wanglab/gogpt-training-data huggingface dataset:
Protein: Antimicrobial protein AN5-1 (B3EWQ6)
Organism: Paenibacillus alvei (Bacillus alvei)
Function: Has bactericidal activity against E.coli ATCC 29522 and S.aureus. Inhibits growth of S.marcescens and B.cereus ATCC 14579. A synthetic peptide has antibacterial activity against E.coli ATCC 29522 (MIC=8 ug/ml), S.aureus (MIC=64 ug/ml), S.marcescens (MIC=32 ug/ml), B.cereus ATCC 14579 (MIC=64 ug/ml), B.subtilis (MIC=32 ug/ml), L.plantarum ATCC 8014 (MIC=32 ug/ml), B.flexus (MIC=32 ug/ml), S.enteritidis ATCC 13076 (MIC=4 ug/ml), Enterobacter spp (MIC=32 ug/ml), B.anthracis (MIC=128 ug/ml), B.licheniformis (MIC>128 ug/ml) and L.lactis ATCC 11454 (MIC>128 ug/ml).
Interaction partners:
Sequence:
YSKSLPLSVLNP
Protein: Chaperone DnaJ-domain superfamily protein (Q9FK56)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At1g77930
- Chaperone DnaJ-domain superfamily protein
- Methyl-coenzyme M reductase II subunit gamma, putative
- Heat shock protein DnaJ with tetratricopeptide repeat-containing protein
- Heat shock protein DnaJ with tetratricopeptide repeat-containing protein
- At2g17880
- At3g13310
- Chaperone protein dnaJ C76, chloroplastic
- At2g42750/F7D19.25
- NifU-like protein 3, chloroplastic
Sequence:
MQTHLLVGPIPLKGYRRFSSSSFSGDLLPPSSNPIGRDLFPHRRRHRDGKSRSYRNRSKTTITSAAFSSSSNTGGQNHYAVLGIARNATQGDIKRAYRLLARKFHPDVNKDSKAGELFKSVRCSYEVLSNEATRTQYDRALKLQENSRFHRVKRHSYTPEVEDAMKYYYTWSEKRQRSRHGRFYGHYSTYPNSHFYAETEPQEEEGVETAPDQRDSFVEALKSAFLSMFLLYTFGCLASLTFSTFTALLDKELDMGYKVGFMIAWILGGKGGILLTLCLTFASWLCGKASSSVVVLVLVAMWVGSNLARHAPLPQGALLTLLYMSIKLQVDST
Protein: Disease resistance-like protein DSC2 (EC 3.2.2.6) (Protein DOMINANT SUPPRESSOR OF CAMTA3 NUMBER 2) (F4JWM0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: TIR-NB-LRR receptor-like protein involved in plant defense. Acts as a trigger of hypersensitive response (HR). Functions as guard of CAMTA3, a negative regulator of immunity, during pathogen infection.
Interaction partners:
- Heavy metal-associated isoprenylated plant protein 43
- Heavy metal-associated isoprenylated plant protein 33
- Heavy metal-associated isoprenylated plant protein 6
- Protein RESTRICTED TEV MOVEMENT 3
- Heavy metal-associated isoprenylated plant protein 14
- MD-2-related lipid-recognition protein ROSY1
- Obg-like ATPase 1
- Eukaryotic initiation factor 4A-3
- Protein VASCULAR ASSOCIATED DEATH 1
Sequence:
MAIAEVIGFFTLVCVIWYWVYKKHKNLQLKICRSSIESSSSSSSLSSPPSLSSPISRTWTHQVFPSFRGEDVRKGFLSHIQKEFKSKGIVPFIDDEMKRGESIGPGLFQAIRESKIAIVLLSKNYASSSWCLNELVEIMNCREEIGQTVMTVFYQVDPSDVRKQTGDFGKAFKKTCVGKTQEVKQRWSRALMDVANILGQDSRKWDKEADMIVKVAKDVSDVLSYTPSRDFDDYVGIRPHITRINSLLCLESSDVRMIGILGPPGIGKTTIARVLYDQISEKFQFSAFIENIRLSYWKGWHDEGNLDFPVEIMTGDRQRKLNLQRRLLSELFNQKDIQVRHLGAVQERLRDHKVLVILDGVDQLEQLTALAKETQWFGYGSRIIITTQDQRLLRAHEINHVYKVDLPATDEALQIFCLYAFGQKFPYDGFKKLAREFTALAGELPLGLRVLGSYLRGMSLEEWKNALPRLRTSLDGEIEKTLRFAYNVLSDKDKSLFLHIACLFNGCQVNHVKQWLANSSLDVNHGFEVLSNKSLISTDMGLVRMHSLLQQLGVDIVRKQSIGEPEKRQFLVDVNEISDVITDNTGTGTILGIMLHVSKIEDVLVIEETVFDRMTNLQFLILDECLRDKLNLPLGLNCLPRKIRLLRWDYCPLSIWPSKFSAKFLVELIMRANKFEKLWEGIQPLKNLKRMELGDARNLKEIPDLSNATNLESLLLSFCTSLLEIPSSIRGTTNLKELDLGGCASLVKLSSCICNATSLEELNLSACSNLVELPCALPGDSNMRSLSKLLLNGSSRLKTFPEISTNIQELNLSGTAIEEVPSSIRLWSRLDKLDMSRCKNLKMFPPVPDGISVLNLSETEIEDIPPWVENLSQLRHFVMIRCKKLDNISLSRISKMEGVHCLQITRGDEDVSGDSIVNIRWYSNFPNQWTLQSDMLQICLPELVYTSPVSLHFISNEFKTIPDCIKNLSQLHQLSFYRCHKLVSLPQLSDCLSSLDAENCVSLETIDGSFHNPDIRLNFLNCNNLNQEARELIQKSVCKHALLPSGEVPAYFIHRAIGDSVTIHLKERHLPLYLIFKASLVLFNDDEINYDYDDDDDDDYDEEVIVYGDYDSYPHSDDYTKQETMRLSCRVEGKQNGLTIQYGSSVHLLPTPHRYTEHVYIFEASFSLGECNSPEAESELVFDFKVHDYFWAIKECGLRLLELPHAHGDD
Protein: Nuclear distribution protein nudE homolog 1-B (Q6NRJ5)
Organism: Xenopus laevis (African clawed frog)
Function: Required for centrosome duplication and formation and function of the mitotic spindle.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Cleavage furrow {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9NXR1}. Note=Localizes to the interphase centrosome and to the mitotic spindle. {ECO:0000250}.
Interaction partners:
Sequence:
MDDLENIIFNSVEEEIIYWKSVAMKYKQCSEEAQQELQEFQEASREYEAELEAQLQQTEGRNRDIFSENNRLRMELDSIKEKYEEQHSENYIQISTLEGDLSTTKAVRDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENVLESVQRLKDEARDLRQELAVQQKQEKPKSNMVSPETERMDTSVQASIAIPLAPLTPLSQRGCASTLNSPLSFKTSWDDGYSGTPLTPCARISALNIVGDLLRKVGALESKLASCRNFVHEQSPNRPLTSVSARMNKTREGIENRLSIASGSSVEKGLIKRLEFGSLPSNTPMQGMRSPQGVVKIII
Protein: Expressed protein (Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein) (Q9SJH9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MDALGGCGGAGGFWGWNGFDQRRKKKSSGDRGKKRNSGSSDSVDVSRDAGGYRFPLKQAVTAGALTFTGDTIAQLSGRWKKRTALKQSSSELDEGELWNIFSEHDWIRALRMSSYGFLLYGPGSYAWYQFLDHSLPKPTATNLVLKVLLNQVILGPSVIAVIFAWNNLWLGKLSELGNKYQKDALPTLLYGFRFWVPVSILNFWVVPLQARVAFMSMGSVFWNFYLSSTMSK
Protein: Aspartate-glutamate racemase family (F9L1.36 protein) (Q9XI28)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Pentatricopeptide repeat-containing protein At1g71460
- Trimethylguanosine synthase
- Uncharacterized aarF domain-containing protein kinase At5g05200, chloroplastic
- Transducin family protein / WD-40 repeat family protein
- Formate dehydrogenase, chloroplastic/mitochondrial
- RNA-binding
- Uncharacterized protein
- Pentatricopeptide repeat-containing protein At2g40240
- FAD/NAD
- Glyoxylase I 4
Sequence:
MYLQIFNNPSHGLAHLCYSSRVSCRVRLSRVLAMPPSSVLLHMDESNDLPKPKKGFCLSEDSRNSLNSLPADSLLRQANTVGIIGGVSTDSTLKFVKKLVDWSSNDGKSSLPFVLCSDPALNKELLLYEENSYPSLYHREESTPVDPKLIVENLRNKRRYLERCGAKLILMPCHIAHIWYEEVCEGSLVPLLHMGECIAKELQEAKMKPLEAGNPLRVGVMATSATLSAGFYQEKLQSNGFEAVLPDKATMEHTVIPSIEAMKRKDMEGARNLLRIALQVLLVQAVNVVMLGSDEMRDLLPGDDPLLKKCVDPMDALARSAIKWAENRCS
Protein: Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) (Q9NSD9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000305|PubMed:29573043}.
Interaction partners:
- Phenylalanine--tRNA ligase alpha subunit
- Phenylalanine--tRNA ligase, mitochondrial
- Tyrosine--tRNA ligase, cytoplasmic
- Ferredoxin-fold anticodon-binding domain-containing protein 1
- Elongation factor 1-beta
- Bifunctional glutamate/proline--tRNA ligase
- Isoleucine--tRNA ligase, cytoplasmic
- Calcium load-activated calcium channel
- Leucine--tRNA ligase, mitochondrial
- Leucine--tRNA ligase, cytoplasmic
Sequence:
MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKEIISKEQGNVKAAGASDVVLYKIDVPANRYDLLCLEGLVRGLQVFKERIKAPVYKRVMPDGKIQKLIITEETAKIRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIENKPLYPVIYDSNGVVLSMPPIINGDHSRITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEYCENQFTVEAAEVVFPNGKSHTFPELAYRKEMVRADLINKKVGIRETPENLAKLLTRMYLKSEVIGDGNQIEIEIPPTRADIIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGVDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEISDIVIKDSNTDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGEDKGGYVIKASEGPAFFPGRCAEIFARGQSVGKLGVLHPDVITKFELTMPCSSLEINVGPFL
Protein: Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16) (Q9H9F9)
Organism: Homo sapiens (Human)
Function: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:18026119, ECO:0000269|PubMed:18163988, ECO:0000269|PubMed:19014934}. Cytoplasm {ECO:0000269|PubMed:19014934}. Note=Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses (PubMed:18163988).
Interaction partners:
- RuvB-like 1
- INO80 complex subunit E
- INO80 complex subunit C
- Nuclear factor related to kappa-B-binding protein
- Chromatin-remodeling ATPase INO80
- RuvB-like 2
- INO80 complex subunit B
- Actin-related protein 8
- Ubiquitin carboxyl-terminal hydrolase isozyme L5
- Actin-like protein 6A
Sequence:
MAANVFPFRDARAAPDPVLEAGPVAHGPLPVPLVLDNGSFQVRAGWACPGQDPGPEPRLQFRAVCARGRGGARGASGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPKNSMCSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILHEHSYIAEDYVEELHKWRCPDYYENNVHKMQLPFSSKLLGSTLTSEEKQERRQQQLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLSIAVEQAKQKILQAEVNLEVDVVDSKPETPDLEQLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLQYILDRYPKDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSSFQVQLASNPVLDAWYGARDWALNHLDDNEVWITRKEYEEKGGEYLKEHCASNIYVPIRLPKQASRSSDAQASSKGSAAGGGGAGEQA
Protein: Protein trachealess (Q24119)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor, master regulator of tracheal cell fates in the embryo, necessary for the development of the salivary gland duct, Malpighian tubules and the posterior spiracles. It may induce a general fate of branched tubular structures of epithelial origin. Functions with tgo to regulate expression of btl.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:11740943}.
