wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger protein 219 (Q6IQX8)
Organism: Mus musculus (Mouse)
Function: Transcriptional regulator. Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG-3'. Binds to the HMGN1 promoter and may repress HMGN1 expression (By similarity). Regulates SNCA expression in primary cortical neurons (By similarity). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9. Plays a role in chondrocyte differentiation.
Subcellular location: Nucleus {ECO:0000269|PubMed:20940257}.
Interaction partners:
Sequence:
MEGSRPRILVGHLEPSPPAFDGELDLQRYSNGPGVSGTPGPGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQSSPAAEGLARPQVPSSSAFRCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPPPPPQQEPRSALEPEPEPEPRPEPDREANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSAPARAPQPPDLSLLAYEPLGPALLLAPAPAPAERREPPSLLGYLSVRAGEVRPNGEGADPGGGRSYGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGSLTSLHPNPGEGSGQPAPAAGTQARSTATQEENGLLVGGTRSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSQRGSLQPQSGAKPTQASATWVEGTASTRPPSSSTGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGAGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPTYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER
Protein: Probable hydroxyacylglutathione hydrolase 2, chloroplastic (EC 3.1.2.6) (Glyoxalase 2-4) (Glyoxalase II) (Glx II) (Q8LDW8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Lactoylglutathione lyase GLX1
- Lactoylglutathione lyase
- Probable lactoylglutathione lyase, chloroplastic
- Protein DJ-1 homolog D
- DJ-1 protein homolog F
- DJ-1 protein homolog E
- D-lactate dehydrogenase [cytochrome], mitochondrial
- Protein DJ-1 homolog B
- Monodehydroascorbate reductase 3
- Protein DJ-1 homolog A
Sequence:
MQAISKVSSAASFFRCSRKLVSQPCVRPCVRQLHVRKGLVSGVMKLFSSPLRTLRDAGKSVRISRFCSVSNVSSSLQIELVPCLTDNYAYILHDEDTGTVGVVDPSEAVPVMDALQKNSRNLTYILNTHHHYDHTGGNLELKDRYGAKVIGSAADRDRIPGIDVALKDADKWMFAGHEVHIMETPGHTRGHISFYFPGARAIFTGDTLFSLSCGKLFEGTPEQMLASLQRIIALPDDTSVYCGHEYTLSNSKFALSIEPTNEVLQSYAAYVAELRDKKLPTIPTTMKMEKACNPFLRTENTDIRRALGIPETADEAEALGIIRRAKDNFKA
Protein: Protein C2-DOMAIN ABA-RELATED 5 (Q9LP65)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Stimulates the GTPase/ATPase activities of Obg-like ATPases (By similarity). Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25465408}. Nucleus {ECO:0000269|PubMed:25465408}.
Interaction partners:
- SAUR-like auxin-responsive protein family
Sequence:
MIVSFLYFSSLFPTSLRKINLVAGEKHKDRRMKPSLMDSLLGLLRIRIKRGVNLAVRDLNSSDPYVVVKMAKQKLKTRVIYKNVNPEWNEDLTLSVSDPNLTVLLTVYDYDTFTKDDKMGDAEFGIKPFVNALKMHLHDLPSGTIVTTVQPSRDNCLAEESRVIWSDGKLVQDIVLRLRHVECGEVEAQLQWIDLPGKGL
