wanglab/gogpt-training-data huggingface dataset:
Protein: Cardiotrophin-like cytokine factor 1 (B-cell-stimulating factor 3) (BSF-3) (Novel neurotrophin-1) (NNT-1) (Q9UBD9)
Organism: Homo sapiens (Human)
Function: In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). Also stimulates B-cells. Binds to and activates the ILST/gp130 receptor.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Cytokine receptor-like factor 1
- Ciliary neurotrophic factor receptor subunit alpha
- Leukemia inhibitory factor receptor
- Interleukin-6 receptor subunit beta
- Ciliary neurotrophic factor
- Cardiotrophin-1
Sequence:
MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWTPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF
Protein: At1g55840/F14J16_2 (Sec14p-like phosphatidylinositol transfer family protein) (Q8W580)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- SEC14 cytosolic factor family protein / phosphoglyceride transfer family protein
- Transmembrane protein
- AT3g10210/F14P13_19
- Sec14p-like phosphatidylinositol transfer family protein
- Sec14p-like phosphatidylinositol transfer family protein
- At4g35750
- Appr-1-p processing enzyme family protein
Sequence:
MSITNEEAVKQLRALMEDVDDSLRESYRNIHQGYPTENLLRFLKARDGNVQKAHKMLLECLEWRTQNEIDKILTKPIVPVDLYRGIRDTQLVGVSGYSKEGLPVIAIGVGLSTYDKASVHYYVQSHIQMNEYRDRVVLPSASKKQGRPICTCLKILDMSGLKLSALSQIKLMTAITTIDDLNYPEKTETYYVVNVPYIFSACWKTIKPLLQERTKKKIQVLKGCGKDELLKIMDYESLPHFCRREGSGSGRHISNGTVDNCFSLDHSFHQDLYDYVKQQALVKGSGAPIRHGSVHVKFPEPDTEGNKIFDTLENEFQKLGNDQKI
Protein: T4 RNA ligase 1-like N-terminal domain-containing protein (Q38AF2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEVLVERCLFKREWNGANVEDIVECAHSGKAHFIATGAFNSLVVKESHQGDVESLPIAARTLLLSADTSEIVVRGVNKFFDIEDVERDLLMWKGDVAKLQGIWLQRKLAGFVVTLFSLDGKSLGVVTKHVVEGPHVDIAYHILESMLSTEQRRRLARDLFELRAAVSCECISLKDDSHHPVPERTVFDNKLVVFSIHKRDDMREVSVPPDIMQKMAKEWGFPSVPCWRVKNCEELITWLGERQHWEGKDPAGEALAEGYVVVIEDTVQRVSPESQSISPFTALLIRLKAKTVKYRVLRSLRSIVSGESAAHPLLFHKILGSWTEHISGYTCLQQAVTNRGVHQIYSEFESYINDQGNKRYRGSHLSVQEAYKGLLGFTEKEAQTISYAPLDVIFLCGLPGVGKTTLARLIGEMGGNGCSTFRYILHLSRDEVAKCVAEHHGINDSSSKHKKRRLRSMVHQFVQRAFRQSILLSFLLEGPGLLIFDACNAKPSTRQRWRYMLPRELASFRIVYLACAERNILASRIAGRRNHSVLRGAEEAQAALYAVGKEFVAPLESEPCFCLDAAAASTEDLARSVLLLYEETNGPAPSCRHRATVYDHQQAERELTKHCATFATSILGDHYNDSMTLARSLEVSRKKAVNTVAVQLLVKFDELYEIISDVVKSITVVVDLPKLSWWERCKRGLGLGNRRRPGVVEKGHTHWLRGWLLDGREVGETPPESVWFRALEDRYECQPALPHVTVFHGPTSAATWVSVPAIGSAVDVTLHSVLIDPFALCLGATVVLNGRRQELQLSPGCAVPLHVTVGHTRRVKASYAGEMFDLFQQRESHNRKLEHMRLGFSVKKSRSKFFNFVQVRLAEQVNVRGVVVVV
Protein: ATP synthase F(0) complex subunit e, mitochondrial (ATPase subunit e) (ATP synthase membrane subunit e) (Q00361)
Organism: Bos taurus (Bovine)
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Subcellular location: Mitochondrion. Mitochondrion inner membrane.
Interaction partners:
- ATP synthase F
- ATP synthase peripheral stalk subunit F6, mitochondrial
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit b, mitochondrial
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- ATP synthase F
Sequence:
MVPPVQVSPLIKLGRYSALFLGMAYGAKRYNYLKPRAEEERRLAAEEKKKRDEQKRIERELAEAQEDTILK
Protein: PICALM interacting mitotic regulator (I3L2R2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XWLVETQVKARRRKRGAQKGSGSPTHSLSQKSTRLSGAAPAHSAADPWEKEHHRLSVRMGSHAHPLRRSRREAAFRSPYSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQELDEAIMAEESGDIVSLIHD
Protein: Presenilin 1 (G3V2G7)
Organism: Homo sapiens (Human)
Subcellular location: Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004520}.
Interaction partners:
Sequence:
MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYK
Protein: Somatic embryogenesis receptor kinase 1 (AtSERK1) (EC 2.7.10.1) (EC 2.7.11.1) (Somatic embryogenesis receptor-like kinase 1) (Q94AG2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Phosphorylates BRI1 on 'Ser-887' and CDC48 on at least one threonine residue and on 'Ser-41'. Confers embryogenic competence. Acts redundantly with SERK2 as a control point for sporophytic development controlling male gametophyte production. Involved in the brassinolide signaling pathway. Probably required during small peptide (e.g. RGF1) signaling (Probable). Involved in the perception of phytosulfokine and subsequent signal transduction. Acts as a RLK5 coreceptor and promotes high-affinity IDA sensing, thus being a positive regulator of floral abscission.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11397085, ECO:0000269|PubMed:16231101, ECO:0000269|PubMed:16284305, ECO:0000269|PubMed:16621602}; Single-pass type I membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16231101}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Protein BRASSINOSTEROID INSENSITIVE 1
- Protein phosphatase 2C 70
- Receptor-like protein kinase 5
- Probable inactive receptor kinase At1g27190
- Phytosulfokine receptor 1
- Protein TAPETUM DETERMINANT 1
- Protein IDA
- Protein IDA-LIKE 1
- CLAVATA3/ESR
- Cell division control protein 48 homolog A
Sequence:
MESSYVVFILLSLILLPNHSLWLASANLEGDALHTLRVTLVDPNNVLQSWDPTLVNPCTWFHVTCNNENSVIRVDLGNAELSGHLVPELGVLKNLQYLELYSNNITGPIPSNLGNLTNLVSLDLYLNSFSGPIPESLGKLSKLRFLRLNNNSLTGSIPMSLTNITTLQVLDLSNNRLSGSVPDNGSFSLFTPISFANNLDLCGPVTSHPCPGSPPFSPPPPFIQPPPVSTPSGYGITGAIAGGVAAGAALLFAAPAIAFAWWRRRKPLDIFFDVPAEEDPEVHLGQLKRFSLRELQVASDGFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRERPPSQPPLDWPTRKRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEEFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQTNYEERELEQVIQVALLCTQGSPMERPKMSEVVRMLEGDGLAEKWDEWQKVEILREEIDLSPNPNSDWILDSTYNLHAVELSGPR
Protein: DUF614 domain protein (AFU_orthologue AFUA_1G14190) (Q5BFC1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Flavoprotein, putative
- Pantoate--beta-alanine ligase
Sequence:
MSNEWTNSVWGCFSPIETCFMSWCCPCMVYGKQSERLQDPALKNGSNVNGDCCLFVLANCCGLAWVLSMMKRRDMREKFGIKGSVGEDCILSCCCPCCVLVQQEKELDAQASRFQSATGYQAPTSMAYTPA
Protein: NADH-ubiquinone oxidoreductase chain 6 (EC 7.1.1.2) (Q2F994)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Mitochondrion membrane {ECO:0000256|RuleBase:RU004430}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU004430}.
