wanglab/gogpt-training-data huggingface dataset:
Protein: Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Methylglyoxal synthase) (EC 4.2.3.3) (Triose-phosphate isomerase) (P60174)
Organism: Homo sapiens (Human)
Function: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
Subcellular location: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU10127}.
Interaction partners:
- Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
- Glyceraldehyde-3-phosphate dehydrogenase
- Phosphoglycerate kinase 1
- Glucose-6-phosphate isomerase
- Alpha-enolase
- Phosphoglycerate kinase 2
- Fructose-bisphosphate aldolase A
- Transaldolase
- Triokinase/FMN cyclase)
- Fructose-bisphosphate aldolase C
Sequence:
MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
Protein: UPF3 regulator of nonsense transcripts homolog A (Yeast) (Q3ULJ3)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Regulator of nonsense transcripts 2
- Regulator of nonsense transcripts 1
- Protein mago nashi homolog
- Protein mago nashi homolog 2
- Nonsense-mediated mRNA decay factor SMG5
- Serine/threonine-protein kinase SMG1
- Telomerase-binding protein EST1A
- Nonsense-mediated mRNA decay factor SMG7
- Eukaryotic initiation factor 4A-III
- Protein CASC3
Sequence:
MRSEEGAGGLGAALAARGPSWREKLSSSETHCRRESPRKESAAPPAPTLSESGAGKPREEKRTALSKVVLRRLPPGLTKEQLEEQLRPLPAHDYFEVVAADLSLYPHVYSRAYINFRNPDDILLFRDRFDGYIFIGNKGLEYPAVVEFAPFQKIAKKKLKKKDAKTGSIEDDPEYKQFLESYSLEEEKTSASPETLLGEIEAKTRELLARRTTPLLEYIKNRKLEKQRLREEKREERRRRELEKKRLREEEKRKRREEDRCKRKEAERHKRAEKDVRIKLLKKLETGEEVATEKPKERGEAVGAGDEKQEDRLVASQPETAGERLQDTSDKEPRDKRSREKDPETSRCHPDTCRKHSSHSEFARFSRRNEDEAKWGKGFAQDRGKKGQDGSVPMDVAERSGKEHKEYDSLGPRKDRLGHKAQ
Protein: AT5G66420 protein (TIM-barrel signal transduction protein) (Q9FJZ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKGETYRVFCVGTADTKLDELRFLAGSVRSNIGAFSKNSSSKVEVVIVDVSAGADQKQIDNVADFAFVTREEVLSCYIGSNQEEKPVKLPDDRGEAVGVMSKCLENFLRQAFEDNSLAGAIGLGGSGGTSLISSAFRSLPIGIPKVIVSTVASGQTEPYVGTSDLVLIPSLVDVCGINSVSRVVFSNAGASFAGMVVGRLELFRSSPSDNGKCTVGITMFGVTTPCVNAVQEILTREGYETLVFHATGVGGRAMESLVKEGFIQGVMDITTTEVADHLVGGVMACDSSRFDITIEKGIPLVLSVGALDMVNFGGKDTIPSHFQTRKIHVHNEQVSLIRTTAEENKKFARFIADKLNKSTSKVRVCIPEKGLSALDAPGKPFCDPEATGALINELQGLIQTNDDRQVNIYSHHINDPEFAEALVASFLEICPKTYAQIKPSETTSTKPSTGEHDDGHVRSRLERIPYSPKEFPNAKPETLERTQAILGRLRDQIEKGIPIIGGGAGTGISAKFEEAGGIDLIVIYNSGRFRMAGRGSLAGLLPFADANAVVLEMANEVLPVVKAVPVLAGVCATDPFRRMDYFLKQLESIGFVGVQNFPTVGLFDGNFRQNLEETGMGYGLEVKMISEAHKMGLLTTPYAFNPKEGEEMAKAGADIIVAHMGLTTSGNIGAKTAVSVEESVVRVQAIADAARRFNPDIIVLCHGGPISGPEEAEFVLKRTQGCVHGFYGASSMERLPVEQAITNTVQKYKSISIK
Protein: Dioscorin dioA3 (EC 1.6.5.4) (EC 4.2.1.1) (Dj-dio5) (Dj-dioA3) (Tuber storage protein dioA3) (A7MAQ2)
Organism: Dioscorea japonica (Japanese yam)
Function: Storage protein of tuber. Involved in protection against oxidative stress (Probable). Has carbonate dehydratase, trypsin inhibitor, dehydroascorbate (DHA) reductase and monodehydroascorbate (MDA) reductase activities. Catalyzes the reactions of carbonate dehydratase and DHA reductase independently of zinc and glutathione (GSH). The coupled reaction is capable of recycling a plant antioxidant ascorbate using ubiquitous compounds H(2)O and CO(2). Exhibits antioxidant activity. Able to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. Exhibits immunomodulatory activity. Activates Toll-like receptor 4 signaling pathways by up-regulating the gene expression of pro-inflammatory cytokines, such as tumor necrosis factor alpha, interleukin-1 beta and interleukin-6, and chemokines RANTES and MCP-1, in mouse RAW 264.7 macrophages. Stimulates the phagocytosis of E.coli by the LPS-treated mouse macrophages.
