wanglab/gogpt-training-data huggingface dataset:
Protein: Prickle homolog 1b (Prickle-like protein 1b) (F2Z4V3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
- Vang-like protein 2
- Vang-like protein
- T-box transcription factor TBX1
- Ankyrin repeat domain 6b
- Dishevelled segment polarity protein 2.
- Dishevelled segment polarity protein 1b
- Cadherin EGF LAG seven-pass G-type receptor 1
- Frizzled-3
- Cadherin, EGF LAG seven-pass G-type receptor 2.
- Dishevelled segment polarity protein 3a
Sequence:
MHYAKCPHPMSLETTSGIWPITRAPDMDSRGAKAFGFQRSSTSDDDSGCALEEYTWVPPGLRAEQVQIYFSCLPEEKVPYVNSPGEKHRIRQLLYQLPPHDNEIRYCQSLSDEERRELHMFSMQRKKEALGRGTPKLLPRALQHNCEHCKENINGGEMAVFASRAGPGPCWHPACFTCYTCHELLVDLIYFYHNGNIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFSCFECETILGGQRYIMKDGRPFCCGCFESLYAEYCEACGENIGVDHAQMTYEGVHWHATDKCFCCAQCKTSLLGCPFLPKDGRIYCSKDCSLGEDVQASDSSDSAFQSARSRESRRSIRMGKSSRPTEQCQQTKLYSATDYRTSSLCGDNTETMCHQLERINFTEDNYWRERDEQEAPEDSVEDWAEHEDYMTQLLLKFGDRGVIHAEDSRAAEPWMVKDTETNRTKPEIKMSGHNLASKKHHTDMYWAQSQDGLGDSAYGSHPGPASARKIQELEMDQGTVPGFWSEPRQWYEDSLECITSELRKADHNIGDSMDSLALSNITGASVDGDSKDRQTIYSLQNMKDQEREIEECDNISNVGTLNSSMLHRSANSLRSLNSELGHEETLGQGAREDDEEDRIPPYFGAEPPSPLNLPVLRRTKSQSQPQSRSQQVKFSDDVLEKGYYGALGLRQPPMSERTRRRTFHIEEEAAAAAERRPANRHHHKRRHSRKTRSENALHLPSKNRGKLHVVPQVISSNMPEPRNGILLNHSAHSQHPYRQTTSDFPQQGMVRLDQFQDFCDDDEEDDWCSTCSSSSSESEEEGFFLGQPIPKPRSQSFHYYTEDYPTRVTALTPPFGSRTKLKKKGHKGKNCIIS
Protein: Rho GTPase-activating protein gacW (GTPase activating factor for raC protein W) (Q54G18)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- F-actin-capping protein subunit beta
- F-actin-capping protein subunit alpha
Sequence:
MTTPVSLSQVEKKTIESILTNKKEEGKLITKVTILNEKKKKLEIKTLILSSNRIFLFTDSKGKLSAEHHYLEITEIASQSENDVTIKFKNQNVMKMNLDASEVLKTLYGTLMSTFPGIKIGKTIIFNITPASRIPSIFQATSFKDIQGCGSFNLTYRSVCDHLGVQPLSSILWDIENLYPFNQVREFNLAEIYQYSFTDLKAILLSLSYNTYFQSFQSNGKLSNEDLNLLAEVFKENSSLQQLTITNSQASKEPIITLLQNVAENKALHLSHINLNNNSLENKGILTLGSSIQTFSNGLTYLNIENTSCSGKGLEAMFGCLTANNVVCGSMTHLNISNNKLESYGTNGLCKFLSKATALQQLLMSNTSPVYSFLKTSSSSIQTLDFSGNKSTTTKESVIDILSFFKQMSHLQTVNLSRIQTTPDDLKLLFSPATSLLKCSSVDLSENDLGDGGIIKLCEIMYPNSNLHHLSIDGNFKTKSKLRARAIEALINLIDDNTSIESLSLASGSGKYQLKGDLMPLLLSLLKNQSLVKLDISGNGVGDSGALAVSKILWKNQTLKSLKCDGNDFSYTALKMIKCSIRRNEKSLTILQLPLSDISTILKNDSNGSSHEKILKTIQDIQTSIVINYPNNIHPIDTSSGGLTPTKQPSIGSLAGVIKKPPIGPPSTPTKSSNPGFQTLPKRPTRGPLYPGRATGGAVTLTDKAQINASTIELPPLVSRSIDLLMEQGISSVGIFRTCASATALKKIKTRFEAGEDIDLKAENVDVDTVAGVLKSYFRELPNPIFPENLHEYFFQAMRQSSNEEIIQSLKDIIDQLSPLECKMIKKLFHLLHLISLEKDVNMMSPENIAICWAPTFFRSFASELLPINSFMIVNYFDIFDPENKPISSDNSGDADTDSTQSTCTTNNNNLVATSLSSPISPSTTPTKSIDNVLHTTVEVSRSPNHERAHTVGPMTSKRPISNNNGVSSNTPPLPNNVTPHHNTMPSRPSASPIKRPPSMGGSLSNFAGIPLSNHSSSGQLNNNNSNNNTTSNSSNSSSGKSSSNPSPIPTPPDSPSMSYIGDGKSTLRSKRFSRVNRVSYSPVLPRAWTNESRTVSSLFQDDLDSNSDSSGPSL
Protein: receptor protein-tyrosine kinase (EC 2.7.10.1) (A0A8I6AIV9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MLNTTMAICRYPLGMSGGHIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGNRWISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRVRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSETSEWEPTAVYFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSGALPTSPMAPTTFDPMLKVDDSNTRILIGCLVAIIFILLAVIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSESSMFNNNHSSSPSEQESNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPAQPNGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLAFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDANIIRLLAVCITEDPLCMITEYMENGDLNQFLSRHEPLSSGSSNATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLPQPAVCPDSVYKLMLSCWRRETKHRPSFQEIHLLLLQQGAE
Protein: Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (3-OST-6) (Heparan sulfate 3-O-sulfotransferase 6) (Q5GFD5)
Organism: Mus musculus (Mouse)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAGSGGLGGGAGDLQGAGTGQGTALRALRAPLALVVLLLSAYCLFALPGRCPPAARAPAPVPAPAEPPHTSLRLRAPGLPVASGPGRRRFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFDRCYDRGLAWYRGLMPRTLDGQITMEKTPSYFVTQEAPRRIHGMSPDTKLIVVVRNPVTRAISDYAQTLSKTPGLPSFRALAFRHGLGPVDTAWSAVRIGLYAQHLDNWLRYFPLSHFLFVSGERLVSDPAGEVGRVQDFLGLKRVVTDKHFYFNATKGFPCLKKAQGSGRPRCLGKSKGRPHPRVPEAVVQRLQAFYRPFNRKFYQMTGQDFGWD
Protein: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0830 (EC 2.1.1.-) (P9WFI3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
Interaction partners:
- Possible deaminase
Sequence:
MVRADRDRWDLATSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAVGMDVYTRLVDWQIPVEGDSEFDPQRMATGMACRTRFFDQFFLDATHSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLGAEPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQDALFDNITALSAPGSRLAFEFVPDTAIFADERWRNYHNRMSELGFDIDLNELVYHGQRGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDDELATAFADLTYSSATLMR
Protein: Phosphoglycerate mutase family protein (Q9LW33)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Putative pentatricopeptide repeat-containing protein At5g52630
- Pentatricopeptide repeat-containing protein At2g25580
- Pentatricopeptide repeat-containing protein At3g12770
- Pentatricopeptide repeat-containing protein At4g30700
- Pentatricopeptide repeat-containing protein At2g02980, chloroplastic
- Pentatricopeptide repeat-containing protein At3g18970
- Putative pentatricopeptide repeat-containing protein At5g09950
- Pentatricopeptide repeat-containing protein At2g29760, chloroplastic
