wanglab/gogpt-training-data huggingface dataset:
Protein: Swi5-dependent recombination DNA repair protein 1 (DNA repair protein dds20) (Meiotically up-regulated gene 13 protein) (Q9USV1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in DNA recombination repair and meiotic chromosome segregation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Mating-type switching protein swi5
- DNA repair protein rhp55
- DNA repair protein rhp57
- DNA repair protein rhp51
- Meiotic recombination protein dmc1
- DNA repair protein rlp1
- ATP-dependent DNA helicase fml1
- DNA repair protein rdl1
- Zinc finger SWIM domain-containing protein sws1
- ATP-dependent DNA helicase hus2/rqh1
Sequence:
MSQTINSELNENATSQCKEDLKVSLSESDLRDSQGQLGIENPPKCNNSGNHSDNLGFIEQSETVHPENEKALTPDLRDTKIHTSLPITTPFSKKRAREAKNILLKPFKSPLRQTASPQVADTNLKPSLAVTNLNSDETNTSSEPVTSPLRTTPNSIKRQKRLFKSPISNCLNPKSDPEITQLLSRRLKLEKEVRNLQEQLITAETARKVEAKNEDKDLQTLIQKWKNAAQQAAEVLFKPMAERIRLAGGVTQSFRIEEGENKGQIQEVRTEFTMSMFLNQFGVPVHLMSFDEENGDWKS
Protein: Potassium/proton antiporter CemA (Chloroplast envelope membrane protein A) (CemA) (P12212)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000255|HAMAP-Rule:MF_01308}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01308}.
Interaction partners:
- Photosystem I assembly protein Ycf4
- Photosystem II reaction center protein Z
- Cytochrome c biogenesis protein CcsA
- Photosystem I reaction center subunit VIII
- ATP synthase subunit b, chloroplastic
- Large ribosomal subunit protein bL33c
- Photosystem II reaction center protein K
- Photosystem II reaction center protein H
- Photosystem I reaction center subunit IX
- Cytochrome b559 subunit alpha
Sequence:
MKKKKALPSFLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSQTLLTAIQEKRVLERFMELEDLFILDEMIKEKPNTHVQNPPIGIRKEIIQLAKIDNEGHLHIILHFSTNIICLAILSGSFFLGKEELVILNSWVQEFFYNLNDSVKAFFILLVTDFFVGFHSTRGWELLIRWVYNDLGWVPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
Protein: Uncharacterized protein (Q38EJ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNQPTTTHKTPYCQTKVQTQANPRSGPAARRPQHRQSRSLAAASKGKQGRAGNSAPKSTQKRAATRASRGNPLDISKSTEISTSDTSAAVCLASPPYCESAAVSKERSNVPLTPTRRLNSLQQLKPDDLSSSAKEVKETEEAAPASSLSASAFSTLLSPTQILQATGLHGGITTQSVTSGPGSGDDREVLRTEMSRKGLSVHAAPFLPLSRTAPQSPALAQATCEHGVPLFPCEGSKRYIDSIVSPCSVEDVRAQSHSLEFPCTPLVLRGGMVYHPPGFRGGGALATSESCLSPDTPKVGSTSSIIPASVKPVTSSPTFDTLRCQQCVQCGDGKDDSVEDIPYTTEGVEDSCEGDGIRHLRIPFTDAEAQDEAKMLHMLQMGEEEEDAASVGQEWQECIFGSSNAGASNVELFHCAGGYWDVNGPSVATRRLLRHRMPSSSSLNIDAQGDEFSSVLASQSEYSADHGHFAYDNDDGSWEMSSSAYADSLDDEQLEWIEQHLRAK
Protein: Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase) (P47245)
Organism: Rattus norvegicus (Rat)
Function: Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs. Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination. Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH) (By similarity).
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:O43847}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8BHG1}.
Interaction partners:
- Proheparin-binding EGF-like growth factor
Sequence:
MLRRVAVAAVFATGRKLRCEAGRDVTAVGRIEARGLCEESAKPFPTLTMPGRNKAKSTCSCPDLQPNGQDLGESGRVARLGADESEEEGRSLSNVGDPEIIKSPSDPKQYRYIKLQNGLQALLISDLSNVEGKTGNATDEEEEEEEEEEEGEEEEEEEEDDDDDDDEDSGAEIQDDDEEGFDDEEEFDDDEHDDDDLDNEENELEELEERVEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPKPNFSHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRVFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPEVIAEALNQLVPQKANLVLLSGANEGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNSDLHLPAENKYIATDFTLKAFDCPETEYPAKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEFSSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYSRWSMIDKYRALMDGLSLESLLNFVKDFKSQLFVEGLVQGNVTSTESMDFLRYVVDKLNFVPLEREMPVQFQVVELPSGHHLCKVRALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSETVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVSWFKAHRGPGSKMLSVHVVGYGKYELEEDGAPVCEDPNSREGMQLIYLPPSPLLAESTTPITDIRAFTATLSLFPYHKIVK
Protein: Motility regulator (Q9HVI8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable transcriptional regulator
- Diguanylate cyclase
- EAL domain-containing protein
- Cyclic di-GMP phosphodiesterase PA2567
- histidine kinase
- histidine kinase
- histidine kinase
- FimX
- histidine kinase
- Sensory/regulatory protein RpfC
Sequence:
MSTPSLTPSPPPAGDPLTVPDRPAAKAGLLLLVLLMLGLLLWQMSQELRQQERFEHERAAAQLDRLNDRLSLTLELKARTALALLPGVPPSERGEIQGRLLPRISDALPQVRQLQWVDSAPQTDSPSPETTLPEQLRQHAGSGLYHYCLDPRDGESLYLTLREPGSRRDSGFWLLHLASDSLAQWSPDLPTGNLLWRLEDQYAGRVLWHTPGSTALLDDMQTLGVEPLRNSDWQLRGLYDSTRVRLGLLPGIGGELAIFLLLVGVTVYMLLRLHREQQGLRAMTLASQRSLRQAATALAAIDERVLVTRADGRLSYLNPQAERLFGISSAQARQHHLLGLLPDLEPGWLTDAGGDGETRSELLPLRVRGEPRTFTLSRHPLASYPALADQAWTLREQILQGGQVWVLRDVTEEQHALGVLEETRRRYQDIFEGVGVALCVLDLSALRQALVEQGLDSCAALRAWLAGEPGRQQALLERIRITEINDVSRRLLQIDSTEQAWQRLLDHGPLQPDSLRLQVIEALIERRPVLELEATLRCGKSTPRHLWLQLRLPENPGEWHAVTLSLSDVTSRKEVELSLIEREKFWSDAVQAVPDTLYIHDLHARRVIFSNHHLGQQLGYNQEELARMGENFWETLLHPDDQEYYWRIRNLQHVVGDGLLLDSQLRWRHRDGRWHWFDIREQAFSRDRSGRVARLIGVAKDITFTVEANNALRENGRRYRMLAENISDVIFSTDAELNASYVSPSVQHVFGYSPEWALLNGLHQTATNPRQLGRLNGLLRRVRHAIGDRQKLAELRENPGQHLFALDCLRADGRKIPIELRIVLMWDEHDRFEGLLGIARDISQQRRAERELRMAATVFEHSTAAIMVTDPAGYIVQVNDSFSRLTGYSPADVLDQQPRLLTADRQEANQLKHVLASLQHSGSWEGEILQKRKTGELYPSWVGITAVRDEEGDLVSFVCFFSDISERKASERRIHRLAYYDALTHLPNRTLFQDRLHTALQQAERNGQWVVLMFLDLDRFKPINDSLGHAAGDRMLQEVATRLSACVSQDDTVARMGGDEFTLLLPSQGDREIALKRAIQVAELILGRLARPFTLEGREFFVTASIGVALSPQDGAELSLLMKNADTAMYHAKEMGKNNFQFYQAEMNARALERLELESDLRRALELGEFVLHYQPQFTGDGRRLTGAEALLRWQHPRRGLVPPSEFIPVLEEIGLVAQVGDWLLAEACKQLRSWHKAKVRVPKVSVNLSARQFADGQLGERIAAILYETGIPPACLELELTESILMSDVAEAMQILSGLKRLGLAIAVDDFGTGYSSLNYLKQFPIDVLKIDRSFVDGLPHGEQDAQIARAIIAMAHSLNLMVIAEGVESQAQLDFLREHGCDEVQGYLFGRPMPAEQFGMLYASDVLFMFNEG
Protein: GTPase activating protein, putative (Q38A97)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSDGGNVLGRPGDCNNCIETAKSNFHCSASTDASAAQNVPVPVPDPGLNATVGADSVLAPPVGTDEQDDDSSVESASVSASGNPENEENLLVDEFGFIIDEEEHDRVQRYIRGIDGKRVARREVKWQKMQANWESMSKKRRSKVKSRCRKGIPSSFRGAAWQLLIGSYLEMLNPGNEGTYDCLRLKDISDEGLKGTISRDLPRTFPKHVLFREEGGIGQTFLRNVLHAYANIDPEVGYVQGMAFVVGALYTQMTEEETFWALHTLMNGEKYRLREMYKPGFPMLHKLFYQLQRLMAKLLPNLYEHFEELGVHPTYYASRWFMTLFVYDFNFRAVLRIWDIFLSEGWKIIFRIAIVLLKLEERRLLAMSFEEIIFATKTLEQGKDPDELIRRAHGVRFKTAELEAFAREYELNKREGQV
Protein: TAP binding protein (A0A8I5ZLY7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MKVKGNRLGRGDRSTMKLLPLLVVVALGLATVVVSAGPQTIECWFVEDAGGGGLSKKPATLLLRHGPRGPPPRPDLDPKLYFKVDDPAGMLLAAFRRYPAGAHAPHCEMSSYIPFPASAKWARGLSPQQNCSRALDGDWLMVSVSGTVFSLSSLLRPLPEPQREPVFITMATVVLTVLTRHPAPRIHLGKDAVLDLRFAYAPPALEDAPSVASGPPPFGLEWRRQHRGKGHLLLAAIPGLLEKMPPAREKAVAFAAWDDDNDPWGPWTGNGTLWLPAVSPSQEGVYLATVHLPYLQGQVSLELTVHKPPRVSLTPAPIVWAAPGEAPPELLCLVSHFYPEEGLEVEWELRGGPEGSSRKAEGKTWVSTVRHHSDGSVSQSGHLQLPPVTDKQHGVRYACRVRHPSLPSSGRSAEVTLEVAGFSGPSIEDGIGLFLSAFLLLGLFKALGWMAAYLTIPKILKEKASATSLTVPKDEKKSE
Protein: Prostasin (EC 3.4.21.-) (Channel-activating protease 1) (CAP1) (Serine protease 8) [Cleaved into: Prostasin light chain; Prostasin heavy chain] (Q16651)
Organism: Homo sapiens (Human)
Function: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Subcellular location: [Prostasin]: Cell membrane; Single-pass membrane protein.; SUBCELLULAR LOCATION: [Prostasin light chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.; SUBCELLULAR LOCATION: [Prostasin heavy chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.
Interaction partners:
- Kunitz-type protease inhibitor 1
- Kunitz-type protease inhibitor 2
- Furin
- Epithelial sodium channel subunit alpha
Sequence:
MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH
Protein: Anti-silencing protein ASF 1 like protein, putative (Q4GZF6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Chromatin assembly factor 1 subunit B, putative
- Histone H4
- Importin N-terminal domain-containing protein
- Histone H4
- Protein kinase, putative
- Histone H3, putative
- Histone H3 variant
- Protein kinase, putative
- Protein kinase, putative
Sequence:
MSIQPIVQLLEIELIGDNPSSYTQPMHWRMRLEALEALDDTISIAFVWVGSAASPNHDQVLDSFDVGPLAQGVTEFTMECDPPQVELVPTQEVLGVTILVISFQYREQEFLRVGYYTQVAYFDGRMNNCPPPVPQVELMGRFIAMPRPTVTVTPIAWNGGPSEGREALEPR
Protein: Bactericidal protein attacin D (Q9GPI2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MECQASGNPKSGAATAQCGVRVGDDLANARAGVFASTPGAGGPVTKGVYGAVNANGHALSLQHGHIEGVGSTTTAAAQANLFQSNNAALNATAFHSHSRSHDQFGGGLNLQTGTGHQAAVGVTRVPQFGMTAVQASGTANLYTSPSGNLSLNATGSANHHLRGPMRGKSDFGTGVNLRYNF
Protein: Putative two-component response regulator ARR20 (Q9LZJ8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Two-component response regulator ARR17
- Histidine-containing phosphotransfer protein 4
- Histidine-containing phosphotransfer protein
- Histidine containing phosphotransfer protein
- Pseudo histidine-containing phosphotransfer protein 6
- Histidine-containing phosphotransfer protein 5
- Histidine-containing phosphotransfer protein 3
- Histidine-containing phosphotransfer protein 2
- Histidine-containing phosphotransfer protein 1
- Two-component response regulator ARR16
Sequence:
MSVFSNILDENSRNLRNEIPCDDGIASPINDDDEEFLTKSNRVLLVGADSNSSLKNLMTQYSYQVTKYESGEEAMAFLMKNKHEIDLVIWDFHMPDINGLDALNIIGKQMDLPVVIMSHEYKKETVMESIKYGACDFLVKPVSKEVIAVLWRHVYRKRMSKSGLDKPGESGTVESDPDEYDDLEQDNLYESNEEGSKNTCDHKEEKSPTKKPRMQWTPELHHKFEVAVEKMGSLEKAFPKTILKYMQEELNVQGLTRNNVASHLQKYRQSSKKTCTPQEPQEDFVWGNAGPDVTLAASKTLLSSHATPSYLINNQAAPRGSYFMNNIPYPSTSCLPVNNNNCFMTNPSTYIDQFQHQLQQQQQHQQYQSTLNSISAMLTKQESRHVPSSAMENSEPLMIYNSNLPFGIDECFPPAGFNIFDQIGHN
Protein: Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz) (P27358)
Organism: Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)
Function: Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit. The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin have permeabilized the inner membrane and degraded the host peptidoglycans. Host outer membrane disruption is due to local fusion between the inner and outer membrane performed by the spanin complex (By similarity).
Subcellular location: Host cell inner membrane {ECO:0000255|HAMAP-Rule:MF_04137}; Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_04137}; Periplasmic side {ECO:0000255|HAMAP-Rule:MF_04137}.
Interaction partners:
Sequence:
MNRVTAIISALVICIIVCLSWAVNHYRDNAITYKAQRDKNARELTLANRVITDIQMRQRDVAALDAKYTKELADAKAENDALRDDVAAGRRRLHIKAVCQSVREATTASGVDNAASPRLADTAERDYFTLRERLITMQKQLEGTQKYINEQCR
Protein: biotin carboxylase (EC 6.3.4.14) (Q729X1)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha
- Biotin attachment protein
- Bifunctional ligase/repressor BirA
- Glutamyl-tRNA
- DNA-directed RNA polymerase subunit omega
- Malonyl CoA-acyl carrier protein transacylase
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta
- 3-oxoacyl-[acyl-carrier-protein] synthase 2
- Biotin--acetyl-CoA-carboxylase ligase
Sequence:
MQTNDHKVLVANRGEIATRIVRACHRLGLEFTCVYTAEDAASGHVRLARELGGANSLYRVSSYHDANELLAVADDAGCTAVHPGYGFFAEDYRFARRVAQRERKLIFIGPSWRVIRELGDKINTKRLARSLGVPTVPGSDKPIYDELEAEKVAQSLYEFQEQQGIRRPLVLVKASAGGGGMGIEEVYDLDLFKSVYRRIRNYALRQFKDEGVLIEQRIRDFNHLEVQIVSDRTGRNPVHFGTRNCSIQSIGLQKRIEVAPGFDPTSIEYGFDAAQVLRDITYHSLAMARKVGYDNVGTWEWIVTRDGHPFLMEVNTRIQVENGVSARIARVNGQEVDLIAEQIRIGLGQPLGYGQEDITFEGVGIEYRLIAEDPDNRFTPWVGRIDAFGWPEEDWARMYTHVPTEEPYDIPTEFDPNLALAIIWGKDLEEVKRRGVSFLEGLTLQGQNKAGDELRSNVNFLRDNTGRILRF
Protein: Derlin (Q5ANB9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Ubiquitin fusion degradation protein 1
- RING-type E3 ubiquitin transferase
- UBX domain-containing protein
- UBX domain-containing protein
- Nuclear protein localization protein 4
Sequence:
MAQLTPIRGFTNTPVTRSICMISTVVPIMLSVLAIKYVVKFAIDPYIIQYNQFWRVVTYQLSVVNESDYLITVLLWFQFKVLERFYGSRKYLSIITLFTVYNAVACLFIMSLGQLLLYYILFVIKVFIMGYDQGSIHYNVTFLNEIIPGPLGILSSLYVCYGANIPVSYYFKILLKDPRNADQPETSSPSKELNLTNLFPIHILYTILILNNGLRSIIPCLVGLLIGKLYVYELLPGGSSWLLSNTVFRLFINPVKRAGVWLEAVRRRLSIRYERLSSGDSQEALEEEELNENNDEPDDNDEILDETRQQENQIRAETPVRPLGSQFLDTFRT
Protein: Cilia- and flagella-associated protein 44 (Component of motile flagella 7) (Q57WH1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Flagellar protein involved in flagellum axoneme organization and function.
Subcellular location: Cell projection, cilium, flagellum {ECO:0000269|PubMed:29449551}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:29449551}. Note=Closely associated to the axoneme along the paraflagellar rod. {ECO:0000269|PubMed:29449551}.
Interaction partners:
- Cilia- and flagella-associated protein 43
Sequence:
MAAPAQAVVKEKPPIHVYPQAKIGTKIFTHHGIHSMRYNGVCALTGSTVLMASGRFVMFVDVHKGTIESMQGPENGGVGAVAVHPSRQYYVVCERKPSDPAIRAYSWPSRTEVGEFVKGATKGFSACAFNKDGSMMATVGMYPDFFLTVWDWESRGMVLRSKCHNTDVYTVLFSPFDSGLLVSGGAGHIKFWTMANTFTGLKLQGLLGKFGRLEISNVSGFVVLSDGKVISGSESGLIILWEGDLIRCCFAREVDREDDDGTAATFMARSYDYTPCHEGAINVVELMEGGRVLMTAGDDGYFRFWRVSELEVAEGEGAPPLYVPECLGEILVHAGAFIRSVTYCKDVDEWVVLDSAGVLWRVPYVHPDDILNNAVTKPKEQAVPALEFNGGSITSAALSPIDHTVVTGGEDGTIRLVDYVTPRELYKMCLPQPNVVIGLRFFQKDPEKKKFLACCKSGAVLLVKRGSTAFTLLGQWRPHNDGLALFAVDAAEHRLCTIAHGTVFFFTILDDFSSLEPIGFCKIPLPGATCVAWDDASSCCLIGFECGKLLAIRAPTRDMVDQSVSYEFTCNYALVGIRQRKKVEKKQANVSAGEREGFVEEEEEEEYLGPWPVRLICPMADGDFAIGAGGVELLYKYGLHVRYEGQKELPPLPPTGIEPPDYVEEPLMNLCYRDYTPEASSMSYSGRYLVVICEGSQMLLRQLDEMGRVRLEPILVASAHDRLDGPIAAACTSFDDKMLVSVGSDGLVVAQLLDGCIAPQPPSPVAQLQPLRAEEIVEPQLAPFSITEQKDLDDRRRAEDEKRRELNLFLDKLKDVHQKYARLLRENQSLALTHRLSKEEITIHPQIYRELQEEMRQRVEESRKPTALELARENIRTRKMRNRFVDNLAHDRFLVRSFSKEFSVASFRTPYVDGSIKLFQQQIDELLGSERCSSLACDGDRGIVSVASGEASQQSPRNLSLSTAAGVVRWLNSEERKRNEGEQQKMNAAHREAEILTTTMRQYLNKMDERREERHWRKKGYEMLLAHKPDPAVEEASLNEELRRETRRRGECILRTDPSYHSAPSAVIKLQQLIRLEEIIFNMRNNFSNELLKLRDEKERLCGTLNVSLQRIRAINEKLKDKSFHADDVKLTPEEMPGKRFEISRDGLVAFMKQRQEEKLREQTAKKAQRGFGADLATGEPATNTDTSGADTPATRRSEGEDSRKVTISANRDSFGTAAARTRSVRTGTLAASKGGRPFSGGGFAAGAARERMNHELRVKHENIKLTEMEEEELQIERNRLLAERQRLHTQVQAMMDEFDVRLWSMYEERSRVDANLCLAHTHSLLLFREYNILLVFRQKDFELQSSYDEARNSRDRCLREMEELQRLVQDQTASIEKLQEANKVFRREVEIFISNSFPAEHVPYITKVFLRQIKRRKHHSDMSGNDDDITSDDDDDDDMGEDEAWEEICPPNCSEERWCEVIEKREVRLDYVDAITEERRQLEATEQRIEEHKALADKNNAAVSTCLKAIEDFQGEKRKQLNMLETLVAMRCGQVRCLDEEGRCPDTFRRNDLVVVSDKVITGLHDRIRALAEEKHDRRGKLKSMVAEQQALQRERSEKQALHTQWEEKIYEAMLLKFGQIVNLEVLESSCGSREVEQLKERLRLEELSWEKELRKRDKKIAVLREKLHESLEYNTSLLQTIGDQESDRQSVERSLAQSTQKVVSKMYDSINVATEEDRSNLRLLIAAQQEEIDALRTEVALLRTKGGHVYAAAMAAGR
Protein: Large tumor suppressor kinase 1 (Lats1 protein) (A9JTE1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MRRAEKPEGYRQMRPKTFPASNNSGNSQQMLQEIRESLRNLSPSSNASKPEQSSGKGPPDESRQQGRSTNPRNSHHHRALQEIRKSLQPFAHDSSSSGDNSSADSSKHTLQTQEPGFDEELMVNRINFQEAVREQIPSARPVNTAIKQAGPPQIQQPLLRRQSWKGSKESLAPQRHSALINDVLIYRPSSPGPQSDLSRPATFPQNLASASSGQRVNAPLSRQVRSITPPPSSWDSNPSTKRYSGNLDYLVPRISPVPQGPRGDGYINPQSQNQRGLSPVPVGRQPIIMQNSNSNKFNFPPSWPQNGSMQNEYMGMNSGARQPPPPPYSMHQTNRQSPTAQQMQSSALTAPPNGASLPQSMLVPNRNSHNLDMYNLGVIRPPVQQAQTPPGQDTSSSWTHSVPGRSNSFTSAPNNRRQCPNSQLSATTVTTVTQAPILQPVKSMRVQKPELHTAVAPAHPPWLQPPPPTAYQEPPTPPAPAAEVPSYQGPPPPYPKHLLQQQQPPPGYDSSPALKPCSKEGDAADNENDTDSTCSSERAEGSEEEKKQITTSPVPVRRHKRDEERKGESRLPMYSPQAFKFFMEQHVENILKNHQQRMRRKKQLESEMQRCVDLLLLPLPFFSLSDQLVFIV
Protein: CID domain-containing protein 1 (P34281)
Organism: Caenorhabditis elegans
Interaction partners:
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- 5'-3' exoribonuclease 2 homolog
- CID domain-containing protein
- RNA polymerase II subunit A C-terminal domain phosphatase ssup-72
- TM2 domain-containing protein C02F5.13
- Suppressor of forked domain-containing protein
- Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2
- Polyadenylation and cleavage factor homolog 11
- DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
Sequence:
MADFTEQTLRQKLTNLSNHPSSIQTTSAWLLQNHSNRELIIRVWLKTVKKETHGSKIVNLLYVANDVSQNARKTCPQFKDEFFPAIESSFRHAIELKNAKEVEHAIGKLINVWKDRQIFTPSQCKRLHEVHQQVKLSGSFPTPAVANKEHGKVAQPSQFVVEEAKKNAQDVLLSLKRLQNPPSTEREIRTELSKYPDNISCPEKLQSVRSSQEAQSLLVQNEEALPMLEEYVKRLKNETNERETLESNLNMLIENVRMSIEHHEKLCREVKRREDRIKADLLEVEKTFESLPDLAAEMPNAPLPTLEALFEKRKK
Protein: Enolase 1 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase 1) (2-phosphoglycerate dehydratase 1) (Q74K78)
Organism: Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Function: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00318}. Secreted {ECO:0000255|HAMAP-Rule:MF_00318}. Cell surface {ECO:0000255|HAMAP-Rule:MF_00318}. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. {ECO:0000255|HAMAP-Rule:MF_00318}.
Interaction partners:
Sequence:
MSVITDIHAREVLDSRGNPTVEAEVYTELGGFGRAIVPSGASTGEHEAVELRDGDKSRFLGQGVLTAVENVNGEIAKAVIGLDVTDQRLIDQTMIDLDGTPNKGRLGANAMLAVSLASARAAADELGLPLYEYLGGPNAHVLPTPMMNVINGGKHADNNVDIQEFMIMPVGAKSLHEAVRMGAETFHTLKSLLQERGESTAVGDEGGFAPNLKNNEEPFEILVEAIQRAGYKPGQDISIAFDCAASEFYNKDTKKYVTVADGREYTAEEWTSLMEDIVDKYPVISIEDPLDENDWEGWKVFTERLGDKVQIVGDDLFVTNTNYLEKGIKMGVANSILIKLNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEEALGSTAQYKGIHSFYNLHKQF
Protein: Transcriptional regulatory protein PHO23 (P50947)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Histone deacetylase RPD3
- Transcriptional regulatory protein SAP30
- Histone deacetylase complex subunit CTI6
- Transcriptional regulatory protein SDS3
- Transcriptional regulatory protein UME1
- Transcriptional regulatory protein RXT2
- Transcriptional regulatory protein SIN3
- Transcriptional regulatory protein DEP1
- Chromatin modification-related protein EAF3
- Transcriptional regulatory protein RCO1
Sequence:
MSSPANLFPGLNDITDVLEEFPLATSRYLTLLHEIDAKCVHSMPNLNERIDKFLKKDFNKDHQTQVRLLNNINKIYEELMPSLEEKMHVSSIMLDNLDRLTSRLELAYEVAIKNTEIPRGLRLGVDNHPAMHLHHELMEKIESKSNSKSSQALKSESRREAMAANRRQGEHYSASTHQQDDSKNDANYGGSRHESQDHTGNNTNSRKRANAANTNNADPETKKRKRRVATTAVSPSTISTATAVNNGRIGTSTASRGVSSVGNSNNSRISRPKTNDYGEPLYCYCNQVAYGEMVGCDGADCELEWFHLPCIGLETLPKGKWYCDDCKKKL
Protein: Sulfotransferase 3, isoform A (EC 2.8.2.-) (Q9W1L7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNRVQVTPRSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCGTTWMQELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSRYYHGVSFGFNYGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHENAGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDHSEVNNSERGEQIKQGQAV
Protein: Protein MON2 homolog (Q9VLT1)
Organism: Drosophila melanogaster (Fruit fly)
Function: May be required for traffic between late Golgi and early endosomes.
Interaction partners:
- Protein DOP1 homolog
- Vacuolar protein sorting-associated protein 26
- ADP-ribosylation factor-like protein 1
- Protein spire
- Guanine nucleotide exchange factor subunit Rich
- ADP-ribosylation factor-related protein 1
- LD29171p
- Protein cappuccino
Sequence:
MSFVGGGGCGGQDVHKFVEALQADFKTLSLETKKKYPQIKEACEEAISKLCTAGSSQQNSVYYTVNQILYPLVQGCETKDLKIIKFCLGMMQRLITQQVVDQKGALYITNALWTLMENNIEEVKVLQTVTLLLTTNTVVHGDTLAKALVLCFRLHYAKNPTIVNTAGATIRQLVSLVFERVYLEKDSVSSLQQQQSSGSPAEGEGGNQDVQTFASDAFLLFQDLVQLVNADQPYWLLGMTEMTRTFGLELLEAVLTNFSAVFHESNDFRLLLKERVCALVIKLFSPNVKHRQLPAPSNGNAPVPAEKPYFPISMRLLRLVAILIQKYHTILVTECEIFLSLIIKFLDPDKPAWQRALALEVIHKLVTRSSLIAFFCKSYDLKNHATNIVHDMIAAMGSYIRYSLINASAMLNGQQNGVANSLTAMSGSNQCGFMFRGAYLPLVATYAPGVSKAVYLEMLDKIDASNIPDSYGISVGHAILLDMTRSIGGVIQRTPELHPSHNTAVITEEEHKPLCLQLVNSSWSALLSAFIPLVETSIDEATTENILKAMQNYAALCGMLEQLQPRDAFIMAMCRASFPPHYAMSIFANTTQSDGDLRCHTRSGSQDLSSQFINSCSGDAGDFRPQIVAVGTPLPSASLPHSVMQAPVMLTNKNLQCMRAILFLAHNNGGILGTSWHIVLQTLQHLVWILGLKPSTGGSLQAMPKPAVEANVGIQTAVMADLPVLSQMLSQLFESSQYLDDVALHHLIDALCKLSHEAMELAYANREPSLFAVAKLLETGLVNMPRIKVLWRPLTNHLLEVCQHRHIRMREWGVEAITYLVKSALQFKHKTPLKENMELQTMLLSPLSELSTVLHADVRQRQLDCVLQILNTAGEILSFGWPAIIEIIGAVNEHHGEPLIRTAFQCLQLVITDFLTVMPWRCLPLCISTAAKFGSQTQELNISLTAIGLMWNISDFFNQNQDKLMSTQLQDVSILPDFPGTVKMPQFDKLWMCLYAKLGELCVDLRPAVRKSAGQTLFSTISAHGSLLNPPTWQALVWQVLFPLLDNVRALSSSASNEKVDASGNILIHHSRNTAQKQWAETQVLTLSGVCRVFNTKRELLQMLGDFERAWSLILEFIQNAALSKNGEVSLAALKSLQEIMYHNTAERTERALKDPQTAQEQDEEIWTIAWNIWLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFYIPSQAFLTALIQIFPAIFQHIQVKFTAADFDKFCTVLTNAVCIPVQTDAVPYIMSTVSDTLLTPLHDGILDCMELIQKEATKPDSHISQLIPAIFRQLLIFSKFACAPPTFQQSVEHKYAKSSGHYANNASVEVVSMNYIPFGEKSISICVKLYQTTATEDSVVQEQILHDIVKALRTPLAMKYKCLSSSTWKLAISSLISVLHTGLKVARAKPQHFASLWDDLADTLDKFLFPASVCTIEDRGLEEIVLDETIDCQVIELLRDEVLPHSHEMPHQFIMQIVVLLNKGSIHSASDTNICYESDWKLREIFAKTCFETLLQFSLLEDHANTNNNRLNANVLTAGAAGAGGKDFAGRLAVTALLHRFQEVLKRFNDDERQSGKCPLPRFRLSEISFVLKAIATLVVSMKKAPASKVNKPAWDQLIGLYPYLVDCTTTTSPEVSRSLREALLQYTDLLQAPRSCSAATSNDNVIQSNGQE