wanglab/gogpt-training-data huggingface dataset:
Protein: GREB1-like protein (Growth regulation by estrogen in breast cancer 1-like protein) (Q9C091)
Organism: Homo sapiens (Human)
Function: Plays a major role in early metanephros and genital development.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MGNSYAGQLKSARFEEALHNSIEASLRCSSVVPRPIFSQLYLDPDQHPFSSADVKPKVEDLDKDLVNRYTQNGSLDFSNNLTVNEMEDDEDDEEMSDSNSPPIPYSQKPAPEGSCTTDGFCQAGKDLRLVSLCMEQIDIPAGFLLVGAKSPNLPEHILVCAVDKRFLPDDHGKNALLGFSGNCIGCGERGFRYFTEFSNHINLKLTTQPKKQKHLKYYLVRSSQGVLSKGPLICWKECRSRQSSASCHSIKPSSSVSSTVTPENGTTNGYKSGFTQTDAANGNSSHGGKGSASSSTPAHTGNYSLSPRPSYASGDQATMFISGPPKKRHRGWYPGSPLPQPGLVVPVPTVRPLSRTEPLLSAPVPQTPLTGILQPRPIPAGETVIVPENLLSNSGVRPVILIGYGTLPYFYGNVGDIVVSPLLVNCYKIPQLENKDLEKLGLTGSQFLSVENMILLTIQYLVRLGPDQVPLREEFEQIMLKAMQEFTLRERALQIGAQCVPVSPGQLPWLARLIASVSQDLVHVVVTQNSLAEGISETLRTLSEMRHYQRLPDYVVVICASKIRGNEFCVVVLGQHQSRALAESMLTTSEFLKEISYELITGKVSFLASHFKTTSLGDDLDKLLEKMQQRRGDSVVTPFDGDLNECVSPQEAAAMIPTQNLDLDNETFHIYQPQLTVARKLLSQVCAIADSGSQSLDLGHFSKVDFIIIVPRSEVLVQQTLQRIRQSGVLVDLGLEENGTAHQRAEKYVVRLDNEIQTKFEVFMRRVKQNPYTLFVLVHDNSHVELTSVISGSLSHSEPSHGLADRVINCREVLEAFNLLVLQVSSFPYTLQTQQSRISSSNEVHWIQLDTGEDVGCEEKLYFGLSEYSKSLQWGITSPLLRCDETFEKMVNTLLERYPRLHSMVVRCYLLIQQYSEALMALTTMASLRDHSTPETLSIMDDLISSPGKNKSGRGHMLIIRVPSVQLAMLAKERLQEVRDKLGLQYRFEIILGNPATELSVATHFVARLKSWRGNEPEEWIPRTYQDLDGLPCIVILTGKDPLGETFPRSLKYCDLRLIDSSYLTRTALEQEVGLACCYVSKEVIRGPTVALDLSGKEQERAAVSENDSDELLIDLERPQSNSSAVTGTSGSIMENGVSSSSTADKSQKQSLTPSFQSPATSLGLDEGVSASSAGAGAGETLKQECDSLGPQMASSTTSKPSSSSSGPRTLPWPGQPIRGCRGPQAALPPVVILSKAAYSLLGSQKSGKLPSSSSLLPHADVAWVSSLRPLLNKDMSSEEQSLYYRQWTLARQHHADYSNQLDPASGTRNFHPRRLLLTGPPQVGKTGSYLQFLRILFRMLIRLLEVDVYDEEEINTDHNESSEVSQSEGEPWPDIESFSKMPFDVSVHDPKYSLMSLVYTEKLAGVKQEVIKESKVEEPRKRETVSIMLTKYAAYNTFHHCEQCRQYMDFTSASQMSDSTLHAFTFSSSMLGEEVQLYFIIPKSKESHFVFSKQGKHLESMRLPLVSDKNLNAVKSPIFTPSSGRHEHGLLNLFHAMEGISHLHLLVVKEYEMPLYRKYWPNHIMLVLPGMFNNAGVGAARFLIKELSYHNLELERNRLEELGIKRQCVWPFIVMMDDSCVLWNIHSVQEPSSQPMEVGVSSKNVSLKTVLQHIEATPKIVHYAILGIQKWSSKLTSQSLKAPFSRCHVHDFILLNTDLTQNVQYDFNRYFCEDADFNLRTNSSGLLICRFNNFSLMKKHVQVGGQRDFIIKPKIMVSESLAPILPLQYICAPDSEHTLLAAPAQFLLEKFLQHASYKLFPKAIHNFRSPVLAIDCYLNIGPEVAICYISSRPHSSNVNCEGVFFSGLLLYLCDSFVGADLKKFKFLKGATLCVICQDRSSLRQTIVRLELEDEWQFRLRDEFQTANSSDDKPLYFLTGRHV
Protein: Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) (Q8LHH9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in the RNA silencing pathway. Probably required for the generation of small interfering RNAs (siRNAs). Regulates shoot apical meristem (SAM) initiation and maintenance and leaf polarization through the trans-acting siRNAS (ta-siRNAs) pathway which probably modulates the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes.
