wanglab/gogpt-training-data huggingface dataset:
Protein: Proline-rich family protein (F4IDX2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSYDRVPPESYPPPGYQSHYPPPGYPSAPPPPGYPSPPSHHEGYPPPQPYGGYPPPSSRPYEGGYQGYFAGGGYPHQHHGPPPPPPPQNYDHCHHDHHHYQDSDSGCFSFIRGCHNVKLKSSVVNPDLTSLSFCLVANYRNFRARDSLAALCCCCLLEECCF
Protein: Complex I intermediate-associated protein 30, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1) (Q9CWX2)
Organism: Mus musculus (Mouse)
Function: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9Y375}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q9Y375}. Note=Periferally associated with the matrix face of the mitochondrial inner membrane. {ECO:0000250|UniProtKB:Q9Y375}.
Interaction partners:
- Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex assembly factor 3
- Complex I assembly factor TMEM126B, mitochondrial
- Complex I assembly factor ACAD9, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- NADH-ubiquinone oxidoreductase chain 2
- NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial
Sequence:
MSSIHKLLTGIYIHKNFLRPRAALPPFVGNHCVDYSSSSLQKKVTSVDRASQQGKTEEGLQGHDHKEVALDAPSPDRTPEVSFDKAIRDEAIEHFRRLKDEIVAHLRGPDGRPLQEVIMEQARVVWQFREKEDLDKWIVTSDKTIGGRSEIFLKMSKNNRSALLYGTLSSEPPQDGDSRQSGYCAMISRIPRGAFERKLSYDWSQFNTLYLRVRGDGRPWMVNIRQDTEFIQRKNQMYSYFMFTRGGPYWQEVKIPFSKFFFSNQGRVRDVQGPLVLDKISSIGFTLSDKVDGPFFLEIDFIGVFTDPAHTEEFAYENSPVLNPRLFR
Protein: Uncharacterized protein Rv2226 (P9WLH9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
Sequence:
MPVEAPRPARHLEVERKFDVIESTVSPSFEGIAAVVRVEQSPTQQLDAVYFDTPSHDLARNQITLRRRTGGADAGWHLKLPAGPDKRTEMRAPLSASGDAVPAELLDVVLAIVRDQPVQPVARISTHRESQILYGAGGDALAEFCNDDVTAWSAGAFHAAGAADNGPAEQQWREWELELVTTDGTADTKLLDRLANRLLDAGAAPAGHGSKLARVLGATSPGELPNGPQPPADPVHRAVSEQVEQLLLWDRAVRADAYDAVHQMRVTTRKIRSLLTDSQESFGLKESAWVIDELRELADVLGVARDAEVLGDRYQRELDALAPELVRGRVRERLVDGARRRYQTGLRRSLIALRSQRYFRLLDALDALVSERAHATSGEESAPVTIDAAYRRVRKAAKAAKTAGDQAGDHHRDEALHLIRKRAKRLRYTAAATGADNVSQEAKVIQTLLGDHQDSVVSREHLIQQAIAANTAGEDTFTYGLLYQQEADLAERCREQLEAALRKLDKAVRKARD
Protein: At3g13310 (Chaperone DnaJ-domain superfamily protein) (DnaJ protein, putative) (DnaJ-like protein) (Q9LTT7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Chaperone DnaJ-domain superfamily protein
- At1g77930
- Heat shock 70 kDa protein 17
- Chaperone DnaJ-domain superfamily protein
- Heat shock protein DnaJ with tetratricopeptide repeat-containing protein
- Chaperone DnaJ-domain superfamily protein
- Chaperone DnaJ-domain superfamily protein
- Chaperone DnaJ-domain superfamily protein
- Heat shock protein DnaJ with tetratricopeptide repeat-containing protein
- Probable ADP-ribosylation factor At2g15310
Sequence:
MAGTLVNSAGRFSPGNCILPQQRTARFYSGTARFPTGAPSFKASAQTLNAEPAVTESVRRRVSSLYELLKVNETASLTEIKTAYRSLAKVYHPDASESDGRDFMEIHKAYATLADPTTRAIYDSTLRVPRRRVHAGAMGRSGRVYATTRRWETDQCW
Protein: Transforming growth factor-beta-induced protein ig-h3 (Q7T1R2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MKRLTLFALAITLIATVFAAKSPYQAVLQHSRIRGRTQGPNVCAMQKIPGSDKKYFTNCKQWYRRKICGKPTVISYECCPGYEKVIGEKGCPAALPLVNIYKTLSVVEATTTKMYSERAKLQEEIEGPGSFTFFAPSNEAWAPLPTEILDALVSNVNIELLNALHYHMINKRLTSEDLKHGSSFSSMHQDFDVHIHHYSNGIVTVNCARLVKTDQHATNGIVHVVDRVITAITNDVNSIIDTDDDLDTLRTAVAAAGLTTLLENQGSYTIFAPTNEAFEKIPPDTLTRILGDPVALKDLLNFHILKNLHCSESIVAGTPLETLQGTMLEVGCDGEDLTINGKAVVTQKDKLGTNGVVHYINELLIPDSAKTLLELAEGSVVTTAAKLFKDAGLNDHLVGSESVTLLAPLNEAFKDKSFAMTPDMKKLLRNHILKEKFSSKSLYHGQELETLGGLKLRVFVFRNNLCIENACIAAHDKNGRYANMFLVDSILTPPQGTVMDVLKADNRFSTLVGAIQKAGLTELLNKKGTYTFFAPTNAAFSALPSADLNKLMRDPKELANILKYHIGDEFLVSGAVTSHTRLKPLAGDKLELGTRNSTIYVNRVPVVESDLMATNGVVHAVNVIIKPLPPKIVSDQAEGSTIRRTSAVRAGSQVSKNDDLFQKVLRSHSSRTLSRVQ
Protein: NKAP-like protein (Q5M9Q1)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q5SZT7}.
Interaction partners:
- Zinc finger protein with KRAB and SCAN domains 4
Sequence:
MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK
Protein: Lipoprotein YghG (Putative pilotin YghG) (Q46835)
Organism: Escherichia coli (strain K12)
Function: Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane. In a functional T2SS this subunit helps assemble the outer membrane channel.
Subcellular location: Cell outer membrane {ECO:0000250|UniProtKB:E3PJ88}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
- Prepilin peptidase PppA
- Putative lipoprotein AcfD homolog
- Putative secretin GspD
- Uncharacterized protein YacC
- Uncharacterized lipoprotein YbfP
Sequence:
MSIKQMPGRVLISLLLSVTGLLSGCASHNENASLLAKKQAQNISQNLPIKSAGYTLVLAQSSGTTVKMTIISEAGTQTTQTPDAFLTSYQRQMCADPTVKLMITEGINYSITINDTRTGNQYQRKLDRTTCGIVKA
Protein: Neurogenin-3 (NGN-3) (Class A basic helix-loop-helix protein 7) (bHLHa7) (Protein atonal homolog 5) (Q9Y4Z2)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- Paired box protein Pax-4
- Transcription factor HES-1
- Hepatocyte nuclear factor 6
- Insulinoma-associated protein 1
- Homeobox protein Nkx-2.2
- DNA-binding protein RFX6
- Insulin gene enhancer protein ISL-1
- Pro-glucagon
- Homeobox protein Nkx-6.1
- Neurogenic differentiation factor 1
Sequence:
MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEERPGLLGATFSACLSPGSLAFSDFL
Protein: Probable conserved integral membrane protein (O53781)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MRVDGRDIGVSGNLLQPLTRRTNDIIRAVLAAIYLVAVITSSLITRPQWVALEKSISEIVGVLSPSQSDLVYLGYGLAILALPFVILIGLIVSRQWKLLGAYAAAGLMAVLPLSISSSRIAAPRWHFDLSDRLATLLAQFLDDPRWIAMLAAVLTVSGPWLPARWRHWWWALLLAFVPIHLVVSAIVPARSLLGLAVGWLVGALVVLVVGTPALEVPLDGAIRALAKRGFAVSGLAVVRPAGPGPLVLSAACEQPNAGACSEALIELYGPHQSGGGALRQLWLKLTLRGTETAPLQASMRRAVEHRALMAIAFGDLGMANTTVIAVSPLDRGWTLYAHRPARGIGISECTKTTPTAHVWEALRTLHDQQISHGDLCSAEITVDNGAVLFGGFGEAEYGATDAQLQSDLAQLLVTTSALYDAEAAVTAAIDTFGKQAILAASRRLTKSAVPKRIRESITDPNAVIASTRAEVMRQTGADQIKAETITRFSRGQLIQLVLIGALVYVAYPFISTVPTFFSQLRTANWWWALLGLAVSALTYVGAAAALWACADGLVGFWKLSIMQVANTFAATTTPAGVGGLALSTRFLQKGGLTAVRATAAVALQQSVQVIVHLVLLILFSALAGTSTDLSHFVPNATVLYLIAGVALGIVGTFLFVPKLRRWLATAVRPKLREVTNDLIALAREPKRLALIVLGCAGTTLGAALALWASIEAFGGGTTFVTVTVVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAALGVPSVLLYRLLTCWLPVFAGWQVMHWLTRHEMI
Protein: AT5g37360/MNJ8_150 (LOW protein: ammonium transporter 1-like protein) (Q93Z11)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transducin/WD40 repeat-like superfamily protein
- Stress response protein
- Probable RNA-binding protein ARP1
- AT2G34560 protein
- Probable ubiquitin-conjugating enzyme E2 23
- Obg-like ATPase 1
- Peptidyl-prolyl cis-trans isomerase FKBP12
Sequence:
MASCSSSSISLLQPLHSLSSSTLFFSQPSFHFSSSLKPNKSKRHNLSKSLTLRFALTESDSTKPLEIEEPSSKSLLLQLSKCFDLPSDYFQQLPNDLRLDLNDAAFDLSNGPVIDECGQELGETLLNLSRAWEQADTSTSRSLVEKLPELEILLTDGARSAFGKRLISAGKRFQGMGQYAKGELQKIAKAMITTGGVLSAKTSSVSVSNESKSGTRMFKFGELQVAVTPEKAYTGAAIAFIYGILSWQISQGIQSIPENSLQYANDNALLIGKSLRGSLLALFYASTVLSGFTTAGLILLAKQLSSEKE
Protein: Importin subunit beta-3 (Importin beta sal3) (O74476)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the nuclear import of cdc25 and mcs1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:12399381, ECO:0000269|PubMed:16823372}. Nucleus envelope {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:12399381, ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:12399381, ECO:0000269|PubMed:16823372}.
Interaction partners:
- Importin subunit beta-1
- mRNA export protein mlo3
- Ubiquitin-like-specific protease 1
- GTP-binding nuclear protein spi1
- Importin subunit beta-5
- Tyrosine-protein phosphatase CDC14 homolog
- Probable importin subunit beta-4
- Importin subunit beta-2
- Importin subunit alpha-1
- Histone H4
Sequence:
MSSGFPPEVLSPLLNLVQGLSSPDNTVRNDAEKSLSSDWISQRADLLLNGLAILAYQSEDPAVRSFCLVLCRRISFRTLPGDSELEVFSSISNESKQSLQSQLLACFVKESVPTVRNKLCDTIAEIARSIYDCQGEWPELINVIFNAVNSPDESFRESVFRTITSLPRLLSGQDSAVTPLFTTGLADPSIRVRISAARAYSAVILESKQSTRDQVIPLLPSLMNILPPLQQDRDSDNLADCLMAITEIAEVFPKLFKPIFESVIAFGLGIIKDKELDNSARQAALELLVCFSEGAPAMCRKSSDYTDQLVLQCLLLMTDVAGDPEDEAEELQEWLNTDDLDQDESDANHVVAEQAMDRLSRKLGGKTILPPSFTWLPRLIPSQKWSERHAALMAISSIAEGAEKLMKKELSRVLDMVLPLLADPHPRVRWAACNAVGQMSTDFAPDMQVKYPSRILEALVPVLESPESRVQAHAAAAMVNFSEEADNKVLEPYLDDILQRLLTLLQSPKRYVQEQAVTTIATVADAAAKKFEKYFDAIMPLLFNVLQQADGKEFRTLRGKTMECATLIALAVGKQRFLPVSQELIQILGNIQMGITDSDDPQASYLISAWGRICRVLGSDFVPFLSSVMPPLLVAATSKPDFTIIDDEVDESKYSEQDGWEFIPVHGQQVGIRTSTLEDKCTATEMLVCYAAELKADFDPYVNEVLTSVVLPGLKFFFHDGVRSACCKCIPQLLNARILASNRDPAKVNELWEPILRKLLDHIQNEPSVEMLADYFECFYQSLEISGLNLSPSSMEALVAAVDLQLKGFISRVQQREEEAKNGDIDIEEDEDMILAVENDQNLLNEINKTFSVVLKIHKTAFCPFWERLLPYMDGFLSGNDTVAKQWALCMMDDLIEFTGPDSWNYKDHFLPYLAEGIQSSEPEIRQAASYGIGVAAQHGGELYAEICSSALPALFKMLELPDARDEEQIYATENICVAICKICRFCSQRVQDLDKVVTYWINTLPVTHDEDDAPYAYTFLAELMEQNHVAVASQMPTIITILAETFASGVLRGRTLTRLMEASKVYLARFPADQVNSVIATLSVDNQRALSAHF
Protein: AT-hook motif nuclear-localized protein (A7TUG5)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU367031}.
Interaction partners:
Sequence:
MDRRDAMALSGSASYYMQQRGITGSGSGTQSGVHGSPGIHPLSSPNVQYQSSISATTMGATLPVEPLSGITPHNVNVGTPPAVQPGETVKRKRGRPRKYGPDGTVSLALTPASATHPGTITPIQKRGRGRPPGTGRKQQLSSLGELLSGSAGMGFTPHVITIAIGEDIATKLMSFSQQGPREVCILSANGAVSTVTLRKPSSSGGTVTYEGRFEILCLSGSYLLTSNTGSRNRTGGLSVSLASPDGRAIGGGVGGMLIAASPVQVIVGSFIWGGSKAKNKKGGQEGIKDSDDQMVDNLVAPPGISPSQNMTPSAPAGVWPGSRSMDMRNNSHVDIDLMRG
Protein: NADP/NAD-dependent aldehyde dehydrogenase PuuC (ALDH) (EC 1.2.1.5) (3-hydroxypropionaldehyde dehydrogenase) (Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase) (Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase) (P23883)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the oxidation of 3-hydroxypropionaldehyde (3-HPA) to 3-hydroxypropionic acid (3-HP). It acts preferentially with NAD but can also use NADP. 3-HPA appears to be the most suitable substrate for PuuC followed by isovaleraldehyde, propionaldehyde, butyraldehyde, and valeraldehyde. It might play a role in propionate and/or acetic acid metabolisms. Also involved in the breakdown of putrescine through the oxidation of gamma-Glu-gamma-aminobutyraldehyde to gamma-Glu-gamma-aminobutyrate (gamma-Glu-GABA).
Interaction partners:
- Gamma-glutamylputrescine oxidoreductase
- Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD
- 4-aminobutyrate aminotransferase PuuE
- Gamma-glutamylputrescine synthetase PuuA
- Methionyl-tRNA formyltransferase
- HTH-type transcriptional regulator PuuR
- Putrescine importer PuuP
- Acetaldehyde dehydrogenase
- Probable alcohol dehydrogenase EutG
- 4-aminobutyrate aminotransferase GabT
Sequence:
MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENETFETVDPVTQAPLAKIARGKSVDIDRAMSAARGVFERGDWSLSSPAKRKAVLNKLADLMEAHAEELALLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGVIAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPDGVLNVVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANIVFADCPDLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLALLKQQAQNWQPGHPLDPATTMGTLIDCAHADSVHSFIREGESKGQLLLDGRNAGLAAAIGPTIFVDVDPNASLSREEIFGPVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVFVNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISLEA
Protein: Epididymal secretory protein E3-alpha (Human epididymis-specific protein 3-alpha) (HE3-alpha) (Q14507)
Organism: Homo sapiens (Human)
Function: Possible function in sperm maturation.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MTSSLKIWGILLALLCILCRLCVYSNNIYWREFIKLHYLSPSREFKEYKCDVLMREKEALKGKSFHMFIYSLWFKIQRACINEKGSDRYRNAYVWAPGALKVLECHWEKYNNRYTESRSFSYIEFHCGVDGYVDNIEDLRIIEPISN
Protein: Albumin (P21847)
Organism: Aquarana catesbeiana (American bullfrog) (Rana catesbeiana)
Function: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood.
Subcellular location: Secreted.
Interaction partners:
Sequence:
KCRIIREFPDIVFKGLTLVQVSQKFGKAGFEDVKKVTEEIVHLNEDCCKGDAVECMMERMEATDHICEAKDKLSSKLADCCAKSILERTPCLLALPNDESDLSKELKNYYEDERVCENYKKDKLLFLAHFTHDYARSHQESSPQSCLRVSKGFEGLLEKCCASENHAECLKQAPILLEAALKEIEELRKQNCGALQLLGFRDYNIQLLFRYFFKMPQVTAPTLVELAGRMTKVAVYCCGLAENKQQTCAEEKLDILLGEMCEKEKHTFVNDNVRHCCVDSYANRRKCFTDLQRYPNYVAPKWDESKLHFNEDLCKGSEDDQIKKKLEVLVEYMKMKPDCGPEKLKEVVEAFRKIDIKCCAAEDHQKCFDDEKAGLLQIIEAH
Protein: Haloacid dehalogenase-like hydrolase (Q381M7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MGDRVGVSFDLVGTLLAVRRSAGYQYGCDLLRFLARKGLQFPAMDERDLEASFKRSMKSEISKSRKVWMENGLGDGEEMPLGGVAPEEVLSFWYRVVDGTFDREGNFCHQDEAMMSAVEEVRQGEDWREFIENTLRRFSTPEPYCWLPEALPTLRALKQWRENDVPPGVCCDPPTLVSNTDSRLVAVIGEMLKDQGETDLLGELFFADAVGAAKPSPQGIIASCKKCGVTSMLHWIHIGDEDEDRVAAARAGCNFLLCSPTKGPVWSELLAKLQEICDSAQSAGQRP
Protein: Developmental pluripotency-associated protein 4 (Q7L190)
Organism: Homo sapiens (Human)
Function: May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8CCG4}. Note=Associated with transcriptionally active chromatin. {ECO:0000250|UniProtKB:Q8CCG4}.
Interaction partners:
- POU domain, class 5, transcription factor 1
- Homeobox protein NANOG
- Transcription factor SOX-2
- Endophilin-A2
- Growth/differentiation factor 3
- Protein lin-28 homolog A
- LINE-1 type transposase domain-containing protein 1
- Developmental pluripotency-associated protein 2
Sequence:
MLRGSASSTSMEKAKGKEWTSTEKSREEDQQASNQPNSIALPGTSAKRTKEKMSIKGSKVLCPKKKAEHTDNPRPQKKIPIPPLPSKLPPVNLIHRDILRAWCQQLKLSSKGQKLDAYKRLCAFAYPNQKDFPSTAKEAKIRKSLQKKLKVEKGETSLQSSETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVESPQEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQEGRVSALFLLPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
Protein: Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed] (Q9H3P7)
Organism: Homo sapiens (Human)
Function: Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:22124328, ECO:0000269|PubMed:27009356, ECO:0000269|PubMed:30755512, ECO:0000269|PubMed:31381608}; Peripheral membrane protein {ECO:0000305|PubMed:31381608}; Cytoplasmic side {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Also mitochondrial (via its interaction with PBR). {ECO:0000250}.
Interaction partners:
- Golgin subfamily B member 1
- Phosphatidylinositol 4-kinase beta
- Translocator protein
- Non-selective voltage-gated ion channel VDAC1
- Golgin-45
- Acyl-CoA-binding protein
- TBC1 domain family member 22A
- Golgin subfamily A member 3
- 3'
- Bifunctional glutamate/proline--tRNA ligase
Sequence:
MAAVLNAERLEVSVDGLTLSPDPEERPGAEGAPLLPPPLPPPSPPGSGRGPGASGEQPEPGEAAAGGAAEEARRLEQRWGFGLEELYGLALRFFKEKDGKAFHPTYEEKLKLVALHKQVLMGPYNPDTCPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVVAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALENGPKESLPVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENIGCEEKAKKNANKPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR
Protein: Candida glabrata strain CBS138 chromosome H complete sequence (B4UN11)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- FACT complex subunit POB3
- Histone H2A
- FACT complex subunit SPT16
- DNA-directed RNA polymerase
Sequence:
MSETRAPRRKTTRRKKDPNAPKRALSAYMFFANENRDIVRSENPDVTFGQIGRLLGERWKALTAEDKQPYEAKAEADKKRYESEKELYNATRA
Protein: Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) (Q9Y2S2)
Organism: Homo sapiens (Human)
Function: Has high L-gulonate 3-dehydrogenase activity. It also exhibits low dehydrogenase activity toward L-3-hydroxybutyrate (HBA) and L-threonate.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P14755}.
Interaction partners:
- 3-ketoacyl-CoA thiolase, peroxisomal
- Aldo-keto reductase family 1 member A1
- Hydroxysteroid dehydrogenase-like protein 2
- 3-ketoacyl-CoA thiolase, mitochondrial
- Acetyl-CoA acetyltransferase, cytosolic
- Sterol carrier protein 2
- Acetyl-CoA acetyltransferase, mitochondrial
- Trifunctional enzyme subunit beta, mitochondrial
- Cocaine- and amphetamine-regulated transcript protein
- Acyl-coenzyme A thioesterase 8
Sequence:
MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEKVNQDMCMKVPDDPEHLAARRQWRDECLMRLAKLKSQVQPQ
Protein: N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (N-terminal RCC1 methyltransferase) (X-Pro-Lys N-terminal protein methyltransferase 1A) (NTM1A) [Cleaved into: N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed] (Q9BV86)
Organism: Homo sapiens (Human)
Function: Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by NTMT2-mediated monomethylation. Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1). Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
Subcellular location: Nucleus {ECO:0000269|PubMed:20668449, ECO:0000269|PubMed:24090352}. Note=Predominantly nuclear (PubMed:24090352).
Interaction partners:
- Regulator of chromosome condensation
- Kelch-like protein 31
- Large ribosomal subunit protein uL23
Sequence:
MTSEVIEDEKQFYSKAKTYWKQIPPTVDGMLGGYGHISSIDINSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFREVDMVDITEDFLVQAKTYLGEEGKRVRNYFCCGLQDFTPEPDSYDVIWIQWVIGHLTDQHLAEFLRRCKGSLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLDVVRRIICSAGLSLLAEERQENLPDEIYHVYSFALR
Protein: Uncharacterized protein (Q5F338)
Organism: Gallus gallus (Chicken)
Interaction partners:
- Uncharacterized protein.
- ERI1 exoribonuclease family member 3.
- Transmembrane protein 53
- Zinc finger C4H2-type containing.
- NIPA like domain containing 4.
- Hyaluronan and proteoglycan link protein 2.
Sequence:
MQSGRRGPGGGGREETFLRVRANRQTRLNARIGKMKRRKQDEGQVCPLCNRPLSGSEEEMSRHVEQCLAKREGSCMTEDDSVDIENENGNRFEEYEWCGQKRIRATTLLEGGFRGSGFIMCSGKENPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEPGEAKEREALRGAVLNGGTPSTRITPEFSKWASDEMPSTSNGESSKQETMQKTCKNSDIEKITEDSAVTTFEALKARVRELERQLSRGDRYKCLICMDSYTMPLTSIQCWHVHCEECWLRTLGAKKLCPQCNTITSPGDLRRIYL
Protein: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain-type isozyme) (RB2K) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] (O35552)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes both the synthesis and degradation of fructose 2,6-bisphosphate.
Interaction partners:
- Fructose-1,6-bisphosphatase isozyme 2
- Hexokinase-2
- ATP-dependent 6-phosphofructokinase, liver type
- ATP-dependent 6-phosphofructokinase, muscle type
- Hexokinase-3
- Fructose-1,6-bisphosphatase 1
- ATP-dependent 6-phosphofructokinase, platelet type
- RCG30218, isoform CRA_b
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
Sequence:
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSFIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNVQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSEAVKIQHFASVVRPSSYTELDFLSVESAKQDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQPLLGKACLRTVCHIFSKFSPY
Protein: Protein SSX5 (O60225)
Organism: Homo sapiens (Human)
Function: Could act as a modulator of transcription.
Interaction partners:
- Protein SSXT
Sequence:
MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTKLGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEGNDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEISDPQEDDE
Protein: Nucleoporin POM34 (Nuclear pore protein POM34) (Pore membrane protein POM34) (Q12445)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000269|PubMed:10684247}. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
Interaction partners:
- Nucleoporin POM152
- Nucleoporin NDC1
- Nucleoporin NUP53
- Nucleoporin ASM4
- Nucleoporin NUP188
- Nucleoporin NUP170
- Nucleoporin NUP157
- Nucleoporin NUP57
- Nucleoporin NUP159
- Nucleoporin NUP133
Sequence:
MKIQAGQLGLDDNDVPGPLPDTDSKPSSQSQNDTPMFKLGNFESPVLKELSRRTVNKEMETQRIMTNVIAFAFWNLLVKFIKFFWNNTHVGRQFCNRLSRIHLYMLTFHTLKKANIIYHTTFSWLNAELLDYLFHLLISLNILFSLWKLLSTVKVSDLNLTDRQKKLLGVDMQSSVDTGLQPQHPHYVSTSKISQMAQNKTHIPQTNLKNHPAYLFKGLETPLKARQREMAEEQTKLQSQSLHTKNVFGTLQRHSGISSTLVSANNDNNSPHTPVTRKGYIPSSKYAYMMNSQSPRGKI