wanglab/gogpt-training-data huggingface dataset:
Protein: Nucleoside transporter FUN26 (P31381)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Has broad nucleoside selectivity (uridine, adenosine and cytidine) and most likely functions to transport nucleosides across intracellular membranes.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Uridine nucleosidase
- IMP-specific 5'-nucleotidase 1
Sequence:
MSTSADTDTIKKPILAVPEPALADTHSEEISRSGEEHESENNEHSDEEGDNYSEREQSVSTEPLDTLPLRKKLKNLSYITFFAIGIGLLWPWNCILSASQYFKHDIFKDTSIWAKIFTSSMMSFSTISSMLFNIYLAKRQYKYSRRVINGLVWEIIVFTVMCFFTILHFLLPKWFNFMFIMMLVVISSMGTAMTQNGIMAIANVFGSEYSQGVMVGQAVAGVLPSLVLFALAFIENSSVSTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENWNVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRTNGTRDDNDEGEELQLKVPFEVLFAKLKYLVLSIFTTFVVTLVFPVFASATYVTGLPLSNAQYIPLIFTLWNLGDLYGRVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSSGDEEHNGSVIVDLCYMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLALGSIISYVFVFIIDFIIR
Protein: ETS-related transcription factor Elf-1 (E74-like factor 1) (Q60775)
Organism: Mus musculus (Mouse)
Function: Transcription factor that activates the LYN and BLK promoters.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MAAVVQQNDLVFEFASNGMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAAEALLNIDSPSPPVLDEKQINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQETNADSPGASSPEQRKRKKGRKTKPPRPDSPTTTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDQSLSSTTASSRNQANRSRVSSSPGIKGGAATILKPGNSKAANPKDPVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAVPEEATIASTMQEEAANSSVPSIRTIQASTQVPVVVSPGNQQLHTVTVPLTTVIASIDPSSGAGSQKFILQTIPSSQPMTVLKENVMLQSQKPGSPSIVLSPTQVQQVLTSNVQSICNGAGSVASAPSFSATTPVVTFSRSSQLVAHPPGTVITSVIKAQETKTLKQEVEKKAEDDLNEDAEKSAQQPQPYVMVLSSSNGFSSQVAVKQNELLEPNSF
Protein: ATP synthase subunit beta, chloroplastic (EC 7.1.2.2) (ATP synthase F1 sector subunit beta) (F-ATPase subunit beta) (P12085)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01347}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01347}.
Interaction partners:
- ATP synthase epsilon chain, chloroplastic
- ATP synthase subunit alpha, chloroplastic
- ATP synthase subunit b, chloroplastic
- ATP synthase subunit d
- ATP synthase subunit alpha
- ATP synthase subunit a, chloroplastic
- F-ATPase gamma subunit
- Os02g0750100 protein
- Os06g0714700 protein
- ATP synthase subunit c, chloroplastic
Sequence:
MRTNPTTSRPGVSTIEEKSTGRIDQIIGPVLDVTFPPGKLPYIYNALVVKSRDTDGKQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTSATFPIHRSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNLEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPRIVGNEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEASTKAINLEEENKLKK
Protein: GTPase-GDP dissociation stimulator BEM4 (Bud emergence protein 4) (P39011)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probably acts as a GEF (guanine nucleotide exchange factor) for the Rho family of small GTP-binding proteins (G proteins) that stimulates the dissociation of GDP to enable subsequent binding of GTP (By similarity). May also chaperone the processing and/or trafficking of small GTPases independently of GEF activity (By similarity). Involved in the control of polarized cell growth via CDC42-mediated signaling. Involved in the control of cell-wall organization via RHO1-mediated signaling. May also function via RHO2 and RHO4.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}. Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Cell division control protein 42
- GTP-binding protein RHO1
- GTPase-interacting component 2
- GTPase-interacting component 1
- Sporulation-regulated protein 28
- Cell division control protein 24
- Cell division control protein 11
- Serine/threonine-protein kinase CLA4
Sequence:
MDYEEILFGLQPILNASSIKDVPMNDVYLGSYLAVMDQLAVSLREPSNRDIVGKTGLLLNLVRVLEQALDICFHDTSISINDKIAFYEISSEVIRCIANAIIDNDDNREILLDSGGKKLLNYYIGGVLQLDEISSDKSEDSLVDKLQMRSVVLLRNFCIGNLKYTENLAPFIRGPLFVLLKTTQYSYLSSPEKVVLGSDLLNDILKVNYSNVQISDLFFLSQYIKKISSNVQNKELQAMEDGAVEAYSNTETQKFAGQGNQEYIEKEEEDDEEDVNCELLLNLSTCLETIVAKDETINFTNEEQLVLSMQKNLILSLVCLESKTFNNKLIVMRRLISCAGNISANLTNSNKREQSLCIETIKSSASSYALAAALMILCNSVASKSDAVALLKLISLSELIQVGSLLQDPLQYQGFLDLLRKLLNLENTMWLDIKDLFTLFQIMRRCHEQTKYYNNLRSLLTNLLNKTLTVLPSSKIHNSISSDPTIISFIAEHGTLTSCIAMDKLLVSKKALPKEAITSLWDSIFKFQNLGQAEQLSISDLFHITKTVGIYLKDSSVTADVNPIENILFKDYIQKLTLILETILSFKENKDKGSESCFNNGKFIAGIILNIVKNTKCLTPEEQNLEALAKSFF
Protein: Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic (AtARC6) (Q9FIG9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the plastid division machinery consisting in a binary fission accomplished by the simultaneous constriction of the FtsZ ring on the stromal side of the inner envelope membrane, and the ARC5 ring on the cytosolic side of the outer envelope membrane. Involved in the initiation of proplastid and plastid division (including chloroplasts, statoliths and leukoplasts). Promotes the assembly and/or stabilization of the plastid-dividing FtsZ ring, functioning as an antagonistic regulator of FtsZ dynamics against CDP1 and facilitating MCD1 positioning to membrane tethered FtsZ filaments to form the chloroplast Z-Ring; inhibits GDP-induced disassembly of FTSZ2 but enables ARC3 binding to FTSZ2-1. Relays plastid division site position between stroma and outer surface via interactions with the stromal FtsZ ring and the outer membrane PDV2 that recruits cytoplasmic ARC5 ring. Required for plastid equatorial positioning of PDV2 and ARC5. May contribute to gravitropism in stems and hypocotyls. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000269|PubMed:12897262, ECO:0000269|PubMed:15928083, ECO:0000269|PubMed:18812496}; Single-pass membrane protein {ECO:0000269|PubMed:12897262, ECO:0000269|PubMed:15928083, ECO:0000269|PubMed:18812496}. Note=Localized to a ring at the center of the chloroplasts (equatorial positioning) prior to and during constriction. {ECO:0000269|PubMed:18812496, ECO:0000269|PubMed:28248291}.
Interaction partners:
- Plastid division protein PDV2
- Cell division protein FtsZ homolog 2-1, chloroplastic
- Cell division protein FtsZ homolog 1, chloroplastic
- Eukaryotic translation initiation factor 3 subunit A
- Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3
- Eukaryotic translation initiation factor 3 subunit K
- Eukaryotic translation initiation factor 3 subunit E
- Dynamin-like protein ARC5
- Plastid division protein PDV1
- Eukaryotic translation initiation factor 3 subunit H
Sequence:
MEALSHVGIGLSPFQLCRLPPATTKLRRSHNTSTTICSASKWADRLLSDFNFTSDSSSSSFATATTTATLVSPPPSIDRPERHVPIPIDFYQVLGAQTHFLTDGIRRAFEARVSKPPQFGFSDDALISRRQILQAACETLSNPRSRREYNEGLLDDEEATVITDVPWDKVPGALCVLQEGGETEIVLRVGEALLKERLPKSFKQDVVLVMALAFLDVSRDAMALDPPDFITGYEFVEEALKLLQEEGASSLAPDLRAQIDETLEEITPRYVLELLGLPLGDDYAAKRLNGLSGVRNILWSVGGGGASALVGGLTREKFMNEAFLRMTAAEQVDLFVATPSNIPAESFEVYEVALALVAQAFIGKKPHLLQDADKQFQQLQQAKVMAMEIPAMLYDTRNNWEIDFGLERGLCALLIGKVDECRMWLGLDSEDSQYRNPAIVEFVLENSNRDDNDDLPGLCKLLETWLAGVVFPRFRDTKDKKFKLGDYYDDPMVLSYLERVEVVQGSPLAAAAAMARIGAEHVKASAMQALQKVFPSRYTDRNSAEPKDVQETVFSVDPVGNNVGRDGEPGVFIAEAVRPSENFETNDYAIRAGVSESSVDETTVEMSVADMLKEASVKILAAGVAIGLISLFSQKYFLKSSSSFQRKDMVSSMESDVATIGSVRADDSEALPRMDARTAENIVSKWQKIKSLAFGPDHRIEMLPEVLDGRMLKIWTDRAAETAQLGLVYDYTLLKLSVDSVTVSADGTRALVEATLEESACLSDLVHPENNATDVRTYTTRYEVFWSKSGWKITEGSVLAS
Protein: Uncharacterized protein YibN (P0AG27)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Glutaredoxin 3
- Protein-export protein SecB
- Uncharacterized protein YicN
- Glycerol-3-phosphate dehydrogenase [NAD
Sequence:
MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGEATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDGSGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK
Protein: Unhealthy ribosome biogenesis protein 2 homolog (B0V0U6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MAAIYSGIQLKLKNTRTPWPDKLKLARFAWISTQCLLPNKEQVLFDWTNHALTCFYNKKVEMPPEVVEGLWTYLDDILHSRKLHNVLSQGKTISLRLTVAQFIIKESSKLPSLTRVLTVPGLEALTVLLRQGKAQISNPHQVIVVLGALQFVPLDSHCMEDYHSAFEAVHEALFAIIHCYPQVMLKASPTFLNCFYRLVSSVMHEGKQRSDTDRASEKDRESLLKCARLVERMYTHVASAAEDFTVLSSFMVAQYVSELQRVTLQPEIKAHLTEGIYCILDHCVEQDIKFLNTTLQMGVKEVFNELYSSYTHYHKSQRQGEEKYTV
Protein: CBL-interacting serine/threonine-protein kinase 12 (EC 2.7.11.1) (SNF1-related kinase 3.9) (SOS2-like protein kinase PKS8) (Q9SN43)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
Interaction partners:
- Calcineurin B-like protein 2
- Calcineurin B-like protein 1
- Calcineurin B-like protein 3
- Ethylene-responsive transcription factor ERF037
- Calcineurin B-like protein 9
- Calcineurin B-like protein 4
Sequence:
MAEKITRETSLPKERSSPQALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPRWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFKKGFKHIKFYVEDDKLCNVVDDDELESDSVESDRDSAASESEIEYLEPRRRVGGLPRPASLNAFDIISFSQGFDLSGLFDDDGEGSRFVSGAPVSKIISKLEEIAKVVSFTVRKKDCRVSLEGSRQGVKGPLTIAAEIFELTPSLVVVEVKKKGGDKTEYEDFCNNELKPKLQNLTADDVVAEPVAVSAVDETAIPNSPTISFLPSDTE
Protein: Calcium-dependent protein kinase 31 (EC 2.7.11.1) (Q9S9V0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Interaction partners:
- Aquaporin NIP1-1
Sequence:
MGCYSSKNLKQSKRTILEKPFVDIGKVYILGDELGQGQFGITRKCVEKTSGKTYACKTILKTNLKSREDEEAVKREIRIMKHLSGEPNIVEFKKAYEDRDSVHIVMEYCGGGELFKKIEALSKDGKSYSEKEAVEIIRPIVNVVKNCHYMGVMLRDLKPENFLLSSTDKNATVKAIDFGCSVFIEEGEVHRKFAGSAYYIAPEVLQGKYGKEADIWSAGIILYILLCGKPPFVTEPEAQMFSEIKSAKIDVDSESWKFIDVKAKHLVNRMLNRNPKERISAAEVLGHPWMKDGEASDKPIDGVVLSRLKQFRDMNKLKKVALKVIAANLSEEEIKGLKTLFTNIDTDKSGTITLEELKTGLTRLGSNLSKTEVEQLMEAADVDGNGTIDIDEFISATMHRYRLDRDDHVYQAFQHFDKDNDGHITKEELEMAMKEHGVGDEVSIKQIITEVDTDNDGKINFEEFRTMMRSGSSLQPQRELLPIK
Protein: Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw) (Q61371)
Organism: Mus musculus (Mouse)
Function: Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:20230748, ECO:0000269|PubMed:23386061}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:19253336, ECO:0000269|PubMed:20230748}. Cell projection, cilium {ECO:0000250|UniProtKB:Q13099}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q13099}. Cytoplasm {ECO:0000269|PubMed:27682589}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:27682589, ECO:0000269|PubMed:34124066}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:34124066}. Note=Colocalizes with ENTR1 and gamma-tubulin at the basal body of primary cilia (By similarity). Colocalizes with ENTR1 and pericentrin at the centrosome (By similarity). In sperm cells, localizes to the manchette, head-tail coupling apparatus and flagellum (PubMed:34124066). {ECO:0000250|UniProtKB:Q13099, ECO:0000269|PubMed:34124066}.
