wanglab/gogpt-training-data huggingface dataset:
Protein: Hemoglobin subunit alpha-1/2 (Alpha-1/2-globin) (Hemoglobin alpha-1/2 chain) (P01948)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Involved in oxygen transport from the lung to the various peripheral tissues.
Interaction partners:
Sequence:
MVLSPADKTNIKTAWEKIGSHGGEYGAEAVERMFLGFPTTKTYFPHFDFTHGSEQIKAHGKKVSEALTKAVGHLDDLPGALSTLSDLHAHKLRVDPVNFKLLSHCLLVTLANHHPSEFTPAVHASLDKFLANVSTVLTSKYR
Protein: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (A0A0R4IVJ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- EGF domain-specific O-linked N-acetylglucosamine transferase
- O-linked N-acetylglucosamine
Sequence:
MITGQLRKTFSLFAYKEQTFRRKRLLPPVTSAISLETEKPCFAQNTAMDPVKSEGEMASSVGNAADSTEPTKHVLSFQGLAELAHREYQSGDFEAAEHHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDMSFQFSTLATKQNPMLAEAYSNLGNVHKERGQLQEAIERYRQALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALHCNPDLYCVRSDLGNLLKALGRLEEAKRCYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDASFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRHAIELQPHFPDAYCNLANAMKEKCNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPDFAAAHSNLASVLQQQGKLQEALMHYEEAIRISPTFADAYSNMGNTLKEMQDIQGALRCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINALHKTAYEHPKDLKASSGRLRVGYISSDFGNHPTSHLMQSIPGMHNSEKFEVFCYALSPDDGTNFRVKVMAEAHHFIDLSHIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQVMWLGYPGTSGAPFMDYIVGDKVTSPIEVAKQYSETLVYMPNSFFIGDHANMFPHLKKKAIVDIKSNGHIFDNRIVLNGIDLKVFLESLPDVKVLKMECDDQVAADSNGALSMPIIPMNTAAEAIINMINQGQIQVTINGFTVSNGLATTQINNKAATGEEVLKTIVVTTRSQYGLPDDSIVYCNFNQLYKIDPPTLQMWANILKRVPNSVIWLLRFPAVGEPNIQQYAQNLGLPASRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASCVAASQLTCLGCPELIARSRQEYEDIAVKLGTDMEFLKKVRARVWKQRICSPLFNTKQYTVNLEKLYLQMWENHASGGKPDHLVKMQSLETSEST
Protein: Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein (F4JMQ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MVAFGKKLKERSIQEWQGYYINYKLMKKKVKQYSRQLEGGNLERRHVLKDFSRMLDNQIEKIALFMLEQQGLLASRLQTLRGSHDALQEQPDISHMSYLKEEYRAVGQDLLKLLFFVEMNAIGIRKILKKFDKRFGYRFTNYYVKTRANHPYSELQQVFRHVGLGAVVGAVSRNLHELQNNQGSYLSIYDQPVLPLQDPVVDSIRAAVDRLTRSTNFLHFMAQHALIMQEELPSPQDEEGEEEDGRYHFMSLLLNLVNTFLYMVNTYIIVPTADDYSMSLGAAATVCGVVIGAMAVAQLFSSVYFSAWSNRSYFKPLIFSSIVLFIGNLLYALAFDFNSIAVLLIGRLFCGLGSARAVNRRYISDCVPLKIRMQASAGFVSASALGMACGPALAGLLQIRFKIYKLTFNQDTLPGWVMAVAWLIYLVWLAISFREPAREPEEIPKTSEESNHSEAVQDVNLEKGMKQPLLLTSEEIEEQGEDECDGSEEASEDSRTPANSILAAYRLLTPSVKVQLLIYFMLKYAMEILLSESSVITTYYFGWSTSSVAIFLFCLGLTVLPVNLVVGSYISNMFEDRQILLVSEIMVCVGILLSFHVVVPYTVPQYVCSGLIMFVSAEVLEGVNLSLLSRVMSSRLSRGTYNGGLLSTEAGTIARVIADATITVAGFFGRNMLLNVTLLPSLVICVLSIVATCFTYNSLY
Protein: Cardiac-enriched FHL2-interacting protein (D3Z1D3)
Organism: Mus musculus (Mouse)
Function: Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.