Protein: Histone acetyltransferase HAC12 (EC 2.3.1.48) (Q9FWQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Histone acetyltransferase GCN5
- Protein HIGH ARSENIC CONTENT 1, mitochondrial
- Probable mediator of RNA polymerase II transcription subunit 15c
- Histone acetyltransferase
- Uncharacterized protein At3g24150
- Transcription initiation factor TFIID subunit 1b
- Transcription initiation factor TFIID subunit 1
- AT4g17080/dl4570w
- Histone acetyltransferase of the MYST family 2
- Histone acetyltransferase MCC1
Sequence:
MNVQAHMSGQRSGQVPNQGTVPQNNGNSQMQNLVGSNGAATAVTGAGAATGSGTGVRPSRNIVGAMDHDIMKLRQYMQTLVFNMLQQRQPSPADAASKAKYMDVARRLEEGLFKMAVTKEDYMNRSTLESRITSLIKGRQINNYNQRHANSSSVGTMIPTPGLSQTAGNPNLMVTSSVDATIVGNTNITSTALNTGNPLIAGGMHGGNMSNGYQHSSRNFSLGSGGSMTSMGAQRSTAQMIPTPGFVNSVTNNNSGGFSAEPTIVPQSQQQQQRQHTGGQNSHMLSNHMAAGVRPDMQSKPSGAANSSVNGDVGANEKIVDSGSSYTNASKKLQQGNFSLLSFCPDDLISGQHIESTFHISGEGYSTTNPDPFDGAITSAGTGTKAHNINTASFQPVSRVNSSLSHQQQFQQPPNRFQQQPNQIQQQQQQFLNQRKLKQQTPQQHRLISNDGLGKTQVDSDMVTKVKCEPGMENKSQAPQSQASERFQLSQLQNQYQNSGEDCQADAQLLPVESQSDICTSLPQNSQQIQQMMHPQNIGSDSSNSFSNLAVGVKSESSPQGQWPSKSQENTLMSNAISSGKHIQEDFRQRITGMDEAQPNNLTEGSVIGQNHTSTISESHNLQNSIGTTCRYGNVSHDPKFKNQQRWLLFLRHARSCKPPGGRCQDQNCVTVQKLWSHMDNCADPQCLYPRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQANVRALARLKNESSAVGSVNRSVVSNDSLSANAGAVSGTPRCADTLDNLQPSLKRLKVEQSFQPVVPKTESCKSSIVSTTEADLSQDAERKDHRPLKSETMEVKVEIPDNSVQAGFGIKETKSEPFENVPKPKPVSEPGKHGLSGDSPKQENIKMKKEPGWPKKEPGCPKKEELVESPELTSKSRKPKIKGVSLTELFTPEQVREHIRGLRQWVGQSKAKAEKNQAMENSMSENSCQLCAVEKLTFEPPPIYCTPCGARIKRNAMYYTVGGGETRHYFCIPCYNESRGDTILAEGTSMPKAKLEKKKNDEEIEESWVQCDKCQAWQHQICALFNGRRNDGGQAEYTCPYCYVIDVEQNERKPLLQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARVQGTSYDEIPTVESLVVRVVSSVDKKLEVKSRFLEIFREDNFPTEFPYKSKVVLLFQKIEGVEVCLFGMYVQEFGSECSNPNQRRVYLSYLDSVKYFRPDIKSANGEALRTFVYHEILIGYLEYCKLRGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKAAKEGIVAETTNLYDHFFLQTGECRAKVTAARLPYFDGDYWPGAAEDIISQMSQEDDGRKGNKKGILKKPITKRALKASGQSDFSGNASKDLLLMHKLGETIHPMKEDFIMVHLQHSCTHCCTLMVTGNRWVCSQCKDFQLCDGCYEAEQKREDRERHPVNQKDKHNIFPVEIADIPTDTKDRDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNVCHLDIESGLGWRCEVCPDYDVCNACYKKEGCINHPHKLTTHPSLADQNAQNKEARQLRVLQLRKMLDLLVHASQCRSPVCLYPNCRKVKGLFRHGLRCKVRASGGCVLCKKMWYLLQLHARACKESECDVPRCGDLKEHLRRLQQQSDSRRRAAVMEMMRQRAAEVAGTSG
Protein: Metabotropic glutamate receptor 7 (mGluR7) (Q68ED2)
Organism: Mus musculus (Mouse)
Function: G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q14831}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q14831}.
