wanglab/gogpt-training-data huggingface dataset:
Protein: Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A) (Q9VR07)
Organism: Drosophila melanogaster (Fruit fly)
Function: Plays a role in neuronal membrane excitation, important for normal response properties of the photoreceptor. Able to control excitability from either neurons or glia cells. Ine negatively regulates neuronal sodium channels. Controls neurotransmitter-mediated signaling pathways associated with the structure of the larval peripheral nerve, ine and eag control perineurial glial growth through partially redundant pathways. Isoform A and isoform B are both functional, although isoform A functions with greater efficiency. Has a role in osmolyte transport within the Malpighian tubule and hindgut.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Carcinine transporter
Sequence:
MAENKDVSQVLNTTPDQVVINRAPPTGLAPLRHSQLSDSGAESCYEGDEQARLIRSSSSRAHKFIIIPATPGTPPGSGAVAGPLPFRQTSSTTSLAAMAAALHKQSPLRHTSVRTRPSSEVLQPGQVLANQPTAAVSTSTVTFTIDDCNEEGDAIPAAASVPAPVTMPAISPTPATLTCTTTTTMAGDSVAVSPLSMELKSRLGSHHSSMRSVVSGYLPGLSDSSGNLVGGVSMATSGLQAPNPLYMQPQASLSGSSYHFHELAGNQIYSDVTSVRSLASIGIGSTDGRKLVIRRVPTTANELFDMVNPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQEQFMLAQEMATVYKPTNPHLLNLGQKCGYNAMQASPSHAEAGGPCGQ
Protein: U4/U6 small nuclear ribonucleoprotein PRP3 (Pre-mRNA-splicing factor 3) (Q03338)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
Subcellular location: Nucleus.
Interaction partners:
- Pre-mRNA-processing factor 31
- LSM complex subunit LSM2
- Small nuclear ribonucleoprotein Sm D3
- LSM complex subunit LSM4
- Pre-mRNA-splicing factor SNU114
- 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component
- LSM2-LSM8 complex subunit LSM8
- 13 kDa ribonucleoprotein-associated protein
- U4/U6 small nuclear ribonucleoprotein PRP4
- Pre-mRNA-splicing factor 8
Sequence:
MPPRNTYEKGNPKRQNSPYYKPSFLRREETTNDEEKFQGHGLKTELHSALKSSNLNLIRRTYQTGENPYLSDPHDRGSSSRFNRRYERGLKFYQKGEISKRIAQERTLQKQQEEEELKRKLKQEEDEKDKRKLIESGDLPNLELHEDKFLLDLSKFKIYYDNNHGYEWWDTAYLDEKGELMEKYDMNGTSPAEEKLAEDIDEVDDDDDDEHPSIRYVAHPLPEKINEAKVSIKAYLTQHERKRLRRNRRKMAREAREIKIKLGLLPKPEPKVKLSNMMSVFENDQNITDPTAWEKVVKDQVDLRKRKHLEENERRHEDAIKRRKEAVNMNVEKPTVYHCKVFQFKNLQNPKIRFKLKMNSKELSLKGLCLRIRDDGPGIIIVVGNEKSCKFYENLVMKRIKWNEDFELHTNTGDIKMDMHNNSISKTWEGYLQDCKFKGWFMKVCNDQDSLLRTLGQFDSEHFYSPVQT
Protein: Breast cancer anti-estrogen resistance 1 (Q6P5Z4)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGPGSGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPNPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLAAA
Protein: Cell differentiation protein, putative (Q57UT4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- NOT1
- poly
- NOT2/NOT3/NOT5 C-terminal domain-containing protein
- Uncharacterized protein
- ATP-dependent DEAD/H RNA helicase, putative
- Endonuclease/exonuclease/phosphatase domain-containing protein
- Endonuclease/exonuclease/phosphatase, putative
- CCR4-NOT transcription complex subunit 11
- CCR4-NOT transcription complex subunit 10
- ATP-dependent DEAD/H RNA helicase, putative
Sequence:
MHQTQAYLPYGFYQPQQAAAKQQPPVSEDMRRMFQYLEGLYKPETRENSILELAKDRESYHHLGPALWYGVGIMSVLLQEIISVYPLLSTPHLLAKGMANRVSSVLTLLQAVAFHESTRRMFLDSQMCLFLYPFLRGMNEGTEGLRLTSLGVIGALVKTDDHDVVQYLLNTEIFPLCLNIMESGTEFSKTLATFIVQRLLNSEGGLKYVCLTPERFTAVATVLGKLVESKDCSTRLLRYIIRCYLRLSENQRGREALSRCLPQALRNATYKQALESNTGLVRNLLQLLVNIGDAGATKLHESLLAGGKPQGGDASA
Protein: Voltage-dependent L-type calcium channel subunit alpha (Q6QRQ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003808}.
Interaction partners:
Sequence:
MSANGPAPPAATPAAPPAAAVPVPSVVPVGSLAQKKRAQYAKSKKQGSSANTRPQRALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHASCYFQGTDILEDEPAPCAVNGHGRTCPINGTLCKEGWQGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGLELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEEEESKRNRVTLASLMEKKKKGFGWFSQSSDTHASMPASETESMNTENEKGEDEKATCCGPTCQKISKSKFSRRWRRWNRLCRRNCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLAMFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVEFEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTDDTKKPDEIDEIEDEAKAGEEDEKDNAEEDEEEPDVPAGPRPKISELVKKEKITPIPEGSAFFIFSNTNPVRVACHKLINHHIFTNLILVFIMLSSASLAAEDPIRNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKEGDVNQPIIQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLILLNTICLAVQHYGQSELFNYVMDILNMVFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDHTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESDYNPGEEMTCGSSFAIIYFITFYMLCAFLIINLFVAVIMDNFDYLTRDWSXLGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTAXKIKTEGNLEQANEELRAVIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEEGLVGVHPAQNNTAIALQAGLRTLHDIGPEIRRAISCDLQDDELVDFIPEEDEEIYRRNGGLFGNHINHINGDPRRSSGHQTNATQRPLQVQPPPHYVHMEQPVGRLGRANAMAQQNHHRHHHHHHHHHHHNNSYNKSPKSTNINLNNANVSSXPNGGHNRYYEHAPANGYPGSYYGEYDKPRTPHGQRRRYYETYIRSQGSDRRRPTIRREEEYEEDRYSGEYYSGEEFYEDDSMLSGDRYPNSDQEYETPRGYHHPDSYYEDDEQPLYHDSHRSPKRRLLPPTPQGNRRPSFNFECLRRQSSQDDLPHQRTALPLHLMQHQVMAVAGLDSSRAHRLSPTRSTRSWASPPPTPASKDRTPYYTPLIRVDRPLRDSASSSHSSIRKSSWYTDDPEYQQRNXSPVHLQVPPEYRNQYLQKRGSATSLVEAVLISEGLGRYAKDPKFVAAXKHEIADACEMTIDEMESAASHXLNGGITPVVNGVNVFPILGHREYELQDVSASYSDEEPEPEPRPRYEEDLADEMICITTL
Protein: Glycine receptor subunit alpha-4 (Q61603)
Organism: Mus musculus (Mouse)
Function: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (Probable).
Subcellular location: Postsynaptic cell membrane {ECO:0000305|PubMed:17154252}; Multi-pass membrane protein {ECO:0000305}. Synapse {ECO:0000269|PubMed:17154252, ECO:0000269|PubMed:22592841}. Perikaryon {ECO:0000269|PubMed:17154252}. Cell projection, dendrite {ECO:0000269|PubMed:17154252}. Cell membrane {ECO:0000269|PubMed:10762330, ECO:0000269|PubMed:22592841, ECO:0000305|PubMed:17154252}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MTTLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRESRFYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTPLLKEGETMRKLYVDRAKRIDTISRAVFPFTFLVFNIFYWVVYKVLRSEDIHQAL
Protein: Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (LIM domain only protein 5) (LMO-5) (Smooth muscle cell LIM protein) (SmLIM) (Q16527)
Organism: Homo sapiens (Human)
Function: Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
Sequence:
MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ
Protein: GH19970p (Sodium/solute co-transporter-like 5A11) (Q9VLR8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- KCNQ potassium channel, isoform F
Sequence:
MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHRFLPKECFSGRNLHAQAHKNLLNVS
Protein: Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (A0A024RCN6)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPALEQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISLQQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVADEATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARELGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALFQKML
Protein: Aspartate beta-hydroxylase domain-containing protein 2 (EC 1.14.11.-) (Q6ICH7)
Organism: Homo sapiens (Human)
Function: May function as 2-oxoglutarate-dependent dioxygenase.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MVWAPLGPPRTDCLTLLHTPSKDSPKMSLEWLVAWSWSLDGLRDCIATGIQSVRDCDTTAVITVACLLVLFVWYCYHVGREQPRPYVSVNSLMQAADANGLQNGYVYCQSPECVRCTHNEGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTTPYFSRDAQKHDVEVLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLFDDSFLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR
Protein: Protocadherin 11 X-linked (B1AZR7)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MDLLSGTYIFAVLLACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESVPNATLIYELVRRSIDAPANQNTETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQPPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVTIEEAKPDDGENERNSVTLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKAPVSVHIRPTMKEVVRSHTPMKEATTVEIWTHPHPQSQRRVTFHLPEGSQESISDGGLGDHDAGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESTAEITVQPTVEEASDTCTQECLILGHSDSCWMPATLTNPSPSQIKTSAICHSPPRPRLSVRRYSPPVTQTVTICHSPPVTQAIALCHSPPPVQVTVPRHSPPPAQASAVSYSPTLVQAVVIHHSPPLPQAATHHRTQAQPPMGLQQGWVQGAGADGLYPIDQGVQGSTRAQFYTMAERFHPDDDSIKVIPLTTFTSGQQARSSRGDSPIIEEHPL
Protein: MFS antiporter QDR2 (Q59YT1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence. No substrate for transport has been identified yet, but plays an important role in the growth in the host.
Subcellular location: Cell membrane {ECO:0000269|PubMed:24621232}; Multi-pass membrane protein {ECO:0000269|PubMed:24621232}. Note=Preferentially localizes to membrane rafts. {ECO:0000269|PubMed:24621232, ECO:0000303|PubMed:19055746}.
Interaction partners:
Sequence:
MLSTTQSVTEPTEVTSKKVEDIEKENDEETPYSIFTSYDRLVLIVILSLIGFWSTISSPIYFPALPTLTSYFHTSSSIMNISVVAYLIFQGIAPTISSNLADTFGRRPVILASIIVFCASCVAISQTNVYWLLAVLRCIQAAGIAAVISISSGVAGDVCTRANRGSMVGAVAGLQLVGNGIGGLVGAALISSFNSWRSIFIFLTIGGGVTFILAIFILPETSRKLVGNGSVVPKNILNKSPYIYLPHFKKRMNNDITTIVPATRFDLLGPLKIFFQKNVFCTLLPVGIHFAAWTMVLTSLSTELESRYHYSVMHVGLIYLPQGIACIAGSLVVGKSLDWYYRYRKTIYDQEVECLPLDERPQFNIVATRLTLSVVPALLMIIGLVIFGWCIQYKRHIISIIISTILVSFSASVFIAICTTMLVDLYPNNGSGSTSCLNLMRCWLAALGAGVLDSMINAMNVGGTYTVVAGFCILFDLALIYVLHNAKKKFSNSGPTTTKSPPKQ
Protein: Cyclin-I (Q9Z2V9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MKFPGPLENQRLSSLLERAISREAQMWKVNVPKIPTNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLNCIAISCFFLAAKTVEEDEKIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSARPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFKGSMLALAMVSLEMEKLIPDWLPLTIELLQKAQMDSSQLIHCRELVAYHLSALQSALPLNSVYVYRPLKHTLVTCDKGAFKLHPSSVSGPDFSKDNSKPEVPVRGPAAFHLHLPAASGCKQTSAKRKVEEMEVDDFYDGIKRLYNEDNGPENVGSVCGTDLSRQEGHASPCPPLQPVSVM
Protein: B2 bradykinin receptor (B2R) (BK-2 receptor) (P32299)
Organism: Mus musculus (Mouse)
Function: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P30411}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Kininogen-1
- Angiotensinogen
- Guanine nucleotide-binding protein G
- B1 bradykinin receptor
- Endothelin-1
- Prothrombin
- Guanine nucleotide-binding protein subunit alpha-11
- HMW kininogen-II
- Guanine nucleotide-binding protein subunit alpha-14
- Guanine nucleotide-binding protein G
Sequence:
MPCSWKLLGFLSVHEPMPTAASFGIEMFNVTTQVLGSALNGTLSKDNCPDTEWWSWLNAIQAPFLWVLFLLAALENLFVLSVFFLHKNSCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWVFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMREYSEEGHNVTACVIVYPSRSWEVFTNVLLNLVGFLLPLSVITFCTVRILQVLRNNEMKKFKEVQTERKATVLVLAVLGLFVLCWVPFQISTFLDTLLRLGVLSGCWDEHAVDVITQISSYVAYSNSGLNPLVYVIVGKRFRKKSREVYRVLCQKGGCMGEPVQMENSMGTLRTSISVERQIHKLQDWAGKKQ
Protein: Conserved flagellar protein F (Q4J9K8)
Organism: Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Interaction partners:
- Flagellar protein FlaG
- Flagella-related protein J
- Archaeal flagellar ATP-binding protein FlaH
- Archaeal flagellar ATPase motor FlaI
- Flagellin
- Archaeal flagellar motor scaffold protein FlaX
Sequence:
MGVSQTLAFILITFIGVSFGIVLLSAYFKSQQILNQAQELNHELELEQLETKITVSSVSLTGSTLNVVLENNGSTNLYDFQGFSVIVQYYANISNISTFNLSLYNYTKNSNPSPYYWTINTPLLAPGSQATLTIILPYPPYPNTQATVVIVTNYGPSVIWRGSL
Protein: Putative RING zinc finger (RING/U-box superfamily protein) (Q8GS41)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Small ubiquitin-related modifier 1
- Uncharacterized protein At5g02240
- Ubiquitin-like superfamily protein
- Zinc ion binding protein
- Probable ubiquitin-like-specific protease 2B
- Cysteine proteinases superfamily protein
- Ubiquitin-ribosomal protein eL40z fusion protein
- Ubiquitin-ribosomal protein eL40y fusion protein
- Probable ubiquitin-like-specific protease 2A
- Ubiquitin-ribosomal protein eS31z fusion protein
Sequence:
MNTSEVRVPRGNRRRKAVIDLNAVPVDQEGTSASVRTLTVPITPSQPAPTMIDVDAIEDDVIESSASAFAEAKSKSRNARRRPLMVDVESGGTTRFPANISNKRRRIPSSESVIDCEHASVNDEVNMSSRVSRSKAPAPPPEEPKFTCPICMCPFTEEMSTKCGHIFCKGCIKMAISRQGKCPTCRKKVTAKELIRVFLPTTR
Protein: Septin homolog spn2 (Q09116)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells. Involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4-phosphate.
Subcellular location: Cytoplasm, cell cortex. Forespore membrane; Peripheral membrane protein. Note=Localizes to the medial ring at the cell cortex of dividing cells. The sporulation-specific septin complex associates to the forespore membrane and forms partial or complete ring-like structures that curl around each haploid nucleus.
Interaction partners:
- Septin homolog spn4
- Septin homolog spn1
- Septin homolog spn5
- Septin homolog spn7
- Septin homolog spn6
- Septin homolog spn3
- Septin ring organizing protein mid2
Sequence:
MEVPSAVTLNNYVGFDSITSQINRKLIRRGFQFNVMVVGPSGSGKSTLINTLFSAHLMDSKGRLDYQAPYRQTTEIHVTSQVVRENRVQLQLNLIDTPGYGDQINNDKCWEPIIKYIRDQHSSYLRRELNSHREKRLQDTRVHCCLFFIRPTGHSLRPIDIAVLKRLTEVVNVVPVIAKSDSLTLEERAAFKQQIREEFVKHDINLYPYDSDDADEEEINLNAAVRNLIPFAVVGSEKAIIVDGRPIRGRQNRWGVVNVDDENHCEFVFLRNFLMRTHLQDLIETTSYYHYEKFRFKQLSSLKEQSSLATRMGSPAPVYPSEPHLHTATAQ
Protein: 26S proteasome non-ATPase regulatory subunit 10 (Gankyrin) (Proteasome 26S subunit, non-ATPase 10) (Proteasome 26S subunit, non-ATPase, 10) (Q6TGV5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Proteasome 26S subunit, ATPase 3
- 26S proteasome regulatory subunit 10B
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome regulatory subunit 6B
- 26S proteasome regulatory subunit 7
- 26S proteasome regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 1
- 26S proteasome non-ATPase regulatory subunit 12
- Proteasome 26S subunit, non-ATPase 6.
- Proteasome 26S subunit, non-ATPase 14.
Sequence:
MEARVSNVEVCNLAYGGKFEELKKCVLSDNSLAAKTDQDSRTALHWACSAGHVNIAQFLLDLGVEVDLKDDACWTPLHIAASAGREEIVRSLISKGAQLNSVNQNGCTPLHYAASKNLYEIAQILLENGADPNATDKLQSTPLHRASAKGNYRLIQLLLKESASTNIQDSEGNTPLHLACDEERAEAAKLLVEHGASIYIENKEKMTPLQVAKGGLGSVLKRIVEG
Protein: Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)] (P01137)
Organism: Homo sapiens (Human)
Function: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
Subcellular location: [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17827158}.; SUBCELLULAR LOCATION: [Transforming growth factor beta-1]: Secreted {ECO:0000269|PubMed:17827158, ECO:0000269|PubMed:29483653}.
Interaction partners:
- Decorin
- TGF-beta receptor type-1
- Latent-transforming growth factor beta-binding protein 1
- TGF-beta receptor type-2
- Endoglin
- Transforming growth factor beta receptor type 3
- Latent-transforming growth factor beta-binding protein 4
- Latent-transforming growth factor beta-binding protein 3
- Transforming growth factor beta activator LRRC32
- Integrin alpha-V
Sequence:
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
Protein: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (Complex I-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) (F7ELE5)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
TSRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR
Protein: ACP53C14C (Q6GUV3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKSKQVFYIAFSLLLLGSLLPNEVESLRVDLNKLAECTESGLKVATTLLVRAIPCVKKLAKCADFRAIKTKDLDITALTLLGYQYLQTVVNNQRCLLISLKEGYDAVSPHLDKLISGKCLPGLS
Protein: Rap-GAP domain-containing protein (H2L055)
Organism: Caenorhabditis elegans
Interaction partners:
- Ras-related protein Rap-1
- cGMP-dependent protein kinase egl-4
- cAMP-dependent protein kinase catalytic subunit
Sequence:
MLHFIDSSESEDDLDELPRHLPPVIRRLAPLRHATSQYNLRSTGSTSSDSSTASENDKCSDFSSLKSRRASCIELNKEDEFKVMAADKLLMAMENMKHATSSQAIRWRTTSTESLPGIIKSNRRHSKGPLELIQGLMAKKAAVGRPAKFKNLGVVGPPTLISSTVSLHEISGFTHNPTSGHQNEQTHQKTNGSAVHNQLTRNIMNEVLTKVGPYPQIVLPSNGFWMDGVNQQHHMDDQVNNMNVNSCARFKLETDETSHCYRRHFFGREHHDFFANDPIVGPLVLSVRTEVISSCDHFRIILRTRKGTIHEIVSATALADRPSASRMAKLLCEEITTEQFSPVAFPGGSELIVQYDEHVLTNTYKFGVIYQKGGQTTEEQLFGNPHGSPAFDEFLSMIGDSVQLNGFQKYRGGLDTAHNQTGHQSVFSEFKNREIMFHVSTMLPYTIGDAQQLQRKRHIGNDIVAIIFQEANTPFAPDMIASNFLHAYVVVQPIDALTDRVRYRVSVAARDDVPFFGPTLPTPSIFKRGQDFRNFLLTKLINAENAAYKSSKFAKLAERTRSSLLDGLHATLRERAEFYATPLLESTSSGGESAATTSSSSNSYGGGILSSVKKAFIGRSRSVSQEASHVPHRAATINVTSRPKKSISSTSSSTSARTHSPIRDEEVVKPYRKEWEISSQESPDNEHDSDTGMESMSSTEMSGQTRASSCTFCVDDFHVAANHQSSDAKRLETLCVDVTRLQNEKHDLLRQNVSCKTDIKKLKDRQSVLSEELERANDEISRLRRMLKKPSNSDMAPVHQHFERSYSDVSV
Protein: Spermidine synthase 1 (SPDSY 1) (EC 2.5.1.16) (Putrescine aminopropyltransferase 1) (Q9ZUB3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- S-adenosylmethionine decarboxylase proenzyme 1
- S-adenosylmethionine decarboxylase proenzyme 3
- S-adenosylmethionine decarboxylase proenzyme 2
- S-adenosylmethionine decarboxylase proenzyme 4
- N-carbamoylputrescine amidase
- Probable polyamine oxidase 4
- Probable polyamine oxidase 5
- Polyamine oxidase 3
- Polyamine oxidase 2
- Polyamine oxidase 1
Sequence:
MDAKETSATDLKRPREEDDNGGAATMETENGDQKKEPACFSTVIPGWFSEMSPMWPGEAHSLKVEKVLFQGKSDYQDVIVFQSATYGKVLVLDGVIQLTERDECAYQEMITHLPLCSIPNPKKVLVIGGGDGGVLREVARHASIEQIDMCEIDKMVVDVSKQFFPDVAIGYEDPRVNLVIGDGVAFLKNAAEGSYDAVIVDSSDPIGPAKELFEKPFFQSVARALRPGGVVCTQAESLWLHMDIIEDIVSNCREIFKGSVNYAWTSVPTYPSGVIGFMLCSTEGPDVDFKHPLNPIDESSSKSNGPLKFYNAEIHSAAFCLPSFAKKVIESKAN