Interaction partners:
- Aryl hydrocarbon receptor nuclear translocator homolog
- hypoxia-inducible factor-proline dioxygenase
- Synaptosomal-associated protein
- Protein Mo25
Sequence:
MLPYQAAVAMDYAGYQRQPTPGHPGSHMATMGSLGMPAVPFTHSWMVPTQDLCAMPPYNKMTGHQQPPGAGMHAQQQPLEPGILELRKEKSRDAARSRRGKENYEFYELAKMLPLPAAITSQLDKASIIRLTISYLKLRDFSGHGDPPWTREASSSSKLKSAAIRRSPAVDLFEQHQGTHILQSLDGFALAVAADGRFLYISETVSIYLGLSQVEMTGSSIFDYIHQADHSEIADQLGLSLTSGGGGGGGSSSSGGGGGGAGGGMASPTSGASDDGSGTHGTNNPDVAASMTQASTSGYKGYDRSFCVRMKSTLTKRGCHFKSSGYRASDATSNCNNGNNASNNAKNVKNPGSNYSVVLLLCKLRPQYTFSHSRKSQPPLLGMVALAIALPPPSVHEIRLECDMFVTRVNFDLRVAHCEPRVSDLLDYSPEDLVNKSLYSLCHAEDANRLRKSHSDLIEKGQVLTGYYRLMNKSGGYTWLQTCATVVCSTKNADEQNIICVNYVISNRENENMILDCCQLEPSPDSIKHEEGLGNDKSSGSPGGDASGEGNSHLSAGDMKLNSPKTDSEGHSHRGRGRSAAASHGSSMNSLTMIKDSPTPLGVEIDSGVLPTTVATPVPAATPPVQSTKRKRKTKASQHAEDQGQEQVISEQPLPKLPTMEQRDQQPRSRLPSIVDEQPSSAADSAVKDLEQAMSKHLPSPAAVVSVAPPNTDFSADSLLKQQQQQQQLDPNEKSSTIQWIGTPYQQPPAPMPATALLRQLYANRESVIRATARQTPTGVGPGVFYGDQQTGPLPTPPGSESSYENQYLQLHSAASGGHPGGQKTSADAFTNLVSTYGGYHSSIDYHNAMTPPSSVSPRDSNQPGKAAPVLASNGGYDYAPDPLRGQYATSSGDVVPATLPLKPQASYTATMHPSGSTTTEGGVTYSNLDQPQYFAPHSSFHLYHKGSPASGWYSTPSXVVDDQGQVPPSCQDQYHHHHHHHHHQDGSAGSSASQASERWDFVGALGKVARMFFSARKGNPG
Protein: Protein dispatched homolog 2 (A7MBM2)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Sonic hedgehog protein
- Desert hedgehog protein
- Indian hedgehog protein
Sequence:
MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAEWPVAVLMLCLAVIFLCTLAGLLGARLPDFSKPLLGFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPDLELNSSSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLWNLHAIHSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQADAARTLALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSAIYQLLHFLLDRDFLSPQTTDYQVPSLKYSLLFLPTPKGASLMDIYLDRLATPWGLADNYTSVTGMDLGLKQELLRHFLVQDTVYPLLALVAIFFGMALYLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALLLLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTTSAAFYASYLSRLPAVRCLALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRWEGSAPRRLLLALHRRLRGLRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYIAGVSPRLRLPTLPPPGGQVFRPSHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLPVDTGDPLDPRSNSSLVRDPAFSASGPEAQRWLLALCHRARNQSFFDTLQEGWPTLCFVETLQRWMESPSCARLGPDLCCGHSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHGSLAALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSLSTEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEALFLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPATVLLYRKLGIILMMVKCVSCGFASFFFQSLCCFFGPEKNCGQILWPCAHLPWDAGTGDPGGEKAGRPRPGSVGGMPGSCSEQYELQPLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHDGPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQDSQGEEAEPLPASPEAPAHSPKAKAADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDLDDTGQPVLERGQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNSQPDLPDVWLRRPSTHTSGYSS
Protein: Putative recombination initiation defects 3 (AtPRD3) (Q0WWX5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.
Subcellular location: Nucleus {ECO:0000255}.
Interaction partners:
- Protein PUTATIVE RECOMBINATION INITIATION DEFECT 1
- Type 2 DNA topoisomerase 6 subunit B-like
- Protein MULTIPOLAR SPINDLE 1
- Meiosis-specific protein ASY3
- Protein DOUBLE-STRAND BREAK FORMATION
- Meiotic recombination protein SPO11-2
- Synaptonemal complex protein 1
- Meiotic recombination protein SPO11-1
- Synaptonemal complex protein 2
- Meiosis-specific protein ASY1
Sequence:
MKMNINKACDLKSISVFPPNLRRSAEPQASQQLRSQQSQQSFSQGPSSSQRGCGGFSQMTQSSIDELLINDQRFSSQERDLSLKKVSSCLPPINHKREDSQLVASRSSSGLSRRWSSASIGESKSQISEELEQRFGMMETSLSRFGMMLDSIQSDIMQANRGTKEVFLETERIQQKLTLQDTSLQQLRKEQADSKASLDGGVKFILEEFSKDPNQEKLQKILQMLTTIPEQVETALQKIQREICHTFTREIQVLASLRTPEPRVRVPTAPQVKAKENLPEQRGQAAKVLTSLKMPEPRVQVPAAPQAKENFPEQRGPVAKSNSFCNTTLKTKQPQFPRNPNDASARAVKPYLSPKIQVGCWKTVKPEKSNFKKRATRKPVKSESTRTQFEQCSVVIDSDEEDIDGGFSCLINENTRGTNFEWDAEKETERILRTARRTKRKFGNPIIIN
Protein: NADPH oxidase 1 (NOX-1) (EC 1.6.3.-) (Q8CIZ9)
Organism: Mus musculus (Mouse)
Function: Pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism.
Subcellular location: Cell projection, invadopodium membrane {ECO:0000250|UniProtKB:Q9Y5S8}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q9Y5S8}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cytochrome b-245 light chain
- NADPH oxidase organizer 1
- Neutrophil cytosol factor 2
- Neutrophil cytosol factor 1
- NADPH oxidase 4
- Neutrophil cytosol factor 4
- NADPH oxidase 2
- NADPH oxidase activator 1
- NADPH oxidase 3
- NAD
Sequence:
MAGELRGSRGPLQRIQIAPREAPNLHLTMGNWLVNHWLSVLFLVSWLGLNIFLFVYAFLNYEKSDKYYYTREILGTALALARASALCLNFNSMMILIPVCRNLLSFLRGTCSFCNRTLRKPLDHNLTFHKLVAYMICIFTVIHIIAHLFNFERYRRSQQAMDGSLASVLSSLSHPEKEDSWLNPIQSPNMTVMYAAFTSIAGLTGVIATVALVLMVTSAMEFIRRNYFELFWYTHHLFIVYIICLGIHGLGGIVRGQTEESLGESHPHNCSHSFHEWDDHKGSCRHPHFAGHPPESWKWILAPIAFYIFERILRFYRSQQKVVITKVVMHPSNVLELQMRKRGFSMEVGQYIFVNCPSISFLEWHPFTLTSAPEEEFFSVHIRAAGDWTRNLIRTFEQQHSPMPRIEVDGPFGTVSEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQRADNKLKTQKIYFYWICRETGAFAWFNNLLNSLEQEMEELGKMDFLNYRLFLTGWDSNIAGHAALNFDRATDILTGLKQKTSFGRPMWDNEFSRIATAHPKSAVGVFLCGPRTLAKSLRKRCQRYSSLDPRKVQFYFNKETF
Protein: Protein ZDS1 (Protein NRC1) (RT2GS1) (P50111)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has a role in establishing cell polarity. Together with cAMP-dependent protein kinase regulatory subunit BCY1, provides a negative feedback control on the cell wall integrity-signaling pathway by acting as a negative regulator of MAP kinase SLT2/MPK1. In heat-stressed cells appears to play a role in localizing BCY1 to the cytoplasm. Seems to interact with, and down-regulate, CDC42. Also acts as a suppressor of PKC1. May act as an integration point for distinct signaling pathways helping to maintain a balance among these different pathways.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:8816439}. Note=Concentrated at incipient bud site of unbudded cells and at the bud tip of small and medium-sized buds.