Subcellular location: Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:28717008}.
Interaction partners:
- Mitochondrial disaggregase
Sequence:
MMQGNKKCTDGFSDTSSIGSVLDEADREVSNLTDRAFRSLCISEDTSFHDSDLALSPDVTSQVSGTFHQETVGHANRKSGIWSQLPSQGTEHSGWAATFQQQPKYVQGEEKYPKTSPLPTPVQRRLEVPISGLRSSSKPISKVSSLIRSFDRTETQSCDSRPPPSKPPALKNPPKFAHPPESGVNFCFDSAFLTVRRVPAEVSNTHQGSHQSGRAPGEQESPKNPEIASHSSDSLLRTPDHVAGSFEPRYPSPPLKPATAEPGRGKEWIPRRTFLHSENSAFESWDTHQPKLRERKDIAETTPESKAPKHYEDMPLLKEPYPAESKGSPYQARANCAQEENRSPSGSQSTSGAWGARDPGSQLFPVEGNASQIDPQVKRSKAPWRKPKTGKGGTDGPPDALEDKKQPNRRGLPLYSKLNPQGQLPENGVLDMPEESNDHYNPPFNISKLLTPIISTKHVLETSDTQPVEISPSPPGQLNGYQEKESSEAQSRDSYKSKAPSLLFNLKDVRKRVKSTYSPLPLLKGFDEKTRGKLDSKQEPLSNGVTLPDGLEENPPTELLPDNVPGVLHSSTQKDPAINSRESFAVSHPTFSSPSASSQTHFCVNGEAAESNSNEKEEANGESELDPSKGGGHPDCRENLPRKHLSLKLFNRESEMGPAMAEMKPHQLENGLSRSVSQETETERETGFQSLPLNQKFSPGPLSPEEEDVFYSDSQSDFTPCRQTKAKFSTSSSDQSFASFEDQQKVCFTEGPQEDRKSHVSAGDKQRDETAVEKEESQQCASRNEHRGVDEQRQEEIQRKAQGVSGGRPRKASAEDLSARGSWMGADKDTAHTHAKDPTPLPASTNKHRLFPIKDNTLRATPVIKPIILPLLRTVSSEDSLSSGHQENELPKQLWGEDAGGLSASESQEMPNTPLSNNDVPGTQHRCMVCEDVQEDPVHTAAQDETSQQTRKGSFSFLPPVEEENRMKPSPDTAGEGLAQEKSKSADLGKLGVPQRIPTIALLPDDLEDSPPSLPQHTYWEEQGFKGHFLSAPRAGPSGRRLVPSEAETSPNPSSLGESSTCSPAASSIWEEASQAAGEHWQRQEPPGPNPWASPGPTGLTRREDMTHGLTWEAEGSDPSDFRALSPRGILLADAAEKPEPPALLEKAAGKPPAVPPKTEKALRRAKKLASKRRKSDQLLEKHTEAWEGKSFTEDTQGTERRPVSPGKGPRPRFPAIRSLPPPTHRHSVSCGWEPTGRRPWGPQSLTPLPPYPATQKVLQDPQSGQYFVFDVPLQVKIKTFYDPETGKYVKVSVPSSEEASSEPPLQDALAAPYLLYPGFRPVPVTSVMPLRCSSQLAAPTFLRQGSGHRPQSSQGSRLQPPPERLGESTQHASGQCPRGPSHSPEKESAEAPRLSIISTDDLEDFATEGVS
Protein: GTP-binding protein rhoA (Rho1 protein homolog) (Q9C3Y4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Has a role in cell polarity, primary and secondary germ tube emergence and cell wall deposition.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Rho GTPase activator Rga
- Uncharacterized protein
- SH3 domain protein
- Uncharacterized protein
- Rho-GAP domain-containing protein
- Cytokinesis protein sepA
- protein kinase C
- Uncharacterized protein
- Rho GDP-dissociation inhibitor
- Actin, gamma
Sequence:
MAEIRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAVDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRHDPKTIEELNKTSQKPVTPEQGEEVRKKIGAYKYLECSARTNEGVREVFEAATRAALLTKTHKSKKKCSIL
Protein: Protein GAMETE EXPRESSED 1 (Q681K7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has a dual function during gametophyte development and early embryogenesis. Required for correct pollen maturation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16055690}; Multi-pass membrane protein {ECO:0000269|PubMed:16055690}.
Interaction partners:
- Protein GAMETE EXPRESSED 2
- Protein HAPLESS 2
- Embryo defective 1381
- Ankyrin repeat protein
- Nuclear pore complex protein GP210
- Protein GAMETE EXPRESSED 3
- Meiotic nuclear division protein 1 homolog
- Protein SHOOT GRAVITROPISM 6
- Probable sphingolipid transporter spinster homolog 1
- At1g09815
Sequence:
MDRFSRKCLLFLLLIILLDSPLTCHSWGWFSSSSSSAEDPYSSSFSRSRKSNPDFSMEVFSDQKAVQVLENKLVGLTSCWQNAYSYLLAGCKETIATEEKRKRFAWYLSDCFIKDSGRPAFPTCKDESVMMSCLKKLDDHEHKIYLDFLLETNTICQQLQSNAFKNEIERLVNELKNTAQYTEDKLDILESKSDALIQTSSMIHDSLGSLDVRVQNVASVTNTLETSVSGLSQQTVEISQEQKNIAESQLALRDGQVKMKETLKDGMDMFLDAYTNIQEGVDKLKSDTEQIEVEISVLGNNLSTKMIDLQSTTDDIGTKTRSSLDKQQKLLDGQTVALDGIQFLTRFQSEALQESRNTLQRLKEFSQEQQEDLAKRQEKLQEVHDHLFENSKSMLEAQVAFEAKQANMFVALDKLFALHNAMLLESRVIKAFVIYFLSIFVIYMFTSTKQTYIIRPRLYIGLCVTLALEVASLRYVNDTERQAWMINLIRSLFALLASAQLLHAALSYRDYEVLNHQILLRLVDKVNDMQSKKELSYDEDTESEVDWTSWVDTDLTDDDDNLADPDYKIPLLIKDNPVTTSSLTRRLYNFRPR
Protein: Phenoloxidase subunit 2 (EC 1.14.18.1) (proPO-p2) (Q25519)
Organism: Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
Function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone. Binds to the surface of hemocytes and is involved in hemocyte melanization.
Subcellular location: Secreted {ECO:0000269|PubMed:9474780}.
