Protein: Fibronectin (FN) (P11722)
Organism: Gallus gallus (Chicken)
Function: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (By similarity). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).
Subcellular location: Secreted, extracellular space, extracellular matrix.
Interaction partners:
- Collagen alpha-1
- Elastin
- Syndecan-4
- SMB domain-containing protein.
- Integrin beta
- Link domain-containing protein.
- Integrin beta
- Integrin beta
- Integrin beta-1
- Integrin beta
Sequence:
MPGRGGLRLALLALCLGAAAAGGGDGQRRGGKNRRQAQTASVPQATPAQGKQTCFDNGRYYQINQQWERIYLGNTLVCTCYGGSRGFNCESKPEPEETCFDKYTGSTYRVGETYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGKSYKIGDTWRRPHETGGYLLECVCLGNGKGEWTCKPLAERCYDNTAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTKTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSLHTTSTGSGSPSFTNVQTALYQPQPQQPQPQPHGHCVTDNGVVYSLGMQWLKTQGSQQMLCTCLGNGVSCQEIAVTQTYGGNSDGEACVLPFTYNGRTFYSCTTEGRTDGHLWCSTTSNFEQDRRYSFCTEQNVLVQTRGGNSNGALCHFPFLYNNRNYTDCTSEGRRDNMKWCGTTENYDADQKFGFCPMAAHEEICTTNDGIMYRVGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDGITYDVNQTFHKRHDEGHMLNCTCFGQGRGRWKCDPVDQCQDSETRTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQAYAGATGPVQVIITESTNQPNSHPIQWNAPKTSHISKYILRWRPKISGRHWKEATIPGHLNSYTISGLKPGVVYEGQLISVQQHGPKEVTRFDFTTTSTTAVTSNTVSGETTLLPPMVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEEGEQNLILSTSQTTAPDAPPEHSVESVDDTSIVISWSRPQAPITGYRIVYTPSVEGSSTELNLPDTATSVTLSDLMPGVQYNISIYAVEEHQESTPVFIQQETTGVPRTDEVPSPKDLQFVEVSDVKVTIMWTPPQSQVSGYRVEAIPVNRPGQHGQRLPITRSSFAEVVDLLPGTTYLFKIFAVSHGRESKPLTGEQTTKLDAPTNLRFINTTEHSVLVLWTRPRAIISGYRLTAGPTRGGQPRTYNVGPSATKYLLRNLQPGTEYTVYLVAVKEDLQSARETGVFTTYQPVGSVPPFNTEVTETSIVITWTPAPRIGFKLGVRPSQGGEAPREVISDSGSIVISGLTPGVEYTYSLTVLMDGQERETPIIRRVTTPLSPPTNLRLEPNPDTGILIVSWDRSTTPGISGYRVTTAPTNGQQGSTLEEVVGADQTSCTFENLNPGVEYNVSVYAVKDDQESIPISKTITQEVPQLTDLSFVDITDSSIGLRWTPLNASTIIGYRITVVAAGESVPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNVGPDTMRVTWTAPTSIVLSSFLVRYSPVKKEEDVAELTISPSDNVVVLTNLLPGTEYLVRVYSVAEQHESAPLSGIQKTGLDSPTGLDFSDITANSFTVHWIAPRATITGYKIRHHPEHGVGRPKEDRVPPSRNSITLTNLLPGTEYVVSIIAVNGREESVPLVGQQTTVSDVPRDLEVNPTSPTSLEISWDAPAVTVRYYRITYGETGGSSPVQEFTVPGTMSRATITGLKPGVDYTITVYAVTGRGDSPASSKPVTVTYKTEIDTPSQMQVTDVQDNSISIRWLPSSSPVTGYRVTAVPKKGHGPTKTKNVPPDQTQVTIEGLQPTVEYMVSVYAQNQNGESLPLVETAVTNIDRPKGLTFTEVDVDSIKIAWESPQGQVTRYRVTYSSPEDGIHELLPAPGGEEDTAELHGLRPGSEYTINIVAIYDDMESLPLTGTQSTAIPPPTNLKFTQVTPTSLTVNWNAPNVRLTGYRVRVNPKEKTGPMKEINLSPDSTSAVVSGLMVATKYEVSVYALKDSLTSRPAQGVVTTLENVSPPRRARVTDATETTITITWRTKTETITGFQIDAIPAASGQNPIQRTISPDVRTYTITGLQPGNDYKIYLYTLNENARSSPVVIDASTAIDAPSNLRFLTTTTNSLLASWQPPRAKITGYIIRYDKPGSPAKELLPRPRPGTTEATITGLEPGTEYTIYIIAVKNNQKSEPLVGRKRTDDLPTLITGPHPNQPDMLDVPSVDEGTPYLTNNRYDNGNGIQLPGTSGHPQTIGHQGQQVFFEEHGYRRPVPTTATPLRPGSRRQPPNVDEAIEIPGYQVPIIVVPSYPHSREPRRNDTTGQEALSQTTISWRPLLESTEYIISCQPVSQDEDTLQFRVPGTSSSATLTGLTRGATYNIIVEALKDHRRQKVLEEVVTVGNTVSEGLNQPADDTCYDTYTGSFYSIGEEWERLSETGFKLWCQCLGFGSGHFRCDSSKWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCEPHETTCYDDGKMYQVGEQWQKEYFGAICSCTCYGGQQGWRCDNCRRPSVEVAPEGSAGHTYPQFTQRYHQATNTNVNCPIECFMPLDVQADTQHPRGK