Interaction partners:
- Intraflagellar transport protein 52 homolog
- Intraflagellar transport protein 20 homolog
- Intraflagellar transport protein 74 homolog
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 57 homolog
- Intraflagellar transport protein 172 homolog
- Intraflagellar transport protein 27 homolog
- Intraflagellar transport protein 80 homolog
- Intraflagellar transport protein 56
Sequence:
MENVHLAPETDEDDLYSGFNDYNPAYDTEELENDTGFQQAVRTSHGRRPPVTAKIPSTAVSRPIATGYGSKTSLTSSMGRPMTGTIQDGVARPMTAVRAAGFSKAALRGSAFDPLGQSRGPAPPLEAKNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTSPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGITFIKTGQYSDAINSFEHIMSMAPSLKAGFNLILSCFAIGDREKMKKAFQKLIAVPLEIDEDDKYISPSDDPHTNLLIEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIEASFAVGYNWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVDTLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYKKLNRLDEALDSFLKLHAILRNSAQVLCQIANIYELMEDPNQAIEWLMQLISVVPTDSQALSKLGELYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKEIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEMREQRIKSGRDSSGGSRSKREGSAGSDSGQNNSASSKSERLSAKLRALPGTDEPYESSGNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE
Protein: Protein BASIC PENTACYSTEINE6 (AtBPC6) (GAGA-binding transcriptional activator BBR/BPC6) (Q8L999)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
Subcellular location: Nucleus {ECO:0000269|PubMed:14731261}. Nucleus, nucleolus {ECO:0000269|PubMed:14731261}.
Interaction partners:
- Chromo domain-containing protein LHP1
- Histone-lysine N-methyltransferase EZA1
Sequence:
MDDGGHRENGRHKAAVQGQWLMQHQPSMKQVMSIIAERDAAIQERNLAISEKKAAVAERDMAFLQRDTAIAERNNAIMERDSALTALQYRENSMVTAPAANMSACPPGCQISRGVKHLHHPHMHHHHQQHHIPQLTENAYETREMEPNDGLPTSPPAGSTLESAKPKRGKRVNPKATTQTAANKRGPKNQRKVKKESEDDLNKIMFVKTTHDYTDEDSSKHILIGSKSDWKSQEMVGLNQVVYDETTMPPPVCSCTGVLRQCYKWGNGGWQSSCCTTTLSMYPLPALPNKRHARVGGRKMSGSAFNKLLSRLAAEGHHDLSNPVDLKDHWAKHGTNRYITIK
Protein: C2H2-type domain-containing protein (A0A131MCL4)
Organism: Caenorhabditis elegans
Interaction partners:
- COG-1A
- Zinc finger protein lsy-2
- Formin-homology and zinc finger domains protein 1
- T-box protein 37
- LIM/homeobox protein lim-6
Sequence:
MMANAVDMQQLLMSMDPSSANQFNMMNKGGACVMATSGGSASPTSSSGAPSSSSIMAETDEKDMFMPSQLIQNGLANNQLMSMILQQQSNQADSNIADAGHNNSGAEKNIIELLMSGNADLMKFATQFAQQAKSVDQEPEEQRESSPSPPPAVSLNSTLASMVFPTTSTATECSAASTTSSVDSAPSTVIVNGHSNSQSNTDDDDVTQQPSAKKQRTGDETPLTPTSNNQLMQSLLAQMGLSNPLHQQNQKQMKDESMMFSGLFPQGLAGIPLMFQSPLHQQFAGMQDFEPLSALSTPNKGSGVKRQYSSNNKNFCDICNKEVCNKYFLRTHMLKMHGIVIDENKTVIANIDTSIKEREGELTFRCDTCRTMFKTRNQLRQHRQDVHGVLPLSTPRNNPNKSSVPTTPNGANNNSGPNSASMSEEKCALCDKRVSPSMMMLHMAQDHFGAAAANGDLNQMMAILGQRNQSTEEKMSSNLLECTDCSYKTRDPKNLDLHMERHIKMSEAKGRGDEDEDVALQLTTEAALQMVVQNQNQYDGDSTAAALNLTFKNDGTKKEIEEEKATGNHERNSHTSGSISPSGSIPEGFGKNIGEKAFPTQSFLIKCNDDSGEFLTEFLAQLPVRSVIDGPRQLVFNLHPAPPTTS
Protein: Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII) (Q9UNF0)
Organism: Homo sapiens (Human)
Function: Regulates the morphogenesis and endocytosis of caveolae (By similarity). Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9WVE8}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9WVE8}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9WVE8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9WVE8}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9WVE8}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:Q9WVE8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9WVE8}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9WVE8}. Early endosome {ECO:0000250|UniProtKB:Q9WVE8}. Recycling endosome membrane {ECO:0000250}. Cell membrane {ECO:0000250|UniProtKB:Q9WVE8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9WVE8}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9WVE8}. Cell projection {ECO:0000269|PubMed:31242077}. Membrane, caveola {ECO:0000269|PubMed:22323287}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q9WVE8}. Note=Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1. {ECO:0000250|UniProtKB:Q9WVE8}.
Interaction partners:
- Actin nucleation-promoting factor WASL
- Protein kinase C and casein kinase substrate in neurons protein 3
- Protein kinase C and casein kinase substrate in neurons protein 1
- EH domain-containing protein 1
- Protein cordon-bleu
- Dynamin-2
- MICAL-like protein 1
- EH domain-containing protein 2
- Cordon-bleu protein-like 1
- EH domain-containing protein 3
Sequence:
MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ
Protein: Branched chain amino acid ABC transporter ATP binding protein (Q9HUQ3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable permease of ABC branched-chain amino acid transporter
- Branched chain amino acid ABC transporter membrane protein
- High-affinity branched-chain amino acid transport system permease protein BraE
- Amino acid binding protein
- High-affinity branched-chain amino acid transport system permease protein BraD
- High-affinity branched-chain amino acid transport ATP-binding protein
- Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein
- High-affinity branched-chain amino acid transport ATP-binding protein BraF
- Aliphatic amidase expression-regulating protein
- Probable permease of ABC transporter
Sequence:
MSDKILSVEHLMMHFGGIKALNDVNLDVERGSITALIGPNGAGKTTVFNCLTGFYKATGGNILLNTQGRTTDVIQVLGEPFQLDDFVKPPQLGSRLYYKMFGGTHLVNRAGLARTFQNIRLFKDMSVVENLLVAQHMFVNRNLLAGILNTPGYRRAESEALDHAFYWLEVVDLVDCANRLAGEMSYGQQRRLEIARAMCTRPELICLDEPAAGLNPAETHALSNIVRYLRDHHGITVLLIEHDMGMVMNISDHIIVLDHGDVIARGNPEQIRHDEKVIAAYLGADEEELS
Protein: P2Y purinoceptor 11 (P2Y11) (Q96G91)
Organism: Homo sapiens (Human)
Function: Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Suppressor of SWI4 1 homolog
- P2Y purinoceptor 13
- P2X purinoceptor 1
- Eukaryotic translation initiation factor 3 subunit G
- RRP15-like protein
- Ribosome biogenesis protein BOP1
- Surfeit locus protein 6
- Ribosomal L1 domain-containing protein 1
- Ribosome production factor 1
- Pescadillo homolog
Sequence:
MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ
Protein: Golgi reassembly-stacking protein 1 (Golgi peripheral membrane protein p65) (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Q91X51)
Organism: Mus musculus (Mouse)
Function: Key structural protein of the Golgi apparatus. The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon. Acting in concert with GORASP2/GRASP55, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks. However, other studies suggest that GORASP1 plays an important role in assembly and membrane stacking of the cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis (By similarity). Caspase-mediated cleavage of GORASP1 is required for fragmentation of the Golgi during apoptosis (By similarity). Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes (By similarity). Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (By similarity).
Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:O35254}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35254}; Cytoplasmic side {ECO:0000250|UniProtKB:O35254}.
Interaction partners:
- Golgin subfamily A member 2
- Golgin-45
- Serine/threonine-protein kinase PLK1
- General vesicular transport factor p115
- Golgin B1
- Syntaxin-5
- WD40 repeat-containing protein SMU1
- Golgi SNAP receptor complex member 1
- SEC24 homolog B, COPII coat complex component)
- GRIP and coiled-coil domain-containing protein 2
Sequence:
MGLGASSEQPAGGEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLCPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPSSQHKKPPGATPPGTPATTSQLTAFPLGAPPPWPIPQDSSGPELGSRQSDFMEALPQVPGSFMEGQLLGPGSPSHGAADCGGCLRAMEIPLQPPPPVQRVMDPGFLDVSGMSLLDSSNISVCPSLSSSTVLTSTAVSVSGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGAQAQADHLPRLTLPDGLTSAASPEEGLSAELLEAQTEEPADTASLDCRAETEGRASQAQATPDPEPGL
Protein: Ribosomal protein uL16 3-hydroxylase (EC 1.14.11.47) (Ribosomal oxygenase RoxA) (ROX) (P27431)
Organism: Escherichia coli (strain K12)
Function: Growth-regulating oxygenase that catalyzes the hydroxylation of 50S ribosomal protein L16 on 'Arg-81'.
Interaction partners:
- Large ribosomal subunit protein uL16
- Disulfide bond formation protein B
- Ribosomal protein S12 methylthiotransferase accessory factor YcaO
Sequence:
MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLLQVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALDALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG
Protein: FEMCOAT (Q9GTX9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLRFGQQLMLLAMACFALQMAHGWLLKLPKLEAKLEAKEAKDEAMLDWFEGKKQTELLKKLDFLNLFTEKEEAKLEKKENEWEKFKQWWDEKKEKELAFFEAKKEKELAFFEGKLSKKSGKKSKSKKTTVKPCYGYQEQDQDTAKYYSAEATEAEYEQSEEVTEKPSRKTYERKSYDRRTYSLPTLRCEDDSAERTRYFT
Protein: Diaminopimelate decarboxylase (EC 4.1.1.20) (E0SIF1)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Interaction partners:
- Putative AcsD
- Diaminopimelate epimerase
- Diaminopimelate decarboxylase
- Diaminopimelate decarboxylase
- UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
- Achromobactin siderophore NIS synthase
- Achromobactin siderophore NIS synthase
- Lysine 2,3-aminomutase
Sequence:
MVNLPQHVHDVIVLLQQQHTDPLAAFVYDLTALRQHVSEVMAALPPGVELYYAIKANSEKPILDAIAPLVHGFEISSGGEIARVAGCGTRKPFVFSGPGKLDSDFDLALEQGVEAVHVESRHEIARLQQRARQHGVVQPVFIRVNPELASSLTSKLAMAGTPTPFGMDEADLADAVRDVDNASHLQLKGFHVHAMSHQMVVARHQQLLDLYLTRWPQWKALSAHPQHITHLNVGGGIGVPYLTPERFDWPALCDYLRTRLAQQPDAPIVRFEPGRFISAYCGYYAIEVLDKKRSHGKHFLVCRGGTHQFRLPVAQGHDHPVIHLPLTSAPTTGETRDWTVVGQLCTPKDVLSRDQRLTDVNIGDLLVLPLAGAYGYNISHADFLCHPRPGQYFTTEDGMTTDAAGVVSRVE