wanglab/gogpt-training-data huggingface dataset:
Protein: Solute carrier family 40 member 3, chloroplastic (Ferroportin-3) (Iron-regulated transporter 3) (AtIREG3) (Protein MULTIPLE ANTIBIOTIC RESISTANCE 1) (Q8W4E7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable plastid transporter that may play a role in iron chelation, storage or sequestration under limiting iron conditions. In presence of exogenous antibiotics, may allow opportunistic entry of multiple aminoglycoside antibiotics into the chloroplast.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Plastid, chloroplast envelope.
Interaction partners:
- Protein TIC 21, chloroplastic
- Protein MITOFERRINLIKE 1, chloroplastic
- ABC transporter I family member 11, chloroplastic
- Metal transporter Nramp4
- Chaperone protein dnaJ 15
- Translocase of chloroplast 90, chloroplastic
- Translocase of chloroplast 132, chloroplastic
- CDGSH iron-sulfur domain-containing protein NEET
- Chloroplast protein FOR GROWTH AND FERTILITY 2
- Probable metal-nicotianamine transporter YSL4
Sequence:
MVVSMALVRHSPSFDFLFHFPVDRSRFLSPVAFSSVRYHRFHSCRWLSLRSSPSCSRRLNSFSSRCSITNTDVCHEFVTTDDEIHEDLLTPIEDHSIPIVHLDTNISVTESLTLLTECTYVDTVLTALPVLSEEEQTVIAATPAHPEGLYVLYASCLVGNLVEQLWNFAWPSAIAMLYPSLLPVAVMGFVTKLAIIAGGPVVGKFMDYSPRVPTYISLNVIQAAAQVLSAGMIIHAYTVPSTSASSILLQPWFFALLFAGAIDSLCGIASGVAIERDWVVLLAGINRPIALAQANAVLHRIDLLCEIAGTMLFGILLSKYDPVTCLKFAATLMVGSLPTMTALIWLTNKFSSGVLDRPKCSLNSCSAEGSRTNTDSIFDIGMETIKLGWKEYIQQPVLPASLAYVLLYFNIVLTPGSLMTAFLTQRCVNPSVIGGFSGLCAVMGVAATFLSANLVKRVGILKAGAVGLFFQASLLAVAVAVYCSSSLSHKSPLFFFLSMIVLSRLGHMSYGVVGAQILQTGIPSSKANLIGATEISVASLAESLMLGVAIAANDASHFGFLAVLSLLSVVAASLIFCRLLRNPTDEQRRLFSFDPLSN
Protein: Bud6p (A0A1D8PE85)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Spa2p
- Pea2p
- Formin BNI1
- Cell division control protein 42 homolog
- Formin BNR1
- Actin
- Mlc1p
- Profilin
- Kel1p
Sequence:
MSSNNSRLTPDRTSVSSSTNIVSHNSSGKRRSLNTIESSVTRLLVSTKHLLESLTQWARKEADDKFVSDAYVKLGNDFRAAIRAFSNNGIDISDIGNVPQALRIILEAALSEAPSQENLDRFLPSIRNIIVTLLQTLKTKQAKAKAISQEKSTKEELPTENQRPSSLGVEGQQQQQQQQQQQQQRTGDNDSSVERSDALSQLQKGDVLQRRASKRFSAYQYAKLTNFNNPTTSVPKIKPMESPEVRHSKIMETEEPNVTPNKGVESVQEDGNTEEYVLLRINAKTKKAKVSLPVTFASLRLLFVEKFAYSPGAGNFPDIYIQDPRSGVSYELEEHLLPDVKSGTLLCLNETDDQNKSINELNLRLDDLTKKIDTMGSTIIAQVKDSVASVEIPVPTVAASASAVTAKSGNANEANKIGRKDITNLERDFRAIKQLHNSSSENFKETISNITEQLRKFQEIGLEVSQNSNRAYMESCNSKLSDDSDSLITKVDDLQDIMEEMRKDVAQRGVRVSDKQLKHILKDINLAKKSLHDMTLYISKERPVWKKIWEAELDKVCEEQQFLNLQDDLIQDLQDDIKKIEETYNLIEQCSIEQIKGASSKRNKIVANLYIPEPGESLHDLKDAVLNDIVGLTPNHESRLEAIERAEKLREKERDMMKLTKFQEELGDFVEDKKLKRSGGIEEIEKQRQLRDIENLKSSFGGI
Protein: Ubiquitin ligase complex F-box protein UFO1 (Q04511)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity).