Interaction partners:
- Os05g0230200 protein
- Os09g0555200 protein
- Os04g0572600 protein
- DNA-directed RNA polymerase
- Os07g0495900 protein
Sequence:
MRSPRGGAAAQPSGRRGDTTAAAAGDLVTTQVSLGGFDAGVAAGDLADFLEHEVGLVWRCRVKTSWTPPDSYPDFALPTAPASASAAAAPPRYDRVPPHAFVHFARPEGARRAADLAGETRLILRGKPLRVASAPDSSLRVSRRSSIAPFRFPDVRLEVGALPSPGAFLAAWRGPDAGLDLSVDPFDGCCRLVFTRDTAFTFPGFREVAAIRCDVKLEFPVRDVLEVRLYRLDCSLLLRLAAAPLVHYRTADDDFHEPVPFDLLDDDDPWIRTTDITPSGAIGRCGVYRISFSARFWPKMDRALDYMRERRVAIVDCGGGWGPRRGLTVRDELEFGEPMQDVFFCLQHAEGLKFPLLFMVNALVHKGIINQHQLTPEFFSLLGRSEENVNVAALRDFWGDKFPVFDACGRLKKALNRVARNPKLLCSKVGDDHAEVRRLVITPTRAYCLPPEVERSNRVLRHYHEVADRFLRVTFMDEGMQVLNNNVLNSFTAPIVKDLMSNFFQQKTTVYKRVRMLLTEGFHMCGRKYSFLAFSSNQLRDKSAWFFAEDRKTTVEAIRKWMGRFTSKNVAKHAARMGQCFSSTYATVTMRPDEVDESFDDVVHNEYIFSDGIGKITPDLALEVAERLQLTDNPPSAYQIRFAGFKGVIAVWQGHGDGTRLFLRPSMRKFESNHLVLEVVSWTKFQPGFLNRQIIILLSSLNVPDSIFWQMQETMLSNLNNILSDRDVAFEVLTTSCADDGNTAALMLSAGFEPRTEPHLKAMLLAIRSAQLQDLLEKARIFVPKGRWLMGCLDELGVLEQGQCFIRATVPSLNSYFVKHGSRFSSTDKNTEVILGTVVIAKNPCLHPGDVRILEAVDVPELHHLVDCLVFPQKGERPHANEASGSDLDGDLYFVTWDEKLIPPGKKSWNPMDYSPPEAKQLPRQVSQHDIIDFFLKNMISENLGRICNAHVVHADLSEYGAMDEKCIHLAELAATAVDFPKTGKLAIMPPHLKPKVYPDFMGKEDGQSYKSEKILGRLYRSIQEASNGDVVSQEVCTPNDLPYDIDLEVPGASDFLASAWQCKCSYDAQLSALLSQYRVRTEAELVTGHITFLVKNSSKKQGDIKDRLKTAYSALRKEFKSTFESIASDQCEIGDDEKNLLYEMKASAWYQVTYHPKWVEKSRGILGPDGEEIPASLSFAWIPVDYLARIKLRCHGKVRVEGQKPVERLAAYISERI
Protein: Ras-related GTP-binding protein (Q7ZUI2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU367014}. Lysosome {ECO:0000256|RuleBase:RU367014}.