Interaction partners:
Sequence:
MSSSTLLHLLLLSSLLFSCLSCLTNVEDEFSYIEGNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNYRAVDARLRNSGHDVLVDFKGNAGSLSINRVEYQLKRIHFHSPSEHEMNGERFDLEAQLVHESQDQKRAVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEINAGVVDPNQLQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAVNENAINNARPLQPTNFRSVFYFEQLKSKLGVI
Protein: Neurexin-3-beta (I2HAJ6)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Neuroligin-1
- Protein lin-2
- Neuroligin-like protein glit-1
- Protein shank
- Rab-3-interacting molecule unc-10
- Rho GTPase-activating protein syd-1
Sequence:
MRQKFDDTGQYLTIWLVFTVSLFSVVDSIILTGAPDSYARYPKWAHSFENSLSMELKTRQSDGMLLYTDDGGTHGNFYSLTIVEGHIQLDFRLGDNSNEFGQRRPVNTIRIEEVRIDDDKWHTLTIFQSWENVKLELDYTLVFKILNQRSFVFGNILKNSDVFIGGLPPNMHMLPVMSSPLRRYARHLAVNVRNLMYRQYPQGVTSPQLLESVGTRTNEDDHCKSKSMSSREQFVCLNDGECYSSNDGPHCDCQFSDHDGRNCEIEKNDGELTFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKSYLHVMLQDGAIIASSKFDGSDARIIRMFNSFPSQRYDDDSWHTIILERSLQMHSEEMVAIHMTLIVDGRRDEIRQYAPELDWISNSFGFLGSIPKHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHGVMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIIDDPIFIGNVPNNSLVYPSSVWSIALQKGYTGCIKNIRMNGVSTKIGQEFEASNSTGIELGCSLSNELDICEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVNGEESKVHVLAHTKVSQVEHIKIRFRTTSSRGVLFDTGANGKNDKITVFLNDSQLNLFLQDSSTNNTFSWGKSLSDNHWHELQVRRLGQKLLLYLDGFWSHSIYLQNPISVEIDEVGAAFSVHSSAPPPRDEHFKGFLSKLVFNGNDYLAKTKMNSAQLSKSSSRESKGQRNVKTRIASISFTNSTGYVAFSSDKISGLTGSFRVQFKFQTLMRSALLFFTLPKHDYDQSFRLQMLNGRLKYTYRTSGQEFHTTSPKLPHRQHLSDMRWHNVLIYQDEKTHDHVLLVDNSSTTLIIDKIKKVESKMSGKLYFGSNPLGVSRPSNGFRGCISTLRINENALDLYEDADSRMKVNRGCSGPIARCIEDACANHGRCIQLWSSIRCDCSLTAHSGDRCQNPSTTVRFDGSPSAIFYEYAPNERPTTSKDYFVFSFRTTQPNGVLISIECAADQDYFTIFLNKGYLNAHYNLGNRDHTTSYHTRILNDGFPHVIKISRTEANMTIQVDKLPSLRYRPKRASDLVLLNMQTRISIGAAFNTRHLDQKRLLRHRRNTEIFDSYQGEISGVNVNGLMILDLYENGSNRIHTIGAPQTTAVSEQVSSESEEDDELAEMMMAHSIDENPNEALIESLAPSCLSLEEQQSCFIDTDDSTGFFSPVLPTVANFPTTRQTEPETTRRPLSPSKMTPSLPSPTTTTLPVFFLSQITDGDESEDEFDGSGDDLFGGDGVGITAATQPSVKRTTSISVVTKVLTTTSEPSSTHRSTVLPRPYASVKEAAEQNPDYLGASIWNQVDTLPEPMVTGPAWRTNKSLTTTATTEASSTKSNRKTTTTTTTSATTTIRIQQRPNYDIDNEVTALITSSLAPQKTRPKSTPHFTVYPVRPTTPMGDTITTTMQAATVTDFPRTPLIMCSSLAVIIAIAAVVFFVFKCRQNPPNSEHYTMAMKSQSGYTAIAPELSPPMNHDRSNDSCTQPLLAKPHINGNGYEPLKGAVIANGNGATATMMRNGNGNGVAKKKDFKEWYV
Protein: Interferon-induced GTP-binding protein Mx1 (Myxoma resistance protein 1) (Myxovirus resistance protein 1) (K7GKN2)
Organism: Sus scrofa (Pig)
Subcellular location: Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004397}.
Interaction partners:
Sequence:
MVYSNCESKEPDSVSASNHLLLNGNDELVEKSHKTGPENNLYSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEEDEWKGKVSYRDSEIELSDASQVEKEVSAAQIAIAGEGVGISHELISLEVSSPHVPDLTLIDLPGITRVAVGNQPYDIEYQIKSLIKKYICKQETINLVVVPCNVDIATTEALRMAQEVDPEGDRTIGILTKPDLVDKGTEDKIVDVARNLVFHLKKGYMIVKCRGQQDIQDQLSLAKALQKEQAFFENHEHFRDLLEEGRATIPCLAERLTSELIMHICKTLPLLENQIKESHQKITEELQKYGSDIPEDESGKMFFLIDKIDAFNSDITALIQGEELVVEYECRLFTKMRNEFCKWSAVVEKNFKNGYDAICKQIQFVNYKTFETIIKKQVSVLEEPAVDMLHTVTDLVRLAFTDVSETNFNEFFNLHRTAKSKIEDIKLEQEKEAETSIRLHFQMEQIVYCQDQVYRGALQKVREKEAEEEKNRKSNQYFLSSPAPSSDPSIAEIFQHLIAYHQEVGKRISSHIPLIIQFFILRTFGQQLQKSMLQLLQNKDQYDWLLRERSDTSDKRKFLKERLMRLTQARRRPAKFPG
Protein: LD46502p (Q95TJ8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MIKMETPSEFTEKQPPTHDHQPRLNEVAQKFLADLDEERQRLSADFPLCALLIDEAVDRVYCTGRIPGKEFYADVYKQKPMKITQKVFVPVKQYPKFNFTGKILGPKGNSLRRLQEETQCKIAIKGRSSIRDRNKEEQLRSTGDPRYAHLQKDLFLEVSTVATPAECYARIAYALAEIRKYLIPDKNDEVSHEQLRELMEMDPESAKNIHGPNLEAYRSVFDKKFGGNSNGAPKYINLIKRAAENPPEVDDVEEVAYEYEHRMPPKRPPTGYEYSKPRPSIIPTNAAAYKRPYPTDMKRMREPPIKSYKPNPYTILKKYK
Protein: Importin alpha re-exporter (Chromosome segregation protein CSE1) (P33307)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Export receptor for importin alpha (SRP1). Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Importin subunit alpha
- GTP-binding nuclear protein GSP1/CNR1
- Nucleoporin NUP2
- Exportin-1
- Importin subunit beta-1
- Exportin-T
- Protein MSN5
- Ran-specific GTPase-activating protein 1
- Importin subunit beta-2
- Importin subunit beta-3
Sequence:
MSDLETVAKFLAESVIASTAKTSERNLRQLETQDGFGLTLLHVIASTNLPLSTRLAGALFFKNFIKRKWVDENGNHLLPANNVELIKKEIVPLMISLPNNLQVQIGEAISSIADSDFPDRWPTLLSDLASRLSNDDMVTNKGVLTVAHSIFKRWRPLFRSDELFLEIKLVLDVFTAPFLNLLKTVDEQITANENNKASLNILFDVLLVLIKLYYDFNCQDIPEFFEDNIQVGMGIFHKYLSYSNPLLEDPDETEHASVLIKVKSSIQELVQLYTTRYEDVFGPMINEFIQITWNLLTSISNQPKYDILVSKSLSFLTAVTRIPKYFEIFNNESAMNNITEQIILPNVTLREEDVELFEDDPIEYIRRDLEGSDTDTRRRACTDFLKELKEKNEVLVTNIFLAHMKGFVDQYMSDPSKNWKFKDLYIYLFTALAINGNITNAGVSSTNNLLNVVDFFTKEIAPDLTSNNIPHIILRVDAIKYIYTFRNQLTKAQLIELMPILATFLQTDEYVVYTYAAITIEKILTIRESNTSPAFIFHKEDISNSTEILLKNLIALILKHGSSPEKLAENEFLMRSIFRVLQTSEDSIQPLFPQLLAQFIEIVTIMAKNPSNPRFTHYTFESIGAILNYTQRQNLPLLVDSMMPTFLTVFSEDIQEFIPYVFQIIAFVVEQSATIPESIKPLAQPLLAPNVWELKGNIPAVTRLLKSFIKTDSSIFPDLVPVLGIFQRLIASKAYEVHGFDLLEHIMLLIDMNRLRPYIKQIAVLLLQRLQNSKTERYVKKLTVFFGLISNKLGSDFLIHFIDEVQDGLFQQIWGNFIITTLPTIGNLLDRKIALIGVLNMVINGQFFQSKYPTLISSTMNSIIETASSQSIANLKNDYVDLDNLEEISTFGSHFSKLVSISEKPFDPLPEIDVNNGVRLYVAEALNKYNAISGNTFLNTILPQLTQENQVKLNQLLVGN
Protein: Kinetochore protein mis18 (Q9P802)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A. Maintains the deacetylated state of histones specifically in the central core of the centromeres.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:17199038}. Chromosome, centromere {ECO:0000269|PubMed:15369671, ECO:0000269|PubMed:17199038, ECO:0000269|PubMed:26921242}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:15369671}.
Interaction partners:
- CENP-A recruiting complex protein mis19
- Histone acetyltransferase type B subunit 2
- CENP-A recruiting complex protein mis20
- SWI/SNF and RSC complexes subunit ssr4
Sequence:
MSQTETSHSGYIDFKKESQPSVFQCKKCFQIVGDSNAWVISHREYLSFTLSDAVENSVRVEDTFKRSDDGLCVYSELSCTRCNEVIGKVYNSTPIYLDDIRDMYTFSMDKLQAYQLGNKTVNPEGLTRYQVDLEMREDIIKLKSFCLSLYEKFELHDETLRSVKETISSLKKPKIEGKEGKKEKARTYSKRTRK
Protein: C-myc promoter-binding protein (DENN domain-containing protein 4A) (Q7Z401)
Organism: Homo sapiens (Human)
Function: Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Ras-related protein Rab-10
Sequence:
MIEDKGPRVADYFVVAGLTDVSKPLEEEIHFNDACHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLGVTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTFGEPYL
Protein: 26S proteasome regulatory subunit RPN10 (P38886)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Multiubiquitin binding protein.
Interaction partners:
- 26S proteasome regulatory subunit RPN13
- 26S proteasome regulatory subunit 4 homolog
- 26S proteasome regulatory subunit RPN9
- Probable 26S proteasome regulatory subunit p28
- Proteasome subunit beta type-5
- 26S proteasome regulatory subunit 6B homolog
- 26S proteasome regulatory subunit RPN7
- Proteasome subunit alpha type-5
- Polyubiquitin
- Proteasome subunit alpha type-2
Sequence:
MVLEATVLVIDNSEYSRNGDFPRTRFEAQIDSVEFIFQAKRNSNPENTVGLISGAGANPRVLSTFTAEFGKILAGLHDTQIEGKLHMATALQIAQLTLKHRQNKVQHQRIVAFVCSPISDSRDELIRLAKTLKKNNVAVDIINFGEIEQNTELLDEFIAAVNNPQEETSHLLTVTPGPRLLYENIASSPIILEEGSSGMGAFGGSGGDSDANGTFMDFGVDPSMDPELAMALRLSMEEEQQRQERLRQQQQQQDQPEQSEQPEQHQDK
Protein: Protein OXIDATIVE STRESS 3 LIKE 5 (AtO3L5) (KID-containing protein-like 1) (AtKCL1) (Q9SV19)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor (By similarity). Promotes slightly the tolerance to cadmium (Cd) and zinc (Zn) and to oxidizing chemicals (e.g. diamide and tert-butyl hydroperoxide (t-BOOH)).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
Sequence:
MEVLVGSTFRDRSSVTTHDQAVPASLSSRIGLRRCGRSPPPESSSSVGETSENEEDEDDAVSSSQGRWLNSFSSSLEDSLPIKRGLSNHYIGKSKSFGNLMEASNTNDLVKVESPLNKRRRLLIANKLRRRSSLSSFSIYTKINPNSMPLLALQESDNEDHKLNDDDDDDDSSSDDETSKLKEKRMKMTNHRDFMVPQTKSCFSLTSFQDDDDR
Protein: H-2 class I histocompatibility antigen, D-B alpha chain (H-2D(B)) (P01899)
Organism: Mus musculus (Mouse)
Function: Involved in the presentation of foreign antigens to the immune system.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Beta-2-microglobulin
- Killer cell lectin-like receptor 3
- T-cell surface glycoprotein YE1/48
- Killer cell lectin-like receptor 4
- Killer cell lectin-like receptor subfamily A member 9
- Killer cell lectin-like receptor 7
- H-2 class I histocompatibility antigen, K-B alpha chain
- Tapasin
- T-cell surface glycoprotein CD8 alpha chain
- Antigen peptide transporter 1
Sequence:
MGAMAPRTLLLLLAAALAPTQTRAGPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEPPPSTDSYMVIVAVLGVLGAMAIIGAVVAFVMKRRRNTGGKGGDYALAPGSQSSEMSLRDCKA
Protein: Histocompatibility 2, T region locus 10 (Q8WLM9)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MSWVLRAAVVCALLLQLDARSSWIPLGSHSLRYFYTAVSRPGLGEPWFIIVGYVDDMQVLRFSSKEETPRMAPWLEQEEADDWEQQTRIVTIQGQLSERNLMTLVHFYNKSMDDSHTLQWLQGCDVEPDRHLCLWYNQLAYDSEDLPTLSENPSSCTVGNSTVPQISQHLEGHCSDLLQKYLEKGKERLLRSDPPKAHVTRHPRPEGDVTLRCWALGFYPADITLTWQKDGEELTQDMEFVETRPAGDGTFQKWAAVVVPLGKVQSYTCHVDHEGLPEPLTLRWEPAWYQKPWIWIVATVFSILLICLCVARICMKKNAGGRGRRDTQEAGRDSPQDSSKTVVDDEEMGVCFWKIKYCKTCLGHSSGTSVGESLLSP
Protein: SHOCT domain-containing protein (Q55AC0)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
Sequence:
MDYVPKTELEKLNELFSMGFITEWEYNNRKKDLGVDDDNNNNSINNKTTSNDSNDYYNNNNYSSSSYNNNNNNDYYSNNDYNQIIPVIQNDYQNDSTTNNNNYSNNNNDYYNQVIPVLNNDFQTDTTNNSNTYDYYNNYNYENNNNNNSNTYDYSNNNNLNDNYNNNSFYQQEDYSNNQINNSNNSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNENIEKDDDIYVIKIKDPIIVKKNSNLIGNKNIDNEKSNKVKEYPLKVKDSYTIHKDIGNNIVLYFKDKACNYQSDLIAIKDKSKTDILKEIYKFVGLDYEKSISTLLIFKMIINDKRTAKPNEFYNYSPPSETILIPIEFSDPELLKPNHLLIQFGSFPIHRNRWNPTTKFTSTYNFTGTTEYFKGYKGDPVKIDRVKCPYVIDKFKSDFSIPQYGFTKYMGVPSEQITNFYSPSIRPEPCKPIVYHNDNNNSERNATWLKLNFLILFRYLQSRAVNDGRTVTYGEQLPNLVSKDSSIEILEPLKDSINQSKCLICSRSTLSFGNFLCNTHYSKDLMDAFEKCKPYLFLDANNEPIKQLPKDQLESFKENEKKKEKTVFIKDKFAYIDPSNLQSILDKKVKPYTQENNNYNYNSNYDDYY
Protein: Chromatin structure-remodeling complex protein RSC58 (A0A1D8PG45)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RSC chromatin remodeling complex ATPase subunit
- Bromo domain-containing protein
- RFX-type winged-helix domain-containing protein
- Chromatin structure-remodeling complex protein RSC8
- Uncharacterized protein
- Arp9p
- Npl6p
- Chromatin structure-remodeling complex subunit RSC1
- Uncharacterized protein
- Chromatin structure-remodeling complex subunit SFH1
Sequence:
MTKDIENQSSSSSKFESILPDLFTVYEHTNKDVLTNEILPVDFYQENPMKIVSSLQSHTTTDVTSIKNKYKNGQYSTPYQLFHDIKAVASILLNKEENGSLQYKELDFFYKFSTELLLREVGNLIKFNNETGEIKTELETQLDEDFTKIITNYNISNGEVITYISTTEEPEPQSSSVLYQHHQHKEEPTKKTQPLFSSVISKSELDNRASIVPSPYGLAQVVPSIKDSSSENTLETLSPIANRIPSPLDQPTNILHDFFHPTWYTISVPAWLTYTSQTIKPANLNTNQESEDGVGASTKTKLSILKNRDNDYSTKPTNIWGPGNYYRSFAPSRNSSGSIVGNKLKANVWLQHIGMTEIAELKESFVENKNETNPLDNDTVVGKEDAGEGKSSKENGAEPTNGHQASEKTQQPSSRQAINIANIIKWDPTKVEELNYLKEHKQDLVNPQKLQKMISISLLKLNKLRQQRYSRSDVRNPLAPQHEENILYNRVVKLISIAIQLFNVNPGCFSYQFSKNIPVLVSEFSGTLPGIPPTKAIVNNGTTATTKSNRLPNLKGPSAYRKRPTRFA
Protein: Tyrosine-protein phosphatase 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2) (PTPase 2) (P32586)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.
Subcellular location: Cytoplasm.
Interaction partners:
- Mitogen-activated protein kinase sty1
- Protein kinase wis1
- Protein phosphatase 2C homolog 3
- Tyrosine-protein phosphatase 1
- Mitogen-activated protein kinase spm1
- Protein phosphatase 2C homolog 1
- Tyrosine-protein phosphatase pmp1
- MAP kinase kinase kinase wis4
- Mitosis inhibitor protein kinase wee1
- M-phase inducer phosphatase
Sequence:
MLHLLSKDEFNSTLKSFEEQTESVSWIIDLRLHSKYAVSHIKNAINVSLPTALLRRPSFDIGKVFACIKCNVKVSLDEINAIFLYDSSMAGMNRIYDLVQKFRRGGYSKKIYLLSNGFEAFASSHPDAIVSTEMVKESVPYKIDINENCKLDILHLSDPSAVSTPISPDYSFPLRVPINIPPPLCTPSVVSDTFSEFASHAEYPGFSGLTPFSIHSPTASSVRSCQSIYGSPLSPPNSAFQAEMPYFPISPAISCASSCPSTPDEQKNFFIVGNAPQQTPARPSLRSVPSYPSSNNQRRPSASRVRSFSNYVKSSNVVNPSLSQASLEIIPRKSMKRDSNAQNDGTSTMTSKLKPSVGLSNTRDAPKPGGLRRANKPCFNKETKGSIFSKENKGPFTCNPWGAKKVSPPPCEVLADLNTASIFYKFKRLEEMEMTRSLAFNDSKSDWCCLASSRSTSISRKNRYTDIVPYDKTRVRLAVPKGCSDYINASHIDVGNKKYIACQAPKPGTLLDFWEMVWHNSGTNGVIVMLTNLYEAGSEKCSQYWPDNKDHALCLEGGLRISVQKYETFEDLKVNTHLFRLDKPNGPPKYIHHFWVHTWFDKTHPDIESITGIIRCIDKVPNDGPMFVHCSAGVGRTGTFIAVDQILQVPKNILPKTTNLEDSKDFIFNCVNSLRSQRMKMVQNFEQFKFLYDVVDYLNSGVNQASKPLMT
Protein: Zinc finger protein 418 (Q8QZZ2)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVCIQGCVTFEDVAVYFSQEEWELLDESQRLLYLDVMLENFTLITSLAHWSEAEAEDKTCAPQIRTAKEGLPTKKPHPSDICSTVLKDILHLSDLPGQKPHLTEVCTDLLDQKHHRAKNWLKKDVDSLVKNCIFHVAGNPSVCSKIGEKFPAVWNLLQPKAIPKGEKQNQIKCRKAFHSEKNNSKSDKYNKSSSPQHRLHEYPRLCSGKEGFESNSCEQDLNKYSIAPSQTDQTENRPYGCHDCGKWFGQKATLRIHQRRHTGEKPYRCGECGKSFCQSSNLSEHCRVHSGERPFECLECGKAFGCHSSLLRHQRTHTGEWPYECGDCGRLFRQIVSLITHQRTHTTEKPYECGQCEKSFSHKATLTVHQRVHTGEKPYHCEACGKSFSQSANLIKHSKIHTGEKPYKCGECGLCFRQRATLMKHQRTHTSERPYECRECGKFFKQYFYLIEHSRIHTTTEFYECGQCGKSYTQNATLIRHQRVHTGESPYKCKECGKAFEYKSRLNRHQRTHTGERPYECAKCGKFFRESYNLAEHQKIHTKAKPYNCDQCGKCFSRRADLVKHQRVHTGERPYTCGECGKTFSRTTNLVQHRRIHTGERPYECDQCGKSFSQVSTLTRHQLLHTGEKSYKCSK
Protein: Glutathionylspermidine synthetase, putative (Q384E7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAKGSDYDAVAYEPMPREGFDAGDEGPLVGNHDQGFLFDDQADGAHSTQLTYIAPSVKKPVYALGITLLFLLVAVVLTVILQPTFLYGETCVTPFGTIIGVHNGVFAYSNCRRDHISTKKNSIKGEGSMETGMEWQCFEYVKRYWIMRGVPQSVILPTARKSSELWSFTQATFKNGSKVQLERHDNGGPQPLVGDLLVYREQPALLPVGHVAVIVRVGKTHVWVAEQNWFNKQWHPPFHNFSRTIKMHHNAESQTYELEDMAGTTIKGWMRYKT
Protein: von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog) (Q99KC8)
Organism: Mus musculus (Mouse)
Function: May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in may contribute directly to or modify tumorigenesis (By similarity).
Interaction partners:
Sequence:
MEHHCGLITSNKETVPLKNISVTLSINEFVAAVVATLNYENEEKVPLEATFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKAHSEYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGAKVAVTLRYVQELPLETDGALRYLLPAILNPRYQLSEQSANSCLNIQKPTVPLEDLPYTLNMTATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYNEVHSPSVAVEMGMLDMKPDSLMGAPSAMVSFYPDIPEVEASKACGEFVFLMDRSGSMDSPMSTENNSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEKFFPESVKYTQDTMEDAVKRVKALKANLGGTEILTPLCNIYKASSIPGHPLQLFVFTDGEVSDTFSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAVFITGKDRMQTKALGSLKFALQCAVDNISLSWDLPPGLSVKMLSPEQLTIFRGQRLIIYAQLTGLMPQVESTGAVCLKHILQGRSLENRVTFSLQPKANDNFTIHRLAAKSLIQTKDFGSQEASKEEKEDVMNISLQSGVLSSFTAFIAINKELNKPVQGPLAHRVIPRPVMAGSSSMRFYSSFSGGFKGPQPRSLRVPAYDLCSAESANLVLKKSACSAIQKKKTNSSTNKSNLKKEHKAFGENAVVQLISLQKANGSWELDEDLTKILGTKSKDIKAANPAKHEDPSAWSTVLAVVWLHANGTDLKCEWELLERKAVAWLHDHAGSSIPMLVQAANSLLKLSVNPAVFGV