAFAGHPLIWAAVLVDVGTCLLVIFNSMLLLREKKKIGNKKCYRASTSKLNGRKLEGDDDYVVDLEAGLLTKSGNGQCKSSCCGDKKNQENVVMMKPSSKTSSDHSHPGCCGDKKEEKVKPLVKDGCCSEKTRKSEGDMVSLSSCKKSSHVKHDLKMKGGSGCCASKNEKGKEVVAKSCCEKPKQQVESVGDCKSGHCEKKKQAEDIVVPVQIIGHALTHVEIELQTKETCKTSCCDSKEKVKETGLLLSSENTPYLEKGVLIKDEGNCKSGSENMGTVKQSCHEKGCSDEKQTGEITLASEEETDDQDCSSGCCVNEGTVKQSFDEKKHSVLVEKEGLDMETGFCCDAKLVCCGNTEGEVKEQCRLEIKKEEHCKSGCCGEEIQTGEITLVSEEETESTNCSTGCCVDKEEVTQTCHEKPASLVVSGLEVKKDEHCESSHRAVKVETCCKVKIPEACASKCRDRAKRHSGKSCCRSYAKELCSHRHHHHHHHHHHHVSA
Protein: Rap1GAP (Q86RS9)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
DWIYSWKDSIFYGMCSCSGSPSYHEKDVPHPHDRLDMPLQLKAYRRNSLNAEGYYRDLERMHERGLFTTGINYNAEKSEDFLNMIERMQSNRLDDQRCEMPERTHNPTSGHQNEQTHQKTNGSAVHNQLTRNIMNEVLTKVGPYPQIVLPSNGFWMDGVNQQHHMDDQVNNMNVNSCARFKLETDETSHCYRRHFFGREHHDFFANDPIVGPLVLSVRTEVISSCDHFRIILRTRKGTIHEIVSATGLADRPSASRMAKLLCEEITTEQFSPVAFPGGSELIVQYDEHVLTNTYKFGVIYQKGGQTTEEQLFGNPHGSPAFDEFLSMIGDSVQLNGFQKYRGGLDTAHNQTGHQSVFSEFKNREIMFHVSTMLPYTIGDAQQLQRKRHIGNDIVAIIFQEANTPFAPDMIASNFLHAYVVVQPIDALTDRVRYRVSVAARDDVPFFGPTLPTPSIFKRGQDFRNFLLTKLINAENAAYKSSKFAKLAERTRSSLLDGLHATLRERAEFYATPLLESTSSGGESAATTSSSSNSYGGGILSSVKKAFIGRSRSVSQEASHVPHRAATINVTSRPKKSISSTSSSTSARTHSPIRDEEVVKPYRKEWEISSQESPDNEHDSDTGMESMSSTEMSGQTRASSCTFCVDDFHVAANHQSSDAKRLETLCVDVTRLQNEKHDLLRQNVSCKTDIKKLKDRQSVLSEELERANDEISRLRRMLKKPSNSDMAPVHQHFERSYSDVSV
Protein: Sll1939 protein (P73081)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- UvrABC system protein B
- Sll0169 protein
- Transcription-repair-coupling factor
- Sll1516 protein
- Slr0211 protein
- Slr0287 protein
- DNA 3'-5' helicase
- Sll0072 protein
- Sll1940 protein
- Slr1546 protein
Sequence:
MTISQAQKDPGILQTVSLLTAYCFDLRGMAPKQVINGWLKNFSALWIRLAVIEALYLGRYKAVSVEHLLEFWHKKGQPNFHFSAEFERLVSENLPRSLAIARDESMEELTKMADQSWQLKVPTAGQEQSLQSPRRRVSPSDPGELEPLPWHHRALGNIQHPNQENLKGSNVSEEGPVTRNPGPAPSIEQFIPITQESNFLSRLQSVLSQDTENV
Protein: Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein) (Q3U7R1)
Organism: Mus musculus (Mouse)
Function: Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9BSJ8}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q9BSJ8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9BSJ8}. Note=Localizes primarily to the endoplasmic reticulum. Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. {ECO:0000250|UniProtKB:Q9BSJ8}.
