wanglab/gogpt-training-data huggingface dataset:
Protein: Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase (EC 3.4.-.-) (EC 3.4.17.13) (Lipoprotein Spr) (Murein hydrolase MepS) (P0AFV4)
Organism: Escherichia coli (strain K12)
Function: A murein DD-endopeptidase with specificity for D-Ala-meso-diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Also has weak LD-carboxypeptidase activity on L-mDAP-D-Ala peptide bonds. Partially suppresses a prc disruption mutant.
Subcellular location: Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
- Murein DD-endopeptidase MepM
- Lipoprotein NlpI
- Tail-specific protease
- Penicillin-binding protein 1B
- D-alanyl-D-alanine endopeptidase
- Endolytic murein transglycosylase
- D-alanyl-D-alanine carboxypeptidase DacB
- Penicillin-binding protein 1A
- D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH
- Penicillin-binding protein activator LpoB
Sequence:
MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVGSETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTFREQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHASTSSGVIISSMNEPYWKKRYNEARRVLSRS
Protein: Retinoic acid receptor gamma-B (RAR-gamma-B) (Nuclear receptor subfamily 1 group B member 3-B) (A2T928)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity). Required for hindbrain development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- Arginyl-tRNA synthetase
Sequence:
MRDVFREATPMTCRSPLPDLRDMMEKLTVFEPTIDSTVETQSTSSEEMIPSSPSPPPPPRVYKPCFVCQDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCQINKVTRNRCQYCRLRKCFEVGMSKEAVRNDRNKKKKDVKEEVVLPESYELSGELEELVNKVSKAHRETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELSTKCIIKIVEFAKRLPGFTSLTIADQITLLKSACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPHRVDQLQEPLLEALKIYARRRRPNKPHMFPRMLMKVTDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEIFEDSSDSNDSGAAAVVPAPNIKRMGQRQAAWVKGERPEWVRGRRRGSKSRYKAGFKAGKARSRDSPDNNGEIRQGDERSEMSVRAEQDFALE
Protein: Galectin (Q6TGN5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAGVLIQNMSFKVGQTLTITGVPKPDSTNFAINIGHSPEDIALHMNPRFDAHGDQCTIVCNSFQSGSWCEEHRDDNFPFIQDKEFQIKITFTNEEFLVTLPDGSEIHFPNRQGSEKYKYMYFEGEVRIQGVEIK
Protein: RNA helicase (EC 3.6.4.13) (Q9TY94)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- RNA and export factor binding protein, putative
- THO complex subunit 2, putative
- SAP domain-containing protein, putative
- RNA helicase
- RNA-binding protein 8A, putative
- Mago nashi protein homologue, putative
- Peptidyl-tRNA hydrolase ICT1
- Peptidyl-tRNA hydrolase ICT1
- Nuclear polyadenylated RNA-binding protein NAB2, putative
- RNA helicase
Sequence:
MASMDHNAQDELVDYEDDENILDSKDVKGNLGNNILNNNNKGGAMRGSYATVHTGGFKDFFLKPELLRAISESGFEHPSEVQQETIPAAITGTDILCQAKSGMGKTAVFVLSILQQLDTNENQDMQDTKEMNNDNNNNGDNKFVRCLGLAHTRELAYQIKNEFDRFSKYLKNVRCEVVYGGISMNKHIKLFKEDNIPHIIIGTPGRILALIREKYLITDKIQHFVLDECDKCLEKLDMRSDVQKIFISTPLKKQVMFFSATMAKEMRDVCKKFLQNPVEIFIDDEAKLKLHGLLQHYVKLQEKDKTRKLIEILDALEFNQVIIFVKSVTRAITLDKLLTECNFPSIAIHGGLEQQERIERYDKFKKFENRILVSTDLFGRGIDIERVNIVINYDMPENSDSYLHRVGRAGRFGTKGLAVTFVSSQEDTLALNEVQTRFEVAISEMPNKIDCNEYINQ
Protein: F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (B1H1X1)
Organism: Xenopus laevis (African clawed frog)
Function: Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteasome (By similarity). The ability of the SCF(FBXL17) complex to eliminate compromised BTB dimers is required for the differentiation and survival of neural crest and neuronal cells.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9UF56}. Nucleus {ECO:0000250|UniProtKB:Q9UF56}. Note=Present in the cytoplasm and nucleus; more abundant in the cytoplasm. {ECO:0000250|UniProtKB:Q9UF56}.
Interaction partners:
- Uncharacterized protein
- Cullin-1
- S-phase kinase-associated protein 1
- CULLIN_2 domain-containing protein
- Protein prenyltransferase alpha subunit repeat-containing protein 1-B
- Uncharacterized protein.
- Geranylgeranyl transferase type-2 subunit beta
- BZIP domain-containing protein.
- transcription regulator protein BACH1
- E3 ubiquitin-protein ligase RBX1
Sequence:
MGHVAPHASKKEHVAPHAAEKDHVAPHASKKEHVAPHAAEKGQVAPYAAGEGQVAPNAAGERPVAPYAAGEGQVAPYAAGEGQVAPYAAGEGQVAPYAAGEGQVAPYAAGEAQVAPHAAGEGRVAPHAAGDGQVEHCTVEDREEGHIGTTEQGHMSHYTSKLEHMAPPSAQTEAVVSYVAGERHAPPDCTVSGPAMCCSAEARQTTPDWTTTGPEISQGTLPGLTVLHVGGTWQTFAAEDEPCVTTLLSPVKPLSSSRKYAPYNLQIPSYSESEPQAHKGLSSETFGPCEPLHINQLPSSLLLKIFSNLSLNERCILASLVCKYWRDLCLDSQFWKQLDLSNRQQIKDNILEEIASRSQNITEINISDCFSVSDQGVCVVALKCPGLVKYTAYRCKQLSDISLIALAAHCPSLQKVHVGNQDKLSDEALIQMGRRCKELKDIHFGQCYKISDEGLIVIAKGCQKLQKIYMQENKLVSDESVKAFAEHCPGLQYVGFMGCSVTSEGVINLTKLKHLSSLDLRHITELDNETVMEIVKQCQHLTSLNLCLNRSINDRCVEVIAKEGRSLKELYLVTCKITDYALIAIGRYSKSIETVDVGWCKEITDYGAKQIAQSSKSIRYLGLMRCDKVNEATVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNASPAT
Protein: Protein WFDC10B (Q8IUB3)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- WAP four-disulfide core domain protein 3
Sequence:
MAPQTLLLVLVLCVLLLQAQGGYRDKMRMQRIKVCEKRPSIDLCIHHCSYFQKCETNKICCSAFCGNICMSIL
Protein: SMP-LTD domain-containing protein (Q54YE5)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MSLKIYWDRVTEKHSIKLMNYLNERISGLTETYDMVGEMKITNLSLGSKPPKFEIIQISDPDALILGNKSPNGIELRAKIGYDGDAYIGIQAEFKVNLPTPNFISFPVNVKVSNPIFSGIATVIYDTDKVCFCFLPENGDSPDDFTPLKDVKFETQLGDSAQQVLVDLDKLQNFIVDLIKTYLKKYLVFPNKMTIPLSEFNN
Protein: Zinc finger protein ENHYDROUS (Protein indeterminate-domain 1) (Q9LVQ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor promoting the transition to germination by regulating light and hormonal signaling during seed maturation. Acts as a positive regulator of phytochrome and/or gibberellin action.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:21571950}.
Interaction partners:
- Protein LOW PSII ACCUMULATION 1
- Zinc finger protein AZF3
- Glyoxylate/hydroxypyruvate reductase HPR3
- DELLA protein GAI
Sequence:
MPVDLDNSSTVSGDASVSSTGNQNLTPKSVGKKKRNLPGMPDPDAEVIALSPKTLMATNRFVCEICNKGFQRDQNLQLHRRGHNLPWKLRQRSTKEVRKKVYVCPVSGCVHHDPSRALGDLTGIKKHFCRKHGEKKWKCEKCSKKYAVQSDWKAHSKICGTKEYKCDCGTLFSRRDSFITHRAFCDALAEESAKNHTQSKKLYPETVTRKNPEIEQKSPAAVESSPSLPPSSPPSVAIAPAPAISVETESVKIISSSVLPIQNSPESQENNNHPEVIIEEASRTIGFNVSSSDLSNDHSNNNGGYAGLFVSSTASPSLYASSTASPSLFAPSSSMEPISLCLSTNPSLFGPTIRDPPHFLTPLPPQPAMSATALLQKAAQMGSTGSGGSLLRGLGIVSTTSSSMELSNHDALSLAPGLGLGLPCSSGGSGSGLKELMMGNSSVFGPKQTTLDFLGLGRAVGNGGNTGGGLSALLTSIGGGGGIDLFGSGEFSGKDIGRSS
Protein: LexA repressor 2 (EC 3.4.21.88) (P60511)
Organism: Xanthomonas axonopodis pv. citri (strain 306)
Function: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Interaction partners:
Sequence:
MDLTDTQQAILALIAERIDADGVPPSQTEIARAFGFKGIRAAQYHLEALEHAGAIRRVPGQARGIRLAGQGAQTRTAPVSEVARDDVLRLPVLGRVAAGLPIGADIGSDDFVVLDRVFFSPSPDYLLKVQGDSMRDEGIFNGDLIGVHRTRDARSGQIVVARIDEEITVKLLKIGKDRIRLLPRNPDYAPIEVLPDQDFAIEGLYCGLLRPNR
Protein: Calcium uptake protein 3, mitochondrial (hMICU3) (EF-hand domain-containing family member A2) (Q86XE3)
Organism: Homo sapiens (Human)
Function: May play a role in mitochondrial calcium uptake.
Subcellular location: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:Q8IYU8}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q8IYU8}. Note=Recruited to the mitochondrial inner membrane via its association with the uniplex complex. {ECO:0000250|UniProtKB:Q8IYU8}.
Interaction partners:
- Essential MCU regulator, mitochondrial
- Calcium uptake protein 1, mitochondrial
- Calcium uniporter regulatory subunit MCUb, mitochondrial
- Mitochondrial calcium uniporter regulator 1
- Calcium uptake protein 2, mitochondrial
- Calcium uniporter protein, mitochondrial
- Fibroblast growth factor 20
- Fibroblast growth factor 9
- Mitochondrial adenyl nucleotide antiporter SLC25A23
Sequence:
MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIPVAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR
Protein: Carnosine N-methyltransferase (EC 2.1.1.22) (Q9Y7J3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MEYDEEEVKVLKEVLSAFFLYRQYAHTITQQKRKSMSRLSFEHKDLLLQDSDNNFLKHLSRIDQCIEQNSVLAEAIANAAIPVFCSDFDQNELFHVNVDMMQKVSSTLKQIARDWSTECVEERRTTYAPFIEELNSLFPSDSIDRSKIRVLVPGSGLGRLAFDIAVEGFACQGNEFSYFMLLTSHFILNCVKQENQFLVYPYIHSFSNHVMRDDQVRSLNIPDAVPSQYLRNSQNFSMAAGDFLEVYGTEESRDSFQVVATCFFIDTTKNILDYLDTIKNCLVDGGYWINLGPLLYHFESEGTSNSNSDSQQQPFVELTLEQLFYVMDSMGFEVLKHNSVDTTYMGDKRSMLEWIYHPHYWVCRLQKSKLRFQ
Protein: Molybdenum storage protein subunit beta (Mo storage protein subunit beta) (MoSto subunit beta) (P84253)
Organism: Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Function: Intracellular storage of molybdenum. Binds polyoxomolybdates. Can bind at least 90 molybdenum atoms per protein molecule.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15651045}.
Interaction partners:
- Molybdenum storage protein subunit alpha
- Ribosome-recycling factor
- Elongation factor Ts
- Small ribosomal subunit protein uS2
- Uridylate kinase
- Phenylalanine--tRNA ligase beta subunit
Sequence:
MANSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS
Protein: CHE-14 protein (SSD domain-containing protein) (G5EEW0)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- SSD domain-containing protein
- Warthog protein 1
- Warthog protein 8
- Rootletin
Sequence:
MIERVGRLYSRSLYRHPTLFLILPVLITTVIPFGLIWFFPIKLSQNAEIGFDTKDTDLSGPRLAWSRIQPSLMFSNRIAFSNPRPIDTDVQQPSAHPVSTKRNKRSWADNLLSAINQVACYDSPIPLMDHLSQFILEVPNYDAIFNLKFLDKLCQMQSNISKPLSRFDAFTPYRNIWSVANMFACISPNLRVNCTELDESDIKIVRKTIDNCWKYRTQIFECRDEKCQGQCATCRELPENCSSQIMYDLFYRLLPKQRDDTPFLVNTFLPVFTLTGYITQNIPVNVIIYDDLETSIIDYSKKNKFHLKGLLMDVKRDRLLAAALRDSMLALLAAGLVMIVVAVHSQSLLYAFVVILLLALSVVGALGVYSLFTDEFPLLNLVTFVLLIAIGSDDAFLLKSNFPKHLNEDTFHTFLSHTSFTMFLTCFSTIVPFFINITSNVIVFRCFGLFAGVTVIFNYFMVVSFLPAFLLIQYRHFDCFTGFKFPYRSVLSHLLYVLLPHVLVQGRYVLISLLSIVAIGGAAITYQGLHLPEYNPLQLFTSDNLHEWYDNNAERNFEFVSAKIALPLTSRLVWGVEPIYSLSTFRANATSPLRSDPIFSLKTAGDVRKLARFLGTARQLPFVNHQPKFWPERFLDWSDKYPCARGFLCCNMTNPLFSDSYLDFCLRNSTSFLATSYNDTPIFDNKTFAFVGYTAMLPTSLKYNHRFKQLSKSFEMLEMTKPDNGWWAPEWWLMSTWFDLLSSIVQDCLSSVVGSLVFVAIFAFIQLKFQAFAAVVTIACVIFTSSAIVTLLGWVLGVLEAVILVLVVGLSFDYTLHYGAALPEHGCAEHRIREATSKGVGPVTLAAFTSFLAGASMLPALTHAFYQVGVFLVVISITSWTFSTFFYLPMLSLTLPNQSGICPYCEKTNLMHLSPRS
Protein: Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2) (Q5T0F9)
Organism: Homo sapiens (Human)
Function: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells.
Subcellular location: Nucleus {ECO:0000269|PubMed:19423080}.
Interaction partners:
- Charged multivesicular body protein 4b
- Charged multivesicular body protein 4c
- Charged multivesicular body protein 4a
- Charged multivesicular body protein 7
- Charged multivesicular body protein 6
- IST1 homolog
Sequence:
MMPGPRPRKGPQARGQGVAAAKQMGLFMEFGPEDMLLGMDEAEDDEDLEAELLALTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDRKKQLEILQLAQAQGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFDQLFKLNINRNHRGFKRVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSGQDVQMVTENWLVLEPRGL
Protein: Chromatin licensing and DNA replication factor 1 (DNA replication factor Cdt1 isoform X1) (E7F2R5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Origin recognition complex, subunit 2.
- Cell division control protein
- Geminin DNA replication inhibitor.
- Origin recognition complex subunit 5
- DNA helicase
- Origin recognition complex subunit 1
- Origin recognition complex subunit 4
- Origin recognition complex subunit 3
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM7
Sequence:
MAQARVTDYFAQSKKAGVSRSLRSKGQKVSGDVVESAVINKPRSSSRASGSSRKATHSEITTAEPQKQTQLEFLKVIDEALSTETAETVADSRDVNIEGLTASPRTPKRSSPEFDVCSVLFPSTAELHSSAKKRQRLNAGHNCRSSPEERTGQKTARKKLNLLASDDKVKSTEPLASSSPQAPQQTARKESKNTVNHIANTSTVNKPNGDENPQRATRSKKTFSREDVAALKSKLQKLKGQSENVSTPSPGPVSTLTELKARLDAAREISAKVQQRKAERVIEEAKAAETQPATEPQEREKLPAYQRYHTLAQDVPPGLTLPYQYKLLAEMFRSLETIVAMLFNRSETVTFTKVKQGVQDMMRKRFEESHLGQIKAVYPSAYTFRQEKNIISFSATAKRSSYQLTVEPVIDEEFKGVRPVLSASRLLERRHIFHQNLVEIVKGHHKTFLASLNPPIVVPDEKLTRWHPRFSVDEVPNVKPSDLPQPPQTEKLTSAQEVLDKARALMTPKMEKALANMALKTAEKACVKEPETTAKSAVTPTETPGALKGVSQSLLERIRAKEAQKLHAVMTRNPQQEERLLMMSRLPELARILRNVFVAEKKPALIMELACNRMIASYRSPLTSDEMEKHLRLLAELTPAWLTIHPIRKDLYLKLNKTTDLSIVLDKLNQKTKEEERI
Protein: Dof zinc finger protein DOF5.1 (AtDOF5.1) (Protein PHLOEM EARLY DOF 2) (Q9LZ56)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Binds to 5'-TAAAGT-3' motif in REV promoter to triggers its transcription, thus regulating adaxial-abaxial polarity and influencing leaf axial patterning in an auxin transport- and response-dependent manner (e.g. IAA6 and IAA19 genes expression). Probably involved in early processes for vascular development. The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00071, ECO:0000269|PubMed:20807212}.
Interaction partners:
- F12P19.8 protein
Sequence:
MVFSSFPTYPDHSSNWQQQHQPITTTVGFTGNNINQQFLPHHPLPPQQQQTPPQLHHNNGNGGVAVPGGPGGLIRPGSMAERARLANIPLPETALKCPRCDSTNTKFCYFNNYSLTQPRHFCKACRRYWTRGGALRSVPVGGGCRRNKRTKNSSGGGGGSTSSGNSKSQDSATSNDQYHHRAMANNQMGPPSSSSSLSSLLSSYNAGLIPGHDHNSNNNNILGLGSSLPPLKLMPPLDFTDNFTLQYGAVSAPSYHIGGGSSGGAAALLNGFDQWRFPATNQLPLGGLDPFDQQHQMEQQNPGYGLVTGSGQYRPKNIFHNLISSSSSASSAMVTATASQLASVKMEDSNNQLNLSRQLFGDEQQLWNIHGAAAASTAAATSSWSEVSNNFSSSSTSNI
Protein: Protein RESTRICTED TEV MOVEMENT 3 (Protein RTM3) (MATH domain and coiled-coil domain-containing protein RTM3) (Restricted tobacco etch virus movement protein 3) (D5K228)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the restriction of long-distance movement of the pathogenic tobacco etch virus (TEV) without causing a hypersensitive response or inducing systemic acquired resistance.
Interaction partners:
- Protein RESTRICTED TEV MOVEMENT 1
- Protein RESTRICTED TEV MOVEMENT 2
- HSP20-like chaperones superfamily protein
- At2g27140
- Jacalin-related lectin 2
- Jacalin-related lectin 15
- Heavy metal-associated isoprenylated plant protein 43
- Heavy metal-associated isoprenylated plant protein 33
- Disease resistance-like protein DSC2
- Eukaryotic translation initiation factor 3 subunit B
Sequence:
MGKQFDKKITWTIKNFASLLSDLIYSDHFVVGGCKWHLRAYPKGYNNANSLSLFLGVAVPTSLPSGWRRHTKFRLTLVNQLSDKLSQSKLNELEQWFDEKTTNWGLSSMCPLNEIHAKDSGFLLNGELKIVVEIKVLETIGKLDVTEETSTITETVDVNGFQLLPSQAKSVSRMFAKHPELASDLRPKNPNLRTGYMSLLLSLIETLSQLPQQMSKDDLLDAYDALGSMRDAGFKLDWLEKKLYEVSEKKENEEASETGLQEMEEELKDMKQKCLEMEALVEKEKAKVSTAKAPISFDDIV
Protein: Fanconi anemia group D2 protein (F4JIJ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Fanconi anemia group I-like protein
- AT5G65740 protein
- Fanconi-associated nuclease 1 homolog
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B
- Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A
- ARM repeat superfamily protein
- Probable ubiquitin-conjugating enzyme E2 37
- Serine/threonine-protein kinase ATR
- AT5G12460.1
- Fanconi anemia group E protein FANCE protein
Sequence:
MVFLSRKKPPPPPSSSSAAPSLKIPQPQKESVEPDAVEKMTAILAEVGCTLMNPYGPPCLPSDLHAFRRNLTGRLSSFSANSGERDNVGALCSVFVAGFSLYIQSPSNLRRMLSSSSTTKRDESLVRNLLLVSPIQLDIQEMLLEKLPEYFDVVTGCSLEEDVARLIINHFRWLDFIVNPHVFTDKLMQVLSICPLHLKKEIIGSLPEIIGDHNCQAVVDSLEKMLQEDSAVVVAVLDSFSNLNLDDQLQEQAITVAISCIRTIDGEHMPYLLRFLLLAATPVNVRRIISQIREQLKFTGMSQPCASQNKLKGKVPAYNAEGSILHALRSSLRFKNILCQEIIKELNSLEKPRDFKVIDVWLLILMYMNGDPVRKSIEKIFKKKVVDECIQEALLDQCIGGNKEFVKDNFASFVSLAEHLLSSKEEKAREIGSHIYSRLFEEFTDNYSRQEILGALVTHVGSDNKFEVSSVLEMMTALVKKYAQQLLPFSSHINGILDYLEGFTIDNLHKVYEVFSLLALSARASGDSFRSSISNELMMIVRKQVSHPDLKYKKMGLVGSLRIVSSLGDAKSVPDFSSSQVSDCGEILELLKTSVESCRQSNLALIMFYDEFATILSHKLLQPEIMEWIGKHLGEFESLFLADLENEKMAEKGSYSGLEGDLWMNLDGSISPICLNILALASSSSESCCLQILPSNFLLLSTVERLTNDGSLAGVDALLGCPLHLPSSKYFAAAGWQSLAKKQKEILSLSLYYAANWIRELLNAFSSQIDEKIGCISQATVKDVTTKLLKRLRNLVFLESLLSNLITLSPQSLPELHPYSESHVEHPRKKNEKRKLDDDASQRKVSMKNNLKKSKHSDVNEKLRQPTIMDAFKKAGAVMSHSQTQLRGTPSLPSMDGSTAAGSMDENCSDNESLIVKIPQVSSALEAQRFKFRPLLPQCLSILNFPKVLSQDMGSPEYRAELPLYLYLLHDLHTKLDCLVPPGKQHPFKRGSAPGYFGRFKLVELLNQIKRLFPSLRIHLNIAISLLIRGDETSQTTWRDEFALSGNPNTSSIVVSESLVYTMVCKEVLYCFSKILTLPEFETDKSLLLNLLEAFQPTEIPVANFPDFQPFPSPGTKEYLYIGVSYFFEDILNKGNYFCSFTDDFPYPCSFSFDLAFECLLTLQLVVTSVQKYLGKVSEEANRKRNPGHFHGLVPNLHAKLGTSAEKLLRHKWVDESTDNKGLKNKVCPFVSNLRIVQFTGEMVQTILRIYLEASGSTSDLLDELACTILPQASLSKSTGEDDDARDHEFPTLCAATFRGWYKTLLEENLAILNKLVKTVSSEKRQNCQPKTTEAHLKNIQKTVNVVVSLVNLCRSHEKVTIHGMAIKYGGKYVDSFLKVFDFLEAHFQDHKELVIQLGMKQTAITSKIPATKRSLERFLFHVKALLHRTSGGSNFWMGSLKHKDLRGQIVSSQAYIDNEADEVEETMSGEEEPMQEDELPLTP
Protein: Quorum-sensing control repressor (G3XD77)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Acyl-homoserine-lactone synthase
- Acyl-homoserine-lactone synthase
- Fatty acid hydroxylase domain-containing protein
- ATP-dependent RNA helicase RhlB
- Regulatory protein RsaL
- cAMP-activated global transcriptional regulator Vfr
- Quorum threshold expression element, QteE
- N-acetyltransferase domain-containing protein
- histidine kinase
- Multiple virulence factor regulator MvfR
Sequence:
MHDEREGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPGEWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN
Protein: Branchpoint-bridging protein (Q9U1J9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU367126}.
Interaction partners:
Sequence:
MSATPPDLLSLAASREVSAAVAVAASANGGSGRSADKERSRSRDRGRDKDKDRDKDRKKRDKDSRDRDSRRRDDRGDRDRDRERDRDSRSHRSKSRNYDDGDRRRKRSRSRDRDRDRKRDRDRDSRSRRSSSRGGRDDYDRSRRRRSRSRSYERRRNDRGSQRDQRDQPSQRSSRERTHVNPFDTSNSRNSLNQDHDQSRIPSLFDRQQGLETIREEGREQRFDLTQTIQELMGNAGGNKGFASFFNSQNSNDSTSNGAFDNSADSAAERKRKRKSRWGGSENDKTFIPGMPTILPSTLDPAQQEAYLVQFQIEEISRKLRTGDLGITQNPEERSPSPEPIYSSDGKRLNTREFRYRKRLEEQRHQLIVKMQTVNPEFKPPADYKPPVTRVSDKVLIPQEQHPDINFVGLLIGPRGNTLKAMEKDTGAKIIIRGKGSVKEGKVGRKDGQPLPGEDEPLHAFITAPNPEAVRKAVDKIKDVIRQGIEVPEGHNDLRRMQLRELAQLNGTLRENDIQRCTCGSTDHKSWQCPDKPIITNTIVCTSCGGTGHLTKDCRNKRPGSGVPGMACEDSQAKIDEEYMSLMAELGEGPPPPSASAKTDPPASNGPQLHRASYSIFDKKPSQMQAIQSPPSSSSRDHQRDLGGWGAAAHEHGMGMEHGMGLDQHGHGLAAMDHGMSLGMEHAMAAYVPAPPGTQAPPPMPPPLMPWMSAPQPPPPATEPLNPPIPGTLPPLIPPPPGTSARPCRRGVEALTVAGAAAMRRLHLRPAHRRHQP
Protein: Ferroportin (Ferroportin-1) (Iron-regulated transporter 1) (Metal transporter protein 1) (MTP1) (Solute carrier family 40 member 1) (Q9JHI9)
Organism: Mus musculus (Mouse)
Function: Major iron transporter that plays a key role in balancing cellular and systemic iron levels. Transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues. Controls therefore dietary iron uptake, iron recycling by macrophages, and release of iron stores in hepatocytes. When iron is in excess hepcidin/HAMP levels increase, resulting in a degradation of ferroportin/SLC40A1 limiting the iron efflux to plasma (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9NP59}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9NP59}. Basolateral cell membrane {ECO:0000269|PubMed:10693807}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9NP59}. Note=Localized to the basolateral membrane of polarized epithelial cells. {ECO:0000269|PubMed:10693807}.
Interaction partners:
- Hepcidin-2
- Hepcidin
- Hephaestin
- Ceruloplasmin
- Natural resistance-associated macrophage protein 2
- Transferrin receptor protein 1
- Plasma membrane ascorbate-dependent reductase CYBRD1
- Transferrin receptor protein 2
- Ferritin light chain 1
- Ferritin heavy chain
Sequence:
MTKARDQTHQEGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKNELLTMYHGWVLTVCYILIITIANIANLASTATAITIQRDWIVVVAGENRSRLADMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAALKVEESELKQLTSPKDTEPKPLEGTHLMGEKDSNIRELECEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLFSGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFVNVEPVSPTTKIPETVFTTEMHMSNMSNVHEMSTKPIPIVSVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHLMYFRFAQKTLGNQIFVCGPDEKEVTDENQPNTSVV
Protein: Transient receptor potential cation channel, subfamily C, member 6 (F7EUD8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MSQSPGFVTRRGGSPKAAPGAGARRNESQDYLLMDELGDDGYPQLQQPPYGYYPSFRGNENRLTHRRQTVLREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECLSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFVVGLLDLCRNTEEVEAILNGDAETRQPGDLARPNLSRLKLAIKYEVKKVRSGVRPLHVFSLCEWICTVGSRGLSQGSIQ
Protein: Uncharacterized protein At4g14450, chloroplastic (Q6NN02)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Mitogen-activated protein kinase 11
Sequence:
MFFDTKVLNYPTIHKSISMASTMQRTSSSAASNERQLSQLQRRAPSLMIKPTSFSNWNVAIPLLSPLAPSLTSSFDQSHVPPPQNKTEIPVEEEVKKTPVFKKWQHPASPFCYEPTTFVPPFIQV