wanglab/gogpt-training-data huggingface dataset:
Protein: H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10 homolog) (Q54J26)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Required for ribosome biogenesis. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000250}.
Interaction partners:
- H/ACA ribonucleoprotein complex subunit 2
- Probable H/ACA ribonucleoprotein complex subunit 1
- Probable H/ACA ribonucleoprotein complex subunit 4
- NHP2-like protein 1 homolog
- Nucleolar protein 56
- Nucleolar protein 58
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- CS domain-containing protein
- Eukaryotic translation initiation factor 2 subunit 1
- rRNA 2'-O-methyltransferase fibrillarin
Sequence:
MHLMYYNDKDGQRVYTLKKESPNHEATYSAHPARFSVDDKYSRERIALKKRFGLLLTQQPPLEF
Protein: T. brucei spp.-specific protein (Q584L5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAQVTQRQRGQWRARRGCDFVLEGVPMYDSPDLSSESSDSEEPQGVITRGFQSVNPTEHGYPARHVATYATMQPTTAVWHPNAGWQKALLQQRLYEGQLQQQELLRAEQPRHQQQVARNRYGAREPRRLPGLNPEGRESPVMPKQCQLVDDVDYVKYFSEEAKTGLFTMSSAFNVRSLGAVASHSQGARNLRSGQQQVQCLDNSSNGDKSTADYYILGESGGGSYVETQQTVNGGESRQLETRGIQTTSGCSPRNEGVHYLSNEFNSTGALNLYAIDLDNSGIYTPATCGSVDRAAASLERRCNSDMSQSNRTSVNTSSTGGWTTASTATISQYRNVVAGESGHTHFCNTDYNFAPSGMWRSNSSTFRGVCLHIEPTSPSAPPHTNANWRDDNEGCKMSVSPFLAESRNSLLGGQNFQHLLYKQEDPQVDERYDNAISDHPMPREYCYMESYLTDPKAPIQAKPDKVRPPVLSDEITGRGETRASGKLSTRLSPVRGFCYGV
Protein: Transcriptional regulator PsrA (Q9HZJ9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- RNA polymerase sigma factor RpoS
- histidine kinase
- Response regulator GacA
- LexA repressor
- 3-methylmercaptopropionyl-CoA dehydrogenase
Sequence:
MAQSETVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRQAKPEAQHATLEDLLHLLVSQAMAVKPRSGNDLSIFMRLLGLAFSQSQGHLRKYLEEVYGKVFRRYMLLVNEAAPKLPPIELFWRVHFMLGAAAFSMSGIKALRAMAETDFGVNTSTEQVMHLMVPFFAAGMRAESGIDDPLLAGAQLRPRNKTPAKA
Protein: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Q6DH83)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|PIRNR:PIRNR037825}. Cytoplasmic vesicle membrane {ECO:0000256|PIRNR:PIRNR037825}; Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR037825}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|PIRNR:PIRNR037825}.
Interaction partners:
Sequence:
MSSDEDRAKEILKGFKLNWMNLRDAETGKVLWQGTEDLSLPGVEHEARVPKKILKCKAVSRELNFSSVEKLEKFRLEQKVFFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPANVLTGNVVIETKFFDDDLHVSTSRVRLFYV
Protein: 2-oxoacid:ferredoxin oxidoreductase subunit beta (OFOR) (EC 1.2.7.11) (P72579)
Organism: Sulfolobus sp
Function: Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11683888, ECO:0000269|PubMed:8902625}.
Interaction partners:
Sequence:
MAAFTPQWNDWCPGCGNFGILNAEQQAIVELGVDTKNVVVVSGIGCSGKIPHFFRTPISGVHTLHGRAIAFATGIKLSNPDLVVIVNGGDGDLLGIGAGHFVAAGRRNVDMVVILHDNGVYGLTKGQASPTLKRGEKPKSLPRPNINDAVNPIALAISSGYTFVARGYAYDVKHLKELIKSAIKHKGLALIDVLQPCPTYNDINTKEWYDKRIYKLDTLPDWDPVVKKPEEVNEKIKRAIDKSLEWGDRIPIGIFYQNELVPSYEERIKANSPAYLDYTPAKQLIEKEGKLTTIIDPLLKEREVD
Protein: Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (A0A5F9ZI66)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
Sequence:
MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGASAMLIQKL
Protein: Protein TIFY 10a (OsTIFY10a) (Jasmonate ZIM domain-containing protein 6) (OsJAZ6) (OsJAZ5) (Q84R94)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Repressor of jasmonate responses.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
Interaction partners:
- Coronatine-insensitive protein homolog 1a
- Transcription factor MYC2
- Coronatine-insensitive protein homolog 1b
- Os10g0506950 protein
- Coronatine-insensitive protein homolog 2
- Protein TIFY 9
- Protein TIFY 5
Sequence:
MASAKSGERGSSSFAMACSLLSRYVRQNGAAAGELGLGIRGEADANKGKETMELFPQNSGFGSEAAAVKETPDAREQEKRQLTIFYGGKVLVFDDFPAEKAKDLMQMASKSSSTAQNCVLLPSSATATVADNTKVSAVPAPASALPVAQANAPKPVRPNAADLPQARKASLHRFLEKRKDRLQAKAPYQGSPSDASPVKKELQESQPWLGLGPQVAAPDLSLRQESSQ
Protein: Lipase (EC 3.1.1.3) (Diheptanoyl glycerophosphocholine esterase) (EC 3.1.1.-) (Extracellular lipase) (GDSL-like lipase) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (SRL) (Q93MW7)
Organism: Streptomyces rimosus
Function: Catalyzes the hydrolysis of p-nitrophenyl esters, alpha- and beta-naphthyl esters, and triacylglycerols, with a preference for medium acyl chain length (C8-C12). Shows a much higher hydrolysis rate of glycerol esters of unsaturated C16 and C18 fatty acids than that of their saturated counterparts, and a preference for cis double bond. Is also able to hydrolyze several natural oils and Tween detergents. Also displays thioesterase and phospholipase activities, towards palmitoyl-coenzyme A and diheptanoyl glycerophosphocholine, respectively. Shows transesterification activity of racemic 1-phenyl ethanol with vinyl acetate in hexane, proceeding with partial (R)-enantioselectivity.
Subcellular location: Secreted {ECO:0000269|Ref.3}.
Interaction partners:
Sequence:
MRLSRRAATASALLLTPALALFGASAAVSAPRIQATDYVALGDSYSSGVGAGSYDSSSGSCKRSTKSYPALWAASHTGTRFNFTACSGARTGDVLAKQLTPVNSGTDLVSITIGGNDAGFADTMTTCNLQGESACLARIAKARAYIQQTLPAQLDQVYDAIDSRAPAAQVVVLGYPRFYKLGGSCAVGLSEKSRAAINAAADDINAVTAKRAADHGFAFGDVNTTFAGHELCSGAPWLHSVTLPVENSYHPTANGQSKGYLPVLNSAT
Protein: Midkine and pleiotrophin 2, isoform E (M9PE21)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNLILALTTALHLVLVVLAHNPLSTRGESLSDGIRLVMEKRSGDVVHIRPARGTLEAETVASTTNSDTHRTRNNRKPNKPQEHSQQVGAHKSGSRKLVVAENGGALSSQLPQPNHKQGHKNTDKQQRGGGSKQQRGHSQHHGGNRKGPKAATPENGSTCRYAKSAWSNCDHKTNMRSRVLSLRKGEQNCLPTRTIQKKCKKGCRYEKGEWSQCVGGQITREDKLEPEATGGSDQNCNPVRTVSKKCKANGNSSGGKQHGQSRRTKEQKQKDKGKRASHISS
Protein: Small ribosomal subunit protein uS11 (30S ribosomal protein S11) (P9WH65)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
Interaction partners:
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein uL4
- Large ribosomal subunit protein bL17
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein bL21
- Large ribosomal subunit protein uL30
- Large ribosomal subunit protein bL9
- Large ribosomal subunit protein bL25
- Large ribosomal subunit protein bL33B
Sequence:
MPPAKKGPATSARKGQKTRRREKKNVPHGAAHIKSTFNNTIVTITDPQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQDHGVRKVDVFVKGPGSGRETAIRSLQAAGLEVGAISDVTPQPHNGVRPPKRRRV
Protein: NAC domain containing protein 61 (B3H506)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MGEELSVGFRFYPTEVELLTYYLRIQLGGGNATIHSLIPILDVFSVEPTQLPNLAGERCRGDAEQWIFFVPRQEREARGGRPSRTTGSGYWKATGSPGPVFSPDNRVIGVKKTMVFYTGKAPTGRKTKWKMNEYKAVETASVSTIPKLRPEFSICRIYIKSGSSRAFDRRPTEAYAIERNLPSNGVETSSRATISTSPETSHSGGNQVDLPVNATTITQSISDMVDELSQPFWEWEQMNWS
Protein: Type-1 angiotensin II receptor A (Angiotensin II type-1 receptor A) (AT1 receptor A) (P29754)
Organism: Mus musculus (Mouse)
Function: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P30556}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P30556}.
Interaction partners:
- Angiotensinogen
- Guanine nucleotide-binding protein G
- Angiotensin-converting enzyme 2
- Plasminogen activator inhibitor 1
- Guanine nucleotide-binding protein subunit alpha-12
- Type-2 angiotensin II receptor
- Beta-arrestin-1
- Prothrombin
- Guanine nucleotide-binding protein subunit alpha-11
- Type-1 angiotensin II receptor B
Sequence:
MALNSSTEDGIKRIQDDCPRAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSAAKKPASCSEVE
Protein: Serine and arginine rich splicing factor 5 (G3V5K8)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRR
Protein: Glycerol 2-dehydrogenase (NADP(+)) (Q5ADT4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Dihydroxyacetone kinase
- glycerol kinase
- NADP-dependent oxidoreductase domain-containing protein
- Glycerol-1-phosphatase
- Acylglycerol lipase
- Serine aminopeptidase S33 domain-containing protein
- NADP-dependent alcohol dehydrogenase
Sequence:
MPAQLQVNTDYFTLNNGNKIPAVGLGTWQATNEDEAYRAVLAALKNGYKHIDTAAIYGNEEQVGKAIKDSGVPREELFVTTKLWNADHKNIEEALETSLKKLGLNYVDLYLIHWPASIDKSTNKPYTDFDYVDTYRGLQKVYKNSKKIRAIGVSNFTKKKLERLLSSEGVDVVPAVNQIEAHPLLTQPELYDYLKEKGIVLEAYSPLGSTNSPLFKNETIVKIAEKNGVEPAQVLVSWAIQRKTVVLPKSVTESRVISNLKTFTLPSEDFETLNKLSEKDGVVRTCNPAFNNFDD
Protein: Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) (Q6NMI3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for normal Golgi function.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- Conserved oligomeric Golgi complex subunit 7
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 8
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 2
- Proline-rich family protein
- Vacuolar protein sorting-associated protein 54, chloroplastic
- Vacuolar protein sorting-associated protein 52 A
Sequence:
MASTVGLAPGLSRKLKKVLDCRTDSPDLVASLNALSSFYDENSAHARRNLRSTIEKRALQINSEFLNAADSTQIALDRVEEEVNALADCCDKIAAALSSSAATTSDIISTTERLKQELEVTTQRQEIVNCFLRDYQLSNEEIKALREDELNENFFQALSHVQEIHSNCKLLLRTHHQRAGLELMDMMAVYQEGAYERLCRWVQAECRKLGDTDNPEVSELLRTAVRCLKERPVLFKYCAEEVGNLRHNALFRRFISALTRGGPGGMPRPIEVHAHDPLRYVGDMLGWLHQALASERELVHALFDIDSADHQSNAKNTSENIALKAGESDFTFVLDRIFEGVCRPFKVRVEQVLQSQPSLIISYKLTNTLEFYSYTISDLLGRDTALCNTIGMVKDAAQKTFFDILKTRGEKLLRYPPPVAVDLSPPPAVREGVSLTLEIIENYNSMMVSASGEKPAFDPVLSALLDPIIKMCEQAAEAHKSKKSGQLPRRSRTSSDSSQLTSVDALLSSSPSPPQNNETPSKIFLINCLCAIQQPLLRHDVASQYVTNIGLMIENHINLLVQNEVDTLLHKCGLSDKMQIFRSSTSELPLSERQDTSPAMLSECLKAFFGLVLGSEGSLPEFEQIQVPKLRSEACVRVAKTLAEAYEVIYQAVTDQQNGYPDPKSLARHPPDQIRTILGI
Protein: Chemokine-like protein TAFA-3 (Q7Z5A8)
Organism: Homo sapiens (Human)
Function: Plays a role in the regulation of microglia polarization.
Subcellular location: Secreted {ECO:0000269|PubMed:15028294, ECO:0000269|PubMed:25595455}.
Interaction partners:
Sequence:
MSERVERNWSTGGWLLALCLAWLWTHLTLAALQPPTATVLVQQGTCEVIAAHRCCNRNRIEERSQTVKCSCFSGQVAGTTRAKPSCVDASIVLQRWWCQMEPCLPGEECKVLPDLSGWSCSSGHKVKTTKVTR
Protein: Transactivator/viroplasmin protein (Inclusion body matrix protein) (Q3HM11)
Organism: Cauliflower mosaic virus
Subcellular location: Host cytoplasm {ECO:0000256|ARBA:ARBA00004192}.
Interaction partners:
Sequence:
MENIEKLLMQEKILMLELDLVRAKISLARANGSSQQGDLPLHRETPVKEEAVHSALATFTPTQVKAIPEQTAPGKESTNPLMANILPKDMNPVQTGIRLAVPEDFLRPHQGIPIPQKSELNSTVAPLRAESGIQHPHINYYVVYNGPHAGIYDDWGCTKAATNGVPGVAHKKFATITEARAAADAYTTSQQTDRLNFIPKGEAQLKPKSFAKALTSPPKQKAHWLTLGTKRPSSDPAPKEISFAPEITMDDFLYLYDLGRKFEGEGDDTMFTTDNEKVSLFNFRKNADPQMVREAYAAGLIKTIYPSNNLQEIKYLPKKVKDAVKRFRTNCIKNTEKDIFLKIRSTIPVWTIQGLLHKPRQVIEIGVSKKVVPTESKAMESKIQIEDLTELAVKTGEQFIQSLLRLNDKKKIFVNMVEHDTLVYSKNVKDTVSEDQRAIETFQQRVISGNLLGFHCPAICHFIERTVEKEGGSYKCHHCDKGKAIIQDASADSGPKDGPPPTRSIVEKEDVPTTSSKQVD
Protein: NADPH-dependent ferric-chelate reductase (EC 1.16.1.9) (Ferric siderophore reductase) (Q46871)
Organism: Escherichia coli (strain K12)
Function: Plays a role in iron homeostasis under excess nickel conditions.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Transcriptional regulator YqjI
- Uncharacterized protein YncE
- Enterobactin synthase component E
- Enterobactin synthase component B
- Ferrienterobactin receptor
- Iron
- Uncharacterized protein YdiE
- Isochorismate synthase EntC
- Ferric enterobactin-binding periplasmic protein FepB
- Enterobactin synthase component F
Sequence:
MNNTPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDGFTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAIDFFIHDGGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLETLSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYFIWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK
Protein: Diphtheria toxin (EC 2.4.2.36) (Q6NK15)
Organism: Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Interaction partners:
Sequence:
MSRKLFASILIGALLGIGAPPSAHAGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYEYMAQACAGNRVRRSVGSSLSCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAGANYAAWAVNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIALSSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVHNSYNRPAYSPGHKTQPFLHDGYAVSWNTVEDSIIRTGFQGESGHDIKITAENTPLPIAGVLLPTIPGKLDVNKSKTHISVNGRKIRMRCRAIDGDVTFCRPKSPVYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQKTVDHTKVNSKLSLFFEIKS
Protein: Threonine dehydratase operon activator protein (P11866)
Organism: Escherichia coli (strain K12)
Function: Probable trans-acting positive activator for the tdc operon.
Interaction partners:
- HTH-type transcriptional regulator TdcA
- Probable fructoselysine utilization operon transcriptional repressor
- Pseudouridine kinase
Sequence:
MSKFSNFIINKPFSVINNAACHIFSRYLLENKHLFYQYFKISNTCIDHLEQLINVNFFSSDRTSFCECNRFP
Protein: CUE domain-containing protein 2 (Q9CXX9)
Organism: Mus musculus (Mouse)
Function: Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Progesterone receptor
Sequence:
MELERIVGSALLTFVQAHLPEADLSGLDEVIFSYVLGVLEDLGPSGPSEENFDMEAFTEMMEAYVPGFAHIPRGIIGDMMQKLSVQLSDARNKENLHPQSSCVQGQVPIFPETPRQAEKLEEESRPPAAPGNTLDEAAAAEELPGVDVLLEVFPTCSMEQAQWVLAKARGDLEEAVHMLVEGKEEGPPGWDGPSQDLPRRLRGPQKDDLKSFILQKYMMVDRAEDQKTHRPMAPKEAPKKLIRYIDNQVVSTKGERFKDVRNPEAEEMKATYINLKPARKYRFH
Protein: NEDD4 binding protein 2 (A0A0J9YUP5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDCLLELSATDAKGAESSAQTSGDRDSKPGAAGNSVMETCHPEGEGEDSKLDSFLDMQLTEDLDSLIQNAFEKLNSPPDDQVYPFSPLQDANSFNDPSTFMNSDSSGMTSLLSVQSTSSNSETLKSSASLPGSNPPTSHSVLNAPESCAKLALEGGYSEGSPLSSSGNPTNGSVRGCGNFSQRQKDLSESECPSAQHSQALADLGNSDPQAPSTHPLHNSGSDLPGTDGDQKSASAPDVFVPSEGFNFKPHKHPELPPKGKDMNYCPVLTPLPLLLPPPPPPPIWNPMIPAFDLFQGNHGFVAPVVTTAAHWRPVNYTFPPPIISHNSPTKVWRGGEGASAYQVQEAPASQPVRKKATSFVGLVLVLLRGLPGSGKSFLARTLQEDNPGGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKVSPVIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKISRMLEHYQRFVSVPIIMSSSDPEKTERIELCAYASDDSPRDSEAISSAKEDSVSSASPKHSELTEEKTLEVATQAVLSVRDPQLPCPGLNRGRKELGDVSHGGHNPFFQEAPSTYFPNPESKGQATDRSEEEQEMVSEKEHCEADAWRPAGGASSDGRCADDNQEACGSAGAAALPGETPSPPEMLEERTAGKKKTIGKQKGKSSLEKIPKQELSNFVGDWPVDKTISQRTKRNRKTEKGLSVQSDKKGNLPQSHKVLDARVSVNTDPVQPQGSSHGNDDLSEVPSSYHYDPYRSTEQSSLSAVSDWPSSASLAPREHRPRMPKADLSEPSVEFGTNDNLGEIPLYPAHEAYWGTSPEELKTLSSSLRSSEMLPSQTAPEHHPTSLNPLAHSQHALPLTFPSSAAALPGVVGPRSLTEFPVGVSGIVSGVDTGTCTQTEPQDFALLWKIEKNKINVSDSVRVLTGRLDGFKPKDFTLNRKVNVQETIPYRVMHDKSTFVEESELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTAVESSPKSYSESQVGPFSMGLDLKEIISHRGTSEGSNSSVSEFSPGIGIRNTSARSAGNPGKGTSEQEGRRAMNPENPELITRVFPNAAVKVKSNNETLPDRQAELPGAYTFKQPLSLTPRSYIPKDVSEIEKNLVMTETRDNMHSFLNLSDIINSATSTSNPELNEDVYLTGSLEVKKNENLPKDYVKFANMEEFINEDKQEMEKNLMPGSGWSAGVSEEGKAEVLTPTPVTATSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWRESVMERQRQEEVSRGKRTQDPLLAGHTGLDNFEQKSSQKTGKRLLKTLAAPETLDHWNTQTKKVSLREIMSEEIALQEKHDLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHSYSLENTVQFLNCVLEGDPVKTVVAQECVHQNENNTYTAQK
Protein: Synapsin-2 (Synapsin II) (Q92777)
Organism: Homo sapiens (Human)
Function: Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons (By similarity).
Subcellular location: Synapse.
Interaction partners:
- Synaptosomal-associated protein 25
- Synaptotagmin-1
- Disks large homolog 4
- Complexin-1
- Synapsin-3
- Vesicular glutamate transporter 1
- Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
- Vesicle-associated membrane protein 2
- Regulating synaptic membrane exocytosis protein 1
- Ras-related protein Rab-3A
Sequence:
MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSRTPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQGGPGQPQGMQPPGKVLPPRRLPPGPSLPPSSSSSSSSSSSAPQRPGGPTTHGDAPSSSSSLAEAQPPLAAPPQKPQPHPQLNKSQSLTNAFSFSESSFFRSSANEDEAKAETIRSLRKSFASLFSD
Protein: Probable UDP-3-O-acyl-N-acetylglucosamine deacetylase 5, mitochondrial (UDP-3-O-acyl-GlcNAc deacetylase 5) (EC 3.5.1.108) (Protein LIPID X C5) (AtLpxC5) (UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase 5) (F4IAW1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:21709257, ECO:0000305|PubMed:25732537}.
Interaction partners:
- Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, mitochondrial
- Probable UDP-3-O-acylglucosamine N-acyltransferase 2, mitochondrial
- Probable UDP-3-O-acylglucosamine N-acyltransferase 1, mitochondrial
- Probable lipid-A-disaccharide synthase, mitochondrial
- Probable 3-deoxy-D-manno-octulosonic acid transferase, mitochondrial
- Probable tetraacyldisaccharide 4'-kinase, mitochondrial
- Is a member of the PF|00364 Biotin-requiring enzymes family
- At5g19070
Sequence:
MRLPVTVKATKPSFLVIWIRYSSAASSPTVSLNPSGRLQQTLAGSVEVKGKSLHSGKFSTVKLNPEIAGAGRFFEFRSRFIPASIEFAQESPLCTTLLKDELKIRTVEHLLSALEAKGVDNCRIQIESESSDDREVEVPIFDGSAKEWVDAIQGVGINAAQNHDGESVEKMVAHVNKPVYVCKNDTFVAAFPALETRITCGIDFPQVPAIGCQWFSWRPIHESSFAKDIASSRTFCVYEEVERMREAGLIKGGSLDNAIVCSAEHGWMNPPLRFDDEACRHKILDLIGDLSLVSRGGNGGLPVAHIVAYKAGHALHTDLARHLTMD
Protein: GDP-mannose mannosyl hydrolase (GDPMH) (EC 3.6.1.-) (Colanic acid biosynthesis protein WcaH) (P32056)
Organism: Escherichia coli (strain K12)
Function: Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid.
Interaction partners:
- Putative colanic acid biosynthesis glycosyl transferase WcaI
- GDP-L-fucose synthase
- GDP-mannose 4,6-dehydratase
- Putative colanic acid biosynthesis glycosyl transferase WcaC
- Putative colanic acid biosynthesis acetyltransferase WcaF
- Putative colanic acid biosynthesis glycosyl transferase WcaE
- Putative colanic acid biosynthesis glycosyl transferase WcaA
- Putative polysaccharide export protein Wza
- Mannose-1-phosphate guanylyltransferase
- UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase
Sequence:
MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGLRLPITAGQFYGVWQHFYDDNFSGTDFTTHYVVLGFRFRVSEEELLLPDEQHDDYRWLTSDALLASDNVHANSRAYFLAEKRTGVPGL
Protein: Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP) (Q7TMR0)
Organism: Mus musculus (Mouse)
Function: Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH (By similarity).
Subcellular location: Lysosome {ECO:0000250}.
Interaction partners:
- Meprin A subunit alpha
- Angiotensin-converting enzyme 2
- Neprilysin
- Dipeptidyl peptidase 4
- Meprin A subunit beta
- Prolyl endopeptidase
- Plasma kallikrein
Sequence:
MGCRALLLLSFLLLGAATTIPPRLKTLGSPHLSASPTPDPAVARKYSVLYFEQKVDHFGFADMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFRKSGPYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWILDFYSNIQ
Protein: Vanillin aminotransferase (EC 2.6.1.119) (Putative aminotransferase) (pAMT) (O82521)
Organism: Capsicum chinense (Scotch bonnet) (Bonnet pepper)
Function: Participates in the biosynthesis of capsaicinoids in pungent cultivars of Capsicum chinense. Capsaicinoids, the alkaloids responsible for the heat or pungency of chili pepper, are synthesized from phenylpropanoid intermediates in the placental tissue of chili peper fruit (Probable). Can transfer an amine from vanillylamine to pyruvate forming vanillin and L-alanine. Can use pyruvate or oxaloacetate, but not 2-oxoglutarate as amino group acceptors. Is able to convert (S)-1-phenylethylamine into acetophenone in vitro.
Interaction partners:
Sequence:
MANITNEFMGHDMLAPFTAGWQSDMEPLVIEKSEGSYVYDINGKKYLDTLSGLWCATLGGSETRLVEAANKQLNTLPFYHSFWNRTTKPSLDLAKELLNMFTANKMAKVFFTNSGSEANDTQVKLVWYYNNALGRPQKKKIIARAKAYHGSTYISAGLSGLPPMHQKFDLPPPFVLHTECPHYWAYHLPGETEEEFSTRLANNLESLILKEGPETVAAFIAEPVLGAAGVILPPATYFDKVQTILRKYDILFIADEVVCGFGRLGTMFGGDKYNIKPDLVSVAKALSSGYMPIAAVLVSQKISSVILSESNKIGAFCHGFTYSGHPVACAVALEALKIYKERNITEVVNKISQKFQEGLKAFADSPIIGEIRGTGLALSTEFVDNKSPNDPFPYEWAVGTYFGAQCAKYGMLVSSTGDHVNMAPPFMLSLEELDELIRIYGKALKDTEKRVEELKSQKK