Interaction partners:
- Extended synaptotagmin-2
- Extended synaptotagmin-3
Sequence:
MEHSPEEGASPEPSGQPPATDSTRDGGSGVPPAGPGAASEALAVLTSFGRRLLVLVPVYLAGAAGLSVGFVLFGLALYLGWRRVRDGKERSLRAARQLLDDEERITAETLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGANPHLQTFTFTRVELGEKPLRIIGVKVHPSQRKDQILLDLNVSYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLTGDLPIVGAVSMFFIKRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDNWYPLQGGQGQVHLRLEWLSLLPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTASELTLDQWFQLSSSGPNSRLYMKLVMRILYLDYSEIRFPTVPGAQDWDRESLETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDKDLDKDDFLGRYKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVFLERAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQVRGEGTGTLGSVSLPLSELLQEDQLCLDHWFALSGQGQVLMRAQLGILVSQHSGVEAHSHSYSHSHSSSSLNDEPEALGGPTHPASPVLEVRHRLTHGDSPSEAPVGPLGQVKLTVWYHSDEQKLISIIHSCRALRQNGRDLPDPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEWDLPLDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLSQGAAQWYDLMDDRDKGGS
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Q8I6S4)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- U4/U6 small nuclear ribonucleoprotein PRP3, putative
- U4/U6 small nuclear ribonucleoprotein PRP31, putative
- Ran-specific GTPase-activating protein 1, putative
- Uncharacterized protein
- H/ACA ribonucleoprotein complex subunit 2
- U4/U6 small nuclear ribonucleoprotein PRP4, putative
- U6 snRNA-associated Sm-like protein LSm4
- Zinc finger protein, putative
- Sm protein F
- U5 small nuclear ribonucleoprotein component, putative
Sequence:
MKNLNQNMKNNDNKKNEKISGLEENEEHNNNNIVPYYLSNLLTNPSNPVVFMDINLGNHFLGKFKFELFQNIVPRTSENFRKFCTGEHKINNLPVGYKNTTFHRVIKDFMIQGGDFVNYNGSGCISIYGEHFDDENFDIKHDKEGLLSMANTGPNTNGCQFFIITKKCEWLDGKNVVFGRIIDNDSLILLKKIENVSVTPYIYKPKIAINIVECGEL
Protein: Probable aquaporin TIP5-1 (Tonoplast intrinsic protein 5-1) (AtTIP5;1) (Q9STX9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potential aquaporin, which may facilitate the transport of water and small neutral solutes across cell membranes.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable aquaporin SIP1-2
- Probable aquaporin SIP2-1
- Protein S-acyltransferase 24
- NAC domain-containing protein 91
- NEP1-interacting protein 2
- Probable ADP-ribosylation factor GTPase-activating protein AGD13
- Boron transporter 4
- Urea-proton symporter DUR3
- Aquaporin SIP1-1
- Katanin p60 ATPase-containing subunit A1
Sequence:
MRRMIPTSFSSKFQGVLSMNALRCYVSEFISTFFFVLAAVGSVMSSRKLMAGDVSGPFGVLIPAIANALALSSSVYISWNVSGGHVNPAVTFAMAVAGRISVPTAMFYWTSQMIASVMACLVLKVTVMEQHVPIYKIAGEMTGFGASVLEGVLAFVLVYTVFTASDPRRGLPLAVGPIFIGFVAGANVLAAGPFSGGSMNPACAFGSAMVYGSFKNQAVYWVGPLLGGATAALVYDNVVVPVEDDRGSSTGDAIGV
Protein: Viral interleukin-6 homolog (vIL-6) (Q2HRC7)
Organism: Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Function: Initiates signal transduction through binding to interleukin-6 receptor subunit beta IL6ST, independently of the cognate IL6 receptor IL6R. In infected primary effusion lymphoma cells, promotes proliferation of cells, protects them from apoptosis, and promotes immune evasion of interferon activity. Drives also blood to lymphatic endothelial cell differentiation.
Interaction partners:
Sequence:
MRWFKLWSILLVGSLLVSGTRGKLPDAPEFEKDLLIQRLNWMLWVIDECFRDLCYRTGICKGILEPAAIFHLKLPAINDTDHCGLIGFNETSCLKKLADGFFEFEVLFKFLTTEFGKSVINVDVMELLTKTLGWDIQEELNKLTKTHYSPPKFDRGLLGRLQGLKYWVRHFASFYVLSAMEKFAGQAVRVLNSIPDVTPDVHDK
Protein: Ribosomal protein S12 (Q7JAI8)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- Small ribosomal subunit protein uS14c
- Os01g0220300 protein
- Small ribosomal subunit protein uS2c
- Small ribosomal subunit protein bS16c
- Large ribosomal subunit protein bL27c
- Os10g0411700 protein
- Small ribosomal subunit protein eS19
- Small ribosomal subunit protein uS9c
- Os02g0102400 protein
- Os07g0658200 protein
Sequence:
MPTKNQLIRHGREEKQRTDRTRASDQCPQKQGVCLRVSTRTPKKPNSALRKIAKVRLSNRHDIFAHIPGEGHNSQEHSIVLVRGGRVKDSPGVKSHRIRGVKDLLGIPDRRKGRSKYGAERPKSK
Protein: Protein C-mannosyl-transferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1) (Q2PZI1)
Organism: Homo sapiens (Human)
Function: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A6X919}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MEGRPPPEGRPPPRPRTGRAPRGRRRAVFAAVLHWSHITHLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFAVYVVGYIDICKLRKIIYIHMISLALCFVLMFGNSMLLTSYYASSLVIIWGILAMKPHFLKINVSELSLWVIQGCFWLFGTVILKYLTSKIFGIADDAHIGNLLTSKFFSYKDFDTLLYTCAAEFDFMEKETPLRYTKTLLLPVVLVVFVAIVRKIISDMWGVLAKQQTHVRKHQFDHGELVYHALQLLAYTALGILIMRLKLFLTPHMCVMASLICSRQLFGWLFCKVHPGAIVFAILAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPIVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLKVNYYILEESWCVRRSKPGCSMPEIWDVEDPANAGKTPLCNLLVKDSKPHFTTVFQNSVYKVLEVVKE
Protein: Fatty acid-binding protein, liver (L-FABP) (Liver-type fatty acid-binding protein) (Q6FGL7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369022}.
Interaction partners:
Sequence:
MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI
Protein: Proteasome inhibitor PI31 subunit (Q54S82)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}.
Interaction partners:
- WASH complex subunit 5
- Ubiquitin fusion degradation protein 1 homolog
- Nuclear protein localization protein 4 homolog
- Proteasome subunit alpha type-1
Sequence:
MENFIKERLKSLIGNDNSIGIRDKYDVAVLVIALILNKHEFKLEGGEETNDKVVPTNWNSNADSYTLDLINHLAPGKTFHFKCLRMGNLLLVNAMIKDKNDKIHTLDVDTDKLVKNTEYKDVENLLLNLKEFISIFEYSIINPLVPGLVRIPTNMQEQQPQQQQQQQQQQQQERRPPNNQRDFEDDDPLRVGDPQRGSNRYRGGFNGGGDQDPDLYPPGFPVFGHNPPFYPGQTRGPGVFPGQGGQVGRDHPGFGNIHNPYGGGNNPYGTGLPGYEQRLPRGAVPPGARFDPFGPPTGGIPPSGRGRGMPDRDDFTPPGFDNDHYM
Protein: Cullin-3 (CUL-3) (Q17391)
Organism: Caenorhabditis elegans
Function: Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule stability in the early embryo. In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of microtubule severing protein mei-1 downstream of unc-89. Together with spop-1, may promote the ubiquitination and proteasomal degradation of target bromodomain-containing proteins such as bet-1.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Protein maternal effect lethal 26
- RING-box protein 1
- Ubiquitin-like protein NEDD8
- Kelch-like protein 8
- Speckle-type POZ protein homolog
- RING-box protein 2
- Cullin-associated NEDD8-dissociated protein 1
- COP9 signalosome complex subunit 5
- BTB domain-containing protein
- Defective in cullin neddylation protein 1
Sequence:
MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA
Protein: Trypsin iota (EC 3.4.21.4) (P52905)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Peptidase M14 domain-containing protein
- Bazooka, isoform B
- Zinc carboxypeptidase A 1
- Trypsin zeta
- Uncharacterized protein, isoform A
- Trypsin theta
- Uncharacterized protein, isoform A
- RE65433p
- RE08710p
- LP05863p
Sequence:
MAVYGIVATVLVLLLLGDASDVEATGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHCLHERSVTLMKVRVGAQNHNYGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLSTRAINLASTSPSGGTTVTVTGWGHTDNGALSDSLQKAQLQIIDRGECASQKFGYGADFVGEETICAASTDADACTGDSGGPLVASSQLVGIVSWGYRCADDNYPGVYADVAILRPWIVKAANAI
Protein: F-box protein AUF2 (F-box protein At1g22220) (Protein AUXIN UP-REGULATED F-BOX PROTEIN 2) (Q9LM18)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8LEA8}.
