wanglab/gogpt-training-data huggingface dataset:
Protein: Without children, isoform D (A0A0B4KI43)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MEEISSLDSFGADSNARPESATPRSEEQQDQDRQQTAPAASETLDTPASPPAEDAAAQESKPPPSKEADDDFEQISEGSLDADDNQSRDKAASTPADPVDAEEPAEEPTPNEEPQGGEDEQPQTEAVRVDPQEEPEEAEEETDALQATAEEVEAAAAEADAVDGGPASPEAMDVDEGEVDAEGEAEQEAEDDAALDREATDDVDMQSVGADSHQAEDAEPPEGRDEVDTSLEEQENGQDPDEREKDAAADEDDPDAEGDAESEQVDENAEETGEAEHGDDTVENVLEPEESDVCLIPDDQETEVTEAEKELARENAEKAAEEEEAEERQAKTPDNDRKSPADAAADPEDDSAAAVDATDVSPTTPTDGVAAAANEEEAGGDVPDPDEPTAEESSSAGAGEPGSTPKIIISWIVGSVQKCKQCGDEKNCGFRYRSPEESEEMDKEKENDKAEENAEEGEEEEARQKPAAPSGFEYICDTACVDALLEDQPGKYFVRRKKFLVEEVVREEGAAEAEASADGEGGDAEEEATPANTQDCLQCKDKTRCKYFIKQDQDCFYICNDDCFNLLNAEEPDKFKLKRHSIRVRNIGATTLQPPQNSPTKRTDGSVVARTVEEAETARLDRIESFRRRCADCEADINTDEKQLMWETMDFCNEVCLGSYQRTIGSTCETCKQEVSSIALGKYCVRFGFDVRQFCCAGCLNTFKKGLKTCSCCQKDISGGQEGFLAPVGDKDQFKDFCSQSCLRRYESMCNPRRKLRTDVCGVCNNQKPVRVEMLLEDREHYFCSNPCFSAFKFVSNVNADPCAMCSKYFERRSAESYTIYNEQQSPKVFCSRVCINVYIIVNRHIVSCQWCKVKKYNFDMIYQIGGPHDQETLTCSINCLTMHGVSCNISARAVTKCDNCSNFNTPQYHLTMSDASMRNFCTYQCVMQFQNQFARAPLTLDSDLPPSSAGSSKSQQQSNRGNKNAAPFPTGLPKRVKLKLSHTGKGGVGGKKSGSGTMLPVISTVQSLASGETEARIGNLTVRRKRGRPRESGTSSPPLSMPGVHPPAQRGRPRKHAVDYSARSPSPTMSGGSSHMGIPVRRNTTTTMDFGPATVTETKIITVPPYPKAVRNVNISCKPLTVTQGEQCSPDVRDCATQTEKDYSNKVLIPVPVPIFVPQPMYMYSAPFPVPVPIPLPIPVPIFIPTTRNTAQGILKEIKKIQDKMPEDPLEAELLMMAEMVAEEKHESDSDSDNEIKPDPGLVALQYQNSLESVAQQQQQQQVVDVSGAGHNPYGDDMLQIALKMATGDYDNHHQTSTVDLETSMTANTISSQSPMGHDGMGQMGVHHLDQQHHMLDATQRTARGRKRGVGVVMDPPNRNSRSPVKRQRGGEMDHSALQQQSQQAQQPQEKPDAQMFLKYTFGVNAWKQWVMTKNADIEKSSMRRRPFKTELLQMTADELNYSLCLFVKEVRKPNGTEYAPDTIYYLVLGIQQYLYVNGRIDNIFYDPYYERFTECLDEVARKFSVLYNDSQYIVTRVEEEHLWECKQLGAHSPHVLLSTLMFFNTKHFNLTTVEEHMQLSFSHIMKHWKRSSQNSKVPGSRNVLLRFYPPQAGLDANPRKKKVYEQQENEENPLRCPVRLYEFYLSKCPESVKTRNDVFYLQPERSCVPDSPVWYSTQALGQDALQRMLHRVKMVKEINIALLTT
Protein: Kinesin-like protein KIFC1 (CHO2 antigen) (Q60443)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:7744954}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:7744954}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:7744954}. Early endosome {ECO:0000250|UniProtKB:Q9QWT9}. Note=Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis. {ECO:0000250|UniProtKB:Q9QWT9, ECO:0000269|PubMed:7744954}.
Interaction partners:
Sequence:
MKEALEPAKKRTRGLGAVTKIDTSRSKGPLLSSLSQPQGPTAAQKGPKKTGPRGCTAVGSVLKNQKLAPTAPAQKPVRKRPGKRPDWDLKGQLCDLTEELKCYREKTQKLDQENQGLQEQLKEAQEQAAALGTERNTLEGELASVRTQAEQCQQKLEALCARVLELEEWLGTKENLIQELQKEQLELQEERKALATRLEEQERRLQASEAALLSNESEVVCLRQKTAAQVTLLAEQGDRLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLAGEPTPSPGFLLFPHGPAGPSDPPTRLSLSRSDDRRSTLTRAPAPTTRHDFSFDRVFPPGSKQEEVFEEISMLVQSALDGYPVCIFAYGQTGSGKTFTMEGRPGGDPQLEGLIPRRMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGECEIRRARPGSEELTVTNARYVPVSCEREVEALLHLAHQNRAVARTAQNERSSRSHSVFQLQISGEHAARGLQCVAPLNLVDLAGSERLDPGLTLGPGERDRLRETQSINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK
Protein: Auxin-responsive protein IAA3 (Indoleacetic acid-induced protein 3) (Q5NB25)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Auxin response factor 11
- Auxin response factor 9
- Auxin response factor 7
- Transport inhibitor response 1-like protein Os05g0150500
- Auxin response factor 3
- Auxin response factor 15
- Auxin response factor 14
- Auxin response factor 2
- Auxin response factor 1
- Auxin response factor 16
Sequence:
MSPPLELDYIGLSPPPPPPSSSSAAAARADDVDLKGTELRLGLPGSESPDRRPAAIAAAAATATTLELLPAKGAKRVFPDEAALTPPTAAAGKGKAAREGEEVGAEEEDKKVAAPPQPAAKAQVVGWPPIRSYRKNTMATNQIKSNKEDVDAKQGQGFLYVKVSMDGAPYLRKVDLKTYKNYKDMSLGLEKMFIGFSTGKEGAENQKDGEYVLTYEDKDGDWMLVGDVPWEMFTDSCRRLRIMKGSDAIGLAPRAGEKSKNRN
Protein: Destrin (Actin-depolymerizing factor) (ADF) (Sid 23) (Q9R0P5)
Organism: Mus musculus (Mouse)
Function: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
Interaction partners:
- Cofilin-2
- WD repeat-containing protein 1
- Profilin-4
- LIM domain kinase 1
- Profilin-1
- LIM domain kinase 2
- Profilin-2
- Profilin
- Profilin-3
Sequence:
MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIVVEEGKEILVGDVGATITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPEQAPLKSKMIYASSKDAIKKKFPGIKHEYQANGPEDLNRTCIAEKLGGSLIVAFEGSPV
Protein: Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC 3.1.3.48) (B2GV87)
Organism: Rattus norvegicus (Rat)
Function: Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity). Acts as a negative regulator of insulin receptor (IR) signaling and is involved in insulin-induced glucose metabolism mainly through direct dephosphorylation and inactivation of IR in hepatocytes and liver.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000250}. Note=Predominantly cytoplasmic. A small fraction is also associated with nucleus and membrane. Insulin can induce translocation to the membrane (By similarity). {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm {ECO:0000250}.
Interaction partners:
- 6-pyruvoyl tetrahydrobiopterin synthase
Sequence:
MEPFCPLLLASFSLSLATAGQGNDTTPTESNWTSTTAGPPDPGTSQPLLTWLLLPLLLLLFLLAAYFFRFRKQRKAVVNSNDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHCRVILSQLDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQRSATIVMLTNLKERKEEKCYQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIHPQLPDSCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYGDTELDVSSLERHLQTLHGTATHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFMATQGPLAHTVEDFWRMVWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGDITIEIKSDTLSEAISIRDFLVTFKQPLARQEEQVRMVRQFHFHGWPEVGIPTEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK
Protein: Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) (O35316)
Organism: Mus musculus (Mouse)
Function: Mediates sodium- and chloride-dependent transport of taurine. Can also mediate transport of hypotaurine, beta-alanine and gamma-aminobutyric acid (GABA).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P31641}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFHSFQKDLPWAHCNHSWNTPQCMEDTLRRNESHWVSLSTANFTSPVIEFWERNVLSLSSGIDNPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPDISRLGDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAILCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPALCVGCFVFSLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMLCIPLVIVILLCRTEGPLRVRIKYLITPREPNRWAVEREGATPFHSRVTLMNGALMKPSHVIVETMM
Protein: GM10231p (Q9VSB8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLPQTPPHGLKVMSGAEENRHYLRAFIQTYRDLPVLWDTSLRDYTNREKRAEAYLRLVPIYHYLKRDATVEDVKKKINTLRTNYRKELKVVESALRSGSLHSPRCWTFQELDFLRNSEKFLAVNPAFKNEPNFAFGESSNCPSAFLESQGAALHYPAPRAGGQTPNISEMFHKSFGAPPPPPPATNHVDYGSSKRARQTPPCTGAGAGSTGGPGATGTAHNTDELLNIACEYLAGTYPEEESIARTWTHKLKRLPREQRLLAERFINEILFEAESNNLHRGSVQINNSFEPYVRYEETPNGHEEQDKSQSPSVHTSSESKPNVSGASGSGGGGGPPGSTTTSAGIREF
Protein: Density-regulated protein homolog (Q9VX98)
Organism: Drosophila melanogaster (Fruit fly)
Function: Regulates translation as part of a complex with MCTS1. Specifically required for translational re-initiation in mRNAs containing upstream open reading frames (uORFs). Not required for standard translational initiation. Regulates expression of a subset of gene products including mbc, InR and EcR.
Interaction partners:
- Malignant T-cell-amplified sequence 1 homolog
- Eukaryotic translation initiation factor 2D
- Eukaryotic translation initiation factor 5
- Protein Pixie
- Eukaryotic translation initiation factor 2 subunit 1
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 4C
- Eukaryotic translation initiation factor 2 subunit 2
- Eukaryotic translation initiation factor 3 subunit C
- Small ribosomal subunit protein uS3
Sequence:
MTNEDVGTNSVADRLQLGPREGVTYPIQMKYCGHCTMPIEYCEYYPEYEKCKEWLELHMPDDFERLKIEEEAAAADGTDDDKKRQKRGGKGLLRVKKKEDVPKRICVSRAARGKKKSVTVVTGLSTFDIDLKVAAKFFGTKFACGSSVTGDDEIVIQGDVKDDLFDVIPEKWAEIDEDVIEDLGDQKRT
Protein: Autophagy-related protein 9 (AtAPG9) (Q8RUS5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity). In addition to autophagy, also plays a role in necrotic cell death (By similarity). Plays an essential role in plant nutrient recycling.
Subcellular location: Preautophagosomal structure membrane {ECO:0000269|PubMed:24249832}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Beclin-1-like protein
- Serine/threonine-protein kinase VPS15
- Phosphatidylinositol 3-kinase VPS34
- Ubiquitin-like modifier-activating enzyme atg7
- Serine/threonine-protein kinase ATG1c
- Serine/threonine-protein kinase ATG1b
- Autophagy-related protein 2
- Serine/threonine-protein kinase ATG1a
- Autophagy-related protein 16
- Autophagy-related protein 3
Sequence:
MMSSGHKGPNVRNFFKWQRGESSSSLTTGLLHNESHEIELSNYGGIPSPGSESPSGLLNGESLNVQPIADLDLFVERLYSYYRDKGLWCIIVKWAVELLSLGFIICFSGFFLLYVDWNGLQNAKCGMDAVESGTKPCDLVKEAIHPHPLSPFTLTTAIIVGYLALFSVYWLFCFLRFFAQLKDTLDFRHFYYNNLHVTDNEILTMPWATVLEKVVQLQSSQCLCVVKDLSAHDMVMRLMRKENYLIGMLNKGLLSFPISHWIPGAGPAVKSAPDGTQYHLVLTKTLEWTLNWCILQSMFDCNFRVRRDFVSNPTTLKKRLFVVGLAMLLLSPFLVIFMLVYLFLRHAEQFYNHPSTASSRRWSNLSKWLFREFNEVDHLFKHRINSSVVHASEYLKQFPSPIISIIAKFVSFVSGGFAAVLIIIAFLEESLLEGHIFGRNLFWYAAVFGTITAISRAAISDELLVLDPVGTMSLVVQNTHYMPKRWRGKENKDDVRLELETLFQYTGMMLLEEIASIFITPFLLMFVVPKRVDDILQFIKDFTVDIEGVGHVCSFSAFYFENHGNIKYGSPHNATRREQRSSQGKMEKSFLSFQSSYPSWESDSLGKQFLSNLRTFRDRKLHEINTRHSSPSRAWRESTNTPALYRDIPRNPLASGNHTDSMWLIDPDQRNHPYLLDWYYTSQAHNRTDHPIERANEILTANQNATDCWPPDLGIRGEDSRDLLNMEASTSGQFFRESILRHDQPEGEDSYGSQHPLDGRNQWWGRGNHSQISTAHPATTNSFIEPPDFINRYTAGNLLDNSWSRRSIEEEDEEEEELDWEENARRNLSRTTFMDDNDIEAGIDLHFDDVYSSRPQETSTSSTTLR
Protein: Protein-arginine omega-N methyltransferase (Q5A943)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Small ribosomal subunit protein uS5
- Histone H4
- mRNA-binding protein
- rRNA 2'-O-methyltransferase fibrillarin
- mRNA-binding ribosome synthesis protein
- mRNA-binding protein
- RRM domain-containing protein
- Mtr10p
- SnoRNA-binding rRNA-processing protein
- Signal peptidase complex subunit 2
Sequence:
MSESATDKSQLSKFEQHYFSSYDHFGIHEEMLKDTSRTLSYRNAMYRNKDLFKDKIVLDVGCGTGILSMFAVKAGAKHVYSVDMSSIIDKAKEIVELNGFSDKITLLQGKLEDINLPVDKVDIIISEWMGYFLLYESMLDTVLYARDRYLVEGGLIFPDKCQMYIAGIEDAQYKDEKIHYWEDVYGFDYTPFIKTAMEEPLVDTVNNQSLITKGTQFFEFDINTVTKEQLSIKRKFELQAIDNDYCHAFIVYWDAVFPGKQRVILPTGPMHQYTHWKQTVFYMDQVLDLKKGDTINGEITAVPSKINPRELDIDISWEVKTQANDKSRELKGGYTYFLR
Protein: Transcription factor bHLH121 (Basic helix-loop-helix protein 121) (AtbHLH121) (bHLH 121) (Transcription factor EN 138) (bHLH transcription factor bHLH121) (Q9LT23)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- LOB domain-containing protein 30
- Transcription factor bHLH100
- Transcription factor bHLH101
- Dehydration-responsive element-binding protein 1E
- Potassium transporter 5
- Fe
- Dehydration-responsive element-binding protein 1F
- Transcription factor ORG2
- Ferric reduction oxidase 2
- RNA-binding
Sequence:
MGIRENGIMLVSRERERARRLENRESIFAEPPCLLLAHRISPSPSILPAEEEVMDVSARKSQKAGREKLRREKLNEHFVELGNVLDPERPKNDKATILTDTVQLLKELTSEVNKLKSEYTALTDESRELTQEKNDLREEKTSLKSDIENLNLQYQQRLRSMSPWGAAMDHTVMMAPPPSFPYPMPIAMPPGSIPMHPSMPSYTYFGNQNPSMIPAPCPTYMPYMPPNTVVEQQSVHIPQNPGNRSREPRAKVSRESRSEKAEDSNEVATQLELKTPGSTSDKDTLQRPEKTKRCKRNNNNNSIEESSHSSKCSSSPSVRDHSSSSSVAGGQKPDDAK
Protein: Olfactory receptor 10J5 (Olfactory receptor OR1-28) (Q8NHC4)
Organism: Homo sapiens (Human)
Function: Olfactory receptor. Activated by the synthetic floral odorant, lyral, and by alpha-cedrene, a sesquiterpene constituent of cedarwood oil. Its activation increases intracellular Ca(2+). Acts as a key regulator of myogenesis through its actions on cell migration and adhesion by activating the Ca(2+)-dependent AKT signal transduction pathway (By similarity). Acts also as a regulator of angiogenesis. Moreover, plays a role in the regulation of lipid accumulation in hepatocytes via the cAMP-PKA pathway. May be involved in sperm chemotaxis and motility (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:28842679}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Adenylate cyclase type 3
Sequence:
MKRKNFTEVSEFIFLGFSSFGKHQITLFVVFLTVYILTLVANIIIVTIICIDHHLHTPMYFFLSMLASSETVYTLVIVPRMLLSLIFHNQPISLAGCATQMFFFVILATNNCFLLTAMGYDRYVAICRPLRYTVIMSKGLCAQLVCGSFGIGLTMAVLHVTAMFNLPFCGTVVDHFFCDIYPVMKLSCIDTTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGRKKTFATCVSHLTVVIVHCGCASIAYLKPKSESSIEKDLVLSVTYTIITPLLNPVVYSLRNKEVKDALCRVVGRNIS
Protein: Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF) (P13804)
Organism: Homo sapiens (Human)
Function: Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism.
Subcellular location: Mitochondrion matrix {ECO:0000305}.
Interaction partners:
- Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
- Electron transfer flavoprotein subunit beta
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Electron transfer flavoprotein regulatory factor 1
- Ganglioside GM2 activator
- Acyl carrier protein, mitochondrial
- Short-chain specific acyl-CoA dehydrogenase, mitochondrial
- Isobutyryl-CoA dehydrogenase, mitochondrial
- Large ribosomal subunit protein uL3m
Sequence:
MFRAAAPGQLRRAASLLRFQSTLVIAEHANDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAATSGGSASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK
Protein: Enterobactin biosynthesis protein YbdZ (P18393)
Organism: Escherichia coli (strain K12)
Function: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. Plays a role in the catalytic function of EntF. It is required for adenylation of amino acids in non-ribosomal peptide biosynthesis.
Interaction partners:
- Enterobactin synthase component F
- Enterobactin synthase component B
- Iron
- Enterobactin synthase component E
- 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
- Ferrienterobactin receptor
- Enterobactin synthase component D
- Enterobactin exporter EntS
- Isochorismate synthase EntC
- Acyl carrier protein
Sequence:
MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCVLPAGWDIVCQPQSQASCQQWLEAHWRTLTPTNFTQLQEAQ
Protein: Myb protein (P04197)
Organism: Drosophila melanogaster (Fruit fly)
Function: DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- LD07342p
- Lin-52, isoform A
- LD06557p
- Protein lin-54 homolog
- Chromatin assembly factor 1 p55 subunit
- Transcription factor E2F2
- RE32990p
- Retinoblastoma family protein
- Transcription factor Dp
- Histone deacetylase HDAC1
Sequence:
MASASTENGEELMNYGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHGENWEIIGPHFKDRLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSVNASGSDLKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSENADGASVTAVKGGDLAQESQDDHQKGSNLAHLSMQHLIKLTMPRQTPIILKRTRKHIPETHHQAGCSSSETFNQEEAAGNARSRPPSSPVISPIKSLPFSPSHFLKSPCLTTFEDMDLRASTPVTKVYNRVGMEIKKEMETSSIETPHKSQLGPRTPTPFKKALAAIGKKRDGRRYEPSSPSSLVEDLAEIIHEEHLSNSLTANNSKMMGAADQNSTLSTEYNAQSPPHMKRARKSLLSTWSSNHPYNAGSAKRIQPFETETPSKFLTSPGDILKDTLCSEQDLPFDEGRKENRPFHNRRINKYRGGLTYDHVIDPKWARVACGKSRDQMFMEEQAYACLKNLSCISRSLNFEKQKCLVNSFDRFGSL
Protein: ZH8 protein (Q1RP76)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MIPPSAQPPRTQTPPVGQTPQLGLKTNPPLIQEKTAKTSKEPPPSKEELLKLTEAVLTEYLNSGNANNAVSGVREMRAPKHFLPEMLSKVSILSLDRSDEVKEKASSLINLLKQEGIAASDNFMQVFLNVLEQCPKLEVDIPLVKSYLAQFMARAIISDLVSISELAQPLESGTHFPLFLFCLQQLAKLQAQEWLAELFKQSKVNMQKMLPENDQNKDQMLEILEGKGLSFLFPLLKLEKKLLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD
Protein: Dynein regulatory complex protein 9 (IQ domain-containing protein G) (Q80W32)
Organism: Mus musculus (Mouse)
Function: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades (By similarity). Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24849454}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:24849454}. Cell projection, cilium {ECO:0000269|PubMed:24849454}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24849454}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A8HQ54}. Note=First detected in the cytoplasm of pachytene spermatocytes. Colocalizes with alpha-tubulin at the manchette in developing spermatids. Detected in the flagellum of mature testicular spermatozoa, and in the flagellum and post-acrosomal region of the head of epididymal spermatozoa. Detected in cilia in trachea and oviduct. {ECO:0000269|PubMed:24849454}.