- Putative pentatricopeptide repeat-containing protein At3g05240
- Pentatricopeptide repeat-containing protein At5g19020
Sequence:
MGSSQSTQMEDEEEEEEETDNEEEEEEDNGRSNTRQLDNLLVKKVLEQEPEMLPCHASASPLSPQLSSLGTPRLGPSIKVWDPYNVLSPPPQPPSIFSRIVSGDEDRAVTEVYLISHGESDLNLKPDLIGGRCHVAALTANGKRQARALAVFFKSQGVRFNSVYSSPLDRARSMAVSVCQEMSFPEEHVQSSDAVIEMSLGDWEGCNQAEIYSPETLSLIERCQPDFTAPSGESLRQVEFRMVQFLNGTVSGVAEKLRSDYSSTTNHNETHERDGGVSLASTNWDLLHKHRPSLTRKKSGKSRLQVMTNHEPDDGNSPREEVNHNHTDLSDSSSLISNCVGVFTHSLPIKCLLTGILGCSPVMTHKICVEDSSVTVLQHSWRNGWQIKRMNDTAHLRLL
Protein: Glutathione S-transferase Mu 5 (EC 2.5.1.18) (Fibrous sheath component 2) (Fsc2) (GST class-mu 5) (P48774)
Organism: Mus musculus (Mouse)
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular location: Cytoplasm.
Interaction partners:
- Glutathione S-transferase theta-1
- Glutathione S-transferase omega-1
- Glutathione S-transferase theta-2
- Peroxiredoxin-6
- Peroxiredoxin-6
- Maleylacetoacetate isomerase
- Glutathione S-transferase theta-3
- Epoxide hydrolase 1
- Glutathione S-transferase kappa 1
- Glutathione S-transferase omega-2
Sequence:
MSSKSMVLGYWDIRGLAHAIRMLLEFTDTSYEEKRYICGEAPDYDRSQWLDVKFKLDLDFPNLPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVDIMENQIMDFRMQLVRLCYNSNHENLKPQYLEQLPAQLKQFSLFLGKFTWFAGEKLTFVDFLTYDVLDQNRIFEPKCLDEFPNLKAFMCRFEALEKIAAFLQSDRFFKMPINNKMAKWGNKCLC
Protein: Enolpyruvate transferase domain-containing protein (Q72DT6)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Bifunctional chorismate mutase/prephenate dehydratase
- Uncharacterized protein
- Chorismate synthase
- Prephenate dehydrogenase
- Leucine-binding protein domain-containing protein
- FG-GAP repeat protein
- Lipoprotein, putative
- Uncharacterized protein
- GAF domain protein
Sequence:
MIDFVKALNQSGASISWDEAGNVHAKAGCPLDFSDKVVYIGEDALNLYLLIFLAIGAQSHLKITGGAALKLADLSALSHFLPGLGARLTNVVPKTKGLPVRLESSGILPDDVTVPDDLPAEALCALLLAASFWPGTVTLRLPATPVSASCLAAVLPLLHEAGIKATADGDTVRITSGTMTIPAEPALAMEPLVATYLLGLPAVAGGNVRLTGLWPAACAEAEAAIALLKAGGLEVKRDKDGIASTYAAVPGDMDAPLATLPPAYAPLAVLLAAATFASEKPARMPALPAGTDALAATGLLGQLGLEADAEDGALTRVETDIPGAGWASPAPEWSMALAFGSFLRSGLRLANPGNITELMPAFWALFNGLPSPDLKPKPKEIIDAKPARRRIIAG
Protein: Protein BONZAI 1 (COPINE 1) (Q941L3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Negative regulator of cell death and defense responses. Negative regulator of several R genes, including SNC1. May have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane at low temperature. Exhibits calcium-dependent phospholipid binding properties.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=Calcium enhances the association with membranes. {ECO:0000269|PubMed:11544183, ECO:0000269|PubMed:20634289}.