Interaction partners:
- Metabotropic glutamate receptor 8
- Metabotropic glutamate receptor 2
- Glutamate receptor ionotropic, kainate 1
- Glutamate receptor 2
- Metabotropic glutamate receptor 3
- Metabotropic glutamate receptor 1
Sequence:
MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPPSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNSPAAKKKYVSYNNLVI
Protein: Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin] (P01966)
Organism: Bos taurus (Bovine)
Function: Involved in oxygen transport from the lung to the various peripheral tissues.
Interaction partners:
- Hemoglobin subunit beta
- Haptoglobin
- Hemoglobin, beta
- Hemoglobin fetal subunit beta
- Globin domain-containing protein
- GLOBIN domain-containing protein
- GLOBIN domain-containing protein
- Apolipoprotein A-I
- Scavenger receptor cysteine-rich type 1 protein M130
- Globin domain-containing protein
Sequence:
MVLSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGAKVAAALTKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLLVTLASHLPSDFTPAVHASLDKFLANVSTVLTSKYR
Protein: Uncharacterized protein, isoform B (Uncharacterized protein, isoform C) (Q0E8T1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Uncharacterized protein
- Serpin 28F
- Aquarius
- AT20289p
- Lectin-29Ca
- Uncharacterized protein
Sequence:
MMNNILVLIGFSSVMLVAGLDDMNCFSLQNEICPNANISFWLYTKENQEGTKLSVFELNRFEFYHHKPLKVLIHGFNGHRDFSPNTQLRPLFLTQDYNLISLDYPKLAYEPCYTEAVHNAKYVARCTAQLLRVLLESGLVKIEDLHLIGLGLGAHVAGFIGQFLPEHKLEHITALDPAKPFYMVKDPALKLDPTDAKFVDVVHTDVTMLGLLDAVGHVDFYLNMGVSQPNCGPINKMETHFCYHNRAADYYAESISSPSGFYGFYCPNFKSFAKGICIPDKNIELMGFHVDPKARGRYFLDTNNGPPYAKGENFTSISRQLKGRTFVNDDIIDKLIGT
Protein: RNA helicase (EC 3.6.4.13) (A2ACQ1)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAAPLGPVKFWKPGTEGPGVSISEERQSVTENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEEAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVRDQLKKLLVKFQVPKVSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ
Protein: Transcription factor HES-2 (Hairy and enhancer of split 2) (P35429)
Organism: Rattus norvegicus (Rat)
Function: Transcriptional repressor of genes that require a bHLH protein for their transcription.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASVCSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSGGPPSLTPASASAPAPSPPVPPPSSLGLWRPW
Protein: Rubredoxin family protein (Q9FFJ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g17180
- Endoplasmic reticulum transmembrane protein
- Endoplasmic reticulum transmembrane protein
- T2P11.11 protein
- Cytochrome P450 71B13
- Calcineurin B-like protein 4
- CBL-interacting serine/threonine-protein kinase 24
- Disease resistance protein
- Late embryogenesis abundant protein At5g17165
- CDGSH iron-sulfur domain-containing protein NEET
Sequence:
MATSGAISGATVSSFFTKTTTTSNPSPKLHSSASLLSQKTVFQGVSLEDSKKSVSEIFAVSERKIGGLNGLRRFEIKARAAASKTIEVEVDKPLGLTLGQKQGGGVVITGVDGGGNAAKAGLKSGDQVVYTSSFFGDELWPADKLGFTKTAIQAKPDSVYFVVSRGAEVDVKKLNKRPAPPRFGRKLTETQKARATHICLDCGFIYTLPKSFDEQPDTYVCPQCIAPKKRFAKYDVNTGKAIGGGLPPIGVIVGLLAGLGAVGALLVYGLQ
Protein: Bradykinin inhibitor peptide (BIP) (P85024)
Organism: Crotalus viridis viridis (Prairie rattlesnake)
Function: Bradykinin inhibitor peptide antagonizes the vasodilatory actions of bradykinin at the B2 bradykinin receptor (BDKRB2).
Subcellular location: Secreted {ECO:0000269|PubMed:16277978}.
Interaction partners:
Sequence:
TPPAGPDVGPR
Protein: Alcohol dehydrogenase YqhD (EC 1.1.1.2) (Q46856)
Organism: Escherichia coli (strain K12)
Function: NADP-dependent ADH activity.
Interaction partners:
- Glycerol dehydrogenase
- Methylglyoxal synthase
- Methylglyoxal reductase DkgA
- NADH-specific methylglyoxal reductase
- HTH-type transcriptional regulator YqhC
- Aldehyde reductase Ahr
- GMP synthase
- Acetaldehyde dehydrogenase
- Aldehyde reductase YahK
- Aldehyde dehydrogenase B
Sequence:
MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR
Protein: Homer, isoform G (M9PEX1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Postsynaptic density {ECO:0000256|ARBA:ARBA00034105}.
Interaction partners:
Sequence:
MSADRTLSEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVEGTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAIDPHTVEPPNMSNTNTQNANPDSPSHKLLNTSDVKADIGSATPSPQPTSGVTGGGGVTISSGGSIVGMHTGPGAGATAEQQLKYENERLKMALAQSCANAKKWEIELATLKNNNIRLTSALQESTANVDEWKRQLHTYKEENIRLKRDMEQLCVGGGVVAAAGGGATEDELRREVATLKARTEQLQKELMQQELELKSANISLREKSNDQTLAKLSEVNGVFAKHLSELYGVQKDMESLIQIAKCT
Protein: L-ascorbate oxidase (AAO) (AO) (ASO) (Ascorbase) (EC 1.10.3.3) (Q8LPL3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ascorbate oxidase involved in a redox system involving ascorbic acid (AsA). The oxidation of AsA represses responses to high salinity and oxidative stress conditions such as vegetative growth and seed production reductions. Negative regulator of defense responses toward incompatible Turnip mosaic virus (TuMV strain UK1) by preventing jasmonic acid (JA)- dependent accumulation of ascorbic acid (AsA, AS) and dehydroascobic acid (DHA).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P37064}.
Interaction partners:
- L-galactono-1,4-lactone dehydrogenase, mitochondrial
- Monodehydroascorbate reductase 3
- L-ascorbate peroxidase 3
- L-ascorbate peroxidase 1, cytosolic
- L-ascorbate peroxidase T, chloroplastic
- L-ascorbate peroxidase 2, cytosolic
- L-ascorbate peroxidase S, chloroplastic/mitochondrial
- Thylakoid lumenal 29 kDa protein, chloroplastic
Sequence:
MAVIVWWLLTVVVVAFHSASAAVVESTWEVEYKYWWPDCKEGIVMAINGQFPGPTIDAVAGDTVIIHVVNKLSTEGVVIHWHGIRQKGTPWADGAAGVTQCPINPGETFTYKFIVDKAGTHFYHGHYGMQRSSGLYGMLIVRSPKERLIYDGEFNLLLSDWWHQSIHAQELALSSRPMRWIGEPQSLLINGRGQFNCSQAAYFNKGGEKDVCTFKENDQCAPQTLRVEPNRVYRLRIASTTALASLNLAVQGHQLVVVEADGNYVAPFTVNDIDVYSGETYSVLLKTNALPSKKYWISVGVRGREPKTPQALTVINYVDATESRPSHPPPVTPIWNDTDRSKSFSKKIFAAKGYPKPPEKSHDQLILLNTQNLYEDYTKWSINNVSLSVPVTPYLGSIRYGLKSAYDLKSPAKKLIMDNYDIMKPPPNPNTTKGSGIYNFAFGIVVDVILQNANVLKGVISEIHPWHIHGHDFWVLGYGEGKFKPGIDEKTFNLKNPPLRNTVVLYPFGWTAIRFVTDNPGVWFFHCHIEPHLHMGMGVVFVEGVDRIGKMEIPDEALGCGLTRKWLMNRGRP
Protein: Ovule protein (Q19576)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MTTGDNKNEGNAVRVQRREYDEDMIPTGTGPVVVVTQSRKMSIYGPNFNYGPIQLRKQRLLEKMKKEAETAMEKRIEELRMAQRILDEQLRSKQVAVQQVLTERKPCNVENTQKNGSTQQYQHHSAVYAIKP
Protein: Rho-associated protein kinase (EC 2.7.11.1) (A0A8C0NIR0)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cell projection, bleb {ECO:0000256|ARBA:ARBA00043945}. Cell projection, lamellipodium {ECO:0000256|ARBA:ARBA00004510}. Cell projection, ruffle {ECO:0000256|ARBA:ARBA00004466}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395}.
Interaction partners:
Sequence:
MSTGDSFEARFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNVDKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVNQNSQLANEKLAQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRILENSKTQMDKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDLLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEESNSMLTKDNELLRKENEELTDKMKRAEEEYKLKKEEEINNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHKNELQMQLASKESDIEQLRAKLLDLSDSTSIASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTSS
Protein: palmitoyl-protein hydrolase (EC 3.1.2.22) (Q9VGV9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Box C/D snoRNA protein 1
Sequence:
MKPALTTVNATGKHTASVIFFHGSGDTGPNVLEWVRFLIGRNLEYPHIKIIYPTAPKQKYTPLDGELSNVWFDRKSVNIAASESKKSMSQCYDAVNQLIDEEVASGIPLNRIVVGGFSMGGALALHTGYHLRRSLAGVFAHSSFLNRGSVVYDSLANGKDESFPELRMYHGERDTLVPKDWGLETFENLTKLGVKGTFHPLRNTLHELKTASITDLQQWIYEKLPPLENQVQNKL
Protein: Syntaxin-42 (AtSYP42) (AtTLG2b) (Q9SWH4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Contributes to the regulation of secretory and vacuolar transport pathways in the post-Golgi network, and to the maintenance of the Golgi apparatus and trans-Golgi network (TGN) morphologies. Vesicle trafficking protein that functions in the secretory pathway and mediates liposome fusion. Required for extracellular resistance responses to a fungal pathogen. Also involved in the protection of chloroplasts from salicylic acid-dependent biotic stress.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:11739776, ECO:0000269|PubMed:15342965, ECO:0000269|PubMed:22307646}; Single-pass type IV membrane protein {ECO:0000255}. Note=SYP42 is found in a different region of the TGN than SYP41. {ECO:0000269|PubMed:11739776}.
Interaction partners:
- Vacuolar protein sorting-associated protein 45 homolog
- Vesicle transport v-SNARE 12
- Syntaxin-61
- Vesicle transport v-SNARE 11
- Vesicle transport v-SNARE 13
- VAMP-like protein YKT62
- VAMP-like protein YKT61
- Syntaxin-51
- Syntaxin-52
- Gamma-soluble NSF attachment protein
Sequence:
MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF
Protein: Protocadherin beta-10 (PCDH-beta-10) (Q9UN67)
Organism: Homo sapiens (Human)
Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MAVRELCFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHAPVFQDKETVLKISENTAEGTAFRLERAQDPDGGLNGIQNYTISPNSFFHINISGGDEGMIYPELVLDKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSPIGFLIVKVWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELVNSYKINIQAMDGGGLSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHLLLVDGFSQPYLPLPEAAPAQAQAEADLLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVRGAETLSQSYQYEVCLTGGPGTSEFKFLKPVISDIQAQGPGRKGEENSTFRNSFGFNIQ
Protein: ornithine decarboxylase (EC 4.1.1.17) (Q58P26)
Organism: Entamoeba histolytica
Interaction partners:
- Arginase
- Peptidase M20 dimerisation domain-containing protein
- Acetylornithine deacetylase, putative
- valine--tRNA ligase
- Aspartate aminotransferase, putative
- Diphthine--ammonia ligase
- Uncharacterized protein
- cysteine-S-conjugate beta-lyase
- Alanine aminotransferase, putative
- Alanine aminotransferase, putative
Sequence:
MKQTSLEVKEFALNLISQFEPENQPLGFWIFDTEGVEKAVERWKKNMPTVRPCFAVKCNPEPHLVKLLGELGCGFDCASLNEIKEVLDLGFNPEDITYSQTFKPYNQLIEASHLGINHTIVDSIDEVQKIAKYAPKMGIMIRIMENDTSAGHVFGEKFGLHDDEVEIVLKEIKDKGLNLDGVHFHVGSDSHNSEVFTKALTKARNTVTLAEQFGMKPYLIDIGGGFSQVAPFEEFAATIEKTIKELEFPERTRFIAEPGRYMASNAFHLVSSLHGKRVRIQNGKKQIEYTSGDGLHGSFGCCIWFEKQKSCECITQKVNENTKMYESIIYGPSCNGSDKVATQELPEMEPGKDWLLFPNMGAYTISMATNFNGFEERNHVIYTLPLKSTKIIQIPKSIECNSVPSLNGIPHYA
Protein: Tyrosyl-tRNA synthetase, putative (Q57XN4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- glutamate--tRNA ligase
- Tyrosyl/methionyl-tRNA synthetase, putative
- leucine--tRNA ligase
- arginine--tRNA ligase
- glutamine--tRNA ligase
- isoleucine--tRNA ligase
- proline--tRNA ligase
- Lysine--tRNA ligase
- Lysine--tRNA ligase
- asparagine--tRNA ligase
Sequence:
MYKYVLQEKSPFCKVLRDVLNMFGVPAENVNSGGECFAVVTGPKTHSGLVPLVSALRKTAVDAKLKEFVGAAPDVAPLVNQWLLWASLLVSNEPTQTFKDSGCTSFMGHLLLQVEKCIDLSDGKKGFLTGGTFPTIADLLLYVAVHNHPLWTPEAYPCVKAWALHTRSNERVAPLIPNLEGDAFSQFNPVATGGKAGATGGGKAKGDKPVFAKPSDEEILRRKQEKEKAKLAKAANAAASAASATTAKDGISSPEKKKEVVPLNPNQLDLRVGRFLNVRRHPNSDRLFVEDMDIGTETRTVVSGLVDYYKAEEVEGTLCITVCNLKPRSLRDINSHGMILCASNETSLRIVQPPEGAKPGDRILFGEAYNKEALLETKQLSGNAATGLLGPLRVDDQSIVRWGDIPAQHPLGVLTVPGITNAIVK
Protein: Zinc finger CCCH domain-containing protein 19 (AtC3H19) (Protein Needed for RDR2-independent DNA methylation) (Q9SIV5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a central role in integrating RNA silencing and chromatin signals in 21 nt siRNA-dependent DNA methylation on cytosine pathway leading to transcriptional gene silencing of specific sequences. Involved in a chromatin-based RNA silencing pathway that encompasses both post-transcriptional gene silencing (PTGS) (e.g. RDR1, RDR6 and AGO2) and transcriptional gene silencing (TGS) (e.g. siRNA-dependent DNA methylation and histone H3) components. Mediates siRNA accumulation at specific chromatin loci. Binds H3K4me0 through its PHD to enforce low levels of H3K4 methylation and gene silencing at a subset of genomic loci.
Subcellular location: Nucleus {ECO:0000269|PubMed:22940247}.
Interaction partners:
- Ubiquitin carboxyl-terminal hydrolase-related protein
- RNA-dependent RNA polymerase 2
- Histone H3-like 3
- Histone H3.3
- Histone H3-like 2
- Histone H3-like 5
- Histone H3.1
- Histone H3-like 4
- Histone H3-like 1
- Histone H3-like centromeric protein CENH3
Sequence:
MDSDSERASLESIKDNSECVHVSNEPNLTATCVDSSVGEEGVTDVNSSAAVSELVPPEQGEGALLNSVPEISERGIPVDVVSSVDGGGEENAAFNIQEIDSVGGDAAAVEEVPLKSSSVVGEGREEEAGASIVKEEDFVAEANLSGDRLEENKEVSMEEEPSSHELSVCEVNGVDSLNDEENREVGEQIVCGSMGGEEIESDLESKKEKVDVIEEETTAQAASLVNAIEIPDDKEVACVAGFTEISSQDKGLDESGNGFLDEEPVKELQIGEGAKDLTDGDAKEGVDVTEDEMDIQVLKKSKEEEKVDSTTELEIETMRLEVHDVATEMSDKTVISSAVVTQFTGETSNDKETVMDDVKEDVDKDSEAGKSLDIHVPEATEEVDTDVNYGVGIEKEGDGVGGAEEAGQTVDLEEIREENQELSKELAQVDETKISEMSEVTETMIKDEDQEKDDNMTDLAEDVENHRDSSVADIEEGREDHEDMGVTETQKETVLGKVDRTKIAEVSEETDTRIEDEDQEKDDEMTDVAEDVKTHGDSSVADIEEGRESQEEMTETQEDSVMADEEPEEVEEENKSAGGKRKRGRNTKTVKGTGKKKEEDVCFMCFDGGDLVLCDRRGCTKAYHPSCVDRDEAFFQTKGKWNCGWHLCSKCEKTATYLCYTCMFSLCKGCAKDAVFFCIRGNKGLCETCMETVKLIERKQQEKEPAQLDFNDKTSWEYLFKDYWIDLKTQLSLSPEELDQAKRPLKGHETNASKQGTASETDYVTDGGSDSDSSPKKRKTRSRSKSGSAEKILSSGDKNLSDETMEWASKELLDLVVHMRRGDRSFLPMLEVQTLLLAYIKRYNLRDPRRKSQVICDSRLQNLFGKSHVGHFEMLNLLDSHFLKKEQNQADDIQGDIVDTEEPNHVDVDENLDHPVKSGKDKKRKTRKKNVRKGRQSNLDDFAAVDMHNINLIYLRRSLVEDLLEDSTAFEEKVASAFVRLRISGNQKQDLYRLVQVVGTSKAPEPYKVGKKTTDYVLEILNLDKTEVISIDIISNQDFTEDECKRLKQSIKCGLINRLTVGDIQEKAIALQEVRVKNLLEAEILRFSHLRDRASDMGRRKEYPYLLKLSNSLTMLTLRECVEKLQLLKSPEERQRRLEEIPEIHADPKMDPDCESEDEDEKEEKEKEKQLRPRSSSFNRRGRDPISPRKGGFSSNESWTGTSNYSNTSANRELSRSYSGRGSTGRGDYLGSSDDKVSDSMWTSAREREVQPSLGSEKPRSVSIPETPARSSRAIAPPELSPRIASEISMAPPAVVSQPVPKSNDSEKIWHYKDPSGKVQGPFSMAQLRKWNNTGYFPAKLEIWKANESPLDSVLLTDALAGLFQKQTQAVDNSYMKAQVAAFSGQSSQSEPNLGFAARIAPTTIEIPRNSQDTWSQGGSLPSPTPNQITTPTAKRRNFESRWSPTKPSPQSANQSMNYSVAQSGQSQTSRIDIPVVVNSAGALQPQTYPIPTPDPINVSVNHSATLHSPTPAGGKQSWGSMQTDHGGSNTPSSQNNSTSYGTPSPSVLPSQSQPGFPPSDSWKVAVPSQPNAQAQAQWGMNMVNNNQNSAQPQAPANQNSSWGQGTVNPNMGWVGPAQTGVNVNWGGSSVPSTVQGITHSGWVAPVQGQTQAYPNPGWGPTGHPQSQSQSQVQAQAGTTGSGWMQPGQGIQSGNSNQNWGTQNQTAIPSGGSGGNQAGYWGNQQQSQNGDSGYGWNRQSGGQQNNFKGQRVCKFFRENGHCRKGASCNYLHN