wanglab/gogpt-training-data huggingface dataset:
Protein: Quinoprotein amine dehydrogenase, beta chain-like RIC1-like guanyl-nucleotide exchange factor (F4JEA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MAYGWPQVIPLLPGSQRVVYLKLAGRLLLVVSPSHLELWGSSQQRVRLGKYMRDDKSLREEGENLQAVWSPDSKLIAVLVPFAGKDLSVSNFVRDSKTMLLGLSDGSLYSISWKGEFGGAFSIGSHPSASNDDRLLSYTLGNGLVSGVASPTLASDDKFSTKPAIVQLELCTRSKLLFVLNSDGQLVVCSVNKKGLKYTESIRAEKKLGGDAVCASVASEQQILAVGTRKGMVELYDLSHSISLLRTVSLHDWGYSADYTGPVNNIAWTPDNSAFAVGWKSRGLAVWSVSGCRLMSTVRQIGLTSTSSPKINPKQDCKYEPLMSGTSAIQWDEYGYRLFATEEASCDRILAFSFGKCCLNRGVSGKTYVRQVMYGDDRLLMVQAEDTDELKLLHLKLPVSYISQNWPVQHVAASEDGKYLAVAGLHGLILYDVRFKKWRVFGDVSQEQQIHCKGLLWLGKIVVICNFIEASETYELLFYPRYHLDQSSLLCRKVLLGKPMVMDVYQDYILVSYLPFIIHVYHVKIYGELTPSSKADLQLSTVRELSIMTAKSHPAAMRFVPDQHPREGELDEDNLSSDLSEREPSRCLILRGNGELSLLDLVDGRERELTDSVELFWVTCGQSEEKTNLVEEVSWLDYGHRGMQVWYPSLGDDPFMQEDFLQLDPELEFDREVYPLGLLPNVGVVVGVSQRMSFSASAEFPCFEPTPQAQTILHCLLRHLLQRDKNEEALLLAQLSAEKPHFSHCLEWLLFTVFDAEISRPNPNRNQISGPGHLKKLSLLRKACDLIKNFPEYYDVVVNVARKTDARHWADLFSAAGISTTLFEDCFQRRWYRTAACYILVIAKLEGVAVSQYCALRLLQATLDESLYDLAGELVRFLLRSGRDIEQAPTESDSLSPKLLGFLIFGSSHKKSSLDKSSSFKEQSPHVASVKSILESHASYLMSGKELSKLVAFVKGTQFDIVDFLQRERYGCAQLQNFAAGLELIGQKLQMSELQNRLDAEFLLAQMCSVKFKEWIVVLATLLQRSEVLYDIFRYDLRLWKAYSVTLESHLAFAQYHDLLQILEAKLSATSREESNRGSIS
Protein: Keratin 13 (K7EQH6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEMQIESLNEELAYMKKNHEEEMKEFSNQVV
Protein: Probable cystathionine gamma-synthase (EC 2.5.1.48) (O-succinylhomoserine (thiol)-lyase) (O74314)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10759889}. Nucleus {ECO:0000269|PubMed:10759889}.
Interaction partners:
- Cystathionine beta-lyase
- Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- Cysteine synthase 1
- Homoserine O-acetyltransferase
- Sulfite reductase subunit beta
- Cysteine synthase 2
- Homocysteine synthase
- Adenosylhomocysteinase
- Probable sulfite reductase flavoprotein component
- Homoserine dehydrogenase
Sequence:
MSANISYLVNPPTEVGSSIPADTEHAISVTLPTWKSNVGYEEGDPNVTTKMKSGYPRFFISAHVKDCISIIKKFPEIEILKLKDYDMFLYPSLSVAKQSAAFLESKGPIDSAEVIIYDATKGLRKHLDSIDRNRKYTEEIHIPQVYSVLFPSKYFGIAKQFWQHTGDGISSRRAAAFLHSYKKIQSISEFLVAQRSISHLKSKSRSRYASHPDLQALNTWMTNEGNQANDEMEDVSLYLEERYGRNLDLSLATAAKLVLRRRIAGTLKDEVDLQKALPKEGSQYLREVKGLSHDDVFLFPTGMSAIYNTHRILRLVLDDSRKSVCFGFCYVDTLKILQKWGSGCYFYGLGNDEQLDEFEKRLESGEKVMALFCEFPSNPLLNSPDLVRIRKLADSYDFAVVVDETIGNFVNVEVLPLADVVVSSLTKIFSGDSNVMGGSMVLNPSSRYYSRIKDAMKALYEDLLYDEDALTLERNSRDFAERSQVINHNAETICNLLYQNPKIKTLYYPKYNTSKEHFEACRRENGGYGGLLSVVFHNPEDARQFYDKIQVAKGPSLGTNFTLASPYAILAHYQELDWAGENGIDRNLVRVSVGMEPSEHLKNVFINALS
Protein: DNA ligase-like protein (F4IFY5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- AT5g59210/mnc17_100
- Guanylate-binding family protein
- AT5g42220/K5J14_2
- Meiosis-specific protein ASY3
- Clustered mitochondria protein
- Putative recombination initiation defects 3
- DNA topoisomerase 2
- DNA polymerase alpha catalytic subunit
- DNA replication licensing factor MCM5
- DNA replication licensing factor MCM2
Sequence:
MSSTRRGTKRTRPEPPQSLKKPTPKAKLPDELDVDVSSDFKGIMSALQQFREKAHEDGRKKKEESISSVSTEVKSKIDELKSKLEKERQNFSKALSKSSKECENILKDEAAKFEELHKKFVKDKADHLQGLKDTISKFEEDKERLYMRYEQLRKKEKTMITEQEKFCTEKLAQLEESLKKKKRGDKTFSILRKTLGSFLENEASDEEFPPDE
Protein: Ribosomal RNA-processing protein 43 (Q6DRN4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MAAGFKTAEPLEYHRSFLKENCRPDGRELGEFRPTTLNINSISTADGSALVKIGNTTVICGIKAELAVPPSEAQNKGYLVPNVDLPPLCSSRFRAGPPGEQAQAASQFIADVIESSDLINLEELCIEKAKLCWVLYCDIMCLDYDGNLLDACITVLLAALKTAQLPEVTINKETDLAEVDIEKKRRLKINRHPVGSSFAVFDDSIIIVDPTAEEESLSTALMTVVTDEEDRLCAVHKPGGTSLSGEKLQHCINRALTRNKEIRKLLDKVHESTKTMK
Protein: BZIP domain-containing protein (H2L0F6)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MQQNIQYTYSSDPRSGGNQNQQLHGISQFQQNSYQPTTYSNSNANNFHSSNSATFIPNSVTQTPQRRMGEEKSLVNMLDAYFIDSTTPSTSTSWNNQQPVQMSSIQQSVGSYNQQIPQLKVGDVDLQVEGMNVKLSSSPDKGEKDRVKKARQAEAARMRYHRLSNEEKRELNLKRTLAQKRKRQREKEMEELESILRETNDIQEDPDITEQLREKRMRAKWAEAARTRYARMTPEERRAHNTRRRMRQMQNAMSAIKACGMATGDPQKDDEAVRLHIKTQNAKKAEAARQRYHRMNDDEKRVYNQRRTEAFRRRRMEEEMLLAMPIGRINGEALDRAQQIVVRNAKRAEAARLRYQRMTPDQRKVAKQEPKEESWPSHEQSDTQIDHDLDLGDSYNQKRYTPKRRRNEMDDMISAGQMAVGSSGTITMGTGTPAKKDDMDALSSLERDVVKRTQHAQQILLRQRANQSSGTPRSVTPPPQAYIISNGQQQHQQLVGNQGNNGIGQHQVLHQGHMQQQQIQVSHQQSSQSIPQNIYTSGMIIQNQGQQQQGQQQQQGQSQQILNNPYRT
Protein: TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit) (Q28GG8)
Organism: Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Function: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis (By similarity). Binds to the promoters of select genes.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P20226}.
Interaction partners:
- Transcription initiation factor TFIID subunit 8
- TATA-box binding protein associated factor 2.
- Sorting and assembly machinery component 50 homolog.
- TAF7 RNA polymerase II, TATA box binding protein
- Transcription initiation factor TFIID subunit.
- TATA box-binding protein-like 1
- Arginyl-tRNA synthetase 2
- Neuronal PAS domain protein 3.
- TATA-box binding protein associated factor 6.
- B-TFIID TATA-box binding protein associated factor 1.
Sequence:
MDQNNSIPPFQGLASPQGSLTPGINIFSPLMPYGTGLTPQPVQTTNSLSILEEQQRQQQQAQQSTSQQGNQGSGQTPQLFHPQTLTTAPLPGNTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
Protein: Bacterioferritin-associated ferredoxin (Bfd) (P0AE56)
Organism: Escherichia coli (strain K12)
Function: Seems to associate with BFR; could be a general redox and/or regulatory component participating in the iron storage mobilization functions of BFR. Could participate in the release or the delivery of iron from/to bacterioferritin (or other iron complexes).
Interaction partners:
- Bacterioferritin
- Bacterial non-heme ferritin
- Ferric siderophore reductase
Sequence:
MYVCLCNGISDKKIRQAVRQFSPHSFQQLKKFIPVGNQCGKCVRAAREVMEDELMQLPEFKESA
Protein: Protein-arginine deiminase (EC 3.5.3.15) (O57400)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|PIRNR:PIRNR001247}.
Interaction partners:
Sequence:
MAQQRRVQLCTQRPTSTVCVLGTELSLDIQGSAPKDAIAFHVQGTPGVKVYVVHETQSVKLPSSVTRWPLATGTEVLLTMEAISKDVGDEKVRISYFGEASGVPVGRAMLYLTCVDISLDADTGRNGSVSKTLVDKATWTWGPDGHGAILLVNCDRDDPKSRLMGDSSEPQSQLTDNRDTVVCSYEDLKDMSQMVLRTRGPRTIFTGHGLVLHVNFSDADKVGVFYGGNSIALEEYKHVLGGEKLAYAVKPSQHQEESIFYVEGLAFPDVSFSGLVAFHVTLLESPEKGLLETPIFTDTVVFRMAPWIMTPNTLAPLEVFVCSVKDNEDFVAAVSALAEEAKCPVTICPLPENRNDRWIQDEVEFGYVQAPHKMFPVVLDSPRDRGLKDFPVRSILGPDFGYVAQETPENTSSLDSFGNLEVSPPVTVRSKEYPLGRILIGSSFPRFGGRRMAKAVRNFLAAQRVQAPVELFSDWLQVGHVDEFLSFIPAPDRKGFRLLLASPSACYQLLREKQEMGYGEATMFQGLHGVPKPSISEILGNEALRKFNAYAQSCISWNRDILKRELGLAEQDIIDIPQLFQADHQARAVAYFPDMVNMLVLGRHLGIPKPFGPLVDGQCCLEERVRALLQPLGLSCTFINDYFSYHKLAGEVHCGTNVRRKPFAFKWWRMVP
Protein: CRIB domain-containing protein (Q8MQE6)
Organism: Caenorhabditis elegans
Interaction partners:
- Actin-related protein 2
- Cell division control protein 42 homolog
- Probable actin-related protein 2/3 complex subunit 3
- Probable actin-related protein 2/3 complex subunit 2
- Actin-related protein 3
- WH2 domain-containing protein
- Probable actin-related protein 2/3 complex subunit 4
- Actin-related protein 2/3 complex subunit
- Actin
- Transducer of Cdc42-dependent actin assembly protein 1 homolog
Sequence:
MWMVVSEDPAGRLRYQYHNLPVAQSFPPPSHPPPPSATTNPSSNKPSTVSSAAQIYSSFPSSTSSSGTGGHLHHNHMQRFARGGCSSFPDSMGSSPRTTHRSHTLPNGGYYEMEQYDNVNDYSTYGGPDSTSSSTSSSAEYQDPVYSTRYGGSTGTYARRQNYARCYVPISADAFYYYHNQQKQLQQQHHQQQQQQLAFRPRHRSSHHHQEPRRHRAPSPDPDYSPPLSRNKVRFHIPEEPVSRGDYVSSRHVFNTDDFGDEDDDYESVSMNPDPAPHSDSVLVHRSNGQVSVMVTKKEEPIYCSGGSDSSTESSSATPSSVEADTPPPIPSHPPARHRLVKKSSSSTSISLNGIGSTPTRQFEITQAYGGTIRGPPMAIGGGQGITQMGTMAAAPQSHTHTDGNASSSGSWFRKDKNKKKDKKSKIKKEDISNPTNFQHKAHVGWNQDSGFSNTVYDDDMDEATKNILKAAGLESNNLNEDDKKFVKKFIAKNYDKYVSVGSLDPSQISSPLPPPIQQHPQMNQSWNQTPVRQYKPSFPSSAPIGSGASSYSTPAAPPPPTRVESHGLAPARPPPPPPSSGTRGIAPSRPLPQAPNYGTPENRPHAVPPPPPPPPPQSFGMAPISSAAPPPPPPPPPMGLPAVGAGAPPPPPPPPPSGAGGPASVLAKLPPAQDGRSNLLAEIQAGKQLRSVQQTADSPKSAGGDARGDVMAQIRQGAQLKHVDAAAEQERRKSTTSGAAGMGGLAGALAKALEERRMNMGIDDTSDDDDDEDDKNEWSD
Protein: Klaroid protein (A0A0B4KEE4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton (By similarity). Is required to nuclear migration in eye and to anchor klar in the nuclear membrane.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000269|PubMed:32066907}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:18820457, ECO:0000269|PubMed:32066907}. Note=Lam is required for perinuclear localization of Koi (PubMed:18820457). In the fat body, localizes to a perinuclear non-centrosomal microtubule-organizing centers (ncMTOCs) (PubMed:32066907). {ECO:0000269|PubMed:18820457, ECO:0000269|PubMed:32066907}.
Interaction partners:
- Muscle-specific protein 300 kDa, isoform G
Sequence:
MSENTYQIETRRRSRSKTPFLRSSCDHENCEHAGEEGHVHHLKRKSAAPNVQTIIEEHIVESSISKKTRAKAFAQLTSDYSSDDMTPDAKRKQNSITATVTSILTKRSGGATSTPRNRSQLETTQNTLNSAQEKLNQSNGNLSSGNVSDYLAYIEYRDAGEYWNKTPKTDYTYSELSPHRRQLAPGIVAMPNMSRKSLENHNDRVNYMVQQNPAQEEFIRRRYQSKYTQQVNYDSADELDATFGQQKQSWWLIRLIQLVVSSITTVWSRVTNLSATETTAYQNYHAKRQQSQQVGLWWKIVQTIGGGLASLLRYLYVFIGSVLSLDTWLLRSSDAENKSKKRFLIFLLILLPLLLLSGWLLLQEDQRSAYVQRAEALLPLPLSIFGSLRSRFSNAGATLKSWMEVPTVRSPQREAEAIKVNMASIEQNIQKALTAEEYENILNHVNSYVQQLVELKMQQHSKELAPQQIELFVKLMKENLKQIMYKTELSEKDLSDLAIKLKLELQSSGGWQDGAKLSQANLEEITKLIKAEVHLHESHYTIQLDRIDFASLLERILAAPALADFVDARISLRVGELEPKESSGSSDAEVQIERLNREIAFIKLALSDKQAENADLHQSISNLKLGQEDLLERIQQHELSQDRRFHGLLAEIENKLSALNDSQFALLNKQIKLSLVEILGFKQSTAGGSAGQLDDFDLQTWVRSMFVAKDYLEQQLLELNKRTNNNIRDEIERSSILLMSDISQRLKREILLVVEAKHNESTKALKGHIREEEVRQIVKTVLAIYDADKTGLVDFALESAGGQILSTRCTESYQTKSAQISVFGIPLWYPTNTPRVAISPNVQPGECWAFQGFPGFLVLKLNSLVYVTGFTLEHIPKSLSPTGRIESAPRNFTVWGLEQEKDQEPVLFGDYQFEDNGASLQYFAVQNLDIKRPYEIVELRIETNHGHPTYTCLYRFRVHGKPPAT
Protein: Carboxypeptidase Q (E5RJP8)
Organism: Homo sapiens (Human)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MKFLIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQNRSYERLALLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLEKVHLEPVRIPHWERGEESAVMLEPRIHKIAILGLGS
Protein: Bcl-2-like protein 15 (Bcl2-L-15) (Bcl-2 family kin) (Bfk) (Q08ED0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MSKMKNPRTFEEQTECIVNSLLKDFRTPLSHAANRNLSGADEPCSGEDYSFDVAIIVGRLRILGDQFNGELEASANNIIAVTIGGQAGSTVLNDTVQSLSRTWCTQDPTLVFERAFLAVSVKLLEYVVRKAPNVARQVANYVTGMINGNTAIREFIQGQGGWENLES
Protein: Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (A4D1U5)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004637}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004637}. Mitochondrion intermembrane space {ECO:0000256|ARBA:ARBA00004569}.
Interaction partners:
Sequence:
MTVFFKTLRNHWKKTTAGLCLLTWGGHWLYGKHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACKGKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGETSSLSHTLFAESGNKVQHITDATLAIVKGETVPLDVLQIKGEKEQPVFAMTGLRWGSFRDAGVKVSKYWYLGPLKIKAAHFFSTLKEWPQTHQASISYTGPTERPPNEPEETPVQRPSLYRRILRRLASYWAQPQDALSQEVSPEVWKDVQLSTIELSITTRNNQLDPTSKEDFLNICIEPDTISKGDFITIGSRKVRNPKLHVEGTECLQASQCTLLIPEGAGGSFSIDSEEYEAMPVEVKLLPRKLQFFCDPRKREQMLTSPTQ
Protein: AAA-ATPase At3g28610 (EC 3.6.1.-) (Q9LJJ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MMGNMFGSSLASLFFLWATIQQIFPNHLKIAIKEFFLSTIQQISFAKRFSDKFINFFSPYVQINFSEYEDYRVNHAFDPIETYLGAKATDKAKHLRASQVRESKGLVLKRDETKVRDEYEGIRVWWEMETDSAGYKTLKLTFHRRSRDIVTNSYIKYVVEEGKSIDAKNKKMKLFTNNPSSHWGSSKTSFWRYIDFEHPATFETLAMDPKKKEQILNDLAAFNNGKDYYKKIGKAWKRGYLLYGPPGTGKSTMIAAMANLLNYSIYDLELTAIQNNSELRKILTATSNKSIIVIEDIDCSLDLTGKRKKKESNLMIWRKDGDQDNEENKSFVTLSGLLNFIDGIWSACGQERIIVFTTNHLAKLDPALIRRGRMDMHIELSYCTFEAFKTLAKNYLDLDSHPLFSKIESLMKETNIAPADVAENLMKKNRETDADGSLNDLIESLERKKKVQIAQVDEHKEYSNKIVEAFRKLF
Protein: Alpha-mannosidase (P96937)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible sugar kinase
- Possible malonyl CoA-acyl carrier protein transacylase FabD2
- Uncharacterized protein
- Galactokinase
- Uncharacterized transporter Rv1999c
- MobA-like NTP transferase domain-containing protein
Sequence:
MMGGTYNEPNTNLTSPETTIRNLVHGIGFQRDVLGAEPATAWQLDVFGHDPQFPGLAADAGLTSSSWARGPHHQWGPAQGGVDRMQFCSEFEWIAPSGRGLLTHYMPAHYSAGWSMDSSTSLADAEAATYALFDQLKKVALTRNVLLPVGTDYTPPNKWVTAIHRDWGARYTWPRFVCALPKEFFAAVRAELAKRGWVPSPQTRDMNPIYTGKDVSYIDTKQANRAAENAVLEAERFAVFAALLTGAEYPQAALAKAWVQLAYGAHHDAITGSESDQVYLDLLTGWRDAWELGRAARDNSLRLLSGAVAASHDRVVVWNPLTQRRTDIVTARVDPPLQAGVRVFDPDGAEVAALVEHDGRSVTWLACDVPSLGWRVYRLVPADEAPGWELVPGTDIANEHYRLAVDPERGGALSSLVQDGRQLIAAGRVANELALYEEYPSHPTQGEGPWHLLPTGPVVCSSACPAQVQAYRGPLGQRLVVRGRIGTLLRYTQTLTLWDGVDRVDCRTSIDEFTGEDRLLRLRWPCPVPGAMPISEVGDAVVGRGFALLHEGPESVDTAQHPWTLDNPAYGWFGLSSAVRVRAGDGVRAVSVAEVVSPTETVSGPMARDLMVALVRAGVTATCSGADKPRYGHLDVDSNLPDARIALGGPDRNTFTKAVLAEAAPAYTAELQRQLAKTGTARVWVPAANPLARAWLPGADLRAPCALPVLVIDGRDEKHLRAAVASLADDLADAEIVVHQRAAPQMEPFEDRTVALLNRGVPSFAVDSEGTLHTALMRSCTGWPSGVWIDQPRRTAPDGSNFQLQHWTHHFDYALVCGGGDWRRAGIPARSAQFSHPLLAVAPRRPQGELPAVGSLLHVEPADSVQLGALKAAGNPLAAGSARPVQPAAVALRLVQTTGADTPVTIGCELGKVGALRPADLLETPLAMARARKSSIDLHGYQVATVLARLDVAADMANVLAADDVALAPHAETAQPQYARYWLHNRGPAPLGGLPAVAHLHPRRVRGQPGDDVVLRLTAASDCTDSVLGGVVDVVCPLGWPATPARLPFTLGAGAHLQADIALSIPAGAPPGPYPVRAQLRVVDTAVPAAWRQVVEDVCVVTVGADSDLEELVYLVDGPADIELAAGDRARLAVTIGSRAHAELALDAHSISPWGTWEWIGPPALGAVLPARGMAKLAFDVTPPAWLEPGQWWALVRVGCAGQLVYSPAVKVSVT