Interaction partners:
Sequence:
MILSVLSSPALVSGLMVVRAKNPVHSVLFPILVFCDTAGLLILLGLDFSAMISPVVHIGAIAVSFLFVVMMFNIQIAEIHEEVLRYLPVSGIIGLIFWWEMFFILDNETIPLLPTHRNTTSLRYTVYAGKVRSWTNLETLGNLLYTYYSVWFLVSSLILLVAMIGAIVLTMHRTTKVQRQDVFRRNALDSRRTIMRRTTDQITIY
Protein: Receptor-type guanylate cyclase gcy-28 (EC 4.6.1.2) (GCY-X1) (Q86GV3)
Organism: Caenorhabditis elegans
Function: Guanylate cyclase involved in the production of the second messenger cGMP. Regulates olfactory perception in AWC sensory neurons although may not be involved in the primary sensory transduction steps.
Subcellular location: [Isoform c]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, dendrite {ECO:0000269|PubMed:18817734}. Cell projection, axon {ECO:0000269|PubMed:18817734}. Perikaryon {ECO:0000269|PubMed:18817734}. Note=Excluded from the neuronal sensory cilia. {ECO:0000269|PubMed:18817734}.; SUBCELLULAR LOCATION: [Isoform d]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, dendrite {ECO:0000269|PubMed:18817734}. Cell projection, axon {ECO:0000269|PubMed:18817734}. Perikaryon {ECO:0000269|PubMed:18817734}. Note=Enriched in the axon of AWC sensory neurons. Is excluded from the neuronal sensory cilia. {ECO:0000269|PubMed:18817734}.
Interaction partners:
- Guanine nucleotide-binding protein alpha-17 subunit
- Cyclic nucleotide-binding domain-containing protein
Sequence:
MLRWLTLLSCILLTALHGNIVEDVGAAQQASYPPPPPPFPFNVIVILPKRESTYDNFGMTLQKAMPVIDIAVQEVIKAKKLPPGWINLTYWDSRLYEDILLAERHATVGVIQAYCEHRLDAILGFADNYGLATVTKVTAGLNGGIPILTTSGMPSLLNSKKEYPFLTRMQGSYRLLADSMYQLIAYHDEDSVSKSNSSLNYLNLIFFYHDKRRAVNRVIAQDESQETGATSSHCYFSLYAIKRYFTEKSKTFKREWALNTPQFPFDEDLVIERETFKQWLREISLQSNVIILCASPDTVREIMLAAHDLGMATSGEYVFINIDVSTGSHAEQPWIRANDTNNEENEKAKEAYRALKTISLRRSDLDEYKNFELRVKERADQKYNYTNITGKDYEMNNFISAFYDAVLLYAIALNETIQSGLDPRNGHNITSRMWGRTFVGITGNVSIDHNGDRYSDYSLLDLDPVQNRFVEVAYYSGASNQLKTVGQLHWVGGKPPTDLPICGYDKSKCPGYPLHVYLLMGSFLLILVLVGLFIFFWRRYKLEQELAAMSWKIRWEELDGEESQKKNEKKKAKKRKNHNDYLPESDPLLRSTSRSSVNSDKFDEDSLIPIRFRLRSSSSGTTRKISAMIDRKLSIFTRKKSTPPSESQKNGGLTPNSLQKAENGDCSPINEVQFRLPLNDRRVSSPSSEATRKKNSNEEDPENGAKKSLSLKNRKLSFGMVSFKSGSGGSVETIAQNNTQIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGLHRLHCLEEINLEEIGEHAYYKKMLWTAPELLRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALENEDLSPNEIVQRVRKPVSEDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPEVSSVRKAVRSLNRDNETSNLVDNLLKRMEQYANNLEGLVEERTQEYLAEKKKVEELLHQLLPPAIADTLIAGRAVQAESYDCVTIYFSDIVGFTSLSSQSTPMQVVTLLNDLYLAFDGVVDNFKVYKVETIGDAYMVVSGLPERRDDHANQIAQMSLSLLHKVKNFVIRHRPHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDILMQEAGFKLELRGSVEMKGKGMQTTYWLRGYKDVEIPDFGEEFA
Protein: Catenin beta 1 (A0A1D5NYE8)
Organism: Gallus gallus (Chicken)
Interaction partners:
- ICAT domain-containing protein.
- Lymphoid enhancer-binding factor 1
- APC regulator of WNT signaling pathway
- Cadherin-1
- Glycogen synthase kinase 3 beta
- Beta-transducin repeat containing E3 ubiquitin protein ligase.
- HMG box domain-containing protein.
- Presenilin-1
- Axin 2
- Axin-1
Sequence:
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTTQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRPDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL
Protein: Glutamate receptor 2.9 (Ligand-gated ion channel 2.9) (O81078)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Glutamate-gated receptor that probably acts as non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Putative disease resistance protein At4g11170
- WRKY family transcription factor
- Nucleic acid-binding proteins superfamily
- At5g40020
Sequence:
MKTNNTFLSYFVCGFLLMGVGLGQNQTSEIKVGVVLDLNTTFSKICLTSIKMAVSDFYADHPNYLTRLTLHVRDSMEDTVQASAAALDLIKTEQVSAIIGPINSMQADFMIKLANKTQVPTITFSATSPLLTSIKSPYFVRATIDDSSQVRAIASIFKFFRWRRVVAIYVDNEFGEGFMPFLFDALQDVEVKRSVIPPEAIDDEIQKELRKLMERQARVFVVHMESSLALRVFQIARDIGMMEEGYVWLMTNGMTHMMRHINNGRSLNTIEGVLGVRSHVPKSKELGDFRLRWKRTFEKENPSMRDDLNVFALWAYDSITALAKAVEKANTKSLWYDNGSTLSKNRTDLGNVGVSLYGPSLQKAFSEVRFNGLAGEFKLIDGQLQSPKFEIINFVGNEERIIGFWTPRDGLMDATSSNKKTLGPVIWPGKSKIVPKGWEIPGKKLRVGVPMKKGFFDFVKVTINPITNKKTPTGYAIEIFEAALKELPYLVIPEYVSFESPNNYNNLVYQVYDKTWDAVVGDITITANRSLYADFTLPFTESGVSMMVPVRDNENKDTWVFLEPWSLELWVTTGCFFVFIGFVVWLFEHRVNTDFRGPPQYQIGTSLWFSFSTMVFAHRENVVSNLARFVVVVWCFVVLVLTQSYTASLTSFLTVQSLQPTVTNVNDLIKNRDCVGYQGGAFVKDILLGLGFHEDQLKPFDSAKDADDLLSKGKSKGIAAAFDEVAYLKAILSQSCSKYVMVEPTFKTGGFGFAFPKNSPLTGEFSRAILNLTQNNVTQQIEDRWFPKKNDCPDPMTALSSNRLNLSSFLGLFLIAGTAISFSLLVFVALFLYEHRHTLGDDSEDSLWRKLKFLFKIFDEKDMNSHTFKNSAIHNISSPMTHKTPSPSTVQITPWPQSPSQNREFELRRVSFSPSEERFTTQPIIHHEDGESDIECRVEQ
Protein: Apolipoprotein E (Apo-E) (P02650)
Organism: Rattus norvegicus (Rat)
Function: APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P02649}. Secreted, extracellular space {ECO:0000250|UniProtKB:P02649}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P02649}. Extracellular vesicle {ECO:0000250|UniProtKB:P02649}. Endosome, multivesicular body {ECO:0000250|UniProtKB:P02649}. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans-dependent manner. Lipidation induces the release from the extracellular matrix. Colocalizes with CD63 and PMEL at exosomes and in intraluminal vesicles within multivesicular endosomes. {ECO:0000250|UniProtKB:P02649}.
Interaction partners:
- Apolipoprotein B-100
- Prolow-density lipoprotein receptor-related protein 1
- Low-density lipoprotein receptor-related protein 2
- Amyloid-beta precursor protein
- Apolipoprotein C-I
- Apolipoprotein A-II
- Apolipoprotein C-III
- Very low-density lipoprotein receptor
- Apolipoprotein A-IV
- Clusterin
Sequence:
MKALWALLLVPLLTGCLAEGELEVTDQLPGQSDQPWEQALNRFWDYLRWVQTLSDQVQEELQSSQVTQELTVLMEDTMTEVKAYKKELEEQLGPVAEETRARLAKEVQAAQARLGADMEDLRNRLGQYRNEVNTMLGQSTEELRSRLSTHLRKMRKRLMRDADDLQKRLAVYKAGAQEGAERGVSAIRERLGPLVEQGRQRTANLGAGAAQPLRDRAQALSDRIRGRLEEVGNQARDRLEEVREQMEEVRSKMEEQTQQIRLQAEIFQARIKGWFEPLVEDMQRQWANLMEKIQASVATNSIASTTVPLENQ
Protein: Prolactin (E5RWR3)
Organism: Meleagris gallopavo (Wild turkey)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Interaction partners:
Sequence:
MSNTGASLKGLLLAVLLVSNMLLTKEGVTSLPICSSGSVNCQVSLGELFDRAVRLSHYIHFLSSEIFNEFDERYAQGRGFITKAVNGCHTSSLTTPEDKEQTQQIHHEELLNLILGVLRSWNDPLIHLASEVQRIKEAPDTILWKAVEIEEQNKRRLEGMEKIVGRIHSGDAGNEVFSQWDGLPSLQLADEDSRLFAFYNLLHCLRRDSHKIDNYLKVLKCRLIHDNNC
Protein: BEL1-like homeodomain protein 5 (BEL1-like protein 5) (Q8S897)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- At2g35290
- Probable transcription factor KAN2
Sequence:
MAAFFLGESEMREHSSDLFMMTLNPFREQTTTTNAHDDHFYNLCFGSQQYRPRDEVGHIEQGNSSISTFSNGGVFRALAPIYLKAAQELLNEIVNVGNGSHGAKQERPVSKESTIYGVEDINGGYKPGVAALQMKKAKLISMGEMVEQRYKQYHDQMQTIISSFEQAAGLGSANSYTHMALQTISKQFRAVKDMISLQIKQINKLLGQKEFDEQLKKLGKMAHHHSNAWRPQRGLPEKAVSVLRSWLFEHFLHPYPRDLDKVMLAKQTGLTKSQVSNWFINARVRMWKPLVEELYSEEMDIEESRKGSDRYSTKGSSSKQPYNNTTSNESSNTILPAFRQGFTETETPRQNSSSSCSVVMRFTKQHMNQANFINFNGGFENYHTMDGNSVSLSLGLPHSCDQTFNNIHFESTSHGTENSAIYSSSTYQIMD
Protein: Type II secretion system protein HxcR (EC 7.4.2.8) (Q9I5N9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors from the periplasm (By similarity). Acts as a molecular motor to provide the energy that is required for the export of proteins (By similarity). The Hxc system is involved in the secretion of low-molecular-weight alkaline phosphatase L-AP (LapA). Is probably also involved in the secretion of the phosphate-binding protein PstS.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Probable type II secretion system protein
- Probable type II secretion system protein
- Type II secretion system core protein G
- Type II secretion system protein F
- Probable type II secretion system protein
- Type II secretion system protein K
- Probable type II secretion system protein
- Probable FAD-dependent monooxygenase
- Prepilin leader peptidase/N-methyltransferase
- Type II secretion system protein I
Sequence:
MSLLPYAWAKAQRALLRPGEHGATLLVSPRTPGWAISEVRQRHAPASLESVRDDELDTLLASAYSDTGSAAAVVGAAESEVDLDRLMDDIPEVTDLLDTQDGAPVIRMINALLTQAARDEASDIHIEPFETHSVVRYRVDGALRDVVAPRKALHAALVSRIKIMAQLDIAEKRLPQDGRIALRVAGRPIDIRVSTVPTGHGERVVMRLLDKQAGRLRLETLGMAPGVLAPLDNLIRQPHGIVLVTGPTGSGKTTTLYAALARLDASTSNILTVEDPVEYDLPGISQIQVNARIDMTFAVALRAILRQDPDIIMIGEIRDLETAQIAVQASLTGHLVLATLHTNDAVSAVTRLVDMGVEPFLLASSMLGVLAQRLVRRLCTHCRVEEDGGWRAVGCPACNQTGYSGRTGIHELFVIDDEIRRLVHQGRAEQDLREAARAAGMRSMREDGERWIASGSTTLEEILRVTRDA
Protein: ARM repeat superfamily protein (F6N15.2 protein) (O81325)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At5g24610
- Putative threonine aspartase
- Glutamine--fructose-6-phosphate aminotransferase 1
Sequence:
MEASLPEEVLQPLLHASDLSYSLEDCLKFLLESSKTDSGRSDLASKSILPSILRLLQLLPYPSSRHYLNLSLKVLRNLCAGEVSNQNSFVDHDGSAIVSDLLDSAIADFETVRFGLQVLANVVLFGEKRQRDVWLRFYPERFLSIAKIRKRETFDPLCMILYTCVDGSSEIASELCSCQGLTIIAETLRTSSSVGSVEDYWLKLLVSRICVEDGYFLKLFSKLYEDAENEIFSSEQAFLVRMVSDIANERIGKVSIPKDTACSILGLFRQSVDVFDFVSGERSELPTGSTIVDVMGYSLVIIRDACAGGRLEELKEDNKDSGDTVELLLSSGLIELLLDLLSKLDPPTTIKKALNQSPSSSSSSLKPCPYRGFRRDIVSVIGNCAYRRKEVQDEIRERDGLFLMLQQCVTDDENPFLREWGLWCIRNLLEGNPENQEVVAELEIKGSVDVPQLREIGLRVEIDPKTARPKLVNDT
Protein: Leucine-rich repeat protein kinase family protein (Q9SN97)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MESLKKLLLVALIATSAIHLVQAQNQDGFISVDCGLSPNEVSPYIEPFTGLQFTTDSNFIETGKLGRIQASLEPKYRKSQTTLRYFPDGIRNCYNLTVTQGTNYLIRARAIYGNYDGLNIYPKFDLYIGPNFWVTIDLGKYVNGTWEEIIYIPKSNMLDVCLVKTGPSTPLISSLVLRPLANATYITQSGWLKTYVRVYLSDSNDVIRYPDDVYDRIWGSYFEPEWKKISTTLGVNSSSGFLPPLKALMTAASPANASAPLAIPGVLDFPSDKLYLFLHFSEIQVLKANETREFEIFWNKKLVYNAYSPVYLQTKTIRNPSPVTCERGECILEMIKTERSTLPPLLNAVEVFTVVEFPQPETDASDVVAIKNIKAIYGLTRVTWQGDPCVPQQFLWNGLNCNSMETSTPPRITSLDLSSSGLTGSISVVIQNLTHLEKLDLSNNNLTGEVPDFLANMKFLVFINLSKNNLNGSIPKALRDRENKGLKLIVDKNVDNCSSGSCTQKKKFPLLIVALTVSLILVSTVVIDMTNNFQRALGEGGFGVVYHGYLNGSEQVAVKLLSQSSVQGYKEFKAEVELLLRVHHINLVSLVGYCDDRNHLALVYEYMSNGDLKHHLSGRNNGFVLSWSTRLQIAVDAALGLEYLHIGCRPSMVHRDVKSTNILLGEQFTAKMADFGLSRSFQIGDENHISTVVAGTPGYLDPEYYRTSRLAEKSDIYSFGIVLLEMITSQHAIDRTRVKHHITDWVVSLISRGDITRIIDPNLQGNYNSRSVWRALELAMSCANPTSEKRPNMSQVVIDLKECLATENSTRSEKDMSSHSSDLDRSMNFYTDMVPRAR
Protein: Squalene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE) (O13306)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
Subcellular location: Microsome membrane {ECO:0000250|UniProtKB:P32476}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P32476}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P32476}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P32476}.
Interaction partners:
- Terpene cyclase/mutase family member
- Candida glabrata strain CBS138 chromosome K complete sequence
- Squalene synthase
- C-22 sterol desaturase ERG5
- Lanosterol 14-alpha demethylase
- C-8 sterol isomerase
- Delta
- Delta
- Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating
- Hydroxymethylglutaryl-CoA synthase
Sequence:
MSLTNADETVTYDALIVGAGVIGPCVATALARKGKKVLIVEREWSQPDRIVGELMQPGGLRALRSLGMIQSINNIDAYPVTGYTVFYNGEHVDIPYPYKADLKPVEKLPGLVRDGNDKVLEDATVHKKDFEDDERERGVGLVHGRFLNNLRNICAAEPNVTRLQGNVVEILKDKKNEVVGAKVDVDSRGKVDFKAHLTFVCDGIFSRFRRELHPDHVPTVNSSFVGMSLYHAHMPHDMHGHVILGDKHMPILVYQISPEETRILCAYNAPKVPTDLKSWMTKDVQPYIPKTLRPSFDDALAQGKFKPMANSWLPARQNDVTGLCVIGDALNMRHPLTGGGMTVGLNDVVLLIKKIGDLDFSDREKVLDELLDYHFERKNYDAVVNVLSISLYSLFAADSKNLKALQKGCFKYFQRGGDCVNLPVAFLAGVLPKPLLLTRVFFAVAFYTIYLNMEERGFLGLPMALLEGIMILITAIKVFTPFLVRELIG
Protein: Alpha/beta hydrolase (Q9I3K2)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Tle cognate immunity protein 4 C-terminal domain-containing protein
- Type VI secretion system spike protein VgrG2a
- Antibacterial effector protein Tle3
- PAAR domain-containing protein
- PLD phosphodiesterase domain-containing protein
- PNPLA domain-containing protein
- Patatin-like phospholipase family protein
- Alpha/beta hydrolase
- Lipoprotein
- Type VI lipase adapter protein Tla3
Sequence:
MSSEPLEPNQDVIIPRSRDSLGRPVYKAQLTRTDNQSEKVALIRQTAPLPVIFIPGIMGTNLRNKADKSEVWRPPNGLWPMDDLFASIGALWTWAWRGPKARQELLKAEQVEVDDQGTIDVGQSGLSEEAARLRGWGKVMRSAYNPVMGLMERRLDNIVSRRELQAWWNDEALSPPGDQGEEQGKVGPIDEEELLRASRYQFDVWCAGYNWLQSNRQSALDVRDYIENTVLPFYQKECGLDPEQMRRMKVILVTHSMGGLVARALTQLHGYERVLGVVHGVQPATGSSTIYHHMRCGYEGIAQVVLGRNAGEVTAIVANSAGALELAPSAEYREGRPWLFLCDAQGQVLKDIDGKPRAYPQNQDPYEEIYKNTTWYGLVPEQNSQYLDMSDKKEGLRVGPRDNFEDLIDSIANFHGELSAAGYHSETYAHYGADDSRHSWRDLIWKGDPTPLETPGATLNDDENGTYNSWFRRGLPTIVQGPLETGNPLDASGSGGDETVPTDSGQAPALAGVKASFRHGSKGKGQANTKRGYEHQESYNDARAQWAALYGVIKITQLADWHPNDKGGT
Protein: Sushi-repeat-containing protein, X-linked (F7F384)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MPRGSRWGTGGLGQYLRPNRVAPAVFPKQAQIPFAAFGMAEPESLVPDTGAVFTFGKTKFAENIPSKFWFKNDVPICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIGFFTPSDIIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLKNKSNVCIPHEVTVGKPISWISCGYYHSAFVTTDGELYTFGEPENGKLGLPNQLLINHRSPQRVLGIPDKVIQVACGGGHTVVLTEKVVYAFGLGQFGQLGLGTFLFETSEPKIIDRIKDQKISHISCGENHTALMTDIGLMYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLKFTVQLIACGGCHMLVFATPRLGTIDETEFEEVYEPYMSTGSLSINDLSPGSSLNRSLSARLRRRERERPSCSASMVGTLPPLEGTSASTSASYFSPSSIPFRLSVNNYPEKSTSDSTEPLDSDYFEDKMNKETETENSSAVDLENFGETIDILNMIPQLSESVKPEAEGMDEQISVPNVEDTVEEEGKKEKETVEEGSLPEDALPETEGSETVVPADEKPAEMVKEENSASLLQRNLREYNENPKGHMYDRVKSSSSEILGGNEPTSKDIKKAKKISFFNRMSLTGQKLMQSANDPLPEIKPIGDQIALQSDKKDANQNHMGQNLQDTATPNMEGKSKSCTIL