Interaction partners:
- BON1-associated protein 1
- Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380
- Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1
- Calcium-transporting ATPase 10, plasma membrane-type
- BON1-associated protein 2
- Lipase-like PAD4
- DCD
- Protein EDS1
- Suppressor of RPS4-RLD 1
- BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1
Sequence:
MGNCCSDVASGAGATAGVGGSGSSAALGATNDALDYYLKSKGFNGLFSQIELSFSASNLRDRDVLSKSDPMVVVYQKEKDATLSEVFRSEVVLNSLAPKWIKKFIVAYHFETVQTLVFRVYDVDTKFQNSREEMLKLDEQQFLGEATCALSEIITKSTRTSTLELKRKDGFAPQAQPHHGKLIIHAEESLASKISTEIVFRCSNLESKDLFSKSDPFLVVSKIVEHGTPIPVSKTEVRKNDLNPIWKPVFLSVQQVGSKDSPVIIECSDFNSNGKHSLIGKVQKSLSDLEKLHLAGQGINFSLPTGAGQNKVLKSQLFVDKFTETVHHTFLEYLASGFELNFMVAIDFTASNGNPRLPDSLHYIDPSGRLNAYQRAIMDVGEVLQFYDSDKRFPAWGFGARPIDAPVSHCFNLNGSSSYSEVDGIQGIMTSYTSALFNVSLAGPTLFGPVINAAAMIASASLAQGSRKYYVLLIITDGVITDLQETKDALVSASDLPLSILIVGVGGADFKEMEILDADKGERLESSSGRLASRDIVQFVALRDVQYGEISVVQALLAELPSQFLTYMRIRNMKPIPP
Protein: General transcription factor IIH subunit 4 (Q9VUR1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364024}.
Interaction partners:
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription and DNA repair factor IIH subunit TFB5
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit
- CDK-activating kinase assembly factor MAT1
- General transcription and DNA repair factor IIH helicase subunit XPD
- Cyclin-H
- General transcription factor IIE subunit 1
- Cyclin-dependent kinase 7
Sequence:
MADTKSGSGRHSAAGGSGNAVLSPLGQGPANLECKDFQEYLRTRQTPESLEKLYNYPPICLAVFRELPEIARQFIIRILFVDQPVPQAVVTSWGAQRCAKEQAEATSCLTALNVWRVTAIPGGLSAWELSPTFKKSVRQVLLGGGKPWPMTNTLDKDSKPRDIAFLDTYAMSRWRCVLHYMVGTGNRNGTDAEAISPDAVRILLHANLMKRDERDGITITRQGFQFLLLDTRAQVWHFMLQYLDTCEERGISLPECLSMLFQLSFSTLGRDYSSEGMNSQMLTFLQHLREFGLVFQRKRKEGRFYPTRLALNVTSKEAAATASVAMDEEATQDCGYIVVETNYRVYAYTDSPLQVAVLGLFTELLYRFPNLVVGVLTRDSVRQALRGGITAEQIVSYLEQYAHPNMRMVESAIHSKSCLPPTVVDQIKLWELERNRFTYTEGVLYNQFLSHTDFVTLRDYAQSIHMLVWQNERTRTMVVQKNGHDDVKRYWKKYSKSGV
Protein: NF-kappa-B essential modulator (IkB kinase-associated protein 1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (NF-kappa-B essential modifier) (Q58EN3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVQPQPSGGCTLQYELNGEETAGSEGQVSLMASSQGSLRVPADLAGNEIVQKLITDNHQLREALKRSNDALKERCEEMEGWQRRSREEREFLSCRFREARELVQRLAQENQSLLGQLNLSVSQAGSLGISKETGSQDQELKCTNAEKNVLIDSPEVLNAAVLTECAEGDTDRHTMPQSLPAVGSNDFLKLLKSHKEKLEEGMRALRRKNEELEKEKAENEKERENLLAALEQLRSKLSQNVGVTEESVQPTCAVTVPAERYRELQEKLDCLQKNSFQRDRTEALLKQKEKEFVQVQKDSEALRSQVTSLLGELNERQNWLEKSEAEKRTLEDKLVTKSERLQTVEREMEQQKKQHSVTVDNLLLKTQNLEAALKNERLVIVEERRKLAQLQHAYTCLFQDYDNKLKSEKQANHRGGEADTLANRLGEAEKALALKQEHIDKLKEEMEQLRAKLETIPVLNHQAEIYKMDFLAEREAREKLNQKKEELQEDLNKALVEIERFKQERTSRARIEEMQQRHLEDYRPRPHPPPPAAPFPGPAMFNSAQPPSARRRDEDQEELPDYRCPKCMYKAPDMDTLQIHVMDCIQ
