wanglab/gogpt-training-data huggingface dataset:
Protein: Helicase ATP-binding domain-containing protein (Q93413)
Organism: Caenorhabditis elegans
Interaction partners:
- RNA-directed RNA polymerase
- Tudor domain-containing protein
- RNA-directed RNA polymerase
- Endoribonuclease dcr-1
- Probable ubiquitin carboxyl-terminal hydrolase K02C4.3
- DRBM domain-containing protein
- 3'-5' exonuclease eri-1
- Tudor domain-containing protein
- RNA-directed RNA polymerase
- Piwi domain-containing protein
Sequence:
MQPTAIRLEDYDKSKLRLPFESPYFPAYFRLLKWKFLDVCVESTRNNDIGYFKLFESLFPPGKLEEIARMIIDEPTPVSHDPDMIKIRNADLDVKIRKQAETYVTLRHAHQQKVQRRRFSECFLNTVLFDEKGLRIADEVMFNYDKELYGYSHWEDLPDGWLTAETFKNKFYDEEEVTNNPFGYQKLDRVAGAARGMIIMKHLKSNPRCVSETTILAFEVFNKGNHQLSTDLVEDLLTEGPAFELKIENGEEKKYAVKKWSLHKTLTMFLAIIGFKSNDKKEKNEHEEWYYGFIDAMKNDPANRAALYFLDKNWPEELEEREKERDRIRLTLLKSQRTNEEAVGEDVCTTIRPQPKDSGYNPDAVVTELVLRTYQEELVQPALEGKNCVIVAPTGSGKTEVAIYAALKHIEERTSQGKPSRVVLLVPKIPLVGQQKDRFLKYCNGMYEVNGFHGSESSVSGTGRRDEVIATHVSVMTPQILINMLQSVRQNERLYVSDFSMMIFDEVHKAAKNHPYVLINQMVQEWKYEKPQIIGLTASLSVKVDGQKDENQMLNDIYNMLALINAPHLSTITRQSSIDELNEHVGKPDDSVELCLPAKENILRDYIERYLNHAHGKFLEELASMSKSTGRNNTIPPNMINTFKKNQPKNYEYYDSLLQGIIQELNKLNVPEKWNSQTWAKYMKVYLEARGIVDLMPAMVAFKYMEKAIGKLNESHSETVEYSTFIKDHDTLKQTIQSVEPEIVLRLKNTLTNQFHVAPESRVIIFVTQRSTAQRVSDFLNESKVLDQFGNYGEQMVGYVLGTNKQGAVQQTSQEQQLTLDKFNNGRLKVIVATSVVEEGLDVTACNLIIKYNCSSGSAIQLVQQRGRARAKNSRSVLLSVKSSINETETNALISEKYMRLCVKKITENGEKQLAAEVKRVAELNAAERKRNLEEQLNLRLRHENKIYKLMCSNCSKEFCKSIYIKKVFSNYMVFDPSVWRFLHVESKRKVSKYLSEDNQPLSDIKCFHCKLDVGRAYKIRGTYLPQLSVKALTFVQESDYSSMTKAKWSDVEQDLFYISEAIEDDFRIMLNALSDTEENIEKKIVLDLDSRQHNKQLEMKRFHIQQEPPTKGVAPEAQ
Protein: Neural Lazarillo (Q9NAZ4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNHHSSSHLLLLISVVFGAVWVAHAQVPFPGKCPDVKLLDTFDAEAYMGVWYEYAAYPFAFEIGKKCIYANYSLIDNSTVSVVNAAINRFTGQPSNVTGQAKVLGPGQLAVAFYPTQPLTKANYLVLGTDYESYAVVYSCTSVTPLANFKIVWILTRQREPSAEAVDAARKILEDNDVSQAFLIDTVQKNCPRLDGNGTGLTGEDGLDVDDFVSTTVPNAIEKA
Protein: Gluconate 5-dehydrogenase (EC 1.1.1.-) (D-gluconate 5-dehydrogenase (NADP)) (Gluconate:NADP 5-oxidoreductase) (GNO) (P50199)
Organism: Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Function: Catalyzes the reversible NADP-dependent oxidation of gluconate to 5-ketogluconate. Is involved in the non-phosphorylative, ketogenic oxidation of glucose. Is almost inactive with NAD as cosubstrate. Displays high substrate specificity since D-Glucose, D-sorbitol, and D-mannitol are not oxidized by the enzyme, and 2-ketogluconate and L-sorbose are not reduced. Can accept D-fructose as a substrate, with a rate that is only 10% of the rate of 5-ketogluconate reduction.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:7751271}.
Interaction partners:
Sequence:
MSHPDLFSLSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVFDVTDQDAVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAVFFVGQAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGLQINGLAPGYFATEMTERLVADEEFTDWLCKRTPAGRWGQVEELVGAAVFLSSRASSFVNGQVLMVDGGITVSL
Protein: Glycerol-3-phosphate acyltransferase 2, mitochondrial (GPAT-2) (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase GPAT2) (EC 2.3.1.51) (xGPAT1) (Q6NUI2)
Organism: Homo sapiens (Human)
Function: Transfers an acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate producing a lysophosphatidic acid (LPA), an essential step for the triacylglycerol (TAG) and glycerophospholipids. In vitro also transfers an acyl-group from acyl-ACP to the LPA producing a phosphatidic acid (PA). Prefers arachidonoyl-CoA as the acyl donor. Required for primary processing step during piRNA biosynthesis. Molecular mechanisms by which it promotes piRNA biosynthesis are unclear and do not involve its acyltransferase activity.
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q14DK4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q14DK4}.
Interaction partners:
- Glycerol-3-phosphate acyltransferase 3
- Glycerol-3-phosphate acyltransferase 4
- Glycerol-3-phosphate dehydrogenase 1-like protein
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- Glycerol kinase
- Glycerol kinase 2
- Glycerol-3-phosphate acyltransferase 1, mitochondrial
- Acylglycerol kinase, mitochondrial
- 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
Sequence:
MATMLEGRCQTQPRSSPSGREASLWSSGFGMKLEAVTPFLGKYRPFVGRCCQTCTPKSWESLFHRSITDLGFCNVILVKEENTRFRGWLVRRLCYFLWSLEQHIPPCQDVPQKIMESTGVQNLLSGRVPGGTGEGQVPDLVKKEVQRILGHIQAPPRPFLVRLFSWALLRFLNCLFLNVQLHKGQMKMVQKAAQAGLPLVLLSTHKTLLDGILLPFMLLSQGLGVLRVAWDSRACSPALRALLRKLGGLFLPPEASLSLDSSEGLLARAVVQAVIEQLLVSGQPLLIFLEEPPGALGPRLSALGQAWVGFVVQAVQVGIVPDALLVPVAVTYDLVPDAPCDIDHASAPLGLWTGALAVLRSLWSRWGCSHRICSRVHLAQPFSLQEYIVSARSCWGGRQTLEQLLQPIVLGQCTAVPDTEKEQEWTPITGPLLALKEEDQLLVRRLSCHVLSASVGSSAVMSTAIMATLLLFKHQKLLGEFSWLTEEILLRGFDVGFSGQLRSLLQHSLSLLRAHVALLRIRQGDLLVVPQPGPGLTHLAQLSAELLPVFLSEAVGACAVRGLLAGRVPPQGPWELQGILLLSQNELYRQILLLMHLLPQDLLLLKPCQSSYCYCQEVLDRLIQCGLLVAEETPGSRPACDTGRQRLSRKLLWKPSGDFTDSDSDDFGEADGRYFRLSQQSHCPDFFLFLCRLLSPLLKAFAQAAAFLRQGQLPDTELGYTEQLFQFLQATAQEEGIFECADPKLAISAVWTFRDLGVLQQTPSPAGPRLHLSPTFASLDNQEKLEQFIRQFICS
Protein: Matrix metallopeptidase 17b (Matrix metalloproteinase-17b isoform 1 precursor) (A0A0R4IB00)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MMLMFWTAVVFCLWGSAVDVFGEANEDALPTSLMNMVTSTILPTAIPTEDESGKLVDWLTKYGYLPPPDPSTGQLQAWTAVTQAVKKMQSFAGLDETGILDEETLQLMQTPRCSLPDDDDDDQTIHSAQHADPQNQRMKRAVSTWTRRNINWRLRSYPVSSKLSRETIRSLVFYALRVWADPTLLEFHEVRGPEGADLQIDFLHGPHGDGYPFDGAGGSVGHAFFPSDPNRAGGVHLDAEEDWAFRQPATEGTDLFTVLVHELGHALGLTHSSARRSVMRPYYQGPLGDPLHFSLGYQDLQHITALYGQRGNDIPTETPLPVTETQLRHRHHRLTHMYRHAHSHPDSSVDRCNTSFDAVAKIRGEIFFFKGQSMWRISRGGLVSVRVVPIQRLWSALPPSLPPLRAVLERHTDHAIIFISGSQVWLFKDLSLQDGFPQPLPTLADSDGGFEGLRWDPTQGVVWGSIREEEQNEDNKVWRELIEGGVNGIIMENDHQRETNRGFKGSTYIFKGNSYWKFTHPGSAPVEGYPRLSASDWLDCPQDSSYSSADISLISQFGQQELHEQKKQTIINQIRHSEINKPQHWDCPCQNTAGTQRGHVLLLAFLLLLTVTC
Protein: TBC1 domain family member 24 (D4A3Z3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004156}. Endomembrane system {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004184}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MDSPGYNCFVDKDKMDASIQDLGPKELNYTELQELKQLARQGYWAQSHALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSSLPLPEFVDNTQVPTYCLNPRGEGAVRKILLCIANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILSCNDPGKKLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYSDWQRWLFGELPLNYFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQPLESDNVKQDIRMFVKDIAKTVSPEKLLEKAFAIRLFSRKEIQLLQMANEKALRQKGITVKQKRQFVHLAVHAENFRSEIVSVKEMRDIWSWIPERFALCQPLLLFSSLQHGYSLSRFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLSFFGTGECFVFRLQPEVQRYEWVVIKHPELTKAASFKSSEAAANPCLISHSVSSDPADRLSPFLAARHFNLPSKTESMFMAGGNDCLIIGGGGGQALYIDGDLNRGRTGHCDTFNNQPLCSESFLIAAVEAWGFQDPDTQ
Protein: Helix-loop-helix DNA-binding domain containing protein, expressed (Os03g0725800 protein) (cDNA clone:J013129F07, full insert sequence) (Q75GI1)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- Os06g0258900 protein
- Glucose-6-phosphate isomerase, cytosolic A
- Glucose-6-phosphate isomerase, cytosolic B
- phosphoglucomutase
- Fructose-bisphosphate aldolase
- phosphoglucomutase
- Fructose-bisphosphate aldolase
- fructokinase
- Glucose-6-phosphate isomerase
- Glucose-6-phosphate isomerase
Sequence:
MATQWFSNMVMDEPSFFHQWQSDGLLEQYTEQQIAVAFGQAGEADAAAAAAAMMVQQQQYAAAAAAEHRPRKAAKVNTSWDSCITEQGSPADSSSPTILSFGGHADAAAAAAFASAGQAQSAPYYGGASAAALKPKQELDAAAAPFSQARPVKRSYDAMVAADVAKAPAAAASRPASQNQEHILAERKRREKLSQRFIALSKIVPGLKKMDKASVLGDAIKYVKQLQDQVKGLEEEARRRPVEAAVLVKKSQLSADDDDGSSCDENFDGGEATAGLPEIEARVSERTVLVKIHCENRKGALITALSEVETIGLTIMNTNVLPFTSSSLDITIMATAGENFSLSVKDIVKKLNQAFKLSL
Protein: AT-hook motif nuclear-localized protein 1 (Q8VYJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs). May play a function in the positioning of chromatin fibers within the nucleus.
Subcellular location: Nucleus, nucleoplasm {ECO:0000269|PubMed:15604740}. Chromosome {ECO:0000269|PubMed:15604740}. Note=Localized specifically on the chromosomal surface region throughout mitotis. {ECO:0000269|PubMed:15604740}.
Interaction partners:
- Cytosolic sulfotransferase 11
- Probable E3 ubiquitin-protein ligase RHC1A
- AT-rich interactive domain-containing protein 5
- C2H2-like zinc finger protein
- Calponin-like domain protein
- Uncharacterized protein
- Basic leucine zipper 61
- AT-hook motif nuclear-localized protein 9
- AT-hook motif nuclear-localized protein 11
Sequence:
MVLNMESTGEAVRSTTGNDGGITVVRSDAPSDFHVAQRSESSNQSPTSVTPPPPQPSSHHTAPPPLQISTVTTTTTTAAMEGISGGLMKKKRGRPRKYGPDGTVVALSPKPISSAPAPSHLPPPSSHVIDFSASEKRSKVKPTNSFNRTKYHHQVENLGEWAPCSVGGNFTPHIITVNTGEDVTMKIISFSQQGPRSICVLSANGVISSVTLRQPDSSGGTLTYEGRFEILSLSGSFMPNDSGGTRSRTGGMSVSLASPDGRVVGGGLAGLLVAASPVQVVVGSFLAGTDHQDQKPKKNKHDFMLSSPTAAIPISSAADHRTIHSVSSLPVNNNTWQTSLASDPRNKHTDINVNVT
Protein: tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA (m6t6A37) methyltransferase) (tRNA methyltransferase O) (P28634)
Organism: Escherichia coli (strain K12)
Function: S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Thr)(GGU) that read codons starting with adenosine. The methyl group of m(6)t(6)A37 appears to slightly improve the efficiency of the tRNA decoding ability.
Interaction partners:
- Outer membrane lipoprotein RcsF
- Putative glutamine amidotransferase YafJ
- tRNA threonylcarbamoyladenosine dehydratase
Sequence:
MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAEMAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR
Protein: Kinesin-like protein KIF2A (Kinesin-2) (Q9WV63)
Organism: Rattus norvegicus (Rat)
Function: Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P28740}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:P28740}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1 (By similarity). {ECO:0000250}.
Interaction partners:
- Serine/threonine-protein kinase PLK1
- Cell division cycle protein 20 homolog
- Centromere-associated protein E
- Centrosomal protein 170
- Centrosomal protein of 170 kDa
- Kinesin-like protein
- Ninein
- Dynactin subunit 1
- Kinesin-like protein KIF2C
- Kinesin-like protein KIF2B
Sequence:
MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEDIEPSPEIPPPSSSSKVNKIVKNRRTVASIKNDPPPRDNRVVGSARARPSQLPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDCSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKELTVDPTAAGDVRPIMHHPPSQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWIEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
Protein: Zinc metalloproteinase nas-37 (EC 3.4.24.-) (Nematode astacin 37) (Q93243)
Organism: Caenorhabditis elegans
Function: Metalloprotease (By similarity). Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed. Required during ecdysis, the opening of the cuticle to allow the worm to escape.
Subcellular location: Secreted {ECO:0000269|PubMed:15539494}.
Interaction partners:
Sequence:
MKSQACLKVCLALIGLVSIVSTAYIANDVVSDYAEVKELLAAFYRKHAKKYGHDYDPAAIQAIAENMDKSVKNDKTEATVNRKLWNEVFENDIILTLPQAESLLSESNSPRSRRQAHPDPRNFWPNLTISYEFYGGEETWRQLIRSAIRHVEQNVCFKFKENGGDRDGLRYYRGNGCWSNVGRVGGRQLVSIGYGCDSLGIVSHETLHALGLWHEQSRDDRDNFISIVADKITRGTEGNFAKRTAANSDNLGQPYDLGSVMHYGAKSFAYDWSSDTIKTRDWRYQNTIGQRDGLSFKDAKMINTRYCSNVCQRSLPCLNEGYTDPNNCGRCRCPSGYGGTYCETVEYTSCGGSLTASSSYKKIESGIVQPDANCVWRIRNPGGNVEVMFDQVNFQCADPCQSYVEVKYLSQKTSTGARLCCSLPSVIRSEGDDVIIILRGTPNTAVGWRGFTLKYRAIGGTPITPATVRPTYATTTRPYWTRTASGWIHIKNPPLYKPDGQIYTSDEQSAETKYSSEELYDPSTFLSPSSSSASPALLLPSDASPQRPSAQEHDLSQLSQNALTRPTPTTTVAPDTASWSAWGEWSACSQPCGGCGTKTRVRACYGGNQVCPGSNLDRESCNAHACAKPKKGMICNGRLLLPCDLLAKLNFGSNNYLNPKLKQSGFARSSTLPLPRISQRKPVFVNELEVHPPTERFLSSSTRRVKRQTANRFCEKRFIYQCPTALLTIQMEYKPDTQGTNDAYFQQYPECCSGYTPRRGVCYKN
Protein: Serine/threonine protein phosphatase 2a regulatory subunit, putative (Q4GZ81)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
- Serine/threonine-protein phosphatase
- EF-hand domain-containing protein
- EF-hand domain-containing protein
- Uncharacterized protein
- Serine/threonine-protein phosphatase 2A activator
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
- EF-hand domain-containing protein
- Rev7, putative
- Serine/threonine-protein phosphatase
Sequence:
MSEHFKNVKSMIANLRSEDPEARLNSMRGIHVIASTLGPERTREELLPYLTDYLDENDEVLRVFANALGTMLHEVGGPAHVQSILGPLELLCSLDEVTVRDEAVSSLQTVGKALFCETGEAAVQARRDFVGLVMRLGQSTPQCRSSVTYVIATAYPHVAASVKTQLFNLFITLCGDEEIMVRRSACISLGKHMAGVPDTRSSELLNALTKFSRDASDGVRLQAVEAAAALLTVLPPETHSNIVGAVKTLVGDVSWRVRYMAADRLGKLAGVLAPPHVKQIMPFFRLLTQDSEAEIRASAVFNMAGVLAACHDATSKREVLAGGCRLVSDDNSHVRMCLASALLKSVEHVPVEMWSSTVVPTCTQLLTDTEADVRLALVSGFSSMGNTAEARELAPKLIPVVVALAEDPKWRIREVVISQIPHLITSLGRSADEVVEICVQHLVDRVAAIRDAAVQSCCSLVSESGLAWSRDTLFPRLSLMVTANNYLHRVALAHFYESLSEVQQLDRTTVSQLVLPMLRVLARDNVPNVRLRCARAIVAFKRKKILLESDAEPLLSRLVKDTDVDVRFAATEN
Protein: Mannosylglycerate synthase (MGS) (EC 2.4.1.269) (Q9RFR0)
Organism: Rhodothermus marinus (Rhodothermus obamensis)
Function: Involved in the biosynthesis of the stress protectant 2-O-alpha-D-mannosyl glycerate (MG) which is produced in response to growth at supraoptimal temperature and salinity, and protects several enzymes against inactivation by temperature, freeze-drying and osmotic stress. Catalyzes the condensation of alpha-GDP-D-mannose (GDP-Man) with D-glycerate to produce alpha-mannosyl-D-glycerate. It is specific for GDP-Man, but it can also use alpha-GDP-D-glucose (GDP-Glc), beta-GDP-D-fructose, alpha-UDP-D-mannose and alpha-UDP-D-glucose as sugar donors. It is specific for D-glycerate, but it can also use D-lactate and glycolate as sugar acceptors. This reaction occurs with a net retention of anomeric configuration; the newly formed glycosidic linkage has the same alpha configuration as the sugar donor.
Interaction partners:
Sequence:
MSLVVFPFKHEHPEVLLHNVRVAAAHPRVHEVLCIGYERDQTYEAVERAAPEISRATGTPVSVRLQERLGTLRPGKGDGMNTALRYFLEETQWERIHFYDADITSFGPDWITKAEEAADFGYGLVRHYFPRASTDAMITWMITRTGFALLWPHTELSWIEQPLGGELLMRREVAAMLYEDERVRRRSDWGIDTLYTFVTVQQGVSIYECYIPEGKAHRLYGGLDDLRTMLVECFAAIQSLQHEVVGQPAIHRQEHPHRVPVHIAERVGYDVEATLHRLMQHWTPRQVELLELFTTPVREGLRTCQRRPAFNFMDEMAWAATYHVLLEHFQPGDPDWEELLFKLWTTRVLNYTMTVALRGYDYAQQYLYRMLGRYRYQAALENGRGHPVPPRAALSTA
Protein: Protein FAM161A (Q6AY14)
Organism: Rattus norvegicus (Rat)
Function: Involved in ciliogenesis.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:22940612}. Cell projection, cilium {ECO:0000269|PubMed:22940612}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q3B820}. Note=Localized in the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium. Localizes to the inner scaffold in the central region of centrioles. {ECO:0000250|UniProtKB:Q3B820, ECO:0000269|PubMed:22940612}.
Interaction partners:
Sequence:
MWQIRASAGCHSSPGKDKEVTLENTMNFSDIYHSDEEYFRKLKDLRAAHAEAMVKLEKMYQDKLTMKDIQAALVGDDSSSSASEKSCSHPALSATSLSEPDLDRSSSLSTTTDELPDLEKKTPGEIGTRSYAKELINNMWNDFSVEDYTQYDSDLQTAKKNRKKPKAWTPRITVPVPFEMTVREQKRREKASDAQETREKMLKRNEDDAECKKKFRANPVPSRLLLPLYEDLVKQNEERRKKTRERSKAALLASQKPFKFIAREEQKQAIREKKLRELCRAKKKPKQFKARPVPRFIYRPPANVKPKREELYGDSRTQPKARDVLQSSPWPSHSTYRAFRDPRSPAMPRGKHRHRRLSPSDQGLEKWKEPFSEQSFRNCPVLCDQCCLYESLCDSNKRQKILADIRMGEEILKETRRPNPSPRHKSPRRSAHASARPCEYSPPMPTASSRGREQAIRRSEKARMKELARIGGAR
Protein: Leucine zipper transcription factor-like protein 1 (Q9NQ48)
Organism: Homo sapiens (Human)
Function: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20233871, ECO:0000269|PubMed:22072986}.
Interaction partners:
- Protein PTHB1
- BBSome complex member BBS2
- BBSome complex member BBS7
- BBSome complex member BBS4
- BBSome complex member BBS5
- BBSome complex member BBS1
- Tetratricopeptide repeat protein 8
- Sodium- and chloride-dependent transporter XTRP3
- FYVE and coiled-coil domain-containing protein 1
- Intraflagellar transport protein 27 homolog
Sequence:
MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED
Protein: Intraflagellar transport protein 52 C-terminal domain-containing protein (Osm-6 protein) (G5EDF6)
Organism: Caenorhabditis elegans
Interaction partners:
- Intraflagellar transport protein 88 homolog
- Tetratricopeptide repeat protein 30 homolog
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein osm-1
- Intraflagellar transport protein che-13
- CHE-2 protein
- Intraflagellar transport protein 56 homolog
- Intraflagellar transport protein 81 homolog
- Clusterin-associated protein 1 homolog
- TRAF3-interacting protein 1
Sequence:
MPPFSDEKMTNRSIGRKVLIDQSKQQQISLISGFRGVARHLKSVLTVEINTEPINLNGLEDVRMLIIPQPKTSFGTGEIEAIWKFVEEGGSLMILSGEGGERQSLNEMIAKYGITVNKDSVIRTVFLKYFDPKEALVANGVINRAIAVAAKKNVSTEQKHNSQALSFIYPYGCTLDVNNRMSNVVLSSGSTSFPTSRPVAAFHETKLNEMKKKGRVCVVGSVSMFHDTYIDKEENGKIFDTFVEFLVNGLELNTIDAAEPEINDYTNIPDHIHMSQQIKVCMYEGELDQAISSDFMKIMDTSLHSFNLKHWPMTIRLYEALNLSPPPLTLVEPQFELPMPPFQPAVFPPTFQELPMPPLELFDLDEQFSSPEIQLSQLANRSEEEDLIFFIEKAGEITGISAELTRSERTPKKIIELAVSKLMLFKRSMMDGELEVASAFDIGEHDAHHQSFNQGEEMDEQLFSDIDEFDDL
Protein: Protein vip1 (P87216)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MSNQVIVTNISPEVTEKQISDFFSFCGKVSNISTEKSGETQTAKIQFERPSATKTALLLQDALLGQNKIQITSEDGGAASTTDQGGAGGDQAARQEDKPRSAIISELLSRGYHLSDVTLEKSIQLDQSYGVSSKFKGILESALSGVRSVNERYHVTEKANEVDNKFAISDKLNRTSSLVSTYFHKALETAAGTSAGQKVQNAYEDGKNQLLGIHNEARRLADAKNQAEGTASPASSTPTAPAEKEPTAPTTESKTTE
Protein: Pentatricopeptide repeat-containing protein At1g62590 (Q9SXD8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Maternal effect embryo arrest 22
- E3 ubiquitin-protein ligase SGIP1
- At3g18035
Sequence:
MRISISSVVSSTTSRIVHRNLQGKGNPRIAPSSIDLCGMCYWGRAFSSGSGDYREILRNGLHDMKLDDAIGLFGGMVKSRPLPSIVEFNKLLSAIAKMKKFDVVISLGEKMQRLEIVHGLYTYNILINCFCRRSQISLALALLGKMMKLGYEPSIVTLSSLLNGYCHGKRISDAVALVDQMVEMGYRPDTITFTTLIHGLFLHNKASEAVALVDRMVQRGCQPNLVTYGVVVNGLCKRGDTDLALNLLNKMEAAKIEADVVIFNTIIDSLCKYRHVDDALNLFKEMETKGIRPNVVTYSSLISCLCSYGRWSDASQLLSDMIEKKINPNLVTFNALIDAFVKEGKFVEAEKLYDDMIKRSIDPDIFTYNSLVNGFCMHDRLDKAKQMFEFMVSKDCFPDVVTYNTLIKGFCKSKRVEDGTELFREMSHRGLVGDTVTYTTLIQGLFHDGDCDNAQKVFKQMVSDGVPPDIMTYSILLDGLCNNGKLEKALEVFDYMQKSEIKLDIYIYTTMIEGMCKAGKVDDGWDLFCSLSLKGVKPNVVTYNTMISGLCSKRLLQEAYALLKKMKEDGPLPNSGTYNTLIRAHLRDGDKAASAELIREMRSCRFVGDASTIGLVANMLHDGRLDKSFLDMLS
Protein: Vesicle transport protein SEC20 (Q8VHI8)
Organism: Rattus norvegicus (Rat)
Function: As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Also plays a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q12981}; Single-pass type IV membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q12981}; Single-pass type IV membrane protein {ECO:0000255}. Note=Localization to the mitochondrion is regulated by RNF186. {ECO:0000250|UniProtKB:Q12981}.
Interaction partners:
- Vesicle transport protein USE1
- Vesicle-trafficking protein SEC22b
- Alpha-soluble NSF attachment protein
- Syntaxin-5
- Golgi SNAP receptor complex member 2
- BET1 homolog
- Synaptosomal-associated protein 23
- Syntaxin-8
- Vesicle-associated membrane protein 7
- Syntaxin-4
Sequence:
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSELTELNTKVKEKFQQLKHRIQELEQSAKEQDKESEKQLLLQEVENHKKQMLSNQTSWRKANLTCKLAIDNLEKAELLQGGDSLRQRKTTKESLAQTSSTITESLMGISRMMSQQVQQSEEAMQTLVSSSRTLLDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL
Protein: U1 small nuclear ribonucleoprotein 70 kDa (Q6DRE8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Small nuclear ribonucleoprotein Sm D2
- U1 small nuclear ribonucleoprotein A
- U1 small nuclear ribonucleoprotein C
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein Sm D3
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein polypeptide F.
- Splicing factor 3B subunit 1
- Splicing factor 3A subunit 2
Sequence:
MTQFLPPNLLALFAPRDPIPFLPQLGKLPHEKHHNQPYCGIAPFIRHFEDPRDAPPPTRAETREERLERKRREKMERRQVVVEGELKLWDPHNDANAQGDAFKTLFVARINYDTTESKLRREFEVYGPIKRIYIVYNKKTGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIKHSGRDDTSRYDDRPIGSDRDRDRGERRERSRERDRDKERGERRRSRSRERRRHTRSHERERAAAGDEAGGSSRRRERERERGGAGAGESRERSRDRDRDRDRKRRSRSRDRKRDRERGKGAEGGEEGMGGLVDGMMPEGGDRGIEDPLGGEPGRGEEGGPEGEERGRDRDKDRERDRDRKRSHRDKDRERDRDRRRDRDRDRDHKRDRGDRDRGERREDRHITSSGDHEGLGNGGEEGEEPVPPQSEEGSQDGMRMMMMDQDSMQSGEGYASNENGYRMEAQGDEY
Protein: Putative glutathione S-transferase C1183.02 (EC 2.5.1.18) (O74830)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the oxidative stress response and detoxification.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Elongation factor 1-beta
- Uncharacterized sulfatase PB10D8.02c
- Elongation factor 2
- Elongation factor 1-alpha-B/C
- Elongation factor 1-alpha-A
- Elongation factor 1-alpha-B
- Zinc-type alcohol dehydrogenase-like protein C1773.06c
- mRNA export factor elf1
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein uS5
Sequence:
MFLGTLYSFKTNTRTVCLLELAKLLDLQVDLVETYPHKFSADLAAKFPLQKLPVFIGADGFELSEVIAIVKYFYEKGKHNDKEGLGPVNEVEEAEMLKWMCFINFDIVTPQNVRPWVGMFRGNIPYEEKPFKESATRAIDSLKIPNELVKDRTYLVGDRFTLADLFFGSLLRIFFNSIIDEKTRKELPHLTRYYITMFHQAKLETYFPLELPLTVTVAKK