wanglab/gogpt-training-data huggingface dataset:
Protein: Replication-associated protein A (EC 3.1.21.-) (EC 6.5.1.1) (RepA) (P03631)
Organism: Enterobacteria phage phiX174 (Isolate Sanger) (Bacteriophage phi-X174)
Function: Plays an essential role in viral DNA replication. Binds the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII). In turn, viral DNA replication initiates in the presence of host Rep and DNA polymerase III at the 3'-OH of the cleavage site. After one round of rolling circle synthesis, protein A is linked to the newly synthesized ssDNA and joins the ends of the displaced strand to generate a circular single-stranded molecule ready to be packed into a virion.
Interaction partners:
Sequence:
MVRSYYPSECHADYFDFERIEALKPAIEACGISTLSQSPMLGFHKQMDNRIKLLEEILSFRMQGVEFDNGDMYVDGHKAASDVRDEFVSVTEKLMDELAQCYNVLPQLDINNTIDHRPEGDEKWFLENEKTVTQFCRKLAAERPLKDIRDEYNYPKKKGIKDECSRLLEASTMKSRRGFAIQRLMNAMRQAHADGWFIVFDTLTLADDRLEAFYDNPNALRDYFRDIGRMVLAAEGRKANDSHADCYQYFCVPEYGTANGRLHFHAVHFMRTLPTGSVDPNFGRRVRNRRQLNSLQNTWPYGYSMPIAVRYTQDAFSRSGWLWPVDAKGEPLKATSYMAVGFYVAKYVNKKSDMDLAAKGLGAKEWNNSLKTKLSLLPKKLFRIRMSRNFGMKMLTMTNLSTECLIQLTKLGYDATPFNQILKQNAKREMRLRLGKVTVADVLAAQPVTTNLLKFMRASIKMIGVSNLQSFIASMTQKLTLSDISDESKNYLDKAGITTACLRIKSKWTAGGK
Protein: Ras-related protein Rab-33A (Small GTP-binding protein S10) (Q14088)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Autophagy-related protein 16-1
- Ras-related protein Rab-33B
- TBC1 domain family member 25
Sequence:
MAQPILGHGSLQPASAAGLASLELDSSLDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQKLEFPQEANSKTSCPC
Protein: Parathion hydrolase (EC 3.1.8.1) (Phosphotriesterase) (PTE) (P0A434)
Organism: Brevundimonas diminuta (Pseudomonas diminuta)
Function: Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unknown. Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease. It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate.
Subcellular location: Cell membrane; Peripheral membrane protein.
Interaction partners:
Sequence:
MQTRRVVLKSAAAAGTLLGGLAGCASVAGSIGTGDRINTVRGPITISEAGFTLTHEHICGSSAGFLRAWPEFFGSRKALAEKAVRGLRRARAAGVRTIVDVSTFDIGRDVSLLAEVSRAADVHIVAATGLWFDPPLSMRLRSVEELTQFFLREIQYGIEDTGIRAGIIKVATTGKATPFQELVLKAAARASLATGVPVTTHTAASQRDGEQQAAIFESEGLSPSRVCIGHSDDTDDLSYLTALAARGYLIGLDHIPHSAIGLEDNASASALLGIRSWQTRALLIKALIDQGYMKQILVSNDWLFGFSSYVTNIMDVMDRVNPDGMAFIPLRVIPFLREKGVPQETLAGITVTNPARFLSPTLRAS
Protein: Transcription factor BHLH9-like protein (Q8GRJ1)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDAGATARSSSSSAMMMNQKKPLSDGELVELLWQDGGVVAHAQTRHRSSDVLARSGVTGEEETASAWFADGGGGGGGDDDALGLGMGRDIYSQLWHSFANVDGHAAGALALATPTPTPRAAARSDDVSSRLDEADLSICGSNAVVAPALPADDDDDIDAAAPREEEEEEEEGPGAARAAGASSSGGSGSGSGSYPLFKRGREELVDSLSEVADETRPSKRPAAKRRTRAAEVHNLSERRRRDRINEKLRALQELVPHCNKTDKASILDEAIEYLKSLQMQVQIMWMTTGIVPMMFPGTHQLMPPMGMGLNTACMPGAQAQGLNQMQRTTYYMNNSLPNQMPQIPSPAMNAPSVPDDMQNDNRIRGPRNPFLHCNDTLTATAQVPGLFTYGSQIAEQNEIQELLSGAVIPSSSDGTIK
Protein: SANT domain-containing protein (H8ESF4)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPEFFNGKNKSKTPDVYVAYRNFMVDTYRLNPFEYVSATACRRNLAGDVCSIVRLHSFLEQWGLLNYQVDSDARPAPVAPPPTSHFMVLADTPTGIQPMNPPGKESAGASGEPPKEEIKTEIESISTPGLKIDQYQKQAIAMRTKGAPPGRDWTEQETCLLLEALEMFKDDWNKVCDHVGTRTQHECVLKFLQLPIQDPYLTENLSSDKAEAAPGGAAKEVLGPLAFQPVPFSQSGNPVMSTVAFLASVVDPQVAAAATKAAMEEFGKLKEEIPPLVAEAHEKNVAAMAEKTGQVDGAVGLTKSGLKPAEEAAGDSDEKMDTNTNDDVPSTTEAKSAIDKGVQAAAASCLAAAAVKAKHLAQIEERRIKSLVAQLVETQMKKLEMKLRHFDELEQIMDKERESLEYQRHQLILERQAFHMDQLKYLENRAKHEAHSRMTSSGALPAGLPPGFEVTGPPQPTPQVQISAQEAAIPEKMDTSEAATAARPPSTPQAPQAPPVQAAPAPVQAPQAPQAPPQAYQGYGGPGGPPQQAYRYPPQQGQQYSPYPPPQQQQQHQAQQAQSQAHYGPPGGGQGPPPPPQGQQYYGGPPPPGQPYGPPGGYPPQQQRPPYQAQPYPGPPPPQQQRGYGYPPPPQPGHPYQQPYGQMPPPPHGQYQPQQQQGGPMGPPGGHHEGGDGGDSQQKQE
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Q5ALM6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Nucleoporin NSP1
- Ran GTPase-binding protein
- Nucleoporin
- GTP-binding nuclear protein
- Large ribosomal subunit protein uL13m
- Pre-mRNA-processing factor 17
- Mitochondrial 54S ribosomal protein YmL10/YmL18
- FG-nucleoporin
- GTPase-activating protein
- Large ribosomal subunit protein uL3m
Sequence:
MFKTTLTKPLTFKSARFFSTTPRAWGTKVFFNTSINGEKQPPITFELYDDVTPITAENFRVLCTGEKGVGYKGSIFHRIIPQFMLQGGDFETGKGYGGYSPTHNNDKFNDENFIKKHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGFDVVKKIESCGTSSGTPSASVVIEESGEAEK
Protein: Maternal DNA replication licensing factor mcm6 (EC 3.6.4.12) (Maternal minichromosome maintenance protein 6) (mMCM6) (xMCM6) (Q5FWY4)
Organism: Xenopus laevis (African clawed frog)
Function: Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development.
Subcellular location: Nucleus {ECO:0000269|PubMed:9214646, ECO:0000269|PubMed:9214647}. Chromosome {ECO:0000269|PubMed:9214646, ECO:0000269|PubMed:9214647}. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. {ECO:0000269|PubMed:9214646, ECO:0000269|PubMed:9214647}.
Interaction partners:
Sequence:
MELGGPAAAGDTDIAGQQLFKDELSDKCQKLFLEFLEECKGKDGSNLYVSAAEELIRPERNTLAVNFTDIEYYNQQLATTIQEEYYRVYPHLCRAVRSFARQMGNIPANKEFYIAFSDFPARQKIRELSSAKIGTLLRISGQVVRTHPVHPELVSGTFLCMDCQSIVKDVEQQFRYTQPTICKNPVCANRRRFTLDTNKSRFVDFQKVRIQETQAELPRGAIPRSVEIILRAEAVESAMAGDRCDFTGTLIVVPDVSALAAGDARMETGAKVTGGEGFNSEGVQGLKALGVRDLSYRLAFLACYVGATNPRFGGKDLREEDQTAESIKNQMTVQEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEIKRGVLLMLFGGVPKTTMEGTSLRGDINVCIVGDPSTSKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVKDEESHEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVGGRYERSKSLKHNVNLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHARNEESIERVYSIEDIQRYLLFARQFQPKITKEAEEFIVEQYRRLRQRDGSGVAKSSWRITVRQLESLIRLSESMARMHCSDEVQPKHVKEAFRLLSKSIIRVDTPDVSFDQGEDEKNIEGENNGNLNNGEEAMETNQDEPINEKPSSNAGLKMSFAEYKQISNLLVLYMQKMEETEEECHLTTTDLVNWYLKEMEAEIETETELILKKRLIEKVIHRLIYYDHILIELNKSELKTMDDTKETGEDAAEDRILVVNPNYMLED
Protein: Eukaryotic translation initiation factor 6 (eIF-6) (O94476)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03132, ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03132}. Note=Shuttles between cytoplasm and nucleus/nucleolus. {ECO:0000255|HAMAP-Rule:MF_03132}.
Interaction partners:
- Ribosome biogenesis protein rlp24
- Ribosome biogenesis protein erb1
- Ribosome biogenesis protein nsa2
- Ribosome biogenesis protein ytm1
- Probable nucleolar GTP-binding protein 1
- Large ribosomal subunit protein eL31
- Ribosome biogenesis protein nsa1
- 60S ribosomal export protein nmd3
- Ribosome assembly factor mrt4
- Pescadillo homolog
Sequence:
MALRAQFENSNEIGVFSNLTNSYALVALGGSENFYSVFEAELGDVVPVVHTTIGGTRIIGRLTCGNRKGLLVPSSTTDNELQHLRNSLPDPVKIQRVDERLSALGNIVACNDYVALVHPDIERETEEIIADVLDVEVFRQTVAGNVLTGSYCALSNQGALVHPRTSIQEQDELSSLLQVPLVAGTINRGSDVIGAGLVVNDWCAFAGLDTTATELAVCESIFKLQDAQPSAIISNRDTLVESYT
Protein: Multidrug resistance protein CDR2 (P78595)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Multidrug efflux transporter. Confers resistance to azole antifungal agents, to other antifungals (terbinafine, amorolfine) and to a variety of metabolic inhibitors.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Multidrug resistance protein 1
- Lanosterol 14-alpha demethylase
- Transcription factor TAC1
- Major facilitator superfamily multidrug transporter FLU1
- Delta
- Sphingoid long-chain base transporter RSB1
Sequence:
MSTANTSLSQQLDEKPWVDASDNSSVQEYQGFDATASHNIQDLARKLTHGSTNGDHHSANDLARYLSHMSDIPGVSPFNGNISHEQLDPDSENFNAKYWVKNLKKLFESDSDYYKPSKLGVAYRNLRAYGIANDSDYQPTVTNALWKFTTEAINKLKKPDDSKYFDILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERHYRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYGLSHTRNTNVGNDFVRGVSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRALKTSATILDTTPLIAIYQCSQDAYELFDNVVVLYEGYQIFFGKASKAKEYFENMGWKCPQRQTTADFLTSLTNPAEREPLPGYEDKVPRTAQEFETFWKNSPEYAELTKEIDEYFVECERSNTGETYRESHVAKQSNNTRPSSPYTVSFFMQVRYVIARNFLRMKGDPSIPLISILSQLVMGLILASVFFNLRKSTDTFYFRGGALFFSVLFNAFSSLLEILSLYEARPIVEKHRKYALYRPSADALASIISELPVKLLMTMSFNIVYYFMVNLRRTAGNFFFYWLMCASCTLVMSHMFRSIGAVTTTIATAMSLSTVFLLAMIIYAGFVLPIPYILGWSRWIRYINPVTYIFESLMVNEFHGREFECGQYIPSGPGFENLPVENKVCTTVGSTPGSTVVQGTEYIKLAYQFYSSHKWRNFGITVAFAVFFLGVYVALTEFNKGAMQKGEIVLFLKGSLKKHKRKTAASNKGDIEAGPVAGKLDYQDEAEAVNNEKFTEKGSTGSVDFPENREIFFWRDLTYQVKIKKEDRVILDHVDGWVKPGQITALMGASGAGKTTLLNCLSERVTTGIITDGERLVNGHALDSSFQRSIGYVQQQDVHLETTTVREALQFSAYLRQSNKISKKEKDDYVDYVIDLLEMTDYADALVGVAGEGLNVEQRKRLTIGVELVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALIMAEFDKLLFLQKGGRTAYFGELGENCQTMINYFEKYGADPCPKEANPAEWMLQVVGAAPGSHAKQDYFEVWRNSSEYQAVREEINRMEAELSKLPRDNDPEALLKYAAPLWKQYLLVSWRTIVQDWRSPGYIYSKLILVISSSLFIGFSFFKSKNNLQGLQSQMLAVFMFFVPFTTFIDQMLPYFVKHRAVYEVREAPSRTFSWFAFIAGQITSEIPFQIVVGTISYFCWYYPVGLYANAEPTDSVNSRGVLMWMLLTAFYVYTSTMGQLAISLNELIDNAANLATTLFTLCLMFCGVLAGPNVIPGFWIFMYRCNPFTYLIQAILSTGLANAKVTCAPRELVTLKPPMGETCSSFIGPYTEAAGGYFSTNSDGTCSVCRIDSTNQFLESINALFSQRWRNFGIFVAFIGINIILTIFFYWLARVPKGNREKKMKK
Protein: ATP-dependent DEAD/H RNA helicase, putative (EC 3.6.1.-) (Q38AL9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Ribosome biogenesis protein NOP53
- Ribosomal RNA processing protein 45
- Ribosomal RNA processing protein 4
- RNasePH-like protein exosome-associated protein 1 Rrp42 homologue
- Exosome complex exonuclease RRP40
- Ribosomal RNA-processing protein 43
- Exosome component CSL4
- Cell differentiation protein, putative
- rRNA biogenesis protein, putative
- U3 small nucleolar RNA-associated protein 14
Sequence:
MQDDIPVDGEPCVKRCRHETVPAMTFPYELDAFQRDSINALENGDSVLVSAHTSAGKTTVALYAIAKAVREKKRVIYTSPIKALSNQKFREFTDKFDSVGLMTGDTTIKVDSDCLVMTTEILRSMLYRGTEMLREVGCVVFDEVHYMRDKSRGVVWEETISLLPEGCQYVFLSATIPNAREFAEWVESIHPGTKVHVIHTDYRPVPLHHYVYPCGADGIFLIVDELGKFREDNFRRAMASVGAGNKGGDANGAESTEVAAASRGKQRSMRKSTEPIMEIIKLVMNRNMYPIIVFSFAKAECERNALALSKLNFNNTEEDALVTEVFNNAMECLATEDRKLPAIEHLLPLLKRGVGIHHSGLLPILKEVVEILFQAGLVKVLFSTETFSMGLNMPARTVVFTSVKKFDGETNRYLTGGEYIQMSGRAGRRGLDRVGVVIAMVDEAVEPEILKQVTGGGADVLNSSFHLTYNMVLNLLRVEDVDPEFMMRRSFAQFQRLRNRPALEMKAEELTKDITSICVEHEEMFRQYAHCQEQLEKKRKQIGDFLKQPVFIRRFTNTGRLLRIRRSTDGALFNWGICRSSRAKTSNADEKDPSSFSVDALVICRKADPSQPTQLVPCHVKDHTINTADLYTVTFDFTDIEAVSRFRVNLPADLDSASSRAEVIQSLEKLYKNHGDDVPLLTSEELGVKDPKFKKLCEQLGNIEKQVQKCELVCNPTEALEADYESFKKRANLERELDAIKQELDQVTQAIFSDELKKMMRVLRRLDYIDKDNIILRKARVACEITTSDENELLLTELLFKGVLNSMETEMIVALMSCLVNVHRTPDGFSLPEEFRQPLNDLNEIVNRIATLSIESGITQENTSVEKTMPSLMEVTYLWAKGAKFSDIVTKTNAYEGDIVRMMRRLEEQLRQMAGAARSPAIGCMELHDKFLKGIQLIKRDIVFASSLYL
Protein: Nucleotide sugar epimerase/dehydratase WbpM (Q9HZ86)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable NAD-dependent epimerase/dehydratase WbpK
- UDP-N-acetyl-D-glucosamine 6-dehydrogenase
- Bifunctional protein GlmU
- O-antigen translocase
- UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase
- Glycosyltransferase WbpL
- GDP-mannose 4,6-dehydratase
- O-antigen chain length regulator
- UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase aminotransferase)
- GDP-6-deoxy-D-mannose reductase
Sequence:
MLDNLRIKLLGLPRRYKRMLQVAADVTLVWLSLWLAFLVRLGTEDMISPFSGHAWLFIAAPLVAIPLFIRFGMYRAVMRYLGNDALIAIAKAVTISALVLSLLVYWYRSPPAVVPRSLVFNYWWLSMLLIGGLRLAMRQYFMGDWYSAVQSVPFLNRQDGLPRVAIYGAGAAGNQLVAALRLGRAMRPVAFIDDDKQIANRVIAGLRVYTAKHIRQMIDETGAQEVLLAIPSATRARRREILESLEPFPLHVRSMPGFMDLASGRVKVDDLQEVDIADLLGRDSVAPRKELLERCIRGQVVMVTGAGGSIGSELCRQIMSCSPSVLILFEHSEYNLYSIHQELERRIKRESLSVNLLPILGSVRNPERLVDVMRTWKVNTVYHAAAYKHVPIVEHNIAEGVLNNVIGTLHAVQAAVQVGVQNFVLISTDKAVRPTNVMGSTKRLAEMVLQALSNESAPVLFGDRKDVHHVNKTRFTMVRFGNVLGSSGSVIPLFREQIKRGGPVTVTHPSITRYFMTIPEAAQLVIQAGSMGQGGDVFVLDMGPPVKILELAEKMIHLSGLSVRSERSPHGDIAIEFSGLRPGEKLYEELLIGDNVNPTDHPMIMRANEEHLSWEAFKVVLEQLLAAVEKDDYSRVRQLLRETVSGYAPDGEIVDWIYRQRRREP
Protein: Small ribosomal subunit protein bS18c (30S ribosomal protein S18, chloroplastic) (P0C476)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS14c
- Small ribosomal subunit protein uS2c
- Small ribosomal subunit protein uS12cz/uS12cy
- S5 DRBM domain-containing protein
- Large ribosomal subunit protein uL23m
- Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein
- Small ribosomal subunit protein mS29
- Large ribosomal subunit protein mL54
- Small ribosomal subunit protein uS11c
- Uncharacterized protein
Sequence:
MYTSKQPFHKSKQTFHKSKQTFRKSKQTFRKFKQPFRKPKQPFRRRPRIGPGDRIDYRNMSLINRFISEQGKILSRRINRLTLKQQRLITLAIKQARILSFLPFRNYENEKQFQAQSISIITGPRPRKNRHIPPLTQKFNSNRNLRNSNQTLRNNNRNLSSDC
Protein: Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase) (Q9EPL9)
Organism: Mus musculus (Mouse)
Function: Oxidizes the CoA-esters of 2-methyl-branched fatty acids.
Subcellular location: Peroxisome {ECO:0000305}.
Interaction partners:
- Peroxisomal bifunctional enzyme
- Enoyl-CoA hydratase, mitochondrial
- Sterol carrier protein 2
- Peroxisomal multifunctional enzyme type 2
- Trifunctional enzyme subunit beta, mitochondrial
- 3-ketoacyl-CoA thiolase A, peroxisomal
- 3-ketoacyl-CoA thiolase B, peroxisomal
- Trifunctional enzyme subunit alpha, mitochondrial
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- Long-chain specific acyl-CoA dehydrogenase, mitochondrial
Sequence:
MGSLPEEKDSALWSDTPKGPLSAYRARASFNSGELLLFWDGQDVIHFKKTIFSTLENDPLFARSYGADLPLEKLRELNFLRCKRVFEYGFFKVEELLKNPLKILVLINCLGMYDWSLANKCVLHMLVFGTTVFVSGSEKHFKYLEKIYSLEIFGCFALTELSHGSNTKAMRTTAHYDPDTQEFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYMPDGQCHGLHSFLVQIRDTKTLLPMTGVMVGDIGKKLGQNGLDNGFAMFNKVRIPRQNLLDRTGNITSEGTYNSPFKDVRQRLGASLGSLSSGRISIISMSVVNLKLAVSIAIRFSATRCQFGPTDKEEIPVLEYPLQQWRILPYLAAAYALDHFSKTIFMDLIEVQSARLRGDHSDQQAELGREIHALASAGKPLASWTAQRGIQECREACGGHGYLAMNRFGDLRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEPPLQDGAHFTSPLKTVDFLEAYPGILGQKFLGSSKADWMDSAAPLAAYRWLVCYLLQESHRRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHIHSSGLSPSLRTVLGRLSTLYGLWCLSQHMALLYRGGYISGEQTGRAMEDAILTLCEQLKDDAVALVDVIAPSDFVLNSPIAKADGELYKNLWAAVLQQNGVLERAAWWPEFSANKSVADRLKSQL
Protein: Dpr-interacting protein iota (IP10422p) (Q4V3F0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGRRLPSFWLLLLQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTDRIITVHHKAKKHGQHSHQTSSRESQFIVIEEYIANMSDKSCSFQPLWIMFLCFVNKVSLL
Protein: Scribble planar cell polarity protein (A0A8I6ANK4)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MLKCIPLWRCNRHVESVDKRHCSLQVVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPVELGGLALLTDLLLSQNLLQRLPEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPRSLGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHLNLKALWLAENQAQPMLRFQTEDDAQTGEKVLTCYLLPQQPLPSLEDPGQQSSPSESCSDAPLSRVSVIQFEDPLEGEEDAEEAAAEKRGLQRRATPHPSELKVMKRGIEERRNEAFVCKPDPSPPSPSEEERRLSAESALSGNSVPSASTASDGEPETLPAEVQGLGQQEAMPGQEEYPEEDYNEPTVHFAEDTLIPREDGEGEEGQPEAPWPLPSGRQRLIRKDTPHYKKHFKISKLPQPEAVVALLQGVQTDREGPTAGWHNGPHTPWAPRAHEEEEEEENRDEEEGEASMEEDDKEEAVASAPSVKLTLTIVRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAAHAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRERMVEPENAVTITPLRPEDDYSPREWRGGGLRLPLLQPETPVPLRQRHAACLVRSEKGLGFSIAGGKGSTPYRAGDAGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSLLTAASTTISLLLERETGGAYPPSPPPHSSSTPTATVAATMTTAIPGEPLLPRLSPSLLATALEGPYPVEEICLPRAGGPLGLSIVGGSDHSSHPFGVQDPGVFISKVLPRGLAARCGLRVGDRILAVNGQDVREATHQEAVSALLRPCLELCLLVRRDPPPPGMRELCIQKAPGEKLGISIRGGAKGHAGNPCDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHAEAVQLLRSVGDTLTVLVCDGFDTSTTTALEVSPGVIANPFAAGLGHRNSLESISSIDRELSPEGPGKEKELASQTLPWEPESAETTGRNQEPLKLDYRVLAAVPSAGSLQRGPCATTGGKMTEAPSSPGSQQPPSPDELPANVKQAYRAFAAVPTVHPPENSATQPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQQKRAQMLREEAVTSGPDTGLASDRESLDDEQEAEQPWAGPSHAGGLSPSSPTPLGGSAPVRTAKAERRHQERLRMQSPELPAPERALSPAERRALEAEKRALWRAARMKSLEQDALRAQMVLSKSQEGRGKRGPLERLAEAPSPAPTPSPTPLEDFGLQTSTSPGRLSPDFVEELRTLDPSPSPGPQEEDGEVALVLLGRPSPGTVGPEDMTLCSSRRAMRPGRRGLGPVPS
Protein: Polymerase cofactor VP35 (Marburg VP35) (mVP35) (P35259)
Organism: Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980))
Function: Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.
Subcellular location: Virion. Host cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MWDSSYMQQVSEGLMTGKVPIDQVFGANPLEKLYKRRKPKGTVGLQCSPCLMSKATSTDDIIWDQLIVKRTLADLLIPINRQISDIQSTLSEVTTRVHEIERQLHEITPVLKMGRTLEAISKGMSEMLAKYDHLVISTGRTTAPAAAFDAYLNEHGVPPPQPAIFKDLGVAQQACSKGTMVKNATTDAADKMSKVLELSEETFSKPNLSAKDLALLLFTHLPGNNTPFHILAQVLSKIAYKSGKSGAFLDAFHQILSEGENAQAALTRLSRTFDAFLGVVPPVIRVKNFQTVPRPSQKSLRAVPPNPTIDKGWVCVYSSEQGETRALKI
Protein: FtsK/SpoIIIE domain-containing protein (Probable DNA translocase coupling protein) (Q1PLI0)
Organism: Clostridium perfringens
Interaction partners:
Sequence:
MIFLSSDWEKKVNQEIENGANAIINEIANVLRIFFFRVGLGFKKSWKNKKLFIGFFLSFLIPIAARIKSDYFLVDTKFYFKIIYFLTFIAPLFYMVIVSFVKNKEDKRNAEYRLAFEQLNFVGADSKTPILKSFIEDKGTRIDEITFESMIPIETWKSYIPQLQTSLNISIISIEQGASKRIVIIKSMAGDAKIPKYLPWDDKYIEEQEGVVVVGQTFSGNIKIDLNKSPHILSAGETGSGKSVILRCILWQLLKQGAIAYMVDFKGGVEFGLEYEKVGQVITEVDAAEKLFKYLVDENAKRLKLLRESGSKNIGEYNKKFEGEELKRIIVVIDELAELMDKTGVDDETRAKLVRIEGYTSTLARLSRATGINLCIGVQRPDAKVITGQIKNNVPVRICGRFADSKASEIVLSNTKAKDLPEVKGRFLFKLGADTVQFQAFYFDDDKHFIPNKILKLRKDEIEDKKVGLDLNKEKLIDNDLMNSVNEKFEIKEVKSMDSNIENEDDSKFENFEEQNKTENLKSTINDDYE
Protein: histidine kinase (EC 2.7.13.3) (Q1D4V8)
Organism: Myxococcus xanthus (strain DK1622)
Interaction partners:
- Frizzy aggregation protein FrzCD
- Flagellar motor switch protein FliM
- protein-glutamate methylesterase
- Flagellar motor switch protein FliM
- protein-glutamate O-methyltransferase
- Frizzy aggregation protein A
- histidine kinase
- histidine kinase
- Chemotaxis protein CheW
- Protein-glutamate methylesterase/protein-glutamine glutaminase 4
Sequence:
MDTEALKKSLLKKFQEVTADRLQKIQLGVLDLEKETADQAAEDVARELHTMKGEARMLGLAAIGQLAHAAEDVLRAEREGKTATEVATDVLLRACDVLSDLNEDLSGANTGNPASEEMVRMLAEVSGQTPPAIAGARPVAPPPAPPPAPVAAPVVTPAAVAAPPAPVQAPVAPPPTQAPVAEPGAHAAAAAPHPAAAHGRDEEAPSAAKSAVADRSIRVNVEVLDALGLLAGDLLVESARGRLRSSETEALFERFSRLGDRFLRLAEEIDISNEVREQLDRVESDLHMLRDDAFRFVRRNDDGINTLHGNLAKMADHVAEARLVPLSTVFDAFPRAVREMSRTQGKEVDLVIENADIGVDRSMLGDVRDALVHLLRNSVDHGVESPDTRQQLGKPLNGRIRIRVRVDGDMLHIEVEDDGRGIDPERLRQAAISKRLINAVQAAALSEREAIELIFRPGFSTRDQVSELSGRGVGMDVVKRKVETLGGSVGVSSRIGRGSTITLRLPQSLALMKVLLVRLGDDVYGMPAADVEAVMRVKPDDRLEIFGTLAVRHRGKPTALVALGPLLGLNGGNRFDKPPAVVVRHGEDHAALVVDGFVDEREVAVKPCGGEFLKAAPFIAGTAALEDGRIAVLLHVPDIMAEVRRMARPVTQAPAAKRLRVLLVDDSPIARATEGALVKALGHSVEEAQDGEEAYVKVQNNTYDLILTDVQMPKLDGFSLARRLKSTPAVARIPVIILSSLASPEDKRRGLDAGADAYLVKGELGVEVLAQAIDRLT
Protein: Cytadherence high molecular weight protein 3 (Accessory adhesin protein 3) (Cytadherence accessory protein 3) (Q50360)
Organism: Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
Function: Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism.
Subcellular location: Cell projection, attachment organelle membrane. Note=Localizes specifically to the attachment membrane.
Interaction partners:
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
- P30 adhesin
- Cytadherence high molecular weight protein 2
- Putative serine/threonine-protein kinase
- Cytadherence high molecular weight protein 1
- Adhesin P1
- Protein P200
- Uncharacterized protein MG328 homolog
- Uncharacterized protein MG316 homolog
- Chaperone protein DnaK
Sequence:
MTDKERAKLAKAYGKLAQKIQKSYPDINVVYGRDAKNKLHALYQDPETGNIFSLEKRKQLPADYPLFELDSDEPISFAPKIIPLTAFDGNNNEVIVQYDQVNNTFYDQDGNVLDVSGYRDGENIPLVDYLNYGGSTASADTTTSEPLSGEGYPDIDAGLPVVDPDATPEQQADQLFGLDPLPQAPDEYQDTTAPPAYDQTFDQATYDQQAYDQNYDPNAYYDQQAYDQSFDQQAYDQAYDANAYNTQNYDQAHDPNAYYDSQAYSDPDQASAVAPIEVAPLQPEPVAPVVEPTAVPIVESAPIVEVTPTVEPTPTPVVETAPVVEAPKVVEPTPTPVVEATPAPKVEPKVVEQPQPTPVTVEVDSPKVEIPKVVTAKVALQVAQPTPVPAVPKVAPQPTPAPVVVQPTAVVQPVVKAEPKVVTPTPAPQVVVTPQVATPKVTPKVVQTTPAVPPVVVQPEVVVQPIIRPTQPEPEWKPSPASVVEPQPCQSACVNNESGAITIHTTNRSLLLEKLASLGHLHDASTRTPLPHERYQLAPPSEYVATKYNEPLFNLPAIRNSWARFTRPTVESTPIASRFTGVTPMAVNYRNPASLNFDSLNSFGAYRSPSSFYPLRRPLELSSLRRNRSSFFNTHRFDLGSNYTSFTPRYRSPLRGGLSQRFPLRSSWSKEF
Protein: Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)] (Q3LXA3)
Organism: Homo sapiens (Human)
Function: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.
Interaction partners:
- Triosephosphate isomerase
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- Glycerate kinase
- Interferon-induced helicase C domain-containing protein 1
- Fructose-bisphosphate aldolase B
- Fructose-bisphosphate aldolase A
- Sorbitol dehydrogenase
- Fructose-bisphosphate aldolase C
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase 1-like protein
Sequence:
MTSKKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTNASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLPAWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQPDPGAVAAAAILRAILEVLQS