wanglab/gogpt-training-data huggingface dataset:
Protein: Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (Q92823)
Organism: Homo sapiens (Human)
Function: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q810U4}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q810U4}. Cell projection, axon {ECO:0000250|UniProtKB:Q810U4}. Secreted {ECO:0000250|UniProtKB:Q810U4}. Note=Detected at nodes of Ranvier. {ECO:0000250|UniProtKB:Q810U4}.
Interaction partners:
- Gliomedin
- Contactin-2
- Ankyrin-1
- Spectrin beta chain, non-erythrocytic 4
- Neurofascin
- Contactin-1
- Neuropilin-2
- Ankyrin-3
- Ankyrin-2
- Receptor-type tyrosine-protein phosphatase zeta
Sequence:
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV
Protein: Non-selective voltage-gated ion channel VDAC3 (B0R197)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
Interaction partners:
- Zgc:172295
- ADP/ATP translocase
- ADP/ATP translocase
- Non-selective voltage-gated ion channel VDAC2
- Non-selective voltage-gated ion channel VDAC3
- Si:dkey-251i10.1
- ADP/ATP translocase
- Non-selective voltage-gated ion channel VDAC1
- Peptidyl-prolyl cis-trans isomerase
- Peptidyl-prolyl cis-trans isomerase
Sequence:
MRRSCASAAFSFSVPSRAVQSRKPVRNIDTAKHANMAVPPAYADLGKSAKDIFSKGYGFGTVKLDLKTKSQSGVEFTTGGSSNTDTGKAAGNLETKYKVKELGLSLNQKWNTDNVLTTEVTLEDQLTKGLKLGLDTSFVPNTGKKSAKLKTGYKREYMNVGCDLDFDLAGPTVHAAAVLGYEGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNGQLETAVNLAWTAGSNNTRFGIAAKYQLDKDSSVSAKVNNASLVGVGYTQSLRPGVKLTLSALIDAKNFNAGGHKVGMGFELEV
Protein: Homeobox protein SEBOX (Homeobox OG-9) (Homeobox transcription factor mezzo) (Skin-, embryo-, brain- and oocyte-specific homeobox) (Q8JJ26)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Probable transcription factor involved in the control of specification of mesoderm and endoderm. Acts in parallel with bonnie and clyde, faust and casanova in the Nodal signaling pathway.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- SRY-box transcription factor 32.
- GATA-binding protein 5
Sequence:
MALFYDQSFDLGLVQKINMETESDFIFNTNMLQFTDVTTKHMLSSPELDRTGHVEGQRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESKIQVWFQNRRARSMKSKKLITPVSRRSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLIRQALNPWPQNRPPISPDLPEILQWANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQMNCFAAHPEGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQRQALTHYPQTSLGDISDLIYKAAVVTNLEEC
Protein: Clusterin-associated protein 1 homolog (Qilin) (Q7ZVC2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q96AJ1}. Cell projection, cilium {ECO:0000305|PubMed:22102889}.
Interaction partners:
- Intraflagellar transport protein 57 homolog
- Intraflagellar transport 80 homolog
- Intraflagellar transport 88 homolog.
- Intraflagellar transport protein 172 homolog
- TRAF3-interacting protein 1
- Intraflagellar transport 52 homolog
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 56
- Intraflagellar transport protein 70A
- Intraflagellar transport 81 homolog.
Sequence:
MSFRDLRNFTEMMRALGYPRLISMENFRSPNFPLVAEILIWLVKRYEPQMEIPSDVDTESDRVFFIKAVAQFMATKAHVKLNLKRLYQADGYAVKEMLKITSILYNAMKTKENAGGDQNNDENSKFKFDLGSKIADLKLARQLGSEITAKGAALFDLLGQEEDLRESRTAAIARPLEITETERAMRAAVKDVTESIQMTKDLLNNVSSDEASLEAKIEKKKQDLERNQKRLQTLQSVRPAFMDEYEKIEEDLEKQYQTYVEKYRNLSFLEQQLDDYHRVEQERFEEAEMAMKMRQNKLKEEEKRLMRSGVARDEDSDVDIPEDEGSDSDIDDGQQARPHHPRHTQISGRGGARFIGSMRGGDSEETEDSEIDVDDDDEDDDEDGEEDEEENEDLDEDNDSLEGSSGKPGRTNQSLHPQILEESDNDF
Protein: Partitioning defective 6 homolog alpha (PAR-6) (PAR-6 alpha) (PAR-6A) (PAR6C) (Tax interaction protein 40) (TIP-40) (Q9NPB6)
Organism: Homo sapiens (Human)
Function: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization.
Subcellular location: Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:20719959}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20719959}. Note=Colocalizes with GTP-bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions. Recruited to the centrosome by a microtubule and dynein-dynactin-dependent mechanism. {ECO:0000269|PubMed:20719959}.
Interaction partners:
- Partitioning defective 3 homolog
- Protein kinase C zeta type
- Protein kinase C iota type
- Cell division control protein 42 homolog
- Protein PALS1
- Segment polarity protein dishevelled homolog DVL-2
- Protein crumbs homolog 3
- LLGL scribble cell polarity complex component 2
- Ras-related C3 botulinum toxin substrate 3
- Ras-related C3 botulinum toxin substrate 2
Sequence:
MARPQRTPARSPDSIVEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVHQIPGLDVLLGYTDAHGDLLPLTNDDSLHRALASGPPPLRLLVQKRAEADSSGLAFASNSLQRRKKGLLLRPVAPLRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQRNNVVRGASGRLTGPPSAGPGPAEPDSDDDSSDLVIENRQPPSSNGLSQGPPCWDLHPGCRHPGTRSSLPSLDDQEQASSGWGSRIRGDGSGFSL
Protein: Labd-13Z-ene-9,15,16-triol synthase, chloroplastic (EC 1.14.-.-) (Cytochrome P450 76BK1) (VacCYP76BK1) (A0A2K9RG08)
Organism: Vitex agnus-castus (Chaste tree)
Function: Involved in the biosynthesis of labdane-type diterpenoid including cleroda-dienols, and peregrinol lactones and furan derivatives, dopaminergic diterpenoids that can bind to dopamine receptors in the human pituitary gland, have probably ability to lower prolactin levels, and are used to treat menstrual cycle disorders (e.g. premenstrual syndrome and mastodynia) (Probable). Cytochrome P450 catalyzing the hydroxylation of peregrinol to form labd-13Z-ene-9,15,16-triol.
Subcellular location: Plastid, chloroplast membrane {ECO:0000305|PubMed:29315936}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDISAVVIVVSLISLAYYLLMRPDLRQGKSAKLPPGPYPLPVVGNIFQLGDKPNRSVTKLAKKYGPVMSLRLGSILNVVISSPEMAKEVLQKYDHVFSSRFVASSWTAHDHHNVSVPFLPVGNRWRKMRKLFRDVMLSHPRLDGGRAIRQTMIKNLYEYLLESSKTGKVVNIGAAATITSVNLTSVSLFSGQVFHFDEDESTEFKETFEGLTIAAGRPNLSDFFPIIKPFDIQGCKRQMAFYLGKLLEMFDKIVNERLKEMRTSPASARKNDMLDTLLDFCRDKENDMSLNDIKHVLVDLFVGASDTASRTIEWAITELLLHPDILAKAKEELKNVIGENKLVQESDIPNLPYMEAVIKEVFRVHPVGPFLIPRRLEEDTELSGYFIPKGTQIFVNVWSIHRDEKVWPNPESFEPERFLNNNIDYKGQDFVLLPFGSGRRMCPGVPLAHRMLYTMIGTFIHSFDWKFEPGVTPEKVDMNEAFGIVLHKAVPLKAIPIKA
Protein: Ahnak protein (A0JLR7)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
GDLKGPNVDMSRPDIEIEGPEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDISLPKVEGDIKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKIKMPKFSMPGFKGEGPEVDVSLPNADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLHLKVPKVKGDVDVSLPKVEGDLKGPDVDIKGPKMDINAPDMDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEVNIKAPKISMPDLNLNLKGPNVKGDVDVSIPNIEGDLKGPSLDIKSPKLDVNAPDIDVHGPEGKLKGPKLKMPDMHVSMPKISMPEIDLNLKGSKVKGDVDISGPKLEGDIKVPRVDLKGPEVDISAPKVNIDGKAKKSRFKLPKFNFSGSKVQTPEVDVKLKKPDVDITAPKVDINAPEVEVQGKVKGSKFKMPFLSISSPKVSMPDVELNLKGPKVKGDLDAAGPNLEGDFKGPKVDIKAPDVQLNAPDVDVHGPEWNLKMPKMKMPKFGVSGIKAEGPDVAVDLPKGDINIEGPSMNIEGPELNVECPEGSLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVSLPKANIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKIKKKK
Protein: Fimbrin-like protein FimI (P39264)
Organism: Escherichia coli (strain K12)
Subcellular location: Fimbrium {ECO:0000305}.
Interaction partners:
- Chaperone protein FimC
- Type-1 fimbrial protein, A chain
- Outer membrane usher protein FimD
- Type 1 fimbrin D-mannose specific adhesin
- Probable fimbrial chaperone SfmC
- Uncharacterized fimbrial-like protein SfmH
- Protein FimF
- Type 1 fimbriae regulatory protein FimB
- Type 1 fimbriae regulatory protein FimE
- Protein FimG
Sequence:
MKRKRLFLLASLLPMFALAGNKWNTTLPGGNMQFQGVIIAETCRIEAGDKQMTVNMGQISSNRFHAVGEDSAPVPFVIHLRECSTVVSERVGVAFHGVADGKNPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATGRRVTGGIANAQAWFSLTYQ
Protein: Cordon-bleu WH2 repeat (G5E8P4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDAPRALAAKPPTGRKMKARAPPPPGKPAAQNVHSEQKLPHDATLGSQQSLVYMKEALQNSTLDITVVLPSGLEKQSVVSGSHAMMDLLVELCLQNHLNPSHHVLEIWSSETQQPLSFKPNTLIGSLNVHTVLLKEKVPEERVKPGLTKAPEKSVRLVVNYLRTQKAVVRVSPEVPLQNILPVICAKCEVNPEHVILLRDNVAGEELELSKSLNELGIKELYAWDNRREMFRKSSLGNDETDKEKKKFLGFFKANKRSNSKGCVTTPNSPSLHSRSLTLGPSLSLGNISGVSMKSDMKKRRAPPPPSPKLLGQDKVSEKASLSSQADLQKKKRRAPAPPPPQQPPPSPVVPNRKEDKEENRKSTVGVGRQVPQKPPRGTARGPPQLVLPPPPPYPPPDTDVTEPVTFPGEGAGSETSELRPKLSLPLGPGSHCSMGGVSQVPAESEETASEDTTEDSGVMSSPSDAISLDSQQDSMRSKDKWSTDQEDGSDQDLAGTPELGPQKSPSWGKSGSGSSILRTEKATMPTNDDEDLFITGHLHQTLAELDEDLEGMEENYETDTSSLTNSVNGVSNHSLQEAIIPDSGVDDIPVTFIGEVSDEPFDSGLFSSRCNNATTFNTGSIASQRSHLSPSQTEHSQPFVRTSRKEPDPSPPSQDNRKRNQPTLANTSENENPVETDPTVTSLVSKLLIDDPKAKDKGKVHGSSHSEKTQAGHGINSLRVNPRDGKDESSNSAPPPWSHHGQALGGSYGLKYGLTTYKIVPPKSEMRCYDRDVSLSTGAIKIDELGNLVSPHMNGSRTISPPSAVVETDTPPIGKVKEFWRRNSMEKYLNGPAECTIKRAPSTTITATPEKPQQDNGMKAAFTVTTPQQQPASQEYGAHLEEERSRPQSAVSCSVKVPASNPTDITFLKPQRRTSSQYVASAIAKKMGPPKVHADVVRPHKATTEQCHEEAKLARSPPTRKDDAAPNLHSEARQHEHGTNQSSVCLPSNPGVQLPAGGHPKVEVNSTYGKSSTQDYPAAVHRNSYFLPGRSSHRDRVSVGQSCGFNEKQTTSNQKANSTSNFSQALDKAHPPPLLLAEARDSGRILMNGSARTPGNCEPPHSPKESTLTSYIILQTEEKPSSLSTDGQDADDTLPSSIFGPKKKFKPVIQRPLPKDVSLHSALMEAIHSSGGREKLRKTAEQTSEGRPKKPSYVEAESERSALLAAIRGHSGTLSLRKVSSLASEELQSFRNAALGAPGLDKPQQEDLGLPPPPALPPPPAPAPQAPSASVTVSRFSTGTPSNSVNARQALMDAIRSGTGAARLRKVPLLV
Protein: CaeNaCin (Caenorhabditis bacteriocin) (O44613)
Organism: Caenorhabditis elegans
Interaction partners:
- CaeNaCin
- Neuropeptide-like protein 29
- Neuropeptide-like protein 31
- FIP
- Neuropeptide-Like Protein
- Neuropeptide-like protein 28
- FIP
- Antibacterial factor-related peptide 2
- FIP
- Neuropeptide-Like Protein
Sequence:
MLRYILVLLVAIIAMSSAQWGYGPYGGYGGGYPGMYGGYGMRPYGMYGGYGMGMYRPGLLGMLIGK
Protein: Zinc finger CCHC domain-containing protein 8 homolog (Q2PE14)
Organism: Drosophila melanogaster (Fruit fly)
Function: Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. May be involved in pre-mRNA splicing.
Subcellular location: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q6NZY4}. Note=Excluded from nucleolus. {ECO:0000250|UniProtKB:Q6NZY4}.
Interaction partners:
- RRM domain-containing protein
- RNA helicase
- RT01008p
- Zinc finger CCHC domain-containing protein 7
- Combover, isoform A
- Ribosomal RNA-processing protein 42
- Nuclear cap-binding protein subunit 2
Sequence:
MDNSVILIDDSQNSVVIVDDDVEDGELEDDVVFVCPEELTRKEIEPPTDKIEEKHSNTSIQDTTEEDGDSLVFEVRFNKEAHFTSLQQQVLVALEGAFADKQIVFRDNPQELMISAFERSRTLPEEEPQDLFLIDTQPAAKLNAANVPSYKRCNADILDEQTEERKKLKAEAVNKCFRPKAQSSCFNCGDTEHSLRDCTKPRNNSRITRARKKMTSRTERYHVDTEQRFGHIRPGKISTKTRHAMGYSRGQLPFIFYRMRVLGYPPAWLEEAKVQSSGIALFNADGSEVTKSDEEEGESETFKYDVNKIVEYPGFNVQPKANCFDDFKHHNVPPFQESQSKENFIKSLGENVINGYKRKKLVDLPAPHDRVPAPSELLTSFDDYDMELEEETEDPPLPPSVPPPQPPPPEECEDGELTARSPSPSLEDLKAQQEELLQELDVNASHNTTANESKSPTDLDDTSETEVGPSAAESGNNEQSRSAPSTPFKASYEGTPLLKFSVYDRLPVGSNFKVGVSDVINFENLPDSTGKYEQMKDLLKNVREKMVKLQNEN
Protein: Calmodulin-binding family protein (F4JVX1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGLEVGSLCFKLKDGGLTSRTNSFKRDDTNRHQNSPKSTMERSLSFNSWEVPKETKTDSDFEVLETKKSTPNTLNGRNCERIQIKKPTVTPPEPFVFFSPRPVTELDAAATTLQKVYKSYRTRRNLADCAVVVEELWWRTLEGAALDLSSVSFFGEEKHETAVSKWARARKRAAKVGKGLSKDEKAQKLALQHWLEAVSPHNLNIFVTSYQRQVPYLTSKAIIEYTLMIHLLKLQIDPRHRYGHNLHFYYDVWSASKSTQPFFYWLDIGDGKDVNLEKHPRSVLQKQCIRYLGPMEREAYEVIVEDGRLMYKQGMTLINSTEEAKSIFVLSTTRNLYVGIKKKGLFQHSSFLSGGATTAAGRLVARDGILEAIWPYSGHYLPTEDNFKEFISFLEEHNVDLTNVKRCSVNEEYSSFKSTADEEEERKEVSEEVEIPSEKEERARPVFDPVKRLSCKWTSGYGPRIGCVRDYPMELQAQALEQVSLSPRVSPANSYGPIPSPRPSPKVRVSPRLAYMGIPSPRAVKC
Protein: 1,3-beta-glucanosyltransferase (EC 2.4.1.-) (Q6FUF5)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU361209}; Lipid-anchor, GPI-anchor {ECO:0000256|RuleBase:RU361209}. Membrane {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004589}.
Interaction partners:
Sequence:
MKLSAALLLLAAGQTVNALLPIHIKDYRFIKPASPNSTESENEVFYVKGIDYQPGGSSGYDPDSDSDVLSDPEQCARDAFVFQQLGINTIRVYTLNPDINHDKCMTILNNAGIYVILDVNGPHYGENLNRADPVGTYNAWYMSRVFRFIDAFKNYPNVLGFFAGNEIINDESNYAEIDPQFIRAIQRDMKEYIAKHSNRTIPVGYSAADNVDLRLPTLNYLQCNSLTGGNITKTMQESRSDFFGLNTYEWCSGSSDWKSSGFDKLNSSFSDAVIPVIFSEYGCNKNKPRTFDEVSEGLYGGLKAVFSGGLVYEYSEEANEYGLVTIDPEDGSITFKEDFENLKNQLKNSSLPTIKEKDVPKSEIFKCNASLITSEFSDFGVKNFSIPEQSKDTAYVIKWGANGTEGQILKNYTAPTTFKYEIKNVDGSVIPATITYPSSNLINELQTSSTMSVSSTSSASVTSSAKSSSVSSSTKKGKSSKSKASKSTSSGNKKARNGAEMISTPGFGTGFAAAVAAAVAALL
Protein: Melanoma associated antigen (Mutated) 1, isoform CRA_b (cDNA: FLJ22283 fis, clone HRC03873) (Q9H6H2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSRVPGPGGLGAAFSPLAGLHLALAGGLALRGCDPLPPGPPQPTTATGEEIGTRLSQMQGAVRDEAARTLVSGPWDSGGARGGGCSGPRCSLTFVSLASARLREQETRPWPGSSASHARTLGSVLSGAVGHTPEEAGVRAVGLGPLLVAVSGTRGGQYHRLRRGSAALHVRASYCLMENPPEPPSIVGS
Protein: Guanylate cyclase activator 2B [Cleaved into: Uroguanylin (UGN)] (O09051)
Organism: Mus musculus (Mouse)
Function: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport (By similarity).
Subcellular location: Secreted.
Interaction partners:
- Guanylyl cyclase C
- Guanylin
- Emerin
- Retinal guanylyl cyclase 1
Sequence:
MSRSQLWAAVVLLLLLQSAQGVYIKYHGFQVQLESVKKLNELEEKEMSNPQPRRSGLLPAVCHNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC
Protein: Resuscitation-promoting factor RpfE (EC 3.-.-.-) (O53177)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.
Interaction partners:
- Peptidoglycan endopeptidase RipA
- Uncharacterized protein Rv1954A
Sequence:
MKNARTTLIAAAIAGTLVTTSPAGIANADDAGLDPNAAAGPDAVGFDPNLPPAPDAAPVDTPPAPEDAGFDPNLPPPLAPDFLSPPAEEAPPVPVAYSVNWDAIAQCESGGNWSINTGNGYYGGLRFTAGTWRANGGSGSAANASREEQIRVAENVLRSQGIRAWPVCGRRG
Protein: GTP pyrophosphokinase (EC 2.7.6.5) ((p)ppGpp synthase) (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthase I) (P0AG20)
Organism: Escherichia coli (strain K12)
Function: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp. The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it. ppGpp activates transcription of CsrA-antagonistic small RNAs CsrB and CsrC, which down-regulate CsrA's action on translation during the stringent response.
Interaction partners:
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL10
- Large ribosomal subunit protein bL27
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein bL25
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS12
Sequence:
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
Protein: Trypsin 5 (G3UXD0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLIKLASPVTLNARVATVALPSSCAPAGTQCLISGWGNTLSFGVNNPDLLQCLDAPLLPQADCEASYPGKITNNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALKDNPGVYTKVCNYVDWIQDTI
Protein: Regulator of G protein signaling 22 (Regulator of G-protein signalling 22, isoform CRA_c) (G3V112)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNAPDEDETINVNYNIMASYTQTKDWFALAKQSQQTVSTFSLPCCVPYNKLKSPAISSVSENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKKQDVDESLTMHFSTCEEFLSSYIYFILRGAIQQIVGKPVGETPDYINFNNITKVSFDDCFESIHGKNFLSELVQTTKERSEEIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKKFIKGTLGERYWWLWMDIERLKVLKDPGRHQRHLEKMKKCYLVSNGDYYLSAEILSKFKLLDGSQWNEEHLRNIQSEVLKPLLLYWAPRFCVTHSASTKYASAELKFWHLRQAKPRKDIDPFPQMATLLPLRPKSCIPQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSSKDDVIEKGSKYMSESSKVIHLTSFTDISECLKPQLDRRYAYTEEPRVKTVSDVGALGGSDMENLLQSLYVENRAGFFFTKFCEHSGNKLWKNSVYFWFDLQAYHQLFYQETLQPFKVCKQAQYLFATYVAPSATLDIGLQQEKKKEIYMKIQPPFEDLFDTAEEYILLLLLEPWTKMVKSDQIAYKKVELVEETRQLDSTYFRKLQALHKETFSKKAEDTTCEIGTGILSLSNVSKRTEYWDNVPAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSIYIKNKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLLQKAEKKIGVWKPVESKWISSSCKIIAFRKALLNPVTSRQFQRFVALKGDLLENGLLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRKELGPYVFREAQMTIFGVLFKFWPQFCEFRKNLTDENIMSVLERRQEYNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIEALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLKKNMSAHSSQK
Protein: Uncharacterized HTH-type transcriptional regulator YahB (P77700)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized HTH-type transcriptional regulator YiaU
- HTH-type transcriptional regulator XapR
- Uncharacterized HTH-type transcriptional regulator YfiE
- HTH-type transcriptional regulator TdcA
Sequence:
MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRMETGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFYAIKRRIDTISQGIEARVRICINQLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGGGIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLHGQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMTQSLLVTRQIHNPRQDSRMLLATQHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN
Protein: Aryl hydrocarbon receptor protein 1 (O44712)
Organism: Caenorhabditis elegans
Function: Probable ligand-activated transcriptional activator. Acts as a transcriptional regulator in GABAergic motor neuron cell fate specification and development. Promotes cell-type-specific expression of guanylate cyclase genes that have key roles in aggregation behavior and hyperoxia avoidance. Has no role in carbon dioxide avoidance.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Aryl hydrocarbon receptor nuclear translocator homolog
- TPR_REGION domain-containing protein
- Heat shock protein 90
- Co-chaperone protein daf-41
- CHK kinase-like domain-containing protein
- Myb_DNA-bind_5 domain-containing protein
- Histidine kinase/HSP90-like ATPase domain-containing protein
- Zinc finger E-box-binding homeobox protein zag-1
- F-box domain-containing protein
Sequence:
MYASKRRQRNFKRVRDPPKQLTNTNPSKRHRERLNGELETVAMLLPYDSSTISRLDKLSVLRLAVSFLQCKAHFQACLHNSQFLSAGFPMSTHSYSYQPHPPIPFSNKVPTIFDLRIGTPMLDPEESNFEEISLKSLGGFILVLNDNGEIYYASENVENYLGFHQSDVLHQPVYDLIHSEDRDDIRQQLDSNFHIPTSSASNQFDVFAPQNSKYLERNVNARFRCLLDNTCGFLRIDMRGKLMSLHGLPSSYVMGRTASGPVLGMICVCTPFVPPSTSDLASEDMILKTKHQLDGALVSMDQKVYEMLEIDETDLPMPLYNLVHVEDAVCMAEAHKEAIKNGSSGLLVYRLVSTKTRRTYFVQSSCRMFYKNSKPESIGLTHRLLNEVEGTMLLEKRSTLKAKLLSFDDSFLQSPRNLQSTAALPLPSVLKDDQDCLEPSTSNSLFPSVPVPTPTTTKANRRRKENSHEIVPTIPSIPIPTHFDMQMFDPSWNHGVHPPAWPHDVYHLTQYPPTYPHPPGTVGYPDVQIAPVDYPGWHPNDIHMTQLPHGFTPDAQKLVPPHPQMSHFTEYPTPSTHHDLHHHPLKQDNFHLISEVTNLLGT
Protein: Uncharacterized protein (Q23186)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MVKIVTDGDYVPWYSRRAPPVFCFPCLPAYMGIWPARKCVLIIGALLFFFGVIILLAMLLTCIAIECAGVASALIPLALILIIVGILLFHCGYAAHLLDNHGEIPIKKTTTTTTTTVMDPESHEDEIRLFETVHREQVPNVRQGFWQFDENLSWQAASNPYPIQHTLKNCLERQPY