Interaction partners:
Sequence:
MADIFDSFELLYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRKIILKNLDKIPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYARINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIPRTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELFFYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYARFTHLNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTVGGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSATNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA
Protein: Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.19) (Cis-benzene glycol dehydrogenase) (P08088)
Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
Interaction partners:
Sequence:
MRLEGEVALVTGGGAGLGRAIVDRYVAEGARVAVLDKSAAGLEALRKLHGDAIVGVEGDVRSLDSHREAVARCVEAFGKLDCLVGNAGVWDYLTQLVDIPDDLISEAFEEMFEVNVKGYILAAKAALPALYQSKGSAIFTVSNAGFYPGGGGVLYTAGKHAVIGLIKQLAHEWGPRIRVNGIAPGGILGSDLRGLKSLDLQDKSISTFPLDDMLKSVLPTGRAATAEEYAGAYVFFATRGDTVPLTGSVLNFDGGMGVRGLFEASLGAQLDKHFG
Protein: Myosin regulatory light chain 2 (P19626)
Organism: Caenorhabditis elegans
Interaction partners:
- Myosin, essential light chain
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- Troponin I 2
- Troponin T
- Tropomyosin isoforms a/b/d/f
- Myosin-4
- Troponin T
- Troponin I 1
- Paramyosin
Sequence:
MSKAAKKKSSKKRSGSEAAQFDQKTIQEFKEAFGIMDQNKDGIIDKSDLKDLYASMGQIAPDSQIDAMIKEASGPINFTVFLTLFGERLTGTDPEATIVGAFAMFDKKDCGKIKEDDLIKILQNKRGEPLDEDEVKAMYKGKPPIEGGEVDYKAFAHLITTGAQDELASA
Protein: Uncharacterized protein YJR056C (P47115)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Protein HIT1
- Uncharacterized protein YJL028W
- Uncharacterized protein YJL027C
- Mitochondrial membrane protein FMP33
- Putative uncharacterized protein YJL009W
- VPS10 homolog 2
Sequence:
MEQMHSLESSLPPEQPPTKQAIESLNLELSQEFKLAANAVTRLYRVANEKNSLTKHQGYLTCLDDILCALDSNVTADELRAWCYKRRNDILSNSQDKSLNPVKERERKLNKFSENQHRENEAHKEPFEKDSAVKYNFSFNESNGDLSNINENIAPKFRLSMPPLSVEHPPRNASRIKSWKARTINHGRGDTRNLNDITGLGHERERDRENTHYEKKPKLDSDSEVDIRSFRQDMDL
Protein: Probable cellulase Cel12b (EC 3.2.1.-) (O53438)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable cellulase CelA2a
- Probable beta-glucosidase BglS
- Glucanase
Sequence:
MGTNLPTEVGQILSAPTSIDYNYPTTGVWDASYDICLDSTPKTTGVNQQEIMIWFNHQGSIQPVGSPVGNTTIEGKNFVVWDGSNGMNNAMAYVATEPIEVWSFDVMSFVDHTATMEPITDSWYLTSIRAGLEPWSDGVGLGVDSFSAKVN
Protein: Cis-prenyltransferase 7, chloroplastic (SlCPT7) (EC 2.5.1.-) (K4CA50)
Organism: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Function: Uses geranylgeranyl diphosphate to catalyze the cis-prenyl chain elongation and produce polyprenyl diphosphate with a chain of 35 carbons.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:23134568}. Note=Localizes in punctuate patterns inside the chloroplasts. {ECO:0000269|PubMed:23134568}.
Interaction partners:
Sequence:
MLSLGFSLPPPSDNKLIITNNNQYNYRTNLANVCSNNNVNAVGDQLVTLPEGLKHVAVIMDGHRRWAKNKGLTVKQGHRAGGEKIQVLTRLCSQWGVKVLTIFAFSTENWVRLEEEVDFLMKLFLELIGSQEILDEWTRDGRRVSFIGDKSIFSKSLQEALAVMEERTKFNSGLHVIIAINYSGRQDILQATKSIAIKVKNGDLTVKDIDQSLFEQELDTHCTEFSEPDLLIRTSGEKRVSNFMLWQLAYTELYFANKLFPDMEEADFIEALTSFKSRQRRYGGKKI
Protein: CRM-domain containing factor CFM9, mitochondrial (Protein CRM FAMILY MEMBER 9) (Q9LT57)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the splicing of group II introns in mitochondria. Required for the splicing of mitochondrial introns found in nad1, nad2, nad4, nad5, nad7, rps3 and cox2 genes. Splicing of mitochondrial introns is crucial for mitochondrial biogenesis and function, plant growth and development, and plant response to abiotic stresses.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:31359042}.