Interaction partners:
- Suppressor of kinetochore protein 1
- Cell division control protein 53
- DNA damage-inducible protein 1
- UV excision repair protein RAD23
- Ubiquitin domain-containing protein DSK2
- Homothallic switching endonuclease
- Ubiquitin fusion degradation protein 4
- RING-box protein HRT1
Sequence:
MERPGLVLQDLPPEILINIFSHLDEKDLFTLQELSTHFRNLIHDEELWKNLFKSRVHTTHFPTFSQSSKFSVEYIERTRGLHHWQHNKAIRTKYTIIPTRNWDQPSIERIVFDYPRVAAYNDGTITILQLQNHKRQKKFKKLIYIPCTTPQGCSTMDFNINAAVFGRFDGRVFGKLLSNKSYLTPVMEFTGRHSAGVTAICNSESWDTSREDWSVSGSENGEIIWWCENKLVKMWKVSNRVIWKLAFFKDWTLIMDDEKLYIIHQMQELHSIDIPKDLDEQPMRVRFFKMDFGSMTLVLADLNNVYTISVNPNGNFGNLRKLEMPEQICAVEIDEKTSQREQNWQFAGDDGCYISLLTTQNTLYIINIRDLSSSGLKVQCKISFDEQVYVSQVTNLIVVVALPNVLQILNAMTGELIKTVLKTEKFPEFLKVSQDKIIMGSGNVLNYLKFVSSDSKKHHHSTKGKNTVSNKWNETLNTELQYYDEDEDLRRKRQSEISRLIDAYGGDLELSGDTDEENDIQLRIALLESQEAQARNQAEAGEPVGDDEDEQLRRALEESQLIYETQTNSSANHGNNTNDEIDEDDEEFLRAIRQSRVEDERRRHLRNHTTGRRNGPLSDDNFATYGAAESSERTSTENTIGSSVGVDASNNVDEDLQLAIALSLSEIN
Protein: Transcription factor A, mitochondrial (E5KSU5)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion matrix, mitochondrion nucleoid {ECO:0000256|ARBA:ARBA00004436}.
Interaction partners:
Sequence:
MAFLRSMWGVLSALGRSGAELCTGCGSRLRSPFSFVYLPRWFSSVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIKKQRKYGAEEC
Protein: Putative speedy protein E11 (P0DTA3)
Organism: Homo sapiens (Human)
Function: Acts as a modulator of the nicotinic acetylcholine receptor alpha-7 (CHRNA7) activity.
Interaction partners:
- Ubiquitin-like protein FUBI
- Cyclin-dependent kinase 2
- Cyclin-dependent kinase 1
- M-phase inducer phosphatase 3
- Large ribosomal subunit protein bL36m
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL17m
- Elongation factor Tu, mitochondrial
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein uL23
Sequence:
MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS
Protein: Ladybird late, isoform A (Q9VDA2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MPQRTPSPANSDVSVGSPSPPPLRSLNMKRLRLLRSPISLEHDRQKSSPVRVKSFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNCPPPAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKMSANQSFLKNVNDLTILKTRPVSRSQSLAPQPPTLPPATPALRTHAEHRIG
Protein: Guanine nucleotide-binding protein alpha-7 subunit (G alpha-7) (P34045)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Interaction partners:
- Latrophilin receptor-like protein A
- Guanine nucleotide-binding protein subunit beta
- Metabotropic glutamate receptor-like protein E
Sequence:
MSSTTTNTTTATPAIQVNGNQSSSPQSPSSSTSTLSPPMSPSLLTRYREQKAVNKQIEKQLKEEKKIMDSELKLLLLGTGDSGKSTVVKQMKILHLEGYSQEERINQRQFVYRNIIEIAYSIIRGCGVLNLTIPSQFDSICSSIEEIYETKNYTNLDKNVLKGVAELSKNESFINAANNSGSNFQLHSSSQYFLDDIARFSEEDYIPTDQDILYTRVASTSVSETRFSVRGIKFRMIDVAGQRGHRDKWIHHFSEVTAILFVISLCEYDQVLEEDGKTNRMIESIKVFGDIINQRWFKDIPIILFLNKRDLFAEKIKKTGISICFPDYTGPSDDYEQSLVFLKKKILSANKTSKAVYTNVTTATDTTNIGHVFEAVKDILTRQTMEEGGI
Protein: Methylcytosine dioxygenase TET (EC 1.14.11.80) (E7EQS8)
Organism: Homo sapiens (Human)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
Sequence:
MIQEEQIQLEGSLVDGPEASLMEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSYYGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANGERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNLQAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQQKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVEQIIEKDEGPFYTHLGAGPNVAAIREIMEERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVVRRSSSEEKLLCLVRERAGHTCEAAVIVILILVWEGIPLSLADKLYSELTETLRKYGTLTNRRCALNEERTCACQGLDPETCGASFSFGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEEKLESHLQNLSTLMAPTYKKLAPDAYNNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAHAHRDLHNMQNGSTLVCTLTREDNREFGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVDNCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFGNSQSFTSKYLGYGNQNMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHFMGATSRLPPNLSNPNMDYKNGEHHSPSHIIHNYSAAPGMFNSSLHALHLQNKENDMLSHTANGLSKMLPALNHDRTACVQGGLHKLSDANGQEKQPLALVQGVASGAEDNDEVWSDSEQSFLDPDIGGVAVAPTHGSILIECAKRELHATTPLKNPNRNHPTRISLVFYQHKSMNEPKHGLALWEAKMAEKAREKEEECEKYGPDYVPQKSHGKKVKREPAEPHETSEPTYLRFIKSLAERTMSVTTDSTVTTSPYAFTRVTGPYNRYI
Protein: CG9617 (Q2XYI8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
YQSETKVVITVLLKNAVDKNYAVEITQKRVHMTADGYELDLKLLHPIVVERSSYKAFSTKVEITLAKETGIRWENLEEAIVAAPVKPKAKNWDQLVSEEEKIDEKEAKGEAALTNLFKKIYSSSSPEVQKAMNKSFSESGGTVLSTNWNEVGKERVTVKPPNGTE
Protein: Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (P97315)
Organism: Mus musculus (Mouse)
Function: Could play a role in neuronal development.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P21291}.
Interaction partners:
- Metal regulatory transcription factor 1
- Zyxin
Sequence:
MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGYGQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALVHSE
Protein: Peptidoglycan-recognition protein LF (PGRP-like protein) (Q8SXQ7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Peptidoglycan-recognition protein probably involved in innate immunity by binding to peptidoglycans (PGN) of bacteria and activating the immune response.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Peptidoglycan-recognition protein LC
- Nuclear factor NF-kappa-B p110 subunit
- Protein immune deficiency
- Poor Imd response upon knock-in, isoform A
Sequence:
MPKTVVVTHPGKPINNEKRFRFELLYFCVILLMVVGLAAGYFMWMMSFSTHSPNKGLHILDRSEWLGEPPSGKYPHLKLPVSNIIIHHTATEGCEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQNWPRFTQDPTSLRLLSNETVKIVTRPYWLAQPPIVPLTPLKLPIESVRFVATNTPSCFTQAECTFRVRLLQNWHIESNGYKDINYNFVAAGDENIYEARGWDHSCEPPKDADELVVAFIGPSSSNKKIALELIKQGIKLGHISKNYSLIDDLEKS
Protein: Small ribosomal subunit protein mS35 (28S ribosomal protein S35, mitochondrial) (MRP-S35) (S35mt) (Q8BJZ4)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q2YDF6}.
Interaction partners:
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein mS39
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein mS29
Sequence:
MAAAALQLRQSLCPGPRVLRTFSSVASPAAPRAGPRTASRSERPMRRKALPPRTEKMDTDQDWPSVYPTAAPFKPSAVPLPVRMGYPVKKGVPMAKEGNLELLKIPNFLHLTPVAIKRHCAALKDFCTEWPAALDSDEKCEEHFPVEIDTADYVSSGPSIRNPKARAVTLRVKLSSLNLDNHAKKKLIKLVGERYCKATDVLTITTDRCPLKRQNYDYAVYLLTVLYHESWKTEDWENSKTEEDMDEYVWAKSSSENSVLQTLLQMRAAESSVAPSREELLGTKEVEDYQKCVVRLKNEGENEASLAQYKESVKRLLNLA
Protein: Cysteine protease atg-4.1 (EC 3.4.22.-) (Autophagy-related protein 4 homolog 1) (K8ESC5)
Organism: Caenorhabditis elegans
Function: Cysteine protease required for autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins lgg-1, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (Probable). Its cleavage activity is functionally redundant to atg-4.2, but it cleaves lgg-1 precursors more efficiently than atg-4.2 (Probable). Acts redundantly with atg-4.2 to promote the lgg-1 delipidation to release the protein from membranes, which facilitates multiple events during macroautophagy. Unlike atg-4.2 does not seem to be required for autophagosome maturation.