Interaction partners:
- F12K8.23 protein
- Probable protein S-acyltransferase 19
- F-box/WD-40 repeat-containing protein At5g21040
- Cytochrome P450, family 702, subfamily A, polypeptide 6
Sequence:
MDVFDGLPDPIIVDILNKVGDVKTLLRCSSLSKRFNSLVPQSESLTLRLDHSVSDSPVVTSIFRSLFNGLVSLLSKPAKPITITTLSPSLPFKILSRFDRIRNLDVELPGGDVKLEKGAAVKWKAEFGKTLKSCVIVAFRSAGTVSSPVAVEGESDAEFVTGLKTRVVWTISALMAASSRHYLMREVVKEHEEIESLVMRDKEREGTVVMNEEGLKELRNTEARVEDEERVVKNKRSVVPSVRMSMRHAPSLKLKSGICLESATLVIVRPSGADFEVGDDAELATEAFVGDCMYGEAVVALLKCKKNALEMNSF
Protein: Secreted antigen GbpB/SagA putative peptidoglycan hydrolase (Q8DWM3)
Organism: Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Interaction partners:
- Glucosyltransferase-S
- Glucosyltransferase-SI
- Glucosyltransferase-I
- Glucan-binding protein A, GbpA
- Glucan-binding protein C, GbpC
- Biofilm regulatory protein A
- Cell division protein FtsX
- Levansucrase
- Glucan-binding protein D with lipase activity BglB-like protein
- Cell surface antigen I/II
Sequence:
MKKRILSAVLVSGVTLSSATTLSAVKADDFDAQIASQDSKINNLTAQQQAAQAQVNTIQGQVSALQTQQAELQAENQRLEAQSATLGQQIQTLSSKIVARNESLKQQARSAQKSNAATSYINAIINSKSVSDAINRVSAIREVVSANEKMLQQQEQDKAAVEQKQQENQAAINTVAANQETIAQNTNALNTQQAQLEAAQLNLQAELTTAQDQKATLVAQKAAAEEAARQAAAAQAAAEAKAAAEAKALQEQAAQAQAAANNNTQATDVSDQQAAAADNTQAAQTGDSTEQSAAQAVNNSDQESTTATEAQPSASSASTAAVAANTSSANTYPAGQCTWGVKSLAPWVGNYWGNGGQWAASAAAAGYRVGSTPSAGAVAVWNDGGYGHVAYVTGVQGGQIQVQEANYAGNQSIGNYRGWFNPGSVSYIYPN
Protein: Aspartate ammonia-lyase (Aspartase) (EC 4.3.1.1) (P0AC38)
Organism: Escherichia coli (strain K12)
Interaction partners:
- L-asparaginase 2
- L-asparaginase 1
- Phosphoenolpyruvate carboxykinase
- Adenylosuccinate synthetase
- Argininosuccinate lyase
- Adenylosuccinate lyase
- C4-dicarboxylate transporter DcuA
- L-aspartate oxidase
- Isoaspartyl peptidase
- Aspartate aminotransferase
Sequence:
MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLIKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHPAYKAKRYTDESEQ
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (M9PI41)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Kinesin-like protein
- Anillin
- Ras-like GTP-binding protein Rho1
- LP17758p
- Ras-related protein Rac1
- Protein abnormal spindle
- Rac GTPase-activating protein 1
- Fascetto
- RE13502p
- Inner centromere protein, isoform A
Sequence:
MPPKMEPISVRTARLNNLILGKGAGVCAKPAGSASGSGIPASTRRSIVPVSTTSAAVAEAICREGLLDAFCLLYNECDKDTLKKRDRNIAEFVNKFRPIIEETRKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRLSYERIKNHPFFSEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRHKTRREQGVAKKSLTTNMKSNDFSGKDLPFIGYSFVHMEKSAISATTDEKLQEKLKELLQKLKTRENEISMLKQDLLRAQQSLRKTDNKSQVVADAKMEIKKLQQIIKEKTMELTTCKTQIKTLQSSAKIDEEMWSKKEATITDLLRLNRQKYEEAKIASEQRYEKQLADKKQELASTLQKLDARELEFNAKFEECKHLSMKLQNYKDMLQQIKEQNLKSETNHEEQRRQMAELYEQKLTDLRKKVRDSQDTNRRMTMEIKEIRTELDESISSSKSTQEAKNATERNIEEILRRLNEEIASNNELHAEKVKLETKLQLKENETQEVRAECHRLERELQLAECRCQLAESSLATQVSPYETAPGSLTELNAIEDQLRADLLAAKESENHQKGRADQLQTLVTKLEQMLERFNEQSLSPTKSHSSRKQEGETVGDMLERQNEKLEDKLAAVREQMIVERQAARTANLSLWKVEKQLEEALSEKKLLARRMELTEDRIKKVQNASDEAQRMLKTSQEETRQRESRIEELKQELAAAKRDVLKEHRQWEKAEQERMKCKSEIIEHLANVHRLEQQETELRQKLRQIQSRFDGVTLEQKNTIRELQEEREKSRKANDSCLVLQKELKQLTDNFQRLKYACSITDSQLTEVETMLKSEQERNKSQKSQLDTLHEKLRERNDQLTDLRKQLTTVESEKRLAEQRAQVLASEIDELRLNLKEQQKKLVAQQDQLVEQTNALFATQERAELLDGQNANYEAQTADSNREMVSLKEENARILSELFHKKEEVGNLQAEIRGLESAQANLHAEIDSLQDTLAEKEQFYVQRDIKSNATLAQHKKLIDYLQLKVEDLSAKKKKTLADKLFGSSHTNKENVSPNDVESSILYRALKEELKREQKMNSLLKEQLAQLNGTATLRSPRKSAAVNGDSDAPKQRPVSIAALPRSPQKQQQPLKRTTSQVELKTTAEKPTKVTIENQAHHRFELALQESKVDAVNCVVCEKAVVAGSPFWKCKECKDVTHRKCRSNVQSHCGSTKPTAPSADDLSSIQSVSSLTLDSVDVAGGTTSGGEYIGSLVYSSDGAEDQARKEIEVNCAFEVAEQQILLLGCNTGLYAYHLDSQRLVHISGLESVSCMSICKRLAKAIMVGTVGEKLYQCDYRQLESRCQSSSSCHKPVLETSAIELPFANRTPSEKWKLVLISDEAENALDSVAIAATSTRIVILKYDLKLHMFKPVRALDTATPVTSIFFTRHSAIVSSDKFYEIDLDNYAAEEFVDLSDKSMESTAKCQPLTAVRISRQEYLLCFAEYGVFVDEFGCRSRPYDLNWVYAPTGFVYRDPFLFISHYQSVQIVRLHRSFSKEMASGDNASENSESPELQRVYLPHYMSTLLANSGDVNLYAVAIDQRPCNGTQKIYHLDTMQAFKQKFNISMETLSSVATSVTLGSTVTGNSI
Protein: Repair DNA polymerase X (Pol X) (EC 2.7.7.7) (AsfvPolX) (P42494)
Organism: African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV)
Function: Error-prone polymerase lacking a proofreading 3'-5' exonuclease which catalyzes the gap-filling reaction during the DNA repair process. Specifically binds intermediates in the single-nucleotide base-excision repair process. Also catalyzes DNA polymerization with low nucleotide-insertion fidelity. Probably acts as a strategic DNA mutase, which gives rise to a rapid emergence of variants. Generates mismatched G-G pairs, in that case, the polymerase first binds the deoxynucleotide followed by mismatch formation. Together with the viral DNA ligase, fills the single nucleotide gaps generated by the AP endonuclease (Probable). Binds DNA with high affinity via the helix alphaE.
Subcellular location: Virion {ECO:0000269|PubMed:30185597}. Note=Found in association with viral nucleoid. {ECO:0000269|PubMed:30185597}.
Interaction partners:
Sequence:
MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL