wanglab/gogpt-training-data huggingface dataset:
Protein: Paired box 6 (Paired box gene 6 (Aniridia, keratitis), isoform CRA_b) (A0A1W2PRA8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ
Protein: Plastin 3 (U3KQI3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYLWPKPFVLNSMFNKEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQ
Protein: Reticulon-like protein (F4I596)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363132}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363132}.
Interaction partners:
Sequence:
MAEEHKHEESIMEKISEKIHGHDDSSSSSSDSDDDKNSASLKTKIYRLFGREQPLHKLFGGGKHSENQDINERFGLVFAAADIFLWRNKKVSGGVLGAATVSWILFELLEYNLLTLFGHISILALAVLFLWSSASTFIHKSPLHIPEVHIPEDVVLQLASGLRIEINRGFTVLRDIASGRDLKKFLLVIAGLWVLSKVGSSCNFLTLIYIATVLLFTIPVLYEKYEDKVDDFGEKAMREIKKQYVEFDVKVLSKVMSKIPKGAFAFIKKKD
Protein: Trehalase (EC 3.2.1.28) (Alpha-trehalose glucohydrolase) (A0A0W0DQ98)
Organism: Candida glabrata (Yeast) (Torulopsis glabrata)
Interaction partners:
Sequence:
MSDPMDEGPLGKGAVATPAMVEKVANESPKKTRPRRLSSLNEFYDPFSTAEVYYGPATDPRKQKKSSTKLNRTRTMSVFDNTSIAKTTASFGQFQLKRRGSEDDSLTASQGNRKFFIEDVDGTLEELLSSEDTDRNYQITIEDTGPKVLKVGTANSGGYKHVNIRGTYMLSNLLQELTIAKSFGRHSIFLDEARINENPVNRLSRLITNQFWNNLTRRIDLNNIGEIASDTKVDTPEAKNPRVYVPYNCPEQYEFYIQASQMNPSMKLEVEYLPKDITPEYVKSLNATPGLLALAMEEHVNPATGEVSLIGYPYAVPGGRFNELYGWDSYMMALGLLESNKVDVARGMVEHFIFEIEHYGKILNANRSYYLCRSQPPFLTDMALVVFNRIGGDNNPNAIDFLKRSFKAAIKEYKTVWMAHPRLDPETGLSCYHPDGLGIPPETEPTHFDSILTPYAAKYYCTIPEFIAMYNDGSVKEPHLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEVDIANFIEKYHNDEYHDPFDGTVTNSAYWRDLAAKRKENITKYMWDEETGFFYDYNIKVKCRTNYESATTFWSLWAGLATPEQAKKMVELALPKLEMLGGLVACTEESRGPISIDRPHRQWDYPFGWAPHQILAWEGLNDYGYTSVATRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGADFKGVAKEGFGWVNTSYILGLKFMNSHARRALGACIPPAPFFNSLKDDEKSIYGL
Protein: Cytochrome c oxidase subunit 5b-2, mitochondrial (AtCOX5b-2) (Q9SSB8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular location: Mitochondrion inner membrane {ECO:0000255|PROSITE-ProRule:PRU00692, ECO:0000305|PubMed:25732537}.
Interaction partners:
- Cytochrome c oxidase subunit 6a, mitochondrial
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 6b-1
- Cytochrome c oxidase subunit 6b-3
- Cytochrome c oxidase subunit 6b-2
- Cytochrome b-c1 complex subunit 9, mitochondrial
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 3
- Putative cytochrome c oxidase subunit 6b-like
- NADH dehydrogenase 1 beta subcomplex subunit 7
Sequence:
MWRRIVSSHLKSISAVGSCAAPSCRHAVVESTHLSLSTRASSIPAYSSIFSRLIGSAAADTAVKKRVEDVMPIATGHEKEELQAELEGRKLDDIDFPEGPFGTKEAPAVVKSYYDMRIVGCPGGEGEDEHDVVWFWLEKGKSFECPVCTQYFKLEVVGPGGPPDGHGDDHH
Protein: NAD(P)-binding Rossmann-fold superfamily protein (F4JNJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At3g49420
- Alpha/beta-Hydrolases superfamily protein
- Alpha/beta-Hydrolases superfamily protein
- Polyprenal reductase 1
- Small ribosomal subunit protein eS17w
- Ribosomal protein S24/S35
- Expressed protein
- At4g13500
- Polyprenal reductase 2
- Small ribosomal subunit protein eS17z
Sequence:
MQSSNQISTEILRPLKKKIPNKSQRASGFSSRSTAEEVTHGVDGTGLTAIVTGASSGIGVETARVLALRGVHVVMAVRNTGAGAKVKEDIVKQVPGAKVDVMELELSSMESVRKFASEYKSAGLPLNLLINNAGIMACPFMLSKDNIELQFATNHLGHFLLTKLLLDTMKNTSRESKREGRIVNVSSEAHRYSYPEGVRFDKINDESSYSSIRAYGQSKLCNVLHANELAKQLKEDGVNITANSLHPGAIMTNLWGYFNSYLAGAVGAVAKYMVKSVPQGAATTCYVALNPQVAGVTGEYFSDSNIAKPIELVKDTELAKKLWDFSTKLTDSQ
Protein: Two pore segment channel 2 (D3ZTJ6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Two pore calcium channel protein 1
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- Unc-79 homolog, NALCN channel complex subunit
Sequence:
MAAEAQPLLGRDRGGGQAHSGADQELCIDQAVVFIEDAIKYRSIYHRLDAGSLWLYRWYYSNVCQRVLGFTIFLILALAFVEVPSSFTRTADVRYRSQPWQPPCGLTETIEALCLLVFLADLSVKGYLVGQAQLQQNLWLLAYFVVLVVSVVDWIVSLSLNCEESLRVRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLTIHLCLFTVIGMLLFTIAEKDEAQNKERLTYFRNLPEALTSLLVLLTTSNNPDGSLFLMNLLTAIIYNQFRGYLMKSLQTSLFRRRLGARAAYEVLTLQAGPNGTTSELVGVNPENFLRVLQKTQLNKIHKQAIIQKVHSYEGRPILADEFQKLFDEVDKGIVKERPPKPQYQSPFLQTAQFIFSHRYFDYLGNLIALGNLLSICVFLVLDSNLLPGERNDFVLGILNYIFILYYLLELLFKVFALGLRGYLFYHSNVFDGLLTIILLVLEISTLAVYRLPHPGWKPEQYGPLSLWDMTRLVNILIVIRFLRIIPSIKPTAVVASTILGLIQNLRAFGGILVVVYYVFAMIGINLFRGVIVPPGNSSLVPDNSSAPCGSFEQLGYWPNNFDDFAAALITLWDVMVVNNWQVILEAYKHYSGPWSMVYFVLWWLVSSVIWINLFLALLLENFLHRWDPQGHKQLLVGTKQITYEMSVELMFRDILEEPKEEELMEKLHKHPHLHLCR
Protein: Pleckstrin (Q9JHK5)
Organism: Mus musculus (Mouse)
Function: Major protein kinase C substrate of platelets.
Interaction partners:
- Mcf.2-transforming sequence.
- Tyrosine-protein kinase BTK
- RAC-alpha serine/threonine-protein kinase
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
- Oxysterol-binding protein 1
- Proto-oncogene tyrosine-protein kinase Src
- Guanine nucleotide exchange factor MSS4
- Cell division control protein 42 homolog
Sequence:
MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCLTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPAGDLSKNAADGIAENPFLDSPDAFYYFPDSGFFCEENSSDDDVILREEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAVHLRGCVVTSVESSHDVKKSDEENLFEIITADEVHYYLQAATSKERTEWIKAIQVASRTGK
Protein: Guanylyl cyclase 1 (AtGC1) (EC 4.6.1.2) (Q8L870)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Magnesium-dependent guanylyl cyclase that catalyzes the formation of guanosine 3',5'-cyclic monophosphate (cGMP) from guanosine 5'-triphosphate (GTP). Can also use ATP as substrate with a low activity.
Interaction partners:
- Wall-associated receptor kinase-like 10
- Phytosulfokine receptor 1
- Cyclase-like protein 1
- Wall-associated receptor kinase-like 17
- Potassium transporter 7
Sequence:
MWPLCFLLNKLLRVEERNQGILDGNGDSTFPKYCLFDDPLVSDGKYRDAGLPSSSHMDVPHVHQLASWDCGLACVLMVLRASGIASCTLEDLAEICSTNSIWTVDLAYLLQKFCVEFSYYTITFGANPNYSIEEFYKEQLPEDLVRVDLLFRKAHESGIIIQCRSVSIHEISCLLLSGNYIAIALVDQDKLSKSWLEEVLVSGLHSSNSCYTGHYVVICGYDAVRDEFEIRDPASSKIHERISSKCLENARKSFGTDEDLLLINLENMRNQNGY
Protein: Activating transcription factor-2 (Q2PE13)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription factor Jra
- Mitogen-activated protein kinase p38a
- Mitogen-activated protein kinase p38b
- Putative mitogen-activated protein kinase 14C
- Stress-activated protein kinase JNK
- Extracellular signal-regulated kinase 7
- Histone H2B
- Mitogen-activated protein kinase kinase kinase 4
- Transcription factor kayak, isoforms A/B/F
Sequence:
MDTAGDMDHLASVSFGDFETKSPEGDVSCYQNFRAQTEHVSLDISLGQKSDTLFAADQTPTPTRLIKNCDEVGLFEDLQHVNPFDIGFQQAAERNVSGTPSRPEARPNDGESLHTPQVYPVEAPTVVSVPSENQVPQSVSCGDMDVDQLLATTVTSPSKASQDGPPPLQLIQPQVLTWVLPAQSVPISIATVDCNRNRVKPTGAIHPFILPKPTAKELNKTSKRPEPILVSCNPPNNEPSSASLTPTSQLPIKERLKAIIHSNNNRRSFSTPPKAAKAKDRSRDEDCMERRRAAASRYRNKMRNEHKDLIKQNAQLQQENQELHERISRLEKELQQHRSHSSLAGVVADQLRIPPSSIHLLINVPNVLVPSSASNASAAKK
Protein: Selenocysteine-specific elongation factor (SelB translation factor) (P14081)
Organism: Escherichia coli (strain K12)
Function: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
Subcellular location: Cytoplasm.
Interaction partners:
- L-seryl-tRNA
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS17
- Selenide, water dikinase
- Small ribosomal subunit protein uS12
Sequence:
MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAYWPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLTGNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGMDALREHLLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRVRALHAQNQPTETANAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHTPLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRLVLRDISARNTLAGARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGEGMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMALPMEDEALVLLLIEKMRESGDIHSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWWVRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGSTCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPEK
Protein: Nebulin (A0A1B0GSF5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MADEEEYEEVIEYYTEETVYEEVPGETITEVYETTTTRTSDYGQSETATPALAQPQPAKPVERKKVIRKKVDSSKFMTPYIQHSQKMQDLFSSNKYKENYEKAKGQPYAITSDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKALFYPYNDSPELRRVAQAQKALSDIAYKKGLTEQQTQFTSLPDPPEVEFAKKVTNQVSKQKYKEDYEKKVKGKWSETPCFEIATARMNADNLSSRKYQEDFENMKDQIYFMQTETPEYKMNKQAGVAASKVKYKQDYEKNKGKADYNVLPASENPLLRQLKTAGNVLSDKLYKENYEKTKARSINYCETPKFQLDTVLQNFSSDTKYKDSYLKNILGHYVGSFEDPYHTHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHAYKVHPDKTKFTQVTDSPVLVQAQVNSKQLSDLNYKAKHESEK
Protein: Anion exchange protein (M9PCT2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Membrane {ECO:0000256|RuleBase:RU362035}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362035}.
Interaction partners:
Sequence:
MPQQAQLKHIHGHGRLPRVIATESSRPWTMNSSSGDDEAPKDPRTGGEDFTQQFTENDFEVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGMLVKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIRSLADMRNHSSSKKDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEEARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSNASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEVGLLARIFPWGKGSRSRVVTKPPGLDDGIVGSGGAVGAGLITCTTSNANEKEFEAQSSLLKK
Protein: Thymopoietin (Thymopoietin a isoform 2) (Tmpo protein) (Q7ZTV0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSEFLEDPSVLTKDKLKSALLANNVALPNGDQRKDVYVQLYLKNLTVQNKKSSGSPDVFSSDEELPPAPVVSNRSRSGRKATRKTDKVRPDDVDVTELSNEGLKDLLLKYGLNAGPIVASTRKVYEKRLQKLLDQGPPVAVALPSETSQTDGNQNGNNDSDQYSDREEEPVAPAPVTVPEPEVEAELIPVVERPVRSRGKTPVTSRTRSGQHTREDVEEEDWPVLNVKRKLKRSSHRPDQMVPASDDTENSELSSAECFAVSEDRRRTGPGAGRRETRPLLSDRTSKLSSKSESLRRRSAPVRSVLNEASSSDKDFSEPSIVKEVSVSLMRMKVQPLTVPKDPKPSKRYSMSATESTKRPVSSLNNKHDENTADIPSPPHRQSSREPLVSLINTACVEVDDQGMQDVLSCRSANGGLLAQGVRSAAVSKLSKPVLSQSKPSKPLVDMMCCLSPSSDRQKEESCGSPQTHPKSRHSKITPFLSQITPVRGLDNKLMDMKETMMVEKVSAIDQTPRAVERDVLKEIFPTENLNTPTGISATCRRPIRGAAGRPLIDTWLNESRQRLSDLKQTTSSSSFSSTSSYTESRSVPRVSSIPLSASKSTAPPTVKSRSRRSLPVWVQLVLLSAVAGFLFFIYQAMETNDVGLFKQSGTDDSTSK
Protein: Cox15p (A0A1D8PPE8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Protoheme IX farnesyltransferase, mitochondrial
- SURF1-like protein
- Cox11p
- Holocytochrome c-type synthase
- Cu-binding protein
- Adrenodoxin
- Cytochrome b-c1 complex catalytic subunit, mitochondrial
- coproporphyrinogen oxidase
- Cytochrome c oxidase subunit 1
- Ferrochelatase
Sequence:
MLSKTRFFFTKNSLVLNTLQQNKGCKLSIVSRTAPASKLFPSSFKISRIFNNLSKRKYSTISHRVDSTFTKTEFVKSTPPPVIPQKSIGYWLLGTSTLVFGIVVLGGLTRLTESGLSITEWKPVTGAVPPLNQQEWEEEFNKYKNSPEFKQLNSHITLDEFKFIFGMEWGHRLVGRCIGAFFILPALYFWARGRFTPQLTKRVVGLTGLLGLQGFIGWWMVKSGLDEEQLAERKSKPTVSQYRLTTHLGAAFLMYLGVLWTAFEIFNENKLANLAKKSPEAVQAILKQLNNPALKKTKIVGLSLLALTFVTAMSGGMVAGLDAGLIYNTFPHMGDDWIPNGSELMSPVFSRKSDQSDLWWRNLLENPTTVQLVHRIFATTTFFAVLGAHIYVNRNKGVVPIAAKRIMHGVMGVVTLQVALGITTLIYLVPIPLAALHQAGALALLTASLAFSAKLKKPRPQFVQFINSNMKSKLLKTRV
Protein: Iodotyrosine deiodinase 1 (EC 1.21.1.1) (Iodotyrosine dehalogenase 1) (F6VN83)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQVNNGITMRHQTARHRHLIEGPGRSSEACSKLSSQGCPGASAAGSLFHFAIEFAAP
Protein: Uncharacterized protein C2F7.09c (Q09700)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MSFTKFCRGCGQTLQSANESATGYIKPLKLSGIFSKGSVSNLLKKNLDEQAIFNNAFKNLNPQIKKHFPNTTSFPFHEKEIGRTDLLWCQRCHDLKFHSRIRPKELLQEPQTTLPDIISTVNNDKSTCLIIQVIDVTEVIFQDFVSATQYTHFPVFHLFTHADVLPPKKPYWLFPGLGISSKYAMLYTSHSFNLVDKLLGRINPLLCSRGHVYVVGEANSGKSTLLKTLAKRGNGVFNELLLDSFLPGTTQAIKGYPTQYFGSCFKQLSEGLIFDTPGYRGNLKSLLPWVDTKLLTSLVPKTRSRNKQLTSKPVQYRVRFGQSIILGGLVRVTPFEINEDGNHEVGKPIMFKKEDPSSTTIHFLFSTLKNKKTKGNTNNMKPLLIKLFTKLPAHITSITKLQSLENSTKNDNVPLVTHSPSPMHSSFTVSIKPTQLSENVFDPTSSGELVIHNFGFLSFSASRPMNLLVESVNPKAVSWRSAKPVVPKFNK
Protein: Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta) (GABAAR subunit delta) (P22933)
Organism: Mus musculus (Mouse)
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P18506}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O14764}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit alpha-4
- Trafficking protein, kinesin binding 2
- Huntingtin-associated protein 1
- Inactive phospholipase C-like protein 1
- Vesicle-fusing ATPase
- Gamma-aminobutyric acid receptor subunit beta-3
- Gamma-aminobutyric acid receptor subunit alpha-6
- Gamma-aminobutyric acid type B receptor subunit 2
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit beta-2
Sequence:
MDVLGWLLLPLLLLCTQPHHGARAMNDIGDYVGSNLEISWLPNLDGLMEGYARNFRPGIGGAPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPLDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKRKAKVKVTKPRAEMDVRNAIVLFSLSAAGVSQELAISRRQGRVPGNLMGSYRSVEVEAKKEGGSRPGGPGGIRSRLKPIDADTIDIYARAVFPAAFAAVNIIYWAAYTM
Protein: Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1) (P05155)
Organism: Homo sapiens (Human)
Function: Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
Subcellular location: Secreted.