Protein: Probable pectin lyase A (PLA) (EC 4.2.2.10) (A2R3I1)
Organism: Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
Function: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MKYSTIFSAAAAVFAGSAAAVGVSGSAEGFAEGVTGGGDATPVYPDTIDELVSYLGDDEARVIVLTKTFDFTDSEGTTTGTGCAPWGTASACQVAIDQDDWCENYEPDAPSISVEYYNAGVLGITVTSNKSLIGEGSSGAIKGKGLRIVSGAENIIIQNIAVTDINPKYVWGGDAITLDDCDLVWIDHVTTARIGRQHYVLGTSADNRVSLTNNYIDGVSDYSATCDGYHYWGIYLDGDADLVTMKGNYIYHTSGRSPKVQDNTLLHCVNNYFYDISGHAFEIGEGGYVLAEGNVFQNVDTVLETYEGAAFTVPSTTAGEVCSTYLGRDCVINGFGSSGTFSEDSTSFLSDFEGKNIASASAYTSVASSVVANAGQGNL
Protein: Oxaloacetate tautomerase FAHD2, mitochondrial (EC 5.3.2.2) (Fumarylacetoacetate hydrolase domain-containing protein 2) (FAH domain-containing protein 2) (Q9LUR3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable acylpyruvase. Binds copper in vitro.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:20018591}.
Interaction partners:
- Fumarylacetoacetase
- Oxaloacetate tautomerase FAHD1, mitochondrial
- Homogentisate 1,2-dioxygenase
- Fumarate hydratase 2
- Fumarate hydratase 1, mitochondrial
- Succinate dehydrogenase flavoprotein subunit 1, mitochondrial
- Succinate dehydrogenase flavoprotein subunit 2, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit 2, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit 3, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit 1, mitochondrial
Sequence:
MATSMIQRLFKQGTKIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIPHPLDSLHHEVELAVVIGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLAKGQDTFTPISSVLPKAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFKGDVILTGTPEGIGPVKIGQKITAGITGLSEVQFDVGRRLKPLLR
Protein: SNW/SKI-interacting protein (AtSKIP) (Protein EARLY FLOWERING AND INSENSITIVE TO PHOTOPERIOD 1) (SNW domain-containing protein) (O80653)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Splicing factor involved in post-transcriptional regulation of circadian clock and flowering time genes. Associates with the pre-mRNA of PRR7, PRR9, ELF3 and GI, and is necessary for the regulation of their alternative splicing and mRNA maturation. Probably involved in splice site recognition.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:19765229, ECO:0000269|PubMed:22942380}.
Interaction partners:
- Pre-mRNA-processing-splicing factor 8A
- DExH-box ATP-dependent RNA helicase DExH12
- Tetratricopeptide repeat
- Nuclear protein-like
- Crooked neck protein, putative / cell cycle protein
- AT3G18790 protein
- Peptidyl-prolyl cis-trans isomerase CYP18-2
- Pre-mRNA-splicing factor SPF27 homolog
- Cell division cycle 5-like protein
- ATPase E1
Sequence:
MKSLNDLPAPKSTTTTYYDHSNDAWFKNRVTESETVKSSSIKFKVVPAYLNRQGLRPKNPEDFGDGGAFPEIHLPQYPLLMGKNKSNKPGAKTLPVTVDAQGNVVFDAIVRQNENSRKIVYSQHKDIIPKFLKNEGDLGTVVDEEEELQKEIQETAEETKAAIEKIVNVRLSAAQPSNIARQSGDSQYIKYKPSQQSSAFNSGAKERIIRMVEMPVDPLDPPKFKHKRVPRASGSPPVPVMHSPPRPVTVKDQQDWKIPPCISNWKNPKGYTIPLDKRLAADGRGLQDVQINDNFAKLSEALYVAEQKAREAVSMRSKVQKEMVMKDKERKEQELRALAQKARSERTGAAMSMPVSSDRGRSESVDPRGDYDNYDQDRGREREREEPQETREEREKRIQREKIREERRRERERERRLDAKDAAMGKKSKITRDRDRDISEKVALGMASTGGKGGGEVMYDQRLFNQDKGMDSGFAADDQYNLYDKGLFTAQPTLSTLYKPKKDNDEEMYGNADEQLDKIKNTERFKPDKAFTGASERVGSKRDRPVEFEKEEEQDPFGLEKWVSDLKKGKKPLDKIGSGGTMRASGGGGSSSRDDDHGGSGRTKINFERSDRR
Protein: Protein kinase, putative (C4LSU1)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Interaction partners:
- SH3 domain-containing protein
- Rho family GTPase.
- DH domain-containing protein
Sequence:
MSFFKKKKDEEELIISDPTDFEQITHVELGDSGLTGFPPEWREKLIKAGLTEAEINTNEDSAKLVAASGISNDNGNRTTFTNGKEEEDDITQYTTAADPDENYENLAKTIYGDEDEYMATRKSDGMEVSLRRMRITKKTKRAVVREVVVLSKCVNDNIVKYVECYLINDMLWLVTELMDAGELTNAIDLHPTLPMKECHIAYVCKRVLQGLVYLHKMGIIHRDIKSDNILLHHKGTVKLSNFGFAAILTSAHPNRNSIVGTPFWMAPELIKSQNYDTKVDIWSLGITCREMADGTPPYMDFPPMKALFQITTKGIPPLEGIWDDKFKNFLNKCLNPDASKRASAEELLQDPFISMECTEEEFIDFLTQVRKISDEEMAQEDDEIPAEE
Protein: 2-oxoglutarate-dependent dioxygenase AOP3 (EC 1.14.11.-) (Q945B4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: 2-oxoglutarate-dependent dioxygenase involved in glucosinolates biosynthesis. Catalyzes the conversion of methylsulfinylalkyl glucosinolates to hydroxyalkyl glucosinolates.
Interaction partners:
Sequence:
MGSCSPQLPLICLSDQTLKPGSSKWVKVRSDVRKALEDYGCFEAKIDQVSMELQGSVLKAMQELFALPTEAKQRNVCPKPFAGYFSHNGLSESFGIKDANILEKAHEFTQQLWPEGNKSIKMIQLYAEKLAELDMMVRRLILESYGIEYFIDEHLNSTYYRMRLMKYIARPDNDITAAVGANVDNGANDNADGDANVNDDGASIGVKVNVDVGDDVNDNDSVNIGVGVDINVETNVNGDLDAEANGDATAWVVGAVSGNASVGAKEANVDAELGLPSHTDKSLSGIIYQHQIDGLEVKTKEGKWIRVKPAPNTVIVIAGDALCALMNGRIPSPYHRVRVTERKKTRYAAALFSYPKEGYIIDSPKELVDEKHPRAFKPFDFVDLFNFYHTEAGRRAPSTLQAFCGVSAGK
Protein: Putative pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD) (P38744)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Protein SPH1
- Deoxyhypusine synthase
Sequence:
MHNKIVRIASSALTGGKLLEKLKPLTRWEVQWDPNKTKCLGITREVTFKDYETTWAFLTRVSMRSHLWGHHPLIHTSYTWVKLELHTHDIDPKDGAHSQLSDIDVRMAKRIDSYIDEMTT
Protein: Capping protein, Arp2/3 and myosin-I linker protein 3 (Capping protein regulator and myosin 1 linker protein 3) (Leucine-rich repeat-containing protein 16B) (Q8ND23)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21102520}. Cell membrane {ECO:0000269|PubMed:26578515}.