Interaction partners:
- At4g39040
- CRS2-associated factor 2, chloroplastic
- U11/U12 small nuclear ribonucleoprotein 31 kDa protein
Sequence:
MNQVFKGWSRGMSTSRGRSMRSKVESRMRKESGKTLREIRRAKKLKKKLMTDEERLIYNLKRAKKKVALLLQKLKKYDLPELPSPVHDPELFTSEQVQAFKKIGFKNKNYVPVGVRGVFGGVVQNMHMHWKFHETVQVCCDNFPKEKIKEMASMIARLSGGVVINIHNVKTIIMFRGRNYRQPKNLIPVNTLTKRKALFKARFEQALESQKLNIKKTEQQLRRMGVNPEDPVAMASIHRVASTFFNAIDKKEGTPYVFHGDKQSERGTSVDNREESEPGDEDSDQEELDRFIAEIEEAADKEWEEEEAAEQEESGRIRYWNREEFAGRSRTPELRSYGDASHGFRRNDRDTHSQRRPNDSDDDDDDGELDSEDDEIPKRFDRARSSNTNTRRPREDFKRRSPDPRPRPRAQVRSDDDVLSDLDNTMWDSEDEEDAPPANYISSSDDDEDENRTVSASSSKQSRFRNNSSRDGINNSKSKSGKQRDEDWDSD
Protein: Receptor-like protein kinase BRI1-like 3 (EC 2.7.10.1) (EC 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) (Q9LJF3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Binds brassinolide. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development. May be involved in cell growth and vascular differentiation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15486337}; Single-pass type I membrane protein {ECO:0000269|PubMed:15486337}.
Interaction partners:
- BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1
- Protein BRASSINAZOLE-RESISTANT 2
- Protein BRASSINAZOLE-RESISTANT 1
- Serine/threonine-protein phosphatase BSU1
- BRI1 kinase inhibitor 1
- Steroid
- Serine carboxypeptidase 24
Sequence:
MKQQWQFLILCLLVLFLTVDSRGRRLLSDDVNDTALLTAFKQTSIKSDPTNFLGNWRYGSGRDPCTWRGVSCSSDGRVIGLDLRNGGLTGTLNLNNLTALSNLRSLYLQGNNFSSGDSSSSSGCSLEVLDLSSNSLTDSSIVDYVFSTCLNLVSVNFSHNKLAGKLKSSPSASNKRITTVDLSNNRFSDEIPETFIADFPNSLKHLDLSGNNVTGDFSRLSFGLCENLTVFSLSQNSISGDRFPVSLSNCKLLETLNLSRNSLIGKIPGDDYWGNFQNLRQLSLAHNLYSGEIPPELSLLCRTLEVLDLSGNSLTGQLPQSFTSCGSLQSLNLGNNKLSGDFLSTVVSKLSRITNLYLPFNNISGSVPISLTNCSNLRVLDLSSNEFTGEVPSGFCSLQSSSVLEKLLIANNYLSGTVPVELGKCKSLKTIDLSFNALTGLIPKEIWTLPKLSDLVMWANNLTGGIPESICVDGGNLETLILNNNLLTGSLPESISKCTNMLWISLSSNLLTGEIPVGIGKLEKLAILQLGNNSLTGNIPSELGNCKNLIWLDLNSNNLTGNLPGELASQAGLVMPGSVSGKQFAFVRNEGGTDCRGAGGLVEFEGIRAERLEHFPMVHSCPKTRIYSGMTMYMFSSNGSMIYLDLSYNAVSGSIPLGYGAMGYLQVLNLGHNLLTGTIPDSFGGLKAIGVLDLSHNDLQGFLPGSLGGLSFLSDLDVSNNNLTGPIPFGGQLTTFPLTRYANNSGLCGVPLPPCSSGSRPTRSHAHPKKQSIATGMSAGIVFSFMCIVMLIMALYRARKVQKKEKQREKYIESLPTSGSSSWKLSSVHEPLSINVATFEKPLRKLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKLIQVTGQGDREFMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQVDTENDSLDEFLLKETPLVEESRDKEP
Protein: Activated in Blocked Unfolded protein response (Q20002)
Organism: Caenorhabditis elegans
Interaction partners:
- Activated in Blocked Unfolded protein response
- Activated in Blocked Unfolded protein response
- Activated in Blocked Unfolded protein response
- Activated in Blocked Unfolded protein response
- Nematode Specific Peptide family, group B
- Zinc metalloproteinase nas-30
- Activated in Blocked Unfolded protein response
- Chitin-binding type-2 domain-containing protein
- SKN-1 Dependent Zygotic transcript
Sequence:
MFRSAFSIFAIVALALSAPTLREKRQACSCAPVQQQPSCCQQSTINVQVQYTQVQQAPAQDPCACQPQQQQPACNCAPVQQDPCACQPQQQQPACNCAPVQQDPCACQQQQPSCDCAPVQQQPACDCQPQQQPACDCAPVAQQPACDCQQNPSCVTCIQIEIRQQQAQQPACDCAPVQQNPCCQQAQPACDCAPVQQQPSCDCAPVQQNPCCQQAQPACDCAPVQQQPACDCAPVQQNPCCQQQAQSTCDCAPVQQNPCCQQAQPACDCAPVVQQNPCACQQAQPSCDCAQQAQPTFQVQVQQAQPINQCVPACQPACQSSCTASYTNQQSQHSSATTSCDANQCVCQRGYVKCAEQTCCLRYRYTNRKAKRSIA