Interaction partners:
- Complement C1s subcomponent
- Mannan-binding lectin serine protease 2
- Complement C1r subcomponent
- Kallikrein-4
- Plasma kallikrein
- MBL associated serine protease 1
- Coagulation factor XII
- Complement C1q subcomponent subunit B
- Mannose-binding protein C
- Complement C1q subcomponent subunit A
Sequence:
MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA
Protein: Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) (P46413)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes. Participates in ophthalmate biosynthesis in hepatocytes (By similarity).
Interaction partners:
- Glutamate--cysteine ligase catalytic subunit
- Glutamate--cysteine ligase regulatory subunit
- Glutathione hydrolase 6
- Glutathione reductase
- Glutathione hydrolase 7
- Glutathione hydrolase 5 proenzyme
- Glutathione peroxidase 2
- Glutathione peroxidase 1
- Phospholipid hydroperoxide glutathione peroxidase
- Glutathione peroxidase 3
Sequence:
MATSWGSILQDEKQLEELAQQAIDRALAEGVLLRSAKNPSSSDVVTYAPFTLFPSPVPSTLLEQAYAVQMDFNILVDAVSQNSAFLEQTLSSTIKKDEYTARLFDIYKQVLKEGIAQTVFLGLNRSDYMFQCSADGSKALKQIEINTISASFGGLASRTPAVHRHVLNVLNKTNEASKILSNNPSKGLALGIAKAWELYGSANAVVLLIAQEKERNIFDQRAIENELLDRKIHVIRRRFEDVSERGSLDQNRRLFMEDQEVAVVYFRDGYMPSQYNAQNWEARLLLERSCAAKCPDIATQLAGTKKVQQELSRVGLLEALLPGQPEAVARLRATFAGLYSLDMGEEGDQAVAEALAAPSHFVLKPQREGGGNNFYGEEMVHALEQLKDSEERASYILMEKIEPEPFRNCLLRPGSPAQVVQCISELGIFGVYVRQGTTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV
Protein: rRNA 2'-O-methyltransferase fibrillarin (Histone-glutamine methyltransferase) (Q8IM23)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Nucleolar protein 5, putative
- Nucleolar protein 56
- U3 small nucleolar RNA-interacting protein 2, putative
- Nrap protein domain-containing protein
- U3 small nucleolar RNA-associated protein 7, putative
- Periodic tryptophan protein 2, putative
- H/ACA ribonucleoprotein complex subunit 2
- U3 small nucleolar ribonucleoprotein protein IMP4, putative
- U3 small nucleolar RNA-associated protein 13, putative
- U3 small nucleolar RNA-associated protein 4, putative
Sequence:
MTDSFRGGSGNFKRNSNNFGKGNNNAVRKGSNWKGFNGGRGGGGGGRGGGGGGRGGGGGGRGGGGGRGGGGGRGNKDRKSFKKDNKSGKVIVVPHRFPGVYLLKGKSDILVTKNLVPGESVYGEKRYEVMTEDEKIEYRVWNPFRSKLGACLMGGVGNMPIKPGSKVLYLGAANGTSVSHVSDMVGDEGVVYAVEFSHRSGRDLTNMSKKRSNIVPIVEDARQPTKYRMLVDMVDVVFADVAQPDQARIVAMNAHMFLKTGGWFIISIKANCVDSTAKPEVVFASEMEKLKKENCKPKEKLTLEPFHRHHAIVLGMYR
Protein: Flagellar protofilament ribbon protein (Q9M6B0)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000256|ARBA:ARBA00004611}.
Interaction partners:
Sequence:
MGRLVAQVPNEDPERLKRVLDAKWRTIGVDKETLELQAQEKKDREQAEKDRDEAFARLTAYFDDQLTLMQQEADQIRKAYNHDTEAFRQQQQLKHTRREWDINRPDAKQLDMPGRVGDDDNRLGPSSLQKFDGEDLTAGDRKKAQIEQSVNWWAEQTAIRDALRAAEKEAETAHAELVKYQDLLQQTAKSEEAAVRREVARATADYNKRLAEEKRLREYAAKQADLAANMAEMEATITSSFMTEDPNMAASSMSAYRVRKDHYKGMTETEKQAILDAQLAQMEEKKARRAQEQLENMMYARTQHDIQRALQEQAQRVDDFKKAQMARASEILKKQQEEKAERDKHLASLYRNKMAPEFFTQFGTSHR
Protein: Early transcribed membrane protein 13 (Q8IEU1)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKVSKLVLFAHIFFIINILCQYICLNASKVNKKGKIAEEKKRKNIKNIDKAIEEHNKRKKLIYYSLIASGAIASVAAILGLGYYGYKKSREDDLYYNKYLEYRNGEYNIKYQDGAIASTSEFYIEPEGINKINLNKPIIENKNNVDVSIKRYNNFVDIARLSIQKHFEHLSNDQKDSHVNNMEYMQKFVQGLQENRNISLSKYQENKAVMDLKYHLQKVYANYLSQEEN
Protein: trypsin (EC 3.4.21.4) (Q9D7Y7)
Organism: Mus musculus (Mouse)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKTLIFLAFLGAAVALPPDDDDDKNVGGYTCQRNALPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDALEGGEQFIDAAKIIRHPNYNANTYNNDIMLIKLKTAATLNSRVSTVALPRSCPSAGTRCLVSGWGNTLSSGTNYPSLLQCLDAPVLSDSSCTSSYPGKITSNMFCLGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGYGCAQRGKPGVYTKVCKYVNWIQQTIAAN
Protein: Acid-sensitive two pore domain K+ channel dTASK-6 (TWIK-related acid-sensitive K[+] channel 6, isoform C) (TWIK-related acid-sensitive K[+] channel 6, isoform F) (Q9VFS9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Uncharacterized protein, isoform C
- IP11374p
- Potassium channel domain-containing protein
- BcDNA.GH04802
Sequence:
MKKQNVRTISLIVCTFTYLLVGAAVFDALESETEKRRWEALQDAEDMIIRKYNISQEDFKVMETVVLKSESHKAGQQWKFTGAFYYATTVLTTIGYGHSTPSTVGGKLFTMCYAIVGIPLGLVMFQSIGERVNRLSSYVIKAVRSSLRCKRTVASEVDLICVVTTLSSLTIAGGAAAFSKFEGWSYFDSVYYCFITLTTIGFGDMVALQRDNALNRKPEYVMFALIFILFGLAIVAASLNLLVLRFVTMNTEDERRDEAQAMQALQVAVKLEGDVITSNGSILSGYEGHDGQSLNGSNTSSMCSCHCICLNGNRHKKSSNLEKNNDAENQYKLRQSPTHIRHLLPEVVPMQDLNYDYDTQSLHTLADRGTMDSSYMGVDMADMGDTGSMELRPHTLLKRNVSLLSIRI
Protein: FERM and PDZ domain containing 4 (A0A8I6ALF4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAATWSLLCLSHRTKSSGWPPPSGTWGLNQVPPYGWEMMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEPVSAAPRERVIDLVRSCKESILFTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRTEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGTENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKAVEMTDSTLCPKEHRHLYIDNTYSSDELSQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTLGYERMLDENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVSEINQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHENKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPTVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKTPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLAEGEGKCPLSGNVPGKKQQGTKIAETEEDTKGKVGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGVEAPAMKAFPRGPGLGNREAEGKEDGTMEGEADDASGLGQGERFLSDMACVASAKDLDNPEDTDSPTCDHATKLPEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHLIPDASGKGGSYISPEERVAGHPNHGATFKELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTV