wanglab/gogpt-training-data huggingface dataset:
Protein: Uncharacterized transmembrane protein DDB_G0283573 (Q54QV8)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Translocase of outer mitochondrial membrane
- SMP-LTD domain-containing protein
- Mitofilin
- Bacterial surface antigen
- Glutathione S-transferase domain-containing protein
- Uncharacterized protein
- Translocase of outer mitochondrial membrane
- Probable mitochondrial Rho GTPase gemA
Sequence:
MLGRLIKDTTQFVKSSTKFGIVWGPKLAPWGITLGLGAFYFFQPKFLFKPLPIIGSNYLTQKDLDKMKKEAAENSQ
Protein: Probable coatomer subunit gamma (Gamma-coat protein) (Gamma-COP) (P87140)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}.
Interaction partners:
- Coatomer subunit delta
- Coatomer subunit beta
- Probable coatomer subunit beta'
- Probable coatomer subunit zeta
- Probable coatomer subunit epsilon
- Putative coatomer subunit alpha
- ADP-ribosylation factor 1
- ADP-ribosylation factor GTPase-activating protein glo3
- Probable clathrin heavy chain
- Uncharacterized protein C211.03
Sequence:
MSYSKKDDDGDESIFANVNQVTVTQDARAFNSSSISPRKSRRLLSKIAYLIYTGEHFQEKQATELFFGITKLFQHKDPSLRQFVYIIIKELSVVAEDVIMITSSIMKDTATGRETIYRPNAIRSLIRVIDANTVPAIERILTTGIVDPISAVASAALVSAYHLYPVAKDIVSRWNNEVQDAVTSHNVGRKVASSPFFTSTLGYTPNASGISQYHALGLLYRIRRHDSIAMNKLLQLLVSNLGTVSNSHAFVMLIRYISSLMDQNTQFRDQMVPFLHGWLKSKGDMVNLEVARNMVRLKNISDDDLQPVVSVLKIFLSSHRSATRFSAIRTLNELAMTRPHLVHSCNLNIESLITDVNRSIATYAITTLLKTGNDESVDRLMKQIVTFMSDISDNFKIIVVDAIRSLCLKFPRKQDSMLTFLSNILCDEGGYEFKRAAVDAISDMIKYIPESKERALAELCEFIEDCEYPKIAVRILSILGEEGPKASEPTRFIRYIYNRIMLENAIVRSAAVSALTKFGLNAEDKFVQRSVKVILTRCLEDADDEVRDRAAFSVKALEDRDAFLPVVKSDKIPSLPALERSLVIYISERKFGQGFDIKSVPVLSQEEIDAENLRIKKATTEVEFTEVTPAEDQNALASSNIETEFLNALESVSEFNEYGPVLKSSPSPIELTEQETEFVVKVVKHVFKDHLVVQFQLHNTLSEVILENAVVVSTPSTDDLVEECVVPAAIVSGEPVSIFVSFKFNDSVPYPLTTLTNTLQFTTKEIDIHTGEPEEEGYEDEYKIDDLDVSAGDFISPAYESNFDGLFDSLEHEASEVYVLSLLDSFRSTCSRVAELLQMQPLEGTENPTDKPVHVMKLSGKLVNGEKVLALVKMAHSKDGEGITIKVIARGESDSSVELVVGGIA
Protein: STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (Serine/threonine-protein kinase 39) (Q9Z1W9)
Organism: Mus musculus (Mouse)
Function: May act as a mediator of stress-activated signals. Mediates the inhibition of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation. Phosphorylates RELT.
Subcellular location: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. Note=Nucleus when caspase-cleaved. {ECO:0000305}.
Interaction partners:
- Solute carrier family 12 member 2
- Solute carrier family 12 member 1-chloride cotransporter 1)
- Translocation protein SEC62
- Protein transport protein Sec61 subunit gamma
- Solute carrier family 12 member 6
- Kelch-like protein 3
- Calcium-binding protein 39
- Serine/threonine-protein kinase WNK4
- Serine/threonine-protein kinase WNK1
- Translocation protein SEC63 homolog
Sequence:
MAEPSGSPVHVQLSQQAAPVTAAAATAPAAATSAPAPAPAPAPAASAAPAPAPAAAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAASQEKSRRVKEENSEISVNAGGIPEQIQSLSVHDSQAQPNANEDYREGPCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
Protein: Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl (EC 2.7.1.68) (Protein Skittles) (Q9W2R3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18948416}. Cytoplasm, cell cortex {ECO:0000269|PubMed:18948416}. Nucleus {ECO:0000269|PubMed:15280236}. Chromosome {ECO:0000269|PubMed:15280236}. Apical cell membrane {ECO:0000269|PubMed:23853710}; Peripheral membrane protein {ECO:0000269|PubMed:23853710}; Cytoplasmic side {ECO:0000305}. Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:20237161}. Note=Accumulation on polytene chromosomes requires ash2 (PubMed:15280236). During spermatogenesis localizes with, or near to, ring canals at the growing end of spermatid cysts in a PtdIns[4,5]P(2) dependent manner (PubMed:20237161). {ECO:0000269|PubMed:15280236, ECO:0000269|PubMed:20237161}.
Interaction partners:
- Phosphatidylinositol 4-kinase alpha
- Phosphatidylinositol 4-kinase beta
- Phosphatidylinositol 4-kinase type 2
- Phosphatidylinositol-3-phosphatase SAC1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- EG:86E4.5 protein
- phosphatidylinositol 3-kinase
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
- phosphoinositide 5-phosphatase
Sequence:
MDTRVELELEPVGKQDRLKDQPDDENEPLENQLELEQEHKSLLTPVKIPPAQTASPDQEATPSTPPPMSLQPGTSRQLFRDAAMAHGGQETTSLLQQELNNIAATQTPASKLRSASSTLDASISRNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQSKQIMGSIQLGIQHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAPDDFLMSMCASPLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQNPRTLLPKFFGLYCFHYNSKNVRLVAMNNLLPSDIKMHCKYDLKGSSFRRKASKAERQKASPTFKDLDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQRLVAHSTALESITADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHTFKSILYNGDTVSVCRPSFYAKRFQDAMGKQVFKKTPTFPLKHSPSKRKTSTTQLRSPASRLPPLSTPTNAVRQPIMTMSGMSTPPPAFDDISEEDITAASTSSLQQQRSSNQSNNNRGETEVALREGNNTRGGSGEPSSTYHTQYSYDSSGRTGSALTSDYSDDESTGTDLSSRLPKLRTHRLTKTSVQVTTVGYVEGVDTPPKGGQDVVHADVNGKTTMTTTTMLTTTKTAHIQAPSYTSTLVLNDLPR
Protein: Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase (RPnTP diphosphatase) (EC 3.6.1.63) (P16689)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the hydrolysis of alpha-D-ribose 1-methylphosphonate triphosphate (RPnTP) to form alpha-D-ribose 1-methylphosphonate phosphate (PRPn) and diphosphate.
Interaction partners:
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG
- Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH
- Putative phosphonates utilization ATP-binding protein PhnK
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI
- Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL
- Ribose 1,5-bisphosphate phosphokinase PhnN
- Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
- Probable transcriptional regulator PhnF
- Phosphonates import ATP-binding protein PhnC
Sequence:
MIINNVKLVLENEVVSGSLEVQNGEIRAFAESQSRLPEAMDGEGGWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVRDGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVQREPVTLVSLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAALCRARKIALASHDDATHAHVAESHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVRGGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDQSNRFTLPQAVKLVTKNPAQALNLQDRGVIGEGKRADLVLAHRKDNHIHIDHVWRQGKRVF
Protein: Very-long-chain aldehyde decarbonylase GL1-4 (EC 4.1.99.5) (Protein GLOSSY 1-4) (Q6K9F6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes. Core component of a very-long-chain alkane synthesis complex.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:F4HVY0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F4HVY0}.
Interaction partners:
- Very-long-chain aldehyde decarbonylase GL1-7
- Very-long-chain aldehyde decarbonylase GL1-3
- Very-long-chain aldehyde decarbonylase GL1-2
Sequence:
MATRPGPLTEWPWHRLGNFKYVVMAPVVAHGARRVMRNGWGDLDIAFSLILPSLLLRMIHNQIWISLSRYQTARSKHRIVDRGIEFDQVDRERGWDDQILFNGLVFYAGYLAMPSVRRMPVWRTDGAVVTALVHTGPVEFLYYWFHRALHHHFLYSRYHSHHHASIVTEPITSVIHPFAEHVVYFILFAIPILSTIYLGNVSAMGIVGYIAYIDFMNNMGHCNFELVPEWIFQIFPPLKYLIYTPSFHSLHHTQFRTNYSLFMPFYDYIYNTMDKSSDELYESSLKGTEETPDLVHLTHMTNLQSAYHLRIGIASIASKPYSDSAWYMWTLWPLAWLSMVLAWIYGSSAFVVERIKLNKMKMQTWALPRYNFQYGLTWEREPINDLIEKAILDADMKGVKVISLGLLNQAKQLNGNGELFRQKYPKLGVRIIDGSGLATAVVLKSIPSDAKKVFLRTGTSKIARAIAIALCDRGVQVIMNEKEVYHMLKSQIPENRASYLKLSSDNVPQLWIVHNIDDNEQKMAPKGTIFIPISQFPLKKLRKDCTYMSTPAMRIPEEMKNIHSCENWLPRRVMSAWHIAGILHALEGWNMHECGDEMMDIEKSWSAAIRHGFLPLTKA
Protein: Transcription factor btd (Protein buttonhead) (Q24266)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for the development of the antennal, intercalary and mandibular segments of the head.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Homeotic protein empty spiracles
- Homeotic protein ocelliless
- histone acetyltransferase
- FI24210p1
- Taiman, isoform G
- Mediator of RNA polymerase II transcription subunit 1
- Peptidase S1 domain-containing protein
- Protein nubbin
- Mothers against decapentaplegic homolog
- Homeotic protein distal-less
Sequence:
MIDAACNYLNPYAQQHQAQQQQHAQHQQHAQQQQHHLHMQQAQHHLHLSHQQAQQQHMQHLTQQQQQQQQQQQQQQQQQQQQQQPQQQQHDFLSAAALLSAPPSLSGSSSGSSSGSSPLYGKPPMKLELPYPQASSTGTASPNSSIQSAPSSASVSPSIFPSPAQSFASISASPSTPTTTLAPPTTAAAGALAGSPTSSSPSSSAASAAAAAAAAAAAAADLGAAAVASAAYGWNTAYSGLGPARSQFPYAQYASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYPGFNFDDIAFQTQLQRRSVRCTCPNCTNEMSGLPPIVGPDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPFLCLTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTHFKDKKSKKVLAAEAKEQAAAAIKLEKKEKKSGKPLTPPVEFKQEQPDTTPLVNYAPYANLYQHSTSAGSSVNPPPPPPPLFQQQMTTTTSSAAASFVEQPWSSSSSRAIQPATTSASSSSSSSASSPAAAVVSAIGSASSPAASATALAQHHYAALAMQSESQLAAEYGLTMSGLASGASQDSSSSCHMKSEYAASYPADFGAGTASYGYPHPHPHHHNAWAAAYHPHATA
Protein: Ent-copalyl diphosphate synthase 5 (EC 5.5.1.13) (Putative ent-copalyl diphosphate synthase) (IrTPS1) (A0A1X9ISN9)
Organism: Isodon rubescens (Rabdosia rubescens)
Function: Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities. Catalyzes the conversion of (2E,6E,10E)-geranylgeranyl diphosphate (GGPP) to ent-copalyl diphosphate (ent-CPP).
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
Sequence:
NQLADGSWGDAGTFSIFDRILNTLACVVALRSWNIHPHKTDKGIWFMKKNMCRIDEENLEHMPIGFEVALPSLIDIAKKLEIDIPTQTRGLQEIYARREIKLKKIPRDIMHQVPTTLLHSLEGMAGLKWEKLLKLQSEDGSFLFSPSSTAFALQQTRDHNCLKYLTNHIHKFNGGVPNVYPVDLFEHLWAVDRLQRLGLSRYFEPEIEECIAYVHRQWTEKGICWARNSQVEDIDDTAMGFRLLRLHGYEVSADVFRHFKSDGGEFFCFKGQSTQAVTGMYNLYRASQLMFPGENILVDAARFSANFLQLKRAKNDLLDKWIITKDLPGEVGYALDVPWYASLPRVETRFYLDQYGGDDDVWIGKTLYRMPYVNNNKYLELAKLDYNNCQALHQQEWQNILKWYRSCSLGEFGMTERSLLQTYYVAAASVFEPEKSQERLAWAKTAILMETITSHFEFQQLSRDQKRAFITEFEHDSILKYTNGGRYKRRSSLVGTLVRTLNHLSLDILLAHGRDIHQPLKNAWCKWLNSWEEGGDAELLVRTLNLMSGGGRRRRWASEELLSSNPKHEQLLKATIGVCDKLRLFLRRKVQGGNGCMNATGMTTVEIESEMRELVKLVVTRSSSEDLDSEIKQNFLTIARSFYYAAYCNQGTINFHIAKVLFEK
Protein: Maternal embryonic leucine zipper kinase (zMelk) (EC 2.7.11.1) (Protein kinase PK38) (F1QGZ6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Also plays a role in primitive hematopoiesis, possibly by affecting the expression of genes critical for hematopoiesis.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Interaction partners:
- BUB1 mitotic checkpoint serine/threonine kinase
- Discs, large
- Lymphokine-activated killer T-cell-originated protein kinase homolog
- Kinesin family member 4
- Kinetochore protein NDC80 homolog
- Forkhead box M1.
- Cell division cycle 20 homolog
- TPX2 microtubule nucleation factor
- Kinesin family member 11
- Baculoviral IAP repeat-containing 5a.
Sequence:
MPVDSTSELLKHYEVYETIGSGGFAKVKLGRHKLTGEKVAIKIMEKKDLGDDLPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFGLCAKPKGGLGFELLTCCGSPAYAAPELIQGKAYIGSEADVWSMGVLLYALLCGFLPFDDDNCMVLYRKITRGKYSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLDHPWVMRGYSTPVEWHSKYPLGHIDEDCITEMAVTFKQSKQRTIQLVSEWKYDQITATYLLLLAKKRQGRPVRLRAECPVIDIVCSPLQDMQLKKSLRFTEDDDGVHPVVLGSMVFPPDCYDDENPWTPLTPKNTHTTNTPRMKLYPETTEKWNEMAYSPVIEHSRPCRQKPERRERTKENKENLAVPGTDGDVFALPAPRTPTSSRKVKSNRTVMTTPNHNNNKSSEVNKGAGSATKEGSRRREVEQQQNGQQGELNILAFSPERRSRSLDLAGCQVDSGQKRKGGKVFGSLERGLDKVITMLTPSKKRGPRDGPRKIKAQYNVTLTNQTNADQVLNQILSILPEKNVDFVQKGYTLKCHTQSDFGKVTMQFELEVCLLQKPEVVGIRRQRLKGDAWVYKHLVEDILSSSSQWSA
Protein: Multiple C2 domain and transmembrane region protein 13 (Q9LZE5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000269|PubMed:29259105}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:29259105}.
Interaction partners:
- 16 kDa phloem protein 2
Sequence:
MAANKDEFSVKQISPKLGGERGARNPYGPTSLHDLVEQMEFLYVDVIRAIKNSDVDPGPCDPVVEITLGNYKSSTKDLPVGPNMDWNQVFAFDKTKGDVLSVTLKDRLTNTVINKSNFKLASEIPTRAPPDARIAPQRYPLRNTKTGFYLMMSVWFGTQVDEVYPVAWFSDASEVSTCVINTRPKVYLAPRLCYVRVTIVSGHDLISTDRNRTPSVYVTATLGQVTLKTEVSSGTNPSWNKDLIFVASEPLEGTVYIRLIDRVDDQHEERIIGKLEKKLSEMTPLKVPSSAPALFYDIEVEPAGDSRRFASRLKMKLATDQAYHVAEESIQYSSDYRPFVKGLWPCLLGKLEIGILGATGLKGSDERKQGIDSYVVAKYGNKWARTRTVVNSVTPKWNEQYSWDDYEKCTVLTLGIYDNRQIFKEDQANDVPIGKVRISLNRVESDWIYACSYPILKLGSSGLKKMGELQLAVRFVYVAQGYARYSAPFRWLLPKAHYKSPLSVYQIEEMRAEAVKINCANLARTEPALRNEVVWDMLKPKTNTRYSTCDMRKVAALAFFDLFLYWPSLIVWLAIYLVVVPCIVLVGLSGLHKFLTRKFWNKRENPRSPLIVNDLKLWKLESPNLDELEEEFDSFPSSVSDVNILRMRYDRIRMVCQRPMILLGDAASQGERLYALLTFNGDDQLASFYCWLICVLVALCWYNIPMWLWSLYPIAYWLNFTPLRNDMPCGVSNFFRRLPTNEVLF
Protein: Prostaglandin E receptor 4 (Subtype EP4) c (S6B1G5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MEKRSVDFAEPLVNLSYINDSLLNVSEVFVNFSNSSSRALSLDFRSLVTSATMFGVGVLGNLVAIVVLCISKKEQKETTFYTLVCGMAITDLLGTCFTSPVVIATYIAGRWPGGALLCHFFSFSMLFFGSAGMSILCAMSVERYLAINHAYFYSQHVDRAMARFALMATYLANIVLCIMPSFGFGKHKRHFPGTWCFLDWRAMDSVGASYTFLYGGFMLLLIAVTVLCNFAVCRSLVGMSKMSRMVRAEVPGHAGSRRGFRLTSAAEIQMFWLLILMTIVFLICSIPLVVRIFVNQLYDPAYISSGKSPDYRSDLLAIRFASFNPILDPWVYILCRKNLLTKGCARLKRTIRHRKGDHSRVLGWTDGQHSPPSLVQSNCTSYASLRTAICRNDVGKQNCMNTKSYLDLTLRQAWDFDTALAQFHPFSVEQNTVMGFDEDEATSSPKLIAKTVMALPATQILENKAEIVTCTFSTPSSCLSEKCMRQ
Protein: Rapid alkalinization factor (NtRALF) (Q945T0)
Organism: Nicotiana tabacum (Common tobacco)
Function: Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases. Prevents root growth and seedling development in heterologous system.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MGVPSGLILCVLIGAFFISMAAAGDSGAYDWVMPARSGGGCKGSIGECIAEEEEFELDSESNRRILATKKYISYGALQKNSVPCSRRGASYYNCKPGAQANPYSRGCSAITRCRS
Protein: GH09623p (Uncharacterized protein, isoform A (EC 2.4.2.3)) (Q9VBA0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uridine kinase
- Uracil phosphoribosyltransferase homolog
- Uridine 5'-monophosphate synthase
- Cytidine deaminase
- cytidine deaminase
- Cytidine deaminase
- purine-nucleoside phosphorylase
- Dihydropyrimidine dehydrogenase [NADP
- Carbohydrate kinase PfkB domain-containing protein
- FI09636p
Sequence:
MPPTITDNQTHDFKAHYDCAHRSSLQDDETDDAYVKRITRYSDGTVKLRNSNIELMDQDILYHLALGSESHDLQEMFGDVKFVCMGGTPKRMENFAHFIMNEIGYKLPAGTQLQDISAYSYRYSMYKVGPVLCVSHGMGTPSVSILMHEMIKLMYHAKCKDPVFIRIGTCGGIGVDGGTVIITEDALDGQLRNSHEFTILGKTIHRPAKLDKKLARELKSLASPDDPYDTIIGKTLCTNDFYEGQGRLDGAFCDFSENEKMAYLEKLRENGVVNIEMESTIFAALTHHAGIKAAVVCVALLNRLNGDQVNAPKEVMNEWQARPQILVSRYIRKVLTHNGQLKALFGHQGSIKSPRRFKLVQQESQAHE
Protein: UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing) (EC 3.2.1.184) (Q5ZXH8)
Organism: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Function: Involved in biosynthesis of legionaminic acid (5,7-diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into virulence-associated cell surface glycoconjugates such as lipopolysaccharide (LPS) which could be a key determinant in the ability of L.pneumophila to inhibit the fusion of phagosomes with lysosomes. LPS contains a majority alpha2,4-linked homomer of legionaminic acid. Catalyzes the conversion of UDP-N,N'-diacetylbacillosamine (Bac2Ac4Ac) into 2,4-diacetamido-2,4,6-trideoxymannose and UDP.
Interaction partners:
- N,N'-diacetyllegionaminic acid synthase
- GDP-perosamine synthase
- CMP-N,N'-diacetyllegionaminic acid synthase
- Acetyltransferase
- LPS biosynthesis protein, PseA-like
- dTDP-glucose 4,6-dehydratase
- Spore coat polysaccharide biosynthesis protein E
- dTDP-4-dehydrorhamnose 3,5-epimerase
- Aminotransferase
- imidazole glycerol-phosphate synthase
Sequence:
MIRKIIYVTGTRADYGLMREVLKRLHQSEDIDLSICVTGMHLDALYGNTVNEIKADQFSICGIIPVDLANAQHSSMAKAIGHELLGFTEVFESETPDVVLLLGDRGEMLAAAIAAIHLNIPVVHLHGGERSGTVDEMVRHAISKLSHYHFVATEASKQRLIRMGEKEETIFQVGAPGLDEIMQYKTSTRDVFNQRYGFDPDKKICLLIYHPVVQEVDSIKIQFQSVIQAALATNLQIICLEPNSDTGGHLIREVIQEYIDHPDVRIIKHLHRPEFIDCLANSDVMLGNSSSGIIEAASFNLNVVNVGSRQNLRERSDNVIDVDVTYDAILTGLREALNKPKIKYSNCYGDGKTSERCYQLLKTIPLHSQILNKCNAY
Protein: Fates-shifted (A1Z9A5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Dampened, isoform A
Sequence:
MSFDADCDEFIKNKLFRSKGKCDIYARQSDVCVAVKQKSTFRATAPTLPMAEGNNNNVISMRYDIWFHISMHIDPEDVQTFALICKQTSRLVASRAFWRNLYRRHCTGATSGWNLNLPAELQLESIRNCKTRALKSLVIAALFHCHRPLKVRLELGYNLDWMLQRIFVSCFQTHYQCLWIMCYKFWNRQSHEQDETETHTGEVVNDWESLADDDATKLAPTFCNPHEGVVLLVVICRHFVPTSNHLAYGPQQQRYRLRATRELLCTDMRAKNLELDFAEDGCRNVSVTVKHDRIEKYKVLPWWHPDFQRFVK
Protein: V-type proton ATPase subunit E (V-ATPase subunit E) (Vacuolar proton pump subunit E) (O13687)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
Subcellular location: Vacuole membrane {ECO:0000250|UniProtKB:P22203}; Peripheral membrane protein {ECO:0000250|UniProtKB:P22203}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase subunit d
- V-type proton ATPase subunit B
- V-type proton ATPase subunit a
- V-type proton ATPase subunit c
- V-type proton ATPase subunit C
- V-type proton ATPase subunit D
- Probable V-type proton ATPase 20 kDa proteolipid subunit
- V-type proton ATPase subunit H
- V-type proton ATPase subunit F
Sequence:
MSLSDEQVQAEMHKMVSFIKQEALEKAKEIHTLSEEEFQVEKAKIVREQCDAIDQTYDMKLKRASMAQKIAKSNVLNKSRLEILNSKQKVIDDIFSRVEKKLDGIEQKKDAYTKFMADLIVQAMELLGEPVGIVYSRQRDAEIVKAAIPKATEVLKSKNGSIDYELDAETDDFLNDSVLGGVVLVGLGGKIRVDNTLRARLEIVKEEALPEIRRLLFGENPNRKFDN
Protein: Transcription factor MYB59 (Myb-related protein 59) (AtMYB59) (Q4JL84)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:16531467}. Note=Isoform MYB59-2 and isoform MYB59-3 (harboring both NLS1 and NLS2) are nuclear, werheas isoform MYB59-1 (harboring NLS2) and isoform MYB59-4 (harboring NLS1) are partially nuclear.
Interaction partners:
- At5g60520 protein-like protein)
- Protein NRT1/ PTR FAMILY 7.3
Sequence:
MKLVQEEYRKGPWTEQEDILLVNFVHLFGDRRWDFVAKVSGLNRTGKSCRLRWVNYLHPGLKRGKMTPQEERLVLELHAKWGNRWSKIARKLPGRTDNEIKNYWRTHMRKKAQEKKRPMSPTSSSSNCCSSSMTTTTSQDTGGSNGKMNQECEDGYYSMDDIWREIDQSGANVIKPVKDNYYSEQSCYLNFPPLASPTWESSLESIWNMDADESKMSSFAIDQFPLSFEHGSGRL
Protein: Protein kinase C-like 1 (PKC 1) (EC 2.7.11.13) (P24583)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for cell growth and for the G2->M transition of the cell division cycle. Mediates a protein kinase cascade; it activates BCK1 which itself activates MKK1/MKK2.
Interaction partners:
- GTP-binding protein RHO1
- Serine/threonine-protein kinase BCK1/SLK1/SSP31
- RHO1 GDP-GTP exchange protein 2
- Protein SLG1
- Serine/threonine-protein kinase PKH2
- Serine/threonine-protein kinase PKH1
- 1,3-beta-glucan synthase component FKS1
- Serine/threonine-protein kinase PKH3
- Regulatory protein SWI4
- M-phase inducer phosphatase
Sequence:
MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLRYTGFQCQDCKFLCHKKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPSVLTTSQQEEFRGFSFMPDDLDL
Protein: Spliceosome-associated protein 49 (O14102)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Pre-mRNA-splicing factor sap61
- Pre-mRNA-splicing factor sap145
- Pre-mRNA-splicing factor prp12
- Pre-mRNA-splicing factor ini1
- Pre-mRNA-splicing factor sap114
- Pre-mRNA-splicing factor sap62
- Uncharacterized protein C211.05
- U2 snRNP component prp10
- U2 snRNP component ist3
- Pre-mRNA-splicing factor dre4
Sequence:
MSIREDRNQDATIYLGNLDEKVTDSILFELCLQAGPVVNIHIPRDRVRNSHNGFGFCEFLHEQDVEYACQILNQVKLFGKPIRVNRASQDRGVNTLIGANLFVGNLDPLVDERVLYDTFSALGQLVKAPQVARDENGRSKGYGFVSYDSFETADAAIEAMNNQFLMNKPITVSYAFKREGKGERHGDIAERKLAAAAKKNKVAVTPQSTLPPGFSPATPAPTSAANTPATIAATSIPPVPNVPLVGATTAVPPLSIPNVLPFTAAQHFPGMPAMPMMNVPMGPGGAPLVPPPPPGMVMASPSPAAATIPGAPVMPNIPFYQTINAQNGYSQQQRR