Interaction partners:
- Protein phosphatase PP2A regulatory subunit B
- Serine/threonine-protein phosphatase PP2A-2 catalytic subunit
- Protein ZDS2
- Protein phosphatase PP2A regulatory subunit A
- Mitosis inhibitor protein kinase SWE1
- Cyclin-dependent kinase 1
- Serine/threonine-protein phosphatase PP2A-1 catalytic subunit
- SIR4-interacting protein SIF2
- Separin
- M-phase inducer phosphatase
Sequence:
MSNRDNESMLRTTSSDKAIASQRDKRKSEVLIAAQSLDNEIRSVKNLKRLSIGSMDLLIDPELDIKFGGESSGRRSWSGTTSSSASMPSDTTTVNNTRYSDPTPLENLHGRGNSGIESSNKTKQGNYLGIKKGVHSPSRKLNANVLKKNLLWVPANQHPNVKPDNFLELVQDTLQNIQLSDNGEDNDGNSNENNDIEDNGEDKESQSYENKENNTINLNRGLSRHGNASLIRRPSTLRRSYTEFDDNEDDDNKGDSASETVNKVEERISKIKERPVSLRDITEELTKISNSAGLTDNDAITLARTLSMAGSYSDKKDQPQPEGHYDEGDIGFSTSQANTLDDGEFASNMPINNTMTWPERSSLRRSRFNTYRIRSQEQEKEVEQSVDEMKNDDEERLKLTKNTIKVEIDPHKSPFRQQDEDSENMSSPGSIGDFQDIYNHYRQSSGEWEQEMGIEKEAEEVPVKVRNDTVEQDLELREGTTDMVKPSATDDNKETKRHRRRNGWTWLNNKMSREDDNEENQGDDENEENVDSQRMELDNSKKHYISLFNGGEKTEVSNKEEMNNSSTSTATSQTRQKIEKTFANLFRRKPHHKHDASSSPSSSPSSSPSIPNNDAVHVRVRKSKKLGNKSGREPVEPIVLRNRPRPHRHHHSRHGSQKISVKTLKDSQPQQQIPLQPQLEGAIEIEKKEESDSESLPQLQPAVSVSSTKSNSRDREEEEAKKKNKKRSNTTEISNQQHSKHVQKENTDEQKAQLQAPAQEQVQTSVPVQASAPVQNSAPVQTSAPVEASAQTQAPAAPPLKHTSILPPRKLTFADVKKPDKPNSPVQFTDSAFGFPLPLLTVSTVIMFDHRLPINVERAIYRLSHLKLSNSKRGLREQVLLSNFMYAYLNLVNHTLYMEQVAHDKEQQQQQQQQP
Protein: Galectin (J3QSH0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAFSGCQAPYLSPAVPFSGTIQGGLQDGFQITVNGAVLSCSGTRFAVDFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQKGTWGPEERKMHMPFQKGMPFDLCFLVQSSDFKVMVNGSLFVQYFHRVPFHRVDTISVNGSVQLSYISFQPMPFITTIPGGLYPSKSIILSGTVLPS
Protein: Transmembrane 9 superfamily member 12 (Endomembrane protein 7) (Transmembrane nine protein 12) (AtTMN12) (F4JRE0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endosome membrane {ECO:0000250|UniProtKB:P32802}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q940G0}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein CANDIDATE G-PROTEIN COUPLED RECEPTOR 7
- Lung seven transmembrane receptor family protein
- RING-type E3 ubiquitin transferase
- 3-oxo-5-alpha-steroid 4-dehydrogenase
- Rhomboid-like protein 15
- Protein RETICULATA-RELATED 2
- Pentatricopeptide repeat-containing protein At1g06140
- Probable inactive purple acid phosphatase 2
- Probable protein S-acyltransferase 13
Sequence:
MFGVYRVFVLLVFVSQLCNGFYLPGSYMHTYSDGDSIFAKVNSLTSIETELPFSYYSLPYCQPLEGIKKSAENLGELLMGDQIDNSAYRFRMRTNESLYLCTTSPLNEHEVKLLKQRTRELYQVNMILDNLPALRFAKQNGVTIQWTGYPVGYSPPNSNDDYIINHLKFKVLVHEYEGNVMEVIGTGEEGMGVISEADKKKALGYEIVGFEVVPCSVKYDAEKMTKLHMYDPVPSVNCPLELDKAQIIKEHERITFTYEVEFVKSETRWPSRWDAYLKMEGARVHWFSILNSLMVIFFLAGIVFVIFLRTVRRDLTKYEELDKEAQAQMNEELSGWKLVVGDVFREPEMSKLLCIMVGDGVRITGMAVVTIVFAALGFMSPASRGMLLTGMIILYLFLGIVAGYAGVRLWRTVKGTSEGWRSLSWSIACFFPGIAFVILTVLNFLLWSSNSTGAIPISLYFELLALWFCISVPLTLFGGFLGTRAEAIQFPVRTNQIPREIPERKYPSWLLVLGAGTLPFGTLFIELFFIFSSIWLGRFYYVFGFLLIVLLLLVVVCAEVSVVLTYMHLCVEDWRWWWKAFYASGSVALYVFAYSINYLVFDLQSLSGPVSAMLYIGYSLLMAIAIMLATGTIGFLTSFYFVHYLFSSVKID
Protein: Large ribosomal subunit protein uL3m (39S ribosomal protein L3, mitochondrial) (Q9VXQ0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL17m
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein bS16m
- Mitochondrial ribosomal protein L2
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein bL20m
- Ribosomal protein
- Large ribosomal subunit protein bL9m
Sequence:
MMRSVINQLLGLRLSGNSSVLVTQVRDKGHLSRPRLRNPQWFLRKEITKYNDLMTAENKQFVNEVGTNNFGVPAVIKDSLVKTAGPTANEAVWTPNLRRCGVIARKIGQYPLWLKNGERIRTTLLQIVDNHVIKYIPPEEYLPAQVPTVANLHKRGCILVGSETTNPALLTKEYAGIFRNSGVLPKKNLARFIVSPEAQLAPGTPLNVNHFRVGDFVDVRGKTVDHGFQGVVKRHGFKGMPASHGVTKTHRRAGNIGGGGEKGRVWPGTKMPGHMGNRWRIIKGLRVWRINTKYNVMWVQGSSVAGPTGGLVYIYDTILPTRKNKEAPPFPTFYGEPQQDGDDVWYEQVHNFKSESITYENE
Protein: Small ribosomal subunit protein uS14m (37S ribosomal protein MRP2, mitochondrial) (P10663)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Small ribosomal subunit protein uS19m
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS15m
- Large ribosomal subunit protein bL27m
- Small ribosomal subunit protein uS12m
- Large ribosomal subunit protein bL36m
- Small ribosomal subunit protein uS17m
- Small ribosomal subunit protein mS35
Sequence:
MGNFRFPIKTKLPPGFINARILRDNFKRQQFKENEILVKSLKFIARNMNLPTKLRLEAQLKLNALPNYMRSTQIKNRCVDSGHARFVLSDFRLCRYQFRENALKGNLPGVKKGIW
Protein: Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen) (Q02413)
Organism: Homo sapiens (Human)
Function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q7TSF1}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q7TSF1}. Cell junction, desmosome {ECO:0000269|PubMed:34368962}. Cytoplasm {ECO:0000269|PubMed:34368962}. Nucleus {ECO:0000269|PubMed:34368962}.
Interaction partners:
- Desmocollin-1
- Desmoplakin
- Corneodesmosin
- Plakophilin-1
- Junction plakoglobin
- Plakophilin-2
- Filaggrin
- Plakophilin-3
- Desmocollin-3
- Periplakin
Sequence:
MDWSFFRVVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGLSSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRITKYSTVQYSK
Protein: V-type ATPase assembly factor PKR1 (A0A1D8PSF9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein E
- Sm protein B
- Sm protein F
- DUF866-domain-containing protein
- Small nuclear ribonucleoprotein Sm D3
- Increased recombination centers protein 6
- U1 small nuclear ribonucleoprotein C
- U5 snRNP GTPase
Sequence:
MSFFVELWESVFTPGTTPALITATHASFILLIISLLVLIFLTKSIHFINLLVIAVLLYASVFWFINELQQVKLQSNNELSQKELEKESESEKLSANATESSQTTATSEDIKLRKRKV
Protein: Protein bangles and beads (P29746)
Organism: Drosophila melanogaster (Fruit fly)
Function: May play an important role during development.
Interaction partners:
- Isochorismatase domain-containing protein 1
- GH12014p
Sequence:
MKCQLLFVATVCLASVWALPVPDEEVAIQPDSGAKAELLTKTVLPTAVEPAPLKPEAEKPAETKTIEAKAAVPEQPDVNANPSPSTPAAEPAKEINSVELKSSAPDVETAPAIPEKKTLPEEAKPAQENAPVEAEKKQEKTARTEAEPTVEAQPQATKAIEQAPEAPAANAEVQKQVVDEVKPQEPKIDAKSAEEPAIPAVVAAEKETPVPEQPARQERINEIEQKDAKKDAAVAEEPAKAAEATPTAAPEAATKSDSNIQVIAPEKKSIESSPAAAAASPAAQAAQAKSGEAPKPVDQQKSTETVAESAPVLKTNAPLAPAGATKVTEAVKEQEKEQPAADTAAKALPEQKKTEETAAPAGAPEPTAAVAPAAVPEAKKIDEAPAAETVVKGEEAIAKPIAQSPSAEPKKSSEEKSDKSESKVDESSESKESEESSESKEN