wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial adenyl nucleotide antiporter SLC25A24 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Short calcium-binding mitochondrial carrier protein 1) (SCaMC-1) (Solute carrier family 25 member 24) (Q6NUK1)
Organism: Homo sapiens (Human)
Function: Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation of calcium-phosphate precipitates in the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:15054102, ECO:0000305|PubMed:15123600, ECO:0000305|PubMed:22015608}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- NADH-ubiquinone oxidoreductase chain 3
- NADH-ubiquinone oxidoreductase chain 1
- NADH-ubiquinone oxidoreductase chain 4
- NADH-ubiquinone oxidoreductase chain 2
- NADH-ubiquinone oxidoreductase chain 5
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- ADP/ATP translocase 1
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase iron-sulfur protein 2, mitochondrial
Sequence:
MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK
Protein: Interferon gamma (Q4TWG0)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
QGPFFKEIENLKEYFNASNPDVAKGGPLFSEILKNWKEESDKKIIQSQIVSFYFKLFENLKDNQVIQRSMDIIKQDMFQKFLNGSSEKLEDFKRLIQIPVDDLQIQRKAINELIKVMNDLSPKSNLRKRKRSQNLFRGRRASM
Protein: COX assembly mitochondrial protein 2 (Cx9C motif-containing protein 2) (Mitochondrial metallochaperone-like protein CMC2) (Q3E7A4)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. May be involved in copper trafficking and distribution to mitochondrial COX and SOD1.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:19703468, ECO:0000269|PubMed:20220131}; Peripheral membrane protein {ECO:0000269|PubMed:19703468, ECO:0000269|PubMed:20220131}; Intermembrane side {ECO:0000269|PubMed:19703468, ECO:0000269|PubMed:20220131}. Mitochondrion intermembrane space {ECO:0000269|PubMed:22984289}. Note=Imported into the mitochondria via the mitochondrial MIA40-ERV1 machinery.
Interaction partners:
- Cytochrome c oxidase assembly factor 6
- Cytochrome c oxidase-assembly factor COX23
- Cytochrome oxidase assembly factor 4
- mRNA-binding protein PUF3
- Cytochrome c oxidase copper chaperone
- Cytochrome c oxidase assembly protein COX11
- Uncharacterized protein YPR063C
Sequence:
MHPQLEAERFHSCLDFINALDKCHQKEYYKRIFGLCNNEKDALNKCLKEASLNNKKRAVIESRIKRADVEKRWKKIEEEEYGEDAILKTILDRQYAKKKQESDNDANSK
Protein: Chemotaxis protein CheY (Q51455)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY is likely to be involved in changing the direction of flagellar rotation.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Protein phosphatase CheZ
- Flagellar motor switch protein FliM
- Chemotaxis protein CheA
- Chemotaxis protein CheA
- Probable purine-binding chemotaxis protein
- Flagellar motor switch protein FliN
- RNA polymerase sigma factor FliA
- protein-glutamate methylesterase
- Probable chemotaxis protein
- Protein PilH
Sequence:
MKILIVDDFSTMRRIIKNLLRDLGFTNTAEADDGTTALPMLHSGNFDFLVTDWNMPGMTGIDLLRAVRADERLKHLPVLMVTAEAKRDQIIEAAQAGVNGYVVKPFTAQVLKEKIEKIFERVNG
Protein: Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) (Q9H1V8)
Organism: Homo sapiens (Human)
Function: Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity).
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:P31662}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P31662}. Postsynapse {ECO:0000250|UniProtKB:Q8BJI1}. Presynapse {ECO:0000250|UniProtKB:Q8BJI1}. Note=Localizes at synaptic junctions - at both pre- and post-synaptic sites - particularly in excitatory glutamatergic terminals. {ECO:0000250|UniProtKB:Q8BJI1}.
Interaction partners:
- Ubiquitin-like protein 4B
- Homeobox protein aristaless-like 3
- Testis-expressed protein 15
Sequence:
MPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVVRNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSRDLIPPHVNFSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVVATLPIPVVFVLRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLASTPESEL
Protein: Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (Poly ADP-ribose metabolism enzyme 1) (Protein poly-ADP-ribosyltransferase parp-1) (EC 2.4.2.-) (Q9N4H4)
Organism: Caenorhabditis elegans
Function: Poly[ADP-ribose] polymerase modifies various nuclear proteins by poly(ADP-ribosyl)ation, a post-translational modification synthesized after DNA damage that appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks and programmed cell death. Involved in protection of the genome against mutations.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00397}.
Interaction partners:
- Poly [ADP-ribose] polymerase 2
- Poly
- Poly
- Zinc finger, CCHC-type
- XPA C-terminal domain-containing protein
- Ku domain-containing protein
- XPC
- Methylated-DNA--protein-cysteine methyltransferase
- Uracil-DNA glycosylase
- AlkylGuanine DNA alkylTransferase
Sequence:
MIHSNEPLPYAIEYAKSGRSNCKTCKKNIALDQLRMSMNRPSTFFDGNMDSWFHYNCFWIKMIRGRDDINISSIRGVDWLRWEDQEKLRQEIQHFKTASPPTLTPLCSTTTVILSTIKTEKSLSNRGKCGKCGQNFERGEIKAHNKGKANHFKCFLQEFDKISGTVEDIPGWADYEENFKIKAVGEYVEALAAKRRSTEPATPASASPTPPEAETPVLSAEGSPESSNKRPASSEIIEIDGEGNPDENDFAKKRRMKKEARLMEVQKKRMKKQSDLLWEYRQIFERMPYTDKISILRENEQDIPEGHDPTAQVIERLVDNALFGCPIICQTCSNGKIVYNSSCRTYVCTGYATEYSKCTYESKNPIRTPFEVSHRLTEKHKLQDIVFNQMSERLYIGEEDGESVVKIDKRKSKGGTRGEQFIYAAEAFDSTNNVPIKVGDLTSTNTHIIKKGTVVDAKFALADRCHVFKNEIDGSLYQATLSFTDLTQNKNSYYKIQLLKDDQRENYYVFRSWGRVGTEVGGNKHESYSNSNEAILKFQDVFHEKTKNDWIYRKHFRKMPGMFSYVETDYSEFAQITDTEITPGSKTLLPKSVKEVVMSIFDVENMKSALKSFEMDVNKMPLGRLSHNQINLAFEVLNDISDLLVKLPIDASRILDFSNKFYTIIPHNFGMRVPEPIDSFHKIKEKNNMLNALLDIKFAYDQISGGDVPASTSLGIDPVDINYQKLKCIMEPLQQGCDDWNMIHQYLKNTHGATHDLKVELIDILKLNRDNESSKFKRHIGNRRLLWHGSGKMNFAGILGQGLRIAPPEAPVSGYMFGKGVYFADMFSKSFFYCRANAKEEAYLLLCDVALGNVQQLMASKNVSRQTLPAGFQSVQGLGRQCPREIGSYNHPDGYTIPLGLTYMQLQGKQDVDYHLLYNEFIVYDVDQIQLKYLVRVKMHHARHL
Protein: Cytosolic Fe-S cluster assembly factor NUBP2 homolog (Q57WQ0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_03039}.
Interaction partners:
Sequence:
MATSLSDVNHIILVLSGKGGVGKSTVACQLALALANVHGKKVGLLDVDICGPSVPTICGVTGKDVYRGDAGWEPVSLFHEQHEADTAASATGNVKIMSIAFLLPSENDAVVWRGPKKDAMIRQFVTDVHWGALDYLIIDTPPGTSDEHLTLCEVLKPFNTAGAVIVTTPQDVATDDVKKELSLCHKLELRCLGVVENMSGFVCPHCAHCTDIFSKGGGKKLAEMYEVEFLGAIPIDPTLSLAEDKGQCFVTTATDANSPTVRKTVAAVTGVIDAILKQVEKSAQLQQRH
Protein: Carboxypeptidase M14B (Carboxypeptidase MCPB) (Q5AX59)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MGATTTGLILGLASLASAVTYGYNHVPVTKDSETVAGAFANVDDIQLRSPAFLTPDARLPGFTNGTQGPSSQDDLEEFLEQLVGRNDYMTYGTANFTSQEHRSFPYVHLSASHSSSVRRGNSSSKVRVWIQGAVHGNEPAGDETTQALLGKFDDDPEWAASILDKLELVILPRYNPDGVFYFQRTLATNIDPNRDHIKLASQQTRDIKQFMNTFNPHVIVDMHEYSASRPYGGGRYVHGSDGLFSAAKNLNINEEIRKLSEELFAKNIADDMKAAGLRAEPYVTGTSVSNSSIVADFAEAGTDSKIGRNAMGLTQAVVFLLETRGIGIADQEFQRRTAAGLTMLGSIVQTAADNAEEVFTTVEDGIERFIKSADDIVVTDYSEIKIRPFTMVDKENGSVVHPSVRFASTTPSFANLTRARPEAYLIPPAWAHLAERLRVAGCEVETLDKPFDGVVEALTITSAEIDSSYYEGVIRVTATTESSERELSLPEGSFRVSTRQKNAALAMVALEPENIDSYVSFNIVPVEEGDEYPVFRIMSSK
Protein: Co-chaperone protein p23 (F4J2B8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369032}. Nucleus {ECO:0000256|RuleBase:RU369032}.
Interaction partners:
Sequence:
MCDRYRFKGFNICLLKSIAVFLHPPFIIPAPFIQNLHLAENMSSKLRIFVIDIRMIRNPEVLWAQRSDKVYLTVALPDAKDISVKCEPQGLFSFSALGAQGERFEFSLELYGKIMTEYRKNVGLRNIIFSIQKEERSWWTRLLKSEEKPAPYIKVDWNKWCDEDEEVNSETASDDESAFVNQDSESSDDDGLLYLPDLEKARNK
Protein: Enhancer of zeste 1 polycomb repressive complex 2 subunit (K7EIH5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQSMKPVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEEGHNDTSDGKQDDSKEDLPVTRKRKRHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAK
Protein: Cyclic AMP receptor 2 (cAMP receptor 2) (P34907)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Receptor for cAMP. Coordinates the aggregation of individual cells into a multicellular organism and regulates the expression of a large number of developmentally regulated genes. The activity of this receptor is mediated by G proteins. Plays a key role during tip formation and late development; involved in cAMP-directed patterning of pre stalk cells as they sort before and during tip formation.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein alpha-2 subunit
- Adenylate cyclase, aggregation specific
Sequence:
MTIMSDIIAQRTILLIADFSSIIGCSLVLIGFWRLKLLRNHITKIISLFCATSLFKDVISTIITLLYKPDQTESGFPCYLHAIVITFGSLACWLWTLMLSFSIYNLIVRREPEPERFEKFYFCLCYGLPLISTIVMLSTHIIQPVGGWCWIGDNYDGYRFGLFYGPFFFIWGTSAILVGLTSKYTYSVIRSSVSDNKDKHMTYQFKLINYIVVFLVCWVFAIVNRILNGLNQFPTVPNVLHTYFSVSHGFYASITFIYNNPLMWRYFGAKFLLIFSKFGLFVQAQQRLELNKNNNNPSPIMRSKNALDNGADSSVVELPCLSKADSLSLDAENNIETPKENENQNHHHHHHHHHHHNHYNNNNNNNNINNKNDMI
Protein: Transcription factor MafA (Pancreatic beta-cell-specific transcriptional activator) (D3ZNT6)
Organism: Rattus norvegicus (Rat)
Function: Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1 (By similarity). Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:15665000}.
Interaction partners:
Sequence:
MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGSSAGGGGSAAQAGGAPGPPSGGPGTVGGASGKAVLEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHSAHHGAHHPAAAAAYEAFRGQSFAGGGGGGADDMGAGHHHGAHHTAHHHHSAHHHHHHHHHHGGSGHHGGGAGHGGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPREPSPAQAGPGAAKGAPDFFL
Protein: tRNA pseudouridine synthase 4 (EC 5.4.99.25) (tRNA pseudouridine(55) synthase) (Psi55 synthase) (tRNA pseudouridylate synthase 4) (tRNA-uridine isomerase 4) (O59721)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. Also catalyzes pseudouridylation of mRNAs with the consensus sequence 5'-GGUUCRA-3'.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P48567}. Mitochondrion {ECO:0000250|UniProtKB:P48567}.
Interaction partners:
- Putative tRNA pseudouridine synthase C16C4.06c
- Nucleolar protein 56
- tRNA
- Pseudouridylate synthase C18B11.02c
- H/ACA ribonucleoprotein complex subunit nhp2
- Nucleolar protein 58
- Multisubstrate pseudouridine synthase 7
- H/ACA ribonucleoprotein complex subunit gar1
- rRNA 2'-O-methyltransferase fibrillarin
- tRNA
Sequence:
MTVTNTYNPTLFFTRVVFQRITKFTAKANEENEILFYALFVADLCLDMKGGLIAINKPSGRTSAQCLNELKKIISNSELAQYFRPAPPHPNDRNRRRRKSNRLPDIKIGHGGTLDPLASGVLVVGLGTGTKQLSSLLSCMKTYRATALFGCSTDTYDSAGKIIKIAVHIPTKEEILSGLDAFRGDISQLPPLYSALHIQGKRLYEYAREGIPLPESIKARSMHCEELILKDFIPKEEHTYTDPDEFASKEAIESEELLRPIEGGAERHDLLAKTEQDINPQDGDEKINAKSPTTNSVTDVAKDQTVTNPKKRKFEVTDLARGSRPAIGPIAVLDMTVSSGFYVRSLIHDLGRQVNSEAHMVDLVRLKQGSFALDDENCFDFSEFSAPGWEEKLAAAFKIDLKGDETS
Protein: Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Q8VDM6)
Organism: Mus musculus (Mouse)
Function: Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Also plays a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Nuclear RNA export factor 1
- mRNA export factor
- Heterogeneous nuclear ribonucleoprotein L
- NTF2-related export protein 1
- Heterogeneous nuclear ribonucleoprotein M
Sequence:
MDVRRLKVNELREELQRRGLDTRGLKAELAERLLAALEAEEPEDERELEADDDPGLPGHNNEEVETEGGSELEGTAQPPPPGLQPHPEPGGYSGPDGHYVMDNITRQNQFYETPVIKQENESSYDRRPLDMEPQQQVYHPELKTEMKQEAPPSFLPPEASQLKTDRPQFQNRKRPFEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTIGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTVKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFDSRGGGFRGRGGGGGFQRYDNRGPPGGNRGGFQNRGGGGGSGGGGGNYRGGFNRSGGGGYNQNRWGNNNRDNNNSNNRGNYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASSYNKNSNIPGSSANTSTPTVSSYTPPQPSYSQPPYNQGGYTQGYTAPPPPPPPPPAYNYGSYGPYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWSQYYQNQSQWPPYYGNYDYGGYSGSTQGGTSTQ
Protein: Protein CWH43 (Calcofluor white hypersensitive protein) (P25618)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the maintenance of cell wall integrity. Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation.
Subcellular location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Concentrates to the bud tip of small budded cells and to the neck of dividing cells.
Interaction partners:
- Mannosyl-oligosaccharide glucosidase
- Uncharacterized protein YCR099C
- Dolichyl-phosphate-mannose--protein mannosyltransferase 2
- Protein PER1
- Protein TED1
- Membrane-bound O-acyltransferase GUP1
Sequence:
MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYPDEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPMIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSFFQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFLFWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLPFVSEAFTQYGVLLGGIIAIGAYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETSFSFALTWLLGLVASVILKMGFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKLFLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVKFMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQNIWVYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQLVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDSQLITAGIWTIHFGLDNDMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKHTWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDRRLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYILYRGLRRTGYARVARGTITDTELQVGKFQVLSEQALVEHSDSMYEYGHMSEPEYEDMKFPDKFLGEGERGHFYHVFDEPRYYL
Protein: Solute carrier family 25 (Mitochondrial deoxynucleotide carrier), member 19, isoform CRA_a (cDNA FLJ40563 fis, clone THYMU2004169, highly similar to Mitochondrial deoxynucleotide carrier) (Q5JPC1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCMNRTASQR
Protein: Kleisin alpha (A0A1D8PU88)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Irr1p
- Structural maintenance of chromosomes protein
- Structural maintenance of chromosomes protein
- Pds5p
- Sister chromatid cohesion protein
- Serine/threonine-protein kinase
- separase
- Mitosis inhibitor protein kinase SWE1
- Structural maintenance of chromosomes protein 5
- N-acetyltransferase ECO1
Sequence:
MIPDSIISKQGPLGHVWLAANYDKKLTKQQLMNTSIVKSTEYIANHPVITNVSVSQELPSDLDSTNTITLRLSGQLLLGIVRIYSRKTKYLLDDVNDILYKLKASFKLSSGVNLGSDNISNQVNLPPEQTILQNLNSIILKDQVTSANLLQQDDLDLSDIHGTSTGSGLDGMLNHNASQSSSEYSEYDNSIEFPRYEEEAAAPGHTEDFELDFDLNLDDDNSIEYGRDASVSINDREISIISDVHKERTTGDIFDLNFGQPLDDLNDDEAENEEDRQLPSNSEHQERSAESDLQPRRVRQKRTRITEDGQIITNNRKLVVDSEEAMEGLAIQQLKDNQEKILSGQDSAPYISLNLSDFEKLKLIEELAVPVATKKRKLWNLNAELQYRCAELALQEQQQHQQYEENNQQNDFHLDQSFDNDSMDFDLSLPDFDDQHSDNFSDAGILDDEVDEEDDTNYTHTARVTEQIGQELIELFKSSNTVEFEKLIETDSEIHHRNPDKLPLGVVSKNKDRINSRKEATKCFFELLVLATNNCISLGQIPQETTIAGDISITSRDRLFSQFV
Protein: AB hydrolase-1 domain-containing protein (Q2H2M9)
Organism: Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
Interaction partners:
- Tryptophan synthase
- Homoserine dehydrogenase
- Cystathionine beta-synthase
- cystathionine gamma-synthase
- Cystathionine gamma-synthase
- Cystathionine gamma-synthase
- alanine--glyoxylate transaminase
- Threonine dehydratase
- Cystathionine gamma-synthase
- L-serine ammonia-lyase
Sequence:
MTPDSVQNGPRPVYERIHSQPENPFAELIPHQQIAVIPSFTLESGVTLSNVPVAYTTRGTLSPDADNVMVICHALTGSADVGDWWGPLLGGPGRAFDTSRFFVVCMNSLGSPYGTASPVTAKDGDPSKGRYGPEFPLTTIRDDVQLHKLLLDELGVKQVAAVIGGSLGGMFVLEWAYFGKDYVRCIVPIATSSRHSAWGISWGEAQRQSIYADPKYEDGYYSFSDPPSTGLGAARMAALLTYRSRNSFEARFGRNIPDPSRRQTIRERPTPSTPSEAHFHTHNDGHKWTRSPSRKNSDGEQAPKYDQGGDASLDPQFHGPKNGSLTGGEVMPTSSTYFSAQSYLRYQGGKFVKRFDSNCYIAMTRKLDTHDVSRGRAGTIAEALAMIEQPTLVLGIESDGLFTFAEQEELAQHIKNARLERIDSPEGHDAFLLQFEQVNHYTLDFLREALPDIMNKNTNGVAVESSVGELTKSSTFGEAEVEDITAW
Protein: Tubby protein homolog (P50607)
Organism: Homo sapiens (Human)
Function: Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Secreted {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Binds phospholipid and is anchored to the plasma membrane through binding phosphatidylinositol 4,5-bisphosphate. Is released upon activation of phospholipase C. Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). {ECO:0000250}.
Interaction partners:
Sequence:
MTSKPHSDWIPYSVLDDEGRNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVESYLSSSGSTSYQVQEADSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHKGTSGPAALAEDKSEAQGPVQILTVGQSDHAQDAGETAAGGGERPSGQDLRATMQRKGISSSMSFDEDEEDEEENSSSSSQLNSNTRPSSATSRKSVREAASAPSPTAPEQPVDVEVQDLEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKTSNYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAAVCYETNVLGFKGPRKMSVIVPGMNMVHERVSIRPRNEHETLLARWQNKNTESIIELQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCALQAFAIALSSFDSKLACE
Protein: Large ribosomal subunit protein uL11 (50S ribosomal protein L11) (O51354)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
Interaction partners:
- Large ribosomal subunit protein bL17
- Translation initiation factor IF-1
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein bL33
- Large ribosomal subunit protein uL6
- Large ribosomal subunit protein bL21
- Large ribosomal subunit protein bL27
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein bL19
- Large ribosomal subunit protein uL16
Sequence:
MAKKKAISWIKLQVPAAQAAPGAKIGQALGPHGVSGPQFVKEFNERTAKMDPGIVVPVIITVYSDKSFSFIVKTPPASILIKKAIGIESGSKKSNTDKVGTISKEKLMEIARIKMSDLNAKSESAAFKIIAGSARSMGVEVEK
Protein: Choline/carnitine acyltransferase domain-containing protein (Q384I9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSKKKGSKLNAAANSTTDIKGLNFCSVKEYGQFNSNEYKIFVAPNRPLQSRLVNLNSLRPHGAVGSAELRSRFHSHPVPENVVKDILTLVNDAQSRVHRCPDFTLVTSVREAMESLHSTAYEQWWMDHIAKGCLSTNAYPFSSLRFAAPHENSQGCSMNSNSSVPDSLSGIAEAIQRILFVCTQSSNNGDQATEKLLFHSIRNEKASLKELVLTSYNSNHILVCCGLYFYRLNVLDENGVAINVGDITSLLRAVKEHAEATEKALREQLLLPDVMNDLVQFHHMLGYMSEIANPECAALMDRLRRANSVNAAALDIMDSSIFTVVLRNPCEAGSPRARWYRTGMLLEEDDDGRLLTLRAHTIITDHTSLVDFLTQVINWRDEHERLGRSSCLLGKTKDEYFVSTPNEPAMIEHLNLWLPWKHRKPMWPYPQKNAMPSVFPLEFTTLGEGVVTFSCLCLAAVLAVQEVLTPSHGFPTVLVAFPHKRGGVSSALLYSKVVEAFIQSLRSESALVEAVTVRHMARAALQALNTIINACFSEQYPLYTMAQLLLSEGKAEAKDATHDGGMLGAVDLVLSIDPLSCGGDILHSETQLVMPTPFAIRSVGRCTPGAARQQTNVKLPSALEVTDAALLQMPGAGESSTGRRLSACILERSQVLLTLLK
Protein: Homeobox-leucine zipper protein HAT14 (Homeodomain-leucine zipper protein HAT14) (HD-ZIP protein 14) (P46665)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeobox-leucine zipper protein HAT22
- Homeobox-leucine zipper protein HAT3
- At4g33960
Sequence:
MELALSLGDNTKKQFSFMEKNSKINNPSVSSTSTSEKDLGFCMALDVAFGGHRSLSSSSSPSVEDEKKKPAPRAKKSDEFRVSSSVDPPLQLQLHFPNWLPENSKGRQGGRMPLGAATVVEEEEEEEEAVPSMSVSPPDSVTSSFQLDFGIKSYGYERRSNKRDIDDEVERSASRASNEDNDDENGSTRKKLRLSKDQSAFLEDSFKEHSTLNPKQKIALAKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLKRCCESLTEENRRLQKEVKELRTLKTSTPFYMQLPATTLTMCPSCERVATSAAQPSTSAAHNLCLSTSSLIPVKPRPAKQVS