Interaction partners:
Sequence:
MAKPSVELTRELQDSIRRCLSQGAVLQQHHVKLETKPKKFEDRVLALTSWRLHLFLLKVPAKVESSFNVLEIRAFNTLSQNQILVETERGMVSMRLPSAESVDQVTRHVSSALSKVCPGPGCLIRRGNADTPEGPRDTSPNSETSTSTTHSVCGGFSETYAALCDYNGLHCREEVQWDVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQVLHTLSKSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLHALTLSHNPIEDKGFLSLSQQLLCFPSGLTKLCLAKTAISPRGLQALGQTFGANPAFASSLRYLDLSKNPGLLATDEANALYSFLAQPNALVHLDLSGTDCVIDLLLGALLHGCCSHLTYLNLARNSCSHRKGREAPPAFKQFFSSAYTLSHVNLSATKLPLEALRALLQGLSLNSHLSDLHLDLSSCELRSAGAQALQEQLGAVTCVGSLDLSDNGFDSDLLTLVPALGKNKSLKHLFLGKNFNVKAKTLEEILHKLVQLIQEEDCSLQSLSVADSRLKLRTSILINALGSNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLRTILWDRNNTSALGFLDIARALESNHTLRFMSFPVSDISQAYRSAPERTEDVWQKIQWCLVRNNHSQTCPQEQAFRLQQGLVTSSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARDLIKDAKNSRALFPSLYELGHVLANDGPVRQRLESVASEVSKAVDKELQVILESMVSLTQELCPVAMRVAEGHNKMLSNVAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVVTYLTSSIVDEILQELYHSHKSLARHLTQLRTLSDPPGCPGQGQDLSSRGRGRNHDHEETTDDELGTNIDTMAIKKQKRCRKIRPVSAFISGSPQDMESQLGNLGIPPGWFSGLGGSQPTASGSWEGLSELPTHGYKLRHQTQGRPRPPRTTPPGPGRPSMPAPGTRQENGMATRLDEGLEDFFSRRVLEESSSYPRTLRTVRPGLSEAPLPPLQKKRRRGLFHFRRPRSFKGDRGPGSPTTGLLLPPPPPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGGRGPSFRRKMGTEGSEPGEGGPAPGTAQQPRVHGVALPGLERAKGWSFDGKREGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKEGTLFPERTLPARNAKLQDPALAPWPPKPVAVPRGRQPPQEPGVREEAEAGDAAPGVNKPRLRLSSQQDQEEPEVQGPPDPGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPTGTSEPGTD
Protein: Guanine nucleotide exchange factor sopE2 (Effector protein sopE2) (Toxin sopE2) (Q7CQD4)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Activator for CDC42 by directly engaging this Rho GTPase and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Also activates NF-kB, p38 and ERK kinases, which are known to be involved in the induction of IL-8 expression. Chaperone InvB is required for secretion, translocation and stabilization of intracellular levels of sopE2.
Subcellular location: Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 T3SS).
Interaction partners:
- Cell invasion protein SipA
- Inositol phosphate phosphatase SopB
- SPI-1 type 3 secretion system translocon protein SctE
- E3 ubiquitin-protein ligase SopA
- Cell invasion protein SipD
- Secreted effector protein SopD
- SPI-1 type 3 secretion system translocon protein SctB
- Chaperone protein SicA
- Secreted effector protein SptP
- Inner membrane protein
Sequence:
MTNITLSTQHYRIHRSDVEPVKEKTTEKDIFAKSITAVRNSFISLSTSLSDRFSLHQQTDIPTTHFHRGNASEGRAVLTSKTVKDFMLQKLNSLDIKGNASKDPAYARQTCEAILSAVYSNNKDQCCKLLISKGVSITPFLKEIGEAAQNAGLPGEIKNGVFTPGGAGANPFVVPLIASASIKYPHMFINHNQQVSFKAYAEKIVMKEVTPLFNKGTMPTPQQFQLTIENIANKYLQNAS
Protein: Protein PIGBOS1 (PIGB opposite strand protein 1 homolog) (C0HLN0)
Organism: Rattus norvegicus (Rat)
Function: Plays a role in regulation of the unfolded protein response triggered by endoplasmic reticulum (ER) stress resulting from the presence of unfolded proteins in the ER lumen.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:31653868}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MLRRLTRPQLLFAAALGVAGGMYIYQPIFEQYSRDQKELKEKVKILQESEEKRS
Protein: Beta-mannanase (EC 3.2.1.78) (Endo-1,4-beta-mannosidase) (Q5YEX6)
Organism: Bacillus sp. N16-5
Interaction partners:
Sequence:
MKKKLSQIYHLIICTLIISVGIMGITTSPSEASSGFYVDGNTLYDANGQPFVMKGINHGHAWYKDTASTAIPAIAEQGANTIRIVLSDGGQWEKDDIDTVREVIELAEQNKMVAVVEVHDATGRDSRSDLDRAVDYWIEMKDALIGKEDTVIINIANEWYGSWDGAAWADGYIDVIPKLRDAGLTHTLMVDAAGWGQYPQSIHDYGQDVFNADPLKNTIFSIHMYEYAGGDANTVRSNIDRVIDQDLALVIGEFGHRHTDGDVDEDTILSYSEETGTGWLAWSWKGNSAEWDYLDLSEDWAGNHLTDWGNRIVHGANGLQETSKPSTVFTDDNGGAPEPPTTTTLYDFEGSTQGWHGSNVMGGPWSVTEWGASGNYSLKGDVNLSSNSSHELYSEQSRNLHGYSQLNATVRHANWGNPGNGMNARLYVKTGSDYTWYSGPFTRINSSNSGTTLSFDLNNIENSHHVREIGVQFSAADNSSGQTALYVDNVTLR
Protein: tRNA methyltransferase 10 homolog A (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 2) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10A) (Q8TBZ6)
Organism: Homo sapiens (Human)
Function: S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.
Subcellular location: Nucleus {ECO:0000269|PubMed:24204302}. Nucleus, nucleolus {ECO:0000269|PubMed:24204302}.
Interaction partners:
- tRNA
- tRNA
- tRNA
- tRNA
- tRNA pseudouridine
- tRNA
- tRNA
- Pseudouridylate synthase 1 homolog
- RNA cytosine C
- tRNA
Sequence:
MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMNSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGGSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
Protein: Fus RNA binding protein (A0A8I6AN32)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASNDYTQQATQSYGAYPTQPGQGYSQQSNQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNTGYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQSGGYGQQSGYGGQQQSYGQQQSSYNPPQGYGQQNQYNSSSGGGGGGGQQRAGDWKCPNPTCENMNFSWRSECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY
Protein: Myosin, heavy polypeptide 13, skeletal muscle (M0QWL0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
XFGRPVGSWFTLKLCHHSWFPLKDSQLHLDDAQRSNEDLKEQLAIVERRNGLLQEELEEMKVALEQTERTRRLSEQELLDSSDRVQLLHSQNTSLINTKKKLEADLAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELESELDAEQKRGAEALKGAHKYERKVKEMT