Protein: Piriformospora indica-insensitive protein 2 (Q5PP26)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for growth promotion and enhanced seed production mediated by the endophytic fungus Piriformospora indica.
Subcellular location: Cell membrane {ECO:0000305|PubMed:17397506}; Peripheral membrane protein {ECO:0000305|PubMed:17397506}; Extracellular side {ECO:0000305|PubMed:17397506}.
Interaction partners:
- Protein NOI4
- F21D18.12
- MADS-box transcription factor family protein
- MADS-box transcription factor family protein
- MADS-box protein AGL35
- At5g27810
- At5g55690
- MADS-box transcription factor family protein
Sequence:
MLWQTFFSSLLLLSLLFGCNGDESLPEVTDSEEAPMDKREREALYSAIQGFVGDSWNGSALYPDPCGWTPIQGVSCDIYNDLWYVTDLSLGLIYENSLPCSSSLQIRPELFELKHLRSLSFFNCFISPMVIAKEELWTNFASNLESLEFRSNPGLIGELPETIGNLTKLKSLVVLENGFSGELPASICNLKRLKRLVFAGNSFAGMIPNCFKGLKELLILDLSRNSFSGTLPTSFGDLVSLLKLDLSNNLLEGNLPQELGFLKNLTLLDLRNNRFSGGLSKNIENIQSLTELVLSNNPMGEEDMVGTNWGKMSNLVVLDLSKMGLRGEIPTSLTNLKRLRFLGLNNNNLTGFVPSKKLEALPCLGALYINGNNLTGELRFSTKFYEKMGRRFKASKNPNLCQPLEMVMSESHKHLSPLGVKPCT
Protein: Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45) (P22515)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. The RSP5-UBA1-UBC5 ubiquitin ligase complex ubiquitinates RPO21 forming 'Lys-63'-linked polyubiquitin chains.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Polyubiquitin
- Ubiquitin-conjugating enzyme E2-34 kDa
- Ubiquitin-conjugating enzyme E2 4
- Ubiquitin-ribosomal protein eS31 fusion protein
- Ubiquitin-conjugating enzyme E2 13
- Ubiquitin-conjugating enzyme E2 1
- Ubiquitin-conjugating enzyme E2 2
- Ubiquitin-ribosomal protein eL40A fusion protein
- NEDD8-conjugating enzyme UBC12
- Ubiquitin-conjugating enzyme E2-16 kDa
Sequence:
MSSNNSGLSAAGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAANGSDEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL
Protein: protein-tyrosine-phosphatase (EC 3.1.3.48) (F1LXJ9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MGSLGALALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDADSPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKAPMGSAQVTPGTPLCLLTTGASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRRKLAKKQKETQSGAQREMGPVASTDKPTTKLSTNRNDEGFSSSSQDVNGFTDGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQLCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKAVRRLEKWQEEYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF
Protein: Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha-neuraminidase 2) (Q9Y3R4)
Organism: Homo sapiens (Human)
Function: Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Recognizes sialyl linkage positions of the glycan moiety as well as the supramolecular organization of the sialoglycoconjugate. Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles. Hydrolyzes monomeric GM1 ganglioside, but has no activity toward the miscellar form. Has lower sialidase activity for glycoproteins such as fetuin and TF/transferrin that carry a mixture of alpha-(2->3) and alpha-(2->6)-sialyl linkages. Cleaves milk oligosaccharide alpha-(2->3)-sialyllactose, but is inactive toward alpha-(2->6)-sialyllactose isomer. Has no activity toward colominic acid, a homomer of alpha-(2->8)-linked Neu5Ac residues.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:10561456}.
Interaction partners:
- 2-hydroxyacylsphingosine 1-beta-galactosyltransferase
- Galactocerebrosidase
- Galactosylceramide sulfotransferase
- Alpha-galactosidase A
- Arylsulfatase A
Sequence:
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEYLPQ
Protein: Exocyst complex component SEC3B (AtSec3b) (Q9SX86)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall.
Interaction partners:
- Exocyst complex component SEC5B
- Exocyst complex component SEC6
- Exocyst complex component SEC5A
- Exocyst complex component SEC8
- Exocyst complex component EXO84A
- Exocyst complex component EXO84C
- Exocyst complex component EXO84B
- Exocyst complex component SEC10a
- Exocyst complex component SEC15B
- Exocyst complex component SEC15A
Sequence:
MAKSSADDEELRRACEAAIEGTKQSIVMSIRVAKSRGVWGKSGKLGRQMAKPRVLALSVKSKGPRKKAILRVMKYSSGGVLEPAKMYDLKHLSKVEVITSDPSGCTFTLGFDNLRSQSVAPPQWTMRNTDDRNRLLVCILNICKDVLGRLPKVVGIDIVEMALWAKDNTPVVTTQRSTEDGEPVAESVTESALKVTVEKELVSQAEEEDMEALLGTYVIGIGEAEAFSERLKRELQALEAANVHAILESEPLVDEVLNGLEAATNIVDDMDEWLGIFNIKLRHMREDIESIEIRNNKLEMQSVNNKALIEELDKVIERLRVPSEYAASLTGGSFDEADMLQNIEACEWLAKALRGLEVPNLDPIYANMRAVKEKRAELEKLKATFVRRASEFLRDYFASLVDFKFSDKSYFSQRGQLKRPDHADLRYKCRTYARLMQHLKGLNKNCLGPLRKAYCSSLNLLLRREAREFAKELRASTKVSRNPTVWLEGSTGSSQNANTDTSAVSDAYAKMLTIFIPLLVDESSFFAHFMCFEVPALAPPGGAGNDKKSQSNNDDGNDNDDLGIMDIDEADKKPGKNSPDLTALNESLQDLLDGIQEDFYAVVDWAYKIDPLRSISMHGITERYLSGQKADAAGFVRLLLGDLESRISMQFSHFVDEACHQIEKNERNVRQMGVLPYIPRFAALATRMEQYIQGQSRNLVDQAYTKFVSILFVTLEKIAQQDPKYADILLLENYAAFQTCLFDLANVVPTLAKFYDQAMEAYEQACTRHISMIIYYQFERLFLFDKKIKDLMYTITPEEIPFQLGLSKVELRKMLKSSLSGVDKSIAAMYKKLQKNLASEELLPSLWDKCKKEFLDKYESFVQLVAKVYPSENVPGVTEMRGLLASM
Protein: Karyopherin alpha 3 (O76522)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTSMEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDEGEQTNMAPSSDGAQYNFDPHADRLTMNSFNF