Interaction partners:
- Dynein regulatory complex subunit 5
Sequence:
MDEEEVEVVESPSEVLQPEVTVVVTGEPPEAAEEDLDYEEEEETSPEVIETLSLLDVLRVSAVMEDVIDQLSILGYIIPVQYERRQSLTQKASHEGASMITTTPKKSTSLLTKEKSMMAENKQRGQDFTFKKPTKQTMMTLETLKKIQNDRQYFSDVIANAMMEMQDSGSFTSLLKALGKERDSKMNFHDVITREEKGRKQIKTLQKQLLDVKRERQMQVQNGNEYIAHLRDQLQEMKAKTNLENLYMKRNAELQISQTQKKCNRAEELLLEEIEKLRMKTEEENRVHTEIEMFLKKQQQKLEEKLEFWMEKFDKDTEAKQNELNALKAAKASDLVHLQDLAKMIREYEQVIIEDRIEKEKTRKKLEQDDLELRSIVKLQAWWRGSVVRKEIGNFKMPKKDKDDSKDSKGKEKEKRRKK
Protein: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) (Q97NG1)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00022}.
Interaction partners:
Sequence:
MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIEDTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKAYKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAVNESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGDDHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYLPEAVFNFIALLGWNPGGEDEIFSREEFIKLFDENRLSKSPAAFDQKKLDWMSNDYIKNADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEAEREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRIAVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK
Protein: RE50471p (Q8SYN6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSEVQTLMDMGFPRERVEYALEVTSNKGVEPAMEWLLAHVDDPIPSRQGAGESPGSTAQPAAAVDSSAAAASSSTSGAGETSAPVAKSLKCDECKVLRDHTEVEYHAAKTGHTKFSESEEEKKALTEEEKKAQLALIEEKLKQKRIEREEREKIEALQREKNRIKSGKDMTEAKRRMEELEMKKIVEQRKREKDEEKAARDRVKAQIEADKAARKAREQKELGNAEPAPSVSSTTVSSPPAGVKSPPRDYTETRIQVRLQDGSTLQETFNVKEQLSAVRVFIQMKTGIESPFSLMTTFPRKLFAEDDYEKPLEVLGLVPSAVITMTKTPA
Protein: Putative ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (P34539)
Organism: Caenorhabditis elegans
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular location: Mitochondrion. Mitochondrion inner membrane.
Interaction partners:
- ATP synthase subunit d
- ATP synthase F
- Oligomycin sensitivity conferral protein
- F-ATPase gamma subunit
- ATP synthase subunit delta, mitochondrial
- ATP synthase subunit beta, mitochondrial
- Probable ATP synthase subunit g 2, mitochondrial
- Putative ATP synthase subunit f
- ATP synthase subunit a
- Probable ATP synthase subunit g 1, mitochondrial
Sequence:
MVAWRAAGLNYVRYSQIAAQVVRQCTKGGANVKKPQATLKTTAWENGKMVSKSQ
Protein: Protein kinase C delta (C9K0E3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFDAHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQYFLEDVDCKQSMRSEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRHCGMNVHHKCREKVANLCGINQKLLAEALNQVT