wanglab/gogpt-training-data huggingface dataset:
Protein: Dihydroxyacetone phosphate acyltransferase, putative (EC 2.3.1.42) (Q583Z3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}.
Interaction partners:
- Alkylglycerone-phosphate synthase
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate acyltransferase, putative
- Lipin, putative
- Phosphatidic acid phosphatase protein, putative
- Phosphatidic acid phosphatase, putative
- Phosphatidic acid phosphatase alpha, putative
- Uncharacterized protein
Sequence:
MKQGNGATHSIPHNVPFRRIVILSDYGSPWLNAVTAVTCATLPCLSALSNGWCEKRGNVVVASKLDSPRVLIPAEAGVAPDGTSCSSLSSLSAVCRDLADGRNIASRIFFTADAASNPRAQTFAPSVEDDLFVYVSAWSGEKDAAHLALRSLSNMFGATSFGIGASGVLTGPCGVPRLIILADESTRNSVCETARHLSNWCVLSCIVPSFAPPAFNHQLAASVVRECDVVCGVLECVALGVALGTVKRLPFGFMDPVCVMPLDAAISTALIAFLQRLKGGPAAVCGGTSATIIIGSPSDSAFVWGMFAQYLMDYYGRVGLLALKESQLRWLFDTSPALQLNADFMNWVNYGTSTMMPFRCYYDNAAARRRKQLMEHYPHSNVARKVCGTLTNIDTRIHNMVKLTQHSEPTGQHDGERVNKQGKPNTAGFYSDLLRAVEQDAALRPLYPYISLSCIRWDVFVKVIAQSVLEHAARQIAGHPTVVPPPLPLYHNDIIFYGPQRAPRNCLLTRFFPESVRWAQRSGLRPNGVLVAAEPGLTEESLACILQRPSIIQVVKKTAKAEGVTEEDVLRRATAILRGMGDNLNQLNVRVFGLMVRKALFRLFDRVSLNASAFERLHAATTQPRTHVMLLPAHRSYIDFIIMTYLLLVMGLTLPHVCAGDDFLRMGQITKLMRGSGAFFIRRTFRDDPLYTALFKEYIHNLVLRKQMIEFFIEGTRSRTGKTQRPMLGVLKFIADTLVNAQEAIDDVCILPVSLSYDELLETKLYAAEQLGLSKPRESVGNLVRASSVLSRRHGKIHVHVAEPLSLRSFCHNPSQCPEGFEPVTGGVTAAAPNKSSDGEGARSPSHIPKQVLTNIAWHVTHTLQDNTIITPTALLAAVLGTLSPPAGCMSLREAQAKMLWLRDHIIRRRAHVSEDCVNNNGEELSRMALFHLAEFVETRVEAGETWVAMRQDSRAPLGVAICSNQLIHVFVDEGVVALVARASGELSDNKKTARVSTDLLKRECELLRTLLAGEFQDYLPWCPYTYASWFKYAVTRLLAHDDIHNDGTVTLEGGGSAESTNKVKKGGTYAVASEPRLHDSEDIVIHFTRRFRFITGILYPFVESLYVVSVAVAAVAETHVEHLLRRRPLLLACQKWALELCNEKRLVVHIQSCGSVALKSAFTSIMEFIGLKSRTEEKDLVYILPIPPNGLETQLQPVTEQLKKLLRPLIEVKEEEEREARNHMVNVYKKIQMSSKRASRM
Protein: Transcription factor SFP1 (Split finger protein 1) (P32432)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Transcription factor that regulates ribosomal protein (RP) and ribosome biogenesis (Ribi) gene expression in response to nutrients and stress. Promotes RP gene expression under optimal growth conditions. Leaves the nucleus upon environmental challenges, resulting in a down-regulation of RP gene transcription. The effect of the environmental cues on SFP1 localization is mediated through the TOR pathway. Also regulates the expression of genes involved in the G2/M transition during the mitotic cell cycle and the DNA-damage response. Required for carbon-source modulation of cell size.
Subcellular location: Cytoplasm. Nucleus. Note=Nuclear under optimal growth conditions. Leaves the nucleus in response to stress or changes in nutrient availability. The [ISP+] aggregates appear to be nuclear.