Subcellular location: Cytoplasm {ECO:0000255, ECO:0000255|RuleBase:RU363115, ECO:0000269|PubMed:22767594, ECO:0000269|PubMed:30880001}.
Interaction partners:
- Protein lgg-1
- Protein lgg-2
- Serine/threonine-protein kinase unc-51
- Ubiquitin-like-conjugating enzyme ATG3
- Ubiquitin-like modifier-activating enzyme ATG7
- Autophagy-related protein 18
- Cysteine protease atg-4.2
- Autophagy-related protein 9
- Ubiquitin-like protein atg-12
- Beclin homolog
Sequence:
MLSILPLAYSNFSRILQYFEQLPVVDKMTEEILKQGVGIVETSLTFEPPFCESFERISIDNFPIFALGKEISKEDGIEAMKKYVTSRFWFTYRRDFSPIGGTGPSTDQGWGCMLRCAQMLLGEVLLRRHIGRHFEWDIEKTSEIYEKILQMFFDEKDALYSIHQIAQMGVTEGKEVSKWFGPNTAAQVMKKLTIFDDWSNIAVHVALDNILVKEDAITMATSYPSEDAVKLIMENGLVDKNRLSLSPGNIIPEWRPLLLMIPLRLGLTTINPCYLSAIQEFFKIPQCVGIIGGRPNHALYFVGMSGSKLFYLDPHYCRPKTESTAKMYAEKDSTATTDDVGFSHLEELVPLPSQTADVYTKMDDSTYHCQMMLWIEYENVDPSLALAMFCETRDEFENLCETLQKTTLPASQPPMFEFLQRRPKYLPKFEPYTGVSMKIEMKEFDDIGAANVKIDDDFEVLDVHTEEEDADEDNDDDVANA
Protein: C-type lectin domain containing 5A (CLEC5A protein) (cDNA FLJ51846, highly similar to C-type lectin domain family 5 member A) (Q14DL9)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MNWHMIISGLIVVVLKVVGMTLFLLYFPQIFNKSNDGFTTTRSYGTVCPKDWEFYQARCFFLSTSESSWNESRDFCKGKGSTLAIVNTPEKLKFLQDITDAEKYFIGLIYHREEKRWRWINNSVFNGNVTNQNQNFNCATIGLTKTFDAASCDISYRRICEKNAK
Protein: Liver-expressed antimicrobial peptide 2 (LEAP-2) (Q969E1)
Organism: Homo sapiens (Human)
Function: Has an antimicrobial activity.
Subcellular location: Secreted.
Interaction partners:
- Hepcidin
- Growth hormone secretagogue receptor type 1
Sequence:
MWHLKLCAVLMIFLLLLGQIDGSPIPEVSSAKRRPRRMTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE
Protein: Myosin phosphatase DMBS-L (Q86RA0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQISRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKFYQKYNELRARIKANSCPILPANANANAAAANKSNNNNNLSSNNYHNNNNNNNKSDLLLGYAAGTTTTTSTPTTTTTTTSSIFNNTHSNTNNTSTTQQQPAAAAAASAANQLYSVQRSASLKDNSMYYRKPTVTIATPTSTAATAINSPSTTVQTPPIRRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSNDKTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFANAQLDAYKSDNHRLKEENAALIRVISKLSK
Protein: Homeobox protein Hox-D3 (Homeobox protein Hox-4.1) (Homeobox protein MH-19) (P09027)
Organism: Mus musculus (Mouse)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Hox-D4
- Homeobox protein Hox-D9
- Homeobox protein Hox-D10
Sequence:
MLFEQGQLTLELPECTMQKAAYYENPGLFGGYGYSKATDTYGYSTPHQPYPPPAAANSLDSDYPSSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGNQPPGLNSEQQPPQPPPPPPPTLPPSSPTNPGSGVPAKKTKGGLSASSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPAGQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYPAPEFEPHPMASNGGGFASANLQGSPVYVGGNFVDSMAPTSGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQGRLPEAPKLTHL
Protein: G protein-coupled receptor kinase 3 (EC 2.7.11.15) (Beta-adrenergic receptor kinase 2) (Beta-ARK-2) (P35626)
Organism: Homo sapiens (Human)
Function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Subcellular location: Postsynapse {ECO:0000250|UniProtKB:P26819}. Presynapse {ECO:0000250|UniProtKB:P26819}.
Interaction partners:
- Beta-arrestin-2
- Beta-adrenergic receptor kinase 1
- Mu-type opioid receptor
- Protein smoothened
- Beta-arrestin-1
- Casein kinase I isoform epsilon
- Casein kinase I isoform gamma-2
- Casein kinase I isoform alpha-like
- Casein kinase I isoform gamma-3
- Casein kinase I isoform delta
Sequence:
MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFNQKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNKPRSGTVELPKPSLCHRNSNGL
Protein: Mitochondrial RNA binding complex 1 subunit (Q38CK0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Mitochondrial SSU ribosomal protein
- Mitochondrial SSU ribosomal protein
- AMP-dependent synthetase/ligase domain-containing protein
- Uncharacterized protein
- Large ribosomal subunit protein uL4m
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MLRRSDLLLKKGWTHNPGRTRRGGKNLAWRPKMSERTLEQFVPLHLAFPRRHPNSWQERQFHLLGYVKWPKEIGFYNAGDNFELTPQAAYRIYKQNCDETFWTRLHNEKTIIHLLPLVEQDPGTNMVLVDDIFRHHLKRFGADHYIYNAVMQAAAFAKDFPRCEQLLAEMRGLGLEPNAQSYVNMMLGARLTGKPRDQAEAFFREGIKTGAISAVMRLDTEFQMWMDQLERLGSFKAKVGYLSVNEEGASPMPRDMWALWGWHRTEAKFISRKQMISEQVQNRVRSGKELVGTVYQKARRQPWAKYNGMFPYDYNGPAQRPAASFVDAPTPTHNAEVCGTAY
Protein: Fibrinogen alpha chain (B8A5L6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Fibrinogen beta chain
- Fgg protein
- Prothrombin
- Plasminogen
- Antithrombin-III
- Protein AMBP
- Alpha-2-HS-glycoprotein 1.
- Heparin cofactor 2 isoform X2, member 1)
- Alpha-2-HS-glycoprotein 2
- Formimidoyltransferase cyclodeaminase.
Sequence:
MKFTHSLLCLFVAVSSALAEEDTVVNPRGARPIEHGFKAQDTCQTKEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSGYDNRYMSLAEQLRQRITDIKIKIDRQLRLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCASYSEFSVDRESYVTLDKQMDNLNAMRVQSVETVSSLGIMKSRPLKDVLVPTIYKSGTGKAEQKLLFGDVGQMQLSLEAEGSTAESAATVSKFPTSGTGSTSQTSSKQCTKSVRKVITHTKDGPVEKVEVSSSGPGCDDLGKLGISDSEFLTAAKDGKDLSRDGLKITVTGGDEKSLTSLSHSTSDLGGFGGDFFKNLGTDNRKYASSSSSTSTKTVSDGSKSYSKTTLTSDPIFGDDLGAFMRGDVEEDMPDIHARSVKSQDDRKAGFVGGDCVEIQQKHVNGGQSGMFKIKPAGSEEVVEVYCDQSTGLGGWTLVQQREDGSVNFNRTWKEYLNGFGQIDKQGKGEIWIGNKFLHLLTQKESLLRVELQDWTGAEAYAEYNIKVGSEAEGFPLTASDYDGDAGDALVRGHPNLGSFLSHAGMKFSTFDRDSDKWEENCAEMYGGGWWYNNCQSANLNGIYYKGGQYDPATKVPYEIENGVVWLPFKPADYSLKVVRMKIRPV
Protein: Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (Q19706)
Organism: Caenorhabditis elegans
Function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. Binds to GC-rich 5'UTRs in cholinergic motor neurons, thereby may play a role in translational regulation of mRNAs involved in neuropeptide signaling and stress response, including hlh-30 isoform d and ncs-2.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03006, ECO:0000269|PubMed:34323215}.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit E
- Eukaryotic translation initiation factor 3 subunit A
- COP9/Signalosome and eIF3 complex-shared subunit 1
- Eukaryotic translation initiation factor 3 subunit D
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 3 subunit H
- Eukaryotic translation initiation factor 3 subunit F
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit K
Sequence:
MTGINAMAPAPEVVSWAEAVEQDNAPHIQEGADGTRTETAFTEVDGVRWKVVTQFKVINKRVPKVVADRKKWVKFGSCKGEPAGPQVATTYVAEEVDMQFTRNRAGEQILDVQEDKQTAKTTSREHCRHCKGNDHWSTHCPYKVMYQLDEEADADKDTEKDRMAMGMRPDGRQIDRNRSDENTCRVTNLPQEMNEDELRDLFGKIGRVIRIFIARDKVTGLPKGFAFVTFESRDDAARAIAELNDIRMYHMVLKVEWTRPSN
Protein: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3b (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily d, member 3b) (Smarcd3b) (B2KL77)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
- Actin-like 6B
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
- PHD finger protein 10
- Actin-like 6A
- Brahma protein-like protein 1
- SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily c, member 1b.
- SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily c, member 2.
- SWI/SNF complex subunit SMARCC1 isoform X1
Sequence:
MASEETAGGARKATKSKLFEFLVHGVRPGMPSGARMPHQGAPMGPPGPPYGGSPAVRPGLTNQSMEASRKRPNPSQQQIQQQAVQNRNRNAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNAAKPDAEDSEGSIASWELRVEGKLLDDPGKMKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTGTTQETDGFQVKRPGDVNVRCTLLLMLDYQPPQFKLDPRLARLLGIHTQTRSSIIQALWQYVKTNKLQDSHDKEYINCDKYFQQIFDCPRLKFSEIPQRLTNLLLPPDPIVINHIISVDPNDQKKTACYDIDVEVEDPLKAQMSSFLLSTANQQEIASLDNKIHETIESINQLKIQRDFMLSFSRDPKGYIQDWLKSQSRDLKLMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQALALRNT
Protein: Heat shock protein DnaJ with tetratricopeptide repeat-containing protein (F4IKX0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Chaperone DnaJ-domain superfamily protein
- Chaperone DnaJ-domain superfamily protein
- AT4g39960/T5J17_130
- Chaperone protein dnaJ C76, chloroplastic
- Chaperone DnaJ-domain superfamily protein
- At3g17830
- At3g13310
- At2g17880
- NAD
- At2g42750/F7D19.25
Sequence:
MSPAAVEIGSPVEKVSSVLNPMENFSAFFPESVHSHDQRTMGSSFSFGFGAGSGQTTKTRHKPRLVKLRKNGREVKKPSFSGEILSGFNPFAPPGKGSLHMNSGNDRDAGQSPGDKCFVFGASGNSSGAKSSPGNATIASLSDEEEFSTPIGDSELDSESIKEHSNGVRGKVDNDRENIRPCSESTIFDATNGFRFDGGVNGSWKSVENPDAVKEFFRRQNGMDKASASKSCSKSNSVQYAHGKNRDDPELNLLADMEKLNISDSRVHGGSDYEEASKSNKTPVFTFSSFGKVDPICKEGAATSEPYSFSSNGFQQSNNASGENPTFHSQTTYGNNLTNTSFATKTFFDDFKVPEWDPSLLKDSLFPEVDRNPVHARSNRSSKDKRSKKVKEKMKQGEPDRCNGQTAEGIEAQEKLNSPGYCSPMDYSPYQGDKTSNQFPTETPLAPSHSREHIDSRSSNDFKVASARDSSLFTAEDHGSTCIPNFSFSASTSQETIRHKKLQAVKKYRRKVNNSLPKSNLNATMRNNQENQPVNTGQAKQDSGSTSMMPDVCEVWRLRGNQAYKNGYMSKAEECYTHGINSSPSKDNSEYSVKPLALCYGNRAAARISLGRLREAISDCEMAASLDPSYIKAYMRAANCHLVLGELGSAVQYFNKCMKSTSSVCLDRRTTIEAAEGLQQAQRVADFTSCASIFLEKRTPDGASDALVPIANALSISSCSDKLLQMKAEALFMIRRYKEVIELCENTLQTAERNFVSAGIGGTTNVNGLGSTYHSLIVWRWNKISKSHFYLGNLEKALDILEKLQQVEYTCNENQEECRESPASLVATISELLRYKNAGNEAVRDRKYMEAVEQYTAALSRNVDSRPFAAICFCNRAAANQALVQIADAIADCSLAMALDENYTKAVSRRATLHEMIRDYDQAASDLQRLISILVKQSDKTKTPETSVDRASSRKELKQARQRLSVMEEKSKEGIHLDFFLIMGVKTSDSAADIKKAYRKAALRHHPDKAAQILVRSESEGPWLKEILEEVHKGADRLFKMIGEAYSVLSDPTKRSDYELEEEIRKARASRESYRSRKAAEASSPPYQTSRRYWKDSWRTNQNTPSWW