Interaction partners:
Sequence:
MSSTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDVKIFCLVHKMDLVQEDQRDLIFKEREEDLKRLSRPLSCTCFRTSIWDETLYKAWSSIVYQLIPNVQQLECNLRNFAQIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDVFTSNTYVMVIMSDPSIPSAATLINIRNARRHFEKLERVDGPKHSLHMRMR
Protein: Tra2a protein (B1WC25)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Serine/arginine-rich splicing factor 6
- Serine/arginine-rich splicing factor 3
- Serine/arginine-rich splicing factor 1
- Serine/arginine-rich splicing factor 7
- Serine and arginine rich splicing factor 11
- Serine/arginine-rich splicing factor 10
- Serine/arginine-rich splicing factor 9
- Serine/arginine-rich splicing factor 5
- Serine and arginine rich splicing factor 4
- Embryonic polyadenylate-binding protein 2
Sequence:
MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPRRY
Protein: Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD) (Q9Y3F4)
Organism: Homo sapiens (Human)
Function: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
Subcellular location: Cytoplasm. Nucleus. Note=Localized predominantly in the cytoplasm but also found in the nucleus.
Interaction partners:
- Gem-associated protein 7
- Gem-associated protein 6
- Gem-associated protein 2
- Survival motor neuron protein
- Probable ATP-dependent RNA helicase DDX20
- Gem-associated protein 8
- Gem-associated protein 5
- Gem-associated protein 4
- Phenazine biosynthesis-like domain-containing protein
- Cold shock domain-containing protein E1
Sequence:
MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA
Protein: TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Q99JG7)
Organism: Mus musculus (Mouse)
Function: Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8NFZ5}.
Interaction partners:
- Tumor necrosis factor alpha-induced protein 3
- Mitogen-activated protein kinase kinase kinase 8
- Nuclear factor NF-kappa-B p105 subunit
- Tumor necrosis factor receptor superfamily member 1A
- Polyubiquitin-B
- Angiopoietin-1 receptor
- TNFAIP3-interacting protein 1
- Polyubiquitin-C
- TNFAIP3 interacting protein 3
Sequence:
MSSGDPRSGRQDGAPRAAAALCGLYHEAGQQLQRLKDQLAARDALIASLRTRLAALEGHTAPSLVDALLDQVERFREQLRRQEEGASETQLRQEVERLTERLEEKEREMQQLMSQPQHEQEKEVVLLRRSVAEKEKARAASDVLCRSLADETHQLRRTLAATAHMCQHLAKCLDERQCAQGDAGEKSPAELEQTSSDASGQSVIKKLQEENRLLKQKVTHVEDLNAKWQRYDASRDEYVKGLHAQLKRRQVPLEPELMKKEISRLNRQLEEKISDCAEANQELTAMRMSRDTALERVQMLEQQILAYKDDFKSERADRERAHSRIQELEEKIMSLMYQVSQRQDSREPGPCRIHTGNKTAKYLEMDALEHVTPGGWRPESRSQQMEPSAEGGHVCTAQRGQGDLQCPHCLRCFSDEQGEAFLRHLSECCQ
Protein: Protein MgtC (D0ZLQ7)
Organism: Salmonella typhimurium (strain 14028s / SGSC 2262)
Function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPISAEGEKRYILKVTCNKEDESAVRQWLLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
Protein: tRNA-dihydrouridine synthase 2, putative (Q38BB4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- glutamate--tRNA ligase
- proline--tRNA ligase
Sequence:
MSIFNGKTILAPMVRVGTVGFRVFCAAQGADIVFSEEVVASKLIRCKREVRTYTGCPCSMVEFVSYEPYKNKFKRSIAFATVARGGCNSQGEGAPVVLQLGVAEPAIGARAALLCVDDVDGIDVNMGCPKKFSVDNGMGAALMRDPARAAAILVAVDEAVNSPEKVVARRRRVPISFKTRLLDTADATAQMLLSVMEGVGPDRVHAITLHARTPDQLPDSPPHYERAAATISQLRSHKLFSKVCFVLNGSISSRGDGRRKAAQFGFDAAMIARHAMLDMSVFSKVSSEPREDPGDDREPCTDFMATPMACASWMELYRGLLRHHVIYRTPYVYTKYHLTRSVPNITALKHLMIALQRETNCYEDAARIFGLSVEEQQSMQGVSEAELLSSLPVEEQDLNEAKLLIGETTGVDGDSHVEGIHRLSKKHKGEAEMGR
Protein: exo-alpha-sialidase (EC 3.2.1.18) (Q503Z4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Arylsulfatase A.
- Galactosylceramidase b.
- UDP glycosyltransferase 8
- Galactocerebrosidase
- Alpha-galactosidase
- Beta-galactosidase.
- ST3 beta-galactoside alpha-2,3-sialyltransferase 1
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2
- N-acylneuraminate cytidylyltransferase B
- Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
Sequence:
MGSQYYPARSILFQKEPSGVTYRVPALIYIPRSSCFLAFCEERLTPADAQAHLLVMRKGTFYKNYVEWKDMEVLSTARLEGYRSMNPCPVYDEFTDTIFLFFIAVLGHTSESYQLITGKNVTRLCYVSSCDQGDTWSNATDLTRTLIGDTIKEWATFAVGPGHGTQLKSGRLIIPAYAYHIDCRNCFGKTCKTSPHSFCFYSDTHGNVWHFGQALSEPNSVECQMVSVDEEDGVNLLYCNARSISGYRVQAVSFDHGTFFQDGQLVHKLLEPRNGCHGSVIGFPAPIFQLERFKSIYNSLELSAAPRSPKNFLPPTWVVYSHPTCPNSRRDLGVYLSLLPRDPDSWSGPWIIYDGPSAYSDLAYVDLMSSDAAGVTVFACLFESGTKTAYDEISFCIFTLYELIDHLPQDQEKTTLLKRKRIWERCFIC
Protein: S-phase kinase-associated protein 2, isoform A (S-phase kinase-associated protein 2, isoform E) (Q7YZ95)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Cullin 6
- GEO01805p1
- Cullin homolog 1
- RT03845p
- LP10147p
- CG11942
- SKP1-related D
- GEO01111p1
- Supernumerary limbs, isoform B
- G2/mitotic-specific cyclin-A
Sequence:
MSSRKHRGSENMENLCPVTRKRSTNKNHVSVVGALVSTTKSSHYEHPSSPSALTFEALEEMGIGMLDSEESSSSALSAIALAVSATSDDNSNETTPCASVSRMAHQLQHTQRLSLGSTGDITLDSPAVEDSLSMSRQSAEKLQILAQAKRSSLGSEGSGNSNSPSKRLRNPLAAVTCNNQIDGTASLNFQPSTSRLAQVRQAKKPSTTNITTRIVAADSFFVFRTPAMSAHINSGINYFERLSDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDLGLRTIRPGALEQIVRRGVLVIRLAQTSIQEPAFAPYTEVFRTRLQYLDLSMASITRSSLLTLLSHCRQLKKISLENIELDDDICAEIAKNEALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDLSADAVTALVTHISPNLIRLNIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIMKFKMLEYLSVSRCYLIPATKFIELKSMPSLTYLDIFGMLSDTAMEVLEKQLPKMGINKFIHSSVSRPTVGTRRTSIWGLRTRD
Protein: Cytochrome P450 7A1 (24-hydroxycholesterol 7-alpha-hydroxylase) (EC 1.14.14.26) (CYPVII) (Cholesterol 7-alpha-hydroxylase) (Cholesterol 7-alpha-monooxygenase) (EC 1.14.14.23) (P18125)
Organism: Rattus norvegicus (Rat)
Function: A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting step in cholesterol catabolism and bile acid biosynthesis. 7-alpha hydroxylates several oxysterols, including 4beta-hydroxycholesterol and 24-hydroxycholesterol. Catalyzes the oxidation of the 7,8 double bond of 7-dehydrocholesterol and lathosterol with direct and predominant formation of the 7-keto derivatives (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:1694852}; Single-pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305|PubMed:1694852}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Cholesterol 25-hydroxylase
- 3 beta-hydroxysteroid dehydrogenase type 7
- Cholesterol 24-hydroxylase
- Cytochrome P450 2E1
- Sterol 26-hydroxylase, mitochondrial
- NADPH-dependent 3-keto-steroid reductase Hsd3b5
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4
- Bile acid receptor
- Nuclear receptor subfamily 0 group B member 2
- Steroid 17-alpha-hydroxylase/17,20 lyase
Sequence:
MMTISLIWGIAVLVSCCIWFIVGIRRRKAGEPPLENGLIPYLGCALKFGSNPLEFLRANQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPNDGNTTENINNTFTKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSNAWVTEGMYAFCYRVMFEAGYLTLFGRDISKTDTQKALILNNLDNFKQFDQVFPALVAGLPIHLFKTAHKAREKLAEGLKHKNLCVRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLAILWASQANTIPATFWSLFQMIRSPEAMKAASEEVSGALQSAGQELSSGGSAIYLDQVQLNDLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDMIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYSNGNKLKCFYMPFGSGATICPGRLFAVQEIKQFLILMLSCFELEFVESQVKCPPLDQSRAGLGILPPLHDIEFKYKLKH
Protein: UDP-galactose:fucoside alpha-3-galactosyltransferase (EC 2.4.1.37) (Alpha-GalT1) (Fucosylgalactoside 3-alpha-galactosyltransferase) (Skp1 alpha-3-galactosyltransferase) (Q54RP0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Specifically catalyzes the transfer of a galactosyl residue to the hydroxyproline-linked saccharide on Skp1 protein (fpaA/fpaB). Catalyzes the formation of a Gal-alpha-1,3-Fuc linkage, leading to Gal-Fuc-Gal-GlcNAc-HyPro143-Skp1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15123660}.
Interaction partners:
- Transcription initiation factor TFIID subunit 12
- TATA-binding protein-associated-factor
- Transcription initiation factor TFIID component TAF4 C-terminal domain-containing protein
- Transcription initiation factor TFIID subunit
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 9
- Transcriptional regulator
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 13
- Transcription initiation factor TFIID subunit 11
Sequence:
MEKKVEYIKENDKIVLMCNYGFRDMTLNLLKCFEKLSIDKSRYILYCMDDKAYQFFAEFKGIECQRFSRDDIINSSTSSTQLFHDNNTNDNKGIYSENAESYGDIGFRAICNEKPLVVLDVLKKGYNVLWTDTDIVWKRDPFIHFYQDINQENQFTNDDDIDLYVQQDDDDICAGFYFIRSNQRTIKFIQDSINFLNPCIDDQIAMRLFLKSQGINIKSKNILLSLSENDKKDKIRYRLLDKKLFPNGTNYFNLKITQRDNITPFIIHNNCIIGHRSKKDRFIEYGLWYINDDEIDINSNINNDDENNKEIKLFKNVLKNHTDIITSINSSDDGKLFTTSIDKSIKIWKFENTSGNDTDNGIFKVLKSKYIHKRGGIWSTFIFSSNNNNNNDYGFENLLTSSHDKTIQYWDNNLQVIQTFIGHTGIINQLIVIPNSSYFFTCSDDNTIRQFDLNNINFKRVFIGHNGWVSSIAINKNLNTLYSCSNDGTIRFWDINSGRCLNIIKGNQGGWIRKIIYNDNLNQLISGGNDGTIKIWSCDNLNNFNDNQYLLKINTNENSSINDLQFDSDTNLIYCAFENGSLKSFKLTSNNNNNNNNNNNNNNNTINYSLDKVYQGHLNSSINCIHISKSLNLLFSGGFDKQIKSWDL
Protein: Protein ULTRAPETALA 2 (Q8S8I2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription factor that acts as a key negative regulator of cell accumulation in shoot and floral meristems. Negatively regulates the size of the WUSCHEL (WUS)-expressing organizing center in inflorescence meristems. May act by down-regulating expression of WUS. Can compensate for mutant ULT1 protein when overexpressed.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15673576}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00185, ECO:0000269|PubMed:15673576}.
Interaction partners:
- Transcription repressor KAN1
- AGAMOUS-like 77
- Transcription factor HHO5
Sequence:
MERECGSKELFSKEELQEISGVHVGDDYVEVMCGCTSHRYGDAVARLKIFSDGELQITCQCTPACLEDKLTPAAFEKHSERETSRNWRNNVWVFIEGDKVPLSKTVLLRYYNKALKNSNVSKVIHRDEFVGCSTCGKERRFRLRSRGECRMHHDAIAEPNWKCCDYPYDKITCEEEEERGSRKVFRGCTRSPSCKGCTSCVCFGCKLCRFSDCNCQTCLDFTTNAKPI
Protein: Fumble (EC 2.7.1.33) (Q9NHN2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Phosphopantothenoylcysteine synthetase, isoform C
- Phosphopantothenoylcysteine decarboxylase
- Bifunctional coenzyme A synthase
- 4'-phosphopantetheine phosphatase
- Dynein regulatory complex subunit 4
Sequence:
MKVPTRNSKYSFNLKIFKLHNDKKPTSPSPPTSPVISAKRNSWRASWRSALGSKSKSIAMASDSSSDPIDLEAEPVFFEHSRCNSYCSSSSAFTELPHPAIQIPQGDELMSMPWFGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGNFLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNFSQPFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQFNGELAAALNDGVEHSIHTESDSASEAAQTSSTADEPPEKAPTSKHSTR
Protein: Cytoplasmic linker associated protein 1 (A0A0G2JUI5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Chromosome, centromere, kinetochore {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Golgi apparatus, trans-Golgi network {ECO:0000256|ARBA:ARBA00004601}.
Interaction partners:
- Kinesin-like protein KIF2B
- Serine/threonine-protein kinase PLK1
- CAP-Gly domain-containing linker protein 1
- Nuclear migration protein nudC
- Cyclin-dependent kinase 1
- Cell division cycle protein 20 homolog
- Dynactin subunit 1
- Microtubule-associated protein RP/EB family member 3
Sequence:
MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSSSSKAPSSSRRNVSMGTTRRLMASSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNAVSLKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGLLTLASTLGVAAAQLCSVCWILNLVTNITKKNCGPRAVFACASMHHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTASRGSTVSTKSMSTTGSLQRSRSDIDVNAAASAKSKVSSSSGSTAFSSAAALPPGSYASLDGTATKAEGRIRTRRQSSGSTTNVASTSSDSRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLAGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFTPLDRFGLGQSGRIPGSVSAMRVLSTSTDLEAAVADALLLGDARSKKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNAGVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLSKPPPPFSQPNSIPTAPSHKTLRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDIVSRDGGAASPATEGRGGSEVEGGRMALDNKTSLLNTQPPRAFPGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERITKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKVCIVLPAVACT
Protein: OTU domain-containing protein 7A (EC 3.4.19.12) (Zinc finger protein Cezanne 2) (Q8TE49)
Organism: Homo sapiens (Human)
Function: Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- CHRNA7-FAM7A fusion protein
- Zinc finger-containing ubiquitin peptidase 1
- Myotubularin-related protein 10
- Zinc finger protein 501
- Zinc finger protein 629
- Zinc finger protein 44
- Zinc finger protein 763
- Zinc finger protein 569
- Zinc finger protein 436
- Polyubiquitin-C
Sequence:
MVSSVLPNPTSAECWAALLHDPMTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDLTAALSDYEQLRQVHTANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSEDFRSFIERDLIEQATMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTGAEREALKRRWRWQQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARLAHLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDSVCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSVANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASPAEKGGGPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTSAQERFSAEQEQRRRDAATAAAAAAAAAAATAKRPPRRPETEGVPVPERASPGPPTQLVLKLKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGARDEACAPAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGTAGAAEHKSQTYTNGFGALRDGLEFADADAPTARSNGECGRGGPGPVQRRCQRENCAFYGRAETEHYCSYCYREELRRRREARGARP