Protein: Cyclic beta-(1,2)-glucan synthase NdvB (EC 2.4.1.-) (P20471)
Organism: Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Function: Involved in the biosynthesis of cyclic beta-(1,2)-glucan. It seems that NdvB is involved in three enzymatic activities. First, it may catalyze the transfer of the first glucose from UDP-Glc to an unknown amino acid. In the second enzymatic activity (UDP-Glc:beta-(1,2) oligosaccharide glucosyltransferase), it may be responsible for chain elongation. Finally, in the third activity, it may catalyze glucan cyclization and release from the protein. NdvB is also involved in nodule invasion and in bacteroid development.
Subcellular location: Cell inner membrane {ECO:0000255, ECO:0000305|PubMed:2154461, ECO:0000305|PubMed:8830704}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLQNTTQSNLPREPEAKQIDYNDSIRSTYFSIDDLRACGASLAEKGTSALPGFFPFEFRARHRENEKEILRVYRATAADVEAGASITPAAEWLLDNHHVVEEAIQEVRRDFPRRFYRQLPTLSVSGTVIPRTMALAWLYVAHTHSTVTRESITAMVEGFQEHETLKIGELWALPSILRFVLIENLRRIAIRVERSRGMRRKANEVADQLIRLNDPEGCRTLLVESEALAADNTFIAQLLYRMRDGSQSSGAVIAWIEERLERRGTDVEEALVAEQNRLSSGNATMSNIIRSLREIDDTDWAVWFESVSKIDATLREGSDYAALDFGSRNTYRDTIEKLARRSGHSEHEVTEIAIEMVEEAKAAAAVEAPLQEPNVGSFLVGKQRLALEKRIGYSPSIFQHLIRSVRKLDWFAIAGPNILLTILAMIVVYAFVSPMDIPSGAKLIMLLLFALPASEGAMGLFNTVFTLFAKPSRLVGYEFLDGIPEDARTLVVVPCLIAKRDHVDELVRNLEVHYLANPRGEIYFALLSDWADSKSEEAPADTDVLEYAKREIASLSARYAYDGKTRFFLLHRRRLYNEAEGVWMGWERKRGKLHELNLLLRGDRDTSFLQGANMVPEGVQYVMTLDSDTRLMRDAVTKLVGKLYHPINRPVVNPRTQEVVTGYSLLQPRVTPSLTTGSEASAFQRIFTINRGIDPYVFTVSDVYQDIAGEGSFTGKGLYHVDAFEAALKSRIEENAVLSHDLLEGSYARCALVTDIELVEDFPIRYEVEMSRQHRWARGDWQLLPYIFNPKNGLSMLGRWKMYDNLRRSLIPVAWLAASVMGWYYMEPTPALIWQLVLIFSLFVAPTLSLISGIMPRRNDIVARAHLHTVLSDIRAANAQVALRIVFIAHNAAMMADAIVRSLYRTFVSRKLMLEWRTAAQVQSAGHGSIGDYFRAMWTAPALALVSLALAAISDTGLPFIGLPFALIWAASPAVAWFVSQSAETEDQLVVSEEAIEEMRKIARRTWRYFEAFVTAEQNFLPPDNFQETPQPVLAERTSPTNIGVYLLSVMSARSFGWIGFEETITRLEQTIATIDRMPKYRGHLFNWYRTRGLEPMEPRYVSSVDSGNLAGHLIAVSSMCREWAEAPSAHVQGNLDGIGDVAAILKEALNELPDDRKTVRPLRRLVEERIAGFQNALAAVKRERELASIRVINLAVLARDMHKLTVNLDHEVRTVQSGEVATWAGSLVAACEAHIADGVFDLGAIEALRQRLLVLKERARDIAFSMDFSFLFRPERRLLSIGYRVNANELDEACYDLLASEARLTSLFAIAKGDLPTEHWYKLGRPIVPIGARGALVSWSGSMFEYLMPPLVMQERQGGILNQTNNLVVQEQINHGRRLGTPWGISEAAFNARDHELTYQYTNFGVPTLGLKRGLGQNAVIAPYASILACMYDPKSALANLARLREVGALGAYGYHDAVDFTPTRVPEGQKCAVVRNYYAHHHGMSVAAVANVVFNGQLREWFHADPVIEAAELLLQEKAPRDIPVMAAKREPEALGKGQADLLRPEVRVVEDPINQDRETVLLSNGHYSVMLTATGAGYARWNGQSVTRWTPDPVEDRTGTFIFLRDTVTGDWWSATAEPRRAPGEKTVTRFGDDKAEFVKTVGDLTSEVECIVATEHDAEGRRVILLNTGTEDRFIEVTSYAEPVLAMDDADSSHPTFSKMFLRTEISRHGDVIWVSRNKRSPGDPDIEVAHLVTDNAGSERHTQAETDRRRFLGQGRTLAEAAAFDPGATLSGTDGFTLDPIVSLRRVVRVPAGKKVSVIFWTIAAPDREGVDRAIDRYRHPETFNHELIHAWTRSQVQMRHVGITSKEAASFQMLGRYLVYPDMHLRADAETVKTGLASQSALWPLAISGDFPIFCLRINDDGDLGIAREALRAQEYLRARGITADLVVVNERASSYAQDLQHTLDSMCENLRLRGLSDGPRQHIFAVRRDLMEPETWSTLISASRAVFHARNGTISDQIARATSLYSKSSEKKEEGAEMLLPVIREADARTAVELDGGDLDFWNGFGGFAEDGREYAVRLRGGEATPQPWINVISNEQFGFHVSAEGAAFSWSRNSRDYQLTPWTNDAVVNRPGEAIFVRDMASGAVLTPYAALSRRKSALFETRHGLGYSRFLSTQDELEIEAMHTVHRTLPAKLVRLTIRNRSSAARKLRVYGYAEWVLGNNRSRTAPFVLSEWDESAKTLVATNPYSIDYPGRCAFFASDGDIAGYTASRREFLGRAGGILAPQAVISGAELTGSTDVDGDACAALATDITVEAGVERQVTFFLGDADNPDQVRAVLEELRADSFGAALEAAKAFWGDFTGVVKVETPDRAFNHMINHWLPYQALGCRIMARSAFYQASGAFGFRDQLQDTLAFLIHRPALARAQILNAAARQFVEGDVQHWWLPGTDAGVRTMISDDVVWLAHAVAHYCAVTGEEDILKEKVPFITGPALEEGQHDSFYKPDVADEVGDVYEHCARALDLAIHRTGANGLPLILGGDWNDGMNRVGEAGEGTSVWLGWFLAGTLRAFLPYARARKDKPRVALWERHLEALKDALEQAGWDGDYYRRGYYDDDTPLGSAENGECRIDSIAQSWSTLSGEGDKERSLRAMDAVMAELVDPEKRIVRLFTPPLETTKQDPGYIKAYPPGVRENGGQYTHAATWVVLAFAAQERAEEAWRTFRMLNPVSHALSQVDAEHYRVEPYVVAADIYGEGALAGRGGWTWYTGSAGWLYRAGVEGILGIRKRGDKLLIRPVLPSEWPGYSAEVRVNGTTHRISVSRDSKSGEPVVSVNNSVTKNAHEGVLL