Interaction partners:
- Protein IFH1
- Rab proteins geranylgeranyltransferase component A
- Pre-rRNA-processing protein FHL1
- Serine/threonine-protein kinase SCH9
- Protein STB3
- DNA-binding protein RAP1
- High mobility group protein 1
- Zinc finger protein MSN2
- Transcriptional regulatory protein TOD6
- SAGA complex/NuA4 acetyltransferase complex subunit TRA1
Sequence:
MDFTTMTMASNMATSTTTTATSAHASINSSSNFNIDIDSNQNTPSILINNNSDSSNGKNTDFNGVNNIHQKNIMNNTNNVHLYSPNIMDQTLLTPQDIAKLRRESIAHSQGMGGVSWGSISVGSWLRDEIISRRNSIVPASANGAASAAASATTTATNTLQIQQPTKRPSVSNPPYHRGYSISPQIAYTAYLPNLEKQYCKDYSCCGLSLPGLHDLLRHYEEAHISTSPNTTNMSQIPMNSAGNTSSSVRMTNNTSSANYNLQNNMAANTKNAGHKTNTMQAHSSNATNNTSINNMHANLQSNMDSNSTIRQSQHPHHQQNIIQQQLQSNSVNHTSGAVPTPSVMGSATASSTTANPNVISITGAPNSGLSMANHSQQLHLNGNLVDAVSTNDVFLRTSNSPSRHVPHNKQINSNNNSGININNNTSHNSNINMGSKNAMVNRPHTFNNYSLNKTSRNPIQHQSRKIDPHQTDLSPLVLVQDIDLSFMDDDILGPSNHNSMNSVVNPTTGSHNYNTFHSSVHAKSSQNMVEDQDIDDIDDDDDVDDDDDDDDDDDTENGSSSNGKSVHNNNYKMPQQAYIDDPARRLYVMDHEEQKPFKCPVIGCEKTYKNQNGLKYHRLHGHQNQKLHENPDGTFSVIDPDSTDSFGDGMGSAKDKPYRCEVCGKRYKNLNGLKYHRGHSTH
Protein: Histone H2B type 1-B (H2B-clustered histone 3) (h2B-143) (Q64475)
Organism: Mus musculus (Mouse)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H3.1
- Histone H3.2
- Histone H3.3
- Histone H4
- E3 ubiquitin-protein ligase BRE1A
- Plasminogen
- E3 ubiquitin-protein ligase BRE1B
- Histone H2AX
- Histone H3-like centromeric protein A
- Breast cancer type 1 susceptibility protein homolog
Sequence:
MPEPSKSAPAPKKGSKKAISKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
Protein: IP11926p (Q9VBT2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPENADTEQFNADELEAPAWLNAQFITDVLRTYEKCPELEVTDLKITPASAQGDHYASVMFRTTAEYTTSKGKFCKPLIIKTMPEQEGHKKDMLSDSHLFSTEINAYTKALPEFERILREAGDDTKLFVPCIYHSLEPRQVLIFEDLVPQGYFVIRDRPINMNEYKNVFSKLAKWHAVSMKVLNEQPDILKDFKYGLMEMPSIMSDPMVTTGMDNFLKMMDQIPELTKYKPHFEKIKENYIQRMGDVMQEYRKNVQSDGYYVMCHGDFHGRNMMFNKNEEVMFVDFQICNLCPITIDLSYSVYMLMEPEQRWDLGKDLINFYFSVLEDTLKKVGYKGKMPTNDGLWKQIHRHKFYDFFLLTTFSPMIVAVKANTFKIHELIQDPEIRQKSYLYDPYVQDVKKLLGKYEEMGYFNDL
Protein: Uncharacterized protein (F4IGM4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAAISPVQCLFSCNSHHHHQQREQSGSLWRLGSRVLVSSSLWKLSLFSGLHLNRRRTLICAVKGDPEDAFKKTVEIDRMIDALRDANPRQVEKIVVENILAFDEVFWIRLAARSDTCKSEDDKKDYEELATTVMTIVDCVVNKTREKIETSTDILKGILRPAIDGVEEISWPPRDPEAINLMKKEIIQREKEGQLDEGFLSEVNAQLRQAKEDKDKPGLLAMLQKVLQLYSATILSKRSYAKKGNEVVKAEHFLETLIKGLFCNHFSMYYRPQPDFTSVYYVCFSS
Protein: Trehalase (EC 3.2.1.28) (Alpha-trehalose glucohydrolase) (Q6FWN0)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- alpha,alpha-trehalase
- Candida glabrata strain CBS138 chromosome G complete sequence
- Candida glabrata strain CBS138 chromosome H complete sequence
- Candida glabrata strain CBS138 chromosome J complete sequence
- Trehalose-6-phosphate synthase
- Trehalase
- Protein ATC1/LIC4
- Protein BTN1
Sequence:
MPTLTFYLGADDAVDGGVKSKSMAFSDPFHKNVKVQSPEPEPVDAKEKKKLNRTRTMSVFYNVADFKDDEEIRKHKLKRRASEDDTYISSKGTRRLFVKDVDWTLKELLQNEDTDQNFQITVEDTGPKVIKLGTANSAGYNHIDIRGTYMLSNLLQELTIAHNFGQRQLYLPESRLNENPVHRLKRVIETHFWDGLTRRLDLNTIGEAAQEKKIDTPEAKNPRVYVPYDCPEMYEYFIQASQMNPSVKLEVEYLPKDITPEYVQSLNETPGLLAIAMDKHVNPTTGETSLVGFPYVFPGGRFNELYGWDSYLITLGLLASKRTDLARGMVEHFIFEIEHYGKILNANRTYYLCRSQPPFLTDMANVTFNGMGGNKNPIAVDLLRRAFRAAIKEYKTVWMAKPRLDEKTGLSCYHPDGVGIPPETEPEHFDTKLRPYAKKYNVTIPEFRRMYNAKEVHEPELDEFFLHDRGVRESGHDTTYRLEGVCAYLATIDLNSLLYKYEVDIANFIKEFCNDKYVDPYDKSVTTSEDWMNLANKRKERIKFYMWDEEAGFFFDYNVKTEKRTSYESATTFWAMWAGVASPQEAEIMVKKAVPKLETLGGIVACTESSRGPIAIDRPYRQWDYPFGWAPHQILAWKGFSNYGYDNIARRLVYRWLYMMTKAFVDYNGIVVEKYDVTKVTDPHKITAEYGNQGVDFKGYAREGFGWVNSSFLLGLQYLDNHAIRALGACIPPKPFLNGLRAKEKARYGL
Protein: cAMP-dependent protein kinase catalytic subunit beta (EC 2.7.11.11) (G1SK25)
Organism: Oryctolagus cuniculus (Rabbit)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004635}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSVKEFLAKAKEDFLKKWENPPPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFCEF
Protein: Zgc:153267 (Q08CC6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MQSAGFLLLCVPLISLLCESILSLPTGKTPTGEFPESVTARSCRELLKKYGHKKDGLYYLRSKDNEVYQTYCDMSTNGGGWTLVASVHENNIHGSCTVGDRWTSQQGSSSYHPAGDGSWSNKVLFGTAEAATNDDYKNPGYYDIKAKDIAVWHVHNDNELEFWKVASVLRYHTNSNFLTPFGGNLYHFFKKYHLQYGIGTCNDRGISVPIVYDIGSDMRVNELYGESVRADFDTGYVTFRVFNYYQEAYAMCSGVRPKGCYAQYYCIGGGGYFPNTFCSDFSYLNANNGATNGYGASKEIINAAVFIFYR
Protein: DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) (Q9QUG2)
Organism: Mus musculus (Mouse)
Function: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9UBT6}. Note=Detected throughout the nucleus and at replication foci. Recruited to DNA damage sites in response to ultraviolet irradiation: N6-methyladenosine (m6A)-containing mRNAs accumulate in the vicinity of DNA damage sites and their presence is required to recruit POLK. {ECO:0000250|UniProtKB:Q9UBT6}.
Interaction partners:
- DNA repair protein REV1
- Proliferating cell nuclear antigen
- DNA polymerase zeta catalytic subunit
- Mitotic spindle assembly checkpoint protein MAD2B
- Cellular tumor antigen p53
- DNA polymerase delta subunit 2
- DNA polymerase iota
- DNA polymerase epsilon catalytic subunit A
- DNA repair protein RAD51 homolog 1
- DNA polymerase eta
Sequence:
MDNTKEKDNFKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIDTPRQEANELTEYERSISPLLFEDSPPDLQPQGSPFQLNSEEQNNPQIAQNSVVFGTSAEEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDGERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLMGVRMSTFSSEDDRKHQQRSIIGFLQAGNQALSSTGDSLDKTDKTELAKPLEMSHKKSFFDKKRSERISNCQDTSRCKTAGQQALQILEPSQALKKLSESFETSENSNDCQTFICPVCFREQEGVSLEAFNEHVDECLDGPSTSENSKISCYSHASSADIGQKEDVHPSIPLCEKRGHENGEITLVDGVDLTGTEDRSLKAARMDTLENNRSKEECPDIPDKSCPISLENETISTLSRQDSVQPCTDEVVTGRALVCPVCNLEQETSDLTLFNIHVDICLNKGIIQELRNSEGNSVKQPKESSRSTDRLQKASGRTKRPGTKTKSSTLKKTKPRDPRHTLDGFFK
Protein: Endoplasmic reticulum protein SC65 (Leprecan-like protein 4) (Nucleolar autoantigen No55) (Prolyl 3-hydroxylase family member 4) (Synaptonemal complex protein SC65) (Q92791)
Organism: Homo sapiens (Human)
Function: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:23959653}.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase B
- Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
- Peptidyl-prolyl cis-trans isomerase FKBP10
Sequence:
MARVAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPAAKPDPDGGRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPPRQLLRDFQSRLPYQYLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALSEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAMLYHNQTAELRELLEFTHMYLQSDDEMELEETEPPLEPEDALSDAEFEGEGDYEEGMYADWWQEPDAKGDEAEAEPEPELA
Protein: Mogroside I-E synthase (EC 2.4.1.350) (UDP-glycosyltransferase 74-359-2) (UGT74-359-2) (UDP-glycosyltransferase 74AC1) (SgUGT74AC1) (K7NBW3)
Organism: Siraitia grosvenorii (Monk's fruit) (Luo han guo)
Function: Catalyzes the transfer of a glucose moiety to the C-3 hydroxyl of mogrol to form mogroside IE. Besides mogrol, UGT74AC1 also shows activity in vitro with quercetin and naringenin as substrate.
Interaction partners:
Sequence:
MEKGDTHILVFPFPSQGHINPLLQLSKRLIAKGIKVSLVTTLHVSNHLQLQGAYSNSVKIEVISDGSEDRLETDTMRQTLDRFRQKMTKNLEDFLQKAMVSSNPPKFILYDSTMPWVLEVAKEFGLDRAPFYTQSCALNSINYHVLHGQLKLPPETPTISLPSMPLLRPSDLPAYDFDPASTDTIIDLLTSQYSNIQDANLLFCNTFDKLEGEIIQWMETLGRPVKTVGPTVPSAYLDKRVENDKHYGLSLFKPNEDVCLKWLDSKPSGSVLYVSYGSLVEMGEEQLKELALGIKETGKFFLWVVRDTEAEKLPPNFVESVAEKGLVVSWCSQLEVLAHPSVGCFFTHCGWNSTLEALCLGVPVVAFPQWADQVTNAKFLEDVWKVGKRVKRNEQRLASKEEVRSCIWEVMEGERASEFKSNSMEWKKWAKEAVDEGGSSDKNIEEFVAMLKQT
Protein: Protein lin-14 (Abnormal cell lineage protein 14) (Q21446)
Organism: Caenorhabditis elegans
Function: Heterochronic protein which controls the choice of stage specific cell fates. Involved in the temporal progression of vulval fate patterning, possibly by inhibiting lin-12. Acts as a transcription factor involved in the stage-specific repression of insulin/insulin-like growth factor gene ins-33. Plays a role in governing the developmental timining of male tail tip morphogenesis. Plays a role in controlling the timing of seam cell development during the larval stages. Plays a role in promoting survival at high temperatures in larvae. Involved in maintenance of the architecture of the ventral nerve cord, perhaps acting via modulating expression of the immunoglobulin domain gene zig-4.
Subcellular location: Nucleus {ECO:0000269|PubMed:16314527, ECO:0000269|PubMed:19161245, ECO:0000269|PubMed:1916264, ECO:0000269|PubMed:1916265}. Note=May associate with mitotic chromosomes.
Interaction partners:
- Protein lin-28
- Protein lin-41
- Hunchback-like protein
- Zinc finger transcription factor lin-29
- Period protein homolog lin-42
- Nuclear hormone receptor family member daf-12
- LIN-46
- Immunoglobulin domain-containing protein oig-1
- Protein argonaute-1
- Ribonuclease 3
Sequence:
MGKGQPKEPKIEQSVVDLCKRTVAMNLLQCYPTTTVDEMNCEEWGNGTESTQSVAACQGCIELRKEVTDLRQAVNLILPMLPLYPTIGNGFNATGLAAQPTLQHVIQQSLLRKRPVAQTPTVPQPECPGQIRPVLSSPAAALQNVIMLNPWIMGSSLKPASPTLPNGQIPTTIGETSLQGTDDQTVKWIGPSSVDSNGQKTDSSAASAGDNQNIDVIGDGSESPTSSNHSAQEIALMTSQQTFLNALKDSSFLFTNPVPTVETAPPLRVAPPINGTTNGTAKAGGPERKPRKPVNDDIVKIVRNQDLSEENISMFEIPVPKAIASDPTFRPVSEQQIIQQIIQGKKYEEMEVGECMIQLCKKLAEKRVFGPRLMSQTTVAGLNHSNYANLPIKGICYIQHVCRKVLYDKFENEEDFWDKFREAMRKLAARCRRVRHAKKTKHNREEAQAEMLSKRYGEDMPFNLNGAGLIRPKVETVSPEANILNSDQIKSQLESLFAHIPKTESETPLIEIIQQNISLFTHLIRTKVESQSPPLQGPQ
Protein: Serine/threonine-protein kinase PBL13 (EC 2.7.11.1) (PBS1-like protein 13) (Ser/Thr protein kinase ACIK1b) (F4JZW1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in defense responses. Acts as negative regulator of plant immune responses.
Subcellular location: Cell membrane {ECO:0000269|PubMed:26432875}.
Interaction partners:
- Respiratory burst oxidase homolog protein D
- RING/U-box superfamily protein
- Probable E3 ubiquitin-protein ligase ATL45
- protein-synthesizing GTPase
- Probable E3 ubiquitin-protein ligase ATL44
Sequence:
MVLCFQDPDNIYSPKKTKKDDGERVITKQKSFLGLSILDISNPSSTTLSEDLSISLAGSDLHVFTQAELRVITQSFSSSNFLGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLDGLQGHREFMTEVMCLGKLKHPNLVKLIGYCCEEAHRLLVYEFMPRGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLHEAEKPIIYRDFKASNILLDSDYTAKLSDFGLAKDGPQGDDTHVSTRVMGTQGYAAPEYIMTGHLTAKSDVYSFGVVLLELLTGRKSVDIARSSRKETLVEWARPMLNDARKLGRIMDPRLEDQYSETGARKAATLAYQCLRYRPKTRPDISTVVSVLQDIKDYKDDIPIGIFTYTVPTKPRREVKETSLQNFDKPRRETKVTSLQNFDKTRREVKDTSLQNFDKTRREVKETSLQNFDKTRREVKETSLQNFDKPRNVSTTDNHQKFRSPAHTARNHRITLRNGYNSPMRNEAGGERY
Protein: Beaten path Va, isoform A (Beaten path Va, isoform B) (Beaten path Va, isoform C) (IP01704p) (Q9VG24)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Sidestep VI, isoform B
Sequence:
MDYGWLMFLFIALLIDYPIAYALFVTDISVPEIVDFRDNVTLSCSYDMRGHTLNSVKWYKDHEEFFRYSPLTSPIYMTFDVAGLQVLEGKYVCNESSCRLDLSLQGAKSTGLYKCEVSGDAPHFKLADKADNMTVAALPQNDPLIESFNSMYRMEEYLKATCISDFSSLPTRLTWYINGEQPLLGELYPTTDTSLAAHDYVLRRQRLQVQFFLQGQRFFQAGKILELKCVAEIENYPELRREKTLSASLSQYDNFNNQMPLRHANANSGSAQRSILCGRTSLISAFLAAILLIHCLRRPS
Protein: Ataxia cerebellar Cayman type isoform 2 (A0A0S2Z5Y8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTLNFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTHGGYYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLHARPQPEFVLPRSEEKPEVAPVENRSALVSEDQETSMS
Protein: Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST-1) (cHS6ST-1) (EC 2.8.2.-) (Q76KB2)
Organism: Gallus gallus (Chicken)
Function: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate (By similarity). May also play a role in limb development.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Heparan sulfate 2-O-sulfotransferase 1
- Sulfotransferase
- G_PROTEIN_RECEP_F1_2 domain-containing protein
- [heparan sulfate]-glucosamine N-sulfotransferase
- Anosmin-1
- Prokineticin 2
- NMDA receptor synaptonuclear signaling and neuronal migration factor.
- Neuromedin-K receptor
Sequence:
MKRAGRTMVERTSKFLLIVAASVCFMLILYQYVGPGLSLGAPSGRPYAEEPDLFPTPDPHYVKKYYFPVRELERELAFDMKGEDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLGRRESAPNRTPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPSCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNMSFIPENKRAQILLESAKKNLKDMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGGVEVDNDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLERMEQRIKNREERLLHRSNEALPKEETEEQGRLPTEDYMSHIIEKW
Protein: Receptor tyrosine kinase-like orphan receptor 1 (D3ZZ97)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Frizzled-1
- Frizzled-8
- Frizzled-2
- Frizzled-5
- Protein Wnt-5a
- Frizzled-4
- Receptor tyrosine kinase-like orphan receptor 2
- Frizzled-3
- Frizzled-6
- Frizzled-9
Sequence:
MHRPRRRGTRPPPLALLAALLLAARGAAAQETELSVSAELVPTSSWNTSSEIDKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPNIRWFKNDAPVVQEPRRISFRATNYGSRLRIRNLDTTDTGYFQCVATSGKKVVSTTGVLFVKFGPPPTASPGSSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEVLENVLCHTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHSFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILYILVPSVAIPLAIAFLFFFICVCRNNQKSPSPPVQRQPKPVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRFPNYMFPSQGIPPQGQIAGFIGPAIPQNQRFIPINGYPIPPGYAAFPAAHYQPAGPPRVIQHCPPPKSRSPSSASGSTSTGHVASLPSSGSNQEANVPLLPHMSIPNHPGGMGITVFGNKSQKPYKIDSKQPSLLGDSNIHGHTESMISAEV
Protein: E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2) (Q8N7N6)
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin ligase that catalyzes 'Lys63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (By similarity). Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (By similarity). Essential adapter molecule in IL17A-mediated signaling. Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways.
Interaction partners:
- TNF receptor-associated factor 6
- TNF receptor-associated factor 3
- Interleukin-17 receptor A
- Interleukin-17 receptor C
- TNF receptor-associated factor 5
- Interleukin-17 receptor B
- Tumor necrosis factor alpha-induced protein 3
Sequence:
MNRSIPVEVDESEPFPSQLLKPIPEYSPEEELEPPAPNTRNMAPSSLSVLQCPPLKLANHQPVSQQVTCLRAKVLEEGEASFFRRHPELGKDISSCSSGASEPESELGALPPEHRFTLTEKRNRWLGSQLSAASPDTGHESDKSDPSLPNALADSFSGGQEMMPRPRPRPGPHRHRAAPDVPTIDTGYDSQPQDVLGIRQLERPLPLTSSCYLQDLPGPLRSRELPPQFELERYPMNAQLLPPHPSPQAPWNCQYYCPGGPYHHQVPHGHGYPPAAAYQQVLQPALPGQVLPGARARGPRPVQKVILNDSSPQDQEERPAQRDFSFPRLPRDQLYRPPSNGVEAPEESLDLPAELRPHGPQAPSLAAVPRPPSNPLARGTLRTSNLPEELRKVFITYSMDTAMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFISQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL
Protein: Large ribosomal subunit protein uL22 (50S ribosomal protein L22) (P9WHC1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
Interaction partners:
- Small ribosomal subunit protein bS18A
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein bL19
- Large ribosomal subunit protein bL34
- Small ribosomal subunit protein uS8
- Small ribosomal subunit protein bS6
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein uL16
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS4
Sequence:
MTAATKATEYPSAVAKARFVRVSPRKARRVIDLVRGRSVSDALDILRWAPQAASGPVAKVIASAAANAQNNGGLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVESRPAKDQRSAKSSRARRTEASKAASKVGATAPAKKAAAKAPAKKAPASSGVKKTPAKKAPAKKAPAKASETSAAKGGSD
Protein: Arouser, isoform A (Q8IPW1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Peripheral plasma membrane protein CASK
Sequence:
MFKLLSSSFKRRSFRRRSKPVPGLGDTMVNHHSNGGGSAGNSSGSLRGGGAHGGGGGGGDYSGDDRSGGGEERERLESDLHDKPTYLLEHLATFTVNKESGIVYPADGMRRLLQLEKTTGIWSQKMQLCLDYQWVLIMDYETGNIIERFPASLVQEPTAFTSNDAMELYNNILVFIVSGGGGSRSEMHIFQSQSVSAVHLVEDLKQLRSGKMITQQRGATPTQSGGGGASSMAMMMSKTSSSSSHSRVELHQHREQRAERERERDRDRERESHHHMHQRSSMEQYGIRAGVGVSGDDVAHISGETDSEHGGIGGGGATERDETSSTSSEKYERDVAVLNHCFDDIEKFIARLQHAAAASRELERRRRNRKSKKRDPGEGLLTLRTRPPHEKEFVDIFAKFKLSFNLLAKLKAHIHDPNAPELVHFLFTPLALIVEASSDTYYESQLPARVVNPLLTREAINLLINCVTSKETELWRSLGDAWVIPRDQWKDDVGSYHPVFLDGWSPDYLINDELEPPPNSPPAHVSKRRLEVQAGSGLNGRGGGGYDDYDSGNGMNMAMGIEKYTIHHGNDGLRERERERDRERAGAISASDFNARSELSFDSIEGRGGGAAGHGHGHGHGPGAGPTLSAITAGLQNLHTRESRSGNGYGAGAGPGPSSELGGGGRGLPNVSDDQMLESWLEDLQATGAKIVLVTYPRTANNDKELSVMRGEYLEILDDTRKWWKARNMRGQVAHVPHTIVTPFNFGDGDGAQFYGQQQQPPTGPTGPGNKSRSGDNPGMEQRSPDPTDMMRSKHLGKKGEFRYF
Protein: Large ribosomal subunit protein eL33 (60S ribosomal protein L35a) (Q55BN7)
Organism: Dictyostelium discoideum (Social amoeba)
Function: The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
Interaction partners:
- Large ribosomal subunit protein eL18
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL13
- Large ribosomal subunit protein eL19
- Small ribosomal subunit protein eS25
- Large ribosomal subunit protein eL36
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL34
- Small ribosomal subunit protein eS19
Sequence:
MEKIYSKGVVLGYRRSQATQYPNISLIKIEGVVSREDSTFYLGKKVCLVSKVSKSAKNPTGHKISWGKICKTHGSSGVVQARFARNLPPKAMGAPVRVMLYPSNI
Protein: Calcyclin-binding protein (F4I4Q9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- 10 kDa chaperonin, mitochondrial
- Extradiol ring-cleavage dioxygenase
- 17.6 kDa class I heat shock protein 1
- 10 kDa chaperonin 2, chloroplastic
- Aha1 domain-containing protein
Sequence:
MAEEVGLDLEELRQLQNIAKRPRVLNLINSEISNLEKLRDSAVSSNAKPKVPVTVPAPVSSSGKPVSSSALNYVTLGTFSWDQDNDKVKMYISLEGVDEDKVQAEFKPMSLDIKIHDVQGKNYRCAIPKLCKEIMPEKCKVLVKPKRIVITMVKSSRGNWLDIHHKEDKYCLLFVQIKPSLEKEKDPMAGIMGMMKNLYEDGDEEMKKTIAKAWTDARSGKAADPLKGL