Protein: Formate dehydrogenase H (EC 1.17.98.4) (Formate dehydrogenase-H subunit alpha) (FDH-H) (Formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide) (P07658)
Organism: Escherichia coli (strain K12)
Function: Decomposes formic acid to hydrogen and carbon dioxide under anaerobic conditions in the absence of exogenous electron acceptors.
Interaction partners:
- Formate hydrogenlyase subunit 7
- Formate hydrogenlyase subunit 2
- Formate hydrogenlyase subunit 6
- Formate hydrogenlyase subunit 5
- Formate hydrogenlyase subunit 4
- Formate hydrogenlyase subunit 3
- Putative oxidoreductase UacF
- Sulfur carrier protein FdhD
- NADH-quinone oxidoreductase subunit F
- Electron transport protein HydN
Sequence:
MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLKGYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDAIQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNAINEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIALKNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSASEIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRGQNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAHGEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGEHEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHLCPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPIDKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEALVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCAVRVEPIADQRAAEQYVIDEYNKLKTRLREAALA
Protein: Beta-hexosaminidase 2 (EC 3.2.1.52) (Beta-GlcNAcase 2) (Beta-N-acetylhexosaminidase 2) (Beta-hexosaminidase 3) (AtHEX3) (N-acetyl-beta-glucosaminidase 2) (Q9SYK0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Has a broad substrate specificity. Can use synthetic substrates such as p-nitrophenyl-beta-N-acetylglucosaminide, p-nitrophenyl-2-acetamido-2-deoxy-beta-D-glucopyranoside (pNP-GlcNAc), p-nitrophenyl-2-acetamido-2-deoxy-beta-D-galactopyranoside (pNP-GalNAc), 4-methylumbelliferyl-2-acetamido-2-deoxy-beta-D-glucopyranoside (MU-GlcNAc), and 4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-D-glucopyranoside (MU-GlcNAc-6SO(4)) as substrates. Removes terminal GlcNAc residues from alpha1,3- and alpha1,6-mannosyl branches of biantennary N-glycans without any strict branch preference.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17644627}.
Interaction partners:
- Glycoprotein 3-alpha-L-fucosyltransferase A
- Putative fucosyltransferase-like protein
- Beta-hexosaminidase 1
- Beta-hexosaminidase 3
- Alpha-
- Alpha-galactosidase 2
- Alpha-galactosidase 3
- Alpha-galactosidase 1
- Beta-galactosidase 17
- Beta-galactosidase 2
Sequence:
MLTLSKFHVILIPILFFITLLSPLFSIALPINIWPKPRFLSWPQHKAIALSPNFTILAPEHQYLSASVTRYHNLIRSENYSPLISYPVKLMKRYTLRNLVVTVTDFSLPLHHGVDESYKLSIPIGSFSAHLLAHSAWGAMRGLETFSQMIWGTSPDLCLPVGIYIQDSPLFGHRGVLLDTSRNYYGVDDIMRTIKAMSANKLNVFHWHITDSQSFPLVLPSEPSLAAKGSLGPDMVYTPEDVSKIVQYGFEHGVRVLPEIDTPGHTGSWGEAYPEIVTCANMFWWPAGKSWEERLASEPGTGQLNPLSPKTYEVVKNVIQDIVNQFPESFFHGGGDEVIPGCWKTDPAINSFLSSGGTLSQLLEKYINSTLPYIVSQNRTVVYWEDVLLDAQIKADPSVLPKEHTILQTWNNGPENTKRIVAAGYRVIVSSSEFYYLDCGHGGFLGNDSIYDQKESGGGSWCAPFKTWQSIYNYDIADGLLNEEERKLVLGGEVALWSEQADSTVLDSRLWPRASALAESLWSGNRDERGVKRCGEAVDRLNLWRYRMVKRGIGAEPIQPLWCLKNPGMCNTVHGALQDQ
Protein: Neuropeptide Y receptor Y8b (U5KSL6)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
SSRWWKEMTWGDTDECPTSMSGTTFLIVAYSALIGVGLIGNICLVFVITRQKEMRNVTNIFIANLSISDILMCIVCLPVTIIYTLMDRWILGEALCKVTPFVQCISVTVSVFSLVLIAMERHQLIIHPTGWKPVVGHSYLAVAITWMVACFISLPFLSFNVLTNSPFQNISLPFNPFTDHFICMERWPSEHKRLAYTTFLLLFQYCLPLILILVCYLRIFLRLRRRKYMVERTRDNRQKKAKGSKRINAMLASIVAVFALCWLPLNIFNTVFDWNHQAIPSCQHDIIFSACHLTAMASTCVNPIIYGFLNSNFQKQLKSTLYRCRCWGSPESYESFPLSIVST
Protein: Malate synthase G (EC 2.3.3.9) (A5U3K4)
Organism: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Function: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00641}.
Interaction partners:
Sequence:
MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDELQAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSGVDAEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSVPLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIEILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLAAAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFEGIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRKGTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTAWVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDNNCQSILGYVVRWVDQGVGCSKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRASLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKARAAEKPAPSDRAGDDAAR
Protein: Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog) (Q16186)
Organism: Homo sapiens (Human)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16990800}. Nucleus {ECO:0000269|PubMed:16990800}.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome regulatory subunit 6B
- 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome non-ATPase regulatory subunit 4
- 26S proteasome regulatory subunit 7
- Ubiquitin carboxyl-terminal hydrolase isozyme L5
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 5
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 12
Sequence:
MTTSGALFPSLVPGSRGASNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAKPEQKEGDTKDKKDEEEDMSLD
Protein: Peptidase B (EC 3.4.11.23) (Aminopeptidase B) (P37095)
Organism: Escherichia coli (strain K12)
Function: Probably plays an important role in intracellular peptide degradation.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00504}.
Interaction partners:
- Cytosol non-specific dipeptidase
- Cytosol aminopeptidase
- Aminopeptidase N
- Protein IscX
- Glutathione synthetase
- Glutamate--cysteine ligase
- Glutathione hydrolase proenzyme
- Protein SseB
- Glutathione-specific gamma-glutamylcyclotransferase
- Putative glutamate--cysteine ligase 2
Sequence:
MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVVWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA
Protein: Uncharacterized protein (Q580I9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MCRVVDAMARIWTPHSCTSVQQRHAAPHALTTDNIHIRRLSSLRPHQQHHLWRLCQLVTGVTESLSGKGTFVACSVVGGRSQTRCSPSLGLNSGNELCATGVNYALHRSFNAGKTLKGILRGCAEQNALGVAAASGHCYTSINDVYLCAVTCSTPSEGDVSAACGHVCSGEVHKGSGEVSDADASCSGVAFPCAECWRNLSSVAVMRREEGVVGPLNLFVYAQSEASALRSASIAQKNLTARPAPPIDVTVVISG